LOCUS       DAEPKC010000001       149273 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.001, whole genome shotgun sequence.
ACCESSION   DAEPKC010000001 DAEPKC010000000
VERSION     DAEPKC010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 149273)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 149273)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..149273
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.001"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(<1..188)
                     /locus_tag="KR294_000001"
     rRNA            complement(<1..188)
                     /locus_tag="KR294_000001"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            complement(473..667)
                     /locus_tag="KR294_000002"
     CDS             complement(473..667)
                     /locus_tag="KR294_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0238125.1"
                     /translation="MFQVINFLCLFCVGFLVLDVMIYFCKDAMDIFEGTTNVNKVKSI
                     NVWADRVRANSYSYENKIAK"
     gene            complement(976..2505)
                     /gene="lysS"
                     /locus_tag="KR294_000003"
     CDS             complement(976..2505)
                     /gene="lysS"
                     /locus_tag="KR294_000003"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HBH0238126.1"
                     /translation="MKNNQQSNEEAQIQEDLSEVLQVRRDKLKKLQESGRDPFKESRY
                     DRTHYSMDIKDNFDSLEGKTTKIAGRIMSKRIQGKAGFIDIQDQEGRIQSYVRLDAIG
                     EEEYSVFSTYDIGDIVGIEGEIFKTKKGEISVKAKSVVLLCKSLQVLPEKYHGLKDQE
                     LRYRQRYVDLIVNPEVKNAFLIRTKALKALRAYLDDRGFLEVETPILNTIAGGANARP
                     FITNHNTLHIPMYLRIANELYLKRLIVGGFDKVYEMGRMFRNEGMDLKHNPEYTAIEL
                     YQAYADYTDMMEITENVIAHMAEVATGSMIVNYQGTEINFTPPWKRMSMEDCVKEYSG
                     VDFSTINTDEEALEVAREKGIEIKPGMRRGEVINAFFEEFGEDKLIQPTFITHHPVEV
                     SPLSKRNVEDPRRTDRFEAFANKWELANAFSELNDPIDQKGRFIDQLRKRELGDDEAF
                     EMDEDFLKALEVGLPPTGGLGIGIDRVIMLLTNSPSIRDVLLFPTMKPIDNNPNKEEE
                     N"
     gene            complement(2520..2999)
                     /gene="greA"
                     /locus_tag="KR294_000004"
     CDS             complement(2520..2999)
                     /gene="greA"
                     /locus_tag="KR294_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003514606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HBH0238127.1"
                     /translation="MEENKEFLLTQEGYDKLEEELENLKVVKRKEVAERIKVAISFGD
                     LSENAEYDEAKKEQAQVEERILKLENMVRKAVIIDESKIDLNVVTIGSIVKVKDLEFD
                     EEVEYTIVGSTEADPYDGKISNESPVGKALLGRAAKEVVEVQVPDGVAKFEILEIRR"
     gene            complement(3108..4076)
                     /gene="dusB"
                     /locus_tag="KR294_000005"
     CDS             complement(3108..4076)
                     /gene="dusB"
                     /locus_tag="KR294_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HBH0238128.1"
                     /translation="MKIGNLELKNKVFLSPMAGVTDLPFRLICKEQGCGLLYTEMING
                     KALCYDDENTKKMLKIEEEEHPVAVQIFGSEPEFMGRAAEIMNDYSNEILDINMGCPA
                     PKVVKNGDGSALMKNPKLAEEVLRAVVKNSKKPVTLKIRKGWDDNSVNAVEIAKIAED
                     CGISALAIHGRTREQFYTGKADWDIIAEIKKNLSIPVIGNGDVFTIEDSINMLDKTGC
                     DAIMIGRGAQGNPWIFKRINHYMNTGEILPEPTLNEKISTAIKHLKLAVEEHGEYVAV
                     REMRKHIAWYLKGLRNSAKLRDEINKIEDYQEVVSKLEYYMEDSLT"
     gene            complement(4213..4983)
                     /locus_tag="KR294_000006"
     CDS             complement(4213..4983)
                     /locus_tag="KR294_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III pantothenate kinase"
                     /protein_id="HBH0238129.1"
                     /translation="MLLVFDVGNTNMVLGIYKGDKLVNYWRIKTDREKTSDEYGILIS
                     NLFDYDNVNISDIDDVIISSVVPNVMHSLENFCIKYCKKQPLIVGPGIKTGLNIKYDN
                     PKQVGADRIVNAVAGIEKYGAPSILVDFGTATTFCAISEKGEYLGGTIAPGIKISSEA
                     LFQSASKLPRVELAKPGMTICKSTVSAMQSGIIYGYVGLVDKIISMMKKELNCDDVKV
                     IATGGLAKLIASETKSIDYVDGFLTLEGLRIIYEKNQE"
     gene            complement(5002..5592)
                     /locus_tag="KR294_000007"
     CDS             complement(5002..5592)
                     /locus_tag="KR294_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBH0238130.1"
                     /translation="MMNTSASVRKVNVRKMTIIGVLSAISIMLSMTPLGFIPVGPTKA
                     TIMHIPVIIGAIMEGPIVGAAIGFIFGISSLLNAITNPTVTSFVFINPLVSILPRVMI
                     GVLAYYVYQLIIKATNKVYISGLITGAIGSLLNTAGVLGMIYVLYADKYLHAMGKSGS
                     AGKVIMALAAANGVPEAIVGALVVAAVATVLKKSKK"
     gene            complement(5776..6744)
                     /locus_tag="KR294_000008"
     CDS             complement(5776..6744)
                     /locus_tag="KR294_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P1 family peptidase"
                     /protein_id="HBH0238131.1"
                     /translation="MYNNILDIEGLKVGQVEDRNGLTGCTVVICEEGATCGVDVRGSA
                     PGTRETDLLDPVNMVQKVHAVVLAGGSAYGLESTCGVSRYLEEKGIGFDVGVGKVPIV
                     VGAVLFDLGVGSFKCRPDLKMGYRACEVANTDILNQGNYGAGCGATVGKIRGQEYAMK
                     GGIGSYSIKLDNGLIVSALIAVNALGDVYENGKVIAGALNDKKTETIDTYKLMKQGES
                     KGGFSVDNTTIGIIATNAKLTKAGCKKISQMGHDGYAKSIFPIHTPHDGDTIFTISTG
                     EIEADITLVGSLAVEVVEKSIINAVKKADSVENIMAYKDIVKKREI"
     gene            complement(6737..7714)
                     /locus_tag="KR294_000009"
     CDS             complement(6737..7714)
                     /locus_tag="KR294_000009"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HBH0238132.1"
                     /translation="MRDKIIEIILNNKSEFISGEELSKQLGVSRAAIWKHMKALKEEG
                     YNIESVNKKGYRLAENPTDLLSPQNIYYKLDTEFIGKNIEHLDTIDSTNEHAKRIAIN
                     SVDGTVILSEHQDMGKGRLGRRWDSKPHEGIWMSIILKPDMEPFKAPFITLIAGASVT
                     KALNNLGANTLIKWPNDVILNGKKICGILTELSAEIERTNYVVLGIGINVKIMDFEQE
                     IADKATSLYKEGYMLSRVDIVRNVLTEFEKLYLDYTVNNSKEKTLKICRDYSAIIDKN
                     IYVLKGDNRELVKCLDINEEGNLLVQRSDGSIKEIISGEVSIRGEKGYV"
     gene            complement(8029..9999)
                     /gene="ftsH"
                     /locus_tag="KR294_000010"
     CDS             complement(8029..9999)
                     /gene="ftsH"
                     /locus_tag="KR294_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HBH0238133.1"
                     /translation="MNKLLKGAGFYLLVFIIIVGIVQFSGKPTEKIKDLKFSEVYREL
                     TDENISRLYFVNQTSVEGTIKDTNTKFKSYVPTEVMGNKLADEVLDQAKAGKLTFGGE
                     AKPSTPWFVEMLPTLLLIFFMVIIWFVFMNQSQGGGGKVMSFGKSKAKVHKDDEKTRV
                     TFKDVAGLDEEKEDLQEVVDFLKNPKKYIELGARIPKGMLMVGPPGTGKTYLSRAVAG
                     EAGVPFFSISGSDFVEMFVGVGASRVRDLFEQAKKSAPAIIFIDEIDAVGRKRGAGLG
                     GGHDEREQTLNQLLVEMDGFGVNQGIIIMAATNRPDILDPALLRPGRFDRQVVVGTPD
                     VKGREAIFKVHSRNKPLSDDVKMDVLARRTPGFTPADIENLMNEAAILTARKREKKIK
                     METIEEAITKVIAGVAKKSKVISEKERRLTAYHEGGHAVCAHVLEEVSPVHQVTIVPR
                     GRAGGFTMQLPVEDKFYATKNEMKENIVVLLGGRVAEELVLKDVSTGASNDLERVTAT
                     ARSMVTKYGMSSKLGPMSFDSDDEVFLGNSFSSKRNYSEEVAFEIDQETKRIVDGAYD
                     KTRSILQENMDRLEYVAQALLIYETLDAEQFVKAFNKELPLNEIENAVTEENSSKEVE
                     EQLTIKLEKDEEERNNVIDINKNLEDKSDKDK"
     gene            complement(10033..11421)
                     /gene="tilS"
                     /locus_tag="KR294_000011"
     CDS             complement(10033..11421)
                     /gene="tilS"
                     /locus_tag="KR294_000011"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HBH0238134.1"
                     /translation="MIFDKVLSTINKHNLIQKGDKIVLGLSGGPDSVCLLHVLNRLKK
                     DFNIEIYAAHLNHQIRGIEAQKDALYVSKLCEDMGIIFFVKSINVPKYCENEGLSLEE
                     GARKLRYEMFYEIKDKIKANKIAIGHNLNDQAETVMMRIMRGTGLKGLKGIDYIRDNC
                     IIRPILDVERNEIEEYCEAYNLNPRIDKTNLENIYTRNKIRLDLLPYMKDNFNSNVIE
                     SIVRMSNSLKSDNDYIEKEAEAKFREVSNIKEKGFVEINLDDFVCLHDAIKVRVLRNS
                     IKHILGDTNFVDQRHIEDIMSLEDNSKVNKMLTLPRNIFVYRKKDSIILTNEEIVNEE
                     IEFYYNVPSNGFIKIKELKQIIETQVMSIDRYKSMKLDNSSKGFDFNKVKGGIVIRSR
                     RQGDKIKLAMGSKKVKDLFIDLKIPREERCKIPIITDSEGIICVGDYKISENYKIDEN
                     TKEVLKINFNKL"
     gene            complement(11604..12032)
                     /locus_tag="KR294_000012"
     CDS             complement(11604..12032)
                     /locus_tag="KR294_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HBH0238135.1"
                     /translation="MEEKSLSVKISINTRQYDEKGNMDTIEMTAFGKIFYKNDGIYVI
                     YKEKEEDIEITNTIKILKNQVSIKKFGAINSTMLFKCGESSTTKYVTPQGTLLIDIDT
                     RELDINIQEGEHIKLKIDYNIKVQDLFLGRNKIDIYIGTK"
     gene            complement(12049..12855)
                     /locus_tag="KR294_000013"
     CDS             complement(12049..12855)
                     /locus_tag="KR294_000013"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HBH0238136.1"
                     /translation="MNNKPIGVFDSGLGGLTVLKEIMKILPNEDIIYFGDTARIPYGS
                     RSKETIIKYTFQAINFLKTKGVKAIVIACNTATARSLKEAQEKYDIPIIGVIEAGART
                     AVSSTKNKIVGIIGTEGTISSKAYNLEISKIDESIEIVNKACPLFVPIVEEGWANTEV
                     AKLTAKIYLQELKEKNIDSLVLGCTHYPILKRTIGEEVGEHIKLVNPAKETAKDLKKI
                     LEVQNIINNTEIHGTYQYYVSDIPEKFSDIAREFLKKKIDKIQKVEIQKY"
     gene            complement(13057..13542)
                     /locus_tag="KR294_000014"
     CDS             complement(13057..13542)
                     /locus_tag="KR294_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase"
                     /protein_id="HBH0238137.1"
                     /translation="MATLLALTFIFMPIKEVFAYEPTENIKKVNKQEKNIAKKEVINL
                     SDNDLMLLSKLVAGEARGESYEGQVAVAAVVINRVLDPRFPDTIEEVIYQKNAFSVVL
                     DGSIKMAPTDSARKAAQEALYGTDPTNKAVYFWNPEIATCKWINRLNPYMRIGNHVFA
                     K"
     gene            complement(13593..14252)
                     /gene="spoIIR"
                     /locus_tag="KR294_000015"
     CDS             complement(13593..14252)
                     /gene="spoIIR"
                     /locus_tag="KR294_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein R"
                     /protein_id="HBH0238138.1"
                     /translation="MRKIKIRLGLLILSLISVISIMTIVINGEVKKVDNISKDYKDKL
                     IRFHVIANSNTDEDQELKLKVRDEVIKYLQPKLQNSKSIKESEAIIKKEYSSLEEISK
                     NIILKNGYNYSVKVGIQYSNFPTKQYSNIVLPAGEYKALKIIIGKGEGKNWWCVMFPP
                     LCFVDESNGVIDKSTDDKLKEVLTDKEYKLIKQDTPKKTSRVKIKFKVLEVVKDLEKK
                     F"
     gene            complement(14397..15077)
                     /locus_tag="KR294_000016"
     CDS             complement(14397..15077)
                     /locus_tag="KR294_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH0238139.1"
                     /translation="MENLTKLNLDNYKPLRDVVFENLREAILEGKLKPGQRLMEVQLA
                     EQLGVSRTPVREAIRKLELEGLVVMLPRKGAYVANMSLKDIMDVLEVRASLEGLAAYL
                     AAERISDEDIKKLKDISEEFKKSTLESDVDALLKLDVEFHECIFKATNNKKLIQLINS
                     LWEQVYRFRVTYMSAYDTSHNIVEEHKYLLDAIIKGDSELSKKYATEHIEKAEQFMID
                     KAMISKDL"
     gene            complement(15061..15951)
                     /locus_tag="KR294_000017"
     CDS             complement(15061..15951)
                     /locus_tag="KR294_000017"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HBH0238140.1"
                     /translation="MDFIRLKSRAKINLSIDVLGKRQDGYHFVEMIMQTIDLYDIVKI
                     KELDEDEIKVKSTSLDIPLDEDNIVYKAAKILKNKFYIKKGVEIFIEKNIPVAAGMAG
                     GSSNAAAVLVGLNHLWELRLSEDELKEIGLNLGADVPFCISGRPALAQGIGEKLTNIK
                     GLPCDTNILICKPDLFVSTKEVYQGLDLNNIKKRPNNKYLIECLKSEDIKAVSESMVN
                     ILENVTIGKHKEISDIKQVMMKNNALGSMMSGSGPTVFGLFKNKEDALIGKKELLKKY
                     KQVYVVNSSQKGVEICGEFN"
     gene            complement(16069..17619)
                     /locus_tag="KR294_000018"
     CDS             complement(16069..17619)
                     /locus_tag="KR294_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3794 domain-containing protein"
                     /protein_id="HBH0238141.1"
                     /translation="MELIKDVIKVDNRIDFGKFQTFIEAEAVVPDKKLDVYEIVKTEG
                     YISLKKIEMADGKILCRGSFNYNVIYIADDKNTISNVDGKVDINEVIEKDNVVQDMEY
                     MLFSEVEHMDCTIMNERKIKVGALMNIRGSLFEKQRLDIVKDVAQVEGIQKHRKEICF
                     QDIVGIEKAESSIRDTITINTEEIQSIISLNPCVKVKESRVTDNKVIIGGVLEINPLA
                     CTYEGELVELDRVGIEFTQFVEVPGVSDGMTEEVLLSMSDFNHIFKQNSESNTGLLEI
                     DCMACCKVKVTDEVTREVLQDAYSPQKIIKFDHKPIQLNKTLRRSEETFMVREGIRND
                     NDDIQIKDIVSVCPTMSIENSYIEGNKSIIQGIIKVEILFVPVEGLKLVYKISEEIPF
                     EHDIEMDNLTDTASVFNTACIDKVEVDLNRDQIDLIIKIKRFTEALDKKAENFIIKGE
                     DQGVYDLSKAPSIIVYICKEGDTFWNIAKKYNTTENEIAELNDIKLDEPIKPGKCLIL
                     EKKVVLVD"
     gene            complement(17713..17979)
                     /locus_tag="KR294_000019"
     CDS             complement(17713..17979)
                     /locus_tag="KR294_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HBH0238142.1"
                     /translation="MATVQTLDKIRVSLERHIGKKILLKANKGRKQIITKEGILEKVY
                     PSVFVIKLDDESNGYPRVSYSYSDLLTSNVKLQVFRDQDKLQIS"
     gene            complement(18127..18987)
                     /gene="yabG"
                     /locus_tag="KR294_000020"
     CDS             complement(18127..18987)
                     /gene="yabG"
                     /locus_tag="KR294_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation peptidase YabG"
                     /protein_id="HBH0238143.1"
                     /translation="MKVGDIVARKSHNKDIVFKIVSFGVDENNEKIAILKGIAFRVIA
                     DAYIDDLELVKAPDIKDILIDKNVENLLYKSVRKAKERQKRMTRAVPKLQLNPNTYGM
                     PGKVLQIDGDKEYLKICLDVYAQLGIPAVGVAVSEQNQYKEVRALLEKYNPDILVITG
                     HDAMTIKRGDIEDMSNYRNSSNFVKTVKEARKWQPNLDNLVIFAGACQSNYEKIISAG
                     ANYASSPGRIMIHALDPVFIVEKIACSRIDVVVPIDEVIEQTITGVKGIGGSETRGKF
                     RWAMPKTILH"
     gene            complement(19071..20009)
                     /locus_tag="KR294_000021"
     CDS             complement(19071..20009)
                     /locus_tag="KR294_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HBH0238144.1"
                     /translation="MKFIDLHCDTIAKLMENVETSELKSNKYSVDIDRLKKGDSLAQT
                     FALFVDTEEVKHPFDYCMSMANKFHEEMKKNSDEIALATNYEEIMKNQSEGKLTALLS
                     IEEGAVLEGKLENLKKFYDLGVRMMTISWNHVNELSFPHNKVEYREKGLTDFGREVVH
                     KMNELGMLVDVSHISDGGFYEIAKISSKPIIATHSNSRAMMNHSRNLTDDMIKVLANK
                     GGVTGINFFHLFLSDKSESKLEDMVRHIKHIVNVGGIDVVSLGSDFDGIDSKVEIEDI
                     SQMGKLYEPLKKEGFSEDDIEKIYYKNALRVIKEVL"
     gene            complement(20119..20280)
                     /locus_tag="KR294_000022"
     CDS             complement(20119..20280)
                     /locus_tag="KR294_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0238145.1"
                     /translation="MFILRFADDDDNLSVKDFTSLTDLKKYISENNIDKTWHQIEEVK
                     KVIPNLKEE"
     gene            complement(20290..20787)
                     /locus_tag="KR294_000023"
     CDS             complement(20290..20787)
                     /locus_tag="KR294_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SEC-C domain-containing protein"
                     /protein_id="HBH0238146.1"
                     /translation="MSLYTEWRNLSDNHESQEAEVKFWEEYLKVEAGIYNEILNNKMD
                     VVEGKVSELAEKFGTTNEFFMGFIDGISESLKEDIVLEEVEADKEVSIKIDWEKLYNN
                     MVTVEAHWLYNLQGWEDILPADQRKEIIKAYKKSKTIVKEAKIGRNDSCPCGSGKKYK
                     KCCGK"
     gene            complement(20902..21612)
                     /locus_tag="KR294_000024"
     CDS             complement(20902..21612)
                     /locus_tag="KR294_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0489 family protein"
                     /protein_id="HBH0238147.1"
                     /translation="MENYEYSGFYIEKPVGNNVFSYDKRENKSIYVPKLINGTLNDVR
                     LGNEVVFNEVDENKEIKAKGLENMVEYVLGNKKIYVFDNHNHAFYFWAKSLLKGEFTK
                     GCKLVHVDQHKDTREPENYDVDVNNLKDVFRYTNEVLNVGSFIKPALKYNIFSELIII
                     DSLYGFDLEVESEFVLDIDLDIFSSDMDYIPFELKFYKIKNLIKKAKVITIATSPYFI
                     NQEYAIKVLKELFNYDII"
     gene            complement(21788..22318)
                     /locus_tag="KR294_000025"
     CDS             complement(21788..22318)
                     /locus_tag="KR294_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0238148.1"
                     /translation="MDIRALPIRITKEEAIEIAKSGKNSLFSKLILKNKYAHEVRLHY
                     IEFKIITLKIHKTKSIFKNRRYSNDINELKILVNGSTGSGSIVQDFPTYEVVKNVDCN
                     IVQYSDKDERRVKAKANKMAMRLTHRFMGGIPEIEIVKIESIFRPYWVVFFGKVELNR
                     RVSYLPIEADGFVIGM"
     gene            complement(22335..22565)
                     /locus_tag="KR294_000026"
     CDS             complement(22335..22565)
                     /locus_tag="KR294_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0238149.1"
                     /translation="MSKLVSKVKKDLEIKWLGIDGFLVLLYFLITGFIFYGILTRNDI
                     IVGKIIPYGVMSVVIVIFFDYIYRVLKMTRKK"
     gene            complement(22580..23974)
                     /locus_tag="KR294_000027"
     CDS             complement(22580..23974)
                     /locus_tag="KR294_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter family protein"
                     /protein_id="HBH0238150.1"
                     /translation="MLTFWENGIIVIFAFILLGIGYYFSRNVKDMESYYLGNRSLPWS
                     LIVGTLVASWYGGVGTVGSVEYAAIYGISAWAVWSIAAHIGRMPLALWVGPRIHIRTN
                     ITVPDLLESFYGKHVAIIGAILMFIYCAQLGEITAMGTIGNVAWKIDKELIGLIMVGV
                     VVVLTVLGGLMGVAITDMVLFFCMVFGLTMVMPGQFEQIGGFQGLTEALKDAPQLMHP
                     TKGMSAMKALMLIVYSFGAYSDPTFYQRFSAADSPKVGRRALLTCFSLWICFDMVLTM
                     TGLIVRATYPEMAPAAGYITLVLDTLPQGIRVIFIIGILGSIISTLDSYYLAAGATLA
                     NDIYGRITKKELSQKQLVKFTRIGVCLAAVMGLSVAFRFENVYDACIFVGSIWMGSAF
                     VPIVGGLLGNGRRTSMGGILGMIVGGVTFGYFKIFPVQSFELEPLVIAIPFSFIAWMI
                     GNRIGENLNTQNNL"
     gene            complement(24100..25353)
                     /locus_tag="KR294_000028"
     CDS             complement(24100..25353)
                     /locus_tag="KR294_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH0238151.1"
                     /translation="MESKNNVKRFLIIFILAFGTTAMYSLPYMKSSFYDPMQQALALS
                     HTQIGNLLSLYGLVGMVSYFIGGWFADRFSVRKLITFSLIASGILGFYFSTFPSYSMI
                     LLIFVLWGFTTILTFFSASVKVVRMQGSESEQGRIFGFYEGLSGVSGTLISFIGLYFF
                     GKFAEITVGFKYVVWLYSAASIICGILLFFLVEEKKDSGASDEGLSIKSLLKVVTMPK
                     AWLIGLIIFSTYLVFSSLTYLSPYLSEVYVMPMTLVSALSIIRTYVIKMGASPVAGVI
                     TDKVGSSIRVMFVGFILMTVSTAAYLVIPKSTGFIWIAVINMIILSVILFGFRGIYFA
                     SVSESNISLETTGAVVGFASFIGFSPDAFYYTIAGNWLDKYGQTGYTYIFILSVVCAV
                     IGIFATYALNKINKRENKGLNNKIA"
     gene            complement(25404..26558)
                     /locus_tag="KR294_000029"
     CDS             complement(25404..26558)
                     /locus_tag="KR294_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBH0238152.1"
                     /translation="MSNNINQDLETKIIHWGHSADPTTGALATPICQTATFAAKTVEH
                     FEELCMTWGYVYTRECNPTLTELEAKLAMLENAESAISSTSGMGAITSTILALVKSGD
                     HIVSSDGIFSHTKLFMSELLSKFGVEVTFVDAVNPQNVKEAMRPNTKIVYIESPLNPS
                     LDLVDIKTIAEIAHENKSLAIVDSTFGTPIVQRPIDLGADLVIHSLTKFINGHGDTLG
                     GAVAGSKELIDLVRWPSLCCFTGASLPPMSAWMILRGMKTLDMRMKKHCENGLAVAEF
                     LEEEENVELVKYPALKSHPQYELCKTQMNGLGGGVVSFKLKDGINGLTRDQASRRLMN
                     SLELATIATSLGEEHTLVQMNGENLIRIAVGLESSNDIINDFKQAIEKLK"
     gene            complement(27118..27687)
                     /locus_tag="KR294_000030"
     CDS             complement(27118..27687)
                     /locus_tag="KR294_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBH0238153.1"
                     /translation="MIIIYGYCRVSTKNQTDNNSLYQQQQEILNKYNDAKIIKETYTG
                     TTTNRPKFEKIISSLKKGDLLVATKLDRLARSTSEGIQLIEGLFAKEVSVHILNIGLL
                     ENTSMGKFFLTTLLAVAELERNMIIERTQLGKEFAKKKKDFKDGRPKKYSNQQIQYAL
                     GLLNSKPYREVVKMTGISKSTLIRAKKSI"
     gene            27890..28117
                     /locus_tag="KR294_000031"
     CDS             27890..28117
                     /locus_tag="KR294_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBH0238154.1"
                     /translation="MNSLLKEAIDELKNIHCGEVFLLKELFKGYEWNRLEMNIRLKLG
                     KLFLYEVVTNPNLNVEVINKNSAYQQMYKKK"
     gene            complement(28336..29079)
                     /locus_tag="KR294_000032"
     CDS             complement(28336..29079)
                     /locus_tag="KR294_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HBH0238155.1"
                     /translation="MENYQSTNTCTYNILYVQFNEDFERSKYFSYDVKYPVIYNIRNQ
                     STYVNPVILNNINNAVRMTVNNFKNGLQEEEREYNNATSQNSLPKQSYWVSTSYAVTF
                     NKNYVLSMILNLMGFANNYGPKYNTLNNYNIDLTTGKELLLNDIFRDGVDYINIITDY
                     IKSQINENREMYYSNVELVIPEDQAFYLTDNGIIIYFGVDEIAPESFGIPKFELKFSD
                     FGNFINLRFYCISPDIYVQSRGRAKHFMG"
     gene            29247..30119
                     /locus_tag="KR294_000033"
     CDS             29247..30119
                     /locus_tag="KR294_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBH0238156.1"
                     /translation="MLLLADKWKDYELIDMGNGEKLERWGSYVLRRPDPQVVWPMESE
                     WALWKNPHGHYHRSNKGGGQWEHKKRYPEQWTINYKNLKFHIKPTGFKHTGLFPEQAA
                     NWDWMIEKIKKANRPIKVLNLFAYTGGATVACASAGAEVCHVDAAKGMVNWAKENIEL
                     SGLKNQTVRFIVDDVVKFVEREIRRGKKYDAIIMDPPSYGRGPKGEVWQIEEKLYSFV
                     DLCMGVLSDNPLFFLINSYTTGFSPIVLENVLSTTIGKKTNTGDIYGGELGIPASRDG
                     KILPCGIFGRWEKK"
     gene            30119..30784
                     /locus_tag="KR294_000034"
     CDS             30119..30784
                     /locus_tag="KR294_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBH0238157.1"
                     /translation="MIKVIYEDNHLLVVEKPVNILSQGDNTNDKDMVNLLKDYIKKKY
                     NKPGNVYIGLIHRLDRPVGGVMVFAKTSKAASRLSEQVRSKTFKKTYLAVVHGKIKSN
                     SDILKDFLYKNKKTNMVTVVKKSHKDAKEAELNYNVLDFKENLSLVQVNLKTGRSHQI
                     RVQFASRKHPLYGDQRYGKEINKIGQQISLWSNKIEICHPTTKEKMEFTCHPPDKYPW
                     NIF"
     gene            30805..31662
                     /locus_tag="KR294_000035"
     CDS             30805..31662
                     /locus_tag="KR294_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH0238158.1"
                     /translation="MSKKFSIGEMSKLHKISIQTLRYYDQIDLFKPVHVDQESNYRYY
                     SIDQFSQLDIIKYLKYLGMPLKEIKSKLDENNEEILKLLTNKINIVDEKIKELELIKK
                     VLSTKKETMEKGMKVDEVGKIVRKHIPRRSILSIEYEEGLSSEETMELSRRQIANILE
                     DNISVFYGGVSGLVSIDKFLKEDKVIYDNSFVTVERDLFDIKSQKHITEISSGDFICM
                     TYKGPYKENYTAFKKLVDYVEYKRIPIENYIYEIPIIDPLSTNNEEELLTEIQIQVKK
                     REIDLRCLV"
     gene            complement(31818..34364)
                     /locus_tag="KR294_000036"
     CDS             complement(31818..34364)
                     /locus_tag="KR294_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HBH0238159.1"
                     /translation="MNIFNKVALQGLKKNRTRTLVTIIGVVLSAAMITAVTTFGVSLM
                     NYMTNGAIIKYGDWHVQFLDVDSSFVQEQRVNDEVANTATFENIGYATLEGNRNPDKP
                     YLFIAGFSKEAFDTLPITLISGRLPENSREILVSSKVATDGGVKFAVGDTISLDVGKR
                     MSENEKLGQSDPYTAGSEVFVPQDKKTYTVVGICRKPVFEESSAPGYTLITKEDKQVK
                     TDSLSLFVTLKNPHQIRSYISSTKDHASIFNDNVLRFIGVSDNNLFNMFLYSVGGIVL
                     AIIMLGSIFLIYNSFNMSLNERTHQFGILSSVGATAKQLRNSVLFEGICIGAIGIPIG
                     VAIGIVSIGLVISVIAKNFANILYVNVPLTLTLSIPAIIVAAVVSMVTILISAYIPAR
                     KAANTPVMECIRQTNEVKIESKSVKTSKLTQRVYGLEGVLAMKNFKRNKKRYRSIVLS
                     LVLSIVLFISTSALVADLKQMSNQRSEVTDQDIIFSTQGMKDNEMLKLYDKLKTANGV
                     YEGLYQKLMTYSCVAKVSELTDDYLNYEGSHSMSEMLELPVDMQFLDDRTYLNIIKSL
                     GLPAEEYTGQNAKLIAVSMVTKDNNIIDIFNSSSMNVSLTPETNGKLEIPERQNVNIS
                     FVKVVPPDSPPGIRSSDVKKASFRVLAPYSAKDKFEIPGVSTGIESLSFQSKNPTQSV
                     AEMEQIIESEGVTNEYNLYNMYGMMDENRNYIFIANVFAYTFIIMISLISIANVFNTI
                     STNIKLRRRELAMLRSVGMSEHDFQKMMNFECAFYGMRALFFGLPIAVISSWLIHKVM
                     VTDDIDFVIPWFSIGISIFSVLFIVFITMLYTINKIKKENIIDALRDDMA"
     gene            complement(34364..35050)
                     /locus_tag="KR294_000037"
     CDS             complement(34364..35050)
                     /locus_tag="KR294_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0238160.1"
                     /translation="MAFLKIEDLCKVYGKNENKVTALDHVSLTIEKGEFTAIIGSSGS
                     GKSTLLHSIAGVDVPTSGKIYLEGQDVYGQSNEKLAIFRRRQVGLIYQFHNLIPTLNV
                     VENITLPILMDKRKVNQERLNDLLELLGLKERKTHLPNQLSGGQQQRVAIGRALMNAP
                     AVMLADEPTGSLDSKNGQEIIQLLKESHSKYHQTLIIVTHDENIALQADRIICISDGK
                     VVRDERKVNR"
     gene            complement(35133..36122)
                     /locus_tag="KR294_000038"
     CDS             complement(35133..36122)
                     /locus_tag="KR294_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH0238161.1"
                     /translation="MFRNREFRKFAILFLLITILTVALGFAISIMTGILSIVSATTFG
                     IAFFVFTKNRYKSIAQISEQINLVLHNANHLYIAESDEGELSILQSEITKMTLRIREQ
                     NYALKKEKEHLADSLADIAHQLRTPLTSVTLILSLLENTSDEDERKELIRETEELLIR
                     MDWLITSLLKLSRLDAGIVVFQKEQIDVNNLISSALHQLLIPMELHNITLHIDIPKGV
                     RILGDLNWLSEAIQNIFKNCMESVGDNGKIDIICEDNFLFTQLTIHDNGAGFKKEDLP
                     CLFNRFYRGKNSSTAGYGIGLALCKTIIMRQGGTITAQNHPQGGAIFVIRFPK"
     gene            complement(36109..36795)
                     /locus_tag="KR294_000039"
     CDS             complement(36109..36795)
                     /locus_tag="KR294_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0238162.1"
                     /translation="MKRIFLVEDDKAIAKNLILLLNSEGFIVTHVSTRSEALVEIAKN
                     KFDLALIDISLPDGNGFTICTEIKEKQDIPVIFLTASGDESSVVTGLNMGADDYITKP
                     FRPRELIARIRTALRKSGRFGSTFEICGLYVDTATGVVKKNGNEVFLSALEYRLLLVF
                     ISNPKSIITRVRLLDELWDAAGEFVNDNTLTVYIKRLREKIEDDPSSPQIILTVRGTG
                     YRLGGSYVSK"
     gene            complement(37295..40501)
                     /gene="carB"
                     /locus_tag="KR294_000040"
     CDS             complement(37295..40501)
                     /gene="carB"
                     /locus_tag="KR294_000040"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HBH0238163.1"
                     /translation="MPKLDSIKKTLVLGSGPIIIGQAAEFDYSGTQACQALKEEGIEV
                     VLVNSNPATIMTDKEIADKIYIEPLTIEFIEKIIEKEKPDSLLAGMGGQTGLNLAVEL
                     HDAGILDKYNVKVIGTSIESIKKGEDRDLFREVMKEINQPVIVSDIVTNLEAGLEFAN
                     KIGYPVVVRPAYTLGGTGGGIADTEEELREILSHGLQLSPVGQVLLEKSIKGWKEIEY
                     EVMRDGNGNCITVCNMENVDPVGVHTGDSIVVAPSQTLSDEEYQLLRKASIDIINAIE
                     VQGGCNVQIALNPHSLEYAIIEINPRVSRSSALASKATGYPIAKVAAKIALGYTLDEI
                     ENAVTKKTYACFEPTLDYVVVKIPKWPFDKFRHANRKLGTKMMATGEIMSIGSNFEAA
                     ILKGIRSLETGKYSLVHAPSEGRTLEELKARVVVPDDERLFDLAEMIRRGYKVEMISE
                     ITGVDKWFINKFKWIVEQEEKLKVLKIEDLDKEYLHELKKKGFSDKGISDLMKISPEK
                     LYELRSLYNIQPVYKMVDTCGGEFEALSPYYYSTYEQYDEVVVSDKRKVVVLGSGPIR
                     IGQGIEFDYCSVHCVKSLRKMGIETIIVNNNPETVSTDFDTSDKLYFEPLTEEEVLNI
                     IEKEKPEGVILQFGGQTAIKLAKFLHEKNIPILGTDFRDIDAAEDREKFDDLLERLDI
                     NRPKGKGVWTTNEGVEIAKELGYPVLVRPSYVLGGQGMEITYNEEKLIQYLDDAFDRD
                     HKNPVLIDKYLTGREIEVDAICDKEDILIPGIMEHLERAGVHSGDSTTMYPSQNISDE
                     IKEKIVEYTKKIALDLNVLGMVNIQFIEFQNELYIIEVNPRASRTVPYISKVSGVPIV
                     DLATKCMLGAKLKDLGYSTGVYKEPKLVSVKVPVFSMSKLSKVEVSLGPEMKSTGEVL
                     GVGENLEEALYKGFLAAGRHMSDERGVVLATVNNHDKDEFIEIAKDMKELGYTFVATE
                     GTAKSLRENGIEADIVNRIEEPRPNILDAIRNKQVDIVINTPTKGNDSTRDGFKMRRT
                     AIEFSTEIMTSLDTLKALVEVKKKHLNKDKLKVYNIAE"
     gene            complement(40694..41743)
                     /gene="carA"
                     /locus_tag="KR294_000041"
     CDS             complement(40694..41743)
                     /gene="carA"
                     /locus_tag="KR294_000041"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002845470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HBH0238164.1"
                     /translation="MKARLILEDGTVFIGKAFGYLEESVGEVVFNTSMIGYGEVLTDP
                     SYYGQIVTMTYPLVGNYGINLSSAESEKVQVKGFIVREKSDSPSNFRCEIDIDQYLKQ
                     NKVIGLEGIDTRALTKILRNNGTMKGIITLEDSKLEDVKHKLDKFSNTEAVRTVTRKE
                     VEHIKGNGPKVAVMDFGVKRNILRSFIARGCDITIFPATTSPEDVLSINPDLIFLSNG
                     PGDPEDLEDVIENIKALIGKKPIVGICLGHQLLALALGGKTAKLKFGHRGGNHPVKDL
                     EEGKVFITSQNHGYYVSEVPEQMKVTHINLNDNTVEGMRHEKLDVYSVQYHPEACPGP
                     KDNDYIFDKFLELVK"
     gene            complement(42000..45206)
                     /gene="carB"
                     /locus_tag="KR294_000042"
     CDS             complement(42000..45206)
                     /gene="carB"
                     /locus_tag="KR294_000042"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HBH0238165.1"
                     /translation="MPKLDSIKKTLVLGSGPIIIGQAAEFDYSGTQACQSLKEEGIEV
                     VLINSNPATIMTDKEVADKIYIEPLTIEFIEKIIEKERPDSLLAGMGGQTGLNLAVEL
                     YEKGILDKYGVKIIGTSVESIKKGEDRDIFREVMKEINQPVIVSDIVTDLQAGLDYAL
                     TIGYPVVVRPAYTLGGTGGGIADNEEELREILSHGLQLSPVGQVLIEKSIKGWKEIEY
                     EVIRDSKGNCIVVCNMENIDPVGVHTGDSIVVAPTQTLSNKECAMLKKASLDILNAVE
                     VQGGCNVQFALNPHSFEYAVIEINPRVSRSSALASKATGYPIAKVSSKIALGYTLDEI
                     ENAVTKKTYACFEPTIDYVVAKIPKWPFDKFKKANRKLGTKMMATGEIMSIGSNFEAA
                     ILKGIRSLETGKYSLVHTPSEERSIEELKKRVVVPDDERLFDLAEMIRRGYKVEMIEQ
                     ITGIDKWFINKFKWIVEQEEKLKVMKIEDLTKDYLLELKKKGFSDKGISDLMKISPEK
                     LYELRSLYNIKPAYKMVDTCAGEIDAISPYYYSTYEQYDEVVVSDKKKVIVLGSGPIR
                     IGQGIEFDYCSVHCVKSLRKMDIETIIINNNPETVSTDFDTSDKLYFEPLTEEEVLSI
                     IEKEKPEGVILQFGGQTAIKLAKFLHEKNIPILGTDFDDIDAAEDREKFDDLLERLDI
                     NRPKGKGVWSLNEGIEVANELGYPVLVRPSYVLGGQGMEITYNEEKLSQYLQDAFDRD
                     HKNPVLIDKYLTGREIEVDAICDKEDILIPGIMEHLERAGVHSGDSTTMYPSQNISDE
                     IKEKIVEYTKKIALDLNVLGMVNIQFIEFQNELYIIEVNPRASRTVPYISKVSGVPIV
                     DLATKCMLGAKLKDLGYGTGVYKEPKLVSVKVPVFSMSKLSKVEVSLGPEMKSTGEVL
                     GVGENLEEALYKGFLAAGRHMSDERGVVLATVNNHDKDEFIEIAKDMKELGYTFVATE
                     GTANSLRENGIEADIVNRVEESRPNILDAIRNKQVDIVINTPTKGNDSTRDGFKIRRT
                     AIEFSTEIMTSLDTLKALVEVKKKHLNKDELKVYNIAE"
     gene            complement(45259..46302)
                     /gene="carA"
                     /locus_tag="KR294_000043"
     CDS             complement(45259..46302)
                     /gene="carA"
                     /locus_tag="KR294_000043"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HBH0238166.1"
                     /translation="MKGKLILEDGTVFEGKAFGYLKEAIGEVVFNTSMAGYGELLTDA
                     TYYGQIVTMTYPLIGNYGINLEDVESNKVQVKGLIVREKSDNPNNFRCEMDIDTYLKQ
                     NKVIGLEGIDTRALTKIIRNNGTKRGIITLENVSLQDVQSKLEEHCNKDSVKNVTRKE
                     IENIKGTGAKVVVIDFGVKNSVLESLKACNCDITIVPAMTTVEEILNINPDLILLSNG
                     PGNPEDINDIVENIKKLIGKKPLTGIGLGHQILALALGGKTSKLVFGHRGGNHPVKCL
                     ETGKVFITSQNHGYNVSEMPENTEVTHINLNDNTIEGMRHKELPIYSVQYIPEYTTKE
                     DLDCIFNKFLALI"
     gene            complement(46328..47044)
                     /gene="pyrF"
                     /locus_tag="KR294_000044"
     CDS             complement(46328..47044)
                     /gene="pyrF"
                     /locus_tag="KR294_000044"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HBH0238167.1"
                     /translation="MINGKEKLIVAIDTDEFDKAKELIDRLEDSVDIFKVGLEQYVAT
                     KGKTIDYLKEKGKKIFLDLKFHDIPNTMKSAVKAAVRDNVWLMTIHVSDMEGMRQCAL
                     IAREEAERLNIEKPLVVGVTVLTSLSNQDLQDIGCNMTTEELAIKRAKLAKESGIDGV
                     VCSAQEVDKIVEACGTDFITVCPGIRPKSAEVGDQKRVVTPSDAIKKGAHYLVVGRPI
                     TKAENPRESAINIVREIENA"
     gene            complement(47420..48055)
                     /locus_tag="KR294_000045"
     CDS             complement(47420..48055)
                     /locus_tag="KR294_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1847 domain-containing protein"
                     /protein_id="HBH0238168.1"
                     /translation="MYKCGKCNLRGCSNGNMDKLMKICPTREIELQQKAKQLYEEEEN
                     RKIAYNAGLVEAEGYCQYTRLKEIIEFAKKCGYKKIGIAFCIGLKREMQTVQKIFEHH
                     GFEVFSVICKNGAMPKSTIGLEASQTISKCSDEVMCNPIGQALFLNEAKVDLNVILGL
                     CVGHDTLAMKYMEAPITTLVVKDRVTGHNPVAAIYNAESYFEKKLFDKDEE"
     gene            complement(48079..48993)
                     /locus_tag="KR294_000046"
     CDS             complement(48079..48993)
                     /locus_tag="KR294_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0238169.1"
                     /translation="MELYEAIFYRKSVRNFSSKKIKKPLMEEIKRSCKNLEYLNEDLN
                     IKAHVVDRGHIIHFLMGKECKVKAPHYIVVTSDKGEDYLQNIGFATEGVVLRLTTLGI
                     ATCWLEGNLKREDILEFVDIGNKNFEEDEEDDLDYLAGIKTEEDDENKIENPYIIIAF
                     GYPAKNEELFRTRYARPDRKPVKDMINKINRNRKWKDILELTRRAPSVKNSQPWYFHK
                     DERGLHLFEKRPKKHCEDMNKVSLGVALRHFDIACIKNKIDVSYEKLPIRNKIGKSYF
                     ITVVEHVKPEEETQEENVTLEKEESQDE"
     gene            49594..50823
                     /locus_tag="KR294_000047"
     CDS             49594..50823
                     /locus_tag="KR294_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HBH0238170.1"
                     /translation="MNLNRNLEKYAELAIKVGVNIQPGQILLIKSPIECADFARNALK
                     EAYKCGAKNVYIEWSDEESTLIKYLYAPDEAFHEFPKWTAEQYVDIAKEGGAFLSVYA
                     QNPDLLKDVDPERVANFQKASGKALKEWRSYTLTDKCKWNIVSVPTKDWAKKVFPNLS
                     EDKAIEKLWDAIFKCSRVDGQDPIKAWEEHNENLKSKMDFLNKNNFKTLKYKSSKTDL
                     TLDLPKGHVWLSGASKDPNGISFNPNIPTEEIFGMPHKFKVNGTVYSTKPLVYGGNII
                     DNFFLTFKDGKIIDFSAEKGLDTLEKLIETDEGSHYLGEVALVPYNSPISNTDIIFYN
                     TLYDENASCHFAIGSAYKTCLEGGNNLKDEELDEHGVNDSLTHVDFMIGSADMDIIGE
                     TYDGKQIQIFKNGNWAF"
     gene            complement(51028..53409)
                     /locus_tag="KR294_000048"
     CDS             complement(51028..53409)
                     /locus_tag="KR294_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homocysteine S-methyltransferase family protein"
                     /protein_id="HBH0238171.1"
                     /translation="MEIRQYLKNNILIFDGAMGTMLQQKGLKLGENPEVFGLQNPDKL
                     IEIHTAYLEAGSNVILTNTFGCNELKLDSKYTVEEVIDNAVLVARKAIENVDNTKPRY
                     VALDIGPIGEMLEPMGTLSFDKAYEIFKRQVLQGVKSGVDVIVIETMMDLYEAKVAVL
                     AAKENSDLPIFCTMTFDEGGRSFTGCMPECMVATIEGLGVDAIGVNCSLGPKQLLPIV
                     EKIASRATVPVMVQANAGLPNIVDGEAIYDVDAKEFFEGVKKFVEVGATIIGGCCGTN
                     PSFIKEISENINSVTKGCIEKIDKCVVCSPSKFVEVQSPTVVGERLNPTGRKSLQEAL
                     KNENVDYAINLGLEQVNAGAQILGVNVGLPEIDEKKLMPKLIREIQAVVDTPLQVDSS
                     NVEALEQGLRYYNGRTIVNSVNGKEESLESILPIVKKYGSCVVGLTLDEKGIPKKAEE
                     RFEIAKRIVNRAVSYGIKPKDIFIDCLSLTVSAQQEEAIETIKAITMVKTLGVKTILG
                     VSNISFGLPNRKALNASFLTLALGAGLDLAIINPNEYSMMEAINSFKILNNTDKGCIN
                     YINQYSNINNSKKSDSSTKIDKDLPLDILVERGLKDEAKNVTLNLLKEKDENYILDEI
                     LIPALDKVGKRYDSGDIFLPQLIQSAETVKVSLNTIKETLLSKSSNNVSKGKIIVATV
                     KGDIHDIGKNIVKIMLENYGYEVIDLGKDVPIEEVVEVAKKRNIKLVGLSALMTTTVQ
                     SMKDTIQALRDNEINAKVFVGGAVLTEEYAEEMGADYYSKDAKSAVEIAKLNF"
     gene            complement(53381..54106)
                     /locus_tag="KR294_000049"
     CDS             complement(53381..54106)
                     /locus_tag="KR294_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Vitamin B12 dependent methionine synthase,
                     activation domain protein"
                     /protein_id="HBH0238172.1"
                     /translation="MENNLIGREDISINQSEVLRYLQYRGQEIDKDLKYTIDECVAIT
                     KNKINPRYLSRIYPIRINKDNVVELEGTNLTLESKYVYELLKECNECVIMAATIGIDI
                     EKEIRRHSYSNLTKGLIIDSCGTTAIEEVCDIVQNNLEKVFLKQDKFITMRYSPGYGD
                     LPIEKNIDILNVLNAQKQIGLTITSNGIMIPRKSVVAIIGISNTRINKSKKEKSCENC
                     KNYRNCTYRKGANSCGNKTISEK"
     gene            complement(54096..54551)
                     /locus_tag="KR294_000050"
     CDS             complement(54096..54551)
                     /locus_tag="KR294_000050"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HBH0238173.1"
                     /translation="MEKVESFKLDHTKVKAPFVRKCSVLDGVKGDKVTKFDLRFLQPN
                     VESFGTAAMHGLEHLLATYLRDTLDGVIDLSPMGCRTGFYLILWGDVDAKTVKIGLEE
                     ALKKVLESDKMPAATAIECGNYRDLSLFGAKEYAKDVLDKGFSLNIYGE"
     gene            complement(54833..56014)
                     /locus_tag="KR294_000051"
     CDS             complement(54833..56014)
                     /locus_tag="KR294_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBH0238174.1"
                     /translation="MKNKSLLNHMFRPILDLIISCALTSMLILTSMYIIKSLYVNSDM
                     SVVNQLVYQARDFRSLIGYDLFYPFLFTITSLAIYSIISYKRNKQIVDFIRKTNRKNQ
                     KLEIIKSAVNLMDEGNLEKSIDIEYDLDILKDKEKDDIDELAHKINNIVHQLRNITIE
                     ERQAQQTKTDLITNVSHDLRTPLTSIMGYLGVIEEGKYKDEVQMMYYVDIAYEKSKNL
                     NVLINDLFELTKMQNNTIKLNKIEINLVELLSQVVSQFEIYFKQEFMVSRINFNEEKL
                     IVKADPNKLVRAFENLITNAVKYGKDGHYVDIVTEKKEDMAVVKVINYGEPIPVLDLP
                     NIFDRFYRVEKSRNRNVGGSGLGLAITKNIVNLHDGEITVSSDKYQTVFEVQLPIIQS
                     A"
     gene            complement(56004..56696)
                     /locus_tag="KR294_000052"
     CDS             complement(56004..56696)
                     /locus_tag="KR294_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011948339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0238175.1"
                     /translation="MNNTVLVVDDEKEIRDLIEIYLLNSGYNVIKAEDGKEALDILKK
                     ENIHLMILDIMMPKMDGIEVCRKVRESLNIPILMLSAKSEDMDKIQGIMTGADDYLTK
                     PFNPLELTVRVKSLIRRAYYFSGANNEDKDVIKVGVVIIDKEKHSVTVAGNEIILTSR
                     EFDILYLLANNKGRVYSTEEIFEKVWKEKYYQSNNTVMVHMSRIRDKIEKYTDGEKII
                     HTVWGVGYKIEK"
     gene            complement(56830..57546)
                     /locus_tag="KR294_000053"
     CDS             complement(56830..57546)
                     /locus_tag="KR294_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HBH0238176.1"
                     /translation="MKKFKLIGAIILVVFISVFISKDRLLKKDKDPIVAAQHDSEQDV
                     EANSQNKNHSNSISNILLVNKTNGISKNYTPENITKVNIPFVEEATEEEKQMAGEPAK
                     AVEDLVKQANSEGIQFLGSSAYRSYDTQLDTYTRRVKSQGREKADAYVAKPGYSEHQT
                     GLCIDLTNPERWFVGSTKEAKWLAENAHKFGFIIRYPEGKEDITGTAYEPWHIRYVGK
                     DAAEEIYSKGLTLEEYLQNK"
     gene            57671..58405
                     /locus_tag="KR294_000054"
     CDS             57671..58405
                     /locus_tag="KR294_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiocytidine(32) synthetase TtcA"
                     /protein_id="HBH0238177.1"
                     /translation="MSIQKLLSKARKAIQDFDMIQENDKIAVGLSGGKDSLTLLHILK
                     SYQRFSPQNFELIAITLNTGGVDNSPLDKLCKEINVPFYEFQTDIKEIVFDIRQEKNP
                     CALCANLRRGALNDNAKKLGCNKVALGHHKDDAIETFLMSMFYEGRVNCFSPKTYLDR
                     QDLTVIRPMVYIEEYMTKKISKDSNYPIITNPCPANGHTRREYIKNLIANLNKEMPDF
                     KRNVFGALNNSEKLFIWDKEKIKNFK"
     gene            complement(58690..59541)
                     /locus_tag="KR294_000055"
     CDS             complement(58690..59541)
                     /locus_tag="KR294_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBH0238178.1"
                     /translation="MNSKIKYFLKFFILIFILIFIYSVAIEPSLLIVKKYNISENGTL
                     IKSDTIESKSERIKVVQISDTQIGSFYSTKNLKKVANKINTLNPDIIVFTGDLIDYSN
                     KNPSVDEITTILSSMNARLGKFSVFGNHDYMYKLPRYYRQIMKNSNFNLLVNENKKIK
                     LKDDKYINILGVDEILNGNPNIKYLESQIDNKNFNLLLAHEPDLVDMLSKDTMNLVLS
                     GHSHGGQIRLPIKGALVTPPYGRKYTKGFYDINGNHLYVSSGLGSTKLPFRFFNIPEI
                     IEFNIII"
     gene            complement(59567..60505)
                     /locus_tag="KR294_000056"
     CDS             complement(59567..60505)
                     /locus_tag="KR294_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBH0238179.1"
                     /translation="MKSILIMGGSDFIGSALAKRLIKCGYQIDILTNGKKEIDYNGFK
                     EHLICDRKVRKDMENIITGRKYDYIYDMTAYTKEDVSNLIDFISMDNLKKYIVLSAGA
                     VYKDSGRNIKEENEKGENENWGKYGLNKKEAEDFIINSPIPYIIIRPTYIYGENNNLY
                     REYYFFEKIEKNEKIPVPKGKQVSNQFIYIGDLVKVLESIMKNPHVREAYNVTNPQLI
                     SWDDLIYTCGEIIGKEPIIKYVDMEKVEFRERTYFPFRNIDFNLDINKLIEHGLYIPN
                     VLLKEGLTATYKWFSANKPKMHDRKMNKVESVMQIV"
     gene            complement(60608..61258)
                     /locus_tag="KR294_000057"
     CDS             complement(60608..61258)
                     /locus_tag="KR294_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBH0238180.1"
                     /translation="MKKNYEIVLFDLDGTLTDPKEGITKSIQYSLNSFGIKEDLENLD
                     QFIGPPLHDTFKEYYKFEDKKTKEAVEKYREYFADKGIFENKIYENIKEILEMLYKNG
                     KILLVATSKPTVFAETILRYFDIDRYFKYIAGSNLDGTRVNKNEVIQYVLDLCNVKDK
                     DKVIMVGDRKYDIIGAKKIGIDSIGVLYGYGSFEELSESEPTYIVENVESIKDILL"
     gene            complement(61408..61596)
                     /locus_tag="KR294_000058"
     CDS             complement(61408..61596)
                     /locus_tag="KR294_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HBH0238181.1"
                     /translation="MKAFVDKDVCVACGACIGTCPDVFSMSDEGHSVAIEGEIPADLQ
                     DLCKEAEEGCPVSAITVK"
     gene            complement(61703..62887)
                     /locus_tag="KR294_000059"
     CDS             complement(61703..62887)
                     /locus_tag="KR294_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HBH0238182.1"
                     /translation="MKNLLIRNGTIISPTDGIKFEKRDILVLHGKIYAIGLNLKEKIR
                     KEKLLTNKEFEIINADNMYISPGFIDVHTHCYKRKLPTGMDSDSIGIEKGSTVIFDAG
                     TAGPLNYYDFKKKYMDECKTEVYSFLNVTNEGLNILNESTSLDVINFDKVESVVEKNI
                     EKIKGIKVKASKFQSNESGIDIIKKSKQVAKKLNLPLVVYIGEYPSYIDEVMNILGKG
                     DVVTPVYGNSTNGILKESGTLRKSVINAKNRGVLFDVCHGLNQFDFKVFKKAIKQGLE
                     PDLISTDMHIKNMKDVNYSLLSVINKIMELGISLEKCIEKVTEYPTKIFDLHGNKGRI
                     KIGGEGDFTIFTMEECNDIIKDYNNNELVLNKKLRLQYTVKSWMKSSEVYRHGYENTI
                     IN"
     gene            complement(63029..63946)
                     /locus_tag="KR294_000060"
     CDS             complement(63029..63946)
                     /locus_tag="KR294_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SufD family Fe-S cluster assembly protein"
                     /protein_id="HBH0238183.1"
                     /translation="MNKIDLNLLEKVAELRGTPLGAYNIRKNGQGVERHSTENVTIIP
                     KTDKPGIDIIVKPNTKGENVHIPVIVTETGVQDMVYNDFEIGENADVVIIAGCGIHNC
                     GCDDSEHNGIHRFFLRKGARLKYVEKHYGEGDGEGKRILNPVTIVNMDEDSYCEMETI
                     QIKGVDSTKREMDANLGKGAKIVVFEKLLTHGNQVAESNMKVILEGENSSAQVVSRTV
                     GQDNSKQKFNPCVIGDSLCSAHVQCDSIIMGNSQISAIPEIAANHPDALLVHEAAIGK
                     IAGDQILKMMTLGLTEEEAEQQILNCFLK"
     gene            complement(63968..64696)
                     /locus_tag="KR294_000061"
     CDS             complement(63968..64696)
                     /locus_tag="KR294_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH0238184.1"
                     /translation="MLEIKNLSFNVESNNEELGIINDVSLSFERGKLIVITGPNGGGK
                     STIAKLIMGIEKATSGQIILDGEDITNLSITERAKKGIGYAFQQPPRIKGMTVENLLT
                     LAHGKPLSTDVCCQYLTDVGLCSKDYLNREVDNSLSGGEMKRIEIATLFARDLKVSIF
                     DEPEAGIDLWSFGKLNESFKKIHEESNQTIIIISHQERILELADEIIVLQDGSVKSHG
                     TKEAILPEIMCQVNSSCELMKDMN"
     gene            complement(64892..65092)
                     /locus_tag="KR294_000062"
     CDS             complement(64892..65092)
                     /locus_tag="KR294_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0238185.1"
                     /translation="MFKKMAVLKDIATKIGRKKAYELLEMVEGNDAFVAEVKIKKNGI
                     ESKKEEIMLKDNQKIILEYIEG"
     gene            complement(65217..65597)
                     /locus_tag="KR294_000063"
     CDS             complement(65217..65597)
                     /locus_tag="KR294_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBH0238186.1"
                     /translation="MINKIGKITLYVNNQEDAKLFWTEKLNFVVTYEKEMGPNMKWVE
                     VAPSKNEFTTFVLYDKNLMMRQNKEINVSHPSIILSTRDINGTYEQMANNEVEVGELM
                     EMPYGRMFSFKDQDGNDYLVREDK"
     gene            complement(65870..67228)
                     /locus_tag="KR294_000064"
     CDS             complement(65870..67228)
                     /locus_tag="KR294_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBH0238187.1"
                     /translation="MFIRKNVIKLAIPIMIEQTFVMLLGVFNTMMAGHIGEEAVSAVG
                     MVDSINNIFISVFAALSVGATVVVAQQIGKKDGEKVNETIKQALVSGVILSFTITILM
                     WVFRTGVINLFYGSAEELVKSNAKLYIEFTLFTYPFIATQQIANGLLRGCGDVKKPMY
                     VTMFMNIVNVTLGYILIYGIDLNPLGINLQTPSYGITGAAISIAIARIIGCIVIIRAL
                     FKGNEFISMGKIFPFKIDVETQKSIFNIGIPAGVEQLLFNAGKLIVQVFIVTMGTSAI
                     ASNAIGMSIASIINVIGNALALSATTLVGQYIGRGDIKGAKSTLLYLTKFATICLFIV
                     GAIFIPIAPWISSMYTQNASVIDISTQLIRSDCLAMVIWPISFVLSAGLKGAGDTRYT
                     MMTAVIGMWIFRIFTGYVLGVVLEFGVLGIWIGMYTDWLVRGTLYCLRLRGTKWLKHK
                     VA"
     gene            67676..68128
                     /locus_tag="KR294_000065"
     CDS             67676..68128
                     /locus_tag="KR294_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0238188.1"
                     /translation="MVNLNANNLNVNMVYPISSTAPIRFRRYTVSYLENMENIYLTIA
                     TYFDTLGLGTMNIDKVYGQWAWFTDNIYDLNLFVFVGNYPYQIAKNRYDTFVDILPVA
                     ITSIVNGDRIFLISNPCLLNSKITVRFISSHPTLNRTVDYGNIRDFIF"
     gene            complement(68285..68902)
                     /locus_tag="KR294_000066"
     CDS             complement(68285..68902)
                     /locus_tag="KR294_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 domain-containing protein"
                     /protein_id="HBH0238189.1"
                     /translation="MEIFAIGHSNYPYDKLINMIKKYDINCVVDIRETPYSKYNIQYN
                     KEAFNESLRNSGFLYIYMGKEFGAKRTNKDVYTQEGYADFEKVAKEDIFLNGIERLKK
                     GCQMGYRIVLLGAMQEPIRCHRSILVGKVLNKEGFDVKYIMHEGNLAYQEDIEESLLD
                     KYFSDRKQLSIDNLLGSALTREEMIQEGYKLANKEIGYRTEKLGK"
     gene            complement(69325..70137)
                     /locus_tag="KR294_000067"
     CDS             complement(69325..70137)
                     /locus_tag="KR294_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH0238190.1"
                     /translation="MFSIGMFSKINKITTKTLRYYEDIGLLKPEYVDEFTKYRYYTTE
                     QLPKLHQIITLKQMGLSLAEIKKAVENPEEVENILMNKEKEMLDVIKSEEYKIIKLRN
                     YLMNLKGEVNMNDVIIKSLPKVKVASMRKVLKGYDELFNLFPNVMAEEMMKTGCTCAV
                     PDYCFNIYHDGEYRETDMDVEMCQAINDLKEDTDILKFKELDAVENAVCILHNGPYST
                     LGKTYADAFKWIEDNKYKVVGNPRESYIDGIWNKESEEDWLTEVQIPVKRML"
     gene            complement(70213..71631)
                     /locus_tag="KR294_000068"
     CDS             complement(70213..71631)
                     /locus_tag="KR294_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium/proton antiporter"
                     /protein_id="HBH0238191.1"
                     /translation="MTELMIISGLVLLICITSSKVLYKFGVPILLIFILLGMLFGSDG
                     MVGIYFDNYELTKQLCSIGLIFIMFFGGFGTNWNMAKPVAIPSILMSSLGVIITAGVT
                     GMFCHMVIGTSLLEGLLIGAIAASTDAASVFAVLRSQKLNLKGSLASLLEVESGSNDP
                     IAYMLTLILLTLMNNSGVELIAPMVIKQIAFGLAIGFILAKLSVYILRHSNFEIEGFY
                     TIFITAIAILSYAFSEYLGGNGYLSVYISGIIIGNSRIPLKKSLVHFFDGISWIMQIM
                     LFFMLGLLSFPSKLPNVFGIAMAISIFMIVIARPLATFIVLAKFKFSNKEKLFISWVG
                     LRGAASVVFAIYAVTQGVAIENDIFHIIFFIALLSVGIQGSLIPTVARKLDLVDDNTP
                     VLKTFNDYDGEISSKLIEVNVDEGNKWANKSIIDSNIPDDILIVMIKRKEQVLIPKGS
                     TIIKTGDILVLSGDRIEELIQL"
     gene            complement(72115..73032)
                     /locus_tag="KR294_000069"
     CDS             complement(72115..73032)
                     /locus_tag="KR294_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2268 domain-containing protein"
                     /protein_id="HBH0238192.1"
                     /translation="MVNMNIIEIRSDKIYKKIMDAPINKKEDIYRYELMKPFEFKWKC
                     MNVPIVARQKGGYDVIIASEMLGVLSPKDIDEKQKKNINVLSADKIWATCKETIENSI
                     NAFIKEGYDLNIKDYKYSILLANPNSPYTILSDGYWGDGGIPGYIFLSLVPNEYTINR
                     LPVLIAHECNHNIRFQFIEWNNNITLEEMMINEGLAENFATWMFGEEMLGPWVSRTDI
                     ETLNTYIKPIIKSALKETGFQNITSYLYGDDIAKMQGYFPVGLPYCAGYACGYYMIKY
                     YLEKTNKSIIEATLLPYSEIIEAVKEFWE"
     gene            73294..73671
                     /locus_tag="KR294_000070"
     CDS             73294..73671
                     /locus_tag="KR294_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBH0238193.1"
                     /translation="MLTPYLIFNGTCEKAFNFYAEAFGGGKTIFARLDSNPNNPIMHA
                     SVTFTKYEGCIMGADTDKPVVISGMAICVVLPSREAIEEISVKLAEGGTLVQEFLPHP
                     PPHQNDGAAEVLDRYGYTWYLST"
     gene            complement(73827..74276)
                     /locus_tag="KR294_000071"
     CDS             complement(73827..74276)
                     /locus_tag="KR294_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH0238194.1"
                     /translation="MKSGIILEMKQINSTEYDEMLQVWESSVRATHDFLTEKDIESLI
                     PLVEIGLKEVENIVCIKDNDIIKGFIGIDKDKIEMLFIEDKYRGNGIGKKLIKYAIDK
                     YNVKYVDVNEQNKKAVGFYIHLGFKVFDRSEIDGQGNPFPILHMKLI"
     gene            complement(74443..74847)
                     /locus_tag="KR294_000072"
     CDS             complement(74443..74847)
                     /locus_tag="KR294_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmaF family protein"
                     /protein_id="HBH0238195.1"
                     /translation="MSYQNYKCERDYVYDDYKYNKCNKCYNDYEEMTHVHEYSESVKL
                     AEECEDRHNHRAAGVTGEAIPINGGTNHVHKINDNVDFLDHFHKICVTTGPAIRIPGT
                     DKHIHLICGETTVNDGHCHKFLFTTQIEAPLV"
     gene            complement(74960..75826)
                     /locus_tag="KR294_000073"
     CDS             complement(74960..75826)
                     /locus_tag="KR294_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HBH0238196.1"
                     /translation="MIDIHKNIYDNKLFEELKIDCKKCFGLCCVALYFSASDGFPIDK
                     ESGKPCINLQPDFKCSVHNSLMKRGFKGCTAYDCFGSGQKVAQVTYKGIDWMQSSELT
                     NQMSEVFLIMRQLHEMLWYLKEASVLNISDTIKSKIDLIIEETEKITNMSPEQIINLD
                     IISHRIKVNLLLSQASESVMGKVKSFIKTSTLKNMKKLSKNIDLIGADLRKINLIGAD
                     LRGRFLIAANLRNTDLSGANLIGADLRDCDIRGANLENSIFLTQLQVNTAKGDSSTKL
                     PASLIRPKYWEK"
     gene            complement(76396..76740)
                     /locus_tag="KR294_000074"
     CDS             complement(76396..76740)
                     /locus_tag="KR294_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HBH0238197.1"
                     /translation="MENLPNCPKCNSEYTYEDGTLLVCPECSHEWALGLGAEEDSNII
                     KDVNGNVLNDGDSVTVIRDLKVKGSSSSIKIGTKVKNIRLIHDSSDGHDIECKIDGFG
                     AMKLKSSVVKKA"
     gene            complement(76929..77546)
                     /locus_tag="KR294_000075"
     CDS             complement(76929..77546)
                     /locus_tag="KR294_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0238198.1"
                     /translation="MISLINISKKFKDKSIIDKFNLEISKGEFVAITGNSGSGKTTLL
                     NIMGLLEKPNSGDIIINNIKNPNSKQIRILQRDFYGYLFQNYALIENENVENNLKIAL
                     KYQKNINHNKKINYALESVGLRKYNKKKIYELSGGEQQRVALARVILKECEVIFADEP
                     TGNLDKKNRDIVFDILKSLNKNGKTIVFVTHDLELSEQADRVIKL"
     gene            complement(77551..79713)
                     /locus_tag="KR294_000076"
     CDS             complement(77551..79713)
                     /locus_tag="KR294_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HBH0238199.1"
                     /translation="MKKIIYVLFTIELLIVSLLGLNIVKDNEINNILYNETTSISVMF
                     KDYKKLNKNYSKWIKDIADENNVTISKYVFNNNEKLSIYTTDTSLNNNIKLKSGKFPN
                     TNSNEFISNINTNNSNQVGKFSTMSKDISILIRDFGKISEVGESGILYISTQNEDTIN
                     KILRELNVDRSIFVARLHDRYVNSNLYLNPSIIRDLILIILCFLATIIHYSISVSREA
                     SILRLNGYSKLDIIARVIKNILRIMILSSVTALLIYIIYILKLNIGVRACLYFAMFSI
                     ICILINILISILIVGFNSRSSKYVLSLNGKKSYGFVNIMHFTLKIVFVSFLILSINNC
                     ILNYNMLQTQLGNLSEWDKAKNVYNLTLKDTGEQSLGKEEVIKNAKIKGFYKNLVEEK
                     DAFLIDSTNFEKLEDGSYMYEINSKGKNPEVSQYGKNIKINKNYLKVNPIYSNGKEIF
                     NLIDYDDKTINLLVPKKLQVHENEIKKEFRELFYFEKIEVENMYNKELNRALNKTKKS
                     DLNVNIIYVDNNQSYFTYNSLVMDDNRNLIDDPIAIVDIDNIDDSFYLSYISRCVYFN
                     SKKLDALADISSIIEAQGVEAHIQSLHAVYNEYGLEINKLEKYLNSEIFTIIIIAISN
                     LMITYNIVASYYERNKYKLYIKKIFGYSTTARSMLLIVSLILTNIIPIGIISTRVDLS
                     NNIILFGLLILVIEVIVSIVLDKIISNSSFNKIIKGEH"
     gene            complement(80055..82562)
                     /locus_tag="KR294_000077"
     CDS             complement(80055..82562)
                     /locus_tag="KR294_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HBH0238200.1"
                     /translation="MKEDIRLHRMCKKEQATKNEVISEDILKSMSIGVSKHFLDDSFT
                     IIWGNTSFYQLLGYTEEEFLVKFSSLKDYYEQNLYHFESMKNHFLEAYHHGEKSIEYQ
                     ICISANNGDPVWVIMTGILIESQDNEKSMVYILYSKINELKIKQEELSDMEKESTENF
                     KWMMSEYAGNVYISDMDTYELLYLNKHSCNTLQASANELIGRKCYEVIQGRTSPCPFC
                     TNSYLKKDDIYEWEFYNKKLKRTFIIKDRMLNWQGRRVRIELSYDMYSAEYKLAKKDQ
                     ERESILKTIPAGMVRLDARDYLTILWCNDIFLNMIEYTKEQFAEELNNQCGYLFSEDY
                     KRSKKLAQDLKESGDNVVFEAKIYTRSREERIWTVTLCYISGEDSWDGIPSFYSIGID
                     ITKERKQIEKLQHISEKDALTGIYNRAETERQIKKYFEKNLNVMGALFMIDTDNFKQI
                     NDTEGHMIGDIVLTEMASGMKKIMRDSDVVGRIGGDEFTIFMKNISSVKDAEKKAEEL
                     LYMFRHLFQKEKSFLKVTCSIGIAIYPKDGTTFKEIYARADKALYQAKNMGKNNYVIY
                     NQDYFKELEEFDCSSLGTVIDSEKQYAEYPDNLTRYIFRMLYQTDDIDQAINMILEVV
                     GKQFDVSRVYIFENTEDGRYTSNTYEWCNEGISSQMAYLQNSNYQDYEDYEKLFEDEL
                     VFYCRDIHTLSPKLEELFSSQGIHSTLQCAYKEDRVFSGFVGFDECTGLRLWSQEEIS
                     TLSLISQIISMFLQRKKNNKLNQQIQQYQNILDNIDQCICVINKENNFLLYVNKKFKN
                     TYSKFQIGQPYYLDSIDIHKISIIWNKKEAYLCTSTI"
     gene            complement(83040..83672)
                     /locus_tag="KR294_000078"
     CDS             complement(83040..83672)
                     /locus_tag="KR294_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketohydroxyglutarate aldolase"
                     /protein_id="HBH0238201.1"
                     /translation="MKKMNITKRMSECGALAIVREENLNRACEIAEGCIKGGITVIEM
                     SYTLNNAGEIIQGLNKKYGETLCVGAGTVLDSETARHAILHGAQFIIAPNYNEGVAKI
                     CNRYQIPYAPGCTSLTEAVDALSLGATFIKAFPISDFYGPKLVKVFKTPIPDMPVLAS
                     GGINIENLHIWLENGVDVCGFGGLLTKGSVEDIAKNAKKIREIIKNIRKI"
     gene            complement(83778..84683)
                     /gene="dapA"
                     /locus_tag="KR294_000079"
     CDS             complement(83778..84683)
                     /gene="dapA"
                     /locus_tag="KR294_000079"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HBH0238202.1"
                     /translation="MKYKGIICAMITPFDENQNINSQATCQLIDYLIEKGIYGLFILG
                     TNGECHVLTDDEKVEFAKIVINHTNNRVPVFVGTGGNSTREVVDLSKRMEAIGASALS
                     IITPYFVTPTQQELILHYKTIANSVNLPIIMYNMPSKTGINIEPESVRELSKIKNIVG
                     IKDSSGKLDNMKAYIEATKNENFSVFSGSDSLILDSLKAGSQGAVAATTNFLTEIGIS
                     IYENFMKGDLEEAQKAQSSIEELRRILKLGTIPSVMKKTIVLNGINVGTARLPVTEPT
                     GEVLEEIKRVVENYRTILNKSSENR"
     gene            complement(84688..85287)
                     /locus_tag="KR294_000080"
     CDS             complement(84688..85287)
                     /locus_tag="KR294_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBH0238203.1"
                     /translation="MENTLSEFLDNISNELSEFIASIDETSINKACELILEAEKNHGR
                     VHVTGIGKPGHVSGYISSLLSSTGTSAYILHGTEAVHGSSGQVVEGDVVIAISNSGET
                     QELKATLKTLKVNGAKIIGVSGNESSFLKNISDIFLFAGVKQEGDCLNKAPRASILAE
                     TIILQSLSVVLQYAKGLNTQQYLKWHPAGSLGKSIREGI"
     gene            complement(85345..86616)
                     /locus_tag="KR294_000081"
     CDS             complement(85345..86616)
                     /locus_tag="KR294_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HBH0238204.1"
                     /translation="MEFIISLLSTPAVLLGVVACIGLILQKKSAVEVFTGSSKTLIGF
                     LIFGIGASAMTGALQNFNKLFQHGFGITGVIASPEAATALAQGTYGFAVSCTLILGFI
                     LNLVFARITKFKNIFFTTGHSLFFSCVLVLIMKAHGFDNTITILIGGTILGFMSAALP
                     QFCQPFMRELTGGDEQAIGHFNMIGYGLSGYIGRLFSKHKDDTTETIEFPKWLSIFRD
                     FLMGLSIVMLILFYIATLKAGQAFTQEIAGSTHWLVFPLIEAFTFVAGMSILMSGVRM
                     FLAEITAAFVIISEKYIPGSRPALDVPTVFPYAPNAVIIGFISAYAAGLLAIAIMASF
                     PSIFPVVIIPAAHICFFSGGTAAIFGNTSGGWRGAIAGSFVVGLLLAFLPVILYPVYG
                     TLGIEGATFPNIDYNVVGSILHNILQFIKPI"
     gene            complement(86643..86930)
                     /locus_tag="KR294_000082"
     CDS             complement(86643..86930)
                     /locus_tag="KR294_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH0238205.1"
                     /translation="MYKILIACRAGVGSSLMLKIKTQQIIKENNFPIEVEHGSLDSLN
                     GFNGDAVETLIDVAEELKNKNLKFDIIGIHNIVDRNEIKTALEKFLASKEG"
     gene            complement(86945..89032)
                     /locus_tag="KR294_000083"
     CDS             complement(86945..89032)
                     /locus_tag="KR294_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBH0238206.1"
                     /translation="MVVDKEIVSILQILLNSTLITTNGLQEESNSSKRQITYRINKIN
                     DMLKVKNVPLICLRADKDIIVRKETKKAIKEILEKNYSKNTYYFSKTERLLYMYLMLF
                     INMEDISINHFINSIKVSRSTVNLDFKDLIPELEKKNIKVKNNRINGYYIVGNEMEIR
                     RVLIKNIIETLSNEKSSRVFDIFIKEYNLDSFEEAKKIILKLIKKYEITFVEDRLIEF
                     IYIFIFLKARMYSTRIVTQENVDIPNISVMSSMKEYKFAKELLEVYGSEDKIKPHNIM
                     YISAWILGISVGNYEEDTEDKDVISKIVNKMMTKFGYLSGVYYISQEKIFKQLYSHFR
                     PAYYRLLFKLPIYNPICEKVKEEYKLVYRIVSNAMKEFCGLFGEEIQEEELAYLTMHF
                     ATLFSNKKEFDGFRKRIALIVCSNGVGSSAILHAELTNLFPDLHFIPMSESVGLENIS
                     EPVDIVFTTNYNAEGLKTDVPVIKVSPVMTTKEKYKITREVYIQLGDIFLRQPKIDEV
                     MDIIKKYANVTSESILSSELLAYFTQIENFTSKEGEGPMLSEITNETLVKIKVKAKNW
                     EEAIRQSASVLVENNKVTEGYVDAMINSAKASGPYIVITKHVALPHARPEAGSKEIAI
                     GIATLDSPIEFGNNENDPVKYVFCLSAIDNNSHLRAMSELVELLEEDEFFKVLDSAKE
                     AKEIIDFIKTHEL"
     gene            complement(89447..89968)
                     /locus_tag="KR294_000084"
     CDS             complement(89447..89968)
                     /locus_tag="KR294_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003374619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBH0238207.1"
                     /translation="MVLLIVDAQKLITNERLYKFNEFVVNVENLIDTARKNNIEVIYV
                     RHDDGVENELTKGKNGFEIYEKFKPCNGEKIFDKKVNSAFKETGLLEYLTNNGEKDII
                     IAGLQTDYCIDATIKCGFEHGFNIIVPAYSNTTVDNFFMSAEQSYKYYNEFIWNERYA
                     KCISLEETLRKMK"
     gene            complement(90030..90836)
                     /locus_tag="KR294_000085"
     CDS             complement(90030..90836)
                     /locus_tag="KR294_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBH0238208.1"
                     /translation="MRTEKSLKRPIASFIILTNIIFLPLFLLVVVTIMLKLPTVISDI
                     ALCISAWSSTFAFMILFKKIYPGKKFLVHVKDRFRNKLKFSTVSIIISIQVLIAVVVI
                     FILASKNHGIMPNFTVSSWGAFIYLFLKNLFAGSLGEELGWRGFVQNHLQKRHSPLKA
                     SITVGFWWGMWHLPIWFTTGFKGLDLIKYIIFFMIAIISISIIMTTFYNLNKTLIIPI
                     AIHQLFNFLIGIINEDLIELINYYAMLYLIFAIALIVINPGNVLYKNIRE"
     gene            complement(90940..91734)
                     /locus_tag="KR294_000086"
     CDS             complement(90940..91734)
                     /locus_tag="KR294_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH0238209.1"
                     /translation="MYTIGQVSKFLGISRDTLKFYEDKGLVNPKKNDENGYRIYNQVD
                     IYDIATINFYREIDIEIKKIQEIRKSKSINNLELLLEEKEQIILKEIEYKKLLLKKVQ
                     LVKEDCDKIKTYFGKYTIKEMKPLEVKGKIKHVTNYEEYEALKENTNNLKKAVTLTDL
                     RRVINFNEEGIIEEKFIIVREVDDYNKIIEGEVLSHPNCIYTIIEDGRWSTGGENIDN
                     KVEDRLREIAIENECELLGIVYVNILLTTYEEGIERIFLEIYAPIK"
     gene            complement(92268..93122)
                     /locus_tag="KR294_000087"
     CDS             complement(92268..93122)
                     /locus_tag="KR294_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA hydrolase"
                     /protein_id="HBH0238210.1"
                     /translation="MAMGFEFKIMRSLIYVGLAKEEYRPKLMDWLYRHHIPDSISTFG
                     PYCTKYAFYQAYPTPNEGERFGARKMQLTEHYWLVDEHMPEMANRIMTEYMPMDVLRW
                     QGCIPDVENKRVHENAESGDAGRAVGGDNGCPPFIFAFVPINWEEDFRGKGRTVQDGP
                     NYRWQFMIKYPDGISKEEGEKWFYDEVVPYFTNCCYVNRFVSSKIMINYGATAFDRVS
                     ELWFEGEEEWYKAVVEETKSFIKKPEWAQEEEFPYLKPQFNIASVFLGDIATMDAYSQ
                     YRGYIPMR"
     gene            complement(93154..93666)
                     /locus_tag="KR294_000088"
     CDS             complement(93154..93666)
                     /locus_tag="KR294_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1097 domain-containing protein"
                     /protein_id="HBH0238211.1"
                     /translation="MDRKKKEILTLSMGIALLPPLWAVLAPYIGIKTGAVALICAGLY
                     VTNGNKQEDGLKIMFGFWCGDLWAVLAILIMGYMNFNQNLELFLTLSILGFFAVVIAS
                     LFEKIIFLPSWLCGWAIGLTIMTGENIINLQDICIQIAVAMAVGVWYVGAGVDLFTIY
                     ILSKDRKKGN"
     gene            complement(93659..93883)
                     /locus_tag="KR294_000089"
     CDS             complement(93659..93883)
                     /locus_tag="KR294_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0238212.1"
                     /translation="MNEKPSFKQIEVILAVIFLVLTYYKVRLTPAFIVIFIPLYLSYF
                     AVSMIVNQIAIKLLEIRQAREATNYNIGNG"
     gene            complement(93943..94896)
                     /locus_tag="KR294_000090"
     CDS             complement(93943..94896)
                     /locus_tag="KR294_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HBH0238213.1"
                     /translation="MKILGISFGTKNGNNDTMCKVALKGAKEAGAEVEFIQMSSINIK
                     HCTGCCACVKTLLSGKGSMCVLKDDFEWLLDKMKDADGIVVSDPIFEEGASGLFHTIM
                     DRFGPRADRGNNIIGTKVAEAIGGKIPDSRMLNDKVISFMGIGGSDWGTRVQCEHAML
                     ALIPMWKVIDNAWFPWAKELVMDDTRLVQVHQIGLNIVEAAKDFEKASYQGEEGVCPH
                     CHNRLFYLEPGTKKAICALCGIVGELDTISGKTIFSFPEEQLGHAHDTLPGKFIHGDD
                     IKKMEGHYAEVRKTQEFKERKTSYNFIETLTKEKQAGVSLG"
     gene            complement(94924..96312)
                     /locus_tag="KR294_000091"
     CDS             complement(94924..96312)
                     /locus_tag="KR294_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0238214.1"
                     /translation="MEDKFYAKGNGNNGYIKNLEVCSFNNLDGTCGMFQMALYKRDEK
                     YYLYGCCFGGNKKNGVMISDITDPYNPQFIKHFQMLDPKEYPTTTTPKIQIADDLMIV
                     AMSCGSGPGALVDQAKLANIKCEAGIRIYSLKEDPLNPKFLGYWDCGLKHVMGVHRFM
                     YNGGRYVHLSSDCVGFEGLIYRVIDIINPTNPVEIGKWWRPDQYADGYPNRTFDAGAP
                     HCPEFMDKGWLHGPPFVRDGKAYCGYGGAGLVVLDVEDLTRPRCLGELPFMPAFSSRL
                     AGARTHTALPLPGRDLVVVQNEGERFQFFKPDNITDVQAMNNIHMVDVSDPTKPTLIA
                     QFPYPEVPKDFPYPNFNVAGLGKPGPFGPHNLHEPMDNKPWLEQRGDRVYCCYFHAGL
                     RVYDVSDPYYIKELAYFIPPNPNKTPEESYFPGFPGPRLAVTEDLIVDDRGYIIIDAL
                     DDGFYILKMKED"
     gene            96585..97465
                     /locus_tag="KR294_000092"
                     /pseudo
     CDS             96585..97465
                     /locus_tag="KR294_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429230.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
     gene            complement(97653..98645)
                     /locus_tag="KR294_000093"
     CDS             complement(97653..98645)
                     /locus_tag="KR294_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HBH0238215.1"
                     /translation="MNILAFGEIMMRLSVPDYKFLTQTNELNYIITGTGLNILSGLKN
                     FGYNTYMLTKLPNNNVGKASSANIRKLGVKDDFITYGGNHIGVYFLENGYGERPSEVT
                     YLNRLNSSFCESKLQDYDIDKCLEEMDIVLICGIAMQLTDSIKEIALELARKSYEKGI
                     KVFFDFNFRQSLNPERTYDDLVNDYKKILPYCHGLFASYRDINKILNIDSLNIKSSSE
                     LIKKEYDIGIVAGTMRRFDDMNNRFIKGYISNDDGYFESREYKLEIYDRVGAGDGYVA
                     GIIYSYLENMKSEDIVEFGVASSVLAHTTYGDNSLVSTGHVLRLMNNEKIDILR"
     gene            complement(98650..99390)
                     /locus_tag="KR294_000094"
     CDS             complement(98650..99390)
                     /locus_tag="KR294_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KDGP aldolase family protein"
                     /protein_id="HBH0238216.1"
                     /translation="MNCIPQYYKNRVCLNVLAGSIKNAKEVYDACDGYVLIGVLSKNY
                     STVEAAIEDMKKYSKEIDNAISVGLGAGDPNQSNMVSQISKELQPQHINQVFTGVATS
                     RALLGQNDSIINGLVSPTGKPGFVKISTGPLSSKEKDGIVPIETAIAMMKDMGGSSIK
                     FFPMGGLKTKDEYIEVAKACAKHNFYLEPTGGIDLDNFKEIVQIALDAGVEKVIPHVY
                     TSIIDKETGETKVEDIGVLYKIMKELLG"
     gene            complement(99455..100564)
                     /locus_tag="KR294_000095"
     CDS             complement(99455..100564)
                     /locus_tag="KR294_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DgaE family pyridoxal phosphate-dependent
                     ammonia lyase"
                     /protein_id="HBH0238217.1"
                     /translation="MSSIFEKYSVRRVINASGKMTILGVSTVDKEVIEAIGEGCKNFF
                     IIEELINKTGEYIANLLGCESALIVSSASAGIAQSVGAMIAKDDMSLVYNVNNPKKQV
                     KREIIIPKGHNVDYGVPVEVMIRLGGGEVVEAGYANMCNKEHIIREINENTAAIMYIK
                     SHHCVQKSMLSVLDAVQVAKEYNLPLIVDAAAEEDLNVYYELGADLVIYSGAKAIEGP
                     SSGLVIGKKKYIDNVKLQSKGIGRAMKIGKENIVGLTCAIERYISNDKVTLKEMEDKL
                     NPFIDKINTIKGVSASITRDSAGREILRGEIDFNEDIINKSTQQIINELRSGEIAIYT
                     RDYKANEGKIEIDIRSVTGSDLDTIYNRIKNIVES"
     gene            complement(100582..101715)
                     /locus_tag="KR294_000096"
     CDS             complement(100582..101715)
                     /locus_tag="KR294_000096"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase/deacetylase family
                     metallohydrolase"
                     /protein_id="HBH0238218.1"
                     /translation="MKIDILIKGGKTVDKSIIDIAILDDKIIEVKNQIDDSKYQANQI
                     INLDGEKFISAGWIDIHTHCYERLDLYKDYPDEVGIKSGVTTVVDAGTTGALDIGKFY
                     EDTKKYKTNVYALINIAKQGITSQDELSSMMNIDEYELKRAVKKYKDFVVGIKARMSK
                     SVVISNDVEPLKVAKRIKNELNLPMMVHFGSSPPTIEDIFDYMEKGDILTHIYNGKPN
                     GILRGNEVKKEIIEARERGIILDVGHGTESFSMDIAMKSKDAGIFPDTISTDIYIKNR
                     INGPVYNLSTTMEKFIYMGYSLEDIIDKVTKNAADAISLKNKGLIKEGYDADLTIFDV
                     VNEEKELQDSLNKSVITSTSIKPRAVVVNGEYLNIGKSIGENE"
     gene            complement(101717..102811)
                     /locus_tag="KR294_000097"
     CDS             complement(101717..102811)
                     /locus_tag="KR294_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBH0238219.1"
                     /translation="MERRLGISVYPEHSNMEDDKAYIKMASKYGFKRIFMCMLSITRP
                     KEEVKKHFKEIITYARELGFEVILDIAPNIFDILQISYDDLTFFSELNASGIRLDYGY
                     DGSKEAMISFNPYDLKVELNMSNDVAYLDNIITYKPNVNNIYGCHNFYPQRGTGLPYD
                     FFVRCSNRFKKYGIRTAAFVNSKYATIGPWNINDGLCTLEMHRNLDIATATKHLFATG
                     LIDDVIVGNAYASEDELKRMSEVNKYQVVFNVVTEEKTSEVEKTIMANEQHFRRGDIT
                     NQVARSTEVRKKYAKENFPKHDNTTIFKRGDVVIGNDDFGKYKGELQLILQDCADERK
                     NKVGRIKEDEIMLLDFIEPWSKFKLILEGE"
     gene            complement(102948..104249)
                     /locus_tag="KR294_000098"
     CDS             complement(102948..104249)
                     /locus_tag="KR294_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH0238220.1"
                     /translation="MEKFASFLERKIMPVAAKISNQRHMRAVRAGIIATLPLTIVGSF
                     FTILLNIPIDAYMDFIAPFKAILDIPFRYTVGFLSLYATFGIASSLAKSYDLDTTGVG
                     MLAVMAFLVSTIVPTQVVEPVGGVIEAGRWMDMAKLNSPSLFGAIVTSLITVEIYRFM
                     KEKNITIKMPAGVPVEVSNSFTALLPTAVILMLFWVIRHILGFDISVALSAMLSPLKG
                     FLSGNSLGGGLLTVFLITLFWVLGIHGPAIMGPVIRPIWDMSIAENITAFTEGVSAHA
                     MPNIFTEQFLQWYVWIGGAGATLALVVMFMFSKSQYLKSLGRLGFLPGLFNINEPIIF
                     GAPIVMNPILGIPFIIGPIIMTILSYVLTITGVIPMMVARLPFAMPAPIAAVMSTNWS
                     ILAGILVLINFVISFAVYYPFFKVFEKQQLQREQEEMSENL"
     gene            complement(104473..105174)
                     /locus_tag="KR294_000099"
     CDS             complement(104473..105174)
                     /locus_tag="KR294_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH0238221.1"
                     /translation="MLRNQPLYIQVVDILKQKILNNEYKIDENIPTERELEQEFGVSK
                     ITIRKAIEILESEGYVEKKSGKGTKVISNSLFNKLSKAESFSSILLSKGHKLSKKTIS
                     IEKIINDTNSQVFSIFGEKCSKITRMYYLDSKPYIFFTHYIPFDENLTVESFNNESSL
                     YMYLYRRNINITRFEDEFFIEESELEVSKALNLAKDILLGRKRKTYDENDNIVELSFA
                     RYNTEVQNYVIKYEI"
     gene            complement(105387..105704)
                     /locus_tag="KR294_000100"
     CDS             complement(105387..105704)
                     /locus_tag="KR294_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBH0238222.1"
                     /translation="MDEKTIEISFNIIGYAGEGKGLAFEAIKEAKNGNIEKAKELLKE
                     SREVINKAHRYQTELIQNEASGNRTEISVILIHAQDHLMNGMNFQQLAEEIVDLHLKL
                     QDK"
     gene            complement(105752..106063)
                     /locus_tag="KR294_000101"
     CDS             complement(105752..106063)
                     /locus_tag="KR294_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH0238223.1"
                     /translation="MIKIMLACSAGMSTSLLVTKMESAAKENGIESQIWAIPESTIQN
                     EIEKCDVLLLGPQVRYVLPKAQEIAKPYNIPVEVINMMHYGTVNGEAVLNRAIELNNT
                     K"
     gene            complement(106212..106691)
                     /gene="rlmH"
                     /locus_tag="KR294_000102"
     CDS             complement(106212..106691)
                     /gene="rlmH"
                     /locus_tag="KR294_000102"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HBH0238224.1"
                     /translation="MNISIVVVGKIKEKYLKLGIDEFKKRLSKYCKLEIIELDDEKAP
                     ENLSVKEMEIIKDKEGKKILGKIKHNSYVIALAIDGKGLSSEELAKTMSDLAVRGNSS
                     LCFIIGGSLGLSDEVLGRADYRLSFSKMTFPHQMMRLILLEQIYRAYRINNGEPYHK"
     gene            complement(106759..108861)
                     /locus_tag="KR294_000103"
     CDS             complement(106759..108861)
                     /locus_tag="KR294_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC/EAL
                     domain-containing protein"
                     /protein_id="HBH0238225.1"
                     /translation="MLKRNFENVEDNKILYSIKQGMILAIPAIMTGSTALVILNLPIK
                     AYQEYLSGLFNGEVTNILNFINDSTLGIISLIILLTISYSYGKIYGSKYTVLVPIVAM
                     CSFLVFSHGNELNSYIEIFKTKWLFTSIIVSMTSSVLFVKLTESFVTSVKFHTEGADA
                     DFNMVVSAIVPFIIVVFLFSIFRVVMISLIGSSNFQDIFYNLFSNVFNKMGTNLMSAL
                     LFIFLMHFMWFFGIHGSNVLDTVAKNLFENSMAININLVNNNQLPTEIFTKTFFDTMV
                     LLGGCGSLLCLVIAIFLSEKRINVRKLAKIASIPALFNINEMLVFGIPIVFNYIMFVP
                     FVITPIILTVTSYVAMSTGIVPCTVSAVEWTSPIFLSGYMSTGSIRGSLLQVFNLCVG
                     VMIYIPFIKMSQNRYTYMFKNNIENLTNLLKRYELTGEQPNLLNHNGKIGSISKMLAS
                     DLKFAMKRGEIELFYQPQVNYNGNVVGAEGLLRWKHSIGGFIYPPLVIILAKEEGFLD
                     ELGEYIINKACIDLKKSEKLLRNPVKFSVNISPDQLDDPKLPEQIKNIISSNDINPNM
                     LGIEITEQIALSGSQIIIERINAIHNLGIKLIMDDFGMGHSSLIYLQNNNFDIVKLDG
                     SLVKEILTNKRSSEIIMTIVNLSKNLDFDIVVEYVENIDQRDKLYGLGCEIYQGYYYS
                     KAIPFEEFVEYANQEREI"
     gene            complement(108874..109671)
                     /locus_tag="KR294_000104"
     CDS             complement(108874..109671)
                     /locus_tag="KR294_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBH0238226.1"
                     /translation="MLKYCSVGSGSSGNCHYIGYKNTNILVDAGLSGKRITTGLKDIG
                     VDADKLKGIFITHEHVDHIKGAGILSRKFDIPVFANIKTWCSMKDKLGDIKDKNMKVF
                     ENDKTYSLGDIIVRPFSIEHDASDPVGYNFYTESDEKMSIATDIGCITQNIKKHLYKS
                     KLVVLESNYDPNMLMMGSYTYALKKRVMSSTGHLSNEDAANFCVELINEGTESILLAH
                     LSKENNFPELAYETSKGVLASNDIVVGQDVKLDVLSRNDVSNVYEMK"
     gene            complement(109773..111236)
                     /locus_tag="KR294_000105"
     CDS             complement(109773..111236)
                     /locus_tag="KR294_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HBH0238227.1"
                     /translation="MVIKFNQKVRRTLSVAILFMVLIIGCFIEKDDSLETYKEKTNSK
                     INQYNMDVIFDDETKRLMCNQNVDYINNTKSNIDKIYFHIYPNAFSKKDFAPFEKSEM
                     TRAYPNGFNEGYIDIKNILNNNSKMEYKIKGDKNDILEIELGKELKPNERMSLDIKYN
                     VKIPNSIGRFGYGENTINVTNWFPIACVNDERGWNLKSYETIGDPFYSETSDFHVKLL
                     IPNKYKIAHTGKLIDDKHDNKKMLYEIEAENVRDFAFILSSKFDVNKVDSKGVAINTY
                     NLNKKLSKKATEVAKDSINIFSELFGKYPYKEFSVVASDFFIGGMEYPMLVMIDQSLY
                     NEKNEFLLEYVIAHETAHQWWYSAVGNDEISEPWLDEALTEYSTIVYFEQKYGKDMAN
                     KLIKTMEIQTKSYLSENIFKPANEYKNSTEYSLNVYTKGAIAFNEIRKEVGDKVFFET
                     LNEYYNKYKHKNANGRAFVELWNSKGVDINKIISECK"
     gene            111361..112419
                     /locus_tag="KR294_000106"
     CDS             111361..112419
                     /locus_tag="KR294_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HBH0238228.1"
                     /translation="MFFKESNEIDLGEITIPNIFIDIFMPMADGLYVKVYLLGYRQAC
                     DITSNPKFDNNSIAKNLNIPLSDVLSAWKFWEEKKIIKIHDNEEYDNFNYSIEFLDLK
                     NFYIENILSNNSSIKSNTDKVVSTSENPSIRKMFNSINKIVGRYLDPSEKMSIMDIMN
                     KYNMSPDMILCAYEYVKDKTGTSKPVKYIEGIIRNWYDSNLYTPKDVEESFLVRSERY
                     ILYKTIFNELGFSRQPSKSEKELMDTWFDKFNMDIDLIINACSKSKNISNPSISYING
                     IIKNWNEKNIKNLNDLKQKEEERIVKENINKKQINTTQNNNTYKKTKFHNFNETFTQY
                     TSDELDEIIKKSQKEKFK"
     gene            112428..113420
                     /locus_tag="KR294_000107"
     CDS             112428..113420
                     /locus_tag="KR294_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH0238229.1"
                     /translation="MNEDKIRKILAKYAKRRDDNELLLEHRKNEVYNRIPEIKSIDDE
                     ISKIGLSLAKIVLLNPKSKDEIVKKTKENIESLKVKKERLLAESNIPLDYLEIKFQCI
                     SCKDKGFLPNGEKCSCLKQEIVNEAYKMSNLDRILSQENFSNFNLNIFSPKKGSDGEI
                     SPRENMLNNLSICENFVHDFKKDNSENLLFYGSTGLGKTYMCNCIAKELLDKGNVVIY
                     QTSFRILDILEDYKFRRDTNNQISEDNYKNLFDCDLLIIDDLGTELNNSFTSGEIFNI
                     VNTRLVAGKKIIISTNLTPSQIGNTYTQRTLSRILDKFRILEFTGDDLRWERFK"
     gene            complement(113803..113877)
                     /locus_tag="KR294_000108"
     tRNA            complement(113803..113877)
                     /locus_tag="KR294_000108"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(113843..113845),aa:Thr,seq:tgt)
     gene            complement(113911..113986)
                     /locus_tag="KR294_000109"
     tRNA            complement(113911..113986)
                     /locus_tag="KR294_000109"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(113951..113953),aa:Val,seq:tac)
     gene            complement(113991..114065)
                     /locus_tag="KR294_000110"
     tRNA            complement(113991..114065)
                     /locus_tag="KR294_000110"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(114030..114032),aa:Glu,seq:ttc)
     gene            complement(114072..114147)
                     /locus_tag="KR294_000111"
     tRNA            complement(114072..114147)
                     /locus_tag="KR294_000111"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(114112..114114),aa:Lys,seq:ttt)
     gene            complement(114473..115762)
                     /locus_tag="KR294_000112"
     CDS             complement(114473..115762)
                     /locus_tag="KR294_000112"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HBH0238230.1"
                     /translation="MKTVAIVGSQWGDEGKGKVIDYLATQADVVVRGQGGNNAGHTLV
                     VEGKKYALHLIPSGVLNPNTVNIIGNGIVFDPKGFLEELEMFKTDNISTENIKISDRA
                     HVIFPYHKELDALSEEARGDLKIGTTKKGIGPCYMDKTERSGIRICDLMDKDKFAIKL
                     KAQIDAKNEIVKNIYGKEELFDFETIYNEYLGYAEQIRKYVADTSVIVYDAVRAGKKV
                     LFEGAQGTLLDLDLGTYPFVTSSHPTSGGFAIGAGIGPNMIKDVVGIVKAYTTRVGEG
                     PFVTEQINETGDKIREQGHEFGVTTGRPRRCGWFDAVIVKYAARVNGLTSISFMLLDV
                     LTGFDKIKVCTSYKMGDKIITDFPASLDDLAKCEPVYEELDGWNEDITQIDNFDDLPE
                     NAKKYVAKIEELVGVSVDMVSVGPNRAQTIIRRNIFA"
     gene            complement(115844..116152)
                     /locus_tag="KR294_000113"
     CDS             complement(115844..116152)
                     /locus_tag="KR294_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0238231.1"
                     /translation="MEKISLKYIYPNIIKVLDEINLFRVIDNNLRESIVVYANNVDNQ
                     YHINMTNTNFGNIINICKLEKLLDVDKFMEKVIKYEKEIIEKEEFSKIEEYMLNIGEY
                     "
     gene            complement(116357..117685)
                     /gene="dnaB"
                     /locus_tag="KR294_000114"
     CDS             complement(116357..117685)
                     /gene="dnaB"
                     /locus_tag="KR294_000114"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HBH0238232.1"
                     /translation="MEDMTRIPPHSVESEQSILGSILLDKDAIITVTETIKPDDFYKE
                     AHKIIYECMITLSNKGEPIDLITLTEELRKQGHLNDIGGISYITSLSTIVPTTSNVKY
                     YADIVKEKSVLRKLIKASNEIINLGYSGATKIEDVLEQAEKSIFDISQEKTSDDFKSI
                     NLVLMDAYDMIEKLYTNKSDVTGITTGFKDLNKKINGLQRTDLILIAARPAMGKTAFS
                     LNLVQNAALKGDASVAVFSLEMSKEQLVQRMLSSQSSVELKKIKTGTLNDNDWPRIID
                     AMAVLSDAKIHIDDTPGIKISELRSKCRKLKIEKGLDLVLIDYLQLMEGEGNNESRQQ
                     EISKISRSLKILAKELNCPVVALSQLSRAPEQRADHRPMLSDLRESGAIEQDADIVMF
                     LYRDEYYHADSESKNIGEVIIAKNRHGETGSVELVWLGEVQRFGDKLRDL"
     gene            complement(117704..118153)
                     /locus_tag="KR294_000115"
     CDS             complement(117704..118153)
                     /locus_tag="KR294_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HBH0238233.1"
                     /translation="MKVILLKDVKGTGKKGEMKEVSDGYARNFLFPKKMAVQADSVAI
                     KELNEKNKSKEIKAQKEYEEAVLLGKQMEEINIEIYSKAGEGGRLFGSITSKEIAEQL
                     KKQKDIDVDKRKILLDEPIRSLGSTFVEIKIHQKVTTKIRVDVKEKQ"
     gene            complement(118154..120148)
                     /locus_tag="KR294_000116"
     CDS             complement(118154..120148)
                     /locus_tag="KR294_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HBH0238234.1"
                     /translation="MSNKQTFKLNMPEINLYIIVIGISSIILLYYNLYVGCLFFCIFV
                     YMVFHNWRTTNIRRHEWTEYIQNLSLDIDETTKKAIINLPIPLCILEFDGNISWYNGK
                     FYDMIGQKDLLDKNIEDIVKNLNLRKVLNENKEMYTEINYKEKEYTIIYNVIKNDQEK
                     NPKYLMILYWIDKTEYLKVKQNYDDEKNAMMLIQVDGYDEVLKSAAEDKRALINVEVE
                     KILSALELNSNGALRRTSKDKFFLVMHKKELKKLEAEKFSILDTIRHIDYGNNLPVTI
                     SIGIGIDGDTLNENLKLATGALDLALGRGGDQAVVKTKDKFVFYGGKSKAVEKKTKVK
                     SRLIGHALREVIQQSDQVYIMGHKYPDMDAMGAAVGVYDICKSCNKTANIVLQSVNES
                     IEIFINKINENNYYKKLFIGKEEAIDNCTKNTLVVVVDTHRPNYTECEELLKLSEKVV
                     VIDHHRRGVEFINDAVLLFHEIYVSSTCEMVTELVQYMDEDVTINKLTAEGLLAGISL
                     DTKNFAFKTGVRTFEAASYLRKVGADTIEVKKFFNSDVKDFIIKAEIIQSTKIINNRI
                     CLAYSSTEIDSINVIIAQTADELLNIKEVEASFVLGEKDDTIFISARSLGQINVHVLM
                     EKLGGGGHIDIAGAQLKNVSLKEAYKMVNKIIEEYLEEEE"
     gene            complement(120159..121115)
                     /locus_tag="KR294_000117"
     CDS             complement(120159..121115)
                     /locus_tag="KR294_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YybS family protein"
                     /protein_id="HBH0238235.1"
                     /translation="MNNKIRLSKAMSIIVLAIIIALVIAYIPMLGIFSMLAAVPYVII
                     GAITDRKYSLISILVTFCVLILFADISYALNICIMYSLPGIVIGKMLKRSFEQEDSNK
                     FEPIYGGTIIFVLSMLVYFFVLKTFLNVNLLDEVSKMISEIVNIQKNSFSATELKVFD
                     KMKPDEIVSYFTNMLPMMLFLQGLLSAFVTYYLSVFFIKRITKMNIRFPKFADFYLPG
                     NAILTTFLLYLLVLFIQIIGSKLYTELIMTNLQLVFNLMFVIQGIAVCIYFLKKWIRQ
                     GPNKIMFFSGIILCLFGFMGISFVGMVDSIIDFRKVRSYKST"
     gene            complement(121123..121443)
                     /locus_tag="KR294_000118"
     CDS             complement(121123..121443)
                     /locus_tag="KR294_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HBH0238236.1"
                     /translation="MKIDKGSEITRNIKIIEWMKTEILMSVSDLFNLLFKGVKPLDEA
                     IQDTLANIIMITYLLAKRLGISFRDVDYKVKEKIKIGIDEDHSVERWYGDLSNLKKHM
                     DNRE"
     gene            complement(121586..121813)
                     /locus_tag="KR294_000119"
     CDS             complement(121586..121813)
                     /locus_tag="KR294_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HBH0238237.1"
                     /translation="MMNKKRRKKKRVCQFCADKNAKIDYKSTQRLQKYITERGKILPR
                     RISGTCAKHQRELTVAIKRARNIALLPYTLD"
     gene            complement(121832..122266)
                     /gene="ssb"
                     /locus_tag="KR294_000120"
     CDS             complement(121832..122266)
                     /gene="ssb"
                     /locus_tag="KR294_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBH0238238.1"
                     /translation="MNQVVLVGRLTRDPELRYIPGTGTPVASFTIAIDRDYVKKDGSK
                     ETDFIPVEVMGKSAEFCANYITKGRLVALQGSIRVDNYQTQSGEKRTFTKVSTRSVQA
                     LDSKNKSENSYRESAPAFEPSFEPQGLDPQGFQAIDDDDIPF"
     gene            complement(122303..122581)
                     /locus_tag="KR294_000121"
     CDS             complement(122303..122581)
                     /locus_tag="KR294_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HBH0238239.1"
                     /translation="MRNYELVYVVKPNSDEEVREAILNKVKEVVATDGEIVKVDTWGT
                     KKLAYPIAKFTEGFYVLVNFKSAVDVPKEIDRNLKINENVIRHMIVVA"
     gene            complement(122795..123991)
                     /locus_tag="KR294_000122"
     CDS             complement(122795..123991)
                     /locus_tag="KR294_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBH0238240.1"
                     /translation="MAVKYAKRMQGLQGSEIRELLKLTQQPQIISFAGGMPAPELFPV
                     EEMKKVSVAVLEENGRSAMQYTTTEGYEPLREKIAARMNDKNKTNVNKDDILVTSGSQ
                     QGLDFAGKVFIDEGDVILCESPSYIGAINAFKSYQPKFIDVPTDSDGMIMEELEKILE
                     TTDRIKMIYVIPDFQNPTGRTWPLERRKKFMEIVNKFEIPVIEDNPYGDLRFEGETLP
                     SLKSMDTKGLVIFLGTFSKIFCPGYRLGWTCASPEILSKFNFAKQGADLQASTISQME
                     VSKFMDMYDLDAHVDKIKAVYVKRRDVMLKTMEEEFPEGLVFTHPEGGLFTWVELPSN
                     LNAKELMPKCLDKNVAYVAGGGFFPNGGRENTFRLNYSNMPEEKIIEGIKNIAAVLKE
                     AMGVEA"
     gene            complement(124094..124279)
                     /locus_tag="KR294_000123"
     CDS             complement(124094..124279)
                     /locus_tag="KR294_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HBH0238241.1"
                     /translation="MPMDLKIGDIVELKKQHACGCKEFEIIRTGMDIKIKCTKCSRLI
                     MLDRETLEKRVKKLIKK"
     gene            complement(124294..124557)
                     /locus_tag="KR294_000124"
     CDS             complement(124294..124557)
                     /locus_tag="KR294_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3343 domain-containing protein"
                     /protein_id="HBH0238242.1"
                     /translation="MNQMYIVSFNSTHHAIRSEKLFGENSLKVMALPTPREITASCGI
                     SIKFSFEDMEKIKTILVENNVDIKGIYCISKLENGSKEVEKLD"
     gene            complement(124630..125232)
                     /gene="yedF"
                     /locus_tag="KR294_000125"
     CDS             complement(124630..125232)
                     /gene="yedF"
                     /locus_tag="KR294_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase-like selenium metabolism
                     protein YedF"
                     /protein_id="HBH0238243.1"
                     /translation="MSIKIDARGLACPKPVINTKRELDNLEEGVVVTIVDNETAKENI
                     LKLAKSLSCEANIVDEKENFISIEIRKGKNILDKQNVVDNKESELDNTCIFISSDKMG
                     LGNDELGKVLIKGFIYTLTESKPYPKYVLLVNGGVKLSAENEETIENLKILENMGVEV
                     LSCGTCLDYYNLKDKLQVGTVTNMYTIVETLKNASNTISI"
     gene            complement(125337..126629)
                     /locus_tag="KR294_000126"
     CDS             complement(125337..126629)
                     /locus_tag="KR294_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBH0238244.1"
                     /translation="MEILSLGEKIKKLRKEKNMTLKELAGDRITAAQISHIERDKSHT
                     SYELLEYLGDKLDVSVEYLLETKEMQSKKITDNLILQSEIYIKENELNKAEDQIKEVL
                     DICKRYDLMENYGRCNFLMANINLKKSNYNDAIENFEKALYFFIKNSDSENILKCYLN
                     IGKIYMQEDFYKGAISHFNFAEEILSESKFEDVNIHKELYSKMAYCYIKLDNPNMSLK
                     YIEKINEIDNRNDRKEDVDILVLKANNMLEIGKYEESRDYFKKALKILESEDNKTGLA
                     NVYLTICDVYRKIGETDRVLEYSQKVYDIKKNDEDEYMMSGLFKIIEAYIDKEDYDLA
                     RKYCKIALASSIKNKNKFNEYKALRFYANMYKNQNEVTLAIEYLIKCIKIVSDLGNNR
                     ILANLYIDLGQLYSNISKEKELEYYQKGVFMYKNLEIM"
     gene            126889..127464
                     /locus_tag="KR294_000127"
     CDS             126889..127464
                     /locus_tag="KR294_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GerMN domain-containing protein"
                     /protein_id="HBH0238245.1"
                     /translation="MKNKKIMLVLSILSISIFAVGCTNAQNGSDSSKKETKSNTNVEQ
                     PKEENNTEKEVPNNKAKPTPKEETKAQSATIYSFDVDKTDLIENKVDLNKIDENTLFE
                     ELQKLKVVPESAKLNSFTTKDIDGVKTGILDVSSDFTKSNLGSDAETLMLDSVARTYI
                     KNMNVEQIKITVDGSNYESGHIVLEEGDYLK"
     gene            complement(127598..128740)
                     /locus_tag="KR294_000128"
     CDS             complement(127598..128740)
                     /locus_tag="KR294_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HBH0238246.1"
                     /translation="MIYLDNAATTYPKPERVYNAVLDCMKNYCANPGRAGHKLAMRAA
                     REIYDTRENIAKLFNVSNPMNIVFTSNATDSLNLAIKGVLQEGDHVITTSMEHNSVIR
                     PIKALEKRGIENTVVKCDYEGFLDYEDLEKSIKNNTKLIVTTHASNVCGTLIDIKKVG
                     EIAKKHNILFLVDASQTAGVYDIDVNECNIDMLAMPGHKCLFGPQGTGILYVREGLNL
                     NILKEGGTGSKSEEIVQPELFPDKYESGTHNTPGIAGLNQGILFIFERGINNIRQHEE
                     ELCQYMIDKLEEVPDIKIYGPKDSKKRASVIALNIGDMDSGEVTFLLDSDYNIATRSG
                     IHCSPLAHTTLGTLKQGAVRFSIGYFNTKDEIDKAVEALKKISKNK"
     gene            complement(128773..129636)
                     /locus_tag="KR294_000129"
     CDS             complement(128773..129636)
                     /locus_tag="KR294_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HBH0238247.1"
                     /translation="MENKSKRSNRLGRGLSALIPEIKGETSEKEIVNIDIDKIYPNEV
                     QPRKQFDEEKIKVLSDSIKNYGVLQPIVVKMDENNKYMIIAGERRFRASKLANKNQIP
                     AIIKDIDMKDIMEIALIENLQREDLNSIEEALAYKSLIEHYNVTQEEISEAVGKSRPH
                     ITNTLRLLNLGQDVIEMIDSGRITAGHGKALLRIADKDLQLQIAKKIEEEELSVREVE
                     NIAKKISENKQEEPKKSKPKDVFILDVEDKLRNIFGTKVNISKGKKKGKIEIEYYNDD
                     DLNSIVSMLLE"
     gene            complement(129638..130411)
                     /locus_tag="KR294_000130"
     CDS             complement(129638..130411)
                     /locus_tag="KR294_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBH0238248.1"
                     /translation="MGKVIAVFNQKGGVGKTTTNVNLSASLGTLGKKILVLDLDPQGN
                     TTSGYGINKNEVENTIYEIMLDGLHIKEAIISTEFENVDVVPSATELSGAEIELTSKT
                     NREYILKNSIKAVIDEYDYIFLDCPPSLGMLTINCLTAVDSVLIPIQCEYYALEGVSQ
                     LMETIKLVKSRLNADIEIQGVVLSMFDGRANLSIQVVEEVKKYFKGSVYTTLIPRNVR
                     LAEAPSHGKPVIYYDKRCRGSVAYLELAEEFIDLEEEEW"
     gene            complement(130546..131331)
                     /gene="noc"
                     /locus_tag="KR294_000131"
     CDS             complement(130546..131331)
                     /gene="noc"
                     /locus_tag="KR294_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid occlusion protein"
                     /protein_id="HBH0238249.1"
                     /translation="MEDKRVMEIPIEDVVPNPYQPRKIFSQVSLEELSNSIKVYGIIQ
                     PITVRAKDGKYELIAGERRLRAAKLAELKTIPAIINNMNDESSAVLALLENLQREDLN
                     FIEEAIGYENLIKEHAFTQQQLAEKLGKNQSTVANKLRILKLPNDIKMKLIENNLTER
                     HARAFLKLPSEDLMQSVLDKVIKNELTVKKTEKLIQDVLEETKVQEEPDKKQNIKGAM
                     SIRIYINTIKQAFDAISNTGIDAKYNEIDKGDYMEVVVKIPKK"
     gene            complement(131494..132213)
                     /gene="rsmG"
                     /locus_tag="KR294_000132"
     CDS             complement(131494..132213)
                     /gene="rsmG"
                     /locus_tag="KR294_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HBH0238250.1"
                     /translation="MNNIELLKNGIEGFNIDTNDSMLEKFKIYREILVEWNKKMNLTG
                     IEDEKEVYIKHFLDSISAVKNGYIKNGMSIIDVGTGAGFPGIPLKICLDSLELTLLDS
                     LNKRINFLEEVSRVLELDNITFIHGRAEDFGKNEDYREKYDVATARAVAGLPILMEFC
                     VPFVKVGGYFICLKGPNANLELEESQKAIDVLGLEYIEKIDVELPEVDLNHNILVFKK
                     VMETPVKYPRKAGKPAKNPIK"
     gene            complement(132206..134098)
                     /gene="mnmG"
                     /locus_tag="KR294_000133"
     CDS             complement(132206..134098)
                     /gene="mnmG"
                     /locus_tag="KR294_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012065747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HBH0238251.1"
                     /translation="MKFEAGKYDVIVVGAGHAGCEAALATARMGYKTLIITMSLDSIA
                     LMPCNPSIGGTGKGQLVKEIDALGGQMGLNIDKTYIQSRMLNTAKGPAVHSLRAQADK
                     FKYHEEMKKTLEDEPNLDIAMDEVVEILHEGNVVIGVGTKLGCSFKSKAVILATGVYL
                     NSKIYMGEVAFYEGPNALGYAKYLTDSLVELGLRMRRFKTGTPARVHRDSIDFSVMSL
                     QEGDEKVTPFSFMNENIEKKQEPCYLTRTTEETQKVILDNLKRSAMYSGVIESTGPRY
                     CPSIEDKVVRFSDKTSHQLFIEPEGLNTKEMYIQGISTSLPFEVQLDMYKTIKGLENC
                     KIMRPAYAIEYDCVDPTQLKISLEIKGVENLFSAGQFNGTSGYEEAAAQGLMAGINAV
                     RKIEGKEPFVLDRSEAYIGVLLDDLVTKGTNEPYRMMTSRAEYRLYLRQDNADMRLTQ
                     KGYDIGLVKKDRYERFLNKKAAVEKEFERLKNERVTPKEVNSLLEEKGATPIKVGISL
                     YEFLKRPEVTYELLEELGKGAGEDVSREVKEQCVIITKYEGYIEKQLKQIDQFKKLEN
                     KKLDEKINYSSIEGLRLEARQKLDDIKPISIGQASRISGVSPADISVLLIYLEQIRRT
                     RGGKGE"
     gene            complement(134196..135575)
                     /gene="mnmE"
                     /locus_tag="KR294_000134"
     CDS             complement(134196..135575)
                     /gene="mnmE"
                     /locus_tag="KR294_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HBH0238252.1"
                     /translation="MFIDDTIAAIATAPGEGGIGILRISGEKALKVAEEIFKSMSGKS
                     IEEYNKRTLIYGNIVDNENVIDEVLLAYMKGPNSYTGEDVIEINCHGGFISVKKILEL
                     ILSKDVRLAEAGEFTKRAFLNGRIDLSQAEAVIDVIKAKTDIAHEVAQNQLEGSLSKK
                     IRELRDKVTEILAHVEVAIDYPEEDIEHITYQTLKEKTDELKKDIKKLYDTAESGKIL
                     REGLKTVIVGKPNVGKSSLLNSILGENRAIVTDIPGTTRDVIEEFVNIKGIPLKIVDT
                     AGIRDTDDIVEKIGVEKSKESFTSADLIVMVLDASRKLSEEDIEILEKLKDKQTIVLL
                     NKNDLKQEIEEEKILKYVENNSIIKISALQQEGIEELQDKIESMVYKGSIKNNSSLVV
                     TNSRHKDALSKAYKSATDALIALEQSMPFDFVEVDLKNIWDYLGYINGDTVTEDLLDN
                     IFHNFCIGK"
     gene            complement(135687..136316)
                     /locus_tag="KR294_000135"
     CDS             complement(135687..136316)
                     /locus_tag="KR294_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HBH0238253.1"
                     /translation="MRKSLKLIKSKSKEEAISKAIAELNLKAEDIEVEILENPSKGFL
                     GFIGAKDGTYEIFVIEREVDVAKNFIEVMLKNANVDAKVNVSQKDNLIMVDIEGKEAA
                     SLIGRRGETLDSIQFLTGLALNKINKDSHTRVLVDIENYRSKREESLIRYANKVAREV
                     AKTRKTKKLDYMNPYERRIIHSALQNDKYVITYSEGTDPYRRLVIECKR"
     gene            complement(136285..136992)
                     /locus_tag="KR294_000136"
     CDS             complement(136285..136992)
                     /locus_tag="KR294_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HBH0238254.1"
                     /translation="MNIIGNFLGLILKVIFEFVNHYGISIILFTILVKIILLPLTIKQ
                     TKSTKAMQDIQPRIKEIQEKYKNKPEKQNEEIVKLYGEAKINPLSGCLPLLIQFPILI
                     GLFSVLREPVAHGVFANKAAFLAADNGFLWIKSLTSPDYVLAVFSGASAYVMQKVMTP
                     KDQLQGSMKVMTYVMAGMSFYWGFIFPAGLTLYWTVSNLFSIAQYYLIMNPLKAKLAA
                     NSKEEKVNEKKPKINKK"
     gene            complement(137024..137275)
                     /gene="yidD"
                     /locus_tag="KR294_000137"
     CDS             complement(137024..137275)
                     /gene="yidD"
                     /locus_tag="KR294_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HBH0238255.1"
                     /translation="MNKIIYILKEISKHLSNLCIYLVRFYQKYISPLKGPTCRFYPTC
                     SQYSIEAFKKYGFVKGMYLTIRRLLKCHPFHPGGYDPLK"
     gene            complement(137307..137651)
                     /gene="rnpA"
                     /locus_tag="KR294_000138"
     CDS             complement(137307..137651)
                     /gene="rnpA"
                     /locus_tag="KR294_000138"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HBH0238256.1"
                     /translation="MDFNRTKGLKKDSDFRKVYKHGKSFANKYLVIYILKNKSDYSRV
                     GISVSKKVGKAITRNRVRRLIKEAYRLNIDEKIKPGYDIVFIARVSSKDATFKDIDKS
                     IKNLVKRTDISI"
     gene            complement(137729..137866)
                     /gene="rpmH"
                     /locus_tag="KR294_000139"
     CDS             complement(137729..137866)
                     /gene="rpmH"
                     /locus_tag="KR294_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HBH0238257.1"
                     /translation="MSKRTYQPKKRQRSKEHGFRKRMKTSNGRNVLKRRRAKGRNRLT
                     H"
     gene            138522..139844
                     /gene="dnaA"
                     /locus_tag="KR294_000140"
     CDS             138522..139844
                     /gene="dnaA"
                     /locus_tag="KR294_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HBH0238258.1"
                     /translation="MMDIVSLWDKTLQLIKGDLTSVSFNTFFKNIVPLKIHLNDLILL
                     APSDFNKDILENRYLHLIEDAISQLSLKKYNIKFVLSEKEVADLNSDSTDLNYRVLYP
                     NLNPKYTFDTFVIGNSNRFAHAACVAVAESPAKAYNPLFLYGGVGLGKTHLMHAIGHH
                     IVSQKKDSKVVYVSSEKFTNELINSIKDDKNEEFRNKYRNVDVLLIDDIQFIAGKERT
                     QEEFFHTFNTLHEANKQIIISSDRPPKDIPTLEDRLRSRFEMGLITDIQAPDFETRIA
                     ILRKKAQLERIDVPNEVMSYIAKNIKSNIRELEGALTRVVAYSSLSNRVISFDLATEA
                     LKDIITTSKNEEINVLRIKEKVSSVFNLKMEDFNSKKRTRSIAYPRQIAMYLTRELTD
                     LSLPKIGEEFGGRDHTTVIHAHDKVSKDIEESEEIKTKIDKIISDLKG"
     gene            140086..141192
                     /locus_tag="KR294_000141"
     CDS             140086..141192
                     /locus_tag="KR294_000141"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HBH0238259.1"
                     /translation="MKIICNQKILANRIGIAQKAINGKTTIELLKGILISTEEGQLKL
                     TGYDAEIGIETYVQAEIIEKGDVVVDARLFGDIIRKLPDSFVEIETDSENNIYINCVN
                     SRFKIKGYAAKEFPKLPELNEEDLYSIPQEILKNMIKQTVFAISQDQTKPVLMGELLE
                     IVDRNLNLVAIDGYRLAVKSCSVDSLTENIKVIIPGKTLIDVNSLLSGEDNVKVGFNE
                     KNAIFIINDTKIITRLLEGDFIDYKKLLPREHNSRVKLNTKELLNSIERASLLSQSEK
                     NNLIKLSIRDKVMAITSNTEKGNVYEEVEIDLDGDYLDIAFNSRYFIEGLKNIDNEEI
                     FIEFTTNVNPCIIKPTDDVNYIYLLLPVRISSNI"
     gene            141329..141535
                     /gene="yaaA"
                     /locus_tag="KR294_000142"
     CDS             141329..141535
                     /gene="yaaA"
                     /locus_tag="KR294_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HBH0238260.1"
                     /translation="MTEITIESEYIKLDQFLKLAEIASTGGHAKFLIQEGLVTVNDEI
                     ELRRGKKIKSGDIVEIEGTKIKVL"
     gene            141552..142667
                     /gene="recF"
                     /locus_tag="KR294_000143"
     CDS             141552..142667
                     /gene="recF"
                     /locus_tag="KR294_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HBH0238261.1"
                     /translation="MKLKSLQLVNFRNYKKLHLEFNGKVNLLVGKNGQGKTNIVESIY
                     MLSFGKSFRTNKDKEMVRFNSENLYIGGSFSKYNKYSLIELIIGKDKKGIRINKVPLQ
                     KIQELLGNLNVVIFSPEDLRLVKEGPKERRAFIDKEISQIIPKYYKYLTNYNKTLSQR
                     SRVLKNIHVDEALLDVYDDTLAKYGSYIYILRRDFIKKIANISENMHMNLTNGVERLS
                     IRYKNQINITDEDTIDTVYNKFLAKLSSNRPNDIESKTTRYGIHKDDLNIFINDLDAR
                     LFGSQGQQRTASISLKLSEIELIKNEVEEYPVLILDDVFSELDEARQKLLVNNLSNVQ
                     MFITSAEVSHKKIFDEKNVTIFNIENGDVISIENGGN"
     gene            142668..144569
                     /gene="gyrB"
                     /locus_tag="KR294_000144"
     CDS             142668..144569
                     /gene="gyrB"
                     /locus_tag="KR294_000144"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003226808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HBH0238262.1"
                     /translation="MKQEYGASQIQVLEGLEAVRKRPGMYIGSTSPRGLHHLVYEVVD
                     NSIDEALQGYCSDIYVSINEDGSVLVKDNGRGIPVEIHPKTGKSTLETVLTNLHAGGK
                     FGGGGYKVSGGLHGVGVSVVNALSKWMVAEVYLNGKRYKQTYEKGLPTSKLEVVGESQ
                     DKGTMIQFMPDETIFDEIEFKYETLEYRLRELSFLNKGIKIVFEDKREGQEKRKEFHY
                     TGGLVEYIKYLNKSRTGIHDDIVYIDKKVDDCFVELAMQYTDGYTENIYSFANNINTH
                     EGGSHLSGFKAALTKTVNDYAKRNKFLKENDVNLLGEDIREGLTAVVSVKLPEPQFEG
                     QTKTKLGNSFMRGIVDSVTVDELGSFLEENPSTARIIVDKALRAQRAREAAKKARELT
                     RRKSVLESTSLPGKLADCAEKDPSKSEIFLVEGDSAGGSAKQGRDRNSQAILPLRGKI
                     LNVEKSRLDRILSSDEIKNMITAYGCGIGEDFDIDKARYHKIIIMTDADVDGAHIRTL
                     LLTFFFRYMRPLIDEGYVYAAQPPLYKVTKQKKEHYVYSDKELNILLDEIGRNGVELQ
                     RYKGLGEMNAEQLWETTMNPETRTLLQVTVEDAAIADEVFSMLMGDKVAPRKEFIEEN
                     ARFVRNLDI"
     gene            144589..147015
                     /gene="gyrA"
                     /locus_tag="KR294_000145"
     CDS             144589..147015
                     /gene="gyrA"
                     /locus_tag="KR294_000145"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HBH0238263.1"
                     /translation="MEENNKILPIEIAEEMKKSYIDYSMSVIAGRALPDVRDGLKPVH
                     RRILYSMSELNLTPDKPYRKSARIVGDVLGKYHPHGDTAVYYAMVRMAQDFSTRALLV
                     DGHGNFGSVDGDSPAAMRYTEAKMSKLSLELLRDIEKETVDFKPNFDESLKEPSVLPA
                     RYPNLLVNGSNGIAVGMATSIPPHNLAEVIDATVYLIDNPECSVDDLIKFVQGPDFPT
                     AAIIMGKESIAEAYRTGRGKVKVRSRAFIEELPKGKQQIIVTEIPYQVNKAKLVERIA
                     ELVKEKRIEGISDLRDESNRNGMRIVIELKRDANANIVLNNLYKHSQMEDTFSIIMLA
                     LVDGQPRVLNLKQILYHYIKHQEDVVTRRTKFELNKAEARAHILEGLKIALDNIDAVI
                     SLIRASKTGQEAKLGLIEKFKLTEIQAQAILDMRLQRLTGLERDKIEAEYEDLIKKIN
                     RLKEILADERLLLNVIKDEITIIKENYSDERRTEIRHAEGEIDMRDLISDEEIAITLT
                     HFGYIKRLPSDTYKSQKRGGRGISALTTREEDFVRHLVTTTTHSRLLFFTNKGRVFKL
                     NAYEIPEGKRQAKGTAIVNLLQLSADEKIATLIPIDGNDENEYLLLATKKGIVKKTKR
                     EEFKNINKSGLIAIGLRDDDELIGVELTDGKQEVLLVTKEGMSIRFDENDIRYMGRTA
                     MGVKGITLSKEDFVVSMNLCSKGTDVLVVSKNGFGKRTNIEEYRSQIRAGKGIKTYNI
                     SEKTGTIVGADMVNEDDEIMIINSDGVLIRIRVNEISLFGRVTSGVKLMKTNDEVNVV
                     SIAKINIEEE"
     gene            147084..147380
                     /locus_tag="KR294_000146"
     CDS             147084..147380
                     /locus_tag="KR294_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBH0238264.1"
                     /translation="MCNKRSCKKGGFLLLGAILGFIFGMFFAPKKGSELRKETKEKFN
                     DVKENPKEVLHETFNDVKERIINLVDDDNNEEDIKISEEDIVISKSFDDEGDVN"
     gene            147380..147640
                     /locus_tag="KR294_000147"
     CDS             147380..147640
                     /locus_tag="KR294_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HBH0238265.1"
                     /translation="MNAWGWQIGAVLVGSSALIVAIYLAKTLNSINKVVEKAYKIVDY
                     NERHIQDIVENASSISKGIDDIVYVINKILSIGNIFKIIKRK"
     gene            147652..147969
                     /locus_tag="KR294_000148"
     CDS             147652..147969
                     /locus_tag="KR294_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="STAS domain-containing protein"
                     /protein_id="HBH0238266.1"
                     /translation="MSMNIDSNLDSQNKFWNVCLDGELDVSTADKLKEHLHALIEKNM
                     LDVKINLKDLDYIDSTGLGAMIGVLKKLKINEKEIYIVNPKSNVRKIFTITGLDKIFK
                     VEG"
     gene            147994..148380
                     /locus_tag="KR294_000149"
     CDS             147994..148380
                     /locus_tag="KR294_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH0238267.1"
                     /translation="MEITTNPDYVSIIRLTASGIANKMGFPIDDIEDIKVAVSEACTN
                     AIKHSKDDVFNIVFNILDNAINIEIQDNGKGYDVSSISTPDLENPKESGLGLFIIKTL
                     MDDVDIESEHNQGTKIKMTKYLGVDI"
     gene            148380..149153
                     /locus_tag="KR294_000150"
     CDS             148380..149153
                     /locus_tag="KR294_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SigB/SigF/SigG family RNA polymerase sigma
                     factor"
                     /protein_id="HBH0238268.1"
                     /translation="MKNVANATHYLNMDTKELFNLYNKNKNVDIRNILIERHLYLARL
                     LAKKYINKGVDFEDIYQVASLALIYAIDRYDVEKGFEFSSFATPTIVGEIKKYFRDKV
                     WTLRVPRRIQELSKKISDAKIKLEQENKKHPKVKDIADYIGVSEEDVLEAMEASYGYQ
                     PMSLDSSSNDDSEDKDITLIDKIGKEEGNFGSIEYEDFINKFIETLNELEVKIFKDRF
                     FFDKTQSSIAKELGISQMTVSRLEKKVVEKLKKEYEKNL"
BASE COUNT        48442 a        26065 c        16924 g        57842 t
ORIGIN      
        1 aagagatgcc tctcaaatat attatcccgt attagcatac ctttcggtat gttatccgtg
       61 tgtacagggt aggttaccca cgcgttactc acccgtccgc cgctctttac cgaagtaaat
      121 cgctcaactt gcatgtgtta ggcacgccgc cagcgttcat cctgagccag gatcaaactc
      181 tcaaataaaa gtttatcagg ctcagatact attgttatca aaatatctgg ctttatggtt
      241 tgtttcttgt tttataaatt aacctactgt ttaattttca aagttcattt tttatgtttg
      301 cccttttctt aaggacaagt aatactatat catcttaaaa atgtttcgtc aatacttttt
      361 ttgtttttta ttttaaaaaa ggttataact tttgtttttt ttaataaata taattaaaac
      421 taatagatat aacccttgat attacaaaca atacatgcat atataatttt acctattttg
      481 caattttatt ttcataagaa tatgaattag ctctcactct atctgcccaa acatttatac
      541 tcttaacttt attaacatta gttgtaccct caaaaatatc cattgcatcc ttacaaaaat
      601 atatcataac atcaagaacc aaaaatccaa cacaaaataa acataaaaaa ttaattactt
      661 gaaacatcag acattccccc aataattttt tatatatagt attctcataa attattcttt
      721 ttaccttctc ataaattatt ctaaatattt tcataataaa ttactttcaa tcatattttc
      781 taaatataaa gtctcaatca acaaaaacta atatcaattt ctaacgtttg ttggtaattt
      841 ataaattaaa tatctaaaag aatctttgaa gcatataaaa agcattctac actgacattt
      901 taaataaaat ttagctattt attgataatt taatagctaa actttattta aaacttagta
      961 gaatgctaat atttcttagt tttcttcttc tttatttgga ttgttatcaa taggtttcat
     1021 agtcgggaat aataatacat ctcttataga tggagagtta gttaataaca taattactct
     1081 atctatacct attcctagtc ctcctgtagg aggtagacct acctctaatg cttttaagaa
     1141 atcttcatcc atttcaaaag cttcatcatc acctaattct ctttttctta attggtctat
     1201 aaatcttcct ttttggtcaa tagggtcatt aagttcagaa aatgcattag ctaactccca
     1261 cttattagca aatgcctcaa atctatcagt tcttcttggg tcttcaacat ttctcttaga
     1321 taatggagat acttcaactg gatgatgagt tataaatgtt ggttggatta atttatcttc
     1381 tccaaattct tcaaagaaag catttattac ttctcctctt ctcattccag gttttatctc
     1441 tatacctttt tctctagcaa cttctagtgc ctcttcatct gtatttatag tagaaaaatc
     1501 tacaccagaa tattctttaa cacaatcttc catactcatt cttttccaag gtggtgtaaa
     1561 gtttatttct gttccttgat agttaactat catacttcct gtagcaactt cagccatatg
     1621 tgcaataaca ttttctgtta tttccatcat atcagtatag tctgcatatg cttgatataa
     1681 ttctattgca gtatattcag gattatgttt taaatccata ccttcatttc taaacattct
     1741 tcccatttca taaactttat caaatccacc aacaataagt ctttttaaat acaattcatt
     1801 cgctattctt aaatacattg gtatatgtaa agtattatga ttagttataa atggtctagc
     1861 atttgcccca cctgctatag tatttaatat tggagtctca acttctaaaa atcctctatc
     1921 atctaagtat gctcttaatg cttttaatgc ttttgttcta attaaaaaag cattttttac
     1981 ttctggattt actattaagt caacatatct ttgtctatat cttagttctt ggtcttttaa
     2041 tccatgatat ttttctggta aaacttgtaa agatttacat agtaatacta cagatttagc
     2101 ctttacagat atttcacctt ttttagtttt aaagatttct ccttcaattc caactatatc
     2161 tccaatatca tatgttgaaa atacactata ttcttcctct cctatagcat ctagtcttac
     2221 ataagattgg attcttccct cttggtcttg aatatctata aagccagctt tcccttgtat
     2281 tctcttgctc attatacgtc ctgctatttt tgtagtttta ccctcaagag aatcaaagtt
     2341 atcttttata tccatagaat aatgagttct atcatatcta ctttctttaa aaggatctct
     2401 acctgattct tgtaattttt ttagtttatc tcttcttact tgaagtactt cactaaggtc
     2461 ttcttgaatt tgcgcttctt cattgctttg ttgattattt ttcatttttt tcctccaaat
     2521 tatcttctta tttctaatat ttcaaactta gcaactccat caggaacttg cacttccaca
     2581 acttctttcg cagctctacc taaaagtgct ttccctacag gagattcgtt tgatatttta
     2641 ccatcatatg ggtctgcttc tgtcgaacca actatagtat attcaacctc ttcatcaaat
     2701 tctaaatcct taactttaac tattgatcct attgtaacaa cattaaggtc tattttgctt
     2761 tcatctatga taacagcttt tctaaccata ttttctaatt ttaaaattct ttcttcaact
     2821 tgtgcttgtt cctttttagc ttcatcatac tcagcatttt cagataaatc accaaaagat
     2881 atagcaactt ttattctctc tgcaacttct tttctcttta caacctttaa gttttctaat
     2941 tcttcttcta atttatcata tccctcttgt gtcaataaaa actctttatt ttcttccatt
     3001 ataaatacaa ctccttcaca aatttcttag gaattttcct aattatattt taaaaatttt
     3061 ataatctttt tttaatttat gcgctatatt ataagtcact attattttta tgtcaaggag
     3121 tcttccatat agtactccaa tttcgacaca acttcttgat agtcttctat tttgttaatt
     3181 tcatccctta attttgcaga gtttctaagt ccttttaaat accaagcgat gtgttttctc
     3241 atttccctta cagctacata ctctccatgt tcttctactg caagttttaa atgcttaatg
     3301 gcagtactta ttttttcgtt aagagttggc tctggcaaaa tctcgcctgt attcatataa
     3361 tggtttattc ttttaaatat ccaagggtta ccttgagcac ccctacctat cattatagca
     3421 tcacaaccag ttttgtctaa catatttatt gaatcttcta ttgtaaatac atcaccattt
     3481 cctataacag gtatactcaa atttttctta atctctgcaa ttatatccca gtctgctttg
     3541 cctgtataaa actgttctct agttcttcca tgtattgcta aagcacttat tccacaatcc
     3601 tctgctatct ttgctatttc aacagcattt acactattat catcccagcc ttttcgaatc
     3661 tttaaagtca ctggcttttt tgagttcttc actactgccc tcaatacctc ttctgcaagc
     3721 ttaggatttt tcataagtgc tgaaccatct ccatttttaa ctacttttgg agctggacac
     3781 cccatattta tatcgagaat ctcatttgaa taatcattca ttatctctgc tgctcttccc
     3841 ataaactctg gttctgaacc gaatatctga actgctacag gatgttcttc ctcttctatc
     3901 ttaagcattt ttttagtatt ttcatcatca tagcaaagtg ccttaccatt tatcatttct
     3961 gtatataaaa gcccacatcc ttgttcttta caaattaatc taaatggaag gtctgttaca
     4021 cctgccatag gtgatagaaa aactttattt ttcaattcta aatttcctat tttcattgtt
     4081 tttctcctat ttttgccttt attttgtgat ttaactttaa attcttattt cctcattata
     4141 atataccaca tatagctaga aatctatcat aaaaagggaa ttggatatat aacccaattc
     4201 cctgtatatt aattattctt ggtttttttc atatattatt ctcaatcctt ctagtgttaa
     4261 aaaaccatct acataatcta tacttttcgt ctctgaagca atcagtttag ctaacccacc
     4321 tgtagctata accttaacat catcacaatt caattctttc ttcatcatac ttattatttt
     4381 gtcaactaaa ccaacatatc cataaattat tccagattgc atggctgata cagtactctt
     4441 acaaatagtc atacctggct tagctaattc tactctaggt aatttagacg cactttgaaa
     4501 taacgcctca ctagatattt ttattcctgg tgctattgtt ccacccaaat attcaccttt
     4561 ttcagagata gcacaaaatg tagttgctgt tccaaaatca acaagtatac ttggtgctcc
     4621 atacttttct atccctgcta cagcattaac tattctatct gccccaactt gttttggatt
     4681 atcatatttt atatttagac ctgtttttat gcctggacct actattaatg gctgtttttt
     4741 acagtacttt atacaaaagt tttcaagaga atgcataaca ttcggaacta cagatgatat
     4801 tataacatca tcaatatcac ttatattcac attatcataa tcaaataggt tacttattag
     4861 gattccatat tcatcagacg ttttttctct atctgtttta attctccagt aattaactaa
     4921 tttgtcacct ttatatatac ctaaaaccat attagtattt ccaacatcaa atactagaag
     4981 catatgtcat taaccttctt tctatttttt gcttttctta agtacagtgg caacagcagc
     5041 tactactaaa gcccctacta ttgcttctgg caccccattt gctgcggcaa gagccattat
     5101 tacttttcct gctgaaccac ttttacccat tgcatgaaga tacttgtcag catataagac
     5161 atatatcatt cctaaaactc cagctgtatt taacagagaa cctattgccc ctgtaattaa
     5221 acctgatatg tataccttat ttgtagcctt aattattaac tgatatacat aataagctaa
     5281 tacacctatc ataactcttg gtaatattga aactaatgga tttataaaaa caaaagatgt
     5341 tactgttggg tttgttatag catttaagag acttgatatc ccaaatataa atcctattgc
     5401 tgccccaact attggtcctt ccataatagc tccaataata actggtatgt gcattatagt
     5461 tgcttttgta ggtccaactg gaataaatcc caatggagtc atagatagca taatagaaat
     5521 agctgatagt actcctatta tagtcatctt tcttacattt acttttctta ctgatgcact
     5581 tgtgttcatc ataaaaaata cacctccgtt ccagctcatt aagatgccgg actacttaat
     5641 tttttaattt ttttcgtttt tttcttataa ctatgagtca agctaccatt gtaggatgcc
     5701 cgctctaaca agaataattt tatcaagatg agttgccatt gtcaacaatt tgacaagaaa
     5761 aatatgctaa tttcatcata tttctcgttt ttttactata tctttatatg ccattatatt
     5821 ttctacacta tccgcttttt ttactgcatt tattatactt ttttccacaa cctctacagc
     5881 caatgaacct actaatgtta tatctgcttc tatttctcct gttgatattg tgaatattgt
     5941 atctccatca tgaggtgtat ggataggaaa aatagactta gcatatccat catgtcccat
     6001 ttgagatatc tttttacatc cagctttggt taacttagca tttgttgcaa ttatcccaat
     6061 tgtagtatta tctacactaa atccaccttt actttcacct tgtttcatta atttatatgt
     6121 atcaattgtt tctgtctttt tatcatttaa agcaccagct ataaccttac cattttcata
     6181 aacatctcca agagcattta cagcaattaa tgcagataca attagaccat tatctaattt
     6241 tatagaatag ctacctattc cgcctttcat agcatattcc tgacctctta tctttccaac
     6301 agtggctcca caacctgctc cataatttcc ttgatttaaa atatcagtat ttgcaacttc
     6361 acaagctcta taacccatct ttaaatctgg tctacattta aagctcccta ctcctaaatc
     6421 aaataaaact gctcctacaa ctataggcac tttacctaca cctacatcaa atccaattcc
     6481 tttttcttct aagtatctac ttacaccaca agtggattca agaccatatg cagaacctcc
     6541 agccaaaact actgcatgaa ctttttgaac catatttaca gggtctaata aatcggtttc
     6601 tctagtacct ggagcagagc cccttacatc aacaccgcaa gtagctcctt cttcacatat
     6661 tactactgtg cacccagtaa gaccatttct atcctcaacc tgcccaacct ttaagccttc
     6721 tatatccaaa atattattat acatatcctt tttctcctct tatagaaact tcacctgaaa
     6781 taatttcttt tatacttcca tcacttcttt gaactaataa atttccctct tcatttatgt
     6841 ctaaacattt cactagttct ctattatctc cttttaatac atatatattt ttatctataa
     6901 ttgcagaata atctctacat atttttaagg ttttttcttt ggaattattt acagtataat
     6961 ctaaatataa tttttcaaat tcagtcaata cattcctaac aatatctact ctggataaca
     7021 tatacccttc tttatacaat gatgtggctt tgtcagctat ttcttgttca aaatccatta
     7081 ttttaacatt tattccaatt ccaagaacaa cataatttgt tctttcaatt tcagcagata
     7141 actctgttaa tataccacat attttttttc catttaaaat aacatcattt ggccatttta
     7201 ttaatgtatt tgctcctaga ttgtttaaag ctttcgttac acttgctcct gctattaaag
     7261 ttataaatgg ggctttgaat ggttccatat ctggttttaa tataatactc atccagattc
     7321 cttcatgagg ttttgaatcc catcttcttc ccaatcgtcc tttccccata tcttgatgtt
     7381 cacttaaaat cacagtccca tctacactat ttatagctat ccttttagca tgttcatttg
     7441 ttgaatctat agtgtcaaga tgttcaatat tttttccaat aaactctgta tctaatttat
     7501 agtaaatatt ctgtgggctt aataaatcag ttggattttc cgctaatcga tacccttttt
     7561 tatttacaga ttctatatta tatccctctt cttttaaggc tttcatatgt ttccatatag
     7621 ctgcacgtga cacccctaat tgttttgata attcttctcc tgaaataaat tcagatttat
     7681 tatttaatat aatctctatt attttatctc tcatatttca cctctaatat gacataattt
     7741 catgacttat tttcttctaa taaataatta tacattatta atatactttt aatactatta
     7801 attttaaatt tcctttttaa ttattataat ggttgtttta tattttatat tgatgattta
     7861 tataatttta cattttattt aaataatttt aaaataataa aaaaactgaa agtatcaatt
     7921 aaattaatac atgcaaatat aatttgctta ttaatttaat attatacttt cagttttagt
     7981 atttaatcca catcagataa taatcttaaa atgaccaagg tcttaaaact atttatcttt
     8041 atcagattta tcttctaaat ttttatttat atcaataaca ttgtttcttt cttcttcatc
     8101 tttttctaat tttatagtta attgttcttc aacttcttta gaagaatttt cctctgtaac
     8161 tgcattttca atttcattca gaggtaactc tttattaaat gcttttacaa attgttctgc
     8221 atctaaagtt tcatatataa gtaaagcttg tgctacatac tctaatctat ccatattttc
     8281 ttgtaatata cttcttgtct tatcatatgc accatcaact atacgctttg tttcttggtc
     8341 tatctcaaaa gcaacttctt cagaataatt tctcttactt gaaaaactat tacctaggaa
     8401 tacttcatca tcactgtcaa atgacattgg accaagttta gaactcattc catactttgt
     8461 taccatactt cttgcagtag ctgtaactct ttctaagtca tttgaagcac ctgtagatac
     8521 atccttaagt actagctctt ctgctactct accaccaagt aaaactacaa tattttcttt
     8581 catttcattt tttgtagcat agaacttatc ttcaacagga agttgcattg taaaccctcc
     8641 agctcttcct cttggaacta ttgtaacttg atgaacagga cttacttctt caagtacatg
     8701 ggcacaaact gcatgccctc cttcatggta tgctgtaagt cttctttctt tctcacttat
     8761 tactttcgat tttttagcca cacctgctat aacctttgtt atagcttctt ctatagtttc
     8821 catcttaatt ttcttttctc tttttctagc tgttaatatt gcagcctcat tcattaagtt
     8881 ctctatatca gcaggagtaa atcctggtgt tcttctagcc aagacatcca tttttacatc
     8941 atcacttaat ggtttatttc ttgagtgaac tttaaatata gcctctctac cttttacatc
     9001 tggtgtacca acaacaactt gtctgtcaaa tcttcctggt ctaagtaaag ctgggtcaag
     9061 tatatctggt ctatttgtag ctgccatgat tattatacct tgatttaccc caaatccatc
     9121 catttcaact agaagttgat taagagtttg ctctctttca tcatgacctc caccaagacc
     9181 tgcacctctt tttctaccaa ctgcatcaat ttcatctatg aatatgatag ctggagcact
     9241 tttcttagcc tgttcaaata aatctcttac tcttgaagca ccaaccccaa caaacatctc
     9301 aacgaaatca gaaccactta tactgaaaaa gggaactcct gcttctcctg caactgctct
     9361 tgatagatat gttttaccag ttccaggagg tcctaccata agcattcctt ttggtattct
     9421 tgcacccaat tcaatatatt tcttaggatt ctttaagaaa tctactacct cctgcaaatc
     9481 ttctttttcc tcatctagtc cagctacatc tttaaatgta actctagttt tttcatcatc
     9541 tttatgaacc ttagcttttg atttgccaaa actcataacc tttccgcctc caccttgaga
     9601 ctgattcata aacacgaacc aaataatcac catgaagaat attaacagta atgtaggcaa
     9661 catttcgaca aaccaaggtg tagatggctt agcttcacca ccaaaagtta gtttcccagc
     9721 cttagcttgg tctaacacct catctgcaag tttatttccc atcacttctg ttggaacata
     9781 tgacttaaac tttgtatttg tatcttttat agtaccttct acagaagttt gatttacaaa
     9841 gtataatctt gatatattct catctgttaa ttctctatat acttcagaga attttaaatc
     9901 ttttattttt tctgtaggct tacctgagaa ttgaactata cctactataa ttataaaaac
     9961 aagtagataa aaacctgccc cttttagcaa cttattcaat atagaagccc tcctttcata
    10021 cattgctttg ccctataatt tgttaaaatt aatttttaat acttcttttg tgttttcatc
    10081 aattttataa ttttcactga ttttataatc tccaacacat attattcctt cactatctgt
    10141 gattatagga attttacatc tttcttctct tgggattttt aaatctatga ataaatcttt
    10201 cactttttta cttcccatag caagctttat cttatcacct tgccttctgc ttcttattac
    10261 tataccccct tttaccttat taaaatcaaa ccctttagat gaattgtcta atttcatact
    10321 cttataccta tctatgctca ttacttgggt ctcaataatt tgttttaatt cttttatttt
    10381 aataaaccca ttactaggta cattgtaata aaattcaatt tcctcattaa caatttcctc
    10441 attcgttaat attatactgt ctttttttct ataaacaaat atatttcttg gaagagttaa
    10501 cattttattt acttttgaat tatcttctaa agacattata tcttctatat gtctttggtc
    10561 aacaaaatta gtatctccta gtatatgttt tatggaattt ctaagaactc taactttgat
    10621 agcatcatgt aagcaaacaa aatcgtctaa atttatctct acaaagcctt tttcttttat
    10681 atttgaaact tctctaaatt tagcttctgc ctctttctca atataatcgt tatcactttt
    10741 taaactattg ctcatcctca ctatagattc tattacattt gaattaaaat tatccttcat
    10801 atatggtaaa aggtctaacc ttatcttatt tctagtgtat atattttcta aatttgtttt
    10861 atctatcctc ggatttaaat tataagcttc acaatactcc tctatctcat ttctttccac
    10921 gtctaatatg ggtctaatta tgcaattatc tctaatataa tcaattccct ttaagccttt
    10981 taaacctgtt cctctcatga tacgcatcat aaccgtttcg gcttggtcat tgagattatg
    11041 acctattgct attttattgg ctttaatctt atccttaatt tcataaaaca tttcatatct
    11101 tagcttcctt gctccttctt ctaatgataa tccctcattt tcacaatatt ttggtacatt
    11161 aatagacttt acaaagaata taattcccat atcctcacaa agtttagata catataatgc
    11221 atctttttga gcttctatcc ctcttatttg atggtttaaa tgtgctgcat atatttctat
    11281 attaaaatct ttttttaatc tatttagtac atgcaataaa caaactgaat caggtcctcc
    11341 agaaagacct aaaactattt tatcgccttt ttgtattaaa ttatgtttat ttatagtact
    11401 tagtacctta tcaaatatca tatttatccc tcttacactt agttttattc acttttaagt
    11461 atactttcta taaaaaaacg ctaaaccctt gtatcaattt taagaaatta aagtttaata
    11521 taaatataat aataccaaat aaattaaata aaaggtagtt ttttcactac ctttataaaa
    11581 tttctggaaa atagccatag ttattattta gtacctatgt atatatctat tttattccta
    11641 cctaaaaata aatcttgtac ctttatatta tagtctattt tcaattttat gtgttcccct
    11701 tcttgtatat ttatatctaa ttctcttgta tcaatatcaa ttaataaagt accttgtggg
    11761 gtcacatact ttgtagtact actttctcca catttaaaca gcattgttga gttaatagca
    11821 ccaaactttt tgatactaac ttgattttta agtatcttta tagtattagt tatttctata
    11881 tcttcttctt tttccttgta aataacatat attccatcat ttttataaaa aattttacca
    11941 aaggcagtca tctctatggt gtccatattt cctttttcat catattgtct agtatttata
    12001 cttattttta cactcaacga tttttcctcc atagattctt catataaact agtatttttg
    12061 tatttctact ttttgaatct tatcaatttt tttctttaag aactctcttg ctatatctga
    12121 aaatttttca ggtatatctg atacataata ttgataagtt ccatgaattt ctgtattgtt
    12181 tataatattt tgcacctcta aaatcttttt taaatccttt gcagtctctt tagctggatt
    12241 aacaagtttt atatgctctc caacttcttc acctattgtt ctctttaaaa taggataatg
    12301 agtacatcct aacactaaag aatctatatt tttttctttc aattcttgta aatatatctt
    12361 tgctgtcagt ttagccactt ctgtatttgc ccatccttct tcaacaatag gcacaaataa
    12421 aggacatgct ttattaacaa tttctatact ctcatctatt ttagatattt ccaagttgta
    12481 tgcttttgaa cttatagttc cttcagttcc tattattcct acaattttgt tttttgtaga
    12541 acttacagct gttctagctc ctgcttctat aactccaatt atcggtatat catatttttc
    12601 ttgagcttct tttaagcttc ttgcagtagc agtgttacat gctataacta tagcttttac
    12661 accttttgtt tttaaaaagt ttatagcttg aaaagtatat ttaattatag tttctttgga
    12721 tcttgaacca tatggtattc tggcagtatc tccaaagtat attatatcct catttggtaa
    12781 tatcttcatt atctctttta gaactgttaa tccacctaat cccgaatcaa aaactcctat
    12841 tggtttattg ttcatcttta tacaacacct actttacatt tttgtgttta acaacaactt
    12901 atttatcgct aaaatttata tttatattca taattaatat attattacct aaatgattat
    12961 tatagtttat tttacacaaa aaataaagga gctatcttaa attagaaaat aatttctaca
    13021 aaaagacaac tcctttcact acttaaaaat ttaaatttat tttgcaaaca catgatttcc
    13081 tattctcata taaggattca atctatttat ccatttgcaa gtggctattt ctggattcca
    13141 aaaatatact gctttattag ttgggtcagt tccataaaga gcttcctgag ctgctttacg
    13201 tgctgagtct gttggtgcca tctttattga accatcaagc acaactgaga aagcattttt
    13261 ttgatatatg acttcttcta ttgtgtctgg aaatctaggg tccaatactc tatttattac
    13321 tacagctgct acagcaacct gtccctcata gctttctcct ctagcttctc ctgcaaccaa
    13381 cttagataat aacatcaagt cattatcaga taaatttatt acttctttct ttgctatatt
    13441 tttttcttgt ttgtttactt tcttaatatt ttctgttggt tcatatgcaa atacctcttt
    13501 aataggcata aatataaaag tcaaagctaa tagtgtagcc atcagtttac tccacctgtc
    13561 catgattaaa accactcctt acattcttat ttttaaaatt ttttctctaa atccttgact
    13621 acttcaagta ctttaaattt aatttttact ctacttgttt tttttggtgt atcttgtttt
    13681 attaacttat attctttatc agttaaaact tccttcaact tatcatctgt agatttatct
    13741 atcactccat tagattcatc aacaaaacat agtggaggga acataacaca ccaccagttt
    13801 tttccttcac ctttcccaat gataatcttt aatgctttat attcaccagc tggaagaact
    13861 atattagaat attgtttagt agggaaattg ctatattgta tacctacctt tacactgtaa
    13921 ttatatccat ttttaagaat aatattttta cttatttctt ccaaactact atattccttt
    13981 tttataatag cttcactttc ttttatactt tttgaatttt gaagctttgg ctgtaaatat
    14041 tttattactt catctctaac ttttagttta agttcttggt cttcatctgt attgctgttt
    14101 gctataacat gaaatcttat taatttatct ttataatctt ttgatatatt gtctactttt
    14161 tttacctcac catttattac tattgtcatt attgatatga ctgatataag acttaatatt
    14221 aatagtccca atctaatctt aatttttctc attgaaaatt ccccctcaag ataaatttat
    14281 atcatcaatt atgtccaatt aaatttaatt tattcataat attttttaat actaataaaa
    14341 aaagctatct taaaatgatt acaatcattt taaaatagct ttttaaacct tatattttat
    14401 aagtctttac taatcatagc cttatctatc ataaactgct ctgctttttc tatatgctct
    14461 gtagcatact tcttggatag ctcactatca cctttaatta tagcatcaag taaatattta
    14521 tgctcttcaa caatattatg tgatgtatca taagcagaca tataggtaac tctaaatcta
    14581 tatacttgtt cccacaatga gtttattaat tggattaatt ttttattatt agttgcttta
    14641 aatatacatt catgaaattc tacatcaagt tttaataacg catctacatc ggattccaaa
    14701 gtgctttttt taaattcttc tgatatatct ttaagctttt taatatcttc atcactaatt
    14761 ctttcagcgg caagatatgc tgctaagcct tctaggcttg ctcttacttc taatacatcc
    14821 ataatatcct ttaatgacat atttgccaca tacgcacctt ttctaggcaa cataacgact
    14881 aaaccttcta attcaagctt tcttattgcc tctctcactg gagtcctact tactcctaat
    14941 tgttctgcta gttgcacttc cattagcctt tgaccaggct ttaattttcc ttctaagatt
    15001 gcttctctta aattctcaaa gactacatct cttaatggct tgtaattatc caagttcagt
    15061 ttagttaaat tctccacaaa tttcaacccc tttttgactg ctattaacaa catacacctg
    15121 tttatatttt tttaataatt ctttttttcc aattagagca tcttctttat ttttaaatag
    15181 tccaaaaact gtaggaccac ttccactcat catagaacct aaagcattat ttttcatcat
    15241 tacttgtttt atatcactta tttctttgtg tttacctata gtaacatttt caagaatatt
    15301 taccatgctt tctgatacag cttttatatc ttcagatttt aaacactcta tcaaatattt
    15361 attatttggt ctttttttaa tattattcaa atctaatcct tgataaactt ctttagtaga
    15421 aacgaataag tctggtttgc atatcaatat atttgtatca catggtaaac ctttgatgtt
    15481 tgttagcttt tctccaatac cttgagctaa ggcaggtctt cctgatatac aaaaaggaac
    15541 atctgcgccc aaattaagtc ctatttcttt taattcatct tcagataatc taagttccca
    15601 taggtgattt aaacctacta atactgcggc tgcattagaa cttcctccag ccatccctgc
    15661 tgctacagga atattttttt ctatgaatat ttctacacct ttttttatat aaaatttatt
    15721 tttaagtatt ttggcagctt tataaacaat attatcttca tctaaaggaa tatctaaact
    15781 agtgcttttt acctttattt catcttcgtc taattctttt atctttacta tatcgtataa
    15841 atctatcgtt tgcattatca tttcaacaaa atgataaccg tcttgccttt ttcccaagac
    15901 atcaatggat aaatttattt ttgctctact ctttagtctt ataaaatcca ttctatcctc
    15961 cttgtttaaa gaataatgca tcactaacaa taatattata ctacaaaaaa taaaataata
    16021 gggtattata ataccctatt atacttaatt actttaaatt ttttaatatt aatctactaa
    16081 tacgactttt ttttctaaaa taagacactt accaggctta attggttcat caagttttat
    16141 atcattaagt tctgcaattt cattttctgt tgtattgtat ttttttgcta tattccagaa
    16201 agtatctcct tctttgcata tatatacgat tatgctagga gctttagata aatcatatac
    16261 accttggtct tctcccttga taataaaatt ttctgctttc ttatctaatg cttcagtaaa
    16321 tctcttaatt ttgataatca agtctatctg gtccctattc aaatcaactt cgactttatc
    16381 aatacatgct gtattaaaca cagatgctgt atcagttaga ttatccattt ctatatcatg
    16441 ttcaaatgga atttcctcac taattttata aaccaatttt aaaccttcaa ctgggacaaa
    16501 taaaatttca acttttatga ttccttgtat aatgctttta tttccttcaa tataactatt
    16561 ttctatagac atggttggac aaacgcttac aatatctttt atttgtatat catcattatc
    16621 atttcttatg ccttctctaa ccataaatgt ttcttcacta cgtcttaaag tcttatttaa
    16681 ttgaataggt ttgtggtcaa attttattat cttttgaggc gaatatgcat cttgtaatac
    16741 ttctcttgta acttcatctg taacttttac cttacaacaa gccatacaat ctatttctaa
    16801 aagacctgtg ttgctttcac tattttgctt gaaaatatga ttaaaatctg acatagacaa
    16861 caatacttct tcagtcatac catcactaac tccagggact tctacaaatt gagtaaactc
    16921 aatacctact ctatccaact ctacaagttc accctcatat gtacaagcta acggatttat
    16981 ttctaatact ccaccaataa taactttatt gtcagtcact ctactttctt ttactttaac
    17041 acatggattt aaacttatta tagattgaat ttcctctgtg tttattgtta tagtatctct
    17101 tatagaactt tctgcttttt ctattccaac tatatcttga aaacaaattt cctttctgtg
    17161 cttttgtatg ccttccactt gcgccacatc ttttacaatg tctaaccttt gcttttcaaa
    17221 caaacttccc cttatattca taagagctcc tactttaatc tttctctcat tcattatagt
    17281 acaatccata tgctctactt ctgaaaataa catgtattcc atatcttgaa caacattgtc
    17341 tttttctatt acttcgttta tatctacttt tccgtctaca ttagaaatag tatttttatc
    17401 atctgcaata tagattacat tataattaaa actacctctg caaagtatct tcccatctgc
    17461 catttcaatt tttttaagtg atatgtatcc ttctgttttt acaatttcat atacatctaa
    17521 ttttttgtct ggtacaactg cctccgcttc aatgaatgtt tgaaattttc caaagtctat
    17581 tctattgtca actttaatta catctttaat taattccata gtctacctcc ttaagtatta
    17641 taaaaatatc acactatatt tatatttaag gagcaaaaaa aaaattacac ctatttttaa
    17701 ataggtataa ttttaactta tttgtaattt atcttgatct ctaaaaactt gcaactttac
    17761 attagatgtt aataaatctg agtaactata agatactcta ggatatccat tactttcatc
    17821 atctaacttt ataacaaaca cgcttggata aactttttct agtataccct cttttgtaat
    17881 aatctgcttt cttcctttat tagctttcaa caatattttc tttcctatat gtctctctaa
    17941 gcttactctt atcttatcta gagtttgaac agtagccaca atatcacctt ctttaacgtt
    18001 tatatgttta cataatatca catataaaca tttttgtcaa atgtttaaac taattatttt
    18061 atatattttt tgcaaaaatg tcaatactat ttttgaagat atacagtata attatgttaa
    18121 tttttgctaa tgtaatattg tttttggcat tgcccatcta aattttcctc tggtttcaga
    18181 accaccaatt cccttaacac ctgtaatagt ctgctctata acctcatcaa taggaactac
    18241 tacatcaatt cttgaacaag caattttctc cactataaaa acagggtcta atgcatgtat
    18301 cattatcctt ccaggcgaac ttgcatagtt tgctcctgca cttattattt tttcataatt
    18361 tgattggcat gctcctgcga atatgacaag attatccaaa tttggttgcc atttacgtgc
    18421 ttcttttact gttttaacaa aatttgaaga gtttctatag ttactcatat cttctatatc
    18481 tcctcttttt attgtcattg catcatgacc tgttattact agtatatccg gattatattt
    18541 ttctagtagt gctcttactt ctttatactg attttgctct gaaacagcta cacctactgc
    18601 aggtattcca agttgagcat atacatccaa gcaaattttt aaatattctt tatctccatc
    18661 tatctgtagt acttttccag gcattccata tgtgttagga tttaattgaa gttttggaac
    18721 tgctctagtc attctttttt gtctttcttt agcttttctt actgacttat ataataaatt
    18781 ttctacattt ttatctatta atatatcttt tatatcaggt gcttttacta attctaggtc
    18841 atcaatataa gcatctgcta ttactctaaa tgcaattccc tttagtatag ctattttctc
    18901 attattttca tctacaccaa aagagactat tttaaatact atatctttgt tatgtgactt
    18961 tctagctaca atgtctccta ccttcatagt taaacctcca ataaattttt atcttagttt
    19021 atactatgtt cgatataaaa ctttgtttcc taatgtcaaa aaaacatttc ttataatact
    19081 tcttttatca ctcttaaagc atttttatag tatatctttt ctatatcatc ttcactaaac
    19141 ccttcttttt ttagaggttc atacagttta cccatctgag atatatcttc aatctcaact
    19201 tttgaatcta ttccatcaaa atctgaccct agagatacaa catctattcc tccaacattt
    19261 acaatatgtt ttatgtgtct aaccatatct tcaagtttac tttcactttt atcacttaaa
    19321 aataagtgga agaagtttat acctgtaact ccacctttat ttgctaatac tttaatcata
    19381 tcatcagtta aatttctaga atgattcatc attgctcttg aattagaatg tgtagcaatt
    19441 attggtttag aagaaatctt tgcaatttca taaaatccac catctgaaat atgagaaaca
    19501 tcaaccaaca ttcccaattc attcatctta tgtaccactt ctcttccaaa atcagtaagc
    19561 cctttttctc tatattctac tttattatga ggaaagctca attcattcac atgattccaa
    19621 cttattgtca tcattctaac ccctaagtcg taaaatttct ttaaattttc taatttacct
    19681 tcaagtactg caccttcctc aatagataaa agagctgtaa gtttaccttc tgattggttt
    19741 ttcataattt cttcatagtt agtagctaaa gctatttcat cactattttt tttcatttcc
    19801 tcatgaaatt tatttgccat actcatgcaa taatcaaaag gatgttttac ttcttcagta
    19861 tcaacaaaaa gagcaaatgt ttgagctaat gaatccccct ttttcaatct gtctatatca
    19921 acagaatatt tattagactt aagttcactt gtttctacat tttccattaa ttttgctata
    19981 gtatcacaat gtaaatcaat aaatttcata tttatacccc ctgtatattt tatatttata
    20041 tctaaaaata gaaatagttg tccttataga caactattga caactatttt ttaatattct
    20101 ttttaatatt acttaatctt attcttcttt taagttaggt attacttttt taacttcttc
    20161 aatttgatgc catgttttat ctatattatt ttcactaata tattttttta aatcagttaa
    20221 agatgtaaaa tctttaactg ataaattgtc atcatcatct gcaaatctta aaataaacat
    20281 gagactccct tactttccac aacatttctt atattttttt ccgcttccac atgggcatga
    20341 atcatttctt cctatttttg cttctttaac tattgtttta gacttcttat aagcctttat
    20401 tatttctttt ctttggtctg ctggtagtat atcttcccaa ccttgtaaat tatatagcca
    20461 atgagcctca acagttacca tattgttata taatttttcc caatctattt ttatagaaac
    20521 ttctttatca gcttctactt cttctaaaac tatatcttct tttaagcttt cacttattcc
    20581 atctatgaat cccatgaaaa attcattagt agttccaaat ttttcagcca attcacttac
    20641 tttaccttca acaacatcca ttttattatt taatatttca ttgtatattc cagcttcaac
    20701 tttcaaatat tcttcccaga attttacttc tgcttcttga ctttcatgat tatcacttaa
    20761 atttctccat tcagtatata aactcatact ttttcctcct aagtatacct atatttttat
    20821 agtttttata gtataaaatc ttttagttag attggaagtt tcttcttttt gattatacca
    20881 tattctattt aaagttaact cttatattat atcataatta aacaattctt ttaatacttt
    20941 tatagcatac tcttggttta taaaataagg gcttgtcgca attgttatta ctttggcttt
    21001 tttaattaag ttttttatct tgtaaaattt gagttcaaat ggtatatagt ccatatcact
    21061 tgaaaatata tccaaatcta tgtcaagaac aaactctgat tctacttcta aatcaaatcc
    21121 atatagacta tctattatta ttaattctga aaatatgtta tattttaaag caggttttat
    21181 aaaacttccc acatttaaaa cttcatttgt atatctaaat acatctttta gattatttac
    21241 atctacatca tagttctcag gttctctagt atccttatgt tggtctacat gcactaactt
    21301 gcatcctttt gtaaactcac cctttaacaa agactttgcc caaaaataaa atgcatggtt
    21361 atgattgtca aacacatata tctttttatt tcccaggaca tattcgacca tattctccaa
    21421 tccttttgct tttatttcct tattttcatc tacttcatta aatactacct cattgcctaa
    21481 ccttacatca tttaatgtac catttataag ttttggaacg tatatgctct tattttctct
    21541 tttatcatat gaaaatacat tatttcctac tggtttttct atataaaatc cactatattc
    21601 ataattttcc ataaaacttt atttcctcca ttgttatata aatatataag ttataatttt
    21661 aaaaattaaa atgcacttat tgtaaatcat atcatctatt atagaaaaca tcttatataa
    21721 ctaaatataa tatcttctct caatatgtat tatacaataa gtgtaaaata tatttatata
    21781 aaatatacta cattcctata acaaaaccat cagcttcaat tggaagataa ctaactcttc
    21841 tattcaactc cacctttcca aaaaatacta cccaatatgg tctaaaaata ctttcaattt
    21901 taactatttc aatctctggg attcctccca taaacctatg agttaatctc atagccattt
    21961 tatttgcctt tgcttttact cttcgttcgt ccttatcact atactgcaca atattacaat
    22021 ccacattttt tacaacttca tatgtaggaa aatcttgtac tatactacca gaacctgtag
    22081 aaccattcac taaaattttt aattcattta tatcattaga atatctccta ttcttgaaaa
    22141 tggatttcgt tttgtgaatt ttaagtgtga taattttaaa ctctatataa tgaagtctaa
    22201 cttcatgagc atatttgttc tttaatatta gcttactaaa taaagaattt tttccacttt
    22261 tagctatctc tatagcttct tcttttgtaa ttcttatagg taacgctctt atatccataa
    22321 aatcattctc tttcttattt ttttcttgtc atttttaaaa ctctatatat ataatcaaaa
    22381 aatattacaa ttacaactga cataactcca tatggaatta tttttccaac tataatatca
    22441 tttctagtca atataccata aaatataaat cctgttatta aaaagtacaa taatactaga
    22501 aaaccgtcta ttccaagcca ttttatttct aaatcttttt ttaccttaga cactaattta
    22561 gacatagcag tttctccttt tatagattat tttgtgtatt taaattttca cctattctat
    22621 taccaatcat ccatgcaata aatgaaaaag gtatagctat cacaagaggc tctaactcaa
    22681 agctctgaac tggaaatatt ttaaaataac caaaagtcac tccaccaaca atcattccta
    22741 aaataccacc catagatgtt cttcttccat ttccaagaag cccacctact ataggtacaa
    22801 atgccgaacc catccaaata cttcctacaa atatacatgc atcatataca ttttcaaatc
    22861 taaatgctac gctaagcccc ataactgctg ctaaacatac acctattcta gtaaacttta
    22921 ctaattgttt ctgagataac tctttttttg taattcttcc atatatatca tttgctaatg
    22981 tagccccagc tgctagataa tagctatcca atgttgatat tatagaacct aaaattccta
    23041 ttataaatat tactcttatt ccttgtggta atgtatctaa aactaaagtt atatatccag
    23101 cagctggagc catttctgga taagtagctc ttactataag tcctgtcata gttaacacca
    23161 tgtcaaaaca tatccatagt gaaaaacagg ttaataaggc tcttcttcca accttaggag
    23221 aatctgctgc tgaaaatctt tgataaaaag ttgggtctga ataagctcca aaagaatata
    23281 caattaacat caatgctttc atagctgaca taccctttgt agggtgcata agctgtggtg
    23341 catctttgag tgcttctgta agaccttgaa accctcctat ttgttcaaat tgacctggca
    23401 taaccatagt taaaccaaat accatacaaa aaaacaatac catatctgta atggcaactc
    23461 ccataagccc accaagtact gtaagtacaa cgactactcc taccattatt aatcctatta
    23521 attctttatc tattttccat gctacgttac ctatagttcc catagcagtt atttctccaa
    23581 gttgtgcaca atatataaac atcaaaattg ccccaattat agcaacatgc ttgccataaa
    23641 aactttccag taaatcagga actgttatat tggttcttat atgaatcctt ggaccaaccc
    23701 acaatgctaa aggcattctc ccaatatgtg cagctattga ccaaactgcc catgcagata
    23761 ttccatatat agccgcatac tctacactac ctactgtacc aactcctcca taccatgatg
    23821 caaccaaagt tcctactatt aaggaccatg gtaaacttcg atttcctagg taataacttt
    23881 ccatatcttt tacatttcta gaaaaataat aacctattcc taataatata aatgcaaata
    23941 taactataat cccattttcc caaaatgtta acatatctaa tctccacatt cttatatttt
    24001 aatttttaac tttaatatct aaatatgaac aactctaccc atttccataa aaataggtag
    24061 agttatataa taattataag tatttaagta atcttgttat taagcaattt tattgtttaa
    24121 acctttattt tctcttttat ttattttatt taaagcataa gtagcaaata tccctataac
    24181 tgcacatact acagataaaa taaatatata tgtatatcct gtttgtccat atttatctaa
    24241 ccaattacct gcaatagtgt aataaaacgc atctggagaa aatcctataa atgaagcaaa
    24301 tccaactact gctcctgtag tttctaaaga tatattagac tctgaaacag atgcaaagta
    24361 tatacctcta aatccaaata aaattacact tagtattatc atgtttatta cagctatcca
    24421 tataaatcct gtactcttag gaataaccaa gtaagcagct gtacttactg tcattaatat
    24481 aaatcctaca aacattactc ttatagatga accaacttta tctgttataa caccagcaac
    24541 tggagatgct cccattttta taacataagt tcttattatt gataaagcag aaactagagt
    24601 cattggcatt acataaactt ctgataagta tggacttaaa taagttaaac ttgagaatac
    24661 taaataagtt gaaaatatta taagaccaat tagccaagcc tttggcattg taactacttt
    24721 taacaatgac ttaatactta atccttcatc tgatgctcca ctatcttttt tctcttccac
    24781 taagaaaaat agaagtatac cacatattat agatgctgca gaatataacc atactacata
    24841 tttgaatcct actgttattt cagcaaattt accaaagaag taaagaccta taaaagaaat
    24901 taatgtacct gatacacctg ataacccttc ataaaaacca aatattcttc cttgctctga
    24961 ctcacttcct tgcattctaa caaccttaac agaggctgag aagaaagtta atattgttgt
    25021 aaatccccat aatacaaata ttaaaagtat catactatat gatgggaatg tagagaaata
    25081 aaatccaagt attcctgaag caattaaaga aaaagttatt aattttctaa ctgagaatct
    25141 atctgcaaac catcctccta taaaataaga taccattcct actaatccat ataaactcaa
    25201 taagttccct atttgtgtat gacttaatgc taaagcttgt tgcattgggt cataaaatga
    25261 tgatttcata tatggtaaac tatacatagc tgttgttcca aatgccaata tgaatattat
    25321 caaaaatctt ttaacattat ttttgctttc cattgattct ctctccttaa aattttattg
    25381 tttataatct cattcatata attttatttt aatttttcta ttgcttgttt aaaatcattt
    25441 attatatcat ttgaagattc taatcctaca gctattctta ttagattttc cccattcatt
    25501 tgaactaatg tatgctcttc ccctaagctt gttgctattg ttgcaagctc taaagaattc
    25561 attaatcttc tactagcttg gtctcttgtc aatccattga taccatcctt aagtttaaat
    25621 gaaactacac ctccacctaa accattcatt tgagttttac aaagctcata ttgaggatga
    25681 gattttaatg ctggatactt taccaattcc acattctctt cttcctctaa aaattctgct
    25741 actgctaatc cattttcaca atgctttttc atcctcatat ctaacgtttt catacccctt
    25801 aaaatcatcc atgcactcat tggtggtaaa gatgctcctg taaaacaaca taaacttggc
    25861 catctaacta aatctattaa ttcttttgaa cctgctactg ctccccctaa agtatcccca
    25921 tgtccattta taaacttagt aagactatgt attactaaat ctgcacctaa atctattggt
    25981 ctttgtacaa ttggtgtccc aaaagtacta tcaactatag ctaagctttt attttcatga
    26041 gcaatttctg ctattgtttt tatatctact aagtctaatg atggatttaa aggactttct
    26101 atataaacta ttttagtatt tggtctcatt gcttctttta cattttgtgg atttactgca
    26161 tctacaaatg taacttcaac tccaaattta gataacaact cagacatgaa taatttagtg
    26221 tgtgaaaata ttccatctga actaactata tggtcaccac tttttaccaa tgctaatata
    26281 gtagatgtta ttgcccccat ccctgatgta ctagatatgg cactttctgc attttcaagc
    26341 atagccaact tagcttctaa ctctgtaaga gtaggattac actctcttgt atacacatat
    26401 ccccatgtca tacacaactc ttcaaaatgc tctactgtct ttgcagcaaa tgttgctgtt
    26461 tgacatattg gtgtagccaa tgcacctgtt gttgggtctg cactatgtcc ccaatgtatt
    26521 atttttgtct ctaaatcttg attaatattg ttactcattt tgatttcctc ccattttgac
    26581 ttatttatac aacgttttcc ctaccaaatt tcatcaattt agcttagtct taatacattt
    26641 tttcaagtat acttttttat ttgttataat ttctaaaaat atgacactta ttttgttttt
    26701 ttacagttct aattataaac tctatagtaa ctatagagtc aatatgtttt tgatattttt
    26761 tttacaatgt ttaaaatagt cagtacaaaa ataggtatat cttagaataa ctaaagtcat
    26821 cctaagatat acctattttt atatcacaat ataaataatt acatataagc attagttttt
    26881 ttatcataaa tagatttttc aagatttatc atcttttcat aaatatatta tagttaaata
    26941 ttttaatatt acctaacatc tacaataaaa tatactctta aaataaaatt atataattaa
    27001 aaatactcta taaaagctaa aaagtttttc tattcgctac atctaaaaat aattagatag
    27061 aggtataaat gtatttagtt tatttatacc tctagtcttt tataaattat atctctacta
    27121 aattgatttt ttagcacgaa taagtgtgct cttggagata ccagtcatct tcacaacctc
    27181 tctatatggc ttagaattta ataaccccaa tgcatattgt atctgttgat tgctgtattt
    27241 ctttggccta ccatctttaa agtccttttt ctttttagca aattcttttc ctaattgagt
    27301 acgttctatt atcatatttc tctcaagttc tgcaactgca agtaatgtag tcaaaaagaa
    27361 tttacccatt gaagtatttt ctaaaaggcc tatatttaaa atatgaacac ttacttcttt
    27421 agcaaataaa ccttctatta gttgtattcc ttctgatgta cttctagcta gtctatccag
    27481 cttagttgca acaagtaagt ctcccttttt tagagatgat ataatttttt caaatttagg
    27541 cctgtttgta gtagtgcctg tataagtttc ctttattatt ttagcatcat tatatttatt
    27601 caaaatttct tgctgttgct gatacaaact gttgttgtct gtttgatttt ttgtacttac
    27661 acggcaatat ccatatataa taatcatcac ttcctaacat aaagattttg tacagaagtt
    27721 acccagaagc ttgtttttac ttatctttat ccattttact aaaacgattt ttgggtgtca
    27781 atactgttaa cttttgacac cataataatt cctttataat ttgtttgact atgtcaaaaa
    27841 ttaccaatat aatgaaatta atgagtttat acaaattgga ggaaataata tgaatagtct
    27901 gttaaaagaa gcaatagatg aattaaaaaa catccattgc ggggaagttt ttttattaaa
    27961 agaattgttc aaaggctatg aatggaacag gttggagatg aatatcagat tgaaattagg
    28021 aaaacttttt ttgtatgaag tggtaactaa tcccaattta aatgtagagg tcatcaataa
    28081 aaattctgct tatcagcaaa tgtataaaaa aaaatagtga cttaaatgta tataatagta
    28141 taatcttctt attgattcaa aagttaaaac ttttaataca aaacaatcat tctattttaa
    28201 catttatcaa tatgtctaaa tttatataat taacacatac gaatagtatt gtttaaatca
    28261 cattatttaa gatagataaa tcttaaccct actccagcat aaatactaaa atagggctta
    28321 gaattatcta tatttttatc ccataaaatg cttagctctt cctcttgatt gaacatatat
    28381 atctggggaa atacaataga agcgtaaatt tataaaattt ccaaagtcag aaaacttcag
    28441 ttcaaactta ggtataccaa aactttcagg tgctatttcg tcaacgccaa aatagatgat
    28501 aattccatta tctgtaagat aaaatgcttg gtcttcaggt ataactaact caacattaga
    28561 ataatacatt tctctatttt catttatttg agatttaatg taatcagtaa ttatattaat
    28621 ataatcaact ccatctctaa aaatgtcatt aagtaaaagt tcttttccag ttgtcaaatc
    28681 tatattgtaa ttattcaatg tattgtattt aggcccatag ttattagcaa accccataag
    28741 gtttaatatc atactcagta cataattttt attaaaagta actgcgtaac tggtagatac
    28801 ccaatagctt tgttttggaa gtgaattttg agaagttgcg ttattatatt ctcgttcttc
    28861 ttcctgtaag ccatttttaa aattatttac agtcattctt acagcattgt ttatgttatt
    28921 taaaataact gggtttacat acgtggattg atttctaata ttgtatataa caggatactt
    28981 tacatcatat gaaaaatact tacttctttc aaaatcttca ttaaattgta catataatat
    29041 attatatgta caggtatttg tagattgata attttccatt aaaatcctcc cccttttata
    29101 aaaaaatcag atacaatata atatgcttaa aacagtaata atgttaatgg taaatgtaaa
    29161 gaatagaaag tatctaaaac agcaaaaaat gactaatttt gtggtataat acataggatt
    29221 gagagttatt ttataggagg aaaaatatgt tattattagc agataaatgg aaagattatg
    29281 aacttataga tatgggaaat ggagaaaaat tagaacgttg gggaagttat gtacttagaa
    29341 gaccagaccc acaggttgta tggccaatgg aatctgaatg ggctttatgg aaaaaccctc
    29401 atggacatta tcacagaagc aataaaggtg gaggtcaatg ggaacacaaa aaaagatatc
    29461 cagaacaatg gactataaat tataaaaact taaagtttca cattaaacca actggcttta
    29521 aacatactgg attattccca gagcaagcag ctaactggga ttggatgata gagaaaataa
    29581 agaaagctaa cagacctata aaagtgttga atctttttgc atatacaggt ggagctactg
    29641 tagcatgtgc atctgctggt gcagaagtat gtcatgttga tgctgcaaaa ggtatggtta
    29701 attgggcaaa agaaaatata gaattatcag gtcttaaaaa tcaaacagta agatttatag
    29761 tggatgatgt tgtaaagttt gttgaaagag aaataagaag aggtaaaaaa tatgatgcaa
    29821 taataatgga ccctccttct tatggaagag gtcctaaagg agaagtatgg caaatagaag
    29881 aaaagttata cagttttgta gatttatgta tgggagtttt atcagataac cctttatttt
    29941 tcttaattaa ttcttataca acaggatttt ctccaatagt tcttgaaaat gtattgtcta
    30001 caacaatagg taaaaagaca aatacaggag atatatacgg tggggaatta ggaataccag
    30061 cttccagaga tggtaagata cttccttgtg gtatatttgg aagatgggag aaaaaataat
    30121 gataaaagtc atatatgaag ataaccattt attagttgta gaaaaaccag ttaacatatt
    30181 gtctcaagga gataatacta atgataaaga tatggtaaat cttttaaaag actatattaa
    30241 aaaaaagtat aacaaacctg gaaatgtata tattggttta atacatagat tggatagacc
    30301 agtaggtgga gttatggtgt ttgcaaaaac atcaaaagca gcatctagat tgtctgagca
    30361 ggtaagaagt aagactttca aaaaaactta tctagctgtt gttcatggca agataaaatc
    30421 taactcagat atactaaaag attttttata taaaaataaa aaaactaata tggtaactgt
    30481 agtgaaaaaa agccataaag atgccaaaga agctgaactt aactataatg tattagattt
    30541 taaagaaaat ctaagtttag ttcaagttaa tttaaagact ggtcgttctc atcaaataag
    30601 agttcaattt gcaagcagaa aacatccatt atacggagac caaagatatg gcaaagaaat
    30661 aaataagatt ggacaacaaa tatctctttg gtccaataag atagaaattt gccatcctac
    30721 tacaaaagaa aaaatggaat ttacatgtca tccacctgac aaatatccat ggaatatatt
    30781 ttaaatctca aatgaggtga ttatatgagt aaaaaatttt caataggaga aatgtctaaa
    30841 cttcataaaa taagcataca gacactaagg tactatgacc aaatagattt atttaaacct
    30901 gttcatgttg accaagaaag caattacaga tattactcaa ttgaccaatt ttcacaatta
    30961 gatattataa aatatttaaa atatttaggt atgcctttaa aagaaattaa gtcaaagctt
    31021 gatgaaaata atgaagaaat tctaaaatta ctaacaaata aaattaatat agtggatgaa
    31081 aaaattaaag aattagagct tataaagaag gtactaagca caaagaaaga aactatggaa
    31141 aaaggtatga aagtagatga agttggtaaa atagtgagaa aacatattcc acgaagaagt
    31201 atcttatcta tagagtatga agaaggatta agtagtgaag aaactatgga actttccaga
    31261 agacaaatag caaatatatt agaagataat atatctgtgt tctatggtgg agtaagtgga
    31321 cttgtatcta tagataaatt tttaaaagaa gataaagtta tttatgacaa tagttttgtt
    31381 actgttgaaa gagacttatt tgatataaaa tcacaaaaac atataacaga aatttcatct
    31441 ggtgatttta tttgtatgac atataaaggg ccttacaaag aaaattatac cgcttttaag
    31501 aaactggttg attatgttga atataaaaga atacctattg aaaattatat atatgaaata
    31561 cctataatag accctctgtc tacaaacaac gaagaggaac ttctaacaga aattcaaata
    31621 caagttaaaa agagagaaat tgacttaaga tgtctagtgt agtaatctag tttacttaca
    31681 catcttaata tagttgtcta ttatcaacat atgatttttc tagatagtga ttcctaacag
    31741 tgagattttc aaaaaatagg aggaaatatg gctaatgcta attccctcct atttttaatt
    31801 aagccatatc attttaatta agccatgtca tcacgaagtg catcaataat attttctttt
    31861 tttatcttat taatagtata caacattgta ataaatacta taaataaaac actaaatata
    31921 ctaattccaa tactaaacca tggaatcaca aaatcaatat catctgtaac cattacttta
    31981 tgaattagcc atgaagaaat tactgctata ggaagtccaa agaacaatgc tctcatgcca
    32041 taaaaggcac actcaaaatt catcatcttt tggaaatcat gctcagacat tcctacagag
    32101 cgaagcatgg caagttctct acgacgtaac ttaatattag ttgaaattgt attaaacaca
    32161 ttggcaatcg aaatcagaga aatcataatt atgaaagtat aagcaaaaac attggcaata
    32221 aaaatgtaat tacggttctc atccatcatt ccatacatat tgtacagatt gtactcattc
    32281 gtaactccct cactctcaat aatttgctcc atttctgcaa ctgactgagt aggatttttc
    32341 gattgaaagc ttaaactttc aattcctgta gaaacaccag gaatctcaaa cttatctttg
    32401 gctgaataag gagccaatac tctgaagctt gctttcttca catctgaact tctgattcct
    32461 ggaggagaat caggtggcac tactttgaca aatgaaatat tcacattttg tctctcaggt
    32521 atctccaact tgccattagt ttcaggagtg aggctaacat tcatagaaga actgttgaaa
    32581 atatcaataa tattattatc ctttgttacc atagaaacag caatcagttt tgcattttgt
    32641 ccagtatatt cttctgctgg taatccaaga cttttaataa tattcagata agttctatca
    32701 tcaagaaatt gcatatctac tggtaattca agcatttcac tcatagaatg tgaaccctca
    32761 tagttcaaat aatcgtctgt aagctcactt actttggcaa cacatgaata ggtcataagt
    32821 ttctgataca aaccttcgta aacaccattt gcagttttta gcttatcgta aagcttcaac
    32881 atttcgttgt ctttcatacc ttgtgtagaa aaaataatat cctggtcagt aacctctgac
    32941 ctctgatttg acatctgttt taggtctgct actaaagcac ttgtagatat aaatagaact
    33001 atgcttaaaa caagcgacaa tacaatactt cgataacgtt tcttgtttct tttaaagttt
    33061 ttcatagcaa gaactccctc aagaccataa actcgctgtg ttagttttga tgtcttcaca
    33121 gatttagatt caatttttac ctcatttgtc tgacgaatac actccatcac tggtgtgttg
    33181 gcagcctttc ttgctggtat gtaagcagaa attaagattg taaccatact taccactgct
    33241 gcaacgatga ttgcagggat agacaatgtt aatgtcaacg gaacgtttac atagagaata
    33301 tttgcaaagt ttttagctat gacagaaatc acaagtccaa tactgactat accgattgca
    33361 acaccaattg gtataccaat cgcaccaatg caaattcctt caaatagcac cgaatttcgt
    33421 aactgttttg ctgtagctcc aacagatgaa agtattccaa attgatgtgt tcgctcgttc
    33481 aatgacatgt taaatgaatt atatattaga aaaattgagc ctagcatgat tatggcaagc
    33541 acaatgccac caaccgagta caaaaacata ttgaacaaat tgttatcaga aacacctatg
    33601 aagcgcaaca cattgtcatt gaaaatggaa gcatggtctt tagtgctact tatgtaagag
    33661 cgaatctgat gtggattttt caatgtgaca aaaaggctaa gactgtcagt cttgacttgt
    33721 ttatcttctt tggttatcaa ggtatatcct ggtgcagaag attcttcaaa tacgggcttt
    33781 ctacagatac ccacaactgt ataagttttc ttatcctgtg gcacaaaaac ttcactccca
    33841 gcagtgtatg ggtcactctg accaagcttt tcattttcac tcattcgttt ccctacatcc
    33901 aaagaaatag tatcacctac tgcaaatttg acaccaccat ctgtcgcaac tttacttgaa
    33961 acaagaatct ctctactatt ttcaggtaat cttccagaaa ttaaagttat aggcaaagta
    34021 tcaaaagctt ctttgctaaa tccagcaata aaaagatatg gtttatctgg atttctgtta
    34081 ccttcaagtg ttgcatagcc aatattttca aatgttgcag tatttgcaac ttcatcattg
    34141 actctttgtt cctgtacaaa agaagaatcc acatccaaaa actggacatg ccaatcacca
    34201 tattttataa tagctccatt tgtcatatag ttcatcaaag aaactccaaa ggtagtaact
    34261 gctgtaatca tagcagctga cagaacaact cctataattg ttacaagagt tcgagtgcga
    34321 ttctttttca atccttgcag agcaactttg ttaaaaatgt tcattaacga ttcaccttcc
    34381 tctcatcacg cactactttt ccatctgaaa tacagataat tctatctgcc tgtaaagcaa
    34441 tgttttcatc atgtgtgaca ataatgagag tttggtgata tttactatgg ctctctttca
    34501 gtaactggat aatctcttgt ccatttttac tgtctaagct acctgtaggc tcatcagcaa
    34561 gcataactgc tggtgcattc atcaatgcac gaccaatggc aacacgttgc tgttggccac
    34621 cagaaagttg atttggtaaa tgtgtttttc gttcttttaa accaagcaat tctaacaagt
    34681 catttaaccg ttcttgattg accttacgct tatccataag tataggcaat gtgatatttt
    34741 ctactacatt taatgtgggt atcagattgt gaaactgata aatcaatcca acttgtcgcc
    34801 tacgaaaaat agcaagtttt tcattgcttt ggccatatac atcttgcccc tccagatata
    34861 tctttccact tgttggtacg tctactcctg caatggaatg tagtagtgta gatttaccag
    34921 aaccagaaga accaatgatt gcagtaaact ctcctttttc aatagtaagt gagacatggt
    34981 caagtgcagt aaccttattt tcattcttac cataaacctt acataaatct tcaatcttta
    35041 aaaacgccat tatataagtc tcctttcata ttttataaat atatcatagg actttcaact
    35101 tacatttaag tgacatttaa atgagagatt cgtcactttg gaaaacgaat aacaaatatt
    35161 gcaccacctt gtgggtgatt ttgtgcagta attgttcctc cttgtctcat aataatcgtc
    35221 ttacaaagtg ccaatcctat tccataaccg gctgtgcttg aatttttccc acgataaaat
    35281 ctgttaaata gacatggtaa atcttctttt ttaaagcctg ctccgttgtc atgaatagta
    35341 agttgagtaa acaaaaagtt gtcctcacaa atgatatcaa tttttccatt atcacccaca
    35401 ctctccatgc agtttttaaa tatattttga attgcttctg aaagccaatt taaatcaccc
    35461 aaaatcctta ctccttttgg tatatcaata tgtaaagtga tattgtgcag ttccatggga
    35521 atcaaaagtt gatgaagtgc agaactaatc aaattattca catcaatttg ttctttttga
    35581 aagactacaa tacctgcatc taaacgtgat aattttaaaa gggaagtaat cagccagtcc
    35641 attcgtataa gtaattcctc tgtttctcgt atcaactctt ttctctcatc ttcatcagaa
    35701 gtattctcta acagtgacaa aataagagtt actgatgtaa gaggagtgcg aagctggtgg
    35761 gctatgtcag ctagtgagtc agcaaggtgt tctttttctt ttttcaatgc gtaattttgc
    35821 tctctaatac gtaacgtcat tttagttatt tcactttgca gaatagaaag ttcaccctca
    35881 tctgattcag caatatacag atggttagca ttatgaagca caagattaat ttgttctgaa
    35941 atctgtgcaa tacttttgta tcgattttta gtaaacacaa aaaatgctat tccaaaggta
    36001 gtggcagaaa caatagaaag tattccagtc ataatactga ttgcaaatcc cagggctaca
    36061 gtgagaatag taattaataa gaataaaata gcaaattttc gaaactctct atttcgaaac
    36121 ataacttccc cccaatctat accctgtccc acgaacagtc aaaattattt gtggacttga
    36181 agggtcatct tctatcttct ctcgcaagcg tttgatgtac acagtcaatg tgttgtcatt
    36241 aacaaactca cctgccgcat cccacaattc atcaagtaat cttaccctcg taataatact
    36301 tttaggattg ctaataaaca ccaataacaa acggtattct aaagctgaaa gaaaaacctc
    36361 attgccattc tttttcacaa caccggttgc cgtatctaca taaagcccac aaatttcaaa
    36421 agttgaccca aaacgcccac tttttcgtag tgctgttcta attcgcgcaa tcagttcacg
    36481 tggacgaaaa ggtttagtaa tataatcatc tgcacccata ttcagtccag taacaacact
    36541 tgattcatca ccggaagctg tcaaaaagat aacaggaatg tcttgctttt ctttgatttc
    36601 tgtgcaaatc gtaaacccat ttccatcagg taaagaaata tcaataagtg ccaaatcaaa
    36661 tttattctta gcaatctcta caagtgcttc acttcttgtg gatacatggg ttactataaa
    36721 tccttctgaa ttaagcaaaa gaataagatt tttggcaatt gctttatcat cctcaactaa
    36781 aaatatccgt ttcatttact ttcatcctcc tttattttat tagttttata tattccagca
    36841 gagcaatagt acactactat tttacttatc attacacaat tttcagtagt ttcttttgtt
    36901 cttatataat ccatgcataa tacctccatt gatttattat atttcttata acataaatac
    36961 acaagataag acaaaaaaca taatgtaagt gcaagttttt taactcacta acttataaac
    37021 atacactcct actaacacta ctttcttgat gacacatctt acaagcttat attcatacat
    37081 caatgaaaaa ttaaatttat ccatttatta aaataaaagg caatagcttc tatagctaat
    37141 gccctttatc ttaaaatgat ttaaatacta tacaattttt ataaatggct ataaataaac
    37201 tcgtatagaa tataaaattt atctacagtc ttttgttata caaaatttat aacctcttat
    37261 agaacaaatt taccactttg caaacttatc acttttactc agctatatta taaactttta
    37321 atttatcttt gtttaaatgt ttcttcttaa cttctactaa agcttttagc gtatccaaag
    37381 atgtcattat ttcagtagaa aattcaatgg ctgttcttct catcttaaat ccatctcttg
    37441 tagagtcatt tcctttagtt ggtgtattta ttactatatc aacttgttta tttcttatag
    37501 catctaatat gtttggtcta ggctcttcaa ttctatttac tatatcagcc tctattccat
    37561 tttctcttaa actcttcgct gttccttctg tagcaacaaa agtatatcct aattctttca
    37621 tatcttttgc tatctctata aactcatctt tatcatgatt atttacagta gcaagtacta
    37681 ctcctctttc atcagacata tgtctacctg ctgccaagaa ccctttatat aaggcttctt
    37741 ctaaattttc tcctacacct agaacttctc ctgtagactt catttcaggt cctagactta
    37801 cttcaacttt agataattta gacattgaga atactggtac ttttactgat actaattttg
    37861 gctctttgta aactcctgta ctatatccta aatcctttaa tttagctcct aacatacact
    37921 tagtagccaa gtcaactatt ggtactccac ttactttact tatatatgga actgttctac
    37981 tagctctagg gttaacctca attatatata attcattttg aaattctata aattgtatat
    38041 taaccatacc aagcacatta aggtctaaag ctattttttt agtgtattct actatttttt
    38101 cttttatttc atcagatata ttttgacttg gatacattgt tgtactatct ccagagtgaa
    38161 ctccagctct ttctaaatgc tccattatac caggtatcaa tatatcttct ttatcacata
    38221 tagcatctac ttctatttct ctaccagtta gatatttatc tataagtact ggatttttat
    38281 ggtctctatc aaatgcatca tccaaatact gaattagttt ttcttcgtta taagttattt
    38341 ccataccttg accaccaagt acataagatg gtctaactaa tactggataa cctaactcct
    38401 tagcaatttc aacaccttca ttagttgtcc atacaccttt tccttttggt ctatttatat
    38461 ctagtctctc tagtaaatca tcaaattttt ctctatcttc tgctgcatct atatctctaa
    38521 agtctgttcc cagtataggt atattttttt catgtaaaaa cttagccaat tttatagctg
    38581 tttgtccacc aaactgtagt attacacctt ctggtttttc tttttctatt atatttaaaa
    38641 cttcttcttc tgttaatggt tcaaaataca acttatcaga tgtatcaaaa tccgtactta
    38701 cagtttcagg gttattgttt acaattatag tttctattcc catttttctt aaagatttta
    38761 cacagtgaac tgaacaatag tcaaattcta ttccttgacc tattcttatt ggaccagaac
    38821 ccaatactac aacttttctc ttatcactaa ctactacctc atcatattgt tcataagttg
    38881 aatagtaata aggtgataga gcttcaaatt ctcctccaca tgtatcaacc attttataaa
    38941 ctggttgtat attatataaa cttctcaatt catataattt ttctgggctt atcttcatta
    39001 agtcagatat acctttatca gaaaatccct ttttctttaa ttcatgtaaa tattctttat
    39061 ctaagtcttc tatttttaga acttttaact tttcttcttg ttctactatc catttaaatt
    39121 tatttataaa ccacttatca acaccagtta tttctgatat catttctact ttatagcctc
    39181 ttcttatcat ttcagctaag tcaaatagtc tctcatcatc aggtactact actctagcct
    39241 ttaattcttc taatgttcta ccttctgatg gagcatgaac caatgaatat tttcctgttt
    39301 caagtgatct tataccttta agaatagcag cctcaaagtt acttcctata ctcatgattt
    39361 caccagttgc catcatctta gttcctaatt ttctattggc atgtctaaat ttatcaaatg
    39421 gccactttgg tatttttact accacataat ctaatgttgg ctcaaaacaa gcataagttt
    39481 ttttagttac tgcattttct atctcatcca aagtataacc taaagctatc ttagctgcta
    39541 cttttgctat tgggtatcct gtagcttttg atgctagggc tgatgaccta ctaactcttg
    39601 gatttatttc tattatcgca tattctaaac tatgtgggtt taaagctatt tgaacgttac
    39661 atccaccttg aacctctatt gcatttatta tgtctattga tgcctttcta agtagttgat
    39721 actcttcatc acttagagtt tgacttggag caacaactat actgtctccc gtatgaactc
    39781 caactgggtc tacattttcc atattacata cagttataca gtttccattt ccatccctca
    39841 ttacttcgta ttctatttct ttccaacctt ttatactctt ttcaagaaga acttgtccaa
    39901 caggacttag ctgtagtcca tgtgaaagta tttctcttaa ttcttcctca gtatcagcta
    39961 tacctccacc agttccacct agcgtatatg ctggtcttac aactactgga tatcctatct
    40021 tattggcaaa ctcaagacct gcttctaaat ttgtaactat atcactaact attactggtt
    40081 gatttatttc tttcattact tctctaaata aatctctatc ttcgcccttt tttatagatt
    40141 ctatagatgt tcctataact tttacattat atttatctaa tataccagca tcatgtaatt
    40201 ctacagctaa gtttaatcct gtctgaccac ccatacctgc aagtaaacta tctggttttt
    40261 ctttttctat tattttttct ataaattcta ttgttaatgg ttctatatat attttatctg
    40321 caatttcttt atcagtcatt atagtagctg ggttactatt tactaataca acttcaattc
    40381 cctcttcttt taatgcttgg caggcctgtg ttcctgaata gtcaaactct gcagcttgac
    40441 ctattattat tggccctgac cctaatacta aagttttctt tatactatct aatttaggca
    40501 taactctttc tccttatcta aacaattttc acagttctta tcttcatcat ctatacaatc
    40561 aactttaatt actttatttt atcttaaatt caaatttact catcaataca tctatttaat
    40621 acatctatgt taattaaacc aaactttttg atttaagtta ttcttgtttt ttagttagct
    40681 attctaatgt tatttatttt actaattcta aaaatttatc aaaaatatag tcattatctt
    40741 ttggtcctgg gcaagcttca ggatggtatt gaacactgta tacatctagt ttctcatgtc
    40801 tcattccttc aacagtatta tcatttaaat ttatatgtgt cactttcatt tgttcaggaa
    40861 cttctgaaac ataataacca tgattttgag aagttataaa tacttttcct tcttctaaat
    40921 ctttaactgg atgatttcca cctctatgcc caaatttaag tttagcagtt tttcctccaa
    40981 gagctaaagc taaaagttga tgtcctaagc atattccaac tataggtttt ttaccaataa
    41041 gagcttttat attttctata acatcttcta ggtcttctgg gtctccaggt ccatttgaca
    41101 agaatattaa gtcagggttt atactcaata catcttctgg agatgttgta gctggaaata
    41161 ttgttatatc acatccacga gctataaatg atcttaatat atttcttttt actccaaaat
    41221 ccataacagc cacttttgga ccatttccct ttatatgctc tacttctttt cttgtaacag
    41281 ttctaactgc ttctgtattt gaaaacttat ccaatttatg tttaacatct tctaatttac
    41341 tgtcttctaa tgtaattata cctttcatgg ttccattatt tctaagtatc ttagtcaaag
    41401 ctcttgtatc tattccttca agtccgataa ctttattttg ctttaaatat tggtctatat
    41461 caatttcaca tctaaaatta cttggagaat cacttttctc ccttactatg aatcccttta
    41521 cttgaacttt ttcagactct gctgatgata aatttatacc ataatttcct acaagaggat
    41581 aagtcatagt aactatttga ccatagtaag aagggtctgt taaaacttca ccatatccta
    41641 tcattgaagt attaaatact acttctccta cactttcttc taaatatcca aatgcctttc
    41701 ctataaaaac tgttccatct tctaatatta accttgcttt catactacag tacctcctat
    41761 aattctcttt agacaaacta aagaacatta actaaatata agcttttaaa tatctatatc
    41821 tatttttcac ttttacattc tagttttata cttatttaca tttatttttt atctttttct
    41881 attatactac aaatttctta aaaaaaagaa gttatctcaa aagtaaaaac tcctagaaaa
    41941 aataacctct tttttttatt taataattaa attcttaaac tatacaatca acttaatttc
    42001 tattcagcta tattgtaaac ttttaactca tctttattta aatgtttctt cttaacttct
    42061 actaaagctt ttagtgtatc caaagatgtc attatttcag tagaaaattc aatagctgtt
    42121 cttcttatct taaatccatc tcttgtagag tcatttcctt tagttggtgt atttattact
    42181 atatcaactt gtttatttct tatagcatct aatatgtttg gtctagattc ttctactcta
    42241 tttactatat cagcctctat tccattttct cttaagctat tagctgttcc ttctgtagca
    42301 acaaaagtat atcctaattc tttcatatct tttgctatct ctataaactc atctttatca
    42361 tgattattta cagtagcaag tactactcct ctttcatcag acatatgtct acctgctgcc
    42421 aagaaccctt tatataaggc ttcttctaaa ttttctccta cacctaggac ttctcctgta
    42481 gacttcattt caggtcctag acttacttca actttagata atttagacat tgagaatact
    42541 ggtactttta ctgatactaa ttttggctct ttgtaaactc ctgtaccata tcctaaatcc
    42601 tttaatttag ctcctaacat acacttagta gccaagtcaa ctattggtac tccacttact
    42661 ttacttatat acggaactgt tctactagct ctagggttaa cctcaattat atataattca
    42721 ttttgaaatt ctataaactg tatattaacc ataccaagca cattaaggtc taaagctatt
    42781 tttttagtgt attctactat cttttctttt atttcatcag atatattttg acttggatac
    42841 attgttgtac tatctccaga gtgaactcca gctctttcta aatgttccat tataccaggt
    42901 atcaatatat cttccttatc acatatagca tctacttcta tttctctacc agttagatat
    42961 ttatctataa gtactggatt tttatggtct ctatcaaatg catcttgtag gtattgagat
    43021 aatttttctt cgttataagt tatttccata ccttgaccac caagtacata agatggtcta
    43081 actaatactg gataacctaa ctcattagca acttcaatac cttcgttaag tgaccataca
    43141 ccctttcctt ttggtctatt tatatctagt ctctctagta aatcatcaaa tttttctcta
    43201 tcttctgctg catctatatc atcaaaatca gttcccagta taggtatatt tttttcatgt
    43261 aaaaatttag ccaattttat agctgtttgt ccaccaaact gtagtattac accttctggt
    43321 ttttcttttt ctattatact taaaacttct tcttctgtta atggttcaaa atacagctta
    43381 tctgatgtat caaagtctgt acttacagtt tcagggttat tgtttatgat tatagtttct
    43441 atgtccattt ttcttaaaga ttttacacag tgaactgaac aatagtcaaa ttctatacct
    43501 tgacctattc ttattggacc agaacctaat actatcacct ttttcttatc actaacaact
    43561 acctcatcat attgctcata agttgaataa tagtaaggag atatagcatc tatctcacct
    43621 gcacaagtat caaccatttt atatgctggt ttgatattgt atagacttct caattcatat
    43681 aatttttctg gacttatctt cattaggtca gatatacctt tatcagagaa tccctttttc
    43741 tttaattcaa gaagatagtc tttagttaaa tcttcaattt tcataacttt taatttttct
    43801 tcttgctcta ctatccattt aaatttattt ataaaccatt tatctatacc tgtaatttgt
    43861 tctatcattt ctactttata gcctcttctt atcatttcag ctaaatcaaa tagtctctca
    43921 tcatcaggta ctacaactct tttctttaat tcctcaatgc ttctctcctc agatggtgtg
    43981 tgaactaatg aatattttcc tgtttcaagt gatcttatcc ctttaagaat agcagcctca
    44041 aaattacttc ctatactcat aatttcacca gttgccatca tcttagttcc taattttcta
    44101 tttgcttttt taaatttatc aaaaggccat tttggtattt ttgccaccac ataatctata
    44161 gttggttcaa aacaagcata agttttttta gttactgcat tttctatctc atctaaagta
    44221 taacctaaag ctatttttga tgaaacttta gctattggat atcctgtagc ttttgatgct
    44281 aaagctgatg acctactaac tcttggattt atctctataa ctgcatattc aaaactatgt
    44341 ggattaagtg caaattgaac gttacaacca ccttgaactt ctactgcatt taatatatct
    44401 aaagatgctt ttttaagcat tgcacattct ttgttactta aagtttgagt tggagcaaca
    44461 actatactgt ctcctgtatg aactccgact gggtctatat tttccatgtt acatacaact
    44521 atacaatttc cctttgaatc tcttattacc tcatattcta tttctttcca accttttata
    44581 ctcttttcaa ttaatacttg tccaacagga cttaattgta gaccatgtga aagtatttct
    44641 cttaattctt cctcattatc agctataccc ccaccagttc cacctagtgt gtatgctggt
    44701 cttacaacta ctggataacc aattgtaagt gcataatcaa gacctgcttg taaatctgta
    44761 actatatcac taactattac aggctgattt atttctttca ttacttctct aaatatatct
    44821 ctatcttcac cttttttgat agattctact gaagtaccta ttatttttac tccatattta
    44881 tctagtatgc ctttttcata aagttcaact gctaggttta gccctgtttg tccacccata
    44941 cctgcaagta aactgtctgg tctttctttt tctattattt tttctataaa ttctattgtt
    45001 aatggttcta tatatatttt atctgccact tctttatcag tcattatagt ggctggatta
    45061 ctatttatta atacaacttc aatcccttcc tctttcaaag actggcaagc ttgtgttcct
    45121 gaatagtcaa actctgcagc ttgacctatt attattggtc ctgaccctaa tactaaagtt
    45181 ttctttatac tatctaattt aggcataaat ttttctcctt atctaaatgg tttttactat
    45241 ctgtaaataa tactaaatct atattaatgc taagaattta ttaaatatac aatctaaatc
    45301 ttcttttgtt gtgtattctg gaatgtactg aacactatat attggtaatt ccttatgtct
    45361 cattccttct atagtattgt catttaaatt tatgtgagtt acttctgtat tttctggcat
    45421 ttctgaaaca ttatatccat gattttgaga agttataaat acctttccag tttctaaaca
    45481 tttaactggg tgattacctc ctctatgtcc aaatacaagc tttgaagtct ttcctcctaa
    45541 tgccaatgct aaaatttgat gtcctaaacc tattcctgtc aatggctttt tgcctattaa
    45601 tttttttata ttttcaacta tatcatttat atcctctgga tttcctgggc cattagataa
    45661 taagattaag tcaggattta tatttaaaat ttcttctact gtagtcattg ctggtactat
    45721 agttatatca cagttacaag ccttaagaga ctctagtaca ctatttttaa caccaaagtc
    45781 tataactaca actttagctc cagtaccttt tatattttca atttcttttc ttgtaacatt
    45841 ttttactgaa tctttgttac aatgctcttc taatttagac tgaacatctt gtaatgatac
    45901 attttctaaa gttataattc ctctcttagt tccattgttt ctaataattt tagttaatgc
    45961 tcttgtatct attccttcaa gtcctattac cttattttgc tttagatatg tgtctatatc
    46021 catttcacat ctaaaattat ttgggttatc acttttttct cttacaataa gtccttttac
    46081 ttgcacctta tttgattcaa catcttctaa atttattcca tagtttccta taagtggata
    46141 agtcatagta actatttgtc cataataagt tgcatctgtc aatagttctc catacccagc
    46201 cattgaagta ttaaatacaa cttctccaat agcttccttt agatatccaa atgcttttcc
    46261 ttcaaatact gttccatctt ctaaaattaa tttccccttc atgtaagcta cctcccaaat
    46321 attttatcta agcattttct atttctctta caatattaat agctgattct cttggatttt
    46381 ctgcttttgt tataggtctt ccaacaacta aataatgagc accttttttt attgcatctg
    46441 atggagttac aactcttttt tggtctccaa cctctgctga tttaggtctt attcctgggc
    46501 aaactgttat aaaatcagtt ccacatgctt ctactatttt atctacttct tgcgctgaac
    46561 aaacaacccc atctattcct gattcttttg ccagtttagc tctctttata gctaactctt
    46621 ctgttgtcat attacatcct atgtcctgta aatcttggtt gcttaatgaa gttaaaactg
    46681 ttactccaac tactaatggc ttttctatat ttaatctttc tgcttcttcc ctagcaatta
    46741 gtgcacattg tctcattcct tccatatctg atacatgtat tgtcattaac caaacattat
    46801 ctctcactgc agctttcact gcacttttca tagtatttgg tatatcatgg aatttaaggt
    46861 ctaaaaatat ttttttacct ttttctttaa gataatctat tgttttacct tttgtggcaa
    46921 cgtattgctc tagccctacc ttaaatatgt ctacactatc ttctaatctg tctattagtt
    46981 ctttagcttt atcaaattcg tcagtatcaa ttgcaactat caatttttct ttaccattta
    47041 tcatttttac atctcctttt taataaagcc taaataatca taaaaaaatc ctcacaccaa
    47101 aagaggcata aggattttat ctatacataa ctctattcat tagctatgag atatctttcc
    47161 cagtctctct ggactagttt aaaagacttt attatattta aatttttatt ttatactcat
    47221 caaaaacctc tagaagattt actagaggtt atatactaac attatctata accctttagt
    47281 ctctctggac tactttaagg aatttagctg taatattttt ctttatttat ataactttat
    47341 gtatctatag gataatttaa agttttatct tttttataat taaaccacta attgcttttt
    47401 atgtcaataa gtctttgaat tattcttcat ctttatcaaa caattttttc tcaaaatatg
    47461 attctgcatt atatattgca gcaactggat tatgcccagt tactctatct ttgacaacta
    47521 aagttgttat aggagcttcc atatatttca tggctaaagt atcgtgacca acacataatc
    47581 caagaattac attaaggtca accttagctt catttaaaaa taaagcttgt cctattggat
    47641 tgcacattac ctcatctgaa cactttgata ttgtttgaga tgcttctagt ccaattgtac
    47701 tcttaggcat tgccccattt ttacatataa cagaaaatac ttcaaaccca tgatgttcaa
    47761 atattttttg cactgtttgc atttctcttt ttagtccaat acaaaatgct atgccaatct
    47821 ttttataacc acacttttta gcaaactcta taatctcttt tagtctagta tattgacaat
    47881 acccctctgc ttcaactaat ccagcattat aagctatttt tctattctct tcttcttcat
    47941 aaagttgctt tgctttttgt tgtagttcaa tttctctagt tggacatatc ttcattaatt
    48001 tatccatatt tccattagaa cagcctctaa gattacattt tccacactta tacatatcca
    48061 atatcccctt ccaaaatttt attcatcttg cgattcttct ttttctagag ttacattttc
    48121 ttcttgggtt tcttcttctg gtttcacatg ctcgactaca gttataaaat atgattttcc
    48181 tattttattc cttataggaa gtttttcata tgaaacatct attttatttt ttatacaagc
    48241 tatatcaaaa tgtcttaagg ctacacctaa gctaacctta ttcatatctt cacagtgttt
    48301 cttaggtctc ttttcaaata aatgaagacc tcgttcatcc ttatggaaat accacggttg
    48361 agaatttttt acagatggag ctcttcttgt caattctaag atatctttcc actttctatt
    48421 cctatttatc ttatttatca tatcttttac tggctttcta tcaggtctag catatctcgt
    48481 cctaaacaac tcttcatttt ttgctggata tccaaatgct attattatat aaggattttc
    48541 tattttgttt tcatcatctt cttctgtttt tattccagct agataatcta aatcatcttc
    48601 ctcatcttct tcaaaattct tattcccaat atctacaaat tccaagatat cttctctctt
    48661 taagtttcct tccaaccagc aagtagctat tcccaatgtt gtaaggcgca aaactacacc
    48721 ttctgtagca aatcctatat tctgtaaata gtcctcacct ttgtctgatg taactactat
    48781 ataatgaggt gcctttactt tacattcctt acccatcaaa aaatgtatta tatgacctct
    48841 atcaacaaca tgtgctttaa tatttaaatc ttcatttaag tattctaaat ttttacaact
    48901 tctttttatt tcttccatca atggcttttt tatcttctta ctggaaaaat ttcttacaga
    48961 ttttctataa aaaatggctt cataaagctc catttatgcc ctcctaactg aaatcttctg
    49021 acgtataaac tctataaatt tatataaata ctttatattt tttatagttt tatttccttt
    49081 ttcctcctgc cctattttga aattcataag aatatctact ctagtttaat atagcattca
    49141 aaaggcttaa attctacctt atcaatgtct atacattagc ataatttttt tatttgattt
    49201 tctatgctaa tttaaataac aacactagct attacctttt taattaagct ttgccagaaa
    49261 aatttttttt catttataaa tatctatctc attattatat tataagtttt tttcggtatt
    49321 cttgtatagc ttttcactaa aaaagtattt ttatttctac tttaatatta ttatcaacaa
    49381 aaaacatact gcttaaataa gtttgttatc ctcataattt gttttaatta aaatattttt
    49441 tttatttctc aatctataaa gtataaatat tttgaatatg acccaaaatc taagtaaagt
    49501 tataatattt tataagttgt tcaatattaa aaacataagt aatgttataa tactttataa
    49561 gttattcaat attaaaaata taggaggata aatatgaatt taaatagaaa tttagaaaaa
    49621 tacgctgaat tagcaataaa agttggagtt aacatacagc caggtcaaat tctacttata
    49681 aagtcaccaa tagaatgtgc tgattttgca agaaatgcac ttaaagaagc atataaatgt
    49741 ggtgctaaaa atgtttatat agagtggtct gatgaagaaa gtactcttat taaatactta
    49801 tatgctccag atgaagcatt tcatgagttc cccaaatgga cagcagaaca atatgtagat
    49861 atagcaaaag aaggtggggc atttttatca gtctatgccc aaaatccaga tttattaaaa
    49921 gatgttgacc ctgaaagagt tgcaaatttt cagaaggcat ctggaaaagc tttaaaagaa
    49981 tggcgttctt acactctaac tgataaatgt aaatggaata tagtctctgt gccaacaaaa
    50041 gattgggcaa aaaaagtgtt tccaaattta tcagaagata aagcaataga aaaactgtgg
    50101 gatgctatat ttaaatgttc aagagtagat ggtcaggacc ctataaaagc atgggaagaa
    50161 cataatgaaa atcttaaatc taaaatggac tttctaaata aaaataactt taaaacttta
    50221 aaatataaat cctcaaaaac tgatttgact ctagacttgc caaagggtca tgtttggcta
    50281 agtggagcat ccaaagaccc taatggaata agttttaatc cgaatattcc aactgaagag
    50341 atttttggaa tgccacataa gtttaaagta aatggaactg tttatagtac aaaacctctt
    50401 gtttatggtg gaaacataat tgacaatttc ttcttaacat ttaaagatgg taaaataata
    50461 gatttctctg ctgaaaaggg actagataca ctagaaaaac ttattgaaac ggatgaaggc
    50521 tctcattatt taggagaagt cgctcttgtt ccatacaact caccaatatc caatacggat
    50581 ataatttttt ataatactct atatgatgaa aatgcttctt gccactttgc aattggttct
    50641 gcttataaga cttgtctgga aggtggaaat aatttaaaag atgaagaatt ggatgaacat
    50701 ggtgtaaatg acagtttaac acatgtagat tttatgattg gttctgctga tatggatatt
    50761 attggtgaga cttatgatgg aaagcaaata cagattttta aaaatggtaa ttgggctttt
    50821 taacatatga ttttaactaa aaagggctga tggaagttat accagacttc ccagcccttt
    50881 ttaatgttga tgataaatat tttttatatt aattaatctc attattatag attaattcct
    50941 attgttttaa acataagtat ctaaaactta tatttatatt atatataaaa tatcctattt
    51001 agtaaaacct ttattttaat ttatatgcta aaaatttaac tttgctattt caacagcaga
    51061 ctttgcatcc tttgaataat aatcagcacc catttcttca gcgtattctt ctgtcaaaac
    51121 tgcacctcct acaaatacct ttgcatttat ctcattatct ctcagtgcct gaattgtatc
    51181 tttcatactt tgaacagtcg tagtcataag tgcacttaat cctactaatt ttatatttct
    51241 ctttttagca acttccacta cttcttcaat agggacatct ttacctaaat ctataacttc
    51301 atatccataa ttttctagca ttatttttac tatatttttc ccaatatcat ggatatcacc
    51361 ttttactgta gcaactatta tttttccttt ggatacatta ttgctacttt tacttaataa
    51421 agtttccttt attgtattta atgaaacttt taccgtttct gctgattgaa tcaattgtgg
    51481 taaaaatata tctccactat catatctttt tcctacttta tcaagagcag gaattaaaat
    51541 ctcatctaat atataatttt catccttctc ttttaaaaga ttcagtgtta cattttttgc
    51601 ttcatctttt aatcctcttt caactaaaat atccaagggc aaatctttat caatctttgt
    51661 agatgaatcc gatttttttg aattatttat attgctatat tgatttatat agtttataca
    51721 tcctttatct gtgttattta atattttaaa agaattgata gcttccatca tactatattc
    51781 atttggattt ataattgcta aatcaagccc tgcccctaaa gctaatgtta gaaaagaagc
    51841 attaagtgct ttcctatttg gaagaccaaa tgaaatattt gaaacaccta atatagtttt
    51901 tactcctagt gtctttacca ttgttatagc ttttatagtt tctattgctt cttcttgttg
    51961 tgctgaaaca gttaatgata aacagtctat aaatatatct tttggtttta tcccataaga
    52021 aactgctcta ttaactatcc tttttgctat ttcaaatctt tcttcagcct ttttaggtat
    52081 ccccttttca tcaagtgtaa gtccaaccac acatgaacca tactttttaa ctattggtaa
    52141 tatactttct aaagactcct ctttgccatt tacagagttt actattgttc taccattata
    52201 atatctaagt ccttgctcta aggcctctac attggaagaa tcaacttgta aaggtgtatc
    52261 tactactgct tgaatctctc ttattaattt tggcattagt tttttttcat caatctctgg
    52321 aagaccaaca tttactccaa gtatttgtgc tccagcattt acttgctcta aacctaaatt
    52381 tatagcataa tcaacatttt cattttttaa tgcttcttgt agagattttc tacctgtggg
    52441 attcaatctt tctccaacaa ctgtaggcga ttgtacttcc acaaattttg atggtgaaca
    52501 gactacacat ttatcaattt tctcgataca tccctttgta acagaattta tattctcaga
    52561 tatttctttt ataaaacttg gattcgtacc acaacatcca cctattatag tagcaccaac
    52621 ttcaacgaac tttttaaccc cttcaaaaaa ttcttttgca tcgacatcat atatagcctc
    52681 tccatcaact atatttggaa gacctgcatt tgcttgaacc ataacaggga ctgtagctct
    52741 tgatgctatt ttttcaacta ttggtaaaag ttgtttaggt cctaatgaac aattaactcc
    52801 tattgcatct acacctagac cttctatagt agccaccata cattctggca tacatccagt
    52861 aaaacttctt ccaccttcat caaatgtcat agtacagaaa ataggtaaat cagagttttc
    52921 ttttgctgct aatacagcta ctttagcttc atataaatcc atcatagtct ctattactat
    52981 tacatcaact ccagatttaa cgccttgtag tacttgtctt ttaaatattt catatgcttt
    53041 atcaaaactt aaagtaccca taggctctag catttctcct ataggaccaa tatctaaagc
    53101 tacatatctt ggtttagtat tatctacatt ttctatagct tttctagcca ccaaaacagc
    53161 attgtcaatc acttcttcta cagtatactt actatctaat tttagttcat tacatccaaa
    53221 agtatttgta agaattacat tcgaacctgc ctctaagtat gctgtatgta tttctataag
    53281 tttatctgga ttttgaagac caaatacttc tggattttca cctaacttta accctttttg
    53341 ttgaagcatt gttcccattg caccatcaaa tattaatata ttatttttca gatattgtct
    53401 tatttccaca agagttcgct ccctttctat atgtacagtt tctatagttt ttacaatttt
    53461 cacacgactt ttctttctta gatttattta ttcttgtatt agaaatacct ataatagcca
    53521 ctactgactt tctcggtatc ataattccat tagaagtaat tgttagacct atttgttttt
    53581 gagcattcaa aacgtttaat atatctatat ttttttctat tggtaaatct ccatatcctg
    53641 ggctatatcg catagttata aatttatctt gctttaaaaa aaccttttct aaattatttt
    53701 gaacaatgtc acacacttct tctattgctg ttgttccaca tgaatcaatt attagtcctt
    53761 ttgttaaatt tgaataagag tgtcgtctta tttctttttc tatatctatc cctatagtag
    53821 ctgccataat tacacactca ttacattctt ttaaaagttc atatacatat ttactctcta
    53881 atgttaaatt tgttccctct aattctacaa cattatcttt atttattcta ataggataaa
    53941 tcctagataa atatctagga tttattttat ttttagttat agctacacat tcatcaatag
    54001 tatatttaag gtctttatct atctcttgac ctctgtattg taaatatctt aaaacttcac
    54061 tttgatttat gcttatatct tctcttccaa ttaaattatt ctccatatat atttaaagaa
    54121 aatcctttat ctaaaacatc ttttgcatat tcctttgccc caaataaaga taagtctctg
    54181 tagtttccac attctatagc tgtagctgct ggcattttat ctgattcaag aacttttttt
    54241 aatgcttctt ctaaaccaat cttaactgtt ttggcatcta catctcccca tagtattaaa
    54301 taaaatcctg ttctacatcc cattggagat aagtctatta caccatctaa tgtatctctt
    54361 aaataagtag ctaaaagatg ctctaaaccg tgcatagcag cagttccaaa actttctaca
    54421 tttggctgta aaaatctcaa gtcaaattta gttactttat ctccctttac tccatcaagt
    54481 acactacact ttcttacaaa aggagctttt acttttgtat ggtctagctt aaaactttct
    54541 actttttcca ttatttaatc ctccattata ctttaaaatt tgttacatta attctaaaaa
    54601 aaactcttcc tatctattat tgataagaag agtatattat ttcaagtcat ctcatcgttg
    54661 ttagcaggac cacctgataa aaggttggta taggatcact gagctaactc tctcccctaa
    54721 ctcttgataa gtatcttatt aaactgactt aaattatata ttactttttt atttttgtaa
    54781 acactttatt gttataatat ttatatcaca taatcgtact tttattttat aactaagctg
    54841 attgtattat tggcagttgt acttcaaaca cagtttgata tttatcgctt gaaacagtaa
    54901 tttctccatc atgtaaattt acaatatttt ttgtaatcgc aagacccaat ccagaacctc
    54961 caacatttct atttctcgat ttttcaactc tataaaatct atcaaatata tttggtaaat
    55021 ctaacactgg aattggttcc ccataattta tcacttttac aaccgccata tcttcctttt
    55081 tctctgtgac tatatctaca taatgcccat cttttccata tttcacagca ttagttataa
    55141 gattttcaaa tgctcttacc aatttatttg gatcagcttt tacaattaat ttttcttcat
    55201 taaaattaat tctactaacc ataaattctt gtttaaaata aatttcaaat tgagatacta
    55261 cttgacttaa taactctact aaatttattt ctattttgtt taattttatt gtattatttt
    55321 gcattttagt caattcaaac aaatcattta taagaacatt taaatttttc gatttttcat
    55381 atgcaatatc aacatagtac atcatctgaa cttcatcttt atacttacct tcttctatca
    55441 ctcctaaata acccattatg gatgtcaaag gtgttcttaa gtcatgtgac acatttgtta
    55501 ttaaatctgt ttttgtctgc tgagcttgtc tctcttcaat agttatattt ctaagttgat
    55561 ggactatatt attgatttta tgtgctagtt catcaatatc atccttttct ttatccttta
    55621 atatatctaa atcatactca atatctatac ttttttctaa gttaccttca tccattaaat
    55681 ttacagcact tttaatgatt tctaattttt gattttttct attagtcttt cttataaaat
    55741 ctacaatttg cttatttctc ttgtacgata taatggaata aattgctaat gatgtgattg
    55801 taaataaaaa tggataaaat aaatcatacc ctataagact tctgaaatct cttgcttgat
    55861 atacaagttg attaactaca gacatatcac tattgacata taatgatttt attatataca
    55921 tacttgttaa aataagcatt gaagttaaag cacagcttat tataagatct aatatgggtc
    55981 gaaacatatg atttaataaa cttttatttt tcaattttat atcctactcc ccatacagta
    56041 tgaattattt tttctccatc tgtatatttt tcaattttat cccttattct gctcatatga
    56101 accattacag tattattaga ttggtaatat ttctctttcc ataccttttc aaatatttct
    56161 tctgtactat atactctgcc tttattattt gctagtaaat ataatatatc aaattctctt
    56221 gatgtcaaaa ttatttcatt tccagccact gttacactat gtttttcctt atctataatt
    56281 actactccaa cctttatgac atctttatct tcattattag caccactaaa ataatatgct
    56341 cttctaatca gcgacttcac tctcacagta agttcaagtg ggttaaatgg ttttgtcaaa
    56401 tagtcatctg caccagtcat tatcccttgt attttatcca tgtcttctga ttttgcactt
    56461 aacataagta ttggtatatt caaactttct ctaacttttc tacaaacttc tatcccatcc
    56521 attttaggca tcattatatc caatatcatt aaatgaatat tttccttttt taaaatatct
    56581 agagcctctt ttccatcttc agctttaatt acattatatc cactatttaa aagatatatc
    56641 tctataaggt ctcttatttc cttttcatca tccacaacaa gaactgtatt attcattttt
    56701 acacatccta acttaatctt tgtatatagc tttattcata taaaattata ctatatttta
    56761 gttagtgtaa tctataaatt tattaatttc taaatttcca atataataca aattatttac
    56821 acatttatat tatttatttt gtaaatattc ttctaaagtt aatccttttg aataaatttc
    56881 ctcagcagca tccttaccaa catatctaat atgccatggt tcatatgctg tacctgttat
    56941 atcttcttta ccttcaggat atcttattat aaatccaaac ttgtgagcat tttctgccaa
    57001 ccatttagct tcttttgtac ttccaacaaa ccatctttct ggatttgtta aatcaataca
    57061 aagtccagtt tggtgctcac tgtaaccagg ctttgctaca tatgcatctg ccttttctcg
    57121 cccctgagat tttacccttc ttgtataagt atccagttga gtatcataag atctgtatgc
    57181 tgaagaccct aaaaactgta ttccttctga attagcttgc ttaactaaat cttcaactgc
    57241 ctttgcaggt tctcctgcca tttgtttttc ttcctctgtt gcttcttcaa caaaaggtat
    57301 gtttacctta gtaatatttt caggagtata gtttttgcta attccatttg tcttgtttac
    57361 caataatata tttgatatac tatttgagtg atttttattt tgagaatttg cctcaacatc
    57421 ttgttctgaa tcatgttgag cagctactat tggatcttta tctttcttaa gtaatctatc
    57481 tttagatata aatacactta taaatactac taaaataatg gctcctatta atttaaattt
    57541 tttcataatt aaatcttctc ctttttgtta tgtttgctat aatgttaatt ttagagtata
    57601 agacttaagt attttataag taaatcttaa ataaatctta aatttaatat ttttaaagga
    57661 tggtgataaa atgtctatac aaaaacttct aagtaaagct cgtaaggcta tacaagattt
    57721 tgatatgata caagaaaatg ataaaattgc ggttggactt tctggtggaa aagatagttt
    57781 aactctactt catatactta aaagttatca aagattttct ccacaaaact ttgaattgat
    57841 agccataaca ttaaatactg gaggtgttga taattctcca ctagataaat tgtgtaaaga
    57901 aataaatgtt cctttttatg aatttcaaac tgacataaaa gaaattgtat ttgatataag
    57961 acaagaaaag aatccttgtg cattgtgtgc taatttaaga agaggtgctt tgaacgataa
    58021 tgctaaaaaa cttggatgta ataaagtagc tcttggtcat cataaagatg atgcaattga
    58081 gacattttta atgtctatgt tttatgaggg tagagtaaat tgtttttccc caaagacata
    58141 cctagacaga caggatttaa cagttataag acctatggtt tacatagaag agtatatgac
    58201 taagaaaatt tcaaaagatt ctaactatcc tattatcaca aatccctgcc ctgcaaatgg
    58261 tcatactagg agagagtaca taaaaaatct tattgctaat ttaaataaag agatgcctga
    58321 ttttaaaaga aatgtatttg gtgctttaaa taattctgag aaattgttta tatgggataa
    58381 agagaagata aaaaatttta aataataatt aaaattttta aataaaaaag caagattgta
    58441 ttaattgtaa ataatcttta tataatctac acaatcttac ttttttattt attatatgtt
    58501 attatcttta atctatattt taatagttct taatagtatt tattttgtct aatacattaa
    58561 ttataactta aatattttat atattaattt aatctattaa ttcattcaat ctactggttt
    58621 aatccatttt tacagtatat acatctacat attataaaaa gcaaaattat attttctaaa
    58681 tattttatgt tagattataa tattaaattc tattatctct ggtatattaa aaaatctaaa
    58741 tggtaacttt gtacttccaa gacccgaact cacatataaa tgatttccat ttatatcata
    58801 aaacccttta gtatatttcc ttccatatgg aggagtaact aatgctccct taataggtaa
    58861 tcttatttga ccaccatgac tatgcccaga tagaactaaa ttcattgtat ctttactaag
    58921 catatctact aaatctggtt catgtgctaa caataaatta aaattcttat tatctatttg
    58981 actctccaga tattttatat taggatttcc atttaatatt tcatcaacac ctaatatatt
    59041 aatatattta tcatctttta attttatttt tttattttca tttactaaaa gattgaagtt
    59101 ggaatttttc ataatctgcc tataatacct aggaagttta tacatataat catgattgcc
    59161 aaatactgaa aattttccca acctagcatt catacttgat aaaatagttg taatttcatc
    59221 tacacttgga tttttattgg agtaatcaat taaatcacca gtaaatacta ttatatctgg
    59281 attcaaagtg ttaatcttat tagctacttt tttgagattc ttagttgaat aaaaactacc
    59341 tatttgagta tctgaaattt gaactacttt tatcctttca gatttactct caattgtatc
    59401 actttttatc aatgttccat tttcacttat attatatttt ttcacaatta atagactcgg
    59461 ctctatcgca actgagtata taaaaatcaa aataaatatt aagataaaaa attttaaaaa
    59521 atacttaatt tttgagttca aaatatctac ctacttattt atttttttaa actatttgca
    59581 ttacagactc aactttgttc atttttctgt catgcatttt tggcttattt gctgaaaacc
    59641 atttatatgt tgctgtaaga ccttctttta gtaacacatt tggtatataa agcccatgtt
    59701 caataagctt atttatatca agattaaagt ctatatttct aaatgggaaa tacgttcttt
    59761 ctctaaactc tactttttcc atatctacat attttattat aggttctttg ccaataattt
    59821 ctccacatgt atatataagg tcatcccaag aaattaactg tggatttgtc acattatagg
    59881 cctctcttac atgaggattt ttcattatgc tttccaatac ctttaccaaa tccccaatat
    59941 atataaattg attactaact tgttttcctt ttggtactgg tatcttttca tttttttcta
    60001 ttttttcaaa gaaataatac tctctatata aattattatt ttcaccatat atataagttg
    60061 gtctaataat tatatatggt atagggctat ttataataaa atcttcagcc tcttttttat
    60121 ttaacccata ttttccccag ttttcatttt cacctttctc attttcttct tttatatttc
    60181 ttccactatc tttatatact gctcctgctg acaatactat atactttttt aagttatcca
    60241 tacttataaa atcaatcaga ttacttacat cttcttttgt atatgctgtc atatcatata
    60301 tgtaatcata ttttcttcct gtgataatgt tttccatatc ttttcgaact tttctatcac
    60361 aaattagatg ttctttaaaa ccattataat ctatttcctt tttaccattt gtaagtatat
    60421 caatttgata cccacattta atcaagcgct tagcaagtgc agaacctatg aagtcgcttc
    60481 cacccataat taaaatagat ttcattttaa gtgcatcctc ctctttttta aatgacttcc
    60541 ttaactataa tatcatattt ttaaatatgc gacaccattt tgtaatattt ttgtctataa
    60601 aagatattta taacaaaata tcttttatag actctacatt ttcgacaata taagtaggtt
    60661 cactttcact aagttcttca aaagaaccat acccatacaa cactccaata gaatctatac
    60721 ctattttttt ggctccaatt atgtcatact ttctatctcc aaccataata actttatctt
    60781 tatcttttac attacatagg tctagtacat attgtataac ttcattttta ttcactcttg
    60841 taccatcaag attgctacct gctatatatt taaaatatct atctatatca aaatatctaa
    60901 gtatagtttc tgcaaaaact gttggcttag aagttgctac taataatatt ttaccatttt
    60961 tatagagcat ttctaatatc tcttttatat tctcatagat tttattttca aatatccctt
    61021 tatcagcaaa atattctcta tacttttcaa cagcttcttt agttttttta tcttcaaatt
    61081 tataatactc cttaaaagta tcatgtaatg gtggtcctat aaattggtct aagttttcca
    61141 aatcttcttt tatgccaaag ctatttaaag aatactgaat agactttgtt attccttctt
    61201 tagggtctgt aagtgttcca tctaaatcga ataatactat ttcataattt tttttcatat
    61261 ttcagtcctc catatttgta aaaagtaata tcttatatat taagtttatc tattttaaaa
    61321 agctatagta atagaaattt ctaatactat agcttaagta cccaattaaa tcttatatat
    61381 ttattttaaa aataaattta aacagctcta tttaactgtt atagctgaaa ctggacatcc
    61441 ttcttcggct tctttacata aatcttgtaa gtctgctggt atttctcctt caattgctac
    61501 tgaatgccct tcatcgctca tactaaaaac gtctggacat gttcctatac atgctccaca
    61561 agctacacat acatccttat caacaaatgc tttcatacta aaatacctcc cctaaaatta
    61621 ttatttttta attgttgttt ccttagatat ttatccaata tataccaatt taaacatata
    61681 tttattattt tatcactatt gtttagttta ttatagtatt ttcgtatcca tgtctataaa
    61741 cttcactgct tttcatccat gattttacag tatattgcaa tcttaatttt ttatttaaaa
    61801 caagttcatt attattgtag tcttttataa tatcattaca ctcctccatt gtgaatattg
    61861 taaaatcacc ttctccacca atctttattc tgcctttatt tccatgtaaa tcgaaaatct
    61921 ttgttgggta ttcagttact ttttctatac acttttctaa ggatatccca agttccataa
    61981 ttttatttat aacacttaaa agagaatagt ttacgtcttt catgtttttt atatgcatat
    62041 cagtacttat taggtctggc tctaaacctt gctttattgc ttttttaaaa actttaaaat
    62101 caaattggtt caatccatga catacatcaa acaatactcc tctgttcttt gcatttatta
    62161 ctgattttct taatgtgcca gattctttaa ggattccatt tgtactattt ccatatactg
    62221 gtgtaaccac atctcctttt cccaaaatat tcattacttc atctatatat gatggatact
    62281 ctcctatata taccactaag ggtaaattta attttttggc aacttgcttt gatttcttaa
    62341 ttatatctat accactttca ttagattgaa atttactcgc ttttactttt atacccttta
    62401 tcttttctat atttttttct acaactgact caaccttgtc aaaatttata acatctaaag
    62461 aagttgattc attcaatata tttagtccct catttgtaac atttaaaaaa gaatatactt
    62521 ctgttttaca ctcatccata tacttttttt taaaatcata gtagtttaaa ggaccagctg
    62581 tacctgcatc aaatataact gtagaacctt tttcaattcc aattgaatca gaatccatac
    62641 ctgtaggtaa ttttctctta taacaatggg tgtgaacatc tataaatcct ggggaaatat
    62701 acatattatc ggcatttatt atctcgaact ctttatttgt aagtaatttt tcttttctta
    62761 ttttctcttt aaggttcaat ccaatagcat atattttccc atgtaaaacc aagatatctc
    62821 ttttttcaaa tttgatacca tctgttggag atattattgt cccatttctt ataagcaaat
    62881 ttttcattta ttccacatcc taattacaat ataatttctc taatagcttt tcttacataa
    62941 agaaaataag cctaaaaata aaaatatttt agacttattc actatattat actatattaa
    63001 ttatattaaa ttaaataaaa tctttaattt actttaagaa gcaattaagt atctgttgtt
    63061 cggcttcttc ttcagtaaga cctaatgtca tcatctttag tatttgatct cctgcaatct
    63121 ttccaatagc tgcttcatgt actaaaagag catctggatg atttgcagca atttcaggta
    63181 tagcactaat ttgagaattt cccataatta ttgaatcaca ttgaacatgt gcagaacaaa
    63241 gggaatcccc aataacacaa ggattaaact tttgcttaga attatcttgc ccaactgtac
    63301 gagaaactac ttgagcagaa gagttttccc cctctaagat aaccttcata ttagattctg
    63361 caacttgatt accatgagtt aataatttct caaatacaac tattttagct cctttaccta
    63421 ggtttgcatc catttctctt ttagttgaat ctacaccctt aatttgaatt gtttccattt
    63481 cacaatatga atcctcatcc atattgacaa tagtaactgg atttaaaatt ctctttcctt
    63541 ctccatcacc ttcaccataa tgtttttcta catattttag gcgagctcct ttacgtaaga
    63601 aaaatctatg tataccatta tgttcactat catcacaacc acagttatgt ataccacacc
    63661 cagcaattat aacaacatct gcattttctc caatttcaaa atcattatat accatatcct
    63721 gtacaccagt ctctgttact attactggta tatgtacatt ttctcctttt gtatttggct
    63781 ttactataat atctattcca ggtttatcag ttttaggaat tatagttaca ttttcagttg
    63841 aatgtctctc tactccttgc ccatttttac gtatattgta tgctcctaat ggagttccac
    63901 gaagttcagc aactttttct aaaagattta aatctatttt gttcatttaa tttgccttcc
    63961 tttctaatta attcatgtct ttcattaatt cacaacttga attaacttga cacatgattt
    64021 caggtaatat agcctctttt gttccatggc tttttactga accatcttgt agaacaatta
    64081 tttcatcagc taactctaat attctttctt ggtgagaaat tatgattata gtctggttag
    64141 actcttcatg tattttctta aaactttcat tgagtttccc aaagctccaa aggtctatcc
    64201 ctgcttcagg ttcatcaaat atagaaacct ttaaatctct agcaaaaaga gttgctatct
    64261 caattctttt catttcccct ccagaaagag agttatcaac ttcacgattt aaatagtctt
    64321 ttgaacacaa tccaacatct gtaagatatt ggcaacatac atcagtagac aatggttttc
    64381 catgagcaag tgtaagtaaa ttttcaactg tcataccttt tattcttggt ggttgttgaa
    64441 atgcatatcc tattcctttt tttgctcttt ctgtaatact aagatttgtt atatcttctc
    64501 catctaaaat tatctgacca ctcgtagctt tttcaattcc cataataagc ttagcaattg
    64561 tagattttcc tccaccattt ggccctgtga taacaataag ttttcccctc tcaaatgaaa
    64621 ggctaacatc atttattatt cctagttcct cattgttaga ctcaacatta aaggaaagat
    64681 tttttatttc aagcataata cccctctttt ctataaaata ttacattaat atccattctt
    64741 ttattatatc agtaattttt atatatcagc aactctaagc agataaaatg tatattaaat
    64801 aataaaacaa agttattgaa aagtaaaaaa gatgagtttt atgtaaactc atctcagaaa
    64861 tttagtatat caacttatat gtatttaaaa attagccttc tatatactct aatattattt
    64921 tttgattatc ttttaacata atttcttctt ttttagattc tattccattc ttttttatct
    64981 tcacctcagc tacaaaggca tcattacctt caaccatttc taatagttca taagcttttt
    65041 tacgacctat tttagttgct atatctttta gtactgccat tttcttaaac attttatcac
    65101 ctctactcaa aatttacact taatttttaa ttatataatt ctaatcctag actagtttat
    65161 aataattatt gtctctaatt atatcagata ttgagtaaat ttaatacttt gtaaaattat
    65221 ttatcctctc tgaccaaata atcatttcca tcttggtctt taaaagaaaa catccttcca
    65281 tatggcatct ccattaattc cccaacctca acctcgttat ttgccatttg ttcataagtt
    65341 ccattaatat ctcttgtact taaaattatt gatggatgag atacatttat ctctttgttt
    65401 tgtctcatca ttagattttt atcatacaac acaaatgttg taaattcatt tttacttggt
    65461 gctacttcca cccatttcat atttggaccc atttcctttt cataagttac tacaaagttc
    65521 aatttttctg tccaaaacaa ctttgcatcc tcttgattat ttacatagag agttattttt
    65581 cctattttat ttatcataac aatacccacc tttattatta aataaatacc taatattttt
    65641 tatatttaat aatataccca tatatattat tttctataga tatatatttc taatatttat
    65701 cgccaaatta tgtaattctg ctcaatatat aatttatagt atccatacta ttataggctt
    65761 tatttatgta atttaatcac cttatatatc atacttataa ttatgataat aactacataa
    65821 aaaatcactt ctaaatagag ttatccatct aaaagtgatt tcatatattc tatgcaactt
    65881 tgtgttttag ccactttgtt cctcttaatc ttaaacaata taaagtccct ctaacaagcc
    65941 aatcagtata catacctatc caaattccta acactccaaa ttctaataca acccccaata
    66001 cgtaacctgt aaaaattcta aaaatccaca tacctattac tgcagtcatc attgtatatc
    66061 tagtatcacc ggctcccttt agccctgctg ataatacaaa ggatataggc catattacca
    66121 tagctaaaca atcacttcga attaattgtg ttgagatgtc aattacacta gcattttgag
    66181 tatacatact tgaaatccaa ggtgcaattg gtataaatat agctcctact ataaataaac
    66241 aaattgttgc aaatttagtt aaatataata aagtactctt agctccttta atatctccac
    66301 gtcctatata ctgtcccacc aaggttgtag cagacaaagc taaagcattc ccaattacat
    66361 ttattatgga tgcaattgac attcctattg cattggatgc aattgctgat gttcccatag
    66421 taactataaa tacttgaaca atcaatttac ctgcattaaa aagtagttgt tcaactccag
    66481 ctggtattcc tatattaaat atagactttt gagtttcaac atcaatctta aatggaaata
    66541 ttttacccat agatataaat tcgtttcctt taaataaagc tcttataatt actatacatc
    66601 caattattct agctatagca atagatatag ctgcacctgt tatgccatag gatggtgttt
    66661 gcaaatttat tcctagagga tttaaatcaa taccatatat aagtatatat cctaatgtta
    66721 catttactat attcataaac atagtcacat acataggttt ctttacatct ccacaccctc
    66781 ttaaaagacc atttgctatt tgttgtgtcg caataaatgg atacgtaaat aatgtaaact
    66841 ctatgtataa ttttgcattt gattttacca attcttctgc ggaaccataa aataaattaa
    66901 ttacaccagt tctaaaaacc cacatcaata ttgttattgt aaaggataat attactccag
    66961 acactagagc ctgcttaata gtttcattca ccttttcacc atcttttttt cctatttgtt
    67021 gagctacaac aacagtagct ccaacagata gtgcagcaaa tacagatata aatatattgt
    67081 ttattgaatc aaccattcca actgcagata cagcttcttc cccaatatga cctgccatca
    67141 ttgtattaaa tactcctaaa agcatgacaa acgtctgctc tatcattata ggaattgcta
    67201 actttataac atttttcctt ataaacatcc ctattcctct tttccctctt tatataaatt
    67261 taatttttaa ttagtttatc gaactgtaaa ttgacaatgc aaagtttaga attgtattgt
    67321 tcgcattata atatactgct ttcaaataat ataaatcttg tttaatatca tttgaacaca
    67381 gtatatcttt ataattatct tatgtttatt attttttatg gataccacat ttaaaatatt
    67441 tattaattta atataaatat tttccgttat tattaaaagt agctatattt cgttaatatt
    67501 gtatcactat cgtgtagcaa taacaataag tacattttat atatttttta taatattatt
    67561 taatcatcca aacttttacc actttttcaa tatataaaat attacacttt agatgtaaca
    67621 aaatcgcatc catttaaata ttgtatttta tagactaatt ttaggatgtg atactttggt
    67681 taatttaaat gcaaataatc taaatgtaaa tatggtttat cctatttctt ccacagcacc
    67741 catacgtttc agaagatata ctgtttcata tttagaaaac atggaaaata tttatttaac
    67801 tatagcaaca tactttgata cacttggttt aggcacaatg aatatcgaca aagtttatgg
    67861 tcaatgggct tggtttactg ataatatata tgatttaaat ctatttgttt ttgtaggaaa
    67921 ttatccttat caaattgcta aaaacagata tgatacattt gtagatattt tgccagtagc
    67981 tattacttct attgtcaatg gagatagaat atttttaatt tcaaatcctt gtttgttaaa
    68041 ttcaaaaatt acagttagat ttatatctag tcatcctact cttaatagaa cagttgatta
    68101 tggcaatatt agagatttta ttttttaaaa ctgcaacatg atgtgctatt aaaaaatacc
    68161 ctaaatttaa tgatattatt aaataactag aatattttta attggcacat catgcctagc
    68221 tattataaat tcataatatt attttactta agataagtac tgtattttat ctacttgtat
    68281 atttttattt acctagtttc tcagttctat atcctatttc tttattagct agcttataac
    68341 cttcttgtat catttcttct ctcgttaatg cactccctaa taaattgtca atactcagtt
    68401 gctttctatc actaaaatac ttatccaata atgattcctc tatatcttcc tgatatgcca
    68461 aatttccttc atgcattata tattttacat caaaaccttc tttatttaat acttttccca
    68521 ccaagatact tctatgacat cttataggtt cttgcatagc tcctaataaa actatcctat
    68581 aacccatttg acaacccttt tttaatcttt ctattccgtt taaaaaaata tcttcttttg
    68641 ctactttctc aaaatctgca taaccttctt gcgtatatac atctttatta gttcttttag
    68701 ctccaaattc ttttcccatg tatatatata aaaatccgga atttctaaga gattcgttaa
    68761 atgcctcttt attgtattga atattatatt tagaatatgg agtttctcta atgtcaacta
    68821 cacaatttat gtcatatttt tttatcatat taataagctt atcatatgga taatttgaat
    68881 gtcctattgc gaatatttcc atataaacac cctcctattc tttgaaatta gtatctatat
    68941 atgtagatac ccgatttact taaaattaaa taaagtatta ctttaaatac ccaatatctt
    69001 tttttcttga tattgtatat ttttttactt tatatcctta aaaaaatata caactttata
    69061 tataaaacat caatatttat atatattttg tatattaaat acaattattt ataaagtctt
    69121 taataaaaat ttataaatag agcatcttta gaaaactatt ataataaaaa aataagaggc
    69181 tgtctaaaaa tatagataag ccttttttca taatcgtaat tataaaaata tacttgattt
    69241 catatgaaaa agagtgtctc ataaactaaa atgtttactt tgagacacca ccttttttat
    69301 tcttatttat actttgtaga catattataa catgcgtttc actggtatct gaacttctgt
    69361 caaccagtct tcttcactct ctttattcca tataccatct atataagatt ctctaggatt
    69421 tccaaccact ttatatttat tgtcctctat ccatttaaat gcatctgcgt aagtttttcc
    69481 taatgttgaa tatggaccat tgtgtaatat acaaactgca ttttcaactg catctaattc
    69541 tttaaatttt aatatatccg tatcttcctt taaatcattt atagcttgac acatttcaac
    69601 atccatatca gtctctctat attcaccatc atgatatata ttaaaacaat aatcaggaac
    69661 tgcacatgta caccctgttt tcatcatttc ttcagccatt acatttggaa atagattaaa
    69721 aagttcatca taccccttta acacttttct catagaagca actttaactt ttggtaaaga
    69781 cttaataatt acatcattca tattgacttc tcctttcaaa ttcataaggt aattacgtag
    69841 tttaattatt ttatattctt cacttttaat tacatccaac atttcttttt ctttattcat
    69901 taaaatattt tcaacttctt caggattttc tacagctttt tttatctcag ctaatgataa
    69961 acccatttgt tttaaagtta ttatctgatg taatttaggt aattgctctg ttgtataata
    70021 cctatatttt gtaaattcat ctacatattc tggttttaac aaccctatat cttcataata
    70081 ccttaatgtc tttgtagtta ttttatttat tttagaaaac attcctatag aaaacatctc
    70141 atcacctgcg cattagattt gattaattta agtttaaact ttccccttag gttaaagtca
    70201 atacaaaata aattataatt gtattaattc ttcaattcta tctccactca ataccaaaat
    70261 atcccctgtt tttataatgg ttgaaccttt aggtattaaa acctgttcct ttctttttat
    70321 cataactatt aatatatcgt ctggtatatt agaatctatt atactcttat tagcccattt
    70381 attaccctca tcaacattta cttcgataag tttagagcta atttctccat cataatcatt
    70441 aaatgttttt aatacaggtg tattatcatc aactaaatcc aactttctgg ctacagttgg
    70501 tatcaatgaa ccttgtattc ctactgaaag caacgctata aaaaatatta tatggaatat
    70561 gtcattctct atggctactc cttgagtaac agcataaatt gcaaaaacta ctgaagccgc
    70621 acctctaaga cctacccacg atatgaataa tttttcttta tttgagaatt taaattttgc
    70681 tagaactata aatgttgcta atggtcttgc aataactatc atgaatatag atatggccat
    70741 tgctatacca aatacatttg gtaacttaga agggaaagat aacaatccta acataaagaa
    70801 taacattatt tgcataatcc atgaaattcc atcaaagaaa tgaaccaaac tttttttaag
    70861 aggtatccta ctatttccta taataatacc tgaaatgtaa acacttaaat atccatttcc
    70921 tccaagatac tcgctaaatg cataagaaag tattgcaata gctgttataa atatagtata
    70981 aaatccttct atctcgaagt ttgaatgtct taaaatataa acagataatt ttgctagtat
    71041 aaatcctata gctaacccaa aagctatttg ttttattacc attggtgcaa taagttctac
    71101 cccagaatta ttcatcaatg tcaaaagaat tagtgtcaac atatacgcta ttgggtcatt
    71161 acttccactt tcaacttcta ataatgatgc aagtgaaccc tttaagttta gtttttgaga
    71221 acgcaacaca gcaaacacag atgcagcatc tgttgaagct gcaattgccc caattaataa
    71281 accttcaagt aaactagttc ctattaccat gtggcaaaac atacctgtaa ccccagccgt
    71341 aattattaca cccagtgaag acattaatat agaaggtata gcaacaggtt tagccatatt
    71401 ccagtttgtt ccaaaccctc caaaaaacat tataaatatt agtccaatag aacataattg
    71461 ttttgtcagt tcatagttat caaaatagat tcctaccatc ccatcagacc caaataacat
    71521 ccctagtaag ataaaaatca ataatattgg tactccaaat ttatacaata ccttgctaga
    71581 agttatacaa atcaatagta ctaacccact tataatcatt aattctgtca tagcatcaac
    71641 tccatttcat ataaattttg tagattaatt tacatctaca attttattac ttattcaaat
    71701 ataacatgac ataaatttta taagttatgg tacataaagt tcaacaaaaa tttcacaata
    71761 cattaaaatg tgagtgttat acttaaattt atatatttgt tttaattata ttcatttaat
    71821 atttataatt tgaatttttt tttattaata tttcattttt tagttgattg tttaatatat
    71881 ttcatttttt atagtaattt tatatataac tacgaaatat aaagtaatta gataagtaac
    71941 aagaaactaa catgtaatgt taggtactct agatatgaaa tcttaaaact tttaaatatt
    72001 gaaatatttc tttatatata ttattgtata tttcttataa attattgtca atttattttt
    72061 tcttaaaaat aaaataattg cataatttat ttcaaattat gcaatttata aaatttattc
    72121 ccaaaactct tttactgctt cgattatctc actataaggc aataaagtcg cttcgattat
    72181 tgatttattt gtcttttcta aataatactt aatcatataa tatccacaag catatcctgc
    72241 acaataaggc aaccctactg gaaaatatcc ttgcatttta gctatatcat caccataaag
    72301 ataagatgtt atattttgaa atccagtttc ttttaaagca ctttttatta ttggctttat
    72361 ataagtattt aatgtttcga tatctgttct actgacccaa ggtcctaaca tttcctctcc
    72421 aaacatccat gttgcaaaat tttctgcaag accttcattt atcatcattt cttctaatgt
    72481 tatattatta ttccactcta taaactgaaa tctaatattg tgattacatt catgtgctat
    72541 taatactggt aatctattga tagtatattc attaggaacc aatgatagaa atatatatcc
    72601 aggaatccca ccatcacccc agtatccatc acttaatatt gtataaggac tatttggatt
    72661 cgccaataat attgaatatt tatagtcctt aatatttaaa tcataccctt cttttataaa
    72721 agcatttata gagttttcta tggtttcttt acaagtggcc caaattttat cagcagataa
    72781 cacatttata ttcttttttt gtttttcatc aatatcctta ggcgataaaa cccctaacat
    72841 ttcacttgct ataattacat catatccacc tttctgtcta gcaactattg gaacattcat
    72901 acacttccac ttaaattcaa aaggcttcat caattcatat ctgtatatat cttctttttt
    72961 gtttattggt gcatccatta tcttcttgta tattttatct gagcgaattt ctataatatt
    73021 catatttacc atctccttta agacaaagta tatacaatta cgtagcgtca atgtcaatat
    73081 acatttttta taatgtcacc ttaatctttt tattatattt tatcctgtaa accttccgta
    73141 catataacat ttttttaaat taataaattt gtataatata ataataaaaa attatatact
    73201 tcaaggtttc cctatgatac aatttactaa atcataattt agattatcag gtgcaactat
    73261 aaattattct atatcaagga ggatatattg gtcatgctaa ctccatattt aatatttaat
    73321 ggtacttgtg aaaaagcatt taatttttat gctgaggctt tcggaggagg aaaaactata
    73381 tttgcgcgat tagacagcaa tccaaacaat cctattatgc acgcaagtgt tactttcaca
    73441 aaatacgaag gttgtataat gggtgcggat acagacaagc ctgttgtaat ttctggcatg
    73501 gcgatttgtg ttgttctacc atctcgagaa gcgatagaag aaatatctgt aaaacttgcc
    73561 gaaggtggta cacttgtaca agaattttta ccacacccac caccacatca aaatgatggc
    73621 gctgctgaag tacttgatag gtatgggtat acttggtatt taagtacata gttaaaataa
    73681 aaaaacgaca tctaataatc ataatataga acagataaat ttcaatttaa tagtgtagta
    73741 aaaaagtcgt gtcctaagac tgtcacgact tttatttgta taaaaattta agtaaatatt
    73801 tttgcgaata aatgagaagt ataactttaa attaatttca tatgtagtat tggaaatggg
    73861 ttaccttgtc catctatttc agacctatca aacactttaa atcctaagtg aatataaaat
    73921 cctacagctt ttttattctg ctcatttaca tcaacatatt ttacattgta tttatctata
    73981 gcatatttta ttaatttttt accaatacca tttcctctat atttatcttc tataaagagc
    74041 atctcaattt tatctttatc tattcctata aagcccttta ttatatcatt atcttttata
    74101 caaactatat tttctacttc tttaagtcca atctcaacta atggtatcaa agattcaata
    74161 tctttttctg ttaaaaaatc atgcgttgct cttactgatg attcccagac ttgcaacatt
    74221 tcgtcatatt ctgttgaatt tatttgtttc atttcaagaa ttattccaga tttcataaaa
    74281 atttcctccc tatatcactt ttaattgcat aacacttttt tatacaaaac ttagaaagga
    74341 ctacgaaggt taaatatcat agtcctcatt aagtttaaat attatctatt atatattatt
    74401 atactataat ctagcaaatt cactacaata attcacatca gcttatacta aaggtgcttc
    74461 tatttgagta gtaaaaagga atttatgaca atgaccatca ttaacagtag tttctccaca
    74521 tattaagtga atgtgtttat cagttccagg tattctaatt gctggccctg ttgtaacaca
    74581 tatcttatgg aaatggtcaa ggaaatctac attatcattt attttatgaa catgatttgt
    74641 acctccattt attggtatag cttcaccagt aacccctgct gcacggtggt tatgtctatc
    74701 ctcacattct tctgctaact taacactttc tgaatattca tgaacatgtg tcatttcctc
    74761 ataatcatta tagcacttgt tgcacttatt gtatttataa tcatcataca cataatctct
    74821 ttcacattta taattttgat aactcatttt tatatctctc cctatattat attaagaaat
    74881 tcttgtaaag aatctctaat gtataatatg aattaaagtc aaaaaagttc atgttttgta
    74941 aaattatgta ttaatttaat tatttttccc agtatttagg gcgtattagt gaagctggta
    75001 acttcgtact agaatctcct tttgcagtat ttacttgtaa ttgtgttaaa aatatactat
    75061 tttcaagatt agcacctcta atatcacaat ctcttaagtc tgctcctatt aaatttgccc
    75121 cactcaaatc tgtatttctt aaatttgctg ctattagaaa tctacctctt aaatctgctc
    75181 ctattagatt tatttttcta aggtctgctc ctattaaatc tatattttta cttaattttt
    75241 tcatgttttt aagagtagaa gtcttgataa atgatttaac ctttcccatc acagactcac
    75301 tcgcttgtga taataataaa ttaaccttta ttctatgtga tatgatatcc aaattaatta
    75361 tctgttctgg gctcatatta gttatctttt cagtttcttc aattattaaa tcaatttttg
    75421 atttgattgt atctgatata tttaatacag atgcttcttt aagataccat aacatttcat
    75481 gtaattgtct cataattaaa aacacttcag acatttgatt tgttagttct gatgattgca
    75541 tccagtctat ccccttatat gttacttgtg ctactttttg acctgaacca aaacaatcat
    75601 atgcagtaca ccctttaaaa cctcgcttca taagactatt atgtacagaa catttaaaat
    75661 ctggttgtaa attaatacag ggttttcctg attccttatc gataggaaat ccatctgaag
    75721 cagaaaaata aagagctaca cagcaaagtc caaagcactt cttacagtca atctttagct
    75781 cctcaaataa cttattatca tatatatttt tatgtatatc tatcatattt tttctcctct
    75841 taaactttat ttttaatatt atattatcta taactaaatg ataatcaagt cccttattta
    75901 acagttctta ttctttatta taatttaagg tattatttat tccaatagca tacataagtt
    75961 tctttatact tgtaacaata cctttatact aagacttatt ttaaatgtag cactgtaata
    76021 ataaattgtt tatatactca taatgtattt gataaattgt aaatctttat agaagttgaa
    76081 atttttaatg attttagaat caagatataa taataaatac aatttataaa atcagaaata
    76141 tataaattaa ctatacaaac ctaaataaca tagcatttaa atttacaatt tcagtataaa
    76201 tagtacaaag tatattaatt taaataagat tggcttattt gtagaggaga gaatattttg
    76261 gtgttcaata aaatttatat ttaataaaac cataagaaaa tataaagata aataaacaaa
    76321 cttttattac ttaatagatt cttatggttt tatactgtac tgaaaaacaa taaacactac
    76381 agcttattta taatattacg cttttttaac aacagaagac tttagcttca tagctccaaa
    76441 accatctatc ttacattcta tatcatgtcc atctgatgag tcatggatta aacggatatt
    76501 tttcactttt gttccaatct ttatagatga tgaacttcct tttactttaa ggtctctaat
    76561 tactgtaaca gaatctccat catttaatac atttccattt acatctttga taatatttga
    76621 atcttcttca gctcccaatc ctaatgccca ctcatgagag cattctggac aaactaaaag
    76681 agttccatct tcataagtat attctgaatt acatttcggg caatttggta aattttccat
    76741 ctttatatgt cctccatttg ttatttttag atttcttatt atataaaatt tcttttgagc
    76801 ctttatgata tcatattata cttatattta caaactacta atttacttaa tgtttaaatt
    76861 ctattcgtat tattattaaa cttgatttag ctgtaatctc tttcttatat ttattatagt
    76921 tgatattatt acaattttat aactctatct gcctgctccg ataactctaa atcatgagtt
    76981 acaaatacga tagttttacc attcttattt agacttttaa gtatatcaaa tactatgtct
    77041 ctattttttt tatctaaatt acctgtaggt tcatctgcaa atattacttc acattctttt
    77101 aatattactc ttgctaatgc taccctttgt tgttctcctc cactcaattc gtatatcttt
    77161 tttttattgt attttctaag acctacagac tcaagtgcgt aatttatttt tttattatgg
    77221 ttgatatttt tttgatactt taaagcaatt ttcaagttat tttcaacatt ttcattctca
    77281 attaaagcat aattttgaaa tagatagcca taaaaatccc tttgtaaaat tcttatctgt
    77341 ttactatttg gattttttat attatttatt ataatatcac cagaattagg tttttctaat
    77401 aatcccatta tattaagtaa agttgtctta cctgaaccac tatttcctgt tatcgctaca
    77461 aactcgccct tagaaatttc taggttaaat ttgtctatta tagatttatc tttaaatttt
    77521 ttagatatat ttattaatga aatcatcttt ttaatgttct ccttttataa ttttattaaa
    77581 tgaactattt gagataatct tgtctaatac aatagataca attacttcta taactaatat
    77641 tagaagtcca aataagataa tattattact taaatctact cttgttgata taatgcctat
    77701 tggaataatg tttgttaata ttaatgagac tattaacaac atacttctag ctgtagttga
    77761 ataaccaaat atttttttaa tatataactt atatttattt ctttcatagt agctagctac
    77821 tatattgtag gtaatcatta agtttgatat tgctattatt attatagtaa aaatttcact
    77881 attcaaatat ttttctagtt tatttatttc taaaccatac tcattataaa cagcatgtaa
    77941 actttggata tgcgcttcta caccttgagc ttcaataatg ctacttatat ctgcaagggc
    78001 atctaatttc ttagaattaa aatatacaca tctagatata taagaaagat aaaaagaatc
    78061 atcaatatta tctatgtcaa ctattgctat tgggtcatca atgagattcc tattgtcatc
    78121 cataacaagg gagttataag taaaatagct ttgattatta tctacatata ttatattaac
    78181 atttaaatct gacttctttg ttttgtttaa cgctctattt aactctttat tgtacatatt
    78241 ttctacttct attttttcaa aataaaataa ttctctaaac tcttttttaa tctcattttc
    78301 atgtacttgt aactttttag gaactaataa atttatagtc ttatcgtcat aatcgattag
    78361 attaaatatt tctttgccat ttgagtaaat agggttaact ttaagatagt ttttatttat
    78421 ttttatattt ttaccatatt gacttacttc tgggttttta ccctttgaat ttatttcata
    78481 catgtaactt ccatcttcaa gtttttcaaa attagttgaa tctattaaga aagcatcttt
    78541 ttcttctacc aaatttttat agaaaccttt aatcttggca tttttaatta cttcttcctt
    78601 tcctaaagat tgttcgcctg tatctttaag agtaagatta taaacatttt ttgctttatc
    78661 ccactcagat agatttccta actgagtttg tagcatatta taatttaaaa tacagttatt
    78721 tatggataat ataagaaatg atacaaatac aattttcaat gtgaaatgca ttatatttac
    78781 aaaaccataa gatttttttc catttagaga tagcacatat ttagaacttc tactattaaa
    78841 accaactatt aatatagata tcaaaatatt tatcaaaata catataatcg aaaacatagc
    78901 aaagtataag catgctctaa cacctatatt taattttaaa atatagatta tatatattaa
    78961 taatgctgtg acagatgata aaatcataat tctaagtata ttttttataa ctctagcaat
    79021 tatatctagc ttagagtatc catttaatct taaaatagaa gcctctctac tcacactaat
    79081 tgaataatgt attattgtag ccaagaaaca aaggataatt agtattaaat ctctaattat
    79141 tgaaggattt aagtataaat ttgagttaac atatctatca tgtaatcttg ctacaaaaat
    79201 acttctgtct acatttagtt ctcttaatat tttatttatt gtatcttcat tttgagttga
    79261 aatatataag attcctgatt ctccaacttc acttatttta ccaaaatccc taattaaaat
    79321 tgatatgtct ttactcatag ttgagaattt acctacttga ttactattat tagtgtttat
    79381 attactaata aattcatttg aattagtatt aggaaatttt cctgatttta actttatatt
    79441 gttattcaaa cttgtatcag tcgtatatat agataatttt tcattattat taaaaacata
    79501 ctttgatata gtcacattat tttcatctgc aatatcttta atccacttac tataattttt
    79561 atttaacttt ttataatctt taaacattac agatatactt gttgtctcgt tatataaaat
    79621 attattaatt tcattatctt taactatatt tagacctaat aaagatacta ttaatagttc
    79681 aattgtaaat aatacatata ttatcttttt caattatagc tccctcctaa ttgtttttat
    79741 tctaaaagca aaatacattt tactttagtt aaagtataat gctttgtgcc ttttctaaac
    79801 aactactata ttgtcacatt ctaaatggca agtgtctatt tcgtcacaaa gataaaaata
    79861 gccttaaagc agttaatttt ttataatcaa ctgttttaag gctatttttt atttttagca
    79921 aacaatattt taatagtggt ataaaattag tataattcat taatatagat tctagtcttt
    79981 tcagtaagca actaaaataa tatcttattt aaaacgaaat ttaatttaag tccaatataa
    80041 actttacttt accattaaat cgtgctagta cataggtatg cttctttttt attccatata
    80101 atggatatct tatgaatatc tatagaatca agataataag gttgtccaat ttggaattta
    80161 gaatatgtat ttttaaattt tttatttaca tataataaaa aattattttc tttattaatc
    80221 acacaaatac actggtcaat attatctaaa atattctggt attgttgaat ctgttgatta
    80281 agtttattat tttttttacg ttgtaaaaac attgatataa tttgagaaat caatgataat
    80341 gtacttattt cctcttgtga ccatagacgt agtcctgtgc attcatcaaa tccaacaaat
    80401 ccactgaaaa ctctatcttc tttatatgca cattgaagtg tagagtggat accttgacta
    80461 gaaaacaatt cttctagttt aggacttaat gtatggatat ctcgacaata aaaaactaat
    80521 tcatcctcaa aaagcttttc ataatcctca tagtcttgat aattgctgtt ttgcaaataa
    80581 gccatttgag aagagattcc ttcattacac cattcataag tattagaagt atatctacca
    80641 tcttctgtat tttcaaaaat ataaacacga cttacatcaa actgtttccc aacaacctca
    80701 agtatcatat taatcgcctg gtctatatca tcagtctgat aaagcatacg gaatatataa
    80761 cgtgtaagat tatcaggata ttcagcgtat tgtttttctg aatcaataac tgtaccaaga
    80821 gaagaacaat caaattcttc taattcttta aaataatctt ggttgtagat tacataatta
    80881 ttttttccca tattttttgc ttgatacagg gctttatcag ctcttgcata tatttccttg
    80941 aatgtagtac catcctttgg atatatagct attcctatgc tacaagttac ttttagaaaa
    81001 cttttttctt tctgaaatag atgacggaac atatacaata gttcttctgc tttcttttct
    81061 gcatctttaa ctgaggaaat attcttcata aaaattgtaa actcatctcc acctattctt
    81121 ccaacaacat cactgtcacg cattattttt ttcatacctg atgccatctc agtaagtact
    81181 atatctccaa tcatatgccc ttctgtatca ttaatctgtt taaaattatc tgtatcaatc
    81241 ataaacagtg cacccataac atttaaattt ttttcaaaat atttcttaat ctgcctttca
    81301 gtctcagcac gattataaat tcctgttaat gcatctttct ctgatatatg ctgtaatttc
    81361 tcaatctgtt ttctttcctt tgttatgtca atacctatac tataaaaaga tggtattcca
    81421 tcccaactgt cttccccact gatataacac aatgtaacag tccatatacg ttcttccctt
    81481 gaacgtgtat atatttttgc ttcaaataca acattatccc cagactcctt caaatcttgt
    81541 gccagtttct tactacgttt ataatcttca gaaaataaat atccacattg attattaagt
    81601 tcctctgcaa actgttcctt tgtatattca atcatattca aaaatatatc attacaccaa
    81661 agtatagtaa gataatctct tgcatctaat ctaaccattc ctgctggaat agttttcaaa
    81721 attgattctc tttcctgatc tttttttgct aatttatatt cagcactata catatcataa
    81781 gataattcaa tacgaactct tcgcccttgc caattcaaca tacggtcttt aattataaat
    81841 gttcgtttca gttttttatt ataaaattcc cattcatata tgtcatcttt ttttaaatac
    81901 gaatttgtac aaaacggaca tggcgaagtt ctaccttgaa ttacctcata acattttctt
    81961 ccaataagtt catttgctga tgcctgtaaa gtattgcatg agtgcttatt taagtatagt
    82021 aattcatatg tatccatatc gctaatataa acattcccag catactctga catcatccat
    82081 ttaaaattct ctgtactctc tttttccata tcagatagtt cttcttgctt tatttttaac
    82141 tcattaattt ttgaatacaa tatatagacc attgatttct cattatcttg tgattcaatt
    82201 aatataccag tcattattac ccaaacaggg tctccattat ttgctgaaat gcaaatttga
    82261 tattctatac tcttttcgcc atgatgataa gcctctaaaa aatgattttt catagattca
    82321 aaatgataaa gattctgttc ataataatct tttaaactag aaaatttaac taaaaattct
    82381 tcttctgtat atcctaataa ttgatagaat gatgtatttc cccatattat tgtaaatgaa
    82441 tcatctaaaa aatgtttact gaccccaata ctcatagatt ttagaatatc ctctgatata
    82501 acttcattct ttgttgcttg ttctttttta cacattcgat gtaacctaat gtcttctttc
    82561 attgttttaa ttatcctcct atctttagac tcacttttaa ttcactctgc tttttaatat
    82621 aatgataaaa gtgaatcttc aacgtgtata aattgatttc atttacaatt attttttgtt
    82681 tgaaattgaa ttttcacaca cacttgctaa gattctccct ctaaaacttt taatttagta
    82741 atttttttga tgccctattc accatttaat atcttaatta tcgattcttg ttcacttaaa
    82801 tctgtattta acttttcccc taaaaacaca ttattttctc atatttacta aaaatcgcct
    82861 tcttttaatg aaattatatc ataacttaag ttttaaatca tttttttcca gatagaaaaa
    82921 ttaagataaa attactgaaa ttatatgtaa tataatagaa atgtaaactg tttttaattt
    82981 gaataatatt aaaaaggctg tatcatagta attataagat actatgatac agccctatgt
    83041 taaatttttc ttatattttt aatgatttca cgaatctttt tagcattttt agcaatatct
    83101 tcaacagaac ctttagttaa taaaccacca aatccacata catcaactcc attttctaac
    83161 catatatgta ggttttcaat attaatccct ccacttgcta aaactggcat atcaggtatt
    83221 ggtgtcttaa atacctttac tagtttaggt ccatagaaat ctgatattgg gaaagctttt
    83281 ataaaagttg ctcctaaact tagtgcgtct actgcctcag tcaatgatgt acatcctgga
    83341 gcataaggaa tctgatatct attgcaaatc ttcgctacac cttcattgta atttggtgca
    83401 ataataaatt gagctccatg taatatagca tgacgagctg tttcactatc caaaactgtt
    83461 cctgctccca cacaaagtgt ttcaccatac tttttattaa gcccttgaat tatttctcca
    83521 gcattattta gggtataact catttctata actgttatac caccttttat acatccttca
    83581 gcaatttcac atgcacggtt aagattttct tctcttacaa ttgcaagagc cccacattct
    83641 gacattcttt tggttatatt catctttttc atattatcac ctctatactc atcaaaccac
    83701 tttacttatt cattaatttt agtcatgttt tataatatat atattaatta tataccagtg
    83761 taatttccct atttatatta tctattctca ctacttttat taagtattgt cctataattt
    83821 tcaactactc gtttaatttc ttcaagtact tccccagttg gttcagttac aggaagtcgt
    83881 gcagttccaa cattaattcc attcaagaca atagttttct tcataacaga tggaattgtt
    83941 ccaagtttca gtatacgtcg aagttcttct atactacttt gagctttttg agcttcttcc
    84001 aaatcccctt tcataaagtt ttcatagata gagataccaa tctctgtgag gaagtttgtt
    84061 gttgctgcaa cagctccttg actaccagct tttagactat ccagaataag tgaatctgag
    84121 cctgaaaaca cactaaaatt ctcattcttc gttgcttcaa tataagcttt catgttgtca
    84181 agtttaccac tactatcctt aattccaaca atattcttta tctttgataa ttcacgtact
    84241 gactctggtt caatattaat tccagtctta cttggcatat tatacattat aataggtaaa
    84301 ttaactgaat tagcaatagt tttgtaatgt aagattaatt cctgttgtgt tggtgtaaca
    84361 aagtatggtg taataataga taatgcactt gctccaatcg cttccattct cttagataaa
    84421 tctacaactt cacgagttga attaccccct gttccaacaa aaacaggtac acgattattt
    84481 gtatgattaa taacaatctt tgcaaattca actttttcat catctgttaa tacatgacat
    84541 tcaccattag tgcccaaaat aaataatcca taaattccct tttcaatcaa ataatcaatt
    84601 aattgacatg ttgcttgtga attaatattt tgattttcat caaatggtgt tatcattgca
    84661 catataatcc ctttatattt cataaaatta tattccctct ctaatagact ttccaagact
    84721 tcctgctgga tgccacttca aatactgctg tgtattaaga cctttagcat attgtaatac
    84781 aacacttaat gattgtaata ttattgtttc agctaaaatt gaagcacgag gagctttatt
    84841 aagacaatct ccttcctgtt taacacctgc aaacaggaat atatcagaaa tattttttaa
    84901 aaatgaactc tcattaccac ttacaccaat tatctttgct ccatttactt ttagagtctt
    84961 aagagttgct tttaactctt gagtttcacc actatttgat attgcaataa caacatctcc
    85021 ttcaactact tgaccacttg acccatgtac tgcttctgta ccatgcaata tatatgctga
    85081 cgttccagta gatgaaagca atgatgaaat atatcccgat acatgtcctg gtttgccaat
    85141 accagtcaca tgtacacgtc cgtgattttt ttcagcttca agaattaatt cgcatgcttt
    85201 atttatagat gtctcatcta ttgaggcaat aaattctgac aattcattag atatattatc
    85261 taaaaattca gataatgtat tttccataag atgtatcctc cttgaaatca tagtaactat
    85321 gactatactt ttatataatt tagtttaaat aggttttata aattgtaaaa tattatgtaa
    85381 tatcgaacca actacattgt aatcaatatt agggaaagtt gctccttcta taccaagagt
    85441 gccataaact ggatatagta taactggtaa aaatgcaagt aataacccca caacaaatga
    85501 cccagcaata gcccctctcc atcctcctga agtattgcca aatattgcag ctgtacctcc
    85561 tgagaagaaa catatgtgag cagctggaat aattactaca ggaaatatac taggaaatga
    85621 tgccataata gcaattgcta atagaccagc agcatatgct gatataaacc caataataac
    85681 tgcatttggt gcatatggaa atactgttgg aacatctagc gcaggacgtg aacctggaat
    85741 atacttttct gaaatgatta caaatgctgc agttatttca gctaagaaca tacgaacacc
    85801 tgacatcaat attgacatac ctgccacaaa tgtaaatgcc tctataagcg gaaaaaccaa
    85861 ccaatgtgtt gaaccagcaa tttcttgagt aaatgcttga ccagctttta atgttgcaat
    85921 ataaaataag attaacataa ctatggatag acccattaag aagtctctga atattgataa
    85981 ccacttagga aattctatag tctctgttgt atcatcttta tgttttgaaa ataaacgccc
    86041 aatataacct gataaaccat aaccaatcat gttaaagtga ccaatagctt gttcgtcgcc
    86101 acctgttaat tcacgcataa atggttgaca gaattgaggt agtgcagcag acataaaccc
    86161 taagatagtt ccacctatta aaatagtgat tgtattatca aatccatgtg ctttcataat
    86221 taaaactaat acacaagaaa agaacaaact atgacctgtt gtaaagaaaa tattcttaaa
    86281 ctttgtaata cgtgcaaata ctaaatttaa tatgaatcca agaattaatg tacatgaaac
    86341 tgcaaaacca tatgtacctt gtgcaagtgc tgtagctgct tctggtgaag ctataacacc
    86401 agtaattcca aagccatgtt ggaacagttt attgaaattt tgaagtgctc ctgtcatagc
    86461 agaggcacca ataccaaata tcaaaaaacc gataagtgtt tttgaagagc ctgtaaatac
    86521 ttcaacagct gatttctttt gaagaatcaa tcctatacat gcaactacgc caagcaaaac
    86581 agcaggtgta ctcagcaaac taataataaa ctccataaat attcctcctt atcatcttaa
    86641 atttatccct cttttgaagc aaggaatttt tctagtgctg tctttatttc attacggtca
    86701 acaatattgt gaatcccaat tatatcaaac ttcaaatttt tattttttaa ttcttcagca
    86761 acatcaatta atgtttctac agcatctcca ttgaatccat ttagtgaatc caatgaacca
    86821 tgctctactt caattggaaa gttattttcc ttaataattt gttgagtctt tatttttaac
    86881 attaaacttg agccaactcc tgctctacat gcgattaaaa ttttatacat aattaaatcc
    86941 tcctttataa ttcgtgtgtt tttataaaat caataatttc tttagcttct ttagcactat
    87001 ctaaaacctt aaaaaactca tcttcttcca atagttcaac tagctcagac atagcacgta
    87061 aatggctatt attgtctatt gcacttagac aaaatacata ttttacaggg tcgttttcgt
    87121 tattcccaaa ctcaatagga ctatctaaag tagcaatgcc tattgcaatc tcttttgacc
    87181 cagcttctgg tctagcatgt ggaagtgcaa catgttttgt aattactatg tatggtccag
    87241 atgcttttgc tgagttaatc atagcatcta catacccttc agttactttg ttattttcaa
    87301 ctaatacaga agctgactgt ctaatagctt cctcccaatt cttagctttt acctttattt
    87361 ttactagtgt ttcattagta atctcactta gcataggccc ctctccttcc ttagatgtaa
    87421 aattctctat ctgtgtaaaa taagctaata gctcacttga aagaatactt tcagaggtta
    87481 catttgcata tttttttatt atatccataa cctcatctat tttaggttgt cttaaaaaaa
    87541 tatcacctaa ttgaatatac acttcacgtg taatcttata tttttctttt gtggtcataa
    87601 cagggcttac tttaattact ggtacatctg tttttaaacc ctctgcgtta taattagtag
    87661 taaatacaat atctacaggt tcacttatat tttctaatcc aactgattcc gacattggta
    87721 taaagtgtaa gtcaggaaat aagtttgtaa gttctgcatg taaaatagct gaactaccaa
    87781 cgccatttga acaaactatt aatgctattc tttttctaaa accatcaaat tcttttttat
    87841 ttgaaaaaag tgttgcaaag tgcattgtaa gatatgctaa ctcttcttcc tgaatttctt
    87901 ctccaaataa tccgcaaaac tctttcattg cattacttac aattctataa actaatttat
    87961 attcttcttt tactttttca caaatcggat tatagatagg taatttaaat aaaagtctat
    88021 agtaggcagg tctaaaatga gaatataatt gtttaaatat tttttcttgg cttatatagt
    88081 aaactccgct taaatatcca aactttgtca tcattttatt tacaattttt gaaattacat
    88141 ccttatcttc tgtatcttct tcataatttc ctactgatat acctaaaatc caagcactaa
    88201 tatacattat attgtgaggc tttatcttat cttcactccc atatacttct aataattcct
    88261 tagcaaattt atactccttc attgaactca taactgaaat attaggaata tctacatttt
    88321 cctgagtaac tattctagtt gaatacatcc ttgcttttag aaagataaat atatatataa
    88381 attctattaa tctatcttca acaaaagtaa tttcatattt ttttattagc tttaatataa
    88441 tttttttagc ctcttcaaaa ctatctaaat tatattcttt aataaaaata tcaaatactc
    88501 ttgaactttt ctcattagac aaagtttcta taatgttttt aataagtact ctcctaattt
    88561 ccatctcatt gccaactatg taatatccat ttatacgatt gttcttaact ttaatgttct
    88621 tcttttcaag ctctggtatc aaatccttga aatcaagatt tacagtagac ctacttactt
    88681 ttatagaatt tataaaatga ttaattgaaa tatcctccat gttaataaaa agcattaaat
    88741 acatatataa aagtctttct gtcttactaa aataataagt attcttagaa tagttttttt
    88801 ctaaaatttc tttaattgct ttttttgttt cttttctaac gataatatct ttgtcggctc
    88861 ttaaacatat aagtggtaca ttttttactt taagcatgtc attgatttta tttattctat
    88921 aagtaatttg tctctttgat gaattagact cctcttgtaa tccattagtt gtaatcaatg
    88981 tgctatttaa taaaatctgg agaattgata caatttcttt gtccactacc attaacccct
    89041 actttcttat taagattagt cttcatatta tcattggatt ctttcatcac ctccacaata
    89101 cttattttat ttgagaattt tatcgttttc aatttcattt aagtataact tttgttttag
    89161 attgatacaa aaattaaact catctaaaat agatactata atataactgt agattttata
    89221 aataaaaaaa gtttctttag acaaagaaac tcaagaaaaa ttgatttaaa taataaaaat
    89281 catattgatt ataaataaat tactacaatt aaaaagcaca ttaatttaaa ataaaattga
    89341 tgtgccttat ctataatata atatatttaa tctaattttt aacttggaat ttaacatcct
    89401 tttttatgaa atcaacttat gtacatatac aattcatact ctatttttat ttcatttttc
    89461 taagtgtttc ctctaatgaa atacacttcg catatctttc attccatata aattcattgt
    89521 agtatttata tgattgttct gctgacataa aaaaattgtc aacagttgta tttgaataag
    89581 ctggaactat tatattaaat ccatgttcaa atccacattt tatagtggca tcaatacaat
    89641 aatctgtttg gagaccagca ataataatat ctttttcacc attatttgtt aggtattcta
    89701 atagaccagt ttctttaaaa gcactattta cttttttatc aaatattttt tctccattac
    89761 atggtttaaa tttttcgtat atttcaaagc catttttacc tttagtcaat tcattttcaa
    89821 ctccatcatc atgacgtaca tatattactt ctatattatt ttttctagct gtatcaatta
    89881 aattttctac atttactaca aattcattaa atttatataa cctctcgttt gttattaact
    89941 tttgtgcatc aacaatcagt aaaaccatgt ttattcctcc ttggatgttc ttctaataat
    90001 atctttatat cttaccataa agatatatat tactctctaa tatttttata taatacattt
    90061 cctggattta taactattaa tgcaattgca aatattaaat ataacattgc atagtaattt
    90121 ataagctcta ttaaatcttc attaattatc cctattaaaa aattaaatag ttgatgtatt
    90181 gcaataggta ttatcaaagt tttatttaga ttataaaaag ttgtcattat aatactgatt
    90241 gatataattg caatcataaa aaatataata tattttatta aatcaagtcc tttgaatcct
    90301 gttgtaaacc atattggtaa atgccacatc ccccaccaaa aacctactgt tatggatgct
    90361 tttaaaggag aatgtctttt ctgaagatga ttttgaacaa atcctctcca acctaattcc
    90421 tcacctaatg atcctgcaaa taaatttttt aaaaataaat atataaatgc tccccatgat
    90481 gaaactgtaa agttaggcat tattccatga tttttagatg ctaatataaa tataactact
    90541 acagctatta ggacttgtat actaattatt atagatactg ttgaaaattt aagtttattt
    90601 ctaaatctat cttttacatg tactaaaaat ttcttacctg gataaatttt tttaaataat
    90661 atcataaatg caaaagtgga tgaccacgct gatatacaca acgcaatgtc agatatcact
    90721 gttggaagtt ttaacattat agtcactact accaataaaa aaagtggtaa aaaaattata
    90781 tttgttagaa taataaaact ggctataggc ctttttaatg atttctctgt tctcataagt
    90841 aatcctcatt tcaaattaat atttaattgc tatataagtt ataactgctt atatcatgag
    90901 tttaaaccta tgagtaagtc ccaggtcaat gcttttatat tattttatag gtgcataaat
    90961 ctctaaaaat atacgctcaa tcccttcttc ataagtagta agcaatatat taacatagac
    91021 tattccaagt aattcacatt cattttctat tgctatttct cttaatctgt cttccacttt
    91081 attatcaata ttttctcctc cagttgacca tctgccatct tcaataatag tataaataca
    91141 attgggatga gatagaactt caccttctat gattttgttg tagtcatcta cttcccttac
    91201 aattataaat ttttcttcta ttataccttc ttcattaaaa tttattactc ttcttaaatc
    91261 agttaatgta actgcttttt ttaagttgtt tgtattctct tttaaggctt catattcctc
    91321 atagttagta acatgtttta ttttaccttt tacttccaaa ggcttcattt cttttattgt
    91381 gtattttcca aaatatgttt tgattttgtc acaatcttct ttgactaact gaaccttttt
    91441 taagagaagc tttttatatt ctatctcttt tagtatgatt tgttccttct cttctagtaa
    91501 gagttctaaa ttgtttatac ttttactttt tcttatttct tgaatctttt taatttctat
    91561 atcaatttct ctataaaagt ttattgttgc aatatcatag atatcaacct gattatatat
    91621 tctatatcca ttttcatcat ttttcttagg atttactaat cctttgtctt cataaaattt
    91681 tagtgtatct ctagatattc ctaaaaattt agatacttgt ccaattgtat acattatatt
    91741 ctcctattat tagataaatt ctttatgctc attaaacgta tttctattaa caattacaaa
    91801 atcacctaaa ctttgaagta tcaaagtcag catagtattt acaaccttta gaattactct
    91861 ttttatttca taatccaagt gtaaacttgt taatatgata cgttataaat actatattgt
    91921 ctacatattt ctaacaatga ttctttcact ttaagatgtt cttaaacata tttaactttt
    91981 atttttaaaa atttcctata cataaaaata ttcctttcat gataacagtt ttattatttc
    92041 aactatctgc taccataaaa ggaatatctt aatctttaaa cacattctaa atgctctttt
    92101 aacaaatatt atcaaattat tctaattcta ttgtttcata tttattagtc ttagttttat
    92161 ataaatttaa atataaaact atatattcac ctacttttaa ggatacaata agtcttcttc
    92221 taccagtaag agtaaatgcc ttctctactt atcacaaact ataattttta tctcattggt
    92281 atatatccac gatactgtga gtatgcatcc atagttgcta tatcacctaa gaatactgat
    92341 gcgatattga attgtggttt taaatatggg aactcctctt cttgtgccca ttctggtttt
    92401 ttaataaacg actttgtctc ttcaaccaca gctttatacc attcttcttc cccttcaaac
    92461 catagttctg acacacggtc aaaagcagtt gctccataat taatcattat tttactactg
    92521 acaaaacgat taacatagca acagtttgta aagtatggca ctacctcatc atagaaccat
    92581 ttttctcctt cttctttaga gataccatct ggatacttaa tcataaattg ccaacgatag
    92641 tttggtccat cttgtacagt acgtcctttt cctctaaagt cttcttccca gtttattgga
    92701 acaaaggcaa atataaatgg tggacatcca ttatctccac ctactgcacg tcctgcatct
    92761 ccactttctg cattttcatg aaccctttta ttttctacat ctggtataca cccttgccaa
    92821 cgtagaacat ccataggcat atattctgtc ataattctat ttgccatctc aggcatatgt
    92881 tcatctacaa gccaataatg ttctgttagt tgcatcttac gtgcaccaaa acgctcacct
    92941 tcatttggtg taggatatgc ttgataaaag gcatatttag tacaatatgg tccaaaagtg
    93001 ctaatactat ctggaatatg gtgacgatat aaccagtcca ttagcttagg tctatattct
    93061 tccttggcaa gtcctacata tattaaactt ctcattattt taaattcaaa acccatagcc
    93121 atcctcctat aatcaaagta tattcacatg ctttcaattt ccctttttcc tatctttact
    93181 caaaatatat attgtaaaca aatctacacc tgcacccacg taccatactc ctactgccat
    93241 agctacagca atttgaatac aaatatcttg taaattaata atattttcac ctgtcataat
    93301 agttagacct atagcccaac cacaaagcca tgatggtagg aaaattattt tttcaaataa
    93361 ggatgcaatt acaactgcaa aaaaacctaa tatactaagt gttaaaaata attctaggtt
    93421 ttgattgaaa ttcatatatc ccataattaa aatggctaac actgcccata aatctccaca
    93481 ccaaaaacca aacattattt ttaatccatc ttcttgttta ttaccattag ttacatataa
    93541 tcctgcacag attagtgcta cagctccagt ttttattcct atataaggtg ctaatactgc
    93601 ccataaagga ggtagtaaag caatccccat agacagtgtt aatatttctt ttttctttct
    93661 atccatttcc tatattgtaa ttagtagctt ccctagcttg ccttatctcc aatagcttaa
    93721 ttgctatttg atttacaatc atagatactg caaaataact taaatatagt ggtataaata
    93781 taacaataaa tgctggagtt aatctaacct tgtaatatgt aagtaccaaa aaaataactg
    93841 ctaaaataac ttcaatttgt ttaaaacttg gcttttcatt catacaataa gcctcctata
    93901 acatctaaca tcccttaaaa aagagtctta gtattttaat tattatccta atgaaactcc
    93961 agcttgtttt tctttagtta atgtctctat aaaattataa gatgtttttc tttctttaaa
    94021 ttcttgtgtt ttacgaactt ctgcataatg accttccatt ttcttaatat catcaccatg
    94081 tataaactta cctggtaaag tatcatgagc atgacctaat tgctcttctg gaaaactaaa
    94141 tatagttttt ccacttatag tatctaactc tccaactata ccacatagag cacaaattgc
    94201 ctttttagta cctggctcaa ggtagaataa tctattgtgg caatgtggac atacaccttc
    94261 ttctccttga tatgaagctt tttcaaaatc ttttgctgct tcaactatat ttaaaccaat
    94321 ttgatgaact tgaacaagcc ttgtatcatc cattactaat tcctttgccc atgggaacca
    94381 agcattatct ataactttcc acattggtat gagagctagc atagcatgtt cacattgaac
    94441 tcttgtaccc cagtcagaac ctcctattcc cataaatgat attactttat cattaagcat
    94501 tcttgaatct ggaatttttc ctcctatagc ttctgcaact tttgttccta taatgttatt
    94561 tcctctatct gctctgggtc caaaacggtc cattatagta tggaataatc ctgatgcccc
    94621 ttcttcaaaa atagggtctg aaactactat accatctgca tctttcattt tgtcaagcaa
    94681 ccattcaaaa tcatctttta atacacacat actacctttc ccagataata aagttttaac
    94741 acacgcacaa catccagtac aatgtttaat gttaatagat gacatttgaa taaattctac
    94801 ttcagcccct gcttctttgg cacctttaag tgcaacttta cacattgtgt cattatttcc
    94861 attttttgtt ccaaaagaaa tacctagtat tttcattttc aactctccct ctttagtatt
    94921 tatttaatct tctttcattt ttaatatata gaatccatca tctaaagcat ctatgatgat
    94981 gtagcctcta tcatcaacga taagatcttc tgttactgcc aagcgtggtc ctgggaatcc
    95041 tgggaaataa gattcttctg gtgttttatt tggatttggt ggtataaaat atgctagctc
    95101 tttgatataa tatgggtctg atacatcata aacccttagc cctgcatgga aataacagca
    95161 atatactcta tctcctcttt gctctaacca tggtttatta tccattggtt catgaagatt
    95221 atgtggacca aatggccctg gttttcctaa tcctgcaaca ttaaagttag gataagggaa
    95281 atcttttgga acttcaggat atggaaattg agcaattaat gttggttttg ttgggtcact
    95341 aacatcaacc atatgtatat tattcatagc ttgaacatct gtaatgttat ctggtttaaa
    95401 gaactggaat ctttctccct cattttgaac aacgactaaa tctcttcctg gcaatggtaa
    95461 tgctgtatga gttcttgcac ctgcaagtct actagaaaat gcaggcataa atggcaattc
    95521 acctaagcat cttggtcttg ttaaatcttc aacatctaat acaactaaac cagctcctcc
    95581 ataaccacaa tatgcttttc cgtctcttac aaatggaggt ccatgaagcc atcctttatc
    95641 cataaattct gggcaatgag gtgctcctgc atcaaaagtt ctatttggat atccatctgc
    95701 atattggtct ggtctccacc atttacctat ttccactgga ttagtaggat ttattatatc
    95761 tatgacccta taaatcagac cttcaaagcc aacacaatca cttgataaat gtacatatct
    95821 tccaccattg tacatgaatc tatgaacacc cattacatgc tttaagccac aatcccaata
    95881 tcctaaaaac ttaggattta aagggtcttc ttttaaacta tatattctaa ttcctgcttc
    95941 acacttaata tttgctaatt tagcttggtc aacaagtgct cctggtccac ttccacaact
    96001 cattgctact atcattaaat catctgctat ttgaattttg ggagttgttg ttgtaggata
    96061 ctctttaggg tctaacattt gaaaatgttt tataaattgt ggattataag ggtctgtaat
    96121 atcgctaatc attactccat tttttttatt tcctccaaaa cagcatccat ataaatagta
    96181 tttttcatct cttttgtaca gagccatttg aaacattcca caagttccat ctaagttatt
    96241 aaaggaacaa acttcaagat ttttaatata tccgttattt ccgttgcctt ttgcataaaa
    96301 tttatcttcc attttttctc ccttcttatt taaagtatta tcaattgata tactttcatt
    96361 ttatgagaca aacttactta aatccaatat cgttttcatt ggaatatata agttattctt
    96421 attaataaat ttataaaatc taatgtaaag atatacttaa aacatatatt tttatacaaa
    96481 tattttctaa tattctttaa aagtaaattt tcttatacta taataagctt taattataga
    96541 taaataaggt ttacaaacaa tcaagtttaa ataggggtga ttatttgaat actaaacaat
    96601 tagaatattt tatatctgta gcagaaaatt taagttttac caaaacagca gaaaaatttt
    96661 atatttctca aactgctgtt acacagcaaa taaaagcttt agaagaacaa ataaatgtaa
    96721 ctctatttac aagaagtaaa cgtcatgttg aactaacacc agctggaaaa gtttttttat
    96781 ctgaggcacg tactataata aaaaatatca atgatgctat tgcaaaaaca caacaatttg
    96841 cacatggttt tttggaactt tgagcattgg aaccttaata ggatatgaaa aaaacaaact
    96901 tcaacaatat ttaaaagaat tttctaatac ataccctaat atatctatgg atatttgtac
    96961 taatgaaata accgaacttt taaacttagt aaaaaataat tctatggacc tcgcttttgt
    97021 tattaatcca gaaaatcaac cattaaaaga ttttgaatat aaaactgtag aaagatattc
    97081 tttggtagct cttttacctc ctggtcatcc actttacaat gaggattcta tcgatttaat
    97141 tgaattacaa catgataaat ttatttttgt aaaagaaaca ggggatgagt atggacaaaa
    97201 gtcaatgata cagaatagat atcgtgaagc agggtttgta cctaatgtgg tacaacgttc
    97261 aaataatctt aatactattg aatcattggt atcttctaac atgggaatat ccattttacc
    97321 ttcattttgt gttacagata caatgataga acgtgatatt gcaatagtac ctataaaaga
    97381 agtagaaaat agaattgaag ttgtagttgt atggaataaa aaaaatacaa atccagcatt
    97441 agaaaagttc atttctataa tataaaatta atcaatatta acgataaaaa tagcattaac
    97501 cattttttct atagttaatg ctattttcta ctattttatt atttaacttt taatttaata
    97561 tttataatca ttaaaaataa ctctgtttaa caaatataaa caagtcaaaa gtgtgtctaa
    97621 aaaagataaa aattttatta tatacaaatg tattatctca atatatctat tttttcattg
    97681 ttcataagtc taagtacatg acctgtgctt actaaagaat tatccccata agttgtatga
    97741 gctaacaccg aactagcaac cccaaactca actatatctt cactcttcat attttccaaa
    97801 tatgaatata taattcctgc tacatatcca tctccggcac caaccctgtc atatatttct
    97861 aacttatact ccctactttc aaaataacca tcatcatttg atatatatcc ctttataaat
    97921 ctattattca tatcatcaaa tcttctcata gttccagcta caatacctat atcatactct
    97981 tttttaatca attctgaact agattttata tttagactat ctatattaag tatcttattt
    98041 atatctctat aactagcaaa tagaccatga caatatggta gtattttctt ataatcattt
    98101 actaaatcat cataagtcct ttctggattt aatgattgtc taaaattaaa atcaaagaat
    98161 acttttatcc ccttttcata agattttcta gctagttcta aagcaatctc tttaattgaa
    98221 tctgtaagtt gcatagcaat accacaaata aggactatat ccatttcttc taaacattta
    98281 tcaatatcat aatcttgtaa tttactctca caaaatgaac tatttaacct attcaaataa
    98341 gtcacttcag aaggtctttc tccataccca ttttcaagaa aatacactcc tatatgattc
    98401 cctccatatg tgataaagtc atcttttact ccaagctttc ttatatttgc acttgatgct
    98461 ttacctacat tattattagg caactttgtc aacatatagg tattgtatcc aaagttttta
    98521 agtccagata atatatttaa tcctgtgcct gtaattatat aatttagttc attggtttgt
    98581 gttaagaact tgtagtcagg tactgaaagt ctcatcatta tttcaccaaa agctaatata
    98641 ttcataaatc tatcccaata attctttcat tattttataa agtactccta tatcttccac
    98701 tttcgtttca cctgtttctt tatcaattat tgatgtataa acatgaggta taactttttc
    98761 tacaccagca tcaagtgcaa tttgaactat ctctttgaag ttatctaagt ctataccccc
    98821 tgttggttct aaataaaaat tatgctttgc acaagctttt gcaacttcta tatattcatc
    98881 ctttgtttta agccctccca ttggaaaaaa cttaattgag cttcctccca tatctttcat
    98941 catagctatt gctgtttcta taggaactat accatctttt tcttttgaac ttaatggacc
    99001 tgtggatatt tttacaaatc ctggtttacc agttggagaa actaatccat ttattatact
    99061 atcattttga ccaagcaatg ctctagacgt agccacacct gtaaacactt gatttatatg
    99121 ttgtggctga agttctttag aaatctgaga taccatattt gactgatttg ggtctccagc
    99181 tccaagcccc acagatattg cattatctat ttcctttgag tattttttca tatcttcaat
    99241 agctgcttct acagtactgt aattctttga tagtactcct atcaatacat acccatcaca
    99301 agcatcatat acttctttag cattttttat gcttcctgca agaacattta aacaaactct
    99361 atttttataa tattgtggta tacaattcat atttatcccc tccattggta aaatttaatt
    99421 tattaaatca ttataatgtc acttactcta cactctaact ttctactata ttttttatcc
    99481 tattataaat agtatctaaa tcacttccag ttacacttct tatatcaatc tcaatcttgc
    99541 cttcattagc cttatagtct ctagtgtata tagctatctc tccacttcta agttcattta
    99601 taatttgttg tgttgactta tttattatat cttcattaaa gtcaatttct ccacgaagta
    99661 tttctctacc tgctgaatct ctagttatac tagcactcac tccctttata gtatttatct
    99721 tgtctataaa tggatttagc ttgtcctcca tttcttttaa agttacttta tcattactta
    99781 tatatctctc aattgcacat gttagaccta caatattttc ttttcctatt ttcatagctc
    99841 ttcctatacc ctttgattga agctttacat tatctatgta ttttttctta cctattacta
    99901 accctgagct aggaccctct atagccttag caccactgta tatcactagg tctgctccca
    99961 attcataata tacatttaaa tcttcttctg ctgctgcatc tactatcaaa ggtaaattat
   100021 attctttagc aacttgtact gcatctaata cacttagcat actcttttga acacaatgat
   100081 gagatttaat atacataatt gctgctgtat tttcatttat ctctcttatt atatgttcct
   100141 tgttacacat attagcatag ccggcctcaa caacttctcc tcctccaagt cttatcatta
   100201 cttctactgg aactccataa tcaacattat gcccctttgg aattattatt tcccttttaa
   100261 cttgtttctt aggattattt acattgtaaa ctagactcat atcatctttt gctatcattg
   100321 ctcccacact ctgtgcaatc ccagcagatg cactagaaac tattagtgca ctttcacacc
   100381 ctaataaatt tgctatatat tcacctgttt tatttataag ttcttctatt ataaagaaat
   100441 ttttacaccc ttcacctatt gcttcaataa cttccttatc tactgttgat actcctagta
   100501 tagtcatttt gcctgaagca tttataacac gtcttacaga gtatttttca aatatactac
   100561 tcatacaata gtttctccct tctactcatt ctctcctata gacttaccta tatttaaata
   100621 ttctccattg actactactg ctcttggctt tatagacgta cttgtgatta ctgacttatt
   100681 caaagaatct tgaagttctt tttcttcatt aaccacatca aatatagtta aatcagcatc
   100741 atatccttct tttattaaac ctttattttt taaacttatt gcatctgctg catttttagt
   100801 aactttatct attatatctt caagtgaata gcccatatat ataaactttt ccattgttgt
   100861 agatagatta tacactggac catttattct atttttaata tatatatctg tacttatagt
   100921 gtctggaaaa attcctgcat ccttagattt cattgcaata tccatactaa aactttcggt
   100981 tccatgacct acatcaagga ttatacctct ttctctagct tctatgattt cttttttaac
   101041 ctcattgcct ctaagtattc catttggctt tccattatat atatgggtta atatatctcc
   101101 tttttccata tagtcaaata tatcctctat cgttggagga gaactcccaa agtgaaccat
   101161 cataggtaga ttaagttcat tttttattct tttagctact tttaaaggtt caacatcatt
   101221 tgaaattaca acacttttac tcattctagc tttgattcca acaacaaaat ctttgtattt
   101281 tttaactgct cttttaagtt catattcatc aatattcatc atacttgaaa gttcatcttg
   101341 agatgttatt ccctgcttag caatatttat taaagcatat acatttgttt tatatttttt
   101401 agtatcttca taaaatttac ctatatctaa agctcctgtt gttcctgcat ctactacagt
   101461 agtaacaccg ctttttattc caacctcatc tggataatcc ttataaaggt ctagtctttc
   101521 gtagcaatgc gtatgtatat ctatccaacc agcactaata aatttttctc catctaggtt
   101581 tataatttga tttgcctgat acttagaatc atctatctga ttttttactt ctattatttt
   101641 atcgtctaat atagctatat caattatact tttatctact gtttttccac cttttattaa
   101701 tatgtctatc ttcactttac tctccctcta aaataagttt aaatttactc caaggttcaa
   101761 taaagtctaa aagcattatt tcgtcttcct ttattctacc taccttattt tttctttcat
   101821 ctgcacaatc ttgaagtatc aactgtaatt cccctttata ctttccaaag tcatcattac
   101881 caatcactac atctcctctt ttaaagatgg tcgtattatc atgcttaggg aaattttctt
   101941 tagcatattt ttttcttact tctgtagacc ttgctacttg gttggttata tcccctcttc
   102001 taaagtgttg ctcatttgcc attattgtct tttctacttc agaagttttt tcctcagtta
   102061 ctacattaaa tacaacttga tatttattta cttcagacat tctttttaat tcatcttcac
   102121 ttgcatatgc attccctaca attacatcgt caatcaatcc tgttgcgaat aagtgcttag
   102181 ttgctgtagc aatatctaag tttctatgca tttcaagcgt acacagtcca tcatttatat
   102241 tccaaggtcc gattgttgca tattttgaat taacaaaagc agcagttctt attccatact
   102301 ttttaaatct atttgaacat cttacaaaaa aatcatatgg caagcctgta cccctttgag
   102361 gataaaaatt gtgacaacca tatatattat ttacatttgg cttgtaagta attatattat
   102421 ccaagtatgc tacatcatta ctcatattta gttccacttt taaatcatat ggattgaaag
   102481 aaatcatagc ttctttactt ccatcatatc catagtcaag ccttattcca ctagcattta
   102541 actcactaaa aaatgttaaa tcatcataag atatttgtaa tatatcaaat atgtttggag
   102601 ctatatcaag gattacttca aatcctaatt ctcttgcata ggttataatc tctttaaaat
   102661 gttttttaac ttcttcctta ggtcttgtaa ttgaaagcat gcacataaat attcttttaa
   102721 atccgtattt tgaagccatt tttatatatg ccttatcatc ttccatgtta ctatgctctg
   102781 gatatactga tattcctaat cttctttcca tctttctcct cctcaaatta cattatttaa
   102841 aatatataaa attaaaggca aaggtcattc ctcctacctt cacccttaat aacttataag
   102901 ttttttctat attttatata gtacaaaacc tctatatcta tgtattttta taaattttca
   102961 ctcatttctt cttgttctct ttgtaattgt tgtttttcaa aaactttgaa gaatggataa
   103021 taaacagcaa atgatatcac aaagttgatt aatactaaga tacctgctaa tatactccag
   103081 ttagtactca ttactgctgc tattggtgct ggcattgcaa atggtaatct tgctaccatc
   103141 ataggtataa cccctgtaat agtaagaaca tatgatagaa ttgtcattat tataggtcca
   103201 attataaatg gtatccctag tattggattc ataactattg gtgctccaaa tattataggt
   103261 tcatttatgt tgaataaccc tggtaaaaat cctaatctac ctaaactttt tagatattgt
   103321 gacttagaaa acataaacat tacaactaat gcaagagtag cccctgctcc ccctatccat
   103381 acataccact gtaaaaattg ttctgtaaat atgtttggca ttgcatgagc tgatactcct
   103441 tctgtgaatg cagttatatt ttctgctata gacatgtccc atataggtct tattactggc
   103501 cccattatag ctggaccatg tattccaagt acccagaata aagttattag gaatactgtc
   103561 agtaacccac cacctaaact atttcctgat aagaatcctt ttaaaggtga taacatagcg
   103621 cttagtgcaa cacttatatc aaatcctaaa atatgtctta ttacccagaa taacattaaa
   103681 attactgctg tcggtaataa tgcagtaaat gaatttgaaa cctctactgg aactcctgct
   103741 ggcatcttaa ttgtaatatt cttttccttc ataaaacgat atatttcaac tgtaattaat
   103801 gatgttacga tagctccaaa taatgatggc gaattaagtt ttgccatatc catccatcta
   103861 ccagcttcta taactccacc tactggttca actacttgag ttggaactat tgtagaaact
   103921 aaaaatgcca taactgcaag cataccaaca cctgttgtat ctaaatcgta gcttttagca
   103981 agtgatgatg ctatcccaaa agtagcatat agagataaaa atcctacagt atatctaaat
   104041 ggtatatcta atattgcttt aaatggagct ataaaatcca tataagcatc aataggtatg
   104101 tttaataata ttgtgaaaaa tgaccccact attgttagtg gtaatgttgc tattatacct
   104161 gctcttacag ctctcatatg tctctgatta cttatcttcg ctgctacagg cataatcttg
   104221 cgctctaaaa aacttgcgaa tttttccata gttatccccc tgtattattg atattatcct
   104281 ttatttataa tgcaataacg atttcataac ataaactaat ttttatgtaa ttgataatat
   104341 cacttgttta ttaaaaatat tataacatta taatgtttag ttgtaaacat tataatgtta
   104401 taatattttt tatttttaca actaaacaaa aatcctgagc atattatcat ttcaataaac
   104461 tcaggattct tattatattt cgtatttaat tacatagttt tgtacttctg tattatatct
   104521 tgcaaatgat agctcaacta tattatcatt ctcatcatag gtctttcttt ttcttcctaa
   104581 taatatgtct ttagctagat ttagagcctt tgatacctct agttctgatt cttctataaa
   104641 aaattcatct tcaaatctag ttatatttat atttctccta tataagtaca tatataaaga
   104701 actttcatta ttaaaacttt caacagttag attttcatca aaaggaatat aatgagtaaa
   104761 aaatatatat ggcttactat ctaagtaata cattctagta atcttgctac atttttctcc
   104821 aaatatacta aatacttgtg aatttgtatc atttattatt ttttcaattg aaatagtctt
   104881 tttagataac ttatgacctt tagataaaag tatacttgaa aaagactctg cttttgatag
   104941 cttattaaaa agactattac ttattacttt tgtccctttt ccactttttt tctctacata
   105001 cccttctgat tctaatatct caatagcttt tctaatagta attttactga ctccaaactc
   105061 ttgctctaac tccctttctg ttggaatatt ttcatcaatt ttatattcgt tatttaatat
   105121 tttttgcttt aatatatcta caacttgtat atataatggt tgatttctta acatgattca
   105181 cctcttaaat tatatgttat aatattataa catataatct tatattatta ataataaata
   105241 tttattaact ttaaactaaa tataaaaaga gtcctcaaaa taatcctaat gtattactca
   105301 ctaaatattg aatcaataat ctaacaatta gtgtgctaca cataatgtat cttttaagaa
   105361 ctctcttaat ttattatctt taatttttat ttatcttgta atttcaaatg taaatcaacg
   105421 atttcctcag ctaactgttg aaaattcatg ccattcatta agtggtcctg tgcatgtata
   105481 agtatgacac ttatttcagt cctgtttcca ctagcttcgt tttgtattaa ttctgtttga
   105541 tatctatgtg ctttatttat aacttccctg gactctttta ataattcttt tgctttttct
   105601 atatttccat tcttagcctc ttttattgct tcaaaagcta atcctttacc ttcacctgca
   105661 taacctatta tattaaaaga tatttctata gtcttttcat ccatcctttg attctcccaa
   105721 tttatatatt aaaaatacat tataatttat attacttagt gttgttaagt tctatcgctc
   105781 tatttaaaac agcttctcca ttaactgttc catagtgcat catatttata acttctactg
   105841 gtatattata tggcttagca atttcttgag ccttaggtaa tacatatcta acttgtggtc
   105901 ctagtaataa tacatcacat ttttctattt cattttgtat agttgattct ggtattgccc
   105961 aaatttgcga ctctatacca ttttctttag ctgcactttc cattttagta actaataaac
   106021 ttgtagacat tcctgctgaa caggccaaca ttatttttat catatatttt cctccaaatt
   106081 tttattaaca accatataaa cattataatg ttataatatt ttatttaatt ctaccttaaa
   106141 tgcaatatac tttcaatact tttttgttat tttaatatta ttaagtgtca aattaacaaa
   106201 aaccgtatca tttatttatg atacggttct ccattattta tcctataagc cctataaatc
   106261 tgttctaaca atatcaatct catcatctga tgaggaaaag tcatcttaga aaaggataac
   106321 ctataatcag cccttcctaa aacctcatca gaaagcccta aagaacctcc tattataaaa
   106381 cagagactac tattacctct aactgctaaa tcactcatag tcttagcaag ctcttcagag
   106441 gataaaccct taccatcaat agccaaggct ataacataac tattatgctt tatcttccct
   106501 aaaattttct ttccttcttt gtcttttata atttccattt ccttaacact caaattctct
   106561 ggagcttttt catcatccaa ctctataatt tctaacttac aatacttaga aagccttttc
   106621 ttaaactcat caatacctaa ttttaaatat ttttctttaa ttttacctac tactactata
   106681 cttatattca tatatttctc ctaaacttaa ttttattaca aatctatgca ttactagaat
   106741 ttacaagctc ttataaaatt atatctctct ttcttgattt gcatattcta caaactcttc
   106801 aaaaggtatt gctttgctat aataatatcc ttgatatatt tcacatccta aaccatataa
   106861 cttatccctt tggtctatat tttcaacata ctcaacaact atatcaaaat ctaaattttt
   106921 tgaaagattt acaatagtca ttataatttc actacttctt ttatttgtaa gtatctcttt
   106981 aactaatgaa ccatccaatt taactatatc aaagttatta ttttgaagat atataagaga
   107041 gctatgcccc atcccaaaat catccataat taactttatt cccaagttat gtatcgcatt
   107101 gatacgttca ataattattt gtgaacctga taatgcaatt tgctctgtta tttctatacc
   107161 taacatatta ggatttatat cattactact aatgatattt tttatttgct ctggtaactt
   107221 agggtcatca agttggtctg gagatatatt tacagagaac ttaacaggat ttctcaatag
   107281 cttttcactc ttctttaaat caatacatgc tttattaata atatactctc caagctcatc
   107341 taagaaccct tcttctttag ccaaaattat aactagtggt ggataaatga accctcctat
   107401 tgaatgtttc catctaagta atccctctgc tcccacaaca tttccattat aattgacttg
   107461 tggttgataa aaaagctcta tttctcctct tttcatagca aacttcaagt ctgatgccaa
   107521 catttttgaa attgaaccta ttttaccatt atggtttaga agattaggct gttcacctgt
   107581 taattcatac ctttttaata agtttgttaa attttctata ttatttttaa acatatatgt
   107641 atatctattt tgcgacattt ttataaacgg aatataaatc ataacaccaa cacataaatt
   107701 aaatacttgc aacaaactac ctcttattga acctgtagac atatatccac ttaaaaatat
   107761 aggtgaggtc cattctacag ctgaaactgt acatggtaca atacctgtag acatagccac
   107821 ataacttgta acggttaaga ttataggagt aattacaaaa ggtacaaaca taatatagtt
   107881 aaaaacaatt ggtatcccga aaactagcat ctcattgata ttaaaaagag ctggtattga
   107941 agcaatttta gctaactttc ttacatttat acgtttttca ctaagaaaaa ttgcaattac
   108001 taaacatagt aaagagccac atcctcccaa taaaaccatt gtatcaaaaa aggtcttagt
   108061 aaaaatttct gttggtaatt gattattatt aactaaattt atgttaattg ccatactatt
   108121 ttcaaataaa ttttttgcga cggtatctaa tacattacta ccatgaatcc caaaaaacca
   108181 cataaagtgc attaaaaaaa taaacaacag agcactcata aggtttgttc ccattttatt
   108241 aaaaacattt gaaaataaat tataaaatat atcttgaaag tttgaactgc caattagact
   108301 tatcattacc actctaaaaa tagaaaacaa aaatactact attatgaaag gaactatagc
   108361 cgaaactacc atattaaagt ctgcatcagc cccttctgta tgaaacttta cacttgtaac
   108421 aaaagattct gtaagtttta caaacaatac agaagatgtc atagaaacaa ttatagatgt
   108481 aaataaccac tttgttttaa atatttctat ataagaatta agctcattac catgtgaaaa
   108541 tactaaaaaa gagcacattg caactatagg aacaagtact gtatacttgc tcccatatat
   108601 ttttccataa ctatagctta ttgttaataa tattattaat gaaataattc ctaaagtaga
   108661 atcatttata aagttaagaa tatttgtaac ctctccatta aacaagcctg ataaatattc
   108721 ttgataagcc tttattggaa gattcaaaat tacaagagca gttgaaccag tcataatagc
   108781 aggtatcgct aaaatcatac cctgctttat agagtataaa attttattat cctcaacatt
   108841 ttcaaaattt ctctttagca aagttattca cctctacttc atctcataaa cattagaaac
   108901 atcatttcgt gatagtacat ctagttttac atcttgtcca actactatat catttgatgc
   108961 taatactcct tttgaagtct catacgctaa ctcaggaaaa ttattttctt tgcttaaatg
   109021 tgctaataat atagattctg taccttcatt aataagttca acgcagaaat tagctgcatc
   109081 ttcattggat aaatgaccag tacttgacat tactcttttc tttaaagcat atgtatatga
   109141 acccatcata agcatattag ggtcataatt tgattccaat actactaatt tagatttata
   109201 tagatgtttt tttatatttt gagttataca tcctatatca gtagctatag acattttttc
   109261 atcactctct gtataaaaat tatatccaac tgggtcagac gcatcatgtt ctattgaaaa
   109321 aggtcttact atgatatcac ctaatgagta ggttttatca ttttcaaata ctttcatatt
   109381 tttatctttg atgtcaccta atttgtcctt catagaacac catgttttta tattagcaaa
   109441 tactggtata tcaaactttc ttgataatat acctgctcct tttatatggt caacatgctc
   109501 atgtgttata aatattcctt ttaatttatc tgcatctaca ccaatgtctt taagacctgt
   109561 agttattctc ttgccactta atcctgcatc tactagtata ttagtatttt tataccctat
   109621 atagtggcaa ttaccactac taccactccc tactgaacaa tactttagca ttccttcacc
   109681 tctttttctg ccttataaat tatattatac caaaaaaaca gagtattaaa taaaatttaa
   109741 tactctgcac aaaatttact tacattcact atttacttac attcacttat aatcttattt
   109801 atatctacac ctttactatt ccatagttcc acaaaagctc ttccattagc atttttatgc
   109861 ttatatttat tatagtactc atttaaagtc tcaaagaata ctttatctcc aacttctttt
   109921 cttatttcat taaatgctat tgcgcctttt gtataaacat tcaagctgta ttcagtagaa
   109981 tttttatact catttgctgg cttaaatata ttttcactca aataactttt tgtctgtatc
   110041 tccatagttt ttataagctt gtttgccata tctttaccat acttttgttc aaaataaact
   110101 attgtagaat attcagtaag tgcttcatct aaccagggtt cacttatttc atcatttcca
   110161 acagcagaat accaccattg atgtgctgtc tcatgggcaa taacatattc tagtaaaaat
   110221 tcattttttt cattatataa actttggtct atcataacaa gcatagggta ttccatcccc
   110281 cctataaaaa agtcacttgc tacaacagaa aattctttgt aaggatactt tccaaataat
   110341 tcactaaata tatttattga atcttttgcc acttcagttg cttttttaga aagcttttta
   110401 tttaaattat atgtattgat agctactccc tttgaatcta ctttgtttac atcaaattta
   110461 ctacttagta taaatgcaaa atctctaacg ttttcagctt ctatttcata tagcattttc
   110521 ttattatcat gtttatcatc aataagtttt cctgtatgag caattttata tttatttgga
   110581 atcaatagtt tcacatgaaa atcgctagtc tcactataaa atgggtcgcc aatagtttca
   110641 taactcttta aattccatcc cctttcatca tttacacaag ctataggaaa ccaattagta
   110701 acatttatag tattttctcc atatccaaat cttccaattg aatttggtat ttttacgtta
   110761 tattttatat ctaatgacat tctttcattt ggttttaact ctttccctaa ttctatttct
   110821 aatatgtcat ttttgtctcc tttaatttta tactccattt tactattatt atttaatata
   110881 ttctttatat ctatatatcc ttcgttaaat ccattaggat aagcccttgt catttcactt
   110941 ttttcaaaag gagcaaaatc tttcttggaa aaagcattcg gatatatatg gaaatatatt
   111001 ttatctatgt ttgattttgt attatttatg tagtcaacat tctgattgca cattaacctc
   111061 ttagtctcat catcaaatat aacatccata ttatactgat ttatttttga attagttttt
   111121 tctttgtatg tttctaaact gtcatccttt tctataaagc aacctattat taataccata
   111181 aatagaatcg ctactgataa tgttcttctt actttttggt tgaattttat aaccaaaata
   111241 tctcctcctt ttcaaaatga atacttttag aaaatattta catgctaatc ttgtgacctt
   111301 ttatttgttt acagacaaat ataatataaa aaatgatata atttaatctg aggtgataaa
   111361 atgtttttta aagaaagcaa tgaaatagat ttaggtgaaa tcactattcc caatatcttt
   111421 atagatatat ttatgccaat ggcggacggg ttatacgtaa aagtttatct tttaggatat
   111481 agacaagcat gtgatattac ttctaatcct aagttcgaca ataattcaat agccaaaaac
   111541 ctaaatatac cattgtctga tgtgttatct gcttggaaat tctgggaaga aaagaagatt
   111601 ataaaaatac atgacaatga agaatatgat aattttaatt attcaataga atttttagat
   111661 ttaaaaaatt tctatattga gaatatatta agcaataatt catctataaa atctaataca
   111721 gataaagttg tatctacttc tgaaaatcca agtattagaa aaatgtttaa ttctataaat
   111781 aaaatagttg ggcgatatct cgacccaagt gaaaagatga gtattatgga tataatgaat
   111841 aaatacaata tgagccccga tatgatactt tgcgcatatg aatacgtcaa agataaaact
   111901 ggtacatcaa agccagttaa atacattgaa ggcattatta gaaattggta tgattcaaat
   111961 ttatatacgc caaaagatgt tgaagaaagc tttttggtaa gaagtgaacg atatatttta
   112021 tataaaacga ttttcaatga attgggattt tcaagacaac catcaaaatc agaaaaagaa
   112081 cttatggaca cctggtttga taaatttaat atggatatag atttgataat aaatgcatgt
   112141 tctaagtcta agaatatttc aaacccaagt atatcttata taaatggtat aattaaaaat
   112201 tggaatgaaa aaaatataaa aaatttaaat gatttaaagc aaaaagagga agaacgtata
   112261 gttaaggaga atattaataa gaagcagatt aatactactc aaaacaacaa tacttacaaa
   112321 aaaactaagt ttcataattt caacgaaaca ttcactcagt atacctctga tgagctcgat
   112381 gagattatta aaaaaagtca aaaagaaaag tttaagtagg tgattaaatg aatgaggata
   112441 aaataagaaa aatacttgct aaatatgcta agagaagaga tgataatgaa ctcttattag
   112501 aacatagaaa aaatgaggta tataatagaa tccctgagat aaaatctata gatgatgaaa
   112561 tttctaaaat aggtctcagt ttagctaaga tagtactttt aaatcctaag tctaaagatg
   112621 aaattgtaaa gaagactaaa gagaatatag aatctttaaa agtaaagaaa gaaagacttt
   112681 tagctgaaag taacatacct cttgattact tggaaataaa gtttcaatgt atttcttgta
   112741 aagataaagg atttttacct aatggagaaa aatgttcttg cctcaaacaa gaaattgtaa
   112801 atgaagctta taaaatgtct aatttagata ggattttaag tcaggaaaat ttttcgaatt
   112861 ttaacttgaa tatattttct cctaagaaag gctctgatgg tgaaatatct cctagagaaa
   112921 atatgctaaa taatttaagt atctgcgaaa attttgttca tgattttaag aaggataata
   112981 gtgaaaatct actgttttat ggttctactg gactaggaaa gacctatatg tgcaattgta
   113041 ttgcaaagga attgttagat aaaggcaatg ttgtaatcta tcaaacttct tttagaattt
   113101 tagatattct tgaagattat aaatttagaa gagacacaaa taatcaaata agtgaagata
   113161 attataaaaa cttgtttgat tgtgatttat taataataga tgaccttgga actgaactta
   113221 ataattcttt tactagtgga gaaatcttca atattgtaaa tacaagactt gttgctggta
   113281 aaaaaatcat tatttcaacc aacttaacac catctcaaat aggaaatact tacactcaaa
   113341 gaactctctc tagaatatta gataagttta ggattttaga atttactgga gatgatttga
   113401 gatgggaaag atttaaataa aatagccctt aaaaaacatt tttttatttt taaatagaga
   113461 ggtaagagca aacttgcttc tctgtttaaa acttatatca cataaattaa aacatacttt
   113521 ttatttttct atttacatat ctaatgtacc ttaatctaac aaatcattta cattcttagt
   113581 agtctatatt tattgatact ataaattaaa tttgctatat tacataatat tatgctagaa
   113641 tgattctaaa ttttatattt aaaactatca cattgcaagt aattcaaaat tttgttgtat
   113701 gtttaatttc atttttaata caataaaaat gaaattaaaa aaagatactt aaaagtatcc
   113761 tgtaacatag aaaattatat taatttgaat ttatgtactt tgtggagctg gtgataggaa
   113821 tcgaacctac aacctgctga ttacaagtca gctgctctac cgttgagcca caccagcata
   113881 taatctagta tttatctcta attcaaaatt tggtgggact aacagggctc gaacctgtga
   113941 ccccctgctt gtaaggcagg tgctctccca gctgagctat agtcccatac tggtgactcg
   114001 taggggaatt gaacccctgt taccgccgtg aaagggcggt gtcttaacct cttgaccaac
   114061 gagccatatt ttggtgatct atccgcgact cgaacgcggg acaccctgat taaaagtcag
   114121 gtgctctacc gactgagcta atagaccaca ttttttcgac ttttttcgtc gtttctttca
   114181 ctcacaagtt atattatagc gtctatataa tttttagtca atagtttttt ttactttttt
   114241 tagaatataa ttaaaatcat ctttagccat ttattttcaa caaaattctt tttaaaaaac
   114301 ctatatgtat ctacataaat tcaactttaa tttcagttag aatatgtata agtagcttta
   114361 acttaataaa aaatcaatgt aagtcaaata taaaagagca tctctaataa ctataaacat
   114421 tatcttgaga tactcttctt caactatttt aaattattta attgataaaa tattaagcaa
   114481 atatatttct tcttattata gtttgagctc tatttggacc aacagaaacc atatctacac
   114541 ttactccaac tagttcttct atttttgcta catatttctt tgcattttct ggaaggtcat
   114601 caaagttatc tatttgagtt atatcttcat tccatccatc taattcttca tatacaggtt
   114661 cacattttgc taaatcatct aatgaagctg ggaaatccgt tattatctta tcgcccattt
   114721 tataagacgt acaaactttt atcttatcaa atccagttaa tacatcaagt aacataaatg
   114781 aaatactagt caatccatta actctagctg catacttaac tataactgca tcaaaccacc
   114841 cacatcttct tggtctacca gtagttaccc caaattcatg tccttgttct cttatcttat
   114901 ctccagtttc atttatttgc tctgtaacaa acggtccttc tccaactctt gtagtatatg
   114961 cttttactat accaacaacg tcttttatca tatttggccc tatacctgca ccaattgcaa
   115021 atccaccaga tgttggatga gaagatgtaa caaatggata agttcctaaa tctaaatcta
   115081 ataaagtccc ttgtgctcct tcaaacaata cttttttacc tgctcttact gcatcatata
   115141 caataacaga cgtatctgcc acatattttc ttatttgctc tgcatatcct agatattcgt
   115201 tatatatagt ttcaaaatca aataattctt cttttccata tatattttta actatttcat
   115261 ttttagcatc tatttgagct tttaatttta tagcaaattt atctttatcc attaagtcac
   115321 atattctaat accagatctc tctgttttat ccatataaca aggtccaata cctttttttg
   115381 ttgtacctat ctttaaatcg cctctggctt cttctgacaa tgcatctagt tctttatgat
   115441 atgggaatat gacatgtgct ctatcactta tttttatatt ttctgtactt atattatccg
   115501 ttttaaacat ttccaattct tctaaaaatc ctttagggtc aaacactatt ccatttccga
   115561 ttatattcac tgtatttgga tttaaaactc cagatggaat tagatgtaat gcgtattttt
   115621 taccttctac aactaatgta tgtcctgcat tatttccacc ttgccctctt actactacat
   115681 ctgcttgagt agcaagataa tctataactt tacctttacc ttcatctccc cattgagaac
   115741 caacaattgc aactgttttc atgtaattca cctctatatt ttatatactc tcgaacactt
   115801 tacttactta ttctatcaaa cattcgtatt tttttcaact tttttagtat tctccaatat
   115861 ttaacatata ttcttctatt tttgaaaact cttctttctc tattatttct ttttcatatt
   115921 ttataacttt ttccataaat ttatccacat ctaaaagttt ttctaattta catatgttaa
   115981 ttatatttcc aaagtttgta ttagtcatgt ttatatgata ctgattatcc acattattag
   116041 cataaacaac aatagattct cttaaattat tgtcaattac tctaaataag tttatttcat
   116101 caagtacttt aattatattg ggatatatat attttaagct tattttttcc atattattcc
   116161 tcctaataat taatatttat acacagataa agcaagccaa aagcttgctt tatctactta
   116221 ttcacactta tcaacaggcc atctgtggat agtgtggata gttttttagc taaatttcaa
   116281 tgtttggaca tatttagtga catgtatcca catttttcct gtagaaagaa aggacgttct
   116341 gtggatattc gttagattat aggtctctca acttatcccc aaatctttga acttcaccaa
   116401 gccaaacaag ttccacagaa ccagtttcac cgtgtctatt ttttgctatt attacttctc
   116461 ctatattttt actctcagaa tcagcatgat aatattcgtc cctgtataag aacataacta
   116521 tatctgcatc ctgttctatt gctccagact ctcttaaatc agataacata ggtctatggt
   116581 ctgctctttg ttctggtgca cgtgataact gagatagtgc tactacagga cagtttaatt
   116641 cttttgctaa tatttttagt gaccttgata tcttagatat ctcttgttgt ctgctttcat
   116701 tattaccttc accttccata agttgaagat aatcaataag cactaaatct agtccttttt
   116761 ctatttttaa ctttctacac tttgacctta gttctgatat ttttatacca ggagtatcat
   116821 ctatgtgtat tttggcatct gataatactg ccatagcatc tataattcta ggccaatcat
   116881 tatcattaag tgttccagtc tttatttttt ttaattctac actagattgt gaagataaca
   116941 tacgttgtac taattgttcc ttagacatct ctaaactaaa tacagctaca gaggcatcac
   117001 cttttaaggc tgcattttga accaagttta aagaaaaggc agttttaccc attgctggtc
   117061 tagctgcaat taatattaaa tcagtccttt gaagaccatt tatttttttg tttaaatctt
   117121 taaaaccagt agttatacca gtgacatcac tcttgttagt gtataatttt tctatcatat
   117181 cataggcatc catcaaaact aagtttatag atttaaaatc atcactagtt ttctcctgtg
   117241 atatatcaaa tatactcttt tcagcttgtt ctaaaacatc ttcaatctta gttgctccac
   117301 tatatcctag atttattatt tcattagaag cttttataag ctttctaagt acagactttt
   117361 cttttactat atcagcatag tattttacat ttgaagtcgt cggtactata gtagaaagac
   117421 ttgtaatata actgattcct ccaatatcat taagatgccc ttgttttctt agttcttctg
   117481 ttaatgttat caagtctata ggctcacctt tattacttaa agttatcata cattcatata
   117541 ttattttgtg agcctcttta tagaaatcat caggctttat agtttctgta accgttatta
   117601 tagcatcttt atctagaagt atagaaccca atattgattg ttctgattct acactatgag
   117661 gaggaattct cgtcatatct tccatcttaa tcacctctag ttattactgt ttttctttta
   117721 catccactct tattttagta gttacttttt gatgtatttt tatttctacg aaagttgaac
   117781 ctaaagatct tattggttca tctaataata tttttctttt atctacatct atgtcttttt
   117841 gtttctttaa ttgctcagca atttctttag aagttattga accaaataat cttccacctt
   117901 ctcctgcttt tgaatatatt tctatattaa tttcttccat ttgcttacct aataaaactg
   117961 cttcttcata ctctttttgt gcttttattt ctttagattt attcttttca tttaattctt
   118021 ttattgctac actatctgct tgcacagcca tctttttagg aaataagaaa tttcttgcat
   118081 atccatcact tacttctttc atttctccct ttttaccagt tccttttacg tcttttaata
   118141 atataacttt catctattct tcctcctcca aatactcctc tattatttta tttaccatct
   118201 tataagcttc ttttagagaa acatttttta actgtgctcc agctatatct atgtgtcccc
   118261 cgcctcctaa tttttccata agtacatgta catttatttg tcctaaagac ctcgcactta
   118321 taaatatagt atcatctttt tcacctaata caaaggaagc ttctacttct ttgatattta
   118381 ataactcatc agcagtttga gctattataa catttatact atctatctca gtacttgaat
   118441 atgctaaaca tattctatta ttaattattt tagtactttg aattatttca gcttttatta
   118501 tgaaatcttt tacatcagaa ttgaagaatt tctttacctc tatagtatct gctccaactt
   118561 ttctaaggta agaagcagct tcaaaagttc taacacctgt tttgaatgca aagtttttag
   118621 tatctagact tatacctgct aaaagccctt cagctgtaag tttatttatt gttacatctt
   118681 catccatata ctgaactaac tctgtaacca tttcacacgt tgaggataca tatatctcat
   118741 ggaataaaag cactgcatca tttataaact ctacacctct tctatgatgg tctataacta
   118801 ctaccttctc tgatagcttt aacagttctt cacattcagt ataatttggt ctatgagtat
   118861 caactactac aactaatgta tttttagtgc agttgtcaat agcttcctct tttccaataa
   118921 acaacttttt atagtaatta ttttcattta ttttatttat aaatatttct atagattcat
   118981 ttacagattg taaaactatg tttgcagttt tgttacagga tttacatata tcataaacac
   119041 caactgctgc tcccatagca tccatatcag gatatttatg tcccattata taaacttggt
   119101 cactttgttg tataacctct cttaaagcat gacctattaa tctggatttt actttggttt
   119161 tcttttctac agctttagat tttcctccat aaaacacaaa tttatctttt gtttttacaa
   119221 cagcctggtc accacctcta ccaagtgcta aatcgagagc acccgtagca agttttaggt
   119281 tctcatttaa tgtatctcca tctataccaa ttcctatact tatagtaaca ggaagattat
   119341 ttccataatc aatatgtctt attgtatcta aaatagaaaa cttctcagct tccaattttt
   119401 ttaactcttt tttatgcatt accaagaaga atttgtcttt tgaagttctt ctcaatgcac
   119461 catttgaatt taattctaaa gcagaaagta ttttctctac ttcaacatta attaaagctc
   119521 tcttatcttc tgctgcactt tttaatactt catcatatcc atctacttgt attagcatca
   119581 ttgcattttt ttcatcatca taattttgtt ttacttttaa atattcagtc ttgtctatcc
   119641 agtataatat catcaaatat ttaggatttt tttcttgatc attttttata acattataaa
   119701 ttattgtata ttctttttct ttatagttta tttctgtgta catctcttta ttttcattta
   119761 atacttttct taaattaaga tttttaacta tatcctctat atttttatca agtaaatctt
   119821 tttgaccaat catatcataa aactttccat tataccagga tatatttcca tcaaattcta
   119881 aaatacataa tggtattgga agatttatta tggctttttt agttgtttca tctatatcta
   119941 aagataaatt ttgaatatac tctgtccatt catgacgtct aatattagta gttctccaat
   120001 tgtgaaaaac catatataca aaaatacaga aaaataaaca ccctacatac aagttgtaat
   120061 aaagcaaaat tatactagaa ataccaataa caattatata taaatttatt tctggcatat
   120121 ttaatttaaa ggtttgttta ttactcattt ctatcctcct aagtggattt atagcttctt
   120181 acctttctaa agtcaattat actatctacc ataccaacaa aagatattcc cataaatcca
   120241 aataaacata aaattatccc tgaaaaaaac ataattttat ttggtccctg tcttatccat
   120301 ttctttaaga aataaatgca aactgctata ccttgaatta caaacattaa attaaaaact
   120361 agctgtaaat tagtcattat taattctgta tataattttg aaccaataat ttgaataaat
   120421 aagactaata aataaagtaa gaaagttgtg agtatagcat ttcccggtaa ataaaaatca
   120481 gcaaacttag gaaatcttat attcatcttt gtaatccttt ttataaaaaa tacactcaaa
   120541 taatatgtga caaacgctga taacaaccct tgtaaaaata acatcattgg tagcatattt
   120601 gtaaaataac ttacaatctc atctggcttc attttatcaa acactttaag ttcagttgca
   120661 gaaaaactat ttttttgaat atttacaatt tctgatatca tcttagaaac ttcatctaat
   120721 agattcacat ttaaaaatgt ctttaataca aaaaaatata caagcattga aagtacaaat
   120781 attatggttc caccatatat cggttcgaat ttattactgt cctcttgttc aaagcttctc
   120841 tttagcatct ttcctattac tatacctggt aaagaataca ttatacatat atttaatgca
   120901 taagaaatgt ctgcaaatag aatcagtaca caaaatgtaa ccaaaataga tataagagaa
   120961 tactttctat cagtaatagc acctataatt acatatggaa cagctgctaa catactaaat
   121021 attcctagca ttggaatata ggctattact aaagcgatta ttatagctaa aactattata
   121081 gacattgcct tagatagtct aattttatta ttcaatttaa tatcactccc tattatccat
   121141 atgttttttt aaattagata aatctccata ccatctttca acgctatggt cctcatctat
   121201 accaattttt attttttcct tgactttata atccacatct ctaaaactaa ttcctaatct
   121261 ctttgctaag agatatgtta tcattattat atttgctaaa gtatcttgaa ttgcttcatc
   121321 taatggtttt acccctttaa acaataaatt aaacaaatca cttacactca ttaatatttc
   121381 tgttttcatc cattctatta tctttatgtt tctcgttatc tcagaacctt tatctatttt
   121441 cacgtttaca accctcctta atatataata ttatatcata aataataata tatttaagta
   121501 tataaacaaa aaaacgagct ttatagctcg cctcatttag atatataaat acatataata
   121561 aaaaatgagc acaaggctca tttttttagt ctaatgtata tggtaaaagt gctatatttc
   121621 tcgctctttt tatagcaact gttaattctc tttgatgctt agcacaagtt ccagatattc
   121681 ttcttggtaa tatctttcct ctttcagtta tatacttttg taatctttga gtacttttgt
   121741 aatctatttt agcgtttttg tcagcacaaa attgacaaac tctttttttc ttacgtcttt
   121801 ttttattcat catgactttt ttccctcctt tttaaaatgg tatatcgtca tcatctatag
   121861 cttggaaacc ttgtgggtct aaaccttgag gttcaaagct tggctcaaaa gctggagcac
   121921 tctctctata tgaattttcc gatttattct tactatccaa agcttgtact gatctagtac
   121981 ttacttttgt aaaagttctc ttttcacctg attgtgtctg ataattgtct actcttatag
   122041 atccttgaag tgctactaat ctacctttag ttatgtagtt agcacaaaat tcagcagatt
   122101 tacccattac ttcaacaggt ataaaatcag tttctttaga tccatctttt tttacatagt
   122161 ctctatcaat ggctattgta aaggatgcca ctggtgttcc tgtacctggg atgtatctta
   122221 attcagggtc tctagtcaac cttcccacta atacaacttg attcataaaa acaccaccta
   122281 ttttttataa taaaaccagt tattaagcaa caactatcat gtgtcttatt acgttttcat
   122341 ttatctttaa gtttctgtct atctctttag gaacgtctac tgctgatttg aagttaacta
   122401 atacatagaa accttctgta aacttagcta ttggataagc taatttttta gttccccaag
   122461 tatcaacttt aactatttct ccgtcagttg caacaacttc cttaactttg tttagtatag
   122521 cctctcttac ttcttcatca gagtttggct ttaccacata aactaattca taatttctca
   122581 ctataattca cctccctttg gacttaacgg ctctacactc ttagagcaga gaaatgagac
   122641 taaaatctca tacctacaca ttttatcatt tattcttatt tctgtcaatt taaattttgg
   122701 acaaagttta gtataaggtg aattatatac ttttcaaaca aacaagggat ggcaacaacc
   122761 atcccttgta ttatatataa gttattattt ttaattaagc ttctacaccc atagcttctt
   122821 ttaatacagc tgctatattt tttatacctt ctattatttt ttcttctggc atatttgaat
   122881 agttaagtct gaaagtattt tctctaccac cattagggaa gaatcctcct ccagcaacat
   122941 aagcaacatt cttatctaaa cattttggca ttaattcttt agcatttaaa ttacttggaa
   123001 gctctaccca tgtaaataat ccaccttctg gatgagtaaa tactaatcct tctgggaact
   123061 cttcttccat agtcttaagc attacatctc tacgtttaac ataaactgct tttattttgt
   123121 caacatgtgc atctaggtca tacatatcca taaatttgct tacttccatt tgagatatag
   123181 ttgatgcttg taagtctgca ccttgttttg caaagttaaa cttagataaa atttctggag
   123241 aagcacaagt ccatcctaat ctgtatcctg ggcagaatat tttagagaaa gttcctaaga
   123301 atattactaa tccttttgta tccattgatt ttaaagatgg taaagtctct ccttcaaatc
   123361 ttaaatctcc atatggatta tcttctatta ctggtatttc aaatttattt actatttcca
   123421 tgaatttttt acgtctttca agtggccaag ttcttcctgt tggattttgg aagtcaggta
   123481 ttacataaat catttttatt ctatcagttg tttctagtat cttttctaat tcttccatta
   123541 tcattccatc agaatctgtt ggaacatcta tgaatttagg ttgataagat ttaaatgcgt
   123601 ttatagctcc tatgtaagat ggactttcac ataaaattac atcaccctca tcaataaata
   123661 cttttcctgc aaaatctaga ccttgttgag aaccacttgt aactaatata tcatctttgt
   123721 ttacattagt tttgttttta tcattcattc tagctgctat tttttctctt aatggttcat
   123781 atccttctgt tgtagtatat tgcatagctg atcttccatt ttcttcaagc actgcaactg
   123841 atactttttt catttcctca actggaaata actctggagc cggcattcca ccagcaaaag
   123901 atattatttg tggttgttga gtaagtttta aaagctcacg tatttctgat ccttgtaatc
   123961 cttgcattct ttttgcatat ttaactgcca taattaaagc acccccatga aaatgttttc
   124021 ttcaattctt attataccaa aattttggat attaatatac ggtatttgac attttttaag
   124081 tgttaaattt ttatcacttt tttattagct tttttactct cttttctaag gtctctctat
   124141 caagcattat tagccttgaa catttagtac attttatctt tatatccatt cccgttctta
   124201 tgatttcaaa ctctttacac ccacatgcat gttgcttttt taattcaaca atatcaccta
   124261 tttttaaatc cattggcata aataattagc ctcctaatct aacttctcta cttcttttga
   124321 accattttct aatttactta tacaataaat tccttttata tctacattat tttcaaccaa
   124381 aatagttttt atcttttcca tatcttcaaa agaaaattta attgatattc cacaacttgc
   124441 tgttatttct cttggtgttg gaagagccat tacttttaga ctattttcac caaataactt
   124501 ttctgatctt atcgcatgat gtgtcgaatt aaatgacact atatacattt gattcattac
   124561 ttaatccttt ctgactatct atttgagtta atctttattg ttagttttat attattaaac
   124621 atacatacat tatatagaaa tggtatttga tgcattcttt aatgtctcaa ctatagtata
   124681 catatttgta actgtaccta cttgtaattt gtcttttaaa ttataataat ctaaacaagt
   124741 accacaagat aaaacttcta cacccatatt ctcaagtatt tttagatttt ctatggtttc
   124801 ttcattttca gcacttaatt ttactcctcc attaactaaa agtacatact taggataagg
   124861 tttagattct gttaatgtat atataaatcc ttttattaac acttttccta attcgtcatt
   124921 tccaagtccc atcttatctg aagatataaa tatacatgta ttgtctaatt cactttcttt
   124981 attatctaca acattttgtt tatctagtat atttttacct tttctaattt ctatagatat
   125041 aaaattctct ttttcgtcaa caatatttgc ttcacaactt aaagatttag caagttttaa
   125101 tatattctcc ttagctgttt cattatcaac tattgtaact acaacacctt cttctaggtt
   125161 atccaattct ctttttgtat ttataactgg tttaggacaa gcaagccctc tcgcatctat
   125221 ttttatactc attgtctgat tcatctcctt aaaaatattc atacaattta tattttatca
   125281 tagatattat cttgcttgtt atagattgtt tctataccct tataggttta tttaccctac
   125341 attatttcta aatttttgta cataaataca cctttttgat aatattctaa ctctttttct
   125401 tttgatatat ttgaatataa ttgacctaag tctatatata aattggccaa tattctattg
   125461 ttgcctaaat ctgatactat ttttatgcat ttaatcagat attcaattgc aagagttact
   125521 tcattctgat ttttatacat attagcatag aatctcaatg ctttatattc attgaattta
   125581 tttttatttt ttattgatga agctaaggct atcttacaat attttctagc taaatcataa
   125641 tcttctttat ctatatatgc ttctattatc ttaaataatc ctgacatcat gtattcatct
   125701 tcatcatttt tctttatgtc atataccttt tgtgaatatt caagtactct atctgtttca
   125761 cctatttttc tgtaaacatc acaaattgtt aaatacacat ttgctaatcc agttttatta
   125821 tcctcactct caagtatttt tagtgctttt ttaaagtaat ctcttgattc ttcatatttt
   125881 ccaatctcaa gcatattatt tgcttttaac accaaaatat cgacatcttc ttttctatca
   125941 tttctattat ctatttcatt tatcttttct atgtacttca atgacatatt tggattatct
   126001 agttttatgt aacaatatgc catcttacta tatagttcct tgtgtatgtt aacatcctca
   126061 aatttactct ctgacaaaat ttcctctgca aaattaaagt ggcttatagc acctttataa
   126121 aagtcttcct gcatatatat tttccctatg tttaaataac acttaagtat attttcacta
   126181 tcactatttt ttataaagaa gtacaatgcc ttttcaaagt tttctatagc atcattataa
   126241 ttagattttt tcaaattaat attagccatt aaaaaattac atctgccata gttctccatt
   126301 aaatcgtatc tcttacatat atctaaaact tcttttattt ggtcctcagc cttgtttaat
   126361 tcattttctt ttatataaat ttcgctctgt agtattaaat tatcagttat cttttttgat
   126421 tgcatttcct tggtctctaa taagtattct acacttacat ctagcttatc gcctagatat
   126481 tccaacagtt cataactagt atgagattta tctctctcta tatggcttat ttgtgctgct
   126541 gttatcctat ctccagctaa ttctttcaat gtcatgtttt tttcttttct taacttttta
   126601 atcttttctc ctaagctcaa aatttccata ctattcccac cttttgaaga cattttttta
   126661 taatataatt ataacttata tttattttaa aaacactact tttattttac aatattttca
   126721 ctgtacatta aatgatttcc cataaaaatg actaaaattt agtttatttt gagttttatt
   126781 aatttaaata aatcattttt taaatttgtt actattttgt attcatatat ttgctcataa
   126841 cgactataat tatatataag aatagttttt aagagaggag aaatttttat gaaaaataag
   126901 aaaataatgt tagtgttaag tatattatct atatctatat tcgcagttgg ttgtactaat
   126961 gctcaaaatg gaagtgattc atctaaaaaa gaaactaaga gcaatacaaa tgttgagcaa
   127021 ccaaaagaag aaaacaatac tgaaaaagag gttcctaata acaaagctaa acctactcca
   127081 aaagaagaaa ctaaagctca atcagctact atttactctt ttgatgtaga taagacagat
   127141 ttaattgaaa ataaagttga tttaaataaa attgatgaga acactttatt tgaagaactt
   127201 caaaaactta aagttgttcc agaatctgca aaattaaatt catttactac aaaagacatt
   127261 gatggtgtaa aaactggtat attagatgtt agctctgact ttacaaagtc aaacttaggt
   127321 agtgatgcag aaactttaat gcttgattca gttgctcgta cttacataaa aaatatgaat
   127381 gttgaacaaa taaaaattac tgttgatggt tctaattacg aaagtggtca tatagttctt
   127441 gaagaaggag attacttaaa gtaatttctt gaaactatta tcaaatagat tagaggttct
   127501 taggaacccc ttttcttttt tgtacaaaaa aggagatgat tcaaattttt attttgaaat
   127561 atcccctttt tttatttcta tattattaaa tctcatgcta tttatttttt gaaatttttt
   127621 tcaaagcttc cactgcttta tctatctcat cttttgtgtt gaaatatcct atactgaacc
   127681 ttactgcacc ttgttttaaa gtacctaaag tggtatgtgc tagtggtgaa caatgtattc
   127741 ctgatctagt cgctatatta taatcactat ctaataagaa agtaacctct ccagaatcca
   127801 tatctcctat atttagagct attactgatg ctcttttttt actgtccttt ggtccatata
   127861 tctttatatc tggtacttcc tctaatttgt ctatcatata ttgacataat tcttcttcat
   127921 gttgtcttat attgttgatt cctctttcaa atataaatag tataccttgg ttaagacctg
   127981 ctatacctgg agtattatga gttcctgatt catatttatc tgggaataac tctggttgaa
   128041 ctatttcttc tgatttacta cctgttccac cttcttttaa tatatttaag ttcaaccctt
   128101 ctcttacata taatatacct gttccttgag gtccaaataa gcatttatga cctggcattg
   128161 ccaacatatc tatattacat tcatttacgt ctatatcata aacacctgct gtttgtgatg
   128221 catctactaa aaatagtata ttatgttttt tagctatttc tccaactttt tttatatcta
   128281 ttaaagttcc acatacatta gacgcatgtg ttgttacaat caatttagta ttattcttta
   128341 ttgatttttc taaatcttca taatctaaaa atccctcata atcgcatttt actacagtat
   128401 tttcaatacc ccttttttcc aatgctttta taggtcttat tactgaatta tgctccatag
   128461 acgttgttat tacatggtct ccttcttgta atacaccttt tatcgctaaa tttaaagaat
   128521 ctgttgcatt agatgtaaat actatattca taggattact tacattgaac aacttagcta
   128581 tattctctct tgtatcatat atctccctag cagctctcat agcaagttta tggcctgctc
   128641 tacctggatt tgcacaataa tttttcatac aatctaaaac agcattatac actctttctg
   128701 gttttggata tgtagttgca gcattatcta aataaatcat aacaatcttc ctctctgttt
   128761 tatatttttg ttctattcaa gaagcattga tacaatacta tttaaatcat catcattata
   128821 gtattctatc tctattttac cttttttctt tcctttagaa atattcacct ttgttccaaa
   128881 tatatttcta agtttatctt caacatctaa aataaataca tccttaggtt tagatttttt
   128941 aggttcttct tgtttatttt cagatatttt tttagctata ttttcgactt ctcttacaga
   129001 aagttcttct tcttctattt ttttcgctat ttgaagttgc aaatctttat ctgcaattct
   129061 caataaagcc ttaccatggc ctgctgtaat tctaccactg tctatcattt ctataacatc
   129121 ttgtccaaga tttaaaagtc ttagtgtatt agttatatga ggtctactct tcccaacagc
   129181 ttctgatatt tcttcctgag ttacattgta atgctctatt aaactcttat atgctagagc
   129241 ctcttctatt gaatttaaat cttccctctg taagttttca attaaggcta tctccattat
   129301 atctttcata tctatatctt taattatagc aggtatttga tttttatttg caagttttga
   129361 tgctctaaat cttctttctc cagctattat catatattta ttattttcat ccattttaac
   129421 cactattggc tgtaaaacac cataattttt tatagaatcc gacaatactt ttatcttttc
   129481 ttcatcaaat tgctttctag gttgaacttc gtttggatat attttgtcta tatctatgtt
   129541 gactatttct ttttctgaag tttctccttt aatttctggt atcaatgcac taagacctct
   129601 acctaatcta ttacttcttt tagacttatt ctccatacta ccattcctcc tcttctaaat
   129661 ctataaattc ttctgctagt tccaaataag ctacagaccc tctacatctt ttatcataat
   129721 aaattacagg ttttccatga cttggagctt ctgcaagtct tacatttctt ggaattaaag
   129781 ttgtatatac actaccttta aagtatttct taacttcttc aactacttgt attgataaat
   129841 tagctcttcc atcaaacata cttaaaacaa caccttgaat ttctatatca gcatttaatc
   129901 ttgattttac taattttata gtctccatta attgactaac accttctaaa gcataatatt
   129961 cacattgtat tggaattaaa acactatcta cagcagttaa acaatttatt gtaagcatcc
   130021 ccagtgaggg tggacaatct aaaaatatat aatcatattc atctattacc gcttttatgg
   130081 aattttttaa aatatactct ctattagttt tagatgtaag ctctatctct gcacctgata
   130141 gttcagtagc tgatggaact acatctacat tctcaaattc agtacttatt attgcttctt
   130201 taatatgtaa cccatctaac ataatttcat agattgtatt ttctacttcg tttttattaa
   130261 taccatatcc actagttgta tttccttgtg ggtctaaatc taatactaat attttctttc
   130321 ccaaagttcc taagctagca cttaaattta catttgttgt agttttcccg actccaccct
   130381 tttgattgaa tacagctata actttgccca tgatgttccc ccctttaaga attaaattaa
   130441 ttttaaatgt tgaataggtg ttttttaagt ataaataatg tctataaatc aatttatatt
   130501 acaaggctta tattacaaaa aaagattact ggtaagcagt aatctctatt ttttagggat
   130561 ttttacaaca acttccatat aatctccctt atctatttca ttatacttag catcaattcc
   130621 tgtatttgat atagcatcaa aggcctgctt tatagtattt atgtaaattc ttatactcat
   130681 agcacccttt atattctgtt ttttatcagg ctcttcttga actttagttt cttctaatac
   130741 atcttgtatc aatttttctg tttttttaac agtcaattca ttttttatga ctttgtctaa
   130801 cacactttgc attaaatctt cacttggtag tttaagaaat gctctagcat gtctttctgt
   130861 taaattattc tctattagct tcatttttat atcgtttgga agctttaata ttctaagctt
   130921 atttgctaca gtagattgat ttttgcccaa tttttctgct aattgctgtt gagtaaaagc
   130981 atgttctttt attaagtttt cataaccaat tgcttcttca atgaaattta agtcttctcg
   131041 ttgcaaattt tctaataacg ctagaacagc agaagattca tcgttcatat tatttataat
   131101 tgctggtatg gttttaagct ctgctaattt agctgctctt aatcttcttt ctcctgcaat
   131161 tagttcatat ttgccatctt ttgctctaac tgttataggt tgaattatac catatacctt
   131221 tatagaattg ctcaattcct ccaatgaaac ttgtgaaaat atttttcttg gttgatatgg
   131281 atttggaact acatcttcta taggtatctc cataactctt ttatcttcca taacatacct
   131341 ctcttatttt agatataaat tatttttgtt ctctatatgt acatacaaat ttatttctgc
   131401 atctacttta ataattcctt tatttttgtt tttttacagt aagcttaatt atttcctgag
   131461 aaataattaa gcttaccaat aataaatttt tcattactta ataggatttt tggctggttt
   131521 accagctttt ctagggtact taactggtgt ttccatcact tttttaaaaa ctaatatatt
   131581 atgatttaaa tctacctctg gtaactctac atctattttt tcaatatact ccaatcctaa
   131641 aacatcaata gccttttgtg attcttctag ctctaaatta gcattcggac cttttaagca
   131701 aataaaatac cctccaactt ttacaaatgg tacacaaaat tccataagaa tcggtaatcc
   131761 agcaacagct cttgccgtag caacatcata tttttcccta tagtcttcat ttttaccaaa
   131821 atcttcagct cttccatgta taaatgtaat attatctaac tctagtactc tactaacttc
   131881 ctctaaaaag tttattcttt tatttaacga atctaacaaa gtaagttcta agctatctaa
   131941 acatattttc aatggtattc caggaaaacc agcacctgta ccaacatcta ttatagacat
   132001 cccatttttt atatatccat tttttacagc tgaaatagag tctaaaaaat gttttatata
   132061 cacttctttt tcatcttcta ttccagtaag attcatcttt ttattccatt caactaatat
   132121 ctctctatag attttaaatt tttctaacat actgtcattc gtatctatat taaaaccttc
   132181 aatcccgttt ttcagaagtt ctatattatt cacctttgcc acctctagtt cttctgattt
   132241 gttctaggta tataagtaaa actgatatat cagctggaga aacaccagat atacgagatg
   132301 cttgccctat tgaaataggt tttatatcat ctaatttctg tctagcttct aatctaagac
   132361 cttctataga tgaataattt attttctcat ccaacttttt attctcaagt tttttaaatt
   132421 ggtctatttg tttcaattgt ttctctatat aaccttcata tttagttatt attacacact
   132481 gttctttaac ttctcttgaa acatcttctc cagcgccttt ccctaattct tcaagcaatt
   132541 cgtaagtaac ctctggtctc tttaaaaatt catatagaga tattccaacc tttattggtg
   132601 ttgctccttt ttcttccaac aaactattta cttcttttgg tgtaactctt tcatttttta
   132661 gtctttcaaa ttctttctct acagcagcct ttttatttag gaacctttca tatctatctt
   132721 ttttaactaa tcctatatca taaccttttt gagttaatct catatctgca ttatcttgtc
   132781 ttaaatatag tcgatattct gctcttgatg tcatcattct gtaaggctcg ttagttcctt
   132841 tagtaacaag gtcatctaat aagacaccta tataagcttc tgaacggtct aatacaaatg
   132901 gctcttttcc ttctatcttt ctaactgcat ttataccagc cataagccct tgagctgctg
   132961 cttcctcgta tccagaagtt ccattaaatt gccctgcact aaataagttc tcaacaccct
   133021 ttatttccaa acttattttt agttgagttg ggtcaacaca atcatattca atagcatatg
   133081 caggtctcat tatcttacaa ttttcaagtc cttttatagt tttgtacata tctaattgaa
   133141 cttcaaaagg taaactagtt gaaattcctt gtatatacat ttctttagta tttaaccctt
   133201 ctggttctat aaataattga tgtgatgttt tatcactaaa tcttactact ttatcttcta
   133261 tagaaggaca gtatcttgga ccagtacttt ctattactcc actatacata gcagaccttt
   133321 ttaaattatc cagtataact ttttgagttt cttctgtagt tcttgttaaa taacaaggtt
   133381 cttgtttttt ttctatattt tcattcataa atgagaatgg agttactttt tcatcaccct
   133441 cttgtaaaga cattacagag aagtctatac tatctctatg aactcttgct ggagttcccg
   133501 tcttaaatct tctcattcta aggccaagct caactaagct atctgtaaga tattttgcat
   133561 accctaatgc attaggacct tcataaaatg caacttcacc catatatatc tttgagttca
   133621 gataaactcc agtggccaat attacagctt tagatttaaa tgaacatcct agtttagttc
   133681 caactcctat tacaacattt ccttcatgaa gtatttctac aacttcatcc atagctatat
   133741 caagatttgg ttcatcttct aatgtctttt tcatttcttc atgatattta aatttatctg
   133801 cttgtgctct taaagagtgt accgctggac ctttggcagt atttaacatt ctactttgta
   133861 tatatgtctt gtctatattt aatcccatct gaccgcctaa ggcatctatt tctttaacta
   133921 attgaccttt accagtccct ccaattgatg gattacaagg cattaatgct atggaatcca
   133981 aagacattgt tattatcaaa gttttatatc ccattcttgc agtagccaaa gcagcttcac
   134041 atccagcatg tcctgctccg actactataa catcatattt tcctgcttca aactttatca
   134101 tttataattc ctttcttttc aaaattaatg tttcatgaga aacacttcaa attttttaaa
   134161 aatctctata ataaaaacaa gtttactttt gtacattact taccaataca gaaattatgg
   134221 aatatattat ctagtaaatc ctctgttact gtatcaccat taatatatcc aagatagtcc
   134281 catatatttt ttaaatcgac ttctacaaag tcaaatggca tactttgttc caaagcaatt
   134341 aaagcatctg ttgcagattt atatgcttta ctaagtgcat ctttatgtct tgaatttgtt
   134401 actactaaac tagaattatt tttgatacta cctttatata ccatagactc tattttatct
   134461 tgcaattctt ctattccttc ttgttgtaaa gctgatattt ttattatact attattttct
   134521 acatatttaa gtattttttc ttcttcaatc tcttgtttca aatcattctt atttaacagc
   134581 actattgttt gtttatcctt aagtttttct aatatctcta tatcttcttc tgacaacttt
   134641 ctagatgcat ctaaaaccat tactatcaaa tctgcactag taaatgattc tttagacttt
   134701 tcaacaccta ttttttcaac aatatcatca gtatctctta tacctgctgt gtcaacaatt
   134761 tttaaaggta taccttttat gtttacaaac tcttctataa catctctagt agttcctggt
   134821 atatcagtaa ctattgctct attctctcct aaaatagaat taagtagtga agatttacct
   134881 acatttggtt tcccaacaat taccgtcttt aagccttctc taagtatttt tccactttca
   134941 gctgtatcat ataatttttt aatgtctttt ttaagttcat cagttttttc tttaagagtt
   135001 tgatatgtta tatgctcaat atcttcctca ggataatcta tagcaacttc tacatgagct
   135061 aatatctcag tgactttatc tctcaattct cttatcttct ttgataaaga accctctaat
   135121 tgattttgag caacttcatg agctatatca gttttggctt ttataacatc aattacagcc
   135181 tctgcttgag ataaatctat tcttccattt aagaatgctc ttttagtaaa ctcaccagcc
   135241 tctgctaatc taacatcttt tgatagtatt aattctaata tcttctttac cgaaataaat
   135301 ccaccatggc aattaatttc tataacatct tctcctgtat aggaatttgg tcctttcata
   135361 tatgccaata aaacttcatc aattacattt tcattatcca ctatatttcc atatattaat
   135421 gttctcttat tgtattcttc aatactcttt ccagacatag atttaaagat ttcttctgca
   135481 accttcaaag ctttttctcc acttattcta agtataccta taccaccttc tccaggtgct
   135541 gtagctattg ctgcaattgt atcatctata aacaaattta tcacctctta attcataatt
   135601 ttttacatat agatttacat ttaaccaacc attaatgatt taataatatt aaaaaataaa
   135661 accccctaat gtttaggagg ttgactttat cttttacact caattactaa tcttctatat
   135721 ggatcggttc cttcactata tgtaattaca tatttgtcat tttgaagagc tgaatgtatt
   135781 attcttctct catatggatt catataatct aattttttag tttttcttgt tttcgctact
   135841 tctctagcaa ctttattagc atatcttatt aaagattctt ctcgttttga tctataattt
   135901 tctatatcta caagtactct tgtatgagaa tctttattta ttttattaag agctaatcca
   135961 gtcaaaaatt gaatagaatc taaagtttcc cctcttctac caattaaact tgcagcttct
   136021 ttgccttcaa tatcaaccat gattaaatta tctttttgag atacattgac tttggcatca
   136081 acatttgcat ttttcaacat tacctctata aaatttttag ctacatctac ttccctctcg
   136141 ataacaaaaa tttcataagt accatcttta gcacctataa aacctaaaaa ccctttactt
   136201 ggattttcaa gtatttctac ttctatatcc tctgctttta aattcaactc tgctatagct
   136261 ttacttatag cttcctcttt actcttactt tttattaatt ttaggctttt tctcattaac
   136321 tttttcctcc ttagagttag cagccagttt agcttttaaa ggattcatta ttaagtaata
   136381 ttgagctatt gagaataagt tacttactgt ccagtacaat gtaagtcctg ctgggaatat
   136441 aaatccccaa tagaaagaca tacctgccat tacatatgtc attactttca tagagccttg
   136501 taactgatct tttggtgtca ttactttttg catgacatat gcacttgctc ctgaaaatac
   136561 tgctaataca taatctggtg atgttaagct ttttatccat aaaaacccat tgtcagctgc
   136621 taaaaatgca gctttgtttg caaaaacgcc atgagcaact ggttctctca aaacgctaaa
   136681 taatcctatt aatataggaa actgtattaa taaaggtaaa caaccagata gtggattaat
   136741 tttagcttct ccatataact taacaatttc ttcattttgt ttttctggct tatttttata
   136801 tttttcttgt atctctttta tacgaggttg tatatcttgc attgcctttg ttgacttagt
   136861 ctgcttaatt gttaatggta ataaaataat ctttacaagt atcgtaaaaa gtattataga
   136921 aataccataa tgattaacaa attcaaatat taccttaaga atcaatccta agaaatttcc
   136981 tattatattc aattttttta tacctcctaa tagttactct cttttatttt agagggtcgt
   137041 aacctcctgg atgaaaagga tgacatttta aaagtcttct tatcgttaaa tacatacctt
   137101 ttacaaatcc atatttctta aacgcctcta ttgaatattg tgagcaagtt ggataaaatc
   137161 tacaggtagg tccctttaag ggagatatat acttttgata aaatctcact aaataaatac
   137221 ataaattcga taaatgctta cttatttcct ttaatatata aattatttta ttcaaagtca
   137281 ttaacctcca tatttatagc atacaattaa atagaaatat ccgttctttt aactaaattt
   137341 tttatagact tgtctatgtc tttaaaagta gcatccttac tagataccct tgctataaat
   137401 actatatcat atccaggctt aattttttca tcaatattta atctgtaggc ttcttttatt
   137461 aatcttctta ctctattcct agtaatagct tttcctactt tttttgaaac agaaatacct
   137521 actctactat aatctgattt atttttaagt atatatatta ctaaatattt gtttgcaaaa
   137581 gatttgccgt gtttatatac ttttctaaaa tcagagtctt ttttcaaccc tttagtccta
   137641 ttaaagtcca tagttaacct ccataaacac agctatgaat tgtaattatt tacacaaaaa
   137701 ggccaccttt gcagcggccc ttttgtaatt aatgagttaa tctatttctt cctttagctc
   137761 ttcttctctt taacacgttt cttccgttag acgtcttcat tctttttctg aaaccatgtt
   137821 ctttacttct ttgtctcttt tttggttgat aagttctttt actcattatt ttgcaccgcc
   137881 tttcagattt tattttccgt ttataaaaat aataacttta ccctcaaagt aaacataaca
   137941 catataatta taaatacttt tactactgtt gtcaacgagt ttttgggacg cttatatcac
   138001 aaaatctacc atatatatat tatgtatttt ttttattgaa aatactagta aaaatctatt
   138061 taattttatt ctaaattatt tttttcaatt atatacacaa ataaagtaat tttaacatgt
   138121 ttatattttt atcaacaatt agttaatatt gtggataaat tagttacaaa tcattgaagt
   138181 ttgacatata ttttgatatt ataaatatac ttgttgataa tgtgcataaa tgttatcaac
   138241 ttattagaaa ttattcacag cttgtggata cttttgtgta taacttttaa gattactgac
   138301 aatactctag ttataatcac catttattgt atgtttatgt tatttataac tttatctaca
   138361 tattgtttat atcttttcat atttttttaa taatttatac tattattaat ttatcaacac
   138421 cattatccat aaatttagtt attctgtaaa atttatatat atttttgctt ttctgttaat
   138481 aactttgtgg aaaatattaa ttattctgtt cggaggttta tattatggat atagtttctt
   138541 tatgggacaa aaccctacaa ttaataaaag gtgacttaac ttcagtaagt tttaatacct
   138601 tttttaaaaa catcgtacca ttaaaaatac atcttaatga tttaatctta ctggctccta
   138661 gtgattttaa taaagatatc ttagagaata gatatttaca tttaattgaa gatgctatta
   138721 gtcaactgtc attaaaaaaa tataatatta aatttgtatt gagcgaaaaa gaggttgctg
   138781 atttaaattc tgatagcaca gatttaaatt atagagttct ttaccccaat ctaaatccaa
   138841 aatacacatt tgatacattc gttattggta atagtaatag atttgcacat gctgcatgcg
   138901 ttgcagttgc agaatctcca gctaaagctt ataacccact ttttttgtat ggaggagttg
   138961 gattaggtaa gactcaccta atgcatgcta taggtcatca tattgttagt caaaaaaaag
   139021 actcaaaagt agtttacgtt tcttcagaaa aatttactaa tgaacttata aactctataa
   139081 aagacgataa aaacgaagaa tttaggaata aatatagaaa cgtagatgta ttactaatcg
   139141 acgatattca atttatagca ggaaaagaaa gaactcaaga agagtttttc catacattca
   139201 atactcttca tgaagcaaac aaacaaataa ttatatctag tgatagaccg ccaaaagaca
   139261 tacctacact agaagatagg ctaagatcga gatttgaaat gggacttata actgatattc
   139321 aagcacctga ctttgagaca agaattgcta tacttagaaa aaaggctcaa ctagaacgta
   139381 tagatgtgcc aaatgaggtt atgtcatata tagcaaaaaa tattaagtca aacataaggg
   139441 aactagaagg tgcattaact agagtggttg cttattcttc tcttagcaat agggtaatat
   139501 cttttgatct tgctacagaa gctttaaaag atattataac aacttctaaa aatgaagaaa
   139561 taaatgttct cagaataaaa gaaaaagtat cttctgtatt caatttaaag atggaagatt
   139621 ttaattctaa aaaaagaaca cgttcaatag cttatccaag acagatagct atgtatttaa
   139681 cgcgcgagct tactgattta tcccttccta aaataggtga agagtttggg ggtagagacc
   139741 atacaacagt aattcatgct catgacaaag tatctaagga tatagaagaa agtgaagaaa
   139801 ttaagactaa aatagacaaa attatatcag atttgaaggg ataatttata cacaattgta
   139861 tgtttatatc tcttgaataa cctgttaata ctttttttga acaaaaatta ttaacaaatt
   139921 atcaagtcta aaataacaaa gatattaaca tcttatacac atgttaatat ctttgtattt
   139981 ataatgttat acatacttat taacattatc aacaacacct actactatta ctactatgat
   140041 tttaacttat ttttatatat aaaaagccag aggaggttat ccacattgaa aataatttgt
   140101 aatcaaaaaa tcctagcaaa tagaattgga attgctcaaa aagctattaa tggaaaaaca
   140161 acaatagaat tattaaaagg tatacttata tctacagaag aaggtcaatt aaaacttact
   140221 ggatatgatg ctgaaatagg aatagaaact tatgtacaag cagaaatcat agaaaaaggt
   140281 gatgttgttg tagatgcaag gctatttgga gatataatta gaaaattacc agattccttt
   140341 gttgagatag aaactgattc agaaaataat atttacataa attgtgtaaa ttcaagattt
   140401 aaaattaaag gttatgcagc aaaagaattt cctaaattac cagaattaaa tgaagaagat
   140461 ttatatagca tacctcaaga aatcctaaaa aatatgatta aacaaactgt atttgctatc
   140521 tcacaggacc aaacaaaacc tgttttaatg ggagaacttt tagaaattgt agatagaaac
   140581 ttaaatttag tagcaattga tggatataga ttagctgtaa aaagttgttc ggttgatagt
   140641 ttaactgaaa atataaaagt cataattcct ggaaagacac ttatagatgt aaatagtttg
   140701 ctttctggag aggataatgt taaagttgga tttaacgaaa aaaatgctat ttttataatt
   140761 aatgatacga aaattattac aagattgctt gaaggagatt ttattgatta taaaaaatta
   140821 ttgccaagag aacataacag cagagttaaa ttaaatacta aggaactttt aaatagtata
   140881 gagagagcgt ctttattgtc tcaatcagaa aaaaataatc ttataaagtt atctataaga
   140941 gataaagtaa tggcaattac ttctaataca gaaaaaggaa atgtgtatga agaagttgaa
   141001 atagatttag atggagatta cctagatata gctttcaatt ctagatattt tatcgaaggt
   141061 ttgaaaaata tagataatga ggaaatattt atagaattta ctacaaatgt aaatccttgt
   141121 ataattaaac caacagatga tgttaattat atttacttac tgcttccagt aagaatatca
   141181 tcaaatatat agcagacatg aaggagttgt cttttgtaga aaatttttct aatcttagac
   141241 aactcctttt ataagcatat ttatggtata atatactttt agtgtatcaa taggaatttg
   141301 tttaaaatag tgacaaggag gaactattat gactgaaata actatagaat cagaatatat
   141361 aaagttggat caatttctta aattagcaga gattgcatca acaggaggtc atgcaaaatt
   141421 tttaattcaa gaaggtttag tgacagtaaa tgatgaaata gaattaagaa gaggaaaaaa
   141481 gataaaatca ggagatatag ttgaaataga aggaactaaa ataaaagtat tgtaaaaaag
   141541 gagaactttt tgtgaaactt aaaagtttgc aacttgttaa ttttagaaat tataaaaagt
   141601 tgcatctgga atttaatggg aaagtaaatc tacttgttgg taaaaatggt caaggaaaga
   141661 caaatatagt agaatctatt tatatgcttt cttttggaaa atcatttagg actaacaaag
   141721 ataaagaaat ggttagattt aatagtgaaa acttatatat tggaggaagt ttttcaaaat
   141781 ataataaata tagtctaata gagctaatta ttggaaaaga taaaaaaggg ataagaataa
   141841 ataaagttcc tttacaaaag atacaagaac tacttggcaa cttaaatgtt gttatatttt
   141901 ctcctgagga tttaaggttg gttaaagagg gtcctaaaga aagaagggca tttatagaca
   141961 aagagattag tcagattata cctaaatatt ataaatatct taccaattat aataaaacac
   142021 tttctcaaag gagtagggtg cttaaaaata tacatgttga tgaagcttta ttagatgtat
   142081 atgatgatac gttagcaaag tatggaagtt atatttatat tttgcgtaga gactttataa
   142141 aaaagatagc taatatatct gaaaatatgc atatgaattt gactaatgga gttgaaagat
   142201 tatcaattcg atataaaaat caaataaata taactgatga agatactata gatacagtat
   142261 ataataaatt tttagccaag ttgtcatcga atagacctaa tgatatagaa tctaagacta
   142321 ccagatatgg tatacacaaa gatgacttaa atatattcat aaatgattta gatgcaagac
   142381 tttttggttc acaaggtcaa caaagaactg cttcaatatc attaaagtta tcagagatag
   142441 aattaataaa aaatgaagtt gaagaatatc cagtattaat tttagatgat gtttttagtg
   142501 agttagatga agcaagacaa aaacttttag taaataattt aagcaatgtt caaatgttta
   142561 taacaagtgc tgaagtttca cataaaaaaa tatttgatga aaaaaatgtt acaatattta
   142621 atattgaaaa tggcgatgtt attagcatag agaatggagg aaattaaatg aaacaagaat
   142681 acggtgcaag tcagatacaa gtattagagg gattagaagc cgttagaaaa agaccaggta
   142741 tgtatattgg tagtacaagc cctagaggtt tacatcactt agtttatgaa gttgtagata
   142801 atagtataga tgaggcttta caaggatatt gttcagacat atatgtatct attaatgaag
   142861 atggcagtgt tttagtaaaa gataacggaa gaggtatacc tgttgaaata catcctaaaa
   142921 ctggtaaatc aactttagaa acagtattaa ctaatcttca tgcaggagga aagtttggag
   142981 gcggaggata taaagtatct ggaggtcttc atggagttgg tgtttctgta gttaatgcat
   143041 tgtcaaaatg gatggtagca gaggtttatt taaacggaaa gagatataag cagacatatg
   143101 agaaaggatt gccaacatct aagcttgaag tagttggaga atctcaagat aaaggaacaa
   143161 tgattcaatt tatgccagat gagacaatat ttgatgaaat agagtttaaa tatgaaacat
   143221 tggagtatag gcttagagaa ctttctttct tgaataaagg aataaaaata gtatttgaag
   143281 ataaaagaga aggacaagaa aaaagaaaag aatttcacta tacaggtggt ttggtagaat
   143341 atattaagta tttaaataaa tctagaactg gtatacatga tgacatagtt tatatagata
   143401 aaaaggttga tgattgtttt gttgaactag ctatgcaata tacagatggt tatacagaga
   143461 acatatattc ttttgcaaac aatataaata cacatgaagg tggttctcat ttaagtggat
   143521 ttaaagcagc tcttactaaa actgtaaatg attatgctaa gagaaataaa tttttaaagg
   143581 aaaatgatgt taacctactt ggtgaagaca taagagaagg tcttacagca gtagtatcag
   143641 ttaaattacc agaacctcaa tttgaaggtc aaactaaaac aaagctaggt aatagcttta
   143701 tgagaggtat agttgatagt gtaacagttg atgaactggg gtctttccta gaagaaaacc
   143761 catcaacagc aagaatcata gttgataaag ctttaagagc acaaagagct agagaagctg
   143821 caaaaaaagc aagagaatta acaaggagaa aaagtgtatt agaaagtaca tctttacctg
   143881 gaaaacttgc agattgtgca gaaaaagatc catctaaaag tgaaatattc ttagtcgaag
   143941 gggattcagc gggaggttca gctaaacaag gtagagatag aaatagtcaa gctatacttc
   144001 cattaagagg gaaaatactt aatgttgaga aatcaagact agataggata ctatcttcag
   144061 atgaaataaa aaatatgata acagcttatg gttgtggtat tggagaagat tttgatatag
   144121 ataaggctag gtatcataaa attataatta tgaccgatgc tgatgtagac ggagcccata
   144181 taagaacttt attattaaca ttcttcttta gatatatgag acctcttata gatgaggggt
   144241 atgtttatgc agcacagcca cctttatata aagtgacaaa gcaaaagaag gaacattatg
   144301 tttactcaga taaagagtta aatatcttat tagatgaaat tggaagaaat ggtgttgaac
   144361 ttcaaaggta caaaggtctt ggagagatga atgcagagca attatgggaa acaactatga
   144421 atcctgagac aagaacttta ttacaagtta ctgtagaaga tgctgcaatt gcagatgaag
   144481 tattttcaat gcttatgggt gataaggttg ctccaagaaa agaatttata gaagaaaatg
   144541 caagatttgt tagaaactta gatatataga gagaggggat tagtatacat ggaagaaaat
   144601 aacaaaatac tccctattga aatagcggaa gaaatgaaaa aatcgtatat tgattattca
   144661 atgagtgtta tagctggacg tgctcttcct gatgttagag atggtttaaa gccagttcat
   144721 agaagaatat tatattcaat gagtgagtta aatttaactc cagataaacc atacaggaag
   144781 tcagctcgta ttgttgggga cgttttaggt aagtaccatc ctcatggaga tactgctgtt
   144841 tattatgcta tggtaagaat ggcacaagat ttttcaacta gagcactttt agtagatggt
   144901 catggtaact ttggttctgt tgatggggat tcaccagctg ctatgcgtta tacagaagct
   144961 aaaatgagta aattatcatt agaactactg agagatattg aaaaggaaac tgtagacttt
   145021 aaaccaaact ttgatgagtc gttaaaagag ccttcagtat tgccagctag atatcctaat
   145081 ttattagtaa atggctcaaa tggtatagct gttggtatgg caacttcaat acctccacat
   145141 aatttagcag aagtaattga tgcaactgta tatttgatag ataatccaga gtgtagtgta
   145201 gatgatttaa taaaatttgt tcaaggacca gatttcccta cagctgcaat tataatggga
   145261 aaagaaagta tagcagaagc atacagaact ggaagaggaa aagttaaagt taggtctaga
   145321 gcttttatag aagagctacc aaaaggaaaa cagcaaataa tagttacaga aataccttat
   145381 caagtaaata aggctaaact ggttgaaaga atagcagagt tagttaaaga aaagagaata
   145441 gaaggtatat cagacctaag agacgaaagt aatagaaatg gtatgagaat tgttatagaa
   145501 ttaaagaggg atgctaatgc taatatagta ttaaataatt tgtataaaca ttctcaaatg
   145561 gaagatactt ttagtataat aatgcttgca cttgtagatg gtcagccaag agttttaaat
   145621 cttaaacaaa tattatatca ttatattaaa catcaagaag atgttgttac aagaagaact
   145681 aaatttgaac taaataaagc tgaagcaaga gcacatattt tagaaggatt aaagattgct
   145741 ttagataata tagatgctgt tataagcttg ataagagctt caaagactgg gcaagaagct
   145801 aagctaggtt taatagaaaa attcaaatta actgaaatcc aagcacaagc tatattagat
   145861 atgagacttc aaagacttac aggtttagaa agagataaga tagaagctga atatgaagat
   145921 ttaatcaaga agataaatag attaaaagag attttagctg atgaaagatt acttttaaat
   145981 gtaataaagg atgaaattac aataataaaa gaaaattact ctgatgagag aagaacagaa
   146041 ataagacatg ctgaaggcga aatagatatg agagatctta taagtgatga agaaatagca
   146101 ataactctta ctcactttgg atatataaaa aggcttccat ctgatactta taagagtcaa
   146161 aaaaggggtg gaagaggtat ttcagcactt acaactagag aagaagattt tgtaaggcac
   146221 ttggtaacta caactactca tagtagacta ttattcttta caaataaagg tagagtattt
   146281 aaattaaatg catatgaaat accagaaggt aagagacagg ctaaaggtac tgctatagtg
   146341 aatttacttc aattgtcagc agatgagaaa attgctactc taatacctat tgatggtaat
   146401 gatgaaaatg aatatttatt acttgcaacg aaaaaaggta ttgttaaaaa gactaagaga
   146461 gaagagttca aaaatataaa taaatctggt cttattgcta taggtttaag agatgatgat
   146521 gagcttattg gagtagaact tacagatgga aaacaagaag tacttttagt aactaaagaa
   146581 ggtatgtcta taagatttga tgaaaatgat ataagatata tgggtagaac agcaatgggt
   146641 gtaaaaggta taactttaag taaagaagat tttgttgtgt ctatgaacct ttgcagtaaa
   146701 ggtacagatg tgttagttgt aagtaagaat ggttttggaa agagaacaaa tatagaagag
   146761 tatagaagtc aaataagagc tggtaaagga attaaaactt ataatatatc tgaaaaaact
   146821 ggtacaattg taggtgcaga tatggtcaac gaagatgatg agataatgat tataaattct
   146881 gatggagttc ttattagaat aagagtcaat gaaatatcac tgtttggaag agttacaagt
   146941 ggtgttaaat taatgaagac gaatgatgaa gtcaatgtag tttcgattgc caaaataaat
   147001 attgaagaag aataggataa atatcctatt ctttttgtat aatgtagtta gataaaaatt
   147061 taaaattgaa aggagtaatt gttatgtgca ataaaagaag ttgtaaaaaa ggtggatttt
   147121 tattattagg agctatttta gggtttatat ttggtatgtt ttttgcacct aaaaaaggtt
   147181 ctgaactaag aaaagaaaca aaagagaagt ttaatgatgt taaagaaaat ccaaaagaag
   147241 ttctacatga aacatttaat gatgttaaag agagaataat aaatttagtg gatgatgata
   147301 ataatgaaga agatataaag atttcagaag aagatatagt aataagtaaa agctttgatg
   147361 atgagggaga tgttaactaa tgaatgcatg ggggtggcaa attggagcag tgttagtagg
   147421 aagctctgct cttatagtag caatttattt agctaaaact ctaaacagca taaataaggt
   147481 tgttgaaaag gcatataaga ttgtagatta taatgaaaga catatacaag atattgttga
   147541 aaatgcatca tcaatatcaa agggaataga tgatatagtt tatgtaatta ataaaatatt
   147601 gagtatagga aatatattta aaattattaa aaggaaatag gaggttttta catgtctatg
   147661 aatattgatt caaatttaga ttcacaaaat aaattttgga atgtttgtct tgatggagaa
   147721 cttgatgttt ctacagcaga taaactaaag gaacatttac atgctttaat agaaaaaaat
   147781 atgttagatg taaagattaa tcttaaagat ttagattata tagactcaac aggcttagga
   147841 gctatgatag gtgtattaaa aaaattaaaa ataaatgaaa aagagatata catagtaaat
   147901 cctaagagta acgtaagaaa gatttttact ataacaggtc tagataaaat atttaaagtg
   147961 gagggataaa ctttggcttg tgagactata aagatggaaa ttactacaaa tccagattat
   148021 gttagtataa taagattaac agcatctgga attgccaata agatgggttt tccaatagat
   148081 gatatagaag atataaaggt agcagtatct gaagcatgta caaatgcaat aaaacacagt
   148141 aaagatgatg tatttaatat agtatttaat attttagata atgcaattaa tatagaaatt
   148201 caagataatg gaaaaggata tgatgttagc tcaataagta caccagattt agagaatcca
   148261 aaagagagtg gtcttggatt gtttataatt aaaactttaa tggatgatgt agatattgaa
   148321 tcagaacata atcaagggac aaaaataaaa atgactaaat atttaggagt tgatatttaa
   148381 tgaaaaatgt agctaatgct acacattacc taaatatgga tacaaaagag ctatttaatt
   148441 tatataataa aaataaaaat gtagacatta gaaatattct tattgaaaga catctgtatt
   148501 tagcaagatt gttagctaag aagtatataa acaaaggtgt tgattttgaa gatatatatc
   148561 aagttgcttc attggcatta atttatgcta ttgatagata tgatgttgag aaaggatttg
   148621 agttctccag ctttgcaaca ccaactatag taggagaaat aaaaaagtat tttagagata
   148681 aagtatggac acttagagtc ccaagaagaa tacaggaatt aagcaaaaag ataagtgatg
   148741 cgaagattaa attagaacaa gaaaataaga agcatccaaa ggtaaaagat atagctgatt
   148801 atataggcgt tagtgaagaa gatgttttag aggctatgga ggcttcttat ggatatcaac
   148861 caatgtcttt ggattcatca agtaatgatg attcagagga taaagatata actcttattg
   148921 ataagattgg aaaagaagaa ggtaactttg gaagtataga gtatgaagat tttattaata
   148981 agtttattga aactttaaat gaattagaag ttaaaatttt taaagataga tttttctttg
   149041 ataaaacaca atctagtata gctaaagaac tagggatatc acagatgact gtttctagac
   149101 tagagaaaaa ggtagtagag aagctgaaaa aagaatatga aaaaaattta taaaaaaata
   149161 taaaaaaagt attgacctac tgttttaaag atggtatagt attacttgtc cttgaaaaaa
   149221 ggaacaagaa ataaacacga acattgaaaa ttaaacagta ggttaattta tat
//
LOCUS       DAEPKC010000002       108974 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.002, whole genome shotgun sequence.
ACCESSION   DAEPKC010000002 DAEPKC010000000
VERSION     DAEPKC010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 108974)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 108974)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..108974
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.002"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(107..946)
                     /locus_tag="KR294_000151"
     CDS             complement(107..946)
                     /locus_tag="KR294_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBH0238269.1"
                     /translation="MSDIKNEVSKKMLSKKDVIKSWLRWFFFAQSNYNYERLQSTAFS
                     HSMLPVLKKLYPDKEELKQEVETHLAFFNTEPICGCVIHGITIAMEEEKANGADEISG
                     DGMNAIKTGLMGPLAGIGDTLTQGVITPIVLAVCIGLTEGGASIAGPILFVIAQYIIM
                     TSISFGMWTNGYKYGKKAVESILQGGIVNKVIEGASILGTLVMGGLVGRFINLSTPIS
                     YTSGDFKFSLQTDLLDKIFPGLIPLVLTLLVLFALKKGLSPIKIMFILIVVGAITGIL
                     GLF"
     gene            complement(970..1728)
                     /locus_tag="KR294_000152"
     CDS             complement(970..1728)
                     /locus_tag="KR294_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH0238270.1"
                     /translation="MHISLIQAVLIAIFYYLSWSPWLTYVGFFTWNRPLLAGFVTGII
                     LGDPVQGAIIGAGINMIYLGFISAGGAQMGDPAFAGYVGTALAIASKLDVSTAMAIAV
                     PLGTVATVLWIGKMTVNSFFAHWADREVQKGNVDRVAFINIVPPQILLFAMSFIPALL
                     VVYFGPNAIDGMLEVMNDNVLHVFNVIGAMLPALGIAMNLKLIGNKFTMPFFILGILM
                     AVYFKVDIIVISVIGVILALTITSIKYGKDSATS"
     gene            complement(1775..2248)
                     /locus_tag="KR294_000153"
     CDS             complement(1775..2248)
                     /locus_tag="KR294_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH0238271.1"
                     /translation="MSNIALTRIDDRLIHGQVITAWCKITSAKRIVIVDDLVVKDPFI
                     VQVLQMAAPSTVKVEVHNVESGAEVLKSHNGDENLIVLVKYPKTVLGLVNSGVDLKEL
                     NVGGMGAGLGRKSFYKNISVSDEEKEIFRELISKDIKCFIQIVPDAKKIDVGTLL"
     gene            complement(2277..2693)
                     /locus_tag="KR294_000154"
     CDS             complement(2277..2693)
                     /locus_tag="KR294_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH0238272.1"
                     /translation="MIHMAGIIIATHGNMAKAMLESAELIVGKQENVETLGLNHGDSI
                     DEFSRKLEDGIEKYKDEGVLVLLDFYGGTPFNTSAIIINKFAKVCELECLTGVNLPML
                     LELFLNRDTMKLKDLKNLCEEVGISGIKDVKTVLKL"
     gene            complement(2740..3792)
                     /locus_tag="KR294_000155"
     CDS             complement(2740..3792)
                     /locus_tag="KR294_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HBH0238273.1"
                     /translation="MKSVRFYGIRDTRVEDVDVPKILEKDDVIIKVKVAGICGSDISK
                     YSKTGPHMVGEILGHEFSGEVAQVGKEVRSFKIGDRVAVCPAMPCFECDECKKGLYSR
                     CNNVAIIGNKELVGCFAEYTKVKERNLIKIPDEISYETAAALEPVCIAGHGLFRSEAK
                     VGDTVVVLGTGPIGLFSIQWAKIFGSTKVIAVDVFDEKLDLAKELGADICINAKEKNI
                     VEEIKRLTDGDGADIVIESAGTPLTCGQVLLLAKKGGTVLYAGVPYGDVALTREQFEK
                     IVRSELTVKGTWFGNSFPFPGKEWSAGLYHMQKGDMNVEKLVTHRINLEEVPAYFEKV
                     YKRDIFFGKIMINIDN"
     gene            4188..4868
                     /locus_tag="KR294_000156"
     CDS             4188..4868
                     /locus_tag="KR294_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HBH0238274.1"
                     /translation="MKKVYQGKTKDVFELDNGNYLLKFKDDVTGKDGVFDPGENSVGL
                     SIDGIGRANLETSVKFFEILNNAGIKTHYVSANLEEATMEVLPAKVFGNGLEVICRYR
                     AVGSFLRRYGSCVEEGAKLDCYVEATLKDDDRCDPLITSEGLEALNIMTQAQFDSMKS
                     MTQKISNIVRDTIAEKGLELYDIKFEFGFYNDEVILIDEIASGNMRVYKDGVIVDPMD
                     LTALLLDK"
     gene            complement(5001..5321)
                     /gene="sugE"
                     /locus_tag="KR294_000157"
     CDS             complement(5001..5321)
                     /gene="sugE"
                     /locus_tag="KR294_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000118520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quaternary ammonium compound efflux SMR
                     transporter SugE"
                     /protein_id="HBH0238275.1"
                     /translation="MKWLFLFVAGLFEVFWAFQLKNSHGFSKLTPSILTVVGMIVSFY
                     FLSLALKHLPLGTSYAIWTGIGTVGTAIVGMAILNEPISISRIACIGFIVVGIVGLKL
                     LSTN"
     gene            5703..6530
                     /locus_tag="KR294_000158"
     CDS             5703..6530
                     /locus_tag="KR294_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="HBH0238276.1"
                     /translation="MNFYKIAVCQMITTENKIENINHAVDMVTEAAINGAKIVVLPEM
                     FNCPYENKYFPKFAEEYPGETTTILSKLAEKHGIYLVSGSIPELEDGKIYNTCYVFDK
                     NGALIGKHRKMHLFDIEVTGKVSFKESDTLTAGNDVTVIDTEYGKVGIAICYDIRFPE
                     LSRLMALKGAEIVILPAAFNMTTGPAHWELSIRMRALDNQIFYVGAAPARNMNASYIA
                     FGNSRISDPWGRIIAQADEKECIIYADIDRDLIPDIRQQLPLLKHRRTDLYELNTLK"
     gene            7352..8026
                     /locus_tag="KR294_000159"
     CDS             7352..8026
                     /locus_tag="KR294_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0238277.1"
                     /translation="MNNKILVVDDEEGIITLLKDYFEMNGYEVYTAQSGKDALKKISK
                     NPDIILLDINMPEIDGIEVCNRIRDYVSCPILFLTARIENTDKINGFRAGADDYIVKP
                     FDLDELGARVSAHLRREQRKSNQTKIKFYNDLTIDYEKRLICIYNNQISLSKKEFDIV
                     ELLSMNPGQVFDKEKIYDRVWGYNSNGNSDVIMEHIRKIRIKLSKHTLENYIETVWGV
                     GYKWIK"
     gene            8014..9174
                     /locus_tag="KR294_000160"
     CDS             8014..9174
                     /locus_tag="KR294_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBH0238278.1"
                     /translation="MDKINNMSLKKAFFVLTLSSLIIASVLTTFAYILLNNLYNSIQD
                     KYLKTPINTGIITIVQNNVNQFSDYDKTLLNIINILQLVLPLIFFIGLLLLADIIFYK
                     VKLKTPIEILNKGAMEISNNNLDFCLEYNNNDELGNLCNAFEKMRSELNKNNIKMWTM
                     INDRKQLNAAFSHDLRNPLTVLKGYSNYLTKYIPTGKLSDEKILSTTQLMSEHINRIE
                     YYVENMSNAQRLEDLVVSKSMSNINKFIENLDENISIIAKQEGKSFTLKNQINNINLF
                     FDENIILRVVENIISNAFRYARNNVSILIYLEQELLTFVIEDDGIGFSKESLKLALRP
                     FYRDKTLNDSNAHFGMGLYISKILCEKHGGSISIENNSTNSAKITAKFSTRN"
     gene            9390..9917
                     /locus_tag="KR294_000161"
     CDS             9390..9917
                     /locus_tag="KR294_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014118918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HBH0238279.1"
                     /translation="MKSFANNITFSRIVFALLMLSSTFCSLPFWICYFWCGISDILDG
                     LIARKLRQQSGIGAKLDSIADFIFAVTILVTVGKNIALPMYLWWCIVAIALLRLISYS
                     IGFFKYRTFSSLHTLMNKITGISIFAFPLLYICFGLDVAGIMICIVAFLSSFEEIAIM
                     IKSKELNRDIKSIFM"
     gene            10203..10871
                     /locus_tag="KR294_000162"
     CDS             10203..10871
                     /locus_tag="KR294_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0238280.1"
                     /translation="MIIKAKQLSKIYGSNNNKVIALNNVNLEINSGEFVSVIGPSGSG
                     KSTLLHILSGLDNPTSGQVLLDDKDIYKHTEKELSALRRKSFGFVFQQFNLLPVLTAS
                     ENISMPVLLDKKQPDKGYLNEISSLLGIADRLNHLPHELSGGQQQRVAIARALIAKPD
                     IIFADEPTGNLDSKSGSEVMNLLIKTSKQFGKTLVVITHDDRIAKLADRKISIIDGVL
                     MEVK"
     gene            10874..13342
                     /locus_tag="KR294_000163"
     CDS             10874..13342
                     /locus_tag="KR294_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0238281.1"
                     /translation="MKNYLSLSIKELKSQKLMTTFIIIAIVLSTIMTTVVGQSIGILQ
                     NLRIEQARSFNGDRHVSFHQLTKNQVDDIKKDDRVYQAGTSITIGSSKIKDSGISVLV
                     KEYDKTGLSNYPKLMKLKSGHLPKDKNEIALDENTLKLMGIKPRLGVTIPMNLDISLL
                     NDTIPPYNYTANFKLSGILEDDYTGYVSGIVNGIVGKGTSENLLPKRYTLSSLDFKIK
                     QQEKFQEIVNQLAKKINLSHNSIQYNWIYLNALKIQFEKDENSSNSDGISMIILVSLF
                     VALLVLLASGLVIYNILKISVTKKIKEYGCLRAIGAEPNQIYKIVILQILILCTVAIP
                     IGAVIGIISSKGITGMVTNILNPDILLANDNKEITELIHKNTTAYMFPLVLSTNVSLI
                     FSFISALPSAIYASHVSPKIAMVGSTTKIKRKIKREKTIKNFERHLAWLNLKRNKGRT
                     IITILSLFMSITVFVALSEFSNVLDVSRSVSNLKEGDFSLTNEISGFDKSTLDKIAKM
                     KNVNRTSFIKYSEYKQGEIDTDINFENSGEMLKIIGIDEQTLKDLMPSITDSILEDFK
                     NGSICFIKNPIAISTPGVKTRHTNLKPKDSITINKKQLDIYSTVDKMFFLQGNGWING
                     VDVIVYDSVYNTLTNKNKFNQINIYAKDKSKLEQIRLSIEQICENNPGSHWISYIESD
                     KQLKESFKQIEFLAWAVILFVGLIGTLNIINTTHTNINTRTNEIGVKRAIGMSNSSLY
                     KMFLWEGVYYGIFAAIFGSIAGYASAIIINMATIEKLDFTNIPITSILQATIISVLAC
                     IIATLIPLRKVKKMNIIDCIDINL"
     gene            complement(13582..15006)
                     /locus_tag="KR294_000164"
     CDS             complement(13582..15006)
                     /locus_tag="KR294_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH0238282.1"
                     /translation="MKNQSLITQFRHTFIFIIIASIVATVITYVFALYLYIHSLNKDI
                     YPPNYYERQVPRIEKYINEKNITLLSQSNEEGLKRTIRGDDMLYQVVDNNGNILYGTN
                     PKKLFKTKEELFNNFINKTVRKGGYIHTVPIKGDNGKIEGAVILFYQVKITFANIRGR
                     FVFAVIIMALFSPFLYIVGFTRWLSKRFVKNINQPLHLLIDASKKIKEKDLDFEIDYY
                     SDNELGKLCSAFSEMKDELKGSLSAQWKMEQERVEMVEALAHDLKSPLSIILGYTDAL
                     IGNNTDDNEKLHRYLTVIRENTEKSAALVQKMQYTSDLEKSNIQLNLVPINLPEFLRQ
                     KVQDYELQAHQKEVELILKMQGNIQSPIQIDVDRLTRIFDNIISNSLQYTPSGGNISI
                     TVKDEKNCISYEICDSGRGFSSKDLKKALDKFYRGDEARQTKGGHSGLGLYIVKQLVE
                     QLGGSVKIENSKSGGACVKFWHSI"
     gene            complement(15025..15717)
                     /locus_tag="KR294_000165"
     CDS             complement(15025..15717)
                     /locus_tag="KR294_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0238283.1"
                     /translation="MSKILIIDDEMDLVMLLEDELKAKGHEVLIAYDGQAGIELSKQE
                     PDLIILDIMMPKMNGFEVCQAIRDDVLCPIIFLSAKQSETDKIKGLTFGGDDYVTKPF
                     GLRELMARIEANLRREKRSQYINEENKRSTLYFGKLCLYMKERAIKIDGKNIDLTKIE
                     YDIVELLALHAGQVFSREQIYEKVWGCDSEGDSSTVVERVKKIRAKFSAVTPEKEYIS
                     TVWGIGYKWNKM"
     gene            complement(15772..16548)
                     /locus_tag="KR294_000166"
     CDS             complement(15772..16548)
                     /locus_tag="KR294_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutG family
                     permease subunit"
                     /protein_id="HBH0238284.1"
                     /translation="MIKLLSSEWLRAKRTAVQWLTLFMPIIFSLCVVFYLTTKSGSTQ
                     EFAFEGFFTVWTVFIIPIGVGILAGFIVQEEELAGNFNGFLCVGISRVRLYLGKFLFL
                     LFCLTICTFIATLILCIGMSIAVPSGATIWLFLSAAGLVVIGTLPLLAIHLWVSFAWG
                     MGASIGISIGGILMAAILGLTSVGEKVWAFVPWTWPVKLGMLPGIYFIKEAGTISTEA
                     FYSKVMQTASIELIVVAIGLIIFLIGGVIWFKMWEGRKSY"
     gene            complement(16545..17315)
                     /locus_tag="KR294_000167"
     CDS             complement(16545..17315)
                     /locus_tag="KR294_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutE/EpiE
                     family permease subunit"
                     /protein_id="HBH0238285.1"
                     /translation="MNALQSELLKYKRTFMGKLIVFFPVSFAAYAFIMQSTLMQNPLS
                     QTTSWAWQSLLALIFNWWSFLFLPIGFALFATLVAFQEKKAGNYRALRTHNVSPMTLW
                     INKVIAMAVYSFISTLVLIVVTIITGLILKAGPVPFGQIIGASIVCWVVSLAILPLQL
                     WLATWKGMFLSMGVGALGMIFGVLAATKPFWIAVPWSWAVRMVCPIINIHPNGTILEA
                     GDPLLNTSVIPIGIVVSLVVFIVLTALTAAWFNRRDDK"
     gene            complement(17312..18016)
                     /locus_tag="KR294_000168"
     CDS             complement(17312..18016)
                     /locus_tag="KR294_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic protection ABC transporter
                     ATP-binding protein"
                     /protein_id="HBH0238286.1"
                     /translation="MKDLILETKNLSKRYGEQMAVNNVSLQIERNSIYGLLGPNGAGK
                     STTLKMLVGLLRPTNGRIIFDRKPWKRESLAKIGSLIESPALYGNLTAEENLLVHTKI
                     LGIPKDKIYEVLEIVNLKNTGKKRASQFSMGMKQRLGIAIALLSDPELLILDEPTNGL
                     DPFGIQELRELIASFPKKGITVILSSHILSEVAQVVDNIGIINGGRLLFQGMPDPNEN
                     LEEFFTDVILKGGQNR"
     gene            complement(18271..18783)
                     /locus_tag="KR294_000169"
     CDS             complement(18271..18783)
                     /locus_tag="KR294_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0238287.1"
                     /translation="MKKISQEKISTHIQEVPQEKIEQWKSLYEKYKSILKVNSKSVLE
                     IIEFLKRKYVIVEETSEEFKHVVINNIKLNKPFSQKISSDKELKPIVFTIPNEGNAKK
                     LYDTQEEIYSGCKIIVGMEFETGYVFVEGSDELNDEITSFKGLDKYDINNYYLVANYI
                     RCLKKYKLID"
     gene            19109..19366
                     /locus_tag="KR294_000170"
     CDS             19109..19366
                     /locus_tag="KR294_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0238288.1"
                     /translation="MILNRAELFRGYSLNRFNEICNILSVNKIKYKYKVKNNAYSKKP
                     FFNEITLGNLGQKEDFSYEYLIYVHKDDYEQAESLINSKLR"
     gene            19509..20135
                     /locus_tag="KR294_000171"
     CDS             19509..20135
                     /locus_tag="KR294_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HBH0238289.1"
                     /translation="MKINIKSKLSEFIKQNNLFDDSRIISYLPNITIETDKIKTIMIN
                     EVVPTNTNDDFYSVDKDADYLKTTIPLFDSAGIKVSNINDILDMGIYITNAVKLPKSE
                     YTITRDTIKLHMPILEEEIKLFKNLEVVMLMGDVAKKSFNMITKKHIKKNVIPSISTY
                     KLRNNELYYDNLRVFPSYIMTGGNILIEKSKFEMASEDIKKMFEIING"
     gene            complement(20382..21161)
                     /locus_tag="KR294_000172"
     CDS             complement(20382..21161)
                     /locus_tag="KR294_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901940.1"
                     /note="N-terminal region resembles flavodoxins. C-terminal
                     ferrodoxin region binds two 4Fe-4S clusters; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EFR1 family ferrodoxin"
                     /protein_id="HBH0238290.1"
                     /translation="MNSKIYYFSGTGNSLVVSNILKETLNGSKEVIPLAIHRKENNID
                     INEDILVIVFPVYFADVPDIVKSFVEKLNFNINTHIYAIATCNGVAGHSLFTIDKLLK
                     KRGKKLSAGFLINMPGNALITPPDVEEERLKNQTNRVAEIAKCINNLEIGNIEGKNNL
                     KSHIDSVVLRLVGKNMQIATTKFFAENKCNRCGTCKRVCPVENISIVDKKPKWGNECE
                     RCLACFHWCPKEAINVKKSFLTNRKKYHHPDITVKDIFLDK"
     gene            complement(21229..21690)
                     /locus_tag="KR294_000173"
     CDS             complement(21229..21690)
                     /locus_tag="KR294_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBH0238291.1"
                     /translation="MGGARDYLNGGKMKDFEKLYEATTKLVSTSLKVKDDLKKMFKQN
                     GYDITTDHYALLRFLWEQDGISQIDLCEKSCKDKSNTTRILDVMKNKGLIVRKVDVKD
                     RRKFQIFLTDLGRELEEPLNEIASIYATETFKSISDEELPLFTDILDRIGK"
     gene            complement(21666..22343)
                     /locus_tag="KR294_000174"
     CDS             complement(21666..22343)
                     /locus_tag="KR294_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBH0238292.1"
                     /translation="MIITVINGSPRKNGATSKVLTYLYKDIERLIPDVKINYFDLSEV
                     NPSYCIGCLNCYKMGKCINQNDKVEYIHDIITKSDGVIFGSPTYGSSVTGLFKVFTDR
                     AHMMLERLLYRKPCIAVTTYENARGSKAISFIKSMVLDSGGYVCGSLSIKTGFNQNPI
                     TEKVESKIQKVSKKFIYCIEEKKNPPVLSQIYNFIAINAVLKPMAFKDIEQYKGIIDR
                     WEEQGII"
     gene            22576..22962
                     /locus_tag="KR294_000175"
     CDS             22576..22962
                     /locus_tag="KR294_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBH0238293.1"
                     /translation="MKKLPHISEAEYQVMKIIWKYAPISTTEVIEKLVETSTWSPKTI
                     QTMLLRLVKKGALTYEKNSRVFVYTPLVKEEEYVATESSSFLNRFYNGTLNSMVLNFL
                     ENDKLSEDDIEELREILNKRTTKGDK"
     gene            22965..24764
                     /locus_tag="KR294_000176"
     CDS             22965..24764
                     /locus_tag="KR294_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaR1 family beta-lactam sensor/signal
                     transducer"
                     /protein_id="HBH0238294.1"
                     /translation="MYAPFFIRFLLSTLTLSILIVVILLAKKVFKKHISAKYQYNIGF
                     ILLIMLIIPFVPLKYINLGNVFNYLYTFNQLGSSTNRTSMIKNSSNSVINNSNALNDF
                     SVSLNQVNFDSLNILLLISWIIGILIMIAITIHCNIKIKNMKKSIQILKDEEIVFIFE
                     KCKKDIGINKDFILCKSPIINTPITFGYFKPHIILPDKSISKLSLKDIKYILLHELQH
                     FKNKDILINYIMCFLQILYWFNPLVWYAFKEMRIDREIACDISVLKKLNKDSHIEYGQ
                     TLINFVDNISRPSNLTLTSDIGGSKKQIKKRLLKIMDFHNESNTLKFKSILIFTLIAL
                     IVFGNIPKLSIMADINEKYRPTNEQTVYEDLSQYFKGFDGSFVMYDLKSKQYHIYNKE
                     KSKTRISPNSTYKIYSALLGLENGIITRNNSHIPWDGKHHSNSSWNEDQDLFSAMENS
                     VNWYFQTLDKKTGLKNIQTYLRQIGYGNYDVSGGISNFWLESSLKISPIEQVELLESF
                     YTNKFKFEDKNIETVKDSLLISKKDGVSLFGKTGTANINGKDVNGWFIGYVEKNENTY
                     FFATNIQSKDYSNGSSASKITLSILNDKKIYNP"
     gene            complement(25119..26993)
                     /locus_tag="KR294_000177"
     CDS             complement(25119..26993)
                     /locus_tag="KR294_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBH0238295.1"
                     /translation="MNKYNKIANELIKIIGEDNIISITHCATRLRVMVKDREIINDKK
                     VEKVDEVKGVFFTSGQYQIILGTGIVNKVYAEVEKMGLKTLSKKEQDELVKNNETGFK
                     KVMRTLADIFVPIIPVIAATGLFLGLKGCLFNDNVLGLFGMSSANIPLYIQTLVSVLT
                     ETAFAFLPAIIVWSAFKVFGGTPVIGLVIGLMLVSPILPNAYSVADPSNEIEAIMAFG
                     FIPIVGCQGSVLTAIVTAFIGANLEKWFRKHMPNVLDLIFTPFFVMLITMLVILLGVG
                     PIMHTIELKMVDIISLLIDLPLGIGGFIIGFTYPLAVITGLHHTYVMIETSLLANTGF
                     NALITLCAMYGFANIGTCLAFMKKSKNNQVKQTAVGAMLSQLFGISEPVLFGIQLRYN
                     LKPLIIMCASSGLGAAILSILHIQSNSYGLAVLPSYLMYIYDGYNLITYLLVSIFVVA
                     FCFIVTCLFGVPKEAINEDEDEELVFNENNENFVSPAKGKIVALENVPDETFSKKMLG
                     DGFAIDIIDGKIVSPISGKLETVVSSGHAFGIKGTNGEVLIHVGIDTVALNGDGFDVA
                     VKQGDMVKQGDVLVNVDLKRIHELGKSTLTMVLFPDGKKVNILDINKDVKIGQRICVE
                     "
     gene            complement(26998..28662)
                     /locus_tag="KR294_000178"
     CDS             complement(26998..28662)
                     /locus_tag="KR294_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HBH0238296.1"
                     /translation="MEKKWWQKEIVYQIYPRSFQDSNNDGIGDLQGIISRLDYLKNLG
                     ITSLWLCPIFKSPMDDNGYDISDYLDIASEFGSMEDLKELIKESKDRGIKIILDLVLN
                     HTSDEHPWFQEALKNPESPYHDYYIFKKGNDLPNNWRSVFGGSVWEKVENRDEYYFHS
                     FGKKQPDLNWENPILRSELYQMINTWSQMGVAGFRVDAITFIKKNLSFQSLESDGVDG
                     LVKCTKTVRNQPGIEKMLYELKENTFKKYDCMTVAEAAGISYDQLGDFIGEDGFFSMV
                     FDFKHADLDVASGSEWFKRISWTIPDLRKCILDSQMYVQEHGWAANFIENHDQPRATT
                     KYLLQYERNDDAVKMLGAMYFFLRGTPFIYQGQELGMTNFKRDTINDFNDLSSIDQYY
                     RSIDESYSEEEALEFVNLRSRDNARTPFPWADKENAGFSDTTPWLKVIENYKDINAQS
                     QINNSESILEFYKKMIKLRQDSEYSDCLIYGSIEPIDIESDDIIAYRRQLDLVVIDCY
                     YNFSDKPVEIRVEEKYDIVFQNLDDINLLNKTVRLKPFHAVLLKVR"
     gene            complement(28676..29497)
                     /locus_tag="KR294_000179"
     CDS             complement(28676..29497)
                     /locus_tag="KR294_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBH0238297.1"
                     /translation="MKLYKLLILDIDGTLRDEVYGIPESAKHAIRLCQKNHCSVVICT
                     GRSMGTIQDDVLSLGVDGYIAGGGNYIQYHGELLYNQSFNQRLIKEVVCLLKKREVAF
                     SIESQEKVFMNQKAKEIFETMNQLKGTNSCINKQHIQEKITYENNIEEYKSQDIHKIC
                     LWSNEKVFDEVKNILQDKMELAQRDISSQYYEIIQKDFHKGKAIKRLQERLGVTQKET
                     ICFGDGQNDVVMFQASDVTIAMKNSHQQLKDIATSICEDIFDNGIYKELKRRNII"
     gene            complement(29596..30360)
                     /locus_tag="KR294_000180"
     CDS             complement(29596..30360)
                     /locus_tag="KR294_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBH0238298.1"
                     /translation="MKIEGLFNKYYNSFTANDKYICECILNHKEDCIKLSIDEFADKY
                     HISTSALSRFAQKLQLPGYSELRVIIRLNETEVEYKNQSKHQLMDCYNKVIDDIEKKD
                     CSIMFERMKKANRIIVFGEGYSQERVAKEMKRIFLPTGKIIYDVYGYDMIQALNHFIK
                     TDDMIFFISLNGDASTIIDFAKEMRMKGIYMVSITKMISNPLARLCDENLYIQSISIS
                     VDKQLDYDVTTPYFILIELLYIKYKMYLESEHIPRK"
     gene            complement(30357..31106)
                     /locus_tag="KR294_000181"
     CDS             complement(30357..31106)
                     /locus_tag="KR294_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBH0238299.1"
                     /translation="MRLESLVNQNYDNLNENDKIIIKQILICQREYRNFSCEKIANEC
                     NVSRATLLRLCRKIGLDSFSDLKYLLKNNQLEFVNNDNNFHDVCENYRLLMNELQKIS
                     FQDICKIIYDAETIYIYGTGNEQKSLAQEIKRIFLSVGKCVIDLFDIGEIEFMRESFQ
                     KNDLFIIISLSGETKAGIEIAKFINNHIHTISLTRLDNNTIATLCEYNLYVETQKLDT
                     LQAISYEVVGAFYALLDLLHMNYIEYRRRKE"
     gene            complement(31610..32215)
                     /locus_tag="KR294_000182"
     CDS             complement(31610..32215)
                     /locus_tag="KR294_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBH0238300.1"
                     /translation="MKIKENVLMLDSTRGSNCFIVFDKEIILIDTGLPFMGKNIIKEL
                     KTLGIKLTDIKHILLTHHDVDHISNIKLLKEKTGAKVWAHVEDIPFIIGEKDRPGFKK
                     FIGKAISRRLIKDVEPYGENMQIGNIKIIHTPGHTPGHVCMIFEAVLFAGDLVKNKNG
                     NIVPYPNPWNWDYKKMVKSIRELDNLKYEWICMSHGTPCIK"
     gene            32394..33032
                     /locus_tag="KR294_000183"
     CDS             32394..33032
                     /locus_tag="KR294_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH0238301.1"
                     /translation="MSELSKRDKEKIQRENEIIDKAEKLFCLNGFDNTTMNELAKEVE
                     YTKRTIYKYFSCKEDLFFAVVLRGYKRLWDNVKIESAKGKTGFEKIKLSYFAFHKFYS
                     VEPSLLCLMGMIGIVNSEKSDTDMLFKEKFFSFNKFMFDEIQGMFEIGKNDRSIRHDI
                     EIPTLMYSSIFTLTGFFNLLSVTGKSYLNNFNIDEEKFIETTLALLIDSIKA"
     gene            33164..33826
                     /locus_tag="KR294_000184"
     CDS             33164..33826
                     /locus_tag="KR294_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0238302.1"
                     /translation="MAKILLLEDDDTITFGIKTSLEKKNHTVCCYNTIAEAKKNFDKT
                     IDLILLDLNLPDGIGYEFCQYVKSIEDTPVIFLTVRDDEKDIIRGLDMGADDYVVKPF
                     LLSVLQSRINAVLRRTHSNTNNTITCENISLNKVEVKAYLDNVEVPLTAGEYKLLLSL
                     MENKNRAMTRTKLLEMLWDVDGNFVNDNTLTVTIKRLREKLKNPPCIKTLRGIGYRME
                     DS"
     gene            33826..35007
                     /locus_tag="KR294_000185"
     CDS             33826..35007
                     /locus_tag="KR294_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH0238303.1"
                     /translation="MKTPRNINSTVVFIIFCLIVTFLLSVILTTITSFNEYNVLSKAL
                     GASYEYNPKSTESILKSLKNSSDKDFKTGNEILSKHGYSKSTFWSKNFFYFLVISFGI
                     ISTMATVIYIIKHRTNKQKLSRINNLTQYLEEVNLGKESVLLRCEDEFSHLEDEIYKT
                     VGELRCSKEFALKERQTLSDNLADIAHQLKTPITSMSLMAQLLSENCPDEEIDYINRL
                     TNQISRLERLVSSLLTLSKLDASTLIFESKLIDVHSLLTYAIEPIEGSLREKHQTFTI
                     EASPSVEFEIDINWTLEALLNILKNCSEHIEDGGYIVAYYSQNPLYVEIIIEDNGKGF
                     AQEELPYIFNRFYRGKNASKDSIGIGLALSKSIIERQNGTLHAENCHNGGARFIIKFY
                     T"
     gene            complement(35188..37848)
                     /locus_tag="KR294_000186"
     CDS             complement(35188..37848)
                     /locus_tag="KR294_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0238304.1"
                     /translation="MNILQEYTLDFVRRNKRSSIAIMLAILLTTTMMSSLCGLLYTMW
                     TDFIRLSIEKEGNWHGELFDYTYGSDLPLIENFSSVDDVMVKGQWYVGKINDEKRDYI
                     IYRNATSEYWNSMPEKDTIIEGRRPNNANEIALSKQYFENNPSVKIGDKITLPIGYRI
                     LNGKPLEPIAPKSKGESFKKISEATLTIVGKVDVSTSSVIPAYTALGYLDKTSIKPND
                     SITVYLRFKNIRDTYKELPKLAKSLGWKTNEYGKYNLKYNSNYLLKMLVFSPEQKASM
                     SSISKFSTPIMYLTIAIFTVAVFVMVIYNAFSLSANARLTQLGILSSVGASPKQIKRS
                     VVFEGFLLTIIPLPIGLFLGWLLCNRLIVYVNSVNYHTDVPEVVFTYGIPAFLPAVLL
                     TIVTVWISALIPARKVSKISPIEAIRQGDSVKIKKSHKYSLGKIFGIEGELASNALRA
                     RKKSYRTATISLTLSFLLLTCFLHIIANQEGAKAVYGSDNYKDQRDIAVYLENSEPIE
                     SAFIEKLDNTEGVKSSLYYQKMSASTWLTEKDASKELAKNGGFKSIVSSKKYSPIERD
                     GKFRIISNIIGLDDKSFTEYCRQISVDPKLFYNTKNPTSIVYNKEEDINRSTRRNKVY
                     IDYLNLSIGDNIKLNEKVYDEDKGDYTYNMKVGAITSTLPKIVDTSSKYTLMQIVPMS
                     MVQEISKNYDEVSRLRSNRLIGVFKVNNREDIPRVREKLESIYNKDYGSGDYSIEDVL
                     ESEKQKASGIKTMNLIVGFITGLLAMIGLSNVLATVSGNIRSRRQEFAMLRSVGLSPE
                     GIKKMLILEGLFLGITPLLLSIPVQIGIVYAFLRINEIYFIEYLPFAPISTIIGFTIL
                     ILFIVIASYMTGYKQLKNENIVESIKNETI"
     gene            complement(37845..38528)
                     /locus_tag="KR294_000187"
     CDS             complement(37845..38528)
                     /locus_tag="KR294_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0238305.1"
                     /translation="MEILKCENLTKIYGSNQTRVTALNNVNLSVQKGDFVSIVGASGS
                     GKSTLLHLLGGVDRPTSGKIYVEDTEISSLKEEALAVFRRRKVGLIYQFYNLIPTLDV
                     RKNILLPMLLDKRKVDEDRFSEIVSILGLSDRLNHLPSQLSGGQQQRVSIARSLIYRP
                     AILLADEPTGNLDRKNSEEIVDLLNLSNKRFNQTILLITHDEKIALEANRIVTMEDGV
                     IVSEKVVKK"
     gene            complement(38872..39825)
                     /gene="blaCDD"
                     /locus_tag="KR294_000188"
     CDS             complement(38872..39825)
                     /gene="blaCDD"
                     /locus_tag="KR294_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDD family class D beta-lactamase"
                     /protein_id="HBH0238306.1"
                     /translation="MKRKKNFIWIAILLVGVVMVMYYVGKKHNDINQKTDKNYIKSEL
                     NKSELNKSKIENNDKNKKEKINMVDYSDCFEGISGGAIFYNTKNKEYNIYNKELIETR
                     RSPCSTFKIVSTLIGLEKGVINSKESVMGYDGTEYPNKNWNKNLSLEEAFKESCVWYY
                     KKLIDKVDAKSVQNILDDLKYGNCDISEWEGDLKNGKGHLNGFWLESSLQISPKEQVQ
                     TMAKIFEGDTNFKKEHINILRDIMKIDINDKNINVYGKTGTGFDEKNKRVDAWFVGML
                     EREGDTYYFAIKSDDSNKEITGPKVKEIAINIIKKYYSVRE"
     gene            complement(40366..42480)
                     /locus_tag="KR294_000189"
     CDS             complement(40366..42480)
                     /locus_tag="KR294_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding domain-containing protein"
                     /protein_id="HBH0238307.1"
                     /translation="MSENKQVVNCDIIASNSKHNMCEYDAELLTFFPDEIAHLIEINN
                     KLDNAFKKAENLVDKLDKDYMDAKMYMVKNRGEIDPHEMFQNEQGLKQIDNYGAFMVK
                     VRDKINKIKDSPYFARIDFRLKDMDDESKYYIGRFAFDYEDELIILDWRSPIASMFYD
                     YEIGKAGYDAPIGWVDGEITRKRQFKIKNGKLEYALESSINIQDDILQKELSHTSDEK
                     MKSIISTIQKEQNQIIRNDKADTLIIQGVAGSGKTSIALHRIAFLLYRFKDKISANNV
                     IILSPNKVFGDYISNVLPELGEEPLCELSFENIAEVQLDRVINFESEKDPLEINDAKW
                     SERVRFKSTLDFVKLIDDYIKQMPNKIFIPKDYTFGSFTAKSDWIQSRFEAYNRYPVK
                     KRLEKVAEDIHYKFESDNIMEEDLPKVKSILKSLNGMLTIKNTLTLYKDFFKQMNISN
                     MFVMATKKTLEWSDVYPFIYIHAAYEGIQEDKIIRHVVIDEMQDYTPIQYAVINLLFK
                     CKKTILGDFGQLVNPNHTHTLDDMKQLYNDGELVMLNKSYRSTFEIINFAKKIQDISS
                     LEPIERHGEEPALLKCNNEQDEINKIKIEIEEFKKSDNATLGIILKTDNDAKAVYDAL
                     REKYSVHLISSESSSFTKGVSITSIKMSKGLEFDEVIVPSVNNKTYYSDYDRSLLYIA
                     CTRAMHKLKLTYTGELTQLIDM"
     gene            complement(42564..43400)
                     /locus_tag="KR294_000190"
     CDS             complement(42564..43400)
                     /locus_tag="KR294_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0238308.1"
                     /translation="MSYKVINVITAIDYIEEHLSEKLDLDIVANAVHYSKYHLHRTFT
                     TSVGLTMHDYIKRRKLTEAAKLLVFSKKPIIEIALIAGYESQQAFTSIFKAMYKKSPN
                     KYRKEQEFYPLQLRFVLKKDNLFSKNVLELEKEIKLASMSDIPLWMNLVRLVIDGFPN
                     LQQEEYIYQLEQYILEERALILKLNNVAIANMVFNRETRSIDFFGIHPQYRNSDIAQV
                     FLKKVIEDFLIDTDISITTFREGDKADTGHRDMIKKLGFAEAELLVEFGYPTQKFILP
                     LS"
     gene            complement(43995..44357)
                     /locus_tag="KR294_000191"
     CDS             complement(43995..44357)
                     /locus_tag="KR294_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBH0238309.1"
                     /translation="MKIYDILTRFYIQDIEKAIPFYENLLKEKCSLRFSYKEVGLELA
                     QIGNVLLLSGSDDALKPFIETKSTFMVDSVDEWRSYLLDNGAVVVRDKKKVPTGYNMT
                     LRHPDGTIIEYVQHTKQD"
     gene            complement(44591..45055)
                     /locus_tag="KR294_000192"
     CDS             complement(44591..45055)
                     /locus_tag="KR294_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HBH0238310.1"
                     /translation="MTRISNITIAEQSEYCFLAIRKTIDFMVEFSEFSKQSFEKISKY
                     LEERGILSSGAPIVCFHNMDLVKLDVEVGFPVATYIDGKNEILQKIVPAQKIITAIDL
                     GPYELQDPTLEDLFSWANSNGYKLHGDIYYQYLNDINRPASEYLTKMMLPII"
     gene            complement(45319..46740)
                     /gene="nhaC"
                     /locus_tag="KR294_000193"
     CDS             complement(45319..46740)
                     /gene="nhaC"
                     /locus_tag="KR294_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HBH0238311.1"
                     /translation="MKERECRKASLFDAMIPITCLILFLSLGVLVYGSSPHVPLIGAA
                     AVAGLVAVYRLGFKWKELELSMFNSIKMAMQAILIIIIIGVLIGTWIVSGVVPCMIYW
                     GLKILSPNIFLVASTLVCAIVSLATGSSWSTMGTVGVALLGIGQSLGMPIGLIVGSII
                     SGAYFGDKLSPLSETTNLAPAMAGTDLFTHIKYMLYSTIPSLLICLVIYGVIGMKYSG
                     QALDIKQIELIRSTLDSTFNTLSPVLLLAPAIVIGLVVFKVPAIPGLIVGAVLGVLFA
                     VVFQGESMNTILDAAQNGYVSSTQIQEVDALLSKGGIMNMMSTVSLTICALSLGGILE
                     KTGMLEVVASSLLRLAKGVFGTVLCTMVTCTITNIIAGEQYLSIVIPGRMYNKEYKKR
                     GIHPKMLSRALEDSGTLTSPLVPWNTCGAYITATLGVSALTYGPYALLNIINPIVSLV
                     LIACKFKISRIEDEPETCLNFDV"
     gene            complement(46770..47834)
                     /locus_tag="KR294_000194"
     CDS             complement(46770..47834)
                     /locus_tag="KR294_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine/ornithine racemase family PLP-dependent
                     enzyme"
                     /protein_id="HBH0238312.1"
                     /translation="MYPRLEIDIEKLKHNVKLISQMCHERNIKISFVTKSFCAQKEIV
                     EEICSEGIDHIADSRIQNLKNLQDINLPKILIRIPMLSELEEVINYCDISFNSELGTI
                     KKLNELCESKNIIHKIVLMFDLGDLREGYFYEEDFFNNVREIVRLKNIEIIGIATNLT
                     CYGAIIPSRENIGRLVSIAKRMEEKFGINLEIVSGGNSSSIHLLINNNMPEGITNLRI
                     GESILLGRETAYGENINGTYQDAFKLICQVVECKEKPSVPIGEIGVDAFRNKPVYEDK
                     GILKRAIIAIGKQDINIDSLIPIDTDIKILGASSDHMILDVSNTKYDYKLGDNLEFLL
                     TYGGIMSSSTSKYVSKKIIV"
     gene            complement(47819..49228)
                     /locus_tag="KR294_000195"
     CDS             complement(47819..49228)
                     /locus_tag="KR294_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate mutase L"
                     /protein_id="HBH0238313.1"
                     /translation="MENSKVSLKIDVLVAEIGSTTTVVNAFHDINTNNPIFLGQGQAP
                     TTVFEGGDVRNGLSGAIKDLANKLSVDDIEYNDMFATSSAAGGLKMTVHGLVYDMTVK
                     AAKEAALGAGAVIRQITSGRIKRTDLNKIKEINPNIILIAGGVDYGERDTAIYNAEMI
                     ASMNLGIPVIYAGNVENQEEIRLIFEDTNYKLYITENVYPKIDLLNIEPTRRIIQSVF
                     EEHITTAPGMKYIKEMVNENITPTPGAVMEASKLLYKNIGDLLTLDVGGATTDVHSVT
                     DGSDYINKILVNPEPTAKRSVEGDLGVYVNMKNIVEVIGKENLQSELSIDIDAVIENY
                     PPIPKSKEEILFVERLTKEAVVKAMLRHSGKIRNIYGTTGKVKIAEGKDLTEVRYIVG
                     TGGALTRLPSRIEILDNMLKYNKNNELLFPKEKTKILIDNDYIMASMGVLSKKYEEAS
                     LKLLLKSLNFEEERLCILG"
     gene            complement(49228..51432)
                     /locus_tag="KR294_000196"
     CDS             complement(49228..51432)
                     /locus_tag="KR294_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892628.1"
                     /note="Presence of a B(12) (cobalamin)-binding domain
                     implies dependence on cobalamin itself, in one of its
                     several forms, or in some unusual lineages, dependence on
                     a cobalamin-like analog; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin-dependent protein"
                     /protein_id="HBH0238314.1"
                     /translation="MLKENKKLDIDYILKDLDKYKPKRRGWVWREHLENLEMGPFKYK
                     DCTKPLKKSVGLPSSKYFNNIDPQPSPVITTEIASGRFEDDIRRMRMAAHHGADHLMV
                     IRTAGQSHFDGLIEGTPQGIGGVPITRKQVRAQRKALDFIEEEVGRPINYHSYVSGVA
                     GPEVAVMFAEEGVNGAHQDPQYNVLYRNINMVRSFVDACEAKKIMAFANIAQIDGAHN
                     ANATAREAWKVMPELMVQHALNSIFSEKIGIDKSNICLSTVPPTAPPAPCLKIDLPYA
                     VALRELFSDYKMRAQMNTKYMESSTREATVTHVLNLLTSVLTRADIQSTITPDEGRNV
                     PWHIYNIEACDTAKQALVGMDGLMDMIELKDVGELRDKARELKERAVLYMEEISEVGG
                     YFESVEQGFFVDSGNYPERNGDGISRKIKGGVGEGTVYEREEDYLAPVTAHFGYNNVA
                     QYDENAIDNPSMLIDGCTFENPDKIIYIDELDDFDNVENRLKESYEYRNGTKIKPEME
                     WCADGIVMITMMIPTDKRTAEFAALEFVKKMNLQEIEVISREVMHESEGTRIEVKGRV
                     PFDIDLNNLVIPEEPKVLTDEEIRADIEEKPMKIVSATVGEDEHSVGLREIIDIKHGG
                     IEKYGIECHYLGTSVPVEKLVDAAIELNADAILASTIISHDDIHYKNMKKLHDYCVEK
                     GIRDKVMIACGGTQVTPEIAVEQGIDAGFGRNSKGIHVATFLVEKRREMSNK"
     gene            complement(51426..51800)
                     /locus_tag="KR294_000197"
     CDS             complement(51426..51800)
                     /locus_tag="KR294_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine aminomutase subunit alpha"
                     /protein_id="HBH0238315.1"
                     /translation="MKKREDDFEVRRKHLQELSDDELKERFWSLATQIVEPMIELGKK
                     NTTPSIERSVLLRMGFSSLEVKPILEGVMERGLIGKGAGHVVYKLAKSKNITVREAGL
                     LLVKGEYWDEVTCLFREGVESC"
     gene            complement(51878..53308)
                     /locus_tag="KR294_000198"
     CDS             complement(51878..53308)
                     /locus_tag="KR294_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent lyase/thiolase"
                     /protein_id="HBH0238316.1"
                     /translation="MNNSTSMKDMSYQAVMGRNNEIMKNAIGLDYSSFEQEGIGFDYE
                     KMMSETGYTLQDIEAIQSQYAVGNTPLIELKNLTKLARKCAKEGKGARIFVKDEAMNA
                     SGSFKARRAATAVYHAKQMGYKGVIAATSGNYGAAVASQAAMQGLKCIIVQECYDSNG
                     VGQPEIIEKARKCEAYGAEVVQLTVGPELFYTFLVLLEETGYFNASLYSPFGIAGVET
                     LGYELAIQFREKYKKDPDIVVCTNAGGGNLTGTARGLIKAGSINTKVVGASVDLKGLH
                     MASDNQFNKKSFTTGHTGFGIPYCTWPDRSDVPRSAARPLRYMDRYVLVKQGEVFYTT
                     ELLAQLEGIERGPAGNTSLAAAFSLAQELDEDKAIVVQETEYTGAGKHICPQLTFARE
                     NGIDIKFGNPREEIAGVNLILPERPELLKCVDIDMNKIRKSFIKNCISNNHIDNIDKL
                     SNRDIEFLMEEVKSSRDFVVDVLNNL"
     gene            complement(53301..53609)
                     /locus_tag="KR294_000199"
     CDS             complement(53301..53609)
                     /locus_tag="KR294_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-ketopentanoate thiolase"
                     /protein_id="HBH0238317.1"
                     /translation="MDAKINDWVIIHNIVLTPEERAPQVPEDTKKVSLEMWVKGFIQS
                     DASIGDLVEVKTITGRLVKGNLLKINPYYTHDYGKCIPELLQIGIQAKEILFGGVYNE
                     "
     gene            complement(53730..54797)
                     /locus_tag="KR294_000200"
     CDS             complement(53730..54797)
                     /locus_tag="KR294_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-binding protein"
                     /protein_id="HBH0238318.1"
                     /translation="MRKVRVGIWGFGAMGIGMANMILKKEGIEIVSVCSRSTSGKSMY
                     DVLGIERGERPEVIINKNYEEVFREKSVDVVLLATDSFTKKAFDKINFLLNRKINVIS
                     TAEQMAYPQADDADLAKKMDEVAKENGVSILGTGINPGFVLDLLVLALSGTCEEVTSI
                     KAKRVNDLSPFGKSVMVEQGVGVTREEFIKGVEDKTIAGHVGFVESINMIADGLGWKL
                     DKIEQTKEPIMTTVDRKSKYGEALAGNVAGCRQCGYGYVNGEVLIEMEHPQQIIPEAE
                     GIKTGDYVSIKGIPNIDLQINPEIPGGVGTYAMIVNSIPLIINARPGLKTMLDIPVPR
                     AIMGDIRNQIEVELEEESKAN"
     gene            complement(55053..56426)
                     /locus_tag="KR294_000201"
     CDS             complement(55053..56426)
                     /locus_tag="KR294_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH0238319.1"
                     /translation="MNEILENIDEGVHFVNKDGKTIIYNNSVQKMEKMNRHDILTNSF
                     FDIVNKMKINRSTLLEVLEKREVIKDNIQKYLDKNGKEITAINTTIPIDIKGEFVGAL
                     EISKNMTTIENLLNRNYKKNLVNKVSIRQKKGYEFDDILGESNLIKEAIAKSKKACKS
                     DASVFIYGETGTGKELFSQSIHYGSNRRNYPFIAQNCAALPESLFEGILFGTSKGGFT
                     GAIDRPGLFEQANKGTLLLDEINSMPIMLQAKLLRVLQEGYVRRVGGTKDIPIDVRII
                     ATTNESPKVILNEHKMRKDLYYRLNIIHIKIPPLRDRKEDIPLLCKKFISKYNKKLNK
                     KVVGISDEAIKILKNYDWQGNIRELENIIYCTMSMMEDEVQIETSMINLNDYYTLKEN
                     KESNNYSLNDLEDKTLSKIISEIEEKYIYESLEKASYNITKAASILGMNRQNLQYKIK
                     KYNIKIL"
     gene            complement(57401..57541)
                     /locus_tag="KR294_000202"
     CDS             complement(57401..57541)
                     /locus_tag="KR294_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0238320.1"
                     /translation="MENLMMSIITGVIASYIYDKLKSHSERPTKSGWELNIKFQKSKS
                     SK"
     gene            complement(57799..58959)
                     /locus_tag="KR294_000203"
     CDS             complement(57799..58959)
                     /locus_tag="KR294_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp27"
                     /protein_id="HBH0238321.1"
                     /translation="MKLNKTLLAIGMSVSLLIASCPTSNALSSINSIKGTNKYETAGL
                     IADKQNYDIAILINSENGLSDGLSASGLSGAKNAPILLTKKDTIPSETLKRLEKVKEV
                     YLIGGKNSIGASVQKILSDKKISINRISGTDRIDTSHKVAKEIGSVSAVKKVILTNAF
                     KGEPDAMSVASIAVRDKSPIVLTDGNTTSFATDGLETYAIGGKVSISDKLINETKATR
                     IGGVDRYDTNKQIINKFYNGSKEFYIASGTDLVYSLVGSTIAQKTPIVLVGNGSNKSI
                     LKNASKITAIGNIDDVVIKQCLNITNNVGDSNTGIVKDTNSNNTNKPSNEPSSNNPGL
                     TDKSTVYVTPNGKSYHLTKNCSTLKRSKTINKVTLKQAKSQGKIDPCNVCVK"
     gene            complement(59130..59333)
                     /locus_tag="KR294_000204"
     CDS             complement(59130..59333)
                     /locus_tag="KR294_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4236 domain-containing protein"
                     /protein_id="HBH0238322.1"
                     /translation="MGFNFRKSINLGGGLKLNLGKKSVGISAGVKGARVSVNSKGRKS
                     ATLSIPGTGISYTKTSTKKRKPK"
     gene            complement(59420..60454)
                     /locus_tag="KR294_000205"
     CDS             complement(59420..60454)
                     /locus_tag="KR294_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YHYH domain-containing protein"
                     /protein_id="HBH0238323.1"
                     /translation="MFKKKLIAVAMSITMISVGSFSYAHSGRTDSSGGHRDNKNKSGL
                     GSYHYHCGGYPAHLHNNGGCPYTGGGSSSGTATSVNNEEKQKRSVGEKGYNQGYEDGY
                     KGNYSSSNYSGDYSDTYESKYSEGYEKGKAKLEEEEKEAKETGYNLGLTGAKSNNTYE
                     KEVLKNAYDTGYSTGYNEYKTKKIEEYKAKGIEDSNKDKEKMTFEENIDSKFIDAYNN
                     AYDEIQEQLKNDYTTQGFESAIKGERFDTSTIGNVKYANWFKEGYDNGKVKLPKAKES
                     VYNQGYNEEDFSIPDEMKSIETKLKGVYDEGLEKREEEKSRNATYGVGAGTAAVVAGV
                     VYKKKKRKKI"
     gene            complement(60976..62337)
                     /gene="rlmD"
                     /locus_tag="KR294_000206"
     CDS             complement(60976..62337)
                     /gene="rlmD"
                     /locus_tag="KR294_000206"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HBH0238324.1"
                     /translation="MSVKKKDVIEFEVDKMEFGGTSLSQVGDRVIHMKGGISGQKVRA
                     GVKKVRSKKAEVKMIELLENSPLETEETCKHFRECGGCTLLSVPYEKQLEIKEKQVMD
                     LFLKQDLFGFQFLGIEGSPENKYYRNKMEYTFGDEVKNGPLTLGLHKKGKHIDIQTVE
                     ECMLVDEDFSKILVSSVEFFNEKKLPYYRTMNHKGYLRHLVVRKGIHTNEIIVNIVTS
                     SQEDFDMYEFKDMLLGIDLKAELVGVLHTINDGLADAVQCDELRVLYGRDYIQEEILG
                     LKFKISPFSFFQTNTKGAEVLYSIARDFIGDYNDKVVFDLYSGTGSIGQVMAGAAKKV
                     YGIEIVEEAVVAANENAKLNGLTNCEFIAGDVAKVVKDLKDKPDLIIVDPPRPGIHKD
                     AIRDICGFGAKEIVYISCNPKSLVVDLVDFKGYGYEIKMVKCMDMFPNTPHCETVVKL
                     IRE"
     gene            complement(62364..63086)
                     /locus_tag="KR294_000207"
     CDS             complement(62364..63086)
                     /locus_tag="KR294_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HBH0238325.1"
                     /translation="MAKKQRIDKILSNLGYGSRSEIKKYCKQGSVVVNGSEVSNPGTQ
                     VDTENDEILFNGEEVIYREYIYLMMNKPDGYISATTDKYDPTVLDLIDLSYLAFEPFP
                     VGRLDKDTEGLLVLTNDGKLSHRVLSPKKHVPKTYYAKIDGVVTEEDVEAFLEGVVLD
                     DGYKTMPSQLNILKSDDESEIELTIHEGKFHQVKRMFESVGKKVVYLKRLSMGNLKLD
                     ESLELGEYRELTDEEVKLIEER"
     gene            complement(63086..63415)
                     /locus_tag="KR294_000208"
     CDS             complement(63086..63415)
                     /locus_tag="KR294_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1904 domain-containing protein"
                     /protein_id="HBH0238326.1"
                     /translation="MPQIKIRGINENDICKISEKMINDLVEAVKCPRDYFEIECIKSV
                     AIRDGKIADVYPFVEVAWFDRGQEVQDIVARIITDSIRNNLDVESMDLAFTVFEKEKY
                     YENGEHF"
     gene            63745..64671
                     /gene="fba"
                     /locus_tag="KR294_000209"
     CDS             63745..64671
                     /gene="fba"
                     /locus_tag="KR294_000209"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-1,6-bisphosphate aldolase"
                     /protein_id="HBH0238327.1"
                     /translation="MALITTKEMFKKAYEGGFAIGAFNISDLEQLQGVLKAAKAKNSY
                     VMIQASMSAVKYAGPHTLVEMVKAASDEIGVDVALHLDHGPNMDAIKTCIDAGFSSVM
                     IDGSHFDFEENVRITKEAVEYAHSKGVVVEAELGVLAGTEDDVTSDVHKYTQPAEAVE
                     FVERTGVDSLAIAIGTSHGAFKFKGEAKLRFDILEEIQSKLPGFPIVLHGASAVDQNA
                     VATCNEFGGNIAGAKGVPVDMLRKASSMAVCKINMDTDLRLAMTAAIRKFLAENPKEF
                     DPRKYIGAGRDAIQAVVESKIDDVLGSANSIN"
     gene            complement(64806..66437)
                     /locus_tag="KR294_000210"
     CDS             complement(64806..66437)
                     /locus_tag="KR294_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH0238328.1"
                     /translation="MDNNLIGLIEHVENPAILCKESGEIIYCNHLIDSIFSFLDIKKP
                     RNINELDSNFDKTEILTDSKKKIAFRELRMTAHIYNMKDNNNENNIVYLFEKSLISDK
                     VIEDIIEHIDEVVVVFNKDGVIEKMNTVSDEILPFKRTEVLGRNITDLVRQGLVEEPI
                     ILNMLKVKKKIYRNIVYPDGKLIAYTAVPRWDSKGKLTGGVLTGRDISRVIKLESQIK
                     YSDISEDTEYISQSKIMDNIKKVVKRAAASDSSIFINGESGVGKEIIARTIYKYSSRR
                     DKPFIAINCGAIPNELLESEFFGYEEGSFTGAKKKGKKGLFEEANGGTIFLDEIGELP
                     MQMQKKLLRVIQENTITRIGGSKPIKIDVRYISATNISHEDLRNNLKFRQDLYYRLSV
                     IPVKIPPLRERKEDIVPLVNYFLKLYNEKYNREVEVSPKVIELLEEYSWPGNIRELKN
                     IIERFVVLSAKNVIGEDEFNMLINLDMIDNETDDLSPIVVNGIMNLNDAYKIVDQIMI
                     SKAINKYGSITKAAEVIGIYPSTIHRKIKSGHIHV"
     gene            complement(66920..67957)
                     /locus_tag="KR294_000211"
     CDS             complement(66920..67957)
                     /locus_tag="KR294_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HBH0238329.1"
                     /translation="MNDIKDLSSYKNVWIFAEQREGKIAPVVIELLGEGRKLAKEVDA
                     ELCAILLGKDVDGLAKELITFGADKVYVADDALLEKYTTDAYTKVIKDAIDEIKPEIM
                     LFGATHIGRDLAPRIASRVGTGLTADCTKLEIDPEDKKIKQTRPAFGGNIMATIICPN
                     HRPQMSTVRPGVMDKAEKDETRTGEVIALDYKITQDDIRTTVLETVKTKKDLVSLTDA
                     NVIVSGGLGLGGPEGFEMLKKLADKLGGVVGSSRAAVDAGWIDHSHQVGQTGTTVKPN
                     LYIACGISGAIQHLAGMQSSDFIIAINKNPAAPILEIADYGVVGDLHEIVPMLIEKLD
                     SVDDLLEAIKA"
     gene            complement(67976..68761)
                     /locus_tag="KR294_000212"
     CDS             complement(67976..68761)
                     /locus_tag="KR294_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012703997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HBH0238330.1"
                     /translation="MKILVCVKQVPDTNEVRINKETGTLIRDGVPSILNPDDANALEE
                     ALKIKDEHDDVTITVITMGPPQADFMLRECLAMGADDAILLSDRAFGGADTWATSNTI
                     AAGISKVGDYDIIFAGRQAIDGDTAQVGPQIAEKLDIPQVTYVQDFKIEGKDIIVQRQ
                     LEDGYELIKVSTPVLLTAVKELNTPRYMSVDKIVKAYKHDVKVWTIDDLDVNKEEVGL
                     KASPTKVFRSFTPEPRGKGEILEGKADEIASKIIIGLKQKHII"
     gene            complement(68794..69927)
                     /locus_tag="KR294_000213"
     CDS             complement(68794..69927)
                     /locus_tag="KR294_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003483287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="HBH0238331.1"
                     /translation="MLYNKEQELLRKAVRDFVSKELDTLPAEMDKTGVMPKELIKKLA
                     DAKFISSNIPEEYGGGGAGYVSYAIVMEEIARRCASTATFVTAGSSLASLPILYNGTE
                     EQKQKYLKGIATGELIGAFGLTEPGAGSDAGGQQTTAELVGDHYILNGRKTFITNGPF
                     CDVAIVIAVTDRSKGLRGTSAFIVESKWDGFSTGAHEDKMGIRGTETSDLIFENVKVP
                     KENLLGKEGQGFKIAMGTLEVGRIGVAALALGIAQGALDEAVKYTKQRVQFGKPIAKF
                     QNTQFTIADMETKVCAARGLVYDAAQKRDAGMRVAQESAMAKYYASEIANEVAYKALQ
                     LHGGYGFIKDYEIERMYRDARIVSIYEGTSEVQKMVISSNVLK"
     gene            complement(69975..71102)
                     /gene="hadC"
                     /locus_tag="KR294_000214"
     CDS             complement(69975..71102)
                     /gene="hadC"
                     /locus_tag="KR294_000214"
                     /EC_number="4.2.1.157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(R)-2-hydroxyisocaproyl-CoA dehydratase subunit
                     beta"
                     /protein_id="HBH0238332.1"
                     /translation="MEAILSKMKEVVENPNAAVKKYKSETGKKAIGCFPVYCPEEIIH
                     AAGMLPVGIWGGQTELDLAKQYFPAFACSIMQSCLEYGLKGAYDELSGVIIPGMCDTL
                     ICLGQNWKSAVPHIKYISLVHPQNRKLEAGVKYLISEYKGVKRELEEICGYEIEEAKI
                     HESIEVYNEHRKTMRDFVEVAYKHSNTIKPSIRSLVIKSGFFMRKEEHTELVKDLIAK
                     LNAMPEEVCSGKKVLLTGILADSKDILDILEDNNISVVADDLAQETRQFRTDVPAGDD
                     ALERLARQWSNIEGCSLAYDPKKKRGSLIVDEVKKKDIDGVIFCMMKFCDPEEYDYPL
                     VRKDIEDSGIPTLYVEIDQQTQNNEQARTRIQTFAEMMSLA"
     gene            complement(71102..72328)
                     /gene="hadB"
                     /locus_tag="KR294_000215"
     CDS             complement(71102..72328)
                     /gene="hadB"
                     /locus_tag="KR294_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(R)-2-hydroxyisocaproyl-CoA dehydratase subunit
                     HadB"
                     /protein_id="HBH0238333.1"
                     /translation="MSEKKEARVVINDLLAEQYANAFKAKEEGRPVGWSTSVFPQELA
                     EVFDLNVLYPENQAAGVAAKKGSLELCEIAESKGYSIDLCAYARTNFGLLENGGCEAL
                     DMPAPDFLLCCNNICNQVIKWYENISRELDIPLIMIDTTFNNEDEVTQSRIDYIKAQF
                     EEAIKQLEIISGKKFDPKKFEEVMKISAENGRLWKYSMSLPADSSPSPMNGFDLFTYM
                     AVIVCARGKKETTEAFKLLIEELEDNMKTGKSSFRGEEKYRIMMEGIPCWPYIGYKMK
                     TLAKFGVNMTGSVYPHAWALQYEVNDLDGMAVAYSTMFNNVNLDRMTKYRVDSLVEGK
                     CDGAFYHMNRSCKLMSLIQYEMQRRAAEETGLPYAGFDGDQADPRAFTNAQFETRIQG
                     LVEVMEERKKLNRGEI"
     gene            complement(72343..73143)
                     /gene="hadI"
                     /locus_tag="KR294_000216"
     CDS             complement(72343..73143)
                     /gene="hadI"
                     /locus_tag="KR294_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyisocaproyl-CoA dehydratase activator
                     HadI"
                     /protein_id="HBH0238334.1"
                     /translation="MYTMGLDIGSTASKGVILKNGEDIVASETISSGTGTTGPSRVLE
                     KLYGKTGLAREDIKKVVVTGYGRMNYSDADKQISELSCHARGVNFIIPETRTIIDIGG
                     QDAKVLKLDNNGRLLNFLMNDKCAAGTGRFLDVMAKIIEVDVSELGSISMNSQNEVSI
                     SSTCTVFAESEVISHLSENAKIEDIVAGIHTSVAKRVSSLVKRIGVQRNVVMVGGVAR
                     NSGIVRAMAREINTEIIVPDIPQLTGALGAALYAFDEAKESQKEVKNI"
     gene            complement(73182..74381)
                     /gene="hadA"
                     /locus_tag="KR294_000217"
     CDS             complement(73182..74381)
                     /gene="hadA"
                     /locus_tag="KR294_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isocaprenoyl-CoA:2-hydroxyisocaproate
                     CoA-transferase HadA"
                     /protein_id="HBH0238335.1"
                     /translation="MLLEGVKVVELSSFIAAPCCAKMLGDWGAEVIKIEPIEGDGIRV
                     MGGTFKSPASDDENPMFELENGNKKGVSINVKSKEGVEILHKLLSEADIFVTNVRVQA
                     LEKMGIAYDQIKDKYPGLIFSQILGYGEKGPLKDKPGFDYTAYFARGGVSQSVMEKGT
                     SPANTAAGFGDHYAGLALAAGSLAALHKKAQTGKGERVTVSLFHTAIYGMGTMITTAQ
                     YGNEMPLSRENPNSPLMTTYKCKDGRWIQLALIQYNKWLGKFCKVINREYILEDDRYN
                     NIDSMVNHVEDLVKIVGEAMLEKTLDEWSALLEEADLPFEKIQSCEDLLDDEQAWAND
                     FLFKKTYDSGNTGVLVNTPVMFRNEGIKEYTPAPKVGQHTVEVLKSLGYDEEKINNFK
                     DSKVVRY"
     gene            75058..76056
                     /locus_tag="KR294_000218"
     CDS             75058..76056
                     /locus_tag="KR294_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-2-hydroxyacid dehydrogenase"
                     /protein_id="HBH0238336.1"
                     /translation="MKILVFGARDYEEPVIKKWSEEHKDVQVDIYPENMTEENVVKAK
                     GYDGISIQQTNYIDNPYIYETLKDAGVKVIASRTAGVDMIHFDLVNENGLIVTNVPSY
                     SPNAIAELAVTQAMNLLRKTPLVKKKVCEGDYRWIAELLGTEVRSITVGVIGTGKIGA
                     TSAKLFKGLGANVIAFDQYPNSDLNDILTYKDSLEDLLKEADLITLHTPLLEGTKHMI
                     NKDTLAIMKDGAYIVNTGRGGLINTGDLIEALESGKIRAAALDTFETEGLFLNKKMNP
                     GELTDPEINKLLSMEQVIFTHHLGFFTSTAIENIVYSSLSSAVEVIKTGTATNRVN"
     gene            76417..76944
                     /locus_tag="KR294_000219"
     CDS             76417..76944
                     /locus_tag="KR294_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04002 family protein"
                     /protein_id="HBH0238337.1"
                     /translation="MEKMNKVTSKKTTYIVTSALFASIICLTIAYILHIPVGGNNGYV
                     HIGDAFIYLAATILPTNYAIAASAIGAGLADLSTGAAIWVIPTIIIKPILVLFFTSKS
                     DKIINKRNIVASVVAGIVGLVLYMFAEGIIIGSFTSAFVMSLLGLLQPIGSFIVFIIL
                     GMALDKLDFKKRYFN"
     gene            76971..77567
                     /locus_tag="KR294_000220"
     CDS             76971..77567
                     /locus_tag="KR294_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04100 family radical SAM protein"
                     /protein_id="HBH0238338.1"
                     /translation="MNILYTIENSIYVNITNTCPCSCVFCIRNEKDEVANSGSLWLEH
                     EPSVDEVKEAFNKYNLDDYDEIVFCGYGEPLMRINELIEVAKFIKEKSSIKIRINTNG
                     LSDLIHNKKTAILLKNVIDAVSISLNAPNKEAYNRVTQPKFGEKSFDYMLDFARDCKK
                     YIKEVAFSVVDEISPEEIEESKQLAKKLDIPLRVRHKN"
     gene            complement(77632..79215)
                     /gene="asnB"
                     /locus_tag="KR294_000221"
     CDS             complement(77632..79215)
                     /gene="asnB"
                     /locus_tag="KR294_000221"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HBH0238339.1"
                     /translation="MINLEEKYLTRKDTYMIKILEYNGHIRNWKVLCEELGIDSSLCR
                     DERERAILVEAYKTWGYDMANHMHGMFAFALWDTVEKKLFCLRDQFGVKPFYYYETEN
                     GKLLYGSSIRKIMEQPGFVKELNEDMLQIYMSFTYVAGENTFFRGVKKLMPGHYLVYQ
                     NKTVCIGRYWKPEFHPDHSKSIEEWTDEIHTTLQKIMPEVKSENETAELFLSGGVDSS
                     YILAMSDIEKTGSCGYEEERFDESKLAQQTANILGCKNSRYIITPEEYFASVPYVMYH
                     MEQPTGDASAIVFAIGCKAAAENTNICYSGEGADEFFGGYNIYHKAECYGENLKTFYI
                     GNTNIMNEGEKRKILKKYNPDVLPIEVVKGIYEETEELDTLTNMSNVDIQIWLEGDIY
                     FNIDKMSTAVGLEVRMPLTDTRIFDIASRIPSEYKVKGKENKIAFRTAASKTLPEEIA
                     FRNKLGFIVPIRIWMADDQYNKDIRDKFNSEIADKFFNIDEINEIFNDYISGNSDNWR
                     KIWMIYTFLVWYEIYFVKC"
     gene            complement(79781..80617)
                     /locus_tag="KR294_000222"
     CDS             complement(79781..80617)
                     /locus_tag="KR294_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBH0238340.1"
                     /translation="MNYIIKKVLNSSVVLVHDTKDNEFILLGKGIGYGKKTGEYICGS
                     NDNQMFVPVENTKSKQFLELMDDIPVDILKITQEIIVEAEKLLNSSFNKNLYLILADH
                     FNFAIERMRKGIKITNRVFWEIKNYYPNEFKVGMVAIYMVEERLGIQLPEEEAANIAF
                     HFANAMASDGNSYDTIKYAKVIGEIINIFVFSLNRTLDKKSMHYMRFITHIKFFVERF
                     FSDSMLSSGDDLLFNQMKRSNPKEMLIALKVRDFLEKKYGKKLTNEEIAFLVVHIARV
                     KQ"
     gene            complement(80641..82107)
                     /locus_tag="KR294_000223"
     CDS             complement(80641..82107)
                     /locus_tag="KR294_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000110363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HBH0238341.1"
                     /translation="MRKFPEGFLWGGATAANQFEGGWNLGGKGWSVSDVAKAHFDADV
                     KDYKSNNEITTKDIEEGLAHPEDEVNYPKRHGSDFYHHYKEDIALMAEMGFKTYRMSI
                     AWSRIFPNGDDKEPNEEGLQFYDDVFDELISYGIEPLVTMSHYEPPLNIVLNYDGWYS
                     RQVINMFVRYVETICERYKNKVKYWLTFNEVDSMIRHPYTTGGLVRDRFKDKNFEEVI
                     FQAMHHQFVASALATKICHEIIPNSKVGCMLTKLTYYPYTCRPEDVLATQRKMRSIYA
                     YSDTQVFGEYPVYLLSYFKNNNIQIVKEEHDDEIMKKYPVDFISFSYYMSSCEAADTT
                     GLDITPGNTLLAVKNPYLEMSEWGWQIDSIGLRISLIELYDRYRKPLFIVENGLGAKD
                     ILTEDKKVHDQYRINYLKEHFKCMLDAIIEDGVELWGYTSWGCIDLVSESTKQMSKRY
                     GYIYVDADDYGKGTYNRYKKDSFYWYKKVIESNSIDFK"
     gene            complement(82110..83972)
                     /locus_tag="KR294_000224"
     CDS             complement(82110..83972)
                     /locus_tag="KR294_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBH0238342.1"
                     /translation="MNYKKTAIDIIEQVGGSKNILALEHCSTRLRFKLIDRSKVNQDA
                     LKKVQGVMSIVNGAQFQVVIGNSVVDVYDEILKVCPLDTNDSTVKTEEKINLGTRFIE
                     FIINIFQPLIFAIAGAGILKSLLMLLAMFNILKSDSTIYTLLVAISDATFYFLPLMVA
                     VTTANVLKCNRLVAIAAVGYLLLPATTTALSEGVELFGFTIPNIAYNAQVFPAILCVS
                     FLATMEKIFNKYSPKPIRTFFVPMMSLAITVPITLTILGPLGYNVGTIFTTIILFLYN
                     KMGFLVVGLLAAFLPFMVATGMHKALIPYSINTIGKLGYEALYMTSSLAHNISESGAC
                     FAVALRTKDETLKQTALSAGISALMGITEPALYGITLQHKRAMLGVVFSSAISGTFLG
                     LFAVKGFVIVGPGLASMSMFIDPNNGNNLIFASIGFVIAILGSFIITLIIWKEDTNTV
                     ESSIGDVVEEELEEEKEVNILVTPVEGKVIDLSKVNDELFASKTLGDGVAIIPTNGNL
                     YAPCDSEVVMLFETKHAIGLRTKNGAEILIHIGINTVSMNGDGFKTFVKTGDNVKEGD
                     LLIQFDLDKISHANLDSTVMIVNNNGADYAYKVLNQSYGNVKKGSILFDVKGGI"
     gene            complement(84219..85082)
                     /locus_tag="KR294_000225"
     CDS             complement(84219..85082)
                     /locus_tag="KR294_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HBH0238343.1"
                     /translation="MILSYFALLIRVVLLAFERVVVRLLGDEEGDIYKNIASSFLFFF
                     IGGVCLLPFSIMDRVSDWSFLIPCYISSLVYSIGSVAYVTSLATGEVSLVTPINSLNS
                     LFLLLLSVIFLGEGLSLAKVAGIIIMIGGVFILKKVSSFLKNVSVIFNNLPCRLMFLY
                     IFLQSVGRVLDKAFFVQVSPILYSTILYFFVGLNLFIFLAFKKKQKIICEIFSNKKGL
                     SILSGAINGYSYLALLIALNNLELSIAEPFSQVSMIITLILAHFIFKENIKEKIPGSI
                     LILIGGWLLLL"
     gene            complement(85137..86069)
                     /locus_tag="KR294_000226"
     CDS             complement(85137..86069)
                     /locus_tag="KR294_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacyl-tRNA deacylase"
                     /protein_id="HBH0238344.1"
                     /translation="MNNKKAVFFFCSDLKKDPVASNVIKCCEEIMDLNQTDIVIDDNF
                     VLEFKDKNNNLFHFVKTKDVISHNYKYYLPILNRHFRDYDFAGVVNWHEGENAPEHIL
                     TAHTIGDVPTGEFGNSNPRYFKNLINAIEDIKNENLLDEFTTLTEATHWSGTTYGEES
                     KLITEYSVPMLDIEIGSSSDSFNNSIAIQVLAKSLIRVFDCDEPLKTLLCVGGVHFEK
                     SFSDIIKNKEYNISIGHVLPNQWIVSGMYDDESGFEKLEKCINSIEGGIDCIVFHDKL
                     KGTYKEQCRKLGEKLNVPVFKHKILKNPKDLPIW"
     gene            complement(86155..86706)
                     /locus_tag="KR294_000227"
     CDS             complement(86155..86706)
                     /locus_tag="KR294_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH0238345.1"
                     /translation="MQSLNEIIAENLKKIRKEKHLSLDKIAQLSGVSKSMLSQIEKCE
                     VNPTISTLKKITNGLKISFTSLMERQESDIELIQKSDIDHFIEDNGKYISYPIFPFDS
                     KRRFEIFMIEIEEGGNLDSNAELPGTQEFITVFSGEVTIKINGEDYIVSSGNSIRFKA
                     DVSHIYRNSGKGIAKMSMVVYYI"
     gene            complement(86935..87426)
                     /locus_tag="KR294_000228"
     CDS             complement(86935..87426)
                     /locus_tag="KR294_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0238346.1"
                     /translation="MIDLKIENRKGKIHVKSSEIKDILELRPDFEYVQDISNTINQEN
                     ILVFDCQLTGNSFDMDDLDIEEILEELGEEIDESYFSVLFEDVRAYLKDATDEIEADL
                     QDNYLFDNLRCYFDIYNINQEFTDFKFVFLVSFKDIKISSLANLAKIVSKRQLIGASK
                     FYS"
     gene            complement(87454..88014)
                     /locus_tag="KR294_000229"
     CDS             complement(87454..88014)
                     /locus_tag="KR294_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HBH0238347.1"
                     /translation="MNKLNICIDIDGTITSPYHFLPYLNDIFNKNITEAECITHNWEE
                     LYGSGIRDVYAEFNNKYIHSYDEAKIVEGATEVISTLSKGHNLSFVTARHECLTDVTK
                     NWLSRQGFSDIDVYLLGSDYKVEKARELSCDIFIEDNPLNSVQLADDGVKVILLDTNY
                     NKDVKHQNIVRVSNWIDIEKIIKQGI"
     gene            complement(88166..89323)
                     /locus_tag="KR294_000230"
     CDS             complement(88166..89323)
                     /locus_tag="KR294_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HBH0238348.1"
                     /translation="MNKQSIGKLNMFFMGITQRNLDNRDFFIELEVIFKSGRKEFKGI
                     AIEEDNKYKFNFKGKSDLYTFNELLKNISKEAENYDGLVFKYVERGTIVVIEGDNKKV
                     NVKYLDNKEEVPKIDEFTASQIKNRDYYVKVGQANALLKEIGVLTKDGKIKNDKIRKY
                     NQIDHFVELIDSILKEIKDKDCITILDCACGKSYLSFVLNFYIKEVLKKNCYFIGIDY
                     SDVVIEASKNMAKNLGYKNMSFIKEDLTNYTPNRDVDLVISLHACDTATDMAIGLGIR
                     AKSEAIVVVPCCHKELLGQYRYEAMEPILKHGVFKARFADLITDGLRTLLLEGNGYDT
                     SVVEYISPLDTPKNLMIRAIKTKTNNDKALKEYKELKSQFGVEPTLEKLIY"
     gene            complement(89360..90301)
                     /locus_tag="KR294_000231"
     CDS             complement(89360..90301)
                     /locus_tag="KR294_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0238349.1"
                     /translation="MRWILVFIFLYLIPLVVIFRNYKNFKRSCIYSSIYVVLATTIMI
                     SNIYMSGLNKIKESMYYHNYISDETYDEKYVSNFKEKESTDLNQDNKKNEEISNNKNL
                     NNKQDRNIQNKESNEEGSNDIKEKNNSDSNVSVNNKSEKQEDNTKENNKYTSKEKNSE
                     DIKKIDMESIGIFKKEIYNIERAALVPMRECIPYTKDIAKNITKLSSIKKDVTNARNK
                     CKEVVKEYENMQIPELSKEKYTETLSNARDDVKKAYELREKSMESALKLINTKSPKYI
                     GKITEYLDLSDKQIESFKNRLNDLKEEINNSETNNIN"
     gene            complement(90388..91080)
                     /locus_tag="KR294_000232"
     CDS             complement(90388..91080)
                     /locus_tag="KR294_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBH0238350.1"
                     /translation="MSLYAIGDLHFSTSVNKPMNIFGSNWDGHEKKIIDNWKEVVKEE
                     DMVLVLGDTSWGINLSEAKKDLDIISKLPGQKILIKGNHDYWWTTVTSLNKLYEDMRF
                     IQTNFYEYKDYAICGGRGWICPNDVKFDETDEKVYKREEHRLRLSLESARKSGHSKII
                     VITHYPPTNDKLEESLFTKLFEEYNVEKVIYGHLHGKESFKMGLKGIRNGVEYTLASC
                     DYTEFNLIKVHD"
     gene            complement(91189..92001)
                     /locus_tag="KR294_000233"
     CDS             complement(91189..92001)
                     /locus_tag="KR294_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HBH0238351.1"
                     /translation="MEYEKWNEILAPYEHAVEELKIKFKNIRKEYLAKGEYSPIEFVT
                     GRTKKISSIISKLKRINAKDIETEIDDIAGIRIMCQFVEDIYAIVDLIKVRNDMTIIG
                     EKDYITNYKDSGYRSYHVIIKYPINSIAGSKEIICEIQIRTLAMNFWATIEHSLKYKY
                     DHYIPETLAERLRRASDAAFLLDQEMSEIREDIMKAQAMYQMKSIAIRDTLNRIQELY
                     DLGDTHKAMQYQRKLDRTETDKNITEILELKQEIDILLEQYKDTKVDDKVVQ"
     gene            complement(92052..92963)
                     /locus_tag="KR294_000234"
     CDS             complement(92052..92963)
                     /locus_tag="KR294_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBH0238352.1"
                     /translation="MNLTKVKGNTFFIKGGTNTGIYVFEDNTALMIDPGLCGSRPRRV
                     NKVLDENNIQVRYIINTHGHDDHYGACNQFKEYYKDVCIMSSEYDKLYIENPELFSKY
                     IVGGKSNVFMDNILKNKMLDDIKIDKFIEAGKFELNNEMFDIIEFQGHTPGSIAVLTK
                     DNVIFVGDLLIGDEILSKYDFLFLYDIQEQINSLEKLKNIDFEYLVLGHGKQVISKED
                     SYKLIEKHLNALKKYLYQIRELLVEPKSLEILLKNIINNNNLSNNYKEYHFFKSSLVS
                     VISYLVDLEEIGYILENGELLYYTKTK"
     gene            complement(93022..93753)
                     /locus_tag="KR294_000235"
     CDS             complement(93022..93753)
                     /locus_tag="KR294_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkgJ family cysteine cluster protein"
                     /protein_id="HBH0238353.1"
                     /translation="MTSIKNKDILNCIDYSIKNKLFDKLNDVYKSLPVGNCSGCGNCC
                     MESVGINLIEFLNIFCYLEDRVDLKKSCISKILDYYFEEYTRKNPCPFKDTNNRCLIY
                     EVRPLNCRMFGHWKKEDYNKNLDNVIEKNNNYRELMKKQYGFEINDEVVNYRIDYCDR
                     FIPNKDYLSKSKRLSFFDELMILDSNIYSSGNIDIDFRDRGIVEYFIESLLYRNLAYN
                     VKIRISKEYKIRKRTIDRIKRIVLV"
     gene            93842..94093
                     /locus_tag="KR294_000236"
     CDS             93842..94093
                     /locus_tag="KR294_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0238354.1"
                     /translation="MNRYTKIINMMGSYYTKDFEKEKKNVIKVREVKEDTVRKFFLQG
                     DCEVLVVFEDTGKEILIDDFSPEEDIKKYLGAKFINKKR"
     gene            94327..94746
                     /locus_tag="KR294_000237"
     CDS             94327..94746
                     /locus_tag="KR294_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0238355.1"
                     /translation="MQIYFRVKAVGKRKPMLELTPFDVSDNINCLKEAISEIVSKNVL
                     EYNEKIPEKSIINFLTNEEIESQADIGKVGFGSIYNENKQSVEKAIEVALQAFEDGIY
                     KVLINEDVIEKLDSSINLKSGDIFTFIRLTLLAGRMF"
     gene            94771..99828
                     /locus_tag="KR294_000238"
     CDS             94771..99828
                     /locus_tag="KR294_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4132 domain-containing protein"
                     /protein_id="HBH0238356.1"
                     /translation="MLERTRVEKNPKIIENFKNNFTKSSSKQYYDLAKSLWDCIENSS
                     YYYREPEDKFLNMIKKYYNCHYYEIKNMDELLSGPLKNALELIFTSEQVEELCQLIKR
                     KMDYTYSGGYYRKGYRSNKLVDYFRGIIRFISNYVDLIYYDFSVIDYLTLPNKVLYYD
                     SIMSDKIALEIDKGNQKVISALEEVIFGENQTALLTRQMIIGIMKSHSDKCYEMLSKL
                     LLAAKQQEGLRQQIVESLDEGTISASIYMLKTILDNNLERFSSVIRALDTWTGLGFSD
                     QKPGIIRKCLELSYKSLTDEKFRIESINSNDNLEIYFALWATATYNIYDSYSLIENLL
                     SCQEKYKKLVALYFLSHTESTYFKHSIASKNIKGDDLEILAWVITNFYVEGSVGYYYS
                     WQNRETNFDLSNTPIDKDFDARKEQFESLKHTLEILNSKTKSFSGSVFPWTWIEISSH
                     EILKCMMTLTAYDMNAQFIDVLMENCHLMSSDLRASLIVNFVNEPKTDRQREFLLECL
                     SDKSVSNRETVLSLLRKLELTDVELDKITNLLSLKTSSIRQTVIKILLEQDDSNLENI
                     ASSLIKSSNSQKCLGGLEIVNLLKDNTARQELYNKLVLLIEDIDKSKKNTSQVQILID
                     NLLGKAKNDYCKENGFGIYNPENKVQIPEQFDFKDDSNSSSKLNKIISNISLSTREDS
                     VSVATKKEAKKILDTDINKIIKVYEKFDELITENADYEYEVERWSGNVDKVLLGYSTY
                     NLTPIKYKVSNDTLDNYPLAELWRETSKKLDLDYKLILDILFYSISTCGYNETEKSWF
                     SSIYSNVLDSKKQNKIYTKLEKLKFNGLTRKLLRVLLNEFDHKEIFNYCLEIYYKLRN
                     LLTIEQCKKQRVEFTKNYYRQNEYCPALNAPILNYWLDKAHSFIYDDISFTKFFYTTF
                     SNYQLLEYKFPFYTSINVFARAHELGLMTEEQVNREMISGYNASNIIRTLTNPRWAGD
                     TLEKYPWLKDNLKTVTNRIIEIESRRGDMPTEVSHLANNIQYFEGINYFVNILVALGK
                     ETFQRGYSYGSNYSKKDVLSSLLKNCYPTKEDDSKKLKSLLKNTDITELRLIESAMYA
                     PQWVNIIEKYLNWKGLKSTIWYFHAHINEGFSAQKESEVALFSPISPRSFIDGAFDVD
                     WFLDSYKTIGEERFNILYKSAKYITSGGNSHRRAQLYADATLGKLDKDMLMKEIETNR
                     NQDKLRSFSLLPMKKGDLKEATFRYEFIQKFAKESKQFGAQRRESESKACTIALENLA
                     RSAGFGDVNRMMWALETEKLNEVAHLFKPKDIDGTSIWIDVDENGKASTKVQKGNKSL
                     KSIPKAIAKHPYVLELKSVQKDLKSQYSRAKQSLEQAMKNEIVFTVKEIANIYKNPVI
                     CPLIKNLVWVCDDNIGYVYNDKSKFFICNIEGETYKLTAKNKLKLAHPVHLFESGKWS
                     EFQHDLFSKQIVQPFKQVFREYYRINSDELSEKTISRRYAGHQIQPKKTVALLRNQLW
                     TVDYEEGLQKVFYKENIVAKMFALADWFSPADIEPPTIETVEFFDRKTYKSLELASIP
                     PILFSEVMRDIDLVVSVAHAGGVDPETSHSTVEMRIAIAKELLLLLKINNVNFEGSHA
                     LIAGNLGEYSVHMGSGIVHKKGMGALNILPIHSQSRGKIFLPFADEDPKTAEIMSKIL
                     LLAEDSKIKDPSILSNL"
     gene            complement(100014..100751)
                     /locus_tag="KR294_000239"
     CDS             complement(100014..100751)
                     /locus_tag="KR294_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0238357.1"
                     /translation="MIKVLICDDDKIVRDDIANIAKESGYVDYVKKVKDGIEAIEFIK
                     NEKIDLLIIDIDMPYKNGIDSAEEILSIDKDIHIVFVTGFADYSLESFKVHPIDFVVK
                     PFKKEKILDSINIAIDHINSHKIANNNFIEDTLFVYKIRKQIHMINFDDIVMFEKNSR
                     AINLHTKDEDIIKFYENFDDLKKRLPPNFFMTHRQYIVNLRFIHKVIPINKSSLEIRF
                     INFQENAILNKSLEKDFLYRFYRVKRF"
     gene            complement(100770..101705)
                     /locus_tag="KR294_000240"
     CDS             complement(100770..101705)
                     /locus_tag="KR294_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBH0238358.1"
                     /translation="MANNFVFPIVILTLFIFSNLIMNKYKFYKELDILKRGILTFFIS
                     CFALILFMEGTKYIQLRLGYSFLLEGVLNIILFLVLIILSFYTGFKVIRLINNNNEQE
                     YKLQKLDSKINHKDNIIIKLRSQKHDYLKHLQVVYSLLNTGLDEDAKEYIMNISNSFK
                     SKNSRYGKVSYLDAIASLKYEECLEKDISFDVYIQDFMDNLEIEPNDMSSVLLNIIDN
                     AIESLSTIKKEKKYIRVHAYEDEFQYIIAIKNNGPKIHNVESIFWNGFSTKEGQDRGY
                     GLHLVKNILDKYDYSILVNSDDFLTEFVILIPKYY"
     gene            101913..104489
                     /locus_tag="KR294_000241"
     CDS             101913..104489
                     /locus_tag="KR294_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HBH0238359.1"
                     /translation="MKDNLKIVLRYIKSYKARSLAIVVSIILATSLVVGIGTLSRSAQ
                     QADVDRLKRELGTDHVYFKNIKKNQLKSIKSSKDIKNLGITSYYASTDVNEKLPINIL
                     YANKNYLTSHSKLIKGRFPKASNEVVVEKWILNSMGLKPEINQNLTFKLYQKENPETF
                     KVVGILEDRFIEKKKGQCEIFSNLNESELNDFTTYIEFNEGSDINTNIDNIIKNAMLD
                     EKSIGRNSMLIESTMKNGTLDNSSKYVAIAMSLFAGIVIYSIYVISIYQRVQEYGVLR
                     AIGSTNFRIFKLMLYELFILALIAMPIGICIGMGGAQIFNRSVGNIQFEGNINVTPFV
                     IPDKIILLSIACTILIILIISFFTYLKIRRISPIDAIRKTFGADKNVTKVNYLISKLT
                     LNMSVTKSISAKNIFRNKKGFIIIVLSMSIGGIIVIKDNYKYSFLDVQNKSTQEQTYM
                     NADFILSNVYLNEIGNNTSFKDIKGFNDNQIDKIKNIDGIDKVKTASILNTRIEVNKI
                     NRLDYYEAINSTPYYKLNPLFIKNKTTGKYTLKQKLKGYNDEMIKSLEKYLVSGNINL
                     KKMKKENLAIVYVPEISKTQKYTKTFTPGEGTPAVDIKVGDTIKVKYPKGGMDTGLYE
                     SLKDNYEYLEYEFKVGAIISYPFADNGMYSGDDGVDVITSSEYLKKLTGVDKYNLVYA
                     DLNENANKKKINNLLGKIGSEVPGTTTVDMMVEKENSDKMTSRTMIYSYGIVAIMFII
                     SVLNIINNISYNLTSRTSEFGMLRAIGISERGFKNMILYEGILYGVLSSIITIVSGII
                     IQFKMYYMQGFVSYGLGFSIDYKIYILVILANIIVGILATYIPSRKINKISIVEAINI
                     TE"
     gene            104501..105172
                     /locus_tag="KR294_000242"
     CDS             104501..105172
                     /locus_tag="KR294_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0238360.1"
                     /translation="MPILETINLGKIYGKKETSVHALKNANLKINKGEFVAIIGPSGS
                     GKSTFLHLVGGLERPSNGTIKVDGKDICCLSDKELARYRRQKVGFVFQQYNLIPVLNV
                     KENIELPLKLDNKKIDKEYIDDLINLLGLNERKNHLPNQLSGGQQQRVAIARALSAKP
                     SIILADEPTGNLDSKTTEEVMDLLKSSIKKYNQTLIIITHNENIARKADRIISIIDGE
                     LKLTL"
     gene            105199..105540
                     /locus_tag="KR294_000243"
     CDS             105199..105540
                     /locus_tag="KR294_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0238361.1"
                     /translation="MLLILGNLNLNLDFDYRIIREENDDVDIFIDINYRSLDIDTDGS
                     NLFNSRIQFPFVRALILRLNKNNQCMTIHLLRDIDLFSAFANFEVDYTDSIINIKNQN
                     EKVILNKSIKK"
     gene            complement(105900..108542)
                     /gene="adhE"
                     /locus_tag="KR294_000244"
                     /gene_synonym="adhC"
     CDS             complement(105900..108542)
                     /gene="adhE"
                     /locus_tag="KR294_000244"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HBH0238362.1"
                     /translation="MEKKEKVVEKSNVEVCSPEIVNSVETLRMRLEEIRLAQKEFATF
                     TQEQVDKIFLAASTAANQQRIPLAKMAVEETGMGIVEDKVIKNHFASEYIYNAYKDTK
                     TCGVIEKDEAFGFTRIAEPVGVLSAVIPTTNPTSTAIFKSLIALKTRNGIIFSPHPRA
                     KNCTIEAARVVHDAAVKAGAPKGLIGWVDVPSIELTNVVMAEADLILATGGPGMVKSA
                     YSSGKPAVGVGPGNVPAIIDESADIKMAVSSILVSKSFDNGMICASEQAVIVPEKIYE
                     EVKKEFKYRGAHFLNKEETEKVGKVVIIDGSLNARIVGQPAHVIAKMADVEVPKTARI
                     IIGEVESVELNEPFAHEKLSPVLAMYKSKSFEDAVAKAEKLVADGGYGHTSSLYADSI
                     NHPERVEKFVNAMKTCRVLVNTPSSQGGIGDLYNFKLAPSLTLGCGSWGGNSVSENVG
                     VKHLLNIKTVAERRENMLWFRAPEKVYFKKGCLGVAAREFKDVMDKKKAFIVTDSFLY
                     NNGYTKKLTDLLDEMGIKHTTFFDVAPDPTLACAREGAKAMADFQPDLIIAVGGGSAM
                     DAGKIMWVMYEHPEVDFQDLAMRFMDIRKRVYVFPKMGEKAYFAAIPTSAGTGSEVTP
                     FAVITDQDSGVKYPLADYELMPNMAIIDADMMMEMPPRLTAASGVDALTHALEAYVSM
                     LRTEPADGLALQAGKIIFEYLPRAYKNGKNDKEAREKMAMASTMAGMSFANAFLGICH
                     SLAHKLGAFHHVQHGVANALLINEVIKFNCAEAPNKMGAFSQYRYPDCIQRYAEFASF
                     AGIKGSTDQEKVDNLIKAIDELKAKVGLPKTIKEAGVEESKFLERLDAMVEQAFDDQC
                     TGANPRYPLMSELKEIYLKVYYGK"
BASE COUNT        36657 a        18431 c        12967 g        40919 t
ORIGIN      
        1 attataaaat taccctaatt gccaaacttt ttaatataaa ttttccaaca tcctacaaat
       61 ataatcaata gatatagaat cctaacttac accaatatat atttatttaa aatagtccta
      121 aaatacctgt aatagctccc actactatca gtataaacat tatttttatt ggagaaagac
      181 ctttttttaa agcaaagagt actaataaag taagtaccaa aggaattaac ccaggaaata
      241 tcttatcaag taaatccgtt tgaagactaa atttaaaatc accactagta taacttattg
      301 gtgtagataa attaataaac ctacctacaa gtccccccat gactaaggta cctagtatag
      361 aagccccttc tataacctta tttactattc caccttgaag tatactttca acagcttttt
      421 tcccatactt atatccattt gtccacattc caaaagaaat tgaagtcatt attatatatt
      481 gagctattac aaataatata ggtcctgcaa ttgatgctcc tccctcagtt aaaccaatac
      541 aaacagctaa cactatagga gttataactc cttgagttaa agtatcacca attcccgcta
      601 gtggacccat caagcctgtt ttgatagcat tcataccatc tccacttatt tcatctgctc
      661 cattagcttt ttcttcttcc atagctattg ttattccatg tataacacat ccacatatag
      721 gttctgtgtt aaaaaatgct agatgagtct ccacttcttg ttttaactct tccttatctg
      781 gatataattt tttaagtact ggcaacattg aatgtgaaaa agctgttgat tgcaatcttt
      841 cataattgta attagattgt gcaaagaaaa accatcttaa ccatgatttt attacatctt
      901 tcttgcttaa cattttctta gatacttcat tttttatatc tgacataata ttttccccct
      961 cacatgtatt taagatgtag cactatcttt tccgtactta attgaagtaa ttgtaagagc
     1021 aagtattact ccaataacag atattactat tatatctact ttaaaataaa cagccattag
     1081 tattcctaat atgaaaaagg gcatagtaaa cttgtttcca atcaatttta aattcatagc
     1141 aatcccaagt gctggcaaca tagccccaat tacattaaat acatgtaaca cattatcatt
     1201 cattacttcc aacataccat ctatcgcatt tggaccaaaa taaacaacta ataatgctgg
     1261 tataaaactc attgcaaata acagtatctg tggtggtact atatttataa atgctactct
     1321 atcaacattc cctttttgaa cctctctatc agcccaatgt gcaaaaaaag aatttactgt
     1381 catctttcca atccaaagta cagttgcaac agttcccaat ggtacagcta ttgccattgc
     1441 agtacttaca tctagcttag atgctatagc taaagcagta cctacatatc ctgcaaaagc
     1501 tgggtccccc atctgagctc cccctgctga tataaaacct agatatatca tatttatacc
     1561 tgctcctata attgctcctt gaacagggtc tcctaatata attcctgtta caaatccagc
     1621 caatagaggt ctattccatg taaaaaatcc aacataagtc aaccacggac tccaagaaag
     1681 ataataaaaa attgctatta atactgcttg aattagtgaa atgtgcatat tcttcctccc
     1741 tattttcttt taaagattta caagatagtc ttctttacaa taatgttcct acatcaattt
     1801 tctttgcatc tggtactatt tgtataaagc atttaatatc ttttgatatt agctctctaa
     1861 atatttcttt ttcttcatct gacacagata tatttttata aaaacttttt ctaccaagcc
     1921 ctgctcccat acctccaaca ttcaattcct ttaaatctac cccactattt actaaaccta
     1981 agacagtttt agggtatttg accaatacta ttaaattttc atctccatta tgtgatttta
     2041 agacttcagc acctgattct acattatgta cttcaacctt aacagttgat ggagctgcca
     2101 tttgtaaaac ttgaactata aatgggtcct ttactactaa atcatccacg attactatcc
     2161 tttttgctga tgtaatctta caccaagcag taataacttg cccatgtatt aatctatcat
     2221 caattcttgt taatgctata ttactcataa ctattcctcc agatttttaa tttattttac
     2281 aactttaaaa cagttttaac atctttgatt cctgatatcc caacttcctc acataaattc
     2341 ttcaagtctt ttaacttcat agtatctctg tttaaaaata actctaaaag cataggtaaa
     2401 tttacacctg tcaaacattc taactcacat accttagcaa atttatttat tataatagca
     2461 gatgtattaa atggagttcc gccataaaaa tcaagcaata ctaaaacccc ttcatcctta
     2521 tatttctcaa ttccatcttc taactttcta ctaaactcat ctatgctgtc accatggttt
     2581 aatcctaaag tttctacatt ttcctgtttg cctactatta attcagcact ttctaacatt
     2641 gctttagcca tatttccatg tgtggctata attattcctg ccatatgaat catacctttc
     2701 ttaacctttt ttatatggat tattatttag tactctaatc taattatcta tattaatcat
     2761 tatcttacca aagaaaatat cccttttgta tactttttca aaataagctg gtacttcttc
     2821 taaatttatt ctatgtgtta ctaatttttc aacattcata tcaccctttt gcatatgata
     2881 caatccagca ctccattctt ttcctgggaa tggaaaggag tttccaaacc aagttccctt
     2941 tacagttaat tcacttctta ctatcttttc aaattgctct ctagtcaaag ctacatcccc
     3001 atatggtaca cctgcataca atactgtacc tcccttttta gctagcaaca gtacttgacc
     3061 acatgtcagt ggagtaccag ccgattcaat aacaatatct gcaccatctc catcagttaa
     3121 cctttttatt tcttctacaa tattcttttc ttttgcattt atacaaatat ctgcccctaa
     3181 ctcttttgcc aagtctaact tctcatcaaa tacatccaca gctattactt ttgtagaacc
     3241 aaatattttt gcccattgta ttgaaaataa tcctattgga cctgtaccaa gtactacaac
     3301 tgtatctcca actttagctt ctgacctaaa aagaccatgt cctgctatac atactggttc
     3361 tagtgcagcg gcagtctcat aacttatctc atctggtatt tttattaaat ttctctcttt
     3421 cacctttgta tactctgcaa aacaacctac aagttcttta tttcctatta ttgctacatt
     3481 attacatctt gaatacaagc cttttttaca ttcatcacat tcaaaacatg gcatagctgg
     3541 acaaacagca actctatctc ctattttaaa actccttact tctttaccaa cctgtgccac
     3601 ttctccagaa aattcatgcc ctaaaatttc tccaaccata tgtggacctg tctttgaata
     3661 ttttgatata tcagaaccac atattccagc tacttttact ttaattatta catcatcttt
     3721 ttctaatatt tttggtacat ccacatcctc cactcttgtg tctcttatgc catagaatct
     3781 aactgacttc actattaacc acccctactt tttatttgag aatatatccc tattgtttat
     3841 atgttaaata tctaaagcaa ctttcatgcc aatatatgta agcattgtat tcatgcattt
     3901 tataaaatta tcattaaatg tgtgtcaaag tgtgtcaaaa gtttcttata ttaaaactta
     3961 tgtgtgtcaa tataaacaac actaacattt tatattagtt ctcttattat aagttttata
     4021 aaatgtactt tttttgttat ttttataaaa ttgttcggaa atttcccttc tatttgtgat
     4081 ataatattaa atataaggta tcaatataaa ttttcatgcg aatatcagaa cttttttgac
     4141 actaatgcct tattcaatat aataatttaa ctttttggag gttgtttatg aaaaaagtgt
     4201 atcaaggaaa gactaaagat gtttttgaat tagataatgg aaattactta cttaaattta
     4261 aagacgatgt aactggtaaa gatggagtat ttgacccagg cgaaaatagt gtaggtctaa
     4321 gtatagatgg aattggtaga gctaatttag agacatctgt taagttcttt gaaattctaa
     4381 acaatgctgg aattaaaact cattatgtaa gtgctaattt agaagaagca actatggaag
     4441 ttctaccagc aaaagttttt ggtaatggat tagaagttat ttgtcgttat agagctgtcg
     4501 gtagtttctt acgtcgttat ggttcatgtg ttgaagaagg tgctaaacta gattgttacg
     4561 tagaagcaac tttaaaagat gatgaccgtt gtgaccctct tataacatct gaaggtttag
     4621 aagctttaaa cattatgact caagctcaat ttgattcaat gaaaagcatg actcaaaaaa
     4681 tttctaacat agttcgtgat actatagctg aaaaaggtct tgagctttat gatattaaat
     4741 ttgaatttgg attctacaat gatgaagtaa tcttaataga tgaaatagca tctggaaata
     4801 tgcgtgttta taaagatggt gtaatagttg accctatgga tttaactgct cttttattag
     4861 ataaatagta tatacatata atttacaaat ataataaact tataaataag ataagctatg
     4921 aagtaaagac tttttaaatg ttgattattt ttaaacattt tctcgccttt aatttcatag
     4981 cttatttaaa ttaatatact ctaattagta gataatagct ttaaccctac aattcccacc
     5041 acaataaaac ctatacatgc aattcttgat atactaatag gctcatttaa aatagccatg
     5101 cctacaatag ctgtaccgac ggtaccaatt ccagtccata ttgcatatga agttccaagt
     5161 ggaagatgtt ttagtgctaa tgacaaaaaa taaaaactta caatcattcc aacaacagta
     5221 agtatacttg gagttaattt agaaaatcca tgtgaatttt ttagttgaaa agcccaaaac
     5281 acttcaaaca aacctgcaac aaacaaaaat aaccatttca taaattcatc cctcttttca
     5341 aatatgtctc ttatttttcc aataaaataa cctgagaaat attataaaat atctcccagg
     5401 tttttgtcct tccgtgttca caacaaaaac tatgttgtgg gttttatctc ggaccagacc
     5461 aatcattaat aattgcggaa ccctataaaa ctctattaat tattctattt tatctataat
     5521 aatactatca acatatataa aaaaagtcaa tatatgggtt ccatatataa taaaaataac
     5581 ttttatatac cttttaatat tcttattcac ttctctccat acccatttag gtcaatctaa
     5641 gaatatctaa tttttattta atatgttata ataacataaa aatattgaaa ggagtaattt
     5701 ctatgaattt ctataaaatt gcagtatgtc agatgattac tacagaaaat aaaattgaaa
     5761 atatcaatca tgctgtagat atggtaacag aagctgccat caatggagct aaaattgtag
     5821 ttttgccaga aatgtttaac tgtccatatg aaaataaata ttttcccaaa tttgctgaag
     5881 aatatccagg tgaaacaaca acgatattaa gtaaattagc tgagaaacat ggaatttatc
     5941 tagtttctgg tagtattcct gagttagaag atggaaaaat ctataatact tgctatgtat
     6001 ttgataaaaa tggagctcta attggaaaac atcgtaaaat gcacttattt gacattgaag
     6061 ttacaggaaa agttagtttt aaagaatcag atactcttac agctgggaat gatgtcactg
     6121 taatagatac cgaatatgga aaagttggta tagctatttg ctatgatatt cgtttccctg
     6181 agttatcacg tttaatggcc cttaaaggtg ctgaaatcgt tatcctacct gctgcattta
     6241 atatgactac tggtcccgcc cattgggagt tatctataag aatgcgtgct ttagataatc
     6301 agatattcta tgttggtgct gcacctgcta gaaatatgaa tgcttcttat atagcttttg
     6361 gaaattcaag aatttcagac ccttggggaa gaataattgc tcaagctgat gaaaaagaat
     6421 gtattattta tgctgacatt gatagagatt taattcctga cataagacaa cagttaccac
     6481 ttcttaagca cagaagaact gatttatatg aacttaatac tttgaaataa aacagaacat
     6541 aaccccataa atcataaatt aagtgttaaa aaaatttatg gggttctcat taatttgatt
     6601 taaaattaat ttcataaaaa taatgctaaa attaatttaa ttaaataata ctaataatta
     6661 ctaatgatta tgctaattat cagcatttac taatttaatc actattagtt atttctttta
     6721 ttaaatatct ttactttttt acttattatg tcttctagct ttacatttgg attatggtat
     6781 ttctttctat ttttagtcac atctttctat tgaattactt gcttaaaaca ccaatgcaca
     6841 catgccagat aatgttcaca attatgtaga aatcttgctc taccttcttc aatgttgata
     6901 ttatctctcc tagttgatat tatctttcct aaaatttctt ttaattaaaa aacaacatta
     6961 gttgatatat caagtatatt ttaatcaact gaaaaaaaca ataataattg atatatcaac
     7021 taattaatgt agattaattc atttttataa tttatatact ttttaattaa tctaccttat
     7081 ttaattaaaa tccttccttt ctatttatcc attttcaact taaattataa gatttcatca
     7141 gctatatttt tgcataccaa taagcattaa atatcaaata tatattctat taaaatttct
     7201 aataatttca tccttgattt atttaatata taaaaatata ctaactttaa tgattaagtt
     7261 ttgaaatata actaaaaatt tgataattta ttgagatttt tatactaaaa tatacatact
     7321 atacaaactt aatttagaag ggagcattct tatgaacaat aaaatactcg tcgtagatga
     7381 tgaggaaggt ataataacac tcttaaaaga ttactttgaa atgaatggtt atgaggttta
     7441 cactgctcaa agtggaaaag acgcattaaa aaaaatatcc aaaaatccag atatcattct
     7501 acttgatata aacatgcctg aaatagatgg aattgaagtt tgtaatagaa ttagagatta
     7561 tgtatcatgc cctattctat ttcttacagc tagaattgaa aatactgaca agataaatgg
     7621 ttttcgtgct ggtgctgatg attatattgt aaaacctttt gatttagacg aacttggagc
     7681 tagagtatct gcccatttaa gacgtgaaca aaggaagtca aatcaaacta aaattaaatt
     7741 ttataatgat ttaacaatag attacgaaaa aaggttaatt tgtatatata ataatcagat
     7801 ttcactttca aaaaaggaat ttgatatagt agagcttctc tctatgaatc ctggacaagt
     7861 atttgataaa gaaaaaatat atgatagagt ctggggatac aatagcaatg gaaatagtga
     7921 tgttataatg gaacacatta gaaaaatacg aatcaaacta tcaaaacata ctcttgaaaa
     7981 ttatatagaa acagtctggg gagttggtta taaatggata aaataaataa tatgtcatta
     8041 aaaaaagctt tctttgttct tactttatct tcactaatta tagcatcagt acttactact
     8101 ttcgcataca ttttacttaa taatctatat aattctatac aagataagta tttaaaaaca
     8161 cctataaata caggtattat aaccatagtt caaaacaatg tgaaccaatt tagtgattat
     8221 gataaaacat tacttaatat aatcaacata ctccagcttg tacttccact tatatttttt
     8281 ataggacttt tattattagc tgatataatt ttttacaagg taaaattaaa aacacccata
     8341 gaaatactca ataaaggtgc aatggaaata tccaacaaca atttagactt ttgcttagaa
     8401 tataataata atgatgaatt aggtaatcta tgtaatgctt ttgaaaaaat gaggtctgaa
     8461 ctaaataaaa acaacataaa gatgtggact atgattaatg atagaaaaca acttaatgct
     8521 gctttttctc atgatttaag aaatccccta acagttctaa aaggttactc aaactattta
     8581 acaaaataca taccaacagg taagcttagt gatgagaaga ttttatcaac cacacaactt
     8641 atgtctgagc atattaacag aattgaatac tatgtagaaa atatgagtaa tgctcaacga
     8701 ttagaagatt tagttgtttc aaaatctatg tcgaatataa acaagtttat agaaaactta
     8761 gatgaaaata tatctatcat tgctaaacaa gaaggaaaat cttttacact taaaaatcaa
     8821 ataaataata taaatctatt ttttgatgaa aatatcattc ttagagtcgt cgaaaatata
     8881 atatcgaatg cttttagata tgctagaaat aatgtatcca tacttatata tcttgaacaa
     8941 gaactcctta cctttgtaat tgaagatgat ggtataggat ttagtaagga atctctaaaa
     9001 ttagctttaa gacctttcta tagagataag actttaaatg acagcaatgc acactttggt
     9061 atgggtcttt atatctcaaa aatattatgc gaaaaacatg gtggctctat ttctattgaa
     9121 aataattcta ctaacagtgc taaaattact gctaaattct caacaagaaa ttaaaatgat
     9181 tttgtaagct ttcactgttc ttatataaaa tttgttagtt tagaatttat aaaatgtatt
     9241 tcaatttaca accaatatat atactatttt gtagaagttg taagagttgc ttcaattata
     9301 atatttggca aaaggcattt gaaataataa tagaaatata tatttaaata tgtagaatag
     9361 tatgaaatta gaattttgga ggtgattata ttaaaagttt tgctaataat attacattct
     9421 ctcgtattgt gtttgcattg ctaatgctta gttctacatt ctgttcactg cctttctgga
     9481 tatgttattt ttggtgtgga attagtgata tacttgatgg tcttattgcc cgaaagttga
     9541 gacaacaaag tggaataggt gcaaagttag atagtattgc tgatttcatt tttgcggtta
     9601 caattttggt tactgtcgga aaaaatattg ctcttcccat gtatctatgg tggtgtattg
     9661 ttgcaatagc attgttacgg ttgattagtt acagtattgg tttttttaag tatcgcacat
     9721 tttcatcact tcatactttg atgaataaaa tcactggaat ttctatcttt gcgtttccat
     9781 tactctatat ttgctttggt cttgatgttg caggaattat gatatgtatc gtggcttttc
     9841 tttcttcttt tgaagaaata gcaattatga taaaatcaaa agaattaaat cgtgatataa
     9901 aaagtatatt tatgtgacaa cttagaattt gtgacaaaaa taatttatat aataatgagg
     9961 aagtaaaaca taaaaaatta tccacaagtt tatgtgtaaa atagttttaa aacaatagag
    10021 ttgtattgta aagcctttag tgcataaatt acattttaaa ttaaaaatta tactgaaact
    10081 gcttatcagc actgcgaatt atccgcaaat agtgaagact ttttagattt aagctaaaag
    10141 ttgggaaaaa attgagtttt aaaacttaca ctcttcttat atagaaaagg agagtgtttt
    10201 ttatgattat aaaagcaaaa caattatcaa aaatatatgg ttctaataac aataaagtta
    10261 tcgcacttaa taatgtaaat ttagaaataa actcaggtga atttgtttct gtaattggac
    10321 cttctggaag tggaaaaagc acacttttac atattttaag tggattagat aatcctacct
    10381 ctggacaagt gttacttgat gataaagata tatataaaca cactgaaaaa gaactatctg
    10441 cacttagaag aaaatccttt ggattcgtct ttcaacaatt taatctttta cctgttctta
    10501 cagcatctga aaatatttca atgcctgtac ttctagataa aaaacaacct gataaaggct
    10561 atttaaatga aatttcatca ttacttggaa ttgcagatag actcaatcat cttccccatg
    10621 aactttcagg cggtcagcaa caaagagttg caattgctag agcacttatt gcaaaaccag
    10681 atataatatt tgctgatgag cctacaggaa acttggacag taaaagtggc agtgaagtta
    10741 tgaatcttct tataaaaact tcaaaacagt ttggaaagac tttagtggta attactcatg
    10801 atgatagaat tgcaaaactt gctgatagaa aaatttcaat tattgatggt gttcttatgg
    10861 aggtgaaata gaaatgaaga attacctttc actttcaata aaagaattaa aaagccagaa
    10921 acttatgact acattcataa ttatagcaat agtactatca actattatga caactgtggt
    10981 tggacagtca attggtatcc tacaaaattt aagaattgaa caagcccgtt cttttaatgg
    11041 tgatagacat gtatcctttc accaactcac taaaaatcaa gttgatgaca taaagaaaga
    11101 tgatagagtt tatcaagctg gtacttcaat aactattggc agtagtaaaa taaaggattc
    11161 tggtatctct gtacttgtaa aagagtatga taaaacagga ctttctaact acccaaaatt
    11221 aatgaaatta aaatctggac atttgcctaa agataaaaac gaaatagcct tagatgaaaa
    11281 cacactaaag cttatgggta taaaaccaag actaggagtg actataccta tgaatttaga
    11341 tatttcactt ttaaatgata ccataccacc atataattac acagctaact ttaaattgag
    11401 tggcatttta gaggatgatt atacaggata tgtaagtggt atagtaaatg gtattgtagg
    11461 taaaggtaca tcagaaaatc tattacctaa gagatatact ttatcctctt tggattttaa
    11521 aataaaacag caagaaaagt ttcaagaaat agtaaatcaa ttagctaaaa aaataaatct
    11581 ttctcacaat tcaattcaat ataattggat ttacttaaat gctcttaaga tacagtttga
    11641 aaaagatgaa aatagttcta atagtgatgg tatatctatg attatattgg tatctttatt
    11701 tgttgcctta ttggttttac tggcttctgg acttgtaatc tataatattt taaaaatctc
    11761 tgttacaaag aaaattaaag agtatggatg tttaagagca ataggagctg aaccaaacca
    11821 gatatataag atagttattt tacaaatctt aattttatgt actgttgcca tacctattgg
    11881 agctgtaatt ggaattatat cttcgaaagg cataactgga atggtcacta atatcttaaa
    11941 tccagatata cttctagcaa atgataataa agaaattact gagcttatac ataaaaatac
    12001 aacagcatat atgttcccat tagtattaag cactaatgta tctttgattt tttcatttat
    12061 ttcagcatta ccatcagcaa tatatgcttc acatgtctct cccaaaattg ctatggttgg
    12121 tagtactacc aaaatcaaaa gaaaaattaa aagagaaaaa acaataaaaa actttgaaag
    12181 acatctagca tggctaaact taaaaagaaa taaaggaaga actataataa ctatactatc
    12241 attatttatg agtataacag tattcgttgc actgagtgag ttctctaatg tattagatgt
    12301 atctaggtca gtaagtaatt taaaagaagg agatttttcc ttaacaaatg aaatatctgg
    12361 ttttgataaa tcaacactag ataaaatagc taaaatgaaa aacgtcaatc gcacttcctt
    12421 tataaagtac tctgaataca aacagggtga aatagataca gatataaatt ttgaaaatag
    12481 tggtgagatg ttaaaaatca ttggaattga tgagcaaact ttaaaagact taatgccttc
    12541 tattacagat tctatactag aagactttaa aaatggttct atctgtttta taaaaaatcc
    12601 gattgctatt tctacaccag gtgtaaaaac tagacataca aatttaaaac ctaaagatag
    12661 tatcacaatc aacaaaaaac aactagatat atatagtaca gtagataaaa tgttcttttt
    12721 acaaggtaat ggctggataa atggtgttga tgttattgta tatgattctg tttataacac
    12781 cttgacaaat aaaaacaagt tcaaccagat aaatatttat gctaaagata aatcaaaatt
    12841 agaacaaata agattgtcta ttgaacagat ttgtgaaaat aatcctggct ctcattggat
    12901 atcatatatt gaatcagata aacaacttaa agagagtttt aaacaaatag aatttctagc
    12961 atgggcagtt atattatttg tgggattgat tggtacttta aacatcatta acacaactca
    13021 tacaaatata aatactagga ctaatgagat tggagttaaa agagctattg gtatgagtaa
    13081 tagtagctta tataaaatgt ttttatggga aggtgtttat tatggaattt ttgctgctat
    13141 atttggttca attgctgggt atgccagtgc tattattata aacatggcaa ctatagaaaa
    13201 gcttgatttc actaatatac caattacttc aattttacaa gctactatta tttctgtact
    13261 tgcatgtatt atagctactc ttattccgtt aagaaaagtt aaaaagatga atataattga
    13321 ctgtatagat atcaatttat aactatttta cagataataa tataaattaa attatcaatg
    13381 actgtctcta ttttctttca aatctaacta ataaatcttt ttaactataa tataagcttt
    13441 aaaaaaggcc tgtctcaaaa tagagataag ccttttttca ttgtcgaaat aatgaaaata
    13501 tatttaactt cacaaaaaaa gagtgcctca cgaattaaaa atttcgcttt gagacactcc
    13561 cctttaattt aaaatatata gttaaatgct atgccaaaat ttcacacatg ctccacctga
    13621 ttttgaattt tctattttaa cagaacctcc aagctgttcc actaattgtt tgacaatgta
    13681 aagcccaaga ccagaatgtc caccttttgt ctgcctagct tcatctcctc gataaaattt
    13741 atcaagagcc ttttttaaat ctttagagct aaaccctcta ccagaatcac aaatctcata
    13801 agaaatacaa tttttttcat cctttacagt aatactaata ttaccacctg atggagtgta
    13861 ttgcagactg ttggatatga tattatcaaa aattcgtgtc aacctatcca cgtcgatttg
    13921 aattggggat tgtatattcc cctgcatttt caatataagt tcaacttcct tttgatgagc
    13981 ctgtaattca tagtcttgca ccttttgcct caaaaattca ggtaaattta taggaacaag
    14041 atttaattgt atatttgact tttctaagtc agacgtatat tgcatctttt ggacaagagc
    14101 agcacttttt tctgtatttt ctcttatcac tgtaagatac ctatgaagtt tttcattgtc
    14161 atctgtatta ttaccaataa gtgcatctgt atatcccaaa ataatagaaa gaggagattt
    14221 taaatcatgt gctagagctt ccaccatttc aacacgttcc tgctccatct tccactgtgc
    14281 agataaagag ccttttaatt cgtctttcat ttcagaaaat gcactacaaa gtttaccgag
    14341 ttcattatct gaataatagt cgatttcaaa atcaaggtcc ttttctttta tcttcttgga
    14401 cgcatcaatc aatagatgta atggttgatt gatattcttt acaaagcgct tagaaagcca
    14461 tctagtaaaa cccacgatat atagaaatgg agaaaacaga gccattataa taactgcaaa
    14521 tacaaatctc cctctaatat ttgcaaaggt gattttcact tggtagaata gaataacagc
    14581 tccctcaatc tttccattat cccctttgat tggaacagta tggatataac cacctttacg
    14641 aacagtttta ttgataaaat tattaaataa ttcttctttt gttttaaata gttttttggg
    14701 gttagtacca tataaaatat tgccattatt atccacaact tgatatagca tatcatcccc
    14761 acgaatcgtt ctttttaaac cttcttcatt cgattgtgat aacaaagtta tgtttttttc
    14821 attgatgtat ttttcaattc taggaacttg tcgctcataa tagtttggtg gatagatatc
    14881 cttatttaag gaatgaatat acaaatagag agcaaataca taagtaatca ctgtggcaac
    14941 tatactggct attataataa aaataaaagt atgtctaaat tgggtaataa gggattgatt
    15001 tttcatttaa taacctctct ctctttacat tttattccac ttatacccaa taccccaaac
    15061 tgtggaaata tattcttttt ctggtgtcac agcagaaaac ttagctcgta ttttttttac
    15121 tcgttcaaca acagttgagg aatcaccttc agaatcacac ccccatactt tttcatagat
    15181 ttgttctctt gagaaaactt gtcctgcatg gagtgctagt aattcaacaa tatcatactc
    15241 tatttttgtt aaatcaatat tcttaccatc aattttaatt gcacgttcct tcatatataa
    15301 gcataacttc ccaaaataca aagtagatct cttgttctct tcattgatat actgtgaacg
    15361 cttttcccta cgcagattag cttcaatcct tgccataagt tcacgcagtc caaatggctt
    15421 tgttacataa tcatcccctc caaaggtcaa ccctttgatt ttgtcggttt ctgattgctt
    15481 tgcacttaaa aatataattg ggcataaaac atcatctcta attgcctgac atacctcaaa
    15541 tccattcatt ttaggcatca taatatccag tataataagg tcaggctcct gttttgataa
    15601 ctctatacct gcctgaccat cataagctat caacacttca tgtccttttg ccttcaattc
    15661 atcctcaagt agcattacta ggtccatttc atcatcaata atcaatattt tactcaatat
    15721 aacaccacct ttctcttatg ggaaggtcag tattaaaaca atattcgtct actaataact
    15781 tttccttccc tcccacattt taaaccaaat aacgcctcct atcaagaata taatcaaacc
    15841 tattgctact actataagct ctatactagc tgtttgcatc actttagagt aaaatgcctc
    15901 agttgaaata gttccagctt ctttaataaa ataaattcct ggaagcatac ctagttttac
    15961 tggccatgtc catggaacaa atgcccatac tttttcacca acgctagtta atccaagtat
    16021 tgctgccatc aaaattccac cgatactaat accaatagat gcacccatac cccatgcaaa
    16081 actcacccaa agatgaatag ctaatagtgg aagtgtccca atcaccacaa gtcctgctgc
    16141 tgacaggaat aaccatattg ttgctccaga tggcactgca atactcattc ctatgcaaag
    16201 tatcaacgta gcaataaatg tgcatatagt taggcaaaac agaagaaaaa gaaattttcc
    16261 cagatataat ctaacacgag aaatacctac acataaaaaa ccattaaaat ttccagcaag
    16321 ctcttcctcc tgcactataa atcctgctaa aatacctact ccaataggaa tgatgaatac
    16381 agtccatact gtaaaaaatc cttcaaaagc aaattcttgt gtacttccag atttagttgt
    16441 gagataaaaa accacacata atgaaaaaat aataggcata aaaagagtaa gccactggac
    16501 agctgtcctc tttgctcgaa gccattctga tgataatagc tttatcattt gtcatccctc
    16561 ctattgaacc aagctgcagt aagtgctgtt aatactataa acacaaccaa agaaacaaca
    16621 atcccaatag gaatcactga agtattcaaa agtgggtctc cagcttctaa tatagtaccg
    16681 ttaggatgta tgttgatgat tgggcatacc attctaactg cccaactcca aggtactgca
    16741 atccaaaatg gttttgtcgc agcaaggaca ccaaatatca tacctaaagc tccaactccc
    16801 atacttagga acataccttt ccatgtagct agccatagct gaagtggaag tatagcaaga
    16861 gaaacaaccc agcatacaat acttgcccct ataatctgtc caaaaggaac tggaccagct
    16921 ttcaatatta aaccagttat aattgttacg actattaaaa ctagcgttga aataaaactg
    16981 tagactgcca tagctataac tttattaatc caaagtgtca taggagacac attgtgtgta
    17041 cgtaaagcac gataatttcc agcttttttt tcctggaaag ctaccaaagt agcaaacaat
    17101 gcaaatccaa taggcagaaa taaaaatgac caccagttaa aaattaatgc taaaagactt
    17161 tgccacgccc aagaagttgt ttgagataat ggattttgca tgagtgttga ttgcattata
    17221 aatgcatatg ctgcaaaaga cactgggaaa aaaacaataa gtttacccat aaatgttctt
    17281 ttatacttta aaagttctga ttgtaaagca ttcatctgtt ttgtcctcct ttaagaataa
    17341 catctgtaaa aaattcttct agattttcat tagggtcagg cattccttga aataatagtc
    17401 gtcctccatt tataattcct atattatcta caacttgagc aacctctgat agaatatggc
    17461 tagaaagaat tacagttata cctttttttg gaaaagaagc aatcaattca cgcaattctt
    17521 gaatgccaaa ggggtcaaga ccattggttg gttcatctag tattaacaac tctgggtcac
    17581 tcaaaagtgc aatagctatt cctaaccttt gtttcatacc catagaaaat tgtgaagctc
    17641 tctttttacc tgtatttttc aaatttacta tttccaacac ttcataaatt ttatctttag
    17701 gtattcccaa tatttttgta tgtactaaca aattttcctc tgctgtaagg tttccataca
    17761 atgcagggga ttctattaaa gaacctattt ttgcaagaga ttctcgtttc caaggctttc
    17821 tatcaaaaat aatacgacca tttgttgggc gaagaagacc aacaagcatt ttaagtgttg
    17881 tggactttcc tgctccattt ggtcctaaaa gtccatatat actatttcgt tcaatttgta
    17941 gagaaacatt gttaactgcc atttgttctc catatctttt tgataagttt tttgtttcaa
    18001 gaattaaatc tttcatatta atttctccct tcttgtaata ccttaaatct gttactaaga
    18061 gaatactaac atgaaaaaat aacaattcta taacacctac taattttaat aaaatttaaa
    18121 ataaaaaata gagttaccaa ttttattttg gcaactctat ttaagtttat gttttacagt
    18181 tatattagat ttaagcttag tttcattatc acactaactt caaatttact ctataatcct
    18241 taaatcaaac actaatttat taatcaaaca ctaatctatt aatttatatt tctttagaca
    18301 tctaatatag tttgctacta aataataatt atttatatca tatttatcta atcctttaaa
    18361 agaagttatt tcatcattaa gctcatcact accttctaca aaaacataac ctgtttcaaa
    18421 ttccatacct acaataatct tacagccact ataaatttcc tcttgagtat cgtacaattt
    18481 ttttgcattt ccttcatttg gaattgtaaa tacaataggt tttaattctt tatcactgga
    18541 aatcttttgt gaaaaaggct tgtttaactt aatattattg ataactacat gtttaaattc
    18601 ctctgaagtt tcttctacta ttacatattt tcgctttaaa aactctatta tttctaaaac
    18661 agacttagaa tttactttta aaatactttt atatttttca tataaagatt tccactgttc
    18721 aattttttcc tgtggtactt cttggatatg tgtacttatt ttttcttgag atattttttt
    18781 caattaaact ctcctttcaa tacttaaata tccttataaa tctcacatga ctaaagttac
    18841 aaggttccta cttaatagaa ttttgcatac ttaaatatgt cttattaatt ctctacagga
    18901 tatctccgta gttcctacga ttcttacata agttacttat tttaaattgt tattagttag
    18961 attataaaaa ttatttattt tatcactaat ataatactct taaaaacttt acaaatcaat
    19021 ttaaatttgc taccttttat ttataacaac ttatagtaca tttctcctat gcttttcaat
    19081 atattacttt taaaaggagg ttttcattat gattttaaat agagctgagc ttttccgagg
    19141 atattcttta aatagattta acgagatatg caatatatta tcagtaaata aaattaaata
    19201 taagtataaa gtgaaaaata atgcttactc taaaaaacct ttttttaatg aaataacact
    19261 tggcaattta ggccaaaagg aagatttctc ttatgagtac ttaatttatg ttcataaaga
    19321 cgattatgaa caggcagagt ctctaataaa ttctaagttg cgatagatta tctataaaac
    19381 atgacattct gttgtcatgt tttatatgtt attatacttt caaatatgct actatatttt
    19441 caaaattgtg tgctttaaaa ctagcttttt ttagtaattt aaagcttaaa actaaggaga
    19501 ctcgttatat gaaaataaat ataaaatcaa agttaagtga atttattaaa cagaacaatc
    19561 tttttgatga cagcagaata atatcctatc ttcctaatat aacaatagaa acagacaaaa
    19621 taaaaactat aatgattaat gaggttgtcc caactaacac caatgacgat ttttatagtg
    19681 tagataaaga tgctgattat ttaaaaacta ctattccttt atttgacagt gcaggaataa
    19741 aagtatctaa cataaatgat atcctagata tgggtatcta tataactaat gcagtaaaac
    19801 ttcctaaatc agaatataca ataactcgtg atacaattaa attacatatg cctattttag
    19861 aagaagaaat taaattattt aaaaacctag aggtagtaat gttaatggga gatgttgcaa
    19921 aaaaatcttt taatatgatt actaaaaagc atataaaaaa gaatgtcatc ccttccattt
    19981 caacatataa acttcgtaat aatgaacttt attatgataa tttaagagta tttccatcat
    20041 atattatgac tggtggaaac atactgattg aaaaatcaaa atttgaaatg gcatcagaag
    20101 atataaaaaa aatgttcgag attataaacg gttgatatta caaaataata aaaactaata
    20161 taaaataaaa agtgcctcaa aaacttctat ttatgaggca cttttatttt atattagtgt
    20221 aactatatac tattaacata atttattatt tatattgttc cttttaatct ctattccatt
    20281 tagtctaggt aacattactc tttacaagat tactttatat ttcttttata tctctaacgt
    20341 ttttatttaa taaaacaatt attaatacaa gtcaaatata tctatttatc taaaaatata
    20401 tcttttacag taatatctgg atggtgatac ttcttcctat tcgttaaaaa agattttttt
    20461 acattaatag cctcttttgg acaccagtga aaacaagcta ggcatctttc acactcatta
    20521 ccccactttg gctttttatc aactatactt atattctcta caggacaaac ccttttacat
    20581 gtcccacatc tattacattt attttctgca aaaaatttag tagttgcaat ttgcatattc
    20641 ttacctacta aacgaagtac aacactatct atatgtgact ttaaattgtt ttttccttct
    20701 atatttccaa tctccaagtt attgatacat tttgcaatct cagctaccct attagtctga
    20761 tttttcaatc tttcttcttc aacatctgga ggtgttatca aagcatttcc aggcatattg
    20821 attaaaaaac cagcagataa ttttttcccc ctttttttaa gtaacttatc tatagtaaat
    20881 aaactatgtc cagctacccc attacaagtg gcaatggcat atatatgagt attaatatta
    20941 aaatttaatt tctctacaaa agactttact atatcaggaa catcagcaaa ataaacagga
    21001 aaaacaatta ccaatatatc ttcatttatg tctatattat tttcttttct atgtatagct
    21061 aagggtataa cttctttact tccatttaac gtttctttta aaatatttga aactactagc
    21121 gaatttcctg ttccagaaaa ataataaatc ttactattca ttcttatccc tctttctata
    21181 tttctacatc atcaatagtt aaaaagtctc ttaaaatagg atttatattt actttccaat
    21241 tctatccaaa atatcagtaa acaaaggcaa ttcttcatca gagatagatt taaatgtctc
    21301 tgttgcatat atacttgcaa tttcatttaa tggttcttct aattctctac ctaaatctgt
    21361 taggaatatt tgaaacttac gtctatcttt aacatctact ttacggacaa ttaatccctt
    21421 atttttcata acatctaaga ttcttgtcgt attagattta tccttacatg atttttcaca
    21481 taaatctatc tgagaaattc catcttgctc ccatagaaac cttaataacg cataatggtc
    21541 agttgttata tcatatccat tttgtttaaa catctttttt aaatcatctt ttacttttaa
    21601 cgaagtactt actaacttag ttgtagcttc atatagtttc tcaaaatctt tcattttacc
    21661 tccatttaaa taatcccttg ctcctcccat ctatcaatta ttcccttata ttgctcaata
    21721 tctttaaaag ccattggctt taaaacagca tttatagcaa taaaattata gatttgagaa
    21781 agcacaggtg gatttttctt ttcctctatg caataaataa attttttaga taccttttgt
    21841 atctttgatt ctactttttc agttatagga ttttgattaa atccagtttt tatagataaa
    21901 ctaccacaaa cataacctcc cgaatctaag accatggatt ttataaaaga aattgctttt
    21961 gaaccacgtg cattttcata tgtagtaact gctatacatg gcttacgata caataatctt
    22021 tcaagcatca tatgtgctct atctgtaaac accttgaaaa gtccagttac actacttcca
    22081 taagttgggc taccaaatat aacaccatca ctcttagtaa ttatatcatg aatatactct
    22141 actttatcat tttgattgat acacttgccc attttataac aatttaaaca accaatacaa
    22201 tatgatggat tgacctcact taaatcaaaa taattaattt ttacatctgg tattaatctt
    22261 tctatatctt tatacaagta agtcaaaact tttgatgtag ctccattttt tctagggctt
    22321 ccatttataa ctgtaattat catttctata tctccttttt agttgttata tcaacaataa
    22381 gtatatcaac tatattttta gctgtcaata taaaccattt atttaaagct atacttacac
    22441 agcttaaata aaagttttat ttaactacat gtgcttattt aatcaactat aaatgaatta
    22501 tttttaataa ttgacaaact aaattaatga taatatactt tatgtattac aaatgtaagt
    22561 agaaggaggt atagtatgaa aaagttacca catatttcag aagcagaata tcaagttatg
    22621 aaaattattt ggaaatatgc tcctatcagc actactgaag taattgaaaa gttggtagaa
    22681 acaagtacat ggagtcctaa aacaattcaa acaatgttat tgagattagt taaaaaagga
    22741 gctttaacat atgaaaaaaa tagcagagta ttcgtttata ctccacttgt taaagaagaa
    22801 gaatacgtag ctacagaaag tagttctttt ttaaatcgtt tttataatgg tactcttaat
    22861 tctatggtac taaacttttt agaaaatgat aaactatctg aagatgatat tgaggaactg
    22921 agagaaatct taaataaaag gacgactaag ggggataaat aaatatgtat gccccattct
    22981 ttatacgatt tttactcagt acattaacct tatcaatatt aattgttgta attttacttg
    23041 ccaaaaaagt atttaaaaaa catatttctg caaagtacca atacaatatt ggatttatat
    23101 tgcttataat gttaataatt ccatttgtcc ctcttaaata tattaatctt ggaaatgtat
    23161 ttaactattt atatactttt aatcaacttg gaagcagtac taataggact tctatgataa
    23221 aaaatagttc aaattctgta attaataact caaatgcatt aaacgatttt tcagtatccc
    23281 taaatcaagt taattttgat agtttaaata ttttattact aatatcatgg ataattggaa
    23341 ttttaatcat gatagctatt actattcatt gcaacattaa aataaaaaat atgaaaaaat
    23401 caatacaaat tttaaaagat gaggagatag tatttatatt tgaaaagtgt aaaaaagata
    23461 ttggtataaa taaggatttt atactatgca aatcacctat tataaataca cctattacat
    23521 ttggatactt taaaccacac attatattac cagataagtc tatatctaaa ttatctttaa
    23581 aagatataaa atatatctta cttcatgaat tacaacattt taaaaataaa gatatactga
    23641 taaattatat aatgtgcttt cttcaaatat tatattggtt taatcctctt gtatggtatg
    23701 catttaaaga aatgcgtata gaccgtgaaa ttgcatgtga tatttcagtt ttaaaaaagc
    23761 ttaataaaga tagtcatata gaatatggac aaactctaat aaactttgtg gataatattt
    23821 caagaccatc aaatcttaca cttacatcag atattggtgg ttcaaaaaaa caaataaaaa
    23881 agcgactatt gaagataatg gattttcata atgaatcaaa tacgttaaaa ttcaaaagca
    23941 ttttaatttt tacattgata gctttaattg tatttggaaa tattcccaaa ctatctatta
    24001 tggcagatat caacgaaaaa tatagaccta caaatgaaca aactgtgtac gaggacttaa
    24061 gtcagtattt taaaggtttt gatggaagtt ttgttatgta tgatttaaaa tccaagcaat
    24121 atcatattta caataaagaa aaaagtaaaa caagaatttc tccaaattct acttataaga
    24181 tttatagtgc cttattggga ttggaaaatg ggataataac aagaaataat tcacatatcc
    24241 cttgggatgg aaagcatcat tctaatagtt cttggaatga agaccaagac ttattttctg
    24301 ctatggaaaa ctccgtaaac tggtactttc agactctaga taaaaaaaca gggctaaaaa
    24361 acatacaaac ttatcttagg caaattggat atggcaatta tgatgtttca ggtggtatct
    24421 caaacttttg gctagaatct tcattaaaaa tatcacctat tgaacaggta gaattacttg
    24481 aaagttttta tacaaataag tttaaatttg aagataaaaa tatagaaaca gtaaaagatt
    24541 cattgttaat atcaaaaaag gatggggtat cactttttgg taaaacaggc actgccaata
    24601 taaatggaaa agatgtaaat ggttggttta taggttatgt ggaaaaaaat gaaaatactt
    24661 atttctttgc tacaaatatt caaagcaaag attattctaa tggtagttca gcatctaaga
    24721 taacattatc catattaaat gacaaaaaaa tctataatcc ttaatatatt tactgtacat
    24781 tctaaaaaat tcacataatt ttcatattaa ttatcaatta aattcatata caaggcttat
    24841 tatataaaca tagaagatag taaaactagc ttaaaaacat aatataatac cctatacaaa
    24901 tagtggcaac tctccctcac atcctcaatt gttgccacta tttaattttt tgtatgaagt
    24961 taaatatatt ttcatcattt caacaatttg ggtgcaatac aatctctatt ttgaaacaac
    25021 ctctttaatt gttttagagt ttatgaatta tttctcatac tttaaaaaga ttgaattact
    25081 cttgataatc ttcttttgta gtcattacat atcacctact actcaacaca tattctttga
    25141 cctattttta catccttgtt tatatccaaa atatttacct tcttaccatc tggaaacaat
    25201 accattgtca aagtagactt tcctaattca tgtattctct ttaaatcaac attaacaaga
    25261 acgtctccct gtttaaccat atctccttgt ttaacagcaa catcaaagcc atctccattt
    25321 aatgcaactg tatcaattcc aacatgaatt aatacttctc cattagttcc tttaatccca
    25381 aatgcatgtc cacttgaaac cactgtttct aatttacctg aaataggaga aacaattttt
    25441 ccatctataa tatcaatagc aaaaccatca cctaacattt ttttagaaaa tgtttcatct
    25501 ggtacatttt ctaatgcaac aattttcccc ttagctggag acacaaagtt ttcattattt
    25561 tcattaaaca ctaattcttc gtcttcatct tcatttatag cttctttagg cactccaaat
    25621 aaacatgtta caataaagca gaatgcaacc acaaatattg atactaataa gtatgtgatt
    25681 aaattatatc catcatagat atacattaaa taagaaggta aaactgctaa tccatatgaa
    25741 ttagattgaa tatgtaaaat tgataatatt gctgctccta aacctgaaga tgcacacata
    25801 ataatcaaag gctttaaatt atatcgaagc tgaatcccaa ataaaacagg ctcacttata
    25861 ccaaaaagtt gagatagcat tgctccaacc gcagtttgtt taacttgatt atttttagat
    25921 tttttcataa atgctagaca tgttccaata ttcgcaaatc catacattgc acaaagagta
    25981 ataagggcat taaatcctgt atttgctaat agtgatgttt caatcattac ataagtatga
    26041 tgtaagccag taataacagc taatggatat gtaaatccaa taataaatcc tccaattcct
    26101 aaaggcaaat caatcaataa gctgatgata tcaaccattt ttaattctat tgtatgcatt
    26161 atagggccta cacctaacaa aataactaac attgttatta gcataacaaa aaatggtgtg
    26221 aaaataaggt ctaatacatt aggcatatgt ttacggaacc atttttcaag attagctcca
    26281 ataaatgctg taacaatagc tgttaaaaca cttccttgac aacctacaat aggaataaat
    26341 ccaaatgcca taattgcttc aatttcattt gatgggtcag caacagaata tgcattagga
    26401 agtattgggg aaactaacat aagtccaata acaagtccaa taacaggtgt tcctccaaat
    26461 actttaaatg ctgaccatac aataattgct ggtaaaaaag caaatgctgt ttctgtaaga
    26521 accgaaacaa gtgtctgaat atacaatgga atatttgcag aagacattcc aaataatcca
    26581 agtacattat cattaaacaa acaacccttt aatcccaaga ataatcctgt tgctgcaata
    26641 actggaataa taggaacaaa tatatctgct agagttctca taactttctt aaatccagtt
    26701 tcattatttt taactaattc atcttgttct ttttttgata aagtttttaa tcccattttt
    26761 tcaacttctg cataaacttt attaactatt cctgttccta aaataatttg atactgtcca
    26821 gaagtaaaga aaaccccttt aacctcatca actttttcaa ctttcttatc attaataatt
    26881 tctctatctt taaccatcac tcttaatctt gtggcacaat gtgtaataga aataatatta
    26941 tcttcaccaa taattttaat aagctcattt gctattttat tatatttatt catttttcta
    27001 cctcactttc aataatactg catgaaatgg tttcaaacgc actgttttat ttaatagatt
    27061 tatatcatct aaattttgga atacaatatc atatttttct tctactctta tttctacagg
    27121 tttatcagaa aaattataat aacaatcaat aactaccaaa tctaattgcc ttctatacgc
    27181 aataatatca tcactttcta tatcaatagg ttctattgaa ccataaatca aacaatcaga
    27241 atactcacta tcttgtctca actttatcat ctttttataa aattctaaaa tactctctga
    27301 attgttaatc tgactctgtg cattaatatc tttataattt tcaataacct ttaaccatgg
    27361 tgttgtatct gaaaaacctg cattttcttt atctgcccat ggaaatggcg ttcttgcatt
    27421 atctcggctt cttaaattca caaattctaa cgcttcttct tctgagtaac tttcatctat
    27481 tgaacgatag tattggtcaa tgctagataa atcattaaaa tcatttatgg tatctctttt
    27541 aaaatttgtc attcctaatt cctgtccctg ataaataaat ggggttcctc ttaaaaagaa
    27601 atacattgct cccaacattt ttactgcatc atcattcctt tcgtattgca aaagatactt
    27661 tgttgtagct cttggttggt catgattttc aataaaatta gctgcccatc catgttcctg
    27721 aacatacatt tgactatcta aaatgcattt tcttaaatct ggaattgtcc atgaaattct
    27781 tttaaaccac tcactaccag aagcaacatc taagtcagca tgtttaaagt caaagaccat
    27841 tgaaaagaaa ccatcttctc caataaaatc acctagctgg tcatagctaa tacctgctgc
    27901 ttcagcaaca gtcatacaat catatttttt aaacgtattt tcttttaatt cataaagcat
    27961 tttttctatt ccaggctgat ttctaactgt ttttgtacat ttaacaagac catcaacacc
    28021 atcactttct aaactttgaa aacttaaatt ctttttgatg aatgtaatag catcaactct
    28081 aaatcctgcc actcccattt gagaccaggt attaatcatt tggtaaagtt cacttcttaa
    28141 tattggattt tcccaattaa ggtcaggttg ttttttacca aaagaatgaa aataatattc
    28201 gtctctattc tctacctttt cccaaacact tccaccaaaa acagacctcc agttatttgg
    28261 taaatcgttt ccttttttaa aaatataata atcatgataa ggactttctg gattttttaa
    28321 tgcttcttga aaccaaggat gttcatcact tgtatgatta agaactaaat ctaatataat
    28381 tttgattcct ctatctttac tttctttaat taactctttt aaatcttcca tacttccaaa
    28441 ttcacttgca atatccaaat aatcactaat atcataccca ttatcgtcca taggtgattt
    28501 aaaaattgga cataaccaca atgatgtaat acctaaattt tttaaataat ctaaacgaga
    28561 aataattccc tgtaaatctc caattccatc attattacta tcttgaaagc ttcttggata
    28621 aatttgataa acgatttctt tttgccacca tttcttttcc ataaattact cctttttata
    28681 tgatatttct tctttttaat tctttataaa ttccattatc gaatatgtcc tcacatatag
    28741 atgtcgctat atctttaagt tgttgatgac tatttttcat tgcaattgta acgtctgatg
    28801 cttgaaacat gacaacatcg ttttgaccat caccaaaaca tatggtttct ttttgagtta
    28861 ctcctaatct ttcttgtaat ctcttaattg ctttgccctt atgaaaatct ttttgaataa
    28921 tttcataata ctgactagaa atatctctct gtgctaattc cattttatct tgtagtatat
    28981 ttttcacttc gtcaaatacc ttttcatttg accataaaca aattttatgt atatcttgtg
    29041 acttatactc ttcaatgtta ttttcatatg ttattttttc ttggatatgt tgtttattta
    29101 tacaagaatt agttcctttc aactgattca ttgtttcaaa tatttctttg gctttttgat
    29161 tcatgaaaac tttttcctga ctctcaatcg aaaaagcaac ttctctcttt tttaataaac
    29221 aaacaacttc ctttatcaat ctttgattaa aagattgatt ataaagtaat tcaccatgat
    29281 attgaatgta attacctcct cctgcaatat atccatcaac tcctaatgat aaaacatcat
    29341 cttgtattgt acccatactt cttccagtac aaataacaac actgcaatga ttcttttgac
    29401 ataaacgtat agcatgcttt gcagattctg ggattccata tacctcatct ctaagcgtac
    29461 catctatatc aagtattaat aatttgtaca atttcatctt cctttcttac tatcaaaatc
    29521 ataatagcat tcaaaaaaaa agatatcaat attttgatat cttttaaaaa atatgttcat
    29581 ttttagcaca aattttcatt ttcggggaat atgttcactt tctaaataca tcttgtattt
    29641 aatataaagc agttcaatta aaataaaata aggtgttgtt acatcgtagt ccagttgttt
    29701 atctacagaa atagatatag attgaatata caggttttca tcacataatc ttgctaaagg
    29761 attacttatc atttttgtaa tagaaaccat ataaattcct ttcattctca tttctttagc
    29821 aaaatcaata attgtagatg catctccatt caatgaaata aagaaaatca tatcatctgt
    29881 ttttataaaa tgattaagtg cctgaatcat atcataacca taaacatcat atataatttt
    29941 ccctgttggt aagaaaatcc ttttcatctc tttagcaact ctttcctgag aataaccttc
    30001 tccaaagacg attatacgat ttgccttttt cattctttca aacataatcg aacaatcctt
    30061 cttctctata tcatctatca ccttattata acaatccatt aattggtgtt tactttgatt
    30121 tttatattct acttctgttt catttaagcg tataataact cttaattcac tatatccagg
    30181 taattgtagt ttttgagcaa aacgagaaag tgcacttgta gatatatggt atttgtctgc
    30241 aaattcatct atagaaagtt taatacaatc ttctttatga ttaagaatac actcacagat
    30301 atacttatca tttgctgtaa atgaattata atatttattg aaaagtcctt caattttcat
    30361 tcttttctcc ttctatactc tatgtaattc atatgaagca aatctaatag agcataaaat
    30421 gctcctacga cttcataaga tatagcttgt aatgtatcaa gtttttgcgt ttcaacatac
    30481 agattatact cacaaagtgt tgcaattgta ttattatcaa gcctagttaa agaaatcgta
    30541 tgtatatgat tgttgataaa ttttgcaatt tcaattcctg cttttgtttc tccagacaaa
    30601 gaaatgataa taaataaatc atttttttga aatgattctc tcataaattc aatttcacct
    30661 atatcaaata agtcaataac acatttacct actgaaagaa atattctctt tatttcttga
    30721 gctaaacttt tctgttcatt acctgtccca taaatataaa ttgtttctgc atcatatatt
    30781 attttacaaa tatcttgaaa tgatattttt tgtaattcat tcattaatag tcgataattc
    30841 tcgcaaacat catgaaaatt attatcatta ttaacaaatt ctagttgatt atttttaagt
    30901 aaatacttta aatcagagaa tgaatctaat ccaatttttc tacaaagcct taataaagta
    30961 gctctagaaa cattacattc atttgcaatt ttttcacacg aaaaattacg gtattctctt
    31021 tgacaaatca atatttgttt aataataatt ttatcatttt catttaaatt atcataattt
    31081 tggttaacta acgattctaa tctcattttt tccactccct aaatattatt ttaatataca
    31141 ttagttgctt tttctaggga agagttttaa ataataagga taaaataatc atttgatttt
    31201 atttttatta aaataaaaat aacctgctaa aagcaggcac caaaaagtac ttatcctttc
    31261 gaacatgtac tttagatatt gctttcttcg gaagcttcat ctcttcatac tctaaaatat
    31321 agttttttct aactcaaaag tattttccat ggtagaaatt actttaattc atctgccatt
    31381 tactttttat cttatttaat aattactatt acttgaatat ttacttcttt aagtaaattt
    31441 catagttaac aaagctaaaa ctattattat agatgttaaa atacaaaatt gtaagtattg
    31501 ttataaatat gcttacagct acaaatatac atgatatatt aaaaagaagc tgtaaattat
    31561 tatcatacat acaagcaact atgcctctat taatccatgt taatttttat tatttaatac
    31621 aaggagttcc atgagacata catatccatt catattttaa attatccaat tctcttatag
    31681 atttcaccat ctttttataa tcccaattcc atggattagg ataaggaact atatttccat
    31741 tcttattttt gactaaatca cctgcaaata atacagcttc aaaaatcatg cagacatgcc
    31801 ctggagtatg accaggagta tggataattt ttatattccc aatctgcata ttctctccat
    31861 aaggttcaac atccttaatg agccttctgg aaattgcctt tccaataaac ttcttaaacc
    31921 caggtctatc cttctctcct ataataaaag gtatatcctc tacatgagcc catacttttg
    31981 ctcctgtttt ttctttcaat aatttaatat tagatatatg gtcaacatca tgatgagtta
    32041 ataaaatatg cttaatatct gtaagtttaa tgccaagtgt ttttaattct ttaattatat
    32101 ttttccccat aaaaggaaga cctgtgtcta taagaataat ttctttatca aacacaataa
    32161 aacaatttga gccacgagta ctatctaaca ttaatacatt ttcttttatc ttcataaata
    32221 aattcccctt atttggtatt ttacctatat aattaattaa taaagttata aatagttata
    32281 atacttgata ttaattttat tttttattaa agtatactat aggtatacaa gtattatatt
    32341 tacataagta taccatcagt atactttttt atcaatagaa aggaataatt tatatgtcag
    32401 aattatcaaa aagagataaa gaaaaaatac aaagagaaaa tgagattatt gataaagcag
    32461 aaaaattatt ttgtcttaat ggatttgata atacaactat gaatgaatta gcaaaagaag
    32521 ttgaatatac taaacgcacc atatacaagt acttttcatg taaagaagat ttattctttg
    32581 ctgttgtctt aagaggatat aaaagacttt gggataatgt taaaatagaa agtgcaaaag
    32641 gcaaaacagg gtttgaaaaa ataaaacttt catactttgc ttttcataaa ttttactctg
    32701 tagaaccttc tctattatgc cttatgggaa tgattggtat tgtaaactct gaaaaatcgg
    32761 atactgatat gctgtttaaa gaaaagtttt tttcttttaa taaatttatg tttgatgaaa
    32821 tacaaggaat gtttgaaatt ggaaaaaatg atagaagtat taggcatgat attgaaatac
    32881 ctactcttat gtattcatca atatttacac ttacaggatt ttttaattta ctatctgtaa
    32941 caggaaaatc atacctgaac aactttaata tagatgagga aaaatttatt gaaacaactc
    33001 ttgctctttt aatagattca attaaagcat aaacctaagt ttataaatta aagtttatat
    33061 acttaaatga taattttttc tatctctaat ataaaaaata ttaaacataa aactaataac
    33121 ttagttaatg gaataactaa attactgaaa ggattaaaag taaatggcta aaatacttct
    33181 tttagaagat gatgatacaa ttacatttgg aataaaaact tcccttgaaa agaaaaatca
    33241 cactgtatgt tgttataata cgattgctga agctaaaaaa aattttgata aaactattga
    33301 tttaattctg cttgatttaa atctacctga tggtattgga tacgagtttt gccaatatgt
    33361 taaaagtata gaagatactc cagtgatatt tttgacagtc cgtgatgatg aaaaagacat
    33421 tatacgtgga ttagatatgg gtgcagatga ctatgtggtt aaaccgtttt tgctctcagt
    33481 acttcagtcc agaattaatg cagttcttag aagaactcat tcaaatacta acaatactat
    33541 tacatgtgaa aatataagct tgaataaggt tgaagtcaaa gcatatttag ataatgttga
    33601 agtacctttg acagcaggag aatataaact tcttctaagt cttatggaaa ataaaaatag
    33661 agctatgact cgtacaaagt tactagaaat gctctgggat gtagatggta atttcgtaaa
    33721 tgataacact cttactgtta caataaaacg tcttagagaa aaattaaaaa atccaccttg
    33781 tataaaaacg ttaagaggca taggatatag aatggaggac agctagtgaa aactccaaga
    33841 aatatcaaca gtacagttgt ttttataata ttctgcttaa ttgtaacttt tttattgagt
    33901 gtaattctaa caactataac ttcttttaat gaatacaatg tactgtctaa ggctcttggt
    33961 gcatcatatg agtacaatcc taagtctaca gaaagtatac taaaatcact gaaaaattct
    34021 agtgataagg attttaaaac aggaaatgaa attttatcaa aacatggata ttctaaaagt
    34081 acattttgga gtaaaaactt tttttatttt ctagtgatat cgtttggtat aatttcaaca
    34141 atggctacag ttatatatat aatcaaacat agaacaaata agcaaaaact gagtagaata
    34201 aacaatctta ctcaatactt agaagaagtg aatttaggaa aagagtctgt acttttacga
    34261 tgtgaagatg aattttctca ccttgaagat gagatatata aaacagttgg ggaacttcgt
    34321 tgttcaaaag aatttgcttt aaaagaaaga caaactcttt cagataatct tgcagatatt
    34381 gctcatcaac ttaagactcc aattacttct atgtcactta tggcacaatt actttcagaa
    34441 aattgtccag atgaagaaat agattatatt aacagactta caaatcaaat ctcaagactt
    34501 gagagactag tttcatcttt acttacatta tcaaaattgg atgcaagtac tttaatattt
    34561 gaaagcaaac ttatagatgt acattctctt cttacttatg caattgagcc tatagaaggt
    34621 tctttaagag aaaaacatca gacatttact atcgaggctt ctccttcggt agaatttgaa
    34681 atcgatatta attggacttt agaagctctt ttaaatattc ttaaaaattg tagtgagcat
    34741 atagaagatg gtggatatat agttgcttat tatagtcaaa atcctctata tgttgagatt
    34801 atcatagaag ataatggtaa ggggtttgct caggaagaac ttccatatat ttttaataga
    34861 ttttatcgtg gtaaaaatgc tagtaaggac agtattggta tagggcttgc tctatcaaag
    34921 tctattatag aacgtcaaaa tggtactcta catgcagaaa attgccataa tggtggtgca
    34981 agattcataa ttaaatttta cacataaaat gctggattat aggtaaaata cctataatcc
    35041 agctatatct atattctatg ttatctattg ttttagtaat atacttctat ttacatttaa
    35101 ggttttatta aacaaacaac ttaactatcc ctatacttgt aagtagtctt aaatcgaaac
    35161 ctttaaataa gttcaaatag attttgttta tattgtttca ttttttatag attctactat
    35221 attttcattc ttcaactgct tgtatcctgt catatatgat gctattacaa taaaaagtat
    35281 caatatagta aaacctatta ttgtagatat aggtgcaaat ggtaaatact ctataaaata
    35341 tatttcattt atacgtagaa aagcatacac tattcctatt tgcacaggaa tactaagtag
    35401 taatggtgta attcctaaga ataaaccttc caaaataagc atctttttta tgccttctgg
    35461 agataatcca acagaacgca acatagcaaa ctcttgtcgt ctacttctaa tatttcctga
    35521 cactgtagca agtacatttg ataatccaat catagccaat aaacctgtaa taaagcctac
    35581 tattaaattc atggtcttta ttccactagc cttttgtttt tcactttcta aaacatcctc
    35641 aatactataa tctcctgaac catagtcttt attataaatg gactctaatt tttctcttac
    35701 tctaggaatg tcctcacgat tatttacttt aaatactcct atcagcctat ttgaacgtaa
    35761 cctacttact tcatcataat ttttagatat ttcctgtacc atagacattg gaactatttg
    35821 cattaatgta tactttgaac tagtatctac tattttagga agtgtgcttg taatagctcc
    35881 cactttcatg ttgtaagtat aatccccttt atcttcgtca tatacttttt catttaattt
    35941 aatgttatct cctattgaaa gatttaaata atctatatat actttatttc tacgtgtact
    36001 acgattaata tcttcctcct tattatatac aattgaggtt ggattttttg tattataaaa
    36061 taactttggg tctacagaaa tttgcctaca atattctgta aaactcttat catcaagccc
    36121 aattatattt gaaattatac gaaacttgcc atcacgttct ataggagagt attttttaga
    36181 tgaaactata cttttaaatc ctccattttt cgcaagttct tttgatgcat ctttttcagt
    36241 cagccaagtg gaagcagaca ttttttgata atatagtgaa ctttttacac cttctgtatt
    36301 atctaatttt tcaatgaaag cagactctat aggttcacta ttttccaaat aaactgctat
    36361 atctctttgg tccttataat tatcacttcc ataaacagct tttgctcctt cttgatttgc
    36421 aattatatgc aaaaaacatg taagtaataa aaaagataat gttaaagata ttgttgcagt
    36481 acgataagat tttttacgag cacgtagtgc gtttgatgca agttctcctt ctattccaaa
    36541 tatctttcct aatgaatatt tatgcgactt tttgatttta acactatctc cttgtcgtat
    36601 tgcttctata ggagatatct ttgatacttt tcgtgctggt ataagtgcag aaatccagac
    36661 tgttactatt gtaagtaaaa ctgctggcag aaaagcagga ataccataag taaataccac
    36721 ttctggaaca tcagtatgat aattaactga attaacataa actataagcc tattacacaa
    36781 taaccatcct aaaaataaac ctattggtaa tggtataatt gtcagtaaaa agccttcaaa
    36841 cactacagac cttttaattt gttttggtga tgcaccaaca ctagataata tccctaactg
    36901 agtaagtcta gcatttgcag acagtgaaaa cgcgttgtaa atcaccatta caaacacggc
    36961 tactgtaaaa attgctattg taagatacat aataggagtt gaaaattttg atatactact
    37021 catagatgct ttctgttctg gtgaaaagac taacatcttt aaaagataat tactattgta
    37081 tttaagattg tattttccat attcattagt cttccatccc aatgatttag caagttttgg
    37141 aagttcctta tacgtgtctc ttatattttt aaatcgcaag tacacagtta tactatcatt
    37201 aggttttata cttgttttat caagatatcc aagagctgta tatgcaggta ttactgatga
    37261 agtagaaaca tctacctttc ctactattgt caatgtagcc tctgaaattt ttttaaaact
    37321 ttcccctttc gattttgggg ctatgggttc aagaggcttt ccatttaaga ttctatatcc
    37381 tattgggaga gtaattttat caccaatttt tacacttgga ttattctcaa aatattgttt
    37441 tgataatgca atttcattag cattatttgg tcgacgaccc tctattatag tatccttttc
    37501 tggcatagaa ttccaatact ctgatgtagc atttctataa attatataat ctcttttctc
    37561 atcattaatt ttgcctacat accattgtcc ttttaccatt acatcatcaa ctgaagaaaa
    37621 attttcaatt aatggtaagt cacttccata agtatagtca aacaattcac catgccagtt
    37681 accttctttc tcaattgaaa gtcttataaa atctgtccac atggtataca acagtccaca
    37741 caaagaagac atcatggttg tagtaagtaa tatagctaac attatagcta tactactacg
    37801 tttattgcgt cgtacaaagt ctaaggtgta ttcttgaaga atattcattt cttcaccacc
    37861 ttttcagaga caatcactcc atcttccata gttacaatac gatttgcctc tagtgctatt
    37921 ttctcatcat gagtaataag aagtattgtc tgattaaatc gtttatttga taagtttaac
    37981 aagtctacaa tttcttctga attttttcta tcaagattac cagttggctc atctgctaat
    38041 aaaatagctg gtctatagat taaacttcta gctatagata ccctttgttg ttgtccacct
    38101 gaaagttgac ttggaagatg gtttaatcta tcagataatc ccaatataga tacaatctca
    38161 gagaatctat cctcatccac ctttctttta tcaagtaaca tgggtaataa tatatttttt
    38221 ctaacatcaa gggtaggtat aagattataa aattgataaa taagacctac ttttctacgt
    38281 ctaaaaactg caagagcttc ttcctttaaa cttgatattt ctgtatcttc aacataaatc
    38341 tttccagatg taggtctatc tactccccca agcagatgta acaatgtaga tttgccagaa
    38401 ccagatgctc ctacaatgga tacaaaatca cctttttgaa ctgataaatt tacattatta
    38461 agggctgtca ctctggtttg atttgaacca tatatttttg tgagattttc acattttaat
    38521 atttccatat acaatcatct cctttatggt taaattttag caacctaaaa tgacattata
    38581 gtgacatgaa tacaaatata aattactatt aaaaatattg tttagttttt gcacattatt
    38641 taaaattata atataaaaca aaaactatgc aatatatttt atttatactt ttaatatatt
    38701 acatagtctt taaaaggtat taactttaaa tctataggta ttcaatttaa taatcaatag
    38761 caagtatttt atgtactaaa ggagttttgc tctatataga ctcaatttag taaaattatt
    38821 taataaatat tacagactat aggtaaataa tatttacaaa taaaattaag tttattccct
    38881 tacactataa tatttcttaa ttatattaat tgcaatttcc tttacctttg gccctgtaat
    38941 ttctttattg gaatcatctg atttaatagc aaaataatag gtgtcacctt cacgctctag
    39001 cataccaaca aaccatgcat ccacacgttt atttttttca tcaaatcctg ttccagtttt
    39061 tccatataca tttatgtttt tatcatttat atctattttc ataatatctc ttaaaatatt
    39121 aatatgctct tttttaaagt ttgtatctcc ctcaaatatt tttgccattg tttgcacttg
    39181 ttcttttgga gatatttgta atgaagattc taaccaaaat ccatttaaat gtccctttcc
    39241 attttttaaa tcgccttccc attcgctaat atcgcaattc ccatacttta aatcatctaa
    39301 aatgttttgg acagatttag catcaacttt atctatcaat tttttgtaat accaaacaca
    39361 agactcctta aatgcctctt ctaaactaag atttttattc caatttttat ttggatactc
    39421 tgtaccatca tatcccataa ctgattcttt tgagtttatt accccttttt ctaaaccaat
    39481 taaagttgaa actattttaa aagtagaaca tggtgacctt cttgtttcaa ttaattcttt
    39541 gttatatata ttatattctt tatttttagt attataaaaa atagctcctc cactaatacc
    39601 ttcaaaacaa tcactatagt caaccatatt aattttttct tttttgtttt tatcattgtt
    39661 ttcaattttg gatttattta attcagactt atttaattca gattttatat aattcttatc
    39721 agttttttga tttatatcgt tatgtttttt ccctacataa tacattacca taactacacc
    39781 aaccaataag atagctatcc aaataaaatt cttttttctt ttcataattt atatcatctc
    39841 ccatatttaa atttataacc tactattaaa atagtagaca ttatttgtaa tatactccaa
    39901 tctaggttct acttataaga aacaagacta aatgaatagc tgtatctctt atattttctt
    39961 cacctagtac aattatgttg attaaaccta ttgcgaagat aattaggtaa ctattaataa
    40021 catcctgtcc tccttttaat ttgtgatata gtaattgatt ccacatttaa aacttactat
    40081 tgtaatattt aaatattaca atagtaagtt ttaaatgtca agttagtttg ggaaagttat
    40141 tttaattgta taattgttat tacatttata aaatatggca tgtttaaaat tattttgcta
    40201 ttgggaggat taagataagc agtattataa aagctataaa ttataaaatt taatatataa
    40261 tttatagctt ttacttttac aaatattatt tttattgatt tattaatgaa ttttatttac
    40321 aggttatatt tatataagta aacacttaca taataagtat ataatctaca tatctataag
    40381 ttgagtcaat tcaccagtat atgtcaactt aagtttatgc atagctcgtg tacaagcaat
    40441 atataacaaa ctgcggtcat aatcactata atatgtttta ttatttactg aaggtacaat
    40501 aacttcatca aactctaaac cttttgacat tttaatagaa gttatggata ctccttttgt
    40561 aaagctagaa ctttcagaag atattaagtg aacactatat ttttctctta acgcatcata
    40621 tacagcttta gcgtcattat ctgtctttaa tataatacca agagtcgcat tatcactctt
    40681 tttaaattct tcaatttcta tttttatctt atttatttca tcttgctcgt tattacattt
    40741 taataaagct ggttcttcac catgtcgttc aataggctct aatgaagata tgtcttgaat
    40801 ctttttggcg aaattaataa tctcaaaagt agaacggtaa ctcttattca acataactag
    40861 ttccccatca ttatatagct gtttcatatc atctagtgta tgagtgtgat taggattaac
    40921 caattgtcca aaatctccaa gaatagtctt tttacactta aaaagtaagt ttattacagc
    40981 atattgaata ggtgtgtaat cctgcatttc atcaataaca acatgtctta taatcttatc
    41041 ttcttgtata ccttcatatg cagcatgaat atatataaat gggtatacat ctgaccattc
    41101 aagagttttt tttgttgcca tcacaaacat gtttgatata ttcatttgtt taaagaaatc
    41161 cttatatagt gtaagagtat tttttattgt caacattcca ttcaaacttt taagtatact
    41221 ttttaccttt ggtaaatctt cttccataat attatctgat tcaaatttat aatgaatgtc
    41281 ttcagctacc ttctctaatc tcttcttaac tggatatctg ttatatgcct caaatctact
    41341 ctgtatccag tcacttttag ctgtaaaact tccaaaagtg tagtcttttg gaataaaaat
    41401 cttatttggc atttgtttta tataatcatc aataagtttt acaaaatcaa gtgtagattt
    41461 aaaacgcact ctttcagacc atttagcatc atttatttct aatgggtctt tctcactttc
    41521 aaaattaata actctatcta attgtacctc tgctatattt tcaaaactta attcacataa
    41581 tggctcttct ccaagctcag gaaggacatt ggaaatatag tctccaaaga ctttattagg
    41641 tgataggata attacattat ttgctgatat tttatcttta aatcgataaa gaagaaaagc
    41701 aattctgtgt aatgctatag atgttttccc agaaccagct accccttgaa taatcagtgt
    41761 atcagcttta tcatttctaa taatttgatt ttgttccttt tgtattgttg aaatgattga
    41821 cttcattttt tcatctgaag tgtgactaag ttctttttga agaatatcat cttgtatatt
    41881 aatggaactt tctagtgcat attctaattt tccattttta attttaaatt gtcgttttct
    41941 tgttatttct ccatccaccc atcctattgg agcatcatat ccagcttttc cgatttcata
    42001 atcataaaac atactggcaa ttggagaacg ccagtcaagt attataagct catcttcata
    42061 atcaaatgca aatctaccaa tataatactt agattcatca tccatatctt tcagcctaaa
    42121 atctattcta gcaaagtatg gagaatcttt gattttatta atcttatctc gaacttttac
    42181 cataaaagcc ccatagttat ctatttgttt tagtccttgt tcattttgaa acatttcatg
    42241 tgggtctatt tcaccacgat tttttaccat atacatttta gcgtccatat aatccttatc
    42301 aagcttgtca acaagatttt cagctttctt aaaagcattg tctagcttgt tatttatctc
    42361 tattagatgt gcaatctcat ctggaaaaaa agttaataac tctgcatcat attcacacat
    42421 attatgttta gaattagatg caataatatc gcaatttact acttgtttat tttcagacat
    42481 ttaaatcctc ctttgttaat taagtactta cactgaatca ttatacttaa ttgtgttttg
    42541 gagtttttaa tcattcttgc tatttaactt aaaggaagaa taaatttttg agtaggatat
    42601 ccaaattcca caagcaactc tgcttctgca aaccccaact tctttatcat atctctatgt
    42661 cctgtatcag ctttgtcacc ctctcgaaag gtagtaattg aaatatctgt atctatcaag
    42721 aaatcttcaa taactttctt caaaaacact tgtgcaatgt ctgaattacg atactgtgga
    42781 tgtattccaa aaaaatcaat acttctagtt tctctattaa acaccatatt tgcaatagcg
    42841 acattattaa gttttaatat taaagctctt tcttctaaaa tatactgttc taattgatat
    42901 atatattctt cctgttgcaa attgggaaat ccatctatga ctaatctcac taaattcatc
    42961 cataatggta tgtcagacat acttgcaagt ttaatttctt tttccaactc tagtacattc
    43021 tttgaaaata ggttatcttt tttcaaaaca aatcttagct gcaaaggata aaattcttgt
    43081 tctttcctat atttatttgg agatttttta tacatagctt taaatataga agtgaatgcc
    43141 tgttgacttt catatccagc tatcaatgca atttcaataa ttggtttctt tgaaaatacc
    43201 aataattttg ctgcttctgt caactttctc cgctttatgt aatcatgcat tgttaggcca
    43261 acagaagttg tgaaagttct atgcaggtga tattttgagt aatgaacagc attagcaact
    43321 atatctaaat ccagcttttc tgataaatgc tcctctatat agtcaatagc agttatgaca
    43381 ttaattactt tgtaagacat tgcagcttcc ctccttttag ccatgcaaca ttatatcaat
    43441 tattacttag ttatatttaa tgaatcttgc tattttataa acaaatttgt tgtttaagtt
    43501 ttcaattcat aaatttaata tattactttt tactttctga ttaaagactc taatccttta
    43561 attttcaata acttttcatt tagtaaatct aaaaagttat ttattatttt cttcttatta
    43621 gattcctttt agattcctta attaaatgat aaatatttat attatacgac taaaaacagc
    43681 tttttacaat tatttaatat gattacaaac ttaccctatc ttaaagttta atggggtcct
    43741 gttatgaatc tttttatttt aatttaagct cttcatcagt ttattttata tattgatgta
    43801 tttgatttca tacaaaaaag agtgcttcat gaactaaaaa gttcattttt aaacactctc
    43861 ttttatgtaa ataaatttct attctatttt gaaatattat aatttgactt ataatctgtt
    43921 aataccaaaa ataataaatt gtacgtctaa gaatagattc taattagttg ctcagtagta
    43981 aaatctgttt ttaactaatc ctgctttgta tgttgaacat attctataat tgtaccatct
    44041 ggatgtctca atgtcatatt atatcctgta ggaacttttt tcttatctct tactacaact
    44101 gctccattat ccaatagata acttctccat tcatcaacag aatcaaccat aaaagtagat
    44161 tttgtttcta taaatggttt aagagcatca tcagaaccag ataatagtaa aacatttcct
    44221 atttgcgcta attccaaccc aacttcttta taggaaaaac gcaaagaaca tttttctttt
    44281 aaaagattct cataaaaagg tatggctttt tctatatctt gaatataaaa acgtgttaat
    44341 atatcatata ttttcatatt ttccccctat atatctatat aatattacct ctaaattata
    44401 ccactctaca aattatataa caataaatta agcatagcct tttgagcatc ttaagtagac
    44461 cttaacaata tattggggtt acattagaat acataaatta aatcaccttg atattattta
    44521 ggataaaatt tatgtagtag cagtaaatgt tcttctaatt atcaactaac aaacgataat
    44581 ctttaacttt ctatataatg ggtaacatca ttttcgtaag atattcacta gctggacgat
    44641 tgatatcatt taaatactgg taatatatat cgccatgaag tttatatcca ttgctatttg
    44701 cccatgaaaa taagtcttct aaagtagggt cttgtaattc ataaggtcct aaatcaattg
    44761 cagttattat tttctgtgca ggaacaatct tttgtagaat ctcatttttc ccatctatat
    44821 aagtggctac aggaaaccct acttcaacat ccaattttac taaatccatg ttatgaaaac
    44881 atacaatcgg tgctcctgaa gataaaattc ctctctcctc cagatattta gaaatttttt
    44941 caaaactttg ttttgaaaac tctgaaaatt ctaccataaa gtcaattgtt tttcgtattg
    45001 ccaaaaaaca gtactcagat tgttcagcta ttgttatatt ggatattcta gtcattttat
    45061 tcctccatta ctttattttc atttctaatc tttttatacc aaattatacg aaaattcact
    45121 gtgtaactaa ttatttcata tgaatataaa acataacctc cttccatttc ttatatcgaa
    45181 agtatagcaa aaataatctc atcattcttg tcacacagtg ctcttataat cagaacatac
    45241 ttaaaagact tgcctaattt ttaggcaagt ctaaaagaaa tctttttcta taaaaaattt
    45301 atacaaacaa ttaaaatatc aaacatcaaa atttaaacaa gtttcaggtt catcttctat
    45361 tcttgatatt ttaaacttac atgcaattaa tactaaagat actattggat ttataatatt
    45421 taataaagcg tatggaccat atgttagtgc agatacacct aatgttgctg ttatatacgc
    45481 cccgcatgta ttccatggta ctaatggaga agttaaagtt ccactatctt ctaaagctct
    45541 tgacaacatc ttaggatgta tacctctctt tttatattcc ttattataca ttcttcctgg
    45601 tataactata gatagatatt gttcacctgc tattatattg gtaattgtac aagttaccat
    45661 agtacataat actgttccaa atacaccctt tgctaatctt agtaaagaag atgctactac
    45721 ttcaagcata cctgtttttt ctaaaatacc tccaagagat aaagcgcata ttgttaagga
    45781 tacagtggac atcatattca taatcccacc tttagataat aaagcatcta cctcctgtat
    45841 ttgtgttgac gaaacatatc cattttgtgc tgcatctaat atagtattca tagattctcc
    45901 ttgaaaaact actgcaaaca atactcccaa tacagcacct actataagcc ctggtatagc
    45961 gggaacttta aatacaacta atccaattac tattgctgga gctaataata atactggtga
    46021 taaagtatta aatgtagaat ctaatgtaga cctaattaat tctatttgtt ttatatctag
    46081 tgcttgacct gaatacttca ttccaattac accataaatt actaaacaaa ttaataatga
    46141 tggtatagtc gaatatagca tatattttat atgtgtaaac aaatctgttc ctgccattgc
    46201 tggagctaag ttagtcgttt cagataaagg tgatagttta tctccaaagt aagctccaga
    46261 tattatagaa cctacgatta atccaattgg catacctaaa ctttgaccaa ttcctaaaag
    46321 agctactcct actgtaccca ttgtgctcca agatgaacct gtcgcaagag atactattgc
    46381 acagactaat gttgatgcta ctaaaaaaat atttggtgat aaaattttta gtccccagta
    46441 aatcatacat ggaactactc cacttactat ccaagttcct ataagtacgc ctattataat
    46501 tatgattaag attgcttgca ttgccatctt tatactatta aacatactta attctaactc
    46561 tttccattta aatccaagtc tatatacagc cacaagtcct gctactgctg ctgctcctat
    46621 tagtggtaca tgaggtgatg aaccatacac taatactcct agacttaaaa ataatatcaa
    46681 acaagtaatt ggtatcattg catcaaacag acttgctttt ctacattctc gctctttcat
    46741 aaaatagttt cctcctaatt atttaaacac tacactataa ttttttttga aacatatttg
    46801 ctcgtactag atgacatgat acccccataa gttaataaaa attctaaatt gtcacctaat
    46861 ttataatcat attttgtgtt acttacatct agtatcatgt ggtctgaact tgcccctaat
    46921 atttttatat cagtgtctat tggaattaaa gagtcaatat ttatatcttg tttacctata
    46981 gctatgattg ccctttttaa gattccctta tcttcataaa caggtttatt tctaaaggca
    47041 tcaactccta tttctccaat aggaactgat ggtttttctt tacattcaac tacttggcat
    47101 attaatttaa atgcatcttg atatgttcca tttatatttt caccgtatgc cgtttctcta
    47161 ccaagtagaa tggactcgcc tattctcaaa ttagtaatac cttctggcat attattattt
    47221 atcaacagat gaatcgaact tgaattacct ccagatacta tttctagatt tattccaaat
    47281 ttttcttcca ttctttttgc tatacttacc agtctgccta tattttccct agatggtata
    47341 atagctccat aacaggttaa gtttgtagct ataccaatta tttcaatatt ttttaatctt
    47401 actatctctc ttacattatt aaaaaagtct tcttcataaa agtatccttc tcgtaaatct
    47461 cctaagtcaa acataagaac tatcttatga ataatatttt tactttcaca taattcattt
    47521 aatttcttta ttgttcctaa ttctgagtta aaactaatat cgcaataatt gataacttct
    47581 tctaattcac ttaacattgg gattctaatc aatatcttag gtagatttat atcttgtaaa
    47641 ttttttaagt tttgtattct tgaatctgct atatggtcta ttccttcact acatatttct
    47701 tctactattt ctttttgtgc acaaaatgat ttagtaacaa aagatatctt aatatttctt
    47761 tcatgacaca tctgcgaaat taattttaca ttatgcttta acttttctat atctatttct
    47821 aacctaggat acataatctt tcctcctcaa aattcaaact ttttaacagg agcttaagag
    47881 atgcttcttc atatttttta gataaaacac ccatagatgc cataatatag tcattatcta
    47941 ttaatatctt tgttttttcc tttggaaata gtaattcatt atttttattg tatttgagca
    48001 tattatctaa tatttcaatt ctactaggga gcctagtaag tgctccccct gtaccaacta
    48061 tatatcttac ttctgttaaa tctttccctt ctgcaatttt gacttttcca gttgttccat
    48121 agatatttct tatttttcct gaatgtctta gcatagcttt aacaacagct tcttttgtca
    48181 acctctcaac aaataatatt tcttcttttg attttggtat tggaggataa ttctctatta
    48241 ctgcatcaat atctatagat agttcacttt gtaggttttc tttacctata acttctacta
    48301 tattcttcat atttacatat acacctaaat ccccctcaac acttctcttt gcagtaggtt
    48361 caggattaac caaaatttta ttaatatagt cacttccatc tgtaacagaa tgtacatcag
    48421 tagttgctcc acctacatcc agagttaata aatctccaat atttttatat aaaagtttag
    48481 aagcttccat tacagctcct ggggttggag taatattttc attaaccatt tctttaatgt
    48541 atttcattcc tggtgctgta gttatgtgtt cttcaaatac actttgaatg attcttcttg
    48601 taggttctat attcaataaa tctattttag ggtatacatt ttcagttata taaagcttat
    48661 aattagtatc ttcaaatatt aaccttattt cctcttgatt ttcaacatta ccagcatata
    48721 taactggtat gcctagattc atagaagcta tcatttctgc attataaata gctgtatctc
    48781 tttctccata atcgactcca ccagctatta aaattatgtt tgggtttatt tcttttattt
    48841 tatttaaatc agttctttta attctacctg atgttatttg acgaataaca gctccagccc
    48901 ctaaagctgc ttctttagct gcttttactg tcatatcata gactaatcca tgaacagtca
    48961 tttttaatcc accagctgca ctagaagttg caaacatatc attatactct atatcatcta
    49021 cagataattt attagctaaa tctttaatag cacctgataa gccatttctt acatcgccac
    49081 cttcaaacac tgttgttgga gcttgacctt gacccaaaaa tataggattg ttagtattaa
    49141 tatcgtggaa agcatttacc actgtagtag tacttccaat ttcagctacc aacacatcta
    49201 tttttaaaga aactttgcta ttttccatta tttattactc atttctcttc ttttttcaac
    49261 taagaaagtg gctacatgta tgcctttgct gtttcttcca aatccagcat ctatgccttg
    49321 ttcaacagct atttcaggtg ttacttgtgt tcctccacac gcaatcatta ctttatctct
    49381 tatacctttt tctacacaat aatcgtgtaa ttttttcatg tttttatagt gaatatcatc
    49441 atgacttatt attgtagatg caagtattgc atctgcattc agttcaatcg ctgcatctac
    49501 caatttttct acaggtacag aagtccctag atagtggcat tctatgccat atttttcaat
    49561 acctccatgt tttatatcta ttatttctct taaaccaact gaatgttcat cttctccaac
    49621 cgtagctgaa actattttca taggtttttc ttctatatct gctcttattt cttcatcagt
    49681 tagtacctta ggttcttctg gtattactaa attgtttaaa tctatatcaa acggaactct
    49741 tcctttcact tctattctag tcccttcaga ttcatgcata acttctctac ttatgacctc
    49801 aatttcttgt aagttcattt ttttgacaaa ttccaaagct gcaaactctg ctgttctttt
    49861 atcagtagga atcatcattg ttatcattac aattccatct gcacaccatt ccatttcagg
    49921 cttaatttta gttccatttc tgtactcata tgattctttt agtctatttt ctacattatc
    49981 aaaatcgtca agctcatcaa tatatattat tttgtctgga ttttcaaatg tacatccatc
    50041 tattaacatt gatggattat ctatagcatt ttcatcatat tgagctacat tattgtatcc
    50101 aaagtgagca gttacaggtg ctaaataatc ttcttctctt tcataaacag taccttcacc
    50161 aactccacct tttatttttc tagatattcc atcaccattt ctttctggat aatttccaga
    50221 atcaacaaaa aatccttgtt ccacagattc aaaatatcca ccaacttcag atatttcttc
    50281 catatataat acagctcttt ctttaagttc tcttgctttg tctcttaatt caccgacatc
    50341 tttaagttct atcatatcca taagcccatc cataccaact aaagcttgct ttgctgtatc
    50401 acatgcttct atattgtata tatgccaagg tacatttcta ccttcatcag gtgttatagt
    50461 tgattgtatg tcagctctag ttaatactga tgttaataag tttaatacat gagtaactgt
    50521 tgcttctcta gttgatgatt ccatatattt agtattcatt tgagctctca tcttataatc
    50581 actaaataac tctctaagtg caacagcgta aggtaagtct atttttaaac atggtgctgg
    50641 aggtgctgtt ggtggaactg ttgataagca tatattactt ttatctatac ctattttttc
    50701 tgagaatata gagtttaaag cgtgttgaac cataagttca ggcattacct tccatgcttc
    50761 tctagcagta gcattagcat tatgtgctcc atcaatttga gctatattgg caaaagccat
    50821 tattttcttt gcctcacaag catctacaaa agaccttacc atgtttatat tcctatacag
    50881 aacattatat tgtgggtctt gatgtgctcc attgactcct tcctcagcaa acattactgc
    50941 tacttcagga ccagcaacac cacttacata tgaatggtaa ttaataggtc taccaacttc
    51001 ttcttctata aaatcaagag ccttcctttg agctcttact tgttttcttg ttattggaac
    51061 tccacctata ccttgtggag ttccttctat aagcccatca aaatgtgatt gtccagcagt
    51121 tctgataacc attagatggt cagctccatg atgagctgcc attctcattc ttcttatatc
    51181 atcctcaaat ctaccagaag ctatttcagt agtaataact ggacttggtt gagggtctat
    51241 attattgaaa tacttagatg atggtagccc tacactcttc tttaaaggtt ttgtacagtc
    51301 tttatattta aaaggtccca tttcaagatt ttccaagtgt tctctccaaa cccaacctct
    51361 tcgttttggt ttatatttat ccaaatcttt taatatatag tctatatcca attttttatt
    51421 ttcctttaac atgattctac cccttctcta aataaacatg taacttcatc ccaatattca
    51481 cccttaacta ataacaaacc tgcttctcta accgttatat ttttagattt agccaattta
    51541 taaactacat gccctgctcc tttacctata agacctcttt ccataacccc ttctaaaata
    51601 ggttttactt caagagaaga aaatcccatt ctcaacaaga cagacctttc tattgatggt
    51661 gttgtattct ttttaccaag ttctatcatt ggttctacta tctgggtagc taaactccaa
    51721 aacctttctt ttaactcatc atcactcagt tcttgaagat gttttcttct aacttcaaaa
    51781 tcatcctctc tttttttcat gaacattcct ccattcgtat tgatttaatc gaattttctg
    51841 aatttttatt ttatattaaa ttaaaaaaca ataattacta taaattattt aatacatcaa
    51901 caacaaaatc tcttgaactt tttacttctt ccattaaaaa ttctatatct cgattactta
    51961 gcttatcaat attatcaatg tgattattag atatacaatt ttttataaat gactttctta
    52021 ttttattcat atcaatatca acacatttca ataattctgg tctttctggt aatattaagt
    52081 ttactcctgc aatttcttct cttggatttc caaattttat atctattcca ttttctcttg
    52141 caaaggtaag ttgtggacat atatgtttac ctgcacccgt atattctgtt tcttgtacca
    52201 ctatagcttt atcctcatct agctcttgag ctaaagagaa tgctgctgct aaagatgtat
    52261 ttcctgctgg acctctttct ataccttcta gctgtgccaa taattcagtt gtataaaaaa
    52321 cttctccttg ttttactaat acatatctat ccatatatct aagtggtcta gctgcagacc
    52381 taggtacatc tgacctatca ggccatgtac agtatggtat cccaaaacct gtatgtcctg
    52441 ttgtaaatga ttttttatta aattgattat cactagccat gtgtaatcct tttaaatcta
    52501 cacttgctcc tactacttta gtattaatag aaccagcttt tatcaatcct cttgcagttc
    52561 cagtaagatt accaccacct gcatttgtac aaacaactat atcagggtct tttttatact
    52621 tttctctaaa ttggatagct aactcataac ctaaagtttc tacacctgca attccaaatg
    52681 gtgaatataa tgatgcgtta aaatagcctg tttcttctaa taaaactaag aacgtataaa
    52741 ataactctgg tccaacagtt aactgaacaa cttctgctcc atatgcctca cattttcgcg
    52801 ctttttctat gatttcaggt tgacctacac cattagaatc ataacattct tgaactatta
    52861 tacattttaa tccctgcatt gccgcttgtg atgctacagc tgcaccatag ttaccactgg
    52921 tagctgctat tacaccttta tatcccattt gtttggcatg atatactgca gtagctgctc
    52981 ttcttgcttt aaaactacca gatgcattca ttgcttcatc ttttacaaat attctagctc
    53041 ctttaccttc tttagcacat tttctagcta atttagtcaa atttttaagc tctattaaag
    53101 gagtatttcc aacagcatac tgtgattgaa ttgcttcaat atcttgtaat gtatatcctg
    53161 tttcactcat cattttctca taatcaaacc ctattccctc ttgttcaaaa gaagaataat
    53221 ccaatccgat tgcatttttc attatttcgt tatttcttcc cataacagct tgataactca
    53281 tatctttcat tgatgttgaa ttattcatta tatacacctc caaataatat ttctttagct
    53341 tggattccta tttggagtaa ctctggtata catttaccat aatcatgagt ataatatgga
    53401 tttattttaa gtaaattacc ttttacaagt ctgcctgtaa ttgttttaac ttctactaag
    53461 tcgcctatag aagcatcact ttgtataaaa cctttaaccc acatttctaa ggatactttc
    53521 ttagtatcct ctggaacttg tggagctctt tcttctggag tcaatactat attgtgtata
    53581 ataacccaat cattaatttt agcatccatt ttttcatccc cttattaatt gactattgcc
    53641 ttactaatta atttactgtt attttaaatt aaacattatt ttaccaatta gctaactgtt
    53701 atcttactaa ttagctagtt gctatcttac taattagcct ttgattcttc ttccaattca
    53761 acttctatct gatttcttat atctcccatt attgctctag gtactggtat atccaacata
    53821 gttttaagac ctggtctagc atttattatt aatggaatag agtttactat cattgcataa
    53881 gtacctactc ctccaggtat ttcaggattt atttgtaaat caatgtttgg tatacctttt
    53941 attgatacat agtctcctgt tttaatacct tctgcttctg gtattatctg ttgtggatgc
    54001 tccatttcaa ttaaaacttc tccatttaca tatccatatc cacattgtct acaaccagca
    54061 acatttccag ccaatgcctc tccgtactta gattttctat ctactgtagt cattattggc
    54121 tcttttgttt gttctatctt atctaatttc caacctaatc catcagctat catatttatt
    54181 gattctacaa aacctacatg acctgctata gtcttatctt ctacaccttt tataaattct
    54241 tcccttgtta ctccaacacc ttgttccacc ataacagact ttccaaatgg agataaatca
    54301 tttactctct tagcttttat actagtaact tcttcacaag tacctgaaag tgccaatact
    54361 agtaaatcta atacaaatcc tggatttatt cctgttccaa gtatacttac tccattttcc
    54421 tttgcaactt catccatttt tttagctaaa tctgcatcat cagcttgtgg atatgccatt
    54481 tgttctgctg ttgatataac atttattttt ctatttaata agaaatttat tttatcaaaa
    54541 gcctttttag taaatgaatc agttgctaac aaaacaacat ctacactttt ttctctaaaa
    54601 acttcttcat aatttttatt gataataact tctggtcttt ctcctctttc aattcctaaa
    54661 acatcataca tacttttccc tgaagtactt ctactacaaa cagatactat ttctatacct
    54721 tctttcttta gaatcatatt agccatacct attcccatag ctccaaatcc ccatattcct
    54781 actcttactt ttctcatata tacaccctcc taaaaattta tatattctca ataattagtt
    54841 aaagcataaa tcgtgccaac tttaaaatta aagtaaatat ttattggaac gttgaaacta
    54901 taattatttt attatgtatt ttcataaata aaaaataata tttcttatga gaaataaaaa
    54961 aaagagcaaa atattttgct cttttataat aattttgctc ctctattttg cttttttatt
    55021 ttactttgat tttgtttttt tatcttgctt atttataata ttttgatatt atattttttt
    55081 attttatact gtaaattttg cctattcata cctaaaattg atgcagcttt agttatattg
    55141 taagatgcct tttctaatga ttcatatata tacttttctt ctatctcact gataatctta
    55201 ctaagtgttt tgtcctccaa atcgtttaaa gaataattgt tactctcttt attctcttta
    55261 agagtgtaat agtcgtttag attaatcata cttgtttcta tttgtacctc atcttccatc
    55321 atactcatag tacaataaat tatgttttct agctctctta tgttaccttg ccaatcgtaa
    55381 ttttttaaaa ttttaatagc ttcatctgaa attcctacca cttttttatt taacttttta
    55441 ttatactttg aaataaattt tttgcacaat agaggtatgt cctcttttct atctctaaga
    55501 ggaggaattt ttatatgaat tatgttaagc ctataatata aatcttttcg cattttatgc
    55561 tcgtttaaaa ttacctttgg actttcattt gtcgttgcaa taattcttac atctataggt
    55621 atatccttag ttcctccaac ccttcttaca taaccttctt gtaaaaccct taatagttta
    55681 gcctgtaaca taataggcat ggaatttatc tcatccaata acaatgtccc tttgttagct
    55741 tgttcaaata agcctggcct atctattgct cctgtaaatc ctcccttgct agttccaaaa
    55801 agaatacctt cgaatagtga ttccggcaaa gctgcacaat tttgtgctat aaatggatag
    55861 tttctcctat tacttccata gtgaatggac tggctaaata actctttacc cgttccagtt
    55921 tcaccgtata taaatactga agcatcagac ttgcaagctt tcttagattt agctattgct
    55981 tctttaatca aattactttc ccctaaaata tcatcaaatt cataaccctt tttttgtcta
    56041 atactaactt tattgactaa atttttttta taatttctat ttagtaaatt ttctatcgtt
    56101 gtcatattct ttgatatttc aagtgcccct acaaactcgc ctttaatatc aattggtatt
    56161 gtagtattaa ttgctgttat ctcttttcca tttttatcca gatatttttg aatattgtct
    56221 ttgataactt cccttttttc caaaacttct aatagtgtac tcctgtttat tttcattttg
    56281 ttgactatat caaaaaatga attggttaaa atatcgtgtc tgttcatttt ttccattttt
    56341 tgtacagaat tattgtagat tatagttttc ccgtctttat taacaaaatg taccccttca
    56401 tcaatatttt ccaatatttc attcattatt ttaaaaaata tctcttggtt caactatatc
    56461 accccagtac ctaaatatat aaaaacccaa aaaattaata aaatgttgct attgtattta
    56521 tcttatcata tatttatgat attttttatg tacattatat taatatattt ttaagtatat
    56581 ttaaaatttt atttatatat ctttcattat ggttatatac aatatttgaa ttgtcattaa
    56641 atatgccaat agttttatat attattgatt ttattaaaaa aagagatata caaactaata
    56701 agttgtaatc tctcaaatat aaaaaaacaa taaattagct cattggattt tttagtccat
    56761 aatataatta tagattattc accaaacaat ctatagaaat tgtggtatta atgtttaaat
    56821 aaccaacttt ttctaaaata acctttatag gaatatatga gttcataagt aaagatagcg
    56881 aaataagaaa ccagtttggt atgtaaaatc tagattttta attaaattat caagattata
    56941 tattatagta tcaaaaatag aaaattaaaa ttaaattttt tataataaat tgtatacatt
    57001 ataaattata ttaaattttt aatttaagta atagtatatg taatctttag tcatcttctt
    57061 accagttttt tatccacttt tctaatgaag ttattttttc atatgttaat tcctcttgaa
    57121 ataatgatac taaaagactt tttataaaat tataacttaa aagtttatgt atttttttga
    57181 tatgaattta tagtacttat cttctttaat tgagattgtg tatatttaac taaacattac
    57241 aacaataatt ctatgaaatc aaatcaatta tttacatatt tttttagaac aataataagt
    57301 atatattcac aaaattttgt gttaatattt ttaatttgtg atataataaa agcaaggaaa
    57361 catattttac ttaactttga gtgatgtttc cttcaacaaa ttattttgaa gatttacttt
    57421 tctggaactt tatattaagt tcccagccac tcttagttgg tcgctcagag tggctcttta
    57481 atttatcgta aatgtaactg gctataacac cagttataat actcatcatt agattttcca
    57541 tagttttcac ctcctctcat aagaaagtga agaaacttcc atggaaacac cactcatagc
    57601 tttttcaaat atttattcct tgccatatta attatatcat aaatattgga aacataaaat
    57661 tttaatactt atcgtcttta ttattatttt ttataattaa taattttttt taataataca
    57721 taatataaat ttatatttct tcaataaaaa agacaatctt aattaattgt cttttttaat
    57781 atatatttgg ctaatacatt attttacaca aacattacaa gggtctattt taccttgtga
    57841 cttagcttgt tttaatgtta ctttatttat tgttttactt ctttttagtg tagaacaatt
    57901 ttttgttaga tgatatgatt ttccattagg agttacatat actgtacttt tatcagttaa
    57961 tccaggatta ttagagctag gctcattact tggtttgttc gtattatttg aattagtatc
    58021 ttttacaatg cctgtatttg aatccccaac attattagtt atatttaaac attgttttat
    58081 aacaacatca tcaatatttc caatagcagt tattttactt gcatttttta atatactctt
    58141 attacttcca tttccaacta acactatagg tgttttttgt gcaattgtag aaccaactaa
    58201 agaataaact aaatcagtcc cacttgctat gtaaaattct tttgagccat tataaaattt
    58261 atttattatt tgtttatttg tatcgtatct atctactcca cctattcttg ttgctttagt
    58321 ttcatttatt aacttatcac taatactgac ttttccacca attgcataag tttctaatcc
    58381 atctgtagca aaacttgtag tgtttccatc agttaatact attggagatt tatctctaac
    58441 tgctatagaa gcaacactca tagcatctgg ttcaccttta aaagcattag ttaatattac
    58501 ttttttaaca gcacttacac ttcctatttc ttttgcaact ttatgacttg tatctattct
    58561 atcagttcca cttattctat ttatgcttat ttttttatca cttaatattt tctgaactga
    58621 tgctcctatc gaattttttc ctccgattag atatacttct tttacctttt ctaatctttt
    58681 taatgtttct gaagggattg tatctttctt agttaacaat attggggcat ttttagctcc
    58741 tgacaatcca cttgctgaca atccatcaga taatccattt tcagaattaa taagtattgc
    58801 aatatcataa ttttgtttat ctgctattaa acctgctgtt tcatacttat ttgtaccttt
    58861 tattgaatta atagaactaa gagcgtttga tgttggacaa ctagcaatca ataatgaaac
    58921 agacatccct attgccaata gtgttttgtt taatttcata atgaaatcct cctataaatt
    58981 ttataatatt acttaaatat tataattcta cataaaagaa tattttcctt tatgaaatta
    59041 gtttatattt caaaattttg tcacttttta aatctatata ctaaaaaata gactatttgt
    59101 aacagtctat ttcttagtat atcaaatatt tatttaggtt tacgtttctt tgtactagtt
    59161 tttgtatatg atattccagt tccaggtata ctcaatgtag ctgattttct tccttttgaa
    59221 ttaactgaca ctctagcacc tttaacacca gcacttatac ctacactctt cttacctaaa
    59281 tttaatttga gtcctcctcc tagatttatg cttttcctaa agttaaatcc catagatata
    59341 accttccctt ctatatttta aatatttata cttaaaatta tatttgttat acacttgcca
    59401 tcattggtat atctagcatc tatatctttt tacgtttttt cttcttatat actactccag
    59461 caactacagc tgctgttcca gctccaaccc cataagtagc atttctactt ttctcttctt
    59521 ctcttttttc taaaccttca tcatatacac cttttaactt agtttcaata gacttcattt
    59581 catctggtat actaaaatct tcttcattgt aaccttgatt atatacactt tcttttgctt
    59641 taggtaactt aaccttacca ttatcatatc cttctttaaa ccaattagca tatttaacat
    59701 tacctatagt tgatgtgtca aatctttctc ctttgatagc actctcaaat ccttgagtag
    59761 tgtaatcatt ttttaattgt tcttgtattt cgtcataagc attattataa gcatctataa
    59821 atttagaatc tatgttttct tcaaatgtca ttttttcttt atctttattg ctatcctcta
    59881 tccctttagc tttatattct tctatctttt tagtcttata ttcattgtat ccagttgaat
    59941 atccggtatc ataagcattt tttaaaactt ctttttcata tgtattatta gatttagcac
    60001 ctgtaagccc tagattatat ccagtctctt tagcctcctt ttcttcctct tctaatttag
    60061 ccttaccttt ttcatatcct tctgagtact ttgattcata tgtatcacta taatctccac
    60121 tataatttga tgaactataa tttcctttat acccatcttc atacccttga ttatatcctt
    60181 tttctccaac agacctcttt tgcttttctt cattattaac cgaagttgct gttccagaac
    60241 tgcttcctcc tccagtataa ggacaaccac cattattatg taaatgagct ggataaccac
    60301 cacaatgata gtgataactt cctaatccag atttattttt attatcacga tgacctcctg
    60361 atgaatcagt tcttcctgaa tgagcatacg aaaagctccc tacactaatc atagttatac
    60421 tcattgcaac agctattaac tttttcttaa acataatcta tttcccccta aaatattcta
    60481 tgattttatt atatcagtca atatattatg tttaaaccgt taaaattcga caatgtaaat
    60541 atttgatgaa ttgtatttgt aaataaatct tttagcatat cttgaatatc tgtagttgtt
    60601 ttgacatcat attcttcaat aagtttttta atatttcgtt tttgttaaac ataaaaagcg
    60661 tgcacttttc tttgtatagt gatatttgat attttaatta tcactacttt agaagaatac
    60721 acactttatt ttaaaaaccc tgatactatg ttattagaaa atggtactaa tataaaagat
    60781 atccagcata tactcggaca tgctaaaact tcaacaacta tggatacata tttacatgta
    60841 actaacaaca tgagaaacca gacggtaaat atttttgaaa tcattgtaga ataaatttgc
    60901 cacccaaaaa taattatggt ggcaaatagg tggcaaatct acttttaaga cacactataa
    60961 aagtctgaaa ccctgttatt ctctaataag tttaactaca gtctcacaat gtggcgtatt
    61021 tgggaacata tccatacact taaccatctt aatctcataa ccatacccct taaaatcaac
    61081 caaatcaaca accaaagact taggattaca agaaatataa acaatctcct tagcaccaaa
    61141 tccacaaata tccctaatag catccttatg aatgcctggt ctaggagggt caacaataat
    61201 caaatcaggc ttgtccttta aatccttaac aaccttagcc acatccccag caataaactc
    61261 acaattagta agtccattca acttagcatt ctcattagca gcaacaacag cttcctcaac
    61321 tatctcaata ccatacactt tcttagcagc accagccata acctgtccaa tagacccagt
    61381 accactatac aagtcaaata caactttatc attgtaatct ccaataaaat ccctagcaat
    61441 actataaaga acctcagctc ccttagtatt ggtttggaaa aacgaaaatg gtgaaatctt
    61501 aaacttaaga cctaaaattt cttcttgtat ataatctctt ccatacaata ctcttaactc
    61561 atcacattgg actgcatctg ctaaaccatc attaatagta tgaagtacac ctactaactc
    61621 agcttttaaa tcaatcccta aaagcatatc tttaaactca tacatatcaa aatcttcttg
    61681 agaagaagtt actatattaa ctataatctc attagtgtga atcccttttc taactacaag
    61741 atgtctcaaa tatcctttgt gattcattgt tctataataa ggaagctttt tttcattgaa
    61801 aaactctaca ctagaaacta atatctttga gaagtcttca tcaaccaaca tacactcctc
    61861 aacagtttgt atatctatat gctttccttt tttatgaaga cctaatgtca aaggtccatt
    61921 ttttacttca tctccaaaag tatattccat cttatttcta taatatttgt tttctggact
    61981 tccttctatc cctaaaaact gaaatccaaa taaatcttgc tttaaaaata aatccataac
    62041 ttgtttttct tttatttcta attgtttttc atatggcaca gacaatagtg tacatcctcc
    62101 acactctcta aagtgcttgc aagtttcttc agtttcaagt ggtgagttct ctaataattc
    62161 tatcatctta acttcagctt tcttacttct aactttttta actccagctc tcaccttttg
    62221 accacttatt ccacccttca tatggataac tctatctcca acttggctta aagatgtacc
    62281 accaaattcc attttatcta cttcaaattc tataacatct tttttcttca cagacattcc
    62341 tccaatttac tatagtatct ttattatctt tcttcaatca attttacttc ttcatctgtt
    62401 aactctctat actcacctaa ctctaaactt tcatccaatt ttaaattgcc catagacaat
    62461 ctttttaagt atactacttt tttgcctacg ctttcaaaca ttctttttac ttggtgaaac
    62521 ttaccttcat gtattgtaag ctctatttct gattcatcat cactttttaa tatatttaac
    62581 tgtgatggca tagttttata tccgtcatca agcactacac cttctaaaaa agcttctaca
    62641 tcttcttcag taactactcc atcaattttt gcataataag tcttaggcac atgcttctta
    62701 ggagataaaa ctctatgaga aagctttcca tcattagtta aaactaataa tccctctgtg
    62761 tctttatcta accttccaac aggaaatggt tcaaaagcta agtatgataa atcaattaaa
    62821 tctaatactg ttgggtcata tttatctgta gttgctgata tatatccatc aggtttattc
    62881 atcatcaaat atatatattc tctatatata acttcttctc cattaaataa tatctcatca
    62941 ttttcagtgt ctacttgagt tcctggattt gaaacttcac ttccatttac tactacagac
    63001 ccttgtttac aatacttctt tatttcactt ctgcttccat aacctaaatt tgaaagaatt
    63061 ttatctatac gttgcttttt agccattaaa aatgctctcc attctcataa tatttttctt
    63121 tttcaaatac tgtaaatgct aaatccatac tttctacatc taaattattt cttatactat
    63181 cagttattat tcttgctact atatcttgta cttcttgtcc tctatcaaac caagctactt
    63241 caacaaaagg atatacatct gctattttac catctcttat tgcaactgac tttatacatt
    63301 ctatttcaaa gtagtctctt ggacatttta cagcttcaac taaatcattt atcatttttt
    63361 cacttatttt acatatatca ttttcattaa ttcctcttat ttttatctgt ggcatagttt
    63421 atctccttta ttttaaattt ttagtgaatt atcatccact taattccctt cgataacgtt
    63481 tgaagtggta acttcttggt caagacaact attgttatca gtatctccaa actaataagg
    63541 tagttcctac ccttatagtt agcattatat agctaatttt cctaaattgt ttatattctt
    63601 tattatttta tttaatccta ttgtcttcta tttaacatta tacttgtaat ttatagttat
    63661 tacaatttac tatatacttt ttttgattta acgttataat ataagtgatg ggtaaatttt
    63721 aaaagttaat aggaggagtt taaaatggca ttaattacta caaaagaaat gtttaaaaaa
    63781 gcttacgaag gtggatttgc tataggtgca tttaacataa gtgacttaga acaattacaa
    63841 ggtgttttaa aagctgctaa agctaaaaat tcttatgtta tgatacaagc ttctatgtca
    63901 gctgttaaat atgctggacc tcatacatta gttgaaatgg ttaaggctgc ttctgatgaa
    63961 ataggtgtag atgtagctct tcacttagac catggtccaa atatggatgc tattaaaact
    64021 tgtattgatg ctggtttctc ttcagttatg atagatggtt ctcattttga ctttgaagaa
    64081 aatgttagaa taactaaaga agctgttgaa tatgcacact ctaaaggtgt tgttgttgaa
    64141 gcagaacttg gtgttctagc tggaacagaa gatgatgtta cttctgatgt tcacaagtat
    64201 actcaaccag ctgaggcagt tgagttcgtt gaaagaacag gtgttgattc attagcaata
    64261 gctattggaa cttctcatgg tgctttcaaa ttcaaaggag aagctaaatt aagattcgat
    64321 atactagaag aaatccaaag caaattacca ggtttcccaa tagttcttca tggtgcatct
    64381 gctgttgacc aaaacgctgt tgctacatgt aatgaatttg gtggaaatat agctggtgct
    64441 aaaggtgtac ctgtagatat gttaagaaaa gcatcttcta tggctgtttg taaaataaac
    64501 atggatactg acttaagact agctatgact gctgctatca gaaaattctt agctgaaaat
    64561 ccaaaagaat ttgacccaag aaaatacatt ggtgctggta gagatgctat acaagctgta
    64621 gttgaaagca agatagatga tgttttaggt tctgctaact ctataaacta atataacttt
    64681 taaatattta taaaagaaaa gagatgactt aaagtaatta aatttatttt taagccatct
    64741 cttttaagtt gtataaatta tgtatcttat aatattttaa ttatattgtc tttttaaact
    64801 gacagctaaa cgtgaatatg tccactcttt atctttctat ggatggtaga aggatatata
    64861 cctataactt cagcagcctt tgttattgaa ccatacttat ttatagcctt acttatcatt
    64921 atttggtcca ctattttata tgcatcatta agattcataa ttccatttac cactattggt
    64981 gataaatcat ctgtttcatt atcaatcata tctaaattta tcagcatgtt aaattcatct
    65041 tctccaatta catttttagc tgataatact acaaatcttt caatgatgtt ttttaattct
    65101 cttatgtttc ctggccaaga atattcttct aataactcaa taactttagg cgaaacttct
    65161 acttctctat tgtacttttc attgtaaagt tttaagaaat aatttactaa tggtactata
    65221 tcctcttttc tttctctaag aggaggtatt tttactggaa taacacttaa tctatagtac
    65281 aaatcttgtc taaatttaag gttatttcta aggtcttcat gagaaatatt agtagcactt
    65341 atatatctaa catctatttt tataggctta ctaccaccta ttctagtaat agtattttct
    65401 tgtataaccc taagtaattt tttttgcatc tgcattggta actcacctat ctcatccaag
    65461 aaaatagttc caccattcgc ctcttcaaaa agtccctttt tacctttttt cttagctcca
    65521 gtaaaagaac cttcttcata tccaaaaaac tctgactcta ataattcatt tggtatagct
    65581 ccacagttta tagctataaa gggtttgtct ctccttgaac tatacttata tattgttctt
    65641 gctattattt cttttcctac acctgattct ccatttataa atatagaaga atctgaggct
    65701 gcagctctct taacaacttt ttttatattg tccataatct tactttgact tatatactct
    65761 gtgtcttctg atatatcact atattttatc tgagattcaa gcttaataac ccttgaaata
    65821 tctctccctg ttagtactcc tcctgtaagc tttcccttag aatcccatct tggaactgcc
    65881 gtatatgcaa taagcttccc atctgggtaa acgatatttc tataaatctt tttcttcact
    65941 ttaagcatgt ttaatattat tggttcttca actaatcctt gtctcacaag gtctgttata
    66001 tttctaccaa gtacctcagt tcttttaaaa ggtaatatct catcactgac agtgttcatc
    66061 ttttcaatta ccccatcttt gttaaacaca acaacaactt catctatatg ctctattata
    66121 tcttcaatta ctttatcaga tattagagac ttctcaaata aataaactat attattttca
    66181 ttattattat ctttcatatt gtatatatgt gcagtcatcc ttaactctct gaaagctatt
    66241 ttctttttac tatctgtcag tatttctgtt ttgtcaaaat ttgaatctaa ttcatttata
    66301 tttctaggct tttttatatc tagaaaacta aaaatactat ctattagatg attacagtat
    66361 attatttcgc ctgattcttt acataaaatg gctggatttt ctacatgttc tataagccct
    66421 attaaattat tatccattaa tattcgcacc tttcattaag taatttattg aactacatac
    66481 aaaatttatt gtttgcttac aataaatacc atcagcacat ataatcaact ccttataata
    66541 ttcgtctttt caagtagttt atttcattaa aacgtaacta agatataatt ttaatgatta
    66601 tagtttgtta aaaatttcat tttgctttta attgtatttt atcacatatt tagtaattat
    66661 ttgtctattt aatacaattt aattaaattt aagatttatt taaaaaaaca aagataatcc
    66721 ttacagaata taactcacaa tttgtaagca atatacatat aaggattatc cagattatct
    66781 tgtattataa aattttattc aaacagactt tttaataact gacaaataca cactagcaat
    66841 aacttatcaa agggttaata attatgttac taactaataa gacttattca atcagtaata
    66901 tttatatagt ttgtatctat taagctttta tagcttctaa taaatcatca acgctatcta
    66961 atttttctat aagcattgga actatttcat gtaagtctcc aactactcca tagtcagcga
    67021 tttctaaaat tggagctgct gggtttttgt ttatagcaat tatgaaatct gatgattgca
    67081 tacctgctaa atgttgtatt gctcctgata taccacaagc tatatatagg tttggtttaa
    67141 cagtagttcc tgtttgacct acttggtgag aatggtctat ccatccagca tcaacagccg
    67201 cacgagaaga accaactact ccacctaatt tgtcagctaa tttcttaagc atttcaaatc
    67261 cttctggtcc acctaatcct aaaccacctg atactataac atttgcatct gtaagagata
    67321 ctaaatcttt cttagtttta actgtttcta aaacagtagt tcttatatca tcttgagtta
    67381 ttttgtagtc taatgctata acttcaccag ttcttgtttc gtctttttca gctttatcca
    67441 taacaccagg tctaactgta gacatttgag gtctatggtt tggacaaatg attgtagcca
    67501 ttatgtttcc accaaatgct ggacgagttt gttttatttt cttatcttct gggtctattt
    67561 ctaacttagt acagtcagct gttaatccag ttccaactct tgaagctatt ctaggtgcta
    67621 agtctctacc tatatgagtt gctccgaaaa gcattatttc tggttttatt tcatctattg
    67681 catcttttat tacttttgta tatgcatcag ttgtatattt ttctaaaaga gcatcatctg
    67741 caacataaac tttgtcagct ccaaaagtga ttaattcttt agctaatcca tcaacatctt
    67801 ttcctaataa tattgcacaa agttctgcat ctacttcttt agctaatttt cttccttctc
    67861 ctaataattc tataactact ggagctattt ttccttctct ttgttctgca aatatccata
    67921 cgtttttata agaacttaaa tcttttatat cattcatagt ttgtactcct ccaacttata
    67981 taatgtgctt ttgttttaga ccgattatta ttttactagc tatttcatca gctttacctt
    68041 ctaagatttc tccttttcct cttggttcag gagtaaatga tctaaatact ttagttggtg
    68101 atgcttttaa accaacttct tctttattta catctaaatc atcaattgtc caaactttta
    68161 catcatgttt atatgctttt actattttat caacagacat gtatctaggt gtatttaact
    68221 cttttactgc tgttaaaagt acaggtgtac ttacttttat taattcgtat ccatcttcta
    68281 attgtctttg aactattata tcttttcctt ctattttgaa atcttgtaca tatgtaactt
    68341 gaggaatgtc taatttctct gcaatttgtg gtccaacttg tgcagtatct ccatctattg
    68401 cttgtcttcc tgcaaatatt atgtcatagt cacctacttt agatattccc gctgcaatag
    68461 tatttgatgt agcccaagta tcagctcctc caaatgctct atcacttaat aatattgcat
    68521 catcagcacc catagctaaa cactctctta gcataaagtc tgcttgagga ggtcccattg
    68581 ttataactgt tatagttaca tcatcatgct catctttaat ttttaaagct tcctctaatg
    68641 catttgcatc atctgggttt aatatacttg gaactccatc tcttataaga gtacctgttt
    68701 ctttatttat tcttacttcg ttagtatctg gaacttgttt tacgcaaact aatattttca
    68761 aagtctatac ctccaatttc attagattat ttattatttt aatacgtttg atgaaattac
    68821 cattttttga acttctgatg ttccttcgta tattgatacg attctagcat ctctgtacat
    68881 tctttcgatt tcataatctt ttataaatcc atatccaccg tgaagttgta atgctttata
    68941 agcaacttca tttgcaattt ctgatgcata gtatttagcc atagcagatt cttgagcaac
    69001 tctcattcct gcatctctct tttgtgctgc atcataaact aatcctctag ctgcacaaac
    69061 ttttgtttcc atgtcagcta tagtaaattg agtattttgg aatttagcta taggcttacc
    69121 aaattgaact ctttgttttg tatatttaac agcttcatct aaagcacctt gagctattcc
    69181 tagagctaag gcagcaacac ctattctacc aacttctaga gtacccattg ctatcttaaa
    69241 tccttgacct tcttttccaa gtaagttttc ttttggaact ttaacgtttt caaatattaa
    69301 gtcagaagtt tcagttcctc ttatacccat cttatcttca tgagctcctg ttgagaaacc
    69361 atcccattta ctttctacta taaacgctga tgttcctcta agtcctttac ttctatctgt
    69421 aactgctatt actatagcta catcacagaa tggtccatta gttatgaaag tttttctacc
    69481 atttaatata tagtggtctc caactaattc tgctgttgtt tgttgtccac ctgcatcaga
    69541 accagctcct ggctcagtta aaccaaatgc tcctattaat tcacctgttg ctataccttt
    69601 taagtatttt tgtttttgct cttcagtacc attgtaaagt attggtaatg aagcaagaga
    69661 agaaccagct gtaacaaaag tagctgttga agcacatctt ctagctattt cttccattac
    69721 tatagcgtaa gaaacatatc ctgctccccc accaccatat tcttctggga tattactgct
    69781 tataaatttt gcatcagcta attttttgat taattcctta ggcattacac ctgttttatc
    69841 catttctgct ggtaaagtat ctaattcttt actaacaaaa tctcttactg cttttcttaa
    69901 aagttcttgt tctttgttat ataacatagc ttcctccaat tttcatattt tatagtaaat
    69961 ttattttaat gaacttacgc taaactcatc atctcagcaa aagtttgaat acgagttctg
    70021 gcttgttcat tattctgagt ttgttggtcg atttcaacat ataaagtagg tattccacta
    70081 tcttctatat cttttctaac taaaggataa tcgtattctt ctgggtcaca gaatttcatc
    70141 atacagaaga taacaccatc tatatctttc tttttaactt catctactat aagtgaccca
    70201 cgttttttct tagggtcata agctaatgaa catccttcta tgtttgacca ttgtcttgct
    70261 aatctctcta acgcatcatc acctgctggt acatctgttc tgaattgtct tgtttcttgt
    70321 gctaagtcgt cagctacaac tgatatattg ttgtcttcta aaatgtctaa tatatcttta
    70381 gaatcagcta atatacctgt taataaaact ttctttccag aacagacttc ttctggcata
    70441 gcatttaatt ttgctattaa atctttcact agctcagtat gttcttcttt tctcataaag
    70501 aacccactct taattactaa gcttcttatt gatggtttta tagtattaga atgtttataa
    70561 gctacttcaa caaagtctct catagttttt ctatgttcat tgtaaacttc tatactttca
    70621 tgaatttttg cttcttctat ttcatatcca caaatttctt caagttctct ttttacacct
    70681 ttgtactcac tgattaagta ttttacacca gcttcaagtt ttctattttg tgggtgtact
    70741 aatgatatat attttatatg aggtactgct gatttccagt tttgtcctaa acaaattagt
    70801 gtatcacaca tacctggtat aataactcca gataattcat cataagcacc ttttaatcca
    70861 tattctaaac atgattgcat tattgaacat gcaaatgcag ggaaatattg tttagctaaa
    70921 tctaattctg tttgtcctcc ccatatacca actggaagca ttccagctgc atgtataatt
    70981 tcttctgggc aataaactgg gaaacaacct atagcttttt taccagtttc acttttatat
    71041 ttttttacag ccgcatttgg attttcaact acttctttca ttttagataa aatagcttcc
    71101 attatatctc acctctatta agtttttttc tttcttccat tacttcaact aaaccttgaa
    71161 ttcttgtttc aaattgagca ttagtgaaag ctctagggtc tgcttggtca ccatcaaatc
    71221 cagcatatgg taatccagtt tcttcagctg ctcttctttg catttcatat tgtattaaac
    71281 tcataagttt acagcttctg ttcatatgat agaatgctcc atcacattta ccctctacta
    71341 aagaatcaac tctatatttt gtcatacggt ctaggtttac attgttaaac atagtactat
    71401 atgctactgc cattccatct aaatcattaa cttcatattg taatgcccaa gcatgtgggt
    71461 aaacactacc tgtcatgtta actccaaatt tagctaatgt tttcatcttg tatcctatat
    71521 atggccaaca aggtatacct tccatcatta ttctgtattt ttcttcccct ctgaaagaag
    71581 atttaccagt tttcatgttg tcctctaatt cttctataag taacttaaat gcttctgtag
    71641 tttctttttt acctctagca caaactatta cagccatgta agtaaataag tcaaatccat
    71701 tcattggaga aggagaagaa tctgctggta aactcataga atacttccat agtcttccgt
    71761 tttcagctga tattttcatt acttcttcaa acttcttagg gtcaaatttc tttcctgata
    71821 taatttctag ttgttttata gcttcttcaa attgagcttt aatataatct attcttgatt
    71881 gagtaacttc gtcttcatta ttgaaagttg tatcaatcat tattaaaggt atatctaatt
    71941 ctcttgaaat attttcatac cattttataa cttggttaca tatattgtta cagcaaagta
    72001 ggaaatctgg agccggcata tccaaagctt cacatccacc attttctaaa agaccaaaat
    72061 ttgttcttgc atatgcacat aggtcaatag aatatccttt agattcagct atttcacata
    72121 attctaaaga acctttttta gctgctactc cagctgcttg gttttctgga tataatacgt
    72181 ttaagtcaaa tacttctgct aactcttgag gaaatactga tgttgaccaa cctacaggtc
    72241 ttccttcttc tttagcttta aatgcatttg catattgttc agctaataaa tcattaatta
    72301 ctactctagc ttcttttttt tcagacattt tcatccctct ttttatatat ttttcacttc
    72361 tttttgtgat tcttttgctt catcaaaagc atataacgct gctcctaaag caccagttaa
    72421 ttgaggtata tcaggtacaa taatttctgt gttgatttct cttgccatag ctcttacaat
    72481 accactattt ctagcaactc caccaaccat aactacattt ctttgtactc ctattctttt
    72541 tactaggcta gaaactctct ttgctactga agtatgaata cctgccacta tatcttcaat
    72601 ttttgcattt tcagataaat gtgatataac ctcagactct gcaaatactg tacatgtact
    72661 gcttattgat acttcatttt gagaattcat agatatactt ccgagttcag atacatcaac
    72721 ctctattatt tttgccatta catctaaaaa tcttcctgta cctgcagcac atttgtcatt
    72781 cataagaaag tttaatagtc ttccattatt atctaatttt aatacctttg catcttgacc
    72841 acctatgtca ataatggttc ttgtctctgg aattatgaaa tttacccctc tagcatgaca
    72901 gcttaattca cttatttgct tatcagcatc tgaatagttc attcttccat atcctgtaac
    72961 tacaactttt ttaatatctt ctcttgcaag acctgtcttg ccatataatt tttctaaaac
    73021 tcttgatggt ccagtagtcc cagtaccaga ggatattgtt tcagaagcta caatatcttc
    73081 cccattcttt aagattactc cctttgatgc agttgaacct atatctaatc ccattgtgta
    73141 catctttagc attctccttt taaaaaatct agaattacta attaatatct tacaacttta
    73201 ctatctttaa agttatttat tttctcttca tcgtagccta aagattttaa tacttctaca
    73261 gtatgttgac ctacttttgg tgctggtgta tattctttaa ttccttcatt tctaaacata
    73321 actggagtat taactaagac acctgtattt ccgctatcgt atgttttctt aaataagaag
    73381 tcatttgccc aagcttgttc gtcatctaat aaatcttcac agctttgaat tttttcaaat
    73441 ggtaagtctg cttcttctaa taaagctgac cactcgtcta atgttttttc taacatagct
    73501 tctccaacta tcttaactaa atcttcaaca tgattaacca ttgaatctat gttattatat
    73561 ctatcgtctt ctaatatata ttctctattt ataaccttac agaatttgcc taaccacttg
    73621 ttgtattgta ttaaagctaa ttgaatccat cttccatctt tacatttata tgtagtcatt
    73681 aatgggctgt ttggattttc tcttgataaa ggcatttcat ttccgtattg tgctgttgtt
    73741 atcattgttc ccattccata tatagctgta tggaaaagac ttactgttac tctctcacct
    73801 ttaccagttt gagctttttt atgtaatgct gctaaacttc ctgctgctag tgctagacct
    73861 gcatagtggt caccaaatcc tgctgctgta tttgctggag atgttccttt ttccataaca
    73921 gattggctaa ctcctcctct tgcgaagtat gcagtatagt caaatcctgg tttatctttt
    73981 aaaggtcctt tttcaccata tcctaatatt tgagagaata ttaatcctgg atacttatct
    74041 tttatttggt cataagctat acccattttt tctaatgctt gaactctaac attagttaca
    74101 aatatgtctg cttctgataa taatttatgt aatatttcta ctccttcttt tgattttaca
    74161 ttaatactta cacccttttt atttccattt tctaattcaa acatagggtt ttcatcatct
    74221 gatgctggag atttaaatgt tccacccata actcttattc catcaccttc tataggttca
    74281 atcttaataa cctctgcacc ccagtcacct aacatttttg cacaacatgg tgctgcgatg
    74341 aaacttgaaa gttctactac tttaactcct tctaaaagca taacgttttc ctccttaata
    74401 gtatcaatta taaaatttcg attaaatcac tcataaaata cttttttctg atattaactg
    74461 tctgatgtca aagttcctaa tcttatctaa aataacttaa aaattattaa aattattttt
    74521 tattgtttta ttgtcttaca cctatattgt taagcattta tcgtgccaac tttatattta
    74581 atcaaaatat cgcttgattt gaatgttttt taacaatatg caattgaata atctttttca
    74641 tatcgtggca tcttgccact atccattgca ttttgctatt ctttctatgc ttataaaagt
    74701 tttttttata tattttttta tgaaaaagct tgacatttca aaaaaagttt tcattgctaa
    74761 actcaaaaac acatgttatc attgtaatta atcagcaagt tagttaacta atttcaaact
    74821 tagataattt tttaataata tttaatctaa aaaataacaa tttctttgat aaattttaga
    74881 gtaattatta cattaaataa aaaattacta aatatcaaaa taacacaggg aaaacaattt
    74941 caaaactaaa tttttaacct taaaaatttt gtataaaaaa tataacctta tatgctacat
    75001 attatttcta aatgaaaaat taccataata atttaataat tacaggaggg tattgatatg
    75061 aaaatactag tatttggagc acgcgattat gaagaaccag taataaaaaa atggtctgaa
    75121 gaacataagg atgttcaagt ggatatttat cctgaaaaca tgactgaaga aaatgtagtt
    75181 aaagctaaag ggtatgatgg tatatctata caacaaacta actatataga taatccttat
    75241 atttatgaaa ctttaaaaga tgctggggtt aaagttatag cttcaagaac tgcaggggtt
    75301 gacatgatac attttgattt agttaatgaa aatggactta tcgttacaaa cgttccttct
    75361 tattcaccta atgcaatagc tgaattagct gttactcaag ctatgaacct tttaagaaag
    75421 actcctctag taaagaaaaa agtctgtgaa ggtgattacc gttggatagc tgaacttctt
    75481 ggaacagaag ttagatctat tacagttggt gttataggta caggaaaaat aggtgctact
    75541 tctgcaaaat tattcaaagg cctaggagct aatgtaattg catttgacca atatccaaat
    75601 agtgatttaa atgatatatt aacttacaaa gattctttag aagaccttct aaaagaagct
    75661 gaccttataa cattacatac tcctttactt gaaggaacaa aacatatgat aaataaagat
    75721 actctagcta taatgaagga tggagcttac atagtaaata ctggccgtgg tggtttaatt
    75781 aatacagggg atttaataga agcactagag tcaggaaaaa ttagagctgc tgcccttgat
    75841 acatttgaaa ctgaaggatt gttcttaaac aaaaaaatga atcctggaga attaactgac
    75901 ccagaaataa ataaacttct ttctatggaa caagttatat tcactcatca ccttggtttc
    75961 ttcactagta cagcgattga aaatatagtt tattctagtt taagtagtgc tgtagaagtt
    76021 ataaaaacag gaactgctac taatagagta aattagtatt ttataaatat attttttcat
    76081 taattagcta ttatctaaca aaatagcctt taatttccca aatataagag agtcagctca
    76141 gtatatattg agtagactct cttatattat tttttatatt aaacttgtac tcttcttatt
    76201 cataccaaat taaatttata ttaacttact ctaactactc ctactctata cattttacct
    76261 atttttactt ttctaattat atacatttga atgggtacaa tctgtatttt acaaaaaaac
    76321 acctaacaaa ctatgaaaat tgtatgatta atattaatat atttataaga aaacataaca
    76381 attatgttag ctctggattt ttagggaggg agtatattgg aaaaaatgaa taaagttact
    76441 tctaaaaaaa ctacctatat tgttacttca gcattatttg catccataat atgcctgaca
    76501 atagcatata tattacatat tccagttggt ggaaacaatg gatatgttca tataggagat
    76561 gcttttattt atctagctgc aactattttg ccaacaaact atgctatagc tgcttctgca
    76621 attggtgctg gtctagctga tttatctaca ggtgctgcta tctgggtaat accaactata
    76681 atcataaaac caatacttgt attatttttc acttctaaaa gtgacaagat aataaataag
    76741 agaaatatag ttgcttcggt tgtagcaggt atagtaggat tagttttata catgtttgct
    76801 gaaggtataa ttattggaag ttttacaagt gcatttgtaa tgagcttact tggcttatta
    76861 cagccaatag gaagttttat tgtttttata atcttaggta tggcacttga taaacttgat
    76921 tttaaaaaac gttattttaa ttaagaattt aaatttatgg agggaaaatt atgaatatct
    76981 tatatacaat tgaaaatagt atctatgtaa atataactaa tacatgtcca tgtagttgtg
    77041 ttttttgtat aagaaacgaa aaagatgaag ttgcaaatag tggtagttta tggttggagc
    77101 atgagccaag tgtagatgaa gtaaaagaag ccttcaataa atacaattta gacgactatg
    77161 atgaaatcgt attttgtgga tatggcgaac cattaatgag aataaatgaa ttgatagagg
    77221 tagcaaagtt tataaaagaa aaaagtagca taaagataag aataaataca aatggtctaa
    77281 gtgatttaat acataacaaa aaaacagcta ttctgttaaa aaatgttata gatgcagtat
    77341 caataagtct taatgcccca aataaagaag cttataatag agttactcaa ccaaagtttg
    77401 gagaaaaatc atttgattat atgttagatt ttgcaagaga ttgcaaaaaa tatataaaag
    77461 aagtagcttt ttcagtagta gatgaaatat ctccagaaga aatagaagaa tctaaacaac
    77521 tggcaaaaaa acttgatata ccattaaggg ttagacataa gaattagcaa gtaaaattat
    77581 aaaacattaa gaatcacctg aatggtcttt caggtgattc ttcctcttgt attaacattt
    77641 tacaaaatag atttcatacc acactaggaa tgtgtaaatc atccaaatct ttctccaatt
    77701 atcagagttt ccactaatgt agtcattaaa aatctcatta atctcatcta tgttaaagaa
    77761 tttatctgct atctcactat tgaatttatc tcggatatcc ttattatatt ggtcatcagc
    77821 catccatata cgaattggca caataaatcc taatttattt ctaaaagcaa tctcttctgg
    77881 taatgttttt gatgcagctg tacgaaaggc aattttattc tcttttcctt tcactttata
    77941 ttctgatggt attctggatg caatatcaaa tattcttgta tctgtaagag gcattctgac
    78001 ttccaatcct actgcagtac tcattttatc tatattaaaa taaatatctc cttccaacca
    78061 tatttgaata tctacatttg acatgttagt aagtgtatct agttcttctg tttcttcata
    78121 aattcctttt accacttcaa taggaagcac atcaggattg tatttcttaa gaatttttct
    78181 tttctcaccc tcattcataa tgtttgtatt tccaatataa aatgtcttca aattctctcc
    78241 ataacactct gccttatggt atatattata tccaccaaaa aactcatctg ctccttctcc
    78301 agagtaacag atatttgtgt tttcagctgc tgccttgcat ccaatagcaa aaacgatagc
    78361 agatgcatct ccagttggtt gctccatatg gtacattaca taaggtactg acgcaaaata
    78421 ctcttcaggt gtaattatat atctcgaatt tttacaccca agaatattag ctgtctgttg
    78481 tgctaatttt gattcatcaa aacgctcttc ctcataacca catgaacctg ttttttctat
    78541 atctgacatt gccaatatat aagatgaatc aacacctcct gataggaata actctgcagt
    78601 ttcattctct gattttacct ctggcataat tttctgaagt gttgtatgaa tttcatccgt
    78661 ccattcctca atagacttgc tgtggtcagg atgaaattca ggtttccaat aacgaccaat
    78721 acatactgtt ttattctgat agacaaggta atgtcctggc ataagcttct ttactccacg
    78781 gaagaatgta ttttcacctg ctacatatgt gaaagacata taaatctgta acatgtcttc
    78841 atttaactct ttcacaaatc ctggttgctc cataatctta cgaatagatg aaccatagag
    78901 aagcttccca ttttcagtct cataataata gaaaggtttt accccaaact ggtctcttag
    78961 gcagaagagt ttcttttcca cagtatccca taatgcaaaa gcaaacattc catgcatgtg
    79021 atttgccata tcatatcccc atgtcttata tgcttccact aaaattgctc gttcacgctc
    79081 atctctacat aatgaagaat cgattccaag ttcttcacaa agaactttcc agtttcgaat
    79141 atgcccattg tattctagaa tttttatcat atatgtgtct tttcgtgtta aatacttttc
    79201 ttctaaattt atcatatgtg tatcctttcg tattaaaaca tttaacttct aaatttatta
    79261 aatgtttata tatatttatt cacttataat cactgaaaaa tcgacttttt tcaaagtaaa
    79321 ttctttttga attagtacta atctgctctt tattaatggc ataaatatga ttatcaagta
    79381 ttatcagtgt tataacattg aattttttat tcttcataaa tattgccccc tttatattac
    79441 caactaaata taatatatct tatgttactt acatattctt taagaaattc tgaagatttt
    79501 ataaagtttt ttgtattata attaattaaa aataaaattc tagttataaa acatattttc
    79561 cattaaacaa aaaaatagtt aaaataaatt cataaccaca taaacttatt ttaactattt
    79621 gtatatttta attataaata ttaacttaaa tttttaacag gatacactca taaaataaac
    79681 ataatgaaca acaaaataat atgtctcagt ttctttatat actttacctt ctttcaattt
    79741 tctaccatgt agacgtataa gataatatta gtaattcact ctattgctta actcgtgcga
    79801 tatggacaac caagaaagct atttcctcat ttgttaactt ttttccatat ttcttttcta
    79861 aaaaatctct aacttttaat gcaattaaca tttcttttgg atttgacctt ttcatttgat
    79921 taaataataa atcatcacca ctgcttaaca tactatctga aaaaaatctt tccacaaaaa
    79981 attttatatg tgttataaat ctcatataat gcatactctt tttatctaag gttctattca
    80041 aagaaaaaac aaaaatatta attatttctc caattacttt ggcatactta atcgtatcat
    80101 atgaatttcc atctgaagcc atagcatttg caaaatggaa agcaatgtta gctgcttctt
    80161 cctctggtaa ttgaatgccc aatctctcct ctaccatata aattgcaacc attccaacct
    80221 taaactcatt tggataataa ttttttattt cccaaaatac tcgatttgta atttttattc
    80281 ctttacgcat cctttcaatt gcaaagttaa aatggtctgc taatattaag tataagtttt
    80341 tattaaaaga tgagttcaat aacttttctg cctctactat tatttcctgt gttatcttta
    80401 aaatgtcgac aggaatatca tccattaatt ctaaaaattg ttttgatttt gtattttcaa
    80461 cagggacaaa catttgatta tcattggaac cacaaatata ttctcctgtt tttttaccat
    80521 atccaattcc tttccctagc aaaataaatt cattatcctt tgtgtcatga actaaaacaa
    80581 cgctcgagtt caaaactttc tttattatgt agttcatttt atttgctcac cttctattgg
    80641 tcatttaaaa tctatactat tactttcaat taccttttta taccaataaa aactatcttt
    80701 cttatatcga ttatatgtcc cctttccata atcatcagca tccacataaa tatatccata
    80761 acgttttgac atttgtttcg ttgattcact gaccaaatca atacaacccc atgaagtata
    80821 tccccaaagt tcaacaccat cttcaataat cgcatctaac atacatttaa agtgttcttt
    80881 taaataatta attctatatt ggtcatgaac ttttttatct tcagttaaaa tatctttggc
    80941 tcccaatcca ttttcaacta taaataaagg ctttctgtat ctatcatata attcaatcaa
    81001 agatatacgt agacctattg aatcaatttg ccaaccccat tcactcattt ctaaataagg
    81061 attttttaca gctaataacg tattcccagg tgtaatatct aatccagttg tatcagctgc
    81121 ctcacaagaa gacatatagt aagagaatga aataaaatct actggatact ttttcataat
    81181 ttcatcatca tgttcttctt ttactatttg aatgttatta tttttaaaat acgacagtaa
    81241 atatactgga tactcaccaa aaacctgcgt atcactatat gcataaatac ttctcatttt
    81301 tcgttgagtt gccaaaacat cttctggtct acatgtgtat ggataatacg ttaattttgt
    81361 taacatacac cctacttttg aatttggaat aatttcatga caaatttttg ttgcaagggc
    81421 actagctaca aattgatgat gcatagcttg aaaaataact tcctcaaagt ttttatcctt
    81481 aaaacggtct cgaactaaac caccagtagt gtacggatga cgaatcatag aatcaacttc
    81541 attaaatgta agccaatatt tcactttgtt tttatatctt tcacagatag tttctacata
    81601 cctaacaaac atattgataa cttgtcgtga ataccatcca tcatagttta aaacgatatt
    81661 taatggtggt tcataatgtg acatagtaac aagtggttca attccataac ttatcaactc
    81721 atcaaataca tcatcataaa actgtaaacc ttcttcattt ggctctttat catctccatt
    81781 tggaaaaata cgagaccaag caatactcat tcgatatgtc ttaaatccca tttctgccat
    81841 tagagcaata tcttctttat agtgatgata aaaatcacta ccatgacgtt ttggataatt
    81901 tacttcatct tcaggatgtg ctaatccttc ttctatatct tttgttgtga tttcattatt
    81961 agatttataa tctttcacat ctgcatcaaa gtgtgccttt gctacatctg atacagacca
    82021 ccctttacca cctaaattcc aaccaccttc aaattgatta gcagctgtag ctcctcccca
    82081 aagaaatcct tctggaaact ttctcatatt tatattcctc cctttacatc aaacaagata
    82141 cttccttttt ttacattgcc ataagactgg tttaacactt tataagcata atctgctcca
    82201 ttattgttta caatcataac agttgaatct aaattagcat gtgagatttt gtctaaatca
    82261 aactgaatta ataaatctcc ttcttttaca ttatcgcctg tcttaacaaa tgttttaaat
    82321 ccatctccat tcatacttac agtatttatt ccaatatgaa tcaaaatctc agccccattt
    82381 tttgttctta aaccaattgc atgttttgtt tcaaataaca tcacaacttc tgaatcacaa
    82441 ggtgcgtata aatttccatt ggtcggtata attgcaactc catctcccaa agtcttactt
    82501 gcaaatagtt catcattaac cttacttaaa tctattactt ttccttctac tggagttact
    82561 aagatattta cttctttttc ttcttctagc tcttcttcaa caacatctcc aattgatgac
    82621 tctactgtat ttgtatcttc cttccaaata atcagtgtaa taataaacga gcctaatatt
    82681 gcaataacaa aaccaatact tgcaaaaatc aaattgtttc cattgtttgg gtcaataaac
    82741 atactcatac tggcaagccc tggtccaaca attacaaatc cttttactgc aaataatcct
    82801 aaaaatgtac cagaaattgc acttgagaat acaacaccta acattgctct tttatgttgt
    82861 aaagtaatac catataaagc tggctctgta attcccatca aggcagaaat tcctgcagat
    82921 aatgctgttt gttttaatgt ttcatctttt gttcgcaagg ctactgcaaa acaagcacca
    82981 ctttcagaaa tattgtgggc taatgaagat gtcatatata aagcttcata acccaacttt
    83041 ccaattgtat taattgaata aggtattagt gctttgtgca ttcctgttgc aaccataaat
    83101 ggaagaaaag cagcaagtaa tcctacaact aagaatccca ttttgttata taagaataaa
    83161 ataatggttg taaaaattgt accaacgtta tatcctaaag gacctaaaat agttagagta
    83221 attggaacag taattgccaa agacatcata ggaacaaaga aagttcgaat tggttttggt
    83281 gaatacttgt taaaaatttt ctccattgtt gccaagaaag acacacataa gatagccggg
    83341 aaaacctgtg cattataggc aatgtttgga attgtaaatc caaatagttc gacaccttca
    83401 cttaaagcag ttgttgttgc tggaagcaat aagtatccta cagcggcaat agctactaaa
    83461 cgattacatt tcaatacatt ggcagtagtt acagctacca taagaggtag gaaatagaat
    83521 gttgcatctg aaatagcaac taataatgta tatatagtag aatctgattt taaaatatta
    83581 aacattgcta ataacatcaa cagtgatttt aaaataccag ctcctgcaat agcaaaaatc
    83641 agtggttgaa aaatattaat aataaattct ataaatcttg ttcctaagtt tattttttct
    83701 tcagttttta cagtactatc atttgtatct aaagggcaaa cttttaaaat ttcatcatac
    83761 acatcaacaa cactatttcc aatgacaact tgaaattgtg ccccattaac tatactcata
    83821 acaccttgta ctttttttaa agcatcctga ttgactttac ttctatcaat caacttaaag
    83881 cgtagtctag ttgaacagtg ttctaaagct aaaatatttt ttgaaccacc aacttgttca
    83941 ataatgtcaa tggcagtttt tttataattc atcttgtaat ctccttctcc ataatttttt
    84001 atgaatggcc attcaagatg caaaaaaggc agaacctata taaacacctt gaaaaatcaa
    84061 agcaatatat tcgatcctgc ctgcattacc agtaacatgt cttctattta tactattttg
    84121 tattattata ttaacatttg cctaaaagaa ttgtcaatac ttttttaaat tttctgatac
    84181 taactaatag cacctttata attcattttt tatatcaatt aaagtaacag tagccaccca
    84241 ccaattagta tcaaaattga acctggtatt ttttctttta tattttcttt gaatataaaa
    84301 tgagcaagta ttaaagttat tatcatagat acttgagaaa atggctctgc tatactaagt
    84361 tctagattat ttaaagcaat taataatgct aaataagaat atccattaat agcaccactt
    84421 aaaattgaaa gccccttttt attactaaaa atctcacaaa ttattttttg tttcttttta
    84481 aatgctaaaa agataaataa atttaaacct acgaaaaaat acagtatagt tgaatataat
    84541 ataggagata cttgtacaaa aaaagcctta tccaatactc ttcctactga ctgcaaaaat
    84601 atgtataaaa acattaatct acatggtaaa ttgttaaaaa ttacagagac attctttaaa
    84661 aaagagctta ctttttttaa tataaacact ccaccaatca taattatgat tcctgcaact
    84721 tttgctaaac ttaaaccttc acctaaaaat ataactgata aaagcagtaa aaacaatgaa
    84781 tttaaactat ttattggagt aacaagtgaa acttccccag ttgctaaaga cgttacatac
    84841 gctactgaac caattgaata gactaaacta cttatataac atggtattaa aaacgaccaa
    84901 tcactaactc tatccattat gctaaatgga agtaaacata ctccccctat aaagaaaaat
    84961 agaaatgatg aagctatatt tttataaata tctccttctt catcacctaa taatcttaca
    85021 actactcttt caaaagctaa tagcactact ctaattaata atgcaaaata agataatatc
    85081 atttttgacc tcgcttaaaa attaatccga cttattgtta tattaactgt ataaaactac
    85141 catataggta agtcttttgg attttttaat attttatgtt taaatacagg tacattaagt
    85201 ttttcaccta gtttacgaca ttgctcttta taggtacctt ttaatttatc atgaaaaact
    85261 atacaatcaa ttcctccttc aatactattt atacactttt ctagtttctc aaatccagat
    85321 tcatcatcat acattccact tacaatccat tgatttggca atacatgtcc aattgatatg
    85381 ttatattctt tattttttat aatatctgag aaagatttct caaaatgtac ccctccaaca
    85441 cataacaaag tcttcaaagg ttcatcacaa tcaaatactc taattaatga ttttgccaat
    85501 acctgtattg ctatactatt attaaaacta tcactactac ttcctatctc aatatccaac
    85561 ataggtacag aatattctgt aattaattta gattcttcac catatgttgt tccagaccag
    85621 tgagttgctt ctgttaatgt agtaaattca tcaagtagat tttcattttt tatatcctca
    85681 atagcattga ttagattttt aaagtatctt ggatttgaat ttccaaattc tcctgttgga
    85741 acatctccaa ttgtatgagc tgttaggata tgttctggag cattttctcc ctcatgccaa
    85801 tttacaactc ctgcaaaatc ataatctcta aaatgtctat ttaaaattgg aagataatat
    85861 ttataattat gacttattac atcttttgtt tttacaaaat gaaataagtt attgttttta
    85921 tccttaaact ctaatacaaa attatcatca ataacaatat cagtttgatt taaatccatt
    85981 atttcttcac aacattttat cacattactg gctactgggt ctttctttaa atcactgcaa
    86041 aagaaaaaaa ctgctttttt attattcatc cataaatcac actcctataa cttaaatata
    86101 atatatcttc atacctaaaa tcatctaaat atcactctaa ttccattaaa ttatttatat
    86161 ataatatact accatactca ttttagctat acctttgcct gagtttctat atatatgtga
    86221 tacatcagct ttaaatctta tagaatttcc actagataca atgtaatctt ctccatttat
    86281 tttaatggtt acttcgccac taaaaacagt tataaactct tgtgttcctg gaagttcagc
    86341 atttgaatct aaatttccac cttcttctat ttcaatcata aatatctcaa atcttctttt
    86401 ggagtcaaat ggaaatattg gataacttat atactttcca ttatcttcaa taaaatggtc
    86461 tatatcactt ttttgaatca attctatgtc actttcctgc ctctccatca atgatgtaaa
    86521 tgagattttt agcccattag ttattttctt caaagtagat atagtaggat ttacctcaca
    86581 cttttcaatt tgagatagca tactcttact tacaccacta agttgtgcaa tcttgtctaa
    86641 actaagatgt ttttctttcc ttatcttttt taaattttca gcaattattt catttaaact
    86701 ttgcataaat accccctaat acatactaat ataagataaa ttattttgat tattaaataa
    86761 acttagtaat ttaatagaaa ctttttatcc attataatgt acattatgtt taatatacat
    86821 tacttttttt agaatgtaaa tagttttctg aaattttgtg aaaatgaata aataaaaaac
    86881 tagtaaccta tatttttaca aggttactag cttttattat aataatcttt cattttaact
    86941 ataaaactta gatgcaccta taagctgtct cttagaaaca atcttagcta ggtttgctaa
    87001 tgaagaaatt tttatatctt taaaagaaac taaaaataca aacttaaaat ctgtaaattc
    87061 ttgatttata ttgtatatat caaaataaca tctcaaatta tcaaataagt aattatcctg
    87121 taagtctgct tctatctcat cagtagcatc ttttaaatac gctcttacat cttcaaataa
    87181 aacactgaaa taagactcat ctatttcttc acctaactct tccaatattt cttctatatc
    87241 taaatcatcc atatcaaaag aatttcctgt caactggcaa tcaaatacca atatattttc
    87301 ttgatttata gtatttgata tatcttgtac atattcgaag tctggacgta attctaaaat
    87361 gtcttttatt tcactgctct ttacatggat ttttcctttt ctattttcaa tttttaaatc
    87421 tatcatatgc tccccctttc aatctacaaa tctttaaata ccttgtttta taatcttttc
    87481 aatatctatc caattactaa ctctaactat attttgatgt ttaacatctt tattatagtt
    87541 agtatccaga agtattactt taacaccatc atcagctagt tgcactgagt ttaaaggatt
    87601 atcttctata aatatgtcac aactcagttc tcttgccttt tcaactttat aatcacttcc
    87661 taataagtaa acatctatat ctgaaaatcc ttgtctcgat agccaatttt tagttacatc
    87721 agttaaacac tcatgtctag ccgttacaaa agataaatta tgtcctttag ataatgtgct
    87781 aattacctct gtagcaccct ctacaatctt tgcttcatca tatgagtgta tatacttatt
    87841 attaaactcc gcatacacat ctcttattcc cgaaccatac aattcttccc aattatgtgt
    87901 tatacactct gcttcagtta tatttttatt aaagatatca tttaggtatg gaagaaaatg
    87961 ataagggctt gttattgttc catctatatc aatacatata ttcaatttgt tcatttttac
    88021 ctccatgtaa catttattga tttgattaat caaatattat agcacagctt taattataaa
    88081 tcaaaactct ggatatgact atacctatat aataccaaaa agcttgcata tttaagcaag
    88141 cttttcgtaa attttacatt tttaactaat atataagttt ttctaaggtt ggttccactc
    88201 caaattgtga tttcagttct ttatattctt ttaatgcttt gtcattattc gttttagttt
    88261 ttatcgctct tatcattaaa ttttttggtg tatcaagtgg agatatgtat tctactacag
    88321 aagtatcata tccattgccc tccaataaca atgttcttaa accatcagtt attaaatctg
    88381 caaatctagc tttaaataca ccatgtttta atattggttc catagcttca tatctatatt
    88441 gccctaatag ctccttatga caacatggta ctactactat agcttcagat tttgctctaa
    88501 ttcctagacc tattgccata tctgtagccg tatcacaagc atgtagactt attacaaggt
    88561 caacatccct attaggtgta taattagtca aatcctcttt tataaatgac atatttttat
    88621 aacccaagtt tttagccata ttttttgatg cttctataac tacatctgaa taatctattc
    88681 ctataaaata acagtttttc ttcaatactt cttttatata aaaatttaag acaaagctta
    88741 agtaggattt tccacaagca caatccaaga tagttataca gtctttatcc tttatttctt
    88801 ttaaaatact atctatcaat tcaacaaaat ggtctatctg attgtatttt cttattttat
    88861 cattttttat cttaccatct tttgtaagta ctccaatttc ttttaaaagt gcatttgctt
    88921 gtcctacttt tacataataa tctctgtttt ttatttgaga tgccgtaaat tcatctattt
    88981 taggtacttc ttccttatta tctaaatatt ttacatttac cttcttattg tctccttcaa
    89041 ttacaacaat agttcctcgc tcaacatatt taaatactaa tccatcataa ttttctgcct
    89101 ctttagaaat attcttaagc aactcattaa acgtatataa atctgatttt cctttaaaat
    89161 taaatttata tttattatct tcctctattg caattccttt aaactctttt cttccagatt
    89221 taaaaatcac ctctaactca ataaaaaaat ccctattatc aaggtttctt tgagtaatcc
    89281 ccataaaaaa catatttagt tttcctatac tctgtttatt catcataatc tcccttttaa
    89341 cttatatcct taaatcttat taattaatat tatttgtttc tgaattattt atttcttctt
    89401 ttaaatcgtt caatctattt ttaaaacttt ctatctgctt atctgataaa tcaagatatt
    89461 ctgttatctt ccctatatat ttagggcttt tagtatttat taatttcaaa gcactttcca
    89521 tagatttttc tctaagctca tatgctttct ttacgtcatc tctagcatta ctcaatgttt
    89581 ctgtatactt ctccttagaa agttctggaa tctgcatatt ttcatattct tttacaactt
    89641 ctttacactt gtttctggca tttgtaacat ctttttttat actagataat ttagttatat
    89701 tttttgctat atccttagtg taaggtatgc attctctcat tggaactaaa gctgctcttt
    89761 ctatattata aatttctttc ttaaaaattc ctatactttc catatctatt ttttttatat
    89821 cttcactatt tttttcttta cttgtatatt tattattttc ttttgtatta tcttcttgtt
    89881 tttctgattt attattcact gaaacattac tatcagaatt attcttttct tttatatcat
    89941 tacttccttc ttcattactt tctttatttt gtatatttct atcttgtttg ttgtttaaat
    90001 ttttattatt tgatatttct tcattctttt tattatcctg gtttaaatca gtactttctt
    90061 tttccttaaa atttgataca tacttttcat catatgtctc atcagaaata taattgtgat
    90121 aatacataga ctcttttatt ttattaagtc cactcatata aatattactt atcattattg
    90181 ttgtagctaa taccacataa atactactgt agatacaaga cctcttaaaa ttcttgtaat
    90241 ttctgaatat cactactaaa ggaataagat ataaaaatat aaaaactaat atccacctca
    90301 taagtcgtgt ctcctttctc aaaaccgaaa tccctcaaat atttattttt aatcatgtat
    90361 cttatagtat ttaccaattt atgtttttta atcgtgaact tttattaaat taaattctgt
    90421 atagtcacaa gatgctaatg tatattctac tccatttcga atccccttca atcccatttt
    90481 aaaagattct ttaccatgca agtgaccata aatcaccttt tcaacattat attcttcaaa
    90541 taactttgta aataaagatt cttccaattt atcattcgta ggaggataat gagtaatcac
    90601 aattattttt gagtgaccac ttttacgagc agattctaat gatagtctaa gtctatgttc
    90661 ttctctttta taaacttttt catcagtctc atcaaattta acatcattag gacatatcca
    90721 gcccctacct ccacaaattg cataatcttt atattcataa aaatttgtct gaataaaacg
    90781 catgtcttca tatagcttat ttaaacttgt aacggttgtc caccagtaat catgatttcc
    90841 ctttataagt attttctgac ctggaagttt gcttattata tctaaatctt ttttagcttc
    90901 ggataaatta attccccaag atgtatctcc tagtactaag accatatctt cttccttaac
    90961 aacttctttc caattatcta taattttctt ttcatgacca tcccaattac ttccaaagat
    91021 attcattggc ttattgactg atgttgaaaa atgtaaatca cctatagcat acaaactcat
    91081 aatatcattc ctttcttaat tacactaaat aggctgtctc tttttagaaa ttattttcca
    91141 ttaagaggca gccccattaa tatttagcaa attttctaca agtagttttt actgaactac
    91201 tttatcatct accttagtat ccttatattg ctctaataat atatctattt cttgttttaa
    91261 ttccaaaatt tcagttatat ttttatctgt ttcagttcta tcaagttttc tttggtactg
    91321 catagcttta tgtgtatcac ccaagtcata taactcttgt attctattta gagtatctct
    91381 aatagctata gacttcattt ggtacatagc ctgagctttc attatgtcct ctcttatttc
    91441 actcatttct tggtctaaaa gaaaggcagc atcagatgct cttctaagcc tttcagcaag
    91501 agtctcaggt atgtaatggt catatttata ttttaatgaa tgttctattg tagcccagaa
    91561 attcattgca agagttctta tttgtatttc acatataatt tcctttgaac ccgcaatgga
    91621 gtttataggg tattttatta taacatgata gcttctataa ccactatctt tgtaatttgt
    91681 aatataatct ttttctccta ttatagtcat atcatttctt acttttatca aatcaactat
    91741 agcatatata tcctcaacaa actggcacat tattcttata ccagcaatat catcaatttc
    91801 agtttctata tcttttgcat ttatcctttt taacttagat attatggaag atattttttt
    91861 tgttctacct gtgacaaact ctatgggaga atattcacct tttgctaaat attcttttct
    91921 tatattttta aattttattt ttaattcctc tactgcatgt tcataaggtg ctagtatctc
    91981 attccatttt tcgtattcca tattgctcac cctttatttg ttttttatga ccttctttat
    92041 tttatcataa tttattttgt ttttgtatag taaagcaatt ctccattttc caatatatac
    92101 cctatttctt ctaaatcaac taagtaactt atgacagata ctaacgaaga tttaaaaaaa
    92161 tgatactctt tataattatt gcttaaatta ttgttattta taatgttttt taataaaatt
    92221 tctaaagatt tcggttctac aagcaactct cttatttgat ataaatattt ttttaaagca
    92281 ttcaaatgtt tttctattaa tttataagaa tcttctttcg atataacttg cttgccatgc
    92341 cctaaaacta agtactcaaa atctatattt tttaattttt ctaatgaatt tatttgttct
    92401 tgtatatcat atagaaacaa gaaatcgtat tttgataaaa tttcatctcc tatcaataaa
    92461 tcgccaacaa aaatcacatt atccttcgtc aaaacagcta tactaccagg tgtatgaccc
    92521 tgaaattcaa ttatatcaaa catttcattg tttaattcaa attttccagc ttctataaat
    92581 ttatctattt ttatatcatc caacatttta ttttttaaga tattatccat aaatacattg
    92641 ctctttcccc caacaatata ctttgaaaac aattctggat tttctatata taatttatcg
    92701 tattcagatg acattataca cacatcttta taatattctt taaattgatt acaagctcca
    92761 tagtggtcat catgaccatg agtatttata atatatctaa cctgtatatt attttcatct
    92821 aatactttat ttactctcct aggtcttgaa ccacataacc ctgggtctat cataagtgct
    92881 gtgttatctt caaatacata tattcctgta ttcgtgccac cttttataaa aaaggtattt
    92941 ccttttactt ttgtaagatt caccttcttc acctcatttt gacaatattt atgatacaat
    93001 ttattactta ctaatataaa actatacaag aacaatcctt tttattctat ctatagttct
    93061 ttttcttatt ttgtattctt tagatatcct tattttcaca ttatatgcta aatttctata
    93121 aagtaatgac tctataaaat attcaactat acctctatcc ctaaagtcta tatctatatt
    93181 tccacttgaa taaatatttg agtctaatat cataagctca tcaaaaaagc ttaatctctt
    93241 agatttactt aaataatctt tatttggaat aaatctatca caataatcta tcctgtaatt
    93301 tactacttca tcatttattt caaatccata ttgctttttc attaactctc tatagttatt
    93361 atttttctca ataacattat ctaaattttt attataatcc tcttttttcc aatgtccaaa
    93421 catcctacaa tttaatggtc taacttcata tattaaacat ctattattag tatctttaaa
    93481 tggacatggg ttctttcttg tatactcctc aaaataataa tctaatattt tacttataca
    93541 gctttttttt aaatcaactc tatcttcaag ataacaaaat atattcaaaa actcaattaa
    93601 atttatacct actgactcca tacaacaatt tccacatcca gaacaatttc ctactggcaa
    93661 ggacttatat acatcattta gtttgtcaaa gagcttattt ttaatggaat aatctataca
    93721 atttaaaata tctttatttt ttatactagt cattattatt actccttgtt ataattatta
    93781 agttaataca aacaattatt ataacatatt ttttaaattt aatcgcatat ggaggtattt
    93841 tatgaataga tatacaaaaa taattaatat gatgggaagt tattacacaa aagactttga
    93901 aaaagaaaaa aagaatgtaa taaaagttag agaagttaaa gaagatacag ttagaaaatt
    93961 tttcttacaa ggtgactgtg aagttcttgt agtatttgaa gacactggga aagaaatact
    94021 tattgatgac ttttctcctg aagaagatat caaaaaatat ttaggagcaa aatttataaa
    94081 taaaaaaaga tagttatcaa aaataattct aaaattaaaa tttaataaat gtacagttat
    94141 aattctatat aattatagtt aaaagttatc ttttattgct tttttagact ttaagatagc
    94201 tttttttcta ttttttgtaa aataattcca taattcacat taataattca caaaatgata
    94261 taatataaca aatagataaa tttttaaatt tctaaataca taattaatat tttgcgaggt
    94321 gattttatgc aaatttattt tagagttaag gctgttggca aacgcaaacc tatgctagaa
    94381 cttacccctt ttgatgtatc tgacaacatc aattgcctaa aagaagctat ctctgaaatt
    94441 gtatctaaaa atgttcttga atataatgag aaaatcccag aaaaatcaat aataaacttc
    94501 ttaactaatg aagaaattga atctcaagct gatattggaa aagttggatt tggctctatt
    94561 tacaatgaga ataaacaatc tgtagaaaag gcaatagagg tagcgttaca ggcatttgaa
    94621 gatggaatct acaaagtgct tataaatgaa gatgttattg aaaaactcga ttcctctata
    94681 aatctgaaaa gtggagatat atttactttt ataagactta ccttgcttgc tggaagaatg
    94741 ttttaaaata aataatttgg aggtacataa atgttagaac gtactagagt agaaaaaaat
    94801 cctaaaataa ttgaaaattt taaaaataat tttactaaat cttcttcaaa acagtactac
    94861 gacttagcaa agtctctttg ggactgcata gaaaatagtt catactatta tagagaacct
    94921 gaagacaaat tcttaaatat gataaagaaa tactacaatt gccactacta cgaaattaaa
    94981 aatatggacg agctcctttc tggaccttta aaaaatgcat tagaattaat atttacttct
    95041 gaacaagtag aagaactttg ccaattaatt aaaagaaaga tggattatac atattcagga
    95101 ggatattatc gtaaagggta tcgctcaaat aaacttgtgg attattttag aggtattata
    95161 aggtttattt caaactatgt tgatttaatt tattatgatt tttcagttat agattatctt
    95221 actcttccaa ataaggtctt gtactatgac tctataatga gtgataaaat agcactagaa
    95281 atagacaaag gaaatcaaaa agtaataagt gctttagaag aagtaatatt tggagaaaat
    95341 caaactgctc tacttacaag acaaatgata attggtatca tgaagagtca tagtgataaa
    95401 tgctatgaaa tgctttctaa acttcttttg gcagccaaac aacaagaagg acttagacag
    95461 caaattgtag agagtttaga tgagggtaca atttctgcat caatatacat gttaaaaact
    95521 attttggaca acaatttaga gcgatttagt tctgttataa gagccttgga tacatggaca
    95581 ggacttggtt tttcagacca aaaacctgga ataatacgta aatgtttaga actttcatat
    95641 aaatcattga ctgatgaaaa gttccgtata gaatcaatta atagcaatga taatcttgaa
    95701 atttattttg ccttatgggc tactgcaact tacaacatat atgactctta ctctcttatt
    95761 gaaaacttac tttcttgtca ggaaaaatat aaaaaacttg tagctcttta ctttttatcg
    95821 catacagaaa gtacatattt taaacattct atagcatcta aaaacattaa gggtgatgat
    95881 ttagagatac tagcatgggt aattacaaat ttctatgtag aaggttctgt tggctactac
    95941 tatagttggc aaaacagaga aactaatttt gacttgtcaa acactcctat tgacaaagac
    96001 tttgatgcta gaaaagaaca atttgaaagt ttaaaacata ctttagaaat tttaaattca
    96061 aagacaaaat cattttcagg aagtgtattt ccatggactt ggattgaaat ttcttctcat
    96121 gaaatactta aatgtatgat gactttaaca gcatacgata tgaatgctca atttatagat
    96181 gtgcttatgg aaaattgtca tcttatgagt tcagatttaa gagcttcact tatagtcaat
    96241 tttgtaaatg aaccaaagac agatagacaa cgtgaatttt tattggaatg tttaagtgat
    96301 aagagtgttt ccaatagaga aacggtattg agtctactta gaaagcttga gctaacagat
    96361 gtagaattag ataagataac caatctattg tctttaaaga caagctctat tagacaaaca
    96421 gtaataaaaa ttttacttga acaagatgat tcaaatttgg aaaatattgc ttcttcactg
    96481 ataaaatctt caaattctca aaaatgcctt ggaggtcttg aaattgtaaa cttattaaaa
    96541 gacaatactg ctagacaaga actatataat aagcttgttt tacttataga agatattgat
    96601 aaatctaaaa agaatacatc tcaagttcaa atactaattg ataatttgtt aggtaaagca
    96661 aaaaatgatt actgcaaaga aaatggtttt ggaatatata accctgaaaa caaagttcaa
    96721 attccagaac aatttgattt taaagatgat tctaatagct catcaaagct taataaaatt
    96781 atctcaaata taagtttatc tactcgtgag gattctgttt ctgtagcaac aaaaaaagaa
    96841 gcaaaaaaaa ttctcgatac ggatataaat aaaataataa aagtttatga aaaatttgat
    96901 gagcttatta ctgaaaatgc agattatgaa tatgaagttg aaagatggtc aggtaatgta
    96961 gacaaagtac ttttaggtta ttctacttat aacttgactc ctattaaata taaagtttct
    97021 aatgatactc ttgataatta tccattagca gagctttgga gagaaactag taaaaagctt
    97081 gacttagatt acaaattaat acttgatatt ttattttata gtataagtac atgtggatat
    97141 aatgaaacag aaaaaagttg gttttcatct atatattcaa atgtccttga ctctaaaaaa
    97201 caaaataaaa tatatacaaa acttgaaaaa cttaaattta atggacttac aagaaaactt
    97261 ttaagagttt tactaaatga gtttgaccat aaagaaatat ttaactattg tttagaaata
    97321 tactataaac ttagaaactt attgactata gaacaatgta aaaaacaaag agttgaattt
    97381 actaaaaact attacagaca aaatgaatac tgccctgctt taaatgcccc tattttaaac
    97441 tattggcttg ataaagcaca ttcgtttatt tatgatgata tttcttttac taagtttttc
    97501 tacactacgt tttcaaatta tcagttgcta gaatataagt ttcctttcta tactagcata
    97561 aatgtgtttg ctcgtgcaca tgaattagga ttaatgactg aagagcaagt taatagagaa
    97621 atgataagtg gatacaacgc atcaaatata ataagaacat tgacaaatcc tagatgggct
    97681 ggcgacacat tagaaaagta cccttggctt aaagataatt taaaaactgt tacaaaccga
    97741 attatagaaa ttgaatcacg tagaggtgat atgccaacag aggtgtctca tctagctaat
    97801 aatatacaat actttgaagg tataaattat tttgtaaata ttttggtcgc tcttggtaaa
    97861 gaaacgttcc agagaggata ttcatatggt agcaattatt caaaaaaaga tgttttaagt
    97921 tctctactta aaaattgcta tcctactaaa gaagatgact caaaaaaatt aaaaagttta
    97981 cttaaaaata ccgacattac tgagttaaga ttgatagaat ctgctatgta tgcccctcaa
    98041 tgggtaaaca taattgaaaa atatttaaac tggaagggtc tgaaaagtac aatttggtac
    98101 ttccatgcac atataaatga aggcttctct gcacaaaaag aatcagaggt tgctctattc
    98161 tcccctattt caccacgtag tttcattgat ggtgcatttg atgtagattg gtttttagat
    98221 tcatataaaa ctattgggga agaaagattc aatatacttt acaagtcagc taaatatata
    98281 actagtggtg gtaactctca tagacgtgca caactctatg ctgatgctac acttggtaag
    98341 cttgataaag acatgttgat gaaagaaatt gaaacaaata gaaatcaaga taaattgaga
    98401 agtttctctt tacttcctat gaaaaaagga gacctaaaag aagcaacttt ccgttatgaa
    98461 tttattcaaa agtttgctaa agaaagcaag caatttggtg cacaacgtcg tgaaagtgaa
    98521 tcaaaagctt gtactatagc gctagaaaat ctagctagaa gtgctggatt tggagatgta
    98581 aatcgtatga tgtgggctct tgagactgaa aaactaaatg aagttgctca tctatttaaa
    98641 ccaaaagata ttgatggtac ttcaatttgg atagatgttg atgaaaacgg aaaagcatct
    98701 actaaagttc aaaaaggcaa caagtcttta aagagtatac caaaagctat tgctaaacat
    98761 ccatatgtac ttgaacttaa atctgtccaa aaagatttaa agagtcagta ttctcgtgca
    98821 aaacagagtt tagaacaagc tatgaaaaat gaaatagtat ttacagttaa agaaattgcc
    98881 aatatctata aaaatccagt tatctgccct ttgattaaaa atctagtatg ggtatgtgat
    98941 gataatattg gatatgttta taatgataag tctaagttct ttatttgcaa tatagaaggt
    99001 gaaacttata agttgacggc aaaaaataaa ttaaaacttg cacatccagt tcatttgttt
    99061 gaatctggta agtggagtga gttccaacat gatttattta gtaagcaaat tgttcaacca
    99121 tttaagcaag tattccgtga gtattataga ataaacagtg atgaattatc tgaaaaaact
    99181 atatctcgca gatatgctgg tcaccaaatt cagccaaaga aaactgtagc acttcttaga
    99241 aatcagcttt ggactgtcga ttatgaagag ggattacaga aagtatttta taaagaaaat
    99301 atagtggcaa agatgtttgc acttgcagat tggttttcac cagcagatat agagcctcct
    99361 actattgaaa cagtagaatt ttttgataga aaaacttata aaagtttaga attagcttct
    99421 atacctccaa ttctattctc agaagttatg cgtgatatag accttgttgt aagtgtcgct
    99481 catgctggtg gtgttgaccc tgaaactagc cattctactg tagagatgcg tatagcaatt
    99541 gctaaagaac ttttattatt attaaaaatt aacaatgtca attttgaagg ctctcatgct
    99601 cttatagcag gtaatttagg tgagtattct gtgcatatgg gttctggtat tgtacataaa
    99661 aaagggatgg gtgctttgaa tatacttcct atacattctc aaagtagagg taagatattc
    99721 cttccattcg ctgatgaaga ccctaaaact gctgagatta tgtctaagat actattactt
    99781 gctgaagata gtaagattaa agaccctagt atcttaagta atttataagt ataaaaacta
    99841 tccctaaaat atattggact ttcttaaaaa aaattagaaa gtccaatata tactatactg
    99901 taatttatat agattaaatc ataattacaa ataattttta tataaacttc tcttatacat
    99961 tatctttatg gtacttatta tatcacacaa aaagtatttt tcttctatct tcactagaat
   100021 cttttaaccc tataaaatct atataaaaaa tctttttcta gagatttgtt taatatggca
   100081 ttttcttgaa aatttataaa ccttatctct aatgaagatt tatttatagg tataacctta
   100141 tgtataaatc ttagatttac tatgtattgt ctatgggtca taaagaaatt aggaggtagg
   100201 cgttttttta aatcatcaaa gttctcataa aactttatta tatcttcatc tttagtgtgt
   100261 agattaattg ctcttgaatt tttctcaaac ataactatat catcaaaatt aatcatatgt
   100321 atctgcttcc ttattttata tacaaaaagg gtgtcttcta taaaattatt attagcaatc
   100381 ttatgggagt taatatggtc tattgctatg ttaattgaat caagtatttt ttctttttta
   100441 aatggtttaa ctacaaaatc tataggatgc actttaaagc tttcaagact ataatcagcg
   100501 aaacccgtca caaatactat atgtatatcc ttatctatag aaagaatttc ttcagcagaa
   100561 tcaatcccat ttttatatgg catatcaatg tcaataatca ataaatctat tttctcattt
   100621 tttataaatt caattgcctc tataccatcc ttaacttttt taacataatc tacatatcca
   100681 gactctttag ctatatttgc tatatcatct cttacaatct tatcatcatc acaaatcaaa
   100741 acttttatca tagacttttc tcctcctaac taataatatt ttgggattaa gattacaaat
   100801 tcagttaaaa aatcatcact atttacaagt atactataat catacttatc taatatattt
   100861 ttaactaaat gtagcccata tcccctatct tgtccttctt tagtactaaa tccattccaa
   100921 aatatacttt caacattatg tattttagga ccattatttt ttatagctat aatatactga
   100981 aattcatctt catatgcatg tactcttata tacttctttt ctttttttat agtagacaaa
   101041 gactctattg cattatctat tatgtttaat agtactgaac tcatatcatt aggttcaatc
   101101 tctaaattat ccataaaatc ttgaatgtag acatcaaaag atatatcctt ttcaagacat
   101161 tcctcgtatt ttaatgaagc tatagcatct aaataagata cttttccata ccttgaattt
   101221 tttgatttaa aactatttga tatattcatt atatattctt tggcatcttc atctagccca
   101281 gtatttaata gagaatacac cacttgcaaa tgtttcaaat agtcatgttt ttgacttctt
   101341 aatttgataa ttatattatc cttatgattt attttactat ctagtttttg tagtttatat
   101401 tcctgttcat tattattatt tatcaatctt ataactttaa agcctgtata aaaacttaaa
   101461 ataattaaaa ccaaaaaaag tataatattt aatactcctt caagtaaaaa actatatcct
   101521 aaccttaatt gtatatattt agtgccctcc ataaataaaa tcaatgcaaa acacgatata
   101581 aaaaatgtta atatgcctct ttttaatatg tctaattctt tgtaaaattt atacttattc
   101641 attataagat tgctaaatat aaacaaagtt agtattacta taggaaatac aaaattgtta
   101701 gccatgattt ccctcccctc tacaatttat atagggatta tatcatttta aaaaaattat
   101761 gtaaaaagtt aaaatttaca tatagattaa ttaaacttgt aaaaatacag atgaatttgt
   101821 acaattaact acttaaaact tgaaaatact tactttgcta tatattttag ataaatatat
   101881 aattgattta gttaagaaag gaagtggtaa atatgaaaga taatttgaaa atagtactaa
   101941 ggtatataaa aagttataaa gctaggtctt tagcaattgt tgtgagtata attcttgcta
   102001 catcactcgt tgttggtatt ggtaccctct caagaagtgc tcagcaagca gatgtagata
   102061 gattgaaaag agagcttgga actgaccatg tatactttaa aaatataaag aaaaatcaat
   102121 taaagtccat aaaatctagc aaagatatta aaaatctggg tataacatct tactatgcgt
   102181 ctacagatgt taatgaaaaa ttacctataa acatactata tgcaaataaa aattatttga
   102241 ctagtcattc taaacttata aaaggtcgat ttccaaaagc tagcaatgag gtggtagtcg
   102301 agaaatggat tttaaatagt atgggcttaa aaccagagat aaatcaaaac cttactttta
   102361 aattatatca aaaagaaaat ccagaaactt ttaaagttgt tggaatcctt gaagatagat
   102421 ttatagagaa aaaaaaggga caatgtgaaa ttttttctaa tctcaatgaa tcagaactga
   102481 atgattttac aacttatatt gaatttaatg aaggcagtga tataaataca aacatagaca
   102541 atataataaa aaatgctatg ttagatgaga aaagtatagg aagaaactca atgcttatag
   102601 aatctactat gaaaaacggt actttagata attcaagtaa atacgttgca attgctatga
   102661 gtctatttgc tggtattgta atatatagta tctatgttat atcaatatac caaagagtac
   102721 aggaatatgg cgtcttaaga gctattggtt ccaccaactt taggattttc aaacttatgc
   102781 tttatgaact tttcatactt gctctaatag caatgcctat aggtatatgt ataggtatgg
   102841 gaggtgcaca aatatttaat aggtctgtag gaaatattca atttgaagga aatataaatg
   102901 ttacaccttt tgttattcca gataaaataa ttctcttatc aattgcatgt acaatactaa
   102961 taatactaat tataagtttc tttacatact taaaaataag aagaatttct cctattgatg
   103021 ctatcagaaa aacttttgga gctgataaaa atgtaaccaa agttaattat ttaatatcaa
   103081 aattaacttt aaatatgtca gtaacaaaat ctatatctgc gaaaaacatc tttagaaata
   103141 aaaaggggtt cattataatt gtattatcta tgagtatagg aggtataatc gtcataaaag
   103201 acaattataa atattctttt ttagatgtgc aaaacaaatc tactcaagaa caaacatata
   103261 tgaatgcaga ttttattcta tcaaatgttt atctcaatga aattggtaac aatacttctt
   103321 ttaaagatat aaaagggttt aatgataatc agatagataa aataaaaaat atagatggaa
   103381 ttgacaaagt caaaactgct agtatcttaa acacaagaat agaggtaaat aaaataaata
   103441 gattagatta ctacgaagct ataaattcaa ctccttatta taagctaaat cctctgttca
   103501 taaaaaataa gactactggc aaatatacac taaagcaaaa gctaaaaggt tataatgatg
   103561 agatgataaa gtcattagaa aaatacttag taagtggaaa tataaacttg aaaaaaatga
   103621 aaaaagaaaa tttagctatt gtatatgtac cagaaatttc taaaacacag aaatacacaa
   103681 agacttttac tcctggtgaa ggaacaccag ctgtagatat aaaagtaggt gatactataa
   103741 aagtcaaata tccaaagggt gggatggata cagggcttta tgaaagtcta aaagataatt
   103801 atgaatactt agaatatgaa tttaaagttg gagctattat aagttatcct tttgcagata
   103861 atggtatgta ctctggagat gatggtgtag atgtaataac gagtagcgaa tacctaaaaa
   103921 aattaactgg tgtagataag tataacttag tttatgcaga ccttaatgaa aatgcaaaca
   103981 agaaaaaaat aaataacctt ttaggtaaaa ttggaagtga agttcctgga actacaacag
   104041 tagatatgat ggtagaaaaa gaaaattctg ataagatgac atctagaact atgatttata
   104101 gttatggtat agtagcaata atgttcataa tcagtgtact taacataata aacaacataa
   104161 gttataactt aacttcaaga actagtgaat ttggaatgtt aagagctatt ggtatctctg
   104221 agagaggctt taaaaatatg atactttatg aaggaatatt atatggtgta ctctcaagta
   104281 taattactat cgtgtcagga attataatac aatttaaaat gtattatatg cagggctttg
   104341 tatcatatgg attgggattt tcaatagatt acaaaatata tatcctagtt attttagcaa
   104401 atataattgt tggtattcta gctacatata ttccatcaag aaagataaat aaaattagta
   104461 tagttgaagc tataaacatt acagaatagg agggataatt atgcctatat tggaaactat
   104521 taatttaggt aagatttatg ggaaaaagga aacatctgta catgcactaa agaatgcaaa
   104581 tttaaaaata aataaaggcg aatttgttgc tataattgga ccaagtggaa gtgggaaaag
   104641 tacatttcta catttagtag gtggtcttga aagaccaagt aatggtacta taaaggtaga
   104701 tggtaaagat atatgttgtc tttcagataa agaattagca agatatagaa gacaaaaggt
   104761 aggatttgtc tttcaacagt ataacttaat tcctgtatta aatgtaaagg aaaatataga
   104821 attaccacta aagttagaca ataaaaaaat agataaagaa tatattgatg accttataaa
   104881 tttattgggt cttaatgaaa ggaaaaatca tcttcccaac caattatctg gtggtcaaca
   104941 gcaaagagtt gctattgcac gtgctttatc tgcaaaacca agtataatcc tagcagatga
   105001 accaacagga aatttggaca gtaaaactac agaagaagtc atggatttac taaaaagttc
   105061 tataaaaaaa tataaccaaa cccttataat aataacacat aatgaaaata ttgctagaaa
   105121 agcagataga attatatcta taatagatgg agagcttaaa ttaacactct aaaactattt
   105181 atagaaaaga ggatttaaat gttattgatt ttaggtaatt taaatttaaa cttggatttt
   105241 gactacagaa taataagaga agaaaatgat gatgtagata tatttataga tattaattat
   105301 cgtagcttag atatagatac tgatggttct aacttattta attctagaat acaatttcca
   105361 tttgtaagag cattgattct aaggctaaat aagaacaatc aatgtatgac aattcatttg
   105421 ttaagagata tagatttatt ctctgctttt gccaactttg aagtggatta tactgactct
   105481 ataataaata taaaaaatca aaatgagaaa gtaattttaa ataaatctat caaaaaatag
   105541 taagggggcc ttaataggcc ccaatttttt tcttttctaa acttattata tcatgataaa
   105601 taaattagtc aatagaattt tctgaatatt tttataattt tttcataaag ttttttatat
   105661 attatgcttt aaaattatat gtaataaaaa aattttccga ctaattttaa agttaattga
   105721 ttaaatacac atattcgaaa ttaccattaa attactgact ttttatcatt tccatttaga
   105781 atttaagtta taatctatta tttatagtta cttctacgtg tctctaataa aactctattt
   105841 atattcaaat ctaataattt atatacaaac ccaatagaac ctatgttgca caatagatat
   105901 tatttaccat aataaacttt tagatatatc tcttttaatt cactcatcaa tgggtatcta
   105961 ggattagcac ctgtacattg gtcatcaaaa gcttgttcaa ccatagcatc caatctttct
   106021 aagaatttag attcttctac tccagcctct tttatagtct taggaagacc tacttttgcc
   106081 tttagttcat ctattgcttt tataagatta tctacttttt cttggtctgt acttccttta
   106141 atacctgcaa aagaagcaaa ttcagcatat ctttgtatgc aatcaggata tctgtattgt
   106201 gagaatgcac ccattttatt tggagcttct gcacaattga acttgattac ttcatttatt
   106261 aataatgcat ttgcaacacc gtgttgaaca tggtggaatg cacctaattt atgtgctaaa
   106321 gagtgacata ttcctaagaa ggcatttgca aaagacattc ctgccatagt agatgccatt
   106381 gccatttttt ctcttgcttc tttatcattc tttccatttt tatatgcacg aggtaaatat
   106441 tcaaatatta ttttacctgc ttgtagtgct agaccgtcag ctggttcagt tcttaacata
   106501 gatacatatg cttctaatgc atgtgttaaa gcatcaacac ctgatgctgc tgttaatctt
   106561 ggtggcatct ccatcatcat atcagcatca attatagcca tgtttggcat taattcataa
   106621 tctgctaatg ggtactttac acctgaatct tggtcagtta taactgcaaa tggagttact
   106681 tctgaaccag ttcctgctga agttgggata gcagcaaaat acgctttttc acccatctta
   106741 ggaaatacat atactctttt tcttatatcc ataaatctca tagctaagtc ttggaaatct
   106801 acttctggat gctcatacat tacccacatt atcttaccag catccattgc acttcctcca
   106861 cctacagcta ttattaaatc tggttggaaa tcagccatag ctttagctcc ttctcttgca
   106921 caagctaatg ttgggtctgg agctacatca aagaatgtag tatgcttaat tcccatctca
   106981 tctaataaat cagttaattt cttagtatat ccattattat ataggaaaga atctgttact
   107041 ataaatgctt tctttttatc cataacatcc ttaaattctc ttgctgctac acctaaacat
   107101 ccttttttga aataaacctt ttctggtgct ctgaaccaaa gcatattctc tctcctttca
   107161 gctactgtct tgatattaag caaatgtttt actccaacgt tttcagatac tgagtttcca
   107221 ccccaagaac cacaaccaag agtaagagac ggtgccaatt taaagttata taaatcacct
   107281 ataccacctt gtgatgatgg agtattaact aatactctac aagtcttcat agcatttaca
   107341 aacttttcta ctctctctgg atgatttata gagtctgcat ataatgaaga tgtatgacca
   107401 tagcctccat ctgcaactaa tttttctgct ttagcaactg catcttcaaa acttttagac
   107461 ttgtacattg caagtacagg agaaagtttt tcatgtgcaa aaggttcatt taattcaaca
   107521 gattctactt caccaattat tattctagct gtttttggaa cttctacatc cgccattttg
   107581 gctattacat gtgctggttg tccaactatt ctggcattta atgaaccatc aattattact
   107641 acttttccta ctttttcagt ttcttcttta tttaggaaat gtgctccacg atatttaaat
   107701 tcttttttaa cttcttcata tattttttct ggtactatta cagcttgctc ggaagcacat
   107761 atcataccat tatcgaatga ttttgatact aagattgaac ttacagccat ttttatatct
   107821 gcactctcat ctattattgc aggtacattt ccaggcccaa ctccgacagc tggtttacct
   107881 gaagagtatg cagatttaac cattccaggt ccaccagtag ctaatataag gtctgcctct
   107941 gccatgacaa cattagttaa ttcaatcgaa ggaacatcta cccaacctat aagtcctttt
   108001 ggtgctcctg ccttaactgc tgcatcatgt acaactctag ctgcttctat agtacagttt
   108061 ttagctcttg gatgaggaga gaaaattata ccatttctag tttttagtgc tattagggat
   108121 ttgaatattg cagttgatgt aggattagtt gttggtataa ctgctgataa aacacctact
   108181 ggctcagcaa ttcttgtaaa accaaatgct tcatcttttt ctatgacacc acaagtttta
   108241 gtatctttat aagcattata gatatattct gaggcaaaat ggttttttat aaccttatct
   108301 tcaacaatac ccataccagt ctcttccact gccatttttg ctagaggtat tctttgttga
   108361 ttagctgcag ttgaagcagc taagaaaatc ttatctacct gttcttgcgt aaatgttgca
   108421 aattcttttt gtgccaatct aatttcttct aatctcattc ttaatgtttc aacactgttg
   108481 acaatttcag gactacatac ttcaacattt gatttttcta ctaccttttc ttttttctcc
   108541 atactaaaaa cctccctaaa ataattatgc atctctaatt tttattaatc ttaaatgcat
   108601 catctatatt tttaacttat acttaaaata attttataga tttcatctct ataccttaga
   108661 ttttatttat tttactctct taggtcaaga agtttttttc tgaatatttt gtcaatttat
   108721 tttttaacaa atatattatt ttttttactt ttactaaaat tttttatcta aatgagatat
   108781 atttcatttg aataatttac ttcgactaaa taaaatacta aaatgataat ttatatcttt
   108841 catttttttt acttattaaa ttttatatgt tatttgcatg ttatttgtat aagtagtaaa
   108901 taaaattttt gtcgtatttt tataaaataa cacttatttt tgacttgtat gcaatttttc
   108961 tttttataac aact
//
LOCUS       DAEPKC010000003       106218 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.003, whole genome shotgun sequence.
ACCESSION   DAEPKC010000003 DAEPKC010000000
VERSION     DAEPKC010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 106218)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 106218)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..106218
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.003"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..902
                     /locus_tag="KR294_000245"
     CDS             <1..902
                     /locus_tag="KR294_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HBH0238363.1"
                     /translation="GFNNVSTISNNIILYTWIITVVVYLIYTIFKYIKLKNLINDLSY
                     DVDDREIVNLYKNILEEFNITKDIKLKYSYEVETPAFFNSCVLLPPHEYKLKELDWIF
                     RHELMHFKSRDLYLKYVILFLKTVYWFNPFIYIMDKHIDLDCELYCDERVLKNRNSEE
                     KKDYALTILNAMRKGSNTSNKFIAGLHKQSDIKKRVMNMFNEKYKNGILMALTLCLLS
                     SITFLKVNSTSIVNLNVLPKGFEDLRTVSSIRFSVIGFTYADAPKNMREEYKINCESL
                     GLIPKDSDKIEVGIEYYDSLLND"
     gene            1818..2840
                     /locus_tag="KR294_000246"
     CDS             1818..2840
                     /locus_tag="KR294_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBH0238364.1"
                     /translation="MKKKILIPVFASVMALSVSSIVNADEVNDSSQNKDDKTNTELNL
                     GEYKEVKYKVAKIKDGVAIKIREEGQVQNIAYSGDEFTVLGTQGEWVKVKVEDGEGWL
                     ATRYVDISEGVGYTNADKVNLRKDKSESSEVIEELEKGSSLLVLEDNGDWLKVKDGET
                     EGYVKSSYISDKAPVIEEPQVNPSIDQNVDSTNNNQQNNANTNQQNNNSNVPTANSNA
                     VQAVLNLAYSKQGCPYVWGAEGPNTFDCSGFTQYVYRNAVGKNIPRTSKAQSKYGQTV
                     SKANLQPGDLVFFTTNGSGSVSHVGIYVGGGNMIHSPSTGKTVSVTSINSSYYTARFV
                     TAKRIL"
     gene            3137..4057
                     /gene="pyrB"
                     /locus_tag="KR294_000247"
     CDS             3137..4057
                     /gene="pyrB"
                     /locus_tag="KR294_000247"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase"
                     /protein_id="HBH0238365.1"
                     /translation="MLKSRNLIQPEDFSIEEIDEILELAQKIIDNPSKYSRICEGKLL
                     ATLFYEPSTRTRLSFESAMNRLGGRVVGFSEPNSSSASKGETLGDTMRIVSGYVDIIA
                     MRHPQSGAASEAARYTEVPFINAGDGKNQHPTQTLTDLLTIKSLKGTLESHTIGLCGD
                     LKYGRTVHSLVKAMARYKNTKFVFIAPEELKMPDYIKEAIKGHAYYETNNLDDVIGSL
                     DVLYMTRVQQERFEDKSEYERLKNYYILNKAKLEKASKDMLVMHPLPRVNEIDIDVDS
                     DDRAVYFKQAKYGMYVRMALIIKLLGINED"
     gene            4096..4788
                     /locus_tag="KR294_000248"
     CDS             4096..4788
                     /locus_tag="KR294_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HBH0238366.1"
                     /translation="MYKILENIYIGEDMYRMKVKGNFEGKMGQFYMLRAWDTYPVLSR
                     PISIHDIDEEGITFLYKVVGEGTQILSNLKVNDTIKLEGPYGNGYAKVDGKVALVGGG
                     IGVAPLYLVAKNIKNCDAYLGFREDVILEDEYKQVCNKVYTTVGNTFVTDIIDVEKYD
                     YILTCGPTPMMEKLVKMVEGTKTRIMVSLENHMACGVGACLVCTCKTNGGNKKTCKDG
                     PVFWGEDVIFNG"
     gene            4781..5683
                     /locus_tag="KR294_000249"
     CDS             4781..5683
                     /locus_tag="KR294_000249"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HBH0238367.1"
                     /translation="MGNLSVKFGSVEFKNPVIMASGTFGFGKEYNEIYDIQKLGGISS
                     KGLTLNKKPGNNGMRVHETPSGMMNSVGLENPGVQGFIDYELPFFSKLDLVRIANVGG
                     GTLEDYLLGVQMLNDKPIDIIELNISCPNVKAGGMAFGIKNEVAREVVREVRNITKLP
                     LVIKLSPNAEDIVGMAKVCEEEGADGVSLVNTFKAMAIDIKNRRPVFENVYAGLSGPA
                     IKPIALRMVHEVCKNVNIPVMGMGGITKATDAIEFIMAGATCIQVGTANFMNPRIGIE
                     IIDGINEFMDREGIKSLDEIRGII"
     gene            5768..6352
                     /locus_tag="KR294_000250"
     CDS             5768..6352
                     /locus_tag="KR294_000250"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HBH0238368.1"
                     /translation="MSKVDVVDILKKSDALLEGHFLLSSGKHSNRYVQCAKVLRFPEY
                     AAEVLSTVVEQIKDLDIDLVVGPAMGGVIVSYELGRQLGKEAVFTERKDNTMELRRGF
                     EVKKGAKIIIAEDVVTTGKSTMETKRVLEALGGEVVGVACIADRTNHDIGMPIYSAIK
                     LDIQVYESDECPLCKEGKLPVVKPGSREFKELGM"
     gene            6567..7493
                     /locus_tag="KR294_000251"
     CDS             6567..7493
                     /locus_tag="KR294_000251"
                     /EC_number="1.1.1.169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HBH0238369.1"
                     /translation="MKNQLNENHKKVVFFGVGAVGATFAEQFFNSKYDFKILCDNERK
                     KRYLEEGFIINGKRYDFDYVTKDEYKQEADFIIIGLKYNNLKENIKELDGLVGKNTVI
                     MSLLNGVDSEEIIGERFGIEKMVYSYVTNIDAKKINNNIIHTTNGIIVFGNKDNSEDR
                     KTNIITEVFDDVNIEYTLSKDIQRDMWWKYMVNIGVNQTSAILGAPYGVFQSSEHLRE
                     LAKSAMREVVAIAQAKDISLTEDDVEHSLHRILEHSKEGRTSMLQDVEAHRLTEVDMF
                     SKNICKLGKKYNIPTPINQTFFYMIKVIESRF"
     gene            complement(7545..8435)
                     /locus_tag="KR294_000252"
     CDS             complement(7545..8435)
                     /locus_tag="KR294_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBH0238370.1"
                     /translation="MFEELKTFVAVVEYKNFTKAGEYLNLSQPSVSKHIKNLENYFKV
                     VLINRSIKQKTIFITESGQILYKRAKEILNLLNITYHDVSQVSDAITGHLKIGASLTI
                     GEYILPNFLALFSKKYPDIDVEVFIKNTSIVSSHVKDYILDIGLIEGTCSSPSFIQEY
                     FFEDKMVLALPYKSHLLKDFSFDKLQNQKWIVREDGSGTRDYLDMFLSVKEIIPKSMM
                     VFGSNYAVKESVRNNLGITIVSNLVTSLPVLNNELSVIELGSSYNRHFSYIFPKDITL
                     SKAATIFIEELKIFSNLNSI"
     gene            8623..9654
                     /locus_tag="KR294_000253"
     CDS             8623..9654
                     /locus_tag="KR294_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HBH0238371.1"
                     /translation="MLKKKSSLTLKTIREILPGLFVSVLVGYISIFISILIPKVGAAS
                     ISIFLGMFVGNLFLNQKVFQKGYKFSETDLLSYSIVLLGATLSVSTLIDLKVSGILFI
                     ILQMTITIIAALYIGKKLGFEENFRFLMASGNAVCGSSAIGATVPVVNATDKEKGIAV
                     TIVNVTGIFLMFLLPIISQFLYSHELVKTSAMIGGTLQSIGQVVASGAIVGENVKDLA
                     TIFKIVRVIFLVVVVLVFGHMKNQSNREILEEEKDEIKKKKVTIPWYVIGFFITCALF
                     SMNIIPQEVSVLCKEISNKLEIIALAAIGLKVNVKDLVKQGKEVSLYGLFVGIVQVVS
                     AVVLIKIFI"
     gene            9948..10823
                     /locus_tag="KR294_000254"
     CDS             9948..10823
                     /locus_tag="KR294_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA glycosylase"
                     /protein_id="HBH0238372.1"
                     /translation="MNVYEKGNGVILEGVTDFDPVHIFECGQCFRWHKQEDGSYTGVA
                     KGRILNVKKENDKIYLNNTNLKEFNSIWYNYFDLGTDYTEIKNKLKNMDEYLNKATEF
                     GWGIRILRQDGWEMLISFIISSNNRIPMIQRAIENLSRKFGKYIGEYEGNEYYAFPTP
                     EELNKASQEEIRACQTGFRDKYIKSTTQAVIENNDEVSEYTNLSTEDCRKELLKFNGV
                     GPKVCDCIALFGMQKYDSFPVDVWVKRVMQEFYIDEDMSLPKMRTYGIDKFKEMSGFA
                     QQYLFYYARELGIGK"
     gene            10841..12331
                     /gene="cls"
                     /locus_tag="KR294_000255"
     CDS             10841..12331
                     /gene="cls"
                     /locus_tag="KR294_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HBH0238373.1"
                     /translation="MGVIGTIFLFYLIISYLAGAIISVIILLENRDPAKTMSWLLMFI
                     IFPGVGLMIYAISGRNIRKRKLFKTQKLANNIKEKKLFDTLEKITEIVELEKESIKQN
                     KLLRDEEDGSYRKRVINMLLKTGMFPFTKNNKVDVFVDGNEKFKRLIEDIREAKDHIH
                     LEYFIIKDSEIGRVLKEELIKKAKEGIKIRILYDDVGCWRFWFNRKFFREMREVGIEI
                     AAFLPTKFPIIGGKLNYRNHRKIVVIDGIIGYTGGINIGDEYLGKNDKFGYWRDTHIR
                     IKGISVYMLQMTFLIDWYYTTKEVLVTKNYFPSVGNVGESMIQVVASGPDSDWEDIHY
                     AYFSAICQARKNVYIETPYFIPDESLLKAIKSAALSGVDVRIIFPKIADHKIVNIASY
                     SYFEEILRAGGKVYLYNKGFIHSKVVIIDDKIASAGTANMDLRSFMLNFEVNAFIYDE
                     EVIRVMTDDFFEDLSHCEELNLEVFKNRNIIQKIKESVARLFSPIL"
     gene            12524..12808
                     /locus_tag="KR294_000256"
     CDS             12524..12808
                     /locus_tag="KR294_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012062101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HBH0238374.1"
                     /translation="MKIRPLADRVVIKKVEAEEKTASGIVLPGAAKEQPQIAEVVEVG
                     PGGIVEGKEIKMELTVGDKVIFQKYSGTEVKIEGQEYTILRQSDVLAVIE"
     gene            12841..14469
                     /gene="groL"
                     /locus_tag="KR294_000257"
     CDS             12841..14469
                     /gene="groL"
                     /locus_tag="KR294_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729227.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HBH0238375.1"
                     /translation="MAKEIKFSEETRRALEAGVNKLADTVKVTLGPKGRNVILDKKFG
                     SPLITNDGVTIAKEIELEDRFENMGAQLVKEVATKTNDVAGDGTTTATVLAQAIIREG
                     LKNVTAGANPILLRKGIQKAVTVAVEELKNQSRIVETQEAISQVASISAGDEEVGKLI
                     AEAMEIVGKDGVITVEESQTMNTELDAVEGMQFDRGFVSAYMVTDVDKMEAVLNDPYI
                     LITDKKISNIQELLPVLEQIVQQGKKLLIIAEDVEGEALSTLVVNKLRGTFDVVAVKA
                     PGFGDRRKEMLQDIAILTGAQVISEELGYDLKEADLSMLGRASSVKVTKESTTIVDGS
                     GDKKAIEDRVTQIKHQVEQTTSDFDREKLMERLAKLAGGVAVVKVGAATEVELKERKL
                     RIEDALNATRAAVEEGIVAGGGTAFVSVIPAIGTLIESLEGEVKLGAQIVKKALEEPL
                     RQIAINAGLEGAVIVQNVVNSEAETGFDALNEKYVNMIEAGIVDPTKVSRSALQNAAS
                     IASTFLTTEAAVADLPEKEDVGMPGMGGGMPGMM"
     gene            14731..15471
                     /gene="larB"
                     /locus_tag="KR294_000258"
     CDS             14731..15471
                     /gene="larB"
                     /locus_tag="KR294_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel pincer cofactor biosynthesis protein
                     LarB"
                     /protein_id="HBH0238376.1"
                     /translation="MDLRKLLEEVKNENIDIDFALEKLKDLPYEDLGYANIDHHRELR
                     NGYPEVIYCEGKSDEHILGIIDKMNQKSSNILGTRCRKETFLKIKEIYNHAEYEEASK
                     ILKIQNHDIENIGKGKIVIATGGTSDIPVADEAYHTAKFLGNDVDRIYDVGVAGIHRL
                     LNKRHKIDSARVIVAVAGMEGALASVIGGLVDVPVIAVPTSVGYGANFGGLAALLAML
                     NSCASGISVVNIDNGFGAGYLASMINKL"
     gene            15555..16289
                     /gene="larC"
                     /locus_tag="KR294_000259"
     CDS             15555..16289
                     /gene="larC"
                     /locus_tag="KR294_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel pincer cofactor biosynthesis protein
                     LarC"
                     /protein_id="HBH0238377.1"
                     /translation="MSEKILYFDIISGISGDMTLASLLNLGVPKEIFLEEIHKLRMSD
                     EFNINISSKTENGIVGTKVEVITKEKHTHRNLVDIFEVIDKSTLNENVKSKAKKIFMV
                     IGEAEAKVHGTTIDKIHFHEVGAIDSIVDIVGASILVDLLCVDKVCASTVSVGSGFVK
                     CEHGIIPIPAPATIEILKGVPIKLNNVNGECTTPTGAAIIKVLCDEFVDELEFSPKQI
                     GYGIGHKKFEVPNILRTVLGEKKKKN"
     gene            16319..16738
                     /locus_tag="KR294_000260"
     CDS             16319..16738
                     /locus_tag="KR294_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF111 family protein"
                     /protein_id="HBH0238378.1"
                     /translation="MSSEIYSYLYEKILDEKALDIYTESIYMKKNRPATKVSILCNES
                     DLEKFIKILLLETSTFGVRYNAYNREILERKFVKLDTKYGVVTVKLGYYKGKLVKATP
                     EYNECKTIAKNEDIPIKKVFADINFRIKEEFSENLLT"
     regulatory      16798..16899
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            17120..18655
                     /gene="guaA"
                     /locus_tag="KR294_000261"
     CDS             17120..18655
                     /gene="guaA"
                     /locus_tag="KR294_000261"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HBH0238379.1"
                     /translation="MKHELVLVIDFGGQYNQLIARRVRENNVYCEILPCTASIERIKE
                     KNPKGIIFTGGPNSAYLEDSPTISKEIFELGVPILGICYGIQIMSHVLGGVVRKGNKQ
                     EKEYGKTAITYGKSSLFEGITTNSVWMSHTDLIEKVPEGFTIVANTNDCPVAAMENVE
                     RNLYGVQFHPEVEHCLEGDKILTNFLYNICKVKGDWTTDSFIEDKIKELKEKIGDKKA
                     LCALSGGVDSSVAAVLIHKAIGDNLTCIFVDHGLLRKNEGNDVERIFREKFDINLIRV
                     NAEDRFLSKLKGVSEPEAKRKIIGEEFIRVFEEESNKLGKMDFLVQGTIYPDVIESGH
                     GNAATIKSHHNVGGIPEDVDFQEIVEPLRELFKDEVRKIGLELGIEEGLIFRHPFPGP
                     GLGIRVIGDVTKEKCDILREADAVYMDELRKAGLYREIWQAFATLPDVKTVGVMGDER
                     TYAYLVGLRAVTSSDGMTSDWYKMPYDVLERISNRIINEVDGVNRVVYDITSKPPGTI
                     EWE"
     gene            19194..20624
                     /locus_tag="KR294_000262"
     CDS             19194..20624
                     /locus_tag="KR294_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBH0238380.1"
                     /translation="MILNQIFIEAGGIMRNKIIIGITFSLVLLMSGCASKQTAEINVL
                     ATTDLHGVIPYELTSYVKEERKKDKNLTLVDAGDFFDSGEVFGSSMDSYFSARYKDGD
                     NNTESYIETPISKDMKEVGYDVAVLGNHEFISNNKFYLDNMISDFEKQKINILSANTY
                     KKNGDSYTKPYIIKNINTPEGNVKLGILGLTIKEVGERKQWKDGKLVDSKSLELKDQE
                     GYNGELYMNDLVEDAKKWVGIMEKEKPDIIVAVAHTGEKPKKPKNPGNRIQDLAQQVD
                     GIDAIVAGHNHVQIEQHDYKNKSGENVIVTEPGKHGECISKINFKLEKNNDKWNIVDK
                     SSKLIKFEKNQESDKFGEFISSINKVSKDKKEIRLSEVKTPEWDKIYVFKSGTSADDI
                     YKTIGYKWRNISSPKGDDMVQIVVMNNNKPVSYVYGEAEVMPINIKCDESEYKDNVVT
                     IYPNKNDKFKIEKGKQEYSINLKHIQ"
     gene            complement(20772..21122)
                     /locus_tag="KR294_000263"
                     /pseudo
     CDS             complement(20772..21122)
                     /locus_tag="KR294_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904812.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
     gene            21117..21638
                     /locus_tag="KR294_000264"
     CDS             21117..21638
                     /locus_tag="KR294_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HBH0238381.1"
                     /translation="MFSIGGGYAIILLIQEKVVNQTGWISEKMFTDIITISQMTPGPL
                     AVNTSTFVGLQIGGFWGAVAATLGCVLCGVVISLFLYNFFQKHQNSTYIFEILNGLKS
                     ASLGLIISAAATIIILALFGTNKVYFNSIFEMLNWTALIIFFVTLLIVRKWKINPIVI
                     IIISGILGIFFYL"
     gene            complement(21767..22561)
                     /locus_tag="KR294_000265"
     CDS             complement(21767..22561)
                     /locus_tag="KR294_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBH0238382.1"
                     /translation="MIFCNSFITRKSSMNIVVTHTPIVTTLEMQKAYEPLAKHNVNIF
                     AFDFSGTGKSDGYEKDFSRNSIVKDLDSVITYIEKNYSSNIHLYGNTGIGGMFAQYYA
                     CSDNKLKSFAQFACVDYKNTTGVGYTYLTVKLLNFFFKFLPNFHITVKPPKYKGYNEV
                     YDNEFYKIFEKKNPHIWKNSTKIINTMLECFIAKDSKIKDGVNIPTLVFKTLHDRYFK
                     TQYFDSYYNSLKCKKKLVEINNVHNSYYIDSEKFCQEAYDWFVENQ"
     gene            complement(22785..26198)
                     /gene="uvrA"
                     /locus_tag="KR294_000266"
     CDS             complement(22785..26198)
                     /gene="uvrA"
                     /locus_tag="KR294_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HBH0238383.1"
                     /translation="MKINNYKNQSIITNPKKFENKYQDLPKTPIELLKVVQSLVIHGD
                     QGKLYGISFNKQQSDEELLRTIPQMLKRIFEINSNPLTIPRNPKQRLVGMCRDYSLLL
                     VSLLRYRGFEARMRAGFANYFESELTYEDHWLVEYYDTLTKRWIRIDAQIDDIQKNYF
                     QINFDTHDVGKTDGFLTGSEAWIRCRQGHAHQDDFGYNKNWKGWHSVKGNLLHDFNNM
                     IGLELLPWDLWTELSSKKYNQLTRAEKNLLDEMAEILSSGNIKIEDLNLLIEKLPEDY
                     LKSIFSQLKILGISEIKELGNPLELEKKFKFTKSINKSIKNSLCHNKSSIYLKGGRQN
                     NLKDVEVTIPKNQITVITGVSGSGKSSLAFDTIYEEGKRRYFENLSNGAKLSEQLQKP
                     EFDLLQGLTPTIAIEQKKGSQNPRSTVGTLTSIWDYLRMLFVSIGKSYCPYCKIPLEK
                     KNNTKNYCPHCQTIFSKINTSTFNANSHTGACHDCNGLGFTYQVNPQLIVKDPTISIL
                     DGATYYFGKLKGKKPNGNWMVGELYAIAKDKNIDLDIPWNELPRDFIDAILYGTDDKI
                     YEFSFESKIRRPASGAINHIQRLFRESSSENNTLHQYMNKIPCNTCGGELLCIEARFT
                     TIKGYRFPELTKMTIEQLWNWLCELPNQLQKNELSLVNDILTELKIRVSYLLKVGLSY
                     ISTDRTAPTLSGGELQRVRLSSQLGSELVGLTYILDEPSIGLHPRDHNLIIKMIEELR
                     DKGNTVIVVEHDKDTILSADYIIDVGPSAGTKGGFIIAEGTTQEIIKNPNSITGKYLS
                     TYNKISSQNKIIPSKWLSLKGCHANNLKNIDVEIPLNCMCSITGVSGSGKSSLVFHSL
                     LPALEEKLKQKSIPDKNYTEFTGFDAIDDFILMDQTPIGKSSRSTPATYINIFDEIRS
                     LFAETPQAKQKLLDESYFSFNSKKGQCPNCQGLGKTKIILQYMADQWVTCSECQGKRY
                     QKEILSIQYKGKTIADILDMEVAEAKTFFSDCSDIYRKLSLLDEVGLGYLKLGQNTLG
                     LSGGESQRIKLAKELGTKTKKRMLYILDEPTTGLHFKDIENLLITFRKLVNEQHSLLI
                     IEHNTEVIRASDWIIDIGPDSGINGGEIVASGTPDEIKINPNSITGHFI"
     gene            26517..28751
                     /locus_tag="KR294_000267"
     CDS             26517..28751
                     /locus_tag="KR294_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBH0238384.1"
                     /translation="MKLSRYKKNSLVLSIILCSLIISILVITVFNTVKLHNISNKQSK
                     NYLNDVSTQIVMNVDSKIKFILSDLRIMADFIKQYEGDSRYEYLSKRKTSYKYYDVGI
                     IDLEGKAEFLSGKKFDLKNTVSYKKGIEGKEYSEVIESMGFVLYSVPIFNDNHEVSSI
                     LIGVSNKESMNEILNIDNFNGKGTIEIINSKGKPLFIGKNTELIKDLSHKYKSSGDEP
                     WAQKMLEDFKNDKSGNITITSSKGVQCLLTYHPITRGLNDWHFLLIVPEDAVLGELNK
                     LNSFTITMTFIITCIIGIITLILYIIRRKYVNQIENIAYLDSITNGINSTKFSMLVKP
                     LISESPDSTYMMIAMNIKDFKLINDCFGSEKGNMTLKHLYNILYKNIDENEEFVCRHD
                     ADLFYLLIKNRPVLEALELLYKIEADTNYFNKNRENPYFLRLSVGIYTIENHNEDLIT
                     IQDHANTARKSFNKTHQSDFSFYSDIERKRLISEKEISNLMEKALENKEFFMCLQPKI
                     DIKSGKISGAESLVRWKNSEKGIIYPSDFIPLFEKSGFICKLDLYILEETCKLISKWI
                     KEGKEVLRISVNVSRQHLNDKLFLEKYKHICNKYNVPTCLIDLELTESIFLENPEAID
                     IIEDIHSNGFKCSIDDFGFGYSSLGILKDFKVDIIKLDRSFFVSKNNIDRGKVVIKSI
                     IELSKRLGMKVTAEGIEELEQVEFLKNVGCDYIQGYVFSKPLLISDFENFAYENNKIK
                     NIHY"
     gene            29007..31037
                     /locus_tag="KR294_000268"
     CDS             29007..31037
                     /locus_tag="KR294_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH0238385.1"
                     /translation="MISGRMLLIMNFLKGKNKTSYKDISKQLSIEERKVRYDINNLNI
                     VLRSLNKSVIQKMNKGVLIIPDDFQVVCINNNEYVFSLTERVSIMKIISMFKIDNLNL
                     EKLSKEFQVSRSSIKNDLNVLSSELERNQITITYDKSFKISGEEDIIYKQRLNILKSY
                     SYLFGKEKSDLSVFEKYLVNVIEKIFKGIYLIDIYNWSMNLLLQMGWTLNDESFTWYV
                     SNIFLFTWYIHSDEKHPLESASLSEPCFENKFDQEFETIIQKKLTKEQIFLLKSFVFF
                     TNKYASLNEDMDLISTEIIVQDLIYNMSEILEISFKEDMILYKGLLNHIAPLIERIKQ
                     NIQIYEELLHVIPDKYQYVLEATKVSIQKNRVLSQIKNENETILLAIHFLGSIHRNER
                     NNYKNILLVCGFGYGVIAMLKDSLVNDYQINIVESIPSYKLQDYKDWESIDFIITTSK
                     IVIDLPKTIIEINPFLQEEDYLKFEEKGIKRKNVLTNYMSIKKRLDFLEEDAQKRVLS
                     IICQELGYSDERILFRQLNLSDLIGIDTIRIIDGDMKWEDAVKFSSNILANCDFVSAQ
                     YAENIIDILKNVGFYAVKDNEFALLHGNDSSLVKVSSISLLICKEAVSFGDKKVKIIF
                     CLASRDKKEQIPAIINLTKMVYKTNFIAMLESAKTKEEAEVLIHKYEKEVTV"
     gene            31034..31486
                     /locus_tag="KR294_000269"
     CDS             31034..31486
                     /locus_tag="KR294_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH0238386.1"
                     /translation="MNKLVNVKCSFKIHVNSKEEAIISLVDVVSKEGYLIDKNQFLKD
                     VLKREETLSTYIGHGIGLPHSQSVGVKNSCITIGKLDTPIEWTEEGEKVDLIFLISVT
                     KDNENNLHLKILSKLARLLMHESFRNQIRCSDEQTVYNLIKEKIEEED"
     gene            31488..32543
                     /locus_tag="KR294_000270"
     CDS             31488..32543
                     /locus_tag="KR294_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit EIIC"
                     /protein_id="HBH0238387.1"
                     /translation="MRILKFLQKHLMTATSYMIPFVVAGGILFALSVTLSGQAAVPET
                     GWLAKLNQIGAAGLALFIPILGGYIAFSMADKPGLAPGMIGAYLAKEVNAGFIGGIIA
                     GFIAGFVVLQLKKIKLAPTMRTLGSIFIYPLVGTLITGGIIVFLIGEPIASFMTWMTN
                     WLNGMSGVSKIPLGGILGGMIASDMGGPINKVAATFAQTQVDTLPYLMGGVGVAICIP
                     PIGLGLATLLFPKKFSKEERDSGKASLLMGCVGITEGAIPFATSDPVRVIPCIMAGSI
                     VGNIMAFLLGCLNHAPWGGLIVLPVVDNRLGYIASVLTGAVVVAVLMKLVKKDVKEDE
                     EIEEDLDESIELIFEEL"
     gene            32610..32918
                     /locus_tag="KR294_000271"
     CDS             32610..32918
                     /locus_tag="KR294_000271"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose-like transporter subunit IIB"
                     /protein_id="HBH0238388.1"
                     /translation="MKIVAVTSCPSGVAHTYMSAESLELSAKKFGIEIKVETQGSSGI
                     DNELSLKDIDEATCVILTNDVEIRNMERFKGKKVVRMSVSEIIKKSDALIKKIKDTFQ
                     "
     gene            33022..34287
                     /locus_tag="KR294_000272"
     CDS             33022..34287
                     /locus_tag="KR294_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II D-tagatose-bisphosphate aldolase,
                     non-catalytic subunit"
                     /protein_id="HBH0238389.1"
                     /translation="MKKLPIKTVVQRLLNLQEEGKSATLLGIGPMSPNLLQASFELAK
                     DDDFPLMFIASRNQVDADELGGGYVNGWNQETFTKDIKKVADKVGFDGLYYLCRDHGG
                     PWQRDKERNDHLPVDEAMELGKKSYLADIEAGFDLLMIDPTKDPFEIGKVIPLDVVLE
                     RTVELIEYCENERKRLNLPDIGYEVGTEETNGGLTSTETYETFITRLKVELDNRGLPM
                     PTFIVGQTGTLTRKTEQVGTFNFRNAYDLAQMAKKYGVGLKEHNGDYLDDVTLLEHIP
                     SQIIATNVAPQYGTEETRAYLKLAEVECKLEKEGLVEKTSNIRHVLLVNAIECGRWRK
                     WVVGEQKNLTTEEIFKDEVLSNEILDIAGHYTFNNDDVKKEIEVLYDNLSKNNIDGQR
                     FVVDHIKRPLRDYAECYNLKGVTTRILNK"
     gene            34375..35091
                     /locus_tag="KR294_000273"
     CDS             34375..35091
                     /locus_tag="KR294_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBH0238390.1"
                     /translation="MINLIFDVDDTLYNQLTPFYTAYNKVFSSIKDISIEDLYMSSRK
                     YSDEVFHMTENGEMPIKEMHIYRIMKAFEELGNSITEKDAQSFQDEYIYQQSQITLIP
                     EVERILNFSKERNINLGIITNGPSNHQRMKLKQLNIENWVDKSNIFISSEVGFSKPDT
                     NIFRVAENVMNLDRENTYYVGDSYRNDVLGAKKAGWKSIWLNHRGHEVEELFYKPDFV
                     ILEHKDLISLFIKICSYKNM"
     gene            complement(35286..35579)
                     /locus_tag="KR294_000274"
     CDS             complement(35286..35579)
                     /locus_tag="KR294_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat protein"
                     /protein_id="HBH0238391.1"
                     /translation="MRNMIENLIKNNTYIDDKVIMLSMLSSAKASANMYLNSALTSST
                     PELRAIYSASLTQMVEGHTALTELSINKGWVKPYDKPIQQLTCSYKESQNVID"
     gene            complement(35585..35800)
                     /locus_tag="KR294_000275"
     CDS             complement(35585..35800)
                     /locus_tag="KR294_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0238392.1"
                     /translation="MRILSETEKISLAAVIKMESDGLLMQRAINMLISDEDLKRQSES
                     SILATEGRIKAMQQFIVENEILISEEV"
     gene            36249..36647
                     /gene="tnpA"
                     /locus_tag="KR294_000276"
     CDS             36249..36647
                     /gene="tnpA"
                     /locus_tag="KR294_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011291581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HBH0238393.1"
                     /translation="MYKSNKNIVYDCKYHIVFCPKYRKPVLVGEVEKMLKEILPYKAD
                     ELGAEIIEMETDKEHVHLLISCDPQYGIHKVVKGLKGFSSRVLRENFPHLKSSMPSMW
                     TNSYFVGTVGSVSLEVVKQYIENQQVRTKK"
     gene            36644..37807
                     /locus_tag="KR294_000277"
     CDS             36644..37807
                     /locus_tag="KR294_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBH0238394.1"
                     /translation="MIKTHRVKLNLTRTQFELVREKQMESANCWNYIVNLSKEYYFEH
                     KQWIKKNDIQKLIKGKYNLHSQTIQAISDKFDANRKTISELRKKGNTKAKYPYKTKKF
                     YIIPFKASAINRNAKGNLKLSMSKGRYLELDFNVENIKTAEIVWRNGYYLYYTFDNEL
                     NGVVAKGTNTVGVDLGEIHSIASVTNEGVGLILSNREGRSIKQFRNKMYAYISKRLSK
                     CKKGSRQSKKLWRLKNKIRSKTDNQLMNLYHQTTRKFIDFCVEQKVCEIVLGDIKGVE
                     KDTKKKKRLNRVNRQKISQMEYGRIKDYIKYKAKEQGIEVKLVKENYTSQTCPKCSKK
                     HKPTGRTYSCTCGYETHRDIVGAWNILNKKHKYGLVDFRINHKQPINLKVSTV"
     gene            complement(38191..38703)
                     /locus_tag="KR294_000278"
     CDS             complement(38191..38703)
                     /locus_tag="KR294_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBH0238395.1"
                     /translation="MLEVIKNRRSIRTYIDKNIEEDKITEILKSAMQAPSSKNAQPWE
                     FIIVDDKELLKQLSKSQHRAKHIEFAPLCIVVLGNRDKFLKPGKWIQDLGACTQNLLL
                     EVTNQGLAACWAGVFPKNKVVNKVRQTLDLPLKLVPYALISIGYSEEKNEFIDRFDEN
                     KIHRNVYKNR"
     gene            39153..39629
                     /gene="purE"
                     /locus_tag="KR294_000279"
     CDS             39153..39629
                     /gene="purE"
                     /locus_tag="KR294_000279"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HBH0238396.1"
                     /translation="MKVAVVMGSKSDYPKLEEGIKLLEKYGIEVVARALSAHRTPEQL
                     SIFLKEIEDDTDVIIAAAGKAAHLPGVIASQTLIPVIGLPIKSSTMDGLDSLLSIVQM
                     PKGIPVATVTIDLGLNAALLALQIMTLKYPKLKEDLKSYREEMAQKVLEDDKNLRG"
     gene            39635..40333
                     /locus_tag="KR294_000280"
     CDS             39635..40333
                     /locus_tag="KR294_000280"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HBH0238397.1"
                     /translation="MLLYEGKAKQVYSTDNENEYVVYYKDDATAFNGEKKAEISSKGI
                     LNNKISTIIFEMLKENNINTHFIKSLSDREMLVKKVEILPLEVIVRNIAAGSICKRVG
                     LEEGVVFDEPIFEISYKNDAYGDPMLNDDYAVAMKLATREELKFLREETLKINELLKA
                     FFLKLNLKLVDFKIEFGKDSEGNIILADEVSPDTCRLWDVNTNEKLDKDRFRKDLGDL
                     VEGYTEVLSRMNNK"
     gene            40345..41712
                     /gene="purF"
                     /locus_tag="KR294_000281"
     CDS             40345..41712
                     /gene="purF"
                     /locus_tag="KR294_000281"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HBH0238398.1"
                     /translation="MCGVLGIYSNKDVTKELYYSLYSMQHRGQESCGLALLDDGEIKY
                     KKDMGLVGDVFKENELSKLKGNIGIGHVRYSTAGGSHVSNCQPLVGSCRKRQLAIAHN
                     GNLVNANYLKDMLEEDGYMFQTNSDTEVILYILARYYKGDIVESLKVTMDYIKGAYAL
                     VIMSQEELVAVRDPHGFRPLVLGKKGDEYIFASENCAIDILGGEVIRDVEPGEIIVVK
                     DGELKSYFYSENYKPVKKSCIFEHIYFARNDATIDNVNAYEFRIKCGERLAQNETVKA
                     DMVVPVPDSGWPGAIGYANASGLKISEGLVKNRYVGRTFIKPTQEEREIAVKIKLNPL
                     STIIKGKSIILVDDSIVRGTTSKQLVKSLREAGAKEIHLRITSPPVAYSCYYGIDTPN
                     RSKLIASSNNVEEMREYIGCDSLKFLDIEGMLDATEHKSTFCKACFDGEYPVKKIDKE
                     ELLSC"
     gene            41706..42782
                     /locus_tag="KR294_000282"
     CDS             41706..42782
                     /locus_tag="KR294_000282"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HBH0238399.1"
                     /translation="MLTYKESGVDIDEGNRAVDLIKGKIKGTYDGNVVGDLGNFSGLY
                     SLKDFVGMKEPVLLASTDGVGTKLKIAQMMDKHDTVGIDLVAMCVNDLICQGAKPLFF
                     LDYIALGKLVPEHIEKIVGGIADGCKMSGCALIGGETAEMPGMYGEDDYDLAGFSVGI
                     ADKEKIVSGNNVKSGDVLVGISSSGVHSNGFSFIRKIFLETYNYKMEQYVEELGMTVG
                     EALLTPTKIYVKLALDVLAKHDIKAIAHITGGGLIENITRVIPKGLGLDINKKSWEKP
                     PIFKMIEGFNAVDERELHKSFNMGIGLVLIVDKENADDVVNFINNRENDNAAYVDKKY
                     SELLEDKAYIIGEVVDSHEGVELC"
     gene            42776..43369
                     /locus_tag="KR294_000283"
     CDS             42776..43369
                     /locus_tag="KR294_000283"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HBH0238400.1"
                     /translation="MLNIGVLISGGGTNLQAVIDGTESGEIKGQVKVVISSKQGAYGL
                     ERAKNHNIKAICETDEDKIIEILKENKIDLVVLAGYLKIISPKLVNEFRNKMINIHPS
                     LIPSFCGAGFYGEKVHQGVIDYGAKVTGATVHFVDEGADTGPIIMQDVVKVNQDDDAK
                     TLAKRVLEVEHRILKESISLFCENKLKLQGRRVFINE"
     gene            43362..44894
                     /gene="purH"
                     /locus_tag="KR294_000284"
     CDS             43362..44894
                     /gene="purH"
                     /locus_tag="KR294_000284"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HBH0238401.1"
                     /translation="MSKRALISVTDKTGVVEFAKELNKLDYEIISTGNTFKTLKENGV
                     NVMQVEDVTNFPEILDGRVKTLNPYIHGGILYKRDKESHVETVNEHKIHSIDLVAVNL
                     YDFEGTLKAGKSHDEIIENIDIGGPSMIRSAAKNYKDVIVVVDIKDYDSIIEKLKTDT
                     MTLEDRKKLSYKAFSTTGRYDALISSYFAGEVGDTYPDILNLTFQKEQTLRYGENPHQ
                     NGFLYSQSNAKNPILNYEQLGGKELSFNNLNDLHGCLEVMREFKDSEEVVSVAIKHAN
                     SCGVGLGKDAFEAYTKCYEADKVSIFGGIVGITSTIDKATAEKLNEIFLEIVVAYDFE
                     PEALEILKQKKNLRILKLAKIENSLQPYEMKYLDGKLLIQDRNNILAEKSENVTKEKP
                     TDAQLKDMEFGMRVVKNMKSNAIAVVKNGQTLALGCGQTSRIWALKNALENNKDKDFT
                     GAVLASDAFFPFDDCVTLAHEYGISAVVQPGGSIKDKDSIEACDKYDMVMVFTGIRHF
                     KH"
     gene            44905..46155
                     /gene="purD"
                     /locus_tag="KR294_000285"
     CDS             44905..46155
                     /gene="purD"
                     /locus_tag="KR294_000285"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HBH0238402.1"
                     /translation="MKILVVGGGGREHAICWKLSKEKNVEKIYCAPGNAGIANVAECV
                     NIGDTNIEELLKFAKENEIGLTIVGPEVPLVMGIVDEFEKEGLRVFGPNKKCAQLEGS
                     KAFSKEFMIKHNIPTAKYKEYTNLEEAISEIDSFGYPVVIKADGLAAGKGVVIPENRE
                     DAIATLKEMMSDKKFGAAGDKIVIEEFLKGIETSILAFVDNDTIVPMASAKDHKKVNN
                     YEQGPNTGGMGTFSPSEIYTEELANKVKETVLEKTLEGFKKDGLNFKGILFVGLMITE
                     DGEKVLEYNVRFGDPETQSVLFRLETDLHEIMEAILDNKLKDIEINYSDDEAVCVMLT
                     SGGYPDSYEKGKIITGLENLDDDIVVFHSGTKMFDGNLVTNGGRVIGITAKSTRVKDA
                     AEKVYENIKKINFEGMHYRTDIGR"
     gene            46180..49986
                     /locus_tag="KR294_000286"
     CDS             46180..49986
                     /locus_tag="KR294_000286"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HBH0238403.1"
                     /translation="MLNTENKDSMVRRVLVEKREGFDLEAKALKKDLVESLHIDNIEN
                     LRILNRYDVEGISEEVYENAAKTIFSEPNLDVVYYEEIPKLNDERVFAIEFLPGQYDQ
                     RGDWAAQCVQIVNQGIRPAINTAKVYILSGKITDEEFSKIKDYCINPVDSREASLEKP
                     ETLKMETEIPTTVEVLDGFIDLDENGLRTFVSEKGLAMTLGDLQHVQKYFKDTEKRNP
                     TITEIKVLDTYWSDHCRHTTFMTEIENVKIEDGKFNDIVKEAYQMYLNSRDNVYVNRH
                     KDICLMDIATVAVKELKKNGKLNDLDESEEINACSINVDVEVDGKMEKYLVMFKNETH
                     NHPTEIEPFGGAATCLGGAIRDPLSGRSYVYQAMRVTGSADPRTTLEDTLPGKLMQRK
                     ITTEAAHGYSSYGNQIGLTTGQVAEVYDENFVAKRMEIGAVIAAAPKENVVRERPEAG
                     DVIVLLGGKTGRDGCGGATGSSKEHSEESILTCSAEVQKGDAPNERKIQRFFRNKEVA
                     QMIKRCNDFGAGGVCVAIGEIADSLDINLDLVPKKYDGLDGTELAISESQERMAVAIK
                     KENKDKFIQLAVEENLEATHVATVTDTGYLRMFWNGKAIVDINREFLDTNGVKQTTDV
                     HVTKVDEENTFFSSNEIVKDVKCASMKDKFTKVLSDLNVCSQKGLVEMFDNTIGGNTV
                     LMPFGGKYQATPTQGMVAKIPVLGGETNTSTIMTYGYNPKVGKWSPFHGALYAVVESV
                     CKLVAIGGNYSTTRLTFQEYFEKLGNNPEKWGKPFSALLGAFYAQSKFEIPAIGGKDS
                     MSGTFKDIEVPPTLVSFAVDTVDAKKVVSPEFKKADSKVVMLCVNKAENDVVDFEELK
                     RNLDKVRELIHGNKVLSTYALGFAGVGEAISKMAFGNKIGFKFSEEAEKAFTDNKLFE
                     ASYGNIVLELANDDLSMLEGYNYVVIGSTVKEASIFIKGEELALDELYKAHCSTLEPI
                     FPTKTEEVKSKIETISYISQGEAKKSSLSIATPRVFIPAFPGTNCEYDSARAFERAGA
                     NASIRVFKNLTYKDIEDSIDTIVNEIKSSQIIMLPGGFSAGDEPDGSGKFIATVFRNP
                     RVQEAINEFLTQKDGLMLGICNGFQVLIKLGLVPYGEIRVPSESAPTLTYNNIGRHQA
                     KIARTRISSNKSPWLAQTNVGDIHNIAISHGEGKFVASEDVMRELIANGQVATQYVDF
                     NNEATYDIEFNPNGSFYAVEGITSADGRVFGKMGHSERIGEEVYKNIIGEKDQKIFES
                     GVKYFR"
     gene            50192..51064
                     /gene="rfbD"
                     /locus_tag="KR294_000287"
     CDS             50192..51064
                     /gene="rfbD"
                     /locus_tag="KR294_000287"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HBH0238404.1"
                     /translation="MKILITGSNGQLGKELVNQLEAINQSINQPKYVILATTRSDLDI
                     SNQTNVDNFILHNKPDVVVNCAAYTKVDACEDNIEIAYKINALGVRNLAIASEKVNAK
                     LIHISTDYVFNGFSKYPYREDNKTEPNSVYGKSKLMGEKFVEQFSHKYFILRTAWLYG
                     NGNNFVKTMIKLSLENKEVNVVNDQFGTPTSTVDLAKIIIRIMETEHYGVYHATCEGE
                     CSWYDFAKKIFKLKNIDIKVNPIKSNEFKCKAPRPLYSVLDNFMLKLIGLNSFRKWEE
                     SIEEYLERYDINEK"
     gene            51173..52042
                     /gene="rfbA"
                     /locus_tag="KR294_000288"
     CDS             51173..52042
                     /gene="rfbA"
                     /locus_tag="KR294_000288"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HBH0238405.1"
                     /translation="MKGIILAGGSGTRLYPITKCISKQTLPIYDKPMIYYPMSVLMLA
                     GIQDILIISTPRDIKAFEELFGDGSSLGLNITYAIQEKANGIAEAFIIGEEFIGNDRV
                     SLVLGDNIFYGYGFSERLENAVKRKGATIFGYHVSNPNSFGVVEFDKDFNVLSIEEKP
                     TVPKSNYAIPGLYFYDNDVVEIAKLVEPSDRGELEITSINSEYLKRGKLKVELLGRGM
                     AWLDTGTHKGLLDASNYVEVVQTRQGLYIACLEEIAYTKGYISREQLMKLAKPLIKTE
                     YGQYLLKLASEDM"
     gene            52091..52648
                     /gene="rfbC"
                     /locus_tag="KR294_000289"
     CDS             52091..52648
                     /gene="rfbC"
                     /locus_tag="KR294_000289"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HBH0238406.1"
                     /translation="MGKINVIKTKIEGLYIVEPNVFYDERGYFMESYNKKDFIEQGLD
                     MCFIQDNESSSRKGVLRGMHFQVKYPQGKLVRVTEGEVFDVAVDLRKDSQTFGKWEGV
                     ILSDKNKKQFYIPEGFAHGFLVLSEKAVFSYKCTNYYYPEFENGFIWNDKQISIEWPL
                     KGIEEIFLSEKDKKQKSFKDICTRR"
     gene            52686..53669
                     /gene="rfbB"
                     /locus_tag="KR294_000290"
     CDS             52686..53669
                     /gene="rfbB"
                     /locus_tag="KR294_000290"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HBH0238407.1"
                     /translation="MKKILITGGAGFIGSNFIHYMLNKYVDYFIVNLDLLTYAGNLET
                     LIEIQDNSNYKFVKGDISNREQVYKLFEEERFDIVVNFAAESHVDRSVENPDLFIKTN
                     IIGTQVLLDASIKYGVKRYHQISTDEVYGDLPIDRKDLFFTEQSSINPSSPYSASKAS
                     ADLLVSSYYRTYGLLTTISRCSNNYGPYHFPEKLIPLMILNALENKQLPVYGNGENVR
                     DWLHVYDHCTAIDLIIHKGNIGEIYNIGGHNERSNLEVVKMILNLLGKSEELISYVND
                     RPGHDLRYAIDATKIENELGWKAKYDFDLGIKETVKWYIENESWWKAVLSV"
     gene            53699..54367
                     /locus_tag="KR294_000291"
     CDS             53699..54367
                     /locus_tag="KR294_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HBH0238408.1"
                     /translation="MNEISSLINILALTQLSGSNTTNQCNCTYNNSSGFDMIMMTLLK
                     ALSQNNQHTSNSYNLLSNSENLFNELDNVVNNTTSRFIDVDTKDKNVKLRIENAVDQA
                     SKKYNVDSNLIKAIIKVESDFNPNTVSSAGAKGLMQLMPENCRDLGVTDPFNIEQNID
                     AGTRHIKEYIDMFGGSIEMGLMAYNGGPGRMKSRGVESISDLYKMPKETQNYIPKVMK
                     YYRG"
     gene            54376..54804
                     /locus_tag="KR294_000292"
     CDS             54376..54804
                     /locus_tag="KR294_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaaR family protein"
                     /protein_id="HBH0238409.1"
                     /translation="MGINIDKLNISPSINMEVKKLKESNKFSDKLNSLKQSSSLEDIK
                     RNLESVKKAGERLVLTQNYGDISIYKNAVKEYLKSVVDNMYSLDKNSSFWEHQYYKNV
                     KIVDSKLEDMTSKLISEEKENIDIVSTVDMIQGLLIDMYR"
     gene            54828..55142
                     /locus_tag="KR294_000293"
     CDS             54828..55142
                     /locus_tag="KR294_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliM/FliN family flagellar motor switch protein"
                     /protein_id="HBH0238410.1"
                     /translation="MNSKKEDIYELNFGQLIEEKSGVIEENQNVFNAKVNVAVSIGNT
                     TETIKNILDLKEGSIIKLSKNVDEKLDIYANDRLFAYGESIITNERLSVRLSKIEDPD
                     VN"
     gene            55294..55569
                     /gene="flgM"
                     /locus_tag="KR294_000294"
     CDS             55294..55569
                     /gene="flgM"
                     /locus_tag="KR294_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis anti-sigma factor FlgM"
                     /protein_id="HBH0238411.1"
                     /translation="MDIKNVSSNIVVNNYLKNTSGIKKVEEVKKINKTDKIELSKFAK
                     EMASVSNMSDENIRNKKVDEIKNALENGTYKIKPKEIAKKMIEDMRG"
     gene            55574..55990
                     /locus_tag="KR294_000295"
     CDS             55574..55990
                     /locus_tag="KR294_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FlgN"
                     /protein_id="HBH0238412.1"
                     /translation="MITDLKVIIYEEKNIISKMMELLKEQFDYIVEKDLENLNMLNPK
                     LEDISRELASIEIKRRQLFGDDISMSEVVENSNDGYLKEIYTDLKHILALAKNQQESN
                     DSLIKKELIFTKKMINFIKPADKQTTTYNSYGNIRK"
     gene            56008..57318
                     /gene="flgK"
                     /locus_tag="KR294_000296"
     CDS             56008..57318
                     /gene="flgK"
                     /locus_tag="KR294_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-associated protein FlgK"
                     /protein_id="HBH0238413.1"
                     /translation="MAGLFSILNTANSGMNAHQKAIQTISHNISNLDTDGYSRQRTEF
                     ATNSPMYMPSLSNSIARGQLGTGVHVTDVTRARNSFYDYQFRAEAHKYGKTVSKYDYY
                     NTIETILNEPSDYGISAGIDDFFKGWESLSKDINSDSKKSLVVENASNLATLISESYK
                     KLDKLKEDIDSNIDTEIKQINDMLKSLEDLNKSIDIISGSGSTPNDLLDERDRILDNL
                     SFKLDFENSDVKNMLADGKLELNELKNPDGTWKTGISGTLQGLFEMHGKIDTYKSDLK
                     DVSDGLAKQINDVYNTSAGITVTDFFITSNVDGEDIIKINPAIKSNPNELKLTADEAS
                     KIAKLKDEKIDIGVAGGKVSTISDHYKAFAESIGLDSQKVNQDEANQRKIINNIDNSR
                     MSVSGVSLDEEMTELIKIQRSYQASAKVMSTAVQLLDVVINGII"
     gene            57337..58269
                     /gene="flgL"
                     /locus_tag="KR294_000297"
     CDS             57337..58269
                     /gene="flgL"
                     /locus_tag="KR294_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-associated protein FlgL"
                     /protein_id="HBH0238414.1"
                     /translation="MRVSTGMMSSSYLNSLQDNLQRLDKVNRQVNTTKEINKLSDNPY
                     KAIKILNSKSEIKTMETYVENCKDTGNWLETTDTALDQLGKLLSDIKKTLVASGDGAY
                     SDDELKTLSNETNEKMKEIANALNATHEGKYIFSGSNTGVPPVECIDNADGSVSLKFN
                     SSLNLNKLNDSLSMDIAQGISVDYNVKLSSLGFDPTKTDPFEELNNISKKLANPDADA
                     IKELTTTCLGDMEQLIENTVNVRSIYGTKANTVEAMKEKNDDSLIQLKDILSQNEEID
                     YGEKLVQLKAAELTYQASLQTGGKLFNVSILDYI"
     gene            58285..58677
                     /locus_tag="KR294_000298"
     CDS             58285..58677
                     /locus_tag="KR294_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar assembly protein FliW"
                     /protein_id="HBH0238415.1"
                     /translation="MMKVTLKKGILGFENLKEYELLDIEDNDYLKEFNSTEEEGIGFV
                     VVSPFEIINEYEIVLNQETIEKLEVKSPKDVVLFNIITLGQTFEESTVNMKAPIVINI
                     KTNFGMQIILQDDKYSIRHPLLRGDSGC"
     gene            58671..58883
                     /gene="csrA"
                     /locus_tag="KR294_000299"
     CDS             58671..58883
                     /gene="csrA"
                     /locus_tag="KR294_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011987028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon storage regulator CsrA"
                     /protein_id="HBH0238416.1"
                     /translation="MLVISRKKDEAVLIGESIEVKIVGVDGNNVKLAISAPNNISILR
                     KEIYEKVKSENIKATNKNIKILKSLK"
     gene            58905..59300
                     /gene="fliS"
                     /locus_tag="KR294_000300"
     CDS             58905..59300
                     /gene="fliS"
                     /locus_tag="KR294_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export chaperone FliS"
                     /protein_id="HBH0238417.1"
                     /translation="MYGENPYNSYKQNAVFMASKEQLLLMLVDGAVKYTKIAKTAILD
                     KNTQKAHRELIRVQDIFTELMVTLDQNAGQWAKDMYRVYDFVRYELSRANIRKDIQII
                     DNVLPVIEQIKDTWHEADKKSKEERSRYK"
     gene            59300..59656
                     /gene="fliS"
                     /locus_tag="KR294_000301"
     CDS             59300..59656
                     /gene="fliS"
                     /locus_tag="KR294_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export chaperone FliS"
                     /protein_id="HBH0238418.1"
                     /translation="MELNLAELDKLSKEELLLMLVDGTVKYTNISKEALLNNDYLKAH
                     NELVRVQNIFTELMTTLDQDAGQWAKDMYKVYEFIKSELAIADENKDIKIIDDILPIV
                     KQIRDTWHEVYNQLKI"
     gene            59677..61200
                     /gene="fliD"
                     /locus_tag="KR294_000302"
     CDS             59677..61200
                     /gene="fliD"
                     /locus_tag="KR294_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar filament capping protein FliD"
                     /protein_id="HBH0238419.1"
                     /translation="MSSISPIRVTGLSGNFDMEGIIEASMIRDKEKVDKAKQEQQIVK
                     WKQEIYRNVIQESKDLYDKYLSVNSPNSIVSEKAYSSTRITSSDESIIVAKGSAGAEK
                     INYQFAVSQMAEPAKFTIKLNSSEPIVQQFPPNASGASSLTIGDVNIPISEQDTTSTI
                     VSKINSLCADNDIKASYSEMTGELIISRKQTGSSSDINLRVIGNDNLAQQIANDNGIT
                     FINDAGGNKVANVYGKNLEADVTDEHGRVTHISKEQNSFNIDNIDYNVNSKGTAKLTS
                     VTDTEEAVKNMQAFVDDYNKLMDKVYGLVTTKKPKDYPPLTDAQKEDMTTEEIEKWEK
                     KAKEGILRNDDELRGFVEDIQSAFFGDGKNIIALRKLGINESENYNKKGQISFNADTF
                     SKALIDDSDKVYKTLAGYSSNYDDKGMFEKLKDIVYEYSGSSTSKLPKKAGIEKTASA
                     SENVYSKQIAEQERNISRLVEKMNDKEKRLYAKYSALESLLNQYSSQMNYFSQAQGN"
     gene            61203..61538
                     /gene="fliT"
                     /locus_tag="KR294_000303"
     CDS             61203..61538
                     /gene="fliT"
                     /locus_tag="KR294_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FliT"
                     /protein_id="HBH0238420.1"
                     /translation="MDKLKEKLNLYKDISLQIINLIEKEEYIKISIKLGERQEIINSV
                     SEIDRNDFIQLYNRMELIEIDSRIRDILQGQLLEVKKELHEYKLTKQVNTMYYNLNRE
                     KVNIFNKKV"
     gene            61640..62512
                     /locus_tag="KR294_000304"
     CDS             61640..62512
                     /locus_tag="KR294_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellin"
                     /protein_id="HBH0238421.1"
                     /translation="MRVNTNVSALIANNQMGRNVNAQSKSMEKLSSGVRIKRAADDAA
                     GLAISEKMRAQIKGLDQAGRNVQDGISVVQTAEGALEETGNILQRMRTLSVQSSNETN
                     TAEERQKIADELLQLKDEVERISSSIEFNGKKLLDGSSTEIRLQVGANFGTNVAGTSN
                     NNNEIKVALVNTSSIMSKAGITSSTIASLNADGTSGTNAAKQMVSSLDVALKELNTSR
                     AKLGAQQNRLESTQNNLNNTIENVTAAESRIRDTDVASEMVNLSKMNILVQASQSMLA
                     QANQQPQGVLQLLG"
     gene            62605..64746
                     /locus_tag="KR294_000305"
     CDS             62605..64746
                     /locus_tag="KR294_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBH0238422.1"
                     /translation="MLLSIVMIVKNEEKILEKTLKSLTTLRNSIESELIIVDTGSTDD
                     TIKISKKYTEKVYFHNWNNDFSSMRNISISYAKGEWLLILDADEILIDSSTIVKFFKD
                     GLDKKFNSASIQLKNLYSYDKKLYGYCSVLRLFKNVDFRYHGKVHEQPIYKNPIFNNV
                     ADFEHYGYLFEDEEIRLNKVKRNEKLLFQELKENDNSPYTNYQLGKNFIILGKYQEAL
                     YYLEKSYELYSKLELAPGYLITSLVKTYLYLGKHKKCERLCLKYIKKDMNNIDIYYYI
                     AQAQVDLGKYENSIDSYKRYIYLLDNYEISTQANSLFSDTDTVGLRDEAIITLIKIYY
                     KLEKYEFVISEYNNIEDVEKKKNVYFSLFMSLYKLNRFEDIKNYYKEVSNSKIEKNSF
                     YRNIEEVINNIKEDEKEYVYKILCDIEGNYGILNQIRINKCVSIDKCKEILNEEKEII
                     YAYIIKIAFEEKIDLLDIFYEMEYVWIEKYLKYLLALERSFNLVLYKYIISRPNTSDM
                     EKIRVYKAISKVVLESISLSDEKYKEIFYLYIMYSYKYIRYIYSNLSDFELIKFVCND
                     LDKFTIEFKHLLDIKNKVNNANEKLEYIHSMRKLLNEYPFYNKIIKILIGELEENIKE
                     SEEFKDLKDSFIISIENMIETGKINDAKLLVDDYSKTFVDDIKILNIKGILYMFENKL
                     DKADFMLKKALSLDVENEDTIYNIEYLKSLR"
     gene            64770..66647
                     /locus_tag="KR294_000306"
     CDS             64770..66647
                     /locus_tag="KR294_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBH0238423.1"
                     /translation="MNIPIVVNEKSKDIIKDWQYTCTNEDIKFTSIIILTYNQIEYTK
                     LCIESIRKFTPKNKYEIIIIDNNSSDGTVEWLKGQSDIKSVYNNKNLGFPKGCNQGIE
                     LATGENILLLNNDVIVTPNWLYNLNKALWSQDNIGAVGPITNACSYYQQIDVDYKSIE
                     DMFIFAHKINKSNINLWKYRLKLVGFCMLIKKTVLDNVGVLDELFTPGNFEDDDLSFR
                     MIESGYKLLLCQDTFIHHFGSVSFKENRNKYTDIMYINRRKFETKWGFNPEYSGMIRT
                     DLISKIDDSLEANINVLEIGCGIGATLLEIKNIYKNASIYGIEISESAGKLAKYSADV
                     LIANIEKVKLDYKKDFFDYIILGDVLEHLIDPWKIVNELKQYLKKDGYLVSSIPNIMH
                     VSVLRNLVLGNFTYEDSGILDKTHLRFFTLNEITKMFNDSNYIINSITATSMPLSEID
                     NSFIDTICKESCKEMRQQYESYQYIVKASKILDTKRYSSISMINLKYALMRIDNELDV
                     DSNLSYIFDNYNITEPCFVDDIEYLIDTFVINKATLLNRLGVEAFNRGLGDFSINMFM
                     TVLEMDRDDIDSIYNITSVLCELEEFDTAYNLIKNSSEKVQSESDIQEILCFIEGKKY
                     E"
     gene            66640..68754
                     /locus_tag="KR294_000307"
     CDS             66640..68754
                     /locus_tag="KR294_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HBH0238424.1"
                     /translation="MNNDKICFITCVNDERLYEECLVYINSLDIPKNFSIETVALRGA
                     DSIASAYNKAMRETDSKYKVYLHQDTFIINKNFIHDILEIFKKNTDVGMIGVAGVKDM
                     PVNGIWWDSDKKAGKVYDSHTGKMDIYEFSNFEECFNEVMAIDGLIMITQYDVFWRED
                     KFDGWHFYDLSQSMEFRQNKYKVIVPKQNKPWCMHDSGVVNINNGYDEYRIKFVKEYI
                     NLDLYRENFYEFDKKKASTILKSNKHVMDCMKEELTEQLRLKNYKDVLGIVSKIAHFS
                     VFNHTGLYSCEECERALLECANNLPEIENTKLFTKKDLKRRKVLHVLSEGYSTGGHTR
                     LVKNWIEIDKDSVHSVVTTWQSDTLPDWLLKAINDSGGEVISLDLISDDYLKRAVALR
                     KIAYDWADIVILYVHMWDTIPVVAFGVDGKIPILHVNHYDSTFWLGTSIADIVIDFSE
                     TSQLITLDKRGIDKSEILPMPLKEKEVFSKSEVRKRYNLEDDVTIILTIASERKYNSV
                     NDINYFKIAKTLIENTDNTIIIVVGVDTENLYWKTLSNVTDNRVICFGTTANIDDFYK
                     ISDIYLESFMVGSHTSKLDAILYDLIPVKFKNEVSPIFTNMWNFIDKFDYKNIKEVID
                     MIRRYNTSEFDRDKIKAKQSEIKHFVIDKHCIEIKNYIDKIYNEVNHHKVKYDLYKND
                     EIEDYQLFVALYGYMVKNKNMS"
     gene            68763..69758
                     /locus_tag="KR294_000308"
     CDS             68763..69758
                     /locus_tag="KR294_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation glycyltransferase
                     FemA/FemB family protein"
                     /protein_id="HBH0238425.1"
                     /translation="MNNIHINKFEKSCEKNWDYFVENKSINGTFLQTRNFLNYHEEGK
                     FTDHSLIICKGEEILAVVPACETYEDGERIFFSHLGSTFGGIIIRSGFNDIRHVNAIT
                     NKLEIYLQEQNFDKVYLKNTSRIFCKEDTSLLEYFLFKNNYMFYDELSMFLELSKYKE
                     DILANFKYSKRRDFKYSLKNNLTFKRLYSDEDIVCFFNLLSNCLDSKGAKVIHSVEEL
                     LEFKNNRLKDIVEFYAVYIDDIMICGSMVFNFQERVYHTQYLASNSTYNKYYPMIFLY
                     YNLIKDALERNFKYLSFGISTLNRGKYLDEGLATFKEGFGSSAICNRTYYKNINK"
     gene            69850..71082
                     /locus_tag="KR294_000309"
     CDS             69850..71082
                     /locus_tag="KR294_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HBH0238426.1"
                     /translation="MKRLMILGSIKYFENIVMSAKREGIYTIVCDNRIDTPAKKICDE
                     AIDVDVFDFDKIKNIAIDKKIDGILTGFTDSLMKPYVYIANELNLPCVISCNQLESVT
                     NKAVMKNYFKNNGIPTTDYCIIESLKDLEKIQGLNFPLVIKPVDGYGSRGVYFVSNIE
                     ELIEKFEYSKEASQDGQVIIEEFYESEEIQGLAWVHNGESHVFYIGDRELVNIHTGRA
                     GKPDRLIYPSKYCFQYEEEIKSIYQNITQAFGIKNGPLYVQMLVGAYGIKVSEVMPRL
                     PGGCDYMAISQITDLDIGSLFANFSVNNEVNFDEIKKYNMHLSKCVYALPIYIRPGTI
                     KKINNIDKIENLDYVTQFLLLVKEGDTIGLYEDERQDCGRVYGVANNVFDANIKKKCI
                     HEMIEILDENNENMIENF"
     gene            71102..72046
                     /locus_tag="KR294_000310"
     CDS             71102..72046
                     /locus_tag="KR294_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase"
                     /protein_id="HBH0238427.1"
                     /translation="MKLITHEQIMSLNISQKQGYEWIKESFLTKKDCQLPPKISMVEE
                     GHVFYNVMPSLNHNHKIGGIKMVTRLPGRNPSLNSEIFLYNMEDAKLKAILDGNYITA
                     FRTAAVAALAIDTFAKKDFNTIAIMGLGVTASAIMNMLSYTLKDKNINIKLLKYKDQA
                     ESFVKKYEKNEQFSFEICDTHEELIVDSDVVISTVTYTDEYLSEFKWFKKGALLLPVH
                     VMGFGNVDYLFDKVYLDDYNHLKHLENIDRYKYSCEFYDVLSKQAKGRENDDERIISY
                     NIGLSIHDILFANKIYELCETLSCEEIELKEPKEKYWI"
     gene            72140..72547
                     /locus_tag="KR294_000311"
     CDS             72140..72547
                     /locus_tag="KR294_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxcM-like domain-containing protein"
                     /protein_id="HBH0238428.1"
                     /translation="MDKYNLIRFVSIGNEYIGNLVALESNKAIPFDIKRVYYIYDVPN
                     NVKRGFHAHKNLEQVLVCLNGSVKIKCYDGVKETIFNLHKNDVGLYIGTGVWHEMFDF
                     DEKTVLISIASEHYNEEDYIRDYKEFLKYLNNV"
     gene            72634..73725
                     /locus_tag="KR294_000312"
     CDS             72634..73725
                     /locus_tag="KR294_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS family aminotransferase"
                     /protein_id="HBH0238429.1"
                     /translation="MLVKFNNLLKQFQTHKEEYEQKIKDVMESGYYILGNEVKHFEEE
                     FANYVGSKYCVGLASGLDALIIAFRALGISKGDEVIVQSNTYIASVMGISINGATPVF
                     VEPNEYYNIDSSKIEEKINSKTKAILVVHLYGQASNMKDIQELCDKYNLYLIEDCAQS
                     HGAKYDGKMTGTFGDIGCFSFYPSKNLGAFGDAGAIVTSNEEIADKVKILRNYGSEKR
                     YYNKFVGYNSRLDEIQAGLLRVKLKYLNEIEIEKSKIVDRYLNEINNPKVILPKIENN
                     CTHVWHLFVLQVEKRDTFMEYLKKSGIESIIHYPIPPHLSEAYAYLGYKKGSFNIAEN
                     YSDKVVSIPLFIGMEDEEVSYIIKIINEY"
     regulatory      74034..74124
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            74533..74850
                     /gene="flgB"
                     /locus_tag="KR294_000313"
     CDS             74533..74850
                     /gene="flgB"
                     /locus_tag="KR294_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgB"
                     /protein_id="HBH0238430.1"
                     /translation="MNTYDIIKMGLDATNLRSQTIANNIANINTEGYKRHYITFEETL
                     NDAMPKIEEKTDNSKGLRVDGNNVDIEEEKVNQAMATLQYNALISFANGKIAMTKSII
                     SGR"
     gene            74858..75262
                     /gene="flgC"
                     /locus_tag="KR294_000314"
     CDS             74858..75262
                     /gene="flgC"
                     /locus_tag="KR294_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgC"
                     /protein_id="HBH0238431.1"
                     /translation="MSVFSGMRISASGLTAESLKMDIISSNVANINATRGPNGEAYRR
                     KVVSFEENYDNKLGMLGVKVTSVEDDKSPLKEVYDPSHPDAKPNGYVEYPNVNILVEM
                     TDLITASRAYDSNVDTLNAQKSMISKALEIGK"
     gene            75272..75589
                     /gene="fliE"
                     /locus_tag="KR294_000315"
     CDS             75272..75589
                     /gene="fliE"
                     /locus_tag="KR294_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-basal body complex protein FliE"
                     /protein_id="HBH0238432.1"
                     /translation="MPITQINNLMQGAKLDNLIGEAKPLTLNNKEEKKNFEDVIIDTI
                     DKVNFQQVTADDMKEKFIKGEDVSMHEVMLIGQEAQLSMQYLIEVRNKIHDAYQEMNK
                     VQI"
     gene            75614..77164
                     /gene="fliF"
                     /locus_tag="KR294_000316"
     CDS             75614..77164
                     /gene="fliF"
                     /locus_tag="KR294_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar M-ring protein FliF"
                     /protein_id="HBH0238433.1"
                     /translation="MITSFKNKIKEQVAKSRTKISSLKKGTKIALGIGVIAICLALVF
                     TAISASKNKYAVLFSELDAQDAADISAELESKKIDTKVKGSTIYVPRTEVDKLRLELA
                     PSLTGGSKGFALMDDSSSIGLTDEEFQIKKQRMIQGEIEKTIKSFPQVEDTRVHITFG
                     ESSVFEKEAVPGSAAVYLMLKPGTTLEKNQIKSVMALISGSVTNIPEKNVQVIDNKMN
                     LLSEGILEDENVDENNQPINSGISVDKNKASEQALNKQLEKSILEMLEPIFGKGKVKA
                     TVNADLSFDTAEKTEIKIDPDKVAIKETRSKNSSKSAANNVQGVDANMNNQGNNNGTN
                     TEDSLDESFEYETGKIETHTIVAPGELNRLTASVAIDGKIAKGVQADVEDIVNNAIGM
                     DGARGDTLSVVSMVFDPEGKKEAKQELEEIKKEGFKKNIIKAVIGVVAVIAVGAIGYL
                     IYKKRSEREDMDYEDEDYISKSDSVDRKDNPLLGDDPELTLEEAVKMYAEEKPDQVTE
                     IIKTWLNE"
     gene            77177..78247
                     /gene="fliG"
                     /locus_tag="KR294_000317"
     CDS             77177..78247
                     /gene="fliG"
                     /locus_tag="KR294_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein FliG"
                     /protein_id="HBH0238434.1"
                     /translation="MSTEITNVNAFDLSDINESDKNEKVEGEGLKKAAVLLMTLGPNV
                     SSDIIKSLPDKQVQKIGLEIANISSIASKERREILKEFVEINRAKDYVIEGGLEYARE
                     LLSNALGNVKANKLLEGISINTSTKPFKHIIKLDVKKILEILRNESAQTIAVLLAHME
                     PENGAEVLSYLDFDLQNEVAMRISSMGSISPEVIKVIESSLEDKLHSISGDDFNDYGG
                     VSTLVQILINSDRKTEKNILGTIEEQNPDLAAQIKSHIFVFEDIVKLDDISIQKVLKE
                     VTMKDLVYALKGVDDEISDAIYRNQSSRAADALKEEMEMVGVIKVTQVEASQQKIANI
                     VRKLEREGAITIVRNFGGDFVE"
     gene            78240..78971
                     /locus_tag="KR294_000318"
     CDS             78240..78971
                     /locus_tag="KR294_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar assembly protein FliH"
                     /protein_id="HBH0238435.1"
                     /translation="MNNKIIKSKKALYKGVLDLTIIDKVRVGESNVNKENDCRFRDEV
                     IKEAIESAEIKKNEILEEAKINAQNIEKQAYEKGYSQGQKNGYEDGYKESYDEYTQKA
                     KDEADFIKNQANLILLQANEKMTEYIKEKNKEIVRLAINMASSVLKKHFEDEESMSDL
                     LKQIIQDYEGSSSFIVRCNSFYKDNIEKEFELFKEETSLKSSVFVIADDSIDKGNAII
                     QKENGRIIVGIDCAMEKLKEELLGE"
     gene            78975..80294
                     /gene="fliI"
                     /locus_tag="KR294_000319"
     CDS             78975..80294
                     /gene="fliI"
                     /locus_tag="KR294_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein export ATPase FliI"
                     /protein_id="HBH0238436.1"
                     /translation="MYKTDISIDFDKINKKIENLELTISEGRVKKIIGLTVEVEGIKA
                     FVGELCVIYNQVNKPVNCEVVGFKDKEVILMALGELTLIAPGCKVISKGIPLSVMCSD
                     NLLGKVLDGLGNPIDNSDAVLGDRYNLNNEPPDPMKRKKIRNIMETGVRAIDAFTTCG
                     EGQRIGIFAGSGVGKSTTLGMIARNAKADVNVIALIGERGREVLDFIDKDLGEEGMKK
                     SVVVCATSDKAPLVRLKGALTATAIAEYFRDQGKKVILMMDSVTRFAMAQREVGVAIG
                     EPPAQKGYTPSVFAMLPKLMERTGTSDKGSITAFYTVLVDGDDFNEPIADTTRGILDG
                     HIVLSRDLANKNHYPSIDVLNSLSRLMNEIASKEDIKIASFARDMLAEYREAEDLINI
                     GAYASGTNKKIDEAIYYHEHIINFLKQGINEKSSFNETISSLRRVFE"
     gene            80325..80771
                     /gene="fliJ"
                     /locus_tag="KR294_000320"
     CDS             80325..80771
                     /gene="fliJ"
                     /locus_tag="KR294_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012815984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export protein FliJ"
                     /protein_id="HBH0238437.1"
                     /translation="MELDKNFKFRLQKVLDLKVKDEEEIKMEFAKIQQKKIDIETNLE
                     NLESNYSKYSISKNNDSIQNQKITINYLLALNNSIMDLSEELDKSTNELEKARKQLIS
                     KQIERKSLEKLKEKKYGQYYKEENLKEQNTNDEFASMSYLRNRQVL"
     gene            80800..82005
                     /locus_tag="KR294_000321"
     CDS             80800..82005
                     /locus_tag="KR294_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-length control protein FliK"
                     /protein_id="HBH0238438.1"
                     /translation="MKIQADSYNIIKDIGDRKSSSKNKNIKNNKFEDNLYKATDHKKV
                     KDRREVSKQNISSDKPENSDNECHLDEDKSNHLEDENTYEKDCSKNNEALQQLLNLLK
                     DNYKKDKDINTILNNIEKLSISDELKQELKLNKNILNKIANQNSELNKANINNSNDIE
                     NLDIVKLRELLEDNANKDIEVITKTTENDTKNIDLYSFDSNRMDNLNSNKQKDDSSDI
                     LEKLAGVNGNKSGNFGQVINKNVDMNKIKNDNVNLKQIESNVMDDSIKAIKHMKTNDI
                     QELTIKLRPKELGDMNIQLLKDGESMRAVVTVFNKDVFDSINKNIADLKQHLELTNVN
                     IKDVSVQMHSDNTNTSDTFDKAFEQQNRQNNQENMSKKNTNDKHNNVVIEDDIKENTI
                     DDDRVDLLA"
     gene            82023..82631
                     /locus_tag="KR294_000322"
     CDS             82023..82631
                     /locus_tag="KR294_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlgD"
                     /protein_id="HBH0238439.1"
                     /translation="MYGIATALAGTQGNYRSNSLSQLERNINDIANKQVRSKGNQTVT
                     DNGTPIIGQGDDADKDLFMKILVAQMGNQDPMNPQDPTEYVSQLAQFATLEKMSAMNE
                     KLDVLLALSNSTLINSALSMATSLIGKEVEVSGEEKEDENIVGVVKSTYIKDGEVHLE
                     LEVDGSDKTVGVKYEKLLKIGEVDENSGEENDSSEHESPEEA"
     gene            82658..83641
                     /locus_tag="KR294_000323"
     CDS             82658..83641
                     /locus_tag="KR294_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-basal body complex protein"
                     /protein_id="HBH0238440.1"
                     /translation="MIKAMYSGVSGMKANQTKLDVIGNNVANAGTTSFKKSSARITDS
                     FYQTVLYASAPTAALGGTNLGQVGVGSKISSINKDMVQGNVQPTNRPSDLMIDGDGYL
                     PVVRQGTVMYTRDGSFNLDTGFKAADGALKNIKGGRLVNGDGYMLQGMIYDGEYKADT
                     GEFVKKGDAKGKEPIVIPLQSISPKDGTVQNVLEYNISKDGTVEFLLSDGQRTQFVYD
                     IPDGAKVGDTPAGIDKLKGTIQKVQTYAFQNPAGLDAEGGNLFKPSANSGDPQIAGAT
                     GTIIQGAIEASNVDIAEEFTEMIIASRSFQANSKIISTSDEILQEIINLKR"
     gene            83654..83857
                     /locus_tag="KR294_000324"
     CDS             83654..83857
                     /locus_tag="KR294_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar FlbD family protein"
                     /protein_id="HBH0238441.1"
                     /translation="MIRVTDLNGRKYILNSDLIVRIDSVPESRILLTTGEKNLVKESV
                     DEIVDKVIKYKRKINVGYIRSEK"
     gene            83857..84675
                     /locus_tag="KR294_000325"
     CDS             83857..84675
                     /locus_tag="KR294_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MotA/TolQ/ExbB proton channel family protein"
                     /protein_id="HBH0238442.1"
                     /translation="MKKTDSLTFIGLIVSTVLVLVGAAKGSSSGLKNFFDVSSILITV
                     LGSFGALMITFTIDDIKLIKNALQYSFKTMSVSKLDLLEQFKTLSKKARKEGLLSIES
                     DVMGIEDPFMKKGLELCIDGLEINEIRSILELEIDSVEDTNNRYSKLFKTWGTFAPAF
                     GMLGTLIGLIQMLADLTSPDLIASGMGKALITTFYGSLLANIALNPIAYNIDEKTEKE
                     IYVKEMMLEGIISIQSGESSIVVEERLATYLSNNEKLEIMKSNKNTERAMSNGA"
     gene            84665..85360
                     /locus_tag="KR294_000326"
     CDS             84665..85360
                     /locus_tag="KR294_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HBH0238443.1"
                     /translation="MARKKNKKKDEINPDAWLATYADTITLILTFFVLLYATSVVDME
                     KFKNIADALKGQFSGTSIFSTGSSTSEKSPIDSVLVDKNDKSNLEQDLKDKVNNSNLQ
                     NSVTVKDDSRGILLELDDSILFDSGISELKVDSKATLNKVYDMIKMMKNKIVIEGHTD
                     NVPVKSSTHESNWDLSSSRAVSVVRYFVEEKGMDPRLFSATGCGEYQPLVSNETAKGR
                     AENRRVNILITID"
     gene            85372..85815
                     /locus_tag="KR294_000327"
     CDS             85372..85815
                     /locus_tag="KR294_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body-associated FliL family
                     protein"
                     /protein_id="HBH0238444.1"
                     /translation="MFKNKKIIIIILILIIFSAGAGFFILGEGGNKQVDKIADLFIPT
                     GKGKDEVKTENLDLEEMVLKLADEGVRYLKVSITVSYDSSYKDIEKNTPLIRDNIINC
                     FMAKRADDFTADNLKNIKEEIKNTLNIQLGENVIQNIYFTNIVVQ"
     gene            85830..86204
                     /locus_tag="KR294_000328"
     CDS             85830..86204
                     /locus_tag="KR294_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FliZ"
                     /protein_id="HBH0238445.1"
                     /translation="MILYLLKILICIPIILILIVLSLKISQGTLLKKYNDKYVKILDI
                     VNISKNNSIIILKIGEEGCIMASSSSSMSKIKDLTKEEILKIENDIKERNFKIQDFKM
                     ERIKKKYDFSRYIGKFTKKEDK"
     gene            86205..86870
                     /gene="fliP"
                     /locus_tag="KR294_000329"
     CDS             86205..86870
                     /gene="fliP"
                     /locus_tag="KR294_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425215.1"
                     /note="The bacterial flagellar biogenesis protein FliP
                     forms a type III secretion system (T3SS)-type pore
                     required for flagellar assembly; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar type III secretion system pore protein
                     FliP"
                     /protein_id="HBH0238446.1"
                     /translation="MELLSKLPLADVPYTSSMQLFLFLTALMFLPFVMFMMTSFVRIV
                     ISLSFLKSALGAQQAIPSQILVGLAIVLTIFIMRPVLNEINEKALQPYMKEEVTMEEA
                     MKEAEGPIKEFLLTQTRQTDLDLFVEQAGLKEKKLTRENIPLSVVVPAFAISELKTAF
                     QIGFLIYIPFLIIDLVVASVLMSMGMFMLPPVMISLPFKLLLFVMVDGWNLIVKTLIL
                     GFG"
     gene            86883..87152
                     /gene="fliQ"
                     /locus_tag="KR294_000330"
     CDS             86883..87152
                     /gene="fliQ"
                     /locus_tag="KR294_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FliQ"
                     /protein_id="HBH0238447.1"
                     /translation="MSEFMIMSVLKNGMFTGAMIAAPVLIVSLVVGLLISVFQATTQI
                     QEQTLTFVPKLIAILLVVAIGGSWMLHTLISFTSEIFNMISLITK"
     gene            87164..88978
                     /locus_tag="KR294_000331"
     CDS             87164..88978
                     /locus_tag="KR294_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fused FliR family export protein/FlhB family
                     type III secretion system protein"
                     /protein_id="HBH0238448.1"
                     /translation="MIFVFIRIVAFFGTLRILFPAGTPALFKSLFAIIISILISSTMQ
                     IEYATNIDNIVLFTLYGVNETITGIMLGYITNLCFYSIRMAGSMMDQQMGLSMINMFD
                     PNSMTQTTLIDNLMNWTALMIFFSMDGHHVLIRGIRYSFELIPIGKPFVDNNIDYIIN
                     IFVQCFLTGFKIAIPIVLCLLMADFILGLISRSVPQLNVMIVGMPLKILVGIALFIIS
                     IPLIVNQISHLLSQIPKMYEGTFALAPMFFMGSADKTEEATPKKKGEQRKKGNIAKSR
                     ELPVAMTLLAFTLLVPTLFSYVVDTLKSSLNYFLSLDFYMNINYSNLEKLVIAGLMDF
                     FKIFLPIAIPFLVLGIIANLFQVGILFTGETLKPNLSKLNPISGFKNMFSMRSLSTLI
                     KDTAIISILAYIGYTFFQDNYLDILKLGNIYLPTLMYTVKDLVYSILSKICVAMIAIA
                     VADYVYQRYSHKKQLRMTKQEVKDEYKNSEGDPEVKAKIKQKQRQISSQRTMQAVPSA
                     TVIVTNPTHLSIAVRYEKGKDQAPVVVAKGADYLAFKIREIAKGNNIPIIENKPIARL
                     LYKQVEIDQEIPEDMYQAFAEILVAVYKIKNRYKVPKR"
     gene            88987..91062
                     /gene="flhA"
                     /locus_tag="KR294_000332"
     CDS             88987..91062
                     /gene="flhA"
                     /locus_tag="KR294_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlhA"
                     /protein_id="HBH0238449.1"
                     /translation="MNKFNLKENMDVIVAFGVVGIVLMMIVPLPTFILDILLAINISL
                     SVLILLMTLFTTNVLDLSIFPTVLLVTTLFRLGLNLSSTRLILTQGYAGEVIEAFGSF
                     VVGGNYVVGIIIFLIILIVQFVVITNGSGRVSEVTARFTLDAMPGKQMSIDADLNAGV
                     IDDKTARKRRKELQQEADFYGSMDGANKFVKGDAIAGLIVTAINIIGGIVIGAVMLNM
                     TLMGAAQTYVRLTIGDGLVSQIPALLISTSAGIIVTRASTDENFGDLVGKQLTAIPKA
                     VMMTGCVLIVLGMMPGLPKPAFFSLGIGAIAAGYFLGREKKDTLEDLEFEKPDMVNPD
                     KNEVEDVTNLINVESIEVEIGYGLISLADESAGGDLLQRIASIRRQCAIDMGIVVQPI
                     RIRDNLQLNPNQYNIKIKGNVVGGYEIMPNMVLCMDPMNQGFSIFGIKTIEPTFGIEA
                     LWIESDKVEDAELKGYTVVDSSTILITHLLDIIKSNAHELLGRQEVKTIIDAARENYS
                     AVVDELIPDLMTLGEIQKVLKNLLREKVNIKDRVTILETLADQSRNTKDIELLTEYVR
                     IALARSICNNLVDDDKTIVVATLSPETEELVSNNLQRSVNGTYPAVDPENTNKIFESI
                     QEVMSNVYFNHNIPVIVVSPKIRAPFRKLVEIVYPNLTVLSLNEIPNDIKIKAEGVVS
                     IYDDEKVYS"
     gene            91037..92053
                     /gene="flhF"
                     /locus_tag="KR294_000333"
     CDS             91037..92053
                     /gene="flhF"
                     /locus_tag="KR294_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlhF"
                     /protein_id="HBH0238450.1"
                     /translation="MMTKKYTANTIQDAMNLAKMELGDNITLIDKKEVRKSGIQGIFS
                     KKDIELTIGWEKRENVEQKDLKREIEQLKSIINNMGFDNKNDNDIDKICKNLLSLELN
                     EEIVESIRIDLQEMKFNGIDTSKNLVEILKKKIKIENQVINGKIALVGPPGVGKTTTI
                     AKLAAKLVFEENKKVGVITIDTYRIGAVEQLKIYTDIMNIPFKGVISPDEMELALDEM
                     KDCDVVLIDTTGRGYKNSMQILEIKNLIDKAETDNIHLVLNCTTRESDTKAIIDSYRN
                     VNFKSLIITKLDETITYGSIFNIMNYAQKPISYITTGQNVPDDIIKPNEDKIIRLLLG
                     VESI"
     gene            92050..92928
                     /locus_tag="KR294_000334"
     CDS             92050..92928
                     /locus_tag="KR294_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MinD/ParA family protein"
                     /protein_id="HBH0238451.1"
                     /translation="MIDQAQILRKIAMEKRGLDEFIVENENVPKIITIASGKGGVGKS
                     NLATNLSICLTKLNKKVLILDADIGMSNIDIIMGVNVKGTIIDVINGEKNIEDIISQT
                     KYGVNIISGGSALNHIEDFTEAQRNKFIHSIEQIHDVDFIIIDTGAGMSKSLLSFIYC
                     STEFFLITTPEPTSLTDAYSLLKAISNFGIKRSANIIINRVIDLEEAKSTYKRIKMVV
                     DKFLNLNLELYGYIIDDKKVSLCVKKQIPFILEYPTSIASKCIIAIAKRMVSQSREDI
                     VDNKSFLRKMFSIFKS"
     gene            92942..93643
                     /locus_tag="KR294_000335"
     CDS             92942..93643
                     /locus_tag="KR294_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliA/WhiG family RNA polymerase sigma factor"
                     /protein_id="HBH0238452.1"
                     /translation="MNREELIKENMPLVKSIARKFFIPGKGFEYQDLVNSGVIGLIDA
                     INKFDAEKGAKFSSYSYIKIKSAILDEIRNQSPISKHNLTKVNKYNRVVEKLQSKLLR
                     EPTSYEIAKELKVSEKELHDIESNIDMLNIVSLNYVIFEDTNETVQDVISDREEEAPE
                     NIIEEEEKLEILSKAISNLNEREKLILSLYYYEDLNLKEIGKVLGVSESRVSQLHRKS
                     IRNLRNKIKELKYSI"
     gene            93659..94081
                     /locus_tag="KR294_000336"
     CDS             93659..94081
                     /locus_tag="KR294_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein"
                     /protein_id="HBH0238453.1"
                     /translation="MIQIILIVVSILIIVTIVINLHKESKNKDNRYFDKIFEQEYEAN
                     DRLIIAEKRRFFLDKVLAEKRINSHIKVYENYNLIKANEERKENIFIESKKEVRQENE
                     LSLKVKHLISSGYDDVEICKMLDIGKGELLLIRSCYKI"
     gene            94066..94251
                     /locus_tag="KR294_000337"
     CDS             94066..94251
                     /locus_tag="KR294_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein"
                     /protein_id="HBH0238454.1"
                     /translation="MLQNIRILLCDKKVFLGIGIGILISTLCIMLFSNNDMSKAEIEK
                     KARALGMKYTSEMKVLE"
     gene            94292..95065
                     /gene="flgG"
                     /locus_tag="KR294_000338"
     CDS             94292..95065
                     /gene="flgG"
                     /locus_tag="KR294_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgG"
                     /protein_id="HBH0238455.1"
                     /translation="MIRGLYTAVSAMITNQQKQNVVVNNLANMDTNGYKSKQLLTKSF
                     DELKLEGYNNYANGTKQKQIIGDISPGISMDETITNFNQGPIKTTDNKMDVAIQGKGF
                     FLVSDAAGNQFYTRNGNFRTDNQGDLITSEGYYVLGTNTATGAVGHINVGNQKFEVAK
                     DNTISLDGNAMYKFNIVDFNNYNNLKKEGDNLYSGGGAMKVNNALTIQSAIESSNVDM
                     VSEINNMMTISREYEANQKIIQAMDSKLAKIASEIGSVR"
     gene            95086..95847
                     /gene="flgG"
                     /locus_tag="KR294_000339"
     CDS             95086..95847
                     /gene="flgG"
                     /locus_tag="KR294_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgG"
                     /protein_id="HBH0238456.1"
                     /translation="MYTMFYTSKTALSANQSKLDIISNNIANSDSTGYKKINMEYSDL
                     VDEVLNRPSYPTNGNDISTGTGAKATAPMRNYEQGALAPTDSKSNLAIDGEGFFRVIR
                     KDGTYAYTRNGGFNVDALGKIVDDNGNILDVQFDAGYNYNNTNIDSTNLTVSRNGELF
                     VDNKKIGKINLYQPIGTQNFISEGDSLFVATDAAQIKQVEKVDIVQGYRERSNVSLQE
                     EFVDLIATQRAFQMNSKGIKTADEMWQIANNLRAK"
     gene            95870..96751
                     /locus_tag="KR294_000340"
     CDS             95870..96751
                     /locus_tag="KR294_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliM/FliN family flagellar motor switch protein"
                     /protein_id="HBH0238457.1"
                     /translation="MNDMKEYDFGKPQSYSRENLTCLNFLLAEFCKKYKNYIIYELKC
                     NSSMVVDSIDQVNYQTFLDRVTSSCVVVQNAMEPVMKNFSFRIDRSVADMWIDITSGG
                     TGVVKDNDRELTELDKKVLLHLMDDLVRNMHLFEGFENIQVLDTHTHINLPQLCSPTA
                     PVCVVDLKVLNDNEYIGSVSLCFPYNGLEALLESISVIEFFDNDVGDDSEEFTQKIYN
                     SVSNIELSVIAEIGKVSINVEDLLKLEVGDVIVTNKKINDYIDIFVENSKSYTATPGF
                     ISSKKGVKINDAVGKEV"
     gene            96754..97128
                     /locus_tag="KR294_000341"
     CDS             96754..97128
                     /locus_tag="KR294_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliM/FliN family flagellar motor switch protein"
                     /protein_id="HBH0238458.1"
                     /translation="MDNSNLISDEEAKMLLNDKVESEVDGDDELALDVSEVNRNNIQR
                     ILDLKLELSVVIGRTKMTLRDILNLHKGSLIELDTLADQDVEILIDNKVLAYGKVVVV
                     DLNFGVKITSIVSEEDMVKSLV"
     gene            97160..98563
                     /locus_tag="KR294_000342"
     CDS             97160..98563
                     /locus_tag="KR294_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBH0238459.1"
                     /translation="MVLILNLNDIKKDILKLNKKDSCSLYNESINNINNNCISTGLKF
                     LKQARDLNPDDVDILNLTGLVNLLKCNFDDAVESFYKSSLCEKTALCEKYINMLTSEE
                     FLIFFEKYNQLIRLINKGMYKEAIQGFKLITDQYCDLIEPYELLALLYDKEEEYIKFD
                     ECLEVLKIIDKENYLLNQENNTLYMYNSANIQTKSNIKVDDYKNEFLHKSSSNHKIND
                     YNDVTKEKSSSKNQKSSDSNKKKSIKKNKYLYIAIILGILLVGQSIYSSYKMNNLTDK
                     ISKNNETKNEESIDSNLTKKENNIEENEDMSKASNINKSNKNINKEDDVKSKKNTVEN
                     EDDKDSDLFTEDELMSKANTLKSEKKTKSSIQLYKKVADIGENKGNTSEATYQVAILS
                     EKLKDYKTAEEYYKMYVENYSEKDAYFDESYYNLGMMYYNNGDLKNSKLTLKKLVNKV
                     PNSMYNNSKVKEILKEE"
     gene            98679..100616
                     /gene="htpG"
                     /locus_tag="KR294_000343"
     CDS             98679..100616
                     /gene="htpG"
                     /locus_tag="KR294_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone HtpG"
                     /protein_id="HBH0238460.1"
                     /translation="MEFEKGSISIHTENIFPIIKKWLYSDKDIFIRELISNGCDAVSK
                     HKRLVSLGEISENKSSDYKITVSVNKGEGTLKFIDNGIGMTEEEIKKYINQVAFSGAE
                     DFFNKYKDKMEESNDIIGHFGLGFYSAFMVSKKVQIDTLSYTEGATPVRWISEGGTEY
                     EISESDARNDRGTTITLFIDDDSKEFLDEFTVRGIINKYCSFLPVEIYLEDVERLERE
                     AKEAEEKAKKQKEDGKEEIVDAKVIEPLNDTNPLWLKSPKDCTDEEYKEFYRKVFNVF
                     DEPLFWIHLNVDYPFNLKGILYFPKLKNEFELTEGKVKLYNNQVFVADNIKEVIPEFL
                     LLLKGVIDCPDLPLNVSRSFLQNDRDVSKISKHIIKKVADKLKSLCKNEREEYNKFWD
                     DIQIFIKYGCLKDESFYEKVKECILFKTIDDEYITLQDYLEKCKDKHENKVFYVSDKE
                     QQSQYIKLFKEYDLSAVVLNSSIDTHFISFMEYKENGVKFNRIDADLSDVLKDKNENK
                     DSEENKEEIAKIEGLFKEAVGERVKNYSVEGLKNEDTPAMVLVSEQSIRMAEMQSRFA
                     GMDLGMNFEEEKTLVINENSPIIKKLVSLKDDEEKKDKITLICNQIADLALLSNKELK
                     PDELDSFVQRSNKLMSLLIEL"
     gene            101003..102133
                     /locus_tag="KR294_000344"
     CDS             101003..102133
                     /locus_tag="KR294_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HBH0238461.1"
                     /translation="MNFNYNLPVNILFGRGRINDVGKEVSKYGKKVLIVTGKNSTKKT
                     GLLDKTIDLLKDSKIEYEVFDRVEQNPLITTIYSGVEIIKSTGCDCVLGLGGGSIMDA
                     AKSIAFSYKNPGDLNDYIFGIRQGEEALPIILVPTTSGTGSEGNCFAVLTNSETKDKK
                     SIKKNSMYAKASIIDPELMVTMPKHIIASVGFDALAHNMEAYLSNGRNPLADVQAIYG
                     IELISENLIKVYNDVNDLEAWEKITLASTIGGMTIGTAGTALPHGMEHPVSGLRDVMH
                     GKGLAALTPTIIESSWDSDIERFGNISKVLGGTCAEDCSDAIRNFLKKIDLDIKLSDL
                     GIEKSDIDWLTDNCMKISVANIKRHPKYFNKEQIKEMYHKSL"
     gene            102360..103382
                     /gene="splB"
                     /locus_tag="KR294_000345"
     CDS             102360..103382
                     /gene="splB"
                     /locus_tag="KR294_000345"
                     /EC_number="4.1.99.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore photoproduct lyase"
                     /protein_id="HBH0238462.1"
                     /translation="MFNPKRIIFEKGTLDTDVGKKIYNKFRDNKDVEIINISSNRIKE
                     HIPGENLYEQYRSGKQTMVVGIRKSLKFQTCKPSANYQLPLVSGCMGRCEYCYLNTQL
                     GDKPFIRVFVNVDEILEQTKKYIEDRKPQVTIFEGAATSDPVPVEPYTNSLKKTIEFF
                     GREEKGRFRFVTKYSDVDSLLDAEHNNHTEIRFSINTPRIINEHEHYTASANKRIESA
                     VKLARAGYQIGFIIAPVFLYEGWKEEYKNLIISIKEALPKDFDKKIIFEVISHRYTTK
                     AKNRILEIYPDTLLPMENEDRKFKYGQFGYGKYVYDKEQLDDMKEFFLKEINGVFKNS
                     LIKYII"
     gene            103564..104475
                     /locus_tag="KR294_000346"
     CDS             103564..104475
                     /locus_tag="KR294_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBH0238463.1"
                     /translation="MHAWESIQITLDLIEANLSEEISINELANKANLSPFYYQRLFKR
                     LVNKTVMEYIKLRRLARASEYLAEHKNRILDVALNFGFASHETFTRSFKKAYGLTPEK
                     YRANPVKLNHFIKPELILNYAMVDEGVPLIADDIVIEVNRKTLSNPRTFVGIEIEVPI
                     CQLVGGETTGIAIVEELWMKLGSQRHNIPNQIPGGNEFAALYMGNAKEGNCMYMAGVE
                     VESGTSVEGYSTFELPAKEYLVCGFEAENFNELVNSAVFKADKFMERWMKKHNLTTTD
                     FAIEMYYPTTPEAAYLEHWIVPVPIEQ"
     gene            104490..104906
                     /locus_tag="KR294_000347"
     CDS             104490..104906
                     /locus_tag="KR294_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3788 domain-containing protein"
                     /protein_id="HBH0238464.1"
                     /translation="MNWQDAFFQDTKPTFEQINEFINNPLWDKLNKTLVSTYNVEPKL
                     EYSKCSMQRGWNVKYKKRGKSLCTLYPQEGYFKALVIVSESNRVEVDLFINTCCDYIK
                     KIYNEVNFFNGSKWLMIQVDSLLVLNDMLELIKFRA"
     gene            complement(105006..105398)
                     /locus_tag="KR294_000348"
     CDS             complement(105006..105398)
                     /locus_tag="KR294_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0238465.1"
                     /translation="MSINTEKNITKNVEELTCPIRYALDIVGGKWKLPIICMLAVENP
                     IRYSSIKRKLDGITNTMLAQSLKDLESTGIVHRKQYNEIPPKVEYTLTSKGKSIVPIL
                     QQFANWGATNMQEKNTCGLSCKECRKIK"
     gene            105539..105934
                     /locus_tag="KR294_000349"
     CDS             105539..105934
                     /locus_tag="KR294_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HBH0238466.1"
                     /translation="MKALEFLNKARVYYLATVDENNQAHVRPLGFVMEYNGKLTFCTS
                     NQKDMFKQLIFNPKVELCCIDQNLNTLRILGEAVFVTSKETQAKALEIMPSLGQMYSV
                     GDGKFEIFSIDKAKVSCCSMSGKKIDVEL"
BASE COUNT        42571 a        11170 c        19080 g        33397 t
ORIGIN      
        1 agggatttaa taatgtttca actataagta ataatattat attgtacact tggattataa
       61 ctgtagtagt gtatttaatt tacactatat ttaaatatat aaaacttaaa aatttaataa
      121 atgacttatc ttatgatgtt gatgatagag agattgtaaa tctttataaa aatatattag
      181 aagaatttaa tataacaaaa gatataaaac tcaaatactc ttatgaagtt gaaacaccag
      241 cattttttaa ttcatgtgta cttttgccac cacatgagta taaattgaaa gagttagact
      301 ggatttttag acatgagctt atgcatttta agagtaggga cctttattta aaatatgtaa
      361 tcctattttt aaaaacagta tattggttta atccatttat atatataatg gataaacata
      421 tagatttaga ttgtgaactt tattgtgatg aaagagtttt aaaaaatcga aattcagagg
      481 aaaaaaagga ttatgcttta acaattctaa atgcaatgag aaaaggttca aatacttcaa
      541 ataaatttat agctggactt cataagcaat ctgatattaa aaagagagtt atgaatatgt
      601 ttaatgaaaa gtacaagaat ggtatattaa tggcattaac tttatgttta ttatcttcta
      661 ttactttttt gaaggttaat tcaactagta ttgttaatct taatgtatta cctaaaggat
      721 ttgaagactt acgaactgtt agcagtatac gtttttcagt tataggattt acatatgcag
      781 atgctcctaa aaatatgagg gaagaatata aaataaattg tgaatcatta ggtttgatac
      841 ctaaagactc tgataaaata gaagttggta tagaatatta tgacagtcta ttgaatgatt
      901 aaataaatat tattttaaca gatattaatt ataaagtttt gaatagtaat ttgttgagaa
      961 ataaatatat ccttataaaa atagatactt atataccaag aataaaaaat agtcaagata
     1021 gtacacaagg atatacttat aaagaactta aataagtgaa ataaattatt aattataagg
     1081 tttataattt taaaaaatta gataaattca ggtgtaaaat actataaaac acaattcgga
     1141 aaagtgtatg ttgaacttca tttaaaatgg aatttcaaag ttgctatagt aagtagttta
     1201 agcattcttc ttatattaat ctttgagaat aatgtattta aaaaagttag taaaaaattt
     1261 aactattgta tattaatgat agttgctatt gatatattat ctaaaaaaat taagtatgaa
     1321 aagattactg ctaggacaat cttttcatac ttaattttta atatttatat tatccaaaat
     1381 tttcatcttt ttaacttaga atttgagaat cactattagg aaataggctt tgatttatgt
     1441 agggttaaaa atttcacaga atatctaact ttatactaaa tccatcaaaa aatatacgcc
     1501 atacaaaagc gcataaaaaa acacataaaa caatatttat gcgcacttta acctcgaatg
     1561 gtacaaaatt ctttactttt acagacccat attatataat taagtaaata atgtatattt
     1621 aggtgacata ttggataagc taatttattt attttattaa tataataata ctataaaagt
     1681 tatataaagt ggtttacaaa aaagttacag atagagcttt tattaatgta ttgtgtatta
     1741 gtattttatc cttaggtaca cttcacctac aaaatagaat cataagataa ttatgggaaa
     1801 attttaggag gtttatcgtg aagaaaaaga tattaatacc agtatttgca tcagttatgg
     1861 cattatcagt aagttcaatt gtaaatgcag atgaagtaaa tgattcatct caaaataagg
     1921 atgataaaac aaatactgaa ttaaatttag gtgaatataa agaagtaaaa tataaagttg
     1981 caaaaataaa agatggagta gctataaaga taagagaaga aggtcaagtt caaaacatag
     2041 cttattctgg agatgaattt acggttttag gaactcaagg agaatgggtt aaggttaaag
     2101 ttgaagatgg cgaaggttgg ttagctacta gatatgtaga tatatctgaa ggtgtaggat
     2161 atactaacgc tgataaagta aacttaagaa aagataagag tgaaagttca gaagtaattg
     2221 aagagctgga aaaaggaagt tctttattgg ttttggaaga taatggagat tggttaaaag
     2281 ttaaagatgg ggaaacagaa ggatatgtaa aatcatctta tatatctgat aaagctcctg
     2341 taatagaaga gccacaagta aacccaagta ttgaccaaaa tgtagattct acaaataata
     2401 atcaacaaaa caatgcaaat actaatcaac aaaataataa ttcaaatgtg ccaacagcta
     2461 actctaatgc agttcaagct gtacttaact tggcatattc taagcaaggt tgtccatatg
     2521 tttggggagc agaaggacca aacacttttg actgttctgg atttacacaa tatgtgtata
     2581 gaaatgcagt aggaaagaat ataccaagaa catctaaagc acaatctaaa tatggacaaa
     2641 ctgtaagtaa agcaaattta caaccaggag atttagtatt cttcacaact aatggttctg
     2701 gttctgttag tcatgttgga atatatgtag gtgggggtaa tatgatacac tcaccatcaa
     2761 caggaaaaac agttagtgta actagtataa attcatcata ctatacagca agatttgtta
     2821 cagcaaaaag aatattataa tcggtttgta atatgacaaa ttgataaata cataaatata
     2881 tataaacgct ctatattata tttaatttaa tcatggaaac aaaataatga ttatatttta
     2941 aatgtactat agagcgtttt tgtatcactt taaatctaat caagattcaa gttaatatga
     3001 ctgttaaata ggagcctttt catatgatga ttatttgtgc aatcccttga caggataggg
     3061 taaaggtggt aagctactaa cagtacaaaa atacttttaa ttttagttca gagaggctaa
     3121 aaaaggagga cgaaagatgt taaaatcaag aaatttaatc caaccagaag acttttcaat
     3181 agaagaaata gatgaaatat tagaattagc tcaaaagata attgacaatc cgtcaaaata
     3241 ttctcgtata tgtgaaggaa aactattagc tacattattt tatgaaccat caacaagaac
     3301 aagattaagc tttgaatctg ctatgaacag attaggagga cgtgtagtag gcttttcaga
     3361 gccaaattca tcctctgcat caaaaggtga aactctagga gatacaatga ggatagtatc
     3421 tggttatgtt gatataatag ctatgagaca tcctcaatca ggtgcagctt cagaagcagc
     3481 tagatatacg gaagtgccat ttataaatgc aggagatggc aaaaaccagc atccaactca
     3541 aacacttaca gacttactta ctataaaatc attaaaagga actttagaaa gccatacaat
     3601 aggattatgt ggtgatttaa aatatggaag aactgtgcat tctttggtta aggctatggc
     3661 aagatataaa aatacaaagt ttgtatttat agcacctgaa gagttaaaaa tgccagatta
     3721 tataaaagaa gctataaagg gacatgcata ttatgaaact aataatttgg atgatgttat
     3781 aggaagcttg gatgttttat atatgactag agttcaacaa gaaagatttg aagataaatc
     3841 agagtatgaa agacttaaaa actattatat tttaaataaa gctaaattag aaaaggcgtc
     3901 taaagatatg ttagtaatgc atccattacc aagagtaaat gagatagaca tagatgtaga
     3961 tagtgatgat agagctgtat attttaaaca agctaaatat ggaatgtatg ttagaatggc
     4021 tttaataata aaacttttag gtataaatga agactaatag ttatcatata atagtaaaac
     4081 aaaggagatt ttgggatgta taaaattctg gaaaatatat atataggcga agatatgtat
     4141 agaatgaaag taaaaggtaa ttttgaaggt aaaatgggac aattctatat gttaagagca
     4201 tgggatactt atccagtact ttcaagacct ataagtatac atgatataga tgaagaaggg
     4261 ataacttttc tttataaagt agtaggagaa ggaactcaaa ttttgagtaa cctaaaggta
     4321 aatgatacta taaaattgga aggcccttat ggtaatggat atgctaaggt tgatggaaag
     4381 gtagctctag taggaggagg aatcggtgta gctccactat atttggttgc taaaaatata
     4441 aaaaattgtg atgcatatct tggctttaga gaagatgtta tattagaaga tgaatataaa
     4501 caagtatgta ataaagtata tacaacagta ggaaatactt ttgtaacaga tataattgat
     4561 gttgagaaat atgattatat attaacatgt ggtccaactc caatgatgga aaaattagtt
     4621 aagatggtag aaggtactaa aacgagaatt atggtatctc ttgaaaacca tatggcttgt
     4681 ggagtaggtg cctgtttagt atgtacgtgt aaaactaatg gaggaaataa aaagacttgt
     4741 aaagatggtc cagtgttctg gggagaggac gtgattttta atgggtaatt taagtgtgaa
     4801 atttggaagt gtagaattta aaaatccagt aataatggcg tctggaactt ttggatttgg
     4861 aaaagaatat aatgagattt atgatataca aaaacttggt ggtataagta gcaagggtct
     4921 tactttaaat aaaaaacctg gtaacaatgg tatgagagtt catgagacac catccggtat
     4981 gatgaatagt gttgggcttg aaaaccctgg agttcaagga tttatagact atgaattacc
     5041 tttttttagt aaactagact tagtcagaat agctaatgtt ggaggtggga cattagaaga
     5101 ctacttatta ggggttcaaa tgttaaatga caagcctata gacattattg aattaaatat
     5161 atcttgccca aatgtcaaag ctggtggaat ggcttttggt ataaaaaatg aagtggcaag
     5221 agaagttgtt cgtgaggtaa gaaacataac gaaactgcct ttagtaataa aattatcacc
     5281 caatgcagaa gatattgtag gaatggcaaa agtttgtgaa gaagaaggtg ctgatggagt
     5341 ttcattagtt aatactttta aagcaatggc aattgatata aaaaatagaa gaccagtatt
     5401 tgaaaatgta tatgctgggt tatctggacc agctataaaa cctatagctt tgagaatggt
     5461 acatgaagtg tgtaaaaatg taaatatacc tgtaatggga atgggcggaa taactaaagc
     5521 cacagatgct atagagttta taatggcagg agctacttgt atccaagttg gaactgcaaa
     5581 ttttatgaat cctagaatag gtattgaaat aatagatgga attaatgaat ttatggatag
     5641 agaaggaata aaaagtttag acgaaataag aggaattata taaggtagaa taaatagtat
     5701 tttaaagata aaaaatatag attaaataaa caataatttt ataacattaa catggaggaa
     5761 aaataatatg agtaaagtag atgtagtgga tatattaaag aaaagtgatg cattgttgga
     5821 gggacatttt ttattatctt caggaaaaca cagtaataga tacgtacaat gtgcaaaagt
     5881 attaagattt ccagaatatg ctgctgaggt attaagtaca gttgttgaac aaataaaaga
     5941 cttagatata gacttagtag taggaccagc tatgggtgga gtaatagttt cttatgagtt
     6001 aggaagacaa ttaggaaaag aagctgtatt tactgagaga aaagacaata caatggagtt
     6061 aagaagagga tttgaagtta aaaaaggagc aaagataata attgctgaag acgttgtaac
     6121 tactggtaaa tcaactatgg agacaaaaag agtattagaa gccttaggtg gagaagttgt
     6181 aggtgttgca tgtatagcag atagaactaa tcatgatata ggtatgccta tatatagtgc
     6241 tataaaactt gatattcaag tttatgaatc tgatgagtgt cctttatgta aggaaggaaa
     6301 attaccagtt gttaagcctg gaagtaggga gttcaaggaa ttagggatgt aataaaaact
     6361 taattattta tagtgttact taaaaaatgt aaatttttta gagtaaaaat ttgtaatata
     6421 acatataact taaaaataaa aagcagttag ccttataaat gaaggttagc tgtttttttt
     6481 gttaaaaata tatttacaaa ataagagata gtagcagtac aatataagta taaggtaaaa
     6541 gtattatata ttagggaggg gtaagtatga aaaatcaatt aaatgaaaat cataaaaagg
     6601 ttgtattttt tggagtaggt gctgtaggag ctacttttgc agaacaattt tttaactcta
     6661 aatatgattt taaaattctt tgtgataatg aaagaaagaa aagatattta gaagaaggat
     6721 ttataataaa tggaaaaagg tatgattttg attatgtaac taaagatgag tataaacaag
     6781 aggctgattt tataattata ggtctaaaat ataataattt aaaagaaaat ataaaagaat
     6841 tagatggatt agttggaaaa aatacagtta taatgtctct gctaaatgga gttgatagcg
     6901 aagagataat aggagaaaga tttggaattg aaaaaatggt atattcatat gttaccaata
     6961 tagatgcaaa gaaaatcaat aataatatta tacacactac taatgggata attgtatttg
     7021 gtaacaaaga taatagtgaa gatagaaaaa ctaatataat aaccgaagtc tttgatgatg
     7081 taaatataga atatacttta tcaaaagata ttcaacgaga tatgtggtgg aagtacatgg
     7141 ttaatattgg tgtaaatcaa acttcagcta tacttggtgc accttatgga gtttttcaga
     7201 gttctgagca tttaagagaa ttagcaaaat ctgcaatgag ggaagttgtt gctatagcac
     7261 aagcaaaaga catatctctt acagaagatg atgtggaaca ttcattacat agaatactag
     7321 aacattcaaa agaaggaaga acatcaatgc ttcaagatgt ggaagctcat agacttacag
     7381 aagtagatat gttttctaag aatatctgca aacttggaaa aaaatataac atacctactc
     7441 ctataaatca gactttcttt tatatgataa aagtaattga aagtagattt taaagggtct
     7501 ttgtaagaaa tattgataat tattgatttt aaattttatt aatgttatat actatttaag
     7561 ttactaaata tttttaactc ttcaatgaaa atagttgctg cttttgataa agttatatct
     7621 tttggaaata tatatgagaa atgtctgttg tagctgcttc caagctctat gacagacagc
     7681 tcattgttta gaacaggtaa gcttgtcact agattagaga ctattgtaat tcctaaatta
     7741 tttctaacag attctttgac agcataatta cttccaaaaa ccatcatact ttttggaata
     7801 atttctttaa cacttaaaaa catatctaaa taatctctgg ttccagaacc atcctccctg
     7861 actatccatt tttggttttg aagtttatca aaactaaaat cttttaataa atgactcttg
     7921 tatggaagtg ctaaaaccat cttatcttca aaaaaatatt cttgaataaa tgaaggggaa
     7981 gagcaagtgc cttcaataag accaatgtct aaaatataat ccttaacatg agaagatacg
     8041 attgatgtat tttttataaa aacttctaca tctatgtcag gatacttttt agaaaataat
     8101 gctagaaaat ttggtaaaat atactctcca atagttaaac ttgcaccaat ctttaagtga
     8161 ccagttatag catctgaaac ttggcttaca tcatgataag taatatttaa aagatttaat
     8221 atttctttag ctcttttgta caagatttgt ccactttctg ttataaaaat ggttttttgt
     8281 ttaatagacc tgtttataag cacaacttta aaataatttt ctagattttt tatgtgttta
     8341 cttacacttg gttgtgatag atttaaatat tccccagctt tagtaaagtt tttgtattca
     8401 acaacagcta caaatgtttt taattcttca aacaattttt tgtctccttt acctaatgaa
     8461 attttacatt ttttatatac tttctacaga taattatact atatataata accattaaaa
     8521 acattaatca ttacgatatt atatatttat tttacttatg gttattacaa ttatatacta
     8581 ttgctatgaa gaaaactata ttaattataa ggtaggtata ttatgttaaa gaaaaaaagc
     8641 agtttgacat taaaaactat aagggaaata ttaccaggac tgtttgtatc agtattagta
     8701 ggttatatta gtatatttat ttctatttta attcctaagg taggggcagc atcaatttct
     8761 atatttttag gtatgtttgt aggaaaccta tttttaaatc aaaaggtatt tcaaaaaggt
     8821 tataaatttt cagagacaga tttgttatca tattcaatag tactattagg agcaacactc
     8881 agtgtatcta ccttaataga cttaaaagtt tcaggaattt tatttataat attgcaaatg
     8941 acaataacaa taatagctgc actttatata ggtaaaaaac taggatttga agaaaacttt
     9001 agatttctaa tggcaagtgg aaatgcagta tgtggttctt ctgcaatagg agcaacagtt
     9061 ccagtggtta atgcgacaga taaagaaaag ggaattgcag taactattgt aaatgttact
     9121 ggtatatttc ttatgttttt acttccaata atatctcaat ttttatatag ccatgaactt
     9181 gtaaaaactt cagcaatgat aggtggaact ttgcaatcaa ttggtcaggt tgtagcaagt
     9241 ggagcaattg ttggagaaaa tgtaaaagat ttagctacta tttttaagat agtaagagta
     9301 atatttctag ttgttgttgt attagtattt ggacatatga aaaatcaatc taatagggaa
     9361 attcttgaag aagaaaagga tgagataaaa aagaaaaaag tgactatacc atggtatgta
     9421 attggattct ttataacttg tgcacttttt tcaatgaaca ttataccaca agaagtatct
     9481 gtgttgtgca aagaaataag taacaaacta gaaataatag ctttagcagc aattggatta
     9541 aaggttaatg taaaagattt agtgaaacaa gggaaagaag tttctttata tggtttattt
     9601 gtaggtatag tacaagttgt atcagctgta gttttaataa aaatatttat atagcataaa
     9661 aatagtattt gtaatattaa tttgattaat taaaataata tgatactaat aatttataat
     9721 ataaataaaa aatgaatttc gataagttta agtgggtata aacttataga aattcatttt
     9781 ttatttaagg taaaaattta aagtaaaata ttattttaca taataataac cttataaatt
     9841 ttgaaattac ttatctttgt gttaaaataa gtaaaatgca catattagag ctaagttttt
     9901 aagtaaataa acaaaatgaa aatataaata ttaaggagat ttggtatatg aatgtttatg
     9961 aaaaaggtaa tggagttata ctagaaggag taacagattt tgacccagta catatatttg
    10021 agtgtggtca atgttttaga tggcacaaac aagaagatgg ctcatacact ggagttgcaa
    10081 aggggagaat attaaatgtc aaaaaagaga atgataaaat atatttaaat aatactaatt
    10141 taaaggagtt taacagcatt tggtataatt actttgattt aggaactgat tatacagaaa
    10201 taaagaataa gctaaaaaat atggatgaat atttaaataa ggctactgaa tttggatggg
    10261 gaataagaat attaagacaa gatggatggg aaatgcttat atcatttata atttcctcta
    10321 ataataggat tcctatgata caaagagcta tagaaaattt atcaagaaaa tttggtaagt
    10381 atataggtga atatgaaggt aatgaatact atgcattccc aacaccagaa gaactaaata
    10441 aggcctcaca agaggaaata agagcatgtc aaacaggttt tagagataag tacataaaaa
    10501 gtactacaca ggcagttata gagaataatg atgaggtatc tgaatataca aatttaagta
    10561 ctgaggattg tagaaaagag cttttaaaat ttaatggagt aggaccaaaa gtatgtgatt
    10621 gtattgcatt atttggtatg caaaaatatg attcttttcc agttgatgtt tgggttaaga
    10681 gagttatgca agaattttat atagatgaag acatgagttt acctaaaatg agaacttatg
    10741 gaatcgataa atttaaagaa atgtctggat ttgctcaaca gtacttattt tactatgcaa
    10801 gagaactcgg tataggaaaa taaattaagg gggagaaatt atgggagtaa taggaacaat
    10861 atttctgttc tatttaatta tatcatatct agctggagcc ataatttctg tgattatatt
    10921 gcttgaaaat agagaccctg caaaaacaat gtcttggcta ttgatgttta ttatatttcc
    10981 aggtgtaggt ttaatgatat atgctatttc aggtagaaat attagaaaaa gaaaattatt
    11041 taagactcaa aaactagcta ataatataaa agaaaagaaa ctatttgata cattagaaaa
    11101 gataacagaa atagttgaat tagaaaaaga atctataaaa caaaataagc ttttaagaga
    11161 tgaagaggat ggtagttata gaaaaagggt aataaatatg ttgttaaaga ctggtatgtt
    11221 tccctttact aaaaataata aagtggatgt atttgtagat ggaaatgaaa agtttaaaag
    11281 acttatagaa gatataagag aagccaaaga ccatattcat ttagagtact ttatcatcaa
    11341 agatagtgaa ataggtaggg tgttaaaaga agaacttata aaaaaggcta aagaaggcat
    11401 taagataaga attttatatg atgatgtagg atgctggaga ttttggttta atagaaaatt
    11461 tttccgagaa atgagggaag taggtataga aattgcagca tttttaccta caaaatttcc
    11521 tataatagga gggaaattaa actatagaaa tcacagaaaa attgttgtta ttgatggaat
    11581 aattggatat acaggtggaa taaatatagg agatgaatat ttaggcaaaa atgataagtt
    11641 tggatattgg agagatactc atattaggat taagggtatt tctgtataca tgcttcaaat
    11701 gacatttctg attgattggt attatacgac aaaagaagta ttagtgacta aaaattattt
    11761 cccaagtgta gggaatgttg gtgaaagtat gatacaagtt gttgcgagtg gtccagacag
    11821 tgactgggaa gatattcatt atgcttattt ttctgcaata tgtcaggcta gaaaaaatgt
    11881 ttatatagaa actccatatt ttattccaga tgaaagtcta ctaaaagcta taaagagtgc
    11941 tgctcttagt ggagttgatg tgagaataat atttcctaaa attgcagacc acaagatagt
    12001 aaatatagca tcttattcat attttgaaga aatattaaga gcaggtggta aagtttattt
    12061 atataataaa ggatttatac attctaaagt cgtaataata gatgataaaa ttgcttctgc
    12121 aggtacagct aatatggatt taagaagttt tatgcttaac tttgaggtaa atgcatttat
    12181 ctatgatgaa gaagttatta gggtaatgac agatgatttc tttgaggatt taagtcactg
    12241 tgaagaactt aatttggagg tatttaagaa tagaaatatc atacaaaaaa tcaaagaatc
    12301 tgtagcaaga ttattttcac caatattata aaaaattatt aaaaaaggta ttgaaaatta
    12361 tgtgtgattg gtatattata ataattgtta gcactctatt agatagagtg ataataaata
    12421 aaaagtatat atataaatct acatatataa gtagtattaa tttaaaaata actaaaaaca
    12481 taggcgaact agtctatact taatatttta ggaggcgtga ataatgaaaa taagaccatt
    12541 agctgacaga gtagtaatta aaaaagtaga agcagaagaa aaaactgcaa gtggaatagt
    12601 tttaccagga gcagctaaag agcaacctca aatagctgaa gttgtagaag ttggaccagg
    12661 tggaatagtt gaagggaaag aaataaaaat ggaattgaca gtgggagata aggttatatt
    12721 ccaaaaatat tctggaacag aagttaagat agaaggacaa gaatacacaa tactaagaca
    12781 gagtgatgta ttagctgtta ttgaataaat atagaataaa tttattagga ggggtttaaa
    12841 atggctaaag aaattaaatt ttcagaggaa acaagaagag ctttagaagc tggtgtaaat
    12901 aaattagcag atacagtaaa agtaacatta ggacctaaag gaagaaatgt tatattagat
    12961 aaaaaatttg gttctccact tataactaat gatggagtaa ctatagcaaa agagatagaa
    13021 ctagaagata gatttgaaaa tatgggtgct caattagtta aagaagtagc aactaaaact
    13081 aatgatgtag ctggagatgg tactacaact gctacagttt tagcacaagc tataataaga
    13141 gaaggtttaa agaatgtaac agcaggggct aacccaatac ttttaagaaa aggaatacaa
    13201 aaagcagtaa cagtagcagt agaagaatta aaaaatcaat caagaatagt agaaacacaa
    13261 gaggctatat ctcaagttgc ttctatatct gctggtgatg aagaagttgg aaaattaata
    13321 gcagaagcta tggaaatagt aggtaaagat ggagttataa ctgttgaaga gtctcaaact
    13381 atgaatactg aattagatgc tgttgaaggt atgcagtttg atagaggatt tgtttctgca
    13441 tatatggtta cagatgtaga taaaatggaa gcagttttaa atgacccata tatattaatt
    13501 actgataaaa aaatatctaa catacaagaa ttattaccag ttcttgaaca aatagttcaa
    13561 caaggtaaaa agttattgat aatagctgaa gatgtagaag gtgaagcatt atctacatta
    13621 gtagtaaata aattaagagg aacatttgat gtagtagcag ttaaagctcc aggctttgga
    13681 gatagaagaa aagaaatgct tcaagatata gcaatactta caggtgctca agtaatatca
    13741 gaagaattag gttatgattt aaaagaagct gatttatcta tgctaggtag agcttcatct
    13801 gttaaggtaa ctaaagaaag tactacaata gtagatggtt ctggagataa aaaagctata
    13861 gaagatagag taactcaaat taaacatcaa gtagagcaaa ctacttcaga ttttgataga
    13921 gagaaattaa tggaaagatt agctaaactt gctggaggag tagctgttgt aaaagttgga
    13981 gctgctacag aagtagagtt aaaagaaaga aagttaagaa tagaagatgc tcttaatgca
    14041 actagagcag ctgtagaaga aggaatagta gctggtggag gaactgcttt tgttagtgtt
    14101 ataccagcaa taggaacact aattgagagt ttagaaggag aagttaaact aggtgctcaa
    14161 atagttaaaa aagcgttaga agagccatta agacaaatag ctataaatgc tggtcttgaa
    14221 ggtgctgtaa ttgtgcaaaa tgttgttaat tctgaagcag aaactggatt tgacgcattg
    14281 aatgaaaaat atgtaaatat gatagaagct ggtatagttg acccaactaa agttagtaga
    14341 agtgctttac aaaatgctgc atcaatagca agtactttct taactactga agctgctgtt
    14401 gctgaccttc ctgaaaaaga agatgtagga atgccaggaa tgggtggcgg aatgcctggt
    14461 atgatgtaat ttaaaaaatt taaaatataa attttaatat aaagaactat ttcgacttag
    14521 attttaaact ctaagttgaa atagttcttt tgtatatatc taatttttgt atatctataa
    14581 attcaataca catatttaga taatcagtat ctagtttgta ataatatttt agagtagtat
    14641 tgttattttt taggttatga ttttagatat atattaatta aggtataatt gttgatagag
    14701 aataaatcaa atttaaaagg atgcgataat atggacttaa gaaaattgct tgaagaagtt
    14761 aaaaatgaaa atattgatat agattttgcg ttagaaaagt taaaagattt accttatgaa
    14821 gaccttggat atgcaaatat agaccatcat agagaattaa gaaatgggta tccggaagtt
    14881 atttattgtg aaggtaagag tgatgagcat attttaggga ttattgataa aatgaatcaa
    14941 aaaagttcta acatattggg gacaaggtgc agaaaagaaa cttttctgaa aattaaagaa
    15001 atctataatc atgctgagta cgaagaggcg tctaaaattc ttaagattca aaatcatgat
    15061 atagagaata taggaaaagg taaaattgtg attgctacag ggggaacttc tgatatacca
    15121 gtagcagacg aagcttatca tacagctaag tttttaggta atgatgttga tagaatatat
    15181 gatgttggag tggcaggtat acataggctt ttaaataaaa gacataaaat agatagtgct
    15241 agagtaatag tagccgttgc aggtatggaa ggtgctcttg caagtgtaat tggtggactg
    15301 gttgatgttc cagtaatagc tgttccaact tctgttggat atggagcaaa ttttggagga
    15361 ttagcagcat tactagctat gttaaatagc tgtgcatctg gaatatctgt tgtaaatatt
    15421 gataatggat ttggagcagg atatttagca tcaatgataa ataaactgta aatacattga
    15481 tataaattaa acaaaactat ataataaaat ttaatttcta ttatattttt actattaaaa
    15541 ttgaggagac atatatgagt gaaaaaatac tttattttga tataataagc ggtatatcag
    15601 gggatatgac ccttgcaagt ttattaaatt taggtgtgcc taaggaaatt tttttggagg
    15661 aaattcataa actaagaatg agcgatgaat ttaatataaa catcagctcg aaaactgaaa
    15721 atggaatagt aggtacaaaa gtagaagtaa ttacaaaaga aaaacataca catagaaatt
    15781 tagtggatat atttgaggtt atagataaaa gcactctaaa cgaaaatgta aaatctaaag
    15841 caaaaaaaat atttatggta attggagaag cagaagcaaa agttcatgga actacaatag
    15901 acaagataca ttttcatgag gtaggggcta tagattcaat tgtagatata gtaggagctt
    15961 ctatattagt tgacttactt tgtgtagata aagtttgtgc tagtacagtg tctgttggtt
    16021 caggatttgt aaaatgtgaa catggaatta tacctatacc tgcacctgca actatagaaa
    16081 ttttaaaagg tgtgccaatt aaattaaata atgtaaatgg agaatgtaca actccaacag
    16141 gagctgcaat cataaaagtc ttgtgtgatg agtttgtaga tgagcttgaa ttttctccaa
    16201 agcaaattgg atatggtata ggtcataaga agtttgaagt accaaatata ctcagaactg
    16261 tattaggtga aaaaaaaaag aagaattaat ttatgaaatt agtgcaaaca ttgatgatat
    16321 gtcttcagaa atctattctt atttgtatga aaaaatatta gatgagaaag cattagatat
    16381 ttatacagag agcatttata tgaagaagaa tagaccagca acaaaagtat caattttatg
    16441 taatgaatca gatttagaaa aatttattaa aatattactt ttagaaacta gtacttttgg
    16501 agtgagatat aatgcatata atagagaaat tctagagaga aaatttgtaa aattagatac
    16561 aaaatatgga gtggttacag taaaactagg gtattataaa ggaaaactag tcaaggctac
    16621 tccagaatat aatgaatgta aaactatagc aaaaaatgaa gatattccta taaaaaaagt
    16681 gtttgctgat ataaatttta gaataaaaga agaatttagt gaaaacttat tgacataagt
    16741 aataaatttt gataaattaa tattcagcct tattaaataa aagtaaacag aaaaaaatat
    16801 ataaaatata aactcactcg tatatgctca gaaatatggt ctgagagtct ctaccaagat
    16861 accgtaaata tcttgactat gagtgaaatt attataccaa aagacctagt taagtaaatg
    16921 tgtaggctga gttaaactcc ctatgtgttg gctataagat aaaggtattt tggaagcctg
    16981 tatagtaatt tcacttttgc tagaaattat ggaagttact atacaggttt tttgtgtaaa
    17041 aagatttaat ataatttaga ctgtattgtg ttaaaataaa tatataaaaa ctatattata
    17101 caaggagaga tgtaaattta tgaaacatga attagtactt gtaatagatt ttggaggaca
    17161 atataatcag ttgatagcta gaagagttag agaaaacaac gtatattgtg aaatacttcc
    17221 atgtactgca agcatagaaa gaataaaaga aaaaaatcct aaagggataa tatttacagg
    17281 cggtccaaat agtgcgtatt tagaagattc tccaacaata tcaaaagaaa tatttgaact
    17341 aggagtacca atacttggaa tatgctatgg tattcaaata atgtctcatg tattgggtgg
    17401 agttgtaaga aaaggtaata aacaagaaaa agaatatgga aaaacagcta taacttatgg
    17461 aaaatcatca ttatttgaag gaataactac aaatagtgta tggatgagtc atacagattt
    17521 aatagaaaaa gttccagaag gatttactat agttgcaaat actaatgatt gtccagtagc
    17581 agctatggaa aatgtagaac gaaacctata tggagttcaa ttccatccag aggtagaaca
    17641 ctgtttggaa ggggacaaga tacttacaaa cttcttatat aatatttgta aagtaaaagg
    17701 tgactggact acagattcat tcatagaaga taaaataaaa gaattaaaag aaaaaatagg
    17761 cgataaaaaa gctttatgtg ctttaagtgg aggagttgat tcttctgttg ctgcagttct
    17821 tattcataaa gcaattgggg acaacttaac ttgtatattt gttgaccatg gtttacttag
    17881 aaaaaatgaa ggaaatgatg tagaaagaat atttagagag aaatttgata taaatttaat
    17941 aagagttaat gcagaagata gattcttatc taaattaaaa ggagtttctg aaccagaagc
    18001 taagagaaaa ataataggtg aagaatttat aagagtattt gaagaagaat caaataaatt
    18061 aggaaaaatg gatttcttag tacaaggaac aatctatcca gatgttatag aaagtggaca
    18121 tggaaatgct gctactataa agtctcatca taatgttggt ggaatcccag aagatgtaga
    18181 cttccaagaa attgtagaac cattaagaga gttatttaag gatgaagtta gaaaaatagg
    18241 attagagctt ggtatagaag aaggattaat atttagacat cctttcccag gaccaggtct
    18301 aggaataaga gttataggtg atgtaactaa agaaaaatgt gatatattaa gagaagctga
    18361 tgctgtttat atggacgagc ttagaaaagc aggtttatac agagaaatat ggcaagcttt
    18421 tgcaacatta ccagatgtta agactgttgg agttatgggt gatgaaagaa catatgctta
    18481 tttagttggt ttaagagcag ttacttcttc tgatggaatg acttctgact ggtataagat
    18541 gccttatgat gtattagaaa gaatttctaa tagaataata aatgaagttg atggagtaaa
    18601 tagagtagtt tatgatataa cttctaaacc tcctggaact attgaatggg aataaaatat
    18661 agaatgccaa aaatccacat aaatacagga tttgaggtct ctcttacttc tatgttatac
    18721 tggtttgata ctatcaatat ttgccagtat cttatggatt aataagcaaa aaacatcctg
    18781 ctgaatgata aattcagcgg ggtgttttta ttttgtttta gaactccttt gctctgaaac
    18841 tcgaagtatt taacactgat gattttgtta tcttttagtt ccttttgtgt catgctctga
    18901 aagacaaatt gatacaataa aaaagtaatt tcttaatcat tgatggagat atgtgtttat
    18961 gttactcttg atggtaattt gagtaatatt gttcatagct ttttatattc acttaattag
    19021 aaaaccattt ggtataatca taaataaact tgatgatata atagaaaaga tttataatta
    19081 ttagaagtat ataaaagtat tttatgtcta tgaaatgtat gtctataaaa catatagatg
    19141 acttttgtat attaatgtat gaatattgat attatagaag aattgagttg tcaatgatac
    19201 taaatcaaat atttatagaa gctggaggga ttatgagaaa taaaataatt ataggaatta
    19261 ctttttcact tgtattacta atgtctggat gtgcttcaaa acaaaccgca gaaataaacg
    19321 tattagcaac tactgattta catggagtta taccttatga gttaacttct tatgtaaaag
    19381 aagaaagaaa aaaagataaa aatctaactt tagtagatgc aggagatttt tttgatagtg
    19441 gagaagtgtt tggttctagc atggatagtt attttagtgc tagatataaa gatggtgata
    19501 ataacactga aagttatatt gagacgccta tttcaaaaga tatgaaagag gtaggttatg
    19561 atgttgcagt tcttgggaat catgaattta tatccaacaa taaattttat ctagataata
    19621 tgatatctga ttttgagaag caaaaaataa atattttatc ggcaaatacg tataaaaaaa
    19681 atggagatag ttatacaaaa ccatacataa taaaaaatat taatacacct gaaggaaacg
    19741 taaaactagg aattttaggg cttactataa aagaagttgg tgagaggaaa cagtggaaag
    19801 atggaaaact tgttgactct aagtctttag aactaaaaga ccaagagggt tacaatggtg
    19861 aattgtatat gaatgattta gtagaagatg ctaaaaagtg ggttggtata atggaaaaag
    19921 agaagcctga cattatagtt gctgtggcac atacaggtga gaaacctaag aaacctaaaa
    19981 acccaggaaa tagaatacaa gacttagctc aacaagttga tggaattgat gctatagttg
    20041 caggtcataa tcatgttcaa attgagcaac atgattataa aaataaatca ggagaaaatg
    20101 ttatagttac tgagccagga aagcatgggg aatgtatttc taagattaat tttaaattag
    20161 aaaaaaacaa tgataaatgg aatatagttg acaaatctag taaattaatt aaatttgaaa
    20221 aaaatcaaga aagtgataaa tttggagaat ttatttcttc aattaataaa gtaagtaaag
    20281 ataagaaaga aataagatta tcagaagtaa agactcctga atgggataaa atatatgttt
    20341 ttaaatctgg aacatctgca gatgatatat ataaaacaat aggatataaa tggagaaata
    20401 tatcatctcc aaagggtgat gacatggtgc agattgttgt aatgaataat aataagcctg
    20461 ttagctatgt atatggtgaa gctgaagtta tgccaattaa tataaaatgt gatgaatcag
    20521 agtataaaga taatgttgta actatttatc ctaataaaaa tgataaattt aaaattgaaa
    20581 aaggtaaaca agaatatagt attaatttaa aacatataca atagaaactt ttatcttatt
    20641 taagtttaga ttgtacttaa aataaagtgt gtattatttt aaaaattgat gataattaaa
    20701 atcacaacat taaagaatag tacacacttt ttatgctaaa aaatagaatg ttaaaaaatt
    20761 aaacctttaa attaaagtac attgcttata ttatccaata ttattttcaa aggttgtgta
    20821 atatttttat ccttatgtaa tattgctaac attttatttt ccatatctat cccatctaat
    20881 tcaatcaatc gcaatttttt atgtaagagt gaatctaata ataaattttc tggcaaaatg
    20941 gttataccta accctgcttg tgcagcttta ataagtgcaa aagaattaac actttcccaa
    21001 acaggataag ctttttggtt tgaaagagat aatacactgt ccaaagtatt gcgaatggca
    21061 cttccttgct cacgtaacaa taacggaaac gtgcataact gtcgtagaga taaggcttgt
    21121 ttagtattgg tggtggttat gcaatcatac ttttaatcca agagaaagta gtaaatcaaa
    21181 ctggatggat aagtgagaaa atgtttacag atattataac tatttcacaa atgacaccag
    21241 ggccactggc tgttaatact tctacttttg ttggacttca aattggaggg ttttggggag
    21301 cagttgcagc cactttaggt tgtgtattat gtggtgtagt aatatctcta tttttatata
    21361 atttttttca aaagcatcag aactctactt atatatttga aatattaaat ggtctaaaat
    21421 cagcttcatt aggtttaatt atctcagctg cggctacaat tataatcctt gcattatttg
    21481 ggacgaataa agtgtacttc aattctatat ttgagatgct aaactggact gcactaataa
    21541 tcttttttgt tacactactg atagtacgta agtggaaaat taatcctatt gtgattataa
    21601 taataagtgg tatactggga atattttttt atttataagt ttttggtaag tagaggatat
    21661 ctattttttt atatcttaaa tccaaatagc caataaagta aggccatttg gatttttaat
    21721 aaattctgaa aagataatca gaaacccata taacatttaa attatatcac tggttttcta
    21781 caaaccaatc ataagcttct tggcaaaatt tctcactatc tatatagtaa ctattatgaa
    21841 cattattaat ttcaacaagt ttctttttac attttagtga attataatag ctatcaaaat
    21901 attgggtttt aaaatatcta tcatgaagtg ttttaaagac aagagtaggt atgttgactc
    21961 catcttttat cttactatct tttgcaataa agcattctaa cattgtatta attatctttg
    22021 tactattttt ccaaatatga ggatttttct tttcaaatat tttataaaat tcattatcat
    22081 agacttcatt ataaccttta tatttaggtg gttttactgt tatgtgaaaa ttaggaagaa
    22141 acttaaagaa aaagtttaat aatttaacag tgagataggt atagcctact cctgttgtgt
    22201 ttttataatc aacacaagca aactgagcaa aactttttaa cttattgtct gaacatgcat
    22261 aatattgtgc aaacatacca ccaattcccg tattcccata tagatgtatg ttggaagaat
    22321 aatttttttc tatgtatgta atgacagaat ctaagtcttt tacaattgaa ttgcgagaaa
    22381 aatctttttc atatccatca cttttccctg ttcctgaaaa atcaaaagca aatatattta
    22441 cattatgttt ggcaagtggt tcatatgctt tttgcatctc aagcgtagtg acaataggag
    22501 tatgtgtaac aacaatattc atggatgatt ttctggtaat aaatgagtta caaaaaatca
    22561 ttgtatctcc atttggtatt tttatatgtt tccaactcat ttgattttcc tttctctatt
    22621 ataaaatata ataattttta tgttctgttt tatatattat tcatatttta tcacagataa
    22681 tatactaaag ttaatttttt tattgtacac ctattataat aattcttcta taatataaga
    22741 cattctataa ttttatattt aagttcatgt gtatttaatt gtttttatat aaaatgtcca
    22801 gtaatactat ttggatttat ttttatttca tcaggagttc cagaagcaac aatttcccct
    22861 ccatttattc cactgtctgg acctatatcg ataatccaat cagaagcacg tataacctct
    22921 gtattgtgtt caataattaa aagtgaatgc tgttcattta caagttttct aaaagtaatt
    22981 aacaaatttt ctatatcttt aaaatgaagt ccagtagtag gctcatccaa tatgtacagc
    23041 attcgttttt tagtttttgt ccctaattct tttgctaatt ttatcctttg agattctcct
    23101 ccacttaatc ctaatgtatt ttgtccaagc tttagatatc caagtcccac ttcatctaat
    23161 aaggagagtt ttctatatat atcagagcaa tcgctaaaaa atgtttttgc ttctgctact
    23221 tccatgtcaa gtatatctgc aattgtcttt cccttgtatt gtatagacag tatttctttt
    23281 tgatatctct taccttgaca ttcactacaa gttacccatt ggtctgccat atattgcaga
    23341 ataatttttg ttttacctaa tccttgacag tttgggcatt gccccttttt gctattaaag
    23401 ctaaaatagc tttcatccaa taatttttgt tttgcttgtg gagtttcagc aaatagagaa
    23461 cgaatttcat caaaaatatt gatatatgta gcaggtgtag aacggctaga ttttccaata
    23521 ggtgtttggt ccattaagat aaaatcatca atagcatcaa atccagtaaa ttcagtataa
    23581 tttttatctg ggatagattt ttgtttcaat ttttcttcta gagcaggaag taaactgtga
    23641 aatacaagag agctcttacc agaaccacta acacctgtaa tagagcacat acagtttaag
    23701 ggaatttcta catcaatatt ttttaagtta tttgcatggc atccttttaa gcttaaccat
    23761 ttacttggta taattttatt ttgtgaactt attttattgt atgtgcttaa atatttacct
    23821 gttatagagt ttggattttt tataatttct tgggttgtac cttctgcaat aatgaacccc
    23881 ccttttgtac cagcacttgg gcctacatca ataatataat cagcagacag tattgtatct
    23941 ttatcgtgtt ccacaactat aacagtatta cccttatctc ttagctcttc tatcattttg
    24001 atgattaaat tatggtctct tgggtgtaaa ccaatagatg gttcatctaa aatgtaggtt
    24061 aagcctacta attcacttcc tagctgactt gataatcgta ctctctgcag ttctcctcca
    24121 gataaagttg gagctgttct atctgttgat atatagctaa gacctacctt taatagataa
    24181 ctaactcgaa tttttaattc tgttaagata tcatttacca aagagagctc atttttttga
    24241 agttgatttg gtaattcaca caaccaattc cataactgtt ctatcgtcat ttttgttagt
    24301 tcagggaagc gataaccttt gattgtagtg aatctagcct caatgcacag caattcgcca
    24361 ccacatgtat tgcaaggaat tttgttcata tattgatgca aggtattatt ttcagaacta
    24421 gattctctaa aaagtctttg aatgtggttg attgctcctg aagcaggtct tctaatcttt
    24481 gattcaaagc taaattcata tatcttatcg tctgtaccat ataagattgc atctataaaa
    24541 tctcttggta attcattcca aggtatatct aggtctatat ttttatcttt tgctattgca
    24601 tataattcac ctaccatcca attaccattt ggctttttcc ccttcaattt tccaaaatag
    24661 taagtagctc catctaatat tgaaatagtt gggtctttta caatcaattg aggattaact
    24721 tgataggtaa aacctaatcc attacaatcg tgacaagctc cagtatggga gttagcattg
    24781 aaggttgaag tatttatctt agaaaaaata gtttgacaat gtggacaata attttttgta
    24841 ttattctttt tttctaatgg aattttacaa tatggacagt aactttttcc gattgataca
    24901 aataacattc ttaaataatc ccaaatgctt gtaagagtac caacagtaga gcgaggattt
    24961 tggcttcctt ttttctgttc gatagctata gtaggggtta atccctgaag taaatcaaat
    25021 tccggttttt gaagctgttc tgaaagtttt gctccattac ttagattttc aaaataacgt
    25081 ctttttcctt cttcataaat cgtatcgaaa gctaaagaag attttccact accacttaca
    25141 cctgtaataa cagttatttg attttttgga attgtaacct caacatcctt taaattgttt
    25201 tgccttcctc cttttaaata gatagagctt ttattatgac aaagtgaatt tttaattgat
    25261 ttatttattg attttgtaaa tttgaatttc ttttcgagtt caagaggatt gcctaattct
    25321 tttatttccg aaatgcctaa tatttttaac tgagaaaaga ttgatttcaa ataatcttca
    25381 ggcaattttt ctattaacaa attaaggtct tctattttta tatttccgct tgataatatt
    25441 tctgccattt catctaataa atttttttct gctcttgtta attgattgta ttttttggaa
    25501 cttaattctg tccataaatc ccatggaagc aattctaaac caatcatatt attaaagtca
    25561 tgtagaagat taccctttac agaatgccaa cctttccaat ttttattata tccaaagtca
    25621 tcttgatgag catgtccttg ccgacatctt atccaggctt ctgaaccagt taaaaaacca
    25681 tctgtttttc cgacatcatg agtgtcaaaa ttaatttgaa aataattttt ttgtatgtca
    25741 tctatttgtg catctattct tatccatctc tttgttagag tatcatagta ttctacaagc
    25801 cagtggtctt cataagtaag ctcactttca aaataattag caaaacctgc tctcattcta
    25861 gcctcaaaac ctcgatatct taggagcgat acaagaagta aagaataatc tctgcacatt
    25921 ccaacaagcc tttgttttgg gtttcttgga atagttagtg ggttagaatt tatttcaaat
    25981 attcttttta acatttgagg aattgtacga agcaattcct catcagattg ttgtttatta
    26041 aaggatatac catataattt tccttggtct ccatgaatta ctaggctttg aaccactttt
    26101 aataactcaa ttggagtctt tggtaaatct tgatatttat tttcaaattt tttaggattt
    26161 gtgatgatgc tttgattttt atagttattt attttcattt atatttcacc tctctaaatg
    26221 gatgatatac cctgacatgg tgtcatatgc aagggcaatt taaatttttt ggccaaaatt
    26281 taaaaataaa taaaaaatga tacagtgata aattgtaata caaatatagt ttcaaattgc
    26341 atataatata attatttaat aaaaccatta tctatggaat gttaatgaaa tgttaagatg
    26401 gcattcttga atattaagaa atagaatact ataatatagt gtgaaggatt tttagtaaaa
    26461 aaatttgtaa gtgttaatat acattaaaaa atagatttat aatttggagg aaaaaaatga
    26521 aattatcaag gtataagaaa aatagtttag ttctgtctat aattttatgt tcacttatta
    26581 tttcaatcct tgtaattact gtttttaata ccgtaaaact acacaatata tctaataaac
    26641 aatctaaaaa ctatttaaat gatgtatcta cacagattgt aatgaatgtt gattctaaaa
    26701 tcaaatttat tttatccgac ttaagaataa tggcagattt tattaagcaa tatgaaggtg
    26761 atagtcgata tgagtattta tctaaaagaa agactagtta taagtattat gatgttggaa
    26821 taatagattt agaaggtaaa gctgagtttt taagtggaaa aaagtttgac ttaaagaata
    26881 ctgtttccta taaaaaagga attgaaggta aagaatactc agaagtaata gagtcaatgg
    26941 gttttgttct ttatagtgta cctatattta atgataatca tgaagtatct agtattttaa
    27001 taggtgtatc caataaagaa agtatgaatg agattcttaa tatagataac tttaatggaa
    27061 aaggaactat tgaaattatt aatagtaagg gaaaacctct tttcatagga aaaaatactg
    27121 aattaataaa ggaccttagc cataaatata agagttctgg agatgaacct tgggcacaaa
    27181 agatgcttga ggattttaaa aatgataaat cagggaatat tacaataacc tcatcaaaag
    27241 gtgtacaatg cttattaact tatcatccaa ttacaagagg tttaaatgat tggcattttc
    27301 ttctcatagt acctgaagat gctgtacttg gtgaacttaa taaattaaac tcttttacaa
    27361 taacaatgac atttataatt acatgtatta ttggaattat aacattaatt ttatatatta
    27421 taagaagaaa atatgtaaat caaatagaaa atattgcata tttagatagt ataacaaatg
    27481 gtataaattc aactaagttt agtatgctag tcaaaccttt aatttcagaa tcacctgata
    27541 gtacttatat gatgatagca atgaatataa aagattttaa gctaataaat gattgtttcg
    27601 gtagtgaaaa gggaaatatg acactaaaac atctttacaa tattttgtat aaaaacattg
    27661 atgaaaatga agagtttgtg tgccgtcatg atgcagacct tttctatttg cttattaaga
    27721 atagaccagt gttagaagcc ctggagttat tatataaaat agaagctgac acaaattatt
    27781 ttaataaaaa tagggaaaat ccatactttt taagactatc agtaggtatt tacacaattg
    27841 aaaatcataa tgaagattta attacaatac aagaccatgc aaatacagca agaaaaagct
    27901 ttaataaaac tcatcaaagt gatttttctt tttatagtga tatagaaaga aaacgattaa
    27961 tatctgaaaa ggaaatttca aatttaatgg aaaaagccct tgaaaataaa gaatttttta
    28021 tgtgcttaca acctaaaatt gatataaaaa gtggaaaaat tagtggagca gagtctcttg
    28081 tgcgttggaa aaattcagaa aagggcataa tttatccaag tgattttatt cctcttttcg
    28141 aaaaaagtgg atttatatgt aagttagatt tatatatact agaagaaaca tgcaaattga
    28201 tttctaagtg gataaaagaa ggtaaagaag tgttgagaat ttctgttaat gtatcacgtc
    28261 aacatctgaa tgataaattg tttttagaaa aatataagca tatatgcaat aaatacaatg
    28321 taccaacatg tctgatagat ttagaactta ctgaatctat tttcttagaa aatccagaag
    28381 ctatagatat aatagaggat attcattcta atggatttaa atgttctata gacgattttg
    28441 gatttgggta ctcatcatta gggatattaa aggattttaa agttgatata attaagttag
    28501 accgttcatt ctttgttagc aaaaataata tagaccgtgg taaggtagtt attaagtcta
    28561 ttattgaact tagcaaaagg ctaggtatga aagtaactgc tgaaggaatt gaagaattag
    28621 aacaagttga gttcctaaaa aatgtgggat gtgattatat tcaaggttat gttttttcaa
    28681 aaccattatt aatttctgac tttgaaaatt ttgcatatga aaataataaa attaaaaata
    28741 tccattatta aatgtacaag ataaaaaatt taggcaagtt atataattaa aaatataact
    28801 tgcctttttt atttatatat ttaataaaaa tatatttgca gattttgtaa aaataatttt
    28861 caaatgttgt aagttgtggc taaagcttta ttgtattatt ctgaatatag aaagatagtt
    28921 actgtcttag ataaaaactg aaacatacat aataatataa aatttgctat attaataact
    28981 ctaattattt tggaaggagg gaaaatatga taagtgggag aatgttactc atcatgaatt
    29041 ttctaaaagg aaaaaataag acaagttaca aggatattag caaacaactt agtatagaag
    29101 aaagaaaagt tagatatgat ataaataatt taaatattgt tttgcgttca ttaaacaagt
    29161 cagtaataca aaagatgaac aaaggtgtgt taattattcc tgatgacttc caagtagtat
    29221 gtataaataa taacgaatat gtattttcct taactgagcg agtatctatt atgaaaatta
    29281 tatcaatgtt taaaatagat aatctaaact tagaaaaatt aagtaaagaa tttcaggttt
    29341 ctagaagttc aattaaaaat gaccttaatg ttttgtcaag tgaattagaa agaaaccaaa
    29401 taactattac ttatgataaa tcttttaaaa taagtggaga agaagacatt atatataagc
    29461 aaagattgaa catattaaaa tcgtattctt atctttttgg taaggaaaaa tctgatttaa
    29521 gtgtatttga gaagtattta gtgaatgtaa ttgaaaaaat attcaaaggg atttatttga
    29581 ttgatatata taattggtct atgaatttat tattgcaaat gggatggact ttaaatgatg
    29641 aatcttttac atggtatgtg tcaaacattt tcctttttac atggtatata cattcagatg
    29701 aaaaacatcc tttagaatct gcttcattaa gtgagccgtg ttttgaaaat aagtttgacc
    29761 aagaatttga aacaattatt caaaaaaagt tgactaagga acaaattttt ctgttaaaga
    29821 gttttgtatt ttttacaaat aaatatgcaa gtttaaacga ggatatggat ttgattagta
    29881 cagaaattat agttcaagac ctaatttaca atatgtcaga aatattagag attagcttta
    29941 aagaagatat gattctttat aaaggattac tcaatcatat tgccccattg atagagagaa
    30001 tcaagcagaa tatacagatt tatgaggaat tacttcatgt aataccagat aaatatcaat
    30061 atgtacttga agctactaag gtttctattc aaaaaaacag agttttaagt caaataaaga
    30121 atgaaaatga aacaatactt ttggcaatac atttcttagg aagtatacat agaaatgaga
    30181 ggaataacta caaaaatata ttgttagttt gtggatttgg atatggtgta attgctatgt
    30241 taaaggatag tttagtaaat gattaccaga taaatatagt agagagtatt ccatcatata
    30301 agttacaaga ttataaagac tgggaaagta ttgacttcat tataacaaca tcaaagatag
    30361 taatagactt gcctaaaaca attattgaga taaatccatt tttacaagaa gaggattatt
    30421 tgaagtttga agaaaaaggg ataaaaagaa agaatgtctt aactaattat atgtcaataa
    30481 aaaaaaggtt ggacttttta gaagaagatg cccaaaaaag agtattaagt attatatgtc
    30541 aagaacttgg atacagtgat gagagaatat tatttagaca acttaattta agtgatttaa
    30601 tagggattga taccataagg ataattgatg gagatatgaa atgggaagat gctgtaaaat
    30661 ttagttcaaa catacttgct aattgtgatt ttgtatcagc acaatatgct gagaatatta
    30721 tagatatttt aaaaaatgtg ggtttttatg ctgtaaaaga taacgaattt gctttactac
    30781 atggcaatga tagttcatta gtcaaagtaa gttcgataag tttattaata tgtaaagaag
    30841 cagttagttt tggagataaa aaggttaaaa tcatattttg cctagcaagc agagataaaa
    30901 aagagcaaat tcctgcaata attaatctaa ctaaaatggt ttataagact aattttattg
    30961 ctatgttaga aagtgcaaag acaaaagaag aagcagaagt tttaattcat aaatatgaga
    31021 aggaggtcac tgtatgaata aattagttaa tgtaaaatgt tcatttaaaa tacatgttaa
    31081 ttcaaaagaa gaagccatta tatcgttagt tgatgtagtg tcaaaagaag gatatttaat
    31141 agataaaaat caatttttaa aagatgtttt aaagagagaa gaaacattgt cgacttatat
    31201 tggacatggt ataggtcttc ctcatagtca aagtgtaggt gttaaaaact cttgtattac
    31261 aataggaaag cttgatactc ctattgaatg gacagaagaa ggagaaaaag tggatttaat
    31321 atttttgata tcagtaacaa aagacaatga aaataatctt catttaaaga ttttatcaaa
    31381 attagcacgt ttattgatgc atgaaagttt tagaaatcaa attagatgtt cagatgaaca
    31441 aactgtttat aatcttataa aagaaaaaat agaggaggaa gattaaaatg agaattttaa
    31501 agtttttgca aaaacatctt atgacagcaa catcttatat gattccattt gtggttgcag
    31561 gaggaatatt atttgcttta tcagtaactt taagtggaca agctgctgtt cctgaaacag
    31621 gctggttggc taaactgaat caaattggag ctgctggctt ggctttattc attcctatat
    31681 taggtggata tatagcattt agtatggcag ataaaccagg attagctcca ggtatgatag
    31741 gtgcatattt agcaaaagaa gtaaatgcag gttttatagg tggtatcata gcaggattta
    31801 tagcaggatt tgttgtttta caattaaaga aaattaaatt agctcctaca atgagaactt
    31861 taggttctat atttatttat cctttagttg gtacattgat tacaggtggt ataattgtat
    31921 ttttaattgg agaacctata gcttctttta tgacatggat gacaaactgg ttaaatggaa
    31981 tgtctggtgt ttctaaaatt cctttaggtg gaatcttagg aggaatgata gcctcagata
    32041 tgggtggccc tataaataag gttgctgcta cttttgccca aactcaagtt gacacacttc
    32101 catatttaat gggtggagtt ggcgttgcaa tttgtatacc tccaattggt ttaggattag
    32161 ctacattatt gtttccaaaa aaatttagca aggaagaaag agattcaggt aaagcttcac
    32221 tattaatggg atgtgttgga attacagaag gagctattcc atttgcaaca tcagatccag
    32281 ttagagtaat accttgtatt atggctgggt cgattgtagg aaatattatg gcttttttat
    32341 taggatgttt aaatcatgca ccctggggag gtctgatagt gttacctgta gttgacaata
    32401 ggttggggta tattgcatca gtattaactg gagcagtagt tgttgcggta ttaatgaaat
    32461 tagtaaaaaa agacgtgaaa gaagatgaag aaattgaaga agatttagat gaatcaattg
    32521 aattaatatt tgaagaatta taaatataaa tggaaggaat ttgtataaaa aagtaaatat
    32581 aaaactataa atttaaagga gataagaata tgaaaattgt agcagtaaca tcttgtccta
    32641 gtggagtagc acatacttac atgtcggctg aatcacttga attatcagcc aaaaaatttg
    32701 gtatagaaat aaaggttgag actcaaggaa gctctggaat agataatgaa ttgtcactta
    32761 aagatattga tgaagcaact tgtgtaatat tgactaatga tgttgagatt agaaatatgg
    32821 aacgttttaa aggaaagaag gtagtaagaa tgagtgtatc tgagataatt aagaaatctg
    32881 atgcattaat taagaaaata aaagatactt ttcaataaaa attgatttat tttacatata
    32941 actcaaagat gtttttaaag aaatttttat taaaagcatc tttgaaaata tcttaaaaat
    33001 agaataaaag gagatatagt catgaaaaag ttaccaataa agactgtcgt gcaaagatta
    33061 ctaaacttac aagaagaggg gaaaagtgca actcttttag gaattggtcc tatgtcacca
    33121 aacttgttac aagcaagttt tgaactagca aaagatgatg attttccttt aatgtttatc
    33181 gcaagtagaa atcaagtaga tgcagatgaa ctaggtggcg gttatgtaaa tggttggaat
    33241 caggaaactt ttacaaaaga tattaagaag gttgccgaca aagttggatt tgatggttta
    33301 tattatttat gtagagacca tggtgggcca tggcaaagag ataaagagag aaatgaccat
    33361 ttgcctgttg atgaagcaat ggagttagga aaaaaatctt atttagcgga cattgaagca
    33421 ggttttgacc tattgatgat tgaccctaca aaagacccat ttgaaattgg aaaagtaatt
    33481 ccactagatg tagtactaga aagaactgta gaattaattg agtattgtga aaacgagaga
    33541 aaaagactta atctaccaga cataggttat gaggttggta cagaggaaac caatggaggt
    33601 ctgacttcaa ctgagacgta tgaaacattt ataactagac taaaggttga actcgataat
    33661 agaggtttgc caatgccaac atttatagtt ggtcaaactg gtactttaac tagaaagaca
    33721 gaacaagtag gaacttttaa ttttagaaat gcttatgatt tagctcaaat ggctaagaaa
    33781 tatggagttg gtttaaaaga gcataatggc gattacttag atgatgtaac tttattagaa
    33841 catataccat ctcaaattat tgctacaaat gtagctcctc aatatggtac tgaagaaact
    33901 agggcatatt taaaattagc agaagttgag tgtaaattag aaaaagaggg cttagttgag
    33961 aaaacttcta atatcagaca tgttcttctt gttaatgcaa ttgaatgtgg acgttggaga
    34021 aaatgggtag taggagaaca aaaaaatcta actactgaag agatatttaa ggatgaagtt
    34081 ttatctaatg aaatactaga tattgcagga cattatacat ttaataatga tgatgttaaa
    34141 aaagaaatag aagtgcttta tgataattta agtaagaata atattgatgg tcaaagattt
    34201 gttgtagacc atattaaacg tcctttgcgt gattatgcag aatgctataa cttaaaaggt
    34261 gttactacga ggattttaaa taaataatag gacttatagt ggtgagtatt gttatactag
    34321 gtatttatag ttataattat acttaccact attaaattta ggaggactaa tattttgatt
    34381 aatttaattt ttgatgtaga tgatacttta tataatcaat taacgccttt ttacactgca
    34441 tataataaag tgttttcttc aataaaggat atttctattg aagatttata tatgagtagt
    34501 agaaagtata gtgatgaggt atttcatatg actgaaaatg gagaaatgcc aatcaaagaa
    34561 atgcatattt ataggataat gaaagctttt gaggagttgg gaaattctat tacagaaaaa
    34621 gatgcacaaa gttttcaaga tgagtatata tatcaacaat cacaaattac actaatacca
    34681 gaagttgaga ggattttaaa tttttctaaa gaaagaaata ttaatctagg aattataact
    34741 aatggcccat caaaccatca aagaatgaag ttaaagcagt taaatattga aaactgggtt
    34801 gataaaagta atatttttat ttctagtgag gttggatttt ctaagccaga tactaatatt
    34861 tttagagtag ctgagaatgt tatgaattta gatagagaaa atacatatta tgtgggtgat
    34921 tcttatagaa atgatgtatt aggtgctaaa aaagctggtt ggaagagtat atggttgaac
    34981 catagaggac atgaggtaga agagttgttt tacaaacctg attttgtaat tttggaacat
    35041 aaggatttga tatctttatt tataaaaata tgtagttata aaaatatgta gtaaaaaaat
    35101 gttaataata gaattgtata aaataattaa taataactat ataaaattat atgtttagat
    35161 tgtgagcaat ctattttatg ttaaaaatag attatttaga agaaggggaa atcttaaaaa
    35221 aatttgaata tccccttttt attatttaat taaaatgaaa tagttagaaa tatattttat
    35281 ttagtttagt caataacatt ttgggattct ttataactac atgttaactg ttgaataggt
    35341 ttatcatatg gtttaaccca tcctttatta atacttaatt ctgtaagtgc tgtgtgacct
    35401 tctaccattt gagttaatga agctgaatat atagctctta attcaggtgt actacttgtc
    35461 aatgcagaat taagatacat attggcagat gctttagcag atgaaagcat acttaacatt
    35521 attactttat cgtctatata agtattgttc ttaattagat tttctatcat atttctcatg
    35581 ttatctatac ctcctcagaa attagtattt cattttcaac tataaattgt tgcatagctt
    35641 taattcttcc ttctgttgct aatatactag attctgattg tctttttagg tcttcatctg
    35701 atattaacat atttattgct ctttgcataa gtaatccgtc agactccatt tttataactg
    35761 ctgctaaaga tattttttca gtttctgaaa gtattctcat ttaatcatct cctatattgt
    35821 aatttatgct ttaatagtat gtctttcttt tcaaggaaat aaccattaca cttttttaca
    35881 gtattttata ttctctttat atcaaaattt agtcgaccta atatattaat aataattttg
    35941 taggatattt atcattaaat atctataaaa taaattattt gaatattcat aaagcaaaat
    36001 ttatttgtat gtacttcttc aagagtcaat atgagttttt tcaaaaaatt aatttttatg
    36061 ataatcatta agggctatat ttttcttaaa gttgtgatta tcattattaa tttacaataa
    36121 aattgccgaa aagccctctc ctttaggtgt agggatgaaa ggtaaggtct taatataaaa
    36181 aaagttagaa taatgcttgt aatctaatac cgctactgat accctatatt taggaggtgt
    36241 tagtttttat gtataaatct aacaaaaata tagtttatga ttgcaaatat catattgtat
    36301 tttgccctaa gtatcgtaaa cctgttttag ttggcgaagt tgaaaagatg ttaaaagaaa
    36361 tactaccata taaagcagat gaacttggag cagaaataat agaaatggaa actgataaag
    36421 aacatgtgca cttattaata tcttgtgacc ctcaatatgg aattcataaa gtagtaaaag
    36481 gtttaaaagg ctttagttcg agagtattaa gagagaactt tccacattta aagtctagta
    36541 tgcctagcat gtggactaat agctattttg taggtactgt tggttctgtg agtttagaag
    36601 tagttaaaca atatatagaa aatcaacaag ttaggacaaa gaaatgataa aaactcatag
    36661 agtgaaatta aacctaacta gaacacaatt tgaattagta agggaaaagc aaatggaaag
    36721 tgctaactgt tggaactaca tagttaactt atctaaagaa tactattttg aacataaaca
    36781 atggattaaa aagaatgata tacaaaagtt aatcaaaggt aagtacaatc ttcatagtca
    36841 aactattcaa gctatatcag ataaatttga tgcaaataga aagactatat cagaattaag
    36901 aaaaaaaggt aatactaaag caaaatatcc atacaagact aagaaatttt atataatacc
    36961 ttttaaagct agtgctatta atagaaatgc taaaggcaac ttaaaattat caatgtcaaa
    37021 aggcaggtat ttagaattag attttaatgt tgagaatata aaaactgctg aaatagtatg
    37081 gcgaaatgga tattatttat actacacttt tgacaatgaa ttaaatggag ttgtagccaa
    37141 aggcactaat accgtaggtg tagacttagg ggaaatacat tcgatagcta gtgtaacaaa
    37201 tgaaggtgta gggcttattc tatctaatag agaaggcaga agtattaaac aatttagaaa
    37261 taagatgtat gcttatatat ctaaaagatt aagtaaatgt aaaaaaggta gtagacaatc
    37321 aaagaagtta tggagattaa aaaataagat aagaagtaaa acagataatc agttaatgaa
    37381 tttatatcat caaacaacta gaaagtttat agacttttgt gtagagcaga aggtatgtga
    37441 aatagttctt ggggatataa aaggggttga aaaagatact aagaaaaaga aaagattaaa
    37501 cagagttaat agacagaaaa tatctcaaat ggagtatggt cgaataaagg actatataaa
    37561 atataaagca aaagagcaag gtattgaagt taagttagtt aaagaaaact acacttctca
    37621 aacttgccca aagtgttcta aaaaacacaa accaactggt agaacttata gttgtacttg
    37681 tggttatgaa actcatagag atatagttgg tgcttggaat attttaaata aaaagcataa
    37741 atatggttta gtagatttta gaataaatca taagcaacca ataaatttaa aagtatctac
    37801 cgtttgagcc atgtgtgggc gaataacttt aaggtagtag tggcgaagac accgtccgaa
    37861 gtagcttggc tttgtaacca cctctgttgt actgtttaag tataaataag tgtgttagcc
    37921 accaagaatc cccttgcttt agctatgggg agtgtgtcaa taaaatactt taatgaaaaa
    37981 tagctaactt taattgtagg atattcttaa tatatttgaa ataaataaaa atattgaagg
    38041 atataatatt caattggtat ataaataata aatgatagtt aaattttacc ttagaggcta
    38101 attaggtgtt tagtcaaagc taatgccttt agaatacaaa tgtattctaa aggcattttt
    38161 actatgtatt ttcatttata ttactaaaca ttatctattt ttatatacat ttctatgtat
    38221 tttattttca tcaaatcggt ctataaactc atttttttct tcactatatc caatagatat
    38281 aagtgcataa ggaactaatt ttaatggtaa gtctaaagtt tgtctaactt tatttaccac
    38341 tttattttta ggaaatactc ctgcccaaca agcagctaga ccttgattag taacttctaa
    38401 taataaattt tgtgtgcaag cacctaaatc ttgtatccat ttaccaggtt ttaagaattt
    38461 atctctattt ccaagcacta ctatacataa tggtgcaaat tctatatgct ttgctctatg
    38521 ctgtgacttt gagagctgtt tcagcagttc cttatcatct actataataa attcccaagg
    38581 ttgagcattt tttgatgaag gtgcttgcat agctgatttt agtatttcag ttattttatc
    38641 ttcttctata tttttatcta tatatgttct tattgaacgt ctatttttta taacttctaa
    38701 catacagatt ctcctttaaa taaaattatt tctatttata taatatcatt actttaaatt
    38761 ttagctatta cttatataaa gaataaactt tgtgttggtt ttatctaagt aaaagtaaca
    38821 ttcagaacta aaaaacaaga ctataaatcc aaagtattaa ttaaaaaaga agtaataaaa
    38881 aataatatac aagatttaaa aaagagtatt gggcttaaaa tttaattaga aaaccaattt
    38941 tgagataatc tgttttttat tttaacaaaa aaacacaaat aaagttcgat acgtagcgaa
    39001 tgaaaaaatt acaagaaata ttttttttaa aaaatttcaa aaaagagttg ataatatatg
    39061 tatattaata taaaatttaa ggtgtataat tcgtataata atacgaatga tttgtagtgt
    39121 aaaataactt ataaacggag aggggaagtc taatgaaagt agcagtagtt atgggttcaa
    39181 aatcagatta tccaaaatta gaagaaggga taaaactgct tgaaaaatat ggaatagaag
    39241 ttgtagcaag agcattatca gctcatagaa caccagaaca actttcaata ttcctaaaag
    39301 aaatagaaga tgatactgat gtaataatag cagcagcagg aaaagcagca cacttaccag
    39361 gtgtaatagc ttcacaaaca ttaattcctg taataggatt acctattaaa tcatcaacta
    39421 tggatggact agactcactt ttatcaatag ttcaaatgcc aaaaggaatc ccagttgcaa
    39481 cagttacaat agacttaggt ttaaacgcag ctttattggc attacaaata atgactttaa
    39541 aatacccaaa attaaaagag gatttgaaat catatagaga agagatggca caaaaggtgt
    39601 tagaagacga caagaattta agggggtagc agaaatgtta ttatatgaag gaaaagcaaa
    39661 acaagtatat tctacagata atgaaaatga atatgttgtt tattataaag atgatgcaac
    39721 agcatttaat ggagaaaaaa aagcagaaat atcttcaaaa ggtatactaa ataataagat
    39781 atcaacaata atctttgaaa tgttaaaaga aaataatata aatactcact ttataaaaag
    39841 tttatcagat agagaaatgt tagttaaaaa agtagagatt ttaccattag aagtaatagt
    39901 aagaaatatt gctgctggtt ctatctgtaa aagagttggt cttgaagaag gtgtagtttt
    39961 cgatgagcca atttttgaaa taagctacaa aaatgatgct tatggtgacc caatgctaaa
    40021 tgatgattat gcagtggcaa tgaagttagc aactagagaa gagttaaaat tcttaagaga
    40081 agaaacttta aaaataaatg agttactaaa agcatttttc ttaaaattaa acctaaagtt
    40141 agttgacttt aaaatagaat ttggtaagga ttctgaagga aatataatat tggcagatga
    40201 agtatcacca gacacttgta gactttggga tgtaaataca aatgaaaagt tagataagga
    40261 cagatttaga aaagaccttg gagaccttgt agaaggttat acggaagtac tttcaagaat
    40321 gaataataaa taggaggcaa atgtatgtgt ggagttttag ggatttactc taataaagat
    40381 gtaactaaag aactatatta ttctttatat tctatgcaac acagggggca agaaagctgt
    40441 ggtttagctc ttttagatga tggagaaatt aagtacaaaa aagatatggg attagttgga
    40501 gatgttttta aggaaaatga attatctaag ttaaaaggaa atatagggat tggacatgtt
    40561 agatattcaa cagctggagg aagtcatgtt tctaactgtc aacctttagt tggaagttgt
    40621 agaaaaagac aattagccat agctcataat ggaaatctag ttaatgcaaa ttatttaaaa
    40681 gatatgctag aagaagatgg atatatgttc caaactaatt cagatacaga agtgatttta
    40741 tatatacttg ctagatatta caaaggggat atagtagaaa gtttaaaagt gacaatggat
    40801 tatataaaag gtgcatatgc tcttgtaata atgagtcaag aagaattggt tgcagttaga
    40861 gacccacatg gattcagacc tcttgtactt ggtaaaaagg gtgatgaata tatatttgca
    40921 tcagaaaatt gtgcaataga tatacttggc ggagaagtta taagagatgt agagccagga
    40981 gagataatag tagtcaaaga tggagaacta aaatcatatt tttattcaga aaattataaa
    41041 ccagttaaga aaagttgtat atttgaacac atatactttg caagaaatga tgcaactata
    41101 gacaatgtaa atgcatatga atttagaatt aaatgtggtg agagattagc tcagaatgaa
    41161 actgtaaagg cagatatggt agttccagtt ccagattcag gttggccagg agctattggt
    41221 tatgcaaatg ctagtggatt aaaaataagt gaaggcttag ttaaaaatag atatgtagga
    41281 agaacattta taaaacctac acaagaagaa agagaaatag cagtaaaaat aaaattaaat
    41341 cctctttcaa caataataaa aggaaaatct ataattttag tagacgactc aattgtaaga
    41401 ggaactacat ctaaacaatt agtaaaatct ttaagagaag caggagcaaa agaaattcat
    41461 cttagaataa cttctcctcc agtagcttac tcttgttact atggaataga tactccaaat
    41521 cgctctaaat taattgcatc aagtaacaac gtagaagaaa tgagagaata tattggatgt
    41581 gatagtttaa aattcctaga tatagaagga atgttagatg caacagaaca taagtctact
    41641 ttctgtaaag cttgttttga tggagaatac ccagttaaga aaattgataa ggaggaacta
    41701 ctttcatgtt aacatataaa gaatcaggtg tagatataga tgaaggaaat agagcagtag
    41761 accttataaa aggtaaaata aaaggaactt atgatggaaa tgtagttgga gatttaggta
    41821 acttcagtgg attatacagt ttaaaagatt ttgtaggtat gaaagaacca gttttgcttg
    41881 catctacaga tggtgttggg actaagttaa aaatagctca gatgatggac aagcatgata
    41941 ctgttggaat agatttagtt gcaatgtgcg tgaatgattt aatttgtcaa ggagcaaaac
    42001 cattattctt ccttgactat atagctcttg ggaaattagt gcctgagcat atcgaaaaaa
    42061 tagttggtgg aattgcagat ggttgtaaaa tgtctggttg tgcactaatt ggtggagaaa
    42121 ctgctgaaat gcctggaatg tatggagaag atgactatga tttagcagga ttttctgtag
    42181 gaatagcaga caaagaaaag attgtttctg gaaacaatgt taaatcagga gatgtattgg
    42241 ttggtatatc ttcaagtgga gtacacagca atggattttc ttttataaga aagatatttt
    42301 tagaaactta caattataaa atggaacaat atgttgaaga actaggaatg acagttggag
    42361 aagcactttt aacaccaact aaaatatatg ttaaattagc tttagatgta ttagctaaac
    42421 atgacataaa agctatagct cacataactg gtggagggct tatagaaaat ataacaagag
    42481 ttatacctaa agggttagga ctagatatca ataaaaaatc ttgggagaag cctcctatat
    42541 ttaaaatgat agaaggtttt aatgctgttg atgagagaga acttcataag agttttaaca
    42601 tgggtattgg gctagtttta atagtagata aagaaaatgc tgatgatgtt gtaaacttta
    42661 taaataatag agaaaatgac aatgctgctt atgtagataa aaaatatagt gaattattag
    42721 aagataaagc ttatataatt ggtgaagtag tagatagtca tgaaggtgta gaattatgct
    42781 aaatatagga gttttaatat ctggtggagg aacaaattta caagcagtta tagatggtac
    42841 tgagtctgga gaaataaaag gtcaggttaa agtagttatc tcaagtaagc aaggtgctta
    42901 tgggctagag agagctaaaa atcataacat aaaagcaatt tgtgaaactg atgaagacaa
    42961 gataatagaa attcttaagg aaaataaaat agatttagta gttttggctg gttatttaaa
    43021 aataatcagc ccaaagctgg ttaacgagtt tagaaacaaa atgataaaca tacatccatc
    43081 attaattcct tcattttgtg gagctggatt ctatggagaa aaagttcatc aaggtgttat
    43141 agattatgga gctaaagtaa ctggtgctac agttcatttt gtagatgaag gtgctgatac
    43201 tggaccaatc ataatgcaag atgtagttaa ggtaaatcaa gatgatgatg caaagacact
    43261 tgcaaaaaga gtgttagaag ttgaacatag gattttaaaa gaaagtataa gtcttttttg
    43321 tgaaaataaa ttaaaacttc aaggtaggag agtgtttata aatgagtaag agagctttaa
    43381 taagtgtaac tgacaagact ggtgtagtgg aatttgctaa agagttaaat aaattagatt
    43441 atgaaattat atctacagga aatacattta aaacattaaa agaaaatggt gttaatgtaa
    43501 tgcaagttga agatgttaca aattttccag aaatattaga tggaagagta aaaacattaa
    43561 atccatatat acatggtggt atactttata aaagagataa agaatctcat gtagaaactg
    43621 taaatgaaca caaaatacat tcaatagatt tagtagctgt aaatctatat gattttgaag
    43681 gaactttaaa agctggaaaa agtcatgatg aaataattga aaatatagat attggtggac
    43741 catctatgat acgttctgct gccaaaaact ataaggatgt aatagtagta gtagatataa
    43801 aagattatga ttctataata gaaaaattaa aaacagatac aatgacatta gaagacagaa
    43861 aaaaattatc atataaagct ttctcaacta caggaagata tgatgcgtta atatctagtt
    43921 attttgctgg agaagttgga gatacgtatc ctgacatatt aaatttaact ttccaaaaag
    43981 aacaaacttt aagatatgga gaaaatccac atcaaaatgg tttcttatat tcacagtcaa
    44041 atgcaaaaaa tccaatctta aattatgagc aattaggcgg taaagaactt tcttttaaca
    44101 acttaaatga tttacatgga tgtttagaag taatgagaga atttaaagat agtgaagaag
    44161 tagtttcagt agctataaaa catgctaatt catgtggggt aggtttagga aaagatgctt
    44221 ttgaagcata tacaaaatgt tatgaagcgg ataaggtttc aatatttgga ggaatagtag
    44281 gaataacttc tactatagat aaagctacag cagagaaatt aaatgaaata ttcttagaaa
    44341 tagtagtagc atatgatttt gaaccagaag ctttagagat acttaaacaa aagaaaaatc
    44401 taagaatatt aaaattagct aaaatagaaa atagtttaca accatatgaa atgaaatatt
    44461 tagatggaaa attattgata caagatagaa acaatatatt agcagaaaaa agtgaaaatg
    44521 taacaaagga aaaaccaaca gatgcacaac ttaaggacat ggaatttggt atgagagtag
    44581 taaaaaatat gaaatcaaat gcaattgcag tagtaaaaaa tggacaaact ctagctttag
    44641 gttgtggaca aacatcaaga atttgggcat taaaaaatgc tcttgaaaat aacaaagata
    44701 aagattttac aggagctgtt ttggcgtcag acgcattttt cccatttgat gattgtgtaa
    44761 cattagctca tgaatatgga atatcagcag tagttcaacc aggtggctct ataaaagata
    44821 aagattcaat agaagcttgt gacaagtatg atatggttat ggtatttaca ggaataagac
    44881 acttcaaaca ctaaggagga tattatgaag atattggttg taggcggtgg cggaagagag
    44941 catgctatat gctggaaact aagcaaagaa aaaaatgtag aaaaaattta ttgtgcacca
    45001 ggtaatgcag gaattgcaaa cgtagcagaa tgtgtaaata taggtgatac taatatagaa
    45061 gaacttttaa aatttgccaa agaaaatgaa ataggtctga caatagtagg accagaagta
    45121 ccactagtta tgggaatagt agatgagttt gaaaaagaag gattaagagt atttggacct
    45181 aataaaaaat gtgctcaact tgaaggaagt aaagcttttt caaaagaatt tatgataaaa
    45241 cataacatac ctactgcaaa atataaagaa tatacaaact tagaagaagc tatatcagaa
    45301 atagatagtt ttggatatcc agtagtaata aaagcggacg gattagctgc tggaaaaggt
    45361 gttgtaatac ctgaaaatag agaagatgct atagcaactt taaaagaaat gatgtcagat
    45421 aagaagtttg gagctgctgg agataaaata gtaattgaag agtttttaaa aggaatagaa
    45481 acttcaattc tagcatttgt agacaatgat acaatagttc ctatggcaag tgcaaaagac
    45541 cataaaaaag taaacaacta tgagcaaggt ccaaacactg gaggaatggg aactttttca
    45601 cctagtgaaa tatatacaga agaattagca aataaagtaa aagagacagt attagaaaaa
    45661 actttagaag gtttcaaaaa agatggactt aattttaaag gtattttatt tgttggtctt
    45721 atgataactg aagatggaga aaaagtactt gaatataatg taagatttgg agaccctgag
    45781 acacaatctg ttttatttag attagaaaca gatttacatg agataatgga agctatacta
    45841 gataataagt taaaagatat agaaataaac tatagtgatg atgaagctgt atgtgttatg
    45901 cttacatcag gagggtatcc agacagttat gaaaaaggga aaattataac tggtcttgaa
    45961 aacttggatg atgatatagt agtattccat agtggcacta agatgtttga tggtaatttg
    46021 gttaccaatg gaggaagagt aattggtata actgcaaagt caactagagt taaggatgca
    46081 gcagaaaaag tttatgaaaa cataaagaag ataaactttg aaggaatgca ctatagaaca
    46141 gacataggaa gataattttt ctaaaatgga ggataaggta tgttgaatac tgaaaataaa
    46201 gactcaatgg ttagaagagt attggttgaa aaaagagaag gttttgacct tgaggctaaa
    46261 gctttaaaaa aagacttagt agaaagttta cacatagata atatagaaaa tttaagaata
    46321 ttaaatagat atgatgtaga aggaatatca gaagaagttt atgaaaatgc agcaaagaca
    46381 atattctctg aaccaaattt agatgtagta tattatgaag aaataccaaa attaaatgat
    46441 gaaagagtat ttgcaataga atttcttcct ggtcaatacg accaaagagg tgattgggca
    46501 gctcaatgtg tacaaattgt aaatcaaggg ataagacctg ctattaatac agcaaaagtt
    46561 tatatattat caggcaaaat aactgatgaa gagttttcta aaataaaaga ttactgtata
    46621 aatccagtag atagtagaga agcatcttta gagaaaccag aaacgttaaa aatggaaact
    46681 gaaataccaa caacagttga agtattagat ggatttatag atttagatga aaatggatta
    46741 agaacatttg taagtgaaaa aggattagca atgactttag gagacttaca acacgttcaa
    46801 aaatacttta aagatacaga aaagagaaat ccaactataa cagaaataaa agtattagat
    46861 acttattggt ctgatcattg tagacatact acttttatga ctgaaataga aaatgtaaag
    46921 atagaagatg gtaagtttaa tgatatagta aaagaagcgt atcaaatgta tcttaactca
    46981 agagacaatg tatatgtgaa cagacataaa gatatatgtt taatggatat agccactgtt
    47041 gcagtaaaag aattaaagaa aaatgggaaa ttaaatgacc tagatgaaag tgaagaaata
    47101 aatgcatgta gtataaacgt agatgttgaa gttgatggta agatggaaaa atatctagta
    47161 atgtttaaaa atgaaactca caaccatcca actgaaatag aaccatttgg tggagcagct
    47221 acttgtttag gaggagctat aagagaccca ttatcaggaa gaagttatgt ttatcaagca
    47281 atgcgtgtta caggaagtgc tgacccaaga acgactttag aagatacttt acctggaaaa
    47341 cttatgcaaa gaaaaataac tacagaagct gctcatggat atagttcata tggtaaccaa
    47401 ataggtctta caactggaca agttgcagaa gtatatgatg aaaactttgt tgcaaagaga
    47461 atggaaatag gtgcagttat agcagcagca ccaaaagaga atgtagtaag agaaagacct
    47521 gaagcaggag atgtaatcgt tcttcttgga ggaaaaacag gaagagatgg ctgtggagga
    47581 gcaactggtt catctaaaga acatagtgaa gagtcaatct taacttgtag tgcagaagtt
    47641 caaaaaggag atgctcctaa cgaaagaaaa atacaaagat tctttagaaa taaagaagtt
    47701 gctcaaatga taaaaagatg taatgatttt ggagcaggtg gagtttgtgt tgctatagga
    47761 gagattgctg atagcttaga tataaactta gacttagttc ctaaaaaata tgatggactt
    47821 gatggaactg agcttgcaat ttcagagtca caagagcgta tggcagtagc cataaaaaaa
    47881 gaaaataaag ataaatttat acaattagca gtagaagaaa acttagaagc tacgcatgta
    47941 gctacagtaa cagatacagg atatttaaga atgttctgga atggaaaagc aattgtagat
    48001 ataaatagag agtttttaga tacaaacgga gtaaaacaaa ctactgatgt tcatgttact
    48061 aaagtagatg aagaaaatac attctttagc tctaatgaaa tagtaaaaga tgttaagtgt
    48121 gcaagtatga aagacaagtt tacaaaagta ctatctgacc ttaatgtttg ttctcaaaaa
    48181 ggattagtag agatgtttga taatacaatt ggtggtaata cagtacttat gccatttgga
    48241 ggaaagtatc aagcgactcc aacacaaggt atggttgcta agataccagt acttggagga
    48301 gaaactaata cttctacaat aatgacttat ggatacaatc caaaggtagg aaaatggagc
    48361 ccattccatg gtgccttgta tgcagtagta gaatctgtgt gtaaattggt tgctattgga
    48421 ggaaattata gtacaacaag acttacattc caagagtatt ttgaaaaact tggtaacaat
    48481 ccagaaaaat ggggtaaacc attctcagca cttttaggag cgttttatgc acaaagtaaa
    48541 tttgagatac ctgctatagg tggaaaagac agtatgtctg gtacatttaa agatattgaa
    48601 gttccaccaa cattagtttc atttgctgtt gacacagtag atgcgaagaa agtagtatct
    48661 ccagaattta aaaaagcaga ctcaaaagta gtaatgttat gtgtaaacaa ggcagaaaat
    48721 gatgttgtag attttgagga attaaagaga aacttagata aagtaagaga acttatacat
    48781 ggaaataaag ttttatcaac atatgcatta ggatttgcag gtgtaggtga agcaataagt
    48841 aaaatggctt ttggtaataa aataggattt aagtttagtg aagaagctga aaaagcattt
    48901 acagataata aattatttga ggctagttat ggaaatatag tacttgaatt agcaaatgat
    48961 gatttaagta tgttagaagg atacaattat gttgtgattg gaagtacagt taaagaagct
    49021 agtatattta tcaaaggtga agaacttgca ttagatgaat tatataaagc acattgtagt
    49081 actttagagc ctatattccc aactaaaaca gaagaagtaa aatcaaagat agaaactata
    49141 agttatatat cacaaggaga agctaaaaaa tcatcattaa gtatagctac tccaagagta
    49201 tttataccag cattccctgg aacaaactgt gaatatgact ctgcaagagc atttgaaaga
    49261 gcaggagcta atgcaagtat aagagtattt aagaatttaa cttataaaga catagaagat
    49321 tctatagata caatagtaaa cgaaataaaa tcttctcaaa taataatgtt accaggtgga
    49381 tttagtgctg gtgatgagcc agatggttct ggtaaattta tagctactgt atttagaaat
    49441 cctagagtgc aagaagctat aaatgaattt ttaactcaaa aagatggact aatgttaggt
    49501 atctgtaatg gattccaagt attaattaaa ttagggttag ttccatatgg agaaataaga
    49561 gttccaagtg aaagtgctcc aacacttact tacaataata ttggtcgcca tcaagctaag
    49621 attgctagaa ctagaatttc atctaataaa tctccttggt tagctcaaac taatgttgga
    49681 gatattcata atatagcaat ttctcatgga gaaggtaagt ttgttgccag tgaagatgtt
    49741 atgagagaat taattgctaa tggacaagta gcaactcaat atgttgactt taataatgaa
    49801 gctacttatg atattgagtt taatccaaat ggttcattct atgctgttga aggtataact
    49861 agtgctgatg gtagagtgtt tggtaaaatg ggacattctg aaagaattgg tgaggaagta
    49921 tataagaata ttataggtga aaaagaccaa aagatatttg aatctggagt taaatatttt
    49981 agataaagct ttgatgttta attgatagct agaatatata atttagatat ttagatttaa
    50041 agagatgtaa taatatgatg ataatcattt aatattacat ctctttttta tttatctaag
    50101 aaataataag ttcaacctaa gttaaaatac aagctgtgtt ataattaatt attaagtaaa
    50161 attgaatatt tattggaggg caacataatt aatgaaaata ttaataacag ggtctaatgg
    50221 tcaattagga aaagaattgg ttaaccaatt agaagcaatc aatcaaagta taaaccaacc
    50281 aaaatatgtt atattagcta caacaagaag tgatttggac atatccaatc agactaatgt
    50341 agataatttt attttgcata ataaacctga tgtagttgta aactgtgcag catatacaaa
    50401 ggttgatgca tgtgaagata atatcgaaat tgcatacaaa ataaatgctt taggagtgag
    50461 aaatctagca atagcatcag aaaaagttaa tgctaagctt attcacatat caactgacta
    50521 tgtattcaat ggtttttcta aatatccata tagggaagac aataaaactg aacccaattc
    50581 tgtatatgga aaaagtaaac ttatgggaga aaaatttgtt gaacaattct cacataagta
    50641 ctttatattg agaacagcat ggttatatgg taatgggaat aattttgtaa agaccatgat
    50701 aaaactttct ttagaaaata aagaggttaa tgtggttaat gaccagtttg gaactccaac
    50761 aagtacagta gacttagcaa aaattataat aagaatcatg gaaacagaac attatggagt
    50821 ttatcatgct acatgtgaag gtgagtgtag ttggtatgat tttgccaaaa agatatttaa
    50881 actaaaaaat atagatataa aagtaaatcc aattaagagt aacgaattta aatgtaaggc
    50941 tccaagacca ctatattctg tattggataa ttttatgttg aagttaattg gtttaaattc
    51001 ttttagaaag tgggaagaat ccattgaaga atatttagaa agatatgata taaatgaaaa
    51061 gtaaatgtat tattttgaga aaagaaaata agatattata aaaaatataa atatttcttt
    51121 tatttatccg ataatcataa tatgacaaaa acaaatttaa ggatggaaaa agatgaaagg
    51181 aattatttta gcaggagggt ctggtacaag actatatcct ataacaaaat gtatatcaaa
    51241 acaaacactt ccaatatacg ataaaccaat gatatattac cctatgtcgg ttcttatgtt
    51301 ggcagggata caagatatat taataatatc tacaccaaga gatataaaag catttgaaga
    51361 attatttgga gatggaagtt cactagggct taacataaca tatgcaattc aggagaaagc
    51421 aaatggaatt gcagaagcgt ttataatagg agaagaattt ataggaaatg acagagtgtc
    51481 tcttgtatta ggggataata tattttatgg atatggattt agtgaaaggt tggagaatgc
    51541 agttaaaaga aaaggagcaa ctatatttgg gtatcatgta agtaatccaa attcgtttgg
    51601 agttgtagaa tttgataagg attttaatgt attgtcaata gaagaaaaac ctacagttcc
    51661 taaatctaat tatgctatac caggattata tttttatgat aatgatgttg tagagatagc
    51721 aaagctagtt gaaccgtcag atagaggtga attagaaata acctctataa acagtgaata
    51781 tctaaaacga ggaaaactaa aagtggaact tctaggaaga ggtatggctt ggcttgatac
    51841 tggtacacat aaaggtctat tggatgcttc taattatgtt gaagtggttc aaacaagaca
    51901 gggactgtat atagcatgtt tagaagagat tgcatataca aaaggatata taagtagaga
    51961 acaattaatg aaactagcca agccactgat aaaaactgaa tatggtcaat atctattaaa
    52021 attggctagt gaagatatgt aatatggtag ataaaattta ttataaattt tattaaggga
    52081 gtttattata atgggaaaaa tcaatgttat aaagactaaa atagaaggat tatatatagt
    52141 cgaaccaaat gtattttatg atgaaagagg atattttatg gaaagctata ataaaaagga
    52201 ttttatagag cagggtcttg atatgtgttt tattcaagat aatgagtcta gctcaagaaa
    52261 aggcgtttta agaggaatgc attttcaggt taaatatcct caaggaaaat tagtcagagt
    52321 tacagaggga gaagttttcg atgttgcagt tgatttaagg aaagattcac aaacatttgg
    52381 gaaatgggaa ggtgtaatat tgtctgataa gaataaaaaa caattttata ttccagaagg
    52441 gtttgcacat ggatttttag ttttatcaga aaaagcagta tttagttaca aatgtacaaa
    52501 ttattattac ccagaatttg agaatggctt tatatggaat gacaagcaaa tatctattga
    52561 gtggccttta aaaggaattg aagaaatatt tttatcagaa aaggacaaaa aacaaaaaag
    52621 ttttaaagat atttgtacaa gacgttaata aaaatttatt agaattaaca tttaggagaa
    52681 aaaatatgaa aaaaatactg ataactggag gagcaggatt tattgggagt aattttatac
    52741 attatatgct taacaagtat gtagattatt ttattgttaa cctagacttg ttgacttatg
    52801 ctggtaattt agagacatta atagaaatac aagacaattc caattataaa tttgttaaag
    52861 gagatatttc aaatagggag caggtgtata agctatttga agaagaaagg tttgatatag
    52921 ttgttaactt tgccgctgaa tctcatgtag ataggtcagt tgagaatcct gatttattta
    52981 ttaaaacaaa cattatagga acacaagtac ttttagatgc atctataaaa tatggagtta
    53041 aaaggtatca tcaaatatct acagacgaag tgtatggtga tttaccaatt gatagaaagg
    53101 atttattctt tacagaacaa tcttctatca atccaagttc tccatattca gcttctaaag
    53161 catcagcaga tttattggta agttcttatt atagaacata tggattgtta acaactatat
    53221 ctaggtgttc caacaattat gggccatatc attttcctga aaaattgatt cctcttatga
    53281 ttttaaatgc tttggaaaac aaacaattgc cagtatatgg gaatggggaa aatgtaagag
    53341 attggttaca tgtatatgac cattgtactg ctatagactt aataatacat aaaggaaata
    53401 taggggagat ttacaatata ggaggtcata atgaaagaag taatctagaa gtagtaaaaa
    53461 tgatattaaa tcttttaggt aaatctgaag agttaatatc ctatgtaaat gatagacctg
    53521 gtcatgattt aagatatgct attgatgcaa ctaaaataga gaatgagtta ggttggaagg
    53581 caaaatatga ctttgatttg ggtataaaag aaactgttaa gtggtatata gaaaatgaat
    53641 cttggtggaa agctgtttta tcagtataac tttaaaattt agaaaggggc gttttatatt
    53701 gaatgagata agttcactaa ttaatatatt agcattgact caattatctg gtagtaatac
    53761 tacaaatcaa tgtaattgta catataataa ttcatctgga tttgatatga ttatgatgac
    53821 cttgttaaaa gcattatcac aaaataatca acatacttct aatagctaca atttattgtc
    53881 taattctgag aatttattta atgaacttga taatgtagta aataatacca ctagtagatt
    53941 tatagatgtt gatacaaaag ataaaaatgt aaagttgaga attgaaaatg ctgtagatca
    54001 agcatcaaaa aaatataacg tagattcaaa tcttataaaa gcaataatta aagttgaatc
    54061 agattttaat ccaaataccg tttcttctgc tggtgctaag ggtcttatgc aacttatgcc
    54121 agaaaactgc agagacttag gagttacaga cccttttaat atagaacaga atatagatgc
    54181 tggaactaga catattaagg aatacattga tatgtttgga gggagcatag aaatgggatt
    54241 gatggcatat aatggtggtc ctggaagaat gaaaagtaga ggagtagaat caatctctga
    54301 cctgtataaa atgccaaaag aaacacaaaa ttatattcct aaggttatga aatattatag
    54361 agggtaggct ttattatggg aataaatata gataagctaa acataagtcc aagtataaat
    54421 atggaggtta aaaaactaaa agagagtaat aaattttctg acaaattaaa ctctttaaaa
    54481 caatcttctt cattggaaga tataaaacga aatttggaaa gtgtaaaaaa ggcaggagaa
    54541 aggcttgtac ttactcaaaa ctatggcgat attagtatat ataaaaatgc agtaaaagaa
    54601 tacctaaaat ctgttgtaga taatatgtat tcacttgata aaaatagtag cttttgggag
    54661 catcagtatt ataagaatgt aaagattgtt gatagtaaac ttgaggatat gactagtaag
    54721 ttaattagtg aagaaaaaga aaacatagat attgtttcta ctgttgacat gatacaaggc
    54781 ttattgatag atatgtatag ataaggttat acaaggagaa aaattttatg aatagcaaaa
    54841 aagaggatat atatgaattg aattttgggc aattaataga agaaaaatct ggtgttatag
    54901 aagaaaatca aaatgttttt aatgcaaaag taaatgtagc tgtttctata ggaaatacaa
    54961 cagaaacaat aaaaaatata ttagatttaa aagaaggctc tataataaaa ttaagtaaga
    55021 atgtggatga aaaattagat atatatgcaa acgatagatt gtttgcttat ggagaaagca
    55081 ttattacaaa tgagaggtta tctgtaagat tatctaaaat agaagatcca gatgtaaatt
    55141 agcattttaa atagtatccc tttaggctat tctgtatgag tttagctaag gggatatttt
    55201 tataaaaaat ttaaaatatg tgtgaattat ataaatattt ttattttatg agcgataact
    55261 aaattataag tatgtaattt tggaggtgaa actatggata ttaaaaatgt aagttcaaat
    55321 attgtagtga ataattattt aaagaataca tctggtataa aaaaagtgga agaggttaaa
    55381 aaaattaata aaacagataa gatagagtta tctaaatttg caaaggaaat ggcaagtgtg
    55441 tcaaatatga gtgatgagaa tattagaaat aaaaaagtcg atgaaataaa aaatgcatta
    55501 gaaaatggaa cttacaaaat aaaaccaaaa gaaattgcga aaaaaatgat agaggatatg
    55561 cgaggataaa gtcatgatta cagacttaaa agttataata tatgaagaaa aaaatataat
    55621 tagtaagatg atggaattat taaaagaaca atttgattat atagttgaaa aagacttaga
    55681 aaatttaaat atgttaaatc ctaaactaga agatattagc agggagcttg catccataga
    55741 aataaagaga agacaacttt ttggtgatga tatttcaatg agtgaagttg ttgaaaatag
    55801 taatgatgga tacttaaaag aaatatatac agacttgaaa cacattcttg ctttagctaa
    55861 aaatcaacaa gaatcaaatg attctctaat aaagaaagaa cttattttta cgaaaaaaat
    55921 gattaatttc ataaaaccag ctgataagca aactacaact tataattctt atggaaatat
    55981 tagaaaataa atattaggag gagaaatatg gcaggattat tttccatttt aaatacagct
    56041 aattcaggaa tgaatgcgca ccaaaaagca atacagacaa tttctcataa tataagtaat
    56101 ctagatacag acggttattc taggcaaagg accgagtttg ccacaaatag tccaatgtat
    56161 atgcctagtt tgagtaattc aattgcaaga ggacaattag ggactggagt acatgtaacg
    56221 gatgtaacaa gagctagaaa tagtttttat gattaccaat ttagggcaga agctcataag
    56281 tatggtaaga cagtttcaaa atatgattat tacaatacta tagaaactat actaaatgaa
    56341 ccatcagact atggaatatc tgcaggtata gatgattttt ttaaaggatg ggagtcatta
    56401 tcaaaggata taaatagtga cagtaaaaaa agtctagtgg tagaaaacgc atctaattta
    56461 gcaactttaa taagtgaaag ttataagaag cttgataagt taaaagaaga tatagattct
    56521 aatatagaca ctgagataaa acaaataaat gacatgttaa aaagtcttga agatttaaat
    56581 aaatctattg atattatatc tggttctggc tctacaccaa atgatttact tgatgaaaga
    56641 gatagaattt tagataactt gagttttaaa ctagactttg aaaatagtga tgttaaaaat
    56701 atgcttgcag atggtaaatt agaacttaat gaattaaaaa atccagatgg aacttggaaa
    56761 acaggtatat cagggacctt acaaggcttg tttgaaatgc atggtaagat tgatacatat
    56821 aaaagcgatt taaaagatgt atctgatgga ttagctaaac agataaatga tgtttataat
    56881 acgtctgcag gaataacagt aacagatttt tttataactt caaatgtaga tggtgaagat
    56941 attataaaga taaatccagc tataaagagt aacccaaatg aattaaagct tactgctgat
    57001 gaagcttcaa aaattgctaa gttaaaggat gaaaaaatag atattggggt ggctggtgga
    57061 aaagtaagta caataagtga ccactataaa gcctttgcag aatcaatcgg tttagattct
    57121 caaaaagtaa atcaagatga agcaaatcaa cgtaaaatta taaataatat tgataactca
    57181 agaatgagtg tttcaggtgt atctttggat gaagaaatga cagagcttat aaaaatacaa
    57241 cgttcatatc aagctagtgc aaaagttatg tcaacagctg tgcaactact ggatgttgta
    57301 ataaatggaa taatttaata gaagggggaa tttataatga gagtcagtac aggtatgatg
    57361 tctagcagct atctaaactc actacaagat aatctacaaa gattggataa ggttaataga
    57421 caagttaata caacaaaaga aataaacaag ctatcagata atccatataa agcaataaag
    57481 atattaaact caaaaagtga aataaagact atggagactt atgttgagaa ttgtaaagat
    57541 acagggaatt ggttagaaac tactgatact gcattagatc agcttggaaa attattatca
    57601 gacataaaga aaactttggt ggcaagtggt gatggtgcat actcagatga tgaattaaag
    57661 actcttagta atgaaactaa tgaaaaaatg aaagaaattg caaatgcttt aaatgcaaca
    57721 catgaaggga agtacatatt ttcaggttca aatacggggg taccacctgt tgaatgtata
    57781 gataatgctg atggttcagt gagtttaaag tttaattcta gtctaaatct taataaatta
    57841 aatgactctt tgagtatgga tatagctcaa ggaataagtg tagattataa cgttaaattg
    57901 agtagccttg gatttgaccc aacaaaaact gacccatttg aagagttaaa taacatatca
    57961 aaaaaattag caaatccaga tgctgatgct ataaaagagc ttacaacaac ttgtttgggc
    58021 gatatggaac aactaataga aaatacagta aatgttaggt ctatatatgg gacaaaagca
    58081 aatacagtag aggctatgaa ggaaaaaaac gatgatagtt tgatacagtt aaaggatatt
    58141 ttgtcacaaa atgaagaaat agattatggt gaaaaacttg ttcaattaaa ggcagcagag
    58201 ttaacttatc aagcttcact acaaacagga ggaaagttat ttaatgtatc tatattagat
    58261 tacatataat aaaataacgc agatatgatg aaggttacat taaaaaaagg tatattaggt
    58321 tttgaaaatt taaaagaata tgagctttta gatatagaag ataatgatta tttaaaagaa
    58381 tttaattcta ctgaagaaga aggtatagga tttgttgttg tatctccatt tgagattatc
    58441 aatgaatatg aaatagtttt aaatcaggaa acaatagaaa aactagaagt gaaatctcca
    58501 aaggatgttg tattatttaa tataattact cttggtcaga catttgaaga atcaactgtg
    58561 aacatgaaag ctcctatagt gataaatata aaaactaatt ttggaatgca aataatttta
    58621 caggatgata aatattcaat aaggcatcca ttattgagag gtgatagtgg atgctagtaa
    58681 tttcaagaaa aaaagatgaa gcagtactta taggagaaag catagaagta aaaattgtag
    58741 gggtagatgg aaacaatgtg aaactagcta tatcagcgcc taacaatata agtatattaa
    58801 gaaaagaaat atacgaaaaa gtaaagagtg agaatataaa agctacaaat aaaaatataa
    58861 aaattttaaa gtcattaaaa taataagctt ggaggaagta atatatgtat ggagaaaatc
    58921 cttataattc ttataaacaa aatgctgttt ttatggcatc aaaggaacaa ttgttactta
    58981 tgcttgttga tggagcagta aaatatacca aaatagccaa aacagctatc ttagataaaa
    59041 atacacaaaa agcgcataga gagcttataa gagttcagga tatatttaca gaactaatgg
    59101 ttacattaga ccaaaatgca ggtcaatggg caaaggatat gtacagagtt tatgattttg
    59161 taagatatga actttcaaga gctaatatta gaaaagacat tcaaataata gataatgtgt
    59221 tgcctgtaat agaacaaatt aaagatactt ggcatgaagc tgataaaaaa agtaaagaag
    59281 aaagaagtag gtacaaataa tggaattaaa tttagctgaa ttagataagt tatcaaaaga
    59341 ggaattacta ttgatgcttg tagatggaac agtaaaatat accaatatat ccaaagaagc
    59401 tcttttaaat aacgactatt tgaaagcaca taatgaactt gtaagagttc aaaatatatt
    59461 tacagaacta atgactacat tagaccaaga tgcaggtcaa tgggcaaagg atatgtataa
    59521 agtttatgaa tttataaaat ctgaattagc aatagctgat gaaaataaag atattaaaat
    59581 aattgatgat atattgccaa tagtaaaaca aattagagat acatggcatg aagtttacaa
    59641 tcaactaaaa atataattgg atggagggat aaaggtatgt caagtataag tcctataaga
    59701 gttacaggtc tttcaggaaa ttttgatatg gaaggcataa tcgaagctag tatgattaga
    59761 gacaaggaaa aagttgataa agcaaaacaa gaacaacaaa tcgttaaatg gaagcaagaa
    59821 atatatagaa atgttataca agaatcaaaa gatctttatg ataaatatct aagcgtaaat
    59881 tctcctaata gtatagtaag tgaaaaagca tactcttcta caagaataac cagttctgat
    59941 gaaagtatta tagtagcaaa aggctcagct ggtgcagaaa aaataaatta tcaatttgca
    60001 gtttctcaaa tggctgaacc agcaaaattt actattaaat taaattcaag tgaacctatt
    60061 gttcaacagt ttcctccaaa tgctagtgga gcgagttctt taactatagg agatgtaaat
    60121 ataccaatat ctgaacaaga tactacaagt actattgtaa gtaagataaa ctccctttgc
    60181 gcagataatg atataaaggc ttcttatagt gagatgacag gtgaattgat tatttcaaga
    60241 aaacagactg gttcgtcatc agacattaat ttaagagtaa ttggaaatga caatttagct
    60301 cagcaaattg ctaatgataa tggtatcaca tttataaatg atgctggtgg aaacaaagtg
    60361 gcaaatgtat atggaaagaa tctagaagct gatgtaactg atgaacatgg aagagtaact
    60421 catataagta aagaacaaaa ttcatttaat atagataata ttgactataa tgtaaattca
    60481 aaaggaactg caaagttgac ttctgtcact gatactgaag aagctgttaa aaatatgcaa
    60541 gcatttgtgg atgattataa taaactgatg gacaaggtct atggtttagt tactactaaa
    60601 aaaccaaaag attatccgcc tcttacagat gcccaaaaag aagatatgac aactgaagaa
    60661 atagaaaaat gggaaaagaa agctaaagaa ggtatactta gaaatgatga tgagttaaga
    60721 ggttttgttg aagatattca atctgcattt tttggagatg gaaaaaatat tattgcatta
    60781 agaaaactag gtatcaatga aagtgaaaat tacaataaaa aaggtcaaat atcatttaat
    60841 gcagatactt tttcaaaggc tcttatagat gatagtgata aggtatacaa aacactagca
    60901 ggttattctt cgaattatga tgataaggga atgtttgaaa agctaaaaga tattgtatat
    60961 gaatattctg gaagttcaac ttctaaactt cctaaaaaag caggtataga aaaaactgct
    61021 tctgctagtg aaaatgtata ttcaaaacaa attgcagagc aagaaagaaa tataagcagg
    61081 ttagttgaaa aaatgaatga taaagagaaa agactttatg ctaaatattc agccttagaa
    61141 tctttgttga atcagtattc ttcccaaatg aattatttct cacaagcaca gggtaattaa
    61201 ttatggataa attaaaagaa aaattaaatt tatataaaga tatatcttta caaattataa
    61261 atttgattga aaaggaagaa tatataaaga taagtattaa gttaggtgaa agacaagaga
    61321 ttataaatag tgtaagtgaa attgatagaa atgattttat acagctttat aatagaatgg
    61381 aattaattga aattgatagc aggataagag atattttaca aggacaatta ttagaagtaa
    61441 aaaaagaatt acatgagtat aagcttacta aacaagtgaa cacaatgtat tataacttaa
    61501 atagagaaaa agtaaatatt tttaataaaa aagtataaag ttatgtacca tcttgtccga
    61561 ttatataaat gaagaattaa taaaaaagat taaaagtaga aatgacaagg atgtcaacta
    61621 tactaaggag ggtaaaataa tgagagttaa tacaaatgta agtgctttga tagcaaataa
    61681 ccaaatggga agaaacgtaa atgcacaaag taagtctatg gagaagctat cttctggtgt
    61741 tagaattaag agagctgctg acgatgctgc tgggcttgct atatctgaga aaatgagagc
    61801 tcaaataaaa ggtttagacc aagcaggaag aaacgttcaa gatggtatat ctgttgtaca
    61861 aacagcagaa ggtgcattag aagaaactgg taacatacta caaagaatga gaactttatc
    61921 agtacaatct tcaaatgaaa ctaatactgc tgaagaaaga caaaagatag ctgatgagtt
    61981 actacaatta aaagatgaag ttgaaagaat atcaagctca attgagttta atggtaagaa
    62041 attacttgat ggaagttcta cagaaataag attacaagtt ggagcaaact ttggaacaaa
    62101 tgttgcagga acatctaaca acaacaatga aataaaagtt gctctagtaa atacttcaag
    62161 tataatgagt aaagcaggta taacaagttc tacaatagca agcttaaatg cagatggaac
    62221 ttctggaaca aatgcagcta aacaaatggt atctagctta gatgtagctc ttaaagaatt
    62281 aaatacatca agagcaaaat taggggcaca acaaaataga ctagaatcaa ctcaaaacaa
    62341 cttaaataat actatagaaa atgttacagc agctgaatca agaataagag atacagatgt
    62401 tgcttcagaa atggttaact tatctaaaat gaatatatta gttcaagcat cacagtcaat
    62461 gcttgctcaa gctaatcaac aaccacaagg agttttacaa ttattaggat aaaataattt
    62521 tgtatattgg atatagaaga aagggtaagg ctttgcttta ctcctttctt tttttacaaa
    62581 tatacttttg aaaggaaaat ttatatgtta cttagtatag ttatgattgt taaaaatgaa
    62641 gaaaaaatac ttgaaaaaac tttaaaatca ttaaccacat taagaaattc tatagaaagt
    62701 gaacttataa tagtcgatac aggttctaca gatgatacta taaaaatatc taagaagtac
    62761 acggaaaaag tgtattttca taattggaat aatgattttt ctagtatgag aaatatatca
    62821 atatcctatg ctaaaggtga atggttactt atattagatg cagatgaaat actaattgat
    62881 tcttcaacta ttgtaaaatt ttttaaagat ggtcttgata aaaaatttaa ttctgcttca
    62941 atacaattaa aaaatcttta ctcatatgat aaaaaattat atggatattg ttcagtgctt
    63001 agacttttta aaaacgttga ttttagatac catggtaaag tacatgaaca accaatatac
    63061 aaaaacccta tatttaataa tgttgctgat tttgaacatt atggatattt gtttgaagat
    63121 gaagaaataa gattaaataa ggtgaaaaga aatgaaaaac tattatttca agagttaaaa
    63181 gagaatgata attctccata tacaaactat caattaggga aaaattttat tatattagga
    63241 aaatatcagg aggctttata ctatcttgag aaatcttatg aattatattc taaactagaa
    63301 ttggcacctg gttacttgat aacaagcctt gtaaaaacat atttatattt aggaaaacat
    63361 aagaagtgtg aaagattgtg cttaaagtat attaagaaag acatgaataa tattgatata
    63421 tattattata ttgcacaagc acaagtagat ttaggaaagt atgaaaatag tatagattcg
    63481 tataagagat atatttactt gttagataat tatgaaataa gtacacaagc aaatagttta
    63541 ttttcagaca ctgatactgt agggcttaga gatgaggcta ttattacact gataaagatt
    63601 tattataagc ttgaaaaata tgagtttgta atttcagagt ataataacat tgaagatgtg
    63661 gaaaagaaaa agaatgtgta ctttagctta tttatgtcac tatataaatt gaatagattt
    63721 gaagatataa aaaattatta taaagaagtt tcaaattcta aaattgaaaa aaatagtttt
    63781 tatagaaata tagaagaagt tataaataat attaaagagg atgaaaaaga gtatgtatat
    63841 aaaatccttt gtgacattga aggtaattat ggcattttaa atcaaataag gataaataaa
    63901 tgtgtatcta tagataaatg taaagaaata ctcaatgaag aaaaggaaat aatttatgca
    63961 tatattataa aaatagcttt tgaagagaag attgatttac tagatatttt ttatgaaatg
    64021 gaatatgtat ggatagagaa atatctaaaa tatcttttag cattagaaag aagttttaat
    64081 ttagtactat ataagtacat aattagtcgt ccaaatacat cagatatgga aaagataaga
    64141 gtatataaag ctatatctaa agtagtttta gaaagtataa gcttaagtga tgaaaaatat
    64201 aaggagattt tttatcttta tataatgtat tcttataagt acataagata catatatagc
    64261 aatttaagtg attttgaatt aataaaattt gtttgtaatg atttagataa gttcactata
    64321 gaatttaagc atctacttga tattaaaaat aaagtaaata atgctaatga aaaattagag
    64381 tatatacata gtatgaggaa attactaaat gagtatcctt tttataataa aataataaaa
    64441 atacttatag gtgaattaga agaaaatata aaagaaagtg aagaatttaa ggatttaaaa
    64501 gatagtttta ttattagtat agaaaatatg attgaaactg gcaaaataaa tgatgcgaaa
    64561 ttattggtag atgactattc aaaaacattt gtggatgata taaagatttt aaatataaag
    64621 ggaattttat acatgtttga aaataagctt gataaagctg attttatgtt aaaaaaggca
    64681 ttatcattag atgtagaaaa tgaagatact atatataata tagaatactt aaaaagttta
    64741 agataagtca aaaataggag aattgaagaa tgaatatacc aatagtggtt aatgaaaaat
    64801 ctaaagacat aataaaagat tggcaatata catgtacaaa tgaagatata aaatttacaa
    64861 gcataataat attgacatat aatcaaatag aatatactaa attatgtatt gaaagtatta
    64921 ggaaatttac cccaaagaat aaatatgaaa taataataat tgataataac tcttctgatg
    64981 gaacagttga gtggttaaag ggacaatctg atataaaatc tgtgtataat aacaaaaact
    65041 taggatttcc aaaaggatgc aatcaaggta ttgagttagc tactggtgaa aacatattgt
    65101 tgttaaataa tgatgtaata gttactccaa attggctcta taatttgaat aaagctttat
    65161 ggtctcaaga taatataggt gctgtaggac ctattacgaa tgcatgttca tattatcagc
    65221 aaattgatgt tgattataag tcaattgagg acatgtttat atttgcacac aaaataaata
    65281 aatctaatat taacctatgg aaatatagat tgaagttagt tggattttgc atgttaataa
    65341 aaaaaactgt tctggataat gtaggggttt tagatgaatt attcacacct ggaaattttg
    65401 aagatgatga tttatctttt aggatgatag agtcaggata taagttatta ttatgccagg
    65461 atacttttat acaccatttt ggaagtgtgt cttttaaaga aaatcgtaat aaatatacag
    65521 atataatgta tattaataga agaaaatttg aaactaagtg gggatttaat ccagaatata
    65581 gtggaatgat aagaacagat ttgatttcta aaatagatga tagtttggag gcaaatatta
    65641 atgttttaga aataggatgc ggtatagggg ctactctttt agaaataaaa aatatatata
    65701 aaaatgcatc aatatatgga atagaaatta gtgagtcagc aggtaaactt gcaaagtata
    65761 gtgcagatgt acttatagca aatatagaaa aagtaaaatt ggattataaa aaagattttt
    65821 ttgattatat aatattggga gatgtacttg aacatttgat tgacccatgg aagatagtca
    65881 atgaattgaa acaatatcta aagaaggatg gttatctggt atctagtata ccaaatatta
    65941 tgcatgtttc tgttttaaga aatcttgtgt taggtaattt tacatatgaa gattcaggaa
    66001 ttttggacaa gactcattta aggtttttta cattaaatga gataacaaaa atgtttaatg
    66061 atagtaatta cataattaat agtattacag ctactagtat gccactttcg gaaattgata
    66121 atagcttcat tgatacaata tgtaaggaaa gctgtaaaga aatgagacaa cagtacgaat
    66181 cttatcaata tatagtaaaa gcctctaaaa tcctagatac taaaagatat tctagtatta
    66241 gtatgattaa tttaaaatac gctttaatga gaattgataa tgaattagat gtagatagta
    66301 atttaagtta tatatttgat aattataata taactgaacc atgttttgtt gatgatattg
    66361 aatatctaat tgatacattt gtgataaata aagcaactct attaaataga ttaggagttg
    66421 aggcatttaa cagaggtcta ggagatttta gtataaacat gtttatgaca gtattagaga
    66481 tggatagaga tgatattgac tcaatatata atataacaag tgtattatgt gaattagaag
    66541 aatttgatac tgcttataat ttaattaaaa atagtagcga aaaagtacag agtgaaagtg
    66601 atatacaaga gatactttgt tttattgagg ggaagaaata tgaataatga taagatatgt
    66661 tttataacct gtgtaaatga tgaaaggctt tatgaagaat gtcttgtata tataaatagc
    66721 ctagacattc ctaaaaactt tagtatagaa acagtagctt taagaggagc cgattctatt
    66781 gcctctgctt ataataaagc tatgagagaa acagattcta agtataaggt atacttacat
    66841 caagatactt ttataattaa taaaaatttc atacatgata ttttagagat atttaaaaaa
    66901 aatacagatg tcggaatgat tggtgtagct ggagtaaaag atatgcctgt gaatggaatt
    66961 tggtgggatt ctgataaaaa agcagggaaa gtatatgata gtcatacagg taaaatggat
    67021 atttatgaat ttagtaactt tgaagaatgt tttaatgaag ttatggctat agatggatta
    67081 attatgatta ctcaatatga tgtattttgg agagaggata agtttgatgg gtggcatttt
    67141 tatgatttgt cacagagtat ggagtttaga caaaataaat acaaagttat tgtaccaaaa
    67201 caaaataagc cttggtgtat gcatgattct ggagtagtaa atataaataa tggatatgat
    67261 gaatatagga taaaatttgt aaaagagtac ataaatcttg atttatatag agaaaatttt
    67321 tatgaatttg ataagaagaa agcaagtacc atacttaaga gtaataagca tgtaatggat
    67381 tgtatgaaag aggagcttac agaacaatta agattaaaga attacaagga tgttttaggt
    67441 attgtttcta aaattgctca tttttctgtt tttaatcata ctggtttgta ttcttgtgaa
    67501 gaatgtgaga gagcattgct agaatgtgca aataatttac cagaaataga aaatacgaaa
    67561 ttatttacaa aaaaagattt aaaaagaaga aaagtattac atgttttaag tgaaggatat
    67621 tcaacaggag gtcatacaag actagttaaa aattggattg aaattgacaa agactctgtt
    67681 cattcagttg taactacatg gcaatcagat acactgccag actggttatt aaaagcaata
    67741 aatgatagtg gtggcgaagt tatatctttg gatttaattt cagatgatta tttaaaaaga
    67801 gctgtagctt tgaggaaaat agcttatgac tgggctgata tagttatttt atatgttcat
    67861 atgtgggata caatacctgt tgttgctttt ggagttgatg ggaaaatacc tattttacat
    67921 gttaatcact atgatagtac tttttggtta gggacaagta ttgcagatat tgtcattgat
    67981 tttagcgaaa ctagtcaatt aattacatta gataaaagag gcatagataa atctgaaata
    68041 ttaccaatgc cattaaaaga aaaagaagta ttttcaaaat ctgaagttag aaaacgatat
    68101 aatttagagg atgatgtgac aataatattg actattgcta gtgaaagaaa atacaatagt
    68161 gtaaatgata ttaattactt taaaattgct aaaacattga ttgaaaatac agataataca
    68221 attattattg ttgtaggagt tgatacagag aatctctatt ggaaaacttt aagtaatgtt
    68281 acagataata gagttatatg ttttggaaca acagcaaata tagatgattt ttataagatt
    68341 tcggatatat acctagagtc tttcatggta ggaagtcata cttcaaaatt agatgcaatt
    68401 ttatatgatt taattcctgt taagtttaaa aatgaagttt caccaatttt tacaaatatg
    68461 tggaatttta tagataagtt tgattataag aatataaaag aggttataga catgataaga
    68521 aggtacaata ctagtgaatt tgacagggat aagataaaag caaaacaatc ggaaataaaa
    68581 cattttgtta tagataaaca ttgtattgaa ataaaaaact atatagacaa aatatataat
    68641 gaagttaatc atcataaagt taagtatgat ttatataaaa atgatgaaat cgaggactat
    68701 cagctttttg tagcattata tggctatatg gtaaaaaata aaaacatgtc ataggtggta
    68761 aaatgaacaa tattcatatc aataaatttg aaaaaagctg tgaaaaaaac tgggattatt
    68821 ttgtagaaaa taaatctata aatggtacat ttctgcaaac tagaaatttc cttaattatc
    68881 atgaggaggg aaaattcact gaccactcat taataatatg taaaggtgaa gaaatactag
    68941 cagtcgtacc tgcatgtgaa acttatgaag atggtgaaag aatatttttt tctcatttag
    69001 ggagtacttt tggtggcatt ataataagaa gtggttttaa tgatattagg catgtaaatg
    69061 ccattacaaa taagttagaa atatatttac aggaacaaaa tttcgataaa gtatatttaa
    69121 aaaatacatc aagaatattt tgtaaagagg atacttcatt actagaatat tttttattta
    69181 agaataatta catgttttat gatgaattaa gtatgttttt agaattaagt aagtataaag
    69241 aagatatatt agccaatttt aaatacagta aaagaagaga ttttaaatat tctttgaaga
    69301 ataatcttac ctttaaaaga ctgtatagtg atgaagatat agtttgtttt tttaatttac
    69361 tttctaattg tttagatagt aaaggagcta aagtaataca ttcagtagaa gaacttttgg
    69421 agtttaaaaa taatagatta aaagatattg tagaatttta tgcagtatat attgatgaca
    69481 ttatgatttg tgggagcatg gtatttaact ttcaagaaag agtttatcat actcaatatc
    69541 tagcatcaaa ttcgacatat aataaatatt atccaatgat atttttatac tataatctaa
    69601 taaaagatgc tttagagaga aattttaagt atctttcttt tggaattagc actctaaata
    69661 gaggcaaata cttagatgag ggtttagcta catttaaaga aggttttggt tcaagtgcaa
    69721 tttgtaacag aacatactat aaaaatataa ataagtgaga atcatgtttt atagagtttt
    69781 tagagtatag taaatatcta gtactataat attacataaa aataattagt ttataaagaa
    69841 ggtttgtata tgaaaagatt aatgatttta ggctcaatta agtattttga gaatattgtt
    69901 atgtcagcta aaagagaggg aatatacaca attgtttgtg ataatagaat tgatactcct
    69961 gcgaaaaaga tttgtgatga agcaatagat gttgatgtat ttgattttga taaaataaag
    70021 aatatagcta tagataaaaa gatagatgga attttaactg gatttacaga ttctttaatg
    70081 aagccatatg tttatattgc aaatgaacta aatttgccat gtgtgatttc ttgcaatcaa
    70141 cttgaatctg taactaataa ggctgttatg aaaaattatt ttaaaaataa tggaatacct
    70201 acaactgatt attgtattat tgaaagtttg aaagatttag aaaaaataca aggattaaat
    70261 tttccacttg taataaaacc tgttgatggt tatggttcaa gaggtgtata ttttgtatca
    70321 aacatagaag aattaataga aaaatttgaa tattctaagg aagcctcgca agatggacaa
    70381 gtaataattg aggaatttta tgaaagtgag gaaatacaag gactagcttg ggttcataat
    70441 ggagagtcac atgtatttta tattggagat agagagcttg taaatataca tacaggaaga
    70501 gctggaaaac cagatagatt aatttatcca tcaaagtatt gttttcaata tgaagaagaa
    70561 ataaaatcca tatatcaaaa tataacgcag gcttttggca taaaaaatgg acctctttat
    70621 gtacaaatgt tagtgggagc atatggaata aaggtatctg aagtaatgcc aagattacct
    70681 ggaggttgtg actatatggc tatttctcaa ataacagatt tagacatagg aagtttattt
    70741 gcaaacttta gtgtgaataa tgaagtaaat tttgatgaaa taaagaaata taatatgcat
    70801 ctatcaaaat gtgtatatgc attaccaata tacataagac ctggcacaat aaaaaagata
    70861 aataatatag ataaaataga aaacttagat tatgtcactc aatttctatt actagtaaaa
    70921 gaaggagata caataggatt atatgaagat gagagacagg attgtggaag agtttatgga
    70981 gtagcaaata atgtatttga tgcaaatata aagaagaaat gtattcatga aatgatagaa
    71041 atacttgatg aaaataatga aaatatgata gaaaattttt aaataaggga gtatgataga
    71101 tatgaagcta ataactcatg aacaaattat gtcattaaac atttctcaga aacaaggata
    71161 cgagtggata aaagaatcct ttttaacaaa aaaagattgt caattaccac caaaaataag
    71221 catggtagaa gaagggcatg tattttacaa tgtaatgccg tccctaaatc ataatcataa
    71281 gattggtgga ataaaaatgg ttacaagatt gccagggaga aatccaagtt taaattcaga
    71341 gatatttcta tataatatgg aagatgctaa attaaaggct attttagatg gcaattatat
    71401 tacagctttt aggactgctg ctgttgctgc cttggctatc gatacatttg ctaaaaaaga
    71461 ttttaatact attgctatta tgggtttagg tgtaactgct tctgctataa tgaatatgct
    71521 ttcatatact cttaaagata aaaatataaa tataaagtta cttaaatata aagaccaagc
    71581 agagtcgttt gtaaaaaagt atgaaaaaaa tgaacaattt agttttgaaa tatgtgacac
    71641 acatgaagaa cttattgtag attcagatgt agttatttct actgtgacat atacagatga
    71701 atatttatca gaatttaaat ggtttaaaaa aggtgcttta ttattacctg tacatgttat
    71761 gggatttgga aatgttgatt atctatttga taaagtatat ttggatgatt ataatcattt
    71821 gaaacatcta gaaaatatag atagatataa atattcttgt gaattttatg atgttttaag
    71881 taaacaagct aaaggaagag aaaatgatga tgagagaata atatcttaca atataggttt
    71941 gtcaatacat gatatattat ttgcaaataa aatttacgaa ttgtgtgaaa cactaagctg
    72001 tgaagaaata gaattaaaag aaccaaaaga aaaatattgg atatagttta tttcattcat
    72061 atttacaata gtttattgta aatatgaata tgaagtaata tattgttaga aaattagcat
    72121 gaataggata gataaattta tggataaata taatttaatt aggttcgtat ctattggaaa
    72181 cgaatatata ggaaatttag ttgcattaga atcaaataaa gcaatacctt ttgatataaa
    72241 gagagtttat tacatatatg atgtaccaaa caatgtaaag agaggatttc atgcacacaa
    72301 aaacttggaa caagtactag tttgcctaaa tggaagtgtg aagataaaat gttatgatgg
    72361 tgtaaaagag actatattta atttacataa aaatgatgtt ggattatata taggaacggg
    72421 agtgtggcat gagatgtttg attttgatga aaaaactgtt ttaatttcta tagcatctga
    72481 acattataat gaagaagatt atattagaga ctataaagaa tttttaaagt atttaaataa
    72541 tgtgtagtta ttatacaatt agtgatgtat tttcttaatt aaataaattt aagatagcca
    72601 catagagaat agatagatta ggatgtgaat ttattgttgg ttaaatttaa taatttatta
    72661 aaacagttcc aaactcataa agaagaatat gaacagaaga ttaaggatgt aatggaaagt
    72721 ggatattata tccttggaaa tgaagtaaag cattttgaag aagaatttgc taactatgta
    72781 ggtagcaaat attgtgttgg tttagccagt ggtttagatg cactgataat tgcttttaga
    72841 gcattaggaa taagcaaagg tgatgaagta atcgtgcaat caaatacata tattgctagt
    72901 gttatgggaa tcagtataaa tggagcaaca ccagtatttg tagaaccaaa tgaatattat
    72961 aatatagatt catctaagat agaagaaaag ataaatagca aaacaaaagc tatattagta
    73021 gtgcatttat atggtcaagc aagtaatatg aaagatatac aagaattatg tgataagtat
    73081 aacttgtatt taattgaaga ttgtgctcaa tctcatggag ctaaatatga tggaaaaatg
    73141 acaggaacat ttggtgatat aggttgtttt agtttttatc caagtaaaaa tttgggtgca
    73201 tttggagatg caggagctat agtaactagt aatgaggaaa tagctgataa agtgaaaatt
    73261 cttagaaact atggctcaga aaagcgatat tataataaat ttgtcggata taattcaaga
    73321 ttggacgaaa ttcaggcagg tttattaaga gtaaaactta aatatctaaa tgaaattgaa
    73381 attgaaaaat caaaaatcgt agatagatat cttaatgaaa ttaataatcc caaagtcata
    73441 cttccaaaga tagaaaataa ttgtactcat gtatggcatt tatttgtttt acaagttgaa
    73501 aaacgagata catttatgga atacttaaag aaaagtggta tagagtctat aatacattat
    73561 ccgataccac cacatctatc tgaagcatat gcttatttgg gatataaaaa ggggagtttt
    73621 aatatagctg agaactattc agataaagtt gttagtatac ctttatttat tggtatggaa
    73681 gatgaagaag ttagttatat aattaaaatt ataaatgaat attaaactac tcataataat
    73741 atcaaaaata aattttttat atatcattta tttaaatttc gttaattgac atttttaaat
    73801 attgatatat tgtacaaata aaattgaaat atatggaaaa atatagaatt aagatgagat
    73861 ttgtcttata tttttataaa ttaaaaatat tttcaaagag tttattataa aattgtaaac
    73921 tatagtgttt ataatctttg taattattgg taattaaatt taaaaaataa aatatttaat
    73981 tatacacaaa aaagatattt aaaaaatttg ttatttattg tatacttaag ttaaaactaa
    74041 ataggcaaat ctagagaaat ctagtgacgc aaagctatag ggactaaggt ttatatacat
    74101 aaactatgtc agccagttgc caaaaagagt cctaggtgta ttgtatacct aagaaaagtc
    74161 tataatgact gcctttttgg cagtcatttt gttatggaaa aatcacttta tttcagtaga
    74221 aaatacacat aataacatat tttaccaatt ataacataaa ataaagaaaa attatctcaa
    74281 aaagttacta ttttacaaaa aagagcaact tttcgaagaa atatttaaat acatattaaa
    74341 atttttttat attttcatgg gacttcatta aaaaaatatt agttttctta ctaaattgat
    74401 acattattgt attaatgtaa tggaaatgcg attaatttaa ataaataaag aagtcatttt
    74461 ttgtaatata gcaacttcat tttttttatt aataaacaaa atagataaaa tatattttga
    74521 ggaggggtga gtgtgaatac atatgacatt ataaaaatgg gattagatgc aactaatcta
    74581 agaagtcaga caatagcaaa taatatagca aatataaata ctgaaggata taaaagacat
    74641 tatataactt ttgaagaaac actaaatgat gctatgccta aaatagaaga aaaaacagac
    74701 aattctaaag gtttaagagt agatggtaat aatgtagaca tagaagaaga aaaagtaaat
    74761 caagcaatgg caacattaca atataatgct ttgataagtt ttgcaaatgg aaaaatagca
    74821 atgaccaaat caataataag tgggaggtaa ttagaagatg agtgtgttca gtggaatgag
    74881 aatatctgct agtggattaa cagcagaaag tttgaaaatg gatatcatat catccaatgt
    74941 agctaatata aatgctacaa gaggtccaaa tggagaagca tataggagaa aagttgtttc
    75001 atttgaagaa aactatgata ataaattagg tatgctagga gtaaaagtta catctgttga
    75061 agatgataaa tcacctctta aagaagtata tgacccatct catccagatg caaagccaaa
    75121 tggatatgta gaatatccaa atgtaaatat attggtagaa atgacagatt taataacagc
    75181 ttcacgagca tatgattcta acgtagatac attgaatgct cagaagtcta tgatatcaaa
    75241 agctttggaa ataggaaagt agggataaat tatgccaatt acacaaatta acaatttaat
    75301 gcaaggtgca aagttagata atttgattgg agaagcaaag ccattaactc ttaataataa
    75361 agaagaaaaa aagaattttg aagatgtaat aatagatact atagataaag ttaattttca
    75421 acaagtaaca gcagatgata tgaaagaaaa atttataaaa ggcgaagatg tttctatgca
    75481 tgaagttatg ttaataggtc aagaagcaca actatctatg caatatttaa tagaagttag
    75541 aaataagatt catgatgcat atcaagaaat gaataaggtg caaatttagc cttttgaaca
    75601 ggagtaataa tcaatgataa ccagttttaa aaataagatt aaggagcaag ttgctaaatc
    75661 taggacaaag ataagttctt taaaaaaggg aactaaaata gcattaggta taggggttat
    75721 tgctatatgt ttagcgctag tatttacagc aatatctgcg agcaaaaata agtatgcagt
    75781 cttattttca gaactagatg ctcaagatgc tgcagatata tcagcagagc tagagtctaa
    75841 aaagatagat actaaggtaa aaggaagtac gatttatgta cctagaacag aagttgataa
    75901 gttaaggctg gagttagcgc caagtcttac aggtggttct aaaggatttg cactaatgga
    75961 tgatagttca tcaatagggc ttactgatga agaatttcag attaagaaac aaagaatgat
    76021 acaaggtgaa atagaaaaaa caataaagag ttttccacaa gtggaagaca ctagagtaca
    76081 tataacattt ggagagtcat cagtatttga gaaggaggct gttccaggga gtgcagcagt
    76141 ttatttgatg ctaaaaccag ggacgacttt agaaaaaaac caaataaagt ctgttatggc
    76201 acttatatca ggaagcgtta caaatatacc agagaaaaat gttcaggtta ttgataacaa
    76261 aatgaattta ttatctgaag gtattttgga ggatgaaaat gttgatgaaa ataatcaacc
    76321 aataaatagt ggcattagtg ttgataaaaa taaggcatct gaacaagcat tgaataaaca
    76381 actagaaaag tctattttag aaatgctaga accgatattt ggtaagggaa aggtgaaagc
    76441 tacagtaaat gctgatttaa gttttgatac agctgaaaaa actgagataa aaattgaccc
    76501 tgataaagtt gcaataaagg agacaaggtc gaaaaattca tctaaatctg ctgcaaataa
    76561 tgttcaaggt gtagatgcta acatgaataa ccaaggaaat aacaatggta ctaatacaga
    76621 agatagttta gatgagagtt ttgagtatga aacaggtaag attgaaactc acactatagt
    76681 tgcgcctgga gaacttaata gattgacagc ttctgttgca atagatggaa aaatagctaa
    76741 aggtgttcaa gctgatgtag aggatattgt taataatgct ataggtatgg atggagcgag
    76801 gggagatact cttagcgttg tttcaatggt atttgaccca gaaggtaaga aagaggctaa
    76861 acaagagctg gaagagatta aaaaagaagg atttaaaaag aacataataa aagcagttat
    76921 tggagtagta gcagtaatag cagttggagc tattggatac ttaatatata agaaaagaag
    76981 tgaacgagaa gatatggatt atgaagatga agattatatt tctaaatctg attctgttga
    77041 taggaaggat aatcctctat taggagatga tccagaactg acattagagg aagctgttaa
    77101 aatgtatgca gaagaaaagc cagaccaagt aacagagata ataaagactt ggttaaatga
    77161 gtaaggggga tagaaagtgt ccacggaaat tacaaatgtt aatgcgtttg acttaagtga
    77221 tataaatgaa agtgataaga atgagaaggt agaaggtgag ggtttaaaaa aagctgctgt
    77281 attattaatg acattaggcc caaatgtgtc tagtgatata ataaaaagct tgcctgataa
    77341 acaagttcaa aaaataggtt tggaaattgc aaatatttct tcaatagctt caaaagaaag
    77401 aagagaaatc ttaaaagagt ttgtagaaat aaatagggca aaagattatg ttatagaagg
    77461 tgggcttgaa tatgcaagag agttattaag taatgcttta ggaaatgtta aagcaaacaa
    77521 attacttgaa ggtatatcaa taaatacaag tacaaagcct tttaaacata ttataaaact
    77581 agatgtaaag aagatattag aaatacttag gaatgaaagt gcacaaacta tagccgtttt
    77641 acttgcacat atggaaccag aaaatggagc agaagtttta tcatacttag attttgattt
    77701 acaaaatgaa gtagctatga gaataagctc aatgggttca atatctccag aagtaataaa
    77761 ggtaattgaa agttcattag aagataaatt acattcaata agtggtgatg attttaatga
    77821 ttatggaggg gtgtctacct tagttcaaat attgattaat tctgatagaa aaacagaaaa
    77881 gaatattttg ggaactattg aagaacaaaa cccggattta gcagctcaaa ttaaatctca
    77941 tatatttgtc tttgaagata ttgtcaagtt agatgatata agcatacaaa aagtgttaaa
    78001 agaagtgact atgaaagatt tagtatatgc cttaaaaggt gtagatgatg agatttcaga
    78061 tgctatatat agaaatcaat cttctagagc agcagatgca cttaaagaag aaatggaaat
    78121 ggttggtgtt ataaaggtta cacaagttga ggcttctcaa caaaagatag ctaatatcgt
    78181 aagaaaactt gaaagagaag gtgccataac tattgtaagg aattttggtg gtgactttgt
    78241 tgaataataa gattattaaa agtaaaaaag cattatataa aggagtgcta gatttaacca
    78301 taatagataa agttagagtg ggagaatcaa atgtaaataa agaaaatgat tgtagattta
    78361 gggatgaggt aataaaagaa gctatagaat ctgctgagat aaaaaagaat gagatattag
    78421 aagaagcaaa aataaatgca caaaatatag aaaagcaagc atatgaaaaa gggtatagtc
    78481 aaggtcaaaa aaatggatat gaggatggat ataaagagtc atatgatgaa tatacccaaa
    78541 aagctaaaga tgaagcagat tttataaaaa atcaggcaaa tttaatctta ttacaagcta
    78601 atgagaagat gactgagtac ataaaagaaa aaaataaaga gattgtaaga cttgctatta
    78661 atatggccag ttctgtttta aaaaagcatt tcgaagatga agaatctatg agtgatctgt
    78721 taaagcaaat tattcaagat tatgaaggaa gtagttcatt tatagtaaga tgtaattctt
    78781 tctataaaga taatatagag aaagagtttg aattattcaa agaggaaaca tcactaaaat
    78841 caagtgtatt tgttattgca gatgatagta tagataaagg caatgctatt atccaaaagg
    78901 aaaatggaag aataatagtt ggtattgatt gtgctatgga aaaactaaaa gaagaattgc
    78961 ttggtgaata aagtatgtat aaaactgata tatctataga ttttgacaaa ataaataaga
    79021 aaatagaaaa tttagaactc actatatcag aaggtagagt aaagaagata ataggactta
    79081 ctgtagaagt tgaaggaata aaagcttttg ttggggagtt atgcgttata tacaaccaag
    79141 ttaataaacc agtgaattgt gaagtagtag gttttaaaga taaagaagtc atattaatgg
    79201 cgttgggaga attaacattg atagcacctg gttgtaaagt tatttctaag gggatacctt
    79261 taagtgttat gtgtagtgat aatttactag gtaaagtact tgatggtctt ggaaatccta
    79321 tagacaactc agatgctgtt ttaggagata gatacaacct gaacaatgaa cctcctgatc
    79381 caatgaagag aaaaaagata cgaaatataa tggaaacagg tgtaagagca atagatgcat
    79441 ttactacttg tggtgaagga cagagaatcg gcatatttgc aggaagtgga gtaggtaaga
    79501 gtacgactct aggtatgatt gctaggaatg caaaagcaga tgtaaatgta attgctctta
    79561 ttggagaaag aggaagagaa gtactagatt ttattgataa agatttaggt gaagagggaa
    79621 tgaaaaaatc tgttgttgtg tgtgcaacat cagataaagc ccctctagtt aggttaaaag
    79681 gtgctcttac tgctactgca atagcagaat attttagaga ccaaggcaaa aaagtaatac
    79741 ttatgatgga ttcagtaact agatttgcta tggcacaaag agaagttggt gtagcaatag
    79801 gagagccacc agctcaaaaa ggatatacac catctgtatt tgcaatgttg ccaaaactta
    79861 tggagagaac agggacatca gataaaggtt ctataactgc attttataca gtattagttg
    79921 atggagatga ctttaatgag ccaatagcag atacaacaag agggatactt gatggtcata
    79981 tagttttatc tagagacttg gcaaataaga atcactatcc ttctatagat gtattaaaca
    80041 gtttaagtag gcttatgaat gaaattgctt caaaagaaga cataaaaata gcgtcttttg
    80101 caagagacat gcttgctgag tatagagaag cagaagattt gataaatata ggtgcatatg
    80161 cttcaggtac aaataaaaaa atagatgaag caatctatta tcatgagcat attattaatt
    80221 ttttaaaaca agggataaat gaaaagagtt cttttaatga aactataagt agtttgagaa
    80281 gagtttttga ataaacaatt aaaaaaatat ttgaataggt tgtgatggaa ttggataaaa
    80341 actttaagtt tagattacag aaagttttag acttaaaagt gaaagatgaa gaagagataa
    80401 aaatggaatt tgctaagatt caacaaaaaa aaatagatat agagactaat ttagaaaact
    80461 tagaaagtaa ttatagcaaa tattctataa gtaaaaataa cgatagtatt caaaatcaaa
    80521 aaataactat taactattta ctagctttaa acaattctat aatggattta tcagaagagt
    80581 tggataagtc aacaaatgaa cttgaaaaag ctagaaagca gcttataagc aaacagatag
    80641 agagaaaatc attagaaaaa ttaaaagaaa aaaagtatgg acagtattat aaagaagaaa
    80701 atttaaaaga acaaaacact aatgatgagt ttgcaagtat gagttattta aggaatagac
    80761 aagttctata agaatagtag gaagtgagga tattattgta tgaagataca agcagattct
    80821 tataatatta ttaaagatat tggggataga aaaagttcat ctaagaacaa aaatataaaa
    80881 aataataaat ttgaagataa tctatataag gcaacagacc ataaaaaagt taaagataga
    80941 agggaagtaa gtaagcaaaa tattagctca gataaaccgg aaaatagtga taatgagtgt
    81001 catttagatg aagataaaag taatcactta gaagatgaaa atacatatga aaaagattgt
    81061 agtaagaata atgaagcttt gcagcaatta ctgaatcttt taaaggataa ttataaaaaa
    81121 gataaagata taaacactat attgaataat atagaaaaac taagtatatc agatgaatta
    81181 aaacaagaac ttaagcttaa taaaaatata ttaaataaga ttgcaaatca aaattcagag
    81241 ctaaataaag ctaatataaa taactctaat gatatagaaa atttagacat agttaaatta
    81301 agagaacttt tggaagataa tgctaataaa gatattgaag taattactaa aactacagaa
    81361 aatgatacca aaaatataga tttgtatagt tttgatagca atagaatgga taatcttaac
    81421 tcaaataaac agaaagatga tagctctgat attttggaaa aactagcagg ggtaaatgga
    81481 aataagagtg ggaattttgg acaagtaata aataaaaatg ttgatatgaa taaaattaaa
    81541 aatgataatg tcaatttaaa acagatagaa tcaaatgtaa tggatgactc tataaaagct
    81601 attaagcata tgaaaacaaa tgatatacaa gaattgacaa ttaaattaag accaaaagaa
    81661 ttaggagata tgaatataca attgttaaaa gatggtgaaa gtatgagagc tgttgtgact
    81721 gttttcaata aagatgtctt tgactctata aataaaaaca tagcagattt aaagcaacat
    81781 cttgaactta ctaatgtaaa tataaaagat gtatcagtgc aaatgcacag cgataataca
    81841 aatacatctg atacctttga taaagcattt gaacaacaga atagacaaaa taaccaagaa
    81901 aacatgagta agaagaatac aaatgataag cataataatg tagtcataga agatgacatt
    81961 aaagaaaata ctattgatga tgatagagta gatttactag cttagtaagg gggaagtatt
    82021 gcatgtacgg aatagcaacg gctttggcag gaactcaggg aaactatagg tcaaatagct
    82081 taagccaact tgaaagaaat attaatgata ttgccaataa acaagttaga agcaaaggaa
    82141 atcagacagt aacagacaat gggactccaa ttataggaca aggtgatgat gctgataaag
    82201 acttgtttat gaagatactt gtggcacaga tgggtaatca agacccaatg aatccgcaag
    82261 acccaacaga atatgtgtca caattagcac agtttgcaac tttagaaaag atgtcagcta
    82321 tgaatgagaa gctagatgta cttttagcct taagtaattc cactctaata aactctgctt
    82381 taagtatggc aacatcatta attggtaaag aagtagaagt atctggggaa gagaaagaag
    82441 atgaaaacat tgtaggagta gtaaagtcca catatataaa agatggggaa gtacacttag
    82501 aattagaagt agatggaagt gacaaaactg taggtgttaa atatgaaaaa ttacttaaaa
    82561 taggagaggt agatgaaaat tcaggagaag aaaatgattc ttcagaacac gaatctccag
    82621 aagaagcata atattaaatg agaaaagagg taaattcatg ataaaagcaa tgtattcagg
    82681 tgtaagtgga atgaaagcaa atcaaacaaa attagatgta ataggtaaca atgtagccaa
    82741 cgctggaact acttctttta agaaaagttc agctagaata acagattcat tttatcaaac
    82801 tgtactatat gcaagtgctc caacagctgc attaggagga acaaacttag gacaagtagg
    82861 tgtaggtagt aagatatcaa gtataaataa agatatggta caaggaaatg tacaaccaac
    82921 taatagacca tctgatttaa tgatagatgg agatggatat cttccagtag taagacaagg
    82981 aacagttatg tatacgagag atggttcttt taatttagat acaggattta aagcagctga
    83041 tggtgctttg aagaatatta aaggtggaag acttgtaaat ggtgatggat atatgttaca
    83101 aggtatgatt tatgatgggg aatataaagc tgatactgga gaatttgtta aaaagggtga
    83161 tgctaaagga aaagagccta ttgtaatacc acttcaaagt ataagtccta aggatggaac
    83221 agttcaaaat gtactagagt ataatatatc aaaggatgga acagtagaat ttttattgag
    83281 tgatggtcaa agaactcaat ttgtctatga tatacctgat ggtgctaagg taggagatac
    83341 acctgctgga atagataaat taaaaggtac aatacaaaaa gtgcaaacat atgcattcca
    83401 aaatccagca ggactagatg cagaaggagg aaacttgttt aaaccatcag caaactcagg
    83461 agacccacaa atagcaggag ctacaggcac aataatacaa ggggcaatag aagcttccaa
    83521 tgtagatata gcagaagaat ttacagaaat gataatagca agtaggtctt tccaagcaaa
    83581 cagtaaaata atatcgacat cagacgagat acttcaagaa ataataaatc ttaagagata
    83641 gtaggtacat attatgataa gagtaacgga tttaaacgga agaaaataca tattaaattc
    83701 agaccttata gtgaggattg attctgtacc agaaagtagg attctcctta caacaggaga
    83761 aaaaaacctt gtaaaagagt cggtagatga gatagtagat aaagtaataa agtataaaag
    83821 aaaaataaat gtaggttata ttaggagcga aaaataatga aaaaaacaga ttcactgaca
    83881 tttattggac taatagtatc tacagtatta gttttagttg gtgccgcaaa aggaagtagt
    83941 tcagggttaa agaatttttt tgatgtttca tcaatattaa tcacagtgct tggttcattt
    84001 ggagctctaa tgattacatt tactatagat gatataaaac ttataaaaaa tgcattacaa
    84061 tactcattta agacaatgag tgtatcaaag ttagatttac tagaacaatt taaaacactt
    84121 tctaaaaaag ctagaaaaga aggtctttta tcaatagaga gtgatgtaat gggaatagaa
    84181 gatccattta tgaagaaagg gttagagctg tgtattgatg gattggaaat caatgagata
    84241 aggtccatct tagaactaga gatagattct gttgaagata caaataacag atactctaaa
    84301 ctatttaaaa cttggggaac ctttgcacct gcttttggga tgttgggaac actaataggt
    84361 ttaatacaaa tgttagctga ccttacatct ccagatttaa tagcatctgg catgggaaag
    84421 gcattaatta caacgtttta tggttcttta cttgccaata tcgctttgaa cccaattgca
    84481 tataatatag atgagaagac tgaaaaagaa atttatgtaa aggaaatgat gttggaaggt
    84541 ataataagca tacaatctgg ggagagcagt atagtagttg aggaacgttt agccacatac
    84601 ctttcaaaca atgagaagtt agaaattatg aaatccaata aaaatacaga aagagcaatg
    84661 agcaatggcg cgtaaaaaaa ataagaaaaa ggatgagata aatccagatg catggctggc
    84721 tacttatgca gatactataa cactgattct tacatttttc gtattattgt atgcaacatc
    84781 agttgtagat atggaaaaat ttaaaaacat agcagatgcg ttaaaaggtc agttttctgg
    84841 gacaagtata tttagtacgg gttcaagtac aagtgagaaa tctccaatag acagtgtttt
    84901 agtggataaa aatgataaat caaatttaga acaggattta aaagataaag ttaataattc
    84961 taacttacaa aatagtgtaa cagtcaaaga tgatagtaga gggattttac tagagttaga
    85021 tgattcaatt ttatttgact ctgggatttc tgagttaaaa gtagatagta aagctactct
    85081 taataaagta tatgacatga taaagatgat gaaaaataag atagttatag aaggccatac
    85141 tgataatgta cctgtaaaat caagtacaca tgaatccaat tgggatttat cttctagtag
    85201 agcagtaagt gttgtaagat actttgtaga agaaaagggc atggacccta gactattttc
    85261 ggcaacagga tgtggagagt atcaaccttt ggtttcaaat gaaacagcaa agggaagggc
    85321 tgagaataga agagttaata tacttataac tattgactag gaggaagagg tttgttcaaa
    85381 aataaaaaaa ttattataat tattttgata ctgattattt tctcagcggg agcaggtttt
    85441 tttatattag gagaaggtgg aaataaacaa gttgacaaga ttgcagattt gtttattcca
    85501 acaggaaaag gtaaagatga agtaaagacc gaaaatcttg acttagaaga gatggtatta
    85561 aagctagctg atgaaggtgt aagatattta aaagtatcaa taactgtatc ttatgattct
    85621 tcatataaag atatagaaaa aaatacgcct ttaattaggg ataatattat aaattgtttt
    85681 atggcaaaaa gggcagatga ttttactgct gataatttaa agaacataaa agaagaaata
    85741 aaaaatacat taaatataca actaggtgaa aatgtaattc aaaatatata tttcacaaat
    85801 atagtagtgc aataaaagga tggtaagaca tgatacttta tttactaaaa atattaatat
    85861 gtatcccaat aattttaata ttgatagtct tatctttaaa aattagccaa ggaactttat
    85921 taaaaaaata taatgataaa tatgtaaaaa tactagatat tgtaaatata agtaaaaaca
    85981 atagcataat aattttaaaa ataggtgaag aaggatgcat tatggcatct tcttcttcta
    86041 gcatgagtaa aataaaagat ttgaccaaag aagaaatatt aaaaatagaa aacgacatta
    86101 aagaaagaaa ttttaaaatt caagatttta aaatggaaag aattaaaaag aaatatgatt
    86161 tcagtagata tattggaaaa tttacaaaaa aggaagataa gtaaatggaa ctattatcaa
    86221 aattaccttt ggctgatgta ccatatacaa gttcaatgca attgttttta tttctaactg
    86281 cattaatgtt tttaccattt gtaatgttca tgatgacaag ctttgtcaga atagttataa
    86341 gtttatcatt tttgaaatca gcattaggag cacagcaagc aattccaagt caaattttgg
    86401 taggacttgc aatagtattg acaatattta taatgagacc agtattaaat gagataaacg
    86461 aaaaggcatt acaaccatat atgaaagaag aagttactat ggaagaagct atgaaggaag
    86521 cagaaggacc tattaaagag tttttattaa cacaaaccag acagacagat ttagatttat
    86581 ttgtagaaca ggctggttta aaagaaaaga aattaactcg tgaaaatata ccactatctg
    86641 ttgtagttcc agcatttgct ataagcgaac taaaaactgc ttttcaaata ggttttttaa
    86701 tatatatacc atttttgata atagaccttg ttgtggcaag tgttttgatg tctatgggta
    86761 tgtttatgtt gcctccagtc atgatatcat taccatttaa gttattatta tttgtaatgg
    86821 tggatggatg gaacttgata gtaaaaacat tgatattggg atttggatag gagaaaaata
    86881 gtatgagtga atttatgata atgagtgttc ttaaaaatgg catgtttaca ggagctatga
    86941 ttgcagctcc agtactcatt gtttctcttg tagttgggct tttaataagt gtgtttcaag
    87001 ctacaactca aatccaggag caaactttga cttttgtacc aaaactaata gctattcttt
    87061 tagtagtagc tattggtgga agctggatgt tacatactct tattagtttt acttctgaga
    87121 tattcaatat gatatctctt ataactaaat aagtaggata catatgattt ttgtatttat
    87181 tagaatagta gcattctttg gaacactaag aatactattt ccagctggta cacctgcttt
    87241 atttaagtca ctctttgcaa tcattatatc aatattgatt tcaagtacta tgcaaattga
    87301 atatgcaaca aatatagaca acattgtatt gtttacctta tatggtgtaa atgagaccat
    87361 aactgggatt atgcttggat atataaccaa cctatgtttt tatagtatca gaatggcggg
    87421 ttctatgatg gaccaacaga tgggattatc aatgattaat atgtttgacc caaattcaat
    87481 gactcagaca actttaattg ataatcttat gaactggaca gcacttatga tattttttag
    87541 catggatggt catcatgttt taattagagg tataaggtat agttttgagt taattccaat
    87601 aggaaaacca tttgtagata ataacataga ttatataata aacatatttg tgcagtgctt
    87661 tttaactgga ttcaaaatag caatacctat tgtactttgt ctgcttatgg cagattttat
    87721 tttagggctt atatcaagaa gtgtacctca attaaatgta atgatagttg gtatgccatt
    87781 aaaaatattg gttggtattg cattatttat catatcaata cctttaattg tcaatcaaat
    87841 aagtcattta ttaagtcaaa taccaaagat gtatgaggga acttttgcac tagctcctat
    87901 gttttttatg ggttcagcag ataaaacaga agaagctact ccaaagaaaa agggagaaca
    87961 aagaaagaaa ggtaatatag caaagagtag agaattaccc gttgcaatga ctctacttgc
    88021 attcacctta ttagtaccta cattattttc atatgtagta gatacactta aatcttcgct
    88081 taattatttt ttgagtctag atttttatat gaacataaat tattcaaacc tagagaaatt
    88141 agttatagca ggattaatgg atttttttaa gatattttta ccaatagcta ttcccttttt
    88201 agttttaggc ataatagcaa acctatttca ggtgggaata ctgtttactg gtgaaacttt
    88261 aaaaccaaat ttatcaaaat taaatccaat tagtggattc aaaaacatgt tttctatgag
    88321 aagtttgtca accttaataa aggatacagc gattatatct attttggctt acataggata
    88381 tacattcttc caagataatt atttagatat attaaagcta ggtaacatat acctaccaac
    88441 tttaatgtac acagttaaag acttagtata ttcaatattg agtaagattt gtgtagctat
    88501 gatagctata gcagttgcag attatgttta tcaaagatac agtcataaaa agcaactgag
    88561 aatgacaaaa caagaagtta aagatgaata taaaaactca gaaggagacc cagaagtaaa
    88621 agctaagata aaacaaaaac aaagacaaat ttcgtctcaa aggacaatgc aagcagtacc
    88681 aagtgctact gtaatagtaa ccaatccaac ccacttatct atagcagtga gatatgaaaa
    88741 agggaaagac caagctccag tagtggtggc aaaaggtgca gattatctag cttttaaaat
    88801 aagggaaatt gcaaagggaa ataacatccc tataatagaa aacaaaccta ttgctaggtt
    88861 gttatataag caagtagaaa tagaccaaga aattccagag gacatgtatc aagcttttgc
    88921 agagatatta gtggcagtat ataaaatcaa aaatagatac aaagtcccca aaaggtagga
    88981 taagtaatga ataagtttaa tttaaaggaa aatatggatg taatagtggc atttggtgtt
    89041 gtagggattg ttcttatgat gatagtgcca ttacctacat ttatattaga tattttactg
    89101 gcaattaaca taagtttatc tgtgctaatt ttactaatga cattatttac aacaaatgta
    89161 cttgatttat ctatatttcc aacagtgtta cttgtgacaa cactatttag attgggatta
    89221 aatctttcat caactagatt gattttaaca cagggatatg caggtgaagt tatagaggca
    89281 tttggaagtt ttgttgtagg tggaaattac gtagtaggaa taattatatt cttaattata
    89341 ttaattgttc aatttgttgt tataaccaat ggttctggaa gagtatctga agtaacagct
    89401 agatttacgt tagatgccat gccaggtaag cagatgagta tagatgcaga tttaaatgca
    89461 ggagttatag atgacaaaac tgctagaaaa agaagaaaag agcttcaaca agaagcagat
    89521 ttttatggtt ctatggatgg agcaaataag tttgtaaagg gagatgccat agcaggtctt
    89581 atagtaacag caataaacat aataggtgga attgtaatag gagctgtaat gctgaatatg
    89641 actcttatgg gtgcagcaca gacatatgta agacttacta taggggatgg tcttgtaagt
    89701 cagatacctg ctctattaat atctacatca gcaggtataa tcgtaacaag agcttctact
    89761 gatgaaaact ttggtgactt agtaggtaaa cagttaacgg caataccaaa agcagtaatg
    89821 atgactggtt gtgttctaat cgtacttggt atgatgcctg gattacctaa accagcattt
    89881 ttttcactag gtataggagc tatagcagca ggttactttt taggaagaga aaagaaagat
    89941 actttagaag acttggagtt tgaaaaacct gatatggtaa acccagataa aaatgaagta
    90001 gaagatgtaa caaatttaat aaatgtagaa tcaatagaag tagaaattgg atatggttta
    90061 atatccttag ctgatgaatc agcaggagga gatttacttc agagaatagc atcaataaga
    90121 agacaatgtg caatagatat gggtatagtc gtacaaccca taagaataag agataactta
    90181 cagttaaatc caaaccaata caatataaaa ataaaaggaa atgtagttgg tgggtatgag
    90241 ataatgccta atatggtttt atgtatggac cctatgaatc aaggatttag tatatttgga
    90301 ataaagacaa ttgaacctac ttttggaata gaggcacttt ggatagaaag tgacaaggta
    90361 gaagatgcag agttaaaggg ttatacagtt gtagattcat ccacaatact tataactcac
    90421 ttactagata taataaaatc aaatgcacac gaattactgg gaagacaaga agttaagact
    90481 attatagatg cagcaagaga aaattatagt gctgtagtag atgaattgat accagatttg
    90541 atgacacttg gtgaaattca aaaagtactt aaaaatctgt taagagaaaa agtaaatata
    90601 aaggatagag ttacaatact tgaaacgctt gcagaccagt ctagaaatac aaaagatata
    90661 gagcttctta ctgaatatgt aagaatagcc ttggctagaa gtatttgtaa taatttagtt
    90721 gatgatgata agacaattgt agtggctaca ttgtctccag aaactgaaga gttggtatct
    90781 aataatttac agaggtctgt aaatggaact tatccagcag ttgacccaga aaatacaaat
    90841 aaaatatttg aaagtataca agaagtaatg agcaatgtat atttcaatca taatatacca
    90901 gtaatagtag tatcaccaaa gataagagct ccatttagaa aattagttga aattgtatat
    90961 cctaatttga ctgtattatc attaaatgaa atacctaacg atattaaaat caaagcagaa
    91021 ggtgtggtga gcatatatga tgacgaaaaa gtatacagct aacacaattc aggatgctat
    91081 gaatctagcc aaaatggaat tgggtgacaa tattacatta atagataaaa aagaggtaag
    91141 aaagtctgga atacaaggta tcttttcaaa aaaagatatt gaactaacta ttggatggga
    91201 aaagagagaa aatgtagaac aaaaagattt aaaacgagag atagaacaat taaagtcaat
    91261 tattaacaat atggggtttg ataataagaa tgataatgat atagataaaa tatgtaaaaa
    91321 tctactaagt ttagaattga atgaagaaat tgtagaatct ataagaattg atttgcaaga
    91381 aatgaagttc aatggaatcg atacaagtaa aaatttagta gaaattttaa agaaaaagat
    91441 taaaatagaa aatcaagtaa taaatggtaa aattgctcta gtcggaccac caggagtagg
    91501 taaaacgact acaatagcaa agttagccgc aaaattagtt tttgaagaaa ataaaaaagt
    91561 aggagtaata actatagata catacaggat tggtgctgta gaacagttga agatatatac
    91621 tgatataatg aatattccct ttaaaggggt aataagtcct gatgaaatgg aattggcact
    91681 tgacgagatg aaagattgtg atgttgtatt aatagataca acaggtagag gctacaaaaa
    91741 ctctatgcaa atactagaaa tcaaaaatct tatagataaa gctgaaactg ataatataca
    91801 tttagttttg aattgtacaa caagagaaag tgatacaaaa gcaattatag attcatatag
    91861 aaatgtgaat tttaaaagct taataattac aaagctagat gaaacaataa catatggctc
    91921 aatatttaac ataatgaatt atgcgcaaaa accaatatca tatattacaa caggacaaaa
    91981 tgttcctgat gatattataa aacctaatga agataagatt ataaggttac tattaggagt
    92041 tgaaagtata tgatagacca agctcaaatt ttgagaaaaa tagcaatgga aaaaagagga
    92101 cttgatgagt ttatagtaga gaatgagaat gtacctaaga taattacaat agcttctggt
    92161 aaaggcggtg ttggaaagag caatctcgct acaaatttgt ctatatgctt gaccaaactt
    92221 aataaaaaag ttcttatatt agatgcagac ataggaatgt ctaatataga tataataatg
    92281 ggggtaaatg taaaagggac tataattgat gtaattaatg gcgaaaaaaa tatagaagat
    92341 ataatttcac agactaagta tggtgtaaat ataatatctg gaggttctgc ccttaatcat
    92401 atagaagact ttacagaagc tcaaagaaat aagtttatac atagcataga acaaattcac
    92461 gatgtggatt ttataataat tgatacagga gctggtatga gcaaaagcct attgtcattt
    92521 atatactgta gtactgaatt tttcttaata acaactccag aaccgacatc attgactgac
    92581 gcatatagtt tattaaaagc tataagtaat tttggcataa agagaagtgc aaatataata
    92641 atcaataggg taattgattt agaagaagca aaatctacat acaaaagaat aaaaatggtt
    92701 gtggacaaat ttctaaacct taatctagaa ttgtatggat atataataga tgacaaaaaa
    92761 gtaagtttat gtgtaaaaaa acagatacca ttcattttag aatatcctac aagtattgca
    92821 tcaaaatgta ttatagccat agcaaagaga atggtaagtc agtcaagaga agatattgtt
    92881 gataataaaa gttttctaag aaagatgttt agtatattta aaagctaagg aggcgtagtt
    92941 aatgaataga gaagaattaa taaaagagaa tatgcctctt gtaaagagta tagcaagaaa
    93001 attttttata ccagggaaag gttttgaata tcaagactta gtaaatagtg gagtcattgg
    93061 attgattgat gcaataaata aatttgatgc tgaaaaaggg gcaaagtttt ctagttactc
    93121 ttatataaaa ataaaatctg ctatattaga tgaaattaga aatcaaagtc caatttctaa
    93181 acataatcta actaaagtaa ataagtataa tagagtggta gaaaagttgc aatctaaatt
    93241 attaagagag ccaacttcat atgaaattgc aaaagaatta aaggtttcag aaaaagaact
    93301 tcatgatatc gaaagtaata tagatatgtt aaatattgta tcattaaact atgtaatctt
    93361 tgaagataca aatgaaactg tacaagatgt aataagtgat agagaagagg aagctccaga
    93421 aaatataata gaagaagaag aaaagttaga gattctatcc aaagcaatta gtaatttaaa
    93481 tgaaagagaa aaattaatac tttcactgta ctattatgaa gatttaaatc taaaggagat
    93541 agggaaagtg ctaggtgttt cagaatcaag agtttcacaa ctccacagaa aatcaataag
    93601 aaacttaaga aacaagataa aagaacttaa atattctata tagatggtga ttgataagat
    93661 gatacaaatt atattaatag tagtgtctat tttaataata gtaactatag ttataaattt
    93721 acataaggaa tcaaaaaata aagataacag atactttgat aaaatatttg agcaagaata
    93781 tgaagcaaat gatagattaa taattgcaga aaaaagaaga ttctttttag acaaagtact
    93841 tgcagaaaaa agaattaata gtcatataaa agtttatgaa aattataacc taataaaggc
    93901 taatgaagaa agaaaggaaa acatatttat agaatcaaaa aaggaagtaa gacaagaaaa
    93961 tgagttatct cttaaagtga aacatcttat aagttcaggt tatgatgatg tggaaatatg
    94021 taagatgcta gatattggaa agggggaact gttattaata aggagttgtt acaaaatata
    94081 aggatattat tatgtgataa aaaagtattc ttaggaatag gtattggtat attaatatca
    94141 actttatgta taatgctttt tagtaataat gatatgagta aggcagagat agaaaaaaag
    94201 gccagagcgt taggcatgaa atatacaagt gagatgaaag ttttagaata gatgatattg
    94261 tttagacatt tacaaaaaag gaggtcataa tgtgataaga ggattatata cagcagtttc
    94321 tgctatgata actaatcaac aaaagcaaaa tgttgttgtc aataacctag ctaatatgga
    94381 tacaaatgga tataaaagta aacaactttt gactaaaagt tttgatgaat taaagttgga
    94441 gggttacaat aactacgcaa atggaactaa acaaaagcag attataggcg atataagtcc
    94501 aggtatttct atggatgaaa ctatcacaaa ttttaatcaa ggacctataa aaactactga
    94561 taataaaatg gatgtagcta ttcaaggtaa gggatttttt ctagttagtg atgcagctgg
    94621 aaatcaattt tacactagaa atgggaactt cagaacagac aatcaaggtg accttataac
    94681 aagtgaaggg tattatgtac ttgggacgaa tactgctact ggtgctgtag gtcatataaa
    94741 tgtaggaaat caaaaatttg aagtggcaaa agataataca atatcactag acggaaatgc
    94801 tatgtataaa tttaatattg tagattttaa taactacaat aacttaaaaa aagaaggaga
    94861 taacttatat tctggaggag gagctatgaa agtaaataat gcacttacaa tacaaagtgc
    94921 gatagagtcc tctaatgtag atatggtatc tgaaattaat aatatgatga caatatcaag
    94981 agaatatgag gcaaatcaaa agataattca ggctatggat tctaaattag caaaaatagc
    95041 aagtgagatt ggttcagtaa gataggtaat aggaggtgaa tttttatgta cacaatgttt
    95101 tatactagta aaacagcttt atcagcaaat caaagtaaac tagatataat atctaacaat
    95161 atagcaaatt ctgattcaac aggatataaa aaaataaata tggaatattc tgatttagtg
    95221 gatgaagtac taaatagacc atcatatcct acaaatggca atgatatatc gactggaaca
    95281 ggagctaagg caacagctcc catgagaaat tatgaacaag gtgcattggc tcctacagat
    95341 agtaagagta atttggcaat agatggagaa ggattcttta gagtgataag aaaagatggt
    95401 acatatgcat atacaagaaa tggtggattt aatgtagatg ctttaggtaa gattgtagat
    95461 gataatggaa atatattaga tgtccaattt gatgcaggat ataactataa taatacaaat
    95521 atagatagta caaacctgac agtttcaaga aatggagagc tattcgtaga taataaaaaa
    95581 ataggaaaaa tcaacttata tcaacctata ggaactcaaa attttatatc tgaaggagat
    95641 agtttattcg tcgcaactga tgcagcacag attaaacaag ttgagaaagt cgatatagtt
    95701 caaggctata gagagaggtc aaatgtttct ttacaagaag aatttgttga cttaatagcc
    95761 actcaaagag catttcaaat gaactcaaag ggaataaaga cagcagatga aatgtggcaa
    95821 atagcgaata atttaagagc taaataatta tgtaaggtga ggaatattca tgaatgatat
    95881 gaaagagtac gattttggca aacctcagag ttattcaaga gaaaatttaa cttgtttaaa
    95941 ttttttatta gctgaatttt gtaaaaaata taaaaactat ataatttatg aacttaagtg
    96001 taattctagt atggttgttg atagtataga ccaagtaaat tatcagactt ttttagatag
    96061 agtaacttct tcatgcgtag tagtacaaaa tgcaatggaa cctgttatga aaaacttttc
    96121 ttttagaata gatagaagtg tagctgatat gtggattgat ataacttctg gaggaactgg
    96181 agttgtaaag gataatgata gagaacttac agaacttgat aaaaaagtgc ttttacacct
    96241 tatggatgat ttagtaagaa atatgcactt atttgagggt tttgaaaata tacaagtatt
    96301 ggatacacat acacatatta atttgccaca attatgttct ccaactgcac cagtatgcgt
    96361 tgtagattta aaagtgctaa atgataatga gtatattgga agtgtttctc tttgctttcc
    96421 atacaatggt ttagaggctc tgttagaaag tatatctgtt atagaatttt ttgataatga
    96481 tgtaggagat gattcagagg aatttaccca aaaaatctat aatagtgtat ctaatataga
    96541 attatcagtt attgcagaga taggaaaagt atcaattaat gttgaggatt tactcaaact
    96601 agaagttgga gatgtaatag taacaaataa aaaaataaat gattatatag atatatttgt
    96661 agaaaattca aaatcataca cagcaacacc aggatttata tcaagtaaaa aaggtgtaaa
    96721 aataaatgat gctgttggaa aagaggtgta gttatggaca atagtaatct tatttcagat
    96781 gaagaagcaa agatgttatt aaatgataaa gttgaaagtg aagttgatgg agatgatgag
    96841 ttagccttag atgtctctga agttaatcga aataatatac aaaggatact tgaccttaag
    96901 ttagaattat ctgtagttat aggaagaact aagatgactc taagagatat tttaaattta
    96961 cataaaggtt ctcttattga actggatact ttggcagacc aagatgtgga aatactaata
    97021 gataataagg ttttggctta tggaaaagta gtggtggtag atttaaattt tggtgtaaag
    97081 ataacaagta tagtaagtga agaagacatg gtaaaatctc ttgtttagag ataacatcaa
    97141 ttaatactta aggcatgagg tggtacttat tttaaactta aatgatataa aaaaagatat
    97201 actaaaactc aataaaaaag actcatgttc tctatataat gaatctatta ataatataaa
    97261 taataattgt atatcaactg gattaaaatt tttaaaacaa gcaagagatt taaacccaga
    97321 tgatgttgat atattaaatc tcacaggtct tgtaaactta ctaaaatgta attttgatga
    97381 tgctgtagaa agtttctata agagttcact ttgtgaaaaa actgctctgt gtgaaaagta
    97441 tataaacatg cttacatctg aggagttttt aattttcttt gaaaagtaca atcaacttat
    97501 aaggttaata aataaaggaa tgtataaaga agctatacaa gggtttaaac ttataactga
    97561 ccaatactgt gatttaatag aaccttatga gttgcttgcc ttactgtatg acaaggaaga
    97621 agaatatata aaatttgatg aatgtttaga agtattgaag attattgata aggaaaatta
    97681 tttattaaat caagaaaata acacattata tatgtataat agtgctaata tacaaactaa
    97741 aagtaatata aaagtagatg attataagaa tgagttctta cataaaagta gtagtaacca
    97801 taaaattaat gattataatg atgtaactaa agaaaagagt tcaagcaaaa accagaaaag
    97861 ttcagattct aataagaaaa aaagtattaa aaaaaataag tacctatata tagccataat
    97921 attaggaata ttattagtag gacaaagtat atatagttct tataagatga ataatttaac
    97981 tgataaaata tctaaaaata atgaaactaa aaatgaagag tcaatagatt ctaacttgac
    98041 taagaaagaa aataatatag aagaaaatga agatatgagt aaggcttcta atataaataa
    98101 gagtaataaa aacattaata aagaggatga tgtaaaatct aaaaaaaata ctgtagaaaa
    98161 tgaagatgat aaagattctg acttatttac agaggatgaa ttgatgtcta aggcgaatac
    98221 tttaaaatca gaaaagaaaa ctaaatcttc tatacaacta tataagaaag ttgcagatat
    98281 aggtgaaaat aaagggaata catctgaagc aacttatcaa gttgctattc tcagtgaaaa
    98341 gttaaaagac tataaaactg ctgaagaata ttataaaatg tatgtagaaa attactcaga
    98401 aaaagatgct tattttgatg aatcttatta taatttaggt atgatgtact ataacaatgg
    98461 tgatttaaaa aattctaaat tgacattaaa gaagttggtt aataaggtac caaatagtat
    98521 gtataataat tcaaaagtaa aagaaatttt aaaagaagaa tagttaaatt agataagaaa
    98581 aataaattat tttattttaa aataatatga ttataatata ttgacatacc attttaaaaa
    98641 atttaaaata ttaattataa aatgaggagg gataaaaaat ggaatttgaa aaagggagta
    98701 tttcaattca tacagaaaat atttttccta taattaaaaa atggttatac tctgataaag
    98761 acatatttat aagagagctt ataagtaatg gatgtgatgc agtaagtaaa cataaaagac
    98821 ttgtatcact aggagaaata tcagaaaata agtcatcaga ttataaaatt acagtatctg
    98881 taaataaagg agaaggtaca cttaaattta ttgacaatgg aattggtatg actgaagaag
    98941 agataaaaaa atacataaat caagttgctt tttcaggtgc tgaagatttc tttaataaat
    99001 ataaggataa aatggaagag tcaaatgata taataggtca ttttggatta ggattttatt
    99061 ctgcatttat ggtgtctaaa aaggtacaaa tagatacact ttcatataca gaaggagcga
    99121 ctcctgtaag atggatatct gaaggtggta cagaatacga aatatctgaa tcagatgcta
    99181 gaaatgatag aggaactact ataacactat ttattgatga tgatagtaaa gaatttttag
    99241 atgaatttac tgtaagagga ataataaata aatactgttc tttcttacca gtagaaatat
    99301 atttagaaga tgttgaaaga ttagaaagag aagctaaaga agcagaagaa aaagctaaaa
    99361 aacaaaagga agatggaaaa gaagagattg tagatgcaaa agtaattgag cctttaaacg
    99421 acactaatcc tctatggtta aaatctccaa aagactgtac tgatgaggag tataaagagt
    99481 tttatagaaa ggtattcaat gtatttgatg aacctttatt ttggatacat ttaaatgtag
    99541 attatccttt caatttaaag ggtatacttt acttccctaa attaaaaaat gagtttgaac
    99601 tgactgaagg aaaagtaaaa ttatacaaca atcaagtgtt tgtggctgac aatataaaag
    99661 aagttatacc agaattttta cttttattaa aaggagttat agactgccca gacttaccat
    99721 taaatgtatc aagaagtttc ttacaaaatg acagggatgt aagcaaaatt tctaaacata
    99781 taattaaaaa agtagctgat aagttgaaat ctctttgtaa aaatgaaaga gaagaataca
    99841 ataagttttg ggatgatata caaatattta ttaaatatgg ttgcttaaaa gatgaaagtt
    99901 tctatgagaa ggtaaaagaa tgtatattat tcaaaactat tgatgatgag tatataacat
    99961 tacaagatta tttagaaaaa tgtaaggaca aacatgaaaa taaggtattt tatgtaagtg
   100021 ataaggaaca gcaatctcaa tacattaaac tatttaaaga atacgactta agtgctgttg
   100081 ttttaaactc atcaatagat actcatttta tttcatttat ggaatataaa gagaatggag
   100141 ttaagtttaa tagaatagat gcagaccttt ctgatgtatt aaaagataaa aatgaaaata
   100201 aagatagtga agaaaacaaa gaagagatag ctaagataga aggtctgttt aaagaagctg
   100261 tcggagaaag agtgaagaat tattctgtag aaggattgaa aaatgaagac actccagcta
   100321 tggtattagt atcagaacaa tctattagaa tggcagaaat gcagtcaaga tttgctggaa
   100381 tggatttagg aatgaatttt gaggaagaaa aaactcttgt aataaatgag aacagtccaa
   100441 taatcaaaaa attggtttct cttaaagatg atgaggaaaa gaaagataag attacgctta
   100501 tttgtaacca gatagcagat ttagctttac tttctaataa agaattaaag ccagatgagt
   100561 tagattcatt tgtacaaaga agtaataagc ttatgagtct tttgatagaa ttataagatt
   100621 gaatttgaat acattgaagc aaatttataa aaagtattca atatcagtga taagaaagaa
   100681 gtgtctcaaa atgaactttt cagttcatga ggcgcttttt ttatgtgaaa ttaaatttat
   100741 tttaatcatt tcaacaatga aaaatatatt tatctctatt ttgagacaga ccattcttta
   100801 tttttttatc tttggttaat tttaaatatt taagtaggtt ctaataaaaa actctattta
   100861 gttaaatata gttaacttga tatataataa gataatacat ataattaagt aaaagattgt
   100921 tttttagttt atgtttaaat acataattac actttgttaa aaacataaaa ttattactaa
   100981 agtagaaata ggaggtttta gaatgaattt taattataat ttgccagtaa atatcttatt
   101041 tgggagaggc agaattaatg atgtgggaaa agaagtatct aaatatggca aaaaagtatt
   101101 gatagtaaca ggtaaaaata gtacaaagaa aactggatta cttgataaaa caatagattt
   101161 actaaaagac tctaaaatag aatatgaagt ttttgataga gtagaacaaa atcctcttat
   101221 aactactata tattcaggag tagaaattat aaaatcaact ggatgtgatt gtgttttagg
   101281 tcttggtggt ggaagcatta tggatgctgc caagagtata gctttttctt ataaaaaccc
   101341 aggagattta aatgattata tatttggaat tagacaaggt gaagaagctt tacctataat
   101401 cttagttcca acaacatcag gtacaggtag tgaaggaaat tgttttgcag tacttacaaa
   101461 ttcagaaact aaagataaaa aatctataaa gaagaatagt atgtatgcaa aagcatcaat
   101521 aattgaccca gaacttatgg ttacaatgcc aaaacatata attgcatcag ttggatttga
   101581 tgcacttgcc cataatatgg aagcatatct ttctaatgga agaaaccctc ttgcagatgt
   101641 acaagctatt tatgggattg aacttatatc agaaaaccta ataaaggtat ataatgatgt
   101701 taatgattta gaagcatggg aaaaaataac acttgcaagt actattggag gaatgacgat
   101761 tggtacagcg ggtacagcct tgccacatgg aatggagcat cctgtaagtg gtcttagaga
   101821 tgtaatgcat ggaaaaggac ttgcagcttt gactcctact attatagaaa gttcatggga
   101881 tagtgatatt gaaagatttg gtaatatttc aaaggtatta ggaggaactt gtgcagaaga
   101941 ttgttcagat gcaattagaa atttccttaa aaaaatagat ttagatataa aactaagtga
   102001 tttaggtatt gaaaaatcag atatagattg gttaactgat aattgtatga aaatatcagt
   102061 tgcaaatatt aagagacatc caaagtattt taataaggaa caaataaagg aaatgtacca
   102121 taagtcttta taatttgact ttacatattt agttttatat aaaaattata aattaataat
   102181 aaaaaattat aagtaattaa tagtaaaaaa attgtgtata gaagttatat atataataaa
   102241 tttgtcttaa gcttttattt tactttctaa taaataaagg agtttaaaaa agggaagatt
   102301 aattaagtaa tattttataa aattcttcga tttaaaaact ttaagtagag gtgaaataaa
   102361 tgtttaatcc caaaagaata atattcgaaa aaggaacttt agacactgat gtgggtaaaa
   102421 aaatatacaa taaatttaga gataataaag atgtagagat aattaatata tcatcaaata
   102481 ggattaaaga acatattcca ggtgaaaatc tatatgaaca atatagaagt gggaagcaga
   102541 ctatggtagt tgggattaga aaaagtctga agtttcaaac atgtaaacct tctgctaatt
   102601 atcaactacc acttgtcagt ggatgtatgg gaagatgtga gtattgttat ttgaacacac
   102661 aattaggtga taaaccattt ataagggtgt ttgtaaatgt agatgaaata cttgaacaga
   102721 caaaaaaata tattgaagat agaaagccac aggtaaccat atttgaaggg gcagctacat
   102781 cagacccagt tccagtagag ccatatacta attctttaaa gaaaacaata gagttttttg
   102841 gaagagagga aaaaggaaga tttagatttg ttactaaata cagtgatgtg gatagcttat
   102901 tggatgctga acataataat catacagaaa tacgatttag tatcaatact cctagaatta
   102961 taaatgaaca tgagcattat acagcctctg caaataaaag aatagagtca gctgtaaaac
   103021 ttgctagggc tggttatcag attggtttca taatagcacc tgtgttttta tatgaaggtt
   103081 ggaaagaaga gtataaaaat ctgattataa gtataaaaga agctttacca aaggattttg
   103141 ataaaaaaat tatatttgaa gttatatctc atagatatac aactaaagca aaaaatagaa
   103201 tactagagat ttatccagat acactattgc caatggaaaa tgaggataga aagtttaaat
   103261 acggtcaatt tggatatggt aagtacgtgt atgataaaga acaattagat gatatgaaag
   103321 agttctttct taaggaaata aatggagtat ttaaaaatag tttaataaaa tatataatat
   103381 agcaaatctt acctaaagat ttgctatatt ttatttttat acattttatg tttataataa
   103441 agcaatgaga tttagcacta tcatataaga aaattaaaaa gggcactatc tatcaagaac
   103501 attttttcta gttttgatac tataaaggat aagagtaaca aaaatatcag gaggagttat
   103561 agtatgcatg catgggagtc tattcaaatt acattggatt taatagaagc aaatttatca
   103621 gaagaaatat caattaatga attagcaaat aaagcaaatt tatcaccatt ttactatcaa
   103681 agactattta aaagattggt aaataagact gtaatggagt atataaagct tcgtcgtctt
   103741 gcaagagctt ctgaatactt agcagaacat aagaatcgta tacttgatgt agctttaaat
   103801 tttggatttg ctagtcatga gacatttaca cgttccttta aaaaagcata tggattaact
   103861 ccagaaaaat atagagcaaa tccagtaaaa ctcaatcact ttattaagcc agaattaatt
   103921 ttaaattatg ctatggttga tgaaggtgtt ccactgattg cagatgatat agtgattgaa
   103981 gtcaatcgta agacattgag taatccaagg acatttgttg gaatagaaat agaagtacct
   104041 atttgccagt tggtgggcgg tgaaacaact ggaattgcaa tagtagagga attatggatg
   104101 aaacttggaa gtcaaagaca taatatacca aatcaaattc caggtggaaa tgaatttgct
   104161 gctctttata tgggaaatgc aaaagaagga aattgtatgt atatggcagg tgtagaggta
   104221 gagtcaggta catcagtaga aggatatagt acttttgagt tgccagctaa agaatattta
   104281 gtatgtggat ttgaggcaga aaactttaat gagttagtta attcagctgt ttttaaagca
   104341 gataaattta tggaaagatg gatgaagaaa cataatttaa caactactga ttttgcaatt
   104401 gagatgtatt accccactac acctgaagca gcatatctgg aacattggat tgttccggtt
   104461 cctattgaac aatagaaagg atgatgaata tgaattggca agatgcgttt tttcaagata
   104521 ctaaacctac atttgagcaa attaatgaat ttattaataa tccattatgg gacaagttaa
   104581 ataaaacttt ggtttctact tataatgtag aacctaagct tgaatacagt aaatgttcaa
   104641 tgcaaagagg ttggaatgta aaatataaaa aaagaggtaa atcactatgt actttatatc
   104701 cacaagaagg ttattttaaa gctttggtta ttgtaagtga aagcaataga gtagaggttg
   104761 atttatttat taatacttgt tgtgattata tcaaaaaaat atataatgag gtaaactttt
   104821 ttaatggaag taaatggcta atgattcaag tagatagttt attggtatta aacgatatgc
   104881 ttgaactaat taaatttaga gcttaacata tagaacagga tgaatatata agtcatcctg
   104941 tttttatatt caatcagata aattaatata tagtctataa tatgaataat ttagtaaatt
   105001 taaatttact ttatctttct acattctttg caactaagtc cacatgtgtt tttttcttgc
   105061 atattagtag caccccaatt agcaaattgt tgtaaaatag gcacaatact tttaccttta
   105121 cttgttaatg tatattcaac ttttggagga atttcattat attgtttacg atgaacaata
   105181 ccagtagact ctaaatcttt taatgattga gctagcatag tatttgtaat gccatccaat
   105241 tttcttttta tgctactata tctaattgga ttttcaactg ctaacataca tataataggt
   105301 aatttccact taccaccgac aatgtctaat gcataacgga ttggacaggt taattcttca
   105361 acgtttttag ttatattttt ttcagtattt atactcattt taattactcc ttagttatag
   105421 tagtatcttt tttatacttt atcagaaaaa actgcatact tgttttttct gtattttata
   105481 ttaaaattat atcaaaggat aatccttaat acaagtattt aaaaggggtg taagaattat
   105541 gaaagcatta gaatttttga acaaggcacg agtttattat ttagcaacag ttgatgagaa
   105601 caatcaagca catgtgcgtc ctttaggatt tgttatggaa tacaatggta aacttacatt
   105661 ttgcacatct aatcaaaagg atatgtttaa gcaacttatt tttaatccaa aggttgaact
   105721 ttgttgtata gaccaaaacc ttaatactct acgtatttta ggtgaagcag tatttgttac
   105781 atcaaaagaa acacaagcta aggcacttga aataatgcca agtttaggtc agatgtactc
   105841 tgtaggagat ggtaagtttg aaatattctc tattgataag gcaaaagtta gttgttgttc
   105901 aatgagtggt aaaaagattg atgtagagct ttaattataa ttgaatcgac atccatagtg
   105961 aaaattaaga aaacgttatt actgaaatgt tgatagattt aatttaaatg caataaaaag
   106021 atttttaaat aatgaatatg taaaaatttt tagttattag atgtgtattt caataatgat
   106081 atactatttt gaataattac atactagaaa taagataatt aaaatttact ttataatggg
   106141 atagatttct tttaaaaaat attttaacta taattgattt ttatttaatc tgaaaaaaat
   106201 attatgacta taaaaaat
//
LOCUS       DAEPKC010000004        77268 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.004, whole genome shotgun sequence.
ACCESSION   DAEPKC010000004 DAEPKC010000000
VERSION     DAEPKC010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 77268)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 77268)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..77268
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.004"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            146..730
                     /locus_tag="KR294_000350"
     CDS             146..730
                     /locus_tag="KR294_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc dependent phospholipase C family protein"
                     /protein_id="HBH0238467.1"
                     /translation="MLMNTHFIMAKSILDNIDENKTFFISEKNFIYGNIKPDAFSKYK
                     LKKHYLDESFNMIVSKINYLCSLNIDSLSKYFSVSRLSQELGVICHFLCDFFCVAHSE
                     RWEFKHSLNKHVTYERELGAFAKDVDLSKIKCGTINSSFEKFFTKLYSDYKKKTDYMN
                     DLKFSAYTCNSVINYILDSILSNTIKSYHIANCG"
     gene            complement(834..1613)
                     /locus_tag="KR294_000351"
     CDS             complement(834..1613)
                     /locus_tag="KR294_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBH0238468.1"
                     /translation="MIKHIFCDLDGTLYENGTITKEDIVAIEEIEKKGVQFNVATGRI
                     FKQAHNIIKDSLDMNGYYVCENGSFIYDKDYNVIFKRTIDDNLVKKVIDRFESSDAQL
                     YFKYKGDVIVGSDTTAFRHYSSDFIVDPDFEKRSSFDNLIGNIGVCSENLEELSRIEL
                     YLKSEFSEVLEIYFSGTYTLNIVPKSVSKRGSIEHVIKTLNVSPDEVATIGDSPNDIC
                     MLEGFKYSFAMSKAREDVKQSANYVVDSVKSAIDVIMEINS"
     gene            complement(1671..2927)
                     /locus_tag="KR294_000352"
     CDS             complement(1671..2927)
                     /locus_tag="KR294_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011591286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HBH0238469.1"
                     /translation="MKAEIISVGTEILLGDIVNTNSQFLAKELASLGIEVYHQSTVGD
                     NKQRLLECFDESLKRSDFVITTGGLGPTGDDMTKETAAEYFGQKLELHKPSLEVLESF
                     FVKTGKKMAENNMKQVYFPKDAIVLKNNNGTAPGAILKKDGKFIIVLPGPPREMKAMF
                     NESVKPYLQQFTNEMLVSKTLRLYGIGESNLELEILDIINEQTNPTVALYAKELEVTI
                     RITAKAENEREAFKLIKPVEEKIKSRVGKYVYTEGDISISEGETALEDAVSKLLVEKN
                     LTIAVAESCTGGLVSSSLINYPGISSVFLEGCVTYSNDSKMKRLGVKRETLEEFGAVS
                     EQTAIEMAEGVAKGLKANIGISTTGVAGPGGGTKEKPVGLVYTAIYINGKTIVKKNIF
                     NGDRRKIRLRATRDLLNELRIQLEKL"
     gene            3185..4084
                     /locus_tag="KR294_000353"
     CDS             3185..4084
                     /locus_tag="KR294_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HBH0238470.1"
                     /translation="MKIAVIMGGISSEREVSLNSGKEIYNNLDKNKYEVVKVIIDDKK
                     DIFTKIPEDIDFAILALHGKFGEDGCIQSILETMDIPYSGCGPLCSGMCMDKNITKKM
                     LRDSNLPTAPWVLVKSVDEIDYDEIDNIGYPVFIKPNSGGSSVATFFIHSKDEVEEAV
                     RKGLEVDEFVMIEKYIPGGEYTSFILNGEVFPTISIKSDSGFFDYEAKYSVEKGAKEE
                     VVYLDEELQKRVNEISETCWKIFNCKAYVRVDMIISEGIPYVLELNTLPGMTQTSLIP
                     RSAAARGIKYSELLDKLIEYSLN"
     gene            4108..5556
                     /gene="ddlR"
                     /locus_tag="KR294_000354"
     CDS             4108..5556
                     /gene="ddlR"
                     /locus_tag="KR294_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator DdlR"
                     /protein_id="HBH0238471.1"
                     /translation="MIFSNLKLNDNEPIYIQLKNYISDMISKGLIPDNSKLPSTRELS
                     QLLQVSRNSVVLTYEELKSEGLIYSISGKGTFVKSKNKSSNTTWSLNWDCLENTYSKK
                     ANELDIIKSEIPWSSDLISFKSISPDGDLFDIEELKKSFLNRISLEGHKLLNYGYAQG
                     YKPLIDYLLEYMTNKGADISNKDILITNGFTEGFDIIMSSFTQEKDYIICENPTHNTA
                     IKIMKSHNLNILGVDINEDGLDFNMLEDNLVKYKNKIKFAYITPSYHNPTGIVMTPEN
                     RYKFYNLMKKYNIAIIEDGFNEELLYNSSHIFPICSLDNMNNGVVYIGSFSKILFPGM
                     RIGWIFADKKVINKLESVKRCRNIHVSFLDQGILFDYLSNGGFEKYIKKIRKFYGDKF
                     NFAYKCIKKYIKTEYILGDGGLHIFIKLKNIDTRVLLEKCYEKNVIFMPGDLFFTDNS
                     GFDTLRLGFSRLSFEDIEIGIKIIGETINEMF"
     gene            5615..6421
                     /locus_tag="KR294_000355"
     CDS             5615..6421
                     /locus_tag="KR294_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HBH0238472.1"
                     /translation="MNLILGDNMSKKSKRRKINKLKLTIVITVLFLALLSIYEILFSN
                     PNKKGNIKSQETMQNKNNTTDDSKNNQSSTKKQEDNNIKPTFSYSSIPDNIKNKMIGK
                     SMPTDEPISFDSLSYLKLTYYGFDEKTHQGEMIVNSELAPEVVDIFKELYEKKYPIEK
                     IKLIDDYDAVDEKSMSDNNTSSFCYRTIAGTNVVSNHGKGRAIDINPLQNPQVSGNDV
                     TPKVSTVYADRSSTKFGMIKKGDDCYNAFVSRGWSWGGYWKNPDYQHFEK"
     gene            6447..8366
                     /locus_tag="KR294_000356"
     CDS             6447..8366
                     /locus_tag="KR294_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_071223118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBH0238473.1"
                     /translation="MNLMTLENISKSYSEKKLLENISLGINEGEKIGLIGVNGTGKST
                     LLKIIAGVEESETGNITKTNGIRIEYLPQNPTYNENSTVLEQVFNGTSEELKLLGEYQ
                     EILEKLNSNFTEELNKKLLSVHEKIDALNLWDLESEAKSVLTKLGINDFNQKIAELSG
                     GQRKRVSLASALITPCEFLILDEPTNHLDNDTIDWLEEYLNSRKGSLLMITHDRYFLD
                     RVTNRIIELDKGRLFSYDGNYSIFLEKKMERLSLEASIEDKRQNLIRTELAWVRRGAQ
                     ARSTKQKARLQRFDELINRDSFKPDENLDISVASSRLGNKIIEIHNISKSFEENTVID
                     NLEYTLTRTDRIGIIGKNGMGKSTLINILNGEIEPDSGYISIGETVKIGCFSQDDSHM
                     NIDMRAIDYVKEASDYIETSDGTRITASQMCERFLFNGTMQYTLIGKLSGGERRRLHL
                     LKILMTAPNVLLLDEPTNDLDIETLKILEEYLDEFKGVVVTVSHDRYFLDRICNKIFA
                     YEGNGKIHIYTGNYSDYLIYREIQGIEFEESKKESVKKDDSTTLKKEKPKNDKKLKFS
                     YNEQREFENIDSDIEKLESKIATLDESTAKFSTDFTKLQEILDEKSKLEKELEYKYER
                     WEYLNNLADEIANNK"
     gene            complement(8608..8955)
                     /locus_tag="KR294_000357"
     CDS             complement(8608..8955)
                     /locus_tag="KR294_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PqqD family protein"
                     /protein_id="HBH0238474.1"
                     /translation="MSKSNDVLDIVFKITDGLEYEVAENRVVTILEKQDHKIQKFFRK
                     LKARIPKYKKIELDEYSSFVFLQIDGQRTVREIGKNLEAKYGEESHPLYERLLVFLNH
                     IEVNCHYIERLDI"
     gene            complement(8942..10870)
                     /locus_tag="KR294_000358"
     CDS             complement(8942..10870)
                     /locus_tag="KR294_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide transporter, OPT family"
                     /protein_id="HBH0238475.1"
                     /translation="MNKKLPKGAYGEVSGKDYVPYITDKSRTGGNVAVLIIGIILAAI
                     FAASTTYSGMKAGLTVAAGIPGAIIGSAFVGAFARSKGILGKNLIQGMSSGGESVASG
                     FIFVLPAVILIGSQITFFEGLAVGVGGVLFGIGIAAIVHNYLIVEEHGKLMYPESMAI
                     SETLVASEAGGDSIKYMGIGFVISGFITVLTGSFLNVANNVMSLVGSKFYKWKFDIEV
                     NPLLLGIGFIVGLEVSLTMFAGSILSNFGIAPLIGYFTDMAKDGAMVWNNPAMPLNQM
                     DVGAISSSYVKYIGAGMMLCGGIIGAIKLIPTIIASIKETLKAKSSAGEGEEGSSIQM
                     ILLLGGVVIGFLAAFLISGNIVMAIIGAIISLLLSLLFVIVAGRLTGTIGTSNLPVSG
                     MTIASLVIVTLVFVIMGWTDLEANKSLLLFGSFIVVAIAIAGGYTQSQKVTYIIGGSK
                     NEMQRYFTIASIVGVIVVVGVILLLSDQLRATGDNVQFALPQANLMSTLTSGIMSGSL
                     PWVMIIVGVFMAIVLYALNLPIMTIAIGFYLPIATTSIILVGALIRLFVELVSKTEKE
                     KEVKVSNGISLSSGLVAGGSIIGLIGIILQVTGVVTPKVPSGFAATNSMAIALLVVLV
                     VLTALPIVLSKVKNNEQE"
     gene            complement(11281..13470)
                     /locus_tag="KR294_000359"
     CDS             complement(11281..13470)
                     /locus_tag="KR294_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid adenylation domain-containing
                     protein"
                     /protein_id="HBH0238476.1"
                     /translation="MYEVNLERAMNYWMDLLDDYTNIAKIPNDFFYKDCSDEVVDEVF
                     KMNIEKHERLIQYSKVNNISIDSIIETIYGLILQKYIYEDDVVFGKTMNIIPIRVRVR
                     QSEKFIDVVRKLKRQWSRSLEYGYYLLSDIENKNHLNTKLINTIFIAKSFDLSYDYDI
                     EKKGYDLSVIVYTKRALKIKIKYKPSIYKRETIRRILNQFDYIIEQIIEDNDILIEDL
                     EFVCKEEEKVLLEDFNNNQYEIPYDKSYVDLFREQVKVTPSNIAARDENRKLTYKELD
                     EVTDKLAGYLNHIGVESEDIVAVMLPRDINIIITAIGIMKSGGAFFPIDTSNPEERLN
                     YLLEDSNAKVVITTDELKSKVVNENTIVLDINDEEMFKLGYELTEKITSSNCAYTIST
                     SGSTGRPKTIAIEHKSLVNMCYYSVKSISATENDICGIYLSFSFDAVMKQLFPYLLVG
                     ASIDIMPEEAKFDEYTVNEYCEENDITILALPTAFARLFIQNCNNNSLRVVQTGGERL
                     KGYRKRNYELYNEYGPTEFTVVSTSFHVDREYGKIPIGKPIFNTYAYVLDKKNKLCPI
                     GAPGELCLSGIQISRGYLNKKGLTEQVFVENPYKTCEHNKLMYRTGDLVRWLDDGNLD
                     YIGRMDNQVKIDEFRIELYEIENIINNITEIKSVVCISRTNDDGDMYICAYYVIDEED
                     SGKINERTIREYLNEHLPPYMIPTIIMRIDKIPVTPIGKVNKRALPE"
     gene            13801..14532
                     /locus_tag="KR294_000360"
     CDS             13801..14532
                     /locus_tag="KR294_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HBH0238477.1"
                     /translation="MNIYAHRGFSGKYPENTILAFKKCLDMDIYGIELDVHRTKDGKI
                     VVIHDEKVDRTFNGHGFVKDFTLRKLKTLNSSFEGYQSNKECKIPTLEEVLILISPTD
                     LILNIELKTDKINYPNIEKDVLELILKYNMKNRVLISSFNSNSLKNFHKLDPSIKTGL
                     LCYLPINNVVNFAKFLGNSYLHPPLVLVNESLIELCHKNLLGVNVYTVNEEGDILHCL
                     KLNVDGIFTNYPDIASNLLHSKQYS"
     gene            14612..15247
                     /locus_tag="KR294_000361"
     CDS             14612..15247
                     /locus_tag="KR294_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBH0238478.1"
                     /translation="MDNLLNELEALKSNLDNLPIEKIENYDLSKTALFIIDVNNGFAR
                     QGALYSPRVESLIKPIEMFTKKISNKLNRVIAFTDSHTPKSIELLSYPVHCLENDVES
                     ELVDELKSIENLQILPKNSTNGFFALENLDFDNIDNIIIVGDCTDICIYQFAITLKSY
                     FNQHNIEKNIVVPMNLVDTYDIPNVHPAEILNLVFFNSMIQNGVNVLKEIR"
     gene            complement(15498..16091)
                     /locus_tag="KR294_000362"
     CDS             complement(15498..16091)
                     /locus_tag="KR294_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3867 domain-containing protein"
                     /protein_id="HBH0238479.1"
                     /translation="MSDDRIIDFNELKNKVKDSDVDKFEQYIYNLYFSVMDGKMSMAE
                     FSRKIFDYMRDNNISQEKFMKIQKQFMERYGMDTEEVEKQLRNFGIDPSTAGFMSNNT
                     SSKVSTEDLESFKKSAGFYEKYGEKIQPKSCITTFIKNDLNDINVIIDQEKIMLCSDR
                     KINLMDSELNEFLLEYKNMFNKKIKVVMCETTNKYDY"
     gene            complement(16162..17025)
                     /locus_tag="KR294_000363"
     CDS             complement(16162..17025)
                     /locus_tag="KR294_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HBH0238480.1"
                     /translation="MLGIIAPSGPLRNTSLEEIKFNLESYGYEVKFSESCSLNYKGYL
                     AGNDDIRARDIEDMFLDKDVDIIMCLRGGYGTTRILDKINYDIIKQNPKPFIGFSDIT
                     GLNLAFYKNCGLLPYHGIMAANVGKWGKFTYKSLVNALEFKDELYLENPKEEKIYTVC
                     EGKAEGIIMGGNLSLIIATMGTKYEIDAKDKILFIEEIGEPQYKLDRMLTQLYSSGKL
                     EECNGIIFGDFKDCIEENDLMELLIEFANKVNKPSIYNLQSGHCIPMITIPLGRMCEL
                     DATEKIVKLKK"
     gene            17188..18357
                     /locus_tag="KR294_000364"
     CDS             17188..18357
                     /locus_tag="KR294_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH0238481.1"
                     /translation="MLNIKTLCHEINDWVINIRRDLHKTPELGLEEFQTKKKIIKYLN
                     EIGINYIEYKNHTGITAYINVSPNFETVAIRADIDALPITEELNYSYKSINIGKMHAC
                     GHDAHTAILLGTCNILFKLKDYLNVNVKFFFQPAEETIGGAQLMIEDGCLEKPNVKYI
                     FGLHVNPNINKNLIELKYNTLNASTNTLQLTVHGSKCHGAYPHQGIDAIVISAHIITA
                     LQTIVSRNTNPTDSVVISLGKIEGGIKENIVCDKVVIRGTLRTLTPETREFSKKRIRE
                     ICDFTCKTFGGSISVEIEEGYPALINSNHLVDYVKQNAVELFGEENIILKDSPTLGAE
                     DFSYFLRHCEGAFYHLGCANREKNITSPLHTSTFDIDEDCLITGVMLHVKNVLSF"
     gene            18458..18934
                     /locus_tag="KR294_000365"
     CDS             18458..18934
                     /locus_tag="KR294_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HBH0238482.1"
                     /translation="MKEILINPIGKICIQGEEVFIKLDKKYVPALNELDDFSHLNVFW
                     WADGFDNPELRSILETPKPYKSGPDVIGIFATRSPIRPNPIALTAVQIINIDHENGII
                     KIPYIDANDNSPVIDLKPYTPSVDRVENPSVPKWCSHWPKSVEKSGEFNWEDEIEF"
     gene            19500..20294
                     /locus_tag="KR294_000366"
     CDS             19500..20294
                     /locus_tag="KR294_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M55 family metallopeptidase"
                     /protein_id="HBH0238483.1"
                     /translation="MKLYLSADIEGTCGIVNWDETKLECEFSQHYRTQMSKEITAACD
                     GATQSGVHEILVKDAHDSGRNINPNILPENVKILRGWTKDPLVMMAGIDESFDACIFT
                     GYHSGATCNGNPLSHTMDIDYDYFKINDEIASEFTINAYIAAYYNVPVAFLSGDEMLC
                     ESAKKLNPNIVTVPVSKGIGNGSISIHPNLALKKIEKGVKKALSGDLSRHLIKLPDKF
                     KIEIKFREHYKAFKASFYPNMKKIDSQTVLFETEDYYEFLRMLLFI"
     gene            20318..20761
                     /locus_tag="KR294_000367"
     CDS             20318..20761
                     /locus_tag="KR294_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="regulatory YrvL family protein"
                     /protein_id="HBH0238484.1"
                     /translation="MIKISNKRRIPLGEFISVFLFFAVFFGITFCIFTVIGIGFLSFL
                     GFEYKSLGAVLIFFLIYFCITTPIDFLCTTILDIFRYVNKLPYSIYKLCEFIIDFILT
                     FLAMNIIDTFMDSVTIPLSTEILFALLSYLLSECMDFFDRDKKKP"
     gene            complement(20850..22136)
                     /locus_tag="KR294_000368"
     CDS             complement(20850..22136)
                     /locus_tag="KR294_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBH0238485.1"
                     /translation="MEKVKVAVIGAGNRGTYAYAPYIYENSDVCEIVAVAEPKKGRRE
                     LFTQKYNLDSKNVFETLEDFFKHDKMADAVIIATNDDRHYDVAKLALEKGYHVLLEKP
                     MSNSLDGLVHIDDLCDKYKDKIFMICHVLRYSPFYNKLKEIVESKKLGELVSIQYNEN
                     IGYWHFAHSFTRGNWRNSNETSPLILAKSCHDMDILLYLVGSRCKKISAFGSLKHLNN
                     QNASGEMAQNCLQCLVEKKCPYSAKRIYLEKDRSINRAVHINPTEENLLNILKTSPYG
                     RCVYRCDNNVVDNMVNILQFENGVTATFNLCAFTKENGRTIKLMFSHGEVGGDLNKNE
                     IRIKEFGKNEEIVMNPSNQQNMVEEYDRNLIAEFIKLVSNKELEKGRVAAKEAIQSHV
                     MAFAAEYSRVSDEVVYIEEFFDSAKQMTKEIEETIF"
     gene            complement(22354..23244)
                     /locus_tag="KR294_000369"
     CDS             complement(22354..23244)
                     /locus_tag="KR294_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HBH0238486.1"
                     /translation="MSSTIKSNRIKGIMFIIASALGFAMMSAFVKLAGDLPSFQKVFF
                     RNLVSAIIAFWLIIKHKGSLTGKKENLKVLLYRSIFGTLGVIFNYYAIDKLMLSDANM
                     LNKMSPFLVVIFCAIALKEKINVKQIGAIIIAFIGALFIIKPTFSVEVIPYLGGIAGA
                     VFAAMAYTCLRVLGDREDYYTIVFFFSVFSLVTVGPIAFAVYEPMTLMQLIYLLLGGV
                     FASLGQFGITLAYKYAPAKEISIFDYSNIIFSAILSIFLFNVYPDMLSVVGYLIVFSA
                     AFYMFLYNKKLDKLDKEKKK"
     gene            23536..23880
                     /locus_tag="KR294_000370"
     CDS             23536..23880
                     /locus_tag="KR294_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HBH0238487.1"
                     /translation="MEIKRYEGTGRMSRAVVHNNTVYLCGQTHAEGGVIEQTTEVLAK
                     IEDLLNKYGSDKQHLLSVTIYLRDMKDFEAMNSVWDAWVEKGFEPARACVEARLAREH
                     LLVEMSVVAATK"
     gene            complement(24039..26135)
                     /locus_tag="KR294_000371"
     CDS             complement(24039..26135)
                     /locus_tag="KR294_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CocE/NonD family hydrolase"
                     /protein_id="HBH0238488.1"
                     /translation="MIKFKLYISGLYSGNVIFDGDLLIEKLNPFTNKIESLKPISKEE
                     NTYYLNLTKIDLKSLFNNFDVYTKSLVNTDKDTVINNLGETHSKLNEYIWVQRNKKFP
                     LDIIIVDNKIVGFICLSRETCTILIMDGYEEYTVLKEWEKTHKNEEIYSIRFGGNYMI
                     DMKDGIKLSTDVYLPDFVDSAKKAPTILMRTPYGKENDKEIYYKYVQRGYAVVIQDVR
                     GRNESEGKWEPMIHEREDGDSTINWIVSQEWSSGIVGMLGASYLGYVQWAAASSGNKH
                     LKALVSIVTSGSPFIDIPRKGGAFVSGMLAWAFMVSRNKVDRSKMVRDDWDDVLNIRP
                     IENIPVEALGYRIEFLEEWLKRVEKDEYWDLMDWHLQKDKINVPALVVSGWYDDNSMG
                     TTEALDVIKDYEKGKRKAILGPWMHNSNTLRDINGISLGNSSLRYDLDYNYLLWFDKY
                     LKGIENNIDTTAPVEYYSVGSNKWKTEENWPIINKIDKSMYLISDGNANTSLGNGRLV
                     FDNDLEEKYDSYIYNPKDPSVQLIDMSENEVGVPNNYKDLEKRSDMLCYTSDAFSEEF
                     TVTGDIKLEFFASSSAKDTDWVIKIMDVDLDGNSIKLADGILSARFRNSFYKSEFMEE
                     GEIYKFTIITSKISNTFKVGHKIRLDITSSAKNFIFQNSNTTEGYNSIEYIEAKNTIY
                     HGGKYPSKLILPIENK"
     gene            complement(26148..27308)
                     /locus_tag="KR294_000372"
     CDS             complement(26148..27308)
                     /locus_tag="KR294_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF819 family protein"
                     /protein_id="HBH0238489.1"
                     /translation="MNTLFSNPGSILAVMTSMIALGFYLQRYKAIKSLGPALTIIIMG
                     IILSNLKVVPVSTELYGTISTYAIPISMTIMLMSVDLKEMTKLSREPLIAIFVAVLTV
                     SIMAFLFGLVFAEKISEGWKVAGMFVGTYTGGSANLTAIGTGLNVSRQTLAAANAADY
                     VIGVPTLIFMFALPAILKNSKKFKKLWPYHVEESELEDCQNEEFMESKEWSIKDIAWM
                     LAIGFVVTEVSTILAGYFNSSFSSAARILLVTTISIIIAQLKPVKKLKGNLDLGLFVA
                     LFFLCTIGFSVDIKEFLGSTFTITLYCFSIIFASFVFHLGITRLLKIKYQYVILSIVG
                     AIADGPTSALVAASAKWNSLVSVAVVMGVIGGVLGNYAGISVAYAIKMSLGL"
     gene            complement(27327..28394)
                     /locus_tag="KR294_000373"
     CDS             complement(27327..28394)
                     /locus_tag="KR294_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide epimerase"
                     /protein_id="HBH0238490.1"
                     /translation="MKITDIKFEKLRIKLKKPVVVSFGVIEYGESIILKIETDEGYCG
                     FGEAAPLAAVTGEVLDNVLSVLLMFKKELIGKDPLDIETIHTIMDGIIIGNTSAKAAI
                     DIALYDIKGKIMNAPLYKVLGGFDSKVQTDITISIDKPEKMAVEALERVKEGFRILKL
                     KAGINPEDDIEAVKLIREAVGESIRIRIDANQGWNVNSSINTIKKLEEFNVDAIEQAL
                     PHWDLDGTAYIRNKSNTKIMIDESLHSPIDAIKAIKKNAVDTFNIKLMKSSGIYPAIK
                     INNIAEASGVNCMLGCMLETRIGITAAANLIASKKNITEADLDSFMFCEELEGISGGF
                     VMDGDIMNLVNKPGLGIEVNL"
     gene            28746..29312
                     /locus_tag="KR294_000374"
     CDS             28746..29312
                     /locus_tag="KR294_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0238491.1"
                     /translation="MLGEKMRNIRKSKKKTLSDVSKLTDLSISYISQIERDAIEPSLS
                     SLRKIAEVLDTPLYMFMDDNNTDDLVIRKEDRVMMKFPKSEMFYEIVSPMPTTEFTPS
                     ILFVEFELKPESEDAKDYIYHASEEIMVVTSGVVDICMGEKVVRLNPGDSTFIKANVP
                     HKIINPSKDTIARGYGVISPPIWPIKSK"
     gene            complement(29507..30493)
                     /locus_tag="KR294_000375"
     CDS             complement(29507..30493)
                     /locus_tag="KR294_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-dependent carboxyltransferase"
                     /protein_id="HBH0238492.1"
                     /translation="MGFKVELGGFQTLIQDRGRVGYGQYGVSGCGAMDEYAHRVGNIL
                     VGNSEDEASLEVLMLGPTITFDEYTQIAVTGGDLGAKINGKEIQNWRSYQINPGDVLS
                     FRGVKSGARAYVSIAGGIDVPLAMGSKSTYTRAKIGGFEGRALKKGDYINTFIQEKDF
                     TINKKLSSKYIPTYSSEIVLRIVKGPQFDAFSNGEVEKFLSNKYKVTNEIDRMGCRLD
                     GESIKHLNGADIISDGISYGAIQVPGHGKPIIMLSDRQTSGGYTKIGNVISVDLYKLA
                     QAKPNDVVKFELVDIYEAHRLLREQEDKIQDIYKSMKNIRVVKAKVLNDIAV"
     gene            complement(30523..31218)
                     /gene="pxpB"
                     /locus_tag="KR294_000376"
     CDS             complement(30523..31218)
                     /gene="pxpB"
                     /locus_tag="KR294_000376"
                     /EC_number="3.5.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-oxoprolinase subunit PxpB"
                     /protein_id="HBH0238493.1"
                     /translation="METRYLISGDKAVVAEFGNEISEDINKKVISFMRAIEISNLKGI
                     VTEMVPTYRSLMISYNPLEIDFDSLIENLKKIEDNLESIVLPKPKIHEIPVCYDEVFG
                     IDIKNVASYNNLTVDEVIKIHTSREYLIYMLGFTPGFPYLGGMDERIATPRLEVPRTK
                     IYGGSVGIAGSQTGVYPIDSPGGWQIIGRTPLKLYDENREEQILLRAGDFIKFVPITL
                     DEFIEIEKNNLSI"
     gene            complement(31238..32458)
                     /locus_tag="KR294_000377"
     CDS             complement(31238..32458)
                     /locus_tag="KR294_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HBH0238494.1"
                     /translation="MSTKNITDKTKNKKDVGALIGAAFIMATSAIGPGFLTQTAQFTQ
                     DFGPNFSFVILITTILFIGAQVNVWRVIGVSGLRGQDIANKIIPGLGYLVAFLVALGG
                     LAFNIGNVGGAALGMNVMFNMNMTLGTVLSGLIAIFVFMSKNSNSLVDKITKFLALGM
                     IIIVGYVAISNHPPVGEAVSRMVKPENPKGLIFPIITLLGGSVGGYITFAGGHRLIDG
                     GITGEENIKEITKSSLLGILVATMMRVLLFLAILAVVSKGLQLDPENPAASAFKFSAG
                     AIGYKFFGLVLWSAAITSVIGAAYTSVSFLKTLNPFIDKYEKYFIIAFIAISTLIMAF
                     IGKPATLLILAGALNGLILPITLGIMLIASKRKDIVGDYKHPTWLLIFGLIVVLISAY
                     TGITSLSSLGALFA"
     gene            complement(32487..33278)
                     /locus_tag="KR294_000378"
     CDS             complement(32487..33278)
                     /locus_tag="KR294_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LamB/YcsF family protein"
                     /protein_id="HBH0238495.1"
                     /translation="MYKVDLNSDLGESFGTYKIGLDEEVLKYISSANIACGFHAGDPS
                     HMEKTVQLAKKNGVKIGAHPGFLDLIGFGRREMKITKQEAKDYTKYQLGALMAFASSN
                     GCNIQHVKPHGALYNMAAKDKELAMGICEAIYEVDKDIILLGLYNSEMINSAKEIGLR
                     FANEVFADRAYDNNGFLVPRNVEGAVIHDTKHAIDRVVRMVKEGTVETLTGEVIHIKA
                     DSICVHGDNPKAIEFVKEIRKRFELESIEVCPLENIEVCSSENIV"
     gene            33866..34495
                     /locus_tag="KR294_000379"
     CDS             33866..34495
                     /locus_tag="KR294_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH0238496.1"
                     /translation="MDKNYTMPIYQKIALDIANKIYTGEIQEDSVLFGRSVLAGKYNV
                     SPETIRRSVKILEDIGVVKSIKGKGVIVLSPDKASSFIKKYRDITNISSYKSTLYNLI
                     DTKSNLENEILDTINKILDYSNRLEIINPLVPVQFTINSNCKYIGQTAAQTKFWQNTG
                     ATIVAIKRGEELIISPGPYIEFLEGDILLVVGDQHIYNSIPMFLYENEK"
     gene            complement(34609..36123)
                     /gene="glpK"
                     /locus_tag="KR294_000380"
     CDS             complement(34609..36123)
                     /gene="glpK"
                     /locus_tag="KR294_000380"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HBH0238497.1"
                     /translation="MEKKYVMALDQGTTSSRAILFNKKGEIVKIAQKEFNQIYPKAGW
                     VEHDPMEIWGSQSGVMREVIETAGIRPEEIASIGITNQRETTVVWSRYTGKPIYNAIV
                     WQCRRTSEICDELKNKGLEESIKEKTGLLIDAYFSATKVKWILDNVEGAREKAEQGEL
                     LFGTIDTWLIWNLTRGKVHVTDYSNASRTMMYNINDLEWDEDILRELDIPISMLPLVK
                     PSSYVYGHTDERMLSGAKIPIAGCAGDQQAALFGQNCVEEGTAKNTYGTGCFLLMNTG
                     SNIVKSKHGLLTTIAWGVDGKVTYALEGSIFIGGASVQWLRDELKIIESAKDSEMYAN
                     RVEDTNGVYVVPAFTGLGAPYWDMYARGSILGLTRGAKKEHIVRATLESIAYQTKDVL
                     EAMQNDSKLKLKSLKVDGGASNNNFLMQFQSDILNVDIDRPKIVETTALGAAYLAGLS
                     VGFYIGRNEITSKWSVEKEFNPNMSEEKRCKLYKGWKKAVSRALSWEKEDELDI"
     gene            36367..36909
                     /locus_tag="KR294_000381"
     CDS             36367..36909
                     /locus_tag="KR294_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH0238498.1"
                     /translation="MPKILENVKEDILKVSRDMILEEDYSNISIRKIAQRCGISAGTV
                     YNYFNSKQEIIEYITKSEWDLLIRRIEYSNKNTEDYIKKLNIIFTEIRNFINKVHNIQ
                     YNDFLNTFETERFFEMKKHKDDFHEQLSNKVYEALEKESFFNNDKLVCNIIIKMFFSY
                     STYLHIEFEDLKPYIEKLIH"
     gene            36923..39415
                     /locus_tag="KR294_000382"
     CDS             36923..39415
                     /locus_tag="KR294_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH0238499.1"
                     /translation="MNHNTSIKNKDSNPKIFLVLTLYLLGIFMGAIDTGIVSPARTII
                     QNSLGVNEKTGIWMITIYTLTYASVIPISGKLADKIGRKYVYLVSIFLFGSGSLICGL
                     SSLFSNFYILLIGRVIQAIGGGGIMPIATAEFGTTFPENKRGMALGLVGATYGIANIL
                     GSSIGSTILSIFGTQNWKWLFFVNLPICLIILIGGVFCIKNNKSESKEKIDKLGTLML
                     ICIIVSLLYGLMNIDFFNFKNSIQDISVYPYLLTFIVLIPIFIFIENRAKDPILSFEY
                     FLNPRILIVLILSLIVGIGMMGMVFVPQYAENALKINAGSGGYFVAILGLFAGIAAPL
                     SGRLIDKFGAKKILLLGFSVSMIGSLYLVLIALKTNTVFSVCVSLIFMGLGMGFTMGT
                     PLNYMMLSNTRLEESNSALATLSLIRSIGTSISPAIMIGFIAHAGLSVQDNIMDLVGK
                     PSTPKIVQLEELENMIDDLKSDPEMAKNLKNVSIPNMNDTSNINMDMTGGKLPKSLLN
                     KVQSADTTNITNITKEISTTMFDEKVPSIITKIQKNVQKGIDGTQSGINGIEDGENKL
                     NSGIKGVQTGIDNMVKARAGINQGIDGVKKGIAGVDKGIKGMEQGLEKQDEAIKELTT
                     AYNKIPTTEKTPTDNENNSNEQNQSNTSNSESDDTKNDSTENKNNNSSENKPNVNEQK
                     ESLNAQIQQLKKTRDDLNTKLQKNKTQKNELSKKLRSMESQKKELQSKLNNSISQKKD
                     MEKSLDTMQQQKKSLQAVLAKTQEVKTEIPKAFDKSKLDYINSIENNRTKIENTLQST
                     LNSGFKQMYITVFCVNLLAFIILLFYKENKTR"
     gene            39836..40234
                     /locus_tag="KR294_000383"
     CDS             39836..40234
                     /locus_tag="KR294_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH0238500.1"
                     /translation="MDTLGKRIAYLRNSKKLTQRKLMDILKFENLGKYETGDRKPNCD
                     ILMSIADYFNVTTDWLLYGKEKVNVNSSVKEDKEDYLHVTNDEMTILNLYRQLNERDK
                     IKIEGILELKISEYKDLKKHSSNNNEDKMV"
     gene            complement(40451..40660)
                     /locus_tag="KR294_000384"
     CDS             complement(40451..40660)
                     /locus_tag="KR294_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0238501.1"
                     /translation="MCKLDSDGVIECCRAIDDFITALSNIKSLNMERLNTLTKYSSTC
                     SILLKEGNYEGCTIVYRKMLEELKT"
     gene            complement(40692..40901)
                     /locus_tag="KR294_000385"
     CDS             complement(40692..40901)
                     /locus_tag="KR294_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0238502.1"
                     /translation="MDARKKWIPFLGVQVKQRLIELNMTQRELAKKIGVNENYLSAIL
                     NGRRTGKKYKSSIYQLLNIEYSEDD"
     gene            41200..41619
                     /locus_tag="KR294_000386"
     CDS             41200..41619
                     /locus_tag="KR294_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0238503.1"
                     /translation="MDTLGERIVYLRKAKNLKQYELEEMLGCDNLSKFERNIRKPNYE
                     ILKSIAEIFNVSVDWLLNGDNLSHKSDLICDSSSNYPLNSINSNEIKLLNNFRKLNDY
                     DKAKIEGMIELKLHEYEKEKDLGKIEYNKNKDEKIDK"
     gene            41847..42302
                     /locus_tag="KR294_000387"
     CDS             41847..42302
                     /locus_tag="KR294_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0238504.1"
                     /translation="MGLRDKFAQSFARSKTMSGPEKKANEIMGKLLLKKAILPIVLMF
                     VIIIAGAMLKINSWVTLGINLVIAVGAFFYIRNSSKKYQNFKPYVGNLISLEKKGKKE
                     YVAIIKQGKLPVKLQIAYGGEDLEHVKKNQMVQISYNPDAKIAILVNRQ"
     gene            complement(42509..42769)
                     /locus_tag="KR294_000388"
     CDS             complement(42509..42769)
                     /locus_tag="KR294_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0238505.1"
                     /translation="MDKLITELSSLGAIGILCALLFKNTMQEKKEDRDMYKKTVENFI
                     ELSTQQQEINKNILVQMGIMKTDVEEIKEDVTDIKGMLQNGV"
     gene            complement(43032..43385)
                     /locus_tag="KR294_000389"
     CDS             complement(43032..43385)
                     /locus_tag="KR294_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0238506.1"
                     /translation="MFKFDKNKIEQIKQGRKVEMQYKDISDISIGQVKQDDDITNNFI
                     ANVEIYEMLLNQSSVNEASNISTFSVRKSGGESGMVEVYVALILRGKKTIEEVPAVIR
                     EQVRIRCKELEIPVE"
     gene            complement(43402..48723)
                     /locus_tag="KR294_000390"
     CDS             complement(43402..48723)
                     /locus_tag="KR294_000390"
                     /inference="COORDINATES: protein
                     motif:HMM:NF012632.1,HMM:NF024930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0238507.1"
                     /translation="MKRTKLLQRGNFFGDKNMVVDEFDEGYDNYDFINFFTGCCNYTF
                     GLKNNNILYGCGDNSNFQLGLGEDNTTRKLFTKIPNISTNIKKVACGESHAVILTSDG
                     ELLVAGINTDGQMGLGLEKVGKTVSTFEKVPEIKGVKDIACGLQSTYLLYNDGTLYVA
                     GNNLYGQLGLGTNGASANVNTFTKVDVDNVKAVFSYNKSAFIIKNDNKCYSTGFNNQG
                     QLGLGDKNNRDLFSLVSINDVKTIACGSEHTVLMTYNNDIYGCGKEKCFGNALQSSLF
                     TKIEEVNIKTIACGHGNTMLIDNKGTLKVAGNNDIYQLGIANYSENIDNSFIDLKNIV
                     AKNIFIGLSHSILIDSNNDSYCTGDNTYGQLGSFFDDMHIVEFKKMDSEKYSYSNYIN
                     LIKSEDKLTLLKEEMEIKDIELPLDIHSVRDVVFSPYCTLVILGNGDVYGLGNNRYKG
                     MGSDLPSQLNELTKLSISNVKSIVASKNISGGIFYIKNDDTCYYSGPNSNSIAGVLPS
                     NSDVFKKISIDNVKKVVINTDLSNWFSLIVTNNKQIYTSGKSSSYVNGLSNALISQYT
                     EISLSNVTDAYSSYNATFIVVDEKKVYATGINTNYLLGFSTSDGSNVNLGLLSDWYYI
                     NISGSSYSRVSCTNNITKINNIIIYEYVTVFCTNIGSFLTGYHGTSWTKPTDSSYRVQ
                     YQGISYAGYLDSYIYNYYPTRCTQSSSSTTFAYLYNGESSSNLKNVNPDNLLISGGSS
                     YIHQYGRNYLNNQSSNNIAASNINSGPITSDKAIFLYKALLYLSSNTLYGFGNISESA
                     KELDVSDTQDGYNATNYKKVMKNIKNIFIPPYDLSRDKTRFAILTDKSLFICGYNSKG
                     THGISVNSSLNLNNKINYNKKNSSSEISSNIQEIYSHSKSTYLLTNNNMLYSVGLNDV
                     GQLGVGDEINRKVFTKINIDNIKSINVNRFTDNSKHAFAIKNDNTCYAVGLNNSGQLG
                     IGDNVNRNIFTKINVENVKYVAVYGNTSLLLTNDGLLYGAGNNGKGQLGLGDTTSRNI
                     FTRIPINGVRDVYLCNDVSIIVKNDNTCYVCGLVNGYFGFTEGSISTFTKINIENVKS
                     VVTAGSEATFFITNDNMIYTTGKKERVFFSTETNDIKGIRVINNIINAKKIVVNGYTS
                     AILTNDNKLFVGGLSGYGSIANNNNTNSVEDVKDVFVTANNTLYIDNNNNLISSGRDT
                     YGISDESYRDMSVPYYKVSIKKDVDTVFSSYNTIFIKDIYGKFYSSTGDNRYNHLGIH
                     HRYDNDKNEALEGSLHSYFKTDNTSDKIVFNKKNEKLVMFNDKYIKTNNKYINYKNIF
                     KDNFKYTSIILPFEVSDIDISKTHSLAVAKDGKLYGIGSNSYKEINQTLEDIELLTLT
                     EVNISDVKKVACGDNYSYIIKTDNTLWSYGKNTEYQLGVGHNNDVRELQKVTGLPSVK
                     DISIYNSMTLVLTNEGELYAQGYNTNGLFGLGESEKDKIIRTFTKVLTNVKEIKSHND
                     DHILVIKNDNSLWITGKNKSMYKISISITDLYEFTKIPIPEHLNDILDIELSDDTIYM
                     ITKVDTSKASIEIVEKSISQVRVVVQDPNNVIEKLEMFINDELISTKTNLEINSIIFE
                     IPQNKIVLGENKILIKASSPTGDLYSSMFIFKSETGLKVKKDSILMINNKVYSIINIT
                     ENNTDLIVTLNEGLKDDMMENNPIYQLINKTKVQVKINKSDLFKDMKLVEIKKSDSSY
                     QEIYELEEANIKSAQPKIIVEKGDKWTAIKRPSMIFRYDAENNEPQA"
     gene            complement(48740..49723)
                     /locus_tag="KR294_000391"
     CDS             complement(48740..49723)
                     /locus_tag="KR294_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBH0238508.1"
                     /translation="MEEKFYIILTKIGREKIANATALGELVGLTKFQVGDSNGEYYEP
                     TEEQTALKNVVWEGNINSLRIDEKNPNWIVIETILPGTVGGFMIREAAVLDNENNIIA
                     IGKYPETYKPRAEDGSIKDLVVKMILQLSNTSNVTLEVDPTLVFVTQKDIQDLDDKFD
                     KNIKEIKVKIGEELLSTEAKNLSGAINEVVEKIKNISIDDVIGGQIQTELSVLKNSYN
                     KLSEKVLDILIYLELESEIDVDEAGYWYDTLTNAKNIIAIEGLKLDLNRKCITGELGS
                     VTFKNVVLPFNANRVRYIHEMDNNFVETKSNRAYSIGQTDITLNKYSYEIR"
     gene            complement(49724..50422)
                     /locus_tag="KR294_000392"
     CDS             complement(49724..50422)
                     /locus_tag="KR294_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2313 domain-containing protein"
                     /protein_id="HBH0238509.1"
                     /translation="MKLIDKLPSFDRNYIVEEIQGAYDTELNILKEDIDDTFNQLFVD
                     TATWGLDMWEDILCIEKKELDFDTRRSNIKAKMRSRGTSTIEVIKSICEAYTKSETDI
                     KVYSDEFTFVLSFIANNCDYKTLLDCSDMIERVKPAHLLHYLEPIILDKSMVYCGGGM
                     VCSEEVKVHPYFEPIIKCSAVVNCGAGMISREEIKVYPLSIKCIENNCKINIAIANDT
                     GVENVVVYPKSEVV"
     gene            complement(50419..51471)
                     /locus_tag="KR294_000393"
     CDS             complement(50419..51471)
                     /locus_tag="KR294_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HBH0238510.1"
                     /translation="MYSDQTYEVIKNRTLENINLDIYKGEGSFLNNMVSGNNLELSKI
                     YLELSKMHKMAFIQDTYNQFLDKRVNEFGVYRKLGTESNGEVEFIGEKGTVINNGTII
                     SYRDLLFVVIKDVTIGSEEGDNSPVQALEVGKKYNLPTNCEFKLVDNISGVTKITNTR
                     SFEGGTDIETDEELKERFYKIQRNQATSGNKAHYEEWALEVDGVYNVKVYPRWDGPGT
                     VKVLIFGKNNQAVDTETIERCQQHIDEEKPIGPTITVVTPLPIEISISAVMKLEDGYT
                     LDNVKESFLESINTYFRDIRGEIIYTKVMGILINTTGVHDLSNLLINGSTDNITINED
                     KIPSVTTVNFSEVENQ"
     gene            complement(51464..51892)
                     /locus_tag="KR294_000394"
     CDS             complement(51464..51892)
                     /locus_tag="KR294_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2634 domain-containing protein"
                     /protein_id="HBH0238511.1"
                     /translation="MSTIFPFIGVPEDYILPKTEELPIFREVAWDFEKDEPILEKGDF
                     KIIEKKEALKVWIYKCIKTNRYEHEIYSLEYGTELSELIGQKYTKGLTESEASRFIKE
                     ALLINPYILEVNVKSANFNRDILSANVKVSTIYGEVEINV"
     gene            complement(51892..52218)
                     /locus_tag="KR294_000395"
     CDS             complement(51892..52218)
                     /locus_tag="KR294_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2577 family protein"
                     /protein_id="HBH0238512.1"
                     /translation="MANPINEFIGIIREEGKYHNQPSFFIGKIKSKLPDLKIETNNII
                     LEKEDILIDSWMIDRQLETFDTETNQEHQHEVKNPFIDNFESGDMVIMFRIGEKFAVV
                     SKLVSL"
     gene            complement(52234..53763)
                     /locus_tag="KR294_000396"
     CDS             complement(52234..53763)
                     /locus_tag="KR294_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBH0238513.1"
                     /translation="MIINRSKDSSSNEISFVSKDMGFLLTQSEVSYNFKDKLVEDIAK
                     QVFAENRLSVGIIAKTNVKYTKMFIGVNGYDTIMSAYTEASKKTKKKYMIEANLDKFN
                     VIEKGTVTLSVMFEEGFNIINTTFSESMENVKNKVIVVDQYGSKISEKIDNEIFKEVN
                     VIMQKVIQQQENQDVDIDSEFNGIEKSCSLKGYGDVSCITGRGVKVKDSYTKLVGLFY
                     IDTDKHTWQNGEYQIELELNFQNLMDEKSAGQDEPKEESNLGGEDYAGGKEFTAEFTA
                     YCPRKEEGGDTDCRKKKLDPSKKTCAAPMVGKYEQTYYTKEFLNKHPLLNYGDEIQVI
                     TGVSGRDGVYKVNDVGPAITIEKNGTYHIDILFGNVEEASKFGRRKGKIIIGGYSGNV
                     SDKAKIVISEAKKHLGKPYKWGGNGPSSFDCSGLMVYCFKKVNVSLPRTSNQQSKKGK
                     KVEQKNLQAGDLVFFHNPVSHVGLYIGNGEFLHAPQKGDVVKISKLSSRRDFNTARRV
                     L"
     gene            complement(54045..54467)
                     /locus_tag="KR294_000397"
     CDS             complement(54045..54467)
                     /locus_tag="KR294_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0238514.1"
                     /translation="MEMWLRQAEDRFRFPVFPSSFSINGKAAVNSSSILKIGEIATFG
                     GVALKSISISSFFPNKDYTFCDYTGFPSPYDCVNKIEKWMKEGFILRFTITETNINME
                     VIIEGFSYEERDGTRDVYFTLDLKEYKRIKIPKVTPKQ"
     gene            complement(54467..56920)
                     /locus_tag="KR294_000398"
     CDS             complement(54467..56920)
                     /locus_tag="KR294_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0238515.1"
                     /translation="MGNVREEGINMYLTDNYTPKMNQIISVTDNFRRATVAVSLSTNV
                     MASSIKNSIGSASNRVNSLNSSLRKVQTTASSVSSTMTKLSSSINAVSGVIGSLNGSI
                     MRLAITIAMIIDYFNKLIQKKNEFNSNIMIILIFKAKSDEVEKTKNKLLGNLKKIGGK
                     IWNIVIKAKDMTKRVISSILGKLKQVEKRPYQGSINLKDMVSSAMGRILPKLMLFKNT
                     FWSGVIAIKDMASGIISKVFPKLRLFAGKVWSGAIAVKDMASGILGSIKGKISDLTNG
                     ATIGVAVKKGVDLLGQEQNQKVVLESVMKRNTGKVNQIDVDDYYGSLVRMANDTPFDP
                     EDVVAMGTKAKMISNITGGKKEKDITQAMVDVRALNMNTSSEQDVSAAFLSAAKGNME
                     SLNTLVGENYKTFDEALEGISVKQMGLAKEMSNTIPGIISGAQTSINNGLKSIVKPFD
                     DILGQGLKKIKTFIESGLGNLAGLSEKMAGKIGNVMNGKIIIGNKYDQMQSRSVKNGK
                     EFSDSTQYRISNEAEKRKMMVENKQERFENHAATMIGNAPKAIVNAGSTLLQNIDFTA
                     LIDSLLPVVNLVNNLLDSINNKSPIAQGLISIFGTIVTTAFQLIGPVVEAVSPIITRI
                     FTFLGEYAPQINNFIETLGVIWKTVWETLGPLLETGWKIIEPILGAFFNILDKVCKIV
                     KDICKWWQTMINKIKNGSITGTVLNLVEKSKKNYKDNPYAGTKAGDSGKAYSGKKGNN
                     AFGLNYVPYNDYQTRLHEGEMVLTKQEANQYRSRKNGGNINIAKLADTIVIREEADIE
                     KITSKLVASIQLAQLGGVL"
     gene            complement(56920..57087)
                     /locus_tag="KR294_000399"
     CDS             complement(56920..57087)
                     /locus_tag="KR294_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0238516.1"
                     /translation="MYYYWKKKGIRPSLFYAMDKGELKLIEAFFALEIEEEVEKMKHG
                     YGVCPLTGGGM"
     gene            complement(57114..57560)
                     /locus_tag="KR294_000400"
     CDS             complement(57114..57560)
                     /locus_tag="KR294_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBH0238517.1"
                     /translation="MSENGLSKNINIVDLLLNSDTENLERPSTIVELKRLSTIFGQEF
                     KVMCRALTISKDEEIQNTCLKIDENMKTDIDLPEMQMLTIIEGVCDLDGKLLFKNKEL
                     MDKFKAPTPKELARKLLLPGEITNLYRILQDVMGYGKNAVIEEVKN"
     gene            complement(57674..58102)
                     /locus_tag="KR294_000401"
     CDS             complement(57674..58102)
                     /locus_tag="KR294_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tube protein"
                     /protein_id="HBH0238518.1"
                     /translation="MANMEARNVMSGTWGELWLDGNKVAEVKKFQAKMEFTKEDIIIA
                     GQMGTDTKYMGYKGKGSITLYHVSSRMHKLIGEKIKRGSEPRFVAISKLNDPDSYGAE
                     RIAVKNIAFDDLTLADWEVGVKGEIEAPFTFTEYDFLDII"
     gene            complement(58116..59180)
                     /locus_tag="KR294_000402"
     CDS             complement(58116..59180)
                     /locus_tag="KR294_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath subtilisin-like
                     domain-containing protein"
                     /protein_id="HBH0238519.1"
                     /translation="MAIGLPSINISFKELATTVKERSARGIIAMVLKDAKALGLNEIH
                     EKEDIPVDLSAENKEYINLALMGNVNTPNKLLVYVIEGEADIQTALDFLETKEFNYLC
                     MPKAVEADKTAIKNWIIKLRDIDKVKVKAVLGKVVGNHEGIINFTTEDVLVGEKKYSV
                     DEFTSRVAGLIAGTPLSQSVTYTKLSDVVDIPKMTKVDAESRVNKGELILIKEAGAIR
                     IARGVNSLTELTAEKGEMFQKIKIVDTLDIIHSDIRKVIIDDYIGKVTNSYDNKCLLI
                     VAIKSYLEELEKSALIESDSTVEIDFEAQKSYLKSKGVDLSYMTLQEIKEANTGSKVF
                     LKAKIKVLDAMEDIDLSIEI"
     gene            complement(59185..59628)
                     /locus_tag="KR294_000403"
     CDS             complement(59185..59628)
                     /locus_tag="KR294_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0238520.1"
                     /translation="MLKYKEILETIIEILKKNFTESIFIDDESVQGSEGSCFFVSILS
                     VICTPVMLNTNNKDIVISIKYLPKPQSKSIRMYEISDELNKLFNRNIKVTDRKLNITK
                     LEQSIKKEESIYVLNFTFTLNYLDSVYEEDVVYENMKEINLNLGE"
     gene            complement(59877..60317)
                     /locus_tag="KR294_000404"
     CDS             complement(59877..60317)
                     /locus_tag="KR294_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0238521.1"
                     /translation="MENKKDILFKETDKRLHNYKYLDIKIKNINLDIKRCENEYSGCG
                     AMVYTEKTSNTYNISSSVENEVLKREERLRKLKMEKEDIEIEKEKIENALTCLNDIEM
                     EFFNLFYNSKTKNNMTYISMKLHLDRTSCYNLKKKMIFKLSEIL"
     gene            complement(60422..60619)
                     /locus_tag="KR294_000405"
     CDS             complement(60422..60619)
                     /locus_tag="KR294_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0238522.1"
                     /translation="MFKNNLKYYRKCKGMTQIQLARKAGITNDYISQIERGIKNPGLL
                     MAKKISSILEQNIEEVFFIQL"
     gene            60788..61108
                     /locus_tag="KR294_000406"
     CDS             60788..61108
                     /locus_tag="KR294_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HBH0238523.1"
                     /translation="MFAKRLRELRKEFGLTQRELGEKVGVSQRVLGYYETENRFPDEH
                     ILNKLADVFNVSVDYLLGRTLVKENIDTVAAHRKNPHEELPEEAQEQLNDYIEFLLNK
                     YKKK"
     gene            61190..61696
                     /locus_tag="KR294_000407"
     CDS             61190..61696
                     /locus_tag="KR294_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0238524.1"
                     /translation="MNNLDKLFELASQEEIIIHYTTYIAGDLEGLYINKHGIKIISLL
                     SNLKQNSKKLTSILAEELGHHFTSLGYYVSSYNDYYTKIIIDKCENKALKWACEFLIT
                     EEDIINIINSGITCVYEMADILNVDITFFQKRLEFLSLKKQSLQLGNNKYLILTNLPY
                     FYIFDPIS"
     gene            62397..63152
                     /locus_tag="KR294_000408"
     CDS             62397..63152
                     /locus_tag="KR294_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBH0238525.1"
                     /translation="MEKKVLATVGEKEITNIDIENALKSLDPYQAMQFKTEEGKKHLL
                     NDLVNQELFFLDAKEEKLDEEEIFKLEMKKIEENVLKQFAINKVLSSVNVTEDEKVKF
                     FEANKSSFSKPESATAKHILVDSDEKAKEILAQIKSEEISFEDAALKHSSCPSKDMGG
                     DLGTFGRGQMVPEFEEAVFSMAKGEVSEPVKTQFGYHIIKLEDLQESTESTFDEVKAE
                     VEKSLLYQKQNEVYGNKINALNAKYGNLVKYND"
     gene            complement(63295..63723)
                     /locus_tag="KR294_000409"
     CDS             complement(63295..63723)
                     /locus_tag="KR294_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBH0238526.1"
                     /translation="MNILFFLTPKSEVAYIYEDYTIRQALEKMEYHKYSAIPIISKDG
                     KYVGTITEGDFLWTLKNDLNLDLKGLEDVPVTDINRKMDNSPVSINADIEDLVIKSLN
                     QNFIPVIDDQDTFIGIIKRRDVIGYCYEIIRGYKNLANDN"
     gene            complement(64144..64344)
                     /locus_tag="KR294_000410"
     CDS             complement(64144..64344)
                     /locus_tag="KR294_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBH0238527.1"
                     /translation="MKTGVVKWFNNEKGFGFISVEGEGDVFVHFSAITGDGYKTLEEG
                     QSVEFEVVDGAKGPQAANVVRL"
     gene            complement(64527..65696)
                     /locus_tag="KR294_000411"
     CDS             complement(64527..65696)
                     /locus_tag="KR294_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase domain-containing protein"
                     /protein_id="HBH0238528.1"
                     /translation="MGGVALKILKNKNKYIKGIMAFVFLSLATTAGVFLINDLSMKNM
                     EEKVMESANVEGDDVKDQYKLLLENLFDYRNKAILEKNENILKGLYETDKKFGLWAYE
                     NEVKKMKYLENWSSKQGVKFKDIKTRVKIKKIKEKEKDLYGIICSVSTEYKYSYENQK
                     DKENAFRIGTYHYLNVKIIDNQYVITKEWYTDPFADSLNLENIKSDDIRNYIGQQDGV
                     ELQLTDEQKKAIDYAHKYCGAAADEEHGMKFNPNYRDYNPEGGDCANFASQIMFESGR
                     FKKNSIWNYSERAGTKAWVNAQAFKNYALYSGRGSLIAKGSYEEVYKEAYNLRPGDFV
                     GYEKKGRITHVSTVTGLDSRGYPLVTCHNTDRMLVPWDLGWSDKSIRFHIIKINY"
     gene            65932..66753
                     /locus_tag="KR294_000412"
     CDS             65932..66753
                     /locus_tag="KR294_000412"
                     /EC_number="2.7.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine kinase"
                     /protein_id="HBH0238529.1"
                     /translation="MQKKVAAINDLSGIGKCSLSVAIPILSALKVQCCPFPTAILSSQ
                     TGYPEFTFLDFTDEMVKYSNVWKNLKVNFDSIYSGFLGSKHQIEIVANFINDYPNAFI
                     VVDPVMGDNGVMYPIFTEEMRHEIKELVKHSDLTTPNLTEACFLTGNDYTKSDYNRDE
                     LIYIAKSVSDLGPSKVVITGILEDDNILNLAYDRDNDHVFFTSVKYNNCSYSGTGDIF
                     TSILCGMLVNKHDLGVAVNTATDFIYKTINYTSQFDTDRNDGVMFENFLSDLTNI"
     gene            complement(66829..68217)
                     /locus_tag="KR294_000413"
     CDS             complement(66829..68217)
                     /locus_tag="KR294_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase"
                     /protein_id="HBH0238530.1"
                     /translation="MLGGKKSNNKKVEKLRTIFIKYLSLFFIMTISIVLLLMLSFSVL
                     LSSGVILPANYAEKQFNKYKEQIISSEKVTEDIIPSIYEYGVYTLDGSLISGTFNKKE
                     SKEVWNLMRDIEERHAYSESYIKFFKKDEVFIIKYKIVSEYSSPILRAYLPKPETLGM
                     IIFSIIFFIEIVILSKVFGKKFNIEMELLKNTTEKIEQQDLDFVVESSKIYEINNVLF
                     SMDKMKLALKDSLEKQWMLEENRKEQISALAHDIKTPLTIIHGNTDLLIEINENPELL
                     EYMEYISKGVTQIEKYINTLIDISKTENGYILNKEAISMSEFIKDVLVQIEALASTKN
                     LDVEFYKQDNLPKNITIDRELLFRAIMNIISNAIDYSPSQSKLYISVSVRNKYLKFVV
                     TDCGSGFSKADLSKATEQFYTGDLSRNSKSHYGMGLYIVNNIVQKHNGILYIENSVKT
                     GGAMVTIEIPIV"
     gene            complement(68352..69110)
                     /locus_tag="KR294_000414"
     CDS             complement(68352..69110)
                     /locus_tag="KR294_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutG family
                     permease subunit"
                     /protein_id="HBH0238531.1"
                     /translation="MRQLIRIFCSDLIKLKRNFIILMHICIALMGMGLFLWYYKVSGA
                     DNILKIVAYLQVIAIAFPLLSGVVCSMFVEQEYYAGNYKHMLTTSNPKYLTLISKYII
                     LVCLGFVATLVSVLGFKFGISKAYFASSFYMISILILIGCNLFEYILHLFLSLRFGKG
                     TSIGVGIVEMLLSALLLTGLGSGIWQYFPCAWGVRFITIWSSFSSSKTVEYIKVESIK
                     AYQSTGLMCGFVTILAFVILCIWFSKWEGKKSEE"
     gene            complement(69112..69828)
                     /locus_tag="KR294_000415"
     CDS             complement(69112..69828)
                     /locus_tag="KR294_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutE/EpiE
                     family permease subunit"
                     /protein_id="HBH0238532.1"
                     /translation="MERFIRVEFQKMKGTFGMKLIWIVPVFCILLCGLGGGQNAAFNW
                     WYTTFLPGALTLISSLIVLKDEKSKYRGILPLPIEMKDVWTGKMIYCIICCFIASIIS
                     AIGVVFVGIIYKETISIGQNIIATILIILLFMWQIPLCMFLASKFGIFVTVLINMFFT
                     IVGVAVFSTTEMWYMFPYSIPSRLMAVVLHILPNGLPVPEGSEFLNNAVILPGVLISI
                     VLFVLFALATRVWFNNREVK"
     gene            complement(69830..70537)
                     /locus_tag="KR294_000416"
     CDS             complement(69830..70537)
                     /locus_tag="KR294_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic protection ABC transporter
                     ATP-binding protein"
                     /protein_id="HBH0238533.1"
                     /translation="MSNYILQVKGVSKKFKEQMAVDNISLAIKSNSIYGLLGPNGAGK
                     STLLKMITGILNPTSGKIMFEGHRWTRKDLSNIGSLIESPAIYENLTARENLKVHTTL
                     LGLPDSRIEEVLETVDLRDTFKKRSGQFSLGMKQRLGIAIALLNHPKLLILDEPTNGL
                     DPIGIEELRELIRSFPKQGITVILSSHILSEVEQVVDEIGIISNGVMGYQGEVSKEQN
                     LEKLFMKVVAENRKRGQ"
     gene            complement(70653..71189)
                     /locus_tag="KR294_000417"
     CDS             complement(70653..71189)
                     /locus_tag="KR294_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBH0238534.1"
                     /translation="MNKIAVSFLIIATTLLSTACMDYSISAVELVDSKESAVVKKDED
                     AKEETTSKMINSKKTTKIPIEIISKDEKIVKYLQIDEESSLKDKLRLILDTLSNEYFN
                     GLDMEVEVKEKDNLVKINLIEPDKKSRVSWKDDYLNEQNIIYTINNIIKNVIQEEDNS
                     IWIEEVEIYYNGKLIELR"
     gene            complement(71291..72361)
                     /locus_tag="KR294_000418"
     CDS             complement(71291..72361)
                     /locus_tag="KR294_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HBH0238535.1"
                     /translation="MNKKLAIFAAVLLVIGIIGTTWSGILVMPSLINFGLEKEAEFKK
                     ENKLYQEKVNIDKLDIAVDNINVTIKKSSSEDVRVTTRGNNEFYKYNVTLKDKTLVVK
                     GERKYENKIKKIKNFDQLLNTSINSMFSHDYREIIIYVPNNVDINASSISSHLFVYDN
                     VASNTITYKTSYGGFSRAITENKVNRLENLNLISNNNLHLSTKSILGVKNVNIESESL
                     YISSENEDVFINNIEEYIPENVNIKEKIGRNSNYESEFYLYSDMPIAKFLDIEVPNSK
                     VRLDIPVNKYKFNCDIKSKEAIEEFNNDEEYDNDSYDYEHSEEHSNKYRNTREIKGLL
                     NKNLSNLEKEYTIKINSNSLEL"
     gene            complement(72354..73412)
                     /locus_tag="KR294_000419"
     CDS             complement(72354..73412)
                     /locus_tag="KR294_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HBH0238536.1"
                     /translation="MNLNKTEFLEILKDYLKKDFSESEVNDILRDYEEYFVDGLIEGK
                     SDMEIIASLGSPKSIAKELILQTKEKNIEEEKIINTDVLNDKFSKFKSDMKKGYSILK
                     DEAKEKYSKSKENIDGKIMNTDILNGKFSRFKSNVKKDYSILKDEAKEKYNKSKENIN
                     DKLTPSIEEGVGGLSRQVIKGLLVVLSLFLIVPAFAFVCAIVSATIALVCSLIAFVIL
                     IPFVIKFIAMVPDVMMFCIFATIAFVGLEILAWQILLFAIKLGKQLLNNYIHWIKRKN
                     IYIKANEKMEKRKKATLNDEDLNKDINEDSYNNDYYNREEESIKETDEYNDDSINFEA
                     IYKDLEDIENKKGEDKHE"
     gene            complement(73399..73731)
                     /locus_tag="KR294_000420"
     CDS             complement(73399..73731)
                     /locus_tag="KR294_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBH0238537.1"
                     /translation="MNTQFRKGVLEICVLALISKKDMYGYEIVHNISKVIDVNEGTIY
                     PILRRLTKDLYFETYILESNEGPARKYYRITSLGKENLSNLMEEWREFVKAVEILISE
                     DEGGNELE"
     gene            73930..75051
                     /locus_tag="KR294_000421"
     CDS             73930..75051
                     /locus_tag="KR294_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactosyldiacylglycerol synthase"
                     /protein_id="HBH0238538.1"
                     /translation="MKDDKTILILTAQFGAGHISAAKAVKECIIEKYSNYNVVIQNFI
                     NASIPMMNKPMVKLYENNTKYTPGLYNYYYYFKKSFDSRHDLSHKLYTPKLSEYIADI
                     NPDLIISTFPLAAACVNNFKIKNPDINIPTLTVITDVVDSMEWVFENTDLYFVPSPEI
                     KNRFFQKGINPDSIKVTGVPVDKRFQIESKELCCDKYRLLLLGGGRGLFDIDEDFMHW
                     IDEFIEEHSNSIEITIVTGKNKKLYDNLTHKKPLKNIKVLGFVNDMYNLIRECDLMLT
                     KPGGATIFEAIQSQTPVLVKMPKVGQEIENAKFIIDKGLGMIYSDDLDLKNIFYKLVS
                     NEFDSIINFMKKNLKEFKTVIHPEKIADYISELIDNHYS"
     gene            complement(75179..77077)
                     /locus_tag="KR294_000422"
     CDS             complement(75179..77077)
                     /locus_tag="KR294_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HBH0238539.1"
                     /translation="MDSLLYVIEKDKHTNEELREILKSNKNIRFVSLMGVDLGGNATD
                     EKIPVELFLEDIDKFLESAIQTDGSSVELYNIATLNNAKVDLMPDKSCHWYVDYNMEY
                     IDEEVGLPVGTLKIPAFLIHDNKKVCSRGVLQKADKYFKKSMYEIFREYPHVINNIGI
                     DSVDDIEEIMLTAATELEFWVNTPEDKADLEKLYVSQSLKEQYWKRTHGIIRTCLEKS
                     LIILQKLGVNPEMAHKEVGGIQSSISIDGRTNHAMEQLEVSWKFSTPLQAADNELLVR
                     DVIEDVFTSHGLEVTFKAKPIHGVAGSGGHTHVGVSAKLKDGSIKNLFAPKDLKEDYL
                     SELGYGALMGLLYNYEVLNPIVTASNDGFNRLVPGFEAPVCIVTSLGHSYEIPSRNRS
                     VLVGLIRDMKNPKTVRFELRSPSPLSNTYLVIAGCYQTMLDGIKAAAKSGLSTKELEK
                     ELSKNVGEESFYLEKDRAYRDENDVFEHYSLEERNARFGIPPATVYENMKNLEIYASK
                     LKSLKQGDVFTDSIIESFKIGAIDKWQKKLKTRIIEAGIQKIRSIVKIHTKENMDALD
                     EVVWNSISDLKFNIMKDTLTRESLFTRVREAIENKDYQTASDLQIELKRSMEEIQQLY
                     MQYKKNIY"
BASE COUNT        26143 a        12628 c         8930 g        29567 t
ORIGIN      
        1 atttactgtt attatgaata tggttgaaat tatttaaata aatactgttg acttagtttc
       61 atatatttac cattaaactt ttatcataaa tatcatatca taataatata tttaataagt
      121 ctaataaact atacgaggtg taaatatgtt aatgaatacc cattttatta tggcaaaatc
      181 aatacttgat aatatagatg aaaataaaac attctttata agcgaaaaaa attttatata
      241 tggcaatata aagcctgatg ctttttctaa atataaatta aaaaaacatt atttagatga
      301 gtcatttaat atgattgttt ctaaaataaa ctatctatgc agtcttaata tagatagtct
      361 ttctaaatac ttttcagtaa gtagacttag tcaggaacta ggagtcatat gtcatttttt
      421 atgtgatttt ttctgtgtag ctcacagtga acgttgggag tttaagcata gcttaaataa
      481 acatgttact tatgaaagag aacttggagc atttgcaaaa gatgttgatt tatctaaaat
      541 taaatgtggt actataaata gtagttttga gaagtttttt actaaacttt atagcgatta
      601 caaaaagaaa actgattata tgaatgattt aaaattttca gcttatactt gtaatagtgt
      661 cataaattat atacttgact ctattttatc taatacaata aaatcatatc atatagcaaa
      721 ttgcggttaa cttaagaatt tttaaactta tataaactta taattgaata taattaaaat
      781 gactgctcta tagaatataa ttttatactt ctctaggaca gtcatttttt atactaacta
      841 tttatctcca ttataacatc tatggcactt tttacactat ctactacata atttgcactt
      901 tgctttacat cttcccttgc cttagacatt gcaaaactat atttaaatcc ttctaacatg
      961 caaatatcat ttggagaatc cccaatagta gcaacttcat ctggacttac atttaacgtt
     1021 tttattacat gctctatact tcctcttttt gacacacttt taggaactat atttaaagta
     1081 tatgttccag aaaaatatat ttctaagact tcactaaact cactttttag ataaagttct
     1141 attctggata actcttccaa attttcagaa catacgccta tatttcctat aagattatca
     1201 aaactacttc ttttttcaaa gtctgggtca actataaagt cactagaata atgtctaaaa
     1261 gcagtggtat cactacccac aattacatca cccttatatt taaaataaag ttgtgcatca
     1321 cttgactcaa atctatcaat gacttttttt actaaattat catctatcgt tcttttaaaa
     1381 attacattat aatctttatc atatataaat gaaccatttt cacatacata gtatccattc
     1441 atatctaaac tatctttgat aatattatgt gcttgtttaa aaattctacc tgtagcaaca
     1501 ttaaactgta ctcccttttt ttctatttct tcaattgcta ctatatcttc ttttgttatg
     1561 gttccatttt catatagagt tccatctaaa tcacaaaata tatgttttat cataaattaa
     1621 aagcctccaa aaacaatttt atattttact aatactttaa tcaaaataac ttaaagcttt
     1681 tctaattgta ttctcaactc attaagcaaa tctctagtag ctcttaatct tatctttctt
     1741 ctatccccat taaatatatt tttctttact attgtttttc catttatata tattgcagta
     1801 taaaccagtc ccacaggctt ctctttggtt cctccaccag gtccagctac tccagttgta
     1861 gatataccta tattagcttt aagtccttta gcaacgccct cagccatttc tatagctgtt
     1921 tgctcactta ctgctccaaa ctcttccaaa gtttctcttt ttactcctaa tcttttcatt
     1981 ttagaatcat tagaatatgt tacacaacct tcaagaaata cagaggatat acctggatag
     2041 tttataagag atgaagaaac caaacctcca gtacaagatt cagccactgc tattgttaga
     2101 tttttttcta caagtagctt agaaacagca tcttctaaag cagtctcccc ttcagatatg
     2161 gaaatatctc cttcagtata tacatattta ccaactctac tttttatttt ttcttctact
     2221 ggttttatta atttaaaagc ttctctttca ttttcagcct ttgcagttat tcttattgta
     2281 acttctaatt cttttgcata taaagcaact gttggattag tctgctcatt aattatatcg
     2341 agaatttcta attctagatt tgactcacct attccatata atcttaaagt cttagatact
     2401 agcatttcat ttgtgaattg ttgtaagtaa ggtttgacac tctcattaaa catagctttc
     2461 atttctcttg gaggtccagg caatactatt ataaatttac catctttttt taaaattgcc
     2521 cctggagctg taccattatt attttttagt actatagcat cttttggaaa gtacacttgt
     2581 ttcatattat tttcggccat ttttttccct gttttaacaa agaaagattc caaaacctct
     2641 agtgaaggtt tatgtagttc taatttctga ccaaagtatt ctgcagcagt ttcttttgtc
     2701 atatcatcac cagttggccc aagaccacct gtagtaatta caaaatcact tctctttaag
     2761 ctttcatcaa aacattctaa aagtctttgt ttgttatctc caacagtact ctgatggtat
     2821 acttctattc ccaatgatgc aagttcttta gctaaaaatt gagaatttgt atttactata
     2881 tctcccaata atatttctgt tcctacactt attatttcag ctttcaaaat ttatcactcc
     2941 ttgatttata gccattaaga ctagtcttaa gttcataaca ataattttag caaaaataat
     3001 aacataaata aagttaaaaa atcatttaaa catatcttta aactagatta ttattctaaa
     3061 accacacata atataaactt cgtatatagt ggtactttca tcctcaactg ttaattcata
     3121 taattaagta tgtaaataaa aagtttactt taaaataata aaaattaaaa taggagtgta
     3181 taatatgaaa atagcagtta taatgggtgg aatatcatca gagagagaag tttctttaaa
     3241 ttcaggaaaa gagatatata ataaccttga taaaaataaa tatgaagttg taaaagtaat
     3301 aatagatgat aaaaaagata tatttacaaa gataccagaa gatatagatt ttgcaatact
     3361 tgctttacat ggaaaatttg gtgaagatgg atgtatacaa tcaatacttg agactatgga
     3421 tataccatac tctggatgtg gacctctttg cagtgggatg tgtatggata aaaatataac
     3481 taaaaaaatg cttagagatt caaacctacc tactgctcca tgggttttag taaaatcagt
     3541 tgatgaaata gactatgatg aaatagataa tataggttat ccagtattta taaaaccaaa
     3601 ctcaggaggt tcaagtgtag ccacattctt tattcattct aaggatgaag ttgaagaagc
     3661 agttagaaaa ggtctggaag ttgatgaatt tgtaatgatt gaaaaatata taccaggtgg
     3721 agaatatact tcattcatat taaatggaga agtgttccct acaatatcta taaaatctga
     3781 ttcaggattc tttgattatg aagctaagta ctcagttgaa aaaggtgcaa aggaagaagt
     3841 tgtttactta gatgaagaac ttcaaaaaag agtaaacgaa atttctgaga cttgttggaa
     3901 aatttttaat tgcaaagcat atgtaagagt tgatatgatt ataagtgaag gtattccata
     3961 tgttcttgaa ctaaatactc ttcctggaat gactcaaact agtttaattc ctagaagtgc
     4021 tgctgctaga ggtattaagt acagtgaact attagataaa cttatagaat actctttaaa
     4081 ttagatgaaa taatttgagg tggtaatttg atattttcaa atctaaaact aaatgataat
     4141 gaaccaattt atatacaact taaaaattat ataagtgata tgatatcaaa aggactaatt
     4201 ccagacaata gtaagctccc ttctacaagg gagcttagtc agcttttaca agttagccga
     4261 aattctgtag ttttaactta tgaagaatta aaatcagaag gattaatcta ctctatttca
     4321 ggaaaaggta catttgttaa atcaaagaat aagtcttcaa atactacatg gtcattaaac
     4381 tgggattgtt tagagaatac atactctaaa aaagccaatg aattggacat tataaaaagt
     4441 gaaattcctt ggagctctga cctgatttcc tttaaaagta tttctccaga tggagattta
     4501 ttcgacatag aagaattaaa aaaatccttt ttaaatagaa tttcactaga aggacataaa
     4561 ttactcaact atggatatgc acaaggttat aagcccctta ttgactattt actagaatat
     4621 atgacaaata agggtgctga tataagtaat aaagatatac taataacaaa tggattcaca
     4681 gaaggctttg atattattat gtcatctttt acccaagaaa aagactacat aatatgtgaa
     4741 aatcctactc ataatactgc tataaaaatt atgaaatctc ataacctcaa tatcttaggt
     4801 gtagatataa atgaagatgg tttggacttc aatatgctag aagacaattt agttaagtat
     4861 aaaaataaaa taaagtttgc atacattaca ccctcttatc acaatcctac aggaattgta
     4921 atgactcctg aaaataggta caaattctat aatcttatga aaaaatacaa tatagcaatt
     4981 atagaagatg gatttaatga agaattactc tacaatagtt ctcatatatt tcctatctgt
     5041 tccctagata atatgaataa tggggtcgta tatattggta gtttttcaaa aattttattt
     5101 cctggaatga gaattggatg gatatttgca gataaaaaag taatcaataa gctagaaagt
     5161 gtaaaaaggt gcagaaacat acatgtatcc tttttggacc aaggaatttt atttgattat
     5221 ttaagtaatg gaggttttga aaaatacatt aaaaaaatac gtaaattcta tggggacaaa
     5281 tttaactttg catataagtg tataaaaaaa tatataaaaa cagaatatat cttgggtgat
     5341 ggtggtttgc atatatttat aaaactaaaa aatatagata ctagagtttt attagaaaaa
     5401 tgttatgaaa aaaatgttat atttatgcct ggagatttat tttttacaga taactctggt
     5461 tttgatactt taagactcgg attttctagg ttgtcttttg aagacattga aattggaata
     5521 aaaataattg gagaaactat aaatgaaatg ttctaggtta actaaatatt gttagcctag
     5581 tttattttta tgaggtataa tatatatagt ttatatgaat ctaatactgg gggataatat
     5641 gagtaaaaag tcaaaacgaa gaaaaattaa taaattaaaa ttaacgattg taataactgt
     5701 attatttctt gctttattat ctatatatga gatactgttc tctaatccca acaaaaaagg
     5761 taatataaag agtcaagaaa ctatgcaaaa taaaaataat acaacagatg attctaaaaa
     5821 taatcaaagc tctaccaaaa agcaggaaga taataatatc aagcctactt tttcatattc
     5881 ttcaatacca gataatataa aaaataaaat gattggtaaa tctatgccta ctgatgaacc
     5941 tataagcttt gatagtctat cttatttaaa acttacatat tatggatttg atgaaaaaac
     6001 tcatcaagga gaaatgatag taaacagtga actagctcca gaagtagtgg atatttttaa
     6061 ggaattatac gaaaaaaaat atccaattga aaaaattaag ttaatagatg actatgatgc
     6121 tgtagatgaa aaatctatgt ctgataataa tacctcatca ttttgttata gaactatagc
     6181 tggtacaaat gtagtttcaa atcatggtaa aggacgtgct atagatataa acccattaca
     6241 gaatcctcaa gtttctggaa atgatgttac acctaaagta agtacagttt atgctgatag
     6301 gtctagcaca aaatttggaa tgataaaaaa aggtgatgat tgttataatg cttttgtaag
     6361 cagaggttgg agttggggtg gctattggaa aaacccagat tatcaacatt ttgaaaaata
     6421 atagattaga aataaaggtg aattatatga atttaatgac attggaaaat ataagtaaaa
     6481 gctattctga aaaaaaatta ctagaaaata tatctcttgg aataaatgaa ggggaaaaaa
     6541 taggacttat tggtgtaaat ggtactggta aatctacctt actcaaaatt attgcaggag
     6601 ttgaagaaag tgagactggt aatataacaa aaactaatgg tattaggata gaatatctac
     6661 ctcaaaatcc aacttacaat gaaaattcaa ctgtacttga acaagtattt aatggaactt
     6721 ctgaagaatt aaagctactt ggtgaatatc aagaaatcct agaaaaactt aattcaaact
     6781 ttacagagga attaaataaa aaattattat cagtacacga aaaaatagat gccttaaatc
     6841 tttgggattt agaaagtgaa gctaagtcag tacttacaaa gcttggtata aatgacttta
     6901 atcaaaaaat agcagaactt tctggtgggc aaagaaagag agtctctctg gcatcagccc
     6961 ttattacacc ttgtgagttt ttgatactag atgagcctac aaaccatcta gacaatgata
     7021 ctatagattg gcttgaggaa tatcttaatt ccagaaaagg ctcattgctt atgataactc
     7081 atgatagata ctttttagac cgtgttacaa atagaattat tgaactggac aaaggtagat
     7141 tattcagtta tgatgggaat tattcaatat ttttggaaaa gaaaatggaa agactttcgc
     7201 tagaagcaag tattgaagat aaaagacaaa atttaataag aacagagctt gcgtgggtaa
     7261 gacgaggagc tcaggctcgt agcactaaac aaaaagctcg tttacaaaga tttgatgaac
     7321 ttataaatag agattctttt aaacctgatg aaaatcttga tatatctgtt gcatcaagta
     7381 gacttggaaa taaaataata gaaatacaca atatatctaa atcatttgaa gaaaatactg
     7441 ttatagataa tttagaatac actttaactc gtacagatag aattggtata ataggcaaaa
     7501 atggtatggg taaatctacc cttataaata tacttaatgg agaaatagag cctgatagtg
     7561 gatatatttc aattggagaa acggttaaaa taggttgttt ttctcaagac gactctcata
     7621 tgaatattga tatgagggct atagactatg taaaagaagc tagtgactat atagaaactt
     7681 cagatggtac taggattaca gcttctcaaa tgtgtgaaag attccttttc aatggtacta
     7741 tgcaatatac tttgataggt aaattatctg gtggtgaaag aagaagacta catcttctta
     7801 aaatccttat gacagctcct aatgtgcttc ttttagatga acctacaaat gatttagata
     7861 ttgaaacgct taaaatatta gaagaatacc tagacgaatt taaaggtgta gtagttacag
     7921 tatcacatga tagatatttc ttagatagaa tttgtaataa aatatttgca tatgaaggta
     7981 atggaaaaat tcatatctat acaggtaatt acagtgatta tcttatttat agagagattc
     8041 aaggaattga atttgaagaa tctaaaaagg aatcagttaa aaaagatgac tctactaccc
     8101 taaaaaaaga aaaacctaaa aatgataaaa agcttaagtt ctcatataat gaacaaaggg
     8161 agtttgaaaa tattgactct gatatagaaa aactcgaatc taaaattgca acacttgatg
     8221 aaagtactgc aaaattttca actgatttta ctaaacttca agaaatttta gatgagaaat
     8281 ctaaactaga aaaagaactt gaatacaaat atgaaagatg ggaatattta aataatctag
     8341 ctgatgaaat agctaataat aagtaatatt aaaataatct taagtttaat aagttttgct
     8401 ttaaatctgt aatttataaa tattttaaag gaagtgtctc aaaatgaact ttttagtttt
     8461 atgagacact cttttttatg agaaatcaaa tatattttca tcatttcaac aatacaaaag
     8521 aggcttatct ctattttgag acagcctctt tcataattac cttctaattt atatgctcta
     8581 atatatctat aataattctt attatatcta tatatccagt ctttcaatat aatgacaatt
     8641 aacttcaata tgatttaaaa atactaacaa cctttcataa agtggatgag attcttctcc
     8701 atatttagct tctaggttct tgcctatttc tctaacagtc ctttgaccat caatttgtaa
     8761 aaaaacaaaa ctggaatatt catctagttc tatttttttg tatttaggta ttctagcttt
     8821 taactttcta aaaaactttt gaattttatg gtcctgtttt tcaagtatag taacaactct
     8881 attttcagct acttcatatt caagtccatc agtaatttta aatacaatat ctaaaacatc
     8941 attactcttg ctcattattt tttactttag ataaaacaat aggtaatgct gtaagcacaa
     9001 ctaaaactac taataaagca attgccattg aatttgttgc agcaaatcca cttggtacct
     9061 ttggagttac aactccagtt acttgtaata ttatacctat taaaccaatg atagaaccac
     9121 cagcaacaag accagaagat aaacttatac cattagaaac tttaacttct ttttcttttt
     9181 cagttttaga tactaattca acaaataaac gaattaatgc tccaactaat attatagaag
     9241 ttgttgcaat tggtaaatag aatcctatag ctatagtcat tattggtaaa tttaatgcat
     9301 atagaactat tgccataaat actccaacaa taatcataac ccaaggtaaa ctacctgaca
     9361 taataccaga agttaatgtt gacattaagt ttgcttgtgg taatgcaaat tgtacattat
     9421 caccagttgc tctaagttgg tcagaaagta ataaaattac tcctacaaca actataacac
     9481 caactatact tgcaattgta aagtaacgtt gcatttcgtt tttgctacca ccaataatat
     9541 aagttacttt ttgagattga gtataacctc cagctatagc aatagcaaca actataaatg
     9601 aaccaaataa aagtaatgat ttattagctt ctaaatcagt ccatcccatt ataacaaaca
     9661 ctaatgttac aataactaga gaagctatag tcataccaga aactggaaga tttgatgttc
     9721 cgattgttcc tgttaaacga ccagctacta tgacaaataa taaagataat aaaagagata
     9781 tgatagctcc aataattgcc ataacaatgt taccagaaat taagaatgct gctaaaaatc
     9841 caataactac tccacctaat aaaagtatca tttgtataga tgaaccttct tctccttctc
     9901 cagcacttga tttagcttta agtgtttctt ttatagaagc gattatagtt ggtataagtt
     9961 ttattgcacc aataatacct ccacaaagca tcataccagc acctatatat tttacataac
    10021 tactagatat tgctccaaca tccatttggt taagaggcat tgcaggatta ttccatacca
    10081 tagctccatc tttagccata tctgtaaagt atcctattaa aggtgctata ccaaagtttg
    10141 ataaaatact tcctgcaaac attgttaaag aaacttcaag ccctactata aatccaattc
    10201 ctaaaagtag aggatttact tcaatatcaa atttccattt gtagaatttg cttcctacaa
    10261 gactcattac attgtttgct acatttaaga atgaaccagt taatacagta ataaatccac
    10321 ttattacaaa tccaattccc atgtacttaa ttgaatctcc accagcctct gaagcaacaa
    10381 gtgtttcaga tatagccatt gattctgggt acataagttt accatgttct tcaactatta
    10441 gatagttgtg aactatagca gcaattccta taccaaataa aactccacca actccaacag
    10501 ctaagccttc aaagaatgta atttggcttc caattaatat aactgctggt aatacgaaaa
    10561 taaatccact tgcaacagat tctccaccac ttgacatacc ttggattaag tttttaccaa
    10621 gaataccctt tgaacgagca aatgctccaa caaaagcaga acctattata gctcctggaa
    10681 tacctgcggc aactgtaaga ccggctttca ttccagagta agttgtagat gcggcaaaaa
    10741 tggcagctaa aataataccg ataatcagta cagctacatt tccaccggtt ctggacttat
    10801 ctgtgatata tggaacgtaa tcttttccac taacctcacc ataagcaccc ttaggtaatt
    10861 ttttgttcat aaaattttca ccccttttca atttgtatat attataacat atatacatat
    10921 aaaacttaac tttttattat tttacaaata gcgagtcaaa actactaaaa tttaacccta
    10981 tattattaat ttctactttt agatattttt atgctaattt tctttttatt tttcaattct
    11041 actaaaaact attaagatat aaaataaaaa aattttttaa tgtaaaatta attttgtaaa
    11101 aaaaatgctt taaaacacgg aaaagtataa aaaatacaat aatcattctt ataaataaat
    11161 tttcaccata gtaaatatat acagaaaatt cttgttttta tgcaaattga ttcttttata
    11221 aaaataagtg tcataaagaa atgtctgaaa tcactttatg acacctatca taataaaaaa
    11281 ttattctggt aatgctcttt tatttacttt tccgattggt gtaactggta tcttatctat
    11341 cctcattatt attgttggaa tcatatatgg aggtagatgc tcatttaaat attctctaat
    11401 agttctttca tttatcttac cactatcttc ctcatcaatt acataatatg cacatatata
    11461 catatctcca tcatcatttg ttctcgatat acaaacaaca cttttaattt ctgtaatatt
    11521 atttattata ttttcaatct catatagctc tatcctaaac tcatcaattt ttacctgatt
    11581 gtccatcctt ccaatataat ctaaatttcc atcatctaac catcttacta aatcaccagt
    11641 tctatacatt aacttattat gttcacaagt tttgtaagga ttctctacaa atacttgctc
    11701 tgttagccct tttttattta aatatcctct tgatatttga atgcctgata gacatagctc
    11761 tcctggtgct ccaattggac atagtttgtt ctttttatct aatacatatg cataagtatt
    11821 aaatataggt tttcctattg gtatttttcc atattctctg tccacatgaa aagaagtcga
    11881 tacaacagta aattcggttg gtccatactc attatatagt tcataattac gctttctata
    11941 tccttttaat ctttctcctc cggtctgtac aactctaagt gaattattat tgcaattttg
    12001 tataaataac cttgcaaatg ctgttggcaa tgctagtata gttatgtcat tttcctcaca
    12061 gtattcattt actgtatatt catcaaattt agcttcttca ggcataatat ctattgatgc
    12121 acctacaagc aaataaggga atagttgttt cattacagca tcaaaactga aacttaagta
    12181 tataccacat atatcatttt ctgtagcgct tatagatttt acgctataat aacacatatt
    12241 tactaaactc ttatgttcta tagctatggt ctttggccta ccagttgacc ctgaagtaga
    12301 tatcgtatat gcacaatttg atgatgttat tttttcagtt aattcatatc caagcttaaa
    12361 catttcttca tcatttatat cgagtactat ggtattctca tttacaacct tacttttgag
    12421 ttcatctgta gttatcacta cttttgcatt actatcttca agaaggtaat tcaatctttc
    12481 ttctggatta cttgtgtcta ttggaaaaaa tgctccccct gatttcataa tccctattgc
    12541 tgtaataatt atgttaatat ctcttggtaa cattacagct actatgtctt cactttccac
    12601 tcctatatga tttaaataac ctgcaagttt atcagttact tcatccaatt ctttatatgt
    12661 taactttcta ttttcatccc tagcagctat attactaggt gttaccttaa cttgctccct
    12721 aaataaatca acataacttt tatcatatgg tatttcatat tgattattat taaagtcttc
    12781 caataatact ttttcttctt ccttacatac aaattctaaa tcttctatta aaatatcatt
    12841 atcttctatt atttgctcta ttatataatc aaattgattt aaaattcttc taatagtttc
    12901 tcttttatat atagatggtt tatactttat ttttatttta agtgccctct tagtatatac
    12961 tattacagat aaatcatatc cttttttttc tatgtcataa tcatatgata aatcaaaact
    13021 tttagctata aatattgtgt ttataagctt agtatttaga tgatttttat tctctatatc
    13081 tgataacaaa tagtatccat actctaaaga cctgctccac tgccttttta gcttccttac
    13141 aacatctata aatttttcac tttgtctaac tcttactctt attggaatta tattcattgt
    13201 tttaccaaaa actacatcat cttcatatat atacttttga agtataaggc catatatagt
    13261 ttctatgata gagtctatgc taatattgtt cactttagaa tattgaatta acctttcatg
    13321 tttctcaata ttcatcttaa aaacctcatc tactacttca tcagaacaat ctttataaaa
    13381 aaaatcattt ggaatttttg ctatattcgt ataatcatct aacaaatcca tccaataatt
    13441 catagctcgt tctaaattaa cttcatacat atcaaaattc ccccttacta ctaagtctat
    13501 agaaaaaatt cttttggaat tttattttca caatatataa atatattaat aatacatatg
    13561 caagctctaa aaacatgagc ttgcataaaa ttacacttat tatgactact aaattcgtaa
    13621 tatttacaat gtttaaaata tattataaca catatatgat tttatttttc tacatttata
    13681 taatatataa attacaaata gttatttaac taatatataa caataccttt tggaatatga
    13741 tatattatat taattaaatt tttataagat aagttatact tataggaggg aaccatataa
    13801 atgaatattt atgctcatag ggggtttagt ggaaagtatc cagaaaatac tattctagct
    13861 tttaaaaaat gtttggatat ggatatatat ggaatagaac ttgatgtcca cagaactaag
    13921 gatggaaaaa ttgtagttat tcatgatgaa aaggttgata gaacttttaa tggacatggt
    13981 tttgtaaaag actttacttt aagaaaatta aaaactctaa actcatcttt tgaaggatat
    14041 caaagcaata aagaatgtaa aattccaact ttagaagaag tattaattct aatttcacct
    14101 acagacctta ttttaaatat agaactaaaa actgacaaaa taaactatcc caatatagaa
    14161 aaagacgttt tagagcttat tttaaagtat aatatgaaaa atagagttct tatatctagt
    14221 ttcaacagca atagtttaaa aaactttcat aaattagacc ctagtataaa aacaggatta
    14281 ttatgttatt tacctataaa caatgtagtc aattttgcta aatttctggg taatagttat
    14341 cttcatccac ctctagtttt agtaaatgaa tctctaattg aactttgtca caaaaatcta
    14401 cttggtgtca atgtatatac tgtaaatgaa gagggtgata tactacactg tctaaaactc
    14461 aatgtagatg gtatttttac taactatcca gatattgctt caaatctttt acactcaaaa
    14521 caatacagct aattatacaa tagtttgtac tccttgactt ttatataatt aatatgtaca
    14581 attttattaa atttatcttg gaggtataac tatggataac ttattaaatg aacttgaagc
    14641 tttaaagagt aatttagata atctaccaat agaaaaaata gaaaattatg atttgagtaa
    14701 aactgcttta tttataattg atgttaataa tggctttgca agacaaggtg cattatactc
    14761 tcctagagta gagtctttaa taaagccaat tgaaatgttt acaaaaaaaa tatcaaacaa
    14821 attaaataga gtaatagcat ttactgattc tcatactcct aaatcaatag aacttttgag
    14881 ttatcctgtt cactgtttgg aaaatgatgt agaaagtgaa ttggttgatg aacttaagtc
    14941 gatagaaaac ctacaaattc ttcctaaaaa ttctactaat ggattttttg cattagaaaa
    15001 tttggatttt gataatatag ataatataat tatagttggc gattgcacag atatatgtat
    15061 atatcaattt gcaataactc taaaatcata ttttaatcaa cataatattg aaaaaaatat
    15121 agttgtacct atgaatttag tagatactta tgatattcct aacgttcacc ctgctgagat
    15181 tttaaactta gtatttttca acagtatgat tcaaaatgga gttaatgtat taaaagagat
    15241 tcgttaagct tctaatactt tacatcccat ataatacaat tatcagatat ttatttttaa
    15301 taaaatttct aatagaaaaa cacagtttta gtgagaagat tacaatttaa aacactatct
    15361 attattacta atcttcacaa tataaaaaat cgcagtttag atattcctta tacaaattta
    15421 taaggaataa taaattgcga tttttatttt taagtagtac aattaattta tactacttca
    15481 gtatttaaat tcatttttta ataatcatac ttattcgtag tttcgcacat tactaccttt
    15541 atttttttat taaacatatt cttatattct aataaaaact catttagttc tgaatccata
    15601 agatttattt ttctatcact acaaagcatt atcttttctt ggtcgattat tacattaata
    15661 tcatttaagt cattttttat aaatgttgtt atacaactct ttggttggat tttttctcca
    15721 tatttctcat aaaatcctgc actcttctta aatgactcta aatcttctgt agatactttg
    15781 ctggaagtat tattactcat aaaacctgct gtagaagggt cgattccaaa gtttctaagt
    15841 tgtttttcta cttcttcagt gtccatacca tatctctcca taaattgctt ttgtattttc
    15901 ataaattttt cttgagatat gttgttatct ctcatataat cgaatatttt tcttgaaaac
    15961 tcagccatag acatctttcc atccataaca gaaaaatata agttatatat gtattgctca
    16021 aatttatcta catcagaatc tttaactttg ttctttagtt cgttaaagtc tattattcta
    16081 tcatcagaca tttttcatcc tcctagctaa atttttactt gtataagatt ataccatatt
    16141 tctattatat ttatatacac actatttttt taatttaacg attttttctg tagcatctaa
    16201 ttcgcacatt ctgcccaaag gaatagttat cattgggata caatgtcctg actgaagatt
    16261 atatatagaa ggtttattga ccttatttgc aaattctatt agtaattcca tcaaatcatt
    16321 ttcttcaata caatccttaa aatctccaaa aattatacca ttacattcct caagttttcc
    16381 tgaagaatat agttgtgtta acattctatc cagtttatat tgaggttctc caatttcctc
    16441 aataaacaaa attttatctt ttgcatctat ttcatatttt gttcccattg tggcaattat
    16501 taaggataaa tttcctccca ttattattcc ctctgcttta ccttcacata cagtataaat
    16561 cttttcttct tttggatttt ctaaatataa ttcatcttta aattctaaag catttaccaa
    16621 tgatttatag gtaaatttac cccatttacc tacatttgct gccattattc catgatatgg
    16681 taaaagacca caatttttat agaaagctaa atttaaacct gttatatcag aaaaacctat
    16741 aaatggtttt ggattttgct ttattatatc ataatttatt ttatccaata ttcttgttgt
    16801 tccataacct cctcttaagc acataattat atctacatct ttatctaaaa acatatcttc
    16861 tatatccctt gctctaatat catcattacc agctaaataa cctttataat ttaaactaca
    16921 actttcagaa aacttaactt cgtaaccata actttctaaa ttaaacttta tttcctccaa
    16981 acttgtattt cttaatggcc cagatggcgc aattattcct aacatttaaa cacctcttct
    17041 tataaaatga tatattcttc tccatactaa atatctctaa tataattata agatatttta
    17101 tttgtacttg atacataata atgatttaca taaaataata taattaatga agaaaaataa
    17161 atttttaata tagttaggat gtgttttatg cttaatataa aaactctttg tcatgagata
    17221 aatgattggg ttataaatat aagaagagat ttacataaga ctccagaact tggattagaa
    17281 gaatttcaaa ctaagaaaaa aattattaaa tacttaaatg aaataggtat aaattatatt
    17341 gaatataaga atcatacagg gataactgca tacattaacg tgagtccaaa ctttgaaaca
    17401 gttgctataa gagctgatat agatgcctta cctataacag aagaacttaa ttattcttat
    17461 aaatctatta atattggcaa aatgcatgca tgtggtcatg atgcacacac tgctatttta
    17521 ctgggtactt gtaatatact atttaaatta aaggattact taaatgtaaa tgtaaaattc
    17581 ttttttcaac ctgctgagga aactattggt ggggctcaac ttatgataga agatggatgt
    17641 cttgaaaaac caaatgtaaa atatatattt ggactccatg taaatcccaa tatcaacaaa
    17701 aatctaattg aattaaaata caacactcta aatgcttcca ccaatacact tcaattaact
    17761 gtacatggtt caaaatgtca tggagcttat ccacatcaag gtattgatgc tattgttata
    17821 tctgctcata ttattacagc tctacagaca atcgttagtc gaaacacaaa tccaactgat
    17881 tctgtggtta tttctctagg aaagattgaa ggtggaatca aagaaaatat agtttgtgac
    17941 aaagtggtta taaggggtac tttgagaacc ttgactcctg aaactagaga gttttcaaaa
    18001 aaacgaatta gagaaatttg cgattttact tgtaaaacat ttggaggaag tatttctgtt
    18061 gaaattgagg aaggttatcc agctcttatc aattcaaacc atctagtaga ttacgtcaaa
    18121 caaaatgctg tagaattgtt tggtgaagaa aatattatcc ttaaagactc gcccactctt
    18181 ggtgctgaag acttttcgta ttttctaaga cactgtgaag gagcttttta ccaccttggt
    18241 tgtgcaaatc gtgaaaaaaa cattacttcc cctttgcata cctctacttt tgatattgac
    18301 gaagattgcc ttattactgg tgtcatgctc catgtaaaaa atgtattatc attctaacta
    18361 ttaatatttt tatttattat tttatattga ccctcacatg atgtcatgtt ataccctaaa
    18421 attacaaatg ataaattaaa tagttggagg taatattatg aaagaaatat taataaatcc
    18481 tataggtaaa atatgtattc aaggcgaaga ggtctttatt aaattagaca aaaagtatgt
    18541 acctgcatta aatgaactcg acgatttcag tcatttaaat gtattttggt gggctgatgg
    18601 gtttgataat cctgaactaa gaagtatttt agaaacccca aaaccttata aaagtggacc
    18661 agacgttata ggaatatttg caacaaggtc acctataaga cccaatccaa tagcattgac
    18721 tgctgtacaa attatcaata tcgaccatga aaatggcata ataaaaatac catatattga
    18781 tgctaatgat aatagtcctg ttattgactt aaagccatat actccaagcg ttgatagggt
    18841 tgaaaatccg tccgttccta aatggtgtag tcactggcct aagagtgtag aaaaatcagg
    18901 agaatttaat tgggaagatg aaattgaatt ttaaattact tttttcttga tttcattaac
    18961 ttgttttcca catttatttt atttacactt accaagattt tatgtcacat atacatataa
    19021 tattaggctg tattatataa tacaacctaa tattatataa taaatttcta tttttccctt
    19081 aaatcattca cattctttct aagctacata agatttttct attatttctt tttgagttta
    19141 atttagcatt atgttgagga aaaaacattt catgcatttt aataaattaa atttttcttt
    19201 tattctgcga ttttataata atcaatttaa cttaaaaata atacctaact attttaacta
    19261 tgttaaacta gtaaatgtaa ccacttatat gttacaattt tatataaaca tcaaatataa
    19321 aaaactatat aaataaatga cacatagtgt tatatttttt tataccaatt tagttatttt
    19381 tcagttacag atttaataat agttaatagt aagacataat atttttatgc cctttattga
    19441 ttatgtattt tctgttatct gttattatca tcaataataa acataagggg gtatatatta
    19501 tgaaattgta tttaagtgct gatatagaag gtacttgtgg tattgtaaat tgggatgaaa
    19561 caaaacttga atgtgaattt tcgcaacact atagaacgca aatgagtaaa gagataacag
    19621 cagcatgtga tggagctact caatctggtg tacatgaaat acttgttaaa gatgcacatg
    19681 acagtggtag aaatattaat ccaaatattt tacctgaaaa cgtcaaaata cttagaggat
    19741 ggaccaaaga cccactagtt atgatggcag gaattgatga aagctttgat gcatgtatat
    19801 tcaccggcta tcactctgga gctacttgta atggtaatcc actttctcat actatggata
    19861 ttgattatga ctattttaaa ataaatgatg aaatagcatc tgaatttact ataaatgctt
    19921 atattgctgc atattataat gttcctgtag catttttaag tggagatgaa atgctttgtg
    19981 agagtgcaaa aaaactaaat ccaaatatag tcactgttcc tgtgtcaaaa ggaattggaa
    20041 atggttcaat ttcaatccat ccaaaccttg cactaaaaaa aattgaaaaa ggtgtcaaaa
    20101 aagctttatc tggagattta tctaggcact taataaaatt gccagataaa tttaagatag
    20161 aaataaaatt tagagaacat tataaagctt ttaaggcctc tttttatcca aatatgaaaa
    20221 aaatagattc tcaaacagta ctatttgaaa cagaggacta ttatgaattt ttaagaatgt
    20281 tattatttat ataaatttca tatcataaat taaggagttg attaagataa gtaataaaag
    20341 aaggattcct ttaggcgaat ttatttctgt atttttattt tttgctgttt tttttggtat
    20401 aactttttgt attttcacgg ttataggaat tggcttctta tcattcttag gatttgaata
    20461 taaatctctt ggagctgtat taattttctt tttaatatat ttttgtataa ccactccaat
    20521 tgattttcta tgcactacta ttttagatat attcagatat gtaaacaaat taccatactc
    20581 aatatataaa ctttgcgaat ttataattga ttttatacta acttttctag ctatgaacat
    20641 aattgatacc tttatggatt cagtaacgat tcctttaagt acagaaatct tattcgcttt
    20701 actttcttat cttttatcag aatgtatgga tttttttgat agggataaga aaaaacctta
    20761 ataaaaaaga tagattcctt aatagaacac atattttcgt atttctatta tttaatctat
    20821 ctttatttta tttaataaat ttttattaat taaaatatag tttcttctat ctccttagtc
    20881 atttgcttag cactatcaaa aaattcttct atatacacta cttcatcact gaccctagaa
    20941 tattctgctg caaatgccat tacatgactt tgtatagctt cttttgctgc tactctaccc
    21001 ttttctagtt ctttatttga aactaattta ataaattcag ctataagatt tctatcatat
    21061 tcctctacca tattctgttg atttgatgga ttcataacta tttcttcgtt ttttccaaat
    21121 tctttaattc ttatctcatt tttatttaaa tccccaccaa cttcaccatg gctaaacatt
    21181 aactttatag ttcttccatt ttctttagta aatgcacata aattaaaagt agccgtcact
    21241 ccattttcaa actgtagtat atttaccata ttgtctacaa cattattatc acatctgtaa
    21301 acacatcttc catatggact tgtcttaagt atattcaata gattctcttc agttggattt
    21361 atgtgaacag ctctatttat acttctatct ttttctaaat aaattctctt tgctgaatat
    21421 ggacattttt tttcaactaa acactgaaga caattttgtg ccatctctcc actagcattt
    21481 tggttattaa gatgctttaa gcttccaaat gcagatattt ttttgcatct acttcctact
    21541 aaatataaca aaatatccat gtcatgacaa ctctttgcta aaattaaagg gctggtttca
    21601 ttgctatttc tccaattccc tctagtaaag ctatgtgcaa aatgccaata tcctatattt
    21661 tcattatatt gtatactaac tagctctcct aattttttgc tttctacaat ttcttttaat
    21721 ttattataaa atggagaata tctcagtaca tggcaaatca taaaaatctt atctttatac
    21781 ttatcacaca agtcatctat atgtaccaga ccatctaaac tattagacat tggcttttct
    21841 aatagtacat gataaccttt ttcaagagct agttttgcta catcataatg tctatcatca
    21901 tttgtagcta ttattactgc atctgccatc ttgtcatgtt taaaaaagtc ttctaaagtt
    21961 tcaaatacat ttttactatc taggttatat ttttgtgtaa atagttctcg tcttcctttt
    22021 ttaggttctg ctacagcaac tatttcacat acatcagaat tttcataaat atatggagca
    22081 tatgcatacg ttcctctatt acctgctcca atcacagcaa ctttcacttt ttccatactt
    22141 taatttatcc cctttatatt atttatacta ctctattata gtctattttt acagacattt
    22201 ggatattttt aataaaagaa acagcagtta taatttttca attttaactg ctgttataag
    22261 ttaatatacc aaacattttt aattaaattt tctttaattt taatacaaag acttaaatat
    22321 taaatacaaa ttataaaaac acttttatct agtttacttc ttcttttctt tgtctaattt
    22381 atctaacttc ttattgtata aaaacatata aaatgctgcc gaaaatacta ttaaatatcc
    22441 aacaacactt aacatatctg gatagacatt gaataagaat atacttaaaa ttgctgaaaa
    22501 gattatatta ctatagtcaa atatagagat ttccttagca ggtgcatatt tatatgctag
    22561 agttattcca aattgaccta gacttgcaaa tactccacct agtaatagat atataagttg
    22621 cataagggtc attggttcat atactgcaaa agcaattggc cctacagtaa ctaatgaaaa
    22681 aactgaaaag aaaaatacaa ttgtatagta atcttctcta tctccaagaa ctcttaaaca
    22741 agtatatgcc attgctgcaa atacagctcc tgcaattcct ccaagatatg gaattacttc
    22801 tacactaaat gttggtttta ttatgaataa agctcctata aatgcaatta taatagctcc
    22861 tatctgcttt acatttattt tttcttttag agcaattgca caaaatatta ctacaaggaa
    22921 gggactcatt ttatttagca tattagcatc tgaaagcatc aacttgtcaa ttgcatagta
    22981 gttaaatata actcctagag ttccaaatat tgacctatat aaaagtactt ttaaattttc
    23041 ttttttacca gttagacttc ctttatgttt tatgataagc caaaaagcta ttatagctga
    23101 taccagattt ctaaagaaca ctttttgaaa acttggtaaa tctccagcta gctttacgaa
    23161 tgcagacatc attgcaaagc caagcgctga tgctattata aacattatac cttttattcg
    23221 atttgatttg attgtgctac tcatacgtac ctcttttcta tataaatgta taaagccata
    23281 ttaattaaaa acttagctta tacattaaat aataattatc taaatattcc aatttatact
    23341 ataattaaaa gtgtaaacta tgtcaagtaa ctaataaatc ttttcaatta ataacaataa
    23401 taattatagc taaaaagtta tatgttttta tggattatta tcagaatata taatataatt
    23461 ttatatagta tagacttttt ttaatttatt atttagattt ttaatagatt ttttaactat
    23521 ggaggtattt aaaatatgga aataaagaga tatgaaggaa ctggaagaat gagtagagct
    23581 gtagttcata acaatacagt ttatttatgt ggacaaactc atgctgaagg aggagtaatt
    23641 gaacaaacaa ctgaagtttt agctaaaata gaagatttat taaacaaata tggttcagat
    23701 aagcaacatt tgctatctgt tactatttat ttaagagata tgaaagactt tgaagctatg
    23761 aactctgttt gggatgcttg ggttgaaaaa ggatttgaac ctgctagagc ttgtgttgaa
    23821 gctagacttg ctagagagca tttgttagtt gaaatgagcg ttgttgcagc tacaaaataa
    23881 tcaatttagc ttataggagg ctatctcaaa acagagagat aagcctcttt ttcattgttg
    23941 aaatgatgaa aatatatttg atttcgtata aaagaaagtg tctcacgaac taaaaaattc
    24001 attttgagac acctcctcac tatttaatct atataaattt acttattctc tattggcaat
    24061 atcaatttag atggatattt acctccatgg taaatcgtat tctttgcttc tatatattca
    24121 atactattat atccctctgt cgtgttgcta ttttggaaaa taaagttttt agcactagac
    24181 gttatatcta gtctaatttt atgaccaact ttaaacgtgt ttgatatttt tgaagttata
    24241 atcgtaaact tataaatctc tccttcttcc ataaactctg acttataaaa actatttcta
    24301 aatctagcac taagtatacc atcagctaat ttaattgaat ttccatctaa atccacgtcc
    24361 ataattttta taacccagtc agtatctttg gcagaacttg atgcaaaaaa ctctaacttt
    24421 atatcacctg ttacagtaaa ttcttcacta aaagcatctg atgtataaca caacatatca
    24481 cttctttttt ctaaatcttt gtagttattt ggaactccaa cttcattctc tgacatatca
    24541 attagttgta ctgatgggtc ttttggatta tatatataac tatcatactt ttcttctaaa
    24601 tcattatcaa atactaatct accatttcct aaagatgtgt tagcatttcc atcacttatt
    24661 agatacatac ttttatctat cttatttatt attggccaat tttcttctgt cttccactta
    24721 ttagaaccta cagagtaata ctctactgga gcagtcgtat ctatgttatt ttctatacct
    24781 tttaagtatt tatcaaacca taatagataa ttataatcca aatcatatct taatgaacta
    24841 tttcctaaag aaataccatt tatatctctt aaagtatttg aattatgcat ccatggacct
    24901 agaatagcct ttctctttcc tttttcatag tcctttataa catctaaggc ctctgtagtt
    24961 cccatactat tatcatcata ccacccagat acaaccaatg caggtacatt tattttatct
    25021 ttttgtaaat gccagtccat caaatcccaa tactcatctt tttctactct ctttaaccat
    25081 tcttccagaa attcaattct atatccaaga gcttcaacag gtatattttc tattggtcgt
    25141 atgtttaaaa catcatccca atcatctctt accattttgc ttctatcaac tttatttctt
    25201 gataccataa atgcccatgc aagcatacca gatacaaaag ctcctccttt tcttggtata
    25261 tcaataaaag ggcttcctga tgttactata ctaactaaag ctttaagatg cttattgcct
    25321 gaagatgcag ctgcccattg gacataacca agatatgatg ctccaagcat tccaactatt
    25381 ccacttgacc attcctgtga tactatccaa tttatggtac tatctccatc ttccctctca
    25441 tgaatcatag gttcccactt accttctgat tcatttcttc ccctaacatc ttgtattaca
    25501 acagcatatc ctctttgtac atatttataa tatatttctt tatcattttc ttttccatat
    25561 ggagttctca taagaattgt cggtgctttt ttggcagaat ctacaaaatc agggagatat
    25621 acatctgtag aaagttttat accatctttc atatcaatca tataatttcc accaaatctt
    25681 atagaatata tctcttcatt tttatgagtt ttttcccatt cttttaatac agtatactct
    25741 tcatatccat ccataattaa tatagtacaa gtttctctag ataaacagat aaaacctact
    25801 attttattat ctacaataat tatatctagt gggaactttt tgtttctttg aacccatata
    25861 tattcattaa gtttagaatg cgtttctcct aagttattta taactgtgtc tttatctgtg
    25921 tttactaagc ttttagtata tacatcaaaa ttattaaata aagactttaa atctattttt
    25981 gtaagattta aataatatgt attttcttct ttgcttattg gttttaaact ttctatttta
    26041 tttgtaaaag gattcaactt ttcaattaat aaatctccat caaagattac atttccactg
    26101 tatagtccag atatgtataa tttaaatttt atcaattaaa ctccccccta taatcctaga
    26161 gacatcttta ttgcatatgc cactgatata cctgcataat ttcctaatac tccaccaatt
    26221 actcccatta cgactgctac acttacaagc gaattccact ttgcagaagc agctactaaa
    26281 gctgaagtag gaccatcagc aattgctcct actatagaaa gtattacata ttgatacttt
    26341 atctttaaaa gtctagttat gcctaaatgg aaaacaaatg aagcaaaaat tatactaaaa
    26401 cagtaaagtg ttatagtaaa agttgaacct aaaaactctt ttatatctac tgaaaaacct
    26461 attgtacata aaaagaataa tgcaacaaat aatcctaaat ctaaatttcc ctttagtttc
    26521 tttactggct ttaattgagc aattataatt gaaattgttg taactaaaag tattcttgct
    26581 gcactactaa aacttgaatt gaaatatcca gcaagtattg ttgaaacttc tgtaacaaca
    26641 aaacctatag ccaacatcca agctatatct ttaatactcc attcttttga ctccataaat
    26701 tcttcatttt gacaatcttc taattctgat tcttctacat gatatggcca aagtttttta
    26761 aacttctttg aattttttaa tattgctggt agagcaaaca taaatatcaa tgttggtact
    26821 ccaattacat agtctgctgc atttgctgct gcaagagttt gtctacttac attaagacct
    26881 gttccaatag ctgtaagatt agcacttcca ccagtatatg tacctacaaa cattccagca
    26941 accttccaac cttctgatat tttttctgca aatactaatc caaataaaaa tgccatgata
    27001 cttacagtta atacagctac aaaaattgca attaaaggtt ctcttgataa ttttgtcatt
    27061 tcttttaagt caacactcat caacattata gtcatagaaa ttggaatagc atatgttgaa
    27121 atagttccat ataactcagt acttactgga actactttta agtttgaaag tattattccc
    27181 attatgatta ttgtaagtgc tggtcctaag cttttaatgg ctttgtatct ttgtaagtaa
    27241 aaacccaatg caatcattga tgtcattaca gcaagtatac tacctggatt tgaaaaaagt
    27301 gtattcatat ttaacctcca aatttatcat aagtttactt ctattcctaa acctggttta
    27361 ttgacaagat tcataatatc tccatccatt acaaatcctc cagatatacc ttctaattct
    27421 tcacaaaaca taaaactatc aaggtcagct tctgttatgt tctttttaga tgctattaaa
    27481 tttgctgctg ctgttatacc aattctcgtt tccagcatac atcctaacat acaatttact
    27541 ccacttgcct cagctatgtt gttgattttt atagcaggat atattccact tgatttcatc
    27601 agcttaatat taaatgtatc aactgcattc ttttttatag ccttaattgc atctattggt
    27661 gaatgtaatg attcatctat cataattttt gtgttacttt tatttcttat gtaagcagta
    27721 ccatctaaat cccaatgtgg aagtgcttgt tcaattgcat caacattaaa ttcttctaac
    27781 tttttgatag tatttatact gctatttacg ttccatcctt gatttgcatc aattctaatt
    27841 cttatactct ctccaacggc ttctctaatt aactttacag cttcaatatc gtcttcagga
    27901 tttatacctg ctttaagctt caatatccta aaaccttctt ttactctttc taaagcttct
    27961 actgccattt tttctggctt atctatactt atagtaatat ccgtttggac tttactatca
    28021 aatcctccaa gaactttata aagaggtgca ttcataattt ttcctttaat atcatataaa
    28081 gctatgtcaa tagctgcttt tgcagaagta ttacctataa taattccatc catgatggta
    28141 tgtatggttt caatatctag tgggtctttg cctattaact cttttttaaa cataagcaat
    28201 actgaaagaa cattatccaa aacttcacct gtaactgctg caagaggtgc tgcttcgcca
    28261 aatccacaat acccttcatc agtttcaatt tttaaaatta tactttctcc atactcaatt
    28321 actccaaatg aaactactac aggttttttt aatttaattc taagcttttc aaatttgata
    28381 tctgttatct tcatattacc ctccttattt tttgaagtta taattcaatt tttaaaattt
    28441 tatactttaa attatattat tacttcaata tatatgtcaa gataatttac tgaaaattta
    28501 ctcttttcca aaatataatg tgataatctt aattcaatta atactcttct attaaatttt
    28561 tttattatta ttttctttgt attaatttaa caataattca ttttcataga cttttatttg
    28621 gatttaatta aattttaatt gtcaaaatct actatgtatt cttattgcca ctacttctat
    28681 gttgtgctat aattactttg ttttaagcga atattttata ttaattttat tatttggagg
    28741 ttcttatgct aggtgaaaag atgagaaata taagaaaaag caagaaaaaa acattaagtg
    28801 atgtttccaa attgacagat ttatctataa gttatatctc tcaaatagaa agagatgcta
    28861 ttgaaccatc cttgtcttca ttgagaaaaa tcgctgaagt tttagacact cctttatata
    28921 tgtttatgga tgacaataat actgatgatt tagtcattag aaaagaagat agagttatga
    28981 tgaaatttcc aaagagtgaa atgttttacg agatagtatc tccaatgcct acaactgagt
    29041 ttacaccttc aattttattt gtagagtttg aacttaaacc agaaagtgag gatgccaaag
    29101 attatatata tcatgcatca gaagaaatta tggtggtaac gagtggtgtg gttgatattt
    29161 gtatgggtga aaaggtagtt agattaaatc caggtgactc aacatttata aaagctaatg
    29221 taccacataa aatcatcaat ccaagtaaag atacaatagc tcgtggatat ggagttatat
    29281 cacctccaat ttggccaata aaatctaaat aaactcaata tgacacacct actttttgta
    29341 gataatataa tagatttaaa tattgctttt attttaaatt taaaatattt actcaaacta
    29401 aaaaaatagc tatttgacta atctaaacca tcttaattat ggtaaatagt aaatagctat
    29461 ttgtaagtta tattataaat tataataaaa attgtatttg ttaaaattaa actgctatat
    29521 catttaatac ttttgccttt acaactctta tatttttcat actcttgtag atatcttgaa
    29581 tcttatcttc ttgctctctc aatagtctat gtgcttcata tatatctaca agttcaaatt
    29641 ttactacatc atttggcttt gcttgtgcta acttatacaa atctacactt ataacgttcc
    29701 ctatcttagt atagccacca ctagtctgtc tatctgataa cattataatc ggttttccat
    29761 gaccaggtac ttgtatagct ccataagaaa taccatcaga tataatatct gctccattaa
    29821 ggtgctttat actctctcca tctagtctac aacccattct atctatttca ttcgtaactt
    29881 tgtatttatt tgataaaaat ttctctactt caccgttaga aaaagcatca aattgaggac
    29941 cttttacaat tcttagtacg atttctgaac tataagttgg aatatatttt gaacttaatt
    30001 ttttatttat tgtaaaatct ttttcctgaa taaaagtatt tatataatct ccttttttaa
    30061 gtgctctacc ttcaaatcca ccaattttag ctcttgtata agttgactta cttcccattg
    30121 caagtggaac atctattcca ccagctattg acacataggc tctagcacct gatttcacac
    30181 ctctaaatga taatacatca cctggattta tttgatatga cctccagttt tgaatttctt
    30241 ttccatttat tttagcccct aaatctcccc cagttactgc tatttgcgta tattcatcaa
    30301 aggtaattgt aggacctaac attaaaactt ctaaagaagc ctcatcttca gaatttccta
    30361 ctaatatatt tcctactcta tgtgcatact catccattgc tccacatcca gatacaccat
    30421 attgaccata gccaactcta cctctgtctt gtattaatgt ttggaaacct cctaattcaa
    30481 ctttgaatcc catatatacc actccctgta ctataacgat atttaaatac ttaagttatt
    30541 tttttcgatt tctataaatt catctaatgt tattggaaca aattttataa aatctccagc
    30601 tctaagcaaa atctgttctt ctctattttc atcatataat tttaaaggtg tcctaccaat
    30661 tatttgccat ccaccaggac tatcaatagg atatacacca gtctgggaac ctgctattcc
    30721 aacactccca ccataaattt tagtccttgg cacttctaat ctaggtgtag ctattctttc
    30781 atccatacca cctagatatg gaaatccagg agtaaaacct agcatatata tcaagtactc
    30841 tctgcttgtg tgtattttta taacttcatc tacagtgaga ttattgtagc ttgcaacgtt
    30901 tttaatatct ataccaaaaa cctcatcata acatactgga atctcatgta ttttaggttt
    30961 tggtaatact atactttcca aattatcttc tatttttttt aaattctcaa tcaaactatc
    31021 aaaatctatt tctaatggat tataacttat cataagtgac ctatatgttg gtaccatttc
    31081 tgttacaata cctttaagat tcgatatttc tattgctctc ataaatgaaa ttactttttt
    31141 gtttatatct tctgatatct catttccaaa ttcagcaacc actgccttat cccctgatat
    31201 caagtatcta gtttccataa atgtcacctc ttctaaatta agcaaataaa gcacctaggc
    31261 tgctaagaga agttattcct gtatatgcag atattaaaac tactattaat ccaaatatta
    31321 aaagccatgt aggatgcttg taatctccaa caatatcttt tcttttagat gctataagca
    31381 taattcctaa tgtgattgga agtatcaatc catttaaagc tcctgctaaa attaataaag
    31441 tagctggttt tcctataaat gccattataa gtgttgatat tgctataaat gctattataa
    31501 aatatttttc atatttatct ataaaaggat ttagtgtctt taagaaagaa actgatgtat
    31561 aagcagctcc tataactgat gtaattgcag cagaccataa tacaagtcca aagaatttat
    31621 atcctattgc tcctgcacta aatttaaaag ctgaagcagc tggattttct gggtcaagtt
    31681 gaagaccttt tgaaaccact gccagtattg ctaaaaataa aagaactctc atcattgtgg
    31741 caactaatat acccaaaaga gaagatttag ttatttcttt tatattttct tctcctgtta
    31801 ttccaccgtc tattaatcta tgtcctccag caaaagttat ataacctcca acacttcctc
    31861 caagtagagt tattattggg aatatcagtc cttttggatt ttctggtttt accattcttg
    31921 atactgcctc tccaacagga ggatgatttg atattgctac atatccaact ataattatca
    31981 ttcctaatgc taaaaattta gttatcttat cgactagaga atttgaattt tttgacataa
    32041 atacaaatat ggctattaat ccacttaata cagttcctaa tgtcatattc atattaaaca
    32101 ttacattcat accaagtgca gctccaccaa catttcctat attaaaagct aatcctccaa
    32161 gagctactaa aaaagctact aaataaccta atcctggtat tattttattt gctatatcct
    32221 gacctctaag tcctgataca ccaattactc tccatacatt tacttgagcc cctataaaaa
    32281 ggattgttgt aattaaaatt acaaatgaaa aattcggtcc aaaatcttgg gtaaattgtg
    32341 cagtctgagt taaaaaccct ggtccaattg ctgatgttgc cattataaat gcagccccta
    32401 taagtgctcc gacatctttt ttatttttag ttttatctgt aatatttttt gtactcatat
    32461 tttatctccc cctcatgtta tcagtcttat actatgttct ctgacgaaca aacttctatg
    32521 ttttctaatg gacaaacttc tatactttct aattcaaaac gctttcttat ttctttgaca
    32581 aactctattg cttttggatt gtccccatgt acacatatag aatctgcttt gatatgtata
    32641 acttcacctg ttaaagtttc tacagttcct tcttttacca tcctaacaac cctatctatt
    32701 gcatgttttg tatcatgtat aactgctcct tctacatttc ttggaaccaa aaaaccatta
    32761 ttatcataag ctctatctgc aaatacttca tttgcaaacc taagtccaat ttctttagca
    32821 gaatttatca tttcactatt atatagcccc aacagtataa tatctttatc gacttcatat
    32881 atagcttcac aaatccccat agctaactct ttatctttag ctgccatatt gtataatgct
    32941 ccatgtggtt ttacatgttg tatattacat ccatttgaac ttgcaaatgc cattaaagca
    33001 cccaattgat attttgtata atctttagct tcctgctttg ttattttcat ctcacgtctt
    33061 ccaaatccta ttaaatctag aaaacctgga tgtgcgccta ttttcactcc atttttttta
    33121 gctagctgta ctgttttttc catatgacta gggtcacctg catgaaaccc acaagctata
    33181 ttagctgatg aaatatattt taaaacttct tcatctaaac caatcttata cgttccaaaa
    33241 ctttctccta aatcactatt taaatctact ttatacaatt tatgacccct ccttgctaac
    33301 attttgatag aataagtagt tttaattttt aaattttgtt tattttatat attgcatgaa
    33361 atattttatc acttgtattc aattttattt ttgcaactat tctattgcat ttaattaata
    33421 taattttacc atttaaggaa tatttttgca attattttaa ttgaacattc atttgtattt
    33481 ctttttcaaa aaatcttttt accatttttt agttaataat taattatttt cacttaaaat
    33541 aagggcttta acctttattt ttaaagtatt tttcattttt aatcacttta tatgcaagac
    33601 agaatcattt ttcttcattc atttgtttct ttcatctata taattatcat tctttgtaag
    33661 taaaatatct ttatattttt ataattaatt ctttatatag ttttaagtat aataaaatca
    33721 tgtatactaa atgcatgtta aaatattatt ttaaaacatg cacaatattt gtacatattg
    33781 tagacatata aacctataaa ttatacaata gtattgttaa gattatatat ttttttaaca
    33841 taaattttgt attgggggaa aaacaatgga taaaaactat acgatgccaa tataccaaaa
    33901 aatagcgttg gatattgcaa ataaaatata cacgggtgaa atacaagagg attcagtact
    33961 atttggacgc tctgttttgg ctggtaaata caatgtatct ccagaaacga taagaagatc
    34021 tgtcaaaatt ttagaggaca ttggcgttgt taaaagcata aagggtaaag gtgttattgt
    34081 actatctcca gacaaagctt cttcttttat aaaaaaatat agagatatta caaatatatc
    34141 atcatataaa tcaacacttt ataatttaat agatactaaa tctaatttag aaaatgaaat
    34201 attagatact ataaataaaa ttttagacta ttctaacaga cttgaaataa tcaatccttt
    34261 agtgcccgtt cagttcacca taaattctaa ttgcaaatat attggtcaaa cagctgcaca
    34321 aactaaattt tggcaaaata caggtgctac aatagttgca attaaaagag gtgaagaact
    34381 tataatatct cctggaccat atattgaatt tttagaagga gacattctct tagtagttgg
    34441 tgaccaacac atttacaatt ctataccaat gtttttatat gaaaacgaaa aataaattat
    34501 ataatttagt atgattatat aaaaatgcaa aattaacaac aaaaaaagag cttcatattt
    34561 tacataaagc tctttttaaa ttcaaataaa tttaactttg attaattttt aaatatccaa
    34621 ttcatcttct ttttcccagc ttaaagctct cgatacagct tttttccatc ctttatataa
    34681 tttacatctc ttctcttcac tcatatttgg attaaactct ttttctactg accactttga
    34741 agtaatttca tttcttccaa tatagaatcc aacagacaac cctgctaaat aagcagctcc
    34801 taaagctgta gtttctacta ttttgggtct atctatatct acatttaata tatctgattg
    34861 aaattgcatt aaaaaattat tattacttgc tccaccatca acttttaatg attttagttt
    34921 taattttgaa tcgttttgca ttgcttctaa aacatccttt gtctgataag caattgattc
    34981 caatgtggct cttactatat gttctttttt tgctcctctt gtaagtccta aaattgaacc
    35041 cctagcatac atatcccaat atggagctcc aagacctgta aatgctggca ctacatatac
    35101 accattagta tcctctaccc tatttgcata catttcacta tcttttgcag attcaattat
    35161 ctttaattca tctctaagcc attgaacaga tgctcctcca ataaatatac ttccttctaa
    35221 tgcatatgtt acttttccat caactcccca agcaattgtt gtaagtaacc catgcttaga
    35281 tttaactatg ttactgcctg tattcataag taagaaacaa cccgttccat aagtattttt
    35341 tgcagtacct tcttcaacac aattttgacc aaataatgct gcttgttggt ctccagcaca
    35401 tcccgcaata ggtattttag ctcctgataa catgcgctca tctgtatgac cataaacata
    35461 gctagaaggt tttactaatg gcaacatgct tattggtatg tccaattctc gtaatatatc
    35521 ctcatcccat tctaaatcat ttatattgta catcattgtt ctagatgcat ttgagtaatc
    35581 tgttacatgt acttttccac gagttaaatt ccatattaac catgtatcta tagttccaaa
    35641 taataactct ccttgttctg ctttttccct agctccttct acattatcta atatccattt
    35701 tacttttgtt gctgaaaagt atgcatctat taaaagacct gttttttctt ttattgattc
    35761 ttccaatcct ttatttttaa gttcatcaca tatttctgac gttctcctac actgccatac
    35821 tattgcgtta taaataggtt taccagtata cctactccaa acaaccgtag tctctctttg
    35881 attagttatc cctattgaag caatttcttc tggtcttata cctgctgttt ctataacttc
    35941 tctcattacc ccactttgtg acccccatat ttccataggg tcatgctcta cccatccagc
    36001 ttttggataa atttgattga actctttttg tgcaattttc actatttcgc cttttttatt
    36061 aaatagtata gctcttgaac tggttgttcc ttggtctaat gccattacat acttcttttc
    36121 catcaccata ttctccttat catataatat ttaatttatt aaaaagaaaa atttaatatc
    36181 acatatttca ataaataatc atacttaagt acaaatttaa tataatagat atttagtaag
    36241 aagacactta ttttctatca tatctatata ataatattat acattatagc ttacatattg
    36301 attaataaat tttaaaggag tataataaac agtgttcata ataattttaa taaaagaggt
    36361 ggtaatatgc caaagatttt agaaaatgta aaagaagata tattaaaagt gtctcgggat
    36421 atgattttag aagaagatta ctcgaatatt agcataagga aaatagctca aaggtgtggt
    36481 ataagtgcag gtacagtgta taattacttt aattcaaaac aagaaataat agaatatatc
    36541 acaaaatctg aatgggattt attgataagg cgaattgaat actccaataa aaacactgaa
    36601 gattacataa aaaaactaaa cattattttt actgaaataa gaaattttat aaacaaagtt
    36661 cataatatcc aatacaatga ctttttaaac acttttgaaa cagagagatt ttttgaaatg
    36721 aaaaaacaca aagacgactt tcatgaacag ctttcaaata aagtatatga agctttagaa
    36781 aaagaaagtt tttttaataa tgacaaatta gtatgcaata tcataataaa aatgtttttt
    36841 tcatattcaa catatcttca tatagaattt gaagatttaa aaccctatat tgaaaaatta
    36901 atacattaag gtggtgttta ccttgaatca taatactagt attaagaaca aggacagtaa
    36961 tccaaaaata tttttagtac ttacacttta tctattaggt atatttatgg gagctattga
    37021 tactggaata gtatcaccag caagaacgat tatacaaaat agccttggag taaatgaaaa
    37081 aacgggaatt tggatgatta ccatatacac attaacatac gcttctgtaa ttcctatctc
    37141 tggaaaatta gcagataaaa taggaagaaa atatgtgtat ctagttagta tatttctatt
    37201 tggtagtggt tcattaatat gtggattatc atcactattt tccaatttct atattttatt
    37261 aattggtcgt gttattcaag caattggtgg tggtggaatc atgccaattg ctacagcaga
    37321 atttggaact accttcccag aaaacaaaag aggcatggct ttaggtttag ttggggcaac
    37381 atatggtatt gccaatattt taggttcaag cattggtagc acaattctaa gtatatttgg
    37441 aactcaaaat tggaagtggc tattttttgt aaatcttcca atttgtttaa tcatacttat
    37501 tggtggagtt ttctgtatta aaaacaataa gtctgaatct aaagaaaaaa tagataagct
    37561 tggtacattg atgttgatat gtataatcgt atcactatta tatggtctta tgaatataga
    37621 cttttttaat tttaaaaatt ctatacaaga tatatcagtt tatccatatt tattgacatt
    37681 tattgtactt atacctattt tcatatttat tgaaaataga gctaaagacc ctattttaag
    37741 ctttgaatat tttttaaatc cgagaatatt gatagtactt attttatctt taattgttgg
    37801 tattggaatg atgggtatgg tattcgttcc acagtatgct gaaaatgcat taaagataaa
    37861 tgctggttct ggtggatatt ttgtagctat attgggatta tttgcaggta ttgctgctcc
    37921 tttaagcgga agacttattg acaagtttgg ggcaaaaaaa atactattac taggattttc
    37981 tgtatctatg ataggctctc tttacctagt tttaattgct ctaaaaacca atactgtatt
    38041 tagtgtatgt gtaagtttaa tatttatggg attaggaatg ggatttacta tgggaactcc
    38101 tctaaactat atgatgttat caaatacaag attagaagaa tctaattcag cacttgcaac
    38161 attatccttg atacgctcaa ttggtacttc aatttctcca gctataatga ttggatttat
    38221 agcacatgca ggattatctg tgcaagataa tattatggac ttagttggaa agccctcaac
    38281 tcctaaaata gttcaacttg aagaacttga aaacatgata gatgacttaa aatcagaccc
    38341 tgaaatggca aaaaatttaa aaaatgtctc tatcccaaat atgaatgata cttcaaatat
    38401 aaatatggac atgacaggtg gcaaacttcc aaaatcctta cttaataaag ttcagtcagc
    38461 agatacaacc aacattacca atataacaaa agaaatatca acaacaatgt ttgatgaaaa
    38521 agttccatct ataattacta aaatacagaa aaatgtacaa aaaggaatag atggaacaca
    38581 aagtggaata aacggtattg aagatggtga aaataaacta aatagtggta ttaaaggagt
    38641 tcaaactggt attgacaata tggtaaaagc tagagctggt attaatcaag gaatagatgg
    38701 tgtaaaaaaa ggtattgctg gtgttgacaa aggtataaaa ggtatggaac aaggtcttga
    38761 aaaacaagat gaggccatca aggaacttac aactgcttat aataaaatac ctactacaga
    38821 aaaaactcct actgataacg aaaataactc aaacgaacaa aaccagagta ataccagtaa
    38881 ttctgaatca gatgacacta agaatgattc tacagaaaat aagaataaca attccagcga
    38941 gaataaacca aatgtaaatg aacaaaaaga aagtttaaat gctcaaatac agcaactaaa
    39001 aaagacaaga gatgacttaa atacaaagtt acaaaaaaat aaaactcaaa agaacgaatt
    39061 aagtaaaaaa ctaagatcaa tggaatctca aaagaaagag ctacaaagca agttaaataa
    39121 ttctataagc caaaagaaag acatggaaaa aagccttgat acaatgcaac agcaaaaaaa
    39181 atcactccaa gcagttttag caaagacaca agaggtaaaa actgaaatac caaaggcttt
    39241 tgataaatca aaattggatt atataaattc catagaaaat aatagaacaa aaatagaaaa
    39301 cacactacaa tctactctaa actcaggatt taaacagatg tatataacag tattctgtgt
    39361 aaatctacta gcatttataa tattattgtt ctataaagaa aataaaacta gataaaagag
    39421 tgttatagta ttatattgta aatttatctt attcttaaat attttattct aaagaataaa
    39481 ttcataaaat ttttgtaatt gattaatata aattacaata taatactatt tttctcttaa
    39541 tctttttctc ttttacagac aatcaaaaag caatcttagt ttatcgaaat aaatttatac
    39601 aatctattca tacacccctt tacatttata taacaattaa acctattgtt atatatacaa
    39661 atcaaaataa accatatatt ttcaactata atatgttaaa atcatattat gagcatatta
    39721 atttaagcaa aatgtcattt agactttaat ttagtagttt tatattataa atttatatat
    39781 ttttaatttt aaatgtcatt tagacattac tcataaaaag aaaggagtgt attttgtgga
    39841 tactttagga aaaagaattg cttatttgag aaactccaaa aaacttactc agcgcaaact
    39901 tatggatatt ttaaaatttg aaaacttagg caagtatgaa acaggagata gaaaacctaa
    39961 ttgtgatata ctaatgtcaa tagctgatta ttttaatgtt acgactgact ggcttctcta
    40021 tggtaaagag aaggtaaatg tcaatagtag tgtaaaagaa gataaagaag attacttaca
    40081 tgttactaat gatgaaatga cgatattaaa tctatacaga caactaaacg aacgtgataa
    40141 aataaaaata gaaggaatac ttgaacttaa gatatctgaa tataaagact taaaaaagca
    40201 ttcctctaat aataatgaag ataaaatggt ttaaacatac ataatttgat acgattttac
    40261 atcatctatt aaccttcttt ttttgtagta tattactaaa atatggatat tggattattt
    40321 aaaaacaagt atagtctaat ttcaagcaca tttataatat ttagattatc ttatccatat
    40381 tttagtttaa gtactttgaa aaatataata catctctatg tataacttat attcctaaga
    40441 aatgcattac tcatgttttt aattcttcca acatctttct atacacaatt gtacatcctt
    40501 cataattccc ctctttaaga aggattgaac atgtactaga atatttagtt aaagtattta
    40561 atctttccat atttaagctt tttatattac tgagtgctgt aataaaatca tcaattgctc
    40621 tacaacactc tataacccca tctgaatcca atttacacac aagaatattc acctacttta
    40681 tatactattt attaatcatc ttctgaatat tctatattaa gtaattgata aattgatgat
    40741 ttatattttt tacctgttct tcttccattt aaaatagctg acaaatagtt ttcattaaca
    40801 cctattttct tcgctaattc cctttgagtc atatttaatt caataagtct ttgcttgact
    40861 tgcactccca aaaaaggtat ccattttttt cgagcatcca tttatcaact tcctttctaa
    40921 gcgatttata tttactttta tattatttta gcttacgcac cccctctatt tagtatatat
    40981 ttttaatatg tacacatatt aagtatataa atttatttaa tactaaataa gattttttga
    41041 ttactttgtg ctaaaattag gatgtaaatt cgtatcatta agttaattat aaagtcattt
    41101 tgaccttaag tcaatggttt ttatgtcatt ttgaccttta atttgaaact atttacatct
    41161 taaaaagtct ttttgacatt aattgaatgg agagtgttta tggatacttt aggagaaaga
    41221 attgtttatt tgagaaaagc aaaaaacctt aaacaatatg aactagaaga aatgttgggc
    41281 tgtgacaact taagtaaatt tgagagaaac attagaaaac caaattatga aatattaaaa
    41341 tctatagctg agatatttaa tgtttcagta gactggctat taaatggaga taatctatca
    41401 cataaatcag atttaatttg cgattcctcc tcaaactatc cacttaatag cataaactct
    41461 aatgaaataa agcttttaaa caattttaga aaattaaatg attatgataa agctaaaata
    41521 gaaggtatga ttgaattaaa acttcatgaa tatgaaaaag agaaggattt aggaaaaatt
    41581 gagtataaca aaaataaaga tgagaaaata gataaataat ttttatgttg cttttgatac
    41641 gattttacat catttctttg ttctaatatt tttatttcat ttattttctt ttttataatt
    41701 ttatgataaa ataattagta tattttgctt tacttgaatg taattattta tacaaaagtc
    41761 aaacataata taaatgtagt aaatttttag tttcaagtaa tatctcgtta ttataactaa
    41821 atatttatta aaattaggag gataaaatgg gcttaagaga caaattcgcg caatcatttg
    41881 ctagatcaaa aactatgagt ggccctgaga aaaaggctaa tgaaataatg ggtaaattgc
    41941 ttcttaagaa agctatatta cctatcgttt taatgttcgt gataataatc gctggagcta
    42001 tgcttaaaat caattcttgg gttacacttg gcataaattt agttattgct gttggtgctt
    42061 tcttctacat aagaaattct agtaaaaagt atcagaactt taaaccttat gttggcaatt
    42121 tgattagttt agagaaaaaa ggtaaaaaag agtacgttgc tattataaaa caaggtaagt
    42181 taccagttaa gttacaaata gcttatggtg gtgaagacct tgaacatgtt aagaaaaatc
    42241 aaatggttca aataagttat aatccagatg ctaaaatagc tattttggtt aatagacaat
    42301 aatttaataa aaaaaaggag ttgtcttaaa attgattttt tctaatcaaa tttaagctca
    42361 actccttttt taatttttat atgttatttt tattactttt tttaattaat attttaaata
    42421 ttaaatcctt ctcaataaaa tagtgaacta tctacaatac tactttatct tttcctaaca
    42481 atatataatc tggtgctact ctttcatgtt atacaccatt ttgtaacata ccttttatat
    42541 cagtaacatc ttccttaatt tcctctacat ctgttttcat tatacccatt tgaacaagta
    42601 tatttttgtt tatttcttgt tgttgtgtag ataattctat aaaattttct acagtttttt
    42661 tatacatgtc tctatcttct tttttctcct gcatagtatt tttaaataat agagcacata
    42721 gtatacctat tgcccctaga ctactcaatt cggttattaa tttatccatt atagcctcct
    42781 attgtctaaa ttttttatac ttatagcttt aatttttgtt gtattcttac atcatgcaat
    42841 attatatttt caggattatc aatttaatct tctgtacttt aaattgtagg tgtaatttat
    42901 agattgaata aataataaat atatatacaa gttctaatgt aacaaaaaat aagtacaagg
    42961 cttacttatt aaagttaaga ccttgtactt tacataaaaa aaataactaa tacatagtta
    43021 ttctaaattt actattcaac tggtatttct aattctttac atctaattct aacttgctct
    43081 ctaattactg ctggtacttc ttctattgtt tttttgcctc ttaaaattaa agctacatat
    43141 acttctacca ttccactctc acctccagat tttcttacac taaaagtgct tatattactt
    43201 gcttcattga cagaactttg atttaacaac atctcatata tttctacatt tgctataaaa
    43261 ttatttgtta tatcatcatc ttgctttact tgacctatac ttatgtctga aatgtcttta
    43321 tactgcattt ctacttttct accttgtttg atttgttcta ttttattttt atcgaattta
    43381 aacaattttc acacctccat tttaagcttg tggctcgttg ttttcagcat catatctaaa
    43441 aatcatagat ggacgtttta tagctgtcca tttatctcct ttttctacta tgattttagg
    43501 ctgagcactt tttatgttgg cttcttctaa ttcatagatt tcttggtaac ttgagtctga
    43561 ttttttgatt tcaactagtt tcatgtcttt gaataagtca gatttattta tttttacttg
    43621 aactttagtt ttatttatta attgatatat aggattgttt tccatcatat catcctttaa
    43681 tccctcattt aatgttacta ttaagtcagt gttattttca gtaatgttta tgattgaata
    43741 tactttattg tttatcatta aaatagaatc cttttttact ttaagccctg tttctgattt
    43801 aaatataaac atacttgaat ataaatcgcc tgtaggacta ctggctttaa tcagtatctt
    43861 attttctcct aatactattt tattttgtgg tatctcaaat ataatgctat ttatttccaa
    43921 attagtctta gtagatatta attcatcatt tataaacatt tcaagttttt ctataacatt
    43981 attagggtct tgtactacaa ctctcacttg agatattgat ttttcaacta tttctataga
    44041 tgctttactt gtatctactt ttgttatcat gtatattgta tcatctgaaa gctctatatc
    44101 taaaatatca tttagatgtt caggaattgg tattttagta aattcatata aatcagtaat
    44161 tgatatagat attttataca tagatttatt tttaccagtt atccatagac tattatcatt
    44221 tttaattact agtatgtggt catcattatg tgacttaatt tctttaacat tagttaatac
    44281 tttagtaaaa gttcttatta tcttatcttt ttcactttct cctagtccaa ataatccatt
    44341 tgtattgtac ccttgagcgt acaactctcc ctcattagtt aaaacaagtg tcattgagtt
    44401 atatatactt atatctttaa cagaaggtaa tccagtaacc ttttgtaact ctcttacatc
    44461 attattgtgg ccaactccca attggtactc agtattcttt ccatatgacc atagagtatt
    44521 atctgtctta ataatatagg agtagttatc tccacaagca acttttttga catctgatat
    44581 atttacttca gtaagagtta ataattctat atcttcaagg gtttgattaa tttctttata
    44641 tgaattactt cctattccat ataacttgcc atccttagca acagccaatg aatgtgtttt
    44701 tgatatatca atatcagata cctcaaatgg caatattatt gaagtatact taaaattatc
    44761 tttaaatatg tttttataat ttatatactt attatttgtt tttatatact tatcattaaa
    44821 cattactagc ttttcatttt tcttattaaa aactatttta tctgatgtgt tatctgtttt
    44881 aaaatatgaa tgtagggaac cttcaagagc ttcattttta tcattatcat atctatggtg
    44941 aatacctaaa tgattatatc tattatctcc tgttgaagaa taaaattttc catatatatc
    45001 tttaataaat atagtattgt aactagaaaa tacagtatca acatctttct ttatagatac
    45061 tttataatat ggaactgaca tatccctata agattcatca gatataccat aagtatctct
    45121 acctgatgat atcaaattgt tattattatc tatataaagt gtattattag ctgttacaaa
    45181 aacatcttta acatcttcca cactatttgt attattatta tttgctatac ttccatatcc
    45241 actaagacct ccaacaaata gtttattgtc atttgttaaa atggctgaag tatatccatt
    45301 aactactatt ttttttgcat ttataatatt attaattact cgtatcccct ttatatcatt
    45361 agtctctgtt gaaaagaata ccctctcttt tttccctgta gtataaatca tattgtcatt
    45421 tgttataaaa aatgtagctt cacttcctgc tgtcacaaca gattttacat tctcaatatt
    45481 tatttttgta aatgtactta tacttccttc agtaaaccca aaatagccat ttacaagtcc
    45541 acatacatag catgtattat catttttaac aatgattgat acatcattac atagatatac
    45601 atctctaaca ccatttatag gtatacgtgt aaatatattc ctacttgtag tatcacccaa
    45661 tcctaactgt ccttttccat tattacctgc tccatataaa agaccatcat tagttaataa
    45721 tagagatgtg tttccatata cagctacata ttttacattt tcaacattta ttttagtaaa
    45781 tatatttcta tttacattat ctcctattcc taactgacca gaattattta aaccaacagc
    45841 ataacaggta ttatcatttt ttatcgcaaa tgcatgttta ctattgtcag taaatctatt
    45901 tacatttata gattttatat tatcaatatt tattttagta aatacctttc tatttatctc
    45961 atctcccact cctaattgac ctacatcatt taaaccaaca ctgtaaagca tattattatt
    46021 agttaataaa tatgtagact ttgaatggct atatatttct tgtatattag aagatatttc
    46081 actactgcta ttctttttat tgtaatttat cttattattt aaatttaaac tactattaac
    46141 tgatatacca tgcgtaccct tagagttata tccacatata aataagctct tatcagttaa
    46201 tattgcaaat ctagttttat ctctacttaa atcataagga ggtataaata tattttttat
    46261 atttttcatt acctttttat aattagtggc attatatcca tcttgtgtat ctgaaacatc
    46321 tagttctttt gcactttcag atatattccc aaaaccatat agcgtgttag aagataaata
    46381 caatagagct ttatataaaa atatggcttt atcagaggta ataggacctg aatttatatt
    46441 agatgctgca atattattag atgattgatt gttaagataa ttccttccat attgatgtat
    46501 ataagatgaa cctccagaaa taagtaaatt atctggattg acatttttta aattacttga
    46561 cgattcccca ttatataaat aagcaaaagt tgtagaagat gatgattgtg tacatcttgt
    46621 aggataataa ttatatatat aagaatcaag atatcctgca tatgaaattc cctgatattg
    46681 aactctatag cttgaatcag ttggttttgt ccatgaagta ccatggtatc cagttagaaa
    46741 agatccaatg tttgtacaaa atacagttac atactcatat atgataatat tattaatttt
    46801 agtaatatta ttcgtgcatg aaactctact ataacttgac cctgatatat ttatataata
    46861 ccaatcactt aataaaccta gatttacatt agatccatca gaagtactaa aacctaacag
    46921 gtaatttgta tttataccag ttgcatatac ctttttttca tcaactacaa taaatgttgc
    46981 attatatgaa ctataagcat cagttacatt actaaggcta atctcagtat attgacttat
    47041 taatgcatta ctaagtccat taacataact tgaactcttt ccagaagtgt atatttgctt
    47101 attattagtt acaattaatg aaaaccagtt tgataaatca gtatttataa caactttttt
    47161 tacattatct atagatattt tcttaaatac atctgaatta gaaggaagaa cacctgctat
    47221 tgagttacta tttggtccag aataataaca agtatcatca tttttaatgt agaatattcc
    47281 tccagaaata ttttttgatg ctactataga ctttacatta gagatactta attttgtcaa
    47341 ctcatttaat tgacttggta agtcagaacc cattcctttg tatctattat ttcctagacc
    47401 atatacatct ccattcccta aaataaccag agtacaataa ggactaaaaa cgacatctct
    47461 tacagaatgt atatctagtg gaagttcaat atcctttatt tccatttctt cttttaataa
    47521 agttaattta tcctcagatt taattaaatt tatataatta ctataactat atttttcact
    47581 atccattttc ttaaattcta caatgtgcat atcatcaaaa aacgaaccta attgtccata
    47641 agtattatct cctgtacaat atgaatcatt atttgaatca attagtatgc tatgtgataa
    47701 accaatgaaa atattcttag ctacaatatt ttttaaatct ataaatgaat tatctatatt
    47761 ctcagagtaa tttgctatac ctaactgata tatatcatta tttccagcaa cctttaaagt
    47821 acctttgtta tctataagca tagtgttacc atgaccacat gcaatagttt ttatatttac
    47881 ttcttctatc ttagtaaata gtgatgattg aagtgcattt ccaaaacatt tttcctttcc
    47941 acaaccatat atatcattat tatacgtcat taacacagtg tgttcagaac cacaagctat
    48001 agtcttaaca tcattaatag aaactaaact aaataaatct ctattattct tatctcctaa
    48061 acctagttga ccttgattat taaaaccagt agaatagcat ttattgtcat tctttattat
    48121 aaaagctgat ttattatatg aaaatacagc ctttacattg tcaacatcta cttttgtaaa
    48181 tgtatttaca tttgcagatg ctccattagt tcctagacct aattgaccat acaaattatt
    48241 tccagcaaca tataaagttc catcattgta taaaagatat gttgattgaa gtccacatgc
    48301 aatatccttt acgcctttta tttctggaac cttctcaaat gtagaaactg ttttccctac
    48361 tttttctaat cccaatccca tttgaccatc tgtatttata cctgcgacaa gtaattctcc
    48421 atctgaagta agtataactg catgagattc tccacatgca acttttttaa tattggtaga
    48481 tatatttggt attttcgtaa ataattttct tgttgtattg tcttctccca atccaagttg
    48541 aaagttacta ttatctccac atccatacaa gatattatta ttttttagac caaatgtata
    48601 gttacaacat ccagtaaaaa aattaataaa gtcataatta tcataccctt catcaaattc
    48661 atcaactacc atatttttat cgccaaagaa attacctctt tgaagtagtt tagttctttt
    48721 cattataaaa acctcctaat tatcttattt catacgaata tttatttaaa gttatatctg
    48781 tctgaccaat tgaatatgcc ctattagatt ttgtttcaac aaagttatta tccatttcat
    48841 gtatatatct aactctattt gcattaaatg gtagcaccac attcttaaat gtaacactac
    48901 caagttctcc agttatacac tttctattta aatctaactt aaggccttct atagctatta
    48961 tgtttttagc attagttaag gtatcatacc aatatccagc ttcatctaca tctatttctg
    49021 actctaattc taagtatatt aagatatcta atactttttc agataattta ttgtaactat
    49081 tttttaatac agatagttca gtttgtattt gacctcctat tacatcatca atagatatat
    49141 ttttaatttt ttctactacc tcatttatag ctcctgataa gtttttagct tctgtagata
    49201 agagttcttc gccaattttt acttttattt cttttatatt tttatcaaac ttatcatcta
    49261 aatcttgaat atccttttga gttacaaaaa ccaacgtcgg gtctacttct aatgtaacat
    49321 ttgaagtatt ggacaattgt aaaatcattt ttacaaccaa atctttaata ctgccatctt
    49381 cagcacgtgg cttatacgtc tctggatact tacctatagc tattatatta ttctcattat
    49441 ccagaacagc agcttctctt atcataaatc caccaactgt tcctggtaaa atagtctcta
    49501 taactatcca attaggattt ttttcatcaa ttcttagaga atttatattt ccttcccaaa
    49561 ctacattctt taaagcagtt tgttcctctg ttggctcata atattctcca ttactatctc
    49621 caacttgaaa cttggttaat ccaacaagct ctcctagtgc agttgcattt gctatttttt
    49681 ctctaccaat tttggttaat attatataaa atttttcttc caattatacc acctccgatt
    49741 taggataaac tactacattt tctacacctg tatcatttgc aatagctata ttaatcttac
    49801 aattattttc aatgcattta atgcttaaag gataaacctt tatttcttct ctacttatca
    49861 ttccagctcc acagtttaca acagcactac attttataat tggttcaaag tatggatgaa
    49921 cttttacctc ttcactacat accatacctc caccacaata gaccatactt ttatctagta
    49981 ttattggttc taaatagtgt aataagtgag caggttttac tctttcaatc atatcgctac
    50041 aatctaaaag agttttatag tcacagttat ttgctataaa actcaatacg aatgtaaatt
    50101 catcactata aacttttata tctgtttctg attttgtata tgcctcacat atacttttta
    50161 taacttcaat agtactagta cctctgcttc tcattttagc ttttatattg ctacgtcttg
    50221 tgtcaaaatc aagttctttt ttttcaatgc agagtatgtc ttcccacata tctaatcccc
    50281 atgttgcagt gtcaacaaat aattggttaa aggtatcatc aatatcttct ttaagaatat
    50341 ttaattctgt atcgtatgca ccttgtatct cctctacaat gtaatttcta tcaaatgatg
    50401 gtagtttatc aattagcttc attgattttc cacctcacta aaattaacag ttgttacact
    50461 aggtatttta tcttcattaa tagttatatt atctgtactt ccatttataa gtaggttact
    50521 taaatcgtgt acaccagtag tatttataag tattcccatt acttttgtat agattatctc
    50581 tcctctaata tctctaaagt atgtatttat actttctagg aaagattctt ttacattgtc
    50641 taatgtatat ccatcttcta gtttcattac tgcacttata cttatttcta ttggtaatgg
    50701 tgtcacaact gttatagttg gtccaatagg cttctcttca tctatatgtt gctgacacct
    50761 ttcaattgtt tctgtatcaa cagcttgatt atttttccca aatatcaaga ccttaactgt
    50821 tcccggacca tcccatcttg gataaacctt aacattatag actccatcta cttccaaagc
    50881 ccattcttca tagtgagctt tatttccact tgtagcttga tttctttgga ttttataaaa
    50941 tctttctttt agttcttcat ctgtctctat atctgtacca ccttcaaaac ttcttgtgtt
    51001 agtaatcttt gttactccag atatattatc aactagttta aattcacaat ttgtaggtaa
    51061 attatatttc ttaccaactt ccagagcttg aactgggcta ttgtcacctt cttcactacc
    51121 aatagttaca tcttttatta ctacaaatag taaatctcta tatgatatta ttgtgccatt
    51181 atttattaca gtacctttct ctccaataaa ttcaacttct ccatttgact ctgtacctaa
    51241 ctttctatat acaccaaatt cattgactct tttatcaaga aactggttat atgtgtcttg
    51301 tataaaagcc attttatgca tctttgaaag ttctagatat atcttcgaaa gttctagatt
    51361 atttccagat accatgttgt ttagaaaaga accttctcct ttataaatat caagattaat
    51421 attttcaaga gttctatttt ttattacttc atatgtctgg tcactataca tttatttcca
    51481 cctccccata gatagtggat acttttacat ttgcactcaa tatgtctctg ttaaagttag
    51541 cactttttac gtttacttct aatatatatg gatttattag aagggcctct tttatgaatc
    51601 tactagcttc actttctgta agaccttttg tatatttttg tcctattagt tctgaaagct
    51661 ctgtcccata ttctaaagag tatatctcat gttcatatct atttgtcttt atacacttgt
    51721 atatccaaac ttttaaggct tctttttttt caattatttt aaagtcacct ttttctaaaa
    51781 taggttcatc tttttcaaaa tcccatgcca cttcacgaaa gattggcaat tcttctgttt
    51841 taggtaagat ataatcctct gggacaccta taaaaggaaa tattgtactc attataagct
    51901 caccaactta cttacaacag caaatttttc gcctattcta aacattatta ccatatcccc
    51961 agattcaaag ttatctataa aaggattttt tacttcatgc tggtgttctt gatttgtttc
    52021 tgtgtcaaat gtttctagct gtctatcaat catccaacta tctatcaaaa tatcttcttt
    52081 ttctaatatg atgttatttg tctctatttt taaatctggt aatttacttt taatttttcc
    52141 aataaaaaaa gaaggttgat tatgatactt tccttcttct cttattattc ctataaattc
    52201 atttattgga ttagccatta tatcaccatc cttttataat actctcctag ctgtgttaaa
    52261 atctcttcta ctacttaact tacttatttt aactacatca cctttttgtg gagcatgtaa
    52321 aaattctcca ttacctatat ataatccaac atggctgact ggattatgaa aaaatactaa
    52381 atctcctgct tgaagatttt tttgttctac tttcttgcct tttttagatt gttgatttga
    52441 cgttcttggc aaactaacat taactttttt aaaacaatag accattaaac cagaacagtc
    52501 aaaactactt ggtccatttc caccccattt ataaggttta cctagatgtt tttttgcttc
    52561 tgatattact attttagctt tatcagatac attaccagaa taaccaccaa taataatttt
    52621 tccttttctt cttccaaatt tactagcttc ttcaacattt ccaaataaaa tatctatatg
    52681 gtatgttcca ttcttttcta tagttattgc aggtcctacg tcatttactt tatagactcc
    52741 atcacgacca gaaactcctg taattacctg tatttcatct ccatagttta ataaaggatg
    52801 tttatttaaa aactcttttg tataataagt ttgctcatat ttaccaacca taggagcagc
    52861 gcaagttttt ttagatgggt caagtttttt ctttctacaa tctgtatctc caccttcttc
    52921 ttttctagga cagtaagctg taaattctgc tgtaaactct tttcctcctg cataatcttc
    52981 tccccctaaa ttactttctt ccttaggttc atcctgtcct gctgactttt catccataag
    53041 attttgaaaa ttaagttcaa gctcaatttg atattctcca ttttgccaag tatgtttgtc
    53101 tgtatctata taaaatagtc ctacaagctt tgtataagaa tctttaactt ttactcctct
    53161 accagttata caacttacat ctccataacc tttaagagaa cagctttttt ctatcccatt
    53221 aaactcgcta tcaatatcta catcttgatt ttcttgttgc tgaattactt tttgcattat
    53281 tacatttact tccttaaaaa tttcattatc tattttttcg ctaatcttgc ttccatactg
    53341 gtctaccact attactttat tttttacatt ttccatgctc tccgaaaagg tggtatttat
    53401 aatattaaat ccctcttcaa acataacact taatgtaaca gttccttttt caataacatt
    53461 aaacttatct aaattggcct ctatcatata ctttttcttt gtctttttac ttgcttctgt
    53521 atatgcactc attattgtgt cataaccatt tactcctata aacatctttg tatacttgac
    53581 attggtcttt gctattattc caactgaaag cctattttca gcaaatactt gctttgctat
    53641 gtcttcaact aacttatctt taaaattgta tgacacttca ctttgtgtaa gtaaaaatcc
    53701 catatcttta gatacaaaac taatttcatt actgcttgaa tctttagacc tattaattat
    53761 cattcctcta aagagttctt tctcatctac atagaaacag actgtactag ctattggtat
    53821 atcgatttgt tggaaattta catcaaatga tgattgtatt attgaaaact ctagtgtcct
    53881 tgatggagat ttataatcac ctgaccatga taccttgtct actatgtcag ttatgtcata
    53941 tatacttccg ttttttatgt gtacccaaat cttaataata aaaaatcacc tgccttttca
    54001 tttaattcta tcagcagtta tttataactt attatctata atagttattg ttttggagtt
    54061 acttttggta tctttattct tttatactct tttaaatcta atgtaaaata tacatctcga
    54121 gtcccatctc tttcttcata actaaaccct tcaattatga cttccatatt tatatttgtt
    54181 tccgtaattg taaatcttaa tataaaacct tccttcatcc atttttctat cttatttaca
    54241 caatcatatg gtgatggaaa acctgtatag tcacagaaag tatagtcttt atttggaaaa
    54301 aaacttgata ttgaaatgct tttaagagct acaccaccaa aagttgctat ttcacctatt
    54361 ttgagtatac tagaagagtt tacagcagct tttccattaa tactaaagga agatggaaat
    54421 actggaaatc taaatctatc ttcagcttgt ctaagccaca tttccattat aagacacccc
    54481 ctaactgtgc caattggata cttgcaacta attttgatgt tatcttttct atatcagctt
    54541 cttctctaat cactattgta tcagctaact tagctatgtt tatatttcca ccattttttc
    54601 tgcttctata ttgatttgct tcttgtttag ttaaaaccat ttcaccttca tggagtctgg
    54661 tttgatagtc attataagga acatagttca atccaaatgc attattacct ttcttacctg
    54721 aataagcttt accagaatca ccagcctttg ttccagcata tggattatct ttgtaatttt
    54781 ttttactctt ttccactaga tttaaaactg ttcctgtgat gcttccattt tttatcttat
    54841 taatcatagt ttgccaccat ttacatatat ctttaactat tttacatact ttatctaata
    54901 tgttaaaaaa agctcccaat attggctcta taattttcca tccagtttcc aacagaggtc
    54961 ctaaggtctc ccatacagtt ttccaaataa cacccagtgt ctctataaaa ttgtttattt
    55021 gaggtgcata ttcacctaaa aaagtaaaaa ttcttgtgat aataggacta acagcttcaa
    55081 ctacaggtcc gattagttgg aatgctgtag ttactattgt accaaatata cttattaatc
    55141 cttgtgcaat tggtgattta ttgtttatac tatctagtaa attatttact aagtttacta
    55201 ctggaagtaa tgaatctatt aatgctgtaa aatcgatatt ttgtaatagt gtacttcctg
    55261 cgttaacaat tgcttttggt gcattcccta tcattgttgc tgcatgattt tcaaaacgtt
    55321 cttgcttatt ttcaaccatc attttacgct tttcagcctc attagaaatt cgatattgag
    55381 tagaatcaga aaactctttt ccatttttta cacttctaga ttgcatctgg tcatatttgt
    55441 tgccaataat tatcttacca ttcattacat tgcctatttt accagccatt ttttcagata
    55501 agccagctaa attgcctaat ccactttcta taaaagtttt tattttcttt agtccttgac
    55561 ctaaaatatc atcaaaaggt ttaacaatac tcttcaagcc attgttaatg cttgtttgag
    55621 ctcctgatat tatacctggt attgtattac tcatttcttt agctaacccc atctgcttta
    55681 cacttatgcc ttccaatgct tcatcaaaag ttttataatt ttctcctacc agagtattaa
    55741 gagattccat gtttcctttt gctgcactta agaaagctgc tgatacatct tgttcactac
    55801 ttgtattcat atttaaagct ctaacatcta ccatagcttg agttatatct ttttcttttt
    55861 tgccaccagt aatattacta atcattttag ctttagttcc cattgcaaca acatcttcag
    55921 ggtcaaaagg cgtatcattt gccattctta ctaaactgcc ataataatca tcaacatcta
    55981 tttgattaac ttttccagta tttcttttca ttacactttc tagaacaact ttctgatttt
    56041 gttcctgacc aagtaaatca acaccctttt tcacagcgac acctatagta gcaccatttg
    56101 tcaaatcaga tatcttccct tttatcgaac caagtattcc acttgccata tcctttacag
    56161 ctattgcacc actccatacc ttacctgcaa ataatctcaa tttgggaaat actttactta
    56221 taatgccact tgccatatct tttatagcta ttacaccact ccaaaaagta tttttaaaca
    56281 acattaactt aggcaaaatt ctacccatag cactactcac catatcttta agattaatac
    56341 ttccttgata aggacgtttc tctacttgtt ttaattttcc caagatacta cttatcactc
    56401 tcttagtcat atcttttgct tttattacga tattccaaat cttgccacca atctttttta
    56461 aatttccaag taatttattt ttagtttttt ctacttcatc acttttagct ttaaatatta
    56521 atataatcat aatatttgaa ttaaactcat ttttcttttg aatcaactta ttaaaataat
    56581 caataatcat agctatagtt attgctagtc tcataatact tccatttaaa cttccaataa
    56641 ctcctgaaac agcatttatg ctagaactta attttgtcat agttgaactt acactactag
    56701 cagtagtttg aacttttctt aacgaggaat ttaaactgtt tactctatta cttgcacttc
    56761 caatagaatt ttttatgcta ctagccatta cattagtgga aagtgaaaca gccacagttg
    56821 ctctcctaaa attatcagtt actgatataa tttgattcat ttttggtgtg taattatctg
    56881 taaggtacat atttatacct tcttctctca catttcccat tacataccac ctcctgtcaa
    56941 aggacacact ccatatccat gtttcatttt ttcaacttct tcctcaattt ctaaggcgaa
    57001 aaaagcttca ataagcttta attcgccttt atccattgca taaaaaaggg acggtcttat
    57061 accttttttc ttccaataat agtacattat tgtagtcctg gtatccgtcc ctattagttt
    57121 tttacctctt ctatcactgc atttttacca taacccataa catcttgaag tattctatat
    57181 aagttggtaa tttcacctgg taataataat tttcttgcta attcttttgg tgttggagcc
    57241 ttaaatttat ccattagctc cttattttta aataaaagct ttccatccaa atcacaaaca
    57301 ccttctataa ttgtaagcat ctgcatctcc ggtaagtcta tatccgtttt catattttca
    57361 tcaattttaa gacaagtatt ttgtatttct tcatctttac ttattgttaa agctctacac
    57421 attactttaa attcctgccc aaatatagtt gataatctct taagttcaac tatagtactt
    57481 ggtctttcta agttttctgt atctgaattt aaaagtaaat ctactatgtt tatatttttt
    57541 gataatccat tttcactcat tattatttgc tcctttatca atcaaattca atcaactaac
    57601 ttttttactt attaactatc tgaatttatt aagtatatac ttactaaata tcagtataaa
    57661 actaaatata aaactaaatt atatcaagaa aatcatactc agtaaatgtg aaaggagctt
    57721 ctatctctcc ttttactcca acctcccaat cagctaaagt taaatcatca aatgctatat
    57781 tttttactgc tattctttct gctccataag aatctgggtc atttaatttt gatatagcaa
    57841 caaatctagg ttcagaacct ctctttatct tttctccaat taacttgtgc attcttgaac
    57901 taacgtggta tagagttatt gagccttttc ctttatatcc catatacttt gtatcagtac
    57961 ccatttgacc tgctattata atatcttctt ttgtaaattc catctttgct tgaaatttct
    58021 ttacttctgc tactttgttt ccatcaagcc aaagttctcc ccaagtacca ctcattacat
    58081 ttctagcttc catatttgcc atattaataa tcctcctata tttctattga taaatctata
    58141 tcttccatag catcaagtac ttttattttt gcttttaaaa atactttaga acctgtgtta
    58201 gcttctttta tttcttgtaa tgtcatataa gataaatcta ctccttttga ttttaaatac
    58261 gatttttgtg cttcaaaatc tatttcaaca gtagaatcag attctataag tgctgatttt
    58321 tctaattctt ctaaataact ttttatagct actatcaata aacatttgtt gtcataactg
    58381 ttagtaacct ttcctatata gtcatctatt atcacctttc ttatgtcact atgtataata
    58441 tctaaagtgt caactatttt tattttctgg aacatttctc ctttttctgc tgttaattca
    58501 gttaaagaat ttactcctct agcaattctt atagctcctg cttctttaat aagtataagc
    58561 tctcctttat taacccttga ttctgcatca actttcgtca tcttaggtat atcgactaca
    58621 tcactaagtt tagtataagt tactgattga cttaaaggtg tacctgctat aagtccagcc
    58681 accctgcttg taaactcatc aacactgtat ttcttttctc caactaacac atcttctgta
    58741 gtaaaattaa ttatcccttc atgatttcct acaacttttc ctaatacagc tttaacctta
    58801 accttatcta tatctctaag tttaattatc caatttttta tagcagtctt atcagcttct
    58861 actgcttttg gcatacatag ataattaaat tccttagtct ctaaaaaatc taatgcagtt
    58921 tgaatatctg cttctccttc tattacataa actaataatt tatttggagt gttaacattt
    58981 cccatcaaag ctaaatttat atattcttta ttttcagcag ataaatcaac tggtatatcc
    59041 tctttttcat gtatttcatt aagacctagt gccttagcat ctttaagtac cattgcaatt
    59101 attcctctag ctgaacgttc tttaacagtt gtagctagct ccttaaatga tatgttgata
    59161 cttggtaatc ctatagccat actatcactc tcctaaattt aaattgattt ctttcatatt
    59221 ttcatatact acatcttctt catatacact atccagatag tttagtgtaa atgtaaagtt
    59281 caatacataa attgactctt cttttttaat actttgttct agctttgtta tatttaattt
    59341 tctgtctgtt acctttatat ttctgttaaa tagcttattt aattcatctg aaatttcata
    59401 cattctaata ctctttgact gtggttttgg taagtatttt atagagataa caatatcttt
    59461 gttattcgta tttaacatta caggtgtaca aataactgat agtatactta caaaaaaaca
    59521 agacccttca gagccttgca cactttcatc atcaataaaa atactttcag taaagttttt
    59581 tttgagaatc tcaataattg tttctaatat ttccttgtat ttaagcaaat aatcaccaca
    59641 ctatcactaa atattcttgc ttaatctgat aatcttacta taaatgatat aagtcatttt
    59701 taaatatata tctcatttat tcctgtcaag tatcttctat atttttaggt aatattattc
    59761 ttttcaatct atcacctcct tcaatatgga tttctttcac aataacatta tctcacatat
    59821 tttattgcct attgttgcaa tggtgtatat aaagtgttgt aaaattgtcc tattttttat
    59881 aatatctcac tcaatttaaa tatcatcttt ttctttaaat tgtagcaaga tgttctatct
    59941 aagtgtagtt tcatagaaat atatgtcata ttgttttttg tcttactatt ataaaaaaga
    60001 ttaaaaaatt ccatttctat atcatttaga cacgttagag cattttctat cttctctttt
    60061 tctatttcta tatcttcttt ttccattttt aattttctta atctttcctc tctttttaac
    60121 acctcatttt ccacagaaga gcttatgtta tatgtgttac tagtcttttc tgtatatacc
    60181 attgctccac atccagagta ttcattctca catcttttta tgtccaagtt aatattcttt
    60241 atctttatat ccaaatactt ataattatgt aatcttttat ctgtttcttt aaataatata
    60301 tcttttttgt tttccatagt acttcccctt ttttatatac ttattattag cttcaaattt
    60361 acaataatct ctttagtgca cagtttttta ctaatctcac aactttcaag aacatattgt
    60421 tctataactg tataaaaaaa acttcttcta tattttgttc taaaatacta gaaatcttct
    60481 tagccataag aagtccagga ttttttatac ctctttctat ttgagatata taatcatttg
    60541 taattccagc ctttctggca agttgaattt gtgtcatacc tttgcatttt ctataatatt
    60601 tcaagttatt tttaaacatt gttttatacc tccattacta ttaagaatat tttgttcttc
    60661 ctcacttaga ttatatagaa ttatttgttc tttatcaata gattttagaa aaaaatattc
    60721 ttttatattt tattagtttt attttttaga acaatttgtt ataatctata cataaggtgg
    60781 tgttataatg tttgccaaaa gattaagaga acttagaaag gaatttggat tgactcaaag
    60841 agaacttgga gaaaaagtag gcgtttccca aagagtctta gggtactatg aaacagaaaa
    60901 cagatttcct gatgaacaca ttttaaataa attggctgat gtatttaatg tatcagttga
    60961 ttaccttctt ggaagaacct tagttaagga aaatattgat acagtagctg cacatagaaa
    61021 aaatccacat gaagagttac ctgaagaagc acaagaacaa cttaatgatt atatagaatt
    61081 tttactaaat aaatataaaa aaaaataaac catatgatga gcagtctatt tttctgctct
    61141 tttaatataa tttaaaggca aacatacatt ctattttagg gggattttta tgaataattt
    61201 ggataagctt tttgaattag cttctcaaga agagataata attcattata ccacttatat
    61261 tgcaggtgat ttagaaggac tatatataaa caaacatggt attaaaatta tatcattact
    61321 cagtaattta aaacaaaact caaaaaaatt gacatccatc ttagctgaag aacttggaca
    61381 tcatttcact agccttggat actatgtatc ctcttataac gattattata caaaaattat
    61441 tatagataag tgcgaaaata aagccttaaa atgggcttgt gagttcttaa ttactgaaga
    61501 agatataata aacataatta actctggcat cacttgcgtt tatgaaatgg cagacatact
    61561 taatgtggat attactttct ttcaaaaaag attagaattt ctatcattaa aaaaacagtc
    61621 tttacaactt ggaaataata aatatttaat attaactaat ttgccgtatt tctacatatt
    61681 tgatccaatt tcataataaa aatagtagta attttaactg gcttaacagt aaaatctata
    61741 tatttatttt aacaaatttt ggtttctata aattcaatat taatatataa taatgatatc
    61801 atattattta aaattctaaa aacaaatata tgcttttgtt aagaaaggtt gtttgatgaa
    61861 tgtataaaga aaagttgttt gataattatt ttaagttctt agcactatta ttttggccaa
    61921 ttatgtggta taagtggata gtaatttcaa atggtactct tgaaaatatg ttatttacca
    61981 tatatgcaat cgtcgcaatt gttttcatca ttttatattc ggtgtttatg ataaaatata
    62041 aagacattac acaaatagat ttcttttaca ggataagtac tctacttgct tttatattta
    62101 cactttttag ctttttaata tacccaaaga gtttattttt cttgtattta aagattattt
    62161 ttactggaat atacctttat tattcaatag taaaaactct taaatttaaa gatgacgaag
    62221 gtgtagtggg tattatgagc tcacttttat taattgtaat aactttgttc tactaaattt
    62281 aattctattt gacttaatat ggctttaaat attagacatc tacattattt tctgatatta
    62341 tttaagatgg tagtcttata ttaataatga aatacactat gaaggagtta actattatgg
    62401 aaaaaaaagt tttagcaaca gttggagaaa aagagataac taatattgat attgaaaatg
    62461 cattaaaatc attagaccct tatcaagcta tgcaatttaa aactgaagaa ggaaaaaaac
    62521 acttattaaa tgatttagtg aatcaagaat tattcttctt agatgctaaa gaagaaaaat
    62581 tagatgaaga agaaatattt aaattagaaa tgaaaaagat agaagaaaat gtattaaagc
    62641 aatttgctat aaataaagtt ttatctagtg ttaatgtaac agaagatgaa aaagtaaaat
    62701 tctttgaagc taataagagc tctttctcta aaccagaaag tgcaactgct aaacatatat
    62761 tagtagatag tgatgaaaaa gctaaagaaa tacttgctca aataaaatca gaagaaatat
    62821 cttttgaaga tgcagctctt aaacattctt cttgcccatc taaagatatg ggtggtgatt
    62881 taggaacatt cggtagagga caaatggttc ctgaatttga agaagctgtg ttctctatgg
    62941 ctaaaggtga agtaagtgaa ccagttaaaa ctcaatttgg ataccatata ataaaattag
    63001 aagaccttca agaaagtaca gagtctacat ttgatgaagt taaggctgaa gttgaaaaaa
    63061 gtttattata tcaaaaacaa aatgaagttt atggaaataa gataaatgct cttaatgcta
    63121 agtacggaaa ccttgtaaaa tacaacgatt aatcataagg tcatatataa aaaagctgtc
    63181 ttttcacaat atttattaga aaagacagct ttttatatta aagtttaaat attcagtttc
    63241 atattatcat tcttttattg taaagaactc agcttaaaag tttaaataag atttttaatt
    63301 atcattagct aaatttttat atccacgtat tatctcataa cagtaaccta ttacatctct
    63361 tctttttatt atcccaataa atgtgtcttg gtcatctata acaggaatga aattttgatt
    63421 taaagatttt ataactaaat cttcaatatc tgcgttgatg gaaacaggag aattatccat
    63481 ttttctattt atatctgtca ctggaacatc ttccaatccc tttaagtcca gatttaaatc
    63541 attttttaat gtccataaaa aatcaccttc tgttatagtt ccaacatatt taccatcctt
    63601 acttattatt ggaattgcag agtatttgtg atattccatt ttttctaggg cttgccttat
    63661 agtgtagtct tcatatatat atgctacttc actttttggt gttagaaaga ataatatgtt
    63721 cattacacta cccaccgtta ctgaaaactt ataaatatta ctcaatattt ataatgttac
    63781 ttttttgcag taactttctc ctttcttatt ttctaagtat tcttaatact atacgctgta
    63841 acaagcgttt ttcctttgct cattttaatc ttattatgct ttattaatat ttttatatgg
    63901 tctatcagta tcacttattc tctttttaga aaatttacta aaaattaatt gacttaaact
    63961 tagccataat aattttactc tacactatta attttaacat atttatctca ttattaatga
    64021 ttttatttta ataattttaa tttattttgc tattaatttt atttacaaaa actgaaaaaa
    64081 ccgctaaatg attagcggct tatctctcat attactagaa cactaatata tatgaatttt
    64141 taattataat ctaactacgt tagcagcttg aggaccttta gctccatcta ctacttcgaa
    64201 ctcaacgctt tgtccttctt ctaatgtttt gtatccatct ccagttatag ctgagaaatg
    64261 tacgaaaaca tctccttcac cttctacaga tatgaatcca aatccttttt cgttgttaaa
    64321 ccatttaact acaccagttt tcattaataa atcctcctaa aaaaacacaa atatttagct
    64381 actcttttct gtaaccttat tactactcta tcatatatag ctatgtttgt caattattat
    64441 tatttttata cattaataat caattttttt actttataat tttaaatgat tattatcttt
    64501 tacactttat ttttctttat aattttttaa taatttattt ttattatatg gaatcttatg
    64561 gacttatcac tccaacctaa atcccatggc accaacattc tatcagtatt atgacaagtt
    64621 accaaaggat accctcttga gtctaatcct gtcactgtcg aaacatgtgt tattctgcct
    64681 ttcttctcat aaccaacaaa atcccctgga cgtaaattat aagcttcttt gtatacttct
    64741 tcataggaac ctttagcaat taatgaacct cttccactat acagtgcata atttttaaaa
    64801 gcttgtgcat ttacccatgc ttttgtacct gctctctcgc tataattcca aattgagttc
    64861 tttttgaacc ttccactttc aaacattatc tgtgatgcaa agtttgcaca atctccacct
    64921 tctggattat aatccctata gtttggatta aatttcatac catgttcttc atcagctgcg
    64981 gctccacagt atttatgtgc ataatctata gccttttttt gttcatctgt aagctgtaac
    65041 tctacaccat cttgttgacc aatataattt cttatatcat cagattttat attttctaaa
    65101 tttaaagagt ctgcaaaagg gtctgtatac cactctttag ttatgacata ttgattatct
    65161 ataattttta catttagata atgatatgta cctattctaa aggcattttc tttgtccttt
    65221 tgattttcat atgaatactt atattcagtc gatactgaac agattatacc atagaggtct
    65281 ttttcttttt cttttatttt tttaatctta acccttgtct ttatgtcttt aaattttaca
    65341 ccttgcttac tagaccaatt ttctaaatac ttcatctttt ttacttcatt ttcataagcc
    65401 cacagaccaa attttttatc cgtctcataa agacctttta aaatgttttc atttttctct
    65461 aatattgcct tatttctgta atcaaataag ttttcaagca atagtttata ttggtctttt
    65521 acatcatcac cttcaacatt tgcagattcc atgacttttt cttccatatt tttcatactt
    65581 aaatcattga ttaaaaatac acctgctgta gtagctaaag acaaaaatac aaatgccatt
    65641 atacctttga tgtacttatt cttatttttc agtattttca aagctacacc tcccaaatag
    65701 tacaccttac aaatcaaatt acaaagaata ttctgtcaca tatagtaatt ttcatattta
    65761 ataattctct attttattat gtccaatatt aaaaattaat tgtatcaata cactgttttt
    65821 tttacaattt tttattttat aatctacttt tttctttttt ttatagtaat atatatgtat
    65881 ataaatattt tggtatcatt ataattaata catactaatg gagggttttt tatgcaaaaa
    65941 aaagtcgcag caattaatga cttatctgga ataggaaaat gctcattatc ggttgctata
    66001 cctatacttt cagcattaaa ggttcaatgt tgtccatttc caacggccat actttcaagt
    66061 caaactggtt atcctgaatt tactttttta gactttaccg atgaaatggt aaaatattca
    66121 aatgtttgga aaaatttaaa agtcaatttt gatagtatat atagtggttt tttgggttca
    66181 aagcatcaaa ttgagatagt ggctaatttt ataaacgatt atcccaatgc ttttatcgta
    66241 gttgaccctg tgatgggtga taatggagtt atgtatccaa tattcacaga agaaatgaga
    66301 catgaaatta aagaattagt taaacattca gatttaacta ctcctaattt aacagaagct
    66361 tgtttcttaa ctggaaatga ttataccaaa agcgattata atagagatga gcttatatat
    66421 attgcaaaat ctgtatctga tttgggacct agcaaagtcg ttattactgg tatattagaa
    66481 gatgataata tattaaattt ggcttacgat agagataatg accatgtatt ctttacatca
    66541 gtcaaatata ataattgttc ttatagtgga actggagata tattcacatc tatactttgt
    66601 ggtatgttag taaataaaca tgatttggga gtagcggtta atactgcaac agattttata
    66661 tataaaacta taaattacac atctcaattt gatactgata gaaatgatgg agttatgttt
    66721 gaaaactttt tatcagattt aactaatata taaagtcaaa aaaactatcc attttataaa
    66781 tacctataaa tcataaaatt taggtattta caaaatggat attatttact aaactattgg
    66841 tatttcaatt gttaccatag caccaccagt tttcacagaa ttttcaatat ataaaatccc
    66901 attatgtttt tgtacaatat tatttacaat atagagtccc attccataat gagatttaga
    66961 atttctactc aaatctcctg tataaaactg ttctgtagct tttgacaaat ctgctttaga
    67021 aaaaccactt ccacaatctg taactacaaa ttttaagtat ttattacgta ctgatacact
    67081 tatgtatagt ttactctggc ttggtgaata atctatagca tttgaaatta tattcataat
    67141 agctctgaat aacagttctc tatctatagt tatattttta ggcaaattat cttgtttata
    67201 aaactccaca tctaagtttt tagtactagc taatgcttct atttgcacta agacatcttt
    67261 tataaactca ctcatactga ttgcttcttt atttaatata tagccattct ctgtttttga
    67321 tatatctatt aaagtattaa tatatttttc tatttgagtg acaccctttg agatatattc
    67381 catgtattct aataactcag gattttcatt tatttcaatt aataagtcag tatttccatg
    67441 tataattgtt agtggtgttt ttatatcatg tgccagtgca gatatctgtt cctttctatt
    67501 ttcttctagc atccattgtt tttctaaaga atcttttaac gccaacttca ttttatccat
    67561 agaaaaaagg acattattaa tttcataaat tttactagat tctacaacaa aatctaaatc
    67621 ctgttgttct attttttctg tagtattttt taaaagctcc atttcaatat taaatttctt
    67681 gccaaatact tttgataata taacaatttc aataaaaaat attatactaa aaataatcat
    67741 acccaatgtc tctggttttg gtaaatatgc tcttaaaatt ggagaactat actctgatac
    67801 tattttgtat tttattataa aaacttcatc tttcttaaaa aactttatat aactttctga
    67861 atatgcatgc ctttcttcaa tatctctcat taaattccat acttcttttg attctttttt
    67921 attaaaggtc cctgaaatta aactcccatc caaagtataa accccatact catatatact
    67981 tggaattata tcttcagtta ctttttcact tgaaataatc tgttctttat atttattaaa
    68041 ttgtttttct gcataattag ctggtaaaat tacacctgat gataataata cagaaaatga
    68101 taacattaaa aggagtacaa ttgaaattgt cataataaag aataaagata aatattttat
    68161 aaaaatagtt cttaactttt caactttttt gttgttagat tttttacctc caagcatttg
    68221 taccctgtcc tccaatagtt taattaattc ataattaata tctaaccagt tttttatttg
    68281 attattttat atctttttat tgctaagtta tattttaaca taataatata aataaacagt
    68341 caatttttac tctattcttc tgatttttta ccttcccatt tagaaaacca aatacataaa
    68401 attacaaatg ctaaaattgt tacaaaacca cacattaaac ctgttgattg atatgctttt
    68461 attgattcaa cctttatata ttcaaccgtt ttagaactcg aaaaagacga ccaaatagtt
    68521 ataaatctaa caccccatgc acaaggaaaa tactgccaaa taccagaacc caatccagtt
    68581 aataataatg ctgaaagtaa catttcaact atacctactc caattgatgt tccttttccg
    68641 aaccttaaac ttaagaataa atgtaatatg tattcaaata aattacaccc aattaaaatt
    68701 agaattgaaa tcatataaaa gcttgatgca aagtaagcct tagatatacc aaatttaaaa
    68761 cctaatacag acactaatgt tgctacaaaa ccaagacata ctaagattat atatttactt
    68821 ataagagtaa gatattttgg attagatgtt gttaacatat gtttataatt ccctgcataa
    68881 tattcttgtt caacaaacat tgaacacaca acacctgaca ataaaggaaa agctattgct
    68941 ataacttgta aatatgctac tatctttagt atattatcag ctcctgaaac cttataatac
    69001 cataaaaaca atcccatccc cattaaagca atgcaaatgt gcattagtat tataaaattt
    69061 ctctttaatt ttattaaatc agaacaaaat attcttatta actgtctcat attacttcac
    69121 ctctctatta ttgaaccaaa cccttgtagc taaagcaaat aatacaaata aaacaataga
    69181 tattaatact cctggcaaaa taacagcatt atttaaaaat tcacttccct ctggtacagg
    69241 aagaccattt ggcagaatat gcaatacaac agccattaat cttgaaggaa tcgaatatgg
    69301 aaacatatac cacatttctg tagttgagaa aacagcaact ccaacaatag taaagaacat
    69361 atttattaga actgtaacaa atataccaaa ttttgaagct aaaaacatac aaagaggaat
    69421 ctgccacata aatagtaaaa taattaatat agttgcaatg atattttgac ctattgaaat
    69481 agtttcttta tagattatcc caacaaaaac tacacctatt gcagaaataa ttgatgctat
    69541 aaaacaacaa ataatacagt aaatcatttt tccagtccaa acgtctttca tttcaattgg
    69601 caatggtaaa ataccacgat atttactttt ttcatctttt aatactatta aagaagatat
    69661 taatgttaat gctcctggaa gaaatgtcgt ataccaccag ttgaaagcag cattttgccc
    69721 tccacctagt ccacataaaa gtatacaaaa cactggaact atccatatca acttcattcc
    69781 aaaagttcct ttcatctttt gaaattccac tctaataaat ctttccatat tactgccctc
    69841 tctttctatt ttcagctaca actttcataa aaagtttttc taagttttgt tcttttgata
    69901 cttctccttg ataacccatt actccattag aaattattcc tatttcatct acaacttgtt
    69961 caacttcaga caagatatgg cttgataaaa taactgtaat tccttgtttt ggaaaagaac
    70021 gaatcaattc tctaagttct tcaataccaa tagggtcaag accatttgta ggctcatcta
    70081 agattaaaag ttttgggtga tttaataatg caatagcaat accaaggcgt tgcttcatgc
    70141 ctagagagaa ttgacctgaa cgctttttaa aggtatctct taaatctaca gtctctaaaa
    70201 cttcttcaat gcgagagtca ggaagaccaa gtaaagtagt atggactttt aaattttctc
    70261 gtgctgttaa attctcatat atagcaggag actcaataag agaaccaata tttgataaat
    70321 cctttctagt ccatctatgt ccctcaaaca ttatttttcc tgaagttgga tttaaaatcc
    70381 cagttatcat ttttaataaa gtagatttcc cagctccatt tggtcctaat aatccatata
    70441 tagaattaga tttaattgct agtgaaatgt tatcaactgc catctgctcc ttaaattttt
    70501 tagaaactcc ttttacctgc aaaatataat tactcataat tttcatcctt tcttttgtca
    70561 aacttattta caagaatcat tctaaatcat aaatataagg attttataag aattaaaaaa
    70621 caaaaaaaga tgtgttaaaa acacatcttt ttttatctta attctattaa ttttccattg
    70681 tagtatatct ctacttcttc aatccaaatg ctattatctt cttcttggat gacattttta
    70741 ataatattat ttatagtata tattatattt tgttcattca aataatcatc tttccaagaa
    70801 actctacttt ttttatctgg ttctatcaag tttattttaa caagattatc tttttcctta
    70861 acttctactt ccatgtctaa accattaaaa tactcatttg ataatgtatc taagattaat
    70921 cgcagtttat ccttaagtga actttcttca tcaatctgta agtactttac tattttctca
    70981 tcctttgaaa ttatctctat aggtatttta gtagtttttt tagaattaat cattttacta
    71041 gttgtttctt cttttgcatc ttcatccttc tttacaactg ctgattcttt agaatcaact
    71101 agctcaactg cactgatgct ataatccata catgccgtac tcaataaagt agtagcaatt
    71161 attaaaaaac ttactgctat tttattcata agtatccctc tcctaattct ctttcgatac
    71221 ttattatacc atagtataga ttatattttt atacttttaa atcaatttat aaattattat
    71281 agtaaattat ttacaattct aagctatttg aatttatttt tatagtatat tctttctcta
    71341 aattcgacag atttttattc aaaagccctt ttatttctct cgtatttcta tacttgttgc
    71401 tatgttcttc actatgttca taatcatatg aatcattgtc atattcttca tcattattaa
    71461 attcttcaat tgcttctttt gactttatat cacaattaaa tttatactta tttactggta
    71521 tatcaagtct taccttagaa tttggaactt ctatgtccag gaacttagca attggcatat
    71581 cagagtacaa gtaaaattca ctttcataat ttgaatttct acctattttc tcttttatat
    71641 ttacattttc aggtatatac tcttctatat tattgataaa tacatcttca ttctctgaag
    71701 atatatacaa tgactctgat tctatgttta catttttaac gcctaaaatt gattttgttg
    71761 acaagtgaag attgttatta gatattaagt ttaggttttc taatctattt actttgttct
    71821 ctgttatagc tctactaaaa cctccataag aagttttata tgttatagta tttgaagcta
    71881 cattatcgta tacaaataag tgtgagctta tacttgatgc atttatgtct acattatttg
    71941 gtacatatat tataatttct ctataatcat gtgaaaacat actatttata gatgtattta
    72001 ataattggtc gaaattttta atctttttaa ttttattttc atattttctt tcacctttta
    72061 caactaaagt cttatctttt aaagttacat tgtatttgta aaactcatta tttcctcttg
    72121 ttgttacacg cacatcttca cttgaacttt tctttattgt aacgtttata ttgtcaacag
    72181 ctatatctaa cttgtcaata tttacttttt cttgataaag tttattttct tttttaaatt
    72241 cagcttcctt ttctaaacca aagtttatta ggcttggcat aactaaaatc cctgaccatg
    72301 ttgtccctat tatacctatt accaataaaa ccgcagcaaa tatagcaagt tttttattca
    72361 tgtttatctt ctcctttctt attttctata tcttcaaggt ccttatatat cgcctcaaaa
    72421 tttatactat catcattata ttcatcagtt tcttttatgc tttcttcttc tctattgtag
    72481 taatcattat tatatgaatc ttcattaatg tctttattca aatcttcatc atttaaagta
    72541 gctttttttc ttttttccat cttttcattt gcttttatat aaatattttt tctctttatc
    72601 caatgtatat aattatttag taattgttta cctagtttta tggcaaataa taaaatttgc
    72661 catgcaagta tctcaagccc tacaaatgct atggttgcga aaatacaaaa catcataaca
    72721 tctggaacca ttgctataaa tttaatcaca aatggaatta atataacaaa agcaattaat
    72781 gagcatacta atgcaatagt agcagataca atagcacata caaacgcaaa tgctggaaca
    72841 attagaaata aagataacac tactaataac ccctttataa cttgtctgga taatcctcct
    72901 acaccttctt ctatacttgg tgtaagttta tcatttatat tttcttttga tttattgtac
    72961 ttttccttag cttcatcttt caagatagaa taatcctttt ttacatttga tttaaatcta
    73021 ctaaatttac catttaatat gtctgtattc attatttttc catctatatt ttcttttgat
    73081 ttactatact tttcttttgc ttcatctttt aagatagagt aacctttttt catatctgat
    73141 ttaaatttac taaacttatc attcaaaaca tctgtattta ttattttttc ctcttcaata
    73201 tttttttctt tagtttgtaa gataagttct tttgctatag attttggtga gccaagtgat
    73261 gctattatct ccatatcact ctttccctct ataagaccat ctacaaaata ctcttcataa
    73321 tctctcaata tatcattaac ttcgctctca gaaaaatctt tttttagata atcctttaaa
    73381 atttcaagaa actcagtttt attcaagttc attacctccc tcatcttcac ttattaaaat
    73441 ctcaacagcc tttacaaatt ctctccactc ttccatcaga ttggataaat tctcttttcc
    73501 tagtgaagtt attctatagt attttctagc aggaccttca ttagattcta gtatatatgt
    73561 ttcgaaatac aaatcttttg taagtcttct tagaatagga tatattgttc cttcatttac
    73621 atctattact ttagagatgt tatgtactat ctcatatcca tacatatctt tcttagatat
    73681 gagagcaagt acacaaattt ctaaaacacc ctttctaaat tgtgtgttca tatactccat
    73741 cctttcttta aatacacagt attgtgtttt acaaggtact atgttaaaac ttcttatatc
    73801 ctcataataa cacagtacta tgttctgcac aatagttatt tttaaatatt cttgttgatt
    73861 aaatccttct ataaatgtat aatactctaa tcagatatat tttatgaaag tggtgataaa
    73921 ttggctaaaa tgaaagatga taaaacaata ttaatcctaa ctgctcaatt tggtgctgga
    73981 catataagtg ctgcaaaagc agtcaaagaa tgtattattg aaaaatatag taactataat
    74041 gttgttatac aaaactttat aaatgcaagt attcccatga tgaataagcc tatggtaaaa
    74101 ctttatgaaa acaatacaaa atatactcct ggattatata attactatta ttactttaag
    74161 aaatcgtttg attcaagaca tgatttatct cataaattat atacacctaa actttctgag
    74221 tatattgctg atataaatcc agatttgatt atctctacat ttccactagc tgctgcttgt
    74281 gtaaataact ttaagataaa aaatcctgat ataaatatac ctacacttac agttataaca
    74341 gatgttgtag atagtatgga atgggttttt gaaaatacag atttgtattt tgttccttct
    74401 cctgaaataa aaaatagatt ttttcagaaa ggaataaatc ctgactccat aaaggttact
    74461 ggagttcctg ttgataagag atttcaaatt gaaagtaaag aactatgttg tgataaatat
    74521 agactattac ttctaggtgg aggaagaggt ctatttgata tagatgagga ttttatgcat
    74581 tggatagatg aatttattga agaacatagt aattctatag aaattacaat agttactggt
    74641 aaaaacaaaa aattatatga caatctaact cataaaaaac ctctaaaaaa tattaaagta
    74701 cttggatttg taaacgacat gtataatcta ataagagaat gtgacctaat gctaactaag
    74761 cctggaggag caactatatt tgaagctatt caatcacaaa ctccagtact cgtaaaaatg
    74821 ccaaaagttg gacaagaaat tgaaaacgct aaatttataa tagataaggg tcttggcatg
    74881 atttatagtg atgacctaga ccttaaaaac atattttata aattagtatc aaatgaattt
    74941 gattctataa taaactttat gaaaaaaaat ttaaaagaat ttaaaacagt cattcatcca
    75001 gagaaaattg ctgattatat atcagaatta atagataatc attacagtta aattgtacta
    75061 ttaaaaaatt tcaaacataa aattaaaggc aatcaagtat gattttacac ttgagaattt
    75121 actcatagtg tttaataata cttgattgcc tttatcatat caaaatcaaa ttgttatatt
    75181 agtatatatt tttcttgtac tgcatataca gttgttgtat ttcttccata cttctcttta
    75241 attctatttg taaatctgaa gcagtctggt aatccttatt ttctatagct tctctcactc
    75301 tagtgaatag tgattctcta gttaaagtat ccttcataat attgaacttt aaatccgata
    75361 ttgagttcca aactacctca tcaagcgcat ccatattttc ttttgtgtgt atcttgacaa
    75421 tacttcttat tttttgaatc ccagcctcta ttattctagt ttttaatttc ttttgccact
    75481 tatctatagc tccaatctta aatgattcta ttatactatc agtaaataca tcaccttgtt
    75541 ttaaagattt taattttgaa gcatatattt ctaagttttt catattttca taaactgtag
    75601 ctggtggtat tccaaatctt gcatttcttt cttccaaact ataatgttca aatacatcat
    75661 tttcatctct atatgctcta tctttttcta aatagaaact ttcttcacct acatttttag
    75721 ataactcttt ttcaagttct tttgtactaa gaccactctt agctgctgct tttataccat
    75781 ccaacattgt ttgataacat cctgctatta ctaaatacgt gttagataga gggcttggtg
    75841 accttaattc aaatcttaca gtctttggat ttttcatatc tcttattaat ccaacaagca
    75901 ctgacctatt tcttgatgga atctcataac tatgccctaa agatgtaact atacatacag
    75961 gagcttcaaa tccaggaact aatctattaa atccatcatt agaagctgtt acaattgggt
    76021 ttaatacttc ataattgtaa agaagtccca taagagcccc atatcctagt tcacttagat
    76081 aatcttcttt taaatctttt ggagcaaata gattttttat acttccatcc tttaacttcg
    76141 cacttactcc tacatgtgta tgtccaccac ttcctgctac tccatgaatt ggttttgctt
    76201 taaatgtaac ttctagtcca tgtgatgtaa atacatcctc tataacatct cttactaata
    76261 attcattgtc tgctgcttgt aatggtgtag aaaacttcca agaaacctct aattgctcca
    76321 tagcatggtt tgttcttcca tctatactaa tagaactttg tattcctccg acctctttgt
    76381 gagccatttc agggtttaca cctagctttt gaagtataat taaacttttc tctaaacaag
    76441 ttcttataat accatgagtt cttttccagt attgctcttt taggctttgt gatacatata
    76501 atttctctaa gtcagcttta tcctcaggag tattaaccca gaactcaagt tctgtagctg
    76561 ctgttaacat tatttcctct atatcatcta ctgaatctat tcctatgtta tttattacat
    76621 gtggatattc tctaaatatt tcatacattg actttttaaa gtacttatct gctttttgaa
    76681 gtactcctct agaacatact tttttattat catgtattaa aaatgcaggt atctttaatg
    76741 ttccaacagg tagacctact tcttcgtcta tatattccat attgtaatct acataccaat
    76801 gacaactttt atctggcatt aaatctactt tcgcattatt taatgtagct atattataaa
    76861 gctcaacact tgaaccatca gtctgtatag ctgattccaa aaatttatct atatcctcca
    76921 aaaataattc tacaggaatc ttttcatctg ttgcatttcc tcctaaatca acccccatta
    76981 aggaaacaaa tcttatattt ttattgcttt ttaggatttc tcttaattct tcattagtgt
    77041 gtttatcttt ctctattacg tataatagac tatccatttt tccactctcc cataattttt
    77101 atgtatattt tattttgtta aatacaagat aaatttcatt ttccttacat ttatgaattt
    77161 ttcttgcaaa ttattcgtgt tttattcgtg tttttattta tattattata tatcaagtat
    77221 aaaaagttcg caatattttt tattggaaaa aatattatac atacaata
//
LOCUS       DAEPKC010000005        76402 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.005, whole genome shotgun sequence.
ACCESSION   DAEPKC010000005 DAEPKC010000000
VERSION     DAEPKC010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 76402)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 76402)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..76402
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.005"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(6..467)
                     /locus_tag="KR294_000423"
     CDS             complement(6..467)
                     /locus_tag="KR294_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0238540.1"
                     /translation="MQIEQLDLETRNKIYCYTKKILRKYQKGITSGKLTADKFADNIL
                     SQDFISSILNEKIVNETNFKISYRNYIETLINIQNENLSNLRKKSTKTAKCFNISQIT
                     QLKNLLSNTGYNLLIPYKYLTARDIEGIVTLINTGSIELGNERIYNYISKA"
     gene            650..1117
                     /locus_tag="KR294_000424"
     CDS             650..1117
                     /locus_tag="KR294_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0238541.1"
                     /translation="MKMLNGIIKLFYSEIVKTKINNLDSSGYSLRDECKEIRNITLKI
                     DSVFFKLLKLAFGSILLMVAFNLNMVLGIGVFLVGVVYILYKRNMEEQVKEHINNVKN
                     NIDISKITFMDEKGRTGLNALITLLLIGLLTGFNWILVASFVVVFVFTIKNVC"
     gene            1160..2923
                     /locus_tag="KR294_000425"
     CDS             1160..2923
                     /locus_tag="KR294_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpoIIE family protein phosphatase"
                     /protein_id="HBH0238542.1"
                     /translation="MTNGSYKMKNLVEISAMVTESTDFFNIKDDIIEKMLEVVHPTKA
                     CVNLFYKNDSKYAYLVCSQTLEYVPQIFPINSLKGAKIDFDTYPEYIHEAVNEKKIIY
                     VENVFEDSRAEGERDLAKAEGYIGRIVFPFIINNVVVGFMTCFLKEDDYITEQDIDFI
                     SSVASLLSLSIEITNKNNNVQILIDKLRGSISAINEATKKLYLNKSIDGFLENLSKQA
                     CNITNSKEALIIINSHHNKDAIVSCYNVEQKKKTNLYPMIDMFLKKESLGGYLNNLKP
                     CSKKGINLESYIYYKLQDKNETIGCIVCANSKNYTSDDLNILSILSKQVSVGMQLYEH
                     NEKEVKHKVLENELNILNKQQQLIMDKGKMDCNDEKELYFYHKPARVVGGDFYYATKV
                     DDEHIVYIVADVMGHGMVSNYVVAMIKGAFKVLCNQYNTPREIMTNLNRMLYDEFDKM
                     GVFTTCLIGIIDTKENMITVSNAGHYSPVVVKKDGTIENNLNCKKGIPIGIMEDATYE
                     NNTLSMEDYAMVCMYTDGILEIKNSSKEEYGINRLENFLKENFRLNQQLIVENLKLDL
                     KNFSSKDNYDDDILIVMLKDR"
     gene            2931..3539
                     /locus_tag="KR294_000426"
     CDS             2931..3539
                     /locus_tag="KR294_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBH0238543.1"
                     /translation="MDSNDKKGLKSPEIIIINGSPRINKNCSFIANEVKAMLEECGLS
                     CKIFNIYNMDIEYCTACGFCEKTGYCKFNDDMKPLYKMFDDSKGTIVISPVHFDSISA
                     KLKTVVDRTQAIYASKYVLNKPSIDRSKKRIGMYIAVGGSKSYDSQFKGGQIVMDFFF
                     KSINTKLLHNIYLNNTDDVSYIDNQEFKDIIYKNLKIYIDSI"
     gene            3611..4180
                     /locus_tag="KR294_000427"
     CDS             3611..4180
                     /locus_tag="KR294_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate propanoyltransferase"
                     /protein_id="HBH0238544.1"
                     /translation="MKLPIALSNKHVHLSQADIDVLFGAGHELTKFKPLSQPGQYACE
                     EKVDLVGPKGTLKGVRVLGPARAHTQVEISLADGFPLGVKAPIKESGDIAGTPGVKLV
                     GPAGEVEMKEGVIVASRHIHMSNEDAAKFGVTDKQIVKVKTSGPRALVFENVLVRASD
                     SFNLEMHVDMEEGNAAGVKNGDLVELIVD"
     gene            4698..8237
                     /gene="nifJ"
                     /locus_tag="KR294_000428"
     CDS             4698..8237
                     /gene="nifJ"
                     /locus_tag="KR294_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HBH0238545.1"
                     /translation="MAKFMKTLDGNTAAAHVAYAFTDVAAIYPITPSSTMAEVVDEWA
                     SQGRKNIFGQTVNVVEMQSEAGASGTFHGSLQGGALTSTFTASQGLLLMIPNMYKVAG
                     ELLPGVFHVSARALASQALSIFGDHQDVMAARQTGCVLLASGSVQEVADIAPVAHLAA
                     IEGRLPFIHFFDGFRTSHEIQKVELLENEDYASLLNFEAVQAFRDNALSPNHPVARGT
                     AQNPDIYFQTREASNKYYQNIVGIVEKYMEKMSNLTGRKHSLFDYYGAEDAKYVLIAM
                     GSVTETIEETIDYLNAKGEKYGLVKVHLYRPFSMKHFLDAMPSTVERICVLDRTKEPG
                     STGEPLYLDVRDVFYGKENAPMIIGGRYGLGSKDTTPSDIKTVFDNLVSEQPKNGFTV
                     GIVDDVTNTSLTPSEPIKIASKGTIRCKFWGLGSDGTVGANKQAIKIIGDHTEKYAQA
                     YFDYDSKKSGGITMSHLRFGDTPIRATYLIDEADYIACHKQSYVYQYDLLKGLKKGGT
                     FVLNTIWDQAGLEEHLPAHMKQYIAKNDIKFYTVNAVKLGQEIGLGNRINMIMQSAFF
                     KLAEIIPEEDAVKYLKDSIVKAYGKKGEKIVNMNYAAVDAGINALVKVEVPASWENAV
                     DADKGEVKEPEFIKNILRPMTAQEGNNLPVSTFNGIEDGTFPCGTAAYEKRGIAVDVP
                     EWIIDNCIQCNQCSFICPHSCIRPVLVTEEELANAPEGFEAKKALGKGLEGLKYRMQL
                     SPLDCTGCGNCADICPAKEKALVMKPIDTQLDTELDNWAFAVNPDEVAPKGDVMPANT
                     VKGSQFRQPLMEFSGACAGCGETAYIKVVTQLYGDRMMIANATGCSSIWGASAPSIPY
                     TCNHEGKGPSWANSLFEDNAEYGFGMYTAVKQIRNKIVDAMTELVSMDICEDAKAVFT
                     EWLDSRNDGEASKVASAKVVELLEKPACDCTDEKAKELVKAIKDRKDYLVKRSQWILG
                     GDGWAYDIGYGGLDHVLASGEDVNVLVFDTEVYSNTGGQASKATPAAAMAKFAASGKK
                     SRKKDLGMMAMTYGNVYVAQVAMGADKNQFIKAVIEAEKHDGPSLIIAYAPCINHGLK
                     EGMGRTVANEAQAVACGYWHLYRFNPEVKAEGKNPFTLDSKEPTASFKDFILAQVRYS
                     AIAKQFPEEADGLFAKAEADAKERYEGYKKLAE"
     gene            complement(8629..9525)
                     /locus_tag="KR294_000429"
     CDS             complement(8629..9525)
                     /locus_tag="KR294_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein"
                     /protein_id="HBH0238546.1"
                     /translation="MMRRNIPTKLKTILALGVLTLATASSAVTASASSLENNVNISNK
                     SLVYSNTKYKFSAKPNCSVKPELKPDKDNSCKDKNHNDKNCNNTNKPEDNNNSDSTNK
                     PGNNKPESNKPEDNNNSGSTNKPDNNKPESNKPEDNNNSGSTDKPEDNNNSDSTNKPD
                     DNNNSGSTSESFSAYQKEVVDLVNIERAKAGLNPLTLDSSISNVATKKSQDMIDNNYF
                     SHNSPTYGSPFDMLKKFGISYKTAGENIAMGQKTPKEVVNAWMNSEGHRKNIMNPNFS
                     KIGVGVAQKSGGSIYWTQIFVG"
     gene            complement(10021..11355)
                     /locus_tag="KR294_000430"
     CDS             complement(10021..11355)
                     /locus_tag="KR294_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HBH0238547.1"
                     /translation="MSIIAPIGIIIGIIAIIYFSVKEIHITIAAPIATLIVVILNKMD
                     VVTSMLGADKNNYMGALGNYIMSYFAIFLLGSILAKFMEESGATVSIADFILNKFGSN
                     HPYRVLVAIFIVSFILTYGGISLFVVMFAVIPLARTLFKKLDISWNLIQIPLWLGIAT
                     ITMTIIPGTPAIQNVIPIQYLNTSLTAATIPSIVGSIGCATFGLVYMKYALNKSIRKG
                     ETYATYTSELEEESLDRELPGFFASIFPLLALVIIAITGSTFGSEFMKKNVIYIALIV
                     AILLSAFLFHKFLSSKIQTLSIGASGSIGPIFATSSAVAFGAVIMAAPGFDVFSKLIM
                     SIPGSPLISLTVLTSTMSAITGSSSGALGIVMPNFADYYLSTGLNPELIHRVATIASN
                     ILTIVPQSGVFLTFLSLSKLTHKTGFKETFIVVAVGSLIAEIIVITLGLLMY"
     gene            complement(11417..12193)
                     /locus_tag="KR294_000431"
     CDS             complement(11417..12193)
                     /locus_tag="KR294_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxybutyrate dehydrogenase"
                     /protein_id="HBH0238548.1"
                     /translation="MVKDKVVFVTGAASGIGKQIAESFLKNGAKVMFSDINQEALNNT
                     ITELQKKGYDCMSVKCDVTKEEEINHAIDKTVEKYGRLDILINNAGLQHVSMIEDFPT
                     DKFEFMIKIMLTAPFIATKKAFPIMKKQGFGRIINMASINGVIGFAGKAAYNSAKHGL
                     IGLTKVAALEAADSGITVNALCPGYVDTPLVRGQFNDLSKTRNIPLENVLEEVLYPLV
                     PQKRLLDVQEIADYAMFLASDNAKGITGQACLLDGGYTAQ"
     gene            complement(12298..12963)
                     /locus_tag="KR294_000432"
     CDS             complement(12298..12963)
                     /locus_tag="KR294_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacid CoA-transferase subunit B"
                     /protein_id="HBH0238549.1"
                     /translation="MDKLEMQEYIANRVSKELKDGAVVNLGIGLPTKVANYIPDNVNV
                     ILQSENGFLGLGSAEDGNSSDETIVNAGGQPVTILPGGCFFDSATSFGIIRGGHVDIT
                     VLGALQVDKYGNIANYMIPGKMVPGMGGAMDLVTGAKKVIVAMEHTSKGSAKILNNCT
                     LPLTATNAVDLIVTEMGVMEVTSDGILLKEINPAFTLDDVISATEAPLILSDSLNGKI
                     SVV"
     gene            complement(12963..13619)
                     /locus_tag="KR294_000433"
     CDS             complement(12963..13619)
                     /locus_tag="KR294_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase subunit A"
                     /protein_id="HBH0238550.1"
                     /translation="MNKIVSIDEALSHVKDGDTIMVGGFMANGSPENLIDYLCSKNIK
                     DLTLICNDTGFIDKGVGKMVVNKQFKKIIASHVGLNKETGRQMNNNETDVELVPQGTL
                     AEQIRAAGYGLGGILTPTGIGTLVEEGKQKIVVDSKEYLLEKPIYADVALLFASKVDK
                     AGNLVYKGSMNNFNNLMASAAKITIVEADEIVEIGDIDPNEVNTPGIFVNYIIEGGNL
                     "
     gene            complement(13628..14806)
                     /locus_tag="KR294_000434"
     CDS             complement(13628..14806)
                     /locus_tag="KR294_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000786547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HBH0238551.1"
                     /translation="MKDVVIVSAVRTPIGSFGGVFKNTSAVQLGTITVKEAISRVGLN
                     LSEIDEVIIGNVLQTGLGQNVARQIAINAGIPNSVPSYTVNKLCGSGLKSVQLAAQSI
                     TSGENDVVIAGGTENMSQAPYIVPTARFGSKMGDITMVDSMLTDGLIDAFNQYHMGIT
                     AENIATKFEFTREMQDKLALESQSKAENAIKNNRFKEEIVPVDVLIRRGKIETIDKDE
                     YPKLGMTFEGLAKLKPAFKKDGTVTAGNASGINDGAAMLILMSQQKADELGIRPLAKI
                     KSYASAGVEPEVMGTGPIPATRKALKKAGLSINDIDLIEANEAFAAQALAVKNELQID
                     SSKLNVNGGAIALGHPIGASGARILVTLIYEMQKRKVETGLATLCIGGGQGISMVVSR
                     "
     gene            15161..16063
                     /locus_tag="KR294_000435"
     CDS             15161..16063
                     /locus_tag="KR294_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBH0238552.1"
                     /translation="MDIKQLKYFVEIVKSGFNLSIASKTLHISQPALSQIIKNFEESE
                     DVYLFERYKGRLNGLTPAGERFYVNAEHIINEYKNMMEDLREDSVQFKGKVRIGIPPL
                     ILGIAFSDVVAQLVANNPDIEFDIVEKGAYDLNRMLILQELDYAVLLHPHKIDKSVVT
                     EHVLQEDELTAFLNINHPLAKKDKIDWNDLNEQLLAIFNPTFMIHHKLMQKFTDENVK
                     LKRYIMSGSWDFLLLSTTNSDFITILPSPVHDFFENSKIIEKPFNHPITWKVILCRPK
                     KERYSHVDQHVFKFIIDFFSKKNS"
     gene            complement(16279..17091)
                     /locus_tag="KR294_000436"
     CDS             complement(16279..17091)
                     /locus_tag="KR294_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0238553.1"
                     /translation="MFTSILKKLKKDKSFAFACITLSIIIILIIASFILNIDSNAIDT
                     TSKLQEPSLKHIFGTDELGRDYFSRALYGGRISLSVGILSMLISVVFGTAVGVISGYI
                     GGKLDQFLMRLIDMLMSIPSFLVLIVLNTYLTPKVSTIILIIGFLSWMEVSRIVRGET
                     LKIKENEYCLAAKATGIKTRNILLRHIVLNLKETIVVAGSLNIANAILTESALSFLGL
                     GIQLPLASWGNMLQDAQRHIFDKLYLAVFPGLLIFLTVMSLTIISKKFSSNT"
     gene            complement(17094..18053)
                     /locus_tag="KR294_000437"
     CDS             complement(17094..18053)
                     /locus_tag="KR294_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0238554.1"
                     /translation="MLKLILNRVKVLIPMLILISILSFGLLELAPGDPADAYINPLMS
                     SQDIENIRVNMGLDKPVYIRYLNWLKNTLSGNLGISYINHMPVTEQIMEKMGNTFILM
                     GTSLIFSILVAIPLGIFLAVNKNSITSKVSSVFNYIGVSIPSFWIGMILISIFSVKLN
                     IFPSGGMHTIGNDSIGDLVKHLVLPVITLGLYNTAIFTNYVEASVNEQLKKQYVITAR
                     AKGLSEKVILFKHVLKNSLTSLVTILGMSIQKLVTGAFVTEVVFSWPGMGRLMIDSIF
                     SRDYTVIMAITMLSALFLILGNLVADILYLLIDPKIKSSKGGF"
     gene            complement(18159..19718)
                     /locus_tag="KR294_000438"
     CDS             complement(18159..19718)
                     /locus_tag="KR294_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBH0238555.1"
                     /translation="MKFKKLASLILVSSLMLTFTACASNDKDKSSGSKSGGTVVIPMA
                     SDPDIINGAFANVKEDSLASNIVYAPLYTYEKGNLVNYLAEKVDFKDSKELTIKLKSN
                     LKWHDGKPITAEDVLFTFNTVLDEKQNSPSRQYLLVGEKPVKVEKIDDLTVKITLPTA
                     SESFLYGISKISPIPKHVFEGESNIAKSEKNNNPVGSGAFKFKEWKKGESIVFEKNAD
                     YFGGEPKADSIALKIIPNEASQEAALNNGEISLMKTSAEGYEKAKSNSNLQTYTYSEE
                     RLNYIVFNQNISNMANKEVRQALSYALNRNEMIESAYGKEGSVPAKSILVPEADFYTE
                     EGVEGYDQDTNKAKDLLDKSGVKIDKLKIGYNTGRFGHKNYALVAQQELKKIGIEAEI
                     VPYESKAFFNILFSNSTECDMYVNGYAWGLEPNPYRGMFETGQYCNQTKYSNAEIDAL
                     WEKGFTELNKEKREEIYKQIQQDISKDAPIYTIDYEQNLMAAQKNLKGIKDAKPSPAI
                     LFEDWSKLYVE"
     gene            19937..20914
                     /locus_tag="KR294_000439"
     CDS             19937..20914
                     /locus_tag="KR294_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0238556.1"
                     /translation="MSKALIEVKDLKVYFHTDKGIVKSVNEVSFNINEGETIGIVGES
                     GCGKSVTAMSLMKLLPTSKIEGGEIIFRGKDILKMNEDELMGIRGNEISMIFQEPMTS
                     LNPAFTVGSQIIEGIMIHQDLSKEEAKKKVIDMIKLVEIPRAEEIYNSYPHELSGGMR
                     QRIMIAMALSCNPKLLIADEPTTALDVTIQAQILDIMKNIKEKLNTSIMMITHDLGVV
                     AEMCDKVLVMYAGKIIEVAEVVELFKNPKHPYTIGLLKSKPALGKNKDKRLYSIPGQV
                     PNPIGMPDSCYFSDRCEKVCDKCRTQIPPLIELNSGHSIACWLYKKEEI"
     gene            20915..21886
                     /locus_tag="KR294_000440"
     CDS             20915..21886
                     /locus_tag="KR294_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide ABC transporter ATP-binding protein"
                     /protein_id="HBH0238557.1"
                     /translation="MKKEESLLKVEGLKKYFEVKSGLFDKKIKSVKAVDGISFDLKKG
                     ETLAIVGESGCGKSTAGRTILRLIEKTEGKVEFNGVDIYKLEKEELRKLRPKMQMIFQ
                     DPYSSLNPRLNVEQIISEAVIEHNLVPKNEIKDNILNVVESCGLSKYHLNRKPGEFSG
                     GQRQRIGIARALALNPEFIVCDEPVSALDVSIQSQIINLLMDLQDKYKLSYLFISHDL
                     SVVNHIAHRVCVMYLGSIIEIATKGELYLHSQHPYTKALMSAVPIQDPTIKKNRIILK
                     GDIPSPTNPPSGCKFHTRCPYCKEICKKEIPVLKEISRNHFVACHLV"
     gene            22038..24080
                     /locus_tag="KR294_000441"
     CDS             22038..24080
                     /locus_tag="KR294_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HBH0238558.1"
                     /translation="MSILVTLLGLLVCTTISTVFSKKWSNIPLAIYQIVLGIILSILP
                     FKFSFSFNPEIFVICIIAPLLFSEGQNVSRKELLELRKPILLLAFGLVLITVFAGGIF
                     IHFLIPGMPLSVSFALAAVISPTDLVAVKSITQGLNFPKNIMSILEGESLLNDAAGVV
                     AFKVAVLATVTGVFSIEEAGIQFMITAFGGIIVGSILGYIIIKIRLSLHKWNLEEIPM
                     VIVIQIMTPLFVYFVAEEIGVSGILAVVMAGIAHGIEKEHLQNTTTKLRIISDNTWYV
                     LEYVLNGFVFTLLGFLLPSIYTGLSSKNENMALELTFISTLIVLILFVIRFIWVYLWH
                     NSFIKPKKNPLNNFFVGFLGFKDEEVIKESISKCKYSLIVATCGVHGTFTLATALSIP
                     FYLADKDVFPMRDTVLFISSEVILISLVLATILLPRLLKNNVQESEPLLSDKEAYKLI
                     LKEAILKLSNEKAQEVQPVIHDLNEQLVDSEKGILNTPDNKLISMMIAEADQQGLLAV
                     LKLLEDGKISDRAFKLYRFYITKSRKSVQKSIFKIVKLKISMWIINRKVKKEVKEKIT
                     KIVSENKEIIKEFHHAYALSTKTAISFINKNTDEDNRHEALIAIRFYNRYLNWITRKI
                     QNDDKFEARVEYYRVMAIQSQRDSVQQLVETKQISREVAKELLENILYDEMMMIES"
     gene            24341..25183
                     /locus_tag="KR294_000442"
     CDS             24341..25183
                     /locus_tag="KR294_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBH0238559.1"
                     /translation="MIIQQIYNNNVVLVLDENIKKELILTGCGIGFQKKKGQEIDKSK
                     IERTFVIQDESFLDKISKLASQVDEKFFEVSTEIIAYAEENLNTKLYEYIYVALTDHI
                     AFAIKRYHENITIKNDLLHEIKRIHKKEYEIGKWAVDYINKEFDVKFPVDEAGFIAMH
                     IVNSNYKGSSKESLLITKIVKDILNIIRYYYRVEFKEDDINYDRLLTHLKFFAKRLVK
                     KEKINDTNNEIIDIIKVKYEKDYDCAYKIKTHVEKNYDYYVSQDELLYLTLHIKRVIS
                     VLNL"
     gene            25486..27558
                     /locus_tag="KR294_000443"
     CDS             25486..27558
                     /locus_tag="KR294_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBH0238560.1"
                     /translation="MKKVFGVLQKVGKSLMLPVALLPAAGILLGVSNALAGDALLAHF
                     PALANPTFQLIISIMESSGQIIFNNLPLIFAVGVAVGLTEGEGVAALAAIVGFLILNT
                     SMGVMAGVTEDMVDNSMYANIVGIPTIQTGVFGGIIIGIVAAYLYKKFYKIELPQYLG
                     FFAGKRFVPIVTSLVAIAIGIILSFIWPPIQEGLLSFSKNVIEANQTLAAFMEGSLER
                     LLIPFGLHHVFHNPFWYQFGEYVNKAGELVMGDQKIFFAQLKDGVNFTAGTFMTGAFP
                     FMMFGLPAAALAMVHEAKPEKKKFVAGIMASAALTSFLTGITEPIEFAFLFVAPVLFA
                     IHCLFSGLSYAIMQLLGVKIGFTFSGGLIDFLLFGVLPNRTPWYLAILVGIGFAVLYY
                     SVFRFMIRKFNLKTPGREDESETNAEVIEMSKNELASEILIALGNKDNLKSLDACITR
                     LRLVVNDINKVDKEKLKSLGAAGVMVIGNNVQAIFGPKSDSIKSDIKDIIEGKTKVES
                     TVTKNVDKNKVKKNMEVANMENALVEKIDSLTNGEILDIEEVPDSVFSSKLMGDGFAI
                     KSSDGLIYSPVDGTIGVIFPTKHAIIIKSQKSGVEILIHLGIETVNLEGNGFEVFVNV
                     GDEVKAGEKLVKMDLEYIEKNGLSTISPVVFTNLEQNQKLSIKKGVSTAKEENRVSIL
                     RDDIEKIG"
     gene            complement(27771..28640)
                     /locus_tag="KR294_000444"
     CDS             complement(27771..28640)
                     /locus_tag="KR294_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH0238561.1"
                     /translation="MDNKIGYLNDNFKIFNIRDKKDIQFEYHNHDFNKIIIFINGNVT
                     YFVDGIPYKLKPWDILFISNNEIHKPVIDSNVFYERIAIWISPEFMKKNSDASSDLEK
                     CFKIATENKCNRLRLNIHDIESIKSFIEQINISESNTEFGNEILRNALFIQLMIFLNR
                     IFLKNENMESTEDVFYDETIKKVLNYINSNIDDKLSIDSISSEFFISKYYLMRKFKSH
                     TGTSIHNYIVQKRLILAKSLITNGHLMSEVCNKCGFNDYSSFVRAFKKNYGVSPKNYI
                     NNKNPLDITLLDE"
     gene            28804..30258
                     /locus_tag="KR294_000445"
     CDS             28804..30258
                     /locus_tag="KR294_000445"
                     /EC_number="6.3.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HBH0238562.1"
                     /translation="MKLNDIIQGLDIINIKGELNIDINNVQYDSRKVTKGTLFICIKG
                     FVSDGHKYIKDAIEKGASAFLVEEDVEIKGCTFIKVKDTRKDMAKVADNFYNHPSQKF
                     NVIGVTGTNGKTSITTILNEILTLNKNKVGLIGTIKIFDGEKDIVSNSTTPESIDLQY
                     HFNNMLDNGCDYCAMEVSSHSLALNRVDETDFKLGIFTNLTPDHLDFHKDLEDYRKAK
                     EKLFFKTTMANIINIDDEGGKKIYENIKGINVPCYTYGVDTKADFMARDIKSDSDGVS
                     YRLITPSYEEVIFIPVPGMFTVYNTLAVIAACYVLGIPKPIYKEGLRLSNGVSGRFET
                     VPNDKGISVIVDYAHTPDALENVLKTTQQFAEGKIISVFGCGGDRDTEKRPLMGAIGQ
                     KYSDLCIITSDNPRTEEPEAIIKDILEGIDKKKENYHVVVDREQAIAEAISMAKKDDV
                     VIITGKGHETYQIIGKVKHHFDDKEVANECLSKM"
     gene            30529..32808
                     /locus_tag="KR294_000446"
     CDS             30529..32808
                     /locus_tag="KR294_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBH0238563.1"
                     /translation="MLSDAKNNRYGLSIIAVISILVITISCLIYGSRLNKTLGEETNQ
                     YLSEIANQSVNVLKKQINGDIKLLESISIFIEGEESFEVDNILSILKRQAINSSFKRM
                     GVILPNGTAYTTDGYIEDFSKRDYFLKSMQGEVVITGKLKDVIEDDKNTNSNINVYSV
                     PIYKDNEVKGVIFATHSTKLYEKILSVPTFNGKGYSYITRSNGDIVLNPSSKNANSTK
                     ENLFSYIGRSDSISKSSINNMKSNIKNFKSGSLSYSMFGKGYYLSYAPIGINDWYLFS
                     EVPKTAISEKSYAIIKLTLSACVVLIIIFTALTIYILFIHKKSKEKLEEFAFKDNVTG
                     IGNSNKFNLEGGKFLSSHEKKNLVLIYFDIDKFKLVNDRFGYEEGDRVLKEIAEIIKN
                     IFKEQSVFSRISNDNFAIIFEKKNNRESIIEICELIRKKLSMIKTSLGVELNLIPSIG
                     VYFVEEGETNISTCLDKAMIAKTTVKRKYLKVYEIYAENLKETLIEERDIEQEMHDAL
                     KNEQFKVYLQPKVDLSTTKIVGAEALVRWQHPKKGLISPGVFIPIFEKNGFITELDMF
                     VFTQVCKNFKRWENENFPTFPISINLSRVHLENPGFISELERITKEYEIEPNLIEIEL
                     TESAIFDNTKILFKIMQTLKSVGFKISMDDFGSGYSSLNMLKDMPIDVLKLDRQFFIT
                     VGNAKKSQIVVSSIVQMAKQLDIKVVSEGVETVEQAEFLRFIGCDMAQGFLFARPMPI
                     EEYEKLILDRYSLNRKETN"
     gene            complement(33287..34384)
                     /gene="ychF"
                     /locus_tag="KR294_000447"
     CDS             complement(33287..34384)
                     /gene="ychF"
                     /locus_tag="KR294_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HBH0238564.1"
                     /translation="MKLGIVGLPNVGKSTLFNAITQAGAESANYPFCTIDPNVGVVSV
                     PDERLNKLQELYNSEKIVPTAIEFCDIAGLVRGASKGEGLGNKFLSHIREVDAIVHVV
                     RCFEDENVVHVDGSVDPLRDIETINLELIFSDIEILERRINKTQKAAKADKTLGSELD
                     LLKSIMSTLEESKCVRTMEFTEDEQTFVNSLDLLTSKPVIYASNVSEDDLADNGENNK
                     YVQQVKAFAETEDAEVVVVCAQIEAEISELDSAEEKKEFLETLGLEQSGLDKLIKSSY
                     ALLGLISFLTAGPKEVRAWTIKVGSKAPQAGGKIHSDIERGFIRAETIAFNDLVEHGT
                     MAAAKEKGLVKLEGKEYIVKDGDVILFRFNV"
     gene            34700..35965
                     /locus_tag="KR294_000448"
     CDS             34700..35965
                     /locus_tag="KR294_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HBH0238565.1"
                     /translation="MVNTKKIINLGNNINLTLIKTEKFKSNLISLYVQRLLDEKETTK
                     NALIPSIIASGSSKYPSARAISNKLDDLYGSSMGADAVKRGERQVLSFKVINISEKYL
                     DESIFEEVVEFFNEVINNTLVVDGGFKEEYLNIEKENLREKIQSIINDKKEYAQDKCI
                     EAMCKGERYSVSEFGYEDEIDSITSRELYEHYKNILKTSPIDIVVEGNFDEDKVVDII
                     SKNLKFEREEIINIPRADFIKNVDEVKVIDEQMEITQGKLVMGYRANVDYADIDKYYA
                     LVVGSNVLGGGPHSKLFVNVREKESLCYYIFSSIEKYKSIMFISSGIETKDYDKAVEL
                     IKKQVESVKAGDISDEELENSKLALVNSMKSITDNIGGMSDFVFSQSMAKTNSEVQDI
                     ISSIEKVTKKDIVEAIKNIELDTVYFLRN"
     gene            35980..37266
                     /locus_tag="KR294_000449"
     CDS             35980..37266
                     /locus_tag="KR294_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HBH0238566.1"
                     /translation="MEKIVNDILKEEVYYEKLQNGLDVYFMPKRGFMKKYAILATNYG
                     SNDLEFVPIGEDKKIRVNEGIAHFLEHKMFEQPDGGDAFDKFSKLGVNANAFTNFTMT
                     AYLFSATENFYESLEHLIDYVQTPYFTDENVEKEKGIIAQEIKMYNDDPDWNVYFNCL
                     KAMYVNYPARIDIAGTVDSIYKITKEELYKCYNTFYNPGNMALFVVGDLDVEKVIDVT
                     KKSNNYKVDKLSKSIERFYPEEPEGVKEKEVIEKFPISMPMFNIGFKDSNVGLKGKEL
                     LRKEIVTDILVGMLFKKGSKLYEDLYMQGLINENFGAGFSSQVDYAFSIIAGDSKEPK
                     KVKEIILDYIEKSKKEGLSKEEFERTKKKKIGSFIKCFDSINFIGNSFISYVFKDINL
                     LEYLDVIKDITFEEVEERLKEHFKEEYCVISIVEPK"
     gene            37660..38406
                     /locus_tag="KR294_000450"
     CDS             37660..38406
                     /locus_tag="KR294_000450"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HBH0238567.1"
                     /translation="MDRVAFTLFGIDIMWYGILMACGMILGTLIAIKEAKRVGIKEDD
                     VLNIAIIAIPVGLICARIYYVVFNWSYYAQNMSQIFNFRGGGLAIHGGLIGGILAGYI
                     YTKIKNINFLKMADTVILGMPLAQAIGRWGNFINGEAHGGATNLPWGIMVDGVKVHPT
                     FLYESIWDFGIFIVLLLFRKNKKYEGQVIVTYITLYSIGRFFIEGLRTDSLMLGPLRM
                     AQVISLIGVIGGIIAHVYLSKKNKNNISEE"
     gene            38436..39371
                     /gene="rsmH"
                     /locus_tag="KR294_000451"
     CDS             38436..39371
                     /gene="rsmH"
                     /locus_tag="KR294_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HBH0238568.1"
                     /translation="MEFHHVSVLLNECIENLNIKPDGVYVDCTMGGAGHSKEIVKKLS
                     DKGLFIGFDQDKNAISTAKERLSEYESRVKFVHSNFENIKEELEKIGVYKIDGVLADL
                     GVSSHQLDEADRGFSYMQDAPLDMRMDVRCEFSAYDVVNTYTEDELTKIIKDYGEDNW
                     AKRIAKFIVEERANKPIETTGELVDVIKKAIPKKARIDGPHPAKRTFQAIRIEVNNEL
                     GVITKMINDASSIMNEGGRICIITFHSLEDRIVKNAFKHLASDCICPQHLPICQCDKE
                     SEVKIITRKPILPSEEEIEVNPRSRSAKLRVAEKI"
     gene            39857..40204
                     /locus_tag="KR294_000452"
     CDS             39857..40204
                     /locus_tag="KR294_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0238569.1"
                     /translation="MKKNYKIHNLNEYKNKKKNNYKKRNKKKIGAKCILLIATFSVII
                     LNLCGYSKISEMKYDIYYLQKDLRKKEIVLEELKAKETEKTSIKEIELKAKELLNMDY
                     PKDGQIKYIDVDN"
     gene            40216..42195
                     /locus_tag="KR294_000453"
     CDS             40216..42195
                     /locus_tag="KR294_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein D"
                     /protein_id="HBH0238570.1"
                     /translation="MRKVKRISKKRLVLVLILACALFFCLVIRTGYLQLMKGNWLSTK
                     ALEQQTRDIPIEPKRGTIYDRNMKELAVSVTKYTVWCKPVEVEDKKEAAEKVAEILDE
                     DYKDIYALISKKNMALVKVKRWIDDDKASQIRDAKLSGIWVAEDNQRYYPYGNFAPYV
                     LGHTSSDATGISGVEMQYDKKLKGKPGKLIVSTDASGREIPQGMEKYYEPVQGNGLVL
                     SIDEVIQHYTEKAVQKAYELNNAKKVTAIAMNPKTGDILALASKPDYDPNDSRTPIYP
                     YYQEELEKYNDKDKIKGYYQMWRNPAVSDTYEPGSTFKLITSSSALEEGVIKDGEKFT
                     CTGSVTVGGRKIKCWRHYRPHGTQEFKQAVQNSCNPVFVELGSRLGVGKMYDYIESFG
                     LMDKTGIDLPGEAKGILYNEKNVGPVELATISFGQSISVTPIQLITAISSIANGGDLM
                     QPRVVKSYTDNKGNITETVKPKKVRSVISKETSKKMLEIAESVVTEGGGKIAYIPGYR
                     LGGKTGTAQKVIDGKYAPGKYICSFVGIAPCDDPQIVVLAIVDEPTGVSAFGSTTAGP
                     IVKEIMNDSLKYLGVKPVYKEEEKAEYEKKQVKVPDVRNLKIGDAVKALEDAKLKPDL
                     DADIELPEDTKVKDIFPKPGVKVNEDSSITLYFEN"
     gene            42362..43735
                     /locus_tag="KR294_000454"
     CDS             42362..43735
                     /locus_tag="KR294_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HBH0238571.1"
                     /translation="MECLTIKELVLATNGKLIYGDYNDCVSDIVIDSREANAQNAFVA
                     IVGENLDGHTFMKSAYDSGCKTFIKNESNGIKLESSDINLIEVKDTSLALGDISKYYK
                     EKFDIPFIGVTGSVGKTTTRDMIYSAISAKLNILKNEKNLNNHFGVPLTLFNLNKEHE
                     CAVIEMGMSGFNEIKYLVDIVNPKIAVISNIGLSHVEKLGSQEGILKAKMEITSNFDE
                     TNTLIVNGDDKFLSTLKEKEHVYKLKTFGFNKNNDVYCESYTMEEDSLTFICVINGKK
                     EEIFIPTIGEHNIYNAMSAILVGLCLNISLDYIKKGLKNFKGTKMRLDIIKNEKLTII
                     NDSYNASPDSMDAALKILGRYKGRRVAILGDILEMGEISEYGHRLVGKSSMNNTDIII
                     TIGENSVFIGEEAKQLGFNSANIYHFENREDVFNKLNELVKTGDTILVKGSRGMRLEK
                     IVEYLNK"
     gene            43776..44744
                     /locus_tag="KR294_000455"
     CDS             43776..44744
                     /locus_tag="KR294_000455"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HBH0238572.1"
                     /translation="MMLGITELTYTALIAFLIVIIIGPIFIPMLRKFKFGQTVRDDGP
                     QTHLAKNGTPTMGGIIMIVAILITGLTRVKVSHDMAVGLICIAGFGFIGFLDDFIKIK
                     LKRSLGLKAYQKIILQVALSFYVAFYQYTSSSSASQLMIPFTDFVINVGILYIPIMMF
                     IIVAIVNAVNLTDGLDGLASGVTLIVSVFFMLFASSIAGNTEVAVLAAATVGACLGFL
                     GFNSYPARVFMGDTGSMALGGAVVAFSVLTNSVLIIPIIGGIYFAEALSVLIQVGYFK
                     ATRKRFFKMAPIHHHFEQCGWPETRVVFIFWIITVVLAWISIIAVF"
     gene            44763..46118
                     /locus_tag="KR294_000456"
     CDS             44763..46118
                     /locus_tag="KR294_000456"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HBH0238573.1"
                     /translation="MDLKGKKVLLVGLAKTGISTIKHLDKLGASVIVNDIKDENKLRN
                     ILDELKSINDIKYILGHHPEDVDDIDMVVVSPGVPLDLPFILKLKNSGKYIIGEVELA
                     FKLSNNPIFIGITGTNGKTTTTSLVGEIFSRAKRDTYVVGNIGNPVIDTIETSSEESV
                     LVTELSSFQLESIDEFRPKVSAILNITEDHLNRHHTMEKYIEAKANIFMNQTVEDFCV
                     LNYDDEIVKSLADKCNAKVIYFSRTKKVNGGVYLENNDIIIDIDDKIKFLNKDDVSLP
                     GGHNLENCMAAIAIAYVCKIDLEVIKDVLMTFKGVEHRQEFVRNLDNVIYVNDSKGTN
                     PDSTIKAIQSYDRPIILIAGGMDKGSNFDELLETAKSYVKSLVLLGETASNIENCAKN
                     KGFNDIHIVKDMEEAVKTSYEISKSGDIVLLSPACASWDMYESFEVRGKDFKDNVNNL
                     K"
     gene            46170..47300
                     /gene="spoVE"
                     /locus_tag="KR294_000457"
     CDS             46170..47300
                     /gene="spoVE"
                     /locus_tag="KR294_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein E"
                     /protein_id="HBH0238574.1"
                     /translation="MPKENLKKQIDIRMKTEFDGVVFYTTMLLVFVGIVMVFSASFIQ
                     SSFKHNDAYYFLKKNVIYAVLGFIVMIITSRIDYSFWKKNATAIGAIAVVLLLLVLTP
                     LGIEANGAKRWLGIGALTFQPAEIAKFATIILTAKLIEKNYDKIKSLTKGVVPLLVVP
                     GIFFALIILQPNLSTAGTVILVTFVMIFVAGMDMKIVFAMIGSGAALFAALVIAEPYR
                     LSRVTSFLDPFQDPLGKGYQVIQGLYALGSGGLFGLGLGKSKQKYFYIPEPQNDFIFA
                     IIGEELGLIGCIIVIMLFVVLVYRCVRIALKTSNVFACMVVIGIGAQIGIQAALNIAV
                     ATSSMPATGVALPFISYGGTSLTIFMGAVGIVLNISKHVKIN"
     gene            47318..48544
                     /gene="murG"
                     /locus_tag="KR294_000458"
     CDS             47318..48544
                     /gene="murG"
                     /locus_tag="KR294_000458"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HBH0238575.1"
                     /translation="MKVLLSGGGTGGHVYPAIAIANKIRDEHPDAEIIFVGTEKGIES
                     EIVPKYGFELKTVTVQGFKRKIDFDNVKRVFKLFKGLEQSRKIVKKFKPDIVIGTGGY
                     VSGPVLFNASMGKIPAIIHEQNSFPGVTNKILSKTVTKVLTSFEDSHKRFPEAAEDKL
                     VFTGNPVRKEILLSRKNIARKNLSISDEKRMVLCYGGSGGSRKINDAMRLVIKNMVNE
                     DIAFIFATGKSYYDEFMGSISDINLKPYQKVVPYLEDMANALAASDLVIGSAGAISLA
                     EITALGKPSIIIPKAYTAENHQEYNAKSIEKQGAGIAILEKNLTPESLNTAVFKLLGD
                     RELLVDMANASKTIGKPEAIDLIYDEIMKVYNSTQKSTSKKTKKEKVIKEVKEIKKET
                     TPSIEGQAKVIGIKKR"
     gene            48814..49554
                     /locus_tag="KR294_000459"
     CDS             48814..49554
                     /locus_tag="KR294_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsQ-type POTRA domain-containing protein"
                     /protein_id="HBH0238576.1"
                     /translation="MKKRRKLNTNNVMIVLVFILMLSFCICIIVKSDLFDVKKIDVIG
                     NKRVTKSNIMKELNVNLNENIFAYNFKDMKNKLIKNPYIENVEIKRKLPNKIIISLKE
                     KEIFAVLKDEDNYCYIDKKGNLLEELRGSNESKKDLIVDVDYSIDDNKSIKFKNYKTK
                     ENVFKTLNYLKEEGIYRKINYVNLKKESNIEMLTRSNIKILLSNDDNLDYNISRVSKI
                     LIDLQNKNTNGGTINLNYGKLAVYSPEG"
     gene            49577..50275
                     /locus_tag="KR294_000460"
     CDS             49577..50275
                     /locus_tag="KR294_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF881 domain-containing protein"
                     /protein_id="HBH0238577.1"
                     /translation="MKKRFINKSIIIGSIVLGVLVSLQLKIINIENRGMTTFKRGEQL
                     TEELKSLKKEKENLQSEVNSVKKDIEIYRGKNNEGEQDILKSEIEKYETLAGYTDVEG
                     TGIKIEINSTKDLGNSDKNDSILYNYDLLLSMINKLNSAQASAISINDQRIVSNTYMY
                     LKEDKLYMNDTVIKEPIIIKAIGDSDTLASALNIKYGIVWEIETYYNAKVKVTKEDNI
                     EINGHSDINKAEGK"
     gene            50280..50954
                     /locus_tag="KR294_000461"
     CDS             50280..50954
                     /locus_tag="KR294_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF881 domain-containing protein"
                     /protein_id="HBH0238578.1"
                     /translation="MKKKIVILGAFILGVFISTYIKSLDPNRVYITLGQTESIESEVE
                     NTKKEIKNLKETLKKNKKTLNEYKEAKKNGNESIQTLMQKELEEVKELSGYSTVTGPG
                     ITITMRDSERELKDGQNPNDLIIHDIDILRVLNDLKKAGARAISINGERVLATSKIKC
                     SGATITVNDTTYGQPFIIKAIGDIDLLSAAINSPESYAKSLKDIYGINIKVQENNGNK
                     VNLFAK"
     gene            51053..51406
                     /locus_tag="KR294_000462"
     CDS             51053..51406
                     /locus_tag="KR294_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small basic family protein"
                     /protein_id="HBH0238579.1"
                     /translation="MLWVLGGLAFGVVVGYYIPFTYSMDYSIYMSVAILAIMDSIFGA
                     IKSNFEDNYDNVIFITGFIGNAILAILLTYIGEKLGVSLYYVAVLVFGMRLFNNLSII
                     RRYIISNIMNKKRKN"
     gene            51596..52753
                     /gene="ftsZ"
                     /locus_tag="KR294_000463"
     CDS             51596..52753
                     /gene="ftsZ"
                     /locus_tag="KR294_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HBH0238580.1"
                     /translation="MLNFDVELEECAQIKVIGVGGGGNNAVNRMVEAQLKGVEFISVN
                     TDKQALYTSKAEYKVQIGEKLTRGLGAGANPEVGKRAAEESKDEIVKLLQGADMVFVT
                     AGMGGGTGTGAAPVVAGLAKEMGILTVGVVTKPFAFEGKIRMKNAEGGIAELKSKVDT
                     LITIPNDRLLQIVQKNTSMLDAFAVADDVLKQGIQSISDLIAVEGLINLDFADVTTIM
                     KDKGLAHMGIGSASGETRAIDAARQAIQSPLLETSIQGAKGVLLNVTGGPNLGLFEVN
                     EASTLVMESCDPEANVIFGASIKEDLGDEIMITVIATGFEGLQNGALDLDTKPKSSIR
                     SSLNTTVKQAVKEIEEEVIAEEKIEPPKKASIIEEDDDESMEIPTFLRRRR"
     gene            53037..54311
                     /locus_tag="KR294_000464"
     CDS             53037..54311
                     /locus_tag="KR294_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HBH0238581.1"
                     /translation="MIKLKKVLSLVMVGILSVSILAGCSKKEDSKGKEGKEKLVVWSA
                     PLTDHDADAWKPIFEKFEKENNCEIEFQIVPWDNYAEKYATAISAGEGPDIGYMYAEM
                     FPQFIEMGAVEDLTPYLEKSGTSDNYLYLDDAKMMGGIYGLPIEAANPGVLYYNKDIL
                     EKLGEKPPKTWDDFKRICEKATKDTDGDGKIDQWGLAQGWGSKVFGSLNWNWYPYLWQ
                     AGGDIYNDDLKSVKFNNAEGLKAANFINDMKKYIPEDALSKDSNEMIESVFGPGKAAF
                     TIMLSSAATSTFDKSFPDLNWGYVTSLEDKTVGSFASVDDLTLMSACKNKELGFKLLE
                     YMLSKESMEAFHKEIPRAPVAKGEKYQGDPRFEEMVTRDKHMYRPLTVGPHGVEIYEY
                     LWKQLQMMIAGDITPEQALNESAKYANGLLAQ"
     gene            54601..55473
                     /locus_tag="KR294_000465"
     CDS             54601..55473
                     /locus_tag="KR294_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-E processing peptidase SpoIIGA"
                     /protein_id="HBH0238582.1"
                     /translation="MFKGFKGGYMVYIEYYVIENLVINYIIISCTSILTKRYNPKKNK
                     LLGASLGGAYSVAYLYPSMNILFTVPFKIIIMSIITLISFRSKSKKDYVHVALVFYLV
                     NIFISGSTYFIIYFTGISHLKISFLIACTYVSCELLKYIYKDLKMLKYIKELTKTINI
                     NLLEKSFCCKALVDSGNLLKDPISQSDVIIVKSSVLEGFIPEKLLNINYEDIDMKKAQ
                     EIIGSLDDKTSGRVRIIPYKHAGSNKTSIIIGLKADYIEVDEQKIGNIILGISNFNDR
                     EYGAIMNPNILPGF"
     gene            55498..56220
                     /gene="sigE"
                     /locus_tag="KR294_000466"
     CDS             55498..56220
                     /gene="sigE"
                     /locus_tag="KR294_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigE"
                     /protein_id="HBH0238583.1"
                     /translation="MLRLKERIISFITMLGIKLKIIKPKGIYYMGGANILPPPLKPEE
                     EMELLQKLETDESVKSILIERNLRLVVYISRKFENTGIDVEDLISIGTIGLIKAVNTF
                     KLNKNIKLATYASRCIENEILMYLRKNNKKKTEVSFDEPLNIDLDGNELLLSDVLGTE
                     NDEIYKIIEEEIDRDLLVMALDRLSDREKQIMELRFGLIDKGIEKTQKEVAGMLGISQ
                     SYISRLEKKIISRLQKEMKKFV"
     gene            56312..57085
                     /gene="sigG"
                     /locus_tag="KR294_000467"
     CDS             56312..57085
                     /gene="sigG"
                     /locus_tag="KR294_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigG"
                     /protein_id="HBH0238584.1"
                     /translation="MQVNKVEICGVNTSELPVLKNKQMKELLLQIKNGDEEARQQFVR
                     GNLRLVLSVIKKFNNRGENIDDLFQIGCIGLIKAIDNFDLSQNVRFSTYAVPMIIGEI
                     RRYLRDNNPIRVSRSLKDIAYKALQVRERLIRTNSKEPTVSEIAKELELEVESVVMAL
                     DAIQDPISLFDPVYQDNGDAIFVMDQVQDKKDTDENWLQEISLKEAIKKLNSREKLVL
                     DLRFYKGRTQIEVADEIGISQAQVSRIEKNALKNMRKYV"
     gene            57189..57452
                     /locus_tag="KR294_000468"
     CDS             57189..57452
                     /locus_tag="KR294_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlmC/YmxH family sporulation protein"
                     /protein_id="HBH0238585.1"
                     /translation="MIRVSDIMEKEIINVKNGKRMGFIIDIDMDIHEGKVVSFTIFGD
                     GSRSFFSRGGDEEVIFWNDILKIGCDTIIVNIGSELSLDEFEI"
     gene            57474..57935
                     /gene="nrdR"
                     /locus_tag="KR294_000469"
     CDS             57474..57935
                     /gene="nrdR"
                     /locus_tag="KR294_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HBH0238586.1"
                     /translation="MQCPYCNYKESKVIDSRHTDLKSIRRRRECESCKKRFTTYEKIE
                     TTPLMVIKKDNSREYFDREKIKYGLLKACEKRPVSIDEIESIVVHIENEINKCFIEEI
                     ETKKIGEMVMDKLKELDEVAYVRFASVYRQFKDINTFVNELKSILIEKGDK"
     gene            57932..58693
                     /gene="pgeF"
                     /locus_tag="KR294_000470"
     CDS             57932..58693
                     /gene="pgeF"
                     /locus_tag="KR294_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan editing factor PgeF"
                     /protein_id="HBH0238587.1"
                     /translation="MMKDYINIKNVQDIKEYVNLSGNCEELDEKLNSVNLVITCKNID
                     AKNREDMLKVCKECDLTFENLTSNSQIHSDIVNIVNKDTIGKRRDGDALITNLEKVPL
                     LLFTADCVPISIIDAKNKAIGLAHAGWRGTFSNIGHKTIKLMSECYKTVPEDLVCIIG
                     PSIGPCCYEVSEDLVEKFNTILTNNDEKFYIIKEGSYYLDLWKINEYMLRCSGVKKEN
                     IINLNLCTSCRADKFHSYRKHNKASERIGTVLQIK"
     gene            58708..59400
                     /locus_tag="KR294_000471"
     CDS             58708..59400
                     /locus_tag="KR294_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0238588.1"
                     /translation="MNTKVLVIDDEMHIVELLKFNLEVSNYEVSYSYDGFDGFIKAKE
                     IKPDLILLDWMLPNISGIEVLRKIRSDKDLKNIPVIMLTAKNMENDKVEGLEIGADDY
                     ITKPFSIKELLARISSVLRRYNLTSLGEENNILTTGNLKLDLSKHEVTKGSEKIELTL
                     KEFELLKLLIQNKGKVLSRNYLLDKIWGYEYYGETRTVDVHIRYLRKKIEDEDKSEKY
                     IETIRGVGYKID"
     gene            59429..60718
                     /locus_tag="KR294_000472"
     CDS             59429..60718
                     /locus_tag="KR294_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH0238589.1"
                     /translation="MEDLNSIYFFIVMLSIAIVILAVRYTITLRKYLKEFIYVSKKVS
                     NNEYHARLNISAKGELGELARNFNHMIKNMDKTLEEVQYKHLQLRSILKSISHGILAI
                     DVNGNILLINDEAKEMIKSEPNQLVEGHNINVVIKEEEILKQILQFIGSKDNETANIT
                     TKDDIVYKIKVDPVYLQNTNNVIIGSIVNIEDITKKVKLENMRSDFVANVSHELKTPL
                     TSISGFVETLKSNENIDVNTRNRFLEIIESESDRLKRLIDDILLLSFVENKDTLLMEN
                     VVVYDVFKEVYEITQHSASEKNIEVLYKCDDKSISILSNKDYIKQVFLNLVDNAIKYT
                     QDNGIVQVVVLKDEEKIVIKVIDNGVGIPKEDVERIFERFYRVDKARSRDVGGTGLGL
                     AITKHIVKSLNGCIKVKSELGIGSEFIVTILQKNFLK"
     gene            60773..61705
                     /locus_tag="KR294_000473"
     CDS             60773..61705
                     /locus_tag="KR294_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YIEGIA family protein"
                     /protein_id="HBH0238590.1"
                     /translation="MEESLLNANLFRHSFIVALVVGILCRGLVLRVTDKQYPSRPQDY
                     LEQIIISGLSASLGAIALPALIDKEFAALTFFAVAIQQFQGLAEQERITLKNIDNEEL
                     VPKGDAYVEEIASTYESRSYISLFSALVSSIVYIVFARKYGLSFFYCTILAIVSGAIV
                     GLIFRRFLRRNSIADIADIVPAKISFEGPILMVNGVIITNIGLESTREKYRNECLAIE
                     VIPRDLGAFGIVNDIGQRQAIIHNLFIHMGIDRDVDEVDIVAISKTNLEKSTVVIPYM
                     PILKDIDVMIDVVKSTPIIETSKGKQSDFSRKTL"
     gene            61750..62682
                     /locus_tag="KR294_000474"
     CDS             61750..62682
                     /locus_tag="KR294_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YIEGIA family protein"
                     /protein_id="HBH0238591.1"
                     /translation="MDRVFFVAVIIGITSRIIMLNLDQKQYPTQPNVLLSQLILAFVA
                     SSLGALLVPALINRSYTSITFLSLAAEQFRQVRANRRNTLQNLEEVQLVKRGAAFIEE
                     IARTYEVRNYMCIVTSFLTIGLYYVILAETKISEGMSLVISSICGLVLAFILKKLLTR
                     KSIGDIADVMPAEISFVDESILKVGDLKGITNIGLKSDREVYINRGVGIQIIPKNKDY
                     ANAGILFDSGQRQAIVYNIYSRLGLYGDYGEPSFVPLPRRNKEDESIMIAYLPVDKNV
                     EKVMEAVKSCPILSSSKGKNLSLKNYKIGKKGSA"
     gene            62684..62884
                     /locus_tag="KR294_000475"
     CDS             62684..62884
                     /locus_tag="KR294_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0238592.1"
                     /translation="MGMDIGLNEYTLAIVTLDKNMKNGGGCPIFYANDEKDLQNKALL
                     MSKCVGGMVHDMTNGTLIIVKH"
     gene            63122..64450
                     /locus_tag="KR294_000476"
     CDS             63122..64450
                     /locus_tag="KR294_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF512 domain-containing protein"
                     /protein_id="HBH0238593.1"
                     /translation="MEVNVKKVNNIISKVYKDSIAEEIGIEVGDLLISVNEQPIHDII
                     EYRFLLSDEYLDVEIQKKDGEVYIYEIEKDYDEDLGVEFTNPIIDQAKSCRNKCMFCF
                     IDQLPEGMRETLYFKDDDSRLSFLQGNFVTLTNMSEEDINNIIKYRISPINISVHTTN
                     PELRQKMISNKFAGKLYGIMKRLADTHIEMNCQIVLCPGINDGKELDRTIKELAQLYP
                     YVNSVAIVPVGITKHRENLVELNIFNDKSASKTIEQIHQIQQKYLEKLGTRFAFLSDE
                     FYILSNSELPGYEEYEGFLQFEDGVGMIRKLKTEIEEYLNILPEKILKREKKVSIATG
                     HSAYEFIQSMADAMMDKFKNLQVNVYEIKNKFFGETITVSGLLTAKDLKEQLEDKELG
                     EALYITRSMLKADEEIFLDNIELNQLEELMRIKIIPCLNEGKDFVDKILK"
     gene            64484..65803
                     /gene="der"
                     /locus_tag="KR294_000477"
     CDS             64484..65803
                     /gene="der"
                     /locus_tag="KR294_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012063975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HBH0238594.1"
                     /translation="MSRPVVAVVGRPNVGKSTIFNKFAGKRISIVENTPGVTRDRIFA
                     EVEWLDKYFTLVDTGGIEPDSEDIILSQMRNQAMLAMDMSHVILFIVDGKAGITAADK
                     EIAQLLRKTKKPVILVVNKIDSQSQFDNIYDFYELGFGTPFAVSGANSMGFGDLLDEI
                     VENFPAGLDTEYEEDIIRVAITGKPNAGKSSILNKILGEERVIVSPIAGTTRDAIDTY
                     FEKNGQKFLLIDTAGLRRKSKIYETIEKYSVIRAMSAVDRADVVLIVIDALEGVTEQD
                     TKVAGIAHDEGKGCIFVINKWDLIEKDNKTMSNYTKDIKEKFPFMMYAPIVFVSAKTN
                     QRMNKILDTVEYVSNEHSKRISTSALNEVIGEAVMLNQPPSDKGRRLKIYYGTQTDIR
                     PPKITLFINDKDLTHFSYQRYLENKIRENFGFEGTSIKFEYRQKNKK"
     gene            65838..66452
                     /gene="plsY"
                     /locus_tag="KR294_000478"
     CDS             65838..66452
                     /gene="plsY"
                     /locus_tag="KR294_000478"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HBH0238595.1"
                     /translation="MEIFSYIIIAVVAYLLGNISTSYIVAKRIAGVDIRTQGSGNAGS
                     TNVLRTLGKRAGAMTFLGDVLKGVMAVLISEFAARLVGIDTLLAGYLAVICVVAGHNW
                     PAVLGFRGGKGVATSLGAMLAVNPVITLMCLAVFILVVAITKYVSLGSVVGIGCSPIF
                     MIMVKNKAGLIVALFLTASVIYNHRANIKRLLNGTERKIGQKKE"
     gene            66483..67502
                     /locus_tag="KR294_000479"
     CDS             66483..67502
                     /locus_tag="KR294_000479"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HBH0238596.1"
                     /translation="MEKVCVLGTGSWGSALALGLAKKGNDVSMWTRKEEQAKKINRTK
                     ENTDYLPGVLFPNNITISTDIEKTIKDCKVIVLAVPSQAVRSTCQKIKPFIKEGQVIV
                     NVAKGLEKGTGLRLSQVCEEELPQNPYVILSGPSHAEEVARDIPTTVVVASKDLKIAQ
                     MIQDLFMSPKLRVYTNPDIVGVELGGALKNIIAFGAGICDGLGYGDNAKAALMTRGIS
                     EMSRLGIAMGANMSTFAGLSGIGDLIVTCTSMHSRNRRAGILIGKGMSLEDTLKEVKM
                     VVEGITATEVAHDVAEKLDIDMPITNAIYSVIKKGSNPKEVGIELMMRSKKHEMEEVV
                     LGDDI"
     gene            complement(67659..68309)
                     /locus_tag="KR294_000480"
     CDS             complement(67659..68309)
                     /locus_tag="KR294_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH0238597.1"
                     /translation="MTNKELQKKRILMYFIEAAQNIMENEGIENITLRKVADMAGYNS
                     STLYKYFKNLDHLISFASIKYFKDYNLNISRCIENVNDEYKKYIIMWKLFCKHSFDNA
                     QAFYQVFFNLSSDELSYITKQYYDMFPEDLGIHDSDISLMITGESIKERNKILLNNLV
                     DTGYIPAKDLDIINDIIISFYQNLLFLKKNTGKNSDDDELTMKMISSIEYIIKHAK"
     gene            68628..69767
                     /locus_tag="KR294_000481"
     CDS             68628..69767
                     /locus_tag="KR294_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBH0238598.1"
                     /translation="MSNNMRLERLRKYMNEKSIEIALIFEPDNQFYISGFKAITYSRP
                     IVTVVTQDKIELIVPGLEELHAKEVAKVDNVYVYYEIPEMKEHGISHKHYLDIILNKY
                     PKGTTVGIEKDIVSASFSEYITDKSFAIKDVGSKIFEMRYVKDAKEIEFLKIAGYLSD
                     IGIKGSLENVRVGMSELEFDVEGDNALLKYVSENYPDTYIGFANWTCSGIDRTAQPHL
                     DSNTRILQRGDIVIHSRQVWYENYRAENERTFIIGKPTERQKEVFKIAVEAQQAGLDT
                     IKAGIPARMVDEAARAVVAKYGLELYSNHRIGHGLGLSEHEEPYLRFDNELILEEGMV
                     FSMEPGIYIPGVGGFRHSDTAIVGKNGATIITNYPRSVEELILDI"
     gene            69819..71228
                     /locus_tag="KR294_000482"
     CDS             69819..71228
                     /locus_tag="KR294_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBH0238599.1"
                     /translation="MKKKIGFWDLVFMNISALFGIRWIAKSTASSFGLGLGSIPVWLL
                     FAFIFFVPASLICAELAATYPKDGGLGEWVKQAYGEKWGFMVSWLNWTSKIFWYSSFL
                     TFLAINIAYMLGNPDLSNNKMFILALSLIIFWLLSLVSTRGMAFGKFFTNTGALGSTI
                     PAILLIVMAFMSVVILKKAPSASIYTIQNIIPKIDANSLVSISAIIFALSGAETTANF
                     ITEMDNAKKNFPKAILTVAVLIGGIYILGSVAITMILPPDKIAASTGILDALAKVAQD
                     LGIGSWFIRIVAFGITLSVLGALILYIAGPVKMLFGNVREGVFPKQLTVTNKYNIPSN
                     AVIVQAIIVSLLLVGTNLLPSVDNIYNVLVTMTALTALFPYVLLFTSYIRLRKTRPNE
                     ERPYSIAKSDSVCINIARMVLVVTVVGILFSTAPVMETLKDNIIYEIEMIGGGLFVII
                     TGLMLWKNYEKKISNNSGR"
     gene            71412..72707
                     /locus_tag="KR294_000483"
     CDS             71412..72707
                     /locus_tag="KR294_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH0238600.1"
                     /translation="MSVEVNKPSIWKNFKVLIILFVAGAFIYALPYLKNYYYDTFAQA
                     FNLTNTQMGSLGSIYGLLAMVSYLFGGFLADRISARKLLSGSLIITGISGLVLTLYPP
                     YIVVFLIHALWGITTILTFWPALVKAVRMLASENEQGKAFGFMESGRGITNAIHLSLV
                     LILFGYISSKVSDKSGLTAIIVLYSAINVIVGVLVFFKLKDNEKEVSAKFDKEAFFAV
                     IKMPHTWIITIIMFCSYSANMSFYYFTPYSTEAFGATVVFASAISILAQYCRPVASAA
                     SGLLGDKVGSSKIISYGFILMIAGLLGVIFTPTKSSMIYILLIGCVAIYVSMYAIQGL
                     HYSLLEEGNYSLSISGTAIGIVATLGYLPEVLCPLAAGKILDAFPGVTGYRYYFIVLT
                     IVAIIGLVFTFIWMNMTKERRKELIEMNNNSNENTTKVS"
     gene            72879..74354
                     /gene="spoIVA"
                     /locus_tag="KR294_000484"
     CDS             72879..74354
                     /gene="spoIVA"
                     /locus_tag="KR294_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage IV sporulation protein A"
                     /protein_id="HBH0238601.1"
                     /translation="MNNNIYEDISKRTQGDIYIGVVGPVRTGKSTFIRKFMEKLVIPN
                     IDNEFKKDRTRDEIPQSGSGKTIMTVEPKFVPADGVEIKIKDTVSLKVRMVDCVGYIV
                     EGALGHEEGGKQRLVSTPWSQEAMTFEKAAEIGTKKVIKDHSTIGIVVLTDGSVTGID
                     RKSYVEPEERVIQELKNLKKPFAVVLNTLSPKSEETSMLRSELEEKYEVPVLPMNVVE
                     MEEEDIEEVMEAVLYDFPLTEIRINLPKWVEGLERNHWIKSSIITTLKQSIIDIGKIR
                     DIEGIIQGFSELEFLEDTGVDNVELGEGVINIDLQTKQDLFYNVLEEKSGFKIEGDYQ
                     LLSLITRLSKVKNEYDKIESALIDAKIKGYGVVAPSLEELSLEEPEIMKQGKQYGIKL
                     KANAPSLHIIKADISTEVSPIVGNQNQGEEMIKYLMEVFEEQPADLWESNMFGKSLHD
                     LVKEQLQSKLYTMPEEIRVKMQKTLQKIVNEGSSNIITILL"
     gene            74537..>76402
                     /locus_tag="KR294_000485"
     CDS             74537..>76402
                     /locus_tag="KR294_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0238602.1"
                     /translation="MKKYEIFIFMSIIVLCFISFPHKVFGQEENCLEDFERWVQENKN
                     NKEEIVYTLSCDMVIDEEFRFYIPYDSNFTIDTNKYKILIKNHGRFIIDDNELNIIGE
                     GGKEGVIHIENGGSISIGINNIIATDGTALYVEEGGDLHIKSSYESVEKIKANGKDAI
                     GIYTENDIRILNKDIEVNGEHAIGVYSKGDVEIEETSIKAYSSNNESGLLRDNNKLAQ
                     SIISESKKVYIIDDYNELIPSIAEDSGYDIVKCCHRGIGVFSDEIKVSKDDKIENIKF
                     PKYMVLETSSGNRLDIDVEWDFTDYYEKLEKGENFNITGKFKTEMLNKEKIIINDDVV
                     PILNVSVIEKKPIDNLELEFQNTKNGYVAVLFYDMPYSASKVFVEYSSDGINWISEEQ
                     EDIRDQAILFFEDFKLRCFRVKVVGGLKEGYSNIVFKPGFIMGGGDNQETPDDEREND
                     DIDGDRGGGGRDDPDRDEDDNNQDGNNGNENNDSNNNQNNNNENNNNENDNSDEKQPN
                     TPKDDVESSTDSNENKNPHDIPKDGNKENNSDKEKGFYNKNSITENDDNYDLSSKSVF
                     GTNEHSFPYRESISNKNQDTNKNKSNISDYDGIINNNYKLESKEYNLKKDIIFLFC"
BASE COUNT        29567 a         8696 c        13242 g        24897 t
ORIGIN      
        1 aattattatg cttttgatat ataattatag attctctcat ttccaagttc aatagaccca
       61 gtattaataa gagtaactat tccttctata tctctagcag ttaagtattt atatggaatt
      121 aataaattat aaccagtatt acttagtaag ttttttaatt gggttatttg agagatattg
      181 aaacattttg cagttttagt agattttttt cttaagttag ataaattttc attttgaata
      241 tttattaaag tttctatata gtttctataa gatatcttaa agtttgtctc attgactatt
      301 ttttcattaa gtatactact gataaaatct tgagacaata tattatctgc aaatttatct
      361 gctgttaatt ttccagatgt tatgcctttt tgatattttc taagaatttt tttagtatag
      421 cagtatattt tatttctcgt ttctaaatcg agttgttcta tttgcacaaa accacttcct
      481 tctaattata aaaatattta ttaaaaatct atacttaact aataaagctt caataactta
      541 tttacaataa atactaaatc ataaaatatt tgttattttt tattattacc aagtataaaa
      601 aatattataa ttgtaaaact tacaaatata tgtaaaatat ttaggagtga tgaaaatgtt
      661 aaatgggata ataaagcttt tttattctga aattgtaaaa acaaagatta ataacttaga
      721 ttcaagtgga tattctttaa gagatgaatg taaagaaatc agaaatataa ctctaaagat
      781 agatagtgta ttttttaagc ttttaaagtt agcttttggt tcaatattgc ttatggtagc
      841 ttttaattta aacatggttt taggtatagg agtgttttta gttggtgtag tttatatact
      901 atataaaaga aatatggaag aacaagtaaa agagcatata aataatgtga aaaataatat
      961 cgacatctct aaaataactt ttatggatga aaaagggaga acaggtctaa atgcattaat
     1021 tacattactt cttataggat tattgacagg atttaactgg atattagttg ctagttttgt
     1081 cgttgttttt gtttttacta taaagaatgt atgttaaaat actaataaat agtttaatat
     1141 atagggggag aaattgagta tgactaatgg cagttataaa atgaagaatt tagtggaaat
     1201 atccgctatg gtgactgaat ctacagattt ttttaatata aaagatgaca taatagaaaa
     1261 aatgttagaa gttgttcacc ctacaaaggc atgtgtgaat ctattttata aaaatgattc
     1321 taaatatgcc tacttagtat gttcgcaaac cttagaatat gtacctcaaa tttttccaat
     1381 aaatagtctt aaaggtgcaa aaattgattt tgacacatat ccagagtata tacatgaggc
     1441 tgtaaatgaa aaaaaaataa tatatgtgga aaatgtattt gaagattcta gagcagaagg
     1501 tgaacgagat ttagcaaaag ctgaaggtta tattgggaga atagtttttc cttttataat
     1561 aaataacgta gttgttggat ttatgacttg ttttttaaaa gaggatgatt atataacaga
     1621 acaagatata gattttatat catctgttgc atcactctta agtttatcaa tagaaataac
     1681 taataaaaat aataatgtac aaattttaat tgataaacta agaggctcaa taagtgccat
     1741 aaatgaagct actaaaaaac tataccttaa taagagtatt gatggatttt tggaaaattt
     1801 aagtaaacaa gcgtgtaata ttactaatag taaagaagct ttaataatta taaatagtca
     1861 tcataataag gatgctatag ttagttgtta taatgttgag caaaaaaaga aaacaaattt
     1921 atatcctatg attgatatgt ttttaaagaa agagtcattg ggggggtatt taaataattt
     1981 aaaaccatgc tcaaaaaagg gaataaattt ggaaagttat atatattaca aacttcagga
     2041 taaaaatgag actataggat gtatagtttg tgcaaatagc aaaaactata ctagtgatga
     2101 tttaaatatt cttagtatat tgtccaaaca agtttctgtt ggtatgcaat tatatgaaca
     2161 taatgaaaag gaagtaaaac acaaagttct tgaaaacgag ttgaacatat taaataaaca
     2221 acaacagctt attatggata aaggtaaaat ggattgtaat gatgagaaag aactttattt
     2281 ttaccataaa ccagcaaggg tagtaggtgg agatttttat tatgctacaa aagtggatga
     2341 tgaacatata gtttatattg ttgctgatgt aatgggacat ggaatggtat caaattatgt
     2401 tgttgcaatg ataaaaggtg cttttaaagt attatgcaat caatacaata caccaagaga
     2461 aataatgaca aatttaaata ggatgttata tgatgaattt gacaagatgg gagtatttac
     2521 aacttgtttg ataggtatta tagatactaa agaaaatatg attactgtgt ctaatgcagg
     2581 tcactatagt cctgtagttg taaagaaaga tggcacaata gaaaataatt taaattgtaa
     2641 aaagggcata cctattggaa taatggaaga tgctacttat gaaaataata ctctttcaat
     2701 ggaagattat gcaatggtat gtatgtacac tgatggaatt ttagagataa aaaattcatc
     2761 aaaagaagag tatggtataa acagattaga aaactttcta aaagaaaatt ttagattaaa
     2821 tcaacagtta atagtagaaa atctaaaatt ggatttaaag aacttctcat caaaagataa
     2881 ttatgatgat gatattttaa tagttatgtt aaaggatagg tagattgatt atggattcaa
     2941 acgataaaaa aggacttaaa agtccagaga ttataataat aaatggaagt ccaagaatta
     3001 ataaaaattg cagttttata gcaaatgaag taaaagctat gctagaagag tgtggattaa
     3061 gttgtaaaat atttaatatc tacaatatgg atattgaata ttgcacagca tgtggatttt
     3121 gtgaaaaaac agggtattgc aagtttaatg atgatatgaa gccattatat aaaatgtttg
     3181 atgattcaaa aggaactata gtaataagtc ctgtacattt tgattcaata tcagctaaat
     3241 taaagactgt tgttgataga actcaagcta tatatgcaag taaatatgta ttaaataaac
     3301 cttcaattga tagaagtaag aaacggatag gaatgtatat tgcagtggga gggagtaaat
     3361 catatgattc acagtttaaa ggtggacaga ttgttatgga ttttttcttt aagagtataa
     3421 atactaaact tttacacaat atatatttaa acaatacaga tgatgtatct tatatagata
     3481 atcaagaatt taaagatata atatataaaa atttaaagat atatattgat tcaatataat
     3541 ttgattttgt aggtaatatt atgtataatt gtattgcaat aatttaaata attaaaagga
     3601 gggaatttca atgaaattac caatagcatt atctaataaa catgttcatt tgagtcaagc
     3661 tgatatagac gtattatttg gagcaggtca tgagttaact aaatttaaac cattatctca
     3721 accagggcaa tatgcctgtg aagaaaaagt ggatttagta ggaccaaaag gaactttaaa
     3781 aggagttaga gtactaggac cagctagagc tcatactcaa gttgaaatat ctttagcaga
     3841 tggtttccca ttaggagtaa aagcaccaat aaaagaatct ggtgatatag ctggaactcc
     3901 aggtgttaaa ttagtaggac ctgctggaga agttgaaatg aaagaaggag ttatagttgc
     3961 ttctagacat atacatatga gcaatgaaga tgctgctaaa tttggtgtaa ctgataagca
     4021 aatagtaaaa gttaaaacat ctggaccaag agcattagta tttgaaaatg tattagtaag
     4081 agctagtgac agctttaatc tagaaatgca tgttgatatg gaagagggaa atgcagcagg
     4141 cgttaaaaat ggagatttag tagaattaat agttgattaa tattataaat agactttatg
     4201 ctagtagata ttttatttgc tagcatattt ttaaatgtaa taaatttcta taggataaat
     4261 ttaatcaatt agattaattt ataaaataaa ggggtattat aaaaaatgta ataaaaactt
     4321 acaaaaatat gatgtaatat ggtaaaatta tatatataaa aatttacatg taataaggat
     4381 aagcatttta ctttttatac taatatgaac aaatagataa aaaagtttga aaaatctaac
     4441 ttaatttatt atatattgta tacaaaatta tgaaaaaaac ttaacatatt taattttaaa
     4501 aaaaatctac ttaaatatgt aattaattta caattttcaa aggaatttta tctaatctgt
     4561 agtattatat tagaagatag agtatttgcg cgactatatg tgtgtttata gttttgttgt
     4621 gtaaattata tgtaaatata aaaaaataga cttgttataa acaagtacaa ttgtagctat
     4681 caaggaggat acatattatg gctaagttta tgaaaacact tgatggaaat acagctgcag
     4741 ctcatgttgc ctatgcgttt acagatgtag cagctatata tccaatcaca ccatcttcaa
     4801 ctatggctga agtagttgat gagtgggcat cacaaggaag aaaaaatata tttggacaaa
     4861 cagttaatgt tgttgaaatg cagtcagaag caggtgcatc aggaacattc cacggttctt
     4921 tacaaggagg agctttaact tctactttta cagcatctca aggtttatta ttaatgatac
     4981 ctaacatgta taaagttgca ggagagttgt taccaggagt attccatgta agtgctcgtg
     5041 ctttagcatc tcaagcttta tcaatatttg gggatcacca agacgttatg gctgctagac
     5101 aaactggatg tgtattatta gcttctggtt cagttcaaga agtagctgat atagcacctg
     5161 ttgcacattt agctgcaata gaaggtagat taccatttat acatttcttt gatggattca
     5221 gaacttcaca tgaaatccaa aaagttgaat tactagaaaa tgaagattat gcaagtttat
     5281 taaactttga agcagttcaa gcatttagag ataatgcttt atctccaaat catccagttg
     5341 ctcgtggtac tgctcaaaac ccagatatat atttccaaac tagagaagct tctaataaat
     5401 actatcaaaa tatagtaggt atagttgaaa aatacatgga aaaaatgagt aatttaacag
     5461 gtagaaaaca tagtttattt gattactatg gagcagaaga tgctaaatac gtattaatag
     5521 ctatgggttc agtaacagaa acaatagaag aaactataga ttacttaaat gctaagggag
     5581 aaaaatatgg tttagttaaa gttcatttat atagaccatt ctcaatgaaa catttcttag
     5641 atgctatgcc atctactgtt gaaagaatat gtgtacttga tagaactaaa gagccaggtt
     5701 caactggtga accattatac ttagatgtac gtgatgtatt ctatggaaaa gaaaatgctc
     5761 ctatgataat aggtggaaga tacggattag gttcaaaaga tactactcct tcagatataa
     5821 aaactgtttt tgataactta gtttcagaac aacctaaaaa tggatttaca gtaggtatag
     5881 ttgatgatgt aactaatact tctttaactc catctgagcc aataaaaata gcttctaaag
     5941 gaactataag atgtaagttc tggggattag gttctgacgg tactgttgga gctaataaac
     6001 aagctatcaa aataatcggt gaccatactg aaaaatatgc tcaagcttac tttgattatg
     6061 actctaaaaa atctggtggt ataactatgt ctcacttaag atttggtgat actccaataa
     6121 gagctactta tttaatagat gaagctgatt atattgcctg tcataaacaa tcatatgttt
     6181 atcaatatga tttattaaaa ggtcttaaaa aaggtggtac atttgtactt aacactatat
     6241 gggaccaagc aggacttgaa gaacatttac cagctcatat gaaacaatat atagctaaaa
     6301 atgatataaa attctataca gttaacgctg ttaaactagg acaagaaata ggtcttggaa
     6361 acagaataaa catgataatg caatctgcat tctttaaatt agctgaaata ataccagaag
     6421 aagatgctgt taaatactta aaagattcta tagttaaagc ttatggtaaa aaaggtgaaa
     6481 aaatagttaa catgaactat gctgctgttg atgcaggaat aaatgcttta gttaaagttg
     6541 aagttccagc ttcttgggaa aatgctgttg atgcagataa aggagaagtt aaagaaccag
     6601 aatttataaa aaatatacta agaccaatga ctgcacaaga aggaaacaac ttaccagtaa
     6661 gtacattcaa tggtatagaa gatggaacat tcccttgtgg tactgcagct tatgaaaaac
     6721 gtggtatagc tgttgatgtt cctgaatgga taatagataa ctgtattcaa tgtaaccaat
     6781 gttcttttat atgtcctcat tcatgtataa gaccagtatt agttactgaa gaagaattag
     6841 ctaatgctcc agaaggattt gaagctaaaa aagcattagg taaaggatta gaaggattaa
     6901 aatatagaat gcaacttagt ccacttgact gtacaggatg tggaaactgt gctgacatat
     6961 gtccagctaa agaaaaagct ttagttatga agccaataga tactcaactt gatacagagt
     7021 tagataattg ggcatttgca gtaaatcctg atgaggtagc tccaaaaggt gatgttatgc
     7081 ctgcaaacac tgttaaagga agtcaattta gacaaccatt aatggagttt tcaggagcat
     7141 gtgctggatg tggagaaact gcatacatta aagtagttac acaattatat ggagatagaa
     7201 tgatgatagc taatgctact ggatgttctt ctatatgggg agcttctgca ccatcaattc
     7261 cttatacttg taaccatgaa ggtaaaggtc catcttgggc aaactcttta ttcgaggata
     7321 atgctgaata tggatttggt atgtacacag ctgttaagca aataagaaat aaaatagtag
     7381 atgctatgac agagttagtt tctatggata tctgtgaaga tgctaaagcg gtatttacag
     7441 agtggttaga ttctagaaat gatggagaag cttctaaagt agcaagtgct aaggttgttg
     7501 aattattaga aaaaccagct tgtgattgta cagatgaaaa agctaaagag ttagtaaaag
     7561 ctataaaaga tagaaaagat tatctagtta agagatctca atggatacta ggtggagacg
     7621 gttgggcata tgatatcggt tacggtggat tagaccatgt tcttgcatct ggtgaagatg
     7681 taaacgtact tgtatttgat acagaagtat attcaaatac aggaggtcaa gcttctaaag
     7741 ctactccagc tgctgctatg gctaagtttg ctgcttcagg taaaaaatct agaaagaaag
     7801 atttaggaat gatggctatg acatatggaa acgtatatgt agctcaagtt gctatgggtg
     7861 ctgataaaaa ccaatttatc aaagccgtta tagaagctga aaaacatgat gggccatctt
     7921 taataatagc ttatgctcca tgtataaacc atggattaaa agaaggtatg ggaagaactg
     7981 tagctaacga agcacaagct gttgcttgcg gatactggca tttatacaga ttcaatccag
     8041 aagtaaaagc tgaaggtaaa aacccattca ctttagattc aaaagaacca actgcaagct
     8101 tcaaagattt catacttgca caagtaagat attctgctat agctaaacaa ttcccagagg
     8161 aagctgatgg attatttgct aaagctgaag ctgatgctaa agaaagatat gaaggataca
     8221 aaaaattagc tgaataatat taaagtatta taatgcttat atagaattga taaaagagag
     8281 tgtctcaaag tgagcttttt agttcatgag gcactctttt tgtatgaaat caaatatatt
     8341 ttaatcattt caacaatgaa aaaggcctta tctctatttt gagacagcct ttttttatga
     8401 agatattaag atcctgtttt tacctattaa atatcttttt aagttttcca ttttcatctt
     8461 gccaatactt tttatatatt gctctacaca ctaaaattaa gagaacaaat aatatttata
     8521 gtatgtatat ttggatttga taattttaaa atagatacaa aagagtatct catttgtgtt
     8581 ttttatcact tagagataat cttttgatat gtatggaaaa agattatttt atcctacaaa
     8641 gatttgtgtc caataaattg aaccaccact tttttgtgct actccaacac ctattttact
     8701 gaaatttgga ttcattatat tttttctgtg accttcagaa ttcatccatg catttacaac
     8761 ttctttagga gttttttgac ccatagctat attttcacct gctgtcttat agcttattcc
     8821 aaattttttc aacatgtcaa atggagaacc ataagttgga gaattgtgtg aaaaatagtt
     8881 gttatcaatc atatcttgag atttttttgt agcaacattt gatatagaag aatcaagagt
     8941 aagaggattt aatccagctt tagctctttc tatatttact aagtcaacaa cttctttttg
     9001 gtaagctgaa aaactttcac ttgtagagcc tgagttgtta ttatcatcag gtttgttagt
     9061 agagtctgaa ttattgttgt cttcaggttt atcagtagag cctgaattat tgttgtcttc
     9121 aggtttatta gactcaggtt tattattatc aggtttatta gtagagcctg aattattgtt
     9181 gtcttcaggt ttattagact caggtttatt gttaccaggc ttattagtag agtctgaatt
     9241 attgttgtcc tcaggtttat tagtgttgtt gcaattcttg tcattatgat tcttatcctt
     9301 acaagagtta tctttatcag gcttaagttc tggttttaca gaacaatttg gttttgcaga
     9361 aaacttgtat ttagtattac tatatactaa acttttgtta cttatattta cattattttc
     9421 aagtgatgaa gcacttgcag taacagcact tgaagctgtt gctaaagtta acactcctaa
     9481 agctaatata gtttttaatt ttgttggtat atttcttctc atcattaaac acctcttaat
     9541 ctaaaaattc taaaaatgtt actgatttgt aacctttagt gtagggggtt acccgtgaat
     9601 ctatactaac ataagattaa gacttttttt actgtaaaga tatgtaaaaa agatatatat
     9661 ggaataaata ggtatatttc agtgtgtttg acaatttgta ttaaaagcct gtatagtatg
     9721 gaattactta gttagagaaa ataatatttt tataataatt ccataacgta aatttatagt
     9781 tatgataaat ttttttttat ttggttaaat ttattcagta gatgctttcg tattagcaac
     9841 aaattataat tatttaaatc tttaagaaat aaaaagggtc tgtctcaaaa tagagataag
     9901 gcctttttta ttgtttaaat gataggcata tgttatttca tataaaaaga gtgtctcatt
     9961 aagtaaaaag ttcactttga gacaccacct ttcatattat gaattttaat ttgttttata
    10021 ttaatacatt agtaatccta atgtaattac aataatttct gctattagtg aaccaactgc
    10081 aactacaatg aaagtttctt taaatccagt tttatgtgtt aacttagata agcttaagaa
    10141 tgtaagaaaa acaccacttt gtggaactat agttagtata tttgaagcta ttgtagcaac
    10201 acggtgaatt aattctggat ttagaccagt acttaaataa taatctgcaa agtttggcat
    10261 tactattcct aatgcaccag aagaggaccc tgttattgct gacattgttg aagtcaaaac
    10321 agtaagactt ataagtggac tacctggtat tgacattata agtttgctaa atacatcaaa
    10381 accaggtgca gccattatta ctgctccaaa tgcaactgca gaagatgtag caaatatagg
    10441 acctatagaa ccactagcac ctatgctcaa tgtctgtatc ttagatgata gaaatttatg
    10501 gaataaaaaa gcagataaaa gaattgcaac tattaaagct atgtaaatta catttttttt
    10561 cataaattct gaaccaaaag tacttccagt tatagctata attacgagtg ctaatagagg
    10621 aaaaatactt gcaaaaaatc ctggtaattc tctatctaaa gattcttctt ctaattctga
    10681 agtataagtt gcataagttt caccttttct aatacttttg tttagagcat atttcatata
    10741 gacaagtcca aacgtagcac aacctatact acctacaata cttggtatag tagctgcagt
    10801 aagagacgta tttagatatt gaataggtat aacattttga atggctggtg ttccaggaat
    10861 tatagtcata gtaattgttg caataccaag ccaaagtggt atctgaataa ggttccaaga
    10921 aatatcaagt tttttaaata gagttcttgc aagtggaatg accgcaaaca taactacaaa
    10981 taagcttata ccaccatacg ttaatataaa acttactata aatatagcaa ctaaaactct
    11041 ataaggatga ttagagccaa atttatttaa aataaaatca gctattgata cagtagctcc
    11101 actttcttcc ataaatttag caagtattga gcctaataag aatattgcaa aataactcat
    11161 tatatagttt ccaagtgcac ccatataatt gtttttgtca gcacctagca ttgatgttac
    11221 aacatccatt ttatttaaaa taacaactat taaagttgct attggagcag ctatagttat
    11281 atgaatttct ttaactgaaa aatatataat agctatgata ccaataatta taccaattgg
    11341 tgcgataata ctcataaata tccctcctta gtagaaggac ctgaagaata ctttcttcaa
    11401 gccctaaata taataactat tgtgcagtat atcctccatc tagtaagcaa gcttgtcctg
    11461 taataccctt agcattatca cttgctaaga acatagcata gtcggcaatt tcttgaacat
    11521 ctaataggcg tttttgtggt acaagtgggt ataaaacttc ctctaagaca ttttccaatg
    11581 gtatattacg agtttttgaa aggtcattga actgacctct gacaagtgga gtatctacat
    11641 atccagggca taaagcatta actgttatac cagaatcggc agcttcaaga gcagcaactt
    11701 ttgttagtcc aataagtcca tgttttgctg agttataagc agcctttcca gcaaatccta
    11761 ttacaccatt gattgaggcc atatttatta tacgaccaaa gccttgtttt ttcattatag
    11821 gaaatgcttt tttagtagct ataaaaggtg ctgtcagcat tatttttatc ataaattcaa
    11881 atttatcagt tgggaaatct tctatcatag aaacatgttg aagtccagca ttgtttatta
    11941 atatatctaa tctgccatac ttttcaacag ttttgtctat agcgtggtta atttcttctt
    12001 ccttagttac atcacacttt acactcatgc aatcataacc ttttttttgt aactctgtta
    12061 tggtattatt taaagcttct tgatttatat cagagaacat tactttagca ccatttttta
    12121 agaacgattc agctatttgt ttacctattc cacttgcagc tcctgttacg aatacaactt
    12181 tatctttaac cattttcatt tcctccaatt ttattttatt tttatattaa tattttaagc
    12241 aatacaaatt tatatgtaat acgtctaaga gatttttatt ttctagtttt aattatttta
    12301 aacaacagat atttttccat ttaatgaatc tgacaatatt aaaggagcct cagtagcaga
    12361 aataacatca tctaatgtga aagctggatt tatttcttta agtaaaattc catctgatgt
    12421 tacttccata actcccattt cagtaactat caaatctaca gcatttgttg cagtaagtgg
    12481 aagagtacaa ttatttaata tttttgcaga accttttgaa gtatgttcca ttgctacaat
    12541 aactttttta gctccagtta ctaggtccat agctccaccc atacctggaa ccatcttacc
    12601 tggaatcata tagtttgcta tattaccata tttgtcaacc tgaagtgcgc caagaacagt
    12661 tatatcaaca tgacctcctc tgattattcc aaaagaagta gcactatcaa agaaacatcc
    12721 tccaggaagt atagtaactg gttgaccacc tgcatttaca atagtttcat cacttgaatt
    12781 tccatcttcg gctgaaccta aacctaaaaa gccattttca gattgtaaga taacgtttac
    12841 attatccgga atataatttg ctactttggt tggtagacct attccaaggt ttacaacggc
    12901 tccgtctttt aattctttag atactctatt tgcaatatat tcttgcattt ctaatttatc
    12961 cattataaat tacctccttc aatgatgtaa ttcacaaaaa tacctggtgt attaacttca
    13021 tttgggtcaa tatcaccaat ttcaacgatt tcatctgctt caactattgt aattttggca
    13081 gcagatgcca ttaaattatt aaaattgttc atagagcctt tataaactag attacctgct
    13141 ttatcgacct ttgatgcaaa tagaagagca acatctgcat aaattggttt ttcaagaagg
    13201 tattctttgc tatcgacaac aattttttgc tttccctcct caacaagagt accaatacca
    13261 gtcggtgtga gtatacctcc tagaccataa ccagctgcac gtatttgttc agcaagagtt
    13321 ccctgaggaa ctaactcaac atctgtttca ttgttattca tttgtcttcc agtttcttta
    13381 tttaatccta catgagaagc aattatcttt ttaaattgct tatttacaac cattttgcca
    13441 actcctttgt caataaagcc agtatcattg caaattagtg tcaaatcttt tatattttta
    13501 ctacataaat aatcaattaa attttctggt gaaccattgg ccatgaatcc accaaccatt
    13561 attgtatctc catcttttac atgagataga gcttcatcaa tgctaactat tttattcata
    13621 tttcctccta tcgtgaaacc accattgata ttccttgacc accaccaata caaagtgttg
    13681 caagtccagt ttcaacttta cgtttttgca tttcataaat taaggtaaca agtattctag
    13741 ctccacttgc tcctattgga tgtcctaatg ctattgcacc accattaaca tttaactttg
    13801 atgaatctat ttgaagttca tttttaacag ctaatgcttg ggcagcaaac gcttcatttg
    13861 cttctattaa gtctatatca ttgatgctaa gtccagcttt tttcagtgct tttctagttg
    13921 cagggattgg accagtaccc atgacttcag gttcaacacc agctgaagca taggatttta
    13981 ttttagcaag tggtctaata cctagttcgt ctgctttttg ttggctcatt agtattaaca
    14041 tagccgcacc atcattaata cctgaggcat ttccagctgt tacagtacca tcttttttga
    14101 atgcaggttt aagtttagct aaaccttcaa atgtcatacc taatttagga tattcatctt
    14161 tatcaatagt ttctattttt cctcgacgta ttaaaacatc tactggaacg atttcttctt
    14221 taaagcggtt gttttttata gcattctcag ccttactttg actttctaat gccaatttat
    14281 cttgcatttc tctagtaaat tcaaatttag ttgcaatatt ttctgcagtt attcccatat
    14341 gatactgatt gaaagcatca ataaggccat ctgttagcat actatctacc atggttatgt
    14401 cacccatttt actaccaaag cgagcagttg gaacgatata aggagcttgg ctcatatttt
    14461 cagtaccacc tgcaattacc acatcatttt caccagatgt gattgattgg gcagctagct
    14521 ggacactttt aagccctgaa ccacataatt tatttactgt gtagcttgga acagaatttg
    14581 gtatacctgc atttatagca atttgtctag caacattctg tccaagccct gtttgaagaa
    14641 catttccaat tattacttca tctatttcag ataaattaag tcctacacgt gatatcgctt
    14701 ctttaacagt gatagttcca agttgaacag ctgaagtatt tttaaataca cctccaaaac
    14761 ttcctatagg tgttctgact gctgatacga ttactacatc tttcatatct aatagttacc
    14821 tttcttgaat gataattaaa aattttctga ataaagaaat taggaaacac tataataaag
    14881 tactttttta atacaagctt gtttttaagt atttcaatta cttttattcc taatgcttta
    14941 ggttttcctg tttctaatta tagattacgg cgaaaaaagc gttttgtcta agtctaattt
    15001 tttatatagt gtataagaaa aatttatagg ataaaaattt atagtagatt tagaaaaata
    15061 ttttgttaaa atattaatga aattatgttg attttcctat aaaatatcat tagaagaaaa
    15121 aatataatct aaattatact tttggggaag ggggtttaaa atggatataa aacagttgaa
    15181 atattttgtt gaaatagtga aatctggttt taatttatca atagcatcta agacacttca
    15241 catatctcaa ccagcattaa gtcaaattat aaaaaatttt gaagaaagtg aagatgtata
    15301 tttatttgaa aggtataaag gcaggttaaa tgggttaaca ccagcaggag aaagatttta
    15361 tgtaaatgca gaacatatca taaatgaata caaaaatatg atggaagatt taagagaaga
    15421 ttcagttcaa tttaaaggaa aagttagaat aggaatacct ccacttatac ttggaatagc
    15481 attttcagat gtagttgcac agttagttgc aaataatcca gatatagaat ttgatatagt
    15541 agagaagggt gcatatgact taaatagaat gcttatctta caggaattag attatgcagt
    15601 attgttacat ccacataaaa ttgataaaag tgtagtaact gaacatgtgc ttcaagaaga
    15661 tgaacttaca gcatttttaa atataaatca tccacttgct aagaaggata agatagattg
    15721 gaacgatttg aatgagcagt tacttgcaat atttaatcct acttttatga tacatcataa
    15781 gctaatgcaa aaatttactg atgaaaatgt taagttaaaa agatatataa tgtctggttc
    15841 atgggatttt ttgttgctat caaccacaaa ttctgatttt ataacaattc taccatcacc
    15901 agttcatgat ttttttgaaa atagcaaaat tatagaaaag ccttttaatc atcctattac
    15961 atggaaagtt atattatgta gacctaaaaa agaacgttat agccatgtag accaacatgt
    16021 atttaaattt attatagatt tctttagtaa aaagaactct taaaaatgtt attaaaataa
    16081 caaataaata aatcaatttt tattataata aactattagt ttttcatcta tatgtttgag
    16141 agcaataata ggttttacat aacatggtag agtagtattt aaagttataa tatacaaaat
    16201 atgtattttt ttaaacgaaa aataaaaaca gtgtatatct ttagataatc actgttttta
    16261 ttttctatat aaaatttgtt aagtattact agaaaatttt ttgcttatta tagtcaaact
    16321 catgactgtt aaaaatataa gtaatcctgg aaatacagct aaatataact tgtcaaaaat
    16381 atgtctttga gcatcttgaa gcatattacc ccatgatgca agaggcaatt ggattccaag
    16441 acctaaaaaa ctaagagcag attcagttaa gatagcatta gcaatattta acgaaccagc
    16501 aactacaata gtctctttta agtttaaaac tatatgtctt aatagtatat ttctagtctt
    16561 gataccagta gctttagcag ctagacagta ttcattttcc tttattttta atgtttcgcc
    16621 acgtacaatt cttgaaactt ccatccaact taagaatcca ataattagta taatagtgga
    16681 aactttaggt gttagataag tatttaatac aatcaaaact aagaaacttg gtatactcat
    16741 aagcatatct attaatctca tcaagaattg gtctagctta cctccaatat atccactaat
    16801 aacacctaca gcagtaccaa atactacaga aataagcatt gataaaatac caacactaag
    16861 tgaaatcctt ccaccataaa gagctctaga gaagtaatct ctaccaagtt cgtctgtacc
    16921 aaagatatgc tttaagctag gttcttgaag tttagaagta gtatcaattg cattagagtc
    16981 tatatttaat ataaaagaag ctataattaa tatgattatt atgctaagag taatacatgc
    17041 aaaagcaaag gatttatctt tttttaattt ttttaagata cttgtaaaca caactagaat
    17101 cctcctttgc tagattttat tttagggtca attaataagt atagtatatc agcaactaaa
    17161 ttacctaaaa ttaaaaatag tgctgataac atagttattg ccataattac agtataatct
    17221 cttgaaaaaa ttgaatcaat cattaatctt cccatacctg gccaagagaa aactacttct
    17281 gtaacaaatg caccagtgac taatttttgt atactcatgc ctaggattgt aaccaatgat
    17341 gtcagtgaat ttttcaagac atgtttaaat agtatgactt tttctgataa tccttttgct
    17401 cttgctgtaa taacatattg tttttttaat tgttcattta cactagcttc tacataattt
    17461 gtaaaaatag cagtattata tagacctaaa gttattacag gcaaaactaa atgttttact
    17521 aagtctccaa tactatcatt tccaatagta tgcatacctc ctgatgggaa aatgttaagt
    17581 ttaactgaaa aaattgaaat gagtatcata cctatccaaa aagaaggtat agaaacacct
    17641 atataattaa aaacagatga tactttacta gttattgaat ttttatttac agctaaaaat
    17701 attccaagag gtatagctac caatattgaa aatatcaaag aagtacccat aagaataaat
    17761 gtatttccca ttttttccat aatttgttct gtaacgggca tatggtttat ataagaaata
    17821 cctaagtttc cacttaaagt gtttttcaac cagtttaaat atcttatata tactggttta
    17881 tcaagcccca tattaaccct tatattttca atatcctgtg aagacattaa aggatttata
    17941 tatgcatctg ctgggtcacc aggagctaat tctaaaagtc caaatgataa tatagatatt
    18001 aagattaaca taggtattaa aacttttact ctattcaata ttaattttaa cataagtaaa
    18061 ttctcctaat taaaagagat gtctcgtttt aaaataataa aacaatatta tttttagaca
    18121 tctccttttc taattaataa tataaaattt tacatcaatt attctacata cagtttagac
    18181 caatcttcaa ataatattgc aggagatggt ttagcatctt ttattccttt tagatttttt
    18241 tgagctgcca ttaaattttg ttcataatct atagtgtaaa taggcgcatc cttagatata
    18301 tcctgttgta tttgcttata tatttcttca cgtttttcct tgtttaactc agtaaatcct
    18361 ttttcccata aagcatctat ttcagcatta gaatatttag tttggttgca atattgacca
    18421 gtttcaaaca tacctctata tgggtttggt tctaatcccc aagcataacc atttacatac
    18481 atatcacatt cagtgctatt actaaatagt atattgaaga atgccttact ttcataagga
    18541 actatttcag cttctatacc aatttttttc aactcttgtt gagctactaa ggcatagttt
    18601 ttatgcccaa atctacctgt gttataacct atttttaatt tatcaatttt aacaccactt
    18661 ttatccaata agtctttagc cttatttgta tcttggtcat atccttcaac accttcttct
    18721 gtatagaagt ctgcttctgg aactaatata gatttagcag gtacagaacc ttcttttcca
    18781 tatgctgatt ctatcatttc atttctattt aaggcatatg ataaggcttg tcttacttct
    18841 ttgttagcca tgtttgatat attttggtta aatacaatgt agtttaatct ttcttcacta
    18901 taagtataag tttgtaagtt tgagtttgat tttgcctttt catatccttc agcagatgtc
    18961 ttcataagtg aaatttcgcc attatttaaa gctgcttctt gagatgcttc attaggaatt
    19021 atttttagcg ctatagaatc tgccttaggt tctccaccaa aataatctgc attcttttca
    19081 aatactatgc tttcaccttt tttccattcc ttaaacttga atgcaccaga accaactgga
    19141 ttattatttt tttctgactt agctatattt gattctcctt caaacacatg ttttggtatt
    19201 ggagaaattt tagatatacc atataagaaa gattcacttg cagttggtaa agtaatctta
    19261 actgttaaat catcaatttt ttctacttta actggtttct cacccaccaa taagtattgt
    19321 cttgatggtg aattttgttt ttcgtctaaa actgtattaa atgtaaataa gacatcttca
    19381 gcagttattg gctttccatc atgccatttt aaattggatt ttaattttat agttaattcc
    19441 ttactatctt taaaatctac tttttctgct aaataattta ctaaatttcc tttttcataa
    19501 gtataaagag gagcataaac tatatttgat gcaagagagt cttctttaac gtttgcaaaa
    19561 gctccattga ttatatctgg gtcacttgcc ataggtatta caacagttcc accagatttg
    19621 cttccactag acttgtcttt atcattggaa gcacaggctg taaatgtaag cattaatgat
    19681 gaaactaaga ttaatgatgc caatttttta aatttcatat tcttataaaa cctccataaa
    19741 ataatattta acacatattt tttattgtat aatagtaatc attattaaat caatatatat
    19801 agaaattaac tattatatta ttataattaa tagaaaaaaa taataaaatg taagaaaatg
    19861 ttgtaattta aatttttata aaatacaatc aaaaggtgta tgttatctta agtaattttg
    19921 ctgagaggag aaaataatga gtaaagcact aattgaggtt aaagatttaa aagtttattt
    19981 tcatacagat aaagggattg taaagagtgt aaatgaagta agttttaata taaatgaagg
    20041 tgaaactatt ggaatagttg gagaatcagg atgtggtaag tctgtaacag ccatgtcttt
    20101 gatgaagtta cttccaacat caaaaataga aggtggagaa ataatctttc gaggcaaaga
    20161 cattttaaag atgaatgaag atgaacttat gggaataaga gggaatgaga tatcaatgat
    20221 ttttcaagaa ccaatgacat ctttaaaccc agcgtttact gttggaagtc aaatcattga
    20281 aggtattatg atacatcaag atttatcaaa ggaagaagct aagaaaaagg taatcgatat
    20341 gataaaactg gtagaaatac caagagctga agaaatatat aattcatatc cacatgaatt
    20401 atcaggtggt atgagacaac gaataatgat agctatggct ttatcatgta atccaaaatt
    20461 acttatagct gatgaaccaa caacagcttt agatgttact attcaagctc agattttaga
    20521 tataatgaaa aatataaaag aaaaattaaa cacatctata atgatgatta cacatgattt
    20581 gggagtagtt gcagaaatgt gtgacaaagt attagtgatg tatgctggca aaattataga
    20641 agtggcagag gttgttgaat tatttaaaaa tccaaaacat ccttatacta ttggacttct
    20701 aaaatcaaag cctgctcttg gaaaaaacaa agataaaaga ttgtattcga ttccaggaca
    20761 agtaccaaat ccaattggaa tgccagattc atgttatttt agtgatagat gtgaaaaagt
    20821 atgtgataaa tgtagaactc agatacctcc tttaatagaa ttgaatagtg gtcatagtat
    20881 tgcatgttgg ttatataaaa aggaggagat ataattgaaa aaagaagaga gtttattaaa
    20941 agtagaaggt cttaaaaagt actttgaagt taaatctgga ttatttgata agaaaattaa
    21001 atctgtaaag gcagtagatg gaatttcttt tgatttaaaa aaaggagaaa ctttggctat
    21061 agttggagaa tcgggatgtg gaaaatcaac tgcaggaaga accattctta gattaattga
    21121 aaaaactgaa ggtaaagttg aatttaatgg tgtagatata tataagttag agaaggaaga
    21181 acttagaaag ttaagaccca aaatgcaaat gatatttcaa gacccatata gttcattaaa
    21241 tccaagatta aatgtggaac aaataatatc cgaggcagtt atagaacata atttagtgcc
    21301 aaagaatgaa ataaaagata atatattaaa tgttgtagaa agttgtggtc tttctaagta
    21361 ccatttaaat agaaaaccag gtgagttttc tggaggtcaa agacagagaa taggtatagc
    21421 aagagcatta gcattaaatc cagaatttat agtttgtgat gaacctgttt ctgcactaga
    21481 tgtttctatt caatctcaaa ttataaattt acttatggat ttacaggata aatataaact
    21541 ttcatattta tttatatctc atgatttgag tgtagtaaat catattgcac atagagtttg
    21601 tgttatgtat ctaggttcta taatagaaat tgcaactaaa ggagaacttt acttacattc
    21661 tcaacatcca tatacaaaag cacttatgag cgcagtacca atacaagacc ctacaattaa
    21721 gaaaaataga attatattaa aaggagacat accatctcca acaaatccac caagtggatg
    21781 taagtttcat acaagatgcc cttattgtaa ggaaatatgc aaaaaagaga ttccagtttt
    21841 aaaagaaata tcaagaaatc attttgttgc atgtcatcta gtatagatat ttcaaaaatt
    21901 aaatttgatg tatataataa gaataataga ataaactgaa aatttttttg attaagatgg
    21961 gatttcatgc tgttaatatt aagttagttg atatataagt ttaatctata atattattat
    22021 tgaaaagaga ggtagttatg tcaattttag taacattgtt gggattattg gtttgtacaa
    22081 cgatttcaac tgtatttagc aaaaagtgga gtaatattcc tcttgcaata tatcaaattg
    22141 tactagggat tatattgtct attttgccat ttaaattctc attttcattt aatccagaaa
    22201 tatttgtaat atgtatcata gctccattac tattcagtga aggacaaaat gtatcgagaa
    22261 aagagctatt agagcttaga aaaccaattt tgcttcttgc atttggttta gttttaataa
    22321 ccgtgtttgc aggtggaatc tttatacatt ttcttattcc tgggatgcca ttatctgttt
    22381 catttgcttt ggcagcagta atatctccaa ctgatttagt agcagtaaaa tcaattacac
    22441 aaggattaaa ttttcctaaa aatataatga gtatacttga aggtgaatct ttattaaatg
    22501 atgctgctgg agtagtagca tttaaggttg cagtacttgc tacagttaca ggagtttttt
    22561 caatagaaga ggcagggatt caatttatga ttacagcttt tggaggaata atagtaggaa
    22621 gtattttagg atacataatt ataaaaataa gacttagttt acacaagtgg aatttggaag
    22681 aaattccaat ggtaatagtt atacaaataa tgactccact ttttgtatat tttgtagcag
    22741 aagaaatagg agtatctgga atcctagctg ttgtaatggc agggatagct catggaattg
    22801 aaaaagagca tttacaaaat acaactacta aattaaggat aatatcagac aatacttggt
    22861 atgttttgga gtatgtattg aatggatttg tctttacact gcttggtttt ttgttaccaa
    22921 gtatatatac aggacttagt agtaaaaatg aaaatatggc attggaattg acttttattt
    22981 ctactttaat tgtacttatt ttatttgtta taagatttat atgggtatat ttatggcata
    23041 attcttttat aaaacctaaa aagaatcctt taaataattt ttttgtaggt tttttaggtt
    23101 ttaaggatga agaagttata aaagagagta tttctaaatg taaatactca ctaatagttg
    23161 ctacttgtgg tgttcatggt acatttacac tagcaactgc cttatctata cctttttatt
    23221 tggctgataa agatgtattt ccaatgagag atactgtttt atttatatca tcagaagtta
    23281 ttcttataag tttagtattg gcaacaattt tactgccaag attattaaaa aataacgtac
    23341 aagagtcaga acctttatta tctgataaag aggcatataa actaattttg aaagaagcca
    23401 ttttaaaact tagtaatgaa aaagcacaag aagtacaacc agttatacat gatttaaatg
    23461 aacagttggt agactcagaa aaaggaatac taaatactcc agataataaa cttataagta
    23521 tgatgattgc agaagcagac caacagggat tattagctgt tttgaaacta ttagaagatg
    23581 gtaaaatttc tgatagagcc tttaaattgt atagatttta tattacaaaa tcaagaaaat
    23641 ctgttcaaaa atctatattt aaaattgtaa aattaaaaat aagcatgtgg attataaata
    23701 gaaaagtaaa gaaagaagta aaagaaaaaa ttacaaaaat agtatctgag aataaagaaa
    23761 taatcaaaga gtttcaccat gcatatgcac tttctactaa aactgctata tcatttataa
    23821 ataaaaatac tgatgaagat aacagacatg aggccttaat agcaatcaga ttctataatc
    23881 gttatttgaa ttggattact agaaagattc aaaatgatga taagtttgag gcaagagtag
    23941 aatactacag agtaatggcg atacaaagtc aaagagacag tgttcaacaa ttagttgaaa
    24001 ctaagcaaat atcaagagaa gtggctaaag agttattgga aaatattctc tatgatgaaa
    24061 tgatgatgat agaatcataa atataatgga ataaaatttg atttttgatg ttaaaattaa
    24121 tactaaaaaa taggaaatag ttttcaataa tttacttgac atatatattt atttataata
    24181 gaataaaacc ataaattgaa tacaatatat aagcattaac aagctggatt gttactggta
    24241 agcaggcaat acctaggtta aggtatacag gtgaattgta tcttaattta ggtatttttt
    24301 tatgaataag ggaaattgta ttttgggaga gatattgatt atgattattc aacaaattta
    24361 taataataat gttgtattag ttttagatga aaatataaaa aaagaattaa tattaacagg
    24421 atgtggaatt gggtttcaaa aaaagaaagg tcaagaaata gataaaagta aaattgaaag
    24481 aacttttgta atacaagatg aaagcttttt agataaaatt agtaaactag caagccaggt
    24541 tgatgagaaa ttttttgagg ttagtactga aataattgct tatgcagagg agaacttgaa
    24601 tactaagctt tatgaatata tttatgtagc acttactgac catattgcat ttgcaattaa
    24661 aagatatcat gaaaacataa ctataaagaa tgatttacta catgagataa aaagaataca
    24721 taaaaaagaa tatgagattg ggaaatgggc tgtagattat ataaataaag aatttgatgt
    24781 gaaatttcca gtagatgaag ctggttttat agcaatgcat atagtaaatt caaactataa
    24841 gggaagttca aaggaatcac tattaattac taaaattgta aaagacatac taaatattat
    24901 aagatattat tatagagttg aatttaaaga agatgatata aattatgata ggcttctgac
    24961 tcatttaaaa ttctttgcaa aacgattagt aaaaaaagaa aaaatcaatg atacaaataa
    25021 tgaaattata gatataatta aagtaaagta tgaaaaggat tatgattgtg catataaaat
    25081 aaaaactcat gtagaaaaga attatgatta ctatgtaagt caagatgaac tactttattt
    25141 aacattacat atcaaaagag ttatatctgt actgaattta taataaagag tagtttaata
    25201 cagaatgtat agatttaata tattatgttt aattttaata tattatttaa aatttaatat
    25261 aaaataataa ttttaaaaca ttaagattgt tactgataat gcaggcaaga cttatgttta
    25321 taaaaaaatt ataatagttt atttttaatt ctgaaattag gttaatatag gtttatttat
    25381 attaacataa gtttaatttt agaattaagt atactaatgt aactttttat aaacttaagt
    25441 cttttttatt taaaaaaata taaaataata aggagagaaa agtaaatgaa aaaagtattt
    25501 ggtgttttac aaaaagtagg aaaatctcta atgctaccag ttgcattact tcctgcagca
    25561 ggtatattac ttggcgtgag taatgcttta gcaggagacg cattgttggc tcattttcca
    25621 gctttggcga atcctacatt tcaacttata ataagtataa tggaaagttc aggtcaaatt
    25681 atatttaata acttaccact tatatttgca gttggggtag ctgttggttt aactgaagga
    25741 gaaggtgttg cagcattggc agccatagta ggttttttaa ttctcaatac atctatgggt
    25801 gttatggcag gtgttacaga agatatggta gacaattcta tgtatgcaaa tattgttgga
    25861 ataccaacaa ttcaaacagg ggtatttggt ggcattatta tagggatagt ggctgcttat
    25921 ctttataaaa agttttataa aattgaatta cctcagtatc taggtttttt tgcaggtaaa
    25981 agatttgtac caatcgttac ttcattagtt gctatagcaa taggaattat attgtctttt
    26041 atttggcctc caatacaaga gggattactt agtttctcaa aaaatgttat agaagcaaat
    26101 caaacactag cagcatttat ggaaggttct ttggaaagac tattaatacc atttggtttg
    26161 catcatgttt tccataatcc attttggtat caatttggag aatatgtaaa taaagctggt
    26221 gagcttgtaa tgggtgacca aaagatattc tttgctcaac ttaaagatgg agtaaatttc
    26281 acagcaggta cttttatgac aggtgcattt ccatttatga tgtttggtct tccagcagca
    26341 gctcttgcta tggtgcatga agcaaagcca gaaaagaaaa aatttgtagc aggtataatg
    26401 gcatcagcag cattaacctc ttttttaaca ggaataaccg agccaataga gtttgcgttt
    26461 ttatttgttg caccagtatt atttgcaata cattgtttat tttcaggttt atcatacgca
    26521 attatgcaat tattaggagt taaaattgga ttcacatttt caggaggatt aatagatttc
    26581 ttattatttg gtgttcttcc taatagaact ccatggtact tggctatctt ggtaggtatt
    26641 ggttttgcag tattatacta tagtgtattt agatttatga taagaaaatt taatttaaag
    26701 acaccaggaa gagaagatga gtcagaaact aacgctgaag tcattgaaat gtctaagaat
    26761 gaattagcat cagagatttt gattgcttta ggaaataaag acaatttaaa gagcctagat
    26821 gcgtgtataa caagacttag attggttgta aatgatataa ataaagtaga taaagaaaaa
    26881 ttgaaatcac ttggagcagc aggtgttatg gttattggca acaatgttca agctatattt
    26941 ggaccaaaat cggattcaat aaagtctgat ataaaagata taatagaggg aaaaacaaag
    27001 gttgaaagta ctgttactaa aaatgttgat aaaaataaag tgaaaaaaaa tatggaagtt
    27061 gcaaatatgg aaaatgcttt agtagaaaag attgattcat taacaaatgg agagatatta
    27121 gatatagaag aagtgccaga ttctgtattt tcaagtaaac tgatggggga tggatttgca
    27181 attaaatcta gtgatggatt gatttattca ccagttgatg gaactattgg agttatattt
    27241 ccaactaagc atgcaataat aataaaatcc caaaaaagtg gagtagaaat acttatacat
    27301 ttagggatag aaactgtaaa tttagaagga aatggatttg aagtatttgt gaatgtaggg
    27361 gatgaagtaa aagcgggaga aaaattagtt aaaatggact tagaatatat tgaaaaaaat
    27421 ggtctatcaa caataagtcc tgtagtattt acgaatttag aacaaaatca gaaattaagc
    27481 attaaaaaag gagtaagcac agcaaaagag gagaatagag taagtatatt aagagatgat
    27541 attgaaaaaa taggatagct atatgatagt gtaactaaaa gttatgtggg atttaataaa
    27601 tatataaata ggttcagtta acatgcaatt tatttaatat atattttaag taatagaaat
    27661 atatatcatt atattttgat atattttaaa acattaaaaa acttgaggta ttagtaagat
    27721 aaatacacta atacttcaag ttttattaaa ataaaattta cataaattat ctattcatct
    27781 aaaagagtaa tatccaaagg atttttattg tttatataat ttttaggaga taccccgtag
    27841 ttttttttaa atgcccttac aaaactagaa taatcgttga atccacattt attacaaact
    27901 tcactcataa ggtgaccatt ggttattagt gactttgcca aaattaatct tttttgaact
    27961 atataattgt gtatagacgt tccagtatga gatttaaatt ttctcataag ataatactta
    28021 cttataaaaa attcagacga tatgctatct attgaaagct tatcatctat atttgaattt
    28081 atatagttta atactttctt aatagtttca tcataaaaaa catcttctgt tgattccata
    28141 ttttcatttt ttaggaaaat tctgtttaag aatatcataa gttgtataaa taatgcattt
    28201 ctcaatattt catttccaaa ttcagtattg gattcggaaa tatttatttg ctcaataaaa
    28261 ctcttaatag attcaatatc atgtatattt aaacgcaatc tattgcattt attctctgta
    28321 gctattttaa aacatttttc taagtcacta ctagcatcac tatttttttt cataaattct
    28381 gggctaatcc atattgcaat tctctcataa aagacatttg aatctataac tggtttatgt
    28441 atttcattat tgctgataaa gagtatatcc caaggcttta gtttataggg aataccatca
    28501 acaaaataag ttacatttcc atttataaat ataattatct tattaaaatc atgattatgg
    28561 tattcaaatt gtatatcttt tttatctcta atattaaata ttttaaagtt atcgtttaag
    28621 tacccgattt tattatccat agtttttata gaagaccttt cctcagttat attatagaaa
    28681 attatagagc attttttgca atgtttcaag catttttaac cattcacata gtaaaaaatt
    28741 cttaatataa tattatatgt agtgtaattt tagcagaaag agtttaaagg gaggaaagca
    28801 tttatgaaat taaatgatat tatacagggg ttggatataa tcaatatcaa gggtgaatta
    28861 aatatagata ttaataatgt acaatatgat tcaagaaagg ttacaaaagg tacattattt
    28921 atatgtataa aaggatttgt gtcagatggt cataagtata taaaagatgc catagaaaag
    28981 ggagcaagtg catttcttgt tgaagaagat gtagaaataa aaggatgtac atttataaag
    29041 gtaaaagata caagaaaaga tatggcaaaa gtagctgata atttttacaa tcatccatct
    29101 caaaaattta acgttatagg agttacaggt actaatggaa aaactagtat aactactata
    29161 ctaaatgaga tattaacttt aaataagaat aaagttggac ttataggaac tataaaaatt
    29221 tttgatggag aaaaagacat tgtttccaat tcaacaactc cagaaagtat agatttacaa
    29281 tatcatttta ataatatgtt ggataatgga tgtgactact gtgcgatgga agtttcatca
    29341 cattcattgg cattaaatag agttgatgaa acagacttta aactaggcat atttacaaat
    29401 ttaacaccag accatttaga ttttcataaa gatttagagg attatagaaa agcaaaagaa
    29461 aaattatttt ttaagactac tatggcaaat ataataaaca tagatgatga aggtggaaaa
    29521 aagatatatg aaaatataaa aggtataaat gtaccttgtt acacttatgg tgttgatact
    29581 aaggctgatt ttatggctag agatataaaa tcagattcgg atggagtatc ttatagatta
    29641 ataacacctt catatgaaga agtaatattt ataccagttc caggaatgtt tacagtatat
    29701 aatactttag cagttatagc tgcttgctat gtacttggca tacctaaacc aatatataaa
    29761 gaaggcctta gactttctaa tggagtatca ggaaggtttg aaacagttcc aaatgataaa
    29821 ggtataagcg taattgtaga ctatgctcat actcctgacg cacttgaaaa tgtactaaag
    29881 acaactcaac aatttgcaga aggaaaaata atttctgtgt ttgggtgtgg tggagataga
    29941 gatactgaaa agagaccttt gatgggagca attggacaaa aatattctga tttatgtatt
    30001 ataacttctg ataatccaag aactgaagaa ccagaggcaa taataaaaga tatacttgaa
    30061 ggaattgaca agaaaaaaga aaattaccat gttgttgttg atagggaaca agctatagca
    30121 gaagctataa gtatggcaaa aaaggatgat gttgtaatta taacaggtaa gggacatgaa
    30181 acttatcaaa ttataggtaa agttaagcat cattttgatg ataaagaagt tgcaaatgag
    30241 tgtttaagta agatgtagca taaaaattaa acaaaataca agaacaaaaa tgtaatatca
    30301 agcttcactt tgatattaca tttttttata tgtaaataat tgtaaaatag ataatgcaat
    30361 aatataaaca ctaatatcta tattaattaa tttattgttg taataaagtt tataattttg
    30421 tataattaca gtaaatatgg aaaaataagt attattataa aatgtttaca ataattgtca
    30481 taagataatg attatacata catagattcg agaaaggcag gaagcataat gttaagtgat
    30541 gcaaaaaata ataggtatgg tttgtccata attgctgtca taagtatctt agtaattaca
    30601 atttcctgtt tgatttatgg ttcaaggttg aataagacat taggtgaaga aacgaatcaa
    30661 tatctttcag aaatagcaaa tcaaagtgtc aatgtgttaa aaaaacaaat taatggagat
    30721 ataaagttac tagagtcaat ttcaatattt attgaaggag aagagtcttt tgaagtagat
    30781 aatatccttt ctatactaaa aagacaagct attaatagtt catttaaaag aatgggagtt
    30841 attttaccaa atggtacagc atacactaca gatggttata tagaagactt ctctaaaaga
    30901 gattatttct taaaatcaat gcaaggagaa gtggttataa caggcaaatt aaaagatgta
    30961 atagaagatg ataaaaatac caatagtaat attaatgtat attctgtacc aatttataaa
    31021 gataatgagg ttaaaggagt tatatttgcc acacatagta cgaagttgta tgaaaaaata
    31081 ctttctgtac ctacatttaa tggaaaagga tattcttata taactagaag taatggtgat
    31141 attgttttaa atccaagcag taaaaacgcc aactctacta aagaaaattt attttcttac
    31201 attggcagaa gtgattcaat atcaaaatct agtatcaaca atatgaagtc aaatataaaa
    31261 aactttaaat caggttcatt aagttatagt atgtttggaa aaggatatta tttaagttat
    31321 gccccaatag gaatcaatga ttggtatctt ttttctgaag ttcctaaaac tgctatatct
    31381 gagaaatcat atgctattat aaaacttaca ttatcagcat gtgtagtctt gattataatc
    31441 tttacggcat taacaattta tatactattt atacataaaa agagtaagga aaaattggaa
    31501 gaatttgctt ttaaagataa cgttacaggt attggcaatt caaataaatt taatcttgaa
    31561 gggggaaaat ttttatcctc tcatgagaaa aagaatctag ttttaattta ttttgatata
    31621 gataagttta agctagtaaa tgataggttt gggtatgaag aaggagatag agtattaaag
    31681 gaaatagcag agataattaa gaatatattt aaagagcaat ctgtattttc aagaatttca
    31741 aatgacaatt ttgctataat atttgaaaag aaaaataata gagagtcaat tatagaaata
    31801 tgtgaactta tacgtaaaaa attgtcaatg ataaaaacaa gtttgggagt agaactcaat
    31861 ttaattccat ccataggtgt atattttgtt gaagagggag aaacaaatat ttctacctgt
    31921 cttgacaaag ctatgattgc aaaaactaca gtaaaaagaa aatatttaaa agtttatgag
    31981 atttatgctg aaaatttaaa agaaactctc atagaagaac gtgatattga acaagaaatg
    32041 catgatgctt taaaaaatga acaatttaaa gtttatttac agcctaaggt tgatttatca
    32101 actactaaaa ttgtaggtgc tgaagcactt gtacgttggc aacatcctaa aaaaggtcta
    32161 ataagtccag gtgtatttat tcctattttt gagaaaaatg gctttataac agaattggat
    32221 atgtttgtat ttacccaagt ttgtaaaaat tttaaacgtt gggaaaatga aaatttcccc
    32281 acatttccta tatcaataaa cttatcaaga gtacatcttg agaatccagg ctttatttct
    32341 gagcttgaaa gaataacaaa agaatatgaa attgaaccaa atttaattga gattgaattg
    32401 acagaaagtg caatatttga caatacaaaa atattattta aaataatgca aactttgaaa
    32461 tctgttggat ttaaaatttc tatggatgat tttggttctg gttattcttc tttaaatatg
    32521 cttaaagata tgccaattga tgtattgaaa ttagataggc aattctttat aacagtggga
    32581 aatgcaaaaa agagtcaaat tgtagtttca agtattgttc aaatggcaaa gcaacttgat
    32641 ataaaagttg tttcagaagg tgttgaaact gtagagcaag cagagttttt aaggtttata
    32701 ggttgtgata tggcccaagg atttttattt gctagaccaa tgccaataga agaatatgaa
    32761 aaattaatat tagatagata tagtttaaat agaaaagaaa caaattaaat aaaattgtga
    32821 attataacat aaaaatttat aaaaaagtga actttgttaa tcaatgttca cttttttatg
    32881 taaaaatata ctattataaa aacataaatc attgttagga tattatttta ggaattattg
    32941 ggcaaagttt attaatatgt agtatttttt acatttgaat gtttttgagg taagagtata
    33001 tgggattata gcaaaatact ttagatagta ataatagtaa tttctatagg tgtgttatac
    33061 atattttaaa aaataaaaat ataatttata aatttaaatg ttatatatgt aagtaatttt
    33121 attatatcaa aaaaagagtt tttcataatc atttatacaa atcatttgaa atactcttct
    33181 tttattttta aattctatat aattattata aggtaatatt gtattattat aatcttagtt
    33241 ttttagttat tatatataat agtcaaagtg tatacgatta atcattttaa acattaaatc
    33301 taaataatat tacatctcca tctttaacta tgtattcttt accttctaat ttaaccaacc
    33361 ctttttcttt agcagcagcc atagtaccat gctcaaccaa atcattaaag gctattgttt
    33421 ctgctctgat aaatcctctt tctatatcag aatgtatttt tcctcctgcc tgaggagctt
    33481 tacttccaac ttttatagtc catgctctaa cttcttttgg accagcagtt aagaatgaaa
    33541 ttaaaccaag taaagcataa gaagatttta taagcttatc aagccctgat tgttcaagac
    33601 ctaatgtttc taaaaactct ttcttttctt cagcagaatc aagttcagaa atttctgctt
    33661 ctatttgtgc acatactaca acaacttcgg catcttctgt ttctgcaaat gctttaactt
    33721 gttgaacata tttattattt tctccattat cagctaaatc atcttctgat acatttgaag
    33781 catatattac aggcttagat gtaagtaaat ccaatgaatt tacgaatgtt tgttcatctt
    33841 ctgtaaattc catagttctt acacacttac tttcttctaa agtagacatt attgatttta
    33901 ataaatcaag ttcagaacct aaagttttat cagccttagc agctttttga gttttattaa
    33961 ttcttctttc aagaatctct atatctgaga aaattaattc taagtttata gtttctatat
    34021 cacgaagtgg gtctacagaa ccatctacat gtacaacatt ttcatcctca aaacatctaa
    34081 caacatgaac tattgcatca acttctctta tatgtgataa gaatttattt cctaaacctt
    34141 ctcctttaga agctcctcta actaaacctg ctatatcaca aaattctata gcagtaggaa
    34201 ctattttttc agaattatat aattcttgta gtttgtttaa tctttcatct ggaacagata
    34261 caactcccac atttgggtct attgtacaaa aagggtaatt tgcagattct gcacctgctt
    34321 gagttattgc gttaaatagt gtgcttttac ctacatttgg taaaccaact atacctaatt
    34381 tcatattaat cgtcctctct cttattcttt tttatattct ttatataact ttaaacaatc
    34441 aatctatagg attgcaaaat tgttttaatt atagacatac atattgatta tacatcatat
    34501 atatcaagct tgtaaactag actttaaagc atattgattt aaataatatt tgtatttaat
    34561 ttaaataaaa atattgcttt tagaaaataa taaaaaggat ataattaaat agaaggtttt
    34621 tatatgtgag tatatgtaat taaaaaataa ataaatttca attttaaaat tgatgtttaa
    34681 ataaaaatag gaggtacata tggttaatac taaaaaaata ataaatttag gtaataatat
    34741 taatcttact ttgataaaaa cagaaaagtt taaatcgaat cttataagtt tatatgttca
    34801 gagactattg gatgaaaaag aaactacaaa aaatgctcta ataccatcaa taatagcaag
    34861 tggaagctct aaatatccta gtgctagagc aatatccaat aaattagatg atttatacgg
    34921 ttcatctatg ggagctgatg ctgtaaaacg tggagaacgt caagtattga gttttaaagt
    34981 aattaacata agtgaaaagt atttagatga gagtatattt gaagaagtag tagaattttt
    35041 taatgaagta ataaataata cgcttgttgt agatggtggg tttaaagaag aatatttaaa
    35101 tattgaaaaa gagaatttaa gagaaaagat acaatcaata ataaatgata aaaaggaata
    35161 tgcgcaagat aaatgtattg aggctatgtg taaaggagag agatatagtg taagtgaatt
    35221 tggttatgaa gatgaaatag atagtataac ttcaagagag ttatatgaac attataaaaa
    35281 catacttaaa acatcaccta tagatatagt tgtagaaggt aattttgatg aagataaagt
    35341 tgtagatata ataagtaaaa atctaaaatt tgaaagagaa gaaattataa atataccaag
    35401 agcagatttt ataaaaaatg tggatgaggt aaaagttata gatgaacaaa tggaaataac
    35461 tcaaggtaag ttagttatgg gttatagagc aaatgtggat tatgcagaca tagataaata
    35521 ttatgcttta gtagttggga gcaatgtctt aggtggtggt ccacactcta aattatttgt
    35581 taatgtaaga gaaaaagaaa gtttatgtta ctatatattc tcttcaatag agaagtataa
    35641 aagtatcatg tttatatcat ctggtataga aactaaagat tatgataaag ctgtagaatt
    35701 gataaaaaaa caagtagaaa gtgtaaaagc aggtgatata tctgatgaag aattagaaaa
    35761 cagtaaactt gctttagtta attctatgaa atctataact gataatatag gtggtatgtc
    35821 tgattttgtt ttctctcaat ctatggcaaa gacaaattct gaagtacaag atataatatc
    35881 tagtatagaa aaggttacaa aaaaagatat agttgaagct ataaaaaata tagagcttga
    35941 tactgtatac ttcttgagaa attaatggag gagatgtcta tggaaaaaat agttaatgat
    36001 atattgaaag aagaagttta ttatgagaaa ttgcaaaatg gattagatgt atattttatg
    36061 cctaaaaggg gttttatgaa aaagtatgct attttagcta ctaattatgg ttcaaatgac
    36121 ttagaatttg taccaattgg agaagataag aaaattagag tgaatgaagg tattgcacat
    36181 tttctagagc ataagatgtt tgagcaacct gatggaggag atgcatttga taaattttca
    36241 aaattaggag taaatgcaaa tgcatttact aattttacaa tgacagccta cttattttct
    36301 gctactgaaa atttttatga gagtttagaa catctaattg actatgttca aacaccttat
    36361 tttacagatg aaaatgttga aaaggaaaaa ggtataatag cacaagagat aaaaatgtac
    36421 aatgatgacc ctgattggaa tgtatacttt aattgcttga aggcaatgta tgtaaattat
    36481 cctgctagaa ttgatatagc aggtactgtt gatagtatat ataagataac taaggaagag
    36541 ctatataaat gttataatac tttctataat ccaggaaata tggctttatt tgttgttggt
    36601 gacttagatg tagaaaaagt tatagatgta actaaaaagt caaacaatta caaagtagat
    36661 aaactctcta agagtataga aagattttat ccagaagaac cagaaggtgt aaaagaaaaa
    36721 gaggttatag aaaaattccc tatatctatg cctatgttca acataggttt taaagatagt
    36781 aatgttggtt taaaagggaa agaactttta cgtaaagaga ttgtaactga tatacttgta
    36841 gggatgttat ttaaaaaagg aagtaagctt tatgaagatt tgtatatgca aggtttaata
    36901 aatgaaaatt ttggagctgg attttcgtct caagtggatt atgcttttag cataatagct
    36961 ggagattcta aagagcctaa aaaagtaaaa gaaataattc ttgattatat agaaaaatca
    37021 aaaaaagaag gattatcaaa agaagagttt gagagaacta aaaagaaaaa aatagggtca
    37081 tttattaagt gctttgattc tataaacttt ataggtaata gttttatatc ttatgttttt
    37141 aaggatataa atctattgga gtatttagat gttattaaag atattacttt tgaggaagtt
    37201 gaagaaagat taaaagagca ttttaaagaa gagtattgtg ttatttctat tgtagagcct
    37261 aaatagaaac ttaatcataa taagaataac taattaagta ttagtttatg tttttaaatg
    37321 tttattttgg taaaacaaat ttataaaata tatttatata aattgaggta aaaatttaag
    37381 agctatagat aagaattaga agaggttgat gtatatatgc atcaatcttt ttgattaaaa
    37441 aatatctatg tacacttgta actttagtca tgagagattc agtttaaaaa attttatagt
    37501 aattagatat aatatagtgt agggagttgt agaataaatt ttaatatttt ttgtagaatt
    37561 aacattaatg tgttatcata atttagtata attacaatta attgtaatta tagcatattg
    37621 ctttggaaat attttcaatt aatacaaaga ggtgacgtta tggatagagt agcatttaca
    37681 ctgtttggca tagacatcat gtggtatgga atacttatgg catgtggaat gattttagga
    37741 actttaatag caataaaaga agcaaaaaga gtgggaatta aagaagatga tgtattaaat
    37801 atagctataa tagcaattcc agttggacta atctgtgcaa gaatctatta tgttgtattt
    37861 aattggagtt actatgctca aaatatgtct caaattttta attttagagg tggtggactt
    37921 gctatacatg gagggttaat tggtggaata ttagctggtt atatatacac taagattaaa
    37981 aatattaact tcttaaaaat ggctgataca gttatacttg gaatgccttt agcacaagct
    38041 attggaagat ggggaaattt tattaatgga gaagcacatg gaggtgctac caatttacct
    38101 tggggaataa tggttgatgg agtaaaggta catccaactt ttttatatga gtctatatgg
    38161 gattttggaa tatttatagt tttattacta tttagaaaaa ataaaaaata tgaaggtcaa
    38221 gttatagtta cttatataac tttatattca ataggaagat tttttataga gggattaaga
    38281 acagatagtt taatgttagg accacttaga atggcacaag ttataagtct aattggagtt
    38341 attggtggca taattgcaca tgtttattta tcaaagaaaa ataaaaataa tattagtgaa
    38401 gaatagttta aaaagtgaat ttaagggagg taactatgga atttcatcat gtatcagttc
    38461 ttttaaatga gtgtatagag aatttaaata taaagccaga tggcgtgtat gttgactgta
    38521 ctatgggagg agcaggacat tctaaagaaa tagtaaaaaa actgtcagat aagggattat
    38581 ttatagggtt tgaccaagat aaaaatgcta taagcacagc aaaagagaga ttgagtgaat
    38641 atgaaagtag agtgaagttt gttcacagca attttgaaaa tataaaagag gaattagaaa
    38701 aaataggagt ttacaaaatt gatggtgtat tagctgattt aggagtttca tctcaccaac
    38761 ttgatgaagc tgatagagga ttttcttata tgcaagatgc accacttgat atgagaatgg
    38821 atgttaggtg tgagttttct gcatatgatg ttgtaaatac ttatacagaa gatgaattaa
    38881 ctaagataat aaaagattat ggagaagata actgggctaa gcgtatagct aaatttatag
    38941 ttgaagaaag agcaaacaaa ccaatagaaa ctacaggaga attagtagat gtaattaaaa
    39001 aagctatccc taagaaagct agaatagatg gacctcaccc agctaaaaga acttttcagg
    39061 caatacgaat agaagtaaat aatgaacttg gagtaattac aaagatgata aatgatgctt
    39121 cttctataat gaatgaaggt ggaagaatat gtataataac attccattca ttagaagata
    39181 gaatagtgaa aaatgcattt aagcatttag catcagattg tatatgtcca caacatttac
    39241 ctatatgcca atgtgataaa gaatctgagg tgaaaataat aactagaaaa cctatattac
    39301 ctagtgagga agaaatagaa gtaaatccac gttcaagaag tgctaagcta agagtagcag
    39361 aaaaaatata agtagttata aggctaaaga ataatcttat atataaaata agattattat
    39421 aattaattaa aaagtattat atattttgtt gcactggtaa agcaattaaa aaacaattaa
    39481 cactataaga aatgttcttt gttattgaga tatataatga aaatttagat ataaaaatat
    39541 agatatagat ggtattaagt aatataatgg agaacttagg aatcagagag tagatagtta
    39601 gttacatatt atatttatgg aagaaattat ctaaaaatac tagaagtgat aaaaataaat
    39661 agaaattaat atctaaccta tagattcata taaaagtata agtgaattta taggtttttg
    39721 ttgtgtatag aaaaaaatac aattagattg tgtaatagtg tattaattta gcgatgaaat
    39781 tttagaggaa gaaatatgat taataacaaa tatagtatag aggaaaattt aaactatata
    39841 ctatcggggt gagaatttga aaaaaaatta taaaatacat aatctaaatg aatataaaaa
    39901 taaaaaaaag aataattata aaaagagaaa taagaaaaaa ataggagcta aatgcatttt
    39961 actgattgca actttttcag taataatatt gaatctatgt ggttattcaa aaatctcgga
    40021 aatgaagtac gatatctatt atttacaaaa agatttaaga aaaaaagaga tagtattaga
    40081 ggaactaaag gcaaaagaaa ctgaaaaaac atcaataaaa gaaattgagc taaaggctaa
    40141 ggaattgctc aatatggact atccaaaaga tggacaaata aagtatatag atgtggataa
    40201 ctagggggaa tagatttgag aaaagtaaag aggataagta agaaaaggct ggtactcgtt
    40261 cttattctag catgtgcatt gtttttttgc cttgttatta ggactgggta tctacaactt
    40321 atgaagggaa attggttgag tacaaaagca ctagaacaac aaacaagaga tataccaata
    40381 gaacccaaaa gaggaactat atatgataga aatatgaaag agttagcagt aagtgtaact
    40441 aagtatactg tttggtgtaa acctgtggaa gtagaagata aaaaagaagc agccgaaaag
    40501 gtagctgaga ttttggatga agattataaa gatatttacg ctttaataag caaaaaaaat
    40561 atggctcttg taaaagtaaa aagatggata gatgatgata aggcaagtca aataagagat
    40621 gctaaattaa gtggaatatg ggtggcagaa gataatcaaa gatattaccc atatgggaat
    40681 tttgcaccat atgtgttagg acatacttct tcagatgcaa caggtatatc tggtgtagaa
    40741 atgcaatatg ataaaaagtt aaaaggaaag cctggaaaac ttatagtaag tactgatgct
    40801 tcaggaagag aaataccaca aggaatggaa aaatattatg agcctgtaca aggtaatggt
    40861 cttgtgttgt ctatagatga agtaattcaa cactatactg aaaaagcagt acagaaagct
    40921 tatgagttaa ataatgcaaa aaaggttact gcaatagcta tgaaccctaa aacaggtgat
    40981 atacttgctt tagcatcaaa accagattat gaccctaatg actcaagaac gccaatatat
    41041 ccatattatc aagaagaact tgaaaaatat aatgataaag ataaaataaa aggctattat
    41101 caaatgtgga gaaatccagc agtaagtgat acatatgaac caggttctac atttaagctt
    41161 attacatctt ccagtgctct tgaagaagga gtaattaaag atggagaaaa attcacatgt
    41221 acaggtagtg taactgttgg aggaagaaag attaaatgtt ggagacatta cagacctcat
    41281 ggaacacaag aatttaaaca agcagtacaa aactcttgca acccagtatt tgttgagttg
    41341 ggaagcagat taggtgttgg aaaaatgtat gattatatag aatcatttgg tcttatggat
    41401 aagacaggta tagatttacc aggagaagct aagggaatac tgtataacga aaaaaatgta
    41461 ggaccagttg aattggctac aatatcattt ggtcaatcta tatcagtaac tccaatacaa
    41521 cttataacag ctatatcatc aatagctaat ggtggagatt taatgcaacc aagagtggta
    41581 aaatcttata ctgacaataa aggaaatata actgaaacag taaaaccaaa aaaagtaaga
    41641 agtgttatat ctaaagaaac atctaaaaaa atgttagaaa ttgcagaatc agttgtaact
    41701 gaaggtggag gaaagatagc atatatacca ggttatagac ttggtggtaa aacaggtaca
    41761 gctcaaaaag ttatagatgg taagtatgct ccaggaaaat atatatgttc atttgttgga
    41821 atagcacctt gtgatgaccc gcaaatagta gttcttgcta ttgttgacga accaacagga
    41881 gtaagtgcat ttggtagtac tacagcagga ccaatagtga aagaaataat gaatgactct
    41941 ttaaaatatt tgggagttaa accagtatat aaagaagaag aaaaagctga gtatgaaaag
    42001 aagcaagtta aagtgccaga tgtaagaaat ctaaaaatag gagatgctgt aaaggcattg
    42061 gaggatgcga agttaaaacc agacttagat gcagatatag aacttccaga agatacaaag
    42121 gtaaaggata tattcccaaa acctggagta aaagttaatg aagactcaag tataacccta
    42181 tattttgaaa actaaaaagt aacagataat taacatatac ccataaacat cttcaaaaaa
    42241 acagaaatat agtatataat tataaagtta agagttatcg taggcaatgt atatataacg
    42301 gtatacattg ccttttgttg ctaagagaat atagctaagg ttttaaagga ggagtttaat
    42361 aatggagtgc ttaacaataa aagagttagt acttgcaact aatgggaagt taatatatgg
    42421 agattataat gactgtgtaa gtgatatagt tatagatagc agggaggcaa atgcccaaaa
    42481 tgcatttgta gccatagttg gagaaaattt agatgggcat acatttatga agtctgcata
    42541 tgatagtgga tgtaaaactt ttataaaaaa tgaaagtaat ggaataaaat tagaaagttc
    42601 ggatataaat ttaatagagg taaaagatac atctttggct ctaggagata tttcaaaata
    42661 ctataaagaa aaatttgata ttccatttat aggtgttaca ggtagtgtgg gaaaaactac
    42721 tactagagat atgatttact ctgccatatc tgcaaagtta aatatactaa aaaatgaaaa
    42781 aaacttaaat aatcattttg gagttccatt gactttattt aatctaaata aagaacatga
    42841 gtgtgctgta atagagatgg gtatgtctgg attcaatgaa ataaaatatt tagtggatat
    42901 agtaaatcct aaaattgcag tcatatcgaa tataggatta tcacatgtag aaaaactagg
    42961 ttcacaagag ggtattttga aagcaaagat ggagattact tcaaactttg atgaaacaaa
    43021 tactttaatt gtaaatggag atgataagtt tttatctaca ttaaaagaaa aagaacatgt
    43081 atataagtta aaaacatttg gctttaataa aaacaatgat gtttattgtg aaagttatac
    43141 tatggaagag gatagtttaa catttatatg tgtaataaat gggaaaaaag aggaaatatt
    43201 tataccaaca ataggagaac ataatatata taatgcaatg tctgctatat tagttggttt
    43261 gtgtctaaat atttctttag attatataaa aaaaggttta aaaaatttta aagggacaaa
    43321 aatgagatta gacataataa aaaatgaaaa attaacaata attaatgatt catataatgc
    43381 tagtccagat tctatggatg ctgctttaaa gatacttgga agatataaag gtagaagggt
    43441 agcgatactt ggagatatac tagaaatggg tgaaatttca gagtatggtc atagattagt
    43501 tggaaaatca tctatgaata atactgatat tataataact ataggtgaaa attcagtgtt
    43561 tattggagaa gaagcaaaac aattaggatt caattcagcc aatatatatc actttgagaa
    43621 tagagaagat gtgtttaaca agttaaatga attagtaaaa acaggagaca ctattttagt
    43681 aaaaggctca agaggcatga gattagaaaa aatagtcgaa tatctaaata aataagctta
    43741 aactaatgag ttaattgaca agggagagga gttttatgat gttaggaata acagagctta
    43801 cgtacaccgc attgattgcg tttttaatag taattataat aggaccaata tttataccaa
    43861 tgcttagaaa atttaaattt ggtcagacag ttagagatga tggaccccaa acacatctag
    43921 ctaaaaacgg aacacctact atgggtggaa ttataatgat tgttgcaatt ctaataactg
    43981 gacttacaag agtaaaagtt agtcatgata tggcagtagg tcttatatgt attgcaggtt
    44041 ttggttttat tggcttttta gatgatttta taaaaataaa gctaaaaaga tcacttggac
    44101 taaaagcata tcaaaaaata atccttcaag ttgcattatc tttttatgtt gctttttatc
    44161 agtatacatc atcatcaagt gcttcacaac ttatgatacc atttacagat tttgtgataa
    44221 atgttggaat attatatata ccaataatga tgtttataat cgtagcaata gtaaatgctg
    44281 taaacttgac tgatggatta gatggattag catcaggagt aacattaata gtttctgtat
    44341 tctttatgct atttgcaagt tctattgctg gaaatacaga agtcgcagtt ttagcagcag
    44401 caactgttgg agcatgttta ggtttcttag gatttaattc atatccggct agagtgttta
    44461 tgggcgacac aggttcaatg gcattaggag gtgcagttgt agcattttca gttctaacta
    44521 actcagtgct tataatacct ataattggag gaatttattt tgcggaggct ctatcagttt
    44581 tgattcaagt tggatatttt aaggcaacaa gaaagagatt ctttaagatg gctccaatac
    44641 accaccactt tgaacagtgt ggttggccag aaacaagagt tgtatttatt ttttggatta
    44701 taacagttgt tttagcttgg ataagtataa tagcagtatt ttagggctag ggggaatgaa
    44761 aaatggactt aaaaggaaaa aaagttttat tagtaggact tgcaaaaact ggtatatcta
    44821 caattaaaca tttagataaa ttgggtgcaa gtgtaatcgt aaatgatata aaagatgaaa
    44881 ataaattgag aaatatactt gatgaattga aatctataaa tgacataaaa tacatattag
    44941 gacatcaccc agaagatgta gatgatatag atatggttgt agtgtctcca ggtgtaccac
    45001 tagacctacc attcatattg aaattaaaaa attcaggcaa gtatataatt ggtgaggtag
    45061 aattagcttt taaactatcg aataatccaa tttttatagg gattacaggt acaaatggaa
    45121 agacaactac aactagtttg gtaggagaaa ttttttcaag agcaaaacga gatacatatg
    45181 tagttggtaa tataggaaat cctgtaatag atactataga aacttcaagt gaagagtctg
    45241 tgttagtaac tgaactaagc agttttcagc ttgagagtat agatgaattt agacctaaag
    45301 taagcgcaat attaaatatt acagaggacc atttaaatag acaccatact atggaaaaat
    45361 acatagaagc aaaggcaaat atatttatga accaaactgt tgaggatttc tgtgtattaa
    45421 actatgatga tgagatagta aaatctttag ctgataaatg caatgccaaa gtaatttact
    45481 tttcaagaac taaaaaagta aatggaggag tatatttaga aaataatgac ataataatag
    45541 atatagatga taaaatcaaa tttctaaata aagatgatgt aagtttacct ggaggtcata
    45601 acttagaaaa ttgtatggca gctatagcaa tagcatatgt ctgcaaaatt gatttagaag
    45661 ttataaagga tgtacttatg acatttaaag gagtggaaca cagacaagag tttgtaagaa
    45721 atttagacaa tgtaatatat gtaaatgatt caaagggaac taatccagat tccactataa
    45781 aagctataca gtcttatgat agacctataa tacttatagc aggggggatg gataagggaa
    45841 gtaattttga tgaacttctt gaaactgcaa agtcatatgt taaatcattg gtcttattag
    45901 gagaaactgc atcaaatata gaaaattgtg ctaaaaataa aggatttaat gacatacata
    45961 tagtaaaaga tatggaagaa gcagttaaga cttcttatga aatttcaaaa agtggagata
    46021 tagtgcttct ttcaccagct tgtgcaagtt gggatatgta tgaaagtttt gaagtaagag
    46081 gaaaagactt caaagataat gtaaacaatt taaaataatc tcttacctct aaacttactt
    46141 aaatggaaga atggaggtag attagttgga tgcctaaaga aaatttgaaa aaacaaattg
    46201 acataaggat gaagactgaa tttgatggag tagtgtttta cactactatg cttttagtat
    46261 ttgtaggaat agttatggtg tttagtgcaa gttttataca atcttcattt aaacacaatg
    46321 atgcgtacta ttttctaaaa aagaatgtaa tatatgctgt acttggattt atagttatga
    46381 ttattacatc aagaatagat tatagttttt ggaagaaaaa tgctacagca attggagcta
    46441 tagcagtagt attattattg ttagttttga cccctttagg gatagaagca aacggagcaa
    46501 aaagatggtt gggaatagga gctttaacat ttcaacctgc agaaatcgca aagtttgcta
    46561 caataatatt aactgcaaaa ttaattgaaa aaaattatga taaaataaaa tctttgacaa
    46621 aaggtgttgt accacttctc gtagttccag ggatattttt tgcgttgata atacttcagc
    46681 caaatttgtc aacagcaggt actgtaattc tagttacttt tgtaatgata tttgttgctg
    46741 gaatggatat gaaaattgta tttgctatga tagggagtgg ggctgcttta tttgctgcat
    46801 tagtaattgc tgaaccctat agacttagtc gtgttacatc atttttagac ccttttcaag
    46861 accctcttgg taaggggtat caggtaatac aaggtctata tgcactaggt tcaggtggat
    46921 tgtttggtct aggcttagga aagagtaaac aaaagtattt ttatatacca gagccacaaa
    46981 atgactttat atttgctata ataggagaag agttaggatt gattggttgt ataatagtta
    47041 ttatgctatt tgtagtttta gtctacagat gtgtaagaat agctttgaag acttctaatg
    47101 tatttgcttg tatggttgtt ataggtatag gtgcacaaat tggaatacaa gcagctttaa
    47161 atatagcagt tgcgacatca tcaatgccag ctacaggtgt agcactacca tttataagtt
    47221 atggaggaac ttcactcacc atctttatgg gagctgtagg aatagtgtta aacatctcaa
    47281 agcatgtcaa aattaattaa caggagatga tgatttgatg aaagttttat tatcaggcgg
    47341 tggaactgga gggcacgtgt atccagctat agctattgca aacaaaataa gagatgagca
    47401 tccagacgct gagataattt ttgttgggac ggaaaaggga atagagtcag aaatagttcc
    47461 taagtatgga tttgaattaa agactgtaac agttcaaggc tttaagcgaa aaatagattt
    47521 cgataatgta aaaagagttt ttaagctttt taaaggtttg gagcaatcaa gaaagattgt
    47581 taagaaattt aaaccagata tagttatagg aactggtgga tatgttagtg gacctgtttt
    47641 atttaatgca tctatgggga aaataccagc cataatacat gagcaaaatt cttttcctgg
    47701 tgtaactaat aagattttat ctaaaacagt tacaaaggta cttacaagtt ttgaagattc
    47761 gcataaaaga tttccagagg cagcagaaga taaattagtt tttacaggaa atccagttag
    47821 aaaagaaatt ttattatcaa gaaaaaatat tgcaagaaag aatctatcaa taagtgacga
    47881 aaaaagaatg gtactttgct atggtggtag tggaggttca agaaaaataa atgatgcaat
    47941 gagacttgta ataaagaata tggtaaatga agatatagct tttatatttg ctacaggcaa
    48001 aagctattat gatgaattta tgggaagtat tagcgatata aatcttaaac cataccaaaa
    48061 agttgtgcct tacttagaag atatggcaaa tgcacttgca gcaagtgatt tggttatagg
    48121 tagcgcagga gcaatttcat tagctgagat aacggctctt ggaaagccat ctataataat
    48181 acctaaagct tatactgctg aaaatcatca agagtataat gccaagagta tagaaaaaca
    48241 aggggcagga attgctattt tagaaaaaaa tctaactcca gagagcctaa atacagcagt
    48301 atttaaactt ttaggagata gagaactttt ggttgatatg gcaaatgcaa gtaaaactat
    48361 aggtaagcct gaagccatag accttatata tgatgagata atgaaagtat acaattcaac
    48421 acaaaagtca acttctaaaa aaacaaaaaa agaaaaagtt attaaggaag taaaagaaat
    48481 aaaaaaagaa acgactccaa gtatagaagg tcaagctaag gtaataggaa taaagaaaag
    48541 ataagtaaat atttacccct aatttataat atattagatt ttctaaatta ttataaatta
    48601 ggggtttatt tgtatgtata cagatttaaa tatataaata gtatgtagta tgctatgttt
    48661 attttgatga aatattgatt tatttataaa atttaatacc ttatttggat gttatgtaat
    48721 aaaatgcaaa aatttgactt taaatattat aatttttttg taggaaaaac aagctctaaa
    48781 ggtgtattta ttaaccaaag gggttgatta tatttgaaaa aaagaagaaa gttaaatacg
    48841 aataatgtca tgatagtttt agtttttata cttatgttat ctttttgtat atgtataatt
    48901 gtaaaaagtg atttatttga tgtaaagaaa atagatgtaa ttggaaataa gagggtgacc
    48961 aaatcaaata taatgaaaga actaaatgta aatctaaatg aaaatatttt tgcatacaat
    49021 tttaaagata tgaaaaataa acttataaaa aatccatata tagaaaatgt ggaaataaaa
    49081 agaaaacttc ccaataagat aattataagt ttaaaagaaa aagaaatatt tgcagtatta
    49141 aaagatgaag ataattattg ttatatagat aaaaaaggaa atttattgga agaactaaga
    49201 ggttctaatg aaagtaaaaa agacttgata gtagatgtag attatagcat tgatgataat
    49261 aaatctataa aatttaaaaa ttataaaact aaggagaatg tatttaaaac tttaaattat
    49321 ttaaaagaag aaggaattta tagaaaaata aattatgtaa acttaaaaaa agaaagcaat
    49381 atagaaatgc ttacaagaag taatataaaa atcttacttt ctaatgatga taacttagat
    49441 tataatatat ctagggtaag taaaattctg attgacctgc aaaataaaaa tactaatgga
    49501 gggactataa atcttaacta tggaaagttg gcagtgtata gtccagaagg atagacaatt
    49561 gtaaggaagt gatatattga aaaaaagatt tataaataaa agtataatca taggaagtat
    49621 tgtattgggt gttcttgtta gtttacaact taaaattatt aatatagaaa atagagggat
    49681 gacaactttt aaaagaggag agcaacttac agaagaactt aaatctttaa aaaaagaaaa
    49741 agagaatcta caatcagaag ttaatagtgt gaagaaagat atagagattt atagaggcaa
    49801 aaacaatgaa ggagaacaag acatacttaa gtcagaaata gaaaaatatg aaacattagc
    49861 tggatataca gatgttgaag gaacaggcat aaaaattgag ataaattcta caaaagactt
    49921 aggaaactct gataaaaatg atagtatact atataattat gatttattat tatcaatgat
    49981 aaataaatta aattcagcac aagcaagtgc catatctata aacgaccaga gaatagtttc
    50041 taatacatat atgtatttaa aagaagacaa gctttatatg aatgacactg tcataaaaga
    50101 accaattata ataaaagcaa ttggtgattc tgatacattg gcttcggcac ttaatataaa
    50161 gtatggtatt gtctgggaaa tagaaacata ttataatgcc aaagtaaaag tgaccaaaga
    50221 agacaatata gaaataaatg gtcatagtga tataaacaaa gcagagggga aataatagta
    50281 tgaaaaagaa aatagttata ttaggagcat tcatattagg cgttttcata tcaacttata
    50341 taaaatcact agacccaaat agagtataca taacattagg tcaaactgaa agtattgaaa
    50401 gtgaggtaga aaatacaaaa aaagaaataa aaaacttaaa agaaactctt aaaaagaaca
    50461 aaaaaacttt gaatgaatat aaagaagcaa aaaagaatgg aaatgaatct atccaaacac
    50521 ttatgcaaaa agagcttgaa gaagttaaag aattaagtgg ttattcaact gttacagggc
    50581 caggcataac tattactatg agggatagtg agagagagtt aaaagacgga cagaatccaa
    50641 acgatttgat tatacatgat atagatattt tgagggtttt aaatgattta aaaaaggctg
    50701 gagcaagagc aatttctata aatggagaaa gagtactagc aacaagtaag ataaaatgtt
    50761 caggagctac tattacagta aatgatacta catatggaca accatttata ataaaagcta
    50821 taggagatat agatttattg agtgcagcta taaactctcc agaatcatat gctaaatctc
    50881 ttaaggatat atatggaatt aatataaaag ttcaggaaaa taatggaaat aaagtgaatt
    50941 tatttgcaaa ataaaacgaa aaatacaaaa aaataaagaa aaagtaaaaa aaattaataa
    51001 aaaggattgt aatgtagttg tgtttcaaag taaaataaag aggtgaagat ttatgttatg
    51061 ggttttagga ggattagcat ttggtgtagt agtaggttac tatattccat ttacatattc
    51121 tatggattat tccatatata tgtcagtagc tattcttgca ataatggatt ctatttttgg
    51181 agcgataaaa tccaattttg aagataacta tgataatgta atttttatta ctggtttcat
    51241 aggtaatgct atattggcta tattattgac ttatatagga gaaaagttag gagtttctct
    51301 ttactatgtt gctgtattag tttttggtat gagattgttt aataacttat ctataattag
    51361 acgatatatt attagtaata ttatgaacaa aaaacgtaaa aattaaagag catttaatat
    51421 atacgtaaat tattttatac ttaaagagta atatttgaca atataagtaa gaaatttaaa
    51481 aaggaaaatt tacgtttttg tggaatatgt tacttaaagg ttaacaaaat aaaagaagaa
    51541 aatgatataa ttaatacata cgataacttt gaatcatgag agaagggggt ttatgatgct
    51601 aaactttgac gtagaattag aagaatgtgc acaaattaaa gtaataggtg taggtggcgg
    51661 tggaaacaat gctgtcaata gaatggtaga agctcaacta aaaggcgttg aatttatatc
    51721 agtaaataca gataaacaag ctttatatac atcaaaagct gaatataaag ttcaaatagg
    51781 agaaaaatta actagaggac ttggagcagg agcaaatcca gaagtaggga aaagagctgc
    51841 tgaggagagt aaagatgaaa tagtaaagtt acttcaagga gctgatatgg tctttgtaac
    51901 agccggaatg ggcggtggta ctggtacagg agctgctcca gtggttgcag gcttggcaaa
    51961 agaaatgggg atacttacag taggtgtagt taccaaacct tttgcatttg aaggtaagat
    52021 aagaatgaag aacgctgaag gtggaatagc agaacttaaa tcaaaagtag atactcttat
    52081 aacgatacca aatgatagac ttttacagat agtacaaaaa aatacatcaa tgttagatgc
    52141 ttttgcagtt gcagatgatg tgttaaaaca aggtatacaa tcaatttcag accttatagc
    52201 agttgaaggg ttaataaact tggactttgc agatgttact actataatga aagacaaggg
    52261 acttgctcat atgggtatag gtagtgctag tggtgaaact agagcaattg atgctgcaag
    52321 acaagctatt caatctccac ttctagaaac atcaatacaa ggagctaaag gagtacttct
    52381 taatgttaca ggtggtccta acttaggatt atttgaagtt aatgaggcat caactttagt
    52441 tatggaatcc tgtgacccag aagcaaatgt tatatttgga gcttctataa aagaagattt
    52501 aggtgatgaa ataatgatta cagtaatcgc gacaggattt gaaggattac aaaatggtgc
    52561 cttagattta gatactaaac ctaaatcaag catacgttct tcattaaata caacagtaaa
    52621 acaagctgta aaagaaattg aagaagaagt aattgctgag gaaaaaatag agcctcctaa
    52681 aaaggcaagt ataattgaag aagatgatga tgagagcatg gagataccta cattcctaag
    52741 aagaagaaga taatatgtaa gcttataaag aagtcaatag acttcttttt attttgctca
    52801 atttagatag ttagtttgtg gctagactta aaaaaatttt taaatattga taaaatttaa
    52861 aaagtaagtt tttagtatga attaaatcta ataggtatag aaaaaaaata tagttatagg
    52921 agttagtata gttttttatg attagacaag agtaatctta tttgttaata ttaaatctga
    52981 attaaatgta aacatttgag gaaaaagaca aattaaagtc tgaaagggga ttaagcatga
    53041 ttaaactaaa aaaggttctt tctttagtta tggtagggat tctatcagta tcaattcttg
    53101 caggatgttc aaaaaaagaa gattctaaag gcaaagaggg taaagaaaaa ttagttgtat
    53161 ggtctgcacc attaacagac catgatgcag atgcatggaa gccgatattt gaaaaatttg
    53221 aaaaagaaaa taactgtgaa attgaatttc agatagtacc atgggataac tacgcagaaa
    53281 aatatgcaac agcaataagt gcaggtgaag gtccagatat aggatacatg tatgcagaga
    53341 tgtttcctca atttatagaa atgggtgcgg tagaagattt aacaccttat ttagaaaaat
    53401 caggaacttc agataattat ctatacttag atgatgcaaa aatgatgggt ggtatttatg
    53461 gtttacctat agaagctgct aatccaggcg tattgtacta caataaagat atactagaaa
    53521 aattaggaga aaaacctcca aaaacatggg atgattttaa aagaatctgt gaaaaagcaa
    53581 caaaagatac tgatggagat ggaaaaatcg accagtgggg tcttgcacaa ggttggggtt
    53641 ctaaagtatt tggaagctta aactggaact ggtatccgta tttatggcaa gctggtggag
    53701 atatatataa tgatgattta aaatcagtta aatttaataa tgcagaaggc ttgaaagctg
    53761 caaactttat aaatgatatg aaaaagtata ttccagaaga tgctttatca aaagatagta
    53821 atgaaatgat tgaaagtgta tttggaccag gaaaagctgc atttactata atgctatcct
    53881 ctgctgctac aagtacattt gataaatcat tcccggattt aaactgggga tatgtaacat
    53941 cattagaaga taagacagtt ggaagttttg cttcagtaga tgatttaaca ttaatgtcag
    54001 catgtaaaaa taaagaactt ggatttaaac ttcttgagta tatgctaagc aaagaatcaa
    54061 tggaagcttt ccacaaagaa atacctagag ctccagttgc taaaggtgaa aaataccaag
    54121 gagacccaag atttgaagaa atggtgacaa gagataaaca tatgtataga ccattgacag
    54181 ttggacctca tggagtagag atatatgaat atttatggaa acaacttcaa atgatgatag
    54241 ctggagacat aactccagaa caagcactaa atgaatctgc aaaatatgca aatggattac
    54301 tagcacaata atttatattt gaatttacag actatataat ttgattttat ataagtaaaa
    54361 gatttacttg atatattatt aaattatgta gtcttttttt gtaaatatac caaaagtaga
    54421 gcgaataact tctacctaga tatattggat tctacaaaaa agtctatttg tttggcatta
    54481 aaaaaatatc ttttgacgac ataaagtata agacatatat cattgttctt tttaaataga
    54541 atttgttttg gattcgacca tcaaaagtga cataaaattt tgtacatact atcttataat
    54601 atgtttaaag gttttaaggg gggatacatg gtgtatattg agtactatgt tatagaaaac
    54661 ctagtaataa attatattat tataagttgt acttctattc ttactaaaag atataatcct
    54721 aaaaaaaata agttattggg ggctagttta ggaggtgcct attctgttgc ttatttgtat
    54781 ccatcaatga atatactatt tactgtacca tttaaaataa taatcatgag tataataact
    54841 ttaatttcat ttagaagtaa gagcaaaaaa gattatgttc atgtagcgtt agttttttat
    54901 ctagtaaaca tttttatttc tggaagcact tattttataa tttattttac aggaataagt
    54961 cacttaaaaa tatctttctt aattgcatgt acttatgtga gttgtgaatt attaaaatac
    55021 atttataaag atttgaaaat gcttaagtac attaaggagc ttacaaagac tataaatata
    55081 aacttactag aaaaaagttt ttgctgtaag gctttagtag atagtggtaa tttgttaaaa
    55141 gacccaataa gtcaaagtga tgtaataata gttaagtcta gtgtgttaga aggatttatt
    55201 ccagaaaaac tattaaatat taattatgaa gatatagata tgaagaaagc acaagaaatt
    55261 ataggaagtt tagatgataa aacttcaggt agagttagaa taatacctta taaacatgct
    55321 ggaagtaata agacaagcat aataataggc ttaaaagctg actatataga agtagatgag
    55381 caaaagatag gaaatataat acttggtatt tcaaatttta atgatagaga atatggagca
    55441 ataatgaatc caaatatatt gcctggattt taggtgaaaa tttaaggggg acaaggaatg
    55501 ttacgattga aagaaagaat aataagcttt attactatgt taggtattaa attaaaaata
    55561 ataaagccaa agggaatata ctatatggga ggggcaaata tacttcctcc tccattgaaa
    55621 ccagaagaag aaatggagct tttacaaaag ctagaaacag atgaaagtgt aaagtcaatt
    55681 ttaatagaaa gaaatcttag attagtagtc tacatatcga gaaaatttga aaatacaggt
    55741 atagatgtag aagatttgat ttcaatagga actataggtt tgataaaagc agttaatact
    55801 tttaaactga ataaaaatat aaaattggca acttatgctt cgagatgtat agaaaatgaa
    55861 atattaatgt acttaagaaa aaataataaa aagaaaacag aagtatcatt tgatgaacct
    55921 ttaaatatag atttagatgg aaacgaactt ttattatctg atgtattggg tacagaaaat
    55981 gatgaaatat acaaaataat tgaagaagaa atagatagag atttgttggt tatggcactt
    56041 gacagattaa gtgacagaga aaagcaaatt atggaattaa gatttggtct tattgataaa
    56101 ggtattgaaa aaacacaaaa agaagttgct ggaatgcttg gaatatcaca gtcctacata
    56161 tctagacttg aaaagaaaat aatctcaagg ttgcaaaaag aaatgaaaaa atttgtataa
    56221 tgctaaatta attcttctta aaaagtataa aaaaattgga aatgtaaata atttcaatag
    56281 atgaatactt ttgagagagg actgaaaata tatgcaagtt aataaggttg aaatatgtgg
    56341 tgttaataca tcagaacttc cagttcttaa aaataagcaa atgaaggaac ttttattaca
    56401 aataaaaaat ggtgatgaag aagccagaca acagtttgta agagggaatt taagattagt
    56461 cttgagtgta ataaaaaagt ttaacaacag aggagaaaat atagacgatt tatttcaaat
    56521 aggttgtatt ggtcttataa aagcgataga taactttgat ttaagccaaa atgtaaggtt
    56581 ttcaacttat gctgttccta tgattatagg agaaattaga aggtatctaa gagacaataa
    56641 cccaattaga gtaagtaggt cattaaaaga tatagcatat aaggcactac aagttagaga
    56701 aagattaatt agaacaaatt ctaaagaacc tacagtatca gaaatagcaa aggaattaga
    56761 attagaagta gaatcagttg taatggcact tgatgccata caagacccaa tatctctgtt
    56821 tgacccagta tatcaagaca atggagatgc aatattcgtt atggatcagg ttcaagataa
    56881 aaaagatact gatgaaaatt ggttgcaaga aatatcactt aaagaagcta ttaagaaatt
    56941 aaatagtaga gaaaagttgg tattagattt aaggttttac aaaggaagaa ctcagataga
    57001 agttgctgat gaaatcggta tatctcaagc acaagtatca agaattgaaa aaaatgcttt
    57061 aaagaatatg agaaaatatg tataagtaat ccatggactg taaacattat tttaatttaa
    57121 atgacctata taggtcattt ttttttactt cgatacatat ttatttttaa agaaagggtg
    57181 agtacaatat gattagagtt tctgatataa tggaaaaaga aattataaat gtaaaaaatg
    57241 gaaaaaggat ggggtttata atagacatag acatggatat tcacgaaggt aaggtagtct
    57301 catttaccat ttttggagat ggaagtagaa gttttttttc aagaggaggg gatgaagaag
    57361 ttatattttg gaatgatata cttaaaatag gttgtgatac aataatagta aatataggtt
    57421 cagaattaag cttagatgag tttgagatat agttaaacaa aggaggaata tagatgcaat
    57481 gtccttattg taattataaa gaatcaaagg taatagattc tagacataca gatttaaaat
    57541 ctatcagaag aagacgtgag tgtgaatcat gtaaaaagag gtttactacg tatgagaaaa
    57601 tagaaacaac tcctttaatg gtcattaaaa aggataatag tagagaatat tttgatagag
    57661 aaaagataaa atatggattg ctaaaagcat gtgaaaaaag acctgtttct attgacgaga
    57721 ttgaaagtat tgttgtacat attgaaaatg aaataaataa atgttttata gaagaaattg
    57781 aaaccaaaaa aatcggtgag atggtaatgg ataaattgaa agagttagat gaggttgcct
    57841 atgtaagatt tgcttctgtg tatagacaat ttaaagatat aaatactttt gtaaatgaac
    57901 ttaaaagtat actgatagaa aaaggagaca aatgatgaaa gattatataa atataaaaaa
    57961 tgtacaagat attaaagagt atgttaattt aagtggtaat tgtgaagaac ttgatgaaaa
    58021 attaaattct gtaaatctag ttataacatg taagaatata gatgcaaaaa atagagaaga
    58081 tatgttaaaa gtatgtaaag aatgtgattt gacatttgaa aatctaacta gtaattctca
    58141 aatacattca gatatagtta atatagtcaa taaagatact atagggaaaa gaagagatgg
    58201 agatgcactt ataacaaact tggaaaaagt accactttta ctgtttacag cagactgtgt
    58261 acctatatca attatagatg ctaaaaataa agccatagga ctggctcatg caggttggag
    58321 agggactttt agtaatatag gtcataaaac aataaaatta atgtctgaat gctataaaac
    58381 agttcctgaa gatttagtat gtataattgg gccatcaatt ggaccatgtt gttatgaagt
    58441 gtctgaagat ttagtagaaa aatttaacac aattcttaca aataatgatg aaaagttcta
    58501 tataataaaa gagggaagtt actatttaga tttatggaaa attaatgagt atatgcttag
    58561 atgtagtgga gttaaaaaag aaaatataat aaatttaaat ttatgcacta gttgtagagc
    58621 agataaattc cactcttata gaaaacataa taaggcatca gaacgaatag gaacggtact
    58681 acagataaaa tagagaggag ctttttaatg aatactaaag tgcttgttat agacgatgaa
    58741 atgcatatag ttgagctatt aaaattcaat ttggaggtgt caaattacga agttagttat
    58801 tcatatgatg gatttgacgg atttataaag gctaaggaaa ttaaaccaga tttaatactt
    58861 ttagattgga tgttaccaaa tataagtgga atagaagttt tgagaaaaat aagaagtgat
    58921 aaggacttaa aaaatattcc tgttataatg cttactgcta aaaatatgga aaatgacaag
    58981 gttgaagggc ttgaaatagg tgctgatgac tatataacta agccatttag tataaaagag
    59041 ttgttagcta ggattagttc tgttttaagg agatataatt tgactagctt aggtgaagaa
    59101 aacaatatac ttactacagg taatttaaaa ctagatttat caaaacatga agttaccaaa
    59161 ggctctgaaa agatagagtt aactcttaag gaatttgaat tgttaaaatt attaattcaa
    59221 aataaaggaa aagtactttc aagaaattat cttttggata aaatatgggg gtatgaatac
    59281 tatggagaaa ctagaacagt agatgttcat ataagatatt taagaaaaaa aatagaagat
    59341 gaagataaat cggaaaaata tatagagact ataagaggtg taggatacaa aatagattaa
    59401 aaaggttata ttttaggagt gttatcttgt ggaagattta aatagtatat atttttttat
    59461 tgttatgttg tccatagcca ttgttatatt agctgtaaga tacacaataa cattaaggaa
    59521 atatttaaaa gagtttatat acgtctcaaa aaaagtaagt aataatgaat atcatgctag
    59581 gcttaacata tcagccaaag gagaacttgg cgaattagct agaaatttta atcatatgat
    59641 aaagaatatg gataaaacct tagaagaagt acagtataaa catttacagc taaggtctat
    59701 attaaagagt atatctcatg gaattttagc tatagatgta aatggaaata tacttctgat
    59761 aaatgatgaa gcaaaagaaa tgataaagag tgaaccaaat caattagttg aaggtcataa
    59821 tattaatgtt gtaataaaag aagaagaaat attaaaacaa atacttcaat ttattggttc
    59881 taaagataat gaaactgcta atattactac taaagatgat atcgtatata agataaaagt
    59941 agacccagtt tatcttcaga atactaacaa cgtaataata ggttcgatag taaatataga
    60001 agatattact aaaaaagtta aacttgaaaa tatgagaagt gattttgttg caaatgtaag
    60061 tcatgaactt aaaacaccac ttacatctat aagtgggttt gttgaaacac taaagtcaaa
    60121 tgaaaatata gatgtgaata ctagaaatag attcttagaa ataatagaaa gcgaatcaga
    60181 tagattaaaa aggttgattg atgatatatt gctgttatca tttgtagaaa ataaagatac
    60241 tcttcttatg gaaaatgttg tagtatatga tgtatttaaa gaggtatatg aaataactca
    60301 acattcagct agtgaaaaaa atatagaagt tttatataaa tgtgatgata aatcaataag
    60361 tatactatcc aataaagact atataaagca agtgttctta aacctagttg ataatgctat
    60421 aaagtatacc caagataatg ggattgtaca agttgtagtg ttaaaagatg aagaaaaaat
    60481 cgtaattaaa gttatagaca atggtgtagg gataccaaaa gaagatgtag aacgcatatt
    60541 tgaacgattt tatagggtag ataaagcaag aagtagggat gtaggaggaa cgggtttagg
    60601 attggctata acaaagcata tagtcaaatc actaaatgga tgtataaaag taaaaagtga
    60661 acttggcatt ggtagcgaat ttatagttac aatattacaa aaaaatttcc ttaaatagaa
    60721 gggaattttt tttgtttttt gcacaaacta tataagagaa ggagctgaga aaatggaaga
    60781 aagtttattg aatgcaaatt tatttagaca ctcttttata gttgcattag ttgtaggaat
    60841 attatgtaga ggattagttt taagagttac agacaaacaa tacccatcaa gaccacaaga
    60901 ttatttagaa cagataatta tatctgggct ttcagcttcg ttaggtgcta tagcattacc
    60961 tgcacttata gataaggagt ttgcagcctt gacatttttt gcagtagcaa tacaacagtt
    61021 tcaaggtctt gcagaacaag aaagaataac actaaagaat atcgataatg aagaattagt
    61081 accaaaagga gacgcttacg ttgaagaaat agcatctacg tatgaatcta gaagttatat
    61141 aagtcttttt tctgcactgg tatcttcgat agtttatatc gtttttgcaa gaaagtatgg
    61201 ccttagcttt ttttattgca caatcctagc tattgtgtca ggagctattg ttggtttgat
    61261 ttttagaaga tttttaagaa ggaacagtat agcagatata gcagatatag ttcctgcaaa
    61321 aataagtttt gaaggaccta ttttaatggt aaatggtgta ataataacta acataggtct
    61381 agaaagtaca agagaaaagt atagaaatga atgtctggcc atagaagtta taccaagaga
    61441 tttaggtgca tttggaatag taaatgatat agggcaaaga caagctataa tacataatct
    61501 atttattcat atggggatag atagagatgt agatgaggtt gatattgttg ctatatctaa
    61561 gaccaattta gaaaaaagta ctgtggttat accatatatg ccaatactca aagatataga
    61621 tgtcatgata gatgtagtga aaagtacacc tatcatagaa acatcaaaag gaaagcagag
    61681 tgatttttct agaaagactt tgtagattta catgtaaaat ttcaaattaa atattttagg
    61741 agtgatttaa tggatagagt attttttgtt gctgttatta ttggtataac atctagaatt
    61801 ataatgttga atttagacca aaaacagtat ccaacgcaac caaatgtttt actatctcaa
    61861 cttatattag cattcgtcgc ttcttcatta ggagcattat tggttccagc tcttataaat
    61921 cgttcttata catctataac ttttttatcc ctagcagcag agcaatttag acaagtgaga
    61981 gcaaatagaa gaaatacatt gcaaaactta gaggaagttc aacttgtaaa gagaggagct
    62041 gcattcatag aagagatagc tagaacctat gaagtaagaa attatatgtg tatagttaca
    62101 tcttttttaa caataggatt gtattatgta atacttgcag aaacgaaaat aagtgaagga
    62161 atgagtttgg taataagttc aatttgtgga ttagtgttag cctttatatt aaaaaaactt
    62221 cttactagaa aaagtattgg agacatagct gatgtaatgc ctgctgagat tagttttgta
    62281 gatgagtcta tattgaaggt aggagattta aagggaataa caaatatagg tctaaaaagt
    62341 gatagagaag tatatattaa tagaggtgta ggaatacaaa taattcctaa aaataaagat
    62401 tatgctaatg cagggatatt atttgactca ggtcaaagac aggcaatagt atacaatata
    62461 tattcaaggt taggtttata tggagattat ggagaacctt cattcgtacc attacctaga
    62521 aggaataaag aggatgaaag tataatgatt gcttatttac cagtagataa gaatgtggaa
    62581 aaagtaatgg aagccgtaaa gtcatgccca atactttcaa gttctaaagg aaaaaactta
    62641 tcactaaaaa attataaaat aggaaagaaa ggaagtgcat aagatgggaa tggatatagg
    62701 tttaaatgaa tataccctag ctatagttac acttgataag aatatgaaaa atggtggagg
    62761 ttgtccaata ttttatgcaa atgatgagaa agacttacaa aataaggcat tgttgatgtc
    62821 aaagtgtgta ggtggaatgg ttcatgatat gacaaatggg acgttaatca tagtaaaaca
    62881 ttaaatttat aaaatttttt taagaacaaa taatattcaa atttttaaga aacttaaatt
    62941 tgaatattat ttgttctaat ctattttata gctatttact tatattgact attagaatta
    63001 aaatgtgtta ttatgacatg aaatgcttaa aaatgctatc ataaaatata ataaataaat
    63061 aaattgcata ttaaaatata ttataataag cattgatgaa tacaaaagag tggtgaaaat
    63121 attggaagta aatgtaaaaa aagtaaataa tattataagt aaggtttata aagatagtat
    63181 tgcagaagaa ataggtatag aggtaggaga tttacttata tctgtgaatg aacagccaat
    63241 acatgatata atagagtata gattcttact aagtgatgaa tatttagatg tagaaataca
    63301 aaaaaaagat ggcgaagtct acatatacga gatagaaaaa gactatgatg aagatttggg
    63361 tgttgaattt acaaatccga taattgacca agctaaaagc tgtagaaata agtgtatgtt
    63421 ttgttttata gaccaattgc cagaaggtat gagagaaact ctttatttta aagatgatga
    63481 ttcgagatta tcttttttac aaggaaattt tgtcacactt acaaatatga gtgaagaaga
    63541 tataaataat attataaaat atagaataag tcctataaat atatctgtgc atacaactaa
    63601 tccagagtta agacaaaaaa tgataagcaa taaatttgca ggaaaattat atggtataat
    63661 gaagagattg gcagatactc atatagaaat gaactgtcaa attgttttat gtccaggtat
    63721 aaatgatgga aaggaattgg atagaacaat aaaagaacta gctcaacttt atccgtatgt
    63781 aaacagtgtt gcgatagttc cagttgggat tacaaagcat agagaaaatc tagtagaatt
    63841 aaatatattt aatgataaga gcgcaagtaa aactatagag caaatacatc aaatacaaca
    63901 gaaatatctt gaaaaattag gtactcgatt tgcattttta tcagatgaat tttatatact
    63961 atctaatagt gaattgcctg gatatgaaga atatgaaggt tttttacagt ttgaagatgg
    64021 tgtaggtatg atacgtaagt taaaaacaga gattgaagag tatctaaata tattgcctga
    64081 gaagattcta aaaagagaga agaaagtatc aatagctact ggtcattctg catatgaatt
    64141 tatacagagt atggcagatg ctatgatgga caagtttaaa aatcttcaag taaatgtata
    64201 tgaaatcaaa aacaagtttt ttggagagac aataactgta tcaggtcttt taacagctaa
    64261 ggatttaaaa gaacaacttg aagataaaga attaggagaa gctctttata taacaagaag
    64321 tatgctaaaa gcagatgaag aaattttctt agataatatt gaattaaatc aattagaaga
    64381 acttatgaga ataaaaatta tcccttgttt gaatgaagga aaagattttg tggataaaat
    64441 tttaaaatag aaaacaaaag atggaaggag aaataaaatg agtataagta ggccagttgt
    64501 agctgtagtt gggagaccaa acgttggtaa gtctacaata tttaataaat ttgcaggaaa
    64561 aaggatatca atagttgaaa atacacctgg agttacaaga gatagaatat ttgctgaagt
    64621 agaatggtta gataaatatt ttacattagt ggatacagga ggaattgaac ctgatagcga
    64681 agatataata ttatctcaaa tgagaaatca agccatgctt gcaatggaca tgtcacatgt
    64741 aatacttttt atagttgatg gtaaagctgg aataacagct gctgataaag aaattgcaca
    64801 attgcttaga aagacaaaaa aaccagtaat cttagtggtt aataagattg atagtcaaag
    64861 tcaatttgat aatatatacg atttttatga gttgggattt ggaacgcctt ttgcagtttc
    64921 aggagccaat agtatgggat ttggagattt attagatgag atagttgaaa attttccagc
    64981 aggattagat acagagtatg aagaagatat aataagagta gctataacag gtaaaccaaa
    65041 tgcaggaaaa agttctatac tcaataagat acttggagaa gaaagagtaa ttgtaagtcc
    65101 aattgcagga actactagag acgcaattga tacttatttt gaaaaaaatg gacagaaatt
    65161 tcttctaata gatacagcag ggcttagaag aaaaagtaaa atatatgaga caatagaaaa
    65221 atacagtgta ataagagcta tgagtgctgt agatagagca gatgtagtat tgatagtaat
    65281 agatgcctta gaaggtgtaa cagaacaaga tacaaaggtt gcaggtatag cacatgatga
    65341 aggaaaagga tgcatatttg taatcaataa atgggattta atagagaaag ataataagac
    65401 tatgagtaat tacacaaaag atataaaaga aaaatttcca tttatgatgt atgctccaat
    65461 cgtatttgtt tctgcaaaaa ctaatcaaag aatgaacaag atactagata cagttgaata
    65521 tgtgtcaaat gaacattcta agagaatatc aacttcagca ctgaatgaag taattggaga
    65581 agctgtaatg ttaaatcaac caccatctga caaaggtaga agattaaaaa tttactatgg
    65641 gactcaaact gacattagac ctcctaaaat tacattgttt ataaatgata aggatttaac
    65701 tcacttctca tatcaaagat accttgagaa taagataaga gaaaattttg gatttgaagg
    65761 aacttccata aagtttgagt atagacaaaa aaataaaaaa taaatatctt aaaatataac
    65821 taaagggggg aaattcagtg gagatattta gttatataat tattgctgta gttgcatatc
    65881 ttttaggaaa tatatctacc tcatacatag ttgcaaagcg aattgctggg gttgatataa
    65941 ggactcaagg ttctggtaat gcaggttcga caaatgtact taggacactt ggaaaaagag
    66001 caggagcaat gacattttta ggtgatgttc ttaaaggtgt aatggctgtt ttaatatcag
    66061 aatttgcagc aagattggtt ggaatagata ctcttttagc tggatatctg gcagttatat
    66121 gtgttgtagc aggtcataat tggccagcgg ttttaggatt tagaggaggc aaaggtgttg
    66181 caacttcact aggggcaatg ctagctgtaa atccagtaat aacactaatg tgtctagcag
    66241 tatttatatt ggtggtagct ataacaaagt atgtttcatt gggttctgtt gtaggaatag
    66301 gatgttcacc aatatttatg attatggtaa aaaataaagc tggtttaata gtagctctgt
    66361 tcttaactgc atcagtaata tataatcaca gagcaaatat aaagcgatta ttaaatggga
    66421 cagagagaaa aattggtcaa aagaaagaat agtaaatata ttatactcag gtggtgttaa
    66481 acatggagaa agtatgtgta ttaggtactg gaagctgggg aagtgcatta gctttagggc
    66541 ttgcaaaaaa aggtaatgat gtgagcatgt ggactcgaaa agaggaacaa gctaaaaaaa
    66601 taaacagaac taaagaaaat acagactatt taccaggagt attatttcca aataatataa
    66661 ctataagtac tgatatagaa aaaactataa aagattgtaa ggtaatagtt ttagcagttc
    66721 catcacaggc tgtaagaagt acttgccaaa aaataaaacc atttataaaa gaaggacaag
    66781 ttattgttaa tgtagctaaa ggtcttgaaa aagggactgg gcttagatta tcacaagtct
    66841 gtgaagaaga attaccacaa aatccatatg taatactatc tgggccatct catgctgaag
    66901 aagtagcaag ggatattcct actaccgtag tagttgcttc taaagattta aaaatagcac
    66961 agatgataca agatttgttt atgagcccta aacttagagt ttatacgaat ccagacatag
    67021 ttggagtaga acttggagga gcattaaaaa atattatagc atttggagct gggatatgtg
    67081 acggattagg gtatggtgat aatgcaaaag ctgcccttat gacaagaggt attagtgaaa
    67141 tgagcagact tggaattgct atgggagcta atatgtctac ctttgcaggt ctttcaggta
    67201 ttggagattt aatagttact tgtacaagta tgcatagtag aaatagaaga gctggtatac
    67261 tcataggtaa agggatgagt ttagaagata ctttaaaaga agtaaagatg gttgtagaag
    67321 gcataactgc tactgaagta gcacatgatg ttgctgaaaa attagatata gatatgccta
    67381 taactaatgc tatatattct gtaataaaga aaggttcaaa tcctaaagaa gttggaatag
    67441 aactaatgat gagaagtaaa aagcatgaaa tggaagaagt agttttaggt gatgatatat
    67501 aaactattgt ataataaata ataaatttat tttaggggtg tctcaaaatg aactttttag
    67561 tttacgaggc actcattttt atatgaaatt aaatatattt ttattatttc aacaataaaa
    67621 aaggcttatc tctattttga gacagccata ttttaatttt atttagcatg ttttattatg
    67681 tattcaatag aagaaatcat tttcatagtt aattcatcat catcagaatt ttttcctgtg
    67741 ttctttttta agaataatag attttgataa aaagaaataa ttatatcatt gattatgtct
    67801 aaatctttag ctggtatata tccagtatct acaagattgt ttaatagtat cttatttctt
    67861 tcctttatac tttctcctgt aatcattaaa gatatgtcac tatcatgaat acctaaatct
    67921 tctggaaaca tatcataata ttgttttgtt atatagctaa gttcatcact agacaagtta
    67981 aaaaatacct ggtaaaaagc ttgagcatta tcaaaagaat gcttacaaaa taatttccac
    68041 ataattatat atttcttata ttcatcattg acattttcta tacatcttga aatattcaag
    68101 ttataatctt taaaatattt tatagatgca aatgatatta aatggtctaa atttttaaag
    68161 tatttatata gagttgaact attatagcca gccatatctg caaccttacg aagtgtaata
    68221 ttttctatac cttcgttttc cataatattt tgagcagctt ctatgaaata catcaatatc
    68281 cttttctttt gtaattcttt atttgtcatt ttattcacct acaaataatc aatatagttt
    68341 atataatcgt gattttatca ttaaacttac cataaatcaa gaataatatt acaaaataca
    68401 atgtatactc gttatatttt agataattta aaatcactag aatataaaaa attttttaaa
    68461 ataaaatcat gattgacaaa ataatcatga ttatgataaa ataatcacaa ataaaattaa
    68521 tttacataca aatacgacaa gtactaaaaa tattaagaat tttaaaataa tatattcatc
    68581 cttgttgtat tgaataaatt atctgaatat taagaaagag gtgcattatg tcaaataata
    68641 tgagactaga aagattgaga aagtacatga atgaaaaaag cattgaaatt gctttaatat
    68701 ttgaaccaga caatcaattt tatattagtg gatttaaagc aataacttat tctagaccaa
    68761 ttgtaacagt agtaactcaa gataaaatag aattaatagt acctggatta gaagaattac
    68821 atgctaaaga agttgcaaaa gttgataatg tatatgtgta ttatgaaata ccagaaatga
    68881 aagaacatgg aatatcacat aaacattact tagatataat tttaaataaa taccctaaag
    68941 gaacaactgt tggaatagaa aaagatatag tatctgcaag cttttcagag tatataactg
    69001 ataagtcatt tgctatcaaa gatgttggaa gtaaaatatt tgaaatgaga tatgtaaaag
    69061 atgcaaaaga aatagaattt ttgaagatag caggttacct atctgatata ggaataaaag
    69121 ggtctttaga aaatgttaga gttgggatga gtgaattgga gtttgacgtt gaaggggata
    69181 atgctttact aaaatatgtt tctgaaaatt atcctgatac atatatagga tttgcaaact
    69241 ggacttgttc agggattgat agaacagcac aacctcattt agattctaat actagaatac
    69301 ttcaaagagg agatatagta atacatagta gacaggtttg gtatgaaaac tatagagcag
    69361 aaaatgaaag aacttttatt ataggcaaac caacagaaag acaaaaagaa gtgtttaaga
    69421 ttgcagtaga ggctcaacaa gctggattag atacaataaa agctggtata ccagcaagaa
    69481 tggtggatga agcagcaaga gctgttgttg caaagtatgg tctagagtta tattcaaatc
    69541 atagaattgg tcatggttta ggtttgtcag aacatgaaga gccatattta agatttgaca
    69601 atgaattaat attagaagaa ggaatggtat tttctatgga accagggata tatatacctg
    69661 gagttggagg atttagacac tcagatacag caatagtagg taagaatggt gctacaatta
    69721 taactaatta tccaagaagt gttgaagaac ttatacttga tatttaaatc aatacatagt
    69781 gtatgagttt gaataaattt gaaattggag gaattacagt gaaaaagaaa attggatttt
    69841 gggatttagt atttatgaat atatcagcac tatttgggat tagatggata gctaaatcta
    69901 ctgcctctag ttttggattg ggtcttggtt ctataccagt ttggttattg tttgctttta
    69961 tattctttgt tcctgcatca cttatatgtg cagagttggc tgcaacatat ccaaaagatg
    70021 gtggacttgg agaatgggtt aaacaagctt atggagagaa gtggggattt atggtgtcat
    70081 ggctaaattg gacatcaaag atattttggt attcttcttt cttgacattt ttagctataa
    70141 atattgcata tatgcttgga aatccagatt tatcaaacaa taagatgttt attttagcac
    70201 tttcactcat aatattttgg ctgttgtcct tagtaagtac tcgtgggatg gcatttggaa
    70261 aattttttac gaatacagga gcattaggtt ctacaattcc tgctatatta cttatagtga
    70321 tggcatttat gtctgtagtt attctcaaaa aagctccatc agcatcgata tatacaatcc
    70381 aaaatataat accaaaaata gatgccaatt cattagtttc tatatctgct ataatatttg
    70441 cattatcagg agctgaaacg actgctaatt tcataaccga aatggataat gctaagaaaa
    70501 actttcctaa agctatatta actgtggctg ttttaatagg aggaatctat atcttaggtt
    70561 cagtagcaat aacaatgata cttcctccag ataaaattgc agcatctaca gggatactag
    70621 atgcattagc taaagttgca caagatttag gtataggaag ttggtttata agaatagtag
    70681 catttggaat aactttatca gtactaggag cattaatact ttatatagca ggtccagtaa
    70741 agatgctttt tggaaatgta agagaaggtg tatttcctaa gcaattgact gttacaaata
    70801 aatacaatat accatcaaat gcagtaatag ttcaggctat aatagtgagt ctacttcttg
    70861 taggaacaaa cttattacca tcagtagata atatatacaa tgttcttgtt actatgacag
    70921 cattaacagc attatttcca tatgtcttgc tttttacatc ttatattaga cttagaaaga
    70981 caagaccaaa tgaagaaaga ccatattcaa ttgcaaaaag tgattcagtt tgtatcaata
    71041 ttgccagaat ggtacttgta gtaactgtag ttggcatact tttctcaacg gcaccagtta
    71101 tggagacttt aaaagataat ataatctatg agattgaaat gataggagga ggtctttttg
    71161 ttataataac aggtttaatg ctatggaaga actatgaaaa aaagatatct aataactctg
    71221 gacgttagta taaataaaaa tataattatt atggtgagct aaaagagttt acttttagct
    71281 cataactcac cataaattat tgatagatta acctaatata ttaataaata ttccgaaata
    71341 ttgaataaac aatacaataa gcaataatta attatcatga aaatttacag gtatttacat
    71401 aaggaggaag tatgtcagtt gaagtaaata aaccaagcat ttggaaaaat ttcaaagtct
    71461 tgataatact ctttgtagca ggagcattta tatatgcttt accatattta aagaattatt
    71521 attatgatac ttttgcacaa gcatttaatc ttacaaatac acaaatggga agcttaggaa
    71581 gtatttatgg tctacttgca atggtatcat acctttttgg tggtttttta gcagaccgta
    71641 tttcagccag aaaattgctt tcaggttctt taattattac aggaatatct ggtcttgtat
    71701 taacacttta tcctccatat attgttgtgt ttttaatcca tgccttatgg ggaataacaa
    71761 caatacttac tttttggcca gctcttgtaa aagctgttag aatgttagca tctgaaaatg
    71821 aacaaggaaa agcttttgga tttatggaaa gtggtcgtgg aattaccaat gcaattcatc
    71881 tatctctagt attgatacta tttgggtata tttcatcaaa agtaagtgat aaatctggtc
    71941 ttacagctat tatagtatta tactcggcaa taaatgtaat agttggagta ttagtatttt
    72001 tcaaattaaa ggataatgaa aaagaggtat cagcaaaatt tgataaagaa gccttttttg
    72061 cagtaataaa aatgcctcat acatggataa taacaataat aatgttttgt tcatattcag
    72121 ctaatatgtc attttattat tttacgcctt attcaactga agcatttgga gctactgtgg
    72181 tgtttgcatc tgcaatctca atattagctc agtattgtag accagtagca tcagctgctt
    72241 ctggattact tggagataaa gttggttcat caaagattat atcttatgga tttatactta
    72301 tgattgcagg tcttttaggt gtaatattta caccaacaaa atcatctatg atttatatac
    72361 tattgattgg atgtgttgca atatatgtat ctatgtatgc aattcaaggt ttacactatt
    72421 cgttacttga agaaggtaat tattcattat caatatcagg aactgctata ggaatagttg
    72481 ctacattagg atatcttcca gaagtacttt gtcctttagc agcagggaag atattggatg
    72541 catttccggg tgtaactgga tataggtact acttcatagt tcttactata gtagccataa
    72601 ttggattggt gtttacattt atatggatga acatgacaaa agaaagacgt aaagaactta
    72661 ttgagatgaa taataattca aatgaaaata ctactaaagt cagttaatat aatacactac
    72721 tatttggacc agcaatatta atttaattta cattgaaatt tacaaatttc tatatgtaaa
    72781 ttaaattaat attgctggtc tttatttttc tattttaaga atattaaccc ttaactctaa
    72841 atataattta ataagattag atgtatagga ggaataatat gaataataac atatacgaag
    72901 atatatccaa aaggactcag ggggatatat atattggagt agttggacct gtaagaacag
    72961 gaaaatcaac ttttataaga aaatttatgg aaaagttggt tatacctaat atagacaatg
    73021 aatttaaaaa ggatagaaca agagatgaga taccccaaag tggttcaggt aaaacgataa
    73081 tgacagtgga accaaaattt gtaccagcag atggtgtaga aataaaaata aaagacacag
    73141 tatctttaaa agtaagaatg gtagattgtg ttggatacat agttgaagga gctttagggc
    73201 atgaggaagg tggaaaacaa agattagtat ccactccttg gtcacaagaa gctatgacat
    73261 ttgaaaaggc agcagagata ggaactaaaa aagttataaa agaccattct acaataggga
    73321 tagttgtctt gacagatggt tcagttactg gaattgacag aaaaagctat gtagaaccag
    73381 aagagagagt tatacaagaa ttgaaaaatc ttaaaaaacc atttgcagtg gttttaaata
    73441 cgttaagtcc aaaaagtgag gaaacgagta tgcttagaag tgaattggaa gaaaagtatg
    73501 aagttccagt tcttccaatg aatgtggttg aaatggaaga agaagatata gaggaggtta
    73561 tggaagctgt attatatgat tttccactta cagaaataag aatcaactta ccaaaatggg
    73621 ttgaaggtct tgaaagaaat cattggataa aaagtagcat aataacaaca ttaaaacaaa
    73681 gtattataga tataggtaaa ataagggata tagaaggtat tatacaagga ttttctgagt
    73741 tagagttttt ggaagataca ggtgttgata atgtagagct aggagaaggt gttataaata
    73801 ttgatttaca gacaaagcaa gatttattct ataatgtcct tgaagaaaaa agtggattta
    73861 aaattgaagg agattatcaa ctgcttagtc tgataactag actatctaaa gttaaaaatg
    73921 agtatgataa aatagaaagt gctttaatag atgccaagat aaaaggatat ggagtagtag
    73981 ctccttcctt agaagaactt agtctggaag aaccagaaat aatgaaacaa ggaaaacaat
    74041 atggtatcaa gttaaaagcc aatgcaccat cacttcatat tataaaagca gatatatcta
    74101 cagaggtttc tccaatagtt ggaaatcaaa atcaaggtga agagatgata aaatatctta
    74161 tggaagtatt tgaagagcaa ccagcagatt tatgggaatc aaatatgttt ggtaaatcac
    74221 tacatgactt agtaaaagag caattacaaa gtaaattata tactatgcca gaagagataa
    74281 gagttaaaat gcaaaagact ttacaaaaaa ttgtaaatga aggaagttct aatattataa
    74341 ctattttgtt ataaaaatat agctacttat taaagtgaaa cgtctgtttg ctttagtaag
    74401 tagcttttta tttataacaa ttaataaaga tacttatata aattgacaat aattgataat
    74461 tgtggaaaaa ttatagtggg tgaagtatat gtttcgacag gattgtttca aagctaaaaa
    74521 tttctaggag tgtaagatga aaaagtatga gatatttatt tttatgagta taatagtttt
    74581 gtgttttata agttttccac ataaagtttt tggacaagag gaaaattgtc ttgaagattt
    74641 tgaaaggtgg gttcaagaaa ataaaaataa taaagaagaa atagtttata ctctttcttg
    74701 tgatatggta atagatgaag agtttagatt ttatattcct tatgacagta attttacaat
    74761 agataccaac aaatataaaa tattgataaa aaatcatggg agatttatta ttgatgataa
    74821 tgaattgaat ataataggtg aaggaggaaa agaaggagta atacatatag aaaatggtgg
    74881 aagtataagt attggtataa acaacataat tgctactgat gggacagcct tatacgttga
    74941 agaaggagga gacttacata ttaaatcatc ctacgaatct gttgaaaaaa taaaggcaaa
    75001 tggaaaagat gcaataggaa tttatactga aaatgatatt agaatactaa ataaggatat
    75061 tgaagtgaat ggagaacatg ctataggtgt ttattctaaa ggtgatgttg agatagaaga
    75121 aacttcaata aaagcatata gtagcaacaa tgaaagtggg ttactaagag ataataataa
    75181 gttggcacaa tcaattatat cagaaagtaa gaaagtttat ataattgatg attataatga
    75241 gcttatacct tctatagctg aagattctgg ctatgatatt gtgaaatgtt gtcatagggg
    75301 aattggtgta tttagtgatg aaataaaagt aagtaaagat gataaaatag aaaatataaa
    75361 atttcccaaa tatatggtat tagaaacatc tagtggtaat cgacttgata tagatgtaga
    75421 atgggatttt actgattatt atgaaaagtt ggaaaaggga gaaaatttta atataacagg
    75481 aaagtttaaa acagaaatgt taaataaaga aaaaattata ataaatgatg atgtagttcc
    75541 tattttgaat gtatctgtta tagagaaaaa accaatagac aatttggaac tggaatttca
    75601 aaatacaaaa aatggatatg tagctgtttt attttatgat atgccgtata gtgcaagtaa
    75661 ggtttttgtt gaatattcaa gcgatggaat caattggata tctgaagaac aggaggatat
    75721 tagagatcaa gctatacttt tttttgaaga ttttaagttg cgttgtttta gagtaaaagt
    75781 ggtaggagga ttaaaagaag ggtattcaaa tatagttttt aaaccaggat ttataatggg
    75841 aggcggagac aatcaagaga cgccagatga tgaacgggaa aatgatgata ttgatggtga
    75901 ccgtggagga ggaggtagag acgacccgga tagagatgag gatgataaca atcaagatgg
    75961 gaataatgga aatgaaaata atgatagtaa taacaatcaa aacaataata atgaaaataa
    76021 taataatgaa aatgataatt ctgatgagaa acaaccaaat actcctaaag atgatgtaga
    76081 atcaagtact gatagcaatg aaaataaaaa tcctcatgat atacctaaag acggtaataa
    76141 agaaaataat tctgataaag aaaaaggatt ttacaataaa aattcaatta cagaaaatga
    76201 tgataattat gatttaagct caaaatcagt atttggtacc aatgaacatt cttttcctta
    76261 tagggaaagt atttctaaca aaaatcaaga tacaaataaa aataagtcaa atataagtga
    76321 ttatgatgga ataataaata ataattataa attagaatct aaagaatata atctaaaaaa
    76381 agatattatt tttttatttt gt
//
LOCUS       DAEPKC010000006        72008 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.006, whole genome shotgun sequence.
ACCESSION   DAEPKC010000006 DAEPKC010000000
VERSION     DAEPKC010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 72008)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 72008)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..72008
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.006"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(67..546)
                     /locus_tag="KR294_000486"
     CDS             complement(67..546)
                     /locus_tag="KR294_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HBH0238603.1"
                     /translation="MSNKLIKNLLSGILQILFFLLGLVIVVGGFKSFMYLCFSGEATL
                     QGTIYGILMFILGVSYFIIIKSLIEVLGSSEYSLFVKENVKRFRIIGYLLLLNSLIEF
                     ISTFGTTGKGMRFLDLGFGFYFTVPVFVYFITSLMSFVIADGFVKAIKIKEDNDLTI"
     gene            complement(841..1545)
                     /locus_tag="KR294_000487"
     CDS             complement(841..1545)
                     /locus_tag="KR294_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="B3/4 domain-containing protein"
                     /protein_id="HBH0238604.1"
                     /translation="MKKFVIEDAFWNLFPSAKIGVVICNDIDNSIKDEDYKKIILKGE
                     EEALKYLEDSEFSNNQVIKVWREAFKKFKTKKGARSSIEALLKRVHNGNNIGTINPLV
                     DIYNFISLKYALPCGGEDIDKFIGDIRLTRAIGNEEFIPLGTDENSFPYEGEIIYKDD
                     GGAICRCWNWREAVRTMLTEDTNNAFLCIELVDESRFKEFENALNELAKIVQEKLGGN
                     CKISILDIDNKEVSVD"
     gene            complement(1899..2915)
                     /locus_tag="KR294_000488"
     CDS             complement(1899..2915)
                     /locus_tag="KR294_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase domain-containing protein"
                     /protein_id="HBH0238605.1"
                     /translation="MGYYNDNDNNKIRRKKISNNKDSNKKSKHSYTSANKKNKSPNTS
                     SSKRMSEKVDSQNLIKRDRDSFTRDNVRPLNTDYNQRERRRVEYKQREKKLKSKKRKK
                     QKRIRIVRALLSIMLVALIIFSVAGAIFTVSAIKGSPEVTKKLIRSKYISSEVVSIKQ
                     MPNDLKHAIVSIEDERFYKHKGVDVISLVRSVLNNVFTDTTQGASTIDMQVSKNLLTS
                     NDKTMKRKIRDMYNAKQMNKIMTKDEILEAYLNNMYLGKNAYGAAKGAEVYFGKKVSE
                     LNLAECAMLAGMTNNPARYIDHGEAKKRQVIVLYKMHQLGYITDKEYRIAKADDTPFK
                     SEID"
     gene            complement(3043..3549)
                     /locus_tag="KR294_000489"
     CDS             complement(3043..3549)
                     /locus_tag="KR294_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HBH0238606.1"
                     /translation="MKEYVVVDLETTGLDPYKGCEIIEIGITEIKNEQIVKNYSRLIK
                     PKGIISSFITELTHISNEMVENEEPLELVLPRFRKYIGDRTIIAHNAKFDLKFLNYYL
                     RMLDLEPINNYICTVELLKKCKSYKGKNKKLETACAYYNIENINAHRADSDTLATAKL
                     FLKIKDEY"
     gene            complement(3708..4376)
                     /locus_tag="KR294_000490"
     CDS             complement(3708..4376)
                     /locus_tag="KR294_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0238607.1"
                     /translation="MENITSYFTTILCVFICLSSVFIFTQLARVFINKKKINQKIKSR
                     NGFRYDRDFIEARREEIHIKDNNNNKNKSNNKKLKEEKVFKYDNGDLYKGEFVDGKKN
                     GFGIYIFSGKEKYEGLWKDDKMHGIGKYTYRDGSIYTGEFKYGLKNGLGKLTYPNNDI
                     YKGYFLDNKKNGKGVLYKNDGNKQAGIWEDDEQCKSLDFKDLNNNKINNVYQNRLNNN
                     KLKV"
     gene            complement(4789..5295)
                     /locus_tag="KR294_000491"
     CDS             complement(4789..5295)
                     /locus_tag="KR294_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase"
                     /protein_id="HBH0238608.1"
                     /translation="MGFREVKIEELQFNPFTKIGKEWLLITAGDSEKFNTMTASWGGV
                     GVYWGKNVVTTYIRPQRYTKEFVDSNDTFTIAFFDETYREALNICGTISGRDINKIEK
                     AGLTPYFVDDTVAFEEANMIIVCKKLYHGNMPPENFDAKENDKKWYPEKDYHTMYISE
                     IIKVLVKE"
     gene            complement(5666..6694)
                     /locus_tag="KR294_000492"
     CDS             complement(5666..6694)
                     /locus_tag="KR294_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HBH0238609.1"
                     /translation="MKRVYIDFEMNMPNSKSKRAVFNSDIIAIGAVMYDEKTKNIDKF
                     KSLIRPVSNEELYPHIQELTHISSEELKSAPSYEEVMRKFKKWLGIFSDIKGIYTFGN
                     LDLTCFNNTDMRSAKKNNHPRFVNNIRDLFVDIKEKYINCGMRCMNYISLKNLLEFVN
                     LEFSGDAHDPLNDAYNLFILDEAITNNVDIQNLLIIRDIIRPPFNDINSNLDNCFNKF
                     KESLYKKEGNYNIVDFSVEIIKTVRMYLLTIIDVNIQNLEIMKDISKKMDTIDKLKDI
                     EEGYFYLLEDVYFDMKDVLEDLMLYRMNEDEYKYEIKNIIKMFDEDLDNEKIYINKCN
                     NLNVVNKI"
     gene            complement(6742..7602)
                     /locus_tag="KR294_000493"
     CDS             complement(6742..7602)
                     /locus_tag="KR294_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiocytidine(32) synthetase TtcA"
                     /protein_id="HBH0238610.1"
                     /translation="MSELSGKGCEIIVPFEERLPVRDIEKSIIKKYRKNLWSKFMKAI
                     RDYKLVEEGDKIAVAISGGKDSILMAKMFQELKKHGQVNFDVEFIAMDPGYHANIRQL
                     LIDNCEYLNIPIHLFDSRIFEIADEIAKDYPCYMCARMRRGALYSKAEELGCNKLALG
                     HHYDDVIETTMLNLLCAGNFKTMLPKLNSTNFEGIKIIRPLYYIREEHIIRFIQNSGI
                     WPLNCACMVAAKKTGNKRYEIKDLIKSLESNFKNVEKSIFKAAENVNLDSVLGWQKDG
                     EKHSFLENFE"
     gene            7871..8080
                     /locus_tag="KR294_000494"
     CDS             7871..8080
                     /locus_tag="KR294_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat associated protein CotJA"
                     /protein_id="HBH0238611.1"
                     /translation="MENKTRDIKKNCGPSLARPYINNQIFTEMYCLSDALKFGTIFPE
                     LNLLESEMYNKELYAKPKKYRGGRR"
     gene            8080..8346
                     /locus_tag="KR294_000495"
     CDS             8080..8346
                     /locus_tag="KR294_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat protein CotJB"
                     /protein_id="HBH0238612.1"
                     /translation="MKDSSRAELMRKVQETSFACVDMNLYLDNHPDDKNAINTYNSLC
                     NQFAQARYAYENKYGPLTNFGYAPSRCPWQWADQPWPWDREFNY"
     gene            8375..8947
                     /locus_tag="KR294_000496"
     CDS             8375..8947
                     /locus_tag="KR294_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000265278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HBH0238613.1"
                     /translation="MWIYQKTIQHPVNIKTCDPRMAKFLITQFGGPNGELAASLRYLS
                     QRYTMPTGNMRALLTDIGTEELAHVELICTMVYQLTSDASPEELKAAGLGSNYAQNGY
                     GIYPTDSNGVPFDVRPIAVMSNPVTDLHEDMAAEQKALATYYQLINLTDDVDVIDVLK
                     FLGQREIIHYQRFGEALMDAYELEESQKMF"
     gene            complement(9182..10372)
                     /locus_tag="KR294_000497"
     CDS             complement(9182..10372)
                     /locus_tag="KR294_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HBH0238614.1"
                     /translation="MNFNQKRIAASIMATAIIMPTMGNLAYANESEVESVSIESRTIT
                     GNAVNFRKGPGTNHESMGKLYKGDKVEYVGKEGSWVKVKYNGNTGYVHGNYVAINSLG
                     SSNESSDTSVKSTKVVTAKGLNFRTGPSTSSSKISTLGYGTEVGYISESNGWSKISSN
                     GRVGYVSSKYLGTSVNDSTNENAENSSNDLVKGTKVVTAKSLNVRTGPGTSHSKIATL
                     SYGTEVGSISESGGWTKISYGNQTGYVSSQYLAEKGSVDTSIPSYSTNSPSQGADSVI
                     SFAKTLLGKPYVWGAEGPNSFDCSGFTQYVMKKSVGVSIPRVSRDQSKYGTYVNRGDL
                     RSGDLVFFDTQGSNNGSVSHVGIYIGNGDMIHASSGSSKKVTISNINSSYYSSRYVNA
                     RRVL"
     gene            complement(10632..11063)
                     /gene="dut"
                     /locus_tag="KR294_000498"
     CDS             complement(10632..11063)
                     /gene="dut"
                     /locus_tag="KR294_000498"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HBH0238615.1"
                     /translation="MYNLKVKKLNDDAIIPNFAHKGDAGMDLYSIEEVVIPPGETKLI
                     KTGICIELPTMTEAQVRPRSGLALKHSVTVLNTPGTIDEGYRGELKIILINHGKNDFK
                     VEKHMKIAQMIVKPIYDINIEEVKELSDSERGKGGFGSTGF"
     gene            11176..13404
                     /locus_tag="KR294_000499"
     CDS             11176..13404
                     /locus_tag="KR294_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IA DNA topoisomerase"
                     /protein_id="HBH0238616.1"
                     /translation="MKLVLAEKPSVAKTIASFLGAKTRQDGYFEGNDYIITYAVGHLV
                     SLYDMKDYDKDKYSGSWKMNNFPFVPEDKFKFKIDSSKTKQFNTVKKLLNRKDVEYVI
                     NATDNDREGELIAFLIFLLAKNKKPVKRILVNEWTPEDITRGIKNLKDEDEMRNLQAA
                     GYTRLITDWLIGINFTSVATLKYGNGKLLNIGRVILPTVKLVYDRDMEILNFVPKTYY
                     EIEGHFKAEAGEYKGKYVKGKESKFDTLEDANKIIASITSETGKILDKKVTMSKEYAP
                     KLFSLTSLQGYITSKYSNFTSDKVLNVCQSLYEGNGKGGYITYPRTDSIFLEESLASK
                     ASQTLDKLKVGLEYENKIKFSKTKRVFDSSKVDSHSAIIPTYIIPKSLSKDEQLVYDA
                     IKDRFVANFMPPAEYENTEIKTEVDNCTFLTKGKVLKSKGYLEVYNKEEKNDLLPLVN
                     KDDVVDVLEIKPLTKQTTPPKPYTEDTLLKAMKNCGKNVPEEDTTVLSGYSIGTSATR
                     ADVLKKISQVGYVKKKGKSYSITDLGKNLVEIFPVKDLFDVDYTGKLEKSLSDIQKGK
                     YTRKEYLTNIISFIYQNVNIIKQDASKNINTEAYTFDSKTKKFTKTKEKKQKKDVTNT
                     EKEVAISKDSNNKKEVKNGDENQSLGKCPICQGDVLEFDKGFACKNHKECKFVIWKND
                     KYLSLYKKKVNKTMVKNILKKGETKVKSLTAKNGNKFDATLKYDKNPDTGYFNWKIEF
                     DN"
     gene            complement(13515..14000)
                     /locus_tag="KR294_000500"
     CDS             complement(13515..14000)
                     /locus_tag="KR294_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBH0238617.1"
                     /translation="MDNNNILKIADSFLDFLFVLENNIFKESDLLKKFQNNSDIMKAY
                     FEECPMAPSHAKVILYLMTSNSSSISQIASNLGILKSNMTPIIDRLVEHGLVNKFPDP
                     KDRRILRVELTDKAFKLFDAVKAILKESLVKKLSNLSEEELTLLDEHTLKLSEIVKKL
                     G"
     gene            14252..15475
                     /locus_tag="KR294_000501"
     CDS             14252..15475
                     /locus_tag="KR294_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HBH0238618.1"
                     /translation="MKRYLIVFLMCSSLFLVGCGKTEESEPEKPIAVSVQKAIGGEIE
                     NTNSFSGTTKVKDETAVTAQTVGTVQEVYVKLGQNVRKGDELLSISSPELENSVKQSK
                     ASLDLAKASYSSATGGSLEAQVNQAKTALDNAKIQYEESQRNYDNNKILYEQEVISLD
                     QFKKIEFSLEQTKQQLDSAQRAYDTATSKSIPQAKALAKKQLDQAQVSYNLAMSNLDK
                     LTLTSPVDGTITAKNFDSKEMITQSQPAFIISNPNILEVDLNVAESDIGKFKKDGNVD
                     VIIEDQRILGKIDYVPSVVDPQTSLYPVKVLVNNTNNKFKAGMSAQVNLSVEKENGAV
                     TVPKKAIFEENGKKYVYIATKDNIAKKHLVQTGIVTEDKIEIKSGVSDKDTVIIGGIS
                     LISDGTKIFPVEKEK"
     gene            15479..18613
                     /locus_tag="KR294_000502"
     CDS             15479..18613
                     /locus_tag="KR294_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter permease subunit"
                     /protein_id="HBH0238619.1"
                     /translation="MNLTQTSVKRPLTIIMVFLVLIVFGGIGYKKMSINLMPDIEIPV
                     VMVMTTWTGAGPQDVDEQVSQKVDESLSAVSNVKSTISSSQESVSMVVAQFEFGTNLD
                     EIMNDVRSKVDALQTSLPDDAAKPTVLKLDMNAQAIGQLVISGGNENSSQALRKYAED
                     VIQPKIESIDGVTSADLKGGEKAQVNVIADPAVLSNYGVSLSTIKGVLSSSNKTFPYG
                     SITQGEDKIVLRAIDKLESLDDIKQIQIPVKGGNTVRLDNLCSVDYGYADKDSIYRYN
                     GKDSLVIDISKQQDANTVKVMQSAYKYVDELNKENPQFKIKIANDTSSYISESINSVM
                     SNLLISAVIAFIVIFAFLKSVRASLVVAVAIPISIIGAIAILYFTGESLNLITASSLV
                     ISVGMVVDNATVVIENIFKYRKSGRLSLDDCAIEGTRTVTNAILASTLTTIAIFLPIM
                     FTEGIAKITFGALGKTLIASLAFSFIGAITLVPSVFAKLSRGKNSQKMQEKDSPIFDK
                     VSEAYKKLLSVCLRHQRLVVISSLLIFVASLFGMGFIGMDFMPAADKGELSISIELPK
                     GLSLESNDYYVSMTEKKVSDIPEIKTLITTLTSDSNNSKASIAIELESQKNRKRTTDE
                     IEKEIIDRVATVPDCKINVSQNSSVMGGAGGADFTLEMKGPDLDVLKILGKEAEKEFS
                     SIKGFRNVETSLTDTTQEAQFTIDKHKAQEYGVNTAEIAGMLRTAINGDSVTTATIDD
                     YKVDVNLKFKADTIDSLEDIKQLKVNSATGKEVPLGAFSDIKMADGLQSISRTDGDFS
                     VNITATLDNLDAGTATKLALEKTNKMVIPKDYSIGVGGETEMMNESMASLGFSMVIAI
                     ALVYMVMVAQFESFSKPFIIMFCVPFAFVGVVLSLLVSGQSLSTVGMLGIILLIGIVV
                     NNGIVLIDYIEQLRKTNRNNDLIGLVSIGCAARLRPVLMTTATTILGMLPTALSLGEG
                     GETMQPLAIVIMGGLTVSTLITLVLIPTIYLIFDKWENKFSDKMPKIFGKITDKIGSI
                     KRKIIKKPKLKAKV"
     gene            18647..19945
                     /locus_tag="KR294_000503"
     CDS             18647..19945
                     /locus_tag="KR294_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TolC family protein"
                     /protein_id="HBH0238620.1"
                     /translation="MSKIVAISCGVGIITANLIPVYADNNTSSINKVDNSILSDSNKR
                     TSEKEILTAREAVSAALKNSEKLKMKSEEIKMLKEKLEVQDEFDSFTGSDNSFPYDQI
                     GLLKNQSEQAKGFMEDQIANDITNKFNDLVSRENELDKIKNNLEIKTKEIKDMKLKKD
                     LGLVTSLETESAELELQTLQNTQKAKLQELKNNQDYFKLLTNIDLNNYQLDKEYRFES
                     FRVGGSVDSYMEGKVNEYLKYDQLILERTEESFNDKDENKADLPDRPNLTRPVAPTKP
                     EQGNLTDDEYKVLMDKYEKDYDRYKKEVEAYNLERQTYAAGLTTYANYLQQKFNTENG
                     LVTLEDSKKALKKGLIDSYAQLLALEDTIQITKKQLDLSEKQLKNTKLRYDLGLITLT
                     DYKKQVVSNEDAKNSYDTLIVNYNSLKNGIEKPWILNTGK"
     gene            complement(20234..20479)
                     /locus_tag="KR294_000504"
     CDS             complement(20234..20479)
                     /locus_tag="KR294_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HBH0238621.1"
                     /translation="MTKCPKCGKEVSSRPGSICPRCGFKVADESLKIRCPEPSCRALV
                     SRKLDYCPKCGCKLRGYNISEFVNMVRCKIDETFDKK"
     gene            complement(20693..23320)
                     /locus_tag="KR294_000505"
     CDS             complement(20693..23320)
                     /locus_tag="KR294_000505"
                     /EC_number="2.7.9.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate, phosphate dikinase"
                     /protein_id="HBH0238622.1"
                     /translation="METKYVYSFGEGSKDMKSLLGGKGANLAEMTKIGLPVPPGFTIT
                     TEACNDYYVNNESIRAEIIKEIEEHLATLEKDLNKTLGCNKNPLLVSVRSGAVFSMPG
                     MMDTILNLGLNDNSVVGLAEATQNERFAYDSYRRFIQMFSDVAMEVPKYKFENVLDRV
                     KEAKGYTVDTELTTDDLKEIVKEFKAIYKKEIKNDFPQDPKEQLMLAIEAVFRSWNNP
                     RAIVYRKLNDIAHNLGTAVNIQSMVFGNMGETSGTGVAFTRNPATGENKLFGEFLMNA
                     QGEDVVAGIRTPQNISTLADVMPAVFDEFVKITHILEGHYKDMQDIEFTIENERLYIL
                     QTRNGKRTAAAAINVAVDLVEAGIIDEKEAIMRIEPNQLDQLLHPKFEDKALKEAKVI
                     AKGLPASPGAASGKVYFNADDVVKANEKGEKVVLVRLETSPEDIEGMVKAEGILTARG
                     GMTSHAAVVARGMGKCCVAGCGEIKVDEFNKEIRALDDVVIKEGEYISIDGSTGNVYL
                     GDVKKTEVSLTGNFEKLMNWVDKHKCMMVRTNADNPRDARAAIEFGAEGIGLCRTEHM
                     FFDEARLPAVREMILSNTVEQREKALEKILPMQREDFVELFKVMDGKPVNIRLLDPPL
                     HEFLPHDDETIEELSKSMGIKVSDIKKRIVDLDEFNPMLGHRGCRLAITYPEICVMQS
                     KAIIQGAIEAIKAGVKVSPEIMVPLVGEVNELKIIRKMIVETVDAIIKEEGIEVPYTV
                     GTMIEIPRACLTADEIAQEADFFSFGTNDLTQMAFGYSRDDAGKFLGQYVDEEILEKD
                     PFQVLDQNGVGKLVKMGAKLGREVKPELKLGICGEHGGEPSSVEFCYSVGLNYVSCSP
                     FRVPIARLAAAQASIKNPR"
     gene            complement(23381..24223)
                     /locus_tag="KR294_000506"
     CDS             complement(23381..24223)
                     /locus_tag="KR294_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase/pyrophosphorylase"
                     /protein_id="HBH0238623.1"
                     /translation="MLVKNLIIYAVSDSVGETAQQVAKACMSQFYVNETYEIKRFPYM
                     INKGVLLETLENAKAENALIVYTLVDEELCSIVERYCEREGLSCIDLMTDILREISKR
                     TGRKPKREAGIIRKLDESYFKRVEAIEFAVKYDDGKDPRGVLQADIILVGISRTSKTP
                     LSMYLANKNIKVANVPLVPEIPIPKEVFEIDTKKIIGLTNSPEKLNEIRTQRLKALGL
                     SSKANYANLERILQELDYSEEIMKRIGCPVINVSNKAIEETAGIILDIMKENGLKIYK
                     EIEI"
     gene            complement(24230..24868)
                     /locus_tag="KR294_000507"
     CDS             complement(24230..24868)
                     /locus_tag="KR294_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0238624.1"
                     /translation="MIIIQLNERQLKIIDIVKENEPITSESIASSLNVTRATLRSDLA
                     ILTMTGILDARPKVGYFYSGVSEINLIGKSVKEKTVEDIMSMPVLAKKDESIYDVIVT
                     MFLSDVGSIVIIDENEELCGVVSRKDLLKATIGGSDINKMPIGMIMTRTPNVVTLTKG
                     ASVLLASRKIIEHEVDSIPIVEYKGEDKNHMRVVGRISKTNITKLFLEIVDN"
     gene            complement(25304..26596)
                     /locus_tag="KR294_000508"
     CDS             complement(25304..26596)
                     /locus_tag="KR294_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HBH0238625.1"
                     /translation="MLDLNRKLAKLEEEGKKIKVALIGAGHMGNGMVSQMANMKGIEA
                     SIVVDINLELAHKAFTDAGIDEEIIDNVTNEKDAEIKLQEGKVLTCNDFLVACKTKSI
                     DVVIDATGGIAIGAEIALNSILNKKHIVMLNAETDCVVGPILKKLADDAGVIFTGSAG
                     DEPGAVMELFDFADAMGFEVRVIGKGKNNKLDLDCNPDTVREEAERKGASPHMIASFK
                     EGTKTMVEMALMCNATGFVPDVRGGHGIEATVNEVPKKYALKSEGGVLDNYGVVDFVN
                     GIAPGVFVVVAHKLKAVNDELKYLSMGDGPNYILYRPYHLCSLETPLSAAMAVLDHKA
                     TIVPKAGLVAEVMTIAKKDLKKGEFMDGYGAYTCYGTIEKYDVAKAMNAVPIGLISKK
                     TKVVKDIKKGEVITYDMVEIEKDTTLYHLRQLQEKIFG"
     gene            complement(26633..26989)
                     /locus_tag="KR294_000509"
     CDS             complement(26633..26989)
                     /locus_tag="KR294_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HBH0238626.1"
                     /translation="MKYEVKISGIGSLVKELMDESNCLIIYDETINDDDLKDISVIHS
                     IATLKSDVEIGDTLTIGNRDYCIVSVGDIAQKTLREIGHCTIKFDGKCEVNLPGEIHV
                     EIGNPDITIGDLITIS"
     gene            complement(27024..27383)
                     /locus_tag="KR294_000510"
     CDS             complement(27024..27383)
                     /locus_tag="KR294_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0238627.1"
                     /translation="MKLLVILFVAYILNTIFIMKQNKLYFKTLNRAKKKGDIVSTGKK
                     KSYFSKGSIAIISSDSDGFIKFGEILKGRTVMAKFKEIEEIEGLDIYSAEQKFKDEES
                     IVQAIKFIKEKINVSFN"
     gene            complement(27452..29425)
                     /locus_tag="KR294_000511"
     CDS             complement(27452..29425)
                     /locus_tag="KR294_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBH0238628.1"
                     /translation="MSVTEKIPSIDRKIFKILIMCSKKEFVSINSIANELNVTTRSVR
                     TYIKQLNKDLGNDIAVIKYIKGQGYKLEIKDEQILNKIIDMNRKNVFSLNSKEDRVEF
                     ILNYLIELDGFITLDSLADEMCVGRTTLVNDFQYVEKVLASYNLNLIKKQNTGMKLNG
                     NELDIRLFILNQLYKNSRKDFSNSKYFKGIKKEEIINLEEKLLTLFKKNNFYVTDEML
                     REVINYIVVLVYRVKEEKKVKDYDVKFDLLKSYDEYFIAREIKHIISGMFECTLNDEE
                     IIYLTIPLVSGNAPASECALNSSRISKNIDELMENIFNQIYVDMGIFINEDELRVGLG
                     YHLSFTLNRLLFNIKLKNVLLEEIKQNYILPFKLAQIAGKVIEKKYNLEVSEDEIGYI
                     AIHFSGYLERNSSRFYSIKKIAIICSTGLGTAKLLKIRVEKLIGNNPKIDTLSSFNLR
                     NINLDEYDIVFTTIDLDTSNINTIVLKINTIFDENKLREQLKTVLCLREGNIDTTNST
                     NLLINNLLDEDKFMILNEKTILASLEKMMDHLMDLGCIDDKFRKNIVNREEKSPTVFD
                     KGLLFPHSVNEKSDKFLMAVGILEEPIEYANRSIKIILMTMFPCENKIDSDLLVKIYE
                     EVLKIGQDVKLTNKISKCRTFLEFKKVLLKNLI"
     gene            complement(29647..30660)
                     /locus_tag="KR294_000512"
     CDS             complement(29647..30660)
                     /locus_tag="KR294_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HBH0238629.1"
                     /translation="MEENKILKIEKGTSGWGGPLYIKKEGNRNKILSMTAGGIHEVTL
                     KIKELLGCEIVDGFKTGVSDEEVAVVIIDCGGTARCGVYPKKKIPTINVNPVGKTGPL
                     AKFITEEYYVSDVNPNCISVVDGEDMPQKSQENKSENKSSIRKPDNYDEVKSKAQGEY
                     AKKNIILSIGQGAGQVVSKFYDAGRDTIQMVMNNVIPFMAFVSMLMGIILASGLGDWI
                     ARVISPLAGNIGGLLIISVICTLPFLSPILGPGAVIAQVVGTLVGTQIGLGAIPAYLA
                     LPALFAINGQAGCDFVPVGLSLGEAEPETVEYGVPALFYSRLITGPIAVIIAYGVAVF
                     ALR"
     gene            complement(30673..31218)
                     /locus_tag="KR294_000513"
     CDS             complement(30673..31218)
                     /locus_tag="KR294_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HBH0238630.1"
                     /translation="MENVITGLSKGAEWFIGLFQKGGEQFIGLVSGTLPTLIVLMVAI
                     NSLIKIIGEERVNNWASKLGKNSFTRYILLPLVSVFFLGNPMCYTFGRFLKEEHKAGF
                     YDAAVSFVHPITGLFPHANAGELFVWLGISAGLTTLGKETTTLALWYFIVGLIVIFIR
                     GIVTEKMYAFLTRKNRATNKA"
     gene            complement(31594..32463)
                     /locus_tag="KR294_000514"
     CDS             complement(31594..32463)
                     /locus_tag="KR294_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBH0238631.1"
                     /translation="MDYLKYFKKAVMYIENNLHENITVNDVAKETGYSYYHLTRLFKS
                     MFGESVGSYIKKRRLVSSTKELLYSDKKVIDIAIGSGFESSEAFSRAFKSIYKVSPIE
                     YRKNRIDVFVGKKKKLELDFMRHLVGNITIKPVIKEIEKIKVIGIKDKVILENNSLPD
                     LWEKFRKVHHIVPNTLPSKRVFGICEAISEIHLVSESMEFNEIIGLEVNSYDVIPNSF
                     VSKTIKEGKYAIFTHTGSLDNLDKTYEYIWGTWFLSSKEELDIRDDFEVYDERFLGPS
                     NVNSQIDIYIPIK"
     gene            complement(32615..33730)
                     /locus_tag="KR294_000515"
     CDS             complement(32615..33730)
                     /locus_tag="KR294_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
                     /protein_id="HBH0238632.1"
                     /translation="METLEVRNIELSGTNYEIGYRLGELVANMPEIIEGQINKSNLVS
                     KKEEKEMIELFDKYCPGLNEELQGFADAIQVNCNQILYYTMTYLKPGCSQVALAPELT
                     ENGHVLFARNFDFSHNMEDFVLCKTKVNGKYAHIGTTVMQFGRGEGMNECGLGVSQSS
                     CGIPVGNSDGLRKPAIVGLQFWAVIRYLLENCKDVDEALEYLKDMPIAYNINLLLADK
                     SGNIALVETLDGKKEVNIINSLESKREYFLHSTNHTHIDKLHKLEPQSMKNSIHRYKL
                     IKEYINKSKKIGEKELMNLLSSKYPNGLSCNYYNDFFGTLKSIVMDLNIGKFNILWGG
                     LENKWESYYLKNDIKSITQRININIEKAPSDFFDFIE"
     gene            complement(33966..35102)
                     /locus_tag="KR294_000516"
     CDS             complement(33966..35102)
                     /locus_tag="KR294_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBH0238633.1"
                     /translation="MKERIIQVADSKKEKILGLCQSLYDEPEIALQEYKSAKKISEFL
                     REEGFDVEENLAGMATAFKATKKNGDGPKIAFIAEYDALPGNGHACGHHLIASMGVGA
                     GIALSSILDTYKGEVSIIGTPAEETGDGKPYLIEHGVFDGYDAAMMIHPNSKTCVTPE
                     IIAIGGLDFIFTGKASHAGAKPYNGINALDAVVLLYNNINALRQQLVDGTRIHGIILE
                     AGTAANVIPDMGKVRLEIRAKEQNYFDEVVEKVKNCARGAAIATGCELEFYHFEPTCQ
                     GLNENKVLVDIFTKIMEEFGIYEDEQVMLGSTDMGNLSQIMPCIHPLMKFSENGEELH
                     TKEFLEASINSYAKDRVIDGIKILALTGFNLFENPELLKKMKEE"
     gene            complement(35158..36621)
                     /locus_tag="KR294_000517"
     CDS             complement(35158..36621)
                     /locus_tag="KR294_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine:cation symporter family protein"
                     /protein_id="HBH0238634.1"
                     /translation="MTDLVNTINGIVWSPVLVAMCLCIGLYFSLKLKFFQIRDVKEMF
                     TLLLEGDSSHVGISSFQGFATSMAGRIGTGNIAGVAVAIAMGGPGALVWMCIMATLGS
                     ATAFVESTLAQIYKDEHDGQYRGGPPYYFEKGLGWKKCSVLFSIVAIISYTFFMPGTQ
                     SNTLYLAMNQAFGFSKMTIAVASSIALAIIIFGGIKRIGLFAEKVVPIMGGAYLIMTL
                     VIIITNISLVPEAIVTMFKSAFGFGSVFGGMLGSAISWGVKRGIYSNEAGEGSGTYGA
                     AAAEVSHPAKQGLVQAFSVYVDTLLICMATGIMIVITGMYNVTGVCTALPGVEPGPQY
                     VQSAINTLHPQLGDIFIAIVLLLFTFTTLLAFSYMMETNVSYLVTRIKAEKHEKYIIN
                     VCRFMLIACAAMCCFIEPLTSWALGDICIGVLTYINLIAIFTLKKPAIKAYYDYIRQK
                     KMGIKRSDRTFNPIELDIRNAEFWENRYLKEDKHELN"
     gene            complement(37266..38525)
                     /locus_tag="KR294_000518"
     CDS             complement(37266..38525)
                     /locus_tag="KR294_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH0238635.1"
                     /translation="MGEKENGIKFGKLMFQLVIIAISWELVYIIPFIQYTLYDPILKA
                     LECTNTQLGFLLTIYGLGNIFGAPIGGWLADRFDYRKIILGSVFLNGVVSFLFAFNMN
                     YPFAVATWVGCAITSLVMNYPSMVKILRVIGKDNQGKVYGFNEAMVGVSGVVMGAIFL
                     YIYTCFATPTLGMRWVMISLGILSIAMCPVLWFVIKDVDIKEEREEAGEKMSAGDFIT
                     VLKSPNTWLVGISIFCVYSFTVTMSYFTPYITSVLGGSVALSGALAIIRQHGLKLFGA
                     PFGGYCADKLKSPTKVLLPIYVFGIAVIVLFLVLPASTPMTIFIALTFVVGILGYMGK
                     GIYYAVQDEVKVPVKYSATTIGIAAALGFSPDVFQFALIGHWIDTYGNKGYTYTFIFQ
                     IAILVIGILSCLYILKVKKRRASKLEA"
     gene            complement(38549..39757)
                     /locus_tag="KR294_000519"
     CDS             complement(38549..39757)
                     /locus_tag="KR294_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBH0238636.1"
                     /translation="MKYAKRMDMVKASAIRDSQKKIAQKVASGGTVISFAAGLPDPNL
                     FPIEEISEITQKVLNERGKFALAYGPTKGEDELLDLLVKRMKEEENIDTKAENIIITT
                     GSQQGIALSAMILLEKGDVVVTENPSYLGAINAFRPYECDFLGVDTDEEGMVTDDLDK
                     LLSENSNIKVIYVIPTFQNPTGKTWSLQRRKDFMEVVNKYDVIVIEDNPYGEIRFTPE
                     PLPTLKSLDTKDKVLYLGSFSKVLCPGFRVAWMCGNVDIIDKAELLKQGIDLQSNQFS
                     QVQVIEFLKKYNLNEHIEKIRAEYKKRCLLMLDAMKKHFPEEAKYTEPDGGMFIWVEL
                     PESINVDDLLDKAIDAGVAYVSGESFFANNGPKNTMRLNYTTMSEEQIVKGVEILAEV
                     IKKELNYACE"
     gene            complement(39787..40680)
                     /locus_tag="KR294_000520"
     CDS             complement(39787..40680)
                     /locus_tag="KR294_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional enoyl-CoA hydratase/phosphate
                     acetyltransferase"
                     /protein_id="HBH0238637.1"
                     /translation="MLKDFNNLLEEAKKLEPVIVSVAVAEDKEVLKAVKSATDLNIIK
                     PILVGDKDKIESISREIGLKGHEIIGCQNPDESVKKAVEIVKNKEAKVLMKGLVNTSV
                     YMRAILNKETGLRTGRLLSLLAVYELPQYHKLLYCTDSGINVSPNLNQKKDIMTNALL
                     TMKSIGMENPKTAILTANEMVDPKIQSTVDANLLVEMEKSGEIPKCIVEGPIAFDVAF
                     DAHAAEHKGIKSNIAGDVDLLVFPNIEAGNILGKSWLRFNKAKWAGIVLGATNPIILG
                     SRSDTAEIKINSIALACLASQ"
     gene            complement(40698..41756)
                     /gene="buk"
                     /locus_tag="KR294_000521"
     CDS             complement(40698..41756)
                     /gene="buk"
                     /locus_tag="KR294_000521"
                     /EC_number="2.7.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="butyrate kinase"
                     /protein_id="HBH0238638.1"
                     /translation="MKVLVINPGGTSTKISVFQDENEILKKNITHTREDLKNFSKVFD
                     EYDYRKQLIVDILSSENHSINSFDAVVGRGGLMKAIKGGTYTVSEEMIEDMRNEINGE
                     HASNLGALLAKTIADEIGVQSFVVDPVSVDEFDDVSRITGISDIEKASWLHALNHKAV
                     SRKIAQKLGGKYEDYNFIVAHLGSGISIVAHKQGKMIDGSGGRSDGPFSPERSGGLLA
                     YPLIELCYSGKYTHDEMVAKVSSIGGMYDYLGTKDMIEIENRIKEGDEKAKLIMDAFI
                     YQVAKEISMYGASLSGNVDRVILTGGISHSEMVVKGVAEKVSYLAPIEIVPGEMEMEA
                     LALGALRVLNGEEIAKTY"
     gene            complement(41913..42452)
                     /locus_tag="KR294_000522"
     CDS             complement(41913..42452)
                     /locus_tag="KR294_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase family
                     protein"
                     /protein_id="HBH0238639.1"
                     /translation="MLNEIICAGFGGQGVLTAGKIIMYVAYKAEKKITWFPSYGNEMR
                     GGSANCNVVVSDEKIANPCVKNPDILLGMNSVSVDKYESLMKKNGYMFVNESLVSKDR
                     KYREDINVIKVPVTEIAQNLGNEKAANICMLGAMVKSLDLFTKEEFESGMCEYFENQG
                     KGKFNSKNVEAFEAGYDYE"
     gene            complement(42465..43184)
                     /locus_tag="KR294_000523"
     CDS             complement(42465..43184)
                     /locus_tag="KR294_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate oxidoreductase"
                     /protein_id="HBH0238640.1"
                     /translation="MAKKAPAIMMCENMFCGGCGHSIVDRIIGEVLTEMDICQDTIIC
                     SDIGCNHMFQFSMNVDVVVPPHGKMGAAMAAMKRVRPDKYIFTIAGDGGAYAIGLGET
                     MSAATRNDNVIFLVMNNNMFAMTGGQMAPTTIEGQYTASTPAGRNYADHGSTFDVVKV
                     MGNLDIAYLARGTITNPKEINTTKRYIKKALEKQKEKKGFCLIEVLVPCPTNWGLKPV
                     DAMKRIENELVPKYPLGEFID"
     gene            complement(43187..44263)
                     /gene="vorB"
                     /locus_tag="KR294_000524"
     CDS             complement(43187..44263)
                     /gene="vorB"
                     /locus_tag="KR294_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate dehydrogenase subunit
                     VorB"
                     /protein_id="HBH0238641.1"
                     /translation="MQSLLIKGNEALAEGAIRGGCRFYAGYPITPQSEILEMMAWRQK
                     EVGGVFIQGESEIASVNMVMGASALGARAMTSSSGPGFSLKQEGIAYWVSAGLPAVVA
                     CVQRYGIGDGFIGAGQDNYWQAVKGGGNGDYHLIVLAPNSVQENMDMAYESFELAEKY
                     MHPVLILSDATIGQMVEPCIAPPMKEYDMDKAPWAAKGTPVGEKNKVITDITYFEDQD
                     TWQKGYIEKMRKVQEDEQRWEEIEIEDAEVVFVAYGISSRIAEGAVRDARAKGMKLGL
                     IRPKTLWPYPRKAFKKLSDSLKGLVTVEMNMMAQMKEDVIIACDNRFPVYSVATAQYM
                     AEVNQLIDFAQQIIDGKAKQEEVF"
     gene            complement(44292..44489)
                     /locus_tag="KR294_000525"
     CDS             complement(44292..44489)
                     /locus_tag="KR294_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBH0238642.1"
                     /translation="MEKVKLSVERCKGCYLCIEACKKDAISLSDYTNKKGFVTIKVDE
                     EKCIQCGACYTMCPDLVFEIL"
     gene            complement(44772..45539)
                     /locus_tag="KR294_000526"
     CDS             complement(44772..45539)
                     /locus_tag="KR294_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HBH0238643.1"
                     /translation="MGEIINALDRALDIILLLYHEKREMGITEISKAMGVYKSTVHRT
                     LVTLENKGFVIQNAENGKYWLGINLYAIGMVVGEKMSLTEIVKPYTKKLNQEFNEVVN
                     VSILEERAQDSPRSIIIHKEYGSNQLLSVNPSVGSSSECYCSAVGKCLMAFNDSIDFE
                     KYRKTPIHKYTEHTIDNWDDMMLFLAKIKEQGYAIDDEELEHGLTCIGAPILDKNNKA
                     IAAISLSGPTIRMREGDFEYKIKRVIETAKSISELFR"
     gene            45819..47366
                     /locus_tag="KR294_000527"
     CDS             45819..47366
                     /locus_tag="KR294_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrite/sulfite reductase"
                     /protein_id="HBH0238644.1"
                     /translation="MDNFKKILLNELPNFKEYSSKFLNGEINKMQYKGFSGGYGVYAQ
                     RDKKSFMIRLRVSAGVLSQYQLNKIYEIAIKHNLDKIHLTTRQAIQLHDLSINSIVDI
                     MEEGIKNDIFTRGGGGNYPRNVGLSPLSGVDPSEVFDVTPYAVATDKYFIKNATTYHL
                     PRKLKVSYSNCYTDTAHCSIQDLGFVATLKNDEPYFRVFLGGGLGKQPKVALELDELI
                     KPKDALYCVEGMIKFFMDYGNYENKNRARVRYMVESLGEELFLEKFKEYYKLEKENGS
                     LELNIEEIDYSKPGVKIDIQDSRLIPQKQDGLYTVYIHPVGGILLTKDLSTLLKELDN
                     VENPMIRLGMTEGLYILNLNGNEAKRILEISKTISCNSQLEQSISCIGVPICQMGIQN
                     SQKMLHEIIDYFRLQNNEEILNKAPKLYISGCLNSCGVHQVGSIGLCGKKKNVDGIST
                     DAFELFVGGSFEIGKTRLGKSLGDFKASDIPEMLYKISDASSGNFYEWVNSNDNILNK
                     ITDKYKI"
     gene            complement(47532..49598)
                     /locus_tag="KR294_000528"
     CDS             complement(47532..49598)
                     /locus_tag="KR294_000528"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HBH0238645.1"
                     /translation="MKNYLLFEIGVEEMPSRFVGSTLEQLKNNLSKLFDENRIAFDKI
                     NAYGTPRRLTLVVEGLSDRQSDLEEEIKGPAKKIAVDAENNLTKPALGFIKSKGLSES
                     DIYFKQVGKEEYIFATIKQDGKETSEVLKDILPETIKSVVFPKAMRWGGKNLKFARPI
                     RWIVALLNDKVLEFDLEGIISSNVTKGHRFLGESTIEVDSIEDYFEKLEKNYIVLDQN
                     KRKEMIRKQCIEVANSLGGEVEFDEDLLEEVTYLVEYPTAFYGEFDVDYIKLPKEVVI
                     TPMKQHQRYFPVLKEGKLLPNFIAVRNGDSYRIDNVKAGNEKVLEARLADALFFYRED
                     TKRNLESYIEKLKTVVFQVKLGTIYDKTLRLEKLSADILDSLGLVDEKADTIRAAKLS
                     KADLVTGMVGEFDELQGFMGKEYAKVGGENDVVSEAIFEHYLPRFAGDILPKTNAGVA
                     LSIADKLDSIAGFFAIGIQPTGSQDPYALRRQALGILSILMDRKVAVDIKILIEHALD
                     NYSELDFNKEEVVEQIMNFFNERVKNLFKDLGIRYDVVDAVLSSDINDVSDMHMRALE
                     LNNWLEKDELVEMLTAFNRVSTLAQKAESDKIDESLLKEDAEIKLYNEFKQVKVKVNE
                     LLKDKKYGIALDEFASLRPVVDNLFDTVMVMDNDEAIKNNRLALLKQVYDTMLGICDL
                     SKIVYK"
     gene            complement(49598..50476)
                     /gene="glyQ"
                     /locus_tag="KR294_000529"
     CDS             complement(49598..50476)
                     /gene="glyQ"
                     /locus_tag="KR294_000529"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HBH0238646.1"
                     /translation="MNFQEMILALQKYWSKQGCIMMQPYDIEKGAGTMNPNTFLRSLG
                     PEPWQVCYVEPSRRPADGRYGENPNRLYQHHQFQVILKPSPDNIQELYLESLKEIGID
                     PSEHDIRFVEDNWEAATVGAWGLGWEVWLDGMEITQFTYFQQVGNIECELETGEITYG
                     LERLAMYIQEVDSVYDLKWNDKITYGEVFNKAEYENSMYAFELCDADMLFNLFDIYEK
                     EALRLMENGLVIPSYDYVLKCSHAFNTLDARGAIGVSQRASFIGRVRNMAKTVAETFV
                     KQREEMGFPLLKDGDK"
     gene            complement(50636..51235)
                     /locus_tag="KR294_000530"
     CDS             complement(50636..51235)
                     /locus_tag="KR294_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4342 domain-containing protein"
                     /protein_id="HBH0238647.1"
                     /translation="MSSNITIEMVDSVFERVPGATYAEAKEALVMCNGDVIEAVIYLE
                     NKKNTCNCKAKSAKETMEEVFGKDGENIKFQLKELLRKSSVVRIIVEKDGKTMMNIPL
                     TVGVVGLAFVPLATLVGLSAAVISKYRIKVQNEEDGEIVDLGELNEEKLHVLKNMITN
                     AAKDVKDVVVDKKEDDKDVTADLMKEESEKNKEDEDENK"
     gene            complement(51228..52001)
                     /gene="recO"
                     /locus_tag="KR294_000531"
     CDS             complement(51228..52001)
                     /gene="recO"
                     /locus_tag="KR294_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HBH0238648.1"
                     /translation="MIILNTQGIVLKAIRYKESDIILTLFTRKLGKVSAIAKGAKKNK
                     SSLLSSSQLFSYSNFTLKKQGNMYKVTQSEIIKSFYNISYDIEAFSYATYITKLVENS
                     ILENQTNNRLFILLAQTLYLYTQDNTDNRFITAAFELKFLDYIGFKPIVNKCINCECK
                     ILQNSVFNIYEGGILCSKCSKLFDNNIKLDLTTISLMEYVLRNDILTCSKAKVSKYIT
                     HELENILDKYLKVYVDNINFKSLHVLQSVKNNKGVDNDE"
     gene            complement(51967..52122)
                     /locus_tag="KR294_000532"
     CDS             complement(51967..52122)
                     /locus_tag="KR294_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqzL family protein"
                     /protein_id="HBH0238649.1"
                     /translation="MNNISWEVFKKTGSIDAYLYFCDCKNIHEEIEEVREKKEDDDNP
                     EHPGDST"
     gene            complement(52195..53574)
                     /gene="mgtE"
                     /locus_tag="KR294_000533"
     CDS             complement(52195..53574)
                     /gene="mgtE"
                     /locus_tag="KR294_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HBH0238650.1"
                     /translation="MDRKLDASQDLLYEVKSLIDNNKVLELRELIEEYHIIDIFDIME
                     NLEEDMKIQLFEVLPLDMASSILEEGSVEFFISILSKLDVEHSKNILELMSLGDMADK
                     LSELEEEEREHIINLLNQENADYVKELLFYDEDSAGGTMTTGYISINKDMTALEAIDH
                     MREEAEEAETIYYIYVVDDEEKLVGVLSLRELIIARDANIVEDLMSENIISVYVDEDR
                     EEAVRLVSKYNLIAIPVVDRQEKLKGIITVDDIIDVMEEEATEDMYKFAGSSEHEREV
                     AEKENPTLREQIISALRGRLPWLIITLVGGLLASLILSNLDYIMNPVYAPLVFFIPVV
                     IGMGGNIGTQSSSVTVITLSNKDLNFSNVVREGIVGIITGLLCSIITGIVIYFVMRKL
                     DIVLIVSISLFINMVLGATIGAFMPVLLKKMDADPSTVSSPIISTALDITGIAVYFII
                     TTALLSKIV"
     gene            complement(53586..54479)
                     /gene="era"
                     /locus_tag="KR294_000534"
     CDS             complement(53586..54479)
                     /gene="era"
                     /locus_tag="KR294_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HBH0238651.1"
                     /translation="MFKSGFVSIVGRPNVGKSTLMNNVVGEKIAIMSDKPQTTRNTIQ
                     AVYTDEEMQIVFLDTPGIHKPKNKLGEFMVKAATEAFKNVDLILFVVDDSKKIGPGDR
                     KIIEDLRSVKTPIILVVNKIDQLDQKDELFDIIKMYDREGIFKEIVPISALKGKNTDT
                     LIKVIQNYLEEGPKYFPDYMITDQPERVLIAELIREKVLHYLNDEIPHGVAVEIEKMK
                     ARNDKEIVDVSAVIYCERDSHKGIIIGKNGRKLKGIGKSARQDIELLLGSQINLQLWV
                     KVKENWRNLQNYINNFGYNDK"
     gene            complement(54543..54944)
                     /locus_tag="KR294_000535"
     CDS             complement(54543..54944)
                     /locus_tag="KR294_000535"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HBH0238652.1"
                     /translation="MDNIELLRLAEDARQHSYAPYSGFRVGAALLTKSGKVYTGCNIE
                     CASLGGTNCAERTAIFKAISEGDKDIYKIAIASDNSENNEQTYPCGICRQVIIEFGSD
                     IKIITGYTKGEVFEHSIKDLLPNYFSGNDLK"
     gene            complement(55063..55782)
                     /locus_tag="KR294_000536"
     CDS             complement(55063..55782)
                     /locus_tag="KR294_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HBH0238653.1"
                     /translation="MKPEKTRQGIIKAFNAAIEGILYTFKFERNMKIHYLGSVAVLII
                     SLFFNFSKLEMIMLLMSICLVVVAEMFNTAIEKAVDLVTDEYHVLAKIAKDVAAGGVL
                     VAALNSVVVGYILFYDKLTDISGILIYKIRESELHITLICILLVLIAVVVVKALTSTG
                     TPLKGGMPSGHAALAFAIATAITLMTERVVASTLAYIMAVLVAQSRIEGKIHTFWETI
                     AGALLGVLIAILVFQLGMFYN"
     gene            complement(55788..56249)
                     /gene="ybeY"
                     /locus_tag="KR294_000537"
     CDS             complement(55788..56249)
                     /gene="ybeY"
                     /locus_tag="KR294_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HBH0238654.1"
                     /translation="MDLILDDRQDKLEVSEELIEKIKDIIIECLDYEGYDDNYEVSLS
                     FVDNKEIHELNREYRGVDRVTDVLSFPLLSDDFEDVELEEESLGDIVVSLERALEQSI
                     EYNHSFEREVCFLICHSMFHLLGYDHDTDENTKEMREKEEHILNKLNITRE"
     gene            complement(56306..57421)
                     /locus_tag="KR294_000538"
     CDS             complement(56306..57421)
                     /locus_tag="KR294_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HBH0238655.1"
                     /translation="MKIIVIKIVIIVKIIIAITTNKIKLKILGGLIQLIIQKKFTIAD
                     GNFERELFGNFDENVKLIEKTLNIDVILREGNIILIGEEKNVDSALKLMNELHQTVSN
                     GKHLDKQSISYSLSLLLEGSEQKIKELEGTIVITQRGKAVQPKTLGQKEYIKLIENND
                     ITFGVGPAGTGKTYLAVAMAVKAFKRDEVSRIILTRPAVEAGESLGFLPGDLKDKVDP
                     YLRPLYDALFEMLGADKFNKYLERGTIEVAPLAFMRGRTLDNSFIILDEAQNTTSEQM
                     KMFLTRLGFGSKAVVTGDVTQTDLPQNKKSGLIQATEILKGVPGIGSIMLTDRDVVRH
                     ELVQRIIRAYEKHDKREEFKKEERKKAKMQEKTFKRK"
     gene            complement(57360..58703)
                     /gene="yqfD"
                     /locus_tag="KR294_000539"
     CDS             complement(57360..58703)
                     /gene="yqfD"
                     /locus_tag="KR294_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein YqfD"
                     /protein_id="HBH0238656.1"
                     /translation="MISFIRGYYVIVVEGVGLEQFLNHLIRNGISVYNVTRIKNTKME
                     FHIDRQDIKEFKNVYRGSKFDIKVKQKTGVPFIIKRVYKHKGMWICALVSLFLLMSTS
                     QFVTDVYIQSPEGIKKEALRNELYKVGVRPGVYKKSIDRKEVRDHMMSKFNDVAYLSI
                     NVKGTNIFVTVTKKAESLKSTDQSNYCNVIALKNGIIEKVIPRSGKSVIKSGDIVQKG
                     DVLLNGANTKSIPEVWASTFYESTKKASYVDTVNKKTGEKKNIYTLSFYDKEFTMRKN
                     IKYKDYVVENKEKKLSIGNYTFPIKIKTSTFYETKKVEVKRNKEELKKELSEKALKEL
                     EYIIPASARIIDVKHNFKVNKNMLEYLITVQTSENIAKIYPLSKSEAERFIKEESKPD
                     EGEEEVPSNPEKRPLNDIRNEFDEDNKDNKDQNNSDENNSNQNSNNSQNNNSNNN"
     gene            complement(58716..58952)
                     /locus_tag="KR294_000540"
     CDS             complement(58716..58952)
                     /locus_tag="KR294_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YabP/YqfC family sporulation protein"
                     /protein_id="HBH0238657.1"
                     /translation="MLEISTDLQVNQPVITVTSNTFISIENYLSILEYEVDLIRIKTK
                     VKTIKISGDKLSLKYITDSEIGIKGIIYNVEYVD"
     gene            complement(59165..59728)
                     /gene="raiA"
                     /locus_tag="KR294_000541"
     CDS             complement(59165..59728)
                     /gene="raiA"
                     /locus_tag="KR294_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HBH0238658.1"
                     /translation="MQIIVSGRQMKLTDGIKGYVDGKLSRLEKYLDPESEVKVTVSAK
                     KDRQKVEVTIIPINGQIIRAEDVEDDLYAAIDIVCDKLSRQVVKYKTKVKDKVQNNKS
                     IRFENLDFIDNSSEFDDYDYDDEEDENIVIERRKKFNVKPMSSEEAILQMELVGHNFY
                     MFRNQDNFEINIVYKRKAGGYGLIEQD"
     gene            complement(59921..60418)
                     /locus_tag="KR294_000542"
     CDS             complement(59921..60418)
                     /locus_tag="KR294_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="HBH0238659.1"
                     /translation="MIISVKEIRNFLINIFIPLIIGYLSSILTMIISGTDISTYYLQL
                     TKPSFAPPAFIFPIVWTILYILMGISSYLILRKGYNLPKVRDAIFYYGLQLVLNFIWS
                     ILFFGFGLRFTALIDIIIMILVSIIMISKFSKIDKRSGYINLIYLMWLVYAGFLNYFI
                     WFINK"
     gene            complement(60529..60972)
                     /locus_tag="KR294_000543"
     CDS             complement(60529..60972)
                     /locus_tag="KR294_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HBH0238660.1"
                     /translation="MSLKQKLQEDLKSSMKNKDTVRKSVVTLIRASIKQYEVDNRVEL
                     DEDGIIDVIAKQLKQRRDALVEFEKAGREDLIKETEGEIEVLKEYLPQQLSEEELEEI
                     VKSTISEVGATSMKDMGKIMSVIQPKVKGRADGKLINKLVKQNLQ"
     gene            complement(61002..61181)
                     /locus_tag="KR294_000544"
     CDS             complement(61002..61181)
                     /locus_tag="KR294_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HBH0238661.1"
                     /translation="MSEVRVRENETLDSALRRFKRQCAMSGIMSEVRKREHYDKPSVK
                     RKKKAEAARRKNAKK"
     gene            complement(61344..61694)
                     /locus_tag="KR294_000545"
     CDS             complement(61344..61694)
                     /locus_tag="KR294_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine triad nucleotide-binding protein"
                     /protein_id="HBH0238662.1"
                     /translation="MDCIFCKIANGEIPSTKVYEDDRVLAFNDLNPVAPYHILVVPKK
                     HYDSLIDIPDKEMDIVSHIHVVINKIAKEKGFDQTGFRVINNCGSDGGQEVKHLHYHI
                     LAGKKLPNYEAGQN"
     gene            complement(61737..63035)
                     /gene="mtaB"
                     /locus_tag="KR294_000546"
     CDS             complement(61737..63035)
                     /gene="mtaB"
                     /locus_tag="KR294_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-
                     methylthiotransferase MtaB"
                     /protein_id="HBH0238663.1"
                     /translation="MKKVAFYTLGCKVNQYETEAMLELFEKDGYEQVNSEEYADVYVI
                     NTCTVTHMSDRKSRQYIRRVKKKNPDAIIAVVGCYSQVSPEEILDIEEVNLVMGTNDR
                     RKIVEEIKKINSSKKVSTVDDIMKVKAFEEIEISQTNGKTRAFMKIQDGCDRFCTYCI
                     IPYARGRVRSRDIDSIVDEVKKLANNGYKEVVLTGIHVASYGKDLKDRDIKLLDVIKQ
                     INQIEKIERIRLSSVEPILFTDEFVNEVLKMDKVCPHYHLSLQSGCDETLKRMNRRYT
                     TLEYKTIVDRLRSKMPDVAITTDVIVGFPGETNEEFKKTYEFLKEIELSQMHIFKYSP
                     RKGTPAATMENQVDPQMKHFRSEQLLNLSKVNFNKFATKFIGRELDVLFEQNIEGNKY
                     EGLTSNYIRVVVESDKNIQGQILKVKINDVKDEYVEGILL"
     gene            complement(63037..63795)
                     /locus_tag="KR294_000547"
     CDS             complement(63037..63795)
                     /locus_tag="KR294_000547"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HBH0238664.1"
                     /translation="MDRFFVEKNNINLQDKTCTIEGEDVKHISKVLRCKLGEKLEICD
                     KNNNEYICEIMNIDKSIVNLEILEKVDINRESELKVRLYQGLPKAPKMEMILQKLTEV
                     GVEEIILVQTKRSVVKVDDKKEDKKFERWERIIYEAAKQSKRGKIPKLRGVLSFKEAL
                     EDMKKNNVNICPYENERTVSIKHALKKCDSNIDSVGIFIGPEGGFSEEEIEQIQKNNC
                     NVVSLGPRILRTETASVVASTIALYELSDLGGEK"
     gene            complement(63814..64761)
                     /gene="prmA"
                     /locus_tag="KR294_000548"
     CDS             complement(63814..64761)
                     /gene="prmA"
                     /locus_tag="KR294_000548"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HBH0238665.1"
                     /translation="MNNWIEVTIKTTTEAVEPITNILYEQGAGGAVIEDPKDFLFQKK
                     NELDWDYVEEEVFKKNEEDDVLIKTYVSEEKNVMEFVEIIKQKVLGLKDFGIDIGEGS
                     VSLDQVNEADWANAWKAYYKPTKVGQRVVVKPTWEDYAMQEGDLIIELDPGMAFGTGT
                     HETTSMCIRELEKYVNKDSKVFDIGCGSGILAIAAAKLGAKEVVAVDLDEVAVKVAKE
                     NVLENKVEKSVSVMHGNLTDVIKDKADVIVANIIADIIKILAKDVQNFMKEDAIFISS
                     GIILDKVEEVKESLIENGFEIVEVQKLGEWSAIVSKLKK"
     gene            complement(65203..67611)
                     /locus_tag="KR294_000549"
     CDS             complement(65203..67611)
                     /locus_tag="KR294_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated helicase/endonuclease Cas3"
                     /protein_id="HBH0238666.1"
                     /translation="MKNIMQKEILAKSYNLRTNQQEQTLVEHIKDLFEVLESILELNL
                     YSDKDVEILKICCALHDLGKINSIMQQKMEINNKISYSCSEEERKKLESDKKSLKKIA
                     RHNIFSGAFLKDILEKMNLSEEDKLYIYKSIMLHHGNYEDYMRLSISKVQEEIYEYIE
                     KGILEKEEFNLKDIESYINSILNVDFKFGEDVLDYDYIDKLSESMFIDSDYNNGQIDD
                     SVLNYRKFKYILYKGMLNLIDHSASSRQKGIKFYNDFTDEEIDNMILNEIYKSQGNLE
                     KNNIEFNTIQKRLRELSGRNVLTVAFTGSGKTAADYRKTFKRKFFLVPNKISAESFYR
                     KNIFQNKNDLDTRSSNDYIGLLHGDINLYSENEDNGEHDFVLTLRDIDLSINFCKPCV
                     IATVDQLLLSMFKFPGYEKIFAAVKNASITVDEVHLLEPKMFLILIYFMQFACKYLDV
                     DFHLMTATLPKSYKEQMINKGIIFQEESNENVTDKGEIVFIESNKEEEICEGKDVKVS
                     FIKEKEIKSIVEDALENKQKILIIKNTIDSVNRTYEFLKENLSDKYGGVDIDVLHSRF
                     KFKDKKEKYSKILNGEGDIWISTQSVEISLDLDFNIIISDLATMDSLIQRMGRCNRNN
                     KYEYGNFYILPSEDKIYDNKLKNTTKNILKDILKTNSIFTMGIRKTILDDYYDNSVVK
                     KYFEENFISCDKEIKNIYGINKEIFDGLDLIFNFEPYKNIVDSKKEAAKIFRDVDVSY
                     KIILEEDFYKEDRELQQDSIQVSGFIFNRLYYYGLISKVEGYMVLKSSSKFEYNSTVG
                     LILK"
     gene            complement(67638..68435)
                     /gene="cas5"
                     /locus_tag="KR294_000550"
     CDS             complement(67638..68435)
                     /gene="cas5"
                     /locus_tag="KR294_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated protein Cas5"
                     /protein_id="HBH0238667.1"
                     /translation="MKVLQCKLKQPTAHYRDPKVFQNEYISTLNLPSKTTIMGMITYL
                     CDRRLNSDIDIGIIGTHHHRELEFSRGENIDFWNEYTNMRKGKDKEKFLLQGNYYDYY
                     KEHKAQNSILNYEVLKEVELTIFISCKDDEELEFIRKKLESPCKYANLGRKEDFVIPS
                     EKGCFVKEVELKEVIPMNTRDAIKENIKLKNTYVRVDLRDKENVETIINQGVLIALPY
                     KYKDLEANRDDRVYEFCHYIYVDNDGIYPKNIKVNVCIDTKEVFTWL"
     gene            complement(68451..69467)
                     /gene="cas7i"
                     /locus_tag="KR294_000551"
     CDS             complement(68451..69467)
                     /gene="cas7i"
                     /locus_tag="KR294_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated protein
                     Cas7/Cst2/DevR"
                     /protein_id="HBH0238668.1"
                     /translation="MNEKRVKGVTLTILTESPVPLSYDQGYGNYTPIKKEQYRDKVHA
                     KTSIATITYDLRRILHQEYGWNLSNIVFGKKGNIYPSIKKNVGCVDENGLETDVFGYL
                     IPLKEKGSISKASPLRIIPFRSLNSYRGSTQLITNRGFLSSEFGRKYYDEREENEVLR
                     DENFPTTQALAIEETLSDYYVYTITLELDRIGVVEVEEDGKLLLPEERKFMSKELREK
                     AVKDILDAITVFTRNIKHSSVLLKPLAVMGGAFDKVVPFFWDDVDYNADSGEINLEGV
                     IETIESYSLKESNTILAINDRLKISNKKELNKFNLSKYPVKEIKNLADRLEIGEDNMW
                     YLKE"
     gene            complement(69487..70962)
                     /locus_tag="KR294_000552"
     CDS             complement(69487..70962)
                     /locus_tag="KR294_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0238669.1"
                     /translation="MREIKAKFYRSGDIVRDIGIVYFCELLMDLKNELEKNDYKLKFT
                     CELNRNYLSLESAEYIDPKYISDYILENQLFKVFKNGKKETLEKIFSNIDNLTYVNFI
                     EELDKSSATEKQKEGIKKDFKNRRFPYVRNSGKYGLNTSLENMEKNVKRIVDIVIKSN
                     IEIDEIDKLDLKQYEEKDSVCNVCNINKTTKLDIDLRERKDSKYNFLFRGAEKSGFKR
                     SGQVESNICFECEFFNLMCLLYINLKRPMVFAYTNDLRELAFLNHKIMLKRKMYSDKS
                     FYKKLLHEKISSIRLYRIDIDTNKGIILKFDSIIEYKELLKKIELIDIIDNYNFSREP
                     MNTRNLGKKMINNGNLSNLKELLLDNISVLRQLTGTSREMDFVSSSYNIGLYIKLCWI
                     VDGREEYKMKNYIESNLIYSRVGKDLFNKMTDESRRKNFSMKVIQLLKSNDRTQLFQT
                     IMHVLVSNGILIGEGFVEGLMQSSELELNTNVGLFIQEIMK"
     gene            complement(70967..71704)
                     /gene="cas6"
                     /locus_tag="KR294_000553"
     CDS             complement(70967..71704)
                     /gene="cas6"
                     /locus_tag="KR294_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endoribonuclease Cas6"
                     /protein_id="HBH0238670.1"
                     /translation="MSRISIFMESCNGKFPNENSMLSVSFIKNILNAENKDFAKNIFN
                     YGEERKNNKQIKDINTAIYIPNLIRSKNELLVDGDIIFNISFYNYSMFSKLYNGILKV
                     KELEYKGYRFKIKNIKIHKEHEIKENGVIFKTMSPIIVKNKEGKYLDVEDSNYIECLN
                     YIANLTLESIRGSGLRKPLEFIPLNFKKRVLKEKIRGFKEREFYYINAYAGTFFLKGN
                     MEDLNALYKMGIGYRRTENAGMVDILK"
     gene            complement(71805..71981)
                     /locus_tag="KR294_000554"
     CDS             complement(71805..71981)
                     /locus_tag="KR294_000554"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0238671.1"
                     /translation="MNLKKKEKIVKPVLKKLTEIVLNILSKKILNYAIYAISVLIVTK
                     VVINIDLYISILYY"
BASE COUNT        23394 a        12700 c         7852 g        28062 t
ORIGIN      
        1 tattttaaat tactagttag tcactctttt cgggttattt atctcctata tattaaagtg
       61 tcacacctaa atagttaaat cattatcctc ttttatcttt attgccttta caaatccatc
      121 tgcaattaca aaactcatca gagaagttat aaaatataca aatactggaa cagtaaaata
      181 aaatccaaat cctaaatcta gaaatctcat tccttttcca gtagtaccaa aagttgaaat
      241 aaactcaatt agagagttta aaagcaaaag atatccaata atcctaaatc tttttacatt
      301 ctcttttaca aataggctat attcagaact acctaatact tctatcaatg attttataat
      361 gataaaatat gatacaccta aaataaacat taatattcca taaatagtac cttgtagagt
      421 tgcttctcca ctaaaacaga ggtacataaa acttttaaat cctcctacaa caattactaa
      481 tcctaaaaga aaaaataaaa tttgtaatat accacttagt aaatttttta taagtttatt
      541 agacatcatg ccaactcctt taaaatattt tatatatagt ataatacatt atattatatc
      601 gtttttaaat aaaaatatta taattaacaa tatattttta ttgttaatta tgcaaataaa
      661 aaagagtata ataaaagcct ttaaaataca tttttttctt attttaaagg ctttttatat
      721 tctacatttt tattttctat attatatcct ttgataatcg ttatatctaa aatagacctt
      781 cttaccctaa atataagtat ctttataact agaatagtcc attacaacag cacctccata
      841 ttaatccact gatacctctt tattatcaat atctaaaatt gaaattttac aattcccacc
      901 caatttttct tgaactattt tagctaattc atttaaagca ttttcaaatt ctttaaatct
      961 actttcatct actaattcaa tgcataaaaa ggcattgtta gtatcttcag taagcattgt
     1021 tctcactgct tcacgccaat tccaacatct acaaattgct ccaccatcat ctttataaat
     1081 tatttctcct tcatatggaa atgaattttc atctgtccct agtgggataa actcctcatt
     1141 accaattgct ctagttagcc taatatctcc tataaattta tctatatcct cccctccaca
     1201 aggtaatgca tattttaatg agataaaatt gtagatatcc actaaagggt taatagttcc
     1261 tatattattt ccattatgaa ctctttttaa taatgcttca atagaagacc ttgctccttt
     1321 tttcgtttta aattttttaa atgcttctct ccatacttta atcacttggt tgttgctaaa
     1381 ttctgagtcc tccaagtatt ttaatgcttc ttcttctccc ttcaaaatta ttttcttata
     1441 gtcttcatct tttatagagt tatctatatc attacaaata acaactccaa tttttgcact
     1501 aggaaataga ttccaaaatg catcctcaat aacaaatttt ttcattagaa aacctcctca
     1561 aatttaaaat atgtaaaaat aaaaaagcct atagaaatat tcttaaatat ctcccaggct
     1621 tttatccttc cgtgtacaca acaattgcgc gttttctctt ggacctgacc attataaaat
     1681 gcggaaccct agaaaactaa attataagtt ttttaattta caaaatacaa ttaaatttta
     1741 gcataatata gcatttaaga caatattcta ttatctagtt tgtacattaa aacaatttgc
     1801 cattagatta taattatggt ggcaaatggg tggcaaatca ccttttttat tacatttttg
     1861 tttgtttaaa ctattgaaaa tactatattc ttacaatttt aatcaatttc tgatttaaat
     1921 ggagtgtcat cagcttttgc tattctatac tccttatcag ttatataacc aagctgatgc
     1981 atcttataca gtacaatcac ttgtctcttc ttagcctctc catggtcaat ataccttgca
     2041 ggattatttg tcataccagc taacatagca cactcagcta aatttaattc actaactttt
     2101 ttaccaaagt agacttcagc tccctttgca gctccatatg catttttacc tagatacata
     2161 ttatttaaat atgcttcaag aatttcatcc ttagtcataa tcttattcat ctgcttagca
     2221 ttatacatat cccttatttt ccgcttcata gttttatcat tactagtaag caggtttttt
     2281 gaaacttgca tatctatagt acttgcacct tgtgttgtat ctgtaaacac attgtttaat
     2341 actgacctaa ctagagaaat aacatctact cctttatgct tataaaatct ctcatcttct
     2401 atggaaacta ttgcatgttt taaatcattt ggcatttgtt ttatacttac aacctcacta
     2461 cttatatatt tagacctaat taacttttta gtaacttctg gtgacccttt tatagctgaa
     2521 actgtaaata ttgcacctgc cactgaaaat ataattagtg caactaacat aatagataat
     2581 aatgccctaa ctattctaat ccttttttgt ttttttcttt ttttactttt taattttttc
     2641 tctctttgtt tatactcgac tcttcttctt tctctttgat tgtaatctgt atttaaaggt
     2701 cttacattat ctcttgtaaa actatctcta tctcttttta taagattctg tgaatctact
     2761 ttttcactca ttcttttact ggaacttgta ttaggacttt tatttttttt atttgccgaa
     2821 gtataagaat gtttagattt tttattacta tctttgttgt tactaatttt tttacgtctt
     2881 attttattat tatcattatc attgtaataa cccattttag tctcccttct tcatataagg
     2941 tacattatac attgttctac aaaataaatc aaagaacaaa attgtaagct taagggtcaa
     3001 ttttataaag gatattttca ctaattttct ctatatttat aattaatatt catcttttat
     3061 tttcaaaaat agttttgcag ttgctaatgt atcactgtca gctctatgag catttatatt
     3121 ctctatgttg taataagcac aagctgtttc aagtttcttg ttttttcctt tataactttt
     3181 acattttttt aataactcta ctgtacatat ataattgttt attggttcta aatctaacat
     3241 tctaagatag taatttaaaa attttaaatc aaatttcgca ttgtgtgcaa ttatagttct
     3301 atcacctatg tattttctaa atctaggtaa aactaattct agtggttctt cattttctac
     3361 catttcatta cttatatgtg tcaattctgt tataaatgaa gaaattatcc ccttaggttt
     3421 tatcaacctt gaatagtttt ttacaatttg ttcatttttt atttctgtta ttcctatttc
     3481 tattatttca caacctttat atggatctaa tcctgtagtt tctaaatcca caactacata
     3541 ctctttcata tctcttctcc ttattattaa atggatatat ttatattcta tatttatgta
     3601 atagactaat caatacttaa ttttatatga tataggaaga ttttacaaat tacaacatag
     3661 atatatccta tattccatca taaataaaga tttttttatt agaataatta aacttttaat
     3721 ttattgttat ttaatctatt ttgataaaca ttatttattt tattattatt taaatcttta
     3781 aaatctaaac ttttacattg ttcatcatct tcccatattc ctgcttgttt atttccatca
     3841 tttttatata atacaccctt accatttttc ttattatcta aaaaatatcc cttataaatg
     3901 tcattattgg gatatgttaa ttttcccaaa ccatttttta atccgtattt aaattcacct
     3961 gtatatattg aaccatctct ataagtatat tttcctattc catgcatctt gtcatctttc
     4021 cataatcctt catacttttc cttacctgaa aaaatatata ttccaaatcc atttttcttt
     4081 ccatcaacaa actcaccttt atataaatca ccattatcgt atttaaatac tttttcttcc
     4141 tttaatttct tattgttact cttattttta ttattattgt tatcctttat atgtatttct
     4201 tctcttctgg cttcaataaa atctctatca tacctaaatc cgtttcttga tttaattttt
     4261 tgattaatct tcttcttatt aataaatact ctagctagtt gagtaaatat aaatacagat
     4321 gataagcata taaatacaca tagtattgtt gtaaaataac tagttatatt ttccataaaa
     4381 aatcaccctt taaaaaattt atttaaaata cctaatataa tatatatttt tattaaatgt
     4441 tatttatact tttatagtac tatattgaat aaaattaact ttgaaattat ttacattaaa
     4501 ataaatcaag tacaaatgcc ataaattaag tgtttctagt tagcataaaa atacttataa
     4561 agtatactca aatatttcaa ataaatactt ttattcaaat aaatctctac ttatataagt
     4621 gcttatataa ataaaaagat gaactatagt aaatatagtt catctttttt ataatagtat
     4681 ttatttaaaa ttaatattta tttagttagt agcatctact tagatatcag ataagaaagc
     4741 acagtcattt acttataata agttcttttc atatattttt tattataatt attcttttac
     4801 aagaactttt ataatttctg aaatgtacat agtatgatag tctttctctg gataccattt
     4861 tttatcattt tctttagcat caaagttttc tggtggcata ttaccatgat atagcttttt
     4921 acatactata atcatattag cttcttcaaa agctaccgta tcatccacaa aatatggtgt
     4981 aagtcctgct ttttctattt tatttatatc tctaccagaa atagtgccac aaatatttaa
     5041 agcttctcta tacgtttcat caaagaaggc aattgtaaat gtatcattac tatctacaaa
     5101 ttcttttgta tatctctgtg gtcttatgta agttgtaaca acatttttac cccaatagac
     5161 tccaacacca ccccagctag cagtcattgt gttaaacttt tctgaatcac cagctgttat
     5221 aagtaaccat tctttgccaa tcttagtaaa tggattaaac tgtaattcct caatttttac
     5281 ttctctaaaa cccatgactt catcctaccc ttcatttttt aattatataa attaattgtt
     5341 aaaaatttga atatatgtac tcttataata ctgacttttg attgtcctac ataattcatg
     5401 taaattataa tacaacaaat caattacttt cgcaataagt agttttcata ttttataagt
     5461 gtaaaatata gataaaatat attgattata aagtatataa tatattttta aacctaaagc
     5521 aatatacaat aaaaaaatgt agaaagtaag tatctctcta cattttttat tgtatattat
     5581 ttttatatta atttaatttt atcttgattc agttttataa aaaattgtta taattgtcaa
     5641 gttctactct attatttata atttcttata tcttattaac aacatttaag ttattacatt
     5701 tatttatata tattttttca ttatctaagt cttcatcaaa catttttatt atatttttta
     5761 tctcatactt gtactcatct tcattcattc tataaagcat taaatcttct agtacatctt
     5821 tcatatcgaa gtacacatct tctaataaat aaaaatagcc ttcctctata tctttcaatt
     5881 tatctatagt atccattttt ttacttatat ctttcataat ttctaaattt tgtatattta
     5941 catctatgat tgttaataag tacattctca cagtttttat tatttcaaca gaaaaatcta
     6001 caatattata atttccttct tttttatata atgactcctt aaatttgtta aaacaattat
     6061 ctaaattaga atttatatcg ttaaatggtg gtcttattat gtcacgtatt attaaaagat
     6121 tttgtatatc tacattattt gtgattgcct catccaaaat aaataaatta tatgcatcat
     6181 ttaatgggtc atgggcatct ccactaaact ctaagttaac aaattcaagt aaatttttca
     6241 atgatatata gttcatacat ctcataccac aatttatata tttttctttt atatctacaa
     6301 ataaatctct aatgttattt acaaaccttg gatggttatt ttttttagca cttctcatat
     6361 ctgtgttatt gaaacatgtc aaatccaaat taccaaaagt atatattcct ttaatatcag
     6421 aaaatatgcc aagccatttt ttaaactttc tcatgacctc ttcataactt ggtgcactct
     6481 tcaattcttc agaagatata tgtgttaatt cttgtatatg aggatacaac tcctcattac
     6541 ttactggtct tattaaagat ttaaatttat caatattttt tgttttttca tcatacataa
     6601 ctgctccgat tgcaattata tcagaattaa atactgctct ttttgattta gaatttggca
     6661 tattcatttc aaaatctata tatactcttt tcaatataaa caccctttcc aattgtttat
     6721 agtgattctt tttaactatt tttattcaaa attttctaag aaagaatgtt tctccccatc
     6781 tttttgccaa ccaagtactg aatcaagatt tacattttct gccgccttaa atatagattt
     6841 ttctacattt ttaaaatttg attctaagct ctttattaag tcttttatct catatctttt
     6901 attacctgtt tttttagcag caaccataca tgcacaattt aatggccata taccactatt
     6961 ttgaataaat cttataatat gttcttctct tatataataa agtggtctta taatttttat
     7021 accttcaaaa ttagtagaat taagtttagg aagcattgtt ttaaaatttc cagcacacaa
     7081 taaattaagc attgttgtct ctattacatc gtcataatga tgacctaatg caagtttgtt
     7141 acaccctaat tcttctgcct ttgaatataa tgctcctctc ctcattcttg cacacatata
     7201 gcatggataa tcttttgcta tttcatctgc tatctcaaat atccttgaat caaataaatg
     7261 tattggtata tttagatact cacaattatc tataagtaat tgtcttatat ttgcatgata
     7321 tccagggtcc atagcaataa attcaacatc aaaattaact tgtccatgtt tttttaactc
     7381 ttgaaacatt ttagccataa gaatactgtc ttttccacca gaaatcgcta cagctatctt
     7441 atcaccttct tcaaccaatt tataatctct tattgccttc ataaacttag accataaatt
     7501 tttcctatat ttttttatta tacttttttc tatatctctt actggaagtc tttcctcaaa
     7561 aggaactata atttcacagc cttttcctga tagttcactc atctaatcac ctcgtatatt
     7621 tatgttaata atattttaca aaaaagtcta ccttcatcca caaaatacta taatttttac
     7681 tttaatttta ctaaataatt tatagtttac aataacacat aaacttataa taacataaat
     7741 aacctctttc ttttattatc ttttttattt ttctcattta atattttatt attagtaacg
     7801 atttttaaat gattgaatat tatacactag atagagttac ctatctattt acaacaagga
     7861 ggttttcatc ttggaaaata agactagaga tatcaaaaaa aattgtggtc catctttggc
     7921 tagaccatac attaataatc aaattttcac agaaatgtac tgcctttctg atgcattaaa
     7981 atttggaact atatttccag aactaaactt actagagtct gaaatgtaca acaaagaatt
     8041 atatgctaag ccaaaaaaat atagaggagg tagaagataa tgaaagactc atctagagct
     8101 gaacttatga gaaaagttca ggaaacatct tttgcatgtg ttgatatgaa cttatattta
     8161 gacaatcacc ctgatgataa aaatgctatc aacacttata attcattatg taatcaattt
     8221 gcgcaagcta gatatgctta cgaaaataaa tacggtcctt taactaactt tgggtatgct
     8281 ccaagtagat gcccttggca atgggctgac caaccttggc cttgggacag agaatttaat
     8341 tattagacat caagtattgg aggattgaaa attcatgtgg atatatcaga aaactataca
     8401 acacccagtt aatataaaaa cttgtgaccc tagaatggct aaatttctta taactcaatt
     8461 tggtgggcca aatggagaac ttgctgcatc tttaagatat ttaagccaaa gatatacaat
     8521 gcctactggt aatatgcgtg cacttttaac agatattggt acagaagaac tagctcacgt
     8581 tgagcttata tgtactatgg tttatcagtt aacttctgat gcaagcccag aagagttaaa
     8641 agctgcaggt cttggttcaa actatgctca aaatggatat ggaatttatc caacagattc
     8701 aaatggtgtt ccatttgatg taagacctat agcagttatg tcaaatcccg taaccgattt
     8761 acatgaggat atggcagctg aacaaaaagc acttgcaact tattatcaac ttataaacct
     8821 aacagatgac gttgatgtta tagatgtatt aaaattcttg ggtcaaagag aaataattca
     8881 ttatcaaaga tttggtgaag ccttaatgga tgcttacgag ttagaagaat ctcaaaaaat
     8941 gttctaaaat ttttatttgt ataactatta ttatttgata atttataatt tactgttgtg
     9001 ttaaaattta taaaaaatat aaatataatt tattttctat aaacagagaa aataaataaa
     9061 aagcaggtat caatcaaata gtaacatgta ttatactata cattactatc aatattgtac
     9121 ctgctttcat attataagca ataaagaaaa atctatttat taggttttat aataaaaaca
     9181 attataaaac tcttcttgca tttacatatc tacttgaata gtagctacta tttatattag
     9241 atattgttac tttttttgat gaacctgaag atgcatgtat catatctcca tttcctatgt
     9301 atattccaac atgacttaca gaaccattat ttgaaccttg tgtatcaaag aatactaaat
     9361 ctccacttct aaggtctcct ctatttacat atgttccata cttactttgg tctctagata
     9421 ctcttggtat actaactcct acagattttt tcataacgta ctgcgtgaat ccagaacagt
     9481 caaaactatt tggaccttct gctccccata catatggttt tccaagtagt gtctttgcaa
     9541 aacttattac actatcagct ccttgacttg gagaattagt cgaataagat ggaattgaag
     9601 tatcaacaga acctttttca gcaaggtatt gacttgacac atatccagtt tgattgccat
     9661 aacttatttt tgtccatcct ccactttcag aaatacttcc aacctcagta ccataactta
     9721 atgtagctat tttagaatga cttgtacctg gtcctgttct aacgttcaat gactttgctg
     9781 ttacaacctt tgtacccttt acaaggtcat ttgaactgtt ttcagcattt tcatttgtag
     9841 agtcatttac actagttcct aaatatttac ttgaaacata acctactcta ccattagaac
     9901 ttatttttga ccatccattt gactcagata tgtatccgac ttcagtccca tatcctagtg
     9961 ttgatatttt agaactactt gtacttggtc ctgttctaaa atttaatcct tttgctgtta
    10021 caacttttgt cgacttaact gaagtatcac tactttcatt gctacttcca aggctattta
    10081 ttgctacata atttccatgc acataacctg tgtttccatt atatttaact tttacccaag
    10141 aaccttcttt tcctacgtac tcaactttat cacctttgta aagtttcccc attgattcat
    10201 ggtttgtacc tggtcctttt ctaaaattta ccgcattccc tgttattgtt ctgctttcta
    10261 tactcacact ctctacttca gactcattag catatgctaa attccccata gtaggcatta
    10321 ttatcgcagt tgccattata ctggctgcta ttctcttttg attaaaattc ataactttcc
    10381 actcatctcc tcttttctac tatctttatt tcacttcaaa atataaaaga aataattgac
    10441 actatcaaaa tatcaattat ttcttttata ttaatattat tacaaatttg taactatttg
    10501 tctatagtaa tatttgctta ccataaatta ccatgtataa attttaatct ttaatagcct
    10561 gtaatttagt aatatagcca tcttttacct tttttaaaaa tggctatatt ttttaacttt
    10621 tttgtaactt tttaaaatcc agttgagcca aacccacctt ttcctctttc ggagtcactt
    10681 aattctttta cttcttctat gttaatatca tagataggtt ttactatcat ttgagcaatt
    10741 ttcatatgct tttcaacctt aaaatcattt ttaccatgat ttattaatat aattttaagc
    10801 tctcctctgt atccttcgtc aatagttcct ggtgtattta atacagtaac agaatgcttt
    10861 aaggcaagcc cacttctagg tcttacctgc gcttctgtca tagtaggaag ctctatacat
    10921 atcccagttt tgataagttt agtctctcca ggaggtatta caacctcttc tatagaatac
    10981 aaatccatac cagcatcacc tttgtgagca aaattaggta ttatagcatc atcatttaat
    11041 ttttttactt ttaaattgta catcttatat ctcctttcaa ctttctataa atattataac
    11101 ttaaatttcg acctcttgaa gttttttatt tttttgtggt aatataatta ttagtgtttt
    11161 aaaggaggat tttttatgaa acttgtactt gctgagaaac catctgtggc aaaaactata
    11221 gcatcatttt taggtgcaaa gaccagacaa gatggttact ttgaaggaaa tgattatata
    11281 attacttatg cagttggaca cttagtatca ttatatgata tgaaggatta tgataaagat
    11341 aaatactctg gctcttggaa aatgaacaat ttcccatttg ttcctgagga taagtttaaa
    11401 tttaagattg atagttctaa aactaaacaa ttcaacactg taaaaaagct tttgaataga
    11461 aaagatgtag aatatgtaat aaatgccact gataatgacc gagaaggaga acttatagca
    11521 tttttaatat ttttactggc aaaaaataaa aaaccagtaa aaagaatctt ggtaaatgaa
    11581 tggacaccag aagatattac aagaggtata aaaaacctaa aagatgaaga tgaaatgaga
    11641 aatcttcaag ctgctggata tactaggctt attactgact ggttgattgg aataaatttc
    11701 acttctgttg ctacattgaa atacggaaat gggaaactat taaacatagg tagggtaatt
    11761 cttccaacag ttaaattagt ctatgataga gatatggaaa tactaaactt tgttcctaaa
    11821 acttattatg aaatagaagg gcattttaaa gctgaagctg gtgaatataa aggtaaatat
    11881 gttaagggta aagaaagtaa atttgataca cttgaagatg caaataaaat tatagcttca
    11941 attacatctg aaactggtaa aatactagat aaaaaagtta ctatgtcaaa ggaatatgca
    12001 ccaaaacttt ttagtttgac atcacttcaa ggatatataa cttctaagta ttccaatttt
    12061 acatctgata aggttttaaa tgtctgtcaa tctctctatg agggtaatgg taagggtgga
    12121 tacataactt accctagaac tgattccatt ttcttagaag aaagtttggc ttcaaaagct
    12181 tctcaaactt tagataaatt aaaggttggt cttgaatatg aaaataaaat taaattttct
    12241 aaaactaaaa gagtttttga ttcttctaaa gtagactccc atagtgctat aattccaact
    12301 tatataattc caaaaagttt atctaaggat gaacaattag tttatgatgc cataaaagat
    12361 agatttgtag caaactttat gcctcctgct gaatatgaga atacagaaat taagactgaa
    12421 gtagataatt gtactttctt aacaaaaggt aaggtgctta aatcaaaagg ataccttgag
    12481 gtatataata aggaagaaaa aaacgattta cttccacttg taaataaaga tgatgttgta
    12541 gatgtgttag aaataaaacc attaactaag caaactactc cacctaaacc gtatactgag
    12601 gacacacttt taaaggctat gaaaaattgt ggtaaaaatg tgcctgaaga agatacaaca
    12661 gtgctatctg gatattcgat tggaacatca gccacacgtg ctgatgtgtt aaagaagata
    12721 agtcaagtgg gctatgtaaa gaaaaaaggt aaatcttatt ctataacaga ccttgggaaa
    12781 aatttagttg aaatttttcc tgttaaagac ttatttgatg tagattatac tggaaaactt
    12841 gaaaaaagtt taagcgatat tcaaaaagga aagtatacaa gaaaagaata tcttactaat
    12901 atcattagtt ttatatatca aaatgtcaat attataaaac aagatgcttc aaaaaatata
    12961 aacacagaag catatacttt cgattcaaaa actaaaaaat ttactaaaac aaaagaaaaa
    13021 aaacagaaaa aagatgtaac taatactgaa aaagaagttg ctatatcaaa ggattctaat
    13081 aacaaaaaag aagttaaaaa tggtgatgaa aatcaatctc ttggcaaatg ccccatttgt
    13141 caaggtgatg tactagaatt tgacaaaggc tttgcttgta aaaatcataa agaatgtaaa
    13201 tttgttattt ggaaaaatga taagtattta agtctttata aaaagaaagt taacaaaaca
    13261 atggtcaaaa atattttaaa aaaaggtgaa actaaagtaa aatctttaac tgctaaaaac
    13321 ggtaataaat ttgatgctac attaaaatat gataaaaatc cagatactgg ctatttcaat
    13381 tggaaaatag agtttgacaa ctaaatattc ataagaaaag aaatagcagt agtataataa
    13441 tctatattat attactgcta tttcttttct tatgaagttt caactttttt aatagtgact
    13501 tttacaatca cactctaacc taatttcttt actatttctg ataactttaa tgtatgttca
    13561 tctaataaag ttagttcctc ttcagaaaga ttagataatt tttttactag agattctttg
    13621 agaatagctt ttactgcatc aaataattta aatgctttat ctgttaattc aaccctaaga
    13681 atccttctat cttttgggtc aggaaattta ttgactaaac catgttccac taatctgtca
    13741 ataatcggag tcatatttga ttttaaaatt cctaaattag aagctatttg agaaattgat
    13801 gatgaatttg atgtcataag ataaagaatt accttagcat gtgatggagc cattggacat
    13861 tcttcaaaat aagctttcat tatatcagag ttattttgaa acttttttaa caaatcgctt
    13921 tctttaaata tattattttc aagcacaaat aaaaaatcta aaaaagagtc cgctatttta
    13981 agtatattgt tgttatccat atttgtaaca tcccttcaat agataatata ataaaacatt
    14041 gttgtttaat atagtataaa ttataaacta ttaataaatt taaaacaaga aaaagttatt
    14101 gactcataat aattataaat ttataatcaa attagagaat tataaattgc caataaaggg
    14161 aagtttttta attagtctaa aactaaactt aaattataag acactttaaa ttctacaaca
    14221 agctagtgtg caatatataa taggaggaga tatgaaaaga tatttaatag ttttcttaat
    14281 gtgtagttca ctgtttttag ttggatgtgg aaaaacagaa gaatctgaac ctgagaaacc
    14341 aatagcagtt tctgttcaaa aagcaatagg tggagaaatt gaaaacacaa attctttctc
    14401 aggaactaca aaggttaaag atgaaacagc tgttactgca cagactgttg gcacagttca
    14461 agaagtgtat gtaaaacttg ggcaaaatgt aagaaaagga gatgaattat tgagtataag
    14521 cagtccagag ctagaaaata gtgtaaagca aagtaaagcc tcactagatt tagcaaaagc
    14581 aagttattca agtgccactg gtggttcatt agaggcacaa gtaaatcagg caaaaacagc
    14641 tcttgacaat gcaaagattc aatatgagga gtctcaaaga aattatgaca ataataagat
    14701 tctttatgaa caggaagtca ttagtttaga ccaatttaaa aaaatagaat tttctttaga
    14761 gcaaacaaaa caacagttag attctgctca aagagcatac gatacagcaa cttcaaaaag
    14821 tatacctcaa gctaaagcac ttgctaaaaa acagcttgac caagctcaag tatcatataa
    14881 tttagcaatg agtaatttag acaaattaac attaacatct ccagtagatg gtacaataac
    14941 agctaaaaac tttgattcaa aggaaatgat aacacaatca caaccagctt ttattatttc
    15001 taatcctaat atactagaag ttgatttaaa tgtagcagaa tcagatatag gtaaatttaa
    15061 gaaagatgga aatgtagatg ttataattga agaccaaagg attttaggaa aaatagatta
    15121 tgtaccttca gtagttgacc ctcagacatc tttatatcct gttaaagtac ttgtaaataa
    15181 tacaaacaac aaatttaagg caggtatgtc tgctcaagta aacttaagtg ttgaaaaaga
    15241 aaatggtgct gttacagtac ctaaaaaagc aatatttgaa gaaaatggta aaaaatatgt
    15301 atacatagca acaaaagaca atatagcaaa gaaacacttg gttcaaactg gaattgtaac
    15361 agaggataaa atagaaatta aaagtggtgt aagtgataaa gatacagtga ttatcggagg
    15421 gataagtctt atttctgacg gaactaagat atttcctgta gaaaaggaga agtagactat
    15481 gaatttaaca cagacttccg ttaaacgtcc tctcacaatc ataatggtct ttttagtatt
    15541 aatagttttt ggtggtattg gatataaaaa aatgtcaata aatctaatgc ctgatataga
    15601 aataccagtt gtaatggtca tgactacttg gacaggtgct ggtcctcaag acgttgatga
    15661 acaagttagt caaaaagttg atgaaagttt atctgccgtt tcaaatgtaa aatctactat
    15721 atcaagttca caagaaagtg tttctatggt agttgctcag tttgaatttg gaactaattt
    15781 ggatgaaata atgaatgatg ttaggtctaa agttgatgca ttacagacca gcctcccaga
    15841 tgatgcagct aaaccaacag ttttaaagct ggatatgaat gcacaggcta taggtcaact
    15901 tgtcatatct ggaggaaatg aaaatagttc acaagcctta agaaaatacg ctgaagatgt
    15961 aattcagcct aaaatagaat ccatagatgg tgttacttca gcagacctta aaggtggaga
    16021 aaaagcacag gttaatgtaa tagctgaccc agctgttctt tcaaattatg gagttagttt
    16081 atccactata aaaggtgtct tatcctctag taataaaaca ttcccttatg gttcaattac
    16141 tcaaggtgag gataaaatag ttttaagagc gattgataaa ttagaatccc tagatgatat
    16201 aaaacagatt caaattcctg taaaaggagg aaatacagtt agattagata atctttgtag
    16261 tgtagattat ggatatgcag acaaagatag tatttataga tacaatggaa aagacagttt
    16321 ggtaatagat atttctaaac aacaagatgc caacactgta aaagttatgc agagtgcata
    16381 caaatacgta gatgaattga ataaggaaaa tcctcaattt aaaattaaaa ttgctaatga
    16441 tacaagttca tacataagtg aatcaataaa cagtgtaatg agcaacttgc ttataagtgc
    16501 tgttatcgca tttattgtaa tatttgcttt cctaaaaagt gtaagagctt cactagttgt
    16561 tgcagttgca ataccaattt ctataatagg tgctatagca attctctact ttactggtga
    16621 aagtttaaat cttattactg caagttcatt ggtaatttca gttggtatgg ttgttgataa
    16681 tgctacagtt gtaattgaaa atatatttaa atataggaaa agtggtagat tgagtcttga
    16741 tgattgtgct attgagggaa caagaactgt aacaaatgca atacttgcat caacattgac
    16801 cacaatagca atattcttac ctatcatgtt tacagaaggt atagctaaaa taacttttgg
    16861 ggcattaggt aaaacactaa tagcttcact agcattctcc tttataggtg caattacact
    16921 cgttcctagt gtatttgcaa aattaagcag aggaaaaaat agtcaaaaga tgcaagaaaa
    16981 agatagtcct atatttgata aggtaagtga agcatataaa aaattattaa gtgtatgttt
    17041 gagacatcaa cgcttagttg taatatcaag tttacttatt tttgtagctt ccttatttgg
    17101 aatgggattt ataggtatgg actttatgcc tgcagcagac aagggtgaat tatctatttc
    17161 tatagaactt ccaaaaggtc ttagcctaga atccaatgat tactatgtat ctatgactga
    17221 gaaaaaagtc tcagatattc cagaaattaa aactttaata acaactttga catcagattc
    17281 aaataatagt aaagcaagta tagcaattga attagaatct caaaaaaata gaaaaagaac
    17341 tactgatgaa atagaaaaag agataattga tagagtggct actgtaccag attgtaaaat
    17401 aaatgtaagt caaaacagta gtgttatggg tggagctgga ggagcagact tcacattaga
    17461 aatgaaaggt cctgatttag atgtattaaa aatactggga aaagaagctg aaaaagaatt
    17521 tagctctata aaaggattta gaaatgttga aacttctctt acagatacaa cacaagaagc
    17581 tcaatttact atagataaac ataaggctca agaatatggt gtaaataccg ctgaaattgc
    17641 aggcatgtta cgtacagcaa taaatggtga ctccgtaacc actgctacta ttgatgatta
    17701 caaagtggat gtaaacctaa aatttaaagc agatactatt gatagcttag aagatataaa
    17761 gcaactaaaa gtaaactctg caactggaaa agaagttcct cttggtgcct tttcagatat
    17821 aaaaatggca gatggtctac aatctatatc taggactgat ggagattttt ctgtaaatat
    17881 aactgctaca cttgacaatt tagatgctgg tactgctaca aaactagcac tagaaaaaac
    17941 gaataaaatg gtaattccta aagattactc tataggtgtt ggtggtgaaa cagaaatgat
    18001 gaatgaatct atggcaagtc ttggattttc aatggtcata gctatagcat tagtttatat
    18061 ggtaatggta gctcagtttg aatcatttag taaaccattt ataatcatgt tctgtgttcc
    18121 atttgcattc gttggagttg tgctttcgct tctagttagt ggtcaaagtt taagtactgt
    18181 cggtatgcta ggtataatct tacttatcgg tattgttgtt aataatggta tagttcttat
    18241 tgactacata gagcaactta gaaaaacaaa tcgtaacaat gatttaattg gtttggtttc
    18301 aattggttgt gcagcaagat taagaccagt cttaatgact acagcaacaa caattttagg
    18361 tatgttgcca acagcactat ctcttggtga aggtggagaa actatgcaac cactagccat
    18421 agttataatg ggtggtctaa ctgtatctac acttataact ttggtgctta tacctactat
    18481 atacttaata tttgataaat gggaaaataa gttttcagac aaaatgccta aaatatttgg
    18541 taagataaca gataaaatag gaagtataaa acgtaaaata ataaagaaac caaaattgaa
    18601 agctaaagtt taaatagaat ggagggtgat tgtattgaat aaaaaaatga gcaaaatagt
    18661 tgcaattagc tgtggtgttg gtataataac tgccaattta atcccagttt acgcagataa
    18721 taatacttct tctataaaca aagttgataa ttctatttta agtgactcaa ataaaagaac
    18781 atctgaaaag gaaattttga ctgctagaga agctgttagt gctgcactta aaaatagtga
    18841 aaaattaaaa atgaaatcag aagaaataaa aatgttaaaa gaaaagttag aagtacaaga
    18901 tgagtttgat agttttactg gaagtgacaa ctcgtttcca tacgaccaaa ttggacttct
    18961 taaaaatcaa agtgaacagg ctaaaggctt tatggaggac caaatagcaa atgatattac
    19021 taataaattt aacgatttag tttcaagaga aaatgagcta gataaaataa aaaacaatct
    19081 tgaaataaaa actaaagaaa ttaaagatat gaaattaaaa aaagatttag ggttagtaac
    19141 atctttagaa actgaatcag ctgaacttga acttcaaaca ctacaaaata ctcaaaaagc
    19201 taaacttcaa gaactaaaaa acaatcaaga ctattttaag ttattaacta atatagattt
    19261 aaataattat caattggata aagaatatag atttgaatct tttagagtag gtggctcagt
    19321 tgattcatat atggaaggta aggttaatga atatttaaaa tacgaccaat tgattttaga
    19381 acgtacagaa gaaagcttta atgataaaga tgagaacaaa gcagatttac cagatagacc
    19441 taaccttaca agaccagttg ctcctacaaa accagagcaa ggtaacctaa ctgatgatga
    19501 atacaaggtt cttatggata agtatgaaaa agattatgat agatataaaa aagaagttga
    19561 agcatacaat cttgaaagac agacttatgc tgctggcctt actacttatg caaattatct
    19621 tcaacaaaaa tttaatactg aaaatggtct agtaacatta gaagacagta aaaaagctct
    19681 taaaaaaggg ttaattgata gctatgctca attacttgct ttagaagata caattcagat
    19741 tactaaaaaa caacttgatt tatcagaaaa acaattaaaa aatactaaat taagatatga
    19801 tttaggatta attactctaa ctgattataa aaaacaagtg gtaagtaatg aagatgctaa
    19861 aaatagctat gacactctta ttgtgaatta taactcacta aaaaatggta tagaaaaacc
    19921 ttggatactt aatactggaa aataattctg gtaaatagaa agattacttt aacatacgtt
    19981 tgattaaaaa atagttatgc atactcgtgg ctttagtcat ggaagattca gaaggcaaat
    20041 aatagaaata gattagtaaa aatatattta cttataaaac tgtatacttt tatagaggct
    20101 atctcaaaat agagataagc ctctttttta ttgtttaaat tataaaaata tatttgattc
    20161 catacaaaaa gagtgccttc tgaactaaaa agttcatttt gagacaccct caaaagctta
    20221 actctaaatt taattatttt ttatcaaatg tttcatctat tttacatctc accatgttaa
    20281 caaattcaga aatattatat cctctaagtt tgcatccaca tttaggacaa taatccagtt
    20341 tcctagatac caaagcccta caactaggtt ctggacatct tatttttaga ctctcatctg
    20401 ctactttaaa tccacatcgt gggcatatac tacctggacg tgatgatact tcctttccac
    20461 atttaggaca ctttgtcaac tttatcccct ccagtaaact caatttaatt gatagttgaa
    20521 atttctctct acaataatat atgcaatata attaaatacg tttcacttac aactatataa
    20581 gttaaatttt tataataaaa atcccctata ttcaatttac aaatacttaa tttgatacat
    20641 tgaacaatag gggattttat ttttatttag ttacatattt tgcagtctat tattatctag
    20701 gattttttat agatgcttga gctgctgcaa gtctagcaat tggcactcta aatggtgaac
    20761 aagatacata gttaagtcct acactataac agaactctac tgaagatggt tctcctccat
    20821 gctctccaca tattcctagt tttaattctg gtttaacttc tctacctaat ttagctccca
    20881 tcttaactaa cttaccaaca ccattttggt ctagtacttg gaatgggtct ttttctaata
    20941 tttcttcatc tacatattga cctaagaatt taccagcatc atctcttgaa tatccaaatg
    21001 ccatttgagt taagtcatta gtaccaaaac tgaagaagtc tgcttcttgt gctatttcat
    21061 cagcagttaa acaagctcta ggtatttcta tcatagtacc tacagtataa ggaacttcta
    21121 taccttcttc ttttattata gcgtcaacag tttctactat catttttctt attattttta
    21181 actcatttac ttctccaact aatggaacca ttatctctgg agaaacttta acacctgctt
    21241 tgattgcttc tatagcacct tgtattatag ctttagattg cattacacat atttcaggat
    21301 aagttattgc aagtctacaa cctctgtgtc caagcattgg gttaaactca tctaaatcaa
    21361 ctattctctt cttaatatca cttactttta ttcccataga ttttgaaagt tcttctatag
    21421 tctcatcatc atgaggcaaa aattcatgta gtggtgggtc tagtaatctt atattaactg
    21481 gttttccatc cataacttta aataactcta caaaatcctc tctttgcatt ggtaatattt
    21541 tttcaagagc tttttctctt tgttctactg tattagataa tatcatttct ctaactgctg
    21601 gcaatctagc ttcatcaaag aacatatgct cagttctaca tagacctata ccttctgcac
    21661 caaactctat agctgcacga gcatctctag gattatctgc attagttcta accatcatac
    21721 atttgtgttt gtctacccag ttcattaatt tttcaaaatt tccagttaaa gatacttctg
    21781 ttttcttaac atctcctagg tacacatttc ctgtagaacc atctatagaa atgtattctc
    21841 cttcttttat aactacatca tcaagtgctc ttatttcttt attaaactca tcaactttta
    21901 tttctccaca tccagcaaca caacatttac ccatacctct agcaacaact gctgcatgtg
    21961 acgtcattcc acctctagct gtaaggattc cttctgcttt aaccattcct tctatatctt
    22021 ctggagatgt ctctagtcta actaaaacta ctttttctcc tttttcattt gcttttacta
    22081 catcatcagc attgaaataa actttaccac ttgctgcacc tggtgatgct ggtaaacctt
    22141 ttgctataac cttggcttct tttaatgcct tatcttcaaa ttttggatgt aataattggt
    22201 ctaattgatt aggctcaatt ctcatgatag cctctttttc atcaattatt ccagcttcaa
    22261 ctaaatcaac cgctacattt attgctgctg ctgctgttct cttaccattt ctagtttgta
    22321 gtatatataa tctttcattt tctatagtaa actctatatc ttgcatatct ttataatgac
    22381 cttcaagtat atgagtaatt tttacaaatt catcgaatac agctggcatt acatctgcaa
    22441 gagttgatat attttgagga gttcttatac ctgcaacaac gtcttcacct tgtgcattca
    22501 ttaaaaattc accaaataat ttattttctc ctgtagctgg atttctagta aatgcaacac
    22561 ctgtaccact agtttctccc atattaccaa ataccattga ttgaatattt actgctgttc
    22621 ctaagttatg agctatatca ttcaatttac ggtatacgat tgcacgagga ttattccatg
    22681 atctaaatac agcctctatt gcaagcatta attgctcttt tgggtcttgt gggaaatcat
    22741 tttttatttc ttttttataa attgctttaa attcttttac tatttctttt aaatcatcag
    22801 ttgtaagttc tgtatcaact gtgtatccct ttgcttcttt tactctgtct aatacatttt
    22861 caaatttata ttttggaact tccatagcaa catcagaaaa catttgtatg aatcttctgt
    22921 aactatcata tgcaaatctt tcattttgtg tagcctctgc taagccaaca acactattgt
    22981 cattaagacc taggttaaga attgtatcca tcattcctgg catagagaat actgcaccag
    23041 aacgaactga tactaataat ggattcttat tgcatcctaa tgttttattt aagtcttttt
    23101 ctaaagtagc taaatgctct tctatttctt ttattatctc tgctcttata ctttcattgt
    23161 taacataata atcattacat gcttctgttg ttatagtgaa tccaggaggg acaggtaagc
    23221 ctatcttagt catttctgct aaattggcac ctttacctcc tagtaaagat ttcatgtctt
    23281 tgcttccttc accaaaacta taaacatact tagtttccat tgttaaatcc cccattaatc
    23341 tttttatttt aatttatatc atttttatta atagacatta ttaaatttct atttctttgt
    23401 atatctttag accattttct ttcattatgt ctaaaattat acctgctgtt tcttctattg
    23461 ccttatttga aacgtttatt actgggcatc caattctttt cattatctct tctgaataat
    23521 ctaactcctg aagtattctt tctaaattag cgtagtttgc tttactggac aatcctaaag
    23581 cttttaatct ttgggttctt atctcattca gcttttcagg tgaattagta agacctatta
    23641 tttttttagt atctatctca aacacttctt taggaattgg tatttctgga actaatggaa
    23701 cattagctac ttttatattt ttattagcta aatacatact caaaggagtt ttagatgttc
    23761 ttgatattcc cactaaaatt atgtctgctt gaagaacacc tctagggtct tttccatcat
    23821 catatttcac tgcaaattct atagcttcaa ctctcttaaa gtaagattca tctaattttc
    23881 taattatacc agcttctctt ttaggttttc ttcctgttct cttgcttatt tctcttagta
    23941 tatctgtcat taaatctata caactaagac cttctctttc gcaatatctt tcaacaatac
    24001 tgcataattc ttcatcaact aatgtatata caattaaagc gttttcagct tttgcattct
    24061 ccaaagtttc aagtagtact cctttattaa tcatgtatgg aaatcttttt atttcataag
    24121 tttcattcac ataaaactga gacatacatg cctttgcaac ttgttgtgca gtctccccta
    24181 ctgaatctga tactgcatat ataattaggt ttttcaccag catacctcct taattgtcaa
    24241 ctatttctaa gaatagctta gttatgttgg tttttgatat tctcccaaca actctcatat
    24301 gatttttgtc ttctccctta tattcaacaa tcggaatcga atctacttca tgttctatta
    24361 tttttcttga agctaataaa acacttgctc ctttagttaa agtgactaca tttggagttc
    24421 ttgtcattat catacctatt ggcattttat ttatatcaga acctcctata gttgctttta
    24481 gcaagtcttt tctggaaaca actccacata actcttcatt ctcatctata ataactatac
    24541 tccctacatc agataaaaac atagtgacta ttacatcata tatactttca tccttcttag
    24601 ctagtacagg catgctcatt atatcctcta ctgttttttc ttttacactt ttaccaatta
    24661 aatttatttc actaactcct gaataaaaat atccaacttt tggtcttgcg tctaatattc
    24721 ctgtcattgt taatatagct aaatcagatc taagtgtagc acgagtcaca ttcaagctgg
    24781 aggcaatact ttcactcgtt attggttcat tttccttaac tatatctata atttttagtt
    24841 gtctttcatt aagctgaata ataatcacct tctttcattg tgctatactt tttatctttt
    24901 cgcatcttat atagtatatt atataactat atataccatt ctgtaaacag attttttatt
    24961 gaatacgata tattttttac taagttctct cgcttaaaga tatttattat atattaatgg
    25021 gggatatttc tttaattaat agaactatat tagtattaca gttaatatta taatacataa
    25081 ttggtcattt taattcattt tatattaaaa tttttaataa tattatttca atgtgaatat
    25141 aaaattgcag aactaattca aaataatttt tacgactaca aataacctat aatatacttt
    25201 taaagaaagt atcctaacaa gaatatataa aaatttaaaa gggttgattt aaaaataacc
    25261 atcaaccctt tttactaata tctatttata ttaccatcaa atcttaccca aatatttttt
    25321 cttgcaattg tcttaaatga tataaagtag tatctttttc tatctctacc atatcgtaag
    25381 ttataacttc acctttttta atatctttta caactttagt ctttttactt atcaaaccaa
    25441 taggtacagc attcatagcc tttgctacat cgtatttttc tatagtacca tagcatgtat
    25501 atgctccata gccatccata aactcacctt ttttcaaatc tttcttagct atagtcataa
    25561 cttctgctac tagtccagct ttaggtacta ttgtagcctt atggtctaag actgccatag
    25621 ctgctgataa aggagtctct aaactacata aatgatatgg tctatataat atgtaattag
    25681 gtccatcacc catacttaaa tattttagtt catcattaac tgcttttaat ttatgggcta
    25741 ctactacgaa aactccaggt gctataccat ttacaaaatc aactacacca taattatcta
    25801 atactccacc ttcgcttttt aatgcatatt tcttaggtac ttcattaact gtagcttcaa
    25861 taccatgacc acctcttaca tcaggcacaa atccagttgc attacacatt aaagccattt
    25921 ctaccattgt tttagttcct tctttaaaag aagctatcat atgaggtgaa gctccttttc
    25981 tttctgcttc ttctctaact gtatcaggat tacaatctaa atctaattta ttatttttac
    26041 ctttacctat cactctaact tcaaacccca ttgcatctgc aaaatcaaat aattccatta
    26101 ctgcacctgg ctcatctcct gcagaacctg taaatattac tccagcatca tctgctaatt
    26161 ttttaagtat tggtccaaca acacaatcag tttcagcatt taacataact atatgttttt
    26221 tatttaaaat agagtttaat gctatctctg caccaattgc aatacctcca gttgcatcta
    26281 taactacatc tattgactta gttttacaag ccacaagaaa atcattacat gtcaatactt
    26341 ttccttcttg taattttatt tctgcatcct tttcatttgt tacattatct ataatttctt
    26401 catctattcc tgcatcagta aaagctttat gagccaactc caaatttata tctacaacaa
    26461 tagaagcttc aatacctttc atatttgcca tttggcttac cattccattt cccatatgcc
    26521 cagctcctat aagagctact tttatttttt taccttcctc ttccaatttt gcaagttttc
    26581 tgtttaaatc taacatacca attcctcctg ttataataat tttattttca aattaagaaa
    26641 tagttattaa atctccaata gttatatctg gatttcctat ttccacatgt atttctcctg
    26701 gtaaatttac ttcacatttt ccatcaaatt tgattgtaca atgcccaatt tctctaagag
    26761 tcttctgagc aatatcacca actgaaacta tacaataatc tctattccct atagtaagtg
    26821 tatctcctat ttcaacatca ctttttaacg ttgctattga atgaattaca gatatatcct
    26881 ttaagtcgtc atcattaatg gtttcatcat atataataag acaattgctt tcatccatta
    26941 actctttaac taaactgcct atcccactta tcttaacttc atatttcatg acattcctcc
    27001 tgataattta tatttatatt gagttaatta aaagaaacat ttattttttc ttttataaat
    27061 tttatagctt gtacaatact ctcttcatct ttaaattttt gctctgcact atatatatct
    27121 aatccttcta tttcttcaat ctctttaaat ttagccatta ctgtacgtcc ttttaaaatt
    27181 tctccaaact ttataaaccc atctgaatct gaagatataa tggctatact tcctttagaa
    27241 aaatagcttt tctttttgcc tgtagacact atatcaccct tttttttagc tctatttaaa
    27301 gttttaaaat acaatttatt ctgcttcatt ataaatatag tatttaaaat ataagcaaca
    27361 aataaaatca ctaataattt catatttata caccttccaa aaatcacatt atttttaaat
    27421 ctgtataaca actataaatg ctgtacaata gttatataag gtttttaagt aacacctttt
    27481 taaattctaa aaaagttcta catttactta tcttattcgt taattttaca tcttggccta
    27541 tctttaaaac ttcttcataa atttttacta ataagtctga gtctatctta ttctcacatg
    27601 gaaacattgt cataagaatt atttttatac ttctatttgc atattctatt ggttcttcta
    27661 aaattccaac tgccattaaa aacttatctg atttttcatt tacagaatga ggaaataata
    27721 aacctttatc aaatactgtg ggagattttt cttctctatt gactatattt tttctaaact
    27781 tatcatcaat gcatcctaaa tccataagat ggtccatcat tttttctaat gaagcaagta
    27841 tagtcttttc atttaatatc ataaatttat cttcatctaa caaattattt attagtaaat
    27901 ttgtagaatt agtagtgtca atattccctt ctcttaggca caatactgtt tttaattgtt
    27961 ctcttagttt gttttcatca aatattgtat ttatttttaa tactattgta tttatatttg
    28021 atgtgtctaa atcaatagtt gtaaaaacta tatcatattc atctaagtta atatttctca
    28081 aattaaaact tgaaagagta tcaattttag gattatttcc tatcagtttt tctactctta
    28141 ttttcaatag ttttgctgtt cctagacctg tactacatat aattgctatt ttttttattg
    28201 aatagaatct actgctattt ctttctaaat atccactgaa atggattgct atatatccaa
    28261 tctcatcttc tgaaacttct aagttatact ttttctctat tacttttcct gctatttgtg
    28321 ctaatttaaa tggaagtata taattttgct taatctcttc taacaaaaca ttttttaact
    28381 ttatattaaa taatagcctg tttaaagtaa aactaagatg atatcctaga cctactctta
    28441 attcatcctc atttataaaa atacccatat cgacatatat ttgattaaat atattttcca
    28501 tcaactcatc aatgttttta ctaattctac tactatttaa agcacattct gatgctggtg
    28561 catttccact aactaacggt atagttaaat aaataatttc ttcatcattt aaagtacatt
    28621 caaacattcc tgatattata tgttttattt ccctagcaat aaagtattca tcatatgatt
    28681 taagtaaatc aaactttaca tcataatctt ttactttctt ttcttctttt actctataga
    28741 ctaaaactac tatgtagtta ataacttctc ttaacatttc atctgtaaca taaaaattat
    28801 tttttttaaa taaagtcaat agtttttctt ctaaatttat gatttcttct tttttgattc
    28861 ctttaaaata ctttgaatta ctgaaatctt tccttgagtt tttatacaac tgatttaata
    28921 taaacagtct aatatcaagt tcatttccat ttaatttcat acctgtattc tgttttttaa
    28981 tcaagtttaa attatatgaa gccaaaactt tttctacata ctggaaatca tttactaaag
    29041 tagttcttcc tacacacatc tcatcagcta aactatcaag tgtaataaat ccatctagtt
    29101 ctatcaagta atttagtata aactctactc tatcttcttt tgaatttaat gaaaatacat
    29161 tttttctatt catatcaata atcttattga gtatctgctc atcttttatt tctagtttat
    29221 agccttgacc ctttatatat ttgattactg ctatatcatt acctaaatct ttattcaatt
    29281 gttttatata cgtccttaca cttctagttg tgacattcaa ttcatttgct attgagttaa
    29341 tactcacaaa ctctttttta ctacacataa tcaatatctt aaatatcttg cggtcaatag
    29401 aaggaatttt ctcagttaca ctcattttgt atctcctcct tgatttcatt ctagtacaaa
    29461 tttgaaacca aattaataca taaaatttca ctttaataaa ggaaaattta gtattaatct
    29521 aactcgataa ttacagctaa ttaatagtat aaaagctagt ctttcattaa caaaaaatct
    29581 tgactagctt aaatttatat ttacaatttt attaattaat tccaagcctt atattgacat
    29641 taaatattat ctcaatgcaa atactgcaac tccatatgca ataataacag ctattggacc
    29701 agttattaaa cgagagtaaa ataaagctgg aacaccatac tctacagttt ctggttctgc
    29761 ttctcccaaa cttaatccta ctggtacaaa atcacatcca gcttgcccat ttattgcaaa
    29821 taaagctgga agtgctaaat atgctggtat tgcaccaaga ccaatttgtg tacctacaag
    29881 agtccctact acttgagcta taactgcacc aggtcctagt attggtgata agaatggaag
    29941 tgtgcaaatt actgatataa tcaataatcc accaatatta cctgcaagtg gagatataac
    30001 tcttgcaatc cagtctccca gtccagatgc taaaataatt cccataagca tacttacaaa
    30061 tgccataaat ggtattacgt tattcattac catttggata gtatctcgac ctgcatcata
    30121 aaattttgat actacttgcc ctgccccttg accaatagaa agtattatgt tctttttagc
    30181 atattcacct tgtgcttttg acttaacctc atcataatta tcaggctttc taatagaact
    30241 cttattttcg cttttatttt cttgagattt ttgtggcata tcttccccat ctacaacact
    30301 tatacagtta ggattaacat ctgatacata atattcttct gttataaatt ttgctaaagg
    30361 acctgttttt ccaactggat ttacatttat tgtaggtatt tttttctttg gataaactcc
    30421 acatctagca gttccaccac aatcaataat aactactgct acttcttcat cagaaactcc
    30481 agttttaaat ccatctacaa tttcacaacc cagtagttct tttattttta atgttacttc
    30541 atggatacca ccagcagtca ttgacagtat cttatttcta ttcccttctt tttttatata
    30601 caaaggacct ccccagcctg aagttccctt ttctattttt aatattttat tctcctccat
    30661 tttatctacc tcctaagcct tatttgttgc tctatttttt cttgttagaa aagcatacat
    30721 tttttctgtt actatacctc ttataaaaat tacaattaga ccaactataa aataccacaa
    30781 tgccaatgta gtagtttctt tacctaaagt agtcaaacct gcagatattc ccaaccatac
    30841 aaaaagttct cctgcatttg catgtggaaa aagacctgta attggatgta caaatgaaac
    30901 tgctgcatca taaaatcctg ctttgtgctc ttcttttaaa aatctaccaa atgtatagca
    30961 cataggattt cccaagaaaa atactgatac taatggaagt agaatatatc ttgtaaaaga
    31021 gttctttcct agcttagaag cccaattatt aactctttcc tcaccaatta tcttaatcaa
    31081 agagttaata gctaccatta atacaattag cgttggaaga gtacctgaaa caagacctat
    31141 aaattgttct ccccctttct gaaacaaacc gataaaccac tctgcacctt tacttagacc
    31201 tgtaataacg ttttccataa aattataacc tccctataat atctttaaat ttttaatttt
    31261 actgcttacc ataaatttta caaattacat cttttttctg tactatatgc taatattgta
    31321 aatgtttttt tattaatatc attttaatat aatatttttg ataaataaat acatcttttt
    31381 tcaattttat aaaggaaaaa attgtactaa ttagaatttt cagaaatata caattcttat
    31441 ttcgactata ttctaaattc ttcttagaaa tttaagaact tatttttatt tcttttatta
    31501 ttaaaattat ctaaatctga taaaaataaa aaatagatgc tcttttacga acatctattt
    31561 cttaatcaaa ttatttttta gttttcttat agattatttt ataggtatat aaatatcaat
    31621 ttgtgagttc acattactag gacctaaaaa tcgttcatca tatacttcaa aatcatctct
    31681 tatatcaagt tcttcttttg aacttaaaaa ccaagtaccc catatatatt cataagtttt
    31741 gtctaaatta tctaagctac cagtatgagt aaatatagca tactttcctt ccttaatagt
    31801 ttttgaaaca aatgaatttg gaatcacatc ataactatta acttcaagtc ctattatctc
    31861 attaaattcc atactttcac taactaggtg tatttcagag attgcttcac agattccaaa
    31921 aactctcttt gatggcaaag tatttgggac aatatgatgt acttttctga atttctccca
    31981 caagtcaggt aatgaattat tttctaaaat tactttatcc tttataccta ttacctttat
    32041 tttttctatt tcttttataa ctggtttaat cgttatattt ccaacaagat gtctcataaa
    32101 atctaactct aattttttct ttttaccaac aaatacatca attctatttt ttctatattc
    32161 tatagggcta accttgtata tagatttaaa tgctctgcta aatgcttccg aagattcaaa
    32221 tccactacca atagctatat ctatcacttt tttatcacta tataaaagtt cttttgtact
    32281 acttactaat cgtctttttt ttatataact tcctacactc tcaccaaaca tagacttaaa
    32341 taagcgtgtt aaatgataat aagaatatcc agtttctttt gccacatcat ttacagttat
    32401 attttcatgt aaattattct caatatacat tacagctttt ttaaaatact ttaagtaatc
    32461 caatatggca cctctcttct acttaaactc tttaaatatg taaaatagca ctatttttta
    32521 ctatactaaa atattataac taattcaata cgataaataa aaacttttag ttgatttata
    32581 tatcctaatt atttagaata attaaataca ttttttattc aatgaaatca aaaaagtcag
    32641 atggtgcttt ttcaatattt atgtttatcc tctgtgttat agatttaatg tcatttttta
    32701 aatagtagct ctcccattta ttctctagtc caccccataa aatattaaac tttcctatat
    32761 ttaaatccat aactatactt tttaaagttc caaaaaaatc attatagtaa ttacaagata
    32821 agccatttgg atattttgaa gacaataaat tcattaactc tttctctcca atttttttag
    32881 acttatttat atattcttta attaatttat atctatgaat agaatttttc attgattgtg
    32941 gctctaattt atgaagttta tcaatatgtg tatgattagt agagtgtaaa aaatattctc
    33001 ttttactttc taaactattg attatattta cttctttttt cccatctaaa gtctccacaa
    33061 gtgcaatgtt tccagactta tctgcaagca ataaattaat attgtatgca attggcatat
    33121 cttttaaata ttctaatgct tcatctacat ctttgcaatt ttctaacaaa tatctaataa
    33181 cagcccaaaa ctgtaaacct acaattgctg gttttcttaa accatctgaa ttgcctacag
    33241 gaataccaca tgatgactga cttacaccta agccacattc attcatacct tcacctcttc
    33301 caaattgcat aacggtagta cctatatgtg catattttcc atttacctta gttttacata
    33361 aaacaaaatc ctccatattg tgtgagaaat cgaaattacg tgcaaatagt acatgcccat
    33421 tttcagttaa ttctggtgct aatgcaactt gactacaacc tggtttaaga taagtcatag
    33481 tataatataa aatttgatta caattcactt gaattgcatc agcaaaacct tgcaattctt
    33541 cattaagacc tggacaatat ttatcaaaca actctatcat ctctttttct tcttttttgc
    33601 ttaccagatt agatttatta atctgacctt ctattatctc tggcatatta gcaaccaatt
    33661 ctcctagtct gtatcctatc tcataatttg taccactcaa ttcaatattt cttacttcta
    33721 aagtttccat atgtacccct cctatatatc ttataatcga ttttatcatt cgaattgtaa
    33781 tcattcatga tattttgtgc tacaagttaa aaaaggtcat ataaaaacag ataagcctct
    33841 ttttcattgt taaaataata aaaatatatt taatttcata caaaaaagag tgtctcataa
    33901 actaaaaagt tcattttgag acactcttct tattttaaag agtataatta aaaatagtct
    33961 aagttctact cttccttcat ttttttcaat aactctggat tttcaaataa attaaatcct
    34021 gttaaagcta atatttttat accatcaatt actctatctt ttgcatatga atttatagaa
    34081 gcctccaaaa attcttttgt atgtagttct tctccatttt cagaaaactt catcaaagga
    34141 tgtatacatg gcattatttg acttaaattt cccatatctg ttgaacctaa cattacttgt
    34201 tcatcttcat atattccaaa ttcctccata atctttgtaa atatgtctac caaaacttta
    34261 ttttcattta atccttggca agttggttca aagtgataaa attcaagttc acatccagtg
    34321 gctattgcag cacctctagc acaatttttc actttttcta ctacttcatc aaagtaattt
    34381 tgttcttttg cccttatctc taatcttact tttcccatat caggtattac atttgcagca
    34441 gttcctgctt ctagtataat accatgtatt ctcgttccat ctactaattg ttgtcttagt
    34501 gcatttatat tattatatag taatactact gcatctaaag catttattcc gttatatggc
    34561 ttagctcctg catgagatgc ttttccagta aatatgaaat ctagacctcc tattgctata
    34621 atttcaggtg ttacacaagt ttttgaattt ggatgtatca tcattgctgc atcatagcca
    34681 tcaaatacac catgttctat caagtaaggc tttccatctc cagtttcttc agcaggtgtt
    34741 ccaattatac ttacttctcc cttgtaagta tccagtatac ttgaaagagc tattccagct
    34801 ccaactccca tagatgcaat taaatgatgt ccacatgcat gtccattgcc tggaagagca
    34861 tcatattctg ctataaatgc tattttagga ccatctccat ttttcttggt tgctttaaaa
    34921 gctgtagcca tacctgccaa gttttcctca acatcaaaac cctcttctct taaaaattct
    34981 gatatttttt tagcagattt atattcttgc aaagcaattt ctggttcatc atataaagat
    35041 tgacatagcc ctagaatttt ttctttcttt gaatcagcca cttgtattat tctttctttc
    35101 ataccaatct tacctcccac taaatttatt tagtaatttt tatattttat tataacttta
    35161 atttaactca tgcttatcct cttttaagta tctattttcc caaaactcag catttcttat
    35221 atctaactct atagggttaa aagttctatc actccttttt attcccatct tcttctgtct
    35281 tatataatca taatatgcct ttatagctgg tttttttagt gtaaagatgg caattaaatt
    35341 tatatatgtt aatacaccta tacatatatc acctaatgcc cagcttgtaa gtggttctat
    35401 aaaacaacac attgctgcac atgctataag cataaatcta cagacattaa ttatgtactt
    35461 ttcatgtttt tctgctttaa ttctagttac taagtaagat acattagtct ccatcatata
    35521 tgagaaggct aataaagttg taaatgtaaa taataataaa actattgcta taaaaatatc
    35581 acctaattgt ggatgtaatg tatttattgc actctgtaca tattgtggtc ccggttctac
    35641 acctggcagt gctgtgcaaa cacctgtaac attatacatt cctgttatta caatcataat
    35701 acctgtagcc atacatatta ataatgtgtc tacataaaca gaaaatgctt gaactaatcc
    35761 ttgtttggct ggatgactca cttctgctgc tgccgcacca taagtcccag aaccttctcc
    35821 tgcttcattt gagtatatac ctctttttac tccccaagat attgctgaac ctagcattcc
    35881 tccaaaaact gaaccaaatc caaatgcaga tttaaacatt gttacaatag cctctggaac
    35941 taaactaata tttgttataa ttattactaa tgtcataata aggtatgctc cacccattat
    36001 aggtactact ttttcagcaa ataaaccaat ccttttaatt cctccaaaaa ttattatcgc
    36061 taatgcaata gaagatgcta ctgctattgt catttttgaa aatccaaatg cttgattcat
    36121 tgctagatat aaagtgtttg attgtgtacc aggcataaaa aatgtataac ttattattgc
    36181 aactattgaa aataaaactg aacacttttt ccacccaaga cctttttcaa aataatatgg
    36241 aggtcctcct ctatactgcc catcatgctc atctttatat atttgagcta gagtagattc
    36301 tacaaatgca gttgctgaac ctaatgtagc cattatacac atccatacta atgctcctgg
    36361 acctcccatt gctattgcta cagctacacc agctatattt ccagtcccta ttcttccagc
    36421 catagatgta gcaaaacctt gaaatgatga tataccaaca tgagaactat ctccttcaag
    36481 caagagagta aacatttctt ttacatctct tatttgaaaa aattttaatt tcaatgaaaa
    36541 atataatcct atacacaaac acattgcaac taatacgggt gaccaaacaa ttccattaat
    36601 ggtgttaact aaatcggtca cttaactcac caccattcat tttatattta tagacaataa
    36661 tttaaacagc tatatttcaa tattttatat aatctttata ttaatatatc taaaaaatct
    36721 accttctatt tatttatatt atctttaatc tacaatctac aaatatttat ttctaaaatc
    36781 aagagtatta atcatatcta aacataaatt tataaaattt ttaacgacgt gtgtttgaat
    36841 aataatcaaa caatataaat tggaatacat ataatgaaaa gcctgaaatt attattatat
    36901 aaatagtaca atatatattt attaatatat aattaaatag tatctagtta gattttaaat
    36961 tttcgtattt attatgaggt ttaaaattga gtacaactac catctatttt taaaatctct
    37021 tagaatttaa attaaatagg tttatgtagg taagaaaata gataataatt gccactcaat
    37081 tttacacctt caggggtaac tttatgttaa aacctagaaa acttgataac attttgattt
    37141 ttatacttta ttctctaaac attattataa aacttaatct attgatattt tttatgttat
    37201 ttatacaatc acattcatca aaataagtat tgtatttata tatacttaat taccaaattg
    37261 aatatttaag cttctaattt acttgctctt ctctttttaa cctttaatat atataaacaa
    37321 gatagtattc caataactag aattgctatt tggaatataa atgtatatgt gtaaccttta
    37381 ttgccataag tatctatcca gtgtcctatt aatgcaaatt ggaatacatc tggtgaaaat
    37441 cctaaagctg cagctatacc tatagtagtt gctgaatatt taactggaac ttttacttca
    37501 tcttgtactg cataatatat accttttccc atgtaaccta atatacctac tacaaatgtt
    37561 aaagctatga atatagtcat tggagttgat gcaggtaata ctaggaataa aactattact
    37621 gctataccaa atacatatat tggtaaaagt acttttgtag gagattttaa tttgtctgca
    37681 caatatcctc caaatggtgc tccaaataat tttagaccat gctgtcttat tattgctaat
    37741 gcaccagata atgctacaga acctccaagt acagatgtta tatatggtgt aaaataagac
    37801 attgtaactg tgaatgaata tacacagaat atacttattc ctactagcca agtatttggt
    37861 gattttagta ctgttataaa atcaccagca gacatttttt cacctgcttc ttctctttct
    37921 tctttaatat ctacatcttt aattacaaac cataatactg gacacattgc tattgataat
    37981 attcctaaag atatcattac ccatctcata cccaatgtag gagttgcaaa gcatgtataa
    38041 atatataaga atattgctcc cattactact ccagaaactc caaccatagc ttcattaaat
    38101 ccataaacct taccttgatt atcttttcct ataactctaa gtatttttac catagaagga
    38161 tagttcataa ctaatgatgt gattgcacaa cctacccaag tagcaactgc aaatggatag
    38221 ttcatattaa atgcaaataa aaatgatact actccattaa gaaatacaga acctaaaatt
    38281 atctttctat aatcaaatct atctgctaac cagcctccta taggagctcc aaatatatta
    38341 cctaacccat aaattgtaag tagaaaacct agttgagtgt ttgtacattc taatgctttt
    38401 agaattggat catataatgt atattggata aatggtataa tataaactaa ttcccaagat
    38461 attgctataa taacaagttg aaacattaac tttccaaact ttataccgtt ttctttttct
    38521 cccatattta aaccctcact ttttatattt attcacaagc ataattgagt tcttttttta
    38581 taacttctgc aagtatctca acacctttaa cgatttgttc ttctgacatt gttgtatagt
    38641 taagtctcat agtatttttt ggaccattat ttgcaaagaa ggactctcca gaaacataag
    38701 caactccagc atcaatggct ttatctaata aatcatctac atttatactt tcaggaagtt
    38761 caacccatat aaacattcct ccatctggtt ctgtatattt agcttcctct gggaaatgtt
    38821 tcttcatagc atctaacatt agcagacatc ttttcttata ctctgctctt attttttcta
    38881 tatgttcatt taagttgtat ttctttaaaa attctattac ttgtacttgc gaaaattgat
    38941 ttgactgtaa atctatacct tgttttaaaa gttctgcctt atctatgatg tctacattac
    39001 cacacatcca agcaactcta aatcctggac ataatacctt tgaaaatgac ccaaggtaca
    39061 atactttatc tttagtatca agagatttaa gtgtaggtag aggttctggt gtaaatctta
    39121 tttctccata aggattatcc tctattacta tgacatcata tttattcacg acttccataa
    39181 aatcttttct tctttgtaaa gaccatgttt ttcctgtagg gttttgaaat gttggtatta
    39241 catatatcac ctttatgtta gaattttcag ataataattt gtctaaatca tctgttacca
    39301 ttccttcttc atctgtatct actcctaaaa aatcacattc ataaggtcta aatgcattta
    39361 ttgcacctaa gtaacttgga ttttctgtaa ctactacatc tcccttttct aataaaatca
    39421 tagcacttaa tgctatccct tgttgtgacc cagtagttat tataatattt tctgcttttg
    39481 tatcaatatt ttcttcttct ttcattcttt ttactaatag atctaacaac tcatcttcac
    39541 ctttagtagg tccatatgct agggcaaatt ttcccctttc attaagtact ttttgagtta
    39601 tttcacttat ctcttctatt ggaaataaat ttgggtcagg aagccctgca gcaaaagata
    39661 taacagttcc accacttgct accttctgag ctattttctt ttgagaatct cttatagctg
    39721 aagcttttac catatccatt ctttttgcat atttcataat actttttcct ccttaataat
    39781 aatttcttat tgtgatgcta ggcacgctaa tgctattgaa tttattttta tttcagctgt
    39841 gtcagaacgt gaacctaaaa ttatcggatt tgttgctcct aaaactatac ctgcccactt
    39901 agctttatta aatctaagcc atgactttcc taatatattc cctgcttcta tatttggaaa
    39961 tactaataaa tcaacatcac cagcaatatt acttttaata cctttatgtt ctgctgcatg
    40021 tgcatcaaat gctacatcaa atgctattgg accttccact atacactttg gtatttctcc
    40081 cgatttttcc atctctacaa gtaggttggc atccactgta gattgtatct tagggtctac
    40141 catttcattt gcagtaagta tcgcagtttt aggattttcc atgcctatac ttttcatagt
    40201 aagaagtgca tttgtcatta tatctttttt ttgatttaag tttggcgata catttattcc
    40261 actatcagta caataaagaa gtttatgata ttgaggtaat tcatatactg caagcaaact
    40321 taataatctt cctgttctaa gacccgtttc tttatttaat atagctctca tatagacact
    40381 tgtatttact aatcccttca taagaacttt agcttcctta tttttaacta tctctacagc
    40441 ttttttaact gattcatcgg gattttgaca acctattatt tcatgacctt ttaatccaat
    40501 ttctcttgat atactttcta ttttatcctt gtctcctaca agaattggct ttataatgtt
    40561 taaatctgtt gctgatttca cagcctttaa tacttctttg tcttctgcaa cagcaacact
    40621 tacaataaca ggttcaagct ttttagcctc ttctaataaa ttattaaaat cttttaacat
    40681 actctttctc ctaaatatta ataagttttt gctatttctt ctccattaag tactctaagt
    40741 gcccctagag caagtgcctc catttccatc tctcctggta ctatctctat tggagctaga
    40801 tatgaaactt tttctgctac tcctttgact accatttctg agtgagatat ccctcctgtc
    40861 aagataactc tatctacatt ccctgaaagt gaagctccat acatagaaat ttcttttgct
    40921 acttgataaa taaatgcatc cattataagt tttgcctttt catcaccctc cttgattctg
    40981 ttttcaattt ctatcatatc ctttgttcct aaataatcgt acattccccc aatcgaactt
    41041 acttttgcga ccatttcatc atgagtatat tttccggagt aacacaattc tataagagga
    41101 tatgcaagta atccaccact cctttctgga gaaaatggac catcagacct accaccactt
    41161 ccatcaatca ttttgccttg tttatgtgct acaatcgata ttcctgaacc taaatgagct
    41221 acaataaagt tataatcctc gtattttccc cctagttttt gtgcaatttt tcttgaaaca
    41281 gctttatggt ttaatgcatg taaccaactt gctttttcta tgtctgatat tcctgtaatc
    41341 ctcgatacat catcaaattc atctacagaa actgggtcta ctacaaatga ttgtactcct
    41401 atttcatcag ctatagtttt agctaataat gcacctaaat ttgatgcatg ttccccattt
    41461 atttcatttc tcatatcctc aatcatttct tcactcacag tataggtacc accttttata
    41521 gccttcataa gtccaccacg accaactact gcgtcaaaag aatttatact atgattctca
    41581 ctacttaaaa tatctactat cagttgtttt ctataatcat attcatcaaa tactttagaa
    41641 aaatttttta aatcttctct tgtatgggtt atattttttt tcaaaatttc attttcatct
    41701 tggaaaacag aaatttttgt ggatgtacca ccaggattta ttactaaaac tttcaattta
    41761 acacccccta gttctactat acagaacgtc gttcttgtat tccgacctaa agacttcgtc
    41821 ctattgttca gaacgacgtt ctatatttta ttaattaaat actaacatat aaaaataagt
    41881 atttcaataa ttattttaaa tatttaaaat attcattcgt agtcgtatcc agcttcaaat
    41941 gcttctacat ttttagaatt gaatttacct ttgccttgat tttcaaagta ttcacacata
    42001 ccactttcaa attcttcttt tgtaaataaa tccaaactct ttaccatagc acctaacatg
    42061 caaatgttag cagctttttc attgcctaaa ttttgtgcta tttcagtaac aggtactttt
    42121 ataacattaa tgtcttctct gtactttcta tccttactta ctagtgattc attgacaaac
    42181 atataaccat tttttttcat taaactttca tacttatcta ctgatacgct gttcattccc
    42241 aatagtatat ctggattttt tacacaagga tttgcaattt tttcatcact tacaacaaca
    42301 ttgcaatttg cacttcctcc cctcatctca tttccataag atgggaacca tgtaattttc
    42361 ttttctgcct tatatgcaac atacattata atttttcctg ctgtaagaac tccctgtcct
    42421 ccaaaaccag cacatataat ttcattcaac atattatttc ctccctaatc aataaattct
    42481 ccaagtggat actttggaac aagttcattt tcaattctct tcatagcatc tactggcttt
    42541 aatccccagt ttgttggaca tggtacaagc acttctatta agcaaaaacc tttcttttct
    42601 ttttgttttt ctagagcttt tttgatgtat ctttttgttg tatttatttc tttagggtta
    42661 gttattgttc ctcttgctag atatgctata tctaaatttc ccataacttt tacaacatca
    42721 aatgttgaac catgatctgc gtaatttcta cccgctggag tagaagctgt atattgacct
    42781 tctatagtag ttggagccat ttgccctcct gtcattgcaa acatattatt gttcataaca
    42841 agaaatatta cattatcatt tctagtagca gctgacatag tttctccaag ccctattgca
    42901 taagctccac catctccagc tattgtaaat atatatttat ctggtctaac tcttttcata
    42961 gctgccattg ctgctcccat tttaccatga ggtggaacga caacatctac attcatacta
    43021 aattgaaaca tatgattaca acctatatct gaacatataa ttgtatcttg acatatatcc
    43081 atttctgtta atacttctcc aataattcta tcgactatag agtgtccaca gcctccacag
    43141 aacatatttt cacacatcat tattgctggt gcttttttag ccataattaa aatacctcct
    43201 cttgcttagc ttttccatct ataatctgtt gagcaaaatc tattaattga tttacttctg
    43261 ccatatattg agctgttgct actgaatata ctggaaatct attatcacat gctataatta
    43321 catcttcctt catctgtgcc atcatgttca tttcaactgt tacaagtccc ttcaatgaat
    43381 cacttaattt cttaaatgct tttcttgggt aaggccacaa tgtttttggt cttattagac
    43441 ctaatttcat tccttttgct ctagcatctc taactgcacc ttctgctatt cttgatgaaa
    43501 taccgtatgc cacaaatacc acttcagcat cttctatttc tatctcttcc catctttgtt
    43561 catcttcttg aacttttctc attttttcta tatacccttt ttgccatgta tcttggtctt
    43621 caaaatatgt tatatcagtt attactttat ttttttctcc tacaggtgtt ccttttgcag
    43681 cccatggagc tttatccata tcgtattctt tcattggtgg tgctatacaa ggttctacca
    43741 tttgacctat tgtagcatca gaaagtataa gtactggatg catatatttt tcagccaatt
    43801 caaaagattc atatgccata tccatatttt cttgaacact attaggtgct aacacgatta
    43861 aatgataatc tccatttcca ccgcctttta ctgcttgcca ataattatct tgaccagctc
    43921 ctataaatcc atcacctata ccatatcttt gcacacatgc tacaactgct ggcaaaccag
    43981 ctgataccca atatgcaata ccttcttgtt ttaatgaaaa tcctggacca gatgaagaag
    44041 tcatagctct tgctccaagt gcacttgctc ccataaccat atttacactg gctatttctg
    44101 attcaccttg gataaatact cctccaactt ctttttgtct ccatgccatc atttctaata
    44161 tttctgattg tggcgttatt ggataacctg cataaaatct gcaaccacca cgtatagcac
    44221 cttctgctaa agcttcattt cctttaatta ataaactttg catacctttt ctcccctcta
    44281 ataaaaataa tttataatat ctcaaatact aaatcagggc acattgtata acaagcgcca
    44341 cattgaatac atttttcttc atcgacttta atagttacaa agcctttttt atttgtgtag
    44401 tcagaaagac ttattgcatc ttttttgcaa gcttcaatac aaagatagca tcccttacat
    44461 ctttcaacac tcaacttgac tttttccatt tctcaaatct cccctttatg taatattttt
    44521 acttaatttt aaatatataa tatttatatt ttgtataaat actatatatg catcaatttt
    44581 gttctatagt atagaacctt gttctatttt tattgcttaa ttaaaagata acacattcgc
    44641 ttatatattt caataacatt ttaaatttta agaatattta attttagatt aaagaaaaat
    44701 aggctacatt taaactgata tttacaaata acaatttaaa tatagcctat ttttattatc
    44761 gagattaaaa atcatctaaa aagttcagat atactttttg cagtttctat aactctttta
    44821 atcttatact caaagtcccc ttctctcatt cttatagttg gacctgacaa acttatggct
    44881 gcaatagctt tattattttt atctaagata ggtgctccaa tacaagttag tccatgttct
    44941 agttcttcat catctatagc atatccttgt tcttttattt ttgctaaaaa aagcatcata
    45001 tcatcccaat tatcaattgt atgttctgta tacttgtgta ttggtgtttt tctatatttt
    45061 tcaaaatcta tagaatcatt aaatgccata agacatttac caactgctga acaataacat
    45121 tcactacttg aaccaacgga tggatttact gaaagtaatt gatttgaacc atactcttta
    45181 tgtattatga tacttcttgg agaatcttga gctctttctt ctaatataga tacattaact
    45241 acttcgttaa attcttgatt taattttttc gtatatggtt ttactatttc agtcaatgac
    45301 attttttctc ccacaaccat acctattgca tataaattta ttcctagcca atacttacca
    45361 ttctctgcat tttgtataac aaaacctttg ttttcaagag taaccaaagt tctatgtaca
    45421 gtacttttat atactcccat agccttactt atttcagtta ttcccatttc tctcttttca
    45481 tgatataaca gcaaaattat gtctagggct ctatctaatg catttattat ttctcccata
    45541 tacaaaaact cctcctgcaa atattaagtg ctactcccac actctactaa atattatata
    45601 ttaaaattac aaaattatct atttatctta attatatttt ataaaacaaa aatattatac
    45661 ttaatttgta aaataaaaac aaaatactca ctatgtcctt attattctta cttttaatag
    45721 aattattctg ttatattttt atcctgacta gataataata tatatatcta ttatacaata
    45781 gatatatttt tatacaagac taacaatgag gtgaaataat ggataatttt aaaaagatat
    45841 tgttaaatga actacctaat tttaaagaat attcttcaaa atttttaaat ggagaaataa
    45901 ataaaatgca atataaggga ttttctggtg gatatggtgt ttatgctcaa agagacaaaa
    45961 aatcttttat gataagactt agagtatctg ctggagtttt atctcagtat caacttaata
    46021 aaatctatga aatagctatt aaacacaact tagataagat acacttaaca actagacaag
    46081 ctatacaatt acacgattta tctataaatt caattgttga tatcatggaa gaaggaataa
    46141 aaaatgatat attcactaga ggtggtggtg gtaattatcc tagaaatgtc ggattatctc
    46201 cattatctgg agttgaccct agtgaagtct ttgatgttac tccatatgca gttgctactg
    46261 ataaatattt tatcaaaaat gctactacat accatttacc tagaaaatta aaagtttctt
    46321 attctaattg ttacacagat actgctcatt gtagtataca agacttagga tttgttgcta
    46381 ctttgaaaaa tgatgaacca tatttcagag ttttcttagg tggaggtcta ggtaaacaac
    46441 ccaaagttgc tttagaactt gatgaactta taaagccgaa agacgcctta tattgtgttg
    46501 aaggtatgat taaattcttt atggattatg gaaattatga aaataaaaac agagctaggg
    46561 ttagatatat ggtcgaatca cttggtgaag aactattctt agaaaaattt aaagaatact
    46621 ataaattaga aaaagaaaat ggtagtcttg aactcaatat tgaagaaata gattactcta
    46681 aacctggagt taaaatagat atacaagatt ctagactaat acctcaaaaa caggatggtt
    46741 tatacactgt atatatacat ccagttggag gtattttgtt aacaaaggat ttaagtactt
    46801 tacttaaaga attagataat gttgaaaatc ctatgattag actaggaatg acagagggat
    46861 tatatatttt aaatttaaat ggaaatgaag caaaaagaat attagaaata agtaaaacta
    46921 ttagttgtaa ttctcaatta gaacaaagta tatcttgcat aggtgttcca atttgtcaaa
    46981 tgggcataca aaatagtcag aaaatgttac atgaaatcat agattatttt agattacaaa
    47041 ataatgaaga aattttaaat aaagcaccta agttatatat atcaggatgt ttaaattcat
    47101 gtggtgttca tcaagttggt agcataggtt tatgtggtaa aaagaagaat gttgatggta
    47161 tatctacaga tgcatttgaa ttatttgttg gaggcagttt tgaaataggt aagactagat
    47221 tgggaaaatc acttggagat tttaaagcta gtgatattcc tgaaatgctt tataaaatat
    47281 cggacgcatc ttcaggcaat ttttatgaat gggtaaattc aaatgataat attttaaaca
    47341 aaataactga taagtataaa atataattta ttatatttac ttacaaaaaa catgggtgtc
    47401 tcaaaatgaa ctttttagtt tatgagacac tctttttcta tgaaatcaaa tatattttca
    47461 tcatctcaac aatgaaaaat aagactatct ctattttgag acagccttat ttcttataaa
    47521 tagtttaaat tttatttata aacaatttta gataaatcac aaattcctag catagtatca
    47581 tatacttgtt taagtaaagc aagtctattg ttcttaatag cttcatcatt atccatgacc
    47641 ataactgtat caaataaatt atcaactact ggtcttaaag atgcaaattc atctaaagca
    47701 ataccatatt tcttatcctt taataattca ttaactttta cctttacttg tttaaattca
    47761 ttgtaaagtt taatttcagc atcttctttt aataaagatt catcaatttt atcactttct
    47821 gctttttgag ctagagtaga aactctatta aatgcagtaa gcatctccac taattcatct
    47881 ttttctagcc aattattaag ctctaaagct ctcatatgca tatcagaaac atcatttata
    47941 tcagaactta aaacagcatc aacaacatca tatcttattc ctaaatcttt aaatagattt
    48001 tttactctct cattgaagaa attcattatt tgctcaacaa cttcttcttt attaaaatct
    48061 aattcagaat aattgtctaa agcatgttca ataagtattt ttatatccac agcaactttt
    48121 ctgtccataa gtatactaag tatacctaaa gcttgtcttc ttaaagcata tgggtcttga
    48181 gaacctgttg gttgtattcc tatagcaaag aaacctgcta ttgaatccaa cttatcagct
    48241 attgataagg caacccctgc attagtctta ggaagtatat ctcctgcaaa tcttggaaga
    48301 taatgttcaa aaatagcttc acttacaaca tcattttctc ctccaacttt tgcgtattct
    48361 tttcccataa aaccttgtaa ttcatcaaat tctcctacca ttccagtaac taaatctgcc
    48421 ttagataatt tagcagccct tatagtatct gccttttcat ctactaaacc taaactatca
    48481 agtatatcag cacttaattt ttcaagtctt aaagttttgt cgtaaatagt tcctaatttt
    48541 acttggaata caacagtttt taatttttct atgtagcttt ctaagtttct cttagtatct
    48601 tctctataga aaaataaagc atctgcaagt cttgcttcta aaactttttc atttccagct
    48661 ttaacattgt ctattctgta agaatcacca tttctaacag ctataaagtt aggtaacagt
    48721 tttccttctt taagtactgg aaaatatctt tgatgttgtt tcataggagt tataacaact
    48781 tcttttggta gttttatata atccacatca aattctccat aaaaagcagt tggatattca
    48841 actaaataag ttacctcttc aagtaaatct tcatcaaatt caacttctcc acctaaagaa
    48901 tttgctactt ctatacattg ttttcttatc atttcttttc tcttgttttg gtctaaaact
    48961 atataatttt tttctaattt ttcaaaataa tcttctatag aatcaacttc tattgtactt
    49021 tcacctaaaa atctatgacc ttttgttaca ttagaagata ttattccttc taaatcaaac
    49081 tctaatactt tatcatttaa caatgcaact atccatctta taggtcttgc aaatttaaga
    49141 ttttttcctc cccaacgcat agcttttggg aatactacag attttatagt ctctggtaat
    49201 atgtctttta gtacttctga agtttctttt ccatcttgct ttatagtcgc aaatatatat
    49261 tcttcttttc caacttgttt aaaatatatg tcagattcgc ttaatccttt gctttttata
    49321 aatcctaatg ctggttttgt taaattattt tctgcatcaa cagcaatttt tttagcagga
    49381 ccctttattt cctcttctaa atcactttgt ctatcactca atccttcgac tactaaagta
    49441 agtcttcttg gtgtcccata agcatttatt ttatcaaaag ctattctatt ttcatcaaat
    49501 aatttactaa gattgttttt taattgttct agtgtactgc ctacaaatct tgatggcatt
    49561 tcttcaacac cgatttcaaa taaaagataa tttttcatta tttgtcaccg tcctttaaaa
    49621 gagggaatcc catttcttct ctttgtttta caaaagtttc tgcaacagtc tttgccatat
    49681 ttctaactct acctataaat gaagctcttt gactaactcc tattgcacct cttgcatcca
    49741 atgtattaaa tgcatgagag cattttaaca catagtcata tgacggtatt acaaggccat
    49801 tttccataag tcttaatgct tctttttcat atatatcaaa cagattaaac aacatatctg
    49861 catcacataa ttcaaatgcg tacattgagt tttcatactc agctttatta aatacttcac
    49921 cataagttat tttatcattc cattttaaat cataaacact atcaacttct tgaatgtaca
    49981 tagctaatct ttctaatcca tatgtaattt ctcctgtctc aagctcacat tcaatattac
    50041 ctacttgttg aaaatacgta aattgagtta tttccatacc atctagccaa acttcccatc
    50101 caagtcccca agcaccaact gtagcagctt cccagttatc ttcaacaaat cttatgtcat
    50161 gctcacttgg gtcaattcca atctctttca aactttccaa atataattct tgtatattat
    50221 ctggagaagg ttttagtata acttggaatt gatgatgttg atatagtctg tttgggtttt
    50281 caccatatct tccatctgct ggtcttcttg aaggctctac atagcatact tgccaaggct
    50341 caggtcctaa tgatcttaaa aaagtattag gattcatagt tcccgcacct ttttcaatat
    50401 cataaggttg catcatgata caaccttgct ttgaccagta tttttgcaac gccagtatca
    50461 tctcttgaaa attcataaaa atccctccta taacaataaa gcctctcgtc tacacgaaag
    50521 gctattttaa tagttcttct acaactttta gaatatcaaa ttctataaaa tttgtcaatg
    50581 ttagtgataa ttcttataat tatcttctct tcatttttta aaagtcactt tatatctatt
    50641 tattttcgtc ttcgtcttct ttattctttt cagattcttc tttcataagg tcagcagtta
    50701 catctttgtc atcttctttt ttgtcaacta ctacatcctt cacatctttt gctgcattag
    50761 ttatcatatt cttcaaaacg tgaagttttt cttcattcaa ttcacctaaa tctacaattt
    50821 ctccatcttc ttcattttga acttttatac gatatttact tataacagca gctgataatc
    50881 caactaaagt agctaatggt acaaaagcta atccaacaac tccaactgtt aaaggaatat
    50941 tcatcatagt ttttccatct ttttcaacta ttattctcac tacactactt tttctaagaa
    51001 gctcttttaa ttgaaacttt atattttctc catctttgcc aaatacttct tccatagttt
    51061 ctttagcaga ttttgcttta caattacaag tatttttttt attttctaaa tatattactg
    51121 cctcaattac atctccattg cacattacta atgcttcttt tgcttctgca taagttgctc
    51181 ctggaactct ttcaaagact gaatcaacca tttcaatagt tatattacta ctcatcatta
    51241 tccactccct tattattttt tacactttgc aatacgtgta atgatttaaa attaatatta
    51301 tcaacataaa ctttcaaata cttgtctaga atattctcaa gttcatgtgt tatatatttt
    51361 gatactttag ctttactaca tgttaaaata tcatttctta atacatattc cataagactt
    51421 atagttgtta agtctaattt tatattatta tcaaaaagtt tactacactt actacatagt
    51481 ataccacctt cgtagatatt aaacacagaa ttttgtaaaa ttttacattc acaattaatg
    51541 catttattta ctataggttt aaatcctata tagtctaaaa attttaactc gaatgctgct
    51601 gttataaacc tattgtctgt attatcctgt gtatacaaat acagagtctg cgcaagtaat
    51661 ataaatagcc tattattagt ctgattttca agtatagaat tttcaactaa ttttgtaata
    51721 tatgtagcat aagaaaatgc ctctatatca taggatatat tataaaaact ttttattatt
    51781 tcactttgag taaccttgta catattacct tgttttttta aggtaaaatt gctataagaa
    51841 aataactgtg atgatgaaag caaagagctc ttattttttt tagctccttt tgctattgca
    51901 gatacttttc caagctttct tgtaaatagt gtaagtatta tatcactttc cttatacctt
    51961 atagctttaa gtactatccc ctgggtgttc aggattatca tcgtcttctt ttttctccct
    52021 tacttcttca atttcttcat gtatgttttt gcaatcacag aaatataaat atgcatctat
    52081 actacctgtt tttttaaaaa cttcccaact gatattgttc atttttaaaa aacccccttc
    52141 ttacatttat acttatattt ttagtaagaa gaggataaat catacataaa gttattaaac
    52201 aatttttgac aataatgccg ttgttattat aaagtaaact gctataccag ttatatcaag
    52261 agctgtagat ataattggtg atgaaactgt agatgggtct gcatccattt tttttaataa
    52321 aacaggcata aacgcaccta ttgttgcacc taaaaccata tttataaata atgatattga
    52381 aacaattaat acaatgtcta actttctcat aacaaagtaa attacaatac ctgttattat
    52441 actacacaaa agacctgtaa taatacctac aataccttct ctaaccacat tgctaaaatt
    52501 taaatcctta ttagataatg ttattactgt aacagatgat gattgagttc caatatttcc
    52561 acccatacca attactacag gtataaaaaa tactaatgga gcatatacag gattcattat
    52621 atagtctaag ttagaaagta ttaacgaagc caacaaccct ccaactaagg taataattaa
    52681 ccaaggtaat cgtcctctaa gtgctgatat tatttgctct ctcaatgtag ggttttcttt
    52741 ttcagcaact tctctttcat gttctgaact tcctgcaaat ttatacatat cttcagttgc
    52801 ttcttcttcc attacatcaa ttatatcatc tactgttatt attcctttta atttttcttg
    52861 tctgtctact actggaattg ctattaaatt gtatttagat actaatctta ctgcttcttc
    52921 tctatcttca tctacataaa cagagattat attttcactc atcaaatctt ctactatatt
    52981 tgcgtctcta gctattatta attctcttaa tgacaatact ccaactagtt tttcttcatc
    53041 atcaaccaca tatatataat aaatagtttc agcttcttca gcttcttctc tcatatggtc
    53101 tatagcctca agagctgtca tatctttatt tatagaaata tatccagtgg tcattgttcc
    53161 accagcagaa tcttcatcat agaatagtaa ctcttttaca taatcggcat tctcttgatt
    53221 caaaagattt attatgtgtt ctctttcttc ttcttcaagt tcactcaact tgtctgccat
    53281 atctccaaga gacataagtt caagtatatt tttcgagtgt tctacatcca gtttagataa
    53341 aatactaata aaaaactcta cactaccttc ttctaatata gaagatgcca tatctaaagg
    53401 aagtacttca aataattgaa ttttcatgtc ttcctctaaa ttttccatta tatcgaatat
    53461 atcaattata tgatattcct ctattaattc tcttaactcc aatactttat tattatcaat
    53521 taatgatttt acttcatata ataaatcttg ggaagcatcc agtttcctat ccatataacc
    53581 cacctttatt tatcattata tccaaaatta tttatataat tttgtaaatt tctccaattt
    53641 tctttgactt taacccataa ttgaagattt atttgtgaac ctaaaagcaa ttctatatct
    53701 tgtcttgctg acttacctat tccttttagt ttcctaccat tttttcctat tattattccc
    53761 ttatgtgaat ctctttcaca gtatattaca gcagatacat ctactatttc cttatcattt
    53821 ctcgctttca ttttttcaat ttcaacagct acaccatgag gtatttcatc attaagatag
    53881 tgaagaactt tttctcttat aagttctgct attaatactc tttctggctg gtctgtaatc
    53941 atataatctg gaaaatactt tggcccttct tctaaataat tttgtataac ttttattaag
    54001 gtatccgtat tctttccttt taatgctgat attggtacta tttctttaaa aatgccttct
    54061 ctatcataca ttttgattat atcaaatagc tcatcttttt ggtctagttg gtctattttg
    54121 tttacaacta aaattattgg tgtcttaaca cttcttaaat cctctattat ctttctatct
    54181 ccaggaccta tttttttaga atcatcaact acaaataata ttaaatctac atttttaaaa
    54241 gcttctgttg ctgcctttac cataaattca cctaatttat tttttggttt gtgaatacct
    54301 ggtgtatcta agaatactat ctgcatttct tcatctgtat atactgcttg tattgtattt
    54361 cttgtagttt gaggcttatc actcattata gctatttttt ctccaactac attattcatt
    54421 aaagtagatt ttcctacatt tggtctaccc actatactga caaaacctga tttgaacatt
    54481 aactgtctcc taacttttta tcttcttgtt ttaattactt aaatttattt atacttttaa
    54541 atttatttta aatcatttcc agagaaatag tttggcaaca aatcctttat actatgctca
    54601 aacacctctc ctttagtata tcccgttatt atttttatat cagaaccaaa ctctataatt
    54661 acctgcctgc atattccaca tggatatgtt tgctcattat tttctgagtt atcacttgct
    54721 atagctattt tatagatatc cttatcaccc tctgatattg ctttaaaaat agctgttctt
    54781 tctgcacaat ttgttccacc taatgatgca cattctatat tacatccagt ataaacttta
    54841 ccactcttag ttaaaagagc tgcacctact ctaaaacctg agtaaggagc ataagaatgt
    54901 tgtctggcat cttctgccaa ccttaacaat tctatgttat ccacaacaac tcctcctgta
    54961 tacaataatt aaaagttatt tttatttaat actctacatt atatcataaa aatttaatta
    55021 gcacagattt gttttatttt aaatatttta tgtacattta ttttaattat agaacattcc
    55081 aagctgaaat actaatatag ctatcaacac acctaacaaa gctccagcaa tagtctccca
    55141 aaaggtatgt atttttcctt caattctact ttgggcaact aatacagcca ttatatatgc
    55201 aagagtagag gcaacaactc tttcagtcat aagtgtaatt gcagttgcta tagcaaatgc
    55261 taaggcagca tgaccacttg gcattcctcc ttttagagga gtacctgtag aagtcaatgc
    55321 ttttacaact acaacagcta taagaaccaa taatatacat atcaaggtta tatgtaattc
    55381 tgattctctt attttataaa ttaatattcc agatatatct gtcaatttat cataaaacaa
    55441 aatatatcca actactactg aatttagtgc tgccactaga acgcctccag ctgcaacatc
    55501 ttttgctatc ttagcaagaa catgatattc atcagttact aaatcaacag ctttttctat
    55561 agctgtatta aacatttcag caactacaac taagcatatg gacataagta acattatcat
    55621 ttctaatttt gaaaagttaa aaaacaaact tattataaga acagcaactg aacctaaata
    55681 atgtattttc atatttcttt caaatttaaa tgtatacaat atcccttcta tagctgcatt
    55741 aaatgcttta attatacctt gacgagtttt ttctggtttc ataaaaacta ctcccttgtt
    55801 atgtttaact tatttaatat gtgttcttct ttttctctca tttcttttgt attttcatct
    55861 gtatcgtggt cataacctaa aagatgaaac atactatgac atattaaaaa acatacttct
    55921 ctttcaaagc tatggttata ctctatactc tgttctaagg ctctttcaag agatactact
    55981 atgtcaccta gggattcttc ttctaactca acatcctcaa aatcatcact taaaagagga
    56041 aatgataaaa catcagtcac tctatcaact cctctatatt ctctatttaa ttcatgaatc
    56101 tctttattat ctacaaaaga aagactcact tcataattat catcatatcc ttcataatct
    56161 aaacattcta tgattatatc ctttatcttt tcaattaact cctcacttac ttctaattta
    56221 tcttgtctat catctagtat caaatccatt cactacacct actttttatt cattaataat
    56281 gctatatatc tatattacta cacttttact ttcttttgaa agtcttttcc tgcattttcg
    56341 cttttttacg ttcttctttt ttaaattctt ctcttttgtc gtgcttctca taagctctta
    56401 ttattctttg taccaactca tgtcttacaa catctctatc tgttagcatt atagacccaa
    56461 tacctggaac acctttaaga atctctgtag cttgtattag accactcttc ttattttgtg
    56521 gtaaatctgt ttgagttaca tctcctgtaa ctacagcttt agagccaaat ccaagtctag
    56581 ttaaaaacat tttcatttgt tcagaagtag tattttgagc ttcatccaat attataaatg
    56641 aattatcaag tgttctacct ctcataaatg caagtggtgc aacctcaata gtacctcttt
    56701 ctaaatactt attaaattta tcagcaccca acatttcaaa taaggcatca tatagtggtc
    56761 ttaaatatgg gtcaactttg tcctttaaat ctcctggtaa aaaacctaga ctctctcctg
    56821 cttccacagc tggtcttgta agtataattc tactaacttc atctctttta aaagctttta
    56881 ctgccatagc aaccgcaaga taagtctttc ctgttccagc aggtccaaca ccaaaagtta
    56941 tatcattatt ttctataagt tttatatatt ctttttgacc taaagtttta ggttgaacag
    57001 cttttcccct ttgagttatg acgattgtcc cctcaagttc ttttattttt tgttcacttc
    57061 cttcaagcaa aagagataat gaataagaaa tactctgctt atctaaatgc ttaccatttg
    57121 atacagtttg gtgtaattca ttcataagtt ttaatgcaga atctacattt ttttcttctc
    57181 caattaaaat tatattgcct tctctaagta ttacatctat atttaaagtc ttctctatta
    57241 attttacatt ttcatcaaag ttgccaaata actctctttc aaagttacca tctgctattg
    57301 taaatttctt ttgtattatc aattgaatta gtcctcctaa gattttaagt ttaattttat
    57361 tagttgttat tgctattatt attttgacta ttattactat tttgattact attattttca
    57421 tcagaattgt tttgatcttt attatcctta ttatcctcat caaactcatt tcttatatca
    57481 tttaatggtc ttttttctgg attggaagga acttcctctt caccttcatc tggtttactt
    57541 tcttccttta taaacctttc tgcttctgac ttactaagag gataaatttt agcaatattt
    57601 tcactagttt gaactgttat taaatattct aacatatttt tattaacctt aaagttatgt
    57661 tttacatcta ttattctagc cgaagctggg attatgtatt ctaactcttt taaagctttt
    57721 tcagataatt ctttttttaa ctcttcttta ttccttttta cttcaacctt ttttgtttca
    57781 taaaaagtac tcgtttttat ctttattgga aaagtatagt ttcctattga tagttttttt
    57841 tctttatttt caacaacata atctttatat tttatatttt ttctcattgt aaactcttta
    57901 tcataaaaac ttagtgtata tatatttttc ttttctccag tttttttatt tacagtatct
    57961 acataacttg ccttttttgt ggactcataa aaagtacttg cccatacttc tggtattgac
    58021 ttggtattag ctccatttaa taagacatct cccttttgga ctatgtctcc agatttaata
    58081 actgatttac cacttctagg gattaccttt tctattatac cattttttaa agcaattaca
    58141 ttacaataat ttgattggtc tgtagatttt agggattctg ccttttttgt aacagtaaca
    58201 aatatatttg ttccttttac attgatagat aaatatgcca catcattaaa ttttgacatc
    58261 atatggtctc taacttcttt tctatcaata ctcttcttat agactcctgg tcttactcca
    58321 accttataaa gctcatttct aagagcttct ttttttatac cttcaggaga ttgtatatat
    58381 acatctgtca caaactgtga tgtagacatc aataaaaata aagaaacaag agcacaaatc
    58441 cacatacctt tgtgcttata aactcttttg ataataaaag ggaccccagt tttttgcttt
    58501 acctttatat caaacttact tcctctataa acattcttaa attcttttat atcttgtcta
    58561 tctatatgaa actccatttt agtatttttt attctagtta cattgtaaac acttatccca
    58621 tttcttataa gatgatttaa aaattgttcg agtcctactc cttccacaac tataacatag
    58681 tatcccctta taaaacttat caagtgtatc tcctcctaat caacatactc aacattgtag
    58741 ataatccctt ttatacctat ctcactatca gtaatatact taagtgaaag tttatcccca
    58801 gatattttaa ttgttttaac tttagtcttt attcttatta aatcaacttc atattctaat
    58861 attgatagat aattttctat actaataaac gtattacttg taacagtaat aactggttga
    58921 tttacttgta aatcagtgga tatttctaac ataagcatta cccccttaat taattttatg
    58981 cttgaaatag gtatttatgc actttattga tgttgtaaca gattagtttt aaaattttta
    59041 tataataaat acctaatatc taatatatta tttaaacaag aaaaaggtaa tcatattgat
    59101 aaaaaatcaa catgattacc tttttatttt ttcttatata aaatctaaac gtatacaatt
    59161 tttattaatc ttgttctatt aaaccatatc caccagcttt acgcttatac actatgttta
    59221 tttcaaaatt atcttggttt ctaaacatat agaaattgtg tcctactagt tccatttgaa
    59281 gtatcgcctc ctcagaactc ataggtttta cattaaattt ctttcttctt tctattacta
    59341 tattctcatc ttcttcatca tcataatcat aatcatcaaa ttcactgcta ttatctataa
    59401 agtcaagatt ttcaaatctt atgctcttat tattttgaac tttgtcttta actttagttt
    59461 tatatttgac aacttgtcta cttaatttgt cacaaacaat atcaattgct gcatataagt
    59521 catcttctac gtcttctgct cttattattt gaccgttaat aggaattatt gtaacctcca
    59581 ctttttgtct atcctttttc gcacttactg ttactttcac ttctgattca ggatcaaggt
    59641 atttttctaa cctacttaat tttccatcta cgtatccttt tattccgtca gttaatttca
    59701 tttgtctccc agatactatt atttgcataa aaacctctcc cttcaagcct ttccaattct
    59761 aatactttaa tatgttaatc tttaaataca atttttataa atttattgta tttaaattaa
    59821 tattattgta tatgaaaatg attattttta atagtctatt tatttttcgt ttgttatgat
    59881 attattaaaa gtacagggta atttacaaaa tctttacatt ctatttatta ataaaccata
    59941 taaaatagtt caaaaatcct gcataaacaa gccacattaa ataaatcaaa tttatgtatc
    60001 cagatctctt atctatttta gaaaacttcg aaatcattat tatagaaacc aaaatcatta
    60061 ttattatatc tatcaaagct gtaaatctaa gtccaaatcc aaaaaatagt atactccaaa
    60121 taaagtttaa tacaagttgt aatccataat aaaaaattgc atctcttact ttaggtaagt
    60181 tgtaaccctt tcttaatatt aggtatgaag atatacccat caatatgtac aatatagtcc
    60241 aaactatagg aaagataaaa gctggtggtg caaagcttgg ctttgtgagt tgtaaataat
    60301 aggttgaaat atctgttcca ctgataatca ttgttaagat gctacttaag taacctatta
    60361 ttagtggtat aaatatgttt atcaaaaaat tcctaatctc ttttactgat ataatcaaat
    60421 ttttcccctt ctttcaaaat tttctttgat tatagatatg ctcaaatatg actcgttatt
    60481 cccaaaaact ataaaaagcc tagagatttc tctctaggct atatcaatct attgtaagtt
    60541 ttgttttacc aacttattta taagttttcc gtcagctctt cctttaactt ttggttggat
    60601 aactgacatt atttttccca tatccttcat agaagttgcc cctacttcag atatagtaga
    60661 ttttacaatt tcttctaact cttcttcgct taattgttga ggtaggtact cttttaaaac
    60721 ttcaatttca ccttctgttt cttttattaa gtcttctctt ccagcttttt caaattcaac
    60781 taatgcatct ctacgttgct ttaattgttt tgctattaca tcgataattc catcttcatc
    60841 aagctcgacc ctattatcaa cctcatactg ctttatagaa gctcttatta aagttactac
    60901 agattttctc actgtatctt tgtttttcat cgaagatttc aaatcctctt gtaacttttg
    60961 cttaagggac atccccttca cctctttatt cttatttact actatttctt agcgtttttt
    61021 cttcttgctg cttcagcttt tttcttacgc ttaacgcttg gcttatcata gtgctctctt
    61081 tttctcactt ctgacatgat gccagacatt gcacattgac gcttgaatct tcttaaagcg
    61141 ctgtctaatg tttcattctc tctaactctt acttctgaca tttctttttc cctccctcca
    61201 atagcgcaat tatgctggga ctgtaactat gttctttttg cataatatgc attacaacct
    61261 aacactttgt ttattataaa ctaaattttt acttttatca agtattttta tcaagaagga
    61321 actcaatttt tcaataattt agtttagttt tgtcccgctt cgtaattagg aagcttttta
    61381 ccagctaaaa tatgatagtg caaatgttta acttcttgcc ctccatcact tccacaatta
    61441 tttatgactc tgaatccagt ttggtcaaaa cctttctctt tagctatttt attaataaca
    61501 acatgaatat gtgacacaat gtccatctct ttatcaggaa tatcaattaa actatcataa
    61561 tgttttttag gtacaactaa tatatgatat ggagcaactg ggttcaagtc attaaaagct
    61621 aagactctat catcttcata aactttagtt gaaggtattt ctccgttcgc tattttacaa
    61681 aaaatacaat ccattctttc cacctcctat cttataaata ttataatttc tacatgttat
    61741 agcaaaattc cttctacata ttcatctttt acatcattta ttttcacttt taatatctga
    61801 ccttgtatat ttttgtcact ttcaacaaca actcttatat aatttgaagt taatccctca
    61861 tatttattgc cttctatatt ttgttcaaat aaaacatcca actcacggcc gataaattta
    61921 gttgcaaatt tattaaaatt tactttactt aaatttaaaa gttgttcact tctaaagtgt
    61981 ttcatttgag ggtcaacttg attttccata gttgcagctg gagttccttt tcttggtgaa
    62041 tatttaaaaa tatgcatttg tgaaagctct atttctttta aaaactcgta cgttttttta
    62101 aactcttcat ttgtctctcc aggaaaacct actattacat ctgtagttat tgccacatct
    62161 ggcattttac ttctcaatct atctacaata gttttgtact ctaaagttgt gtatcgtcta
    62221 ttcattcttt ttagagtttc atcacatcca ctttgaagtg ataaatggta atgaggacaa
    62281 actttatcca tctttaaaac ttcatttaca aattcatctg taaataaaat tggttcaaca
    62341 gaactaagcc taattctttc tattttttct atctggttta tttgttttat tacatcaaga
    62401 agtttaatat ccctatcctt taaatctttt ccataagagg caacatgtat tcctgttaat
    62461 acaacctctt tatagccatt attagccaat tttttcactt catcgactat actatcaata
    62521 tctctacttc taacgcgtcc tcgggcataa ggaatgatac aataagtaca aaatctgtca
    62581 catccatctt gtattttcat aaatgctcta gtctttccat tagtttggct gatttctatt
    62641 tcttcaaaag ctttaacttt cattatgtca tcaactgtac taactttctt acttgaattt
    62701 atctttttaa tttcttcaac aatctttctt ctatcatttg tgcccatgac taaatttact
    62761 tcttctatat ccaaaatttc ttctggagat acctgagaat aacatcctac aacggctatt
    62821 attgcatctg gattcttctt tttaactcgt cttatatatt gacgagattt tctatcactc
    62881 atatgagtaa ctgtacatgt atttataaca taaacatcag catactcttc actattgact
    62941 tgttcataac catctttctc aaatagttct agcatagctt ctgtttcata ttgattaact
    63001 ttacacccaa gtgtataaaa agctactttt ttcaatttat ttttctcctc ctaaatcact
    63061 tagttcatac aaagctattg ttgatgctac aacagaagct gtctcagttc ttaatattct
    63121 aggccccaat gatacaacat tacaattatt tttttgtatt tgttctattt cttcttcaga
    63181 aaatccacct tctggaccta taaaaattcc aacactatct atattagaat cacatttttt
    63241 tagtgcatgt tttattgaaa ctgttctttc attttcataa gggcaaatat ttacattatt
    63301 ttttttcata tcttctaaag cttctttaaa acttaaaaca cctcttaatt ttggtatctt
    63361 acctcttttg ctttgctttg ctgcttcata aattattctt tcccaacgtt caaatttttt
    63421 atcttctttt ttgtcatcaa ctttaacaac acttctctta gtttgaacta atattatttc
    63481 ttctacaccc acttcagtta atttttgaag tatcatttcc atttttggag cttttggaag
    63541 tccctggtat agccttactt taagttctga ttctctattt atatcaactt tttctaaaat
    63601 ttctaaatta actatactct tatctatatt cattatctca caaatatact cattattatt
    63661 cttgtcacat atttcaagtt tctcacctaa tttgcatctt aaaacttttg aaatatgttt
    63721 tacatcttca ccttctatag tgcaagtttt atcttgtaga tttatattat ttttttcaac
    63781 aaaaaatcta tccattatac gtcaccatat cccttatttt ttaagcttag aaactattgc
    63841 tgaccattca cctaattttt gaacttcaac tatttcaaat ccattttcaa ttaagctttc
    63901 tttaacttct tctactttat ccaaaattat acctgaagat atgaatatag catcttcttt
    63961 cataaagttt tgaacatctt ttgcaagtat ctttattata tcagctatta tatttgcaac
    64021 tattacatcc gctttatctt ttattacatc agttaaatta ccatgcatta cagatacact
    64081 tttttcaact ttattttcaa gaacattttc ttttgcaact tttacagcca cttcatctaa
    64141 atctacagct acaacttctt ttgctcctaa tttagctgct gctattgcaa ggattccact
    64201 accacagcca atatcaaata ctttagaatc tttattcacg tacttttcta attctctaat
    64261 gcacatacta gtagtctcat gtgtacctgt accaaatgcc attccagggt caagctctat
    64321 gattaaatcc ccctcttgca tagcataatc ttcccatgta ggctttacta ctaccctttg
    64381 tcctactttt gttggtttgt agtatgcttt ccatgcattt gcccaatcag cttcatttac
    64441 ttggtccaat gatacacttc cttcacctat atctatacca aaatctttta accctaaaac
    64501 tttttgcttt attatttcga caaattccat cacatttttt tcttcagaaa cataagtttt
    64561 tataagaaca tcatcttctt cattcttttt aaatacttct tcttcaacat aatcccagtc
    64621 tagttcattt ttcttttgga ataaaaagtc ttttgggtct tctattacag ctcctccagc
    64681 tccttgttca tatagtatat tcgttatagg ttcaactgct tctgttgttg tttttatagt
    64741 tacttctatc caattattca taagtttacc tctcttctct atagtaatat tcctgttttt
    64801 ccataacttt tattatatca taaatataat attttgttgt tttatattat tggttttaaa
    64861 ttcaagctaa taatatcctt atataatagt cagaatattt aaaaatccga ttagttaatt
    64921 ttaaacctaa taataaaact tctattatat ctactatatc aatatttgaa atccacttag
    64981 ttaatcttaa acatacaaaa tctccaactt ataattattt tcgcgatgta cctgaaaccc
    65041 acttagttaa tcttaaacct caaatttatt atctatatac acttgtaaac actctatctc
    65101 acaacttatt tttcctttta aaaaaatagt ttttacagtg agcttacagt agtacttttt
    65161 gtattttcaa tgtctaaagg tatattatat ttaaacatat gctcacttca aaattaagcc
    65221 tacagtacta ttatactcaa acttactact agattttagt accatgtatc cttctacttt
    65281 gcttattaac ccataataat ataatctatt aaatataaac cctgatactt gaatcgaatc
    65341 ttgttgtaac tctctatctt ccttataaaa atcttcttcc agaataattt tgtaactaac
    65401 atcaacatct ctaaaaattt tagctgcttc cttcttacta tcaacaatat ttttgtaagg
    65461 ttcaaaatta aaaattaaat ccaatccatc aaaaatttct ttatttatac cataaatatt
    65521 cttaatttct ttatcacaac ttataaaatt ctcttcaaaa tattttttga ctacactatt
    65581 atcatagtaa tcatccaaaa tagtttttct aattcccatt gtaaaaatag agttagtttt
    65641 taatatgtcc tttaagatgt ttttagttgt gttcttaagt ttgttatcat aaattttatc
    65701 ttcactaggt agaatataaa agtttccata ttcatattta ttatttctat tacatctacc
    65761 cattctttgt atcaagctat ccatagttgc taaatcactt attattatat tgaaatccaa
    65821 atccaaggat atttctactg attgagttga tatccaaata tcaccctctc catttaatat
    65881 tttactatat ttctcttttt tatctttgaa cttaaatcta ctatgtaaaa catctatatc
    65941 tacaccacca tacttatcag ataaattttc ttttaaaaac tcatatgttc tattgactga
    66001 atcaatagta ttctttatta taagaatttt ttgtttattt tctaaagcat cttcaactat
    66061 tgacttgatt tctttttcct ttataaaaga aacctttaca tctttacctt cacaaatctc
    66121 ttcttccttg ttgctctcaa taaaaactat ttctccttta tcagtaacat tttcattact
    66181 ttcttcttga aaaataattc ccttgtttat catttgctct ttatatgatt ttggaagtgt
    66241 agctgtcatt aagtgaaaat caacatctaa gtacttgcat gcaaactgca taaaatatat
    66301 caaaatcaaa aacatctttg gttccaataa atgtacttca tcaacagtta tagatgcatt
    66361 ttttacggct gcgaatattt tttcatatcc cggaaattta aacatactaa gtaataactg
    66421 gtcaactgtt gcaattacac aaggtttaca aaagtttata ctcaaatcta tatcccttaa
    66481 tgtcaataca aaatcatgtt ctccattatc ttcattctct gaatataagt ttatatctcc
    66541 atgaagtaat ccaatgtaat cattactact tcttgtatct aaatcatttt tattttgaaa
    66601 aatatttttt ctataaaaac tttctgctga tattttattt ggcactaaaa agaattttct
    66661 tttaaaagtc tttctataat ctgcagctgt ttttcctgaa cctgtaaatg caacagtcag
    66721 aacatttctt ccagaaagtt ctctcaacct tttttgtata gtattgaact ctatattatt
    66781 tttttccaaa ttaccctgac tcttatatat ctcatttaaa atcatattat caatttcttc
    66841 atcagtaaaa tcgttataaa attttatacc tttctgtcta cttgatgcac tatggtctat
    66901 taagttcagc atccctttat ataaaatata cttaaacttt ctataattta aaactgaatc
    66961 atctatttga ccattgttat aatcactgtc tataaacata ctttcactta atttatctat
    67021 gtaatcataa tccaatacat cttcaccaaa tttaaagtct acatttaaaa tgctatttat
    67081 ataactttct atatctttca gattaaactc ttctttttct aaaatgcctt tttcaatata
    67141 ctcataaatt tcttcttgaa ctttactaat acttaacctc atataatctt catagtttcc
    67201 atgatgtaac attatacttt tatatatata taacttatct tcttctgaca agttcatttt
    67261 ttctaatata tcttttaaaa atgctccaga aaatatatta tgtcttgcta tcttttttaa
    67321 agattttttg tcagactcta actttttcct ctcttcttct gagcaactat acgatatttt
    67381 attattaatc tccatttttt gttgcataat tgaattaatt tttcctaaat cgtgcaaagc
    67441 acaacatatt tttagtatct ctacatcttt atctgaatat agatttagtt ctaatataga
    67501 ttctaatact tcaaataaat ccttaatatg ttcaactaat gtttgctctt gttgattagt
    67561 tcttaaatta tatgacttag ctaatatttc tttttgcatg atatttttca tgataaacac
    67621 ctatctttca aaataattta aagccatgta aaaacttctt ttgtatcaat acatacattt
    67681 accttaatat ttttaggata tataccatca ttatcaacat atatataatg gcaaaactca
    67741 taaactctat catctctatt tgcttctaaa tctttatatt tataaggtaa tgcaatcaat
    67801 acaccttgat ttattatagt ctcgacattc tctttatctc ttaagtcaac tcttacatat
    67861 gtattcttta attttatatt ttcttttata gcatcacgag tattcatagg tataacctct
    67921 tttaactcaa cttctttcac aaaacaccct ttttcacttg gtattacaaa atcttctttt
    67981 cttcctaaat ttgcatattt acatggactt tcaagctttt ttctaataaa ttcaagttct
    68041 tcatcatcct tgcaagaaat aaatatagtc agttctactt ctttaagaac ttcatagttt
    68101 aatatgctat tttgagcttt atgttcttta tagtaatcat agtagtttcc ttgaagcaaa
    68161 aacttttctt tatctttgcc ttttctcata tttgtatatt cattccaaaa atcaatgttc
    68221 tctcctcttg aaaattctag ttctctatga tgatgtgttc caattattcc tatatctata
    68281 tcagagttta atcttctatc acataaatac gttatcattc ccattattgt ggtcttagat
    68341 ggtaaattta aagtacttat atattcattt tgaaatactt ttgggtctct atagtgagca
    68401 gttggttgct taagtttaca ttgtaatact ttcataattc aaaaaacctc ctactctttt
    68461 aaataccaca tattatcttc tccaatttcc aatctatctg ctagattttt aatctctttt
    68521 acagggtatt tacttaaatt aaacttattt aattcctttt tattagaaat ttttaatctg
    68581 tcattgatag caagtattgt gttactttct ttaaggctat aactttctat agtttctatg
    68641 actccctcta aatttatctc accactatca gcattataat ctacatcatc ccaaaaaaat
    68701 ggtacaactt tatcaaaagc tccacccatt actgcaagtg gttttaatag tactgatgaa
    68761 tgttttatgt ttcttgtaaa cacagtaatt gcatctaata tatcttttac tgctttttct
    68821 cttaactcct tactcataaa ttttctttct tctggtaaaa gtaactttcc atcttcttct
    68881 acttctacta ctcctattct atcaagctcc aatgttattg tataaacgta gtaatctgat
    68941 aaagtctctt ctattgctaa tgcttgtgtt gttggaaagt tttcatctct aagtacttca
    69001 ttttcttccc tctcatcata atattttcta ccaaattcgc tacttaaaaa acctctattt
    69061 gttatcaact gtgttgaacc tctatatgaa tttagtgacc taaaaggtat tattctaagc
    69121 ggagaagcct tacttataga acctttctct ttaagtggta ttaaataacc aaatacatca
    69181 gtctctaatc cattttcatc tacacatcct acatttttct taatagatgg atatatattt
    69241 cctttttttc caaaaacaat attacttaaa ttccaaccat attcttgatg gagtattctt
    69301 cttaaatcat atgttattgt agctatacta gtttttgcat gtactttatc tctatattgt
    69361 tcttttttta ttggtgtata atttccatac ccttggtcat acgaaagtgg aactgggctt
    69421 tctgtcagta tagttaatgt tactcctttt actctttttt cattcatttt aaattttccc
    69481 ccttttttat ttcatgattt cttgaataaa tagacctaca ttcgtattta attctaattc
    69541 agaactctgc attagacctt ctacaaaccc ttctcctatt aagattccat tagaaactaa
    69601 cacatgcatt atagtttgaa atagctgagt tctatcatta gacttaagta gttgaatcac
    69661 tttcatagaa aaattttttc ttctggattc atctgtcatt ttattaaata agtctttacc
    69721 tactcttgaa tatattaaat tactttctat atagtttttc attttatact cctcccttcc
    69781 atctacaatc caacacaatt ttatatataa accgatatta tatgaactag atacaaaatc
    69841 catttctcga gaagttccag ttagttgcct taaaacactt atattatcaa gtaataattc
    69901 ttttaaattt gataaattcc cattattaat cattttttta cccaaatttc tagtattcat
    69961 tggctctctt gaaaaattat aattatctat aatatctata agttcaattt tttttaataa
    70021 ttctttatac tctataatag agtcaaattt tagaattata cctttattcg tatcaatatc
    70081 aatcctatat agtctaattg aacttatttt ttcatgcaaa agttttttat aaaatgattt
    70141 atctgaatac atttttcttt taagcattat cttatgattt aaaaatgcta attctcttaa
    70201 atcattcgta tatgcaaaaa ccattggtct ttttaaattt atatataaaa gacacattaa
    70261 gttgaaaaat tcacactcaa aacaaatatt actttcaact tgtccacttc ttttaaaacc
    70321 tgatttttct gcacctctaa ataaaaagtt atacttagag tcctttcgtt ctcttaaatc
    70381 aatatctagt tttgttgttt tatttatatt gcaaacatta catacactat ctttttcttc
    70441 atattgtttc aaatcaagtt tatctatttc atctatctct atatttgatt taatcacaat
    70501 atcgactatt ctttttacat ttttttccat attttctaga ctcgtgttta atccatactt
    70561 accactattt ctaacatatg gaaatcttct gtttttaaaa tcttttttaa tcccttcctt
    70621 ttgtttctca gttgcagaag atttatccaa ttcttcaata aaatttacat atgttaaatt
    70681 atctatatta ctaaatattt tttctaaggt ttcctttttc ccatttttaa ataccttaaa
    70741 aagttgattt tctaatatat aatcagatat atacttaggg tctatatatt ctgcagattc
    70801 taaagataaa taatttctat tcaactcaca agtaaatttt agcttataat catttttttc
    70861 tagttcgttt tttaaatcca ttagtaattc acaaaagtaa acaatgccaa tatctcttac
    70921 aatatcacct gatctataaa atttagcttt tatttctctc acctcgctac tttaatatat
    70981 caaccattcc tgcattttcc gtccttctat atccaattcc cattttatac agtgcattta
    71041 aatcttccat atttcctttt aaaaaaaatg ttcctgcata agcatttata tagtaaaatt
    71101 ctctctcttt aaatccacga atcttttctt ttaacactct ttttttgaag ttaagaggta
    71161 taaattccaa tggctttcta agcccactac ctcttatact ctccagagtt agattagcta
    71221 tatagtttaa acattctata taatttgaat cttctacatc taaatattta ccttctttat
    71281 tctttactat tataggagac atagttttaa atataacacc attttctttt atctcgtgtt
    71341 ctttatgtat ttttatattt tttattttaa atctataacc tttatattct agctccttta
    71401 cttttaaaat tccattgtat aatttactga acatagaata attataaaaa cttatattga
    71461 atattatatc tccatcaaca agtaactcat ttttgcttct tataagattt ggtatgtaaa
    71521 tggctgtatt tatatccttt atttgcttat tgttttttct ttcttcccca tagttaaata
    71581 tgtttttagc aaaatctttg ttttctgcat ttaaaatatt ttttataaag gaaactgaca
    71641 acattgaatt ttcatttgga aatttgccat tacatgattc cataaaaatt gaaattctgc
    71701 tcatattttc acctcctact ttctagtata attcattatt ctctatttgt aatataaaaa
    71761 attaatagat atatatctat taatttttta tatctataag atatctaata atacaatatg
    71821 gatatgtaca aatctatatt tataacaact tttgttacta tcaaaacaga aattgcatat
    71881 atagcatagt ttaatatttt ttttgataat atatttaata ctatttctgt aagcttcttt
    71941 aaaacaggct taactatttt ctcttttttc ttcaaattca tttaaaattc cctctttctc
    72001 tttttata
//
LOCUS       DAEPKC010000007        71731 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.007, whole genome shotgun sequence.
ACCESSION   DAEPKC010000007 DAEPKC010000000
VERSION     DAEPKC010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 71731)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 71731)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..71731
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.007"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            479..1750
                     /gene="serS"
                     /locus_tag="KR294_000555"
     CDS             479..1750
                     /gene="serS"
                     /locus_tag="KR294_000555"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HBH0238672.1"
                     /translation="MLDIKRIRENLDCIKKAMERRGEKNFNLDEVVKLDDERRKTLQE
                     VEVMKNELNTASKNIPNLIKEGKDVENEKIKLKELSDKIKVIDQNLKEVEDKMEYLLM
                     RIPNVPHPEVPQGETDEDNVEVRTWGKTTTFDFESKAHWEIGTELGILDFETASKITG
                     SRFTLYKGLGARLERALLNFYLDTNTKVNGYTEVIPPFMANRNSFLGTGQLPKFEEDM
                     FKIEGMDYFMIPTSEVPLTNIHANEILKFEQLPINYTAYTPCFRSEAGSAGRDTRGLV
                     RQHQFNKVEMVKIVAPEESYNELEKLTNNAETMLQLLNLPYRVVKICTGDLGFTASFK
                     YDVEVWMPSYNRYVEISSCSNCEDFQARRAGIRFKRDKDSKAEYVHTLNGSGLAIGRS
                     VAAILENYQQEDGSVVVPEVLRPYMGVSVIK"
     gene            2118..3623
                     /locus_tag="KR294_000556"
     CDS             2118..3623
                     /locus_tag="KR294_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBH0238673.1"
                     /translation="MKIQNTEWGYIEWKHTYDENNPKQAMNIYIAVTMPGKKHFNHVH
                     YGQEQMIYILEGEGLYIINGVWKPFYQGMIFYIESGSTHETINTGDREIKELIVSNNV
                     DDVGESEVIDINPNNYLKKTLINYSESTLNLYAAVESIRGQFIDPFKIPLIIYDDSWN
                     IVLKNPYFPLFCFEKCNPMKFPQNCDCMNQKSSNQFVCEYGITIYNIPILYKSNSIGV
                     IRGGYVLLSDLNLDTEHNNLYDIPEGAARSIKRLLKQISKNIINFCSFNDIRKDLQEK
                     EKTIARTYHYGEQLEMNLKVAQDMVTNLRINHHFLFNTLNSMASIALDDGSYDLYSAI
                     IDLSRMFRYTMRSDLRFVELESEILYIKNYLNLQKLRYGDALKVKYLIPEKLYNLSVP
                     FNFIQPIVENAFTHGFRDIDTEKRIEIIARLDSQYAIIEIHNNGTILDGNNIDKIKAG
                     IRSNNGHGLSLIYTKFTSAYGNNFDMDIKSSDNEGTYIMIKIPIENYKEYV"
     gene            3737..4435
                     /locus_tag="KR294_000557"
     CDS             3737..4435
                     /locus_tag="KR294_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBH0238674.1"
                     /translation="MRRALIIDDEEAVLKIITHFIEMKDMPIKIVGKATSGDEAVDKI
                     IGLEPDIVFIDIQMPIYNGLEVIEKTSHLSKKINFVVITAFNYFEYAQKALRLNVKDI
                     LLKPLDMKEFTKSVEKIIGYQYTNNDLLNEILEYINLNYSNDLKLNDCARLFLTNPSN
                     ISRIFKSNLNTTFISYLNHIRIEKSIELLENTTKSINEIAEIVGYNSLNNFYKNFKIE
                     KGMTPKVYKLNTKN"
     gene            4720..5808
                     /locus_tag="KR294_000558"
     CDS             4720..5808
                     /locus_tag="KR294_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0238675.1"
                     /translation="MSDKVNMKNIICIAGAYLATAIGSGFATGQEILQFFASQGYMGL
                     IGALISMVLFSFLGAEVITRGRELKLKEPTRIYTFYCGKILGKFYEWFSPIFLFGILI
                     VMISGAGSTLTEYYGINPYLGRVLMAVATLITVSMGLEKLVSILGRIGPVIAVFTIAV
                     GLISLFKHFDGLSMVGEAMKNIEVTKASESPIVSGVIYNTLNIIVMIVFLTGMGASIE
                     SKKDAFWGGLLGGIVFMTAGIVMYLAMISDIGNLYMKEIPSLYLADNISPIVGVCFSV
                     ALILGIYTTAVPLLWSVTNRIVEDEHPKFKLVTTVIAILACIGGFLPFGKLVNILYPY
                     TGYMGLLILVCMVYKAITCRKKSTQSQE"
     gene            6047..7237
                     /locus_tag="KR294_000559"
     CDS             6047..7237
                     /locus_tag="KR294_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH0238676.1"
                     /translation="MHELILISEKYKEDILDFFTDIHMHPELSFKEFRTTKAIKDLLV
                     SLDIEILDLGMETGVVGLLKGKYDGPTVALRGDIDALPIYEEVDIKYKSRYDGIMHAC
                     GHDIHTSCLVGCAYVLSHIRDSLHGNVKFIFQPAEEVNKGAKMLVERGVMENPKVDAI
                     FGLHNHPDIPCGKIGVKLGGLMAAVDTIKIEVNGFGGHGGIPNRTIDPIVASSAIIMG
                     IQTIVSRNISPLESAVISIGTINGGTANNVISEKVDMTGTCRSFSNEVRKKISENLEN
                     IVCEIARGYQATAKLDYLFDLPAVINSKEMYAIACKSVCDLYSEDAIVDPIPSTGGED
                     FSIFMEKAPGFFYWLGVGNKEQDCIYQWHNPKFKADKNSILVGTNVLCQSVINYMDKL
                     KNKI"
     gene            7328..8830
                     /locus_tag="KR294_000560"
     CDS             7328..8830
                     /locus_tag="KR294_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbgT family transporter"
                     /protein_id="HBH0238677.1"
                     /translation="MRALNVVERAGNKLPDPVTIFLLLCIIVVILSAVISNLGVEEIH
                     PSTKEVVKVVNLLEKEQIQSYLGSIVTNFQSFAPLGLVLVTMLGAGVAEKSGFMEVLM
                     KKGISKVPQKLVTVAIVFAGMLSHTAADVGFIILPPLAALVFLGIGRHPLVGMFAAFA
                     GVAGGFAANVMLSTTDVLLAGFTIPAAQMMDPSYQGNPAMNLYFAFISAIVLTFAGAF
                     VTEKFIAPRFTKYNDSTNDKDIQELSELENKGIKYALLSLLVVVVVIVALCIGDNAFM
                     KDPETGSILSSNAPLMKGIVPIITIIFLTPGLVYGKVSKKIKSDKDLVSMMGSSMSDM
                     GGYIVLAFIASQFINLFNLSNLGTILSITGAKLLAESGIPSYGLIIGFILLSGFINLF
                     VGSASAKWAILAPIFVPMFMLLDFNPALTQIAYRIGDASTNPISPLFPYFPVILAFAR
                     RYDKDIGIGTVISNMIPYSVVFTLIEIIILLLFMGIGIPLGPGGGISYVL"
     gene            8902..10158
                     /locus_tag="KR294_000561"
     CDS             8902..10158
                     /locus_tag="KR294_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HBH0238678.1"
                     /translation="MLKTTKISDPELYKIVADELVRQEHNIEMIASESTAPTEVLELS
                     GCVFTNKTEEGYPGARFQAGSEEADKLETLAIKRAKEVFGAEHVNVQPYSGSTANYCV
                     YSSILKPNDTVLSMRLDQGGHLTHGSAVNFLHDIYKYEFYGVDPNTGRIDYDALEAKA
                     KECRPKLIIAGASSYPRLIDYERISKVAKEVGAYFMVDMAHVAGLVAAKVIPSPVPYA
                     DFVSSSTTKTFCGPRSGIVLCKAEHAKKLDKGVFPGTLGSIHLNTVAAKAFSLLYLST
                     DKFKKIMEQVVVNAQTLASELISHGFSIVSGGTDNHIVMVDLRSKNLTGKQFEKALEY
                     VGITVNKNVIPDDPQSPFVTSGVRIGLTSISQRGLKEKEVIQIAGIMNKVAENIDNKE
                     VLDECKAEAQELISKFPLYPEGYFED"
     gene            10330..13104
                     /locus_tag="KR294_000562"
     CDS             10330..13104
                     /locus_tag="KR294_000562"
                     /EC_number="7.2.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-translocating P-type ATPase, PMCA-type"
                     /protein_id="HBH0238679.1"
                     /translation="MRYYNKPTKEVLKYLKTNPEIGLDDNEVEERKLRYGLNEFTIKE
                     GRTFWDELGESLTEPMILILIGAAVISSFVGELHDALGILGAIFIGISIGIITEGKSK
                     KAAHALSKLTENIEVKVLRNGKIIKISKNDLVPGDIVYIETGDMIPADGRLIQSINLK
                     LREDMLTGESDDVAKNADAVLDMEVVYSKTEIIEQDAIPAKQVNMVFGGTLVAYGRGI
                     MVVTHTGDKTEMGKIAQNLSNEDQQTPLQIKLGKLGAKIAGISGVIATLLCMFMIIQM
                     QRKGMLILDTSSVLSFLQSLEPAKNAYMVCIALIVATVPEGLPTMINITLAITMQKMA
                     KINALVTKKEACETIGSVSVICSDKTGTLTQNKMMVEVAYVDGKYISGGEYQSNSYFE
                     QNCIVNSTADIEKEDNSFKYIGSATECALLLYHNDKNYNEMRKQTYLISQIPFSSEEK
                     KMSTLIRQEDSDILLSKGAPEVLLKKCSYVQQGKNIVPITPKVEKSILDEIKKLQIKS
                     MRTLGFAYKKMSNSKTEVAMTSEGELNLIGNSRSYMKEDNLVFSGFVGIVDPLREGVK
                     DSIDKAFNAGVDVKMLTGDNINTATAIGNELGLLNDGKKAVEATYIDVLTDKELREEI
                     KGISIVARSKPDTKMRIVSALQKSGEVVAVTGDGINDAPALSQADVGIAMGISGTEVS
                     KNAADIILTDDSFSTIVEGIKWGRGIYENFQRFIQFQLTVNIVAFIIAIISQLTGKDM
                     PFTTIQLLWVNIIMDGPPALALGLEPVRDYVLKRKPINRHSGIIARSMFVNIIINAIL
                     IITIVFTQSAFNILGATSEEQGTVIFSLFAFSALFNALNCREFGLNSTIPNFFKNKLA
                     LQIIVVTGIIQIIFTQVFQSFFNSVSLDFDMWIKIILFASTILLSNEFVKLILRTMKN
                     SRTMNFNSKN"
     gene            complement(13205..13354)
                     /locus_tag="KR294_000563"
     CDS             complement(13205..13354)
                     /locus_tag="KR294_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HBH0238680.1"
                     /translation="MFFISYIYTKSPIEFDTPLQKEAYKILQKLDIDFECVDTDEAIT
                     MEDCV"
     gene            13729..14907
                     /locus_tag="KR294_000564"
     CDS             13729..14907
                     /locus_tag="KR294_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBH0238681.1"
                     /translation="MFSKILVKTFIRDSENVQNTDVRNKYGYVAGVVGILSNLLLFVI
                     KVFIGMLTSSIAIMADAFNNLSDMASSAITMIGFKLASKPADKEHPFGHGRIEYLSAL
                     IVAFMVMLVGLQFVKSSIERIVNPIPVKFEVIPLILLIASIMIKIWLSRFNKFMGNKI
                     DSSALKAVSLDALGDVFTSSCVVISFIVARFTNFPIDGYVGIVVSLVILYAGFSLVKD
                     TINPLLGEAPDEEMVNSIIELLLSYKYIIGTHDLIIHNYGVGRCIASIHAEIPSNIDI
                     MEIHEIIDTAEREISEKLDIYLVIHMDPICLEDKEVMSAKKELEEILKKNSLVKSMHD
                     FRIVGKGSKKNLIFDIVVNPSEFSKNMSEDDLKEDITKLVKEINPEYNCVIVVDKDFI
                     "
     regulatory      15034..15119
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            15237..18155
                     /locus_tag="KR294_000565"
     CDS             15237..18155
                     /locus_tag="KR294_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021362860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SrtB-anchored collagen-binding adhesin"
                     /protein_id="HBH0238682.1"
                     /translation="MKKGNRKALLISLIMILSMVVSTIYPTVSYASELGENSQIQSGS
                     TNSSTGEEKESDNKKPEQTPEKDKATDNKKPEQTPEEEKPTDNKKPEQTPEEDKSTDN
                     KKPEQTPEGEKPIDNKKPEQIPEEDKSTDNKKSEQALEDEKPLDNKNTEKTPEEDNLL
                     EDENLLKVLEEELNEENEDYGFVVKINNNTIETESMKKISFNLTYTPTSKGIQAGDSI
                     TFKVPDVFNKVNLDYTSECFDKTESNGEYTLTFRELPNGQSVMQGKIGLEAYVKKVDE
                     DTNAKIHIETTGKIESGSGDIDVEIKPGDKTDVPDAKGTLKKLVEGKKSTTVFMPVKN
                     KDINYSIQVNEKQEELKDIILYDELPEGLTLINGSVSVVTSDGKEVSDFNIEQSKNSI
                     SVNFGNIDKSYTVKYKARISDKNAKHGNKYKNVARIESDGKKIQEDDATVSIFDRGDD
                     YLLTKGHSGATNITQVGQVINYQISINDDKSPISNVVITDNIPEGMRLTTSGEAGHDF
                     RVVEIPMNGSWTPWSKEKIANNISYKVEEKRNESGQVDKVITGFTINLSKEEVESKFF
                     IAYTLKVISIEDSYINRAVLDANNSEIDKNDEINFKKNSGLISAKKEVDKKVLNSSDN
                     QIVKYKINMSTYGVYDAGQVNLLDEVNSALEISNIKYSDNLELKKEAGDGKNTIRLVN
                     KYEFKQIKEGEPVQSWVTFDADFTNVKVGETIQNVAQINGSSPPGVETTKQGYAFEAK
                     KVDALDKNVLSGAKFNLEDAFGNIVVKDLVSDEDGIIQSSIKKPGTYYLVEIMAPSGY
                     EKLKDKIKVEIGNKDIGRIVDIGNIENIRQENPPVNPPAPPNTDEPIVNPPVPPSTDK
                     PRKPSSSSDTEDTIVINPPIPPSEDIINPPIPEVLNPPVPPSEEMIETPVKQIIPIPE
                     VVKPSVSEEKNNKVKDDTLVNPPVPPKTGDSTTIIGEILLVIGAIVGLIVLRRNKNTN
                     "
     regulatory      18341..18426
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            18526..19188
                     /gene="zmp1"
                     /locus_tag="KR294_000566"
     CDS             18526..19188
                     /gene="zmp1"
                     /locus_tag="KR294_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease Zmp1"
                     /protein_id="HBH0238683.1"
                     /translation="MRPSKKLLIAIISIFLISSVPVSAHADSTTIQQNKDTLSQIVVF
                     PTGNYDKNEANAMVNRLANIDGKYLNALKQNNLKIKLLSGKLTDEKEYAYLKGVVPKG
                     WEGTGKTWDDVPGLGGSTVALRIGFSNKGKGHDAINLELHETAHAIDHIVLNDISKSA
                     QFKQIFAKEGRSLGNVNYLGVYAEEFFAESFAYYYLNQDTNSKLKSACPQTYSFLQNL
                     AK"
     gene            complement(19310..20272)
                     /locus_tag="KR294_000567"
     CDS             complement(19310..20272)
                     /locus_tag="KR294_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HBH0238684.1"
                     /translation="MKKGYVYIILTTLFFSSMEISLKTVTNDFNPLQITLSRFFVGGL
                     VLLPFAVKRLRALSLSITKSDLKYFAFLGFMCVVVSMSLYQLAVLNTKASVVAVLFSC
                     NPVFVMLLAYLILKEKIYRHNVISLILEVLGIIVIINPLHTKLTLSGIFLTLSSAIIF
                     SMYTVFGKRKTLKFGGIVVTCFSFIFGSLEMLILVLLTKINFIADILNKNKLHVFANI
                     PIFSGYTLHNMPIMIYVFVFVTGVGYALYFMAMEATSTSLTSLVFFFKPVISPILALL
                     ILKEIIPINMVIGILLIVIGSIISIIPTIITQMHNKHVEALYKE"
     gene            complement(20442..21632)
                     /locus_tag="KR294_000568"
     CDS             complement(20442..21632)
                     /locus_tag="KR294_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBH0238685.1"
                     /translation="MISNKMQTLVANSSVIRAMFEEGKKLSDIYGEENVFDFSIGNPS
                     VEPPETIKAVINDILNEESPNLVHGYMNNSGYEDVRDAIAEHINKKDGLNLTRENLIM
                     TCGAAGGLNIILKTLLNPGDEVIAFAPYFGEYKNYTENYDGKLIEVPTNIETFEPDLD
                     ALKNAITPKTRALIINTPNNPTGVIYSEELLKNLGELLDSKQKEFNTSIYLISDEPYR
                     EIIYDGAKVPCVLKYYRNSFIGYSYSKSLSLPGERIGYIVANGQMDDFDDVMSSLNVA
                     NRILGFVNAPSLFQRVIARSLDAEVDVNIYKKNFDLLYNSLIDMGYSCVKPNGTFYLF
                     PKAPIEDDKKFCNDAKQFNLLLVPGSSFGCPGHFRVSYCVSYDKVKSSLPAFEKLAKL
                     YNLK"
     gene            21938..22384
                     /locus_tag="KR294_000569"
     CDS             21938..22384
                     /locus_tag="KR294_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBH0238686.1"
                     /translation="MDFKNLQYESLSYIICNLQKNFKLYCEKCLKPYKLTNGLYFYLI
                     YINKNRNCSLNDVSTEFEVDKAHTTRTISRLEQDGYIEKIQNPNDSRAFQLRVTDKGE
                     EVLGDIKNIFSKWDNHIKKEFSDTEYKELVKNLHVVKDIKTAVEEE"
     gene            22386..23480
                     /locus_tag="KR294_000570"
     CDS             22386..23480
                     /locus_tag="KR294_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH:flavin oxidoreductase"
                     /protein_id="HBH0238687.1"
                     /translation="MYCNLLKPIKIGNLELKNRVSFAPTSMGLKLEEKIKKFSDIAKS
                     GVALITLGDVSIRPSFHKVAISLSDEDGVMKYKKIVDEIHNSGAKVSAQLFCSDYDVN
                     LIKDTMNMGITSHDEIKKIMNDGVKDYITNMPKEEIKNIINLFKVTALNAKKAGFDMI
                     QIHGDRLVGSFSSSIFNNRNDEYGRTCDNRSRFASEIISSIRDEVKDIPIDYKFAIRQ
                     ENPHYGNAGVLLSEVEYFVKKFESLGVNSFHVTLANHSKLEDTIPTNNHPYFKEEGCF
                     LYLADEVKKHTNLPVCGVGKLSSPDFIESIISNNRVDMVSMSRQLLADRNWLQKVKDG
                     RVDEIKKCCYCNKKCADALQTRSQFGCILD"
     gene            23568..24098
                     /locus_tag="KR294_000571"
     CDS             23568..24098
                     /locus_tag="KR294_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBH0238688.1"
                     /translation="MKSLVLYSSLTGNTKKIAYTIYDEIQEEKDIKDVNELVDYSIDY
                     ENYDIVFLGYWVDKGICDKNSKQVLENIHNKKIALFGTMGASKKGSYGASIIEKIESI
                     IPKDNEILGSFICQGKIAEGLKAKYKEMLKLSPDNEHIRQQLNNHEESQSHPDEQEIY
                     EASMFAKNMMIKASIV"
     gene            complement(25035..26411)
                     /locus_tag="KR294_000572"
     CDS             complement(25035..26411)
                     /locus_tag="KR294_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0238689.1"
                     /translation="MKYKIGFLTTSYFMSDKFKQALKELNDTCEITFIELKGENPFNN
                     LPNIYYEQVDNFDGFVCSGIVPYSELIINIKDIKVPLNFLKLDERDFYKYLFKLLNSQ
                     KDIDFTKSFMDFLREDNNYYDIYSLIDSNKCPYTIKDFNIPQPVYDFKKLNDKLLEIH
                     LDLLRDNKINLSFTRNYIISCELNKLGYDCIYMVPSTESILNTFKSLVNEITLQNLDK
                     NKSATCIVTVNSSEYINEDLIFKNDEIQNQIYNTILNSLSRHGFYGVQVKKNDMKIEI
                     HTTKEMLNNMTNNYTDFFISEDLKEIKYSLNIGWGIGNTNIHAEQNARQANGKSASLN
                     GNCTFIVNDTNDTIGPLYSNKNSNNIEDSSIANKVASFIPLSNTNVSKIMCMINDRNS
                     NNVSAEILSNYMNITLRSANRILSILYKAGIATIVNTKLDNQRGRPKKIYKVDFLSFL
                     NKMQKLNS"
     gene            26679..27851
                     /locus_tag="KR294_000573"
     CDS             26679..27851
                     /locus_tag="KR294_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBH0238690.1"
                     /translation="MNTYLNEISKFVDENREEIVSLWKEIVNIESYTHCKESVNKLAK
                     RLKFEFEKEGLDCELVDVGDNGSTLIGTLGSNINKKPIIFSGHMDTVFETGTFGENPF
                     KIIEGKAYGPGVLDMKGGIIISLYVIKALNKIGYKERPIKIVFSGDEEIGHKDSTGAD
                     VILREAKGGLCAFNMETGLVDNSLCVGRKGRIGCNIHVKGVETHAGNDFEGGRNAIEE
                     MANKILRIQKLTNLDVGTTVSVSVIKGGRVENSIPEDCSIKVDLRFEKVEEMENVKEQ
                     VREICKETYIEGTSTEVNFISEMMPFETTEDVMRFHTFVNEVSKENGFGELNAKRLGG
                     SSDASYLTIANVPAICSFGVRGEWNHTSREYAVVDSMFERVKLISTVILNLDKFEV"
     gene            27865..28512
                     /locus_tag="KR294_000574"
     CDS             27865..28512
                     /locus_tag="KR294_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0238691.1"
                     /translation="MDVTAGDNKVTWKGYLSLFVLIVLFSGVFKDSQGFLKALDFANL
                     TGSFGTIADGVDFMGKGGTGAKDGFLFALTLIPTVCFAVGLIDVVESMGGMKAASKIF
                     NPLLRPLLGIPGIAGIAFVSSFTSSDVASIMTKELFESGEITDDERTIFVAYQYAGSA
                     VILNTINTQAPLLPIALLALGPIILIEIFCKILGANLVRLIIGVRNKKNKAKEAV"
     gene            28514..29023
                     /locus_tag="KR294_000575"
     CDS             28514..29023
                     /locus_tag="KR294_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside recognition protein"
                     /protein_id="HBH0238692.1"
                     /translation="MSQQNTGNAIVNSKPKKTAVEIFMGGAKKGFYIGVEQILPAMIM
                     GYVIVQFLQLTGLVDILGNIFGPVMGIFGLPGESVLVLIAAFFAKAAGAATAANLFAQ
                     GLITAPQATILIMPCMLMGTLVGHYARIVLVANASTKYRMLLLAVPIFDAIVGMLIVR
                     VLLTVMGLM"
     gene            complement(29387..30499)
                     /locus_tag="KR294_000576"
     CDS             complement(29387..30499)
                     /locus_tag="KR294_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HBH0238693.1"
                     /translation="MKISEVATPNFLLDLDQLEKNIDKIQQICTNNNKQLWPMLKTHK
                     STYIARLQKNAGASGFLVGTLDEGEALIKAGFEDIMLAYPYMGEVNINRIVTMASKIN
                     LICATDNIECAKAYSEAFSKSKIECKLLIIVDCGLHRFGVEPEKVVELATEISKLENI
                     KIVGISSHPGQVYGCSSPEGVPDVCVQEDSSMEKAYKALTDNGFNIEIVASGSTPTVE
                     SEAASKTITAVRPGNYVYYDAIQIGLGCATEDMCALTVVCTVISKNSSGYYLIDCGSK
                     CLGLDKGAHGNSSIVGYGRVCGHPELTIDSLSEEVGKIKVNGETDIKIGDRIRIIPNH
                     SCSTANLTSNLLGFRGDTIEKVIEVDIRENSKQIIL"
     gene            30797..31063
                     /locus_tag="KR294_000577"
     CDS             30797..31063
                     /locus_tag="KR294_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase family protein"
                     /protein_id="HBH0238694.1"
                     /translation="MNLEPKKLIEQIGKEKDKKDIWIVGGGDIVKLFMKDNLIDDYYI
                     YILPIILGRGISLFKSGIDKTNLNFKKASNIGELVKLEYSKKQK"
     gene            31308..33035
                     /locus_tag="KR294_000578"
     CDS             31308..33035
                     /locus_tag="KR294_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003496244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0238695.1"
                     /translation="MKLILSYLKNYKLLIVLNILAIFSFALVELGIPTIIAKIIDNGI
                     ANQNIAYIKQMGIVIVIISIIGVVGSILLGYCSAKVSTSVTRDIRNDIFEKSQEFSHT
                     EYNKFGISSMITRTTNDAFQIQQFVNILLRTALLTPVMFIISIIMTIRTSVELSIVLA
                     ISVPFIIIGVAIIAKVSQAISSKQQKGLDKLNLISRENLTGIRVIRAFGNDDYETERF
                     EKTNTYYANVSKKLFKLMSITQPAFFLLLNIAVLAVFWISSEKINIGELQVGQLVAFL
                     EYLFHAMFSIMLFSMVFIMYPRAEVSANRIKELLNEEPLIKNPENGIKDTENKGIIEF
                     DNVTFTYPDGEASVLKDISFTAKTGETVAFIGSTGSGKSTLINLIPRFYDVTEGSIKI
                     NGVDIREYDLKALRKKIGFIPQKSLLFTGSIANNIRFGKHKAGESELEYSAKVAQAYE
                     FISKKPRKFDELISEGGANVSGGQKQRLSIARAIIRRPEIYIFDDSFSALDFKTDAIL
                     RAKLKKETKDAIVLIVAQRISSIIDADKIIVLNEGQVVGMGTHKELLKNCEIYYEIAT
                     SQLKKEELE"
     gene            33035..34825
                     /locus_tag="KR294_000579"
     CDS             33035..34825
                     /locus_tag="KR294_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0238696.1"
                     /translation="MKKSKGFKKTIGRLLPFVKKYKFSFIIAIICIISAATMNALAPK
                     TEGLIITQLTKDVISIAKGVPGASVNFDYVTKILVILACIYFANAIFTYTSSFLLTNA
                     IQNTMRDLRNEVENKIRRLPISYFDSNSFGDVLSRISNDVDTISNALQQSFMQIVNSI
                     LVIILALSMMFTINIYMALIALFIIPISYFVSKFVVKKSQSRFSLQQNALGKLNGKVQ
                     EMYTGFNEIKLYGKEEDSIKEFKKVNQELCENGFKAQFISSMMNPMVSLVTYFGIAAV
                     AVVGSIYAVSGGITVGNLQAFVRYIWQINQPLSQMTQLSTVIQSSFAAIERVFEILDE
                     EEEIPDVENPVKIENVKGNVTFEHVNFGYGENSTLIEDLNAEVKSGQMVAIVGPTGAG
                     KTTLINLLMRFYDVKKGAIKIDGVDIRDMKRKDLRSMFGMVLQDTWLFNGTIFENIEY
                     GRFGATKEEIIQAAKVANVHHFITTLPDGYNMFLNEEASNISLGEKQLLTIARAFISD
                     PSILILDEATSSVDTRLELMLQKAMRNLMNGRTSFVIAHRLSTIRNADLILVMNNGSI
                     IEQGNHDELMEKGGFYEKLYNSQFADKESE"
     gene            complement(34987..35295)
                     /locus_tag="KR294_000580"
     CDS             complement(34987..35295)
                     /locus_tag="KR294_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0238697.1"
                     /translation="MFNKIYEKKEFIVFQVKKGYVVYNTRKSFEEGHTHLKHFEAAKT
                     AIDLAINKKIPRSKDGYYLTSLIRISDDGYYIDKLSELLYVREQKGKKEKYCNSGYQM
                     "
     gene            complement(35557..36105)
                     /locus_tag="KR294_000581"
     CDS             complement(35557..36105)
                     /locus_tag="KR294_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0238698.1"
                     /translation="MIFLNEDVVTNETIDKDYAIEEVRMACKHFGDLYFYFSKVLFEE
                     FGEDKTSEILRKVLFERSEERAIAMRERAHENGDELIADNIISTTDVPFLGWVPEFEE
                     LHCPYGASWLLRFEENPWFKKFASLYCDVTDTTVAEVFTGDTSHKITKNILWGDKSCE
                     RIYFHDDKVSEGKYTYGNKNCK"
     gene            complement(36208..36879)
                     /locus_tag="KR294_000582"
     CDS             complement(36208..36879)
                     /locus_tag="KR294_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH0238699.1"
                     /translation="MATFKRLQEQAYDYLKELILSGEMIENEIYSETKLASEIGISRT
                     PIRDALQRLSQDGFIDIIPSKGFRIHQITANEIVEIFQIRSAIEGFCTFLITSQYKEA
                     RAVETISKLKHLLDKQKDILLGDKNLNSFAEYDTLFHTTIVSYAQNTEFDKMFNNYMY
                     RIKKLALDSLSHEGRLETTLKEHTDIFNNIANGCIEDIYRTTLIHMETPKYINLEDFC
                     NNKLF"
     gene            37275..38180
                     /gene="garR"
                     /locus_tag="KR294_000583"
     CDS             37275..38180
                     /gene="garR"
                     /locus_tag="KR294_000583"
                     /EC_number="1.1.1.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxy-3-oxopropionate reductase"
                     /protein_id="HBH0238700.1"
                     /translation="MEGYKMKLGFIGLGIMGKPMAKNLLKDGCNLLVYDINKSAVDEL
                     ISCGAKYASVLEMGQECDIVFTILPNGTIVQDILFGMDGLAKTLKEGSIVVDMSSVTP
                     TESILCANKLKDMGLEFIDSPVSGGEPKAIDGTLAFMAGGKEEIYKKVEPFFNIMGSS
                     SILIGDNGSGSVTKLTNQVIVNLTIAAVSEAFVLAAKAGADPEKVYKAIRGGLAGSTI
                     LDAKIPMIMNRDFKPGGKISINLKDIKNVMQTAHNLDVPLPMTSQLLEIMQTLKVHGH
                     LEDDHSGIAQYFEKLAGVEIKKHNN"
     gene            38316..39698
                     /locus_tag="KR294_000584"
     CDS             38316..39698
                     /locus_tag="KR294_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HBH0238701.1"
                     /translation="MITGYGLLIAFVISIGILLVSIIKFKVNPFLALLITSIITGFMV
                     RMPINEISTTISTGFGNTLGSIGIVIGLGIIFGNILSESRATESIAKGLLAKTGEKNS
                     ALAVTTAGFLISIPVFMDAAFVIMMPIIKYVSRVTKKSLMVFVCALGVGTIVGHALVI
                     PTPGPLAVAANVNANVGSFILYSIIVAFPAALIGGWIYGKRFEKYPAYAIDENDREKN
                     LEQGKDSIKIEDDDSSKVPGFGISMFSLLFPILLILISNVFSMFLEKGSTMSGVLAFI
                     GDKNIAILLGILVAIGFLKKYINKPMGDVVIEAADSAGLILLITGSGGAFGSVINASG
                     IGNFLVDTMSGLSISVVVLGFLLSALLRISQGSATVALVTTSSILGPTILATGMSPVL
                     VGLAICAGGVGFSLPNDSGFWVLSRFSGLSVKDTLNSWTIGGTIAGVVAFIMVLLLSV
                     INGIIPLPGL"
     gene            39769..41205
                     /locus_tag="KR294_000585"
     CDS             39769..41205
                     /locus_tag="KR294_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HBH0238702.1"
                     /translation="MREVKPISIDILNTFKQVDEDRLNKLLADELKHLDRKIVVLDDD
                     PTGVQTVHDISVYTDWDKDSMEQGFNEKNSMFFILTNSRGFTVAQTTKAHKEISKNIV
                     DVSKKVNKDFIIISRSDSTMRGHYPLETNLLKSEVERLSEKLFQGEIIMPFFKEGGRF
                     TIDNVHYVKEGEILVPAGMTEFAKDKSFGYKSSDIGEWCEEKTNGKYKSSDMIYISSK
                     ELRELNIEAITEKLKKAEGFNKIIVNATDYVDVKVFTIAFIRAVNSGKEFMFRSAAAI
                     TKILGGVSDKELLTKDELVSKGNTNGGIILVGSHVNKTTQQLEELKNCKYPIEFIEFN
                     QHLVLQENGLKNEVKRVIKVVEEKISRGKTVAVYTRRERFDLDTNDKDKQLMISVEIS
                     DAVTSIIGMLNVRPNFIIAKGGITSSDVGTKALRVKKATVMGQIKPGIPVWMTGKESK
                     FPNMPYIIFPGNVGEISTLRESVEILMG"
     gene            complement(41391..42245)
                     /locus_tag="KR294_000586"
     CDS             complement(41391..42245)
                     /locus_tag="KR294_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0238703.1"
                     /translation="MSTFYIQFLYFVIYSFIGWCCETTYCSVLQKQFVNRGFLNGPFC
                     PIYGFGALAIVATLTPFVHTIPLLFLFSIIITSIMEYCTSFILEKIFNMTWWDYSKHK
                     FNIHGRVCLENSLMFGVLSLIVMLIVHPIVVDFINSISKNVLFIFAISIEIYFVLDLV
                     ITVHTILQLNGKLKQINLIIKELKDKKEYYKLITQETIENKLESLVENRLDTLEDRFE
                     ILKEKENYRYAKNRIDELKNKLNTLLSNHKLLHRRIIKAFPNISSNKHTDILNKIKEN
                     IKSIKKDK"
     gene            complement(42513..42836)
                     /locus_tag="KR294_000587"
     CDS             complement(42513..42836)
                     /locus_tag="KR294_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1540 domain-containing protein"
                     /protein_id="HBH0238704.1"
                     /translation="MERINCNVINCSHNNSHICYADKIFINGEKAHNDRHTCCSSFLD
                     ESIYSNLSSNVNNRNCEELVCTVKNCKYNKDGSLCTLDNILVAPETDRVNLYIETCCS
                     SFECK"
     gene            43039..43668
                     /locus_tag="KR294_000588"
     CDS             43039..43668
                     /locus_tag="KR294_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0238705.1"
                     /translation="MFEKKKKELFPWKISALILVGVFVLSSGVYIGTRLKHNGVQTGE
                     VVSTSANMNEKSKEAFGLNKNCEVWLQSEGENETNYKRTLTMAGIVPESLLDKTKSEI
                     VSYFKKEYPTKKIKSMDKNEIILVESKYSDNKDVQAMDVTIKGKYTIENDNGNIALYK
                     YDDSGSKTLVEKTKIRVDSLPKTVQDEIKKGVVMDTEEEAYSRLEDFAS"
     gene            44011..44520
                     /gene="ruvC"
                     /locus_tag="KR294_000589"
     CDS             44011..44520
                     /gene="ruvC"
                     /locus_tag="KR294_000589"
                     /EC_number="3.1.22.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="crossover junction endodeoxyribonuclease RuvC"
                     /protein_id="HBH0238706.1"
                     /translation="MIILGIDPGIAIVGYGIIEYKNSKFKVIDYGAVTTPAHMNISRR
                     LELVYKGIDTIVKNYNIDEVGMEELFFNKNVKTAITVAQARGVTMLACAHNGKPVYEY
                     TPLQVKQGVVGYGRADKAQVQQMVTSFLSLKKVPKPDDVADALAVAICHAHSNKLEKT
                     LKNIGGKYV"
     gene            44513..45115
                     /gene="ruvA"
                     /locus_tag="KR294_000590"
     CDS             44513..45115
                     /gene="ruvA"
                     /locus_tag="KR294_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HBH0238707.1"
                     /translation="MYSYIKGTVEEIYIDSIVVENNGIGYKINVSSNTIMNLQVGEAT
                     KIYTKLIVREDDMSLCGFVSREELKMFELLTSVSKIGPKVALSILSFASPAQLGAYIL
                     SEDIGKLSKAPGVGKKTAERIVLELKDKVDKNNIEFEPTLLSQKPTLISQDESVDALV
                     ALGYTLSESKEAVQKCKKDGMNTEAIIKKALTYIMSKSLK"
     gene            45223..46242
                     /gene="ruvB"
                     /locus_tag="KR294_000591"
     CDS             45223..46242
                     /gene="ruvB"
                     /locus_tag="KR294_000591"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HBH0238708.1"
                     /translation="MQGFEDENRIITSTMKMEDIDIENSLRPKTLEDYLGQEKSKEQL
                     SIFIEAAKSRNEQLDHVLLYGPPGLGKTTLASIIANEMGVNLRITSGPAIERAGDLAA
                     ILTNLNENDVLFIDEIHRINRSVEEVLYPAMEDFCLDIIIGKGPSARSIRLDLPKFTL
                     IGATTRAGMLTNPLRDRFGVICKLDYYTVDELSKIVLRSSSILDAEIQSNGALELAKR
                     SRGTPRIANRLLKRVRDFAQVRADGKITDKVAKDALELLGVDSLGLDFVDEKLLMTII
                     EKFRGGPVGLDTLAASIGEDRNTIEDVYEPYLLQLGFINRGPRGRVAMPLAYEHLKIP
                     YPNKK"
     gene            46560..47585
                     /gene="queA"
                     /locus_tag="KR294_000592"
     CDS             46560..47585
                     /gene="queA"
                     /locus_tag="KR294_000592"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HBH0238709.1"
                     /translation="MKTSDFKFDLPQELIAQVPIEDRASSRLMVLDKETGNIEHKVFR
                     DIIEYLNPGDCLVLNNTRVIPARLIGEKLETGGKIEFLLLKRTEEDTWQALVKPGKRA
                     KVGTKFSFGNGKLIGEVVDLSDEGSRIIKFHYDGIFEEILDELGNMPLPPYITARLDE
                     KERYQTVYSKHNGSAAAPTAGLHFTEELLNKIKEKGVDIAFVTLHVGLGTFRPVKVED
                     VLNHKMHSEYYMVSQEAADKINRAKENGNNVICVGTTSCRTIESACNEDGKMKETSGW
                     TEIFIYPGYKFKVLDKLITNFHLPESTLIMLVSAICGKDNVLNAYNEAVKERYRFFSF
                     GDAMIIK"
     gene            47597..48082
                     /locus_tag="KR294_000593"
     CDS             47597..48082
                     /locus_tag="KR294_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0238710.1"
                     /translation="MHSLQKQKKNNPILKIAFIFERVLAVVVLIAVFLGTIDVLRLMW
                     GAYIVDFQNPVQYSQLNDFLAQILLLVIGVELVVMLSLHIPGAFIEALLYAIARKMLL
                     LPKNEGMIDVLIGVIAIAGLFAIKKFLVTKDKSALNIMSIHDEEAIKEQQNKEDEDKS
                     I"
     gene            48161..49282
                     /gene="tgt"
                     /locus_tag="KR294_000594"
     CDS             48161..49282
                     /gene="tgt"
                     /locus_tag="KR294_000594"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HBH0238711.1"
                     /translation="MYAVRYELIKTCKQSGARLGRLHTPHGIIETPIFMPVGTQATVK
                     SMTPEELKEIGSQIILSNTYHLYMRPGHELIKRAGGLHKFMNWDKPILTDSGGFQVFS
                     LGPLRKIKEEGVEFRSHLDGSKHFLTPEKAMEIQNALGSDIMMAFDECAPYPSDREYV
                     KNSLERTTRWLKRCKDAHNNTDKQALFGIIQGGMYKDLREQSAKEITNIDLPGYAIGG
                     LSVGEPKPLMYDVLEHTTPLMPKDKPRYLMGVGSPDDLVEGVIRGVDMFDCVLPTRIA
                     RNGTAMTSQGKVVVRNATYAEDFTPLDPECDCYACKNYSRAYIRHLIKANEILGARLI
                     TTHNLHFLLNLMKQIRQAIMEDRLLDFRNEFFAKYGYEI"
     gene            49416..49709
                     /gene="yajC"
                     /locus_tag="KR294_000595"
     CDS             49416..49709
                     /gene="yajC"
                     /locus_tag="KR294_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HBH0238712.1"
                     /translation="MPQQQIIMSIGLWVVVIAIFYFLMIRPQKKKDKQLKEMRSSLSV
                     GDKVITIGGIVANVAKVEDDVVILELGPNRTKVPFEKWAIGTVKSKKEEIEED"
     gene            49767..50129
                     /locus_tag="KR294_000596"
     CDS             49767..50129
                     /locus_tag="KR294_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04086 family membrane protein"
                     /protein_id="HBH0238713.1"
                     /translation="MGKSNYIFKGLGYAYIITLAVLLVYNLFLTFTDIGGDNITMVSS
                     FITTISAAIGGFYTSKHMKEKGLMYGLLVGLLYIVCIFLTVFLAQEKFVFEVGMIYKL
                     LLISAAGGIGGVLGVNFK"
     gene            50195..50338
                     /gene="scfA"
                     /locus_tag="KR294_000597"
     CDS             50195..50338
                     /gene="scfA"
                     /locus_tag="KR294_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="six-cysteine ranthipeptide SCIFF"
                     /protein_id="HBH0238714.1"
                     /translation="MENKHVKTLSQATLKQSAAKGGCGECQTSCQSACKTSCTVANQE
                     CER"
     gene            50964..52859
                     /locus_tag="KR294_000598"
     CDS             50964..52859
                     /locus_tag="KR294_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp8"
                     /protein_id="HBH0238715.1"
                     /translation="MLSNKKRSMAIVMAGATVMSAAAPIFADNTVTENVDKNYTVSAK
                     DSAKLIEEVRKALEVKFEDTKAGANVNDRVYDIKVDNVNLTNATQLQNKINSLTEGQS
                     LKVTIQDKGHQVLGGKVVDYKIENYKTAQEIVDAVNAYNATLAEDSDNKLTATIKSTN
                     TVEVKRAKDSANVITLNVGDQHLDFSKVITSEEGTFEGYEKSYSDIDSKELHTITVKN
                     ADLQDISAEELFDGIRLTTLGREIVNKVKNGYALTFENEAILTQEQEDSDDKDKPEKS
                     SFDIVLSKANEKPETISVSSKNHKLVRDLHKVLTDVKDGKELKVEVLSGDSRFTTAVE
                     VSKERFKDGEAEAIILVGEDAIVDGLASAPLASQKNAPILLSKKDSLPSEIEAEILRV
                     LGSNLSSKKIYIVGGESKVSKETEEKLSKLGVSKVERVSGEDRFETSLEIAKQLKDTF
                     KTAFVVGGNGEADAMSISARAAQFGAPIIVTGNELDANAEKLLKGKELEIVGGENSVS
                     KEVEDKLVDIDLNNKVERLAGENRKDTNAKVINKYYAGATKAYVAKDGYVGGNGQLVD
                     ALTAAPLAASSKAPIVLTTEELSKSQEEVVELRLKNATKLVQIGEGIAKNAIEKIAEK
                     INLFTKN"
     gene            53321..54724
                     /locus_tag="KR294_000599"
     CDS             53321..54724
                     /locus_tag="KR294_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp9"
                     /protein_id="HBH0238716.1"
                     /translation="MKNSKKILAIGLTLFLVMVNTPMVNALTSVEQIKGNDRYETAAK
                     IADKQNYNTAILINSDNSLADGLSASGLAGALNAPILMTKQNQIPNTTMERLNKAKTV
                     YIIGSESTISKNVENQLLSKKKVVQRIFGENRFDTSIKIAEKIKEIKPIDKVIIANGF
                     TGEVDAISASPVAARDGVPIILTDGNSVGFDTTGLKSYALGSSEIISDELVKSTNSIR
                     LGGTDRFETNKMVIQEFYKNSKEFYLSKGLQLTDALVASTIAKNAPVVLVENGSNKSI
                     LSGADKLTVLGGINQNVIKQCINQASPNQQGLYYNPNDRAFKERIKGKVYALTKHYRK
                     ENGVRALSVASRLEGLANDWSNLMANKKTLSHTINGKNSYSTFLKYLDWSEIKPGYIA
                     VQGENIIKYKIPDKPVYTNRDADDIGNFIFNEWKTNPEEGTNMLHKGYEIMGFGIAIT
                     GDKNLYATHEFYGRYKE"
     regulatory      54896..54981
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            55105..61053
                     /locus_tag="KR294_000600"
     CDS             55105..61053
                     /locus_tag="KR294_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-binding adhesion protein"
                     /protein_id="HBH0238717.1"
                     /translation="MKKAISCVLAVSMCSAPLNVFAEPILEGKLRAVEKSVTEKLRGS
                     LEVDLNFSLPIKNSESESMTNMQLRLKDDSNNSGIIKLGEKDSGTVNVGTDNIEYTIK
                     KLSASRSEIKNKDDNISYYNIVFNNLAVGKYNVEVSGDGFKNKEIKDIDISSYSQRVL
                     LSNRASVDNKNKPLNYELFLMGDVNGDGKVDKSDYNKVLENIDSNKREFDLNRDGKVD
                     IVDLDYVQKNLGQSEDAKSLESIVSTNPIVDTSKVELKGNSDVDINGNVENLFSGKNN
                     GVTISSKNDEISEEKPAVMDIALSEALNMEVVNIKAPEGTAPAKGIVEVTDKDGNVQQ
                     IPYENKEYMKNLKDEEQQEEVNNEQEEVNNKDENINQTDNNSNNKDENNDKQQENSDK
                     QEANSNTNQDKNNDKENSSMDKPNSDEDTPKEEGNISKNNNSTTSTYSKSTLETYADV
                     QNSDIVINLGKQVAVKKITIKITATTANDRNLAEISKVEFLNNVYKEIPKPEMNIPKI
                     NKISTSTAVGNEKVSFYWNNEVNVSAYELILDKIDSKGKVLSTKKLQTSKNTIEVRDI
                     EAYGLYRVSIQSLNGDWSSGYKDATPENLDGVPENVDSNYKPIQFSPDSILEFQVVPD
                     TKPEPPEGINVKGKFKSLDVSWKNHKQAKDFDLYYKEKGSNGSWIKYNDKLIRGTSSK
                     IEGLKDNTTYEVRMTATNHLGTSGMSKTYIGTTESMDAPTTPNYRLINTPKENGGFGI
                     PTNHIVDVTYPAGYDKSEYSDKNPFDKFNVVDGDFTTHWTFPTYNAAEGTNRGPIITF
                     DKSYTMDTFMATPRFDVSDKTINDFEVRYWDENGQLHNLGDVPFETKTDPVNNNKYVM
                     VRLKEPITATKIQVSVCSSYSYKSNISELKFYEYDSIEDDVRNLFMDDLQVELKEDVT
                     QEKITELKDRLNTPDKASGEYHPYKTVIERELKLAQDLYNDRATLTDVTTVNQEINKL
                     GKYKDKNGQYTVNSNNLGMQNDWQALGVAARAGDEITVYVGSKSGKTPKLIYTQYYGE
                     SGAYKSGEINLKTGKNVIQLSKLHSLDIECGGSLYIRYAEDTPSGGDIKVRVAGATKI
                     PHLNLNGTINDKSPAGVSESKKKIKAYIEELAKYKDAVKGEPYYPGTNVGNSYGYSEK
                     TGVLNTTDIESDKVTLNVPATAVYQGISKGNADLNTQVDRLYNSMLAWEQIMDLVYSE
                     RGVFKTQDLDGNGTVDDNEFNLTKNDMAPKSRMNIKYQRMFIGAFMYASGLHVGVEYG
                     SVPGLMNGVPFQIDDSGKATGGNLFGWGIGHEIGHVTDIGKMTYSETSNNVLALLAQT
                     FDDKTHSRLEGSTMDKIYEHVTSNSLGIPSNVFERLGMLWQLHLAYDDDFTGSMLKNN
                     SDVDLSNDTFYAKISRKYRALSSSDPINSLPKDQMLVAMASSVVEKDLRDYFKAWGVE
                     ITPELNSIMDSKNYEKESRKIQYVNDEARRKTLNENIASMAKDTKVSASFSDGIQSGS
                     LVKSNKISIDLDVDKDKDKILGYEIIRSDGNYLEGENGTQVKYRTVGFVDAKGNSKAK
                     FTDNISPLNNRAFTYKVVAYDYHLNPTEEFEVGTVKLSDEGKINKSAWSFITNTVSDG
                     DVRTENDSHGPLQNPEIDNIKDNDASTTYKGKIISKAEWNKDPQKDPDINVEENPYII
                     VDMKETLPIVGLKYTKPKTETRKFSLKGLFNFRKDTSTTYNPLTNYKIQVSNDKKNWE
                     DVSQGTFEYGQDLVGGGKDQDNEARVTFNKDGKLWTYQARYVKLISNNKSNIEVAELD
                     IIGPPGDNIEIGTMNNADQTRTNGIGKLAEDYVYQSDDSNTSEDETGKIPAGSIVITG
                     EYSGNPAFNLPLLIDKNNKTISGEALLFAEVPEKGELGEISKGTWVYYMPKENFDSLS
                     DKVKAELYRYNDLQGDTPVGQRFVSDTMYVPVGAKNYDELKTISLTDSNSKARKATRN
                     AIDVSNKKVVTVSNKVKGNIVRDK"
     gene            61263..63143
                     /locus_tag="KR294_000601"
     CDS             61263..63143
                     /locus_tag="KR294_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp10"
                     /protein_id="HBH0238718.1"
                     /translation="MSKRKSFIRTIAVSTMAVAVTGSATCAYAAPVLQGTKTYEKVNT
                     IDISVDSVENIVYSFQASIKVQGEVEVVDNEQKEKITWSDNIKSQIKSGNANATCRAE
                     YNKSSNTTTLDIYVTSNEDLLDGNRLNIGRISIKKSGSNLNADYKVFGKGTSDKPALK
                     IVTYNNKTVDYENINSDEGLIFTLINESEVKPIGGTGSSKNDPEKYKVEKSEALEYLL
                     NNIRINYSIVSKETQESGLNVILKLGLAQKTTKGRKATINKYVEVTLPKSLEYIVENE
                     LSKPDELPPDNGNGGNNGGGSNSGGSSSGGSSGGGNSSDSTSNVTVKKLKGADRFETA
                     IKISQSGWTKSDTVVIVNGEDKSMVDGLTATPLASVKNSPILLSSNEKLPQKTVEELK
                     RLNPSKVIVIGGNNSMPNSVVEAIKAVNSKISVQRIGGDTRYQTSINIAKEIDKTNNV
                     SKLYIGAGNGEADSLSIASLAGKEKTPIVLTQKDGVDSETEQFIKSNKVSNIYFIGGI
                     EKISNKAIEQVGKIANRDISKNRVAGQTRQETNAKVIDKFYSQSKLDGVVVANQDKLI
                     DALAVGPLAAKNNSPVILATNTLDKSQESSLKGKNSSKLFEVGGGIASSVIDKIKSLI
                     EK"
     gene            63510..65111
                     /locus_tag="KR294_000602"
     CDS             63510..65111
                     /locus_tag="KR294_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp11"
                     /protein_id="HBH0238719.1"
                     /translation="MKMNKKILSLGLAVSLILVNFKSVNASSVVEKIYGKDRYETAAK
                     IADRQTYETVILVNTEKSLADGLSASGLSGATKAPILFTQQNKIPADTNRCLKNIKKA
                     YIIGTEDTISKSVEKELDSKNIQVKRIGGEDRLKTSYLIAKEIATIKKVDKVLLTNAY
                     SGEADAMSVSSVATRDGAPIILTDGKSVPFDVKNIQSYCISSEEIMSNPLVKNTNSVR
                     IEGTDRFETNKNVIDYFFNSADGFYVSDGYQLVDAIAAAPLTKNSPMVLVNDGSDKTV
                     LEGAKNINSVGEMNEKVIQQCINASKSNGQPPTITIGSTEVYKGEKFDTGKLNIVAKD
                     NTGKALPIEVDGFIDTNRVGTYILTLKATDEWGKSTGKRVEIKVLDDKSHDYNSPEFK
                     KMVSTEMYNLINSYRKEKGKEPLVVSSKLEGMANAWSKYMMDKKVFAHYIDGKNAPQV
                     FSEFGMRSEENIAYIYIDSKNVQTTQDAKDLAKAIFEVWKKSPEYNANMLSDEFYSTG
                     FGLYILSDGQVHATQEFLNGNEGIL"
     gene            65330..66928
                     /locus_tag="KR294_000603"
     CDS             65330..66928
                     /locus_tag="KR294_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HBH0238720.1"
                     /translation="MKVNKRVLSIGLTISLIMAGAPNINALSSIEKIQGKDRYETSAL
                     IADKQIYDTVILVNTDNSIVDGLSASGLSGVVKAPIMLVQRDKIPTDVEKRLKDVKNA
                     YVIGTEDTIGKSVENQLKNKGIEVKRIGGEDRIKTSYLIAKEISAIKPVNDGDKVFLV
                     NGYTGEADAMSVSSVAARDGVPVILTDGKSIPFKVDGVQCYSLGSEEIMSNELVSKTN
                     SVRIAGKDRFETNKKVIQRFYKGTKKFYVSQGYKLVDAVAGSPLAKDKPIVLVNDGSD
                     KSVLRGADEVTSLGGMDKKVVDQCISSASDKNTMPTITANDVEISVGDKFDNSMLNIV
                     ATDYYGNNLKPNIEGTVDTSKAGTYVLNISAFDNFGQKCEINVNVKVIINTSTKDPNS
                     YEFKAMVSNEIYNLVNSYRDEKGKKPLKELKSLTGMANAWSKYMYEKEIFAHEINGKN
                     AAEVFSGFGMRSGENIAYLPMNTQSIYGDKEAKEIANSIFDLWKKSSKYNDNLLKSEF
                     YSFGFGMYVSSNSEVHATMEFLNS"
     gene            67163..68995
                     /gene="slpA"
                     /locus_tag="KR294_000604"
     CDS             67163..68995
                     /gene="slpA"
                     /locus_tag="KR294_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-layer protein SlpA"
                     /protein_id="HBH0238721.1"
                     /translation="MKKRNLAMAMAAVTVVGSAAPVFAAASDVISLQDGTNDKYTVSN
                     TKASDLVKDILAAQNLTTGAVILNKDTKVTFYDANEKDSSTPTGDKKVYSEQILTTAN
                     GNEDYVKTTLKNLDAGEYAIIDLTYNNAKTVEIKVVAASEKTVVVSSDAKNSAKDIAE
                     KYVFEDKDLENALKTINASDFSKTDSYYQVVLYPKGKRLQGFSTYRATNYNEGTAYGN
                     TPVILTLKSTSKSNLKTAVEELQKLNASYSNTTTLAGDDRIQTAIEISKEYYNNDGEK
                     QDHSADVKENVKNVVLVGANALVDGLVAAPLAAEKDAPLLLTSKDKLDSSVKSEIKRV
                     LDLKTSTEVTGKTVYIAGGVNSVSKEVVTELESMGLKVERFSGDDRYETSLKIADEIG
                     LDNDKAYVVGGTGLADAMSIASVASTKLDGNGVVDRTNGHATPIVVVDGKADKISDDL
                     DSFLGSADVDIIGGFASVSEKMEEAISDATGKGVTRVKGDDRQDTNSEVIKTYYANDT
                     EIAKAAVLDKDSGASSSDAGVFNFYVAKDGSTKEDQLVDALAVGAVAGYKLAPVVLAT
                     DSLSSDQSVAISKVVGEKYSKDLTQVGQGIANSVINKIKDLLDM"
     gene            69237..71579
                     /gene="secA"
                     /locus_tag="KR294_000605"
     CDS             69237..71579
                     /gene="secA"
                     /locus_tag="KR294_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HBH0238722.1"
                     /translation="MTVLDRIVDKSDELEIKVLNYIVDDIETLEPKMESLSDEELKDM
                     TNIFKDRLKQGETLDDILQEAFAVVREVSKRVLGMRQYRVQLIGGIVLHQGKIAEMRT
                     GEGKTLVGVAPIYLNALLGKGVHVVTVNEYLAQRDKETMQPVYEFLGLSVGVITSDLL
                     PEDRKKQYNCDITYGTNNEFGFDYLRDNMVTRKSEKVQRELYYSIVDEVDSILIDEAR
                     TPLIIAGSGKEDTKLYELANAFIKTLKDKDYEIDKKENTVCLTHTGLSKAESFFGIEN
                     ITNIDNIEIYHHTNQALRAHKLMERDVEYVVKDEEIQIVDEFTGRILDGRRYTDGLHQ
                     AIEAKEGVKIKDESKTLATVTFQNFFRLYEKLSGMTGTAKTEESEFESIYKLNVVQIP
                     TNKPVIRADLQDKVFRTEDAKYNAVVEEVIKINKTKQPVLVGTVSIEKSEMLSKLLKK
                     RGIKHEVLNAKQHDKEAEIISRAGKLGSVTIATNMAGRGTDIALGAGDKIEEKKVRDI
                     GGLYVIGTERHESRRIDNQLRGRSGRQGDPGTSRFFVSLEDEMIKLYGGKGIEKILKR
                     MNAKDEDAIESKSLSKAIERAQRGIEGKNFEQRKNVLKYDDTINEQRKVIYEERNRVL
                     NDLNISEDIQKMVREIIEDAANKYLSNQRDYYGYFKSLYNDFMPPNTLLIPGVDKKSV
                     DEVVQHTYEISKRVYDIKKMEVGIDKIEELEKRVLLQVVDTYWMDHIDAMDQLRQYIG
                     LKSYAQKDPFKEYALEGYDMFEELNRKIRTTTVQYLYKFD"
BASE COUNT        28394 a         8125 c        12558 g        22654 t
ORIGIN      
        1 taaaatatat tgtgaatctg agaaaattac tatttttctt tgagtatttt ttgtaagcag
       61 ttctaaaaga ttcaatttca tacctattac ttgaatcatt catcaaaata attctaattt
      121 aaaaaataat tctatccaaa taatagatat ataggactat gttataatat aaaaaaattt
      181 atataaaagt taataactat acaagattga taaagaaaaa gtcaaaatag ataattgatt
      241 agcaaaatag atataattat aatgaagtta aatctagcaa tattctccta aaattaaatt
      301 tcatttattt aattaaatat aatttgacaa tgggcaaaaa agtgagtaaa atataaataa
      361 aataaaaata acaggttcgg ataaagaaaa aggtttctta acctcaagca taaagtatat
      421 tatctaagtt atttgagatt aagagataaa tccaatctta ggtactgagg aggaaaaaat
      481 gcttgatata aaaagaataa gagaaaattt agattgtata aaaaaagcaa tggaaagaag
      541 gggcgaaaaa aactttaacc ttgatgaagt agttaagtta gatgatgaaa gaagaaagac
      601 tcttcaagaa gttgaagtta tgaaaaatga attaaataca gcatctaaaa atataccaaa
      661 tcttataaaa gaaggtaaag atgtagaaaa tgaaaagatt aaattaaaag agttatctga
      721 taaaattaag gtaatagacc aaaatcttaa agaagtagaa gataagatgg aatacctatt
      781 aatgagaata ccaaatgtac cacatccaga agtaccacaa ggtgaaactg atgaagataa
      841 tgttgaagta agaacttggg gaaagactac tacctttgat tttgaatcta aggctcattg
      901 ggaaattgga acagaattag gtatacttga ttttgaaaca gctagtaaaa taactggttc
      961 aagatttact ctttacaaag gattaggtgc tagattagag agagcattat taaattttta
     1021 cttagacacg aatacaaaag taaatggata tacagaagtt attccaccat ttatggcaaa
     1081 tagaaatagt tttttaggta caggacagtt acctaagttt gaagaagata tgtttaaaat
     1141 agaaggtatg gactatttta tgattccaac atcagaagtt cctttaacta atatacatgc
     1201 taatgaaata cttaaatttg aacaattacc gataaattat acagcttata ctccatgttt
     1261 taggtcagaa gctggttctg ctggaagaga tacaagaggt ttagtaagac agcatcagtt
     1321 taacaaagta gaaatggtta aaatagttgc accagaagaa tcttacaatg agttagaaaa
     1381 gcttactaac aatgcggaaa ctatgctaca attattgaat ctgccttata gagtagtaaa
     1441 gatatgtaca ggtgatttag gatttacggc ttcttttaaa tatgatgtag aagtttggat
     1501 gccaagttac aataggtatg ttgagatttc atcttgttca aactgcgaag atttccaagc
     1561 tagaagagca ggaataagat ttaaaagaga taaagattct aaagctgaat atgtacacac
     1621 attaaatggc tctgggttag ctattggaag aagtgttgca gctatattag aaaattatca
     1681 acaagaagat ggttctgtgg ttgttcctga agttttaaga ccatatatgg gagtttctgt
     1741 tattaaataa gagttaaatt atgtattttt aagtaataca ataatataga ggtaataaaa
     1801 aataattaat ataaaagtga tacaataata tagaagtaat aaaaaaatag ttaatataaa
     1861 agtgatacaa taatatagaa gtaataaaaa atagttaatg taaaagtgat acaataatat
     1921 agaagtaata aaaaaatagt taatataaaa gcgatacaat aataatagaa gtaataaaaa
     1981 aaaataatta atataaaaat gtgtacaaac taatgaatat tgatatagta agctatcata
     2041 tgaaagagta tgtacacatt ttttttacta atttttcaca atatgaacat aaataattta
     2101 caggaaagga atcttttatg aaaattcaaa atactgagtg gggatatatt gaatggaaac
     2161 atacttatga tgaaaataat ccaaaacaag ctatgaatat atacattgca gtaactatgc
     2221 ctggtaagaa acattttaat catgttcatt atggtcaaga gcagatgata tatattttag
     2281 agggagaggg tttgtatatt ataaatggag tttggaagcc attttatcaa ggtatgattt
     2341 tttatataga atctggtagc acacatgaaa ctataaatac aggcgataga gaaataaaag
     2401 aacttattgt ttcaaataat gtagatgatg taggagagag tgaagttata gatattaatc
     2461 ctaataatta tttaaagaag accttgataa attatagtga aagtacatta aatttgtatg
     2521 cagcagtaga atcaattcgt ggtcaattta tagacccgtt taaaattcca ttaattatat
     2581 atgatgattc atggaatata gttttaaaaa atccttattt tccacttttt tgttttgaaa
     2641 aatgtaatcc tatgaaattt cctcaaaatt gtgattgtat gaatcaaaaa agtagcaatc
     2701 aatttgtatg tgaatatggg ataactatat ataatatacc aatactgtac aaaagcaata
     2761 gcataggtgt tataagagga gggtatgtac tattatctga tttgaattta gatacagagc
     2821 ataataattt atatgatatt ccagagggag ctgctagaag tataaaacgc ctcttgaaac
     2881 aaatatctaa aaatataata aatttttgct cttttaatga tataagaaag gatttacaag
     2941 aaaaagagaa gactatagca agaacatatc attatggaga gcaacttgaa atgaatttaa
     3001 aagtagctca agatatggtt actaatttaa gaataaatca tcacttttta tttaatacat
     3061 taaattcaat ggcaagcata gcactagatg atggtagtta tgatttgtat agtgcaataa
     3121 tagatttatc aagaatgttt agatatacaa tgaggtctga tttaagattt gtagaattag
     3181 aatctgaaat attatacatt aaaaattatt tgaatttaca gaaattacgt tatggagatg
     3241 cacttaaagt aaaatatctt attccagaga agttatataa cctttctgtg ccttttaact
     3301 ttattcaacc tattgtagag aatgcattta cacatggatt tagagatatt gacacagaaa
     3361 agcgaattga aataattgca agattagatt ctcagtatgc cattatagag attcataata
     3421 atggaactat cttagatgga aataatatag acaaaataaa ggcaggtatt cgtagtaata
     3481 atggtcatgg tttgtcttta atatatacaa aattcacatc tgcttatgga aataattttg
     3541 atatggatat aaagtcgagt gataatgaag gaacttacat aatgattaaa attcctattg
     3601 aaaattataa ggagtatgta tagaacttgt gaaaaattaa taagttttat aaatgttaag
     3661 aaatatatta gatgttttta tgttgtttta tatatcttac ttttttatat tattaagcta
     3721 aaagggaggt attctcatga gaagagcact aataatagat gatgaagaag ctgttctaaa
     3781 aataataaca cattttatag aaatgaaaga tatgccaata aaaattgttg gtaaagcaac
     3841 atctggtgat gaagcagtag ataaaatcat tggtttagag ccagacatag tttttataga
     3901 tattcaaatg ccaatataca acgggttaga agtaatagaa aaaacatctc atttatctaa
     3961 aaaaataaac tttgtagtaa taactgcatt taactatttt gaatatgctc aaaaagcttt
     4021 gagattaaat gtaaaagata tactccttaa accattggat atgaaagaat ttactaagtc
     4081 tgtagaaaaa attattggat atcaatatac caataatgat ttattaaatg agatactgga
     4141 atatataaat ctaaactata gcaatgactt aaagttaaat gattgtgcta gattattttt
     4201 aaccaatcca tctaatatat ctaggatttt taaaagtaat ttaaatacaa cttttatatc
     4261 atatctaaat catataagaa tagaaaaatc tattgagtta cttgaaaata ctacaaaaag
     4321 tataaatgag attgcagaaa tagttggata taatagccta aataactttt ataaaaactt
     4381 taagatagaa aaaggaatga ctccaaaagt ttataaactg aacactaaaa attgaaattg
     4441 ataaataaaa agtcaatata gataattgtt tgagtgtgtc tgaataagta tactttaatt
     4501 atgataaaaa ttaaagcgct ttaaacatat ttaataatat taaaccttat aaaagctgta
     4561 cctatttata taaaaaaata tatataaata aaaagaaaaa gatatacaaa ataaaaaaag
     4621 tgaattaaat actgtttcaa aaagacagaa ttttcattta atttactgag agtttatatt
     4681 tcttaaagga aggtaacttt ataatggagg taatttaata tgtcagacaa agtgaatatg
     4741 aaaaatatta tctgtattgc aggcgcttat ctagcaacag caattggttc tgggtttgct
     4801 actggtcaag aaattctaca attttttgcc tcacaagggt atatgggttt aattggagca
     4861 ttaatatcaa tggtattgtt ttcatttctt ggtgctgaag ttataactag aggtagagaa
     4921 ttaaaactta aagaaccaac aagaatttac actttttatt gtgggaagat tttaggaaaa
     4981 ttttacgaat ggtttagtcc aatattttta tttgggattc ttatagtaat gatttcaggt
     5041 gcaggctcaa ctttaactga atactatggt ataaatcctt acttaggaag agtattgatg
     5101 gctgttgcta ctttaattac agtgtctatg ggtttagaaa aattagtaag catacttgga
     5161 cgtattggac cagtgatagc agtatttaca attgctgttg gattaataag cttgtttaag
     5221 cattttgacg gtttatctat ggttggagaa gctatgaaaa atattgaagt tacaaaagca
     5281 tcagaaagtc caatcgtttc tggtgtaata tataatacat taaatattat tgtaatgatt
     5341 gtttttttaa caggaatggg agcttctatt gaaagtaaaa aggatgcttt ttggggaggt
     5401 ttattaggtg gaatagtgtt tatgactgct ggtatagtta tgtatttggc tatgatttca
     5461 gatataggaa atttgtatat gaaagaaata ccatcacttt atttagcaga taatatatct
     5521 ccgattgtag gtgtatgttt ttcagttgca ttaatattag gtatctatac aacagctgtt
     5581 ccacttttat ggtctgtaac caatagaatt gttgaagatg aacatcctaa atttaaattg
     5641 gtaacaacag taatagctat tttggcttgt ataggaggtt ttttaccgtt tggtaaatta
     5701 gtaaacattt tatatccata tacaggttat atggggcttt taattttagt ctgtatggtg
     5761 tataaagcaa ttacatgtag aaaaaaatca acacaaagtc aggaatagag ccacttatta
     5821 atagttttta tttaaaaaaa ttttttatat aatccgaatt taaaaagtca aaatagttaa
     5881 ataaattgca aaacatgata atatatttaa ttaaaataat atagtaaaat ataaatataa
     5941 actaaaatta aatttataaa aaatatcttt ataaagatta ttaacttata taatttgtag
     6001 ttaaattata aaaaataaaa aaataaaatt ttggagaggt gttagtatgc atgaacttat
     6061 tttaatctca gaaaagtata aagaagatat tttagatttt tttacagata ttcatatgca
     6121 ccccgaatta agttttaaag aatttaggac tacaaaagct ataaaagatt tattagtgag
     6181 tttagacata gaaatattag atttaggaat ggaaacaggc gttgttggat tattaaaagg
     6241 gaagtatgat ggtcccacag tagcactaag aggagatatt gatgcgttgc caatatatga
     6301 agaggttgat attaagtata aatccagata tgatggtata atgcatgcat gtgggcatga
     6361 tatacacacg tcttgccttg taggatgtgc atatgtattg tctcatatta gagatagtct
     6421 tcatggaaat gtaaagttta tatttcaacc agccgaagaa gtcaataaag gtgcgaagat
     6481 gttagtggaa cgaggagtaa tggaaaatcc aaaagttgat gctatatttg gacttcataa
     6541 tcatccagat ataccttgtg gaaaaatagg tgttaagtta ggtgggttaa tggcagcagt
     6601 agacactatt aagatagaag taaatggatt tggaggtcac ggaggtatac caaacagaac
     6661 aatagaccct atagtagcat caagtgcaat tataatgggt attcaaacca tagtaagcag
     6721 aaacataagt ccattagaat cagctgttat atcaataggt actataaatg gagggactgc
     6781 aaataatgta atttcagaaa aggtagatat gacaggcaca tgtagaagct ttagtaatga
     6841 agtacgaaag aaaatatcag aaaatttaga aaatatagtt tgtgagatag ctcgtggata
     6901 tcaagcaact gcaaagctag attatttatt tgatttacca gctgttataa atagtaaaga
     6961 gatgtacgca atagcttgta agtctgtgtg tgatttgtat tcagaagatg ctatagttga
     7021 tccaatacct tctacaggag gggaagattt ttctatattc atggaaaaag ccccaggatt
     7081 tttttactgg ttaggggtag gcaacaaaga acaagattgt atatatcagt ggcataatcc
     7141 taaatttaaa gctgataaaa attctatatt ggtaggtaca aatgtactat gtcagtctgt
     7201 tataaattat atggataaat taaaaaataa aatttaagat agagcattct ggagataaag
     7261 tttatgaggg ggtattagtt tgaggaaaat taattcacag gaaaaaaaca aagatagtgg
     7321 attattgatg agggcactaa atgttgtaga gagagcagga aataaacttc cagacccagt
     7381 aaccatattt ttattactat gtataattgt tgtaatattg tcagcagtta tatctaattt
     7441 aggagtagaa gaaatacatc cttctacaaa agaagttgta aaggtagtaa atctactaga
     7501 gaaagagcag attcaatcat atttaggtag catagttaca aactttcagt catttgctcc
     7561 tttaggatta gtactggtta caatgcttgg agcaggtgtt gctgagaaat ctggatttat
     7621 ggaagtgtta atgaaaaagg gtataagtaa agttccacaa aaacttgtaa ctgtagcaat
     7681 cgtatttgca ggtatgttgt cacatacagc agcagatgta ggatttataa tattaccacc
     7741 acttgcagca cttgtgtttt taggaattgg aagacatcct cttgtaggta tgtttgcagc
     7801 ttttgcaggt gttgcagggg gatttgcagc aaatgttatg cttagtacta cagatgtatt
     7861 gttagctgga tttacaatac cagcagctca aatgatggac ccatcttacc aaggcaatcc
     7921 agcaatgaat ctttattttg cttttatatc agcgatagtt ttaacttttg caggagcatt
     7981 tgtaactgaa aaatttatag ctcctcgttt tacaaaatat aatgattcaa caaatgataa
     8041 ggatatacag gaattgagtg aacttgaaaa taagggtata aaatacgctt tattatcatt
     8101 gttagttgta gtagtagtga tagttgcctt atgtataggt gacaatgcat ttatgaaaga
     8161 tccagagact ggttctatac tatctagtaa tgcaccttta atgaaaggta tagttcctat
     8221 aatcactatt atatttttaa ctccaggatt agtgtatgga aaagtaagta agaagataaa
     8281 aagtgacaaa gatttagtat ctatgatggg tagtagtatg agtgatatgg gtggatatat
     8341 agtcctagca tttatagcat cccagtttat taatttattt aatcttagta acttaggaac
     8401 aattttatca ataacaggag caaaattact agcagagtcg ggaataccta gctatggatt
     8461 gataatagga tttatattgc tatctggatt tatcaattta tttgtaggaa gtgcttctgc
     8521 aaaatgggcg attttagcac ctatatttgt tcccatgttt atgctactag actttaatcc
     8581 agcattaact caaatagctt atcgtattgg agatgcttca acaaatccaa taagtccact
     8641 ttttccgtat tttccagtta tattggcctt tgccagaaga tatgataaag atataggtat
     8701 aggtactgtc atatcgaata tgattccata ctcagtggta tttacattaa tagaaataat
     8761 aatattgtta ctattcatgg gtattggcat accattagga cctggtggag gaatatctta
     8821 cgttttatag accgttataa taaatttatc aatgaagatt aaactaataa aatatattct
     8881 ttaattaaga ggaggattat tatgttaaaa acaacaaaaa tttcagaccc agagttatac
     8941 aagattgtag ctgatgagtt ggttagacaa gaacacaata ttgagatgat agcttctgaa
     9001 agtacagcac caacagaagt acttgaatta agtggatgtg tatttacaaa taaaacagaa
     9061 gaaggctatc caggggctcg ttttcaagca ggttctgaag aagcagataa acttgaaacc
     9121 ctagcaataa aacgtgcaaa agaagtattt ggagcagaac atgtaaacgt acaaccgtat
     9181 tcaggttcta cagctaacta ttgtgtatat tcatcaatat taaaaccaaa tgacactgtt
     9241 ttaagtatgc gtcttgacca aggtggacac ttgacacatg gtagcgcagt taatttttta
     9301 catgacattt ataaatatga attttatggg gtagacccaa atactggacg tatagattat
     9361 gatgctcttg aagcaaaggc aaaagaatgt agaccaaaac ttataattgc aggggcaagt
     9421 tcatatccaa gattaataga ttatgaaaga atatcaaagg ttgcaaaaga agtaggagct
     9481 tactttatgg tagatatggc acatgttgca ggattagtcg cagcgaaagt aatacctagt
     9541 cctgtacctt atgcagattt tgtttcttca tctacgacaa agactttctg tggaccaaga
     9601 agtggtattg tactttgtaa agcagaacat gcaaagaaac tcgataaagg tgtttttcca
     9661 ggaacattag ggtctataca tcttaataca gttgcagcaa aagccttttc actattatat
     9721 ttaagtacag ataaatttaa aaagataatg gagcaagttg tagtaaatgc tcagactcta
     9781 gcttctgaac tgatttcaca tggttttagt attgtaagtg gaggtactga taatcatata
     9841 gtaatggttg acttaagaag taagaatctt acaggaaaac aatttgaaaa agctcttgaa
     9901 tatgtaggaa taacagttaa taaaaatgtt atacctgacg acccacaatc accatttgta
     9961 actagtggtg ttcgtatagg tcttacatca atatctcaaa gaggtctgaa agaaaaagaa
    10021 gttatacaga tagcagggat aatgaataag gtagcagaaa atattgataa taaagaagta
    10081 ttagatgaat gtaaagcaga ggcacaagaa cttatatcta agtttccatt atatccagaa
    10141 gggtattttg aagattaaat attttgattt gtatagctca caatttataa agcctgtaac
    10201 ataaaattta ataatatata accactataa ggtgttgatt aatcaacacc ttattttttt
    10261 tgaaaagtaa tatacaagct atcataagca tataattcct tatagataat taacaagggg
    10321 gataaagtta tgaggtatta taataaacct accaaagaag tattaaaata cttaaaaaca
    10381 aatccagaaa ttggacttga tgataatgag gtagaagaaa ggaagcttag atatggatta
    10441 aatgaattta ctataaaaga aggtagaaca ttttgggacg agttgggaga aagtttgaca
    10501 gaacctatga tattaattct cataggagca gcagtaataa gttcttttgt gggagaatta
    10561 catgacgcat taggtatttt aggggctatt tttattggaa tttctatagg cataataact
    10621 gaaggaaaat ctaaaaaagc agctcatgcc ctgtcaaaat taacagaaaa tatagaagta
    10681 aaggtgctta gaaatgggaa gataattaaa atatcaaaaa atgatttagt accaggagat
    10741 attgtatata tagaaactgg ggatatgata ccagcagatg gaagacttat acagtctata
    10801 aatttgaaac ttagagaaga tatgctaaca ggagaatctg atgatgtagc taagaatgct
    10861 gatgctgtat tagatatgga agtagtttat tctaaaacag aaataatcga acaggatgca
    10921 atacctgcaa agcaagtcaa tatggtattt ggagggactc ttgtagcata tggtaggggc
    10981 ataatggttg tcactcatac tggtgataag acagagatgg gtaagatagc acagaattta
    11041 tcaaatgaag accagcaaac tccacttcaa attaaattag ggaagttggg tgctaaaata
    11101 gcgggaatat caggcgtaat agctacttta ttatgtatgt ttatgattat acagatgcag
    11161 agaaaaggta tgttaatttt agatacaagc agtgtattat ctttcttaca atcattagaa
    11221 cctgctaaaa atgcatatat ggtttgtatt gcattaatag ttgcaactgt tccagaaggt
    11281 ttgccaacta tgataaatat taccttagct ataacaatgc aaaagatggc aaagataaat
    11341 gcattagtaa caaagaaaga agcctgtgaa actataggtt ctgtttctgt aatatgttcc
    11401 gacaaaacag ggactttaac acaaaacaaa atgatggtag aggtagcata tgttgatggt
    11461 aaatatataa gtggaggaga gtatcaaagt aatagctatt ttgaacaaaa ctgtatagta
    11521 aattcaactg cagatataga aaaagaagat aattcattta aatatatagg aagcgcaaca
    11581 gagtgtgcat tacttttata tcataatgat aagaactata atgaaatgag aaaacaaacg
    11641 tatttgatat cacaaatacc atttagctca gaagaaaaga agatgtcaac attaattcgt
    11701 caagaggatt cagatatatt actttcaaaa ggtgctccag aagtattatt aaaaaaatgt
    11761 tcttatgtac aacaaggaaa aaatattgtt ccaataactc caaaagtaga aaaaagtatt
    11821 ttagatgaga ttaagaagtt acaaattaaa tctatgagaa cattaggatt tgcttataaa
    11881 aaaatgagta attctaaaac agaagttgca atgacttcag aaggtgaatt gaatttaata
    11941 ggaaattcaa gaagttatat gaaggaagat aatttagttt ttagtggatt tgtaggaata
    12001 gtggacccat tgagagaagg ggtcaaagat tccattgata aagcatttaa tgcaggagta
    12061 gatgtaaaaa tgcttacagg agataatata aatacagcaa cagctattgg aaatgaatta
    12121 ggattattaa atgatgggaa aaaggcagtt gaagcaacat atatagatgt attgacagat
    12181 aaagaattga gagaagaaat caaaggaata tctattgttg caagaagtaa accagataca
    12241 aaaatgagaa tagtttcagc acttcaaaaa agtggcgaag ttgtagctgt aacaggtgat
    12301 ggtataaatg atgccccagc acttagtcaa gcagatgttg gaattgcaat gggtatttca
    12361 ggaacagaag tatctaaaaa tgcagcagat ataatattga ctgatgatag ctttagtact
    12421 atagtagagg gaataaaatg gggaagaggt atatatgaga actttcaaag atttatacag
    12481 tttcagctta ctgtaaatat agtagcattt ataattgcta taatatctca acttactggt
    12541 aaggatatgc catttactac aatacaatta ttatgggtaa atataataat ggatggtcct
    12601 ccagccctag cattaggatt agaacctgtt agagattatg tattgaaaag aaaaccaata
    12661 aatagacatt ctggaataat agctaggtct atgtttgtaa atattattat aaatgctatt
    12721 cttataatta caattgtatt tactcaatca gcttttaata tattgggagc tacatcagaa
    12781 gaacaaggta ctgttatatt ttctttattt gcattcagtg ccctttttaa tgcattaaat
    12841 tgtagagagt ttggtttaaa tagtacaata ccaaatttct ttaaaaataa actggcattg
    12901 caaataatag tagttacagg gataattcaa ataatattta cacaagtgtt ccagagtttc
    12961 tttaattctg tttctttgga ctttgatatg tggataaaga taatactatt tgcatccact
    13021 atcctattgt caaatgaatt tgtaaagcta attcttagaa caatgaaaaa tagtagaact
    13081 atgaacttta atagtaaaaa ttaattccta tgaaaccgca aagtactata tattgtaact
    13141 ttgcggtttt tgtttgttta atgttgtttt atattaccat tttcatattt aattttttat
    13201 taatctaaac acaatcttcc attgtaattg cttcatctgt gtcaacacat tcaaagtcaa
    13261 tatctaattt ttgtaatatt ttgtatgcct ctttttgcaa aggagtatca aattcaatag
    13321 gtgattttgt gtaaatataa ctgataaaaa acatgattta tttcattcct ttccatttaa
    13381 aaacttatag ttatagtgta tcataaggtt ataaaatata gataaatata gtataaattt
    13441 aaaatatgta cagacaaaac aaaaaaatca tattctaagt aatacttggg aaaaatgata
    13501 ttatcataat aaataatctt tgtaaaaact tatatagaat ctattaaaca gacactaagc
    13561 cataaaaact ttactaaata taaaattcgt atctaaatag atatatagaa taatatttta
    13621 ctgaagtaga gtgattttta agaattttat atataaatta tgttatcata aataaagata
    13681 tagattataa aatttgttaa taaaataaag ggcagggagg taagtttcat gttttccaaa
    13741 atcctagtca aaacatttat cagagatagc gaaaacgttc aaaatacaga tgttagaaat
    13801 aagtatggtt atgtagctgg tgtagtaggt atattatcca atttactttt atttgtgata
    13861 aaggtattca taggaatgct cacatctagt atagctataa tggctgatgc atttaataat
    13921 ctttctgata tggcatcttc agcaataact atgataggtt ttaaattagc aagtaagcca
    13981 gctgataaag aacacccttt tggtcatgga agaatagagt atttatcagc attaatagta
    14041 gcatttatgg tgatgttggt tggacttcaa tttgtaaagt catctataga aaggatagta
    14101 aatccaattc ctgtaaaatt tgaagtaata ccacttatac ttttaattgc atctataatg
    14161 attaaaatct ggttgagtcg ttttaataaa tttatgggaa ataaaattga ttcttcagcc
    14221 ttaaaagcag tttcacttga tgctttagga gatgtattta cttcaagctg tgtagttata
    14281 tcatttattg tagctagatt tactaatttt cctatagatg gatatgttgg tatcgtagta
    14341 tcattagtga tactttatgc tggtttctct cttgtaaaag atactataaa tcctctttta
    14401 ggggaagcac cagatgaaga aatggtaaat tctattatag agctattgtt atcttataaa
    14461 tatataatag gtacacatga tttaattatt cataactatg gagttggtag atgtattgca
    14521 tctatacatg cagaaattcc atccaacata gatataatgg aaatacatga aattatagat
    14581 actgcagaga gagaaatatc tgaaaaatta gatatatatc tagtaattca catggaccca
    14641 atatgtcttg aagataaaga agttatgtca gccaaaaaag aacttgaaga aatacttaag
    14701 aaaaatagtc ttgtaaaatc tatgcatgat tttagaatag ttggaaaagg aagcaagaag
    14761 aatttaatat ttgatatagt agttaatcct tccgaatttt ccaaaaacat gtcagaagat
    14821 gacttaaaag aagatataac aaaattagtt aaggagataa atcctgaata taattgtgta
    14881 attgttgtag ataaggattt tatttaatta ttaattaatc tcatcataag gtaaaaaatg
    14941 taaaaaggat agacaatagt atagaggcat aatataatag aagtatataa ttgtattttt
    15001 aatataaata aagcaatttt aattgttttt atgaaatatt atagagatgt tgaagtatat
    15061 tctattattg ggcaccttat ggatatactg agtcagtggt gcaaccggct atgaatataa
    15121 atttatttat tttcatagct ttttttgtat aattttttag taaaaattac tttatatacg
    15181 atattaatgg aagattagat tataaattat aggtaaccta aaggggtgag atttacatga
    15241 agaaaggaaa tagaaaggca ttattaatta gtttaattat gattttaagt atggtggtgt
    15301 ctacaatata tccaactgta tcttatgctt cagaattagg agagaatagt cagattcaaa
    15361 gtggttcaac taattcatca actggagagg agaaggaaag cgacaataaa aagccagaac
    15421 agactccaga gaaagataag gcaacagata ataaaaaacc agaacagacc ccagaggaag
    15481 aaaaaccaac agataataaa aaaccagaac agaccccaga agaagataag tcaacagata
    15541 ataaaaagcc agagcaaact ccagaaggag aaaagccaat agataataaa aagccagagc
    15601 agataccaga agaagataag tcaacagata ataaaaagtc agaacaagct ttagaagatg
    15661 aaaaaccact agacaataaa aatacagaaa aaactccaga ggaagataat ctattagaag
    15721 atgaaaattt attgaaagtt ttagaagaag aacttaatga agaaaatgaa gactatggat
    15781 ttgttgtaaa aattaataac aatacaatag aaacggaatc aatgaaaaaa atatcattta
    15841 atttaactta tactccaaca tcaaaaggaa tacaagcagg agattcaata acttttaagg
    15901 tgccagatgt attcaataaa gttaatttag attatacaag tgaatgcttt gataaaacag
    15961 aaagtaatgg agagtataca cttacattta gagaattacc taatggccaa agtgtaatgc
    16021 aaggtaaaat aggtttggaa gcatatgtta aaaaggttga tgaagatact aatgcaaaaa
    16081 tacatattga aactactgga aaaatagaaa gtggaagtgg agatatagat gtagaaataa
    16141 aacctggaga taaaacggat gttccagatg ctaaaggaac acttaaaaag cttgttgaag
    16201 gaaaaaaatc aactactgta tttatgccag ttaaaaataa agatataaat tacagtatac
    16261 aagtaaatga aaagcaggaa gagttaaaag atattatttt gtatgatgag cttcctgaag
    16321 gattgacatt gataaatggt tctgtaagtg tagtaacaag tgatggaaaa gaagttagtg
    16381 attttaatat tgaacagagt aaaaattcta tttcagttaa ttttggaaat atagataaat
    16441 cgtatactgt taagtataag gctagaatca gtgacaaaaa cgcaaaacat ggtaataaat
    16501 ataagaatgt agctaggatt gaatctgatg gtaagaagat acaagaagat gatgctactg
    16561 taagtatatt tgatagagga gatgattatc ttcttactaa aggacattca ggagcaacaa
    16621 atattactca agttggtcaa gtaataaact atcagatttc aataaatgat gataaatcac
    16681 caataagtaa tgttgttata acagataata taccagaagg catgagatta actacttcag
    16741 gagaagctgg gcatgatttt agagttgtag aaattccaat gaatgggagc tggactcctt
    16801 ggagtaaaga aaaaattgcc aataatattt catataaagt agaagaaaaa agaaatgaaa
    16861 gtgggcaagt agataaagtt ataactggat ttacaattaa tctcagtaaa gaagaagtgg
    16921 aatcaaagtt ttttatagct tatacattaa aggtaattag tattgaagat agctatataa
    16981 atagagctgt tcttgatgca aataatagtg aaattgataa aaatgatgag ataaacttta
    17041 agaaaaattc tggattaata agcgcaaaaa aagaagttga taaaaaagtt ttaaatagta
    17101 gtgataacca gattgttaaa tacaaaatca atatgtcaac ttatggagtt tatgatgcag
    17161 gacaagtaaa tcttttagat gaagtaaact cagctctaga aatatctaat ataaaatatt
    17221 ctgataatct tgaacttaaa aaagaagctg gagatggaaa aaatacaata agattagtaa
    17281 ataaatacga atttaaacag ataaaagaag gggaacctgt gcaaagttgg gttacatttg
    17341 atgcagactt cacaaatgta aaagttgggg agactataca aaatgtggct cagattaatg
    17401 gttcaagtcc tccaggagta gagactacta agcaaggtta tgcttttgaa gctaaaaaag
    17461 tggatgcttt agataaaaat gtactttcag gtgctaagtt caatttagaa gatgcatttg
    17521 gaaatatagt agttaaggat ttagttagtg atgaagatgg tataattcaa tctagtataa
    17581 aaaaaccagg aacatattat ttagtggaga taatggctcc aagtggatat gaaaaactga
    17641 aggataaaat taaggttgaa attggtaata aagatattgg tagaatagtg gatattggaa
    17701 atatagaaaa cataagacaa gaaaatccac cagtaaatcc accagcacca ccaaatacag
    17761 atgaaccaat agtaaatcca ccagtaccac caagcacaga taaaccaagg aaaccatcaa
    17821 gttcatctga tacagaggat actatagtta taaatccacc aataccacca tcagaagata
    17881 taataaatcc gccaatacca gaggtattga atccgccagt accaccatca gaagagatga
    17941 tagaaactcc tgttaaacag attattccaa taccagaagt agtaaagcca tcagtgtcag
    18001 aagaaaaaaa taataaagtt aaagatgata ctttggtaaa tccaccagta ccaccaaaaa
    18061 caggggatag tactacaatt attggagaaa tacttttggt tataggagct attgtaggac
    18121 ttatcgtatt aagaagaaat aaaaatacaa attagaccct aacattataa aaaatataag
    18181 ttatattaaa aaatatcttc taaaacaata tttaataatg aaaatattgt tagaagatat
    18241 ttttttttga agatttatgt aaaaaaataa taacttttta gaaaaaagtt ccaaagggat
    18301 atagacaatt aaaaagatat aagctataat atagatataa aattaaatga ggcaaaacta
    18361 gggaaaccta gtcacgcaaa gctatagggg ctaaagttta gtaaaccatg ccagccagtt
    18421 gccgaaaaga gtaaaaattt ctttttgtat atacaaagat actcttgggt atctttttta
    18481 ttttgaaatt tattactccc ggcctaactc aaaggaggga ataatatgag accaagtaaa
    18541 aaattattaa tagctataat atcaatattc ttaataagtt cagttccagt aagtgcacat
    18601 gcagatagta ctactataca acaaaataaa gacacactta gtcaaatagt agtttttcca
    18661 actggaaatt acgataaaaa cgaagctaat gctatggtaa atagattagc taatatagat
    18721 ggaaagtatt taaatgcatt aaagcaaaat aacttaaaaa taaaattatt aagtggaaag
    18781 ttaacagatg aaaaagaata tgcttattta aaaggtgtag ttcctaaggg atgggaaggt
    18841 actggaaaaa cttgggatga tgttccaggt ttaggtggaa gtacagtagc tcttagaata
    18901 ggatttagta acaaaggtaa agggcatgat gcaataaatt tagaattaca tgaaacagca
    18961 catgcaatag accatatagt attaaatgat atatctaaat cagcacaatt caaacaaata
    19021 tttgctaaag aaggtcgttc tttaggtaat gtaaactact taggtgtata tgcagaagaa
    19081 ttttttgcag aatcatttgc atattactat ttaaatcaag atacaaatag taagttaaaa
    19141 tcagcttgtc cacaaactta tagctttttg caaaatttag ctaaatagag ttttaataaa
    19201 tttaaaataa atataaataa agagatgcta ttataatagc atctctttta tattgcgttt
    19261 aaatctaata aattttgtct tatgtataac tatgatagat tatcaattac tactccttat
    19321 acaaggcttc aacgtgttta ttatgcattt gagtaattat cgtaggtata atagaaatta
    19381 ttgaaccaat tactatcaat aaaattccta taaccatgtt tatagggata atttctttaa
    19441 gtattaataa tgctagtatt ggagatatta ctggtttaaa gaagaatact aaagatgtaa
    19501 gactagtaga tgtagcttcc attgccataa agtaaagcgc ataaccaaca cctgtaacaa
    19561 atacgaatac ataaatcata atgggcatat tgtgtaaggt atatccacta aaaataggga
    19621 tatttgcaaa tacatgaagc ttatttttat ttaatatatc tgcgataaaa ttaattttag
    19681 tgagtaaaac caatatcaac atttccaaac taccaaatat aaagctaaag caggttacaa
    19741 ctattccacc aaattttaag gtttttcttt taccaaatac agtatacatt gaaaaaataa
    19801 tagcagaaga taatgttaag aatattccac taagagttag ttttgtatgc aatggattta
    19861 ttataactat aattccaaga acttctaata taagtgaaat tacattgtgc ctatatattt
    19921 tttccttcaa aattaagtaa gctaaaagca ttacaaagac tggattacaa ctgaacaaaa
    19981 cagcaactac agatgccttt gtgtttagaa cagcaagttg atacaatgac atacttacta
    20041 ctacacacat aaaacctaaa aatgcaaagt attttaagtc tgattttgta atagaaagac
    20101 taagagctct taatcttttt acagcaaaag gtagtaagac taaaccgcca acaaaaaatc
    20161 ttgataaagt tatttgtaag ggattaaagt cattagtgac agtttttaga ctaatttcca
    20221 ttgaactaaa aaataaggta gtcagtatta tataaacata accttttttc aagtcaaaca
    20281 cctccttgta atttatatta gtactataga taagaatatt caagcatatt ggaataatat
    20341 ggtatgtata aaatatagta cataaaatta taaactacct taatatagaa tgtaagtatt
    20401 ctatactaag gtagttaatt atttgaatta ctttgattta gttattttaa attatataat
    20461 ttggctaatt tttcaaatgc tggtaaagaa cttttaactt tatcataaga tacacaatat
    20521 gatactctaa aatgacctgg acaaccaaaa gaagaacctg gtactaataa taaattaaat
    20581 tgttttgcat cattgcagaa ttttttatca tcttcaattg gagcttttgg gaacaaatag
    20641 aatgtaccat taggtttaac acaagaatat cccatatcga ttaaactatt atatagaagg
    20701 tcaaaattct ttttataaat atttacatca acttctgcat ctaaacttct tgcaataacc
    20761 ctttgaaaaa gagaaggagc atttacaaat ccaagtattc tatttgcaac atttaatgaa
    20821 gacataacat catcaaaatc atccatttgc ccattagcaa caatatatcc tatacgttca
    20881 ccaggtagag ataatgattt actataagag tatcctataa atgaatttct atagtatttt
    20941 agtacacaag gaactttggc accatcataa attatttctc tatatggctc atcagaaatt
    21001 aggtatatgc ttgtattaaa ttctttttgt tttgaatcca ataattctcc aagatttttt
    21061 aataattctt cagaatatat gacaccagta ggattatttg gagtgtttat tattaaagct
    21121 cttgtttttg gagtaatagc attttttaga gcatctaaat ctggctcaaa agtctctata
    21181 tttgtaggaa cttctattaa ttttccatca tagttttctg tataattttt atactcacca
    21241 aaatacggtg caaaagcaat aacttcatca ccaggattta aaagagtttt taaaataata
    21301 tttagaccac cagcagcacc acaagtcata attaaatttt ctcttgtaag atttaatcca
    21361 tcttttttat ttatgtgttc agcaatagca tctcttacat cctcatatcc tgagttgttc
    21421 atatatccat gaactaaatt tggagattct tcatttaaaa tatcatttat aactgcttta
    21481 atagtctctg gaggttcaac acttggattt cctatactaa aatcaaaaac attttcctca
    21541 ccataaatat cagaaagttt ctttccttct tcaaacatag ctcttataac agaactattt
    21601 gcaactaaag tttgcatttt attagatatc atatgtaaca ctccttttta tagatttata
    21661 ttgcttatgt atatattacc atatttttac tgaatttaga caattttcga aaaattactt
    21721 gtttgaaaat ataaactttt atataaaata tatttatgta cagtacatat taaaaattcc
    21781 aatttctaat tttatcatga ttattttata taatagtttt ttaaagaatt aataaaacat
    21841 agatttagag aataaaatat tcttgactat attaattgtt taatataata tagttgatat
    21901 agtcaaacat attataatta tagaagggaa atttaagatg gattttaaaa atttacagta
    21961 tgaaagtttg tcatatatta tttgtaactt gcaaaaaaac tttaaacttt attgtgaaaa
    22021 atgtttaaaa ccatataaac ttacgaatgg tctatatttc tatttaattt atattaataa
    22081 aaataggaat tgttctttga atgatgtttc tacagaattt gaagttgata aagctcatac
    22141 aacaagaact atatctaggt tagaacaaga tggatacata gaaaaaatcc aaaaccctaa
    22201 tgatagtaga gcttttcagt tgagagtaac agataagggt gaggaagtat taggggatat
    22261 aaaaaacata ttttcaaagt gggataatca cataaaaaaa gagttctcgg atacagaata
    22321 taaggaactg gtaaagaatt tacatgtggt aaaggatata aaaacagctg tggaggaaga
    22381 ataggatgta ttgtaattta ttaaaaccaa ttaaaattgg aaatttggaa ttaaaaaata
    22441 gagtatcttt tgcacctaca agcatgggtc ttaaattgga agaaaaaatt aaaaagtttt
    22501 ctgatattgc taagtcagga gtagctctga ttactctagg agatgtatct attagaccta
    22561 gttttcataa ggtagctata agcctatcgg atgaagatgg agtcatgaaa tacaagaaaa
    22621 ttgtagatga aatacacaat tctggtgcaa aggtatcagc acaactattt tgttcagatt
    22681 atgatgttaa tttaattaaa gatactatga atatgggaat tacttcacat gatgagataa
    22741 aaaaaataat gaatgacgga gtaaaagatt acataacaaa tatgcccaaa gaagaaatta
    22801 aaaatattat aaatttattt aaagtaacag cattgaatgc aaaaaaagca ggttttgaca
    22861 tgattcaaat tcatggtgat aggcttgtag gaagtttttc atcaagtata tttaataata
    22921 gaaatgatga atatggtaga acgtgtgata atagaagtag atttgcaagc gaaataatta
    22981 gtagtatccg agatgaagtt aaggacattc caatagacta taaatttgca ataagacaag
    23041 aaaatcctca ttatggaaat gcaggagttt tactttcgga agttgagtat tttgttaaaa
    23101 aatttgaatc cctaggtgta aacagttttc atgtaacact tgcaaatcat tcaaaattag
    23161 aagatactat accaaccaat aatcatcctt actttaaaga agaaggctgt tttttatatt
    23221 tagctgatga agtaaagaaa cacacaaatc ttccagtatg tggggttgga aaattgtcta
    23281 gcccagattt tatagaaagt attatttcaa ataatagagt agatatggtt tctatgtcaa
    23341 gacaattact agcagatagg aattggttac agaaagtaaa agatggaaga gtagatgaga
    23401 ttaaaaagtg ctgttattgt aataagaagt gtgcagatgc tttacaaaca cgctctcagt
    23461 ttggatgtat actagattag aatatcctta taaaaataaa taatttgtta aggttaatat
    23521 atttttggtg atttagataa gtatttagat aaagaggagg agacatcatg aaaagtttag
    23581 ttttatattc aagtttaact ggaaatacta aaaagattgc ttatactata tatgatgaaa
    23641 ttcaagaaga aaaagacatt aaagatgtaa atgaattagt tgattatagt attgactatg
    23701 aaaattatga tatagtattc ttaggctatt gggtggacaa gggaatttgt gataaaaatt
    23761 caaaacaagt gcttgaaaat attcacaata aaaagatagc actatttgga acaatgggag
    23821 caagtaaaaa aggaagttat ggagctagta taatagaaaa gatagaatca attatcccaa
    23881 aagataatga aatattaggt tcattcatat gtcaaggtaa gatagcagaa ggattgaaag
    23941 caaaatataa agagatgtta aaactttctc ctgacaacga acatattcgc caacaattaa
    24001 ataaccatga ggaatctcaa agtcatccag atgaacaaga aatatatgaa gccagtatgt
    24061 ttgcaaaaaa tatgatgatt aaagctagta ttgtgtagta gttaaacaat aagttcatat
    24121 aagatataga ataaataatt tagtaaaaaa gtatagcaaa taatttgcta tgcttttttt
    24181 atgaaatcaa aaaaataata aaaatacttg actgtaaacc ttgtttatac attattttat
    24241 agaaaataag atagttttaa atataaaaaa agatatatta ttgaaaggag atattattgt
    24301 atgaaaactt ataaaagata attagtttga ttttaagata tactaaatat acaattttat
    24361 agagtgaaaa tatttaagac tatattatag ttataaatta atagaataga gaggtagtgt
    24421 ttaaattgca ataacagtat ttccaaagtt gccacctcaa attcctatcc aatggaataa
    24481 tggtgtagct aattatgtag ataaaaaatt tatttatgcc taccctgtca tttgtgttgt
    24541 attcagaatc cttttacgtc catttatatg gagatggtta caaatacatg ctttttatag
    24601 tgacactatt gcagattatt taacgaattt tatgtgtttt gtagcgttgt ctatagaaat
    24661 attctctata ctttttattt acaatattgc cagacatgtt acaataatta tttttataga
    24721 tatacttgta tttattgctt tactgataat aggtatgtat aaattattta aaaaatacaa
    24781 ttaattttta aaaattaagt aataagtgat agtgtaaaaa gtagccactg caaattatgg
    24841 attgtagtgg ctattttatt atttgtatat gaaattattt tgtttttcta ataagttacg
    24901 atatattatg gtttatttca ctgataaaag gtttaggtat tttaaagtaa aaagttgtat
    24961 attctaataa aatttaaaca ttttgattct ttaaaattag agaaaataca ttgttcttat
    25021 taaaaaatta aatattaaga atttaatttc tgcatcttat ttagaaaaga taagaaatca
    25081 actttatata tttttttggg ccttcctctt tgattatcga gttttgtatt tacaatagtt
    25141 gcaattcctg ctttatataa gatactcaat attctattag cacttctaag agttatgttc
    25201 atatagtttg ataatatttc tgctgacaca ttatttgaat ttctatcatt aatcatacac
    25261 atgattttag atacatttgt attagataga ggtataaaag aagcaacttt attggctatt
    25321 gagctatctt caatattatt agaattttta tttgaatata aagggcctat tgtatcatta
    25381 gtatcattta ctataaaagt acagtttcca ttcaaagaag cagatttacc attagcttga
    25441 cgagcatttt gctctgcatg aatatttgta tttccaatgc cccaacctat atttaagcta
    25501 tatttaattt cttttaaatc ttctgaaata aaaaaatctg tatagttatt ggtcatattg
    25561 tttaacattt ctttagtagt gtgtatctct attttcatat catttttttt gacctgaact
    25621 ccataaaatc catgtcttga tagagaattt aatatagtgt tatatatttg attttgtatc
    25681 tcatcatttt taaatatcaa atcttcattt atgtactctg aactatttac tgtaactata
    25741 caagttgcag atttattttt gtctaagttt tgtaatgtta tttcattcac cagagattta
    25801 aatgtattca ggattgattc tgtagatgga accatgtaaa tacaatcata tccaagttta
    25861 ttaagttcac aactaatgat gtaatttcta gtaaaagaaa ggttaatctt attatctcgc
    25921 aataagtcta aatgtatttc caataattta tcatttaatt ttttaaagtc atatacaggt
    25981 tgagggatat taaaatcttt aattgtatat ggacatttat tagagtctat taatgaatat
    26041 atatcataat aattgttgtc ctctcttaaa aaatccataa atgattttgt aaagtcaata
    26101 tctttttggc tatttaataa tttgaataag tatttataaa aatctctttc atcaagcttt
    26161 aaaaaattta atggaacttt tatgtctttt atatttatta taagttcact atatggaact
    26221 ataccactgc atacaaatcc atcaaaatta tctacttgct catagtatat attaggtaaa
    26281 ttattaaaag gattctcccc tttgagctca ataaatgtaa tttcacaagt atcatttaat
    26341 tctttaagag cttgtttaaa cttatctgac ataaaataag atgttgtcaa aaaaccaatt
    26401 ttatatttca taaaacctcc tttaaaattt cgagagtata gtaactaatc aatcaattta
    26461 taacctcatt ttataatagt agataaaacg cgtcaattta ttttacaaaa ggaaaattta
    26521 aagaaaaatc agaaaatata aaaaagactg aaaaatatgt tgactgtcaa gaataattgt
    26581 gctattttgt aattaaggac tagtctttta agatttccta aaataaactt agattttagg
    26641 aaagaaatac attttatttg aaaataaagg agaagattat gaatacatat ttaaatgaaa
    26701 tttctaagtt tgttgatgag aatagagaag aaatagtttc attatggaaa gagattgtta
    26761 atatagaaag ctatacacat tgtaaagaaa gcgtaaataa attggctaag agattaaagt
    26821 ttgagtttga aaaagaaggt ttagattgcg agttagtaga tgttggagat aatggtagta
    26881 cattgatagg tacacttggt tctaatataa ataaaaagcc tataattttt tcaggtcaca
    26941 tggatactgt ctttgaaaca ggtacatttg gagagaatcc atttaaaata atagaaggaa
    27001 aagcatatgg cccaggtgtt ttagatatga agggtggtat aataatttcc ttatatgtta
    27061 ttaaagcatt aaataaaata ggatacaaag aaagaccaat aaaaatagta ttttctggag
    27121 atgaagagat aggacataag gattcaacag gtgcagatgt tatattgagg gaagcaaaag
    27181 gtggtctttg tgcttttaat atggaaactg gattagtaga taatagtttg tgtgtaggta
    27241 gaaaaggaag aataggatgt aatatacatg taaaaggtgt agaaacacac gcaggtaatg
    27301 attttgaagg tggaagaaat gctatagaag aaatggctaa taagatacta cgcatacaaa
    27361 aattgactaa tttagatgtt ggaactacag taagtgtaag tgtgattaag ggtggaagag
    27421 tggaaaattc tattccagaa gattgtagta taaaagtaga ccttagattt gaaaaagtag
    27481 aagaaatgga gaatgttaaa gaacaagtta gagagatatg taaagaaact tacatagaag
    27541 gaacttctac agaagttaat tttataagtg aaatgatgcc atttgaaact acagaagatg
    27601 ttatgagatt tcatacattt gtaaatgaag tgtcaaaaga aaatggattt ggagaattaa
    27661 atgctaagag acttggaggt agttcagatg ctagttattt gactattgca aacgttcccg
    27721 caatctgttc atttggtgta agaggggaat ggaaccacac atcaagagaa tatgcagtag
    27781 tagattctat gtttgagagg gtgaaattaa tttctacagt tattttaaac ttagataaat
    27841 ttgaggtata aagggggatt ttatatggat gtaacagctg gagataataa ggtaacatgg
    27901 aaagggtatt tatctttatt tgtattgata gtattatttt caggagtgtt taaagatagt
    27961 caaggcttcc ttaaagcatt agattttgct aatctgacag gttcatttgg tactattgca
    28021 gatggtgtag actttatggg taaaggagga acgggagcaa aagatggttt cttatttgct
    28081 ctgactttga ttccaactgt ctgttttgct gtaggtctta tagatgtagt tgaatctatg
    28141 ggaggaatga aagcggcatc aaagatattt aatccattgc ttagacctct gcttggtata
    28201 cctggaatag caggaatagc atttgtatct tcatttacta gttcagatgt agcctcaata
    28261 atgacgaaag aattatttga aagtggggaa ataacagatg atgaaagaac tatatttgta
    28321 gcatatcaat atgctggttc agctgttata ctgaacacaa taaatactca agctccactt
    28381 ttaccaatag cattattggc attaggtcca ataatcctta tagagatatt ctgtaaaata
    28441 cttggtgcta atctagttag attaatcata ggtgtaagaa ataaaaagaa taaggctaag
    28501 gaggctgtgt agtatgagtc aacaaaatac tggaaatgca attgtaaata gtaaacctaa
    28561 gaaaactgct gttgagatat ttatgggggg agcaaaaaaa ggtttttaca taggtgttga
    28621 acagatatta ccagccatga taatgggtta tgtaatagtg cagtttttac aattaactgg
    28681 tttagttgat attttaggaa atatttttgg accagtaatg ggtatttttg gactacctgg
    28741 ggaatctgtt ttagttttga tagcagcatt ctttgctaag gcagcaggag cagctacagc
    28801 tgcaaactta tttgcacaag gtctaatcac tgcaccacaa gcaaccatat taattatgcc
    28861 atgtatgtta atgggtactc tagttggtca ttatgccaga atagtgcttg tagcaaatgc
    28921 cagtactaag tatagaatgt tactgttggc agttcctata tttgatgcaa tagtggggat
    28981 gttaatagta agagttttac tcactgttat gggattaatg taaataacat aaaattataa
    29041 cctaactata aatgatatat aagaattaat atatacaagg attaatgagt agtaattgat
    29101 atatagtaat aaactaagat agtaattaat gtgtatatta attaaaaaaa gagagtatct
    29161 caaagtgaac tttttagttc atgagatact ctttttgtat gaaatcaagt atattttcat
    29221 aatttcaaca atgaaagaga ggcttatctc tattttgaga cagcctcttc ttttaaattt
    29281 atatttctag aatttatgtt ttttatttat ccaacattaa cattagttat tagaaataat
    29341 tttaagaaaa atatactttc atgttaatat cagaataaat ctgtttttaa aggatgattt
    29401 gttttgaatt ttcacgaata tctacttcta tgactttttc tattgtatct cctctaaaac
    29461 ctaataaatt acttgtcaag tttgcagtgg aacaagaatg attaggtata attcttattc
    29521 tatcaccaat ttttatatca gtttcaccat ttactttaat ttttccaact tcttctgaaa
    29581 gtgaatcaat agtaagttct ggatgtccac ataccctacc ataaccaaca atactactat
    29641 ttccatgtgc acctttatca agtccaaggc acttacttcc acaatcaatt aaatagtatc
    29701 cactgctatt ttttgagatt acagtgcaca caacagtaag agcacacata tcttcagtag
    29761 cacaacctaa acctatctgt atagcatcat agtatacata gtttccaggt cttacagcag
    29821 ttatagtttt agaagcagct tcagattcaa ctgttggagt actaccagaa gcgacaattt
    29881 ctatattaaa tccattatca gttagagctt tgtatgcttt ctccatagaa gaatcttctt
    29941 gaacacaaac atctggaaca ccttctggag aactacaacc atacacttga cctggatgcg
    30001 aacttatacc aacaatcttt atgttttcta gcttagaaat ttcagtagca agttcaacca
    30061 ctttctctgg ttcaacccca aaacggtgta agccacaatc tacaataata agtagcttgc
    30121 actctatttt tgatttagaa aaagcttcac tataagcctt agcacattct atattatctg
    30181 tagcacagat taaatttatt tttgatgcca tagtcacaat tctatttata tttacttctc
    30241 ccatgtaagg ataagccaac ataatatctt caaaacctgc ttttatcaga gcttcacctt
    30301 catcaagtgt tccaactaga aaaccactag cacctgcatt tttttgaagt ctcgctatgt
    30361 aagtactttt atgtgtctta agcataggcc aaagttgttt attattattt gtacaaattt
    30421 gttgaatttt atctatattc ttttctaact ggtctaaatc tagcaaaaaa tttggagtag
    30481 cgacttctga aattttcatg ttatttacca cctttcaaca aaagtaaatt aactataagt
    30541 attataatta ttatattagt aatatcgtct ttataatatt aatagcttat aattatatta
    30601 tagaactagc gttaacagag agcaatattt atttgtaata attagaattt tcaataagtt
    30661 agtgtggttt taaattattt atataatata tttttaattt tatgcaaagt ttatttaaat
    30721 tagtttgagg atttattaat agggtattat tgaatgagta aaaaagtgat gtttacatag
    30781 aataatcaca ctataaatta atttagaacc taaaaaatta attgagcaaa ttggaaaaga
    30841 gaaggataaa aaagatattt ggatagttgg tggaggcgat atagtaaaat tatttatgaa
    30901 agataactta attgatgatt attatatata tatattgcca ataatattgg ggagagggat
    30961 ttcactattt aagtctggta tagataagac taatttgaat tttaagaaag ctagtaatat
    31021 tggagaactt gtaaaattgg aatacagtaa aaaacaaaaa taaattacat gccaatttgt
    31081 tacaatgtta tgaaatgaag catttaaaag acttttggct atatgaattg acattacttg
    31141 tcaaatatgt taacatataa gcgacttgtc ggagggtgta ttaaaaagaa tatgctggag
    31201 aagagagtgc gttaactctt ttctcctttt tttataaaat taagcattta taaatttagt
    31261 attattacat gattacacta tctcaaaaat taagaaagga gaaaaatatg aaattaattt
    31321 taagttattt aaagaattat aagttattaa tagtattaaa catactggct atatttagtt
    31381 ttgcattagt cgagttgggg attccaacta taatagctaa aataattgac aatggtattg
    31441 caaatcagaa tatagcttac ataaaacaaa tgggaatagt gattgttatt atttctatta
    31501 taggggttgt aggtagtata ttgttgggtt attgttctgc taaggtatca acaagtgtaa
    31561 ccagagatat aagaaatgac atatttgaga aatcacaaga attttcacat actgaataca
    31621 ataaatttgg aatttcttca atgattacaa gaacaacgaa tgatgcattt caaattcaac
    31681 aatttgttaa tatactacta aggactgcct tattaactcc agttatgttc attataagta
    31741 taataatgac aattagaaca agtgtggaac tttctatagt attggctata tcagtacctt
    31801 ttataattat tggagtagca ataatagcaa aagtatctca ggcaatatct tcaaaacaac
    31861 aaaaaggact agataaatta aaccttatat cgagagaaaa tttaactgga ataagagtaa
    31921 ttagagcttt tggaaatgat gattatgaaa cagagcgatt tgaaaaaaca aatacatatt
    31981 atgctaatgt ttctaagaaa ctatttaagc ttatgtcaat tactcaacca gcattctttt
    32041 tactattaaa tatagctgtt ttggctgtat tttggatttc aagtgagaag ataaatattg
    32101 gagagcttca agttggacag ttggttgcat ttttggaata tcttttccat gccatgtttt
    32161 caattatgct tttttcaatg gtatttatta tgtatccaag agcagaggta tctgcaaata
    32221 gaataaaaga acttttaaat gaagaaccat tgataaaaaa tcctgaaaat ggaattaagg
    32281 atactgaaaa taagggtatc atagaatttg ataatgtaac ttttacctat ccagatggag
    32341 aagcttctgt acttaaggat atttcattta ctgcaaaaac aggtgaaaca gttgctttta
    32401 taggaagtac tggtagtggg aaaagtactc taattaactt gatacctaga ttttatgatg
    32461 taacagaagg tagtattaag ataaatggag tagatataag agaatatgat ttaaaagctt
    32521 taagaaaaaa gataggattc atacctcaaa aatcactgct ttttactggt agcatagcaa
    32581 ataatattag atttgggaaa cataaggcag gagagtcaga attagaatat tccgcaaaag
    32641 ttgcacaagc atatgagttt atatcaaaaa aacctagaaa gtttgatgaa ttgattagtg
    32701 aaggtggagc aaatgtatca ggaggtcaaa aacaaagact ttctattgca agggctatta
    32761 taagaagacc tgaaatatac atttttgatg atagtttttc tgcacttgac tttaaaactg
    32821 atgcaatact tcgtgctaaa ttgaagaagg aaacaaaaga tgcaattgta ttgattgttg
    32881 cccagagaat tagttctatt attgatgctg ataagattat agtactcaat gaaggacaag
    32941 ttgtaggaat gggaactcat aaagaattat taaaaaactg tgaaatatac tatgaaattg
    33001 caacatctca gttaaaaaag gaggaattag aataatgaaa aagtctaaag gttttaagaa
    33061 aacaattggt agacttcttc catttgtaaa gaaatataaa ttttccttta ttatagctat
    33121 tatatgtata atttcagcag ctactatgaa tgcacttgca cctaaaactg aaggattgat
    33181 aataacacaa ttgactaaag atgtaattag tatcgcaaaa ggagtaccag gggcttccgt
    33241 aaattttgat tatgtaacaa aaatattggt gattttagca tgtatatatt ttgccaatgc
    33301 aatttttacg tatacttcaa gttttctact taccaatgct attcaaaaca caatgagaga
    33361 tttaagaaat gaagtcgaaa ataaaataag aagattgcct attagttatt ttgatagtaa
    33421 tagttttgga gatgtattaa gtcgtatatc aaatgatgta gatacaatat caaatgcatt
    33481 gcagcagagt tttatgcaaa ttgtaaactc aatcttagtc ataattttgg cactttcaat
    33541 gatgtttaca attaatatat atatggctct tatagctctt tttataattc caattagtta
    33601 ttttgtatct aaatttgtag taaaaaaatc tcaaagtaga ttttcattgc aacaaaatgc
    33661 tcttggaaaa ttaaatggga aagtacaaga aatgtatact ggatttaatg aaataaaact
    33721 atatggtaaa gaagaagatt ctataaaaga atttaaaaaa gtaaatcaag aactttgtga
    33781 aaatggattt aaggcacaat ttatatcaag tatgatgaat cctatggttt cattagtaac
    33841 ttactttgga attgcagctg tggcagttgt cggttctata tatgcagtaa gtggaggaat
    33901 aacagtagga aatttacaag catttgtgcg ttatatatgg cagataaatc agccactttc
    33961 acaaatgact cagttatcta cagtaataca atcttctttt gcagctatag aacgtgtatt
    34021 tgaaatttta gacgaagaag aggaaatacc tgatgttgaa aatccagtta agatagaaaa
    34081 tgtaaaagga aatgttacat ttgagcatgt taattttgga tatggagaaa attcaacttt
    34141 aatagaagat ttaaatgcag aagtaaaaag tggtcagatg gtagctattg ttggacctac
    34201 tggagcaggt aaaacaacat taataaactt attgatgagg ttttatgatg taaagaaagg
    34261 tgctattaaa attgatggag tagatataag agatatgaaa cgtaaagatt tgcgttcaat
    34321 gtttggtatg gtgcttcaag atacatggtt atttaatgga accatttttg aaaatataga
    34381 atatggtaga tttggagcta ctaaagaaga aattatacaa gcagcaaaag tagcaaatgt
    34441 tcatcacttt ataaccactc ttccagatgg atacaatatg tttttaaatg aagaagcatc
    34501 taatatatct ctaggggaaa aacagctttt aaccatagct agagctttta tatcagaccc
    34561 ttcaatattg atacttgatg aagctacgag ttctgttgat actaggctgg aacttatgct
    34621 tcaaaaagca atgagaaatc ttatgaatgg tagaactagt tttgttatag cacatagact
    34681 ttctacaatt cgcaatgctg acttgatttt agttatgaat aatggaagta ttatagagca
    34741 ggggaatcat gatgaattaa tggaaaaggg tggattttat gagaagcttt ataatagcca
    34801 atttgcagac aaagaatcag aatagataac ataaactttt gtataaaatt ttgtatcaaa
    34861 ttcaaatatt aatcatataa ttaaaaagag tatcagtaag ttgttttttt atagatttac
    34921 tgatactctt tgattttaag accaaaggta cttatgattg gtacttataa ttcacaacta
    34981 gtcttgttac atctgataac cagaattaca gtacttttct tttttacctt tttgttctct
    35041 aacatataac aattcgctta acttatcaat gtaataacca tcatcactta tgcgaattaa
    35101 actagtcaga taatatccat ctttgcttct aggaatcttt ttatttattg ctaaatcaat
    35161 agctgtcttt gctgcttcaa aatgctttaa atgtgtatga ccttcttcaa aactctttct
    35221 agtattataa actacataac cttttttaac ttgaaaaact ataaattctt tcttttcata
    35281 tattttatta aacattcaat cagcccttct caagatagtt ttatagcata acattagaag
    35341 cttctaaaaa attttacaaa gaacataaat attttataaa ttataaatct aaaactataa
    35401 tttataaaga taactttctg attatttata tgataattca tatagattaa aagtaaatta
    35461 tctttaggtt aaacaaaagt aaaataaaag actagttata atatttatat gaaaaagtac
    35521 aaaatatagt atatgaatat agaaaattta aattatttat ttacagtttt tatttccata
    35581 agtatattta ccttcagata ccttgtcatc atggaaatat attctttcac aacttttatc
    35641 tccccataga atgttttttg ttattttatg ggacgtatct cctgtaaata cttcagctac
    35701 agtagtatct gtaacatcac agtaaagaga agcgaatttt ttaaaccaag gattttcctc
    35761 aaatcttaaa agccaggaag ctccataggg gcaatgtaac tcttcaaatt caggaaccca
    35821 tcctagaaat ggaacatcag ttgtgctaat aatattgtct gcaattaatt catctccatt
    35881 ttcatgagct ctctctctca tagcaatagc tctttcttca gacctttcaa ataaaacttt
    35941 tcttaatatt tcgctagttt tatcttcacc aaactcttca aataacactt tggaaaaata
    36001 aaaatataaa tcaccaaaat gtttgcatgc catacgaact tcttcaatag cataatcttt
    36061 gtcaatagtt tcattagtta caacatcttc gttcaaaaaa atcactcctt agaataagta
    36121 ttagttacaa tataattata gaatattttt tataaattag gaaattaatt tgagatagat
    36181 atatttttaa taaatgaaag tataatgcta aaataactta ttgttacaaa aatcttctaa
    36241 attaatgtat ttaggagttt ccatatgaat gagagtagtt ctgtaaatat cttcaataca
    36301 tccatttgca atattattaa aaatatctgt gtgctctttt aatgttgttt caagccttcc
    36361 ttcatgtgac aatgaatcga gagctaattt ttttattctg tacatataat tgttaaacat
    36421 tttgtcaaat tcagtatttt gagcatatga aactatagtt gtgtgaaata atgtatcgta
    36481 ttctgcaaat gagtttaaat ttttatcacc taataaaata tctttttgtt tatctaaaag
    36541 atgttttaat ttacttatag tttctactgc tctagcttct ttgtattgac ttgtaattaa
    36601 aaaagtacaa aatccttcta ttgcagagcg tatttggaat atctctacaa tttcatttgc
    36661 tgtaatttga tggattctaa atcctttgct tgggattata tctataaatc catcttgact
    36721 aagtctttga agagcatctc ttataggtgt tctagagata cctatttcac tagcaagttt
    36781 tgtttcagaa tatatttcat tttctatcat ttctccagat agtatcaatt cttttaagta
    36841 gtcatatgct tgttcttgta atcttttaaa tgtagccata cttaataata cccccctaaa
    36901 caatataaaa atacaaaaac ttatataatt ttaagcatac aacatagtga aaataaggtc
    36961 aatcttttgc aatttaaatt gcagataaga ttaaaaaata taaaaaatta ttgaagtgtg
    37021 aagcatgatt aacattaaag gcagattaat taaaactaat tgaaattagt taaaatacaa
    37081 aactgtaaaa gtagtatatt atatttgaaa acaatagtat gtattaaaac ttatatagga
    37141 tgactaaata taataaatga ctttaaaaat tactatttat tgttaaaata aatactttta
    37201 tattttatat tgaccggtat actggtatgt agtatactct aaaacataaa aaacgttttc
    37261 aaaaatgtga agatatggag ggttataaaa tgaaattggg atttattgga ttaggaataa
    37321 tgggaaagcc aatggcaaaa aatttattaa aagatggatg taatcttttg gtgtatgaca
    37381 ttaataaatc tgctgtggat gaacttatat catgtggagc aaaatacgca agtgttttag
    37441 aaatgggtca agaatgtgat attgtattta caatccttcc aaatggaact attgtgcagg
    37501 atatattgtt tgggatggat ggattggcaa aaactttaaa agaaggaagt atagtagtcg
    37561 atatgagttc agttactcct acagaatcca tattgtgtgc aaataaatta aaagatatgg
    37621 gcttagaatt tatagactca ccagtaagtg gaggggagcc aaaagcgatt gatggtacac
    37681 ttgcttttat ggctggtggt aaggaagaaa tttataagaa agtagaacca ttttttaata
    37741 taatgggaag ctcatctatt ttaattggag ataatggtag tggaagtgtt acaaaactta
    37801 caaaccaagt aattgttaat ttgacgatag cagcagtttc tgaggcattt gtacttgcag
    37861 caaaagcagg tgcagaccca gaaaaagtat ataaggcaat aagaggaggc ctagctggta
    37921 gtacaatatt ggatgcgaag ataccaatga ttatgaatcg tgattttaaa ccaggtggga
    37981 aaatatctat taatttgaaa gatattaaga atgtaatgca aacagcacac aatttagatg
    38041 taccactacc tatgacaagt caattattag aaattatgca gacattaaaa gtacatggac
    38101 atttggaaga tgaccatagt ggaatagcac agtattttga aaagttggca ggtgttgaaa
    38161 taaaaaaaca caataattaa tatttaaata tatcaatata attaaataca tattattagg
    38221 attagattat ataaatacag cgaggttaag ttatcatagt aaaagaaaaa taaaattgat
    38281 aaataataaa gtagaatgat aaaggggtaa agattatgat tacaggatat ggacttttga
    38341 tagcatttgt tatatctata ggaattttac ttgtatcgat tattaaattt aaagtaaatc
    38401 cgtttttggc attactgata acatctataa ttacaggctt tatggttaga atgcctataa
    38461 atgaaatatc aaccacaata tcgactggat ttggaaatac attaggtagt ataggtattg
    38521 taattggact tggaataata tttggaaata ttctttcaga atcaagagca acagaatcta
    38581 ttgcaaaggg gttgttagct aagactggag aaaaaaacag tgctttagca gtaactacag
    38641 caggtttttt aatttcaatt ccagttttta tggatgcagc ttttgttata atgatgccta
    38701 taattaagta tgtttcgaga gtaactaaga aatctctaat ggtttttgta tgtgccttag
    38761 gagttgggac tatagtaggt catgcacttg taatacctac accaggacct ttagcagttg
    38821 cagcaaatgt aaatgcaaat gtaggtagtt ttatacttta ttctataatt gttgcttttc
    38881 cagcagctct tataggtgga tggatttatg gaaaacgttt tgaaaaatat ccagcttatg
    38941 ctattgatga gaatgataga gaaaaaaatt tagagcaggg aaaagatagc ataaaaattg
    39001 aagatgatga ttcttctaaa gtaccaggtt ttggaatttc tatgttttct ttattgttcc
    39061 caatacttct tatacttata tcaaatgtat ttagtatgtt cttagaaaaa ggttctacaa
    39121 tgagtggagt acttgcattt ataggagata aaaacatagc aatacttctt ggaatattgg
    39181 tggcaatagg atttttaaag aaatacataa ataaacctat gggagatgta gttattgaag
    39241 ctgctgattc agcagggcta atattattga taacagggtc aggtggtgcg tttggcagtg
    39301 ttataaatgc aagtggtata ggtaacttct tagttgatac tatgtctggt cttagtatat
    39361 cagttgtagt gcttggattc ttattaagtg ccttgcttag aatttctcaa ggttctgcta
    39421 ctgtagcctt agtaacaaca tcatcaattt taggacctac aattttggca actggaatgt
    39481 caccagtttt agtagggctt gctatatgtg ctggaggagt tggtttctcc cttccaaatg
    39541 attctggatt ctgggtactt tcaagattta gtggattatc agttaaagat actttaaact
    39601 cttggacaat tggaggaacc attgctggag ttgtagcatt tataatggtt ttattgctta
    39661 gtgttataaa tggaattata ccacttccag gtctataaat aacaaactat tgtttatatc
    39721 atataaatta catttagact atacaaatta cataaagggg cgttttaaat gagagaagta
    39781 aaaccaatta gcatagatat acttaatact tttaaacaag tagatgagga cagattaaat
    39841 aaacttcttg cagatgagct taagcattta gatagaaaaa ttgttgtatt agatgatgac
    39901 ccaacaggtg tacaaacagt tcatgatatt tctgtttata ctgattggga taaggatagt
    39961 atggaacaag gttttaatga gaaaaatagt atgtttttta tacttaccaa ttcaagggga
    40021 tttactgttg ctcaaactac aaaagcacat aaagaaattt caaagaatat tgtggatgta
    40081 tcaaagaaag ttaataagga ttttataatc ataagtcgta gtgattctac tatgagagga
    40141 cattatcctc ttgaaactaa tttattaaaa agcgaagtag agagattatc ggagaagtta
    40201 tttcagggtg aaataataat gccatttttt aaagaaggtg gtaggtttac tatagataat
    40261 gtacattatg ttaaagaagg agaaatactt gtaccagcag gaatgactga atttgcaaaa
    40321 gataaatctt ttggatataa atcatctgat ataggtgagt ggtgtgaaga aaagacaaat
    40381 ggaaagtaca aatctagtga tatgatatat atttcgtcaa aagaacttag agagctaaat
    40441 attgaagcta taacagaaaa acttaaaaaa gctgaaggat tcaataaaat tattgtaaat
    40501 gcaaccgatt atgtagatgt aaaggtattt acaattgcgt ttatacgagc agtaaatagt
    40561 ggtaaggaat ttatgtttag aagcgctgct gccataacaa aaatacttgg cggagtgagt
    40621 gacaaggaac tacttactaa ggatgaatta gtatcaaaag gtaataccaa tggaggaatt
    40681 atacttgttg gttcacatgt gaataagact acccaacagt tagaagaact taaaaattgt
    40741 aaatatccga tagaatttat agaatttaat caacatttag ttcttcaaga aaatggtcta
    40801 aaaaatgagg taaaaagagt tataaaagtt gtagaggaaa aaataagcag gggtaaaact
    40861 gttgctgttt atactagacg agagcgtttt gacttggata cgaatgataa agataaacag
    40921 cttatgattt ctgtagaaat atcagatgca gttaccagta taattggtat gcttaatgta
    40981 agaccaaatt ttattatagc taagggtgga attacttcta gtgatgttgg tactaaagca
    41041 ctaagagtaa aaaaagctac agtaatggga cagataaaac ctggtatacc agtatggatg
    41101 acaggcaaag aaagcaaatt tcctaatatg ccatatataa ttttccctgg aaatgtggga
    41161 gagattagca cacttagaga atcagttgag atattgatgg ggtagtatat tagtgtattg
    41221 aagtttaaac gcttaaattt actgagttaa aattaaaata aactaaaatt ataaattaag
    41281 attaaaaata atagtatatt aattagggtt tagagtattt tacaaaaaat attctaaacc
    41341 ttaatcttat gtattagtat ttttattatt taacttatgt gtttatttta ttatttatct
    41401 tttttaattg atttaatatt ttctttgatt ttatttaaaa tatctgtatg cttattagag
    41461 cttatgttgg ggaatgcttt gattatacgt ctatgaagta atttgtggtt agacagcaaa
    41521 gtattaagtt tattttttag ctcatcaata cgatttttag catagcgata attttctttt
    41581 tctttaagta tttcaaacct atcttccaaa gtatccagtc tattttcaac taaagattca
    41641 agtttgtttt ctatagtttc ttgtgtaata agtttgtagt attctttctt atcttttaat
    41701 tccttaatta taagattgat ttgttttaac ttaccattta attgtaaaat tgtatggact
    41761 gtgataacta aatctaaaac aaaataaatt tctatagata tagcaaatat aaatagcaca
    41821 tttttagaga tagagttaat aaagtcaacc acaataggat gtactataag cattacaatc
    41881 aatgataata caccaaacat aagtgagttt tccagacaaa ctcttccgtg aatattaaat
    41941 ttatgtttag aataatccca ccaagtcata ttaaatattt tttctaaaat aaagctcgta
    42001 caatactcca ttatgctagt tataattata ctaaacaaaa acaacaaagg aatagtgtgt
    42061 acaaaaggag tcaaggtagc aactattgct aatgctccaa atccatatat agggcaaaat
    42121 ggaccattta aaaaacctct atttacaaat tgtttttgta aaactgaaca atatgtagtt
    42181 tcacaacacc atcctataaa gctataaatt acaaaataaa gaaattgaat ataaaatgta
    42241 ctcataagca cctcatttct agttagtata acactatata ctcgatattt tatttttatg
    42301 attaatttac taaattcaat ttacatattg attataccaa tttatagaaa tttatcaaat
    42361 ttaattacag ttagaacatt ataaacatgg ttataataat gaaattttat ttaaaataaa
    42421 taagggtgtc aagtataatc aaactaatag ttgtagatac tctacactat gttagtttaa
    42481 ttacatttga cacccttata tttatactat gactatttac attcgaaact agagcaacat
    42541 gtttcaatat aaaggtttac tctatcagtt tcaggagcaa ccaatatatt atcaagtgta
    42601 cataagctac catctttgtt gtatttacaa ttttttacag tacaaactaa ttcctcacaa
    42661 tttctattat taacgttgct agataaatta ctataaatag attcatctaa aaatgaacta
    42721 caacaagtat gtctgtcatt gtgagctttt tcaccattta taaaaatttt atctgcataa
    42781 catatatggc tgttgttatg tgaacagtta attacattac agtttattct ttccaaagtt
    42841 attacctcct aaacgattat ttattataaa ttatgtccat ataattacaa gaatataacc
    42901 attaagagaa aactaccttt tagaaaatat ctattcttag agtaatttga aatataaata
    42961 tattttcttc taaaatttac ctaaattgta taaaaactta cagcttggag aaaataatag
    43021 aaaaaggagg cgtaatcaat gtttgaaaag aagaaaaaag aattatttcc ttggaaaata
    43081 tctgccttaa tactggttgg agtatttgta ttaagtagcg gagtttatat agggacaaga
    43141 ttaaaacaca atggagttca aactggtgaa gttgtaagta ctagtgcgaa tatgaatgaa
    43201 aagtcaaaag aagcttttgg attaaataaa aattgtgaag tttggcttca aagtgaaggc
    43261 gaaaatgaaa ctaactataa gagaacactt acaatggcag gaatagttcc agagtcatta
    43321 ttagataaga cgaagtcaga aatagtatca tattttaaaa aagaatatcc aactaaaaaa
    43381 ataaagagta tggataaaaa tgaaatcata ttggtagaat ctaaatatag tgataataaa
    43441 gatgtacaag caatggatgt tactataaaa ggtaaatata ctattgaaaa tgataatgga
    43501 aatatagcac tatataaata tgatgatagt ggaagcaaaa cattagtaga aaaaacaaaa
    43561 ataagagtag attcacttcc taaaacagtt caagatgaaa tcaaaaaagg tgtagttatg
    43621 gatactgaag aagaggccta ttcaagatta gaagactttg caagttaata gtaaattaat
    43681 attattttaa gttaaatact aagtaagtta aatactaagt aaattaataa taaataattt
    43741 aatattaaat agattagtat taaatagatt agtattaaaa ttgtagtcac atttaattcc
    43801 tataaaaata caataattta tttgtaataa atataaaagt tatattgagg taaaatcttg
    43861 ctttgatata acttttttat ttgattttat attttacata gagcatttta tgatttgtta
    43921 atattattta tgatataatg atttagaaca taagttttta tgagaaatac attttggtat
    43981 ttcttttatt tttaggggga attttaaaaa atgataatat tggggattga cccaggtata
    44041 gccatagttg gatatggtat aattgaatac aaaaatagca agtttaaagt aatcgattat
    44101 ggagcagtta caacacctgc ccatatgaat atatcgagaa gattggaact tgtgtataaa
    44161 ggaattgata caatagtaaa gaattacaat atagatgaag ttggaatgga agaattattc
    44221 tttaacaaga atgtaaaaac agctataaca gttgcacaag ctagaggtgt tactatgctt
    44281 gcatgtgctc ataatgggaa gcctgtatat gaatacactc cacttcaagt aaaacaaggt
    44341 gtagttggat atgggagagc agataaggca caagttcaac agatggtaac ttcattttta
    44401 agtctaaaaa aagttccaaa accagatgat gttgcagatg ctttagctgt ggctatttgc
    44461 catgctcatt caaacaaact tgaaaaaact ctaaagaata taggtggtaa gtatgtatag
    44521 ttatataaaa ggtacagtag aagaaattta tatagacagt atagttgttg aaaataatgg
    44581 gataggatat aaaataaatg tatcatccaa tacaataatg aatttacaag tgggagaagc
    44641 cacaaaaata tatactaaat taattgtaag agaagatgat atgagtcttt gtggttttgt
    44701 aagtagggaa gaacttaaga tgtttgaact actaacatcc gtatctaaaa taggacctaa
    44761 ggtggcgctt tcaatactat catttgcatc accagcacag ttaggagcat atattttaag
    44821 tgaagacatt ggaaaattat ccaaagctcc tggtgttggt aaaaagacag cagaaagaat
    44881 cgtcttagag cttaaggata aggtagacaa aaataacata gagtttgaac caacgttatt
    44941 atcacaaaaa cctaccttga tatcacaaga tgagtctgta gatgcacttg tagctttagg
    45001 ctatactttg tcggaatcaa aagaggcagt tcaaaaatgt aaaaaagatg gtatgaatac
    45061 agaagctatt ataaagaaag cacttacata tataatgagt aaatccttga aatagtattt
    45121 ggattttata atatttggat tttaaaacaa tattttaagg agtttatgta aatttgaaaa
    45181 tatataaagt agattttcaa aagtacgaga ggaggggtat aaatgcaagg ttttgaagat
    45241 gaaaatagga taataacttc tacaatgaag atggaagata tagatataga aaacagttta
    45301 agaccaaaaa ctttagaaga ttatttgggt caagaaaaat ctaaagaaca acttagtata
    45361 tttatagaag cagctaaatc gagaaatgag cagttagacc atgtgctttt atatggacca
    45421 ccaggtcttg gaaaaactac actagccagt ataatagcaa atgagatggg ggtaaattta
    45481 agaattacgt caggacctgc aatagaaaga gctggagatt tggcagccat acttacgaat
    45541 ttaaatgaaa atgatgtttt atttatagat gagatacata gaatcaatag aagtgttgaa
    45601 gaagttttat atccagcaat ggaggatttt tgcctagata taataatagg aaaagggcca
    45661 tctgcaagaa gcataagact tgaccttcct aaatttacac ttattggagc tactacaaga
    45721 gctggtatgc ttacaaatcc acttagagat agatttggtg ttatttgtaa attggactat
    45781 tatacagttg atgaactttc aaaaatagta cttaggtctt caagcatctt agatgcagag
    45841 atacagtcta atggagcatt agaacttgca aaacgttcaa gagggactcc aaggatagca
    45901 aatagattac taaaaagagt tagagatttt gcacaagtta gagctgatgg aaaaataact
    45961 gataaggtgg caaaagatgc tctggaactt ttaggagtcg atagtttggg tctcgatttt
    46021 gtagatgaga agcttcttat gactataata gaaaaattta gaggaggccc agtgggttta
    46081 gatacattgg cagcttctat cggagaagat agaaatacaa tagaagatgt atatgagcca
    46141 tatttacttc aattaggatt tataaataga ggtcctagag gaagagtagc catgccatta
    46201 gcatatgaac acttaaaaat tccatatcct aataaaaaat aaaaatagat tatacgagta
    46261 tttataaaat aaaatagtta ttaaattaaa atatttctaa aatggctaaa aattcaaaca
    46321 tatccacaaa atggtaatta tatctgtaga tactgtggat aaacacgata aaaattgtgt
    46381 gtattgtatc tatatattgt ggataagaca tgtatatcgt ggaaaaatat ctatatattg
    46441 tggatatggt gtctgttaaa aatagcaatt tcttgataga ttatagtaat attgtggaaa
    46501 ataagttgtt tttttgatat tattgtagct ggagaaattt taagagagga agtttaacat
    46561 tgaaaacaag tgattttaaa tttgacttac cacaggaact tatagctcaa gttcctatag
    46621 aagatagagc tagctcaaga ttgatggtat tagataaaga gacaggtaat attgaacata
    46681 aagtatttag agatataata gaatatttaa atccaggaga ttgtttagta ttaaataata
    46741 ctagagttat accagctaga ttaataggag agaagcttga aactggaggt aaaattgagt
    46801 ttttattatt aaaaagaaca gaggaagata cttggcaggc tttagtaaaa ccaggaaaaa
    46861 gagcaaaagt agggactaaa ttttcttttg gaaatggaaa gctaattgga gaagttgtag
    46921 atttatcaga tgaaggttca agaattataa aattccatta tgatggaatt tttgaagaaa
    46981 tcttggatga acttggaaat atgccactac ctccatatat cactgctaga ttagatgaaa
    47041 aagaaagata ccagactgtt tattcaaagc ataatggttc agcagcagca cctacagcag
    47101 gattacattt tacagaagaa ttgttaaata aaataaaaga aaaaggtgta gatatagcct
    47161 ttgtaactct acatgttggt ttaggaactt ttagaccagt aaaagtagag gatgttttaa
    47221 atcacaagat gcattcagaa tattatatgg ttagccaaga agcagctgac aaaataaata
    47281 gagcgaagga aaatggaaac aatgtaatat gtgttggtac tactagttgt agaactatag
    47341 aatcagcttg taatgaggat ggaaagatga aagaaactag tggatggaca gaaatattta
    47401 tatacccagg ttataaattt aaagttttag ataaacttat tactaatttt catttaccag
    47461 agtctacact aataatgtta gtaagtgcta tttgtggaaa ggataatgtt ttaaatgcat
    47521 ataatgaggc agtaaaagaa agatatagat tcttcagttt tggagatgct atgattataa
    47581 agtagggagg taatggatgc atagtttaca aaaacaaaaa aagaataacc ctatattaaa
    47641 gattgctttt atatttgaac gtgttttagc agtagtagtt ctaatagcag tgtttttagg
    47701 aactatagat gttctaagac ttatgtgggg agcatatata gttgattttc aaaatccagt
    47761 acaatacagt cagcttaatg attttttagc acaaatatta cttttagtaa taggtgttga
    47821 acttgtagta atgctatctc ttcatatacc aggagcattt attgaggcat tactttacgc
    47881 aatagctaga aaaatgttgc tactgcctaa aaatgaaggt atgatagatg ttttaatagg
    47941 agttatagct atagcaggac tatttgctat aaaaaagttt ttagtaacaa aagacaagag
    48001 tgctcttaat ataatgagta ttcatgatga agaagcaatt aaggaacaac agaacaaaga
    48061 agacgaagat aaatctattt agacaataaa ttatatgaat agcttattac aaatacatct
    48121 taagaaataa tgagaaataa atatgattaa ggagaacttt atgtacgcag taagatacga
    48181 attgataaag acttgtaagc agagtggtgc aaggttagga agattacaca ctccacatgg
    48241 gattattgaa acaccaatat tcatgccagt tggaactcaa gcaactgtaa aatctatgac
    48301 accagaagaa ttaaaagaga ttggttcaca aataatactt agtaacacat accatttata
    48361 tatgagacca ggtcatgaac ttataaaaag agctggtggt cttcataagt ttatgaattg
    48421 ggataaacca atacttacag atagtggagg gttccaggta tttagcttag ggcctttaag
    48481 aaagataaaa gaagaaggtg tagaatttag gtcacactta gatggttcaa aacatttttt
    48541 aactccagaa aaagctatgg aaatacaaaa tgcattgggt tcagacataa tgatggcgtt
    48601 tgatgagtgt gcaccatacc catcagatag agaatatgta aaaaattctt tagaaagaac
    48661 aacaagatgg ttaaaaagat gtaaagatgc ccataataat accgacaagc aagctttatt
    48721 tggtataata caaggtggga tgtataaaga cttaagggaa caatcagcaa aagaaataac
    48781 taatattgat ttaccaggat atgctattgg tgggcttagt gttggagaac caaaaccact
    48841 tatgtatgac gtactagagc atacaactcc acttatgcca aaggataaac caagatacct
    48901 aatgggagtt ggtagtccag atgacttagt ggaaggtgtt ataaggggag tagacatgtt
    48961 tgattgtgtc ctacctactc gtatcgctag aaatggaact gcaatgacta gccaaggtaa
    49021 agtagtagtt agaaatgcaa cttatgctga agactttact ccacttgacc ctgaatgtga
    49081 ttgttatgct tgtaaaaact attcaagagc ttatataaga caccttataa aagcaaatga
    49141 aatattgggt gcaagattaa taactactca taatcttcac tttttattaa atttaatgaa
    49201 acaaataaga caagcgataa tggaagatag attacttgat tttagaaatg aattttttgc
    49261 aaaatatgga tatgaaatat aggttttgca ctattaatta taatcatttt aatatataat
    49321 attcaatagt actcaaagat agagaaagta aattgttata taaacattta ttatgattta
    49381 caaaagagta taatttacaa aggagtgaaa aattaatgcc acagcaacaa ataattatga
    49441 gtataggtct atgggtagta gtaatcgcaa tcttttattt cctaatgatt agacctcaaa
    49501 agaaaaaaga caaacaatta aaagaaatga gaagtagcct aagtgtagga gacaaggtca
    49561 ttacaatagg tggaatagta gctaatgtag ctaaagttga agatgatgtt gtaatattag
    49621 aattaggacc aaatagaact aaagttccat ttgaaaaatg ggctatagga actgttaaat
    49681 ctaaaaaaga agaaatagaa gaagactaaa ttagtaattt aaaagccttt tctcgaatat
    49741 atattaattt gagaggaggt ttttttatgg gaaaatctaa ttatattttt aaaggtctag
    49801 gatatgcata tataataact ttggctgttt tattagtgta taacttattt ttgacattta
    49861 cagatattgg tggagataat ataactatgg tctcatcatt tataactact atttctgcag
    49921 ctataggagg gttttacact tcaaaacaca tgaaagaaaa aggacttatg tatgggcttt
    49981 tagtaggact tttgtacata gtatgtattt ttttgactgt gtttttagca caagaaaagt
    50041 ttgtatttga agtagggatg atttataagt tattgctaat atcagcagca ggaggcattg
    50101 gaggcgtatt aggtgtcaac tttaaataga gtttatatta aagtagtttt atgatataat
    50161 caataggaaa caattagaaa tggaggcgtt gaaaatggaa aataaacatg taaaaacttt
    50221 atctcaagct actttaaagc aaagtgctgc aaaaggtgga tgtggagagt gtcaaacttc
    50281 ttgtcaatca gcttgtaaaa cttcttgtac agttgcaaat caagagtgtg aaagatagaa
    50341 aattattgat ttagttgttt gtaagagggt atctcaaagt gattctttta tcattatgag
    50401 gtatcctctt ttattttcaa ttattatata aaaatatata ttctacttat gtaaaattaa
    50461 atttgatttc ttatcgttta attatgcaag aatatctaat catataagag catttatttt
    50521 aaagtatctg ctcttatatt ttatttttta tcaattacat gtattagaat aatttttaat
    50581 tttaaactct aatttatgat gatttttata atatgttata tattttaata tatggagata
    50641 gatattaatt tagtgatata tatttaagta ataagagtaa agcaaaaatt agtacatagt
    50701 agtatatcaa aatggagttt gaatactttt gttagtatat gattgtttag tagaaaatca
    50761 ctataaaata gggatttcta tctttgagca taattataga tagctaagta ggggaagggg
    50821 ttcaagaaga tattattagt gtttgtgtta gtaaattatg taaacacata aaatatattg
    50881 aaaaataata ttatatataa tattatttat atgtgggaaa tacgaatata aaaaataaaa
    50941 aataatattc ggaggacata aatatgttaa gcaacaaaaa gagaagtatg gcaatagtaa
    51001 tggcaggtgc tacagttatg agtgcagcag caccaatatt cgcagacaat actgtgacag
    51061 aaaatgttga taaaaattac acagtaagtg cgaaagattc tgctaaacta atcgaagagg
    51121 ttagaaaagc attagaagtt aagtttgaag atacaaaagc aggagcaaat gtaaatgata
    51181 gagtttacga tataaaagta gacaatgtaa acttaactaa tgcaactcaa ttacaaaata
    51241 aaataaactc tttaacagaa gggcaaagtt taaaagttac tattcaagat aaagggcatc
    51301 aagtgttagg tggaaaagta gttgactata aaattgaaaa ctacaaaact gctcaagaaa
    51361 tagtagatgc agttaatgct tacaatgcaa ctttagcaga agattctgat aacaagttaa
    51421 cagcaactat aaaatctaca aatacagttg aagtaaaaag agcaaaagat tcagcaaatg
    51481 ttattacatt aaatgtagga gaccaacatt tagatttctc aaaagtgata acatcagaag
    51541 aaggtacttt tgaaggttat gaaaagagtt atagtgacat agattcaaaa gaattacata
    51601 cgataacagt taaaaacgca gatttacaag acatatcagc agaagaatta tttgatggaa
    51661 ttagattgac tacattagga agagaaatag ttaataaagt taaaaatgga tatgctttaa
    51721 catttgaaaa tgaagcaatc cttactcaag aacaagaaga tagtgatgat aaagataaac
    51781 cagaaaaatc aagctttgat atagttttaa gcaaggcaaa tgaaaagcca gaaacaataa
    51841 gtgtttcaag taaaaaccat aagttagtta gagacttaca caaagtatta actgatgtaa
    51901 aagatggaaa agaattaaaa gtagaagttt tatctggtga ttcaagattt acaacagcag
    51961 tagaagttag taaagagaga ttcaaagatg gagaagcaga agctataatt ttagttggag
    52021 aagatgctat agttgatgga ttagcatcag caccacttgc ctctcaaaaa aatgcaccaa
    52081 tattattatc taaaaaagat tcactaccat cagaaataga agctgaaata ttaagagtac
    52141 ttggaagtaa tctatcttct aagaaaatat atatagtagg tggagaatct aaagtatcaa
    52201 aagaaactga agaaaaactt tctaaattag gtgtaagtaa agttgagaga gtttctggag
    52261 aagatagatt tgaaacttct ttagaaatag caaaacaatt aaaagataca tttaagactg
    52321 cttttgtagt aggtggaaac ggagaagctg atgctatgag tatatcagct agagctgctc
    52381 aatttggtgc tccaataata gttacaggta acgaattaga tgcaaatgct gaaaaattat
    52441 taaaaggaaa agaattagaa atagtgggtg gagaaaattc tgtatcaaaa gaagttgaag
    52501 acaaattagt tgatatagat ttaaataata aagttgaaag attagctgga gaaaatagaa
    52561 aagatactaa tgctaaagta atcaataagt actatgcagg tgcaactaaa gcatatgtag
    52621 caaaagatgg ttatgtaggt ggaaatggac aattagttga tgcacttaca gcagcaccac
    52681 ttgcagctag ttcaaaggct ccaatagtat taactacaga agaactttct aaatcacaag
    52741 aagaagtagt tgagttaaga cttaagaatg ctactaagtt agtacaaata ggtgaaggaa
    52801 tagctaaaaa cgctattgaa aaaatagcag aaaaaataaa cttatttact aagaactaat
    52861 aagatatagg aattaatatt aaaagtttat ttagataata tatgattata caatgtgtta
    52921 atatgtaaga catagtgtag atattataaa atatacaaat aacaagataa aataataaaa
    52981 ataaggtgtc tcatttagaa ttaaattgag ataccttatt ttattttttg attataatgt
    53041 tgaaaaattc atattgcaaa aattattata aaaagatact tcttataatg attaaacacc
    53101 ttattaacat aaattatttt gaacttataa cttaattaaa taaaataaat tataatgttt
    53161 tgaatttata gagaataaaa acttttggta tattgtttga gttgtatgga taactatggt
    53221 atcatatata aaatatggta acaaaattgt aacttttgat tcaaaataag tatgagtact
    53281 aataaaaaat gtgaaaagta cattgggggt agaaaataat atgaagaata gtaaaaagat
    53341 attagctata ggacttacac tatttttagt aatggtaaat actcctatgg taaatgcgtt
    53401 gacatcagtt gagcaaataa aagggaatga cagatatgag acagcagcaa aaatagcaga
    53461 taagcaaaac tacaatacag caatactaat caattcagat aatagcttag cagatggtct
    53521 aagtgcaagt ggtttagctg gagccttaaa tgcgcctatt ttgatgacaa agcaaaacca
    53581 gattccaaac acaactatgg aaagattaaa caaagcaaag actgtgtata taataggctc
    53641 agaatcaaca ataagtaaaa atgttgagaa tcagttacta tccaaaaaga aggttgtaca
    53701 aagaatattt ggtgaaaata gatttgatac aagcataaaa atagctgaaa aaatcaaaga
    53761 aattaagcca atagataaag taattatagc caatggattt acaggagaag tagatgcgat
    53821 aagtgcatca ccagtagctg ctagagatgg agtacctata atacttacag atggaaatag
    53881 tgtgggattt gacacaacag gtttaaagag ttatgcgctt ggttctagtg aaataatcag
    53941 cgacgaatta gttaagagca caaattctat tagattgggt ggcacagata gatttgaaac
    54001 taataagatg gttatacaag agttttataa aaatagtaaa gaattttatc taagtaaagg
    54061 cttgcaatta acagatgctt tggttgcctc tacaatagca aaaaatgctc ctgtagtttt
    54121 agttgaaaat ggcagtaaca agagtatttt aagtggtgca gacaaattga ctgtactagg
    54181 aggcataaat cagaatgtta tcaagcaatg tataaatcaa gcttcaccaa atcaacaagg
    54241 gttatattac aatccaaatg atagagcatt taaagagaga ataaagggta aagtatatgc
    54301 tcttacaaag cattatagaa aagagaatgg agtaagagcg ttatctgtag caagtagatt
    54361 agagggtcta gcaaatgatt ggtctaattt aatggcaaat aagaagactt tatctcatac
    54421 gataaatgga aaaaattcat attctacttt tttgaaatac ttagattgga gtgagattaa
    54481 acctggatat atagcagttc aaggtgaaaa tataattaaa tataaaattc cagataaacc
    54541 tgtgtataca aatagagatg cagatgatat aggaaacttt atttttaatg agtggaagac
    54601 aaatccagaa gaaggtacta atatgttgca taaagggtat gaaataatgg gatttggtat
    54661 agctataaca ggggataaga atctatatgc tacacatgaa ttttatggaa gatataaaga
    54721 ataataaaat atacacaaaa ttatgcttgt aaggaagcta tataaataat taaattataa
    54781 tggaaaataa catttatatt aataaattaa tataaatgtt atttttttat aatttaattt
    54841 aaaaaaattg tattaaaaag tttagatata gtataaaatg ggtaagaaag tagtgaaaat
    54901 taaatggcaa aattagggaa atctaatgac gcaaaactat agggattaaa gcttttaaag
    54961 ccatatcagc cagttgctaa aaagagtaaa gtctttttat tttataatta agattctctt
    55021 tgagtgtctt tttttattgt ctgaaactta tagtatttaa attcatgaaa aattagatat
    55081 ttattaaggg aggattgtta tttcatgaaa aaggcaatat cttgtgtact agcagtatct
    55141 atgtgtagtg caccactaaa cgtttttgca gaacctatat tagaggggaa actaagggca
    55201 gttgaaaaat cagttacaga aaagttaagg gggagtcttg aagtagattt aaatttttca
    55261 ctgccaataa aaaatagcga gtcagaaagt atgactaata tgcagttacg attaaaagat
    55321 gatagtaaca atagtggaat aataaagctt ggagaaaaag attcaggaac agtaaatgtt
    55381 gggacagata atatagaata tactataaaa aaattatctg caagtagaag tgaaataaaa
    55441 aataaagatg ataatatatc atattataat attgtattta ataatttagc tgttggaaaa
    55501 tacaatgtag aagtctctgg agatggattt aagaacaaag aaattaaaga cattgatata
    55561 tcaagttatt cacaaagagt cttattaagc aatagagcaa gtgtagataa taaaaataaa
    55621 cctttaaatt atgaattatt cttaatgggt gatgtaaatg gagacggtaa agtagataag
    55681 agtgattata ataaggtttt agagaatata gattcaaata aaagagaatt tgatttaaat
    55741 agagatggaa aggtagatat tgttgactta gattatgtac agaaaaattt aggacaaagt
    55801 gaagatgcaa aaagcctaga aagtatagta tctaccaatc ctatagtaga tacaagtaag
    55861 gttgaattaa aaggaaatag tgatgtagat attaatggta atgtagaaaa tttatttagt
    55921 ggaaaaaata atggagttac aatatcttca aaaaatgatg aaatatctga ggaaaaacca
    55981 gcagtaatgg atatagcttt atcagaagca cttaatatgg aagtcgtcaa tataaaagct
    56041 ccagaaggta ctgctccagc aaaaggaata gttgaggtta ctgacaaaga tggtaatgtt
    56101 caacagattc cttatgaaaa caaagaatat atgaaaaact taaaagatga ggagcaacaa
    56161 gaggaagtaa ataacgaaca agaagaagta aataataaag atgaaaatat aaaccagact
    56221 gataataact caaataataa agatgaaaat aatgataaac aacaggaaaa tagcgataaa
    56281 caagaagcaa actctaatac caatcaagat aaaaataatg ataaagaaaa ttcatcaatg
    56341 gataaaccta attcagatga agatactcca aaagaagagg gtaatatcag taaaaataat
    56401 aactctacaa catctacata tagtaagtca acattagaaa catatgcaga tgttcaaaat
    56461 agtgatatag taataaatct tggtaaacaa gtagcagtaa aaaagataac tataaaaata
    56521 acagctacaa cagcaaatga tagaaatctt gcagaaatat caaaagttga atttttaaac
    56581 aatgtatata aagaaatacc aaagccagag atgaacatac ctaaaataaa taaaatatcg
    56641 actagcactg ctgttggaaa tgaaaaagta tctttttatt ggaataatga agtaaatgta
    56701 tcagcatacg aacttatact agataaaatt gatagtaagg gaaaagtatt atctactaaa
    56761 aaattacaaa ctagtaaaaa tacaatagaa gttagagata tagaagcata tggactatat
    56821 agagttagca tacaatcttt aaatggagat tggtctagtg gttataaaga tgcaacacca
    56881 gaaaacttag atggagtacc agaaaatgta gattcaaact ataaacctat acaatttagc
    56941 ccagatagta tattagaatt tcaagttgtt ccagacacaa aaccagaacc accagaaggt
    57001 ataaatgtta aaggtaaatt taaatctctt gatgtaagct ggaaaaatca taaacaagct
    57061 aaagactttg acttgtacta taaagaaaaa ggctctaatg ggtcttggat aaaatacaat
    57121 gataagctta ttcgtgggac aagttcaaag atagaaggtc ttaaagataa tacaacatat
    57181 gaagttagaa tgacagctac taaccacttg ggaactagtg gaatgtctaa aacatatata
    57241 ggtacaactg aaagcatgga tgcaccaaca acacctaact atagattaat taatactcct
    57301 aaagagaatg gtggatttgg aataccaaca aatcacattg tagatgttac ttatccagca
    57361 ggatatgaca aaagtgaata tagtgataaa aatccatttg ataaattcaa tgtagtagat
    57421 ggggacttta caacacattg gacattccca acatataatg cagctgaggg aacgaataga
    57481 ggaccaataa taacttttga taaatcttat actatggata cttttatggc tacacctcgt
    57541 tttgatgttt ctgataagac aataaatgac tttgaggtac gatattggga tgaaaatggt
    57601 caattacaca atctggggga tgttcctttt gaaacaaaga cagaccctgt aaataataat
    57661 aagtatgtaa tggttagatt aaaagaacca ataactgcta ccaagataca agtaagtgtt
    57721 tgctcatcct attcatataa gtctaatata tcagaactta agttttatga gtatgacagt
    57781 atagaagatg atgtaagaaa tctatttatg gatgacctac aagttgaatt aaaagaagat
    57841 gtaactcaag aaaaaataac tgaattaaaa gatagattaa atactccaga taaagctagt
    57901 ggagaatatc atccatataa gacagttatt gagagagaat taaaattagc tcaagactta
    57961 tataatgata gagccacact tactgatgta actactgtaa atcaagaaat aaataaatta
    58021 ggaaaatata aagataaaaa cggacagtat actgtaaatt ccaataattt aggtatgcaa
    58081 aatgactggc aggcattagg agtagctgct agagcaggag atgaaatcac agtatatgtt
    58141 ggaagtaaaa gtggaaaaac tcctaagttg atatatacac agtactatgg agaatctggt
    58201 gcatataaga gtggagaaat aaatcttaaa actggaaaaa atgtaattca attaagcaaa
    58261 cttcatagtt tagatataga atgtggagga agtttataca taagatatgc tgaagatact
    58321 ccaagtggag gagatataaa agtacgtgta gcaggagcta ctaagatacc acatcttaat
    58381 ctaaatggaa caataaatga taagagtcct gcgggagttt ctgaatctaa gaaaaagata
    58441 aaagcatata tagaagaatt agctaaatat aaagatgctg taaaaggaga accatattat
    58501 ccaggaacaa atgttggtaa ttcatatgga tattcagaaa aaactggtgt gttaaacact
    58561 acagatattg aaagtgataa agtaacatta aatgttcctg caacagctgt atatcaaggg
    58621 atatcaaaag gaaatgctga tttaaataca caagtagata gattatataa tagtatgctt
    58681 gcatgggaac aaataatgga tttagtttac tcagaaagag gcgtatttaa aacacaagat
    58741 ttagatggta atggaactgt agatgataat gaatttaact taactaaaaa tgatatggct
    58801 ccaaaatctc gtatgaacat aaaataccaa agaatgttta ttggagcatt tatgtatgct
    58861 tctggattac atgtaggagt agaatatggt tcagttccag ggcttatgaa tggagtacct
    58921 ttccaaatag atgatagtgg aaaagctaca ggaggaaact tatttggatg gggaataggt
    58981 catgagatag gacatgttac agatattgga aagatgacat atagcgaaac tagtaacaat
    59041 gtacttgctt tacttgccca gacatttgat gataagacac attcaagact tgaaggttca
    59101 acaatggata agatatatga acatgtaact tcaaatagct taggtatacc aagcaatgta
    59161 tttgaaaggc ttggaatgtt atggcaatta catctagctt atgatgatga ttttacgggt
    59221 tcaatgttaa agaataactc agatgttgat ttaagtaatg acacattcta tgcaaagatt
    59281 tcaagaaaat acagagcact ttcaagcagt gacccaatta atagtttacc aaaagaccaa
    59341 atgctagtag caatggcatc aagtgttgtt gaaaaagatt taagagatta ctttaaggca
    59401 tggggagtag aaattacacc agaattaaac agtataatgg atagtaagaa ctacgaaaaa
    59461 gaatcaagaa agatacaata tgtaaatgac gaagctagaa gaaagacttt aaatgaaaat
    59521 atagctagta tggcaaaaga tactaaagta agtgctagtt tttctgatgg aatacaaagt
    59581 ggttctctag ttaaatctaa taaaatatct atagacctag atgtagataa ggataaagat
    59641 aagatattag gatacgaaat aataagaagt gatggaaatt atttagaggg tgaaaatgga
    59701 acacaggtaa aatacagaac agttggattt gtggatgcaa aaggaaatag taaggctaaa
    59761 tttactgata atatatctcc tcttaataac agagcattta catataaggt agttgcatat
    59821 gattatcatc taaatccaac agaagaattt gaagttggta ctgtaaaatt atcagatgaa
    59881 gggaaaataa ataaatcagc atggtcattc ataacaaata ctgtttctga tggtgatgtt
    59941 agaactgaaa atgactcaca tgggccatta caaaatcctg aaattgataa tataaaagat
    60001 aatgatgcaa gtactacata taaaggaaag ataataagta aagcagagtg gaacaaagac
    60061 cctcaaaaag accctgatat aaatgtagaa gaaaatccat atataatagt agacatgaaa
    60121 gaaacattac ctatagtagg actaaaatat acaaaaccaa aaacagaaac tagaaagttc
    60181 tcattaaaag gattatttaa ctttagaaag gatactagca caacatacaa tcctttaact
    60241 aattacaaga tacaagtaag taatgataaa aagaactggg aagatgtaag tcaaggaact
    60301 tttgaatatg gacaagattt agttggtgga ggaaaagacc aagataatga agctagagtt
    60361 acatttaata aagatggtaa actttggaca taccaagcta gatatgtaaa actaatctca
    60421 aataataagt ctaatataga agttgcagaa ttagatataa taggacctcc aggtgataat
    60481 atagaaattg gcacaatgaa taatgcagac caaactcgta ctaatggaat tggaaagtta
    60541 gcagaagatt atgtatatca aagtgatgac tctaacacaa gtgaagatga aacaggtaag
    60601 attccagcag gttcaatagt tattacaggt gaatacagtg gaaatccagc atttaattta
    60661 ccactactta tagataaaaa caataagact atatctggag aagcactttt atttgcagaa
    60721 gttccagaaa aaggtgaatt aggtgaaatc agtaaaggta catgggttta ctatatgcca
    60781 aaagaaaact ttgattcttt aagtgataag gttaaggctg aactatatag atacaatgac
    60841 cttcaaggag atactccagt aggtcaaaga tttgtaagtg atacaatgta tgtacctgta
    60901 ggagctaaga attatgatga gttaaagaca ataagtctta ctgatagtaa tagtaaagct
    60961 agaaaagcta caagaaatgc tattgatgtc agcaataaga aggttgtaac tgtaagcaat
    61021 aaagtaaagg gtaatattgt tagagataaa tagtaggtgg aactctaaaa acgtaaaaat
    61081 actaatacta acatggtata tctaatatga ttaggtactg gaatagtttt aaaatagtag
    61141 atattaaaag taaagtatat aaatgtaact ataagtttag ggtaatttat aaattaaata
    61201 taaaagctag gtggataagt aaatttatcc acttagttaa tgacagataa ggacgggtgt
    61261 taatgagtaa aagaaaatct tttataagaa ctatagcagt atcaactatg gcagtagctg
    61321 taactggtag tgctacatgt gcatatgcag ctccagtttt acaaggaaca aaaacgtatg
    61381 agaaagtaaa tactatagat atatctgtgg actcagtaga aaatatagta tattcatttc
    61441 aagccagtat aaaagtacaa ggtgaggttg aagtagtaga taatgagcag aaagaaaaga
    61501 ttacttggtc tgataatata aaatctcaga taaaaagtgg aaatgcaaat gctacttgta
    61561 gagcagaata caacaaatca agtaatacaa ctacattaga tatatatgtt acatcaaatg
    61621 aagatttact agacggaaat agattgaata taggaagaat atctataaaa aaatctggca
    61681 gtaacttaaa tgccgactat aaagtttttg gaaaaggaac aagcgataaa ccagccttaa
    61741 aaattgtaac atataacaat aaaacagtgg attatgagaa tataaactct gatgaaggat
    61801 taatatttac ccttattaat gagagtgaag taaaaccaat tggtggaact ggttctagta
    61861 aaaatgaccc tgaaaagtat aaggtagaga aaagtgaagc acttgaatat ttattaaaca
    61921 atattaggat aaactattct attgttagta aagaaacaca agaaagtggt ttaaatgtaa
    61981 tattaaaact tggattagca caaaaaacaa ctaagggaag aaaagctaca ataaacaaat
    62041 atgttgaagt tacacttcca aaaagtttag aatacatagt tgaaaatgaa ttatcaaaac
    62101 cggacgaatt accaccagat aatggcaatg gtggaaataa tggtggagga agtaattcag
    62161 gcggttcgtc tagtggtgga agctctggag gaggaaattc aagtgattct acatctaatg
    62221 tcacagtcaa aaaattaaaa ggtgctgata gatttgaaac agctatcaaa atatctcaaa
    62281 gtggttggac aaaatcagat acagttgtaa tagtaaatgg agaagataaa agtatggtgg
    62341 atgggcttac agctacacca cttgctagtg taaaaaactc accgattctt ttatcatcaa
    62401 atgaaaagct tcctcaaaaa actgtagaag aattgaaaag gctaaatcca tcaaaagtaa
    62461 ttgtgatagg tggaaacaac tcaatgccaa attcagttgt tgaagctatc aaagctgtaa
    62521 attcaaaaat atcagtacaa agaataggtg gagatacaag atatcaaacc tctattaata
    62581 tagcaaaaga aatagataag acgaataatg taagcaagtt gtatatagga gcaggaaatg
    62641 gagaagctga ttcattatca atagcatcac tggctggtaa agaaaaaact ccaatagtac
    62701 ttacacaaaa agatggtgta gatagtgaaa ctgaacaatt tattaaatca aataaggtgt
    62761 caaatatata ctttattggt ggaatagaaa aaatatctaa caaggctatt gaacaagttg
    62821 gaaaaatagc aaacagagat atatcaaaaa atagggtggc aggtcaaact agacaagaga
    62881 cgaatgccaa agtaatagat aaattctact ctcaatctaa actagatgga gttgtagttg
    62941 caaatcaaga caaacttata gatgctttag cagttggacc attagcagct aaaaacaatt
    63001 caccagttat acttgctaca aatacgttag ataaatcaca agaatcgtca ttaaaaggta
    63061 aaaattcatc aaagttgttt gaagtaggtg gaggaatagc ctcatctgta atagataaga
    63121 ttaagagttt aattgaaaaa taaatattaa gtaaatagaa agtaagaatg tatttagata
    63181 taaagttata tatttaaatg cattcttatt ttattttcat catcttagca atttaataat
    63241 attgaggtta aaatgtataa taatttgagc tatattaagt ttaattttaa ataaagcaga
    63301 tatcttttat atatataaat ataaattcaa ttttgaatat gttcaaaaag aagttaaaaa
    63361 taatttttta aatttaataa aataaaacac taatatatag acgagatata ttcatatcat
    63421 atatactcta taatatatgg aaaataaaga gaaaataaat ggaaaataat cacaatataa
    63481 atataaaata taaaaatcat cagggggata tgaaaatgaa caaaaaaata ttatcattag
    63541 gtctagcagt atcattaatc ttagtaaact tcaaaagtgt aaatgcatca tcagtagtag
    63601 aaaaaatata cggtaaagat agatatgaaa cagcagcaaa gatagctgat agacagactt
    63661 atgaaacagt aattttagta aatacagaaa aatcacttgc agatggatta agtgcaagtg
    63721 gattatcggg ggctacaaaa gctccaatac tatttacaca acaaaataag ataccagcag
    63781 acacaaatag atgtctaaaa aacatcaaaa aagcatatat aataggtaca gaagatacta
    63841 taagtaaatc agtagaaaaa gaactagatt ctaaaaatat acaagtcaaa agaattggtg
    63901 gagaagatag actaaaaaca agctatttaa tagctaaaga aatagcaact ataaaaaaag
    63961 tggataaagt actattaact aatgcatata gtggagaagc agacgcaatg agtgtatcat
    64021 cagtagctac tagagatgga gccccaatca tacttacaga tggaaagagt gtgccttttg
    64081 atgtaaaaaa tattcaatca tattgtataa gttcagagga gataatgagt aatcctctag
    64141 ttaaaaatac aaactcagta agaatagaag gaactgaccg atttgaaact aacaaaaacg
    64201 taatagacta cttttttaat agtgcagatg gattctatgt atcagatgga taccaattag
    64261 tagatgcaat agcagctgca ccacttacta aaaactctcc aatggtacta gtaaatgatg
    64321 gaagcgataa aactgtatta gaaggagcta agaatataaa ctctgtaggt gaaatgaatg
    64381 agaaggtaat acaacaatgt ataaatgctt caaagtcaaa tggacaaccc ccaacaatta
    64441 caattggaag tacagaggta tataagggtg aaaagtttga cactggcaag ttaaatatag
    64501 tggctaaaga taacacgggg aaggcattac caatagaagt tgatgggttt atagatacaa
    64561 atagagtagg tacatacata ttgacattaa aagctacaga cgaatgggga aaaagtacag
    64621 gaaaaagagt agaaataaaa gtgttggatg acaaatctca tgattacaac agcccagaat
    64681 ttaaaaaaat ggtatctact gaaatgtata acttaatcaa ttcctataga aaagaaaaag
    64741 gcaaagagcc tttggtagta tctagtaagc tagaaggtat ggcaaatgca tggtctaagt
    64801 atatgatgga taaaaaagta tttgcacatt atatagatgg aaaaaatgct ccacaagtat
    64861 tttctgagtt tggaatgaga agtgaggaaa atatagcata tatttatata gattctaaga
    64921 acgttcaaac tacacaagat gcaaaagact tggcaaaggc tatatttgaa gtgtggaaga
    64981 agtctccaga gtacaatgca aatatgctta gtgatgagtt ttatagtact ggatttgggc
    65041 tttatatatt atctgatggt caagtgcatg ctactcagga gtttttaaat ggcaatgaag
    65101 gtatcttgta aaaaattcca taaatcttgt ttttttgtta atttactgat attataaaat
    65161 gaaaatcaca tctaaagtac tttttgtaat ctgttttgtt attgctttac aggttatggt
    65221 attttgggtg ttttttgttt tagtagttta taaattttga gggaatcact actgaggatg
    65281 taatttatga ttagctgaat tatataaaaa aattagtagg aggagtttga tgaaggtaaa
    65341 taagagagta ttatcaatag gattgacaat atcattaata atggcaggag caccaaatat
    65401 caatgcactt tcgagcatag aaaagataca agggaaagat agatatgaga cttctgcatt
    65461 gatagcagat aaacaaatat atgatacagt catattagta aataccgata attctatagt
    65521 agatggatta agtgcaagtg gattatctgg agttgtaaaa gctcctataa tgttggtgca
    65581 aagagataag ataccaacag atgttgaaaa aagactaaag gatgttaaga atgcttatgt
    65641 tataggtaca gaggatacaa taggtaaatc tgtagaaaat caacttaaga ataaagggat
    65701 tgaagttaaa agaattggtg gggaagatag aataaagact agctatctta tagctaagga
    65761 gatttcagct attaaaccag taaatgatgg tgataaggtt tttcttgtaa atggatacac
    65821 aggtgaggct gatgcaatga gtgtatcttc tgtagctgct agagatggag ttcctgttat
    65881 acttactgat ggaaagagta taccatttaa ggttgatggc gttcaatgtt attctcttgg
    65941 ctcagaggag ataatgagta atgaacttgt gagtaagact aattctgtta ggattgctgg
    66001 taaggatagg tttgagacta ataagaaggt tatacaacgc ttttataaag gaacaaagaa
    66061 gttttatgtt tctcaagggt ataagttagt tgatgctgtg gctggttctc cgttggctaa
    66121 ggacaaacct atagtacttg ttaatgatgg aagtgataag agtgtactta gaggtgctga
    66181 tgaagttact tctttaggtg gaatggataa gaaggttgtt gaccaatgta ttagttctgc
    66241 atctgataaa aatacaatgc ctacaatcac tgctaatgat gtagaaattt ctgtagggga
    66301 taagtttgat aatagtatgt tgaatatagt tgccactgat tattatggaa ataatttgaa
    66361 gcctaatatt gagggaactg tggataccag taaggcagga acgtatgttt tgaatataag
    66421 tgcttttgat aattttgggc aaaagtgtga gattaatgta aatgtcaaag taattataaa
    66481 cacaagtaca aaagacccta atagttatga gtttaaggct atggtatcta atgaaatata
    66541 caatctagtt aattcttata gagatgaaaa aggtaaaaag cctttgaaag aattgaaatc
    66601 tttgactgga atggcaaatg catggtctaa gtacatgtat gaaaaggaaa tatttgctca
    66661 tgaaattaat gggaaaaatg cagctgaggt attttctggt tttggaatga gaagtggtga
    66721 aaatattgca tatctgccta tgaatactca atctatatat ggagacaaag aagcaaaaga
    66781 gattgctaat tctatctttg atttatggaa aaagtcttca aaatataatg ataatctatt
    66841 aaaaagtgaa ttttacagtt tcggatttgg tatgtatgta tcatcaaata gtgaagtaca
    66901 tgctacaatg gaatttttaa atagttaatt taaaattgaa acgataattt aaaaatgaaa
    66961 ataattttaa aaaataaaat tttagggaaa aaagaagaaa aaagttggaa aaaacttcta
    67021 aaaattttgt ataacttatt gaaaatttat tttagatagt ctatcataga gatgtgagaa
    67081 atatttggat taatatgaac atgaaatttt aatgtacata ataagagatg taatttaata
    67141 taatgttggg aggaattttt aaatgaaaaa aagaaattta gcaatggcta tggcagctgt
    67201 tactgtagta ggttctgctg ctccagtttt tgcagcagct tcagatgtaa tatcactaca
    67261 agatggtaca aatgataagt atacagtatc aaatactaaa gctagtgact tagtaaagga
    67321 tattttagca gcacaaaact taacaacagg tgcagttatt ttgaacaaag atacaaaagt
    67381 tactttctat gatgcaaatg agaaagattc ttcaactcca actggagata aaaaagttta
    67441 ttcagaacaa attttaacta cagctaatgg aaatgaagat tatgtaaaga caactttaaa
    67501 aaatttagat gcaggagaat atgctattat agatttaact tataataatg ctaaaactgt
    67561 tgaaattaaa gtagtagcag ctagtgaaaa aacagtagtt gtatctagtg atgcgaaaaa
    67621 tagtgcaaaa gatatagctg aaaaatatgt gtttgaagac aaagacttag aaaatgcact
    67681 aaaaactata aatgcctcag atttcagtaa aactgatagt tactatcaag tagttcttta
    67741 tccaaaagga aagagattac aaggtttctc aacttataga gctacaaatt ataatgaagg
    67801 aactgcatat ggtaatacac cagtaatatt aactctaaaa tctactagta agagtaattt
    67861 aaagactgca gtagaagagt tacaaaaatt gaatgctagt tattctaata ctacaacttt
    67921 agctggtgat gacagaatac aaacagctat agagataagt aaagaatatt acaataatga
    67981 tggcgagaaa caagatcatt cagctgatgt taaagagaat gttaaaaatg ttgtattagt
    68041 aggtgcaaat gcactagtag atggattagt tgcggctcct ttagcagcag aaaaagatgc
    68101 tccactatta ttaacttcaa aagataaatt agattcgtca gtaaaatctg aaataaagag
    68161 agttttagac ttaaaaactt caacagaagt aacaggaaaa acagtttata tagctggtgg
    68221 agttaatagt gtatctaaag aagttgtaac agaattagaa tcaatgggat taaaagttga
    68281 aagattctca ggtgatgata gatatgaaac ttctttaaaa atagcagatg aaataggctt
    68341 agataatgat aaggcttatg tagttggtgg aacaggatta gcagatgcca tgagtatagc
    68401 ttcagttgct tctactaaat tagatggtaa tggtgttgta gatagaacaa atggacatgc
    68461 tactccaata gttgttgtag atggaaaagc tgataaaata tctgatgact tagatagttt
    68521 cttaggaagc gctgatgtag atataatagg tggatttgca agtgtatctg aaaagatgga
    68581 agaagctata tcagatgcta ctggtaaagg cgttacaaga gttaaaggcg acgatagaca
    68641 agacactaac tctgaagtta taaaaacata ttatgctaat gatactgaaa tagctaaagc
    68701 tgcagtttta gataaagatt caggtgcttc aagtagtgat gcaggagtat ttaatttcta
    68761 tgtagctaaa gatggatcta caaaagaaga tcaattagtt gatgcattag cagtaggagc
    68821 tgttgctgga tataaacttg ctccagttgt attagctact gattctttat cttctgatca
    68881 atcggttgct ataagcaaag ttgtaggaga aaaatattct aaagatttaa cacaagttgg
    68941 tcaaggaata gctaattcag ttataaacaa aataaaagat ttattagata tgtaataaat
    69001 tttcttgata aaataaagaa ctccttataa aggagttctt ttattgtgtt aaatattcaa
    69061 aaaagcaaaa aggagactag aatagtctcc ttttattgtg agaaatactt aaatataaga
    69121 gatataacta tttatttaag taaacttatt atactatact taaaaaaaaa tgtctactta
    69181 tccataattt taatgtataa tagtatttga gaaacaaata aggaggaaaa ctacaaatga
    69241 cagttttaga tagaattgta gataagtcag atgaattaga aattaaagta cttaattata
    69301 tagttgatga tatagagact ttggaaccaa aaatggaatc tttaagtgat gaagaactaa
    69361 aagatatgac aaatatattt aaagatagat taaaacaagg tgaaacttta gatgacatat
    69421 tgcaagaagc ttttgcagtg gttcgagaag tttctaaaag agtacttgga atgcgtcaat
    69481 acagagttca attaattggg ggtatagtac tacatcaagg aaaaatagca gaaatgagaa
    69541 ctggtgaagg taaaacacta gttggtgttg ctcctatata tttaaatgct ctcttaggga
    69601 aaggcgttca tgtagttact gtcaacgaat atcttgcaca aagagataaa gaaactatgc
    69661 aaccagttta tgaattctta gggttaagtg taggagttat tacgtctgat ttattgccag
    69721 aagatagaaa aaaacaatat aattgtgata taacttatgg tacaaacaat gagtttggat
    69781 ttgattattt aagagataat atggtaacta gaaaatctga aaaagttcaa agagagttat
    69841 attattctat agtggatgaa gtagattcaa ttttgataga tgaagcaaga actccgctta
    69901 taattgctgg tagtggaaaa gaagacacta agttgtatga acttgcaaat gcttttatta
    69961 aaactttaaa agataaagat tatgagatag ataagaaaga aaacactgta tgtctcacac
    70021 acacaggtct aagtaaagca gagtcttttt ttggtataga aaatataact aatatagata
    70081 atatagagat ttaccatcat acaaaccaag cattaagagc acataaacta atggagagag
    70141 atgttgagta tgttgttaag gatgaagaaa tacaaatagt agatgaattt actggtagga
    70201 tattagatgg aagaagatat acagatggtc ttcaccaagc tatagaagca aaagaagggg
    70261 taaagattaa agatgagtct aaaacattag caacagttac ttttcaaaat ttctttagat
    70321 tatatgaaaa gctttcagga atgacaggta ctgcaaaaac agaagaaagc gaatttgaat
    70381 caatttataa gttaaatgtt gttcagatac caacaaataa acctgttata agagctgatt
    70441 tacaagataa agtatttagg acagaagatg caaagtataa tgcagttgta gaagaagtaa
    70501 taaagataaa taaaactaag caaccagtat tagtgggtac tgtttcaata gaaaaatcag
    70561 aaatgctttc aaaactatta aaaaagcgag gaataaagca tgaagttcta aatgcaaaac
    70621 aacatgataa agaagctgaa attatatcaa gggctggaaa attaggttct gttactattg
    70681 caacgaatat ggcaggtaga ggaactgata tagctttagg cgcaggagat aaaattgaag
    70741 aaaaaaaagt aagagatatt ggtggattat atgttatagg tactgaaaga catgaatcaa
    70801 gaagaataga taatcaactt agaggtcgtt ctggacgtca aggagaccca gggacatcta
    70861 gattctttgt tagtttagaa gatgaaatga taaagttata tggtggaaaa ggaattgaaa
    70921 agattttaaa aaggatgaat gctaaagatg aagatgcaat tgagagtaaa tcattatcta
    70981 aagccataga aagagctcaa agaggaatag aaggtaagaa ttttgagcaa agaaaaaatg
    71041 tacttaaata tgatgatact attaatgagc aaagaaaagt tatatatgag gaaagaaata
    71101 gagttttaaa tgatttaaat atatctgaag atatacaaaa aatggttaga gaaataatag
    71161 aagatgcagc taataaatat ttatctaatc aaagagatta ttatggttac tttaaatctc
    71221 tgtacaatga ttttatgcct ccaaatacat tgttgattcc aggggtagat aaaaaaagtg
    71281 tagatgaagt tgtacaacac acatatgaaa tatccaaaag agtttatgat attaaaaaaa
    71341 tggaagttgg tatagacaaa atagaagaat tagaaaagag agttttattg caagtagttg
    71401 atacttattg gatggaccat atagatgcca tggatcaact aagacaatat ataggtctta
    71461 agtcatatgc acaaaaagat ccatttaagg agtatgcttt agaaggatat gatatgtttg
    71521 aagaactaaa tagaaaaata agaacaacaa cagttcaata tttatacaag tttgattaat
    71581 taagaacaca attcaaaata gtttttagaa ttattttgaa ttgtatcaag taataatata
    71641 ggatctaatt atttaactta gaaaaaagaa gctatattta aaataataat tattttaaaa
    71701 tatagcttct ttttgtgtga gaaatacgga a
//
LOCUS       DAEPKC010000008        70869 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.008, whole genome shotgun sequence.
ACCESSION   DAEPKC010000008 DAEPKC010000000
VERSION     DAEPKC010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 70869)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 70869)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..70869
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.008"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..100
                     /gene="rrf"
                     /locus_tag="KR294_000606"
     rRNA            <1..100
                     /gene="rrf"
                     /locus_tag="KR294_000606"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            220..411
                     /locus_tag="KR294_000607"
     CDS             220..411
                     /locus_tag="KR294_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HBH0238723.1"
                     /translation="MKKVALILAIIGALNWGAIGILGTDLIGSIFGGTYEMVSRIIYF
                     IVGLAGLYLIPSLMSDDRE"
     gene            566..1975
                     /locus_tag="KR294_000608"
     CDS             566..1975
                     /locus_tag="KR294_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBH0238724.1"
                     /translation="MFIINELNKIVNEEVISFHMPGHKKGQVYKKLGYKDILKNLYKM
                     DTTEILGTDNLHFPEGIIKNSQKKASRVFKSDYTCYLVNGSSCGIQSAIMSVCSPKSK
                     IITNRDCHQSVINGCILGDIDIEYVPCEISEETNILKGISISNVIDIIDKNLDAKAVL
                     LTYPTYYGMTYDLEYICNYAHSKKMVVIVDEAHGAHLGLSERLPKTALEQGADIVVQS
                     THKTLPAFTQSSMIHIQGDRVDIDKILNMLRITESSSPSYLLLSSLELAVDIYENKGK
                     ELMEELLNNIITFKNKVDSNINIYDTNDKTKIFISSKNMGLTGYELENILRNKYNIQV
                     ELSNYYGVLLICTIGNTAEDFSSLETALNNVVKEDFKFEKLENKKYPVVIPKKILTPR
                     EAFYKTKKSVKIYDSIGKVCGECIVPYPPGISVISPGEVISKEIIDYLMFCHSKGMIV
                     SGLKDVDLNFIQVIDLEDI"
     gene            2106..2795
                     /locus_tag="KR294_000609"
     CDS             2106..2795
                     /locus_tag="KR294_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate kinase"
                     /protein_id="HBH0238725.1"
                     /translation="MKGKLIIIESGSDASGKATQTEILYERLKKEGYMIKKVEYPNYE
                     SPSSALVKMYLKGDFGKNASDVDPYIASTFFTADRYASFKTDWEEFYNEGGIIIADRY
                     TTSNMVHQASKMDICDREEYLNWLADYEFNLFKIPQPDCVIFLDVPIEFSKKLMENRK
                     NKITGEEKKDIHESDIEYLEKSYNNALYIADKYDWKKINCVLDNKLRSIESIHNEIYK
                     IVLDSIKPMER"
     gene            2798..3733
                     /locus_tag="KR294_000610"
     CDS             2798..3733
                     /locus_tag="KR294_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HBH0238726.1"
                     /translation="MYFENIIGQDFAKKYLTNSIKKNKLNNAYMFEGMDGIGKKKFAD
                     ELSKLLLDYENLENSPDYVLIKPDGNSIKIAQIRNLQSDIVIRPHKDYKIYIINNAEK
                     MTVEAQNALLKTLEEPPNYAIIILVTNNKESLLETIKSRCDIIKFSPIPIEDLKRYLI
                     NTGIEEERAQLLAIFSRGSIENALNLSQSSEFSMMREDIQQYIQIMLDKNIVEILNIP
                     NNMEKYRGKIIALLDMMINYFRDIILLKENVNKNMLINVDKLVFIQNMNGKISYSQLS
                     KIIDIIEDAKSKIKSNCNFNISIQVMSLNIYEVIK"
     gene            3730..4623
                     /locus_tag="KR294_000611"
     CDS             3730..4623
                     /locus_tag="KR294_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HBH0238727.1"
                     /translation="MIKIVGIRFKSAGKIYYFDPVDFNIEQDMDVVVETARGLEYGKV
                     VVGPKDMDESELVSPLKPIIRIATEEDKKVYLENKEKAKETFELCQQKIKEHELTMFL
                     IDCEYTFDRNKLIFYFTAEGRIDFRELVKDLAAIFKTRIELRQIGVRDEAKSIGGLGP
                     CGRKLCCSSWLGDFQPVSIKMAKDQSLSLNPTKISGICGRLFCCLKYEHDVYSEAIEK
                     MPVVGALVQSDDGKGKVVEVNPLLEQIKVEFQDKTVKIYTREDIKILREPKKCDGCGG
                     KCKDNDGLDEATLRELKKLED"
     gene            4701..5447
                     /locus_tag="KR294_000612"
     CDS             4701..5447
                     /locus_tag="KR294_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HBH0238728.1"
                     /translation="MQLKDSERIDDLQLKGLKIIQDTNGFCFGIDAVLLANFTKIKKD
                     AKVVDLGTGTGIIPILIAGKSEAKKIIGVEIQEDVYEMATRSIKLNGLEERVEIINED
                     IKYIDKVLDINGYHVVTSNPPYMHIDGIKNPNDKKAISRHEVRCNLEDVIRAASRLVM
                     PRGKFFMIHRPTRLVDIITLGRKYKLEPKVIQFVHPRPQKAPNLVLVQFVKDGRPELK
                     ILDPLYVYGEDGNYTKELKAIYNNKDIGEL"
     gene            5448..6281
                     /gene="rsmI"
                     /locus_tag="KR294_000613"
     CDS             5448..6281
                     /gene="rsmI"
                     /locus_tag="KR294_000613"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HBH0238729.1"
                     /translation="MSGKLYICPTPIGNLEDITYRTLRILKEVDLIAAEDTRHSIKLL
                     NHFEISKPLTSYHEHNKDSKGDYLINKLIDGENIALISDAGMPGISDPGEEIIKQAIQ
                     NNIEIEVLPGATAFVTALVGSGMDTHRFIFEGFLDRDKKVRKAQLEELKEESRTIIFY
                     ESPHRLKDTLKDMLKILGNRNISINRELTKKYQEIIRENIETTIKIFEEKEVRGEFVL
                     IVEGFHGEKSKKENYDGLTDREYVLKLIESGMNKKDAIKIVCKDRKLKKDVVYKQVLD
                     L"
     gene            6304..7008
                     /locus_tag="KR294_000614"
     CDS             6304..7008
                     /locus_tag="KR294_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing protein"
                     /protein_id="HBH0238730.1"
                     /translation="MEIGKIIIESLKREDTHKIFIELDNKHELEKIIPKISCMKSVGE
                     CKYHVVNCFEHSINALKELEIVLNDKDFFPIHLRKHVSNYLKTYIEEGINKLHVLKLG
                     TFLHDIGKPDSMTLDETGRVHFTNHEKIGAQIIDNMGIKLELSTETYRLISKYVRYHM
                     ILLSLYKKNDLSRKELINVFNLVDEDTIGVIMLGYADIVSTVKLLGKSGEVSVLKTYM
                     EYILTNYLYKSNYTHV"
     gene            complement(7196..7624)
                     /locus_tag="KR294_000615"
     CDS             complement(7196..7624)
                     /locus_tag="KR294_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007287587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HBH0238731.1"
                     /translation="MDVTDYRIIEILQDDGRISMKDLGKIVGLTSPAVSERVKRLEES
                     GVIEGYKAIVNPDSLGRVIKAFIHISLPSNGYTEFIESAAKDPRIVECHHITGDDCLL
                     LKVIVKDMYELENVIDTIKKIGSTKTSVILSTPIQAKSIL"
     gene            complement(7661..9091)
                     /locus_tag="KR294_000616"
     CDS             complement(7661..9091)
                     /locus_tag="KR294_000616"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HBH0238732.1"
                     /translation="MRNLTLLTDLYQLTMLNGYFEKNIHEDIVVFDMFFRKNACDGGY
                     TIVCGIDQVVEYIDNLHFSDEDLEYLKNLNLFSDKFLKFLKEFKFTGDIYAVEEGTIM
                     FPNEPLITVKAPLYQAQLIETALLTIVNFQSLIATKASRVCFAAQGDPVFEFGLRRAQ
                     GPDAGIYGARAAVVGGCAGTANVLAGKMFDIPIIGTQAHSWVQKFDNELEAFQAYADV
                     YPDKCLLLVDTYDVLNSGVPNAIKVFKNISEKGYKPMGIRLDSGDLAYLSKEAKKQLD
                     NAGFSDISITASNDLDEYTITSLKAEGATINSWGVGTKLITSFDSPSLGGVYKLAASC
                     EKGVLEPKIKISENPEKINNPGYKKVIRIYNEDNKAEADLIMLHDEVIDESKPLEIFH
                     PTYTWKTKVFTNYKVKELLKPLYIKGRCKYNKKAVLEIKNHVQYELSTIWEQYKRLSK
                     PHIYKVDLSRNLWYLKTQMIDSKKVL"
     gene            9223..9807
                     /locus_tag="KR294_000617"
     CDS             9223..9807
                     /locus_tag="KR294_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore maturation protein A"
                     /protein_id="HBH0238733.1"
                     /translation="MIIIGKIWFYMVSIGIIGSLISKNMGELNKVILSETSKGIEFAI
                     SLAGIMALWMGIMNIAKESGLIEKIGQKLNPIMRRLFPSIPKGHKAMSYIVMNIALNM
                     LGAGNGATAFGLKAMSELQTLNNKKDTATNDMIMFMVINISSIQIIPFTIIKLRMDMG
                     AQNPSEIIFTTLFATIISTAVAIITCKFFQRRYR"
     gene            9823..10344
                     /locus_tag="KR294_000618"
     CDS             9823..10344
                     /locus_tag="KR294_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore maturation protein"
                     /protein_id="HBH0238734.1"
                     /translation="MEIFSNLLIPIIILYIVVYGKYKKIDVYDSFVKGAIDGLKAAWD
                     ILPYIIGIFLAIGIFKTGKGLDMLEWLFTPIANMMSIPKELIGLISVKPLSGSGALGM
                     YSELANRVGIGSLVEKMGATIVGSSETIFYTMAIYYGSLKIKNTRHTLSCAMISHVAG
                     VIAAVFICYVIFV"
     misc_binding    10410..10656
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            10740..12677
                     /gene="metG"
                     /locus_tag="KR294_000619"
     CDS             10740..12677
                     /gene="metG"
                     /locus_tag="KR294_000619"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HBH0238735.1"
                     /translation="MSKPSFYVTTPIYYPSGGLHIGHTYSTVAADTIARFKRFCGYDV
                     KFLTGTDEHGEKIQKKAIEQGMSEIEYLDGMIKDIKALWNTMDISYDDFIRTTEKRHT
                     DIIQKIFTKLYEQGDIYKGEYEGRYCTPCESFWTESQLLEGNKCPDCGRETYLVKEES
                     YFFRLSKYEDRLKELFKDDSFCFPAARKNEMVANFLDKGLEDLSVTRTTFDWGIKVPF
                     DEKHVIYVWVDALCNYITALGYMTDNDEEFKKYWPANVQIVGKEIVRFHTIIWPALLM
                     ALGLEVPKQVFGHGWILFADDKMSKSKGNVVYPEPIIERYGIDTLKYFLLREFAFGQD
                     GSYTHRNFVTRINYDLANDLGNLISRTVAMVEKYNNGIIPTAKVSTNFDADLKEQAVS
                     TRENFEAEMDKMQFHEALESVWKLVRRTNKYIDETMPWALAKDETKKDELDTVLYNLC
                     ESIRIIATLINPIMNETANKIYEHIGIKGQDDITTWESTKTFGLIGENVKVFKGEPLF
                     PRLDVEKEIEELTKMFSGKPPVEEKPLEHKEEITIDDLDKIELRVGKIISCEKHPKAN
                     KLLVSQVKIGPETRQIVSGIAEYYKPEDLVGKEVTVVCNLKPVKLRGVESQGMILAAG
                     DDGDPYVLPFTQGAKDGCEVR"
     gene            12707..13477
                     /locus_tag="KR294_000620"
     CDS             12707..13477
                     /locus_tag="KR294_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HBH0238736.1"
                     /translation="MLFDSHAHLNDESFDEDRDELIGSLKDKGVDLVVNPGADIETSI
                     TAIELAKKYDFIYSAVGVHPHDVSKLDDTAIETLRKLATENEKVVAIGEIGLDYYYDY
                     SPREEQKEWFKKQIELANELKLPIIIHDRDAHGDTFEIIKNTKNPEIGCVLHCYSGNV
                     ELAREYVKMGCYISIPGTVTFKNNKKTREVVREIPLERLFIETDSPYMSPEPHRGKRN
                     NPSQVSFVADKIAQEKGISYEEVCRVTKENAKKFFNIK"
     gene            13814..14245
                     /gene="phnG"
                     /locus_tag="KR294_000621"
     CDS             13814..14245
                     /gene="phnG"
                     /locus_tag="KR294_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnG"
                     /protein_id="HBH0238737.1"
                     /translation="MYTVDSTKILINMNLEKLEKIYSMIKDTSSISIIKEPNLATVMV
                     RANESVKNTTFNLGEILVTECSVKVDESLGYGIVSENNNKKAIYLAVIDAVLHSNNSK
                     FDELKNYINKSVYEENLRYEQEIIDEFSLINKTKVQFNAMD"
     gene            14260..14835
                     /gene="phnH"
                     /locus_tag="KR294_000622"
     CDS             14260..14835
                     /gene="phnH"
                     /locus_tag="KR294_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnH"
                     /protein_id="HBH0238738.1"
                     /translation="MVNYTQEIYRKMLDSASFPGKLNNIDNINIENNTKLLNGAIGIA
                     ITLLDQEVTFYIENYTQKDIKNIRALTMSNQIDYRKSDYIFLDINSEVDILQIKIGSF
                     EYPDESATIVHQVNDLSTYSQTKYIKLDLSGPGIKSKNSIYINGIREEFIERLSSINK
                     DYPIGIDLILVDKKGEIAFIPRSSKLSWEVL"
     gene            14838..15923
                     /locus_tag="KR294_000623"
     CDS             14838..15923
                     /locus_tag="KR294_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-phosphorus lyase complex subunit PhnI"
                     /protein_id="HBH0238739.1"
                     /translation="MAYVAVKGGEEAILQAKNILEFYRVKGDSLPIDVKQIEEQMSYA
                     VDKVMSEGSLYNKELSALAIKQAQGDILEASFYVRALRSTMPRITYSEPINTEEMRIK
                     RRISATFKDIPGGQYLGATRDYENRILNVELLEEDEKKNRHFRDSFINELETVDEIPE
                     FTKISNIFRKENLLQEEVCENKLEEVIDDITRNSLRFPVSRSAKLQALTRGESGVVSG
                     FAYAIVRGFGDEHPYISELRTGNVFIKVKHPIYEDEEIIIGDMLVTECEIVSKASQNK
                     TENSKTNSEDKNKMSLGYGLCMGNNENKAISMAILDKSLEPNSEKLAQDEEFVLLHID
                     GIDSLGFISHFKLPHYVDFKADVERIK"
     gene            15943..16812
                     /locus_tag="KR294_000624"
     CDS             15943..16812
                     /locus_tag="KR294_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-D-ribose 1-methylphosphonate 5-phosphate
                     C-P-lyase PhnJ"
                     /protein_id="HBH0238740.1"
                     /translation="MIYNYGFLDENTKKEIRRKILKAISIPGYQVPFGSRELPIAKGW
                     GTGGLQLTLSLIGKNDVVKVIDQGSDDSTNACNIRSFIASVSNVETTKDTLEATLIQT
                     RHRIPEEKLKSNQILIFQVPIPETLRIVEPSEVETRRMHSEEDYSRMWVYLYEDIVRF
                     NDISIAVEYPCKVNDRYLMNPSPIPRFDIKKLNMSDNLFLFGAGREKRIYAIPPYTKV
                     EPLEFEDYKFEEEKFEGKYCSLCNSTNTFLDEVYDSDTNEKYYSCSDTSYCEKVRLKN
                     NSIDVTIGGTWNE"
     gene            16805..17671
                     /locus_tag="KR294_000625"
     CDS             16805..17671
                     /locus_tag="KR294_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH0238741.1"
                     /translation="MSKINDSKRLENIDKQVLIGRNINLIYGDGCEKCFESTGYESNN
                     ICKYCGSIVACNNVNLELYEGEVLGIVGESGSGKSTLLKILFFQEHANSGEVYISHYN
                     KDTNILELSDQKKRYIKNHFMGIVYQNPHLGLNLDFSSGGNIAEKLLMANLYNVEKIR
                     DRGKELLIKTNIPVERIDHKPKYFSGGMQQRVQIAKALSNNPPILLLDEVTTGLDVSV
                     QAEVLDLIREIQRELKISMIVVSHDFDVIKMLADRTIVMKNGSVIESGLTDQIMEDPQ
                     HPYTQQLINSLL"
     gene            17712..18425
                     /locus_tag="KR294_000626"
     CDS             17712..18425
                     /locus_tag="KR294_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH0238742.1"
                     /translation="MKETILEVNNFSKDFELHALNKTITACSNISFEVSKGEFLGIIG
                     KSGAGKSTILKSIYKTYIPTTGEIIFNSEIYGNVDLAKIGDREMINLRKKEIGYVSQF
                     LKTLPRITAIELVVHSLIESGFEKDCSYDMAKDILNQFEIKENLWDAYPNNFSGGEKL
                     RLNLAQAMVKKPRLLLLDEPTASLDNQSKIYVKEKMLELKSQGTTMIGIFHDIEFMET
                     VIDKTFTMTKGTISESGVA"
     gene            18426..19595
                     /locus_tag="KR294_000627"
     CDS             18426..19595
                     /locus_tag="KR294_000627"
                     /EC_number="3.6.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-D-ribose 1-methylphosphonate
                     5-triphosphate diphosphatase"
                     /protein_id="HBH0238743.1"
                     /translation="MIKLIHNANIVLEDMILENGHLIIEGDTIKKVSNDKIDYAFDFN
                     EIDEIIDAKNLYVIPGIIDIHSDAIEKEIEPRPSTLLPFNMAFYELDKKLPANGITTV
                     YHSISLGDGVGVRSIDNSLKMIKNIDSYKNIDSKSINHKVHLRYEVLYYEGLEKVLEL
                     LDENKIDYLSIMDHSPGQGQYTNPTFYKEYATKVWGVTENYVDTWLDDLVNLHDNLDW
                     NKIANIIGIAKTKNINVASHDDDTLEKMDFIKNIGINVSEFPITLEVAKHSKKLGVLT
                     CLGAPNIVRGKSHNNNLKAMDAILEDCCDIVCSDYLPSAMIKSMCIVAERINNLNKAV
                     SLFTSNPAKAVGIYDERGSIKENKKADLVLVDIDSEYPKVVNTIVNGKTVYKREV"
     gene            19599..20435
                     /locus_tag="KR294_000628"
     CDS             19599..20435
                     /locus_tag="KR294_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HBH0238744.1"
                     /translation="MLTELHCHTSISDNNFTTEEIIKKAAEKNINILAITNHDTLSGL
                     DEALVLGEHYGITIIPGIEISAYDYKNRKRVHILGYNIDLNSQEIKNLCNPMVCDRHK
                     ASVKMVNKIIDLGYKISLEDVKKYSSKTGIFKQHIMKALIDKGYTDNIYSNLYKELFH
                     RGNGKVYVSLKYVDYRDAIKAIKNSGGICVLAHPGQMDNFSAIEEMVKVGLDGIEVYH
                     PSHNKELEKESLSYAKKYNLVVTGGSDYHGFYSQHNYELGSKSLNKEDLFKFRLALGG
                     VL"
     gene            20436..21431
                     /locus_tag="KR294_000629"
     CDS             20436..21431
                     /locus_tag="KR294_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH0238745.1"
                     /translation="MSFLQVKNVGKSYGQVKVLKDISIDIEKGEFICLLGPSGCGKST
                     LLRIIAGLEDKHGGKIIINDKDMTNSPPESRNFGIVFQSYALFPNMNVYKNIAFGLEN
                     KNISKSNIDKKVKEVLEVVELSGYEKKYPSQLSGGQQQRVALARAIALEPDFLLLDEP
                     LSALDAKVRLKLREQIRSLHRKLGITTIMVTHDQEEALCLADKMVVMNRGEIIQVGTP
                     KEVYKNPETPFVADFIGTINFIDDGINKIAIRPEDIKVESNRDSKDKDIKVGEILDIE
                     FRGFNYRITVEYRSKQMKLDVVSKVAEQMKLCIGSKINFKIPKEGIVQYKSEGCA"
     gene            21449..23137
                     /locus_tag="KR294_000630"
     CDS             21449..23137
                     /locus_tag="KR294_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     permease subunit"
                     /protein_id="HBH0238746.1"
                     /translation="MITSKNKRRISDSTIQKYFLIFSVIVLIVFILFPLVSLLKNAFM
                     DTSGNFIGISNFSKYVENPSLIASFKNSIFVSTVSSLISLCLAFIYSYAITRTNIKFK
                     DFFKTMGMFPLFAPTMLYGISLIYLFGNKGIFTTMGLEVPLYGPLGIIISQILFTFPQ
                     AFLILSVALSMADYRLYEAADSLGASEFKKFCKITIPGIKYSLLSSFFVSFILAFTDF
                     GAAKVVGGNYNVLATDIYKQVVGQFNIPMGATVSMVMLIPVLIAFTLDKMASKKQGMT
                     ITAKSMPYKIKENKFRDRVFLIVCSFITLLIFILIFVSVIGSVIKLWPYNLSFTMEHY
                     TFKGILGSGIKTYLSSLKISTLTAIFGTIFVFFSAYMIEKVDKFPKLRQTAYLLSMIP
                     MALPGLVLGISYITFFNSASNPLNFLYGSTAILVIVNVVHFYSVCFITSNSSLKMLDK
                     EYELVAKSINIPFYKVFFNITVPMSITSILEIVVYYFVNSMVTVSALIFLYTPQTQTA
                     SISILKLDEIGYIGTSAAMAVLVLLTNIIVRLLYEFVTKKLKNNTQKWQQKDVA"
     gene            23149..24216
                     /locus_tag="KR294_000631"
     CDS             23149..24216
                     /locus_tag="KR294_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HBH0238747.1"
                     /translation="MKFKKLVSLGVLSTLLLSVITGCSTDSSGSDSKSDSKTKGDLTV
                     YTAIEEDSIEPYLATFKEKYPDIKLNIVRASTGDITARLLAEKDNPQADVVWGVAATS
                     LLVADDQGMLEPYAPKGSEEIESAFKDDKEVPSWVGIDAWMTGITVNTKELSDKNIPV
                     PSSYEDLIKPEYKGLISMPNPSSSGTGYLTVSALIQIMGEEKAWQYMDKLHENIGVYT
                     QSGSAPATSAASGEYPIGISFGYRGIKLKEEGYPVEVVFPKEGSGWDIEANALVKKDN
                     IKEASKVFLDWAISKDVMNEYSKNYAVTTISTGNPIPEGFPKKPLEQMIDNDLKSAAK
                     NREDILNKWISKYDGKTEKES"
     gene            24653..25648
                     /locus_tag="KR294_000632"
     CDS             24653..25648
                     /locus_tag="KR294_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH0238748.1"
                     /translation="MSFLQVKNVGKSYGQVKVLKDISIDIEKGEFICLLGPSGCGKST
                     LLRIIAGLEDKHDGKIIINDKDMTNSPPESRNFGIVFQSYALFPNMNVYKNIAFGLEN
                     KNISKSDIDKKVRDILEVVELSGYDKKYPSQLSGGQQQRVALARAIALEPDFLLLDEP
                     LSALDAKVRLKLREQIKSLHRKLGITTIMVTHDQEEALCLADKMVVMNNGEVIQIGTP
                     KEVYKSPKTPFVADFIGTINFIDDDVNMIAIRPEDIKVEFNRDFKEIDVKVGEILDIE
                     FRGFNYRITVEYCSKQIKLDVVSKVVEQMKLCVGSKINFKIPKERTIQYKSEGCA"
     gene            25666..27354
                     /locus_tag="KR294_000633"
     CDS             25666..27354
                     /locus_tag="KR294_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     permease subunit"
                     /protein_id="HBH0238749.1"
                     /translation="MITIKNKRRISDSKIQKCFLVFLVIALVVFILFPLISLLKNAFM
                     DTSGSFVGISNFSKYIENPTLIASFKNSIFVSTISSLISLCLAFIYSYAITRTNIRFK
                     NFFKTMGIFPLFAPAMLYGISLIYLFGNKGIFTIIGIEVPLYGPLGIIICQILFTFPQ
                     AFLILSVALSMADYRLYEAADSLGASEFKKFFKITIPGIKYSLVSSFFVSFILAFTDF
                     GAAKIVGGNYNVLATDIYKQVVGQFNIPMGATVSMVMLIPVLIAFTVDKIASKKQGMT
                     ITAKSMPYKIKENKFRDRVFLIACSFITLLIFILIFVSVIGSVIKLWPYDLSFTMEHY
                     TFKGISGNGIKTYLSSLKISILTAIFGTIFVFFSAYMIEKVDKFPRLRQISYFLSMIP
                     MALPGLALGISYITFFNSASNPLNFLYGSTTIMVIANIVHFYSVCFITSNSSLKMLDR
                     EYELVAKSINIPFYKVFFYVTLPMSITSILEVAVYYFVNSMVTVSALIFLYIPQTQTA
                     SISILKLEEIGYIGPSAAMAVLVFLTNIIVKLLYELTTKKLKTKTQKWQQKEVA"
     gene            27366..28433
                     /locus_tag="KR294_000634"
     CDS             27366..28433
                     /locus_tag="KR294_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HBH0238750.1"
                     /translation="MKFRKLVSLGILSTLLLSVITGCNNASSGSNLKSNNKIKGELTV
                     YTAIEEDSIDTYLTTFKEKYPDIKLNVLRLSVGDITARLLAEKDNPKADVLWGVAATS
                     LIILDDKEMLEPYAPKGFDKVNPVFKDDKKVPSWVGIDAWMTGITVNTKELSDKNIPV
                     PSSYEDLIKPEYKGLISMPNPASSGTGYLTVSELIQIMGEEKAWQYMDKLHKNIGVYT
                     QSGSAPAILAASGEYPIGISFGNRGIKLKGEGYPVEVVFPKEGSGWEIESNALVKKDN
                     IKEAAKVFLDWAISKDAMNEYSKNFAVTTIDTGNPVPEGFPKNPLEQMIDNDLKSAAR
                     NREAILNKWIEKYDGKTEKES"
     gene            28625..29155
                     /gene="rnmV"
                     /locus_tag="KR294_000635"
     CDS             28625..29155
                     /gene="rnmV"
                     /locus_tag="KR294_000635"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HBH0238751.1"
                     /translation="MIKEIIVVEGRDDVTAVKRAIDAELITTGGFGFPKGVMERIKAA
                     NERRGVIIFTDPDFAGEKIRKKIASEVPGCKHAFLPREEAKKDGDIGIENATPQSIIA
                     ALNKVRTENTEKRYEFKQVDLIRNGLIGNEEASLRRDALGKILGIGYGNAKQFLNRLN
                     NYGVEREEFIDALKQI"
     gene            29326..30195
                     /gene="rsmA"
                     /locus_tag="KR294_000636"
     CDS             29326..30195
                     /gene="rsmA"
                     /locus_tag="KR294_000636"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HBH0238752.1"
                     /translation="MDRLSSHNATKEVVQKYNFKFSKSLGQNFLIDSNIIDKILSGAR
                     ITRGDNIIEVGPGIGTLTREMGKIAEKVVAIEIDRNLIPILKDTLSDLDNTEVVNQDI
                     LKVDIQELVKDKLNGGPVKLVANLPYYITTPIVMKFLEEDIPVTDIVVMVQKEVADRM
                     NAIPGTKDYGALSIAVQYYCDTEIVAKAPRHMFIPQPNVDSTVIGLHVRDKRKYDVHN
                     EDIFFKTVKASFGQRRKTLLNSLGGLGFLNKDEIREILKEANIDEKRRGETLSIEEFS
                     VLSNIINTKVSSK"
     gene            30261..31526
                     /locus_tag="KR294_000637"
     CDS             30261..31526
                     /locus_tag="KR294_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0238753.1"
                     /translation="MGSKRKFKRDYIILEAKDINFRYKERVLPKAFAKVEVNDEKAII
                     ALYVENLKYVKDGYKAVAIKDDHGLIDLGNIILNEQGRGEFVLDLEDYDDEIKGIALL
                     YERNIPLIGFKGNKLENYEDILFQEVEEEEYEEYEELEEEDEEIEDNEESDRDEGSEE
                     EYIIEEYDEDEYEDYWEDDEDIEEGELKARTEVEDSSDEEIEEFNNYKEIENYNRVKV
                     QEEYIDIEYDEEEEEEEEVFEVNREEDRFVSSKPTKSKKVQKDQNNIEKIKRANGVSQ
                     GESGNKQTSTLLMPRQIKKGLKLFKEVKPFVTDYIDKTRWWKIEINPTTLCGYTMPYL
                     GYLNVLNYTMYSDAVLHSYKYRHYLFGVQYDEYNKRKHYIYAIPGNRNEQPDNGSTGF
                     LRYQACDNRTNSLGYWLCFIDSRQRNIVR"
     gene            31677..32792
                     /locus_tag="KR294_000638"
     CDS             31677..32792
                     /locus_tag="KR294_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HBH0238754.1"
                     /translation="MINEQRILNEFLELVQIDSLSLKEGNVAKVLVKKLEEIGCSVVI
                     DNAGEKANGETGNIIATLKGNKEGKKILFSSHMDTVTPGIGVKPIVDEANGIIKSDGT
                     TILGSDDKAGIAAILEGLRYINENNIEHTDIQVVFSICEECGLVGAKNLDYGKIDSEY
                     AFILDSGGSPGEIIVKAPAQDVINVKILGKTAHAGLEPEAGISAIMVAARAIENMNLL
                     RIDEETTANIGIINGGTATNIVTGEVNIIAEARSLKENKLDVQTKHMVETFEKAAKDF
                     GAQIEIDVNRAYTPIDVSEDSEIIKLAKKAFSNLGIEGHTESTGGGSDTNILSKNGIE
                     AITLGIGMKNAHTLSEHIAIKDLYDSAKMVVEIIKEA"
     gene            32978..33874
                     /locus_tag="KR294_000639"
     CDS             32978..33874
                     /locus_tag="KR294_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBH0238755.1"
                     /translation="METRYEEANKITIQSILWNVVLTIIKVIAGVIGNSSAMIADGLH
                     SASDIISSIGVLIGNYVSSRPGDREHNYGHEKAETLVSFVLSILLIFVSITIGIEAIK
                     SLFNLDALSVPSILPLVVSVISILIKEYQYRITIKVAKKINSPALKADAWHHRSDALS
                     SVAAFIGIGGSILGFKPLDPIASVVVAIFVAKVGISILISSVNELMDVSVDEEEIKEL
                     KFIVADTEGVKNLGDIKTRKHGAMAYVDLTICVDENLTVKQGHDIATKLEKHIIKHME
                     FVKGITVHVEPCTNCQGNKCNN"
     gene            33944..34741
                     /locus_tag="KR294_000640"
     CDS             33944..34741
                     /locus_tag="KR294_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0238756.1"
                     /translation="MSKKRKLKKKAAILIGVVVFFIIYFISFRIGINMEKDKSEVPKK
                     VEKEEEDNRSLRTQIKEKKKVYISDKNIENIKIEEDMWDEIKLFFSDFKKVRNTTSSY
                     EAVYEGYSDDGVKFSTDLNFFRVYTVNKEEYYKVPVSSKDAFKKLLDESIYTSFDLLS
                     HYKDWKEVTITHGKEIKKVHRWKFDDLAHKMISKRVVGKVQPEKSKERSDYNFTINIK
                     GDNFDVKVDTMGKDYVKVTSKKNVSYYEVHTSLFDYLKNEIFEIGKK"
     gene            complement(34797..36149)
                     /locus_tag="KR294_000641"
     CDS             complement(34797..36149)
                     /locus_tag="KR294_000641"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HBH0238757.1"
                     /translation="MNIHFIGIGGISMSALAEICINKGYQVSGSDSNESYLLDKLRDQ
                     GATIYIGQKKDNISDDVNMVVYTAAVHPDNEELVAAKEKNKLVMNRATFLGQIMREYK
                     NSIAVSGTHGKTSTTSMLSTIFEYADLDPTILVGGNLSMIGGNVKIGNSNHFITEACE
                     YVDSFLNFNPKISIVLNVEEDHLDYFSGIDEIKASFNKFGKLLPPEGYFIINGDDENI
                     DDILYDVKATIIKYGRDSDNDAVIKDIHFDNSGHGIFRIEYEGRDLGEFELSVYGLHN
                     IYNASSAIMAALVSGIDLETIRKNIKIYKGVGRRFETKGYYKNALVVDDYAHHPTELK
                     ATLAAAKKLKKSTLWCIFQPHTYTRTKSLLGEFSEAFYAADKVIITDIYAAREKDPGD
                     IHSKDLVEKLYQNNVDAIYIKEFEDIVKYLRENVKDNDLVITAGAGPIYKVADLLVEK
                     "
     gene            36368..37246
                     /gene="purR"
                     /locus_tag="KR294_000642"
     CDS             36368..37246
                     /gene="purR"
                     /locus_tag="KR294_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HBH0238758.1"
                     /translation="MKFKRTERIGAIVKILSDNPNKIYTLSYFTNQFNAAKSTISEDL
                     LVVKNVFEKLHLGKVITISGAAGGVKYIPKTSIAENAEFLMELCERICDKSRILSGGF
                     LYLIDLIYDPTIAAKIGKIFASNIEYVDADYVVTMETKGIPMALMTAKAMNLPLVIIR
                     KDIKVSEGPTLSMTYVSGNSSKVESMSLPRKALKPDSKVIIIDDFMRGGGTIKGMVDL
                     MNEFGAEVIGTGVFISTTNPSEKMVKDYISLIQLDVNGDKIVVEPNLKTFKDEYRNED
                     LDEEEDSEFEFEIDED"
     gene            37402..37680
                     /gene="spoVG"
                     /locus_tag="KR294_000643"
     CDS             37402..37680
                     /gene="spoVG"
                     /locus_tag="KR294_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation regulator SpoVG"
                     /protein_id="HBH0238759.1"
                     /translation="MKITDVRVRKLTEEGKMKCIVSITFDNLFVVHDIKVIEGHNGLF
                     IAMPSRKVGEGNFRDIAHPINAEMRQVLEDAVLQAYHEALVQWEVAAE"
     gene            37893..39272
                     /gene="glmU"
                     /locus_tag="KR294_000644"
     CDS             37893..39272
                     /gene="glmU"
                     /locus_tag="KR294_000644"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HBH0238760.1"
                     /translation="MNFKAIILAAGKGTRMKSKYPKVIHKVCGKEMVNHIIDVSKKSG
                     VKDTVVILGHEAEVVKEKLAEEIIIAMQTEQLGTGHAVKMAKEYINDEDTIVVLCGDT
                     PLIKEETLKRLFEYHIENKYHATVLTTRVGNPTGYGRIIRDKKGDLLKIVEQKDANSE
                     EKMISEINSGIYCFNGKSLREALDLLNNNNSQGEYYLTDTAKIMRDKGLKVGAFAGST
                     IEELMGVNSRVELSKAEEIMRRRINESHMVNGVTIIDTNSTYIESDVMIGNDTIIYPG
                     VMLQGKTRIGSDCIIGMNSSITNSEIGDGTEIKNSTIIDSKVGENSTVGPYAYLRPKS
                     DLGNNVKIGDFVEVKNAIIEDGSKASHLSYIGDAHVGKNVNIGCGVVFVNYDGKNKFK
                     SIVKDNAFIGSNSNLVAPVVVEEKGYIATGSTITHDVPDGALAIARERQVIKEGWVEK
                     KNQKDDQSK"
     gene            39367..40317
                     /locus_tag="KR294_000645"
     CDS             39367..40317
                     /locus_tag="KR294_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003361732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate pyrophosphokinase"
                     /protein_id="HBH0238761.1"
                     /translation="MNTSGSEIKIIAGNSSKELAQKIADYIGVSVLDCEVGTFSDGEI
                     CVNMNETVRGCDVFVVQSTNSPVNDNLMELLILIDALKRASAGRITAVIPYYGYARQD
                     RKAKARDPITAKLVANLITAAGADRVLTMDLHAAQIQGYFDIPLDHLLGGTILANYFN
                     EKKIEDLVVVSPDLGSVTRSRKFANTLNGEVPIAIIDKRRPKANVCEVMNLIGDVKGK
                     NVILLDDMIDTAGTIVNAANALKEFGAKDVYACCTHGVLSGPAIERIANSEISELIVL
                     DTIQLPEEKRIDKIKIKTVAPLFGDAIRMIFSNESVSKLF"
     regulatory      41157..41242
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            41404..41925
                     /locus_tag="KR294_000646"
     CDS             41404..41925
                     /locus_tag="KR294_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HBH0238762.1"
                     /translation="MKLKKNKKGFTLVELLVVIAIIGILAVVAVPALFSNINKAKVAS
                     VESDYSSVKSAALSYYSDTNKIPVTTTDKTGLTILETYMESLPDKADIGGEYKLIKVG
                     SKLVLQIGTNTEGVTLTEAQSAKLLSDIGEKKIYTSATTNSLGDPLTSNTKIDNKVLY
                     IVLIDNTVMDTTK"
     gene            42077..43753
                     /locus_tag="KR294_000647"
     CDS             42077..43753
                     /locus_tag="KR294_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HBH0238763.1"
                     /translation="MAKKVRIGDKLVEKGYITEEQLKWALSEQKNSGKRLGEFLVQEG
                     LIDSNLLISVLKELLDIESIFLEGTEIDTLATKMVPENICKRYTVFPFKIDGNKICLA
                     MSDPQDREAVQDVRRMSGKDVEIFISSTEDINKAIGHAYAHSEINKAMTEYNKNRTGG
                     VRETVILEEDVNAAPIVRLVNNILENAVRMEASDIHIEQSENYMRVRFRIDGMLREYM
                     RMNSAPYKAVISRIKIMSDINISEKRIPQDGRIYLKVDNKPIDFRVSTMPTNRDEKIA
                     MRVLDKSNFMVSKEVLGIDEHGSKIYDELINTPYGLILVVGPTGSGKTTTLYSMLNQL
                     NTENRNLLTIEDPIEYELPGVNQSQINEKAGLTFASGLRAFMRQDPDIIMVGEIRDTE
                     TAEIAIRASLTGHLVLSTLHANTAVGAISRLLDMDVESFLITSSVLGVISQRLTRKIC
                     EHCKVSYEADIGEKKALGIDVNESVTIYRGKGCERCNNTGYKGRLGIFEMLEITPEIK
                     ELIDSSANQREILKMARKQGMVSLKEDIVKKVLNGKTTVEEMIRIILMTD"
     gene            43765..44973
                     /locus_tag="KR294_000648"
     CDS             43765..44973
                     /locus_tag="KR294_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HBH0238764.1"
                     /translation="MKSFKYTVIKEDGKKQTDVIEANDFNEARNLLRKRNLRVIEIKE
                     SKNKNIRLSSRKRKKDLGADQISHFCRQFAIIVSSGINSISGLETLARRSTNITLREE
                     INRIVAEIKVGSTIADSMLSSKSKFPKLLGAMVATGEATGKLDEVLKSMASFYASEHR
                     VKQKLRNAATYPLIVLISSFIMIFIFTTFMVPKMINSITTVGATLPLITRIVMGFGMF
                     MKKFWIIILLVIILFIYQFKKYLKTSVGRAHKDRVINKIPVLGKGINCMVATRFSRAL
                     YLFVSTGYPLVQGLDYIIDSVNNTMAEKILVSAKDGITRGEGLAENLERYTYFDSVLV
                     QMIAIGEQTGELENISRQMAEFYEYESEIYLNRMASMIEPVLIIAVGIIVAILVVSIF
                     MPMLSIYDAM"
     gene            44988..46700
                     /locus_tag="KR294_000649"
     CDS             44988..46700
                     /locus_tag="KR294_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PilN domain-containing protein"
                     /protein_id="HBH0238765.1"
                     /translation="MNKVYVSYYGDSISIVEGRYKHDKDKFYVKNFNVFSIEDIAQDF
                     SKEKYALLRYALENVKLKSRHVVFCLNTRDVILKPQKLPNMDKKDLDGFMKLEMDEMM
                     ALESDEYVFSYEVSSETPDNSDGDESSLNLIIGAIQKEEVNAIVEIMHEFDLVLDRID
                     TLSTAYLRMLKNLDYNDIMVTNISDNSTIINIYKKDTLFISDNIPIKITAKDMDMQLL
                     NVVEESKGLMNYYSSRNFGKVTDTILILGKRYSNKLIYETFSSAFSSYVSQGLTEIMD
                     ISDMITGDIDEDDINSIVELLGSMIEPKGKRDFENINFLPMDILRKQIKAKQMKNILK
                     IAPIVILILAIPYLCLIFSNNLANKELENVNGEIRNIESAYYQIGNIEKMIQSKSEEI
                     KVYDMLIGKKVKWENLLDDIDKNTPSKVELTSLSTTYQNLGTNNKADNSKSNKTTTDK
                     SSNNETKSSTKSDSNGDKTDNDLNEDKTTNVSEALTGNSETNSNNTDKDDKTPLYDKI
                     PNVINIEGNAKDSSYVGQFLYKLKGLYYFKDVKLHSIKSNAEDSNYTFSMTLYLKEGV
                     LTNE"
     gene            46693..47601
                     /gene="pilO"
                     /locus_tag="KR294_000650"
     CDS             46693..47601
                     /gene="pilO"
                     /locus_tag="KR294_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 4a pilus biogenesis protein PilO"
                     /protein_id="HBH0238766.1"
                     /translation="MNKDIFKKDIKDIFKMEVSLKGILIKVIILLAILSYGYFGLYPQ
                     YQKYIATKNSVKQATEKLNIYKEKTALMPKYEKQLEEVESELKEKSKNLLYDMQDGLF
                     LIGLDKKMKAYNIDLTSYDVGNVKEYEHFYGISTTISVRGDYRNVKKLMAYLEEQKNV
                     TQILDYTMTSYIEPEKEEEETTNNKDLIKNVNINKDTKIYWVEGENKWHLYKDCPLIK
                     EGEIIKNDKLLDRSTNYLCNTCVLRAATEKEAKKEVVAPKAEGVVDATFKFIMYTKEN
                     TTMILDTDNPSSWRPGKYNPFKSSAK"
     gene            47628..48194
                     /locus_tag="KR294_000651"
     CDS             47628..48194
                     /locus_tag="KR294_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HBH0238767.1"
                     /translation="MSLYKNNEKGLTLLEVIIAVFILTIVLSISYKVFNGITSAVKKQ
                     QIITDAQVNINLINKYLNRDLENCKELTKTGSGNNYEYNIEMPDNVVKYEVSIETKKN
                     TEVYSVTRIQNNTIDTENEVREEIIYNQPLVQNNKEMKETPFKIEKQTGKSIYTVSIY
                     YNESVQESHKNSNLNNKTYTFDVMSRIG"
     gene            48231..48758
                     /locus_tag="KR294_000652"
     CDS             48231..48758
                     /locus_tag="KR294_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HBH0238768.1"
                     /translation="MSKKNSERGFSLIEVLVAMAIMGIVLFAFFNIINTNNKANTKND
                     TDITSLNYVQSEIENLREKIKSGEFDFDSLDKLEDGTVVYEKLIDKSKKVVYDKVLSE
                     GDVSLYDTPYEKITTIKDEDGNLIDKGNITNKIKTIVEDKSGQIYKIAVTGKSMNDYS
                     SKKEVKIVTEIFKDK"
     gene            48779..50317
                     /locus_tag="KR294_000653"
     CDS             48779..50317
                     /locus_tag="KR294_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0238769.1"
                     /translation="MRKWNKFKSERGAALVLVLVVVALLSIVGLIFSNQIANRIKSTK
                     TTNEGIQAKYLAETCVENSIDKAYEKLYDELEKMDNEFKSENQEKSISRSKLRNISDE
                     DFNNQDEENIEAERLGYMNNINFYLNKASSDLEKASMELKKLYDLDMLDYRDIEYVDA
                     NIISHRDSILEICKNYTSGDISKINEYILKEDIDSTTLIEAKLVNNDILLKMFLEENK
                     IENEHLNSAFSHTYKALDNISLAMQNMIEYRHTFHIDEPKVEVSNGIPDSQQYYELIQ
                     NPIINNMEYSWNSKWDTLENLLEILPNQTQGFNSLRVHLRNNVRKFEKLSDNISSGKK
                     NTAKNFLKYKELLYEISDQCNQLKSMSYEKIPVKYDNMALITTFDYIQNELLAEIKCR
                     LKELKPQEIDKTEGITIKIPFYKADYDMTKEGWPKLKENGSGAELSLMVTGDKDGIKE
                     VEVTDGKKNIIGLGVEENSNSKYKVDAIVNFNLNIDTNVVGNYDIKDKILINHDISSY
                     KKVN"
     gene            50417..51499
                     /locus_tag="KR294_000654"
     CDS             50417..51499
                     /locus_tag="KR294_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilus twitching motility protein PilT"
                     /protein_id="HBH0238770.1"
                     /translation="MYIYDLLEQGIRLNASDIHITVGTNPVARVKGGFVKLSEQILTS
                     EVTMQMAKDIAGESMFKVIEEHGEADFSASLKTGERFRVNAYRQKGNYAIAIRTITAE
                     IPTFEKLGLPESIKSFTEKHKGLVLVTGPTGSGKSTTLASMINIINEKQQKHIITLED
                     PIEYVHHHKQSLVNQREVGTDTESFHSALRAILRQDPDVILIGEMRDPETVSIALTAA
                     ETGHLVFSTLHTVGAAKTIDRIVDMFQPSQQQQIKTQLSTVCEGVVSQQLLPTADGKG
                     RIAAIELMFATPAIKNLIREGKTYQIPNMIQTGVKVGMKTMDQDLMELYKNGKITKDM
                     ALSRCTDQEFMTRMIGGVNYNGYYNR"
     gene            51480..52262
                     /locus_tag="KR294_000655"
     CDS             51480..52262
                     /locus_tag="KR294_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HBH0238771.1"
                     /translation="MDIIIVNLYVFIVGIVFGSFFNVCIFRIPEGISISRPPSHCMSC
                     NTRLKPIDLIPVLSYLMSGRKCRYCYEKISSRYAIVELITGLLFLTVFMLYGISTSTI
                     YYLVLVSLLIIITFIDIDHFIIPDKILVFGAIFSMIFNLLFKEIPVKDSILGVFICGG
                     SVWIIVLLIEFVIKKECMGGGDIKLFAMLGFYMGVKNGLLTALLSVYVGAVYGICVII
                     ISRIKGKEYNSVIPYGPFISIGALITILCGKQLLELYFSMVI"
     gene            52364..53014
                     /locus_tag="KR294_000656"
     CDS             52364..53014
                     /locus_tag="KR294_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HBH0238772.1"
                     /translation="MEYIIIISLFFAHLINKSLCVFCDREKKNLYNTFFIYIITVVLS
                     VLIYLKFGISVECVQYMVLIPFLIIISIVDYYTIYVYDITIVSGIIVQGIIFLVFFNI
                     VQFDYINHIFGLLIGFIIPYIIAKLTKGLGYGDVGLYSLCCFALGNNYGFYVIVLSFI
                     LAFLFFIILYITKIFKDVDIRKQIPFTPFISLSTILIIFTEYNIFNFYYNLLYKFI"
     gene            53028..53588
                     /locus_tag="KR294_000657"
     CDS             53028..53588
                     /locus_tag="KR294_000657"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HBH0238773.1"
                     /translation="MYVVVGLGNPGKKYEKTRHNVGFDVIDILAKEYNISVTKIKHKA
                     LIGEGRVGTEKVLLVKPQTYMNLSGETLIDIYKYYKVDLSNIVVVYDDIDLEVGKIRI
                     RKKGSGGTHNGMKSITKCLGSNDFPRVRVGVSKPEAGQDLADFVLSRFRKEESDNINE
                     ALEKAADAIDSIIRENIDMSMNKYNG"
     gene            53605..56991
                     /gene="mfd"
                     /locus_tag="KR294_000658"
     CDS             53605..56991
                     /gene="mfd"
                     /locus_tag="KR294_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HBH0238774.1"
                     /translation="MNDVFLYPLQNSKEYKDIINCIKNTKGSLLVNGLLPVQKPHISY
                     SIFNDLSRQMIFITSSDLEAKKVYEDLSFYMEDKVEYLGFQDIYFYHLDAKDRNEEAK
                     KLKVLLKLANKEKIILVTSIEAVLRKYIPKQVLLDSVSHYKVGDSLDLEKLTEKLVSL
                     GYERVSKIEGFGQFSIRGGIIDVFSLEYTNPIRMELFDDEIDSIRTFDVYSQKSIDKL
                     QQFSITPSREFIYPEKTTDALVKLKKETTKNTDEGTFQNIDYISSKTYFEGAENYIDY
                     IYPEENKSIFTYLADDAIVFINDITRLKERCENYINEFRENYKLNLERGLAIKNQGKL
                     LYHYTDLEYLVKDKSVVLNSLLPKSINNFSIKSIINFESREVPTFNGKVDLLVEELNR
                     LKYNGYKIILATNTLERANKLGKDLLDKGLETTISKDRDIEIKSSQVIIVPAHINSGF
                     QYKSIKFVVITDNEMIGVYKRASKTSNKKVKKGKKIESFLDLSVGDYVVHENSGVGRY
                     TGIEQITVNAIKKDYMKIVYQGGDNLYVPIDQMDKVQKYIGAEVEKVKLNKLGTNEWT
                     KAKAKVKKEIEDMTKDLIELYAKREKIQGYKFSKDTPWQAEFESLFPYQETEDQLKAI
                     EETKKDMESSKVMDRLVCGDVGYGKTEVAIRSIFKACMDQKQVAVLVPTTILAQQHYN
                     TFKERFENYPLRVEVLSRFKTPKQQKQIIEDAKKGLVDILIGTHRIISKDINLPNLGL
                     VVIDEEQRFGVKHKEALKKIKSTVDVLTLSATPIPRTLHMSLSGIRDMSVIEEPPQER
                     HPVITYVTESKESVIQDEIERELSRGGQVFFVYNRVEHIEEMASMIQKLVPDARVAVA
                     HGRMTSKSLENIILGFLNKDYDVLVCTTIIETGMDISNANTMIIYDADKMGLAQLYQL
                     RGRVGRSSRQGYAYLLYEKDKTLSEIAEKRLKAIREFTEFGSGFKIAMRDLEIRGAGN
                     ILGSQQHGHMAVIGYDLYVKMLNDAIKKVKGEPIVEEIDVEIDLSVNAYIPDNYIKDE
                     LIKIEMYKKIASIENKEDMLDIQEELEDRFSDIPKPVQTLLTIAYIKSLCKILKIEKI
                     RQLKDEILLVPITKYRTKQKIGYNIVTELEELLEKMCKVK"
     gene            57022..58017
                     /locus_tag="KR294_000659"
     CDS             57022..58017
                     /locus_tag="KR294_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBH0238775.1"
                     /translation="MKKVITLVIAMILVVSVTACSSSKGETVATVEGTKISSDEFKKT
                     IALYKDSMEQTYGKDIWDKEVEKGVKYKDKFKDLILDQLITTEVIYSQAKKDNLLPKK
                     EDVEKSFKELKDAMGKDEKYKEQLKKLGIDDEFLRDQQEKDLAMQNYQSNFAKKTKIS
                     DEEMKKYYDTHKDEFKKDEVEASHILLKTVDDNNKPLSDKEKAEAKKKAEEALKEVKS
                     GEDFAKVAKKYSQDTSASDGGKLGFFSRGQMVAEFEDAAFSMKKGEVSDLVETQYGYH
                     IIKVTDRINEQTSFEDAKETIKDQLLKNKYQEQIEKLTKEAKVEKDEKVINKITI"
     gene            58141..58680
                     /gene="spoVT"
                     /locus_tag="KR294_000660"
     CDS             58141..58680
                     /gene="spoVT"
                     /locus_tag="KR294_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein T"
                     /protein_id="HBH0238776.1"
                     /translation="MKATGIVRRIDDLGRVVIPKEIRKTLRIREGDPLEIFTAKDGEV
                     ILKKYSPIGELNEFSQEYAETLAEVLGYGVLITDLDSIIAVSKLPKKDYKEKSISDEL
                     EAIISERTVKYSKDKNILPLFKEDQKEYTSQVIMPIISASGDCIGSIVVVSKDKDTIA
                     ESEEKSLKIAANFLGKQVQ"
     gene            58800..60413
                     /locus_tag="KR294_000661"
     CDS             58800..60413
                     /locus_tag="KR294_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBH0238777.1"
                     /translation="MNNNKNKDSFLKGALILGLAGVIVKIMGGFFRIPLGNMIGSEGM
                     GYYQAAYPVYTLFLTLATAGFPTAVAKLVSEKVAIGNFKGANKIFKVSHTVLFITGII
                     SFCILFFGADYIVTNVMKNPGALYSMKAIAPALLFVPAMSAYRGYFQGRQDMTKIAVS
                     QVAEQFFRVVLGLTLAYLLMKSLGQTFGAAGAISGATIGSIASMLYLVFAYMLGRKER
                     RAEIDASQRFKDERVSYIFKKLLTVAIPITIGASVMPLVNMIDNVIVIRRLMEAGFTY
                     KVANSMFGQLTGMAMATINLPAVITTAMSMSLVPAISKAYALGNKSKARKDTKSAVKV
                     TLLIVLPCAFGMASLAIPIMGLLFPHEPSSVGTILFTLTPCVLFLGLIQTLTGIIQGM
                     GKPIVPVIALCVGMLCKIVISYTLTGIPDINVLGSAFGTVTAYFVAAMINLLYVKKHM
                     NVNFSKKEFIIKPFITVMTMFIMVKLSYGALVGFLGNSISTIIAICVGGIVYVVVILG
                     IGGIKKEEILTMPKGDKLYKLLKKVKLIR"
     gene            60520..61968
                     /gene="mazG"
                     /locus_tag="KR294_000662"
     CDS             60520..61968
                     /gene="mazG"
                     /locus_tag="KR294_000662"
                     /EC_number="3.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphate pyrophosphohydrolase"
                     /protein_id="HBH0238778.1"
                     /translation="MGKISIVGLGPGDYSLISQGVLESLINSPKVFFRTEKHPIIDKL
                     KETIQYTSLDYFYEKEENFDNVYLKISEFIIEESAKGDLVYAVPGHPRVAEKTVSIIE
                     RLANEKHIAVEILPSMSFVDAMFNYLAIDPSEGFKLVDAFEIENSYIDLDTSMIITQV
                     YDKFIASNVKLKLMEHYDYNQEVCIVNGAGVKDLESKKFIKLCELDRNENFFDYLTSL
                     YIPKSSKKMYNTVHDLEIIVNTLRSPSGCEWDKKQTHQSLKNSVIEEAYELCNAIDNN
                     DIDEMVEELGDVLLQVIFHCQIGNEEGYFDLKEVVNGICKKLIHRHPHIFSGAKLDMS
                     KFEKTWEELKKEEKGESTITDGLRRIPKHLPALMKASKVQHKAALVGFDWDNVEDVFK
                     KIEEEYQELLDEHRVGNIKYIKEELGDLLFSIVNLARFLDIDSGEALNCTTEKFINRF
                     DFIEKSAMNLNKKLEDMTLEEMDEFWNQAKKQ"
     gene            62057..62335
                     /locus_tag="KR294_000663"
     CDS             62057..62335
                     /locus_tag="KR294_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003153447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HBH0238779.1"
                     /translation="MNKAELVSKMAEKSGLTKKEAEAALNAFMSSVQDALVNNEKVQL
                     VGFGTFETRERAARQGRNPRDPEQVIDIPASKAPVFKAGKGLKDIING"
     gene            62407..62649
                     /locus_tag="KR294_000664"
     CDS             62407..62649
                     /locus_tag="KR294_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HBH0238780.1"
                     /translation="MRLDKFLKVSRIIKRRTVAKDACDKGIVTINGKVAKSSSEVNIG
                     DTLEIQFGEKKMKFKINEVKEHVLKNDAKEMYEILE"
     gene            62711..62965
                     /locus_tag="KR294_000665"
     CDS             62711..62965
                     /locus_tag="KR294_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein YabP"
                     /protein_id="HBH0238781.1"
                     /translation="MEQNITLKDRSKLVISGVEHIYSFNDKRVELKTSVGEMVIEGEN
                     LDMSKLSIDENIISIDGTINSMVYAKPKKPQESFLKKVFR"
     gene            62966..63499
                     /locus_tag="KR294_000666"
     CDS             62966..63499
                     /locus_tag="KR294_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0238782.1"
                     /translation="MIPFTQDVSIFYATIYGGILIGVLFDFYRGLRGNFKFINYFAII
                     FDVLFWFLATVIIFVTINLTEFFDLRYYHFVALFIGFILYYNTISKIVLSIINKIIRF
                     VRNSFKKVTHYIVSFLNNLYYVIIYSLHLLFDIIFYIPNIFIATRKSIKRKSNKKLKN
                     KKKSKPKKKKNKTKKRV"
     gene            63505..63789
                     /locus_tag="KR294_000667"
     CDS             63505..63789
                     /locus_tag="KR294_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HBH0238783.1"
                     /translation="MNLRKKFSGQIIVISLFLGISIFSMMTGFVFEYTKAKEYKKEIA
                     SLNKQLKKTEIQINSLKKDEKSYEGDLEDIARKRLNMVKPNETVYVDINR"
     gene            63902..64822
                     /locus_tag="KR294_000668"
     CDS             63902..64822
                     /locus_tag="KR294_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ppx/GppA family phosphatase"
                     /protein_id="HBH0238784.1"
                     /translation="MKVGAIDIGTNSMRLLIADYRDGNFINRKKFVNTTRIGYGVDSK
                     GYIKEDAIKRNIKALKEFSDKCNDEKCEKIYCMGTSALRDSKNGDYFVKLAKEETGID
                     VDIVTGIEESNLGFKGVLEGIQGDDTIIVIDIGGGSTEFIVGDSEGIKFNKSENVGAL
                     RMTERFLKHDIIEDEEFEAMSSFIYDEIDKTLNHIKDRGLKTLIGIGGTITSLSAMNQ
                     ELEIYSMEKIHNSKIHKKEIEEILQKLIKMTLSDKKNLKGLQEKRADIITAGVKILNI
                     IMEKLEIEEITVSEYDNLEGLICQKSKKMY"
     gene            64912..67284
                     /gene="spoIIE"
                     /locus_tag="KR294_000669"
     CDS             64912..67284
                     /gene="spoIIE"
                     /locus_tag="KR294_000669"
                     /EC_number="3.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein E"
                     /protein_id="HBH0238785.1"
                     /translation="MQRSVAVVKNKTVKPNVIKLISGYIDFTTAAFAVMGFLLSRSII
                     VDSVAPLGIAFFICASKIDKYKIPVFISTLLGILLSSNDFGNVAKYAVCLTIFMAMNK
                     KLKLSDSIAKVAFIGAIILLPISMGQAFFSNRYVYGLLIAGVEAIIMFISIYVFSYGI
                     GLMANVNNRMSVRTEEAISISLLLTFSIMGIGDISLFGISIRTILSTVLILLTSIVGG
                     ATMGASSGVIIGVASILNNMTSAVYMGIYSFSGLISGAFNKINKYFCILGYILSWTII
                     YLYTSGITSNMMQLRDILLGCLIVLVLPERLFNKIEKLIKSNVASNEIVYDYIMRSKN
                     LTNSRLNSIYKTYDDLADTFDKIREKDKVLDQRDIANVIDMIHNDECKSCSMRRMCWE
                     SRFNHTYTMIYNILEKIEEKGELSLNDIPKNFRKECMKPESIVKISNHYYKMFVLDYD
                     WSVKFSESRKLIANQIRSISKSIKSLSQDLEGDIMLDIEKEKNIYEQLERYDITVDKV
                     SYLTKSNSEFEISIEKKTCHDGCMCEDKIVNIISDLVGENMSVRKIGCHCLGGKCKAT
                     FVKSQKYKAVTEVSAMSRDGHILCGDNYTYMEINDGKYMMAISDGMGKGKKAYEESSA
                     TIDILEKMIDAKIKDEIVIDTINNMLLLKSSEEMFSTLDLGILDLKRGCLETIKMGAC
                     STYIKREDGEVDLISSSSLPVGILSDVKIDRKNVKVKEGDYVIMVSDGIVDAGRNNNL
                     GDNWLIYFLKNIETTNPKEISNLILDRALELQALQIEDDMTVLVTKICTK"
     gene            67635..69527
                     /gene="pepF"
                     /locus_tag="KR294_000670"
     CDS             67635..69527
                     /gene="pepF"
                     /locus_tag="KR294_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HBH0238786.1"
                     /translation="MNRKLCKAIIPLFISIFCMLIISIKADQGYQKNNDRAITVMNNN
                     DTEDDAEKKQEIDYEKTCWNLQSLFKSDDQWKKELKSFDKDTKELKNYIGKVTKSPTH
                     LSFALNIKEKLDIRLNKLSAYVKLKQDTNKNSYKYLDMNDSMSKSYGNYMGICSDLEL
                     EILKLSNKDYKKIISNKNINRKYGAYLRDIRRNKVHYLDDKSEDILSKVSSISSLPSQ
                     VYELFRNMDRKTNLTPAQYASELESSDRENRKKAYQDELITYNDNINTIAGLITGQVK
                     KNIFYSQERGYESSLEMYLEADNVDEKVYNNLIRTVNSNMDSLHKYIDLRKKVLKLDK
                     VHSYDMFVPMVKAVDNNINYEKAQSIVYSALSPLGKEYNDVVYKAFNEKWIDVYSHEN
                     KVSGGYCLSVYENHPYILLNYNNSLGSVSTLSHELGHAVYEYLSSKNQNYFNSNPSIF
                     THEVASTTNEALLYEMLIKEAKGNDEKAYYITQYLDLIKDTLYTQTMYAEFEKTIHEL
                     VEKGKSVNALVLNDVWGQLLKKYYGQSYELDQLSKVGWARIPHFYNSFYVYKYATGCS
                     AGVSFAQDILKNGSDNYMSFLKKGSSDYPINLLKSSGINLTNTKPIENTIKKFDSLVA
                     ELEKLL"
     gene            69641..70606
                     /gene="galU"
                     /locus_tag="KR294_000671"
     CDS             69641..70606
                     /gene="galU"
                     /locus_tag="KR294_000671"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HBH0238787.1"
                     /translation="MQVKVKKAVIPAAGLGTRFLPATKAQPKEMLPIVDKPTLQYIIE
                     EAVASGIEEILIITGRNKKSIEDHFDKSVELELDLEKKGKKELLEVVQNISNMINIHY
                     IRQKEPKGLGDAIYCARHFIGDEPFAVMLGDDIVDNDVPCLKQLTDAYEEYRTTILGV
                     QKVNQEDTNKYGIIEAKNIEGRVYKVKDMVEKPESGKAPSNIAILGRYIITPEIFDIL
                     KDLPPGKGGEVQLTDALKILSKKEAMYAYNFEGKRYDVGDKLGFLEATVDFALKKEDL
                     KEDFIKYLKHVCSEFDKNNNVLYNNTDEKIDLIEVNEARELEIQK"
BASE COUNT        28568 a         7625 c        12770 g        21906 t
ORIGIN      
        1 agaggataca cctgttccca ttccgaacac agaagttaag ctctctagcg ctgatggtac
       61 ttggtgggaa actgcctggg agagtaggac gtagccacgt aatttttttt attttttgtc
      121 aaaaaaaaca aaaaatacgt atttcttttt tcatttcggg aaaactaaac acaggaatta
      181 tggactttat aaaaatttaa ttcttgagga gtgatataag tgaaaaaagt tgctttaatt
      241 ttagctataa taggtgcgct taactggggt gcaattggta ttctaggtac agacttaata
      301 ggtagtatct ttggtggaac atatgaaatg gtaagtagaa taatatactt cattgtaggt
      361 ttagctggat tatacttaat accaagttta atgtctgatg atagagaata atttatgctt
      421 ttatgttaaa tacctcattc taaatgttta gaatgaggta tttaatttta taaaaatatt
      481 aatttgtttc ttttttaatg gtaaaataga taagaattga agttttaaaa agaagtatta
      541 tgtaaaaaag gagtactatt aatatatgtt tattattaat gaattaaata agattgtaaa
      601 tgaagaagta atatcttttc atatgcctgg tcataaaaag ggacaggttt ataaaaagtt
      661 aggatataaa gatatactaa aaaatttgta taaaatggat acaactgaga tattaggaac
      721 agataattta cactttccgg aaggaattat aaaaaattca caaaaaaaag catcaagagt
      781 atttaaaagt gattatactt gctatttagt aaatggtagt agctgtggaa tacaatctgc
      841 aataatgtca gtatgtagtc ctaaaagtaa aataataaca aatagagact gtcatcagtc
      901 tgttataaat ggatgtattt taggagatat agatatagag tatgtgcctt gtgagataag
      961 tgaagagaca aatatcttaa aagggatatc tataagtaat gtgattgata taatagataa
     1021 aaacttggat gcaaaagcag tactgcttac ttatcctaca tattatggaa tgacatatga
     1081 tttagaatac atatgtaatt atgcacatag caaaaagatg gtagtgatag tagatgaagc
     1141 acatggtgcg catttagggc ttagtgagag gcttcctaaa acagctcttg agcaaggtgc
     1201 agatatagtt gtacagagta cacataaaac tcttccagca tttacacaat cgtcaatgat
     1261 acatatacag ggagaccgag ttgatataga taaaatattg aacatgttaa gaattacaga
     1321 atcttcaagc ccttcatatt tattattatc ttctctggaa ttagcagtag atatatatga
     1381 aaataaagga aaagaattaa tggaagagct tttaaataat attataactt tcaaaaataa
     1441 agttgattca aatattaata tatacgacac aaatgataaa acaaaaatat ttatatcatc
     1501 taaaaacatg ggtttaacag gttatgaact agaaaatatt ttgagaaata aatataacat
     1561 acaagtggag ttatctaatt attatggagt tcttttaata tgtacaatag gaaatactgc
     1621 tgaggatttc tctagtttag aaacagcatt aaacaatgtt gtaaaggaag actttaaatt
     1681 tgaaaagtta gaaaataaaa aataccctgt tgttattcca aagaaaatat taacacctag
     1741 agaagcattt tataaaacta aaaaaagtgt taaaatatat gacagtatag gtaaagtttg
     1801 tggtgaatgt atagttccat acccacctgg aataagtgta atatctcctg gtgaagtaat
     1861 aagtaaagaa ataatagact atctaatgtt ttgtcattct aaaggcatga ttgtgagtgg
     1921 attgaaagat gtagatttaa attttataca agtaatagat ttagaagaca tttaaaaatt
     1981 atgatataaa agtagataga agtagatagt ttaaaattgt gaagagaaat aaatagactg
     2041 cttatataga gatatctaat aaaagtacta aaaaagtaaa aagtgtttgt atggaggata
     2101 tgaaaatgaa aggtaagtta ataattatag agagtggttc agatgcaagt ggaaaggcta
     2161 ctcagacaga aatattatat gaaagattaa aaaaagaagg ctatatgatt aaaaaggtag
     2221 aatatccaaa ttatgaatct ccatcatctg ccttggtgaa aatgtaccta aaaggagact
     2281 ttggtaaaaa tgcatcagat gtagacccat atatagcatc aacttttttt acagctgata
     2341 ggtatgcatc atttaaaacc gattgggagg agttttacaa tgaaggtgga ataattatcg
     2401 cagatagata tacaacctct aatatggtac atcaggcctc taaaatggat atttgtgata
     2461 gagaagagta tttaaattgg ttagctgatt atgaatttaa tttatttaag ataccacaac
     2521 ctgattgtgt tatattttta gatgtgccta ttgaatttag taaaaagctt atggagaata
     2581 gaaaaaataa aattacaggg gaagaaaaaa aggatattca tgaaagtgac atagagtatt
     2641 tagagaaatc ttacaacaat gctttatata tagcagataa atatgattgg aaaaaaataa
     2701 attgtgtttt agataacaaa ttaagaagta ttgaaagtat acataatgaa atttataaaa
     2761 tagttcttga ttcaataaaa cctatggaga gataaatatg tattttgaaa atattatagg
     2821 gcaagatttt gcaaagaaat atttaacaaa ttctataaag aaaaataaac ttaataatgc
     2881 gtatatgttt gaaggaatgg atggaatagg aaaaaagaaa tttgcagatg aattatcaaa
     2941 actattactt gattatgaaa atctcgaaaa tagtccagac tatgtactca taaaaccaga
     3001 tggaaatagt ataaaaatag ctcaaatcag aaatttacaa tcagatatag taataagacc
     3061 tcataaagac tataaaatat atataatcaa taatgctgaa aaaatgactg tggaagctca
     3121 aaatgcactt ttaaagacgc tagaggaacc tccaaactat gctataataa tcttagttac
     3181 aaacaacaag gaatctttat tagaaactat aaaatctaga tgtgatataa taaagttctc
     3241 acctatacca attgaagact taaaacgtta tttgataaat acaggtatag aagaagaaag
     3301 agctcaatta ttggctattt tttcgagagg aagtattgag aatgctctaa atctatctca
     3361 gtcttctgag ttttcaatga tgagagaaga tatacaacag tatattcaga taatgttaga
     3421 taaaaacata gtggagattt taaatatacc aaataatatg gaaaaatata gaggtaagat
     3481 tatagcttta ttagatatga tgataaacta ttttcgagat atcatcctat taaaagaaaa
     3541 tgtaaacaag aacatgttaa taaatgtaga taagctagtt ttcattcaaa atatgaatgg
     3601 aaaaattagt tattctcaat tgtccaagat tattgatata atagaagatg caaagagtaa
     3661 aataaaaagc aattgcaatt tcaatataag catacaagtt atgtctttaa atatatacga
     3721 ggtgattaaa tgataaagat agtaggtata aggtttaaaa gtgctgggaa aatatattat
     3781 tttgaccctg ttgattttaa tatagagcaa gatatggatg tagttgtaga aactgcaaga
     3841 ggcttggagt atgggaaagt agtcgttggt ccaaaagata tggatgaaag cgaattagtt
     3901 tctcctttga agccaattat aagaatagct acagaagaag ataaaaaagt atatctagaa
     3961 aataaggaaa aggcaaaaga aacttttgag ttgtgccaac aaaaaataaa agaacatgag
     4021 ttaacaatgt ttttaataga ttgtgagtat acatttgata ggaataagtt gattttttac
     4081 tttacagcag aaggaagaat agattttaga gaattggtaa aagacttagc tgctatattt
     4141 aaaactagaa tagaacttag acaaataggt gtcagagatg aagctaaatc tataggaggt
     4201 ctagggcctt gtggtagaaa actttgttgt tcatcttggt taggtgattt tcaaccagtt
     4261 tcaataaaaa tggcaaaaga ccaaagtcta tctctaaatc caacaaaaat atctggaata
     4321 tgtgggagat tattctgttg cttaaaatat gagcatgatg tatatagtga agcaatagaa
     4381 aaaatgcctg ttgtaggtgc attggtgcaa tcagatgatg gaaaaggaaa agttgtagaa
     4441 gtgaatcctt tattagaaca aattaaagtg gaatttcaag acaagacagt aaagatatac
     4501 acaagagaag atataaaaat acttagagag cctaaaaaat gtgatggctg tggtggtaaa
     4561 tgtaaggata atgatggatt agatgaagcc acactaagag agctaaagaa attagaagat
     4621 taaatttaag gtagggcttt tcctaccttt tttaaagcaa ttaatgctta aagttattaa
     4681 tatttgagga gaatttatat atgcaattaa aagattcaga aagaatagat gatttacaat
     4741 taaaaggcct taaaattata caagatacta atggtttttg ttttggtata gatgcagttt
     4801 tattagccaa ttttactaaa ataaaaaaag atgccaaagt agtagatttg ggtactggaa
     4861 ctggcattat acctattttg atagctggaa aaagtgaagc taaaaaaatt attggcgtgg
     4921 aaatacaaga agatgtatat gaaatggcaa ctcgttctat aaaattaaat ggattagaag
     4981 aaagagttga gattataaat gaagatataa aatacataga caaagtctta gacataaatg
     5041 gttaccatgt agtcacatca aatcctccat atatgcatat tgatggaata aaaaatccaa
     5101 atgataaaaa agcaatatca agacatgaag taaggtgcaa tttggaagat gtaattagag
     5161 ctgcatccag attggttatg cctagaggaa aattcttcat gatacataga ccaacaagat
     5221 tggttgatat aataacttta gggagaaaat ataaattaga accaaaggtt attcaatttg
     5281 tgcatccaag acctcaaaaa gcaccgaact tagttttggt tcaatttgta aaagatggaa
     5341 ggccagagct taaaatattg gacccattgt atgtttatgg agaagatggg aattatacaa
     5401 aagaattaaa agcaatatat aataataaag atataggaga gttgtaaatg agcgggaaat
     5461 tgtacatatg tccaacacca ataggaaacc tagaagatat aacatataga actttaagaa
     5521 tattaaaaga agtagacttg attgcagcag aagatacaag acatagtata aaacttttaa
     5581 atcattttga aatctcaaaa ccactaacta gttatcatga acataataag gattcaaagg
     5641 gagattattt gataaataaa ctaattgatg gtgaaaatat agctctgata agtgatgcag
     5701 gtatgcctgg tatatctgac ccaggagaag agataataaa acaagctata caaaataaca
     5761 tagagataga agtattgcca ggtgcaacag cctttgtaac ggctttagtt ggctctggta
     5821 tggacacaca tagatttatt tttgagggct ttttagatag agataaaaaa gttaggaaag
     5881 cacaattgga agaattaaag gaagaaagta gaactataat tttctatgaa tcaccacata
     5941 gattgaagga tacactaaaa gatatgctta aaattcttgg taataggaat atttctataa
     6001 atagagaact tacaaaaaaa tatcaagaaa taataagaga aaatatagaa actaccataa
     6061 aaatatttga ggaaaaagaa gtaagaggag agtttgtatt aatagtagag ggttttcatg
     6121 gtgagaagtc aaagaaagaa aattatgatg ggcttacaga tagggaatat gttttaaaac
     6181 taattgaaag tggtatgaac aaaaaagatg caataaaaat agtttgtaaa gatagaaagt
     6241 taaagaaaga tgtggtttat aaacaagttt tagatttata aaacctgaat ctgaggtgat
     6301 tttatggaaa tagggaaaat tataatagag agtttaaaga gggaagatac acataaaata
     6361 tttatagaat tagataataa gcatgaatta gaaaaaataa ttcctaaaat aagctgtatg
     6421 aagtctgtag gtgaatgtaa atatcatgta gtaaattgtt ttgaacattc tataaatgca
     6481 ttaaaagaat tagaaatagt attaaatgat aaggattttt ttccaataca tctaagaaaa
     6541 catgtgtcaa actatttaaa aacatatatt gaagaaggaa taaataagtt acatgtatta
     6601 aagctgggaa catttttaca tgatataggt aagcctgaca gtatgacctt agatgaaacc
     6661 ggaagagttc atttcacaaa tcatgaaaaa ataggtgctc aaataattga caatatggga
     6721 ataaagttag agttatcaac agagacatat agacttataa gtaaatatgt aagatatcat
     6781 atgatacttt tgtctctata taagaaaaat gatttgagta ggaaagaatt aattaatgta
     6841 tttaacttag tagatgagga cactataggt gtaataatgc ttgggtatgc agatatagtg
     6901 tctacagtaa aattattggg caagagtgga gaagtcagtg tgttaaagac atatatggaa
     6961 tatattttaa caaattactt gtataagagt aattatacac atgtataaat ttagttaata
     7021 taattgagtt ttagatgatt aattgaagtt tgaaatatac ggatttcaaa aacataaaag
     7081 aagttgtctt tgttgtaaaa ttatgaaaga caactttttt tatatcaaaa attgaaattt
     7141 tattaaggat acttaatggt ctattaatta ataaaccatt agtatttaat ttatattaca
     7201 atattgattt tgcttgtatt ggcgttgata gtataacaga ggtcttagta gaaccaattt
     7261 tctttatagt atcaatcaca ttttctagct cgtacatatc ttttacaatt acttttaaaa
     7321 gtaagcaatc atcacctgtt atatggtgac attctacaat cctagggtcc tttgcagctg
     7381 actcaataaa ttctgtatat ccattgcttg gaagagaaat atgaataaat gcctttataa
     7441 ctctgcctaa tgaatctggg ttgacaatag ctttatatcc ttctataaca ccagactctt
     7501 ctaatctttt gactctttct gaaactgcag gagaagttaa accaactatt tttcctaagt
     7561 ccttcataga aattctccca tcatcctgta aaatttctat gattctgtaa tctgtaacat
     7621 ccataaataa acagtccccc ttaaataaaa ataattaatg ctataaaact tttttagaat
     7681 ctatcatttg tgtttttaaa taccaaagat ttctagataa atcaacctta taaatgtgtg
     7741 gttttgaaag tcttttgtat tgttcccaga tagtacttaa ttcatattgt acatgatttt
     7801 ttatttcaag aacagctttt ttattatatt tgcatctgcc ttttatatac aatggtttaa
     7861 gaagctcttt aactttgtaa tttgtaaata ccttcgtttt ccatgtataa gtaggatgga
     7921 agatttctaa aggtttagac tcatctataa cttcatcatg taacataatc aaatctgcct
     7981 ctgccttatt gtcttcgtta tatattctta taactttctt gtaaccagga ttatttattt
     8041 tttctggatt ctcagaaatc tttatcttag gttcaagaac tcctttttca caagatgcag
     8101 ctaatttata aactcctcca agagaaggtg aatcgaaaga tgtaatgagc tttgtaccta
     8161 ctccccatga atttatagta gctccttctg ctttaagtga tgttatggta tattcgtcta
     8221 ggtcattaga tgcagttatg ctgatatctg aaaagccagc attatctaat tgttttttag
     8281 cttctttaga taaataagct aaatctccag agtcaagtct tatacccata ggtttgtatc
     8341 ctttttcaga aatatttttg aatactttta ttgcattagg aactccactg tttaatacat
     8401 cataagtatc tacaagtagt aggcatttat ctggataaac atcagcatat gcttggaatg
     8461 cttcaagttc attatcaaat ttttgtaccc aactgtgagc ttgtgtacca attataggta
     8521 tatcaaacat tttccctgct agtacgtttg cagttccagc acaaccacca actacggcag
     8581 ccctagcccc atatatccct gcatctggac cttgtgcacg acgtaatcca aattcaaata
     8641 cagggtctcc ttgagctgca aagcaaactc tagatgcttt agtagcaata agagactgaa
     8701 aattaactat tgttaacaat gctgtttcaa taagttgagc ttgatataaa ggtgccttaa
     8761 cagtaattaa tggctcatta gggaacatga tagttccttc ctcaacagca tatatatctc
     8821 ctgtgaattt aaattctttt aaaaatttta agaacttgtc agaaaataaa tttaagtttt
     8881 ttaagtactc taaatcttca tctgaaaaat gaagattatc tatgtattca acaacctgat
     8941 caataccaca aactatagta taccctccat cacaagcgtt ttttctaaaa aacatatcaa
     9001 atacaacaat gtcttcatga atattctttt caaaatagcc atttaacata gtaagctgat
     9061 ataaatcagt aagaagtgtt agatttctca ttatttctct ccttaattat tattaaatat
     9121 taaaaattgt aaaaactccc acacttatac taaaacataa tatagtacaa ctttcaagta
     9181 taaagtatta cctaactatc ataaaattat ttaaagagga ggatgattat aataggaaaa
     9241 atatggtttt atatggtatc gataggaata ataggaagct tgatttctaa aaatatgggt
     9301 gaattaaata aagttatatt aagtgaaaca tcaaaaggta tagagtttgc aataagtcta
     9361 gctggtatca tggcactctg gatggggata atgaatatcg caaaagaatc aggtttaatt
     9421 gaaaagatag gtcaaaaact aaatcctata atgagaagat tatttccttc tattccaaaa
     9481 ggtcataaag caatgtctta tatagttatg aatattgctt taaatatgtt gggtgctgga
     9541 aatggtgcaa cagcatttgg tttaaaagca atgagtgagc ttcaaacttt gaataacaag
     9601 aaagatacag ccactaatga tatgattatg tttatggtaa tcaatatatc atctatacaa
     9661 ataattccat ttactataat caaactaagg atggatatgg gggctcaaaa tccaagtgaa
     9721 ataattttta cgactttatt tgcaaccata atatctacag cagtagcaat aataacatgt
     9781 aaattttttc aaagaagata tagataaagg ggatgtagat acatggagat attttcaaac
     9841 ttacttatac caataataat tctgtacata gtagtttatg gtaaatataa aaaaatagat
     9901 gtgtatgata gttttgtaaa aggagcaatt gatgggttaa aagcagcatg ggatatccta
     9961 ccatatataa taggtatatt tttggcaata ggaatattca aaactggtaa aggtcttgat
    10021 atgttagaat ggctatttac accaatagca aatatgatga gtataccaaa agaattaata
    10081 ggtctaataa gtgtaaaacc tttatctgga agtggtgctt tagggatgta cagtgaactt
    10141 gcaaatagag ttggaatagg aagtttagta gaaaaaatgg gtgctacgat tgtaggttct
    10201 tctgagacta ttttttacac aatggcaata tactatggaa gtctgaagat aaaaaatact
    10261 agacatacat tatcatgtgc tatgattagc catgttgcag gtgtcatagc agctgttttt
    10321 atttgctatg taatatttgt ataatttgtt gacaatatgg gaaaaatttt ataatatagt
    10381 gattatatag aaacaaatag taatacaaat tacaagctat gaaaagaaga gtaaataaag
    10441 gttttttcta tcagagagct aggttaggtg aaagctagtg tcaaaagctt tattgaagat
    10501 ggtcttggag ctttttatct gagcaagtgt gctagggtaa aacggttgga cacgttatag
    10561 tctactaagg tatctataaa atgtttctac atttcatgtg aaacataact attatagatg
    10621 aattagggtg gtaccgtgaa taatctcgcc cctatgttaa ctcataggag gcgatttttt
    10681 attatttaaa tgaaagaatc atatgattac gaacgataaa aaattaggag gtaaataaca
    10741 tgagcaaacc gagtttttat gtaacaacac caatatacta tccaagtgga ggattacaca
    10801 taggacatac ttattcaaca gtagctgcag atacaatagc tagattcaag cgtttctgtg
    10861 gatatgatgt aaagttctta acaggaacag atgagcatgg tgaaaaaatt caaaagaaag
    10921 ccatagaaca aggaatgtca gagatagagt atcttgatgg aatgataaaa gatataaagg
    10981 ccttatggaa tactatggat atatcttatg atgattttat aagaactaca gaaaaaagac
    11041 atacagacat aatacaaaag atatttacta aactatatga gcaaggtgat atatataaag
    11101 gtgaatatga aggtagatac tgtactcctt gtgagagttt ctggacagaa tctcaattac
    11161 tagaaggaaa taaatgccct gactgtggaa gagaaacata tttagtaaaa gaagaatctt
    11221 atttctttag attatctaaa tatgaagaca gattaaaaga gttatttaaa gatgatagtt
    11281 tctgttttcc tgctgctaga aaaaatgaaa tggtggcaaa ctttttagac aaaggattag
    11341 aagatttaag cgtaactaga acgacttttg actggggtat aaaagttcct tttgatgaaa
    11401 aacatgtaat ttatgtgtgg gtagatgctt tatgtaacta tataacagca ttaggttata
    11461 tgactgataa tgatgaagaa tttaaaaaat attggcctgc caatgttcaa atagtaggta
    11521 aagaaatagt gagattccat acaataatat ggccagcgct tttaatggct ttaggtctag
    11581 aagttccaaa acaagtattt ggacatggat ggatactatt tgctgatgat aaaatgagta
    11641 aatcaaaagg taatgtggtt tatccagaac ctataataga aagatatgga atagacacac
    11701 ttaagtactt cttattaaga gagtttgcat ttgggcaaga tggaagttat actcatagaa
    11761 attttgtaac gagaataaat tatgatttag caaatgattt aggaaactta ataagtagaa
    11821 ctgtagctat ggttgaaaaa tacaataatg gtataatacc aacagcaaaa gtttcaacta
    11881 attttgatgc tgacttaaaa gaacaagctg tttcaactag agaaaacttt gaagctgaaa
    11941 tggataaaat gcaattccat gaagcattag agagtgtatg gaaattagtt agaagaacta
    12001 acaaatatat agatgaaact atgccttggg cactagctaa agatgaaact aagaaagatg
    12061 aattagacac agttttatat aatttatgtg aatctataag aataatcgca acactaataa
    12121 atcctataat gaatgagact gctaataaaa tatatgaaca tataggaata aaaggtcaag
    12181 atgatataac tacatgggaa agtacaaaaa catttggtct tattggagaa aatgtaaaag
    12241 tatttaaagg tgaaccttta ttcccaagat tagatgtaga aaaagagata gaagaattaa
    12301 ctaaaatgtt ctctgggaaa cctccagtag aagaaaaacc tttagagcat aaagaagaaa
    12361 ttactattga tgatttagac aaaatagagc ttagagtagg gaaaataata agctgtgaaa
    12421 aacatccaaa agcgaataaa ttattagtat cacaagttaa gattggacca gaaacaagac
    12481 aaatagtatc aggaatagct gaatactata agccagagga tttagtagga aaagaggtta
    12541 cagtggtatg taacttaaaa ccagttaaat taagaggtgt agaatctcaa ggtatgatat
    12601 tagcagcagg tgatgatgga gacccatatg ttttaccatt tacacaaggg gctaaagatg
    12661 gatgtgaggt tcgttagtag gtaattaaat agtaaggaga ttaaagatgt tatttgactc
    12721 acatgcacat ttaaatgatg aaagttttga tgaagataga gatgaactta ttggttcatt
    12781 aaaagataaa ggtgtagatt tggttgtaaa tccaggagca gatatagaga cgtcgataac
    12841 agcaattgaa cttgcgaaaa aatacgactt tatatattca gcagttgggg tacatccaca
    12901 tgatgtatca aaactagatg atacagcaat agaaactcta agaaaacttg caactgagaa
    12961 tgaaaaagtt gtagctattg gagagattgg attagattat tattatgatt attctccaag
    13021 agaagaacaa aaagagtggt ttaagaagca aattgaatta gctaatgagc taaaacttcc
    13081 aataataata catgatagag atgcacatgg agatactttt gagataataa agaatactaa
    13141 aaatcctgaa ataggatgtg tacttcattg ttatagtggg aatgtagagt tagctagaga
    13201 atatgttaag atgggttgtt atatatcaat tccaggtacg gttactttta agaataataa
    13261 aaaaactaga gaagtagtaa gagaaatacc tctagaaaga ttattcatag agactgattc
    13321 accatatatg tcaccagagc cacatagagg aaagagaaac aatccttctc aagtatcttt
    13381 tgttgctgat aagatagccc aggaaaaagg gatatcttat gaagaagtat gtagagttac
    13441 aaaagaaaat gcaaagaaat tttttaatat aaaatagaca aattaaatct tataatgata
    13501 tatataataa gtcattataa gtataggatg agagtgcctc aaaatgagtt ttttagttta
    13561 tgaggcactc tttttgtatg aaatcaaata tattttcatc atttcaacaa tgaaaaagaa
    13621 gtttatcata ttttgagata gtttgttttt atttatttaa ttcatatttt aaaatatatt
    13681 ttcttaacat tgttaaaaaa gaatttacaa gatattcatt agaattaact caactctaat
    13741 attcacttaa cttaagttgt ttattatatt attaaagaga agtaaacgaa aagtagatta
    13801 aggaggttga attttgtata cagttgatag tactaagata ttgataaata tgaacttaga
    13861 gaaactagaa aagatatact caatgataaa agatacatca agtatttcta taattaaaga
    13921 acctaacttg gctacagtaa tggtaagagc taatgaaagt gtaaaaaaca caacatttaa
    13981 tttaggagag atattagtta ctgaatgtag tgtaaaggta gatgaaagct tgggttacgg
    14041 aatagtttca gaaaacaata ataagaaagc catttattta gcagttatag atgcagtttt
    14101 acatagcaat aacagtaaat ttgatgagtt aaagaattac ataaataaaa gtgtatatga
    14161 agagaactta aggtatgaac aagagattat tgatgaattt agcttgatta ataaaacgaa
    14221 agttcaattc aatgctatgg attaaatagg aggagaatca tggtaaatta tacacaagaa
    14281 atatatagaa agatgctaga tagtgcttca tttcctggga aattaaataa tatagataat
    14341 ataaatatag aaaataatac aaaactattg aatggagcaa ttggtatagc aatcacttta
    14401 ttagaccaag aagttacctt ctatatagaa aattatactc aaaaagatat aaaaaatata
    14461 agagcactta caatgtcaaa tcaaatagat tatagaaaat cagattatat atttttagat
    14521 attaattcag aagtggatat attacagatt aaaataggtt cttttgaata tcctgatgaa
    14581 agtgcaacta tagtacatca agtaaatgat ttatcaacgt actctcaaac taagtatata
    14641 aagcttgatt tgagtggtcc tggtataaaa tctaaaaata gtatatatat aaatggaatt
    14701 agagaagaat ttatagaaag attatctagc ataaataaag attatccaat aggaatagat
    14761 ttgattttag tagataaaaa aggagaaatt gcatttatac caaggtcatc aaaattaagt
    14821 tgggaggtat tatagaaatg gcttatgtag cagttaaagg tggagaagaa gccatattac
    14881 aggctaaaaa tatacttgag ttttataggg taaaaggaga tagcttgcct atagatgtaa
    14941 agcagattga ggaacaaatg tcttatgctg tagacaaagt aatgtctgaa ggaagtttat
    15001 acaacaagga actatcagca ttggctataa aacaagctca aggtgatata ttagaagcct
    15061 ctttctatgt aagagcttta aggtcaacaa tgcctagaat tacatattca gaacccataa
    15121 atacagaaga aatgagaata aaaagaagaa tatcagctac ttttaaagat ataccaggag
    15181 gtcagtatct tggggcaact agagactatg aaaatagaat attgaatgta gaattattag
    15241 aagaagatga aaaaaagaat agacatttta gagatagttt tataaatgaa ttagaaacag
    15301 tagatgaaat ccctgaattt acaaaaatat ctaatatatt tagaaaagaa aatttattac
    15361 aagaagaagt ttgtgaaaac aaattggaag aagttattga tgatattaca agaaatagtt
    15421 taagatttcc agtttctagg tcagcaaagt tacaggcatt aactagaggt gaaagtggag
    15481 tagtgtcagg ttttgcttat gctattgtaa gaggttttgg tgatgaacat ccatatataa
    15541 gtgaacttag aactggtaat gtatttataa aagtaaaaca tcccatctat gaagatgaag
    15601 aaataataat aggggatatg ctggttactg aatgtgaaat agtttcaaaa gcatcacaaa
    15661 ataagactga aaattctaaa actaattcgg aagataaaaa taagatgtct ttaggatatg
    15721 gtctttgtat ggggaataat gagaataagg ctatatctat ggccatacta gacaaatctt
    15781 tggagccaaa tagtgaaaaa ctagcacaag atgaagaatt tgtattgctt catatagatg
    15841 gaatagattc attaggattt atatctcact ttaagcttcc tcactatgta gattttaaag
    15901 cggatgtaga aagaataaaa tagtttgagg aggtaagttt aggtgatata taactatggt
    15961 tttttagacg aaaacacaaa aaaagaaata agaagaaaga tattaaaagc aatatcaata
    16021 cctggttatc aagttccctt tggttcaaga gagttgccta tagctaaggg atggggtact
    16081 ggaggtttac aattaacact atcattaatt ggtaaaaatg atgtagtaaa agtaattgac
    16141 caaggaagtg atgattctac aaatgcttgt aatataagga gctttattgc aagtgtaagt
    16201 aatgtagaaa ccacaaaaga tacattagaa gctacattga ttcaaacgag acatagaata
    16261 ccagaagaaa aacttaaatc taatcaaata ctaatatttc aagtaccaat accagaaacc
    16321 cttagaatag tagaacctag tgaagtagaa acaagaagaa tgcattcaga agaagattat
    16381 agtaggatgt gggtatatct ttatgaagat atagttagat ttaatgatat atctatagca
    16441 gttgaatatc catgtaaagt aaatgataga tatttaatga atccatcacc tatacctaga
    16501 tttgatataa aaaaattaaa tatgtcagac aatttattct tgtttggtgc aggtagagaa
    16561 aaaagaattt atgctattcc tccatataca aaggtagaac ctttagagtt tgaggattat
    16621 aagtttgaag aggaaaagtt tgaaggaaaa tactgtagtt tatgtaacag tacaaataca
    16681 tttttagatg aagtatatga cagtgacact aatgaaaagt actatagttg ctcagataca
    16741 agttattgtg aaaaagttag attaaaaaat aacagtatag atgtgacaat aggaggtact
    16801 tggaatgagt aaaataaatg actctaaaag attagaaaat atagacaagc aagtattaat
    16861 aggaagaaat atcaatctta tttatggaga tgggtgtgaa aagtgttttg aaagcacagg
    16921 atatgaaagc aataatatat gtaagtattg tggttctata gttgcatgta ataatgtaaa
    16981 tttagaactt tatgaaggag aagtccttgg aattgtaggt gaatctggtt caggaaaaag
    17041 cactttatta aaaatactgt ttttccaaga acatgcaaat agtggagaag tatatatatc
    17101 ccattacaat aaagacacaa atatactaga gctttcagac caaaaaaaga gatacataaa
    17161 gaatcatttt atgggtattg tgtatcaaaa tccccacctt ggtttaaatt tagactttag
    17221 tagtggtggt aatatagcag aaaaattatt gatggcaaat ttatataatg ttgaaaaaat
    17281 aagagataga ggcaaagaac ttttaataaa aactaatata cctgtagaaa gaatagacca
    17341 taaaccaaaa tactttagtg ggggaatgca acaacgagtt caaatagcaa aagctctttc
    17401 aaataaccct ccaatattgc tattagatga ggttacaaca ggtttagatg tttctgtgca
    17461 agcggaagta ttggatttaa taagagaaat ccaaagagaa cttaagattt ctatgatagt
    17521 tgtatcccat gactttgatg ttataaagat gcttgctgat aggacaattg taatgaaaaa
    17581 tggaagtgta attgagtctg gtcttacaga ccaaataatg gaggacccac aacacccata
    17641 tactcagcaa cttataaatt cattgctata aatatcgttt gtaaataagc aaaatggggg
    17701 tttttaataa aatgaaagaa actatacttg aagtaaataa ttttagtaaa gactttgagt
    17761 tacatgcatt gaacaagact ataacggcat gtagtaatat aagttttgaa gtttcaaaag
    17821 gtgagttttt aggaataata ggtaaatctg gagcaggtaa gtctaccata ttaaaaagta
    17881 tctataaaac atatatacca acaactggag aaataatttt taattcagaa atatatggta
    17941 atgtagacct ggctaaaatt ggagaccgag aaatgataaa tcttagaaag aaagaaatag
    18001 gatatgtatc acagttttta aagacacttc cacgaataac tgcaattgaa ctggtagtac
    18061 attctttaat tgagagtggg tttgaaaaag attgttcgta tgatatggca aaagatatac
    18121 ttaaccaatt tgaaataaag gaaaatttat gggatgcgta tccaaataat ttttctggtg
    18181 gagaaaaatt aagattaaat ttagctcaag ctatggttaa aaagcctaga cttttgttac
    18241 ttgatgaacc aactgcatca cttgataatc aatctaaaat atatgtaaaa gaaaaaatgt
    18301 tggagcttaa aagtcaagga actacaatga taggaatttt tcatgatata gagtttatgg
    18361 aaactgttat agataagacc tttactatga caaaagggac tataagtgaa agtggggtag
    18421 cctagatgat aaaactaatt cataatgcaa atattgtatt agaagatatg attttagaaa
    18481 atggtcattt aatcatagag ggagatacaa taaaaaaagt atcaaatgat aagattgatt
    18541 acgcatttga ctttaatgag atagatgaaa taatagatgc aaaaaactta tatgtaatac
    18601 ctggtattat agatattcac agtgatgcca ttgaaaagga aatagagccg agaccaagta
    18661 cattattacc atttaatatg gcattttatg aactagataa aaaactacct gcaaatggaa
    18721 taactacagt ttatcattct atatctttag gggatggagt aggagttaga agtattgata
    18781 actctttaaa gatgattaaa aatattgatt catataaaaa tatagatagt aagagcataa
    18841 atcataaagt tcatttaaga tatgaagtgt tgtattatga aggtttagaa aaggttttag
    18901 aactattaga tgaaaataaa atagactact tatcaataat ggaccattct ccaggacaag
    18961 gtcagtatac aaatccaaca ttttataaag agtatgctac taaagtgtgg ggagttacag
    19021 aaaattatgt agatacatgg ttagatgatt tagtaaatct gcatgataat ttagattgga
    19081 ataaaatagc taatattata ggtatagcca aaactaaaaa tataaatgtt gcatcacatg
    19141 atgatgatac attagaaaaa atggatttca taaaaaatat aggcataaat gtatctgaat
    19201 ttcctataac tcttgaagtt gcaaaacatt caaagaaatt gggtgttcta acttgtttag
    19261 gtgcaccgaa tattgtaaga ggtaaatctc ataataacaa tttaaaagca atggatgcta
    19321 tattggaaga ttgttgtgac attgtgtgtt cggattatct tccatcagct atgataaagt
    19381 ctatgtgtat agttgcagaa agaataaata atttaaataa agcagtcagt ttatttacct
    19441 caaatcctgc taaagcagtt ggtatatatg atgaaagagg tagtataaaa gaaaataaaa
    19501 aagcagattt agttttagta gatattgata gtgaatatcc aaaggttgta aatactattg
    19561 taaatggaaa aacagtttat aaaagggagg tataaagatt gctaacagag ttacattgtc
    19621 atacaagtat atcagataat aattttacta ctgaagaaat aataaaaaaa gcagcagaaa
    19681 agaatataaa tatcttagca ataacaaatc atgacacatt atctggattg gatgaagctc
    19741 ttgtgcttgg agagcattat ggaataacaa taataccagg tatagaaatt tcagcctatg
    19801 attataaaaa tagaaaaaga gttcatattc ttggatataa catagattta aacagtcaag
    19861 aaataaaaaa tttgtgcaat ccaatggtat gtgacagaca taaagcatct gttaagatgg
    19921 taaataaaat tatagattta ggatacaaaa tatctctgga agatgtaaag aaatattcat
    19981 caaagactgg aatatttaaa caacatataa tgaaagctct tatagataaa ggatatacag
    20041 ataatatata ttcaaatcta tataaagaat tgtttcatag aggaaacggc aaggtatatg
    20101 tatctttaaa atatgtggat tacagagatg caataaaagc tataaaaaat tctggtggaa
    20161 tttgtgtgtt agctcacccg ggtcaaatgg ataattttag cgctattgaa gagatggtaa
    20221 aagtaggatt agatggaata gaagtatatc atccatctca caacaaagaa ctagaaaaag
    20281 agtcgctttc ttatgctaag aagtataatc tagtggtcac aggaggttca gattaccacg
    20341 gattttattc tcaacataat tatgaacttg gaagcaagag cttaaataaa gaagatttat
    20401 ttaagtttag gttagcttta ggaggggtat tataaatgtc ttttttacaa gtaaaaaatg
    20461 taggtaaaag ttatggacaa gttaaggtgt taaaagacat atctattgat attgaaaaag
    20521 gagagtttat ttgtttacta ggtccaagtg gttgtggaaa gagtacacta cttagaataa
    20581 ttgcagggct tgaggataaa catggtggaa aaataataat aaatgataag gatatgacta
    20641 attcaccacc tgaaagtaga aattttggta tagtttttca atcatatgca ttatttccaa
    20701 atatgaatgt ttacaaaaac atagcctttg gactagaaaa taaaaacata agtaaatcta
    20761 atattgataa aaaagttaaa gaagttctag aagttgtaga attaagtgga tatgagaaaa
    20821 aatatccatc acaattatca ggtggacaac aacaaagggt tgcattagct cgtgcgattg
    20881 ctttagagcc agacttttta cttcttgatg aacctttatc tgcattagat gcaaaagtaa
    20941 gacttaaact tagggagcag attagaagtt tacatagaaa actaggcatt acaactataa
    21001 tggtaacgca tgaccaagaa gaagctcttt gtttagctga taagatggtt gttatgaata
    21061 gaggagaaat aatacaagtt ggaacgccaa aggaggtata taaaaatcca gaaacacctt
    21121 ttgtagctga ttttatagga acaataaatt ttatagatga tggtattaat aagatagcta
    21181 ttagaccaga agatataaaa gtagagtcta atagagattc taaagataag gatataaaag
    21241 tgggagaaat tttagatatc gaatttagag gatttaacta tagaattaca gttgagtatc
    21301 gttctaagca aatgaaatta gatgtagttt ccaaagttgc agaacaaatg aaactgtgca
    21361 taggttctaa aataaacttt aagataccta aagaaggaat tgtacaatat aaatcagagg
    21421 gatgtgctta atagctaggg gtgaataaat gataacatca aaaaataaaa gaagaataag
    21481 tgatagcaca atacaaaaat atttcttgat tttttcggta attgtactaa tagtatttat
    21541 attatttcca ttagtatcat tattaaaaaa tgcatttatg gatacaagtg gaaattttat
    21601 aggaatttca aactttagta aatatgttga aaatccaagt cttatagcat catttaaaaa
    21661 ttcaattttt gtatctacag tctcatcttt aatatcacta tgtttagcat ttatatattc
    21721 atacgcaata acaagaacaa acataaagtt taaagatttt tttaaaacta tgggaatgtt
    21781 tccacttttt gcaccaacta tgttatatgg tatttcactt atataccttt ttggaaataa
    21841 gggaatcttt acaaccatgg gtctggaagt accactatat ggtccattag gaataattat
    21901 ttctcagatt ctatttacat ttccacaagc ttttttaata ttatctgtag cactttcgat
    21961 ggctgattat agactttatg aagcagcaga tagcttgggt gctagtgaat ttaagaaatt
    22021 ttgcaaaata acaattcctg gtataaagta ctcattactt agttcattct ttgtatcctt
    22081 tatacttgca tttacagatt ttggagcagc taaggtagtc ggaggaaact acaatgtact
    22141 ggctactgac atatataaac aagtagttgg acaatttaac ataccaatgg gagctactgt
    22201 ttctatggta atgttaattc ctgtactaat agcatttaca ttagataaga tggcaagtaa
    22261 gaaacaaggt atgaccataa ctgcaaagtc tatgccatat aagattaagg aaaataagtt
    22321 tagagataga gtatttttaa tagtatgtag ttttataaca ttgctaattt ttattttaat
    22381 attcgtttca gttataggtt cagttataaa gttatggcca tataatttaa gctttacaat
    22441 ggaacactat acatttaaag gtattttggg aagtggaata aaaacatact taagcagttt
    22501 gaaaatatca actttaacag caatatttgg aactatattt gtatttttta gtgcttatat
    22561 gatagaaaag gtggataagt ttcctaaatt aagacaaaca gcttaccttt tatcaatgat
    22621 accaatggcc ttacctggct tagttttagg tatatcatat ataacttttt ttaactcagc
    22681 aagtaatcca ttaaattttt tatatggaag tacagcaata ttagttatag taaatgtagt
    22741 tcatttttat tcagtttgtt ttataacctc aaattcatct ttaaaaatgt tggataaaga
    22801 gtatgaatta gttgcaaaat ccataaatat tccattctat aaagtatttt ttaatataac
    22861 agttccaatg tctataacat caatacttga aatagtagta tattattttg taaattcaat
    22921 ggttactgtt tcagcattaa tatttttata tacacctcaa actcagactg catcaatatc
    22981 aatactaaag ttagatgaga taggatatat aggaacatca gctgctatgg cagtattagt
    23041 gcttttaaca aatataatag taagactttt gtacgaattt gtaacaaaga aattaaaaaa
    23101 taacacacaa aaatggcagc aaaaagatgt tgcatagggg aggtaaaaat gaaatttaag
    23161 aagctagttt ctttaggagt attatcaaca cttttattaa gtgtaataac aggatgtagt
    23221 actgattcat caggttcaga ttcaaagtct gatagtaaga caaaagggga tttaacagtt
    23281 tacacagcaa ttgaagaaga tagtatagag ccatatttag ctacatttaa agagaaatat
    23341 ccagatatta aattaaatat tgttagggca tcaacaggag atataacagc aagattatta
    23401 gcagaaaagg ataatcctca agcagatgtt gtatggggag ttgcagccac aagcttattg
    23461 gttgcagatg accaggggat gttagaacca tatgctccaa aaggttctga agaaatagag
    23521 tctgcattta aagatgataa agaagttcct tcttgggttg ggatagatgc ttggatgaca
    23581 ggtataacag taaacactaa agaattaagt gataagaaca tcccagttcc tagttcttac
    23641 gaagatttaa taaagccaga atataaaggt cttatatcta tgcctaatcc atcttcttct
    23701 ggtacagggt acttaacagt atcagccctt atacaaatta tgggtgaaga aaaagcatgg
    23761 cagtatatgg ataaattgca tgagaatatt ggtgtataca ctcaatctgg ttcagctcca
    23821 gctacatcag cagcttcagg agaatatcct attggtatat cttttggata tagaggtata
    23881 aagttaaaag aggaaggcta tccagtagaa gtagtatttc caaaagaagg ttctggatgg
    23941 gatatagaag caaatgctct tgtgaaaaaa gataatataa aagaagcatc aaaagtattt
    24001 ttagattggg ctataagtaa agatgtaatg aacgaatact ctaagaacta tgcagttact
    24061 actatttcta caggaaatcc aataccagaa ggattcccta aaaagccatt agagcaaatg
    24121 atagataatg atttaaaatc agcagcaaaa aatagagaag atatactaaa taaatggata
    24181 tcaaaatatg atggtaagac agaaaaagag agttaagtaa aactatacaa atggagtaaa
    24241 aagaaagaat ttttttaagt agattttatt ataataatat aagttgagaa taatataggt
    24301 caagaaaagt gaatattcta taaaaatgta tagagtaagt ataccattca gtttgaatgg
    24361 tatatttttt atttttagag attaatttag aaatagatat actacagttt aaaatagtat
    24421 attttaattt cattattaaa gtatagatat tatatataaa gtaaataaat tattgagcga
    24481 ttattaataa gatatgtata aattttaatt tgggaacttg tgttatatat catgaaaaaa
    24541 gagaaaaaat aaaaggtaaa ttgtttcttg ataacttgaa attggaagtg agaatattta
    24601 actagagaag aattatttaa gtttaagtca gctttaggag gaggaattat aaatgtcttt
    24661 tttacaagta aaaaatgtag gtaaaagtta tggacaagtt aaggtgctaa aagacatatc
    24721 tattgatatt gaaaaagggg agtttatttg cttattaggt ccaagtggtt gtggtaaaag
    24781 tacattgctt agaataattg caggacttga ggataaacat gatggaaaaa taataataaa
    24841 tgataaggat atgactaact caccacctga aagtagaaac tttggtattg ttttccaatc
    24901 atatgcacta tttccaaata tgaatgtata taaaaatata gcctttggat tagaaaataa
    24961 aaatataagt aaatctgata tagataagaa ggttagagat attttagaag ttgtagaatt
    25021 aagtggatat gataaaaaat atccatcaca attatcaggt ggacaacaac aaagggttgc
    25081 actagctcgt gcgattgctt tagagccaga ctttttgctt cttgatgaac ctttatctgc
    25141 attagatgca aaagtaagac ttaaacttag ggaacagatt aaaagtttac atagaaaact
    25201 aggcatcaca actataatgg taacacatga ccaagaggaa gctctttgtt tagctgataa
    25261 aatggttgtt atgaataatg gagaggtaat acagattgga actcctaaag aagtctataa
    25321 aagtccaaaa acaccttttg tagctgattt tataggaaca ataaatttta tagatgatga
    25381 tgtgaatatg atagcaatta gaccagaaga tataaaggta gaatttaata gagactttaa
    25441 agaaattgat gtaaaagtag gagagatttt ggatatagaa tttagaggat tcaactatag
    25501 aattacagtt gaatattgtt ctaagcaaat aaagttggac gtagtttcaa aggtagtgga
    25561 acaaatgaaa ctatgtgtag gttctaaaat aaacttcaag atacctaaag aaagaaccat
    25621 acaatataaa tcagagggat gtgcttaata gctagaggtg gataaatgat aacaataaaa
    25681 aataaaagaa gaataagtga tagtaagata caaaaatgtt ttttagtttt tttagtgatt
    25741 gcattagtag tatttatatt atttccatta atatcactat taaaaaatgc atttatggat
    25801 acaagtggaa gttttgtagg aatttcaaac tttagtaaat atattgaaaa tcccactctt
    25861 atagcatcat ttaaaaactc aatttttgta tctacaattt catccttaat atcattatgt
    25921 ttagcgttta tatattcata tgcaataaca agaacgaata taaggtttaa aaactttttt
    25981 aaaactatgg gcatatttcc gcttttcgca ccagctatgc tatatggtat ttcacttata
    26041 tacctttttg gaaacaaggg aatctttaca attataggca tagaagtacc actatatggt
    26101 ccattaggaa taattatttg tcaaatactg tttacatttc cacaggcctt tttaatatta
    26161 tctgtagcac tttcgatggc tgattataga ctttatgaag cagcagatag cttaggggct
    26221 agtgaattta agaagttctt caaaataaca attcctggta taaagtattc attagttagt
    26281 tcgttctttg tatcttttat acttgcattt acagattttg gagcagcaaa gatagttgga
    26341 ggaaactaca atgtattggc tactgacata tataaacaag tggtaggtca atttaacata
    26401 ccaatgggag ctactgtctc tatggtaatg ttaattcctg tactaatagc atttacagta
    26461 gataagatag caagtaaaaa gcaagggatg actataactg caaagtctat gccatataag
    26521 attaaggaaa ataagtttag agatagagta tttttaatag catgtagttt tataacttta
    26581 ttaatcttta ttttgatatt tgtttcagtt ataggctcag ttataaaatt atggccatat
    26641 gatttaagct ttacaatgga acactatacg tttaaaggta tatcaggaaa tggaatcaaa
    26701 acatatttaa gcagtttaaa aatatcaatt ttaacagcaa tatttggaac tatatttgta
    26761 ttttttagtg cttatatgat agaaaaagtg gataagtttc ctagactgag acaaatatct
    26821 tattttttat caatgatacc aatggcatta cctggtttgg ctttaggtat atcgtatata
    26881 acttttttca attcagcaag taatccatta aattttttat atggaagtac aacaataatg
    26941 gttatagcca atatagttca tttttattca gtttgcttta taacttcaaa ttcatcttta
    27001 aaaatgttgg atagagagta tgaattagtt gcaaaatcta taaatattcc attttataag
    27061 gtgttttttt atgtaacact tccaatgtcc ataacatcaa tacttgaagt ggctgtatat
    27121 tacttcgtaa attcaatggt tactgtttca gcattaatat ttttatatat acctcaaact
    27181 caaactgcat caatatcgat actaaagtta gaagagatag ggtatatagg gccatcagct
    27241 gctatggcag tattagtgtt tttaacaaat ataatagtaa aacttttgta tgaattgaca
    27301 acaaagaaat taaaaactaa gacacaaaaa tggcaacaaa aagaagttgc atagaggagg
    27361 taaaaatgaa atttaggaaa ttagtctctt taggaatatt atcaacactt ttattgagtg
    27421 taataactgg atgtaataat gcttcatcag gttcaaattt aaagtctaat aataagataa
    27481 aaggagagtt aacagtttat acagcaattg aagaagatag tatagataca tatttaacta
    27541 catttaaaga gaaatatcca gatattaaat tgaatgtact tagattatca gtaggagata
    27601 taacagcaag attattagca gaaaaagata atcctaaagc agatgtgtta tggggggttg
    27661 cagctacaag tttgataatt ttagatgaca aagaaatgct agagccatac gctccgaaag
    27721 gctttgataa ggtaaatcct gtatttaaag atgataagaa agttccttct tgggttggaa
    27781 tagatgcttg gatgactggt ataacagtaa atactaaaga attaagtgat aagaacatac
    27841 cagttcctag ttcttatgaa gatttaataa agccagaata taaaggtctt atatctatgc
    27901 ctaatccagc ttcttctgga acaggatatt taacagtatc agaacttata caaattatgg
    27961 gtgaagaaaa agcatggcag tacatggata aattacataa aaatattggt gtatacactc
    28021 agtctggttc agcgccagct atattagcag cttcaggaga atatcccatt ggtatatctt
    28081 ttggaaatag aggtataaag ttaaaaggtg aaggttatcc agtagaagta gtatttccaa
    28141 aagaaggttc tggatgggag atagaatcaa atgcacttgt gaaaaaagat aatataaaag
    28201 aagcagcaaa agtattttta gattgggcta taagtaaaga tgcaatgaat gagtattcta
    28261 agaattttgc agttactaca attgacacgg gaaatccggt gccagaagga tttccaaaga
    28321 atccattaga acagatgata gataatgatt taaaatcagc agcaagaaat agagaggcta
    28381 tactaaataa atggatagaa aaatatgatg gaaagacaga aaaagagagc taagccttac
    28441 aataaaattt agtacaaaaa gcgcctagaa tataagtttt atatctaggc tcttttgata
    28501 tatttattta aaatgcatat ttctatataa aaataaatag tttagtacct tgattaaatt
    28561 aaataaaaac cttaaaataa agagatgtaa agaaaaacta aaaacgaata aaaggtgaat
    28621 ttatatgata aaagaaataa tagtagtaga gggtagagat gacgttacag cagttaagag
    28681 agcaatagat gcagaactta taactacagg tggatttgga tttccaaaag gtgtaatgga
    28741 gcgtataaaa gctgctaatg aaagacgtgg tgttataata tttacagacc cagattttgc
    28801 aggtgaaaaa ataagaaaaa aaatagcatc agaagttcca ggatgtaaac atgcatttct
    28861 accgagagag gaagctaaaa aggatggaga tataggtatt gagaatgcta ctcctcaaag
    28921 tataatagca gctctgaata aagttagaac tgaaaataca gaaaaaagat atgaatttaa
    28981 gcaagttgac ttaattagaa atggtcttat aggtaatgaa gaagcatcac ttagaagaga
    29041 tgcacttgga aaaatacttg gaattggata tggaaatgca aaacaatttt taaatagatt
    29101 gaataattat ggagttgaaa gagaagaatt tatagatgca ttaaaacaaa tctaaacgta
    29161 atgtttaatg tatgaaaaat atgtatataa aataaattgt ggaattacgg ttaatttaag
    29221 ataaattatt tataatatat accttatttt aaatcaatgt aaatacatat aaataagtat
    29281 aattaataaa attaaatatc aaaataagtt aaaaaggagt aaataatgga tagactatct
    29341 tcacataatg caacaaagga agtagtacaa aaatataatt ttaaattttc aaagtcttta
    29401 ggtcaaaatt tcttgataga tagtaatata attgataaaa tcttatctgg agctagaatc
    29461 acaagaggag ataatatcat agaagtagga cctggtatag gaactcttac tcgtgagatg
    29521 ggtaaaatag cagaaaaagt agtggctata gaaatcgata gaaatttaat tcctatattg
    29581 aaagatacct tgtcagattt agataataca gaggttgtaa atcaagatat actaaaagta
    29641 gacatacagg aattagtaaa agataaatta aatggtgggc cagttaagct tgtagcaaat
    29701 cttccatatt atataactac tccaatagtt atgaaatttt tagaggaaga catacctgta
    29761 acagatatag tagtcatggt tcaaaaagaa gttgcagata gaatgaatgc tattccgggt
    29821 actaaagatt atggggcatt atctatagct gttcaatact attgtgatac agagattgtg
    29881 gcaaaagctc caagacatat gtttatacca caaccaaatg tagattccac agttataggt
    29941 ctacatgtaa gagataaaag aaaatatgat gttcataatg aagacatatt ttttaaaaca
    30001 gtaaaagcat cctttggaca aagaagaaaa actcttctta attcgttggg aggtcttggt
    30061 tttcttaata aagatgaaat aagagaaata ttaaaagaag ctaatataga cgaaaaaaga
    30121 aggggtgaaa ctcttagtat agaagagttt tcagttcttt caaatataat aaatacaaaa
    30181 gtatcttcta aatagaaggt acttttttta attttgttaa catatattgt ttagagaaac
    30241 tgtgttaagg ggggattgca gtgggttcta aaagaaagtt taaaagagac tatataatac
    30301 tagaagctaa agacataaac tttagataca aagaacgagt actgccaaaa gcttttgcaa
    30361 aagttgaagt aaatgatgaa aaagcaatta ttgcattata tgtagaaaat ctaaaatatg
    30421 ttaaagatgg gtataaagca gtagcaataa aagatgacca tggattaata gacttaggaa
    30481 atataatttt aaatgaacaa ggaagaggtg aatttgtttt agatttagaa gattatgatg
    30541 atgagataaa aggtattgca ttattgtatg aaagaaatat acctttaatt ggatttaaag
    30601 gaaataagct tgaaaattat gaggacatat tatttcaaga ggtagaggaa gaagaatatg
    30661 aagaatatga agagttggaa gaagaagacg aagagataga ggataatgag gaaagtgata
    30721 gagacgaagg tagtgaagaa gaatatatta tagaagaata tgatgaagat gagtatgaag
    30781 actattggga agatgatgaa gatattgaag aaggagagtt aaaagcaaga acggaagtag
    30841 aagattctag tgatgaggaa atagaagagt tcaataatta taaggaaata gaaaattata
    30901 atagggttaa agtacaggaa gaatatatag acatagaata tgatgaggaa gaagaggaag
    30961 aagaagaagt ttttgaagta aatagagaag aagataggtt tgtttcctca aaacctacta
    31021 aatcaaagaa agttcaaaaa gatcagaata atattgaaaa aataaaaaga gctaatggag
    31081 taagtcaagg agagagtgga aataaacaaa ccagtacatt acttatgcca agacaaataa
    31141 aaaaaggttt gaaattattt aaagaagtaa aaccttttgt aacagattat atagataaga
    31201 caagatggtg gaaaatagag ataaatccta caacactgtg tggatataca atgccttatt
    31261 taggatattt aaatgtattg aattacacta tgtatagtga tgcagtttta cattcatata
    31321 aatacagaca ctatttattt ggtgttcagt atgatgaata taataagaga aaacattata
    31381 tttatgctat cccaggaaat agaaatgaac agccagacaa tggaagcaca ggatttttaa
    31441 gatatcaagc ttgtgataat agaacaaata gtttaggata ttggctatgt tttatagatt
    31501 ctagacaaag aaatatagtt aggtaaaaat aataaaaatg aaaaaattta gactcaattc
    31561 ttattttact gaaaaaatta atgaaatgta gtacaaaact ttaaaaacta ttgataatat
    31621 ttaaatatta cactacaata tatcttgaaa tacctattat attatggagg aaaattatga
    31681 taaacgagca aagaatttta aatgagtttc ttgaattagt acagatagat agtttatctt
    31741 taaaagaggg gaatgttgct aaagtattag ttaaaaaatt agaagaaata ggttgttcag
    31801 tagtaataga caatgctggt gaaaaagcaa atggagaaac tggtaatata atagctacat
    31861 taaaaggaaa taaagaagga aagaaaatat tatttagttc acatatggat acagtaactc
    31921 caggtatagg ggtaaaacct atagtggatg aagcaaatgg aataataaaa agtgatggta
    31981 ctacaatatt aggttctgat gataaagcag gtatagcagc tatattagaa ggcttaagat
    32041 atataaatga aaataacata gaacatactg atatacaagt tgtattctct atatgtgagg
    32101 aatgtggatt agttggagct aaaaatttag actatggaaa aatagattct gaatatgcat
    32161 ttatattaga tagtggtggt tctccaggtg aaataatagt aaaagctcct gcacaagatg
    32221 taataaatgt taagatatta ggaaagactg ctcatgcagg tcttgaacct gaagctggaa
    32281 taagtgctat aatggtagct gccagagcaa tagaaaatat gaatttactt agaatagacg
    32341 aagaaacaac tgctaacata ggaattataa acggtggaac agctacaaat atagtaacag
    32401 gagaagttaa tataattgca gaagccagaa gtctaaaaga aaataaatta gatgttcaaa
    32461 ctaaacacat ggtagagact tttgaaaaag ctgcaaaaga ttttggagct caaattgaga
    32521 tagatgtcaa tagagcatat acaccaatag atgttagtga ggattctgaa ataataaaac
    32581 ttgcaaagaa ggctttttca aacttaggta tagaaggtca tactgaatct acaggaggag
    32641 gtagtgatac aaatatatta agtaagaatg gtatcgaagc tataacttta ggaattggga
    32701 tgaaaaatgc tcatacacta agtgaacata tagctataaa agacttatat gattctgcta
    32761 aaatggtagt ggagataata aaggaagcat aaatttaaat aatagtgtat aatatatata
    32821 tcgcctagct taagctaggt gatttttcat tttatagaag attgataatc tctattgaaa
    32881 gcaaagagta tacatttgca tataagagag tgtttaattt atgttcaaat gtaggttctt
    32941 aataatattt agattgtttc ataagggagg aataaatatg gaaacaaggt atgaagaagc
    33001 aaataaaata acaatacaat caatactttg gaatgtagta ttaacaataa ttaaggttat
    33061 agctggtgtt attggtaatt ctagcgctat gattgcggat ggattacatt cagcatcaga
    33121 tattataagt tctataggag tactaatagg caattatgta tcttctagac ctggagatag
    33181 agagcataat tatggtcatg agaaagcaga gacattagta tcatttgtgt tatcaatatt
    33241 gcttattttc gtttctataa caataggtat agaggcaatt aaatctttat ttaacttaga
    33301 tgcattaagt gttccatcaa tattaccatt agtagtatca gttatttcaa tcctgataaa
    33361 agagtatcaa tatagaataa caataaaagt tgctaaaaag ataaattcac cagccctaaa
    33421 agctgatgct tggcatcata ggtcagatgc tttatcttca gtagctgctt ttataggtat
    33481 aggtggttct attttagggt ttaaaccatt agacccaatt gcgtcagttg tagtggctat
    33541 atttgtagct aaagtaggaa ttagtatact tataagttct gttaatgaat tgatggatgt
    33601 ttcagttgat gaagaagaga taaaagaatt aaaatttatt gtagcagata cagaaggtgt
    33661 taaaaatctt ggtgatataa agactagaaa acatggagct atggcatatg tagatttgac
    33721 tatatgtgtg gatgaaaatt tgacagttaa gcaaggtcat gatattgcta ccaagcttga
    33781 aaaacatata ataaaacata tggaatttgt aaaaggcata acagttcacg ttgaaccatg
    33841 tactaattgc caaggaaata agtgtaataa ttaattaaaa cttaaaaaaa agtgtaaaaa
    33901 gttatataat tgttttatga ttataaactc taggggtggt taaatgagca agaaaagaaa
    33961 actaaagaaa aaagctgcaa tattaatagg agtagttgtt ttctttataa tatactttat
    34021 atcctttaga ataggaataa atatggaaaa ggataaaagt gaagtgccaa agaaggtaga
    34081 aaaagaagaa gaagataata ggtctttaag gactcaaata aaagagaaga agaaggttta
    34141 tatatcagat aaaaatatag aaaacataaa aattgaagaa gatatgtggg atgaaataaa
    34201 gttatttttc tcagatttta agaaagtaag aaatactact tcttcttacg aagcagttta
    34261 tgaaggttat tctgatgatg gagttaaatt ttctactgac cttaactttt ttagagtata
    34321 tactgtaaat aaagaagaat attataaagt accagttagt tctaaggatg cttttaagaa
    34381 acttttagat gagagcatat atacttcgtt tgacctttta agtcattata aagattggaa
    34441 agaggttact ataactcatg gaaaagaaat taaaaaagtt catagatgga aatttgatga
    34501 tttagcacat aagatgattt caaagagggt tgtaggaaaa gttcaacctg agaaaagtaa
    34561 ggaaagaagt gactataatt ttactataaa tataaaaggt gataattttg atgtaaaagt
    34621 tgatacaatg ggaaaagatt atgtaaaagt tacttctaag aaaaatgtat cttactatga
    34681 ggttcataca agtttatttg attaccttaa aaatgagata tttgaaattg gaaagaaata
    34741 agactttaag aaggctatca aattagatat ttgatagcct aaattatttt tatatattat
    34801 ttttcaacca acaagtctgc aaccttataa attggaccag caccagcagt tattactaaa
    34861 tcattatcct taacattttc acgtaagtat tttactatat cttcaaattc ttttatatag
    34921 atggcatcta cattgttttg atataatttc tcaaccaagt ccttagaatg tatatctcca
    34981 gggtcttttt ccctagcagc atatatatct gttatgataa ctttatcagc agcatagaat
    35041 gcctctgaaa attcacctaa aagagatttt gttctagtat aagtatgtgg ctggaagata
    35101 caccataaag ttgatttttt taattttttg gcagcagcta aagttgcttt taactcagtt
    35161 ggatgatgtg cataatcatc tactactaaa gcattcttat aatacccttt agtttcaaat
    35221 cttcttccga cacctttata aatttttata ttttttctta tagtctctaa gtcaatacca
    35281 gaaacaagag ctgccattat agcagaagaa gcattgtata tgttatgaag accatataca
    35341 gaaagttcaa attctcctaa atctcttccc tcatattcta ttctaaatat tccatgacca
    35401 ctattgtcaa agtgaatatc ttttattaca gcatcattgt cagaatctct accgtatttt
    35461 ataatagtag ctttaacatc atacaatatg tcatcaatat tttcatcatc gccatttatt
    35521 atgaaatagc cttctggggg taataatttt ccaaatttgt taaaagaagc cttgatttca
    35581 tctattccag agaaataatc aagatggtct tcttcaacat ttaaaactat agatatcttt
    35641 gggttaaaat taaggaaact atctacatat tcacatgctt cagttataaa gtggttggaa
    35701 ttacctatct taacattacc acctatcata cttaagttac caccaactag tatagttggg
    35761 tctaagtctg catattcaaa gattgtagat aacatagatg ttgtagaagt ttttccatgt
    35821 gttccagaaa ctgctataga atttttatat tccctcatga tttggcctaa aaaagttgct
    35881 ctgttcatta ccaatttatt tttttcttta gcagccacaa gttcttcatt atctggatga
    35941 actgctgctg tataaacaac catatttaca tcatctgata tattatcttt tttctgacca
    36001 atataaatag ttgccccttg gtccctaagt ttgtctaata ggtatgattc gtttgaatcc
    36061 gaacctgaaa cttgataacc tttattgata catatttcag ctaatgcact catgctgata
    36121 ccgccaattc ctataaagtg tatattcata ataaaaccac ctttcttttt aattaagtcc
    36181 tacaatatga actatttctg tggtataata atataatgtt caatatttta taattaatat
    36241 gcatataata ttatatgtat tttatttttg aatataataa aacataagta atattatacc
    36301 acaataagaa ttgttatgca ttagttagtt taacgttata taaaggtact tgtaggagga
    36361 aataataatg aaatttaaaa gaacagagag aattggagca atagttaaaa tactgtctga
    36421 taatccaaat aaaatatata ctttaagtta ttttacaaat caatttaatg cagcaaaatc
    36481 aacaataagt gaagatttat tagttgtaaa aaatgtattt gagaagctac atttaggtaa
    36541 agttataact atttcaggag cagcaggagg agtaaaatat atacctaaaa cttctatagc
    36601 agaaaatgca gagttcttaa tggaattatg cgagagaata tgtgacaagt ctagaatact
    36661 atctggtggt tttttatact tgattgacct aatttacgac cctacaatag ctgctaagat
    36721 aggaaagata ttcgcatcaa atattgagta tgtagatgca gattatgttg tgacaatgga
    36781 aacaaaaggt atacctatgg cacttatgac tgcaaaagct atgaatttac ctctagttat
    36841 aataagaaaa gatataaagg tatcagaagg tcctacactt agcatgacat atgtgagtgg
    36901 aaacagttct aaagttgaaa gtatgagttt gccaagaaaa gctcttaaac cagatagtaa
    36961 agttataatt atagatgatt tcatgagggg tggaggtact ataaaaggaa tggtagacct
    37021 tatgaatgaa tttggtgcag aggttatagg tactggagta ttcatatcta caacgaatcc
    37081 ttcagaaaaa atggtaaaag attatatttc tttgattcaa ttggatgtta atggagataa
    37141 aatagtagta gaaccaaact taaagacttt taaagatgaa tatagaaatg aagatttaga
    37201 cgaagaagaa gattcagaat ttgaatttga gatagatgaa gattaataaa aaaaatattt
    37261 agaaaaatat gtaaaaataa aaagaggata tccctagttg ttcatagaat tatttaaaaa
    37321 acagtttata ttaatttatt ccagcgataa taattttaat ataaattaat ttctgtcaaa
    37381 atcaaagggg gatattttgg tatgaagata actgacgtaa gagtaagaaa attaacagaa
    37441 gaaggtaaga tgaaatgtat agtttcaata actttcgata atttgtttgt agtgcatgat
    37501 ataaaagtta tagaaggcca taatgggcta tttatagcaa tgcctagcag aaaagtaggc
    37561 gaaggaaatt tcagagatat agctcatcca ataaatgcag aaatgagaca agttttagaa
    37621 gatgcagttt tacaagcgta tcatgaagca ttagttcaat gggaagtagc tgctgaataa
    37681 taataaatat ataaaatgga gagagcccga acatttaggc tctttttaaa tgtagaattt
    37741 ctattaaaat atgtactttt tagtaaaaaa gtgctatatt attagtgata atgtatatgt
    37801 tgtatacaaa ttgttagata aatgtattat aatgtatatt gattaagaga ataatacgaa
    37861 taaaattaaa ttagattgaa tggagtgtat caatgaactt taaagctata atccttgctg
    37921 ctggcaaagg aacaagaatg aagtctaaat acccaaaagt tatacataaa gtatgtggaa
    37981 aagaaatggt taaccatatt atagatgttt caaaaaaatc aggggtaaaa gatactgtcg
    38041 tgattttagg acatgaagct gaggtagtta aagaaaagct tgcagaagaa attataatag
    38101 ccatgcaaac agaacaactt gggacaggac atgctgtaaa gatggctaaa gaatatatta
    38161 atgatgaaga tacaatagtt gtactttgtg gagatactcc acttataaaa gaagagacac
    38221 taaagagact atttgaatat catatagaaa ataaatatca tgctacagtt cttacaacaa
    38281 gagttggaaa tccaacaggt tatggtagaa taataagaga taagaagggt gaccttctta
    38341 aaatagtgga acaaaaagat gcaaattcag aagaaaagat gataagtgag ataaactctg
    38401 gaatttattg ttttaatgga aagagtctta gagaagcact agatttgcta aataataaca
    38461 attcacaagg tgaatattat ttaactgata ctgctaaaat aatgagagat aaaggattaa
    38521 aagttggtgc atttgcaggt tcaactattg aagaacttat gggcgttaac tcaagagtag
    38581 aattatcaaa ggcagaagaa attatgagac gaagaataaa tgaatctcat atggtaaatg
    38641 gagtaactat aatagacact aactctacct atatagaatc tgatgttatg ataggcaatg
    38701 atactataat atatccaggt gttatgttac aaggaaaaac aaggataggt tcagattgta
    38761 taattggaat gaattcatct ataacaaatt cagaaatagg tgatggtaca gaaataaaaa
    38821 attcaactat aattgatagt aaggttggag aaaattctac tgttgggcca tatgcatatt
    38881 taagaccaaa gagtgactta ggaaataatg taaaaatagg cgattttgta gaagtaaaaa
    38941 atgctattat agaagatggc tcaaaagcat ctcacctttc ttatatagga gatgcacatg
    39001 tcggtaaaaa tgtaaatatt ggatgtggag tagtatttgt aaactatgat ggtaaaaata
    39061 aatttaaatc aatagtaaaa gacaatgcgt ttataggttc aaattctaat ttagttgcac
    39121 cagtagttgt agaagaaaaa ggatatatag caacaggttc aacaataaca catgatgtcc
    39181 cagatggtgc tttggcaata gcaagagaaa gacaagttat caaagaagga tgggtagaaa
    39241 aaaagaatca aaaagacgac caaagtaagt aattatgtag tttattattt tggctaaaaa
    39301 atttagctcg aaattattat aaattatatt cattagtatt ttaaaatttt caggagggtt
    39361 acataaatga atactagcgg aagcgagatt aaaattattg caggtaattc atcgaaagag
    39421 ttagcacaaa aaatagctga ctatataggt gtatcagtac tagattgtga agtaggtaca
    39481 tttagtgatg gtgaaatatg tgtaaacatg aatgagacag taagaggttg tgatgtgttt
    39541 gtagtgcaat ctactaacag cccagtaaat gataacttaa tggagttatt aatcttaatt
    39601 gatgcgttaa agagagcatc agcaggtaga ataacagcag ttattcctta ctatggatat
    39661 gcaagacaag acagaaaggc taaggcaaga gatccaatca ctgctaaatt agttgcaaat
    39721 ttaataactg ctgctggagc agacagagta ttaacaatgg atttacatgc agctcaaata
    39781 caaggatatt ttgatatacc attagaccac ttactaggtg gaacaatatt agcaaattat
    39841 tttaatgaaa agaaaataga agatttagta gtagtatctc ctgacttagg aagtgttact
    39901 agatcaagaa aatttgctaa tactttaaat ggagaagttc caatagctat aatagataaa
    39961 agaagaccga aagctaatgt atgtgaagtt atgaacttaa taggtgatgt taaaggtaaa
    40021 aatgttatac tattagacga tatgatagat acagcaggaa caatagttaa tgctgcaaat
    40081 gcacttaaag agtttggagc aaaagatgtt tatgcttgtt gtactcatgg tgtgttatca
    40141 ggtccagcta ttgaaagaat tgctaattca gaaataagtg agttaatagt tcttgatact
    40201 atacaacttc ctgaagagaa aagaatagat aagataaaga taaaaacagt agctccttta
    40261 tttggagatg ctataagaat gatattctct aatgaatcag taagtaaatt attctaattt
    40321 attgtattta tgagagttgt ttaaaaggat ataaaccttt tgagcaactc ttttttgatt
    40381 ttatacttat ggaatgttat ttttttcttg ttagaaagat atatattatt gtaaaaagag
    40441 attatagttt aaaattatgt atatttaagt aaaataaacc taataaagga tacattattc
    40501 aaaatattat gaatataaaa aatattacaa aaaagtattg aaaaaattca gattatgtag
    40561 tattatgtaa atataaataa agaaagaggt gtttccaatg ggaaggttag aagatgaacc
    40621 cctaataatt aaatgattca gtcacaatct aaagtgaata taaaaatcta ttgaaagttt
    40681 atttataaga attgaaaata gtatctattc tatctttagt gtttgtgaga gggttctgga
    40741 ttatataaga ttactgtaaa gagtaatttt gcacaataag catatctgta aatgaagagt
    40801 ttcgtttata taatgattgt ggctgaatca taactataat agatagaatg tttataatag
    40861 atgattttat aaaatactat attgtaatag cttttagctt tcaaataaat attagcaaag
    40921 gatggaaatg acaatgataa aactaaatga taatttataa atatctcctt acgatatata
    40981 ataattgtag ggagatgttt ctttttttgt atagtataat tttttctaga aattctgttt
    41041 caatatgtaa aaagttggta tatataaata gtataaactg tgttgctaaa atatggtaga
    41101 tattatataa tataagtgga tatgtatata cattatgagt tatataattt tgaatttaat
    41161 aaaatagaaa cgttgattta tgttctgtaa tgtgggcacc ttggagcata ttgagttagt
    41221 ggtgcaaccg gctatgaaat tgtatttatt tatagatact attattttca tagctttttt
    41281 tatttaaaaa atggttatat gttagaaata aatttggtta gtacgtttaa ataattttac
    41341 ttagattttt aaccagatat attataagta agtattaatt aaaaaattta agggggaata
    41401 aaaatgaagt taaaaaagaa taaaaaaggt ttcactttag tggaattatt ggtagtaatt
    41461 gcaattatag gtatattagc agtagtggca gttccagctt tatttagtaa tataaacaag
    41521 gctaaggtag caagtgttga gtctgattat agttcagtta agagtgcagc attatcttat
    41581 tattcagata ctaataagat accagttaca acaactgata aaactggttt aactatttta
    41641 gagacttata tggagtctct gcctgataaa gctgatatag gtggagaata taaattgatt
    41701 aaagttggta gtaaattggt attacagata ggtacaaata ctgaaggagt taccttaaca
    41761 gaagcacaat cagcaaaatt attgagtgat ataggtgaaa aaaaaatata tacaagcgct
    41821 acaacaaata gtttgggaga tccattaaca agtaatacaa aaatagataa taaagttcta
    41881 tatatagtac ttatagataa tactgtgatg gacacaacaa aatagttaaa acaatatttt
    41941 tataaagaat attgtaaatt taatgaaaaa tataatataa aagacaggaa gaaaatcttc
    42001 ctgttttttt atactatttt ctttaatgtt caattatgaa tgatgatata attgagatag
    42061 taaaggagtg aaacctgtgg ctaaaaaagt tagaatagga gacaaactgg tcgaaaaagg
    42121 atatataaca gaagaacagc ttaaatgggc actatcagaa caaaaaaaca gtggaaaaag
    42181 actaggagaa tttctagtac aagaagggct tatagatagt aacttactaa taagtgtatt
    42241 aaaagaactc ttggatatag aaagtatatt tttagaaggg acagaaatag acactttagc
    42301 tacaaagatg gttccagaaa atatatgcaa aagatatact gtatttccat tcaaaataga
    42361 tggaaataaa atatgtctag ccatgtcaga cccacaagac agagaagcag ttcaagatgt
    42421 aaggcgtatg tcaggtaaag acgtagagat atttatatca agtacagaag atataaacaa
    42481 agcaataggt catgcttatg cacattcaga aataaataag gcaatgactg agtacaacaa
    42541 aaatagaact ggtggagtaa gagaaacagt aatacttgaa gaagatgtaa atgctgctcc
    42601 aatagtacga ttagtaaata acatactaga aaatgctgtt agaatggaag caagtgatat
    42661 acatatagaa caaagtgaaa attacatgcg tgttaggttt aggatagatg gaatgttaag
    42721 agaatatatg aggatgaact cagcaccata taaggcagta atcagccgta tcaagataat
    42781 gtcagatata aatatatctg aaaagagaat accacaggat ggtagaatct atttaaaagt
    42841 ggataataaa cccatagatt ttagggtttc tacaatgcca actaacaggg atgaaaagat
    42901 agctatgagg gttcttgata agagtaattt tatggttagc aaagaagtac taggaataga
    42961 cgaacatggc tctaagatat atgatgaatt gataaacact ccttatggtc ttatattggt
    43021 tgttggccct actggaagtg ggaaaaccac tacattgtat tcaatgttaa atcaactaaa
    43081 tacagaaaat agaaatctat taacaataga agaccctata gagtatgaat tacctggtgt
    43141 aaatcaatct caaataaatg aaaaggcagg gcttactttc gccagcggac ttagagcttt
    43201 tatgcgtcaa gacccagata taataatggt tggagagata agagatactg agacagcaga
    43261 aatagcaatt agagcttctc ttacaggaca tttagtttta agtacattac atgcaaatac
    43321 agcagttgga gcaatttcac gtcttttaga tatggatgtg gaaagttttt taataacttc
    43381 atctgtttta ggtgtaatat ctcaaagact tacacgaaaa atatgtgagc attgtaaggt
    43441 ttcatatgaa gcagatattg gagaaaaaaa ggctcttggt attgatgtaa atgaatcagt
    43501 aactatttat agaggaaaag gttgtgaaag gtgtaataat actggatata aaggacgtct
    43561 aggtatattt gaaatgcttg aaattactcc agaaataaaa gagttaatag attcatctgc
    43621 aaatcaaaga gaaattttaa agatggctag aaaacaaggt atggttagct taaaagagga
    43681 tatagttaaa aaagttttaa atggaaagac aacagtagaa gaaatgatta gaataatttt
    43741 gatgactgat taaaggatga tattatgaaa agttttaaat acacagtaat aaaagaggac
    43801 ggaaaaaagc aaactgatgt gattgaagcc aacgatttta atgaagctag aaatcttctt
    43861 agaaagagaa atcttagagt tattgaaatc aaagaaagca aaaataaaaa tataagatta
    43921 tctagtagaa agagaaaaaa agacttagga gctgaccaga taagccactt ttgtagacag
    43981 tttgctatta tagtatcttc tggtataaat agtatttctg gattagaaac attagctaga
    44041 aggtcaacta acattacatt aagagaagaa attaatcgta tagtggcaga aataaaagta
    44101 ggttctacta ttgcagattc aatgctttca tcaaaatcaa agtttccaaa gttacttggt
    44161 gctatggtag ctacaggtga agctacaggt aaattagatg aagtattaaa aagtatggct
    44221 tcattttatg caagtgaaca cagggttaaa caaaagctta gaaatgctgc aacatatcca
    44281 ttaatagttt tgatttcttc atttataatg atttttatat ttacaacatt tatggtgcct
    44341 aagatgatta attcaattac aacagtagga gcaactcttc cacttataac aagaattgtt
    44401 atggggtttg gtatgtttat gaagaagttt tggataataa tacttttagt tattatatta
    44461 tttatctatc agtttaaaaa atatctaaaa acgtcagttg gaagggctca taaagataga
    44521 gttataaata agatacctgt tttaggaaaa ggaataaatt gtatggtagc tacacgattt
    44581 tcaagagcat tgtatctatt tgtatcaaca ggatacccat tagttcaagg gcttgattat
    44641 attatagata gtgtaaataa caccatggca gagaagattt tagtatcagc taaagatgga
    44701 ataacaagag gagaaggctt agcagaaaat ttagagagat atacgtattt tgactctgtg
    44761 ttggtacaga tgatagctat aggggagcag acaggggaat tagagaatat aagtagacag
    44821 atggcagaat tttatgagta tgaatccgag atttatttaa ataggatggc ctcaatgata
    44881 gagcctgttt taataattgc agttggtatt atagttgcga tactggttgt atcaatattt
    44941 atgccaatgc ttagtatata tgatgccatg taggagggaa aggacaaatg aacaaggttt
    45001 atgtatcata ttatggcgat tctatttcca tagttgaggg cagatataaa cacgataagg
    45061 ataagtttta tgtaaaaaat tttaatgtgt tttcaataga ggatattgca caagattttt
    45121 ctaaggaaaa gtatgctcta ttgagatacg cattagaaaa tgttaagtta aaatcaagac
    45181 atgtagtttt ttgtttaaat acaagagatg taattttaaa accccaaaaa cttcctaata
    45241 tggacaaaaa ggatttagat ggatttatga agctagagat ggacgaaatg atggctttgg
    45301 agtcagatga atatgtattt tcgtatgaag tatctagtga aacacctgat aattcagatg
    45361 gcgatgaatc aagcttaaat cttatcattg gagctataca aaaggaagag gtaaatgcaa
    45421 ttgtagagat aatgcatgaa tttgatttag tattagatag aatagataca ttatcaacag
    45481 cttacttaag aatgcttaaa aatttagact acaatgatat aatggtaacc aatataagtg
    45541 acaatagcac aattataaat atatataaga aagatacttt atttattagt gataatatac
    45601 ctataaagat aactgctaaa gatatggaca tgcaattatt aaatgtagta gaagaatcaa
    45661 aaggtcttat gaattactat tcgtcaagaa actttggtaa ggttacggat actatattaa
    45721 tattaggaaa aagatattcc aataaattaa tttatgaaac ttttagctct gcattttcaa
    45781 gctatgtttc tcaaggcctt actgagataa tggatatatc tgatatgata actggagata
    45841 tagatgaaga tgatataaat tcaattgtag agcttttagg aagtatgata gaacctaaag
    45901 ggaaaagaga ttttgaaaat ataaactttt taccaatgga tatacttaga aaacagataa
    45961 aagctaaaca aatgaaaaac atactgaaaa ttgctccaat agttattttg attcttgcta
    46021 taccttattt atgtttaatt ttttcaaata atttagcaaa taaggaactt gaaaatgtta
    46081 atggtgaaat aagaaatatt gaatctgcat attatcagat tggaaatata gaaaaaatga
    46141 tacagagtaa aagcgaagaa ataaaggtat atgatatgtt aattgggaaa aaggtaaagt
    46201 gggaaaattt attggatgat atagataaaa atactccaag taaagttgaa ctaacaagtt
    46261 tatcaacaac ttatcaaaat cttggaacta ataataaagc tgataattca aaaagcaata
    46321 agactacaac agataaatca agtaacaatg aaacaaaatc aagtacgaaa agtgatagta
    46381 atggagataa aacagataat gatttaaatg aagataagac tacaaatgtg tcagaagcat
    46441 taactggaaa tagtgagact aatagtaata acacagataa agatgataaa actccattgt
    46501 atgataagat accaaatgtt ataaatatag aaggaaatgc taaagattcc tcttatgtag
    46561 gtcaattttt atataaatta aagggattat actatttcaa ggatgttaaa ttacatagca
    46621 taaaaagtaa tgcagaagat tctaactata catttagtat gacattatac ctgaaagaag
    46681 gtgtattaac taatgaataa agatatattt aaaaaagata taaaagatat atttaaaatg
    46741 gaagttagtc taaaagggat tcttataaag gttataattt tattagctat tttatcatat
    46801 ggttattttg gactttaccc tcaatatcag aaatatattg ctacaaaaaa ttctgtaaaa
    46861 caggctactg aaaaattaaa tatatataaa gaaaaaactg cacttatgcc aaaatatgaa
    46921 aaacaacttg aagaagttga aagtgaatta aaagaaaaaa gcaaaaatct tttatatgat
    46981 atgcaagatg gtcttttttt aataggttta gataaaaaaa tgaaggctta taatattgac
    47041 ttaaccagtt atgacgttgg aaatgttaaa gaatacgaac atttttatgg tatatcaaca
    47101 acaataagtg ttagaggtga ttatagaaat gtcaaaaaat taatggctta tttagaagaa
    47161 caaaaaaatg ttactcaaat actagattat acaatgactt catatataga accagaaaaa
    47221 gaagaggaag aaacaacaaa caataaggat ttaattaaaa atgtgaacat aaataaagat
    47281 acaaaaatat actgggtgga aggcgaaaat aagtggcatt tatataagga ttgtccattg
    47341 ataaaagagg gagagattat aaaaaatgac aaacttttag ataggtctac taattatcta
    47401 tgtaatactt gtgtacttag agctgcaaca gaaaaagaag caaaaaaaga agtcgtagct
    47461 ccaaaggcag aaggtgtagt agatgctaca tttaaattta taatgtacac taaagagaat
    47521 actacaatga tacttgatac agataatcca tcttcatgga ggccaggaaa atataatcca
    47581 tttaagtcta gtgcgaaata aagctaagta agctttaaag ataggtgatg agtttgtaca
    47641 aaaataatga aaaaggtctt actttattag aagtaataat agctgttttt atactgacaa
    47701 tagttttaag tatttcttat aaagtgttca atggtataac atcagcagta aaaaagcaac
    47761 agattattac agatgctcaa gtaaatatta atctaattaa taagtatcta aatagagatt
    47821 tggaaaactg taaagaacta actaaaactg gttcaggtaa taattatgaa tacaatatag
    47881 agatgccaga taatgttgta aaatatgaag tttctataga aactaaaaaa aatacagagg
    47941 tatattctgt aacgagaatc caaaacaata caattgatac agaaaatgaa gttagagaag
    48001 aaataatcta taatcaacca ctagttcaaa acaataaaga aatgaaggaa acaccattta
    48061 aaatagaaaa gcaaactggt aaatctattt atactgtaag tatatactat aatgaatcag
    48121 tgcaagaaag tcataaaaat agcaatttaa ataacaaaac ttatacattt gatgttatgt
    48181 caagaatagg gtaataagaa tttattaaaa aataagtagg ttgataaaat atgagtaaaa
    48241 agaatagtga aagaggattt tccttaattg aagtgttagt agctatggct attatgggaa
    48301 ttgtactatt tgcatttttt aatattatca atactaataa caaagcaaac actaaaaatg
    48361 acacagatat aacttcctta aactatgtcc aaagtgaaat agaaaatcta agagaaaaga
    48421 taaaaagtgg agaatttgat tttgatagtt tagataaact agaagatgga actgtcgtat
    48481 atgaaaaatt aatagataaa tcaaaaaaag ttgtatatga taaagttctt agtgaaggtg
    48541 atgtgagctt atatgatact ccatatgaaa agattacaac aataaaagat gaagatggta
    48601 atttaatcga caaaggaaat attacaaata agataaagac tattgtagaa gataaaagtg
    48661 gtcagatata taaaatagct gtaactggga aaagcatgaa tgactattca agtaaaaaag
    48721 aggttaaaat tgtaactgaa atatttaaag ataaataatt ttacttgggg gtgagatttt
    48781 gaggaagtgg aataaattta aaagtgaaag aggggcagct ttagttttag ttttggttgt
    48841 agtagcattg ctttctattg ttggattgat attttcaaat cagatagcca atagaataaa
    48901 atctacaaag actactaatg aaggtataca agcaaagtat ttagcagaga catgtgtgga
    48961 aaatagtatt gataaagcat atgaaaaatt gtatgatgag cttgagaaaa tggataatga
    49021 gtttaaaagt gaaaatcaag aaaaatccat atctaggtca aaattaagaa atatatcaga
    49081 tgaagatttt aataatcaag atgaggaaaa tattgaagca gaaagacttg gatatatgaa
    49141 taatataaat ttctatttaa ataaagcttc ttcagacttg gaaaaagcta gtatggaatt
    49201 gaaaaagcta tatgatttag atatgttgga ctatagagac attgaatatg tagatgcaaa
    49261 tattatttca catagagatt ctatcttaga aatttgcaag aattatactt ctggagatat
    49321 tagtaaaata aatgaatata ttctgaaaga agatatagac tcaactacat tgattgaggc
    49381 aaagttagtg aataatgata ttcttttaaa aatgttttta gaagaaaata aaattgaaaa
    49441 tgaacattta aattcagcct tttcacatac ttataaggca ttagataaca tttctttggc
    49501 gatgcaaaat atgattgagt atagacatac gtttcatata gatgagccaa aagtagaagt
    49561 atctaatggg attccagact ctcaacaata ttatgaacta atacaaaatc ctataataaa
    49621 taatatggag tatagctgga atagtaaatg ggatacatta gaaaacctat tggaaatttt
    49681 accaaatcaa actcaaggat ttaattcttt aagagttcat ttgagaaata atgtaagaaa
    49741 atttgagaag ttaagcgata atatatctag tggtaaaaaa aatacagcaa aaaatttctt
    49801 aaagtataaa gagttattgt atgaaatatc agaccaatgt aatcaactaa aaagtatgtc
    49861 ttatgagaaa atacctgtta aatatgataa catggctttg ataacaactt ttgactatat
    49921 acaaaatgag cttttagcag agataaaatg cagattaaaa gaattaaaac cacaagaaat
    49981 tgataaaaca gaaggtatta ctataaaaat acctttttat aaggctgact acgacatgac
    50041 aaaagaagga tggcctaaat taaaagaaaa tggttcaggg gcggagttaa gcttaatggt
    50101 aactggtgat aaagatggaa taaaagaagt agaagttaca gatggtaaaa aaaatattat
    50161 tggtttaggt gttgaagaaa attcaaattc aaagtataag gttgatgcca ttgtaaactt
    50221 taatctaaat atagatacaa atgtagttgg aaattatgat ataaaagata aaattttgat
    50281 taatcatgat ataagttcat acaaaaaagt aaactaaata taagaagcaa cttagtataa
    50341 ataaataata aaataatttt attatttact actaaaaaaa taagtaaact aatagaagat
    50401 atggagagta aatattatgt atatttatga tttattagag caaggtataa gactaaacgc
    50461 atcagatata cacataacag ttggaacaaa tcctgtagct agagtaaaag gtggatttgt
    50521 aaaactaagt gaacaaatat tgacatcaga agtaacaatg caaatggcaa aagacatagc
    50581 aggggaatct atgtttaaag taatagaaga acatggagaa gctgattttt cagcttctct
    50641 aaaaacagga gaaagattta gggtaaatgc atataggcaa aaaggaaatt acgcaatagc
    50701 aataaggact ataacagcag aaattccaac atttgaaaaa ttaggccttc cagagagtat
    50761 aaaatctttt actgaaaagc ataaaggatt agttttagtt acaggtccaa caggaagtgg
    50821 taaaagtaca acacttgcaa gtatgataaa tataataaat gaaaaacaac aaaaacatat
    50881 aattacactt gaagacccga tagaatatgt acatcatcat aaacaaagtt tagtaaatca
    50941 aagagaagta ggaactgata cagaaagttt tcattcagcc cttagagcta ttttacgtca
    51001 ggacccagat gtaatactaa taggagagat gagagaccct gaaactgttt caatagcatt
    51061 aacagcagca gaaacaggtc atttagtatt ttcaacacta catacagtag gggcagctaa
    51121 gacaattgat agaatagtag acatgtttca accatcccaa cagcaacaaa taaaaacaca
    51181 gttatctaca gtttgtgaag gtgtggtatc acagcagtta cttcctacag cagatgggaa
    51241 aggcagaata gcagcaattg aattgatgtt tgctactcca gcaataaaaa acctgataag
    51301 agaaggcaaa acatatcaaa ttccaaacat gatacaaact ggagttaaag taggtatgaa
    51361 aactatggac caagatttaa tggaacttta taaaaatgga aagattacaa aagatatggc
    51421 acttagtagg tgtactgacc aagagtttat gacaagaatg ataggtggag taaactacaa
    51481 tggatattat aatcgttaat ctatatgtat ttatagtggg tatagtgttt ggaagtttct
    51541 ttaacgtctg tatttttagg attccagaag gtatatctat ttctagacca ccttctcatt
    51601 gtatgagttg taatactaga ctaaagccaa tagacttaat accagtgcta agctatttaa
    51661 tgagtggtag aaagtgtaga tattgttatg agaaaatttc tagtagatat gctatagtgg
    51721 aattaattac aggactttta tttttaacag tatttatgtt atatggaata tctacatcaa
    51781 ctatttatta tttggttctt gtgtctttac tgattataat tacatttata gatattgacc
    51841 actttataat accagataaa atattggttt ttggagctat attttctatg atttttaacc
    51901 ttttatttaa agaaattcca gttaaggatt caattctagg tgtttttatt tgtggaggaa
    51961 gtgtctggat tatagttctt ttgattgaat ttgtaataaa aaaagagtgt atgggtggag
    52021 gagatatcaa actatttgca atgctaggtt tttacatggg tgttaaaaat ggtcttttga
    52081 cagccttact aagcgtttat gtaggagcag tctatggaat ctgtgtaata attataagta
    52141 gaataaaagg aaaggaatat aattctgtta taccatatgg accttttata tctattggag
    52201 cattaataac aatcttatgt ggaaagcaat tacttgaact ttatttttct atggttatat
    52261 agatgatagt caagttaaat aaagttttaa tttaaaaaaa tgaattaaag tatttaataa
    52321 ggacaatatt attattaacc ctattactaa agtgctacaa actatggagt atataataat
    52381 aatttcctta ttttttgcac atttgataaa taaatctcta tgtgtttttt gtgatagaga
    52441 aaagaaaaat ttatataata cgttttttat ttacataata actgtagttt tatctgtatt
    52501 aatatatcta aaatttggga ttagtgtaga atgtgtacaa tatatggttt taattccatt
    52561 tttaataatt atatccattg tagattacta cacaatatat gtatatgata taacaatagt
    52621 tagtggtata atagttcaag gtataatttt tttggtcttt ttcaatatag ttcaatttga
    52681 ttatataaat catatatttg gactattgat aggctttatt ataccttata ttattgctaa
    52741 actaacaaaa ggattaggct atggagatgt aggtctctat agcttatgtt gctttgcatt
    52801 gggaaataat tatgggtttt atgtgatagt tttatcattt attttagcgt ttttgttttt
    52861 tattatttta tacataacta aaatatttaa agatgtagat ataagaaagc aaattccttt
    52921 tacacctttt atttccttgt caacaatttt aataatattt acagagtata atatatttaa
    52981 tttttattat aatttgttat acaaatttat ataacaggag gtaagaaatg tacgtagtag
    53041 tagggttagg taatccagga aagaagtatg agaagactag acataacgtt ggatttgatg
    53101 ttatagatat tcttgctaaa gaatacaata ttagtgttac taaaataaag cataaagctt
    53161 tgattggtga agggagagta ggtactgaaa aagtattatt agttaaacca caaacttata
    53221 tgaatttaag tggagaaaca ttaatagata tatataaata ttataaggtt gatttaagta
    53281 atatagtagt agtatatgat gatatagatt tagaagttgg aaagatacgt ataagaaaaa
    53341 aaggaagtgg aggaactcat aatggcatga aatctataac taagtgccta ggttcaaatg
    53401 actttccaag agtgagagta ggtgtatcta aaccagaagc tggtcaagac ttagcagact
    53461 ttgtactttc tagatttaga aaagaagaat ctgataacat aaatgaagca ttagaaaaag
    53521 cggcagatgc tattgactca ataataagag aaaatataga tatgtctatg aacaaatata
    53581 atggatagtg agagggagat ttaaatgaat gatgtttttt tatatccttt gcaaaattca
    53641 aaagagtata aagatataat aaactgtata aaaaatacaa aaggctcatt attggttaat
    53701 ggacttttac cagtacaaaa acctcatata tcgtattcta tatttaatga tttatcacga
    53761 caaatgattt ttataacgag tagtgattta gaagcaaaga aagtatacga agatttaagt
    53821 ttttatatgg aagataaagt tgaatattta ggttttcaag atatttattt ttatcacttg
    53881 gatgcaaagg acagaaacga agaagcaaag aaattaaaag tattgttaaa actagcaaat
    53941 aaagaaaaaa tcattttagt aacttctatt gaggcagttt taagaaaata cataccaaaa
    54001 caagttttgc tcgatagtgt atctcattat aaggtgggag atagcttaga cttagaaaag
    54061 ttaactgaga aattagtttc attgggatat gaaagagttt caaaaataga ggggtttggt
    54121 caatttagta taagaggtgg aattattgat gtattttcac ttgaatatac aaatccaatt
    54181 cgtatggaat tatttgatga tgagatagat tccatacgaa cttttgacgt atattcacaa
    54241 aaatcaattg ataaattgca acaattctct ataactccat ctagggaatt tatttatccc
    54301 gaaaaaacta cagatgcatt agttaaatta aaaaaagaaa caactaaaaa tactgatgaa
    54361 ggtacatttc aaaatataga ttatatatca agtaagactt attttgaagg tgcagagaac
    54421 tatatagatt atatttatcc agaagaaaac aaaagtatat ttacttattt agcagatgat
    54481 gcaatagtat ttatcaatga tataacgaga cttaaagaaa gatgcgaaaa ttatataaat
    54541 gagtttagag aaaattataa attaaatctt gaaagaggtc tggctattaa aaaccaaggt
    54601 aaattgttat atcactatac agatttagag tacttagtaa aagacaagtc tgtggtatta
    54661 aactcgctat tgccaaagtc tataaataac ttttctataa aatctataat aaattttgaa
    54721 agtagagaag ttcctacatt taatggaaag gtagatttgc ttgtagaaga attaaatcgg
    54781 ctgaaatata atggatacaa aataatttta gcaacaaata ccttagaaag agcaaataaa
    54841 ttaggaaaag atttattgga caaaggctta gaaacgacca tttctaaaga tagagatatt
    54901 gaaattaaat cttcacaagt tataattgta cctgcacaca taaacagtgg ttttcagtat
    54961 aaatctataa agtttgttgt tataacagat aacgaaatga taggtgttta taaaagagcg
    55021 tctaagacta gcaataaaaa agttaaaaag ggaaagaaaa tagaatcctt tttagattta
    55081 agtgttggag actatgtagt ccatgaaaat agtggtgtag gtagatacac aggaattgaa
    55141 caaattacag tcaatgctat taaaaaagat tatatgaaaa tagtatatca aggtggagat
    55201 aatctatatg tgccaataga ccagatggac aaagtacaaa aatatattgg tgcagaagta
    55261 gaaaaagtta agttaaataa gcttggaaca aatgagtgga cgaaagcaaa agcaaaagtt
    55321 aaaaaagaaa ttgaagatat gacaaaagac ttgattgagc tttatgcaaa acgtgaaaaa
    55381 atacaagggt ataagttttc aaaagataca ccttggcagg cagagtttga atcgttgttt
    55441 ccatatcaag aaacagaaga ccaattaaag gctatagaag aaactaaaaa agatatggaa
    55501 tcaagtaagg taatggatag gctagtatgt ggagatgttg gttatggaaa aacagaggta
    55561 gctattagaa gtatttttaa agcttgtatg gaccaaaaac aagttgctgt attggttcca
    55621 acaacaatat tggcccaaca acattataat acattcaaag agaggtttga aaattatcct
    55681 ttgagagtag aagttttaag taggtttaaa acaccaaaac aacaaaaaca gattattgaa
    55741 gatgctaaaa aaggattagt agatatttta attggaacac atagaataat atccaaagat
    55801 ataaatttac caaacttagg tcttgtagtc attgatgaag aacaaagatt tggagtaaaa
    55861 cataaagaag ctttaaagaa aattaaatct acagtagatg tacttacact ttcagcaact
    55921 cctataccaa gaacattaca tatgtcttta agtggaataa gagacatgag tgttatagaa
    55981 gaacctccac aagaaagaca tcctgtaata acatatgtta cagagagtaa ggaaagcgta
    56041 attcaagatg agatagagag agaattaagt agaggtggac aggtattttt tgtatacaat
    56101 agagttgaac acattgaaga aatggcaagt atgattcaaa aactcgtacc agatgctaga
    56161 gtggctgttg cacatggaag aatgacttct aaatcattag aaaatataat cctaggattt
    56221 ttaaataaag attatgatgt actagtctgt actacaataa ttgaaactgg tatggacata
    56281 tcaaatgcaa atacaatgat tatatatgat gcagataaaa tgggattggc tcaactttac
    56341 caattgagag gtagggttgg aagaagttca agacaaggat atgcatatct tttgtatgaa
    56401 aaagataaaa ctttaagtga gatagcggag aagagattaa aagctatcag agaatttaca
    56461 gagtttggtt ctggttttaa aatagcaatg agagaccttg aaataagagg agcaggaaat
    56521 attttaggtt ctcaacaaca tggtcatatg gcagttatag gttatgattt gtacgttaaa
    56581 atgcttaatg atgcaattaa aaaagtcaaa ggtgaaccta ttgtggagga aattgatgtt
    56641 gaaatagatt taagtgtaaa tgcatacatt ccagataatt atatcaaaga tgagttgatt
    56701 aaaattgaaa tgtataagaa aatagcttct attgaaaaca aagaagacat gttggatata
    56761 caagaagaac ttgaggatag attctctgat atacctaaac cagtccagac acttcttaca
    56821 atagcttata taaaatcgtt atgtaagata ttaaaaatag aaaagataag acaattaaaa
    56881 gatgaaatat tattagttcc aataacaaag tatagaacta aacagaaaat aggttataat
    56941 atagttacag aattagaaga attattagaa aagatgtgca aggtaaaata acttgtaaat
    57001 ttaagaaggg atgttttaaa tttgaaaaaa gtaataacat tggtaatagc tatgattttg
    57061 gtagtatctg tgactgcttg cagttctagt aaaggagaaa ctgtggcaac agttgaaggt
    57121 acaaagatat catcagatga atttaaaaaa actatagctc tttataaaga ttctatggaa
    57181 caaacttatg gaaaagatat atgggataag gaagttgaaa agggtgtaaa atacaaggac
    57241 aagtttaaag atttaattct tgaccaactt ataactacag aagtaatata ttctcaagct
    57301 aaaaaagata acttacttcc taaaaaagag gatgttgaaa aaagttttaa agaattaaaa
    57361 gacgctatgg gtaaagatga aaaatataaa gaacaactta agaaattagg tatagatgat
    57421 gagtttttaa gagaccaaca agagaaagat ttagcaatgc aaaactatca aagtaacttt
    57481 gctaaaaaga ctaaaatatc agatgaagaa atgaaaaaat actatgatac acataaagat
    57541 gaatttaaaa aagatgaggt agaagcttct catattttat tgaaaacagt agatgataat
    57601 aacaagccac tttcagataa ggaaaaagct gaagctaaga aaaaggctga agaggctctt
    57661 aaagaagtta aatcaggtga ggattttgca aaagtagcaa aaaaatattc acaagatact
    57721 tcagcaagtg atggtggtaa attaggattc ttttcaaggg gtcaaatggt tgctgaattt
    57781 gaagatgctg ctttttctat gaaaaagggt gaagtatctg atttagttga aactcaatat
    57841 ggataccaca taattaaagt gacagacaga ataaatgagc aaacatcatt tgaagatgct
    57901 aaagaaacta taaaagacca actgttgaaa aataaatatc aagaacaaat agaaaaatta
    57961 actaaagaag ctaaggtaga aaaagatgaa aaagtaataa ataaaatcac aatctaagac
    58021 ttaaaaaaag agtaatatgc ttaaaaaagc tatatctgga taagatatag ctttttttgt
    58081 atatttttct taacaatggt aaaaataaac ttaaagtaat ttatggaggg attaaaaaat
    58141 atgaaagcaa caggtatagt tagaagaata gatgatcttg gaagggtagt tatcccaaaa
    58201 gagataagaa agacattaag aattagagaa ggagaccctt tagagatatt cacagcaaaa
    58261 gatggagaag tcatacttaa aaaatactct ccaataggtg aattaaatga attttcgcaa
    58321 gaatatgctg aaacattagc tgaagtacta ggatatggag tgttgataac agacttagat
    58381 tctataatag ctgtatctaa gcttcctaaa aaagattaca aagaaaaaag tataagtgat
    58441 gagttagaag caataataag tgaaagaaca gtaaaatatt caaaagataa aaacatttta
    58501 ccattattca aggaagacca aaaagaatat actagtcaag ttatcatgcc tataattagt
    58561 gcatctggtg actgtatagg ttcaattgta gttgtttcaa aggataaaga tacaattgca
    58621 gaaagtgaag aaaaatcttt aaaaattgct gctaactttt taggaaaaca agttcaataa
    58681 ttttatcata aagacctttt acatgaaggt cttttgaagt ttttgtgtaa aatattgaat
    58741 atagcattaa aaatatggta tattaaagtt tgttatataa acagtatgga ggttatgtta
    58801 tgaacaataa caaaaataaa gactcctttc taaaaggagc ccttatactt gggctagcag
    58861 gtgtaatcgt aaaaataatg ggtggatttt ttaggattcc ccttggaaac atgattggtt
    58921 cagaaggaat gggatactat caggctgctt atcctgtgta tactctattt ttaacattag
    58981 ctactgctgg atttccaaca gctgtggcaa aattggtttc ggaaaaagtt gcaattggaa
    59041 attttaaagg tgcaaataag atatttaagg tatcacatac agttttattc attaccggta
    59101 taatatcatt ttgtatatta ttttttggag ccgactacat agtaacaaac gtaatgaaaa
    59161 atccaggtgc gttatactct atgaaagcca ttgctccagc attactattt gttcctgcaa
    59221 tgtctgcata tagaggatat tttcaaggga gacaagatat gactaagatt gctgtgtctc
    59281 aagttgcaga gcaatttttt agagttgtat taggtcttac tttggcctac ttacttatga
    59341 agagtctagg tcagactttt ggtgcagcag gtgctatatc aggggctaca ataggttcaa
    59401 tagcatctat gctttatttg gtgtttgctt atatgctagg gagaaaagag cgtagagcag
    59461 agatagatgc aagccaaaga tttaaagatg aaagagtgtc ttatattttt aaaaagcttt
    59521 taactgttgc cattcctata acaataggag catcagtaat gccacttgta aatatgatag
    59581 ataatgttat tgtaataaga agacttatgg aagcaggatt tacatacaaa gtggcaaatt
    59641 caatgtttgg tcaattaaca ggtatggcaa tggccacaat aaatttacca gcagtcataa
    59701 caactgcaat gagtatgagc ttagttccag caatttctaa agcatatgca ttaggaaata
    59761 agtcaaaagc tagaaaagat actaagagtg cagttaaggt aactttactt atagtattgc
    59821 cttgtgcgtt tggtatggct tctttagcaa taccaataat gggtctttta tttccacatg
    59881 aaccatcttc tgtaggaact attttgttta ctcttactcc atgtgtatta tttttaggat
    59941 taatacagac attgactggt ataattcagg gaatgggaaa accaatagta cctgtaattg
    60001 ctttatgtgt tggtatgcta tgtaaaattg taataagtta tactttaaca ggtataccag
    60061 atattaatgt actgggttca gcatttggta cagttacagc atactttgtg gcagccatga
    60121 ttaacttact atatgttaaa aaacacatga atgtaaactt ttctaaaaaa gaatttataa
    60181 taaagccatt tataacagtt atgacaatgt ttataatggt taagttgagt tatggtgctt
    60241 tagttggatt cttaggaaac agcatatcta caataattgc aatatgtgtt ggtggaattg
    60301 tatatgtagt agtaatactt ggaataggtg gaattaaaaa agaagagatt ctaactatgc
    60361 caaaaggtga taaattatat aaattgttaa aaaaagttaa acttataaga taatatagga
    60421 atatatatgc aaataaagga aatactatac aaatagtaaa tctccttatt tgtataataa
    60481 tataaaaata aagtgaaatt tgctaatagg agtgatgtta tgggtaagat aagtattgta
    60541 ggtcttggac caggagacta ttctcttata agccaaggtg tgttagaatc tttaataaat
    60601 agccctaaag ttttttttag aacagagaaa catccaataa ttgataaact taaagaaact
    60661 atacaataca cttctttaga ctacttttat gaaaaagagg aaaattttga taatgtttat
    60721 ttgaaaatat ctgaatttat catagaagaa tcagcaaagg gtgacctagt gtatgctgtt
    60781 cctggtcatc caagagttgc agagaagact gtaagtataa tagagagatt agccaatgaa
    60841 aagcacatag cagtagaaat attgccttct atgagctttg tagacgctat gtttaactat
    60901 ttggctatag acccatctga gggatttaaa ctggtagatg cttttgaaat agaaaattca
    60961 tatatagact tggatacaag catgataata actcaggtat atgataaatt tatagcatct
    61021 aatgtaaagt taaaacttat ggaacattat gactataatc aagaagtatg tatagtaaat
    61081 ggagcaggtg tcaaagattt agaaagtaaa aagtttataa agctttgtga attagacaga
    61141 aatgaaaact tttttgacta tttaactagc ttatatatac ccaaaagttc taaaaagatg
    61201 tataatacag tacatgactt agaaataata gttaatacac ttagaagtcc atctggatgt
    61261 gaatgggata aaaaacaaac acatcaatca ttaaaaaatt ctgttataga ggaagcatat
    61321 gaactttgta atgcaattga taataatgat atagatgaaa tggtagaaga gttaggtgat
    61381 gttcttttac aggttatatt ccattgtcag ataggaaatg aggagggcta ctttgattta
    61441 aaagaagtag taaatggcat atgtaaaaaa ttaattcata gacatcctca tatatttagt
    61501 ggtgcaaaat tagatatgtc taagtttgag aaaacttggg aagaattaaa gaaagaagag
    61561 aaaggcgaaa gtactataac agatggcctt agaaggatac caaaacattt accagctctt
    61621 atgaaggcta gtaaagttca acataaagca gcacttgtcg gctttgattg ggacaatgta
    61681 gaagatgtat ttaaaaaaat tgaagaagaa tatcaggaat tacttgacga acacagggtc
    61741 gggaatataa aatacataaa ggaagagcta ggcgatttat tattttcgat agtaaatcta
    61801 gctagatttt tagacataga ctcaggagaa gccttgaact gtactacaga aaaattcata
    61861 aatagatttg actttataga aaaaagtgca atgaacttga ataaaaaatt agaagacatg
    61921 acacttgaag agatggatga gttttggaat caggctaaaa aacaataaaa ttgtggaagg
    61981 aaatttgtca aaaatctaga acttttatca caaagataga agtctatatt ataaacattt
    62041 ttaggaggta aatatcgtga ataaagctga attagtatca aagatggcag aaaaaagtgg
    62101 attaacaaag aaggaagcag aagctgcgtt aaacgcattt atgagttctg ttcaagatgc
    62161 actagtaaat aatgaaaaag ttcaattagt tggatttgga acatttgaga caagagaaag
    62221 agctgctaga caaggaagaa atccaagaga tccagagcaa gttatagata taccagcttc
    62281 taaagcacca gttttcaaag ctggaaaagg attaaaggat ataataaatg gataattaga
    62341 aatcttgtga aaaagtgtgg ataaatttgc cacacttttt ctatagaacc aaggaaggtg
    62401 ataattatga gattagataa atttttaaaa gtatctagga ttataaaaag aagaactgtt
    62461 gctaaagatg catgtgataa agggattgtc actataaatg gaaaagttgc taaatcttct
    62521 tcagaggtga atattggaga tacattagaa atacaatttg gagagaagaa gatgaagttt
    62581 aagataaatg aagtaaaaga gcatgtatta aaaaatgatg caaaagaaat gtacgaaatt
    62641 ttagaataaa attaatagtc ctctagtata ttaatagtag tattattgaa atatttactg
    62701 gggggatatt atggaacaga acataacttt gaaagataga tcaaagctgg ttatttcggg
    62761 agtcgagcac atatactctt ttaatgacaa aagagtagag ctcaaaactt ctgtaggcga
    62821 gatggtaatt gaaggcgaaa acctagatat gagcaagcta agtatagacg aaaatataat
    62881 tagcatagat ggaactataa attctatggt atatgcaaag cctaaaaagc cacaagagag
    62941 tttcttgaaa aaggtattta gatagatgat accttttact caagatgtaa gcatttttta
    63001 tgctactatt tatggtggaa tactcatagg ggtgttgttt gatttttata gagggctaag
    63061 agggaatttt aaattcatca attattttgc tataatcttt gatgtattgt tttggtttct
    63121 agctacggtt ataatattcg taacaataaa ccttacagaa ttttttgatt taagatatta
    63181 tcattttgtg gctttgttta ttggttttat tttatactat aacaccataa gtaaaattgt
    63241 tttatcaatt atcaataaaa taattcgttt tgtgagaaat tcttttaaaa aagttacaca
    63301 ttacatagtc agttttttaa ataatttgta ttacgttata atctattcac tacacctact
    63361 atttgatatt atattttata taccaaacat atttatagca acaagaaaaa gtataaaaag
    63421 aaaatcaaat aaaaaattaa agaacaagaa aaaatcaaaa cctaagaaga aaaaaaataa
    63481 aactaaaaaa agggtgtagg aaaaatgaac ttaagaaaaa aattttcagg acagattatt
    63541 gttatcagtt tatttttagg aatatcaatt tttagtatga tgacaggatt tgtatttgag
    63601 tatacaaaag ctaaggaata taaaaaagaa atagcaagtc taaataaaca attaaaaaag
    63661 actgaaatac aaataaacag cttaaagaaa gatgaaaaat catatgaagg agacttagag
    63721 gatatagcaa gaaaaagatt gaatatggta aaaccaaatg aaacagttta tgtagacata
    63781 aatcgttgat taaaacttgc taataagttt acagatgtat tgattttaaa atttaagatt
    63841 taataaaaaa gtcattcagt taaggatggc tttttgtttt tattgaggag ggaatttcat
    63901 aatgaaagta ggagctatag atattgggac aaactcaatg agattattga tagcagatta
    63961 tagagatggg aattttataa acagaaaaaa atttgttaat acaactagaa ttggttatgg
    64021 tgtggatagt aaaggatata taaaagaaga tgctatcaaa agaaatataa aagcattaaa
    64081 agaattttct gataagtgta atgatgaaaa gtgtgaaaaa atttattgta tggggacatc
    64141 tgctcttaga gacagtaaaa atggagatta ctttgttaaa ttagctaaag aagaaactgg
    64201 aatagatgtt gatatagtta cgggaataga agaatcaaat ttgggcttta agggtgtttt
    64261 agaaggaata caaggtgatg atactattat tgttatagat attggaggag gttcaacaga
    64321 atttattgta ggtgattcag aaggaattaa atttaataaa agtgagaatg taggtgctct
    64381 taggatgaca gagaggtttt tgaagcacga tattattgaa gatgaagagt ttgaagctat
    64441 gagttcattt atatatgatg agattgacaa aacgttaaat catataaaag acagaggatt
    64501 aaaaactctt ataggtatag gaggtacgat tacatcatta tcagcaatga atcaagaatt
    64561 agagatttac tctatggaaa aaatacataa tagtaaaata cacaaaaaag aaatagaaga
    64621 aattctacaa aaattaataa agatgacatt aagtgataaa aagaacttaa aagggctaca
    64681 agaaaaacgt gcggatatta taactgctgg tgtaaaaata ttgaatataa taatggaaaa
    64741 attagaaata gaagaaataa ccgtaagtga atacgataat ttggaaggct taatatgtca
    64801 aaagtcaaaa aaaatgtatt aatatttttt gatttttaaa accgattatg acaaaaaaaa
    64861 ttactcctct ttgttacaat tcttaatata aacaaaagag gaggtttttt tatgcaaaga
    64921 agtgtagcag ttgtgaagaa taagactgta aaaccaaatg tcataaaatt aataagcgga
    64981 tatattgatt ttactacggc ggcattcgct gtgatgggat ttttacttag taggtctatt
    65041 atagtagact ctgtagctcc tttaggaatt gcctttttta tatgtgcatc aaagattgat
    65101 aagtacaaga tacctgtatt catatcaaca ttattaggaa tattgttatc atctaatgat
    65161 tttggaaatg tagcaaaata tgctgtgtgc cttacaatat ttatggctat gaataaaaaa
    65221 ttaaaattat cagattcaat tgctaaggtt gcatttatag gtgcaataat actacttcca
    65281 atctccatgg gacaagcttt cttttcaaat aggtatgtat atggtcttct tatagcagga
    65341 gtagaagcaa taataatgtt tatatctata tatgtgtttt cttatgggat aggtttaatg
    65401 gccaatgtca acaataggat gtctgtacgg acagaagaag ccatatcaat aagtttactg
    65461 ctaaccttta gcataatggg aataggagat atatctctgt ttggaatatc aataaggacc
    65521 attttatcga ccgtattgat attgctgacc tcaatagtag gtggagctac catgggagca
    65581 tctagtggtg taattattgg tgtagcatcc attttaaata atatgacatc agctgtttat
    65641 atggggatat attctttttc aggattaata agtggagcat ttaataaaat aaataaatat
    65701 ttctgtatac taggatatat tctaagttgg acaataatat acctatatac ttctggtatt
    65761 acttctaata tgatgcaatt aagagatata ctattaggtt gtttgatagt actagtattg
    65821 ccagagagat tatttaataa gattgaaaaa ttaataaaaa gtaatgtggc ttcaaatgaa
    65881 atcgtatacg attatattat gagaagcaaa aacctaacta atagcagatt gaacagtatt
    65941 tataaaactt atgatgacct tgcagataca tttgataaga taagagaaaa agacaaagtg
    66001 ctagaccaaa gagacatagc taatgtaata gatatgattc ataatgatga atgtaaaagt
    66061 tgtagtatga gaagaatgtg ctgggagtca agatttaatc atacatacac tatgatatat
    66121 aacattcttg aaaaaattga ggagaaaggg gagttaagtc taaacgatat acctaaaaat
    66181 tttagaaagg aatgtatgaa accagagtca atagtgaaaa tatcaaatca ctattacaaa
    66241 atgtttgtat tagattatga ttggagtgtg aagttttcag aaagtagaaa gttaatagca
    66301 aatcagataa gaagtatttc aaaatccatt aaatccttat ctcaagattt agaaggcgac
    66361 ataatgctag atatagaaaa ggaaaaaaat atatatgaac agttagaaag atatgatata
    66421 acagttgata aagtaagtta cttaacaaaa agtaacagtg agtttgaaat atcaatagaa
    66481 aagaaaactt gccatgatgg atgtatgtgt gaagataaaa ttgtaaatat aatttcagac
    66541 ctagtagggg aaaatatgtc tgttagaaaa ataggatgtc actgtttagg aggtaaatgc
    66601 aaggcaacat tcgttaaatc tcaaaaatat aaggctgtta cagaagtttc agcaatgtca
    66661 agggatgggc atatcctttg tggagacaat tacacataca tggagataaa tgatggtaaa
    66721 tacatgatgg ctataagtga tggtatggga aagggtaaaa aagcatatga agaatcttct
    66781 gccactattg atatactgga aaaaatgata gatgcaaaaa ttaaagatga gatagtcatt
    66841 gatactataa acaatatgtt gttgttaaaa tcttcagaag agatgttttc aactctggat
    66901 ttgggaattt tagatttaaa acgaggttgt ttagaaacta taaagatggg agcgtgttct
    66961 acttatataa aaagagagga tggagaagtt gacttaatat catcatcatc attacctgtg
    67021 ggtatattat cagatgtaaa aattgataga aaaaatgtaa aagttaagga aggagactat
    67081 gttataatgg tttctgatgg aattgtagat gcaggaagaa ataacaattt aggagacaat
    67141 tggttaatat acttcttaaa gaatatagag actacaaatc caaaggaaat ttcaaattta
    67201 atattggata gagcattaga gttacaagcg ttacaaatcg aagatgacat gactgtttta
    67261 gttacgaaaa tatgtacaaa ataaggttta caagattatg tgtataagat gtggataact
    67321 tgtgtataat atgttaatag acttttgaaa aaagtatagt tattaacaaa aataacatat
    67381 aaatcaacaa aatttgttga taagtatggc agaaatgtta ataaaatgta aaaaaagaaa
    67441 aaacaaaagc tattatcaaa agagattcat gttgaaataa ctaaatttct aagtaaagaa
    67501 aacctgtgaa tatgttgatt attatgtgga taactattaa ttcgatattt atttatatag
    67561 tatgaataat tgaataatat atctaaaaaa agccatccta ttattaagta aacttattga
    67621 aaggatggct ttttatgaat agaaaattgt gcaaagcaat aataccttta tttatttcta
    67681 ttttttgcat gttaataata agtataaaag ctgaccaagg atatcaaaag aataatgaca
    67741 gagcaattac tgtcatgaat aataatgata ctgaagatga tgctgaaaaa aaacaagaaa
    67801 tagactatga aaaaacatgt tggaatttgc aatctttgtt taaaagtgat gaccaatgga
    67861 aaaaagaact taagagtttt gataaagata ctaaagagtt gaaaaattac ataggtaaag
    67921 taacaaaatc gccaacacat ttgtcttttg ccttgaacat taaagaaaaa cttgatataa
    67981 gactaaataa actttctgcc tatgtaaaat taaaacaaga tactaataaa aattcgtata
    68041 agtacttaga tatgaatgat agtatgagta aatcctatgg gaattatatg gggatttgtt
    68101 cagatttaga gttagaaata ctaaaattat caaacaaaga ttacaagaaa attatttcaa
    68161 ataaaaatat aaataggaaa tatggtgcat atttaagaga tataagaagg aataaagtac
    68221 attatttgga tgataaatca gaagatattc taagcaaagt atcttcaata agtagtcttc
    68281 caagtcaagt gtatgaatta tttagaaata tggatagaaa aactaattta acaccagctc
    68341 aatatgcgag tgaattagag tcatcagata gagaaaatag aaaaaaagct tatcaagatg
    68401 aacttataac ttacaatgat aatataaata caattgcagg tttaattact ggtcaagtta
    68461 aaaagaatat tttttattct caggaaagag gttatgagtc ttctttagaa atgtacctgg
    68521 aagctgataa tgtagatgaa aaagtataca ataatttgat aaggactgta aatagtaata
    68581 tggacagtct acacaaatat atagatttaa gaaaaaaagt attaaaatta gataaggttc
    68641 attcatatga tatgtttgtg cctatggtta aggctgttga taataatatt aattatgaaa
    68701 aggcacaaag tatagtatat tcagcgttgt cacctttagg aaaagaatac aatgatgtag
    68761 tatataaagc tttcaatgaa aaatggatag atgtttattc acatgaaaat aaagtaagtg
    68821 gtggatactg cttatctgtt tatgaaaatc atccatatat acttttaaat tataataatt
    68881 cattaggttc agtttcgact ttatcacatg agcttggaca tgctgtatat gaatacttaa
    68941 gttctaagaa tcagaattat tttaattcaa atccgtctat atttactcac gaagttgcat
    69001 ctacaacgaa tgaagcatta ctttacgaga tgcttataaa agaagctaaa ggcaatgatg
    69061 aaaaagctta ttatataaca cagtatttag acttgataaa agatactctt tatacacaaa
    69121 ctatgtatgc tgaatttgaa aaaactatac acgagttagt agaaaaagga aaaagtgtaa
    69181 acgcattagt attaaatgat gtttggggac aacttcttaa aaaatattat ggacaaagct
    69241 atgaattaga ccaattatct aaggtcggat gggctagaat cccacatttt tataatagtt
    69301 tctatgtcta taaatatgct acaggttgta gtgcaggagt aagttttgcc caagacatcc
    69361 taaagaatgg ttcagataac tatatgagct ttcttaaaaa gggaagttca gattatccaa
    69421 taaacttgtt aaaatcaagt ggcataaatt taactaatac aaaacccata gaaaatacaa
    69481 tcaaaaaatt tgatagttta gtagcagaac ttgaaaagct attataaaca ttattgtaat
    69541 ccacatggta aatatatcga attaatgata aaatatacta aaagtttaaa gtcctatcaa
    69601 gataggactt tttatttatt aattagtggg agatgattct atgcaagtta aagttaaaaa
    69661 ggctgtaata ccagcagcag gtttaggaac tagatttttg ccagctacaa aggcacaacc
    69721 aaaagagatg ttaccaatag ttgataagcc aactctacaa tacataatag aagaagctgt
    69781 ggcctcagga atagaggaaa tactaataat aacaggtaga aataaaaaat ctattgagga
    69841 ccactttgat aaatctgtag aattggaact tgatttagag aaaaaaggta agaaagaatt
    69901 gttggaggta gtacaaaaca tatctaacat gattaacata cattatataa gacaaaaaga
    69961 gccaaaaggg ttgggagatg caatttattg tgcgaggcat tttataggtg atgagccgtt
    70021 tgcagtaatg ttaggggatg atattgtaga taatgatgta ccttgtctaa aacaactaac
    70081 agatgcatat gaggaatata gaactacaat attgggtgtt caaaaggtaa atcaagaaga
    70141 tactaataaa tatgggataa tagaagcaaa aaatatagaa ggtagagttt acaaggtaaa
    70201 agacatggta gaaaagccag agtcaggaaa agctccttca aatattgcta ttttaggtag
    70261 atatataata actcctgaaa tctttgatat tcttaaggat ttaccaccag gtaaaggtgg
    70321 agaggtacaa cttacagatg ctttaaaaat attatctaag aaagaagcta tgtatgcata
    70381 caattttgaa ggcaagagat atgatgttgg ggacaagcta ggatttttag aagctactgt
    70441 tgactttgct ctaaagaaag aagaccttaa ggaagatttt ataaaatatt tgaaacatgt
    70501 atgtagtgaa tttgataaaa ataacaatgt gttatacaat aatacagatg aaaaaataga
    70561 tttaattgaa gtcaatgaag ctagagaact tgaaattcaa aaataattaa tgaaaggtga
    70621 tgtatggtgg caaaatcaag tcagaaaaga attaatagaa taatagctgt tgggattgtg
    70681 ggaatcctcg taataacgag tataacagct gttttgagta tgattgcaac tatgtaataa
    70741 gataaatgac agcagttgat atacataaat ataaaaacca tatataactt gatgtagtca
    70801 aaaacttaca atattttagt tatatatggt ttttagaatt tataaatgta aaaaaaaatt
    70861 tttataata
//
LOCUS       DAEPKC010000009        62063 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.009, whole genome shotgun sequence.
ACCESSION   DAEPKC010000009 DAEPKC010000000
VERSION     DAEPKC010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 62063)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 62063)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..62063
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.009"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..1044
                     /locus_tag="KR294_000672"
     CDS             <1..1044
                     /locus_tag="KR294_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH0238788.1"
                     /translation="DTKIIEYVEEILEVINNQYTFDLRNDSVLFDDLVLHFKSILNSK
                     SYNLNKVNPLINTIKSNYPLAFEITLNAIEKVFKNSIYSLTEDEIGYVSLHIGAGIER
                     FFQSNIKCKNVVLVCGSGYGSSRLLEVQLNKVFHDKINILQCLSFNQFLASELSDVDI
                     IISTIPLNHDSIPIVLVDLKLLKKDIENISKSITNNSHIYSNLLDNFFDKNLFIVNPK
                     IKDKDELIKLMCNKLTQSEIVFPSFAESVFYRESLSSTNIDDFLAIPHPMELSSIRTK
                     ICISILDEPIYWSEDSTVKLIMMLAINKDDYIKINSIYDILLKIIHDNDIRDSISNCN
                     DFDNFLSIIKSIV"
     gene            complement(1304..2065)
                     /locus_tag="KR294_000673"
     CDS             complement(1304..2065)
                     /locus_tag="KR294_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH0238789.1"
                     /translation="MEYTVQKLSKLAGISTRTLRYYDEIGLLKPLKINSSGYRIYGQN
                     EVNKLQQILFYRELGINLENIKNIINSPNFDSLSALKEHHNKLLAKRKQIDLLIENVT
                     KTIALKEGKYTMTDIEKFEGFKEKMIDENEKNYGTEIREKYGKDIIDTSNKKLKNMSK
                     QDYENWQNLNIEIISKLKKAFKTGDASSELAQEVAKLHHKWLSYTWNTYSKEAHSSLA
                     QMYVYDERFTSYYDREQPGLAKFLRDAIVIYTRDK"
     gene            2284..2760
                     /locus_tag="KR294_000674"
     CDS             2284..2760
                     /locus_tag="KR294_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HBH0238790.1"
                     /translation="MNLKRSNEKREEYRRMYSDKESFLSLIQNFTSVSIAKELTLKNI
                     ELETSFICEYKGKEVDIIYKVFSKSGKVSHYIVLEFQTEMDTEIVPRLKSYREQIWKS
                     FIMKKSLEEIEDKNFKLPKVIPVVLYSGPERLSRKKGILDIVESISEFSNNSSMKN"
     gene            2858..3010
                     /locus_tag="KR294_000675"
     CDS             2858..3010
                     /locus_tag="KR294_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate translocator"
                     /protein_id="HBH0238791.1"
                     /translation="MRNNKSKVLLGILCLATGMAVILSMLLPGWIWSALTALILIGCG
                     ALLFFC"
     gene            complement(3170..3358)
                     /locus_tag="KR294_000676"
     CDS             complement(3170..3358)
                     /locus_tag="KR294_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HBH0238792.1"
                     /translation="MAKVCSVCGKGKVSGNQVSHSNKHNKRTWSANLRSVRAIIDGAP
                     KRVKVCTRCLRSGKIERA"
     gene            3719..4069
                     /locus_tag="KR294_000677"
     CDS             3719..4069
                     /locus_tag="KR294_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBH0238793.1"
                     /translation="MSAKVTNQYGNIEIDNQVIAQVVYRAAMESYGLVGLAYKSKGIV
                     ELLKGENATKGVRVEEVEEDAIAIELYVIIQYGTNISTVANNIIDRVKYVVEKMTGVR
                     VTRIDINVQGIRVK"
     gene            4088..5731
                     /locus_tag="KR294_000678"
     CDS             4088..5731
                     /locus_tag="KR294_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HBH0238794.1"
                     /translation="MIQYIDGKRLREMFISGANNLQNNKELVDKLNVFPVPDGDTGTN
                     MSLTISYALKELAKVENDNISDIGKALSKGSLMGARGNSGVILSQIIRGIAKSIEGKS
                     KLSTEDLAKAFKNGSDTAYKAVIKPIEGTILTVVRESGEFAIKTAKKEKDVVKFLSML
                     VKESNSSLERTPDLLKNLKEAGVVDSGGKGLVLIYEGMLASIKGDNIEIKNVDLDTNI
                     STSMDFAKSTTSTDDIKYCYCTEFILESSKVEDTKIRDIMMAYGDSLAVVGDDGVIKV
                     HVHTNDPGNVLQEALKYGQLLTIKIENMKLQHENTLLDVEEKKENDSEPLEEEKEFGF
                     IATSMGEGLANIFKDFGVDHIIEGGQTMNPSTEDFMNAIKHINAKNIFIFPNNSNIIM
                     AANQAKELSDKNIIVIPTKNTPQGFAALVTFNGELSEDENKEAMMNALNSVKSGQVTF
                     AVRDTVMNEIDVKEGNIIGIAEGNLLSAGDYVDEVTSNLIEKLVDEDTAIITLFFGED
                     VTESQANELRTSLEEKFEDVDVELYYGGQPLYYYLISVE"
     gene            5812..7869
                     /gene="recG"
                     /locus_tag="KR294_000679"
     CDS             5812..7869
                     /gene="recG"
                     /locus_tag="KR294_000679"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HBH0238795.1"
                     /translation="MDLYKDVQYVKGIGPKKADKLNKLGIFTLKDLLYYFPRQFEDRN
                     NLKKIAQLEDGEKVTIKAVISSINTFSPKEGMTLTKIDVKDETGSAKLVFFNKSYIKN
                     TFRPGDSILVFGKVKKKFNNLELTSCELEYLTNSPKNTCRFMPVYQLTYGVTNKEIMS
                     IIRTVLEDKELIIQEYMPQRIIEKYRLCSIDFAVRNIHSPSSKESLKIALYRIVFEEL
                     LILQLGLFVFKSGRNKEDGIKFETSKDLKKIISALPFKLTKAQNRALDEIIQDMNLEK
                     IMNRLVQGDVGSGKTVVALLALANCVLNGYQGALMAPTEILAGQHYISLTESLKDFGI
                     NVGLLIGSLTKKQKDTVLEQIKNNEIDILIGTHALIEDKVEFNNIGLVITDEQHRFGV
                     MQRSKLSLKGANPDILVMTATPIPRTLALILYGDLDISIIDELPPGRQPIETIAIEKS
                     KRDRAYNNLVRREVESGRQVYIVCPLVEESEAIEAKSAVELVEELRAEYFHDLRLGLL
                     HGKMKSSEKDEVMRLFKDKEIDILVSTTVIEVGVNVPNATLMIIENAERFGLAQLHQL
                     RGRVGRGSHKSYCVLIYDSKTDVCRQRMAIMEETNDGFKISEKDLEIRGPGEFFGTRQ
                     HGLPELKVANLFKHIKILKLAQQEARYILGEDNNLQLKENMALKKEIIDKFKDTLKEI
                     SLN"
     gene            7928..8482
                     /gene="rsmD"
                     /locus_tag="KR294_000680"
     CDS             7928..8482
                     /gene="rsmD"
                     /locus_tag="KR294_000680"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HBH0238796.1"
                     /translation="MRVISGKARGLKLNTPKNEDVRPTTDRVKESLFNMINSYIMESE
                     VLDLFAGTGSLGIECLSRGAKSCTFVDISKESIDIVKSNIKKARVESESIILNLDFKT
                     AIDKLKLQNSKFDIIFMDPPYYKNMFIEAIEKIDNSNLLNEDGIIVVEHDTNDLFPDK
                     ICKLEKTRDKKYGNTTLTFYKMEA"
     gene            8484..8981
                     /gene="coaD"
                     /locus_tag="KR294_000681"
     CDS             8484..8981
                     /gene="coaD"
                     /locus_tag="KR294_000681"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HBH0238797.1"
                     /translation="MENKPRKAIFAGSFDPITNGHLDIICRASKLFDELQIGVLNNPN
                     KKGLFSFDERVKLIEKSTSHLNNIKVVTFDGLLINYCQENGIGALVRGVRSGADVDYE
                     LQMAHMNRELNPDIETIILPSCTKYSFISSSLIKEVLLFDADIKNLVPKIVLEELKKK
                     TSGGN"
     gene            8985..9509
                     /locus_tag="KR294_000682"
     CDS             8985..9509
                     /locus_tag="KR294_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0238798.1"
                     /translation="MKIDLEMIELFEQLEEIFRSASTIPFSHKCTVDKDEVLAIINDI
                     RTLIPEEVTQAVWINKERNKIISQAKQDATNIVEQAKKEAERIQQEYQDNIEELKKNS
                     EDVVKAYVESSEPVVQADQRAKDIVDRAERIANEIRIGSIEYAEDVLSSVEYNLREIL
                     EEVKRDKAELRPKK"
     gene            9853..11772
                     /locus_tag="KR294_000683"
     CDS             9853..11772
                     /locus_tag="KR294_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBH0238799.1"
                     /translation="MKERAKKILDFIIKNNNVTSQELQEKFNVSKRTIYYDILAINEQ
                     LGKSGNIKNVKHKFIFEGNLCDARKIISTEEDKFLDSDYRKTFILNKILLGEKISIEK
                     LTNEMLLSKNTVVQTITDVKKYLQTMGLRLEYKGKYKIIGDEYVIRELFLIIVQENVL
                     EINSISEEVSSFDTKGHIKLTDYSLLNLTKFVEFLNKRIRDGKTLYSYKYLNEAKKIS
                     YFSNCKELLCEEANENEQAYICTYISSLPSLNSEVKEDVVEEYVDKLIDKFEVNTAIK
                     LESKHEFKKNILRHLHSSYNRIRFKFPIRNPMLDETKYKHESLYKIIKSIIENEEEFP
                     VFEGIREEEIGFIAAYFGGYLRGSRDNGLRRNKVLLVCPNGLMVSKSLEIQLYKYIPT
                     IEIVGIVSIKQLKEVNVYYDYIITTIDIQNVNNVIVVNPLLTSSDVQLLMNKLISVKE
                     NEKYFNLELIIQAIRKNGVINNEEALKADLLNIIHKIDEGEMYQPMLKELINAERVNI
                     IKNVRDWKEAIKIASKPLLEDNSIEELYIENMIKSVEKYGPYIVLADRFALPHASSKE
                     GVNKLAMSLLIVEDEVDLLGKPVNIFMVLAAVDNTTHIRALASLSEMMYEEENVKLII
                     NGDKSSIIELINKQN"
     gene            11785..12072
                     /locus_tag="KR294_000684"
     CDS             11785..12072
                     /locus_tag="KR294_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH0238800.1"
                     /translation="MKILAVCGFGVGSSMVLKMTIQKALKQLGIECEVENTDINSARG
                     ADCDCIFTSQELLNELKGTCNVDVYPVKKYMDLAEVTEVVQTFLSDKNDKK"
     gene            12832..12945
                     /locus_tag="KR294_000685"
     CDS             12832..12945
                     /locus_tag="KR294_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013483530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBH0238801.1"
                     /translation="MIMGRHLWNPSYFVATVLENTEEQIGKYINNQKKQVK"
     gene            12947..14065
                     /locus_tag="KR294_000686"
     CDS             12947..14065
                     /locus_tag="KR294_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBH0238802.1"
                     /translation="MIVVEKAYKFRMYPNKKQQELINKTFGCCRFVYNKYLAKRIEVY
                     KNDKETFTYKQCSSDLTNLKKELKWLKEPDKFSLQNVLKDLDNAYKKFFKEKAGFPKF
                     KSKKINRFSYKTNFTNGNIMYCGQHIKLPKLGMVKIRDKQVPQGRILNAAISKEPSGR
                     YYVSLCCTDVDIEAFENTNNQIGLDLGIKEFCISSCGEFIENPKYLKKSLNKLAKLQR
                     ELSRKTIGSLNRNKARLKVARLQEHIANQRNDFLQKLSTKLIKENDIICIEDLQVKNM
                     IRNSKLSRLISDVSWSEFIRQLEYKANWYGRQIVKVGKFFASSQICNKCGYKNEEVKD
                     LNIREWICPSCNETHDRDINASINILKEGLRLITIQNK"
     gene            14216..15433
                     /locus_tag="KR294_000687"
     CDS             14216..15433
                     /locus_tag="KR294_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HBH0238803.1"
                     /translation="MLIGLIAAFGLVLQKKKASDVIKGSLLAAFGIIIMETGTGMLVS
                     SIAPINGAFQSISGGAVTKGLSDVTFTASYGGIIGLAMFAGLAIHLMIARFTPIKTIF
                     LTGHMLYWFPFIFVASGVEAGLNGGVLITFAAVLSALYWSIMPWLLRKYVFDVIGDDS
                     FTLGHPSGCLALISGFVAKLVGNKEKSTEDINIPQSLSFFREISISGGMAVFLMFIVV
                     GIVIPGAFKDSNEFIGTYAIKQGLSFGAGLIIMLHGVRMLINQIMPAFQGISEKVVPN
                     ALPAFDCPILFNYKPNAVLIGFLVAMLTSTAMILIYNYFNVFNLLLIPLVITSFFECG
                     AAAVIGESQGGIRGAIIGTAIAAIFMVVLVGISAVIYSGTIQNWILIFGGNDLSLFGI
                     ISRFIGSLFGGIL"
     gene            15436..16176
                     /locus_tag="KR294_000688"
     CDS             15436..16176
                     /locus_tag="KR294_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBH0238804.1"
                     /translation="MKFKYIDEIRRLIDIIENEEKVNMEKAVQIFVEAIESKNAIFSF
                     GASHAGILTEELFYRAGGCVLINPVFAKSLMLDTAPITHTSKMERLEGYGTALADKTP
                     IKKGDVVIVHSVSGRNPVSIEFAMKAKENKAIVICITNLSYSKSVSSRHSSGKKLYEV
                     CDLVIDNHGQKGDACVEIDGLNQKVSPTSTVIATTVMNSIIAQATQELVNKGLKNPPI
                     FYSANIDGGDELNKKIFDEYKSVIHYEY"
     gene            16499..17809
                     /locus_tag="KR294_000689"
     CDS             16499..17809
                     /locus_tag="KR294_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HBH0238805.1"
                     /translation="MKKENKMEGIKVGMLKKLCSLAMVAIMTTTLITGCSSGNGKDSK
                     KDGEKEKLVLWMPPVENNMKEVWDPILDKFEEKNNCEVDLQIIPWDNYSEKFATAISA
                     GEGPDVGYMYAEMYPQFIESGAVEDLTNYATKEDKEQSIYIKTSEMMGGMYGMPFQAA
                     NPGVLYYNKDILEKLGEKPPKTWEDFKRICKKATQDTDGDGKIDQWGLAQGWGAKTFG
                     NLNWNWYPYLWQAGGDIFNDDLKSVKFNDKSGLEAANFLKELQAYVPEDSLSKDSNEM
                     IESVFGPGKAAFTIMLSSAATSVFDESFPDLNWGFVTGLEDKKAATFGAVDHLSLMSS
                     AKNKELAYKLIQHMLSVESMTEFHKAIPRAPITKGEPYQGDERFKEMVENDKNVYRPL
                     VVGPHGVEIYEYLWKELQTMISGDKTPKQALDDAAKYSNDLLAQ"
     gene            17907..18824
                     /locus_tag="KR294_000690"
     CDS             17907..18824
                     /locus_tag="KR294_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBH0238806.1"
                     /translation="MENLVREFEENSKRKKTKLNIKPYMYILPLGIILVAFYVIPIIM
                     SIYFSFTKYNIISPATFIGLENYKKLFTDETLKVSIINTIKFTVVVVPCQTILSLILA
                     VWITGKGNSKIASFAKGAIFIPVLSSMVLIGMVWRALLNGEGSIIYQVLGAFGIESSK
                     LLGDSKTALPTLMFISMWKNIGYFMVIYISAIMNLPKHCYEVAKVDGATKLQEFIKIT
                     VPLLKPTTIMVVFLGSIWSLQVFDLIYTVTGGGPGISTMSIVMHAFNLNFKNFNSGYA
                     MTVANVLFLLIAVVSILQNKLVRRDNSDF"
     gene            18840..19649
                     /locus_tag="KR294_000691"
     CDS             18840..19649
                     /locus_tag="KR294_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBH0238807.1"
                     /translation="MKTARRLLSDGLLLFIACASLVPFIYMLIISLKITYNSYSLDIS
                     FSTVTLQNYIDIFTKKGFAQYFFNTAIVSFSGVLLNLVFSTLAGYSFAKMDFKGSDKL
                     FLFMIMTLIIPSQVTMIPLYIIMKHLGWINSYLALIMPIPTAFGVFIMRQAILGVPKE
                     LLESAKIDGCSDFRILIQIVLPLIKPALITLAIFTFMGAWNEFMWPLIATTKDTMRTL
                     TVGLSTLKTFQITNYGQMMAGATITFLPPFIFYLILQSKFVEGVSLSGIKG"
     gene            19707..21455
                     /locus_tag="KR294_000692"
     CDS             19707..21455
                     /locus_tag="KR294_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4091 domain-containing protein"
                     /protein_id="HBH0238808.1"
                     /translation="MEISYVLKDCTFKHNKYSVVEAETWKDKDLDIVVAKGEKFAFQI
                     MLKATEEFNCTIDKSSAISWKGLGNRVRLALNMPNSLENNFSINILGYVQDDTKAFVN
                     DAILRDKDVLVEQYLPQTFWIEGQVPEDFEENNLDIGIDIFKSFGYEDEEKVCTIDVP
                     VKVRNVVLKPLDESKFFLDLWQHPSCLARMYKVELWSDIHFEIVDNYLKELASLGEKV
                     ATVIVSDYPWAGQSCYKVYKNPSNLYEYNMVSVSKGLDGKIKCNFESMDRYISIADKY
                     KMAKEIDLFGLLGNWCAGEFGNPVEGYKDPIRVRYFDEKDKVFKFINNTNDLKEYIGL
                     VLNHLIECGLWDRVRIIADEPNNPEVVKECIEFINSTVSTHQVKYKSATHDQNFLDRA
                     KDEIDDMSINLKLTIQNYKDIESLKKKINDKGGILTWFVCCFPEKPNSFLSSPFVENR
                     IIGWYTYYFGLDGFLRWDYNLWTEDPWKDSSYKFPIWKAGDMFFVYPGKDLKPVRSVR
                     MENLRFGIQDFELFTMLEKEKGREYIEVELMQELLNKKENAEIKGFGDIELGYSLDNW
                     GYDKVKKYVLELLDRV"
     gene            21717..22739
                     /locus_tag="KR294_000693"
     CDS             21717..22739
                     /locus_tag="KR294_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 5 protein"
                     /protein_id="HBH0238809.1"
                     /translation="MFGGINIKRIGIIIMFFLSISFIGFYLVIRDNSDTVKMQRGINI
                     GNALESPKDFPWDVKMSNKFFDDIKDAGFDTVRIPVRFSDYTSDSDNFKIDEEFFKKI
                     DKYVDYALDKDLIVVLDLHHFEEIMKEPRVHKEKFLKIWQQIANRYQKYDKKLVFELL
                     NEPKENLYSQLLNEYIEEAIKIIRKTNPKRTIIVGPYNFYQIDYLNELNIPKDSNIVV
                     SFHYYEPNDFAFQGNIYHKGFEHLSNITWEGTNEQMDYLKKRFDTVENWANKNKVKIF
                     LGEFGITKEAPEASRRAWIKAVREEAEKRNFSWAYWELASGFGIYNQIEGTWDRDILS
                     ALIEKR"
     gene            22744..25050
                     /locus_tag="KR294_000694"
     CDS             22744..25050
                     /locus_tag="KR294_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBH0238810.1"
                     /translation="MKKNSKKILITLTIITNVIYILWRIFYTVPKEEGKFALICAIIL
                     LFVEIMGMMEMFVHYYGMSNIEYPEKPIISEELYPHVDVFIATYNESVDLVRKTVNGC
                     IHMQYPDKKKVHIYICDDGNREEMCILAEKMGVNYITRTEREGAKAGNLNNAMQHTNS
                     PLIATFDADMIPMHDFLIATVPYFLKNEQAKKDGEKEEYEKVGFVQTPQSFYNPDLFQ
                     FNLHSEGRIPNEQDYFYRDIQLARNRTNSVIYGGSNTVISREALEEVDGFYTYSITED
                     FATGILIQSKGYRCYAIPEVHASGLSPTDLKSLIKQRERWARGCIQTGRRLNILFRRG
                     LGFWQKISYISSITYWYASIKRFVYIMAPILFSVFNVIVVKCTLLQVLVFWLPMYILS
                     SLSLKIFSQNIRNTRWTNIYETIMFQSLMPAVILETFAISKNKFSVTNKSKLEENRMY
                     KFLQGIPYFIYMVLSIIGILKMFVAIFKMSSMTYSVVLFWLIGNLFNLVMATLFISGR
                     QQLRKSERYIAEIDFKLKQNSYVLSSKTIDISENGFAFLLENPEYISPEEEFEVEFRE
                     KSGNEMYIANMKAKIVNVVEVNSKWKYAAYITHIEDSEIDNWMCIVHDRIPTLPMTIS
                     NQLGFFDDLQINVKKRIEKTRTLSRRSPRINMNFQMDIKNTGKLRIVNFNYQYVLLNF
                     ENKSIYPKEIALEINENIVLECDLCEGKIDERGILYKVNNIDSIMQNFFLRDEMMDWI
                     LQNKKILDSKPSEKKEKSIDEFEPMEYI"
     gene            25022..26137
                     /locus_tag="KR294_000695"
     CDS             25022..26137
                     /locus_tag="KR294_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0238811.1"
                     /translation="MSLNPWNIFRRDEMKTLKVFFCSTKYLILVFIFFINTTFISSAT
                     SDKILDLSFKKIETDLSSKITYEDTGVKIETDSSKSDKERYLYIYQNIKENWSMYNNF
                     YIEIQNKNKSSQRINLSIQSKNMLEFRLKEGSEVFLEGKNIIYSDKIKEGCIEVPGEF
                     EGKIYVNFNSLINEESNVVLDSNMLSNIVSWGITFIPSDEEHNIVIIKKISLLSEEKL
                     RFLNNIKIIGDEEVQIPVLGQSISQYEVLGLKSDSKIKYSLMGKQDNVSISQNGKLTL
                     SNKAKPGQIILQVNVDDKFKIGKKITLTESWSINKKDKDGVPYTLVSPEQSPTVQDMK
                     KINFMNNIITFVRILFVSLVIICFGIYLYWKKCSKTK"
     gene            26155..27573
                     /locus_tag="KR294_000696"
     CDS             26155..27573
                     /locus_tag="KR294_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBOAT family protein"
                     /protein_id="HBH0238812.1"
                     /translation="MLFSSLIFLFYFLPITLVLYYVFRFNRTIQNMILLAVSLFFYAW
                     GEPKFVVIMIVSIIMNYIFGLLVDRYRESKIKVKVFLVLMCAYNIGVLFIFKYLAFAL
                     RNISELISTELTIPNIILPIGISFFTFQGMSYVIDVYRRHGEVQKNPFYVGLYIAFFP
                     QLIAGPIVRYESVAEQILNRKETWNKFSIGTCRFITGLGKKVLISNNMAIVADYIYTM
                     NSQGEIAASLAWLGSIAYTLQIFFDFSAYSDMAIGLGLMFGFKFEENFNYPYISKSIS
                     EFWRRWHISLGMWFKSYIYFPLGGSRVANKDIMIRNMFIVWLFTGIWHGAEWTFVIWG
                     ILNFVFLIIERFIMFEKIENHNFIKHIYALLVVNFGWVLFRSPNLKEAYNYFKAMFGG
                     NGAIWSDYTYMFLKEYWVFFIFAFIFSVPIAKKINKFVVEQAKYSMIFNVFYPISAIL
                     LFFISVTYLVTGSYNPFIYFNF"
     gene            27588..28796
                     /locus_tag="KR294_000697"
     CDS             27588..28796
                     /locus_tag="KR294_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0238813.1"
                     /translation="MNRFFKVRLITAIMFLIILFAFSIFNVCYSGKDTIQEIKNSIAE
                     KSSLKDTISSIDNTVNDKVIYKNTFIETYGYLQKLMGKNEFSKFSVVKDTSGKMHYTY
                     FAKAPNPVGVIADRVRKFSDEMEKQNTKLVYLMTPDKYIKGVTKFPKGIPYSYSNETA
                     DNFLNQLKKYNVDYIDFRENILKSGIPKDDLFFKTDHHWKVETSFWAFGELVEQLNKK
                     YNMNLDENHYYRDKDNYNSIVYPKSFLGSMGRKTGILYGGIDDFTLIYPKFKTNYTYY
                     TDSKSQKFELKGRFEESLILSYPFNADLDLMDGQSDKYFTYLLGNRPLVKIKNIENPD
                     GLKVLFVKDSLIVPTAAFFSSVCSSIDMIDPRYYDGDILEYAKSHDYDFVFISVYPQN
                     LTKEFFPFCE"
     gene            complement(28870..30258)
                     /locus_tag="KR294_000698"
     CDS             complement(28870..30258)
                     /locus_tag="KR294_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:dicarboxylase symporter family
                     transporter"
                     /protein_id="HBH0238814.1"
                     /translation="MESSFLSQFLMITDFKTIFFIILLLGTFFIVRQFEKKKIKFSLR
                     TIYATVLGLILGIIIQAFAGFPNDTTQVTWLQEVSKWYSLFGSGFMDLLKMLVVPLVF
                     LSIIKVIINMKDNNLGTLTFKSLGMLLATTAIAAIVGIIVANIMKLGVGANMPTLVEN
                     QELKEINSLVDTLRGLLPSNPVMAMANGNIVATIIFATFIATSIKRLSKKHFETIKPF
                     IDFIEASYKIIVSVSMTVIKFMPYAVVALLANTITSQGISSIVSVLQFILALYISVAI
                     LFIIHLIFITLNGLNPITYIKNSTEALLLAFTSRSSLGTLPVTIESLVQNHGVDEGVS
                     SFTASLGANMGMNGCAGIYPALMAVTLANMAGVNMDMSFYVMLLIVITISSFGIAGLP
                     GTATMAVSVVISGVGLGSYFPLVGGILAIDPILDMGRTMINVNGAMVSSITVGKSLGK
                     IDKEVFSKKNIS"
     gene            30599..31933
                     /locus_tag="KR294_000699"
     CDS             30599..31933
                     /locus_tag="KR294_000699"
                     /EC_number="1.8.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-disulfide reductase"
                     /protein_id="HBH0238815.1"
                     /translation="MRVIIIGGVAAGMSAAAKLKRIKPEYEVVVYEKTEIVSFGACGL
                     PYFVGGFFNDADELLARTPEKLREAGIDLNIFREVVEVDSESKKIKVKNIKTDEIYED
                     YYDKLMIATGARSIMPPIKNIKLKNVSTLKSLYDGEYLKKLLSNEDNKRVTIIGAGFI
                     GLEAVEACKKLGKDVDVIQLEDRILPQVFDKEMTDVLEEEINRHNVNLHLDEMVVELC
                     GEDKVEKVITNKGEIDTDVVIIATGVRPNTEFLSNTNIKMLKNGAIVVDEYGRTSVED
                     IYSAGDCATIKNIVSNENVYVPLATGANKLGRIVGENLAGREVSYQGSLSSSCIKIMD
                     MEAASTGITEKQAKDLGINVKSKFISDYNQTHYYPGRNKIYVKLIYDADTKVILGGQV
                     AGFKDAVQRANVLAAAIFGKMTTNQLGMLDLCYAPPFARTWDVLNVAGNVSK"
     gene            complement(32075..32992)
                     /locus_tag="KR294_000700"
     CDS             complement(32075..32992)
                     /locus_tag="KR294_000700"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011969064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HBH0238816.1"
                     /translation="MIDLTLLGCGGNVPMPNRFLSSVFINYKGRKILIDCGEGTQVSM
                     KLKKCGFKDIDLICITHLHGDHIFGLLGLLSTIGNSGRTSDLTIVGPVGIVDCIRSMR
                     NLVEYVPYTLKIIENPQGNFSLDNKVLRNLEISTISLEHSIECLGYSFNFRRNPKFDI
                     DKATKNEVPKILWNKLQEGQNIVLDSKQYTPDMVLGELRKGVKISLTTDTRPIESIPD
                     FIKDSDLFICEAMYGDDLDISKAVRNKHMTFREAANLAKLGNVKQLLLTHFSPSLDIP
                     SMYLENATNVFENTILGEDRLSLRLNFDE"
     gene            33200..34084
                     /locus_tag="KR294_000701"
     CDS             33200..34084
                     /locus_tag="KR294_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4846 domain-containing protein"
                     /protein_id="HBH0238817.1"
                     /translation="MKVLKKITILSLITLTLVGCSNGEDKKVVEGSKKIQNSKKDEQP
                     IIVHKDANILKDRYEPPKGFKRVDVEKGSFESFLRNTKLKNYGEKVKYYDGRTKESKG
                     IYDSVFDVDIGNRDLHQCADAIMLMRAEYLYQNKLYDEISFDFVDGFKAKYSKWAQGY
                     RISVKDSGSSWYKATEYSTSYESFRKFMDIVFAYSGTLSLEKELEPVKVEDMKIGDVF
                     IVGGSPGHASIIMDMAENEKTGEKVFMIAQSYMPAQQTQLLINRKNPNLSPWYSLDFE
                     GDLTIPQWTFKRDQLKRF"
     gene            34297..36138
                     /locus_tag="KR294_000702"
     CDS             34297..36138
                     /locus_tag="KR294_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-nucleotidase C-terminal domain-containing
                     protein"
                     /protein_id="HBH0238818.1"
                     /translation="MKIRRYLILVIIILITTSQSFISYGLERFEEITIFHTNDIHGRY
                     AEGDDHIQIGNLATLKKETPNSILVDAGDCLHGLPIVNMDRGKSAIELIKCAGYDYIT
                     PGNHDFNYGKDRLFELSKSANLGENTLKFLSSNIFENGKKVFDSNDIKEIDGIKIGFF
                     GLSTQETKSKTGFKNVEGLEFKNPIESATEQVNELKGKGANVIVAICHIGTNSLSKPN
                     SIDIANEVQGIDLIIDGHSHTKFENGKQVGDTLIVSAGQYLENIGEIKLTLDTNDVEN
                     IKIENKSVRLIGKEEALKYKLDSAVSKKVDEIKEQQEKILDKVIGVTTNTLDGSYENV
                     RTKETNLGNLISDILLDKTKADISLFNGGNIRDTIEKGNITRRDIVDVFPFSNTIVTK
                     ELTGAQIKDVLEHGVKLYPEKSSAFLQVGGISYYFNPKQKEGEKITNIQKEGKPLDLN
                     KKYVVATNDYIASGGDEFPCFSKEPVLKEFGNLESAVIEYIEYKKEISKNVDGRIGIK
                     SKDELISKNHESDLILSENEKNINDNEENLSNNIKSSDSDKNKSLDKTSARESSNLGI
                     SKREAKEKSPKTGDLGFSNSIIIFIVSSTLICLLNFNQKELKDKKSK"
     gene            36443..37150
                     /locus_tag="KR294_000703"
     CDS             36443..37150
                     /locus_tag="KR294_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0238819.1"
                     /translation="MNNILLLEDDKSLNRGISFKLKKEGYNVFSAFGIEEAKNIFAKE
                     EICLIISDIGLPDGSGFDFCEEIRKKSDVYIIMLTALDEEVDIVTGYDLGADDYITKP
                     FSLMVLISKVNALMKRVNTVKNYTLLVCDDLFFYYIENKLIIRTDDKEEEIILSKTET
                     KLLKYLMENSMQTLTKEQLLESLWDSSGNFVDDNTIAVNIRRLRQKVEKNPSEPKYIK
                     TVRGVGYMWGERSIKKC"
     gene            37144..38454
                     /locus_tag="KR294_000704"
     CDS             37144..38454
                     /locus_tag="KR294_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH0238820.1"
                     /translation="MLKNMNLKDGLSVKDDYIMRRVIVYSVLSVLIVTLVFILFEYSR
                     LHKLYEHQIKNTQNIAGILIEKYPNDEIDIVNSIYNSDYSKVSTGEKAFKKFGYGLEN
                     KMSNDKNFSLYLKSFFKESFFIFLMMFIVVIGIIYYFIRYINKRLSKIYFIVDKMSQE
                     NYLKDTTESEETGYLVEYNEYFKEGIFSKINNCLYELNRSLKIKFIKLEKEKESVKSL
                     VTDISHQLKTPLASLKLYNTLLIEEELEEDEANEFLLTNKASINKLENLINSLVNISR
                     LEISMINIKKEDNDIKNTILNAVKSVTPKAKSKSITLNLNEFNSRIIPHDKKWTEESI
                     FNVLDNAVKYTQVNGEINISVEETANFFKIIIEDNGIGIEKNEFNNIFKRFYRGSADE
                     IESVEGSGVGLYLSRKILEEQGGNIIVSSKVGIGSKFSLFLTTM"
     gene            38571..39254
                     /locus_tag="KR294_000705"
     CDS             38571..39254
                     /locus_tag="KR294_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0238821.1"
                     /translation="MKILYTENLSKHYGKGESLVRALDNVDLEINEGEFVAIIGKSGS
                     GKSTLLHMIGGLDIPTSGKVYIDNKNIFTLKEEELAVFRRRKIGFIFQSYNLIPSLNV
                     WENVVLPIGLDGREVDESFIKELLKSLGLENKHDVLPNTLSGGQQQRVAIARALATRP
                     AIILADEPTGNLDSKTSDEVMSILKSMSKKYSQTLVMITHDDSIAQMADRVIFIEDGR
                     VSKVGDKND"
     gene            39247..41634
                     /locus_tag="KR294_000706"
     CDS             39247..41634
                     /locus_tag="KR294_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HBH0238822.1"
                     /translation="MINTTKIAKSNLKQNKSKSILIIITIILSTLMLSSIGIYIVDAG
                     AYQKENTIKYSGNYQGILANVDEKQADILSNHADVELTGEMNGVGVEKLEDDSNISLA
                     YMNEDALKLNSFEFIKGKLPSKENEIVLDSGALKALGYKNKDLGEKIKISYDDYKNDK
                     KIEKEFIISGILKTSEISEAGKYYYAIISESYMRNTRDMSQEDFNIYVKFNDKSNLSI
                     EQAKEKLDKIANDIGLDTINTAVNENYINALKPDMETIMGGVFVGLVIVLSSILVIYN
                     IFYISIVTKVQEFGKLRAIGATKKQIKNIVFKEGFILAGIAIPIGIILGYVLANIIIK
                     SFMDIDVKSSRLPVILSVVVISFISVVLSLLKPMKVASKVSIVDAVRYTGNKISNKSK
                     RKGYKNINLKRLSHANLERNKKRTYMTLASLILSGTIFITVSTALESFDAEKMAREHF
                     PYDIEVRLSGYEMNSDKNPKDNLNILQMDNPLSKDFFNQIKNMEGIKRIESARSVKIG
                     MEDYDVEFKYDLLQSINENDVKSLNKNIIDGKINLERLQTGDEIVITHVDTAKEMGVK
                     AGDKIRLTLYDGDKKIKKEFKVQAIAMGVPSFGIGKDFIDRTLKYDSTSSLGIYTEEG
                     KYQEIKDSIKKIAKNNGFLETDFIDSRIESNKATISFIKIMGYTLTGIIGVIGFMNLV
                     NTMITSIVTRKKELGMLQAIGLTNKQLVKMLNSEAIYYTSGMMIGSILFGGILGYIAV
                     IFLKKTGLSYATYSLPIVPILLMIVCILIAQFITTYLIGRSFNKESLIDRVRYSE"
     gene            41914..43056
                     /locus_tag="KR294_000707"
     CDS             41914..43056
                     /locus_tag="KR294_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--glyoxylate aminotransferase family
                     protein"
                     /protein_id="HBH0238823.1"
                     /translation="MNKKINYAPGPTETRENVRLARAEKTTNPDIDIDFVEFYKKTCE
                     KFGNIIGTKNDVYILSGEGILGLEAACASLTEKGDRVLVIDNGIYGEGFKDFVTMYGG
                     EYVLFSSEYTKSIDIDELKAFLDEDSNFKYATVVHCDTPTGVLNDVSKICPLLKKYGI
                     LTVVDSVAGMVGERLSVDESKIDIILGGSQKAISAPAGLTIVGISQDAKNCIKNRKTD
                     VIGFYCNLNIWEGYYEKKYFPYTMPISDIMGLDKALDNILEEGIENVLNRHEKIAYSV
                     RKSIEEYGLELFLEEGYSNTVTAIKIPESIGALELTDYMLKNYNTLVATSLNQYMDTI
                     LRIGHMGENANLNKIEHVLNVLDKSLSALGFKGNGNLLNLFNKYYF"
     gene            43075..43599
                     /locus_tag="KR294_000708"
     CDS             43075..43599
                     /locus_tag="KR294_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBH0238824.1"
                     /translation="MEVTAKQKFTTKDMVETSLLIALVFIATKFINIRLPISINGGLV
                     HLGTAMLFISAIVFGGKKGALSGAIGMSLFDLISGWTLWAPFTFIVRGVMGYLLGKIA
                     WANGNNGNNFLINVIGICVSSIWMLFGYYVTEVILYGNFIVPLTSIPGNLMQVLIGLI
                     IALPISKVLKKCIK"
     gene            43699..44517
                     /locus_tag="KR294_000709"
     CDS             43699..44517
                     /locus_tag="KR294_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBH0238825.1"
                     /translation="MLSVTRYSIKNVRLKPWVKFIWYFETKSNILLNNKLLPTDSIDI
                     ILNLSDVMEYKIENQDYTASNMHFNGIRDKHGFIIQHGNIRVIGISFYPFGLYPFLKI
                     PISEFNRQIVDLEAVSQLFAKKLEESLNPTQSVEKIVLYLEEVLLSILEEDLISNKYV
                     KLLNSFIYVNRYSNIKAFCDDTNINIKTLERICLKYTGYTPKILKRIYRFKMASNQLI
                     YNYKDDELFDFIYENEYYDQAHFIKEFKKFSGTSPIKFIGENKTIKENIKYSYL"
     gene            44595..44906
                     /locus_tag="KR294_000710"
     CDS             44595..44906
                     /locus_tag="KR294_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HBH0238826.1"
                     /translation="MKIITEIVEFNVEENLSKEEFIEIVNDLELKFHSIQSGFIDTEL
                     LYDEKSQKWIMIQHWESIEDLKSASSKMFKDSSTEKFRKALKNQTVKMNIIPQIKSWK
                     L"
     gene            complement(45033..47036)
                     /locus_tag="KR294_000711"
     CDS             complement(45033..47036)
                     /locus_tag="KR294_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha amylase C-terminal domain-containing
                     protein"
                     /protein_id="HBH0238827.1"
                     /translation="MKSQKRFKILDIDVYLQPFESDIKKRMKHYENMKSKTLKNYKDF
                     SSFANAHLYYGFHQTNDGFFYREWAPNADSLSLIGDFNNWNRKSHPLRKIGSGNWEIF
                     IPGQNSLPHKSEVKVQVTANGKTFDRIPLYIKRVIQKDFGGFNGQIWQPKTPFIWTDN
                     DFDLKNITYPLIYECHIGMSTESESIGTYNEFTEKILPKIKKAGYNTIQLMAIMEHPY
                     YASFGYQVSNFYAISSRFGTPEDLKNLINTAHSMGIAVLLDLVHSHAVKNTLEGINEF
                     DGSEHQFFHSGSKGNHPAWGTKLFNYGKPEVIHFLLSNIKFWLNEYHFDGFRFDGVTS
                     MLYHNHGLGVSFDSYEKYFSMNTDIEAITYLQFANELIKEIKPNSISIAEDMSGMPGM
                     CIPIKDGGIGFDYRLAMGVPDFWIKTISNLSDEDWDLGKMWYELTTRRPGEKNIGYCE
                     SHDQALVGDKTIIFWLADKEMYWNMEINSNNHVINRAISLIKLIKLITFSLAGEGYLN
                     FMGNEFGHPEWIDFPREGNNWSYKYARRQWSLSEDNNLKYKQLLNFDKSMLELTKYSD
                     IFIQNSHELIHMDNDKKILVYSKGKYLFIFNFHPNLIQSVDISKFQNTNYKTILNTDM
                     VEFGGNTKKENLRDYDVYFSSTPPSSKMPIASRTAIVLLDSSI"
     gene            complement(47189..47827)
                     /gene="recX"
                     /locus_tag="KR294_000712"
     CDS             complement(47189..47827)
                     /gene="recX"
                     /locus_tag="KR294_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HBH0238828.1"
                     /translation="MGIITKIEQQKRNDDRVNIYVDDKFFIAIFKELVYTFNLKKGNE
                     INEEELKPILDDEMYIKAKNKALNILSHADQSEKKLKEKLSSEFDENIIERVIDFLKS
                     YNLVNDSVLAQKIVNTNVNLNKCGKNRIKQNLYNKGINRSTINEAVSELDKDTEFENA
                     MYLAKKRYERVKKEDKKKIYQKISQHLSYKGFDYDIIKRVLNKLLNFDEYDI"
     gene            48103..48792
                     /locus_tag="KR294_000713"
     CDS             48103..48792
                     /locus_tag="KR294_000713"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HBH0238829.1"
                     /translation="MRSENLVKMAELKNTEKLEKFNRHKGKIKIGILGGTFDPIHYAH
                     LATAEFIRDKYDIDKIIFIPSGNPPHKLCITTDKYDRYNMTLLATESNEDFLVSKVEI
                     ERKKRTYTIDTLKYLKKKYKNADIYFITGADAICSVEEWKDVKKNFELATFIAATRPG
                     ISLLRSQETIEKLTKKYNADIITVYVPSLDISSTYIREQLNEGKSIRYLVPENVENYL
                     YENKLYQYGDD"
     gene            48793..49365
                     /gene="yqeK"
                     /locus_tag="KR294_000714"
     CDS             48793..49365
                     /gene="yqeK"
                     /locus_tag="KR294_000714"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HBH0238830.1"
                     /translation="MNLENINQRLNQMLPVGRLSHSKNVAKCAEKLCEIYGCDKEKAY
                     LAGMIHDCAKYLSDKEIEDYVNKYEIYLDPIEDGNRSLSHSVIGAYICEYEFEVEDED
                     IINAIKYHTTGREDMSLLEKIIYIADLIEEGRKFPVVDTLRELAYGGKLDEALLTSFN
                     NTLMFVINKKEEIHPRTVMARNYLIKEKLL"
     gene            49482..49832
                     /gene="rsfS"
                     /locus_tag="KR294_000715"
     CDS             49482..49832
                     /gene="rsfS"
                     /locus_tag="KR294_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HBH0238831.1"
                     /translation="MTVEQMTKIAYDAIEDKLGQDTVIINIGKVSSLCDYFIITTASS
                     QRQVKAIADNVEDELAKLGLEPRGKEGQGTQTWVLLDYGDIMVHVFNEENRGFYNLEK
                     LWKDAPYIDIDTLA"
     gene            50186..52606
                     /locus_tag="KR294_000716"
     CDS             50186..52606
                     /locus_tag="KR294_000716"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HBH0238832.1"
                     /translation="MSVYNFKEVESKWQKIWKDNNQYKMDTAQTEKPNYYTLEMFPYP
                     SGKIHMGHVRNYSIGDVVARFKKMEGYNVLHPMGWDSFGLPAENAAIKHGIHPHKWTM
                     ENIEEMKEQLNLLGISYDWDKEVATSTPEYYRFTQEIFLKFLEHGLAYKKKSYVNWCP
                     SCETVLANEQVVQGACERCKATVLKKDLEQWYFKTTEFAEELLNDLDTLDGWPEKVKT
                     MQKNWIGKSTGADLVFDIDGTDKSMTVFTTRPDTTYGVTYMVLAPEHELVKELVAGTE
                     YEADVEAFVQKMHTMTEIERTAADVEKEGMFIGRYVINPLNGKKVPLWIANYVLVEYG
                     TGAIMAVPAHDERDRDFAEKYNLDIIDVITEDNKMINSEEFNGLDASEGFEGIIDKLE
                     KEGRGKRTINYRLRDWLVSRQRYWGCPIPVVYCDECGIVPVKKEDLPVLLPTDVEFTG
                     KGESPLTTSKQFMSTTCPHCGKPARREVDTMDTFVDSSWYFLRYVDSNNENEPFSKEL
                     VNRWHPVDQYIGGVEHAIMHLLYARWFVKAFKSMGMVDFNEPFKNLLTQGMVLMDGSK
                     MSKSKGNTVSPMDIIDEYGADTARLFVLFAAPPERDLDWSEQGVDGCFRFLNRVYRLV
                     DELADVVKKDVEFGELNSQDKDMRYTIHSTLKKVTADLSEKFGFNTAISALMELINDM
                     YKYKELDNINEAVIKEGVQTIVTIIAPFAPHLGEELWTMIGKEGSVFDIDWPKYDEKA
                     LVKDEIEVVVQVNGKVRGKLTVNSNISKDEMEKVALEDEKIKGLVEGKTIVKVVAVPK
                     KLVNIVVK"
     gene            53442..54110
                     /locus_tag="KR294_000717"
     CDS             53442..54110
                     /locus_tag="KR294_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBH0238833.1"
                     /translation="METVTNNQSGVEIQLSLFEAIKDLLLINPIFLLGIILIGIFLVV
                     IFKKNSDIPKVKTSILSLAMYYYLCLTLSHIVGIPTFGEYIRLSQLGETFFNPNINLI
                     PFSDGFSLSFILNILLFVPLGFLCPLISKTFERLRNTFLIGFGLSLFIETIQLFTLHR
                     ATDIDDLLTNVIGTIIGYFCFKLIAKLRIVKLHSDDDSMEQDYTVCIPIAIIIVALIL
                     GFFS"
     gene            complement(54428..54700)
                     /locus_tag="KR294_000718"
     CDS             complement(54428..54700)
                     /locus_tag="KR294_000718"
                     /inference="COORDINATES: protein motif:HMM:NF012798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBH0238834.1"
                     /translation="MSKHQFKSVSTFFTKKNVSQFYKKNNLKKIRIHDLRYTSATLLL
                     LGGTNMKVVSERLGHTDIKITMNRYSHVLKEMDKEASDNLSELLFK"
     gene            complement(54931..55352)
                     /locus_tag="KR294_000719"
                     /pseudo
     CDS             complement(54931..55352)
                     /locus_tag="KR294_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431042.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(55371..55469)
                     /locus_tag="KR294_000720"
                     /pseudo
     CDS             complement(55371..55469)
                     /locus_tag="KR294_000720"
                     /inference="COORDINATES: protein motif:HMM:NF026008.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Arm DNA-binding domain-containing protein"
     gene            55752..57122
                     /locus_tag="KR294_000721"
     CDS             55752..57122
                     /locus_tag="KR294_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp29"
                     /protein_id="HBH0238835.1"
                     /translation="MKLKKLLSLGLAVSMFAAGPISANALDTIYTIQGKDKYETAALI
                     ADEQNYTTAILINADSTMADGLSASGLAGATNAPIFLTKKNNIPNATLKRVEKAKKVY
                     IIGGESSIDKATETLLKDKGIEAKRLQGSDRIKTSYNVAKEINSINKVNKVILTNAFK
                     GEPDAMSAAPVAVRDKAAIVLTDGKSVPFNTTGVESYVIGGTSSMSDKLVNDTNSTRL
                     GGVDRYDTNKKIVNKFYNGAKEFYIASGTDLVYALVASPMAKNNPIVLVDIGSNKDIL
                     KNAAKVTGIGNLSDKIMLECENTINNISLPSSNKNIICGLKIDFDSKHIIWQDKGSYL
                     ECYDDNLEYYTEKYKDPTVPINIENTSTQNLDVTKLKVYGEANSTLYMGQYAKIKMDF
                     NSFGVLKPGEKCTIYLDIISLDPSRSMTLTFSYVGDKENYKYEQGLASRILFYNPDGE
                     DFFEYK"
     gene            57481..57639
                     /locus_tag="KR294_000722"
     CDS             57481..57639
                     /locus_tag="KR294_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0238836.1"
                     /translation="MDNFLQGILASLSASLIVYIASKLFRKRKKPLKAATKSGWEFDL
                     KIRFHKTK"
     repeat_region   57925..58282
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=57925..57953
                     /rpt_unit_seq="gttttatattaactatatggaatgtaaat"
     regulatory      complement(58424..58521)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            58747..59130
                     /locus_tag="KR294_000723"
                     /pseudo
     CDS             58747..59130
                     /locus_tag="KR294_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431032.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
     gene            complement(59319..60314)
                     /locus_tag="KR294_000724"
     CDS             complement(59319..60314)
                     /locus_tag="KR294_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HBH0238837.1"
                     /translation="MSIKKKVAIVFTGGTISMTVDDKVGAAIPTLSGEQILSMVTNID
                     KVADVEVFNFDEIPGPHITPYRMMELKNYVNDLLARKDITGVVITHGTDSLEETAYFL
                     DLTIDNIKPVIVTGAMRSSSELGYDGSSNLSASVCTAVSKDAMGKGVLVVLNNEVLLA
                     SEATKTNTLSLNTFKSLTSGPLGIIDCNELVLTRDIVNRTIIDTDKVESKVALFKAYV
                     GENADFIRFAVDSGYKGIVIEAMGRGNIPPQMLSGVEYAREKGLPVVIVSRCHSGRVF
                     DSYGYFGSGRDLKNLGCIFGGDLPGQKARIKLILALGKTDNLDEIKDFFEKGIYC"
     gene            complement(60435..62063)
                     /gene="aspD"
                     /locus_tag="KR294_000725"
     CDS             complement(60435..62063)
                     /gene="aspD"
                     /locus_tag="KR294_000725"
                     /EC_number="4.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate 4-decarboxylase"
                     /protein_id="HBH0238838.1"
                     /translation="MKNHTYKEIKNIYGKISPFEFKDKLIDIAKYTAKENNRELLDAG
                     RGNPNWTCSTAREAFFTFGHFAITETRSNWDLGHLAGMPQKKGIKERFFKFINENIDM
                     PGAYLARDIINFGINELGFDGDEFVHELADGIIGDNYPLPDRMLPHMEKIVHDYLVQE
                     MKYDISGKYGDVEIFAVEGATAAMCYIFDSLMANELLKKGDTIALMTPIFTPYLEIPN
                     LPRYDFKVVNINANEVDEKGAHTWQYTKKELEKLRDKSIKALFVVNPNNPASIAMDET
                     SCNNLIDVIENYNKDLMIISDDVYGTFVEDFSSLMSKLPYNTVGVYSYSKYFGVTGWR
                     LGTFALHKKNVFDKKINDLTGELKKSVDKRYSDMSLNPSSLSFMERVVADSRLVALNH
                     TAGLSTPQQVQMAFFSAFALIDKVDAYKKLNMSICHRRQKLLFEALELPINENKNNAA
                     YYTQFDIEEWAKLNYGEDLFKFISKTASPVDVLYKLANDYSVVLLSGNGFYGPEWSIR
                     ISLANLYDEAYTKIGKAIREILNGYIVEWQKIKK"
BASE COUNT        24028 a         6995 c        10458 g        20582 t
ORIGIN      
        1 gatactaaaa ttatagagta tgttgaagaa attttagaag taatcaacaa tcaatatact
       61 tttgacctta gaaatgatag tgtattattt gatgatttag tactgcactt taaatcaatt
      121 ctcaattcta aatcttataa tttaaataag gtgaatcccc ttataaatac aataaagagt
      181 aattatcctt tagcatttga aataacttta aatgctatag aaaaagtttt taaaaatagt
      241 atttactctt taacagaaga tgaaattgga tatgtatccc tgcatatagg tgctggaata
      301 gagagatttt ttcaaagtaa tattaagtgt aaaaacgtag tattagtatg tggttcaggg
      361 tatggttcaa gtaggttatt agaggttcaa ttaaacaaag tttttcatga taaaataaat
      421 atacttcaat gtctatcatt taatcaattt ttagctagtg aattgtcaga tgtagatata
      481 ataatatcga caattccttt aaatcatgat agtattccta ttgtattagt ggatttaaaa
      541 ctattaaaaa aagatataga gaatatatct aagtcaatca ctaataattc ccatatttat
      601 agtaatcttt tggacaattt ctttgataaa aatttattta ttgttaatcc taaaatcaaa
      661 gataaagatg agcttataaa gttgatgtgc aacaaattaa ctcaaagtga aattgtattt
      721 ccatcatttg ctgaatctgt attttacaga gaaagtttat cttctaccaa tatagatgat
      781 tttttagcta tacctcatcc tatggaatta agctctataa gaactaagat ttgtatttcc
      841 atattggatg aaccaatata ttggagtgaa gattctactg ttaaattaat catgatgttg
      901 gctataaata aagatgatta tataaaaata aactccattt atgatatcct tttaaagata
      961 attcatgaca atgatattag agatagtata tctaattgta atgattttga taattttctt
     1021 tccataatca agtctatagt atagattttt atattacata agttttaaaa actttaataa
     1081 aatatttttt gtttttagca taaatagtat aagtaagttt tgtataattt gttattattt
     1141 tgtattgatt ataattatta tacaataaag attctgtctc aaaatagaga gagaaacctg
     1201 tttttcattg ataaaatgat aaaaatatat ctgatttcat acaaaaaaga gtgtctcatg
     1261 aactaaaaag ttcattttga gacaccacct ttattatttt atattattta tctcttgtat
     1321 atattactat agcatccctt aaaaacttag ctaatccagg ttgttctcta tcataatatg
     1381 atgtaaaacg ttcatcatat acatacatct gtgctagaga ggaatgagct tctttagagt
     1441 atgtgttcca agtgtaactc aaccatttat gatgtaattt tgcaacttcc tgagccagtt
     1501 cactagaggc atcaccagtt ttaaaagctt ttttaagttt actaattatt tcgatattta
     1561 ggttttgcca attttcataa tcttgcttag acatattttt aagtttttta tttgatgtat
     1621 ctataatatc tttaccatat ttctctctaa tttcagttcc ataatttttt tcattttcat
     1681 caatcatctt ttctttaaaa ccttcaaatt tttctatatc tgtcatagtg tattttccct
     1741 ccttcagagc tatagtttta gttacatttt ctattagtaa atcaatttgc tttcttttgg
     1801 ctagtaattt attatggtgt tcttttaacg cacttaaact atcgaagttt ggtgaattta
     1861 taatgttttt tatattttct aagttaattc ctaattctct ataaaaaagt atttgttgaa
     1921 gtttattaac ttcattttga ccatatatac gataacctga agaatttatt ttaagtggtt
     1981 taagaagacc tatttcatca taatatctaa gtgttctagt acttatacca gctagtttac
     2041 ttaatttttg aactgtatat tccataagta gtacctccta taaattaaat atacactttt
     2101 acgcaacgta aatgtcaata cattaaaata taaaaattta tatcttttaa taaaaatata
     2161 aaaaaatatc tttactggat attttacaca caactgtcaa tactcactaa tgaaaattaa
     2221 aaaataaaat ttatagacta tctttactaa aaaatagagg gtctatagtc taggaggaac
     2281 tgtatgaatt taaaaagaag caatgaaaaa cgagaagagt acagaagaat gtattcagat
     2341 aaagaaagtt ttttaagttt gattcaaaat tttacaagtg tctcaatagc aaaagaatta
     2401 actcttaaaa atatagagtt agaaacatct tttatatgtg aatataaagg aaaagaagtt
     2461 gatataattt ataaggtatt ttctaaaagt ggcaaagtat cacattatat agtgttagaa
     2521 tttcaaacag aaatggatac tgaaattgtc ccaagattga aatcgtatag agaacaaatt
     2581 tggaaaagtt ttattatgaa aaaaagcctt gaagaaatag aagataaaaa ttttaaactt
     2641 cctaaagtta taccagttgt tttatatagt ggacctgaaa ggttaagtag aaaaaaagga
     2701 attttggata ttgtagaatc tatatcggag ttcagtaata attctagtat gaaaaattaa
     2761 aattacataa tgtgtttatt ggtctaaaat ggaaaactgt cgcataaact tgaatatgaa
     2821 aatatttata gatacaggtt ctatgtggag gtgttccatg agaaataaca agtctaaggt
     2881 attgctagga atactttgtc tagcaacagg aatggctgta attctgtcaa tgttgcttcc
     2941 tggctggatt tggtcagcac ttaccgcatt aatacttatt ggatgtggag cattattatt
     3001 tttttgttaa aatagtttta actataaagt gtggggtgag tattgatgaa agtagtaaca
     3061 ataaaattac caaaatggat ttcaagtata atcctaaaat ttatgagaaa gagtaaaaat
     3121 gattaaatta aaaagcctac ttacggaagt aggcttttaa acgtggttac taagctcttt
     3181 caattttacc agaacgtaaa catctagtac aaacttttac tctcttagga gctccatcta
     3241 taatcgctct tacgcttctt aagttagctg accatgttct tttattatgt ttatttgagt
     3301 gtgatacttg gtttccagaa accttacctt taccacatac gctacatact tttgccatct
     3361 acgcacacct ccttaaaatg ataactattt aaagactaaa aacatattta tattatcata
     3421 aataacaaaa atttgcaata gaaatatata tttgccttac acatattgaa gaatttctta
     3481 ttatcatata aaattatata tataatttta tataaagtaa atatatttgg aaaataatta
     3541 ttatttttct ttgaatatat atactataga agaaatttta tccaaaaact tttctaggtt
     3601 taaattatac catatttata gtatgatatg attataattt tatataataa ataagtaaaa
     3661 atagtaaaaa ataaattaag aaatgttttt aataaaaata agcttaaggg ggtcaaccat
     3721 gagtgcaaag gtaacgaatc aatatggaaa tatagaaata gataatcaag taatagctca
     3781 agtcgtatat agagctgcaa tggaaagtta tggcttagta ggtttagcat ataagtctaa
     3841 aggaatagta gagctattaa aaggcgagaa cgcaactaaa ggtgtaagag ttgaggaagt
     3901 agaagaagat gccatagcaa tcgaacttta tgttataata caatatggta caaatatatc
     3961 tactgttgcc aataatataa tagatagagt aaaatatgta gttgaaaaaa tgactggcgt
     4021 aagagttact agaattgata ttaatgtaca aggaataaga gttaagtaat ttcataggag
     4081 gaaacaaatg attcaatata tagatggtaa aaggttaagg gagatgttta tttcaggtgc
     4141 aaacaatctc caaaacaata aagagttagt tgacaagtta aatgtattcc ctgtaccaga
     4201 tggagataca ggaactaata tgtcattaac aatatcttat gccttaaaag aattagcaaa
     4261 agttgaaaat gataatatat cagatatcgg aaaagcatta tctaaaggtt ctttaatggg
     4321 agctagagga aactcaggag ttatactttc acaaataatc agaggtatag ctaaatctat
     4381 agaaggaaaa agtaaattat caacagaaga tttagcaaaa gcttttaaaa atggttcaga
     4441 cacagcatat aaagctgtaa taaaaccaat tgaaggaact atacttactg tagttagaga
     4501 aagtggagag tttgcaataa aaactgcgaa aaaagagaaa gatgtagtaa agtttttaag
     4561 tatgcttgtg aaggaatcaa attcttcatt agaaagaact ccagaccttc taaagaatct
     4621 aaaagaagct ggtgtggttg actctggtgg aaagggtctt gtacttatat atgaaggaat
     4681 gttagcttct ataaaaggcg ataacataga aataaaaaat gttgacctag atactaatat
     4741 ttcaacaagt atggattttg caaagagtac tactagcaca gatgatataa aatattgcta
     4801 ttgtacagaa tttattttag aaagttctaa ggtagaagat actaaaataa gagacataat
     4861 gatggcttat ggtgatagcc tagcagtagt tggagatgat ggagtcataa aggtacatgt
     4921 acacactaat gacccaggaa atgtacttca agaagctcta aagtacggtc aattattaac
     4981 tataaaaata gaaaatatga agttacaaca tgaaaataca ttactggatg tagaagaaaa
     5041 gaaagaaaat gatagtgaac ctttagaaga agaaaaagag tttgggttta tagctacttc
     5101 tatgggtgaa ggtttggcaa atatatttaa agatttcgga gttgaccata taatagaagg
     5161 tggtcaaact atgaatccaa gtactgaaga ttttatgaat gctataaagc atataaatgc
     5221 taaaaatata tttattttcc caaataacag caatataata atggctgcta atcaggcaaa
     5281 agaattgagt gataaaaata taatagttat acctacaaaa aatacgcctc aaggatttgc
     5341 tgcattagta acttttaatg gagaattaag cgaagatgaa aataaagaag ctatgatgaa
     5401 tgctttaaac tcagttaaat caggtcaagt aacttttgct gttagggata cagtgatgaa
     5461 cgaaattgat gttaaagaag gtaatataat tggaattgca gaagggaatt tattatcagc
     5521 aggagattat gtggatgaag taacatcaaa ccttattgaa aagttggttg atgaagatac
     5581 tgctataata acattattct ttggtgaaga tgttacagaa tctcaagcaa atgaactacg
     5641 tacttcttta gaagaaaagt ttgaagatgt agatgtagag ttatattatg gaggacaacc
     5701 tctttattat tacttaattt cagttgaata atgattataa gaacctgtat gaccaagtag
     5761 cttttataaa attggttgta caggattttt gtgtagtagg tgatatattt gttggattta
     5821 tataaagatg ttcaatatgt taagggaata ggacctaaaa aagcagataa attaaataaa
     5881 ctgggtatat ttacactaaa agacctattg tattattttc caagacaatt tgaagataga
     5941 aataatctaa agaaaatagc acaattagaa gatggtgaga aagttacgat aaaagcagta
     6001 atatcaagta taaatacatt tagcccaaaa gaaggtatga ctttaacaaa gattgatgta
     6061 aaagatgaga caggctcggc taaattagtg ttttttaata agagttatat aaaaaatact
     6121 tttcgtccag gagattcaat attagttttt gggaaggtta agaaaaaatt taataactta
     6181 gaacttacat catgtgaatt agaatatctt actaattcac ctaagaatac atgtagattt
     6241 atgcctgtgt accagcttac atacggtgtt acaaataaag aaattatgag tataattaga
     6301 acagtacttg aagataaaga attaattata caagaatata tgccacaaag aattatagaa
     6361 aaatataggc tatgtagtat agattttgca gttagaaaca tacattcacc aagtagtaag
     6421 gaatcattaa aaatagcttt atatagaatt gtatttgaag aattacttat actacaacta
     6481 gggttgtttg tatttaaaag tggcagaaat aaagaagatg gaataaagtt tgaaacaagt
     6541 aaagacttaa aaaaaataat aagtgcttta ccatttaaac tgactaaagc tcaaaacagg
     6601 gcattagatg aaattataca agatatgaat ttagagaaaa taatgaatag attggtacaa
     6661 ggtgatgtag ggagtggtaa aacagtagta gctctcttag cacttgcaaa ttgtgtttta
     6721 aatggttatc agggcgcttt gatggcacct acagagatat tagcagggca acattatatt
     6781 tcacttactg agtctctaaa agattttgga ataaatgtag gtctattaat aggtagtctt
     6841 acaaaaaaac aaaaggatac agtattggaa caaataaaga ataatgagat tgatatatta
     6901 ataggtacac atgcactaat tgaagataag gttgaattta ataatattgg tttagttata
     6961 acagatgaac aacatagatt tggtgttatg caaaggagca aactttcatt gaaaggagca
     7021 aatcctgata tattagtaat gacagcaaca ccaataccaa gaactttagc acttatactc
     7081 tatggagatt tagatatttc tattatagat gaacttcctc caggaagaca gccaatagaa
     7141 acaattgcta ttgaaaaaag taagcgagat agagcatata ataaccttgt aagaagagag
     7201 gttgaatcag gaagacaagt gtacattgta tgtcccttgg tagaagaaag tgaagccata
     7261 gaagccaaat cagcagttga acttgttgag gagttaagag cggaatattt tcacgactta
     7321 aggcttgggt tgcttcatgg taaaatgaag tcaagtgaaa aagatgaagt aatgagactt
     7381 tttaaagata aagaaataga tattttagtt tcaacaacag taatagaagt tggtgtcaat
     7441 gtgccaaatg caacattaat gataatagaa aatgcagaaa gatttggact tgcacaatta
     7501 catcagctta gagggcgagt tggaagaggt agtcataaat cgtattgtgt actaatttat
     7561 gattctaaaa cagatgtatg tagacaaaga atggctataa tggaagagac caatgatggt
     7621 tttaagattt cagagaagga tttagaaata agaggacctg gggaattttt tgggacaagg
     7681 cagcatggtc ttccagaact taaggtagca aacttattta agcatataaa aatactgaag
     7741 ttagcacagc aagaagctcg atatatattg ggtgaagata ataatctaca attaaaagaa
     7801 aacatggcac tcaaaaaaga aattatagat aaatttaaag atacattgaa agaaatttca
     7861 ttaaattaat tttaaattgt gttaaaatat tactaatgta ataatgtgct gaagggagat
     7921 tgtcatattg agagtaattt caggaaaagc gagaggatta aaactaaata ctccaaaaaa
     7981 tgaagatgta aggccaacta cagatagagt aaaagagtct ctatttaata tgataaattc
     8041 atatataatg gaaagtgaag ttctggattt atttgctggg actggttctt taggaataga
     8101 gtgcttatct aggggtgcca agtcatgtac ttttgtagat atcagtaagg aaagcataga
     8161 tattgttaag tccaatataa aaaaggcaag agttgaaagt gaaagtatta ttttaaacct
     8221 tgattttaag actgcaatag ataaacttaa attacaaaat agtaaatttg acataatttt
     8281 tatggaccct ccgtattata aaaatatgtt tatagaagct attgaaaaaa ttgataattc
     8341 taatctattg aacgaagatg gaataatagt tgtagaacat gatacgaatg atttatttcc
     8401 agataagata tgtaaattgg agaaaactag agataagaaa tatggaaata ctacattaac
     8461 tttttataag atggaggcat aatatggaaa ataaacctag aaaagctata tttgcaggaa
     8521 gttttgaccc aattactaat ggacatttag atattatttg cagggcttcg aagttatttg
     8581 acgaattaca aataggagta ttaaataatc ctaataaaaa gggtctattt agctttgatg
     8641 aaagagtaaa acttatagaa aaaagtacaa gccatttaaa taatataaaa gttgtgactt
     8701 ttgatggttt attaataaat tactgtcagg aaaatgggat tggagcatta gttagaggtg
     8761 tgagaagtgg tgctgatgtt gattatgaac ttcagatggc gcatatgaat agagagctta
     8821 atccagatat agagactata attttaccaa gttgtacaaa atattcattt ataagttcat
     8881 ctttaataaa agaggttttg ctctttgatg ctgatataaa aaatttggtt ccaaagattg
     8941 ttttggaaga attaaagaaa aaaactagtg ggggtaattg atatatgaag atagatttag
     9001 aaatgattga actatttgag cagttagagg agatatttag aagtgcttct acaatccctt
     9061 tctcacataa atgcacagtg gataaagatg aggttttagc aataattaat gatataagaa
     9121 ctttaatacc agaagaagta acacaggcag tatggattaa taaagaaaga aataaaataa
     9181 taagtcaagc taagcaagat gctacaaata tagttgaaca agcgaaaaaa gaagctgaga
     9241 gaatacaaca agaatatcaa gataatatag aggaattaaa gaaaaattct gaagatgtag
     9301 taaaggcata tgtagaatcc agtgaacctg ttgttcaagc agaccaaaga gcaaaagata
     9361 tagttgatag agctgagaga atagccaatg agataagaat tgggtcaatt gaatatgcag
     9421 aggatgtgct ttctagtgtt gagtataatt taagagaaat attagaagaa gtaaaaagag
     9481 ataaagctga acttagacct aaaaaataaa ttttaaataa ataaaaatgg agctatcaca
     9541 caaaaaattc caatttatgt gtgatagctc tcttttaata tagcaatttt ttgttatata
     9601 attgtgcttt ttagattact tatatcttat tttgatatta taatgtagtt taatctttta
     9661 tttgttgaaa tcaacttatt tatttgtata aataatatag gttattttca aattttttta
     9721 ataattttac cactgtcttc ttttagatta gagttagact gtgcaaaatt ataaaataat
     9781 actaaatcat gtgcaattat ttggtatggc actacatgta gaaaatatag ataataaaat
     9841 taaggaggta gtatgaagga aagggctaaa aaaatattag attttattat taaaaataac
     9901 aatgtaacat cacaagaact acaagaaaag tttaatgttt caaagagaac tatttattac
     9961 gatattctag ctataaatga acaactagga aaaagtggta atataaaaaa tgtaaaacac
    10021 aaatttatat ttgaaggtaa tttatgtgat gcaaggaaaa taatttcaac tgaagaagat
    10081 aaatttttag atagtgatta cagaaaaact tttatattaa acaagatatt acttggcgaa
    10141 aaaatatcaa tagaaaaact aacaaatgaa atgttacttt caaaaaacac agtagtacaa
    10201 acaataactg atgtaaaaaa ataccttcaa acaatggggt taagattaga gtataaggga
    10261 aagtacaaaa ttataggtga tgaatacgtt attagagagc tgtttctgat aattgttcaa
    10321 gaaaatgtac tggaaattaa ttctataagt gaggaagtaa gtagtttcga tacaaaagga
    10381 catataaaac ttactgatta ttctttatta aatctaacta agtttgtgga atttctaaat
    10441 aaaaggataa gagatgggaa aacattatac tcatataaat atctaaatga agctaaaaaa
    10501 attagttact ttagtaattg taaagaactt ttatgtgaag aagctaatga aaatgaacaa
    10561 gcctatatat gcacttacat aagttcactt cccagcttaa atagtgaagt taaggaagat
    10621 gttgttgaag aatatgtaga taaacttata gataagtttg aagtaaatac agcaataaaa
    10681 ttagaaagta agcatgagtt taagaaaaat attttaaggc acctccactc ttcttacaac
    10741 agaatacgat ttaagtttcc tattagaaat ccaatgttag atgagactaa gtataaacat
    10801 gagtcacttt ataaaattat aaaatcaatt atagagaatg aagaagagtt tcctgtattt
    10861 gaggggataa gagaagaaga aataggattt atagcagcgt attttggagg atatttaaga
    10921 gggtctaggg ataatggtct aagaagaaat aaagtcttac tagtttgtcc taatggtctt
    10981 atggtatcaa agagtttgga aatacaacta tataaataca taccaaccat agaaatagta
    11041 ggtatagtat ccattaagca actaaaagaa gtaaatgtat actacgatta cataattaca
    11101 actatagata tacaaaatgt aaacaacgta attgttgtaa atcctctttt aacatcatca
    11161 gatgttcaat tacttatgaa caaactaata agtgtaaaag aaaacgagaa gtatttcaat
    11221 cttgaattaa taatacaagc tataagaaaa aatggagtta tcaataatga agaagcacta
    11281 aaagctgatt tattaaacat aatacacaag atagatgaag gagagatgta tcaaccaatg
    11341 ttaaaggaat taattaatgc agaaagggtc aatataataa aaaatgttag agattggaaa
    11401 gaagcaataa aaatagcctc aaagccattg ttagaagata actctataga agagttatat
    11461 atagaaaata tgataaagtc agttgagaaa tatggaccat atattgtttt agctgataga
    11521 tttgctctac cacatgcaag ttctaaagaa ggagtaaaca agcttgctat gtctttacta
    11581 atagtagaag atgaagttga tttattagga aaaccagtaa atatatttat ggtattagct
    11641 gctgtagata acactactca cattagagca ttagcatcac tatcagagat gatgtacgag
    11701 gaagaaaatg taaaactaat aattaatggt gataaaagtt caataataga acttataaat
    11761 aagcaaaatt agggggaatg aaaaatgaag atattagcag tatgtggttt tggtgtaggt
    11821 tcatcaatgg tattaaaaat gacaatccaa aaggctctaa agcagttagg tatagaatgt
    11881 gaagtagaaa atacagatat aaattcagct agaggtgctg attgtgactg tatattcaca
    11941 agtcaagaat tgttaaatga attaaaagga acttgtaatg tagatgtata tccagttaaa
    12001 aagtacatgg atttagcaga agtcacagaa gttgttcaaa cttttttaag tgataaaaat
    12061 gataagaaat agtataagtt ttaaaaagta aatttaagtt aatcagaata aaataaaaac
    12121 ttactaagtt caaaaatagt aagaaagaga ggagggattt agtggtagaa aacttaaaca
    12181 gttgacctat cactaaaaaa tataatgctt gattaaaaaa tagctacgca cactcgtgac
    12241 cttagtcatg agttagtagc taaaatagtc agcatatagg gaaacctata tgtagagata
    12301 ggatagaaat actacttgaa ttgctggaaa cccctaaagc taaccaaact aaaacataag
    12361 gatgaaataa acctaagtgt gaaagttacg aaagtagaaa aaattggtta gatggtataa
    12421 ggttaaaccc taagtacttt aaaatgggca atcagcaggt aagctccgaa taggagaaac
    12481 ttcaacgact attcctcttg agggaagtac actacaagct attggtagtg gaagtgggta
    12541 gaccttaacg gataatgccg aaggataaga tatagtctgt gcttacgtga aagtgtaaga
    12601 agttcataag agaactgcat aggtagtagc gaacttatgt gaacgacaac ctcaaaaatg
    12661 ataaaagtta agaacttacg gttcttatat atgttattta aaaataaata taaaaaacct
    12721 tcaaaatact tgttttaagt aattgcatat tttaatatta tgataagtga tgaaaaatgg
    12781 aagttactca tggtagagga tatgcatata gtatgtcaaa tatagacatc cattattatg
    12841 gggagacatc tttggaatcc tagttatttc gttgctactg tattagaaaa tacagaggag
    12901 cagataggaa aatatattaa taatcagaaa aaacaagtaa agtgaggtga tagtagtgga
    12961 aaaagcttat aagtttagaa tgtatccaaa taaaaaacag caagagttaa ttaacaaaac
    13021 ttttggatgt tgtagatttg tatataataa gtatcttgct aaaagaatag aagtttataa
    13081 aaacgataaa gaaactttta cttataaaca gtgtagttct gatttgacca atttaaaaaa
    13141 agaattaaag tggcttaaag aacctgacaa attttcacta caaaacgtct taaaagattt
    13201 agataatgca tataaaaaat tctttaaaga aaaagcagga tttcctaaat ttaaatcaaa
    13261 gaaaattaat agattttcat ataaaactaa ctttacaaat ggaaacatta tgtattgtgg
    13321 tcaacatata aaactaccta aacttggtat ggttaagata agggataaac aagtacctca
    13381 aggtagaata cttaatgctg ctatatctaa agaaccaagt ggtagatatt atgtatcatt
    13441 atgctgtact gatgtagata ttgaagcatt tgaaaatact aataatcaga taggtttaga
    13501 tttaggaatt aaagaatttt gtatctcaag ttgtggagaa tttatagaaa atcctaagta
    13561 tcttaagaag tcattaaaca agcttgctaa attacaaaga gaattatcga gaaaaacaat
    13621 cggtagttta aatagaaata aggcaagatt aaaagttgca agacttcaag aacatatagc
    13681 taatcaaaga aatgattttc tacaaaaact atctactaaa ttaataaaag agaatgatat
    13741 tatttgcata gaagatttac aagtaaagaa tatgattaga aatagtaaac tatctcgctt
    13801 aatttcagat gtatcatggt cagaatttat tcgtcaatta gaatacaagg ctaattggta
    13861 tggtagacaa attgtaaagg taggtaaatt ctttgctagt tcacaaatat gtaataaatg
    13921 tgggtataaa aacgaggaag ttaaggactt aaatataaga gaatggattt gtcctagttg
    13981 taatgaaact cacgatagag atataaatgc aagtataaat atattaaaag aaggattaag
    14041 actaataacg attcaaaata aataacatat gtaagaaccg taggaactac ggggatagcc
    14101 tgtggagaat tagtaagaca tattttagta tgcaaaattc tatgaagcag gaaccctgtg
    14161 actttagtca tgggaggttc agtttatttc aaataatatt ttacgtaatc catctatgtt
    14221 aattggatta atagcagcat ttggtcttgt actacagaag aagaaagcat ctgatgttat
    14281 aaaggggtca ctacttgcag ctttcggaat tataattatg gagactggaa caggtatgtt
    14341 agttagttca atagcaccaa ttaatggagc tttccaaagt ataagtggtg gtgcagtaac
    14401 aaaaggttta agtgatgtta cttttactgc aagttatggt ggaattatag gtttagcaat
    14461 gtttgcgggt ttagctattc acctaatgat agcaagattt actcctatta agacaatctt
    14521 cttaacaggt cacatgcttt attggttccc attcatattt gtagcttcag gagttgaagc
    14581 tggattaaat ggtggagtat taataacttt tgcagcagta ttatcagcac tctattggtc
    14641 aataatgcct tggttattaa gaaaatatgt gtttgatgtt ataggagatg attcttttac
    14701 attaggtcat ccatctggtt gtttagcact tatatcagga tttgttgcta aattagtagg
    14761 aaataaagaa aaatctacag aagatataaa catacctcaa agtttatcat tttttagaga
    14821 aatatctata agtggtggaa tggcagtgtt tttaatgttt atagttgttg ggatagtaat
    14881 accaggtgcg tttaaagata gtaatgagtt tattggaacg tatgcaataa agcaaggtct
    14941 ttcttttgga gcaggtctta taataatgct tcatggggta agaatgctaa taaatcaaat
    15001 aatgccagca tttcaaggta tatctgaaaa agttgtgcca aatgcactac ctgcttttga
    15061 ctgtccaata ttatttaatt ataaaccaaa tgctgtatta ataggattct tagttgctat
    15121 gctaacatct acagctatga ttttaatata taactacttt aatgtattta atttgctact
    15181 tataccactt gttataactt cattctttga gtgtggagca gcagcagtaa taggagaatc
    15241 acaaggtggt atacgtggag ctataatagg tacagctata gctgcaatat ttatggtagt
    15301 tttagtagga atatctgctg taatttactc aggaactatt caaaattgga tactaatatt
    15361 tggaggtaat gacctttcat tatttggtat aatcagtagg tttataggtt cactatttgg
    15421 aggaatatta tagatatgaa atttaaatac atagatgaga taagaagatt aattgatata
    15481 atagaaaacg aagaaaaagt caatatggaa aaagcagtac aaatctttgt tgaagcaata
    15541 gaaagtaaaa atgctatatt ttcatttgga gcttcacatg caggaatatt aacagaagaa
    15601 ttattctata gagcaggtgg ctgtgttctt ataaatccag tatttgcaaa atctctaatg
    15661 ttagatacag cgcctataac tcacacaagt aagatggaaa gattagaagg atatggtaca
    15721 gctctagctg ataaaactcc aattaaaaaa ggagatgtag ttatagttca ttcagtatct
    15781 ggtagaaatc cagtaagtat agagtttgct atgaaagcta aggaaaataa ggcaatagta
    15841 atatgtataa ctaatttaag ttactcaaaa agtgtatctt caagacattc ttcaggaaaa
    15901 aaactttatg aagtatgcga tttagtgata gataatcatg gtcaaaaggg agatgcctgt
    15961 gtagagatag atggattaaa ccaaaaagtt agtccaactt ctactgtaat agcaactact
    16021 gtgatgaact ctattatagc tcaagctact caggaattag ttaataaagg gctaaagaat
    16081 cctccgattt tctatagtgc caatattgat ggtggagatg agttaaataa gaagattttt
    16141 gatgaatata aaagtgtaat tcattatgaa tattaaggtt aaaaaaatat gttaatgaac
    16201 tttgaagttt atcaacaaag aatattaata atatataata aatgctatca tttaaaagct
    16261 gtaggtaaaa atctacagct ttttattatt gtagattaaa aagatgcgta attaaatttt
    16321 aaattggaga aaataaattg gaaggtatca attataaata ttagaaacgt tgtcatagaa
    16381 aaaaactata ttaaaaaaaa gtacatagaa aaaactgatt agacaataaa tacatgcttt
    16441 gataatattt taaatggaat gaaaatgtgt agaattataa tgaaaaaaga aaataaaaat
    16501 gaaaaaagaa aataaaatgg agggaataaa agtgggtatg ttaaaaaaat tatgttcact
    16561 agctatggta gcaattatga ctacaacact tataacaggg tgttcaagtg gaaatggaaa
    16621 agattcaaaa aaggatggcg aaaaagaaaa actagttctt tggatgccac cagtagaaaa
    16681 taatatgaag gaagtttggg accctatttt agataaattt gaggaaaaaa ataactgtga
    16741 agtagattta cagataattc cttgggataa ttattctgaa aaatttgcaa cagctataag
    16801 tgctggcgaa ggtccagatg taggatatat gtatgcagaa atgtatccac agtttataga
    16861 aagtggagca gtagaagatt tgactaacta tgcaactaaa gaggataaag agcaatctat
    16921 ttatataaaa acatctgaaa tgatgggtgg aatgtatggt atgccattcc aagcagcaaa
    16981 tccaggggta ttatactata acaaggatat tttagagaaa ctaggagaaa aacctcctaa
    17041 aacatgggaa gattttaaaa gaatttgtaa aaaagcaacg caagatactg atggtgatgg
    17101 aaagatagac caatggggat tagctcaggg atggggagct aaaacttttg gtaacttaaa
    17161 ctggaactgg tatccttatt tatggcaagc tggtggagat atatttaatg atgatttaaa
    17221 atcggttaaa tttaatgata agagtggttt agaagcagct aatttcttaa aagaattaca
    17281 agcatatgtg cctgaagatt ctttatctaa agatagtaat gaaatgatag aaagcgtatt
    17341 tggaccaggg aaagcagcat ttacaataat gttatcttct gctgcaacaa gtgtatttga
    17401 tgaatcattc ccggatttaa attggggatt tgtaactgga ctagaagata agaaagcagc
    17461 aacttttgga gcagtagacc atttatcttt aatgtcatct gctaaaaata aagaacttgc
    17521 atacaagtta atacaacata tgttaagtgt tgaatcaatg acagaatttc ataaagcaat
    17581 accaagagca ccaataacaa aaggtgaacc atatcaaggt gatgaaagat tcaaagaaat
    17641 ggtggaaaat gacaaaaatg tatatagacc attagtagta ggacctcatg gagttgaaat
    17701 atatgaatat ttatggaaag aacttcaaac tatgatttca ggagataaaa ctccaaaaca
    17761 agcgttagat gatgctgcaa aatattcaaa tgatttatta gcacaataaa agtttaaagc
    17821 tgtaatatgt tgtaaaggac tttacagatt aaaattagca ttgtatttat aaatacaatg
    17881 ctaatattta tattggagag gataaaatgg aaaacttagt tagagagttt gaagaaaatt
    17941 caaaaagaaa aaaaacaaaa ttaaatatta aaccatatat gtatatattg ccattgggaa
    18001 taattttagt ggcgttttat gtgataccaa taataatgtc aatatacttt agttttacaa
    18061 agtataatat tattagtcca gctactttta taggtttaga aaattataaa aaattattta
    18121 cagatgaaac attaaaagta tctattataa atactattaa atttactgtt gttgtagtac
    18181 cttgccaaac tatattatca ttgattttgg ctgtttggat tacaggaaaa ggaaatagta
    18241 aaatagcttc atttgctaaa ggtgctatat ttataccagt attatcatct atggttttga
    18301 taggtatggt atggagggct ttattgaatg gagaaggttc tattatatat caggtattag
    18361 gtgcctttgg aatagaatca tctaaacttt taggagatag taagacagca ttacctacac
    18421 ttatgtttat atctatgtgg aaaaatatag ggtattttat ggtaatttat atttcagcta
    18481 taatgaattt accaaaacac tgctatgaag tagcgaaggt tgatggggct acaaaacttc
    18541 aagaatttat aaaaataact gtacctttat tgaaaccaac tacaataatg gttgtatttt
    18601 tagggtcgat atggtcatta caagtatttg acttaattta tactgtgaca ggtggaggtc
    18661 caggtatatc tactatgagt atagttatgc atgcatttaa cttaaacttt aaaaacttta
    18721 attctggata tgcaatgact gtagcaaacg tattattttt gttaatagca gtagtttcga
    18781 ttttacaaaa taagcttgta agacgagaca attcagattt ttagaaaggt aggtataata
    18841 tgaaaacagc aagaagatta ttaagtgatg gtttgctttt atttatagcg tgtgcaagtt
    18901 tggtaccttt tatatacatg ttgataatat cattgaagat aacatataac tcatatagtt
    18961 tggatatatc tttttcaaca gtaacccttc aaaactatat agatattttt actaaaaaag
    19021 gatttgcaca atattttttt aatacagcaa tagtatcttt ttcaggtgta ttattaaatt
    19081 tagtatttag tacattagca ggatattctt ttgcgaagat ggattttaaa ggtagtgata
    19141 agttattttt atttatgata atgactttaa ttataccttc ccaagttaca atgataccac
    19201 tatatataat aatgaaacac ttaggatgga taaatagtta tcttgcactt attatgccaa
    19261 taccaactgc atttggcgta tttataatga gacaagctat tttaggagta ccaaaagagt
    19321 tattagaatc agcaaagata gatggttgtt cggattttag aattttaata caaatagtgt
    19381 tgcctttaat taaaccagca ttaattacac tagcaatatt tacttttatg ggagcatgga
    19441 acgagtttat gtggcctctt atagctacaa ctaaagatac aatgagaaca ttaacagttg
    19501 gattatctac tcttaagaca ttccagataa ctaattatgg acagatgatg gcaggggcta
    19561 caataacatt tttacctcca tttattttct atttgatttt acagagtaaa tttgttgaag
    19621 gtgtgtcttt gtctggtata aaaggttaaa tagtctaatt taataatata taaagaaact
    19681 tatataaata tggaggaatt taaactatgg aaatttcata tgtactgaaa gattgcacat
    19741 tcaaacacaa taaatactca gttgtagaag ctgaaacttg gaaagataag gatttggata
    19801 ttgtagtagc taaaggtgaa aaatttgcat ttcaaattat gttaaaagca acagaagaat
    19861 ttaattgtac aattgataaa agtagtgcta tatcatggaa aggcctggga aatagagtaa
    19921 ggttagcatt aaatatgcct aatagtttag aaaataattt tagtataaat atattaggat
    19981 atgttcaaga tgatacaaag gcatttgtga atgatgctat tttaagggat aaagatgtgt
    20041 tagtagagca atatttgcct caaacatttt ggattgaagg tcaagtacca gaagattttg
    20101 aagaaaataa ccttgatata ggtattgata tatttaaaag ctttggatat gaagacgaag
    20161 aaaaagtttg tacaattgat gttcctgtaa aagtaagaaa tgttgtgcta aagcctttag
    20221 atgaaagcaa gttcttttta gatttatggc aacatccaag ctgtttagct agaatgtata
    20281 aagttgagtt atggtctgat atacattttg aaatagtcga taactattta aaagaattag
    20341 catctttagg agaaaaagtt gcaacagtta tagtttcaga ttatccatgg gcagggcaaa
    20401 gttgttataa agtttataaa aatccatcaa acttatatga atataacatg gtaagtgtat
    20461 caaaaggatt ggatggaaag attaaatgta actttgagag tatggatagg tatataagca
    20521 tagctgataa gtataaaatg gctaaggaga tagatttatt tggtctatta ggtaattggt
    20581 gtgctggtga gtttggaaat cctgtagaag gttataagga ccctataaga gtaagatatt
    20641 ttgatgaaaa ggataaagta tttaaattta taaacaatac aaatgattta aaagaatata
    20701 taggattagt attaaatcat ttaatagagt gtggattatg ggacagagta aggattatag
    20761 ctgatgaacc aaataatcca gaagtagtca aagagtgtat agaatttata aattctactg
    20821 taagcactca tcaagttaaa tataaatcag caactcacga ccaaaacttt ttagacagag
    20881 ctaaagatga aattgatgat atgtcaataa atttaaaact tactatacaa aattataaag
    20941 atatagaaag tcttaagaaa aaaatcaatg acaagggtgg gatattgact tggtttgtat
    21001 gctgttttcc agagaaacca aatagttttt taagttctcc ttttgtagaa aatagaataa
    21061 taggatggta tacttattac tttggtcttg atggattttt aagatgggac tataatttat
    21121 ggacagaaga cccttggaaa gattcaagtt acaaattccc tatttggaaa gctggagata
    21181 tgttctttgt ttatcctgga aaagatttaa agccagttag aagtgtcaga atggagaatt
    21241 taagatttgg aatacaggac tttgagttat ttacaatgtt agaaaaagaa aagggaagag
    21301 agtatataga agttgagctt atgcaagaat tattaaataa aaaagaaaat gctgaaatta
    21361 aaggttttgg tgacatagaa ctaggatatt cacttgataa ttggggatat gataaagtta
    21421 aaaaatatgt attagagttg ttagacagag tataaaaaat ataagagtgt ctcaaaatga
    21481 actttttagt tcatgaggca ctctttttgt atgaaatcaa tatagtttca ttgtttcaac
    21541 aatgaaaaat aggattattt ctattctaag acagcccttt agttttttag ttgtattcaa
    21601 tgttttaaaa ctaactataa acgctataaa gtttataaat gacaataatt atatataaca
    21661 tgatgtactt taatttgcta taatagggat tgaataatat tatatggaag ataacattgt
    21721 ttggggggat taatataaaa agaataggta ttattataat gtttttttta agtatatctt
    21781 ttattggatt ttatcttgta ataagagata acagtgatac agttaagatg caacgaggga
    21841 taaatatagg taatgcacta gaatcaccta aggattttcc gtgggatgta aaaatgtcaa
    21901 ataagttttt tgatgatata aaagatgcag gttttgacac agtacgtata ccagtaaggt
    21961 tttctgatta tacgtcagat tctgataatt ttaaaattga tgaagaattt tttaaaaaga
    22021 ttgataaata tgtagattat gcattggata aagacttaat agttgtgttg gatttacacc
    22081 attttgaaga aattatgaaa gaaccaagag ttcataaaga aaagttttta aaaatatggc
    22141 aacagatagc taataggtat caaaaatatg ataaaaaatt ggtatttgaa ttattaaatg
    22201 aacctaaaga aaatttatat tcacagttac taaacgaata cattgaagaa gcaataaaga
    22261 taattagaaa aactaaccct aaaagaacta ttatagtagg accatataat ttctatcaaa
    22321 ttgattattt gaatgaatta aatattccta aagattctaa tatagtagtt tcctttcact
    22381 attacgagcc aaatgatttt gcatttcaag gaaatatata tcataaggga tttgagcact
    22441 taagcaatat tacttgggaa ggaacaaacg aacaaatgga ttatttaaaa aaaaggtttg
    22501 atactgtgga aaattgggca aataaaaata aggtaaaaat cttcttgggt gaatttggaa
    22561 taacaaaaga ggcaccagaa gcttcaagaa gagcatggat aaaagctgta agagaagaag
    22621 ctgaaaaacg aaacttttca tgggcttatt gggagcttgc atctggattt ggtatataca
    22681 atcaaattga agggacttgg gatagagata tattaagtgc attaatagaa aagaggtgat
    22741 tttatgaaga aaaattcaaa aaagatactt ataactttaa ctattattac taatgtcata
    22801 tatatattgt ggagaatttt ttacacagta cctaaagaag aagggaagtt tgccttaata
    22861 tgtgccataa tacttctttt tgtagagata atgggcatga tggaaatgtt tgtgcattat
    22921 tatggtatgt caaatattga gtaccctgaa aaaccaatca taagtgaaga actttatcca
    22981 catgtagatg tattcattgc aacatataat gaatctgttg atttggtgag aaaaactgta
    23041 aatgggtgta ttcatatgca gtatccagat aagaaaaagg tacatatata catatgtgat
    23101 gatggaaatc gtgaagaaat gtgtattcta gcagaaaaaa tgggtgtaaa ttacataact
    23161 agaactgaaa gagaaggagc aaaagctgga aatttaaata atgcaatgca acatacaaat
    23221 tcccctttga ttgctacatt tgatgcagat atgataccaa tgcatgactt tttaattgct
    23281 acagtaccat actttttgaa aaatgagcaa gctaaaaaag atggagaaaa agaggagtat
    23341 gaaaaggttg gttttgtgca aactccacag agtttttata atccagactt gtttcaattt
    23401 aatctgcact ctgaaggaag gattccaaat gagcaagatt atttttacag agacattcaa
    23461 ttggctagaa ataggacaaa ttctgtaatt tatggtggta gtaatacagt tatttcaagg
    23521 gaagcacttg aagaagttga tggattttat acttattcta ttacagaaga ttttgcaaca
    23581 ggtatcttaa ttcaaagtaa ggggtataga tgttatgcta ttccagaagt acatgcatca
    23641 ggtttatctc ctacagattt aaaaagtctt attaagcaac gtgaaagatg ggcacgtgga
    23701 tgtatacaaa ctggtagacg tctaaatatt ttgtttagga gaggtttagg tttttggcag
    23761 aaaataagtt atatttcttc aattacttat tggtatgcaa gtataaaacg ctttgtatat
    23821 ataatggcac ctattttatt ttctgtgttt aatgtgattg tagtaaaatg tacgttactt
    23881 caagtattgg tattttggtt gccaatgtat attttaagta gtttatctct taaaatattt
    23941 tctcaaaata taagaaatac tagatggacc aatatatatg aaactataat gtttcagtct
    24001 ttaatgccag cagtaatact tgaaacgttt gcaatatcta aaaataaatt ttcagtaaca
    24061 aataagagta aattagaaga aaatagaatg tataagtttt tacagggaat accttatttt
    24121 atttacatgg tcttatctat cataggaatt ttaaaaatgt ttgtagcaat atttaaaatg
    24181 agttcaatga catattcagt tgtattattt tggttgattg gaaacctttt taaccttgtt
    24241 atggctacat tatttatatc agggagacag cagttaagaa agtctgagcg ttatattgct
    24301 gaaattgatt ttaagttaaa gcaaaattct tatgttcttt cttcaaaaac aattgatata
    24361 tcagaaaatg ggtttgcatt tttgctagaa aatccagaat atatttcccc agaagaagag
    24421 tttgaggtag agtttagaga aaaatctgga aatgaaatgt atatagctaa tatgaaagca
    24481 aagattgtta atgttgtgga agtaaattca aagtggaaat atgcagctta tattacacat
    24541 attgaagata gtgaaataga taattggatg tgtattgttc acgatagaat acctacttta
    24601 ccaatgacaa tatctaatca actaggtttc tttgatgatt tgcaaattaa tgtaaaaaaa
    24661 cgtattgaaa aaactagaac attatcacga agaagtccaa gaatcaatat gaattttcag
    24721 atggatataa aaaatacagg taaattaaga atagtgaatt ttaattatca atatgtatta
    24781 ttaaattttg agaataaaag tatttatcct aaagaaatag cattggaaat taatgaaaat
    24841 attgtgttag aatgtgattt gtgtgagggt aaaattgatg aaagaggtat cttatataaa
    24901 gtaaataaca ttgacagcat aatgcaaaat ttctttttaa gagatgaaat gatggattgg
    24961 atattacaaa ataagaaaat tcttgattca aagcctagtg aaaagaagga aaaaagtata
    25021 gatgagtttg aacccatgga atatatttag gagagatgaa atgaagactt taaaagtgtt
    25081 tttttgttct acaaaatatc ttattttggt gtttattttt tttataaata ctacttttat
    25141 aagttcagca acaagtgata aaattttaga tttatccttt aaaaagatag agactgactt
    25201 aagttctaag attacatatg aggatacagg tgtaaaaata gaaacggata gttctaaaag
    25261 cgataaggaa cgttatttat atatttacca aaatataaaa gaaaattgga gcatgtataa
    25321 taatttttat attgaaattc aaaataaaaa taaaagttct cagagaataa atttaagcat
    25381 acaaagtaaa aatatgcttg aatttagatt aaaagaaggt agtgaagtat ttttagaagg
    25441 taaaaatata atatattcag ataaaataaa agaaggatgc atagaagtac caggtgaatt
    25501 tgaaggcaaa atttatgtga actttaatag ccttataaat gaggaaagta atgttgtgct
    25561 ggactcaaat atgctttcaa acattgttag ttggggaatt acgtttattc catctgatga
    25621 agaacataat attgttatta taaaaaagat atctttattg tctgaagaga aattaagatt
    25681 tttaaataat attaaaataa ttggcgatga agaagtacaa ataccagtat tgggtcaaag
    25741 tataagtcag tatgaggtat taggtcttaa aagtgattct aaaattaagt actctcttat
    25801 gggaaaacaa gataatgtga gtatatctca aaacggtaaa ttaacattaa gtaataaagc
    25861 caaacctgga caaattattt tacaagttaa tgttgatgat aagtttaaaa ttggaaagaa
    25921 aataacatta actgaatctt ggagtattaa taaaaaagat aaggatggtg ttccatatac
    25981 attagtatct cctgagcaat caccaacagt acaagatatg aaaaaaataa attttatgaa
    26041 taatatcata acgtttgttc gaattttatt tgtatctcta gtaataatat gctttggaat
    26101 atatttatat tggaaaaaat gttcaaaaac taagtaaaga gaggaggtta gattgtgtta
    26161 ttttcaagtt taattttttt attttatttt ttacctataa ctttggtttt atattatgta
    26221 tttaggttta accgaacgat acagaacatg atattgcttg ctgttagttt atttttttat
    26281 gcttggggag agccaaaatt tgttgttatc atgatagttt ccataataat gaactatata
    26341 tttggtttac tggtagatag atatagggaa agtaaaataa aagtaaaagt ttttttagtt
    26401 ttgatgtgtg catacaatat aggtgtttta tttatattta aatatctagc ttttgcgcta
    26461 agaaatatta gtgaacttat tagtactgaa ttgactatac ctaatattat tttacctata
    26521 ggaatttcat tttttacatt tcaaggaatg tcttatgtta tagatgtata tcgtagacat
    26581 ggagaagtcc aaaagaatcc tttttatgtg ggactgtata tagcattttt cccacaatta
    26641 atagcaggtc ctatagttag atatgagagt gtggcagaac aaattctcaa tagaaaagaa
    26701 acttggaata aattttctat tggtacttgc aggttcataa caggtctagg taaaaaagta
    26761 ttaatttcaa ataacatggc tatagtagca gactatattt acactatgaa tagtcaagga
    26821 gaaatagctg catcacttgc atggcttggt tcaatagcct atactctgca aatattcttt
    26881 gatttttctg cttattcaga tatggctata ggcttaggtc ttatgtttgg ttttaaattt
    26941 gaagagaact ttaattatcc atatatatca aaatcaatta gtgagttttg gagaagatgg
    27001 cacatttctt tgggaatgtg gtttaagagc tatatatact ttccgcttgg aggttctaga
    27061 gtagcaaata aagatattat gattagaaat atgtttatag tgtggttatt cactggaata
    27121 tggcatggag cagaatggac atttgtaatt tgggggattt taaactttgt tttcctaatt
    27181 atagagcgat ttataatgtt tgaaaagatt gaaaatcaca attttataaa acatatttat
    27241 gctttattag tagttaattt tggatgggta ttgtttaggt cacctaattt aaaagaagca
    27301 tataattatt ttaaagctat gtttggaggc aatggagcta tatggagtga ttatacatat
    27361 atgtttttaa aagaatactg ggttttcttt atatttgcat ttatttttag tgtacctatt
    27421 gcaaagaaaa tcaataagtt tgttgttgaa caagctaaat atagtatgat atttaacgta
    27481 ttttatccaa tctcagctat tttattgttt tttatttctg tgacatattt agtaactgga
    27541 agctataatc catttattta ttttaatttt tagttgggag gaaaagtatg aatagatttt
    27601 ttaaagtaag attaataact gcaattatgt tcttaattat tttattcgct ttctctatct
    27661 ttaatgtttg ttattctgga aaagatacga tacaggaaat aaaaaattca atagctgaaa
    27721 aaagtagttt aaaagataca atatcatcta ttgataatac agtgaatgac aaagtaatat
    27781 acaaaaatac gttcattgaa acttatggct atttacaaaa attaatgggt aaaaatgagt
    27841 tttcaaaatt tagtgttgta aaagatactt ctggaaagat gcattataca tattttgcta
    27901 aagctccaaa tccagttggt gtgatagcag atagggtaag aaaattttct gatgaaatgg
    27961 aaaagcaaaa cactaaattg gtttacctaa tgactccaga taagtatata aaaggagtga
    28021 caaaatttcc aaaaggaata ccttattctt atagtaatga gacagcagat aattttttaa
    28081 atcaactaaa aaagtataat gtggactata ttgattttag agaaaatatt ttaaagagtg
    28141 gtattccaaa agatgattta ttttttaaaa cagaccatca ctggaaagta gaaacttctt
    28201 tttgggcatt tggagaatta gttgagcaac ttaataaaaa atacaatatg aatttagatg
    28261 aaaatcatta ttatagagat aaggacaatt ataattcaat tgtatatcct aagtcatttc
    28321 ttggttctat gggaagaaag actggtatct tatatggtgg tatagatgat tttacattaa
    28381 tttatcctaa atttaagact aattatactt attatacaga ttctaaatct caaaaatttg
    28441 aattaaaagg aaggtttgaa gagagtttaa tattatcata tccttttaat gcagaccttg
    28501 atttaatgga tggtcaatca gataagtatt ttacatattt attggggaac agaccattag
    28561 ttaaaataaa aaatatagaa aatccagatg gattaaaagt gctgtttgtt aaagattctc
    28621 taattgtacc aacagcagca tttttttcct ctgtttgttc atctatagat atgatagacc
    28681 ctagatatta tgatggagat atactagaat atgcaaaatc ccatgactat gactttgttt
    28741 ttatatctgt atatccccaa aatcttacaa aagaattttt tccgttttgt gagtaaattt
    28801 ctaaaaaagt tttctgataa aataaatggc taactggtaa aaagttagcc atttattttg
    28861 agtgttattc taagaaatat tttttttact aaatacttct ttatctattt ttccaagtga
    28921 ttttcctaca gtaattgatg ataccatagc accattaaca tttatcatag tacgtcccat
    28981 atctagtata gggtctattg caagtatacc accaactaat ggaaaataag aaccaagacc
    29041 aactccagag ataacaactg aaacggccat tgtagcagtt cctggaagac cagctattcc
    29101 aaacgaacta attgttataa caattaacaa cataacataa aagctcatat ccatgtttac
    29161 tccagccata ttggcaagtg ttacagccat taaagcagga tatatacctg cacaaccatt
    29221 catacccata tttgcaccta aacttgctgt aaagcttgat acaccctcat caactccgtg
    29281 attttgtact agactttcta tcgttacagg caatgttcct aaactagaac gtgaagtaaa
    29341 tgccagaagt aaagcttcag ttgaattttt tatataagta atgggattta gaccatttaa
    29401 agttataaaa attaaatgta taataaataa tattgcaact gatatataaa gagctaatat
    29461 aaactgtaaa acagatacta ttgaactaat accttgtgaa gttattgtat ttgcaagcag
    29521 agcaaccaca gcataaggca taaatttaat aacagtcata gacacactta caattatttt
    29581 gtaagatgct tctataaaat ctataaatgg ttttattgtc tcaaaatgtt ttttacttaa
    29641 tctctttatt gaggtagcta taaatgtagc aaatattatt gtagctacaa tatttccatt
    29701 tgccatagcc attacaggat tagatggtag taatcctctt aaagtatcca caagagagtt
    29761 tatttcttta agttcttgat tttcaactaa agtaggcata ttagctccta cacctaactt
    29821 cattatattt gcaacgataa ttccaacaat tgcagctata gcagtagtag caagaagcat
    29881 acctaaagat ttaaatgtca gagttccaag attgttatct ttcatattta taattacttt
    29941 tataatggat aagaaaacta aaggtactac taacattttt aataagtcca taaatccaga
    30001 accaaatagg ctataccact tacttacttc ttgtagccaa gtgacttgag ttgtatcatt
    30061 aggaaaacca gcaaaagctt gtattatgat tcccaatatg agtcctagta ctgtagcata
    30121 tattgttctc aatgaaaatt ttattttttt cttttcaaat tgtctaacaa taaagaacgt
    30181 acctagaagt aatattatga aaaaaattgt tttaaaatct gtaatcataa gaaattgtga
    30241 taaaaatgaa ctttccaata tttttctcct tttatttaaa aataaatttt tctaagttta
    30301 aatgatatca atatattaaa aaaatgtcaa tattatatca caatttactt aaatagagta
    30361 aaacaagttg attttgaaaa atgtgattaa gtacagaaaa atagggtata ataaatgttt
    30421 aaagaatttg aattgtggta agaaaataaa aaatagcttt tataagattt gatttcaaat
    30481 taaaatatgt taaataaata actaaaaatt attataaaaa atgttttcat agaatatata
    30541 tcaaatgaaa agcttaaaat aagtgaagaa attaactaga catcaaagga gagataaaat
    30601 gagagtaata ataattggtg gtgttgcagc tggtatgagt gctgcagcaa aattaaaaag
    30661 aataaaacct gagtatgaag ttgttgttta tgaaaaaact gaaatagtat cttttggtgc
    30721 ttgtggatta ccatactttg ttggtggatt ttttaatgat gctgatgaat tattagcaag
    30781 aacaccagag aaacttagag aagctggaat tgatttaaat atatttagag aagtcgttga
    30841 ggttgatagt gaatctaaga aaataaaagt aaaaaacata aaaacagatg aaatatatga
    30901 agattactat gataaattga tgatagcaac tggagcaaga agtattatgc ctcctataaa
    30961 aaacataaaa ttgaagaatg tttctacatt aaaaagttta tatgatggag aatatctaaa
    31021 aaaactttta agtaatgaag ataataaaag agtgacaata ataggagctg gttttatagg
    31081 gttagaagca gttgaggcat gtaagaaatt aggtaaagat gtagatgtaa ttcagttaga
    31141 agatagaata ttgccacaag tatttgataa ggaaatgacg gatgtattag aagaagaaat
    31201 aaatagacat aatgttaatt tgcacttaga tgaaatggtt gtagaacttt gtggagaaga
    31261 taaagtagaa aaagttataa caaacaaagg ggaaatagat acagatgtag taataattgc
    31321 tactggcgtg agacctaata ccgagttttt gtcaaatact aatataaaaa tgctaaaaaa
    31381 tggagctata gtagttgatg agtatggaag aacttctgta gaagatatat actctgctgg
    31441 agattgtgca actataaaga atatagtaag taatgaaaat gtatatgttc ctttagctac
    31501 tggagctaat aaattgggta ggatagtagg agaaaaccta gcaggaagag aagtatctta
    31561 tcaaggttca ctatcttcaa gctgtataaa aattatggat atggaggcag catcaactgg
    31621 aattacagaa aagcaagcta aagatttagg cataaatgtc aaatctaaat ttatttctga
    31681 ttataatcaa actcattatt atccaggaag aaataaaata tatgtaaagc ttatttatga
    31741 tgcagataca aaagttattt taggcggaca agtggctggg tttaaggatg ctgtccaaag
    31801 agcaaatgta ttggcagctg ctatctttgg aaaaatgacc acaaatcaac ttggaatgtt
    31861 agatttatgt tatgctccac catttgcaag aacatgggat gttttaaatg tagctggaaa
    31921 tgtatctaaa taatatttag attatagcta atatagttga caagcaatta agggaatgaa
    31981 tttacctaaa ctatttttat catggtaaaa ttcattccta aatttttatt ccaaattttt
    32041 attccaaatt tttagaaata aggattccat taaattattc atcaaaattt aaacgcaagc
    32101 ttaatctatc ttctccaagg atagtatttt caaaaacatt agtagcattt tctaaataca
    32161 tactaggtat gtctaaagaa ggactaaaat gagtcagtaa aagttgtttg acatttccaa
    32221 gttttgcaag attagcagct tctctaaaag tcatatgttt gtttctaaca gcttttgata
    32281 tatctaaatc atcaccatac atggcttcac atataaataa atcactatct tttatgaaat
    32341 ctggtattga ttctataggt cttgtatcgg ttgtaagact tatcttaact ccctttctca
    32401 attctcctaa gaccatatct ggagtgtatt gttttgaatc taaaactata ttttgacctt
    32461 cttggagttt gttccataat attttaggaa cttcgttttt agttgcctta tctatatcaa
    32521 atttagggtt tcttctaaaa ttaaaactgt atcctaaaca ctctatagag tgttctaaac
    32581 tgattgttga aatttctaaa tttcttaaaa ctttattatc taaagaaaaa ttgccttgag
    32641 ggttttctat aatttttaaa gtgtatggta catattctac taaatttctc atagaacgta
    32701 tacaatcgac tattccaact ggaccaacta tagttaaatc acttgtacga ccactatttc
    32761 caattgttga taaaagtcct aaaagtccaa atatatggtc accatgtaaa tgggttatac
    32821 aaatcaagtc tatatcttta aagccacatt tttttagctt catagatacc tgagtacctt
    32881 caccacagtc aattagtatt tttctacctt tatagtttat aaatacagag gatagaaatc
    32941 tgtttggcat aggtacattt ccaccacatc caagtaaagt taaatctatc attttttccc
    33001 ctttctaaaa ttaacacaaa tctgttgttt gtttttatta tgatatccta ttataattat
    33061 tttaacatta aatataacaa taaatgtgta tttgagtcaa gaaatattgt caaataaagt
    33121 ttttatatag aaatgtataa aaatttggaa aacaaaaagt gaaaattata tttaggagca
    33181 tttaaaggag gaaaatttaa tgaaagtatt aaagaaaatt actattttgt cattaattac
    33241 attaacctta gttggttgta gtaacggaga agataaaaaa gtggttgaag gttctaagaa
    33301 aattcaaaat tctaaaaaag atgaacagcc tataatagta cataaagatg caaatatatt
    33361 gaaagatagg tatgagccac caaaaggatt taaaagagtt gatgtagaaa aaggtagttt
    33421 tgaatcattt cttaggaata ctaagctaaa aaattatgga gagaaagtaa agtattatga
    33481 tggaagaact aaggaatcaa aaggtattta tgatagtgta tttgatgttg atattggcaa
    33541 tagagatttg catcaatgtg cagatgcaat tatgcttatg agagcagaat acttgtatca
    33601 gaataaacta tatgatgaaa taagttttga ttttgttgat ggttttaagg cgaagtattc
    33661 aaaatgggca caaggatata gaatttcagt aaaagatagt ggttcaagct ggtataaagc
    33721 aactgaatat tcaacatctt atgagagttt tagaaagttt atggatatag tgtttgcata
    33781 ttcaggaacg ttatctcttg aaaaagaatt ggagcctgta aaagttgagg atatgaaaat
    33841 aggagatgtg tttatagttg gtggaagtcc aggacatgca agtataatta tggatatggc
    33901 agaaaatgaa aagactggtg aaaaggtatt tatgatagcc caaagctata tgcctgcaca
    33961 acaaacgcaa cttcttatta atcgtaaaaa tccaaatttg agtccttggt atagtttaga
    34021 ttttgaaggt gatttgacaa tacctcaatg gacttttaaa agagaccagt tgaaaagatt
    34081 ttaaaataat aattttatat aataaaagaa aaatatagat gtgaaaaaat gtaattagat
    34141 taaaactaat tggatatgga caaaattaaa ttgatagata aatattaaaa attacactaa
    34201 ttaatcttac tatagtttaa tatttatcta aaaagtttta tgtaaaatat aaattttata
    34261 ttaaagctaa aactaatttg aggaggctaa tttatattga agattagaag gtatttaatt
    34321 ttggtaatta taattctaat tacaacaagt cagagtttta tttcttatgg gctagagcga
    34381 tttgaagaaa taaccatttt tcacactaat gatatacatg gaagatatgc tgaaggtgat
    34441 gaccatatac aaataggaaa tctagccaca ttgaaaaaag aaactccaaa ctcaatttta
    34501 gtagatgcag gagattgttt gcatggactt ccaatagtaa atatggatag agggaaaagt
    34561 gcaattgaat taattaaatg tgctggatat gactatatta ctcctggaaa tcatgacttt
    34621 aattatggaa aagatagact gtttgagtta tctaaaagtg ctaatttagg agagaatact
    34681 ttaaaatttt tatcatcaaa tatttttgaa aatggaaaaa aagtttttga tagtaatgat
    34741 ataaaagaaa tagatggaat aaaaatagga ttttttggac tctcaaccca ggaaacaaag
    34801 agcaaaactg gatttaaaaa tgtggaagga ttagagttta aaaatcctat agaaagtgca
    34861 acagaacaag taaatgaatt aaaaggaaag ggtgccaatg taatagttgc aatatgtcat
    34921 attggtacaa atagtttaag taagccaaat agtatagata tagcaaatga ggttcaagga
    34981 attgatttga ttattgatgg acacagccac actaagtttg aaaatggtaa acaagtgggt
    35041 gatacattga ttgtaagtgc aggacaatat ttagaaaata ttggcgagat aaaactaact
    35101 ttggatacta atgatgtaga aaatataaaa atagaaaata aatcagttag attaattgga
    35161 aaagaagaag cattaaagta taagcttgac tccgctgtaa gtaaaaaggt tgatgaaata
    35221 aaagaacaac aagaaaaaat attagataaa gttatagggg taactacaaa tactctagat
    35281 ggttcatatg aaaatgtaag gacaaaagaa actaatttgg gtaatttaat aagtgacatt
    35341 ttactagata aaactaaggc tgatatttct ttatttaatg gagggaatat tcgagatacg
    35401 atagaaaaag gcaatataac aagaagagat attgtagatg tatttccttt tagcaatact
    35461 atagttacca aagaacttac aggagcacag attaaagatg tattggagca tggagtaaaa
    35521 ctttatccag aaaaaagttc agcctttttg caagtgggag gaatttcata ttactttaat
    35581 cctaaacaaa aagaaggcga aaaaataaca aatattcaaa aagaaggaaa gccattagat
    35641 ttaaataaaa agtatgtagt tgcaacgaat gattatatag catcaggtgg agatgaattt
    35701 ccttgttttt caaaagagcc agtactaaag gaatttggaa atttagagag tgcagtcatt
    35761 gaatatatag agtacaaaaa agaaatatca aaaaatgtag atggaagaat tggtattaaa
    35821 tctaaagatg agttaataag caagaatcat gagagtgatt tgatattaag tgaaaatgaa
    35881 aaaaatatca atgataatga agagaatcta tctaataata taaaaagctc tgatagtgat
    35941 aaaaataaaa gcttagataa aacaagtgct agagaaagtt ctaatctagg aatatctaaa
    36001 agagaagcta aagaaaaatc tcctaaaaca ggagatttag gtttttcaaa tagtataatt
    36061 atatttatag tttcaagtac attgatatgt ttattgaatt ttaatcaaaa agagttaaag
    36121 gataaaaagt caaaataaaa attaatgagc aaaaattagt agatagtaat ttaattttag
    36181 ataatagtaa acagcaaagg aaattagtta tataaatact aatttccttt gttttatgtt
    36241 ttaacatgat tacttttaaa taaaattgta ttttatgaaa aataattaca ctaaatggca
    36301 tagtattatg gggattttta gtttttattc aagtaaatga aatcatatta acaacttctg
    36361 atatatttac aaattgataa aaaaatgatt ttattagtat gatataattt agctagtata
    36421 tatgatgatg gaggatatag ggatgaataa tatattactt ttggaagatg acaaatcttt
    36481 aaatagagga attagtttta aattaaaaaa agaaggatac aatgttttta gtgcatttgg
    36541 tatagaagaa gcaaaaaata ttttcgcaaa agaagagata tgcttaatta tttccgatat
    36601 aggtctacct gatggtagtg gttttgactt ttgtgaggag attagaaaga aaagtgatgt
    36661 ttacataata atgttgacag ctcttgatga agaggtggat attgtcacag gatatgattt
    36721 aggtgcagat gattatatca caaagccttt tagcttgatg gtattaatat caaaagtgaa
    36781 tgcgcttatg aaaagagtaa atacagtaaa aaattatact ctattagttt gtgatgattt
    36841 attcttttat tatatagaaa ataaattaat tataagaaca gatgataagg aagaagagat
    36901 aattttaagt aagacagaga caaaactatt aaaatatttg atggaaaatt ctatgcagac
    36961 attgactaaa gagcaactgt tagaatcttt atgggatagt agtggtaatt ttgtagatga
    37021 taatacgatt gcagtaaata taagaagact tagacaaaag gttgaaaaaa atccatctga
    37081 acctaaatat ataaaaacag taagaggggt tggatatatg tggggagaaa ggagtataaa
    37141 aaaatgctaa aaaatatgaa cctcaaagat ggtttaagtg tgaaagatga ttatataatg
    37201 agaagagtta ttgtatattc tgttttatct gtactaatag taacccttgt atttatactt
    37261 tttgaatata gcagattaca taaattgtat gaacatcaaa taaaaaacac tcaaaatatt
    37321 gctggaatat tgattgaaaa atatcctaat gatgaaatag atatagtaaa ttctatttat
    37381 aattctgatt atagtaaggt gtctactgga gaaaaggcat ttaagaaatt tggctatgga
    37441 ttggaaaata aaatgtcaaa tgataaaaat tttagcttat acttaaaatc tttttttaag
    37501 gaatcatttt ttattttttt aatgatgttt atagtagtta taggtataat atattatttt
    37561 ataagataca taaataaaag attgagtaaa atttatttta tagtagataa gatgtcacaa
    37621 gaaaactact tgaaggacac tactgagtca gaagaaactg gttatctagt agaatataat
    37681 gaatacttta aagaaggcat atttagtaag ataaataact gtctatatga gcttaataga
    37741 agtttaaaga taaagtttat taaattagaa aaagaaaaag aaagtgtaaa atcattagta
    37801 acagatattt cccatcaatt aaaaactcct ttagcatcct taaaattata caatacatta
    37861 cttatagaag aagaattaga agaagatgaa gccaacgagt tcttattaac caataaggct
    37921 tctataaata aattagaaaa tttaataaat tctttagtga acatatcaag gttagaaatt
    37981 agcatgataa acataaaaaa agaagataat gatataaaaa atactattct aaatgcagta
    38041 aaaagtgtta cccctaaggc taagagcaaa agtataacat taaatttaaa tgaatttaac
    38101 agtagaatta taccacatga taaaaagtgg actgaggaga gtatttttaa tgtattagac
    38161 aatgctgtaa agtatacaca ggtaaatgga gaaataaata tatctgtaga agaaactgct
    38221 aatttcttta aaattataat agaggataat ggcataggga ttgaaaaaaa tgagtttaat
    38281 aatatattta aacgttttta tagaggttct gctgatgaaa ttgaatctgt agaaggtagt
    38341 ggggtaggat tgtatttaag tagaaagatt ttagaagaac aaggtggaaa tattatagtt
    38401 tcttcaaaag taggaatagg gagcaagttt tctttgtttc ttacaactat gtaatattaa
    38461 atgaaaggaa aatgtaagcc tctacattta ttatataagt ataaacagct ccagaaataa
    38521 aaaattaata aaatatggag taatataact tagaatgaga ggataatttt atgaaaatac
    38581 tatatactga aaatttatca aagcattatg gaaaaggaga aagcttagta agagctttgg
    38641 acaatgttga cttagaaata aatgaaggtg aatttgttgc aataatagga aaatcaggtt
    38701 ctggaaaaag tacacttttg catatgattg gaggtcttga tatacctaca tctgggaagg
    38761 tgtatataga taataaaaat atatttacat taaaagaaga agaacttgct gtatttagaa
    38821 gaagaaaaat agggtttata tttcaaagct ataatttaat tccatctctt aatgtatggg
    38881 aaaatgtagt gttgccaatc ggtttagatg gtagagaagt agatgaatct tttataaaag
    38941 aacttttaaa atcattagga cttgaaaata aacacgacgt tttaccaaat acattatcag
    39001 gtggtcaaca acaaagggtg gcaatagcaa gagcattagc tacaagacca gctataatac
    39061 ttgctgatga accaactgga aacctagatt ctaaaacgtc tgatgaggtt atgagtatat
    39121 taaaatctat gtctaagaag tacagtcaaa ctctagttat gataactcat gatgacagta
    39181 tagcccaaat ggctgataga gttatattca tagaagatgg cagggtgtca aaggttggtg
    39241 ataaaaatga ttaatactac taaaatagca aaaagtaatt taaagcaaaa taaatcaaaa
    39301 agtattctaa taataattac tataatactt tcaaccttaa tgctttcttc tattggaatt
    39361 tatattgttg atgcaggagc atatcaaaaa gaaaatacta taaagtattc aggcaattat
    39421 caaggtatat tagcaaatgt agatgaaaaa caggctgata tattgagtaa tcatgcagat
    39481 gttgaattaa ctggtgaaat gaatggagta ggtgttgaaa aactggaaga tgattcaaat
    39541 atttctctag catacatgaa tgaagatgct ttgaaattaa atagttttga atttatcaaa
    39601 ggaaaattgc catcaaaaga gaatgaaatt gtgttagata gtggagcttt aaaggcactt
    39661 ggttataaaa ataaagattt aggtgaaaag ataaaaatat cttatgatga ctataaaaat
    39721 gataaaaaaa ttgaaaaaga gttcattata agtggaatct taaaaactag cgaaatatct
    39781 gaagcaggta aatattatta tgctattata tcagaatcat atatgagaaa tactagagat
    39841 atgtcacaag aagattttaa tatttatgtg aaatttaatg ataaaagtaa tttatcaata
    39901 gagcaagcaa aagaaaaatt agataaaatt gctaatgata taggactgga tactattaat
    39961 actgctgtaa atgaaaatta tataaatgct ttaaaaccag atatggaaac gattatgggt
    40021 ggagtttttg tagggttagt aattgtatta tctagtattt tagtaatata caatatattt
    40081 tatatttcaa tagttacaaa ggttcaagaa tttggaaaac ttagagcaat tggtgcaact
    40141 aagaaacaaa taaaaaatat agtgtttaaa gaagggttca tattagccgg aatagctata
    40201 ccaataggaa taattttagg ctatgtactt gcaaatatta taataaaatc atttatggat
    40261 atagatgtaa aatcatcacg attaccagtt atattatcgg ttgtggtaat aagctttata
    40321 tctgttgttt tatcactttt aaaaccaatg aaagtagcat caaaagtatc cattgttgac
    40381 gcagtaagat atacaggaaa taaaataagt aataagagta agagaaaagg atataaaaat
    40441 ataaatctaa agagattatc acatgccaat ttagaaagaa ataaaaaacg tacttacatg
    40501 acattggcat cacttatact tagtggaact atatttataa cagtatcaac tgccttagaa
    40561 agttttgatg ctgagaaaat ggcaagagaa cactttcctt atgatataga agttagacta
    40621 tctggttatg aaatgaacag tgataaaaat cctaaagata atttgaatat tttacaaatg
    40681 gataatcctc taagtaaaga tttttttaat caaataaaga acatggaagg aattaaaaga
    40741 atagaatctg caagaagtgt aaaaattggt atggaggact atgatgttga atttaagtat
    40801 gaccttttac aaagtataaa tgaaaatgat gtaaaatcat taaacaagaa tataatagat
    40861 ggaaaaataa atcttgaaag acttcaaact ggagatgaaa tagtaattac tcatgttgat
    40921 acagcaaaag aaatgggagt aaaagcagga gataaaataa gattaacttt atatgatgga
    40981 gataaaaaga taaaaaaaga atttaaagtt caagcaatag ctatgggggt tccaagtttt
    41041 ggtataggga aagattttat agatagaact ttgaaatacg attcaactag tagcttggga
    41101 atatatacag aagaaggaaa gtatcaagaa atcaaagata gtatcaagaa gattgctaaa
    41161 aataatggat ttttagagac tgattttata gatagtagaa ttgagtcaaa taaggctact
    41221 atttcattta taaagataat gggatacacg ctaacaggca taataggtgt gattggattt
    41281 atgaatcttg tcaacacaat gataactagc atagttacta gaaaaaaaga acttggtatg
    41341 cttcaagcta ttggtcttac taataaacaa ttagtgaaaa tgcttaattc agaggcaata
    41401 tattacactt ctggaatgat gataggaagt attctatttg gaggtatatt agggtatatt
    41461 gctgttatat ttctaaaaaa gactggatta tcttatgcaa catattcttt gccaatagta
    41521 ccaatcttgt tgatgattgt gtgtattctt atagctcaat ttataacaac ttatttgata
    41581 ggacgaagtt ttaataaaga atctcttatt gatagagtaa gatacagtga ataaaatgca
    41641 aatatttatg gttagtttaa ctagcaaaaa acatataaaa aaatatagtt aaagagattc
    41701 ataattaaat aggttaaagc atagtacaga gcaaacaatt taaacagatg tttgctctgt
    41761 attttattat gtaatcaata atatatctaa tatactgata ttattcatgt tagaaaatgt
    41821 accggtacaa ttctaaaaaa gtataaaatt gtaccatata aaatgaaaat tttgtataat
    41881 aatcgtatag aaaataaata ggagctgata tatatgaata agaagattaa ttatgcacca
    41941 ggaccaactg aaactaggga aaatgtaaga ttagcaagag cagaaaaaac aacaaatcca
    42001 gatatagata ttgattttgt tgaattttat aaaaagacat gcgagaagtt tggtaatata
    42061 attggaacaa aaaacgatgt ttacatattg agtggtgaag gaatattagg tcttgaagca
    42121 gcatgtgcat cacttacaga aaaaggagat agagtacttg taattgacaa tggtatatat
    42181 ggagaaggtt ttaaagattt tgtaacaatg tatggtgggg agtatgtgct tttttcaagt
    42241 gagtatacta aaagtataga tattgatgaa ttgaaagcat ttttagatga ggatagtaat
    42301 tttaaatatg caacagtagt gcattgtgat actccaactg gcgtattaaa tgatgtaagc
    42361 aaaatatgtc cattacttaa aaaatatgga atattaactg tagttgattc tgtagcaggt
    42421 atggtaggag aaagattaag tgtagatgaa tctaaaatag atataatatt aggtggttca
    42481 caaaaagcta tttctgcacc agcaggactt actatagtcg gaataagtca agatgcaaaa
    42541 aattgtataa aaaatagaaa aactgatgta ataggttttt attgtaattt aaatatatgg
    42601 gaaggctatt atgagaaaaa atacttccct tatacaatgc caataagtga cataatgggg
    42661 cttgataaag cacttgataa tatattagaa gaaggaatag aaaatgtatt aaatagacat
    42721 gaaaagatag cttatagtgt tagaaaatct attgaggaat atggtctaga actattttta
    42781 gaagaaggat attctaatac agtcacagct ataaaaattc ctgaaagtat aggagcttta
    42841 gaacttactg attatatgct taaaaattat aatacacttg ttgcaacatc actaaatcaa
    42901 tatatggata ctattttaag aataggtcat atgggagaga atgcaaatct aaataaaata
    42961 gaacatgtac taaatgtttt ggataaaagt ttaagtgcat taggattcaa aggaaatgga
    43021 aatttgttaa atttatttaa taagtattat ttttaataga tagggggata tagtatggaa
    43081 gttacagcta agcaaaaatt tacaacgaaa gacatggtgg aaacctcact attaatagca
    43141 ttagtattta ttgcaactaa atttataaac ataagattac caatatctat aaatggtggg
    43201 cttgtgcatt taggaactgc aatgttgttc atatcagcaa tagtatttgg aggtaaaaaa
    43261 ggtgctttat caggggctat tggtatgtca ctttttgatt tgatatctgg gtggacttta
    43321 tgggcaccgt ttacctttat agttagagga gttatgggtt atttacttgg aaagattgca
    43381 tgggcaaatg gtaataatgg gaataatttt ttaatcaatg taataggaat atgtgtttca
    43441 tcaatttgga tgctatttgg atattatgta acagaagtta tactttatgg taattttata
    43501 gtacctctta cttcaatacc aggtaattta atgcaagtat tgataggtct tataatagcg
    43561 cttcctattt ctaaggtatt gaaaaaatgt ataaaataaa tataaagtga actaaaattt
    43621 atgatagcat aaattatact gtataatatt aggatggagt acataattaa aaaattttag
    43681 tatagaggtt agttcacaat gttatcagtt acaagatatt caatcaaaaa tgttcgttta
    43741 aagccgtggg taaagtttat ttggtatttt gagacaaaat caaatatact gttaaataat
    43801 aagttacttc cgacagacag tatagatatt attctcaatc tttctgatgt tatggaatat
    43861 aaaattgaaa atcaagacta tactgctagt aatatgcatt ttaatggaat aagggataaa
    43921 catggattta ttattcaaca tggaaatata cgtgttatag ggatttcttt ttatccattt
    43981 ggtctctatc catttttaaa gataccaatt tcagagttta acagacaaat tgttgaccta
    44041 gaagcagtat cacagctatt tgcaaaaaaa ttggaagagt cattaaatcc aacacaatca
    44101 gtagaaaaaa ttgttttata tttagaagaa gtattattat ccatattaga agaagattta
    44161 atttcaaata aatatgtaaa gcttctaaat tcatttatat atgttaatag atatagcaat
    44221 ataaaagcat tttgtgatga tacaaatata aatattaaaa cattggaaag aatctgttta
    44281 aaatatacag ggtatacacc taagatttta aagagaattt acagatttaa aatggcaagc
    44341 aatcaactta tttataatta taaagatgat gaactttttg attttattta tgaaaatgag
    44401 tactatgacc aagcacactt tataaaagaa tttaaaaaat tttcagggac gtcaccaatt
    44461 aaatttattg gtgagaataa gacgattaaa gaaaatataa agtacagcta tttataatta
    44521 tactgtcgat tttttacaat acctccaatt tattttttga tatgatatag gaaaataaat
    44581 tggaggtttt acatatgaaa attattacag aaatagttga gtttaatgtg gaagaaaatt
    44641 tatcaaaaga agagtttata gaaattgtaa atgacttaga attaaaattt cattctattc
    44701 aatctggttt tattgatact gagcttttat atgatgaaaa gtctcaaaag tggattatga
    44761 tacaacattg ggaatctata gaagacctca agagtgcttc tagtaaaatg tttaaagatt
    44821 cttcaactga gaaatttaga aaagctttaa agaatcaaac tgttaagatg aatataatac
    44881 cacaaattaa aagttggaaa ttatagaact taatgtaaaa gatagttaaa tagtatcaaa
    44941 ctaaattagc caaataacat tttgtattta aattgttatt tggcttttag tgtttatttt
    45001 aatatgagtg ttatatacta gaaaaaccaa ccttaaatac tactatctaa aagcactatt
    45061 gctgtacgag aggcaatagg cattttagaa gaaggaggag ttgagctaaa gtatacatca
    45121 taatctctta agttttcttt ttttgtgttt cctccaaact ctaccatatc agtatttaat
    45181 atcgttttgt agtttgtatt ttgaaacttt gaaatatcaa ctgattgtat tagattaggg
    45241 tggaaattaa atataaataa atatttgccc ttactgtaca ccaaaatctt tttatcatta
    45301 tccatatgta taagttcatg actattttgg ataaaaatat cactgtattt tgtaagttcg
    45361 agcatagatt tatcaaaatt taataattgt ttatacttta agttgttatc ttctgaaagg
    45421 ctccattgtc ttctggcata cttatagctc caattgttgc cttctcgtgg aaaatcaatc
    45481 cactcaggat gtccaaattc atttcccata aaatttagat atccttcacc tgctagagaa
    45541 aaagttatta atttaattaa tttaataaga gatattgctc tattgataac atggttattt
    45601 gagtttattt ccatattcca gtacatttcc ttgtcagcta gccaaaaaat aattgtttta
    45661 tcgccaacta atgcttggtc atgggattca caatatccta tatttttttc tccaggtcgt
    45721 ctagtagtaa gttcatacca catttttccc aaatcccagt cttcatcaga taagttagag
    45781 atagttttta tccaaaaatc aggtactccc attgcgagtc tatagtcaaa tccaattccg
    45841 ccgtctttta tagggataca cataccaggc attccactca tatcttctgc aatacttatc
    45901 gaattaggtt taatttcttt tattaattca tttgcaaatt ggagatatgt tatagcttca
    45961 atatctgtat tcatactaaa atatttttca taactatcaa atgaaactcc aagaccatgg
    46021 ttatgatata acattgaagt cacaccatca aacctaaagc catcaaaatg gtactcattt
    46081 aaccaaaatt ttatatttga aagcaaaaaa tgtattactt caggtttacc atagttaaaa
    46141 agttttgtac cccaagcagg atgatttccc tttgaacctg agtggaaaaa ttgatgttca
    46201 cttccatcaa actcatttat tccttctaaa gtattcttta cagcatgaga atgaactaaa
    46261 tccaataaaa cagcaatccc cattgaatga gcagtgttta tgaggttttt taagtcttca
    46321 ggagtaccaa acctagatga gattgcataa aagtttgaaa cttggtatcc aaaagatgca
    46381 taatatggat gttccataat agccataagc tgaatggtat tgtatccagc tttttttatc
    46441 ttaggaagta ttttttcagt aaattcatta taagttccaa tagattcgct ttcagtagac
    46501 atacctatat gacattcata gattagtgga taagttatgt tttttaagtc aaaatcattg
    46561 tcagtccaga taaatggagt ttttggttgc catatttgtc cattaaatcc accaaaatct
    46621 ttttgaatta ctctttttat atataatggt atacggtcaa atgtttttcc atttgcagta
    46681 acttgtacct ttacctctga tttgtgaggt aagctatttt gaccaggaat aaatatttcc
    46741 caattaccag acccaatttt tcttagagga tgagattttc tattccaatt attaaagtca
    46801 ccaattagtg acaaactatc tgcatttgga gcccattccc tatagaagaa tccatcattt
    46861 gtctgatgaa atccatagta aagatgagca tttgcaaaag aactaaaatc tttatagttt
    46921 ttcaatgttt ttgatttcat attctcataa tgtttcattc gcttttttat atcagattca
    46981 aatggttgta ggtatacatc aatatctaaa attttaaatc ttttttgact tttcattgta
    47041 tttctcctcc ataataaata ttacatctaa aaaataatat ttatctcata ctatcttctc
    47101 tatataattg atatatatta tataatccta ataaaaagct taagccacca atgattaatt
    47161 tcataattta cctccctagt atttatactt atatatcgta ttcatcaaaa tttaaaagtt
    47221 tgtttaaaac tcttttaata atatcataat caaagccttt ataggaaaga tgttgagaaa
    47281 ttttttgata tattttcttt ttatcttctt tctttactct ttcatacctt ttttttgcta
    47341 gatacatagc attttcaaat tcagtgtcct tgtctaattc agatactgct tcattgattg
    47401 tacttctatt gataccttta ttatataaat tctgcttaat tctgtttttg ccacatttat
    47461 ttaggttaac atttgtgtta acaatttttt gagctaatac actgtcattt acgagattat
    47521 aacttttaag aaaatctatg accctctcaa ttatattttc atcaaattct gatgatagtt
    47581 tttcttttaa ttttttttca gattggtcag catgagataa aatatttaat gctttatttt
    47641 tagcttttat atacatttca tcatctaaaa taggttttaa ttcttcttca tttatttcat
    47701 tccccttttt taaattaaat gtataaacaa gttctttaaa tatagcaata aaaaatttat
    47761 catctacata aatattaact ctatcatcat ttcttttttg ttgttctatt tttgtaatta
    47821 tacccataag tcctcctttt ttatatgtaa ttatattaac aaaagcaact aataaaattt
    47881 aacaaaaaac ttatatttgt atgttatatt ttatcaaaat taagacaaaa tagtaaaaag
    47941 ttatttttat taaaaagtaa agtagaatca tgttaaataa ttattttttt aagtgttttt
    48001 tagcatataa atataattat atacccaaaa aaacaaatta taagctttaa gaaataaaaa
    48061 ataatggtac aatagtatta taacattaaa aggagacaaa atatgagaag tgaaaatcta
    48121 gttaagatgg cagagttgaa aaatactgaa aaactagaga aatttaatcg ccataaaggc
    48181 aaaatcaaaa taggtatatt gggaggtact tttgacccta tacactatgc tcatttagca
    48241 acagcagaat ttattagaga caagtatgac attgacaaaa taatctttat accatcagga
    48301 aatccaccac ataaattatg tatcactaca gataagtatg atagatataa tatgacactt
    48361 ctagcaactg aaagcaacga agatttttta gtttcaaaag tagaaatcga aagaaagaaa
    48421 aggacttata caatagatac attaaaatac ttaaagaaaa aatacaaaaa tgcagacatt
    48481 tattttataa caggtgcaga tgcaatttgt agtgttgaag agtggaaaga tgtaaagaaa
    48541 aactttgagt tagctacttt tatagccgca actagaccag gaattagttt gttaaggtca
    48601 caagagacta tagaaaaact aactaagaag tataatgctg acattataac agtttatgtt
    48661 ccatcactgg atatatcgtc cacatatata agggaacagc taaatgaagg caagtcaata
    48721 cgttacttag tacccgaaaa tgtagaaaat tatttatatg aaaataaact atatcaatat
    48781 ggagatgatt aaatgaactt agaaaatatt aaccaaagac taaatcaaat gctaccagtg
    48841 gggaggctta gccattcaaa aaatgttgca aaatgtgctg aaaaattatg tgagatttat
    48901 ggatgtgaca aagaaaaagc ttacttagca ggaatgattc atgattgtgc aaagtattta
    48961 agtgacaagg aaatagagga ttatgtaaat aagtatgaaa tatatttaga cccaatagag
    49021 gatggaaatc gttccttgtc tcatagcgta attggggcgt acatatgcga gtatgaattt
    49081 gaagtagaag atgaagatat tataaatgca atcaaatatc atacaacagg gagagaggac
    49141 atgtctcttt tagaaaaaat aatttacata gctgatttaa ttgaagaagg aagaaaattc
    49201 ccagttgtag atacattaag agaattagca tatggaggga agcttgatga agcactttta
    49261 acttctttta ataatacttt aatgtttgtc atcaataaaa aagaagagat acatccaaga
    49321 acagttatgg caagaaacta tctaattaaa gaaaagttat tataaaaaag ctatataaag
    49381 gcaaacatat taataaattt aaatttgact atgttacaaa atcgtattaa tatgttacaa
    49441 taactaagtg tattttaatt aggaaagtga ggaattttta tatgacagtg gaacaaatga
    49501 caaaaatagc atatgatgcc atagaagata aactaggtca agatacagtt ataataaata
    49561 taggaaaagt ttctagtttg tgtgattatt ttattattac tacagcatct tctcagagac
    49621 aggtaaaagc tattgctgac aatgtggaag atgaattagc aaaactagga ttagagccaa
    49681 gaggtaaaga aggacaagga actcaaactt gggtactcct tgattatgga gacataatgg
    49741 ttcatgtatt taatgaggaa aatagagggt tttataattt agaaaaatta tggaaagatg
    49801 caccttatat agatattgac acattagcat aaacatgata atatatgtta ttataattag
    49861 aaaatttcaa aaattatatt aaattgaata gactagagca gtaaaagatt atattttttc
    49921 agagagttag tggaaggtga gaactaatat tatataactt tgaacttact agattaaaat
    49981 ctattctcca tggctggatt aaaagctatc taagagagtc tatatatgta gtaggctaat
    50041 tagggtggta ccgcgaagat ttatcctcgt ccctaaacgt aagtttagtg acgaggattt
    50101 tttattttca aagaattatt tggaaattat aagtaaataa tactaaataa ggtagttata
    50161 cacaattaaa aataggaggc aaaatatgag cgtatataat tttaaagaag tagaatcgaa
    50221 atggcaaaaa atctggaaag ataataatca gtataaaatg gatactgcac aaactgaaaa
    50281 acctaattat tacacattag aaatgttccc ttatccatct ggaaaaatac acatgggaca
    50341 tgttagaaat tattctatag gtgatgttgt cgcaagattc aaaaaaatgg aaggatataa
    50401 tgtacttcat ccaatgggat gggattcttt tggattacca gctgaaaatg cagctataaa
    50461 acatggaata catccgcata aatggacaat ggaaaatata gaagaaatga aagagcaatt
    50521 aaatttatta gggattagtt atgattggga taaagaagtt gcaacttcaa ctccagaata
    50581 ctatagattt acacaagaaa tatttttgaa gtttttagag catgggcttg catataagaa
    50641 aaaatcatat gttaactggt gtccttcttg tgagactgtt cttgcaaatg agcaagttgt
    50701 tcaaggagca tgtgagagat gtaaagcaac agtattaaag aaagatttag aacaatggta
    50761 ttttaagact actgagtttg cagaagaatt acttaatgac ttagatacat tagatggatg
    50821 gccagaaaaa gttaaaacaa tgcaaaaaaa ttggataggt aaaagtacag gagcagattt
    50881 agtttttgat atagatggaa ctgataaatc tatgacagta tttacaacta gaccagacac
    50941 aacttatgga gttacttata tggtacttgc tccagagcat gaattagtta aagaattggt
    51001 tgcagggact gaatatgaag cagatgttga agcttttgtt caaaaaatgc atactatgac
    51061 agaaatagaa agaacagcag ctgatgtaga aaaagaagga atgtttatag gtagatatgt
    51121 tataaaccct ttaaatggca agaaagttcc tctatggata gctaactatg tattagttga
    51181 gtatggaacg ggtgctataa tggcagttcc agcacatgat gaaagagata gagattttgc
    51241 tgaaaaatat aatttagaca taattgatgt aataacagaa gataacaaaa tgataaattc
    51301 agaagaattt aatggattag atgcttcaga aggatttgaa ggaataatcg ataagttaga
    51361 aaaagaaggt agaggaaaga gaacaattaa ttatagactt agagactggt tagtttcaag
    51421 acaaagatac tggggttgtc ctatacctgt ggtttattgt gatgaatgtg gaatagttcc
    51481 agttaaaaag gaagatttac cagttctttt accaacagat gttgaattta ctggaaaagg
    51541 ggaatctcca cttacgactt caaagcaatt tatgtcaaca acttgtcctc actgtggaaa
    51601 accagctaga agggaagttg atactatgga tacatttgtt gattcttctt ggtatttctt
    51661 aagatatgtg gatagcaata atgaaaatga accatttagt aaggaattag ttaatagatg
    51721 gcatccagta gaccaatata taggtggagt agaacatgct ataatgcatt tactttatgc
    51781 aagatggttt gtaaaggcat ttaagagtat gggaatggta gacttcaatg agccatttaa
    51841 aaacttactt actcaaggaa tggtacttat ggatggttct aaaatgagta agtctaaagg
    51901 gaatacagta tctcctatgg atataataga tgagtatgga gcagatactg caagactttt
    51961 cgtattattt gcagcaccac cagaaagaga tttggactgg tcagagcaag gtgttgatgg
    52021 atgctttaga ttcttaaata gggtttatag attggttgac gagttagcag atgtggttaa
    52081 aaaggatgta gagtttggag aattaaattc ccaagataag gatatgagat atactataca
    52141 ctctacactt aaaaaagtta ctgctgattt aagtgaaaaa ttcggattta atactgctat
    52201 atcagctctt atggaattaa taaatgatat gtataaatat aaagagttag ataatataaa
    52261 cgaagcagtt ataaaagaag gtgtacaaac tatagtaact ataattgcac catttgcccc
    52321 tcatttaggt gaagaactat ggactatgat aggtaaagaa ggaagtgtat ttgatataga
    52381 ctggcctaaa tatgacgaaa aagctttagt aaaagatgaa atagaagttg ttgtacaagt
    52441 taatggaaaa gttagaggaa aattaactgt taactcaaat atatctaaag atgagatgga
    52501 aaaggtagct ttagaagatg aaaaaataaa aggattagtt gaaggtaaaa ctatagttaa
    52561 agttgtagct gtacctaaaa aattagtaaa tatagttgtt aaataactca aaaatatgaa
    52621 caaaaatata aatttataaa ataaatgagg ctgtctcaaa atagagataa gccttttttc
    52681 attgttgaaa ttataaaaat agatttgatt ttatacaaaa aaatgattaa agaactaaaa
    52741 agttcattct tatataccct agttgttgtt ttaaatatta ttataattaa tgttaaatcg
    52801 agttaatgta ttaagtggta tgtaaatcat tcagtttcca aagtgttgtt cgtcaaggaa
    52861 ctgctctaag cttaaacgaa aaaaatataa ttattgtatt ttgaaatttt tttctatata
    52921 atgaaaacag gcaaaaaagg tgcatatcta tgctttatat gaaacaccca gacaacgaaa
    52981 ttcagattca tataatagct accatgtttc taaaaaggaa cttgtaaaaa agatagcgtt
    53041 tcaacttccc agttgattaa aattatcagc aggaaaacaa gtatggtcag cagtggtatt
    53101 ctaatgggtg ttgtcgatat atccaagttg ggattgtctg aggatgttat caaataactt
    53161 gtgataggtg cagtagatgt ggagattcct gatacggatt tattctcagg ggatggttgc
    53221 ttcgggagat atggagcgta accagtttat tgatatggta accatttttt gtctaatttg
    53281 atgaaagaat cccaagaata ccatacagaa gtaagacagg aattaactgg tggtataaac
    53341 tgataaaggc aaatttaaaa attttgatag gatgatttta agatttatct tctattttgt
    53401 tttttagaaa taattgaaat gttatgagga ggtatgtaca aatggagact gtaacaaata
    53461 atcaatcagg tgtagaaatt caactcagtc tgtttgaagc tatcaaagat ttattgttaa
    53521 ttaatcctat tttcttgttg ggaattatct tgattggtat tttcttagtt gtaatattca
    53581 agaaaaatag tgatattcca aaggtcaaaa catctatttt atcactggca atgtattact
    53641 acttatgttt aacactatcg catattgttg gtatacctac attcggtgaa tatataagac
    53701 tgtcacagtt aggggaaacg ttctttaatc caaacataaa tcttattcct tttagtgatg
    53761 gatttagttt gagttttatt ttgaatattt tactttttgt cccattaggt tttttatgtc
    53821 cgcttataag caaaaccttt gaacgtttga gaaatacatt cttgattggt tttggattat
    53881 ctctttttat cgaaactatt cagcttttta cgttacacag agcaaccgat atagacgact
    53941 tactcacgaa cgtaattgga acaataatag gctatttctg cttcaaactg attgctaaat
    54001 tgcgaattgt aaaactacat tcagatgatg actctatgga acaggattac acagtatgta
    54061 ttccgattgc cattataata gttgccctta tattaggatt ttttagttaa gttccaaata
    54121 gctaatttgg gaatccagac aatataacag atactatgtt accttttaca ggagcatact
    54181 atctgttata ttgtcaacat cctattttat ggtttgtgtg tagtttcctg taaactgaac
    54241 taaataatta aatagaagct attagaatta ataataacag atagatatta ataagcataa
    54301 acaaatagta aaatgtgtag atatagacgt ttttaagtga aactattata aaataattga
    54361 ctgataatca actgacaaaa cctatttttt taggtttaac tgacatttaa ctgacagtca
    54421 gtttttacta tttaaataga agttcgctta gattgtcgga agcttctttg tccatttctt
    54481 taagtacatg agaatatcta ttcatagtta tttttatatc tgtatgaccc aatctttcag
    54541 aaacaacttt catattagtt ccccctaaaa gcagcagagt ggcacttgta tatcttaaat
    54601 catgtattct aatctttttt aaattatttt ttttgtaaaa ttgtgaaacg tttttcttag
    54661 tgaagaaggt agaaacggat ttaaattggt gtttagacaa actaagttat ttctgttttc
    54721 caggatacct tacaatttta atttgctttg tcttagtttt tcaattttca atttttcaat
    54781 taattctttt ggagctgata aagctctttt tgattttggt gtttttggct ctttaaaaga
    54841 tattttgcca ttagaataga caagaatttg attaacattt atcagattgt tatctaagtc
    54901 aacatctgac cacctaagcc caatagcttc tcacattctt aaacctagaa gtaacattaa
    54961 aagaataggt atttctatat tattaccaag taacttttct attagcaata atacttcttc
    55021 tctattgtat atttcatttg tagaatattt ttctttagaa ggaagtttta taaaatcaca
    55081 tgaattttct tgtatttctc ttaatctata cgcttccctt attacagaac ttagaaagct
    55141 ataccttact ttagcactag taaaggtaga attattaaag ttataattta caaaagcttg
    55201 tactgaacta ggatttactt ctgtgagttt tagattctta aaaaaggttc tatgtaattt
    55261 ttaacccaag attttgtatt tgtaacagta tatggagacc aattattttt attcatgtct
    55321 atatatttat aacatctttc tacaaatgtc ataccttttg gagcaacaaa cttattatta
    55381 tttatagtag actttatttc aattaaatgt ttttcagcat cctttttctt tttatagctt
    55441 ccataacttt tttgtttctt tttgccagtt tcttattcca catatacata gaatttttcc
    55501 catctttttc ttataaaagc tgatttgata ttcatatatg tacgctccct ttataagtta
    55561 gttttataaa agaacagttg gactgctcta attatgtcat tatcttttta attctttaca
    55621 gttacattat aacacgtatt tgtatacact taaattaaca ggaagataaa tatcgttaaa
    55681 ggaggaaaag aaaatttaat gtagaattat gtaagatata tagtatttca tatataaaag
    55741 ggggagatat tgtgaaatta aagaaattat tatcactagg gttagccgtg tcaatgtttg
    55801 ctgctggtcc tatatcagct aatgcacttg atacaattta tactattcaa ggaaaagata
    55861 aatatgaaac ggctgctctt atagctgatg aacaaaatta tactacagct atattaatta
    55921 atgcagacag cacaatggct gatggattaa gtgcgagtgg acttgcagga gcaacaaatg
    55981 caccaatttt tttaactaag aaaaataaca tacctaatgc aactcttaaa agagtagaga
    56041 aagctaaaaa ggtatacata ataggtggag aaagttctat tgataaagca acagaaactc
    56101 ttctaaaaga taaaggaata gaggctaaaa gacttcaagg tagtgataga attaagacaa
    56161 gctataatgt tgcaaaagaa ataaactcaa ttaacaaagt aaataaagtt atattgacta
    56221 atgcttttaa aggagagcct gatgcaatga gtgctgcacc tgtagcagtt agagataaag
    56281 cagctatagt attaactgat ggaaaaagtg ttccatttaa tacaactggt gtagaaagtt
    56341 atgtaatagg tggtacttca tcaatgagtg acaaactagt taatgatact aattcaacta
    56401 gattaggtgg agtagataga tatgatacta ataaaaaaat agtaaataag ttctataatg
    56461 gcgcaaaaga attttatata gctagtggta ctgatttagt ttatgcttta gttgcttcac
    56521 caatggctaa aaataatcct attgtactag ttgatattgg aagtaataaa gatatactta
    56581 aaaatgctgc aaaagtgact gggataggaa atctaagtga taaaattatg ctagagtgtg
    56641 aaaataccat caataatatt agtcttccgt cttcaaataa aaatataata tgtggattaa
    56701 agattgattt tgattcaaag cacataattt ggcaagataa aggaagttat cttgaatgtt
    56761 atgatgataa ccttgaatat tatactgaaa aatataaaga cccaacagtt cctataaata
    56821 tagaaaatac aagtacacaa aatttagatg taacaaaatt aaaagtttat ggagaagcta
    56881 attcaacatt atatatgggg caatatgcta aaataaaaat ggattttaat agtttcggtg
    56941 tattaaagcc aggagaaaaa tgtactattt atttagatat aatttcatta gatccatcaa
    57001 gaagcatgac attaacattt tcttatgtag gtgataaaga aaattataaa tatgaacaag
    57061 gattggcaag tagaatatta ttttataacc cagatggaga agattttttt gaatataaat
    57121 aactagtggg tatgtaaatt aataagggtt ttataagttt aattttttta ttttcgtttt
    57181 atattaacta tgtggtatgt aaatgtctcg atattgctca tatgttgagt tattatattt
    57241 agtttcatat gaactatatg gattttaaaa ttaaaaatac ttaaaaacat ttactttaat
    57301 agtaggtgtt tttttgatta aaagaatatt attataatgt aaaaagtaat aaataggtaa
    57361 aatatgtaag aattatatgt tataatattt ttagcaagaa gatgtaatct acaatttata
    57421 gagtggagtt catgtatcaa aaaattatcc tcccgacgct aagaagggag gtgaatatac
    57481 atggataatt ttttacaagg catactagca agtctatctg ctagcttaat agtttatata
    57541 gctagcaaac tatttagaaa gcgtaaaaaa ccactcaaag cggcaactaa gagtggttgg
    57601 gaatttgatt taaaaatcag attccataaa actaagtaat ttctaaatta tgaactccac
    57661 tctacagcaa aatagattgt agttcttctt gcttttatta tatcacaaat tggtacagat
    57721 attcaaaaat aatattttta tgatataata aagtcataga aattttgcag tgttcgattt
    57781 tttgaagaaa ttaaggctta acagttgaaa tataaggcat tgaggacttg tgataagtgt
    57841 tatcaattgc actactcatg gttcactgca aatttgagag atttgtatat gtgtaggcat
    57901 tggaaatact caatttattt tggggtttta tattaactat atggaatgta aatatttttt
    57961 ttatatataa acttctaaac ttttacaaaa gttttatatt aactatatgg aatgtaaata
    58021 cacttccaac aagcattgta gggttgaagt ctacaggttt tatattaact atatggaatg
    58081 taaattaaat cgtatttata attatatcta cacttagtaa atgttttata ttaactatat
    58141 ggaatgtaaa tccaatagac cctccaataa ctccagatat tccttctggt tttatattaa
    58201 ctatatggaa tgtaaataat gaactatcta aaccaaggtc ataatttaat tgagttttat
    58261 attaactata tggaatgtaa attgtatcca aaaaattaca ataatcatac gaattgctaa
    58321 tataagcagt caatatatgt gtacatttat ccattttatc tctaaacata taaattatta
    58381 tccccctaaa aaactttcat aaaaacaaaa agaacaatat ctctttggca actggctaac
    58441 ataactcata agatatttat ataagtctta gtccctatag ctttgcgtca ctagatttct
    58501 ctagttttgc cgatttagtt ttattctata actaaataat acaatagaat tagttattat
    58561 tcaacaagat tgtttgaaaa ttgaataaat ttataggtat gaacgtaatt tcacacttaa
    58621 aaacagacta aatacgtaga atatatagaa aaatttacct gtagtttttg tgataaaaag
    58681 ctcctattat taatttaagc tagataagtt tgaggaagtg acataaattg aaagaaggaa
    58741 tatattatgt tgaataaaaa attaccagat gcagaattaa aaattatgaa atacatatgg
    58801 aatactggtt ataaaactgt aatatcaaaa gatgttgcag attaaataga aaaaacatat
    58861 gcttggaagc atacaactac aattacactt ttagctagat taactaaaaa aggttttttc
    58921 atatcgcaga gaattgggaa acatgtacac tatagagtat taataaaaga gaaagaatat
    58981 ctcaaaatag agggaaaaag aatttttgga ggtctacata acaatccatt atcagaacta
    59041 atttcaaaat tacatgatgg agaagaaata actgaagaaa aaataataga aataggaaat
    59101 tggataaaaa gctggaaaga tgaagattaa taaataaaag gtagctacta atataagtgc
    59161 tacctttttt cttgtggata atattgggga taagttgtgg aaaatttgtg taaaaattgt
    59221 ggataaaata ttttgctgac atttaactga cataagtatt agattttgat ttaaaaatgt
    59281 tgaaatatca ataaataatt aaatagaagt tattagaatt aacaatagat tcctttttca
    59341 aagaagtctt tgatttcatc aaggttatca gtttttccaa gtgctaagat aagttttatt
    59401 ctagcttttt gacctggtaa gtccccacca aatatacaac caagattttt taaatctcta
    59461 ccagaaccaa agtaaccata actatcgaat actctacctg aatgacatct agaaactata
    59521 actacaggaa gtcctttttc tctagcatat tcaactccag aaagcatttg aggaggaata
    59581 ttacctctgc ccattgcctc aataactata cctttataac cactatcaac agcaaatctt
    59641 ataaagtcag cattttctcc tacatatgct ttaaataagg caactttaga ttctacctta
    59701 tcagtatcta taattgttct atttacaata tctcttgtaa ggacaagttc gttgcagtca
    59761 attattccta atgggccact agttagagat ttaaatgtat ttagagaaag agtatttgtt
    59821 ttagtagctt cagaagctaa taatacttca ttgtttaaaa ctacaaggac tccttttccc
    59881 atagcatctt tggatactgc agtacaaact gatgcagata aattacttga accatcatat
    59941 ccaagttcag aactacttct catagcacct gtgactatta caggtttgat gttgtcaatt
    60001 gtaaggtcta gaaaataagc tgtttcctct aaactatctg taccatgtgt tattacaaca
    60061 cctgtaatat cttttcttgc taataaatca tttacataat ttttcaattc catcattcta
    60121 taaggtgtta tgtgaggtcc tggaatttca tcaaaattaa aaacttcaac atctgcaact
    60181 ttatcaatgt tggtaaccat tgatagtatt tgttcacctg ataaagttgg tatagctgct
    60241 ccgactttat catctactgt catagatata gttccaccag taaaaactat ggcaactttt
    60301 ttcttaatac tcatactatt ctctgccttt cataaataaa atttataatt ccgataggat
    60361 tatatcaaaa aaagtagtta aggtctacat aaactctttt attcatataa tttagatatt
    60421 tcagtgtaat ataattattt cttaattttt tgccattcaa cgatataacc atttaatatc
    60481 tctcttatgg cttttcctat cttagtataa gcttcatcat atagatttgc tagagatatt
    60541 ctaattgacc attcagggcc atagaatcca tttccactaa gtaaaactac tgaatagtca
    60601 ttagctaatt tataaagaac atctactgga gatgcagttt tacttataaa tttaaataag
    60661 tcttctccgt agtttaattt agcccattct tcaatatcaa attgagtgta atatgcagca
    60721 ttgtttttgt tttcattaat tggaagctct aaagcttcaa ataatagttt ttgacgtcta
    60781 tggcagatac tcatattaag ttttttgtag gcatctactt tgtcaatcaa tgcaaaagca
    60841 gagaaaaacg ccatttgtac ttgctgtgga gtagaaagac cagcagtatg gttgagagca
    60901 acaagtctgc tatcagcaac aactctttcc ataaaggaaa gactagaagg gttaagactc
    60961 atatcactgt aacgcttatc tactgatttt tttaattctc cagttaaatc atttattttc
    61021 ttatcaaaaa catttttctt atgaagggca aatgtaccaa gtctccatcc tgtaactcca
    61081 aaatattttg aataagaata tactccaaca gtgttgtaag gtagttttga cattaaggat
    61141 gaaaaatctt ctacaaaagt tccatataca tcatctgata ttatcattaa atctttatta
    61201 taattttcaa ttacatctat tagattatta caagatgttt catccatagc tatagaagca
    61261 ggattattag gattaacaac gaataaagct ttaatagatt tgtcacgaag tttctctaat
    61321 tctttttttg tatattgcca tgtatgagca cctttttcat caacttcatt agcatttata
    61381 tttaccactt taaagtcgta acgaggaagg ttaggtattt caagataagg tgtaaatatt
    61441 ggagtcatta aggctatggt atctcctttt tttagaagtt catttgccat taatgaatca
    61501 aatatatagc acatagcagc tgtagcacct tcaacagcaa aaatttctac atcaccatat
    61561 ttacctgata tatcatattt catttcttga actaggtaat cgtgtactat tttttccata
    61621 tgaggtaaca ttctatctgg aagtggatag ttatcaccaa taattccatc agctagttca
    61681 tgaacaaatt catctccatc aaatccaagt tcatttatac caaagtttat aatatctcta
    61741 gctaaatatg ctccaggcat atctatattt tcatttataa atttaaaaaa tctttcttta
    61801 ataccctttt tttgaggcat tccagccaaa tgacctaaat cccaattaga acgagtttca
    61861 gtaatagcga aatgaccaaa agtaaaaaag gcttctctag cagttgaaca agtccagttt
    61921 ggatttccac gacctgcatc aagtaattct ctgttatttt cttttgcagt gtattttgca
    61981 atatctatta atttgtcctt aaattcaaaa gggcttattt ttccatatat gtttttgatt
    62041 tctttataag tatgattttt cat
//
LOCUS       DAEPKC010000010        60132 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.010, whole genome shotgun sequence.
ACCESSION   DAEPKC010000010 DAEPKC010000000
VERSION     DAEPKC010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 60132)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 60132)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..60132
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.010"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(33..1313)
                     /locus_tag="KR294_000726"
     CDS             complement(33..1313)
                     /locus_tag="KR294_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HBH0238839.1"
                     /translation="MNILGLIVEYNPFHNGHIYHLSKSIEKTNATHTVAIMSGNFLQR
                     GEPALFDKYTRAKIAVENGVDLVIELPTLFACQSAEIFSHGAITILNSLNCINSICFG
                     SEEGNTEILYNIAEILANEPNEFKLLLKKYLDDGLLFPTARANALFDYIHQDKKNNFI
                     QNYSKEQLSKTLNSSNNILGIEYIKNLIHLNSSIKPFTISRVQSEYNSEEIESDICSA
                     TAIRTSLKENTDLFHLKNVIPEKTYNILNEKIDNGFLPMFDDFFFDILKTIILRDMDT
                     LKEYFEVNEGIENRIYKDIFTSEFLHELQLAIKSKRYTLTKIKRTLNNILLGIKKSDM
                     QLIKNIDTIPYIRILAFNDKGREILKEIKNKSEIKIINKFSNISFSLDDTIFKTLISY
                     DIKATNIYNSIYYKNNKDLVKGPMDFYTHPIYVK"
     gene            1776..2972
                     /locus_tag="KR294_000727"
     CDS             1776..2972
                     /locus_tag="KR294_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HBH0238840.1"
                     /translation="MKILVLNCGSSSLKYQLIDMNNEEVLCIGLVERIGIEGSILKHE
                     KAGRDDKYVVEQPMKDHKDAIALVLEAVAHPEFGAVKEMKEIDAVGHRVVHAGEKFAT
                     SVVITPEVEEALKECIDLAPLHNPANIMGIDACKAILPDVPMVGVFDTAFHQTMPKSS
                     YLYGLPHELYTKYGVRRYGFHGTSHNYVSQRAAEILGKDIKDLKIVTCHLGNGASIAA
                     VDGGKCVDTSMGFTPLEGLIMGTRCGDIDPAILPFLMRKEGLDADGLDKLMNKESGVY
                     GMTGISSDFRDIEDAAKNGDERAQATLEAYVKKVQKYIGAYAAEMNGLDVVVFTAGVG
                     ENGKAIRADIASNMEFLGMKLDKEANDVRGKETVISTADSKVKMLLIPTNEELMIARD
                     TLRLVK"
     gene            3065..3589
                     /locus_tag="KR294_000728"
     CDS             3065..3589
                     /locus_tag="KR294_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HBH0238841.1"
                     /translation="MKVSIEKINRKETDKIDLNFCEKIDTISYCDEIYKLVSPVNLKG
                     KVSKTNKGLYLDIDVNFTIVDNCSRCLKEVEIPLEYSIQGFLVKEEDYDEDEFEEFDP
                     FIFDGEEIDLIDIIEQTLDFNVPHKVLCSENCKGLCQVCGANLNEEECSCSEITNDEE
                     YIDPRFAKLKDLFN"
     gene            3614..3790
                     /gene="rpmF"
                     /locus_tag="KR294_000729"
     CDS             3614..3790
                     /gene="rpmF"
                     /locus_tag="KR294_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HBH0238842.1"
                     /translation="MAVPKRKTSKSNTKMRRAANSKMEATGFVSCPQCHEPKLPHRVC
                     PDCGYYKGKEVVSK"
     gene            3997..4554
                     /gene="fapR"
                     /locus_tag="KR294_000730"
     CDS             3997..4554
                     /gene="fapR"
                     /locus_tag="KR294_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription factor FapR"
                     /protein_id="HBH0238843.1"
                     /translation="MKKKSKAQRQKELIDMLKTDPFYTDEELSSLFDVSIQTIRLDRM
                     SLNIPELRERVKSIAETQSSKVKTLGVKEITGEIIDLSVGRLGISMLEVTQDMIYSKT
                     NTLKDTYIFSLADSLAMAIIDAPKVIMRVANVKSFKLIEQQDRLIAKAEVYRNIDKKH
                     YVKVVINNKAQEQIFRGKFIFEELD"
     gene            4565..5587
                     /gene="plsX"
                     /locus_tag="KR294_000731"
     CDS             4565..5587
                     /gene="plsX"
                     /locus_tag="KR294_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HBH0238844.1"
                     /translation="MKIVIDGMGGDNAPKSNVEGAVNAIKEYQVDLIITGDKDLLEKE
                     FSNYEFDRNKLEIVHTTEIIENEDKPVKAIRSKKDSSMVVALNLVKEGKADAIISAGN
                     TGALLAGGLFVVGRIKGIDRPCLCSAIPNVKRGMTLIADCGANADCKPKNLVEFAAMS
                     NIYSRKVLGLENPKVALANVGLEEGKGNDLVKRSYEEIKKLDLNFIGNVEAREVINAY
                     TDIIICDGFTGNILLKSAEGVALSVMSLIKETFMASTKSKIGALLIKDDLRKLKSFID
                     YSEYGGAPLLGLNGGVIKAHGSSDAKAIKNAINQGIKFSKGKVVEDINQFISKYNEEN
                     KNNEDE"
     gene            5613..6599
                     /locus_tag="KR294_000732"
     CDS             5613..6599
                     /locus_tag="KR294_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HBH0238845.1"
                     /translation="MNTKAGILGVGSYLPEQSYDNFHFEKIMDTSDEWISTRTGIKER
                     RFAKESEATSDLASKAALKAIECAKLNVEDIELIILATITPDMSLPSTACIVQDAIGA
                     VNATAFDISAACSGFVYGVTIAKQFVETGCYKNVLVIGAETCSKFLNYDDRTTAVLFG
                     DGAGAAVIGPVNEGGILSTHMGSDGKGKDCLKVPAGGSRLKASKETVEANLHTIEMAG
                     SDVFKFAVRKMAETSLRALEKANLNTTDIDYLVPHQANIRIIQASSKRLELDMKKVYV
                     NIDKYGNMSAASIPVALDEAYREGKIKKGDNVVLVGFGGGLTWGASVVKWTL"
     gene            6708..7637
                     /gene="fabK"
                     /locus_tag="KR294_000733"
     CDS             6708..7637
                     /gene="fabK"
                     /locus_tag="KR294_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HBH0238846.1"
                     /translation="MNKICKILNIKYPVIQGGMAWVATASLASAVSNAGGLGIIAAGN
                     APKEAIKKEIVECKKLTDKPFGVNVMLMSPFVDDIIDLIIEEKVQVITTGAGNPAKYM
                     DRLKEAGTKVIPVVPTIALAQRMEKLGATAVIAEGTEGGGHIGELTTMVLVPQVADAV
                     NIPVIAAGGIVDGRGIAASFALGASAVQVGTRFICSEECSVHSNYKNLVLKAKDRDAI
                     VTGRSTGHPVRTLKNKLSKEFLKMEQNGATPEELDKKGTGALRFATVDGDIEKGSFMA
                     GQSAAMVKEITPCKEIIEAMVNQAREIMPAIEL"
     gene            7653..8603
                     /gene="fabD"
                     /locus_tag="KR294_000734"
     CDS             7653..8603
                     /gene="fabD"
                     /locus_tag="KR294_000734"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HBH0238847.1"
                     /translation="MGKVALVFPGQGAQYVGMAKDLYENNTVAKSVIDEASDALNMDL
                     KNLMFNGNEEELSKTENTQPAMVTHSVAVLKAVQAQVDLKYSACLGLSLGEYSALVAA
                     DAIDFKDAVCLVKKRGKFMQDTVPTGVGAMAAILGLDRSILENVVKDIQGGIVEVANY
                     NSPGQIVISGENEKIEEAMVKCKEAGAKRAVKLNVSGPFHSSMLREAGVKLASELEKV
                     NITKPKVDVVANVNADYYKNEGKDLLIKQVSSSVLWEDSIERLLNDGYDTFIEMGPGK
                     TLKAFIKKIASNKKANVNIYNIDGIDSLNEFVQNYRNGEI"
     gene            8603..9352
                     /gene="fabG"
                     /locus_tag="KR294_000735"
     CDS             8603..9352
                     /gene="fabG"
                     /locus_tag="KR294_000735"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HBH0238848.1"
                     /translation="MINLTGQVAVVTGGSRGIGKEIAKKLASFGADVVINYTSKEDEA
                     LKTKNEIESMGVKCTSIKCDVSKFDEVNQMIDSVVSEFGKIDILVNNAGITKDGLLMR
                     MKEEDFDRVIDINLKGVFNCTKAVTKPMMKKKYGRIINMTSVVGIMGNAGQTNYCASK
                     AGVIGFTKASARELASRNININAVAPGFIETDMTKVLSDDVKESTLANIPKKSYGKPE
                     DVANAVAFLVSDMSSYITGQVINVDGGMVMQ"
     gene            9406..9630
                     /gene="acpP"
                     /locus_tag="KR294_000736"
     CDS             9406..9630
                     /gene="acpP"
                     /locus_tag="KR294_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HBH0238849.1"
                     /translation="MFNKVVEIIIEQLGVEDKEITMETSLMKDLEADSLDAVEIIMAL
                     EDEFGIEIPDTEAENFKSIGDIVKYIEANK"
     gene            9659..10897
                     /gene="fabF"
                     /locus_tag="KR294_000737"
     CDS             9659..10897
                     /gene="fabF"
                     /locus_tag="KR294_000737"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HBH0238850.1"
                     /translation="MNKRVVITGLGCVTPLGTGKEEFWSNIKSGVSGIDKITNFDAST
                     YQTQIAGEVKNFHPEEYISKKELKRLDKFAQFAIVSAKLAVEDANLDLDKVDRERFGV
                     IIGSGIGGVEAIETQHKILLEKGNKRVSSLFVPMMIGNMAAGQVSIFLGAKGPNTNVC
                     TACASGTHSIGDAFKVIQRGDADIMVAGGSEAAVTGLAFAGFCNMKAMSTRNDDPKTA
                     SRPFDKDRDGFVMGEGAGIVILEDLEHALARGAKIYAEVVGYGLTADAYHMTTPAENG
                     EGAARSMNMALKDGNVPLEEVDYINAHGTSTYYNDLYETMAIKTVFGEKAYDLCVSST
                     KSMTGHLLGASGAIEAVVCAMSIEDSFVPPTINIQEVGEDLDLDYVPNQGKEKNIRYA
                     LSNSLGFGGHNATIVLKKYV"
     gene            11123..12841
                     /locus_tag="KR294_000738"
     CDS             11123..12841
                     /locus_tag="KR294_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBH0238851.1"
                     /translation="MNFRLPKKRLPKKIIFICIILISIILFIKHDQNGLKEREIINKG
                     KYMSESLVADKEYDEAKKVVKTSFESIPEKKYNKVYNEVWDMLKTISYVPDGTKIVID
                     SLEKMRESDVKLSDECRFNIEKRLASVYIMDNNYSKAVDLTVKSIKLAEKLGNNYEKA
                     RLDVDLASIFLKIGGYETGEKLIKDSFKIDIDEGEKNGMVRLYAIINLAEIYVEEGEY
                     DKAIEISSRIKDYKKFVNTDNYNDFDIMASIMQSNAYVGKNNIQKAKTFLEKADYLIK
                     SDRTVYILDKDMYYYMAMGNLEYKSENYNSAIDNYKKSLEISTKRKLTQEKIKNLNKI
                     LNIYEKQGNIESLNEYQKMLINEYKENKSIRDSETSFYIIDKVSNESKLFEKTKKEIK
                     YYKILFTVILIAILGSTFLYNRLKYFKAQNLHDGLTNVYNRKSFDIMYEKYREKDDNF
                     ALVMIDIDNFKLINDNYGHKFGDTVIKGITNTICVMLEQDDKVFRYGGEEFSVLIRNK
                     SGDEVADIIDSIRVAIANKKWNDDVTVTISAGVAHVSDSKDVLEEADKNLYKAKQLGR
                     NKVVYK"
     gene            12872..14872
                     /locus_tag="KR294_000739"
     CDS             12872..14872
                     /locus_tag="KR294_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH0238852.1"
                     /translation="MKQSIAIVTDKITKLSSFLEENIRLVLGNYIDINHYYLEVLKEN
                     DKIQGDFVLVMNDDRLNSMRKHLVQDSKIIVIRRTLKENEIYGLFSIPNGTEVLVVND
                     TKETTLETISLFYKIGVKNLKFTPYIEGKIYKNIDIAITPGVKGKVPSYINKVIDLGN
                     RYIDISTFIEIINGLRIDVKEIRKNLMAYSESLISLDNGVKDNYRQLFLKIEEQDVIL
                     NLSKDGIIFTSADGIINTFNKEALKILGINENPQGKNIEDIISEDLNILLEDKEIIDE
                     VVFTNKKYINVNKKSIFSMGNKAGIYYNLQEITYIKKLEQNLTNKLREQGQIARYTFK
                     DIKTKNKNMVKCVELAKKISKSELSVLIIGESGTGKELLSQSIHNASNRSNQPFIAVN
                     CAAVPDSLLESQLFGYEKGSFTGALREGKKGLFELANNGTIFLDEIGDMPPLLQTKLL
                     RVLQEKQVMPIGSHNVINIDVRVIAATNKNLLKMIREGKFREDLYYRLNVLPIDVPSL
                     RNRKEDIITLMNFFLKNNIRLSPEVITILEKYNWPGNIRELQNVASYVSLMCDSMVFR
                     DDLPPYIRVECANNYEDGFGYTRKEFEEILRILYERRESSSGIGRGFIIEKLIQEGIE
                     ISESKVRKVLSYLSECGYISSKSGRGGSQITSEGIKLYNNIN"
     gene            15223..15468
                     /locus_tag="KR294_000740"
     CDS             15223..15468
                     /locus_tag="KR294_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03905 family TSCPD domain-containing
                     protein"
                     /protein_id="HBH0238853.1"
                     /translation="MKYKTTGTCATEIEFEVKENKVTNVNFIGGCDGNLKGLKVLVEG
                     MNIEDVIQKLKGIECKTKPTSCPDQLSLALENYMNIK"
     gene            15503..16228
                     /locus_tag="KR294_000741"
     CDS             15503..16228
                     /locus_tag="KR294_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HBH0238854.1"
                     /translation="MKPIIGILGNLIIMENGMFPGLERSYVNNDYINAVLKGGGSPVI
                     IPVNTDKEVIKKQIEMVDGVLISGGWDINPQLYGEETREETTFIYPEVDEFDLIAISI
                     ALELKKPILGVCRGLQILNVSLGGTLYQDNNLIEGSYIKHTQSSKRHVATHKVDVKEG
                     SILEGILGKQLLTNSYHHQSVNQLGKGLKAIAYSKDGIIEAIEKEDENFVVGVQWHPE
                     MMVDYCDKMEKLFKYFINICSNL"
     gene            16250..17563
                     /locus_tag="KR294_000742"
     CDS             16250..17563
                     /locus_tag="KR294_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBH0238855.1"
                     /translation="MNEKNKMGLISIILLGINAVVGAGVFLLPGDAMKSFGVASIFVY
                     IFDMLLVLSMAFCFAEVAGKFNKNGAAYVYTKEAFGDFCGFEVGLMKWVIGCISWGAL
                     IVGFPTSLSAVWAPAGEPHIQKIIIVVMIVGLTIINLLGVSLSKIVQNVITVGKLIPL
                     ILFIGIGIFFIKGVNFTSSTMVPPGAGATEFGAAALLMFYSFTGFESIAVAAEDMENP
                     QKNIPIAIISVIVIASIIYILNQVVCVGILGDSLSSTSTPVADAARICFGNMGAGLVT
                     FGTLVSVGGICMCGAFVNPRSCVALADDKMLPRIFARKDKKGTPYVAIIATMLITIPI
                     ALSGSFAELAAISAVARFIQYIPTSLSVLVFRKKRPELVGTFKTPFGAVIPLIAVCVG
                     TWLLFQASMHQLIMGLGALAIGVPLYFIMKSYNRKVYDENLKKIV"
     gene            17769..18308
                     /locus_tag="KR294_000743"
     CDS             17769..18308
                     /locus_tag="KR294_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH0238856.1"
                     /translation="MPTITLKNGVDVLIREGVREDAQSIIDFYNEVGGETHFLSFGKD
                     EYKISLEEQENAIESAKASDNSVKLIAFIDGEIVGIATIDSNQKAKGKHVGVLGIVVK
                     EKYWGIGLGKRLMLDLIEWCKSNGITKKITLVTNEENYNAIGLYKKVGFEVESILKKE
                     CYYNGVYTDLIGMSLLLGI"
     gene            18397..20382
                     /locus_tag="KR294_000744"
     CDS             18397..20382
                     /locus_tag="KR294_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-1,6-bisphosphatase"
                     /protein_id="HBH0238857.1"
                     /translation="MKNLCKISDDYLNSKLKYLKLLSKQYPSISKASTEIINLEAILN
                     LPKGTEHFITDVHGEYEPFVHVLKNGSGVIKRKIEELFSNTIRDSEKKMLATLVYYPE
                     QKLDLIIKQEENIDDFYRINIYRLIELCKYASSKYTRSKVRKLLPENFKYIIEELLHE
                     HVKSEHKEEYYKSIVETIVDIGIAKEFIIAISTVIQKLVVDRLHVIGDIYDRGPRPDI
                     IVDKLIEHHCVDIQWGNHDILWMGAASGEKTCIANALRISARYANLDIVEDIYGINLL
                     PLATFAIEMYKDDPCKEFIPKVNDQSVTTTEKSLMAKMHKAISIIQFKLEGEVIRRRP
                     EFEMEHRLLLNMINYDEGTINLKGKTYKLKDTYLPTIDKKDPYKLTMEERNVIDKLVS
                     SFRGSEKLQKHVSFLFSKGSIYLKANSNLLIHGCVPLNEDGSFMSMNIMGKEYKGKAL
                     MDKMESLAREGFFFKDKAEEKLYGMDIMWYLWTGKCSSLFGKDDMTTFERYFIAEKET
                     HKENKNPYFKLRENEMACKRLFEEFDLELDESHIINGHVPVESKNGESPIKANGKILV
                     IDGGFSRAYQKTTGIAGYTLIYNSRTLQLVSHEPFNSAEEAIANESDILSTTVVVEHK
                     AKRKMVRDTDEGVKIQEEIEDLKLLLMAYKKGLIKEM"
     gene            20606..21574
                     /gene="spoIIIAA"
                     /locus_tag="KR294_000745"
     CDS             20606..21574
                     /gene="spoIIIAA"
                     /locus_tag="KR294_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AA"
                     /protein_id="HBH0238858.1"
                     /translation="MNKLSDEIINSLSTTIREKVEKVSNNNLNIEEIRLRSQKPLILN
                     ANSKDYFYNQKTMTLDLNQQNSYVVTREDVEQTFQIICKYSIHSFMDDIKKGFITLRG
                     GHRVGLVGKAIVEDGQVKNIKHISSLNIRVSREIIGCSDKILSHIIKGKNQINNTLII
                     SPPQCGKTTLIRDIVRNLSNGNEDYGFKGLKVALVDERNEIAGAYLGVPQMDVGIRTD
                     IIETCPKDLGITMLLRSMSPNVIVTDEIGSEKEIKALYTALNGGIGLITTVHGDSIED
                     IQNRKELNRLLDKELFKKVIILSAKRGAGTIEKIYDLEEKRWYFAN"
     gene            21564..22085
                     /locus_tag="KR294_000746"
     CDS             21564..22085
                     /locus_tag="KR294_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AB"
                     /protein_id="HBH0238859.1"
                     /translation="MQIKIIIIAFLIGSSYLIGEQIYKTYTRRHKQLNDLIRVLEILR
                     MDLSFGLYTLEEIFNRIGGNKEFCFWKFFYQISEGLHNEQSKTLEIIISENIDVLSKE
                     TYLGNKEIEELKNLILTLGKSDIESQQRMIDLSIENLKKQTYETKEDINKKGVLYKKL
                     VTFIGIGICIILI"
     gene            22102..22299
                     /gene="spoIIIAC"
                     /locus_tag="KR294_000747"
     CDS             22102..22299
                     /gene="spoIIIAC"
                     /locus_tag="KR294_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018589775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AC"
                     /protein_id="HBH0238860.1"
                     /translation="MEISLILKVAGVGILISVLNMILEKTDRKDWAGLTTLAGVIIVL
                     GMVITEISDLFNTVRTMFQLY"
     gene            22315..22701
                     /gene="spoIIIAD"
                     /locus_tag="KR294_000748"
     CDS             22315..22701
                     /gene="spoIIIAD"
                     /locus_tag="KR294_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AD"
                     /protein_id="HBH0238861.1"
                     /translation="MEIMQLIGIAIISTTLCLVIKKDRPEIANFIAIITGVIILLSVM
                     FKLNFIVDSIQDLANKANIPTMYISLIIKLIGIAYLMEFAIQLCKDCGEGNIASKLEF
                     GGKIIVMSMSFPILLSIVEMVVNIIP"
     gene            22786..23991
                     /gene="spoIIIAE"
                     /locus_tag="KR294_000749"
     CDS             22786..23991
                     /gene="spoIIIAE"
                     /locus_tag="KR294_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AE"
                     /protein_id="HBH0238862.1"
                     /translation="MKKRFLPMIIGFLFTFFFVNIFAIMIFANEVPSSEDKEYGETKN
                     SIDKYIDGQLDKLDINEIQDYINKEIVINDVNLKSFVKDLISGEKNILDLFNKDGLKI
                     LMFDEFKASLKVVAVILVLALLSSILKSLENSFSSGAVSQIATYIIFITMVSLTLIGF
                     KDVLQICYDAIDHTVGLMQVIMPILITFLLLIGFPITSTTLNPIFIGGVTFINVFFKN
                     FLFVSITVAFGILIINNLSKNIRLKRFFSFVKQINYVSIGAMFTVYLGLVSIQGLYVT
                     SFDKFSVKTAKFAIGNFIPVVGGFVSDSVDILLSSSQLIKNIFGGIGLILLVGICLLP
                     VIKILSVIVVYKLAAIIVEPVGEDGISNFLNEVANLMIIMLASVIAITVMFFVTVAIL
                     TSISVVSQG"
     gene            24051..24668
                     /locus_tag="KR294_000750"
     CDS             24051..24668
                     /locus_tag="KR294_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AF"
                     /protein_id="HBH0238863.1"
                     /translation="MLEGIKAWIVSVLIGAFIVNIVDMILPSSKIKPYVNLVLNFMFV
                     FIVITPVVGFFSKDMSLEDRILKSMGNYNKQYVDSTNALAKETGNNSLSKGYEDGLKE
                     VLKLKLDEYGYDLEDIELNGANINNIKIKEKNNSAKSNNSSNEENKNNSTKREEENIN
                     SNDKENSKQVFKKGTEYGLNLNEEKLKNDLIKVLDVSIEDIQIDK"
     gene            24680..25234
                     /locus_tag="KR294_000751"
     CDS             24680..25234
                     /locus_tag="KR294_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AG"
                     /protein_id="HBH0238864.1"
                     /translation="MLKNLNDKDKRKVYSLITIAGICVVSLVLLSCFPSSKSDKQVGK
                     TETNKNAEKQVTKEQEKDDLESKLTAILSKIDGAGDVDVMVTFESSEEIQPAFNSNNT
                     TETTEEKDAQGGERTVTTSSENKTMITSNSSDPVVIKTTEPKIKGVIVVASGASDPSV
                     KETLYSAVQTSLQVAGHQVEIYSK"
     gene            25261..25950
                     /locus_tag="KR294_000752"
     CDS             25261..25950
                     /locus_tag="KR294_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpoIIIAH-like family protein"
                     /protein_id="HBH0238865.1"
                     /translation="MKFNYKGRGFVIITLTAMLVVVGTVNYQLSKKSLLETSKEFKAY
                     EEAQLQKNTDDSYSSKTEDSSNVDKQGGKESADIDIVDSKASKVKEKATETSKEIKAQ
                     LSSEKNMKKASYILDMKMNREKQRNELVQDLNEMINNPSTTEESRKEASNMKLNIVKI
                     QEKELQIENLLSTKGYEEALVYISDNKVNVVVNEAKLEKKDAAKIFDLVAEQANVKYE
                     NIKLTNNNSNK"
     gene            26060..26422
                     /locus_tag="KR294_000753"
     CDS             26060..26422
                     /locus_tag="KR294_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBH0238866.1"
                     /translation="MEDNKFGQVKISNDVIATIAGLAALEVEGIETTATLTDKLLKNN
                     GVKIQIEEEDVNLDVMVTIKYGMSIPDTAFKVQENVKNTVETMTGLKVSQVNIHIQGI
                     SFKKDKVDKEEAKATKKN"
     gene            26507..27013
                     /gene="nusB"
                     /locus_tag="KR294_000754"
     CDS             26507..27013
                     /gene="nusB"
                     /locus_tag="KR294_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HBH0238867.1"
                     /translation="MKKDRAQKSTTREYIMKLIYQININKEDFETLEDKVDNFLKDNS
                     EHIINRYKELALQYSKNTNLKLEDTEIEDVIDKKYINTVCKALKENHDKIDELINKHA
                     KNWTVDRMPKVDVSILRLSVCEILYLDTPNKVSINEAVELAKIYCDDKSPKFINGILG
                     SVVDEIGK"
     gene            26997..28067
                     /locus_tag="KR294_000755"
     CDS             26997..28067
                     /locus_tag="KR294_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-sialoglycoprotein endopeptidase"
                     /protein_id="HBH0238868.1"
                     /translation="MKLGNNIIIGIDTSCYTTSIAAISLDKKVIFNEKIMLEVRDNSK
                     GLRQSEAVFQHINNLGILSDRIKSFKDKFNVEGVCSSKKPRPVENSYMPVFNVGHNFG
                     KLLSSIYGCRFYETTHQENHIEASLLNSKLKNNNKFISVHMSGGTTEILLTSKQDSHH
                     NVCDTNLGKIAKISIKKDDKSKLYNNFGYNIDIIGGSKDISFGQLIDRVGIKLGYKFP
                     SGKYLDENALNCNLKIESGLKTSVRDGYMNLSGLENQVNKIINDNGDNTNQKEYISKL
                     VLDSVVRNMFKSLVYLCETYNVNEVVFAGGVSASKYILRELSMKLRKKHIEAYFTEPQ
                     YSTDNAVGCAIIGLNNFLGERV"
     gene            28064..29269
                     /locus_tag="KR294_000756"
     CDS             28064..29269
                     /locus_tag="KR294_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HBH0238869.1"
                     /translation="MKLRALDISEANSYIKRILINDPILSNLKVKGEISNFKVHSSGN
                     VYLSLKDETSKLNCVIFKSNFNRNLKLDNGVKIIANGYISVYERDGAYQLYINEIEIE
                     GIGNLHIEFNRLKEKLNKEGLFDPKYKIPIPKMPNSIGVITSPTGAVIRDIINVIKRR
                     YPKVNIKLYPVTVQGDKSAEEICEAIRFFNHMKNVDTLIVGRGGGSIEELWSFNDEMV
                     AREVFNSQIPIISAVGHETDFTICDFVSDMRAPTPSAAAEIATPSLDDINYKLGNIKS
                     RMSKSLTNQIELDQYRLETVFNKINNYLDSYTIKDKVIQLDKIYDKIIFGIENNLKLE
                     DEKLVKIGALLHNLSPLATMDRGYSITQKNGKVINSIKGLKIKDSIDIVLKDGNLECM
                     IDKIENKEG"
     gene            29271..29486
                     /gene="xseB"
                     /locus_tag="KR294_000757"
     CDS             29271..29486
                     /gene="xseB"
                     /locus_tag="KR294_000757"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HBH0238870.1"
                     /translation="MNLTYEEAYKRLESILSELESKNASLDESLSLYEEGISLYKHCN
                     KLLDDAKLKISKFNQLGIEEDFKIEEE"
     gene            29489..30376
                     /locus_tag="KR294_000758"
     CDS             29489..30376
                     /locus_tag="KR294_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HBH0238871.1"
                     /translation="MEFKQCLKEKASFVEKVLKEYMPKEEGYQKTVIEAMNYSLSAGG
                     KRLRPILTLEACKIVGGNEDEAIPFAIAIEMIHTYSLIHDDLPALDNDDLRRGRPTNH
                     KVYGEAMGILAGDALLNYAFEVMLAGSINKENPEKYLKAINEIAKGAGIYGMIGGQVV
                     DVESENKQIEKEKLDYIHMNKTAAMMVGCMRAGATIGGANSEQMEEITKYAKNIGLSF
                     QIVDDILDIVGDEAKLGKKVGSDIENHKSTYPSLLGLDKSKEIAHNLIDEAKKSIEKL
                     SDDVDFLKGLAEYIIDREY"
     gene            30406..30843
                     /locus_tag="KR294_000759"
     CDS             30406..30843
                     /locus_tag="KR294_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divergent PAP2 family protein"
                     /protein_id="HBH0238872.1"
                     /translation="MDFFSEIFNNGALGISLIACFLAQFIKIFTGKEKRIELSRILIS
                     GGMPSSHSSFVTSLATVVGIEKGFNSTDFAIITVLALIIMYDAAGVRRAVGKQATILN
                     QMVADIQHGKHIEQKKLKELIGHTPLEVWFGALLGIVTALILM"
     gene            30877..32742
                     /locus_tag="KR294_000760"
     CDS             30877..32742
                     /locus_tag="KR294_000760"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HBH0238873.1"
                     /translation="MYKYLDKVNSPKDIKNMSIEEMDLLAKDIRKFLVKSVSKTGGHL
                     ASNLGVVELTLALHKVFDSPKDKIVWDVGHQSYVHKIVTGRKDCFVSLRQFNGLSGFP
                     KENESPHDIFDTGHSSTSISIATGIACARDIKKENYSVISVIGDGSITGGMALEALNQ
                     LGYIDTNMIVILNDNEMSIDKNVGGMSKYLSSIIRNSTVEKMTDEVDKILNVTQTGEI
                     LSKTAHRFKDKLMYSFSPQDCSFFDSLGIRYYGPIDGHNTKELIDILRKAKHKKGPVL
                     LHVITKKGKGYRFAEEQPDKYHGVSKFDIKTGVTSAKVKSMSISVGEKLVDMANSNEN
                     IVAITAAMPSGTGLNLFESAYPKRYYDVGIAEQHATGFAAGLAKNGMKPYFAVYSSFL
                     QRAYDQVIHDVCITKKPVTFLIDRAGLVGNDGETHHGMFDLSYLNSIPNIVVMAPKDT
                     REMELMMDLSLKLDCPLAIRYPRGSSYYLDKGEYGEIVLGKYEVLDDGQDTVILCIGS
                     MVKHALEAKEILSREGINPTIVNARFLKPIDEGMLKALLKNHKNVVTIEDNIVTGGFG
                     SRINKFIIDNEYNVNILNIAIPEEFVKHGNIDELYDFVGLSPKSIADKIRKLVIE"
     gene            32875..33687
                     /locus_tag="KR294_000761"
     CDS             32875..33687
                     /locus_tag="KR294_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family rRNA
                     (cytidine-2'-O)-methyltransferase"
                     /protein_id="HBH0238874.1"
                     /translation="MKKRIDLLLVEQGYFESRERAKKAIMAGLVFVDNQRCDKAGTEV
                     KEDCSIEVKGNPIPYVSRGGLKLEKAMKNFDLTIDGKVCMDIGASTGGFTDCMLKNGA
                     IKVFSIDVGYGQLAWKLRQDDRVVCMERTNIRNVTIEDTKQFADFASIDVSFISLKLV
                     LPKAKELVRHDGEVVALIKPQFEAGREKVGKKGVVREKSTHIEVIKMISDFSVENGFE
                     ILGLDFSPIKGPEGNIEYLIHLRNGNEGYEFDGETYNNKIVEVVEASHNLDK"
     gene            33707..35386
                     /gene="recN"
                     /locus_tag="KR294_000762"
     CDS             33707..35386
                     /gene="recN"
                     /locus_tag="KR294_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HBH0238875.1"
                     /translation="MILELYMKNCALVEELRLNIDKNLNILTGETGSGKSIIIDALGL
                     CLGDKYDRSFLRKGTDKGLVEAVFFSDNRYLKKILEENDISMEDDNLLVITRLIYSDG
                     KSTARVNGRTVKVSLLKEIASTLIDIHGQHQNQALFNKDTHLKFLDLFGENELEEFKI
                     AYKNVYHKYSEVKKALNCLTENKDEMQIQREIDLLRFQINEIEAANLNKNEYEDLLKQ
                     REVYRNSEKIYNNLNSSYSKLHNGEYNVIDLIGLASKELNDISKYDSVLSEYSDTVER
                     IMYELQDISGEIRNYKDNIDFEPYELEQIELRIDEINNLRRKYGDSIDDIFEYYGKIK
                     DRLDEILNRDERVEQLRSKLMNIEEDLKIKASKLTKARIEVATTLEKILLDELKSLNM
                     KNVMFKVNFEKGPFTLDGVDDIEFMISFNLGEDIKPIYKVASGGEMSRFMLAFKTILA
                     DIDDIDTLVFDEIDTGISGIAAQIVGEKLSDIAKKKQIICITHLPQIAANADTHYCIE
                     KDTSNNRTFTNVSKLNESQRKNEIARLIAGNNITEKTIEHASEIIELAKKC"
     gene            35601..36467
                     /locus_tag="KR294_000763"
     CDS             35601..36467
                     /locus_tag="KR294_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0238876.1"
                     /translation="MNKKDTMHLIFIIVIFILLWYIVVAVSEINKNIESCSNKLDYLS
                     QELMSTKSDISNTINEEMSKSYITKSIDLKVKKIEKKECIIDIDVQLSKLGKNGKVFF
                     MYKEDSDKWNETEMTKHGELSYACEIKINTGSEYDYKVVTSGAISESSDVQKLTKSDY
                     MPEQPIFNSGIRDNREYFIEIVENSNLFNHESEKSKNKVYDNIRLEKVDIIVNEGKKD
                     TIYKAKLAEGLDDGKTNNSNRNQVNYEVSFPKRDIDDIIYIKAKLTYNNGVEYTKDIT
                     EDITMGLQDLEK"
     gene            complement(36560..37051)
                     /locus_tag="KR294_000764"
     CDS             complement(36560..37051)
                     /locus_tag="KR294_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH0238877.1"
                     /translation="MADKMAQNITLQFVEEKDLENLENVKLLFTEYSNSLNIDLCFQD
                     FNNELKTLPGKYKKPSGSLILAFVDENLAGCVALKKLEGKICELKRLYVRNQFRGLKI
                     GKILLEEIIEEAKKFGYTHMRLDTLPSMKSAQGLYEKFGFYDIEPYTYNPIEGARYME
                     LKL"
     gene            complement(37112..37552)
                     /locus_tag="KR294_000765"
     CDS             complement(37112..37552)
                     /locus_tag="KR294_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH0238878.1"
                     /translation="MKLNVRIADINNWHDLVSLSVDKSQLDYIESNALSIAESKFITA
                     WVPVGIYDENSLIGFAMYGRLEDDRVWLDRFMIDSKYQGKGYGKASLDFLVNHLKNEY
                     NCDELYLSIFEDNKMAIKLYKDFGFEFNGELDYGGEKVMVLKSN"
     gene            37713..38771
                     /locus_tag="KR294_000766"
     CDS             37713..38771
                     /locus_tag="KR294_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S55"
                     /protein_id="HBH0238879.1"
                     /translation="MNKINKNFKNIWIILGAVSIFTMVIIFNKNCNVNKETQIEAFTI
                     KNHDKKFVYPMGNIIGVKANTDGVLVLGYEEEDVDYIGGIQIGDNIVKIDNKRIKNSQ
                     DVSEILNKIKKSKVEVTFERKNKYKTEVIETKKENGKYKLGLWVRDKISGIGTMTFYD
                     PSMEKFKAIGHAIKDSDTNELLKIKQGYIYKPEQLKIVKASNEKVGKIKGDFNDSNLM
                     GNFSNNSELGISGNITENHNKEFNVANKEKQLIEVGRPQDVKIGGAVILFEDKNKNIT
                     SYDIKIESIVYDKGNYRDMVIKVVDDKLLEYTGGIVQGMSGAPIIQNNKIIGAITHVF
                     RDNPKKGYGIFIDEMIKL"
     gene            38913..39737
                     /gene="spo0A"
                     /locus_tag="KR294_000767"
     CDS             38913..39737
                     /gene="spo0A"
                     /locus_tag="KR294_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation transcription factor Spo0A"
                     /protein_id="HBH0238880.1"
                     /translation="MGGFLVEKIKIVLADDNKDFCQVLKEYLSNEDDIDILGIAKDGI
                     EALDLVKKTQPDLLILDVIMPHLDGLGVIEKLNTMDIPKMPKIIVLSAVGQDKITQSA
                     INLGADYYIVKPFDFVVFINRIRELVSNRVTQVEPKPRPVQETQMTRSDFVKNVGNIE
                     TEITNIIHEIGVPAHIKGYLYLREAIKMVIDNVELLGAVTKELYPSIAKKFNTTPSRV
                     ERAIRHAIEVAWSRGKVDTINQLFGYTVHNTKGKPTNSEFIAMIADKLRLEHSMVK"
     gene            40150..41271
                     /locus_tag="KR294_000768"
     CDS             40150..41271
                     /locus_tag="KR294_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0238881.1"
                     /translation="MRVEAPIKVDRKTKKLAKRVESGEIAVINHIDIDEVAANSLVEA
                     KIKLVINAAPSISGRYPNKGPGILTENNILIIDNVGEELFEELKEGETIEVVDGKIYR
                     KGKFLGAGEVLDKYEVSHQIKAAYENLAVELDRFIDNTIDYAKKEKGFILGEVEIPKV
                     KTNYANKHVLIVVRGQDYKEDLSTMLSYIEEVKPVLVGVDGGADALIEFGYTPDVIVG
                     DMDSVSDEALKKASEIVVHAYTDGRAPGLKRVEELGLDAVVFPAPGTSEDIAMLIAYE
                     YKAELIVAVGTHSNMIDFLEKGRKGMASTFLVRLKIGSKLIDAKGVNLLYRSKLKIKY
                     IWALIATALFPVLVVASLSPGVQQFIQLMQLKFRVLLQM"
     gene            41289..42164
                     /locus_tag="KR294_000769"
     CDS             41289..42164
                     /locus_tag="KR294_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper transporter"
                     /protein_id="HBH0238882.1"
                     /translation="MHINMKYYIVTIGAIFIALGIGMLVGFNLNNNQQLSEQQANIIN
                     DLDDKFDILKEKNDKLDSDLASVNRDYEEAVNFINKNVDKILAGSLNGKSIGIISANE
                     NDDYTKNIEDIINKSNGSIAFNIILKENITNPEKLKEMSTKLGTDVKNANDAVNYIID
                     TLKKEDASDILTYLQELDVIKFNFIGDTYLKYDSVVIAGGNDAKDSTKQFEKIEKFVV
                     SKLKSENKYLVEVQNTGVKTSYVELYSKNKVATIDNIDEGIGSISLAILLQQGNIVGN
                     FGRLDTATSLLPSIK"
     gene            42188..42880
                     /locus_tag="KR294_000770"
     CDS             42188..42880
                     /locus_tag="KR294_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBH0238883.1"
                     /translation="MDSYISIIIPAYNEESRIKYTLESILDIKQINEIIVVDDGSIDN
                     TAKVVSELENEKIKFFKLDKNRGKGYALNYGIKLAMKNADIIGFLDGDLGSSAKEVEK
                     LIVPILNGEADVTIAKFPPAKRKGGLGFVKGLAKNSVFEMTGVELDATLSGQRIFKRE
                     VLEKFDEIPFGYGVEVGMTIDILKYGFKIKEVLVNMTHNETGRNLKGFIHRGKQYYHI
                     KKVLGQKKKEWR"
     gene            42888..43712
                     /locus_tag="KR294_000771"
     CDS             42888..43712
                     /locus_tag="KR294_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HBH0238884.1"
                     /translation="MKDYILYTILLLTGLFGTYAVIPLFKNLLINGNVLRPNYKKDMI
                     PVSMGIVFLPMIVINGIILAFFTTEFKDLAYIFMFMFGMISMFFAGILDDVIGNRDVS
                     GLKGHFKSLFKGSLTTGGFKALFGGFVGLIVSVAISKDIIDIIVNTLIIALSTNLMNL
                     LDLRPGRAIKAYLFIMVIIFLTLTGFVQVLPLLIVPNVLAYFNYDLKARAMMGDTGSN
                     VLGISIGMLISFGYPFNIRLGWLIFVVIMHIFTEKYSLTKIIEKNKLLNFIDKLGR"
     gene            43717..44784
                     /locus_tag="KR294_000772"
     CDS             43717..44784
                     /locus_tag="KR294_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3866 family protein"
                     /protein_id="HBH0238885.1"
                     /translation="MISKRVGIVESIVSQTETLDDIRVNINGEIQRAYNYPKISGTIN
                     IGDEVVLNTTAVELSLGTGGYHFVITNLNNIESTLTEGGHIMKLRYTPLQIKVDSVEE
                     QESIYHDKFANFKGLEGLSVVVGTLHSMLTPFAASFKRNNPNKKLVYIMTDGASLPIY
                     LSKNVDTLKEKKLIDSTITIGNAFGGDYECINIYTALITAKEILKADAVFVSMGPGIA
                     GTGTKYGFTGIEQGSILDAVKKLEGRAIAIPRISFADKRERHQGISHHSMTVFKEIVN
                     VNVDIPITIYDDEKLNFIKEQINLNGLDKKHNIIYIDNNKTKEDLDYFNLKVKSMGRN
                     YEQDEAFFKAASTAAYYLMEV"
     gene            44786..45322
                     /locus_tag="KR294_000773"
     CDS             44786..45322
                     /locus_tag="KR294_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBH0238886.1"
                     /translation="MVLEEKTISSDRVYTGKVITLKVDTVEIPGQGYQKRELVEVGGA
                     VGIVAITDDNKVVLVKQFRKPIEKPIFEIPAGKLEKNESPKECAERELKEETGYSAKN
                     IKLIHKFFTSAGFSNEIMFVYLATGLTPGENNLDADEFLDVYEIELEEAYNMVLKNDV
                     EDAKTSIGLLLVKDMFKN"
     gene            45390..45995
                     /locus_tag="KR294_000774"
     CDS             45390..45995
                     /locus_tag="KR294_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein M"
                     /protein_id="HBH0238887.1"
                     /translation="MRRTYRKNDFRELNRQIIIIGLLFMMSIVVGSYINKILPGSSNN
                     ILNNINPAVEYYNLNISIKDTVIQNLKSDAIFMGSIALLSLFVVTIPAVLVAFVLKGM
                     SIGYTINSCILALKFKSIKMILIILFKNLIIIPCAIILALISLSYFKEMVYEFKKKNR
                     KNMQFLIKRYILNIIIIIALSLGLQLILNTASIGIIKFLAK"
     gene            46007..46921
                     /locus_tag="KR294_000775"
     CDS             46007..46921
                     /locus_tag="KR294_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBH0238888.1"
                     /translation="MDIIEGYIDYIKDKKKLSENTVASYFMDIKKYMEYINQKSIKLV
                     DIVENDIISYLIKLEKDNVSIATIARMISSIKSFHDYLFLNHICTNNPAKDIKKPKIK
                     KENINILTEEEIERLLNFPKLTTPKLIRDKAIFEVLYGTGIKVSELVEMNIEDIDLDI
                     DYIYCNSCCKNQRVIPLCDITKLYLEKYLKEARPKMAVEGEKSLFVSSLGQRFTRQGL
                     WKVIKKYSNLANIDKNINPTMLRHSFAIHLLNEGANIAVVSKILGNVNLSSLQVYLNH
                     IDKNVRREIKEKHPRNDVDVELQKAEAK"
     gene            46963..48135
                     /locus_tag="KR294_000776"
     CDS             46963..48135
                     /locus_tag="KR294_000776"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HBH0238889.1"
                     /translation="MSRVIWIVIDSVGIGALPDAEKFGDSKDVSTLGNIFKEYPDIQI
                     PNMRNLGIGNIDGIDFFESIKEPIGCFGKCKEMSQGKDTTTGHWEMTGIIVDKPFKTF
                     EHGFSKEIIEEFEKKTGRKVVGNKPASGTVIIDEYGEHQIKTGDVIVYTSADSVFQIA
                     ANEEVIPLEELYNMCKIAREIMMGDNAVARVIARPFIGKKKGEFVRTSNRRDYSLDPF
                     EPTVLDNIKESGLDVLAVGKIEDIFNGKGITDAIHTKSNMDGVDETLNYMKQDNKGLI
                     YSNLVDFDSKYGHRRDPEGYKKALEEFDSRLPEIMANMREDDILIINADHGNDPTYKG
                     TDHTREYIPVMIYGNKIKKGFNLGVKDTFADIGATVADILNVKLPKHGSSFKEDLF"
     gene            48182..48994
                     /locus_tag="KR294_000777"
     CDS             48182..48994
                     /locus_tag="KR294_000777"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HBH0238890.1"
                     /translation="MFEKIAQSSKFINSKSDIKPKIGLILGSGLGDLANDIEDPVAIK
                     YSEIPNFPVSTVAGHAGQLVIGKLEGKEVIAMQGRFHYYEGYSQKEATFPVRVMKELG
                     VEILIVTNAAGGVNKEFKAGDLMLIRDHINFSGSNPLVGKNDDRFGARFPDMSDAYSS
                     KYVDVVKNCAKECNIDVKEGVYMFFSGPNYETPAEVRMAQILGADAVGMSTVPEVIVA
                     SHSNIGVIGISCITNMAAGILNQPLSHEEVIETTQKVKSEFMNLVKTTVKNL"
     gene            49198..50523
                     /locus_tag="KR294_000778"
     CDS             49198..50523
                     /locus_tag="KR294_000778"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HBH0238891.1"
                     /translation="MRMYDIIKKKRDNLELSKKEINYFIENYSKGDIPDYQASALLMS
                     IYLNKMNKQETVHLTEAMMNSGDMINLSEIDGIKVDKHSTGGVGDKTTIALIPLVASC
                     GAPVAKMSGRGLGHTGGTIDKLESIPGFSTEMEISKFIDSVNKSKIAVCGQSAKVAIA
                     DKKIYALRDVTATVDNISLISSSVMSKKLASGADAIVLDVKTGDGAFMKTLEESFELA
                     KSMVDIGTGMNRDTIGIVTDMDEPLGFAVGNSLEVIEAIETLKGNGPKDLVELCEVLG
                     AYMLVLSKVAHDFEDGVEKIRESIKSGTAIQKLKEFIENQGGNKDVVDDYSLFKKSKY
                     KYPVKSTKSGYISKIKAEDVGVSAMILGAGRETKDDILDLSAGIILEKKVGDYVNEGE
                     VLAYMYYNDEQKLSLAKGRFIDSYSIVDSKIEKNKLIYGIVTKEEIKKF"
     gene            50736..51815
                     /gene="mltG"
                     /locus_tag="KR294_000779"
     CDS             50736..51815
                     /gene="mltG"
                     /locus_tag="KR294_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HBH0238892.1"
                     /translation="MNFKENRLKIAVLIIVILIILAGIFVFIQIGPYDKNNKKDVIID
                     VPSGASVGKISDILYENKLIKNELLFKLLVKVSNKAPSIKSGTYLLNQSYSNNDIISL
                     LVSGKIYQDGIKVTIPEGATSKEIIAMLVSKNLGDKATFENLIKKPQEFYDKFPYLKE
                     DGITSLEGFLYPETYYFNSKKQSEEDILSEMLKVFDSKYTDKFKKKQKELNMTLQEVM
                     EMASIIEKEAVLDKDRPIIASVFYNRLKVGMPLQSDATIQYIFEERKKIVTYDDLKID
                     SPYNSYKNKGLPPTPISNPGIKSIEAALYPEKTDYLYFVAKIDGGNNYSTNYQDHLKY
                     VKEYKEARDKQSKDTKATNKENTKK"
     gene            51987..52661
                     /locus_tag="KR294_000780"
     CDS             51987..52661
                     /locus_tag="KR294_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HBH0238893.1"
                     /translation="MSNIVNDLVEDYIRVTLKEKEGFLKDLEIYAEENSVPIIHKEVS
                     DLLKVLLKVQKPKRILEVGCAIGYSSIFFATIIGKDADIITVERNEKMIEKAKENIKL
                     AGFDNNITILEGDAEEKLSQVQGEFDLIFIDAAKGQYKLFFDLVIDKLKDGGLLVSDN
                     ILYKGMVAHDDFVVRRKKTIVKRMRNYLDYICNCDYLSTSLVPIGDGVALSYKESKRG
                     DVDGIK"
     gene            52648..53895
                     /locus_tag="KR294_000781"
     CDS             52648..53895
                     /locus_tag="KR294_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HBH0238894.1"
                     /translation="MELNKVELLAPAGDLERLKIAITYGADAVYIGGEIFGMRSAAKN
                     FSKEDMAEGVAFAHERGKKVFVTVNIIPHNEDFLQLEDYLLELEEIGIDAVIIADPGV
                     LSVIKKVIPNMEIHLSTQANTTNYLSANFWYEHGIKRVVVARELSFDEISEIRAKTPL
                     DMDIEAFMHGAMCISYSGRCLISNYMTGRDANKGSCAQSCRWQYHLVEEKRPGEYFPI
                     YEDERGTFFFNSKDLCMIEYIPELIKSGITSLKIEGRMKTAYYVATVVRAYRMAIDEF
                     YRDPENWKFNPMWMEELKKGSHRHFTSGFYLNKPTTEDQNYQSASYVRNYDFIGIVRE
                     TEDEDGLIVVEQRNKMCVGDEIEVMGPYKETMFTKIEEMYNEEGEAIESAPHPRQIVK
                     LKLSVKVGKDYMLRKVIEEKVEE"
     gene            53967..55631
                     /locus_tag="KR294_000782"
     CDS             53967..55631
                     /locus_tag="KR294_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HBH0238895.1"
                     /translation="MSKKKTPFLKKVGKRSWCIFTIILIIYSVLIYRLVDIQVLKGDK
                     YKQSVESQSVEKVELNSGRGIIYDRNNKKLTDTSKSQVLIVEKEKLNNNYKILELIKK
                     ATKMNDLDIYKAVQEQLTRPIIQIQTKNIDKSMKKELEKNGIMVEEKTMRYAKDGLLS
                     HTIGYIKEDDKSGQSGIEKSMDSVLRNSNEKYISAFKAGDAGNEKSLNILKGSVKTVD
                     NKDKDRHLKTTIDYNIQKKLEQILNKEENPTAAIISEASTGEILAMCSRPNFDQNDIS
                     KSLKGKNGEFENRVIKATYPPGSVFKMVVLFSALENGVIDENYTYNCTGKTKVGNTNE
                     ILRCNKRDGHGFQNLRQAFSNSCNPAFLDIAMKLGKEKILKSAEKLHLFEKVDIGLDE
                     EKIREAPKNISIRNLAIGQENIEFTPLQINQMTQIIANNGTFKPLYLYKSLVDNNMNT
                     IKTYKSSKKEELISPYVCTQVKEYMKSVSRIGTAKDLKDIEGGCGVKTGTAQSSLNKK
                     AIDHGWITGFYPEERPKYVITVLVEGTQKGNKSATPIFKEICESIK"
     gene            complement(55728..56012)
                     /locus_tag="KR294_000783"
     CDS             complement(55728..56012)
                     /locus_tag="KR294_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012063608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBH0238896.1"
                     /translation="MCNEISLLDILGTEANYVLDEVELKVQVGKLYEQLNKILTPRER
                     EIVQLRYGLTPYGYKTQREIAQKLDISRSYVSRIEKKALKKLEKELVQES"
     gene            complement(56035..57552)
                     /locus_tag="KR294_000784"
     CDS             complement(56035..57552)
                     /locus_tag="KR294_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBH0238897.1"
                     /translation="MSVAIYLRKSRADEEAEKQGEFETLSRHKSTLLKLAKEQNLDVI
                     EIKEELVSGESIIHRPKMLELLKEVEENKYDAVLVMDLDRLGRGDMKDQGIILETFKE
                     SKTKIITPRKTYDLTDEFDEEYSEFEAFMARKELKLISRRMQRGRIKSVEEGNFIGTS
                     APFGYDAVTTGRKERILVPNKDADVVRTIFDLYINEDMGCSKISKYLNNLGIKTATGA
                     NWYNSAITNIIKNKVYCGYIQWQKKDYKKSKNPNKIKTVKLRPKDEWIEAKGKHEPLI
                     SEITWKKAQNILKKNGHVSYGNQIKNPLAGIVICKNCGRPLVYRPYADHDYIICYHPG
                     CNKSSRFEFIEAAILKSLEDTVKKYQLKASDIDLDKNNKDSNIEFQKRVLKGLETELK
                     ELGKQKNKLYDLLERGIYDEDTFIERSNNISSRTEEIKDSIKTVKNRLSTVKKDNSKI
                     IEDIKTVLSLYHDSDSLGKNKLLKSVIDKAVYYKSKEQKLDSFELMVHLKLHEDQ"
     gene            complement(57677..58498)
                     /locus_tag="KR294_000785"
     CDS             complement(57677..58498)
                     /locus_tag="KR294_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBH0238898.1"
                     /translation="MIISKKITAILVSFLIMISMVGCAPKESATEVAKKYLDSIKIKD
                     YEVAYNLLSKDSKESVSLEKFEEYQDTLFKLQTLKDYKLGEENKVEKYKYSNKEYTNL
                     VKIKETDTIKYITENKEDTANFDRYFIIEDNEYKLLWHKDFKRALSSNYVKIARSETE
                     KDEDKDYNKAAIDIKKAIEIDDKNPLAYYTQSYIYIELQRYDEALKSIDKYLEYLDKN
                     NEAYKIDASDAYNLRGVIFMSKSEFNKARESYNKALELNPDNEYAKTNLNDIKGL"
     gene            58689..59716
                     /locus_tag="KR294_000786"
                     /pseudo
     CDS             58689..59716
                     /locus_tag="KR294_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861148.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp26"
     gene            59788..59940
                     /locus_tag="KR294_000787"
     CDS             59788..59940
                     /locus_tag="KR294_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0238899.1"
                     /translation="MDNFLFNVLASLTASVVVYLISKLFKKAKSHSRTKSDLRVEFKF
                     IFKSKK"
BASE COUNT        23982 a         6282 c        10885 g        18983 t
ORIGIN      
        1 atgattttta taaatatagt tattttaaaa aactacttta catatattgg atgagtataa
       61 aaatccatag ggccttttac taaatcttta ttgtttttat aatatattga attatatata
      121 tttgtagctt ttatatcata acttatgagt gttttaaaaa tcgtatcatc taatgaaaat
      181 gatatatttg aaaacttgtt tattattttt atttcagatt tattttttat ctcttttaga
      241 atttctctac ctttatcatt aaaagcaagt attcttatat aaggtatagt atctatgttt
      301 tttataagtt gcatgtcgct ttttttaata cctaacaata tattgtttag agttcgtttg
      361 attttggtta aagtgtatcg cttggattta attgctaatt gtagttcatg tagaaattca
      421 gatgtaaaga tatctttata gattctgttt tctatgcctt catttacttc aaaatactct
      481 tttaaagtgt ccatatctct aagtataatt gtttttaaaa tatcaaagaa gaagtcatca
      541 aacataggta aaaaaccatt atctattttt tcatttagga tgttataagt tttttctgga
      601 ataacatttt ttaaatgaaa aaggtctgta ttttctttaa gtgaagttct tatagcagta
      661 gcagaacaaa tatcactctc aatttcttcg gaattatact ctgattggac cctggagata
      721 gtaaatggtt ttatactact gtttaaatgg atgaggtttt ttatgtattc tatacccagt
      781 atgttgtttg atgaatttaa tgtttttgat aattgttcct ttgaataatt ttgtataaaa
      841 ttattttttt tgtcttgatg tatataatca aaaagtgcat tagctctagc tgttggaaat
      901 aacagaccat catctaaata tttttttaaa agtaacttaa attcatttgg ttcatttgct
      961 aaaatttcag ctatattata aagaatttct gtatttcctt cttcactacc aaaacatata
     1021 gaatttatgc agtttagtga atttaaaatt gttatagcac catgagaaaa aatttcagca
     1081 ctttgacaag caaataaagt tggtaattct ataactaagt ctacaccatt ttcgacagca
     1141 atttttgctc tagtgtattt atcaaataaa gctggttcgc ctctttgtag aaaatttcca
     1201 ctcattattg ctacagtatg tgttgcattt gttttttcta tagatttaga taaatgatat
     1261 atgtgtccat tatgaaatgg gttatattca actattaatc caagtatgtt cataaaatac
     1321 tccttttatc tttaattatt ttatatatat cacaatttat tataatatgt ataaaattta
     1381 aatttttaat tataaaatta aaaaacgtaa aaaaatttat aaaaatgtag aaatgttacc
     1441 tacataaaaa actggttaaa tgttattaaa ataactttat tagctcttta tattatatta
     1501 ttataacaaa tgggaaagaa taatctacat taagttaact tgttaatata ttattagtga
     1561 aatacacaat ttaccatact agaaatatga tataatataa aaaaaaagta tatactttta
     1621 tattaaaagg tgatatatta tttatgaaaa tcgtttaatg tatacaataa tatatctata
     1681 acaaaataat aaaagataga gttttattta gacatttatt acaaatcaaa atttattaca
     1741 tattatttat aaaaaaatct aaggaggaaa taataatgaa aatattagta ttaaactgtg
     1801 ggagttcttc attaaaatat caattaatag atatgaataa tgaagaagtt ttatgtatag
     1861 gattggttga aagaatagga atagaaggtt ctatattaaa acatgaaaaa gcaggtagag
     1921 atgataaata cgttgttgaa caaccaatga aggaccacaa agatgcaata gcattagttt
     1981 tagaagctgt tgctcatcca gaatttggtg cagttaaaga aatgaaagaa atagatgcag
     2041 taggacatag agttgtacat gctggagaaa aatttgcaac ttcagtagta ataactccag
     2101 aagtagaaga agctttaaaa gaatgtatag atttagctcc acttcataat ccagcaaaca
     2161 taatgggaat agatgcttgt aaagctatac ttccagatgt accaatggta ggtgtatttg
     2221 atactgcttt ccatcaaaca atgcctaaat cttcatactt atatggttta cctcatgagc
     2281 tatatactaa atatggggta agaagatatg gattccacgg aacttctcat aattatgtat
     2341 ctcagagagc agcagagata ttaggaaaag atataaaaga tttaaaaata gtaacttgtc
     2401 acttaggaaa tggtgcttct atagctgctg ttgatggtgg aaaatgtgta gatacatcta
     2461 tgggattcac tccattagaa ggattaataa tgggaactag atgtggagat atagacccag
     2521 ctatattacc attcttaatg agaaaagaag gtttagatgc tgatggattg gataaattaa
     2581 tgaataaaga atctggagta tatggaatga ctggaatttc tagtgacttc agagatatag
     2641 aagatgcagc taaaaatgga gacgaaagag ctcaagctac attagaagcg tatgttaaaa
     2701 aagtacaaaa atatataggc gcttatgctg ctgaaatgaa tggattggat gttgtagtat
     2761 ttactgcagg cgttggtgaa aatggaaagg ctataagagc agatattgct tctaacatgg
     2821 agtttttagg aatgaaatta gataaagaag ctaatgatgt tagaggaaaa gaaacagtaa
     2881 tatctactgc tgattctaaa gtaaaaatgc ttttaatacc aactaatgaa gaattaatga
     2941 tagctagaga tacattaaga ttggtaaaat aattaaatta aacctatgcc tatcaagtaa
     3001 aaatacttga caaacaaatg ctagatttgt ataataaatt tggtgatatg ttgaggtgaa
     3061 cttaatgaaa gttagcatag aaaaaataaa tagaaaagaa actgacaaaa tagacttgaa
     3121 tttttgtgaa aaaattgata ctattagtta ttgtgatgag atttacaaat tagtatcacc
     3181 tgtaaattta aaagggaaag tgtcaaagac taataaaggt ttgtatctag atatagatgt
     3241 caattttaca attgttgaca attgttcaag atgtcttaaa gaagtagaaa taccactaga
     3301 gtattctata caaggttttt tagtaaaaga agaagattat gatgaagatg agtttgagga
     3361 atttgatcct tttatattcg atggtgaaga aatcgacctt attgatataa tagaacagac
     3421 attagatttt aatgtacctc ataaagttct ttgtagtgaa aactgtaaag gtctttgtca
     3481 agtatgcggg gcaaacttaa atgaagaaga gtgttcttgc agtgaaatta caaacgatga
     3541 ggaatacata gatcctcgtt ttgctaaatt aaaagattta tttaattaaa ttttgactaa
     3601 ggaggtggcg taaatggcag taccaaagcg taaaacgtct aaatcaaaca caaaaatgag
     3661 aagagcagct aactcaaaga tggaagcaac aggatttgta agttgcccac aatgtcatga
     3721 gccaaaatta ccacatagag tgtgtccaga ctgtggatat tataaaggta aagaagttgt
     3781 gtctaagtaa tagcttctaa aaagcatgta gagtatactc tacatgtttt ttttgtacat
     3841 ataaaaaaat aagatgattt actagagaaa ataagtggat tttatgcata ttaaaaaata
     3901 gaaaaataat aatataagta ttgaaaattt ttgtgtgtta ctatatacta ctattagtag
     3961 ctggtactaa ttacagctat aaaatttgga gggaacatga aaaagaaaag taaagcccaa
     4021 agacaaaaag agcttataga tatgctaaag acagatcctt tttatactga tgaagaatta
     4081 tcaagtctgt ttgatgtaag tatacagacc ataagattag atagaatgag tctaaacata
     4141 ccagagctaa gagaaagagt caaatcaata gcagaaactc agagttcaaa agtaaagact
     4201 ttaggagtaa aggaaattac aggagaaatc attgatttat ctgtagggcg attaggtata
     4261 tctatgttag aagttacaca ggacatgatt tactctaaga ctaatacttt aaaagatacg
     4321 tatatttttt ctctagcaga ttcattggca atggctataa tagatgcacc taaggttatt
     4381 atgagagttg caaatgtaaa aagttttaag ttgatagaac aacaagatag acttatagca
     4441 aaagcagaag tgtatagaaa tatagataaa aagcattatg taaaagttgt tatcaacaat
     4501 aaagcccaag agcaaatatt tagaggaaag tttatctttg aagaattaga ttaggaggga
     4561 aattatgaaa atagtaattg atggaatggg tggagataat gcacctaaat ctaatgtaga
     4621 aggcgcagta aatgctataa aagaatatca ggttgattta ataatcacag gagataaaga
     4681 tttacttgaa aaggaatttt caaattatga atttgataga aataaattag agatagttca
     4741 tactactgag attatagaaa acgaagataa accagtaaag gctataagaa gtaaaaaaga
     4801 ttcatctatg gtagtagcat taaatcttgt aaaagaagga aaggcagatg ctataatatc
     4861 agctggaaat acaggagcct tacttgctgg tggattattt gttgttggta gaataaaagg
     4921 aatcgataga ccttgcttat gttcagcaat accaaatgta aagcgaggaa tgacacttat
     4981 agcagactgt ggcgcaaatg cagattgtaa acctaagaat ctagttgaat ttgcagctat
     5041 gagtaatatt tattcaagaa aagttttagg tcttgaaaat cctaaggtag cattagcaaa
     5101 tgttggacta gaagaaggca aaggcaatga tttagtcaaa aggtcatatg aagaaattaa
     5161 aaaattagat ttaaatttta tagggaatgt agaagctaga gaagttataa atgcatacac
     5221 agatataatc atatgtgatg gatttacagg taatatatta cttaaatctg ctgaaggtgt
     5281 agcactttca gttatgagtc ttataaagga aacttttatg gccagtacaa aaagtaaaat
     5341 aggagcatta cttataaagg atgatttaag aaaattaaaa agttttatag attattctga
     5401 gtatggggga gctccacttt taggtctaaa tggaggagtt ataaaagctc atggtagttc
     5461 tgatgctaaa gctataaaaa atgctataaa tcaaggaata aaattttcaa agggaaaagt
     5521 cgttgaagat attaaccaat ttataagcaa atacaatgaa gaaaataaaa ataacgaaga
     5581 tgaataaact cgttttggag gtttaatata taatgaatac aaaggctgga atattaggag
     5641 taggaagtta tctacctgag caatcatatg ataattttca cttcgaaaaa ataatggata
     5701 catcagatga gtggataagt actagaactg gtattaagga aagaagattt gccaaagagt
     5761 ctgaagcaac ttctgactta gcatctaaag ctgccttaaa agctatagaa tgtgcaaagt
     5821 taaacgtaga ggatatagag ctgattatat tagctacaat tactcctgat atgtctttgc
     5881 cttcaactgc atgtatagta caagatgcaa taggagcagt aaatgctact gcatttgata
     5941 tatcagcagc ttgttctgga tttgtatatg gagtaactat tgcaaagcaa tttgtggaaa
     6001 caggttgcta taaaaatgtg cttgtaatag gagcagaaac ttgttctaag tttttaaatt
     6061 atgatgatag aacaacagca gtattgtttg gagatggagc tggagcagct gttattggcc
     6121 ctgtaaatga gggtggaata ctgtctacac atatgggctc tgatggtaaa ggaaaagatt
     6181 gtttaaaagt acctgctgga ggttcaagac ttaaggcaag taaagagact gtagaagcta
     6241 atctacatac aatagaaatg gcaggtagtg atgtgtttaa atttgcagtt agaaagatgg
     6301 cagaaacttc tttaagagct cttgaaaaag caaatctaaa tacaactgat atagactact
     6361 tagtgccaca tcaagctaat ataagaatca tacaagcttc ttctaagaga ttagagcttg
     6421 atatgaaaaa agtttatgta aatatagaca aatatggaaa tatgtctgct gcatctatac
     6481 cagtagcatt agatgaagct tatagagaag gtaaaattaa aaagggtgat aatgtagttt
     6541 tagttggctt tggtggaggt ctaacttggg gggcttcagt tgtcaagtgg actttatagt
     6601 ataaaatatc taaaatgatt taattaacaa aattaaactt atacacaaaa taaagttgat
     6661 taataataaa aagtttactt ttatgatttc aagtgaagga gaattgtatg aataaaattt
     6721 gcaaaatatt aaatataaaa tacccagtta tccaaggggg aatggcatgg gtagctactg
     6781 catcattagc aagtgctgta tctaatgcag gaggacttgg cataatagca gcaggaaacg
     6841 caccaaaaga agctataaag aaagaaattg ttgagtgtaa aaaattaaca gataaacctt
     6901 ttggagtaaa tgtaatgctt atgtcgccat ttgttgatga tataattgat ttgattatag
     6961 aagaaaaagt tcaagttatt actactggtg ctggaaatcc tgcaaagtat atggatagat
     7021 taaaggaagc tggaacaaag gttattcctg tagtacctac aatagctttg gcacaaagaa
     7081 tggaaaagct aggagctaca gcagtaatag cagaaggtac tgaaggtgga ggacatatag
     7141 gagaacttac tactatggtc ttagttccac aagttgctga tgctgtaaac atacctgtaa
     7201 tagctgctgg aggaattgta gatggtagag gaattgcagc atcatttgca ttaggtgcca
     7261 gtgcagttca agtaggaact agatttattt gcagtgaaga gtgttctgtc cattcaaact
     7321 ataaaaactt agtactaaaa gcaaaagata gagatgcaat tgtaacagga agaagtactg
     7381 gtcatccagt aagaacatta aaaaataaac tatcaaaaga atttttaaag atggaacaaa
     7441 atggagctac tcctgaagaa ctggataaaa aaggtacagg agctttaaga tttgcaacag
     7501 tagatggaga catagaaaaa ggttcattta tggcaggtca aagtgctgct atggtaaaag
     7561 aaataacacc ttgtaaggaa attatagagg ctatggtaaa tcaagcaaga gagattatgc
     7621 cagcaataga actgtaaatc aggaggagca agatgggaaa agttgcacta gtattccctg
     7681 gtcaaggagc tcaatatgta ggtatggcca aggatttata tgaaaataat actgttgcta
     7741 aaagtgtaat agatgaggct agtgatgcct taaatatgga tttaaaaaac cttatgttta
     7801 atggaaatga agaagaactt tctaaaactg aaaacactca acctgctatg gttacacata
     7861 gtgtagctgt attaaaagca gtacaagccc aagtagattt aaaatatagt gcatgtttag
     7921 gtttatcttt aggagagtat agtgcattgg ttgcagcaga tgcaattgac tttaaagatg
     7981 ctgtatgctt ggtcaaaaaa agaggtaagt ttatgcagga tacagttcca acaggtgttg
     8041 gagctatggc agcaatttta ggtctagata gaagtatatt agaaaatgta gttaaagata
     8101 tacaaggagg tattgtggaa gtagcaaatt ataattctcc tggtcaaata gttatatctg
     8161 gtgaaaatga aaagatagaa gaagcaatgg tgaaatgcaa agaagcagga gcaaaaagag
     8221 ctgttaaatt aaatgtaagt ggaccttttc actcatcaat gctaagagaa gctggtgtaa
     8281 aattggccag tgaattagaa aaagttaaca taactaaacc taaagttgat gtggtggcaa
     8341 atgtaaatgc agattactat aaaaacgaag gtaaagacct gcttataaaa caagtaagtt
     8401 catctgttct ttgggaagat tctatagaaa gacttttaaa tgatggatat gatactttta
     8461 tagaaatggg acctggaaaa actttaaaag catttattaa gaaaatagct tccaataaaa
     8521 aagcaaatgt caatatttat aatatagatg gtatagattc tcttaatgaa tttgtacaaa
     8581 attatagaaa tggagagata taatgataaa tcttacagga caagtagcag ttgttactgg
     8641 tggctctagg ggtataggaa aagaaatagc aaaaaaacta gcatcttttg gagctgatgt
     8701 agtaatcaat tatacttcta aagaagatga agcactaaaa actaaaaatg aaatagaaag
     8761 tatgggggta aagtgtacct ctataaaatg tgatgtgtct aaatttgatg aagtgaatca
     8821 aatgatagat tctgttgtaa gcgaatttgg aaaaattgat atattggtta ataatgcagg
     8881 cataactaaa gatggtctgc ttatgagaat gaaagaagaa gattttgata gagttataga
     8941 tataaactta aaaggtgtct ttaattgtac aaaagcagtt actaaaccta tgatgaaaaa
     9001 gaagtatgga agaataataa atatgacttc agtagttgga attatgggta atgcagggca
     9061 aactaattat tgtgcatcaa aagcaggtgt aattggattt acaaaagctt ctgcaagaga
     9121 gttagcatca agaaacataa atataaatgc agtagcacct ggatttatag aaacagatat
     9181 gactaaagta ctaagtgatg atgtaaaaga atcaacacta gcaaacatac caaagaaatc
     9241 ttatggtaaa ccagaagatg tagccaatgc cgtagcattt ttagttagtg acatgtcaag
     9301 ttatataaca ggacaagtaa taaatgtaga tggtggaatg gtaatgcaat aataatttaa
     9361 aaagtagaga aatctattaa aataaaaaat tttaggaggt acacaatgtt taataaagtt
     9421 gtagaaataa taatagagca attaggagta gaagataaag aaataactat ggaaacatca
     9481 ttaatgaagg atttagaagc agattcatta gatgcagtag aaataataat ggcacttgaa
     9541 gatgaatttg gtatagaaat accagataca gaagcagaaa acttcaaatc tataggagat
     9601 atagttaagt atatagaagc taataaatag tcgagcttta aaaaagtgga ggtatccgat
     9661 gaataaaaga gtagtaataa caggacttgg atgtgttacg ccgttgggaa caggaaaaga
     9721 agagttctgg agtaatataa aatctggagt atctggtata gataaaataa ctaattttga
     9781 tgctagcaca tatcaaactc agatagcagg agaagttaag aattttcatc cagaagaata
     9841 tataagtaaa aaagaattga agagattaga taaatttgct caatttgcaa tagtatctgc
     9901 taaattagca gttgaagatg caaatcttga tttagataaa gttgatagag aacgttttgg
     9961 tgttataata ggttctggaa taggtggagt tgaagctata gaaactcaac ataaaattct
    10021 tttggaaaaa ggaaataaaa gagtaagttc actttttgta cctatgatga taggaaatat
    10081 ggcagctggt caagtttcaa tatttttagg agcaaaaggg cctaacacta atgtatgtac
    10141 agcttgtgca tcaggaactc attcaatagg tgatgctttt aaggtaattc aaagaggtga
    10201 tgcagacatc atggtagcag ggggttctga agctgctgta acaggtcttg cttttgctgg
    10261 attctgtaac atgaaggcta tgtcaactag aaatgatgac cctaaaactg catcaagacc
    10321 atttgataaa gacagagatg gttttgtaat gggagaagga gcaggtattg ttatcttaga
    10381 agacttagaa catgctttag caagaggcgc taaaatatat gcagaagtag ttggatatgg
    10441 tttaactgct gatgcatacc atatgacaac tccagctgaa aatggagagg gagcagctag
    10501 gtctatgaat atggctttga aagatggaaa tgttccatta gaagaagtag attatataaa
    10561 tgctcatgga acttcaactt attacaatga tttatatgaa actatggcta taaaaactgt
    10621 atttggagaa aaggcatatg acttatgtgt gtcatcaaca aaatctatga ctggtcactt
    10681 attaggagca tcaggtgcta tagaggctgt tgtttgtgct atgagtatag aagatagttt
    10741 tgtgcctcca actataaaca tacaagaagt tggtgaagat ttggatttag attatgttcc
    10801 aaatcaaggt aaagaaaaaa atattagata tgcactatca aattctttag gatttggtgg
    10861 gcataatgct acaatagtac taaaaaaata tgtataaata aatattaaat ataaaactaa
    10921 aaaacaagca cttgttttaa ctgtataaat ttatattagc ttaaatttaa agtctcctaa
    10981 attattttag gagacttttt tattaagatt taagtctagc atatgttgta aatcattttg
    11041 atatattgta ttattaatta ttaagaggtt atttatatat gtaagttttc attctacaat
    11101 atacaaaagg aggactaaaa ttttgaattt tagactacca aagaaaaggt tacccaaaaa
    11161 gataattttt atatgtataa tacttattag tattattttg tttataaagc atgaccaaaa
    11221 tggattgaaa gaaagagaaa ttataaataa gggaaaatat atgtctgaaa gccttgtggc
    11281 agataaggag tatgatgaag caaaaaaagt ggttaagact tctttcgaat ctattccaga
    11341 aaaaaaatac aataaagtat ataatgaagt ttgggatatg ttaaagacta tttcatatgt
    11401 tccagatgga acgaagatag tcattgattc tttagaaaag atgagagaat cagatgtgaa
    11461 attatctgat gaatgtagat ttaatataga aaaaagatta gcatcagtgt atataatgga
    11521 taataattat tctaaggcag tagatttaac tgtaaagtct ataaagttgg ctgagaaatt
    11581 ggggaataat tatgaaaaag caagactaga tgttgatttg gcgagcatat ttttaaagat
    11641 aggtggctat gaaacaggag agaaattaat aaaggattct tttaaaatag atattgatga
    11701 aggtgaaaaa aatggaatgg ttagattata tgctattata aatctagcag aaatatatgt
    11761 agaagagggc gaatatgata aagctattga aataagtagc aggataaaag attataaaaa
    11821 gtttgtaaat acggataatt acaatgattt tgatataatg gcctctataa tgcagtcaaa
    11881 tgcgtatgtg ggcaaaaata atatacaaaa ggcaaagact tttttagaaa aagctgatta
    11941 tcttataaaa tcagatagaa cagtttatat attagataaa gatatgtact attatatggc
    12001 aatgggaaac ttagaatata aaagcgaaaa ttataattct gcaatagata attataaaaa
    12061 aagtttagag atatctacta aaagaaagtt aacccaggag aaaataaaaa atttaaataa
    12121 gatattaaat atatatgaaa aacaaggaaa tatagaatct ttaaatgagt atcaaaagat
    12181 gttaataaat gaatataaag agaacaaaag tataagagat tcagagacta gtttctatat
    12241 aattgataaa gtatcaaacg aaagtaagct atttgaaaaa actaaaaaag aaataaaata
    12301 ttataaaata ttatttacag taattttaat tgctatatta gggtctactt ttttatacaa
    12361 ccgattgaag tattttaaag cacaaaattt acatgatggt cttacaaatg tttataatag
    12421 aaaaagtttt gatattatgt atgaaaagta cagagagaaa gatgataatt ttgcacttgt
    12481 gatgatagat attgataatt tcaagctcat aaatgataat tatggacata aatttggtga
    12541 cactgttata aagggaataa caaataccat ttgtgttatg ttagaacaag atgataaagt
    12601 ctttaggtac ggaggagaag aattttctgt attaataaga aataaatctg gtgatgaagt
    12661 agcagatata attgacagta taagggttgc aattgcaaat aaaaagtgga atgatgatgt
    12721 gactgtgact ataagtgcag gtgtagctca tgtttcagat agcaaagatg tactagaaga
    12781 agctgataaa aatttatata aagcaaaaca acttggtaga aataaagtag tatataagta
    12841 attatatact atataaataa gaggtataaa tatgaaacaa tcaatagcta tagtaactga
    12901 taaaataact aaactatcat ctttcttaga agaaaatata cgtttggttt taggtaatta
    12961 tattgatata aaccactatt atctggaagt tttaaaagag aatgataaaa tacaaggtga
    13021 ttttgtacta gtaatgaatg atgatagatt aaacagtatg agaaagcatt tagtacaaga
    13081 tagtaagatt atagtgataa ggagaacact taaagaaaat gaaatatatg gattattttc
    13141 aataccaaat ggaactgaag tattggttgt aaatgataca aaagaaacta ccttagaaac
    13201 gataagctta ttttacaaaa taggagtaaa aaatttaaag tttactccat atattgaagg
    13261 aaaaatttat aaaaatatag acatagctat aacgcctgga gtaaagggaa aagtaccaag
    13321 ttatataaat aaagtaatcg accttggaaa tagatatatt gatatatcta cctttataga
    13381 aataataaat ggtcttagaa tagatgttaa agaaatacgt aaaaatttaa tggcatattc
    13441 tgagagttta ataagtttag ataatggagt taaagataat tataggcaac tgtttttaaa
    13501 aatagaagaa caagatgtta tattgaatct atcaaaagat ggaataatat ttacttcagc
    13561 agatggtata ataaacacat ttaataaaga agctttaaaa attttaggta taaatgaaaa
    13621 tccacaaggc aaaaacatag aagatatcat ttctgaagat ttaaatattt tacttgaaga
    13681 caaagaaata attgatgaag tggtatttac aaataaaaaa tatataaatg taaataaaaa
    13741 aagtattttt tctatgggga ataaagctgg gatatattat aacttacaag aaataacgta
    13801 tataaaaaaa ttagaacaaa atcttactaa taaattaaga gaacaaggtc agatagcaag
    13861 atatacattt aaagatataa aaactaaaaa taaaaatatg gtaaagtgtg tagaattggc
    13921 taaaaaaata tctaaatcag aactttctgt attaataata ggagaaagtg gtactggtaa
    13981 agaattatta tcacaatcaa ttcataatgc ttccaataga agtaatcaac cgtttatagc
    14041 agttaattgt gcagcagttc cagatagtct attagaaagt caactgtttg gatatgaaaa
    14101 aggctctttt acaggagctt taagagaagg aaaaaagggt ctatttgaac ttgctaataa
    14161 tggaactata tttctggatg aaattggaga tatgcctcca ttgctacaga caaagttact
    14221 aagggtatta caagaaaagc aggttatgcc tataggttcc cataatgtta taaacataga
    14281 tgttagggtc atagcagcaa caaacaaaaa cttactaaag atgattagag aaggaaaatt
    14341 tagagaggac ctgtattata gactaaatgt attgccaata gatgtaccat cattgaggaa
    14401 tagaaaagaa gatataataa cacttatgaa tttctttttg aaaaacaata taagactttc
    14461 gccagaagtt ataactattt tagaaaaata taattggcca ggaaatataa gagagttaca
    14521 aaatgttgct tcttatgtaa gtctaatgtg tgatagtatg gtttttagag atgacttacc
    14581 accatatata agggtagaat gtgctaacaa ttatgaagat ggatttggtt atacaagaaa
    14641 agaatttgag gaaatactga ggattctata tgaaagaaga gagtcatcct ctggaattgg
    14701 aagagggttt ataatcgaaa agcttataca ggaaggtatt gagatttctg aaagcaaagt
    14761 tagaaaggtg ctatcttatt taagtgaatg tggatacata tcatctaaat ctggtagagg
    14821 aggaagtcaa ataacctcag aggggataaa actttataat aatataaatt aagctaagta
    14881 tttgatattg aaatcacata ttttgaattt agatatttaa ataataataa acttttatat
    14941 ttatagagat taatttatat tatgtcagaa agaatattgt aatttataat taaatattaa
    15001 taggttttta aaataggatt agataggtaa taggttaagt tagaataacc cattacctat
    15061 ttttatttgt aagaaaagtg tacatagaat tagaagtaaa aaatacaact aataaaacta
    15121 ttgaaaatac tagataaata ataaataaaa ataattatag attttggcat acatattgct
    15181 aattatagag ataagacgac aaaataattg ggaggtttaa tgatgaaata caaaacaaca
    15241 gggacttgtg ctacagaaat tgaatttgaa gtaaaagaaa ataaagttac aaatgtaaac
    15301 tttataggtg gatgtgatgg aaatttaaaa gggctaaaag tattagttga aggcatgaat
    15361 atagaagatg taatacaaaa gttaaaagga atagagtgta aaacaaagcc aacatcttgc
    15421 ccagaccaac tgtctctagc attggaaaat tatatgaata taaagtaata cataaaacaa
    15481 tcgattagtt aggagtttaa ttatgaaacc aataataggg attttaggaa atttaataat
    15541 aatggaaaat ggtatgtttc caggtcttga aaggtcatat gtaaataatg attatataaa
    15601 tgcagtgcta aaaggaggag gtagtccagt aataattcct gtaaatacag ataaagaagt
    15661 tataaaaaaa cagattgaaa tggttgatgg agtcttaata tctgggggat gggatatcaa
    15721 tcctcaactg tatggagaag aaacaagaga agaaacgaca tttatatatc cagaagtgga
    15781 tgaatttgat ttaattgcaa taagtatagc attagaactt aaaaagccta tattaggtgt
    15841 atgtagggga ctacaaattt taaatgtaag tttaggagga actttatatc aagataataa
    15901 tcttatagaa ggaagttata taaaacatac acaatcttct aaaagacatg tagctactca
    15961 taaagttgat gttaaagaag gaagtatttt agagggaatt ttaggaaaac aattacttac
    16021 aaatagttat catcatcaaa gtgtcaatca gcttggaaaa ggattaaaag ccatagcata
    16081 ctcaaaagat ggtataatag aagctattga gaaagaggat gaaaattttg tagtaggagt
    16141 acagtggcat ccagaaatga tggtagatta ctgtgataaa atggaaaaac tatttaaata
    16201 ttttataaat atttgttcaa atttataata taccttgggg ggattgaaca tgaacgaaaa
    16261 gaacaaaatg ggattaataa gtattatact tttaggtatt aatgcagtag taggagctgg
    16321 agtttttcta ttaccaggag atgcaatgaa atcatttggt gtagcaagta tatttgtata
    16381 tatatttgat atgttgttag ttttatctat ggcattctgt tttgctgagg ttgcaggtaa
    16441 attcaataaa aatggtgctg cctatgtata tacaaaagaa gcttttggag atttttgtgg
    16501 ttttgaagta ggtcttatga aatgggtaat aggatgtatt tcttggggag ctttaatagt
    16561 aggttttcct acatcattat cagcagtatg ggctccagca ggtgaaccac atatacaaaa
    16621 aattataatt gtagtcatga tagttgggct tacaattata aacttattag gtgtatctct
    16681 atcaaaaatt gtacaaaatg ttataactgt aggtaaacta attccattaa tactatttat
    16741 aggaataggt atatttttta taaaaggagt taattttact tcttcaacaa tggtacctcc
    16801 aggagctgga gcaacagagt ttggagcagc agcactttta atgttttatt catttacagg
    16861 atttgaatct atagcagttg cagcagaaga tatggagaat ccacaaaaaa atataccaat
    16921 agcaattata agtgtaatag taattgcatc aataatatat atattaaatc aagttgtatg
    16981 tgttggtata ctaggagatt cgttatctag tacatctaca ccagtggcag atgctgcaag
    17041 aatatgcttt ggaaatatgg gagctggatt ggttaccttt ggaaccttgg tttctgttgg
    17101 tggaatttgt atgtgtggtg cttttgtaaa tccaagaagc tgtgtagctt tagctgatga
    17161 taaaatgtta ccgagaatat ttgcaagaaa agataaaaaa ggtacaccat atgtagcgat
    17221 aatagctact atgctaatca ctataccaat agctctatct ggaagttttg ctgaattagc
    17281 agcaataagt gcagttgcta gattcataca atacatacca acatctttat ccgtattagt
    17341 gtttagaaag aaaagaccag aattagtagg tacttttaaa actccttttg gagcagtgat
    17401 tcctctaatt gctgtatgtg ttggaacatg gttattattc caagcatcta tgcatcaatt
    17461 aattatggga ttaggagctt tggcaattgg agtaccatta tactttataa tgaagtctta
    17521 taatagaaaa gtctatgatg aaaatttaaa gaaaatagtt taattatgtt ataacaattt
    17581 attgagttaa aattagacat tggcataaaa ttaaatacaa ataagtatct acaaggctat
    17641 attaaaatat tattaatttt ttattttaat atagccttat attgttatca ataaatgaaa
    17701 aatattgtaa caatagaaga acaatagtat tatgtttata gacaaaaaac ttattaggag
    17761 gtaaatttat gccaacaata acattaaaaa atggtgtaga cgtacttatt agagaaggtg
    17821 taagagaaga tgctcaaagc attatagatt tttataatga agtgggtgga gaaactcatt
    17881 ttctgtcatt tggaaaggat gaatataaaa tatctttgga ggaacaagaa aatgctatag
    17941 aatcagcaaa agcatccgat aattctgtta aactgattgc atttatagat ggtgaaatag
    18001 ttgggattgc aacgattgat tctaatcaaa aagcaaaagg aaagcatgtt ggagtattag
    18061 gaattgttgt aaaagaaaaa tattggggaa ttggattggg taaaaggctt atgttagacc
    18121 ttatagaatg gtgtaaatca aatggaataa ccaagaagat aactcttgtc actaatgaag
    18181 aaaattataa tgctatagga ttatacaaaa aagttggatt tgaagtagaa agcatactaa
    18241 agaaagaatg ttattataat ggtgtttata ctgatttaat aggaatgtca cttttattgg
    18301 gaatataatt agtgtacatt ttatctcgaa aaaagtatat taagtatggt ataattaaaa
    18361 aagaatataa cttaatataa ttttggagga cgaattatga aaaatctgtg taaaatatca
    18421 gatgattatt taaacagcaa gcttaagtat ttaaagttat tatcaaaaca atatccaagt
    18481 atatcaaaag caagtacaga aataataaat ttagaggcta tattaaatct tccaaaggga
    18541 acagagcatt ttataacaga tgtacatggt gaatatgaac catttgtaca tgtattaaaa
    18601 aatggttctg gtgtaataaa gagaaaaata gaagaattgt tttcaaatac aataagagac
    18661 agcgaaaaaa aaatgttagc aactcttgta tattatcctg aacaaaagtt agacctaata
    18721 attaagcaag aggaaaatat agatgatttt tatagaataa atatttatag acttatagaa
    18781 ctttgtaaat atgcttctag caaatatact aggtctaaag ttagaaaact gttaccagaa
    18841 aattttaaat acataataga agaacttttg catgagcatg ttaaaagtga acataaagaa
    18901 gagtattata aaagtatagt tgaaacaata gttgacatag gaatagctaa ggagtttata
    18961 attgctattt ctacagttat acaaaaattg gttgtagata gacttcatgt aataggagat
    19021 atttatgata gaggtccaag accagatata attgtcgata agcttattga acatcattgt
    19081 gtagatattc aatggggaaa tcatgatata ttgtggatgg gtgcagcctc aggtgaaaaa
    19141 acttgtatag caaatgcact gaggatatca gctagatatg cgaatttaga cattgtagaa
    19201 gacatatatg gaataaatct attgccttta gccacttttg ctatagaaat gtataaagat
    19261 gacccttgta aagaatttat tccaaaggtt aatgaccaaa gtgtaacaac aacagaaaag
    19321 tctttaatgg caaaaatgca caaagcaata agtataattc aatttaagct tgaaggtgag
    19381 gttatcagac gaagacctga atttgaaatg gaacatagac tcttgcttaa tatgataaac
    19441 tatgatgaag gtacgattaa tttaaaaggt aaaacatata aattaaaaga tacttattta
    19501 cctacaatag acaaaaaaga cccatataaa ttaactatgg aagaaagaaa tgttattgat
    19561 aaattagtat cttcatttag aggtagtgaa aaattacaaa aacatgtttc atttttgttt
    19621 tctaaaggaa gtatatattt aaaggctaac tcaaatttac tgattcatgg atgtgtaccg
    19681 ttaaatgaag atggaagctt tatgtctatg aatataatgg gaaaagagta taaaggtaag
    19741 gctcttatgg ataagatgga gtctctagca agagaaggat ttttctttaa agataaggca
    19801 gaagaaaaac tgtatggcat ggatattatg tggtatttat ggactgggaa atgttcatca
    19861 ttatttggta aagatgatat gactacattt gaaagatact ttatagctga aaaagagact
    19921 cataaagaaa ataagaaccc atattttaaa cttagagaaa atgagatggc ttgtaaaaga
    19981 ttatttgaag aatttgattt agaacttgat gaatctcata taataaatgg tcatgttcct
    20041 gtggagagta aaaatggaga gagcccaata aaagctaatg gtaaaattct cgttatagat
    20101 ggtggttttt ctagggctta ccaaaaaact actggtatag ctggatacac tttgatatac
    20161 aattctagaa ctttgcaatt agtatcgcat gaaccattta attctgctga agaagccatt
    20221 gcaaatgaaa gtgatatctt atcgacaact gttgtagtag agcataaggc aaagagaaaa
    20281 atggtgagag atactgatga aggagtaaag atacaagagg aaatagaaga tttaaaacta
    20341 cttttaatgg cttataagaa agggctaata aaagaaatgt agatgttata gaggcacttc
    20401 atgattgaag tgtctttttg ttaatactta ttaaatatat tataaagatt aataatagta
    20461 gtttatatta tacttactaa gtgaatccaa gataaatggg ttcacttttt ttatttataa
    20521 acattattaa aaaaatatag atgttttggt tatattcctt gtcctttata aatagaatta
    20581 tataaacaaa ggaggaggac aagagatgaa taaactttct gatgaaataa taaactctct
    20641 ttctacaact ataagagaaa aggtagaaaa agtctcaaac aataatctga acatagaaga
    20701 aattaggtta cgctcacaaa aaccattgat actaaatgca aactctaaag attattttta
    20761 caatcaaaaa actatgacac ttgatttaaa tcaacaaaac tcatatgtag taacaagaga
    20821 agatgtagag caaacttttc aaataatatg taaatattca atacattcat ttatggatga
    20881 cataaaaaaa ggattcataa ctttgagagg aggtcataga gtagggttag ttggaaaagc
    20941 aatagtagaa gatggacaag tcaaaaatat aaagcatata tcatctttaa atataagggt
    21001 atcaagggaa attattggat gctcggataa gattttaagt catatcataa agggaaaaaa
    21061 tcagattaat aatactttga taatatcacc acctcaatgt ggaaaaacaa ctttaataag
    21121 agatatagta agaaatttaa gtaatggtaa tgaagattat ggatttaaag gtttaaaagt
    21181 ggctttagta gatgagcgta atgagatagc aggagcttat ctaggtgttc cacaaatgga
    21241 tgtgggaata aggactgata taatagaaac ttgcccaaaa gacttgggta ttacaatgct
    21301 tttaaggtct atgtcaccaa atgttattgt gacagatgaa attggaagtg aaaaagaaat
    21361 aaaggcatta tacacagcat taaatggagg tataggatta ataactactg tgcatggaga
    21421 ttcaatagag gatatacaaa atagaaaaga attaaataga cttctggata aagagttatt
    21481 taaaaaggtt ataattcttt ctgcaaaaag aggagcagga acaattgaaa aaatttatga
    21541 tttagaagaa aagagatggt attttgcaaa ttaaaataat tattatagct ttcttgatag
    21601 gaagtagtta tttgataggt gaacaaatat acaaaactta tactcgtaga cataaacaat
    21661 taaacgattt aataagagtt ttagaaattt tgaggatgga tttatctttt ggactttata
    21721 cattagaaga aatctttaat aggataggtg gaaataaaga gttttgtttt tggaaatttt
    21781 tctatcaaat atcagaagga cttcacaatg aacaaagtaa aactttggaa ataataatat
    21841 cagaaaatat tgatgtctta agtaaagaaa cttatctagg caataaagaa attgaggaac
    21901 tgaaaaatct aatacttact ttagggaaaa gcgatataga gtcacaacaa agaatgatag
    21961 atttatctat agaaaatttg aaaaaacaaa cctatgagac aaaggaagat ataaacaaaa
    22021 aaggcgtatt gtataaaaaa ttagtgacat tcataggtat aggtatatgt attatattga
    22081 tttaatatgg ggaggtttat tatggaaata tcattgatat taaaggttgc aggtgtcggt
    22141 attctaatat cagtattgaa tatgatattg gaaaaaacag atagaaaaga ttgggcaggt
    22201 cttactacat tagcaggtgt aataatcgta ttgggtatgg taataacaga aataagtgac
    22261 ttgtttaata ctgtaagaac aatgtttcaa ctttactaaa gaggagggag taatttggaa
    22321 ataatgcaat taataggaat tgcaatcatt tcaactacac tctgtttagt aattaaaaaa
    22381 gatagaccag agatagcaaa tttcatagct ataataactg gagtaataat actattgtca
    22441 gttatgttta agctaaattt tatagtagat agtatacaag atttggctaa caaggctaac
    22501 atcccgacta tgtatatatc attaataata aaattaattg ggatagcata cttaatggaa
    22561 tttgcgatac aactttgtaa agattgtggg gaaggaaaca ttgcttcaaa actagaattt
    22621 ggaggtaaaa taatagttat gtcaatgtct ttccctatac ttttgtccat tgtagaaatg
    22681 gtggtgaata taattccata gatgtgtatc ttggaatgaa tataagtata ttagagagct
    22741 tttgttgtat tgaggtttat agagtgaaga gaggcatggt tgcttatgaa aaaaagattt
    22801 ttaccaatga ttataggttt tttatttact ttcttttttg taaatatctt tgctattatg
    22861 atatttgcta atgaagtacc aagtagtgaa gataaagaat atggtgaaac aaaaaatagc
    22921 atagataagt atatagatgg tcaattagac aagctagata taaatgagat tcaagactat
    22981 ataaataaag aaatagttat taatgatgtt aatttaaaat catttgtaaa agatttaatt
    23041 agtggagaaa aaaatatctt agatttattc aataaagatg gattgaagat attgatgttt
    23101 gatgaattta aagcaagttt aaaggtagta gcagtaattt tggtactggc tctgttatca
    23161 tctattttaa agagtctgga aaactctttt tcatcaggtg cagtaagtca aatagcaaca
    23221 tatataatat ttatcacaat ggtatcactt acacttattg gttttaaaga tgtattacag
    23281 atttgctatg atgcaataga ccatactgta ggtcttatgc aagttataat gccaatatta
    23341 ataacatttt tacttttaat tggattccca ataacgtcga ctactttgaa tcctatcttc
    23401 ataggaggag taacatttat aaatgtattt tttaaaaatt ttctatttgt atctattact
    23461 gttgcatttg gaattttaat aataaacaat ttatcaaaaa atataaggct aaagagattt
    23521 ttctcctttg taaaacaaat aaattatgtt tctattggag ctatgtttac tgtttactta
    23581 ggtcttgtat ccatacaagg attgtatgta accagttttg ataaattcag tgtaaagact
    23641 gctaaatttg ctataggtaa ttttattcct gttgtaggtg gatttgtatc tgactctgtg
    23701 gatattttat tatcttcatc tcagcttata aaaaatatat ttggaggaat agggcttatc
    23761 ttacttgttg gaatttgctt acttccagta ataaaaattt tatcagtaat agtagtgtac
    23821 aaattagcag caataattgt agagcctgtt ggagaggatg gaatatctaa ttttttaaat
    23881 gaagtggcaa atttaatgat aataatgcta gcatcagtaa ttgctataac agtaatgttc
    23941 tttgtaactg tagctatctt gacctcgata agtgtcgtaa gtcaagggta atttatatat
    24001 cagtgaaaaa taattacatt taatctaatg tttttagaga ggaggatgct atgttagagg
    24061 gcataaaggc atggatagtt agtgttttga taggagcatt tatagtaaat atagtagata
    24121 tgattttacc aagttctaag ataaaacctt atgtcaacct agttttaaac tttatgtttg
    24181 tatttattgt aataactcca gtagtaggat ttttttcaaa agatatgagt ttagaagata
    24241 gaatattaaa atctatggga aactacaaca agcagtatgt agatagtaca aatgctttgg
    24301 caaaagagac tggaaataat agtctatcca agggatatga ggatgggtta aaagaagtac
    24361 ttaaattaaa acttgatgaa tatggttatg atttagaaga tatagagctt aatggggcaa
    24421 atataaataa tataaaaata aaagaaaaga ataatagtgc aaaaagtaat aacagttcca
    24481 atgaagaaaa taaaaataat agtactaaaa gagaggaaga aaacataaac tctaatgaca
    24541 aagaaaattc taaacaagtc ttcaaaaaag gtacagagta tgggttgaac ctaaatgaag
    24601 aaaaattaaa aaacgactta ataaaggtgc tggatgtttc tatagaagat atacaaattg
    24661 ataaatagga gttgggagaa tgttgaaaaa cttaaatgac aaagataaga gaaaggtata
    24721 ttcactaata actatagcag gaatatgtgt ggtttcatta gtattattat cttgttttcc
    24781 tagtagcaaa agcgataaac aagttggaaa aacagagact aataaaaatg ctgaaaagca
    24841 agtcactaaa gaacaagaaa aagatgattt agagtcaaaa ttaacagcaa tactatctaa
    24901 aattgatggt gcaggagacg ttgatgtaat ggttacattt gaatcaagtg aagaaataca
    24961 acctgctttt aattcaaata atacaacaga aacaacagag gaaaaagatg cacaaggtgg
    25021 agaaagaaca gttacgactt ctagtgaaaa taaaacaatg ataacttcaa attcaagtga
    25081 ccctgtagtt ataaaaacta cagagccaaa gataaaggga gtgatagtgg tagcaagtgg
    25141 agcaagtgac ccaagtgtta aagagacact ttatagtgca gtacaaacat cattacaagt
    25201 agctggtcat caagtagaaa tatattctaa ataaatacat ataaccgggg ggataaatga
    25261 atgaagttta attataaggg aagaggattt gtaataataa ctttaactgc aatgttagtg
    25321 gtagtaggaa cagtgaatta tcaactaagt aagaaatctt tattagaaac atcaaaagag
    25381 tttaaggcat atgaagaagc acagttgcaa aaaaatactg atgatagtta tagtagtaag
    25441 acagaggatt ctagtaatgt agataaacaa ggtggtaagg aaagtgctga tattgatata
    25501 gtcgatagca aagctagtaa agtaaaagaa aaggcaactg agacaagtaa ggaaataaaa
    25561 gctcaattat catcagagaa aaatatgaaa aaggcatctt atattttaga tatgaaaatg
    25621 aatagagaaa aacaaagaaa tgagttagtt caagatttaa atgaaatgat aaataatcca
    25681 tctacaacag aagaatctag aaaagaagct tctaatatga aattaaatat agttaaaatt
    25741 caagaaaaag aacttcaaat agaaaacctt ttgagtacaa aaggatatga agaagcgtta
    25801 gtttatataa gcgataacaa agttaatgta gttgtaaatg aagctaaatt agaaaagaaa
    25861 gatgcagcaa aaatatttga tttagttgca gaacaagcca atgtgaagta tgaaaatatt
    25921 aaacttacaa ataataatag taataagtaa agtataaacc tcagaattaa ctgaggttat
    25981 tttcttgcaa agtagacttg tatttggtat tattatactt ataaaaatag ttccttaaaa
    26041 tcaggaggta agttttaata tggaagataa taaatttgga caagtaaaaa tatctaatga
    26101 tgtaatagct acaatagctg gtttagcagc attagaagtt gaaggcatag aaactacagc
    26161 aacattaaca gataagttgt taaaaaataa tggagtaaaa atacaaatcg aagaagagga
    26221 tgttaattta gatgtaatgg ttacgataaa gtatggaatg tcaataccag atacagcttt
    26281 taaagttcaa gaaaatgtaa aaaatactgt tgagacaatg acaggactga aggtttctca
    26341 agtaaatata cacattcaag gaatcagctt taagaaggat aaagttgata aagaagaagc
    26401 aaaagcaact aagaaaaatt aatattagcc ctctgaaaag tcagagggtt ttttgctggt
    26461 aattgatttt atatggataa ttaaacttaa aggagaattt tgattgatga aaaaagatag
    26521 ggcacaaaag agtacaacaa gagaatatat aatgaaactt atataccaaa taaatattaa
    26581 taaagaagat tttgaaactt tagaagataa agtagataat tttttaaaag ataattcaga
    26641 acatattata aatagatata aagaacttgc acttcaatac tcaaaaaata caaatttaaa
    26701 gttagaagat actgaaattg aagatgttat agacaaaaaa tatataaata cagtatgcaa
    26761 agcattgaaa gaaaatcatg acaaaataga tgagttaata aataagcatg ctaaaaactg
    26821 gacagtagat agaatgccaa aggtagatgt ttctatactt agattgtctg tgtgtgaaat
    26881 actttattta gacactccta ataaagtatc aataaatgaa gcagtagaac ttgcaaaaat
    26941 atattgtgat gataagtctc ctaaatttat aaatggtata ttgggaagtg ttgttgatga
    27001 aattgggaaa taatataata attggaattg atactagctg ctatactact tctatagcag
    27061 ctatctcttt agataagaaa gttatattca atgaaaaaat aatgttagaa gtaagggata
    27121 attcaaaagg tttaaggcaa agtgaagctg tatttcaaca tatcaataat ttagggattc
    27181 ttagtgatag gataaaatct tttaaagata agtttaatgt agaaggagtt tgctcatcaa
    27241 aaaaaccgag acctgttgaa aactcatata tgcctgtatt caatgtaggt cataattttg
    27301 gaaaattatt gtctagtata tatggttgta gattttatga gactactcat caagagaatc
    27361 atattgaagc aagtttatta aatagtaaat taaaaaataa taataaattt atttctgttc
    27421 atatgtctgg tggtactaca gagatacttt taacaagcaa acaagatagt catcacaatg
    27481 tatgtgatac taatttaggt aaaattgcca aaataagtat taaaaaagat gataaaagta
    27541 agttatacaa taattttgga tataatatag atataattgg aggaagtaaa gatattagct
    27601 ttggtcaact tatagataga gtaggaatta agcttggata taaatttcct tcaggaaagt
    27661 atttggatga aaatgcttta aattgtaatc ttaaaataga aagtggtctg aaaacttctg
    27721 taagagatgg gtatatgaat ttatcaggat tagaaaatca ggtaaataag attataaatg
    27781 ataatggaga taatactaat caaaaagaat atatatctaa attagtatta gattcagtag
    27841 ttagaaatat gtttaaatct ctagtgtatt tatgtgaaac ttataatgta aatgaagtag
    27901 tatttgctgg tggagtttct gcaagtaagt atattcttag agaattaagc atgaagttaa
    27961 gaaaaaagca tatagaagct tattttacag aaccacaata ttcaactgat aatgctgtcg
    28021 ggtgtgctat aataggattg aataactttt taggagaaag agtatgaaac taagagcttt
    28081 agatataagt gaagcaaact catatattaa aagaatttta ataaacgacc caatactttc
    28141 taatcttaaa gttaaaggag aaatttctaa ttttaaggtt catagtagtg ggaatgtata
    28201 tttatcactt aaagatgaaa catcaaagtt aaactgtgta atttttaaaa gtaattttaa
    28261 tcgcaattta aaattagata atggtgtaaa aattatagct aatggatata tatcagtcta
    28321 tgaaagagat ggtgcgtatc aattatacat taatgaaatt gaaatagagg gaataggaaa
    28381 tttgcacata gagtttaata gattaaagga aaaacttaat aaagaaggat tatttgaccc
    28441 taaatacaag atacctatac ctaaaatgcc aaactcaatt ggcgttataa catctccaac
    28501 aggtgctgtt ataagagata taataaatgt aataaaaaga agatatccga aagttaatat
    28561 aaagctttat ccagtaacgg ttcaaggaga taaatcagct gaagaaatct gtgaagcaat
    28621 tagatttttc aatcatatga agaatgttga tacacttata gttggtagag gtgggggttc
    28681 aatagaagaa ctttggtctt ttaatgatga aatggtagca agagaggttt ttaattctca
    28741 aattccgata atatcagcag ttgggcatga aacggatttt actatttgtg actttgtgtc
    28801 tgatatgaga gccccaacgc catcagcagc agctgagatt gctactccat cattggatga
    28861 tataaactat aaacttggaa acataaaaag taggatgagt aagtctctta caaatcaaat
    28921 agagctagac caatataggt tagaaacagt atttaataag ataaataact atttagattc
    28981 gtacacaata aaagataaag ttatacaatt agacaaaata tatgataaaa taatttttgg
    29041 aatagaaaat aatttaaaat tagaagatga aaaattagta aaaattggag cattactcca
    29101 taatttaagt ccattagcta ctatggatag aggttatagt ataactcaaa aaaatggaaa
    29161 agtaataaat agtataaaag gattaaaaat aaaggatagt atagatatag tattaaaaga
    29221 tggaaattta gaatgtatga tagataaaat tgaaaataaa gagggatagt atgaatttaa
    29281 cctacgaaga agcttataaa agattagaaa gtattttaag tgaattagaa tctaaaaatg
    29341 ctagcttgga tgaatcttta agcctatatg aagaaggtat aagcctttat aaacattgta
    29401 ataagctttt agatgatgct aaattgaaaa taagtaaatt taatcaattg ggaatagaag
    29461 aagactttaa aatagaggag gaataaaatt ggaatttaaa caatgtctaa aagaaaaagc
    29521 aagttttgta gaaaaagtac ttaaagaata tatgcctaaa gaagaagggt atcaaaaaac
    29581 tgttattgaa gctatgaact atagcttaag tgctggaggt aaaagattaa gaccaatact
    29641 tacattggag gcttgtaaaa tagttggagg taatgaagat gaagctattc cttttgctat
    29701 tgcaattgaa atgatacata catattcact aatacatgat gatttgccag ctcttgataa
    29761 tgatgattta agaagaggaa gaccaacaaa tcataaagta tatggagaag ctatggggat
    29821 tttagcagga gatgctttgt taaactatgc ttttgaagta atgcttgcag gctcaatcaa
    29881 taaagaaaat ccagaaaagt atctaaaagc tataaatgaa attgccaaag gtgctggtat
    29941 atatggaatg ataggtggtc aagtagtaga tgtagaaagc gaaaataaac aaattgaaaa
    30001 agaaaaatta gattatatac atatgaataa aactgctgca atgatggtag gctgtatgag
    30061 agcaggagct actataggtg gagcaaattc tgaacaaatg gaagaaataa ctaaatatgc
    30121 aaaaaatatc ggattatcat tccagatagt agatgatata ctagacatag taggagatga
    30181 agctaagtta ggtaaaaagg ttggaagtga tatagaaaat cataagtcaa catacccatc
    30241 tcttttaggt ttagataaat ctaaagaaat tgcacataat ttgattgatg aagcaaagaa
    30301 aagtatagaa aaattatctg atgatgtaga ttttttaaag ggattggctg aatatataat
    30361 agatagagaa tactaaaata tacagctaaa atcgaggagg gaaaaatgga ttttttttcg
    30421 gagattttta acaatggggc tttgggaata agtctgattg cttgtttctt agcacaattt
    30481 ataaaaatat ttactggtaa ggaaaaaaga attgagttat caagaatact tatttcagga
    30541 ggtatgccta gttcccatag ttcttttgtt acaagtttag ctacagtggt aggtattgaa
    30601 aaagggttta attctactga ttttgctata attaccgtgc ttgccttaat tataatgtat
    30661 gatgcagcag gtgttagacg ggctgttggt aaacaagcta ctatattaaa tcaaatggtg
    30721 gcagatatac agcatggaaa gcatatagag cagaagaaat taaaagaatt aataggtcat
    30781 acaccactag aagtttggtt tggagcttta cttggaatag taacagcttt aatattgatg
    30841 taaattgaaa atttacagaa taaaggtgag gataatatgt ataaatattt agataaagta
    30901 aattctccaa aggatataaa aaatatgagt atagaagaaa tggatttact tgcaaaggat
    30961 ataagaaagt tcttagtaaa atctgtttca aagacaggag gacacttagc ttctaatcta
    31021 ggagtggttg agttaacatt agcacttcat aaagtatttg atagccctaa agataagatt
    31081 gtatgggatg tagggcatca atcttatgtt cataaaatag ttactggaag aaaagattgt
    31141 tttgtatctt tgagacagtt taatggacta agtggttttc caaaggagaa tgaaagtcct
    31201 catgatattt ttgatacagg acatagcagt acatctattt ctatagctac aggtattgcc
    31261 tgtgctaggg atataaaaaa agaaaactat agtgttatat ctgtgatagg agatggttct
    31321 ataacaggag gtatggcact tgaagcttta aatcaattag gatatataga taccaatatg
    31381 atagtaatcc ttaatgataa tgagatgtcc atagataaaa atgttggagg aatgtctaaa
    31441 tatctgtcaa gtattataag aaactcaaca gttgagaaaa tgacagatga agttgataaa
    31501 attttaaatg ttacacaaac aggtgaaatt ttatctaaga ctgcacatag atttaaagat
    31561 aaactaatgt atagcttttc tcctcaggac tgttcatttt ttgattcatt aggtataaga
    31621 tattatggac ctatagatgg ccataatact aaagaactaa tagatatatt gagaaaagct
    31681 aaacacaaaa aagggcctgt tcttttacat gtaattacga aaaaaggaaa agggtacaga
    31741 tttgcagaag aacaacctga taaatatcat ggagtatcaa agtttgatat aaagacaggt
    31801 gttacatctg caaaagttaa gtctatgtca attagtgttg gagaaaaact tgttgatatg
    31861 gctaatagta atgaaaatat agtagcaata acagctgcaa tgccatctgg tacagggtta
    31921 aacctgtttg aaagtgcata tccaaaaaga tattatgatg ttggtatagc tgaacaacat
    31981 gcaacaggat ttgcagcagg tcttgcaaaa aatggtatga aaccttactt tgctgtgtac
    32041 tcatcatttt tgcaaagggc atatgaccaa gttattcatg atgtatgcat aacaaaaaag
    32101 ccagttactt ttcttataga tagagctgga ttagttggaa atgatggaga aactcatcat
    32161 ggtatgtttg atttaagtta cttaaattct attccaaata ttgtagtaat ggctccaaaa
    32221 gacacaagag agatggagct tatgatggat ttgtcattaa aattagattg tccactagca
    32281 attagatacc caagaggaag tagttattac ctagataagg gagagtatgg agagattgta
    32341 ctgggtaaat atgaggtatt agatgacggt caagatacag tcatactttg tattggaagt
    32401 atggtaaaac atgctttaga ggctaaagaa atattatcaa gagaaggaat aaatccgaca
    32461 atagttaatg ctagattctt aaagccaatt gatgaaggta tgttaaaagc attattaaaa
    32521 aatcataaaa atgtagttac tatagaggat aatattgtaa ctggaggatt tggaagtaga
    32581 ataaataagt ttattataga taatgaatat aacgtaaata tacttaatat agcaatacca
    32641 gaagaatttg taaaacatgg caatatagat gaattatatg actttgtagg attatcgcca
    32701 aaaagtattg ctgataagat aaggaaatta gttattgagt aaaaatctaa tgtagatatt
    32761 gtaaattaaa atttatataa aatatagaat ttatcaatta gaataaatat caagtgtgtt
    32821 acttcaagct actttagtta tcattaaagt agcttttaac agaaaggtaa ttgtatgaaa
    32881 aaaagaatag atttattatt agtagaacaa gggtactttg aaagtagaga aagagccaaa
    32941 aaagcaataa tggctggatt ggtttttgtt gataatcaaa ggtgtgataa ggctggtaca
    33001 gaagtaaaag aagattgtag tatagaagta aaaggaaatc caataccata tgtcagtaga
    33061 ggtggtttaa agcttgaaaa agcaatgaaa aactttgatt tgactattga tggaaaggta
    33121 tgtatggata taggggcatc cacaggtggt tttacagatt gtatgctcaa aaatggagca
    33181 ataaaagtat tttctataga tgttggttat ggtcaacttg catggaaatt gagacaagat
    33241 gatagggttg tgtgtatgga aagaaccaat ataagaaatg tgacaataga agatacaaag
    33301 cagtttgctg attttgcgtc aattgatgtg tcttttatat cgttaaagtt agtacttcca
    33361 aaggcaaagg agttagtacg tcatgatggg gaagttgtcg ctttaattaa acctcaattt
    33421 gaagcaggaa gagaaaaagt aggtaaaaaa ggagtagtta gagaaaaatc tacacatata
    33481 gaagttataa aaatgatttc tgatttctca gtcgaaaatg gatttgagat tttagggtta
    33541 gatttttctc ctattaaagg tcctgaaggt aatatagaat atctaattca tttgagaaat
    33601 ggaaatgaag gatatgaatt tgatggtgag acatacaata acaaaatagt agaagttgtt
    33661 gaagcttctc ataatttaga caaataggtt aaaagggggc ttagatttga tcctcgaatt
    33721 atatatgaaa aattgtgcct tagttgaaga actaaggttg aatattgata aaaacttaaa
    33781 tatacttaca ggtgaaactg gttcaggaaa atctataata atagatgcac ttggactttg
    33841 tttaggtgat aaatatgata ggtctttttt aagaaaagga acagataagg gacttgttga
    33901 ggctgtattt ttttcagaca atagatatct taaaaaaata ttagaagaaa atgatataag
    33961 tatggaagat gataatttat tggtaataac taggttgata tactcagatg gtaagagtac
    34021 tgctagagta aatggaagga ctgttaaagt gtctcttctt aaagaaattg catctacact
    34081 tatagatata catggtcaac atcaaaatca agctttgttt aataaagata ctcatttaaa
    34141 atttctagac ctttttggag aaaatgaatt ggaagagttt aaaattgctt ataaaaatgt
    34201 gtaccataag tatagtgaag taaaaaaagc tttaaattgc ttgacagaaa ataaagatga
    34261 gatgcaaatt caacgagaaa tagatttatt aagatttcaa ataaatgaaa ttgaagctgc
    34321 aaatctaaat aagaatgaat atgaagattt attaaaacaa agagaagttt atagaaatag
    34381 tgaaaagata tataataatc taaattcgag ttatagcaag ttacataatg gtgagtataa
    34441 tgttattgac ctaataggtc ttgcatctaa ggaacttaat gacatatcta aatatgacag
    34501 tgttttaagt gaatatagtg atactgtaga aagaatcatg tatgagttac aagacatatc
    34561 tggtgagata agaaattaca aagataatat agactttgaa ccttatgagc tagagcagat
    34621 tgagcttaga atcgacgaga ttaataactt aagaagaaaa tatggagaca gtatagatga
    34681 tatatttgag tattatggaa aaattaaaga tagattagat gaaatattaa acagagatga
    34741 aagagttgaa cagttaagaa gcaaactgat gaatatagaa gaagatttaa aaataaaagc
    34801 cagtaaattg actaaagcaa gaatagaagt agcaactact ttagaaaaaa tacttcttga
    34861 tgaattaaaa agcttaaata tgaaaaatgt aatgttcaag gttaattttg aaaaaggtcc
    34921 atttacttta gatggagtag atgatattga atttatgata tcttttaact taggagaaga
    34981 tattaagcct atatataaag ttgcatcagg tggtgagatg tccagattta tgttagcgtt
    35041 taaaaccata ttggctgata tagatgatat tgatacatta gtgtttgacg agatagatac
    35101 tggaataagt gggatagcag cacagatagt tggtgagaaa ttgagtgata tagcaaagaa
    35161 aaaacagata atatgtataa ctcatttacc tcaaattgct gcaaatgcag acactcatta
    35221 ttgtatagag aaagatactt caaataatag gacgtttacc aatgttagta agttaaatga
    35281 atctcaacga aaaaatgaaa ttgccagact tatagcaggt aacaatataa cagaaaaaac
    35341 tattgaacat gcaagtgaaa ttattgagtt ggctaaaaaa tgttagtgaa aaacaagcat
    35401 tttaataggt gtaaagaatt tttatagaaa tgctttacat ctatttttta tgatgaaatt
    35461 attttaaaat atctagtgcc tatattgaag aaaagtaggt ttgaaaatgg aatgaacttt
    35521 gtataaattt gtaactttga aatttctaaa tgcttaagta taatattatt tattaaggta
    35581 gtagtgaggg gaggcataaa atgaataaaa aagatactat gcacttaatt tttataattg
    35641 taatttttat tttattatgg tatattgtgg tagcagtaag tgagattaat aaaaatattg
    35701 aaagttgtag taacaaatta gattatttgt cacaagagct tatgagtact aagtcggata
    35761 ttagtaatac tataaatgaa gaaatgtcaa aaagctatat aacaaaaagt attgacttaa
    35821 aagtgaaaaa aatcgagaaa aaagaatgta ttattgatat agatgttcaa ttaagtaaac
    35881 ttggaaaaaa tggaaaagta ttttttatgt ataaagaaga tagtgataaa tggaatgaaa
    35941 ctgagatgac aaaacatgga gaattatcat atgcatgtga aattaagata aatacaggaa
    36001 gtgaatatga ctataaagta gttacaagtg gagctatatc tgaaagttct gatgtgcaaa
    36061 aattgactaa atctgattat atgcctgaac aacccatatt taattctggg ataagagata
    36121 atagagaata ctttattgaa atagtagaaa atagtaatct tttcaatcat gagagtgaaa
    36181 agtcaaaaaa taaagtttat gataatatta gattagaaaa agtagatatt attgtaaatg
    36241 aaggaaaaaa agacactata tacaaagcca aattagctga aggcttagat gatggcaaaa
    36301 ctaataattc aaatagaaat caagtgaatt atgaagtaag ttttcctaaa agggatattg
    36361 atgacataat ttatattaaa gctaaactta catacaataa tggagtagaa tatacaaagg
    36421 atataactga agatataact atgggattac aagatttaga aaaataaata catatttaaa
    36481 taaatattca aatagatttg ttcaataaaa tagagtataa ataaaactgt agtagtttta
    36541 cttatactct attaaaaaat tataatttta attccatata tctagcccct tcaattggat
    36601 tataagtata aggttctata tcataaaaac caaacttttc gtataatcct tgtgcacttt
    36661 tcatgcttgg aagagtatct aatctcatgt gtgtatatcc aaatttttta gcttcttcaa
    36721 tgatttcttc caatagtatt tttcctattt ttaatcctct aaattgattt cttacatata
    36781 atctttttaa ttcacatatt ttaccttcaa gtttttttaa agcaacacaa cctgccaaat
    36841 tttcatcaac aaatgccaat atcaatgagc ctgaaggttt tttatatttt cctggaagtg
    36901 tttttaattc attattaaag tcttgaaaac ataagtctat atttagagaa tttgaatatt
    36961 cagtaaatag aagttttacg ttttcaaggt tttctaaatc tttttcttca acaaattgta
    37021 aagttatatt ttgagccatt ttatccgcca ttatatacac atgtttatat aatgacttca
    37081 cctccttgat atatgtatat ttttcttaat atcaattaga ttttaatacc attacttttt
    37141 caccaccata gtcaagctct ccattaaact caaatccaaa atctttataa agcttaatag
    37201 ccattttatt gtcttcgaat atactaagat atagttcatc acagttatat tcatttttaa
    37261 gatgatttac aagaaaatct aatgatgctt ttccatatcc tttaccttga tattttgaat
    37321 caatcataaa tctatcaagc caaactctat catcttctaa acgaccatac atagcaaatc
    37381 ctattaaaga attttcatca tatattccaa caggtaccca agctgttata aatttagatt
    37441 cagcaataga aagtgcattg ctttctatat aatctaactg acttttatct acagacaaac
    37501 taactaaatc atgccaatta tttatgtctg caattcttac atttaatttc aagatattac
    37561 cgcccttcaa actttttgtt acaatctaat actatcatat tatgtattaa aaatcactta
    37621 ttaagatttt aaataaactt tttaaatgaa taaattctca ggaaaaagga attataaata
    37681 cataataata cagcatagga gtagatggat atatgaacaa aataaataaa aatttcaaaa
    37741 atatttggat aatattagga gctgtatcga tttttaccat ggttataatt tttaataaaa
    37801 attgtaatgt taataaagag actcaaatag aagcttttac aattaagaat catgataaaa
    37861 aatttgtata tcctatggga aatataattg gagtaaaagc aaatacagat ggtgtattgg
    37921 tcttaggata tgaggaagag gatgtagact atattggagg catacaaatc ggtgataata
    37981 tagtaaaaat agataataaa aggataaaaa atagtcaaga tgtatcagag attttgaata
    38041 agattaaaaa aagtaaagtt gaagtgactt ttgagagaaa aaataagtat aaaacagaag
    38101 taatagagac taaaaaagaa aatggcaagt ataaacttgg attatgggta agagataaaa
    38161 tatctggaat tggaactatg actttttacg accctagtat ggaaaagttc aaagcaattg
    38221 gtcatgccat aaaagattcg gatactaatg aactattaaa gataaagcaa ggatatatat
    38281 ataagccaga acaattaaaa atagtaaaag ctagtaatga aaaagtaggt aaaataaaag
    38341 gagattttaa tgacagcaat ttaatgggta atttctcaaa taattcagag ttaggtataa
    38401 gtggtaatat tacagaaaac cataataaag agtttaatgt agcaaataaa gaaaagcaat
    38461 taatagaagt tggaagaccg caagatgtaa aaataggagg tgcagtaatt ctttttgagg
    38521 ataaaaacaa aaatataaca agctatgata taaaaataga aagtatagta tatgataaag
    38581 gaaattatag agatatggta ataaaagtag tagatgacaa gttattggaa tacacaggag
    38641 gtatcgtaca ggggatgagt ggagctccaa taatacaaaa taataaaatt attggtgcaa
    38701 taactcatgt ttttagagat aatccgaaaa aaggatatgg tatttttata gatgaaatga
    38761 taaaattgta ggtgaggcat taaaaaattt tattatttta tcaattatct aggaggaata
    38821 taattttgga gtgtcgaata tgctttagag tagataatta ggaagcaatt gtgtaaaaag
    38881 tttagttttc tgtaataaga agatgttttt taatgggggg atttttagtg gaaaaaatca
    38941 aaatagtttt agcagatgac aataaggatt tttgtcaggt attaaaagag tatttgtcta
    39001 atgaagatga tatcgatata ttaggcatag ctaaggatgg aattgaagca ttagacttag
    39061 taaaaaagac acaaccggac ttattaatac tagatgtaat aatgccacat ctagatggat
    39121 taggtgtaat tgaaaaattg aatactatgg atatacctaa aatgccaaaa ataatagtac
    39181 tatcagcagt aggtcaagat aagataactc aaagcgcaat aaatctagga gcagattact
    39241 acatagtaaa gccatttgat tttgttgtgt ttataaacag aattagagag ctagtttcta
    39301 atagagttac acaagttgag ccaaaaccta gaccagttca agagactcaa atgactagaa
    39361 gtgattttgt taagaatgta ggaaatatag agacagaaat cacaaatata atacatgaaa
    39421 taggagtacc agctcatata aaaggatatt tatatttaag agaagcaata aaaatggtta
    39481 ttgataatgt tgagctttta ggtgcagtaa caaaagagtt atatccaagt atagctaaaa
    39541 aattcaatac aacaccaagt agagttgaaa gagcaataag acatgcaata gaggttgcat
    39601 ggagtagagg aaaagttgac acaataaatc aattatttgg atatacggta cacaatacta
    39661 aaggaaaacc aactaattca gaatttatag caatgattgc tgataaatta agactagaac
    39721 atagtatggt taaataaaca agacataaaa agtaaggctt tttaattaag gcattggcta
    39781 taaatgcgta ttacaagcag cgaaacggta taaccactag ggttataccg tttcgctatt
    39841 ttaataaata taaaaatttt atttattatt tgcttactat atcaatataa taattttatt
    39901 atactatgga tatagtatgt gtctttacaa gttgtaaact gacagtggtt tattttttaa
    39961 tataaatatt gactttgatg caggtaaact ttgtattttt aagcgtatta tggaatatgt
    40021 taaataaaaa aatgatgaaa tatagtattg taaatgccaa agatgcaaaa caaacttaaa
    40081 acatttattt tattgttaag taatgctata atataatgtg attttaataa tgatagtgga
    40141 ggtttaaata tgagagtcga ggcccctata aaagtagatc gaaaaaccaa aaaacttgct
    40201 aaaagagttg aaagtgggga aatagcagtt ataaatcata tagacataga tgaagttgct
    40261 gcaaactctt tagtagaagc taaaataaaa cttgtcataa atgcggctcc ttctataagt
    40321 ggtaggtatc ccaataaagg tccagggata ttaactgaaa ataatatact aataattgat
    40381 aatgttggag aagagttatt tgaagaatta aaagaaggag aaactataga agttgtagat
    40441 ggaaagatat atagaaaagg aaaattttta ggtgcaggag aagttttaga caagtatgag
    40501 gtttcacacc aaataaaggc tgcctatgag aatttagctg tagaattgga tagatttata
    40561 gataatacta tagattatgc taaaaaagaa aaaggattta tacttggaga agtagaaatt
    40621 ccaaaagtga aaactaatta tgctaataaa catgtattga tagttgtaag aggtcaggac
    40681 tacaaagaag atttaagtac tatgctttct tatatagaag aggtaaagcc agtattggtt
    40741 ggtgttgatg gaggagcaga cgctttaatt gagtttggat atactccaga tgtgattgta
    40801 ggtgatatgg atagtgtaag tgatgaagct ttaaaaaagg ctagtgaaat agtagtacat
    40861 gcttatacag atggaagagc accaggtctt aaaagggttg aggaattagg cttagatgca
    40921 gttgtatttc ctgcaccagg aactagtgaa gatatagcta tgcttatcgc ttatgagtat
    40981 aaggctgagt taatagtagc agttggtaca cattcaaata tgattgattt tcttgaaaaa
    41041 ggaagaaaag gtatggcaag tactttttta gttagactaa aaataggttc aaagcttata
    41101 gatgctaaag gcgttaattt gttatacaga agtaaattaa aaataaagta catatgggca
    41161 ttaatagcaa cagcattatt tcctgtgttg gtagttgcat cattgtcacc aggagttcaa
    41221 cagttcatac aactaatgca attaaagttt agagtattat tacagatgta aattttagga
    41281 ggataaatat gcatattaat atgaaatatt atatagtcac tataggggct atatttatag
    41341 ctttgggtat aggcatgtta gtaggattta atttaaataa taatcaacaa ttaagtgaac
    41401 aacaagcaaa cataataaat gatttggatg ataagtttga tatcttaaaa gaaaaaaatg
    41461 ataaacttga cagtgactta gcaagtgtaa atagagatta tgaagaggca gttaatttta
    41521 taaataaaaa tgtagataag attttagctg gttcgctgaa tggtaaaagt ataggaataa
    41581 tatctgctaa tgaaaatgac gattatacaa aaaatataga agacataata aataaatcta
    41641 atggaagcat tgcatttaat ataatattaa aagaaaacat aacaaatcca gaaaagttaa
    41701 aggaaatgtc aactaaacta ggtacagatg taaaaaatgc aaatgatgca gttaattata
    41761 taattgacac tcttaaaaag gaagatgcaa gtgacatttt aacatatctt caagaactag
    41821 atgtaataaa gtttaatttt attggagata catatctaaa atatgattcc gttgtaatag
    41881 ctggtggaaa tgatgcaaaa gacagtacaa aacagtttga aaaaatagaa aaatttgtag
    41941 tttcaaaact taaatcagag aataaatatt tagtagaagt tcaaaataca ggagttaaaa
    42001 cttcttatgt agaactatat tctaaaaaca aagttgcaac tatagacaat attgatgaag
    42061 gtataggaag tatatctcta gctattcttc tacaacaagg taatatagtt ggtaattttg
    42121 gtagattgga tactgcaact tcattgttgc catctattaa atagaaataa ttttaaggag
    42181 agaaaaaatg gattcttata taagtataat aataccagct tataatgaag aaagtagaat
    42241 aaaatataca ttagaaagca tattggacat taagcaaata aatgaaataa tagttgtgga
    42301 tgatggttca attgacaata ctgctaaggt tgtatctgag ctagaaaatg aaaagattaa
    42361 attttttaag ttagataaaa atagaggtaa aggatatgct ttaaattatg gtatcaaatt
    42421 agcaatgaaa aatgcagata ttataggttt tctggatgga gatttaggaa gttctgctaa
    42481 agaagttgaa aaattaatag tacctatatt aaatggtgag gcggatgtta caatagccaa
    42541 gtttcctcct gcaaagagaa aaggaggttt gggatttgta aaaggtttag ctaaaaattc
    42601 tgtgtttgag atgactggtg ttgagttaga tgcaacttta tcaggtcaaa gaatatttaa
    42661 aagagaagtt ttagaaaagt ttgatgaaat accttttgga tatggagtag aagttggaat
    42721 gaccattgat atattaaagt atggatttaa aattaaagaa gtattagtaa atatgactca
    42781 taatgaaaca ggaagaaatt taaaaggttt tattcataga gggaaacagt attatcacat
    42841 aaaaaaggtt ttaggacaaa aaaagaaaga atggaggtaa tatcttagtg aaagattata
    42901 tactttatac cattttatta ttaactggat tatttggaac ctatgctgta attccactat
    42961 ttaaaaattt attgataaat ggaaatgtac ttagaccaaa ctataaaaaa gatatgatac
    43021 cagtaagtat gggaattgta tttttgccta tgattgtaat caatggaata atacttgctt
    43081 tctttactac agaatttaag gatttagcgt atatatttat gtttatgttt ggtatgatat
    43141 ccatgttttt tgcagggata ctagatgatg tcattggaaa tagagatgta agtggtttaa
    43201 aggggcattt taaaagttta tttaaaggaa gtcttacaac aggaggtttt aaagctttat
    43261 ttggtggatt tgtagggctt atagtttctg ttgctatatc aaaagacata attgatataa
    43321 tagtaaatac actaataata gctctatcaa ctaatttaat gaatcttttg gatttaagac
    43381 caggaagggc aataaaagca tatttattca taatggtaat tatattttta acattgacag
    43441 gatttgttca agttcttcca ttacttatag taccaaatgt acttgcatac tttaattatg
    43501 atttaaaagc aagggctatg atgggagata ctggttcaaa cgtccttgga atatctattg
    43561 gaatgctcat ttcttttggg tatccattta acattagatt aggatggtta atatttgtag
    43621 ttattatgca tatattcact gagaaatact cattaactaa gataatagaa aaaaataaac
    43681 tattaaattt tatagataaa ttgggaaggt agtattatga taagcaaaag agtggggatt
    43741 gttgaatcaa tagtaagtca aactgaaaca ctagatgata taagagtaaa tataaatgga
    43801 gaaatacaaa gggcatataa ttatcccaaa atatctggaa ctataaatat aggtgacgaa
    43861 gtggttttaa atacaacagc agtagaactg agcttaggta caggtggata ccattttgta
    43921 ataactaatt taaataatat agaatctact ttaactgaag gtggacatat aatgaaactt
    43981 agatatacgc ctcttcaaat aaaagtggat tctgttgagg aacaagaaag tatttatcat
    44041 gataaatttg cgaattttaa aggattagaa ggtctttctg ttgtagtagg gactcttcat
    44101 agtatgttaa ctccatttgc agcttcattt aaaagaaata atccaaataa aaaattagtg
    44161 tatataatga ctgatggagc atctcttcca atttatttaa gtaaaaatgt ggatacttta
    44221 aaagaaaaaa aattaataga tagtacaata actataggaa atgcgtttgg tggagattat
    44281 gaatgtataa atatatatac tgcattaatt acagcaaaag aaatactaaa agcggatgca
    44341 gtatttgtca gtatgggacc tggaattgct gggacaggaa caaaatatgg atttacaggg
    44401 attgaacaag gctctattct tgatgctgta aaaaaacttg aaggaagagc aattgcaatt
    44461 ccaagaatta gttttgctga caaacgagaa agacatcaag gtatttcaca tcatagtatg
    44521 actgtattta aagaaattgt aaatgtaaat gtagacatac caataactat atatgatgat
    44581 gaaaaattga actttataaa agagcaaatc aatttaaatg gtttagacaa aaagcataat
    44641 ataatttata tagataataa taaaacgaaa gaggatttag actattttaa tctaaaagta
    44701 aagagtatgg gaagaaatta tgaacaagat gaggcatttt tcaaagctgc aagcacagca
    44761 gcatattact taatggaggt ttaagatggt attagaagaa aaaactatta gtagtgatag
    44821 ggtttataca ggtaaagtaa ttactttaaa ggttgatact gttgaaattc cagggcaagg
    44881 atatcaaaaa agggagttag tagaagttgg tggagcagta ggaatagttg caatcacaga
    44941 tgataataaa gttgtgttag ttaagcaatt tagaaaacct atagaaaagc caatctttga
    45001 aattccagct ggtaaactag aaaaaaatga aagtccaaaa gaatgtgctg aaagagaatt
    45061 aaaagaagaa acagggtata gtgcaaaaaa tattaagcta atacataaat ttttcacttc
    45121 agcaggtttt tctaatgaga taatgtttgt atatttagca acaggtctta ctccaggaga
    45181 gaataattta gatgcagatg agtttttaga tgtctatgaa attgagcttg aagaagcata
    45241 taacatggta ttaaaaaatg acgttgaaga tgcaaaaaca tctattggat tattattagt
    45301 aaaagatatg tttaaaaatt aatatttata aaatgaataa ccctttgtcc taaagcatat
    45361 tattttataa aggacaaggg ggaattaaat tgagaagaac atatagaaaa aatgatttta
    45421 gagaattaaa tagacaaata attattatag gattgttgtt tatgatgtct attgttgttg
    45481 ggtcttacat aaataaaata ttgccaggtt ctagtaacaa tatattaaac aatataaatc
    45541 ctgctgtaga gtattataat ctaaatataa gcataaaaga tacagtgata caaaatttaa
    45601 aatcagatgc aatctttatg ggctcaatag ctctattaag tctatttgta gtaacaattc
    45661 cagcagtgtt ggtagctttt gtattaaaag ggatgtcaat tggttataca ataaatagtt
    45721 gtatattggc attaaaattt aaaagtataa aaatgatttt aataatatta tttaaaaatt
    45781 tgattattat tccatgtgca atcatattag cattaattag tttaagttat tttaaagaaa
    45841 tggtttatga atttaaaaag aaaaatagaa aaaatatgca atttttaatt aagaggtata
    45901 tactaaatat tataattata atagcactat cattggggtt gcaattaata ttaaatactg
    45961 caagtattgg tattattaag ttcctagcta aataaaggag tttataatgg atattataga
    46021 gggatatata gattacataa aagataaaaa aaaattatca gagaatacag tggcatcata
    46081 ctttatggat ataaaaaaat atatggaata tataaatcaa aaaagcatta aactagtaga
    46141 tatagtagaa aatgatatta taagttactt aataaagttg gaaaaagata atgtatcaat
    46201 agctacaata gcgaggatga tatcctctat aaaatctttt catgattatt tatttttaaa
    46261 tcatatatgt acaaataatc ctgcaaagga tataaaaaaa cctaaaataa aaaaagaaaa
    46321 tataaatata cttacagaag aagaaattga aagactatta aattttccaa agttaacaac
    46381 acctaaattg attagggaca aggctatttt tgaagtatta tatggtactg gtataaaagt
    46441 atctgaatta gtagagatga atatagagga tattgaccta gatattgatt atatatattg
    46501 taattcatgt tgtaaaaatc aaagagtgat accactttgt gatattacaa aactttactt
    46561 agaaaagtat ctaaaagaag caagacctaa aatggctgta gaaggtgaaa aatcattatt
    46621 cgtaagttca ttaggtcaaa ggtttacacg acaaggtctt tggaaagtca taaaaaaata
    46681 ttctaatcta gccaatatag ataaaaatat aaatcctaca atgcttagac attcatttgc
    46741 tattcatttg ttaaatgaag gtgctaacat tgctgttgta agtaaaattt taggaaatgt
    46801 taatttatct agtttgcaag tatatttaaa tcatatagat aaaaacgtga gaagagaaat
    46861 aaaggagaaa catcctagaa atgatgttga tgtagaatta caaaaagcag aagctaaata
    46921 gactatatag caaattttat aatttagaag gagcatattt atatgagcag agtaatttgg
    46981 attgtaattg atagtgttgg gataggagca ttgcctgatg ctgaaaaatt tggtgatagt
    47041 aaggatgtaa gtacccttgg aaatatattt aaggaatatc cagatattca gattcctaat
    47101 atgagaaatt taggtatagg aaacatagat ggtatagatt tttttgaaag tataaaagaa
    47161 ccaataggtt gttttggaaa gtgtaaggaa atgtctcagg gaaaagatac tactacaggt
    47221 cattgggaaa tgactggtat aatagttgac aaaccattta agacatttga acatggattc
    47281 tctaaggaga taatagaaga gtttgagaaa aaaactggaa gaaaagtagt aggaaataaa
    47341 ccagcttcag gaactgtaat aatagatgag tatggagaac atcaaataaa aactggagat
    47401 gtaatagtat atacatcagc tgatagtgta tttcagattg ctgctaatga agaagtaatt
    47461 cccctagaag aactctataa tatgtgcaaa atcgctaggg aaataatgat gggggataat
    47521 gcagtagcta gagtaattgc tagaccattc ataggtaaga aaaaaggtga gtttgtgagg
    47581 acttcaaata gaagagatta ttcactagac ccatttgaac caacagttct tgataatata
    47641 aaagaatcag gacttgatgt tttagcagtt ggaaaaatag aagatatttt taatggaaaa
    47701 ggaattacag atgctatcca cactaaaagc aatatggatg gagtggatga aactttaaat
    47761 tatatgaaac aagataataa aggtctaata tattcaaatc tcgttgattt tgattctaaa
    47821 tatggtcata ggagagaccc agaaggatat aagaaagctc ttgaagagtt tgatagtaga
    47881 cttcctgaaa taatggctaa tatgagagaa gatgatattt taataatcaa tgcagaccat
    47941 ggaaatgacc caacatataa aggtacagac catacaagag aatatatacc tgttatgatt
    48001 tatggcaata agattaaaaa aggttttaat ttaggagtaa aagatacttt tgctgatatt
    48061 ggagcaactg ttgcagatat actaaatgta aagttgccta aacatgggtc aagctttaaa
    48121 gaagatttat tttaaactat aaaatgataa aaacttagct taataggatg gagagattgg
    48181 aatgtttgaa aagatagcac aaagtagtaa atttataaat tctaaaagtg atataaaacc
    48241 taagattggt ttgatattag gttctggact aggtgattta gcaaatgata tagaagaccc
    48301 tgtcgcaatt aaatatagtg aaattccaaa cttccctgta tcaacagtag caggacatgc
    48361 tggacaactt gtaattggaa aacttgaagg aaaagaagtt attgctatgc aaggtagatt
    48421 tcattactat gaaggatatt ctcagaaaga agctactttt ccagtaaggg ttatgaaaga
    48481 attaggagtc gagattctta tagtaactaa cgctgctgga ggcgtaaata aagaatttaa
    48541 agcaggagat ttgatgctta taagagacca tataaacttt agtggaagta atccattagt
    48601 aggaaaaaat gatgacagat ttggtgctag atttccagat atgtcagatg catattcttc
    48661 taaatatgta gatgtagtta aaaactgcgc taaagaatgc aatatagatg tcaaagaagg
    48721 cgtttatatg ttttttagtg gtccaaacta tgaaacacca gcagaagtga gaatggcaca
    48781 aattttggga gctgatgctg taggtatgtc tactgttcca gaagtcatag tagcttctca
    48841 ctctaatata ggagttattg gtatatcttg tataacaaat atggctgctg gcatcttaaa
    48901 tcaaccacta agtcatgagg aagtaataga aactactcaa aaagttaaat cagaatttat
    48961 gaatttagtt aaaacaacgg ttaaaaattt ataagttaaa gcttattata gattttttga
    49021 ggaagtttat aataaaatag ttaatgttta atttgaaaag aattaataaa aagctgtctt
    49081 gatatagaaa gttatttcta ataaaggaca gtttttttat aatactacaa catttgaaag
    49141 tgttttaaag tttaatattt atttaaatta ttataggtta gaatggagat ttcaattatg
    49201 agaatgtatg atattataaa aaaaaagaga gataacctag agcttagtaa aaaagagata
    49261 aactacttta tagaaaacta ttcaaaggga gatatacctg actatcaagc ttctgcacta
    49321 ttaatgtcga tttatttaaa taagatgaat aaacaggaaa ctgtacatct tacagaagca
    49381 atgatgaact ctggagacat gataaaccta tctgagatag atggaataaa ggtagataag
    49441 catagtactg gtggtgttgg agataagact accatagctc ttataccttt ggttgcttca
    49501 tgtggagcac cagttgcaaa gatgtcaggt agaggtcttg gtcatactgg tggtactatt
    49561 gataaattgg agtctatacc aggtttttcg acagaaatgg agataagtaa atttattgat
    49621 tctgtaaata agtctaaaat agcagtttgt ggtcaaagtg caaaggtagc aattgcagat
    49681 aagaaaatat atgctcttag agatgttaca gcaactgttg ataatatatc attgatatca
    49741 tcaagtgtaa tgtctaagaa gttagcttca ggagctgatg caattgtgct agatgtaaaa
    49801 actggtgatg gagcatttat gaagacatta gaagagtctt ttgagttagc taaatctatg
    49861 gttgatatag gtactggtat gaatagagat acaataggga ttgtaacaga tatggatgaa
    49921 cctttaggtt ttgcagtggg aaactcttta gaagttatag aagcaattga gacattaaaa
    49981 ggaaatggac ctaaagacct tgttgagcta tgcgaagtat taggagcata tatgttggtt
    50041 ttatcaaagg tagcacatga ttttgaagat ggtgttgaaa aaataagaga atcaataaaa
    50101 tctggtactg ctatacaaaa actcaaagag tttatagaga atcaaggtgg taataaagat
    50161 gtagtagatg attattcttt attcaaaaaa tcaaagtata aatatccagt taaatcaact
    50221 aaatcaggtt atataagcaa aattaaagct gaagatgttg gtgtatcggc tatgattctt
    50281 ggagcaggta gagaaactaa agatgatatt ttagatttat cagcagggat aattttagaa
    50341 aagaaagtag gagattatgt aaatgaaggt gaagttttag cttacatgta ttataatgat
    50401 gaacaaaagc tttcattggc aaagggaaga tttattgatt cctactctat tgtagattca
    50461 aaaatagaaa aaaataaatt aatatatggt attgtaacta aagaagagat taaaaagttt
    50521 tagaaaattt tagaaaagtg attataaaag gcctaacatg tcaaaaataa tgttaggttt
    50581 tttatttttt gatagactat aaattatacc aaaaatatat attttaaaac attttttaca
    50641 atataaataa gtttattcta caagatgatt gaaaattaaa gtatctagtt ttataataga
    50701 aaatggataa atatacataa ggagtagatt atattatgaa ctttaaagaa aatagattga
    50761 aaatagcagt attaataatt gttattttga ttatcttagc aggtatattt gtgtttatac
    50821 aaataggtcc ttatgataaa aataacaaaa aagatgtaat tatcgacgtt ccaagtggag
    50881 catctgttgg aaaaatatct gacatattat atgaaaataa attaataaag aatgaactat
    50941 tatttaaact tttggtaaag gttagcaata aagctccgtc tataaaatca ggaacatact
    51001 tacttaatca atcgtattca aacaatgata taataagtct tttagtttca ggtaaaatat
    51061 atcaggatgg tataaaagtg actattccag agggagctac atctaaagaa attatagcaa
    51121 tgttagtaag taaaaattta ggagataaag ctacttttga aaatttaata aaaaaacctc
    51181 aagaatttta tgataaattt ccatatttga aggaagatgg aataacctct ttagaagggt
    51241 tcttgtatcc agaaacttat tattttaatt caaagaaaca atcagaagaa gatattttaa
    51301 gcgaaatgtt aaaagtattt gacagtaaat acacggacaa gtttaaaaag aaacaaaaag
    51361 aattaaatat gactcttcaa gaagtaatgg aaatggcatc aataattgag aaagaagctg
    51421 ttcttgacaa agacagacct ataatagcaa gtgtgtttta taatagactt aaggtaggta
    51481 tgcctcttca atcagatgct acaatacaat atatatttga agagagaaag aaaattgtaa
    51541 catatgatga tttaaaaatt gattcaccat ataatagtta taaaaataag ggattacctc
    51601 ctacaccaat atcaaatcct ggtataaaat ctattgaagc agcattatat ccagagaaaa
    51661 cagactattt atattttgta gctaagattg atggtggaaa taattatagt acaaactatc
    51721 aagaccattt aaaatacgtt aaagaatata aagaagcaag ggataaacaa tcaaaagata
    51781 caaaagcaac aaataaagaa aatacaaaaa aataaaccat gattataaaa agtctaacag
    51841 ggtaagaata atgttgggct tttttattga aaattgttat tcttagattt ataataaaga
    51901 aagtgtaaat atatataaca atatgaattt aaaaaataat aaattaatat aaaacttgaa
    51961 tatttattat tttagggagt gtttttatga gtaatatagt taatgatttg gttgaagatt
    52021 atataagagt gacattaaaa gaaaaagaag gatttttaaa agatttagaa atttatgcag
    52081 aggaaaatag tgttcctata atacataaag aagtttcaga tttattaaaa gtcttgttaa
    52141 aggttcaaaa accaaagaga attttagaag taggatgtgc aattggttat tcttctattt
    52201 tttttgcaac tattatagga aaagatgcag atataataac tgttgagaga aatgaaaaaa
    52261 tgatagaaaa agcaaaagaa aacataaaat tagctggatt tgacaataac ataactatac
    52321 tagaaggaga tgcagaagaa aaacttagtc aagtccaagg tgaatttgac cttatattta
    52381 tagatgcagc caaaggtcaa tataagctat tttttgattt agttatagat aaattaaaag
    52441 atgggggact tttagtatct gataatattt tgtataaagg tatggttgct catgatgatt
    52501 ttgttgtaag aagaaaaaag actatagtta aaagaatgag aaattattta gattatatat
    52561 gtaattgtga ctatttaagc acatcattgg taccaatagg tgatggtgta gcactaagtt
    52621 ataaagaaag taaaagaggt gatgtagatg gaattaaata aagtagaact tttagctcca
    52681 gctggtgatt tggagagatt gaaaatagct ataacatatg gagcagatgc cgtttatata
    52741 ggtggagaaa tttttggaat gaggtctgca gcgaagaatt ttagtaagga agatatggca
    52801 gagggagtag cttttgcaca tgaaagaggc aagaaagtat tcgtaacagt aaatataata
    52861 cctcataatg aagattttct acaattagaa gactatttgt tggaactaga agagatagga
    52921 atagatgcag ttataatagc tgacccagga gtgcttagtg tcattaaaaa agtaattccg
    52981 aatatggaaa tacatttaag tacacaagca aatacaacca attatctaag tgcaaacttc
    53041 tggtacgagc atggaataaa aagagttgta gtggcaagag aattatcttt tgatgaaata
    53101 tctgagataa gagcaaaaac acctttagat atggatatag aagcgtttat gcatggtgct
    53161 atgtgtattt cttattctgg cagatgttta ataagcaact atatgactgg aagagatgca
    53221 aacaaaggtt cttgtgctca atcttgtaga tggcaatatc atttggtgga agaaaaaaga
    53281 cctggtgagt attttccaat atacgaagat gaaaggggta cattcttctt taactcaaaa
    53341 gatttatgta tgatagagta tataccagag ttaatcaaat ctggtataac aagtttaaaa
    53401 atagaaggta gaatgaagac tgcatactat gtagctactg ttgtaagagc atacagaatg
    53461 gcaatagatg aattttacag agacccagaa aactggaagt tcaatccaat gtggatggaa
    53521 gaactaaaaa aaggtagtca tagacatttt acatcaggtt tttacttgaa taaaccaaca
    53581 acagaagacc aaaattatca atcagcatca tatgttagaa actatgattt tataggtata
    53641 gttagagaaa cagaagatga agatggtctt attgttgttg agcaaagaaa taaaatgtgt
    53701 gttggtgatg aaatagaagt tatgggacca tataaagaaa ctatgtttac taaaattgaa
    53761 gaaatgtaca atgaagaagg agaagctata gaatcagctc ctcatcctag acaaatagtg
    53821 aagttaaagc tatcagtaaa agttggtaaa gattatatgc ttagaaaagt tatagaagaa
    53881 aaggttgaag aataataaaa aattgataaa aatagtatta gccccttaga aattgtcaat
    53941 aatgaaatta tctaaggggt gatttcatgt caaaaaagaa gactccattt ttgaaaaaag
    54001 tgggaaagag aagctggtgt atatttacta taattttaat aatttatagt gttttaattt
    54061 ataggctagt tgatatacaa gtattaaaag gtgataaata caaacaaagt gttgaatcac
    54121 aaagcgttga gaaagtcgag ttaaatagtg gaagaggaat aatctatgat agaaacaaca
    54181 agaagcttac agatacaagt aaatctcagg tattaattgt tgaaaaagaa aaattaaata
    54241 ataactataa aattttggag cttattaaga aagctactaa gatgaatgat ttagatatat
    54301 ataaagctgt acaagagcaa ttgacacgcc ctataataca gattcagact aaaaatatcg
    54361 ataagagtat gaaaaaagaa cttgagaaaa atggaataat ggtagaagaa aaaactatga
    54421 ggtacgcaaa agatggttta ttatcacata caataggata tataaaagaa gatgataaat
    54481 caggtcaatc aggaattgaa aagagtatgg atagtgtact tagaaattca aatgaaaagt
    54541 atataagtgc ttttaaagct ggagatgcag gaaatgaaaa atctctaaac atactaaagg
    54601 gaagtgtaaa aactgttgat aataaggata aagatagaca tctaaaaact actattgatt
    54661 ataacattca aaaaaaatta gaacaaatac taaataaaga agaaaatcct acagcagcaa
    54721 taatctcgga agcatctaca ggtgaaattc ttgcaatgtg ctctagacct aattttgacc
    54781 aaaatgacat atcaaaaagt ttaaaaggaa aaaatggaga atttgaaaat agagttataa
    54841 aagcgacata tccaccaggg tctgtattta agatggtagt tttattttct gcacttgaaa
    54901 atggtgttat agatgagaac tatacttaca actgtacagg taagactaaa gttgggaata
    54961 ctaatgaaat actgcgatgt aataaaagag atggtcatgg tttccaaaac ttaagacaag
    55021 ctttttctaa ttcatgcaat cctgcatttt tagatatagc tatgaaactt ggaaaagaaa
    55081 agatactcaa atctgctgaa aaattacatt tatttgaaaa ggttgatatt ggtcttgatg
    55141 aagaaaaaat tagagaagct ccaaaaaaca tatcaataag aaatttagct ataggtcaag
    55201 aaaatataga atttacacca cttcaaataa atcaaatgac tcaaataata gctaataatg
    55261 gaacattcaa accactatac ttatataaaa gtcttgtgga caataatatg aatacaataa
    55321 aaacttataa gtcttcaaaa aaagaagaac ttatttctcc ttatgtgtgt acacaagtta
    55381 aagaatatat gaagtctgta tctaggattg gtacagctaa agacctaaaa gatattgaag
    55441 gtggttgtgg agttaaaact ggtacagctc aaagtagttt aaataaaaaa gctatagacc
    55501 atggatggat aacaggattt tatcctgaag aaagacctaa gtatgtaata actgtgttag
    55561 tagaaggaac tcaaaaagga aataaatctg caacacctat atttaaggaa atatgtgaaa
    55621 gtataaaata aattatgtac tataaaattt aaggatatat cgtaactttg attttagata
    55681 gaaaattttg tctaatgatg tacgatatat ccttttaaaa tatagtatta actttcttga
    55741 acaagctctt tttctagttt tttaagagct tttttttcga ttctagatac atatgacctt
    55801 gatatatcga gtttttgtgc aatttctctt tgtgtcttat agccataagg agttaaccca
    55861 tatcttaact ggacaatttc tctttctcta ggagtaagaa ttttgtttag ttgttcgtaa
    55921 agttttccaa cttgaacttt tagttcaact tcatcaagaa catagttagc ctctgtacca
    55981 agtatatcta aaagacttat ttcattacac actactcttt atatgttatt ggtattactg
    56041 gtcttcatgt aatttcaaat ggaccattaa ttcaaaagaa tctagttttt gttctttaga
    56101 cttataataa actgctttat caattacaga ttttaggagt ttattttttc caagggaatc
    56161 tgaatcatgg taaagtgata acacagtttt aatatcttct attattttag aattgtcttt
    56221 tttaacagta cttaatctat tttttactgt cttaattgaa tctttaattt cttcagttct
    56281 tgaacttata ttgttggacc tttcaataaa tgtatcttca tcatatattc ctcgttctag
    56341 taaatcatat aacttatttt tttgcttgcc taattctttt aattcagttt ctaagccctt
    56401 taagactcgt ttttgaaatt ctatattact atctttatta tttttatcta agtctatatc
    56461 agatgctttt aattgatatt tttttacagt gtcttctaaa gattttaaaa tggcagcttc
    56521 aataaattca aatcgagaac ttttattgca accaggatga taacaaatta tatagtcgtg
    56581 gtctgcatat ggtctatata ctaatggtct accacaattt ttgcaaatca ctattcctgc
    56641 aagtggattt tttatttgat taccatagct gacatgacca ttttttttga gtatattttg
    56701 agcttttttc catgttattt cacttattaa aggttcatgc tttccttttg cctcaatcca
    56761 ttcatcttta ggtcttagtt taactgtttt tattttattt ggatttttag attttttgta
    56821 gtcctttttt tgccactgaa tgtagccaca atatacctta ttttttatta tatttgtaat
    56881 tgcagaattg taccaattag cacctgtagc agttttaatg cctaagttat ttaggtattt
    56941 tgatatttta ctacaaccca tatcttcatt aatatataag tcaaagatag tcctaactac
    57001 atcagcatcc ttatttggta caagtattct ttcttttcta ccagttgtta cagcatcata
    57061 tccaaatgga gcagaggttc ctatgaaatt cccttcttca actgatttta ttctacctct
    57121 ttgcatcctt cttgatataa gttttaattc ttttcttgcc ataaatgctt caaattctga
    57181 atactcctca tcaaattcat ctgttaggtc gtatgttttt ctaggtgtga taattttggt
    57241 cttactttct ttgaatgttt ctaatatgat accttggtct ttcatgtctc cacgaccaag
    57301 tctgtctaag tccattacta agactgcatc atatttattt tcttcaactt cttttagaag
    57361 ttcaagcatt ttgggtctat gtattatact ttcaccagaa actaattctt cttttatctc
    57421 aattacatct aagttttgtt cttttgctag ttttagtagg gttgatttat gtctacttaa
    57481 agtttcaaat tcgccttgtt tttctgcctc ttcatcagca cgggattttc ttaagtatat
    57541 ggcaacactc ataataagta atcacactcc ttatgcacta ttatatagta aatcaataga
    57601 gtttaaaata tagaaaataa gcatgtcaaa agttaattta actttcaaca tacttatttt
    57661 ctataatatt aatgccttat aatcctttaa tatcatttag attagttttt gcatattcat
    57721 tatccgggtt aagttcaagc gccttattgt aagattctct agctttatta aattctgatt
    57781 tactcataaa aataacacct cttaaattgt aagcatcact agcgtctatt ttataagctt
    57841 cattattttt atctagatat tctaagtatt tatcaattga ctttaaagcc tcatcatatc
    57901 gttgtaactc tatataaata tatgattgtg tataatatgc aagtggattt ttatcatcaa
    57961 tttctatagc ttttttgata tcaatagcag ctttattata atccttatct tcatcttttt
    58021 ctgtttctga cctagcgatt ttgacataat tagagctaag agctctttta aagtctttat
    58081 gccataataa tttatattca ttatcttcga ttataaaata tctatcaaaa tttgcagtat
    58141 cttctttatt ttcagtgata tactttatag tatcagtttc ttttatttta acaagatttg
    58201 tgtactcttt attagaatat ttgtatttct ctactttatt ttcttcacca agtttataat
    58261 cttttagggt ttgaagttta aataaagtat cttgatattc ttcaaatttt tctagactga
    58321 cgctttcctt actgtcttta cttaataaat tatatgctac ttcgtagtct ttgattttta
    58381 tactatcaag gtacttttta gctacttctg tagcactttc ttttggagca catccaacca
    58441 ttgatatcat aattaaaaat gatactaata ttgctgttat ttttttactg attatcataa
    58501 tataatcccc cttatattgt ctctcattaa ttttatttta tcaccatatt ctaccaaagt
    58561 cattaattta agagtgatat ttttcattaa tattatatta agtaataata accttttaaa
    58621 tttatggtaa cattttcctg aaaagtatta tataatttag gtgaaaatat ttaagagaag
    58681 tagatattat gaaaattaaa aaattattaa caatagggtt atctttatct atatttattg
    58741 ctagttgccc tatatctgca aatgctcttg ataaaattga accaattaaa ggtgcagata
    58801 aatacgaaac tgctggtata attgcagaca aataaaacta tactacagct atattaatta
    58861 atgcagacag tacaatgtct gatggattaa gtgcaagtgg acttgcagga gctataaacg
    58921 ctccaattct tttgactaag aaaaataaca taccaaatgc tacacttaaa agattagaaa
    58981 aggcaaaaaa agtatatata attggaggag aaaactctat tgataaatat actgaaactg
    59041 ttctaaaagg caaaggaata gagattaaaa gacttcaagg tagtgataga attaagacaa
    59101 gctataatgt cgcaaaagaa ataaactcaa ttaacaaagt aaataaagtc atattgacta
    59161 atgcttttaa aggagagcct gatgcaatga gtgctgcacc tgtagcagtt agagataaag
    59221 cagctatagt attaactgat ggaaaaagtg tccatttaat acaactggtg tagaaagtta
    59281 tgtaataggt ggtacttcat caatgaatga caaaatagtt aaggatacta attcaactag
    59341 attaggtggg acagatagat atgatactaa caaaaagata ataaataaat tttatagtgg
    59401 agtaaaagaa ttttatatag caagtggtac tgatttagtg tatgctcttg ttggttctac
    59461 cattgctaaa aataatgcta ttgtgttagt tggtaatgat agtaataaaa gtgtattgaa
    59521 aagtacaact aaattaactg ctataggaaa tttgagtgat agtatattac agcagtgttt
    59581 aaatgtaaca aaaaatatag gcgattctaa tactggaaga gaatatacag tagaagatgc
    59641 tgctaatgta gtgaaaaaac tattaggtgt gaagaaattt tattacgaac ctaattattc
    59701 agaagatgaa gatttaactt acaatctata gagtggagtt catgtacaaa agattatcct
    59761 cccaacgatt cgaagggagg tgagttcatg gataactttt tgtttaatgt tttagctagt
    59821 ttaacagcta gtgtggtagt ttacttaatc agtaaactat tcaaaaaagc aaaaagccac
    59881 tctcgcacaa agagtgactt acgagttgaa tttaaattta tatttaaatc caaaaaataa
    59941 actctgttta tgatgaactc cactctaacg caaaatagat tgtagttctt cttgctttta
    60001 ttataccaca aaacattata aataaaactg ttgtttataa aaaaatgcaa agtaaaattt
    60061 tttataaaca atgataaaaa ttttattata gagctattaa cttatgaaat atctgtaaat
    60121 gagcagatat tt
//
LOCUS       DAEPKC010000011        55433 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.011, whole genome shotgun sequence.
ACCESSION   DAEPKC010000011 DAEPKC010000000
VERSION     DAEPKC010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 55433)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55433)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55433
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.011"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            68..141
                     /locus_tag="KR294_000788"
     tRNA            68..141
                     /locus_tag="KR294_000788"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:100..102,aa:Gly,seq:tcc)
     gene            150..266
                     /gene="rrf"
                     /locus_tag="KR294_000789"
     rRNA            150..266
                     /gene="rrf"
                     /locus_tag="KR294_000789"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            540..2558
                     /locus_tag="KR294_000790"
     CDS             540..2558
                     /locus_tag="KR294_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBH0238900.1"
                     /translation="MRRNTKLLTTGILSMAIVAPTMAFATESNAMENNADLNINLEKK
                     SIVLGSTSKVSVKFKEKPDADSITLKYKCYDMPLDTTLNYNQSTESYEGTINYNKDPE
                     YLNVWELQGITINSKNNPKTLNKQELEKMGLNLKDYNVTQECIIEDITSRKDVNKYLR
                     KTSAPITELTGSDRYETAVKISKEGWKNGSDKVVIINGDVSIDGIISTPLATTYNAPI
                     LLVEKNNVPNSVKSELKRLNPRDVIIIGDENAISKTTANQIKSTVNASQTRLKGSNRY
                     ETSLLIAKEIDKNHDVEKVYITNANGGEVDALTIAAKAGQDKQPIILTDKNSITDNTY
                     KWLKSEDLQNAYFIGGPQMISTNVINKVNDITKDNVTNNRVYGADRHETNANVIKKFY
                     TDDELEAVLVAKSDVLVDALAAGPLAANLKSPILITPKTYVSAYHKENLEAKSANKVY
                     KIGGGLTSKVMNSIASSLSKHNTTPTEPGNSGGKTVMIDPGHGGSDTGTTGKPLGGIK
                     EKDYTLNTSLATTEYLRSKGFNVIMTRDTDKTLSLGNRTALSNSLRPDLFTSIHYNAS
                     DTTGNGVEVFYKLKDKDGGTTKTVATNILNRILEKFNLKNRGAKTRTLSTDPTKDYLY
                     VLRNNDMPAVLVECAFLDNEKDMSLLNTSNKVKEMGTQIGKGIEDSLK"
     gene            3066..5078
                     /locus_tag="KR294_000791"
     CDS             3066..5078
                     /locus_tag="KR294_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBH0238901.1"
                     /translation="MRRNTKLLTTGILSMAIVAPTMAFATESNAMENNADLNINLEKK
                     SIVLGSKSKVSVKFKEKPDADSITLKYKCYDMPLDTTLNYNQSTGAYEGTINYNQDPE
                     YLNVWELQGITINSKNNPKTLNRQDLEKLGLNLKDYNVTQECIIEDITSRKDVNKYLR
                     KTSSPITELTGSDRYETAVKISKEGWKNGSDKVVIINGDVSIDGIISTPLATTYNAPI
                     LLVEKNNVPNSVKSELKRLNPKDIIIIGDENAISKTTANQIKSTVNASQTRLNGSNRY
                     ETSLLIAKEIDKNHDVEKIYITNANGGEVDALTIAAKAGQDKQPIILTDKDSITDNTY
                     KWLKSEDLQNAYFIGGPQMISTNVINKVNGITKDSVTNNRVYGADRHETNANVIKKFY
                     TDDELEAVLVAKSDVLVDALAAGPLAANLKSPILITPKTYVSAYHKDNLEAKSANKVY
                     KIGGGLTSKVMSSIASSLSKHNTTPTEPGNSGGKTVMIDPGHGGSAPGNSSGGMIEKD
                     YNLNTSLATTEYLRSKGFNVIMTRDTDKTLSLGNRTALSNSLKPDLFTSIHYNGSTNK
                     QGHGVEVFYKLKDKNGGTTKTVATNILNRILEKFKLTNRGIKTRVLPSDSTKDYLYVL
                     RSNDMPAVLVECAFLDNENDMSLINSSAKVKEMGTQIGKGIEDSLK"
     gene            5320..7233
                     /locus_tag="KR294_000792"
     CDS             5320..7233
                     /locus_tag="KR294_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0238902.1"
                     /translation="MEYLFEKSSLKEYGNEALDKYRELLDKTGNNSRCILLLVPNNNT
                     KIRYERALRLNYSEELKVTTYISFVKKELVKYWPLIIEKCDGISTKVVSPTFISNSLS
                     EYLIVQKVKEKRIQEGYFEDITGTNKSIANSIMTNINKSAFNLIDFDFIGEKIYSSKK
                     NKDSIYRFSYTQMDEIISYYINSLLSNSILDNALSIYLYNQYLLNDDFYLKNLFTEVR
                     YIIVDSLESSSNAEVDFITEALDNTLQSYIYFDYSRDYSVFNNVDIDYINEKIISKIK
                     PKEENIKKKEIRIEDLYLLPANIELNQSSQLYNEMLDLISEKVISLIEEDVSPRDIAI
                     ISPINNSILEHQIRDSLIEKNIDVFSTKKDKKAVDYPYGNALVVATCIFYGYLDFIKD
                     DEYLSFLETLLEINRIKAFKIFNETRHLSIDNIDEHSQYRDILQYIEEKKKSDIKIHE
                     FLTQFYIDKMLNLKEGKKNVGLCKKIIAESESFSESLSLLGMKKEKIFVEALKSTIND
                     YYSVVDIEELKSKDKIVITTPYSYISSNIDRSIQIWVDIGSNAWNMKIEKDISNLIVL
                     RKSFEEKKIYTNEMEEYYKKYYLYNTVYNLLLNAKKIYAFKSEYAINGYIQESILYSI
                     LLKISHKGDKNYD"
     gene            7226..9445
                     /locus_tag="KR294_000793"
     CDS             7226..9445
                     /locus_tag="KR294_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HBH0238903.1"
                     /translation="MININYREDQIPIINYDNGTMAVPAVPGAGKTFIITNLVAKLLL
                     EQKHKSGKILILTYMNSAVNNFKGRIRKILEENKIDDTNSYEVMTIHSLAVKIIKEKP
                     EVVMLSEDFNIADDLQKSIILNECISRFRFEGGERAFRWFLKEQKDERWKEITLEAWE
                     RGFFEFAGNAISELKYKGISPDKLEEILSRGHKGMLKIILPIYKLYDRKLKQNGLLDY
                     DDILILAEKTLSLDEGLRKKFQTRYKYIFEDECQDSNEIQGNIIKIISSENKNLVRVG
                     DINQSITGTFSSSDPKFFKEFINSADFCYRMDMSNRSSKDILDLANTLVKYVTKEFRQ
                     EECRHALEDMQIKTVPNGMGYKENPNPEHYNINVKWYESWKIEIEQTARYVKGIKNKY
                     PDKSIGILVPFNEQVTQVAKELRENNLTFEELGPNSLNKRKVINNIAYIIDFMLHCDD
                     VEKLIVVLNKVFIDTDNEEEIKYFLEELKNYSTEEIIYNFEFSKLDNDLIEFKEESDI
                     YLSFKRGIDIIKQILEYPIIRLDLLVLFIGKKLSLEKEDKAVLDYISFYIKYLVSENI
                     NMDLEDVYNLLFDVKNRVFNHIIDVVYEINGYEPEPGSITLCNYHKSKGMEWDCVFLL
                     GLVEYNFPDNINQKFQSDKWYLKEKYKNPMAIIKSEVEAILKGSISTDYAHKTKIDSI
                     NEKIRLLYVGITRAKEMLVLSGSAYRDESDIGNKRKEQKPCIYLSRLNQHIIEKRSN"
     gene            9554..10384
                     /locus_tag="KR294_000794"
     CDS             9554..10384
                     /locus_tag="KR294_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HBH0238904.1"
                     /translation="MNDKLKYFSYSQNSINTYKSCPLKFKYKYIDRINWKNDDVGSRE
                     YYETLKTGRDFHLICERYFSNIPLGIYFNEDDKNSKKFLKWMENIKKVVPIEKGKTYL
                     PEYEVRMTLNGDIIQAKYDLVVIGNNNIEIWDWKTESKKIDYKHVENRIQTIVYMFLA
                     KEVIPKVLKMDINVKDINMRYYQPEFDDLPITILYDEEKHEANRNKIQNYISMIKNTN
                     YEEHTYEDNLYNDIEKVYNKEERMCYRNKKHCKYCEFNKLCNGKEIDYSILEAEIYGT
                     "
     gene            10374..13841
                     /gene="addB"
                     /locus_tag="KR294_000795"
     CDS             10374..13841
                     /gene="addB"
                     /locus_tag="KR294_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddB"
                     /protein_id="HBH0238905.1"
                     /translation="MGLRFVLGRSGSGKSTYILDEIKKEAQKNETTSIILLVPEQYTF
                     EAENRVSKLFLGKEKDKYLRVRVLSFKTLSNIVFSQVGGLTDVNINSSGKAMMVYRAI
                     EDVSEELNVFSKSKSQSGFVSSITDMISEMKQYNISPEMLENISGELDNETLSLKLKD
                     ISKIYNSFEGKLHENYVDAQDMLTSLASKIELSSYLDGACVYIDEFTGFTPNQYNVIK
                     SILNKSKSVNISLTVDDINYIGYSKSDMFSRTKFTYSKLTQLCNEEGIKILPQVNLNT
                     GVIKRFEKVKELQHLERFYNAYPYKIYSNQTENIKIKEFNNLYSEVEEIAREIVHLVR
                     DKNVRYRDITIATRDLNRYDFLVHSIFNEYNIPNFIDKKREAKSNPIVILIISALEMK
                     NRRYGYETMFRYLKSGLIGIDNDDINLLENYVLANGIKGKKWFDEKWDYRITQSLSGQ
                     ESEFELELKEKINEIKNRVLEPIVILQEKLRGKNRVKEICRYIYEFLLDINMPETIES
                     LIINFKDKGELDVANQYSQVWDIVVDILDQMVELMGDEIISLEKFIKLITLGFDEYEL
                     GLVPPSIDQVLVSSVDRMKNPDTKYLYLVGTTDGVFPLITKDSGILSDNDRESLGNKG
                     IEVDIDSKTRSFEEQFLVYKALTSTSKNLTITYPISDHEGKTLRPSIIISRLKKIFPN
                     IENKSYLVEENKSTDKDILKKITVKSPTFNELINVIKNYDSDGYNTEEINSIWLDIYR
                     YYLKDEIYSSITKKVIKGLSYTNQVHKIEEKKIRSLYKSNSLSISRLEKYAECPFAYF
                     IQYGLKAKKRKEYSFTPPDLGTFIHNILDRFSKELLQDNLTWRDIDEKYIELKIGIIV
                     DEIILKIPGYILNSSERYKYLAYRLKNMLTTAITIISQQIKQGSFEPIDYEVKFGNNG
                     KYPPIKMVLENGQEVSLIGQIDRVDEFEEGENKYIRIIDYKSGNKSISLTEIYYGLQL
                     QLLVYLDAILESAKDEDININPAAILYCRINNPIAKFNEDKDDEEIQEAILKELRMKG
                     LVVKDSHIVKEMDKSLIDGERKNSLVIPVGLTKDGNVGKSTSAISYEDFKLLRKYVRH
                     AIKDLCEEMLSGEIRIAPYKHKDGTSCDFCDYSAICQFDSTIKDNKYKNLNNKSNEEI
                     IKMMKGDVN"
     gene            13841..17668
                     /gene="addA"
                     /locus_tag="KR294_000796"
     CDS             13841..17668
                     /gene="addA"
                     /locus_tag="KR294_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HBH0238906.1"
                     /translation="MSSPKWTKEQLEVIESRECNLLVAAAAGSGKTAVLVERIIQMIT
                     SRENPIDIDKLLVVTFTNAAASEMRERIGDAIGKALDENPENKHLQNQLVLLNKSSIT
                     TIHSFCLDVIKSNFHRINLDPNFRIGDQTECAILKQEAIEEVFEDLYEERDEGFLNLV
                     ESYAERGGDKEVQDIILGIYSFAMASPEPKKWLIDSAERFNIDENFDFSQSIWARAIL
                     DTVKIEINGLCLNMERALKEVESIEELETFAEKLSVEYKKIADISQACNKSWDEAYKK
                     MASMSFENYVKGVKRISKDAPSYIKESKEKAKTIRDKTKKSLESIVSATFNKDNDSIR
                     EEIKYLYNIVKPISSVVLRFEEEYSNKKREKGIIDFNDIEHFALNILTDVDEKGNIVP
                     SDIAVGYRNKFYEIFIDEYQDSNLVQEVLLKAVANTETPNRFMVGDVKQSIYRFRQAK
                     PELFLQKYNNYNDKKGSSHRKIMLYKNFRSREEVVDAVNYIFENIMNENIGEIEYTEK
                     ERLNLGANFNVDTDEKSIIGGATEIHLIQKDNKLDDDIINDKDDRINNKENEIEEEEK
                     LDNIQLEARMVGNIIKDLMKVNEDGKIQKVYDKGIDGYRPVEFRDIVILLRATSAWAP
                     VFADELMNMDIPTYADVGVGYFDTIEIKTILSLLQIIDNPMQDIPLISVLKSPIFGFT
                     PEDLIDIRVQSKDKIFYEVLKSTAEYDGFTDSQNENESEFIPSEECINKSKDFLIKLK
                     EFKEKSMYMSTDEFIWYLYTRTGYYAYVGALPGGSQRQANLKVLFERAKQFEETSLKG
                     IFNFVNFIEKLKKSSSDMGSAKTLGENANVVRIMSIHKSKGLEFPVVICSAMGKNFNT
                     QDFKKSILYHHNLGYGPQFVDYERRISFPSIAKEALKSKINIENLSEEMRVLYVAFTR
                     AKEKLIITGSTRNIQDSIKRWSNGIESLDTISQYEILKGKNFLDWIMPCVLRHRDLSN
                     LLEEVGLDAVFNVEHNSKWYGKLWNKSDILVEKKSDEEKESIEEILEKIDVDNPDSDY
                     YSEIEEKLNYIYPYEFSTRKPATISVTEIKKIQNNYEEELINTIFEQKVILKKPLFIQ
                     NEEEREKISGTERGTIVHLVMEVLDLKNVSSVNDIKSQIRGFVSKGIITEKQASIVNP
                     YKIYKFFASNIGKRMLNAEIINREKSIYAQVNMKDIYIYEKLINNDDKKLYDNESVML
                     RGIVDAYFEEDNQIVLVDYKTDFVNEENINQIIEKYKKQLDLYADIIETLTGKSVKEK
                     CIYLFGVDEAVCY"
     gene            17714..18925
                     /locus_tag="KR294_000797"
     CDS             17714..18925
                     /locus_tag="KR294_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HBH0238907.1"
                     /translation="MRFIHTSDWHLGKSLEGHSRIEEQAKFCEEFIKIVESNEIDMVI
                     IAGDVYDTSNPPAQAEKLFYQTVSRLANNGQRCVLIISGNHDNPERLSAITPLAHEQG
                     ILIYGYPLSATIEAKYKGFEITYATQGCTKLNINGENIVVATLPYPSEKRLNEVFSSE
                     DEFEKQKNYSEKVGDIFRSLEENFRSDTINIAVSHIFVIGGESTESERPIQLGGSFLV
                     ERKDLPEKAQYTALGHLHKQQKASERLNAYYSGSPLQYSKDERAYTKGAYIVDIKAGE
                     KPIIEDVYFNNYKPIEVFKCNGIEEALDICEQNQDREIWSYFEINTDEIISQNEIKKM
                     KELLKDIIEIKPIITSCYEQESVDIKEKSMAELFREFYSFSKGVEPKGELMDLFLDII
                     SEEGESADETN"
     gene            18912..22439
                     /locus_tag="KR294_000798"
     CDS             18912..22439
                     /locus_tag="KR294_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBH0238908.1"
                     /translation="MRPIRLELTGLNSYIDKQVIDFEKLIERGLFGIFGTTGSGKSTI
                     LDAITIAMYGNISRNTKEYINSVCDKAIISYEFEIGSKNTRRRYIVDRTIARSKTGTK
                     TSNARLIEVLNDNTQNVLADKVVEVNEKVAQVVGLTANDFTRSVVLPQDKFNEFLRLS
                     RADRRDMLERIFNLEKYGRSLGEKVKKRKNIQLQNLKDLKSKLSQYDGITEEVYNNIN
                     QELIELKNLEKDKNNALDLAQKSYEESKTVYEEQLKLEKNELRKNELDLKNSEIKEKI
                     ALVENDSNAKKVDPYISSVQNLEKKIDEDSFAVSNLEKKLAILNQELEVTKNRYEKIN
                     KIKNEEIPKLSEEKIRLQQAIKLEEELVLLDRELKELKESGINLNKTKVELEKVKQVS
                     ESRKDAVTKSIKEVEGKIDKVNISAELKQKIFLAYEYEKDYNNVLEEKNQKLNKLEEI
                     LKETENINLKVRYIDKDKNDVNRNLENLSLHLDVLLKKCPGKSADLLLKSEYVTELRN
                     KANNTKENEIKKSSIQDELKIILESKFNTEREVNLLNEKLENNRKNRDDLEKELEELK
                     YLNLASELRRELKENMPCPVCGSKHHENHDITKYDENISFVKEKLEKLEKEKISIRNN
                     IEELNAKVSGYLSIEKMKTKELEDVKGKLGGIPSSQLLKKLDEEQRKLALLKSNIQEW
                     EKEKESTENKVTLAKEEKNKIEKEELKIRESLNNYKKLTRDLNIEIEGLENKCKKLKQ
                     EYLGLKTITKVSNLLSKVKEIRENEKELELLSTGHSNLLKNRDSLDIKIRENESKLHE
                     IEIELIKARELYVEKKLSRDNKYKEVISITKGDLAKNLLHNVEENICKILEQEESSKK
                     KLEEQRLEYEKNIAEKHNIDGRLKTAKEQYKDQKSTLNKLLAENKFESIYAVKRALLD
                     TDAVKKLIEEILEHEEEQKLLSFKIKSSKEKLNGRSIKKEYFEQLKDEIYNLKVEIGN
                     ISKDIGANQNQLITLKDSLDKINDFNKQLKVVEHNVDLLEELDKCVQGNKFVEYVSTN
                     QLKYIALEASKRLDGITKGRYALEIDSTLNFVMRDNFNGGERRSIDTLSGGETFLTSL
                     SLALALSSQIQLKGSAPLEFFFLDEGFGSLDSELLEIVIESLERLHSNNLSVGIISHV
                     EELKNRVPVKLLVSSSEAGIGSKVKIEYS"
     gene            22570..23823
                     /locus_tag="KR294_000799"
     CDS             22570..23823
                     /locus_tag="KR294_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HBH0238909.1"
                     /translation="MLESPNNLIQIIFLIVLLIGSAFFSASETALMSLSKIRIRYMQD
                     EGVKGAKLVSSLIENPNKLLSSILVGNNVVNIAATSISTSLFIGLMGEKGVALATAVM
                     TVLVLIFGEITPKTIAANNSEKVSLLVSKPIKAIIFILRPIVWIFNIITNIIFKLFGI
                     TNKGAKSFITEEELKTMVNVSHEEGVLEMEEREIINNVFEFGDMQAKNAMVQRIDMVA
                     IDMEDSYDEIIQVFKTEKLSRMPVYEETIDDIVGILNIKDIIFLSDEEIESFDIKNYM
                     REPFFTYEFKKITQLLEEMKLEKSQMAIVVDEYGGTSGLLTIEDLVEVIVGDIEDEYD
                     EEEDEIQVIKEDEYIVDGSTKIGDVNELIGVNLESEEFDSIGGFIIGHLSRLPEENEV
                     IEVDNIRFCIESIEKNRIKKIRIYT"
     gene            23972..25024
                     /gene="ytvI"
                     /locus_tag="KR294_000800"
     CDS             23972..25024
                     /gene="ytvI"
                     /locus_tag="KR294_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation integral membrane protein YtvI"
                     /protein_id="HBH0238910.1"
                     /translation="MSILENNFLYKLKNNTIFFCIYTLLFIFIYKAFPYIAPFFLGAI
                     IALMINPISQKLENKFHINKGISTLVLSFLAVAIVSTVTTIIVINSMKELMGFLNNIS
                     ANPEDISNTIMYFLNKINDFMKSFQEIANFDVEQLVNKFSGEVMQITKNLLTSILGLA
                     TSIPYIIIFIITLFIATYFIAKDLDKIENSFYNMFTVDVRKKVKNVKKEAGLSLVGYI
                     RAYTILMAITFFAIWGSFALFGLKYGLIVGFVGALMDLIPFLGIITIYLPVIVYYFLI
                     KNYFIAISMTVIFFVLSLIREILEPKLVSVNVGLNPLATLAAIFIGIQVKGIIGVIFC
                     LGLVCMHDILKKVDIF"
     gene            25114..26340
                     /gene="pepT"
                     /locus_tag="KR294_000801"
     CDS             25114..26340
                     /gene="pepT"
                     /locus_tag="KR294_000801"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HBH0238911.1"
                     /translation="MKQKVVERFLKYVSFDTTSNSQCENCPSSEGQRVLAKYIVEELK
                     TMGVDDVSLDENSYIMATLKGNTDGVDTIGFISHLDTIEDVSGKDIKPKIIENYDGKD
                     IVLNEALNVITYVKDSPELEEFKGDDLIVTDGTTLLGSDDKAGIAEIVTAIEYLINHP
                     EIKHGDIKIGFTPDEEIGRGADLFDVEKFGAKYAYTLDGGIVGELECENFNAANATIT
                     IHGRNVHPGSAKNKMVNAIHIAAEISEMFPADERPETTEGYEGFWHLNSIGGNVENVS
                     MAYIIRDHCKEKFENRKSIMIENIEKINKKYDNRVELDLKDSYYNMKEKIEPVMFIVD
                     IAKEAMEELGIKPRLVPVRGGTDGARLSFNGLPCPNIFTGGLNFHGKNECIPVSSMEK
                     ATKLIVRIAEKYAERV"
     gene            26547..27599
                     /locus_tag="KR294_000802"
     CDS             26547..27599
                     /locus_tag="KR294_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp18"
                     /protein_id="HBH0238912.1"
                     /translation="MKIKSKKIIAFALSLGIMLPSCVYADNISKNQNAQVDMNNYLQG
                     RKSPKEEKLIGEDRFDTAIKISQSGWNNGSERVFLVNSNSLPDALASTPLASKLDAPI
                     LLTNKNSIPYNVTEEIKRLNPAEVILIGSEGAISSSVKESLEDMEVLVSRIGGADREE
                     TSLLLTRQLDDTGDLGVSKVAVVNGYNGLADATSISSPAASDNTAIIYTGKDSIRSEA
                     KNFITQNSTKTYIVGGEYSISKKLEGQLVNSERLAGTDRKDTNAKVLEKFYGKSSKVN
                     NMYFAKDGSGREADLVDGLAAGVLASKTKSPVVLASGSLSSAQKSFIKKVKADKFVQV
                     GGGKNSKPYAEALALQ"
     gene            complement(28017..28586)
                     /gene="yfcE"
                     /locus_tag="KR294_000803"
     CDS             complement(28017..28586)
                     /gene="yfcE"
                     /locus_tag="KR294_000803"
                     /EC_number="3.1.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphodiesterase"
                     /protein_id="HBH0238913.1"
                     /translation="MKIGIMSDTHGSLLYFEKALNVLSDCDVLLHGGDVLYHGPRNDI
                     PEGYNPKKFIETLNKLENIVIVKGNCDADVDQMVIEHPIQSPYVMSQFGEIRIILNHG
                     YIESEEEIIDKAKKMGGDILVLGHTHVKKLYMDDNLIVINPGSTSIPKDGSHSVAIID
                     IIKTDDEDELELDINLIDINTGNIININD"
     gene            complement(28611..29411)
                     /locus_tag="KR294_000804"
     CDS             complement(28611..29411)
                     /locus_tag="KR294_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+)/NADH kinase"
                     /protein_id="HBH0238914.1"
                     /translation="MKRIITINTNQLNKSLETKELLTRKLINAGFEVYSDIYPDTELI
                     ISIGGDGSFLRTVRDFDFPEIPIMGINTGHLGFFPDILPDKIDSFIEAYTKKDYIIQE
                     MSLLNAEVYTTTSGSNMLAVNEVVIRGDKSRTIHLNLSLDNKHIQNFSGDGMIISTST
                     GSTAYNYSAGGSIVDINLELMQITPLHPINTNAYRCFTSSIICSNESVIKIAPEYRFE
                     DSVLIVVDGVEHRFRQIENIKVSISDAKIKLLRMSNYEFWHRVSEKFL"
     gene            29546..30406
                     /locus_tag="KR294_000805"
     CDS             29546..30406
                     /locus_tag="KR294_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0238915.1"
                     /translation="MFSIRNITKKLGKFKLNNINLELKEGDIVGIIGPNGSGKTTLIK
                     IIMGIIDADEGEIELCNETIENSPISFKNNIGFVYDSLQFYPHLKVKEFRKIVSLFYK
                     NFDRERFDEYLNKFDIEENMHIENLSKGQSEKLMLSSALSHNAKLLILDEPTAGIDPI
                     VRTEIMQYLQDFVKNGSSSVIISTHNTDNLIKIADYLVFINRGNQIFTVKKELIEQEY
                     KIIRANKAELEAIKESIVGVKEYKYYNEALVKVGDSLKVKSLLIEIDKHKVKNPTIEE
                     LMYYYVNEVR"
     gene            30406..31092
                     /locus_tag="KR294_000806"
     CDS             30406..31092
                     /locus_tag="KR294_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 transporter permease"
                     /protein_id="HBH0238916.1"
                     /translation="MFNLIRKDLIIGISSDGIRNLKYILLFFVFYFFLNSISYYTVSI
                     VVSYLIFINTFECDYENDSRIFIRSMPVSIEDIVYSKYLLGVGLIISVTIIVSLLSKL
                     TSLVFFRNMVLNDVFFSVNIFLAILTILLPLIFKFGYGKMKVCGFIVSILIYFVYGSL
                     LKMISMIVYQVKHFNYSKVGGVYLSNYVTDIANTKYINLYSMTFLTIIIFIISMYFSI
                     KISKKNKFNY"
     gene            31144..31686
                     /locus_tag="KR294_000807"
     CDS             31144..31686
                     /locus_tag="KR294_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0238917.1"
                     /translation="MKKFIKVSFFILGIFTLFIAINKLVYRDMVSVKDYEINHLEEIV
                     FDFDSRRSRDVGTIVRFKISNNSKYSYKLNSAKMKFENCVENKKGMNKCSAYVNVDLF
                     NEKNSITERTLKYGIKPNNQGYVDFVIPKGLNFDYRYFNESGMSVEYKGEYIVNIPMA
                     KGLYLVVGKNNDTWNANIME"
     gene            31765..32232
                     /locus_tag="KR294_000808"
     CDS             31765..32232
                     /locus_tag="KR294_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaK/EbsC family protein"
                     /protein_id="HBH0238918.1"
                     /translation="MSISNVREYFKQFGKEDSILEFEQSSATVELAAEAAGVIPARIA
                     KTLSFKIGDDAILIVTAGDAKIDNKKYKAEFNCKAKMLTPEEVLEFTGHAIGGVCPFG
                     LKNSIKVYLDDSMKRFDTVFPACGSSNSAIELTCEEMEKFSKCEKWVDVCKNW"
     gene            32941..34077
                     /locus_tag="KR294_000809"
     CDS             32941..34077
                     /locus_tag="KR294_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="HBH0238919.1"
                     /translation="MDLNSKKYQMLKELYVSFAENEVKPLATELDEEERFPYETVEKM
                     AKAGMMGIPYPKEYGGEGGDTVGYIMAVEELSRVCGTTGVILSAHTSLGSWPIYQYGN
                     EEQKQKFLRPLASGEKLGAFGLTEPNAGTDASGQQTTAVLDGDEYILNGSKIFITNAI
                     AGDIYVVMAMTDKSKGNKGISAFIVEKGTPGFSFGVKEKKMGIRGSATSELIFEDCRI
                     PKENLLGKEGQGFKIAMSTLDGGRIGIAAQALGLAQGALDETVKYVKERVQFGRPLSK
                     FQNTQFQLADMEVKVQAARHLVYQAAINKDLGKPYGVEAAMAKLFAAETAMEVTTKAV
                     QLHGGYGYTRDYPVERMMRDAKITEIYEGTSEVQRMVISGKLLK"
     gene            34136..34918
                     /locus_tag="KR294_000810"
     CDS             34136..34918
                     /locus_tag="KR294_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009524639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HBH0238920.1"
                     /translation="MNIVVCIKQVPDTTEVKLDPNTGTLIRDGVPSIINPDDKAGLEE
                     AIKLKEEMGAHVTVITMGPPQADMALKEALAMGADRGILLTDRAFAGADTWATSSALA
                     GALKNIDFDIIIAGRQAIDGDTAQVGPQIAEHLNLPSITYAEEIKTEGEYVLVKRQFE
                     DCCHDLKVKMPCLITTLKDMNTPRYMKVGRIYDAFENDVVETWTVKDIEVDPSNLGLK
                     GSPTSVFKSFTKSVKPAGTIYNEDAKTSAGIIIDKLKEKYII"
     gene            34937..35947
                     /locus_tag="KR294_000811"
     CDS             34937..35947
                     /locus_tag="KR294_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HBH0238921.1"
                     /translation="MGNVLVVIEQRENVIQTVSLELLGKATEIAKDYDTKVSALLLGS
                     KVEGLIDTLAHYGADEVIVVDDEALAVYTTEPYTKAAYEAIKAADPIVVLFGATSIGR
                     DLAPRVSARIHTGLTADCTGLAVAEDTKLLLMTRPAFGGNIMATIVCKDFRPQMSTVR
                     PGVMKKNEPDETKEAVINRFKVEFNDADKLVQVVQVIKEAKKQVKIEDAKILVSAGRG
                     MGGKENLDILYELAEIIGGEVSGSRATIDAGWLDKARQVGQTGKTVRPDLYIACGISG
                     AIQHIAGMEDAEFIVAINKNPEAPIFKYADVGIVGDVHKVLPELISQLSVAKEKGEVL
                     AN"
     gene            35966..36763
                     /locus_tag="KR294_000812"
     CDS             35966..36763
                     /locus_tag="KR294_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="HBH0238922.1"
                     /translation="MSTSDVKVYENVAVEVDGNICTVKMNRPKALNAINSKTLEELYE
                     VFVDINNDETIDVVILTGEGKAFVAGADIAYMKDLDAVAAKDFSILGAKAFGEIENSK
                     KVVIAAVNGFALGGGCELAMACDIRIASAKAKFGQPEVTLGITPGYGGTQRLTRLVGM
                     AKAKELIFTGQVIKADEAEKIGLVNRVVEPDILIEEVEKLAKIIAKNAQLAVRYSKEA
                     IQLGAQTDINTGIDIESNLFGLCFSTKDQKEGMSAFVEKREANFIKG"
     gene            36861..37706
                     /locus_tag="KR294_000813"
     CDS             36861..37706
                     /locus_tag="KR294_000813"
                     /EC_number="1.1.1.157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxybutyryl-CoA dehydrogenase"
                     /protein_id="HBH0238923.1"
                     /translation="MKLAVIGSGTMGSGIVQTFASCGHDVCLKSRTQGAIDKCLALLD
                     KNLTKLVTKGKMDEATKAEILSHVSSTTNYEDLKDMDLIIEASVEDMNIKKDVFKLLD
                     ELCKEDTILATNTSSLSITEIASSTKRPDKVIGMHFFNPVPMMKLVEVISGQLTSKVT
                     FDTVFELSKSINKVPVDVSESPGFVVNRILIPMINEAVGIYADGVASKEEIDEAMKLG
                     ANHPMGPLALGDLIGLDVVLAIMNVLYTEFGDTKYRPHPLLAKMVRANQLGRKTKIGF
                     YDYNK"
     gene            37793..38968
                     /locus_tag="KR294_000814"
     CDS             37793..38968
                     /locus_tag="KR294_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000786547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HBH0238924.1"
                     /translation="MREVVIASAARTAVGSFGGAFKSVSAVELGVTAAKEAIKRANIT
                     PDMIDESLLGGVLTAGLGQNIARQIALGAGIPVEKPAMTINIVCGSGLRSVSMASQLI
                     ALGDADIMLVGGAENMSMSPYLVPSARYGARMGDAAFVDSMIKDGLSDIFNNYHMGIT
                     AENIAEQWNITREEQDELALASQNKAEKAQAEGKFDEEIVPVVIKGRKGDTVVDKDEY
                     IKPGTTMEKLAKLRPAFKKDGTVTAGNASGINDGAAMLVVMAKEKAEELGIEPLATIV
                     SYGTAGVDPKIMGYGPVPATKKALEAANMTIEDIDLVEANEAFAAQSVAVIRDLNIDM
                     NKVNVNGGAIAIGHPIGCSGARILTTLLYEMKRRDAKTGLATLCIGGGMGTTLIVKR"
     gene            39164..40066
                     /locus_tag="KR294_000815"
     CDS             39164..40066
                     /locus_tag="KR294_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBH0238925.1"
                     /translation="MFKKENQRYNLISYTNEEEMTLKEVLLDKLNFSVRSLSKMKREK
                     SVLVNGVYKKPSLKVYSGDLIEVKIDEEKANFEPQDLNLQIIYDDFDIIMVNKPPFMV
                     VHPTKSHYDKTIANGISYYIDNQKENVKIRFVNRLDMNTSGLVIVAKNAYAHHTLSTA
                     MSENKVEKKYITVVDGIIKENEGTIDEPIYRPTEDSIKRIIDERGQSSVTHYKVIERL
                     ENATVLEVSLETGRTHQIRVHMAHIGHGIIGDELYGYVDEDLINRQALHAYKLEFEQP
                     RTKEKLKFKADIPEDMKELISKLR"
     gene            40080..41084
                     /locus_tag="KR294_000816"
     CDS             40080..41084
                     /locus_tag="KR294_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HBH0238926.1"
                     /translation="MIIHKFIIHVLDKNSDVPILNDFEGKVNQEVDGFFQKAIKRIAK
                     DEDLRKGVFKDYNDNLIKNCCEQIIYDESTFLKNSKEIASYLFDVMKINAALESCDLA
                     ICLYTIKDEKSVAILKLDYKKLYTHSIEFVDDKFNIQMVSNEIGIPETLRQKQGALIS
                     LSGINDEFHLRLLDKDAEKEGSESKFVTEFLNAKKIDDDKYKTKVFKNTAENWITNAL
                     SNDIKQAEDVRSILNYTLKEKHEVDINDFVDNSIKDDELKDSFKEHMEEKGLDESFSI
                     DKKWVEKKLKKRSIKTDNGFDIKGNLTDFEDPMKYTVKQNQDGTIDIIIKNVTFYEEK
                     "
     gene            complement(41228..41455)
                     /gene="acpP"
                     /locus_tag="KR294_000817"
     CDS             complement(41228..41455)
                     /gene="acpP"
                     /locus_tag="KR294_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HBH0238927.1"
                     /translation="MFEKIKEIIAEQLGVDNLDEITMEASLMDDLEADSLDAVEIIMA
                     LEDEFGIEIPDEEAENFKCIGDICKYIEENK"
     gene            41627..42052
                     /locus_tag="KR294_000818"
     CDS             41627..42052
                     /locus_tag="KR294_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0238928.1"
                     /translation="MKYVGLLLTSVGMFLLIAVNFYYNSITLDMQRIEDYVMETNLIL
                     EDVAEKESYVSNEKEDYISRLMHVKKGIENSKTSFLIERYKEYKIKSIESLIYTISEE
                     KKDYLDEVDRYNKLGEKEINKLINKNFLEVTYLSITTYI"
     gene            42100..42306
                     /locus_tag="KR294_000819"
     CDS             42100..42306
                     /locus_tag="KR294_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0238929.1"
                     /translation="MTKLEDNMERFFGGCEGFFGNKMLIIIVIVFLLLCTDILEDLLC
                     DDNIWIWVILIVLLLFNFDDGCCC"
     gene            42488..42667
                     /locus_tag="KR294_000820"
     CDS             42488..42667
                     /locus_tag="KR294_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0238930.1"
                     /translation="MLDRFFGEEGCFGGGGWWIIVLFFLFLAFGDSWAEFDIMAWIPF
                     LIVLLILCCCGGCLE"
     gene            42701..42901
                     /locus_tag="KR294_000821"
     CDS             42701..42901
                     /locus_tag="KR294_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0238931.1"
                     /translation="MLDRFFGEEGCFGGGGWWIIVLFFLFLAFEDCWRDIDIMSWIPF
                     LILLLITCSCGGFFDGEVGCGC"
     gene            43154..44170
                     /gene="ccpA"
                     /locus_tag="KR294_000822"
     CDS             43154..44170
                     /gene="ccpA"
                     /locus_tag="KR294_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator CcpA"
                     /protein_id="HBH0238932.1"
                     /translation="MKGNITIKDVAKQAGVSISTVSRVINDSKPVTDEVKQKVLEVIK
                     ETGYIPNPLARSLVTKKSQLIGVIVPEVSDSFVNEVLNGIEEVAKMYDYDILLANTYS
                     DKEQELKSINLLRAKQVEGIVMISWIVEQEHINYIQNCGIPATYISKTARNYDIYTVS
                     TSNEEATFDMTEHLIKKGHEKIAFIMTSKDDTVLEMERLAGYEKALSNNNIELDKSLI
                     KYGGTDYESGYNSMKELLDDGIIPHAAFVTGDEAAIGAINAICDAGYKVPEDISVAGF
                     NDVKIARMYRPKLTTVYQPLYDMGAVAIRMVIKLINKELIENKKIELPYRIVDRESVT
                     ERKK"
     gene            complement(44293..44691)
                     /locus_tag="KR294_000823"
     CDS             complement(44293..44691)
                     /locus_tag="KR294_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0238933.1"
                     /translation="MKKLDTESLEKMAKQKNIDKDKIEKMADSYKGKSENELMEELIK
                     IGKNLDGRDEVVSKFKAFLDENQRKKLDNIMEKISDAENQRDTKPAKTKKAKPTKGKS
                     NSPAPKNTPGSQQKKSKSLFKKTKKSNPHE"
     gene            44903..45808
                     /locus_tag="KR294_000824"
     CDS             44903..45808
                     /locus_tag="KR294_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0238934.1"
                     /translation="MNNLLFLIGVIALSNGNISIFDDKNKSKGNNRVRKNKKNANDKL
                     SQSTHGNLRFDANDIKRGLRLMDLSEEDLEMGMEIITRTKKYMSRDERKILIKIESVL
                     DLVRGIKKLNNIDMVDTEDETDFFRKMDSDDKKNMMIKEIIDVFPEKRKNSVEKAIGM
                     KKKIDLFAELFLPDDFGEGGFSLSSLANINNLGSMNNLKLLGSLLRGDDSNNDDEDNN
                     DELNYEDEELDCEDKELDDDELTDEGEMEDNEDELVEDKNTGYENIENDEDIVYDEEL
                     YNINEQESEYNYNEKNTKTRAKKKR"
     gene            45923..46103
                     /gene="ssrS"
                     /locus_tag="KR294_000825"
     ncRNA           45923..46103
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="KR294_000825"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            46286..47503
                     /gene="cdeC"
                     /locus_tag="KR294_000826"
     CDS             46286..47503
                     /gene="cdeC"
                     /locus_tag="KR294_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exosporium morphogenetic protein CdeC"
                     /protein_id="HBH0238935.1"
                     /translation="MQDYKKNKRRMMNQPMSTMNEEEVYTDEINSEDMRGFKKSHHHN
                     GCNTDNKCECHDDCNPCNPCNPCKPNPCNPCKPNPCDDNCGCHDNCKCDCEPCEMDSD
                     ECFENKCGPECCNPISPRNFSVSNAVPFAIEANRIFDTMQFQTFTDATGPNGEPLTFE
                     TEVVEVFGSVPSAGQASVTIEKICLSNDGIVIDTGMTTLEDFDLDPLGDIVGRNCETT
                     FEFAVCGERNSECCRQGKGKSVAYKQRGLTVAVRNLVLELRGRCGCTEFVALAFPAVR
                     AGGGCKRRVDYVEFTFNTLSAPICLPADGRAVTLRQEYQTNLTVDCIGKSILKLECNE
                     CCEPFYELIIPNDIDLVLCLQETVSTLISEQIVVLASPNPIQPRLVDTFSKVCDFSQC
                     GPNHGSGKPSCHR"
     gene            complement(47603..48925)
                     /locus_tag="KR294_000827"
     CDS             complement(47603..48925)
                     /locus_tag="KR294_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBH0238936.1"
                     /translation="MKVPYLVLSTVILFISNFIVRIFGFLYKIFLSRALGETGLGIYH
                     MIFNFLMICLAVTTTGIPTALSCLVAKRKALNDRHNTNALFISTLYISFFVALIISIV
                     ASFNSSFLSLKFLKDAKLNLFILAVCPAIVIITLSNVLRGYYYGIKNVKIPAIGQIIE
                     QIGKILFVFLLVMYINNKSMNCYIALLGISIGELSNIIFMLICLWRDSSFDNRYIISI
                     KDFYNSSMETLKMSIPITCNRMSNILLQSISSMMIPSRLALSGMTYQQSLSMYGIVSG
                     MVMPFIFLPFTVGSALIVNLIPTISQEMALRKRKSVIKKIKYSILLTLFVGILSSIFF
                     YFFGKDLCILVFKNTLAGEYLKAMFLVPLFMSLNQTLSGILHSIRKELASSINTITGM
                     LIQLIALYVFLPIPGLNIYAYIYTMTIVSIFTCLLHTIVLFKSLKSIR"
     gene            complement(48976..49770)
                     /locus_tag="KR294_000828"
     CDS             complement(48976..49770)
                     /locus_tag="KR294_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase HisJ family protein"
                     /protein_id="HBH0238937.1"
                     /translation="MFYDYHMHSSFSTDGKSTMEEMVKKSIELGLEEICFTDHVDYDV
                     YADDSFSIVYEDYFKSLETLQSKYKDKISIKKGIEFGVQTQLMDTYKKEAHQYPLDFI
                     ICSIHAIDTMDLYLGNYFKDKTQHEVYENYYLYLYNIVKNYKDYSVLGHLDLIKRYAP
                     YDTILDDRLFSDIIEETLKQAIYDGKGIEINTSCYRYNLPDLTPSKYILQMYKDLGGE
                     IITTGSDSHHISQVACEFDYIYSLLKNMGFKYVSKFNKLKPEFIKL"
     gene            49880..51325
                     /locus_tag="KR294_000829"
     CDS             49880..51325
                     /locus_tag="KR294_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBH0238938.1"
                     /translation="MEKYRIDLNEKKSTKYIQIFNHIKELIINKELVEHEKLPPIRKL
                     SNFLQVNNTTIVKVYELLENEGYVYKIIGSGTFVSSLNSYKSGIDNRKNKIIVQREDL
                     IHFDNGNPSNDMFPIDSFKNAVNMALSKDGSSIFEYDEGLGSEELREKMVEYLSDGNI
                     KTTKENIQIISGAQQGIDIVCKGLISYSDVVFMEEPSYNGAIEVFKSRGAKIISIPML
                     DDGIDIGILKLKLEKIKPRLIYIMPNFQNPTGISYSTYKKKKLIELAEEHDFYIIEDD
                     FISDFVFESKDNRTIRSYDDKNRVVYIKSFSKILMPGLRIGIVEMPNELLKKVLWAKY
                     SSDISTPGLIQKSMYYYMNNFDWKNYLSHIEKIYTDKYKLAKNLINDKLSGKLKVRKS
                     CGGINFFLELPRGYTSQAFTNFMLNKGVSMLPGTYFFDNLVDDRFFRINIARPSMEEL
                     EKGISIISDNIDEFFCEYKNKLDIKSNKLFY"
     gene            51354..51563
                     /locus_tag="KR294_000830"
     CDS             51354..51563
                     /locus_tag="KR294_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 domain-containing protein"
                     /protein_id="HBH0238939.1"
                     /translation="MFDKKKLDRINELAKKNKEGILSADEIKEREILRKEYLENFRAH
                     FRSRLDSVKVVSPEEYEQYMKNNKN"
     gene            51583..52977
                     /locus_tag="KR294_000831"
     CDS             51583..52977
                     /locus_tag="KR294_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HBH0238940.1"
                     /translation="MNLKYEFKNAWDFERKENTIEQIMQYSSNYMEFLSKSKTERLSV
                     KEIIKLAKENNYISIDEAMEKGSISCGDKIYVINKEKAVALFVIGKNYIEKGMKIIGS
                     HIDSPRLDLKPNPLYQESNLGFFKTHYYGGIKKYQWTAIPLALHGIVILNDGTKVDIS
                     IGEEDSDPVFCVTDLLIHLAGDQMQKKLSEGISGEALNILIGNMPLEDEEKEPITANI
                     LKILNEKYNIVEEDLLSAEIEVVPAGKARDLGLDRSMVLGYGHDDRVCSYAAVKAILE
                     TEQPEFTSVALCVDKEEIGSKGNTGMHSKFFENTVAELIALEGDYCDIKVRRALANSK
                     VLSADVSAGYDPNFGEAYEKRNSAYMGNGVVLTKYTGSRGKSGCNDANAEFMSEVKRI
                     FNKGNVVWQTAELGKVDQGGGGTIAHILANQGAEVIDCGVGVLNMHAPHEIVSKVDIY
                     EMYKGYKAFFNINL"
     gene            53217..53402
                     /locus_tag="KR294_000832"
                     /pseudo
     CDS             53217..53402
                     /locus_tag="KR294_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896033.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
     gene            complement(53511..54677)
                     /locus_tag="KR294_000833"
     CDS             complement(53511..54677)
                     /locus_tag="KR294_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017752472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBH0238941.1"
                     /translation="MKGGVRKRGKKWYYYFDAGIVDGKRKKVERVGGNTKKEAEKSLR
                     DAINEYENAGIVFDETNMSLSDYLNFWYKEYVLLNCKYNTQESYRNLIENHIEPRLGK
                     CKLKSINPAIIQEFLNNKSKETYTQNGEEKHYTKGVLKAIYVVLNAALKSAVYPYKLI
                     KENPVQYASIPKNVLKVKNESDNKTITLDEFNKILEIYPKNTNIYIPLLIGFHTGMRK
                     GEILGLCWDNVDLDNNIIKVRKNLIKRKVSEFELASPKTKTSIRDIKIGDTLSRILKE
                     EKLNQKKQKIKIGKWYKETEYDWVCRKKDGSFVNHNNIDAAIRTINKKLNINFNFHCL
                     RHTHATLLLENGANVKYIQQRLGHSQLSTTMDTYSHVTSKMESETIDILEGILQ"
     gene            complement(54815..55021)
                     /locus_tag="KR294_000834"
     CDS             complement(54815..55021)
                     /locus_tag="KR294_000834"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0238942.1"
                     /translation="MNLSFNKKKKFELSKEELELIENWLGNKYAGDMTIPAIVDFSLE
                     TDIEYEKIVVYLAEKVLESRDKKH"
     gene            complement(55080..55304)
                     /locus_tag="KR294_000835"
                     /pseudo
     CDS             complement(55080..55304)
                     /locus_tag="KR294_000835"
                     /inference="COORDINATES: protein motif:HMM:NF024835.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
BASE COUNT        22474 a         5876 c         9666 g        17417 t
ORIGIN      
        1 gatatatatg tagtttttag agtgctaact ctaaaaaatt agttttacta atttataaaa
       61 atttaatgcg ggtgtagctc aatggtagag ttctggcctt ccaagccagc tgtgagggtt
      121 cgatcccctt cacccgctcc aaaagattat gtggttacaa tagcagagag gatacacctg
      181 ttcccattcc gaacacagaa gttaagctct ctagcgctga tggtacttgg tgggaaactg
      241 cctgggagag taggacgtag ccacgtaatc tttttttgtt gtattaaatt taataaacct
      301 acaattgtta tatgttttta tttgtctttt atagattttt ttggcaataa atgatatagt
      361 gaagataatt aaatatattc aatatattta atttttttat tttttgtttt tataattttt
      421 ttagaagttt attttttatg tacttattta taattttggg taaaaacact ttgatataat
      481 ttcaaaaatt aaaaggttaa aaaacaaagt agaaatttat gttaaataag gagattaata
      541 tgagaagaaa tacaaaatta ttaacaacag ggattctttc aatggcaatc gtcgcaccta
      601 caatggcatt tgctactgaa tctaatgcta tggaaaataa cgctgattta aatataaact
      661 tagagaaaaa aagtatcgtt ttaggtagta cctcaaaagt cagtgttaag tttaaagaaa
      721 aaccagatgc agatagcatt acattaaagt ataaatgcta tgatatgcca ttggatacaa
      781 ctttaaacta caatcaatca actgagtcat atgaaggaac tatcaattat aataaagacc
      841 cagaatatct aaatgtttgg gaactacaag ggataacaat aaacagcaaa aataatccta
      901 aaactttaaa caaacaagaa ctagaaaaga tgggattaaa tttaaaagac tataatgtaa
      961 cacaggaatg tataattgaa gatataactt ctagaaaaga tgtaaataaa tatttaagaa
     1021 aaacttctgc acctattaca gaacttacag gaagtgatag atacgaaaca gcagttaaaa
     1081 taagtaaaga aggctggaaa aatggttcag ataaggtagt tataataaat ggggatgtaa
     1141 gtatagatgg cattatatca actccactag caactacata taatgcgcca atacttttgg
     1201 ttgaaaaaaa caatgtacct aatagtgtaa aatcagaatt aaagcgttta aatcctaggg
     1261 atgtaattat aattggagat gagaatgcta tttctaaaac tactgctaat caaattaaat
     1321 cgactgtaaa tgctagtcaa acacgtctaa agggctctaa tagatatgag acatctttat
     1381 tgatagcaaa ggaaatagat aaaaatcatg atgtggaaaa agtgtacata acaaatgcta
     1441 atggcggaga agtggatgca cttactatag cagcaaaagc aggtcaagac aagcaaccaa
     1501 ttatattaac tgataaaaat agtattacag acaacacata taaatggtta aagagtgagg
     1561 atttacaaaa tgcttatttt ataggtggcc ctcaaatgat atcaacaaat gttataaata
     1621 aggtaaatga tataactaaa gataatgtta ctaataatag agtatatgga gcagatagac
     1681 acgaaacaaa tgcaaacgta ataaaaaaat tctatacaga tgatgagcta gaggctgttt
     1741 tagtagctaa atcagatgta cttgttgatg ctttagcagc aggtccattg gctgccaact
     1801 taaaatctcc aatacttata acaccaaaga cgtatgtatc tgcataccat aaagaaaact
     1861 tagaagctaa atcggctaat aaggtatata aaataggagg aggattgact tctaaggtaa
     1921 tgaactctat agcatcatca ttatctaaac acaatacgac tccaacagaa ccaggaaata
     1981 gtgggggtaa gacagttatg attgacccag gacatggtgg ttcggacact ggaacaacag
     2041 gtaaaccatt agggggtatt aaagaaaaag actatacatt aaatacttca cttgcgacaa
     2101 ctgaatattt acgttcaaag ggattcaatg taataatgac aagagataca gataagactt
     2161 tatctcttgg aaatagaact gctttatcta actctttgag accagattta tttacgagta
     2221 tacactataa tgcatctgat acaactggga atggtgtaga agtattttat aagcttaaag
     2281 ataaagatgg aggaactact aagactgtag ctacaaatat attaaataga atcttagaga
     2341 aatttaatct aaaaaataga ggtgcaaaaa caagaacact atcaactgac cctacaaaag
     2401 attatttata tgttttaaga aataatgata tgccagctgt acttgtagaa tgtgcatttt
     2461 tggataatga gaaagatatg agtttactta atacatcaaa taaagtaaaa gaaatgggta
     2521 cacaaatagg taaaggcata gaagattcat taaaatagtc tacaatgaga gcatagaaaa
     2581 atttaaaata aattaatcta taattttaaa tttaaactaa agctataaga taagaatgta
     2641 attataatag taataaagac tgtatataca ttgtgcatat aaatgcgaaa tgaggtatat
     2701 acagtctttt tataattaat tgtaaaatga tttatgttat atgaaaaatt tacatatatt
     2761 aaggctacag ttaattgtca agagctggag tattcatttg taatacacaa tataagctta
     2821 attactatat tttattgtgt gttttttgtg gatttttatg tcaataaatg atatagtata
     2881 gataattaaa tgtattaaat atatttaatt tttttatttt ttgagtttta taagtttatt
     2941 tttatatatt acttatatat tacttatata ttatttatat tttgggttag atacactttg
     3001 acatattttc aaaagttaaa agattaaaaa taaagtagaa atttatgtta agtaaggaga
     3061 ttaatatgag aagaaataca aaattattaa caacagggat tctttcaatg gcaatcgtcg
     3121 cacctacaat ggcatttgct actgaatcta atgctatgga aaataacgct gatttaaata
     3181 taaacttaga gaaaaaaagt atcgttttag gtagcaaatc aaaagttagt gtcaaattta
     3241 aagaaaaacc agatgcagat agcattacat taaagtataa atgctatgac atgccattgg
     3301 atacaactct aaattacaat caatcaactg gggcatatga aggaactatc aattataacc
     3361 aagacccaga atatctaaat gtttgggaac tacaagggat aacaataaac agcaaaaata
     3421 atcctaaaac tttaaacaga caagacctag aaaagctggg attaaattta aaagactata
     3481 atgtaacaca ggaatgtata attgaagaca taacttctag aaaagatgta aataaatatt
     3541 tgagaaaaac ttcttcacct attacagaac ttacaggaag tgatagatat gaaacagcag
     3601 ttaaaataag taaagagggt tggaaaaatg gttcagataa agtagttata ataaatgggg
     3661 atgtaagtat agatggcatt atatcaactc cactggcaac cacatataat gctccaatac
     3721 ttttggttga aaaaaacaat gtgcctaata gtgtaaaatc agaattaaag cgcctaaacc
     3781 ctaaagatat aattataatt ggagatgaga atgctatttc taaaactact gctaatcaaa
     3841 ttaaatcaac tgtaaatgct agtcaaacac gtttaaatgg ttctaataga tatgagacat
     3901 ctttattgat agcaaaggaa atagataaaa atcatgatgt ggaaaaaata tacataacaa
     3961 atgctaatgg cggagaagtg gatgcactta ctatagcagc aaaagcaggt caagacaagc
     4021 aaccaattat attaactgat aaagatagta ttacagacaa tacatataaa tggttaaaga
     4081 gtgaggattt acaaaatgct tattttatag gtggtcctca aatgatatca acaaatgtta
     4141 taaataaggt aaatggaata actaaggata gtgttactaa taatagagta tacggagcag
     4201 atagacacga aacaaatgca aacgtaataa aaaaattcta tacagatgat gagttagagg
     4261 ctgttttagt agctaaatca gatgtacttg ttgatgcttt agcagcaggt ccattggctg
     4321 cgaacttaaa atctccaata cttataacac caaagacgta tgtatctgca taccataaag
     4381 ataatttaga agctaaatca gctaataaag tatacaaaat aggaggagga ttgacttcta
     4441 aggtaatgag ctctatagca tcatcattat ctaaacacaa tacgactcca acagaaccag
     4501 gaaatagtgg gggcaagaca gttatgattg acccagggca tggtggttca gcacctggaa
     4561 attcatctgg aggaatgatt gaaaaagatt acaatttaaa tacttcactt gcaacaactg
     4621 aatatttacg ttcaaaggga ttcaatgtaa taatgacaag agacacagat aagactttat
     4681 ctcttggaaa tagaactgct ctatctaatt cattgaaacc agatttattt acaagtatac
     4741 attataatgg ctcaactaat aaacaaggtc atggtgtaga agtattttat aagcttaaag
     4801 ataaaaatgg agggactact aaaactgtag ctaccaatat attaaataga attttagaga
     4861 aatttaaact tacaaataga ggtataaaaa caagagtact tcctagtgat tctacaaaag
     4921 attatttata cgttttaaga agtaatgata tgccagctgt acttgtagaa tgtgcatttt
     4981 tggataatga aaatgatatg agtttaataa actcatctgc aaaagtaaaa gaaatgggta
     5041 cacaaatagg taaaggaata gaagattcat taaaataaat ggaaataaaa atatttaaaa
     5101 acttaatgta aatttatagt tgtaaattta tactaaagtc aaaaaatgaa atataagtgt
     5161 atcaatagta agactgtatg tacatttgca catgtgaatg caagtatata tacagtcttt
     5221 ttttgtagtt aaatgcaata atttgattgt gttttgtaaa atacacaata tgatataatt
     5281 agataatata cacttaattt aattgaggaa ggtgattata tggaatattt atttgaaaaa
     5341 agtagtttaa aagaatatgg aaatgaagct ttagataaat atagagaatt attagataaa
     5401 actggtaata attcaaggtg tattcttttg ttagtaccaa acaataacac aaagatacga
     5461 tatgaaaggg ctctaagatt aaattatagt gaagaactga aagtaacaac atatataagt
     5521 tttgtgaaga aagaattagt taaatactgg ccactaataa tagaaaaatg tgatggaata
     5581 agtacaaagg ttgtatctcc aacatttata tcaaatagtt taagtgaata tttaatagtg
     5641 caaaaagtta aggaaaaaag gatacaagaa ggatattttg aagatattac aggaaccaat
     5701 aaatccatag caaatagtat aatgactaac ataaataagt ctgcatttaa tttaattgat
     5761 tttgatttta ttggagaaaa aatatattca tcaaagaaaa ataaagatag tatatataga
     5821 ttttcataca ctcaaatgga tgaaattata tcatattata taaattcctt actatcaaat
     5881 tcaattttag ataatgcatt aagcatatat ttatacaatc aatacctact taatgatgat
     5941 ttttatttaa aaaacttatt tacagaagtg agatatataa ttgtggatag ccttgaaagc
     6001 tcaagtaatg cagaagttga ttttataaca gaagcattgg ataatacatt acaaagttat
     6061 atatattttg attatagtag ggattattct gtatttaata atgtggatat agactatata
     6121 aatgagaaaa taatatcaaa aattaagcct aaagaagaaa atattaaaaa gaaggagatt
     6181 agaatagaag atttatactt attacctgca aatatagaat taaatcaatc aagtcaatta
     6241 tataatgaaa tgttagattt aataagtgaa aaagttatat ctcttataga agaagatgta
     6301 tctccaagag atatagcaat tatatctcct ataaacaata gtatattgga gcatcaaatt
     6361 agagattctt tgatagaaaa aaatatagat gtttttagta ctaagaagga taaaaaagct
     6421 gtggattatc catatgggaa tgcattggta gtggctacat gtatattcta tggatattta
     6481 gattttataa aagatgatga atacttaagc tttttagaaa ctcttttaga aataaatagg
     6541 ataaaagcat ttaagatttt taatgaaaca agacatttaa gtattgataa tatagatgaa
     6601 catagtcagt atcgtgatat tttacagtat attgaagaaa aaaagaagag tgatataaaa
     6661 atacatgaat ttttaactca attttacata gataaaatgt taaatttaaa agaaggtaaa
     6721 aagaatgttg ggttatgtaa aaagataata gctgaaagtg agtcttttag tgaaagttta
     6781 agtctacttg ggatgaaaaa agaaaagata tttgtagaag ctttaaaaag tacaataaac
     6841 gattattact ctgttgtcga tatagaagag ttgaaatcca aagacaaaat agtaataact
     6901 actccttatt catatatatc atcaaatata gatagaagta tacaaatatg ggtagatata
     6961 ggaagtaatg cttggaatat gaaaatagaa aaagatataa gtaatttaat tgtacttaga
     7021 aaatcttttg aagaaaaaaa gatttataca aatgaaatgg aagaatatta taaaaaatat
     7081 tatctataca atacagtata taatttgtta ttaaatgcaa agaaaatcta tgcatttaaa
     7141 agtgaatatg cgattaatgg ttatatccaa gagagtatat tatatagtat acttttaaaa
     7201 atctcacata aaggagataa aaattatgat taatataaat tatagagaag accagatacc
     7261 aataataaat tacgataatg gtactatggc agtaccagca gtaccaggtg ctggaaaaac
     7321 atttataata acaaatttag tagctaaact attacttgaa cagaaacata agagtggtaa
     7381 aatattaatt cttacatata tgaatagtgc tgtaaataat tttaaaggta gaataagaaa
     7441 gattcttgaa gagaataaaa tagatgatac taattcgtat gaagtaatga ctatacacag
     7501 tttggctgta aaaataataa aggaaaagcc agaagttgta atgttaagtg aggattttaa
     7561 catagctgac gatttgcaaa aaagtattat attaaatgaa tgtataagta gatttagatt
     7621 tgaaggtgga gaaagagctt ttagatggtt tttaaaggag caaaaagatg aacgctggaa
     7681 agaaataact cttgaagcct gggaaagagg tttttttgaa tttgcaggaa atgcaataag
     7741 tgaacttaag tataagggaa tttctccaga taaacttgaa gaaatattgt caagaggaca
     7801 caaaggaatg cttaaaatta ttttaccaat atataaattg tatgatagaa aattaaagca
     7861 aaatggattg ctagattatg atgatatatt aattttagca gaaaaaactt taagcttaga
     7921 cgaagggctt agaaagaagt ttcaaactag atacaaatat atatttgaag atgagtgtca
     7981 ggactcaaat gaaattcaag gtaatataat aaaaattata tctagcgaaa ataaaaacct
     8041 agttagagtt ggagatataa atcagagtat aacaggaaca ttttcatcat cagaccctaa
     8101 attttttaaa gaatttataa atagtgcaga tttctgttat aggatggata tgtcaaatcg
     8161 aagttcaaaa gatatacttg atttagcaaa cactcttgtc aagtatgtta caaaggaatt
     8221 tagacaagaa gaatgtagac atgctcttga agatatgcaa ataaaaactg tgccaaatgg
     8281 aatgggatat aaagaaaacc ctaatccaga acattataat ataaatgtaa agtggtatga
     8341 gagttggaaa attgaaatag agcaaactgc tagatacgtt aagggtataa aaaataaata
     8401 tccagataaa agtataggta tattggttcc atttaatgaa caagtgacac aagttgctaa
     8461 agaacttaga gagaataatc taacctttga agaattagga ccaaattctt tgaataaaag
     8521 gaaggttata aacaacatag catatattat tgattttatg ttacattgtg atgatgtaga
     8581 aaagttaata gttgtactta ataaagtttt tatagatact gataatgaag aagaaataaa
     8641 gtatttttta gaagaattaa aaaactattc taccgaagaa attatttata attttgaatt
     8701 tagtaagtta gataatgatt taatagaatt taaagaagaa agtgatatat acttaagttt
     8761 taaaagagga atagatatta taaaacagat attagaatat ccaataataa ggttagacct
     8821 cttagttttg tttattggga aaaaacttag tttagaaaaa gaagataaag ctgtactgga
     8881 ttatatatct ttttatataa agtatctagt atcagaaaat ataaatatgg atttagaaga
     8941 tgtatataat ttattgtttg atgtaaagaa cagggtgttt aatcatataa tagatgtggt
     9001 atatgagata aatggatatg aaccagagcc tggtagtata acactatgta actatcataa
     9061 atcaaagggg atggaatggg attgtgtgtt tttactaggt cttgttgaat ataatttccc
     9121 tgacaatatt aatcaaaagt ttcagagtga taaatggtat ctaaaagaaa aatataaaaa
     9181 ccctatggca attattaaat cagaagttga agctatatta aaaggaagta tttcaacaga
     9241 ttatgctcat aaaacgaaga ttgattctat aaatgaaaag attagacttt tatatgtagg
     9301 gattactaga gcaaaggaaa tgttagtact ttcaggaagt gcttatagag atgaaagtga
     9361 tatagggaat aagagaaaag agcaaaaacc atgtatatat ttaagcagac ttaatcaaca
     9421 tattattgaa aaaaggtcaa attaatatat aataagttat taaaagattg tttgaaatat
     9481 atctaaaaga ggataaaaca atatgtacag taagtaacta ctaaaaaata aagttaagag
     9541 agaagtgata tgagtgaacg ataaattaaa atatttttct tatagtcaaa attcaattaa
     9601 cacatataaa tcatgtccat tgaaatttaa atataaatat attgatagaa taaattggaa
     9661 aaatgatgat gttggtagta gagagtatta tgaaacttta aaaacaggaa gagattttca
     9721 tttgatttgt gaaagatatt ttagcaatat acctcttgga atctatttta atgaggatga
     9781 taaaaatagt aaaaagtttt taaagtggat ggaaaatata aaaaaagttg ttcctattga
     9841 aaaaggaaaa acgtatttgc cagaatatga agtaaggatg acattaaatg gggatataat
     9901 acaggcaaag tatgatttag ttgtaattgg aaataacaat atagaaatat gggattggaa
     9961 aaccgagtct aaaaagattg actataaaca cgtagaaaat agaatacaaa ctattgttta
    10021 tatgttttta gcaaaagaag taatacctaa agttttaaaa atggacataa atgttaaaga
    10081 tataaatatg agatattatc aacctgaatt tgatgactta ccaattacca ttttatatga
    10141 tgaagaaaaa catgaagcaa atagaaataa aattcaaaat tatataagta tgataaaaaa
    10201 cactaattat gaagaacata catacgaaga caatctatac aatgatatag aaaaggtata
    10261 taataaagaa gaacgtatgt gctatagaaa taaaaagcat tgcaagtatt gtgaatttaa
    10321 taagttatgt aatggcaaag aaatagatta tagtattttg gaggcggaaa tttatgggac
    10381 ttaggtttgt attaggtaga agtggaagtg gaaaatccac ctatatacta gatgagatta
    10441 aaaaagaagc tcaaaaaaat gaaacgacat caattatact tttagttcca gaacagtaca
    10501 catttgaggc tgaaaataga gtaagtaaac tatttttagg aaaagaaaaa gataagtatc
    10561 taagagttag ggtacttagc tttaagacac taagtaatat agttttttca caagtaggag
    10621 gattgacaga tgtaaatata aattctagtg gaaaagcaat gatggtatat agagctattg
    10681 aagatgtaag tgaagaatta aatgtatttt caaaatcaaa atcgcagtct ggttttgtaa
    10741 gctcaattac agatatgata tcagaaatga aacaatacaa tataagccct gaaatgttag
    10801 aaaatatatc tggagaattg gataatgaaa ctttaagttt aaaattaaaa gatataagta
    10861 aaatatataa ttcttttgaa gggaaattgc atgaaaatta tgtagatgct caagatatgt
    10921 taacttcatt ggcaagtaaa attgaattaa gcagttattt agatggagct tgtgtttata
    10981 tagatgaatt tacaggtttt acaccaaatc agtacaatgt cataaagagt atattaaata
    11041 agtctaaaag tgttaatatc tctttgactg tagatgatat caactatatt gggtacagta
    11101 aatctgatat gttttccaga acgaaattta cttattcaaa attgactcaa ttgtgcaacg
    11161 aagaaggcat aaaaatattg ccacaagtaa atttaaacac aggtgttata aaaagatttg
    11221 aaaaagttaa ggaattacag cacttagaaa gattttataa tgcttatcca tataaaatat
    11281 attcaaatca aactgaaaat ataaagataa aagagtttaa caatttatat tcagaggtgg
    11341 aagagatagc cagagaaatt gtacatttag ttagagataa gaatgtcaga tatagagata
    11401 taaccattgc tacaagagat ttaaatagat atgatttttt agtacactct atatttaatg
    11461 aatataatat accaaacttt atagataaga agagagaggc aaaaagtaat ccaatagtta
    11521 ttttaattat ttcagcttta gaaatgaaga atagacgata tgggtatgaa actatgttta
    11581 ggtatttaaa aagtggactt ataggaattg ataatgatga tataaattta ctagaaaatt
    11641 atgtgttggc taatgggatt aaaggtaaaa aatggtttga tgaaaaatgg gattatagaa
    11701 taacccaaag tctttcaggt caagaaagtg aatttgaact ggaattaaaa gagaaaataa
    11761 atgaaataaa aaatagagta ttagagccta tagtaatttt acaagaaaaa ttaagaggaa
    11821 aaaatagagt aaaagaaatc tgtagatata tatatgaatt tttattagat ataaatatgc
    11881 cagaaactat agaaagttta ataataaatt ttaaggataa aggggaactt gatgttgcaa
    11941 atcaatactc acaagtttgg gacatagtag tggacatatt agaccaaatg gtggaactta
    12001 tgggtgatga aataatttct ttagaaaaat ttataaaatt aataacctta ggttttgatg
    12061 aatatgaatt aggactggtt cctcctagta tagaccaggt acttgtaagt agtgtggata
    12121 gaatgaaaaa tccagacacg aaatatttat acctagttgg aactactgat ggtgtgtttc
    12181 cgctgattac aaaggatagt ggaatattga gtgataatga tagggaaagt cttggaaaca
    12241 aaggaatcga agttgatatt gatagtaaga ctaggagttt tgaagaacag tttcttgtat
    12301 ataaagctct tacttcgaca tctaagaatt taaccataac atatccaata tcagaccatg
    12361 aaggtaaaac gcttagacca tcaataatta tatcaagact taagaagata tttccaaata
    12421 tagaaaataa aagttattta gtggaagaaa ataaaagcac tgataaagat atacttaaaa
    12481 aaataacggt taaatcccct acatttaatg aacttataaa cgtaataaaa aattatgaca
    12541 gtgatggtta caatacagaa gagattaata gtatttggtt agatatatat aggtactatt
    12601 taaaagatga aatctacagt tctataacaa aaaaagttat aaaaggtctt agttatacta
    12661 atcaagttca taagattgaa gagaaaaaaa taaggtcatt gtataaaagt aattctctta
    12721 gcatatctag gcttgaaaaa tatgctgaat gtccatttgc ttattttata caatatggtc
    12781 taaaagcaaa aaagcgtaaa gagtattcat ttacaccacc agatttagga acttttattc
    12841 ataatatttt agataggttt tcaaaagaac ttttacaaga taatttaact tggagagata
    12901 ttgatgaaaa atatatagaa ttaaagatag gtataatagt tgatgaaata attttaaaga
    12961 taccaggata tatattaaat agttctgaga ggtataaata ccttgcatat agattaaaga
    13021 atatgttgac aactgctata actataatta gtcagcaaat aaaacaaggt tcatttgaac
    13081 caatagatta tgaagttaaa tttggcaaca atggaaaata tccacctata aaaatggtgt
    13141 tagaaaatgg acaagaagta agtttaattg gacaaataga tagagttgat gaatttgaag
    13201 aaggagaaaa taaatatata agaataatag attataagtc aggcaataag tccataagtc
    13261 taacagaaat atattatggt ctacaattac aattacttgt gtatttagat gcaatccttg
    13321 aaagtgcaaa ggatgaagat ataaatataa atccagctgc aatactatat tgtagaataa
    13381 ataatccaat agcaaaattt aatgaagata aagatgatga agaaatacaa gaagcaatat
    13441 taaaagaact tagaatgaag gggcttgtag taaaagactc tcacatagtt aaagagatgg
    13501 ataaatcatt aatagatgga gaaaggaaaa actctttagt aataccagta ggtcttacta
    13561 aggatggaaa tgtaggtaaa agtacttcag caataagcta tgaggatttc aaactgctta
    13621 gaaaatatgt aaggcatgct ataaaggatt tatgtgaaga aatgttaagt ggagaaatac
    13681 gtatagctcc atataaacat aaagatggaa catcatgtga cttttgtgat tactctgcta
    13741 tatgtcagtt tgattcaact ataaaagata acaagtataa aaatttaaat aataagagta
    13801 atgaagagat aataaaaatg atgaaaggag atgttaatta gtgagttctc ctaaatggac
    13861 aaaagagcaa ttagaagtta tagaaagtag agaatgcaat ttattggttg ctgctgctgc
    13921 tggttcagga aaaacagccg ttctagttga gcgtataatt caaatgataa caagtagaga
    13981 aaatccaatt gatatagata agttattagt tgttacattt actaatgctg ctgcgtcaga
    14041 aatgagagag aggatagggg atgctatagg aaaagcctta gatgaaaacc cagaaaataa
    14101 acatttacaa aaccaacttg ttttattaaa taaatctagt attacaacaa tacactcatt
    14161 ctgtttggat gttataaaat caaactttca tagaataaac ttagacccta atttcagaat
    14221 aggagaccaa actgaatgtg ctattttgaa acaagaagca atagaggaag tatttgaaga
    14281 tttatatgaa gaaagagatg aggggttttt aaatttagtt gaaagttatg cagaaagagg
    14341 aggagataaa gaagtacaag atattatctt gggaatatat tcatttgcaa tggcttctcc
    14401 tgaacctaaa aaatggttga ttgactcagc agaacgattt aatattgatg aaaattttga
    14461 tttttcacag tctatttggg ctagagctat attagatact gtaaaaatag agattaatgg
    14521 tctttgtcta aatatggaaa gggcattaaa agaagtggaa tcaatagaag aattagaaac
    14581 ttttgcagaa aagttatccg ttgaatataa aaaaattgct gacatttcac aagcatgtaa
    14641 taaatcttgg gatgaggcat ataaaaagat ggcaagtatg tcctttgaaa attatgtaaa
    14701 aggagtaaaa agaatttcaa aagatgctcc ttcgtatata aaagaatcaa aagaaaaggc
    14761 aaaaactata agagataaga ctaagaagtc tttagaaagt atagtaagtg ctacattcaa
    14821 taaagataat gattctatta gagaagaaat aaaatatctt tataacatag ttaaaccaat
    14881 atctagtgtt gtactgagat ttgaagagga atatagcaat aagaaaagag aaaaaggaat
    14941 aatagatttt aacgatatag agcattttgc attaaatata cttacagatg tagatgaaaa
    15001 aggtaatatt gtaccttctg atatagcagt tggatataga aacaagtttt atgaaatatt
    15061 tatagatgaa tatcaggata gtaatctagt gcaggaagta ctgcttaaag ctgttgcaaa
    15121 tacagaaact ccaaatagat ttatggttgg tgatgtaaaa cagagtatat atagatttag
    15181 acaagcaaag ccagaattat ttttgcaaaa atataataac tataatgata aaaagggaag
    15241 ctcccataga aaaataatgc tttacaaaaa ctttagaagt agagaagaag ttgtagatgc
    15301 tgtaaattat atatttgaaa atataatgaa tgagaatata ggagaaattg aatatacaga
    15361 aaaagaaaga ctaaatttag gtgcaaattt taatgtggat acagacgaga aatctattat
    15421 tggtggagca acggagatac acctaataca aaaagataat aaacttgatg atgatattat
    15481 aaatgataaa gacgatagaa ttaataacaa agaaaatgaa atagaggaag aagaaaaatt
    15541 agataatata caacttgagg ctagaatggt tggaaacatt atcaaagatt taatgaaagt
    15601 caatgaagat ggaaaaattc aaaaggtcta tgataaggga atagatggat atagacctgt
    15661 ggaatttaga gatatagtta ttcttttaag agctacatct gcatgggctc cagtgtttgc
    15721 agatgaattg atgaatatgg atataccaac gtatgctgat gttggagtgg ggtattttga
    15781 tacgattgaa ataaaaacaa tattgtcatt acttcaaata atagataatc caatgcaaga
    15841 tatacctctt atatctgtat taaaatcacc tatatttgga tttacaccag aggatttgat
    15901 tgatattaga gttcagagta aagataaaat tttttatgag gttttaaaaa gtacagcaga
    15961 gtatgatgga tttacagatt ctcaaaatga aaatgagtct gagtttatac caagtgaaga
    16021 atgcataaac aaaagtaaag attttttaat taagctaaag gaatttaaag aaaagtcaat
    16081 gtacatgagt acagatgaat ttatatggta cttgtacaca aggactggat actatgccta
    16141 tgttggagca ttgccaggtg gaagtcaaag acaagctaat ttaaaagtat tgtttgagag
    16201 agcaaaacaa tttgaagaaa ccagtcttaa aggaatattc aactttgtaa attttataga
    16261 gaaattaaaa aaatctagtt ctgatatggg aagtgcaaaa acacttggtg agaatgcaaa
    16321 tgttgttaga ataatgagta ttcataaaag taaaggtcta gaatttccag tagtcatatg
    16381 ctctgcaatg ggtaaaaatt tcaatactca agattttaaa aagagtattt tatatcatca
    16441 taatttaggg tatggacctc aatttgtaga ctatgagaga aggatttctt ttccaagtat
    16501 agccaaagaa gcattaaaaa gcaaaataaa tatagaaaat ttatcagaag agatgagagt
    16561 tttatatgtt gcatttacaa gagctaaaga aaaattgatt ataactggtt ctactagaaa
    16621 tatacaagat agtataaaga gatggtcaaa tggaattgaa agtttagata caatatcaca
    16681 atacgagata ttaaaaggta aaaatttttt agattggata atgccttgtg tattaagaca
    16741 tagggattta tctaatctac tagaagaagt aggattagac gcagttttta atgttgaaca
    16801 taattcaaaa tggtatggaa agttgtggaa taagagtgat attttagtgg aaaagaagag
    16861 tgatgaagaa aaagaaagta ttgaagaaat tcttgaaaaa atagatgtag ataatcctga
    16921 tagtgattat tacagtgaaa tagaagaaaa attaaactat atatatccat atgaatttag
    16981 tacaagaaaa cctgctacta tatctgttac agaaataaaa aagatacaaa ataattatga
    17041 agaagagtta ataaatacta tatttgaaca aaaagtaata ttaaaaaagc ctctatttat
    17101 tcaaaatgaa gaagaaagag aaaaaataag tggaacagaa agaggtacaa tagtccattt
    17161 agttatggag gttttagact taaaaaatgt aagtagtgta aatgatataa aatcacaaat
    17221 aagaggtttt gtttcaaaag gtataataac agaaaaacaa gctagtatag taaatccata
    17281 taaaatatat aaattttttg cctctaacat aggaaaaaga atgttgaatg ctgaaattat
    17341 aaatagagaa aaatcaattt atgcacaagt aaatatgaaa gacatatata tttatgaaaa
    17401 gcttataaac aatgacgata aaaaacttta tgataatgaa agtgtcatgt taagaggtat
    17461 agttgatgct tattttgaag aagacaatca aatagttttg gtggattata aaacagattt
    17521 tgtaaatgag gaaaatataa atcaaataat agagaaatat aaaaaacagt tggatttata
    17581 tgcagatatt attgaaactt taactggtaa gtcagtaaaa gagaaatgta tatatttatt
    17641 tggagttgat gaagctgttt gttattagtt tttatatata aattaaacct aaaagataga
    17701 ggaaggggaa aaaatgagat ttattcatac atcagattgg catctaggga agtccctaga
    17761 aggccattct agaattgagg aacaagcaaa gttttgtgag gaatttataa aaatagtaga
    17821 atcaaatgaa atagatatgg ttataattgc tggagatgta tatgatactt ctaatccacc
    17881 agcacaagca gaaaaactat tttatcagac tgtatcaaga cttgccaata atggtcagag
    17941 gtgtgtatta ataatttcag gaaatcatga taatccagag agactctctg caataacacc
    18001 tctagcacat gaacagggga tacttatata tggttatcca ttaagtgcta cgatagaagc
    18061 taagtataaa gggtttgaaa taacatatgc aactcaggga tgtacaaaac tgaatataaa
    18121 tggagaaaat attgtggttg ctacattacc ttatccaagt gaaaaaagat taaatgaagt
    18181 tttttcaagt gaagatgagt ttgagaaaca aaaaaattat tctgaaaagg taggagatat
    18241 atttagaagt ttagaagaaa attttagaag tgatactata aatatagccg tatcacatat
    18301 atttgtaata ggtggagaga gtactgaatc agaaagacct atacaattag gtggaagttt
    18361 tttagttgaa agaaaagatt tgccagaaaa ggctcaatat actgcactag gtcatttaca
    18421 taaacaacaa aaagcttccg aacgtttaaa tgcatactat tctggttctc cacttcaata
    18481 tagcaaggat gaaagagcgt ataccaaagg ggcatacata gtggatataa aagctggtga
    18541 aaaaccaata attgaagatg tatattttaa taattacaaa cctatagaag tatttaaatg
    18601 taatggaata gaagaagcac tagatatatg tgagcaaaat caagatagag agatttggtc
    18661 atattttgaa ataaatactg atgagataat atcacagaat gaaattaaaa aaatgaagga
    18721 actattaaaa gacataatag aaataaaacc aataataaca tcttgttatg aacaagaaag
    18781 tgtagatata aaagaaaagt ctatggcaga gttgtttaga gagttctatt cttttagtaa
    18841 aggtgtagag ccaaaaggag aacttatgga tttatttcta gatataataa gtgaagaagg
    18901 tgaatcagca gatgagacca attagattag aacttacagg gcttaatagc tatattgata
    18961 aacaagttat agactttgaa aaattaattg aaagaggttt gtttgggata tttggaacta
    19021 ctggaagtgg aaaatctaca atcttagatg caataactat tgctatgtat ggaaatatat
    19081 ccagaaatac aaaagaatat ataaacagtg tgtgcgataa ggcaattata tcatacgagt
    19141 ttgagatagg aagcaaaaac actagaagaa gatacattgt agatagaacc attgctagaa
    19201 gcaaaacagg aacaaagacc tctaatgcta gattaataga agtattgaat gacaataccc
    19261 aaaatgtttt agctgataaa gttgtggaag taaatgaaaa agtagcgcag gtcgtaggat
    19321 taacggcaaa tgattttact aggtcagtag ttttaccaca agacaaattt aatgagtttc
    19381 taagattatc acgtgcagat agaagagaca tgttagagag aatttttaat cttgagaaat
    19441 atggaagaag tcttggcgaa aaagtgaaaa agagaaaaaa tatacagtta caaaatttaa
    19501 aagatttgaa atcaaaatta agtcaatatg atggaattac agaggaagta tataacaata
    19561 taaaccaaga attaatagag ttaaaaaatt tggaaaaaga taagaataat gctttagacc
    19621 tagctcaaaa atcttatgaa gaaagtaaaa cagtatatga agaacaatta aagttagaaa
    19681 aaaatgaact tagaaaaaat gagcttgatt taaaaaatag tgagataaaa gaaaagattg
    19741 ctcttgtaga aaatgatagt aacgctaaaa aggtagaccc atacataagt tcagttcaaa
    19801 atctagaaaa aaagatagat gaagatagct tcgcagtaag taatttagaa aagaaattag
    19861 caatattaaa tcaggagctt gaagttacaa aaaatagata tgaaaaaata aacaaaatta
    19921 agaatgaaga aatccctaaa ttgagtgaag aaaaaataag attgcaacaa gcaataaaat
    19981 tagaagaaga gttagtttta ttagatagag agttaaaaga gctaaaagaa agtggaatta
    20041 atttaaataa gactaaagtt gaattagaaa aagtaaagca ggtgtcagag tccagaaaag
    20101 atgcagttac taaatctata aaagaagttg aaggaaagat tgataaagta aatataagtg
    20161 cagaattaaa acaaaaaata tttctagcat atgaatacga gaaagattac aacaacgtat
    20221 tggaagaaaa aaatcaaaag ctaaataaac tagaagaaat actcaaagag acagaaaata
    20281 taaatttaaa agttagatat attgataaag ataagaatga tgtaaatcgt aatttagaaa
    20341 atttatcact tcacttggat gttcttctta aaaaatgtcc tggtaagagt gctgatttac
    20401 ttttaaaatc tgaatatgtt actgaattaa gaaataaagc aaataatact aaagaaaatg
    20461 aaattaagaa aagcagtata caagatgaat taaagataat acttgaaagt aagtttaata
    20521 ctgaaaggga agtaaattta ctaaatgaaa aacttgaaaa taatagaaag aacagagatg
    20581 acttagaaaa agaattagaa gaactaaagt atttaaattt agcctctgaa cttagacgtg
    20641 aattaaaaga aaatatgcct tgtccagttt gtgggtcaaa acatcatgaa aatcatgata
    20701 taactaagta tgatgaaaat atatcttttg tcaaagaaaa actggagaaa ttagaaaaag
    20761 aaaaaataag tataagaaac aatatagagg aattaaatgc taaagtaagt gggtatttat
    20821 ctatagaaaa aatgaagact aaagaacttg aagatgtaaa aggaaaacta ggggggattc
    20881 catctagtca attattaaaa aaacttgatg aagaacaaag aaaacttgca ttgttaaaat
    20941 ctaatattca ggagtgggag aaagaaaaag agagtactga aaataaagta acattagcta
    21001 aagaagaaaa aaataaaatt gaaaaagaag aattaaaaat aagagagagt ctgaataatt
    21061 ataagaaatt aacaagagat ttaaacatag aaatagaagg tttagaaaat aaatgtaaaa
    21121 aacttaaaca ggaataccta ggattaaaga cgattactaa agtctctaat ctattgtcaa
    21181 aagtaaaaga aataagggag aatgaaaaag aattagaatt actaagtact gggcattcaa
    21241 atttattaaa aaatagagac tcactagata ttaaaataag agaaaatgag agtaaactac
    21301 atgaaataga gatagaatta ataaaggcta gagaattata tgtagaaaag aaattgagta
    21361 gagataataa gtataaagaa gttattagca taacgaaagg tgatttagct aaaaatcttt
    21421 tacataatgt tgaagaaaat atatgtaaga tattagaaca agaagaatca agtaagaaaa
    21481 aattggaaga gcaaagatta gaatatgaaa aaaacattgc tgaaaagcac aatatagatg
    21541 gtagacttaa aactgctaag gaacaatata aagaccaaaa atcaacacta aataaactat
    21601 tggcagaaaa taaatttgaa agtatatatg cagtaaaaag agctttatta gatactgatg
    21661 cagtaaaaaa attgattgaa gaaatactag agcatgaaga agaacaaaag ttattatcat
    21721 ttaaaataaa atcatcaaaa gaaaaattaa atggaagaag cataaagaag gagtactttg
    21781 aacagttaaa agatgaaatt tataatttga aagtagaaat aggaaatata tccaaagata
    21841 ttggagctaa tcaaaatcag ttaataacat taaaagactc tttagataag ataaatgatt
    21901 ttaataaaca acttaaggta gttgaacaca atgtggactt attggaagaa ttagataaat
    21961 gtgtacaagg aaataaattt gtagaatatg tttctacaaa ccaattaaaa tatatagcgt
    22021 tggaagcatc aaaacgattg gatggaataa caaaaggaag atatgcactt gaaattgact
    22081 caacactaaa ctttgtaatg agagataact ttaatggagg agaaagaaga agcattgata
    22141 ctctatctgg tggagagaca ttcttgacat ctctatcatt agcacttgct ctttcatctc
    22201 aaatacaatt aaagggaagt gcaccattag aatttttctt tttagatgaa ggttttggtt
    22261 cattagatag tgaactttta gaaattgtta tagaatcctt ggaaagattg catagtaata
    22321 atctaagtgt gggtataata agtcatgtcg aggaacttaa aaatagagtt cctgttaagc
    22381 tattagtttc atctagtgag gctggaatag gttcaaaagt aaaaattgaa tatagttaga
    22441 aaatatatgt taattgaata tattatctaa tatttccaaa taatatgtaa ttgtgatata
    22501 ataaaaacta atattaaagt tatttataat taatattaat ataaaaacat gtaagtagga
    22561 gtgtggtaag tgttggaatc gcccaataat ttgattcaga ttattttttt aatagtatta
    22621 cttatagggt ctgcattttt ctcagcatct gaaacggcct taatgtcgtt gagtaaaatc
    22681 agaatcagat atatgcaaga tgaaggagtt aaaggagcta agttagtaag ttcattaata
    22741 gaaaatccaa ataagctttt aagttctata ttggttggaa ataacgtcgt aaatatagca
    22801 gcaacatcca tatcaacatc tttgtttata ggattaatgg gagaaaaagg agtggcactt
    22861 gctacagctg ttatgacagt attagtatta atatttggtg agattactcc aaaaacaata
    22921 gcagcaaata attcagaaaa ggtttctcta ttagtatcta aacctataaa agcaattata
    22981 tttatattaa gaccaatagt atggatattt aatataatta caaatattat atttaaatta
    23041 tttggtataa caaataaagg agctaaatca ttcataactg aagaagagct aaaaactatg
    23101 gtaaatgtaa gtcatgaaga aggcgtcctt gaaatggaag agagagaaat cataaataat
    23161 gtttttgaat ttggagatat gcaagctaaa aatgcaatgg tacaaagaat agatatggta
    23221 gctatagata tggaagatag ttatgatgag ataatacagg tatttaaaac tgaaaaatta
    23281 agtagaatgc ctgtgtatga agaaactata gatgatattg taggaatact taatataaaa
    23341 gatattatat ttttatctga tgaagaaata gagtcatttg atattaaaaa ttatatgaga
    23401 gaaccttttt tcacgtatga gttcaaaaag ataacacaac ttcttgaaga gatgaaactt
    23461 gaaaaaagtc agatggctat agttgtagat gagtatggtg gaacatctgg acttttaact
    23521 atagaagatt tagtagaagt cattgttgga gatatagagg atgaatatga tgaagaagag
    23581 gatgaaatac aagttataaa agaagatgag tatattgtag atggaagtac taaaattggt
    23641 gatgttaatg aacttattgg tgtaaacttg gaatctgagg agtttgattc cataggaggt
    23701 tttataattg gacacctaag cagattgcca gaagaaaatg aagtaattga agttgataat
    23761 ataagatttt gtatagaaag tatagaaaaa aatagaatta aaaaaataag aatatataca
    23821 taatgtaata atgttcttaa atttattaga agtgtataaa tataaaagat atcttttata
    23881 tttatacact tctttttatt ttgtattcaa ataaaactag tatgaaatgg acaaaataaa
    23941 aatataaatt agaagaaagg agatttttaa gatgagcata ctagaaaata attttttata
    24001 caaattaaaa aacaacacta tctttttttg tatatataca ttgttattta tttttattta
    24061 caaagcgttt ccatacatag ctccattttt tctaggtgct ataatagcac ttatgattaa
    24121 tcctatatca caaaagttag aaaataagtt tcatataaat aaaggtatct ctactcttgt
    24181 tctaagtttt cttgcagtgg ctatagtcag tacagttact acaataatag taataaattc
    24241 aatgaaagaa ttaatgggat ttttaaataa tatatctgct aatcctgagg atataagtaa
    24301 tactattatg tattttttaa ataaaataaa tgactttatg aaatcatttc aagaaatagc
    24361 caattttgat gtagaacaat tagtaaacaa attcagtggt gaagtaatgc aaattacaaa
    24421 aaatcttctt actagtatac ttggattggc tacttctatt ccatatatta taatatttat
    24481 aattaccttg tttattgcta cgtattttat agcaaaagac cttgataaga ttgaaaatag
    24541 tttttataat atgtttactg ttgatgttag aaagaaggta aaaaacgtaa agaaagaggc
    24601 agggctttca cttgttggat atataagggc ctatacaata cttatggcta taacattttt
    24661 tgcaatctgg ggaagttttg ctttatttgg attgaaatac ggtctaatag tagggtttgt
    24721 aggagcttta atggatttaa ttccattcct aggtataata acaatatatc ttccagtaat
    24781 tgtttattat tttcttataa aaaattattt tatagctata agtatgactg tgatattttt
    24841 tgttttgtct ttgattagag aaatacttga acctaaacta gtatcagtaa atgttggact
    24901 aaatccatta gctaccctag cagcgatttt tattggaatc caagtaaaag gaataattgg
    24961 agtaattttt tgtttgggtt tggtatgtat gcatgatata cttaagaagg tggatatttt
    25021 ttaattataa taattgatag attttttaaa aataaaattt tattcacagg taaataaaaa
    25081 aatattaatc ttattaagaa agagggtata tacgtgaaac aaaaagtagt ggaaagattt
    25141 ttaaaatatg tatcatttga tacaacatct aattctcagt gtgagaactg tccatcttca
    25201 gaaggtcaaa gagttttagc taagtatata gttgaagagc taaaaacaat gggtgttgat
    25261 gatgtgagtt tagatgaaaa tagttatata atggctactt taaaaggaaa tactgatggt
    25321 gtggatacta taggattcat atcacattta gatacaattg aagatgttag tggaaaagat
    25381 attaaaccaa aaataataga aaattatgac ggaaaagaca tagttttaaa tgaagcgtta
    25441 aatgttatta cgtatgtaaa ggattctcca gagttggaag aatttaaagg tgacgattta
    25501 atagtcactg atggaacaac tctacttggg tctgatgata aagctggtat agctgagata
    25561 gtgactgcaa tagagtatct aataaatcat ccagaaatta aacatggaga tataaaaata
    25621 ggatttacac cagatgaaga aattggtaga ggtgctgatt tatttgatgt tgaaaaattt
    25681 ggagcaaaat atgcatatac tttagatgga ggaatagttg gagaacttga atgtgaaaat
    25741 tttaatgctg caaatgcaac tattactata catggtagaa atgttcatcc aggttcagct
    25801 aaaaataaaa tggtaaatgc tatacatata gctgctgaaa tatcagaaat gttcccagca
    25861 gatgaaagac cagaaacaac agaaggatat gaaggatttt ggcatttaaa ttctataggt
    25921 ggaaatgtcg agaatgtaag tatggcttat attattagag accattgtaa agaaaaattt
    25981 gaaaatagaa aatctattat gatagagaat atagaaaaaa taaataagaa atacgataat
    26041 agagtggaat tggatttaaa agactcttat tacaatatga aagaaaagat tgagccagtt
    26101 atgtttatag ttgatatagc taaagaagct atggaggaat taggtataaa accacgttta
    26161 gttcctgtaa gaggtggtac tgatggagca agattatctt ttaatggatt accttgtcca
    26221 aatatattta ctggtggatt aaacttccat gggaaaaatg agtgtatacc agttagttct
    26281 atggagaaag ctactaaact aattgtaaga atagctgaaa aatatgctga aagagtttag
    26341 ttaaaaagta tttaaaaatt aagcatttaa agttataata gctatatcat tctttataag
    26401 tcaagctgat tataagcttg tgttgtactt aaaatggtat agctattttt gtaattattt
    26461 ttataaaaga taattatttt tagtttaggg tatcaataaa aagtatgaat atcaataggt
    26521 attaacattt aaaaggggga attgtattga aaattaaatc taaaaaaata atagcatttg
    26581 cactttcact tgggattatg ttgccaagtt gtgtatatgc agacaatatt agtaaaaatc
    26641 aaaatgcaca ggtagatatg aacaattatc ttcaaggtag aaaatctcca aaggaggaaa
    26701 aacttattgg tgaagataga tttgatacag cgataaaaat atctcaaagt ggttggaata
    26761 atggttcaga aagggtgttt ctagttaact caaattcatt gccagatgca ttggcttcaa
    26821 ctcctttggc aagtaaattg gatgcaccaa tactgcttac aaataaaaat agtataccat
    26881 ataatgtaac agaggaaata aaaaggctta atccagcaga agttatttta attggaagtg
    26941 aaggagctat ttcatcaagt gtaaaagaat ctcttgaaga tatggaagta ttagtcagta
    27001 gaatcggtgg agcagataga gaagaaacat ctttacttct tactagacag ctagatgata
    27061 ctggtgattt aggtgtctca aaagtggcag tggttaatgg gtataatgga ctggcagatg
    27121 caacttcaat atcaagccca gctgcaagtg ataatacagc tataatatat acaggtaagg
    27181 atagcataag aagtgaggca aagaatttta ttacacaaaa ctcaactaag acatacatag
    27241 taggtgggga gtacagtata agtaaaaaac ttgaaggaca gttagtaaac tcagaaagac
    27301 tagcagggac agatagaaaa gatactaatg cgaaagtttt agaaaagttt tatggaaaat
    27361 caagtaaggt taataatatg tattttgcaa aagatggaag tggtagagaa gctgatttag
    27421 ttgatgggct tgctgctgga gtattagcat caaaaacaaa gtcacctgta gtacttgcaa
    27481 gtggaagttt aagtagtgca cagaaaagtt ttataaaaaa agtaaaggct gataaatttg
    27541 tacaagttgg tggaggtaaa aatagtaaac catatgcaga agcattagcc ttacagtaat
    27601 attgtgtaaa tcaaaattaa tatataataa tagcaagtaa accaagttgc actttaatat
    27661 atataataaa ataagtaaac taagttatat ttcagtataa tatataataa aataagtaaa
    27721 ctaagttata tttcagtata atatataatg aaataagtaa actaagttat atttcagtat
    27781 aatatataat gaaataagta aactaaatta tactccaata taatatataa tagaaacaag
    27841 taaactaagt tatatttcaa tatagcatat aataaaacaa gtaaaccaga ttctatttaa
    27901 ttagaagttt aaggtattgt acttaaactt ctaattgaga tagaaataaa atggtttact
    27961 tgtctttatt atgaatttaa taaattaaag cttattttat ttttattaaa aatttactaa
    28021 tcattgatat ttattatatt tccagtattg atgtcaatta agtttatatc aagttcaagc
    28081 tcatcctcat catcagtttt tatgatatct ataattgcga cagaatggct tccatctttt
    28141 gggatagaag tacttcctgg atttattact attaaattat catccatgta tagttttttt
    28201 acatgagtat gtcctaaaac taatatgtca ccacccattt tctttgcttt gtcaataatt
    28261 tcttcttctg attctatata accatgattc aatataattc taatttcacc aaattggctc
    28321 atgacataag gactctgaat aggatgttct ataaccatct ggtcaacatc tgcatcacag
    28381 ttccctttta caatcacaat gttttctaat ttatttaatg tctcaataaa ttttttagga
    28441 ttatatcctt ctggaatatc atttctaggt ccatgatata agacatctcc accatgtaat
    28501 aaaacatcac aatcagataa tacatttaac gctttttcaa agtaaagtaa gctaccatga
    28561 gtatcactca ttattcctat tttcatatta aaaatcctcc taagtacagt ctataaaaat
    28621 ttttcagata ctctatgcca aaactcatag tttgacattc taagtaattt tatttttgca
    28681 tcagatatac taacttttat attttcgatt tgtctaaatc tgtgctcaac tccatcaacg
    28741 acaatcaata cagaatcttc aaatctatat tctggtgcaa tctttataac agattcattt
    28801 gaacatatta tacttgatgt aaagcaccta tatgcattgg tatttatcgg atgtaaaggt
    28861 gtaatctgca taagttcaag atttatatca acaatactac ctccagcaga atagttatag
    28921 gctgttgaac ctgtggaagt agaaataatc ataccatctc cactaaaatt ttgtatatgt
    28981 ttattatcaa ggcttaaatt taggtgtata gtcctagact tgtctcctct tataacaacc
    29041 tcatttacag caagcatatt agaaccacta gtagttgtat atacttccgc attaagaagt
    29101 gacatttctt gaataatata atcttttttt gtataagctt caataaagct atcaatctta
    29161 tctggtaaaa tatcaggaaa aaaccccaga tgacctgtat ttattcccat tatgggaatc
    29221 tcaggaaaat cgaaatctct aactgttctt aaaaaagagc catcaccacc aattgatata
    29281 ataagctctg tgtctggata aatatctgaa tacacttcaa agccagcatt gataagtttt
    29341 ctagttaaga gttctttagt ctcaagggac ttatttaatt ggtttgtatt tatagttata
    29401 attcttttca tatattcacc tcttcatact ttgtattata acatagtttt ataattctta
    29461 atttataaat ttataaatga cctttgtagt gaatgtgtta aaatatgtat aggtgggtat
    29521 aaaaaaatgc ataagaggtg aagatgtgtt tagcataagg aatatcacaa aaaaattagg
    29581 aaaattcaag ttaaataata taaacttaga gttaaaggaa ggggatattg ttgggattat
    29641 aggaccaaat ggttcgggaa aaacgacttt aataaaaatt ataatgggga ttattgatgc
    29701 agatgaaggt gaaattgaac tttgtaatga aactattgaa aattctccaa taagctttaa
    29761 aaacaatatt ggttttgtat atgattcttt acaattttat ccgcatttaa aggttaagga
    29821 atttagaaaa atagtttctt tattttataa gaattttgat agagaaaggt ttgatgaata
    29881 ccttaataag tttgatatag aagaaaatat gcatattgaa aatttatcta aaggtcaatc
    29941 tgaaaagctt atgttatcaa gtgcacttag tcacaatgct aagttattga ttttggatga
    30001 accaactgct gggatagacc caattgtaag aactgaaata atgcagtact tacaagattt
    30061 tgtgaaaaat ggaagtagta gtgtaataat ttctactcat aatactgata atttaattaa
    30121 aattgctgat tatcttgttt ttataaatag aggaaatcag atttttactg ttaagaaaga
    30181 attaatagaa caagaatata agataattag ggcaaataaa gcagagttag aagcaattaa
    30241 agaaagcata gttggtgtga aagagtataa atattataat gaggcacttg ttaaagttgg
    30301 agatagcttg aaagtaaaaa gcctattgat agaaattgat aagcataagg tcaaaaatcc
    30361 tactatagaa gaactaatgt attattatgt aaatgaggtg agatgatgtt caatttaata
    30421 agaaaagatt taataatagg gattagttca gatggtatcc gtaatttaaa gtacatattg
    30481 ctattttttg tgttttattt tttccttaat tcaatttcat attatacagt aagtattgtt
    30541 gttagttatt tgatatttat aaatacgttt gagtgtgatt atgaaaatga ttcaaggatt
    30601 tttataagga gtatgccagt tagtatagaa gatatagttt actcaaaata tttattaggt
    30661 gtaggattaa taatttctgt aacaataatt gtgtccttac taagtaaatt gacatcacta
    30721 gtgttcttta gaaatatggt tttaaatgat gtattttttt ctgtaaatat atttttagca
    30781 attttgacga ttttactgcc tttaattttt aagtttggat atggaaaaat gaaagtttgt
    30841 ggttttatag taagtatttt aatttacttt gtatatggaa gtcttttgaa gatgattagt
    30901 atgattgtat atcaagtaaa gcattttaat tatagtaaag ttggaggagt atatctttca
    30961 aattatgtaa ctgatatagc taatactaag tatataaatt tatatagtat gacattttta
    31021 acaataataa tttttataat atcaatgtat ttttctatta agatttcaaa aaagaataag
    31081 tttaattatt aaaattttga ttaatattat agcacaatag cacaaaatat aaggagacta
    31141 aaaatgaaga agtttataaa agtttcattt tttattttgg ggatttttac actattcata
    31201 gctataaata aattagtata tagagatatg gtaagtgtca aagattatga aataaatcat
    31261 ttagaggaaa ttgtttttga ttttgatagc aggagaagta gagatgttgg tactattgta
    31321 agatttaaaa taagcaataa tagtaaatat agttataaat taaacagtgc taaaatgaag
    31381 tttgaaaatt gtgtggaaaa taaaaaggga atgaataagt gttctgcata tgtaaatgta
    31441 gatttattta atgaaaaaaa ttctataact gaaagaactc tgaaatatgg aataaaacca
    31501 aataatcaag gttatgttga ttttgtaatt ccaaaaggac taaattttga ttataggtac
    31561 tttaatgaat ctggtatgag tgtagagtat aaaggagaat atattgtcaa tattccaatg
    31621 gcaaaaggac tttatctagt agttggaaaa aataatgata catggaatgc taatatcatg
    31681 gaataatttg aaaaataaat caattataga tataattaag aataatatga aatttataaa
    31741 agttcagact aggagggata tttaatgtca ataagtaatg taagagagta ttttaaacaa
    31801 tttggcaagg aagacagtat attagaattt gaacaatcta gtgctactgt ggaacttgca
    31861 gctgaagcag ctggggttat tccagcaaga atagctaaga cactctcatt taaaatagga
    31921 gatgatgcaa ttttaattgt gacagctggt gatgctaaga ttgataataa gaagtataag
    31981 gctgaattta attgtaaggc taaaatgttg acaccagaag aagtcttgga gtttactgga
    32041 catgctattg gtggagtctg tccatttggt ttaaaaaatt ctataaaagt ctatttagat
    32101 gattcaatga aaagatttga tacagtattt cctgcatgtg gcagtagtaa ctctgcaata
    32161 gaacttacat gtgaagaaat ggagaagttt tctaagtgtg aaaaatgggt agatgtttgt
    32221 aagaattggt aaaaaaatat agtaaactat agtaggaatt agtaaaaaac tacctctgta
    32281 tacaatctat acagaggtag tttttttgtg taaatattta taaatctaag aggaaaatct
    32341 aatttaaact aataatccaa aataaagtta aaaaattctg attttttttc gaaacaataa
    32401 aaaaatgaca aaaaagtgga aaaaatgtaa taaatattgt taaaaaaata attagaaatt
    32461 attgaaaaat tatcctttga gtgatactat tatagatgta agatatttaa aaataaaaaa
    32521 tagtcagata aaaatacgat tatttagctc tattaaaata atttttatac gataaaaatc
    32581 ttctgtacat ggctaaaaaa cagatgtaca gacaatattt aatgtttaat ataccctaat
    32641 ataaatatcg taaacaaatt attttatctg taaccagtgt gaaagaaatc ttattctaac
    32701 ttgaaatttc acaaaattcc aaaaagcgag atttttttta agtatagttg attttaaatt
    32761 aacaatttat gattaaatta atgtcataat tggttagtat aatcacatat aaatatagag
    32821 cgtagtttga ttaaggttat aaatttctcg acgtatattc aaatacctta ttatagatgt
    32881 tgccgagatt ttaattaata aatgaaaata aaatatttat aaaatactga ggaggctatt
    32941 atggatttaa attctaaaaa atatcagatg cttaaagagc tatatgtaag cttcgctgaa
    33001 aatgaagtta aacctttagc aacagaactt gatgaagaag aaagatttcc ttatgaaaca
    33061 gtggaaaaaa tggcaaaagc aggaatgatg ggtataccat atccaaaaga atatggtgga
    33121 gaaggtggag acactgtagg atatataatg gcagttgaag aattgtctag agtttgtggt
    33181 actacaggag ttatattatc agctcataca tctcttggct catggcctat atatcaatat
    33241 ggtaatgaag aacaaaaaca aaaattctta agaccactag caagtggaga aaaattagga
    33301 gcatttggtc ttactgagcc taatgctggt acagatgcgt ctggccaaca aacaactgct
    33361 gttttagacg gggatgaata catacttaat ggctcaaaaa tatttataac aaacgcaata
    33421 gctggtgaca tatatgtagt aatggcaatg actgataaat ctaaggggaa caaaggaata
    33481 tcagcattta tagttgaaaa aggaactcct gggtttagct ttggagttaa agaaaagaaa
    33541 atgggtataa gaggttcagc tacgagtgaa ttaatatttg aggattgcag aatacctaaa
    33601 gaaaatttac ttggaaaaga aggtcaagga tttaagatag caatgtctac tcttgatggt
    33661 ggtagaattg gtatagctgc acaagcttta ggtttagcac aaggtgctct tgatgaaact
    33721 gttaaatatg taaaagaaag agtacaattt ggtagaccat tatcaaaatt ccaaaataca
    33781 caattccaat tagctgatat ggaagttaag gtacaagcgg ctagacacct tgtatatcaa
    33841 gcagctataa ataaagactt aggaaaacct tatggagtag aagcagcaat ggcaaaatta
    33901 tttgcagctg aaacagctat ggaagttact acaaaagctg tacaacttca tggaggatat
    33961 ggatacactc gtgactatcc agtagaaaga atgatgagag atgctaagat aactgaaata
    34021 tatgaaggaa ctagtgaagt tcaaagaatg gttatttcag gaaaattatt aaaatagata
    34081 aatattaaaa tatacacaat aggtcgatat taaaatagat atggaggaag gatttatgaa
    34141 tatagtcgtt tgtataaaac aagttccaga tacaacagaa gttaaactag atcctaatac
    34201 aggtacttta attagagatg gagtaccaag tataataaac cctgatgata aagcaggttt
    34261 agaagaagct ataaaattaa aagaagaaat gggtgctcat gtaactgtta taacaatggg
    34321 acctcctcaa gcagatatgg ctttaaaaga agctttagca atgggtgcag atagaggtat
    34381 attattaaca gatagagcat ttgcaggtgc tgatacttgg gcaacttcat cagcattagc
    34441 aggagcatta aaaaatatag attttgatat tataatagct ggaagacagg cgatagatgg
    34501 agatactgca caagttggac ctcaaatagc tgaacattta aatcttccat caataacata
    34561 tgctgaagaa ataaaaactg aaggtgaata tgtattagta aaaagacaat ttgaagattg
    34621 ttgccatgac ttaaaagtta aaatgccatg ccttataaca actcttaaag atatgaacac
    34681 accaagatac atgaaagttg gaagaatata tgatgctttc gaaaatgatg tagtagaaac
    34741 atggactgta aaagatatag aagttgaccc ttctaattta ggtcttaaag gttctccaac
    34801 tagtgtattt aaatcattta caaaatcagt taaaccagct ggtacaatat acaatgaaga
    34861 tgcgaaaaca tcagctggaa ttatcataga taaattaaaa gagaagtata tcatataatt
    34921 taagggggga taaagaatgg gtaacgtttt agtagtaata gaacaaagag aaaatgtaat
    34981 tcaaactgtt tctttagaat tactaggaaa ggctacagaa atagcaaaag attatgatac
    35041 aaaagtttct gcattacttt taggtagtaa ggtagaaggt ttaatagata cattagcaca
    35101 ctatggtgca gatgaggtaa tagtagtaga tgatgaagct ttagcagtgt atacaactga
    35161 accatataca aaagcagctt atgaagcaat aaaagcagct gaccctatag ttgtattatt
    35221 tggtgcaact tcaataggta gagatttagc gcctagagtt tctgctagaa tacatacagg
    35281 tcttactgct gactgtacag gtcttgcagt agctgaagat acaaaattat tattaatgac
    35341 aagacctgcc tttggtggaa atataatggc aacaatagtt tgtaaagatt tcagacctca
    35401 aatgtctaca gttagaccag gggttatgaa gaaaaatgaa cctgatgaaa ctaaagaagc
    35461 tgtaattaac cgtttcaagg tagaatttaa tgatgctgat aaattagttc aagttgtaca
    35521 agtaataaaa gaagctaaaa aacaagttaa aatagaagat gctaagatat tagtttctgc
    35581 tggacgtgga atgggtggaa aagaaaactt agacatactt tatgaattag ctgaaattat
    35641 aggtggagaa gtttctggct ctcgtgccac tatagatgca ggttggttag ataaagcaag
    35701 acaagttggt caaactggta aaactgtaag accagacctt tatatagcat gtggtatatc
    35761 tggagcaata caacatatag ctggtatgga agatgctgag tttatagttg ctataaataa
    35821 aaatccagaa gctccaatat ttaaatatgc tgatgttggt atagttggag atgttcataa
    35881 agtgcttcca gaacttatca gtcagttaag tgttgcaaaa gaaaaaggtg aagttttagc
    35941 taactaattt cttggggagg gtattatgag tacaagtgat gttaaagttt atgagaatgt
    36001 agctgttgaa gtagatggaa atatatgtac agtgaaaatg aatagaccta aagcccttaa
    36061 tgcaataaat tcaaagactt tagaagaact ttatgaagta tttgtagata ttaataatga
    36121 tgaaactatt gatgttgtaa tattgacagg ggaaggaaag gcatttgtag ctggagcaga
    36181 tattgcatac atgaaagatt tagatgctgt agctgctaaa gattttagta tcttaggagc
    36241 aaaagctttt ggagaaatag aaaatagtaa aaaagtagtg atagctgctg taaacggatt
    36301 tgctttaggt ggaggatgtg aacttgcaat ggcatgtgat ataagaattg catctgctaa
    36361 agctaaattt ggtcagccag aagtaactct tggaataact ccaggatatg gaggaactca
    36421 aaggcttaca agattggttg gaatggcaaa agcaaaagaa ttaatcttta caggtcaagt
    36481 tataaaagct gatgaagctg aaaaaatagg gctagtaaat agagtcgttg agccagacat
    36541 tttaatagaa gaagttgaga aattagctaa gataatagct aaaaatgctc agcttgcagt
    36601 tagatactct aaagaagcaa tacaacttgg tgctcaaact gatataaata ctggaataga
    36661 tatagaatct aatttatttg gtctttgttt ttcaactaaa gaccaaaaag aaggaatgtc
    36721 agctttcgtt gaaaagagag aagctaactt tataaaaggg taaaaatcta attaaaaata
    36781 tatttgctgt taactagatt aaatagtatt ttaatctagt taacagaata taaatactaa
    36841 aataacagga ggttataact atgaaattag ctgtaatagg tagtggaact atgggaagtg
    36901 gtattgtaca aacttttgca agttgtggac atgatgtatg tttaaagagt agaactcaag
    36961 gtgctataga taaatgttta gctttattag ataaaaattt aactaagtta gttactaagg
    37021 gaaaaatgga tgaagctaca aaagcagaaa tattaagtca tgttagttca actactaact
    37081 atgaagattt aaaagatatg gatttaataa tagaagcatc tgtagaagac atgaatataa
    37141 agaaagatgt tttcaagtta ctagatgaat tatgtaaaga agatactatc ttggcaacaa
    37201 atacttcatc attatctata acagaaatag cttcttctac taagagacca gataaagtta
    37261 taggaatgca tttctttaat ccagttccta tgatgaaatt agttgaagtt ataagtggtc
    37321 agttaacatc aaaagttact tttgatacag tatttgaatt atctaagagt atcaataaag
    37381 taccagtaga tgtatctgaa tctcctggat ttgtagtaaa tagaatactt atacctatga
    37441 taaatgaagc tgttggtata tatgcagatg gtgttgcaag taaagaagaa atagatgaag
    37501 ctatgaaatt aggagcaaac catccaatgg gaccactagc attaggtgat ttaattggat
    37561 tagatgttgt tttagctata atgaacgttt tatatactga gtttggagat actaaatata
    37621 gacctcatcc acttttagct aaaatggtta gagctaatca attaggaaga aaaactaaga
    37681 taggattcta tgattataat aaataagaat ttgggaatta aaagtttaaa taaaattgtt
    37741 taaaaaacaa tttcggatat atgaaaaatc taatttaatg ggggtaatga atatgagaga
    37801 agtagtaatt gccagtgcag ctagaacagc agtaggaagt tttggaggag catttaaatc
    37861 agtttcagcg gtagagttag gggtaacagc agctaaagaa gctataaaaa gagctaacat
    37921 aactccagat atgatagatg aatctctttt agggggagta cttacagcag gtcttggaca
    37981 aaatatagca agacaaatag cattaggagc aggaatacca gtagaaaaac cagctatgac
    38041 tataaatata gtttgtggtt ctggattaag atctgtttca atggcatctc aacttatagc
    38101 attaggtgat gctgatataa tgttagttgg tggagctgaa aacatgagta tgtctcctta
    38161 tttagtacca agtgcgagat atggtgcaag aatgggtgat gctgcttttg ttgattcaat
    38221 gataaaagat ggattatcag acatatttaa taactatcac atgggtatta ctgctgaaaa
    38281 catagcagag caatggaata taactagaga agaacaagat gaattagctc ttgcaagtca
    38341 aaataaagct gaaaaagctc aagctgaagg aaaatttgat gaagaaatag ttcctgttgt
    38401 tataaaagga agaaaaggtg acactgtagt agataaagat gaatatatta agcctggcac
    38461 tacaatggag aaacttgcta agttaagacc tgcatttaaa aaagatggaa cagttactgc
    38521 tggtaatgca tcaggaataa atgatggtgc tgctatgcta gtagtaatgg ctaaagaaaa
    38581 agctgaagaa ctaggaatag agcctcttgc aactatagtt tcttatggaa cagctggtgt
    38641 tgaccctaaa ataatgggat atggaccagt tccagcaact aaaaaagctt tagaagctgc
    38701 taatatgact attgaagata tagatttagt tgaagctaat gaggcatttg ctgcccaatc
    38761 tgtagctgta ataagagact taaatataga tatgaacaaa gttaatgtta atggtggagc
    38821 aatagctata ggacatccaa taggatgctc aggagcaaga atacttacta cacttttata
    38881 tgaaatgaag agaagagatg ctaaaactgg tcttgctaca ctttgtatag gtggaggaat
    38941 gggaactact ttaatagtta agagatagtt ttagattata atatttacaa attaaatatt
    39001 taattatgaa tttaacctgt aagaataact atttgttatt cttacaggtt tttatagtta
    39061 aaaataatta ttatctatta aacaaaaata gtgtaaaata tataatatca tgattttgaa
    39121 gatataaaaa agtaggaaga tataaaagaa agtaggtaaa agtttgttta aaaaagagaa
    39181 tcaaagatat aatcttatat cgtatacaaa tgaagaagaa atgactttaa aagaagtttt
    39241 attggacaag ctaaatttct cagttaggtc attatcaaaa atgaagaggg aaaagagtgt
    39301 tttagtaaat ggagtatata aaaaaccgag tttaaaggtg tatagtggtg atttaataga
    39361 agtaaaaata gacgaggaaa aagcaaattt tgaacctcaa gatttaaatt tacagataat
    39421 ttatgatgat tttgatataa ttatggtgaa taaacctccg tttatggtag ttcacccaac
    39481 aaaaagccac tatgataaaa caatagcaaa tggtattagt tactatatag ataatcaaaa
    39541 agaaaatgta aaaataagat ttgtaaatag gttagatatg aatacttcag ggttagttat
    39601 agtagcaaaa aatgcttatg cacatcatac tttgtctaca gcaatgagtg aaaataaagt
    39661 tgaaaaaaag tatataacag tagttgatgg aattataaaa gaaaatgagg gaactataga
    39721 tgagccaatt tatagaccta cagaagattc aataaagagg ataatagatg aaagaggaca
    39781 gtcatctgtt actcactata aagtaataga aagactagaa aatgcaactg tattagaagt
    39841 aagcttagaa actggtagaa cacatcaaat aagagtacat atggctcata taggtcatgg
    39901 aataataggt gatgagttgt atggttatgt agatgaagat ctaataaata ggcaagcact
    39961 tcatgcatat aagctagagt ttgaacaacc aagaacaaaa gaaaaattga aatttaaagc
    40021 agatatacca gaggatatga aagagttaat atcgaaatta agataatggg gtgatatata
    40081 tgataataca taaatttata atacatgttt tggacaaaaa tagtgatgtt ccaatattaa
    40141 atgactttga aggcaaagtt aatcaagaag tagatggttt tttccagaaa gctataaaaa
    40201 gaattgcaaa agatgaggat ttaagaaaag gtgtttttaa agattataat gacaatttaa
    40261 ttaaaaactg ttgtgaacaa ataatatatg atgaaagtac ttttttgaaa aattctaaag
    40321 aaattgcatc ttacttgttt gatgttatga aaattaatgc tgcactagaa tcttgtgatt
    40381 tggcaatttg cttatacact attaaagatg aaaagagtgt agcaatactg aaattagatt
    40441 ataaaaagtt gtacactcat tcaattgaat ttgtggatga taaatttaat attcaaatgg
    40501 tttcaaatga aattggtatc ccagagactt taagacaaaa gcaaggagct ttgattagtc
    40561 taagtggtat aaatgatgag tttcatctaa ggcttttaga taaggatgct gaaaaagaag
    40621 ggtcagaatc taagtttgta acagaatttt taaatgctaa aaaaatagat gatgataagt
    40681 acaagaccaa ggtatttaaa aatacagctg aaaattggat aaccaatgct cttagtaatg
    40741 atataaagca agctgaagat gtaagaagta tattaaatta tacactgaag gaaaaacatg
    40801 aagttgatat aaatgacttt gttgataatt caattaaaga tgatgagtta aaggatagct
    40861 ttaaagagca tatggaagaa aaaggtcttg acgaaagttt tagtatagat aaaaaatggg
    40921 ttgagaaaaa gcttaaaaaa agaagtataa aaacggataa tggttttgac ataaaaggga
    40981 atctaactga ttttgaagac ccaatgaagt atactgtaaa acaaaatcaa gatggaacta
    41041 tagatataat aataaagaat gttacgtttt atgaagaaaa gtaatttata tacttagtat
    41101 ataaattaaa tataagagcg tgtattttat atattgtaaa taaatgtaat ctagtctgtg
    41161 cgaactctaa tataatttat tatgtagaag tttacacaga ctatttatat ttgtagacaa
    41221 aacgatacta tttgttttct tcgatatatt tacatatatc accaatacat ttaaagtttt
    41281 cagcttcctc gtctggtatt tctattccaa attcatcttc aagggccatt ataatttcaa
    41341 cagcatctaa tgaatcagct tctaagtcgt ccattaaaga tgcttccata gttatctcat
    41401 ctaaattgtc tacccctaat tgttctgcta ttatttcttt tattttctca aacattttaa
    41461 gcctcctaaa gcagttttaa ttaattttaa tgttagttta atataatatc aagaattttt
    41521 caatatggaa tctataaaaa ataataaaat tttataaatg tagtaataaa gtattatttg
    41581 atgaataaac tttattgata acaaatataa cttaggagga aatgctatga aatatgtagg
    41641 actattacta acttcagtag gaatgttttt acttatagca gtaaattttt attataattc
    41701 aataacttta gatatgcaac gtatagagga ttatgtaatg gagaccaatt taatccttga
    41761 agatgtagct gaaaaggaga gttatgtatc taatgaaaaa gaagattaca tatcaaggtt
    41821 aatgcatgta aagaaaggaa tagaaaattc aaaaacatcc ttcttgatag aaagatataa
    41881 ggagtacaaa ataaaatcaa tagaaagttt aatctatact atatcagagg agaaaaaaga
    41941 ttatctggat gaagttgata gatacaataa acttggtgaa aaagaaataa ataaactaat
    42001 caataaaaac tttttagaag taacttatct gtctattact acatatattt aattaaagag
    42061 acaaaactta gtctcttaat gattcaagga ggattagtta tgacaaaatt agaagacaat
    42121 atggaacgtt tctttggagg atgcgaagga ttttttggga ataaaatgtt gataataata
    42181 gttatagtat tcttactatt atgcacagac attttagaag acttattatg cgatgacaat
    42241 atatggatat gggttatatt aatagtattg ttattattta acttcgatga tggttgttgt
    42301 tgctaaaaaa tattgattat taaataggta aaaccagtaa cttatacaag ttatggtttt
    42361 acctttttta gttcaaatta aaaaatttaa aaaaatagta aaaatacatt agcaaaatgg
    42421 aaaccaaatg catagtatat gttaggagcg aaaagctcaa caaaatatca acaggaggta
    42481 acgtataatg ttagatagat tctttggaga agaaggatgt tttggtggag gaggatggtg
    42541 gataatagta ctattcttcc tattcttagc ttttggagat agctgggcag aatttgacat
    42601 aatggcatgg ataccattcc taatagtttt attaatactt tgctgctgtg gtggatgctt
    42661 agaataagaa cacagttatt aaaaaaagga gggctttgtt atgttagata gattttttgg
    42721 agaagaagga tgctttggtg gaggaggatg gtggataata gtactattct tcctattctt
    42781 agcttttgaa gattgctgga gagacattga cataatgtca tggatacctt tcttaatatt
    42841 attgctaata acttgttcat gtggtggatt ctttgatggt gaagtaggtt gcggctgcta
    42901 atacttaaat cattagaata aaaaaatgct ggtattttat accagcattt ttttatttta
    42961 ttttttaata tgatttaaat taagaatgaa tattattaaa tttgttgaat atagggtata
    43021 atataaaata taatgtattt aaatgtactt gcttttatgg taaaataaaa acttatataa
    43081 atgtagttaa aataggaacc ttcaaaaatt tggttcagtt ttagataaat ttagtaaaat
    43141 aaggaggatg aagatgaaag gcaatataac gataaaagat gttgctaaac aagcaggagt
    43201 gtcaatatct actgtatcta gagttataaa tgattcaaaa cctgtaactg atgaagtcaa
    43261 acaaaaagtt ttagaggtta taaaagagac tggatatata ccaaatccac ttgctagaag
    43321 cttagtaaca aagaagagtc aattaatagg ggtaatagtt ccagaagttt cagattcttt
    43381 tgttaatgag gtgttaaatg ggatagaaga ggttgctaaa atgtatgact atgatattct
    43441 tttagcgaat acatactctg ataaggaaca agaacttaag agtataaatc tattgagagc
    43501 aaaacaagtg gaaggtatag ttatgatttc atggatagtt gaacaagaac atatcaacta
    43561 tatacaaaat tgtggaatac cagcgacata tataagtaaa actgctagaa attatgatat
    43621 atatacagta agtactagca acgaagaagc tacttttgat atgacagagc atcttataaa
    43681 gaaaggtcat gaaaagatag cttttataat gactagtaaa gatgatactg ttttagaaat
    43741 ggaaagactt gctggttatg agaaagcact ttcaaataac aatatagaat tagacaagag
    43801 tttgattaag tatggtggaa ctgattatga gagtggatac aatagtatga aagaactatt
    43861 agatgatgga ataatacctc atgcggcttt tgtaacaggt gatgaggctg ccataggtgc
    43921 tataaatgct atatgtgatg ctggatataa ggttccagaa gacatatcag ttgcaggatt
    43981 taatgatgtt aagatagcta gaatgtatag acctaaactt actacagtat atcaacctct
    44041 atacgatatg ggagcagtag caataagaat ggttataaaa ttaataaata aggaattaat
    44101 tgaaaataag aaaatagagt taccttatag aattgttgat agagaaagtg ttacagaaag
    44161 aaaaaaataa aactattaaa atcaatcagg tagtgcctta ggcactacct gattttttat
    44221 gtcaataata tcaaatttaa taatagatta actaaaaata attatctaat tgcttaaata
    44281 gtttattttt atctattcat gaggattaga ctttttagtt ttcttaaata aacttttaga
    44341 ttttttttgt tgactacctg gtgtattttt tggtgcaggt gaatttgact tacctttagt
    44401 aggtttagcc ttcttagttt tagctggttt agtatctctt tggttttctg catctgagat
    44461 tttttccatt atattatcca gttttttgcg ttgattttca tctaaaaatg ctttgaattt
    44521 tgatactact tcatctctgc catctagatt cttacctatt tttataagtt cctccataag
    44581 ttcattttct gattttcctt tgtaactatc agccatcttt tctattttat ccttgtcaat
    44641 atttttttgt ttagccattt tttctaatga ctctgtatct aattttttca taaaaaaacc
    44701 cctttctata aatatatatt gaattatatt catactattt atatatagaa ataatattga
    44761 agtggtgaat tgtgagtgat atataatata aataaaaatt cttatagata atatatatgc
    44821 actgagcttt aaaaatggaa cattaaaata tgaaaaacat actttaatat agggcaatta
    44881 tataatataa gggggaattg tcttgaataa cttactattt ttgattggag tgattgcatt
    44941 gagtaatggt aatatctcta tatttgatga taaaaataaa tcaaaaggaa ataatagagt
    45001 tagaaaaaac aaaaaaaatg caaatgataa actttcacag tctacacatg gcaatttaag
    45061 gtttgatgca aatgatataa aaagaggttt aaggctcatg gatttaagtg aagaagattt
    45121 agaaatggga atggaaataa taacaagaac taaaaaatac atgtcaagag atgaaagaaa
    45181 aatactaata aaaatagaaa gtgttttaga tttagttaga ggaataaaaa aattaaataa
    45241 tatagatatg gtagatacag aagatgaaac ggattttttc agaaaaatgg atagtgatga
    45301 taaaaagaat atgatgataa aggaaattat agatgtattc ccagaaaaaa gaaaaaattc
    45361 agttgaaaaa gctataggaa tgaaaaagaa gatagattta tttgcagaat tatttttacc
    45421 agatgacttt ggtgaaggtg gatttagttt gagctctttg gcaaatataa acaatcttgg
    45481 tagtatgaat aatctcaaat tgttaggaag tcttttaaga ggtgatgata gtaataatga
    45541 tgatgaagac aataatgatg agttaaatta tgaagacgaa gaattagatt gtgaagacaa
    45601 agaattggat gatgatgagt taacagatga aggtgaaatg gaggataatg aagatgaatt
    45661 agtagaagat aagaacacag gctatgaaaa tatagaaaat gatgaagata tagtatacga
    45721 tgaggaacta tacaacatta atgagcaaga atccgaatac aattataatg aaaaaaatac
    45781 taaaactaga gctaagaaaa aacgataatt aactaaatac ataaagaaaa aaggaagaaa
    45841 aagtaatgat agaataagat tatctcaatt actatataaa accactttaa aaaattcaaa
    45901 atttattata taataataat atgaaatcct gaaacatacg ataaggcttt tttaaattca
    45961 acctacaaat gaaatacggg agaccgtgtc tggtaaatta taacatgcct agttagtttg
    46021 gacgttaaag gttactggca agtcacccac ctgggagtgc ctagggtgtg aatttactta
    46081 gccaccggtg tttcgggaca aaaaaagtgc tactatttca aatagtagta ctttttttat
    46141 taatatgcat ttttctacta aatacgccta attattgata aattcaaaaa gcaagtaaca
    46201 attaagatta taaaagcata gtattaatta ggcttcaaaa agccaaagac ttaataagaa
    46261 tcgcttacag ggagggcaat gaaaaatgca agattataaa aaaaataaaa gaagaatgat
    46321 gaatcagcca atgtctacaa tgaatgaaga agaagtgtat acagatgaaa taaattcaga
    46381 agacatgaga ggttttaaaa aatcacacca tcataatgga tgtaatactg ataataagtg
    46441 tgagtgccat gatgattgca atccatgcaa cccatgtaat ccatgtaaac ctaacccatg
    46501 caatccatgc aaacctaatc catgtgatga caattgtgga tgccatgaca attgtaaatg
    46561 tgattgtgaa ccatgtgaaa tggattcaga tgaatgtttt gaaaacaaat gtggaccaga
    46621 atgctgtaat cctatatctc caagaaactt ctctgtatca aatgcagtgc catttgcaat
    46681 agaggctaat agaatatttg atactatgca attccaaaca tttacagatg caacaggacc
    46741 aaatggagag ccattaactt ttgaaacaga agtagtagaa gtatttggtt cagttccaag
    46801 tgcaggtcaa gcaagtgtaa ctatagaaaa aatatgctta agtaatgatg gaatcgttat
    46861 agacacagga atgacaactt tagaagattt cgatttagac ccattaggag atatagtagg
    46921 aagaaactgt gaaacaactt ttgaatttgc agtttgtgga gaaagaaact ctgagtgctg
    46981 tagacaagga aaaggcaaat cagtagctta taaacaaaga ggattaactg tagcagttcg
    47041 taatttagta ctagagctaa gaggtagatg tggatgtaca gagttcgttg cattagcttt
    47101 cccagcagtt agagcaggag gtggatgtaa gagaagagtt gattatgtag aatttacttt
    47161 taacacactt tcagcaccaa tatgcttgcc agctgacgga agagctgtta ctttaagaca
    47221 agaatatcaa actaacttaa ctgtagattg tataggaaaa tctatattaa aattagaatg
    47281 caacgaatgt tgtgaacctt tctatgaatt aattatacca aatgatatag atttagtact
    47341 ttgcttacaa gaaacagtta gcacattaat aagtgaacaa atagtagttt tagcatcacc
    47401 aaatccaatc caaccaagac ttgttgatac tttctctaaa gtatgtgatt tttcgcaatg
    47461 tggacctaat catggaagtg gaaagccaag ttgccacaga tagataggta gatatataga
    47521 cagtttaaat tataaataaa aatcatctaa ggaaggctac caaagtgtat aatttacatt
    47581 ggtagccttc acgtttttat aactagcgta tagattttag tgatttaaaa agcactatag
    47641 tatgtaatag acaagtaaag attgatacta tcgtcattgt gtatatgtat gcataaatat
    47701 taagtcctgg aattggaaga aatacatata aagctattag ttgaattaac atgccagtaa
    47761 tagtatttat acttgaagct aattcttttc ttattgaatg taaaatgcca gatagagttt
    47821 gatttaggga cataaatagt ggaactaaaa acatagcttt tagatattct cctgcaagtg
    47881 tatttttaaa tactaatata cataaatctt ttccaaagaa ataaaaaaat attgatgata
    47941 gtatgcctac aaataaagta agaagtatgg agtatttgat ttttttaatt acactcttac
    48001 gctttcttag agccatttct tgtgaaatag ttggtattaa atttacaata agcgctgaac
    48061 caacagtaaa aggtaaaaat ataaaaggca ttaccatccc actgacaata ccatacatac
    48121 ttaaagattg ttgataagtc attcctgata atgctaatct tgatggtatc atcatagaac
    48181 ttatagattg caaaagtatg tttgacattc tattacaagt tatgggaata gacattttta
    48241 atgtttccat agaagaatta taaaaatctt ttatgcttat aatataccta ttgtcaaatg
    48301 atgaatctcg ccataagcaa ataagcataa atataatatt actcaactca ccaatcgata
    48361 tacctaatag agctatataa caattcatag atttattatt tatgtacata acaagtaaaa
    48421 aaacaaataa tattttacca atttgttcaa tgatttgtcc aatagcaggg atttttacat
    48481 tctttatgcc atagtaatat cctcttagta cgtttgaaag agttattata actatagcag
    48541 gacaaacagc tagtataaat agatttaatt tagcatcttt taaaaattta agtgataaaa
    48601 aagaactatt gaaagatgca actatagata taattagtgc tacgaaaaat gatatatata
    48661 aagttgatat aaataaagca ttagtattgt gtctatcgtt taaagctttt ctctttgcaa
    48721 ctagacaact aagtgcagta ggtatacctg ttgttgtaac agctaagcaa atcatcaaaa
    48781 agttaaaaat catatgatag atacctaaac ctgtttcacc tagtgctctt gataagaata
    48841 ttttatataa aaaaccaaat attcttacaa taaaattgga tataaataaa ataactgttg
    48901 atagtactaa ataaggtact ttcaaaaaaa tcacctcctt atcttttaaa tatattcaca
    48961 aggaggtgta aaaatttata attttataaa ttctggtttc aatttattaa atttagatac
    49021 atatttaaat cccatatttt ttagtaatga atatatgtag tcaaactcac atgcaacttg
    49081 acttatatga tgtgaatctg aacctgtggt tatgatttcc cctcccaagt ctttgtacat
    49141 ttgaagtata tacttagatg gggttaggtc tggaagatta tatctataac aagaggtatt
    49201 tatctcgata cctttgccat cataaatagc ttgtttaaga gtttcttcaa ttatatcaga
    49261 aaatagtcta tcatctaaaa tagtgtcata aggtgcatac cttttaatca aatctaaatg
    49321 acctaagaca gagtaatctt tataattctt aacaatatta tataaataaa gatagtaatt
    49381 ttcataaact tcatgttgag ttttatcttt aaaataatta ccaaggtata agtccattgt
    49441 atctatagca tggatagaac atattataaa gtccaatgga tattgatgtg cttccttttt
    49501 gtatgtatcc attaattgag tttgaactcc aaattcaatt ccttttttta ttgatatttt
    49561 atctttatat ttgctttgaa gagtctctaa actcttaaaa taatcttcgt agacaattga
    49621 aaaagaatca tcagcatata catcatagtc aacatggtct gtgaaacaaa tttcctccaa
    49681 accgagttca atagattttt ttaccatttc ttccattgta gattttccgt ctgtagagaa
    49741 acttgagtgc atgtgatagt cgtaaaacat aaatatttcc cctttttata aaaattttgg
    49801 tattatatat acatactaaa taatatcaaa tatacataaa agcatcaata aaatataaat
    49861 acaatgagcg gtgataaatt tggaaaaata cagaatagat ttaaatgaga aaaaatcaac
    49921 taaatatata cagatattta atcatataaa agaattgata ataaataaag agttagtaga
    49981 acatgaaaaa ttgcctccaa taagaaaact atcaaatttt ttacaagtaa ataacactac
    50041 tatagttaag gtatacgagc ttttagaaaa tgaaggatat gtatataaaa ttatagggag
    50101 tggtactttt gtatcaagtt taaattctta taaaagcggt atagataaca ggaaaaataa
    50161 gattattgtg caaagagaag atttaattca ttttgacaat gggaatccat ctaatgatat
    50221 gtttcctatc gattcattta aaaatgctgt aaatatggca ttatctaaag atggtagttc
    50281 aatatttgaa tatgatgaag gtcttggctc tgaagaatta agagaaaaaa tggtagagta
    50341 tctaagtgat ggaaatataa aaactactaa ggaaaatatt caaataatat caggtgctca
    50401 acaaggtata gatatagttt gtaaaggact tataagttat tcagatgttg tttttatgga
    50461 agaaccttct tacaatggag caattgaagt gtttaaaagt agaggtgcaa aaataatatc
    50521 tatacctatg ttagatgatg gaattgatat aggtatttta aaattaaagt tggaaaaaat
    50581 aaaaccaaga cttatataca ttatgcctaa ttttcaaaat ccaactggaa tatcttactc
    50641 aacatataaa aaaaagaaat tgatagaatt ggcagaagaa catgattttt atataataga
    50701 agatgatttt ataagtgatt ttgtttttga atcaaaggac aatagaacaa ttagaagtta
    50761 tgatgataaa aatagagtag tatatataaa aagcttttca aaaatactta tgccaggtct
    50821 taggatagga attgtagaaa tgccaaatga gttgttaaaa aaagttttat gggctaaata
    50881 ttcatcagat atatcaacac caggtttaat tcaaaaatca atgtattact atatgaataa
    50941 ttttgattgg aagaattatt tgagtcatat agagaagata tatactgata agtataaatt
    51001 ggcaaaaaac ttgattaatg acaaattgag tggtaaatta aaagttagaa aatcttgtgg
    51061 aggaataaac ttttttttag aattaccaag aggatataca tctcaagcat ttacaaattt
    51121 tatgttaaac aaaggagtgt caatgcttcc agggacttat ttttttgaca atctagtgga
    51181 tgatagattc tttaggataa atatagctcg tccaagcatg gaagaactag aaaagggaat
    51241 atctataata agtgataata tagatgagtt tttttgtgaa tataaaaaca agttagatat
    51301 aaaaagcaat aaattatttt attaaataaa tagaggtttt ttaggaggaa aaaatgtttg
    51361 acaagaagaa attagatagg attaatgaat tagcaaagaa aaataaagag ggaatccttt
    51421 ctgctgatga aatcaaagaa agagaaattt taaggaaaga atatttagaa aactttagag
    51481 cccactttag atcaagacta gatagtgtca aagtagtttc accagaagaa tatgagcaat
    51541 acatgaaaaa caataaaaat tagaacttag taggaggaaa atatgaactt aaagtacgaa
    51601 tttaagaatg cttgggattt tgaaagaaaa gaaaatacta ttgaacaaat tatgcaatat
    51661 tctagcaatt atatggagtt tttaagtaag tcaaagactg aaagactttc agtaaaagaa
    51721 attataaaat tggctaaaga aaataactat atttcaatag atgaagctat ggaaaaagga
    51781 agcataagtt gtggtgataa aatttatgtt ataaataaag agaaggcagt agcacttttt
    51841 gtaataggta aaaattatat agaaaaaggt atgaagatta taggaagcca tatagattcg
    51901 ccaagattag atttaaaacc aaatccactg tatcaagaga gtaatctagg tttttttaag
    51961 actcattatt atggtggaat aaaaaaatac caatggacgg ctattccact tgctttacat
    52021 ggtatagtta tattaaatga tggaacaaaa gtggacatat ctattgggga agaagatagt
    52081 gacccagtat tttgtgtaac tgatttattg attcatttgg ctggagacca aatgcaaaag
    52141 aaactatcag aaggaattag tggagaagct ttaaatatat taattgggaa tatgccttta
    52201 gaagatgaag aaaaagaacc tataacagca aatatattaa agattttaaa tgagaaatac
    52261 aatatagttg aagaagattt attaagtgct gaaattgaag tagttccagc tggtaaggct
    52321 agagatttag ggcttgatag gtctatggtg ttgggatatg ggcatgatga tagggtatgt
    52381 tcatatgctg ctgtaaaagc tatactagaa actgaacaac cagaatttac ttcagttgca
    52441 ttatgtgtag ataaagaaga aattggttct aaagggaata caggtatgca ctcaaagttt
    52501 tttgaaaata ctgtggctga actgattgct ttagaaggag attattgtga tattaaagta
    52561 agaagagctt tagcaaatag taaggtatta tcagctgatg tttctgctgg atatgaccca
    52621 aattttggag aagcatatga aaagagaaat tcggcatata tgggaaatgg agtagtttta
    52681 actaagtata caggttcaag aggaaagagt ggatgtaatg atgctaatgc tgaatttatg
    52741 tcagaagtaa agagaatttt taataaagga aatgtagtat ggcaaactgc tgaacttgga
    52801 aaagtagacc aaggaggagg cggaactata gcccatatat tggcaaatca aggtgcagag
    52861 gttatagact gtggtgttgg agttttaaat atgcatgcac cacatgagat tgtctctaaa
    52921 gtagacatat atgaaatgta taagggatat aaggcatttt ttaatataaa tttataagta
    52981 aaaatataaa tgtaataagt gaataaaggc tgttgtataa acaatttaat ctgttgtaca
    53041 acagtcttat ttttatgtaa aaatagcaat ttgtcacact agagaaaata aaagaaaata
    53101 ctgtcaaatt aaaaattatt ttaaaaaaaa ttgacaacga tttcatcttg ttataatatg
    53161 taataaagaa cttgttatat aatgttataa aaatgttaca tagggaggtg agcaaaatgg
    53221 atgaaaagag acaaaaaaaa gaaatggatt tagaagtaaa ttcctttgtt cctttatatc
    53281 aacaactata tgacaacata aaaaaacaaa tagcatctgg catatataaa ccaggagata
    53341 aacttccatc tgaaggagac ttatgtaaag aatttaatat aagtcgtata actgtgagaa
    53401 atacgacttt tttatataaa atagcaaaat aacagtgttt gagcaaaaaa aaagaatgtt
    53461 ttttatcgtt ttgccacctg tttgccacca taactttttt cggtggcaaa ttattgtaaa
    53521 atgccctcca aaatatctat tgtttcactt tccattttac ttgtaacatg tgaatatgtg
    53581 tccatagtgg ttgataattg actatgacct aatctttgtt gtatatattt tacattagct
    53641 ccattttcta ataataatgt ggcatgtgta tgtcgcaagc aatgaaaatt aaagttaata
    53701 tttagtttct tgttaatagt tcttatagca gcgtcaatat tgttgtgatt tacaaatgag
    53761 ccatcttttt ttctacaaac ccaatcatac tcagtttctt tataccattt tccaatttta
    53821 attttttgtt ttttttgatt caatttttcc tcttttaata tcctagacaa agtatcacct
    53881 attttaatat ctcttattga tgtttttgtc ttaggtgatg ctaattcaaa ttctgaaact
    53941 tttctcttta ttaaattttt tctaactttg attatattat tatctaaatc aacattatcc
    54001 caacaaagac ctaatatttc tccttttctc atgcctgtat gaaaccctat aagtagagga
    54061 atatagatat ttgtattttt aggatatatt tctagtattt tattgaactc atctagtgtt
    54121 atagtcttgt tatctgactc attttttacc tttaaaacat tttttggtat actggcatat
    54181 tgaacaggat tttccttaat gagtttgtaa gggtaaacag cagattttaa agcagcattt
    54241 aatacaacat aaatcgcttt taaaactcct tttgtgtagt gtttttcttc tccgttttgt
    54301 gtgtatgtct cttttgattt attatttaaa aattcttgaa taatagctgg atttatagat
    54361 tttagcttac atttaccaag tctaggttct atatgatttt caattaaatt tctataactt
    54421 tcctgagtat tgtatttgca attaagaagt acatactctt tgtaccaaaa gttaagatag
    54481 tctgataaac tcatatttgt ttcatcaaac actataccag cattttcata ttcatttatt
    54541 gcatcacgga gcgatttttc agcttctttc ttagtgtttc caccaactct ttctaccttt
    54601 tttctcttgc catctactat acctgcatca aagtagtaat accacttctt tccacgtttt
    54661 cttacgccgc ctttcataaa atctctcctc tcaaaagctt tttttatgta attatataat
    54721 aacatatatc aatttaaata aaataaataa aaaagactat aagaaacaaa gttttatgtt
    54781 tataattaat agtctttttt atttagatac atatttaatg ttttttatca cgtgattcca
    54841 gcactttttc tgccaaataa acaactattt tttcatactc aatatcagtt tctaaagaaa
    54901 agtcaacaat agcaggtatc gtcatatctc ctgcatattt attacctaac caattttcaa
    54961 ttaattccaa ttcttctttg cttaattcaa attttttctt tttattaaaa cttaagttca
    55021 atttattcac ctcaaataat attatatatt aaaaatagta tttgatagaa acattcgaat
    55081 tatttatgta attttctttt tttaatatat tcatcagcaa aataatttac taaatatttt
    55141 tcctccaatc ctaaagctat ttctaattca ataagagcag ggatagttaa atctttattc
    55201 tcattatttt ccaacctaga aatttgactt ctgtggcaac caactctttt tgctaactct
    55261 atttgtgtta atttcttctt ttttcgtaac tcttttaaca tatatttaac ctacctttta
    55321 gataatttta tatatgttag tttgtgtaat ttcttgtaat aaatgtgcaa tattcgcaca
    55381 ctttttgttg gaaatttgtg ctagaatgta gttaagaaat aactttatct aga
//
LOCUS       DAEPKC010000012        54233 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.012, whole genome shotgun sequence.
ACCESSION   DAEPKC010000012 DAEPKC010000000
VERSION     DAEPKC010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 54233)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54233)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54233
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.012"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            157..996
                     /locus_tag="KR294_000836"
     CDS             157..996
                     /locus_tag="KR294_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HBH0238943.1"
                     /translation="MLDINSFLNGFFNIILRMSIYDLIDISIVAYIFYKIFMFIKDTR
                     AEQVFKGIIFLLLATQLSNTFKLHTVYWISLKALDYGVIAALIIFQPEFRAGLEHIGR
                     AKFNLFGKNVNTSEETLNRNIEEIVEALYSLSRQKIGALIIMERETRISDIINTGTII
                     DAEISRQLLINIFIPNTPLHDGAVVIRDSKVKAAACFLPLTESKDLSKDLGTRHRAGI
                     GVSEVSDCITLIVSEETGGVSIAKAGKLYRDISRERMMNILRSNLKTNTETRSFFKGG
                     IFK"
     gene            993..2174
                     /locus_tag="KR294_000837"
     CDS             993..2174
                     /locus_tag="KR294_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0238944.1"
                     /translation="MINRLKNNTKIKIISFLSAIALWMYVMAVVDPEETKGFEDIPVS
                     ISNMSDLKDKNLVIYPDEKLTADVYIKGSLSKVQSVKKEDIHVYGTIEDPIQGQKEVY
                     LKANIPQGVTLEFKHDVLVVNLEKNIKEKRDIKVEVSGNSKRNINKIELSKEFVDVSG
                     PRTLVKEVKSVRANLDVGNETDDFSKKLQLIPLNSDGTKVEGVTLSSSFVTAKIELLK
                     EKIVPIRVSLNDNKDNDVLKNYKLSKEQVTIKGKKEDIDKISYIKTKPIDLADLANGE
                     EKEVSLEIPEGITLEDSSITIKLNDTKQLSAEFLYNAGDIELRNIPTNMDNPNVISDV
                     DIKVVVESTEDLSKLNKKDISLYIDLSQGPEEDSKYKIKYETTYQFKKINIEPNIVEV
                     E"
     gene            2478..3380
                     /gene="ptb"
                     /locus_tag="KR294_000838"
     CDS             2478..3380
                     /gene="ptb"
                     /locus_tag="KR294_000838"
                     /EC_number="2.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate butyryltransferase"
                     /protein_id="HBH0238945.1"
                     /translation="MRSFEEVIKFAKERGPKTISVACCQDKEVLMAVEMARKEKIANA
                     ILVGDIEKTKEIAKSIDMDIENYELIDIKDLAEASLKSVELVSQGKADMVMKGLVDTS
                     IILKAVLNKEVGLRTGNVLSHVAVFDVEGYDRLFFVTDAAMNLAPDTNTKKQIIENAC
                     TVAHSLDISEPKVAAICAKEKVNPKMKDTVEAKELEEMYERGEIKGCMVGGPFAIDNA
                     VSLEAAKHKGINHPVAGRADILLAPDIEGGNILYKALVFFSKSKNAGVIVGAKAPIIL
                     TSRADSEETKLNSIALGVLMAAKA"
     gene            3402..4481
                     /gene="buk"
                     /locus_tag="KR294_000839"
     CDS             3402..4481
                     /gene="buk"
                     /locus_tag="KR294_000839"
                     /EC_number="2.7.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="butyrate kinase"
                     /protein_id="HBH0238946.1"
                     /translation="MSKIFKILTINPGSTSTKIAVFDNEDLVFEKTLRHSSEEIGKYE
                     KVSDQFEFRKQVIEEALKEGGVKTSELDAVVGRGGLLKPIKGGTYSVSAAMIEDLKVG
                     VLGEHASNLGGIIAKQIGEEVNVPSYIVDPVVVDELEDVARISGMPEISRASVVHALN
                     QKAIARRYAREINKKYEDINLIVAHMGGGVSVGAHKNGKIVDVANALDGEGPFSPERS
                     GGLPVGALVKMCFSGKYTQDEIKKKIKGNGGLVAYLNTNDAREVEERIEAGDEKAKLV
                     YEAMAYQISKEIGASAAVLKGDVKAILLTGGIAYSKMFTEMIADRVKFIADVKVYPGE
                     DEMIALAQGGLRVLTGEEEAQVYDN"
     gene            4471..5148
                     /locus_tag="KR294_000840"
     CDS             4471..5148
                     /locus_tag="KR294_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH0238947.1"
                     /translation="MITNDKRIRIITGHYGSGKSEFAMNYVVKLRDMVSGKVAIADLD
                     VVNVYFRTREKKELMKSLGIQPIDSSINAPTLDLPAVSAEVMSPMVDHSYNSVIDLGG
                     DNVGARVIGRFSHLLKEGDYDMLFVINANREKTQTSEEVIQYIKEIEKSSKLKVTGLI
                     NNTHLIRFTTIDDVLRGQKVAKEVSEKCNIPIRYVACLENLVEQLPKDLEGEIFPIKL
                     YMREDWM"
     gene            5191..5406
                     /locus_tag="KR294_000841"
     CDS             5191..5406
                     /locus_tag="KR294_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBH0238948.1"
                     /translation="MAKGKVSFNQERCKGCGLCVEACPVKIIQLDSNVINKKGYNPAT
                     VFEMEKCIGCASCATMCPDVVITVERD"
     gene            5435..6514
                     /locus_tag="KR294_000842"
     CDS             5435..6514
                     /locus_tag="KR294_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate dehydrogenase subunit
                     VorB"
                     /protein_id="HBH0238949.1"
                     /translation="MAKILMKGNEAFGKAAIEAGCKYFFGYPITPQSELPEYLSRELP
                     KIGGAFVQAESEVSAINMVYGGAGAGARVMTSSSSPGVALKQEGITYAVGAEVPCVVL
                     NVMRGGPGLGSIQPSQADYFMSTRGGGNGDYRTPVFAPATVQEAVDMIMEAFDVADYY
                     RSPVMVVADGMIGQMMEPVEFRAPEKKRELPPKDWATVGTKGKRKPNVINSLYLEPEV
                     LEDHCWHLQEKFDAMEKNEVQYEMYKTEDAEFVFAAYGTTSRVVKSAIDILREEGIKA
                     GLIRPKVLWPFPFEAFNQIPNARNILTVEMSMGQMVEDVKMAVEGKLPVYFHGRPGGM
                     TPTPAEIVEKAKKIIAGELVAGGAR"
     gene            6514..7266
                     /locus_tag="KR294_000843"
     CDS             6514..7266
                     /locus_tag="KR294_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate oxidoreductase"
                     /protein_id="HBH0238950.1"
                     /translation="MAVVFKKTEGLQDTQTHYCPGCTHGIIHRLVGEVLEELGVLGDA
                     VGVVPVGCSVLGYKYFNCDTQEAAHGRAPAAATGIKRVHPENTVFTYQGDGDLASIGT
                     AEIVHAAARGEKITTIFVNNTTYGMTGGQMAPTTLVGQRATTAQSGRNAETQGYPIRV
                     SEMLATLTGAVFVERVAVDTPAHVRQAKKAIKKAFQVQQAGLGFGIVEVLSTCPTNWG
                     LAPNDALQWLRDNMIPYYPLGNFKNVEVEEVK"
     gene            7267..7824
                     /locus_tag="KR294_000844"
     CDS             7267..7824
                     /locus_tag="KR294_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase family
                     protein"
                     /protein_id="HBH0238951.1"
                     /translation="MSTARVICAGFGGQGVMSMGQLLTYAGMLEGKEVSWLPSYGPEM
                     RGGTANCAVTVSNEPVGSPLITDDATAAILLNIPAFEKFKDDVIPGGKIIVNSSLIKE
                     KVDRTDVDVYYIPANELAAELGNDKVANMIMLGAYLKVSDTVDIESVLEAFKKVFGPR
                     KEKFVPLNREALQKGMDATCSKATN"
     gene            7994..9340
                     /locus_tag="KR294_000845"
     CDS             7994..9340
                     /locus_tag="KR294_000845"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HBH0238952.1"
                     /translation="MRKYFGTDGVRGVANTELTCDLAYKLGRAGGFVLAQGDHRVKVV
                     VGKDTRISGDMLEASLIAGLMSVGCDVITVGIIPTPAVAYLTRKYGADCGVVISASHN
                     PVEYNGIKFFNKNGYKLDDEIELKIEEYIDDIDKIDCLPIGENVGRKLHEHCAQRDYV
                     DYLKSIISTDFKGLKVVLDCANGASYKVAPIVFDELGASVISINSSPDGNNINYKCGS
                     THPEQLQRAVLEHNADLGLAYDGDADRLIAVNEKGQIVDGDHIMILSALNLKKNNKLA
                     QDTLVVTVMSNIGLTIAAKENGINLSTTAVGDRYVLEDMVKNGYNLGGEQSGHMIFLD
                     YNTTGDGVLSSLILANIILQEKKPLSEIASIMSQYPQVLVNATIKNENKNKYMEYPEI
                     KTEIERIESILDGNGRVLIRPSGTEPLVRVMLEGKEEGQIKELATNLANLIQEKLS"
     gene            9607..11439
                     /gene="glmS"
                     /locus_tag="KR294_000846"
     CDS             9607..11439
                     /gene="glmS"
                     /locus_tag="KR294_000846"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003401499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HBH0238953.1"
                     /translation="MCGIVGYLGSRKAAEVIVEGLSKLEYRGYDSAGVAVNSSNEKEL
                     NIRKFKGRLSVLAEDLEKNPIDGNLGIGHTRWATHGEPSDVNSHPHFNQAKTIAVVHN
                     GIIENYMEIKEELISEGVKFESQTDTEVIAHLVDKYYEGNLLDAVYKTISKLRGAYAL
                     GVICKEHGNELVAVRKDSPLVVGVGEGENFIASDIPALLKYTRDVYFLENGEVVHLKD
                     ENVTVYDSNRNLVEKEVFHVTWDVEAASKGGYDYFMSKEIHEQPTGVRETLERRLDDN
                     GNIILDSINISKEDLEKINKVYIVACGTAYNAGLLGKYAIEKFVNIPVITDIASEFRY
                     SDPFVDENSLVILVSQSGETADTLAVLRDSKAKGARILSITNVVGSSIARESDDVFYT
                     WAGPEVAVASTKAYTTQITSLYMIALDFAIKKGTITREFYDSMISKMKEIPSKIQEIL
                     DNEEYIKEVAKTVVSSEHAFYLGRGIDYSLAMEGSLKLKEISYIHAEAFAAGELKHGT
                     IALIEKGTPVIAIATQEKLFEKMVSNMEEVRARGAYVVAIAQSHNKDVEKAADKIIYI
                     PNSDDILSPILAVVPMQLLAYHVSVLRGCDVDKPRNLAKSVTVE"
     gene            11890..13185
                     /locus_tag="KR294_000847"
     CDS             11890..13185
                     /locus_tag="KR294_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate sulfurtransferase"
                     /protein_id="HBH0238954.1"
                     /translation="MTNDFKKEKKEDYFVNLKAISTEVLQEKVQDNAWVIVDTRLNDA
                     YNGWKLDGVKRGGHIKGAVDFSANWLSVYSDRKDEVLEQALKTKRIDLDKNIVLYDAN
                     GKDALVVADYLSKKGYKYLYKYDIKQWADNENLPMERYKNYQMIVPAFIIKDILDGKI
                     PETFEDSKNIKMIEASWGEESYTKGHIPTSVHVNTDIIEPPPTWMLDNDDNLIKFALD
                     YGLTKDDTVIVSSSTPMASYRLAVILRYIGVKDVRVLNGGTNSWLSAGYELEFTSNPK
                     HSCTNFGADIPVNSQLVVTTSELRQKLKEKNKFILVDNRTWDEHIGKVSGYTYYDKKG
                     RIPGALYGHSGSDSVSLEEYRNIDNTMRNKYEILEMWDKENIDVNRQLIFMCGSGWRA
                     AEVLTYANVIGVENTSLYSDGWMGWSLDNSNLIEVGEHK"
     gene            13635..14372
                     /locus_tag="KR294_000848"
     CDS             13635..14372
                     /locus_tag="KR294_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YwmB family TATA-box binding protein"
                     /protein_id="HBH0238955.1"
                     /translation="MKRVKLAISFFILMIIGMTISYADTSINTKYNRLSKALEISEAN
                     FKFYNVKINSVINHNLSNKEFHNIFIEIINNLKLDKKGINWNQKGSGDKIQLCATIKG
                     SDKEISIKGINKNNKESYIVVDILDNKVYKHKEVIYSNVENVLNKYSSQVDVSACIVG
                     EYTKRLQNNKYDDILQKILYNMSAKQIDEVKDVNFLSITAYSKVLNDYELEYLGEKIN
                     LNIGIKYNEDDGRTLIYIATPIIKLDY"
     gene            14393..15646
                     /gene="murA"
                     /locus_tag="KR294_000849"
     CDS             14393..15646
                     /gene="murA"
                     /locus_tag="KR294_000849"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HBH0238956.1"
                     /translation="MAKIIVKKSNPLKGSVKIDGAKNAVLPIIAATLLANGKSTLNGV
                     PNLRDVHVISDLLRHVGAEVEYKENTLTVDASNIKTCEAPYELVRKMRASFLVMGPLL
                     ARFNSTKISMPGGCAIGTRPIDLHLKGFKALGAKIEMDHGFVEAATEKLVGNKLYLDF
                     PSVGATENIMMAASLAEGTTIIENAAEEPEIVDLANFLNEMGADVKGAGTNTIKIKGV
                     KELKGAEHNVIPDRIEAATYMVAAAMTKGDITVENVLMEHLKPVVAKLREAGCEITEM
                     DNSVRVVGPKVLKPIDIKTLPHPGFPTDVQAQFMAMLTVANGTGVVIETVFENRFMHV
                     AEFNRMGANIKIDGRSAVVNGVDELHGAAVNATDLRAGAALILCGLIAEGETQIGEIY
                     HIQRGYVDIDKKITALGGQIEIVED"
     gene            15733..16797
                     /gene="spoIID"
                     /locus_tag="KR294_000850"
     CDS             15733..16797
                     /gene="spoIID"
                     /locus_tag="KR294_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein D"
                     /protein_id="HBH0238957.1"
                     /translation="MKNPLVVLLGFVTCSVLVPSLITLVSYKNVELTEKAESPVSINK
                     TIKKSDIEDKGNKEEKNTVNYETVNKKAPIINVYNHITGKTEKMDMENYLCGVLAGEM
                     SSEFDIEALKAQSVAARTYVVYKQEHGKSSKHKNAVVCTDYKHCQEYKSYDTLKKLNG
                     EEWIKNKYSKIQEAVRGTKGQIITYNDKAILPLYFSTSSGKTENSEEVFSAKYPYLKS
                     VESPYDKYSPKFASTLKISNTDFVKSLRRAYSTIVIDVNNLSKQVSITKRSDAGTVEK
                     IKLGNKELTGKDIRTVFKLNSANFDIKFGEGYIDFVVKGYGHGVGMSQWGAEGMAEEG
                     YKYYDILSHYYTDTKIKDIY"
     gene            16863..17531
                     /locus_tag="KR294_000851"
     CDS             16863..17531
                     /locus_tag="KR294_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M23 family metallopeptidase"
                     /protein_id="HBH0238958.1"
                     /translation="MKKKLLEKDGFYLSLFVCVCLLAVGGVWFTNNNVDKLASNKGIM
                     ENANKDSEEEIHLIEKDKKDAIPTATDSKQNLEKAKSKEENKSSTTKLNYIGDKVIRG
                     YSEKEPSYSKTLDVWETHKGVDISCTKGKEVKSLLNGIVVDVFNDEEYGQSVKIKSDN
                     NIVVVYSNLDKNVSVKKEQKVTEGQSLGTVGSTSQIESEEGIHVHLEAYSGEKSIDPM
                     SLIK"
     gene            17629..17889
                     /gene="spoIIID"
                     /locus_tag="KR294_000852"
     CDS             17629..17889
                     /gene="spoIIID"
                     /locus_tag="KR294_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation transcriptional regulator SpoIIID"
                     /protein_id="HBH0238959.1"
                     /translation="MRSHIEERAIVVAKYILEKNTTVRQTAKTFGVSKSTIHKDVTER
                     LKEINPSLAKEVKNVLDKNKSERHIRGGLATKLKYEKEHKKM"
     gene            18086..19105
                     /locus_tag="KR294_000853"
     CDS             18086..19105
                     /locus_tag="KR294_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein"
                     /protein_id="HBH0238960.1"
                     /translation="MAGADIGIDLGTANVLVYVSGKGIVLEEPSVVAIDNRTDSVLAV
                     GEEAKKMIGRTPGNIVAIRPLRDGVISDYDVTEKMLKSFIDKIVDKKGFGRFFMPRIM
                     VCVPTGVTEVEKRAVEDATRQAGAREVYIIEEPIAAAIGAGVDISQPNGNMIIDIGGG
                     TVDIAVISLGGAVVSESIKVGGDRFDDAIVKYMKKQHNLLIGERTAEKIKFEIGSAFK
                     REEEKYMKITGRNLITGLPSSITINSTEMLEALRECVEQIVVATHAVLEKTPPELAAD
                     IGDVGIIMTGGGSLLYGLDKIIEQRTGITVTIADEPLSCVAKGTGIALGSIDLLETGG
                     SFKRK"
     gene            19121..19549
                     /gene="fabZ"
                     /locus_tag="KR294_000854"
     CDS             19121..19549
                     /gene="fabZ"
                     /locus_tag="KR294_000854"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HBH0238961.1"
                     /translation="MLNIDEIKKLIPHRYPFLLVDKITELEVGKRAVGIKNVTVNEPF
                     FQGHFPEYPLMPGVLIVEALAQVCGVAMMSVEENKGKLGVFAGIDKVRIKREVRPGDT
                     LTMEVEMTTLRRNIAKADAKAYVGEELVCKGELMFALVEK"
     gene            complement(19660..20169)
                     /gene="yyaC"
                     /locus_tag="KR294_000855"
     CDS             complement(19660..20169)
                     /gene="yyaC"
                     /locus_tag="KR294_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore protease YyaC"
                     /protein_id="HBH0238962.1"
                     /translation="MYLAKVNYSDDDVIQMLSSVLKTIINENTIVVCIGTDRAIGDTL
                     GPLVGTILKNSNFKYPVYGTLDNPIHALNIYESLDTIKNTHIQGNFLAIDACLGSQSN
                     IGNIQIREGPILPGKGVGKKLPQIGNYSIVGIVDKIDENNKLSFNNIRLSFILDLAET
                     IALALLVST"
     regulatory      20358..20461
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            20597..21790
                     /locus_tag="KR294_000856"
     CDS             20597..21790
                     /locus_tag="KR294_000856"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HBH0238963.1"
                     /translation="MARHLFTSESVTEGHPDKICDQISDSILDALLEKDPQSRVACET
                     TVTTGLVLVAGEISTSAYVDIPKLVRETVREIGYTRAKYGFDCDTCAVITSIDEQSGD
                     IAMGVDEGLESKTGEEIEEEIEKVGAGDQGIMFGFACNETPELMPLPISLAHKLSRRL
                     TEVRKTGLVDYLRPDGKTQVTVEYEGSKAVRVHTVLISAQHCETVSNDKIREDLINHV
                     IKEVIPAELLDEDTKIYINPTGRFVIGGPQGDTGLTGRKIIIDTYGGYSRHGGGAFSG
                     KDPTKVDRSAAYAARYVAKNIVAAGLADKCEIELAYAIGIARPLSIFIDTFGTGKVSE
                     EKLVELVNKHFDLRPGAIIRDLDLRKPLYKKVAAYGHFGRTDIDLPWERTDKVEQLRK
                     DALGE"
     gene            22105..23202
                     /locus_tag="KR294_000857"
     CDS             22105..23202
                     /locus_tag="KR294_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0238964.1"
                     /translation="MSGKVNIKTVISFAGAYVATVIGSGFATGQEILQFFTFYGYAGI
                     IGGIISMVLFSWFGAEVIDKGRELKLKEPIKIYQVYCGKYLGTFFEWFGPLFLFGTLV
                     IMIAGAGATLSEYYGLNPYVGRIGMTIVSLITVSLGLTRLSKILGNIGPIIIIFTLLV
                     GAISLFSNIDALSNAGNMVDSLNIKTATSNGYFSGVLYTCYNVIIVITFLTGMGASAV
                     NKKDAVWGGIVGGVALMAAAIMMNLALLSDIGNIYTKEIPALYLADKISPIIGILFSV
                     VLLLGIYTTAVPLLWSVTNRFVEDDHPKFKIITIVVSILACIGGLLPFDKLVGTLYPY
                     TGYMGILILLCMLYRRITKTEGYKENKSEIS"
     gene            23466..25685
                     /locus_tag="KR294_000858"
     CDS             23466..25685
                     /locus_tag="KR294_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HBH0238965.1"
                     /translation="MEKLEGMISEIVFKNEDNGYTIAHLVNENDEIVVVGCMPTLAIG
                     ESIEVEGKWVNHKIYGTQFEVNSFMPVTPSSLEGIYVYLSSGMIHGIGEKMAKRIIDK
                     FGVDTLEVIQNSPEKLQEVEGIGSKKVKQIVKSYEEDRELRNIIIQLSPFGITPNYCL
                     KIYKKYKSSAIEVINKNPYQLAEDIRGIGFKVADSIANKIGIDKNSKDRICQGILYTL
                     NKSLSNGHTYLPEHVLIQDSEKLLELNGEIIKECVMMLVYNQKIHVEKVNNENLIYLM
                     PYYLAENGVCSQIVKLSQYEFEDLKIDIDNEINVLEEDKKIKLAEKQILAVKESVNSG
                     VLIITGGPGTGKTTTINAIIDIFENNGKSVTLAAPTGRAAKRMSETSNKEAKTIHRLL
                     EMGFSTDDDLTFFKDEEDPINSDVIIVDEVSMVDIILMYNLLRAIKLGTRVILVGDSD
                     QLPSVGAGNVLKDMINSNIINVVKLNEIFRQAQESMIIVNAHKINNGEPLYLNTKGKD
                     FFFIRKSTNEEILNEIIGLVNERLPKFYKVDKLKDIQVLSSMRKGELGVTNLNIELQK
                     YLNKKEKFKVEESFSKRLFRVGDKVMQVKNNYTKKWETEDQKESGEGIYNGDIGYVYH
                     IDKDKKTIYILFDQTKIVSYLYDELDEIDHSFCTTIHKSQGSEFPVVVLPIAWAPPML
                     LSRNLLYTAVTRAKKLVVLVGDVKYLEYMIKNNRVNQRYSNLGYKLNKFKQEGLLIE"
     gene            25688..26470
                     /locus_tag="KR294_000859"
     CDS             25688..26470
                     /locus_tag="KR294_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HBH0238966.1"
                     /translation="MKICNDNFIKNFKNMINKCLDFIYPENISCIICDKSIKKTNTYS
                     ICKSCFKEMNFIQDGCMKCGKPIIRHSIEKEFIEECSYCFNKDFYFDKSISCIEYNDV
                     TKKIVLGLKYNQKTFMAKYIAQIMKEKLYLENIKFDYILFVPLHKKRLNKRGFNQAQK
                     IAFNLSKIVNIPLLDCISRKKYTRMLYKLNKKERKEELKNVFVVKDNVKLINNKNILL
                     IDDIFTTGLTTNEISKLLKLSGANKVFVLTLLTKANDNYIME"
     gene            26802..28715
                     /locus_tag="KR294_000860"
     CDS             26802..28715
                     /locus_tag="KR294_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBH0238967.1"
                     /translation="MICLNKRQENLLTTLLLKEEFINVNKIANDFECSERTIRNDCKY
                     IDEWLSTFCNAYIKRKPNIGIKFSGDGTDKILVNQKLRGEVKRVNSELHKQVEILNLL
                     LCNNKKVTLNDLSNKLYINKNIVREEISKLSVALNNYNLNVSTKKGSGIYIGGDEKDI
                     RIMLVSFLFKYIDKYRLNIDEIEYFHIVDIIIVKNIMFTIEEDMDIRLTDISFKQLML
                     FLLINIIRIRLGNSLKVSNTKKELKLKMLILDIEDELKSNLSIVLNYEEKLFIESLIL
                     GMNKQINSSNIKKSLYLNEELASYTKKIINLVSEESGINFNNDILLYEQLICHLNVTM
                     HQMKSNVYLENPLLDNIKTKFCFLFTVISSSIEIELKGKQITEDEIGYLTLHFQTSLE
                     RKYSKRESNKKASIVCPFSFGVSMLLKVKIEKRFDNIKIIETLREEDLKRDNFNKTID
                     FIIAFQEYENIQKPIFITTPLFTDEDENKLKEFTNKIKEKDTSYKLMNRLMMSDYLIR
                     ELEHDDIYEAITYLTNLLIEKHYAEKEYLQSIITREKSYPTNVGKGILFPHGDMKYIK
                     QSVLCFARLKTPIRIRNGKDIKIILLLAYKKDDDRKVFRELFKEISNLTEDENMLDIL
                     SKCDIEKVKDILI"
     gene            28856..29164
                     /locus_tag="KR294_000861"
     CDS             28856..29164
                     /locus_tag="KR294_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBH0238968.1"
                     /translation="MEEIVLKIIIHAGNAKSMLYEALDYAKENDFKKADELIENANEE
                     ILKAHKVQTELIQKEAGGDKSDISILLIHSQDHLMTCMSERNLIKEMIMLRKEIQKLK
                     "
     gene            29188..29514
                     /locus_tag="KR294_000862"
     CDS             29188..29514
                     /locus_tag="KR294_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH0238969.1"
                     /translation="MKRKVYLFCSFGMSTSLLADKMQKVADEHNLPIEVEAFPIAEID
                     KIVEEKNPDCILLGPQVKYMLKELKPKFEAQGKLIDIINEVDYGTMNGEKVLKLAIKL
                     IKSKQA"
     gene            29553..30887
                     /gene="celB"
                     /locus_tag="KR294_000863"
     CDS             29553..30887
                     /gene="celB"
                     /locus_tag="KR294_000863"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HBH0238970.1"
                     /translation="MNRLERILMPLAEKIGKNKLLIAIRDGFLISSPLLIIGSLFLLV
                     ANFPIKGWNEFVGQIFGSDWAVKLQQPTVATFEVMTLLAVLGIGYSYAKQIDVDPIAS
                     AAVAIVAFFIITPFVIPYTPEGTESVYMVTGIPLGWMGSKGMFVGMITAITSVKLFAA
                     VVKKGWTLKMPDGVPPTVSKSFAALIPSAIVMVVFFLVKIAFEATPYGSIHEFIFKFL
                     QMPLLKLGNSLGAMAIAYIFLHLFWFFGINGSSVVGAVYNPILKILSAENLAAFQAGS
                     KIPNIITGQFQDMFATFGGAGSTLSLVIAMLLICKSKRIKSMGKLSILPGIFGINEPL
                     IFGLPIMLNPILLIPFAIVPTINIIIAYFCMSAGLVPLTNGVQLPWTTPIIFSGFLTT
                     GWQGAVLQVVLLILGIFMYIPFIKMLDKQYLREENATVEEEDDDISFDDLVL"
     gene            30898..31416
                     /locus_tag="KR294_000864"
     CDS             30898..31416
                     /locus_tag="KR294_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/betaine/sarcosine/D-proline family
                     reductase selenoprotein B"
                     /protein_id="HBH0238971.1"
                     /translation="MKKIVMILDQIQAGAGGKEKSNIPPAGKSSPLGPGIMMEQFLNE
                     SKVIATLFCGDEFFVNNEEEVTSKMIAMVKKLNPDVVICGPSFNYENFSKMSAILSKN
                     INDKTDIPAFAAMSEENIDVINEYKNDICIVKTPKKGGIGLNDSLNNICKLAKAIANK
                     EDITLMKEEFCY"
     gene            31512..32471
                     /locus_tag="KR294_000865"
     CDS             31512..32471
                     /locus_tag="KR294_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase"
                     /protein_id="HBH0238972.1"
                     /translation="MWGMIATWRMALEGITEASEHLEKGMEAGDAVELAVRRVEDYPF
                     YKSVGYGGLPNENCEVELDAAFMDGNTLDIGAVAGIRDYSNPVSIARKLSYEKVNNFL
                     VGIGAEDYAHKNGFERKNMLTDRAKLHYKKRKKETLDKGLSPYAGHDTVGMISLDKTG
                     KMCAATSTSGLFMKKRGRIGDSALSGSGFYVDSSIGGATATGLGEDLMKGCISYEIVR
                     LMKEGKHPQEACDIAVNELDKQLIKRRGKAGDLSLVAMNNKGEWGVATNIADFTFSVV
                     TKEESPTVYISNRVDGKTIHKVISNEWMEAYEARIKAPIEVSE"
     gene            32520..33572
                     /locus_tag="KR294_000866"
     CDS             32520..33572
                     /locus_tag="KR294_000866"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HBH0238973.1"
                     /translation="MNIISNKIDELKEDLLSDIIDIVKIPSVKGESENGFPFGEKVGE
                     ALNKALEISEKLGFKVRNLDNYIGYAEHGDSDDYVCVIGHVDVVHEGDGWKHQPYKGE
                     ETNGRIYGRGVLDNKGPIMSALYGLYAIKELNLKLDKRVRIIFGTNEESGFEDIPYYL
                     EKEKAPIMGFTPDCKYPVVYGEKGMAKIRIKSKINYEEDVYLGFIENMSENVLVTYKE
                     LNIENSDTILDIKVKYDFSYKLKDVLDEIKASFPNSIDIEVISNFNPVYFDKESNLVK
                     KLQLAYERVTSLDGTPVTTNGGTYAKVMPNIVPFGPSFPGQKGIAHNPDEYMDIEDII
                     LNAKIFANAIYELAKE"
     gene            33575..34249
                     /locus_tag="KR294_000867"
     CDS             33575..34249
                     /locus_tag="KR294_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HBH0238974.1"
                     /translation="MLEIIGMSVEDAKIIEDCGADRIELVSALTEGGLTPSFGLIESV
                     VNSVKIPVNVMIRHHAKSFVYSKEDISIMQKDISVVKEIGANGVVFGVLDKNNSIDEK
                     NLNVLLKCCDNLDVTFHRAIDESNTIDSVKILKDYDKITNILTSGGKGSIVDNIQMIK
                     NMMLSSNHIKILLGGGLNFNNIEKIKELTKASNFHFGTAIRINNSPFEDIDRQKLKQL
                     VNIISR"
     gene            34802..35353
                     /gene="raiA"
                     /locus_tag="KR294_000868"
     CDS             34802..35353
                     /gene="raiA"
                     /locus_tag="KR294_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HBH0238975.1"
                     /translation="MNIIISGKQIELTDAIKNKIETKLSKLDNYIHPDTDVKVTVSAR
                     KARQKIEVTIATVNGPIIRAEDMQENLYTAIDVVYDKLSKQLKKYKKRLQDKHKDNKS
                     IRFQDAEINLADEQEDYGDENQELVIQRRKKFSVKPMSEEEAVLQMELIGHDFYMFKN
                     IDSDEIAVVYKRNNGGYGIIEHE"
     gene            35485..38160
                     /gene="secA"
                     /locus_tag="KR294_000869"
     CDS             35485..38160
                     /gene="secA"
                     /locus_tag="KR294_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HBH0238976.1"
                     /translation="MSFMDNLFNMADKKELKKFNKTVDIIDSLEPKFESMADSELKNM
                     TNIFKERLANGESIDDILPEAFAVVREVSKRVLGLRHYRVQMIGGIVLHQGRIAEMKT
                     GEGKTLVATAPVYLNALTGKGVHVVTVNDYLAKRDRDQMAKIYEFLGMSVGVIIHGQN
                     PKVRKEQYDCDITYGTNNEYGFDYLKDNMVIHKEQRVQRGLNYAIVDEVDSILIDEAR
                     TPLIISGPGDKSTHLYSDANTFVLTLKPDDYELEEKDKAVSLTASGIQKAEVYFNVDN
                     ITDISHTELYHHINQALRAHVIMKKDVDYVAKDGEIVIVDEFTGRLMFGRRYSEGLHQ
                     AIEAKEGLKIQRESKTLATVTFQNYFRMYKKLSGMTGTAKTEEEEFKAIYKMDVFQVP
                     TNKLMIREDLPDCVYKSEIGKFNAVAQEIIERHKVNQPILVGTVSIEKSELLSQILKK
                     KGIKHEVLNAKHHDKEAEIIAQAGRLGAVTIATNMAGRGTDIVLGGNPDFLTKREMRR
                     NGFKEEIVNRVDTPIEGIPVKGNEILFEAREEYEKLFEKFKQQTQEEQKQVVEAGGLA
                     IIGTERHESRRIDNQLRGRAGRQGDPGSSRFYIGLDDDLMRLFGSDRISGIVDKIGLE
                     EDMPIEHRILSKSIEGAQKKVEGKNFGIRKHVLQYDDVMNKQREIIYAERKRVLEGED
                     LQEQIQSMTHSIIEEAVTLYTQDKGFDEEGFKEHMYNLFLPKGSIEIPEIEKLNPVEI
                     TEKVYEIAMKIYTSKEEQVGYERMREVERVILLQAVDNHWIDHIDAMDQLRQGIGLRA
                     VGQQDPVIAYKMEGFDMFDEMNKHIKEDTVRYLFNITIETPVERKAVVDVENLSSPSD
                     GTLPTSKTVKKDEKVGRNDLCPCGSGKKYKNCCGR"
     gene            38175..39282
                     /gene="prfB"
                     /locus_tag="KR294_000870"
     CDS             join(38175..38249,38251..39282)
                     /gene="prfB"
                     /locus_tag="KR294_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_153309863.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HBH0238977.1"
                     /translation="MLKLQEYRHSMEQMASNLEELRVSLDIASLMKNIQINEEKMNKQ
                     DFWNDNEVAQRVLQENKSLKETLEEYESLKSLLEDIEVLIEIGLEEDDDSVERDIEKS
                     IESMEEKLSEMKIKTLLNGEYDKNNAILSINAGTGGLDAQDWAQMLLRMYIRWSESKG
                     YKVKLLDIISDPEAGIKTATILVEGTNAYGYLKSEKGVHRLVRISPFDPSGKRHTSFA
                     SIDVTPELDENIEVEINPSDLKIDTYRASGAGGQHVNTTDSAVRITHIPTGVVVQCQN
                     ERSQHLNKDRAMRLLMAKLIELKELEQKEKIEDIQGKYSQITWGSQIRSYVFQPYKLV
                     KDHRTNAEFGNVDSVMNGNIDLFINEYLKMNKIV"
     gene            39426..41567
                     /locus_tag="KR294_000871"
     CDS             39426..41567
                     /locus_tag="KR294_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011010799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HBH0238978.1"
                     /translation="MDINQILKKEFNLRDEQINNTLKLIDEGNTIPFIARYRKEMTGE
                     MSDVTLREFYEKLMYLRNLQSRKDDVVRLIDEQGKLTDEITQNIEKAKTLQEVEDIYA
                     PYKQKKRTRATIAKEKGLEKLALSILENNLDNIEIEAKNYLDEEKEVLSIEDALKGAR
                     DIIAELVSDDAKIRKYIRELALREGMIVSKSATDEKSVYDMYYDYSEAVKSMPPHRVL
                     AINRGEKENFLKVKLEINNDKVLNYIINEYVNDKNFKNKEEIVSSIEDSYKRLIFPSI
                     EREIRNHLTEIAQERAISVFGKNVKSLLLQPPVKDKVVMGFDPAFRTGCKIAVVDKNG
                     KLLDYTTVYPTDPQNDVEGAKKVLKGLIEKYDIDIISIGNGTASRESETFVSEMIKEI
                     DNEVQYVIVSEAGASVYSASELANEEHPDINVSIRGAISIARRLQDPLAELVKIDPKS
                     IGVGQYQHDLNKKRLEEVLDGVVEDSVNSVGVDLNTASYSLLEHVAGISKTIAKNIIA
                     YREENGDFTSRAQLKKVKRLGPQAFTQCAGFMRILEGKNPLDNTGVHPESYDICKKMI
                     EIIGYSLDDVKNKNICEIDEKIKEIGLRELSEKLEVGQVTLKDIITEIKKPGRDPREE
                     GIKPILRTDVLKIEDIQEGMTLKGTIRNVVDFGAFVDIGIKNDGLVHKSEMSNSFVKD
                     PMSIVTVGDIVDVKVIGIDLNKKRVALSMKK"
     gene            41715..42881
                     /locus_tag="KR294_000872"
     CDS             41715..42881
                     /locus_tag="KR294_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH0238979.1"
                     /translation="MIFIKNGKINTITNGIIHGDILIDEGKIIEIGEDLIAPLDVEVI
                     DASNKLVFPGFIDAHTHLGLWEDGIGFEGADGNEETDPITPQLNPIDGINPMDRTFKE
                     AFEGGITSVCTTPGSANVMGGQCIAIKTCGKRIDKMVIKNPVASKIAFGENPKSCYGQ
                     DDKSPQTRMAIAALLRENLKKAEEYLEDIDMYESHDDEDCEKPEYDIKMESLIPVLRR
                     EIPFKAHAHRADDMFTAIRIAKEFNLKLTLDHCTEGHLIVDELVEEGFPVIVGPSLSE
                     RSKFELRNLTFNTAGILSNAGLDVCIMTDHPVIPVQYLPICAGIAVKHGMKEEKAIES
                     ITINPAKTLGIEDRVGSIEVGKDADLVIWDNSPLEIQSNVLYTIINGKVVYEKK"
     regulatory      42941..43058
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            43182..43787
                     /locus_tag="KR294_000873"
     CDS             43182..43787
                     /locus_tag="KR294_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBH0238980.1"
                     /translation="MQNTAKRGNMISTRTLVVMSILSAISYLLMFIQAPIPGIFPDFL
                     KIDLSDIPAIFGGMSLGPFVGFGIVVVKNVLQAITATTTGGIGEFANILIGGSYVMIL
                     CYSYKRSGDLKGVLIGFVLGTISMTIIGSLVNYFVMLPLYGQLMGLDAIIGLGSAINP
                     QVHDLFTFVIWMIAPFNVLKAVILSLVTLPLYKKMGNVIKK"
     gene            44116..45156
                     /locus_tag="KR294_000874"
     CDS             44116..45156
                     /locus_tag="KR294_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4116 domain-containing protein"
                     /protein_id="HBH0238981.1"
                     /translation="MNLSKKIKKLFLDDKGYYFNSNWKDIHIGIYNTKLGDSLKYITN
                     EYIENLERVKYDYRELKNIENQTDGMCILAIRQNYKALEYVKNQTEELCLEAIKYNYK
                     ALEYVKEQTEYICLEAIKKDCNALKYVRNKTERLIIKVIRHSSNIDVVSILKALETQT
                     RRICLEAIKKDGRCLAYVREQSEELCIEAIKQNYKALKYVENQTEKMCIESVRQNGMA
                     LQYVNKQTDKICIEAVKQDGRSLQFVNNKTEEICINAIRYLNKKYNIKDVLSYIDKYT
                     EDICIEIVRQNGKMLMYIKNQTEKMCIEAVKENYKSLKYVKEQSERICKEALKQNHKA
                     KEYVKIAIDDCI"
     gene            45295..45747
                     /gene="tsaE"
                     /locus_tag="KR294_000875"
     CDS             45295..45747
                     /gene="tsaE"
                     /locus_tag="KR294_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HBH0238982.1"
                     /translation="MAKIYLENENKTREIGYKLGKLLKEGSVICLVGDLGAGKTTMTQ
                     SLADSLGIEDYITSPTFTIINEYEGKIPLYHFDVYRIGSSDEMYDIGYDEYVNSNGIC
                     IIEWANLIEDILPKEYLNIELRYKDDGREMILTPKGEFYKEIVEELIK"
     gene            45747..46463
                     /gene="tsaB"
                     /locus_tag="KR294_000876"
     CDS             45747..46463
                     /gene="tsaB"
                     /locus_tag="KR294_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HBH0238983.1"
                     /translation="MKILGMDTSSMAASVAVVEDDNLICEFTVNNKKTHSQKLMPMIE
                     NMLSMSDLSIKDMDLLAVCIGPGSFTGLRIGMATVKAMAHVNNIPIIAVNSLESLANN
                     INFCDRKICCILDAQKNQVYSAKYKFENGEMIELDGVDVVEFDALVDEIVSTNEEFII
                     VGEAVYKYKDKLENIKNIKIPSPANNVSNAGSLCSLALNKYNKNIDVHTCYTINPMYI
                     RKSQAEVQYDEKMKRLNNGR"
     gene            46453..46929
                     /gene="rimI"
                     /locus_tag="KR294_000877"
     CDS             46453..46929
                     /gene="rimI"
                     /locus_tag="KR294_000877"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HBH0238984.1"
                     /translation="MEDNTKLIVDDIKIEEMTTEDIDEVFEVEKNCFEDYWSKESFRK
                     ELSNEVARYIVAKLNGKIVGYVGIWLILDEGHINNVAVHSDYRGKKIGDKLIKGIVDL
                     CKDNNIASMTLEVRASNKIAQNLYRKYGFKMGGIRKEYYSDNKEDAIIMWNQLKEV"
     gene            46935..47951
                     /gene="tsaD"
                     /locus_tag="KR294_000878"
     CDS             46935..47951
                     /gene="tsaD"
                     /locus_tag="KR294_000878"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HBH0238985.1"
                     /translation="MSDIITLAIESSCDETAASVLKNGREVLSNIISTQIETHKKFGG
                     VVPEVASRKHVENIDIVVQEALDKANIGFNDIDHIAVTYGPGLVGALLVGLSYAKALA
                     YTLNIPLVGVNHIEGHLSANYIEHKDLKPPFITLIVSGGHTHLVEVKDYGKYEILGKT
                     RDDASGEAFDKISRAMNLGYPGGPIIDNLAKKGNKHAIEFPRAYLEEDSYDFSFSGLK
                     SSVLNYLNGKRMKNEEIVVEDVAASFQEAVVEVLSTKALKAVKEKGYNIITLSGGVAS
                     NSGLRAKITELAKDSGITVKYPPLILCTDNAAMIGCAGYYNFINGKTHDMSLNAVPNL
                     KINQ"
     gene            48248..50956
                     /gene="hpdB"
                     /locus_tag="KR294_000879"
     CDS             48248..50956
                     /gene="hpdB"
                     /locus_tag="KR294_000879"
                     /EC_number="4.1.1.83"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate decarboxylase large
                     subunit"
                     /protein_id="HBH0238986.1"
                     /translation="MSQSKEDKIRSILEAKNIKSNFQNKENLSEFNEKKASKRAEDLL
                     DVYYNTLSTADMEFPYWYNREYRKSDGDIPVVRRAKALKSAFSHMTPNIIPGEKIVMQ
                     KTRHYRGSFPMPWVSESFFVAQGEQMREEAKKLASNTADELTKFGSGGGNVTESFGNV
                     VSIAGKFGMRKEEVPVLVKMAKEWVGKSVEDLGFHYEKMMPDYDLKENLMSTLICMFD
                     SGYTLPQGREVINYFYPLNYGLDGIIEMAKECKKAVAGNASGDGLIGMDRLYFYEAVI
                     QVIEGLQTWILNYAKHAKYLESIETDLEAKKEYSDLVEILEHIAHKQPRTFREALQLT
                     YTIHIASVNEDAISGMSIGRFGQILYPWYEQDIEKGLITKEEVIELLELYRIKITCID
                     CFASAGVNGGVLSGNTFNTLSIGGLKEDGSTGANELEELLLEASMRCRTPQPSLTMLY
                     DEKLPEDFLMKAAECTKLGSGYPAWVNNSNGTTFMMKQFADEGMTVEEARAFALGGCL
                     ETSPGCWKQLTLNGKTYSIAGGAGQSAGSGVHFIANPKILELVLMNGKDHRMNIQVFE
                     PHNKPLDTYEEVIEVFKDYYKQAINVLERANNIELDIWRKFDTSIINSLLKPDCLDKG
                     QHIGNMGYRYNATLNVETCGTVTMVNSFAALKKLVYDDKAFTIEEMKDAILNNFGFKD
                     ALEVGNYSMADQVKVDKTGKYDAIYKACLDAPKYGNNDLYADNILKNYEVWLSKVCEE
                     AQSLYAKKMYPCQISVSTHGPQGAATLATADGRLSGTTYSDGSVSAYAGTDKNGVYAL
                     FESATIWDQAVVQNSQMNLKLHPTTIKGQQGTKKLLDLTRSYLRKGGFHIQYNVVDSE
                     TLKDAQKNPDNYRQLMVRVAGFTQYWCELGKPIQDEVIARTEYEGV"
     gene            50960..51217
                     /gene="hpdC"
                     /locus_tag="KR294_000880"
     CDS             50960..51217
                     /gene="hpdC"
                     /locus_tag="KR294_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate decarboxylase small
                     subunit"
                     /protein_id="HBH0238987.1"
                     /translation="MRKHSDCMNFCAVDATKGICRLSKQMINLDDAACPEIKVMPKCK
                     NCKNFVEANDEGIGKCVGLEKEDWVYSTLNAITCEGHVFNE"
     gene            51210..52160
                     /gene="hpdA"
                     /locus_tag="KR294_000881"
     CDS             51210..52160
                     /gene="hpdA"
                     /locus_tag="KR294_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate decarboxylase activase"
                     /protein_id="HBH0238988.1"
                     /translation="MSSQKQLEGMIFDVQSFSVHDGPGCRTTVFLNGCPLSCKWCANP
                     ESWTVRPHMMFSELSCQYENGCTVCHGKCKNGALSFNLDNKPVIDWNICKDCESFECV
                     NSCYYNAFKLCAKPYTVDELVQVIKRDSNNWRSNGGVTFSGGEPLLQHEFLHEVLLKC
                     HEVNIHTAIETSACVSNEVFNKIFNDIDFAFIDIKHMDREKHKEQTGVYNDLILENIS
                     NLANSDWNGRLVLRVPVISGFNDSDENISDIISFMHKNNLVEINLLPFHRLGESKWIQ
                     LGKEYEYSDKGDVDEGHLGELQDIFLDNGIACYVGHETAF"
     gene            52475..53437
                     /locus_tag="KR294_000882"
                     /pseudo
     CDS             52475..53437
                     /locus_tag="KR294_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112760.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
     gene            complement(53536..>54233)
                     /locus_tag="KR294_000883"
     CDS             complement(53536..>54233)
                     /locus_tag="KR294_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBH0238989.1"
                     /translation="YSLLIVLKLLNLINNNEFIIINLILTFISSLSIIIYSSNKKNLY
                     PIKNIKLGSLLIIYFMISVIVPTSFILILQGSQPNYSGIIKFIFTPITSLTTIYIFFS
                     EEYAWRGFLQNIFFNKFGKKLGVIILGICWSLWHLPLIFTLYTPETPILGLILRSIHI
                     VGISIFLGYLYIKTKNIWFCAIIHILNNSAFLITNSKESTITYHDILIVSMVVLIFYV
                     PFLFTKEYKNNLE"
BASE COUNT        21851 a         5780 c        10283 g        16319 t
ORIGIN      
        1 tgatattttt aatgtgttta gagattattt aacaatctcc aaatataaaa ctagaattat
       61 ttacataaaa gttaaatagt ttgtatagag ttagatttat atagtataat acttagtgta
      121 aataattaag aagttatcaa acaggaggat aaaactgtgt tagatataaa ttctttttta
      181 aatggatttt ttaatataat attaagaatg agtatatatg atttaattga catatctata
      241 gtagcgtata ttttttacaa aatatttatg tttataaaag atacaagagc agaacaagtg
      301 tttaaaggta taatatttct tttattagca actcaactta gtaacacctt taaattgcat
      361 accgtttatt ggatatctct taaagcttta gattatggag ttatagctgc tcttataatt
      421 tttcaaccag aatttagagc aggacttgaa catataggaa gagcaaagtt taatttattt
      481 ggaaagaatg taaatacttc tgaagaaact ctcaatagaa atatagaaga aattgtagaa
      541 gctttatatt cactttctag acaaaaaata ggagctctta tcataatgga gagagaaact
      601 agaataagtg atataataaa tacaggaact attattgatg ctgaaatttc taggcaacta
      661 ttaataaata tatttatacc aaatacacca ttacacgatg gagctgttgt aattagagat
      721 tctaaggtaa aagcagctgc atgttttttg ccattgacag aaagtaagga tttaagtaaa
      781 gatttgggca ctagacatag agcaggaata ggggtaagtg aggtgtctga ctgtataact
      841 ttgattgtat cagaggaaac aggtggcgta tcaattgcta aagcaggtaa gttatataga
      901 gatatttcta gagaaagaat gatgaatata ttacgtagta atttaaaaac aaatacagaa
      961 acaagaagtt ttttcaaagg tggtatattt aaatgataaa tagactaaaa aataatacca
     1021 aaataaaaat aatatcattt ttaagtgcaa ttgcattatg gatgtatgtt atggctgtag
     1081 ttgaccctga agaaactaaa gggtttgaag atatacctgt atctataagt aatatgagtg
     1141 atttaaagga taaaaatctt gttatatatc cagacgaaaa attaacagca gatgtatata
     1201 taaaaggtag tttatcaaag gtacaaagtg ttaaaaaaga agatatacat gtatatggaa
     1261 ccattgaaga cccaatacaa ggacagaagg aagtatattt aaaagcaaat attcctcaag
     1321 gtgttactct agaatttaag catgatgttt tagtagtaaa tcttgaaaaa aacataaaag
     1381 aaaaaagaga tataaaggta gaagtaagtg gaaattcaaa aagaaatata aataaaattg
     1441 aacttagtaa ggaatttgtc gatgtatcag gtccaagaac tctagttaaa gaagtcaaaa
     1501 gtgtaagagc taatctagat gttggtaatg agacagatga tttttctaaa aaattgcaat
     1561 taataccatt aaatagtgat ggaactaagg ttgaaggagt aacattaagt tcatcctttg
     1621 tgactgcaaa gatagagcta ttaaaggaaa aaattgtccc aataagagta agtctaaatg
     1681 ataataaaga taatgatgta ctgaaaaact ataaattaag taaggaacaa gttacaataa
     1741 aaggaaagaa agaagatata gacaaaataa gttatattaa gacaaaacct attgacttag
     1801 ctgatttggc taatggtgaa gaaaaagaag ttagcttaga aattccagag ggtataactc
     1861 ttgaggatag ctctataaca attaaattaa atgatacaaa acaattgagt gcagaatttt
     1921 tatataatgc gggagatatt gaattaagaa atatcccaac aaatatggat aatccaaatg
     1981 taatttctga tgtagatata aaagttgttg tagagtcaac ggaggatttg agtaagttaa
     2041 ataaaaaaga tatttcatta tatattgatt tatcacaagg tcctgaggaa gatagtaaat
     2101 ataaaataaa atatgaaaca acatatcaat ttaaaaaaat aaatatagaa cctaatattg
     2161 ttgaagtgga atgaacaaat atttcgaata tttagttgtt acaagatgcg acaaaaaaac
     2221 ctataaaatt aagtttgtta attttatgtt tttgttgcat cttgtttatt ttagttatat
     2281 tataaaataa ggacaatgag atatttgtta aatctaaaaa gcgctagata tatgaaaaaa
     2341 gactgataaa tagatttaaa taaatatttt gaattaaata tttcaattat ctctaggaaa
     2401 acgttgctga acgagttata atttaattga gatataaaaa gttctatttc aaaaaattca
     2461 agatgaggtg gaaatgcatg agaagttttg aagaagtaat taagtttgca aaagaaagag
     2521 gacctaaaac tatatcagta gcatgttgcc aagataaaga agttttaatg gcagttgaaa
     2581 tggctagaaa agaaaaaata gcaaatgcca ttttagtagg agatatagaa aagactaaag
     2641 aaattgcaaa aagcatagac atggatatcg aaaattatga actgatagat ataaaagatt
     2701 tagcagaagc atctctaaaa tctgttgaat tagtttcaca aggaaaagcc gacatggtaa
     2761 tgaaaggctt agtagacaca tcaataatac taaaagcagt tttaaataaa gaagtaggtc
     2821 ttagaactgg aaatgtatta agtcacgtag cagtatttga tgtagaggga tatgatagat
     2881 tatttttcgt aactgacgca gctatgaact tagctcctga tacaaatact aaaaagcaaa
     2941 tcatagaaaa tgcttgcaca gtagcacatt cattagatat aagtgaacca aaagttgctg
     3001 caatatgcgc aaaagaaaaa gtaaatccaa aaatgaaaga tacagttgaa gctaaagaac
     3061 tagaagaaat gtatgaaaga ggagaaatca aaggttgtat ggttggtgga ccttttgcaa
     3121 ttgataatgc agtatcttta gaagcagcta aacataaagg tataaatcat cctgtagcag
     3181 gaagagctga tatattatta gccccagata ttgaaggtgg taacatatta tataaagctt
     3241 tggtattctt ctcaaaatca aaaaatgcag gagttatagt tggggctaaa gcaccaataa
     3301 tattaacttc tagagcagac agtgaagaaa ctaaactaaa ctcaatagct ttaggcgttt
     3361 taatggcagc aaaggcataa ttttaagggg gaaataggca aatgagcaaa atatttaaaa
     3421 tcttaacaat aaatcctggt tcgacatcaa ctaaaatagc tgtatttgat aatgaggatt
     3481 tagtatttga aaaaacttta agacattctt cagaagaaat aggaaaatat gagaaggtgt
     3541 ctgaccaatt tgaatttcgt aaacaagtaa tagaagaagc tctaaaagaa ggtggagtaa
     3601 aaacatctga attagatgct gtagtaggta gaggaggact tcttaaacct ataaaaggtg
     3661 gtacttattc agtaagtgct gctatgattg aagatttaaa agtgggagtt ttaggagaac
     3721 acgcttcaaa cctaggtgga ataatagcaa aacaaatagg tgaagaagta aatgttcctt
     3781 catacatagt agaccctgtt gttgtagatg aattagaaga tgttgctaga atttctggta
     3841 tgcctgaaat aagtagagca agtgtagtac atgctttaaa tcaaaaggca atagcaagaa
     3901 gatatgctag agaaataaac aagaaatatg aagatataaa tcttatagtt gcacacatgg
     3961 gtggaggagt ttctgttgga gctcataaaa atggtaaaat agtagatgtt gcaaacgcat
     4021 tagatggaga aggacctttc tctccagaaa gaagtggtgg actaccagta ggtgcattag
     4081 taaaaatgtg ctttagtgga aaatatactc aagatgaaat taaaaagaaa ataaaaggta
     4141 atggcggatt agttgcatac ttaaacacta atgatgctag agaagttgaa gaaagaattg
     4201 aagctggtga tgaaaaagct aaattagtat atgaagctat ggcatatcaa atctctaaag
     4261 aaataggagc tagtgctgca gttcttaagg gagatgtaaa agcaatatta ttaactggtg
     4321 gaatcgcata ttcaaaaatg tttacagaaa tgattgcaga tagagttaaa tttatagcag
     4381 atgtaaaagt ttatccaggt gaagatgaaa tgattgcatt agctcaaggt ggacttagag
     4441 ttttaactgg tgaagaagag gctcaagttt atgataacta atgataaaag aataagaatc
     4501 ataactggtc actatggaag tggtaaaagt gaatttgcga tgaactatgt tgttaagtta
     4561 agagatatgg tttctggcaa agttgctata gccgatttag atgtggtaaa tgtatacttt
     4621 agaactagag aaaagaaaga gttaatgaaa tccttaggta tacaaccaat agatagctca
     4681 attaatgctc caacattaga tttaccagca gtatcagcag aggtaatgtc tcctatggta
     4741 gaccattcat acaattctgt tatagattta ggtggagata atgtaggtgc tagggttata
     4801 ggaagattta gtcatttgtt aaaagaaggc gattatgata tgctttttgt aataaatgca
     4861 aatagggaga aaactcaaac ttctgaagaa gttatccaat atataaaaga aatagaaaaa
     4921 tcttctaaat taaaggtaac aggtctaatt aataatactc atcttattag gtttactact
     4981 attgatgatg ttttaagagg tcagaaagtt gcaaaagaag tttctgaaaa atgtaatata
     5041 ccgataagat atgttgcatg tttagaaaat cttgttgaac agttaccaaa agatttagaa
     5101 ggagaaattt ttcctataaa attatatatg agagaagact ggatgtagtt tgagctcaaa
     5161 tatatagaaa gtttaaggag gcttaggtaa atggctaaag gaaaagtatc ttttaatcaa
     5221 gaacgttgta aaggttgtgg attgtgtgtt gaagcatgtc cagtaaaaat catacaatta
     5281 gactcaaatg taataaacaa aaaagggtat aacccagcaa ctgtttttga aatggaaaaa
     5341 tgcataggat gtgcaagttg tgcaactatg tgtccagatg tagttataac agtagaaaga
     5401 gattaattta attaatattt aagggggaat tttaatggct aagatactta tgaaaggtaa
     5461 cgaagcattt ggaaaagcag ctatagaagc tggttgcaaa tatttcttcg gttacccaat
     5521 aactccacaa agtgaattac cagaatattt atcaagagag ttacctaaaa taggtggagc
     5581 gttcgttcaa gctgaatcag aagtttctgc gataaacatg gtttatggtg gagcaggtgc
     5641 aggagcaaga gttatgactt cttcatcttc accaggagtt gctttaaagc aagaaggtat
     5701 aacatatgca gtaggagcag aagttccttg tgttgtactt aatgtaatga gaggtggtcc
     5761 aggacttgga agtatacaac cttcacaagc tgactacttt atgtctacaa gaggtggagg
     5821 aaatggagac tacagaactc cagtattcgc accagctaca gttcaagaag ctgttgatat
     5881 gataatggaa gcttttgacg ttgcagatta ttacagatca ccagttatgg tagttgcaga
     5941 tggtatgata ggtcaaatga tggagccagt tgaatttaga gctcctgaga agaaaagaga
     6001 attgcctcct aaagattggg caactgttgg aactaaagga aaaagaaaac ctaatgtaat
     6061 aaactctcta tacttagagc cagaagtact agaagaccat tgttggcatt tacaagaaaa
     6121 atttgatgca atggaaaaga atgaagtaca atacgaaatg tacaaaacag aagatgctga
     6181 atttgtattt gcagcttatg gaactacttc aagagtagta aaaagcgcaa ttgatatatt
     6241 aagagaagaa ggaataaaag caggtcttat aagacctaaa gtattatggc cattcccatt
     6301 cgaagcattc aaccaaattc ctaatgctag aaacatattg actgttgaaa tgagtatggg
     6361 acaaatggtg gaagatgtta aaatggcagt agaaggtaaa ttaccagttt acttccatgg
     6421 aagaccagga ggaatgactc caacaccagc agaaatagtt gaaaaagcta aaaaaattat
     6481 tgccggagaa ttggttgcag gaggtgctag ataatggctg ttgtatttaa gaaaactgaa
     6541 ggattacaag atactcaaac tcactactgt ccaggatgta cacatggtat aatccataga
     6601 ttagttggtg aagtattaga agaactagga gtattaggtg atgctgtagg tgttgttcca
     6661 gttggatgtt cagttttagg atataaatat tttaactgtg acactcaaga agctgctcat
     6721 ggtagagcgc cagctgctgc tacaggaata aaaagagttc atcctgaaaa tacagtattc
     6781 acttatcaag gtgatggaga cttagcttca attggtactg ctgaaatagt tcatgcagct
     6841 gctagaggag aaaaaataac tactatattt gtaaacaata caacttatgg tatgactggt
     6901 ggacaaatgg ctccaactac attagttgga caaagagcta ctactgctca atcaggaaga
     6961 aatgctgaaa ctcaaggtta tccaataaga gtaagtgaaa tgttagctac attaacagga
     7021 gctgtatttg tagaaagagt agcagttgat actccagctc atgttagaca agctaaaaaa
     7081 gctataaaga aagcattcca agttcaacaa gcaggattag gatttggaat agtagaagta
     7141 ttatctactt gtcctacaaa ctggggacta gctccaaacg atgctttaca atggttaaga
     7201 gacaacatga taccatacta tccattagga aatttcaaaa atgttgaagt tgaggaggtg
     7261 aagtaaatgt ctacagctag agtaatatgt gcaggcttcg gaggccaagg tgttatgtct
     7321 atgggacaat tacttactta tgcaggaatg ctagaaggaa aagaagtttc ttggttacca
     7381 tcttatggac cagaaatgcg tggaggtaca gcaaactgtg cagtaactgt atctaatgag
     7441 ccagttggtt ctccacttat aacagatgat gcaactgcag ctatattatt aaatatacca
     7501 gcatttgaaa aattcaaaga tgatgttatt cctggtggaa aaataatagt aaatagttct
     7561 ttaataaaag aaaaagttga tagaacagat gtagatgttt attatatacc agcaaatgaa
     7621 ttagcagctg aattaggaaa tgataaagtt gctaacatga taatgttagg tgcttactta
     7681 aaagtatctg atactgtaga tatagaatct gtactagaag cattcaaaaa agttttcgga
     7741 cctagaaaag aaaaattcgt tccattaaac agagaagctt tacaaaaagg tatggatgct
     7801 acatgttcta aagcaactaa ctaataaaga aaaagatgtc aaaaaaaaga caatagaatt
     7861 atttctattg tcttttttgc tgataagtat taaaatattt ttatgactga aattaagcct
     7921 ataatgatat tttatgaact ataaaaatat aatacaaatt acaagctttt caattatgaa
     7981 aggagaatct ttagtgagaa agtattttgg aacagatgga gttagaggag tagcaaatac
     8041 agaactaaca tgtgatttag catataaact tggtagagct ggtggatttg tcttagctca
     8101 aggagaccac agagtaaaag tagtagtagg taaggatact agaatatcag gtgatatgtt
     8161 ggaagcatct ttaatagcag gacttatgtc tgttggatgt gatgttatta ctgttggaat
     8221 aataccaaca cctgcagtgg catatttaac tagaaaatat ggtgctgatt gtggtgtggt
     8281 tatatctgca tctcacaatc ctgttgaata taatggaatc aaattcttta ataagaatgg
     8341 atataaatta gatgatgaaa ttgaattgaa aatagaagaa tatatagacg atatagacaa
     8401 aattgattgt cttccaattg gtgaaaatgt aggaagaaaa ttacatgaac attgtgcaca
     8461 aagagactat gtagactacc taaaatcaat aataagcact gactttaagg gattaaaagt
     8521 agttttggac tgtgctaatg gtgcgtcata taaagtggca ccaatagtgt ttgatgaact
     8581 aggagcaagt gtaatttcaa taaatagttc accagatgga aataatataa actataaatg
     8641 tggctctaca catccagaac aacttcaaag ggctgttttg gaacataatg ctgacttagg
     8701 tcttgcatat gatggagatg ctgatagatt aattgcagta aatgaaaagg gtcaaattgt
     8761 tgatggagac catataatga tattgagtgc cttaaattta aagaaaaata ataaattggc
     8821 acaagatact ttggtagtta cagttatgag taatataggg ttgacaatag ctgctaagga
     8881 aaatggaata aatttatcta ctacagcagt tggagacaga tatgttttag aagatatggt
     8941 taaaaatgga tataatcttg gtggagagca atctggacat atgatatttt tagattacaa
     9001 cactactgga gatggagtgc ttagttctct aatacttgca aatataatct tgcaagaaaa
     9061 gaaaccttta tcagaaattg catcaataat gagccaatac ccacaagtat tagtaaatgc
     9121 aacaataaaa aatgaaaata agaacaaata tatggaatat ccagaaataa aaactgagat
     9181 agaaagaata gaatctattt tagacggaaa tggtagagtt ttgataagac catcaggaac
     9241 tgagccatta gttagagtta tgttagaggg taaagaggaa ggtcaaataa aagaattagc
     9301 aacaaactta gctaatctta tacaagaaaa attatcgtaa tttaaagggt attctcagat
     9361 ataaatactg aggacacctt tctaagcgcc agaacttagt tatagacata attattgagt
     9421 aatataggaa ctaagttgac gaggtcagag ttaatcgaat tgtcggcgga tgctctgcgg
     9481 tgtgtttacc atcgaaagac ttctttaaat aataggagca atcctatgga caaagggaag
     9541 ccaaagtaaa cttatatgac ctaactctta aaatatataa ataatatttt taggaggaca
     9601 caaataatgt gtggaatagt tggatattta ggaagtagaa aggcagcaga agttatagta
     9661 gaagggcttt ctaagctaga gtacagaggt tatgactcag caggagtagc agttaatagt
     9721 tctaatgaaa aagaacttaa tattagaaag tttaaaggta gactttctgt acttgcagaa
     9781 gacttagaaa agaatcctat tgatggaaat ttaggtatag ggcatacgag atgggcaact
     9841 catggagaac catctgatgt aaactcacat cctcatttta atcaagccaa aacaatagca
     9901 gttgttcata atgggataat agaaaactat atggaaataa aagaagaatt aatttctgaa
     9961 ggtgttaagt ttgaatctca aacagataca gaggtaatag cacatttagt agataaatac
    10021 tatgagggta atttattaga tgctgtatac aaaactatat caaaattaag aggagcttat
    10081 gcattaggtg ttatatgtaa agaacatgga aatgaattag ttgcagtaag aaaagatagt
    10141 cctcttgtag ttggtgttgg tgaaggtgaa aactttatag catcagatat acctgcatta
    10201 ttaaaatata ctagagatgt ttatttctta gaaaatggag aagtagttca tctaaaagac
    10261 gaaaatgtaa cagtttatga ctctaataga aatcttgttg aaaaagaagt atttcatgta
    10321 acttgggatg tagaagctgc gtctaaaggt ggatatgact actttatgtc aaaagaaatt
    10381 catgagcaac caacaggagt aagagaaact ttagaaagaa gacttgatga taatggaaat
    10441 ataattctag acagtataaa tatttctaaa gaagacttag aaaaaataaa taaagtttat
    10501 atagtggctt gtggaacagc atataatgct ggattacttg gtaagtatgc catagaaaaa
    10561 tttgtaaata taccagtaat aactgatata gcatcagaat ttagatatag cgacccattt
    10621 gtagatgaaa attcattagt aatattagtt agtcaatctg gtgagacagc agatactcta
    10681 gcagtattaa gagattcaaa ggctaaagga gcaagaatac tttcaataac taacgttgta
    10741 ggttcatcta tagcaagaga atcagatgat gtattctata cttgggcagg acctgaagta
    10801 gcagttgcat caactaaggc atatactact caaataactt ctttatacat gatagcttta
    10861 gactttgcta tcaaaaaagg aacaataact agagaatttt atgatagtat gatttctaag
    10921 atgaaagaaa taccatcaaa aatacaagaa atactagaca atgaagaata tataaaagaa
    10981 gttgctaaaa cagttgttag ttctgaacat gcattctatt taggaagagg tatagactat
    11041 agcttagcaa tggaaggttc attgaaatta aaagagattt catatataca tgcagaagct
    11101 tttgcagcag gagagctaaa gcatggaaca atagctttaa tagaaaaagg aactcctgta
    11161 attgccatag ctactcaaga aaagttattt gaaaaaatgg tttctaatat ggaagaagta
    11221 agagcaagag gagcttatgt agtagcaata gctcaaagcc ataataagga tgttgagaaa
    11281 gctgctgata aaataatcta tataccaaat tcagatgata ttttatcacc aatattagca
    11341 gttgtaccaa tgcaattact tgcttatcat gtctctgtac taagaggatg cgatgtagat
    11401 aagccaagaa atctagctaa atcagtaaca gttgaataaa aacagattaa aaattaaata
    11461 gataatattt attgaaaaga actcatcctg ttatttgtat tttataggat gagtttttta
    11521 aataaatatt aaatttgttt tgtttttgct ataataaatt ttataaaaag attgatatta
    11581 aatcatctgt aaaatgataa atatatagac cataccaggt atagggaacg ataaatatag
    11641 ttcatataaa atatagtgag tacttaataa acatatagtc aatatcagat aaaaaaaata
    11701 atagcttatg agaaaaatta aaatacaagg tattagtaac cttgtgataa gataaagtga
    11761 gtagtttaaa ataagaatat aaggaactat ttataaaaga atataatgaa gctaataaag
    11821 tataagaaaa ttactttatt ttagtaaaat aatttcaaat aaaaattttt taaattggga
    11881 gtataaatta tgacaaatga ttttaaaaaa gaaaagaaag aagattattt tgttaatctt
    11941 aaggcaatat ctactgaagt tttacaagaa aaagtgcaag ataacgcttg ggttatagtt
    12001 gatactcgct taaatgatgc ttataatggc tggaagttag atggagtaaa aagaggtgga
    12061 catataaaag gagcagtaga tttttctgct aattggttaa gtgtatactc agatagaaaa
    12121 gatgaagtgc tagaacaagc attgaaaact aaaagaattg atttagataa aaatatagta
    12181 ttatatgatg caaatggaaa agatgctttg gttgtagcag attatttatc taaaaaagga
    12241 tataaatatc tatataaata tgatattaaa caatgggcag acaacgaaaa tcttccaatg
    12301 gaaagatata aaaattatca aatgatagtt cctgctttta taataaaaga tatattagat
    12361 ggaaaaattc ctgagacatt tgaagattca aagaatataa aaatgattga agcgagttgg
    12421 ggagaagaat cgtatacaaa agggcatata cctacaagtg ttcatgtaaa taccgatatt
    12481 atagaacctc ctccaacatg gatgcttgat aatgatgata acttaattaa gtttgcttta
    12541 gactatggat taacaaagga tgatactgta atagtttcaa gtagtacacc tatggcatct
    12601 tatagactag ctgttatatt gagatatata ggagtaaaag atgtaagagt tttgaatggt
    12661 ggaacaaact catggttatc agcaggatat gaattagaat ttactagtaa tccaaaacat
    12721 tcatgtacta attttggagc agatatacca gttaactcac aattagttgt tactacctct
    12781 gaattaagac aaaaactaaa agaaaaaaat aagtttatac tagtagataa ccgtacttgg
    12841 gatgaacata taggaaaagt atctggatat acatattatg ataaaaaagg gcgtatacca
    12901 ggagctttat atggacattc aggtagtgat agtgtttcac tagaagaata tcgtaatatt
    12961 gataatacaa tgagaaataa atatgagatt ttagaaatgt gggacaagga aaatatagat
    13021 gtgaatagac agcttatatt tatgtgtgga agtggatggc gtgctgctga agtattaaca
    13081 tacgcaaatg tcataggagt ggaaaatacc tccctttata gtgatggatg gatgggctgg
    13141 agtcttgata attcaaattt aattgaagtg ggagaacaca aataaagttt ttgaaagtac
    13201 gatagagttg tttaaaacaa aggtgttttt gatttattgg gaagagtgtg taaattgtgt
    13261 tttgggaagt gtacttaggt atgttcattt ggagctatgg aaattgataa aaaagtatta
    13321 tctgtttatt ttgctggtaa aatgtgaata gattatagat tatagattat agattataga
    13381 tttaagtata gactaagtaa tttatattac agaagagaat atataagaac tagtgcaaga
    13441 tgtatttgat acatataaaa aattggcaaa tccagaataa ggatagagaa aattgagatt
    13501 gaagagtttg aaagagactt attagatgaa aaatacaaag atgtataaaa atacatattg
    13561 agaaagtata tctctcttaa atttgttaat aattctatta tacagaaaaa catatttaag
    13621 ggggattttt tactatgaaa agagtaaaat tagctataag cttttttata ttaatgatta
    13681 tagggatgac aatatcttat gcagatacaa gtataaatac taaatacaat agattaagta
    13741 aagctcttga aatttcagaa gcaaatttta aattttataa tgttaaaatt aattctgtta
    13801 taaatcataa tttatcaaat aaagaatttc ataatatttt tatagaaata attaacaatc
    13861 taaagttgga taaaaaagga ataaattgga atcaaaaagg gtctggcgat aaaatacaat
    13921 tatgtgctac tataaaaggt agcgataaag aaatttctat aaaaggaata aataaaaata
    13981 acaaagaaag ttacatagta gttgacatat tggataacaa agtatataaa cataaagagg
    14041 ttatttatag taacgtagaa aatgtgttaa ataaatattc atctcaagta gatgtgtctg
    14101 cttgtattgt tggagaatac acaaaaaggt tacaaaacaa caaatatgat gatattttac
    14161 aaaaaatatt atataatatg agtgctaagc aaatagatga agtgaaagac gtaaactttt
    14221 tatctataac agcatatagt aaagtattaa atgattatga attagaatat ttaggggaaa
    14281 aaattaattt aaatatagga attaaatata atgaggacga cggaagaaca ctcatatata
    14341 ttgccacacc aattataaaa ttagattatt aattatgagg agatcaaaaa atatggctaa
    14401 gataatagta aaaaagagta atccacttaa aggtagtgtt aaaatagatg gtgcaaaaaa
    14461 tgcagtttta ccaataatag cagcgacttt attagcaaac gggaaatcaa cattaaatgg
    14521 agtaccaaat ttaagagatg ttcatgttat atcagattta ttaagacatg taggggcaga
    14581 agttgaatat aaagaaaata cacttactgt tgatgcaagt aatataaaaa cttgtgaagc
    14641 tccatatgag cttgtaagaa agatgagagc ttcttttttg gttatggggc cattgcttgc
    14701 tagatttaat agtacgaaaa tttctatgcc aggaggatgc gctataggaa caagacctat
    14761 agatttacat ttaaaaggat ttaaagcctt aggtgcaaag atagaaatgg accatggttt
    14821 tgttgaagca gcaacagaaa aattagtagg aaataaatta tatttagatt tcccatctgt
    14881 tggagcaact gaaaacataa tgatggcagc ttctttagca gaagggacta caataataga
    14941 gaatgcagca gaagagccag aaatagtaga tttagcaaac ttcttgaacg aaatgggagc
    15001 agatgttaaa ggtgcaggta ctaatactat aaaaataaaa ggtgttaaag agttaaaagg
    15061 agcagaacat aatgtaattc cagacagaat agaagcagca acttatatgg ttgcagcagc
    15121 tatgacaaaa ggtgatataa ctgttgaaaa tgttttaatg gagcatttaa aaccagttgt
    15181 agctaaatta agagaagctg gttgtgaaat aacagaaatg gacaattctg taagagttgt
    15241 aggtccaaaa gtattaaaac caatagatat aaaaacttta ccacatccag gatttcctac
    15301 agatgttcaa gcacaattta tggctatgct tactgtagct aatggaactg gtgtagttat
    15361 agaaactgtt tttgaaaaca gatttatgca tgttgctgaa tttaatagaa tgggtgctaa
    15421 tataaaaata gatggaagaa gtgcggttgt taatggtgta gatgagctac atggtgcagc
    15481 agtaaacgct actgatttaa gagcaggggc agcccttatt ttatgcggtc ttatagcaga
    15541 aggagaaact caaataggag aaatatacca tatccaaaga ggctatgttg atatagataa
    15601 gaagataaca gcattaggtg gtcaaatcga aatagtagaa gattaataat tggtttatag
    15661 aagaaagtta taaattaata gggttgttca tatacttaaa tacaaggttt taaaagctaa
    15721 ggaggagagt atatgaagaa cccattggtt gttttgttag gatttgtgac ttgctctgtg
    15781 ttagttccat cacttataac tttagtttct tataaaaatg tagaattaac tgaaaaagca
    15841 gagagcccag tatctataaa caaaactatt aaaaaaagtg atattgaaga caaaggtaat
    15901 aaagaagaaa aaaatacagt gaactatgaa actgtaaata aaaaagcacc aattatcaat
    15961 gtatataatc atataacagg gaaaaccgaa aagatggaca tggagaacta tttatgtgga
    16021 gtactagctg gtgagatgtc ttcagagttt gatatagaag ccttaaaagc tcaatctgta
    16081 gcagctagaa catatgtagt atataaacag gaacatggta aatctagtaa acataaaaat
    16141 gcagtagtat gtactgatta taaacattgt caagaatata agagttatga tactcttaaa
    16201 aaattaaatg gtgaagaatg gattaagaat aaatattcca aaatccaaga agcagttaga
    16261 ggaactaaag gtcaaataat aacttataac gataaggcga tacttcctct ttatttttct
    16321 acatcttcag gaaaaacaga aaatagtgaa gaagtatttt ctgcaaaata tccttattta
    16381 aagtctgtgg aaagtcctta tgataagtat tcccctaaat ttgcgtcaac acttaaaata
    16441 agcaacacag attttgttaa aagtcttaga agggcatata gcactattgt gatagatgtg
    16501 aataatttaa gtaaacaagt ttcaataact aaaagaagtg atgccggaac tgtagaaaaa
    16561 ataaaattag gaaataaaga attgactgga aaagacatta gaactgtttt taaattgaac
    16621 tctgcaaact ttgacataaa atttggagaa ggatacatag atttcgtggt aaaaggatat
    16681 ggtcatggtg ttggtatgag ccagtgggga gcagaaggaa tggcagaaga gggctataaa
    16741 tattatgata tattatcaca ttactataca gatacaaaaa taaaagatat atactaataa
    16801 ttgtataaaa tgccaaaaac acgtcaataa tccaaatgta gaaatatatt tggaggtgca
    16861 aaatgaagaa aaagctgtta gaaaaagatg gtttttattt atctttgttt gtatgtgttt
    16921 gtttattagc agtaggtgga gtttggttta caaataataa tgtagataaa ttggcttcta
    16981 ataaaggaat tatggaaaat gctaataaag atagtgaaga ggaaatacat ttaattgaaa
    17041 aagacaagaa agatgctatc cctactgcaa cggattcaaa acaaaactta gaaaaagcta
    17101 agtcaaaaga ggaaaataaa tcgagtacaa caaaattaaa ttacattgga gataaagtaa
    17161 taagaggata ttcagaaaaa gaacctagtt attctaaaac acttgatgtt tgggaaactc
    17221 ataaaggtgt agatattagt tgtactaaag gcaaagaagt aaaatctcta ttaaacggaa
    17281 tagtagtaga tgtatttaat gatgaagaat atgggcaatc agtcaaaata aaaagtgaca
    17341 ataacattgt agtagtatat tcaaatctag ataaaaatgt tagtgttaag aaagaacaga
    17401 aggtaacaga aggacaatct ctaggtactg taggtagtac ttctcaaata gaaagtgaag
    17461 aaggtataca tgttcattta gaggcgtata gtggagaaaa atctatagac ccaatgagtc
    17521 taattaagta aaagtataac aagtttaatc atatttggtt aagcttgtta tattttttgg
    17581 tgtttttaca tatatatcat taaagctatt atgtgagggg ggtaatcttt gagatctcat
    17641 atagaggaaa gggccatagt ggtagcaaaa tatatacttg aaaaaaacac tacagtaaga
    17701 caaaccgcca agacatttgg agtaagtaaa agtacaattc ataaggatgt tacagaaaga
    17761 ttgaaggaaa taaatccatc ccttgccaaa gaagttaaaa atgtgctgga caaaaataaa
    17821 tcagagagac atattagagg gggattagca acgaaattaa aatatgagaa ggaacataaa
    17881 aaaatgtagg ttaaaaacct acttttttta tttaattaaa ttataaaaag aaatatatta
    17941 agtaattata aatagcaaaa taataatact ctcaaaagat ttattttctc ttgattaaag
    18001 cgagattttt gtatatgctt tattatagga gtattaaaat aggcttataa tataatctaa
    18061 tattataaat aaaggagttg aaaaaatggc tggagctgat ataggcatag atttaggtac
    18121 tgcaaatgtg cttgtttatg ttagtggtaa gggaatcgtt ttagaagaac cgtctgttgt
    18181 ggcgatagac aacagaacag attctgtttt agctgtggga gaagaagcta aaaagatgat
    18241 agggagaaca ccaggtaata tagtcgctat aagaccttta agagatggtg taatttcaga
    18301 ttatgatgta actgagaaga tgttaaaatc ttttatagat aagatagttg ataaaaaggg
    18361 atttggaaga ttttttatgc caagaattat ggtatgcgta ccaacaggtg tcacagaagt
    18421 ggaaaagaga gcagtagaag atgctacgag acaagctgga gctagagaag tatatataat
    18481 agaagaacca atagcagcag ccataggagc tggtgtagac atatcacagc ctaatggtaa
    18541 tatgattata gatattggtg gaggtactgt agatatagct gtaatatctc taggaggagc
    18601 tgttgtaagt gaatctataa aggttggtgg agatagattt gatgatgcta tagttaaata
    18661 tatgaaaaaa caacacaatc ttcttatagg agaaagaaca gcagagaaaa tcaagtttga
    18721 aataggttct gcatttaaga gagaagaaga aaaatatatg aagataacag gaagaaattt
    18781 aattacagga cttcctagtt ctataactat aaattcaaca gaaatgttgg aagcacttag
    18841 agaatgtgtt gagcaaatag tagttgctac tcatgctgtt ttggaaaaaa cgcctcctga
    18901 gttagcagca gatataggag atgttggtat aataatgact ggaggaggtt cattattata
    18961 tggattagat aaaataatag aacagagaac aggaataact gttacaatag cagatgaacc
    19021 attatcttgt gttgcaaaag gtacaggaat agctttaggt tcaatagacc tacttgaaac
    19081 tggcgggtct ttcaaaagaa aataattagg agagtttaga atgttaaata tagatgaaat
    19141 aaaaaaatta ataccacata gatatccttt tttattagtg gacaagatta cagagctaga
    19201 agttgggaaa agagctgttg gtataaagaa tgtaacagtt aatgaaccat ttttccaagg
    19261 tcactttcca gaatatcctt taatgccagg agtattaata gtagaagctt tagcacaagt
    19321 gtgtggagtg gcaatgatgt ctgtagagga aaacaaagga aaactaggtg tatttgcagg
    19381 tatagataaa gttagaatca agagagaagt aagaccagga gatacattaa ctatggaagt
    19441 tgaaatgaca actcttagaa gaaatatagc caaggcagat gctaaggcat atgttggtga
    19501 agaacttgtc tgtaaagggg aattaatgtt tgccttagta gaaaaataaa aacttgaaat
    19561 ataaaagtaa aaaggtagat aatttggagt atttaatcag atactctaaa atatctacct
    19621 ttttatataa agaattttat catttagttt atatttagat taggtggata ctaataaagc
    19681 caaggctatt gtttcagcta agtctaatat aaagctaaga cgtatattat taaatgaaag
    19741 tttattattt tcatcaattt tatctacaat tcctactata gaataatttc ctatttgagg
    19801 tagttttttg ccaacacctt ttccgggcag gataggtcct tctctaatct gtatattacc
    19861 tatgttactc tgcgacccca agcaagcatc tatagccaag aagttacctt gtatatgtgt
    19921 attttttata gtatctaaag actcatatat atttaaggcg tgaatagggt tatctagtgt
    19981 accgtaaacg gggtatttaa agttactgtt cttaagtatt gttccaacta aagggcctaa
    20041 agtatcacct atagccctgt ctgttcctat gcaaacaaca atcgtatttt cattaattat
    20101 agtttttaga actgaactta gcatctgtat aacatcatca tcgctgtaat ttactttagc
    20161 taaatacaat aggaacaccc ccttcaaaaa aatatatgaa taaaaagcat taaaaagacc
    20221 taactttaaa tttcagatag atagaaaatt ttatttgtct tacaaaaaaa ggaatagaaa
    20281 aaatatgact aaaaatattg acaaaatttt aaaaaaatag taagctagta aagtaaaaca
    20341 aaacttaaat cttgattacc ttatcaagag aggctgaggg ataggccctg tgaagcccag
    20401 caaccaccca aatgggaaaa ggtgctaatt cctacaagac aaaagtcttg aaagatgagg
    20461 tcagttaatt agtatgtaat tacgattatt aacctcttct tataaaggag aggtttttta
    20521 ttttgagtaa atttctaaaa ttaaaaataa ggtaaaacct ataataaaaa ctaagaataa
    20581 ataaggggga ataaaaatgg caagacattt atttacgtca gaatcagtta cagaaggaca
    20641 tcctgataag atatgtgacc aaatatcaga ttcaatatta gatgcattat tagaaaaaga
    20701 cccacaatct agagtagctt gtgaaactac agttactact ggtttagttt tagtagcagg
    20761 agaaataagt acatctgctt atgtagacat tcctaaatta gtaagagaaa cagtaagaga
    20821 aattggatat acaagagcaa aatatggatt tgattgtgat acttgcgcag ttataacttc
    20881 tattgatgaa caatctggag atatagctat gggagttgat gaaggcctag aaagtaagac
    20941 tggagaagag atagaagaag aaatagaaaa agttggagct ggagaccaag gtataatgtt
    21001 tggatttgca tgtaatgaga ctccagaatt aatgcctctt ccaatatctt tggcacacaa
    21061 attatcaaga agacttacag aggttagaaa gactggtcta gttgattatt taagaccaga
    21121 tggaaaaact caagttactg ttgaatatga aggaagtaaa gctgtaagag tacatacagt
    21181 tcttatatca gctcaacatt gtgaaacagt atcaaatgat aaaataagag aagatttaat
    21241 taatcatgtt attaaagaag ttataccagc agaattactt gatgaagata ctaaaattta
    21301 tataaatcca acaggaagat tcgttatagg aggaccacaa ggagatacag gtcttacagg
    21361 aagaaaaata ataatagata cttatggtgg atattctaga catggtggag gagctttctc
    21421 aggaaaagac cctacaaagg ttgatagatc tgctgcttat gcagctagat atgttgcaaa
    21481 aaatattgtt gcggctggtc ttgcagacaa atgtgagata gaacttgcat atgctatagg
    21541 tatagctaga ccattatcta tatttataga tacttttggg acaggcaaag tttcagaaga
    21601 aaaacttgtt gaattagtaa ataaacactt tgatttaaga ccaggagcca taataagaga
    21661 cttagattta agaaagcctc tttataaaaa ggttgctgct tatggtcact ttggtagaac
    21721 tgatatagat ttaccttggg aaagaactga caaggttgag cagttaagaa aagatgcttt
    21781 aggtgaataa tttttaacta aaaagctgtt agaatgtaat tttacgatta ctttctaaca
    21841 gcttttttat tatgagttaa atatttttaa taaatgttaa tttatcatca tataatgaat
    21901 aaacagtatt taatctggtc aatacatttt atataatact atactaaatt tatgcatatt
    21961 atgggatata tgttaaagga tggttaagaa tgtgttaact aatgttaaat aattaaaaat
    22021 atattgaaat atcataataa tgagtctaat ataatcttaa taaacttaca ctttaaaaat
    22081 aattttaatt ggggggagta gtgtatgtca ggcaaagtaa atattaaaac ggttataagt
    22141 tttgctggag cttatgttgc tactgtaata ggttctggat ttgcaactgg tcaagaaata
    22201 ctgcaatttt ttacatttta tggatatgct ggtattatag gtggaataat ctctatggta
    22261 ctattttcat ggtttggagc agaggttata gataagggaa gagaattgaa acttaaggag
    22321 ccaataaaaa tttatcaagt atattgtgga aaatatcttg gaacattttt tgaatggttt
    22381 ggtccattgt ttttatttgg aacattagta ataatgattg caggagcagg agctacatta
    22441 tcagagtact atggattaaa tccatatgta ggtaggattg gtatgacaat cgtttcccta
    22501 ataactgttt cattaggttt gacaaggctt tctaaaatac taggtaatat aggacctata
    22561 ataataatat ttacactttt agtaggagca attagtttat ttagcaatat tgatgcttta
    22621 tcaaatgctg gaaatatggt tgatagttta aatattaaaa ctgctacatc aaatggatat
    22681 ttctcaggag tactttatac ttgttataat gtaataatag taataacatt cttgacagga
    22741 atgggagctt ctgcagtaaa taagaaagat gctgtgtggg gtggtatagt aggtggagta
    22801 gcacttatgg cagcagctat aatgatgaat ttggcattac tttcagacat aggaaatata
    22861 tacacaaaag agataccagc actttactta gctgataaga tatctccaat aataggtatt
    22921 ttattctcag tagtactttt actaggaata tacactacag ctgtaccatt gttatggtca
    22981 gtaactaacc gatttgtaga agatgaccac cctaaattta aaattataac aatagtagta
    23041 agtatattag cttgtatagg aggtctactg ccatttgata agttagtagg tacactatat
    23101 ccatatacag gttacatggg aattttaatt ttactatgta tgctttatag aagaattact
    23161 aaaactgagg ggtacaagga gaataaatct gaaataagct agtactgtaa tatacttatg
    23221 aaatttaatt tatactctaa atatggagta attaaaataa aatagctatt taaatatggt
    23281 acctgtattt catggtacca tattttatgg atgcagattt tttttgtttc tgataaaatg
    23341 tataatagtt ggaaattacg ttaagtataa aaatataaaa cttttctacg attatcatag
    23401 ttttaatata taaaattata ctaacattta aatggagcga ttattagtat ttttaggaga
    23461 taaaaatgga aaaattagaa ggaatgataa gtgaaatagt ctttaaaaac gaagataatg
    23521 gttatacaat agctcatctg gtaaatgaaa atgatgaaat tgtcgttgta ggatgtatgc
    23581 ctactttggc aattggagaa agcatagaag ttgaaggaaa gtgggtaaac cataagattt
    23641 atgggactca atttgaagtg aatagtttta tgccagtaac accatcatcc ttagaaggaa
    23701 tttatgttta cttatcttct ggaatgatac atggtattgg tgaaaaaatg gctaaaagaa
    23761 taattgataa gtttggtgta gatacgttag aggtgataca aaattcacca gaaaaactac
    23821 aagaagtaga aggtataggg agtaaaaaag taaaacaaat agtaaaaagt tatgaagaag
    23881 acagagaatt gagaaatata ataatacagc tatctccttt tggaataaca ccaaattact
    23941 gcctaaaaat atataaaaaa tataaaagca gtgcaataga agttataaat aaaaacccat
    24001 accaacttgc tgaagatata agaggaattg gatttaaagt agctgatagt atagcaaata
    24061 aaattggtat agataaaaat tctaaggata gaatttgtca gggaatctta tacactttaa
    24121 ataaatcttt aagtaatggg catacatatt taccagagca tgttctaata caagattcgg
    24181 aaaaattatt ggagctaaat ggagaaataa taaaagagtg tgtaatgatg ctagtttata
    24241 atcaaaaaat acatgtagag aaagtaaaca atgaaaatct tatatacctt atgccatact
    24301 atttagctga aaatggagta tgtagtcaaa tagtaaaatt atcacagtat gaatttgaag
    24361 acttaaaaat agatatagat aacgagatta atgttttaga agaagataag aaaattaagt
    24421 tagcagaaaa acaaatttta gcagtcaaag aatctgttaa tagtggcgta ttaattataa
    24481 ccggtggtcc aggaactggt aaaacaacta ccattaatgc tatcatagat atatttgaaa
    24541 ataatggtaa aagcgtgact ttggcagctc caacgggaag agcagcaaag agaatgagtg
    24601 aaacttctaa taaagaagca aaaactatac ataggttgct agaaatggga ttttcaacag
    24661 atgatgattt aacttttttt aaggatgaag aagacccaat aaattcagat gtaataattg
    24721 ttgatgaggt atcaatggta gacattatct taatgtacaa tttacttaga gctataaagt
    24781 taggaacaag agtaatttta gttggagata gtgaccaatt accttctgta ggtgctggaa
    24841 atgtacttaa ggatatgatt aattctaata ttataaatgt agttaaatta aatgaaatat
    24901 ttagacaagc gcaagaaagt atgataattg taaatgccca taagataaac aatggagaac
    24961 cactttatct aaatacaaaa ggtaaagatt tcttttttat aagaaaatca actaatgaag
    25021 aaattttaaa tgaaataata ggattggtta atgaaagatt acctaaattt tataaagttg
    25081 ataaattaaa agatatacaa gttttatcct caatgagaaa aggtgaattg ggagttacta
    25141 atctcaatat agagttacag aagtatctta acaaaaaaga aaaatttaaa gttgaagaaa
    25201 gtttttctaa aagattattt agagttggcg ataaggtaat gcaagtaaaa aataattata
    25261 caaaaaaatg ggaaacagaa gaccaaaaag aaagtggaga aggtatctat aatggagata
    25321 taggatatgt ttatcacata gataaagata aaaaaactat ttatatatta tttgaccaga
    25381 ctaaaattgt atcataccta tatgatgaat tagatgaaat tgaccatagt ttttgtacaa
    25441 caatacataa aagccaagga agtgaatttc cagttgtagt attgccaata gcttgggctc
    25501 ctcctatgtt acttagccgt aatttattat atacagcagt aacaagagca aaaaaattag
    25561 ttgtattagt tggagatgtg aaatatcttg aatatatgat aaaaaataat agagttaatc
    25621 aaaggtattc aaatttagga tataagctaa ataaatttaa gcaagaaggg ctgttgatag
    25681 aataaatatg aaaatatgca atgataattt tattaagaat tttaaaaata tgattaataa
    25741 atgtttggat tttatatatc ctgagaatat aagttgcata atttgtgata aatccataaa
    25801 gaaaacaaat acttattcaa tatgtaaaag ttgttttaaa gaaatgaatt ttatacaaga
    25861 tggttgcatg aagtgtggaa aaccaataat acgtcattca attgaaaaag aatttattga
    25921 agaatgtagt tattgtttta ataaagactt ttattttgat aaatcaatat cttgtattga
    25981 atacaatgat gtgacaaaaa agatagtgct agggctgaag tataaccaaa aaacctttat
    26041 ggctaagtat atagctcaaa taatgaaaga aaaattatat ttagaaaaca taaaatttga
    26101 ttatatatta tttgttccac ttcataaaaa aaggctaaat aaaagaggtt ttaatcaggc
    26161 acaaaaaata gcatttaatt taagtaaaat agtaaatatt ccattattgg attgtataag
    26221 tagaaaaaaa tatacaagaa tgctatataa attgaataag aaagaacgaa aagaagaatt
    26281 aaaaaatgta tttgttgtta aagacaatgt taaattaata aataataaaa atatactttt
    26341 aatagatgat atatttacta ctggtctaac aacaaacgaa atttctaaac ttttaaagtt
    26401 atcgggtgct aataaggttt ttgtattgac tctacttaca aaagcaaatg ataattatat
    26461 tatggaataa tcttatatat tgacaatttt aatttaaaat attaaaatga ataagtgata
    26521 tttaggtctg tggttgaaag tccaagccag tcgcaggcaa agggatccac gtaagttaac
    26581 actaaaaatt gggttaatga tcatggtgcg gcttagaagt aagacctacc gataataaaa
    26641 tcgagagaga gtagtagtgc ggcgaaccca agcgaaccct ccagtaggcg agtgtggggt
    26701 caaaaaccag gtcagctaaa tatcgtatta aaagggagct agcatacctt tatgtatagc
    26761 tcttttttat atataataaa tttaggttga gtcataaaga ggtgatatgt ttgaataaaa
    26821 gacaggaaaa cttattaaca acgttgctat taaaagaaga gtttataaat gttaataaga
    26881 ttgccaatga ttttgagtgt tcagaaagga caataagaaa tgattgcaaa tatattgatg
    26941 aatggttatc tactttttgt aatgcttata tcaaaagaaa acctaatatt ggaattaaat
    27001 ttagtggaga tggaacagac aaaatactgg taaatcagaa gttgcgaggt gaagttaaaa
    27061 gagtaaatag tgagcttcat aagcaagttg agatattaaa tttactactt tgtaataata
    27121 aaaaagttac tttaaatgat ttatctaata agttgtacat aaataaaaat attgtcagag
    27181 aagaaataag taaattatca gtggcattaa ataattataa tttaaatgtc tcgactaaaa
    27241 aaggcagtgg tatatatatt ggaggggatg agaaagacat aagaataatg ttagtatcat
    27301 tcttatttaa atacatagat aaatacagat taaacataga tgaaatagag tacttccata
    27361 tagtagatat aataattgta aaaaacataa tgtttactat agaggaggat atggatataa
    27421 gacttacaga tatatcattc aagcaattga tgctattttt acttataaat ataatacgaa
    27481 taaggctagg aaattcttta aaagtatcaa atactaagaa agagcttaag ctaaaaatgc
    27541 tgatattaga tatagaagat gaattgaaat ctaatttatc catagtatta aattatgaag
    27601 aaaaattgtt tatagagtct ttaatattgg gtatgaacaa acaaataaat agtagtaata
    27661 ttaagaaatc tttatatcta aatgaagaat tagcaagtta tacaaaaaaa attataaatt
    27721 tagtatcaga agaatccgga ataaatttta ataatgatat attactttat gaacaattaa
    27781 tatgtcattt gaatgttaca atgcaccaaa tgaaaagcaa tgtttactta gaaaatccac
    27841 ttttagataa cataaaaact aaattttgtt ttttatttac agtaatatca agttcaatag
    27901 aaattgaatt aaaaggaaaa caaataacag aagatgaaat tggttatctt acacttcact
    27961 ttcaaacctc tctagaaaga aaatacagca aaagggaatc aaataaaaag gcaagtattg
    28021 tatgtccatt tagttttgga gtaagcatgc tattaaaagt aaagatagaa aagagatttg
    28081 ataacataaa aattattgaa acattaagag aggaagattt aaaaagagat aacttcaata
    28141 agactataga ttttataatt gcatttcaag agtatgaaaa tatccaaaaa ccaattttta
    28201 taacaacacc attatttact gatgaggatg agaataaact taaagagttc acaaacaaaa
    28261 taaaagaaaa agacacttca tataaactta tgaacagatt aatgatgtct gattatttaa
    28321 taagagagtt agaacatgat gatatttatg aagctataac atatttaact aatttattaa
    28381 ttgaaaaaca ttatgcagaa aaagagtatt tacaatctat tataacaaga gaaaagtcat
    28441 atccaaccaa tgttggaaaa ggaatattat tccctcatgg agatatgaaa tatataaaac
    28501 aatctgtttt atgttttgca aggttaaaaa caccaataag aattagaaat ggaaaggata
    28561 taaagattat acttttgtta gcatataaaa aagatgatga tagaaaagta tttagagaat
    28621 tatttaaaga aatatctaat ttaacagagg atgaaaatat gctagatatt ctaagtaaat
    28681 gtgacattga aaaagtaaaa gatattctta tataaaattc atagtgaact atggataagc
    28741 acaaaatttt ccatgtgatg gaaaaagttg tgcatgtttt tttgttttta taagatatta
    28801 tatgtttgta aggtataaat aatctaaaag tagagaagca acttaggagg aaaaaatgga
    28861 agaaatagtt ttaaagatta taattcatgc tggaaatgca aaatctatgc tttatgaagc
    28921 acttgactat gcaaaggaaa acgattttaa aaaagcagat gaattaattg aaaatgcaaa
    28981 tgaagaaatt ttaaaagcac ataaagtaca aactgaactt atacaaaagg aagctggggg
    29041 agataaatca gatatatcta ttttattgat tcactctcaa gaccatttga tgacttgtat
    29101 gagtgagaga aaccttataa aagaaatgat tatgttaaga aaagaaattc aaaaattaaa
    29161 ataaaaaaat taagggggat ttaaaaaatg aaaagaaaag tatatttatt ttgtagcttt
    29221 ggtatgtcaa caagtttact tgcagataaa atgcagaagg tagcagatga acacaattta
    29281 ccaatagaag tagaggcatt tccgatagca gaaattgaca aaatagttga agaaaaaaat
    29341 ccagattgta tattactagg accacaagtt aaatacatgc taaaggaatt aaaaccaaag
    29401 tttgaagctc aaggaaaact tatagatata atcaatgaag ttgattatgg aactatgaat
    29461 ggggaaaaag tattaaaact cgctataaag ctaataaaat ccaaacaagc gtagaattat
    29521 agtaaaaaat aataggaaat gagggtagat agatgaatag attggaaaga atacttatgc
    29581 cattggctga aaaaataggt aaaaataaat tattaattgc aattagagat ggttttttaa
    29641 tatcatcacc attattaata ataggttcat tatttttatt agtagcaaat tttcctataa
    29701 aaggatggaa tgaatttgta ggtcaaattt ttggttcaga ttgggctgta aaattgcaac
    29761 aaccaactgt agcaacattt gaagtaatga ctctacttgc agttttagga attggatatt
    29821 cttatgcaaa gcaaatagat gtagacccaa tagcatcagc agcagttgca atagttgcct
    29881 tttttataat aacaccattt gtaataccat atacaccaga aggaacagaa tcagtctaca
    29941 tggtaacagg tataccacta ggttggatgg gctctaaggg aatgtttgta ggtatgataa
    30001 cagcaataac ctctgtaaaa ttatttgctg cagttgtaaa aaaaggatgg acattgaaaa
    30061 tgccagatgg agttcctcca accgtatcaa aatcatttgc agcattaata ccaagtgcaa
    30121 tagttatggt agttttcttt ttagttaaga tagcttttga agctacacca tatggaagta
    30181 tacatgaatt tatatttaag tttttacaaa tgccattatt aaaattagga aatagtttag
    30241 gtgctatggc aatcgcttat atattcttac atttattctg gttctttgga ataaatggaa
    30301 gtagtgttgt tggggctgtg tataatccaa tattaaaaat tctatcagct gaaaatttag
    30361 ctgcttttca agctggttca aaaataccaa acataataac aggtcaattc caagatatgt
    30421 ttgcgacatt tggtggagca ggtagtacac tatcattagt catagctatg ttattaatat
    30481 gtaaaagtaa acgtataaag tcaatgggaa aactatcaat tttaccagga atatttggta
    30541 taaatgagcc attgatattt ggtctaccaa taatgcttaa cccaatacta ttgataccat
    30601 ttgcaatagt tccaacaata aatataataa tagcttattt ctgtatgtca gcaggattag
    30661 tgcctcttac aaatggagtt cagttaccgt ggacaactcc aattatattc tctggttttt
    30721 taacaacagg atggcaaggt gcagtcttac aagtagtgct tcttatacta ggaatattta
    30781 tgtatatacc atttataaaa atgctagata agcaatactt aagagaagaa aatgcaactg
    30841 ttgaagagga agatgatgat atatcttttg atgatttagt attataggag gaagatgatg
    30901 aagaaaatag ttatgatatt ggatcaaata caagctggag ctggaggaaa agagaaaagt
    30961 aatatacctc ctgctggaaa atcaagccca ttaggaccag gtataatgat ggagcaattt
    31021 ttaaatgaat ctaaggtaat agctacctta ttttgtgggg atgaattttt tgtaaataat
    31081 gaagaagaag taactagtaa gatgatagct atggtaaaaa aattaaaccc tgatgtagta
    31141 atctgtggac caagctttaa ttacgaaaac ttttctaaga tgtcagcaat actgtctaaa
    31201 aatataaatg ataaaacaga tataccagct tttgcagcta tgtcagaaga aaatatagat
    31261 gtgataaacg aatataaaaa tgacatatgt atagttaaga ctccaaaaaa aggtggaatt
    31321 ggtcttaatg attcattaaa taacatatgt aaattggcaa aagcaatagc aaataaagaa
    31381 gatataactt tgatgaaaga agaattttgt tattaataag agtattaatt attagtaagt
    31441 ttaaatatta tactatttat aataagcata cattagtaaa atctatataa tttaaggagg
    31501 ggaattttaa catgtgggga atgatagcga catggagaat ggccctagaa ggaataactg
    31561 aggcatcaga acatttagaa aaaggcatgg aagcaggtga tgctgtagag cttgctgtaa
    31621 gaagagttga agactatcca ttctataaat cggttggata tggtggactt ccaaatgaaa
    31681 attgtgaggt agaacttgac gctgcattta tggatggtaa cacattagat attggagcag
    31741 ttgctggtat aagagattat tctaatcctg tcagcatagc taggaagtta agttatgaga
    31801 aggtaaataa ttttttagtt ggaataggtg ctgaagatta tgctcataaa aatggatttg
    31861 aaagaaaaaa tatgttgact gatagagcga agttacatta taaaaagaga aaaaaagaga
    31921 ctttagacaa aggattaagt ccatatgctg gtcatgatac tgttggtatg atatctttag
    31981 acaaaactgg aaaaatgtgt gcagctacat caacaagtgg attgtttatg aagaaaagag
    32041 gtagaatagg agattctgca ctatctggtt caggattcta tgttgatagt agtataggag
    32101 gagctacagc tactggtttg ggagaagatt taatgaaggg atgtatatct tatgagatag
    32161 ttagacttat gaaagaaggg aagcatccac aagaagcatg tgatattgca gtaaatgaac
    32221 ttgataaaca gcttatcaaa agaaggggaa aagctggtga tttatcatta gttgccatga
    32281 ataataaagg tgaatgggga gtagctacaa atatagctga ttttactttt tcagtagtaa
    32341 ctaaagaaga atctcctact gtatatattt caaatagagt agatggaaag actatacata
    32401 aggttatatc aaatgagtgg atggaagcat atgaggctag aataaaagca ccaatagaag
    32461 taagtgagta aagtagtggt tacataatta aaatagagtt ttataataag gagattttta
    32521 tgaatatcat aagtaataaa atagatgagt taaaagaaga tttattaagt gatattatag
    32581 atattgtaaa aatacctagt gtcaaagggg agtcagaaaa tggcttccct tttggcgaaa
    32641 aagtagggga ggcacttaat aaagcattag aaatatcaga aaaattggga tttaaggtta
    32701 gaaacttgga taattatatt ggttatgcag agcatggaga tagtgatgat tatgtttgtg
    32761 taattggaca tgtagatgtt gtacatgaag gagatggttg gaagcatcag ccttataagg
    32821 gagaagaaac taatggaaga atttatggac gaggagtact agacaataaa ggacctataa
    32881 tgtctgcctt atatggatta tatgctatta aagaattaaa tttaaaatta gataagagag
    32941 ttagaataat atttggtaca aatgaagaaa gtggatttga agatatacca tattatttag
    33001 aaaaagaaaa agcacctatt atgggattta caccagattg taaatatcct gttgtatatg
    33061 gtgaaaaagg catggcaaag attagaataa aaagtaaaat caattatgaa gaagatgtat
    33121 acttaggttt tatagaaaat atgtctgaaa atgtgcttgt tacatataaa gaactgaata
    33181 tagaaaatag tgatactata ttagatataa aggtaaaata cgattttagt tataaattga
    33241 aagatgtatt ggatgaaata aaagctagtt ttccaaatag tatcgatata gaggtaattt
    33301 ctaattttaa tcctgtatat tttgataaag agagtaatct tgttaaaaag cttcagctag
    33361 cttatgaaag ggttacatca ttagatggaa ctccagtaac aactaatgga ggtacgtatg
    33421 caaaagtaat gccaaatata gttccgtttg gaccttcatt tccaggacaa aaaggaatag
    33481 ctcataatcc tgatgaatac atggatatag aagatataat attaaatgca aagatatttg
    33541 caaatgcaat atatgaatta gcaaaggagt agttatgtta gaaataatag gaatgtcagt
    33601 agaagacgct aaaattatag aagattgtgg tgcagataga atagagttag ttagtgcttt
    33661 aactgaaggt ggattgacac caagttttgg tcttatagaa agtgttgtta acagtgtaaa
    33721 gatacctgtg aacgtaatga taagacatca tgcgaaaagt tttgtataca gtaaagaaga
    33781 tataagtata atgcaaaaag atataagtgt ggttaaagag attggtgcta atggagttgt
    33841 atttggtgta ttggataaaa acaatagtat agatgagaaa aatctaaatg ttttattgaa
    33901 atgttgtgat aatcttgatg ttacatttca tagagcaata gatgaatcaa atacaataga
    33961 tagtgttaaa attttgaagg attatgataa aattacgaat atattaacat caggagggaa
    34021 aggaagtata gttgataaca tacaaatgat aaagaatatg atgcttagtt ctaatcacat
    34081 aaaaattctt ttaggtggag gtcttaattt taataatata gaaaagataa aggaattaac
    34141 taaggcaagt aattttcatt ttggtacagc gattagaata aataacagtc cttttgaaga
    34201 tatagataga caaaagctta aacaactcgt aaatataatt tcaagatagt atatgaatat
    34261 aaaatactta gtttaaataa agagagtaag ttaattataa tttgggtata tgaatgttaa
    34321 taggtattaa atatgaaatt attgttgagt atgctttata acttttaagt agttttaaat
    34381 ataaataatg aaagaaaaga tagattatgg aggttttaga gggtttatat ttattaaaaa
    34441 attataaagg tatattggca tataatacac ataatttcct aaaattacca tcttatgaca
    34501 tgaattcaca tattaataaa caattaatgg agatttttgt ggatagaaat aggagtaaaa
    34561 atagctttaa ataaacaaaa acaagagtta ttaacagttt tatccacatt atccacaggt
    34621 gtttgtaata atattaatcc acataagtat caatgtaact aaaaatgata aataattcta
    34681 tcaattgaat agaaaaaatc ataaaagtaa ataataaaaa gaggattatg agagttcgtg
    34741 tagaatatat tattaaagta taaattttct tatactggca taattgaagg gagatgtatt
    34801 tatgaacata attatatctg gaaaacaaat cgaattaact gatgcaataa aaaataaaat
    34861 cgaaactaaa ctaagtaagt tagataatta cattcatcca gacactgatg taaaagttac
    34921 agtaagtgcg agaaaagcaa gacaaaaaat agaagtaaca atagctactg taaatggtcc
    34981 tataattaga gcagaagata tgcaggaaaa tttatacaca gctatagatg ttgtatatga
    35041 taaattaagt aaacaattaa aaaaatataa aaagagatta caagataaac ataaagacaa
    35101 caagagtata agattccaag atgcagagat aaatctagct gatgaacaag aggattatgg
    35161 ggatgaaaat caagaattag taattcaaag acgtaagaaa tttagtgtta agccaatgag
    35221 tgaagaagaa gctgtattac agatggaatt aataggacat gatttttata tgttcaagaa
    35281 catagattca gatgaaatag cagtagttta taagcgtaat aatggtggat atggtataat
    35341 agaacatgaa taaagcaatt tagatttaat catattagct atcgataaat aaattatcga
    35401 tagcttttta aattaatatt aaaagtatag tttttatggt aaaatgaata atagtacaat
    35461 aaagaacgag gagagatgta aaatatgagc tttatggata atttattcaa catggcagat
    35521 aaaaaagaat taaaaaagtt caataaaact gttgatataa tagattcatt agaacctaaa
    35581 tttgaatcta tggcagactc ggaacttaaa aatatgacaa atatatttaa agaaagatta
    35641 gcaaatggtg aaagtataga tgatatactt ccagaagctt ttgcagtagt tagagaagtt
    35701 tctaagagag tgttaggact tagacactac agagttcaaa tgattggagg tatagtacta
    35761 catcaaggaa gaatagcaga aatgaaaaca ggtgaaggta aaactttggt tgcaactgct
    35821 cctgtttatt tgaatgcgct tactggaaaa ggtgtacatg ttgtaacagt aaatgattac
    35881 cttgcaaaac gtgatagaga ccaaatggca aaaatctatg agtttttagg aatgagtgta
    35941 ggcgttatta tacacggtca aaatccaaaa gttagaaaag aacaatatga ttgtgatata
    36001 acttatggta caaataatga atatggattt gactatctaa aggacaatat ggtaatacac
    36061 aaagagcaaa gagttcaaag aggattaaat tatgctatag tggatgaggt tgactctata
    36121 ctaatagatg aggctagaac accacttatc atatctggac ctggagacaa atcaactcac
    36181 ttatattcag atgcaaacac atttgtttta accttaaaac cagatgatta tgaattagaa
    36241 gaaaaagata aggctgtatc tctaacagca tcgggtatac aaaaagcaga agtgtatttt
    36301 aatgttgata atataacaga tatatctcat acagaattat accatcatat aaatcaagct
    36361 ttaagagcac atgtaataat gaagaaagat gttgattatg ttgctaaaga tggagaaata
    36421 gtaatagtag atgagttcac aggtagactt atgtttggta gaagatattc agaaggttta
    36481 catcaagcaa tagaggctaa agaaggtctt aaaatacaaa gagaatctaa aacactagct
    36541 actgtaacat tccaaaatta ttttagaatg tacaaaaaac tttctggtat gactggtaca
    36601 gcaaaaacag aagaagaaga gtttaaagca atctacaaaa tggatgtttt ccaagtacct
    36661 actaataagc ttatgataag ggaagactta ccagattgtg tatacaaaag tgaaataggt
    36721 aaatttaatg ctgtagcaca agaaataatt gaaaggcaca aagtcaatca accaatactt
    36781 gtaggtacag tatcaataga aaaatcagaa ttattatcac aaatactaaa gaaaaagggc
    36841 ataaagcacg aggtattaaa tgctaagcat catgataaag aggcagaaat aatagcacaa
    36901 gctggtagac ttggagctgt tacaatagct actaatatgg ctggtcgtgg tacagatata
    36961 gttctaggtg gaaatccaga ctttttaact aagagagaaa tgagaagaaa tggatttaaa
    37021 gaagaaatag taaatagagt agatactcca atagaaggta tacctgtaaa aggtaatgaa
    37081 attctatttg aagctagaga agagtatgaa aaactatttg aaaagtttaa gcaacaaaca
    37141 caagaagaac aaaaacaagt tgtagaagca ggtggacttg ctataatagg tacagaaaga
    37201 cacgaatctc gaagaataga taaccagttg agaggtcgtg ctggacgtca aggtgaccca
    37261 gggagttcaa gattctatat aggtcttgat gatgacctta tgagattgtt tggtagtgat
    37321 agaatatctg gtattgtaga taaaataggt cttgaagaag atatgccgat agaacataga
    37381 atattatcta agtctattga aggagcacaa aagaaagtcg aaggtaaaaa ctttggaata
    37441 agaaagcatg tacttcaata tgatgatgtt atgaataaac aaagagaaat aatatatgca
    37501 gagagaaaac gtgtattaga aggtgaagat ttacaagaac aaatacaatc aatgactcat
    37561 tctataatag aagaagcagt tactctttat acacaagata aaggatttga tgaagaagga
    37621 tttaaagaac atatgtataa tctgttcttg ccaaaaggta gcatagaaat accagaaata
    37681 gaaaaactta atccagttga aataacagaa aaagtttatg aaatagctat gaagatatat
    37741 acttcaaagg aagaacaagt tggctatgag agaatgagag aagttgagag agtaatctta
    37801 cttcaagctg ttgataacca ttggatagac catatagatg ctatggacca attacgccaa
    37861 ggtattggtc ttcgtgctgt aggtcagcaa gacccagtta ttgcttataa aatggaaggt
    37921 tttgatatgt ttgatgaaat gaataaacat atcaaagaag atactgtaag atatttattt
    37981 aatataacaa tagaaactcc agtggaaaga aaagcagttg tagatgttga aaatctatct
    38041 tctccatcag atggaacact tccaacaagt aaaactgtta aaaaagatga aaaggttgga
    38101 agaaatgact tatgcccttg tggaagtggt aaaaaatata aaaactgttg tggaagataa
    38161 tctcggagga ttaaatgtta aagttacaag agtatagaca tagtatggag cagatggctt
    38221 caaatttaga agaattgagg gtttctcttt gacatagctt cattgatgaa aaatatacaa
    38281 attaatgaag aaaagatgaa taaacaagac ttttggaatg ataatgaagt cgctcaaaga
    38341 gtacttcaag aaaataagtc tttaaaagag acattagaag aatatgaaag cttaaaaagc
    38401 ttactagaag atatagaagt attaattgaa ataggtttag aagaagatga tgattctgta
    38461 gaaagagata tagaaaagtc catagaatca atggaagaaa aattatctga aatgaaaata
    38521 aagactcttc taaatggaga gtatgataaa aataatgcta tattatctat aaatgcgggt
    38581 actggtggct tagatgctca agattgggct caaatgcttt tgagaatgta tataagatgg
    38641 tcagaaagta agggttataa agttaagctc ttagatataa tatcagaccc tgaagcgggg
    38701 ataaaaacag ctacaattct tgtagaagga acaaatgctt atgggtattt aaagagtgaa
    38761 aaaggagttc atagattagt gagaatatct ccatttgacc catcaggaaa aagacatact
    38821 tcatttgcat ctatagatgt aacaccagag ttagatgaaa atatagaagt agaaattaat
    38881 ccatcagatt taaagataga cacatataga gcttctggag ctggagggca acatgtaaat
    38941 acaactgatt cagcagttag aataacacat atccctactg gtgtagtagt tcagtgccaa
    39001 aatgaaaggt ctcagcatct aaataaggac agagctatga gacttttaat ggcaaaattg
    39061 atagaattaa aagagttaga acaaaaggaa aaaatagaag atatacaagg caaatactca
    39121 caaataactt ggggtagtca aattaggtca tatgtttttc aaccatataa attggttaaa
    39181 gaccatagaa caaatgctga gtttggaaat gtagatagtg taatgaatgg gaatatagac
    39241 ttgtttatta atgaatactt aaaaatgaat aaaatagttt aataaatatg cactgtaatt
    39301 aagatatatg tataagaagg ttagtgctta atatgcactt acagcactta ggctgaggac
    39361 gataaccctc agccttcgtt ctgttttgtt atacttatga aaaactaaca ttaggagtga
    39421 ataaattgga tataaatcaa attttaaaaa aagagtttaa tcttagagat gaacaaataa
    39481 ataatacatt aaaacttatt gatgaaggaa atacaatacc atttatagct agatatagaa
    39541 aagaaatgac tggcgaaatg agtgatgtta cactaagaga attttatgaa aagttaatgt
    39601 atttgagaaa tcttcaaagt agaaaagatg atgtagttag actaatagat gaacaaggta
    39661 aattaacaga tgaaataaca caaaatatag aaaaagcaaa aacactacaa gaagtagaag
    39721 atatatatgc tccatataaa caaaagaaaa gaactagagc aacaatagca aaagaaaaag
    39781 gattagaaaa attagcattg tcaatactag agaataattt agataatata gaaatagagg
    39841 caaagaatta tcttgatgaa gagaaagaag ttctttctat tgaagatgct ctaaaaggtg
    39901 ctagagatat aattgcagaa ctagtctcag atgatgctaa gattagaaag tatataagag
    39961 aattagcttt aagagaaggt atgatagtta gtaaaagtgc cactgatgag aaatcggttt
    40021 atgacatgta ttatgattat agtgaagcag taaaaagtat gcctccacat agagttttgg
    40081 caataaacag aggagaaaaa gaaaacttcc taaaggttaa gttagaaata aataatgata
    40141 aagttttaaa ttacataata aacgaatatg taaatgataa aaatttcaaa aataaagaag
    40201 aaatcgtaag ttcaatagaa gattcttata aaagattaat tttcccatca atagaaagag
    40261 aaataagaaa tcatttaaca gaaatagctc aagaaagagc tataagtgta tttggaaaga
    40321 atgttaaaag tttattgctt caaccaccag ttaaagacaa agtagttatg ggatttgacc
    40381 ctgcatttag aactggatgt aaaatagctg tagtagataa aaatggtaaa ctactagatt
    40441 atacaacagt atatccaaca gaccctcaaa atgatgtaga gggagcaaag aaagttttaa
    40501 aaggattgat tgaaaaatac gatatagata taatttcaat tggaaatggt actgcatcta
    40561 gagaatcaga aacttttgta tcagaaatga taaaagaaat agataacgaa gtgcagtatg
    40621 tgatagttag tgaagcagga gcatctgttt attcagcctc tgaacttgca aatgaggaac
    40681 atccagatat aaatgtatca ataagaggag ctatatctat agctagaaga ttacaagacc
    40741 cattagcaga gcttgtaaaa atagacccta aaagtattgg cgttggtcaa tatcagcatg
    40801 atttaaacaa aaagagatta gaagaagtac tagatggagt tgttgaagat tctgtaaata
    40861 gtgttggagt agatttaaat actgcatcat actccctact agaacatgtt gcaggaataa
    40921 gtaaaactat agcaaaaaat ataatagcat atagagaaga aaatggagat tttacgtcaa
    40981 gagcacaatt gaaaaaagta aagagactag gaccacaagc atttactcaa tgtgctggat
    41041 ttatgagaat cttagagggt aaaaatccac tagataatac aggtgtgcat cctgaaagtt
    41101 atgatatatg taaaaaaatg attgagataa ttggatattc tttagatgat gtaaagaata
    41161 agaatatatg tgaaatagat gaaaaaataa aagaaattgg cttgagagaa ttaagtgaaa
    41221 aactggaagt agggcaagtt acgttaaaag atatcataac tgaaatcaaa aaaccaggaa
    41281 gagacccaag agaagaaggt ataaaaccta tacttagaac tgatgtctta aaaattgaag
    41341 atatacaaga gggtatgact ttaaaaggta caataagaaa tgttgtagat tttggtgcat
    41401 ttgtagatat tggaataaaa aatgacggat tagttcataa atcagaaatg agtaatagtt
    41461 ttgtgaaaga ccctatgagt attgttacag taggtgatat agtagatgta aaagtcattg
    41521 gaattgactt aaacaaaaaa agagttgcct tatcaatgaa aaaatagata agtttatgta
    41581 tggttatagt acttaaattc tatgtttgta aatgaggtta ctcgagtgta taaatgttaa
    41641 aaatttgtaa aagtatacag taagaaaata tattaaaata agaacgatag tcttgaaaat
    41701 caggaggaaa atgaatgatt tttataaaaa atggtaaaat aaataccata acaaatggga
    41761 taattcatgg agatatactt atagatgaag gaaaaataat agaaattgga gaagatttga
    41821 tagctccttt agatgtagag gtaatagatg ctagtaataa acttgtgttt cctggattta
    41881 tagatgctca tactcattta ggtttgtggg aagatggtat agggtttgaa ggagcagatg
    41941 gaaatgaaga gactgaccca ataacaccac aattaaatcc catagatgga attaatccaa
    42001 tggatagaac ttttaaagaa gcttttgaag gtggaataac ttctgtttgt acaacccctg
    42061 gaagtgcaaa tgttatgggt ggtcaatgta tagctataaa gacatgtgga aaaagaattg
    42121 ataaaatggt aataaaaaat ccagttgcat ctaaaatcgc ttttggagaa aatccaaaga
    42181 gctgttatgg tcaggatgat aaatctcctc aaactagaat ggctatagct gctttactta
    42241 gagaaaacct aaaaaaagca gaagaatatt tagaggatat tgatatgtat gagagtcatg
    42301 atgatgaaga ctgtgaaaaa cctgaatatg atataaaaat ggaaagttta ataccagttt
    42361 taagaagaga aattcctttt aaggcacatg ctcatagagc agatgatatg tttacagcaa
    42421 taagaattgc aaaagaattt aatttaaagc ttacattaga ccattgtaca gaaggtcatc
    42481 ttattgtaga tgaattagtg gaagaagggt ttcctgtaat agtagggcca tctttgtcag
    42541 aaaggtctaa atttgagctt agaaatttga catttaatac agcaggaata ctttcaaatg
    42601 caggtcttga tgtatgtata atgacagacc atccagtaat accagttcaa tatcttccaa
    42661 tatgtgcagg tattgcagtc aaacatggta tgaaagaaga aaaagcaata gaatcaatta
    42721 cgataaatcc agctaagact ttaggaatag aagatagagt aggctctata gaagttggta
    42781 aagatgcaga cctagtaatt tgggataatt ctccactaga gattcaaagt aatgtacttt
    42841 acactataat aaatggcaaa gtagtgtatg agaaaaaata acttgacaat tattaaaaaa
    42901 ttaactaata taagagtgta aggaaaatta aaaaatcaaa gaagatcttc ggggcagggc
    42961 gaaattccct accggcggta tagcccgcga actacttaag tggttgattt ggtgagattc
    43021 caaagccgac agtaaagtct ggatgagaga agatatttat ggaagataaa taagtttatt
    43081 ttagtttgtt taaactatat ccataaaaac tcgaagatag ggtcttcgag ttttttgttt
    43141 ttcctaaaaa atataaacat attgattagg gggaaataat tatgcaaaac acagccaaaa
    43201 gaggcaatat gatttcaaca agaactttag tagtaatgtc aattttatct gcaatatctt
    43261 atttattaat gtttattcaa gcaccaatac caggtatatt tccagatttc ttaaaaattg
    43321 acttatcaga tattccagca atattcggag gaatgtctct aggaccattt gttggatttg
    43381 gaatagttgt agtaaaaaat gtgttacaag caataacagc aacaacaact ggaggaatag
    43441 gagaatttgc aaatatatta attggtggtt cttatgtaat gatactttgt tattcatata
    43501 agagaagtgg agatttaaaa ggtgtattga ttggttttgt attaggaaca atatctatga
    43561 ctataattgg ttcattagta aattattttg taatgttgcc actttatggt caacttatgg
    43621 gactagatgc tataataggt ttaggttcag ctataaatcc tcaagttcat gatttattca
    43681 cttttgtaat ttggatgata gctccattta atgtgctgaa ggctgttata ctatctttag
    43741 taacattgcc actttataaa aaaatgggaa atgtaataaa gaaataatta gacaagaaaa
    43801 tataaaatta aatgtattga atagccataa tttatttata acttcagtcc tatattgtga
    43861 ttgatatatt aaatatatta tggctttatt aatttatcaa aaaatgtata taaaataaga
    43921 aatatttaga caaatttaaa ttttaaaata aaggaagaat taaaacgatt aactattaaa
    43981 atatgaaaaa ggtatctgca atatacagag cgaatttata ataaataaaa aataaagtta
    44041 ttattaaaaa aatataaaga ttagtaatca aatttttaat aataactaat ttaataatga
    44101 tgggagtgta tattcatgaa cttatctaaa aagataaaaa aattattttt agatgataaa
    44161 gggtattatt ttaatagtaa ttggaaagat attcatattg gtatttataa tacaaaatta
    44221 ggagattctt taaagtatat cactaatgaa tatattgaaa atctggaaag ggtaaaatat
    44281 gactatcgtg aattaaaaaa tatagaaaat caaactgatg gtatgtgtat tttagcaata
    44341 aggcagaatt acaaggcatt agagtatgta aaaaatcaaa ccgaagaatt atgtttagaa
    44401 gcaataaagt ataattataa agcacttgaa tatgtaaaag agcaaacaga atatatatgt
    44461 cttgaggcta taaaaaagga ttgtaatgca cttaagtatg tacgaaataa aacagaaagg
    44521 cttattataa aagtaatacg tcattcttcc aatatagatg ttgtaagtat actaaaggct
    44581 ttagagactc aaacaagaag aatatgttta gaagcaatta aaaaagatgg caggtgtctt
    44641 gcatacgtta gagaacagag tgaagaatta tgtatagagg ccattaaaca aaattataaa
    44701 gcattaaaat atgtagaaaa tcaaacggaa aaaatgtgta tagaatccgt aagacaaaat
    44761 ggtatggcat tacaatatgt aaataaacaa actgataaaa tatgtataga agctgtcaaa
    44821 caagatggaa gaagtctaca atttgtcaat aataagacag aagaaatatg tataaatgct
    44881 ataagatatt taaataaaaa atataatatt aaagatgtac taagttacat agataagtat
    44941 acagaagata tatgtataga gattgtaaga caaaatggaa aaatgcttat gtatataaaa
    45001 aatcaaacag aaaaaatgtg tattgaagca gtaaaagaga actataagtc tcttaagtat
    45061 gtaaaagagc aatctgagag aatatgtaaa gaagcattga agcaaaacca taaagcaaaa
    45121 gagtatgtaa aaattgctat tgatgattgt atataaggtg tagatacagc catcaatagt
    45181 gaaagataaa aaaagataaa gacaagtact ttataataat ctaggcttat actataatta
    45241 attaagcagt gatataaatt cacatgacga ttatatcaaa atggagatga attgatggca
    45301 aaaatatatt tagaaaatga aaataaaact agagaaatag gatataaatt aggtaaactt
    45361 ttaaaagaag gcagtgttat ctgtttagta ggagatttag gagctggtaa aactacaatg
    45421 acacaaagct tggcagattc attagggata gaagattata taacaagtcc tacttttact
    45481 ataataaatg aatatgaagg aaaaatacct ttgtatcatt ttgatgttta tagaataggt
    45541 agtagtgacg aaatgtatga tattggttat gatgaatatg taaattcaaa tggaatctgt
    45601 ataatagaat gggctaatct aatagaagat atacttccaa aagaatattt gaatatagaa
    45661 ttgagatata aagatgacgg aagagaaatg atattaactc caaaaggaga gttttataaa
    45721 gagatagttg aggagttgat taaataatga aaatactagg tatggatacg tcttctatgg
    45781 cagcaagtgt agcagttgtt gaagatgata acttaatatg tgagtttaca gtaaacaaca
    45841 aaaaaactca ttcacaaaag cttatgccaa tgatagaaaa tatgttgagt atgagtgatt
    45901 taagtataaa agatatggat ttattagctg tatgtatagg tccaggctcg tttactggac
    45961 ttagaatagg tatggccaca gtaaaagcta tggctcatgt aaataatata ccaataatag
    46021 cagtaaattc tttggaatct ctagcaaata acataaattt ctgtgataga aagatatgtt
    46081 gtatattaga tgcgcagaaa aatcaagttt attcagctaa atacaagttt gaaaatggag
    46141 agatgataga attagatggt gtagatgttg tagagtttga tgctttagta gatgaaattg
    46201 tatcaactaa tgaagaattt ataatagttg gagaagctgt atacaaatat aaagataagt
    46261 tagagaatat aaaaaatata aaaatacctt caccagctaa taatgtatct aacgcaggaa
    46321 gcttatgctc tttagcatta aataaatata ataaaaatat agatgtacat acttgttata
    46381 cgataaatcc tatgtatatc agaaaatctc aagctgaagt acaatatgat gaaaaaatga
    46441 agaggctaaa taatggaaga taatacaaaa ctaatagtag atgatataaa aatagaagaa
    46501 atgactacag aagatataga tgaagttttt gaagtagaaa aaaattgttt tgaagattat
    46561 tggtcaaaag agtcttttag aaaagagttg tctaatgaag tagcaaggta tatagtagct
    46621 aagttaaatg gaaaaattgt cggatatgtg ggaatttggc ttatacttga tgaagggcat
    46681 ataaataatg tggctgttca tagtgactat agagggaaaa aaatagggga caagttgata
    46741 aaaggcatag ttgatttatg taaagataat aatattgcat ctatgacatt agaagttaga
    46801 gcatcaaata aaatagcaca aaatttatat agaaaatatg gatttaaaat gggtggaata
    46861 agaaaagaat actacagtga taataaagaa gatgcaatta taatgtggaa ccaattaaaa
    46921 gaggtgtaga gtttatgagt gatataataa cattagctat agagagtagt tgtgacgaaa
    46981 cagctgcatc agttttaaaa aatggtagag aagtactttc aaacataatc tctactcaaa
    47041 tagagacaca taaaaaattt ggtggtgtag ttccagaagt ggcttcaaga aaacatgtgg
    47101 aaaatattga tatagttgtt caagaagctt tagacaaagc aaatataggt tttaatgata
    47161 tagaccatat cgcagttaca tatggacctg gactagtagg tgctttattg gttggtctat
    47221 cttatgctaa agcacttgca tatactttga atattccact tgtaggagta aatcatatag
    47281 aagggcatct aagtgcaaac tatatagagc ataaggattt gaaacctcct tttataacat
    47341 taatagtatc tggaggtcat actcacttgg ttgaagtaaa agattatggc aagtatgaaa
    47401 ttttaggaaa aacaagagat gatgcatctg gagaagcatt cgataaaatt tcaagagcaa
    47461 tgaatttagg ttatccagga ggacctatta ttgataatct agccaagaag ggaaataaac
    47521 atgctataga gtttccaaga gcctatttag aagaagatag ttatgatttt agttttagtg
    47581 gattaaaatc ttctgtattg aattatctaa atgggaaaag aatgaagaat gaagaaatag
    47641 tagttgaaga tgtagcagca tcttttcaag aggctgtggt agaggtttta tctactaagg
    47701 cactaaaagc agtaaaagaa aaaggataca atatcataac tctttctggt ggagttgctt
    47761 ctaattcggg gcttagagct aaaataacag agcttgctaa agacagtggt attactgtta
    47821 agtatcctcc tctaatttta tgcacagata atgcagctat gatagggtgt gcaggatatt
    47881 ataattttat aaacgggaaa acgcatgata tgagtttaaa tgcagttcca aatttaaaga
    47941 taaatcagta gagttagata aatttgtaaa tataaaagta ttgtttcaaa aaagtaagca
    48001 gaagtgaaat taaatataat aaaaatcaat atagtatata ttaaaacttg aagtaaaact
    48061 atttataatc tttatattcc aatgaattgc aacacatttt aggatataca ggttgtcttt
    48121 ggcttagatt tgcttcaagt ttaatttttt ctatagaaag attattttaa aaagtgggta
    48181 atataccctt ttttttcatt cttaaaaagt tttatactaa ttatagaaag attaaggagg
    48241 ggaagaaatg agtcaaagta aagaagacaa aataagaagt attttggaag caaaaaatat
    48301 caaatcaaat tttcaaaata aagaaaattt aagtgaattt aatgaaaaaa aagcaagtaa
    48361 aagagcagaa gacttattag atgtatatta taatacatta tctactgcag atatggaatt
    48421 tccatattgg tataatagag aatatagaaa atcagatggt gatataccag tagttagaag
    48481 agctaaagct cttaaatctg ctttttcaca tatgacacca aatataatac ctggtgagaa
    48541 aatagtaatg caaaagacac gccattatag aggttctttt ccaatgccat gggtaagtga
    48601 aagtttcttt gttgctcaag gagaacaaat gagagaagag gcaaagaaat tagccagtaa
    48661 cacagctgat gaacttacaa aatttgggtc tggcggagga aatgttactg aaagttttgg
    48721 aaatgtcgtt tcaatagctg gtaaattcgg aatgagaaaa gaagaagtac ctgtacttgt
    48781 aaaaatggca aaagaatggg ttggaaagtc tgttgaagat ttaggttttc actatgaaaa
    48841 aatgatgcca gattatgatt taaaagaaaa cctaatgagt acacttatat gtatgtttga
    48901 ttcaggatat acacttcctc aaggtagaga agttataaat tatttttatc ctttaaatta
    48961 tggattagat ggaattatag aaatggcaaa agaatgtaaa aaggcagttg caggaaatgc
    49021 atctggagat gggcttattg gtatggaccg tctatatttt tatgaggctg ttattcaagt
    49081 tattgaagga ttacaaactt ggattttaaa ttatgcaaaa catgcaaaat atttagaaag
    49141 tatagagaca gatttagaag ctaaaaaaga atactcagat ttagtggaga tattagaaca
    49201 tattgcacat aaacaacctc gtacatttag ggaagctctt cagttgactt atacaattca
    49261 tatagcatca gtaaatgagg atgctatatc tggtatgtct ataggccgtt ttggtcaaat
    49321 tttatatcct tggtatgaac aagatataga aaaaggatta attacaaaag aagaggttat
    49381 cgaattatta gagctttata gaataaaaat cacttgtatt gactgttttg cttcagcggg
    49441 cgtaaatgga ggagtactat caggaaatac atttaatact ttatctatag gtggattaaa
    49501 agaagatggt tctacaggag ctaatgaact agaggagtta ttattagaag caagtatgag
    49561 atgtagaact cctcaaccta gtttaactat gttatatgat gaaaaacttc cagaagattt
    49621 cttaatgaaa gctgctgaat gtacaaagct tggttctggt tatccagcct gggtaaacaa
    49681 ctcaaatgga acaacattta tgatgaaaca atttgctgat gaaggtatga ctgttgaaga
    49741 agcgagagca tttgcattag gaggatgttt ggaaacgtct ccagggtgct ggaaacagtt
    49801 aactttaaac gggaagacat actctattgc aggtggagca ggtcaatctg ctggctctgg
    49861 agttcacttt atagctaatc ccaaaatttt agaacttgtt cttatgaatg gtaaagacca
    49921 tcgtatgaat atacaagtat ttgagcctca taataagcca ttagatactt atgaagaagt
    49981 catagaagta tttaaagatt attataaaca agcaataaat gttttagaaa gagcaaataa
    50041 cattgagtta gatatatgga gaaaatttga tacttctata ataaattcac tattaaagcc
    50101 agactgttta gacaaaggtc aacatatagg aaatatggga tatcgttata atgcaacatt
    50161 aaacgtagaa acttgtggta ctgttactat ggtcaattca tttgcagcac ttaagaaact
    50221 tgtatatgat gacaaagcat ttacaataga ggaaatgaag gatgccatat taaataattt
    50281 tggatttaaa gatgcattag aagtaggaaa ttattctatg gcagaccaag taaaagtaga
    50341 taagactggt aaatatgatg ctatttataa ggcctgtctt gatgcaccta aatatggaaa
    50401 taatgatttg tatgcagata atattcttaa aaactatgag gtatggttat caaaagtatg
    50461 tgaagaagca caatctttat atgctaagaa gatgtaccct tgccaaatat ctgtttctac
    50521 acatggacca cagggagctg ctaccttggc tactgcagat ggtagactaa gtggaacaac
    50581 atattcagat ggttcagtct ctgcatatgc aggaacagat aaaaatgggg tatatgcatt
    50641 atttgaatct gcaactattt gggaccaagc agtagttcaa aattctcaga tgaatttaaa
    50701 acttcatcca acaactataa aagggcaaca aggaactaaa aaattattag atttaacaag
    50761 aagttattta agaaaaggtg ggttccatat tcaatataat gttgtagatt cagaaacatt
    50821 aaaagatgca caaaaaaatc ctgacaatta tcgtcaatta atggtacgtg ttgctgggtt
    50881 tactcaatat tggtgtgaat taggtaaacc aatacaagat gaagtaattg ctagaacaga
    50941 gtatgaaggg gtgtaaaata tgagaaagca tagtgattgt atgaattttt gtgcagtaga
    51001 tgcaaccaaa ggaatttgta gattatcaaa acaaatgatt aatttagatg atgcagcatg
    51061 tccagagata aaagtaatgc caaaatgtaa aaattgtaaa aattttgttg aagctaatga
    51121 tgaaggtata ggcaaatgtg ttggcctaga gaaagaagac tgggtatatt caacattgaa
    51181 tgcaattact tgtgaaggac atgtgtttaa tgagtagtca aaagcaatta gaaggcatga
    51241 ttttcgatgt acaaagcttt tcagttcatg atggtccagg ttgtagaaca actgtatttt
    51301 taaatggatg tccactgagt tgtaaatggt gtgcaaatcc agaaagttgg actgtaagac
    51361 cacatatgat gtttagtgaa ttatcttgtc aatatgaaaa tggatgtact gtatgtcatg
    51421 gtaagtgtaa aaatggtgca ttgagcttta atcttgataa taagccagtt atagattgga
    51481 acatctgtaa ggactgtgaa agttttgaat gcgtcaactc atgttattat aatgcgttta
    51541 aattatgtgc aaaaccttac actgtagatg aacttgtgca ggtaattaaa cgtgattcta
    51601 acaattggag aagtaatgga ggagtaacat ttagtggagg tgagccacta cttcagcatg
    51661 aatttttaca tgaagtatta ttaaagtgtc atgaggtaaa tatacacact gccattgaaa
    51721 cgagtgcatg tgtatcaaat gaagttttta ataaaatatt taacgatatt gattttgcat
    51781 ttattgatat aaagcatatg gatagagaaa aacacaaaga acaaacaggt gtgtataatg
    51841 atttaatatt agaaaatata tcaaaccttg caaattctga ttggaatgga agattagtac
    51901 ttagagtacc agttatctct gggtttaatg atagtgatga aaatataagt gatattatat
    51961 cttttatgca caaaaataat ttggtagaaa ttaatctatt accatttcac agattaggag
    52021 aatcaaaatg gattcaatta ggcaaggaat atgagtattc tgataagggt gatgttgatg
    52081 aaggtcatct tggagaatta caagatatat ttttggataa tggtatagct tgttatgttg
    52141 gtcatgagac agctttctaa aattaaatac aagttttaat taaaaaagga tgttacacta
    52201 aaagctagag ttacatcctt ttttatgtgg tttttatgta gaaataatta agtaaagttt
    52261 tatatatttt atatattgtt tatattgctt tatgtccata aatattgctt taaatatact
    52321 ttatatattt tttatagttt aaattacagt tagagaatat attacgttta ctttattgaa
    52381 gcagaagttt tgtggtaaaa tactactatg aaaaaattta atagaatata ttttagaaac
    52441 aactaaaaat aatagttagg aggaagacat ctatatgaac aaatcatgga gcaacttgat
    52501 tattaagaat aaagacaaaa aagtacgttc agggtggatt attatagctg ttatggctac
    52561 cttttacata tttcagtatt atttaagcat gatacttgtg gaaataataa gaaaaatcct
    52621 ggttgctaca ggggacatta atttaaaaac aaactatttt tcagaatatg ctaattggtt
    52681 aaatgatgtt gggttacaga ttgtatttca aattctaaca gattcactta tgattattat
    52741 tcctataatt gtatggagat ttattatgaa aaatcctatt agtgaaatgg gattacattc
    52801 ttatagaatt aagaaaaaag aaggatatgt aggaatgtta ttaggaatat ttaattgtac
    52861 agtaatcttt attataacaa taacaattgg tggtggtcat gttacttcat gggtaccaaa
    52921 aatttcacct ttaacagttt cttgaatact tgtctttatt ttagttgctt ttgcagaaga
    52981 aattttaaat cgtggttttt ttatggcagt tttacgaaga tgtaaaaata tttattttat
    53041 aatgattgtt ccatctgtta tttttgggtt gattcatata tggaatcctg atgttacttt
    53101 tttgtctgta attaatatta taattattgg gattcttttt tcatatatgt ttataaagtc
    53161 gtcgaatata tggatgtgta taggttatca ttttacatgg aatgtatttc aggggattat
    53221 atatggtatg cctgtaagtg gacttcaggt tccagggatt ataactacac aaatcactca
    53281 tggtaatcta ttaaatggtg gtatgtttgg tattgaaggt ggaattttga ctacttttgt
    53341 taatctactt agttttatat ttgtatggta ttactataga gattctaagt atgattttgt
    53401 tagtgataaa gtaaatgtga ccaatatcaa gaattagttg attataataa attttaataa
    53461 tatcttctaa gcttaaagta ttctgtagga ttgttggaaa tttacaaaaa tataaaaata
    53521 acttggatat tctatttact ccaagttatt tttatattct tttgtaaata gaaatggaac
    53581 ataaaaaatt aaaacaacca tagatactat tagtatatca tggtaagtga tagttgattc
    53641 tttagaattt gtgataagaa aagcactatt atttaaaata tgaattatag cacaaaacca
    53701 gatgttctta gtttttatat aaagatatcc taaaaatatt gaaattccaa ctatatgtat
    53761 cgaacgtaat attaatccta atattggtgt ttcaggtgta tataatgtaa atattagtgg
    53821 taagtgccac aaactccaac aaatacctaa tattataact cctagttttt taccaaattt
    53881 attaaaaaaa atattctgta aaaaacctct ccaggcatat tcttcactaa aaaaaatata
    53941 aatagtagtt aatgatgtta ttggagtaaa tataaatttt atgataccac tataattagg
    54001 ttgagaccct tgtagtatta atataaatga tgttggaaca attacagaaa tcataaagta
    54061 aataattaac aaagaaccta gtttaatatt ttttatagga tataaatttt ttttatttga
    54121 tgaatatatt ataattgata aactacttat aaaagttaat attaggttta taattataaa
    54181 ttcattatta tttattagat ttaataactt aagaacaatt aataacgaat aag
//
LOCUS       DAEPKC010000013        53395 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.013, whole genome shotgun sequence.
ACCESSION   DAEPKC010000013 DAEPKC010000000
VERSION     DAEPKC010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 53395)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53395)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53395
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.013"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            208..1536
                     /locus_tag="KR294_000884"
     CDS             208..1536
                     /locus_tag="KR294_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0238990.1"
                     /translation="MMKIAVITTEFLKEFVDNSIKKLNINAEIEIYIYRDFSHVGDLY
                     LEIEDRFDGFAVSGPIPKKAITKKAGTIKKPLVDFGTDLQSYYDMFLKLIFKYNTLDF
                     SRAYFDLTDWADNPKDISYYLSNGTFGDLMDSIDENASKMSLSDIAKLEKKIAKKHIN
                     LWNEGKIDFSTTRFSSIVPMLQNAGVNFHFIYPDIDLLKNTFNNLIKDIHLHRMKGNQ
                     PSVIYITVKDTNYDDSTLDQVYKILNSIKKDKLTDFIIEKNSNSFKIFTKCETIKSLT
                     KNFTACYIKESIENSTNIKVCVGYGIGNDIKQAMSSAISANKESKINHLNYSFLVNEN
                     YETIGPLLCDKLLTVSNKVTPHINTIAKSSKLSTLTIQKIISVTEILQRDEVTPKELS
                     SCLNVTVRTANRFLSSLLKSGNATILYEKQNSTKGRPERVYKLFISENKY"
     gene            complement(1664..2854)
                     /locus_tag="KR294_000885"
     CDS             complement(1664..2854)
                     /locus_tag="KR294_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH0238991.1"
                     /translation="MKNFFKEAQSIEGEIIRWRRYLHENPEIGCNLPKTVTFVTSTLE
                     KMGYSPKLTSNNGIVAVLDSKNGGKTLLLRADMDALPIMEETDLPFKSKNKDASHSCG
                     HDNHTAMLLGAAKILMDNKHLLKGRVKFVFEPDEETTRGAKSMIDDGILENPQVDAAM
                     AFHSMVGKFLNTGQVAYSRGPAMASADIFEITVEGKATHGASPEFGVDPINIMSHIQI
                     ALNTILSREKPQKEPVVLTIGMFNAGSVPNAIPNKASMSGTLRTFDQSVREKLKNRII
                     EISTGIAKSFGGNAKVEFKMGTPAVINDLDVGDEIVSYVKEVIGNENVIDFPSAMGSE
                     DFSEILLRVPGVFLWIGMGSISQGYNFGMHNPKAIFNEEGLVYGSALFAHCAVKWLEN
                     NFSR"
     gene            complement(2960..4339)
                     /locus_tag="KR294_000886"
     CDS             complement(2960..4339)
                     /locus_tag="KR294_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH0238992.1"
                     /translation="MIGSISINEIDKKRFKLDDLSKKIWENPEKAFKEFKACENTANF
                     LRSEGFDVEVGVGGLATAIRASFGSGKPVIGFMGEFDALPGLNQKVSTKQEAFELGAY
                     GHGCGHNLLCTAHVGAVVGLKREMIENNLSGTIVFYACPGEEQLTGKGFMARGGAFEG
                     LDLAINFHPNKISEATIGTSTAVNSVKFHFKGKTAHAGSDPQNGRSALDAVELTNVGA
                     NYLREHVTSDVRIHYTITDGGVAPNIVPDKASVWYYTRALSREAVESTYERLVKVAKG
                     AAMMTETEVEVEFLGGCYNTLNNHVLANLVSECMNEIKQEPWTREELDFAAELDRQSP
                     QQYKAMISKYNLPEGTHLYYGGGNVTNFNSYGSTDIGDVMHIVPTAYFFTGCTNLGAP
                     GHSWQFTSCAGSSIGEKGMIYASKIMAMFGAKILNNPEIAKKAKEEFDKSMNGKTYKC
                     PIPDDIPTP"
     gene            complement(4370..5578)
                     /locus_tag="KR294_000887"
     CDS             complement(4370..5578)
                     /locus_tag="KR294_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0238993.1"
                     /translation="MENFWNPLTCFTVCVMIYAFSEFLSKKTKGAISTLLFVCIIFLL
                     GFWTNILPKDITGASGILAAMSNFGIALLITNLGTLINLEDLCHEWKTVVIALVGIVG
                     IGVGCLTVGSMLFGREYALIAAPPIAGSTVAGIIVTTVAEAANRPELAAFVILVLSFQ
                     KFFGIPITTYCINKELKFKRDNGDFLKDESKSNFKLPSMRIFKEDLGKKSSTLVYLAK
                     LSFVAMIGNFVGLATLIPGFTPANYYLNPNIACLLVGLIFTRIGFLEKGILDKSQSNG
                     IIMFGCMLMLPGGLAKVTPTALFGMIIPTIGILVVGSVFIILFTAIVGKLLGYSPRMS
                     AAIGVTCMLAYPATQIISNEGIDAMEGTEEEKQRATDYLLPKMIIGGFVTVTIASVAF
                     ASIIGPIIFG"
     gene            complement(6603..8057)
                     /locus_tag="KR294_000888"
     CDS             complement(6603..8057)
                     /locus_tag="KR294_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HBH0238994.1"
                     /translation="MNIKDTFFWGGSIAAHQCEGSWDSDNKGPAIMDFVTKGSYETPR
                     VITDKIEEKLDYPSHNGIDFYNRYKEDIALFKEMGFSALRISIDWSRIFPNGDDENPN
                     ELGIKYYEGLIDTLIENNIEPIVTLYHFELPMNLVHKYGSWNNRKLIDLYLKYSETVI
                     RRFDDKVKYWVTFNEMNHIDPQTEHSDIFTYMIAGIKYSEIENKVQTLANVGYNMTLA
                     GVKVAKLAREINPNNKIGCVFGLNPIYPYNCNPSNVLNAFLDNDRDYYQIDAMCNGKF
                     PQYKLKEYEKNNITIEVTDEDKKAFKEGKLDFIGLNYYFSSVSTPKENLSGDKSLFGG
                     IQNPYLEQSKWGWAIDPIGLRFTLNYIYRKYQLPILITENGLGAYDKIEEDGTINDDY
                     RIEYLSKHLSQMKSAIEEDNVECFGYLMWGPIDLVSATTGQMSKRYGFIYVDLDDEGK
                     GSFKRYKKKSFDWYKEVIKSNGEVLDFSTDIVVG"
     gene            complement(8077..9948)
                     /locus_tag="KR294_000889"
     CDS             complement(8077..9948)
                     /locus_tag="KR294_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBH0238995.1"
                     /translation="MKYKDLNENIIKLIGGKENIKSVAHCVTRLRFTLNDRSIAQTEE
                     IKKLKGVIDVVSNDVAYQIIIGTHVVDVYNEFMSMIGLSSSESSIKSERKKGIRGIKG
                     IFNSIFVVVSETMTSVIEVLLAAGILASILALLNMSGILQSDSPTYQILDTLRSATFH
                     FLPVLIAIASAKRLNVNPYIAVVLAVTLLSSSIDGVEGLSLFGINLQATTYANSFIPI
                     LLGVWAMGIIIEGLKKILPKALHYFLVPVLSLIITLSVTLTVFGPIGMWIGDGLNYAC
                     MFLIDTLGNWSVVALYAALQPLLIVFGAANFTMPISLNSVTTLGYDPIFMGAATISDI
                     AVCGAMFGYFLKTRNKEQKQLFGTVSFSALMGVTEPSVFGVFMKYRRPFVAVMIGGGI
                     GGLIAGLAQVKTYGMVWGLAALPTYLVGGEVSNFTFMIISVVVSFVAATAASYLLGIP
                     SDEKEEVKGDNEKELELIINENNSRTISIGNVAKGQVIALGEVNDKAFSSGALGKGVG
                     VIPSESKSTVISPVDGTITIVFPTKHAYGIVTDEGLEILIHIGIDTVNLDGKFFESLV
                     TQNQRVKKGDALAVFESDKIIEEGFDSTIITVVTNTSDYLDVISSNDESEELLTVIV"
     gene            complement(9938..10798)
                     /locus_tag="KR294_000890"
     CDS             complement(9938..10798)
                     /locus_tag="KR294_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBH0238996.1"
                     /translation="MKIIQILNNNVALVKRGKNEIIVFVKGIGFKKRVGQVINENEIE
                     RTYILDSYDMLEHFSYLLQNSDSNNIVLINEIIEYGEKALNIKASDYLSLTLLDHLEF
                     LLKRCEKNQFIKSPLVWNVKRFYPKHFEIGMHALKLIGDSKGINLPDDEAVSIALHFV
                     NMEVNKESHDSTIVELRTLADIVSIIKYHFNVELDETSTNYMRFTTHLQYFIQRIMSD
                     EASIDEDNSIDLYKQVSQLYPKSFGSVQKIRKYIKSQFNVDISISEETYLMLHINRVT
                     QRLEAKSDEI"
     gene            complement(11495..11899)
                     /locus_tag="KR294_000891"
     CDS             complement(11495..11899)
                     /locus_tag="KR294_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3139 domain-containing protein"
                     /protein_id="HBH0238997.1"
                     /translation="MKKYKVIFIVLIIGIISVTGFVVYKNCIKPWKDAETYIDKYMVK
                     QDISKDNIKSITKEKAKKASYEGILYKVYYKDDPRYEYQYFYSDNYYALYVNKVMLQI
                     YDMENNNKLLRSNEELKSVKYPLIYLKYKPDK"
     gene            complement(12091..13278)
                     /locus_tag="KR294_000892"
     CDS             complement(12091..13278)
                     /locus_tag="KR294_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HBH0238998.1"
                     /translation="MSKIVFFSIPAYGHTNPTIEVVRELVDRGNEVLYYSFNEFKDKI
                     EGAGAKFICCDKYLPELLPGDEKKIGKDFPGLIEMIVDTTISLDEKVCRELKDFNPDC
                     IVSDSLSFWGKLFAQKLNIPYVCSTTTFAFNKHTAKLMKQNFIEIIRMIFGVRRINKK
                     IKLLQRKGYEVKNFISIVSNDNDTDTIVYTSKEFQPMVETFSSKYSFVGPSVSKLIIE
                     PKERKRKLIYISLGTINNKNVSFYKNCISAFKDSDVDVIMSVGRSTDIKSLGNIPNNF
                     EVKNSVEQIAILQKTDVFVTHSGMNSVNESLYYGVPMVLFPQHSEQRMVAKRVVHLGA
                     GIMLKEDKSESIKKAVFQVINDNEYKENATKLSKSFYNAGGSKKAADVILQIICNSRQ
                     VDI"
     gene            complement(13310..13735)
                     /locus_tag="KR294_000893"
     CDS             complement(13310..13735)
                     /locus_tag="KR294_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0238999.1"
                     /translation="MINENLKSLRKINQYTQEELAEKLNVSRQSIAKWESGESIPDIC
                     SCIKLAKLYNVKLDDLVNHSEEKTGIIVPPKGKFFFGAVVVGERGQIVIPKEAREVFN
                     INAGDKLLVLGDEERGLGIVHQRDLINFIGHVGVVRKEE"
     gene            14193..14942
                     /locus_tag="KR294_000894"
     CDS             14193..14942
                     /locus_tag="KR294_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440038.1"
                     /note="N-terminal region resembles flavodoxins. C-terminal
                     ferrodoxin region binds two 4Fe-4S clusters; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EFR1 family ferrodoxin"
                     /protein_id="HBH0239000.1"
                     /translation="MILYFSGTGNSRYVARKIAQELNDELISLNQLIKEEKTDELISA
                     DKPFIFVCPTYAWRLPIVVTDFIKETKFLGSNRVYFVMTCGGDTAKSINYIQKLCKYK
                     EWQLKGMAEIKMPENYIALFSTTDKETSKQMIKEADKQIYRIISDIRNENEFETITPS
                     GLGGTIKSGIINTVFYKTIISAKGFHYTDKCIGCGKCVELCPLNNINLKNKKPVWKNN
                     CTHCMACICGCPTEAIEYKNKTQNRERYYLE"
     gene            complement(15108..15473)
                     /locus_tag="KR294_000895"
     CDS             complement(15108..15473)
                     /locus_tag="KR294_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBH0239001.1"
                     /translation="MEKECQQRMQEITSKFKECRKAISAMGDETRQLILIALLESDFN
                     GIRVGEITKKTHLSRPAVSHHLKILKEAEIVNLRREGTKNYYYLDSKKSQWKSLTELI
                     NLIFVGIQHISENDIRKGD"
     gene            complement(15489..16265)
                     /locus_tag="KR294_000896"
     CDS             complement(15489..16265)
                     /locus_tag="KR294_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBH0239002.1"
                     /translation="MKYQHIIEVDKELCIGCGLCKNDCPVNNIIIENKKSVIKKQDCL
                     MCGHCAAICPTKAITLTGFDEPPIELTNKPKLDSDELLMAIKSRRSIRKFKDKEVSSE
                     IIKQIIEAGRYTPSAKNSQDVSYIVLDNKKSIYENEAVKFFRKIKPIANIAIKYSKEV
                     EIDDNFFFKHAPIAIMIITKDKISGSLAASNMALMAESYGLGVLFSGYFSDVANNSPK
                     LKKLLGLKRSNHVLTTLVIGYPDVKYRRTAQKEVATVRYL"
     gene            complement(16712..18139)
                     /gene="ascB"
                     /locus_tag="KR294_000897"
     CDS             complement(16712..18139)
                     /gene="ascB"
                     /locus_tag="KR294_000897"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBH0239003.1"
                     /translation="MSFKNDFLWGGATAANQCEGGYNEDERGLANVDVCPTGKDRTAV
                     ITGKLKMFDFDDEHYYPAKTGIDMYHNYKEDIKLFAEMGFKVYRMSIAWSRIFPKGDE
                     ETPNEKGLQFYENIFKECKKYKIEPLVTITHFDCPMHLVKKYGAWRNRKMIGFYEKLC
                     NVIFRRYKGLVKYWLTFNEINMILHAPFMGAGICFEEGEDVEKIKYQAAHHELVASAI
                     ATKIAHEVDSNNLIGCMFAAGSVYPYSCNPNDVWEATKLDRENYFFVDVQSKGKYPNY
                     ALKYMEQKGITPEMEPGDIELLNKYTVDFISFSYYNSRCVRTDENADDMAEGNIFTSA
                     KNPYLSYSQWGWPIDPLGLRITLNHVYDRYEKPLFIVENGLGAKDIADENGYVEDDYR
                     IDYLREHIKAMHDAVSIDGVDLLGYTTWAPIDLVSAGTGEMEKRYGFIYVDRDNSGNG
                     SLRRMKKKSFEWYKKVIASNGEDLY"
     gene            complement(18200..20128)
                     /locus_tag="KR294_000898"
     CDS             complement(18200..20128)
                     /locus_tag="KR294_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBH0239004.1"
                     /translation="MGKYKQLAQEIVNNVGGKENISGLVHCITRLRFTLKDESIANDN
                     VLKNMEGIVTVMKSGGQYQVVIGNHVEAVYKDVVEIIGLDDSSTSSETKKSGNILDKG
                     IDIISGIFQPVLGIMAACGMLKGFNALFVAMGLYSDVSGGYMVINAAGDALFTFLPLF
                     LGYTSAKKFGLKPMLGLALGAAVCYPAIQGSSISAGADVMYTLFKGTMFASPVYIDFF
                     GLPIVSIDYTGTVVPIIFIVYFASRCEKLFNKCVPNLVKFFFVPMLTLLITVPVALIV
                     IGPIATFGSTLISQIVISIRDFSPLLAGAIVGFTWQILVIFGMHWGFIPVYINNVMTL
                     GYDNVMMPFFACTFASSAVVLAIFFKTKDKKLKEMAIPNFISGIFGVTEPAIYGILLP
                     LKKPFIISCIASGIGGAFYGFFNLRKFITGGMGIFELPAMIEPDGGMGNLIVALSGIA
                     ISMVVAFVLTMILYKDEKVEESKKVRNKGKEEIKEVKSTKLEREIVTSPIKGEVLKLS
                     DIEDAAFASGVLGQGVAIIPSDGKVVAPVDGVVTTLFPSLHAIGILSDTGVEVLIHIG
                     LNTIQLEGRGFEACIKQGDRITKGQTILNFDVYAIKELGYSTVTPIVITNSSQFLDVV
                     ETESKNIELEDNLITVLF"
     gene            complement(20273..21115)
                     /locus_tag="KR294_000899"
     CDS             complement(20273..21115)
                     /locus_tag="KR294_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBH0239005.1"
                     /translation="MIINKILNNNVVITLDDNDEEVIVMGKGIGYQKSKGNLIDKTKV
                     NKVFRISNKEISNKLQELLNNIPIEHMKLSSEIIEYAQIKLNKKLNESIYISLSDHTY
                     SAIQRMKEGINVKNAILWEIKRFYKEEFEIGMKALDIIENKTGIKLPEDEAGFIAFHI
                     VNAQLSEGHTLASDITKLIQEVLSIVRYHFRIEFHEESVFYYRFIMHLKFFAQRLLLD
                     SAHEGETDKELLSIIKSKYNKEFECVVKIKNFIKKQYNYILTDDELIYLTIHLAKVVK
                     DSNM"
     gene            complement(21462..22832)
                     /locus_tag="KR294_000900"
     CDS             complement(21462..22832)
                     /locus_tag="KR294_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBH0239006.1"
                     /translation="MKNKYEEVAQLIIDGLGGKDNIIDLTHCMTRLRFILKDEKKVNA
                     DKLKSIDKVVGVNSTSTQYQVIIGNEVGVVFNAIINKGINTTGDIKSDIKNKNKKNSI
                     LNNIIDTITGCMTPMIPALTASGMIKVILSLCTTFNWLSSNSSTYRVLDIIGDVAFYF
                     MPIILAINAAKKFNVNTSIAVIVVGVFLHPNFSAWVSSGDPISFIGVPIQDVIYAASV
                     IPALLTVWMMSYIEKFIDKLTPSMLKTILNPTLVLLISAPIALIVIGPIGNFLGEGLA
                     SIINLLQGRLGFIMVCLLAAAMPFIVMTGMHHALTPIFISAFATTGQESLILISQVCA
                     NLAQGGATLAVALRSKDSKMKQLASAAWISAIMGITEPALYGVTLKLKKPAMLASIGA
                     GIAGLFAGITHVTLYVPQNSIMAVLGLSGEKGISNIVNGLIVIFIALVAPFIMTYVFG
                     VEKNVK"
     gene            complement(22871..23542)
                     /gene="pgmB"
                     /locus_tag="KR294_000901"
     CDS             complement(22871..23542)
                     /gene="pgmB"
                     /locus_tag="KR294_000901"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HBH0239007.1"
                     /translation="MKAVLFDLDGVITDTAKYHFEAWHEIAKSLDIEIDETFNEKLKG
                     ISREESLDKILLSANKVDSYTKEEKLKVCEEKNNIYIKLINSLTYKDILPGINELIKE
                     LKKNNVKLGIASASKNAPRILESLGIKDEFDCIVNPSLLKRGKPYPDIFIEGSKILNL
                     KQYDCVGIEDSYSGIKAINAANMTSIGVGKKEVLGKCDHIVEDTSLLNYNTLLQAWSK
                     KINLD"
     gene            complement(23544..25934)
                     /locus_tag="KR294_000902"
     CDS             complement(23544..25934)
                     /locus_tag="KR294_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HBH0239008.1"
                     /translation="MSLIFTTKDQLIEQGFSKDTIKSNETLFTLANGHLGVRGNIEES
                     DFNNEYVDNMGTYVNGFYEESPITYGESAYGYAKQNQTICKLPNAHIVNFSIEGDCFD
                     LSKGITSEHSRILDLNEGILKRSFIWENSRGRKVKVSIERLVSQDIEELMMISYTITP
                     LNFNGKIKFKNKMENSMEKFNCEKVEDPRVASINKKQFKINVKKYNNKYFMNLVTERS
                     RLGLWCGFDSYITCGNITNETYNVSDECIEREIEVYAKKDERLNLEIVVGYSRVYSDL
                     NLNEERLKSLECLESLKCLESEAHLKSLELVLREACNIGFDKVKNIQRKKMNEFWTTS
                     DVEIEGDKTLQLGIKTNLFHIYQSVGRDGKTNISAKGLTGDGYEGHYFWDTEMYILPF
                     FIYTQPSIARALLDYRYSILDASRERARELGINKGCLYSWRTINGNECSAYYPAGTAQ
                     FHINADIAYGIRTYFEATNDEEFMMQNGLEILIETARFWVEFGDYIESKNNKFCINGV
                     TGPDEYTAIVNNNYYTNLMAKYNLIYAVQMVDKFKHNLFSNEVFRKVKLQEYEVKNWI
                     NAAQNMYLPYDEEKKISKQDDSFLEKSVWDFKNTPKEKYPLLLHYHPLTIYRYQVNKQ
                     ADTVLSALLFPDEFSLEQKKRDFEYYEKITTHDSSLSRSIFGMMASEIGNHEKAYNYF
                     MDTALMDINNLQKNTSDGIHAANMGGTWMSLVYGFAGMKIKNDKLSFEPRIPKHWKNI
                     KFNILFRDNLVSVNIEEYKSYYKLIKGRNITILHDNKEIKLSKNIIEVNNCFKGSN"
     gene            complement(25960..27408)
                     /locus_tag="KR294_000903"
     CDS             complement(25960..27408)
                     /locus_tag="KR294_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HBH0239009.1"
                     /translation="MKLGKDFLWGGAISANQSEGFYLDGGKGLSQFDKLPLNDKRLKD
                     VCLDEDNILNENNQYYPSHIGIKFCENYKEDIAMLAEIGFKCFRFSISWSRIFPTGEE
                     SEPNEKGLQLYDNIIKELKKYNIEPLITISHFDIPYSLVEKYSGWADRRVVNLYVKYA
                     EILMKRYKDDVKYWIPFNEMNMIMHIPYIGAGLTFIADENQLQKKYQAAHHQLLANAK
                     TIEIGRYINKEFKFGCMLAAGKTYPYTCKPEDVFATLEHERHNLFFSDVQVRGVYPSF
                     MNYYLKSNQIKLIIKEEDLSTLKDNTVDFVSFSYYSSACSSARAEGLEKSKANGPETI
                     KNPYLPKSNSVWQNDPVGLRITMNQLYERYQLPLFIVENGLGTQDIVNEDGKIIDDYR
                     IDYMKEHIKNMIIGVNEDGIELIGYLMWGCIDVTSVSEGKMTKRYGIIHVDSDDYGRG
                     SFKRTKKQSAFWYKKVIETDGEILFNDMETHA"
     gene            complement(27811..28698)
                     /locus_tag="KR294_000904"
     CDS             complement(27811..28698)
                     /locus_tag="KR294_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBH0239010.1"
                     /translation="MAIYLEMPKLIHEFPFRSLSNEGEVLTTPHWHKEIEILLITEGV
                     VNLFINDKPMQLKKGEIVIIKGGDIHYILPSPGSERLVFQFDISFFNDLILLNEEKES
                     LINLFSSIKKCSRDWSAKIRKSVFDILIDIYNEDLYKIEGYSYAIKGKMYNLIPILYR
                     QIPREIEENTVEYEINSKEILERLNNIFKYVEKNYKQPIKLEDVSYEVGFSVYYFTKF
                     FKKNTGKTFITFLNEYRLEKAKWILLNNNISIVDLVEEVGFGSTKTFYRVFKEKIGVS
                     PLEFKKRYNSLEKKGSVSK"
     gene            complement(28798..29247)
                     /locus_tag="KR294_000905"
     CDS             complement(28798..29247)
                     /locus_tag="KR294_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH0239011.1"
                     /translation="MEIREILTEESIILDLKSTTKEGIIQELVDKLYDTGSITLKSKF
                     IKALKHREKIGSTSIGYQMAMPHGKTKYVKKASIVIGKSKKGVDWPSIDGLPVKVIIM
                     FAMPQSGGNEDMILISKIAYILGGKNIGERLLNANTKKEILDIFYEV"
     gene            complement(29237..31144)
                     /locus_tag="KR294_000906"
     CDS             complement(29237..31144)
                     /locus_tag="KR294_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBH0239012.1"
                     /translation="MLVSRQIEFLKLILNENKYRPIKYFKDKLNVSDKTLQKDLKMIE
                     KYLETFNIKIDIKRGYGILIEDLAKKNIDLINSLNIQSKENKSLSVEQRRMEILKYLL
                     LNSNNITSINQLADKYYVSKTSIVNDFKYIEAWIKEYNLKLNKTLEGTKIIGKEVDIR
                     KSIAKMMDDLLDENYEQHDISELTRLDSATFSALINLFDIDSIIFVETIITELEYNLG
                     YTINQPYYINLITHILICLKRIEEGNQIESQEEREISVDNLDELVYKNVSTLIDKIEN
                     RYRVKITKDEIMYIYIFLVSSGFSSENNSSYNDESDRLSESEKVSSIMIENMSRFLNI
                     NLKNDDLLQKSLASHVRPMLNRLRYDIQIKNPLLGEIQERFSDVLGLCMMTINIMTEY
                     DNLKNISIDEVSYLATYFQAAIERNMSSKRVIVVCHTGYGTSQLLAARLKREFPEWTI
                     VDIVPMHQLSKRNLDDVDFVISTVNLDLKDKLHIVVSVLLMENDINNIKNALLSKPKK
                     SMNLDTNLLGMYLEDNIYFNFDVAQMESLIGVNLGSKYESISLGKDLNIYIHKQSKLN
                     KGIMNINNVTRTIDIYLEISNQSFLKNILMEISNLYRQKNYINYIIDCKSKEDIKILF
                     KNNLLEKTNGN"
     gene            complement(31412..33307)
                     /locus_tag="KR294_000907"
     CDS             complement(31412..33307)
                     /locus_tag="KR294_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH0239013.1"
                     /translation="MIGKILRSDCIVLDKQLQTKKDVINYMANHLYHGNYINNKEKFI
                     ADINKREKESSTNMGNLIAIPHAKSNVVNQPVMMYLRTDREITDNDGQKLRSFFMIAV
                     PESGSDEHLKIISKLATYLMEENFLKHLLSAETPYEILSIFNNKAAESGDFSNNQNKG
                     LIVGITGCPTGIAHTFMAKKALEEAGQELGYEVKIETHGAIGVENKLTKEDIKRAEYV
                     IIACDKEVQLSRFIGKKVLQKKVVDAKNVSLAKNLIINAENGMAKEIKPGGKTLEDSK
                     EMLQGSEKKGVYKHLMSGVSEMIPFVVIGGIGIAIAFMFGIFASDPTHETYNPIAGFF
                     GQLGGDSAFKLFIPILAGFIAKSIAGRQGFAPAMIAGFMAVIGGSGFIGGMVAGFATG
                     YIALGVMKITENLPDVLKGVNAVLICPLLIAFTSGAIMFFVVNTPASWLNEALQSWLQ
                     SMSGTNKVLLGAILAGMMASDMGGPINKTASAFGLAMFSSNIFEPSAALMVGGMVPPL
                     AISLAMLIFKNKFTKEERKSSLPTAIMGASFITEGAIPFAAADPLRMIPANIIGSCIG
                     GAICMSLDITLMAPHGGIFVIPFACSAPVAYIACILIGTVITALIIGVTKPTIRSENS
                     EVELLGA"
     gene            complement(33343..34221)
                     /locus_tag="KR294_000908"
     CDS             complement(33343..34221)
                     /locus_tag="KR294_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HBH0239014.1"
                     /translation="MLINMKEMLKVAQENQFAVPAFNIGSGQILKAVVQSANEKNAPV
                     ILAIHPNELSFLGDSFVASCIEEANKSKVPMVIHLDHGENKEQILRAIRCGFTSVMID
                     GSHLPYEENVAISREIVEIAKGLNVSVEGELGTIGTTGTSSEGGTDEIIYTDSKLAKD
                     FVEKTGVETLAIAIGTAHGIYPKGFKPELKLDLLKEIREVVDIPLVLHGGSSNPDEEI
                     AQAVKLGVCKINISSDVKSAYYKKCRELLEQNPSLYEPDTIYPPCIKSAREVIEFKMN
                     LFNAIDKLKCFYKNKN"
     gene            complement(34926..36359)
                     /locus_tag="KR294_000909"
     CDS             complement(34926..36359)
                     /locus_tag="KR294_000909"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003243232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBH0239015.1"
                     /translation="MKSNQEFLWGGAVAAHQVEGGYNKGGKGISIADVMTAGTHTISR
                     KITDGVIEGLNYPNHEAINFYENYKEDIRLFAEMGYKCFRTSIAWTRIFPKGDESTPN
                     EDGLKFYDDLFDELLKYNIEPVITLSHFEMPYHLVKNYGGWRNRKLIDFFVNFCEVVM
                     NRYKDKVKYWMTFNEINNQSITTNPIYAFTNSGIIYEEQEDKEEVMYQAVHYEFVASA
                     KVVKIGHEINPEFKIGCMVAAMPSYPYSCNPEDMIKFVESNREQLMFTDVHVRGHYPR
                     HTLKLWERKNYNLDITEEDKKILKEGIVDFIGCSYYLTTVVTADKTMKTTGNDSAGKA
                     DVVENPYLKISDWGWNIDPVGLRFYLNQLYDKYELPIFIVENGFGAEDVLKSDNTVDD
                     DYRIEYLASHIREMKNAIEIDGVDVIGYTVWGCIDPVSFTTGEMKKRYGFIYVDKNND
                     GSGTLKRYKKKSFDWYKNVIKFNGEIL"
     gene            complement(36382..38223)
                     /locus_tag="KR294_000910"
     CDS             complement(36382..38223)
                     /locus_tag="KR294_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBH0239016.1"
                     /translation="MKFERESEEIIKYVGGKENIISLVHCATRLRFKLKDTSKTNKEE
                     LLKMKDVLSVVNSGGQYQVVIGNKVTDYFETIIKKAVLQGQNTEEQGEKVSIVSKIFE
                     SISGAFSPLIPALAGAGMIKALLTILTTMKWMSDTSSTYAILSAAGNAVFYFLPIFLG
                     ITLAIKLSANPYVGGVIGAALLDPNFTALIGAKGGANFFGMPVTAIDYSFGVFPIFVA
                     IFIYYYVDKLLKKIILKDLQLFLVPMISLLVMVPLTVILFGPIATNVGDIISNIFMGL
                     FEFNRVIAGAAIGIAMPFLAVLGLHWGFTPITLQNLATMGGDPIEGAAVAAVFAQIGI
                     AIGLFMKVRKSKKNSELKVLAGSTAVTGILAGVTEPIIYGIILRYRRMIPVLAIAGGI
                     GGGICGVFGVTCNAYVFHNIFSMPVYTPFLGYILGIGTALVLGAVLSYFFGLSKEECE
                     EGNEEVAFDEDDGIEEILSPIEGLQIELSEVEDEVFASGTIGNGMAIIPSKGEVVSPV
                     NGTITTIFPTKHAIGITSDKGVEILIHVGLNTTMLDGKYYTTHMNAGDKVKKGDRIVS
                     FDKDKIEGEGYSIVTPIILTNTNDLADVIVKENKHIKIGTPVIKVVY"
     gene            complement(38349..39182)
                     /locus_tag="KR294_000911"
     CDS             complement(38349..39182)
                     /locus_tag="KR294_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBH0239017.1"
                     /translation="MVIKKVFNNNVVFARDNSGQEVILMGKGIGFNKFTKDLVEIDKI
                     EKKFIFNNEESLSELHSLLDRIPLKDVELVSEIIQMGREELGDNLNDSILITLSEHIS
                     YMLKRMDEGLVFQSPLQWEIRQIYPNEYNFSKKAVEYLRKKLDKNIPDSEIAFITIHF
                     ANAQLETKDMQETLLLTKIIDNVLDIIKYHYGIEINEYSFDYTRFISHLRCFIKRQLS
                     GENTNVDTSLLDIIKMKYKSDYNCAKKVKNFLEKTYKWKISENELLYLTLHLNRLSNI
                     K"
     gene            complement(40226..40438)
                     /locus_tag="KR294_000912"
     CDS             complement(40226..40438)
                     /locus_tag="KR294_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0239018.1"
                     /translation="MAILMKTKIKEYREKLLMTQNELAKLVGVRRETIVHLENGKYNP
                     SLKLAMDIAKVFDTTVENLFEFIEEE"
     gene            complement(40439..40855)
                     /locus_tag="KR294_000913"
     CDS             complement(40439..40855)
                     /locus_tag="KR294_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239019.1"
                     /translation="MSKSETGVRSKLILELLVITYFFIAVLATKYIFKGPSTASLPGL
                     SWLIVFGCYSIYNKKYNDLVDESSEFILSKVNKIAIKIMIYSIVIISIFFATPYTSNI
                     NISNLDTGIILIAVLFIQSLSKLVLYIYFDKRGICN"
     gene            complement(40925..41338)
                     /locus_tag="KR294_000914"
     CDS             complement(40925..41338)
                     /locus_tag="KR294_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239020.1"
                     /translation="MSKSELGVKANLVSELMMLSYFFIDLLLQKFIFKGEGIWFTFII
                     LLAFWVCNLMYNKKYNDLVDEASKLMLLKVDQIASKIMLYSMFVIAVLFSVNHTRALD
                     ISNLDIGIMLLAVLFIQSLSKLILYIYFDKKGICN"
     gene            complement(42172..42801)
                     /locus_tag="KR294_000915"
     CDS             complement(42172..42801)
                     /locus_tag="KR294_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HBH0239021.1"
                     /translation="MKNRKVYMYVFDTMSDWEVAYLTAELNTGRYFKKGLKPLKVITV
                     GIDKNPIITMGGLKVLPEITVDEFNMESKDLLILPGGNTWLSMNHEIILEKVKEALIQ
                     DSIVAAICGATLGLAKKGLLDVRNHTSNDLEFLKMVIPNYSGEKYYKTESVVSDENLV
                     TASGIAPLEFTFQVLKLLDVFESEALNSWLNLYKTHDSKYFFELMNCNK"
     gene            complement(42880..43842)
                     /locus_tag="KR294_000916"
     CDS             complement(42880..43842)
                     /locus_tag="KR294_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017561613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing protein"
                     /protein_id="HBH0239022.1"
                     /translation="MAKIDNMMSILWMLNSDKKITAKQIAEKLEINIRTVYRYIDVLS
                     ASGVPIISDTGHNGGYSLLNNFTKAPLFFDIEEQKSLLHAALFAKKEGYFLDEALDKS
                     ILKLKMYSNQNQEDILTNHLRALEVIKPIGKVSIESVLKKLENSILKELSVEINYHAG
                     RKAKSKYRIINPYGIVHWNNNWYVVAFCNMRNEVRSFRVDRISEIIETSNTFNRPTEF
                     SASEFFIKGIIPEIKDEQNIIQLVVEGSIDSLDSLSQHWFLGHYLKERTPNKIIFMLE
                     EEVICKYIPNILLPYRKTIQVIEPLSLRKKIIEDLLELIDYYQI"
     gene            complement(44604..48329)
                     /gene="cbpA"
                     /locus_tag="KR294_000917"
     CDS             complement(44604..48329)
                     /gene="cbpA"
                     /locus_tag="KR294_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding adhesin CbpA"
                     /protein_id="HBH0239023.1"
                     /translation="MQQKCKKKALSMILSISMGLGSVASFNASNTFADTIEESTNAGN
                     AEGDTNAGNAEGDTNAGNAEGDTNAGNAGGDANAGNAGGDANAGNAGGDANAGNAGGD
                     ANAGNAGGDANAGNAEEDSNAGNAEGDANAGNAEEDANAGNAEEDSNAGNAEEDMNAL
                     VVEEATAEDPTSVGDFKISGGEINVDFKFASGVLTILSGKQMTIQNNNPNTPTTHRIV
                     IPKDVKAELIFDGVNIKTASNSPFTLTPDKDGGAYAHVILQDGSENKLESGDVYYPGM
                     RAGKGTTLTIDDSVVNRDIEGEFIVPEGGKIPRDVTLENGDKLKKGDRLTLLDSNNRG
                     SLKVVGNYYSAGIGGGNTESGGNIIINGGAITAIGQESSRNTGYGAGIGGGGNGSGGD
                     ITINGGTITAKGAYHGAGIGGGYYTTTKNALSPSVVDPSTGSGYSGNITINGGLSYSY
                     GGAHGSAFGDGCVNPGTNRGYRILVTGGTILPYMTGVGDWIFDLSATTGDVIVTGGSL
                     KATTFKSLGGAVAYGDLEKKTKVFMNKISLKYLGQDKVSTTLVDDFKMLIDGKIYPYG
                     APSYTDDQGVLYLWFSDQFKGSEVSVNLVVIDKITGGNIKPDDFYVKDIGSGSQFLKQ
                     YEEFTIDDTPPYLIIKRYDGLPFEEDVEKLFLDWILKDGGIPIITPKGEKLTDKKFMT
                     ISSQRLNEETMEPDTNLGSDDLTKQVDAGKYQLSITSTQFSNVYPFNEAYWGHRAYYK
                     AEIIPADTETSLVVEESKAKTDVFKPTDTFTLNVTISPDKKEGPDCASPRGYVQFYIN
                     GKEYKDPVELKTHNKGSESHNYSTASIEWRPLDSNHHIFTTEQTITVKYIGDDINYIE
                     GSEDEKKLKLDMTNVDVDGDGIPDINIDTDGDGRPDINIDTSGDWKPDINIDTDNTGE
                     WKPSTEGGNGDGIWKPDKNIDTNGDGNPDTDYNRPAIDTDNDGVDDYWKPDKNVDTGS
                     GGYDTGNPNLNKPDPDNGGNSKPDPDNGGNSKPDSGNGGNSKPDSGNGGNSKPDSGNG
                     GNSKPDSGNGGNSKPDPDNGGNSKPDPDNGGNGKPDPDNGGNSKPDPDNGGNSKPDPD
                     NGGNSKPDIDTDGDGKPNINIDIDGDGKPDINIDTDGDGKPDINIDIDGDGKPDINID
                     IDGDGKPDINIDIDGDGKPDINIDTDGDGKPDINIDTDGNGKPDINIDTDESLDSNVG
                     QNVQTGDQSNIMLDLALMFISLFFLIKNLTNKYLRRK"
     gene            48598..49170
                     /locus_tag="KR294_000918"
     CDS             48598..49170
                     /locus_tag="KR294_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class B sortase"
                     /protein_id="HBH0239024.1"
                     /translation="MEKLVKILINIICIIALTFSSLSIYIKLSEYKKADEVYTELREN
                     TINNSKHQELYDKNNDYRFWLKINNVNINYPVVQGYNNDFYLTHDFYKNYLPLGSIFM
                     DYRNNFENDKSLIVYGHYMKNKTMFGQLENYTDEVFFKENNLVEINYKVQTYTYEIFS
                     VYTADLINRDYLSIHFNNNDEFKYSLNYIT"
     gene            complement(50170..51795)
                     /locus_tag="KR294_000919"
     CDS             complement(50170..51795)
                     /locus_tag="KR294_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012100074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HBH0239025.1"
                     /translation="MYNVIDLFAGAGGLSLGFEMTKKFNMVAFVEKNDNAAKTYLENH
                     PSVKRYCDIKRLDFQDILNSVDKIDVVIGGPPCQGFSNANRQKRKIINGNNELVKLYV
                     DAIDKLKPNVFVMENVKTISSNKHSFYLTKKDKNHIINNLKLNIYNKDSVLYDRTEYI
                     NELFNIISIEDIESYIISNIDLKNLKIIIKKKKDICDYLNKISNYKKVKSTIEKLETR
                     GKMPKWYLELINKVKNILENMLYNRNLSDEQIFYLNLFLDIQNLFLGIYELKSESVIF
                     ENTLDDNKIIAKMDTYIIIDYINASFEYLGYVLNGSALNSIDYGVPQNRERFVLIGAK
                     KDFLKNKKIETPKPIVGENYVTVRDAIGDLAEYEASKGSMDYCFEKNSNNIEKDFYRK
                     IILDSNKIYNHVCTDTRNIALKRFEYINQGNNFHSLPDELKGTYADPERTQNTIYKRL
                     VYDKPSDTVVNVRKSMWIHPIKNRAVSAREAARLQSFPDSYKFLGTKDSVYQQIGNAV
                     PPLLGRVVAEKILNLFNDEPNEYLRDVFEALDG"
     gene            52107..>53395
                     /locus_tag="KR294_000920"
     CDS             52107..>53395
                     /locus_tag="KR294_000920"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239026.1"
                     /translation="MLTTNIHYILDNDICEIYFNKQRLTNSKYYQDNINVLNYIINEK
                     NNNLIINYNDKYIYAIYLLNIAINSYLNNTLNPNNHILTKLDKGMPLLYKGQIVIFKN
                     INNTHITLGHKNKTDTTLIPIDSAYMLITYNGHLEVNSMGKTPASKTFQTKNVLSSLG
                     FSDLKNMTGVINDSTLIILPCKDDISDLVSNIKIKDINNTYKFTELFPCSYISSTGAE
                     TDYPGNHAKQIPLLKFTTNISSAFEIIKSDKSIKNVFIIGDYPIYKHINDFERILNRK
                     RIESVNIVTSNSNISNILDLPNIDNLNIYSWSKDVLLTYSQDFENTSTFQKLWLDKLI
                     NKNICTTSVDSNISDLIHQARKSLYYISKYDFDISIKNSLMMCSYSLLKILENTPFNL
                     DFLEETIKLLNLNIATPSAKLENIKYLISSTSPDLEL"
BASE COUNT        17607 a         9323 c         5606 g        20859 t
ORIGIN      
        1 aaattagtaa gactataata acttaaataa aattaaagtt aacaaagact attaaagtta
       61 gcaaatattc ctctacctaa ataattgctt tttataaaga gttatttatt ttaattgaat
      121 ttaattgaaa tacgatttta actagaacaa tagattaatg taatatttaa tataaaataa
      181 ttataataat tgaaaaggaa gtaatctatg atgaaaatag cagtcataac aaccgaattt
      241 ttaaaagagt ttgtagataa ttctataaaa aagttaaata ttaatgcaga aattgaaata
      301 tatatctata gagatttttc tcatgttgga gatttatatt tagaaataga agataggttt
      361 gatggatttg cagttagtgg ccccatcccc aaaaaagcta ttacaaaaaa ggctggaact
      421 attaaaaaac ctctagttga ttttggtact gacttacaaa gttactatga tatgtttcta
      481 aagcttatct ttaaatataa tacattagat ttttctagag cgtactttga cttaacagac
      541 tgggcagata atccaaaaga tatatcatat tatttatcaa atggcacatt tggagactta
      601 atggatagta ttgatgaaaa tgcatctaaa atgagtttat ctgacatagc aaaacttgaa
      661 aaaaagattg caaaaaaaca tattaatcta tggaatgaag ggaaaatcga tttttctact
      721 actcgtttta gtagtattgt tcctatgtta caaaatgcag gagtaaactt tcatttcata
      781 taccctgata tagatttatt aaaaaatact tttaataact taataaaaga tattcattta
      841 catagaatga agggaaatca accaagtgta atatatataa cagttaaaga tacaaattat
      901 gatgactcta ctctagacca agtttataaa atattaaata gtattaaaaa agataaatta
      961 accgatttta taattgaaaa aaatagtaat tcttttaaaa ttttcactaa atgtgaaacg
     1021 attaaatcat taactaaaaa ttttactgca tgttatataa aagaatctat tgaaaatagt
     1081 acaaatatta aagtatgtgt tggatatgga attggtaatg atataaagca agctatgtct
     1141 agtgccataa gtgctaataa ggaatctaaa ataaatcatt taaattacag tttcttagtc
     1201 aacgaaaatt atgagacaat aggaccttta ctgtgtgata agttacttac tgtttcaaat
     1261 aaagtaactc cacatataaa tacaattgcc aaaagttcta aattgtctac tcttactatt
     1321 caaaagatta tatctgttac tgaaattcta caaagagatg aagttactcc taaggaatta
     1381 tcttcatgtt taaatgtaac agttagaact gctaatagat ttctaagtag tctcttaaag
     1441 tctggaaacg ctactatatt atatgaaaaa caaaactcaa caaaaggtag acctgaaaga
     1501 gtatacaaat tatttatatc agaaaataaa tattaaaatc caaaatgcat aaaaatattt
     1561 tatcatctaa tattaagtaa aattatatat gactttctaa aaggtatatc tttgcatctt
     1621 tttaagatat accttttata atatttaata atattttatg ttattatcta ctaaaattat
     1681 tttctaacca ttttactgca caatgagcaa ataaagctga accataaact aatccctctt
     1741 cattaaaaat tgctttagga ttatgcatac caaaattata tccctgacta atacttccca
     1801 ttccaatcca taaaaatact cctggaaccc ttagtaaaat ctctgaaaaa tcttctgaac
     1861 ccattgcaga tggaaagtct attacatttt catttcctat aacttcttta acataagata
     1921 caatctcatc tcctacatcc aaatcattta taactgcagg agtccccatt ttaaattcca
     1981 ctttagcatt tcctccaaat gatttagcta ttcctgtaga tatttcaata attctatttt
     2041 ttaatttttc tctaacagat tggtcaaatg ttcttaaagt acctgacata gatgctttat
     2101 ttggtatagc atttggtacg cttcctgcat taaacatacc aatagttaaa actacaggct
     2161 ctttctgagg tttttctctt gaaagtatag tgtttaatgc tatttgtata tgtgacatta
     2221 tgtttattgg gtccactcca aattcagggc ttgctccatg agttgctttt ccttctactg
     2281 ttatttcaaa tatatctgca gatgccatag ctggaccacg tgaataagct acttgacctg
     2341 tgttaagaaa tttacccacc atactgtgaa atgccatagc tgcatcgacc tgaggatttt
     2401 ctaatatacc atcatcaatc attgattttg cacctctggt agtctcttca tctggttcaa
     2461 atacaaactt tactctacct ttaagtaagt gcttattatc cataagtatt ttagctgctc
     2521 ctaagagcat tgctgtgtga ttatcgtgtc cacaactatg agatgcatct ttattcttac
     2581 ttttaaaagg taaatccgtc tcctccataa taggaagtgc atccatatct gcccttaata
     2641 ataaggtctt tccaccattt ttactgtcta aaacagctac tattccatta ttagacgtca
     2701 atttcggaga atatcccatt ttttctaaag tactggtaac aaaggttact gttttcggta
     2761 gattgcaacc aatttcggga ttttcatgta aatatcttct ccatctaata atttcccctt
     2821 ctattgactg cgcttcttta aaaaaatttt tcatattcct tcctcctaat cagatagtca
     2881 gcaaaatctc actttctttt agtaatgaaa tgatgctgat ataaaaatta taattttata
     2941 tattaaattt catgtctttt taaggagttg gaatatcatc tggaatagga catttatatg
     3001 ttttaccatt catagattta tcaaattctt cttttgcctt tttagctatc tctggattat
     3061 ttaatatttt agctccaaac atagccataa tctttgatgc atatatcata cctttttctc
     3121 ctatagaact tcctgcacaa gatgtaaact gccagctatg acctggtgct cctagattcg
     3181 tacaccctgt aaaaaagtat gctgtcggaa ctatatgcat tacatctcca atatcagtag
     3241 agccataact attaaagttt gtaacatttc ctccaccata atatagatga gttccttctg
     3301 gcaaattata tttacttatc atagccttat attgttgtgg gctttgtcta tctaattcag
     3361 ctgcaaaatc caattcctct cgagtccaag gctcttgttt aatctcattc atacattctg
     3421 atacaagatt tgctaaaaca tgattgttta aagtattata acaccctcct aaaaactcta
     3481 cttcaacttc agtttcagtc atcattgcag ctccttttgc tacctttaca agtctttcat
     3541 atgtactttc tacagcttct ctacttaaag ctcttgtata ataccatact gatgctttat
     3601 caggaactat gttgggtgct actcctccat ctgtaattgt ataatgaatc cttacatcag
     3661 aagtaacatg ttctctcaaa taattagctc ccacattagt aagttccaca gcatctagtg
     3721 cacttcttcc attttgaggg tctgagcctg catgtgcagt ctttccctta aagtgaaact
     3781 ttacagagtt aacagctgtt gaagtaccaa ttgtagcttc actaatttta tttggatgaa
     3841 aatttatagc taagtctaac ccttcaaacg ctccacctct agccataaat cctttacctg
     3901 ttaattgttc ttctcctgga catgcataaa atactatagt cccacttaag ttattttcta
     3961 tcatctctct tttaagccct actactgccc ctacatgtgc tgtacataat aaattatgcc
     4021 cacatccatg accatatgca cccaattcaa atgcttcttg ttttgttgaa actttttgat
     4081 ttaaaccagg taatgcatca aattctccca taaaacctat aactggttta cctgaaccaa
     4141 aactagctct aatagccgtg gctaaacctc ctacacctac ttccacatca aatccttcac
     4201 ttcttagaaa gtttgctgta ttttcacatg ctttaaattc tttaaatgct ttttctggat
     4261 tttcccatat tttcttactt aaatcatcaa gtttgaatct ttttttatct atctcattta
     4321 tagatatact tcctatcatt ttctattcct cctataaatc tatttactat caaccaaata
     4381 taattggacc tattatacta gcaaatgcca ctgatgcaat ggttacagta acaaatcctc
     4441 ctataatcat ctttggtaat aaataatctg ttgccctttg tttttcttct tcagttcctt
     4501 ccatagcatc aataccttca ttggaaatta tctgtgttgc aggataagct agcatacaag
     4561 ttacaccaat tgcagctgac attcttggag aatatcccaa tagttttcct acaattgcag
     4621 taaatagtat tataaataca gagcctacaa caagtattcc tatagttgga ataatcatcc
     4681 caaacaatgc tgttggagtt accttagcaa gtcctccagg taacatcaac atacaaccaa
     4741 acattataat tccattagat tgagatttat ctaaaattcc tttttctaaa aaacctattc
     4801 gtgtaaaaat caaccctact aacaaacatg ctatgttggg atttaaataa tagtttgcag
     4861 gggtaaatcc tggtattaaa gtagccaatc ctacaaaatt accaatcata gcaacaaatg
     4921 aaagctttgc aagatatact aaagtagatg attttttacc taaatcttct ttaaaaattc
     4981 tcatacttgg aagtttaaaa ttactttttg actcatcttt caaaaaatcc ccgttatctc
     5041 ttttaaattt taattcttta tttatacaat atgtagttat cggaatgcca aagaactttt
     5101 gaaatgataa tactagaatt acaaatgcag caagttcagg tctatttgca gcttctgcaa
     5161 cagttgttac gataatacca gcaacagtag aacccgctat tggaggtgct gctattaaag
     5221 catactctct accaaataac atactaccca ctgttaaaca gccaacccct attcctacaa
     5281 tacctactaa tgcaattaca accgttttcc attcatgaca taagtcttca agatttataa
     5341 gtgttcctaa gttagttatt aataaagcta taccaaagtt gctcattgca gctaatatcc
     5401 ctgatgctcc tgtaatgtct tttggtaaaa tatttgtcca aaatcctagt aaaaatataa
     5461 tacatacaaa taacaatgtt gaaattgcac cttttgtttt cttagataaa aactcactaa
     5521 aagcataaat cattacacat acagtaaagc aagtaagtgg attccaaaaa ttttccattg
     5581 ttgtttcctc ctaaatataa taatttttta tcaataaaac aataattata aaatgtatat
     5641 tatgcagtta ttcttaacta catatggtat agcttgatat tttttgatga tattatatac
     5701 gtcctaaatt attcctaaaa tatctaaata aatataacta gagttaactc tctaaatatt
     5761 aactatagtt atcaacttac tagatttctt tttgattttt actttctaca taattttacg
     5821 agttagaatt gtacttcaac tattctctat attagtatac atgttggaag acttatattt
     5881 atttaaatat tagatataga atatattttt ataaacgtct taaattattc ttaaaatatc
     5941 taaaacgaaa taataatata cccattaaac caatattatc agaatatact tcactttaag
     6001 tcttctttat atagaaattt tatctattag tgcatcccct cccttgtaaa ttagactatt
     6061 tctaagcgaa tttagatatc ttattcctag agactattac taaaaacaaa aattatttat
     6121 tatattaaat caatgataag ccatacttta aaattctttc tatacaagta taatttatca
     6181 tataatgaca tctatacctt tatctttata gtagtcctaa attattctta aattgacaat
     6241 aaaaataatt tcactattta taaaaatact tgtttttata ttgtcaaact attcttaata
     6301 tagattataa ttttaaatct tttctttgtc aatatattct gacatttttc cagaaaattt
     6361 ataaagttat atagtgagta aatcatacta tttttatata atgagtaaat tatactatga
     6421 atatgtctaa atatttactt aagtataaaa ataaaaaatg tgtattctcc tttttatagt
     6481 aattttaatt gccattattt ttaagaagaa tacacacttt actttaaaga ccctatactc
     6541 tattttaaat gctttactag acactaatta acattagttc ctaacttcta tttatcttat
     6601 tcctacccta ctactatatc cgtagaaaaa tctaaaactt ctccattaga ttttattact
     6661 tctttgtacc aatcaaatga ttttttctta tatctcttaa aacttccttt gccttcatca
     6721 tctaagtcaa catagataaa tccatatctc ttactcatct gacctgtagt tgcactgact
     6781 aaatcaattg gtccccacat caaatatcca aaacattcaa cattatcttc ttcaattgca
     6841 gacttcattt gagatagatg cttacttaaa tattcaattc tataatcatc atttatagtt
     6901 ccatcttctt cgattttatc atatgcccct aaaccatttt ctgtaattaa gataggtaat
     6961 tgatactttc tgtaaatata gttcaaggta aatcttaaac ctatagggtc tattgcccac
     7021 ccccacttac tttgttccaa atatggattt tgaatcccac caaataaaga tttatcacct
     7081 gataaatttt cttttggagt agatacactt gaaaaataat aattaagtcc tataaaatct
     7141 aacttacctt ctttaaatgc ttttttgtct tcatcagtca cttcaatagt tatattattt
     7201 ttttcatatt cttttaattt atattgtgga aacttcccat tgcacattgc atcaatttga
     7261 taataatcac ggtcattatc taaaaatgca tttaacacat tactaggatt acaattgtat
     7321 ggataaattg gatttagtcc aaatacacat ccaattttat tgttgggatt gatttctcta
     7381 gccaactttg caacctttac acccgccaaa gtcatattat accctacatt tgccaatgtt
     7441 tgaaccttat tttctatttc actatactta atacctgcta tcatataagt aaaaatatcc
     7501 gagtgctctg tttgagggtc aatatggttc atctcattaa atgtaaccca gtactttacc
     7561 ttatcatcaa atcttcttat tacagtctca ctgtacttta aatacaaatc tataagtttt
     7621 ctgttattcc atgaaccata tttatgtact aaattcatag gtaattcaaa atgatatagt
     7681 gttacaatag gttctatatt attttctatt aatgtatcta tcagaccttc atagtattta
     7741 atccctaatt cattaggatt ttcatcatct ccatttggaa aaattcttga ccaatctata
     7801 gatattctta atgcactaaa tcccatttct ttaaataaag ctatatcttc tttatatcta
     7861 ttataaaaat ctattccatt atgagatgga taatctaatt tttcttctat tttatcagta
     7921 attactcttg gcgtttcata agagccctta gttacaaagt ccataattgc aggtcctttg
     7981 ttatcactat cccatgaacc ttcacattga tgggctgcaa tacttcctcc ccagaaaaat
     8041 gtatctttaa tattcatgaa ttttccctcc taaaatttat actattacag ttaataattc
     8101 ttctgattca tcatttgatg agattacatc taaataatcg ctagtatttg taactacagt
     8161 tattatagta gaatcaaagc cttcctctat aattttatca gattcaaata ctgctaaagc
     8221 atctcctttt ttaacccttt gattttgtgt tacaagactt tcaaagaatt ttccatctaa
     8281 gtttacagta tctatcccaa tatgaattaa tatttctaat ccttcatcag tcactatacc
     8341 atatgcatgt ttagttggaa atactatagt tatagttcca tctacaggag atataacagt
     8401 tgattttgat tcactaggta taactccaac ccctttacct aatgctccag aggaaaatgc
     8461 tttgtcatta acttccccaa gtgcaattac ctgacctttt gcaacatttc caatactaat
     8521 agttcttgaa ttgttctcgt tgattattag ttctaattct ttttcattat cacccttaac
     8581 ttcttctttt tcatctgaag gtattcctag taaataggaa gctgctgttg ctgctacaaa
     8641 tgatactact acacttatta tcataaatgt aaagttagat acctctcctc caacaagata
     8701 cgttggtaat gcagctaatc cccaaaccat tccatatgtt ttaacttgag ctaaacctgc
     8761 tattaaacca cctatacctc cacctatcat tactgctaca aatggtcttc tatatttcat
     8821 aaacacacca aacactgaag gttctgtaac tcccataagt gcactaaaac ttactgtacc
     8881 aaatagttgt ttttgttctt tattcctagt ttttaagaaa tatccaaaca ttgcaccaca
     8941 aactgcaata tcagatattg ttgcagcgcc cataaaaatt gggtcatacc ccaatgttgt
     9001 cacagaattt aaagatatag gcatagtaaa gtttgctgca ccaaaaacta ttaagagtgg
     9061 ttgtaaagct gcatacagtg caacaacact ccaattaccc aatgtatcaa ttaaaaacat
     9121 acatgcatag tttaatccat caccaatcca cataccaata ggtccaaata cagttaatgt
     9181 aactgataga gttattatta aagataacac tggaactaaa aaatagtgta atgctttagg
     9241 taatattttt ttcaaacctt caattataat tcccattgcc catactccta aaagtattgg
     9301 aataaaactg tttgcataag ttgtagcctg taaatttata ccaaataaac ttaatccttc
     9361 tacaccatct attgatgaag ataataacgt aactgctaac actactgcta tatagggatt
     9421 tacattaagt ctttttgctg atgctattgc aattaatact ggtaagaagt gaaatgtagc
     9481 acttcttaat gtatctaata tttgatatgt aggactgtca ctctgaagta tgccagacat
     9541 atttaaaagt gctaatatac ttgcaagtat accagctgca agtagtactt caattactga
     9601 agtcatagtc tctgagacta ccacaaagat ggaattaaat atacctttga tacctctaat
     9661 tccctttttt ctttcacttt ttatacttga ttcacttgaa cttaaaccta tcatagacat
     9721 aaactcgtta tatacatcta caacatgagt acctattata atttgataag caacatcatt
     9781 agaaactaca tcaattactc cttttaattt tttaatttct tctgtttgag cgatactcct
     9841 atcatttaaa gtaaatctta aacgagtaac acaatgcgct accgacttta tattttcttt
     9901 tccccctata agttttatta tattttcatt taaatcttta tatttcatct gattttgcct
     9961 ccagtctttg agtcacccta tttatatgca acattaaata agtttcttca cttatagata
    10021 tatcgacatt aaattgtgat tttatatatt ttcttatctt ttgaacactt ccaaatgact
    10081 ttggataaag ttgacttact tgtttatata aatctataga attatcttca tctattgaag
    10141 cttcatccga cataattctt tggataaagt actgtagatg agtagtaaat ctcatataat
    10201 ttgttgaagt ttcatctagc tctacattaa aatgatattt tattatagaa actatatctg
    10261 ctaaagttct caactctaca attgtactat catgagactc tttatttacc tccatattta
    10321 caaaatgaag tgctattgat actgcctcat catcaggaag attaattccc ttactatcac
    10381 caattaattt tagtgcatgc attccaattt caaaatgctt tggataaaat cttttaacat
    10441 tccataccaa aggacttttt ataaattgat tcttttcaca tcttttaagt aaaaactcta
    10501 aatggtctag taaggttaag cttagataat cacttgcctt tatatttaaa gctttctcac
    10561 catattcaat tatttcatta ataagaacta tattattgga gtctgagttt tgtagtagat
    10621 aactaaagtg ttctagcata tcgtatgaat ctagtatata tgttctctct atttcatttt
    10681 catttattac ttgtcccact ctttttttaa agccaattcc tttaacaaat acaataattt
    10741 catttttacc tctttttact aaggctacat tattatttaa aatctgaatt attttcatat
    10801 attcctcctt tcaataaaaa gaactcaagc atatatgtat agagtatccc tctatttttc
    10861 acatatatac ttgagttctg cctgctaatc agtaacatac tcaaaattat gactacgtcg
    10921 ccataattaa aattcttttt tgtttaattt catattctat atgttatact atccatataa
    10981 atctgtcaac ggtttcctag atattttttt attctataac tacaagctct gttatgcgat
    11041 tatctgacaa ggtttatata ctaaattgat actattttac cgtcactaat atttataata
    11101 ttgtctgaac cattatctat tttactatta tgaattatca tagtaatgct tttaaatata
    11161 atgaactgta tgttaacaaa taaattctta agatatatta acatataaag tcttaagttt
    11221 agttttattt aatcactatt aagatatatt aataggtaaa gcttcaaatt tagtttcatt
    11281 taaatgctag taagatatac taatatataa atacttaaat ttagttttat ttaaacacta
    11341 gtaagatata ctaatatata aatacttaaa tttaattttg tttaaacact agtaagatat
    11401 actaatatat aaatacttaa atttagtttt atttaaacgc tctagtgata tttttaaata
    11461 aattttaata aaaatcattc tattttgtca taaatcattt atctggctta tatttaagat
    11521 atattagtgg atactttaca ctttttaatt cctcattact tcttaaaagt ttattattat
    11581 tttccatatc ataaatttgt aacattactt tatttacata tagagcataa taattatcac
    11641 tataaaaata ttgatactca tatcgagggt catctttgta atacactttg tatagtattc
    11701 cttcgtaact tgccttcttg gctttttctt ttgtaatact ttttatatta tcttttgaaa
    11761 tatcttgttt taccatatac ttatcaatat atgtttcagc atctttccat ggtttaatgc
    11821 agtttttata tacaacaaac cctgttacac ttataatacc tataattaat actataaaaa
    11881 taactttata ttttttcata ttaatcctcc ttcatttatt atttaaaact cgatataatg
    11941 cactaaaaaa aggatgttat cttttttatt aaaatataac atccctcata tttagcatca
    12001 atatatatgc cccaactggt aggttaaaag accccactgt cagtactttg attaaattac
    12061 atgtatgtat atatattttt aacaaatcta ttatatgtca acttgtctac tattacatat
    12121 aatctgtaat attacatctg ctgctttttt tgagcctcct gcattataaa agctttttga
    12181 tagtttagtt gcattttctt tatattcatt gtcatttata acttgaaata ctgctttttt
    12241 aatactttct gacttatcct cttttaacat aattcctgct cccaaatgaa caactctctt
    12301 agctaccatt ctctgctccg aatgttgagg aaataatacc ataggtactc cataatataa
    12361 actttcatta acactattca tcccagaatg agtaacaaac acatcagttt tttgaagtat
    12421 agcaatctgt tcaacactat ttttgacctc aaaattattt ggtatatttc ctaaactttt
    12481 aatatcagta cttctaccaa cagacataat cacatcaaca tcagaatctt taaatgcact
    12541 tatacagttt ttataaaagc taacattttt attattaatt gtaccaagcg aaatatatat
    12601 tagctttctt tttctctctt taggttcaat aatcaacttt gatactgatg gacctacaaa
    12661 tgaatactta ctagagaagg tttctaccat tggttgaaat tcttttgatg tatatacaat
    12721 ggtatccgta tcattatcat tagaaactat agaaataaaa ttttttactt catacccttt
    12781 tctttgtaaa agctttattt ttttattaat gcgtcttaca ccaaaaatca tacgtataat
    12841 ttctataaag ttttgtttca tcaactttgc tgtatgttta ttaaatgcaa aagttgttgt
    12901 agagcataca tatggaatat taagtttttg tgcaaataac tttccccaaa aacttaatga
    12961 atctgataca atgcaatctg gattaaaatc tttaagttct ctacaaactt tttcatctaa
    13021 agaaatagta gtatctacta tcatctcaat taatccagga aaatccttac caattttttt
    13081 ctcatctcca gggagtaatt ctggaaggta tttatcacaa caaataaatt ttgctccagc
    13141 accttcaatt ttatctttaa attcattaaa agaataatac aatacctcat ttcctctatc
    13201 cactaattca cgaactactt caatagtagg attagtatga ccatatgcag gaatgctaaa
    13261 aaatactatt ttactcatat ttcatacctc cttttataat ttttttaaat cattcttctt
    13321 tacgtactac tcccacatga cctataaaat ttatcaaatc acgttgatga acaattccta
    13381 atcctctttc ctcatctcca agtaccaata atttatctcc tgcatttata ttaaatactt
    13441 ctcttgcttc ttttggaatg acaatctgac cacgttcacc aactacaact gctccaaaga
    13501 aaaactttcc tttaggaggt actataatac ctgttttttc ttctgaatga ttaactaagt
    13561 catctagttt gacattgtac aattttgcaa gtttaatgca actacatata tcaggaatag
    13621 attctccact ttcccatttt gctattgatt gtctagaaac attaagtttt tcagctaatt
    13681 cttcttgtgt atactggttg atttttctta gactttttaa attctcatta atcatatttt
    13741 tcatacctcc tatgtttata atattggatt tattatttaa attctatcaa ctaatcttaa
    13801 cattcatata tatatttata tacttttatt atataaattt attattcagg taacatattt
    13861 ccttaagtta tcgtaaacaa aaaaacaagc acaaatctac taactgttgt taaagtattt
    13921 aagttaaggt catttacatt atcaaatatt tctacacctt taaaataacc tttatattta
    13981 taatctttca taagcaaatt attatccctt ctcatataca agtccagttg atgtcttgtt
    14041 gctaaattta atggtaatca aattctttac caataagtat aaaaattact aatgtgttat
    14101 aattttctta actactaaat tttacataca tttgaataga atatatcaat aaattactat
    14161 aataaataaa aaatagttag ggagatatta ttatgatttt atattttagc ggaactggta
    14221 atagccgata tgtggctcgt aaaattgcac aagaattaaa tgatgaactg atatcactaa
    14281 atcaacttat aaaagaggaa aaaacagatg aattaatatc agcagataaa ccattcatat
    14341 ttgtatgtcc tacttatgca tggagattgc caatagtagt tacggatttt ataaaagaaa
    14401 caaaatttct aggaagcaac agagtttact ttgtaatgac ttgtggtgga gatacagcaa
    14461 aatccataaa ctatattcaa aaactatgta aatacaagga atggcaatta aaaggtatgg
    14521 cagaaattaa aatgccagag aattatatag ctttattttc tacaacagac aaagaaacat
    14581 caaaacaaat gattaaagaa gcagataaac aaatatatag gattatttct gatatacgca
    14641 atgaaaatga atttgaaact attactccta gtggcttagg aggtacaatt aaaagtggta
    14701 taataaatac agttttttat aagacaatta ttagtgccaa aggatttcat tatactgata
    14761 aatgcattgg ctgtggaaaa tgtgtagagc tatgtccttt aaataatatt aatttaaaaa
    14821 acaaaaaacc agtttggaaa aataactgta ctcattgtat ggcatgtatt tgtggttgcc
    14881 ccactgaagc tattgagtat aaaaataaaa ctcaaaacag agaaagatac tatttagaat
    14941 aatatattct taatatttaa accattataa aatgaactat acccattgtt ttatacagtt
    15001 ttacatattt taaccgtctc ctaaaatggg tatagttcaa aagatagtgt ctcaaagtga
    15061 attttttagt tcctaaatca atctttttgt attaaatcaa gtataattta atcacctttt
    15121 cttatatcat tttcactaat atgttgtatt ccaacaaata taagatttat tagctctgtt
    15181 agtgacttcc attgtgattt ttttgaatca agataataat aatttttcgt tccttctcta
    15241 cgcaaattaa caatctctgc ttcttttaat atcttaagat gatgagatac agcaggacga
    15301 gaaagatgtg ttttttttgt gatttctccc actcgtatac cattaaaatc actctctaaa
    15361 agagcaatta aaatcaattg tctagtctca tcacccatag cagagatagc tttgcgacat
    15421 tctttaaatt tagacgttat ttcttgcatt ctttgttgac attctttttc cataaaatcc
    15481 accctctctt ataagtatct aacagttgct acttctttct gtgcagtacg tctatattta
    15541 acatctgggt atccaattac taatgttgta agaacatgat tactacgttt tagacctaaa
    15601 agctttttta attttggcga attatttgct acatctgaaa aatatccact aaataaaaca
    15661 cctagaccat aagactctgc cattaatgcc atatttgatg ctgcaagtga accactaatc
    15721 ttatcttttg taattatcat tattgcaata ggagcatgct taaagaaaaa gttatcgtca
    15781 atctcaactt cttttgaata tttaatagct atatttgcaa taggttttat ttttctaaaa
    15841 aatttcactg cttcgttttc ataaattgac tttttattgt ctaaaacaat atatgataca
    15901 tcttgtgaat ttttagcact aggggtatac ctacctgcct caataatttg ctttataatt
    15961 tctgaagaaa cttctttatc tttaaattta cgtatacttc ttctagattt aattgccatt
    16021 agtaattcat ctgaatctag ctttggctta tttgtaagtt ctataggagg ttcatcaaat
    16081 cctgtcaagg taatagcttt tgtgggacat attgctgcac aatgtccaca cattagacaa
    16141 tcttgttttt taattactga ctttttattt tctataatta tattgtttac tggacaatca
    16201 tttttacaaa gcccacatcc aatgcaaagt tctttgtcaa cttctattat atgttggtat
    16261 ttcatattca ttcatctacc tttcgtttat tagtttaaac tattataaca cgtagacatt
    16321 ttttatattc attggtaaag aatttgatta ccattaaatt tttaatttct ctattaaata
    16381 aatttttcat agaattttaa aatatcatag tttatacata ataaaaaaga caagcttaaa
    16441 acctaagctt gcctttttca tcttttatta caaagtaaat tgcacttact tcccatactt
    16501 cttaacaatt ttattttcta aaattttatt tgtgaatcat actattgcat caatacaatg
    16561 taaaataatt ctatattgat tttctatagt taaaaaagtt aaaaattata cttattatta
    16621 atttttatac tcttcttatt taatacaaag ttcttattta acatagattt cttgtctaat
    16681 atagatttct tatttaacat agatttcttg tctaatataa atcttcacca tttgaagcaa
    16741 ttactttctt ataccattca aaacttttct ttttcattct tcttagactt ccattaccac
    16801 tattgtctct atctacatat ataaatccat aacgcttttc catttcacct gtaccagcac
    16861 ttactaaatc aataggtgcc catgtagtat aacctaataa atcgacccca tctatagaaa
    16921 ctgcatcatg catagctttt atatgttctc ttagataatc aattctgtaa tcatcttcta
    16981 cataaccatt ttcatcagct atatctttag cacctaatcc attttctaca ataaatagtg
    17041 gcttttcata tctatcatat acatgattta gtgtaattct caaacctaat gggtcaattg
    17101 gccatcccca ttgactgtat gaaagatatg gatttttagc agatgtaaat atgtttcctt
    17161 cagccatatc atctgcattt tcatcggttc taacacaacg gctattgtaa tatgaaaatg
    17221 aaataaaatc tactgtatat ttattcaata attcaatatc accaggttcc atttctggtg
    17281 taataccttt ttgctccata tactttaacg catagttagg atatttacct ttagattgta
    17341 catccacaaa gaagtaattt tctctatcta actttgtagc ttcccataca tcattaggat
    17401 tacaactata aggatataca cttccagctg caaacataca tccaattaag ttatttgaat
    17461 caacttcatg tgctatttta gttgcaattg cactagctac aagctcatga tgggcagctt
    17521 gatattttat cttttcaaca tcttcacctt cttcaaagca aataccagca cccataaatg
    17581 gagcatgtaa aatcatattt atttcattga aagttagcca gtacttcact aatcctttat
    17641 atcttctaaa gataacattg cataatttct catagaaacc tatcattttt cgattacgcc
    17701 atgcaccata ctttttaact aaatgcattg gacaatcaaa gtgtgtaata gtgactaaag
    17761 gctctatttt atatttttta cactccttaa atatattttc ataaaattga agtccctttt
    17821 catttggtgt ttcttcatca ccttttggaa atattcgact ccatgcaatg ctcattctat
    17881 atactttaaa tcccatttca gcaaataact ttatatcttc tttataatta tgatacatat
    17941 caataccagt tttagctgga taataatgct catcatcaaa atcaaacatt tttagtttcc
    18001 ctgtaataac tgctgttcta tcttttcctg ttggacatac atctacattt gccaatcctc
    18061 tttcgtcttc attgtatcca ccttcacatt gattggccgc agtagctcct ccccataaaa
    18121 aatcattctt aaaactcata gtcaaagcct cctaaaatta taaccaaagc actagattat
    18181 gctaatacct caatctttac taaaataaga ctgtaattag attgtcttct aattcaatat
    18241 ttttactttc tgtttctact acatctaaaa attgtgatga atttgtaata acaattggag
    18301 ttacagtact ataccccaac tcttttattg cataaacatc aaagtttaat atagtttgac
    18361 cttttgtaat tctatcacct tgttttatac atgcctcaaa acctcttccc tctaattgaa
    18421 tagtatttaa tccaatatga ataagcactt caacacctgt atcagaaaga atccctatag
    18481 catgtagact aggaaataag gttgtaacta ccccatctac tggagcaact acttttccat
    18541 cactaggtat tattgccacc ccttgaccta gtacaccaga tgcaaatgct gcatcctcta
    18601 tatcacttaa ttttaatact tcacctttta taggacttgt tactatttct ctttctaatt
    18661 tagtagactt gacttctttt atttcttctt tacccttatt tcttactttt ttagactctt
    18721 ctactttctc atctttatat aaaatcatag ttaatacaaa agctacgacc attgatatag
    18781 ctataccaga aagagctact attaagttac ccattccccc atctggttca atcattgctg
    18841 gaagttcaaa tattcccatt cctccagtta taaattttct aagattaaag aatccataga
    18901 aagcgcctcc aataccacta gcaatacaac ttattataaa tggtttcttt aaaggcaata
    18961 atattccata aattgctggc tctgtaactc caaatatacc agatataaag tttggtattg
    19021 ccatctcttt tagtttttta tctttagtct tgaaaaatat tgccaacaca actgccgaac
    19081 ttgcaaatgt acaggcaaag aatggcatca taacattatc atatcctaaa gtcataacat
    19141 tgtttatata tacaggaata aatccccagt gcataccaaa aataacaaga atttgccaag
    19201 taaatcctac tatagcacct gccaatagtg gactaaaatc tcttattgaa attacaattt
    19261 gtgaaataag tgtagaacca aatgttgcta tagggcctat aactataagt gcaacaggca
    19321 ctgttattaa taatgtaagc attggcacaa agaaaaactt aactaaattt ggaacacact
    19381 tattaaataa tttttcacac ctagaagcaa aatacactat aaatataatt ggtacgactg
    19441 ttccagtata atcaattgat acaattggta gtccaaagaa atcaatatat actggtgatg
    19501 caaacattgt tcctttaaat aaagtgtaca tcacatctgc tcctgctgat atactgctac
    19561 cttgtatagc aggataacat actgcagctc ctagtgctaa tcccaacatt ggttttaatc
    19621 caaacttctt agctgaagta tatcctaaga acaaaggaag gaatgtaaat aatgcatctc
    19681 ctgctgcatt tattaccata taaccaccag atacatcact atataatccc attgctacaa
    19741 ataatgcatt aaatcctttc aacataccac aagctgccat tattcctaac actggctgaa
    19801 aaattcctga tattatatct atacctttat ctagtatatt acctgatttt ttagtttctg
    19861 aacttgtact tgaatcatct aaaccaatta tttcaactac atctttatag acagcttcaa
    19921 catgatttcc tataactact tgatattgtc ctccactttt cattacagta acaatacctt
    19981 ccatgttttt taatacattg tcatttgcta tactttcatc ttttaaagta aaacgtaatc
    20041 ttgtaataca gtgtactaac ccactaatat tttcttttcc accaacattg tttactatct
    20101 cttgtgctaa ttgtttgtat tttcccattt ttctcctcca tatttcgttt aaattaattt
    20161 tttgaaattt gaaggtttgg ccaactcaat gttaccatcc aaccataagt ataattttgt
    20221 tagtatcact cctttcaatc attcttaata tactactgaa aaattatttc acttacatat
    20281 ttgagtcttt aactacttta gctaaatgta ttgttaaata tataagctca tcatctgtta
    20341 atatgtagtt atattgtttt ttaatgaaat ttttaatttt aactacacat tcaaactctt
    20401 tattatattt agatttaata atgcttagta attctttgtc tgtctcacct tcatgtgcac
    20461 tatctaaaag caatctttgc gcaaaaaact ttaaatgcat tataaatcta taataaaaca
    20521 ctgattcttc atgaaattct atcctaaaat gatacctaac tatgctaagt acttcttgta
    20581 ttaacttcgt aatatcagat gccaaagtat gaccttcact taactgagca ttcactatat
    20641 gaaaggctat aaatccagcc tcatcttctg gtaattttat acctgttttg ttttcaataa
    20701 tatctagtgc tttcattcca atttcaaact cttctttata aaatctttta atttcccaaa
    20761 ggattgcatt ttttacattt attccttctt tcatcctttg aattgcagaa tatgtatggt
    20821 cacttaagga tatgtaaata ctttcattta gcttcttgtt taactttatt tgtgcgtatt
    20881 ctataatttc acttgataat ttcatgtgtt ctataggaat attattgagt aattcttgta
    20941 gtttgtttga tatttcttta tttgatattc taaatacttt atttacttta gttttatcta
    21001 ttagattgcc ttttgatttt tgataaccaa ttcctttacc cataacgata acttcttcat
    21061 cattatcatc taatgtgatt acaacattat tgtttaatat cttattaatt atcatgatta
    21121 tcctcctttt aagcataaaa aaagcttatc cataataatg ggcatactcc ttcctaggat
    21181 actgctatta ttaatgaata agcttagctt gtacttaaac aattactacc taattccaat
    21241 taatatgata aaacatcaga catattttgt caacttttta tttccatata cttcatcaat
    21301 cttttatgtt gctttttgtc agttctaata attattctta ttaatattaa cttatttctt
    21361 tgcatcaata taaatacaaa acaagttata gtcaataata ataaaaattc tattaatgta
    21421 aatagttaat attatacttc ctctactaca ttatctgtac tttatttaac atttttttca
    21481 actccaaaaa catatgtcat aataaatgga gcaaccaatg ctataaatat aactataagt
    21541 ccatttacta tatttgaaat ccccttttcc cctgataatc caagtactgc cattatacta
    21601 ttttgtggaa catataaagt cacatgagta attcctgcaa ataaccctgc gattcctgct
    21661 cctatagatg ctaacatagc aggtttttta agtttcaatg taactccata aagagctggt
    21721 tcagttatac ccatgatagc tgatatccat gcagctgatg ctaactgttt catcttacta
    21781 tctttgcttc ttaatgctac agctaatgtt gcgccacctt gcgctaaatt agcacaaact
    21841 tgagatatta atattagcga ttcttgtcct gtagttgcaa atgctgatat gaatatagga
    21901 gtcaatgcat gatgcatccc tgtcataacg ataaatggca ttgcagctgc taataaacaa
    21961 accattataa atcctaacct tccttgtagt aaatttatta tactagctaa tccctctcct
    22021 aagaaatttc ctattggtcc aattactatt aatgctattg gcgcacttat taataatact
    22081 aaagttggat ttaaaattgt ttttaacatg ctaggtgtta atttatcaat gaatttttct
    22141 atatatgaca tcatccatac tgttaaaagt gcagggataa cagatgctgc atatataaca
    22201 tcttgaattg gtactcctat aaatgatata gggtccccac ttgataccca tgcagagaaa
    22261 tttggatgta aaaacacacc tactactata actgctattg atgtattaac attaaatttt
    22321 ttagctgcat ttattgcaag tattataggc ataaagtaaa atgctacatc tcctattata
    22381 tctaatactc tatatgtact tgaatttgat gatagccaat taaaagtggt gcaaagagat
    22441 aatataactt ttatcatccc agatgctgta agggctggta tcataggtgt catacaacca
    22501 gttattgtat ctattatatt atttaaaata ctattttttt tatttttatt ttttatatcg
    22561 cttttaatat ctcctgtggt atttatcccc ttatttatta ttgcattaaa tacaacacct
    22621 acctcattac ctattatgac ctgatattga gttgaagttg agtttactcc aactacctta
    22681 tctatagatt ttaatttatc tgcattgact ttcttttcat cttttaagat gaaccttaat
    22741 cgtgtcatac aatgagttaa gtcaattata ttatcctttc ctccaagtcc atcaattatc
    22801 aattgagcta cttcttcata tttattcttc ataccttatc ctctctttta aaataatttt
    22861 taatataatt ttaatccaaa ttaatctttt tactccaagc ttgtaatagt gtattgtaat
    22921 ttaataagct agtatcttct acaatatggt cacattttcc tagtacttct tttttcccca
    22981 caccaattga tgtcatatta gcagcattta tagctttaat acctgaataa gaatcttcta
    23041 ttcctacaca atcatattgt tttaaattta gaatcttgct cccttcaata aaaatatcag
    23101 gatatggttt tccccttttt aataaagatg gatttactat acaatcaaat tcatctttta
    23161 ttcccaaaga ttctaatatc ctaggtgcat tcttactagc agatgctatt cccaatttca
    23221 cattattttt tttaagttct tttataagct catttatccc tggtaatata tctttatatg
    23281 ttaatgagtt tattaacttt atataaatgt tatttttttc ttcacacacc tttaactttt
    23341 cctctttagt ataactatct actttattag cagataacaa tattttatct aatgattctt
    23401 ccctgcttat gccttttaat ttttcattaa aagtttcatc tatttctata tctagcgatt
    23461 ttgctatctc atgccaagct tcaaaatgat acttagcagt atctgttata actccatcaa
    23521 gatcaaataa gactgctttc atattaatta ctccctttaa aacaattatt aacttctatt
    23581 atgttctttg ataattttat ttctttatta tcatgtaata tggttatatt tctacctttg
    23641 attaacttat aataagattt atattcttct atatttacag aaactaaatt atctctaaat
    23701 aatatattaa atttaatatt tttccagtgt ttaggtatcc ttggttcaaa acttaattta
    23761 tcatttttta ttttcattcc tgcaaatcca tatactaaac tcatccatgt tccacccata
    23821 ttagcagcat gtattccatc acttgtattt ttttgtaggt tattaatatc cattaatgct
    23881 gtgtccataa aatagttata agctttttca tgatttccaa tttcacttgc catcattcca
    23941 aatattgacc ttgacaaaga tgaatcatga gtagttattt tttcatagta ttcaaaatct
    24001 ctcttctttt gttctaagct aaactcatca gggaaaagca acgctgaaag tacagtatct
    24061 gcttgtttat ttacttgata tctatatatt gttaatggat gataatgaag aagtaatgga
    24121 tatttttctt ttggtgtatt tttaaaatcc catactgatt tttctaaaaa tgaatcgtct
    24181 tgtttgctta ttttcttctc ttcatcatat ggtaaataca tattttgagc ggcatttatc
    24241 cagtttttca cttcatattc ttgtaattta acttttctaa atacttcatt tgaaaataaa
    24301 ttatgcttaa atttatctac catctgtact gcatatatta aattatactt agccattaaa
    24361 ttagtgtagt aattattgtt tactattgct gtatattcat ctggtcctgt tactccattt
    24421 atacagaatt tattattttt tgattctata taatctccaa attcaaccca aaatcttgct
    24481 gtttctataa gaatttctaa gccattttgc atcataaatt cttcatcatt agttgcttca
    24541 aaatacgttc taataccata agctatatct gcatttatat gaaactgtgc tgttcctgct
    24601 ggataatatg cactgcattc attaccattt atagttctcc atgaatataa gcaaccttta
    24661 tttattccaa gttctctagc tctttctctt gatgcatcta agattgagta tctataatct
    24721 aataaagctc tggcaatgga tggttgagta tatataaaaa atggtaatat atacatttct
    24781 gtatcccaga aataatgccc ctcatagcca tcacctgtaa gaccttttgc tgatatatta
    24841 gtctttccat ctcttcctac tgattgataa atatgaaata aattggtttt tatccccagt
    24901 tgaagagttt tatcgccttc aatctctaca tcagaggttg tccaaaactc attcattttc
    24961 tttctctgaa tatttttgac tttatcaaat ccaatattac atgcttctct taaaaccaat
    25021 tctaatgatt ttaaatgtgc ttctgattct aaacatttta acgactccag acattctaat
    25081 gattttaaac gttcttcatt tagatttaaa tcagaatata ctctactata gcctacaaca
    25141 atttctaaat ttaacctttc atcttttttg gcatagactt ctatttctcg ctcaatacat
    25201 tcatctgaaa cattataggt ctcatttgta atatttccac aagtaatata tgaatcaaac
    25261 ccacaccata accctaatct acttctttct gtaactaaat tcataaaata cttattgtta
    25321 tattttttta cattaatttt aaattgcttc ttatttatag atgccactct tgggtcctct
    25381 actttttcac aattaaactt ctccatacta ttttccattt tatttttaaa ttttattttt
    25441 ccattaaaat tcaatggtgt tattgtatat gaaatcatca ttaattcttc tatatcttgt
    25501 gatactaatc tttctataga tactttaact tttctaccac gagagttttc ccatataaat
    25561 gaacgtttaa gaatcccttc atttaaatct agtatcctag aatgttcact tgtaatacct
    25621 tttgataaat caaagcaatc tccttcaata gagaaattta ctatatgagc attaggtaac
    25681 ttacagatag tctgattttg ttttgcatag ccataagcgc tttctccata tgtaattgga
    25741 gattcttcat aaaatccatt tacatatgta cccatattat ctacatactc attattaaaa
    25801 tcagactctt caatattccc tctaactcct aaatgtccat tagctagtgt aaacagcgtt
    25861 tcattggatt ttattgtatc cttactaaac ccttgctcta taagttggtc cttagtagta
    25921 aatattaaac tcataataac actcctttct taaaatgaat tatgcatgag tttccatgtc
    25981 attaaataaa atttctccat ctgtttctat tactttttta taccaaaaag cactttgttt
    26041 tttagttctt ttaaatgagc ctcttccata gtcatcagaa tcaacatgaa ttatgccata
    26101 tcgttttgtc atctttcctt cacttacact ggttacatct atacatcccc acataagata
    26161 tcctataagc tctattccat cttcatttac tccaataatc atatttttaa tatgttcttt
    26221 catgtaatct atacgataat catcaattat ttttccatct tcatttacaa tatcttgagt
    26281 acccagtcca ttttctacta taaataaagg taactgatac ctttcatata actgattcat
    26341 agttattctt aaccctacag ggtcgttttg ccatacacta tttgattttg gaagatatgg
    26401 attttttatg gtttctggtc cgtttgcctt tgatttttct aaaccttcag ctctagctga
    26461 actacaagca ctagaataat agctaaaaga tacaaaatct acagtattat ccttaagtgt
    26521 tgataaatct tcctctttta ttattaattt tatttgattt gattttaaat aataattcat
    26581 aaagcttgga tacacacccc taacttgaac atcagaaaaa aacaaattat gcctttcatg
    26641 ctctaaagtt gcaaatacat cttctggttt acatgtgtat ggatatgttt ttccagcagc
    26701 taacatacac ccaaacttaa attctttatt tatatacctt cctatttcta tagtttttgc
    26761 attagctaat aattgatggt gtgctgcttg atattttttc tgaagttgat tttcatcagc
    26821 tataaaagtt aacccagcac ctatatatgg aatatgcatt atcatattca tttcgttaaa
    26881 aggaatccag tatttgacat catctttata tcttttcatc aaaatttcag catattttac
    26941 atataaatta accactcttc tatcagccca cccagaatat ttttcaacta gagaataagg
    27001 tatatcaaag tggcttatcg ttattaatgg ctctatatta tattttttta attcttttat
    27061 tatattatca taaagttgta atcccttttc atttggttca ctttcttctc ctgttgggaa
    27121 tattcttgac caagatatag aaaatctaaa acatttaaaa cctatttctg ctaacattgc
    27181 tatatcttct ttgtaatttt cacaaaattt aatccctata tgacttggat agtattgatt
    27241 attttcattt aaaatattat cctcatctaa acatacatct tttaatctct tatcatttaa
    27301 tgggagttta tcaaactgag ataaaccttt tcctccatct aaataaaatc cttcactttg
    27361 attggctgaa attgcccctc cccataaaaa atctttccct aatttcatgc atctacctct
    27421 ttcacaatat aaagttttat aatttctatc tcatatttag ttataagatt tttttcatac
    27481 tatacctttt aaataattca atttaaaaat ccaattatat tttttactca ctataattaa
    27541 tattgtctat tttcaatact ttcatattaa atatcaatat tagatatcta tgtatataat
    27601 tatatatata gcaaatacat ttttatatcc tcattattgt tatcttattc tcatatattg
    27661 ctgtatattt atatataaaa ggatttattt cgaaatagag gttgtattga gaactaaaat
    27721 ttagacttta taaatgaatg gaattttcat tgttgaaata ctgaaaatat atttgatttc
    27781 atataaaaga aagtgcctca tgaactaagt tcattttgag acactccctt ttttttccaa
    27841 gctattatat ctttttttaa attctaatgg agagactcca attttttctt taaatactct
    27901 gtaaaaagtt tttgtacttc caaaaccaac ttcttcaacc aaatctacaa tggatatatt
    27961 gttattaagt aatatccact ttgctttttc taatctatat tcatttaaaa aagttataaa
    28021 tgtttttcct gtattttttt tgaaaaattt agtaaaataa tatacactaa atcctacttc
    28081 ataagacaca tcttctaatt ttataggttg tttataattt ttttctacat atttgaatat
    28141 attgttcaat ctctctaata tctctttaga gtttatttca tattctactg tattttcttc
    28201 aatttctcta ggaatctgtc tatataatat aggaattaaa ttatacattt taccttttat
    28261 tgcataacta tatccttcta ttttgtatag gtcttcattg tagatatcta tcaatatatc
    28321 gaaaactgac tttcttattt ttgctgacca atctctacta cattttttta tactactgaa
    28381 taaattaatt aagctttctt tttcctcatt taataaaatt aaatcattaa aaaaagatat
    28441 atcaaattga aatactaatc tttcacttcc cggtgatggc agtatataat gaatatctcc
    28501 tccttttatt atcactatct cgcctttttt taattgcata ggcttgtcat ttataaatag
    28561 atttactaca ccttctgtta taagtaatat ttctatttcc ttatgccagt gtggtgttgt
    28621 taatacttct ccttcatttg atagactacg aaaaggaaat tcatgtatta atttaggcat
    28681 ttctaaatat attgccatat atatcctctc ctctctagtg tctaaaaatt aatttatact
    28741 atttaaaaga atacacattt tattttaaaa acctcaaatt tataatttat acaataccta
    28801 cacttcataa aatatatcta atatttcttt ttttgtattt gcatttaaaa gtctttcacc
    28861 tatattttta ccacctaaaa tgtaagctat tttagatatt aatatcatat cttcattgcc
    28921 tccagattgt ggcatagcaa acataattat tacctttaca ggtaagccat ctatacttgg
    28981 ccaatctaca ccttttttag atttacctat tactatggat gccttcttta catattttgt
    29041 ttttccatgt ggcatggcca tttgataacc tatgctagta gagcctattt tttctctatg
    29101 ttttaatgcc tttataaact tactttttaa agttatactt cctgtatcgt ataatttatc
    29161 tactaattcc tgtattatgc cttcttttgt agttgatttc aaatctaaaa taatgctttc
    29221 ttctgttaat atttctctaa tttccatttg ttttctccaa tagattattc ttaaataata
    29281 ttttaatatc ctctttgctc ttgcaatcta ttatatagtt tatatagttc ttttgcctat
    29341 ataaatttga tatttccatt aaaatattct ttaaaaaact ttgattacta atttctaaat
    29401 aaatatcaat cgttctagta acattattga tattcattat ccctttattt aatttacttt
    29461 gcttatgtat atatatattt aaatcttttc ctaatgaaat agattcatat ttactcccta
    29521 aattcacacc tattaaactt tccatctgag ctacatcaaa attaaaatat atattatctt
    29581 ctaaatacat tcctaataag tttgtatcta agttcatact ttttttaggt ttagaaagta
    29641 aagcattttt tatattatta atatcatttt ccattaatag tactgataca actatatgta
    29701 atttatcttt caaatctaag tttacagtag atattacaaa gtctacatca tctaaatttc
    29761 gcttactcaa ctgatgcata ggaactatat caactatagt ccattcagga aattctcttt
    29821 ttaatctggc tgcaaggagc tgagatgttc catatcctgt atgacaaact actattactc
    29881 ttttactact catatttctt tctattgccg cttgaaaata tgtggcaaga tacgaaactt
    29941 catctatact aatattcttc agattatcat actctgtcat aatatttata gtcatcatac
    30001 ataatcccag cacatctgaa aatcgctctt gtatctctcc taacaacggg ttttttattt
    30061 ggatatcata tcttaatctg tttaacatag gccttacatg agatgctaga cttttctgta
    30121 gtaagtcatc atttttgaga tttatattta aaaatcgtga catattctct atcattatag
    30181 atgaaacttt ttcactttca cttaatctat ctgattcatc attgtaacta ctattatttt
    30241 cgctactaaa tccagatgat accaaaaaaa tatatatgta cataatttca tctttcgtta
    30301 tttttactct gtatctattt tctattttat ctataagtgt actgacattt ttatatacta
    30361 actcgtccaa attatctaca gaaatttctc tttcttcctg agattctatt tgattacctt
    30421 cttcgattct ctttaaacat ataagtatat gggtaattaa atttatatag tagggctgat
    30481 ttatagtata tcctaaattg tattctaatt ctgtaattat agtttctaca aatataatag
    30541 aatcaatatc aaataaattt atcaatgcac taaatgtagc agaatctaat cttgttaact
    30601 cagatatatc atgttgttca taattttcat ctaataaatc atccatcatt ttggcaatcg
    30661 atttccttat atccacttct ttacctataa tcttagttcc ttctaaagtt ttattaagtt
    30721 ttaaattgta ttcttttatc catgcctcta tatatttaaa atcatttact atagaagttt
    30781 tacttacata atatttatct gctaactgat ttattgaagt tatattattt gaatttagta
    30841 ataaatactt taaaatctcc attcttctct gctctactga taaagattta ttttccttcg
    30901 attgtatatt taaactatta attaagtcta tattcttctt tgctaaatct tctattaata
    30961 ttccatagcc tctttttata tcaattttta tattaaaagt ttctaaatat ttctcaatca
    31021 tcttcaaatc tttttgtaaa gttttatcag atacatttaa tttatcttta aagtatttta
    31081 taggtctata tttattttcg tttagtatca atttaagaaa ttcaatttgc ctcgacacaa
    31141 gcatacttag ccctccctac ctatgtttat atatttctat gtttatatta agtactattt
    31201 taacatattt actaactatg taaaattact aagatacttc tgtatcataa aagaatttat
    31261 gatacacctt actaaattga tataatagat aatataattt caaaataaaa attaaggata
    31321 tttagaagta gttaactgat tctaaatatc cttattatta ttctatatac ttgttgttat
    31381 tccattaatt atttttacta ttatttataa tttaagcacc aagtaattca acttcactat
    31441 tttcactcct tatagtaggc tttgttaccc ctataatcaa tgctgttatt actgtaccaa
    31501 tcaatataca agctatatat gcaactggtg cactacatgc aaatggtatt acaaatattc
    31561 ccccatgtgg tgccattaaa gttatatcta aactcataca tattgcccca cctatacaag
    31621 aaccaattat atttgctgga atcattctta atgggtctgc agctgcaaac ggtattgcgc
    31681 cttctgttat gaaagatgcc cccattatag cagttggtag agatgacttt ctttcttctt
    31741 tagtaaactt atttttgaat attaacatag ctaatgatat tgctaatgga ggtaccattc
    31801 ctcctaccat taatgctgct gatggttcaa atatattact tgaaaacata gccaatccaa
    31861 aagctgaagc tgttttatta ataggtcctc ccatatctga tgccatcatc cctgctaata
    31921 ttgcacctaa taatacttta ttagttccag acatactttg taaccaagat tgtaaagctt
    31981 catttaacca tgatgctggc gtattaacta caaagaacat tatagctcca ctcgtaaatg
    32041 caatcaaaag tggacatatc aatacagcat ttactccttt taatacatct ggtaaatttt
    32101 ctgttatctt cattactcct aaagctatat atcctgttgc aaaaccagct accataccac
    32161 ctataaaacc tgaacctcca ataactgcca taaaaccagc tatcatagca ggagcaaatc
    32221 cttgtcttcc tgctattgat ttagctataa aaccagcaag tatcggtata aataacttaa
    32281 atgctgaatc gcctccaagt tgtccaaaga atccagctat agggttgtat gtttcatgag
    32341 ttgggtctga tgcaaatata ccaaacataa aagctatggc tataccaatt ccacctatca
    32401 ctacaaatgg aatcatttca gatacaccac tcattaagtg cttataaaca ccctttttct
    32461 ctgacccttg aagcatttct tttgaatctt ctaaagtctt tccacctggt ttaatttctt
    32521 tagccattcc attttcagcg tttataatta aatttttagc taatgaaaca ttcttagcat
    32581 ctactacttt cttttgtagc actttctttc ctataaatct actcagttga acttctttat
    32641 cacaagctat tattacgtat tcagctcttt ttatatcttc tttagtcaac ttattttcta
    32701 cacctatagc tccatgagtt tctattttaa cttcatatcc aagttcttga cctgcttcct
    32761 ctaatgcttt ttttgccata aaagtatgag ctatacctgt tggacatcct gttatcccaa
    32821 ctataagacc tttattttga ttattactaa aatctcctga ttctgcagct ttattattaa
    32881 atatacttaa tatttcgtat ggagtttctg cacttagtag atgcttaaga aaattttctt
    32941 ccattagata tgtagctagt ttagatataa tcttaagatg ttcatctgaa cctgattctg
    33001 gaactgctat cataaaaaat gacctaagtt tttgaccatc attatctgta atctctctat
    33061 ctgttcttaa atacatcatt acaggttgat ttactacatt tgacttagca tgaggtatag
    33121 ctattaaatt acccatatta gttgatgatt ctttttcgcg tttattaata tcagctataa
    33181 acttttcttt attatttata taatttccat ggtacaaatg atttgccata taattaatta
    33241 catctttttt tgtttgtaat tgtttatcta gtacaataca atcgcttcgt agtattttac
    33301 ctatcataaa ttctcccctc cttttaattt gttacctcat aattaatttt tatttttata
    33361 aaagcacttt aacttatcta tagcattgaa tagattcatt ttaaactcta taacttctct
    33421 tgcagatttt atacatggtg gatatatagt atctggctca tataagcttg ggttttgttc
    33481 taatagttct ctgcacttct tataatatgc cgacttaaca tcactcgaaa tatttatttt
    33541 acaaactcct agtttaactg cttgtgctat ttcttcatct ggatttgatg aaccaccatg
    33601 aagaactaaa ggtatatcta ctacttctct tatttctttt aataaatcta gtttaagctc
    33661 tggtttaaaa ccttttggat atataccatg tgctgtacca attgcaatag ctagtgtttc
    33721 tactcctgtt ttttcaacaa aatccttagc taattttgaa tctgtatata ttatttcatc
    33781 agtaccacct tcacttgatg ttcctgttgt tcctattgtt ccaagttctc cttctacgga
    33841 cacatttaat ccttttgcta tttctactat ttccctagat atagctacat tctcttcata
    33901 tggtaaatgt gagccatcaa tcattactga tgtaaatcca catcttattg cccttaatat
    33961 ttgttcttta ttttccccat gatctaagtg tattaccata ggtactttac tcttatttgc
    34021 ttcttctatg caactagcta caaagctatc tcctagaaaa cttagctcat ttgggtgtat
    34081 tgcaagtatt actggtgcat ttttttcgtt agcactctgt actactgctt taagtatttg
    34141 cccacttcct atattaaatg ctggtacagc aaattgattt tcttgtgcca cttttagcat
    34201 ttccttcata tttattaaca tattgtacct cccgatattt taaattttag gttgaatttg
    34261 cttcttgtta attttgttgt tgtttatatt taaataatat cagggtaatg aagatcagaa
    34321 aataacaatc gttttcctta gtgaaaagga acttttatta tacactctaa gttccttttc
    34381 actaaataat ttttagaagt ctgcatcata gttaattata tttctcatat acatcttctc
    34441 tttttaagtg ttttatgctt tagccttctt aactctttcc aataaacaat tagatagttt
    34501 agctataaat ttaaagatat tcgtatcgta gttagcacta tattggaatc aaaaaaatta
    34561 aaaagatact agatagcaga taccaattat taatacacca taagtcatag atacttctat
    34621 cttaaattct tgcatattag ttacaataga aattaaatag gactattata aaaatcgtaa
    34681 ggtaagactg acatttattc tccaactata caaatgaata ctaatatagc tccttctaat
    34741 taaatcatac tatataaatc atatatatcc caatttttaa ccttacctct ttatatttac
    34801 tttttaataa aaaaagatat tgactaaata gtcaatatct tttagtggat ttaaataccc
    34861 acgattttaa tctaattttt aatggtttcc ttaacataat cttataaata ttaaaattta
    34921 tctacctata aaatttctcc attaaatttt attacatttt tataccaatc aaaagatttc
    34981 tttttatatc ttttaagagt cccacttcca tcattatttt tatctacata tataaatcca
    35041 tatctttttt tcatctctcc tgttgtaaat gatactggat ctatacatcc ccaaacagta
    35101 taccctataa catcaacacc atcaatttca atggcatttt tcatttccct tatatgacta
    35161 gccaaatact ctattctata atcatcatct acagtattat ctgattttaa tacatcttct
    35221 gctccaaatc cattttcaac aatgaatata ggaagttcat acttatcata tagttgatta
    35281 aggtaaaacc ttagacctac agggtctata ttccatcccc aatcagaaat ttttaagtat
    35341 ggattttcaa ctacatcagc ctttcctgcc gagtcattac ctgttgtttt catagtttta
    35401 tcagctgtta ctacagtagt taaataataa ctacatccaa taaaatcaac tattccttct
    35461 tttaggattt ttttatcttc ctctgtaata tctaaattat aattttttct ttcccataat
    35521 tttagtgtat gtcttggata atgacctctt acatgtacat cagtaaacat aagttgttct
    35581 ctattagatt ctacaaattt aatcatatcc tctggattgc aagaataagg ataacttggc
    35641 atagctgcca ccatacatcc aattttaaac tcagggttta tttcatgacc tatcttcaca
    35701 acctttgcac ttgctacaaa ttcataatga actgcttgat acataacttc ttctttgtct
    35761 tcctgctctt catagattat tcccgagtta gtaaatgcat aaataggatt tgtagttata
    35821 ctttgattat ttatttcatt gaaagtcatc cagtacttaa ctttatcctt gtatctattc
    35881 attaccactt cacagaagtt tacaaagaaa tctattaatt ttctatttct ccatccacca
    35941 tagtttttta ctaaatgata aggcatttca aaatgactta aagttattac tggctctata
    36001 ttgtatttta ataattcatc aaataaatca tcataaaatt tcaatccatc ttcatttgga
    36061 gttgattcat cgccctttgg aaaaattcta gtccaagcaa tacttgtcct aaaacactta
    36121 tatcccattt cagcaaataa tctaatatct tctttataat tttcataaaa attaatggct
    36181 tcatgattag gataatttaa accctcaatt actccatctg ttatctttct tgaaatagta
    36241 tgagtacctg cagtcatcac atctgcaata cttattcctt ttccaccttt attatatcca
    36301 ccttcaactt gatgggcagc aactgcccct ccccataaaa attcttgatt agatttcata
    36361 gaaatatctc ctccagtata attaataaac aacttttatt acaggcgttc caattttaat
    36421 atgtttattt tctttaacta ttacatctgc taaatcattt gtgttagtta gtattattgg
    36481 tgtaacaata ctataccctt caccttctat tttatcctta tcgaaagaaa caatcctatc
    36541 tcctttttta actttatctc ctgcattcat atgagtagta taatactttc catctaacat
    36601 agtagtgtta agacctacgt gtattaatat ttctacacct ttatcagagg taattcctat
    36661 tgcatgcttt gtaggaaaaa tagttgttat tgttccattt acaggagaca caacttctcc
    36721 ctttgaaggt attattgcca tgccattacc tatagttcct gatgcaaaca cttcatcttc
    36781 tacttcagat aactctattt gtaagccttc tattggagat aatatctcct ctataccatc
    36841 atcttcatca aaagcaactt cttcattacc ttcttcacat tcttctttac tcaatccaaa
    36901 gaaatatgac aatactgctc ctagcactaa tgctgttcct attcctaata tatatcctag
    36961 gaatggtgta taaactggca ttgagaatat attatgaaat acatatgcat tacaagtaac
    37021 accaaataca ccacatatac caccaccaat acctcctgca atagccaata ctggaatcat
    37081 tcttctgtat cttaatataa ttccataaat tataggttct gttactcctg ctaaaattcc
    37141 tgtaactgct gttgaacctg ctaatacctt taattctgaa ttttttttag attttctaac
    37201 cttcataaat aaacctattg caatacctat ttgagcaaat actgctgcaa cagctgcacc
    37261 ttctattggg tctccaccca ttgtagccaa gttttgcaaa gtaattggtg tgaagcccca
    37321 gtgtagtcct aatactgcta agaatggcat agctatacct attgcagctc ctgcaattac
    37381 tctgttaaat tcaaataatc ccataaaaat attagatatt atatcaccaa cattagttgc
    37441 tattggtcca aataaaatca cagttaaagg aaccatgact aataatgata tcatcggtac
    37501 taagaataat tgtaaatcct ttaatataat cttctttaaa agcttatcaa catagtaata
    37561 aataaatata gcaacaaata tagggaatac accaaaagaa taatcaattg ctgttactgg
    37621 catcccaaaa aagttagcac caccttttgc tccaattaaa gctgtaaaat taggatctaa
    37681 caaagctgct cctatcactc caccaacata tggatttgca ctaagtttta tagctaaggt
    37741 aatacctaag aatattggta aaaagtaaaa tacagcattt ccagctgctg ataatatagc
    37801 ataagtgcta cttgtatcag acatccattt catagtagtt agtattgtaa gcagtgcctt
    37861 aatcattcct gctccagcta gtgcaggtat taatggagaa aatgcacctg aaattgattc
    37921 aaatatttta gaaactattg aaactttttc tccctgttct tcagtatttt gtccttgtaa
    37981 aactgctttt tttataatag tttcaaagta atcagttact ttatttccaa ttaccacttg
    38041 gtattgtcct ccactattta ctacagatag tacatccttc atttttaata actcttcttt
    38101 gttagttttt gaagtatctt tcagcttaaa acgtagccta gttgcacaat gaactaaact
    38161 aataatattt tcttttcctc cgacatattt tataatttct tcagactctc tttcaaattt
    38221 catacaatct atcctccatt ttcataattt tatgtataaa aatagaccta aatcaataca
    38281 attagatatt aaaaactaat tataccaact taggtcatgc ctgccaaaca gtaacaatcc
    38341 tacactattt actttatatt tgataatcta tttaaatgca atgttaagta caacaattca
    38401 ttttcgctaa ttttccattt atacgtcttt tcaagaaagt tttttacttt ttttgcacaa
    38461 ttgtaatcac ttttatattt catttttatt atatctaaca atgatgtgtc tacatttgta
    38521 ttctcaccac ttaattgcct ttttataaaa catcttaaat gacttataaa ccttgtgtag
    38581 tcaaaggaat attcatttat ttcgattcca tagtgatact ttatgatatc taatacatta
    38641 tcaattatct tagttaacaa taaagtttct tgcatatctt ttgtttctaa ctgagcattt
    38701 gcaaagtgta tcgtaataaa tgctatttca gaatcaggaa tatttttatc taattttttt
    38761 cttaaatatt ctacagcttt cttactaaaa ttatattcat taggatatat ttgtcttatt
    38821 tcccattgaa gcgggctttg aaatactaat ccttcatcca ttctttttaa catataactt
    38881 atatgttctg ataatgtgat taatatacta tcattaagat tatcacccaa ttcttctctt
    38941 cccatttgaa taatttcact tacaagctca acatctttta aaggtatcct atctagtagt
    39001 gaatgtaatt cacttaatga ttcctcatta ttgaatataa atttcttttc aattttatct
    39061 atttcaacta aatctttagt aaatttatta aatccaattc cttttcccat taatattact
    39121 tcttgtcctg aattatctct ggcaaataca acattattat taaatacttt ctttataacc
    39181 ataaactacc tccactgtaa acaaaaagag acctaaaaaa gactaataat actttaagca
    39241 tttactagaa tttttaggtc acgcctgatt acatctatct cagtaacgat ccgtttattt
    39301 atctgtatga taactttatt ttcattataa aataataact gtacttagtc aatatataat
    39361 ttcatgtata tctctactag attattgtca taagtattca ctcattctac tttttttata
    39421 tgatttatat aatctaaaca tgctaaaata agttttgaag ttatttcata acaaaattaa
    39481 ggtcatatat tttttattat atatactcga ttatttatcc atatataagg aaatccttta
    39541 ttttgtaact acaataactg cctaagtttt gattttcttt tatcttttac ttctccttat
    39601 taaaaaataa ttcttttact gttgtatcta aggctctaaa cagtttaatc atcaaatcat
    39661 tgtttggatt attaacctta cctaacttac tatatagctt tttaactgta tatctttaat
    39721 agaccttttg gtatgctaat ccattttata acactaattc ttgaatcaag catatattac
    39781 ccttacaaag catatcttat accctctgta gagttatgat agttgatgaa cctgaagaaa
    39841 ttacccttac aagacatatc tgatacaacc tcacttatta gtttatatgt ttcagaagta
    39901 tataaataac acatacttac ttccaaattc ttaactgttt tcttagaaaa ttctaatatg
    39961 atttccttac atagcgatta taacagtgtc ttattagatt tcataaaatt atacatcctc
    40021 tttacattta aactttaaat ttttatctat tgtttattaa ttaactgtat attcactatt
    40081 ttttatcatt tataatactc ttcttattat cttaaaacaa ttataatcta accttaatca
    40141 catattatat aaatattttt aataaactta ataattaaat aactatattt cattatccat
    40201 cttataaatg tttataaact ttccactatt cttcttcaat aaattcaaac aaattttcta
    40261 ctgtagtatc gaatacttta gcgatatcca tagctaactt caaagaagga ttatatttcc
    40321 cattttctaa gtgtacaata gtctcacgtc ttaccccaac caatttagca agttcatttt
    40381 gcgtcataag gagtttttct ctgtattctt taatttttgt tttcatcaat attgccactt
    40441 agttacatat ccccctttta tcaaagtata tatacaacac taatttagat aaagactgta
    40501 taaataaaac tgcaatgagg attatacctg tatctaggtt tgatatattt atattacttg
    40561 tataaggtgt tgcaaagaaa atagatatta ttactataga atatatcatt atttttattg
    40621 caatcttatt aacctttgat agtataaatt cagatgattc atcaactaaa tcattatatt
    40681 ttttattata aattgaataa catccaaaaa ctattaacca actcaaccct ggaagagaag
    40741 cagtgcttgg acctttaaaa atatatttag tagctaatac agctataaaa aaataagtta
    40801 ttacaagtaa ttccaagatg agctttgatc ttacaccagt ttctgattta gacatataaa
    40861 atcactcctt aaaagttata tattctctat attttttaat ttttgttttc ataaatatta
    40921 ttacttagtt acatattccc tttttatcaa aatatatata caaaattaat tttgacaaag
    40981 attgtatgaa taaaactgct aagagcatta tacctatatc caaatttgat atgtccaaag
    41041 ctcttgtatg attaactgaa aagagaacag ctattacaaa catagagtat aacattattt
    41101 ttgatgcaat ctgatcaacc tttaacaaca taagttttga tgcctcatca actaaatcat
    41161 tatatttttt attatacatg agattgcaca cccaaaaagc taataaaatt ataaaagtaa
    41221 accaaatacc ttctccttta aaaataaact tttgtaataa caagtctata aaaaaatagg
    41281 atagcatcat taactctgaa acaagatttg ccttaacacc aagctctgat ttagacatat
    41341 aaaatcaccc cttaaaagtt atatatttat aacaccttat gttataaata tataactttt
    41401 ccaaataaat tgcaatagaa tattgaaaat attcaataat atcttcataa atatatttta
    41461 taaaagattt tataataaac attacaatac agtactaaat tagtttattt catctatcat
    41521 ctcaatcata tcatttacta actattattc taatgagcat ataacattga aatttataat
    41581 tatacaacct aaatgcctcc caatgtaccc tcaaaaacat catttcctgt aactgaagta
    41641 taattggtat attttatcac tgaaataaaa aaacactagt caataaagac tagtattttc
    41701 aagtatttta tcattctttt tttaattatt ggagacgaat catcagaata atgcccataa
    41761 tttatctata tgcaaattct aaatttaaaa taaagtttca gatgaattta ctattctatg
    41821 ctatgataca acagaaaaaa ctgaaatcta tgagtggtag cttcatataa tcctagttcc
    41881 tacagtaatc aaaactgagg tttattctat atgtaactaa tgataaattt tattatagga
    41941 gttattagct ctatttgtgt tactataagt agtaattata tatatgataa ttttttaaca
    42001 cttttctgtt ggctatatag aaagtggttt agaatttaaa tttaaataaa atttaaattc
    42061 accaaaaaga aatctatatt agaaaccact actctattcc accagattgt aattttttgt
    42121 tctttatatc acaatgctat accatattaa attgaaaaat aaattttaaa tttatttgtt
    42181 acaattcatt aattcaaaaa aatattttga gtcatgagtt ttgtaaagat ttagccatga
    42241 atttaatgct tctgattcaa aaacatctaa aagtttcaat acttgaaacg taaattccaa
    42301 cggagcgatt cctgaagccg taactaaatt ttcatcacta actacagatt ccgttttata
    42361 atatttttct ccagagtaat ttggtattac cattttaaga aactctaagt cattacttgt
    42421 atgatttcta acatctaata gccctttttt agctaggcct aatgtagctc cacatatggc
    42481 tgcaactata gaatcttgta ttaaagcttc tttaactttt tctaatatta tctcatgatt
    42541 catggataac caagtatttc cccctggcaa aattaataaa tccttacttt ccatattaaa
    42601 ctcatcaact gtaatttcag gtaaaacttt taacccaccc attgttataa taggattttt
    42661 atcaattcct acagtaatta cttttagtgg ctttaatcct tttttaaaat atcttcctgt
    42721 atttaattca gcagttaaat atgccacttc ccaatctgac atagtatcaa atacatacat
    42781 atatactttt ctatttttca tcttttttac tccttatgta attaatttat atatctaatt
    42841 ataaaataac ttaactgaca tattcagtca gttaagctat taaatttgat aataatcaat
    42901 taattctagt aaatcttcaa ttattttctt cctaaggctt agtggttcaa ttacttgtat
    42961 tgtctttcta taaggtaaaa gtatatttgg tatgtacttg catattactt cctcttcgag
    43021 cataaatatt attttattag gtgttctttc tttcaagtag tgccctaaaa accaatgttg
    43081 gcttaaacta tctaaagaat ctatactccc ttctacaact aattgaatta tattttgttc
    43141 atcttttatt tcaggtataa ttccttttat aaaaaattca cttgctgaaa attctgtcgg
    43201 tctgttaaat gtatttgatg tttctatgat ttcactaatc ctatccactc tgaaactacg
    43261 tacctcattt ctcatattac aaaatgcaac tacgtaccaa ttattattcc agtgaacaat
    43321 tccatatgga tttataattc tatattttga ttttgcttta cgacctgcat gatagttgat
    43381 ttctacagat agctccttta atatactatt ctccaatttt ttaagtactg attctataga
    43441 cactttccca attggtttta ttacttcaag ggctcttaag tggtttgtta aaatatcttc
    43501 ttggttttga tttgaataca tttttaactt taatatcgat ttatctaatg cttcgtctaa
    43561 gaagtatcct tcttttttag caaatagagc tgcatgaagt agagattttt gctcttctat
    43621 atcaaaaaaa agaggtgctt tagtaaaatt atttaaaagg ctatacccac cattatgacc
    43681 tgtatctgaa attataggta ctccactcgc agaaagtaca tcaatatatc ggtacactgt
    43741 tcttatattt atttctaatt tttcagctat ctgttttgct gtaatttttt tgtcagagtt
    43801 taacatccac agtatagaca tcatattgtc aattttagcc atgtagtttc acctctttct
    43861 atttgttata taaagttatt atataacttt ttgattgatt ttttacaaaa aaacattagt
    43921 aaactgctaa taatttatac taagatttat ttcaaatatt tatagatagt ctttttctat
    43981 agttaagtta tccattaaat tacatagtag tatatccatt ttagttgata tattttcagc
    44041 tacctccctt gaatattatt acaataagtc taaatcttct ttcttccata aatatattat
    44101 gaggaaagac tatcatcttt aatggtttaa tagtataaaa gatattaatt taaaaaaatc
    44161 tatttttata tcagatgggt attgtttttt ataaaactga aaaaatcacc taatagaatc
    44221 tatgattttt taacataacc tccataaatt agtaccaatt atcacttcaa attcaaattt
    44281 ttatctgaag aatatacaat catatttcca tactcaacat aatattgagt gtttggcttg
    44341 tatttacaaa ttattattct aacaaaaaca actatacata gattaaaatc accttctaaa
    44401 cataattatt aaaatttaat taatgatatc aattccatta atctctttta ataaaaaatt
    44461 ctcttttcta tatgaaaatt atttcaaaac ttttaagtta aatacaaaaa tgactataaa
    44521 tagattttta tttacacaaa tctatttata gtcactatag tttatccaat aaaataataa
    44581 aataaatatg tacacaataa atgttattta cgtcttaagt atttatttgt tagattttta
    44641 attaaaaaaa acaagctaat gaacattaat gctaaatcta gcattatatt actttgatct
    44701 cctgtttgta cattttgacc tacattacta tctaaacttt catctgtatc tatatttata
    44761 tctggttttc cattcccatc tgtatctata tttatatccg gctttccatc cccatctgta
    44821 tctatattta tatccggttt tccatctcca tctatatcta tatttatatc tggttttcca
    44881 tctccatcta tatctatatt tatatctggt tttccatctc catctatatc tatatttata
    44941 tctggttttc catctccatc tgtatctata tttatatctg gttttccatc tccatctata
    45001 tctatattta tattcggttt tccatcccca tctgtatcta tatctggttt gctatttcct
    45061 ccattatctg ggtctggttt actatttcca ccgttatctg gatccggttt gctatttcct
    45121 ccattatctg gatctggttt accattgcca ccgttatctg gatctggttt gctatttcct
    45181 ccgttatctg gatccggttt gctatttcct ccattacctg aatccggttt gctatttcct
    45241 ccattacctg aatctggttt gctatttcct ccattacctg aatccggttt gctatttcct
    45301 ccattacctg aatctggttt gctatttcct ccattatctg gatccggctt gctatttcct
    45361 ccattatctg gatctggctt atttagattt ggattacctg tatcataacc tcctgagcca
    45421 gtatctacat ttttatcagg cttccaataa tcatctactc catcattatc tgtatctatt
    45481 gctggacgat tataatctgt atcagggttt ccatctccat tggtatctat atttttatca
    45541 ggtttccaaa taccatctcc atttccacct tctgtactag gcttccattc acctgtatta
    45601 tcagtatcta tgttaatatc tggcttccaa tcaccactcg tatctatatt gatatctggc
    45661 cttccatcac catcagtgtc tatatttata tccggtattc catccccatc tacatctaca
    45721 tttgtcatat ctaactttaa cttcttttca tcctcactac cttcaatgta atttatatca
    45781 tctccaatat attttacagt aatagtttgt tcagtagtaa aaatatgatg attgctatct
    45841 aaaggtctcc attcaataga tgcagtacta taattatgac tctcactacc cttattatga
    45901 gtttttaatt ctactggatc tttatattcc tttccattaa tatagaattg tacgtaacct
    45961 cttggagagg cacaatctgg tccttctttc ttatctggtg aaatagtaac atttaatgta
    46021 aacgtatctg ttggtttaaa aacatcagtt ttagctttag actcttctac aactaatgaa
    46081 gtttctgtat cagcaggaat aatttctgcc ttataatatg ctctatgccc ccaataagct
    46141 tcattaaaag gatatacatt tgaaaactgt gttgatgtaa tgcttaattg atattttcca
    46201 gcatcaactt gctttgtaag gtcatcactt cctaaatttg tatctggttc cattgtttcc
    46261 tcatttaaac gttgagaact aatagtcata aattttttat ctgtgagttt ttcaccttta
    46321 ggagtaatta ttggaatacc cccatctttt aatatccaat ctaaaaataa tttttctaca
    46381 tcttcttcaa atggtaatcc atcatatctt ttaataatca aatatggtgg agtatcatca
    46441 atagtaaatt cttcatattg ctttaaaaat tgagaacctg aacctatatc tttaacataa
    46501 aaatcatctg gttttatatt tcctccagta attttatcta taacaactaa attaacagat
    46561 acttcagatc ccttaaattg atcagaaaac cataagtaaa gaaccccttg atcatctgta
    46621 taactaggtg ctccataagg ataaattttt ccatcaatta gcattttaaa atcatcaact
    46681 aatgtagtac taactttatc ttgtcctaaa tactttaaag atattttatt cataaaaact
    46741 tttgttttct tttctaaatc accgtatgca actgctccac ctaaactttt gaatgttgtt
    46801 gcttttaatg aaccacctgt tactataaca tctcctgttg tagcacttag gtcaaaaatc
    46861 caatctccca ctcctgtcat ataaggtaaa atcgttcctc cagttacaag tatacgatat
    46921 cctctatttg ttcctggatt aacacatcca tccccaaatg cactaccatg tgcacctcca
    46981 tatgaatagg aaagtccacc attaattgta atatttccac tataaccaga acctgtgcta
    47041 ggatctacta ctgagggact taatgcattc tttgttgttg tatagtatcc tccacctatt
    47101 ccagctccat ggtatgcacc tttagcagtt atagtaccac cattgattgt gatatctcca
    47161 ccactaccat taccgcctcc acctattcca gctccatatc ctgtattacg actcgattct
    47221 tgacctatag cagttatagc accaccatta ataataatat ttcctccact ttcagtattt
    47281 ccaccgccaa tacctgcaga ataataattt ccaacaactt ttaaacttcc tctattatta
    47341 ctatctagta gtgtaaggcg atctcctttt tttaacttgt ctccattttc tagagttaca
    47401 tctctaggaa tttttccacc ctcaggaact ataaactctc cttcaatatc tctatttaca
    47461 acagaatcat caatagttag agtagtacct tttcctgctc tcatacctgg ataatataca
    47521 tcacctgact ctagcttgtt ttcactacca tcttgtaata taacatgtgc atatgcacca
    47581 ccatctttat ctggtgttaa agtaaatggg ctattagatg cagttttaat atttactcca
    47641 tcaaatatta attcagcttt tacatcttta ggtataacaa tcctatgtgt tgttggagta
    47701 tttggattat tattttgaat tgtcatttgt tttccactaa gaatagttaa aacgccactt
    47761 gcaaatttaa aatcgacatt tatttctcca ccactaattt taaagtctcc tacagatgta
    47821 ggatcttctg cagtggcttc ttccacaact aatgcattca tatcttcttc tgcatttcct
    47881 gcattagaat cttcttctgc atttcctgca ttagcatctt cttctgcatt tcctgcatta
    47941 gcatctcctt ctgcatttcc tgcattagaa tcttcttctg catttcctgc attagcatcc
    48001 cctcctgcat ttcctgcatt agcatcccct cctgcatttc ctgcattagc atcccctcct
    48061 gcatttcctg cattagcatc ccctcctgca tttcctgcat tagcatcccc tcctgcattt
    48121 cctgcattag tatctccttc tgcatttcct gcattagtat ctccttctgc atttcctgca
    48181 ttagtatctc cttctgcatt tcctgcatta gtactttctt ctatagtatc tgcgaaagta
    48241 tttgacgcat taaatgatgc tactgatcca agtcccattg agatacttaa aatcattgat
    48301 agtgctttct ttttacattt ttgttgcata aattccccct ccccttaata atttttaata
    48361 tacactgtat acatccttat atacactcta ataattctta atatacactg tatacatcct
    48421 tatatgcact ctaataattt ttaatatata cttaaaactt atatttgtca atgaatatac
    48481 tgtttttttc aaccttatat attataagta ttcattattt gctaaataac tacaataaaa
    48541 attttaatta tataaaattt atttaatttt ttatataata atactaaggg gtaattaatt
    48601 gaaaaactag taaaaatatt aataaatatt atttgcatta ttgcgctaac tttctctagc
    48661 ctttcgattt acataaaatt atctgaatat aaaaaagctg atgaagtata tacggaactc
    48721 agagaaaaca ctatcaataa tagcaaacat caagaacttt atgataaaaa taatgattat
    48781 agattctggc ttaaaataaa caacgtaaat ataaactatc ctgtagtaca aggatataac
    48841 aatgatttct acctaactca tgatttttat aaaaattatc ttcctttagg tagtattttc
    48901 atggattata gaaataattt tgaaaatgat aagagtttaa tagtctatgg tcattatatg
    48961 aaaaataaaa ctatgtttgg tcaactagaa aactatactg atgaagtatt tttcaaagaa
    49021 aataacttag tagaaataaa ttataaagta caaacttata cttatgaaat tttttcagta
    49081 tatactgctg acttaattaa cagagattat ttaagtatac actttaataa taatgatgag
    49141 tttaaatatt ctttgaatta tataacctaa aaatcagtac acaaatctga tataaaggta
    49201 gatatttcag ataaaattat aactttgtat acttgtaact atgaatttaa agatgctctt
    49261 actatagttc atgctaaatt aatttcaaaa aagagaccta taagtaggtt tgtgtaaatg
    49321 cagacttatc tacagtcttt tttgaacgta aaattggtaa gtatggaata atatttatat
    49381 taaacttttg taggcaaaga aatgaaaaat caaagagaaa taattattac agatttagat
    49441 taccaagctg aattaagaaa gtgtaaaact atggaggatg tagttggtga agatagtata
    49501 taatagctta acttataaat tatcttggtg atattaatga agtttcaaag tatatattat
    49561 ttattgatat aaataaaatt aaatctgttt ctaatagatg tacctttgtt tggagacaaa
    49621 ctattgaaga aatataacta aaatgttgaa gtagctacct gactttattt tgaaatgcga
    49681 acaagatttt ggcattaaga taatttagaa agaatcactg gtacacaagg atgtgaactt
    49741 agaatgaata gaagtattca ggcataagga gctttcaccc aaataaaaca tagtatgaac
    49801 tttaaaagaa ttctaatcaa aggcaatcaa aatattcttt cagagtttat acctgtagtg
    49861 ttagcctata gtatttctaa gtttcacaaa taagataatc attaataaat gtagtatgta
    49921 tattcatcct ctcaaaaata ttttttaatc ttacactttg taaattattc tattttaaaa
    49981 ttgtattttt atacctttat ttcttatgac cgttttcaag ctcaaatttt gcataaatat
    50041 aaattaatga aaagcaagta aaaaaagaac tgtcgcacag caatttaaaa ttactcattc
    50101 gacagtcctt atttcgtgga ttaatgttgg ataagaatca caagaataat acccactatt
    50161 ttatttgaac tatccatcta gtgcttcaaa cacatctcta agatactcat ttggttcatc
    50221 attaaataaa tttaatatct tttctgctac tactcgacct aataaaggtg gtactgcatt
    50281 tcctatctgt tgatatacag aatcttttgt acctaaaaac ttataactat cagggaatga
    50341 ctgcaatcta gccgcctctc ttgcgctaac agctctgttt ttaataggat gtatccacat
    50401 agattttctt acatttacaa cagtatctga tggcttatca tatactagtc ttttataaat
    50461 agtattttga gttctttctg gatcagcata agttcctttt aactcatctg gcaaagaatg
    50521 aaaattattt ccttgattta tatattcaaa tctttttagt gcgatatttc ttgtatctgt
    50581 acatacatga ttgtatattt tattgctatc caatattatc tttctataaa aatctttttc
    50641 aatattatta ctattttttt caaaacaata atccatacta cctttagaag cctcatattc
    50701 agctaaatcg cctattgcat ctcttactgt aacataattt tctccaacta taggcttagg
    50761 agtttctatc tttttatttt ttaagaagtc tttttttgct cctatcaata caaatctttc
    50821 tctattttga ggtactccat aatcaattga atttagtgca cttccattta atacatatcc
    50881 tagatactca aaggatgcat ttatataatc tattataatg taagtatcca ttttagctat
    50941 aattttatta tcatcaagtg tattttcgaa aattacagat tcagatttta actcatatat
    51001 tcctaaaaat aaattttgaa tatccaagaa taagttcaaa taaaatattt gttcatctga
    51061 taaatttcta ttatataaca tattttctaa tatatttttt actttattta ttaattctaa
    51121 ataccatttt ggcatttttc cccttgtttc caatttttct atggtagatt ttactttctt
    51181 ataattagat attttattta aataatcaca tatatccttt tttttcttaa taattatttt
    51241 caaatttttt aagtctatat ttgatataat atatgattca atatcttcta tactaataat
    51301 attaaataat tcatttatat actcagttct atcatataaa acactatctt tattataaat
    51361 atttaatttt aaattattta ttatatgatt tttatctttt ttagtcaaat aaaatgaatg
    51421 cttatttgaa gatatagttt tgacattttc cattacaaat acatttggct ttaatttatc
    51481 aatagcatca acatatagct taactaattc attatttcca tttataattt ttcttttttg
    51541 tctattagca ttagaaaaac cttgacatgg cggtcctcct ataacaacat ctatcttatc
    51601 gacactgttt aatatatctt gaaaatctaa tcttttaata tcacaataac gcttaacact
    51661 cggatgattt tcaaggtatg tttttgctgc gttatcattt ttttctacaa aagccaccat
    51721 attaaatttt ttagtcattt caaatcctaa gctcaaacca cctgcacctg caaaaagatc
    51781 tataacatta tacattctga catacctcac attaactttt attgcagcat atcatatttt
    51841 ttttcacatg tcaatttttg aataatcatt tcaaatttct tatacttgta atagctttta
    51901 ataaattcta atatttttac ttacacatta tttttcttat ttatgtcttc tggataatct
    51961 attcaaataa ataacataat atatttttta tttatttatc aatctttttt tatattatat
    52021 accatatatt attttttagt aatataatta taatatagaa taaaaactat tctaataaac
    52081 aatagtaact actaaaggag atttaaatgt taactacaaa tatccattat attcttgata
    52141 atgatatatg tgaaatttat tttaataaac aaaggctaac aaattctaag tattatcaag
    52201 ataatattaa tgtattaaat tatattataa atgaaaaaaa taataactta attatcaatt
    52261 ataatgacaa atacatatat gctatttatt tgttgaatat agctataaac tcatacttaa
    52321 ataatacatt aaacccaaat aatcacattc ttacaaaact cgataaaggt atgcccctgc
    52381 tctacaaggg tcaaatagtt atatttaaaa atataaataa tacacacata actttaggac
    52441 ataaaaataa aacggataca acacttatac ctattgactc ggcttatatg cttataacct
    52501 ataatggtca tttagaagtc aattctatgg gcaaaactcc agcatctaag acttttcaaa
    52561 caaagaatgt tctatcatct ttaggttttt cagacttaaa aaatatgact ggagtaataa
    52621 atgattctac actgattata ttgccttgta aagatgatat atctgactta gttagtaata
    52681 ttaaaataaa agatattaat aatacttata agtttactga actatttcca tgttcatata
    52741 tttcatcaac tggtgccgaa actgattatc ctggaaatca cgctaagcaa atacctttac
    52801 ttaaatttac aactaatatt tctagtgcat ttgaaattat taaatctgat aagtctataa
    52861 aaaatgtatt tataataggt gattatccaa tttataagca tataaatgat tttgaaagaa
    52921 ttttaaatag aaaaaggata gaaagtgtaa atattgtaac ctcaaattca aatataagca
    52981 atatattaga tttaccaaat atagataatc taaatatata ctcttggtct aaagatgttc
    53041 tgttaaccta tagccaagat tttgaaaata cctctacttt tcagaaatta tggctagata
    53101 aacttataaa taaaaatata tgtactactt ctgttgattc taatatctct gacttgatac
    53161 atcaggctag aaaatcactt tattacatat ctaagtatga ttttgatatt tccataaaaa
    53221 actcacttat gatgtgtagt tactctcttc ttaaaatctt agaaaataca ccttttaacc
    53281 tagatttttt agaagaaact ataaagcttt taaatttaaa tatagcaact ccttcagcga
    53341 agctagaaaa tataaaatat ttaatttcaa gtactagccc agatttagaa ttaag
//
LOCUS       DAEPKC010000014        53376 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.014, whole genome shotgun sequence.
ACCESSION   DAEPKC010000014 DAEPKC010000000
VERSION     DAEPKC010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 53376)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53376)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53376
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.014"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            86..223
                     /locus_tag="KR294_000921"
     CDS             86..223
                     /locus_tag="KR294_000921"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239027.1"
                     /translation="MNKTKYYDILKLNLLMKKLKELDKNKINEYKIKVKEIHKINKKE
                     E"
     gene            complement(260..655)
                     /locus_tag="KR294_000922"
     CDS             complement(260..655)
                     /locus_tag="KR294_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0239028.1"
                     /translation="MNRIKELREEKGISLDKLSEDLHINKSTLSRIENGLREPKKSTI
                     EEYANYFDVSTDYLLGRTDVRNSLFINKNEKDYDAENFKTEKELIENMYLDEDMKEVF
                     NIFSELSPDAREKALKVAELFLLDEKNKK"
     gene            834..1067
                     /locus_tag="KR294_000923"
     CDS             834..1067
                     /locus_tag="KR294_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF739 family protein"
                     /protein_id="HBH0239029.1"
                     /translation="MYLNRLEGLMKENRHTQKNVADILGLSSYGFRLKLKGKNEFKAS
                     EIKKISKLYNVSADYFFSDEVAKIAIKEERGNK"
     gene            1067..1855
                     /locus_tag="KR294_000924"
     CDS             1067..1855
                     /locus_tag="KR294_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HBH0239030.1"
                     /translation="MKNLTIIKQNNQFLVESREVAELIEKKHDNLLRDIRGYKKILED
                     SSNLKSQDFFIESTYINTQNKIQPCYLLTKKGCDMVANKMTGEKGIIFTAIYVTKFEE
                     MERELKEQQPKLPTTYKEALQQLLIEVEEKEQLQLENQEKDKVIQLQQPKVLFADAVS
                     TSNNSILVGELAKLIKQNGVDIGQNRLFAWMRENGYLIKRKGEDYNIPTQKSMNLRIM
                     EVKKRVINNPDGSTKVTRTVKITGKGQVYFVNKFKSSKQLSMLS"
     gene            complement(2156..2500)
                     /locus_tag="KR294_000925"
     CDS             complement(2156..2500)
                     /locus_tag="KR294_000925"
                     /inference="COORDINATES: protein motif:HMM:NF018697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0239031.1"
                     /translation="MINRILDLMKKNNITAKQLTNDLEISNSSVSDWKKGKGKPSSDA
                     IVKMAEYFNVTTDYLLLGITCDKTNNINLTKNEQEILSLLHKFDERNQIKFISKVEDL
                     ADKMLEKENDIE"
     gene            2670..2861
                     /locus_tag="KR294_000926"
     CDS             2670..2861
                     /locus_tag="KR294_000926"
                     /inference="COORDINATES: protein motif:HMM:NF024835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH0239032.1"
                     /translation="MNKKCLPKWSKEVKKAMIDRDLKLDDLSEELGLSKYHLSAVINN
                     RLKSPNAKEAICKYLKVKG"
     gene            2894..3352
                     /locus_tag="KR294_000927"
     CDS             2894..3352
                     /locus_tag="KR294_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0239033.1"
                     /translation="MSYEYQNVYQKARENTYLTQEKASELLDISVESLRAYENDKRIP
                     NNQIVAKMVSIYNNNLLGYEHVRRTTEAGVMFLPKLEMKSLSSITLKLHKEIKDYLKK
                     EDDFIDIVEDDVIDEDEEEVWNDVMEKLEGIYEAILKLKLSRNTKISKEV"
     gene            3355..4122
                     /locus_tag="KR294_000928"
     CDS             3355..4122
                     /locus_tag="KR294_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rha family transcriptional regulator"
                     /protein_id="HBH0239034.1"
                     /translation="MKDLTIVKVNNKLTTDSRDIALMVEKEHKILLRDIRNYINQMEE
                     ANKNMSTDLYPSDYFIENTYLDDYKREKPCYAITKIGCDFIANKMTGIKGTAFTGIYT
                     KKFDEMEKALKEKQPKLPTTYKEALQQLLIEVEEKEQLQLENQVMKPKADYFDALVER
                     NLLTNIRDTAKELGVKEKTFVLWLIEKKYCYRDLKGKIKPYSNKMQYFELKEFTTPYG
                     HSDTQTLINPKGREAFRLLLIKDGLVKEKEYQITLLG"
     gene            4167..4421
                     /locus_tag="KR294_000929"
     CDS             4167..4421
                     /locus_tag="KR294_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239035.1"
                     /translation="MSEDIFYGIKNTLDEIAEVQIKNKQGVLKEVGMLISGEDNSCIT
                     HCLDEDLIKFYIKEEAVLTIDKDSHLLCMLDALFYNFLDK"
     gene            4449..4892
                     /locus_tag="KR294_000930"
     CDS             4449..4892
                     /locus_tag="KR294_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH0239036.1"
                     /translation="MKKLGNISNFNLDKQEDKSFNDLDNISICFSEGIRKVVEMNLNN
                     YKNKISKYLNETSKIELLEPKELTIVISKGYPDYLMSVEEASKRLKIDKVFGYELIKN
                     GLLKSVDIGATKVSSYELDDFITRNQGKNIKEMLREMKELREGVI"
     gene            5020..5208
                     /locus_tag="KR294_000931"
     CDS             5020..5208
                     /locus_tag="KR294_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239037.1"
                     /translation="MKIIYKNKVYKVEQDKKLFRITYYDEQRGSKKFNKEKKIKRSVL
                     TRDIELVNLYLPAHLKIK"
     gene            complement(5343..5513)
                     /locus_tag="KR294_000932"
     CDS             complement(5343..5513)
                     /locus_tag="KR294_000932"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239038.1"
                     /translation="MSNKDIYTREEDKRFTLRINKLLFEKIEQLAQKDKRSIGREIEF
                     ILEKYFEDNPLE"
     gene            5656..5814
                     /locus_tag="KR294_000933"
     CDS             5656..5814
                     /locus_tag="KR294_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Arc family DNA-binding protein"
                     /protein_id="HBH0239039.1"
                     /translation="MTNERVRFTFRLPAPLLEKIKNRASIEGSSMNSLILHILWDYIK
                     EIENKEVK"
     gene            5814..6041
                     /locus_tag="KR294_000934"
     CDS             5814..6041
                     /locus_tag="KR294_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239040.1"
                     /translation="MVELVKEFDLQTIKVGNAVKVNCKRFGFEIDCIVVVATEKELNL
                     AYFDEGRGCMEYQALITEDIQDGDYEIKILS"
     gene            6139..6453
                     /locus_tag="KR294_000935"
     CDS             6139..6453
                     /locus_tag="KR294_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239041.1"
                     /translation="MESLKRIKKMVQKQLVLAELEINKNSKLYEELENKDRGLIDDIH
                     MREYLREKVAWERVKYAIENILGGINLEIKSKEHEESEDYKIFQLILEELERDKPIDV
                     QI"
     gene            6537..7046
                     /locus_tag="KR294_000936"
     CDS             6537..7046
                     /locus_tag="KR294_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siphovirus Gp157 family protein"
                     /protein_id="HBH0239042.1"
                     /translation="MSTLYELTTDLLEIEEGLTETTGNETEKLEEIKEIIKQEIQNKN
                     TRIVSVILNIDSDINSIDSEIKRLQELKRVKKNTLDRLKSNIKDCMELLGTKKVETVL
                     GNISIRKSAGSLVIEDEEKIPAIYKTVEQVVKVDKNIIKDFIKKGHEVEGCRIEYGTT
                     LTIPKAKKE"
     gene            7056..7664
                     /locus_tag="KR294_000937"
     CDS             7056..7664
                     /locus_tag="KR294_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ERF family protein"
                     /protein_id="HBH0239043.1"
                     /translation="METNNVYIKLVNIQSTLKAPKSQFNSFGKYNYRSCEDILEGLKP
                     ILKEEKALVILDDNIVQIGNRFYVEATATLIDAETGEKVSTKALAREDETKKGMDLAQ
                     VTGSVSSYARKYALNGLFCIDDTKDSDATNKHGNEQKKKEVNESELNTLYSLGESIEK
                     DKNRVDSEVYKKFGKLAVDLTKQEYEKVLNGYKSILEKQKQE"
     gene            7674..8555
                     /locus_tag="KR294_000938"
     CDS             7674..8555
                     /locus_tag="KR294_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HBH0239044.1"
                     /translation="MGIIRVSKDKDNPYVVLNKTCLEDVKLSWQAKGLHSYLISKPDH
                     WKIYVNDLCKRSKNGRDATANILKELIENGYITRKPCRDSNTNKMLGGYDYEVYEIPL
                     ENPQKLKSRKTDFPETGFPGNRVSRKPENTEVVSNDFKVNNDITTIVINEQSNKDKTT
                     YIKKYFEKYIGVITPNNFIELMSYLDDGMEADVIIRAVDEAVGSGVKNYKYVKTILNN
                     WIEAGVKTVLELTEYQNEFERKKKSKQEKKQSNSKTVNTHNVNKNKFANFNQTFTQYE
                     EKELDEIIKKSQKEKFK"
     gene            8616..8789
                     /locus_tag="KR294_000939"
     CDS             8616..8789
                     /locus_tag="KR294_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="resolvase"
                     /protein_id="HBH0239045.1"
                     /translation="MARIYAQRSGSLNEQDRLELLRLLGKAGYTVKVAREKQNSKTTY
                     TYFVEYTEEQEEK"
     gene            8805..9212
                     /locus_tag="KR294_000940"
     CDS             8805..9212
                     /locus_tag="KR294_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBH0239046.1"
                     /translation="MNTITLVGRLVADAELKYLPNSGTPKITFSMAVDRRFKDKNGNK
                     ITDFIQCEQLGKHVENLVQYLVKGKPIYAVGELNIYNYKDENGCWKSITKVNVNALEL
                     LSSKNDNNAKQEYVPPGLDPQGFQAIDDDDIPF"
     gene            9286..9480
                     /locus_tag="KR294_000941"
                     /pseudo
     CDS             9286..9480
                     /locus_tag="KR294_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861747.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            9532..9789
                     /locus_tag="KR294_000942"
     CDS             9532..9789
                     /locus_tag="KR294_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239047.1"
                     /translation="MIIIRSQDKTDLVKADWINVDKECVYAMFGDMDNFKKIGEYEDE
                     KRAIQVLDNIQRFIEGGTRTDSIDSYKVRSYRNRIFQMPVK"
     gene            9803..10168
                     /locus_tag="KR294_000943"
     CDS             9803..10168
                     /locus_tag="KR294_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239048.1"
                     /translation="MLKVEKYFSGSLGTNIIDDDPTCRNYLALYCCVHGVRKNGELIF
                     PTCEKMLIEFNVDKNRKKKKKGSKVKLINAKTGEEKIFDSIDSAACFLRLQSQAVYQT
                     IKKKTKTRSGWKAEYIEEE"
     gene            10286..10621
                     /locus_tag="KR294_000944"
     CDS             10286..10621
                     /locus_tag="KR294_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015981539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239049.1"
                     /translation="MNILASVILVIGSFIAGRVYEYRLNLNENDEADSKVLLDVFNEI
                     SVLREENKSLKEKLQEKELLFINRLIDFLHDKKICECCIYDCKIDDIEYDCEDGIKKW
                     LDSEELIFE"
     gene            10729..11802
                     /locus_tag="KR294_000945"
     CDS             10729..11802
                     /locus_tag="KR294_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HBH0239050.1"
                     /translation="MLTFLDLFAGIGGFRLGMEKAGHKCLGHCEYDKFANLSYNAMHK
                     PKEDEWFERDIREIRTENIPRADVWCFGFPCQDISVAGKQFGFRGERSSLFFTVTKLI
                     RELKEEDRPKYLLIENVKNLLSVNGGFDFLKVLVELDEIGYDAEWQVLNSKNFGVPQN
                     RERIFIVGHFRGRSTRKVFPIERKSRKNLEQLNNPTHSTNRIYDAVGIARCIRSQAGG
                     GGAKTGLYFIDLNKNSKVTINARCLKAKYNAGVTNRNCDNSGVLVNAVLTPDRVNKRQ
                     NGRRIKESGETMFTLTAQDKHGILKNGDIRRLTPKECFRLQGFPDKYYERAASVCSDS
                     QLYKQAGNAVTANVVYEIAKRMG"
     gene            11882..12091
                     /locus_tag="KR294_000946"
     CDS             11882..12091
                     /locus_tag="KR294_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239051.1"
                     /translation="MYEYILRWQIGLSLENRKIHYTYGSKEALRKKAKALAKDENIVL
                     ITIDKVDEVIKNTISEKIIERFENL"
     gene            12103..13107
                     /locus_tag="KR294_000947"
     CDS             12103..13107
                     /locus_tag="KR294_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HBH0239052.1"
                     /translation="MIIHKFIIHVLDKNSDTPILNDFEGRVNQDMVLFFQKKISKVSR
                     DNDIRTAVFNNYSNNLIKKCCEQIIYDESSFLNNSKEIAAYLFDVMKLNATLESCDLA
                     ICLYSQKDEKKVAILKLDYNNSYTHSIEFKDDKFNIQMSKNEINIQETKTVKIAALVG
                     LSGMNDKYHLRVLDKDAEKEEANSKFVTEFLNATKIKDDKYKTKKFKNTAENWITNAL
                     SNDIKQAEDVRSILNYTLREKHEIDINDFVDKTIKDDKLKDSFKEHMEEKGLVEGFSI
                     DKKWVDKKLKKRNIKTDNGFEIKGNLTDFEDPMKYTVRQNQNGSIDIVIKNVTFYEEK
                     "
     gene            13189..13518
                     /locus_tag="KR294_000948"
     CDS             13189..13518
                     /locus_tag="KR294_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239053.1"
                     /translation="MKIFLLTILLIIICILANYVKNRIYKKSINNLKYKYSVGEKIIY
                     HQINCYYNRMVGCEILEKCYSTKFRKRNTPLYKVKAYVGDNDTTWVIPEWRIECLATT
                     YGEFPKY"
     gene            13555..13926
                     /locus_tag="KR294_000949"
     CDS             13555..13926
                     /locus_tag="KR294_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239054.1"
                     /translation="MFNIYKVKIKTKRTLEQVRNQSVDFEYSEKGLKNTLKYYNLIDD
                     LKVIVVKFGDEYCLANYNEEDRKIIMEAHYLLEQDEYTGCYINEYERFKKDWENGNCD
                     GEACMVFSDDEIEIIEKLREG"
     gene            13929..14111
                     /locus_tag="KR294_000950"
     CDS             13929..14111
                     /locus_tag="KR294_000950"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239055.1"
                     /translation="MNKRIKMKKRLIHKKCDERCVNYDFVISNNLITCNVCIGCKYKE
                     NMDKVCEENYKKLRSK"
     gene            14191..14532
                     /locus_tag="KR294_000951"
     CDS             14191..14532
                     /locus_tag="KR294_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor-like protein"
                     /protein_id="HBH0239056.1"
                     /translation="MANIYCENYNCKNYFEDMCMLERIEINNFKECESYLEGKNELYE
                     LENGYTIHPKDLKMVKSKDYSVEVTHIPTGITVKCRSTNSILKNKNKCLEVLEEELTK
                     INSHLELEDLR"
     gene            14658..15065
                     /locus_tag="KR294_000952"
     CDS             14658..15065
                     /locus_tag="KR294_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HBH0239057.1"
                     /translation="MKVFLVIDGEPVGKERPRMNTYAKRTYTPNKTKNYEDLIKWLYQ
                     SKVKYYFEGYIKMTLRCYYSIAKSNSKKVKEQKRNNVLRPSKKPDIDNVIKVVADSLN
                     EIAYKDDTQIVEVVASKYYSDNPRVEVILEDVI"
     gene            15167..16015
                     /locus_tag="KR294_000953"
     CDS             15167..16015
                     /locus_tag="KR294_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6C domain-containing protein"
                     /protein_id="HBH0239058.1"
                     /translation="MNENINKEITVLGTLEIEGMKFHNIEGGFGEHKKAMLVKDIAEI
                     HNRESRQINELINKNRKRFKDGKDILDLLGVGLDDTKIKELGFTQQSINSYRGLKNKG
                     LLSGIYILSERGYAKLLKILEDDIAWELYEKLVDGYFSMRKELNNPLLSASKELQAIF
                     MLDKKQEVLETKIENVNEKLENFMDDAPLFNIECESIVKEVKKVATKSLGGHGSKAYK
                     NKSLRGKVYNDIYHQIKREFGVDSYKAIKRCQLNKVLEIVNNYKLPIVFEEEIRLLNS
                     QLSIVS"
     gene            16118..16606
                     /locus_tag="KR294_000954"
     CDS             16118..16606
                     /locus_tag="KR294_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239059.1"
                     /translation="MDNNINKKELFKKVEGRLHHYKFLSAEIKNLELDIESRENEIFG
                     CKAVGYDEKVSPTYAFNSTVENEIIKKERDITRLKKLKKDKEIEKKKIENALTCLDIR
                     EEHFFKLFYNSRMKNSMVYISLEMNSDRKTCRCVRERLVYKVMDMLYPRIKENELPLF
                     KN"
     gene            17353..17526
                     /locus_tag="KR294_000955"
     CDS             17353..17526
                     /locus_tag="KR294_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239060.1"
                     /translation="MATKSILKNVDVRKKAFGRNLVSALENAKNKQEKEVVLSKKCSE
                     VPKDKIKDIFGRF"
     gene            17526..18137
                     /locus_tag="KR294_000956"
     CDS             17526..18137
                     /locus_tag="KR294_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HBH0239061.1"
                     /translation="MSGYLIVNLSNMLGELEEEEVKKILSSFSCPLNKDVEEFLKNKA
                     IEFSKQGLASTHLVLTSYKGKPVIVGYFTLANKYFTIKRKTLSNSLARKIVKFGQYNE
                     ELRRYIIGAPLIGQIGKNYSNNYNKLIKGDELLKIACDKIKAVQLDMGGKIVYLECED
                     KPKLIEFYKDNGFVDFGKRSLDKDETDSLDGDYLVQMLKYLKK"
     gene            18214..18402
                     /locus_tag="KR294_000957"
     CDS             18214..18402
                     /locus_tag="KR294_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239062.1"
                     /translation="MEIKKNTQDVVSERKNSLDSEFKIPASGVCYMAEFIKESREIIK
                     ELDKHFESCLDVLSKARL"
     gene            complement(18382..18699)
                     /locus_tag="KR294_000958"
     CDS             complement(18382..18699)
                     /locus_tag="KR294_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239063.1"
                     /translation="MSKNIDIRNLKQFQKKIERMEQNLKPDFDKIRTIILSKKFMNQH
                     TNFDSFDELLAFGNYIVNSEEDFLAIPDNEFDLFIVKNTDFPDWQTMLDSAYSKYLES
                     CLR"
     gene            18823..19050
                     /locus_tag="KR294_000959"
     CDS             18823..19050
                     /locus_tag="KR294_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239064.1"
                     /translation="MGFEISGNLNFDSVIDDLKKEVENNPTIFTSQNVGNKFKEKCKI
                     CEKISEFEILEDGKVKCLECGTEFELNLKVE"
     gene            19120..19812
                     /locus_tag="KR294_000960"
     CDS             19120..19812
                     /locus_tag="KR294_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH0239065.1"
                     /translation="MQDVKEKVKQDYLKGMKQKEISSKYDISLNTLKSWIKRYNWASE
                     KKKGAPINKRGAPFSNKNSVGHGAPKENKNAEKFGFFSKYLPEETRELIQEISIKDKF
                     DILWEQITIQYAAIIRAQKIMYVKDKEEMIKELKKHESTENGEKIEYEFQFAWDRQAS
                     FLNAQSRAMSELRSLIKQYDEMIHKDWNLATEEQKTRVEKLKCEVDNLSKDDIGDDEL
                     KISVDYGDRNDS"
     gene            19790..21043
                     /locus_tag="KR294_000961"
     CDS             19790..21043
                     /locus_tag="KR294_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HBH0239066.1"
                     /translation="MVIEMIVRVNFNPDFKEANFTKKRYRAMKGSAGSGKSVNVAQDY
                     ILKLGDKKYQGANLLVVRKSEATHKYSTYAELTGAINRIYGKQADKYWKTTLNPLEIK
                     SKVTGNSIIFRGVNDAKQREKLKSINFSKGKLTWVWCEEATELMESDIDILDDRLRGI
                     LTNPNLYYQMTFTFNPVSATHWIKRKYFDYKNDDIFTHHSTYLQNRFIDEAYYRRMQM
                     RKEQDPEGYKVYGLGEWGETGGAILKNYVIHEFTTEFEYFDNMRLSQDFGFNHANVVL
                     RIGFKDGELYICNEIYVHEMDTSEIIKIANSIGLEKTLFMYCDSAEPDRIKMWKNAGY
                     KAKGVKKGPGSVKAQIDYLKQLRIHVHPSCTNTIKEIQQWKWKQDERTGLYLDEPVEF
                     MDDAMAALRYSIDNKLKNNGISFLK"
     gene            21049..22488
                     /locus_tag="KR294_000962"
     CDS             21049..22488
                     /locus_tag="KR294_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBH0239067.1"
                     /translation="MLNIYISETDLIKVQLKKESTFNLVKVIEHYILKHRPEKYKQGE
                     EYYYGNTDVNNKRRYYLLDGAKVDDFTKVNNKAINNYHKLLVDQKVGYSVGNPIVFNA
                     DDDNLTKLLNDLLGEEFDDTITELYLNASNKGVEWLHPYINRKGEFKYVIIPAEEAIP
                     IWDSKRQRELVAFIRFYYIEDIDGNKIKRVEYYTENDVTYFVERGNSFVQEFLYDEYG
                     KMTDIQEGHFRINNKEQGWGKVPFISFKNNEKCVSDLTFYKSLIDIYDNNISTLADNL
                     DEIQEVIYVLKEYPGTSLQEFIDNIRYYKSIKVDGGGGVDKLEINIPVEAKKELLDRL
                     EKNIIIFGQGVNPESQNTGDKSGVALKFLYSLLDLKCSKTEKKFKKAIRELLWFVCEY
                     LKISGSKSYDYKTVQITFNHSMIINEAEKIDMAAKSTGIVSDETIVSNHPWVEDVNDE
                     LERLKKQEDTQKEYDDLIPNNQDGVIDET"
     gene            22478..23875
                     /locus_tag="KR294_000963"
     CDS             22478..23875
                     /locus_tag="KR294_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HBH0239068.1"
                     /translation="MKHKDYWRKRFEQLEEAQNNKSVKYYLELEKQYKLAMNSIEKDI
                     LAWYNRFAKNEGISLLEAKKLLNTRELEEFKWSVEEYIRHGKENAINQKWMKELENAS
                     ARVHITRLEALKLQIQQQVEVLYGNELDGIDKLMRHIYTSGYYHAAFNVQQGVNVGWS
                     LMNLDTNRINKVISKPWTSDGLNFSERIWGKHRPALINELHTKLTQSIIRGENPKNLV
                     NDFSKRFNVSKSQAKNLIMTESAFFASASRKDCFNDLDVEKYEIIATLDLKTSNICRE
                     LDGKVFDMKDYQVGVTAPPFHCRCRTTTAPWFEDEEGYRAAKGEDGKTYYVPSSMKYN
                     EWYEKYVKHNSILEIKNSAIIDSIKEDIKNGKYNLNIHDGKQGKHLKEHNNYIEGRSY
                     LTITKEEAQELVNKHAGNGIIKFNRSGEWDKKELIEVDKNIGVNVNNITGEKTLTNKF
                     KIHYSKTGTHIVPAL"
     gene            23890..24090
                     /locus_tag="KR294_000964"
     CDS             23890..24090
                     /locus_tag="KR294_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239069.1"
                     /translation="MKLWEYVGKNVQITCVDKQIIRGKCDGYTQALDNEPEIASISIA
                     RDGYGIEVYENEIESIENINKE"
     gene            24156..24719
                     /locus_tag="KR294_000965"
     CDS             24156..24719
                     /locus_tag="KR294_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage scaffolding protein"
                     /protein_id="HBH0239070.1"
                     /translation="MDWLKELLEGIKIEDNKIDVASLQKSIEKKIKETTITQEDYTNL
                     ETQLNTANETIKKFEGGMTKEDVENLKTTYETDKKTLEETYKKEIEEKDFNYWLNDAF
                     KSIKCRDEIALKAHLDIEALRNSKDRQKAFEEQINPLKQDKDYLFNATLEGEEPKIDT
                     ITPGQEPKINDFGFNFTGVRPHENNNK"
     gene            24731..25630
                     /locus_tag="KR294_000966"
     CDS             24731..25630
                     /locus_tag="KR294_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsid protein"
                     /protein_id="HBH0239071.1"
                     /translation="MAALNYAKEYSNVLAQAYPYTLNFGDLYATPNNGRYRWTGSKTI
                     EIPTISTTGRVDSNRDTIAVAQRNYDNAWEPKVLTNQRKWSTLVHPADINQTNYVASI
                     GNITKVYNEEQKFPEMDAYCISKIYADWTALGNTADTTVLTTTNVLEVFDKLMEKMTE
                     ARVPENGRILYVTPVVNTLIKNAKEIQRTVNIKDAGTSLNRQTTDIDTVKIIKVPSNL
                     MKTAYDFTTGWKVGAGAKQIFMSLVHPSAIITPVSYQFSKLDEPTAVTEGKYFYFEES
                     FEDVFILNKKADAIQFVVEGAGA"
     gene            25630..25863
                     /locus_tag="KR294_000967"
     CDS             25630..25863
                     /locus_tag="KR294_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239072.1"
                     /translation="MAQVRKLNRILTIEECKIDDFLEMGYDLIDETGKVVRYGKSLNV
                     KDLIAENNILRSKVESLEEENKQLKEKNKLTKK"
     gene            25873..26274
                     /locus_tag="KR294_000968"
     CDS             25873..26274
                     /locus_tag="KR294_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239073.1"
                     /translation="MGNNIIDDIEKRLESFGYILKDGDKWLIDFVREKIENIIKLDCN
                     IKTMPIELKEIEADMIVGEFLFTKKNMGQLDIESINFEAVEKSISEGDTKVDFAIGSG
                     SQTPEQRFDSLIAYLTAYGKNKILTFRCLRW"
     gene            26268..26615
                     /locus_tag="KR294_000969"
     CDS             26268..26615
                     /locus_tag="KR294_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239074.1"
                     /translation="MVSKTRKAIEMLYRYKCTIVEYQPIKDPVTKRTNNKEVIVLENQ
                     PCKLSYKNIVSATEGKLAKLEQTIKLFISPDIEIKAGSKLIINDKEYVRSGESAIYPN
                     HQEIILELFKDKA"
     gene            26615..27040
                     /locus_tag="KR294_000970"
     CDS             26615..27040
                     /locus_tag="KR294_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HBH0239075.1"
                     /translation="MARWGSVDFREFKRVCKKMEKLTKIDLDKFCKDAARELAARLLG
                     KVIRRTPVDTGFLRQGWNGVAYARSLPVYKQGNNYIIEVVNPTEYASYVNFGHRTKDG
                     KGWVKGQHFLTISEMELQSQVDKIIEKKLLILLKGVFDA"
     gene            27033..27470
                     /locus_tag="KR294_000971"
     CDS             27033..27470
                     /locus_tag="KR294_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239076.1"
                     /translation="MLNNIIDGISVKLDKSFGEKYTIYSEDVEQGINEPCFFIVPLNP
                     SKTPYPSGRELKKNSFDVHYFPRSEAKNFEINEIAEMLLEELEYIEINGDLVRGTNMN
                     FEIIDNVLHFFVDYNYFTIKSNNADKMNTVELFGGLKRGDNFE"
     gene            27463..27639
                     /locus_tag="KR294_000972"
     CDS             27463..27639
                     /locus_tag="KR294_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239077.1"
                     /translation="MSKTLSKGTDYKFTKEQIVNSKKYVNRKDLLNAILKENELYSFS
                     EVEDRINKFMKGVS"
     gene            27640..28950
                     /locus_tag="KR294_000973"
     CDS             27640..28950
                     /locus_tag="KR294_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath family protein"
                     /protein_id="HBH0239078.1"
                     /translation="MALGGGTFVTQNKVLPGSYINFVSATRATSSLSDRGIVAMPLEL
                     DWGIDEEVFQVTSDDFEKYSTKYFGYDYTHEKLKGLRDLFKNIRLGYFYKLNKGVKAS
                     CSIATARCSGIRGNDLKVIVTTNIDDNAKFDVVTLLDNKKVDTQIAKVITELQDNDYV
                     TWKKEATLEATAGLTFTNGTNGEAVTGTEYQAFLDKIESYSFNALGCLATTAEIKSLF
                     VEFTKRMRDKVGAKFQTVLYKKNDADYEGVVSVENKIKDTGLLESSLIYWTTGAIAGC
                     DINKSNTNKRYDGEFDVDVNYTQIHLEEALKTGKFIFHKVGDEVHVLEDINTFVSFTD
                     EKNDDFSSNQSVRVLDQIANDIATLFNTKYLGEVPNDKSGRISFWNDVVKHHEQLQNM
                     RAIEDFKADDVSVEPGSDKKTVVVSDAVKVISAMSKLYMTVSVS"
     gene            28972..29442
                     /locus_tag="KR294_000974"
     CDS             28972..29442
                     /locus_tag="KR294_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tube protein"
                     /protein_id="HBH0239079.1"
                     /translation="MAQQIKARDTISASKAECFVTIKGKRYNFMQAINLEAKMEKNKS
                     EIPILGSTTKGNKSTGSKYSGNATFYYNTSIFRELLYEYKETGEDIYFDIQITNEDPT
                     SSVGRQTIILEDCNMDSGIIAKFDADGEYLDEDMDFTFENWKLVEKFNIANGME"
     gene            29495..29752
                     /locus_tag="KR294_000975"
     CDS             29495..29752
                     /locus_tag="KR294_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239080.1"
                     /translation="MIKIKDKYEIKDSISFDYSNKRPLEERVSEMYKKAGKYLIDISD
                     KLATDTIDGSSLKPIIIKFEINEAGVATIEKQTKYLVMEVE"
     gene            29757..30197
                     /locus_tag="KR294_000976"
     CDS             29757..30197
                     /locus_tag="KR294_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBH0239081.1"
                     /translation="MGDLNAFLSQNAIKVENRKYVASERFIGEDGKAIEWELKAIDSD
                     RDRQLRKDSTIRVPVLNKKGKATGQYTSETDFNTYTLKLCVETVVFPDLHDAELQNSY
                     GVMGAEELLTTMLTPGEYTDLSSEVGEVNGFDRTFEDKVEEAKN"
     gene            30518..30679
                     /locus_tag="KR294_000977"
     CDS             30518..30679
                     /locus_tag="KR294_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239082.1"
                     /translation="MDNFLLSILASLIASLIGYIVCRCIKNVKSHSTRGKSKSGWELG
                     FKIKFRKFK"
     repeat_region   31420..31646
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=31486..31515
                     /rpt_unit_seq="agttttagattaactatatggaatgtaaat"
     repeat_region   32249..33135
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=32249..32277
                     /rpt_unit_seq="gttttagattaactatatggaatgtaaat"
     gene            33348..33536
                     /locus_tag="KR294_000978"
     CDS             33348..33536
                     /locus_tag="KR294_000978"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239083.1"
                     /translation="MNKIATKSRAEYMKNRRKDKRGFSVLLDKEKLDKFDEVLEEKNL
                     TKKEWLEEKIDEELEQKE"
     gene            33656..34477
                     /locus_tag="KR294_000979"
     CDS             33656..34477
                     /locus_tag="KR294_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin Bro"
                     /protein_id="HBH0239084.1"
                     /translation="MKNELMMFEEKKVEVLEYNGQVLFNPYDCGRCLELSDSAIRNHL
                     SKMNDTQAVLLKNSNVLDKDFRKLHNTGEKFLTESGVYKLIFKSKKEEAERFQDWISD
                     EVLPAIRQTGAYITNNADPDKLREKASEIEKLQLAYNSTSMLKELLDDAGFDNKSKLL
                     TAKTLYKKAGIDLPIEINEEEHYFDTKQIASKLKIYSKSNKPAQLAVCEIIKKIKLEE
                     NEVKGVWETNGSWTGTVNKYTKSVIDKVRTWIEENNRPTKIAGEKKNFHVVYKIE"
     gene            34537..34707
                     /locus_tag="KR294_000980"
     CDS             34537..34707
                     /locus_tag="KR294_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239085.1"
                     /translation="MRESLLNKYNLKTDEDVEYFVKLANALYELKLNSEEKFQEYAEI
                     LRGILREQEERK"
     gene            complement(34997..35209)
                     /locus_tag="KR294_000981"
     CDS             complement(34997..35209)
                     /locus_tag="KR294_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010249169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0239086.1"
                     /translation="MSIKFFKLIDLLNRRGITKEELRLKIGASSTTIAKLSSNKNVSL
                     DVIDKICKALNCQPGDIMEYEDDEKL"
     gene            35487..35831
                     /locus_tag="KR294_000982"
                     /pseudo
     CDS             35487..35831
                     /locus_tag="KR294_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012103644.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6N domain-containing protein"
     gene            35913..36266
                     /locus_tag="KR294_000983"
     CDS             35913..36266
                     /locus_tag="KR294_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239087.1"
                     /translation="MQFLVAKTFFKKAGVDIPLEIEEKEHFYDTKQIARKLGLYTMSN
                     KPAFQAVKQIIRKLDIKEDETKTVLETNGSWTGTVTKYSNKVTEKVKVWLKENNNPIS
                     IKGDKKNYYILYKNN"
     gene            36299..36457
                     /locus_tag="KR294_000984"
     CDS             36299..36457
                     /locus_tag="KR294_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239088.1"
                     /translation="MYENLLDMDRIELIKELGSIFEKMKNENPDKFYRFVSLVKEECR
                     KKEKKENK"
     gene            36945..37727
                     /locus_tag="KR294_000985"
     CDS             36945..37727
                     /locus_tag="KR294_000985"
                     /inference="COORDINATES: protein motif:HMM:NF021378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHOCT domain-containing protein"
                     /protein_id="HBH0239089.1"
                     /translation="MGLFGGKEPCSICGGKGKNKVLENEYLCNNCFINFTIFSRERLK
                     ATSAMQVLADHEGIRKFINFSKTNRELLAKFVETNRINKFVSIDEDNNFIKISDIRKG
                     GDVIENVYATDEIMQFELLEDGESIASGGLGRAVVGGALFGATGAIVGGITGKKTTRK
                     VVDTFKIKITFNNINNPLEYVNLINAKTKTNSSIYQNACNEAQEILSVLSIIIKNNDK
                     ADNEQSKTSDSIEQVKGLKELLDLGAITEEEFNTKKKELLNL"
     gene            37794..40145
                     /locus_tag="KR294_000986"
     CDS             37794..40145
                     /locus_tag="KR294_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HBH0239090.1"
                     /translation="MATIQTSIRIFDGMTPAFRNMTNAINTTINSFDRLQQRLHNPLN
                     AGGIQISQQSLNNIENILTRIEQNIEKADEQQRRFNEDINKGVSNTDRLLGSVKKIAG
                     AYMGLKTIGGLGSLSDQMTSTNARLAMTNDGQLSDGGLNKMIFQSAERSRASYLDTAQ
                     IVSRIGMNAGSAFSSTREIVSFAEQLNKKFIIAGASTQEMSSALLQLTQGLGSGVLRG
                     EELNAVFESAPNIIRSIADYLDVDIGKIRGMASEGMLTADIVKNSLLAAAEQTNTEFE
                     KMPLTIGQIFTSIKNNAIMIFGAIQKKIEDTVSSRGFRTFIVNITDAIYVLGNVGYSV
                     FNGLIDLFSSPAFQGFFNLMIVGVSMITQGLGWIITQALSVANVFAQNWSIISPVIYG
                     IVGAFIAYKVIIYSVLIAQTIYTAITFTQCFVTALLSGELYVATKAMLINKLMTLGVS
                     RANVTLCVTMIMVVATIALVIAAIFVGVAIFNHFAGASISATGVVVGAFYFLGACIYD
                     VFAGAWNIVMAFAEFFVNSFNIVIYNVQMLFYKFQNFVIDSMGDVGGSFDNCATALAN
                     AFVSAANIAIKGINGVIKALNLIPGVNINTLGSLDKIDSFVKQYKDYQKTLKEPIKPQ
                     DWKAPYAEIKNPFDSYKKGYEVGQNLENKLKDAFDINKIAEKAKKDLRLDDLWDKKYG
                     LGDGLGSAGLNSPLGDAAKGAKDTAGNTAKMAKTMDKSQEDLKYLRDIAEQEVINKYT
                     GVNIKIDMNNTNNISKDTDLDGIVNVLTEKLNDAMVVSAEGVV"
     gene            40161..40856
                     /locus_tag="KR294_000987"
     CDS             40161..40856
                     /locus_tag="KR294_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBH0239091.1"
                     /translation="MAYDFYLDGVQLPITPGKLEIKTTNKNKTVDLINDGEVNILKTP
                     GLSEISFEAEFTHNKLPFCRGQFRDVQFFLSKLELLKTDCKPFQFIVSREMGGKVLFN
                     TNIKVSLEEYAISEDADNGSDTKVAIKLKQYRDYSTKKLVPAQPKTTNETGRPNVKIE
                     PKRVDSVNAPNAKTYTVKAGDSLWSICQKQLGNGSLYKKVYELNKTMMDKANKGKKLS
                     KYTIYKGQVLRLV"
     gene            40849..42819
                     /locus_tag="KR294_000988"
     CDS             40849..42819
                     /locus_tag="KR294_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBH0239092.1"
                     /translation="MSDDLVLANDRDIRLVIAHWEDFYEPVVLDGITWEIERRGTPSK
                     LEFTIVMDDILEFCEGNSVRLYYKGVGIFYGYIFQKKRDKENHIKIVAYDQLRYFKNK
                     DTYVYSNKTASELVKMLAKDFKLKYNVIEDTKYKISRVEENKTLFDMVLTALDDTLRE
                     KKEMYVLYDDFGRITLKNVASMKLDTVMNNDVIEDFDYNSSIDSDTYTKIKLVRDNEE
                     TGKRDVYIAQDSTHMRSWGILQLFDTVDKNMSEAEIKQKCDILLKLYNKKTKSLSLKN
                     VLGDIRVRAGCLVPVFLSLGDIDLQNYMLVEKVKHTFENNSHFMDLTLVDGDEFASYS
                     SSSYSSGNTNNKNEKQNGPAQSTTSKEDTDMANKINKLLKGKLSNTGNIFVKYSNAYK
                     VNPALMAAISMHESARGTSNIANTKNNFFGMKKNGDYMSFSSVDEGIKRGISNLSRNY
                     IHIGRKTLESIRNKYSSSSDKEWVKCVGAFYKQITGSTYNSNSAGTGVGSNEEAEKNL
                     KDLTYQVQNNNSNTSTNNNNKVSKVIQEAKNQLGKPYKWGGNGPKSFDCSGLMVWAFK
                     RGAGINLKRVSADQSKDSRGKLLCNINDVKAGDLVFFAYNKGKGNVHHVGLYIGNDQY
                     IHAPQTGDVVKISSLSGRQKKKHDFARARRFF"
     gene            42833..43093
                     /locus_tag="KR294_000989"
     CDS             42833..43093
                     /locus_tag="KR294_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2577 domain-containing protein"
                     /protein_id="HBH0239093.1"
                     /translation="MSQELLQIIKKAAMDAVETSNPMQIAFGTIESVNPLIVKIEQKA
                     SFEEFFLIQTETFKRYTDKKIGDKLVLIRMQGGQQYLILDRM"
     gene            43098..43517
                     /locus_tag="KR294_000990"
     CDS             43098..43517
                     /locus_tag="KR294_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2634 domain-containing protein"
                     /protein_id="HBH0239094.1"
                     /translation="MLPTDNIDYDIEDVSIINFDVRQEPSKTFKLNIEKNRVDGICDD
                     VEALKQTIFLILNTERYEHLIYSRNYGVELNDLIGEPISYVIPELERRITEALIQDDR
                     IENIDNFEFQNIKGKVQCRFSVHTKYGNIKAEKVVSV"
     gene            43518..44567
                     /locus_tag="KR294_000991"
     CDS             43518..44567
                     /locus_tag="KR294_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HBH0239095.1"
                     /translation="MFELMTFENIIKRMLDSVPDTFDKREGSIIYNALAPVAIELTET
                     YIAMDELLDQTFVDTASYYYLEKRCKERGITPLEATNTIAKGVFNIDIPIDSRFNLGE
                     YNYVAIERISEGIYKMKCETAGPIFELGQLIPIEYIDKLETAELTEILINGEDEESED
                     SLRQRYYDSLNSQSFGGNMQNYKDEVNKIQDVGGVKVYPVWDGGGTVKLVIINSNFKV
                     PSEDLVNLVQEEIDPIGHQGQGLGLAPIGHKVTVTGVVSTTINISAEITYKNGYTWEN
                     IKSIAEEAIDDYLNELNMSWEDEENLIVRISQIETRLLSIDGVLDIANTMINEVKSNL
                     TINSNSIVVRGEVVG"
     gene            44560..45177
                     /locus_tag="KR294_000992"
     CDS             44560..45177
                     /locus_tag="KR294_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmfQ family protein"
                     /protein_id="HBH0239096.1"
                     /translation="MDKEINLINYLPQILQDKEEYIKVFNVGNKEIKILHDKLKDLSN
                     DQFLEDLTISGIKRWEKIMSITPKSNESLEDRRFRIFSKYISKLPYSERFLRNWLDSI
                     VGEGNYELTINNATYNIHLESDARNQDWFEEVHSFVSNIKPCNMTLDYTRVLISKDNY
                     MNFGITTLMGQEITIYPWSPPDIETYGEIDVLTGNGVGYQEITIF"
     gene            45189..46214
                     /locus_tag="KR294_000993"
     CDS             45189..46214
                     /locus_tag="KR294_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBH0239097.1"
                     /translation="MAIDKSYYTIITDVGKAKIANASVTGNKVGFVKIQLGDGGGSEY
                     TPTESQTALKNVVWEGNIGNTTTDETAPNCIILESLIPSSVGGFMIREIGYLDDENNL
                     IAISKYKECYKPSIEQGAVVDMKVKTVLIVSNVNNIELKIDPTIIFATLKDIQDLETK
                     IGTVNTKIDTTKTELTNNLETAKTELNTRIDTENEKQNIKIDQLIAGGSNVASTQTIT
                     IDDWVEDAENGFKATVTHSLLTQRIVVNIIDVTTKENVVTNFKIIDDNSIEIRSEVKA
                     ELNVYVINGNAETHFINATVDDNRVSEMTTYSSKKIEDRLINIEEKVNGGLSSIATSV
                     NELITYC"
     gene            46229..47911
                     /locus_tag="KR294_000994"
     CDS             46229..47911
                     /locus_tag="KR294_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239098.1"
                     /translation="MQTEWNFGYNGSPQSVILKPGKYKFECWGSSGGINNSSWYTDAK
                     GGYSKGEITLKKQTTLYVYVGESGFASSSTSNNTKSGFNGGGKGYLNQQIMGTYYSMY
                     GGGATDIRLVGGAWDNEQGLLSRIIVAGGGGGSYYPSTGGAGGGLEGGTGYSSNDRYR
                     PGGTQYQGGIGRVNTENGSFGKGCSVKDSTGEGGGGGWFGGAGMNGVGAGGGGSSYVL
                     TKDSYKPTGYTPTSEYYFDNIVMTPGGNTAGAYGYAQITLLQSLPFLNISSYNSTQAT
                     FKADHTDPTLLTKIEYFIDDVLKETITTDLTEEKTINYTLEDNALHTLKIVVTDSNNA
                     TAEKAVSISKNIMPLPENVNLNDISTKLVEVNAGFKTGKTSIINTLALKNIEASLNNT
                     LVELSEKIKTSFDSSDASVQDLMNQLTQANNTISQLNSKYKVASGNSVVNYCTNTKGF
                     YFNSDYLFLFPGAIQINGLNFVPNIFFTTFELIDDGYFHKYFVFACRGIFTQDFVITA
                     HYYRLTSYLQDFKVGGEVLKLNERDVYMDNRGIQLPCSRQGSSFKWQAIKFI"
     gene            47928..48221
                     /locus_tag="KR294_000995"
     CDS             47928..48221
                     /locus_tag="KR294_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239099.1"
                     /translation="MDRANRIIYDQTGKILLQTGEATGDILEHDTITELHYIDVEYGS
                     IDYTRNRIIGINIETKEPILEEIPVFISEEEKRIQELENQILLNENKKVGGIL"
     gene            48221..48403
                     /locus_tag="KR294_000996"
     CDS             48221..48403
                     /locus_tag="KR294_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239100.1"
                     /translation="MNINNVVVRILAERILNGGLNPLKNREFELDDVTNAEYRKAVED
                     YIIRESGVVEEAEPTI"
     gene            48436..49668
                     /locus_tag="KR294_000997"
     CDS             48436..49668
                     /locus_tag="KR294_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239101.1"
                     /translation="MTFKELVNKVRNLVLEAKNVTIEDTENNFTSDNVEGALKEVFQN
                     GVNAKSNVVTALNSKGADVTTSDTWEEIKNKIDIKEGRLDLRETTLSNNYSYLVTNGA
                     IKYIERCSGNFKTFEYEEPYFYVIKETHLIKINAIDETVVFDITLANANFSCICVTQE
                     YLFISDNTKLYKINKITGIEVQSIEGAYYKLCTYGEFIYGVYGDETSSTLHKIRISDM
                     YIMLTKNLVSNGIYNFKGGKFVCNKNAIYATTEHSNSSSITTCHLSKINFDFAIAKDF
                     RIGGYLHMKNIKFLNDFVIVSDAERGIEIDSNKKSALVKYDANLNLIVYSDDNKYDNF
                     DIYNGYIYAIYSLSSSPFVKISLNTLKHIDSYRKLTETYPNAGMFVINDIVFFISSGI
                     FRNILSKKVYSDEKGESL"
     gene            49665..49964
                     /locus_tag="KR294_000998"
     CDS             49665..49964
                     /locus_tag="KR294_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239102.1"
                     /translation="MIYLGNLMDTEEQNIKYVGMIHYEPNLLSEENLKQGILIESLPT
                     QKYAENKEAKLFINIDTKEVFYRYTDIKSNIEDKVNSTEQTIADLTFQLMSNGVI"
     gene            49966..50103
                     /locus_tag="KR294_000999"
     CDS             49966..50103
                     /locus_tag="KR294_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HBH0239103.1"
                     /translation="MNWYKIIADFYNNGNWTKEQVKTAVEKNKITASEYKEITGEDYI
                     A"
     gene            50135..50365
                     /locus_tag="KR294_001000"
     CDS             50135..50365
                     /locus_tag="KR294_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin XhlA family protein"
                     /protein_id="HBH0239104.1"
                     /translation="MNEELFEADLKRHETRINKHGEEIDELKIANIESKAELKALCEN
                     LNSLTSMLKWLIGTMITTLIGFFIFAIQRGIF"
     gene            50381..50638
                     /locus_tag="KR294_001001"
     CDS             50381..50638
                     /locus_tag="KR294_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HBH0239105.1"
                     /translation="MDNLISFIPEQLLILVAALSIIGKGCKKYKQLDNKYIPIILLVL
                     GIGFSIWMLGLSPNAVLQGIICWGISIGINQTYKQLKEENK"
     gene            50638..51450
                     /locus_tag="KR294_001002"
     CDS             50638..51450
                     /locus_tag="KR294_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBH0239106.1"
                     /translation="MKICITVGHSILKSGACTSADGVVNEYQYNKSLAPVLADTFRKE
                     GHKVDVIICPEKQFKTKNEEKSYKIPRVNSGGYDLLIELHLNASNGQGKGSEVLYYSN
                     KGLEYATRICDKLGTVFKNRGAKLDKRLYILNSSKPTAVLIESFFCDNKEDYDKAKKL
                     GHEGIAKLIVEGVLNKNINNEGVKQMYKHTIVYDGEVDKISATVVGWGYNDGKILICD
                     IKDYVPGQTQNLYVVGGGACEKISSITKEKFIMIKGNDRFDTLYKALDFINR"
     gene            51531..51893
                     /locus_tag="KR294_001003"
     CDS             51531..51893
                     /locus_tag="KR294_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239107.1"
                     /translation="MEDLCMDALVYERFVRAAFSIKLNNLINRSEDLGGLAEADIFRA
                     ANNLHELNEIKIGTGYAIAIFNNEILESCNVSDNDSNRMIELFDRSLIATSREEILDI
                     IREYETYRGRYLTFNWKR"
     gene            52059..52577
                     /locus_tag="KR294_001004"
     CDS             52059..52577
                     /locus_tag="KR294_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239108.1"
                     /translation="MDKKIDIAKFIVNRIDYYIEKSDNKASFLLLLNSAIIGFLFSGK
                     EKIMNHLSISNIRCLEMLFYIVILCIFVISIYFSIMVLKPRNSKIENEYKSIFYYKEI
                     ASLNNEQYKEAFENAFKDEENLINDALVQIKELSLICDKKMYNVKKSVEAFILGGIIL
                     FIYILVVVFNAI"
     gene            complement(52641..>53376)
                     /locus_tag="KR294_001005"
     CDS             complement(52641..>53376)
                     /locus_tag="KR294_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239109.1"
                     /translation="EFDDSFSFDEIEENELVREYFFNKKGESKLLIDSFMFNSVDKAL
                     DKILIDRNLSDKIEKIGDVISKTNPSYDKNTIDKDYIKVDLMELHCVAVCYNKSTSKI
                     LIAKRSDNRNNNASKWEFGCAKASLETSIINTIKDEYEKDFNINIEPITDCTRKDDCQ
                     PIPLAIYQVKKSDGLHKGIITLAEIINDYDISKFEPTSKHNELAWIGEDELEDFNENT
                     VPDFKETLKLAFKKLNENQLQESTNM"
BASE COUNT        21786 a         5568 c         9860 g        16162 t
ORIGIN      
        1 ttgaaaaaga ggtggttgta actattttta agaacgtatg tttcgtggaa ttaataaata
       61 aaatatttta taggggatga tatatttgaa taagacgaaa tattatgata ttttaaagtt
      121 aaacttatta atgaaaaagt tgaaagaatt ggataaaaat aaaatcaatg aatataaaat
      181 aaaagtgaaa gaaatacata aaatcaataa aaaagaggaa tgattcctct tttttattat
      241 attcattttc agaaataaac tattttttat ttttttcgtc tagtaaaaat aattctgcaa
      301 cttttaatgc tttttctctt gcgtctgggc ttagctcgct aaatatatta aaaacttctt
      361 tcatatcttc gtcaagatac atattctcaa taagctcctt ttctgtttta aaattttcag
      421 catcataatc tttttcgttt ttatttataa ataagctatt tctaacatca gttcttccta
      481 ataaataatc tgtagacaca tcaaaatagt ttgcatattc ttctattgta cttttcttag
      541 gttctcttaa accattttct atccttgata gtgtagattt gtttatatgt aaatcctcgc
      601 ttaatttgtc tagcgagatg cctttttctt ctctcaattc ttttatccta ttcaatttgc
      661 acaacccctt tttatattaa ttccaaaata gcaactttta tttatattat agcaacaaaa
      721 ttaattatta caattttttt tgctaaaaaa gcaacaaaag tattgactat aatcacaaaa
      781 cttgatatta tataaatatg aagttgccaa aatagcaaaa aggaagtgat ttaatgtact
      841 taaatagatt agaaggattg atgaaggaaa atagacacac ccaaaaaaat gtggcagata
      901 tattaggtct tagctcatat ggttttagat taaaattaaa aggaaaaaac gaatttaaag
      961 caagtgaaat aaaaaagata tctaaattat ataatgtatc tgcggattat tttttttcag
     1021 atgaagttgc taaaatagca ataaaagaag aaaggggcaa taaataatga agaatctaac
     1081 cataatcaag caaaataatc aatttttagt tgaaagtaga gaagtagcag aattaataga
     1141 aaagaagcac gataatttat taagagatat aagaggatac aagaagattt tagaggactc
     1201 atcaaatttg aagagtcaag atttcttcat agaaagtact tatataaata ctcaaaataa
     1261 aattcaacct tgctacttat taactaaaaa aggttgtgac atggtagcta ataaaatgac
     1321 aggtgaaaag ggaattatat ttacagcgat ttatgtaact aagtttgaag aaatggagcg
     1381 agagttaaaa gaacaacaac ctaaattacc aactacatat aaagaagcat tgcaacagtt
     1441 attaatagaa gttgaagaaa aagaacaatt acaattagaa aatcaagaaa aagataaggt
     1501 aattcagtta cagcaaccaa aagtactgtt tgctgatgca gtttcaactt caaacaattc
     1561 tatattggtt ggagaacttg caaaacttat aaaacaaaat ggagtagata taggacaaaa
     1621 cagattattt gcctggatgc gagaaaatgg atatttaatt aagcgtaaag gtgaagatta
     1681 taatattcca acgcagaaaa gtatgaatct aagaataatg gaagttaaaa aaagagtaat
     1741 taataatcct gatggaagta ctaaagtaac tagaacagta aaaataactg gaaaaggtca
     1801 agtttatttt gttaataagt ttaaaagtag taaacaatta tcaatgttaa gttaaaacat
     1861 gacagcacct tgaaaactaa atataaaatt ttaaaaggag caagtatatg agaaataaag
     1921 aaaaagaaat aatcattaaa ggaattttaa taggaatttt ttatttttta tgaattgtat
     1981 ttagtaatac tttttttaaa taataaatag aaggtgtagg tgaaatacca actccccaaa
     2041 tcaaaataac actttggaag ttaaatatag aatattcaaa agaggtgatt agatggaaat
     2101 agagcaaaca aaaatacgcc tacttagagc gttaaaagaa gtaggcatat agtaattact
     2161 ctatatcatt ttctttttct aacattttgt cagctaaatc ctcaaccttg cttataaatt
     2221 tgatttggtt acgctcatca aatttatgta atagagataa gatttcctgt tcatttttgg
     2281 ttaagtttat attgtttgtt ttatcgcatg ttatgcccag caaaagataa tcagtagtaa
     2341 cattaaaata ttcagccatt ttaactattg catcagaaga aggtttgcct ttgccctttt
     2401 tccaatcact cacagaacta ttggaaattt ccaaatcatt tgttaattgc ttagctgtaa
     2461 tattattttt tttcattaaa tcaagtatac gattaatcac aaatttaacc tcttttctaa
     2521 aaaaaaatag gaaaattcca aactatgtat tgacactttg gaaaaatcca aatataatat
     2581 aactataata acaattactt acgacaacaa attgttatac aaacttaatt ttaccacaaa
     2641 taaacacact aataaagaag gtgataataa tgaataaaaa atgtttacca aaatggagca
     2701 aggaagttaa aaaagccatg atagatagag atttgaaact agatgattta tcagaggaat
     2761 tagggttatc aaaatatcat ctatcagcag taattaacaa tagactaaaa agtccaaatg
     2821 caaaagaagc aatttgcaag tatctaaaag taaaaggtta gttatagtat aacctttcaa
     2881 agaggtgatt tgaatgtcat atgagtacca aaatgtttat caaaaagcaa gagaaaatac
     2941 ctatttaaca caggaaaaag catcagagtt actagatata tcagtagaga gtttaagagc
     3001 atacgagaac gacaagagga taccaaacaa tcaaatagta gcaaagatgg tttctattta
     3061 taataataat ttactgggct atgagcatgt gagaaggact acagaagcag gagtaatgtt
     3121 cttaccaaag ctagaaatga aaagtctttc aagtataact ttgaaattac ataaagaaat
     3181 caaagattat ctaaaaaaag aagatgattt catagacata gttgaagatg atgtaataga
     3241 tgaagatgag gaagaagttt ggaatgatgt tatggaaaag ttagaaggta tatatgaagc
     3301 tattttaaaa ttaaaacttt caagaaatac aaaaatatca aaggaggtat aaacatgaaa
     3361 gatttaacaa tagtaaaggt taacaataaa ctaacaactg atagcagaga tatagctcta
     3421 atggttgaaa aagaacacaa gattttatta agagatataa gaaattatat aaaccagatg
     3481 gaagaagcta acaaaaacat gagtacagat ttgtacccat ctgattactt tattgaaaac
     3541 acttatttag atgactataa aagagaaaag ccatgttatg caataacaaa aataggttgt
     3601 gactttatag caaataaaat gacaggaata aagggtactg catttacagg gatatatacg
     3661 aaaaaatttg atgaaatgga aaaagcatta aaagaaaaac aacctaaact accaactaca
     3721 tacaaagaag cattgcaaca gttattaatc gaagttgaag aaaaagagca attacaatta
     3781 gaaaatcaag taatgaaacc aaaagcagat tactttgatg ctctagtaga aagaaacttg
     3841 ctaactaata taagagatac agcaaaagaa cttggagtca aagaaaaaac atttgtttta
     3901 tggttaatag agaagaaata ttgttacaga gatttaaaag gcaaaataaa accttactct
     3961 aacaagatgc agtattttga actgaaagaa tttacaacac catacggaca ttcagatact
     4021 caaacattaa taaatccaaa aggaagagaa gcatttagat tattacttat aaaggatgga
     4081 ctggtaaaag aaaaagaata tcaaataact ttattaggct aaaattgaaa gtactttgaa
     4141 aattaaagat tatggaggta gttacaatga gcgaagacat attttatggt ataaaaaata
     4201 ctcttgatga aatagcagag gttcaaatta aaaataaaca aggtgtgtta aaagaagttg
     4261 gaatgttaat aagtggtgag gacaattctt gtataacgca ttgtttagat gaagatttaa
     4321 ttaagtttta cataaaagaa gaggcagtat tgacaataga taaagatagt catttgttat
     4381 gtatgcttga tgctctattt tataactttc ttgataaata ataaatacag aatattcttg
     4441 aaatggtggt gaagaaattg ggtaatatat ctaactttaa tttagataaa caagaagata
     4501 aaagttttaa tgacctggat aatatatcaa tttgtttttc agaaggtatt cgtaaagttg
     4561 tagaaatgaa tttaaacaac tataaaaata aaatctcaaa atacttaaat gaaacttcga
     4621 aaatagaatt gttggaacca aaagaattaa caattgttat aagtaaaggt tatcccgatt
     4681 atcttatgtc tgttgaagaa gcaagtaaaa gattgaaaat agataaagta tttggatatg
     4741 agttaataaa aaatggactt ttgaagtcag ttgatatagg ggcaactaaa gtttctagtt
     4801 atgaattaga tgattttata actaggaatc aaggaaaaaa catcaaagaa atgcttagag
     4861 aaatgaaaga acttagagag ggggtgattt aattggaact agtaacatac agaaacaagc
     4921 ttgttttact aaaagatgga gaaaagattg caactataag tttaaaaagg aaatttctca
     4981 gcaacagact taaattaaaa ataagatagg agagataaat tgaaaataat ttataaaaac
     5041 aaagtttaca aagtagaaca agacaaaaag ttatttagaa ttacatacta tgatgagcag
     5101 agaggtagta agaagtttaa taaagagaag aaaataaaaa gaagtgtttt aacaagagat
     5161 atagagttag ttaacttgta tttaccagca catttaaaaa taaaataagc tataaataat
     5221 taaagaaaaa ggtgattaga tggaaataga acaagcaaca atacgcctgc ctagagaact
     5281 taaagacaag cttctaaaac aggcaaaagt taaaggatat acattaaaag atatgatagt
     5341 ttttattcta aaggattatc ttcaaaatat ttctcaagaa taaattcaat ttctctacct
     5401 atagaacgct tatctttttg agcaagttgt tcgattttct caaaaagaag tttattaatt
     5461 cttagtgtaa atcttttatc ctcttcacga gtataaatat ctttattaga catatttatc
     5521 attcctcaca taaaatttga cgtctttatg acactttaat aataaaataa tataaaagaa
     5581 aagtcaacaa aaatgcttga cgtcaaatat atgacatggt attattaaaa caagaaggga
     5641 gttgacgtca aatatatgac aaatgaaaga gttagattta catttagatt accagcacca
     5701 ttgcttgaaa aaattaaaaa tagagcatca atagaaggta gttcaatgaa ctcacttata
     5761 ttacacatac tttgggatta cataaaagaa atagaaaata aggaggtcaa ataatggttg
     5821 aattggtaaa agaatttgat ttacaaacaa ttaaagtagg aaatgcagta aaagtaaatt
     5881 gcaaaagatt tggttttgaa attgattgta tagtagtagt agcaacagaa aaagaattaa
     5941 atttagcata ctttgatgaa ggtagaggct gtatggagta tcaagcctta ataacagaag
     6001 atattcaaga tggtgattat gagattaaaa ttttatctta ggaggaaata aaatggctgc
     6061 tttaataatg gtaggtttat ttgcaatatg tttagtagga ttagttcaaa atagagatta
     6121 aattaagggg gattaattat ggaaagttta aaaagaataa aaaaaatggt tcaaaaacaa
     6181 ttagttttag ctgaattaga gataaacaaa aatagcaaac tttatgagga acttgaaaat
     6241 aaggatagag gtttaataga tgatatacac atgagagaat atctaagaga aaaagttgca
     6301 tgggaaagag taaaatatgc tattgaaaat attttaggtg gtataaattt agagattaaa
     6361 tcaaaggaac atgaagaaag tgaggattac aagatatttc aattaatttt agaagaactt
     6421 gaaagagata aacctataga tgttcagata taagaaaaga gccattgccg tggctcaatt
     6481 caaataaata tatcaaaatt taattaagct aattatagca caaacggagg gaaattatga
     6541 gtactttata tgaattaact acagatttat tagaaataga agaaggttta acagaaacaa
     6601 caggaaatga aactgaaaaa ctagaggaaa taaaagaaat aataaaacaa gagatacaaa
     6661 ataaaaacac taggatagtt tcagtaatat taaacattga cagtgatata aactctatag
     6721 attcagagat taaaagactg caagagttaa aaagggtcaa aaagaatact cttgatagat
     6781 taaaaagcaa tataaaagac tgtatggaat tacttggtac taaaaaagta gaaacagttt
     6841 taggaaatat aagtataaga aagtcagcag gtagcttagt catagaagat gaagaaaaga
     6901 tacctgctat atataaaaca gtagagcaag ttgtaaaagt agataagaat atcattaaag
     6961 actttattaa aaaaggtcat gaggttgaag gttgcaggat tgaatatgga actacactaa
     7021 caattccaaa agctaaaaaa gagtaggtga ggaccatgga aactaataat gtttatataa
     7081 aacttgtaaa tatacagagt actttaaaag ctcctaaaag tcaatttaat agctttggta
     7141 aatacaacta taggagttgt gaggatatac tagaaggttt aaaacctatt ctaaaggaag
     7201 aaaaagcatt agttatattg gatgataata ttgttcagat aggaaataga ttttatgtag
     7261 aagctacagc aactttaata gatgcagaaa caggagagaa agtatctaca aaggcattag
     7321 ctagagaaga tgaaactaaa aaaggtatgg atttagcaca agtaactgga agtgtatcaa
     7381 gttatgcaag aaagtacgct ttaaatggat tattttgtat tgatgataca aaagatagtg
     7441 atgcaacaaa taaacatgga aatgagcaga aaaaaaaaga agttaatgag agtgaattaa
     7501 atacactata ttcgctagga gaatctatag aaaaagataa aaatagagtt gatagtgaag
     7561 tatataagaa gtttggaaag ttagcagtag atttgactaa gcaagagtat gagaaagttt
     7621 taaatggata taagagcatt ttagagaagc aaaaacaaga gtaggtgata gtattgggga
     7681 ttataagagt aagcaaagac aaagataatc catatgtagt tttaaataaa acttgtttgg
     7741 aagatgtaaa attaagctgg caagcaaaag gtttacattc atatctgatt agtaagcccg
     7801 accactggaa aatctatgtt aatgaccttt gcaagagaag taaaaatgga agagatgcta
     7861 cagcaaatat tttaaaagaa cttatagaaa atggatatat aacaagaaaa ccttgtagag
     7921 attctaatac taataaaatg cttggagggt atgattatga agtatatgag ataccacttg
     7981 aaaatcctca gaagctaaaa tcccgaaaaa ctgatttccc ggaaaccgga tttcccggaa
     8041 accgggtttc tcggaaaccg gaaaacacgg aagtagtaag taatgacttt aaagtaaata
     8101 atgatattac tactattgtt attaatgaac aatccaataa agacaaaacc acctatataa
     8161 aaaaatactt tgaaaaatat ataggtgtga ttactcctaa taactttata gagttaatga
     8221 gttacttaga tgatggaatg gaagctgatg taataataag agctgttgat gaagctgtag
     8281 gcagtggagt taagaattat aagtatgtaa agacaatctt aaataattgg atagaagcag
     8341 gtgtaaaaac tgttttagaa cttacagaat atcagaatga atttgaaaga aagaaaaaga
     8401 gtaagcagga aaagaagcag tctaatagta aaactgtgaa tactcataat gtgaataaaa
     8461 ataagtttgc taacttcaat cagactttca ctcaatatga agaaaaagag ctagatgaga
     8521 ttattaaaaa gagtcagaag gaaaaattta aataaaatta aacttctagg aagtaaatat
     8581 caatatattg cttcctagaa aaggggaggt ataaaatggc gagaatatat gcacaaagaa
     8641 gtggttcttt aaatgaacaa gatagattgg agttattaag attacttggg aaagctggat
     8701 atacagtaaa ggttgctaga gagaagcaaa atagcaagac aacttatact tactttgttg
     8761 agtatacaga agaacaggaa gaaaaataga agggggctag ttaaatgaat acaataactt
     8821 tagttggaag attagttgca gatgcagaat tgaagtacct tccaaattca ggtactccaa
     8881 aaataacctt ttcaatggca gtagatagaa ggtttaaaga taaaaatgga aataaaataa
     8941 ctgattttat tcaatgcgag caattaggaa aacatgtaga gaatttagtg caatatcttg
     9001 ttaaaggtaa gcctatatat gctgttggag agttaaatat atataattac aaagatgaaa
     9061 atggttgctg gaaatctatt actaaggtta atgtaaatgc tttagaacta ctttctagta
     9121 aaaatgataa taatgctaaa caagaatatg taccaccagg attagaccca caaggttttc
     9181 aagcaataga tgatgacgat ataccttttt aattaagtta aataatctag ggagtaatta
     9241 tgcaatatta cttcctagga gttaaaaaat attggaggtt taagagtgaa atatgagtgt
     9301 gagaaagtgt tcttagaatg cgataaggga agttttgaga taaatgatac aagagctgaa
     9361 gaagtaacat tcgagggtac agaaatagac aatctgtttg agagagtaaa atatgaaggg
     9421 acttttacaa taatatctgg atgggattct ttattgagag atatattgtg gcttgaaatg
     9481 cggaaagtct taaaaattat aacaggaaaa atgatgatgg gggtattagg aatgataata
     9541 attagaagtc aagataaaac tgatttagta aaagctgatt ggataaatgt tgataaagaa
     9601 tgtgtatatg caatgtttgg agatatggat aactttaaaa agataggtga gtatgaggat
     9661 gaaaaaaggg ctatacaagt gctggataat atacaaagat ttattgaagg tggaactaga
     9721 acagattcta tagacagtta taaggttaga agttatagaa atagaatatt tcaaatgcca
     9781 gttaaatagg gaggttactg aaatgttaaa ggttgaaaaa tattttagtg gttctttagg
     9841 aacaaatatc atagatgatg accctacatg tagaaattac ttagcactat attgttgtgt
     9901 tcacggagta agaaaaaatg gagaacttat atttccaaca tgtgaaaaaa tgttaataga
     9961 gtttaatgtt gataaaaata gaaaaaagaa aaagaaaggt tcaaaggtaa agttgattaa
    10021 tgccaaaact ggtgaagaaa aaatatttga ttctatagat agtgcagcat gttttttaag
    10081 actacagagt caggcagttt accaaacaat taaaaagaaa actaaaacaa gaagtggctg
    10141 gaaagctgaa tatattgagg aggaataatg gaagtttcaa ggactgaata cacaattaaa
    10201 agagcaaaag agttatatga taatggagag gatatattta ttgctataga taaggctaga
    10261 gaagaatatg aggagatggt taaaagtgaa tatcttagct agtgtgatat tagtaatagg
    10321 aagttttata gctggtagag tttatgagta tagattgaat ttaaatgaaa atgatgaagc
    10381 tgattcaaaa gtacttttag atgtttttaa tgaaattagt gtgttaagag aagaaaataa
    10441 aagccttaaa gaaaagttac aagagaaaga gttactattc atcaatagat taatagattt
    10501 tttacatgat aaaaagatat gcgaatgttg tatttatgac tgtaagattg atgatattga
    10561 atatgattgt gaagatggta ttaaaaagtg gcttgatagc gaagaactta tatttgaata
    10621 gaagaaatat ctaattaaaa cagtttagag agttgcaaaa tgttttttaa taaaattatc
    10681 attgagatgt tttgtaactc tcaaaaatga aaataaggag gcgttgtatt gcttacattt
    10741 ttagatttat tcgcagggat aggtggcttt aggctaggga tggaaaaagc aggacataaa
    10801 tgtttgggac attgcgaata tgataaattc gcaaatttaa gttataatgc catgcacaaa
    10861 ccgaaggagg atgaatggtt tgaaagagat attagagaaa ttagaacaga aaatatccca
    10921 agagcagatg tctggtgttt tggattccca tgtcaagaca tttctgttgc agggaaacaa
    10981 tttggattca gaggagaacg ttcaagttta ttttttacag ttacaaaact tattagagaa
    11041 ctcaaagaag aagatagacc caagtattta cttattgaaa acgttaaaaa tctacttagt
    11101 gttaatggag gatttgattt cctcaaagtt ctcgttgaac tggatgaaat cggctatgat
    11161 gcagagtggc aagttcttaa ttctaaaaac ttcggagtac cccaaaatag agaacgaata
    11221 ttcattgttg gacattttag aggacgaagt acacgaaaag tatttcctat cgaaagaaaa
    11281 agtagaaaaa atcttgagca actaaataat ccaactcata gtacaaatag aatttatgat
    11341 gcagttggaa ttgctagatg tattagaagt caggcaggag gtggaggtgc taaaacaggt
    11401 ctatacttta tagacttaaa taaaaactct aaagtaacaa taaatgctag atgccttaaa
    11461 gcaaaatata atgcaggtgt gacaaataga aattgtgata atagtggagt tttagttaat
    11521 gcagttttaa cgcccgatag ggtaaataaa agacaaaatg gtcgtagaat taaagaaagc
    11581 ggagaaacaa tgttcacatt gacagctcaa gataaacatg gaattttgaa aaatggagat
    11641 ataagaaggt taacaccaaa ggaatgcttt aggttgcaag gatttccgga taaatattac
    11701 gaaagagcag caagtgtatg ctcagatagt caactgtaca agcaagcagg aaatgctgtt
    11761 actgcaaatg ttgtatatga aatagcaaaa agaatgggct aaaagttgca aaatgtcttt
    11821 tagtatgaat atttttgaag tgttttgtaa ctctcaaaaa tgaaaataag gggtgggata
    11881 aatgtatgaa tatatattaa gatggcaaat aggattatcg ttagaaaata gaaaaataca
    11941 ttatacatat ggaagtaaag aagctttaag aaagaaagca aaggcattgg ctaaagatga
    12001 aaatatagta ctaataacta tagataaggt agatgaagtt ataaaaaata ctataagcga
    12061 gaagattata gaacgttttg aaaatttata aggggtggaa ttatgataat acacaaattt
    12121 ataatacatg ttttagataa gaatagtgat acaccaatat tgaatgattt tgaaggtagg
    12181 gttaatcaag atatggtcct attttttcaa aagaaaataa gcaaagtatc aagagataat
    12241 gacatcagaa cagcagtatt taataactat agtaacaatc taattaagaa gtgttgtgaa
    12301 caaattattt atgatgaaag ttcattttta aataactcta aagagattgc agcttattta
    12361 tttgatgtta tgaaattgaa tgctacatta gaatcttgcg acttagcaat ttgtttatac
    12421 tctcaaaaag atgaaaagaa agttgctata ttaaagcttg attacaataa ttcgtatact
    12481 cattcaattg agtttaaaga tgataaattt aatatacaga tgtctaaaaa tgaaattaat
    12541 atacaagaga ctaagacggt taaaattgct gctttggttg gattgagtgg aatgaatgac
    12601 aaatatcatc ttagggtttt agacaaggat gcagagaagg aagaagctaa ttctaagttt
    12661 gttacagagt tcttaaatgc cactaagata aaagatgata agtataagac taagaagttc
    12721 aaaaatacag ctgagaattg gataactaat gctcttagta atgatataaa acaagcagag
    12781 gatgtaagaa gtatattaaa ttatactttg agagaaaagc atgaaattga tataaatgat
    12841 tttgttgata aaacaattaa agatgataag ttaaaagata gttttaaaga acatatggaa
    12901 gaaaaaggtc ttgttgaagg atttagtata gataaaaaat gggttgataa aaagcttaaa
    12961 aagagaaata taaaaactga caatggcttt gaaataaaag gtaacttaac tgattttgag
    13021 gacccaatga aatatacagt aagacaaaat caaaatgggt ctatagatat agttattaag
    13081 aatgtaacat tttatgagga aaagtaggta ctcatgtgac tattggctag agaaggagaa
    13141 gtaaataata agaggatgta aatttaaact agttaggagg aataacttat gaagattttt
    13201 ttattgacta tactgctaat aattatttgt atattagcaa attatgtgaa aaatcgcata
    13261 tataaaaaat ctataaataa tctaaaatat aaatattctg taggggaaaa gattatatat
    13321 catcaaataa actgttacta taacagaatg gttggttgtg aaattttaga aaaatgttat
    13381 agtacgaaat ttagaaaaag aaataccccg ctttataaag taaaagcata tgtaggtgat
    13441 aacgatacaa catgggttat accagagtgg agaattgaat gtcttgctac gacttatgga
    13501 gaatttccta aatattaaat aataaaaatt ggctggagaa ggagattgta aattatgttt
    13561 aacatctata aagtgaaaat aaagactaaa agaacattgg agcaggtaag aaatcaaagc
    13621 gtagactttg agtattcaga aaaaggatta aaaaatactc tgaaatacta taacttgatt
    13681 gatgatttaa aagtaatagt agttaaattt ggagatgaat attgtctagc taattacaat
    13741 gaagaagata gaaaaataat aatggaagca cattatcttt tagagcagga tgaatatact
    13801 ggatgttata taaatgaata tgaacgattt aaaaaagatt gggaaaatgg taattgtgat
    13861 ggggaagcct gtatggtatt ttcagatgat gaaattgaga taattgagaa gctaagggag
    13921 ggttaaatat gaataaaaga attaaaatga aaaaaagatt aattcataaa aagtgtgatg
    13981 aaagatgtgt caactatgac tttgtaatta gcaataacct tataacttgt aatgtgtgta
    14041 taggatgcaa atacaaagaa aatatggata aagtatgtga agagaactat aagaaattaa
    14101 gaagtaaata gaataaaata gtcaaggtaa gtttgtgaat gaaactagaa tgttatagac
    14161 ttactttgac ttataaaagg agtgtgttaa atggctaata tatattgtga aaattataat
    14221 tgtaaaaact actttgaaga tatgtgtatg cttgaaagaa ttgaaattaa taacttcaaa
    14281 gaatgcgaaa gctatcttga aggtaaaaat gagctatatg aattagaaaa tggatatact
    14341 atacatccta aagatttgaa aatggtgaaa agtaaagatt attctgttga agttactcat
    14401 attccaactg gtattacagt aaaatgccgt tctacaaata gtattttaaa aaataaaaat
    14461 aagtgtttgg aagttctaga agaagaacta acaaaaataa actctcactt agagctagaa
    14521 gatttacgct aaataggaag tgagcttatg aaacgaagaa gatgcagttg gtgtggtaag
    14581 ttattttatc ttgaagaaaa atctaaggat gtttattgtt gtaaagaatg taggaagaag
    14641 gctaagaagg tgaaaaaatg aaagtttttc ttgtaataga tggagagcca gttggcaagg
    14701 aaagaccaag aatgaatact tacgctaaaa ggacctatac acctaataag actaagaatt
    14761 atgaggacct aataaaatgg ctatatcaat ctaaagttaa atattacttt gaaggttata
    14821 taaaaatgac tttaagatgt tattattcta tagctaaaag taacagtaaa aaggttaagg
    14881 agcagaaaag aaataatgtg ttaagaccta gtaaaaagcc tgacattgat aatgtcatta
    14941 aagtagtagc tgattcactc aatgagatag cttataagga tgatacacag attgttgagg
    15001 ttgtagctag taaatattat agcgataatc ccagggttga ggttatatta gaagatgtta
    15061 tctaaccaac ggaaaaatcc gttcgttaaa ttatgccctt agtttttcat aaaaatgtga
    15121 aaaagctaaa taaagaatat atcaaacgac aaaggagaga taaattatga atgaaaatat
    15181 aaataaagaa ataacagtac ttggaacttt agaaatcgag ggaatgaaat ttcataacat
    15241 tgagggtgga tttggagaac ataagaaagc aatgctagta aaagatatag ccgagataca
    15301 taatagagaa tctagacaga ttaatgagct tataaataag aatagaaaaa gatttaaaga
    15361 tggaaaagat atattagatt tgttaggtgt cggtttggac gataccaaaa taaaagaatt
    15421 aggatttact caacaatcaa ttaattctta tagagggtta aaaaacaaag ggttattatc
    15481 tgggatttat atattatctg aaagaggtta tgcaaaatta ttaaaaatat tagaagatga
    15541 tatagcttgg gaattatatg agaagttagt tgatggatat ttctctatga gaaaagaact
    15601 aaataatcct cttttaagtg catcaaagga gttacaggct atatttatgc tagataagaa
    15661 acaagaagtc ttagaaacta aaatagagaa tgttaatgag aaattagaga actttatgga
    15721 tgatgcacca ctattcaata ttgaatgtga aagtattgta aaagaagtta agaaggtagc
    15781 aacaaaatca ctaggaggtc atggaagtaa ggcttataaa aataaatctt taagaggtaa
    15841 agtatacaat gatatatacc atcagattaa acgagagttt ggagtagata gttataaggc
    15901 tataaagcgt tgtcaattaa ataaagtatt agagattgta aacaattata agttacctat
    15961 agtgtttgaa gaagaaataa gacttttaaa tagtcaatta tcaatagtaa gttaaattta
    16021 ttcaaaaaaa aggaaaagga gtgctttcac actccacttg tcaaaaatat aaaactttta
    16081 tccaagatta ttataacata aacaggagtg tggaagtatg gataataata tcaataaaaa
    16141 agaactattt aaaaaagtag aaggtagatt acatcattat aaatttttaa gtgcagaaat
    16201 taagaatctt gaattagata tagaaagtag agaaaatgag atatttgggt gtaaggctgt
    16261 tggatatgat gaaaaagtaa gtccaacata tgcttttaat tcaactgttg agaatgagat
    16321 tataaaaaaa gaaagagata ttactagatt gaaaaaactg aaaaaagata aagaaataga
    16381 aaagaagaaa atagaaaatg cacttacatg cttagatata agagaagaac atttttttaa
    16441 actgttttat aatagtagaa tgaaaaatag tatggtttat atatccttag agatgaactc
    16501 agataggaaa acatgtagat gtgtaaggga aagattagtg tataaagtta tggatatgct
    16561 ttatccaaga attaaggaaa atgaactccc attatttaaa aattagaaaa ttccccagtt
    16621 tttccccaga aattcccact ttattcccta ctttctcccc tttttgatta aaaaagcatg
    16681 agataatagt attgtggaaa taaagatttc cctctcaaaa cttaatattt gactagggta
    16741 taagggattg ccctagtcac tacgaacaga ctaggcaggg cgtgaggacg ctgttagttc
    16801 aattctaact atgttcaaat attaatcaac gtatacacta aaagtagaga aattgagggc
    16861 aaaattttat attttgtatc ttaattcaga agtctaaaaa tcgggtgggg cttggtaacc
    16921 tcactcacca tgcaggtact ggtgtctagt ctaagttcga ttcttagaac ctgcgacata
    16981 atatatgtat ctccctacta aaaatgctaa gtttactcca aacttagcat tttaattttt
    17041 aaaaagaaaa aagaaatttt tattgtcata atactatttg tttaggtata ttataatgtg
    17101 catacttaaa attaaatact tagcaagcat ttgaattaat atacataaga tatatgacat
    17161 aattttttat agtgtaagtt atttaaatta attataaata acagtaattt tattatataa
    17221 aatgtacata ttgtgaataa taataataaa atcatgtaca aaatgccaac tgataattcc
    17281 tcgaaatata ttgcatattt aacgtaacgt cagtataatt aaattataat agtgaagtgg
    17341 aaggtggtac ttatggctac aaaaagtatt ttaaaaaatg tagatgtaag aaaaaaggca
    17401 tttggaagaa atctagtatc agctctagaa aatgctaaaa ataaacaaga aaaagaagtt
    17461 gtattaagta aaaaatgttc agaagtacca aaagataaaa taaaggatat attcgggaga
    17521 ttttaatgag tggctattta attgtaaact taagtaatat gctaggagag ctggaggaag
    17581 aagaagttaa aaaaattctc tccagttttt cttgtcccct taataaagat gtagaagaat
    17641 ttttaaaaaa caaagctatt gaattttcta aacagggttt ggctagtaca catttagtgc
    17701 taacttctta taaaggcaag cctgttatag ttggatattt cactctagct aataagtatt
    17761 ttacaataaa aagaaaaaca ttatcaaact ctttagctag gaaaatagtg aagtttggac
    17821 aatacaatga agaactaaga agatatatta ttggagcacc tttgataggg caaataggaa
    17881 agaattattc aaataattat aataaattaa tcaagggtga tgaacttcta aaaattgcat
    17941 gtgacaagat aaaagcagta cagttagata tgggtgggaa aatagtgtac cttgaatgtg
    18001 aagataaacc taaattaatt gaattttata aggataatgg atttgtagac tttggaaaaa
    18061 gaagccttga taaagacgaa acagattcgt tagatgggga ctatttagtt caaatgttga
    18121 aatatctaaa aaaataaaag tacataaaat ctaaaatgac tatcttgata gatggtcttt
    18181 ttttatacaa taaattaaaa ggagaatgaa attatggaga ttaagaaaaa cacacaagat
    18241 gtagtatcag aaagaaaaaa ttccctagat tctgaattca agatacctgc aagtggtgtg
    18301 tgttatatgg ctgagtttat aaaggaatct agggaaatca taaaagaatt agataaacat
    18361 tttgaaagtt gtctagatgt tttatctaag gcaagactct aaatattttg aatatgctga
    18421 atcaagcatg gtttgccaat ctgggaaatc agtattttta actataaata aatcaaattc
    18481 attatcagga atagctaaaa agtcttcttc tgaattgact atgtaattac caaatgcaag
    18541 tagttcatca aaagaatcaa aattagtgtg ttggttcata aatttcttgc taagaattat
    18601 tgtgcgaatc ttatcaaagt caggttttaa attttgttcc attctttcaa ttttcttttg
    18661 aaattgcttt aaatttctaa tgtcaatatt tttactcata agaacacctc ctttcaatag
    18721 aatattagca taaaattgtg gtgaattctg ctattgtcga acgattgttg aaggatattg
    18781 tataataaca tagaatttac tatactataa ggaggtgatt atgtgggatt tgagataagt
    18841 ggtaatttga attttgacag tgttattgat gatttaaaaa aagaagttga aaataaccct
    18901 actatattta catcacaaaa tgttggaaat aagttcaaag aaaaatgtaa aatatgcgaa
    18961 aaaatatctg aatttgaaat actagaagat ggtaaagtta aatgtttaga atgtgggact
    19021 gaatttgaat tgaatcttaa agtagagtaa acaaaaaaag aatctcaatt atgaggttct
    19081 ttttttattc ccaaaacaaa caaataaaga ggtggtgatg tgcaagatgt caaagaaaag
    19141 gtaaaacaag attacttaaa aggaatgaaa caaaaggaaa tatcatcaaa gtatgacatt
    19201 agcttaaaca ctttaaagtc atggataaaa agatacaact gggctagtga aaaaaagaag
    19261 ggtgcaccta taaataaaag aggtgcaccc ttttctaata aaaattcagt tggtcatggt
    19321 gctccaaaag agaataagaa cgctgaaaag tttggtttct tctcaaaata tctacccgaa
    19381 gaaactaggg aattgataca agaaatatcc ataaaagata aatttgatat tctttgggag
    19441 cagataacaa tccaatacgc agcaataata agagcacaaa agataatgta tgttaaagac
    19501 aaggaagaaa tgattaaaga attaaagaaa catgaaagta cagaaaatgg agagaagata
    19561 gagtatgaat ttcaatttgc atgggatagg caagcatctt ttcttaatgc acagagtaga
    19621 gctatgagtg aacttagaag tttaattaaa cagtatgatg aaatgattca taaggattgg
    19681 aatttggcta cagaggagca gaaaacaaga gttgagaagt tgaaatgtga agttgataac
    19741 ctaagtaaag atgatattgg agatgatgag ttgaaaataa gtgtagatta tggtgataga
    19801 aatgatagtt agagtaaatt ttaatccaga tttcaaggaa gctaatttta ctaaaaaaag
    19861 atacagagca atgaaaggtt cagcagggag tggaaaatct gttaatgtag cacaagacta
    19921 tatactaaag ttaggagata agaagtatca aggagctaat ctattagtag ttagaaagtc
    19981 agaagctaca cataagtatt caacgtatgc agagcttaca ggagctataa atcgtattta
    20041 tggtaaacaa gctgataagt attggaaaac tactttaaat cctttagaaa ttaagagtaa
    20101 agttactggt aactctataa ttttcagagg agttaatgat gcaaaacaaa gagaaaaatt
    20161 aaaatcaatt aacttctcga aaggaaaatt aacatgggtt tggtgtgaag aagctacaga
    20221 acttatggaa agtgacatag acatactaga tgaccgttta agaggtattt taactaatcc
    20281 taacctatac tatcaaatga catttacatt taatccagtc tcagctactc attggataaa
    20341 aagaaagtat tttgactata aaaatgatga tatatttact catcatagta cttatctaca
    20401 aaatagattc atagatgaag cttactacag aagaatgcaa atgagaaaag agcaagaccc
    20461 agaagggtac aaagtctatg gtcttggaga atggggagaa actggtggag caatacttaa
    20521 aaattatgtt atacatgaat ttactacaga atttgagtat tttgacaata tgaggttatc
    20581 acaagacttt ggatttaacc atgcaaatgt agtacttaga attggcttta aggatggaga
    20641 gttatatata tgtaacgaaa tatatgtaca tgaaatggat acctcagaaa tcataaagat
    20701 tgcaaatagt ataggtttag aaaagactct atttatgtac tgtgatagtg ctgaaccaga
    20761 tagaattaag atgtggaaga atgcaggata taaagctaaa ggagttaaaa aagggccagg
    20821 aagtgttaaa gctcaaatag attatttgaa acaattaaga atacatgtac atcctagttg
    20881 cactaatacc ataaaagaaa tacaacaatg gaaatggaaa caagacgaaa gaactggatt
    20941 atatcttgat gaaccagttg agtttatgga tgatgcaatg gctgctctta gatattctat
    21001 agataataag cttaaaaata atggaataag cttcttaaag taaaggaggt gttaaatatt
    21061 tatataagtg aaacagattt aataaaagtt cagttaaaaa aagagagcac ctttaaccta
    21121 gtaaaagtca tagaacacta catcttaaaa cataggccag aaaaatataa acaaggagaa
    21181 gaatactatt atggtaatac tgatgtaaac aataagagaa gatattatct cttagatgga
    21241 gctaaggttg atgattttac taaagttaat aataaagcaa ttaacaacta ccataagctt
    21301 ttagttgacc aaaaggtagg ctatagtgtc ggaaatccca tagtatttaa tgcagatgat
    21361 gataatctca ctaagctttt aaatgactta ctaggagaag agtttgacga tacaataaca
    21421 gaactatatc tcaatgctag taataaaggg gttgaatggt tacatccata tattaataga
    21481 aaaggtgagt ttaaatatgt aataattcca gctgaagaag caattcctat ttgggatagt
    21541 aaaagacaga gggaattagt tgcatttatt aggttttatt atattgaaga tatagatgga
    21601 aataaaataa aaagagttga gtactacaca gaaaatgatg taacttactt tgttgaaaga
    21661 ggtaatagtt ttgttcaaga atttttatat gatgaatatg gaaaaatgac tgatatacaa
    21721 gaaggtcatt ttagaataaa taacaaagaa cagggatggg gtaaagttcc atttatatct
    21781 tttaaaaata atgaaaagtg tgtctcagat ttaactttct ataaatcatt aatagatata
    21841 tatgacaata atatttctac actagcagat aacttagatg aaatacaaga ggttatttat
    21901 gtattaaaag aatatccagg aacaagtcta caagagttta tagataatat aagatactat
    21961 aaatcaatta aagtagatgg tggaggtgga gttgataaac tagagataaa tataccagtt
    22021 gaagctaaaa aggagcttct tgatagatta gaaaagaata taattatctt tggtcaagga
    22081 gttaatccag aatctcaaaa cacaggtgac aaatcgggtg tagcacttaa atttttatat
    22141 tcattactgg accttaaatg ttctaagact gaaaagaagt ttaaaaaagc aattagagag
    22201 cttttatggt ttgtgtgtga gtatttaaag ataagtggta gtaagagcta tgattataaa
    22261 acagttcaaa ttacttttaa tcactctatg ataataaatg aagctgaaaa gatagatatg
    22321 gcagctaaat caactggaat tgtatcagat gaaactattg tttctaacca tccttgggtc
    22381 gaggatgtaa atgacgaact tgagagactt aaaaaacagg aagatactca aaaagagtat
    22441 gatgatttaa ttcctaataa tcaagatggt gttatagatg aaacataaag attattggag
    22501 gaagagattt gaacaattag aagaagctca aaataacaaa agtgtaaaat attatcttga
    22561 attagaaaag caatataaac tagctatgaa tagtatagaa aaagatatat tagcatggta
    22621 caacagattt gccaaaaatg aaggaatatc tttattagaa gctaagaaac tactaaatac
    22681 aagagaacta gaagagttta aatggagtgt cgaagaatat attagacatg gtaaagaaaa
    22741 tgctataaat caaaagtgga tgaaagagtt agaaaatgct agtgcaagag ttcatataac
    22801 aagacttgaa gctttaaagt tacaaataca gcaacaagtg gaagtgcttt atggaaatga
    22861 acttgatggt attgataaat taatgagaca tatttataca agtggatatt atcatgcagc
    22921 ttttaatgtt caacaaggag taaacgttgg ttggagttta atgaatcttg atactaatag
    22981 aataaataaa gttatctcta aaccatggac tagtgatgga ttaaatttta gtgaaaggat
    23041 ttggggcaaa catagacctg ctttaattaa tgagttacat actaagctaa ctcaatcaat
    23101 tattagaggt gaaaatccaa agaacctagt aaatgacttt tctaagagat ttaatgtatc
    23161 taaatcacaa gctaagaatt tgataatgac tgaatcagct ttctttgcat cagcttcaag
    23221 aaaagattgt ttcaatgatt tagatgtaga gaagtatgag attattgcca cactagactt
    23281 aaaaacatca aatatatgta gagagttaga tggaaaagta tttgatatga aggattatca
    23341 agttggagtt acagctccac catttcattg tcgttgtagg acaacaacag ctccttggtt
    23401 tgaggatgaa gaaggttaca gagcagcaaa aggagaagat ggaaaaacat attatgtacc
    23461 atctagtatg aagtataatg agtggtatga gaagtatgtt aaacataata gtatcttaga
    23521 aataaaaaat agtgctataa tagatagcat aaaagaagat attaaaaatg gtaaatataa
    23581 tttaaatatt catgatggga aacaaggaaa acatttaaaa gagcataata attatataga
    23641 aggaagaagc tatttaacta taacaaaaga agaagctcaa gaacttgtga ataagcatgc
    23701 tggcaatgga atcataaaat ttaatcgaag tggagaatgg gataaaaaag aacttataga
    23761 agttgataag aatatagggg tcaatgttaa taatattacg ggtgaaaaaa ctcttacaaa
    23821 taagtttaag atacattatt ccaaaactgg aacacatata gtaccagctt tataaggagg
    23881 aaaaataaaa tgaaattatg ggaatatgta gggaaaaatg ttcaaataac ttgtgtagat
    23941 aagcaaataa taagaggaaa gtgtgatgga tatacacaag ctttagataa tgaaccagaa
    24001 atagcaagta tatcaatagc tagggatggt tatggaattg aagtttatga aaatgaaata
    24061 gaatctatcg aaaatataaa taaggaatga ctaagcatgt acttaaaaat aagtagatgc
    24121 ttttattttg taaaaaatga aaggagaaat ttaaaatgga ttggttaaaa gaattgctag
    24181 aaggaataaa aatagaggat aacaagattg atgtagcttc tttacaaaag tctatagaaa
    24241 agaaaataaa agagactaca attactcaag aagattatac aaatcttgaa acacagctta
    24301 atacagctaa tgaaactatt aaaaagtttg aaggaggtat gacaaaagaa gatgtagaga
    24361 atctaaaaac aacttatgaa actgataaga aaactttgga agaaacctac aaaaaagaaa
    24421 ttgaagaaaa ggactttaat tactggttaa atgatgcttt taagtctatt aaatgtaggg
    24481 atgaaatagc gttaaaagct catttagata tagaagcact aagaaatagt aaagatagac
    24541 aaaaagcttt tgaagagcaa ataaaccctt tgaaacagga taaagattat ttgtttaatg
    24601 caacactaga aggtgaagag cctaaaatag atactataac accagggcaa gagcctaaga
    24661 taaatgattt tggttttaat tttactgggg taagacctca tgaaaataat aataaatagg
    24721 aggaaataaa atggcagcac taaattatgc aaaagaatat tcaaatgttt tagcacaagc
    24781 atatccttat actttaaact tcggggattt gtatgcaaca ccaaataatg gaagatatag
    24841 atggactggt tctaaaacaa tagaaatacc aactatatct acaactggaa gagtagattc
    24901 aaacagagat acaatagcag tagctcaaag aaactatgat aatgcttggg aacctaaggt
    24961 attaactaat caaaggaaat ggtcaacatt ggttcatcca gcagatataa accaaactaa
    25021 ttatgtggct tcaataggca atataacaaa agtatataat gaggaacaaa agtttccaga
    25081 gatggatgct tactgtatat ctaaaatata tgctgattgg accgcattag gtaatacagc
    25141 agatacaact gttcttacaa caacaaacgt attagaagta tttgataagt taatggaaaa
    25201 aatgacagaa gctagagtac ctgaaaatgg aagaatattg tatgttactc cagtagtaaa
    25261 tacacttatc aaaaatgcaa aagagataca aagaacagta aatataaagg atgcaggaac
    25321 ttctcttaat cgtcaaacaa ctgatattga cacagttaaa ataattaaag taccatctaa
    25381 tctaatgaaa actgcatatg attttacaac tggatggaaa gtaggagcag gagctaaaca
    25441 aatctttatg tccttagttc acccaagtgc aataattaca cctgtttctt atcagttctc
    25501 taagttagac gaaccaacag cagttacaga gggaaaatac ttctactttg aagaaagttt
    25561 tgaggatgta tttatattaa ataaaaaagc tgatgcaata caatttgttg ttgaaggagc
    25621 tggagcataa tggcacaagt aaggaaatta aatagaatat taaccataga agagtgtaaa
    25681 atagatgatt tcttagagat gggatatgat ttgatagatg aaactggtaa ggtagtaagg
    25741 tatggcaagt cattaaatgt aaaagattta atagctgaaa ataatatttt aaggtcaaaa
    25801 gttgagtctt tagaagaaga aaataagcag cttaaagaga aaaataaact tactaaaaag
    25861 taggtgaaaa ttatgggaaa taatataatt gatgatatag aaaaaagact tgaaagtttt
    25921 ggatatatat taaaagatgg ggataagtgg ttaatagatt ttgtaagaga aaaaatagaa
    25981 aatattatta aactagattg taatataaaa actatgccaa ttgaattgaa agaaattgaa
    26041 gctgatatga tagttggaga gttcttattt accaagaaaa atatggggca attagatata
    26101 gaaagcatta actttgaagc tgtagaaaag tctatatcag aaggtgatac aaaggtagat
    26161 ttcgctatag gaagtggctc tcaaacacca gaacaacgct ttgatagctt aatagcttat
    26221 cttactgctt atggtaagaa taagatatta acctttaggt gcttaagatg gtaagtaaaa
    26281 ctagaaaagc aatagaaatg ttatatagat ataaatgtac tatagttgag tatcagccaa
    26341 tcaaagaccc tgtaacaaaa cgaactaaca ataaagaagt gattgtatta gaaaatcaac
    26401 catgcaagct ttcatataaa aatatagttt ctgctacaga aggaaaatta gctaagctag
    26461 agcaaactat taaactcttt atatctccag atatagaaat taaagcaggt tcaaaactta
    26521 ttataaatga taaagagtat gtaagaagtg gagaatcagc tatatatcca aatcatcaag
    26581 aaataatact tgagttattt aaggataaag cataatggct agatggggca gtgttgattt
    26641 tagagagttt aaaagagttt gtaaaaagat ggagaagctt acaaagattg atttagataa
    26701 gttttgcaaa gatgcagcaa gagaattagc agcaagactc ttaggaaaag taattagaag
    26761 gacaccagtt gatacaggat tcttaagaca aggatggaat ggagtggctt atgctaggtc
    26821 gcttcctgtg tataaacaag gaaataatta tattatagag gttgttaatc cgactgaata
    26881 tgcaagttat gtaaatttcg ggcatagaac taaagacgga aaaggttggg ttaaaggaca
    26941 acatttctta acaatttcag agatggaact acaaagccaa gttgataaga ttatagagaa
    27001 aaagttatta atattactta aaggagtatt tgatgcttaa taatattata gatggaatat
    27061 cagtaaagtt agataaatca tttggagaaa aatatacaat ttatagtgag gatgtagagc
    27121 aaggtattaa tgaaccttgt ttttttattg ttcctttaaa tccaagcaag acaccatatc
    27181 caagcgggag agaattaaag aaaaattctt ttgatgtaca ttatttccct cgttcagaag
    27241 ctaagaattt tgaaataaat gagatagctg agatgttact ggaagaatta gagtatatag
    27301 aaatcaatgg agatttagtt agaggcacaa atatgaattt tgaaattata gacaatgttc
    27361 ttcacttctt tgttgattat aactacttca ctataaagag taataatgca gataaaatga
    27421 atacagtaga gttattcggt ggtttgaaga gaggtgataa ttttgagtaa gacattaagc
    27481 aaaggaaccg attacaagtt tactaaggag cagatagtta attctaagaa gtatgtaaat
    27541 agaaaagact tattaaatgc aattttaaaa gaaaatgagt tatattcctt ctcagaagta
    27601 gaggatagaa taaataaatt catgaaagga gtgagttaga tggctttagg tggaggaaca
    27661 tttgtaacac agaataaagt attaccaggt agctatataa actttgtaag tgccacaagg
    27721 gcaaccagtt cacttagcga tagaggtatt gttgcaatgc ctttagaact tgattgggga
    27781 attgatgaag aagtatttca agtgactagt gatgattttg agaagtattc aactaagtat
    27841 tttggatatg attatacaca tgagaagttg aaaggtttga gagatttatt taaaaatata
    27901 aggctaggat atttctataa attaaataaa ggtgttaaag ctagttgtag tattgctaca
    27961 gctagatgca gtggtataag aggtaatgac ttaaaagtta tagtaacaac aaatatagat
    28021 gataatgcta aatttgatgt tgtaacactt ttagataata agaaagttga tactcaaata
    28081 gctaaagtta ttacagaact gcaagataat gattatgtca cttggaagaa ggaagcaaca
    28141 ttagaggcta cagcaggatt aacttttact aatggaacta atggtgaagc tgtgacagga
    28201 acagagtatc aagcttttct tgataagata gaaagttact catttaatgc actaggatgt
    28261 ttggctacaa cagcagagat taaaagtttg tttgtagagt ttactaagag aatgagagac
    28321 aaagttgggg ctaagtttca aactgtatta tataaaaaga atgatgcaga ttatgaaggt
    28381 gtagtatctg ttgaaaataa gattaaagat actggattat tagaatctag cttaatttac
    28441 tggactactg gagctatagc aggatgcgat ataaataaat ctaatactaa caagcgatat
    28501 gatggtgaat ttgatgtaga tgttaattac actcaaatac atttagaaga agctttaaaa
    28561 actggtaagt ttatatttca taaggttgga gatgaagttc atgtattaga ggatataaat
    28621 acttttgtta gttttacaga tgaaaagaat gacgactttt caagtaatca aagtgttaga
    28681 gtacttgacc agattgctaa tgatatagcg actttattta atacaaagta cttgggtgaa
    28741 gtaccaaatg ataaatctgg tcgtatctcg ttttggaatg atgtagttaa gcatcatgaa
    28801 caactgcaaa atatgagagc aatagaagat ttcaaagctg atgatgtttc tgtagaacct
    28861 ggaagcgaca agaagactgt tgtagtaagt gatgctgtaa aagttattag tgctatgagt
    28921 aagctttata tgactgtttc agttagttaa caataagaaa ggagaataat aatggcacaa
    28981 caaataaaag caagagatac aataagtgca tctaaggcag agtgttttgt aactataaaa
    29041 ggtaaaagat ataattttat gcaagctatt aacttagaag ctaaaatgga aaagaataag
    29101 agtgagatac ctatattagg tagtactaca aaaggaaata aatcaacagg aagtaaatat
    29161 tcaggaaatg caacatttta ttataatacc tctatattta gagaattgtt gtatgagtat
    29221 aaagaaactg gtgaggatat ttacttcgat atacaaatta ccaatgaaga cccaacaagt
    29281 tcagtgggtc gtcaaactat aatactggaa gattgcaata tggactcagg cataattgct
    29341 aaatttgatg ctgatgggga gtatttagat gaagatatgg attttacttt tgagaattgg
    29401 aaattagttg agaaatttaa tatagcaaat ggtatggagt aaaatacaca tttatgattt
    29461 atgtatgtgt attttttatt tataagaata ggagatgatt aaaattaagg ataaatatga
    29521 gataaaagat tcaatttctt ttgattatag caataaaaga cctttggaag aacgtgtcag
    29581 cgagatgtat aaaaaggcag gaaaatatct tatagatatt tcagataagt tagcaacaga
    29641 tacaattgat ggttcgtcat taaagccaat aatcataaaa tttgaaataa atgaagctgg
    29701 tgttgcaaca atagaaaaac aaacaaaata tttggtgatg gaggtagaat aagaatatgg
    29761 gagatttaaa cgctttttta agtcaaaatg caataaaagt agagaataga aagtatgtgg
    29821 caagtgaaag gtttatagga gaagatggaa aagcaatcga atgggaactt aaagcaatag
    29881 attcagatag agatagacaa ttaagaaaag attcaactat aagagtacct gtactaaata
    29941 aaaaagggaa agcaacaggg caatacacta gtgaaacaga ttttaatact tatactttga
    30001 aactgtgtgt agaaactgta gtatttccag atttacatga tgcagaactt caaaatagct
    30061 atggtgtaat gggagcagag gaactattaa caacaatgtt aactcctggt gaatacacag
    30121 acctttcaag tgaggtagga gaagtgaatg gttttgatag gacttttgaa gataaagtag
    30181 aagaagcaaa aaactaattg aaggaggcga ttatgatgct agtgtagctc attattgcct
    30241 tcataaattc aaatggaaac cacatgaata tacagattta ccagacttcg agagggcatt
    30301 tgttgctgct tctatagata ttaaagtaga agaagaaata aaagaagaaa aaaagattgc
    30361 taaagaagct agaagaagta gaagaagata aaatataggt aaaatatgta agaattatat
    30421 gttataataa ttgtagcaag aagatgtaat ctacaattta tagagtggag ttcatactgg
    30481 gataaaacct acttcctaat gaaaggaggt gggaagtatg gacaattttt tacttagtat
    30541 attagctagc ttgatagcta gtttaattgg atatatcgtt tgtagatgta tcaaaaacgt
    30601 aaaaagccac tctactcgtg gcaagagtaa aagtggctgg gaacttggtt ttaaaataaa
    30661 gttccgcaaa tttaaataat ttatattttt taaaattatg aacttcactc taccgctaaa
    30721 tagattgtag ttcttcatgc ctttattata ccacaaatta gaaaaaatat tgtttatata
    30781 aaataaaaaa taaaaatttt tattaaaaaa ttgaaaactt gattataaag caattaattt
    30841 ataaaatata tataaataag taggtattta tttacttgaa tttcattgtt tatataaaaa
    30901 aaatggaaaa atatgtaata attatatgtt ataataattg tagcaaggat aataatcgaa
    30961 agtgcgaagg gtgattattt tcatattaaa cgccaaattc caaataagga aggaggtgaa
    31021 attatatgat aggtttttta ttaagcatac tagctggtgt tatatcagct tatatttatg
    31081 acaaaataaa aaatcaccca gacgccaata agggtgattt aaaaaaataa tattttcact
    31141 taacaactga aaataatcac tctttgtagg agtaaattat ttccttgctt ttattatacc
    31201 acaaattggt acagatattc aaaaataata tttttatgat ataataaaaa tgtagagatt
    31261 ttgcagtgag cgatatttgt gataaattga agtttaacag ttgcaatata aggcgttgag
    31321 ggtgtgtgat aaatgttatc aattgtacta ctcatggttc actgcaaatt tgagagagat
    31381 gcgtatgtgt aggtattgga aatgccaagt ttattttggg gttttagatt aattatatgg
    31441 aatgtaaata ccgctttacc tgctgtagta tttaaagaac taataagttt tagattaact
    31501 atatggaatg taaatcctta tacacgacat tataatataa gtacgttttt agttttagat
    31561 taactatatg gaatgtaaat tgtttatctt ttcattgttc atgtacattt cattgaagtt
    31621 ttagattaac tatatggact taaaattaaa aatactgaaa aacacttact tttatggtag
    31681 gtgctttttt atattaaaat ctgtgtactt aattgaaata tttggtaaaa tatgtaagaa
    31741 ttgtatgata taataattgt agcaaggaaa ataataattg aaaagtgcta agagtggtta
    31801 tttccatatt tgaataccaa attccataac ggaaggaggt gtaacagtat ggtgataaat
    31861 tttttattga gtatactggc tggtgttata tcagccttca tgtatgagaa aataaaaaac
    31921 cactcaaagg ccaataagag tggtttaaaa aaataattct ttaaatcaat tttgatggaa
    31981 atagctactc ttgtataaag taaattattt ccttgctttt attataccac aaattggtac
    32041 agatattcaa aaataatata tttatgatat aataaaaatg tagagatttt gcagtgttcg
    32101 atttttgtaa taaaatatgg cttaacaatt ggaatacaag gcattgaggg tgtgtgataa
    32161 atgttatcaa ttgcactact catggttcac tgcaaattta agagagatgt gtatgtgtag
    32221 gtattggaaa tgctaagttt attttggggt tttagattaa ctatatggaa tgtaaatata
    32281 acatatgaag gtatggaaca gacaagtaaa caagttttag attaactata tggaatgtaa
    32341 atcgcatttg taagagttga ctttatattt tcccaagggt tttagattaa ctatatggaa
    32401 tgtaaattaa aaacgattaa accaaaaaac atcaatctga ttaaatgttt tagattaact
    32461 atatggaatg taaattttgt tgttgtacaa gggaatgtaa ctaaagatgt aagttttaga
    32521 ttaactatat ggaatgtaaa tgataattgc tattttacga aaggtacggt tgtaattgtt
    32581 ttagattaac tatatggaat gtaaattagg gaattaggaa atggctattc tccccctata
    32641 tccgttttag attaactata tggaatgtaa atatttgaac atttgttaca gcattagaga
    32701 tattaattgc gttttagatt aactatatgg aatgtaaatc atcatagtca cgtatatttt
    32761 ctttaaaagt caaagtgttt tagattaact atatggaatg taaatccagt catgaaacca
    32821 aaagaattta gaccagattc agttttagat taactatatg gaatgtaaat ttttcatcaa
    32881 gtatatttat tgttaattgg tctggaaagt tttagattaa ctatatggaa tgtaaatttc
    32941 gcaacttatg atggtgaaat gattacatta acaggtttta tattaactat gtggtatgta
    33001 aagattactc taaaagtctt tttatcattt tctacctcaa ttttatatta actatgtggt
    33061 atgtaaataa agcaaaagat aggaatgata attttaaaac tccagacttt tatattaaca
    33121 atgtggagaa aaactaaata gaagaaagaa gcacttactt aaatggtagg tgcttttgtt
    33181 ttgctcaaaa ttggtcggtt gagtaaaata attagaaaaa aagatatagc tgaggtagtg
    33241 ttttacgacg ctagcttcaa taaaatttta tttgaaaaat attccaaaat agcttgactg
    33301 taactcgtta caatgttatt attaatgtaa cgagttacag aaaagaggtg aataaaatag
    33361 caactaaaag tagagcagag tatatgaaaa atcgtcgaaa agataaaaga ggttttagtg
    33421 tacttttaga caaagaaaag ttagataaat ttgatgaagt gttagaagag aagaatctaa
    33481 ctaagaaaga atggctagaa gaaaaaatcg acgaggaact ggaacaaaag gaataaaaaa
    33541 taagggtcac tcccaccgac caaagtttga gcaaccctta ttgacgtata ctatacatca
    33601 actaactata gtatacgtca ttccttaaaa aatttcaatt aaggagtgta atattatgaa
    33661 aaatgaatta atgatgtttg aagaaaagaa agttgaagta cttgaatata atgggcaagt
    33721 tttatttaat ccatatgatt gtggaagatg tttagagtta agtgatagtg caataagaaa
    33781 tcatttatct aaaatgaatg atactcaagc tgtattatta aaaaattcta atgtcctaga
    33841 taaggacttt agaaaattgc ataacacagg tgaaaagttc ttaacagaga gtggagtata
    33901 taagttaata tttaaatcta aaaaagaaga agctgagaga tttcaagatt ggataagtga
    33961 tgaagtactt ccagccattc gacaaactgg tgcatacata acaaataatg ctgacccaga
    34021 taagttgaga gaaaaagcaa gcgagattga aaaattacaa ttagcttata acagtacatc
    34081 tatgttaaaa gaattgctag atgatgcagg ctttgacaac aaatctaaac tattaacagc
    34141 taagacatta tataaaaagg caggcattga tttaccaatt gagataaacg aagaagaaca
    34201 ttactttgac acaaaacaaa tagcatctaa actgaaaata tattctaaga gtaataaacc
    34261 agcacagttg gctgtttgtg agattattaa aaagataaaa ttagaagaaa atgaagtaaa
    34321 aggagtttgg gaaacgaatg gttcttggac tggtactgta aataaatata caaagagtgt
    34381 aatagataag gttagaactt ggatagagga gaataataga cctactaaga ttgcaggtga
    34441 gaagaagaat ttccatgttg tatataagat tgagtaaatt tgattgtatt aaataatata
    34501 ttttagttta ttttagtttt gagggggatt aatacaatgc gtgaaagttt acttaataaa
    34561 tataatttaa aaactgatga agatgtagaa tactttgtga agcttgctaa tgcgttatat
    34621 gaactaaaac tgaatagtga agaaaaattt caagaatatg cagagatatt aagaggtatt
    34681 cttagagaac aagaagagag aaaataagta aaataatata gataaagcac ttgaatatta
    34741 catagtttca agtgctttgt ttgttaaaaa atggtataat ataggtagga aattatatta
    34801 acaatgtggt atgtaaagaa gttagaaatt aaagtaacaa ataaaaataa aactatttta
    34861 tattaactat gtggtatgta aatagcgctc ccaagacata caacgaatca gttacattaa
    34921 attttatatt aactatgtgg gttcaaaact aaataaacaa agaagcactt acttttggta
    34981 ggtgcttttg ttttgcttat aacttttcat catcttcata ttccataata tcacctggtt
    35041 ggcagtttaa agctttacat attttatcaa ttacatcaag tgaaacattt ttatttgaag
    35101 atagtttggc tattgtagta gaagaagctc ctattttgag tcttagttct tctttagtta
    35161 tacctcttct gtttagtaag tcaattagtt taaaaaattt tatagacatg ttaatacctc
    35221 ctatatattt atataatact atatatcttt attaaagtaa agatatattt atcaaaataa
    35281 ataaaaagta ttgacattat ttactaaata atgtattatt agagtataaa gataaagaaa
    35341 tctttataaa ggtaaagtaa taagggataa aataaggaat attctctctc gtcaaagttt
    35401 aaatattcct tatgacatat aactaatatg taatataatt atatgtcatt ccttaaaaaa
    35461 aatcaattat taaggagtgt gtttttatga acaatttagt attaattaac aaccaagagt
    35521 tgcaggtcaa ggagtttaat aatcaaagag tagttacatt taaagaaatt gaccaagtac
    35581 atgaaagaac agaaggtaca gcaaagagaa atttctcaga gaatagaaaa cattttatag
    35641 agaacgaaga tttctttttt gtaaaagcaa gtgattttga aaagtacgga aatcgtactt
    35701 tagaaattcc taatcgtgga ttaactttaa taactgaaac aggctatttg atgttagtaa
    35761 aatcttttac agatgactta gcatggaaag tacaaagaca attagtaaat agttatttta
    35821 gagttaaaga agaaataaaa acattagaag cagtaaatga gtcaattaaa ttaataactc
    35881 caatttttga agatttaaaa attgataaaa gtatgcaatt tcttgttgct aaaacatttt
    35941 tcaaaaaagc aggagttgat attccacttg aaattgaaga aaaagagcat ttttacgata
    36001 caaaacagat tgcaagaaaa ttaggacttt acacaatgtc taataaacca gcatttcaag
    36061 cagttaaaca aattataaga aaacttgata ttaaagaaga tgaaacgaaa acagtactag
    36121 aaaccaatgg ctcttggact ggtactgtaa caaaatattc taataaggtt acagaaaaag
    36181 tcaaagtgtg gttgaaagaa aataataatc ctatctcaat caaaggagac aagaaaaact
    36241 actatatatt gtataaaaat aattagattt tagtttagtt ttgaggggga ttaatacaat
    36301 gtatgagaat ttacttgata tggatagaat agaacttatc aaagaacttg gaagtatctt
    36361 tgaaaaaatg aaaaatgaaa atccagataa attttataga tttgtaagtt tagtgaaaga
    36421 agaatgtagg aaaaaagaaa agaaagagaa taaataatat agataaagca cttggatatt
    36481 atgttgtttc aagtgctttg tctgttaaaa aatggtataa tggatataga gaattatatt
    36541 aacaatgtgg tatgtaaata ctaaattaga ggtcgagaag gctattgaat caaaaggttt
    36601 tatattaact aagtggtatg taaatcgatt ttattataga gtagaggaag ggcttgtaaa
    36661 tggttttata ttaactaagt ggtatgtaaa gtatatggac attaaaaacc catttgactc
    36721 ttataagttt tatattaaca atgtggtatg taaattgttg tatttgtgga agtgaaaagg
    36781 gacttatacc agttttatat taactatgtg gacttaaaat taaaaataat caaaaacact
    36841 tacttgaata gtaggtgttt ttttaatgaa aggaggtgat aataatgtaa aaattttact
    36901 tatatagtat aataatctta taaaattatg tagggggtaa tattatgggg ttatttggag
    36961 gtaaagaacc atgcagcata tgtggaggaa agggtaaaaa taaagtttta gaaaatgaat
    37021 atttatgtaa taattgtttt attaatttca caatattttc tagagaaaga ttaaaagcaa
    37081 ctagtgcaat gcaagtatta gctgaccatg aagggataag aaaatttata aatttttcta
    37141 aaacaaacag agaactgtta gcaaaatttg ttgagacaaa tagaattaat aaatttgtat
    37201 ccatcgacga agataataac tttattaaaa tatcagatat tcgcaaaggt ggagatgtaa
    37261 tagaaaatgt atatgcaact gatgaaatta tgcaatttga acttttggaa gatggagagt
    37321 ctatagctag tggaggattg ggaagagctg tagttggagg agctttgttt ggtgctactg
    37381 gagctatagt tggtggaata actggcaaaa aaacaacaag aaaagttgtt gatacattta
    37441 aaattaaaat aacctttaat aatatcaata atcctttgga atatgttaat ttgattaatg
    37501 caaaaacaaa aactaattca tctatatatc agaatgcttg taatgaagca caagaaattt
    37561 tatcagtact ttcaataata ataaaaaata atgataaagc tgataatgaa caaagtaaaa
    37621 ctagtgattc aatagaacag gtcaaaggtt tgaaagagtt gctagactta ggagcaataa
    37681 cagaagaaga atttaatact aagaaaaaag aattattgaa tttgtaatat tacaaagcac
    37741 ttacttaggt aggtgttttt ttatgtaaaa atttgagaaa ggagagtgaa aatatggcta
    37801 caatacaaac atccattaga atttttgatg gaatgactcc cgcatttcgt aatatgacta
    37861 atgctattaa cactacaatt aacagttttg ataggctgca acaaaggttg cataatccgc
    37921 ttaacgcagg tggaatacaa atatctcagc agagcttgaa taatattgaa aatatcttaa
    37981 ctagaataga acagaatata gaaaaagcag atgaacaaca gagaagattt aacgaagata
    38041 ttaacaaggg ggtaagcaat acagatagat tgcttggaag tgttaaaaaa attgctggag
    38101 cttatatggg cttaaagacg ataggaggat taggtagttt aagcgaccag atgaccagca
    38161 cgaatgcgag attagctatg acaaatgatg gtcaattatc agatggagga ttaaataaaa
    38221 tgatattcca atctgctgaa aggtctcgtg catcttactt agacacagca cagatagtct
    38281 caaggatagg tatgaatgca ggaagtgcat tttctagtac tagagaaatt gtaagttttg
    38341 ctgaacaact caataaaaag ttcataattg caggagctag tacccaagaa atgagttcgg
    38401 cacttttgca acttacgcag ggattgggtt ctggcgtatt aagaggtgag gaactgaatg
    38461 ctgtatttga gtcagcacct aatattatcc gctcgattgc cgattatctt gatgtcgaca
    38521 taggaaagat tcgaggtatg gcgagtgaag gaatgttaac agcagatatt gtaaaaaatt
    38581 ccttgcttgc agcagcagag cagactaata cggaatttga gaagatgcca cttacgatag
    38641 ggcagatatt tactagcata aaaaacaatg caataatgat atttggtgcc atacaaaaga
    38701 aaattgaaga tacagtatca agtaggggat tccgaacctt catagttaat ataactgatg
    38761 ctatatatgt tcttggaaat gttggatata gtgtcttcaa tgggttaatt gatttattta
    38821 gcagtccagc tttccagggc ttttttaatc taatgattgt tggagttagt atgattacgc
    38881 aaggactagg ttggataata acacaagcac taagtgttgc taacgtattt gcacagaatt
    38941 ggtcaattat ttcgcctgta atctatggta ttgtaggagc ttttattgct tacaaagtta
    39001 taatatattc agttttaata gcccaaacaa tttacacagc aattactttt acacagtgtt
    39061 ttgtgacagc gcttctcagt ggagaactat atgttgctac aaaagcaatg cttataaaca
    39121 agttaatgac tttaggagta agcagagcta atgtgacatt atgtgtgact atgattatgg
    39181 ttgtagctac aatagctcta gtaatagcag caattttcgt aggagtagca atatttaatc
    39241 atttcgcagg agctagtata agtgcgactg gagtagttgt aggagctttc tattttctag
    39301 gagcttgtat ttatgacgta ttcgcaggag cttggaatat tgtaatggca tttgcagagt
    39361 tctttgttaa ttcgtttaat attgttatct ataatgtaca gatgttattt tataaattcc
    39421 aaaattttgt aatagattct atgggtgacg ttggaggaag ttttgacaat tgtgctacag
    39481 ctttagcaaa tgcttttgta agtgcagcaa acatagcaat aaaagggatt aatggagtta
    39541 taaaagcttt aaatctaatc ccaggtgtta atataaatac tttaggaagc ttggacaaaa
    39601 tagattcttt tgtaaaacaa tataaagatt atcaaaaaac attaaaagag cctattaagc
    39661 cacaggactg gaaagctcca tatgcagaaa tcaaaaatcc atttgactct tacaaaaaag
    39721 ggtatgaagt aggtcaaaat ttagaaaata aattgaaaga tgcttttgac attaacaaaa
    39781 tagccgaaaa agcaaaaaaa gacttaagat tagacgattt atgggataaa aaatacggac
    39841 ttggtgatgg attgggttca gctggattaa actcaccttt gggcgatgca gcaaaaggag
    39901 caaaagatac cgcgggaaat actgcaaaga tggcaaagac tatggataaa agtcaagagg
    39961 acttaaaata cttaagagac atagcagaac aagaagtaat aaacaagtat acaggagtca
    40021 acattaaaat tgacatgaac aatacaaaca acataagtaa agatactgac ttagatggaa
    40081 tagttaatgt attaactgaa aaattaaacg acgccatggt tgtatcagca gaaggcgtag
    40141 tttagaaagg aggtgtaatc gtggcttatg atttttattt agatggagta caattaccaa
    40201 ttacacctgg caaattagaa ataaaaacaa caaataaaaa taaaactgta gaccttataa
    40261 atgatggaga agtaaacata ttaaagactc ctggtctatc tgaaataagt tttgaagcag
    40321 agtttacaca taataaatta cctttttgta gaggtcaatt tagagatgtt caattctttt
    40381 taagtaagct agaattacta aaaactgatt gtaagccatt tcaatttatt gtctcgaggg
    40441 aaatgggtgg aaaagtacta tttaacacta atataaaagt atctcttgaa gagtatgcta
    40501 tttcagaaga cgcagataat ggttcagata caaaagttgc aataaagtta aagcaatata
    40561 gagattattc aactaaaaag ttagttcctg ctcaacctaa aacaactaat gagactggca
    40621 gacctaatgt aaaaatagag cctaaaaggg tcgattcagt caatgcacca aatgctaaaa
    40681 catacacagt caaggcaggg gatagtcttt ggtcaatttg ccaaaaacag ttaggtaatg
    40741 gctcactgta taagaaggta tatgagttaa ataaaacaat gatggataaa gctaacaagg
    40801 gaaaaaaatt aagtaaatac accatctata aagggcaggt gttgaggctt gtctgatgat
    40861 ttagttctgg cgaatgatag agatataagg ctagttattg cacattggga agatttctac
    40921 gaacctgtag ttttggatgg tatcacatgg gaaatagaga gacgaggaac accatctaaa
    40981 cttgaattta caatagtcat ggatgatata ttagagtttt gtgaaggtaa ctctgtaaga
    41041 ctatattaca aaggtgtagg tatattctat ggatatatat ttcagaaaaa gagagataaa
    41101 gaaaatcata tcaagatagt tgcttatgac cagctaagat attttaagaa taaagatact
    41161 tatgtatata gtaataaaac agcaagtgaa cttgtaaaga tgttggctaa ggattttaaa
    41221 ttaaaataca atgtcataga agatacaaaa tataaaatat cgagagttga agaaaataaa
    41281 acactctttg atatggtctt aactgcacta gatgatactc taagagagaa aaaggaaatg
    41341 tatgttttat atgatgattt tggaagaata acattaaaga atgttgcttc tatgaaactt
    41401 gatacggtta tgaacaatga tgtaattgag gactttgact acaattcttc tattgatagt
    41461 gatacttaca caaagattaa acttgtgaga gataatgaag aaacaggaaa aagagatgtg
    41521 tatattgctc aagactcaac gcatatgagg agttggggaa tactacaact atttgataca
    41581 gttgataaaa atatgagtga agcagagata aaacaaaaat gtgatatact cctaaaacta
    41641 tataataaga aaactaagtc attaagttta aaaaatgtgt taggagatat tagagtaaga
    41701 gcaggttgtt tagtacctgt ttttttgtcg ttaggagata ttgatttaca aaattatatg
    41761 ttagttgaga aagtaaaaca tacatttgaa aataacagtc attttatgga cctaactttg
    41821 gttgatggag acgaatttgc ttcttattct tcatcaagtt atagtagtgg aaatactaat
    41881 aataaaaatg agaaacaaaa tggtcctgca caaagtacta caagtaaaga agatactgat
    41941 atggctaata agattaataa actacttaaa ggtaaattat caaatacagg aaatatattt
    42001 gttaaatatt caaatgctta taaagttaat ccagcactca tggctgctat atctatgcac
    42061 gaatcagcta gagggacttc aaatattgca aatactaaaa ataatttctt tggaatgaaa
    42121 aaaaatggag attacatgag tttttctagt gtagacgaag gaataaaaag aggtataagt
    42181 aatttatcaa gaaactatat ccatatagga cgaaaaactt tagaaagcat cagaaataaa
    42241 tattcttcta gttcagacaa agaatgggta aaatgtgtag gtgcatttta taagcaaata
    42301 acaggaagta cttataattc taatagtgca ggcacaggag ttggaagtaa tgaagaagca
    42361 gaaaagaatt taaaagattt aacttatcaa gttcaaaaca ataattctaa tacatcaaca
    42421 aacaataata ataaagtaag taaagttatt caagaagcaa aaaatcaact tggcaagcct
    42481 tacaaatggg gtggtaatgg tccaaagagt tttgactgta gtggtcttat ggtgtgggca
    42541 tttaaaagag gtgcaggaat aaatctcaaa agagtttcag cagaccaatc aaaagatagt
    42601 agaggaaaac tattatgtaa cataaatgat gtaaaagctg gtgatttagt attctttgca
    42661 tacaacaaag gaaaaggaaa tgtacatcat gttggactat atataggaaa tgaccaatat
    42721 attcatgctc cacaaactgg tgacgtagta aaaataagta gtttaagtgg tagacaaaag
    42781 aaaaagcatg attttgcaag agctagaaga ttcttttaag tgaggtgata aagtgtcaca
    42841 agaattattg caaataatta agaaggctgc aatggatgca gtagaaacaa gcaatccaat
    42901 gcaaattgca tttggaacta tagaaagtgt taatcctttg atagttaaga tagaacaaaa
    42961 agcatctttt gaagaatttt ttctaataca aacagagact tttaaaagat atacagataa
    43021 aaaaataggg gataaattag tcttaattag gatgcaagga ggacagcaat atttgatttt
    43081 agataggatg tgatgaaatg ttaccaacag ataacattga ctatgatata gaagatgtat
    43141 cgataattaa ttttgatgtt agacaagaac caagtaagac gtttaaattg aatatagaga
    43201 aaaatagagt agatggtatt tgtgatgatg tagaagcatt aaaacaaacc atttttttaa
    43261 ttttaaatac tgaaaggtat gagcacctta tttattctag aaattatggt gttgaattaa
    43321 atgatttaat tggagaacct atttcatatg taatacccga acttgaaaga aggataacag
    43381 aagcactaat tcaagatgat aggattgaaa atatagataa ttttgagttt caaaatataa
    43441 agggtaaagt acaatgtaga ttttcagttc atacaaaata tggaaatata aaagcagaga
    43501 aggtggtgag tgtataattg tttgagttaa tgacatttga aaatataatt aaaagaatgt
    43561 tagatagtgt accagatact tttgataaaa gggaaggttc tataatatat aatgctcttg
    43621 ctcctgttgc tatagaactt acagaaacat acattgctat ggatgaatta ctagaccaaa
    43681 cattcgtaga tactgctagt tattattatt tagagaagag atgtaaagag agaggtatta
    43741 caccacttga agccactaat acaattgcaa aaggagtttt taacatagat attcctattg
    43801 attctaggtt taatctagga gaatataact atgtagcaat tgagagaata tctgaaggta
    43861 tatataagat gaaatgtgag actgcgggac ctatttttga gttgggacaa ctaataccta
    43921 tcgaatatat agacaaatta gaaacagcag aactgacaga aatactgata aatggagaag
    43981 atgaagagag tgaggatagt ttaagacaaa gatattatga tagcctaaat tcacagagct
    44041 ttggtggaaa tatgcaaaat tataaagatg aagttaacaa aatacaagat gttggaggag
    44101 ttaaggttta tcctgtgtgg gacggtggag gaactgttaa gttagtaata attaactcta
    44161 atttcaaagt accatcagag gatttagtta atttagtgca agaagaaatt gacccaattg
    44221 gacatcaagg acaaggctta ggattagcac caatagggca taaagttact gttacaggtg
    44281 ttgtaagtac aactataaat atatcagcag agataacata caaaaatggc tacacttggg
    44341 agaatataaa atcaattgca gaagaagcaa tagacgacta tttaaatgaa cttaacatga
    44401 gttgggaaga tgaagaaaac ttaatagtcc gtatatctca aattgaaact agattactta
    44461 gtattgatgg agtattagac attgcaaata caatgataaa tgaggttaaa tctaatctaa
    44521 caataaatag taacagtata gtagtgagag gtgaggtagt tggataaaga gattaatcta
    44581 ataaattact taccacaaat tctacaagat aaagaagaat atataaaagt atttaatgta
    44641 ggaaataaag aaataaaaat attacatgat aaattaaagg acctatcaaa tgaccagttt
    44701 ttagaggacc taactataag tggtataaaa agatgggaaa agataatgtc tataactcct
    44761 aaaagtaatg agagtttaga agatagaagg tttaggattt ttagtaaata tataagtaaa
    44821 ttaccttact cagagagatt tttaaggaat tggctagata gtatagttgg agaaggtaat
    44881 tatgagttaa ctattaataa tgctacttat aatatacatc ttgaaagtga tgctagaaat
    44941 caagattggt ttgaggaagt tcattctttt gtaagtaata ttaagccatg taatatgact
    45001 ttagattaca ctagagtgct tataagcaaa gacaattata tgaattttgg tataacaacc
    45061 ctaatgggtc aagaaataac tatataccct tggagtccac cagatataga aacttatgga
    45121 gaaattgatg tattaactgg caatggagtt ggataccaag agataacaat attttaggag
    45181 gtgatatatt ggctatagat aaaagttatt acactataat tacagatgta ggaaaagcaa
    45241 agatagcaaa tgcaagtgtc acaggtaata aagtgggatt tgtaaaaatt caacttggtg
    45301 atggaggagg gagtgaatat actccaactg agagtcagac agctctcaaa aacgtggtat
    45361 gggaaggcaa tattggaaat acaactacag atgaaactgc accaaattgt ataatattag
    45421 agagtttaat accatcaagt gtaggcggat ttatgataag agaaatagga tatttagatg
    45481 atgaaaataa tttaattgcc atttctaaat acaaagagtg ttataaacct tctatagaac
    45541 aaggtgcagt ggtagacatg aaggttaaaa ctgtgcttat tgtatctaat gtaaataata
    45601 tagaacttaa aattgaccca acaataatct ttgcaacact caaagatata caagacttag
    45661 aaactaaaat aggtactgtt aatactaaaa tagatacaac taaaacagaa ttaacaaata
    45721 atttagaaac tgctaaaaca gagttaaata ctagaattga cacagaaaat gagaaacaaa
    45781 atattaaaat tgaccaactt attgcaggtg gctctaatgt ggcatctact caaacaataa
    45841 caattgacga ttgggttgag gatgcagaaa atggattcaa agcaactgta acacatagtt
    45901 tattaacaca gagaatagtt gtaaatatta tagatgttac tacaaaagaa aatgtagtta
    45961 caaactttaa aattatagat gataattcta tagaaattag aagtgaagta aaagctgagt
    46021 taaacgttta tgtgataaat ggaaatgcag aaactcattt tattaatgcg actgtggatg
    46081 ataacagagt gtctgaaatg actacttatt cgtctaagaa aatcgaggat agattgatta
    46141 atatagaaga aaaagtaaat ggtggtttat ctagtattgc aacaagtgta aatgagttga
    46201 taacttattg ttaaaggaga gtgagaaaat gcagacagaa tggaactttg ggtacaatgg
    46261 ttcgccacaa agtgttatat tgaaacctgg caaatataaa tttgaatgct ggggttcttc
    46321 tggaggtatc aacaattctt cttggtatac tgatgctaaa ggcggatatt ctaaaggtga
    46381 aattacatta aaaaaacaaa ctacattata tgtttacgtc ggcgaaagtg gttttgcttc
    46441 ttcatctacg agtaataaca ctaaaagtgg ttttaatggc ggtggtaaag gttatttaaa
    46501 tcaacagatt atgggtactt attattctat gtacggtggt ggtgctaccg atataagact
    46561 tgttggtggt gcttgggata atgagcaagg tttgctatct cgtataattg tcgcaggtgg
    46621 tggcggaggt tcatattatc cttccactgg tggtgcagga ggaggattag aaggaggtac
    46681 tgggtatagt tctaatgaca gataccgtcc cggtggtact caatatcaag gtggtattgg
    46741 tcgtgtaaat acagaaaacg gaagttttgg aaaagggtgt tctgttaaag attcaactgg
    46801 cgaaggcggc ggaggtggct ggtttggtgg tgcaggcatg aatggtgtag gagcaggtgg
    46861 aggtggaagt agttatgtat tgactaaaga cagttataag cctactggct acacaccaac
    46921 atctgaatat tattttgata atattgttat gacaccgggt ggaaatactg ctggtgctta
    46981 tggttacgca caaataactt tacttcaatc attaccattt ttaaatatat catcttataa
    47041 ttctacacaa gcaacattca aagctgacca cactgaccct actttattga ctaagataga
    47101 atattttata gatgatgtat taaaagaaac tataacaaca gatttaacag aagaaaaaac
    47161 aattaactat acactagaag ataatgcact acacacactt aaaatagttg ttacagacag
    47221 taataatgct acagcagaaa aagctgtcag tataagtaag aatataatgc cattgcccga
    47281 aaatgttaat ttaaatgata tatctactaa actagttgaa gttaatgcag gatttaagac
    47341 tggtaaaaca agtattataa acactttggc actaaagaat atagaagcaa gtttaaataa
    47401 cacattagtc gagttgtcag agaaaataaa aacaagtttt gatagttcag acgctagtgt
    47461 acaggatttg atgaaccagt taacacaagc taataacact ataagtcagt taaattctaa
    47521 atataaagtt gctagtggca atagtgttgt taattattgt actaatacaa aaggatttta
    47581 ttttaatagt gactatctgt tcctatttcc tggagccatt caaattaacg gacttaattt
    47641 tgttcctaat atatttttta ctacttttga attaattgat gatggttatt ttcataaata
    47701 ttttgttttt gcttgtcgtg gtattttcac tcaagatttt gtaattactg ctcattatta
    47761 tcgtctaaca tcatatttac aagattttaa agttggaggt gaggttctta aattaaatga
    47821 acgtgatgtt tatatggata atagaggtat acaacttcct tgttcaagac aaggttcttc
    47881 ttttaaatgg caagctataa aatttattta ataaatgagg tgataaaatg gatagagcaa
    47941 atagaataat ttacgaccag acaggcaaaa tactgctaca gacaggggaa gcaacaggag
    48001 atatactaga acatgataca ataacagaat tacattatat tgatgttgag tatggaagta
    48061 tagactatac aagaaataga attataggta taaatataga aacaaaagaa ccaattttag
    48121 aagaaatacc agtatttatc tcggaggaag aaaaaagaat acaagagtta gaaaatcaaa
    48181 ttttattaaa tgaaaataag aaagtaggag gaattttata atgaatataa ataatgttgt
    48241 ggtaagaata ttagcagaga gaatattaaa cggaggctta aaccctttaa aaaatcgaga
    48301 atttgaactg gatgatgtaa ctaatgcaga atacagaaaa gcagtagagg attatataat
    48361 tagagaaagt ggagtagtcg aagaagcaga accaactata tagagggttc ttttttattg
    48421 aaagaaggtg actaaatgac ttttaaagag ttagttaata aagttagaaa tcttgtatta
    48481 gaagcaaaga atgtaactat agaagataca gaaaataact ttacaagtga taatgtagaa
    48541 ggagcattga aagaggtttt tcaaaatgga gttaatgcta aaagtaatgt agtaacagca
    48601 ttaaactcca aaggtgcaga tgttactaca agcgatacat gggaagaaat aaagaataaa
    48661 attgatataa aagaggggag attagattta agagaaacaa cactttcaaa taactattcg
    48721 tatttagtta caaatggagc tataaaatat attgaaagat gtagtgggaa cttcaaaact
    48781 tttgaatatg aagaaccata tttttatgta attaaagaaa ctcatctaat taaaattaat
    48841 gctattgatg aaacagtagt ttttgacatt actttagcta atgctaactt ctcatgtatc
    48901 tgtgttactc aagagtattt atttatatct gacaatacta aattatataa aataaacaag
    48961 ataacaggaa ttgaagtgca gtcaatagaa ggtgcttatt ataagttatg tacttatggg
    49021 gaatttattt atggagtata tggagatgag acttcttcta cacttcataa aattagaata
    49081 tctgatatgt atataatgct aactaaaaat ttagtttcta atggtattta caattttaaa
    49141 ggaggtaagt ttgtttgcaa taagaatgct atttatgcta caacagaaca ctcaaattca
    49201 agtagtatta caacatgtca tttatctaaa ataaattttg attttgccat tgctaaagat
    49261 tttagaattg gaggatattt gcatatgaaa aacattaagt ttttaaatga ttttgttatt
    49321 gtatctgatg cagaaagagg tatagaaatt gatagcaaca aaaaaagtgc tttagtaaaa
    49381 tatgacgcaa atttaaattt aattgtgtat tcagacgata acaaatatga caattttgat
    49441 atatataatg gatatatata tgctatatat tcgctttcta gtagtccttt tgtaaaaata
    49501 agtttaaata ctcttaaaca tatcgacagc taccgaaaac ttactgaaac atacccaaat
    49561 gctggtatgt ttgtaataaa tgatatagtt ttctttatta gtagtggaat ttttagaaat
    49621 atattgtcaa aaaaggttta ttcggatgag aaaggagaat cattatgatt tatttaggaa
    49681 atttaatgga tacagaagaa caaaatataa aatatgttgg tatgatacac tatgaaccaa
    49741 atttgttatc ggaggaaaac ttaaaacaag gtattttgat agagagttta ccaactcaaa
    49801 agtatgcaga gaataaagaa gcaaagctat ttataaatat agatactaaa gaggttttct
    49861 atagatatac agatattaaa agtaacatag aagataaagt aaattctaca gaacaaacaa
    49921 tagcagattt aacatttcaa ttaatgagta atggggtgat atagtatgaa ttggtataag
    49981 ataatagcag atttctataa taatggtaat tggactaaag agcaagttaa aacagcagta
    50041 gaaaagaata agataacagc aagtgaatat aaagaaataa caggagagga ctatatagca
    50101 tagtcttttt taattcaaaa attaggaggt tttcatgaat gaagaacttt tcgaagcaga
    50161 tttaaaaaga catgaaacaa gaataaataa acatggagaa gaaatagacg aattaaaaat
    50221 agcaaatata gagtctaaag cagaattaaa agcattgtgt gagaatctaa actcacttac
    50281 aagtatgctc aaatggctaa ttggtacaat gattacaaca cttatagggt tctttatatt
    50341 tgcaatacaa agaggaatat tttaattagg aggataaaag atggataatt taataagttt
    50401 tataccagag cagttgctaa ttttagtggc tgctctctct attataggta aaggttgtaa
    50461 aaaatataaa caattagata ataaatatat tccaattata ttacttgtgt tgggaatcgg
    50521 attttctatt tggatgctag ggcttagtcc taacgcagtc ttacagggaa taatttgttg
    50581 gggaatatca ataggtataa atcaaactta caaacagttg aaggaggaaa ataaataatg
    50641 aaaatatgta taacagtagg acacagtatt ttaaaaagtg gagcatgtac ttctgctgat
    50701 ggagtagtta acgagtatca atacaacaaa tctcttgcac cagtattagc agatacattt
    50761 agaaaagaag ggcataaggt agatgtaata atatgcccag aaaagcagtt taaaactaag
    50821 aatgaagaaa agtcttataa aatacctaga gttaatagtg gaggatatga tttacttata
    50881 gagttacatt taaatgcaag taacggtcaa ggtaaaggtt cagaagtcct atattatagt
    50941 aataaaggct tagagtatgc aactagaata tgtgataaac taggtacagt atttaaaaat
    51001 agaggtgcta aattagataa aagattatat atcttaaata gttcaaagcc tacagcagta
    51061 ttaattgaaa gtttcttctg tgataataaa gaagattatg ataaagctaa gaaactaggt
    51121 catgaaggta ttgctaagtt aattgtagaa ggtgtattaa ataaaaatat aaataatgag
    51181 ggagttaaac agatgtacaa acatacaatt gtttatgatg gagaagttga caaaatctct
    51241 gcaactgtag ttggttgggg ttataatgat gggaaaatac tgatatgtga tataaaagat
    51301 tacgtgccag gtcagacgca aaatctttat gttgtaggag gtggcgcatg tgaaaagata
    51361 agttctatta ctaaagaaaa atttattatg ataaaaggta atgatagatt tgatacactt
    51421 tataaagcat tggattttat taatagatag ataaaagtta tcaactagaa gtggttgttt
    51481 gttgtgataa ctctattatt gtaatataat gtaaatatat tattgtgata atggaggatt
    51541 tatgtatgga tgcattggtt tatgagagat ttgtaagagc agcttttagt attaaactta
    51601 ataacttgat taatagaagc gaagatttag gtggattggc tgaagctgat atctttagag
    51661 cagcaaataa tttacatgaa ttaaatgaga taaaaatagg tactgggtat gctattgcaa
    51721 tatttaataa tgagatatta gagtcttgta atgtttctga taatgatagc aatagaatga
    51781 ttgaactatt tgatagaagt ttaattgcaa cttctaggga ggaaatattg gatattataa
    51841 gagaatatga aacttataga ggacgatatc ttacttttaa ttggaagaga tagaatgttt
    51901 aagttaggaa gtagtaatta tagttagtta ttactttctt tcacatattt ttattatttc
    51961 aataagatta tttccaaata ataatttatt caatgataat aagtagaaaa taaaattttg
    52021 aatcaatata aaatttaatg aaatgaggta gtaaaatcat ggataaaaaa atagacatag
    52081 cgaagtttat agtaaataga attgattact atattgaaaa atcagataat aaagctagtt
    52141 ttttactatt attaaatagt gcaattatag gttttttatt ttcagggaag gaaaaaataa
    52201 tgaatcactt aagtataagt aatatcagat gtttagagat gctattttac attgttatat
    52261 tatgtatatt tgttatttca atttattttt cgattatggt tttaaagcca aggaattcta
    52321 aaatagaaaa tgaatataaa tctatttttt attataaaga gatagcatct ttaaataatg
    52381 aacagtacaa agaagcattt gaaaatgcat ttaaagacga agaaaacttg attaatgatg
    52441 cacttgttca aataaaagaa ttatctttaa tctgtgataa gaaaatgtat aatgtaaaaa
    52501 agtcagtaga agcttttatt ttaggtggta ttatattgtt tatatatata cttgtagtag
    52561 tttttaatgc tatttagaaa atgttttatt tggttagtat tcctctatga agatagaatc
    52621 aaatcataga agaatactat ttacatattt gtagattctt gtaattgatt ttcatttaat
    52681 tttttaaatg ctagttttaa agtttcttta aaatcaggta ctgtgttttc attaaaatct
    52741 tcaagttcat cctctcctat ccatgcaagt tcattatgtt ttgatgtggg ttcaaattta
    52801 gaaatatcat aatcatttat tatttctgcg agagttataa tgcctttgtg taaaccatca
    52861 ctttttttaa cttgataaat tgctagaggt ataggttggc aatcatcttt tcttgtgcaa
    52921 tcagtaatag gttcaatgtt tatattaaaa tctttttcat attcatcttt aatagtattt
    52981 ataattgaag tttctagact tgccttagca caaccaaatt cccatttact cgcattatta
    53041 tttctattat cacttctttt cgcaattaat atttttgaag ttgatttatt ataacaaacc
    53101 gcaacacagt gtaattccat taaatctact tttatatagt ctttatctat tgtattttta
    53161 tcataactgg ggtttgtttt agaaattacg tcacctattt tttcaatctt atcactaagg
    53221 tttctgtcta taagtatttt atccaaagcc ttgtctacag aattaaacat aaaagaatca
    53281 attagtaatt tactttctcc ttttttatta aaaaaatatt ctcgaaccaa ttcattttct
    53341 tctatttcat caaaagaaaa actatcatca aattct
//
LOCUS       DAEPKC010000015        52905 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.015, whole genome shotgun sequence.
ACCESSION   DAEPKC010000015 DAEPKC010000000
VERSION     DAEPKC010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 52905)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52905)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52905
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.015"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(<1..884)
                     /locus_tag="KR294_001006"
     CDS             complement(<1..884)
                     /locus_tag="KR294_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009243519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HBH0239110.1"
                     /translation="MKLKHIAIIGSLFPILFSLVLFFGVLISADSDDENSNFSSGITG
                     MNLSAEVLKHQTMVEKYARENGISEYVNVLLAIIQVESGGTAEDVMQSSESLGLPPSS
                     LDTESSIKQGCKYFASLLSSCKNQDIDDLNVAIQSYNYGGGYVGYVAGNGKKHTFNLA
                     ESFAREKSGGKKVTYTNPIAVAKNGGWRYGYGNMFYVELVNQYLTVPQVSGELAQKVM
                     NEALKYQGWKYVFGGSSPTTSFDCSGLTQWCYGKAGISLPRTAQAQYDATQHLPLSQA
                     KAGDLVFFHSTYNAGSYVT"
     gene            complement(881..3085)
                     /locus_tag="KR294_001007"
     CDS             complement(881..3085)
                     /locus_tag="KR294_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH0239111.1"
                     /translation="MKERIQSAFTKRKILHFLKMALFVVALSLILLSLLGTVAHATGL
                     VDDTINAENLYSKYPLSNYQLDFFVDNSWSWLPWNWLDGIGKSVQYGLYCITNFVWTI
                     SLYLSNATGYVVQEAYKLDFINDMADSIGKSIQTLAGVTENGFSSTGFYVGFLLLIIL
                     VVGMYVAYTGLIKRETSKALHAVINFVVVFVLSASFIAYAPDYIKKINEFSSDISTAS
                     LDLGTKIMLPNSDSEGKDSVDLIRDSLFSIQVQQPWLLLQFGNSNAEEIGTDRVEALV
                     SASPEDEDGKTREEVVKTEIEDNDNNNLTIPQVVNRLGMVFFLLFFNLGITIFVFLLT
                     GMMLFSQILFIIFAMFLPISFLLSMIPSYESMAKQAIVRVFNTIMTRAGITLIVTVAF
                     SISSMFYNISTDYPFFMVAFLQIVCFAGIYMKLGDLMSMFSLNAGDSQSMGRRIFRRP
                     YLFMRHRARRMEHRIARAVSAGGISGGVAGAVAGSAVAGKRAERKNTASKENRGNTTS
                     SMGQRAGSKVGAVLDTKNKVKDKANAVKENIKDMPTQTAYAVYSAKEKAKSSVSDFKR
                     GMVQEQQSRQTGRLEKQEQHKKSIAVKRMELQKAQEARQAQRKADGSATTGATRPHER
                     PATASTVSKTGAEKMQEVKRPATTPTTKASEPVKTSGVKERPLSSSTPDGKATQSTYR
                     QNVEKVTVSKETRQNYTKDRRTKVQQTQTVQKNQQTTEKIRNLVTKKGQKKK"
     gene            complement(3085..5535)
                     /locus_tag="KR294_001008"
     CDS             complement(3085..5535)
                     /locus_tag="KR294_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH0239112.1"
                     /translation="MFPIKYIDNNLVWNKDNEVFAYYEMIPYNYSFLSAEQKFIVHDS
                     FRQLIAQSREGKIHALQIATESSIRSMQEQSKKLVTGKLREVAVQKIDEQTEALVSMI
                     GDNQVDYRFFLGFKLMVTEEQLNLKNIKKSAWLTFKEFLHEVNHTLMNDFVSMPNDEI
                     NRYMKMEKLLENKISRRFKVRRLEIHDFGYLMEHLYGRDGIAYEDYEYQLPKKKLKKE
                     TLIKYYDLIRPTRCVIEESQRYLRLEHEDKESYVSYFTVNVIVGELDFPSSEIFYFQQ
                     QQFTFPVDTSMNVEIVENRKALTTVRNKKKELKDLDNHAYQAGSETSSNVVDALDSVD
                     ELETDLDQSKESMYKLSYVIRVSAPDLDELKRRCDEVKDFYDDLNVKLVRPAGDMLGL
                     HSEFLPASKRYINDYVQYVKSDFLAGLGFGATQQLGENTGIYMGYSVDTGRNVYLQPS
                     LASQGVKGTVTNALASAFVGSLGGGKSFCNNLLVYYAVLFGGQALLLDPKSERGNWKE
                     TLPEIAHEINIVNLTSDKDNAGLLDPFVIMKNVKDAESLAIDILTFLTGISSRDGEKF
                     PVLRKAVRSVTQSENRGLLHVIEELRKEDTAISRNIADHIDSFTDYDFAHLLFSDGTV
                     ENAISLDNQLNIIQVADLVLPDKDTTFEEYTTIELLSVSMLIVISTFALDFIHSDRSI
                     FKIVDLDEAWAFLNVAQGETLSNKLVRAGRAMQAGVYFVTQSAYDVSKESLKNNIGLK
                     FAFRSTDINEIKQTLEFFGIDKDDENNQKRLRDLENGQCLLQDLYGRVGVVQIHPVFE
                     ELLHAFDTRPPVQRNEVE"
     gene            complement(5513..5911)
                     /locus_tag="KR294_001009"
     CDS             complement(5513..5911)
                     /locus_tag="KR294_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009274602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBH0239113.1"
                     /translation="MKKIKSYTGIWNVEKVLYAINDFNLPFPVTFTQITWFVITEFII
                     ILFGDMPPLSMIEGAFLKYFGIPVALTWFMSQKTFDGKKPYSFLKSQITYALRPKITY
                     AGKAVKLHKQILNETITAVRSVNYVPDKIY"
     gene            complement(6029..6532)
                     /locus_tag="KR294_001010"
     CDS             complement(6029..6532)
                     /locus_tag="KR294_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBH0239114.1"
                     /translation="MIDDMAVYIANLGRYNEGYLVGAWFTFPIDEEDVKEKIGLNEQY
                     EEYAVHDTDNFPIDIGEYVSIEELNEMYEMIEELPDYIVECLDEFISHYGTLEEVVEH
                     KDDIYFYPDCETMTDVAYYYIDELNALGDIPANLQNYIDYEAYGRDLDMGGRFIETSR
                     GICEIPY"
     gene            complement(6550..7053)
                     /locus_tag="KR294_001011"
     CDS             complement(6550..7053)
                     /locus_tag="KR294_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBH0239115.1"
                     /translation="MQETRVLVETGRTNGEETTSYWFDLPIDVAEFEEKLGVGAESQD
                     YRIIEKVLPYADEVHEHTSVYQLNELDFMYRQLSADMQEEYVELLTVFENLEALYICR
                     NVITVYHDCKSMIDVARQKLMNDPTFKHLSEDCQAYYFDFEAYASHLLENKRYLVTEN
                     SIFELPE"
     gene            complement(6972..7268)
                     /locus_tag="KR294_001012"
     CDS             complement(6972..7268)
                     /locus_tag="KR294_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005339688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBH0239116.1"
                     /translation="MNDIFKDMQAKVGCEYISDLPSYKRKVWHEMKRLNPADYEEKQL
                     KDFSKYVFGMSYQTLKDVMKQQKGREEQCRKQGYWWKREEQMAKKQHHTGLTYR"
     gene            complement(7367..8161)
                     /locus_tag="KR294_001013"
     CDS             complement(7367..8161)
                     /locus_tag="KR294_001013"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239117.1"
                     /translation="MGTINYFLKGIKVLMISDEMRVDILHAVFINKNFIKDEENCNYE
                     KYLLELVNKSIYFREKSNFAEYVPPKSENHGECDCNSPNYQMDFKLLESTTRLHASKE
                     LTGQIQKFCDGVIGKCPPRRPNTQMTVTRLFASLRDYDCESLHSCLTEKYEYGTIEFD
                     IQTYVKLLTFKKNLFFFFPYKFSFNTCYNFKYALDSIRIALEKDFRESNLFREKYYAE
                     YDTFLAYIYEDNLIISKFEQDGKLQMIDCIYLFKSQTYSKLYEYTW"
     gene            complement(8200..8421)
                     /locus_tag="KR294_001014"
     CDS             complement(8200..8421)
                     /locus_tag="KR294_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239118.1"
                     /translation="MNFGQNLYQWFLSNAQSLVLMAIVVIGIYLGFKREFSKLIGFLV
                     VALIAVGLVFNAGGVKDVLLELFNKIIGA"
     gene            complement(8422..8556)
                     /locus_tag="KR294_001015"
     CDS             complement(8422..8556)
                     /locus_tag="KR294_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017143882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HBH0239119.1"
                     /translation="MWELVKDFLLVSMGMGIGVVLMCILSISKEADYEMKQLEESEDN
                     "
     gene            complement(8569..9765)
                     /locus_tag="KR294_001016"
     CDS             complement(8569..9765)
                     /locus_tag="KR294_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HBH0239120.1"
                     /translation="MVLNEEQWIKELREKRIAYGISQGRLAVASGITREYLNKIESGK
                     MKPSKELLETLHKELARFNPEAPLTMLFDYVKIRFPTLDIQHIIKDILKLNINYMLHE
                     DYGHYSYTEHYSLGDIFIYTSADEEKGVLLELKGRGCRQFESYLLAQQRSWYDFLMDA
                     LIDGGIMKRIDLAINDHTGILDIPELAEKCRKREYIGKSRSYKYYQSGELIKHREDDR
                     EYMGSTLYLGSLKSDVYFCIYEKDYEQYVKLGTPLEEADIINRFEIRLRNERAYYAVR
                     DLLTYYDAEQTAFSIINQYVRFIDEEPDKRKNDWKLNDRWAWFIGDNRQSLKLTTKPE
                     PYTLDRTLRWVQRQVAPTLKMLKKIDKGNGTDYMETIEKQAILSEKHEMIIKQQTTPA
                     KDLVES"
     gene            complement(9950..11344)
                     /locus_tag="KR294_001017"
     CDS             complement(9950..11344)
                     /locus_tag="KR294_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008787614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH0239121.1"
                     /translation="MRMILNKGHRIRASDKNLVYRFSMGTLLFVFVAVILLLNTKQLM
                     RTDWEHFSLLDNGFTLSLYNFITILIATGVCALVAFLYYRFCYDSFKKLLHRQKLARM
                     ILENKWYEADTVQDSVFFTDLQSRSREKIVWFPKIYYQMEKGLLHIRCEITLGKYQDQ
                     LLRLEDKLESGLYCELTDKTLHDGYIEYTLLYDMIANRITIDEVRAENGCLRLMKNLV
                     WEYDALPHALIAGGTGGGKTYFLLTLIEALLHTNAVLYILDPKNADLADLGTVMGNVY
                     HTKEEMIDCVNAFYEGMVQRSEQMKRHPNYKTGENYAYLGLPPCFLIFDEYVAFFEML
                     GTKESVGLLSQLKKIVMLGRQAGYFLIVACQRPDAKYFSDGIRDNFNLRVGLGRISEL
                     GYGMLFGSDVKKQFFQKRIKGRGYCDVGTSVISEFYTPLVPKGHDFLQTIGFLAQARQ
                     DGTATCEAKGDGSD"
     gene            complement(11438..11875)
                     /locus_tag="KR294_001018"
     CDS             complement(11438..11875)
                     /locus_tag="KR294_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004056026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239122.1"
                     /translation="MCEECYSDENRITPLLNPLDCLENHTQYICGTCGRCICIEHDPN
                     RGLQRWNFPFKSLEIAKLYLRTADYTTKSSCGIYEIENSKGRVSYKIFAGNEDLHLFL
                     KKNKDKKCKQMTPVFNVGEYKEYPHTEVRKLTSDEIKQYMSER"
     gene            complement(11977..12360)
                     /locus_tag="KR294_001019"
     CDS             complement(11977..12360)
                     /locus_tag="KR294_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009588269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBH0239123.1"
                     /translation="MRLSNGFVIDKEKTFGELKFTAVRDVFLQNEDGTPSTQLKKRIY
                     DLKCSLHGGIIPVSVPPEVPLREFPYNAVVELVNPVADTVSRKTYTGADVDWYVKAED
                     IVLKNKGNQNTGTSQNHTPQGQPKK"
     gene            complement(12376..12702)
                     /locus_tag="KR294_001020"
     CDS             complement(12376..12702)
                     /locus_tag="KR294_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBH0239124.1"
                     /translation="MEMKYVVPDMAQSFGTLEFAGESEPIFERDKNNRKVIARRSYNL
                     YSDVQKGENVVVEIPVQAGEKHFKYEQKVKLVNPKLYGRGYAIGDVGHTDYVLVADDI
                     VAVEEK"
     gene            complement(12828..15872)
                     /locus_tag="KR294_001021"
     CDS             complement(12828..15872)
                     /locus_tag="KR294_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SrtB-anchored collagen-binding adhesin"
                     /protein_id="HBH0239125.1"
                     /translation="MKKILKRLCTGVLAFATVVTALPSTAVHAESKQYWTESEERVGI
                     VEKVMNDGSIGSTFNEGHLTVEGEDAYCIDINTDFKNGYKTRADASTRMSADQISDVA
                     LSLEYVKQYGEAHKELNYKQVYLLEQCVVWQRLSVHLGWQCDNVRASYDEIPKATQDE
                     VFAGAKAFVKENKGRYECGGYIYSGEGQELGQFWAKLNVGNAKLQKTSSNTSITDGNG
                     NYSIAGATYGVFSDKDCTKQLATLTTDKNGNTDVVEVKAGTVYIRELSAPAGYKVDTT
                     VYSLKVEAGKTATLNVSDTPKVTDTLIELFKIDMETQKDNPQGNASLEGAEFTWKYYA
                     GFYNKDNLPAEATRTWVTKTIAETDSDGTTHYITKLADAYKVSGDSFYMQDGKAILPL
                     GTLSVEETKAPNGYLLDGAYMQAGDKSEQIKGLYLTQITEDGDLAVLTGSNQFSVSDK
                     VIRGGVKIQKRDLETSDTKPQGSATLKDTAFDVISLNDNSVLVEGKLYKKNEVVKTIR
                     TDIEGVASTSADLLPYGKFRIVESEAPDGYLTDGAKPIDFAITENGKIVDLTDEAHSI
                     YNQIKRGDIEGVKIGAGTHKRLADVPFRITSKTTGESHVVVTDDNGQFSTSAEWTSHK
                     HNTNAGKTSEDGVWFGTSEADDSKGALPYDTYIIEEMRCDSNKGFELIPPFEIVVSRN
                     NLVIDLGTLTDEYEKEISIHTTATSKDSEKTILAGKEVTIVDTVKLDGLTKGTKYQLK
                     GWQMLKEENAELIIDGKRVENDYTFIADDEEMKVEISYTFNASELGGKNLVTFEELYD
                     LSNPDEPVKVAEHKDIEDDGQTVLITERIIKIHTTATDKDGNKEIEAGKDVTIIDTVT
                     LEGLEVGTQYKLVGWQMLKEENAELLINGKRVESDYTFTADSETMKAEVAFTFDATSL
                     DGKQLVTFEELYDLSNPDEPKKVTEHKDIEDEGQTITFNEKPEVPEKLETPQTPEKPN
                     RPSDSPKTGDSTNVMAFLVMLLTSAGGLAGTYLYKRRTMKKS"
     gene            complement(16115..17479)
                     /gene="rlmD"
                     /locus_tag="KR294_001022"
     CDS             complement(16115..17479)
                     /gene="rlmD"
                     /locus_tag="KR294_001022"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HBH0239126.1"
                     /translation="MLSKNEMYIVDIVDIGQGGVGVGKYNGITVFVEGGLIHDKVKVR
                     INKVKKNYAVGDIVEIIEKSPFRVKRVCSDNLRDCGGCQIQDLDYNKQLEMKTNEVKQ
                     VLSRIGKLEDVEVHDTIGMDNPYRYRNKAQFPIQKNNGIPIIGFYKKKTHDVISTEKC
                     VIQHEINDKIVKIIKTYIRAYKVSIYDEKTHTGLIRHLVTKIGFTTKEVMVVLVANGN
                     KLPYLKELASVLKENIPGFKTLVVNVNQKDTNAILGRENIVIYGDGKINDYIGDLVFE
                     ISPLSFFQVNPVQTKVLYDKALEYANLNDTDTVFDIYCGIGTISLFLAQKAKKVYGIE
                     IIDDAIKDAKINAKLNNIHNAEFYVGKAEEIVPKMYREGKTANVVVVDPPRKGCDEKV
                     LETIVSMNPERIVYVSCNPSTLARDLDYLNVHGFKCVEAQPVDMFPHSTHIETCVLLQ
                     RRTM"
     gene            complement(17654..19414)
                     /gene="pyk"
                     /locus_tag="KR294_001023"
     CDS             complement(17654..19414)
                     /gene="pyk"
                     /locus_tag="KR294_001023"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HBH0239127.1"
                     /translation="MLNNVKKTKIVCTLGPASQSEEVLTQLMQNGLNVCRFNFSHGSH
                     EEHKERIDMAKKVREKLNKPVAILLDTKGPEIRTGNFEDPEVFLEEGQKFTITMKDIM
                     GTKEMCTVSYKGLAEDVKSGDSILIDDGLVGLRVKEINGEDIVCVVENSGIVKNHKGV
                     NVPGVKINLPAITPKDISDIEFGISQGIDYIAASFVRKASDVLAIREVLENNNATDIQ
                     IISKIENQEGVENLDEILKVSDGIMVARGDLGVEIPTEEMPIVQKMMIKKCNELAKPV
                     VTATQMLDSMIRNPRPTRAEVTDVANAIYDGTDAIMLSGETAAGKYPVEAVKMMATIA
                     KRTEETLDYDRLLKENGTNNVTVTDAISHATCTTAVDLNASAIITSTSSGYTARMVSK
                     FRPKSPIIATTNNEKTMNKLALTWGVYPVKSSVAGNTDEVIEKAIEAARQADYIDNGE
                     LVVITAGVPVGVSGTTNLIKVHVISEEIVQGIGVGTQTVEGKVRIIKNGNACVDFNEG
                     DILVSTATDAEMNNYIEKAGAVVTENGGMTSHTAIVGINLDIPVIVSAADITNLVKDG
                     EVVTVDASRGVVYRGSTRVL"
     gene            complement(19466..20425)
                     /gene="pfkA"
                     /locus_tag="KR294_001024"
     CDS             complement(19466..20425)
                     /gene="pfkA"
                     /locus_tag="KR294_001024"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HBH0239128.1"
                     /translation="MKTIGLLTSGGDAPGMNAAIRAVVRSAIYYGCKVYGINRGYKGL
                     LEEDLTEMNLSSVGDIIHRGGTILKSSRCEEFKTEEGRLKAVKILKKYKIDCLVVIGG
                     DGSFAGAQKLSDLGFPAIGIPGTIDNDLAYTDYTIGFDTAMNTIIDAIGKIRDTSSSH
                     ERVNIVEVMGRHCGDLALYAGLAGGAETIIVPEVEITVDEVALRLKTTQKRGKRHSII
                     VLAEGVGSASDLEKELKKESGADLRVTVLGHVQRGGSPTVSDRILASRLGVRAVELLL
                     DGKSARVVGIKENKIIDLEISEALAQKKVFDKEAYEMAKILSI"
     gene            complement(20634..24203)
                     /locus_tag="KR294_001025"
     CDS             complement(20634..24203)
                     /locus_tag="KR294_001025"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HBH0239129.1"
                     /translation="MNKDFAHLHVHTEYSLLDGFSRVKKLIKRAKELNMSSIAITDHG
                     CMFGVIDFYKTAIKEGIKPIIGCEVYTAARGLRDKDPNYDKYQGHLVLLAKNMEGYKN
                     LIKIVSTSYVEGFYYKPRVDMEELKKHNKGIIALSACLAGDVARALMNRNYEKAKQFA
                     LDYRDIFGEENFFLEIQDHNLPEQKEVNSGLVKLSKETGIPLVATNDVHYVNKEDSKI
                     HDVLMCIQMGKTLNDPNRMRFGSDEFYLKSREEMEELFPYALEAIDNTVKIADMCNVE
                     FDFNTIHLPKYDVPEGYTPETYLRELCFNGLKERYDNPSNEILERLNYELDVIEKMGY
                     VEYFLIVWDFINFSKENNIIVGPGRGSAAGSIVAYTLKITDIDPIKYSLLFERFLNPE
                     RISMPDIDIDFCYERREEVIDYVKRKYGDDHVAQIITFGTMGAKAAIRDVGRVLDIGY
                     NKVDKVAKEIPFALGMTIDKALDTNPNLKELYDQDPETKEIINISKQIEGMLRHASTH
                     AAGVVISKNPVDEYVPLYKHQDAITTQFTMTTLEELGLLKMDFLGLRTLTVIRDTLDL
                     IEKNRVIKNYTEKIDFSKMDYDDPKVYEMLSSGNTLGVFQLESAGMRSFMKQLKPDNF
                     EDIVAGISLFRPGPMDSIPAYIKNKSNPKDVTYLHEKLKPIMEVTYGCLVYQEQVMQV
                     VRDLGGYSYGRSDLVRRAMSKKKMDVMEEERQYFIHGKFDEDGNIEIAGCIRNGVEEE
                     IANKIFDDMIDFARYAFNKSHAAAYGVLAYETAYLKTYYPVEFMAALITSVMGNTDKV
                     VEYIRECKALEIDVLPPDINKSFSKFSVEGDNIRFGLAAVKNVGVNIINNIIAERESN
                     GLFVDLVDLVKRLDQKDTNKRVIESLIKCGAFDNISENRASLMAGYESLLESVSMDRK
                     KNVQGQISLFDAFGDSEEDSDFQQIYSLPKRQEYEERERLNLEKEVLGMYVSGHPLSQ
                     FEKELQEKTSMDNGKLNSLKEEEESYLQMNETDVIMGGMIVTKTIKTTKRNEIMAFIE
                     LEDLYGAIEIIVFPQLLQKYNVILNEDNIIYVKGTLSIKEGENAKLIAREIKDINDDT
                     DFADRNYNSGRTRNVENIKPESGKKLYLKIDSMSDTDTTNNIVEIAKQYPGNDSIYLY
                     PMDENINGKRKAYKMTGALTCICDEFINNLEELLPKDNIKVKA"
     gene            complement(24360..25307)
                     /gene="whiA"
                     /locus_tag="KR294_001026"
     CDS             complement(24360..25307)
                     /gene="whiA"
                     /locus_tag="KR294_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HBH0239130.1"
                     /translation="MSFSTETKNELARVISGNECCNIAELSALVKSGGSIQIVGYKKL
                     NLKITTELNSIARKVFKLLKKNFNINTTISVNKNQMLKRNNSYVLMVTSEMGSEMLLK
                     KLGILEDKEGFFTINKISENLIKHEGCKRAFIRGAFLGGGSISDPEKNYHMEFVTNNE
                     EFADSLKELINSLGFNSKIVARKNNHVVYIKESEQISDLLSIIGGHHALLSLQNTKIV
                     KEMRNNVNRIVNCETANLSKTVNAAVRQVENIKLIQETIGISSLPENLQEIAKIRIEY
                     EDMTLKELGEMLEPPIGKSGVNHRLRKIEEIATDLKKKS"
     gene            complement(25324..25749)
                     /locus_tag="KR294_001027"
     CDS             complement(25324..25749)
                     /locus_tag="KR294_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBH0239131.1"
                     /translation="MREEVSAGGVVLFGNTILLLRKFNGDWVLPKGKVEEGENNQEAA
                     LREVSEETGVKADILKYLGEIHYTFKENWDENRAVHKTVFWYLMQAKNMDTIPQKEEG
                     FIDAKFIHLDRVVDLARYDDEKEIIKVALQEIKKRLKKN"
     gene            complement(25818..26924)
                     /locus_tag="KR294_001028"
     CDS             complement(25818..26924)
                     /locus_tag="KR294_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HBH0239132.1"
                     /translation="MAKLLIIVGILGWIALIVSLFIYKKAKNEKVKLFQRSIVENREP
                     NVVVIGGGTGQSVFLRGLKHTTQNITAIVTVADDGGGSGVLREDLGMLPPGDIRNCLL
                     ALANIEPTMNEVMQYRFTEGLLKGQSFGNLFLAAMNGLYGNFEKAVYKLSEIFAITGR
                     VLPVTLEDVNLVAKLENGNIINGESSIPEESKIQKSSIDKIFLNPKDVKPLKDVIASI
                     YDADIIIMGPGSLYTSIIPNLLVEGIVDAIKSSVAPKVYIANIMTQPGETEGYNVLEH
                     VNAIVKHTDENLIDYVIANNEILPEEMLDLYKQDGAEQVLLDKKQKDKLKEMGIKTVE
                     KNLIEIKNNYIRHDAKYISNIVIELALNHNYNKS"
     gene            complement(26936..27793)
                     /gene="rapZ"
                     /locus_tag="KR294_001029"
     CDS             complement(26936..27793)
                     /gene="rapZ"
                     /locus_tag="KR294_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HBH0239133.1"
                     /translation="MKFVIVTGLSGSGKSETMRALEDMGFYCVDNLPPALITKFAELC
                     YQPNSSIDKVALGIDIRGRKFFEALHESLNYLEKENYEYEMVYLDCNDDVLLKRYKMT
                     RRNHPLAKDMQIPEGIKMERKIMEPLKELSTCIIDTTNMKPKDLKEEIKKIYSSGEDN
                     PNLTISVVSFGFKHGILADADLVFDVRFLPNPYYVEELRAKTGDDKEVRDYVMNSKIS
                     EEFYVKLLDMIHFLVPQYIEEGKQHLVIGVGCTGGRHRSVTITNLIAEDLSNKGYRVV
                     KKHRDSMLR"
     gene            complement(27824..28537)
                     /locus_tag="KR294_001030"
     CDS             complement(27824..28537)
                     /locus_tag="KR294_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HBH0239134.1"
                     /translation="MKILADYHTHTLYSHGKGTIEDNVKVAISKGIKTIGISDHSYKH
                     IAYGVKKKDILKMREEVDYLNDKYTDINILLGMECNILDDKGNIDMDDKFIRDFDYIM
                     AGYHFGSTPTSLRSLLNHCNNYIFKTEKAKEYNTKAVINAISNNDIFIITHPGDKGDV
                     YIEEVAKTAKKTNTRLEINSSHSFLNVNQLNKIKGLENKFIIGSDAHCPERVGDFELA
                     MKTISDSNLDISLVENIII"
     gene            complement(28541..29455)
                     /gene="murB"
                     /locus_tag="KR294_001031"
     CDS             complement(28541..29455)
                     /gene="murB"
                     /locus_tag="KR294_001031"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HBH0239135.1"
                     /translation="MNNQDIYINLLNILSKEDIKVDEPMKKHISFRVGGPADILVRPR
                     TEEQLKNVLKLVKEESIPYLIIGNGSNILIKDGGIRGVVIELADNFNSYEINDTRMTA
                     QSGALLSVLGKALQKQELKGFEFASGIPGTLGGALAMNAGAYGGEMKDIVKSVRLMDM
                     EGNIFELSNEQMEFGYRKSIISKNGYIALSAELELQEGNYDEIKSLMDDLATRRITKQ
                     PLNFASAGSTFKRPTGYFAGKLIEETGLRGLTLRGAQVSEKHCGFVVNQGEASAKDIL
                     DLIYVIKSAVYAKFGVMLEEEVKILGED"
     gene            complement(29728..30498)
                     /locus_tag="KR294_001032"
     CDS             complement(29728..30498)
                     /locus_tag="KR294_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HBH0239136.1"
                     /translation="MSKGFLTPGETAQATISAGIKKANISTQNAILLGLFGGAFIGFG
                     ALGSMIVSQTFGKIDPGVASFLSAMVFPVGLMLVVVAGAELFTGNTLMAIALMDKKIT
                     LGKMLRNWGLVYFANLVGSILLVALVFYSSTLTGDAATKAIAVAEAKVNSTIASMFLK
                     AILCNILVVLAVWMATASQDIMSKLASCWTVIMLFVLCGFQHSVANMFFIPMGMALGA
                     NITMVQFITNLVFVTLGNIVGGSIVVGGIYYLCYVKNS"
     gene            30816..32297
                     /gene="cls"
                     /locus_tag="KR294_001033"
     CDS             30816..32297
                     /gene="cls"
                     /locus_tag="KR294_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HBH0239137.1"
                     /translation="MFDISFFEMSIYEIAVTTIYIINFMVILNLIFREKRNINTTLTW
                     LLILVLIPALGFILYIAFGRNISKNNMFRLKEKDDKIIKSNILDTQVKLQSTSEIDSD
                     IHQHKDMIYALANSNNAHYTNNNDVWIYAESSQFFNSLLEELKKAKKYINIQFYIFKD
                     DKIGTEIIDILIDKAKEGVEVRLLFDAVGGRTLKNSTLSRLKESGVKVGSFFPSFLKI
                     VNFNLNYRNHRKIVVIDGKVGFVGGYNVGDEYLGRNPKFGLWRDTHTKLTGDCVIDLN
                     MRFILDWRYTTKEDLDLEKYFIEEDTNSNHPSENIGIQIVSSGPDISELDEIKYGYLK
                     MIQKARKYIYIQSPYLILDSTFIDTLKIACLSGVDVRVMIPSKPDHPFVYWASYSYAG
                     ELLKFGAKIYTYGQNAFLHAKTIVIDDSICSIGTANMDIRSFELNFEVNAFMYSSKKA
                     LEQRIIFENDILNSKEITLDIYNSRSTYIKIKESISRLLSAVL"
     gene            32615..33112
                     /locus_tag="KR294_001034"
     CDS             32615..33112
                     /locus_tag="KR294_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase subunit E"
                     /protein_id="HBH0239138.1"
                     /translation="MCDFISHNKQLFDELDIFIDSLATKEGALIQVLHEAQGIFGYLP
                     KEVQLHVARKLGVAPAKVYGVVTFYSYFTTEPVGKYKISVCLGTVCFVKGADKILSAF
                     EKQLGIKVGETTSDFKFSLEGLRCLGACGLAPVVTVNGKVYGKVKPDQVSEILDTYRE
                     LELNC"
     gene            33129..35015
                     /locus_tag="KR294_001035"
     CDS             33129..35015
                     /locus_tag="KR294_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoF"
                     /protein_id="HBH0239139.1"
                     /translation="MRKVNSFDELKVLADELKPNLSLRKNYSKENVLRRELLVCCDTG
                     CTSSNSLEIVSELENEIKKSGIQDKVSVRLTGCFGFCAQGPIVKVYPDNVFYVKVEPS
                     DAEKIVQSHLIRNTVVEELLYEEESLSKKVEEQEEMSFYKKQLRIALKNCGLIDPDSI
                     EEYIANDGYLALGKCLTSLTPQEVIAEVKTSGLRGRGGAGFPTGSKWEAASKNPAGPT
                     DKKFVVCNADEGDPGAFMDRSVLEGDPHSVLEAMAICGYAIGSDTGYIYIRAEYPKSI
                     ERLKVAIAQAEKYGLLGENILGTGFNFKLELKYGAGAFVCGEGTALMHSIEGRRGEPR
                     MKTYSSSKSGLWKSPTCLNNVETFANIPAIILKGGDWFANLGTEDSSGTKVFALGGKV
                     ENVGLVEVPMGTTLRDIVFEIGGGIPEGKKFKAVQTGGPSGGCIPTEHLDTPIDFGSL
                     SSIGSMMGSGGMLVLDESDCMVDIAKFFLEFTVEESCGKCTPCRIGTTRLLEILTKIT
                     EGNGTLQDLDDLENLAETIQTASLCGLGKAAPNPVLSTLQYFKDEYIAHVVDKKCPAG
                     KCQNLLSYFITDDCKGCTKCSRVCPAGCITGSVKEQHTIDTSKCLKCGACIDNCTFNA
                     IIKK"
     gene            35038..36819
                     /locus_tag="KR294_001036"
     CDS             35038..36819
                     /locus_tag="KR294_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron hydrogenase small subunit"
                     /protein_id="HBH0239140.1"
                     /translation="MSLVNLTINGKHVSAPSGTSILDAAKLINIKIHNLCHLHMNEID
                     KLDTCASCRVCMVETERGLVPACGTVIKEGMKVQTNSAKALNARRTIVELLLSDHPQD
                     CFVCEKNGDCELQTIAADLGVRKIRYQGSKSFAGKDTSTKSLVKDHSKCILCRRCETV
                     CNDIQTVGALSGVNRGFNTLVSTFFNSDMVETECTFCGQCISVCPTGALTEVDNVPKL
                     WDVLNKKEKTIVVQVAPAVRVAIGEEFGLEPGSISTGKMVAALKALGFEHVFDTNFGA
                     DFTIMEEATEFIERIQKGENLPILTSCCPAWVNFLEHNYPDKLNLASSCKSPQGMFGS
                     IAKNYYAPKILGINPEELYVVSVMPCVAKKYEASREELSESGILDVDLSITTRELAKM
                     IKEAAIDLPNLQDQDFDNPLGKSTGAASIFGASGGVLEAALRTSYEKITNKTLDNVNF
                     TNVRGLKGIREASIDVDGTTVNVCIVNTLKNARKIMDKVRSGECKYHIIEVMACPGGC
                     VGGAGQPYHHGNTEIVDRRANALYEIDRNKAIRKSHENPDLQAIYKDFFGEPNSDVAH
                     KYLHTHYFDKSCVYGECPQECACEEAK"
     gene            complement(36959..38755)
                     /locus_tag="KR294_001037"
     CDS             complement(36959..38755)
                     /locus_tag="KR294_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate oxidoreductase"
                     /protein_id="HBH0239141.1"
                     /translation="MGIEYFSKLLESSTEKELLLSKKSNNISTARLISFLIVIAGFAI
                     GFYNKNIVGIFVGVLSIIIFIALLVIHSKVKEEETYFKSKSEVLNKYIKRFGDGWKEF
                     KIDGKEYLKDENSQAKDLDLFGRASLYQYICVANTSYGKNFLAKYLWNENPDENVILE
                     RQRAIKELLSKDDFSIHIQTLSNIIGKEQKNNSDSSIESFIEYGENKNVYIPKWMHIF
                     TWGLPTATILSFIFCMLGFLPVLPVFLLFIIQLGFSGFGYPRLMQTLAPLFSFSRSIQ
                     VYEKMFEVLEKETFESAYLKELQDKLSKGSGVSRGVKQLNSIGNAVNLRYNQILYIIA
                     CGVLMWNYHCAEALERWKGIYGNQIRDWFESIGEFEALISLTVVSHVKENTCFPVIKY
                     EDTPRLKVEEVYHPLIAEKSVIANSIQLNSQTCIITGSNMSGKTTFLRSIGVNLVLAY
                     AGAPVCAKSFDATCMAIFTSMRIQDDVSQGISTFYAEILRIKSMIQYSLKELPMLVLV
                     DEIFKGTNSADRIIGASEAVKKLSKPWVISMVTTHDFELCDLSGSGDVEVVNYHFSEY
                     YVDDKIHFDYKIKDGRCKTTNAKQLMRMAGIL"
     gene            complement(38969..39898)
                     /locus_tag="KR294_001038"
     CDS             complement(38969..39898)
                     /locus_tag="KR294_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HBH0239142.1"
                     /translation="METSNKVSIREIIKELKLKVVYMPDDVDYYVYSQDINRPGLQFA
                     GYFDYFAYERIQIVGKTEYNFFGLMDSHIREEVLDRFFSYEIPALIISRDLEIKPDVI
                     EKAKKYKRILLSTNRNTTRLINRLSNYLDNKLAPHTTIHGVLVDIYGIGVLIKGESSI
                     GKSETALELIQRGNRLVADDAVEIRKLDESMLVGQSPELIRHFLEIRGIGIIDVRSLY
                     GVGAIKNSKMIDLVVHLEAWDETKYYDRLGLDKEYEEILGVNVEKLVVPVKPGRNTAM
                     ILEVAAMNFRQRGMGYDAAQEFTKKLSKLIDTK"
     gene            complement(39898..41715)
                     /gene="uvrC"
                     /locus_tag="KR294_001039"
     CDS             complement(39898..41715)
                     /gene="uvrC"
                     /locus_tag="KR294_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HBH0239143.1"
                     /translation="MFDIQEHLKKLPSEPGVYLMKDKYDHIIYVGKAISLKNRVRQYF
                     QSSKNHTSKVKSMVKNIYKFEYIITDSELEALILECNLIKRYRPKYNVVLRDDKTYPY
                     IKVTTNEDYPRILKVRRVLKDKAKYFGPYTNITAVNDTLELISSTYPIRSCKIDIDKA
                     IKNKTRPCLNLHINKCLGPCTGNVSKEEYGKMIEEIIMCLSGKEEKLMELLKEKMNES
                     SMNFRFEEAAVYRDKIKSLEEMIQKQKIDATVSDLNQDVVAMARAHNEACVQVFFIRN
                     GKIVGREHFILEGVMDSPRASILSSFVKQFYNEQEYIPKELIIEDEIEDSSILEEWLS
                     SKKGQKVTIRVPQKGEKKSLVEMVRKNAVEYLEKFSDMNKRKYEKSIGALEELKQILN
                     LEKLPIRIEAYDISNIQGVDSIGSMVVYTNAKKDKKEYRRYKIKTVIGPNDYDSMAEI
                     VDRRLKHGNLPDLILLDGGKGQVSAVKKVLELNDVDIPLWGMYKDDKHRTKGLICKEK
                     EIELDKTTNLYRFIASIQEEVHNYAITYHRSLRNKALTKSILDDIQGIGEKRKKSLLN
                     HFKDVDAIKKATMEELLEVDGMNKSIADNVYNFFRKEEN"
     gene            complement(41974..44799)
                     /gene="uvrA"
                     /locus_tag="KR294_001040"
     CDS             complement(41974..44799)
                     /gene="uvrA"
                     /locus_tag="KR294_001040"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HBH0239144.1"
                     /translation="MEDKIIIRGAKEHNLKNIDLELPRDKFIVFTGLSGSGKSSLAFD
                     TIYAEGQRRYVESLSAYARQFLGQMEKPNVEYIEGLSPAISIDQKTTSKNPRSTVGTV
                     TEIYDYLRLLFARVGDVYCPTCGEKISQMTIQEIVDKMLDFPDRTKLQILSPIVRGQK
                     GTHKKVFDNIKKEGFVRVRVNGENYEVSDDIILNKNQKHNIEVVVDRIVIKDGIESRL
                     ADSIETAVKLSDGLVIAQIIDGEEILFSTKFACPEHGIGIEELSPRMFSFNAPFGACD
                     VCNGLGESKEVDPELVVPNKDLSIKQGAVAAWGSTGVNDDTYYSKMIKSLAEHFNVSL
                     TTPFKDLPDDFVEELLYGKDNIIVEFTYESKFGGTRNYKSYFEGVIVNLERRYRETNS
                     DYMRDKIEEYMAERPCPKCKGMRLKKEVLSVLVDGKNIMEVTNLSVNELIDFMENINL
                     TEKQRFIAHEIIKEIKGRAMFLRDVGLDYLNLSRKAGTLSGGEAQRIRLATQIGSALV
                     GVLYVLDEPSIGLHQRDNDRLITTLRHLTDLGNTLIVVEHDEDTMREADYVIDIGPGA
                     GIHGGEIVAQGTLDEIIENENSITGQYLSGKKQILLPETTREGNGSFIEIVKASENNL
                     KNIDVKFPLGKFTCITGVSGSGKSTLINDILYKGVASKVNRLKQRAGKHKEIKGIESI
                     DKVINIDQSPIGRTPRSNPATYTGVFDFIRDIFASTNEAKARGYKKGRFSFNVKGGRC
                     EACKGDGIIKIEMHFLPDVYVPCEICKGERYNRETLQVKYKDKTISDILDMNVEEAVE
                     FFENIPNIKRKLETLMDVGLSYIKLGQPSTQLSGGEAQRIKLAAELSKRPTGKTLYIL
                     DEPTTGLHMADVDKLIQVLQRLADTGNTIIVIEHNLDVIKTCDYVIDLGPEGGDKGGT
                     IVATGTPKEVSKVDGSYTGQFLKKYFS"
     gene            complement(44818..46788)
                     /gene="uvrB"
                     /locus_tag="KR294_001041"
     CDS             complement(44818..46788)
                     /gene="uvrB"
                     /locus_tag="KR294_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HBH0239145.1"
                     /translation="MDFKIKSDFKPTGDQPEAIKSIVDSINRNEKFSTLLGVTGSGKT
                     FTMANIIQQVKKPTLIMAHNKTLAAQLYSEFKEFFPDNAVEYFVSYYDYYQPEAYVAH
                     SDTYIEKDASINDEIDKLRHSATASILERRDTIIISSVSCIYGLGDPKDYKELMLSIR
                     PGMQRDRDDVIKRLIEIQYERNDINFTRGTFRVRGDILEIFPASNDEKAIRIEFFGDE
                     VDRITEIDYVTGKIVGTRNHVVIFPASHYVTTPERIEKAIVEIENELQEQIKFFKEND
                     RLLEAQRIEQRTKYDIEMLKEIGFCQGIENYSRHITGRSEGERPYTLMDFFPDDYLII
                     VDEAHVTIPQVRGMYAGDRSRKTSLIENGFRLPSALDNRPLNFQEFEGNINQMLFVSA
                     TPGPYEIQHSETIAEQIIRPTGLLDPIVEVRPINNQIDDLVGEITKTIEKNERVLITT
                     LTKKMSEDLTNYLKEIGIKVKYLHSDIVTLERTEIIRDLRLGKFDVLVGINLLREGLD
                     IPEVSLIAILDADKEGFLRSETALIQTIGRAARNENGRVIMYADRITDSMQNAIDETK
                     RRRDIQNLYNEEHNIIPKTIQKNIRDSIEATKVAEEEVVYGISDTDDKDEIRANIDKL
                     KSEMMEAAQNLQFERAAELRDKVKQLEEKLEK"
     gene            complement(46975..48237)
                     /locus_tag="KR294_001042"
     CDS             complement(46975..48237)
                     /locus_tag="KR294_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase family protein"
                     /protein_id="HBH0239146.1"
                     /translation="MTKVIVLSVDSLFEKDLEFVKNLPNFKSILENCSIVKNINCVYP
                     TLTYPCHTSMVTGVYPKKHGIYHNEKFDPNKENKDWYWYSKDIKAKTIIDVAKENNLT
                     TSSVLWPVMGANPNIDYNIAEIWAPSREDDPRETFERSSSKVIMDGIYNRHCHYIDWK
                     LEPNMDLFGVNCSVDIIKEYKPDLMLIHLATLDHTRHNYGLFNDEVDKALKMNDKWLG
                     DIIQATKDAGTYKDTNFIILGDHGHLRVDKVINPNVLLKSNGFIKVENGEVKDFDAYV
                     NSSGISAQIIVNNLDRLTELRELLEEFKEELFIENIFTKEEASNLGLEGDFEMVIEGL
                     EGISFGNDFEGSIIKDSDIKDYKFAVATHGHLPTKGNRPPFIAFGPNIKGGVVIEEGD
                     LRAHAATILKMFNLKLDGVEKEAFDFIM"
     gene            complement(48300..49604)
                     /locus_tag="KR294_001043"
     CDS             complement(48300..49604)
                     /locus_tag="KR294_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBH0239147.1"
                     /translation="MKLKRKLATGLAITLLLGSLVGCSNSNDANASKGEKTDSNITKI
                     DFWAPLGGTNGETAQKMVDQFNSEHKDVQVNMLKQKDYYENATKLQAALTSKDQPDVT
                     LLEITQTGTFASAGALVDMSKYFDKTYQERFFSGLLTNSYYEDKFVGMPFNRSTPILY
                     INKDMATKAGLDPSGPKSWEELKDYASKMTNKSEDTYGFETPIDIWFYEAMVMQSGGE
                     ITNGKKVAFNNEAGQAPVKFWQDMMKAGIMKMPPGEDYNAWDVAKQDFVNGKVGMIFT
                     STADLAGLMQQTEGKFEISTAFLPKNQKYATPTGGANLVMLEGGTDKEKEASAEFIEW
                     MTQTDKIVQFSSSTGYLPTTEDATNSEKLQTLYKEKPQYKVATDQLQYAVALPMLNGY
                     KEATDKLMDEIKKGLTDLNANPKDVVSKGTSAMQAVIDKTNK"
     gene            complement(49635..50495)
                     /locus_tag="KR294_001044"
     CDS             complement(49635..50495)
                     /locus_tag="KR294_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBH0239148.1"
                     /translation="MDIIQPIKKDKVDIKKIASKSIEILILLLLSAIFIFPFIWMLST
                     SFKNPQEMMQLPPTIIPNDIVLENYSTAWHSGPFFRYLLNSVFVTGSVLIVQFLVMVP
                     AAYAFSKIKFKGEKMLFGLLLVGLMIPPQVTFLPVYMMMSKFGFINTYVPLIIPFMTS
                     SFGIFLLRQNFMQISDEIIEAAKLDNASDLKIMFRIMVPMAKPAVITFILFNFIYHWN
                     NYFWPLVMTNTDAIRTLPIGVALLKSSEGITAWNVIMAGNIILILPIILVYIFANKKV
                     KEAFMYSGIK"
     gene            complement(50539..51408)
                     /locus_tag="KR294_001045"
     CDS             complement(50539..51408)
                     /locus_tag="KR294_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBH0239149.1"
                     /translation="MKKQFNKAYLYITPAIIGTLLFIVYPIIKTISLSFKSGSLLSST
                     FENVGLNNYTELLKNPEFIQTITNTAIYTFFMVTISISLAIVLAVWLNKNSIIHNLTQ
                     SIIFTPHVISLVSVAVLWLWIMEPQYGFLNWILSTLHLPTSKWLSSESSALMSLILIG
                     IWKTLGYNILIVLSGLKSIPNYIYEASKLDNANKITNFFKVTLPLLSPTIFFLMITTT
                     TASFQVFDEISIMTQGGPVGSTNMLSYYIYESGFIYYDIGQASAASMFLLAIVMIATY
                     ANFRLLSKKVHYQ"
     gene            complement(51392..52462)
                     /locus_tag="KR294_001046"
     CDS             complement(51392..52462)
                     /locus_tag="KR294_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0239150.1"
                     /translation="MADIRLENVTKSYNKKNTVIENLNLTIEDGSFTVLVGPSGCGKS
                     TTLRMIAGLEDITSGRLKIEENDVTKTDASKRDIAMVFQNYALYPHMTVRENIEFGLK
                     NKKVEKEKREKLITEVIDVVGLREYLNVKPGNLSGGQRQRVALARAMVKNPKVFLMDE
                     PLSNLDAKLRNQMRTELIQLHQKLKSTFVYVTHDQVEAMSMADKIVIMNKGKIMQIGS
                     PKKIYQNPKNLFVAQFIGSPCMNILDIKNDIKFGFRPEKATLESINIDGKNDDVFSLF
                     GKVVTKEVLGNETIYCLSVLNREIRVKTENDIFDIGRTLRISVLEKDLYYFDKNGERI
                     EDVKVCKSMYSKIKGDIYEKAI"
BASE COUNT        15508 a        10358 c         7532 g        19507 t
ORIGIN      
        1 gttacatacg aaccagcgtt ataggtggaa tggaaaaata ccaaatcgcc agcctttgcc
       61 tgcgagagtg gaagatgttg ggtagcgtca tactgggctt gtgccgttct cggtaaggag
      121 ataccagctt ttccatagca ccattgcgtc agtcccgaac agtcaaagga agtggttgga
      181 gaagaaccac caaacacata tttccaccct tgatatttca acgcttcatt cattaccttt
      241 tgtgccagct ctcccgatac ctgcggaaca gttaaatact gattgactaa ttccacatag
      301 aacatatttc catagccata ccgccagcct ccgttcttcg caacggctat cgggttggta
      361 taggttactt tctttccacc cgatttctca cgggcgaagc tctctgcaag attaaaagtg
      421 tgtttctttc cgtttcctgc cacatagccc acatagccac cgccatagtt ataggactgt
      481 atcgctacat tcaaatcgtc gatatcttga tttttgcagg aagaaagcag ggacgcaaaa
      541 tacttacacc cctgcttgat tgagctttcc gtatctaagg aactaggcgg taaaccaaga
      601 ctttctgaac tctgcataac atcttctgcc gtaccgccac tttctacttg aatgatagcc
      661 agtagtacat tgacgtactc ggagataccg ttttctctgg cgtatttttc taccatagtc
      721 tgatgtttca aaacttctgc ggataagttc atacccgtaa tgccagaaga aaagttgctg
      781 ttttcgtcgt cgctgtccgc actaatcagc accccaaaga aaagcaccag agaaaagaga
      841 ataggaaaca gacttccaat gatagcgata tgtttcagtt tcattttttc ttctgtcctt
      901 tcttcgttac aagattacgg attttctctg tggtctgctg gttcttctgg acagtctggg
      961 tctgctgaac ctttgtccta cggtctttgg tgtaattctg gcgtgtttcc tttgacacgg
     1021 taactttttc tacattctgc ctatatgtcg attgggtcgc tttcccgtca ggagtactag
     1081 aagatagcgg acgttctttg acaccgcttg tcttaactgg ttcgcttgct ttcgtagtcg
     1141 gagttgtggc agggcgtttg acttcctgca ttttttccgc acccgtcttt gaaacggttg
     1201 aagctgtggc tggtcgctca tggggacggg tagctcccgt tgtcgctgat ccgtcagcct
     1261 ttcgctgtgc ctgccttgct tcttgtgcct tttgaagctc catacgcttg acagcgatac
     1321 ttttcttatg ctgttcctgc ttttccaagc gtcccgtctg tctggactgc tgttcctgca
     1381 ccataccacg cttgaaatca gacacgctgg actttgcctt ttcctttgcg gaatacaccg
     1441 cataagcggt ctgtgtgggc atatccttga tattctcttt gacagcgttt gccttgtctt
     1501 tcactttatt tttcgtatct aagacagcac ccacctttga gcctgcacgc tgtcccatac
     1561 tggaagtggt attgccccga ttttctttag aagccgtatt ttttctttcg gctctcttgc
     1621 cagcaacggc acttccagct accgcaccag ccacaccgcc cgaaataccg ccagcactta
     1681 cagcccttgc aatacggtgt tccatacgcc tagcccgatg tcgcatgaac agatacggtc
     1741 tgcggaatat cctgcgtccc atgctttgac tgtcgccagc gttgagagaa aacatactca
     1801 ttaagtcgcc cagcttcata tagataccag cgaaacatac tatctgcaag aacgccacca
     1861 tgaaaaacgg atagtccgtg gatatgttat aaaacatact ggaaatgcta aacgcaaccg
     1921 ttacaatgag cgttattcct gcccgtgtca ttatggtatt aaataccctc acgattgcct
     1981 gctttgccat gctttcatag ctcggtatca tggaaagtag aaagctgata ggtaaaaaca
     2041 tagcgaagat aataaaaagt atctggctga acaacatcat acccgtaagc aagaatacaa
     2101 atatcgtaat accaagatta aagaacaaga ggaagaacac catacctaaa cggtttacca
     2161 cctgcggtat cgtcagattg ttgttgtcgt tgtcctcgat ttctgttttc acgacttctt
     2221 ctctggtctt tccgtcctcg tcctctggac ttgccgatac gagagcttcg acacggtctg
     2281 tcccgatttc ctctgcgttg ctgtttccaa actgtaagag tagccacggc tgttgtactt
     2341 gaatagaaaa taggctgtcc cgtatcaagt ctacgctgtc cttgccctcg ctgtcagagt
     2401 tggggagcat gatttttgtt cccaaatcaa gcgaagcggt actgatgtct gatgaaaatt
     2461 catttatctt cttgatgtag tcgggagcgt aggcaataaa cgaagcggac agcacgaaca
     2521 ccaccacaaa gttgataaca gcgtgaagtg ccttgctggt ttcccgtttt atcagtcccg
     2581 tataggcaac atacattccc accactaaga taataagaag caggaaacca acatagaagc
     2641 ccgtagaaga aaagccgttc tcggtaacgc ctgcaagggt ctgtatgctt tttccgatac
     2701 tgtctgccat atcgttaata aaatcaagtt tataggcttc ctgcaccaca tagccagttg
     2761 cattgcttaa ataaaggctt atcgtccaga caaagttggt aatgcagtaa agcccgtact
     2821 gtaccgattt tccgataccg tccagccagt tccacggaag ccacgaccag ctattatcga
     2881 cgaaaaaatc aagctggtag ttggaaagcg gatattttga atatagattt tctgcgttta
     2941 tggtatcgtc cacaagcccc gtcgcatgag ccaccgtccc cagaagtgaa agcaggataa
     3001 gggaaagtgc caccacgaac agagccattt tgagaaagtg aagtatcttc ctttttgtga
     3061 acgcactctg tatcctttct ttcatcactc cacctcattt ctctgtacgg gcggtctagt
     3121 atcaaaggcg tgtagtaatt cttcaaagac tgggtgtatc tgcaccacac cgacacgccc
     3181 gtataagtcc tgcaataaac attgtccgtt ctccaaatca cgcaagcgtt tctggttgtt
     3241 ttcgtcgtcc ttgtcgatac cgaaaaattc taaggtctgc tttatctcgt tgatgtcagt
     3301 agaacgaaat gcaaacttca aaccgatatt gtttttcaga ctttcctttg acacgtcata
     3361 ggcagactgg gtaacgaaat aaacgcctgc ctgcatagct cgtccagcac gaaccagctt
     3421 atttgatagg gtttcgcctt gtgccacatt taagaacgcc cacgcttcgt ccaaatctac
     3481 aatcttaaaa atgcttctgt ccgaatggat aaaatcaagg gcaaaggtac taatcacaat
     3541 cagcatagac accgacaata attcaatggt cgtgtattcc tcaaaagtgg tatctttatc
     3601 tggcagtaca aggtctgcta cttgaatgat attgagctgg ttatcaaggc ttatagcatt
     3661 ttctaccgtc ccgtctgaaa acagcaggtg tgcaaagtcg tagtccgtga agctgtcgat
     3721 atggtctgcg atattgcgtg agatagcggt atcttctttt ctcaattcct caataacgtg
     3781 taacagtcct ctattttcac tctgggtaac agaacgcacc gcttttcgta acacggggaa
     3841 tttttcgccg tccctagagg aaatacccgt aaggaatgtt aagatgtcga ttgccagact
     3901 ttcagcgtct ttcacattct tcataatcac aaatgggtca agaagtcctg cattgtcctt
     3961 gtcgctggta aggtttacga tattgatttc atgggctatc tctgggagcg tttctttcca
     4021 gttgccacgc tcacttttag ggtctaacag aagtgcttga ccgccaaaca gcaccgcata
     4081 atatacaagt agattgttgc agaatgactt tccaccgcca agacttccca caaaagcaga
     4141 agcaagggca ttagtaactg tgccttttac tccctgcgaa gctaaagacg gttgcaggta
     4201 cacatttctt cccgtatcaa cggaatagcc catatagata cccgtgtttt cccctaactg
     4261 ctgggtcgca ccaaaaccaa gcccagccaa gaagtctgac tttacatact gcacatagtc
     4321 attgatatat cgcttgctgg caggtaaaaa ttcagaatga agtcccaaca tatcgccagc
     4381 aggacgcacc agttttacat tgaggtcgtc gtaaaagtcc ttgacttcat cacaacggcg
     4441 tttcagctcg tcaagatcgg gtgcagacac ccgtatgacg tagcttaact tatacatact
     4501 ttctttgctc tggtctaaat cggtttccag ctcgtccacg ctgtctaaag cgtccaccac
     4561 atttgagctg gtttcacttc ctgcttgata ggcgtgatta tccaaatctt tcaattcctt
     4621 tttcttgttg cggactgtcg ttaatgcctt acggttctcc acgatttcta cattcataga
     4681 agtatcaacg gggaatgtga attgctgttg ctggaaatag aagatttcag aggacggaaa
     4741 atccaactcc ccgacaatta cattgacggt aaaataggac acatagcttt ccttgtcctc
     4801 atgttccaat cgtaaatacc gctggctttc ctcaatcaca caccttgtcg gacggataag
     4861 gtcgtagtat tttatcagcg tttctttctt caatttcttc tttggtagct ggtactcata
     4921 atcttcatag gcgataccgt ccctgccgta aagatgttcc atgagatacc caaaatcatg
     4981 gatttccaag cgacgcacct taaagcgacg ggagatttta ttttccagta acttttccat
     5041 tttcatgtaa cggttgattt catcattcgg catggaaaca aaatcattca tcagcgtgtg
     5101 gttcacttca tgaagaaatt ccttgaacgt cagccatgcc gattttttga tgttcttcag
     5161 attgagctgt tcttccgtaa ccatgagctt aaagccaaga aaaaagcggt agtccacttg
     5221 attgtcccca atcattgata ctaacgcttc ggtctgttcg tctatttttt ggactgccac
     5281 ctcacgaagt ttgcctgtta ccagtttctt tgactgctcc tgcatacttc taatggagct
     5341 ttctgtggca atctgcaacg catgaatttt tccctcacgg gactgtgcga ttagctgtcg
     5401 aaaactgtca tgcacgataa atttctgctc tgcggataga aaagaatagt tgtacggtat
     5461 catctcatag taggcgaaca cctcattgtc cttgttccag acaaggttat tgtcaatata
     5521 ttttatcggg aacatagttc acactcctta ctgccgtgat tgtttcattc aatatctgct
     5581 tatgcagttt tacggctttt cctgcataag tgattttagg tcgcaaggca taggttatct
     5641 gtgatttcaa aaagctgtac ggcttctttc cgtcaaaggt tttctgcgac ataaaccaag
     5701 tgagagcaac gggaataccg aagtatttga gaaatgctcc ctcaatcatg gaaagtgggg
     5761 gcatatcccc aaacagaatg atgataaatt ccgtaatcac aaaccatgta atctgtgtaa
     5821 aggtaacggg aaagggtaag ttaaagtcat tgattgcata taagactttt tccacgttcc
     5881 agatacccgt gtagctttta atctttttca agttctttca gcccctttcg taagttcttc
     5941 aaagagaaaa ggacagccat tttcagactg tcccttaaag agaaatacgc tgtcagtagc
     6001 aacaatgctt gttgctgatc ttccagcgtt aatatggtat ctcacagata cctcggcttg
     6061 tttcaatgaa tcgaccaccc atatccaaat ctcgcccgta ggcttcatag tcaatatagt
     6121 tctgtaagtt agctggaatg tccccaagtg cgttcaattc gtctatgtag tagtaggcaa
     6181 catctgtcat ggtttcacaa tcgggataaa aataaatatc gtccttatgt tccacgactt
     6241 cttccagcgt cccatagtgg ctgataaatt cgtccagaca ctctacgata tagtcgggaa
     6301 gttcctctat catttcatac atttcattga gttcttcaat ggaaacatat tcccctatgt
     6361 cgataggaaa gttgtcggta tcatggacag cgtattcttc gtactgttca ttcaagccga
     6421 ttttttcttt tacatcttcc tcgtcaatag ggaaagtgaa ccacgcaccg actaaatatc
     6481 cctcattgta tctgccaaga ttagcaatat aaaccgccat atcatcaatc ataagcacca
     6541 cctcatttcc tattctggca gttcaaagat actgttttcc gttacaagat agcgtttgtt
     6601 ttcaagtaag tgagaagcgt aggcttcaaa atcgaaatag tatgcttgac agtcctcgga
     6661 taaatgtttg aatgtcgggt cgttcatcag cttttgcctt gcaacatcta tcatgctttt
     6721 acagtcgtga taaacggtaa tcacgttcct gcaaatataa agtgcttcta agttctcaaa
     6781 cacggtaaga agttctacat attcttcctg catatcggct gatagctggc ggtacataaa
     6841 atctaattcg ttaagctggt acacgctggt gtgttcgtgg acttcatcag cataaggcaa
     6901 caccttttcg ataatgcggt aatcttgact ttctgcaccg acacctaact tttcttcaaa
     6961 ctctgcaaca tctatcggta agtcaaacca gtatgatgtt gtttcttcgc catttgttct
     7021 tcccgtttcc accagtaccc ttgtttcctg cattgttcct cacgtccttt ctgttgtttc
     7081 atcacatctt ttaaggtctg gtatgacata ccaaacacat atttagaaaa atctttcaac
     7141 tgtttttctt catagtcggc agggttcagc cgtttcattt catgccacac cttacgcttg
     7201 taagagggca ggtcggaaat gtattcacag ccgacttttg cctgcatatc tttaaaaata
     7261 tcgttcattt catcactcca atctgaaatt taggtaagaa aaaagcagtc aatcctaaga
     7321 ctaactgctt tgtgtgtaag tatgaatttg tttaagtgta actgatttac catgtgtact
     7381 cgtaaagttt actgtatgtt tgacttttaa ataaatatat acaatcaatc atttgtaact
     7441 tgccgtcttg ttcaaattta cttattatca gattatcttc atagatatat gctaagaaag
     7501 tatcatactc tgcatagtat ttttctctaa aaagatttga ctctctaaaa tctttttcta
     7561 aagcaattct tatactgtct aaagcatatt taaagttata acaagtatta aaactaaact
     7621 tgtatggaaa aaagaaaaat aagtttttct tgaaagtaag caatttcaca taggtttgta
     7681 tatcaaattc aatcgttcca tactcatatt tctctgtaag acaagaatgt aaactttcac
     7741 aatcataatc ccgcaacgaa gcaaataacc tagttacagt catttgtgta tttggtcttc
     7801 tcggtggaca cttaccaatt acaccatcac agaatttctg tatttgacca gtaagttctt
     7861 ttgaagcatg aagtcttgtt gtgctttcaa gtaatttaaa gtccatttga taattaggtg
     7921 agttacaatc acattctcca tgattttcag atttaggtgg tacatattct gcaaaatttg
     7981 atttttctct aaaatatatt gatttattaa ctaattccaa caagtatttt tcataattac
     8041 aattttcttc atctttaata aaatttttgt ttatgaatac tgcatgtaaa atatccactc
     8101 tcatttcatc tgaaatcata agcactttta ttcctttcaa aaaataattt atcgtaccca
     8161 cattataaca ttctcatatt acagcaacaa taaaattcgt tatgctccaa taatcttatt
     8221 gaacagctct aacagtacat ctttcacacc gccagcgttg aatactaagc cgacagcaat
     8281 aagggcaact accaagaagc caataagttt tgaaaactca cgcttgaacc ctaagtagat
     8341 accgataacc acaatcgcca taagcactaa gctctgtgca tttgataaaa accattgata
     8401 caaattttgt ccgaaattca tttaattgtc ctcgctttct tctaattgtt tcatttcata
     8461 gtcagcttct ttgctgatac tcaaaataca catcaagact acgccgatac ccattcccat
     8521 agataccagc aggaagtctt ttactaattc ccacattttt tatcactcct aactttccac
     8581 caaatctttt gcaggggtcg tctgctgttt gattatcatt tcatgctttt cactcaagat
     8641 tgcctgcttt tcaatcgttt ccatgtagtc tgtaccgttt cccttatcaa tctttttcag
     8701 cattttcaag gtcggtgcta cctgtctttg tacccaacgc aatgtgcggt ctaaggtgta
     8761 aggttctggt tttgtcgtca gtttcagact ttgccgatta tcgccaataa accaagccca
     8821 gcggtcattg agtttccagt catttttccg cttgtctggt tcttcatcaa taaaccgcac
     8881 atactggttg atgatagaaa aagcggtctg ctctgcgtca tagtaggtca gcaaatctcg
     8941 tactgcatag taagcacgtt catttctaag ccgtatctca aaacggttga taatgtcggc
     9001 ttcttccaga ggtgtaccta atttgacata ctgctcatag tccttttcat agatacagaa
     9061 atacacatct gatttcagcg aaccaagata aagggtactc cccatatatt ctctgtcgtc
     9121 ctctctgtgc ttgataagct cgcccgactg gtaatactta tagcttctgg actttccgat
     9181 atattcccgt ttcctgcatt tctccgcaag ctctggaata tccaaaatgc ccgtatggtc
     9241 gttgatagca aggtcgatac gcttcataat gcctccgtct atgagtgcgt ccataagaaa
     9301 gtcataccag cttctttgct gtgccagcag gtaactttca aactgcctgc aaccccgacc
     9361 ctttaactct aaaaggacac ctttttcttc gtcagccgac gtatagataa agatgtcccc
     9421 taatgaataa tgctccgtat aactgtaatg tccgtaatct tcatggagca tataattgat
     9481 attcagtttt aatatgtctt tgatgatgtg ctgtatatcc agcgtgggaa aacgaatttt
     9541 cacataatca aacagcatgg taagcggtgc ttctggattg aaccttgcca gttctttatg
     9601 caaagtttcc agaagttctt ttgacggctt catttttccg ctttctatct tgtttagata
     9661 ttcccttgtg ataccagaag ctaccgccag cctgccttgt gagataccgt aagcaatccg
     9721 cttctcccgt aattctttta tccattgttc ttcattcaga accatacccc caatctgtca
     9781 agtgtgaagt tttttaaggc gacttcacag ccgatttttg ctaggaaacc atgccagaag
     9841 ccttatgttt cctatgtttt tttgtctatt gtctatttgc aaacgtaccc ctctgttaga
     9901 taccgagggg ttttacctgc tggcgtggct tacgccacac cagcaacggc tagtccgagc
     9961 cgtcgccttt cgcttcgcac gtcgccgtcc cgtcctgcct tgcttgtgca agaaaaccga
    10021 ttgtctgcaa aaaatcatgt cctttcggga ctaaaggcgt gtaaaattca cttatgacgc
    10081 ttgttcccac atcacaatag ccacgccctt tgatacgctt ttggaaaaac tgctttttca
    10141 catctgaacc aaacagcata ccgtaaccta actcgctgat acgccccaat cccacacgta
    10201 aattgaagtt atctctgata ccgtccgaga aatattttgc gtctggacgc tggcaggcaa
    10261 cgataaggaa ataacctgct tgtcgtccta acatgacgat tttctttaac tggctaagta
    10321 agcccacact ttcttttgtc cccagcattt caaaaaacgc cacatattca tcaaagataa
    10381 gaaagcaggg tggcagtccc agataggcgt aattttcgcc cgtcttatag ttcgggtgtc
    10441 gtttcatttg ctcgcttcgc tgtaccatgc cctcataaaa agcattgaca cagtctatca
    10501 tttcttcttt ggtgtgatac acgtttccca tgactgttcc caagtctgct aagtccgcat
    10561 ttttcgggtc taagatgtaa aggacagcgt tggtatgcag tagggcttca atgagcgtca
    10621 gaagaaaata tgttttaccg ccaccagtcc caccagcaat cagagcgtga gggagtgcgt
    10681 catattccca gacaagattt ttcatcagtc taagacagcc gttctctgcc cgtacttcat
    10741 caatggtaat gcggttcgct atcatatcat aaagcagggt atattcgata tagccgtcat
    10801 gcagggtctt gtcggtcagc tcacaataca agccactttc caatttatcc tctaaccgta
    10861 aaagctggtc ttgatatttc cccagcgtaa tttcacagcg gatatgaagc agtccctttt
    10921 ccatttgata ataaatcttt ggaaaccaga cgattttttc ccttgatctg ctttgcaggt
    10981 cagtaaaaaa aacgctgtct tgtacggtat cagcttcata ccacttgttt tccagtatca
    11041 ttcgtgccag cttttgacgg tgcagtagct ttttgaaact gtcgtaacag aagcggtaat
    11101 acagaaaagc gaccaatgca caaacaccag tcgctatcag tatggttatg aagttgtaaa
    11161 gggaaagcgt aaagccattg tctaataagc tgaaatgttc ccagtcggta cgcatgagct
    11221 gttttgtatt taatagcagg ataaccgcta cgaacacaaa caggagtgtc cccattgaaa
    11281 agcgatagac aaggttctta tcgctggctc tgatacggtg tcctttgttt aaaatcattc
    11341 tcataaatca atcactcctt tctgggtatg aaaaaagcag tcaatcgtat agactaactg
    11401 ctttgtgtgc atggatatga agttgtcaaa ctggaattta acgttcactc atatattgtt
    11461 ttatttcatc agaagtcaat tttcgtactt ctgtatgtgg atattcttta tactctccaa
    11521 cattaaacac aggtgtcatt tgtttgcatt tcttgtcttt attctttttc aagaatagat
    11581 gtaaatcctc attcccggcg aatattttat aagatactct gcctttactg ttctctatct
    11641 cataaatacc acatgaactt ttcgttgtat aatcggctgt tcgtaaataa agttttgcaa
    11701 tttccaatga cttaaaagga aaattccatc tttgtaatcc tctgtttggg tcatgttcaa
    11761 tacaaatgca acgtccacaa gttccacaaa tatattgagt gtggttttct aagcagtcca
    11821 agggatttag taatggtgtt attctatttt catcagagta acattcttca cacatttttc
    11881 ttttcgctcc ttatcaaatt ctaatttgtc gctttcttca tacccatatt ataacagttc
    11941 cgtatatcct ctacaacgaa aatctattca gcaagtctat tttttcggtt gtccctgcgg
    12001 tgtatggttc tgtgaagtgc ctgtgttctg attgccttta ttcttcagta caatatcttc
    12061 tgcctttaca taccagtcca catctgcacc cgtataggtt tttcgtgata ccgtatcggc
    12121 tacgggattg acaagctcca cgactgcatt gtaaggaaat tcccttaacg gtacttctgg
    12181 cggtacggac acggggataa ttccaccatg cagactgcac ttcaaatcat agatacgctt
    12241 tttaagctgg gtactcggtg tcccgtcctc attttgcaag aacacatcac gcaccgctgt
    12301 aaattttaat tctccaaatg ttttctcttt gtcaatgaca aatccatttg ataatctcat
    12361 aaattcttca ctcctttact tttcttcaac tgctacaata tcatcagcta ctaatacata
    12421 atcggtatgt cccacatccc cgattgcgta ccctctgccg tataacttcg gattgacaag
    12481 ttttactttc tgttcatact tgaaatgctt ttcgccagcc tgcacgggaa tttccaccac
    12541 aacattttcg cctttctgta cgtcagaata aaggttatag cttcgtctgg ctatgacctt
    12601 gcggttgttt ttatcccttt caaagatagg ctcgctttcg cctgcaaatt caagagttcc
    12661 aaaagactgt gccatatctg gcacgacata tttcatttcc atattgtttt acctcgtttc
    12721 tttctatatt tgataagttt atgattgtaa ttttttattc tggcttgtct gccgtttgac
    12781 agtttcggcg gagaacgtga tttttctttc atcataccgt taccgcctta tgattttttc
    12841 attgtacggc gtttgtaaag atatgttcca gccagtccac cagcagatgt aagcaacatc
    12901 acaagaaatg ccatgacatt tgtactgtcg cccgttttag gactgtcgct aggtctgttt
    12961 ggcttttctg gtgtctgcgg tgtttcgagt ttctctggga cttctggttt ttcattaaaa
    13021 gtaatcgtct gtccctcgtc ctcaatatcc ttatgctcgg taactttctt cggctcgtct
    13081 ggattgctta aatcatacaa ttcttcaaaa gttacaagct gtttgccgtc aagggaagta
    13141 gcgtcaaagg taaaggcaac ttccgctttc atagtttcgc tgtcagcggt aaaggtgtaa
    13201 tcactttcca cacgtttccc attgataaga agttctgcat tttcttcttt caacatctgc
    13261 cagcctacaa gtttgtactg tgtaccgact tccaagccct ctaaggttac ggtatcaatg
    13321 attgtaacgt cttttccagc ttcaatctct ttgttgccgt ctttgtcggt agcagtcgta
    13381 tgtatcttga tgatacgttc tgtaatcaat acagtttgtc cgtcgtcctc aatgtctttg
    13441 tgttccgcaa ctttcacggg ttcgtctgga ttgcttaaat cgtataattc ctcgaatgtt
    13501 accagatttt taccgccaag ctcggacgca ttgaatgtat aagaaatttc cactttcatt
    13561 tcttcatcat cagcgataaa agtatagtca ttttccacac gttttccgtc aatgataagc
    13621 tctgcatttt cttcctttaa catctgccag cctttgagct gatattttgt accttttgta
    13681 agcccgtcta atttgacagt atcgacgatt gttacctctt ttcctgcaag gatagtcttt
    13741 tcgctgtctt tgctggtcgc tgtggtatgg atagagattt ctttttcgta ttcatcagtc
    13801 aaagtcccta aatcaatcac aaggttattt cttgatacca cgatttcaaa aggtgggata
    13861 agttcaaagc ctttgttact atcgcaacgc atttcttcaa tgatgtaagt atcataaggc
    13921 aatgcacctt tgctgtcgtc tgcttcagaa gttccaaacc acacaccgtc ctcgctggtc
    13981 ttgcctgcgt tagtattgtg cttatgagaa gtccattcag cagaagtgga gaattgcccg
    14041 ttatcatcag taactacaac atgactttct cccgtcgtct tgcttgtgat cctaaaggga
    14101 acatcagcaa gacgcttgtg tgtgcctgca ccgattttca ctccctcaat atccccacgc
    14161 ttaatctgat tgtagataga gtgggcttcg tcggttaagt ccacgatttt tccattctct
    14221 gtgattgcaa agtcaatcgg cttcgcaccg tctgtcaagt aaccgtcggg agcttcactc
    14281 tcaacgatac ggaatttccc ataaggtaaa aggtcagcag aagtagaagc cacaccctca
    14341 atatctgtac gaattgtctt taccacttca tttttcttat atagcttgcc ctcaaccaaa
    14401 acagaattgt catttaagga aatgacgtca aaagcagtat ctttcaaagt ggcacttcct
    14461 tgtggtttgg tatcgctcgt ttctaaatct cttttctgaa ttttcacacc gccacggata
    14521 accttgtctg atacggaaaa ctggttactt cccgtcaata cagcaaggtc gccgtcctct
    14581 gtaatttgtg taaggtataa gccttttatc tgttcagact tatcgccagc ctgcatatat
    14641 gcaccgtcca gcaagtagcc gtttggagct tttgtttcct caacagatag tgttcctaaa
    14701 ggaagaatcg ctttgccgtc ctgcatatag aagctgtcgc cagatacctt gtaagcgtcc
    14761 gctaattttg tgatgtagtg agttgtcccg tcactgtctg tttcagcgat tgtctttgta
    14821 acccatgtac gagtagcttc ggcagggaga ttgtctttgt tatagaagcc agcataatac
    14881 ttccatgtaa actctgcacc ctctaaagaa gcgtttccct gcggattgtc tttctgcgtt
    14941 tccatatcaa tcttgaaaag ctcaatcaag gtgtccgtta cttttggtgt atctgatacg
    15001 ttcaaggtcg ctgtctttcc agcttcaact tttaaggaat acacggttgt atcaacttta
    15061 tatcctgctg gtgcggataa ttccctaata tagactgtac ctgcttttac ctctacaaca
    15121 tctgtatttc cgtttttatc agtcgtaagg gtggcaagct gtttcgtgca gtccttatca
    15181 gaaaagacac cataggtcgc accagcgatt gagtaattcc cgttaccgtc tgtaatgctg
    15241 gtattactgg aagtcttttg cagttttgca tttccgacat ttaacttcgc ccagaattgt
    15301 cccaattcct gcccctcgcc agagtagata taaccgccac attcatagcg tcctttattt
    15361 tctttcacaa aggctttagc accagcgaaa acttcgtcct gagttgcttt tggtatttca
    15421 tcataagaag ctcgcacgtt gtcgcattgc cagccaagat gtacgctcaa tctctgccag
    15481 acaacacatt gttccaacag atagacttgc ttgtagttca attccttgtg tgcttcgcca
    15541 tactgtttga catactctaa ggataacgcc acatctgaaa tctggtcggc actcatacgg
    15601 gtgcttgcgt cagctctggt cttgtagcca ttcttaaaat ctgtattgat gtctatacag
    15661 taagcgtcct cgccctcaac agtcaaatgt ccctcgttaa aggtagaacc aatcgaaccg
    15721 tcattcatta ctttttctac gataccgaca cgttcctctg attccgtcca gtattgcttg
    15781 ctttctgcat ggacggcggt actcggtaaa gcagtaacga cagtcgcaaa ggcaagtact
    15841 cccgtacaca atcgtttcaa tatctttttc ataattctaa atgctccttt cattttgggt
    15901 aaaaaaatag acgctcaata ttgaacgtct tacattgaaa agggatactt tttacaagta
    15961 cccctcaaat ctaatattta attgtttgtg ttcccacact ctatatcaac aactactgaa
    16021 acattgatat agttttttat ctctttattt ctgattttat cgccctcgct cgtaaagact
    16081 atatgcttaa aaaagtgcct aaaattaagg atttctacat agttcgtctt tgtagcaaca
    16141 cacaagtctc tatatgtgta gaatgaggga acatatctac aggttgtgcc tcaacacatt
    16201 taaatccgtg aacatttaga taatctaaat cccttgctaa agtagaagga ttacaagaaa
    16261 catagacaat tctttccgga ttcattgaaa caatagtctc taataccttt tcgtcacatc
    16321 cctttctagg tgggtctaca acgactacat tggcagtctt accctctcta tacatcttag
    16381 gtacaatttc ctctgccttt ccaacataaa attcagcatt atgtatattg tttaatttag
    16441 catttatctt agcatctttt atggcatcat ctataatttc tattccataa acctttttag
    16501 ccttttgtgc caaaaataaa gatattgtac ctatcccaca gtaaatatca aaaacagtat
    16561 cagtatcatt taaatttgca tattcaagag ccttatcata caatacttta gtttggacag
    16621 ggtttacttg gaaaaatgat aatggtgaaa tctcaaacac taagtctcct atataatcgt
    16681 ttatttttcc atctccatat ataactatat tttctcttcc tagaatagca ttcgtatctt
    16741 tttgatttac atttacaacc aaagtcttaa atccaggtat attttcctta agcactgaag
    16801 ctaattcttt aagatatgga agtttgtttc catttgctac taatacaacc attacttctt
    16861 tagttgtaaa acctattttt gttactaaat gcctaatcaa ccccgtgtga gtcttttcat
    16921 catatatgct taccttatag gcccttatat atgtttttat tattttaaca attttatcat
    16981 ttatctcatg ttgtattacg catttttctg tcgatattac atcatgagtc ttctttttat
    17041 agaagccaat aattggaata ccattattct tttgtattgg aaattgtgct ttatttctat
    17101 atctatatgg attatccatt cctatagtgt catgaacttc tacatcctct aacttaccta
    17161 ttctcgaaag tacttgttta acttcatttg ttttcatttc aagttgttta ttataatcta
    17221 agtcttgtat ctgacaccct ccacaatccc taagattgtc actacacact cttttcaccc
    17281 tgaatggaga cttttctatt atctcaacaa tatctcccac agcataattt ttctttactt
    17341 tattaatcct aactttaact ttatcatgta ttaatccgcc ctctacaaaa actgtaatac
    17401 cattgtactt tcctactcct actccgcctt gaccaatgtc tactatatct acaatataca
    17461 tctcgttttt cgaaagcata aatcaccctc caatcaatct attatattta aatctttaca
    17521 aacttttttc tttaaattta tattaaaata ttgctattaa ttaaactata ttttttacta
    17581 agctacaata ttttatttta ccaaaaaaaa aggagcttat aaagcccctt agtaaataaa
    17641 tttattattt ttcttataaa actctagttg aacctctata taccacgcct cttgatgcat
    17701 ccacagttac aacttctcca tcttttacta gatttgttat atcagctgca gacacaataa
    17761 ctggtatatc taaatttata cctacaatag ctgtatgtga tgtcattcca ccattctcag
    17821 ttactacagc tcctgctttt tctatataat tgttcatttc agcatcagta gcagtagaaa
    17881 caagtatgtc gccttcatta aagtctacac aagcatttcc attctttatt atacgaactt
    17941 taccttctac tgtttgagta cctacaccta taccttgcac gatttcttcg cttattacat
    18001 gaacctttat taaattagta gttccactta ctcctactgg tactccagca gttataacta
    18061 ctaattcccc attatctata taatcagctt gtctagctgc ctcaattgcc ttttctataa
    18121 cttcatctgt atttcctgca acagaagact taactggata tactccccat gtaagagcta
    18181 atttattcat agtcttttca ttatttgtag tagctattat tggagatttt ggtctgaatt
    18241 tagataccat tctagcagta tatcctgaag aagtagatgt tattatagct gatgcattta
    18301 aatctactgc tgttgtacaa gttgcatggc ttattgcatc tgttacagta acattgttag
    18361 taccattttc ctttagtaat ctatcataat ctaaagtctc ttctgttctt tttgctattg
    18421 tagccatcat ttttactgcc tctacaggat attttccagc agcagtttct ccagataaca
    18481 ttatcgcatc tgttccatca tatatagcat tggcaacgtc tgtaacttct gctcttgttg
    18541 gtcttggatt tcttatcata gaatcaagca tttgagtggc agtaacaact ggctttgcta
    18601 attcattaca tttttttatc atcatttttt gaactattgg catctcttca gttggtatct
    18661 caacacctaa gtcacctcta gccaccatta taccatcaga aacttttaat atttcatcta
    18721 ggttctctac accttcttgg ttttctattt tagatattat ttgtatatca gttgcattat
    18781 tgttctctaa tacttctctt attgctagta catcagatgc ctttcttaca aaagaagcag
    18841 ctatataatc tattccttga cttattccaa actctatatc acttatatct ttaggagtta
    18901 ttgctggtaa atttatctta acaccaggta catttactcc tttatgattt ttaactattc
    18961 ctgaattttc aacaacacaa actatatctt ctccatttat ttcttttact cttaagccaa
    19021 ctaaaccatc atctattagt atagaatctc ctgatttaac gtcttcagca agacctttat
    19081 agcttactgt acacatttct ttagtcccca taatatcttt catagttata gtgaactttt
    19141 gcccttcttc taaaaatacc tctgggtctt caaagttacc tgttctaatt tctggacctt
    19201 tagtatctaa taatatagca actggcttat ttaatttttc tctaactttc tttgccatat
    19261 caattctttc tttatgttct tcatgcgaac cgtgagaaaa gttaaatcta cacacattta
    19321 gaccattttg cataagttga gttaaaactt cctcactttg tgatgctgga cctagtgtac
    19381 aaacaatttt tgtcttcttt acattattta acatatttgc tcctcctgag atattattcc
    19441 acagatttat ttttaatact aaaacttata tagataatat ttttgccatc tcataagctt
    19501 ctttatcaaa tactttcttt tgagctaaag cttcacttat ttctaaatca attattttgt
    19561 tttcttttat tcctacaact ctagctgatt ttccatctaa taataattct actgctctta
    19621 ctccaagtct acttgctagt attctatcag atacagttgg gcttcctcct ctttggacat
    19681 gccccaatac agtgactctt aaatctgctc ctgactcttt tttaagttcc ttttctaaat
    19741 cactagcact tccgactcct tctgctaaaa cgattatact atgtctctta cctctttttt
    19801 gagtagtctt taatcttaga gcaacttcat ctactgtaat ttctacttct ggtactatta
    19861 tagtttccgc tcctcctgca agacctgcat ataaagctaa atctccacag tgtcttccca
    19921 taacttctac tatgttaact ctttcatgag atgatgatgt atctcttatc ttacctatag
    19981 catctataat agtattcatt gcagtatcaa atcctatagt ataatctgta tatgctaaat
    20041 cgttatctat agttcctggt atgcctatag ctgggaatcc taagtcacta agtttttggg
    20101 ctcctgcaaa tgaaccatct ccaccaatta caactaagca atcaatttta tactttttaa
    20161 gaatttttac tgcttttaat ctaccttctt ctgttttaaa ttcttcacat ctggaagatt
    20221 ttaatatagt tcctcccctg tgtataatat ctccaacaga agataagttc atttcagtta
    20281 aatcttcttc tagtaatccc ttatatcctc tattgattcc atatactttg catccataat
    20341 atattgctga tcttacaacc gctctaatcg cagcattcat tcctggagca tctcctccac
    20401 ttgttagtaa tcctatagtt ttcatttttt acctccttgg attttatgtc aattttttat
    20461 tataatcatt gttattgtat tctaatggac tttttttgtc cctatatcac tttttaatcc
    20521 catcaagact aaaaaaatta aatgtcctta aatgtccatt ttgtgatatt atatcacaaa
    20581 acggacaata tttttcatat tattataata tatttagatt tttatataaa aaatcaagct
    20641 tttactttta tgttatcttt aggaagtaac tcttctaagt tatttataaa ttcatcacat
    20701 atacaagtca atgccccggt cattttatat gctttacgtt taccatttat attttcatcc
    20761 atagggtata agtatatact gtcattacct ggatattgtt tggctatttc tacaatatta
    20821 ttagttgtat cagtatcaga catactatct attttcaaat acaatttttt accactttct
    20881 ggcttaatat tttctacatt tctagttctt cctgaattgt agtttctatc tgcaaagtca
    20941 gtatcatcat ttatatcttt tatctctcta gctataagtt ttgcattttc gccttctttt
    21001 atacttaatg ttccttttac atatattata ttatcttcat tcaaaatgac attatacttt
    21061 tgtaataatt gaggaaaaac tattatttct atagcaccat acaaatcttc taattcaata
    21121 aatgccataa tttcatttcg ttttgttgtt ttaatagttt tagttacaat cattccaccc
    21181 attataacat ctgtttcatt catttgtagg tatgactctt cttcctcttt taatgaattt
    21241 aattttccat tatccataga tgttttttct tgtagttctt tttcaaattg tgataaagga
    21301 tgtccactta catacattcc caagacttct ttttcaaggt taagtctctc tctttcttcg
    21361 tactcttgcc ttttaggcaa actgtatatt tgttgaaaat cactatcttc ctcactatct
    21421 ccaaaagcat caaataaaga aatttgacct tgaacatttt tctttctatc catagataca
    21481 ctttctaata aactttcata accagccatc agactagctc tattttcact tatattatca
    21541 aaagctccac attttattag actttctatt actctcttat ttgtatcttt ttggtctaat
    21601 cttttgacta aatctactaa atctacaaat aatccattag attctctttc agcgattata
    21661 ttgtttatta tatttacgcc aacatttttt acggctgcta gaccaaatct tatattgtcg
    21721 ccttcaactg aaaactttga aaaacttttg tttatatctg gaggtaatac atctatttct
    21781 agtgctttac attctcttat atactcaact accttatcag tatttcccat tacactggtt
    21841 atcaatgctg ccataaattc aactggataa tatgttttta gataagctgt ctcatatgct
    21901 aaaaccccat atgcagctgc atgtgattta ttaaatgcat atctagcgaa gtctatcata
    21961 tcatcaaata ttttattagc tatttcctct tctacaccat ttctgataca ccctgcaatt
    22021 tctatattac catcttcatc aaatttacca tgaataaaat attgtctttc ttcttccatc
    22081 acgtccatct ttttcttact catggctctt ctaactaggt cacttcgtcc gtaactataa
    22141 ccacctaaat ctctaacgac ctgcataacc tgctcttgat ataccaaaca accatatgta
    22201 acttccatta taggctttaa tttttcatgt agatatgtta catcttttgg gttgctttta
    22261 ttttttatat atgcaggtat agaatccatt ggacctggtc taaataggga tattcccgct
    22321 acaatatctt caaaattgtc tggttttagc tgtttcataa aacttctcat gccagcactc
    22381 tccaattgaa acacccctag tgtatttcct gatgaaagca tttcatatac tttcgggtcg
    22441 tcataatcca tctttgaaaa gtctattttt tctgtgtaat tttttataac tctatttttt
    22501 tctattaaat caagagtatc tcttataact gtaagagttc ttagcccaag aaaatccatc
    22561 tttaaaagcc caagttcttc aagtgttgtc atagtaaact gtgttgtgat tgcatcttga
    22621 tgtttgtaca aaggtacata ttcatctacg ggattttttg atataacaac tcctgctgca
    22681 tgagtagaag catgtcttag cattccctct atctgttttg atatatttat tatttctttt
    22741 gtttccgggt cttggtcata caattcttta agattaggat ttgtatctag ggccttatct
    22801 attgtcattc ctaaagcaaa tggtatttcc ttggctacct tgtcaacttt attgtagcct
    22861 atatccaata cccttccaac atctcttatt gcagcttttg cacccattgt tccaaaagtt
    22921 attatctggg ctacatggtc atcaccatat tttctcttta cataatctat aacttcttct
    22981 cttctctcat aacaaaaatc tatatctata tctggcatgg atatacgttc tggatttaaa
    23041 aaacgctcaa ataatagaga gtactttatt gggtctatat cagttatttt aagtgtatat
    23101 gctactatcg aaccagccgc actacctcta cctggtccta ctataatatt attttcttta
    23161 gaaaaattta taaaatccca aacaattaaa aaatactcta cataacccat tttttcaatt
    23221 acatctaatt cataatttaa tctctctagt atctcattac taggattatc atatctctct
    23281 tttaatccat taaaacacaa ctcccttaaa taagtttctg gtgtatatcc ttctggaaca
    23341 tcatacttag gaagatgtat agtattaaaa tcaaactcca cattacacat atcagctatt
    23401 ttcacagtat tgtcaatagc ctctaatgca tatggaaata attcttccat ttcttctctt
    23461 gattttaaat aaaactcatc actaccaaat ctcattctat ttgggtcatt taatgttttt
    23521 cccatttgaa tacacataag tacatcatgt attttcgaat cttctttatt tacatagtga
    23581 acatcattag tagcaactag tggtatacca gtctcttttg ataattttac taaaccagag
    23641 tttacttctt tttgctcagg taaattgtga tcttgaatct ccaaaaagaa attttcttct
    23701 ccaaatatgt ctctgtagtc aagagcaaat tgttttgctt tttcataatt tctattcatt
    23761 aaagcacgtg ctacatctcc tgcaaggcat gcagaaagtg ctataatccc tttgttatgt
    23821 tttttaagtt cttccatgtc aactctaggc ttatagtaaa aaccttctac gtatgaagtt
    23881 gaaactattt ttattaaatt tttatatcct tccatattct tagctaacag aactaaatgt
    23941 ccttgatatt tgtcatagtt tgggtcttta tctctcaatc cacgtgcagc tgtatagact
    24001 tcacacccta taattggctt tattccttct tttatagctg ttttgtagaa atctataaca
    24061 ccaaacatac aaccatggtc agttatagct attgagctca tgtttagttc cttagccctt
    24121 tttataagtt ttttcaccct cgaaaaccca tcaagtaaac tatactcagt atgtacatga
    24181 agatgagcaa aatctttgtt cattaaatca cctcctgctt tataatttta attttaccac
    24241 aaatatatgt cctaaaacaa aaacagagac ttttatctca aaataggaat taacttcaac
    24301 atataccatt atatgttata aattaatgct tattctgaga ttgtcccctc aatttattgc
    24361 tatgattttt ttttcaaatc tgttgcaatt tcttctattt ttctaagtct atgattgact
    24421 ccagattttc ctattggtgg ttctaacatc tctccaagtt ctttgagagt catatcctca
    24481 tactcgattc taatcttagc tatctcttgt aaattttctg gcaaactgct aattcctata
    24541 gtctcttgta tgagcttaat attttctact tgtcttactg ctgcatttac tgttttagaa
    24601 aggttagctg tctcacaatt tactatcctg tttacattat ttctcatttc ttttactatt
    24661 ttagtatttt gaagacttaa aagagcgtgg tgtcctccta taatactcaa caaatctgat
    24721 atttgttcac tctctttgat ataaacaacg tgattatttt ttctagccac aattttacta
    24781 ttaaaaccta aagagtttat aagttctttt agagaatctg caaactcctc attattagtt
    24841 acaaattcca tatgatagtt cttttctggg tcgcttatag aacctccacc aagaaaagct
    24901 cctcttatga aagctctctt acatccttca tgcttaatta agttctctga aattttgttt
    24961 atagtaaaaa atccttcttt atcttcaagt atacctaact tttttaataa catttctgaa
    25021 cccatttcgc ttgttaccat taatacataa ctgttatttc tctttagcat ttgattctta
    25081 tttactgaga ttgtagtatt gatattaaaa ttctttttta ataatttaaa tactttacgg
    25141 gctattgaat ttaactctgt tgttatcttt agatttagct tcttatatcc aacaatttgt
    25201 atacttcccc ctgatttaac tagagctgac aattcagcta tattacaaca ttcattccca
    25261 gatataactc ttgctagttc atttttggtt tcagttgaaa aagacatatc tatcacctat
    25321 taactaattt ttctttaacc ttttttttat ttcttgtaag gcaaccttta ttatctcctt
    25381 ttcatcatca tacctagcta agtctactac tctatctagg tggataaatt tagcatcaat
    25441 aaagccttcc tctttttgtg gaatagtatc catattcttt gcttgcatca aataccaaaa
    25501 aactgtttta tgaactgctc tattttcatc ccagttttct ttgaatgtat agtgtatttc
    25561 acctaaatat ttcaatatat ctgcttttac tccagtttct tcacttactt cacgtaatgc
    25621 tgcctcttgg ttattttccc cttcttctac ttttcccttg ggtaacaccc aatctccatt
    25681 gaacttcctt agtaaaagaa tcgtattgcc aaacaggact acaccaccag cactaacctc
    25741 ttctctcatc gatgttcact ccttaaaact aacataatga taaggatttc tacacaattt
    25801 tttaaaatcc ttttttacta acttttgttg taattatgat ttagggctaa ctcaataact
    25861 atgttagata tatactttgc atcatgtctt atataattat tttttatttc aattaaattc
    25921 ttctctacag tttttatacc catctctttt aatttatctt tttgcttttt atctaacaag
    25981 acttgctctg ctccatcttg tttatataag tcaagcattt cttctggcaa tatctcatta
    26041 tttgcgatta cataatctat taaattctca tcagtgtgtt ttactatagc attaacatgc
    26101 tctaatacat tgtacccttc tgtctcacct ggttgagtca ttatatttgc tatatatact
    26161 tttggagcta cagacgattt aatagcgtct acaatcccct ctacaagtaa attgggtatt
    26221 atacttgtat ataaacttcc aggacccata attataatgt cagcatcata aatagatgca
    26281 ataacatcct ttaatggttt tacatctttt ggatttaaaa aaattttatc aatagagctt
    26341 ttttgaattt ttgactcttc aggtatacta gattctccat ttattatatt gccattttct
    26401 aatttggcaa ctaaatttac atcttccaaa gttactggta aaactcttcc tgttatagca
    26461 aaaatttcac ttaatttata tacagctttt tcaaagtttc catacaaccc attcatagca
    26521 gccaaaaaca aatttccaaa actctgacct tttaaaagcc cttctgtaaa cctatattgc
    26581 ataacttcat tcattgttgg ctctatattt gcaagtgcta ataaacagtt tcttatgtct
    26641 cctggtggga gcattcctaa gtcttctctc aatacacctg aacctccacc atcatcagca
    26701 acagttacaa ttgcagttat attttgcgta gtgtgtttaa gacctcttaa aaataccgat
    26761 tgaccagtac ctccacctat cacaaccaca tttggttctc tattttcaac aatagacctt
    26821 tgaaatagtt ttactttttc attttttgct tttttatata taaataacga tacaattaat
    26881 gcaatccaac ctaaaattcc tacaataata agtaatttag ccatgtttgc ctccattatc
    26941 gcaacataga gtctctatgt ttctttacaa ctctatatcc cttattagat aaatcctccg
    27001 ctataagatt tgttatagta actgacctat gtcttccacc tgtgcatcca acaccaatta
    27061 ctagatgttg ttttccttcc tctatatatt gaggtactaa aaaatgaatc atatctaaaa
    27121 gtttcacata aaattcttca ctgattttag aattcataac ataatctcta acttctttat
    27181 catcaccagt tttagctctt aactcttcaa cataataggg atttggaaga aatcttacat
    27241 caaatactaa atctgcatca gcaagtatac catgtttaaa tccaaaagat actacagaaa
    27301 tagttaggtt tggattatct tcacctgaag aatatatttt ctttatttct tccttaaggt
    27361 ctttaggttt catgttagtt gtatcaatta tacatgtaga taactccttt aaaggttcca
    27421 ttatctttct ttccattttt ataccttctg gaatctgcat atcttttgcc aatggatgat
    27481 ttcttcttgt cattttatat ctctttaaca atacatcatc attacaatcc aaatatacca
    27541 tttcatattc ataattttct ttttctaaat aatttaagct ttcatgaagc gcttcaaaaa
    27601 actttctccc tcttatatct atccctagag caactttatc aatacttgaa tttggttgat
    27661 aacataattc tgcaaattta gttatcaaag caggaggtag attatctaca caataaaatc
    27721 ccatatcctc taaagctctc attgtctcac tttttccaga tcctgaaaga cctgtaacta
    27781 taacaaattt cattgctaac tcctcccttt tatcttatgt ttattatatt ataatgtttt
    27841 ctactaacga tatatccaga ttagagtcag atatagtctt catagctagt tcaaaatcac
    27901 caactctttc tggacaatgt gcatctgagc ctattataaa tttattttct agccctttta
    27961 ttttatttaa ttgatttaca ttcaaaaaag aatggctact atttatctca agtctagtat
    28021 ttgtcttttt tgctgtcttt gctacttctt ctatatacac atcgccttta tctcctggat
    28081 gagtaattat aaaaatatca ttattactta tcgcatttat tacagctttt gtattatatt
    28141 cttttgcttt ttcagtttta aaaatatagt tattacaatg atttaataag cttcttaatg
    28201 atgttggagt agaaccaaaa tgatatccag ccataatata atcaaaatct ctaataaatt
    28261 tatcatccat atctatattt cctttatcat ctaatatgtt acactccata cctaaaagta
    28321 tatttatatc agtgtactta tcatttaaat aatctacttc ttctctcatt ttgagaatat
    28381 cttttttctt tacaccatat gcaatatgtt tataactatg gtcagatatt cctattgttt
    28441 ttattccttt agaaatggct acctttacat tatcctcaat agtccctttg ccatgactat
    28501 ataatgtatg tgtatgataa tcagccagta ttttcatttg ttaatcctct ccaagtattt
    28561 tgacttcttc ttccaacata accccaaact tggcatatac agcacttttt ataacatata
    28621 ttaaatccaa aatatcttta gcacttgctt ctccttgatt gactacaaat ccacaatgct
    28681 tctcagatac ttgtgctcct cttaaagtaa gacctctcaa tccagtttct tctattaatt
    28741 tacctgcaaa atatcctgtt ggtctcttaa atgtacttcc tgcactagca aaatttaatg
    28801 gctgtttagt tattcttctc gtcgctaaat catccattaa actttttatt tcatcataat
    28861 ttccttcttg taattccaat tctgctgata aagctatata tccgtttttc gatattatac
    28921 tttttctata cccaaattcc atctgttcat ttgataattc aaatatattg ccttccatat
    28981 ccatcagtct tactgacttc actatgtcct tcatttcacc accatatgct ccagcattca
    29041 tggctaatgc tcctcccaat gtgccaggta ttcctgatgc aaactcaaac ccttttaatt
    29101 cttgcttttg gagagctttc cctaaaactg ataataaagc tcctgactga gcagtcatcc
    29161 tagtatcatt tatctcataa gaattgaaat tatcagctag ttctattacc actcctctta
    29221 ttccaccatc tttaattaaa atgtttgaac catttccaat tattaaatac ggaatagatt
    29281 cttcttttac caacttaagt acatttttta attgttcttc agttctaggt ctaactaata
    29341 tatctgctgg tcctcctacc ctaaatgaaa tatgtttttt cataggttca tcgactttta
    29401 tatcctcttt acttaatata tttaataaat ttatatatat atcttgatta ttcattgtat
    29461 ttcctcccaa attatactga actttagctg tcattattat ttaaattaca ttagtatata
    29521 gtattaacta tattcaataa tatatgattt tgcttatcat atggatttta tattttaagc
    29581 ttcttaatta caaactatat tcaataaata tataataaag taaaaaaaaa aaaataacaa
    29641 catataaaag aatataaata atttaaaaaa agcatcaata tcactgatat caatgcttta
    29701 aaaggcaatt taattcgtat tatttatcta actatttttg acatagcaaa gataataaat
    29761 ccctccaact actatggaac ctccaacgat atttccaagc gttacaaata ccaaattagt
    29821 tataaattga accatagtta tatttgctcc taatgccatt cccattggta taaaaaacat
    29881 gtttgcaaca ctatgttgga atccacataa tacaaatagc attattactg tccaacatga
    29941 agccaatttt gacattatat cttgagatgc tgtagccatc catacagcta aaacgactag
    30001 aatattacaa agtattgctt ttaaaaacat tgatgctata gttgaattaa ccttagcttc
    30061 tgccacagct atagcttttg tagctgcatc tcctgtcaat gtagaagaat aaaacacaag
    30121 tgcaactagc aaaattgaac ctactaaatt tgcaaaataa accagtcccc agtttcttaa
    30181 catttttcct aatgttattt ttttgtccat aagtgcaata gccattaagg tgtttccagt
    30241 gaataattct gctcctgcca ctactacaag cataagacct actggaaaga ccatagcact
    30301 taaaaagcta gctacccctg ggtctatctt gccaaaagtt tgactaacta tcatactccc
    30361 caatgcccca aaacctataa atgctcctcc aaataaacct aatagaattg cgttttgtgt
    30421 cgaaatattt gcttttttaa tgcctgcact tatagttgct tgtgcagttt ccccaggtgt
    30481 caagaatcct ttactcataa atccttcccc cttaaaaatt atactttccc ttgtcttttt
    30541 atggcaataa ttatataata acaatatgat atataataaa ttttattaac ataaaaaata
    30601 tactatatac ttatatatac ttgtctcata taattatact atttattata taacaacttt
    30661 gttaatttcg aaataattta tattgaattt gaaaaattta ccttttgatt atttatttta
    30721 ctttttaatt attgaggtat tatatataat agatatatgt ttgtgttatt atatataatt
    30781 acttatttta ataaatattt gaaggaggga attttatgtt tgatatatca tttttcgaaa
    30841 tgtcaatata tgaaatagca gttactacaa tatatataat taatttcatg gttatactaa
    30901 accttatctt tagagaaaaa agaaacataa atacaacttt aacatggctt cttatattag
    30961 tattgattcc tgctcttgga ttcatacttt atatagcttt tggcagaaat atttcaaaaa
    31021 acaatatgtt tagattgaaa gaaaaggatg ataagataat caaaagtaat atactagata
    31081 ctcaggttaa actccaatct acatctgaaa ttgattcaga tatacatcaa cataaggata
    31141 tgatttatgc attggctaat tcaaataatg ctcattatac caataataac gatgtgtgga
    31201 tttatgctga atctagtcaa ttttttaaca gtcttcttga agaacttaaa aaagctaaaa
    31261 aatatataaa catacaattt tacattttca aagatgacaa aatcggaact gaaataatag
    31321 acattcttat agacaaagct aaagaaggtg ttgaagtaag acttttattt gatgcagttg
    31381 gtggtagaac actaaaaaat agtacacttt ccagacttaa agaaagtggt gttaaagttg
    31441 gaagcttctt cccatcattc ttgaaaattg taaactttaa cttaaactat agaaatcacc
    31501 gaaaaattgt tgtcattgat ggtaaggtag gatttgtagg tggatataat gttggtgatg
    31561 aatatttagg tagaaatcca aaatttggtc tatggagaga tacacatact aagcttactg
    31621 gtgattgcgt aattgaccta aatatgagat tcatccttga ttggagatat acaactaaag
    31681 aagacttaga tttagaaaag tactttatag aagaagatac aaattctaat catccttctg
    31741 aaaatattgg gattcagata gtatcaagtg gtccagatat atcagaactt gatgagatta
    31801 aatatggtta ccttaaaatg attcagaaag ctagaaagta tatatacata cagagtcctt
    31861 atttaatact tgactcaact tttatagata ctttaaaaat agcttgttta tctggtgttg
    31921 atgtgagagt tatgattcct tctaaacctg accatccctt tgtatactgg gcatcatatt
    31981 catatgctgg agaactttta aagtttggag ctaaaatcta tacttatggt caaaatgcat
    32041 ttttacatgc taagacaata gttatagatg actctatatg ctctatagga acagctaata
    32101 tggatatcag aagttttgag cttaatttcg aagttaatgc atttatgtac tcttcaaaaa
    32161 aagcattgga acaaagaatt atatttgaaa atgatatttt aaattctaag gaaataacat
    32221 tagatatata taattctagg tctacttata taaaaatcaa ggaatcaatt tcaagactat
    32281 tatcagcagt tttataaatc ttttatttta taaaaatttt acattttggt ttatttttta
    32341 aagtttttta tatgtattat ttttttttta ttgaatttag ctcatttttt ttattttttt
    32401 taactattct gaattatttt atattataat agactagtat agtttttatt tttaataggt
    32461 aacttttttg cattgttttt ataaataaag aaattgttgt atattattct ttctttattg
    32521 ttttggtttt gttcacccac ataatgttgg ggtcaactca tggttaatta ttttatgaaa
    32581 aataataact ttaaaaagaa aagggggatt tgttatgtgc gattttattt cacacaacaa
    32641 gcaattattt gacgaactag atatatttat tgactctctt gcaacaaagg aaggtgcgtt
    32701 aatacaagtt ctacatgaag cccaaggtat atttggatat cttccaaaag aagttcaact
    32761 tcatgttgct agaaaacttg gagtagctcc tgcaaaggta tatggggttg ttacattcta
    32821 ttcttatttt actacagaac ctgtaggtaa gtataaaatc agtgtctgtc taggaactgt
    32881 atgttttgta aaaggtgctg acaaaatctt aagtgctttt gaaaaacagc ttggcataaa
    32941 agttggagaa actactagtg attttaaatt ttctttagaa ggtttaagat gtttgggggc
    33001 atgtggttta gctccagttg ttactgtaaa tggtaaagtt tatggtaaag tgaaacctga
    33061 ccaagtaagc gaaatattag atacttatag agaattagaa ttgaattgtt aagaggggtg
    33121 aataaataat gcgtaaagta aattcatttg atgaattaaa agttttagct gatgagctga
    33181 aacctaatct tagcttaaga aaaaattatt ctaaggaaaa tgtattaaga agagaattac
    33241 ttgtttgttg tgatactgga tgtacatctt caaacagtct agaaatagtt agtgaattag
    33301 aaaatgaaat aaagaaatca ggaatccaag ataaagttag tgttcgtttg acaggttgtt
    33361 ttggtttctg tgctcaaggt cctattgtaa aagtttatcc tgataacgtt ttctacgtaa
    33421 aagttgagcc atctgatgct gaaaagatag ttcaaagcca cttaattaga aatacagttg
    33481 tcgaggaatt attatatgag gaagaatctt taagtaaaaa agttgaagaa caagaagaaa
    33541 tgtctttcta caaaaaacag ttacgtatag ctttaaaaaa ttgtggtctt atagacccag
    33601 atagtataga agaatatatt gccaatgatg gttatttagc tctaggcaaa tgtttaactt
    33661 ctcttactcc tcaagaagtt attgcagagg taaaaacttc tggccttcgt ggtagaggtg
    33721 gtgcaggttt ccctactggc tctaaatggg aagctgcttc aaaaaatcca gctggtccaa
    33781 cagataaaaa gtttgttgta tgtaatgctg atgaaggtga cccaggtgca tttatggata
    33841 gatctgtact tgaaggtgac cctcatagtg tactagaagc tatggcaata tgtggatacg
    33901 ctataggttc tgatacagga tacatataca taagagcaga atatccaaaa tctatagaaa
    33961 gattaaaagt agccatagct caagctgaaa aatacggttt acttggcgaa aatatcttag
    34021 gcactggatt taactttaaa ttagaattaa aatatggtgc aggtgctttc gtttgtggtg
    34081 aaggtacagc gctaatgcat tcaattgaag gtagacgtgg tgaacctaga atgaaaactt
    34141 atagttcttc taagagtggt ctatggaaat ctcctacttg cttaaataac gttgagactt
    34201 ttgctaacat acctgcaatt atacttaagg gtggagattg gtttgccaac ttaggtactg
    34261 aagattctag tggtactaaa gtctttgctc ttggtggaaa agtagaaaat gtaggacttg
    34321 ttgaagttcc aatgggtact actttaagag atattgtatt tgaaattggt gggggaatcc
    34381 ctgaaggtaa gaaatttaag gctgttcaaa caggtggacc atctggcgga tgtataccaa
    34441 ctgaacattt agacactcct atagactttg gttcattaag ttctatcggt tcaatgatgg
    34501 gctctggtgg tatgcttgtt cttgatgaat ctgactgtat ggtagatata gccaagttct
    34561 tccttgagtt tactgttgaa gaatcttgtg gtaaatgtac accttgtcgt ataggtacta
    34621 caagattatt agaaatatta actaaaatta cagaaggtaa tggtactcta caagatttag
    34681 atgacctaga aaaccttgct gaaactatac aaactgcttc attatgtggt cttggtaaag
    34741 ctgctccaaa ccctgtttta agtactcttc aatatttcaa agatgagtat atagctcatg
    34801 ttgtagataa gaaatgtcct gctggtaaat gtcagaactt actttcttac tttataacag
    34861 atgactgtaa gggttgtaca aaatgttcta gagtgtgtcc tgctggttgt ataacaggtt
    34921 ctgttaagga acaacataca atagatactt ctaagtgtct aaaatgtggt gcttgtatag
    34981 ataattgtac atttaacgct ataatcaaga aataacttat ttggaggagg aataacaatg
    35041 agtttagtta atttaactat taatggcaaa cacgtttcag cacctagtgg aacttctatc
    35101 ttagatgctg cgaaattaat aaatataaaa atacacaacc tttgtcattt acatatgaat
    35161 gaaatagata agcttgacac ttgtgcttct tgtcgtgttt gtatggttga gacagagaga
    35221 ggattagttc cagcttgtgg aacagttata aaggaaggta tgaaagttca gactaatagt
    35281 gctaaagcat taaatgctcg tagaactatt gttgaattat tgttatcaga ccatccacaa
    35341 gattgttttg tctgtgaaaa aaatggagat tgtgaattac agactatagc tgctgattta
    35401 ggagtaagaa aaataagata tcaaggttct aaatcttttg caggtaaaga tacttctact
    35461 aaatctttag ttaaagacca ttctaagtgt atattatgta gaagatgtga gactgtatgt
    35521 aatgacatac aaacagtagg agcattatct ggagttaatc gtggatttaa tactttagtt
    35581 agtacattct ttaactctga tatggttgaa acagagtgta cattctgtgg tcaatgtata
    35641 tctgtctgtc caactggagc attaacagaa gtagataatg tacctaaact ttgggatgtt
    35701 ttaaataaaa aagaaaagac tatagtagtg caagttgctc ctgctgtaag agttgctatt
    35761 ggtgaagagt ttggattaga accagggtca atctctacag ggaaaatggt agctgcttta
    35821 aaagcacttg gatttgaaca tgtatttgat acaaactttg gtgcagattt tactataatg
    35881 gaagaagcta ctgaatttat agaaagaatc caaaaaggtg aaaatcttcc tatattaaca
    35941 agttgttgtc ctgcatgggt aaacttctta gagcacaatt atccagacaa gttaaactta
    36001 gcatctagct gtaagtctcc tcaaggtatg tttggttcta tagctaaaaa ctactatgca
    36061 cctaaaatat taggaatcaa tcctgaagaa ctttatgttg tatctgtaat gccttgtgta
    36121 gctaaaaaat atgaagcttc aagagaagaa ttaagtgaat ctggaatact agatgttgac
    36181 ctttctataa ctactagaga gttagctaag atgataaaag aagctgcaat cgatttacct
    36241 aatcttcaag accaagattt tgataatcct ctaggaaaat ctacaggtgc tgcatctata
    36301 tttggagcaa gtggtggagt tttagaagct gccctacgta cttcatatga gaagataact
    36361 aataagactt tagataatgt aaacttcact aatgttagag gtcttaaagg aattagggaa
    36421 gcaagtatag atgttgatgg aactacagtt aatgtgtgta ttgtaaatac acttaaaaac
    36481 gctagaaaga ttatggataa ggtcagaagt ggagaatgta aataccatat catagaagtt
    36541 atggcatgtc ctggtggatg tgttggaggt gctggtcaac cttatcacca tggtaatact
    36601 gaaatagttg atagacgtgc aaatgcgtta tatgaaatag atagaaataa ggctattcgt
    36661 aaatctcatg agaatcctga tttacaagct atttataaag acttctttgg agaaccaaat
    36721 agtgatgtag cccataaata ccttcatact cattactttg ataagagttg tgtctatgga
    36781 gagtgtccac aagaatgtgc ttgtgaagaa gctaagtagt cataacaaaa tataaaattt
    36841 attcttaaaa aaggattgtc ttaaaatact tttacgtaat ttaagacaat ccttattaat
    36901 ttcacaaatt aaattatatt tctaaataga cttattcttt aattaaccta tctattaatt
    36961 aaagaatacc tgccattctc ataagttgtt ttgcatttgt agttttacat cttccatctt
    37021 ttatcttata gtcaaaatga attttatcgt ctacatagta ctctgagaaa tgatagttta
    37081 caacttcaac atctccacta cctgaaaggt cacatagctc aaagtcatgt gttgtcacca
    37141 tacttataac ccagggtttt gataatttct ttactgcctc acttgctcca ataattctat
    37201 cagcagagtt agttccctta aaaatttcat ctactagaac caacattggc agttctttta
    37261 aactatattg aatcattgat tttattctaa gaatctcagc atagaaagtt gatattcctt
    37321 gacttacatc atcttgtatt ctcatagaag taaatatagc catacaggtc gcatcaaaac
    37381 tcttagcgca tactggagca cctgcatatg ccagcactaa gtttacaccg atacttctta
    37441 aaaatgttgt ctttccagac atatttgaac ctgtgataat acaagtctga gaatttaatt
    37501 gtatcgaatt tgctatgaca cttttttctg ctattaatgg gtggtatacc tcttcaactt
    37561 tcaatcttgg agtatcttca tattttatta ctggaaaaca tgtattttcc tttacatgag
    37621 aaacaactgt taaacttatt agagcttcaa attctccaat agattcaaac caatctctaa
    37681 tttgatttcc atatatacct ttccatcgct ccaaagcttc tgcacaatga tagttccaca
    37741 tcaaaacacc acaggcaatt atatatagta tctgattata ccttaggttt acagcatttc
    37801 ctattgaatt taattgttta acacctcttg aaactccact tcccttagaa agtttatctt
    37861 gtaattcttt caaatatgca ctctcaaacg tctctttttc taaaacctca aacatttttt
    37921 catatacttg tatacttcta ctaaatgaaa ataatggagc aagagtttgc ataagtcttg
    37981 gatatccaaa accactaaac cctaactgga ttataaaaag taaaaaaaca ggtaaaacag
    38041 gtaaaaatcc taacatacaa aatataaaag ataagattgt tgcagttggt aaaccccaag
    38101 taaaaatatg catccatttt ggtatataca cattcttatt ttctccatat tctataaacg
    38161 attctatact actatctgaa ttgttttttt gctctttacc aattatatta ctgagtgttt
    38221 gaatatgaat agaaaaatca tcttttgata aaagttcttt tatagctctc tgtctttcta
    38281 agattacatt ctcatctgga ttttcattcc acaaatattt ggctaaaaaa tttttcccat
    38341 aagatgtatt agctacacag atatattgat acaatgatgc tcttccaaat aagtctaaat
    38401 cttttgcttg cgaattttca tcttttaagt attctttacc atctatttta aattccttcc
    38461 aaccatctcc aaatctctta atatacttat ttaatacttc gctcttactt ttaaaatatg
    38521 tttcttcttc ttttacttta ctatgaataa ctaagagtgc tataaatatt attattgata
    38581 aaactccaac aaaaatacct actatatttt tattgtaaaa tccaatagca aaccctgcta
    38641 tcactatcaa aaaagatatt aatcttgctg tacttatgtt atttgacttt ttacttaaga
    38701 gcaattcttt ttcagtacta ctttctaaaa gtttactaaa atattctatt cccataaaaa
    38761 attccaactt tcttgttata taatgaaact caaatataaa attaatctag tattattata
    38821 atctaacact gtactttaaa ttatccttat ataatatatc ttattaataa acattatata
    38881 tatacaactt gattttaatt tataaggtgt aggacataat cctaatcaat atttaattaa
    38941 atgatgtgta gttcactatt attcagtact acttagtatc gattaatttt gataattttt
    39001 tagtaaattc ttgagctgca tcgtatccca ttcctctttg tctaaaattc attgctgcta
    39061 cttctaatat catagcagta tttcttccag gtttaacagg tacaactaat ttctctacat
    39121 taacaccaag tatttcttca tattctttat ccagtcccag tctatcataa tacttagttt
    39181 catcccaagc ttctaaatga actactaaat ctatcatttt agaatttttg attgccccta
    39241 ctccatataa acttctaaca tctattattc ctattcctct tatctcaaga aaatgtctta
    39301 ttagttcagg tgactgaccc acaagcatac tttcatctaa ttttcttatt tctacagcat
    39361 catctgcaac taatctatta cccctttgaa tcaattctaa tgctgtttcc gactttccta
    39421 tactactttc accttttatc agtacaccta taccataaat atctactagc accccgtgaa
    39481 ttgttgtgtg tggtgctaac ttattatcca aatagtttga cagtctattt ataagtctag
    39541 tggtatttct atttgtgctc aaaagtattc ttttatattt tttagccttt tcaattacat
    39601 ctggcttgat ttccaagtct ctagaaatta ttaacgctgg tatttcatat gagaaaaatc
    39661 tatctagtac ttcttcccga atatgactat ccattaatcc aaaaaaatta tattctgtct
    39721 ttccaactat ttgtattctt tcatatgcaa aataatcaaa atatcctgca aactgtaatc
    39781 ctggtctatt tatatcttga gagtagacat aataatctac atcatcaggc atgtatacta
    39841 cttttaactt caactctttt attatctctc ttattgatac tttattgcta gtttccatta
    39901 attttcttcc tttctaaaaa aattataaac attatctgca atgcttttat tcattccatc
    39961 tacttctaaa agttcttcca tagtagcttt ttttatagca tctacatctt taaagtgatt
    40021 taataatgat ttctttcttt tttcacctat tccttgtata tcatctaaga tagattttgt
    40081 caaagcttta tttcttagac ttctatgata tgttattgca taattatgaa cttcttcttg
    40141 tatactagca ataaatctat ataaattagt tgttttatct agttctattt ctttttcttt
    40201 gcatatcaat cctttagttc tatgcttatc atctttgtac attccccaaa gaggtatatc
    40261 tacatcattg agttctagta ctttttttac tgcactaact tgtccttttc caccatccaa
    40321 caatatcaag tcaggtaaat ttccatgttt taatcttcta tctacaattt cagccataga
    40381 atcataatca ttaggtccaa taactgtctt tattttatat ctcctatatt ccttcttatc
    40441 ttttttagca ttcgtataca ctaccataga accaatcgaa tctacacctt gtatatttga
    40501 tatatcataa gcctctattc ttattggcaa cttttctaga tttaatattt gctttaattc
    40561 ttccaatgct ccaatacttt tttcatattt tcttttattc atatcagaaa atttttcaag
    40621 atattctaca gcatttttcc taaccatttc aactaagctt ttcttctctc ccttttgagg
    40681 aactcttatt gttacttttt gccccttttt agatgacagc cattcttcta atatagaact
    40741 atcttctatc tcatcttcta taattaattc tttaggtata tactcttgtt cattataaaa
    40801 ttgttttaca aatgaactta atatagaagc tcttggacta tccattaccc cttctaatat
    40861 aaaatgttcc ctacctacaa tcttaccatt tcttataaaa aatacctgga cacaagcttc
    40921 attatgagct cttgccattg caaccacatc ttggtttaag tcacttacag tagcatctat
    40981 tttttgtttc tgtatcatct cttcaaggct ctttatctta tccctatata cagcagcctc
    41041 ttcaaatcta aagttcatag aactctcatt cattttttcc tttaaaagtt ccatcaattt
    41101 ttcttcttta ccagataaac acattataat ctcttctatc atttttccat actcttcttt
    41161 agaaacattt cctgtacaag gtcctaaaca tttatttatg tgtagattta aacaaggtct
    41221 tgtcttattc tttattgctt tatctatatc tattttacag cttcttattg gatacgtact
    41281 acttataagc tccaaggtat cattcacagc agttatattg gtatagggcc caaaatactt
    41341 tgccttatct ttaagaactc ttctaacttt taagattctt ggataatctt cattcgtagt
    41401 tacttttata tatggataag ttttatcatc tctaagcact acattatact ttggtctgta
    41461 tctttttatt aaattacatt caagtattaa tgcctctaac tctgaatccg ttataatata
    41521 ctcaaactta tatatattct taaccataga ttttacttta gatgtatggt tttttgaaga
    41581 ttgaaaatac tgccttaccc tattttttag agatatggct tttcccacat atattatatg
    41641 gtcgtatttg tctttcatta aatatactcc gggctcagaa ggtaattttt ttaaatgctc
    41701 ttgtatatca aacatctcgc cctccaaaac attaaatttt atactaaaat tataccctaa
    41761 aatatgaatt ttaaaaagtt atacaatttc cagtgcttta aacaagttaa agcccatatt
    41821 cccttctata attgatttga aaacaatttt aaccatgaag agtaatatgg actttacttt
    41881 gtattactat ttacaactta tatttgacta atttacttat aacaaaacag tttatcgtat
    41941 atctgctcta aaatttttca caatttatat aacttaagaa aaatatttct ttaagaattg
    42001 acctgtataa gaaccatcaa ctttagatac ttcttttggt gttccagttg caactatagt
    42061 tccaccctta tctccgcctt ctggtcctaa gtctattaca taatcacaag tctttataac
    42121 atctaaatta tgttctatga ctataattgt atttcctgta tctgctagtc tttgtaatac
    42181 ttggattagc ttgtctacat ctgccatatg aagtccagta gtaggttcat ctaatatata
    42241 caaagtcttt cctgttggtc ttttactaag ttcagcagct aattttatac gttgtgcttc
    42301 tcctcctgat aattgagttg aaggctgtcc taatttaata tatgaaagtc ctacatccat
    42361 taaagtttct aattttcttt ttatatttgg tatattttcg aaaaactcaa cagcttcttc
    42421 cacattcata tctaatatat cagatatagt tttatctttg tattttactt gcaatgtttc
    42481 tctattgtat ctttcacctt tacaaatttc acaaggaaca tatacatctg gtaagaaatg
    42541 catttctatt tttattattc catcaccctt acaagcttca catctaccac cttttacatt
    42601 aaaactaaat ctaccttttt tataacctct tgctttagct tcattagtag atgcaaaaat
    42661 atctcttata aaatcaaata cacctgtata agtagcagga tttgaacgag gtgttcttcc
    42721 aataggactt tggtctatat ttataacttt atctatactt tcaattcctt ttatctcctt
    42781 atgcttacca gctctttgct taagtctatt cactttactt gcaacacctt tgtaaagtat
    42841 atcgtttatt aatgtacttt ttccagaacc tgaaacacct gttatgcatg taaacttacc
    42901 taatgggaac tttacatcaa tatttttcag attattttct gatgctttaa ctatttctat
    42961 aaaacttcca tttccttctc tagtagtctc aggaagcaat atttgttttt taccacttaa
    43021 atattgaccc gttattgagt tctcattttc aattatttca tctaaagtac cctgtgcaac
    43081 tatttcacca ccatgtatac ctgcacctgg accaatgtct ataacataat cagcttctct
    43141 cattgtgtct tcatcatgct ctacaacgat taaggtattt cctaaatctg ttagatgtct
    43201 aagagtagtt ataagcctat cattatctct ttggtgaagc cctatacttg gctcatcaag
    43261 tacatataaa actccaacca atgcagaacc tatttgagta gctaatctta tacgttgcgc
    43321 ttctcctcct gataaagttc cagcttttct tgataaattt aaataatcaa gacctacatc
    43381 tcttaagaac atagctcttc cttttatctc ttttataatc tcatgagcta taaatctctg
    43441 tttttctgta agatttatat tttccataaa gtcaatcaat tcatttacag ataagtttgt
    43501 aacttccatt atattttttc catcaactaa aacagataaa acttcctttt taagtctcat
    43561 ccctttacac tttggacatg gtctctctgc catgtattct tcaatcttat ctctcatgta
    43621 atctgaatta gtttctctat atcttctctc taagtttact attacacctt caaagtatga
    43681 tttataattt ctagttcctc caaattttga ctcataagta aactctacaa ttatattatc
    43741 tttaccataa agtaattcct ccacaaaatc atctggtaaa tctttaaacg gtgttgtcaa
    43801 agatacatta aaatgctctg ctaaactttt tatcatttta ctgtaataag tgtcatcatt
    43861 aacacctgtt gaaccccatg ctgccactgc accttgtttt attgataaat ctttgtttgg
    43921 tactactaat tctgggtcaa cttctttact ttccccaaga ccattacaaa catcacaagc
    43981 accaaaggga gcattaaatg aaaacattct tggagataat tcttctatgc caattccatg
    44041 ttctgggcat gcaaatttag ttgaaaaaag aatttcttct ccatctatta tttgggctat
    44101 tacaagacca tcagatagct taactgcagt ttcaattgaa tctgctagtc ttgattctat
    44161 tccatcttta attactattc tgtccactac aacttctata ttatgttttt gatttttatt
    44221 taagattata tcatcactaa cttcatagtt ttcaccatta actctaactc ttacaaatcc
    44281 ttcttttttg atattatcaa agactttttt atgtgtacct ttttgtcctc taacaattgg
    44341 tgaaagaatt tgtaatttcg ttctatctgg aaaatctagc attttatcaa ctatttcttg
    44401 aatagtcatc tgacttattt tttcaccaca tgtagggcaa tacacatctc ctactcttgc
    44461 aaataatagt ctcaaataat catatatttc tgttactgtt ccaaccgtag aacgtgggtt
    44521 ttttgaggta gtcttctggt caattgagat agctggtgat aaaccctcta tatattctac
    44581 atttggcttt tccatctgac ctaaaaattg tcttgcataa gcagatagac tttctacata
    44641 tcttctctgt ccttctgcat atattgtatc aaatgccaaa gaagacttcc cagaccctga
    44701 caaacctgta aaaacaataa atttatctct tggtaattct aaatctatat tttttaaatt
    44761 atgttctttt gctcctctta ttataatttt atcttccata atgttgtttt tacctttcta
    44821 tttttccaat ttttcttcta attgtttcac tttatctcta agttctgctg ctctttcaaa
    44881 ttgtaagttt tgagcagctt ccatcatctc tgattttaat ttatctatat tagctcttat
    44941 ttcgtcttta tcatctgtat cagatattcc atatacaact tcttcctctg caaccttagt
    45001 agcttctata ctatctctta tatttttctg tatagtttta ggaatgatat tgtgctcttc
    45061 attatataaa ttttgtatat ctcttcttct ctttgtttca tcaatagcat tttgcattga
    45121 gtcagttatc ctgtctgcat acataattac tcttccattt tcatttctag ctgcacgtcc
    45181 aatagtctgt attaaagctg tttcggaacg taagaaacct tctttgtctg catctaaaat
    45241 tgctataagt gaaacttctg gtatatccaa tccttctcta agtaagttta ttcctacaag
    45301 gacatcaaac ttccctaatc ttaaatctct tattatttct gttctttcta atgtaactat
    45361 atctgagtgt aaatatttaa cttttatccc tatttcttta agatagttag tcaagtcctc
    45421 actcattttt ttagttaaag tggttataag cactctttca tttttttcta tagttttagt
    45481 tatttctcct accaaatcat ctatttgatt atttataggt cttacttcta caattgggtc
    45541 taaaaggcca gttggtctta ttatctgttc tgctattgtc tctgagtgtt gaatttcata
    45601 aggccctggt gtagcactta caaacaacat ttgatttata tttccttcaa attcttgaaa
    45661 atttaatggt ctattgtcaa gtgcagaagg taatctaaaa ccattctcta taagtgatgt
    45721 ttttctagac ctgtctcctg catacatacc tcttacttgt ggtatagtga catgtgcctc
    45781 atctacaatt atcaaataat catctgggaa gaaatccatt aaagtatatg gtctttctcc
    45841 ttctgacctt cctgtaatat gtctagaata gttctctatc ccctgacaaa atcctatttc
    45901 ctttaacatt tctatatcat acttagttct ttgttcaatt ctttgtgctt ctaatagcct
    45961 atcattttcc ttgaaaaatt taatttgttc ttgaagctcg ttttctattt ctacaattgc
    46021 cttttcaatt ctttctggcg ttgttacata gtgagatgct gggaatataa caacatgatt
    46081 tctagtacca acaatcttcc ctgttacata atcaatttct gttattctat ctacctcatc
    46141 accaaaaaat tctattctta ttgctttttc atcattacta gctgggaata tttctagtat
    46201 atctcctcta actctaaagg tacctcgtgt aaagtttatg tcatttcttt cgtattgtat
    46261 ctctattaac ctttttatta catcatctct gtctctttgc atacctggtc ttatagataa
    46321 cataagttct ttatagtctt ttgggtcacc aagtccatat atacaagata cagatgatat
    46381 tattatagta tctcttctct ctaaaataga tgctgtagca gaatgtcgaa gtttatctat
    46441 ttcatcattt atgcttgcat ctttttctat ataagtgtca ctgtgagcta catatgcttc
    46501 tggttgataa taatcatagt aacttacaaa gtattcaact gcattgtctg ggaaaaattc
    46561 tttaaactca ctgtaaagtt gtgctgctag agttttatta tgagccatta ttagggtagg
    46621 tttcttaact tgttgaatga tatttgccat tgtgaatgtt tttcctgaac ccgttacacc
    46681 taataatgtc gaaaatttct catttctatt tatagaatcc actattgatt taatagcttc
    46741 tggttggtca cctgtaggtt tgaagtctga ttttatttta aaatccatag tatcactcct
    46801 tttttcgaac attagttcct gacatgtatt attatatcat acctttataa aattgtttaa
    46861 gttattttaa atattttacc catttaaatt ttacttaaat ctaaaacata aaaaaagact
    46921 tctatctttg caatagaagt ctataattca tggaaaataa atactttatt caacttacat
    46981 aataaaatca aatgcttctt tttcaactcc atctaatttt aaattaaaca tttttaatat
    47041 agttgctgca tgtgctctca ggtctccttc ttctataacc acaccacctt taatatttgg
    47101 tccaaaagct ataaatggag gtctattacc tttagtaggt aaatgaccat gtgtcgcaac
    47161 agcaaacttg taatctttta tatctgaatc ttttataata cttccttcga aatcatttcc
    47221 aaatgaaatt ccttcaagac cttcaattac catttcaaaa tcaccttcaa gaccaaggtt
    47281 agatgcttcc tctttggtaa aaatattctc tatgaataat tcttctttaa attcttcaag
    47341 cagttctctt aattctgtta acctatctaa gttatttact attatttgag ctgatattcc
    47401 agaagaattt acataggcat caaaatcctt aacttctcca ttttcaactt ttataaatcc
    47461 atttgattta agcaagacat ttggatttat aactttatca actctaagat gaccatggtc
    47521 cccaagtatt ataaaatttg tatctttgta tgtacctgca tcctttgtag cctgaataat
    47581 atctcctaac catttatcat tcatttttaa tgctttatct acttcgtcat taaataagcc
    47641 ataattgtgt cgtgtatggt ccaatgtagc taaatgtatt agcattaaat ctggtttata
    47701 ttcctttatt atatctactg aacagtttac tccaaataaa tccatgttgg gttctaattt
    47761 ccaatcgata taatgacaat gtctattgta aataccgtcc attataacct tactggaact
    47821 tcgttcaaaa gtttctcttg ggtcatcttc tctactagga gcccatattt ctgcaatatt
    47881 ataatctata tttggatttg ctcccattac aggccataat acactagagg tagttagatt
    47941 attttctttt gctacatcta taatagtttt tgcttttatg tcctttgagt accagtacca
    48001 gtctttattt tctttatttg ggtcaaattt ttcattatga tatataccat gttttttagg
    48061 atatactcct gtaaccatac tagtatgaca cggatatgtc agagtgggat aaacacaatt
    48121 tatatttttt actatggagc agttttctag tatagattta aagtttggta gattttttac
    48181 aaattccaag tctttttcaa ataaagaatc tactgataat actataacct ttgtcattta
    48241 cattacctct tcatttatat attattgaat acttttaatc aacttacaag tctatataat
    48301 tatttatttg ttttatctat tactgcttgc attgcagaag ttcctttgct tactacatct
    48361 tttggatttg catttaaatc agtaagcccc tttttaatct catccattag cttatcagtt
    48421 gcttccttgt atccatttaa cattggaagt gcaacagcat attgtaattg gtcagttgca
    48481 accttatatt gaggtttttc tttatataat gtttgtaact tttctgagtt tgttgcatct
    48541 tcagttgttg gtaagtatcc tgttgatgaa ctaaactgaa cgattttatc tgtttgtgtc
    48601 atccattcta taaattctgc acttgcttct ttttctttat ctgttccacc ttcaagcata
    48661 actagattag ctccacctgt aggagttgcg tatttttgat tttttggtaa gaatgctgtt
    48721 gatatttcaa acttaccttc tgtttgttgc ataagtcctg ctaaatctgc tgttgatgta
    48781 aatatcatac ctactttacc atttacaaaa tcttgttttg ctacgtccca ggcattataa
    48841 tcttctccag gaggcatttt cattattcca gctttcatca tatcttgcca gaacttaact
    48901 ggtgcttgtc ctgcctcatt attaaatgct acttttttac cattagttat ttctcctcca
    48961 ctttgcatta ccatagcttc atagaaccaa atatctattg gtgtttcaaa accataagta
    49021 tcttctgatt tatttgtcat tttactagca taatccttaa gctcttccca tgattttgga
    49081 cctgaagggt caagacctgc tttagttgcc atatctttat ttatgtataa tattggtgta
    49141 cttctattaa atggcatacc aacaaactta tcctcataat atgaatttgt taaaagacca
    49201 gaaaagaatc tttcttgata tgttttatca aaatatttac tcatatctac taaagcacct
    49261 gctgatgcga atgtacctgt ttgagttatt tctaataatg ttacatctgg ttggtcttta
    49321 gatgttaagg ctgcctgtag ttttgttgca ttttcatagt aatctttctg ttttaacata
    49381 tttacttgta catccttatg ttcactatta aattggtcaa ccattttttg agcagtttct
    49441 ccattagttc cacctaaagg agcccagaaa tctatcttcg taatattgct atcagtcttt
    49501 tctcctttag atgcatttgc atcattagaa tttgaacacc caactaaaga acctaataat
    49561 aatgttattg ctaatcctgt tgctaatttt cttttaagct tcattttcat cctccaaatt
    49621 tagtctttaa ttttttattt tattcctgaa tacataaaag cttcttttac ttttttattc
    49681 gcaaatatat aaacaagaat tattggtaaa attagaatta tatttcctgc cattattaca
    49741 ttccatgcag taattccttc tgaagattta aggagcgcaa ctcctattgg taaagttctt
    49801 attgcatctg tatttgtcat tactaagggc cagaaataat tattccaatg gtatataaaa
    49861 ttaaataata taaatgttat tactgctggt tttgccatag gaaccattat tctaaacatt
    49921 atttttaagt cagaagcatt atctagttta gctgcttcaa taatttcatc tgaaatctgc
    49981 ataaaattct gtctaagcag aaatatccca aatgaagatg tcataaatgg aattataagt
    50041 ggaacataag tatttataaa tccaaactta ctcatcatca tatagactgg tagaaaagtt
    50101 acttgtggtg gaatcataag tcctacaagc aaaagcccaa atagcatttt ttcaccttta
    50161 aatttaatct tagaaaatgc atatgctgct ggaaccataa ctaaaaattg tacaattaaa
    50221 acacttcctg ttacaaatac actgtttagc aaatatctaa aaaatggacc tgaatgccat
    50281 gctgtactat aattttctaa cactatatca tttggtataa tagtgggcgg taattgcatc
    50341 atttcttgtg gatttttaaa ggatgtagat agcatccata taaaagggaa tataaatatt
    50401 gcagataaaa gtaatagaat taatatttct attgattttg atgctatttt ttttatatca
    50461 actttgtctt ttttgatagg ttgtataata tccattgtct cctccttttg gataaacctt
    50521 ataatatcta ctttttcttt attgataatg aactttcttt gataagagtc taaagttagc
    50581 atatgtagca atcataacta tagctaacaa aaacatactc gctgcactcg cttgccctat
    50641 gtcatagtat ataaatccag actcatatat ataataagat aacatgttag ttgaacccac
    50701 tggcccacct tgtgtcatta tacttatctc atcaaatact tgaaaagatg cagttgttgt
    50761 tgttatcata agaaaaaata ttgttggtga taatagtggc aatgtcactt taaagaaatt
    50821 cgttattttg tttgcattat ctaatttaga tgcttcatat atatagtttg gtatggattt
    50881 aagacctgat aacactatta agatattata tccaagagtc ttccatattc ctattagaat
    50941 tagtgacatt aaagctgaac tttcacttga aagccacttt gatgttggta aatgtaatgt
    51001 cgatagtatc cagtttaaaa agccatattg tggctccata atccaaagcc acaatacagc
    51061 tacagatact agtgaaatta catgtggtgt aaagattata ctttgcgtta aattgtgtat
    51121 tatagaattt ttatttagcc aaacagcaag tactatggct agtgatatag atatagtcac
    51181 cataaaaaaa gtataaattg cagtgtttgt tatagtttgt ataaactctg gattctttaa
    51241 aagttctgta taattgttta agcctacatt ttcaaaggtt gaactaagaa gactaccaga
    51301 tttgaagctt agagatatcg tcttaattat tggatagact ataaacaata aagttcctat
    51361 aatagcaggt gttatatata aatatgcttt attaaattgc tttttcataa atatctcctt
    51421 taattttaga atacatactt ttacatactt ttacatcttc tattctttct ccatttttat
    51481 caaaataata taaatctttt tctaatacac ttattcttaa agttcttcca atatcaaata
    51541 tatcattttc tgttttgact cttatctctc tattaagaac agataaacaa tatatagttt
    51601 catttcccaa cacttcttta gttacaactt ttccaaatag actaaataca tcatcatttt
    51661 ttccatctat gtttatactc tctagtgttg ctttttctgg tctgaatcca aatttaatat
    51721 cattttttat atctagtatg ttcatacaag gactccctat aaattgagct acaaataaat
    51781 ttttaggatt ttgatatatc ttctttggag aacctatttg cattatcttt cctttgttca
    51841 ttataactat cttatctgcc attgacattg cctcaacctg gtcatgagtt acataaacaa
    51901 atgtagactt tagtttttga tgtaattgta ttaattctgt tctcatttga tttcttaatt
    51961 tagcatctaa atttgacaat ggttcatcca ttaaaaatac ctttggattt ttaaccatag
    52021 ctctagcaag tgccactctt tgtctttgac ctccagataa gttgcctggt ttcacattta
    52081 aatattctct caatcctact acatcaataa cttctgttat aagtttttct cttttttctt
    52141 tttctacttt tttgttttta agaccaaatt ctatgttttc tctaacagtc atatgtggat
    52201 ataatgcata attttgaaat accatagcta tatccctttt actagcatcc gtttttgtaa
    52261 catcattttc ttcaatcttc aacctacctg aagttatatc ttcaagacct gcaatcattc
    52321 ttaacgtagt agatttacca catccacttg ggcctaccaa tactgtaaaa gaaccatctt
    52381 ctatagtaag atttaaattt tctataactg tatttttttt attataagat tttgttacat
    52441 tttctagtct tatatctgcc atttttatcc tcccaaaata tttaatttaa ttctacgatt
    52501 tacttataga ttaataatac tcttaatttg taaaggatat attaagacaa agtgaatata
    52561 tggtaaactt attaaaataa aggttaaatt ataaacattt tttgttaaat atactgaggt
    52621 taagatgata tacagcttat gttagctata attttctata tttttcatat tcattgtttg
    52681 ctatcacaat gtaattttaa tttatgaaga gtcatataaa actatttatt ttttatataa
    52741 tttgatttga aagtaaaaaa gacctctatg ggggatagag gtctttaagt gggggagatt
    52801 gagtaattta tttttgctat attaagtttt acaattatat tatgtcccaa atttacaagg
    52861 tttaaacata aaaaataaaa attttttaat ttttataaat ttacc
//
LOCUS       DAEPKC010000016        51461 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.016, whole genome shotgun sequence.
ACCESSION   DAEPKC010000016 DAEPKC010000000
VERSION     DAEPKC010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 51461)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51461)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51461
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.016"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            27..101
                     /locus_tag="KR294_001047"
     tRNA            27..101
                     /locus_tag="KR294_001047"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:59..61,aa:Thr,seq:tgt)
     gene            116..200
                     /locus_tag="KR294_001048"
     tRNA            116..200
                     /locus_tag="KR294_001048"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:150..152,aa:Tyr,seq:gta)
     gene            210..293
                     /locus_tag="KR294_001049"
     tRNA            210..293
                     /locus_tag="KR294_001049"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:244..246,aa:Leu,seq:tag)
     gene            317..391
                     /locus_tag="KR294_001050"
     tRNA            317..391
                     /locus_tag="KR294_001050"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:349..351,aa:Gly,seq:gcc)
     gene            416..492
                     /locus_tag="KR294_001051"
     tRNA            416..492
                     /locus_tag="KR294_001051"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:450..452,aa:Arg,seq:tct)
     gene            502..577
                     /locus_tag="KR294_001052"
     tRNA            502..577
                     /locus_tag="KR294_001052"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:535..537,aa:Gln,seq:ttg)
     gene            586..661
                     /locus_tag="KR294_001053"
     tRNA            586..661
                     /locus_tag="KR294_001053"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:619..621,aa:Lys,seq:ttt)
     gene            664..752
                     /locus_tag="KR294_001054"
     tRNA            664..752
                     /locus_tag="KR294_001054"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:698..700,aa:Ser,seq:tga)
     gene            756..831
                     /locus_tag="KR294_001055"
     tRNA            756..831
                     /locus_tag="KR294_001055"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:789..791,aa:Phe,seq:gaa)
     gene            838..911
                     /locus_tag="KR294_001056"
     tRNA            838..911
                     /locus_tag="KR294_001056"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:872..874,aa:Met,seq:cat)
     gene            926..1002
                     /locus_tag="KR294_001057"
     tRNA            926..1002
                     /locus_tag="KR294_001057"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:960..962,aa:Ile,seq:cat)
     gene            1020..1096
                     /locus_tag="KR294_001058"
     tRNA            1020..1096
                     /locus_tag="KR294_001058"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1054..1056,aa:His,seq:gtg)
     gene            1105..1180
                     /locus_tag="KR294_001059"
     tRNA            1105..1180
                     /locus_tag="KR294_001059"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1138..1140,aa:Lys,seq:ttt)
     gene            1188..1261
                     /locus_tag="KR294_001060"
     tRNA            1188..1261
                     /locus_tag="KR294_001060"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1220..1222,aa:Cys,seq:gca)
     gene            1269..1345
                     /locus_tag="KR294_001061"
     tRNA            1269..1345
                     /locus_tag="KR294_001061"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1303..1305,aa:Arg,seq:acg)
     gene            1358..1433
                     /locus_tag="KR294_001062"
     tRNA            1358..1433
                     /locus_tag="KR294_001062"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1391..1393,aa:Val,seq:tac)
     gene            1509..1922
                     /locus_tag="KR294_001063"
     CDS             1509..1922
                     /locus_tag="KR294_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239151.1"
                     /translation="MYIVIGNEIVDSEELKIIIDKNSEFKVEKDLSKSTKREDVIAYQ
                     LSIDLNYLDSLINEQCNLASLSDEEKFDEYMTLSDELALDLEELMPKYTIINARAYKL
                     DEVDGIVKIILAVAYADLGHLKLSDVVKRLSRQVD"
     gene            2231..5662
                     /locus_tag="KR294_001064"
     CDS             2231..5662
                     /locus_tag="KR294_001064"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HBH0239152.1"
                     /translation="MLKKFNKILVANRGEIAIRIFRACSELGIKSVGIYSKEDKYGLF
                     RTKADESYLIGEGKGPIDAYLDMDGIIDLAKRKKVDAIHPGYGFLAENAEFARKCEEN
                     GITFIGPSSKVMNMMGDKINSKKIAKEVNVQTIPGVEKAIRSTEEAKEVANKIGYPVM
                     IKASNGGGGRGMRIVHREEDLELEYETACSESRKAFGEDIIFIEKYIADPKHIEVQIL
                     GDNYGNIVHLYERDCSVQRRHQKIIEYAPAFSLDDKVRKEICEDAVKLSKHVGYSNAG
                     TLEFLVDANGGHYFIEMNTRVQVEHTVTEMVTGIDIVQSQILIAQGYSLDSEEINIKS
                     QDDVEIRGYSIQCRITTEDPKNKFMPDTGKIQVYRTGSGFGIRLDGGNGFTGANISPH
                     YDSLLVKTISWDRTFQGAINKTIRSIKELRVRGVKTNVGFLVNVLNNPIFSNGKCSTK
                     FIDENPDLFEITESKDRGTKLLQFIGDVIVNDNACKEKPLFDALHDPRMDKDGSKSEG
                     SKILFDKLGKSAYIEKIKNDKKLLLTDTTMRDAHQSLLATRIRTYDLLKAAKPTEKYQ
                     KDLFSLEMWGGATYDVAYRFLKESPWRRLQKLREEIPSIMFQMLLRASNGVGYKNYPD
                     NVIEEFTKESARQGIDVFRIFDSLNWVENMKPSINTALETGKIVEATMCYTGDILDKT
                     KTKYNLEYYIKMAQELESLGADIIAIKDMSGLLKPYSAYTLVKELKKNVKAPIHLHTH
                     DTSGNGVATCLMASEAGVDIIDAALESMAGLTSQPSLNAIVEALKNTERDTGIDLFGY
                     DELGKYYKDLRKVYNKFESDLTNSCAEIYNFEIPGGQYTNLKPQADSLGLVNRFDEVK
                     EKYKEANEVVGDIIKVTPSSKVVGDLAIFMTKNKLDKDNIIEEGKNLSFPDSVVDYCK
                     GMIGQPEGGIPKDLQEVVLKGEEAITVRPGSLLPAEDFDEIAKYLNEKYDINANIRNV
                     ISYALYPKVYEDYIKHLQHYNDISKLESDVFFYGLNKNEECEVEIEEGKVLTIRLVEI
                     GEVKENGFRTIGFELNGMVREVEIKDKNFSGKINNVEKADMNDPLQIGASIPGKVIKI
                     MVKEEDEVKANQPLIVIEAMKMETIIVAKTDGVIKSIKVKEDDMVEDKQLLMIMK"
     gene            5904..7832
                     /locus_tag="KR294_001065"
     CDS             5904..7832
                     /locus_tag="KR294_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HBH0239153.1"
                     /translation="MKVYDSKMLRNVAVLGHSGCGKTNLIETIAYTANTNKIPKLTDK
                     VNMTYSMGLIPIEYNDYKFNLLDTPGYFDFSGDVVSSLRASDAAIIVIDATAPIQVGT
                     EKSLELTESIPKIMFINKIDNEKARYKDAIAMLREKYNNKIVPMISPIYKDKNFVKLH
                     NVFENIDDLEGEFKEQAMSVKEALMELIAETDDQILDKYFNGEELTTEEIQKGIIIGI
                     QRGDIIPVICGSTINNIGTKEILDTISSYLEPIFTEESKPFRGLVFKTMVDPFVGKMS
                     YIKITEGVLSKDKDVFNINKNVKEKIANIYTLRNSELVEIEKAKAGDIVVITKVNSLK
                     TGDTISADKDAEALEKIDFPKPQIYYAVTPKNKGDEEKVASVLNKLVEEDPTLHWYRN
                     TETKQALLGGQGELHIKTIKNKMKDKFGVDVELNDLKVPYRETIKGTADVQGKHKKQS
                     GGHGQYGDVKIRFERCESDFEFTEEIFGGSVPKQYIPAVEKGLKDSMQKGILAGYPVT
                     NIKATLYDGSYHDVDSSEMAFKMAASAAFKKGMEEAHPILLEPIMKLKITVPEEYMGD
                     VMGDINKRRGKIFGMEPDDKGKQIIFAEAPQAETFKYAIDLRAMTQGRGYFEMELERY
                     GEVPSQFAEKIIGLATAK"
     gene            8285..8749
                     /locus_tag="KR294_001066"
     CDS             8285..8749
                     /locus_tag="KR294_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HBH0239154.1"
                     /translation="MATMTDIIEKFIKDLMEEDNSIQIQRNELANLFSCAPSQINYVL
                     TTRFTIDRGYYIESKKGGGGYVQIEKIRKSKDGHIRELLNEKIGSQISYKKAKELLEG
                     LKESDLINERELKLILYAIDDKSLCMPIYELKEKVRSNILKNIIIGLFSIEE"
     gene            8756..9250
                     /locus_tag="KR294_001067"
     CDS             8756..9250
                     /locus_tag="KR294_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UvrB/UvrC motif-containing protein"
                     /protein_id="HBH0239155.1"
                     /translation="MLCQKCNKNKASVYYNKIVNGEKTEMYLCSECAKENTEMNFNLD
                     MPFSMMDIFSNLGFQPKKELEEKLVCPKCNTTYSEFKNNGRFGCSECYNAFSSQVNPM
                     LQNIHGHIEHTGKAPKKSFYKISVENEIKELKEDLDRAIKNEEYELAAQFRDKIKYLK
                     GSID"
     gene            9266..10291
                     /locus_tag="KR294_001068"
     CDS             9266..10291
                     /locus_tag="KR294_001068"
                     /EC_number="2.7.14.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein arginine kinase"
                     /protein_id="HBH0239156.1"
                     /translation="MKENIVMKSRVRLARNLNNYPFPNKLDKECAMEIIEKVKNAFIN
                     SNLEQKEEFDFYKIEDLDQSKKMLMVEEHIISPDLAENDKSAVIVKKDKTISIMINEE
                     DHIRIQTICDDLNLEYAYSVANEIDDLLESSLEYAFNTKLGYLTSCPTNTGTGMRASV
                     MMHLPALSQLGYMDELYKISSQIGIAIRGIYGERTEALGNIYQISNQLTLGRTESNII
                     ENVSGLTKDAISKEIKAREILQKKLGIKLEDKIFRSIGTLENSRVMSSAEAMSHLSNI
                     KMGIEMNYIDKLDLRAIEQLMIGIQPAHQSIMYKSDDVENRDINRATYIRETLEKLRG
                     GMNCELQ"
     gene            10278..12725
                     /locus_tag="KR294_001069"
     CDS             10278..12725
                     /locus_tag="KR294_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HBH0239157.1"
                     /translation="MNFNRFTQRAKKAIDLAFESAKSLGHNIVGSEHILLGLLREEEG
                     IAAKVLSKVGFTEAYLEGKIVDMEGKGEEISEDIVLSPRSKQILELSGMFANKLKTNY
                     IGTEHILLAIIQEGEGIANKILNYAGVNDRTLAQLTIDMMGISDKNQYKAENSYTGNQ
                     NQAESKVLDKYGRNLTLYAKQNKIDPVIGREKEIQRVIQILSRRTKNNPVLIGDPGVG
                     KTAIAEGLATNIALGNVPETLKNKTLYSLEMGSLLAGAKYRGEFEERIKEVVDEVVKN
                     GNIILFIDEMHTIIGAGSTGEGSIDASNILKPALARGEIQVIGATTIDEYRKHVEKDS
                     ALERRFQPVMVDEPTKEDSIKILEGLRDKYEAHHKVKITDDAIKAAVELSTRYISDRY
                     LPDKAIDLIDEAASKVRLKENTPPSEIKKLELEIENIDKEKEEAVRCQDFEKAAKIRD
                     EQGLLKKQLEDVRERWNKSSKHSDLVDGEVIAEVVGLWTGIPVNKILEEEADRLLRLE
                     EILHNRVIGQEQAVKSISKAIRRSRAGLKDPNRPIGSFLFLGPTGVGKTELSKALAEV
                     QFGDENQIIRIDMSEYMEKHAVSRMIGSPPGYVGHDEGGQLTEKVRRNPYSVILFDEI
                     EKAHPDVFNILLQILDDGRLTDSKGRTVDFKNTIVIMTSNVGASTIGRQKTLGFSIAK
                     GDEEEKSQYEKMKENIMGELKQRFRPEFLNRIDDIIVFHSLNENHISKIVLLMAAKLQ
                     ERLKEMDIKLEMSDEAVKLISKSGFDLEYGARPLKRALQKELEDELSEAILKGNVKKG
                     SNVVAKVKDEKIVFETK"
     gene            12905..14278
                     /gene="radA"
                     /locus_tag="KR294_001070"
     CDS             12905..14278
                     /gene="radA"
                     /locus_tag="KR294_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HBH0239158.1"
                     /translation="MAKIKTKYVCQSCGYETAKWLGKCPECTKWNTFVEEIDQKSTKK
                     EVFIIDKSSSKPVSINSIESKEEERFTTDINELDRVLGGGIVKGSLVLVGGDPGIGKS
                     TLLIQVSSNVANLGKTVLYITGEESESQIKMRAKRLGINSENLYIFAENNLSIIESYL
                     ESVNPELIILDSIQTVFSPEISSAPGTVSQIKEGTSKFMKISKKMGISTFIVGHVTKE
                     GSLAGPKLLEHMVDTVLYFEGERYNTYRLVRAVKNRFGSTNELGVFEMRDLGLVELDN
                     PSKILISEKPKDVAGSVIISTVEGTRPMLLELQALVSPTSFGIPKRTSTGVDYNRVGM
                     LLAVLEKRVGLQIQNQDVYINIVGGIKINEPSIDLGIAISVASSFRNIPIDEDIAVTG
                     EVGLTGEVRAVSFIEKRIAECKKLGFKKIVVPRSNYDVVKETKGIEIWPVDNLRQAIN
                     IVLGRNQ"
     gene            14281..15351
                     /gene="disA"
                     /locus_tag="KR294_001071"
     CDS             14281..15351
                     /gene="disA"
                     /locus_tag="KR294_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA integrity scanning protein DisA"
                     /protein_id="HBH0239159.1"
                     /translation="MENFLDNKNMLYALKMISPGTPLRLGLNNVLRAKTGGLIVIATN
                     EDVMKIVDGGFAINAEYSPSYLYELAKMDGAIVLSGDVKKILFANAQLIPDYFIETSE
                     TGTRHRTAERVAKQTGAIVIGISQRRNVITVYRGNEKYVVEDISKIFTKANQAIQTLE
                     KYKTVLDQAVTNLNALEFNDLVTIYDVALVMQKMEMVMRVTSIIEKYVIELGDEGTLV
                     SMQLEELMGTTRIDQKLIFKDYNKENTEIKELMKKVKNLNSEELIELVNMAKLLGYSG
                     FSESMDMPIKTRGYRILSKIHRLPTAIIENLVNYFENFQQILDASIEELDEVEGIGEI
                     RATYIKNGLIKMKQLVLLDRHI"
     gene            15440..16534
                     /locus_tag="KR294_001072"
     CDS             15440..16534
                     /locus_tag="KR294_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HBH0239160.1"
                     /translation="MIRKVTRILFILLGFTIGITTYLTLMKDFEILTFGKETYGYIAA
                     VVAGIIIAILGYLIEPWVVNKVKEIAKIVDKELSKYPQTDILLGSMGLIVGFVIAYLL
                     SGLVNRIPIVGGILSLLLYLFLGYLGMKVALKSKNDLFNIGKLGRLANPIKDKDKDKE
                     NKKEVKAIPPKVLDTSVIIDGRIADICKTGFIEGKLIIPAFVLEELRHIADSSDDLKR
                     VRGRRGLDILNIIQKELNIEVEISERDFDDIAEVDSKLLKLAQVLNGKVVTNDYNLNK
                     VAQFQGVEVLNINELANAIKPVAIPGEDMVVQVVKEGKEAQQGVAYLDDGTMIVVDGG
                     RKYMNETIKVLVTSVLQTPAGRMIFAKPKN"
     gene            16663..18840
                     /locus_tag="KR294_001073"
     CDS             16663..18840
                     /locus_tag="KR294_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239161.1"
                     /translation="MRKKIISFLATFIIILTSASQYSFADDISTRGKVIFIDMNRTSM
                     SNMLRIKSLREELDNRGYIGLMNIRGDKGSDDRRSYASMGAGGRANVANEEDINFESS
                     SKDRNIVFESATGKSAKGINNLTINKSINENLNFGEYGSVLGSLGQSLSDNGLKASVL
                     GNSDIIENGQLIKNRNLCLTAMDEYGRIPNGNVDTINKKDLSMPYGISTDYDKLIVET
                     KETYKNNDVIFVELGDTYRLDLYKPNLNEKTYESMKDNIEKNIDIYLKNIFSMVEEND
                     TIYIASAFPSDLDYKNKRRLSPIIKLNGEGKGILSSSTTRREGIVTNLDVGVEILDNF
                     NIKNQNMVGRKYELINRDDNKEFLMDEYQKIVSISSIRSTILNGFVSIVFLSWIVAMI
                     AILFRKHISKNYKETTFFILKELLKIGIVMPLSFMITPIMNFKTPLAISLGIIIITLT
                     IYLISKVLIKNDLKNMLFFTGLTIVIMVIDAGFGSYLMKSNVMSYDCIIGARYYGVGN
                     EYQGVAIGSAIFTFAILLTYKNIPKWYIIVFSLVILITSASPIMGANVGSAISECVAF
                     LLFILLIYNVKIDFKKIVLLGIAVVFVLGVFVAIDMILGSNSHLGMFVKEIYFNGPGE
                     IIQTFSRKIEMNLKLAQTSAWVNILLTGIGVILVLMINQIRYFKQLMDEYPIVFKGFI
                     ASIAGCLVTLLVNDSGIVSSATAFIYVIVPMITLSINLTALKE"
     gene            complement(19026..19871)
                     /locus_tag="KR294_001074"
     CDS             complement(19026..19871)
                     /locus_tag="KR294_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH0239162.1"
                     /translation="MNRNNFSHEIIEPIDNLDVNFKLFDDSGSYVANHWHNSLEIIYI
                     TSGDLQINMEGYTYNLKANECMFINSGIIHSTRCIYQNTSILLQVPLSFLNKYIPDFK
                     NCYFDFKVNANDNNYKKNSSKVKLILENMREIKLSSPPAANLLFTSLLFELLFELYTN
                     FKISVGNKNMKKTVLDLSKFEPVLEYTKINYKMPISINKIAKVAHLQPEYFCRKFKQY
                     MGQTYLEYLNDVRISHIYKDLINTNDTLCSILEAHGFTNTKLFYRIFKEKFKCTPKHI
                     RKKST"
     gene            20088..21254
                     /locus_tag="KR294_001075"
     CDS             20088..21254
                     /locus_tag="KR294_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulase family glycosylhydrolase"
                     /protein_id="HBH0239163.1"
                     /translation="MYIKGVNLGGWLVLEKWMTSSLFEGTEAEDEYYLPRQLSREAYE
                     SRIKTHRSEYITERDFATIKSMGFNSVRIPVPYFIFGDCEPFIGCVKELDKAFAWADK
                     YGLSILIDLHTVPGSQNGFDNGGISGICSWSQNPEYVAFTLNVLERLAKRYGMRHELY
                     GIQILNEPITERMWNIMNVPNRFKAVDKEMARGSKPNSLEFLRDFYIKAYRVMRPYMR
                     EENVIVFHDAFELKAWKDFMREEEFKNVVLDTHQYLMLAEADGCEQSIDSYLKYIREN
                     YAKDILQMQKYFPVICGEWSLFNSYVCGIDTNGGQSPLNGIESNIDKLSKDDKRELYR
                     KIAKAQLDAWRNGSGHYYWNYKLLLDTVNEEGWIGWDSWDLGKCVAQEWYPIEY"
     gene            21276..22922
                     /locus_tag="KR294_001076"
     CDS             21276..22922
                     /locus_tag="KR294_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HBH0239164.1"
                     /translation="MIKNPILPGFNPDPCICRKGDDYYLVVSSFEWFPGIPVYHSKDL
                     KNWELYTHILTDETKIDLKKLPSSKGIWAPCLTYCEEEDLFYIVYGIMNSMNARYFDV
                     DNYLITSKDIKGEWSEPVYLHSSGFDASIFHDDDGKKWIASLDWETREGYEKPGVICL
                     VEYCTKKKEIVGYPKRIWSGGTDRGCIEAPHITKRGDYYYIMCAEGGTGYGHSVTMGR
                     AKNIWGPYEKDSMNPIVTSIPGDFYERHDPDHLKPKYYNPESKLQKSGHGSYIETTSG
                     EVYLVHLTSRPFVPELRCTLGRETAIQKMKWTKDNWLRMEDESNLAKEYVSESKLEEH
                     LVSSIPSFDDFDSNELGLQYYAPRISPLSFADVKSRPGYVRIRGQESRTSLNKVSILA
                     RKLTSVYARITTKMEFYPEVHQHSAGLIMYYDNMNYINLRKYYSETLGQSALSIIHLE
                     NGEKTEFLNTRIPIKDIPIYLRLYIQGRKSYFEWSYDEKNYQRIGKVFDTTKFSDEYC
                     KYGEFTGTFIGLTCADRVKHKHYADFDFFEYIVDESKDVD"
     gene            23019..24392
                     /locus_tag="KR294_001077"
     CDS             23019..24392
                     /locus_tag="KR294_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH0239165.1"
                     /translation="MNTEVNVKATTIRYEKISFFERISYGCGDLGCNIIYSAMSAFLL
                     FYYTNYADVSAAAVGSIMLVSRILDGFSDLTMGIIVDRTKSKYGKARPWILRMAIPFA
                     IAAVLLFSVPSNLGITSKLIYIFITYNLVSTVIYTAINVPYATLNSLITQNQYERGVL
                     SIFRMILATCGTLLINGLTLPLVEYFGNNLSAWTKTFFVFGIASIMVFFITFTGTKER
                     VKAVKQDRNEVIPFKIGIKSLFRNKYWIQITLCLVCIFIVFAINGGSSVYYAKFILGD
                     EKLFGPINMVSNISQIIAMFMVAPFIKKFGKRNVLIVGSIILISSNVMFIIVGQNHIG
                     VIFASAIKGIGSAGIASTMFAIVSDTIEYGEWKTGYRTEGLINSASSFGFKVGNGLGS
                     AILGAVLSIGGYVGTSATQSDLAIVSIKVCFIYLPIFITILQIIIMSFYKLDKEYSTI
                     LNELNTK"
     gene            24837..25790
                     /locus_tag="KR294_001078"
     CDS             24837..25790
                     /locus_tag="KR294_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HBH0239166.1"
                     /translation="MKKIGDLRLMMKCCSLYYEDNLNQQEIANQLGISRPTISRILKE
                     AFEQGIVKIQIVDVLKNDYQKIERSLERKYKLKEVIVVDDKQDALTQKQELARAVSEY
                     LTRVVKENDIIGVSIGTTLKEIPRYVEKSNCKNVTFIPLLGGIGDNEIDIHANQIAVS
                     LARAFGGDFKLLHAPAVMSDLSTKEKLCKDEKIKEVLDLIDKTTIAIVGIGNPMSLNS
                     TIMASGYMNEADIEDLKKYNSIGAICLQAFDKEGKTSILEFNQRVLGVKLEDLKKIKR
                     TIGVASGDEKIEAIKASLKAKFINSLAINHSLALKLLEDCD"
     gene            25828..26790
                     /locus_tag="KR294_001079"
     CDS             25828..26790
                     /locus_tag="KR294_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HBH0239167.1"
                     /translation="MSISKETLLEMYKRMNQARKFEEKVSWFFARGMVHGTTHLSVGQ
                     EASSVAAVMALEKGDLVSLTHRGHSQFIGMGIDLNKMMAELMGKETGFCKGKGGSMHI
                     ADIESGNLGANGVVGGGLTIAPGAALTQQYKKTGKIVLCSFGDGASNEGTFHEGINLS
                     SIWKLPIIFYCENNLYGMSTSIKRHMNIESIATRAASYGIEGISIDGYNPIEVYETVQ
                     KAAEKCRRGEGPVLIESRTYRWLGHSKSDANVYRTKEEIESWKAKDPIEFLKNYLIEN
                     NLSNEDELDKIQEFAKQSIEDAVEFAQNSPNPKIESLLEDVYAD"
     gene            26815..27801
                     /locus_tag="KR294_001080"
     CDS             26815..27801
                     /locus_tag="KR294_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HBH0239168.1"
                     /translation="MSTRELTYAQAIKEAMSEEMRRDENVIFMGEDIGIYGGAFGVSV
                     GMIDEFGPERVRDTPISEAAIAGAAAGAAATGLRPIMEVMFMDFVTISMDAIVNQAAK
                     MRYMFGGKAQVPMVVRCPGGSGTGSAEQHSQSLEAWFCHVPGVKVVAPSTPADAKGLL
                     KAAIRDNNPVIFVENKLLYRKKGFVPEDDYVIEIGKADIKREGTDVTVITYGRMLQSV
                     EEAAETLSKENINVEIIDLRTLYPLDKETIVKSVCKTGRVLICHEAAKTGGLGGEISA
                     LITESESFDYLDAPVKRICGKDVPIPYNPELEKAVVPRVDEIEEAIKSLIVR"
     gene            27814..28860
                     /locus_tag="KR294_001081"
     CDS             27814..28860
                     /locus_tag="KR294_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxo acid dehydrogenase subunit E2"
                     /protein_id="HBH0239169.1"
                     /translation="MVANKIKATPAARSQARKDNIKLDRLIGSGENGRIHLVDVLNYL
                     KDNKANTTPLARRIAEDLNIDLETIVGTGYNGKIRKCDVEKLTGKETIVSTNTSKSSE
                     KKELKIENENSRMFNTVEGIFEKPNPMRATVAKRMSESYFSAPVFTFNIEVDATELKV
                     LRAKLIDTVKESTGVKLTMTDLIVMAVSKILPNHQALNSAWTDEGIFRYKDVNIAIAV
                     GLDEGLYVPVVKNANKKSLKEIAKESKELAEKVKTGKLMPADQEGNTFTISNVGMYGI
                     TTFTPIINMPSSAILGVGATQDKFVPVNGEAKIKPIMNLSLTSDHRVIDGTVAAKFLK
                     DLKELLENPLSMLV"
     gene            29027..30757
                     /gene="lpdA"
                     /locus_tag="KR294_001082"
     CDS             29027..30757
                     /gene="lpdA"
                     /locus_tag="KR294_001082"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HBH0239170.1"
                     /translation="MSVEVIMPKAGVAMEEGTIVSWLKQEGEEVKIGEPILEITTDKV
                     NMEIESEGEGTLAVIIHKEEGEVLPVFTVIGVIAEKGENQEEVKAKYLSGNVSKEDIV
                     EENQNIEFKEEKINKKECNHDYDVVVIGGGPGGYLSALKAALLGGRVALVEENILGGT
                     CLNRGCIPTKTYIKTAEILEEIDQLSKRGVKVTVDKEQDIKKAIKYKNRVVKKLTAGV
                     GGLLKSRDVDVFNLKASVKEEHKVILSDGKVLDTENIIIATGSKVRILPIKGIESNLI
                     ITSTEALDLETVPEELVIIGGGVIGCEFAEIFNSRGSKVTIVEMEDRVIPRMDKELSE
                     SLKYSLSKKGINVLTKKKVSEFKEEGNNILVCIEGEEPIKADLCLYAIGREANLSGIE
                     DLDIKIDKGSIVVNSKMETSIPSIYAVGDVTGGVMLAHAAFKMGEVAASNALGVNKEV
                     DLGALPSCVYTIPEVASVGITEEDARKKYNVKVGKFNFAGNGRALASGQEQGYVKVVA
                     DAKYGEILGIHMFGCGVAELINHAASFKALEIPTDEASELIFGHPCTSEALMEALADV
                     NGECLHLPKK"
     gene            31175..34123
                     /locus_tag="KR294_001083"
     CDS             31175..34123
                     /locus_tag="KR294_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH0239171.1"
                     /translation="MRQRIKNLIENEDKKNPLTDEAISSRLNIRREDVTFLRNELKIE
                     DSRQRRKVVLIKAIKDILKEEKTINKNDITRRLNSIGFTVSRFTVIQYLKEIQDSGDL
                     KLDKESDDKKEEIINNRENKDIAFDKLIGSSGSLSTIIKLAKAAILYPPHGLHTIIMG
                     PTGVGKSELAECMYKFAVESSRFPKNAPFIVFNAADYSENPQLLLSQLFGHVKGAFTG
                     ADENKEGLVSKADGGILFIDEIHRLPHEGQEILFQLIDKGMVRKLGETRLTHKIDVMI
                     ISATSEPIDSHLLNTFKRRIPVTIEIPELVARPLNERFDIINNFFLIEAQRMGANIHI
                     KSDVLKALMLYDCIGNVGQLRSDIQVACARGLLNQLTNKLKEVNISISDVPGYVKQGL
                     IKIRNCRGKIENYVDGDLIIDSNLQGEIEKKNEDIYTFPDEIYKLTERRHIDLLEQGL
                     DFDVINRIIGGELESCIQKYIKQVKKVSISNNLPDISPIVGKYIVELTYEVIKIASQY
                     LSSLEPNLHLCLAVHLKAAFERLKEGKVISNAHLKEIIGNYPVEYSVAEKVAQYLKER
                     YNINLPKEEIGIIAIYFKMSSRRDMSEQKKIGVLLMAHGRVASSVCEVTNKLLGINHA
                     RYLDMPFEKKPEEMIEEATTIIKDIDEGRGVIILVDMGSLSYFGDIISGKTGINIRTI
                     SRFDTLLSIEVIRRAVLPDLTIDEIVDEVKGIEPQVKEKVSKCNNTKVDFRKPIILTL
                     CITGLGGACKIKKILEENIKSITEKVDIEPIGMIEYPSLDLEIKQISNDKNVIAIVGT
                     IDPQIANIPFFSLVDINDKAKLNQINNLIDTNQIGETNKKYELSDLIHKEDIFVDLQV
                     KSKEEVLKYMSKKLREKGYVTKNFYKKVVERDNLFPTELSDEIAIPHTDGIDVIRPAI
                     SIAILKKPIVWSKSKVKIILLLAVDQKCFNPLSTLLSFIETDEFKKIKNIKDRDFIRE
                     MILDGVNENN"
     gene            34101..34565
                     /locus_tag="KR294_001084"
     CDS             34101..34565
                     /locus_tag="KR294_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH0239172.1"
                     /translation="MESMKIISSNLIFKNIEVSNNEDALKFLGQRLFDEQYVKESYIQ
                     AVVAREKKYATGLPTEIYGVAIPHTDIVHVNEPGIAIGILNKPVKFIMMGTDDTEIDV
                     KVVFMLAVKEPQEQLQLLEKLMTIFQDKNILNNIVDLSEESVSDLLNSKLKN"
     gene            34678..34980
                     /locus_tag="KR294_001085"
     CDS             34678..34980
                     /locus_tag="KR294_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH0239173.1"
                     /translation="MGVTNVAKKILVACGTGVCTSTIAINKLKKALQDIGKLDMVNIT
                     QCKVVEVASKAPDYDLIICTTQVSSSIKTPVINGLPFLTGVGMDKLINDVLEELEL"
     gene            35042..36406
                     /locus_tag="KR294_001086"
     CDS             35042..36406
                     /locus_tag="KR294_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425524.1"
                     /note="with GatAB forms a phosphoenolpyruvate-dependent
                     sugar phosphotransferase transporter for galactitol;
                     subunit IIC forms the translocation channel and contains
                     the substrate binding site; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HBH0239174.1"
                     /translation="MEGLYMEILNFIVGLGAQVMMPIIICIFGLILGTKLGKSLRAGL
                     TVGVGFIGLNTIIALLTDNLGPATQQMVKNLGLSLSIIDVGWPAASAIAFASTVGALI
                     IPIGLVVNIVMLITNTTQTVDVDIWDYWHFAFTGALVAGATQSVMWGVFASVANMVIV
                     LVMADLTAPGIEEYLGMPGISLPHGFTQAFVPIAIVVNKLLDLIPGINKIEINADTLQ
                     KKFGLFGEPLIMGSVIGVIIGIAAKYDIKGILQLGVTMGAVLILIPKMAALLMEGLLP
                     VSEAAQEFIEKRFKNRGKIYIGLDSAVGIGHPVTLSVALVLVPLTILIAAILPGNKVL
                     PFADLAVIPFALVLIVPITKGNVFRTLIIGIIIITSGLLIATNLAPLFTQMALNASFK
                     MPEGATMISSICDGANPLSWVFVKVMNYKVIGGVVFGVIALGMAIYNRNRIINENKKL
                     SIEE"
     gene            36441..36914
                     /locus_tag="KR294_001087"
     CDS             36441..36914
                     /locus_tag="KR294_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239175.1"
                     /translation="MKKYKYDSKRYLLSVTIPGFFMILILIYALFNNYTNFNLNIYSL
                     LIIVCTYGIFNTFISSSNPKKIIIDSKCIHFTSFMTTHKYEIKDIEKIRIREFYNKKI
                     YVKINDGNLFKGRYWIRTNMFNNSIALYSYFIELEECLYPDSLKFRNKKFENKNI"
     gene            37086..37736
                     /locus_tag="KR294_001088"
     CDS             37086..37736
                     /locus_tag="KR294_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HBH0239176.1"
                     /translation="MLLEKLRKEVLQASLDLLNYNLVTLTGGNVSGRDEQTGYIAITP
                     SGMDYRNLTPSDIVIVDVDGNIIDGKWKASVDLSDHLYIYKHREDINSIIHTHSTYSS
                     CFAILNEPIECASTTLANEVGGSVPVAKFSPPTSKKMGKCVIEAIGDKRACLLANHGV
                     IAVGPSVGHALTAAVMLEDSAKVYYLAKSIGTPVLLPDEEIQRARDVFFNVYGQDK"
     gene            37910..38842
                     /locus_tag="KR294_001089"
     CDS             37910..38842
                     /locus_tag="KR294_001089"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HBH0239177.1"
                     /translation="MYYLLNKSTNPYFNLALEEYLFLNDKYNDDIIIIWRNEESIFIG
                     KNQNPYQEVYHDVIEKGEIPILRRISGGGTVYHDLGNINMSFIQKDRQLHEIDFLEHT
                     KFMQKMLSTLGLDVSITERKDLFLNGKKISGSAQSIKRKNSLYHGTLLYDSDLNKLTK
                     YLNSNKATESNATKSVSSKVTNIKFLLEKDINYFLDYCVEYLKSNIKNIKELELDEED
                     IKSVYNIGEDKYKKIEWTYGKTPKFQVVLPFNNESKINIHVNRWKVSKFFISYDDNVI
                     NMDKLLDLNFFKEEIKESILENYPHYIDLINLIF"
     gene            39116..39829
                     /gene="ispD"
                     /locus_tag="KR294_001090"
     CDS             39116..39829
                     /gene="ispD"
                     /locus_tag="KR294_001090"
                     /EC_number="2.7.7.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HBH0239178.1"
                     /translation="MYSVIIVAAGSGRRMNLDINKQFIKLREKEIIAHTIQVFYENIN
                     IDEIVVCIKKEEEDFFKENIINKYNFKNIKIAYGGKERQDSIYNGLKKLDENCDIVLI
                     HDGARPFVDHRIINESIKVAKEKKAVVVGVPVSDTIKIVSDGTVQETPERNLLWAAQT
                     PQTFEYNLIIDAYEQAYKNNYYGTDDSMLVENIGQSVTMVMGSYENIKITSPEDLNIA
                     EQILNMEKRDEVNSRRRII"
     gene            39826..40311
                     /locus_tag="KR294_001091"
     CDS             39826..40311
                     /locus_tag="KR294_001091"
                     /EC_number="4.6.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 2,4-cyclodiphosphate
                     synthase"
                     /protein_id="HBH0239179.1"
                     /translation="MRIGLGYDVHKLTEDRKLIIGGVEIPHDKGLLGHSDADVLIHAI
                     MDSILGALALGDIGKHFPDTDEEYKGADSMKLLEHVYNLITSKGYKIGNIDSTIIAQS
                     PKMAPYIESMRSNISKVLNTDIDNINIKATTEEGLGFTGAKQGIASQSICLLLLTSQN
                     N"
     misc_binding    40406..40614
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            40678..42393
                     /locus_tag="KR294_001092"
     CDS             40678..42393
                     /locus_tag="KR294_001092"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HBH0239180.1"
                     /translation="MKMSKMFMPTLKEIPADAEITSHQLMVRSGMIKKMTSGVYNQLP
                     MGLRVFKKIEQIIREELNKKDCQEILCAALLPSELWKESGRWTAMGEEMFRLKDRTER
                     EYCLGPTHEEAFTDIIRQEITSYKQLPLNLYQIQVKYRDERRPRFGVMRTKTFTMKDA
                     YSFDVDDKGLDKSYQDMFDAYVSIFDRCGLENSPVQADSGAIGGSTSAEFMVKSEVGE
                     DEVVFCSGCDYAANVERAESCNLASQKEEMKELEEVHTPGAATIKELEEFLKTSPDKF
                     AKTLVYEADGKTVVVVVRGDREVNEIKVSNAIGSVIEFALATDDVVRKVTNAEVGFAG
                     PIGINADYVFIDKEIVEQRNIVVGANKTEYHIKNANYGRDFEGIVGDFRNVQEGDKCI
                     VCGKPLEIARGVEVGHIFKLGTKYSESMNANFIDKDGKSKPIVMGCYGIGVERTAAAI
                     IEQHNDEKGIIWPLSVAPYHVVIVPANMKNEEQISIAENIYNDLQAMGVEVLLDDRDE
                     RIGVKFNDSELIGIPMRITVGKNINEGKVEFKLRHKEDKEIIDIEEINEKVKAEFIRN
                     NVRLG"
     gene            42515..43960
                     /locus_tag="KR294_001093"
     CDS             42515..43960
                     /locus_tag="KR294_001093"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HBH0239181.1"
                     /translation="MAKNEKQFVEEITKMEDDFPQWYTDVITKTDLVDYAPVKGFMVV
                     KPYGYALWEKMQEFMDKKFKETGHKNCYFPLLIPESLLNKEAEHVEGFAPEVAWVTHG
                     GNKKLEERLCVRPTSETIICTMYAKWLKSYRELPYLYNQWCSVVRWEKSTRPFLRTSE
                     FLWQEGHTLHETAEEAQEETIQQLEVYKALCEELLAMPVVAGQKSESEKFAGGERTYT
                     IEAMMHDGKALQSGTSHFLGQHFTKAFDITFADREGNLANPYHTSWGASTRLIGGLIM
                     THSDNRGLVLPPRVAPIQVVIVPIAAKKGNVMETVDKIYADLKAKGVAVEVDDRDNYT
                     TGWKFNEWEMKGVPVRVEIGPKDIENNQAMVFRRDTLEKDSMPLEGLADAICDLFDVI
                     HNDMFEKARKHREDNTSIVENMDEFRKALEEKPGFIKTMWCGDAECEAKIKEETGATI
                     RCLPFEQENLGHKCVYCGKEADSMVVMAKAY"
     gene            44400..45881
                     /locus_tag="KR294_001094"
     CDS             44400..45881
                     /locus_tag="KR294_001094"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HBH0239182.1"
                     /translation="MNVRVRFAPSPTGFVHIGSLRTALYNYLFAKKMGGEYILRVEDT
                     DQSRLVEGAIENMLNAMKWAGVNHSEGVILDDSGKVVQKGEYGPYIQSQRLDIYQEYI
                     KQLLDSGKAYYCFCTKERLDEVRDAQRAAGETAKYDGHCKNLSKEEVEANIKAGIPYV
                     IRLRLPENHTIKFTDLVRGDMEFNTNDLDDQVLMKTDGFPTYHFAVVVDDYLMKITHV
                     IRGEEWVSSTPKHVYLYEAFGWEAPVFVHLPNILNKEKKKLSKRQGDVAVEDFKKKGY
                     LPEGLVNYVALVGWSPEDNQELFTMEELEKAFSVERVSKSGGVFDTEKLNWVNQHYIK
                     DGDDAYLTDLAIPFLIEDGFITEEEATNKYDFLKSMISVLKEKLQYVKEVTEHASIFF
                     GDKIEVETEEGREFLRLEHIPTLIDALREKIEKTEVLNAEFVQAMLKEIQKEYKIKGK
                     NLFMGSRIILTGQMHGPDLPKVMEVLGKETCLNRIAYVKNNIL"
     gene            46102..46257
                     /locus_tag="KR294_001095"
     CDS             46102..46257
                     /locus_tag="KR294_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239183.1"
                     /translation="MYSNIDDVKKELKELCLEYVTILEKLKDEKMITEETFEKCSSQK
                     KIFLEEQ"
     gene            46402..47799
                     /locus_tag="KR294_001096"
     CDS             46402..47799
                     /locus_tag="KR294_001096"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HBH0239184.1"
                     /translation="MKVYNTLTRTKEEFVPLEEGKVKMYVCGPTVYNYIHIGNARPFI
                     IFDTLRRYLEYRGYDVTYVQNFTDVDDKIINRSHEEGISPEEVAAKYIKEYFVDCDGL
                     GIKRATVHPQVTDNIQQIIEFIKELEDKGYAYAVNGDVYFDTNKFEGYGKLSGQKQED
                     LEAGARIEVNDQKRHPMDFVLWKAKKEGEPGWDSPWGEGRPGWHIECSVMSKRYLGET
                     IDIHAGGQDLTFPHHENEIAQSEARSGKTFSKYWMHNGYININDEKMSKSKGNFFTVR
                     DISKLYDLEIVRFFMLSAHYRNPVNFSDEMLNQAKAGLERLYNTKEKLEFTLSNLVES
                     PLTEKEVELVKELDDFRQKFIDAMDDDVNTADAVSVIFELAKLINSNVDENSSLEFAK
                     KCLDEFNELTGVLNIVNKKKDTVLDKDIEELIQKRTDAKKNKEFQLADDIRQQLLDMG
                     IVLEDTRQGVKWKRI"
     gene            47784..48197
                     /locus_tag="KR294_001097"
     CDS             47784..48197
                     /locus_tag="KR294_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HBH0239185.1"
                     /translation="MEKDIKMEKTELVTMSPLVLAYLGDTVYETYIREYLIRQNTQRK
                     VNDLHKLAIKYVKAKAQATIIHEIEIELTEEESKIYKRGRNQKSNTSPKNADIIDYKH
                     ATGFEALVGYLYLNNEIERLQYIINKGIKIIERDM"
     gene            48303..49061
                     /locus_tag="KR294_001098"
     CDS             48303..49061
                     /locus_tag="KR294_001098"
                     /EC_number="2.1.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent thymidylate synthase"
                     /protein_id="HBH0239186.1"
                     /translation="MKVKLISHTPEPEKVIAMAAKLCYSPVGTDEIEKDLTDESIEKF
                     LNMLLSIGHGSILEHASFTFSIEGISRACSHQIVRHRIASFSQQSQRYVKLEQFEYII
                     PPEIEKIEKAKELFIDSMKKDQENYDKLVEILFENHYNDLIKNGKNEKTAKRQAEKKA
                     IEDARYVFPNACETKMVFTINARSLFNFFEHRCCERAQWEIRNLAVEMLREVKKVAPI
                     LFKKTGPSCVNGSCPEGTMTCGDIVQVREKFKAL"
     gene            49074..49811
                     /gene="rlmB"
                     /locus_tag="KR294_001099"
     CDS             49074..49811
                     /gene="rlmB"
                     /locus_tag="KR294_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HBH0239187.1"
                     /translation="MASIEGRNPVIEAIKSDREIDKILIANSAKEGSIKKIIGMAKDK
                     NIIIQYVDKHKLDEVSTSHSHQGVIAYASEYKYYELDELIDLAKNKDEDPFFIILDEI
                     TDPHNLGSIIRTADAVGAHGVIIPKRRSVHITPVVAKASAGAVEYMPVCKVTNIVNTI
                     KRLKEEGLWIAAADMDGETFYKQNLTGPLGVVIGSEGFGISRLVKQNCDFIVKMPMIG
                     NVTSLNASVAGGILLYEIFRQRLDKSK"
     gene            49814..50341
                     /locus_tag="KR294_001100"
     CDS             49814..50341
                     /locus_tag="KR294_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HBH0239188.1"
                     /translation="MKKNINHYLIIDGYNIINAWDNLKELAKEDLEDSREKLIDDIIE
                     FSEFMGYKTIIVFDAYNVKNSREKVEKRKHITIVYTREHQTADSYIEKFITSLSKYDD
                     VKVATNDYAEQQMILGKGATRMSARELKLELDRSKNKMKEKNIGLRKKIQRNWLEERL
                     DKETLSKLENIRRKR"
     gene            50406..51053
                     /gene="sigH"
                     /locus_tag="KR294_001101"
     CDS             50406..51053
                     /gene="sigH"
                     /locus_tag="KR294_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigH"
                     /protein_id="HBH0239189.1"
                     /translation="MLVAKEKSYELVDNCQQDEYNIVLRASEGDKIALEYIITKYRNF
                     VKAKAKSYFLIGADKEDIIQEGMIGLYKAVRDFDGSKTNSFKCFAEICITRQIITAIK
                     TATRQKHIPLNSYVSLNKPIYDEESDRTLLDIIATSIVTDPEELIISKEELKNIESKM
                     NELLSDLELEVLELYLNGKSYQFIADKLKRDVKSIDNALQRVKRKLEKHLENRND"
     gene            51127..>51461
                     /locus_tag="KR294_001102"
     CDS             51127..>51461
                     /locus_tag="KR294_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosome-binding GTPase"
                     /protein_id="HBH0239190.1"
                     /translation="MAKAKYERTKPHVNIGTIGHVDHGKTTLTAAITKTLYDRYQLGE
                     AVDFANIDKAPEERERGITISTAHVEYETPNRHYAHVDCPGHADYVKNMITGAAQMDG
                     AILVCSATDG"
BASE COUNT        20941 a         5523 c         9749 g        15248 t
ORIGIN      
        1 ccccttccag gtcgccaaaa taaaatgctg gtgtggctca acggtagagc agctgacttg
       61 taatcagcag gttgtaggtt cgattcctat caccagctcc atataaaatt aatacggagg
      121 atttcccgag cggccaaagg gggcagactg taaatctgtt gtcatcgact tcggtggttc
      181 gaatccacca tcctccacca aaaaaatgcg cggatgtggc ggaattggca gacgcactag
      241 acttaggatc tagcgccatt ggcgtggggg ttcgactccc ttcatccgca ccatttttat
      301 ttaatttaat aaacgagcgg gaatagttca gtggtagagc gcaaccttgc caaggttgaa
      361 gtcgcgagtt cgaatctcgt ttcccgctcc aaattttatg tttatgttgt aatgtgggtg
      421 catagctcag ctggatagag caacgccctt ctaaggcgtg tgtccggggt tcgaatccct
      481 gtgcgctcac cacatatata ttggggatta gccaagtcgg taaggcacat gactttgact
      541 catgtatgcg taggttcgag tcctgcatcc ccagccaaac agtatggtct attagctcag
      601 tcggtagagc acctgacttt taatcagggt gtcccgcgtt cgagtcgcgg atagatcacc
      661 aatggagagg tgtccgagtg gtttaaggag ctggtcttga aaaccagtga cttcgaaagg
      721 ggccgtgggt tcgaatccca ccctctccgc caaatgccca gatagctcag tcggtagagc
      781 aggggactga aaatccccgt gtcggtggtt cgattccgcc tctgggcacc aaaatgtggc
      841 ggtatagctt agttggctag agcgttcggt tcatacccga aaggtcatag gttcgactcc
      901 tattaccgct actaaaattt aatgtgggcc attagctcag ttggttagag cgcccggctc
      961 ataaccggta ggtctggggt tcgagtccct gatggcccac cacattaaat taacttatgg
     1021 tgggtatagc tcagttggtt agagcgccag attgtggctc tggaggtcgt gagttcgact
     1081 ctcattatcc accccaactt atatggtcta ttagctcagt cggtagagca cctgactttt
     1141 aatcagggtg tcccgcgttc gagtcgcgga tagatcacca aaaaggcggc gacatagcca
     1201 agtggtaagg cagtggactg caactccttg atccccagtt cgaatctggg tgtcgcctcc
     1261 aataaaatgc gctcatagct caactggata gagtgtctga ctacgaatca gaaggttagg
     1321 ggttcgagtc cctttgggcg caccatatga atagcgaggg attatagctc agctgggaga
     1381 gcacctgcct tacaagcagg gggtcacagg ttcgagccct gttaatccca ccagtgcaaa
     1441 cctctagtaa aactactaga ggttttattt ttgattgaaa aagtttttat atttaggagg
     1501 taaaaaattt gtatatagta ataggaaatg aaatagttga tagtgaagaa cttaaaataa
     1561 ttatagataa aaatagtgaa tttaaagttg aaaaagattt aagtaaaagc acaaaaagag
     1621 aagatgtaat agcatatcag ttaagtatag atttaaatta cctagattct cttataaatg
     1681 agcaatgtaa tttagccagt ctatctgatg aagagaaatt tgatgaatat atgactttgt
     1741 ctgatgaact tgcactggat ttagaagagt taatgccaaa atatacaata ataaatgcta
     1801 gagcatataa attagacgag gtagatggaa ttgtaaaaat aatactagct gtagcgtatg
     1861 cagatttagg gcacttaaaa ctttctgatg tagtaaagag gctatctaga caagtagatt
     1921 aggatatgaa tatgaactat attaaaaaaa tgtataaaat cttacgtaaa gatgaaaata
     1981 attatgtaaa catagaaaaa aacagtataa aatcaagtca attgtagaaa ttttcacata
     2041 aattcatctg aaattctgta aaaaatgcct taattttaat gaggtaaatc gagtttacac
     2101 agtctaaaaa ttacttatat ttataaattt atcttattaa ttaaggaact ttcttaaaca
     2161 tcttcaaaaa taaagtattt tagtctataa tctttaatat tacacaaaca ataaaggaga
     2221 agaatagagt atgcttaaaa agtttaataa aatactagtg gctaatagag gcgaaatagc
     2281 tataagaata tttagagcct gttcagaatt ggggataaaa agtgttggta tatacagtaa
     2341 ggaagataag tatggattgt ttagaacaaa agcggatgaa tcatatttga taggagaagg
     2401 taaagggcca atagatgcat atttagatat ggatggaata atagacctag caaagagaaa
     2461 aaaagttgat gctatacatc caggatatgg ttttctagcg gagaatgcag aatttgctcg
     2521 taaatgtgaa gagaatggaa ttacttttat aggaccatca tctaaggtaa tgaatatgat
     2581 gggggataag attaactcta aaaaaatcgc aaaagaagtt aatgttcaaa ctataccagg
     2641 agtagaaaaa gcaataagaa gtactgaaga agcaaaggaa gttgcaaaca aaataggata
     2701 tcctgttatg ataaaagcat ctaatggcgg tggcggtaga ggtatgagaa ttgtacatcg
     2761 cgaagaagac ttagagcttg aatatgaaac tgcttgtagt gaatcaagaa aagcttttgg
     2821 agaagatatt atatttatag aaaaatatat agctgatcca aaacatatag aagttcaaat
     2881 attaggtgat aattatggaa atatagttca cttatatgaa agagattgtt cagttcaaag
     2941 aagacatcaa aaaataatag aatatgcacc agctttttcg ttagatgata aagtaagaaa
     3001 agagatatgt gaagatgcag ttaagttatc aaaacatgtg ggttattcta atgcgggaac
     3061 attagaattt ttagtagatg caaatggtgg gcattatttt atagagatga acacaagagt
     3121 acaggttgaa catactgtaa cagagatggt tacaggaata gatatagttc aaagtcaaat
     3181 actaatagcc caaggttaca gcttagatag tgaagaaatt aatataaaat cacaagatga
     3241 tgtggaaata agaggttact ctatccaatg tagaataact acagaagacc ctaagaataa
     3301 attcatgcct gatacaggta aaattcaagt ttatagaact ggttcaggat ttggtataag
     3361 actagatgga ggaaatggat ttacaggggc aaacataagt cctcattatg atagtttatt
     3421 ggttaagaca atatcttggg atagaacatt ccaaggagca ataaataaaa ctataagatc
     3481 tataaaagaa cttagagtta gaggtgttaa aactaatgta ggattcctag ttaatgtttt
     3541 aaataatcct atattctcaa atggtaaatg tagtactaag tttatagatg aaaatccaga
     3601 tttatttgaa ataacagaaa gtaaagacag aggaacaaaa ttacttcaat ttataggaga
     3661 tgtaattgta aatgataatg cttgtaaaga aaaaccatta tttgatgcat tacatgaccc
     3721 aagaatggat aaggatggtt caaaatcaga aggaagtaaa atacttttcg ataagttagg
     3781 taaatctgca tatatagaaa agataaaaaa tgataagaaa ttactattaa cagatacaac
     3841 aatgagagat gcacatcaat cattattagc aacaagaata agaacatatg acttattaaa
     3901 agctgctaag ccaacagaaa aatatcaaaa ggatttattc tcacttgaaa tgtggggagg
     3961 agctacttat gatgttgcat atagattttt aaaagaatct ccttggcgta gattacaaaa
     4021 gctaagagaa gaaataccaa gcataatgtt ccaaatgttg cttagagcat caaatggagt
     4081 tggatataaa aactatccag ataatgtaat agaagaattt acaaaagaat ctgctagaca
     4141 aggtatagat gtatttagaa tatttgattc attaaactgg gttgaaaata tgaaaccatc
     4201 tattaataca gctttagaaa ctggaaaaat tgttgaagca actatgtgtt atacaggtga
     4261 tatactagat aagactaaaa ctaaatacaa tctagaatat tatattaaaa tggcacaaga
     4321 attagaaagc ttgggagcag atataatagc aataaaagat atgtcaggtc ttcttaaacc
     4381 atattcagct tacacactag ttaaagagtt aaagaaaaat gtaaaagcac caatacattt
     4441 acacactcat gatacaagtg gaaatggtgt agcaacttgt ttaatggcgt cagaagctgg
     4501 agtagacata attgatgctg cattagaatc tatggcagga cttacaagtc agccatcact
     4561 taatgctata gtagaggcac ttaagaatac agagagagat acaggaatag atttatttgg
     4621 atatgatgag ttaggaaaat attataagga tttaagaaaa gtttataata aatttgaaag
     4681 tgatttaact aattcttgtg cagaaatata taattttgaa ataccaggag gccaatatac
     4741 aaacttaaaa cctcaagctg atagtttagg attagttaat agatttgatg aagttaaaga
     4801 aaaatataaa gaagctaatg aagttgtagg agatataata aaagtaactc catcttcaaa
     4861 agttgtagga gacttagcta tctttatgac taaaaataaa ttagataaag ataatataat
     4921 agaagaaggt aaaaatttat cattcccaga ttctgttgtg gattactgta aaggtatgat
     4981 tggtcaacca gaaggtggaa taccaaaaga tttacaagag gtagttctaa aaggtgaaga
     5041 agctataaca gtaagaccag gttcattatt accagcagaa gattttgatg aaatagctaa
     5101 atatctaaat gaaaagtatg atataaatgc taatataaga aatgttataa gttatgcttt
     5161 atatccaaaa gtatatgaag attatatcaa acatctacaa cattataatg atatatctaa
     5221 acttgaaagt gatgtattct tctatggatt aaataaaaat gaagaatgtg aagtagaaat
     5281 agaagaaggt aaggtattaa caataagatt agttgaaatt ggtgaagtta aggaaaatgg
     5341 atttagaact ataggatttg agttaaatgg aatggttaga gaagtagaaa taaaagataa
     5401 gaatttctct ggaaaaatta ataatgttga aaaagctgat atgaatgacc ctcttcaaat
     5461 tggagcaagc ataccaggaa aagttataaa aataatggtt aaagaagaag atgaagtaaa
     5521 agcaaatcaa ccattaatcg ttatagaggc tatgaagatg gaaactataa tagttgctaa
     5581 gactgatgga gtaattaagt caatcaaagt aaaagaagat gatatggttg aagataaaca
     5641 attattaatg ataatgaagt aatttaatta aaataaatta aaaagcactc tgaaatgttt
     5701 aataaaaaat gttttagagt gtttttattt attttaatta aatatttgtt aaaaaaaaga
     5761 ggacaattac ctccagatgt agaaataaag ctagtaagga aaatgttatc taaaaattct
     5821 aaatatagta aatattttcc ataatatttc ttaggaaata acagcaaaga taaaatacat
     5881 aaatttaaaa ggtgggtgct tatatgaagg tttatgatag taaaatgttg agaaatgtag
     5941 cggtattagg acatagcgga tgtggaaaaa caaatctaat cgaaactata gcttacacag
     6001 caaacactaa taagatacct aaattaacag acaaggtaaa tatgacttat agcatgggat
     6061 taatacctat agagtataat gattataagt ttaacttatt ggatacccca ggatattttg
     6121 actttagcgg agacgttgtg tcatctctta gagcaagtga tgcagcaata atagtaatag
     6181 atgcaacagc gcctattcaa gttggtacag agaaatcatt agaactaact gagagtattc
     6241 ctaagataat gtttataaat aaaatagata atgaaaaggc aagatacaaa gatgcaatag
     6301 caatgttaag agaaaaatac aataataaga tagttcctat gataagtcct atatacaaag
     6361 ataaaaactt tgtaaagtta cataatgttt ttgaaaacat agatgattta gaaggtgaat
     6421 ttaaggaaca agctatgagt gttaaagaag cattaatgga acttatagca gaaactgatg
     6481 accaaatatt agataaatat tttaatggag aagaactaac tacagaagag atacaaaaag
     6541 gtattattat aggtatacaa agaggtgata ttatacctgt aatatgtggt tcaactataa
     6601 ataatatagg cacaaaggaa atattagata caatatcaag ttatttagaa cctatcttta
     6661 cagaggaaag caaaccattt aggggattag tatttaaaac tatggttgac ccatttgttg
     6721 gaaagatgtc atatataaaa attactgagg gtgtactttc taaggataaa gatgttttta
     6781 atataaataa aaatgtaaaa gaaaaaatag ctaatatata tacattgaga aatagtgaat
     6841 tagtagaaat agaaaaagct aaagctggtg atatagtagt tataactaaa gttaattctc
     6901 taaaaacagg agacactata tctgcagata aagatgcaga agctttagaa aagatagatt
     6961 ttcctaaacc acaaatatat tatgcagtaa ctcctaagaa taaaggtgat gaagaaaaag
     7021 tagcatctgt attaaataaa ctagtagaag aggaccctac attacattgg tatagaaata
     7081 cagagacaaa acaagcactt ttaggaggtc aaggagaact tcatataaaa acaattaaaa
     7141 ataaaatgaa agataagttt ggtgttgatg ttgaattgaa tgaccttaaa gttccttata
     7201 gagaaactat aaaaggaaca gctgatgtac aaggaaaaca taaaaagcaa tcaggtggtc
     7261 atggtcaata tggagacgta aaaataagat ttgaaagatg tgaatctgat tttgaattta
     7321 cagaagaaat atttggtggt tctgtaccaa aacaatatat accagcagtt gaaaaaggtt
     7381 taaaagactc tatgcaaaaa ggtatattag caggatatcc tgttacaaac ataaaagcta
     7441 cgctttatga tggttcatac catgatgtag actcttctga aatggccttt aagatggcag
     7501 caagtgcagc ctttaaaaaa ggtatggaag aagcacaccc aatactacta gaacctataa
     7561 tgaaacttaa gataactgtt ccagaagaat atatgggaga tgtcatgggt gatataaata
     7621 agagaagagg aaaaatattt ggaatggaac cagatgacaa agggaaacaa ataatatttg
     7681 cagaagctcc acaagcagag acatttaaat atgcaataga tttaagagca atgacacaag
     7741 gtagaggata ctttgaaatg gaattagaga gatatggaga ggttccatca cagtttgcag
     7801 aaaaaataat tgggttagct actgcaaagt aatgaacaaa ataaatagaa aaataattaa
     7861 tatatattat taaaaatatt tttagggttt taactaggta taggtttatg ttaggtaaac
     7921 ttatacctag tttttataca tttttgatga ataaaaaaat atataatact ttcttaaata
     7981 ttttaataaa aagaaagtat ttttttatta ttatttttac aaatgtttag taataaagat
     8041 gagaaggtat atttaaaata taaagtattt aaagttctga aatctaatca tgaagcaaaa
     8101 aattagcatt tggttatcaa taaatataat aaataaaaac tcataattaa tgaaagaata
     8161 aattcatgtc taaatttcta taaaaaattt aaatttatac aatttagggc tttaaaaatt
     8221 taaataatag gtgtaaaata atagtcaaag aaagtcaaaa ataaaaaggt gtgtggtgat
     8281 attaatggca actatgacag atataattga aaaatttatt aaagatttga tggaagaaga
     8341 taatagcata caaattcaaa gaaatgaact agcaaacttg tttagttgtg caccatcaca
     8401 aataaattat gtcttaacaa caagatttac aatagataga ggatattaca ttgaaagtaa
     8461 aaaaggtggc ggaggatatg ttcaaataga aaaaatacga aaaagtaaag atgggcatat
     8521 tagagaacta ctaaatgaaa aaataggaag tcagatatcc tataaaaaag caaaagaatt
     8581 attagaaggt ttaaaagagt cggatttgat taacgaaaga gaattaaaat taatattata
     8641 tgcaatagat gataaatcat tgtgtatgcc aatatatgaa ttaaaagaga aggtaaggtc
     8701 taatatttta aagaatataa taataggatt atttagtata gaggagtgat aatttatgct
     8761 atgtcaaaaa tgcaataaga ataaagcatc tgtatattat aataagatag tcaatggaga
     8821 aaaaacagag atgtatttat gtagtgagtg tgcaaaagag aatacagaaa tgaattttaa
     8881 cttagatatg cctttttcaa tgatggatat attttctaat ttaggttttc aacctaaaaa
     8941 agaacttgag gaaaagctag tttgtcctaa atgcaataca acatatagtg agtttaagaa
     9001 taatgggaga tttggatgta gtgaatgtta taatgcattt agtagtcaag taaatccaat
     9061 gcttcaaaat atacatgggc atatagaaca tacaggaaaa gcacctaaaa aatcttttta
     9121 taagataagt gtagaaaatg agattaaaga actaaaagaa gatttagata gagctataaa
     9181 aaatgaagag tatgaattag cagctcaatt tagagataaa attaaatatt taaaaggttc
     9241 tattgactaa gattggagtg atattatgaa agagaacata gtcatgaaat caagagttag
     9301 gctagctaga aatttaaata actatccatt tccaaataaa ttagataaag aatgtgccat
     9361 ggaaataata gaaaaagtaa aaaatgcgtt tattaattct aacttagaac aaaaagaaga
     9421 atttgatttc tataaaattg aagatttaga ccaatctaaa aaaatgctta tggttgaaga
     9481 acatataata agcccagatt tagcagaaaa tgataaaagt gcagttatag taaaaaaaga
     9541 taaaactata agtataatga taaatgaaga agaccatata aggatacaaa ctatatgtga
     9601 tgatttaaac ttagaatatg catatagtgt agcaaatgaa atagatgatt tgttagaatc
     9661 aagtttagaa tatgccttta acacaaagct aggttatcta acatcttgtc caactaatac
     9721 aggaacagga atgagagctt ctgtaatgat gcatttacca gcattaagtc aactaggcta
     9781 tatggatgaa ctttataaaa tttcatcaca aataggtata gcaattagag ggatatatgg
     9841 agaacgaaca gaagcattgg gaaatatata tcaaatatct aatcaactta cacttggaag
     9901 aacagagtct aatattatag aaaatgtaag tggacttaca aaagatgcaa tttcaaaaga
     9961 aataaaagct agagaaatat tgcaaaaaaa attaggtata aaactagaag ataaaatatt
    10021 tagatcgata gggacacttg aaaattcaag agtaatgagt agcgcagagg caatgagcca
    10081 tctatcaaat ataaaaatgg gaatagaaat gaactatata gataaactag atttaagggc
    10141 tatagaacaa cttatgatag gtatacaacc agcgcatcag tcaataatgt ataagagtga
    10201 tgatgttgag aatagagata taaatagagc aacatatatt agagaaactt tggaaaaatt
    10261 aagaggaggg atgaattgtg aacttcaata gatttacaca aagagctaaa aaggcaattg
    10321 atttagcgtt tgaatctgct aaaagtctag gacacaatat tgtcggaagt gaacatatac
    10381 ttttaggtct tttaagagaa gaagaaggta tagctgctaa agttctaagt aaagttggat
    10441 ttacagaagc ttatttagaa ggcaaaatag ttgatatgga aggtaaggga gaagaaatct
    10501 cagaagatat agtattaagt ccaagaagta aacaaatact tgaattatca ggaatgtttg
    10561 caaataaatt aaaaacaaat tatattggga ctgagcatat attattagca attattcaag
    10621 aaggtgaagg aatagctaat aagattttaa attatgctgg agtaaatgat aggactttag
    10681 cccaattaac aattgatatg atgggtatta gtgataaaaa tcaatacaaa gcagaaaata
    10741 gttacacggg caaccagaat caagcagaat ctaaagtact tgataagtat ggaagaaatc
    10801 ttacactata tgcaaaacag aataaaatag accctgtaat aggtagagaa aaagaaatac
    10861 aaagagtaat acaaatatta agtagaagaa ctaaaaacaa tccagtgttg ataggagacc
    10921 caggtgtagg gaaaacagcc atagctgaag gtctggctac aaatatagcc ttaggaaatg
    10981 ttccagaaac actaaaaaac aaaactttat actctttaga gatgggttca ttattggctg
    11041 gggctaagta tagaggagaa tttgaagaaa gaattaaaga agttgtagat gaagttgtta
    11101 aaaatggaaa cataatctta tttatagatg agatgcacac aataataggg gctgggtcta
    11161 ctggagaagg ctctatagat gcttcaaata tattaaagcc agccttagca agaggagaaa
    11221 tacaagttat aggtgcaact acaattgatg aatatagaaa gcatgttgaa aaagattctg
    11281 ctctagaaag aagattccaa ccagttatgg tagatgaacc aactaaagag gactcaataa
    11341 aaatattaga aggattaaga gataaatatg aagctcatca taaagttaaa ataactgatg
    11401 atgctataaa ggcagctgta gaattatcaa ctagatatat atcagacaga tatctgccag
    11461 ataaagctat agacttgatt gatgaagctg catcaaaagt aagattaaaa gaaaatacac
    11521 ctccttcaga aataaaaaaa ttagaactag aaatagaaaa tatagataaa gaaaaagaag
    11581 aagcagtaag atgtcaagac tttgagaaag cagccaaaat aagagatgaa caaggtctac
    11641 ttaaaaaaca attagaagat gttagagaaa gatggaacaa gtcatctaaa cattcagatt
    11701 tagttgatgg agaagttatt gctgaagtag tgggcttatg gacaggaata ccagttaata
    11761 aaattcttga agaagaggct gatagacttt tgagacttga ggaaatactg cacaatagag
    11821 ttataggtca agaacaagca gtaaaatcta tttcaaaggc aatcagaagg tcaagagcag
    11881 gtcttaaaga ccctaataga ccaattggtt catttttatt tttaggtcca acaggagtag
    11941 gtaaaacaga attatctaag gcattagcag aagtgcaatt tggagatgaa aatcaaataa
    12001 ttagaataga tatgtctgaa tatatggaaa aacatgctgt gtcaagaatg ataggttcac
    12061 ctccaggtta tgtaggtcat gatgaaggtg gtcaattaac tgaaaaagta agaagaaatc
    12121 catattcagt tatattattt gatgagatag aaaaagctca tccagatgta tttaatattc
    12181 tgttacaaat tctagatgat ggtagactaa ctgattcaaa aggaagaact gtagatttta
    12241 agaatactat tgtaataatg acatcaaatg ttggagcatc tacaattggt agacaaaaaa
    12301 ctttaggatt tagtatagct aaaggagacg aagaagaaaa atctcaatat gaaaaaatga
    12361 aagaaaatat aatgggtgaa ttaaaacaaa gattcagacc agagttttta aacagaatag
    12421 atgatataat tgttttccac tcactaaatg aaaatcatat atcaaaaata gtacttttaa
    12481 tggcagcgaa actacaagag agattaaaag aaatggatat aaaattagaa atgagtgatg
    12541 aggctgttaa attaatttct aaatctggat ttgacttaga atatggagca agacctctta
    12601 aaagagcttt acaaaaagag ttggaagatg agctatctga agcaatctta aaaggtaatg
    12661 tgaaaaaggg aagtaatgta gtagcaaaag tcaaagatga aaaaatagtt tttgaaacta
    12721 aataatttaa tagagttgca ttttaaaata ttgcaaatat aagttttata atctaaacaa
    12781 aattttaagg gcaatgaatc tataataatt cattgtcctt aattatttta tttaatcttt
    12841 acatattgtc tttcagatat gctaaaatta tagtatagaa taaaaaatta aggatgataa
    12901 aagtatggca aaaataaaaa caaaatatgt atgtcaatct tgcggatatg aaacagctaa
    12961 atggcttggt aaatgtccag aatgtacaaa atggaataca tttgtagaag aaatagacca
    13021 aaaaagcacc aaaaaagagg tctttataat agataaatct tcatctaaac cagtcagtat
    13081 aaactcaata gaaagtaaag aagaagagcg gtttacaaca gatataaatg agttagatag
    13141 agtgcttgga ggaggtatag ttaaaggctc tttagtgctt gttggtggtg accctggtat
    13201 aggtaaatca acacttttaa tccaagtatc tagtaatgtt gccaatttag gaaaaactgt
    13261 tttatatata actggagaag aatcagaatc tcaaataaaa atgagagcta aaagattagg
    13321 tattaactca gaaaatttat atatatttgc tgaaaataat ttaagtataa ttgaatctta
    13381 tttagaaagt gtaaatccag aattaataat tctagactca attcaaactg tcttcagtcc
    13441 agaaatatcc tcggcaccag gaactgtcag ccaaattaaa gaaggtactt caaaattcat
    13501 gaaaatttct aaaaaaatgg gaatttcaac gttcatagtt gggcatgtta caaaagaagg
    13561 ttcactagca ggaccaaaat tattagagca tatggttgat actgttctat attttgaagg
    13621 agaaagatat aatacttata gattagtaag agctgttaaa aatcgatttg gttcaactaa
    13681 tgaacttgga gtatttgaaa tgagggattt aggattagta gaacttgata atccatctaa
    13741 aattttaatc tctgaaaaac caaaagatgt agcaggttca gtaataatat ctactgtaga
    13801 aggtacgaga ccaatgttac ttgaattgca agcattagtt tctcctacaa gttttggtat
    13861 accaaaaaga acatctacag gagtcgatta caatagagta ggtatgttat tagcagtatt
    13921 agaaaaacgt gttggtttgc aaatacaaaa tcaagatgtc tatataaaca tagttggagg
    13981 aataaagata aatgaaccct caattgattt agggatagcc atttctgtag catctagttt
    14041 tagaaatata ccgatagatg aagatatagc tgttacagga gaagtgggac ttacaggaga
    14101 agttagagca gtaagcttta tagaaaagag aatagctgag tgtaaaaaac ttggatttaa
    14161 aaagatagta gttcctagaa gtaattatga tgttgtaaaa gagaccaaag gcatagaaat
    14221 atggccagta gataacttaa gacaagctat aaatatagta cttgggagga atcaataaat
    14281 atggagaatt ttctagataa taaaaatatg ctatatgcat taaaaatgat atctcctgga
    14341 actccactta gattaggtct aaacaatgta ctaagagcta agactggtgg attaattgta
    14401 attgcaacaa acgaagatgt aatgaaaata gtagatggag gatttgctat aaatgcagaa
    14461 tattcaccat catatctata tgaattagct aaaatggatg gagctatagt tttaagtggt
    14521 gatgtaaaga aaatattatt tgctaatgca caacttatac ctgactattt tatagaaaca
    14581 tcagagacag gaacaagaca tagaacagca gaaagagtag caaaacaaac tggtgctata
    14641 gtcataggaa tttcacaaag aagaaatgtt ataacagttt atagaggaaa tgagaagtat
    14701 gtagtcgaag atatatctaa gatatttact aaggcaaatc aggctataca aactctggaa
    14761 aaatataaga cagtattgga ccaagctgta acaaatttaa atgccttaga gtttaatgat
    14821 ttggtaacta tttatgatgt tgcattagtc atgcaaaaga tggaaatggt aatgagagtt
    14881 acaagtataa ttgaaaaata tgtgatagaa ttgggtgatg aaggaacttt agtaagtatg
    14941 caattagaag aattaatggg tacaaccaga atagaccaga aattaatatt caaagattat
    15001 aataaagaaa acacagaaat aaaagaactt atgaaaaagg tcaaaaattt aaattcagaa
    15061 gaactaatag aattggtcaa tatggcaaaa ctattagggt atagtggttt ttcagaaagt
    15121 atggatatgc ctataaaaac aagaggttat aggattctta gcaaaataca tagactacca
    15181 acagcaataa tagaaaactt agtaaattat tttgaaaact ttcaacaaat tttagatgca
    15241 tctattgaag aattagatga ggttgaagga ataggtgaaa taagagcaac atatataaaa
    15301 aatggactca taaaaatgaa acaattagtc ttattagata gacacatatg atgaatttta
    15361 aatgaatttt actacttttt tcttgaatat aatatacact ttggtctata atagataagt
    15421 ataactaggg ggtgaagcat tgataaggaa agtaacaaga atattgttta ttttacttgg
    15481 atttacaata ggtataacaa cctatttaac attaatgaaa gattttgaaa tattaacatt
    15541 tggaaaagaa acatatggtt atatcgcagc tgtagtagca ggtataataa tagccatttt
    15601 aggatatctt atagaaccat gggttgtaaa taaagtaaaa gaaattgcta aaatagtgga
    15661 taaagaattg tcaaaatatc ctcagactga tatattgtta gggtctatgg gtcttatagt
    15721 aggatttgtt attgcgtatt tattaagtgg attagtaaat agaataccaa tagtaggtgg
    15781 aatactatcc ttactattat atttattcct aggatatctt ggaatgaaag ttgcgcttaa
    15841 aagtaaaaat gatttattta atattggaaa actaggaaga ttagcaaatc ctattaagga
    15901 taaagataag gataaagaaa ataaaaaaga agtaaaagcc attcctccaa aagtattaga
    15961 tacaagtgta ataattgatg gaagaatagc tgatatttgt aagactgggt ttatagaagg
    16021 aaaacttatt attcctgctt ttgttttgga ggaactaaga catattgcag attcttcaga
    16081 tgatttaaaa agagtaagag gtagaagagg tctggatata ttaaatataa ttcagaaaga
    16141 attaaatata gaagttgaaa taagtgagag agactttgat gatatagcag aagttgatag
    16201 taaattatta aagcttgctc aggttttaaa tggaaaagtt gttacaaatg attataactt
    16261 aaataaagtt gctcaattcc aaggtgttga agtattaaat ataaatgagt tagctaatgc
    16321 tataaaacca gttgctatac caggtgaaga tatggttgtt caagtggtta aagaaggaaa
    16381 agaggctcaa caaggtgttg catatctaga tgatggaact atgatagttg ttgatggagg
    16441 aagaaaatat atgaatgaga ctataaaagt actcgttact tctgttcttc aaactcctgc
    16501 aggtagaatg atatttgcaa aacctaaaaa ttaatatgtt caaagaaacc tataatttgg
    16561 gctgtttatt ttaaatagat ggtccaaatt tatttattta taacgataat gtttaatgta
    16621 ttcttaaaga tggggattta aatcagaaag cagggagaat ttatgagaaa aaagattata
    16681 tctttcttag caacatttat cataatatta acatcagcaa gtcagtatag ttttgcagat
    16741 gatatatcaa cacgtggaaa agtaatattt atagatatga atagaactag tatgagtaat
    16801 atgttaagaa taaaatcatt aagagaagaa ctagacaata gagggtatat tggcttgatg
    16861 aatataagag gcgataaagg aagtgatgat agaaggtcat atgctagtat gggtgctggt
    16921 ggtagagcta atgtggctaa tgaagaagat attaattttg aaagctcgag taaggataga
    16981 aatatagttt ttgaatcagc tacaggaaaa agtgcaaaag gtataaataa tttaactata
    17041 aataagtcta taaatgaaaa tttaaacttt ggagagtatg gttctgtatt agggtcatta
    17101 ggacaaagtt tatctgataa tggattaaaa gcatctgtat tgggtaattc agatataatt
    17161 gaaaatggtc aacttataaa aaatagaaac ttatgtctaa ctgcaatgga tgaatatgga
    17221 agaataccta atggaaatgt agatactata aataaaaaag acttatctat gccttatgga
    17281 atatcaactg attatgataa attgattgta gagactaaag aaacttacaa aaataatgat
    17341 gtgatttttg tggagcttgg agacacatat agattagatt tatataaacc aaatttaaat
    17401 gaaaaaacat atgagagtat gaaagataac atagaaaaaa atatagatat atatttaaaa
    17461 aatatatttt ctatggttga agaaaatgac actatctaca tagcaagtgc atttccaagt
    17521 gatttagatt ataaaaataa aagaagactt tctccaataa taaaattaaa tggagaaggg
    17581 aaaggtatat tatcatcttc aactactaga agagaaggta ttgtaacaaa tttagatgtt
    17641 ggggttgaaa tattagacaa ctttaatata aaaaatcaaa atatggttgg aagaaaatat
    17701 gaacttatta acagagatga taataaagaa tttttgatgg atgaatatca aaagatagta
    17761 tctatttcaa gcataaggtc tacaatactg aatggttttg taagtatagt tttcttgtca
    17821 tggatagttg ctatgattgc aattttattt agaaagcata tatcaaaaaa ttataaagaa
    17881 acaacatttt ttatattaaa ggaactttta aaaataggaa tagtaatgcc actgtcattt
    17941 atgataacac caataatgaa tttcaaaaca ccattagcaa tatctttagg aataattata
    18001 ataacactta ctatatatct tataagtaaa gttttaataa agaacgattt aaaaaacatg
    18061 ctgtttttta ctggattaac catagtaatt atggttattg atgctgggtt tggctcatat
    18121 ttaatgaaaa gcaatgttat gagttatgat tgtataattg gagctagata ttatggagta
    18181 ggaaatgagt atcaaggtgt ggcaatcggt agtgcaatat ttacatttgc aattttactt
    18241 acatataaaa atataccaaa gtggtatata atagtttttt ctttggttat cttaattaca
    18301 agtgcatctc caattatggg agcaaatgtt ggaagtgcta tttctgaatg tgttgcattt
    18361 ttactattta tactattgat atataatgta aagatagatt tcaaaaaaat cgtattatta
    18421 ggtatagcag tagtatttgt attaggagtt tttgtagcaa tagatatgat tttgggaagt
    18481 aattcacatt taggtatgtt tgtaaaagaa atttacttta atggaccagg agaaataata
    18541 caaacattta gtagaaagat agagatgaat ttaaagctag ctcaaaccag tgcatgggta
    18601 aatatactgt taactggaat aggtgtaatt ttagttctta tgattaatca gattagatac
    18661 tttaagcaac tgatggatga gtatccaatt gtatttaaag gatttatagc atcaatagca
    18721 ggatgtttag taactctttt agtgaatgac tctgggattg tgtcatcagc tacagccttt
    18781 atttatgtaa ttgtacctat gataacatta agtataaatc ttacagcatt aaaagaataa
    18841 gtactgtatg aataatatgt aaatattaat acattaattt aacttcttta tttacaaaat
    18901 aaagaagaaa gtttataaaa aataaattat aataaaaaag agtttatctc aaaattgatt
    18961 attctaatca aattttaaga taaacttttt ttattataaa gataaataac atataacctc
    19021 atattttagg tagatttttt tcttatatgt ttaggagtgc atttaaattt ttccttaaaa
    19081 attctgtaaa ataattttgt attagtaaat ccatgagctt ctaatatact gcataaggta
    19141 tcatttgtgt taattaaatc tttataaata tgagaaatac gcacatcatt taaatactct
    19201 aagtaagttt gtcccatata ctgtttaaat tttctacaaa aatattctgg ttgtaagtgt
    19261 gctaccttag cgattttgtt aatagaaata ggcattttgt aattaatctt tgtatattct
    19321 aaaactggtt caaattttga caaatcaagt actgtttttt tcatattttt attacctaca
    19381 gatattttaa agtttgtata taattcaaat aaaagttcaa ataataagct tgtaaagagc
    19441 agattagctg caggaggaga actaagttta atttctctca tgttttctaa tataagttta
    19501 actttacttg aatttttttt atagttattg tcattggcat taaccttaaa gtcaaaatag
    19561 caatttttaa aatcagggat atatttgttt agaaaagaca atggtacttg caataatata
    19621 gaggtatttt gataaataca tctagttgag tgaataattc cagaattaat gaacatacac
    19681 tcattagctt ttaaattata agtgtaaccc tccatgttaa tttgtaaatc accagaagtt
    19741 atataaatta tttctaatga gttatgccaa tgatttgcta cataactacc actatcatca
    19801 aatagtttga aattaacatc taaattatca ataggttcaa ttatttcatg tgaaaaatta
    19861 tttctgttca taataatatc ctccttataa ttttaaatta taaatagtaa atttataatg
    19921 ttcaatatta aaaagataat atagactaat aaattagata ataaacatac ttaagaaaac
    19981 ggataaaatc aaatataata actgtatatt aaaataactt aaaaaaatta ttttattata
    20041 agtgcaaaat atacctattt aaataagata agaggggagg attttatgtg tatataaaag
    20101 gtgtaaattt aggaggttgg ttagttttag aaaaatggat gacctcaagt ttatttgaag
    20161 gcacagaagc tgaagatgaa tactatttac caagacagct ttcaagagag gcatatgaat
    20221 ctagaattaa gactcatcgt agtgaataca tcacagagag agattttgca acgattaaat
    20281 ctatgggatt taattcagtt cgtataccag taccatactt tatttttgga gattgtgaac
    20341 cattcatagg atgtgttaaa gaacttgata aagcatttgc ttgggcagat aagtatgggc
    20401 ttagtatatt gatagactta catacagttc caggaagcca aaatggattt gataatggag
    20461 gaatatcagg tatatgtagc tggtcacaaa atccagaata tgtagcgttt acattaaatg
    20521 tattagaaag acttgcaaaa cgttatggga tgaggcatga attgtatgga atccaaattt
    20581 taaatgagcc tataacagaa agaatgtgga acataatgaa tgttccaaat cggtttaagg
    20641 ctgtagataa ggagatggca agggggagta aacctaattc attagagttt ttacgtgatt
    20701 tttatataaa agcatatagg gtaatgcgtc cttatatgag agaggaaaac gttatagtgt
    20761 ttcatgatgc atttgaatta aaagcatgga aagactttat gagagaggaa gaatttaaaa
    20821 atgttgttct agatacacac caatatttga tgttagctga agcagatgga tgtgaacaaa
    20881 gtattgatag ctatctcaaa tatattagag aaaattatgc taaagatatt ttacaaatgc
    20941 aaaaatattt tcctgttata tgtggggagt ggagcttatt taattcatat gtttgtggta
    21001 tagatacaaa tggaggtcaa tcacctctaa atgggattga atcaaatata gataaattat
    21061 caaaagacga taaaagagaa ttatatagga agatagcaaa agcacagctt gatgcatgga
    21121 gaaatggaag tggtcactac tattggaatt ataagttatt actagataca gttaatgaag
    21181 aaggttggat aggatgggat agttgggacc taggcaaatg tgtagctcaa gaatggtatc
    21241 ctatagaata ttaaactaaa attggaggaa aagatatgat taaaaaccct atacttccag
    21301 gttttaatcc agatccttgt atttgtagaa agggagatga ttattatctt gtagtttcat
    21361 cttttgaatg gtttccaggt atacctgttt atcactctaa agacttaaaa aattgggagt
    21421 tatatactca tattttgaca gatgaaacaa aaatagattt gaagaagctt ccttcatcta
    21481 aaggaatttg ggcaccctgt ttgacttatt gtgaagaaga agatttattt tacatagttt
    21541 atggaattat gaactctatg aatgcaagat attttgatgt tgataattat ttaattacat
    21601 caaaagatat aaagggagag tggagtgaac cagtatatct acactcatca ggttttgatg
    21661 cgtctatttt tcatgatgat gatggtaaaa agtggattgc atcattagac tgggagacta
    21721 gagaaggata tgaaaaacct ggtgttatat gtttagtgga atactgtaca aaaaagaaag
    21781 aaatagtagg atatccaaag agaatatggt cagggggaac tgatagaggt tgtattgaag
    21841 caccacatat aacaaagcgt ggagattact attatataat gtgtgcagaa ggtggaactg
    21901 gatatggtca tagtgtaact atgggaaggg ctaaaaatat atggggacct tatgaaaaag
    21961 attcaatgaa tccaattgta acttcaattc caggcgattt ttatgaaaga catgaccctg
    22021 accatctaaa gcctaaatac tataatccag aatcaaaact tcaaaaatct ggtcatggaa
    22081 gctatataga aacaacatca ggtgaagtat atttagttca tctaacatct agaccatttg
    22141 taccagagtt aaggtgtact ttaggtagag aaacagctat tcaaaaaatg aaatggacaa
    22201 aggataattg gcttcgaatg gaagatgaaa gtaatttggc aaaagaatac gtatcagaaa
    22261 gtaaactaga agaacattta gtttcatcta taccaagttt tgatgacttt gattcaaatg
    22321 aattaggttt acagtactat gctcctagga tttcaccatt atcatttgca gatgttaagt
    22381 ctagaccagg atatgtaagg attagaggac aagaatcaag aacatcatta aataaagtaa
    22441 gcatattggc aagaaaatta acttcagtat atgcaagaat aaccactaag atggagtttt
    22501 acccagaggt acatcagcat agtgcgggtt tgataatgta ttatgataat atgaattata
    22561 taaatttaag aaagtattat agtgaaacat tgggtcaaag tgcactatca ataatacatc
    22621 ttgaaaatgg agagaaaacg gaatttttaa atactaggat accaataaaa gatataccaa
    22681 tatatcttcg tctgtatata caaggtcgta agtcatattt tgaatggagt tatgatgaaa
    22741 aaaactacca gagaatagga aaggtatttg atacaactaa gttttcagat gagtactgta
    22801 aatatggaga atttacaggt acgtttatag gattaacttg tgcagatcgt gtaaagcata
    22861 aacactatgc tgattttgat ttttttgaat atatagtaga tgaatcaaaa gatgtcgatt
    22921 aataaaatca ttactaaaat tttcagagca aaggtaaatc ttatgctctg aaataagaaa
    22981 cattagaagg caaatcttac aaaaaggagt atggtattat gaatacagaa gttaatgtta
    23041 aagcaactac gattagatat gaaaagattt cattttttga aagaatttct tatggttgtg
    23101 gggatttggg gtgcaatatc atatactcag ctatgtcagc atttttgctg ttttattata
    23161 ctaattatgc agatgttagt gcagcagctg taggtagtat tatgcttgta tctaggatac
    23221 tggatgggtt tagtgactta acaatgggaa ttatagtgga tagaactaaa tccaaatacg
    23281 gtaaggctag gccttggatt ttgagaatgg cgattccttt tgctatagca gcagtattat
    23341 tattttctgt tccatcaaat cttggtatca cttctaaatt aatttatatt tttattacat
    23401 ataacttagt ttctactgtt atttatacag caatcaatgt accctatgca actctaaatt
    23461 cacttataac tcaaaaccag tatgaaagag gagtattaag tatatttaga atgatattag
    23521 ccacttgtgg taccttacta ataaatggac ttacactacc tctagttgaa tactttggaa
    23581 ataatttatc agcatggact aaaacattct ttgtatttgg aatagcatct ataatggtat
    23641 tttttataac atttactgga accaaggaaa gagtaaaagc agttaagcaa gataggaatg
    23701 aagtaatacc atttaaaata ggtattaaat ctttatttag aaataagtac tggatacaaa
    23761 taacattatg tttagtttgc atatttattg tatttgcgat aaatggtggt tcatccgtat
    23821 attatgcaaa gtttattttg ggagatgaaa aattatttgg tcctataaat atggtttcaa
    23881 atatatccca aattatagct atgtttatgg ttgctccttt tataaaaaaa tttggaaaaa
    23941 gaaatgtatt aatagtaggt tcaataatat taatatcgtc aaatgttatg tttataatag
    24001 ttggacaaaa tcatatagga gtaatatttg caagtgctat aaagggaata ggaagtgctg
    24061 gaatagcatc aacaatgttt gctattgttt cagatactat tgaatatgga gaatggaaga
    24121 ctggatatag aactgagggg cttataaata gtgcatctag ttttgggttt aaagtgggaa
    24181 atggattagg ttcagcaata ttaggtgcag tattatcaat tggtggttat gtaggaacat
    24241 cagctactca aagtgattta gctatagtat caataaaagt atgttttata tacctaccta
    24301 tatttataac aatattacaa attatcataa tgtcttttta taagcttgat aaagaatata
    24361 gtactatact taatgaatta aatactaaat aatgaaaaag tttcttataa agtcttaagt
    24421 ttaattaagg tctattgtaa atgttcccta taaaaactat tatatattta tgattattga
    24481 agaattttta gagaagcgaa taataaaaat ataagaagac tttaaatgat gaaatggttg
    24541 gttttttaga aatgatttaa taagttattg ttatttaaag cattataagt ggacaattaa
    24601 tttttaattt atggagatga tatttaacaa ttagaagtaa tatataatat gcactaagaa
    24661 gcaatttttc aactatttat gaaggtggtg gtacaagaaa agtatcacct tttttttgtt
    24721 atacaaaaaa acagttgact ttttatatga accccttcta taatgttact gaaattaagt
    24781 aaaatgattg aacaaatgta aagataattg aaaagcttga ttttggagga aagcaaatga
    24841 aaaaaattgg agacttaaga ttaatgatga agtgttgttc actttattac gaagataatt
    24901 tgaatcaaca ggaaatagca aatcaattgg gaatatcaag accaacaata tcaagaatat
    24961 taaaagaagc ttttgaacaa ggaatagtaa aaatacagat agttgatgtt ttgaaaaatg
    25021 attaccaaaa aatagagaga agtttggaga gaaaatataa attaaaagaa gtaatagtag
    25081 tagatgataa acaggatgca ctaacacaaa aacaagaact agcaagagct gtatctgaat
    25141 atttaactag agtagtaaag gaaaatgata taataggtgt ttcaatagga acaacactaa
    25201 aagaaatacc aagatatgtg gaaaaaagta actgtaaaaa tgttacattt atacctctat
    25261 taggagggat tggagacaat gaaatagata ttcatgcaaa tcaaatagcc gtaagtttag
    25321 cgagggcttt tggaggtgat tttaaattat tacatgctcc agctgttatg tctgacttgt
    25381 ctacaaaaga gaaactttgc aaagacgaaa aaattaaaga agtactagat ttaatagata
    25441 aaacaactat agcaattgtg ggtataggaa atcctatgag tttaaactca acaataatgg
    25501 cttctggata catgaatgaa gcagatatag aagatttaaa aaaatacaac tcaataggtg
    25561 caatttgttt acaagccttt gataaagaag gaaaaacttc tatacttgaa tttaatcaaa
    25621 gagtattagg agtgaaactg gaagatttaa aaaagataaa aagaacaata ggtgtcgctt
    25681 caggagatga aaaaatagag gcaataaagg catcattaaa agcgaaattt ataaatagtt
    25741 tagcaattaa tcacagttta gcacttaaat tattagaaga ttgtgactaa tagaaagata
    25801 gataaaagtt aacaggaggg aatgtatatg tcaatatcaa aagaaacatt gcttgaaatg
    25861 tataagagaa tgaatcaggc tagaaaattt gaagagaaag ttagttggtt ttttgcaaga
    25921 ggtatggttc atggaacaac tcacttatct gtaggtcaag aagcgtcaag tgtggcggct
    25981 gtaatggctt tagaaaaagg agatttagta tcattaactc atagaggaca tagtcaattt
    26041 ataggaatgg gaatagacct aaataaaatg atggctgaac ttatgggtaa agaaactgga
    26101 ttttgtaagg gaaaaggagg ctcaatgcat atagcagata ttgagtcagg taacttagga
    26161 gcaaatggag ttgtaggtgg aggtcttaca atagctccag gagctgcact tacacaacag
    26221 tataaaaaaa caggcaaaat agttttatgt agttttggtg atggagcatc aaatgaaggt
    26281 acttttcatg aaggaataaa tttatcttca atatggaaat tgccaataat attttactgt
    26341 gagaataatt tatacggtat gtcaacaagc ataaaacgtc atatgaatat agaaagtatt
    26401 gccactagag cagcttctta tggaatagaa ggaatatcaa tagatggata taacccaata
    26461 gaagtatacg aaacagtaca aaaagctgct gagaagtgta gaagaggaga aggacctgta
    26521 ttaattgaaa gtagaactta tagatggtta ggtcattcaa aatcagatgc aaatgtatat
    26581 agaacaaaag aagaaataga atcatggaaa gcaaaagacc ctattgaatt tttaaaaaat
    26641 tatcttatag aaaataatct atctaatgaa gatgaattag ataagattca agaatttgca
    26701 aagcaatcaa tagaagatgc agtagagttt gctcaaaata gcccaaatcc aaaaatagag
    26761 tctttattag aggatgtata tgcagactaa gaatggtaaa ggaggaaaat aaaaatgagt
    26821 acaagggaat taacatatgc acaagcaata aaggaagcaa tgtcagaaga aatgagaaga
    26881 gatgaaaatg taatatttat gggagaagat ataggaatat atggaggagc atttggtgta
    26941 tcagttggta tgatagatga atttggacca gaaagagtaa gggatactcc tatatcagaa
    27001 gcagctatag caggagcggc agcaggtgca gcagcaactg gcttaagacc tattatggaa
    27061 gtaatgttta tggactttgt aacaatttct atggatgcaa ttgtaaatca agcggcaaaa
    27121 atgagatata tgtttggagg aaaagcacaa gttccaatgg ttgttagatg cccaggaggt
    27181 tctggaactg gttcagcaga gcaacattca caaagtttag aagcttggtt ttgtcatgta
    27241 ccaggagtaa aagtagttgc accttctaca ccagcagatg ctaagggatt gttgaaagca
    27301 gctataagag ataataatcc agtcatattt gttgagaata aattgttata cagaaaaaaa
    27361 ggttttgtgc cagaagatga ttatgtaatt gaaattggaa aggcagatat taaaagagag
    27421 ggtactgatg ttacagtaat tacttatgga agaatgttac aaagtgttga agaagcagca
    27481 gagactctat caaaagaaaa tataaatgtt gaaattatag atttaagaac tttatatcca
    27541 ttagataaag agactatagt aaagagtgta tgtaaaactg ggagagtttt aatttgccat
    27601 gaagcagcta agactggtgg gctaggtgga gaaatatcag ccctgataac agaaagtgaa
    27661 tcatttgatt atttagatgc tccagtaaaa agaatttgtg gaaaagatgt gccaatacca
    27721 tataatccag agttagaaaa agcagttgtc ccaagagttg atgaaataga agaagcaata
    27781 aaatctttaa ttgttagata aggagggata gatatggtgg caaataaaat aaaagccaca
    27841 ccagcagcta gaagtcaggc aagaaaagac aatataaaat tagataggct gattggaagt
    27901 ggagaaaatg gaaggattca tttagtagat gtgttaaatt atttaaaaga taataaagca
    27961 aatactactc ctttagctag aagaatagca gaagatttaa atatagattt agaaactatt
    28021 gtaggtactg gatataatgg aaagataaga aagtgtgatg tggaaaaatt aactggaaaa
    28081 gaaactattg tatcaactaa tacatctaaa tctagtgaga aaaaagagct gaaaattgaa
    28141 aatgaaaatt caagaatgtt taacacagta gaaggaatat ttgaaaagcc aaatccaatg
    28201 agagctactg tagcaaaacg aatgtcagaa agttatttta gtgctcctgt atttacattc
    28261 aatatagaag tagatgctac agaattgaag gtacttagag caaagttaat cgacacagta
    28321 aaagaatcaa ctggagtaaa attaactatg acagatttaa tagtaatggc agtatctaaa
    28381 atacttccaa atcatcaagc cttaaattca gcatggacag atgagggtat atttagatat
    28441 aaagatgtaa atatagctat tgcagttggt ttagatgaag gcttatatgt tccggtagta
    28501 aaaaatgcaa acaaaaagtc tttaaaagaa atagcaaaag aaagcaaaga acttgcggaa
    28561 aaagtaaaga cagggaaact tatgccagca gaccaagaag gtaatacatt tacaataagt
    28621 aatgttggaa tgtatggtat aactacattt acacctataa taaatatgcc ttcaagtgca
    28681 atcttagggg taggtgctac acaagataag tttgttccag taaatggaga ggctaaaata
    28741 aaacctataa tgaacttatc attaacatca gaccatagag taatagatgg aacagtagct
    28801 gcaaaattct taaaagattt aaaagaattg ttagaaaatc ctttatcaat gcttgtatag
    28861 gttttgatat tttgttactg atataaatag tttgaataga ttatattatt ataattgttt
    28921 cagtaaattt aaagctttta tatattaaga attattttta acagtaacta tatgtgaata
    28981 tgatttgctt aattaaaata tatgaaaata aataggagga gagcctatgt cagtagaagt
    29041 aataatgcca aaagcaggag tagccatgga agaaggtact atagtatctt ggctaaagca
    29101 agaaggcgaa gaagtaaaga ttggagaacc tatactagaa ataacaacag ataaagttaa
    29161 tatggagata gagtcagaag gagaaggtac acttgctgta atcatacata aagaggaagg
    29221 tgaagtatta ccagtattta cagtaatagg tgtaatagca gaaaaagggg aaaatcaaga
    29281 ggaagtaaaa gctaaatatt tatctggaaa tgtttcaaaa gaagatatag ttgaagagaa
    29341 tcaaaatata gaatttaaag aagaaaaaat aaacaaaaaa gagtgtaatc atgattatga
    29401 tgtagtggta ataggaggag gacctggggg atatttatca gcattaaaag cagctctttt
    29461 aggtggaaga gttgctttag ttgaagaaaa tatactagga ggtacttgct taaatagagg
    29521 ttgtatccct acaaagactt atataaaaac agcagaaata ttagaagaaa ttgaccaatt
    29581 atcaaagaga ggtgtaaaag taactgtaga taaagaacag gacattaaga aggccataaa
    29641 atataaaaat agagtagtta aaaaacttac agctggtgtt ggcggattat taaaaagtag
    29701 agatgtagat gtgtttaatc ttaaagctag tgttaaagaa gagcataaag taattttatc
    29761 agatggaaaa gttttagata cagaaaatat aataattgct acaggttcca aagtaaggat
    29821 attacctata aaaggaatag aatcaaattt aataataact agtacagaag cattagattt
    29881 ggaaacagtg ccagaagaat tagtaataat tggtggtgga gtgattggtt gtgaatttgc
    29941 agagatattc aattcaagag gttctaaagt aactatagta gaaatggaag atagagtaat
    30001 cccaagaatg gataaagagt taagcgaatc tttaaaatat tctcttagta aaaaaggtat
    30061 aaatgtatta actaaaaaga aagtttctga atttaaagaa gaaggaaata acatattagt
    30121 gtgcattgaa ggtgaagagc caataaaagc agatttatgt ctatatgcta taggaagaga
    30181 agctaatctt tctggcatag aggacttaga tattaaaata gataaaggtt caatagttgt
    30241 aaatagtaaa atggaaacaa gtataccaag catatatgca gtaggtgatg ttactggagg
    30301 tgtaatgtta gctcatgctg cttttaaaat gggagaggta gcagcttcaa atgctctagg
    30361 tgtgaataaa gaagttgact taggtgcatt acctagttgt gtttatacaa ttccagaagt
    30421 agcatcagtt ggtattacag aagaggatgc tagaaaaaaa tataatgtaa aagttggtaa
    30481 gtttaatttt gctggaaatg gaagagcttt agcttctggt caagaacaag gatatgtgaa
    30541 ggtagtagca gatgctaaat atggagaaat tttaggtata catatgtttg gatgtggtgt
    30601 agcagaactt ataaatcatg cagcatcatt taaagcgtta gagataccta ctgatgaagc
    30661 aagtgagttg atatttggtc atccatgtac ttcagaagct ttaatggaag ctttggcaga
    30721 tgtaaatgga gaatgtttac acttacctaa aaaataaatc taaacataaa ttattaattt
    30781 aagtctatta ttaatattaa tttatatcat aaaattttaa aacacttact tagccatacc
    30841 ccttattatg caaataattt atttgcataa taaggggtat tttttatgga aaaatataga
    30901 atatagaatc cttgtagttt ttgttgtaca aaaaagatag taatataaaa taacattatc
    30961 attttagaat gatttcaatt gtaattagga aaagtgattt ttttgttttt aaaaaaagta
    31021 ttatttgtaa aatataaaaa aaaatttctt aatatttgaa taaaagaata gcttaattta
    31081 aatgttatta ctttataaaa aaataataag tacaaaaaaa acaatatatg gcatataagt
    31141 tgctatataa ataataagga gggaacaatt ataaatgagg caaagaataa aaaacttaat
    31201 tgaaaatgaa gataagaaaa atcctttaac agatgaagcg atttcaagta ggttaaatat
    31261 tcgaagagaa gatgttacct ttttgagaaa tgagttaaaa atagaagatt caagacaaag
    31321 aagaaaagtt gttttaatta aagctataaa agatatttta aaagaagaaa aaactataaa
    31381 taaaaatgat ataacaagaa gattaaacag cattgggttt acagtatcaa gatttacagt
    31441 catacaatac ttaaaagaga ttcaagattc tggtgaccta aaacttgata aagagagtga
    31501 tgataaaaaa gaagaaataa tcaataatag agaaaataaa gatatagcat ttgataaact
    31561 tataggtagt agtggtagct taagtacaat tataaaacta gccaaagcag caattcttta
    31621 tccacctcat ggtcttcata ctattattat ggggccaact ggtgttggaa agagtgagtt
    31681 agcagagtgt atgtataaat ttgcagtaga atcatccaga ttccctaaga atgcaccatt
    31741 tatagttttt aatgcagcag attattcaga gaatccacag cttttgctat cacagttatt
    31801 tggacacgtt aaaggtgctt ttacaggagc tgatgagaac aaagaaggat tagtatcaaa
    31861 ggcagatgga ggaatattgt ttatagatga aatacataga ttacctcatg aaggtcaaga
    31921 aatactattt caactgattg ataaaggtat ggtcagaaag ttaggagaaa caagactaac
    31981 acataaaata gatgtaatga ttatttcagc aacttctgag ccaatagatt ctcatttact
    32041 taatacattt aaaagacgta tacctgtaac aattgaaata ccagaattag ttgcaagacc
    32101 attaaatgag aggtttgaca ttataaataa tttcttctta atagaagctc aaagaatggg
    32161 agcaaacata catataaagt cagatgtatt aaaagctctt atgctttacg attgtatagg
    32221 taatgtaggt caacttagaa gtgatattca agtagcttgt gctaggggac tattaaacca
    32281 acttacaaac aaactaaaag aagtaaatat aagcatatca gatgtacctg gatatgtaaa
    32341 acaaggtctt ataaaaatca gaaattgtag agggaaaata gaaaattatg tagatgggga
    32401 tttaattata gactcaaatc ttcaaggtga gatagaaaag aaaaatgaag atatatatac
    32461 ttttccagat gaaatataca aacttactga aagaagacat attgatttat tggaacaagg
    32521 tttagatttt gatgttataa atagaatcat tggaggagaa ttagaaagtt gcattcaaaa
    32581 atacataaaa caagttaaaa aagtttctat tagtaacaat cttccagata taagtccaat
    32641 tgttggaaaa tatatcgtag agctaactta tgaagtaatc aaaatagcat cacaatacct
    32701 aagttcacta gaaccgaatc tacatttatg tttagcagtt cacctaaaag cagcttttga
    32761 gagattaaaa gaaggaaaag taatatcaaa tgctcatttg aaagaaataa taggaaatta
    32821 tccagtagaa tattctgtag cagaaaaggt agctcaatat ttaaaggaaa gatataacat
    32881 aaacttacca aaagaagaaa taggtataat agcaatatat tttaaaatga gtagtagaag
    32941 agatatgtct gaacaaaaaa agataggcgt acttcttatg gctcacggaa gagtagcatc
    33001 ttctgtatgt gaggttacaa ataaactatt aggaattaat cacgcaaggt atttagatat
    33061 gccatttgag aagaagccgg aagaaatgat tgaagaagct actacaataa taaaagatat
    33121 tgatgaaggt agaggtgtga ttatattagt agatatgggt tcactttcat attttggaga
    33181 tattatttct ggaaagactg gaattaatat aaggacaata tctagatttg atacattgct
    33241 ttctatagag gttatacgaa gagcagtttt accagattta acaatagacg agatagttga
    33301 tgaagttaaa ggtatagagc cacaagtaaa agaaaaggtt agtaaatgta acaatacaaa
    33361 agtagatttt agaaaaccta taattttaac attatgtatt actggattag ggggagcttg
    33421 taagataaaa aaaatcttag aggaaaatat taaaagtata actgaaaagg ttgatataga
    33481 acctataggt atgattgaat atccaagtct tgatttagag ataaaacaaa taagcaatga
    33541 taaaaatgta atcgccatag ttggaacaat tgaccctcag atagcaaata tccctttttt
    33601 tagtctagta gacataaatg ataaagcgaa gttaaatcaa ataaataacc taattgatac
    33661 aaatcaaatt ggtgaaacaa ataaaaaata tgaattatca gatttaatac ataaagaaga
    33721 tatatttgtg gatttacagg ttaaatcaaa agaagaagtt ctaaaatata tgagtaaaaa
    33781 acttagagag aaaggttatg tgacaaaaaa tttctataaa aaagtagtgg aaagagataa
    33841 cttatttcca actgaattat cagatgaaat agcaatacct cacacagatg gaatagatgt
    33901 aattaggcca gctataagta tagccatctt aaagaagcct attgtgtgga gtaaaagtaa
    33961 agtaaaaata atacttttat tagctgtaga ccaaaagtgt tttaatccat taagcactct
    34021 actctcattt atagaaacag atgaatttaa gaagataaaa aacattaaag atagagattt
    34081 tattagggag atgatattag atggagtcaa tgaaaataat tagtagcaat ttaattttta
    34141 aaaatattga agtgtctaac aatgaagatg cattaaagtt tttgggacaa cgtttgtttg
    34201 acgaacagta tgtaaaagaa agttacatac aagctgttgt agcaagagaa aaaaagtatg
    34261 ctacagggtt accaacagaa atatacggag tggcaatacc acatacagat atagtacatg
    34321 taaatgagcc aggaatagca attggaatac tgaataaacc tgtaaaattt ataatgatgg
    34381 gtacagacga tactgaaatt gatgtaaaag ttgtatttat gttagcagtg aaagagccac
    34441 aagaacaatt gcaactatta gaaaaactta tgactatatt tcaagataag aatatactaa
    34501 ataatattgt tgacttaagt gaagaaagtg tgagtgattt attaaactct aaattgaaaa
    34561 attaaacatg taaagtatat taaaaatgta aaattaaaca tgcaaagtat gttaaaaaat
    34621 ataaaaagat tattaaagat ttctaactat agatatcttt aaaataaaat aatttcaatg
    34681 ggggtgacta atgtggctaa aaagatatta gttgcatgtg gaacaggagt atgtacttca
    34741 acaattgcta taaacaaatt aaagaaagca cttcaagaca ttggtaaatt ggatatggtt
    34801 aatattacac aatgtaaagt agtagaagtt gcatcaaaag cacctgatta tgatttaata
    34861 atttgtacta cacaagtatc tagtagtata aaaacaccag tgataaatgg attacctttt
    34921 ttaactggtg tcggaatgga taaattaatc aatgatgtat tagaagagtt agaattataa
    34981 ttaaaaaaat taaggaacat ggtctctaaa atcataagtt ttagagactt aaaattaaat
    35041 aatggagggt ctttatatgg agatattaaa tttcattgtt ggtctaggtg cacaagtaat
    35101 gatgccaata ataatatgta tttttggttt gatattaggt acaaaactag gaaaatcttt
    35161 aagagctggt ttaactgtgg gagttgggtt tataggtctt aacactatta tagctttgct
    35221 aacagataat ttaggtccag ctacacaaca aatggttaag aatttagggc taagtttatc
    35281 aataatagat gtaggatggc cagcagcatc agctatagct tttgcatcaa cagtaggggc
    35341 tttaattatt ccaataggtc ttgtggtaaa tatagttatg ctaattacta atactactca
    35401 aactgttgat gtagacatat gggattactg gcattttgct tttacaggag ctttagtggc
    35461 aggtgctact caaagtgtaa tgtggggagt atttgcatca gtagcaaata tggtaattgt
    35521 attggtaatg gcagatttaa ctgctccagg tatagaggaa tatttaggta tgccaggtat
    35581 atctcttcct catggattta cacaggcatt tgttccaatt gctatagtag taaataaatt
    35641 attagaccta ataccaggta taaataagat tgagataaat gctgatacat tgcagaaaaa
    35701 atttggatta tttggagaac ctttaataat ggggtctgta ataggtgtaa taattggtat
    35761 tgctgcgaaa tatgatataa aaggaatatt acaattaggt gtaactatgg gagctgtatt
    35821 aatattaatt ccaaagatgg cagcattatt aatggaagga ttattaccag tatcagaagc
    35881 tgcacaggaa tttattgaga agagatttaa aaacagaggc aagatttata taggcttaga
    35941 ttcagcagta ggaataggtc atcctgttac attatcagtt gcactagtgt tggttccttt
    36001 gactatactt atagcagcta tattgccagg aaataaagtt ttaccatttg cagatttagc
    36061 agtaattcca tttgcacttg tattaatcgt accaattaca aagggaaatg tgtttagaac
    36121 attaataata ggaataatta taattacttc tggattatta atcgcaacta acttagctcc
    36181 attatttacc caaatggctt taaatgctag ttttaaaatg cctgaaggag caactatgat
    36241 ttcaagtatt tgtgatggtg cgaatccatt aagttgggta tttgtaaaag ttatgaacta
    36301 taaagttatt ggaggagtag tttttggagt tatagcttta ggaatggcta tttacaatag
    36361 gaatagaata ataaatgaaa ataaaaagct atctatagaa gaataaggtt aaaacaattt
    36421 tattaaggag tgtataggtt atgaaaaaat ataaatatga ttctaaaaga tacttactca
    36481 gtgttacaat accaggattt tttatgattt taatattgat ttatgcactg tttaataact
    36541 atacaaattt taatttgaat atatatagtt tgttaataat tgtctgtact tatggtatat
    36601 tcaatacttt tatatcatca agtaatccta aaaaaattat tattgatagc aaatgtatac
    36661 attttacctc atttatgact acacataagt atgaaattaa agatatagaa aagataagaa
    36721 taagagaatt ttataataaa aaaatttatg taaaaattaa tgatggaaac ctttttaaag
    36781 gtaggtattg gataagaaca aatatgttta ataatagtat agcattatat agctatttca
    36841 ttgagttgga agagtgctta tatccagatt cactaaaatt tagaaataaa aaatttgaga
    36901 ataagaacat ataaaaataa aaaattgaat tgaagcctag cttaatcttt tttgataaga
    36961 tataagtttg aactttatac taaattttta gaattttcaa tcaagacaat aacataatag
    37021 ctaagcaatt agaacacaat taagatgtat aaggcatgta tatgatgaat gggaggattt
    37081 aattaatgtt attagagaaa ttaagaaaag aagtattaca agcatcttta gaccttttaa
    37141 actataattt agtgacatta acaggaggaa atgtaagtgg gagagatgaa caaactggct
    37201 atatagcaat caccccaagt ggaatggatt atagaaatct tacaccaagt gatattgtta
    37261 tagtagatgt agatggaaat attatagatg gaaaatggaa agcatcagtg gatttatcag
    37321 accacttgta tatatataag catagagaag acataaatag tataattcat acacattcta
    37381 catactcaag ttgttttgct attttaaatg aacctataga atgtgcaagt acaactcttg
    37441 caaatgaagt agggggttca gtaccagttg caaaattttc accaccaaca tctaaaaaga
    37501 tgggaaaatg tgttattgaa gcaattggtg acaaaagagc atgtctttta gcaaatcatg
    37561 gcgtaattgc agttggtcca tctgtaggac atgctcttac agccgctgta atgttagaag
    37621 attcagcaaa agtatattac ttagcaaaat caattggcac accagtgcta ctgcctgatg
    37681 aagaaattca aagagcgaga gatgtatttt ttaatgtcta tggtcaggat aaataaatta
    37741 gataaaattt taaaagtaat atgaaaatat agatattcaa tgatattaag gagatttata
    37801 atgatataat aagtttaata gttaagaagt aaaatatgaa atgtaatagt atataaattc
    37861 atttaagact aaaaagaata agataaaata aaaaggagtc tgtatttcta tgtattactt
    37921 attaaacaaa agcacaaatc cttactttaa tttggcatta gaagaatatc tatttttaaa
    37981 tgataaatat aatgatgata ttataatcat atggagaaat gaagaatcca tttttatagg
    38041 taaaaatcaa aatccatatc aggaagtata tcatgatgtt attgaaaagg gagaaattcc
    38101 tattttaaga agaatatctg gaggaggaac tgtttatcat gacttaggta atatcaatat
    38161 gtcattcata caaaaagata ggcaacttca tgagatagat tttttggagc atactaagtt
    38221 tatgcaaaag atgctttcaa ccttaggact agatgtatct ataactgaaa gaaaagattt
    38281 atttttaaat gggaaaaaaa tttcaggctc tgcacagtct ataaaaagaa aaaattctct
    38341 ttatcatgga actcttcttt acgattcaga tttaaataaa ttaactaaat atttaaattc
    38401 aaataaagca actgaatcaa atgcaactaa atctgtttca agtaaagtta caaatattaa
    38461 gtttttactc gaaaaagata taaattactt tttagattat tgtgttgaat atttaaaatc
    38521 taatataaag aatataaaag aacttgaatt ggatgaagaa gatattaaaa gtgtatacaa
    38581 tataggagaa gataaatata aaaagataga gtggacatat ggtaaaacgc cgaaatttca
    38641 agtagtgcta ccatttaata atgaaagtaa aataaatata catgttaaca gatggaaagt
    38701 atcaaaattt tttatttctt atgatgataa tgtaattaat atggacaagt tgttagattt
    38761 gaatttcttt aaagaagaaa taaaagagag tattttagaa aattatccac attacataga
    38821 tttaatcaat ttaatatttt aatataaaac ctctaatttg ataaaattgt cttatatcaa
    38881 actagaggtt tttaatattc ttgcatatta acaaccatta caaaattgta aaattaaaaa
    38941 caacactatt gaaaaatcaa tatatattgt aataaatata tgtgtttttc attagcaaat
    39001 agacattaac tatttataca actgaaaatt taatatataa ttaatcagat ggttaaaata
    39061 aaaatattaa aagttttaat aaatgatggt taaaaataaa atacgaggtg ataccatgta
    39121 tagtgttata attgttgcag cgggaagcgg aaggagaatg aacttagata taaacaaaca
    39181 gttcataaaa ttaagagaaa aagaaattat tgctcataca attcaagttt tttatgaaaa
    39241 tataaatata gatgaaatag tggtatgtat aaaaaaagaa gaagaagatt tttttaaaga
    39301 aaatataata aataagtata actttaaaaa tataaaaata gcatatggcg gaaaagaaag
    39361 acaggactca atatataatg gtttaaaaaa attagatgaa aattgtgata tagtacttat
    39421 ccatgatgga gcaagaccat ttgtcgacca tagaataatc aatgaatcta taaaggtagc
    39481 taaagaaaaa aaggctgtgg ttgtaggtgt tccagtaagt gatactataa agatagtgtc
    39541 agatggaaca gtacaagaaa ctccagaaag aaatttgctg tgggcagcac aaacccctca
    39601 aacctttgaa tataatctca taatagatgc ttatgaacaa gcatataaga acaattatta
    39661 tggtactgat gattcaatgt tggtagaaaa tataggtcaa agtgtcacta tggtaatggg
    39721 ttcttatgaa aacataaaaa taactagtcc agaagattta aatatagcag aacaaatatt
    39781 aaatatggaa aaaagagatg aagttaacag tagaaggaga attatatgag aataggatta
    39841 ggatatgatg tacacaaatt aacagaggat agaaaactta taatcggtgg tgtagagata
    39901 ccacacgata aaggtttgtt gggtcattct gatgctgatg tattgataca tgcaataatg
    39961 gattctattt taggtgctct agcattagga gatataggga agcatttccc agatacagat
    40021 gaagaatata agggagcaga tagtatgaaa ttattagaac atgtgtataa tctaataaca
    40081 agtaaaggat ataaaattgg taatatagac agtactataa ttgctcaaag ccctaagatg
    40141 gctccatata ttgagagtat gagaagtaat atatcaaaag ttttaaacac agacattgat
    40201 aatataaaca taaaggcaac aacagaagaa ggtcttggtt ttacaggagc aaaacaggga
    40261 atagcttcac aaagtatttg tttattattg ttgacaagtc agaataatta atatattatt
    40321 agtaataagt ttaatggata tcaagtaata ggcctatata gaatatctat aatgtatgaa
    40381 tttaagtgaa attaatataa atataaaatt agctatgata aagaaatagt aaaatgatga
    40441 aatcttcaca gagagaaaac ggtggtgaga gttttcaaga ggaagtcttt gaacctgtct
    40501 tttagcttaa aggtataaaa atctttacgg taggaaccgt tatattccca aaagagagct
    40561 attcatatag ctaactagag tggtaccgcg gaaattaaac ctttcgtctc tatacttgta
    40621 tagagatgag aggtttttta tattttcagg aagttaatat tcaggaggaa tctattaatg
    40681 aaaatgtcaa aaatgtttat gccgacatta aaagaaatcc cagcagatgc tgagattaca
    40741 agccatcaat taatggttag gtcaggcatg ataaaaaaaa tgacttcagg tgtttataac
    40801 caattaccaa tggggttaag agtgttcaaa aaaattgaac aaataattag agaagaatta
    40861 aataaaaaag attgtcaaga aatactttgt gcagccttac ttccttctga attatggaaa
    40921 gagtctggaa ggtggactgc tatgggtgaa gaaatgttta gactaaaaga cagaacagaa
    40981 agagagtact gtcttgggcc aacacatgaa gaagcattca ctgatataat aagacaagaa
    41041 attacttcat ataaacaatt gccactaaac ttgtaccaaa tacaagtaaa atatagagac
    41101 gagagaagac caagatttgg tgttatgaga actaagactt ttacaatgaa ggatgcatat
    41161 agttttgatg tagatgataa aggtttagat aagtcatatc aagatatgtt tgatgcatat
    41221 gtaagtatat ttgatagatg tggattggag aatagccctg tacaggcaga ttcaggagct
    41281 ataggaggtt ctacatcagc cgaatttatg gttaagtcag aagttggtga agatgaagtt
    41341 gtattttgta gtggatgtga ttatgcagcc aatgtagaaa gagcagaatc ttgtaatcta
    41401 gcatcacaaa aagaagaaat gaaagaatta gaagaggttc atacaccagg agcagctaca
    41461 ataaaagagt tagaagaatt tttaaaaact tctccagata agtttgctaa aactttagta
    41521 tatgaggcag atggaaaaac agttgtagtc gttgtaagag gagatagaga agttaatgaa
    41581 atcaaagtat ctaatgccat aggttctgtt atagaatttg ctcttgctac agatgatgta
    41641 gtgagaaaag taactaatgc agaagtagga tttgcaggtc caataggtat aaatgctgac
    41701 tatgtattta tagataaaga aattgttgaa caaagaaaca tagttgttgg ggctaataaa
    41761 actgagtacc atataaaaaa tgctaactat ggaagagatt ttgaaggaat agttggagat
    41821 tttagaaatg ttcaagaagg cgacaagtgt atagtatgtg gtaagccact tgaaatagct
    41881 agaggtgttg aagtaggaca tatatttaaa ctaggaacta agtactcaga atctatgaat
    41941 gcaaacttca tagacaaaga tggaaaatca aagcctatag taatgggatg ttatggaata
    42001 ggtgttgaaa gaacagcagc agctataatt gaacaacata atgatgagaa aggtataata
    42061 tggcctttgt cagtagctcc ataccatgtt gtgatagttc cagcaaatat gaaaaatgaa
    42121 gaacaaatat caatagctga aaatatatat aatgatttgc aagctatggg tgtagaagtt
    42181 ttattagatg acagagatga aagaataggt gtcaaattca atgattcaga attaatagga
    42241 atacctatga ggattacagt aggtaaaaat attaatgaag gtaaagtaga atttaaactt
    42301 agacataaag aagataaaga gataattgac atagaagaaa taaatgaaaa agtaaaggca
    42361 gagtttatca ggaataatgt taggttagga taataactta aataagatat tgtatagata
    42421 atcaaagttg tactttatag acaccatttt atctatatat aaggatataa aatggtgttt
    42481 ttttataaaa caaataaatg aggaggtaat taaaatggca aaaaatgaaa aacaatttgt
    42541 tgaagaaata acaaagatgg aagatgattt tccacaatgg tacacagatg taataactaa
    42601 gactgactta gttgattatg caccagtaaa aggttttatg gttgtaaagc catatggata
    42661 tgcattatgg gaaaagatgc aagaatttat ggataaaaaa tttaaagaaa ctggacataa
    42721 aaactgttat tttccattat taataccaga gagtttatta aacaaagaag cagaacacgt
    42781 tgaaggtttt gctccagaag ttgcatgggt aacacatgga ggaaataaaa aattagaaga
    42841 aagattatgt gtaagaccta cttcagagac tataatatgt acaatgtatg cgaaatggtt
    42901 aaaatcatat agagaattac catatcttta taatcaatgg tgctcagttg ttagatggga
    42961 aaaatcaact agacctttct taagaacatc tgagttttta tggcaagaag gtcatacgtt
    43021 acatgaaaca gcagaagaag cacaagaaga aacaatacaa caattagaag tatataaagc
    43081 gctatgtgaa gaattacttg caatgccagt tgtagctggt caaaaaagtg aaagtgaaaa
    43141 atttgcaggt ggtgaaagaa catatactat agaagctatg atgcatgatg gtaaagcatt
    43201 acaatcaggt acaagtcact tcctaggtca acactttact aaggcttttg atattacttt
    43261 tgcagataga gaaggaaatt tagctaatcc atatcataca tcttggggag catctacaag
    43321 acttataggt ggacttataa tgactcatag tgataacaga ggtttagtat taccaccaag
    43381 agtagctcca attcaagttg ttatagttcc tatagctgct aaaaaaggaa atgtaatgga
    43441 gactgttgat aaaatatatg ctgatttaaa agctaaggga gtagctgtag aagttgatga
    43501 tagagataac tatacaactg gatggaaatt taatgagtgg gaaatgaaag gtgttccagt
    43561 aagagttgaa attggaccaa aagatataga aaataatcaa gctatggtat ttagaagaga
    43621 tactttagaa aaggattcta tgcctttaga aggattagct gatgctatat gtgatttatt
    43681 tgatgttata cacaatgata tgtttgaaaa agcaagaaaa catagagaag acaatacatc
    43741 tatagttgaa aatatggatg agtttagaaa agctttagaa gaaaagccag gattcataaa
    43801 gactatgtgg tgtggagatg cagaatgtga agctaagatt aaggaagaaa caggagcaac
    43861 tataagatgc ttaccttttg aacaagaaaa cttaggtcac aagtgtgtgt actgtggaaa
    43921 agaagcagat agtatggtag taatggcaaa agcttactaa aatacattta aataaaaact
    43981 ggggtagaaa gtatttaata ctttatccca gtttttttgt tttttatgag taataaaatg
    44041 tatttgtaac tatgtcataa gataagtcat agatacttat attaaaaaga atataataga
    44101 gaactatttt taataattac atattaatga aagcaaaata tttttgttat atagattttc
    44161 aataaagcaa acaataaata taaatgaata ttagtaagga gtgcttttaa tttttagaaa
    44221 ataaatgact taaaagaaag atttatgaaa ttaaaactag gattttctga tataataaac
    44281 atgtgtattt ttaaataaaa aggatattat tattagattt gattaaaaat aaacttgcaa
    44341 aacaatgtac tagtttaata ttatagttat attgaataaa atatcaggag gaagtaaaaa
    44401 tgaatgtaag agtaaggttt gcaccaagtc caacaggatt tgtacatata ggtagtttga
    44461 gaactgcttt atataactat ttatttgcaa aaaaaatggg cggagaatat atattaagag
    44521 tggaagatac agaccaaagt agattagtag aaggtgctat agagaatatg cttaatgcta
    44581 tgaaatgggc tggggtcaac catagtgaag gtgttatatt agatgatagt ggaaaagtag
    44641 tacaaaaagg agaatatggt ccatatattc aatctcaaag attagatata taccaagaat
    44701 atataaagca acttttagat agtggaaaag cttattactg tttctgtaca aaagaaagac
    44761 tggatgaagt aagagatgct caaagagcag caggagaaac agctaaatat gatggtcatt
    44821 gtaagaatct ttctaaagaa gaagtagaag cgaatataaa agcaggaata ccatatgtta
    44881 taagattaag attgccagag aatcatacaa ttaagtttac agacttagtt agaggagata
    44941 tggaatttaa tactaatgac ttagatgacc aagtattaat gaaaacagat ggatttccaa
    45001 cttatcattt tgcagtagtt gttgatgact atttgatgaa aattacacat gttataagag
    45061 gagaagaatg ggtatcatct actccaaaac atgtttattt atatgaagct tttggatggg
    45121 aagcacctgt atttgtgcat ttaccaaata tacttaataa agaaaagaaa aaattaagta
    45181 aaagacaagg tgatgtagct gttgaagact ttaagaaaaa aggatattta ccagagggat
    45241 tagtaaacta tgtagcatta gttggttggt ctcctgaaga taatcaagaa ttgtttacaa
    45301 tggaggaatt agaaaaagcc ttctctgtag aaagagtctc taaaagtggt ggagtatttg
    45361 atactgaaaa attaaattgg gttaatcagc attatataaa agatggtgat gatgcttatc
    45421 taacagactt agcaatacca tttttaatag aagatggatt tataacagaa gaagaagcta
    45481 ctaataaata tgatttctta aagagtatga tatcagtact taaagagaaa ttacaatatg
    45541 taaaagaagt tactgaacat gcaagtatat tttttggaga taaaatagag gtagaaactg
    45601 aagagggaag agagttctta agattagaac atatacctac tttaatagat gctttgagag
    45661 aaaaaataga aaaaacagag gtattaaatg ctgagtttgt tcaagctatg cttaaagaaa
    45721 tacaaaaaga gtacaaaata aaagggaaaa atttatttat gggctcaaga ataattttga
    45781 cagggcaaat gcatggtcca gatttaccaa aagtaatgga agttttagga aaagaaactt
    45841 gcttaaatag aatagcttat gtaaaaaata atatattata gtcataaaag tccgctaatt
    45901 tagaagcgga ctttttttgt gttagtattt ggtgaaaata tctgcttaag aaaatgaagg
    45961 tatttaaggt aataaattta atatataaaa agcaaagcaa aaatataaat aaaatatgaa
    46021 taataaacta ataaaatatt aagcatagaa gaagggaatc tattatttta gtttgattta
    46081 attattaagg gggtaattac tatgtatagt aatattgatg atgttaaaaa ggaattaaag
    46141 gagctatgct tagaatatgt tacaatttta gaaaaattaa aagatgaaaa aatgattaca
    46201 gaagaaactt ttgaaaagtg ctcttctcaa aaaaaaatat ttttagaaga acaatagagg
    46261 atggtaatag tattattatt atgtagtttg aaagatagta cgaaaaatga tagtaatact
    46321 attatttatt gcaattttca actataatat aatatataat gttaagaaga taatttataa
    46381 aaatacagtg aggtgatgag tgtgaaagtt tataatacat tgactagaac aaaagaagaa
    46441 tttgttccat tagaagaagg aaaggtaaaa atgtatgtgt gtggtccaac agtttataac
    46501 tatatacaca taggtaatgc aagaccattt ataatatttg atactctaag aaggtattta
    46561 gagtatagag gatatgatgt aacttatgta caaaacttta cagatgttga tgataagatt
    46621 ataaatagaa gtcatgagga gggaatatct cctgaagaag ttgcggctaa gtatataaaa
    46681 gaatattttg tagactgtga tgggctagga ataaaaagag ctactgttca tcctcaggtt
    46741 acagataata tacaacagat tatagagttt ataaaagagt tggaagataa gggatatgca
    46801 tatgcagtaa atggtgatgt atattttgat acaaataagt ttgaaggtta tggaaaactt
    46861 tcaggtcaaa aacaagaaga tttagaggca ggggctagaa ttgaggttaa tgaccaaaaa
    46921 agacatccta tggactttgt tctttggaag gcaaaaaaag aaggtgagcc aggatgggat
    46981 agcccttggg gagaaggtag accaggatgg catatagaat gttctgttat gtctaagaga
    47041 tatttaggtg aaacaattga tatacatgca ggtgggcaag atttaacatt cccacatcat
    47101 gaaaatgaaa tagctcaaag tgaagctaga agtggaaaaa cattctcaaa atactggatg
    47161 cataatggat atataaatat aaatgatgaa aagatgagta aatcaaaagg taatttcttt
    47221 acagtaagag atatatcaaa attatatgat ttagagatag taagattttt catgttatca
    47281 gcacattata gaaatccagt aaactttagt gatgagatgt taaatcaagc taaagcaggt
    47341 cttgaaagac tatataatac taaagaaaaa ttagaattta cgctaagtaa tttagtagaa
    47401 tctcctttaa cagaaaaaga agtagagctt gttaaagaat tagatgactt tagacaaaaa
    47461 ttcatagatg ctatggatga tgatgttaat acagcagacg cagtaagtgt aatatttgaa
    47521 ttagctaagt taataaattc taatgtagat gaaaattctt ctttggagtt tgctaaaaaa
    47581 tgcttagatg aatttaatga acttacagga gtattaaata ttgtaaataa gaaaaaagat
    47641 actgtattag ataaagacat tgaagaattg atacaaaaaa gaactgatgc aaagaaaaat
    47701 aaagagtttc aattagctga tgatattaga caacaattac tagatatggg aattgtatta
    47761 gaagacacaa gacaaggtgt taagtggaaa aggatataaa aatggaaaaa actgaattag
    47821 ttactatgtc accattagtt ttagcatact taggtgatac agtgtatgag acatatataa
    47881 gagaatattt aattagacag aatacacaaa gaaaagttaa tgatttgcat aaactagcta
    47941 taaagtatgt aaaagctaaa gctcaggcaa ctataattca tgaaattgaa attgagttaa
    48001 ctgaagaaga gagtaaaatt tataaaaggg gaagaaatca aaagtcaaat acttctccta
    48061 agaatgcaga tattatagac tacaaacatg caactgggtt tgaggcatta gtgggatatt
    48121 tgtatttaaa taatgaaata gagagacttc aatatattat caataaagga atcaaaatta
    48181 ttgaaagaga tatgtaaata ttaaagagtg ttgtcttaat aataagtaat aaggcaacac
    48241 tttttttata actaatgtat aataaatata tagaaattag taatgagaaa ggataaaaag
    48301 ttatgaaagt aaaattaata tcacatacac ctgaaccaga aaaagtaata gctatggcag
    48361 ctaagctatg ttattcacca gttgggacag acgaaataga aaaagactta acagatgaaa
    48421 gtatagagaa atttttaaat atgttattaa gtataggtca tgggtcaata ttagaacatg
    48481 cttcatttac attttcaata gaaggtattt caagggcttg ttcacatcaa attgttagac
    48541 atcgtatagc tagtttttca caacaaagtc aaagatatgt taaattagaa caatttgagt
    48601 acataattcc tccagaaata gaaaaaatag aaaaggcaaa agagttattt atagactcca
    48661 tgaaaaaaga ccaagagaat tatgataagt tagttgaaat attgtttgaa aatcattata
    48721 atgacctaat aaaaaacggt aaaaatgaga aaacagctaa aagacaagct gaaaagaaag
    48781 caatagaaga tgctagatac gtatttccaa atgcatgtga aacaaaaatg gtatttacta
    48841 taaatgctag aagtttgttt aatttctttg aacatagatg ctgtgaaaga gcacagtggg
    48901 aaataagaaa tttagctgtg gagatgttaa gagaggttaa aaaggttgct cctatattat
    48961 ttaaaaagac cggtccaagt tgtgtaaatg gaagttgtcc agaaggaact atgacttgtg
    49021 gagatatagt tcaagttaga gaaaaattta aggccttgta ggaggtgaat aatttggcga
    49081 gtatagaagg aagaaatccg gtaatagaag caataaaaag cgacagagaa atagataaaa
    49141 tattaattgc aaattcagct aaagaaggtt caattaagaa aataatagga atggctaaag
    49201 ataagaatat aattattcag tatgttgata aacataagct agatgaagta agtacaagtc
    49261 attcacatca aggtgtaata gcttatgcaa gtgagtataa gtattatgaa ttagatgagc
    49321 taatagattt agcaaagaat aaagatgaag acccattttt cattatatta gatgagataa
    49381 cagacccaca taatttgggt tcaataataa ggacagcaga tgcagtagga gcacatggag
    49441 ttatcattcc aaaaagaagg tctgtacaca taactcctgt agttgccaaa gcatctgctg
    49501 gagcagtaga atatatgcca gtttgcaagg taaccaatat agttaataca ataaaaagac
    49561 tcaaagaaga agggctgtgg attgctgcag ctgatatgga tggagaaact ttttataaac
    49621 aaaatcttac tggtcctctt ggtgtagtaa ttggaagtga aggttttgga atatctagat
    49681 tggttaaaca aaactgtgac tttatagtaa aaatgccaat gataggtaat gttacatctt
    49741 taaatgcatc tgtagcaggt ggaatacttt tatatgagat attcagacaa agactggata
    49801 aaagtaaata ggcatgaaaa aaaatataaa tcattactta ataatagatg gctacaatat
    49861 tataaatgcg tgggacaatt tgaaagaact ggctaaagag gacttagaag attctcgaga
    49921 aaagcttatt gatgacatta tagaattttc tgagtttatg ggttataaga ctataatagt
    49981 ttttgatgct tataatgtta aaaattctcg agaaaaagtt gaaaaaagaa aacacataac
    50041 aatagtttat acaagagaac accaaacagc agatagttat atagagaaat ttataacttc
    50101 tttatcaaag tatgatgatg taaaagtagc cactaatgac tatgcagaac agcaaatgat
    50161 tttaggaaaa ggtgctacta gaatgtctgc aagagaatta aagttagagt tagatcgttc
    50221 caagaataaa atgaaggaaa aaaatatcgg tttgaggaaa aaaattcagc gaaattggtt
    50281 ggaggaaagg ttagataaag aaacattgtc gaaacttgag aacattcgta gaaagcgttg
    50341 aaattactag gttctttaga ctataatata cctataaatt tgttttatat atgggggaga
    50401 tttacatgtt ggtagcaaaa gaaaaaagtt atgagttagt ggacaattgt cagcaggatg
    50461 agtataacat tgtattaaga gcaagtgaag gggataaaat agcactagag tacattatta
    50521 ctaaatacag aaattttgta aaggcaaaag caaagtcata ttttttaatt ggagcagata
    50581 aagaagatat aatacaagaa ggaatgatag gcctttataa ggcagttaga gattttgatg
    50641 gaagtaagac caattcattt aaatgttttg cggagatatg tataacaaga caaataataa
    50701 ctgctataaa aactgcaaca agacaaaaac atataccttt aaattcatat gtttctttga
    50761 ataaaccaat atatgatgaa gagtcagaca gaacactttt agatattata gctacaagta
    50821 tagtaacaga tccagaagag cttataatta gtaaagaaga gttaaaaaat atagaatcaa
    50881 aaatgaacga attgttaagt gacttggaat tagaagtact agaattatat ttaaatggaa
    50941 agtcatacca gtttatagcg gacaagctta aaagagatgt aaagtcaata gataacgctt
    51001 tacaaagggt taagagaaaa ttagaaaaac atcttgaaaa cagaaatgat taatagtaaa
    51061 atacttacca taagcttatt gtgagcaaaa ttaatttata tcgaaagata agggaggaaa
    51121 ttcaaaatgg ctaaagctaa atacgaaaga acaaaacctc atgttaatat agggacaata
    51181 ggacacgtag accacggtaa aactacatta acagcagcaa taacaaaaac attatatgac
    51241 agatatcaat taggagaagc agtagatttc gcaaacatag ataaagctcc agaagaaaga
    51301 gaaagaggaa tcacaatatc aacagcacac gttgagtatg aaacaccaaa tagacactat
    51361 gcacacgttg actgcccagg acatgctgac tacgttaaga acatgataac aggagcagca
    51421 caaatggatg gagcaatatt agtttgttca gcaacagatg g
//
LOCUS       DAEPKC010000017        51211 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.017, whole genome shotgun sequence.
ACCESSION   DAEPKC010000017 DAEPKC010000000
VERSION     DAEPKC010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 51211)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51211)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51211
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.017"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..771
                     /locus_tag="KR294_001103"
     CDS             <1..771
                     /locus_tag="KR294_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide polymerase"
                     /protein_id="HBH0239191.1"
                     /translation="SLIFNQEVHYRYIEKIDMLVTRMDFGLGNPNSVFYHMVTIYAAY
                     IFLRYKDYNKWDRIILFGSAFFVYQTTYSRTGFFTILAGLIFVEIIRWIDIKKIKGLP
                     MLLKTLPIILTLFSVIIGTVFDKSTLLNRLLASRPKFWHVYLAEKGNFLKPFGNSYSP
                     AIKATNPLDSSYVYIISVLGVVACILFMYLMYKGIESFIEKDKKAYLVALFIFLLYSF
                     AENLLLEASFSFAVVLLIKEVILNDKREIDLWKMKSRR"
     gene            774..1613
                     /locus_tag="KR294_001104"
     CDS             774..1613
                     /locus_tag="KR294_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBH0239192.1"
                     /translation="MLISLIMPTLNRYDDIYLLMDSLENQTYKNFELIVVDQNDNSKV
                     KEIVDKYIDKLDIKYIKSSKKGLSYNRNVGIDNAVGQIIGFPDDDCVYENDTLEKVIN
                     FFNKNKDYKIYSCKTMDSNKVDAFKKMYDGTCDITSSNVLDTITSITFFIDFEGKDYT
                     RFDEKLGVGGEFGAGEEIDYVLNLLSLGFKGKYFGNDIIYHPAKKHSKSKEKYQKDYN
                     YGRGFGALCKKEIVYRKNYKFAKVMVSKLVRNIGGLILSSNRDYHSATIKGRINGFRQ
                     YKL"
     gene            1628..2803
                     /locus_tag="KR294_001105"
     CDS             1628..2803
                     /locus_tag="KR294_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-glycerol glycerophosphotransferase family
                     protein"
                     /protein_id="HBH0239193.1"
                     /translation="MDKVKFLINMLLAFFIYPFNKHKFNGRNIWLIGGHSGDIYNDNS
                     KFFYEYMLKEHNDVETYWVVNKDSKVFDKIPGKKLIRGSVENYLYYYNSKAIVFSHAP
                     SADIAPYNFAVPVLNYFHKKTIKVFLNHGTISFKKRKPMNKKFKNIIDNLYKSYNIVT
                     ASSEFERNVMVNDWGMLDDSVYIIGNARYDNLPTNEVAQTRDILYTPTWRDWIKFSSG
                     KFTDTDYFKNIMNFLNDDKLNKILDEKDINVKIYMHHLMHEFIDDIKENITGKRIVFL
                     DKGVTLANEIRKSAANITDYSSVAIDFLYMNRPILFYQFDLDEYMEKVDSYIDLKSEM
                     FGSLAYNNDEAVNKLIDIIENNFEVMDNQKNERNKFFRYNDNKNCKRIYDCVLSKIK"
     gene            2832..3581
                     /locus_tag="KR294_001106"
     CDS             2832..3581
                     /locus_tag="KR294_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBH0239194.1"
                     /translation="MKKNLVSIITPMYNSEKFIEATIKSVLNQTYQEWEMLIIDDCST
                     DNSPNIVKSYMQQDSRIKCIKTETNKGVSNARNLALSKATGQFIAFLDSDDQWNSSKL
                     EKQVNFMLENDYVISFTSYELMDENDKKLNKVIKVPPNVDYRRLLKGNILGCLTVVID
                     KSKLDFEIRMSGVRHEDYVLWLSILKKGHIAHGINEVLALYRKSSNSLSGNKIKAAMW
                     TWNIYRNIEKIPLYKAIYYFINYGINGIKKS"
     gene            3603..4511
                     /locus_tag="KR294_001107"
     CDS             3603..4511
                     /locus_tag="KR294_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBH0239195.1"
                     /translation="MYKYKFTVFTPTYNRAHLLENLYNDLKAQTYDFNDFEWLIVDDG
                     SSDSTKELVEKFISENKLNIRYIYKENGGKHTAINLGVKNADGELFFIVDSDDGLIKD
                     SLEIANDEWDSLENKEGFSGVVGLCVYPSGDLIGTEMPEDKKICHFADLYFKYGVKGD
                     KSIVFVTDELIKFPFPERKEVRFLPESVVWNEMSKYYKVICVNKPMIIRDYLDDGLTK
                     NILSKNALRGRALEFLYLINQNTYPLSRYPYMWIKNYINLARYSLLSDSHYFGELRKV
                     SDKLLYLALFPLGYYKYIGQRKLVSK"
     gene            4559..5311
                     /locus_tag="KR294_001108"
     CDS             4559..5311
                     /locus_tag="KR294_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBH0239196.1"
                     /translation="MNEPLVSIITPVYNSEEFLSETIKSIQNQTYKNWQLLLVDDCSK
                     DNSSEIIKSFRKEDARIKYIKLEKNSGAAVSRNVGIKNAEGRFIAFVDSDDLWDSRKL
                     EIQIEYMLKENVGFSFTSYRYMRQDGSKTNKVARAPKKIDYEGLLRNTIIGCSTVVID
                     KEIVGEFSMPLVRRGQDTATWLQLLKKEKYAYGIQEDLVNYRLVGNSISSNKIKALKR
                     TWNTYRNVENLSLPKSLYVFCFYVFNAIKKRV"
     gene            5265..6632
                     /locus_tag="KR294_001109"
     CDS             5265..6632
                     /locus_tag="KR294_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose/GDP-mannose dehydrogenase family
                     protein"
                     /protein_id="HBH0239197.1"
                     /translation="MYFVSMFLMPLKKEYKFYILGGKKMKIAIAGTGYVGLVTGVCLA
                     EVGNENVVCVDVDEQKVKSMKLGIAPIYEEGLEELMVKNYNRGRIDYTTDYKKAYEDV
                     DVILIAVGTPERSDGSANLDYIKAVAKQIAETVTKDTLVVIKSTVPIGTNEEIEDYIN
                     RNLKNDVKVELASNPEFLSQGTAVKDTLHASRIVIGVESEWAREILEEIYKPFNQPII
                     VTNRNSAEMIKYASNNFLALKISFMNDIANLCEIAGANIEDVALGMSYDDRIGSKFLK
                     AGIGYGGSCFPKDTKALHWLSEHNGYELKTVKAAIEVNESQKLKLVRKASKLVESFQD
                     MKVAVLGLTFKPDTDDIREAPSIPNIKYLLERGARVTVYDPIGVNNTKKIFGDSILYA
                     DSVDDAIEDAEICFIMTEWKDVLNYDIHKYKEKMKNPLVLDGRNCYKIKDMEELGIEY
                     YSIGR"
     gene            6638..7729
                     /locus_tag="KR294_001110"
     CDS             6638..7729
                     /locus_tag="KR294_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBH0239198.1"
                     /translation="MKTVCYLADGSNPHTLKWCSFFKNKGYDIHVISLNGGHMEGIKI
                     YNFGSNVEELKNENISKKTGYLGSIKQIKKLVNEIKPDILHAQYASSYGFIGSLLGYH
                     PYIISVWGTDIYDFPNNGFIQKQIIKHNFRKADYIFSNSRDMAKEANKYTAKHVDVTF
                     FGVDMDRFKPMEVEKEDAFVIGIIKSLEKKYGIEYLIQAFKMLKDEYKDKKIILKIGG
                     SGSQMDNLINLAKELGIENDVQFLGRISPENVSKTFNSFDVTVFPSLREGFGVAAIES
                     EACEVPVIVTNVGGHPESVWENETGLIVEPKQPEEIKNAIIKLMENDELRLNMGKKGR
                     QFVRENYEVNLNFNDIEKIYDSIFDKYKK"
     gene            7813..9726
                     /locus_tag="KR294_001111"
     CDS             7813..9726
                     /locus_tag="KR294_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBH0239199.1"
                     /translation="MRESIDLEKESFFNRLFKKYKFRHLTLLILDICSVLVAFRMSLS
                     LTGNLNAFTTNDIIISACIYIVLHIVSFRLFKCYNTLWRYAGEEEIISIFMATLAYLI
                     PIYIINKLLGFDYPIMFYVLNTIFIIMFTSGARIAYRAIRIVMNKTYSRGKVSNILII
                     GAGDAGEMVIQELKRNPELKKVAVAIIDDDKNKIGRIIHNVKIVGTTSDIKDVVEKYN
                     VDEIIFSIANIEKRRKKDIIDICKNTNCKIKTIPGIYEIIDGKVDIKQIREVEIEDLL
                     GREPIKTNLREISNYIEGKVILITGGGGSIGSELCRQIAGFNPKELIIVDNYENNAYS
                     IQQELLRKYKNKLDLKTVIASIREEKRMDEIFNKYKPEVVFHAAAHKHVPLMESSPGE
                     AIKNNIFGTLNIAGLSSKYRAKKFVLISTDKAVNPTNIMGATKRAAEMIIQTMNAESQ
                     TEFVAVRFGNVLGSNGSVIPLFKKQIEDGGPVTVTHPDIIRYFMTIPEAVGLVIQAGA
                     MAKGGEIFVLDMGEPVRILDLAKNLIKFSGFEPDVDIKIEFSGLRPGEKLYEELLMSE
                     EGLLDTEHKKIFIGRPIDVDREKITKYLKLLREITNNEEVEKIDGIMRELVPTYIKPE
                     DANIKEIATTREK"
     gene            9925..10632
                     /locus_tag="KR294_001112"
     CDS             9925..10632
                     /locus_tag="KR294_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBH0239200.1"
                     /translation="MMNIKNKKHILKKFIAMVLIAGVVTVEAGAITASAAEPTNSPMS
                     ATVDQCDFLNVRSGASANDAVVGKINTGDKVEVLELHSNGWIKIKSVDNVTGWVNGDY
                     LTIQGGNVDAKVQNVLNLAFKQQGKPYKWGATGPNSFDCSGFTSYVYKNGAGVNLPRV
                     SRSQATVGKKVSRAELKPGDLVFFGSGGSINHVGLYVGDSKFIHSPQTGDVVKVTSMA
                     PGTNYARRLITATRVLQ"
     gene            10934..13045
                     /locus_tag="KR294_001113"
     CDS             10934..13045
                     /locus_tag="KR294_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding glycosyl-hydrolase Cwp19"
                     /protein_id="HBH0239201.1"
                     /translation="MKKISILVLSLIMTLTMCSVSSFADSSNDKEMRAAWISTVYNLD
                     WPKTKNNEAKQKKEYTDLLDKLKSVGINTAVVQVRPKSDALYKSNINPWSEYLTGTQG
                     KDPGYDPLPFLIEEAHKRGMEFHAWFNPYRITMADESIDKLPANHPAKKNPSWVVKHG
                     NKYYYDPGLPEVRKYIVDSIAEVVQNYDIDGVHFDDYFYPGVSFNDTATYQKYGKGQN
                     KDDWRRENVNTLLRDVKASIKSIKPNVVFGVSPAGIWRNKSSDPTGSDTSGNESYVGT
                     YADTRAWIKQGLIDYVVPQLYWPIGLKAADYSKLVAWWANEVKGTNVDLYIGQGIYKQ
                     GQSSYGGQNIAKEIVQQVTLNRKYSEIKGSMYFSAKDIANSTSIQKDLKSLYSSSEEP
                     VTPPSNVKVEKLRGDERYDTAVAISKKGWATNSDTVVLVNGYSIVDGITSTPLATSND
                     APILLVNKDNIPTSTKNELKRLNPSKVILIGGNNSIGDKVESEIKDTLSNVSINRVGG
                     SDRYSTSLMIAKELVKTNPVEKLYITSGTGEADSLSIASKAGEEKQPIVLVSKDNVSD
                     EVYNWISDLKVKDAYFIGGNLSISDSVINKLDKVITNDVSKNRIAGENREETNGKVIQ
                     KFYLNAEYSSMFVSKSNQLVDALTSGPLAAKLKSPVVMLGNSVTSAQKTALEPKKTTL
                     VYEAGDGINQNTLNTFLNLVK"
     gene            complement(13243..14208)
                     /locus_tag="KR294_001114"
     CDS             complement(13243..14208)
                     /locus_tag="KR294_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBH0239202.1"
                     /translation="MSKLKKFVILLAFLVVIFPISVYGYFYYKLSAIHDSSISSDLLD
                     NNDHKNEDGIINILLMGTDARPNEDSSRSDAMMILTIDNKHNDIKLTSLARDSYVDIP
                     GHGKQKLTHAYAYGQADLLIQTIEENFNIDIQNYACVNFESFMYIIDAIGGVEVTVEK
                     GEIRELNKFIPETYKWNKSDDKGSIQYIRNSGKQTLNGYQALSFARIRHNDTAFARDG
                     RQRQIIQAIIKKTETLPVTKYPGLLDAVLPYVKTNMKPNAILSLGAQVLKMGDLNIKQ
                     FEFPIDDEIHSTGGIYGKAGWVLRFDPDTLDILHDFIFNDIEFKQ"
     gene            complement(14494..15450)
                     /locus_tag="KR294_001115"
     CDS             complement(14494..15450)
                     /locus_tag="KR294_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBH0239203.1"
                     /translation="MSGLKKFVIFLALLVIAFPVSIYGYVFTKLKTIQDDSINTEALS
                     SNDYKNEENITNILLLGTDARPGEEVSRSDAMMILTIDNKNKSLKLTSLNRDTYVNIP
                     GRGEQKLTHAYVYGQANLLIETIEENFQLDIQNYAVVDFFSFMDIVDALGGVTVTVDK
                     SEIRELNKFIPETYKWNKNDNKGSLKYIRNSGEQKLNGYQTLAFSRIRKNDSTDERDR
                     RQRSVIQSLINGVKDLPVTKYPNLVNTILPYVKTNMNPNEIISLGKELLSIGNLNLKS
                     MEFPLSTENGRKIGNAGYVIPFEEYELDAMHDFIFKDIMVED"
     gene            15818..16606
                     /locus_tag="KR294_001116"
     CDS             15818..16606
                     /locus_tag="KR294_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBH0239204.1"
                     /translation="MIKLIATDLDGTLLDEKSEINPEFYKVFKKLRERGIMFSAASGR
                     QYQNLIKKFEDIKDDMMFISENGTLVVYKGKEILSNPLNKELVNEIIETTRSIKGKKI
                     VMSGKKYAYIESKDEAFIQEVSTYYAKFKIVEDLTKVEGDILKIAVFDFKGAEHNNNI
                     YFEKFSDRAQVCISGVEWLDLTAKGANKGSAIKKVQKMLDIKYEETMVFGDQLNDVEM
                     MKSAYHSYAMENANEHLKQIARFRAKRNTENGVVDKIKEVIKIG"
     gene            complement(16729..17199)
                     /locus_tag="KR294_001117"
     CDS             complement(16729..17199)
                     /locus_tag="KR294_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4358 domain-containing protein"
                     /protein_id="HBH0239205.1"
                     /translation="MKKILILFFSIILSLGMVSCSSSGDYKNVSTSKIKKALKSSDLL
                     IKESKIFDAKDFNYFNDVEEDIIQGFVINSSEKLSLEDIIVIKTDEVDKIYKTLENYK
                     KDMIQAPFGEGHGEKINSEIANNTIIEKAGRYVYLISAENATQIENKILNIIKK"
     gene            17338..17982
                     /gene="uppS"
                     /locus_tag="KR294_001118"
     CDS             17338..17982
                     /gene="uppS"
                     /locus_tag="KR294_001118"
                     /EC_number="2.5.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="di-trans,poly-cis-decaprenylcistransferase"
                     /protein_id="HBH0239206.1"
                     /translation="MRIPKHVGIIPDGNRRWASQNGMTKDKGYESGIDPGLESYRLCR
                     DLGCEEVTFYGFTTDNTRRPSVQTKAFTKACIDAANILIDEGAALLVVGNTKSPMFPE
                     ELLPYTNRIKAKEGQIKANLLVNYGWYWDLNNISGVENVNKNNIQDYIQSFDVSRLDL
                     IIRWGGRRRLSGFLPVQSIYADFYVIDNYWPDFKSDDIKDAFSWYDTQDVTLGG"
     gene            18025..18930
                     /locus_tag="KR294_001119"
     CDS             18025..18930
                     /locus_tag="KR294_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBH0239207.1"
                     /translation="MKKKLLDGKITLIICKSVKIYTKKGEEMSKGNNNNNSRNKSKKT
                     SHLNRKKRKLNKKKLAVLICFTVLFLFIAFKATQGVVALVKSMDKSNKTNQQQNVNSE
                     QFDLGNEEENKKKKYTVFIDPGHGGNDKGTESKTSNRYEKDLNLQIAKKLANKLSKQK
                     DIQVVVSRTDDTYISLKDRAILANNSSADVLVSIHLNAEKNGNTATGIETWYRNKATD
                     GSKELAQTVQSTIVSYVKVRDRGIVENNFEVLRESNMPAILIECGFLTTPSEEQKIIN
                     EKYQDQLAEGIVQGVLSYLDSKGNK"
     gene            19245..20792
                     /locus_tag="KR294_001120"
     CDS             19245..20792
                     /locus_tag="KR294_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBH0239208.1"
                     /translation="MNKNSMTKIYSLNKIIFIIIGILGIVLLTRHIEVDIKVLILILL
                     TLFSINVFISYLKIKLYEDKINLGLINNSDKFINITKDENFLKHVQNYIISNEKENCV
                     MACFDLCRLKLINDIYGYELGDEVLNNILSNLKNYFGKEAIYGKLKSDVFVLIIKLEN
                     REQKIPYLVNLIKNKIVILSQIDSFKMDINIEASIGIYKFNNNEIDIKKAIDNADMAR
                     LKSKGLKHIEYVEFDNAMEEEIQSIMKIERDLFLAIKNKEFVIHYQPKVDSSTGNIIG
                     SEALIRWLHPSLGMVGPNKFIPIAEKNGLINNIGRWLIQEVFITINKWISEGINVLPV
                     SINLSRVELYKNDLVDFFKLMFNTYNIPKELIELEITETTALRDVKFISERLYEIKSL
                     GMNISLDDFGVGNSNFINLKGIPLDIIKIDRSLILDIVTNTKTKFMVKAIVNLSHDLN
                     VTVICEGVEDMHQVKVLSELGCNFIQGYVFFKPLDEMNYKKLLTDGSYINLKDTLLDK
                     CMTVEEE"
     gene            20795..21193
                     /locus_tag="KR294_001121"
     CDS             20795..21193
                     /locus_tag="KR294_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HBH0239209.1"
                     /translation="MISEDVDYSIRIIRAIFNNGEDKPIDAKMILKSEDIPILTLYRL
                     LRKLCANNILTFNKEDGKTYMLNVSLDTISLRTIVEVIDGKIYINKCTRYVSNCSNCL
                     KGCKVNRELLEIEKEIYKLLSRKSIRQILE"
     gene            21233..22966
                     /locus_tag="KR294_001122"
     CDS             21233..22966
                     /locus_tag="KR294_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
                     /protein_id="HBH0239210.1"
                     /translation="MDDISQDNFLLSKEYENSLDVDTKKASGIYYTPKIIVDYIVKKT
                     LKNHDIIKNPYPRILDISCGCGNFLLEVYDILYDLFEENIYELKKKYDENYWTVDNIH
                     RHILNYCIYGADIDEKAISILKDSLTNKKVVNDLDESDIKINLFCCDSLKKKWRYKFD
                     YIVGNPPYIGHKKLEKKYKKFLLEKYSEVYKDKADLYFCFYKKIIDILKQGGIGSVIT
                     PRYFLESLSGKDLREYIKSNVNVQEIVDFLGANIFKNIGVSSCILTFDKKKTKETYID
                     VFKIKNEDICINKFETLEELLKSSKFEHFNINQRLLSDEWILVNKDDETFYNKIQEKC
                     KYSLEDIAISFQGIITGCDKAFILSKDDVKLNLVDDKFLKCWIKSKNINKYIVDKSEY
                     RLIYSNDIDNENTNKRILDEIIGLYKTKLENRRECKSGIRKWYELQWGREKLFFERKK
                     IMYPYKSNENRFAIDYDNNFSSADVYSFFIKEEYLDKFSYEYLVGILNSSVYDKYFKI
                     TAKKMSKNIYDYYPNKVMKIRIFRDNNYEEIENLSKQIISILLNKSIDKGKVEKLQIK
                     MDNLIMDSLGI"
     gene            23198..24409
                     /locus_tag="KR294_001123"
     CDS             23198..24409
                     /locus_tag="KR294_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HBH0239211.1"
                     /translation="MKGLVLEGGGTKGAYQIGAYKALRELGIEFQGVTGTSIGALNGA
                     YIIQNDIEVMEDIWLNYDYTHFMNIDRETYERFKNVDFTTKNLNAVFELINKARKNEG
                     IDISPLRQLMETTLNEDIIRKSKKDFGLVTVWWDKKINPYPLYIEDIPKGRLIDYLIA
                     SSSLPIFQTNMMDDKLYLDGMFCDNMPIGLLEDKGYEDVVVIRLIDDFIGKMNLNRHQ
                     NINIKTIIPSEYLGGSLNKDRDNVEKNIRLGYLDTMKAYERCTGIKYYFDVEYKYNEE
                     YCFDKFRSMSNETIQYICNLLNIKRDASLRTVMESVIPKLGEVLGLPKDFSYKDLFYC
                     IYEKKLEENNINRIKLYDFNKVIDVVNTNIDSNRNLASNFEVRPKISIKKNKNTKLLT
                     NCIIKDIKNQS"
     gene            24602..24862
                     /locus_tag="KR294_001124"
     CDS             24602..24862
                     /locus_tag="KR294_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr family phosphocarrier protein"
                     /protein_id="HBH0239212.1"
                     /translation="MEKVVSIKNASGLHARPAGMFVKKAAEFKSTVEVVAKDKTVNAK
                     SIMGIMSLGLAQGEELKLVVNGEDEEVALAAMVELVESGFGE"
     gene            25215..26927
                     /gene="ptsP"
                     /locus_tag="KR294_001125"
     CDS             25215..26927
                     /gene="ptsP"
                     /locus_tag="KR294_001125"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HBH0239213.1"
                     /translation="MAYKGIGASPGVALGKALVVEHSELVIEKKSIDNVEAEIAKLED
                     AVAVSKEELVKVKEKASEELGAEEAEIFEAHLLVLEDPELIGSAIDKIKTESVNAEYA
                     LNEIKEMFVSMFESMDNEYMKERAADIKDVTNRILRHILGIKVVDLSALSEEVVLIAH
                     DLTPSDTATMNKKMVLGFLTDIGGRTSHTAIMSRTLEIAAIVGLNDITSKVKDGDFVV
                     FNGDTGEVIVNPDEETINKYTELKAKYEDERKALQLLKGKPSVTLDGKHVELAGNIGT
                     PNDIEGLIKNDAEGVGLYRTEFLYMDRDSFPTEEIQYEAYKAVLEGMDGKPIVIRTLD
                     IGGDKELSYLSMEPEMNPFLGYRAIRLCLDRKDIFKTQLRALYRASVHGRLRIMFPMI
                     SSLEELLQAKEVVKEVLAELDSEGVGYAKDVEIGMMIEVPSAAVISDVLAKHVDFFSI
                     GTNDLIQYTCAVDRMNQKISYLYNQFNPAVLRLIKTVIDNAHKEGKWAGMCGESAGDQ
                     KMIPILLGMGLDEFSMSPISILPARKLITSVKESDMKKLADDVLNMGTAEEIKSYIEK
                     TFNI"
     gene            27250..28800
                     /locus_tag="KR294_001126"
     CDS             27250..28800
                     /locus_tag="KR294_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBH0239214.1"
                     /translation="MRYKKRNIDKSSELSFQSLAKYFITFYIVIILIILSMFCINTIW
                     VMKKDNQDLLSTTSNRIEDRVGETIKLLNSLSKDNYIIDNSVNGIDKSKELSMYSDEF
                     GYMMICFVDKNIIVWDEEGGNISLAGRDYMQKLFATKKYQVTDSFAAGADGKTLNYTI
                     ASPIIKNGNVDGCVFAAIYFDEIKDILKQGKGQQQQNFILFGSENQIMNLTSDETAYG
                     EKYMKLSQKTKYLGTNAKKVEKDMFNNKSGDYWAFENGKLYFMSYKPIKNTNWSLFCK
                     VNFLDIFALNLIPMGAILSVITLVFIILICMEKSFMKKRMEVIDMLLGSVQELEKRIY
                     QTERPSEVDFKEIIQLTSKGLTDGLTGVVTRTVFFDQIYNRVEMEENDKLSVISFVDL
                     DDLKCINDLYGHEIGDMVLKNVGYVLREYEIKYNGLIGRYGGDEFVMLLSGFTSREEV
                     EDLLDEIAIRLHTEVLTDDGIIQTHCSVGAVVCSVKDNKDIDNLLKQADEALYYVKRN
                     GKGNYHLV"
     gene            28826..31528
                     /locus_tag="KR294_001127"
     CDS             28826..31528
                     /locus_tag="KR294_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBH0239215.1"
                     /translation="MKNVSKKFFVCTIIVLITFLCFSKFAIYVFDKQEKKETKVVENM
                     LNAYKNNIILNLTEKFNYSKDLTSVLVSNNYSIDKLKPIADEILKNNSCIYISVVEKY
                     NVAAFFSNSVKKDIINTPIQELNYSYSLANSIKGLVVEGPSKDQFSNGDVFLITNPIY
                     KNGEYWGEITVALDAKKVVDSFNLNKLKESGFEYELWRVHLDNGSKSTIEISTKDFNF
                     SKSHEIKFKLPTVWTLSIVYKNGWNNKNIDFIVFVILLIISILIGVMTFIYIEKKSIS
                     KELNQQSLKNLETGILNREGFLIKLQEHLNRKNNEIVLLYICITNYSKFAPVMSFEKR
                     QDYLTHIVKNLDNYIKSSHFIARISEEGFVLALEENCDKNELLNIEKGISLELLRKIK
                     VENKQVFLTIGYGSSRCVDDRKDAESLLLSAIEDYERRFPAMSPIHDFTKKCEDMLDE
                     KKQIVFGEYPDLEINKLSKVIYKYYKKVQRIMYKDYNIDIGNRRGYMRDVEVLIDYNS
                     ERMLYLFLIDICKFGKFNELFSIEIGDVILKEVSNKLKTIFSNYLYRINGDVFLGISI
                     DKESYLDTLHKVNEVFNSSLSVEDVLFDIKCNIGICQYPYHGENPYDLLEKVQIALEY
                     AKKDVKSNVKVYDKELTEEIYHENNIIKDLKKGLEEQTLEVWYQPIFNVSKNCYIKAE
                     ALIRLRNKEGGYYSAYEVITYAEKHGLIKDVGLYVLKKACDVTTKIKDKNIDFEQMQL
                     NLSVQQIVHKQCANDILSCIENCGLDKKYICVEVTETVLMETFEIVNVTLDKLKKEGI
                     SIALDEFGSGFSSINYLANLPIENLKIDKELVEQITYSKKQFELLKTIVQIAKINGMD
                     IVAEGVETKETLDLVVTSGVNLIQGHYFSEPLSEDKFIELMIEE"
     gene            complement(32034..32699)
                     /locus_tag="KR294_001128"
     CDS             complement(32034..32699)
                     /locus_tag="KR294_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239216.1"
                     /translation="MKGNIVQYNFADIEEEVYSLDYAIAWNTDEENVNIIPFTNKFCK
                     ESIESFCLGKINNFVEILNEGFVENHHYVHLDKMISVPKKKVNLVYQQDTHGYLLRDD
                     NDNLIPAKITSEQSKSISSKMELFSAGEEKCLINILLKADPSYILDVDSIKDKNILNL
                     GYESIDRYKEYNFDDDKILIFFINKKRYSVIMKKTNNSDNDLVSRNNAIKELFTNKAG
                     NLN"
     gene            33043..34473
                     /locus_tag="KR294_001129"
     CDS             33043..34473
                     /locus_tag="KR294_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4116 domain-containing protein"
                     /protein_id="HBH0239217.1"
                     /translation="MDIKNKIKSIFLPEKNDYLDDEEFEYDIENNEEDLKEDNKVHLN
                     DLSRVKYDYRELKDIENQTEEICLLAVKQDGTIIEFVKDKTYKVCMEAVKQTYKSLKY
                     ITNQNEDICIEAVKQNYRALYYINNKTENVLIEAIKNASTYDVMEVFKFVEEQTEDVC
                     LAFIERASKNDVAEILKGIKEQTPAICLEAVKKDGKSLAYVKEQSNSICLEAVKENYS
                     ALSCVKEQTEEICIEAVKQNDFALYYVNEQTEKICMEAVKRSYMALQYVNKQTEEICL
                     EAVRIDGRALQYVKEQTEEICLESVRQNGKVLQYVKKQTENICIEAVRGSFEELEIKE
                     ILSYVKIPTERIFVEAVKQNGKILKYVENQTELICLEAVRENYNALAYVKEQTEKICL
                     EAVNQSYEALKYVKEQTEEVCLKAVKQDYRMLKYVNNQTEKICLEAVKQNYRALEFVD
                     NQTEKVCLEAVKQNRKALQYVKQKQS"
     gene            34841..35419
                     /locus_tag="KR294_001130"
     CDS             34841..35419
                     /locus_tag="KR294_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HBH0239218.1"
                     /translation="MFKRYAEKMTSVLICNNMIDNNESKVYSYGFEILIAFIVNITTM
                     LFIGFLFGKFTYVLFFLMCYCPIRQFSGGYHADNYFRCLLTFIFIILSTILIIENINI
                     DLFKNIIMIIASVSWVGICVLCPIEHRSNPISDREKLVYKKTAIFISTVVLLITILSL
                     SLSIFVDYFTYSAFAMFWIFVMLVLGKLKAKV"
     gene            35449..35595
                     /locus_tag="KR294_001131"
     CDS             35449..35595
                     /locus_tag="KR294_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic lactone autoinducer peptide"
                     /protein_id="HBH0239219.1"
                     /translation="MKKFIVRFMKFASSLALSTAILSANSTCPWIIHQPKVPKEISNL
                     KKTN"
     gene            35900..37279
                     /gene="scfB"
                     /locus_tag="KR294_001132"
     CDS             35900..37279
                     /gene="scfB"
                     /locus_tag="KR294_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioether cross-link-forming SCIFF peptide
                     maturase"
                     /protein_id="HBH0239220.1"
                     /translation="MSMIHKFSMNGYNIVLDVNGGAVHVLDDVAYDLLDFYKEKSKEE
                     ILEILKSKYQEEKINEAYEEILNLEKEGLLYTEDTYQYHPSFVHREPVVKALCLNVAH
                     DCNLKCKYCFAAQGDFGGEKELMSFEVGKAAIDYLIANSGSRKNLEIDFFGGEPLMNF
                     EVVKQLVDYGRSVEKDYNKNIRFTITTNGVLLNDEIIDYINENMHNVVLSLDGRKEVN
                     DNMRPTLNDKGSYDITLPRFKKLVEKRAKDKYYYIRGTFTRDNLDFSKDVMHFADLGF
                     KLTSVEPVVGDESNPYALREEDLPKIFEEYEKFAVEYADRQLQGDGFKFFHFMIDLNQ
                     GPCVIKRITGCGAGNEYLSVTPNGDIYPCHQFVGNEEFKMANIFDEEIVLPENLKNMF
                     REAHVYTKEECKQCWNKFYCSGGCHANAINFNNDISKPYELGCEMQRKRTECSIMIQA
                     KLMLEGATN"
     gene            37308..37805
                     /locus_tag="KR294_001133"
     CDS             37308..37805
                     /locus_tag="KR294_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HBH0239221.1"
                     /translation="MIRDYLEDKPLIDESVFVAKSADVIGNVKIGKDSSIWYNAVVRG
                     DEGPITIGENTNIQDCSIVHGDTETIIGNNVTVGHRSIVHGCKISDNVLIGMGSIILD
                     NAEIGEYTLIGAGTLITSNKKFPPGVLIMGSPGKVVRELTEEDKKYIDESYEWYLEAA
                     QNQKY"
     gene            38103..39767
                     /locus_tag="KR294_001134"
     CDS             38103..39767
                     /locus_tag="KR294_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/ABC1/UbiB kinase family protein"
                     /protein_id="HBH0239222.1"
                     /translation="MRISYRNLKRYREIGYVLIKYGFSFIVERLNIEGIAYKIPLFDP
                     PEEIKNMTTGERMKRVLEELGPTYIKIGQILSTRKDLLDQDIIDEISKLRDDVEKFDS
                     NIAIDIFKEEVGLSIEEIFLEFKEEPIAAASIGQVYEGVLKTGEEVIVKIQRPNIEKI
                     IKSDLEILRTIANTLKDLKKDFNLDLVQMIEEFQTQLMRELDYTFEAINATKFSRIFK
                     NSDEVYIPKVYSEYNTKKILVMEKVNGTKLSDVEKIRRLGYNTKTIVEIGVRSFFTQV
                     LSHGFFHADPHPGNIFVIAKNKIAYIDFGMIGIIDNKTLNQLNEIALAGVEKNVDKII
                     YLLIEMDALNGEADIKGLRQDLLYLIHYYYDISIEKINVTDILNELFRFFRQYKIVMP
                     AQFVTLAKTVITLEGTSRTLNTDFSFGSMGKEFMKHHYKSKFNPKNVVLSSRQNVEEI
                     LLDIKTIPKQLKAILKNIERNNIKMQIEDVKMTRLENCIIELTSQISLSLVLASIIVG
                     SSLIIASPNIENNIWIKFTAIAGFFISFIIGLCLVIRSIRSKYKKD"
     gene            39780..42230
                     /gene="recJ"
                     /locus_tag="KR294_001135"
     CDS             39780..42230
                     /gene="recJ"
                     /locus_tag="KR294_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HBH0239223.1"
                     /translation="MKKWILKYKGKIEESEFSKKLNISPEICQILKNRGICTEKDSEI
                     FMNPSLDYLRDPFLMKDMQKAVDRIKLAVEKNEKIWIYGDYDVDGVSSTSILCLYFKS
                     IGYNVDYYIPNRLEEGYGINEDAIKLISSRGCDLIISVDCGITSVSEVNTANDLGIDV
                     IITDHHECQSEIPSAFAVINPKQEDCNYPFDSLCGCGVAFKMIQALTPKEEFKTSMYN
                     YLEIVTLATICDIVPLIDENRIIVKNGLKSMKEGKNIGLRELIKVCGVESDKIGSSHI
                     GFAIGPRINASGRLGYSYLGVELFTTQSQEEAVEIASILEEKNNERQMIEAKMYHEAE
                     EMLKSNSRYNDDKVLVLAKEGWQHGIIGIVASKLTEKYYKPTILLGIENGEATGSARS
                     IKGFNIFEALIKCKDLMTKFGGHEQAAGLSLDSDNVEILANEINKFADYNLTEDDMIE
                     NVNVEFELQENVINLNLVEELHKLEPFGLNNPNPRFIVRNYILKDLKVIGKNQQHLKL
                     SIEKEKSYECIGFNMSHLKSMYKVGDKVDVLFQLDENNYMGNRKVQFLLKDIRLARPK
                     SASNDKLSLKLMSKIIPKDTQSLYNISVSDFELFDGNTDINIFDYFEKDTLIISNSIN
                     GFYRAMSDISLIDLDFNINYNIIEDVSKNTDKLELIFSPNIDKIDLKRYNNIILYDYL
                     YNKGEYSYIYENKREESEIIKYYNKTDLLYLKNVVSNIVPSRDEFITIYKQALIKKEI
                     DLDMVNIRETFNVIPLKFFTILNVFRELNLLDFNLNYEKNSVLIRILPKPQKKLDLNE
                     SLILNNLKNLEKQYNSSY"
     gene            42243..42755
                     /locus_tag="KR294_001136"
     CDS             42243..42755
                     /locus_tag="KR294_001136"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HBH0239224.1"
                     /translation="MDLKNFIRNIDDFPKPGIDFKDVTTLFKDGDAFKYAVDSIVEEL
                     KDKDVDLVIGPEARGFLMGTPVAYALGVGFVPIRKPGKLPGEVESYEYGLEYGTDTLE
                     IHKDAIKKGQKVAIVDDLLATGGTMEAAAKLVEKLGGEVVSMQFLIELKFLNGREKLS
                     NYDVNSLIKY"
     gene            42829..45036
                     /locus_tag="KR294_001137"
     CDS             42829..45036
                     /locus_tag="KR294_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003229747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HBH0239225.1"
                     /translation="MHDKELQEIIEKIKVYAPNANFEMVEKAYNLAKKAHEGQYRKSG
                     EPYFIHPLAVANILIEMELDIETITAGLLHDVVEDTEYTYEDIKKEFGKEVADLVDGV
                     TKLGQIKYRSKEETQSENLRKMFLAMAKDIRVILIKLADRLHNMRTLKYMPPEKAKYK
                     AKETLEIYGGIAHRLGISKIKWELEDRALRFMDPEGYYDLVSRVSMKRSQREDYIQGI
                     VELLKDKFKDLSIPCDVYGRPKHFYSIYRKMQKKHKTFEEIFDLTAVRILVDNVKDCY
                     AVLGIVHTLWRPIPGRFKDYIAMPKPNMYQSLHTTVVGPDGEPLEIQIRTHEMHNIAE
                     NGIAAHWKYKEGISSKESKVEEKLQWLRQMMEWEKDLKDPQEFMDALKEDVFNSQVYV
                     FTPKGDVIELPAESTPIDFAYRVHTNVGNKCVGAKIDGRIVPIDYKLQNGNIVEVLTS
                     SNSNGPSRDWLNIVKTPNAKSRIRQFFKKERREENVDRGNTILEREFKKHDIPQKDPL
                     VEKYMALVAKKFNQPSVEDLIATVGYGGIMSSQVVSKVKDLYLKEVKKAKKEQQIQEE
                     DLNKHNISETEYSKKRKKNASQGIIVKGLDNILVRFAKCCNPLPGDEIVGYITKGRGV
                     AIHRADCPNANNNGDFFQNRLVEVSWSSAGKGKFEAEIQIKAIDRRGIVNEITHIVAM
                     DKLSLNGINARKGKDSIVSINLLVEVNDTEELKILMKKLKAIPGVESIYRMTN"
     gene            45061..45510
                     /locus_tag="KR294_001138"
     CDS             45061..45510
                     /locus_tag="KR294_001138"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003517065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HBH0239226.1"
                     /translation="MRAVVQRVSSSKVTVDENTIGQINKGLLVLLGVTHDDKSSDVDY
                     MIDKILNLRIFEDENDKMNLSLMDIGGELLVVSQFTLYGDCRKGRRPGFSNAARPELA
                     NNLYEEFVKKAKDKGVTVGTGQFAAHMMVELTNDGPVTILLDSSKSF"
     gene            45525..46139
                     /locus_tag="KR294_001139"
     CDS             45525..46139
                     /locus_tag="KR294_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBH0239227.1"
                     /translation="MIIKKFVDSYFGVNTYVLGDEKTKKCAVIDPGGSLVETLSFVKE
                     NELNIEYIILTHGHGDHIGYVKDIKEKTGAKVVAHVDEKELLNDKNKNLSYTMRCGAQ
                     EFDADIYVNDKDKLELGELKMTFLHTPGHTQGCMCIRVEDEMFTGDTLFAGSIGRTDL
                     YSGDFNQMEKSLKKLCKYEDAVRVYPGHGPTSTLGVEKKTNPYM"
     gene            46230..47786
                     /locus_tag="KR294_001140"
     CDS             46230..47786
                     /locus_tag="KR294_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coproporphyrinogen III oxidase"
                     /protein_id="HBH0239228.1"
                     /translation="MLYVFLKGHDYKYEVAELIKLFTSEFKFKDSNANNNIESKHLIN
                     RLIYENGVLFSSTEYYENGNLKYESIQNIENMNLEFLDGFDSSKTIEEFLNSLDSESK
                     RNFKKLCKENIKKSMFLVLKQVFNSYVPWGILTGIRPVKIVHNLMDKKLDDNSIRTIL
                     KDNYFIIDEKIDLALEIAKRERLFMYPIDKNKISLYVSIPFCPTRCVYCSFPSNSLKQ
                     FGHLKREYVYKLIEEIKGFAKVIKDTKKEVETLYIGGGTPTTLDEEELDLLINSLFNE
                     LDLSKIKEFTVEAGRPDTITEQKLRVLKKHNVSRISINPQTMNDDTLVKIGREHRVSD
                     LVDCFNMARRMGFDNINMDIILGLIDEDLNMVKNTLEEIKKLSPESLTVHTLAIKRAS
                     NLNINMDRYKEHLTQYEEMVKMIDLSMKYAKDMGLNPYYMYRQKHMLGNLENIGYAKE
                     GYECIYNIQIMEEKQSNYALGAGAISKFVYVDEDRIERVENVKNVEQYIERVDEMIKR
                     KKEEVYKNVD"
     gene            47776..49038
                     /locus_tag="KR294_001141"
     CDS             47776..49038
                     /locus_tag="KR294_001141"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HBH0239229.1"
                     /translation="MLTKAPRGTKDITPKEAYKWRYVENKFREICALYGYEEMVTPIF
                     EHTELFKRSVGDTTDIVQKEMYSFKDKGDREITLKPEGTAGVVRAFIENKLYADTQPT
                     KLFYVTPCFRYERPQAGRQRQFHQFGIEALGSDTPSMDAEIIALAVQFFNEVGLNDLV
                     VSINSVGCPVCRKEYNALLKEYLDSKADILCDTCNERREKNPMRVIDCKNPTCKENIK
                     DIPFIADHLCDDCKSHFDKLQEYLKEMNINFVIDKTIVRGLDYYRKTAFEIISNDIGA
                     QSTVCGGGRYDGLVEQLGGPKGISGIGFGLGIERLLLTLEGNGIEIENPQSTDIFIVT
                     IGEEANTRSFKLLKDLRQNHISADKDHIERSVKAQFKYSDKINSKFTIVIGDDELKND
                     TATLKNMKTSEQTTVKLSTLVEELKQKL"
     gene            49112..50899
                     /gene="aspS"
                     /locus_tag="KR294_001142"
     CDS             49112..50899
                     /gene="aspS"
                     /locus_tag="KR294_001142"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HBH0239230.1"
                     /translation="METLKGLKRTHYCGELREKNINEEVVLMGWVQKKRNLGGLVFVD
                     LRDTSGLCQIVFDTDVDKEAFEKAEKLGAEFVIAVKGKVCERQSKNPNMLTGDIEIFA
                     TELRLLNKSETPPIYIKDDDDVSEALRLKYRYLDLRKPSMQRNLKLRHKVMNITRNYL
                     SNNRFCEIETPFLIAPTPEGARDYLVPSRVNPGKFYALPQSPQLYKQLLMVSGMDRYF
                     QIVKCFRDEDLRADRQPEFTQIDCEMSFVEQEDVMSMIEGLLEAIFKEVLDVELALPL
                     PKMTYAEAMSKYGSDKPDTRFGYELTDISDVVCNCGFKVFADATQPGKSVRGINVKGK
                     ADDFTRKQISSLEEHAKTYRAKGLAWMKVGQEGVTSPIAKFFNEEEMNAILTRMNAEV
                     GDLLLFVADKNSIVFDALGQVRLEVANRLNLLDKNVYNLLWVTEFPVFEEDEETGTFS
                     AMHHPFTSPMDEDLDKLEEGDKSSLRAKAYDIVLNGYEIGGGSVRISNSDVQSRMFKA
                     LGFTEERANEKFGYLLEAFKYGTPPHAGLAFGLDRLVMLLAGTDNIREVIAFPKNQNA
                     VCPMTNAPTLAEDEQLEELSIKVDIKDNE"
BASE COUNT        20594 a         5151 c         9034 g        16432 t
ORIGIN      
        1 tcattaatat ttaatcagga agtccactat agatatatag aaaaaataga tatgcttgtt
       61 acaagaatgg attttggact tggtaatcca aatagtgtat tttatcatat ggttactata
      121 tatgcagcat atatattctt aagatataaa gattataata aatgggatag aataatttta
      181 tttggttctg cattttttgt ttatcaaacc acatatagta gaactggatt tttcactata
      241 ttagcaggat taatatttgt agaaataata agatggatag atataaaaaa aataaaagga
      301 ctaccaatgc ttctaaagac attaccgata atacttactt tatttagtgt aattattggt
      361 acagtatttg ataaaagcac tttattaaat agattattag caagtagacc taagttctgg
      421 catgtatact tggctgaaaa ggggaacttt ctaaaacctt ttggaaattc atatagtcct
      481 gctataaaag caactaatcc attagatagt tcttatgtat atataattag tgtactagga
      541 gtagttgctt gtatattatt tatgtatttg atgtataaag gaatagaaag ctttatagaa
      601 aaagataaaa aagcatattt agtagcttta tttatatttt tactatactc ttttgcagaa
      661 aatttattat tagaagcttc atttagtttt gcagtagtat tactaataaa agaagtgata
      721 ttaaatgata aaagggaaat agatttgtgg aagatgaaaa gtaggaggta gtaatgttaa
      781 tatcattaat aatgccaaca ttaaatagat atgatgatat atacttactt atggacagct
      841 tagaaaatca aacttacaaa aactttgaac ttatagtagt agaccaaaat gataatagca
      901 aagttaaaga aatagttgat aaatacattg ataagttaga tataaagtat ataaaaagct
      961 ctaaaaaagg attgagttat aacagaaatg taggcataga caatgctgta gggcaaatta
     1021 taggtttccc tgatgatgat tgtgtctacg aaaatgatac attagaaaaa gttataaatt
     1081 tctttaataa aaataaagat tataaaatat acagttgcaa aactatggat tcaaataaag
     1141 ttgatgcatt taagaaaatg tatgatggaa cttgtgatat cacaagttcc aacgttttgg
     1201 atactataac atccataact ttttttattg attttgaagg taaagactat acaagatttg
     1261 atgaaaaatt gggtgttggt ggagagtttg gtgctggtga agagatagat tatgttttaa
     1321 acttattgag tttaggtttt aaaggaaaat actttggaaa tgatataatt taccatcctg
     1381 caaaaaaaca ttctaaatct aaagaaaagt atcaaaaaga ttataactat ggaagaggct
     1441 ttggagcgct ttgcaaaaag gaaatagtct atagaaaaaa ttataagttt gcaaaagtta
     1501 tggtatcaaa acttgtaaga aatataggag gtcttatatt gagttccaat agagattatc
     1561 atagtgccac tataaaggga agaattaatg gatttagaca gtacaagtta taatgaggat
     1621 ggtgtttatg gacaaggtta aatttttaat aaatatgctt ttggcttttt ttatatatcc
     1681 atttaataag cataagttta atggtagaaa tatctggctt ataggtggac attcagggga
     1741 tatatacaat gataattcaa agttttttta tgagtatatg ctaaaagaac ataatgatgt
     1801 agaaacttat tgggtagtaa ataaagacag taaagtattt gataaaattc caggcaaaaa
     1861 attaataaga ggaagtgtag aaaactatct gtattattac aattcaaaag ctatagtatt
     1921 ttcacatgca ccatcagcag atatagcacc atacaatttt gctgtacctg ttcttaatta
     1981 ttttcataaa aaaacgataa aagtgttttt aaatcatggg actataagtt ttaaaaagag
     2041 aaaacctatg aacaaaaagt tcaaaaacat tatagataac ctatataaaa gctataatat
     2101 agttacagca agttctgaat ttgaaagaaa tgttatggta aatgattggg gaatgttaga
     2161 tgactcagtt tatataattg gaaatgcaag atatgacaat ttaccaacaa atgaagttgc
     2221 acaaactcga gatatattat atactcctac atggagagat tggataaaat ttagttcagg
     2281 aaaatttacg gatacagatt attttaaaaa tataatgaat tttttaaatg atgataaatt
     2341 aaataaaata ttagatgaga aagatataaa tgtaaaaatt tatatgcatc atcttatgca
     2401 tgagtttata gatgatataa aagaaaatat aacaggaaaa cgaattgtgt ttttagataa
     2461 aggggtaact ctagcaaatg aaatcagaaa atcagctgca aatataactg attattcaag
     2521 tgtagccata gactttttgt atatgaatag acctatcttg ttttaccaat tcgatttgga
     2581 tgaatatatg gaaaaagttg attcatatat agatttaaaa agtgaaatgt ttgggtcttt
     2641 ggcttataat aatgatgaag ccgtgaataa acttattgat attattgaaa ataattttga
     2701 ggttatggat aaccaaaaaa atgaaagaaa taagtttttc agatataatg ataataagaa
     2761 ctgcaagagg atatatgatt gtgtattaag taaaattaaa taaatatttt ataaatgatg
     2821 aggaaggtaa tatgaagaag aatttagtat ctataattac tcccatgtat aattctgaaa
     2881 aatttattga agcaaccata aaatcagtat taaaccaaac ttatcaagaa tgggaaatgt
     2941 taattattga tgattgctca acagataata gtcctaatat agtcaaatct tatatgcaac
     3001 aggatagtag aataaaatgt ataaagactg agactaataa gggtgtctct aatgctagaa
     3061 atttagcact aagtaaggca acaggacaat ttatagcttt tttagatagt gatgaccaat
     3121 ggaatagtag taagttagaa aaacaagtaa attttatgtt agaaaatgac tatgtaattt
     3181 catttacttc atatgaactg atggatgaaa atgataaaaa attaaacaaa gtaataaaag
     3241 ttccacctaa tgtagattat agaagattat taaaaggaaa tatcttagga tgtcttactg
     3301 ttgtgattga taagtctaaa ttggattttg aaataagaat gagtggtgta agacatgaag
     3361 attatgtttt atggttatcg atattgaaaa aagggcatat tgctcatgga ataaatgaag
     3421 ttctagcatt atatagaaaa tctagcaatt ccctaagtgg taataaaata aaagctgcta
     3481 tgtggacttg gaatatatat agaaatatag aaaaaatacc tttatacaaa gctatatact
     3541 actttattaa ttatggaata aacggaatca aaaaaagtta gacagagagg aagatttaat
     3601 taatgtataa atataaattt actgtattta ctccgacgta taacagagct catttacttg
     3661 aaaatttgta caatgattta aaagctcaaa cttatgattt caatgatttt gaatggttga
     3721 ttgttgatga tggaagtagc gacagtacta aagagttagt tgaaaaattt atatcagaaa
     3781 ataaattaaa tataagatat atatacaaag aaaatggagg aaaacatact gcaataaatc
     3841 taggtgtaaa aaatgcagat ggagagctat ttttcattgt agatagtgat gatggtttaa
     3901 ttaaagattc tcttgaaatt gctaatgatg agtgggattc tttagagaat aaagaaggat
     3961 ttagtggagt tgttggactt tgtgtatatc caagtggaga tttgataggg acagaaatgc
     4021 ctgaagataa gaaaatatgt cactttgcag acctatattt taagtatggc gttaagggag
     4081 ataaaagcat agtatttgta actgatgagc ttataaaatt tccttttcca gaaagaaaag
     4141 aagtgagatt tttaccagaa agtgtagtat ggaatgaaat gtctaaatac tataaagtta
     4201 tatgtgtaaa taaacctatg ataataagag attatttgga tgatggtttg actaagaata
     4261 tattaagtaa aaatgcatta agaggtagag cattagagtt tttatattta ataaatcaaa
     4321 atacatatcc attaagtaga tatccatata tgtggataaa aaattacata aatttagcca
     4381 gatactcatt gttgtctgat agtcattatt ttggtgaatt aagaaaagta tctgataaat
     4441 tgttgtattt agcattattc ccattaggat attacaaata tattggacaa agaaaattag
     4501 tatctaagta aacttgttgg tatagtactg ctagttgcta tataaggaga gtaaaaatat
     4561 gaatgagcct ttagtatcga taattactcc tgtttataat tcagaagagt ttttatcaga
     4621 gacgataaag tcaatccaaa atcaaactta taaaaattgg cagcttttat tagtggatga
     4681 ttgttctaag gacaattcaa gtgaaattat aaaaagtttt cgaaaagaag atgctagaat
     4741 aaaatatata aagcttgaaa aaaattctgg agctgcagta tctagaaatg ttggtattaa
     4801 gaatgcggaa ggtcgattta ttgcatttgt agatagtgat gatttatggg atagtagaaa
     4861 attagagatt cagatagaat atatgttaaa agaaaatgta ggtttttctt ttacatctta
     4921 tagatatatg agacaagatg ggtcaaaaac gaataaggtt gcaagagctc ctaagaaaat
     4981 tgactatgaa ggattactta gaaatactat aataggatgt tctacagtgg tcattgataa
     5041 ggagattgta ggagagttca gcatgccttt ggtaagaaga ggacaagata ctgcaacctg
     5101 gttacagtta cttaaaaagg aaaaatatgc atatgggatt caagaagatt tagtgaatta
     5161 cagattagtt ggaaattcta tatcaagtaa caagataaaa gcattaaaac gaacttggaa
     5221 tacttataga aatgttgaaa atttaagttt accaaaaagt ctatatgtat tttgtttcta
     5281 tgtttttaat gccattaaaa aaagagtata agttttatat acttggaggt aaaaaaatga
     5341 aaatagctat agctgggacg ggatatgtag gtttggttac aggtgtttgt ctagcagagg
     5401 taggcaatga aaatgtagtc tgtgttgatg tagatgaaca aaaagttaaa tcaatgaaac
     5461 ttggaatagc acctatatat gaagaaggcc tagaagaact tatggttaaa aattacaaca
     5521 gaggaagaat agattacact acagactata aaaaagctta tgaagatgta gatgtaatat
     5581 taatagctgt aggtacacct gagagaagtg atggctcagc caacctagat tatataaagg
     5641 cagttgcaaa gcaaatagct gaaactgtga caaaagatac tctagtagta ataaaatcta
     5701 cagttccaat tggtacaaat gaagagatag aagattatat aaatagaaac ctaaaaaatg
     5761 atgtaaaagt agagcttgca tctaatccag agtttttatc acaaggaaca gcagtaaaag
     5821 atactctaca tgcttcaaga atcgttatag gtgtagaaag tgaatgggct agagaaatat
     5881 tagaggaaat ctataagcct tttaatcaac ctataatagt tacaaataga aatagtgctg
     5941 agatgataaa atatgcatca aataacttct tagctcttaa aatatcattt atgaatgata
     6001 ttgcaaatct ttgtgaaata gcaggagcta acatagaaga tgtagcttta ggaatgagtt
     6061 atgatgatag aataggaagt aagtttttaa aggcgggaat aggatatggt ggttcttgct
     6121 ttccaaaaga cacaaaagct cttcactggt tatctgaaca taatggttat gaattaaaaa
     6181 cagtaaaagc tgcaatagaa gttaatgaaa gtcaaaaact taaattagtt agaaaggcat
     6241 ctaagttagt agagagcttt caagatatga aggttgctgt tttaggtttg acttttaagc
     6301 cagatactga tgatataaga gaagcaccat ctataccaaa tataaaatat ttgctcgaaa
     6361 gaggggcaag agttactgta tacgacccaa ttggtgtaaa taatactaag aaaatatttg
     6421 gtgactctat actttatgct gattctgtag atgatgcgat agaagatgca gagatatgtt
     6481 ttataatgac agaatggaaa gatgtattaa attatgatat acataagtat aaggaaaaga
     6541 tgaaaaatcc tttagtcctt gatggaagaa attgttataa aattaaagat atggaagagt
     6601 taggaattga gtattattcg ataggaaggt aaatattatg aagactgttt gttatttagc
     6661 tgatgggtca aatcctcata ctttaaaatg gtgtagtttt tttaaaaata aaggatatga
     6721 cattcatgta atctctttaa atggaggtca catggaagga ataaaaattt ataattttgg
     6781 ttctaatgta gaagaactaa aaaatgaaaa tatttctaaa aaaacgggat acttaggttc
     6841 aataaagcag ataaagaagc tagtaaatga aataaagcca gatatattgc atgcacagta
     6901 tgcaagtagt tatggattta taggaagtct acttgggtat catccatata ttatttctgt
     6961 ttggggtact gatatttatg atttccctaa taatggtttt atacaaaaac aaattataaa
     7021 gcataacttt agaaaagcag actatatctt ttcaaatagt agagatatgg ctaaagaggc
     7081 taataaatat acagctaaac atgtagatgt aacctttttt ggagtagata tggataggtt
     7141 taagcctatg gaagtagaaa aagaagacgc ttttgtaata ggaattataa agagtttaga
     7201 aaaaaaatat ggaatagaat atttaataca agcatttaag atgcttaaag atgaatataa
     7261 agataagaaa ataattctta aaataggtgg ctctggaagt cagatggaca acctaataaa
     7321 tttagctaaa gaattgggta tagaaaatga tgttcagttt ttaggaagaa tatctccaga
     7381 aaatgtaagc aagactttta attcttttga tgtaactgta tttccttctt taagagaggg
     7441 atttggagtg gcagctatag aatcagaagc atgtgaagta cctgttatag ttacaaatgt
     7501 aggaggacat ccagaatctg tatgggaaaa tgaaactggc ttaattgtag aaccaaaaca
     7561 accagaagaa ataaaaaatg ctataataaa actaatggaa aatgatgaac ttagacttaa
     7621 tatgggtaag aaagggcgtc aatttgttag agaaaattat gaggttaatt taaactttaa
     7681 tgatatagaa aaaatttatg attctatatt tgataaatat aaaaaataaa atgaaaaaat
     7741 acagcaaaag atagatgttg ttggctatgc ttaggtgcgt agcttttgct gtttaaagga
     7801 gggcttctag ttatgcgaga aagtatagat ttagagaaag aaagcttttt taataggctt
     7861 tttaaaaaat ataaatttag acatttaaca ctattaattc tagatatttg tagcgtacta
     7921 gtagcgtttc gaatgtcttt aagcttgaca ggtaatttaa atgcatttac cactaatgat
     7981 ataataattt cagcgtgtat atatatagta cttcatatag tatcatttag attgtttaag
     8041 tgctacaaca cattatggag atatgcagga gaagaagaaa ttatatctat ttttatggca
     8101 actttagctt atttaattcc gatttatata ataaataaat tattagggtt tgattatcct
     8161 ataatgtttt atgtattaaa tacaatattt attataatgt ttacaagtgg cgcaagaata
     8221 gcctatagag ctataagaat agtcatgaac aagacatatt ctagaggaaa ggtttcaaat
     8281 atccttataa ttggtgcagg agatgcagga gaaatggtta tacaggaact aaaaagaaat
     8341 ccagaactta aaaaagtagc agtggctata attgatgatg ataaaaataa aattggaaga
     8401 ataatccata atgtgaaaat tgtaggaaca acttcagata taaaagatgt ggtagaaaag
     8461 tacaatgtag atgagataat cttttcaata gcaaacatag agaaacgtag aaaaaaagat
     8521 attattgata tatgtaaaaa cactaactgt aaaataaaga caataccagg aatttacgaa
     8581 attatagatg gaaaagttga tataaaacag attagagaag tagagataga agacttgttg
     8641 ggtagagagc ctataaaaac aaatttaaga gagataagta attacattga gggaaaagta
     8701 atcttaataa ctggaggagg aggctcaatt ggttcagagc tttgcagaca gattgcagga
     8761 tttaatccta aagagcttat tatagttgat aattatgaaa ataatgctta ctcaatacaa
     8821 caagaattac ttagaaaata taaaaataaa ttagatttaa agacagtaat agcatcaata
     8881 agagaagaga aaagaatgga tgaaatattt aataaatata aaccagaagt ggtatttcat
     8941 gcagcagcac ataaacatgt tcctcttatg gaatcgagcc ctggcgaagc tataaagaat
     9001 aatatatttg gaactttaaa catagctggc ttgtcttcaa aatatagagc taagaaattt
     9061 gtccttatat ctacagataa ggctgtaaac cctactaaca taatgggagc tactaaaaga
     9121 gctgctgaaa tgattataca gactatgaat gctgaaagcc agactgaatt tgttgctgtt
     9181 agatttggaa atgtgcttgg tagtaatggt agtgtaattc cactttttaa gaagcaaatt
     9241 gaagatggcg gaccagtgac agttactcat ccagatatta ttagatattt tatgacaata
     9301 ccagaagcag taggcttagt catacaagct ggtgctatgg ctaaaggtgg agaaatattt
     9361 gtacttgata tgggagaacc tgtaagaata ttggatttag caaaaaactt aattaaattc
     9421 agtggatttg agccagatgt tgatataaaa attgaatttt ctggtcttag accaggagaa
     9481 aagttatatg aagaactact tatgtcagaa gaaggtctgt tggatacaga gcataaaaag
     9541 atttttattg gtagaccaat agatgttgat agagaaaaaa taacaaaata cttaaaactt
     9601 ttaagagaaa ttactaacaa tgaagaggtt gaaaaaatag atggtattat gagggaatta
     9661 gtgccaactt atattaaacc agaagatgct aatatcaaag aaattgcaac aactagagaa
     9721 aagtagaata tatttctaat ttgtaaccag ggggagcaaa aagaaacaaa tatatactaa
     9781 aaagaaacaa aagattacaa aaagattaca aaaagattac aaaaaaggtt gcaatttatt
     9841 ttgatgtaag atagaatgtt aattaggaat tggaaacgaa ggaacaaaat gttaaatttt
     9901 cgaaaggatt aggtatttga gattatgatg aatattaaaa ataaaaaaca tatattgaaa
     9961 aaatttatag ctatggtgtt aatagcagga gttgtcacag tagaagcagg agcaataacg
    10021 gctagtgcag cagagccaac taattcacct atgagtgcaa cagtagacca gtgtgatttt
    10081 ttaaatgtaa gaagtggagc tagtgcaaat gatgcagtag taggaaagat aaacacagga
    10141 gacaaagttg aagttttaga attacattca aatggatgga ttaaaataaa aagtgttgac
    10201 aatgttacag gatgggtaaa tggagattat ttaactattc aaggtggaaa tgtagatgca
    10261 aaggtacaaa atgttttaaa cttagcattt aagcaacaag gtaagccata taaatgggga
    10321 gcaactggac caaattcttt tgattgttct gggttcactt cttatgtcta taaaaatgga
    10381 gcaggagtta atttaccaag agtatcaaga tcacaagcaa cagtaggaaa gaaagtatca
    10441 agagcagaat taaaaccagg agatttagtt ttctttggtt caggtggttc aataaatcac
    10501 gttggattgt atgtaggaga ttctaaattc atacattcac cacaaacagg agatgtagta
    10561 aaagttacta gcatggctcc aggaactaat tatgcaagaa gacttataac tgctacacgt
    10621 gttttacaat aataatagat attgatttac ataggattga atattaacat taaatatata
    10681 attacattta atgttttaca tagagattta agagtttagt aatattaaaa tagtgatgaa
    10741 cgttataaaa acagcaaaga agataaattt ctttgctgtt ttttttataa taaattattt
    10801 catattataa tcaaatatca aatataaatt ttaactatat tattcaatat ttgacagata
    10861 atatgaattt tagatatact taataagaag tatattgtag aaaaaataaa tttaaaaaat
    10921 taagggggat gaaatgaaaa aaataagtat attagtatta tcattgataa tgacacttac
    10981 tatgtgtagt gtaagttcat ttgctgattc atcaaatgat aaggaaatga gagctgcttg
    11041 gatatctaca gtttataatt tagactggcc taagactaag aataatgaag ccaagcaaaa
    11101 aaaggaatac acagatttat tggacaaatt aaaaagtgta ggaataaata cagcagtggt
    11161 tcaagtaaga ccaaaatcag atgctttata taaatcaaat ataaacccat ggtctgaata
    11221 tcttaccggt acacaaggta aagaccctgg atatgaccca ttaccatttt taatagaaga
    11281 agcacataaa agaggaatgg aatttcatgc atggtttaat ccatatagaa taactatggc
    11341 agatgagagc atagataaat tgccagcaaa tcatccagca aagaaaaatc caagctgggt
    11401 agttaaacat ggaaataagt attactacga cccaggttta ccagaagtta gaaagtacat
    11461 agtggatagt atagcagaag tagttcaaaa ttacgatata gatggagttc attttgatga
    11521 ttacttctat ccaggagtaa gtttcaatga tactgcaaca taccaaaaat atggaaaagg
    11581 acaaaataag gatgattgga gaagagaaaa tgtaaatact ctacttagag atgtaaaagc
    11641 gtctataaag agtataaagc ctaatgttgt atttggtgta agcccagcag gtatatggag
    11701 aaataagagt agtgacccaa caggttcaga tacatcaggt aatgaaagtt atgtaggtac
    11761 atatgcagat acaagagcat ggataaaaca aggattgatt gactatgtag ttccacaact
    11821 ttactggcca attggtctta aagcagcaga ttattctaaa ttagtggcat ggtgggctaa
    11881 tgaagtaaaa ggaacaaatg tagacttata cataggacaa ggtatatata agcaaggtca
    11941 atcgagttat ggtggacaaa atatagcaaa agaaatagta caacaagtaa cattaaatag
    12001 aaagtatagt gaaataaaag gtagtatgta tttctcagct aaagatatag caaatagtac
    12061 ttctatacaa aaggatttaa agagtttata ttctagtagt gaagaaccag ttactccacc
    12121 atctaatgtt aaagtggaga aattaagagg cgacgaaaga tatgacacag cagtagcaat
    12181 aagtaaaaaa ggttgggcta caaattcaga tacagtagta ttagtaaatg ggtactctat
    12241 agttgatggt ataacatcaa caccacttgc tacatcaaat gatgctccta tactattggt
    12301 aaataaggat aatataccta catccactaa gaatgagtta aaaagactta atccaagtaa
    12361 agttatttta attggaggaa ataactctat tggagataaa gttgagagtg agataaaaga
    12421 tacattgtca aatgtatcaa taaatagagt tggtggttca gatagatata gtacatcttt
    12481 aatgatagca aaagaattag taaaaactaa tccagtagaa aaactatata taacaagtgg
    12541 tacaggtgaa gcagattctc tttctatagc ttcaaaagca ggagaagaaa agcaaccaat
    12601 agtattagta tcaaaagata atgtaagtga tgaagtttac aattggatat cagatttaaa
    12661 agtaaaagat gcttatttta taggtggtaa tctaagtata tctgattcag taataaataa
    12721 gctggataag gtcattacaa atgatgtatc taaaaataga atagctggag aaaatagaga
    12781 agaaacaaat ggaaaagtaa tacaaaaatt ctatctaaat gctgaatatt catcaatgtt
    12841 tgtaagtaaa agtaatcaat tggtggatgc attaacatca ggtcctttag cagctaaatt
    12901 aaaatcacca gtagttatgc ttggaaatag tgtaacatct gctcagaaaa ctgctttaga
    12961 gcctaagaaa actactctag tatacgaagc tggagatggt ataaatcaaa acacattaaa
    13021 cactttctta aacttagtta agtaataaaa aagttaattt aaaatacaga gtattttata
    13081 aatgtagatt aaaatgaaaa ttatcatgat aaattagaaa ataaaaaaga actatatgca
    13141 ttttgtaatc aagtgtacac agcaacttga aaataattat gcgatatagt tcttttttag
    13201 taattaatct tatacttttt aataaacttt atgttgaatt ttttattgtt taaactctat
    13261 gtcattaaat ataaaatcgt gtaatatgtc taaagtatct gggtcaaatc taagaaccca
    13321 tccagctttt ccatatatac cacctgtact gtgaatttca tcatcaatag gaaattcaaa
    13381 ttgcttaata tttaagtcgc ccatttttaa aacttgagct cctaaagaaa gtattgcatt
    13441 aggcttcatg ttagtcttaa catatggaag aactgcatct aataaacctg gatatttagt
    13501 aacaggtaaa gtttccgttt tcttgattat agcttgtata atctgtctct gtctgccatc
    13561 tctagcaaag gctgtatcgt tgtgtctgat acgtgcaaaa gatagtgcct gatatccatt
    13621 tagagtctgc tttccagagt ttctaatgta ttgtatgcta cctttatcat cacttttatt
    13681 ccatttataa gtttcaggaa taaatttatt tagttctcgt atttctcctt tttcaacagt
    13741 aacctcaacg ccaccaatag catcaattat atacataaat gattcgaaat taacacaagc
    13801 ataattttga atatcaatat taaaattctc ttcaattgtt tgtattaata aatcagcttg
    13861 tccataagca taagcatgag taagtttttg tttaccatga ccagggatgt ctacatagct
    13921 atcacgagct aatgatgtaa gtttgatatc attgtgtttg ttatcaatag taagtatcat
    13981 catagcatct gaccttgaag aatcttcatt tggtctagca tctgttccca taagtagtat
    14041 gttaattatc ccatcttcat ttttatggtc attgttatcc aataaatcac tacttatgct
    14101 cgagtcatga atagcagata atttataata aaaatatcca tagacactta tagggaatat
    14161 tactaccaag aaagccagta gtataacaaa tttctttaat tttgacaaaa gtaccccttc
    14221 tttcttcttt ttcctgtata ttttttaata gcatacactt aattatatta aagtattgag
    14281 atatattcaa tacttgtttc agttacaaaa aaaagacaat gatataattt ataagaaaat
    14341 ttatcgacct atatatatag ttaaaagtat atataatata ttttttaaaa gtaatttata
    14401 ttttaaaata aaaacacacc ccataaatac aaagtaattt gcatttaaag aggtatgtat
    14461 ttatcatcaa attattggtt tgttttggaa tttctaatct tcaaccataa tatctttaaa
    14521 tatgaaatca tgcattgcat ctagttcata ttcctcaaaa ggtattacat agcctgcatt
    14581 acctattttt ctaccatttt cagtagaaag aggaaactcc atagatttca aatttaaatt
    14641 tcctatactt aaaagttctt ttcctaaaga tattatttca ttaggattca tattagtttt
    14701 tacatacgga agtattgtgt taactagatt aggatattta gtgactggta aatccttaac
    14761 accatttatt aaactctgta taacacttct ttgtcttcta tctctttcat ctgtgctatc
    14821 attttttctt atacgagaaa atgcaagtgt ctgatatcca tttaattttt gctcaccaga
    14881 atttcttata tatttaagag aacctttatt gtcattttta ttccatttat aagtttcagg
    14941 aataaattta tttaattctc ttatttcact cttatcaaca gtaacagtaa ctccacctaa
    15001 agcatcaact atatccataa aagagaaaaa gtcaactacg gcgtagtttt gtatatcaag
    15061 ttggaagttt tcttctatag tttctattaa taagttagct tgtccatata cgtaggcatg
    15121 tgttaatttt tgttctccac gtcctggtat attaacataa gtatctctat ttaatgaagt
    15181 tagcttaaga cttttatttt tattatcaat agtaagtatc atcatggcat cagaacgaga
    15241 aacttcttct cctggtcttg catctgtacc taacaataat atgtttgtga tattttcttc
    15301 gtttttatag tcattactac taagcgcctc tgtatttata ctatcatctt gtatagtttt
    15361 taatttagta aaaacatatc catatatact aacaggaaat gctataacta aaagggctag
    15421 aaatataacg aactttttga gtcctgacaa taatatcccc tactttctaa attttttaat
    15481 tacacatagt taattatatt aaaaatttgt tacataagca ataaaaaaca caataaatta
    15541 gcataagttt gtcataatat aattattttt atagtatttt atagaagaaa gtgtgtagtt
    15601 attattgatt ttattggaat ataattgtat gaagacttaa atttttataa actgatgtgt
    15661 atattgaaaa aaatattttc ctgaatgtag ttatagcatc ttatgaaagg tgcaaattgt
    15721 aatttaaaat ttttagtgta taataagaat tgaaaattca aaccgataaa aattaataaa
    15781 aaataattat aaattaataa tttgggggag gaaatgtatg ataaaattaa tagcaacaga
    15841 tttagatgga actttgttag atgaaaagag cgaaataaat ccagagtttt ataaagtatt
    15901 taaaaaatta agagagagag ggataatgtt ttctgctgct agtggcaggc agtatcaaaa
    15961 tcttataaaa aaatttgaag atataaaaga tgatatgatg tttatatcag aaaatggaac
    16021 actagtagta tataaaggaa aagaaatatt atcaaatcct ttaaataaag aattagtaaa
    16081 tgaaatcata gagacaacaa gaagtataaa agggaaaaaa attgtaatga gtgggaaaaa
    16141 atacgcttat atagaaagca aagatgaagc gtttatacaa gaggtcagta cttattatgc
    16201 aaagtttaaa attgtagaag atttgacgaa agtagaggga gacatattga agatagctgt
    16261 atttgacttc aaaggtgcag aacataataa taatatctac tttgaaaagt tttctgatag
    16321 agctcaagta tgtatttctg gagtggagtg gcttgattta actgcaaaag gtgcaaataa
    16381 agggagtgcc ataaaaaaag tacaaaaaat gttagatata aaatatgaag aaactatggt
    16441 atttggtgac cagttaaatg atgtggaaat gatgaaaagt gcctatcata gttatgccat
    16501 ggaaaatgca aatgaacatt tgaaacaaat tgctagattt agagcaaaaa gaaatactga
    16561 aaatggcgtt gtagataaga taaaagaggt tataaaaatt ggatagtcat atgtatagat
    16621 gaaaaagatt attttgaaga aatcaaaaaa atatcaatgt aattttgata aataagttta
    16681 tttatgcgaa aattacattg atatttaata aacatcaata atagatattt atttttttat
    16741 gatattcagt attttgtttt ctatttgagt tgcattttca gcagaaatta aataaacata
    16801 tctacctgcc ttctcaatta tagtattatt tgctatttca gaattgattt tttctccatg
    16861 tccttctcca aaaggtgctt gtatcatatc ttttttataa ttttctagag ttttatagat
    16921 tttatctacc tcgtcagttt ttataacgat aatatcttct agagataatt tttcagaaga
    16981 attaattaca aaaccttgaa ttatgtcttc ctctacatca ttaaaatagt taaaatcctt
    17041 tgcatcaaag atttttgatt cctttataag taaatcagaa gattttaatg ctttttttat
    17101 ttttgatgta gaaacgtttt tgtaatcacc acttgaagaa caactaacca ttcctaatga
    17161 taagattatc gaaaaaaaca atattaaaat ttttttcatg ataaacctcc aagtttttta
    17221 aactctgtct taaattagtt tactacataa ttatataaaa ataaatgtat ttaatgttac
    17281 agttttgatt aataatgtaa tattttgata ataataccta ttgagaggtg attagaaatg
    17341 agaataccaa aacatgtagg aattataccg gatggaaata gaaggtgggc aagtcaaaat
    17401 ggtatgacaa aagataaagg atatgaaagt ggaatagacc ctggactaga gtcttataga
    17461 ttatgtagag atttaggctg tgaagaggtg actttttatg gatttacaac tgataataca
    17521 agacgtccat cagtgcagac aaaagctttt acaaaagcat gtattgatgc tgcaaatata
    17581 ttaatagatg aaggtgctgc tttattagtt gtaggaaata caaaatcgcc aatgtttcca
    17641 gaagaattat taccatatac taatagaatt aaagccaaag aaggtcaaat aaaagcaaat
    17701 cttctggtaa attatggttg gtattgggac ttaaataata tatcaggagt agaaaatgta
    17761 aataaaaata atatacagga ttacatacag tcatttgatg tatccagact agacttgata
    17821 atcagatggg gtggaagaag gagattaagt ggtttccttc ctgtacaatc aatttatgca
    17881 gatttttatg ttatagataa ttattggcca gattttaaga gtgacgatat aaaggacgca
    17941 tttagttggt atgatacaca agatgtcact ttaggtggat aattgaaaat attctgattt
    18001 aaggttgtag agtgttttaa attattgaaa aaaaaacttc ttgatggtaa aataacacta
    18061 ataatatgta aaagtgtaaa aatttatacc aagaagggtg aagaaatgtc aaaaggcaat
    18121 aataacaata attcaagaaa caaatctaaa aagaccagtc atctgaatag aaaaaagcga
    18181 aaattaaata agaaaaagtt agcagtgttg atttgcttta cagttttatt tttatttatt
    18241 gcatttaagg ctactcaagg tgtagtagct ttggtaaaaa gtatggataa aagtaataaa
    18301 actaatcaac aacaaaatgt taactcagaa caatttgacc ttggtaatga agaggaaaat
    18361 aaaaagaaaa aatatactgt atttatagac ccaggtcatg gaggcaatga taaaggaact
    18421 gaaagcaaga ccagtaatag atatgaaaaa gacctaaatc tacaaattgc aaaaaaatta
    18481 gcaaataaat tatctaaaca aaaggatatt caagtagtag tatccagaac tgatgataca
    18541 tatatatcat taaaggatag agctatctta gcaaataata gttctgctga tgtgcttgtt
    18601 tctattcatt taaatgcaga gaaaaatggt aatacagcaa caggtataga aacttggtat
    18661 aggaataaag ctacagatgg ttcaaaagaa cttgcacaga cagtacaaag tactatagta
    18721 tcctatgtta aagttagaga taggggaata gttgaaaata actttgaagt acttagagaa
    18781 tcaaatatgc ctgctatatt aatagagtgt ggttttttaa caacaccttc agaggaacaa
    18841 aaaataataa atgaaaaata tcaagaccaa cttgcggaag gaattgttca aggtgtactt
    18901 tcatacctag attctaaagg gaataagtaa gttaacttta ctttaatgtg aggataaatt
    18961 taaaagttta actgtgtaaa ttgtattaac tttatttcgt aatgttgcaa acattgtttg
    19021 aatttagaaa ctatgaaatt agaaattatt ttatctatat ctaatttcat agtttttttt
    19081 gcaaaaaatt tatagttata aaattttaaa aaataaattt agtataatgt aatgtagtta
    19141 tttatatgtg attttaactt gcattgattt gctatcaatt gtgctttata attagtatat
    19201 ataaagttta actgtaagat aatttaaaaa ataggggaat ttatatgaat aaaaatagca
    19261 tgacaaaaat ttacagttta aataaaataa tttttattat aattggaatt ttaggaatag
    19321 ttttactcac aagacatatt gaggtagata ttaaagtttt aattttaatt ttattaacct
    19381 tgtttagtat aaatgtattt atttcatatc ttaaaattaa gttgtatgag gataaaatta
    19441 atttaggatt gataaataat tcagataagt ttataaatat tactaaagat gagaacttcc
    19501 taaaacatgt tcaaaattat attatcagta atgaaaaaga aaactgtgta atggcttgtt
    19561 ttgatttatg tagactcaaa cttataaatg atatatatgg ttatgagcta ggggatgaag
    19621 tgttaaataa tattttaagt aacttaaaaa attattttgg aaaagaagct atttatggaa
    19681 agttaaaaag tgatgttttt gtattaataa taaagcttga aaatagggaa cagaagattc
    19741 cttatttagt aaatcttatt aagaataaaa ttgtgatact aagtcagatt gacagtttta
    19801 aaatggatat aaatattgag gcttctattg gaatttataa atttaacaat aatgaaattg
    19861 atataaaaaa agctatagat aatgctgata tggcaaggct taaatcaaaa ggactaaagc
    19921 acatagagta tgtagaattt gataatgcta tggaagaaga aatacaatca attatgaaaa
    19981 tagagagaga tttattcttg gctattaaaa ataaagagtt tgtaattcac tatcaaccta
    20041 aagttgattc aagtacaggt aacattatag gttcagaggc attgataaga tggttgcacc
    20101 catcattagg catggttgga ccaaataagt ttatacctat agctgaaaaa aatggtctga
    20161 taaacaatat tggtagatgg ctaattcaag aagtttttat taccattaac aagtggattt
    20221 cagaaggtat aaatgtctta ccagtctcaa taaatctttc tagagtagaa ctatataaaa
    20281 atgatttagt tgattttttt aaactgatgt ttaatacata taatattcca aaagaactta
    20341 tagaattaga aattacagaa acgacagcac taagagatgt aaaatttata agtgaaaggc
    20401 tttatgagat taaatcttta ggtatgaata tatcattaga tgattttgga gtaggtaatt
    20461 caaattttat caaccttaag gggataccac tagatattat aaaaattgat aggtcactta
    20521 tattggatat agttacaaat acaaaaacaa agtttatggt gaaagcaatt gttaaccttt
    20581 cacatgattt aaacgtaact gttatatgtg aaggggtaga ggatatgcat caggtcaaag
    20641 tcttaagtga actgggatgt aatttcatac aaggttatgt attttttaaa cctttggatg
    20701 agatgaatta taaaaaactt cttactgacg gaagttatat aaatctgaaa gatactcttt
    20761 tagataaatg catgacagtt gaggaggagt aaggatgatt tcagaagatg tagattattc
    20821 aataagaatc ataagagcta tatttaataa tggagaagat aaaccaatag atgctaaaat
    20881 gatattaaaa agtgaagata taccaatact aacactatac agactgctta gaaagctttg
    20941 tgcaaacaat attcttactt ttaacaaaga agatggcaag acatacatgt taaatgtgtc
    21001 attggataca ataagtctaa gaactattgt agaagtaatt gatggaaaaa tatatataaa
    21061 taaatgtacg agatatgtat ctaattgcag taattgctta aaaggttgta aagtaaatcg
    21121 tgaattgcta gaaatagaaa aagaaattta taaactttta tcgagaaaat ctataagaca
    21181 aatactagaa taaaaaattt tcagctatga taataattgg aggttttcgg ttatggatga
    21241 tatatctcaa gataattttc tactgtctaa agagtatgag aatagcttag atgtagatac
    21301 taaaaaagca agtggaatat attatacccc taaaataatt gtagattata ttgtaaaaaa
    21361 aactttaaaa aatcacgata taattaaaaa tccatatcca cgaatacttg atatttcctg
    21421 tgggtgtgga aattttcttt tagaagtata tgatatttta tatgacttat ttgaggaaaa
    21481 tatatatgaa ttgaaaaaga agtatgatga aaattattgg actgttgata acatacaccg
    21541 tcatatatta aactattgta tatatggtgc tgatattgat gaaaaagcta taagtatatt
    21601 aaaagatagc ttaacaaata aaaaggtagt aaatgattta gatgaatctg atataaagat
    21661 taatctattt tgttgtgata gtcttaaaaa gaaatggcga tataagtttg attacatagt
    21721 gggtaatcca ccctatattg gtcataaaaa acttgaaaag aaatataaaa aatttctcct
    21781 agaaaaatat agtgaagttt ataaggataa agctgactta tatttttgtt tttataaaaa
    21841 gattatagat attttaaagc aaggagggat tggcagtgtt ataactccaa gatatttttt
    21901 agaaagtcta tcaggtaaag atttaagaga atatattaaa tcaaatgtca atgttcaaga
    21961 aatagtggat tttttaggtg caaatatatt taaaaatata ggggtatcta gttgtattct
    22021 aacttttgat aagaaaaaaa caaaagagac atatatagat gtatttaaaa tcaaaaatga
    22081 ggatatatgt ataaataaat ttgaaacatt ggaagaactt ctaaagagta gcaaatttga
    22141 acattttaat ataaatcaga gattgctatc tgacgaatgg atacttgtaa ataaagatga
    22201 tgaaactttt tataataaga tacaagaaaa atgtaaatat agcttggaag atatagcaat
    22261 aagttttcaa ggaataatta cagggtgtga taaagcgttt attttaagta aagatgatgt
    22321 aaagttgaac cttgtagatg ataaattttt aaaatgttgg ataaaaagta agaatataaa
    22381 taaatatata gtagataaaa gtgaatatag gctaatatac tcaaatgata tagataatga
    22441 gaatacaaat aaaaggatac tagatgaaat tatagggcta tataaaacaa aattagaaaa
    22501 cagaagagaa tgtaaaagtg gaataaggaa atggtatgaa cttcaatggg gtagagaaaa
    22561 gcttttcttt gaaagaaaaa agataatgta tccttataaa tcaaatgaaa atagatttgc
    22621 tatagattat gataataatt tttcaagtgc agatgtatat tcttttttta taaaagaaga
    22681 gtatttagat aaattttcat atgaatatct agttggaatt ttaaattcca gtgtttatga
    22741 taaatacttt aaaataactg ctaaaaaaat gagtaaaaat atatatgatt actatcctaa
    22801 taaggttatg aagataagga tttttagaga taataattat gaagagatag agaatttatc
    22861 aaagcaaata atatcaattt tattaaataa gtctatagat aaaggaaaag tagaaaaatt
    22921 gcagataaaa atggataact tgataatgga ttctttaggt atataagcag ttgtaagtat
    22981 taaaaaatta taatctttta attgtttatt taaatttaga aataaaaagt tagccatata
    23041 aaaaatatta aaaatatata cttttcaata tttttttgat aaaataagaa tgaatttgtg
    23101 caattttatt tttctccaat aactaaaaat agttttttga attaatattt gcttaagaat
    23161 aaaaatcaga aacgtttttg atatagtagg tgataatatg aaaggattag ttttagaagg
    23221 tggaggaaca aaaggagcct accaaatagg tgcatataaa gctttaagag agcttggtat
    23281 agagtttcaa ggagtaactg gcacatcaat tggtgcttta aatggagcat atataattca
    23341 aaatgatatt gaagtaatgg aagatatttg gttaaattat gactatactc attttatgaa
    23401 tattgataga gaaacctatg agaggtttaa aaatgtagat ttcactacta aaaatctcaa
    23461 tgcagtgttt gagcttataa ataaagctag aaaaaatgaa ggtatagata taagcccatt
    23521 aagacaatta atggagacaa cattaaatga agacataata aggaaatcaa aaaaagactt
    23581 tggacttgtt acggtctggt gggataaaaa aattaatcca tatccattgt atatcgaaga
    23641 tatacctaaa ggaagattga ttgattattt aattgctagt tccagtttgc ctatttttca
    23701 aacgaacatg atggatgata agttgtatct tgatggaatg ttttgtgata acatgccaat
    23761 aggactcttg gaagacaaag gttatgaaga tgttgttgta attaggttga ttgatgattt
    23821 tattgggaaa atgaatctaa atcgacatca aaatataaat ataaaaacta taataccatc
    23881 agaatatcta ggaggttctc ttaataaaga tagagataat gtagaaaaaa acatccgact
    23941 aggttactta gatactatga aagcatatga aagatgcact ggaattaagt attattttga
    24001 tgtagagtat aaatataatg aagaatattg ttttgataaa tttagaagta tgagcaatga
    24061 aacaatacaa tatatctgta atttattgaa tataaaaaga gatgcttcac ttagaactgt
    24121 tatggaaagt gtaataccaa agcttggtga ggtgcttgga ttgccaaagg atttttcata
    24181 taaagatttg ttttactgta tatatgaaaa gaaacttgaa gaaaataata taaacaggat
    24241 aaaattatat gattttaaca aggttataga tgttgtaaat acaaatattg attctaatag
    24301 aaatttagct tctaattttg aagttagacc taaaattagt attaaaaaga acaaaaacac
    24361 aaaattattg acaaattgta ttataaaaga cataaaaaat caaagttaaa taaaaaacaa
    24421 aaaaaaattt gtaattatac tcgaaaaaag tgtatattag tagtataata tttttgtagc
    24481 actagtggga acaaaaaatg accataggac aaaaaagtac cacttagtac cattaaagta
    24541 aaaaacagga aaacaatttt aaaaaatata aaatgtaaag tttataggag gatttaaaaa
    24601 aatggaaaaa gtagttagta tcaaaaatgc aagtggatta catgctagac cagcaggaat
    24661 gtttgttaag aaggcagctg aatttaaatc aacagtagag gttgtagcaa aagacaaaac
    24721 tgtaaatgca aaatcaataa tgggaataat gagtttaggt ttagctcaag gagaagaatt
    24781 aaagttagtt gtaaatggag aagatgaaga agtagcttta gctgcaatgg ttgaattagt
    24841 tgaaagtgga tttggagaat agatataata atttttaaaa atttgatatt tagaatctaa
    24901 tattacttaa agtaaagtaa cagagaagta ttaaacatat acagaccaac atttgtagat
    24961 atttaatttc tttgttactt tcatgtttat ttaatcagaa gattaagact attgttaatt
    25021 gggtataaaa atataaatat tttagaaaat gaaataagat atttttaatc ataaattcag
    25081 agtaaaaata caataacaaa tagtttataa aattttataa aaaattataa gtaaataaaa
    25141 ctataaaaat gtaaattatt tatataaatt tataaagttt atgtgctaga tgatattttt
    25201 taggaggtag ggttatggct tacaaaggaa taggtgcttc tcctggtgtt gctttaggga
    25261 aagcgttagt agttgaacat agtgaattag taattgaaaa aaaatctata gataatgttg
    25321 aagctgaaat tgctaaatta gaagatgcag ttgcagtttc taaagaagaa ttagtaaaag
    25381 ttaaggaaaa ggcttctgaa gaattaggag cagaggaagc agaaatattt gaagcacatt
    25441 tattagtttt agaagaccca gagttaattg gttctgcaat agataaaatt aaaactgaaa
    25501 gtgtaaatgc agagtatgct ttaaatgaaa taaaagagat gtttgttagc atgtttgagt
    25561 ctatggacaa tgagtacatg aaagaaagag cggcagatat aaaagatgtt acaaatagaa
    25621 tacttagaca tatattagga attaaagttg ttgatttatc tgctttaagc gaagaagttg
    25681 tattaatagc acatgattta actccatcag acacagcaac tatgaataaa aaaatggttt
    25741 taggattttt aactgatata ggtggaagaa cttctcatac tgctatcatg tctagaactt
    25801 tagaaatagc tgcaatcgtt ggattaaatg atataacttc aaaagttaag gatggagatt
    25861 ttgtggtttt caatggagac acaggtgaag taatcgtgaa tcctgatgaa gagactataa
    25921 ataaatatac tgaattaaaa gctaagtatg aagatgagag aaaagcatta cagctattaa
    25981 aaggaaaacc atctgtaact ttagatggaa aacatgtgga attagctggt aacataggaa
    26041 cacctaacga tatagaaggt ctaataaaga atgatgctga aggtgttggt ctttatagaa
    26101 cagaattttt atacatggat agagattctt tcccaacaga agaaatacaa tatgaagcat
    26161 acaaagctgt attagaagga atggatggaa agcctatagt tataagaaca ttggatatag
    26221 gtggagataa agaattaagt tatttaagta tggaacctga aatgaatcca ttcttaggtt
    26281 acagagcaat aagactttgc ctagatagaa aagatatatt taagactcaa ttgagagctt
    26341 tatatagagc tagtgttcat ggaagattaa gaatcatgtt cccaatgatt tcatctttag
    26401 aagagttgtt acaagctaaa gaagttgtaa aagaagtttt agcagaactt gattctgaag
    26461 gtgtgggtta tgctaaagat gtagaaattg gtatgatgat agaagttcca tctgctgctg
    26521 tgatatctga tgtattggct aaacacgtag atttcttctc tataggaact aatgatttaa
    26581 ttcaatacac ttgtgcagtt gatagaatga atcaaaagat aagctatctt tacaatcaat
    26641 ttaatccagc tgttttaaga cttataaaga ctgttataga caatgcacat aaagaaggca
    26701 aatgggcagg tatgtgtgga gaatctgctg gagaccaaaa aatgatacca atacttttag
    26761 gtatgggatt agacgagttc tctatgtctc caatatcaat acttcctgct agaaagttaa
    26821 taacttcagt taaagagtca gatatgaaaa aattagctga tgatgtactt aatatgggta
    26881 ctgctgaaga aataaaaagc tatatagaaa agacttttaa tatataatta atgttatata
    26941 gttactaaaa ttcatttttc taaataacaa aattatattt tacgaataaa aaaactatag
    27001 tatatcatat atactatagt ttttttgtta tataaattac gtatcaaaat ttgtaaaatg
    27061 aatagatata attactaaat atgtgatagt attggctata ataggatata aaaaataata
    27121 ttgtaaaaaa aagtttatat ttagtaatga aaatttaacg ttttacttga aattatgtgt
    27181 tttgtaatgt attattaagg ttctaatagg aacattttca tcaatttttc tatagtgggg
    27241 gtaggaatta tgaggtacaa aaaaagaaat atagataagt caagtgaact ttcatttcaa
    27301 tctctagcaa aatattttat aactttctat atagtaatta tattaattat tctttctatg
    27361 ttttgtataa atacaatatg ggttatgaaa aaagataatc aagatttatt atctacaaca
    27421 tcaaatcgta ttgaagatag ggtaggagaa acaattaagc tattgaactc tttgagtaaa
    27481 gataattaca taatagataa tagtgtgaat ggcatagata aaagtaaaga actttcaatg
    27541 tatagtgatg aatttgggta tatgatgata tgttttgttg ataagaatat aattgtgtgg
    27601 gatgaagaag gtggtaatat tagtctagct ggtcgtgatt atatgcagaa actttttgca
    27661 acaaaaaaat atcaagttac agatagtttt gcagcagggg ctgatggaaa aactttaaac
    27721 tacactattg catcacctat aataaagaat ggaaatgtag atggttgtgt atttgcagca
    27781 atttactttg atgagataaa ggatatactc aaacaaggaa aaggtcaaca gcaacagaat
    27841 ttcatattat ttggaagtga aaatcaaata atgaatttaa caagtgatga aactgcatat
    27901 ggagagaagt atatgaagtt atcgcagaaa acaaaatatc ttggaaccaa tgcaaaaaaa
    27961 gtagaaaagg atatgtttaa taataaatca ggtgattatt gggcttttga aaatggaaaa
    28021 ttatacttta tgtcctataa accaattaag aacacaaatt ggagtttatt ttgtaaagtt
    28081 aatttcttag atatttttgc attaaattta attcctatgg gagctattct atctgttata
    28141 actttagtat ttattatttt gatttgtatg gagaaaagct tcatgaaaaa acgaatggaa
    28201 gttattgata tgcttttagg ctctgttcaa gaattagaaa aacgtatata tcaaacagaa
    28261 agacctagtg aagtagactt taaagaaatt attcagctca caagtaaagg tctgactgat
    28321 ggattaactg gtgttgtaac acgtactgta ttttttgacc aaatttataa tcgtgttgaa
    28381 atggaggaaa atgataaatt atctgtaatt tcatttgttg atttagatga tttgaaatgt
    28441 attaacgact tatatggaca tgaaattggg gatatggttt tgaaaaatgt tggatatgta
    28501 cttcgtgaat atgagataaa atataatggt ttaattgggc gctatggtgg agatgaattt
    28561 gttatgttgt tatctggttt tacatcgaga gaagaggtgg aggatttatt ggatgagatt
    28621 gctattcgct tacatactga agtactaaca gatgatggta tcattcaaac tcattgtagt
    28681 gttggagctg tagtatgtag tgtaaaagac aataaagata tagataattt attaaaacag
    28741 gctgatgaag ctttatacta tgttaaacgt aatggaaaag gtaattatca tttagtttaa
    28801 tgtatgtgga aggagtttat atcatatgaa aaatgtatct aaaaaatttt ttgtatgtac
    28861 tattattgta ttaataacat ttttatgttt tagtaaattt gctatttatg tttttgacaa
    28921 acaagaaaag aaagaaacaa aagtagtaga aaacatgtta aatgcctaca agaataacat
    28981 tattttaaat ctgactgaaa aatttaatta tagcaaagac ttgacatcag ttttagtttc
    29041 aaacaattat tctatagata aattaaaacc tattgcagat gaaattctta aaaacaattc
    29101 ttgcatatat atttcagttg tagaaaaata taatgtagct gcattttttt ctaattctgt
    29161 caaaaaagat attatcaata ctccaataca ggaactgaat tattcttatt cattagcaaa
    29221 ttctatcaaa ggattagtcg tagaaggtcc ttctaaagac cagttttcaa atggagatgt
    29281 gtttttaatt actaatccta tttataaaaa tggagagtac tggggagaaa ttacagtagc
    29341 tttagatgcc aaaaaagttg tagattcttt taatttaaat aaattaaaag aatctggatt
    29401 tgagtatgaa ctttggcgtg tacatctaga taatggttca aaatctacaa tagaaatttc
    29461 tactaaagat tttaattttt ccaaatcaca tgaaattaag tttaaacttc cgactgtttg
    29521 gactcttagc attgtgtaca aaaatggatg gaataataag aatatagatt ttattgtatt
    29581 tgttatattg ttaattattt ccatattaat aggtgtgatg acatttattt acattgaaaa
    29641 gaagtcgatt agtaaggaat taaatcaaca gagtcttaaa aatttagaaa ctggtatttt
    29701 gaatagagaa ggttttttaa ttaagttaca agagcatctg aatagaaaaa ataatgaaat
    29761 agtgttgctg tatatatgta ttactaatta tagtaaattt gctccagtta tgagctttga
    29821 aaaaagacaa gattatctta cacatatagt aaaaaaccta gataattaca taaaaagttc
    29881 tcattttatt gctcgtataa gtgaggaagg ttttgttcta gctttagaag aaaattgtga
    29941 taaaaatgaa ttgcttaaca ttgaaaaagg gatttcctta gagcttttac gaaaaattaa
    30001 agtagaaaat aaacaagtat ttttaacgat tggttatggc tcatctaggt gtgttgatga
    30061 tagaaaagat gcagaatctc tgttactttc agctattgaa gattatgaga gaagatttcc
    30121 agcaatgtct cctattcatg attttactaa aaagtgtgaa gatatgcttg atgaaaagaa
    30181 acagattgta tttggtgaat atccagattt agaaataaac aagttgtcta aagtaatata
    30241 caaatattat aaaaaagtac agcgtattat gtataaagat tataatattg atattggaaa
    30301 tagacgaggg tatatgcgtg atgtcgaagt attaattgat tataattctg agagaatgtt
    30361 atacttattt ttaatagaca tatgcaagtt tggaaaattt aatgaactgt tttctattga
    30421 aataggagat gttattttaa aagaagttag taacaaatta aaaacaattt tttctaatta
    30481 tctatatcgt attaatggag atgtattttt aggcatttca atagataaag aatcttactt
    30541 agatacttta cataaggtta atgaagtatt taatagttct ttaagtgtag aagatgtact
    30601 ttttgatata aaatgtaata ttggtatttg tcaatatcca tatcatggtg aaaatccata
    30661 tgaccttctg gaaaaggtac aaattgcatt ggagtatgca aaaaaggatg tcaaaagtaa
    30721 tgttaaagtt tatgataagg aattgacaga agagatttac catgaaaata atattattaa
    30781 ggatttaaaa aaaggtctgg aagaacaaac actagaagtt tggtatcagc caatttttaa
    30841 tgttagtaaa aactgttata taaaagctga ggcactaatt agattgagaa ataaagaggg
    30901 cggttattat tctgcctatg aagttattac ttatgcagaa aagcatggac ttattaagga
    30961 tgtaggtcta tatgtactaa aaaaggcttg tgatgtaact acaaaaataa aagataaaaa
    31021 tatagatttt gaacaaatgc aattaaattt atctgttcag cagattgtac ataagcagtg
    31081 tgcaaatgac atattatcat gtattgagaa ttgtggtcta gataaaaagt atatttgtgt
    31141 tgaagttaca gaaacagtac ttatggaaac ttttgaaatt gtaaatgtta ctcttgataa
    31201 actaaaaaaa gaaggcatta gcatagcttt agatgagttt ggttctggat ttagtagtat
    31261 aaattatctg gcaaatttac ctattgaaaa tttaaaaata gataaggaat tagtagaaca
    31321 aattacctat tctaaaaaac aatttgaatt attaaaaact atagttcaaa ttgctaagat
    31381 taatggcatg gatattgtag cagaaggtgt tgaaacaaaa gaaactctgg atttagttgt
    31441 aacttcaggt gtgaatttga ttcaaggtca ttatttttca gaacctttaa gtgaagataa
    31501 atttattgaa cttatgattg aagaataaag gttaataaaa taaagattta aggtattgaa
    31561 aaataattaa aagtatttaa taatagaatt agggaagaat aagtttataa gtaaaaataa
    31621 ttgattagta gttaataaaa taaatgtgat atccaaataa atcctaaatc taatttgagt
    31681 tttaatatag atagtctaaa gtttgattat taaagattta attgtaagtt gttacagttg
    31741 atgatattga ttagagatta aagtttagag tagaaagtta ccttaaattt aaaaatgcaa
    31801 gataacccaa tctaaaaatt ataatcactc gataggttta aggatttatt tgtttattat
    31861 aaataggagg gtgtctcaaa atgaactttt tagtttatga ggcactctct tttatataga
    31921 attaaatata ttttattatt tcaacaatga aaaagaagct tatctctatt ttgagacagc
    31981 ctctttgtat actattatta atttaatcaa taacataatt taaaattata ttattagtta
    32041 agatttcctg ctttattagt aaataattct ttaatagcat tgtttctgga aactaaatcg
    32101 ttatcagagt tgtttgtttt tttcataatc actgaataac gttttttatt tataaaaaat
    32161 attaaaatct tatcatcatc aaaattgtat tctttatatc tgtcaataga ctcataacct
    32221 agatttagaa tgtttttgtc ttttatacta tctacatcta aaatatatga tgggtcagcc
    32281 tttagtaata tattgattaa acatttttct tcaccagcag agaataactc catcttactt
    32341 gatatagatt tagattgctc tgaagttatt tttgcaggaa taaggttgtc attatcatct
    32401 cttagaagat aaccatgtgt gtcttgttga tatactaaat taaccttttt cttaggaaca
    32461 ctaatcattt tatctaaatg tacataatga tgattttcaa caaaaccttc atttaatatt
    32521 tcaacaaagt tattaatttt acctaggcaa aaagattcta tagattcttt acagaattta
    32581 tttgtaaatg gtattatgtt tacgttttcc tcgtctgtat tccatgctat agcataatcc
    32641 aacgaatata cttcttcctc tatatctgca aaattatatt gtactatgtt tcctttcaaa
    32701 attactcgac ctccatctta taatatattt aatatacttt ataaaactta tattatattt
    32761 aaataatatc ataaattgga taaatatgat atagtaaata agaaaaaatt tgaaaaaaat
    32821 cactataaat gagtaataaa tataaatagt gtatactaat gggatggaaa atgtccacta
    32881 ttaactttat taccccacat atataagata aaattattaa tataaaatat aatctatcga
    32941 caatgaatag acttttaaat aaacttaata taaaattaat taaataagtg cttaaaaacg
    33001 atttacttta atgatagaat catattaaag gaggataatt ttatggatat aaagaataaa
    33061 attaaatcta tatttttacc agaaaaaaat gactatttag atgatgaaga atttgagtat
    33121 gatatagaaa ataatgaaga agatttaaag gaagataaca aagtacattt aaatgattta
    33181 agtagagtaa aatatgatta cagagagtta aaagacatag aaaaccaaac agaagagata
    33241 tgtctgctag cagtaaagca ggatggtact ataattgagt ttgtaaagga caagacttat
    33301 aaagtatgta tggaagcagt aaaacagaca tataaatctc ttaagtatat aacaaatcaa
    33361 aatgaggata tttgtataga agcagtaaaa cagaactaca gagctttgta ctacataaat
    33421 aataagacag aaaatgtact aattgaggct ataaaaaatg catcaactta tgatgtcatg
    33481 gaagtattta aatttgtgga agagcaaaca gaagatgtat gtctagcatt tatagaaagg
    33541 gcatctaaaa atgatgttgc agagatatta aaaggaataa aagagcaaac tccagccata
    33601 tgtttagaag ctgtaaaaaa agatggaaaa tctttagctt atgtaaagga acaaagtaat
    33661 agtatatgtt tagaagctgt aaaagaaaac tacagtgcac tatcttgtgt aaaagagcaa
    33721 actgaagaaa tatgtataga agcagtaaaa cagaatgact ttgcattgta ttatgtaaat
    33781 gaacagacag aaaaaatatg tatggaagca gtaaaaagaa gttatatggc tctacagtat
    33841 gtaaataagc aaacagaaga gatttgtttg gaagcagtaa gaattgatgg aagagcatta
    33901 cagtacgtaa aagagcaaac agaagaaatt tgcttggagt cagttagaca aaatggaaaa
    33961 gtactgcaat atgtaaaaaa acagactgaa aatatatgta tagaagcagt aagaggttca
    34021 tttgaagaac ttgaaataaa agaaatatta agttatgtaa agataccaac agaaagaata
    34081 tttgtagaag cagtaaagca aaatggaaaa attcttaaat atgtagaaaa tcagacagaa
    34141 ttaatatgtt tagaggcagt aagagaaaac tataatgctt tagcttatgt aaaggaacaa
    34201 acagaaaaga tttgtttaga agcagttaat caaagttatg aagcgcttaa atatgtgaaa
    34261 gaacaaacag aagaagtttg tctaaaagca gtaaaacaag attatagaat gttgaaatat
    34321 gtaaataatc aaacagaaaa aatatgttta gaagcagtaa agcaaaatta tagagcttta
    34381 gaatttgttg ataatcaaac agaaaaagtt tgtcttgaag cagtaaaaca gaatagaaaa
    34441 gcactacagt atgtaaaaca aaaacaaagt taaaaggcta aaatatatag aaaatatatg
    34501 caaataaata aaatttgata ttttgtaata aataaaatgg gtatctcaaa aggaactttt
    34561 tagtttgtga ggtactcttt ttatatgaaa taaaatatat ttttagactt ttaacaatgg
    34621 ggaaaaggtt tatttctatt ttgacatagg ctttttatgc atataaagct tgataaaatt
    34681 gttttattat aattgttttg ttatataaat aataagaaga aaattatata ggtctttttt
    34741 tgaccagttt tacattttta acaactagtt ttgtaaagta tattgaattt tctcaaaaaa
    34801 gaatgtactc tatatatgta aaattttttt ggaggtaaaa atgtttaaaa gatatgctga
    34861 aaaaatgaca tctgttttaa tttgtaataa tatgatagat aataatgaat ctaaagtcta
    34921 ttcttatgga tttgaaatat taatagcttt catagttaat ataaccacca tgctgtttat
    34981 aggtttttta tttggtaaat ttacatatgt attatttttt ttaatgtgtt attgtccaat
    35041 aagacaattt tcaggagggt atcatgcaga caattatttt agatgcttat taacctttat
    35101 ttttataatt ttatccacaa tcttaattat agaaaatata aatatagact tatttaaaaa
    35161 tattattatg attattgcaa gtgttagttg ggttggaatt tgtgttctgt gcccaataga
    35221 acataggagt aaccctataa gtgataggga aaagttggtt tataagaaaa ctgctatatt
    35281 tatatctaca gtagtgttat tgataacaat tttaagtctt tctttgagta tatttgtaga
    35341 ttatttcaca tatagcgcat ttgccatgtt ttggattttt gtgatgttag tattaggtaa
    35401 gttaaaagct aaagtataag taaaatatgt atgagggaga gttaagttat gaaaaagttt
    35461 attgtaagat ttatgaagtt tgctagctca ttggcactta gcactgctat tttgtcagct
    35521 aatagtacct gtccttggat tattcatcag cctaaagtac ccaaagaaat cagcaatcta
    35581 aagaagacaa attaaataca agcacttatt tatacaaaat tatcaggaaa aaagaaatta
    35641 ttatatttta ataagattaa aacaatataa aatcagatac aaaatttatt ttatttattt
    35701 tataggagcc taatacctat ttggtaatat attagtgcgc caatttaggg ggatatagtg
    35761 tatttaatga aatgacttac ggagagtaag tcatttttgt attgtatgta ttttatgtaa
    35821 acttatgata taatgaaggg taaagtttaa ttaaaataat aaaaaacttt agtatagata
    35881 gtaatttagg aggtagagta tgagtatgat acataagttt tctatgaatg gatataatat
    35941 cgttttagat gtgaatggtg gagctgttca tgtgttagat gatgttgcat acgatttgtt
    36001 agatttttat aaagaaaaaa gtaaagaaga aatattagag atattaaaat caaaatatca
    36061 agaagaaaaa ataaatgaag catatgaaga aatattaaat ttggaaaaag agggtctttt
    36121 atatacagaa gatacatatc aatatcatcc aagctttgta catagagagc ctgtagtaaa
    36181 agctttatgt ttaaatgtag ctcatgattg taacttaaaa tgtaaatact gttttgcagc
    36241 tcaaggtgat tttggaggag aaaaagaact tatgagtttt gaagttggta aggcagcaat
    36301 tgactatttg attgctaatt caggaagtag aaagaaccta gagatagatt tctttggtgg
    36361 agagcctttg atgaactttg aagttgtaaa acaactggtt gactatggaa gaagtgtaga
    36421 aaaagattat aataaaaata taagatttac aataactaca aatggtgtac tgttaaatga
    36481 tgagattata gattatataa atgaaaatat gcataatgta gttttaagtt tagatggaag
    36541 aaaagaagtt aatgataata tgagaccaac tttaaatgat aaaggaagtt atgatattac
    36601 attaccacga tttaagaaac ttgtggaaaa aagagcaaaa gataagtatt attatataag
    36661 aggtactttt acaagggata atttagattt ttcaaaagat gttatgcatt ttgcagattt
    36721 aggatttaaa ttaacctctg tagagccagt cgttggagat gagagtaatc catatgcact
    36781 tagagaagaa gatttaccta agatatttga agagtacgaa aaatttgctg tagagtatgc
    36841 agatagacaa ttacaaggag atggatttaa atttttccat tttatgatag acctaaatca
    36901 aggtccatgt gtaataaaga gaataactgg atgtggagct ggaaatgagt atctttctgt
    36961 aactccaaat ggagatatct atccatgtca tcaatttgtt ggaaatgaag aatttaaaat
    37021 ggcaaatata tttgatgaag aaatagtact tccagaaaat ttaaaaaata tgtttagaga
    37081 agctcatgta tatactaaag aagagtgtaa acaatgttgg aataagtttt actgttcagg
    37141 tggatgtcat gcaaatgcga taaactttaa taatgacata tcaaaaccat atgaattagg
    37201 ctgtgaaatg caaagaaaac gtacagagtg ctctataatg atacaagcta agttaatgtt
    37261 agaaggagca accaactaaa tttatatttt aaaggagttg tttatatatg attagagatt
    37321 atttagaaga taaaccttta attgacgaaa gtgtatttgt ggcaaaatca gcagatgtaa
    37381 ttggaaatgt taaaataggc aaagattcaa gtatatggta caatgcagta gttaggggtg
    37441 atgaaggacc aataactatt ggagaaaaca ctaatataca agattgttct atagtgcatg
    37501 gagatacaga aactataatt ggtaacaatg taacagttgg gcataggtct atagttcatg
    37561 gttgtaaaat tagtgataat gtgttaattg gtatgggttc aataatattg gataatgctg
    37621 aaataggaga atatactctg ataggagcag gtacactaat tacatctaat aagaagtttc
    37681 caccaggtgt tttgataatg ggttctcctg gtaaggttgt tagagagctt acagaagaag
    37741 ataaaaaata tattgatgaa tcttatgaat ggtatttaga ggcagcacaa aatcaaaaat
    37801 attagtttaa agagtggttg tttcaaaaca tatttaaatc tgttttgagg caaccactaa
    37861 tttattttat tagattttgt tgatatttta gttttcaaaa agtatttgat taaaccagat
    37921 ataaaatgtc aaaaataaaa attaactgag ttaaataatt ttaataaaat tggtagtata
    37981 tgtgataaaa ttaaatatta aagaggatat aggatattag aatatcaatt ggtgaaataa
    38041 tgtcatatac gataaattaa ggtgtaagtt tttgggtata cctatcttag gagtgaaaag
    38101 atttgagaat aagttataga aatttaaagc gatatagaga aattggatat gttttaataa
    38161 agtatggttt tagttttatt gtagaaagac taaatataga aggaattgcc tataaaatac
    38221 cactatttga cccaccagaa gaaataaaaa atatgacaac tggtgagaga atgaaaagag
    38281 ttttagaaga actaggacct acatatataa aaataggaca gatattgagt acaagaaaag
    38341 acttgttaga ccaggatata attgatgaaa tatcaaaact cagagatgat gtagagaaat
    38401 ttgattcaaa tatagctatt gatatattta aagaagaagt gggtttaagt atagaagaaa
    38461 tattcttaga atttaaagaa gaaccaatag cagcagcttc aattggtcaa gtttatgaag
    38521 gtgtacttaa aacgggagaa gaagtaatcg taaaaattca aagaccaaat atagagaaaa
    38581 taataaaatc tgatttagag attcttagaa ctattgcaaa tactttaaaa gatttaaaaa
    38641 aggattttaa tttagattta gtacagatga ttgaagaatt tcaaactcaa ttaatgaggg
    38701 aacttgatta tacatttgaa gctataaatg caactaaatt ctctaggata tttaaaaata
    38761 gtgatgaagt atatatacct aaagtatatt cagaatataa tactaagaaa attttagtaa
    38821 tggaaaaagt taatggtaca aagttaagtg atgtagaaaa aataaggaga ctaggttata
    38881 acacaaaaac tattgttgaa ataggcgtta ggtcattttt tacacaggta ttatctcatg
    38941 gattttttca tgcagaccca catccaggta atatattcgt aattgctaaa aataagatag
    39001 catatataga ttttggaatg attggaatta ttgataataa aactttaaac caattaaatg
    39061 aaattgcatt agcaggtgta gaaaagaatg ttgacaagat aatatatcta ttgatagaaa
    39121 tggatgcatt aaatggagag gctgatatta agggacttag acaggattta ctttatctaa
    39181 tacattatta ctatgatatt tctatagaaa aaataaatgt aacagatata ttaaatgaac
    39241 tatttaggtt ttttagacag tataaaatag tcatgcctgc acaatttgta actcttgcaa
    39301 agacagttat aacattagaa ggaacaagta gaactttaaa cacagatttt tcttttggtt
    39361 ctatgggaaa agagtttatg aaacatcatt ataagagtaa atttaaccct aaaaatgttg
    39421 ttttaagttc aagacaaaat gtagaagaaa tattactgga cataaaaact attccaaagc
    39481 aattaaaagc aattttaaaa aatatagaaa gaaataatat aaaaatgcaa attgaagatg
    39541 ttaaaatgac gaggttagaa aattgtataa tagagctaac atctcaaata tctttgagtt
    39601 tagtgttggc atctattata gtaggttctt ctcttataat tgcatctcca aatatagaaa
    39661 ataatatatg gataaaattt actgcaatag cgggtttctt tatatccttt ataataggcc
    39721 tttgcttagt tataagaagt attaggtcaa aatacaaaaa agattagggg gaattaaatt
    39781 tgaaaaaatg gatattgaag tataaaggta agatagagga aagtgaattt agcaaaaaac
    39841 ttaatatttc cccggaaatc tgccaaattt taaaaaatag agggatatgt actgaaaaag
    39901 attcagagat atttatgaat ccatctttag attatttaag agaccctttt ttaatgaaag
    39961 atatgcaaaa agctgttgat agaataaagt tagcagttga gaagaacgaa aaaatttgga
    40021 tttacggaga ttatgatgtt gatggtgtat catctacatc tatcttgtgc ttatatttta
    40081 agagtatagg ttacaatgtt gattactata ttcctaatag attagaagaa gggtatggta
    40141 taaatgaaga tgctattaag cttataagct ctaggggatg tgacttgatt ataagtgttg
    40201 actgtggaat tacatcagtg tctgaggtca atacagcgaa tgatttgggc atagatgtta
    40261 taattacaga ccatcatgaa tgtcaaagtg aaattccatc agcctttgca gtaataaatc
    40321 caaaacaaga agattgtaat tatccatttg attcactatg tggatgtggt gtagcattta
    40381 aaatgattca agccttgact ccaaaagaag aatttaaaac tagtatgtat aattatttgg
    40441 aaatagtaac actagcaact atttgtgata ttgttccact tatagatgaa aatagaataa
    40501 ttgtaaaaaa tggtttaaaa tcaatgaaag aaggcaaaaa tattggatta agggagctta
    40561 taaaagtttg tggtgtagaa agtgataaga taggttcttc tcatataggt tttgcaatag
    40621 gtcctaggat aaatgcttca ggtcgattgg gatattctta cttaggagta gagctattta
    40681 ctactcaatc acaagaagag gcagtagaaa tagctagtat attggaagaa aaaaataatg
    40741 aaagacagat gatagaagct aagatgtatc atgaagctga ggaaatgcta aagtctaata
    40801 gcagatacaa tgatgacaag gtgttggttt tagctaaaga gggttggcaa catggaataa
    40861 taggaattgt agcatcaaag ttaactgaaa aatactacaa accaacaatt cttctaggta
    40921 tagaaaatgg ggaggctact ggttcagcga ggtcaataaa aggatttaat atatttgaag
    40981 ctctcataaa gtgcaaagac ttgatgacta agtttggtgg tcatgaacaa gcagcagggt
    41041 tatccttgga ttcagacaat gtagaaattt tagcaaatga aataaataaa tttgcagatt
    41101 ataatttaac tgaagatgat atgatagaga atgtaaatgt tgagtttgaa ttacaagaaa
    41161 atgtaataaa tttaaatctt gtagaagaat tacataagtt agaacccttt ggattaaata
    41221 atcctaatcc tagatttata gttagaaatt atattttaaa agatttgaaa gttataggta
    41281 agaatcaaca acatctgaaa ttaagcatag aaaaagagaa aagctatgaa tgtataggat
    41341 ttaatatgag tcatttaaaa tcaatgtata aagtaggaga caaggtagat gtactattcc
    41401 aattagatga aaataactat atgggaaata ggaaagtaca atttttactt aaagatatac
    41461 gattggctcg acctaaaagt gcaagtaatg acaaactttc attgaaatta atgtcaaaaa
    41521 taataccaaa agatactcaa agcctgtata atatatctgt gtctgatttt gaattatttg
    41581 atggaaatac agatataaat atatttgatt attttgaaaa agatacacta ataatatcta
    41641 attctataaa tggattttat agagcaatgt cagatatatc acttatagat ttggatttta
    41701 acataaatta caatattatt gaagatgtta gcaaaaatac tgataaatta gagcttatat
    41761 tttctcctaa tattgataaa atagacttaa aaagatataa taatattatt ctttatgatt
    41821 atttatacaa taaaggcgaa tattcgtata tatatgagaa taaaagagaa gaaagtgaaa
    41881 ttataaaata ttataataaa acagacctat tatatttaaa gaatgtagtt agtaatatag
    41941 ttccatcaag agatgaattt ataacaattt ataaacaagc actcataaaa aaagaaattg
    42001 atttggatat ggtaaatata agggaaactt ttaatgtaat tccattaaag ttttttacga
    42061 tattaaatgt atttagagaa ttaaatttac ttgactttaa tttaaattat gaaaaaaatt
    42121 ctgtactcat aagaatattg ccaaaaccac agaaaaaatt agacttaaat gagagtttaa
    42181 tactcaataa tctaaaaaat ttagaaaaac aatacaatag cagttattag gaggcgtttc
    42241 ccatggattt aaaaaacttt ataaggaata ttgatgattt cccaaagcca ggcatagatt
    42301 ttaaagatgt gacaactcta tttaaagatg gagatgcatt taaatatgca gtggattcta
    42361 tagttgaaga attgaaagat aaagatgtag atttagtaat aggaccagaa gcaagaggat
    42421 ttttgatggg tacacctgta gcatatgctt taggagtagg atttgttcca attagaaaac
    42481 ctggaaagtt accaggtgaa gttgagagtt atgagtatgg attagagtat ggtacagata
    42541 ctttagagat acataaggat gcaattaaaa agggtcaaaa agtagcaata gtagatgatt
    42601 tattggctac tggtggaact atggaagccg ctgccaagct tgtagaaaaa ttaggtggag
    42661 aagtagtttc tatgcaattt ttgattgagc taaaattctt aaatgggaga gaaaagttgt
    42721 ctaactatga tgttaattct cttataaaat actagtactt ttataatagt tggtataaca
    42781 ccaactattt tcatatatat taaaatttta tacaaaatag gtggttatat gcatgataaa
    42841 gaattacaag aaataattga aaaaataaaa gtttatgcac ctaatgcaaa ttttgaaatg
    42901 gttgaaaaag cctataatct tgcaaaaaaa gcgcatgaag gacaatatag aaaatctggg
    42961 gaaccatact ttattcatcc attagcagtt gcaaatattt taatagagat ggaattagat
    43021 attgaaacta taacagcagg tttacttcat gatgttgtag aagatacaga atatacctat
    43081 gaagacataa aaaaagaatt tggcaaagaa gtagcggatt tggttgatgg agtaactaaa
    43141 cttggtcaaa taaaatatcg ttcgaaagaa gaaactcaat ctgaaaattt aagaaaaatg
    43201 tttttggcaa tggcgaagga tataagggtt atacttataa aacttgctga tagattgcac
    43261 aacatgagaa cattaaaata catgcctcca gaaaaagcaa agtataaagc aaaagagaca
    43321 cttgaaattt atggtggtat agctcataga ttaggaattt ccaagataaa gtgggaacta
    43381 gaagacagag cattaagatt tatggaccca gaagggtatt atgatttagt tagtagagta
    43441 tcaatgaaga gaagtcaaag agaggattat attcaaggaa ttgttgaact tcttaaagat
    43501 aagtttaaag atttaagtat accatgtgat gtatatggta gaccaaagca tttttacagt
    43561 atatatagaa agatgcaaaa aaaacataag acttttgaag agatttttga tttaacagca
    43621 gtaaggatat tggttgataa tgtaaaggat tgctatgcag tacttggtat agttcataca
    43681 ttatggagac ctattccagg aagatttaaa gattatatag caatgccaaa acccaatatg
    43741 tatcaatcat tacacaccac tgttgtaggt cctgatggag aacctttaga gatacaaata
    43801 agaactcatg agatgcataa tatagctgaa aatggtatag cagcccattg gaaatataaa
    43861 gaaggtatct ctagcaaaga gtcaaaggtt gaagaaaaac ttcaatggtt gagacagatg
    43921 atggagtggg aaaaagattt aaaagaccca caagagttta tggatgcact taaagaagat
    43981 gtatttaata gtcaagttta tgtatttacg ccaaaaggag acgtaattga attaccagca
    44041 gaatcaacac ctatagattt tgcctataga gttcatacaa atgtaggtaa taaatgtgta
    44101 ggagctaaaa ttgatggaag aatagttcct attgattata agcttcaaaa tggtaatatt
    44161 gtcgaggtac ttacatcatc taattctaat ggaccaagta gggattggct taatatagtg
    44221 aagaccccaa atgcaaaaag tagaattaga caatttttca agaaggaaag aagagaagaa
    44281 aatgttgacc gtggaaatac aatattagaa agagaattta agaagcatga tataccacaa
    44341 aaagaccctc ttgttgaaaa atatatggca ttagttgcta agaaatttaa tcagccaagt
    44401 gttgaggact taattgccac tgtaggttat ggtggtataa tgtcatctca agtggtatct
    44461 aaggtaaaag acctatattt aaaagaggtt aaaaaagcta aaaaggaaca acagatacaa
    44521 gaagaagatt taaataaaca caatataagt gaaacagaat acagtaaaaa gagaaagaaa
    44581 aacgcatcac aaggaattat agtaaaaggg cttgacaata tcttagtaag atttgctaag
    44641 tgttgtaatc ctcttccagg agatgaaatt gtaggatata ttactaaggg taggggagta
    44701 gccatacaca gagctgattg cccaaatgca aacaataatg gtgatttctt ccaaaataga
    44761 ttggtggagg tttcatggag ttcagcagga aaaggtaagt ttgaagcgga aattcaaata
    44821 aaagctattg acagaagagg aattgttaat gaaataactc atattgttgc aatggataaa
    44881 cttagtttaa acggaataaa tgcaagaaaa ggtaaggata gtattgtaag tataaactta
    44941 cttgtagagg ttaatgacac agaggaatta aaaattctaa tgaaaaaatt aaaagcaatt
    45001 cctggtgtag aaagtattta tagaatgaca aattagagtt aaaataatag ggaggaaact
    45061 atgagagcag tagtgcaaag agtatcttca tctaaagtta cagtagatga aaacactata
    45121 ggtcaaataa ataaggggtt actagtattg ttaggagtga ctcatgatga taaatcaagt
    45181 gatgtagatt atatgattga taaaatattg aatctgagaa tttttgaaga tgaaaatgac
    45241 aagatgaatt tatctctaat ggatataggt ggagagcttt tagtagtatc tcaatttact
    45301 ttatatggag attgcagaaa aggaagaaga cctggattta gtaatgcagc tagaccagaa
    45361 cttgcaaata acctttatga agaatttgta aaaaaagcaa aagataaagg tgtgacagtt
    45421 ggtacaggtc aatttgcagc tcatatgatg gtagagttaa ctaatgatgg tccagtaaca
    45481 atactattag actcaagtaa atctttttaa gggggaaaac tttaatgatt ataaaaaaat
    45541 ttgtagatag ttattttgga gtaaatactt atgtattagg tgatgaaaag actaaaaaat
    45601 gtgcagttat agacccaggt ggaagtttag tagagacatt aagttttgta aaagaaaatg
    45661 aattaaatat tgaatatatt atccttactc atgggcatgg agaccatata ggatatgtta
    45721 aggatattaa agaaaaaact ggtgctaaag tagttgcaca tgttgatgaa aaagaattat
    45781 taaatgacaa aaataaaaat ctaagttata caatgagatg tggagcgcaa gagtttgatg
    45841 cagatatcta tgtaaatgat aaagacaagc ttgaacttgg tgaattaaaa atgactttct
    45901 tgcatactcc aggacatact caaggatgta tgtgtataag agttgaagat gaaatgttca
    45961 caggagatac tttgtttgct ggaagtattg gtagaactga tttatatagt ggagacttta
    46021 accaaatgga aaaatcactt aagaaattat gtaaatatga agatgctgtt agagtatatc
    46081 ctggacatgg accaaccagt actctagggg ttgaaaagaa gacaaatcct tacatgtaat
    46141 tttatattag tatttaaaaa agtataaaat atttaataac tatattagtg agggggttct
    46201 tctactgtta aatagaagga gttaagttga tgttgtatgt ttttttaaaa ggacatgatt
    46261 ataagtatga agtagcagaa cttataaaat tgtttactag tgaatttaag tttaaagact
    46321 ctaatgctaa caataatata gagtcaaagc atttaataaa tagattgatt tatgagaatg
    46381 gtgtattatt ctcaagtact gaatactatg aaaatggaaa cttaaagtac gagtcaatac
    46441 agaatataga aaatatgaat cttgaatttt tagatggatt tgatagcagc aaaacgattg
    46501 aagaatttct taatagccta gatagtgaaa gtaagaggaa ctttaaaaag ctgtgtaaag
    46561 aaaatatcaa aaaaagcatg tttttagtgc ttaaacaagt atttaattct tatgtaccat
    46621 ggggaatttt gactggtatt agaccagtca aaattgtcca caatttaatg gataaaaagc
    46681 tagatgataa tagcataaga accattctaa aagataatta ttttataata gatgagaaaa
    46741 tagatttagc tcttgaaata gctaaaagag agcgattatt tatgtatcct atagataaaa
    46801 ataaaatttc tctttatgta agtattccat tttgtccaac tagatgtgta tattgttcat
    46861 ttccttcaaa ttcattaaaa caatttggac atttaaaaag agaatatgtt tataaattga
    46921 ttgaagaaat taaggggttt gccaaagtta ttaaggatac taagaaagaa gttgaaactc
    46981 tatatattgg tggtggaact ccaactacac ttgatgagga agaattggat ttgcttataa
    47041 attcattgtt caatgaatta gatttaagta aaattaaaga atttactgta gaagcaggta
    47101 gacctgacac tattacagaa caaaaactaa gagtgttaaa aaaacacaat gttagtagaa
    47161 ttagtataaa tcctcaaact atgaatgatg ataccttggt aaagattgga agagagcata
    47221 gagtatctga tttagtagat tgctttaata tggctcgtag aatgggattt gataatataa
    47281 atatggatat aattttaggt cttatagatg aagacttaaa tatggtaaag aacacattgg
    47341 aggagataaa aaaactttct cctgaaagcc ttacagttca tacattagcc ataaagagag
    47401 catctaactt aaatataaat atggataggt ataaagaaca tctaacacaa tatgaagaaa
    47461 tggtaaaaat gatagattta tcaatgaaat atgcaaaaga tatgggatta aatccatatt
    47521 atatgtacag acaaaaacat atgttgggaa atttagaaaa tataggttat gctaaagaag
    47581 gatatgagtg catttataat atacagatta tggaagaaaa acaaagtaac tatgcattag
    47641 gtgcaggtgc tatatcgaaa tttgtctatg tagatgaaga tagaattgaa agagtagaaa
    47701 atgtaaaaaa tgttgaacaa tacattgaaa gagtagatga aatgataaaa aggaagaaag
    47761 aagaggtata taaaaatgtt gactaaagct cctagaggaa ctaaagacat aactccaaaa
    47821 gaggcttaca aatggcgtta tgtagaaaat aaatttagag aaatatgtgc tttatatgga
    47881 tatgaagaaa tggtaacacc tatatttgaa catacagaac ttttcaagag aagtgttgga
    47941 gatactacag atatagttca aaaagaaatg tattctttta aagataaagg tgatagagaa
    48001 attaccctaa agccagaagg tacagcaggt gtagtaagag catttataga aaataaatta
    48061 tatgcagata ctcaaccaac aaaattattt tatgtgacac cttgttttag atatgaaaga
    48121 ccacaagctg gtagacaaag acaatttcac caatttggaa tagaagcact tggaagtgat
    48181 actccttcaa tggatgctga aataatcgca ctagctgttc aattttttaa tgaagttgga
    48241 ttaaatgatt tggtagtgag tataaattca gttggctgtc cagtttgtag aaaagagtac
    48301 aatgctttat taaaagagta tcttgactca aaagctgata tattgtgtga tacttgcaat
    48361 gagagaagag aaaaaaatcc aatgagggtt atagactgta aaaatcctac atgtaaagaa
    48421 aatatcaaag atataccatt tattgcagac catttgtgtg atgattgtaa atctcacttt
    48481 gataaacttc aagaatactt aaaggaaatg aatataaact ttgtaattga taaaacaata
    48541 gttagaggct tagattacta tagaaaaact gcttttgaaa ttatatctaa tgatatagga
    48601 gctcaaagta ctgtatgtgg tggaggaaga tatgatggtc ttgttgaaca attaggagga
    48661 ccaaaaggta taagtggaat tgggtttgga ctaggaattg aaagactttt acttacactt
    48721 gaaggtaatg gaattgaaat agaaaaccct caatctacgg atatatttat agtaactata
    48781 ggtgaagaag caaatacaag aagctttaaa ttgttaaaag acttgagaca aaatcatata
    48841 agtgcagata aagaccatat agagagaagt gttaaagcac aatttaaata ttcagataaa
    48901 ataaattcaa aatttacaat agtaattgga gatgatgagc ttaaaaatga cactgcgaca
    48961 ttaaaaaata tgaaaacatc agagcaaact actgtaaaat taagtacatt agttgaagaa
    49021 ttaaagcaaa agctgtaaaa taagaaagta tgatgttttg tgtattagat aaatatatag
    49081 cattaaaatt aaataaaatg gaggtagtat cttggaaact ttaaagggtt taaagagaac
    49141 tcactactgt ggagagttga gagaaaaaaa cataaatgaa gaagtcgtac ttatgggatg
    49201 ggtacagaaa aaaagaaatt taggtggtct tgtatttgtt gatttaagag atacaagtgg
    49261 attatgtcaa atagtttttg atacagatgt agataaagaa gcttttgaaa aagctgaaaa
    49321 attaggggct gaatttgtaa tagctgtaaa aggaaaagta tgcgaaagac aatctaaaaa
    49381 ccctaatatg ctaactggtg atatagaaat atttgcaact gaacttagac ttttaaacaa
    49441 gtcagaaact ccgcctattt atataaaaga tgatgatgat gtttctgaag cactaagatt
    49501 aaaatataga tacttagatt taagaaaacc atctatgcaa agaaatttaa aattaagaca
    49561 taaagtaatg aatattacaa gaaattactt atcaaacaat agattttgcg aaatagaaac
    49621 accattttta atagctccaa caccagaagg agcaagagat tatctagtac caagtagagt
    49681 taatccagga aaattttacg cattaccaca atcaccacaa ttatataaac aattattgat
    49741 ggtaagtggt atggatagat atttccaaat agttaaatgc tttagagatg aagacttaag
    49801 agcagataga caaccagagt ttacacaaat agactgcgaa atgtcttttg ttgagcaaga
    49861 agatgttatg agtatgattg aaggtttgct tgaagcgata tttaaagaag ttttagatgt
    49921 agaattggca cttccacttc ctaagatgac ttatgcagaa gctatgtcta aatatggttc
    49981 agataaacca gatactagat ttggatatga gttaacagat atatctgatg ttgtttgtaa
    50041 ctgtggattt aaagtgtttg ctgatgctac acaaccagga aaaagtgtta gaggtataaa
    50101 cgtaaaaggc aaagctgacg actttactag aaaacaaata tcatcactag aagaacatgc
    50161 taagacatat agagcaaaag gtcttgcttg gatgaaagta ggacaagaag gagtaacttc
    50221 tccaatagca aaattcttta atgaagaaga aatgaacgct atacttacaa gaatgaatgc
    50281 tgaagtagga gatttacttt tatttgtagc tgataaaaac tcaatagtat ttgatgcttt
    50341 aggacaagtt agacttgaag tagcaaatag gcttaatcta ttggataaaa atgtatataa
    50401 cttactatgg gtaactgagt tcccagtttt tgaagaagat gaagaaacag gcacattctc
    50461 agcaatgcat cacccattta catcacctat ggatgaagat ttagacaagt tagaagaagg
    50521 tgataagtca tctttaagag cgaaagctta tgatattgta ttgaatggtt atgaaatagg
    50581 tggaggaagt gttagaatat caaattctga tgttcaatca agaatgttta aagcacttgg
    50641 ttttacagag gaaagagcta atgaaaagtt tggttattta ttagaagcat ttaaatatgg
    50701 tactcctcct catgctggtc tagcttttgg tcttgataga cttgttatgt tacttgcagg
    50761 aactgataat ataagagaag ttattgcatt ccctaaaaat caaaatgctg tttgccctat
    50821 gacaaatgct cctacattgg cggaagatga gcaattagaa gaattaagta taaaagttga
    50881 tataaaagat aatgaataat atgtagttgc aagaaactaa aatgtaaaaa gtctggatat
    50941 aaaatatatt tatattcaga ctttttttat tagaattatt ttatattttt tctctatata
    51001 ttttcataaa ttatacttat attcttaacc aatataatta aaatactatg tttaaaaatt
    51061 ttacataaac ttgattattt tagaaactac ttctgtaatg agtacacgat tttaattaaa
    51121 gaatatataa caaatttgaa ataagtctaa tatatgactt aatagattaa attaaaataa
    51181 taaatttgga ctatttatct atttataact t
//
LOCUS       DAEPKC010000018        48367 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.018, whole genome shotgun sequence.
ACCESSION   DAEPKC010000018 DAEPKC010000000
VERSION     DAEPKC010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 48367)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48367)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48367
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.018"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(143..619)
                     /locus_tag="KR294_001143"
     CDS             complement(143..619)
                     /locus_tag="KR294_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239231.1"
                     /translation="MVKKRLVAVVISLAMISVGNFSYAHSGGHNSSGDHHNKNKSELT
                     RYYCGGHSAHQHNKGFCPYASTKENSGVTISSVHNEKNHKNYFAEKGYNKGYEDGCKG
                     LYNLSVTEAKSDNLYEKEILKSSYEKGYLIGYNEYKAKKVDDVMKKMLDIPMLASI"
     gene            complement(818..2443)
                     /locus_tag="KR294_001144"
     CDS             complement(818..2443)
                     /locus_tag="KR294_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH0239232.1"
                     /translation="MLQVTGVGLRFGDKELFKDVNLKFTKGNCYGIIGANGAGKSTFL
                     KILSGEIEPNTGSISITDKERMSVLKQDHFEYEEETVLNVVIRGHERLWNIMKEKDAL
                     YMKEDFNEEDGIKAAELEGEFAELDGWDAETNAEKILMGLGITKDMHYKQMKELVGGE
                     KVKVLLAQSLFGKPEILLMDEPTNHLDFKSINWLNNFIMDLEESIVIIVSHDRHFLNQ
                     ICTNIVDVDFGKIQMYVGNYDFWYESSQLALQLAKDQNKKTEEKIAQLKEFIARFSSN
                     ASKAKQATSRKKQLEKLEVEDIQPSRRRYPYVGFTPAREIGNEVLEVHNLTKTIDGVK
                     VLDNVSFRLDRDDKVVFMGDEIATTALFNIVMGELEPDSGEYKWGVTTSQDYLPKNHN
                     KFFDGVEYSLVDWLRQFSEEKSESFIRGFLGRMLFSGEEALKEAQVISGGEKVRCMLS
                     KLMLSNANVLVLDDPTNHLDLESITSVNKGLEKFPGVLLFTSHDHEFISTIANRIIEI
                     TPNGIMDRKMDFDEYLESKEIQDQLAKMYGKDK"
     gene            complement(2781..3800)
                     /locus_tag="KR294_001145"
     CDS             complement(2781..3800)
                     /locus_tag="KR294_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-binding protein"
                     /protein_id="HBH0239233.1"
                     /translation="MKLIKTIDAVGQVLCHDITQIIPGEFKGRKFKKGHIVKEEDIPV
                     LLSLGKDNLYVWEKSEGMVHENEGALFLKELTAGENLDFSEIKEGKIDFIAACDGLLK
                     IDVDALFDLNCVGEIMMATLHNNFIVNKGLKVAGTRVIPLVIDEKKLEDAKKVVGNRK
                     IVNVVPFKPKKVGIVTTGNEVFYSRIVDKFGPVIEEKVKGFGCEVIGQTICPDDKEII
                     KSAIKEFISQGAELICCTGGMSVDPDDVTPTAIKETGADLVTYGSPILPGAMFLLAYY
                     GEVPIMGIPGCAMYHKTTVFDIVLSRVLIDEKLDKYDIARYGHGGLCMNCDVCTYPAC
                     NFAKI"
     gene            complement(3797..4366)
                     /gene="mocA"
                     /locus_tag="KR294_001146"
     CDS             complement(3797..4366)
                     /gene="mocA"
                     /locus_tag="KR294_001146"
                     /EC_number="2.7.7.76"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor cytidylyltransferase"
                     /protein_id="HBH0239234.1"
                     /translation="MINAVIMASGFARRMGANKLLLNYKGCSIIEHVFREVSKIDFHQ
                     VVVVSQYEEVLLLCNKYGFEYIDNKNANIGQSESIKLGVLNSSKCDGYMFFVGDQPFI
                     DNLYIDKIINTFKLDRDFIVIPRYKDMCGNPVIFPYSKKEELLALKEDEKGKTILKNS
                     SKIKYVEVPKEMLFDIDTKMDYERIGGKL"
     gene            complement(4473..5195)
                     /gene="yqeC"
                     /locus_tag="KR294_001147"
     CDS             complement(4473..5195)
                     /gene="yqeC"
                     /locus_tag="KR294_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative selenium-dependent hydroxylase
                     accessory protein YqeC"
                     /protein_id="HBH0239235.1"
                     /translation="MELSNIIEKNEIITVVGAGGKTSFINYFANFYRDKLKVLLTTTT
                     KIYVPNDYDNIIITIDGTVIPSICHGITVCGSYINNENKLVSIDSSILDEIVDQFDLV
                     LIEGDGSKRKKLKGWNAKEPVVYHKTTKTIGILDITSFGMNINEENIHRVEIFKKIAN
                     LDTSSINSSSTVSIENLKNIVLNPNGLFKNYSGKRVLFINKVENEKYKNLAIKLVENI
                     KEYESEIEIFYGSVKQKFCVRY"
     gene            complement(5378..6655)
                     /locus_tag="KR294_001148"
     CDS             complement(5378..6655)
                     /locus_tag="KR294_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBH0239236.1"
                     /translation="MSNRIKNIHYGTQRQQLKNLTKKEYQALREMCFLAKNLYNVGTY
                     NVRQHYFNQGEHLNYEANYHVCKENENYKLLNSNIAQQILKEVDSSFRSFFGLIKLAK
                     EGKYDFRGIKSPKYLDKEGFFSIIIGQIRIKEDGILNVPMSPAFKKLYGKVSIKVPQN
                     ILEKKIKEIRIIPKHKARFFEIQYCYEIPKSEEVSNQKNALAIDLGLENLCTCVTNLG
                     DSFIIDGKRLKSVNQWANKQNDKIEALKLKKNITAITRKQFKVWNKRNNQVKDYVNKT
                     CFYIIDYCVKNNIGNLIVGYNAKLEKSDNMERKIYRNFIRIPFGEIKGKLEYLCKIKN
                     INFIRQEESYTSKSDFFADDFLPDINVDNVKKYDFKGERITRGQYKSSVGIIINADVN
                     ASLNILKKSQVVNLSNLQNNPQILKQPQRVRIS"
     gene            complement(6794..9100)
                     /locus_tag="KR294_001149"
     CDS             complement(6794..9100)
                     /locus_tag="KR294_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HBH0239237.1"
                     /translation="MINKGIRKIDSTAIVTGKPLYTEDLIMHKDVLTLKLLRSPHAHA
                     KIKNIDTSKAEKIPGVVGIYTYKDVPQVRYCVPGQTEPEASPYDRVLLEDTVRFIGDE
                     VALVAAEDEKTALKALKMIKVDYEVLKPVFDAREAEGNEVVIHPEKDIVEPYPFGLDA
                     KNNIVSKEFFEFGDVEAKLKESDFVVESSYKTQSQSHCMMETHRSYSYKDINDRIVVV
                     SSLQSPHNVKRILRKVLGIPSSKIRVIKPRIGGGFGGKNIAATDIFTAFVTMKTGRPA
                     KFVFTRSETFVGSNSRHEMFFDVKVGADKEGNLKAIELKSLNNTGAYGGNGVSVSSES
                     GHNTLPIYNDIDAVRFNARTVYTNRLPAGALRGYGATQGIFAIDSAIDELAHKIGMDP
                     LEFRIKNIIDRYTNGKAAEDEILSCELRQCIEKGKKLINWDDKYPCKDIGNNKVRAVG
                     MAVANHGSGIPRVDMATVTIRMDEDGTYKLLSGLADLGQGADTIQAQIAAEALNTTVD
                     RISIYTGDSDLCPYDTGAFASCTTTVTGNATIKTANKLKDILLSVAESKLGFKKEDLE
                     LGKDRVFVKNDNSKFVLLEELGRESVGGIGFASDDVPVVLEATESFGMLKKIKPFIAG
                     FAEIELDKNTGEYKVINFACVPDCGTVINPTLARIQVEGGVMMGIGFAMYEDPIFDKD
                     GRLLTDSFLQYKVPTKKEVGNILVDFAENFDPGGPYGAKSLGEIVIHTPAPAIANAIF
                     NATGVRLRELPMTFEKVYMGMKNNNKQL"
     gene            complement(9093..9887)
                     /locus_tag="KR294_001150"
     CDS             complement(9093..9887)
                     /locus_tag="KR294_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD binding domain-containing protein"
                     /protein_id="HBH0239238.1"
                     /translation="MVTIKEYSVPQSLEEAYKILISKKNNVILGGCGFIKLSNKNIGT
                     AIDLKDINLNYIKEDKKNILIGADTSLRSLEIDKTIKNYCSGILSSAVSNIVGVQFRQ
                     GARIGASVFSKYGFSDLIPALLVVGAKVRLYNKGILELSEFLDSELSRDILVEVILPK
                     KDAIAVFDSIRKCTGDFSVLNSAMLKENDTYKIAIGARPQKARLALEASNILNKEKDI
                     DKASIVASKELTYGSNMRASKEYRKDMASALVKRMYNAIEEGMYND"
     gene            complement(9994..11352)
                     /locus_tag="KR294_001151"
     CDS             complement(9994..11352)
                     /locus_tag="KR294_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine/pyrimidine permease"
                     /protein_id="HBH0239239.1"
                     /translation="MKAKSTSKFELDGIPPLKEAIPLGLQHLMAMVIGSCLPAILIAN
                     AAGLNHKMSTLLIQAALVFAGLSTLLQLYPIPLFKGFKLGGGIPVIMGATAMFIGAGV
                     SVASKYGLPVLFGSQIIAGIVIIIIGFGLKKIRFIFTPAVSGTIVACMGLGLFPIAIK
                     NLAGGMGNETFGNPINFIVGISVSLMILGLNKYGKGLFKDASILVSIIFGYILSLILG
                     IVNFSSIQEFTLVALPKPLAFGLDIRLEVVVMFSIIYLVEIADIMGACTLSAVGGLNR
                     QVTDEELSSAVLGNGVLSTIGALFSATPMGMFGQNSAIVSNTKVVSKFVLAIGGIGLF
                     LAGISPLLANLIRTIPPCVVGGATLVIFSTLTTSGLRLVSMDGFNQENSMILGLSMAS
                     GIGFMVAPQVLEKFPKFIETLLADSSVVSGAMVAIIIQALYMVKFPGNKSDKVEDKNK
                     SL"
     gene            complement(12700..13707)
                     /locus_tag="KR294_001152"
     CDS             complement(12700..13707)
                     /locus_tag="KR294_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239240.1"
                     /translation="MVMQVQEKILELLYTINEDVVSIKNDMSEVKQEINVLKEDMSEV
                     KQEMTVMKEDMSEVKQEINVLKGDMSEVKQEMTVMKEDMSEVKQEITVMKEDMSEVKQ
                     EINVLKVDMSEVKQEMTVMKEDMSEVRQEINIMKEDMSEVRQEINTMKEDMSEVRQEM
                     TVMKEDMSEVRQEMTVMKEDTSEVKQEINVMKKDMSEVRQEITVMKEDVSEVKSEVNF
                     MQNKINNINEDMNGIKDEVSIANEKLYGIEIKIDSLECEDKSMKEIQIEQNNILGSLL
                     HNSEINKATHDNIEHNIAYIKGDTNSIKEDIAEIRRDLNLVELATSKNWSDIVKLKSV
                     K"
     gene            complement(13937..15022)
                     /locus_tag="KR294_001153"
     CDS             complement(13937..15022)
                     /locus_tag="KR294_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HBH0239241.1"
                     /translation="MYNFLGKELKSPLIIGSGPLTYSAAGCKILSDAGAGAVVTKTIR
                     KERAINPAPHMVRNTANALLNNEKWTDFEPEQWIDFEIPQMKRDGTVCIASVGHTIEE
                     SSELVEKVANAGADFIELVSYDYRDLIPMLKDAKERVNIPVIVKLPPMIDEIGDFAKK
                     LEEAGADAITACDSVGPAFRIDIETGQPLLGGNGIGYLSGETIKPITLQRIYEIKKQV
                     NIPIIGLGGCVSGDDALEMIMAGADFVGICSVVILKGAQVISKIHDDLKSNLNRLGYN
                     TIENACGIVHNHMGDVNERLSFEFTYDEEKCTKCKMCERVCAYQARKLNDKMELNEEE
                     CRYCGLCISVCKPKALGRKISCSELNV"
     gene            complement(15058..16371)
                     /locus_tag="KR294_001154"
     CDS             complement(15058..16371)
                     /locus_tag="KR294_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HBH0239242.1"
                     /translation="MIAIKSKYLISSADEIYTNSAVVVENDIIKDILPNEEVEIKYKN
                     IEEIIDKSDAIIMPGFVNGHMHQYGVLSRGIPANVHFTDFEGFLNDYWWPFIENRIGL
                     KEVKATTKASAIELIESGVVAFCDTLEAPNTEEGTLIEQGKILEEIGMKAILSLESCE
                     RISFENGLRCLNENSNLIKWSRENSKLINGIMCTHTSFTCSDRFIKKAKEDTKKLNAP
                     MQFHLCESIYEPNYAEKHFGKKAVDYYNDLDILDETVLASQCVKVNDEEIDILKEKGV
                     KVVHMPLSNCEVGGGFSPVPKMIKKGIKVALGTDGYINDFFEVMRGAFLMHKSVEEDA
                     SVMPANLVFRMATEHGAYVLGLQNSGKIAVGNKADIIVMEDEFKTPVTLDNIFDQIVV
                     QGKKEFISNVYIDGRHILKEKQLVDLDKKAIVKEMKEVACEFWKF"
     gene            complement(16372..18663)
                     /locus_tag="KR294_001155"
     CDS             complement(16372..18663)
                     /locus_tag="KR294_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HBH0239243.1"
                     /translation="MVNKEVRKIDSEAIVTGKPIYTEDLIFHKDVLTIKLLRSPHAFA
                     KIKNIDIKNALKVKGVVNIFTYKDVPNYRYSMVGESYPEASPHDQLILEDVVRYVGDE
                     VAIIAAEDERAAIKAMKLIKVEYEVMTPILDARESEGNKILIHEEDDLFCPFDFGLDA
                     TKNIVSREKMGKGDVEKEFKESDVIVEHSYMTQSQAHCMMETHRAYTYIDTNGRLVVT
                     SANQSAYHMRRQVSKALGIPLSKVRVIKPRIGGGFGGKNIAVTEIYASFVTWMTKRPA
                     KLIYTREETFAMTNTRHQMFFDIKIGSDKEGNIKAIDMKALNNTGAYGDNGPSVCSES
                     GHNVLPTYNNVPAIKFDGRTVYTNLVPGGALRGYGATQGTFALDCAIDELAHKLNMDP
                     TEIKLKNIIKKQTEGGIMNFPIRSCALDECIIRGKKLIGWDEKYPVRDIGNNKVRAVG
                     MSVGTHGSGIANIDMAIVNMRMDEDGTYKLFSGSSDLGTGSDTILAQIAAKALNTSID
                     RISVYTGDTDMCPYDTGAYASCTTYVTGNATIKSAESLKQKILKVAQKKLDLPIDDLI
                     LYEDRVCYSEDVEKFVLLSELGKESVGGGNQEVLYSSESYGIQESAKPFLAGFAEIEL
                     DKTTGEFKVINYACSTDCGTVMNPALARIQVEGGVTQGIGLAMYEDPRHGSDGKLQTS
                     NLLQYKVPTKKDIGNIIVDFVDNYEPTGPYGAKSLGEIVIHTPAPAIANAIYNATGVR
                     IRELPITSEKVYMAMKKLNQGGK"
     gene            complement(18653..19447)
                     /locus_tag="KR294_001156"
     CDS             complement(18653..19447)
                     /locus_tag="KR294_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD binding domain-containing protein"
                     /protein_id="HBH0239244.1"
                     /translation="MITIKEYVVPKSLDEAYELLISRKNNIILGGCGFLKLGSKNIGS
                     AIDLKDLALDYINETDDSILIGADTSLRTLELNKVIKNYCNGVISNAVSNIVGVQFRS
                     GARVGASVFAKYGFSDLIPSLLVVDAKVKLYKKGVMNLADFLENELEKDILIEVILPK
                     KDAIGVFDSIRKCTGDFAVLNGAMLKEGSIYKIAIGARPRRAKIAYKASEILSLENDI
                     EKAGEVSSEELSFGSNIRGSKEYRKDMAKALVVRMYNSIGGECDGK"
     gene            complement(19486..19932)
                     /locus_tag="KR294_001157"
     CDS             complement(19486..19932)
                     /locus_tag="KR294_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2Fe-2S iron-sulfur cluster binding
                     domain-containing protein"
                     /protein_id="HBH0239245.1"
                     /translation="MIIKCTINNKEKELSIRPDDFLADTLRENGYVSVKKGCDTGSCG
                     LCTVMVNDKAVLSCNYLTARVEGQHITTLEGVLDEAKKFGDFLADEGADQCGFCAPGF
                     IMMVLAMKRELQNPTEEEVIDYVNGNLCRCTGYKGQLRAIHKYLNT"
     gene            complement(20004..21410)
                     /locus_tag="KR294_001158"
     CDS             complement(20004..21410)
                     /locus_tag="KR294_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH0239246.1"
                     /translation="MMDILIKNAIIVTVNKEREVIFDGALVVKDNKIADIGNSKEIES
                     KYTDVKKIIDAKGKVLFPGFINTHNHLFQTLLKGLGDDMVLKDWLETMTFPAANYLEP
                     KDTYDAAMLGCIEGLRSGITTMVDYMYPHSKPGLCDGIIDAYKELGIRGILGRGCMNT
                     GAQFGVHPGIMQDVETVEKDVRRLFEKHHNTENGRIKIGVAPAAIWSNSQEMLEMLWR
                     VVKEYDDALFTVHISETPFDREAAKELHGQYDIDVLEKLGILGPNVLMVHCVYLTEKD
                     MELTKKYDMKVSHNTASNMYLSSGVAPVPEMLKKGITVSLGVDGAASNNSQDMLELMK
                     LTALQHKVNKCDPLAMSAEKVLELATIDGARAIGMEDEIGSLEIGKKADLLIFNPMLS
                     PKAIPMHNPVSTLVYSSSMKNIESVIVDGNIIMEDSKILTANEEKALKDAQDTAERLC
                     VRGTIKNRMEGHKWNSLY"
     gene            complement(21428..22798)
                     /gene="hydA"
                     /locus_tag="KR294_001159"
     CDS             complement(21428..22798)
                     /gene="hydA"
                     /locus_tag="KR294_001159"
                     /EC_number="3.5.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropyrimidinase"
                     /protein_id="HBH0239247.1"
                     /translation="MGTILRGGTIITSDKTYISDLRIEDEEIVEIGNNLEINGDKVID
                     ATGKIVIPGGIDTHTHFDMNAGSITTADNFETGTRAAIAGGTTTILDFAEANEGENLL
                     QGVEAYHKKASGNCYCDYGFHMTITCLNKDTFNHMEKLISDGIVSFKMYMAYDGMKVD
                     DGTIYRVLKKARDLGCIVGFHCENGDLLDVLIEENIQNGNLEPKYHPLTRPNIVEKES
                     VSRLADITKLSNSKSYVVHLSCRESLETVKMAREKNIDMIVETCPQYLLLEDNLYNKD
                     KFEGAKYVMSPPLRKKEDINYLWEGLSSGDIQTVGTDHCSFNFKGQKDLGIDDFSKIP
                     NGAPGVEHRLALLYTYGVLENRISANKFVEVTSTNAAKIFGMYPKKGEIAVGSDADIV
                     ILNINKEETISYKTQKQNVDYTPYEGFKVKCKVEDVFLRGNHVVQSCNVKEHPTGQYI
                     KRKITK"
     gene            complement(22931..24118)
                     /locus_tag="KR294_001160"
     CDS             complement(22931..24118)
                     /locus_tag="KR294_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgeY family selenium metabolism-linked
                     hydrolase"
                     /protein_id="HBH0239248.1"
                     /translation="MLNEQRKQEVTEICQKLIQNPSSSGNEEGVVKAIEESFEKLGFD
                     SWSRDRYGNIVGCIKGNKPGKKILFDGHIDTVPVPDASKWSVPPFEGKIVDGKIYGRG
                     TSDMKGQYTAMMSAVAYFAKDTNRDFAGELYVAGVVHEEIFEGVSAREISKAVQPDYV
                     VIGESSELNLKIGQRGRGEIVVETFGKPAHSANPEKGVNAVYKMANVIQKIQQLVPPT
                     HPVLGDGILVLTDIKSSPYPGASVVPDYCKATFDRRLLVGETREGVLAPIQALLDEMM
                     KEDPELNAKVSYAVEKADCYTGNTIESERFFPGWLYDEEDEFVQAAYKGLKEAGIDSE
                     ITQYSFCTNGSHYAGEAGIKTIGFGPSKENLAHTIDEYIEQEQLFIGTEGYYGILKSV
                     YGK"
     gene            complement(24245..25459)
                     /gene="dpaL"
                     /locus_tag="KR294_001161"
     CDS             complement(24245..25459)
                     /gene="dpaL"
                     /locus_tag="KR294_001161"
                     /EC_number="4.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopropionate ammonia-lyase"
                     /protein_id="HBH0239249.1"
                     /translation="MLKEIKWKVNNLPKGDKENCIKFLNEEEITKVRNFHKSFPQYKE
                     TPLANLEGLAKKLGVAGVYVKDESYRFGLNAFKVLGGSYSMGRYLAQRLDTDISELGY
                     DKLTSKEIKEKLGEITFFTATDGNHGRGVAWTANKLGQKSVVLMPKGSSEFRLNKIKG
                     EGADASITDLNYDDAVRLANDYAEADDHGVMVQDTAWDGYEEIPAWIMQGYGTMAQEA
                     IEQLKEYGVDRPTHVFVQAGVGSLAGAVQGYVASIYDECPITVVVEADEADCYYKSAE
                     AGDGKPRFVGGDMPTIMAGLACGEPNTIGFEVLKNHAAAFVSAPDWVSAKGMRTLGNP
                     LNGDEKVISGESGAVTTGLLVAAMEREDLADLRKDLKLDENSRILLISTEGDTDPDKY
                     RSIVWDGEYPSI"
     gene            complement(25822..26493)
                     /locus_tag="KR294_001162"
     CDS             complement(25822..26493)
                     /locus_tag="KR294_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBH0239250.1"
                     /translation="MAKILGICGSPRKGATEYAVLEALKEAETIPGIETEYWSVRGKK
                     ISPCVHCDACIRKETMCIIKDDIQELEQKILEADGIIVGSPVYDMNITAQLTAVFNRL
                     RPMYLVHPGKLQNKVGAAITTGGTRYGGQELTKLPIINFFLMHEMLVSGGLGGCYIGG
                     TIWSKDGKAKGAQEDETGMDTVKRLGKGAAEAVMVSKFGLEKWNVVKEELDVKKDEKS
                     PLRDH"
     gene            complement(26576..28792)
                     /locus_tag="KR294_001163"
     CDS             complement(26576..28792)
                     /locus_tag="KR294_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HBH0239251.1"
                     /translation="MEKVIGKSYPLKDAALKVTGQMKYVADMKPQNVLYAKMLLSPVA
                     HAKIKSIDTSEAEKVVGVRAIATYLNTSQRKYNGSLRFYEHKIPENEVIFSDTVRFVG
                     DRVAAVAAETPEIAEKAVKLIKVEYEELPAVFTIQDAIKEDAICIHGDSNIVSQNNIN
                     GGDVEKGFKECDYIFEDEYSTPAIHHSAIETHSVIAHYDYNDKLTVHTPCQNTFGFRI
                     ILSQIFGMSLNKVRVIRPAIGGSFGGKLELTIEPVAAALSKMTRRPVKMVLTRKESMI
                     STRTRHGSFVKLKTGVNKDGEVIAQDIKIYTNTGAYASSALNVIGALSHKVFKVYKIP
                     NIKFTGMPVYTNTPIAGAMRGYGSPQIFMAQQAQFAKIAKEIGMDLVDFQNKNAVEPD
                     DVDIIFHGSLGNPRVLDCIEQGKKMFKWDEKKKLPKEEGKYLRGIGMAIGAHGNGVFG
                     AHRDVVTLTLKLNEDGTLTLLTGAHDMGNGVVTMQTMMVAEVLGITPDKVDTFETDTD
                     ACTFNLGDYASRGVFVEGGGAKKTAEKLKNLILEEAEKLLETSKEDLYLDNGCVISKL
                     DENVKASLSDVAVYSQSKSLRELTVVEDYSSPAGRTSYGVHFAEVLVDKETKDIKVVD
                     FVAVHDVGRVINPLNLEGQLEGGIHMGLGYALSEELAFDEQGRPKATDFKTYKLFRTV
                     DMPKCQVAFVDGYEKAGPFGGKSIGECAVVPVAPAVANAVYNATDVEIHSLPIKLK"
     gene            complement(28795..29265)
                     /locus_tag="KR294_001164"
     CDS             complement(28795..29265)
                     /locus_tag="KR294_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(2Fe-2S)-binding protein"
                     /protein_id="HBH0239252.1"
                     /translation="MEKIKLNINDYMYEIEVEKNETLLHVLREKLNLTGAKQGCNSGS
                     CGACKVLIDGVDMKSCKLLAKNCEGKVIYTIESFANGENLHPIQEAFIEVGAVQCGYC
                     TPGMIITTQALLNRNASPNEDEIREAFKENLCRCTGYVKIIEAVKLSAARLGGR"
     gene            complement(29327..30721)
                     /locus_tag="KR294_001165"
     CDS             complement(29327..30721)
                     /locus_tag="KR294_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH0239253.1"
                     /translation="MIDILIKNAIIVTVNKDRDVIFDGAIAIQGDRILDIGNTVDIEP
                     KYLDAKKVIDANGKVIFPGFINTHNHLFQVLLKGLGDDMALHEWLNTMMFPSAKFLTE
                     QDTYDAAMLGCMEGLKSGITTMVDYMHTHNRPGLTDGIVKAYKDLGIRGVVGRGCIDL
                     GIHKELIEDVETVEKDLRRVFEKYHNSENGRIKICVAPSSMWAISEEMGKMLWNIVKE
                     YDSYFTVHISETEFARTATKDIHGEIDIKLLEKWGIVGPEVVAVHCVCITDEDMEMLK
                     KYDIKVSHNVASNMYLASGVAPVPEMLKKGINVSLGLDGAASNNAQDMVELMKLTALQ
                     HKVNNCDPLAISAEKVLEMATIEGARTLRMEDEIGSLEIGKKADLVIFNSMLSPKSIP
                     LHNPVSTLVYSASMHNVESVLVDGNVILENGKVTTIESEEQVLLNAQHAAEELCKRAN
                     VTNRMEGHKWNSLY"
     gene            complement(30794..32155)
                     /locus_tag="KR294_001166"
     CDS             complement(30794..32155)
                     /locus_tag="KR294_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine/pyrimidine permease"
                     /protein_id="HBH0239254.1"
                     /translation="MKTRNTSKYDVDGIPPLKESIPLALQHLLAMIVGNMVPAILIAN
                     VVGLNQGQATMLIQGSMLAAGLATFLQLYPIPLFKGFKLGSRLPVMMGMSYVFLGACL
                     SVAAKDGLAALFGAQIAAGVIVFFVGFGVKKIRHIFTPIVSGTIIACMGLGLFATAIK
                     NLAGGEGTQTFGSPINFTVGVIVAFVIIMINKYGKGLVKNSSILIGILVGYAISLVLG
                     LVDFSAVQGAAIVSLPTPAAFGLEFRPELIVMFTIIYIIGIADMMGACTIATVGAMDR
                     EVTDEELASVVLGNSITSIISSLFAALPTGVFSQNTAIVSMNKVTSRFVIALGALVLL
                     LAGISPALGAIMTTIPSCVVGGATLVVFSSIAMSGFSIMSMDGFTEENNLIAGVSIAT
                     SMGLTTAPQVLDQFPETIGTVLGGSSIVSGAIIAILLQTLFKLKSRKSAENVTSNLEE
                     NIG"
     gene            complement(32452..33774)
                     /locus_tag="KR294_001167"
     CDS             complement(32452..33774)
                     /locus_tag="KR294_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HBH0239255.1"
                     /translation="MFDIDGRPPILKCLPLSMQHILAMIVGTVTVPIVVGGAVGVSPT
                     QITLLVQYALIIAGISTLIQLYPIGNIGSRLPIIFGVGFTYVPTLVAVGGNYGLASIL
                     GAQLIGGVATVLIGIFIKKIRKFFPNIVAGTVVFTIGLSLYPIAINYMAGGVNSPTYA
                     SMQNWAVAAITLVVVIGLSQFAKGYAKLAAIFLGIIVGYCVSLVLGIINFDPIREATW
                     FAIPKPLEFGMEFDMPVIISVVIVSIINAVQAIGDLSATTMGGMDRNITDKELSSGVI
                     GSGICTMIGALFGGLPPSSYSQNVGMVAMNKVISRFVLGIAGIFMLLSGFVPKFGALM
                     TTIPYSVLGGATISIFSIITMTGIKLIITEELSSRNITIVGLAIALGMGITSVPAAQE
                     AFPSFVKLVFGESPIVIATLVAFVLNLIIPNKSLEDEAKERAVMEETN"
     gene            complement(34130..35170)
                     /locus_tag="KR294_001168"
     CDS             complement(34130..35170)
                     /locus_tag="KR294_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH0239256.1"
                     /translation="MDKHSDSVMYGGMEVYNIWGTTTVDSIIGESDVMRALKNRICKI
                     GNSDSTVAITGESGTGKELIARAIHLAGNRGNKTFVAINCAAIPEPLLESELFGYTKG
                     AFSGADSKGKIGKFELANGGVVFLDEIGDMPIQLQSKLLRVLQEKKFTRIGSNELIDI
                     DVRIISATNRDLFELVKENKFREDLYYRLNVIPLEVPPLRERGDDIQILINNFIDKYS
                     RKMKKNVYHIEPDVEQMLLKYPWPGNIRELENTIELALNLLEEDGIIHKGIINRKILE
                     YFKLNNINIKLLEESDYEISMEQDILTLEEFERAYIKKVLKFYGNDTKSKKLAAKKLG
                     ISLATLYRKIDV"
     gene            complement(35497..36765)
                     /locus_tag="KR294_001169"
     CDS             complement(35497..36765)
                     /locus_tag="KR294_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HBH0239257.1"
                     /translation="MSKNIYVKETYEWIRVGNGENELTEIEYEKLLKYLENNNDVLKS
                     NIIDIKYKKLRFINYVGIICFENVILEILPKLSLSDNLVKDREILLQMLSICNKIPIT
                     MNEKIRLSLKNYNLLNFFVMYFIESMQTQMKKGIYFEYINKIENLNVMRGKILLSTYA
                     KEKGISPMKIRCEYDEYSENNFLNQVLKKACISILCRINDNSIQGKIKKILSYFQNVD
                     LIYIDRKKLLDYKFYKNNDRFKDCYLLARLILLNLSMDNSQNNQEAFSILFEINTLYE
                     EYIGILIKSIWDNSFRETYIQDKSKFLLKNEQTGKKNFNLRPDIVLYDLKNEYEIIID
                     TKWKAIEVDSNVFYRSSDIYQMYAYITAYENAKRCILLYPCIQKDKNYSSWKLSESFK
                     GKFIEAKTVRLDDIKNTKNDLKKIIFNYKF"
     gene            complement(36758..38692)
                     /locus_tag="KR294_001170"
     CDS             complement(36758..38692)
                     /locus_tag="KR294_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBH0239258.1"
                     /translation="MSENIRGTEYWLMEEFFYQETDTPQIFREESIIALGFDIKINLK
                     KVFSMGKKSEKYINENCNDKDFIKKFMSIKKGDYFLYKAYQNIEEKVKCNVSIGIVEE
                     DFENGYELSHILGHTLPVKWMHNFDTVSNCKVYTSEFYKLNNNDISSYLEIIKSQDKK
                     LLRKRIEESENNKWYLKNYYYKNVDKCVDDEELFIQPINLEQLESLKNIKTDDYILLY
                     NSEKVICENDHTMKSLFGVCQVMEGFDKEKVSALEGGYFFPVRWIEYEKENIDGNAWV
                     IFENNSIVEKYVKRFTNKMPLNTILYGPPGTGKTYNTKQMVYNLVSETSLRNKYYTGY
                     LDYKNNVEFCTFHQSYGYEEFIEGLKSDGEGNFKQEDGILKDISIEACYNALKFEKKM
                     SFELEKDSLTLETIKDRKKKLVLENIEYSESFNFEESENYVLIIDEINRGNVSKIFGE
                     LITLLEDDKRLTKSNQTIVKLPYSKEKFSLPPNLYIVGTMNTSDKSIALLDIALRRRF
                     NFEEIMPDYDLLSIVDGIDIRKMLYTINKRIEFLYDRDHVIGQAYLLAVENINDIVVV
                     FRSKIIPLLQEYFYYDSEKVGLILGGIGRNEKDKYIVYKEKLIASELFKNNNASIMES
                     KVNYCIKQNISSEELKNIYE"
     gene            complement(38721..39443)
                     /locus_tag="KR294_001171"
     CDS             complement(38721..39443)
                     /locus_tag="KR294_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein"
                     /protein_id="HBH0239259.1"
                     /translation="MENFNKNAKIIGIGAEGINIINEVEEKIKANMDIEKININQEIE
                     KEYVRSLLDGVDILFLIYSSEDKHIRDIIKAVSYMSNERRVLSIGMDCSEKENKEDLE
                     LGREFKINNDSIFKFVDLMNIMVESISDSCMINIDITDLKEAIVGDKGIKYSFEEFED
                     TKSYSEIADILFDRMEYIGEEFISKKGIVFVEGSPEFSIMELNDLISNIQSKVEESYE
                     VIFSLYIKENLNGNIRVGLLYN"
     gene            complement(39493..40479)
                     /locus_tag="KR294_001172"
     CDS             complement(39493..40479)
                     /locus_tag="KR294_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing protein"
                     /protein_id="HBH0239260.1"
                     /translation="MSKVKRLTDVWIYINDKQKFTIKELSEEFNLSAKTIQRYLKELN
                     KMGLPIQAEQGRNGGYRVLNNSYIPPVIFTEKEVMIILFALKSLQIYNYKLMEIEINS
                     IMRKVSYERKSSIKVGIENIKRYIGFVANDTNDGDFKSSNVTEFFRASSESLILNIKY
                     KCGNQILEKNVCPIGIYLNKGAWFSPAYDCKSDKIILVHIDNIIDIKRTGESKKIHIN
                     LEEWLHEVYNNLYGNSSTTKKFGEIIYLNVLLTKEGVSKIKDSSWNLDMELNEDGSGI
                     ISTFIKVEDIDCYASILFFIGNNAKVIEPKFLNKLLYDKANELRYFYEENMV"
     gene            complement(40536..41036)
                     /locus_tag="KR294_001173"
     CDS             complement(40536..41036)
                     /locus_tag="KR294_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HBH0239261.1"
                     /translation="MRKNSINIALTAAITAIYAVLTLSLGFISYGPIQFRVAEIMMLL
                     AFLDKGYIVGLTLGCFLANVIGPYGVPDIIFGTLATFISASMIYITRKLGKQNKSTLV
                     IASLWPTVINSIVVGLMLNVFFGLPLILSMIQVGFGEFVVVTIVGVPFFCFLMKKYKN
                     VINIKF"
     gene            complement(41322..41633)
                     /locus_tag="KR294_001174"
     CDS             complement(41322..41633)
                     /locus_tag="KR294_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239262.1"
                     /translation="MAGNLNNMRAVNNFRGDKNILECLVSFEGRSISQRKVRVFFKEK
                     QNQIEIDFAEEEISKLVENVVLNTSYQEMLYDEIEKQLEIDCIGTWMILSKLKDGSRV
                     H"
     gene            complement(41773..44037)
                     /locus_tag="KR294_001175"
     CDS             complement(41773..44037)
                     /locus_tag="KR294_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HBH0239263.1"
                     /translation="MNIVGKGIKKIDGMSITTGKPVYTDDLSAKDALVVKILRSPHAY
                     AKIKDIDTSKAEMVDGVECVLTYKDVPKSRFTLAGQTYPEPSPYDRLILEDVVRYVGD
                     EVAIVAAIDEKTAIKAMNLIKVKYEVLTPVLDFEEAIGNKTMVHDEDRHCNFDIGMQR
                     EKNIVSHHDYTKGDVEKVLSNCDVVIEETYYTQAQAHAMMETYRAYNYLDHMGRLVVV
                     SSTQIPFHVKRHLSRALEIPASKIRVIKPRIGGGFGGKQTACVEIFSAIVTLKTGKPA
                     KIIYDRKETFNCSTSRHAMRLKVRLGATNDGIIKAIDIKALSDTGAYGEHASTTIGLV
                     GEKTLPMYNKVEATRFIADVVYTNKMPAGALRGYGASQGCFAVESTINMLANKLKMDP
                     TDLRLKNVVTEGETTFAYGKTLNSVDLIKCINKGKELIGWNEKYPCKHLDNGKIRSVG
                     MAITMQGSGIQGLDKSSAEIKLNDCGDYTLMIGSTDMGTGSDTILAQMAAEVLDTSIE
                     NITVISADTDLVPYDPGSYASSTTYVTGMAVVKAAQDLREKIISAGATKLGVEKDEVK
                     FDGIKLTSKKGSTLLFDIAVDSTIGPDTNQLIGLASHGSPVSPPPFIAGFAETEIDTE
                     TGKVDLVNYVAVVDCGTVINKNLAKIQVEGGIVQGIGMALFEEVRYTEKGRMDTNTFM
                     QYKIPARCDIGNVKVDFVETYEPTGPFGAKSVGEVVINTPLPAIQEAVFNGIGVRINT
                     LPITPEKVFMEMNK"
     gene            complement(44041..44490)
                     /locus_tag="KR294_001176"
     CDS             complement(44041..44490)
                     /locus_tag="KR294_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2Fe-2S iron-sulfur cluster binding
                     domain-containing protein"
                     /protein_id="HBH0239264.1"
                     /translation="MLVKININGKKKSVDIEPEEYLVDTLRKVGNLSVKRGCDTGCCG
                     LCTVLIDKKPTLSCATLTLRALDKEITTIEGLENEVKEFSEVLVKEGAEQCGFCSPGF
                     ILTVLAMKDELENPTDDEIKHYLTGNLCRCTGYMGQLRAIKTYLEVK"
     gene            complement(44490..45278)
                     /locus_tag="KR294_001177"
     CDS             complement(44490..45278)
                     /locus_tag="KR294_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD binding domain-containing protein"
                     /protein_id="HBH0239265.1"
                     /translation="MFTVMDIVQPDTVEEAYSILNKRKTNQVIGGSAFLRMGKKRIGT
                     GIELSKLNLDYIKEYEDYVEIGSMTTFRTLETSSIIKNNFGRIIEDSVKNIIGVQFRN
                     VVTVGATVFSKYGFSDLIVALLSLDTEVELYNIGRISLEEFLNRDYEKDLLIKIYIKK
                     TNKNASYKSLRNAKSDYPILNVSVSKHMEQFKLCVGARPQKATIAKQASEFLSNNEIN
                     EINIDKAVEIASEELTFGSNMRASREYRKAMSKVLLKRAIMEVI"
     gene            complement(45473..46741)
                     /locus_tag="KR294_001178"
     CDS             complement(45473..46741)
                     /locus_tag="KR294_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HBH0239266.1"
                     /translation="MEASIHTIASNNLLIIFAIVSITGIICSKLSEIIKVPDVVLYLL
                     VGILIGPSFLKFIDIRGFQIENQLILTFGSAFILYLGGKEISLKVLRNVKISVFLLAT
                     LGVVISAFIMQQVIGFTFGISAMTALLAGTIIASTDPATLVPIFNQVKIKDRVKQTVI
                     SESAFNDATGAILTSAVLAVILSNKFSLGENIYELGTMVIVGVLVGLITGILLLKLVN
                     DKPYGIFKDFAPIISVISVVVAYELSTKLGGSGYMSCFIVGIITGNKKNFKIWLSQKS
                     YDADFYVAETLGTICRMAIFIILGSQVNLAQLSKYFMPSVITVLVLMFIARPLCVLVC
                     TLVDREAKWSKSEILFMMWVRETGVIPAALCGIISAMKVPGYEVISSVVFMTILITLV
                     IQGSTTKLVAKKLGLLEEEVINISEKVSTF"
     gene            complement(47082..47243)
                     /locus_tag="KR294_001179"
     CDS             complement(47082..47243)
                     /locus_tag="KR294_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III"
                     /protein_id="HBH0239267.1"
                     /translation="MKQDKQNEKQSEISKIKQSNDNKLEIAQELHVSKNIGNMLGYRI
                     DKKKMNRPS"
     gene            complement(47392..>48367)
                     /locus_tag="KR294_001180"
     CDS             complement(47392..>48367)
                     /locus_tag="KR294_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HBH0239268.1"
                     /translation="IPKIIRLVNKTYIFLGILTIIVYMIIESIVTHLIINAVQKTKVK
                     FIGIKMATMGFYYNLVTPFASGSQPMQIYALTKYDVSLSKSVAIVTNKTVVFQSTVTV
                     FCGILILLNKSLLMEQVHSVKVLITFGMIMNVSMLLGGLLIVFSPKQVKMIAEVLINF
                     LSKFKTFKFLDSKRDRINHYIDDYNYSIKIFIKNVRILVLSILLTVLQLIAYFSIVYC
                     VYKASNLRGVSYVHIMTLQVFLYMAISPIPTPGNVGANEVTFFTMFSNIIPKELLGYS
                     VLLYSGFVYYFILIVSGLFTFGTHYTLNSWKKENKVNSNLDKVIEKLN"
BASE COUNT        15042 a         9227 c         4979 g        19119 t
ORIGIN      
        1 tctatctcaa attaataact acttaaataa tctgttttat tttaatttat cgcctcagtt
       61 attatacttt tttacgaaaa attatacttt acaataaaaa agatattccc ttatagaaaa
      121 tatcttttta aatactatat tattatatac ttgctaacat tggaatatct aacatcttct
      181 tcattacatc atctactttt tttgctttat attcattgta tccaattaaa tatccttttt
      241 catatgaact ttttaaaatc tctttttcat ataaattatc agatttggct tctgtgacac
      301 ttaaattata aagcccttta cacccatctt cataaccttt attataccct ttttctgcaa
      361 aatagttttt atgatttttt tcgttatgta ctgaagatat tgttactcca gaattttctt
      421 ttgtactagc ataaggacaa aaacctttat tgtgttgatg tgctgaatgt cctccacaat
      481 aataacgtgt taactctgat ttatttttat tatgatgatc tcctgatgaa ttatgccctc
      541 ctgagtgagc atatgaaaaa ttccctacac taatcatagc taaactaatt actacagcta
      601 ctaacctttt cttaaccata atctattccc cccaaaatgt tatatatttt tattatatca
      661 tctactatat tatatttaaa ttcttaatat acaaaatatt actctattct gctaataaac
      721 atgtttaaac aacataaaaa acctcctaat atttgattaa aaatttacac actcatgcat
      781 agcatgtctc aaatattaaa aggttttata ctaataatta tttatctttt ccatacattt
      841 tagctaattg gtcttgtatc tctttacttt ctaaatactc atcaaagtcc atttttctat
      901 ccattattcc atttggagtt atctctataa ttctatttgc tatagtagat ataaattcat
      961 ggtcatgaga agtaaataaa agcactcctg ggaacttttc aagtccttta tttacagaag
     1021 ttatactttc taggtctaag tggttggtag ggtcatctaa tacaagtaca tttgcatttg
     1081 aaagcattag cttactaagc atacatctaa ccttttctcc tccagatata acttgagctt
     1141 cttttaatgc ttcttcacct gagaataaca ttctacctaa aaatcctctt ataaaacttt
     1201 cacttttttc ttcagagaac tgtctaagcc agtcaaccaa agaatattct actccgtcaa
     1261 aaaacttatt atgatttttt ggaagataat cttgagaagt agttactccc catttatact
     1321 ctccactgtc tggttcaagt tctcccataa ctatgttgaa aagtgcagta gtagctattt
     1381 catctcccat aaatactact ttatcatctc tatccaatct aaatgacaca ttatcaagaa
     1441 ccttaacccc atctatagtt ttagttaaat tgtgtacttc taaaacttca ttcccaattt
     1501 ctcttgcagg tgtaaatcct acatatggat atcttcttct tgatggttgt atatcttcaa
     1561 cttctaattt ctctaactgt ttctttcttg atgttgcttg tttagccttt gaagcattag
     1621 aactaaatct agctataaat tcctttaatt gagctatctt ttcttcagtc tttttatttt
     1681 ggtccttagc cagttgtaaa gccaattgac ttgactcata ccagaaatca tagtttccaa
     1741 cgtacatttg tattttacca aaatctacgt caactatatt agtacatatt tgatttagga
     1801 aatgtctatc atgtgatact attataacta tagattcttc taaatccatt ataaaattat
     1861 ttaaccagtt tattgattta aaatctaagt ggtttgtagg ttcgtccatt aatagtattt
     1921 caggcttacc aaaaagtgat tgtgctaaca ataccttaac cttttcccca ccaactagtt
     1981 ccttcatttg tttgtaatgc atatctttcg ttatgccaag acccataagt attttctcag
     2041 cattagtttc tgcatcccat ccgtcaagct ctgcaaactc accttcaagt tcggcagctt
     2101 ttatcccatc ttcttcatta aagtcttcct tcatatacaa tgcatctttt tctttcatta
     2161 tgttccaaag tctctcatga cctcttataa caacatttaa aacagtttct tcttcatatt
     2221 caaagtggtc ctgttttaaa actgacattc tttctttatc agttatagat atactacctg
     2281 tattaggctc tatttctcct gataatattt ttaaaaaagt agattttccc gcaccattag
     2341 ctcctattat tccatagcaa ttacctttag tgaattttaa gttaacatct ttaaatagtt
     2401 ccttatcacc aaatctaagt ccaacacctg taacttgtaa cattaatata ttttcctttc
     2461 tttttgctca taatttattt tatcataaaa ctttgataac atttttatta tatattatca
     2521 cgtaaatagt atatttttta tactaaattt gtgaaatatt tattaaaata atactaaaaa
     2581 ttgtaaattt ataaaaatta acaatctctt atattatact tataaagaaa tcaaattgca
     2641 actttattca ttcttttaca cattgaaaat aagttattat aatttctaaa taaatatgct
     2701 tttcttaaaa catcattcta gctgttttgt ttcatattta aaaagagtac ttaatttgta
     2761 aatactcttt tttaataact ttatatttta gcaaaattac atgcaggata agtacataca
     2821 tcacagttca tacaaaggcc accatgacca tatctagcta tatcatactt atcaagcttt
     2881 tcatcaatta aaaccctaga taaaactata tcaaatactg tagttttgtg atacattgcg
     2941 catcctggta tacccataat tggaacttct ccataataag caagtaaaaa catagctcct
     3001 ggtaatattg gtgaaccata tgtcactaaa tcagctccag tttcttttat agctgttggt
     3061 gtaacatcat ctgggtctac actcatccca ccagtacaac agataagttc tgctccttga
     3121 cttataaatt cttttattgc actctttata atttctttat catctgggca tatagtctgt
     3181 cctataactt cacaaccaaa gccttttact ttttcttcta ttacgggtcc aaatttatca
     3241 acaattctgc tataaaacac ttcatttcct gtagtaacaa ttcctacttt cttaggttta
     3301 aaaggtacta catttactat ttttctatta ccaactactt tttttgcatc ttctaatttt
     3361 ttctcatcta taactaaagg tatcactctt gttccagcta cttttaaacc tttatttact
     3421 ataaaattat tatgaagagt agccatcatt atttctccaa cacaattcaa atcaaaaagt
     3481 gcatcaacat ctatctttaa tagaccatca catgctgcta taaaatctat tttcccttct
     3541 tttatttcac taaaatctaa attttctcca gcagttagtt cttttaaaaa caatgcgcct
     3601 tcattttcat gaaccattcc ttctgacttt tcccatacat acaaattatc tttaccaaga
     3661 gataataaca ctggaatatc ttcttctttt actatgtggc cctttttaaa ttttcttcct
     3721 ttaaattctc caggtattat ttgagttatg tcgtgacata aaacttgtcc aacagcatct
     3781 atagttttta ttagcttcat aatttacccc caattctctc ataatccatt tttgtatcga
     3841 tatcaaataa catttcttta ggaacttcta catactttat ttttgatgaa ttttttaaaa
     3901 tggttttacc tttttcatct tctttaagtg ccaacaattc ttctttctta ctatatggga
     3961 atatgactgg atttccacac atatctttgt atcttggaat tactataaaa tctctatcta
     4021 atttaaaagt atttataatt ttatctatat ataagttatc aataaatggc tggtctccta
     4081 caaagaacat ataaccatca cattttgagc tatttaaaac tcctaatttt atagattcac
     4141 tttgacctat atttgcattt ttattatcta tatattcaaa accatattta ttacacaata
     4201 acaaaacctc ttcatattga cttactacta caacttgatg aaaatcaatc ttgctaactt
     4261 ctctaaatac atgttctatt atagaacagc ctttataatt taataaaagt ttatttgctc
     4321 ccattcttct ggcaaagcct gatgccatta tcactgcatt tatcatatat atcatccttg
     4381 gtatttataa tatattgata gttctatgat ttttataata tctctattga tattatctat
     4441 atatataata tcatataaac tattttaata cttcaatatc ttacacaaaa tttttgtttt
     4501 acacttccat aaaatatctc tatttcactt tcatattctt taatattttc tactaatttt
     4561 atagctaaat ttttatattt ttcattttca actttattaa taaataatac tctttttcca
     4621 gaataatttt taaataatcc atttggattt aatactatat tttttaagtt ttcaatactt
     4681 actgtagaac tactattaat actacttgta tctaaatttg ctattttttt aaatatttct
     4741 actctatgta tattctcttc attaatattc attccaaatg atgttatatc taatatccct
     4801 atggtttttg tagttttatg atatactact ggttctttag cattccaacc tttaagtttt
     4861 tttctctttg agccatctcc ctctattaaa actaaatcaa attggtctac aatttcatcc
     4921 aaaatagagg aatcaatact tactaattta ttttcattat ttatataact gccacagact
     4981 gttattccat gacaaataga tggaataaca gttccatcta ttgtaataat tatattgtca
     5041 taatcgtttg gtacatatat tttagttgtt gttgtaagga gaactttcaa tttatctcta
     5101 taaaaatttg caaaatagtt tataaacgaa gtttttcctc ctgctccaac tacagttatt
     5161 atttcattct tttctattat atttgatagt tccacacttt cacctcttat aaccagtttt
     5221 ctaatctctt aattattata gttagacctt tttagtaaaa gtgatttttg aaattccata
     5281 aactcgaaag taaatagatt ctgttgtaaa caacaaggcg gatccaattc gccgctaagc
     5341 tgtaagctta cgctatcagt ttatctttta aatataatta agatattctt actctctgtg
     5401 gttgctttaa tatttgagga ttattctgta aattagataa attaactact tgtgattttt
     5461 ttagtatatt aagactcgca tttacatctg catttataat gattccaaca ctggatttgt
     5521 actgtccacg cgttattctt tcccctttaa agtcatattt tttaacattg tccacattga
     5581 tatcaggtag aaaatcatca gcaaaaaaat ctgatttact agtatagctt tcttcttgcc
     5641 taataaaatt gatatttttt attttacaca gatattctaa ttttcctttt atctctccaa
     5701 atgggattct tataaaattt ctatatattt ttctctccat attatcactt ttttctaact
     5761 tagcattata tcctacaatt aaatttccaa tattattttt tacacaataa tcaattatat
     5821 aaaaacaggt tttatttaca tagtctttaa cttgattatt tctcttattc caaactttaa
     5881 attgttttct tgttattgca gttatattct tttttaattt taaggcttct attttatcat
     5941 tctgtttgtt tgcccactga ttcacagatt ttagcctttt tccatctatg ataaaactat
     6001 cacctaaatt ggtaacacat gtacataaat tttctaaacc caagtctata gctagtgcat
     6061 ttttttgatt tgaaacttcc tctgattttg gtatttcata acaatactga atttcaaaga
     6121 acctagcttt atgtttaggt attattctta tttctttaat ttttttctct agtatatttt
     6181 gtggaacttt tatacttact ttcccatata gttttttaaa tgctggagac ataggtacat
     6241 ttaaaatccc atcttctttg attcttattt gacctattat tatgctaaaa aatccttctt
     6301 tatctaaata tttaggtgat tttatccctc taaagtcata ttttccttct ttggctaatt
     6361 taattaatcc aaaaaatgac ctaaacgaac tgtctacttc ttttaatatt tgttgcgcta
     6421 tattactatt gagaagctta tagttctcat tttctttgca tacatgataa ttagcttcat
     6481 agttaagatg ttctccttga ttgaaataat gctgtcttac attatatgta ccaacattat
     6541 ataagttctt agctaagaag cacatctctc gtagagcttg atattctttt ttagttaagt
     6601 tttttaattg ttgtctctga gttccatagt gtatattttt tattctgttt gacatgaact
     6661 cacctccttt agaatatact ctactagaca ttatatacgg tatttttaca aaacaccata
     6721 tataatgtcc atttaattac tttattttac aaaataattt aaatttactt gcttttatac
     6781 acattattat ttattataat tgtttattat tatttttcat acccatataa actttttcaa
     6841 aagtcatagg aagctctctt aaacgaactc ctgtagcatt aaatattgca tttgctatag
     6901 ctggtgctgg tgtatgtata actatttctc ctaatgattt agcaccataa ggacctcctg
     6961 ggtcgaaatt ctcagcaaaa tctaccaata tatttccaac ttcttttttt gtaggaactt
     7021 tatactgtag gaaactatct gttaataatc taccatcttt atcaaatata gggtcttcat
     7081 acattgcaaa ccctataccc atcatcacac caccttctac ttgtattcta gctaaagttg
     7141 gatttataac tgttccacaa tcaggtacac atgcaaaatt tatgacttta tattcgcctg
     7201 tatttttatc taattctatc tctgcaaatc ctgctataaa tggttttatt tttttcaaca
     7261 tgccaaaaga ttctgttgct tccaaaacta ctggtacatc atcactagca aatcctattc
     7321 ctccaacaga ttctctaccc aattcctcta atagaacaaa cttgctatta tcgtttttaa
     7381 caaaaaccct gtcttttccc aactctaaat cttctttttt aaatcctagc tttgactctg
     7441 caactgaaag taatatatct tttaatttat ttgctgtctt tattgttgca tttcctgtaa
     7501 ccgttgtcgt acaagaagca aatgctcctg tatcataggg acataagtct gaatcacctg
     7561 tataaataga aattctatct acagtagtat ttaaagcttc cgcagcaatt tgagcttgaa
     7621 ttgtatcagc cccttgacct aagtcagcaa gaccagataa tagtttatat gtgccatctt
     7681 catccattct tatagtgact gttgccatat ctacacgcgg tataccagaa ccatgatttg
     7741 ctactgccat acctactgct cttactttgt tgtttcctat atctttacat ggatatttat
     7801 catcccaatt aattaatttc ttgccctttt ctatacattg tctcagctca caacttaata
     7861 tttcgtcttc agctgctttt ccattggtat acctatctat tatattttta attctaaatt
     7921 caagtggatc cattccaatc ttatgtgcca attcatcaat agcactatct attgcaaata
     7981 ttccctgtgt agcaccatac cctctaagtg ctcctgctgg taacctatta gtatatactg
     8041 ttctagcatt aaatctaaca gcatcaatat cattatatat tggtaaggta ttgtgtccag
     8101 attcggaaga aacagagaca ccattcccac cataagcacc tgtattgttt aatgacttta
     8161 gctctattgc ttttaaattt ccttctttat ctgcaccaac tttaacatca aaaaacattt
     8221 catgtctact attagaacct acaaaagttt cacttcttgt aaatacaaat tttgctggtc
     8281 taccagtttt catagtaaca aatgcagtaa atatatctgt tgctgctata ttctttcctc
     8341 caaatccacc acctattcta ggtttaatta ctcttatttt tgaagatggt atacccaata
     8401 cttttctaag tattctcttt acattgtgtg gtgattgtaa tgatgaaact acaacaattc
     8461 tatcatttat atctttatat gaatatgacc tatgagtttc catcatgcaa tgcgattgac
     8521 tttgggtttt gtatgaagat tcaaccacaa aatcactttc tttaagctta gcttcaacat
     8581 ctccaaattc aaaaaattct tttgatacta tattattttt tgcatccaat ccaaaaggat
     8641 atggctctac tatgtctttt tctggatgta taacaacttc atttccttct gcttctcttg
     8701 catcaaacac aggctttaaa acctcataat ctacctttat catttttaag gctttaagtg
     8761 ccgttttctc atcttcagca gccactaaag ctacttcatc tccaataaat ctaactgtat
     8821 cttcaagtaa aactctatca taaggtgatg cttctggttc tgtttgacct ggcacacaat
     8881 atctgacctg tggtacatct ttatacgtat aaatacccac aacccctgga attttttcgg
     8941 cttttgatgt atctatattc tttatcttag catgagcatg tggacttcta agtagtttta
     9001 atgtcaaaac atctttatgc ataatgaggt cttcagtata tagaggtttt cctgtgacaa
     9061 ttgctgtact atctatcttt cttatcccct tattaatcat tatacattcc ctcctcaata
     9121 gcattataca tccttttaac taatgcactt gccatatcct ttctgtactc tttactagct
     9181 ctcatattac ttccataagt aagttcctta ctagcaacaa tagatgcctt atctatatct
     9241 ttttctttat ttaatatatt actcgcttca agtgctaatc tagctttttg aggtcttgcc
     9301 ccaattgcta ttttgtaagt atcattttct tttagcattg ctgaatttaa tacagaaaaa
     9361 tctcctgtgc attttcttat tgagtcaaaa acagctattg catctttttt tggtagtatt
     9421 acttcgacca atatatccct acttaattca ctatccaaaa actcacttaa ctctagtatt
     9481 cctttattgt ataatctcac cttcgctcca acaaccaaaa gcgctggtat taagtcagaa
     9541 aagccatact ttgaaaatac acttgcacca attctagccc cttgtctaaa ttgaacacca
     9601 actatattag aaacagcgct tgaaagtatt ccactacagt aattttttat agttttatca
     9661 atttctaaac ttctaagtga agtatctgca cctatcaaaa tatttttttt atcctctttt
     9721 atataattta gatttatatc ttttaaatct atcgctgttc ctatattttt attacttaat
     9781 tttataaatc cacatccacc taaaataaca ttattttttt tagaaattaa aattttatat
     9841 gcttcttcta aactctgtgg aactgaatat tcctttatag taaccatctt atccccccat
     9901 cattaactta ttaaaacaca aaagttttta ataaatcttt tatttatatt tataattgta
     9961 gtatatttaa ttcacatata ttaaaccttt acattataaa cttttatttt tatcctcaac
    10021 cttatcactt ttatttccag gaaattttac catatataaa gcttgaatta ttatggctac
    10081 cattgctcct gaaactacac ttgaatctgc aagtaatgtc tctataaatt ttggaaattt
    10141 ttcaagaact tgaggagcta ccatgaatcc aataccagaa gccatagaaa gacctaatat
    10201 catgctattt tcttgattaa atccatccat actaacaagt cttaaaccag atgttgtaag
    10261 agttgaaaat ataacgagtg ttgctcctcc aaccacacag ggaggaattg ttcttattaa
    10321 attagctaat aaaggcgata ttcctgccaa aaataatcca attcctccaa tagctagtac
    10381 aaatttactt acaacctttg tattggaaac gattgcagaa ttttgtccaa acatccccat
    10441 tggagttgca gaaaataatg cacctattgt agagagtact ccatttccta aaacagcaga
    10501 agaaagttct tcatctgtta cttgtctatt aagccctcct accgcagaaa gtgtacaagc
    10561 acccattata tcagctatct caactaaata tattattgaa aacattacaa caacttcaag
    10621 tcttatatct agcccaaaag caagtggttt tggaagtgca accaaagtaa actcctgaat
    10681 tgaagaaaaa tttactatac ccaaaattaa tgataaaatg tatccaaaaa ttatgctaac
    10741 taatattgat gcatctttaa ataatccttt tccatactta tttaatccta atatcataag
    10801 agatacagat attccaacta taaaattaat tggattccca aaagtctcat tgcccatacc
    10861 cccagctaag ttttttatag ctattggaaa aagtccaaga cccatacatg caactattgt
    10921 tcctgataca gctggagtaa atataaatcg tattttttta agaccaaaac caattataat
    10981 tattactata ccagctatta tttgagagcc aaataatact ggtagtccat acttacttgc
    11041 aacagatacc ccagctccta taaacatagc tgtagctccc attataactg gtattcctcc
    11101 tcctaattta aaacctttaa acaaaggtat tggatataat tgtaataaag ttgataatcc
    11161 tgcaaaaact aatgcggctt gaatcaataa tgttgacatc ttatgattaa gtccagctgc
    11221 atttgcaatc aatatcgctg gtaaacaact acctattacc attgccatta agtgttgtaa
    11281 ccctaaaggt attgcttcct ttagtggtgg tattccgtct aattcaaatt ttgatgtact
    11341 ttttgctttc ataataaaaa ctcccgttac ataaaactta ttgaattata taaatactta
    11401 aaaatctaat atattaaatt aatgatgttc ataaatatca actatactcc aacatatatt
    11461 taagttttta gtcttaaaaa acagatgcaa taaatttaat tattaacaaa taaacgtatt
    11521 ctttaatttt gtatacatta tataccatgc tttacaaata taagagtatt atagctatga
    11581 atttttaatt ttttatagta aatttaattc aatttaaatc tttcaatctt aatcattata
    11641 agttataagt tttcataagt atttacatgt ttcaagtttt aaacatttac ctataaacgc
    11701 tactttatag atgtcacttc aaatccagtg acctcatact ttcatatgag cgtagactat
    11761 ttcttcatct tcagcattac ctgctaagag caacccgttt ccactatcaa tcgcttatag
    11821 tgtactctct ctcgagatag tcgtttgacc ttcctatttc taggcttggc gaccaaatgt
    11881 ccatttttaa gtacttaggc tctcaccata taccatcctc actattgttt ctggttttca
    11941 ccacattcat aaaagtttct ttctatcttt tattgtagtt gcaaggcttt aggatttact
    12001 ggttttaaag ttgtgtccta catagatttc tctatgtacg gggccaaaag tacaatttat
    12061 ttaacatact ttgctttacc ccctgtaaat aatattattt actctttcac tgtttttgtt
    12121 attaaattaa ttaaatatca attaatctaa gcataaaata attatttaat ttaaactcaa
    12181 aatatttatg aatattttat aatataattc tcataagaca gaaaaactta ataagctatg
    12241 tatctcagtt gtaccaatgt actctccttt actatatttg tatctgcaac ataaaatata
    12301 caagtttcta tctatttata gatatatata tctataagca aaatagtaat attattttta
    12361 atagtaaaaa ttttattcat attactattt ataattttta tagagcaatt ttagtgccaa
    12421 tatttgcata catttgtata gtataaaatt tttatgttct cattgataaa attttactta
    12481 tttcaagcgt tctattagat tttatcatct aaattttagg ttttattttt ataaattaat
    12541 tgtatttaca taaaaaaaaa gacctaaaaa caaattttta acggtctttt ctcaattttt
    12601 tattttcatt tctaaaattt ataataaata gtaagaacac tataaattct tttatataaa
    12661 attcttaatt tgtggatgat aaattagtga attaaaatac tactttactg attttagttt
    12721 gacaatatca ctccaatttt tactagtggc taactctact aaatttaagt ctcttcttat
    12781 ttcagctata tcctctttta tagaattagt gtcacctttt atatatgcta tgttatgttc
    12841 tatattatca tgagtagctt tatttatttc agaattatgt aataaacttc ctaaaatatt
    12901 attctgttct atctgtatct ctttcattga tttatcttca cattctagac tatcaatctt
    12961 aatttcaatt ccatataatt tttcatttgc tatggatacc tcgtccttaa ttccattcat
    13021 atcttcatta atgttattta ttttattttg cataaagttt acttctgatt taacttcgga
    13081 aacatcttct ttcattacag ttatttcttg tctcacttct gacatgtctt ttttcattac
    13141 atttatctct tgttttacct ctgatgtatc ttctttcatt acagtcattt cttgtcttac
    13201 ttcggacata tcttctttca ttacagtcat ttcttgtctt acttccgaca tatcctcttt
    13261 cattgtattt atctcttgtc ttacctcaga catatcctct ttcattatat ttatctcttg
    13321 tcttacctcg gacatatctt ctttcattac agtcatttcc tgttttactt cggacatatc
    13381 tacttttaat acatttattt cctgttttac ttcggacata tcttctttca ttacagttat
    13441 ttcttgtttt acttccgaca tatcttcttt cattacagtc atttcttgtt ttacttccga
    13501 catatctcct tttaatacat ttatttcctg ttttacttcc gacatatctt ctttcattac
    13561 agtcatttct tgttttactt ccgacatatc ttcttttaac acatttattt cttgttttac
    13621 ttccgacata tcatttttta tgctaactac atcttcattt atagtatata ataactctaa
    13681 aatcttctct tgcacttgca tcaccatccc tattaattat tataacattt tacacaaatg
    13741 ctatacaatg ttaacatata tatcagaatt attaaaattt taattaaaca aaattgattc
    13801 actttattac ttcaaaacta attaatatct aaaataacta caaataaaca aaaataaggt
    13861 caacaacaaa aaaggcttat ctctttgaga tagcctttct tatttttatt taaaactttg
    13921 ttttttataa aataatctat acattcagct ctgaacatga aatttttctt ccaagtgctt
    13981 ttggtttaca aactgatata caaagtccac aatatctaca ctcttcttca ttcaattcca
    14041 tcttatcatt caattttctc gcttgatatg cacaaactct ctcgcacatc ttacatttag
    14101 tacatttttc ttcatcataa gtaaactcaa agctaagtct ttcattaaca tctcccatat
    14161 gattatgtac tataccacaa gcattttcta tagtattata tcctaatcta ttaagattag
    14221 attttaaatc atcatgtatt ttagatatta cttgtgcgcc ttttaaaatt actactgaac
    14281 atataccaac aaagtcagca cctgccataa tcatttctaa ggcatcatct ccacttacac
    14341 atccacctaa gccaattatt ggtatattaa cttgtttttt tatttcatat attctctgta
    14401 aagttattgg cttgatagtt tctccactta aatatcctat tccatttcca cctaataaag
    14461 gttgccctgt ttctatgtct attctaaatg ctggtcctac agaatcacaa gcagttattg
    14521 catctgctcc tgcttcttct aattttttag caaaatcgcc tatctcatct atcataggag
    14581 gaagtttaac tattacaggt atatttactc tttcctttgc atctttaagc attggtatca
    14641 aatctctata gtcataagat actaattcaa taaagtcagc tcctgcattt gcaactttct
    14701 ctactaattc gctactttct tcaattgtat gacctactga agctatacag acagtcccat
    14761 ctcttttcat ttgtggtatt tcaaaatcta tccattgctc tggctcaaaa tctgtccatt
    14821 tttcattatt taaaagagca ttagctgtat ttctaaccat atgtggtgct ggatttatag
    14881 ctctttcttt tcttatagtc ttagtcacaa ctgcccctgc tcctgcatca cttaatatct
    14941 tgcatccagc tgcactatat gttaatggtc ctgaacctat tataagtggt gattttaatt
    15001 ctttacctaa aaaattatac attatctgct tccccttttc atatatattt acattcgtta
    15061 aaatttccaa aattcacaag caacttcttt catttcttta acaatagctt ttttatctaa
    15121 atcaactaac tgtttttctt ttaaaatatg tctaccatct atgtatacat ttgatataaa
    15181 ttctttttta ccctgaacta ctatctggtc aaatatatta tcaagagtca caggagtttt
    15241 aaattcatct tccataacta ttatatcagc cttattacca actgctattt taccagaatt
    15301 ttgaagtcct aatacataag caccatgctc tgttgccatt ctaaatacta aatttgctgg
    15361 cattactgat gcatcttctt caactgattt atgcattaaa aatgcacctc tcataacttc
    15421 aaaaaaatca tttatatatc cgtcagtacc cagtgccact tttatacctt ttttaatcat
    15481 ttttggtact ggagaaaaac ctccacctac ttcacagttg ctaagaggca tatgaaccac
    15541 ttttacacct ttttctttta atatatctat ttcttcatca tttactttta cacactgaga
    15601 tgctaataca gtttcatcca atatatctaa atcattatag tagtcaactg cttttttgcc
    15661 aaaatgtttt tcagcatagt ttggctcata tatactctca cataaatgaa attgcattgg
    15721 tgcatttaat ttttttgtat cttctttagc tttcttaata aatctatcag aacatgtgaa
    15781 gcttgtatgt gtacacatta ttccatttat taatttacta ttttctctac tccactttat
    15841 taaattagaa ttttcattta aacatctaag tccattttca aagcttattc tttcacaact
    15901 ttctaaggat aaaatcgctt tcatgcctat ttcttctagt atttttcctt gctcaattaa
    15961 agttccttct tctgtatttg gagcttctag ggtatcacaa aaagctacca caccagattc
    16021 tataagttct attgctgatg ctttagttgt tgccttcact tctttcaatc caattctatt
    16081 ttctataaat ggccaccaat agtcatttaa gaaaccttca aagtcggtaa aatgtacatt
    16141 tgccggtatt cccctagaaa gaactccata ttgatgcata tgaccattga cgaatcctgg
    16201 cattattata gcatctgatt tatctattat ttcttcaata tttttatatt ttatttcaac
    16261 ttcttcattt ggcaatatat cttttataat gtcattttct actacaacag cagaatttgt
    16321 atatatttca tcagcagaag atattaagta tttactttta atagcaatca tttatttacc
    16381 tccctgattt aattttttca tggccatata aactttctca gaagttatag gaagttctct
    16441 tatacgaact cctgtggcat tgtatattgc atttgctatt gctggtgcag gtgtatgaat
    16501 aactatctct cctaaagatt tagctccata tggacctgtt ggctcataat tatctacaaa
    16561 atcaacaatt atgtttccta tatctttttt tgttggaact ttgtattgta atagattaga
    16621 agtttgaagc tttccatcag aaccatgtct agggtcttca tacattgcaa gccctatacc
    16681 ttgagttaca ccaccttcaa cttgtattct agcaagtgca ggattcataa ctgtaccaca
    16741 atctgtagaa caagcataat ttattacttt aaactcccct gttgttttat ctaactctat
    16801 ttcagcaaat cctgctaaga atggtttagc actctcttgt ataccataag attcagatga
    16861 atataaaact tcttgatttc caccaccaac agattctttt cctaattcac ttaacaaaac
    16921 aaacttctct acatcttcac tataacaaac tctgtcttca tatagtatta aatcatctat
    16981 tggtaaatcg agtttcttct gtgctacttt taatatcttt tgttttaaac tttcagcaga
    17041 ttttattgta gcatttccag ttacataagt agtacaagaa gcgtatgcac cagtatcata
    17101 tggacacata tctgtatctc ctgtataaac ggaaattcta tcaatagatg tattcaatgc
    17161 ttttgcagct atttgtgcaa gtattgtgtc agaaccagtt cctaagtctg aagacccaga
    17221 aaacaactta taagttccat cttcatccat cctcatattt actattgcca tgtctatgtt
    17281 ggctatacca gaaccatgag ttcccacaga cattccaaca gccctcacct tattgtttcc
    17341 aatatcccta acagggtact tttcatccca tccaataagt tttttacctc taattataca
    17401 ttcatcaagt gcacaacttc ttattggaaa attcattatt ccgccttcag tttgtttttt
    17461 tataatattc tttaacttta tttctgttgg gtccatatta agtttatgcg ctaattcatc
    17521 aattgcacaa tcaagtgcaa atgtaccttg tgttgctcca tatcctctta atgctcctcc
    17581 tggaactaaa ttagtatata cagttctccc atcaaatttt attgcaggta cattattata
    17641 tgttggaagt acattatgac ctgattcaga gcaaactgaa ggtccattat cgccataagc
    17701 gcctgtattg ttcaatgctt tcatatctat agcttttatg tttccttctt tatctgaccc
    17761 aatttttata tcaaaaaaca tctgatgtct agtattagtc attgcaaaag tttcttctct
    17821 agtataaatt agttttgctg gtctttttgt catccaagtt acaaatgatg catatatctc
    17881 tgttacagct atgttttttc caccaaaacc tccacctatt cttggtttta ttactctcac
    17941 ttttgaaaga ggtattccca gtgctttaga aacctgtctt ctcatatgat aagctgattg
    18001 gtttgcagaa gttactacta atctgccatt cgtatctata tacgtataag ctctatgagt
    18061 ttccatcata caatgggctt gtgattgagt catataagaa tgttctacta ttacatcact
    18121 ttctttaaac tctttttcta catccccttt acccattttt tctctcgata caatattttt
    18181 tgtagcatcc aatccaaaat caaatggaca aaacaaatca tcttcttcat ggattaaaat
    18241 tttatttcct tccgattctc ttgcatccaa tataggagtc attacttcat attcaacttt
    18301 tataagtttc atagctttaa tagcagccct ttcatcttca gcggctatta tagcaacttc
    18361 atctcctaca tatctaacta cgtcttcaag tattaattgg tcatgaggtg atgcttctgg
    18421 atatgactct ccaaccattg aatatctata atttggaaca tctttgtaag tgaatatgtt
    18481 tactacacct tttaccttta atgcattttt tatatctatg ttttttatct tcgcaaaagc
    18541 atgtggactt ctaagaagct taattgttaa aacatcttta tgaaaaatta aatcttctgt
    18601 atatattggt tttccagtaa caatggcttc actatctatt tttcttacct ctttatttac
    18661 catcacactc acctccaata ctattataca ttctcactac taaggctttt gccatatctt
    18721 ttctgtattc tttacttcct cttatattac ttccaaatga aagttcttca cttgatactt
    18781 caccagcttt ttctatatca ttttctaaac ttaatatttc acttgcttta taggcaattt
    18841 ttgctcttct tggtctagcg cctatcgcaa ttttataaat acttccttct tttaacattg
    18901 ctccatttaa tactgcaaaa tcacctgtac attttcttat agaatcaaat acacctatag
    18961 catctttttt aggtaatata acttctatta atatatcttt ttcaagctca ttttctaaaa
    19021 aatcagctaa gttcataacc ccttttttat ataacttaac ctttgcatct accactagta
    19081 atgaaggtat taaatctgaa aatccatact tagcaaatac gctagctcct actctagctc
    19141 cacttctaaa ttgaactcct actatattag aaacagcgtt tgaaattacc ccattacagt
    19201 aatttttaat aaccttattt aattctaaag ttcttaaact tgtatctgct ccaattaata
    19261 tgctatcatc agtttcattt atataatcta aagctaagtc ttttaaatct attgctgaac
    19321 caatattttt actacctagt tttaaaaatc cacatcctcc aagtattatg ttgttttttc
    19381 ttgatattag cagttcataa gcttcatcta aactttttgg aactacatat tcctttatag
    19441 ttatcatact ctctccccat atcaacttaa ttttcactta aaagtctaag tgtttaaata
    19501 tttatgtatt gctcttaatt gacctttata tcctgtacat ctacaaaggt taccatttac
    19561 ataatctata acttcttctt ctgttggatt ttgaagctct cttttcattg ccaagaccat
    19621 cattataaat ccaggagcac aaaatccaca ctggtcagcc ccttcgtctg caagaaaatc
    19681 tccaaacttc tttgcttcat ccaagacacc ctcaagtgtt gtaatatgct gaccttctac
    19741 tctagcagta agataattac atgaaagcac ggccttgtca tttaccatca ctgtacataa
    19801 cccacatgag cctgtatcac accctttttt aacacttaca tatccatttt ctcttaatgt
    19861 atctgctaaa aaatcatctg gtcttatact taattctttt tctttattat ttatggtaca
    19921 tttgataatc aaataaatca cctcaaaact catattttta agctaaagtt ttactatact
    19981 tttttatgaa taaattacat ttattaataa aggctattcc atttatgacc ttccattcta
    20041 ttttttatag ttcctcttac acaaagtctc tcagctgtat cttgagcatc ttttaatgct
    20101 ttctcttcat tagctgtcaa tatttttgaa tcttccatta ttatatttcc atctactata
    20161 acactctcta tatttttcat actagaagaa tatactaatg tagataccgg attatgcata
    20221 ggtatcgctt ttggtgaaag cattggatta aatattaata agtctgcttt tttacctatc
    20281 tccaatgaac ctatctcatc ttccattcca atagctcttg ctccatctat agttgccaac
    20341 tcaagaactt tttctgctga cattgctaat gggtcacact tattaacttt atgttgaagt
    20401 gctgttaatt tcataagttc aagcatatct tgagagttat tactagcggc tccatctact
    20461 cctaaactaa ctgttattcc ttttttaagc atttctggca ctggtgcaac acctgaagat
    20521 aagtacatat tacttgctgt attatgagac actttcatat cgtatttttt agtaagttcc
    20581 atatcttttt cagttagata cacacaatgt accataagca catttggtcc aagtattcct
    20641 aatttttcta aaacatctat gtcatattgc ccatgcaatt cttttgctgc ttctctatca
    20701 aaaggagtct ctgatatatg tactgtaaat aaagcatcat catattcttt tactactctc
    20761 catagcattt caagcatttc ttgagaattt gaccatattg ctgcaggagc tactcctatt
    20821 ttgattcttc cattttctgt attatggtgt ttttcaaaca atcttcttac atctttttca
    20881 accgtttcta catcttgcat tattccagga tgaactccaa attgagctcc tgtattcata
    20941 catcctcttc caagtattcc tcttattcct aattctttat aagcatctat tattccatca
    21001 caaagacctg gcttactatg aggatacatg tagtcaacca ttgttgttat accacttcta
    21061 agtccttcaa tacatccaag cattgcagca tcataagtat cttttggctc taaatagtta
    21121 gctgctggaa atgtcatagt ttctaaccag tctttaagta ccatatcatc tcccaatcct
    21181 tttaataaag tttggaataa atgattatgt gtatttataa aacctgggaa taaaacttta
    21241 cctttagcat ctataatttt tttaacatca gtatatttac tttctatctc tttagaattt
    21301 ccaatatcag caatcttgtt atcttttact actaatgccc catcaaaaat aacttctctc
    21361 tctttattca cagttactat tatggcattc ttaataagta tatccatcat tcttatttcc
    21421 ccccgcatta tttagtaatt tttcttttaa tatattgacc tgttggatgt tctttaacat
    21481 tacaactttg tactacatga tttcctctca aaaatacatc ttcaacttta catttaacct
    21541 taaatccttc atatggagta taatctacat tttgtttttg agttttataa ctaattgttt
    21601 cttctttatt gatatttaaa atgactatat ctgcatcact tcctacagct atctcacctt
    21661 ttttaggata cattccaaat atttttgcag cattcgtaga agtaacttcc acaaacttat
    21721 ttgcacttat tctattttct aagactccat atgtatataa aagtgctaac ctatgttcaa
    21781 caccaggtgc tccatttggt atcttactaa aatcatcaat tcccaagtct ttttgcccct
    21841 taaaattaaa tgaacagtga tctgtgccaa ctgtttgaat atctccacta gacaatcctt
    21901 cccaaaggta atttatgtct tctttttttc ttaaaggagg agacattaca tacttagcac
    21961 cctcaaattt atccttatta tataaattgt cttctaataa tagatactgt gggcatgttt
    22021 ctactatcat atctatattt ttttctctag ccatttttac agtttcaagt gactccctac
    22081 aacttaagtg gactacatag gattttgaat tagataattt agttatatca gcaagtcttg
    22141 aaacagactc tttctcaact atgttaggtc ttgtaagtgg atgatatttt ggctccaaat
    22201 taccattttg tatattttct tctatcaata catctagtaa atccccattt tcacaatgaa
    22261 atccaactat acaacctaaa tcccttgctt tctttaaaac cctgtatatt gttccatcat
    22321 ctactttcat gccatcatat gccatataca tcttaaaaga tactatccca tccgaaataa
    22381 gtttttccat atgattaaat gtatctttat ttaaacatgt aattgtcata tgaaaaccat
    22441 aatcacaata acaatttcca cttgcttttt tatgatatgc ttctacacct tgcagtaggt
    22501 tttccccctc attggcttct gcaaaatcta gtattgtagt agttcctcca gctatagctg
    22561 ctcttgttcc tgtttcaaaa ttatctgcag ttgtaataga acctgcattc atatcaaaat
    22621 gagtatgtgt gtctattcca ccaggaatta caattttacc tgtagcatca ataaccttat
    22681 caccatttat ttctaagtta tttcctattt caactatctc ttcatcttct atccttaaat
    22741 cacttatata agtcttatca gaggtaatta tagttccacc tcttagtatt gttcccatat
    22801 atacctccta acttttaagc tttaaagtat tttctaagta ttgtaaaact ttatttaaaa
    22861 ttgtattttc taaaggtgct atattcagca cctctagact atatttaaat aatttattgt
    22921 gaactaaata ttattttccg tatacagatt ttaatattcc atagtaacct tctgttccta
    22981 taaataactg ttcttgctct atatactcat ctattgtgtg agcaagattt tccttagaag
    23041 gaccaaatcc tatagttttt attccagctt cacctgcata gtgacttcca ttcgtacaga
    23101 atgagtattg agttatttct gaatctattc cagcttcttt taatccctta tatgctgctt
    23161 gaacaaattc atcttcttcg tcatataacc aacctgggaa gaatctttca ctttctatag
    23221 tatttcctgt atagcaatca gctttttcaa ctgcataaga aacttttgca tttaattctg
    23281 ggtcttcttt catcatttca tctaataaag cttgtattgg agctaatacg ccttctcttg
    23341 tttctccaac taataatctt ctatcaaaag tagctttgca ataatctggc actactgatg
    23401 ctcctggata tggagaagat tttatatctg ttaaaactaa tattccatca cctaaaactg
    23461 gatgagttgg aggtactaat tgttgtatct tttggattac attagccatt ttataaactg
    23521 catttacacc tttttctgga ttagcagagt gagctggttt accaaaagtt tctactacta
    23581 tttctcctct acctctctga ccaatcttta agtttaactc tgaagactca cctattacaa
    23641 catagtcagg ttgaacagcc ttacttatct ctctagccga aacaccttca aatatttctt
    23701 catgaacaac acctgctaca tatagttctc cagcaaaatc tctattagtg tctttagcaa
    23761 aatacgctac agcagacatc attgcagtat attgaccttt catgtcagaa gttcctctac
    23821 catatatctt tccatcaact atttttcctt caaaaggagg aacactccat ttacttgcat
    23881 ctggaactgg aactgtatct atatgtccat caaataatat tttcttacct ggcttgttac
    23941 cttttataca tcctactata tttccatatc tatctcttga ccaactatca aaacctaatt
    24001 tttcaaaaga ctcttctatt gcttttacaa caccttcttc atttccagaa gaactaggat
    24061 tttgaattaa tttttggcat atttcagtta cttcttgttt tctttgttcg tttaacattt
    24121 cattatcccc ctagattttt tataatgtat gtattttata tacttatata ttttctaaat
    24181 tttagaactt atatatcttc taaatatgta aaccaatatc taataattgc attttagtaa
    24241 ttccttatat acttggatat tctccatccc aaactatact tctatatttg tcagggtcag
    24301 tatctccttc tgtgcttatt aaaagtattc ttgaattttc atctaatttt aaatcttttc
    24361 ttaaatctgc taaatcttct ctttccatag ctgctactaa aagaccagtt gtaactgctc
    24421 cagattctcc agaaattacc ttttcatcac catttaaagg attacctaat gttctcatac
    24481 ccttagcaga aacccagtct ggtgctgaaa caaatgctgc tgcatgattt tttaatactt
    24541 caaatcctat agtatttggc tctccacaag caagccctgc cattatagtt ggcatatctc
    24601 ctccaacaaa tcttggtttt ccatctccag cttctgctga tttatagtaa caatcagctt
    24661 catcagcctc tactactact gttattgggc attcatcata tattgaagca acataccctt
    24721 gaactgcacc agcaagtgaa ccaactcctg cttgaacaaa tacgtgtgtt ggtctatcta
    24781 ctccatattc ttttaattgc tctatagctt cttgagccat agttccatat ccttgcatta
    24841 tccacgctgg tatttcttca tatccgtccc atgctgtatc ttgaaccatt actccatggt
    24901 catcagcttc tgcataatca ttagctaatc ttactgcatc atcatagttt aagtctgtta
    24961 tactagcatc tgcaccttct cctttaattt tatttaatct aaattcagaa gaaccttttg
    25021 gcattaatac aacagatttt tgacctaatt tattagctgt ccaagcaact cctctaccgt
    25081 gatttccatc tgtagctgta aagaaagtta tttctcctaa tttttctttt atttcttttg
    25141 aagttaattt gtcataccct aactcagata tatctgtatc taatctttga gctaagtatc
    25201 tacccataga ataagaacca cctaatactt taaatgcatt taatccaaat ctataagatt
    25261 catcttttac atatactcct gcaacaccta atttttttgc taaaccttct aggtttgcta
    25321 atggagtttc tttatattga ggaaagcttt tgtgaaaatt tctaacctta gttatttctt
    25381 cttcatttaa aaatttgata caattttcct tatcgccctt tggcaaatta tttactttcc
    25441 atttaatttc ttttaacatc taaaatacct ccaaattatt gttaaatttt tatactttaa
    25501 tatataagca attaacatgc caacactaaa tatatactag atatttttct atgactcttt
    25561 agtatagaaa ttgcaatgct tttattattt tttcttttct atctttagtt catacaatgt
    25621 atgtagaatt taataactaa aaaacctttt ctatcttctc actttttaat tctcattttt
    25681 aaaatttaaa aataaatctc aaaacacttt gtttctatat tttttaatat aaaatctata
    25741 aaatctaaat taaaacataa aatagtgatg caataatcta ttacatcact atttgtatat
    25801 attcaataat ataataaatc tttagtggtc tctaagaggt gatttttcat cttttttaac
    25861 atctaattct tcttttacga cattccattt ttcaagacca aacttagaaa ccataactgc
    25921 ctctgctgca ccttttccaa gtctttttac tgtgtccata cctgtctcat cctcttgggc
    25981 accttttgct tttccatctt tactccatat tgtaccacct atatagcatc cacctaaacc
    26041 tccagacact aacatttcat gcattaggaa gaaatttatt ataggaagtt ttgtcaattc
    26101 ttggccacca tatctagttc caccagtagt tatagctgca ccaaccttat tttgaagttt
    26161 tcctggatga actaaataca ttggacgaag tctattaaat actgctgtaa gttgagcagt
    26221 tatattcata tcataaactg gagaacctac tataattcca tctgcctcca atattttttg
    26281 ctctaattct tggatatcat cttttataat acacatagtt tcttttctta tacatgcatc
    26341 acaatgtaca caaggactta tttttttccc tctaactgac caatactcag tttctatacc
    26401 aggtatagtt tctgcttctt tcaaagcttc taacactgca tattctgttg ctcctttacg
    26461 tggacttcca caaataccta atatctttgc cataataata tctcctcacc aaataaatct
    26521 atttttatta tctatttaca aatacaataa attgttattt ctgctttaat ttatactatt
    26581 ttaattttat tggtaatgaa tgtatctcta catcagttgc attatatact gcatttgcaa
    26641 cagctggcgc aactggtaca acggcacatt ctccaatact cttaccacca aaaggcccag
    26701 ctttttcata accatctaca aatgcaactt gacattttgg catatctaca gttctaaata
    26761 atttatatgt tttaaaatca gtagctttag gtctaccttg ttcatcaaat gccaattctt
    26821 cactcaatgc gtatcctaga cccatatgaa tcccaccttc taattgtcct tctaaattta
    26881 gaggatttat aactctacca acatcatgta cagctacaaa atcaactact tttatatcct
    26941 tagtttcttt atctactaaa acttcagcaa aatgtacacc ataagaagta cgtccagctg
    27001 gtgaagaata atcttcaaca acagttaact ctcttaatga tttactttga ctatatactg
    27061 cgacatcaga aagtgatgct tttacatttt catcaagttt actaattaca catccattgt
    27121 ctagatataa atcttctttt gatgtttcaa gtaatttttc tgcttcttct aatataagat
    27181 ttttcaattt ctctgctgtc tttttagctc ctccaccttc tacaaatacc cctctacttg
    27241 catagtcacc aaggttgaat gtacatgcat ccgtatcagt ttcaaatgta tcaactttat
    27301 caggtgttat tcctaaaact tcagctacca tcattgtttg catagttaca acaccattac
    27361 ccatatcatg agctcctgtt agcagtgtca acgtaccatc ttcatttaat ttaagagtca
    27421 atgtaacaac atctctatgt gcaccaaaaa ctccattacc atgtgcacct attgccatac
    27481 ctatacctct taaatatttt ccttcttctt ttggaagttt tttcttttca tcccacttaa
    27541 acatcttctt accttgctct atacaatcca atactctagg atttccaaga gaaccgtgga
    27601 agattatatc gacatcatct ggctctactg catttttatt ttgaaaatcg actaaatcca
    27661 tacctatttc ctttgctatt ttcgcaaatt gagcttgttg agccataaat atttgaggtg
    27721 acccatagcc tctcatagct cctgctattg gtgtatttgt atatacaggc atcccagtaa
    27781 actttatatt tggtatttta taaactttaa atactttatg actaagtgct cctataacat
    27841 ttaaagcact tgatgcatat gctcctgtat ttgtatatat ttttatgtct tgtgctatta
    27901 cttcaccatc tttatttaca ccagttttta attttacaaa agacccatga cgagttcttg
    27961 ttgatatcat agattccttt cttgtaagaa ccattttaac tggtcttctt gtcatttttg
    28021 ataatgcggc tgctactggt tcaattgtaa gttctaattt tccaccaaat gagcctccaa
    28081 tagcaggtct tataactctt actttattta atgacatccc aaaaatttga gatagtatta
    28141 ttctaaatcc aaatgtattt tggcaaggtg tatgtacagt taatttatca ttataatcat
    28201 agtgtgcaat tacactatga gtctctattg cactatgatg tattgctgga gtagagtatt
    28261 catcttcaaa tatatagtca cattccttga agcctttttc tacatctccc ccatttatgt
    28321 tgttttgaga aactatattt gaatctccat gtatgcagat agcatcttct tttattgcat
    28381 cttgtatagt aaatacagct ggcaattctt catattcaac ttttataagt tttacagctt
    28441 tctctgctat ttctggagtc tctgcagcta ctgctgcaac acggtcacca acaaatctaa
    28501 ctgtatctga aaatataact tcattttcag gtattttgtg ctcataaaat cttaatgaac
    28561 cattgtattt tctttgtgat gtattgagat aagtagctat agctctaaca cctactactt
    28621 tctcagcttc acttgtatct atacttttta tttttgcatg tgctacaggg cttaaaagca
    28681 tcttagcgta aagtacattt tgtggtttca tatcagccac gtatttcatt tgaccagtaa
    28741 cttttaaagc tgcatctttt agagggtatg attttcctat taccttttcc ataattatct
    28801 accccctaat ctagctgcag ataattttac agcttctata atctttacat atcctgtgca
    28861 tctacagaga ttttctttaa aagcttctct aatttcatct tcattaggag atgcatttct
    28921 atttaaaaga gcttgtgttg ttataatcat accaggagta caatatccac attgtacagc
    28981 tccaacttct ataaaagctt cttgtattgg atgaagattt tctccattag caaaactttc
    29041 tatagtgtat ataactttac cttcgcagtt ttttgcaaga agtttacaag atttcatgtc
    29101 aactccatct atcaaaactt tacatgctcc acaactgcca ctattacaac cttgtttcgc
    29161 tccagttaga tttaattttt cacgaagtac atgcaaaaga gtttcattct tttcaacttc
    29221 tatttcatac atgtaatcat taatatttaa ttttattttt tccattttct cctcctacag
    29281 ataaactaat gttgtaatag aatattatta caatcttatt ttaatattag tataagctat
    29341 tccacttatg tccttccatt ctattagtta cattagctct cttacataat tcttctgctg
    29401 catgttgtgc attaagcaac acttgttctt cactttcaat tgtagttact tttccatttt
    29461 caagtattac atttccatca actaaaacac tctctacatt gtgcatacta gctgagtata
    29521 ccaaagttga tacaggattg tgaagaggta ttgattttgg agaaagcatt gagttaaata
    29581 ttactaggtc agcttttttc ccaatctcca aagaacctat ttcatcttcc attctaagag
    29641 ttcttgctcc ctcaattgta gccatttcaa gaactttctc tgcagaaatt gccagagggt
    29701 cacaattatt tactttgtgt tgtaaagctg ttagtttcat aagctctacc atatcttgtg
    29761 cgttattact tgctgcaccg tcaagaccta aactcacatt tatacctttt tttaacattt
    29821 ctggcacagg tgcaacacca gaagcaagat acatattact tgctacatta tgagaaactt
    29881 ttatgtcata ctttttaagc atttccatgt cttcatcagt tatacataca caatgtactg
    29941 ctacaacttc tggacctact ataccccatt tttcaagtaa ttttatatct atttctccat
    30001 gtatatcctt tgttgctgtt cttgcaaatt ctgtttcaga tatatgaact gtaaaatatg
    30061 aatcatattc tttaactata ttccaaagca tcttacccat ttcttcagat atagcccaca
    30121 ttgaagaagg agctacacag atttttattc ttccattttc tgaattatga tatttttcga
    30181 atacccttct caaatctttt tcaaccgttt ccacatcttc tataagctct ttgtgaatac
    30241 ctaaatctat acaacctcta cctacaaccc ctcttatgcc taaatcttta tatgccttta
    30301 ctattccatc tgtaagtcct ggtctattgt gagtatgcat ataatcaacc attgtagtta
    30361 taccactttt taaaccttcc atacatccaa gcattgcagc atcataagta tcttgttctg
    30421 ttaagaattt tgctgatgga aacatcattg tatttaacca ctcatgaagt gccatatcat
    30481 cacctaaacc ttttaataac acttggaaca ggtgattatg agtatttata aagccaggga
    30541 atattacttt tccattagca tctataactt ttttagcatc aagatactta ggctcgatat
    30601 caactgtatt tcctatgtcc aagattctgt caccttgaat agctattgct ccatcaaata
    30661 taacatctct gtctttatta actgtaacaa ttattgcatt ttttattagt atatcaatca
    30721 tcttaaatcc ccctttgaat actttcatta caacatttta ccatatggtt ttctcatatt
    30781 atatctaata catttatcca atattttctt caagatttga agtaacgttt tcagcacttt
    30841 tacgtgactt taatttaaat aatgtttgaa gtaatatagc tattattgct ccagaaacta
    30901 tacttgaccc tccaaggaca gttccaattg tttctgggaa ttggtctaaa acttgtggag
    30961 cagttgtaag acccatactt gttgctatag atacacctgc tataagattg ttttcttcag
    31021 tgaatccatc catactcata atagagaaac cagacattgc tattgatgag aaaactacta
    31081 aagttgctcc accaacaaca caagatggta tagttgtcat tattgcaccc aatgctggag
    31141 atatccctgc tagtaataat acaagtgccc ctagtgctat tacaaatcta cttgtaactt
    31201 tgttcataga tacaattgct gtattttggc taaatactcc agttggaaga gctgcaaata
    31261 gtgatgaaat tatagaagtt atagaatttc ctaatacaac tgatgctaat tcttcgtcag
    31321 ttacctctct atccattgct cctactgtag ctattgtaca ggcacccatc atatcagcta
    31381 tacctattat gtaaataata gtaaacatta ctattaactc tggtctaaat tctaatccaa
    31441 aagctgctgg tgttggtaaa gatactatag ctgctccttg aacggctgag aaatcaacca
    31501 atcctaaaac taaagatata gcataaccta ctaatattcc tattaatatt gaagaatttt
    31561 ttactaaacc tttaccgtat ttatttatca ttattattac aaaagcaact ataactccta
    31621 ctgtgaagtt tattgggctt ccaaatgttt gtgtgccttc tcctccagct aaattcttta
    31681 tagctgttgc gaatagtcca agtcccatac atgctattat agttccagaa actattggag
    31741 tgaatatatg tctaattttc ttaactccaa atcctacaaa gaatacgatt accccagcag
    31801 caatctgtgc tccaaataga gctgctaaac catctttagc tgctactgaa agacaagctc
    31861 ctaaaaatac ataactcatt cccatcatta caggtaatct tgaacctaac ttaaatcctt
    31921 taaataaagg tattggatat aactgtaaaa acgttgctaa acctgctgct aacatagaac
    31981 cctgaatcaa cattgttgct tgcccctggt taagtcctac cacgtttgct attaatatcg
    32041 caggtaccat atttcctact atcattgcta acagatgttg taaggccaaa ggtattgatt
    32101 cctttagtgg tggtatccca tcgacatcat attttgaagt attacgtgtt ttcataaaat
    32161 aaatcctccc atacataaat atcttgacta aatattttta taattatttt ctataaatat
    32221 ttttatgacc atgaatttat tgctcaaccg ataaacacag ctaaactgag ctatttttat
    32281 aaaaaattaa caaatttcta aatattgcct ccccgatttt caacttaaat gaacattaat
    32341 tgcctggtat atatttattt gttaaatttt ttattaaaat gaatagctat caaaaataat
    32401 ctaacaatct catactaaat aatttaaaca attcttttaa attattatat cttaattagt
    32461 ctcttccata acagctcttt ctttagcctc atcctctaga cttttatttg gtattattag
    32521 atttaaaacg aatgcaacca atgttgcaat tactattgga gattctccaa atactaactt
    32581 tacaaatgaa ggaaatgcct cttgggctgc tgggactgat gttattccca tgcctaaggc
    32641 aattgccaaa ccaacaatgg taatatttct tgatgacaac tcttctgtaa taattaactt
    32701 tatacctgtc attgttatta tactaaatat agatattgta gctcctccta aaacagaata
    32761 tggtatagta gtcattaatg caccaaattt aggcacaaac cccgacaata acataaatat
    32821 accagctatt ccaagcacaa atctacttat tactttgttc atagctacca tccccacgtt
    32881 ttggctatat gatgatggtg gtaaacctcc aaacaaagct cctatcatag tacaaattcc
    32941 acttcctatt actccacttg ataattcctt atctgtgata ttcctatcca tgcctcccat
    33001 tgtagtagct gataagtctc caattgcttg aacagcattg attatactta caattactac
    33061 tgagattatt acaggcatat caaattccat cccaaattca agcggtttag gtatcgcaaa
    33121 ccaagttgcc tctctaatag ggtcaaaatt tattataccc agaactaaag atacacaata
    33181 tccaactata attcccaaaa atattgctgc caattttgca tatccttttg caaattgact
    33241 aagacctata actaccacta atgttatagc cgctactgcc cagttttgca tagaggcata
    33301 agtaggacta tttacaccac ctgccatata atttattgct ataggataca aagataatcc
    33361 aattgtaaaa accactgttc ctgcaactat attcggaaaa aattttctta tcttttttat
    33421 gaatatccct attaatactg tagccactcc ccctattaat tgtgcaccca aaatgcttgc
    33481 taatccataa tttcctccga ctgctacaag tgttggtaca taagtaaaac caactccaaa
    33541 aattataggc aatcttgaac caatatttcc tattggatat agttgtataa gtgttgatat
    33601 accagctatt attaatgcat attgcactaa aagtgttatt tgtgtagggc taacacccac
    33661 agctcctcct acgactatag gtactgtaac agttccaact atcattgcta gtatatgttg
    33721 cattgatagt ggcaaacact ttaaaattgg tggccttcca tcaatatcaa acatagaaac
    33781 attcttttga tatttactca aggttatcac tcccaactat tttttaatga cagttattat
    33841 tatctcacac aacatccttt ctttttttat tttgtcatct caacttaata tgaagcaatt
    33901 ataatgccaa ttttttaaca taattgtttt acatatataa tttttattat atttgttagt
    33961 atttgataat ttattaaagc atttattttt ttaaattctt ttaaattttt tttatttttg
    34021 gataataaaa tgctattaca caaaaaaaca cttagaaaat agttttccaa gtgtttttta
    34081 tcaattttat aatttcaaat tttagaattg agaataaaaa gcctaattat tatacatcta
    34141 tttttctgta caatgtagct agtgatattc caagtttttt ggcagccagt tttttagact
    34201 tagtatcatt tccgtaaaac tttaacactt tctttatata ggctctttca aactcttcaa
    34261 gtgtaagtat gtcttgttcc atacttatct catagtcact ttcctcaagt aactttatat
    34321 ttatattatt taacttaaaa tattcaagta tctttctatt tattattcct ttatgtatta
    34381 ttccatcttc ctcaagaagg tttaatgcca gttctatagt attttccaac tctctaatat
    34441 ttcctggcca aggatactta agcaacattt gttccacatc tggctctata tggtacacgt
    34501 ttttcttcat ctttctcgaa tatttgtcta taaaattgtt tattaatatt tgtatatcgt
    34561 ctcctctttc tctaagtgga ggcacttcta aaggtattac attcaatcta tagtataagt
    34621 cttctctaaa tttattttcc ttaaccaact caaataaatc tctattagta gctgatatga
    34681 ttctaacatc tatatcaatt agttcatttg aacctattct cgtaaacttc ttttcctgta
    34741 ataccctcaa taactttgat tgtagttgaa ttggcatatc tcctatctca tctaaaaata
    34801 caacccctcc attggccaat tcaaacttac caattttacc ttttgaatct gctccactaa
    34861 aagctccttt tgtatatcca aaaagttcac tttctagtaa aggttctggt atagcagcac
    34921 agtttatagc aacgaatgtt ttattccctc tgtttcctgc gagatgaatg gctcttgcta
    34981 ttaattcttt tccagtgcca ctttctccag ttatagctac agtagaatca ctatttccaa
    35041 ttttacaaat tctattctta agagcacgca ttacatcaga ctctccaatt atggagtcta
    35101 ctgttgttgt tccccaaata ttatatactt ccattccacc atacattact gaatcactgt
    35161 gtttgtccat aaaatatcaa ctccaaataa gtattctata taataatcat tcacattatc
    35221 tatttaatta tatcataaca gaaaagctta gttataattt aataatatta ttttaaaaca
    35281 aaacttaata aaaagtatat ctacttagtt ttaatttgat agatatactt tcttcatttt
    35341 acaaaaatgc tctattaaat aagcaattac aatgccatat tttatatgga aataattttt
    35401 aaaattttta atttaagttc ttattaaatt ttttatacta ctcgtaattt ttatacctat
    35461 ataaaattac ttttataaat tttaaaattc ttatttttaa aatttataat taaaaattat
    35521 cttttttaaa tcattttttg tgttttttat atcatctaac ctcacagttt ttgcttctat
    35581 aaacttaccc ttaaatgatt ctgataattt ccaggaacta taattcttat ctttttgaat
    35641 acaaggatat aataatatac atctttttgc attttcatat gctgttatat atgcatacat
    35701 ctggtatata tcacttgacc tataaaaaac atttgaatct acttcaatag ctttccattt
    35761 agtgtcaatt ataatttcat attcattttt taagtcatat aaaactatat ccggtcttaa
    35821 attaaagttt ttcttacctg tttgttcatt tttcaaaaga aatttactct tatcttgtat
    35881 atatgtttct ctaaatgaat tgtcccatat acttttgatt aaaattccta tatattcttc
    35941 atacaaagta tttatttcaa ataatataga aaatgcctct tgattatttt gactattatc
    36001 catagacaaa tttaaaagta taagtctagc tagtaaataa caatctttaa atctatcatt
    36061 gtttttataa aatttataat ccaatagttt ttttctatct atataaatta aatctacatt
    36121 ttgaaaatag cttaaaattt ttttaatctt gccttgaatt gaattgtcat ttattctaca
    36181 taaaatagat atacatgctt ttttaagaac ttgattcaag aaattatttt cactatactc
    36241 atcatattca catcttattt tcattggaga aatgcctttt tcttttgcat atgtacttaa
    36301 taatatttta cccctcataa catttaagtt ctctatttta tttatatatt caaaataaat
    36361 accttttttc atctgtgttt gcatactctc aatgaaatac ataacaaaaa aatttaagag
    36421 attataattt ttcaaactca atcttatttt ttcattcatt gtaattggaa ttttattaca
    36481 tatagaaagc atctgtaata gtatctctct atcttttaca agattatcac ttaatgacaa
    36541 tttaggaagt atttcaagta ttacattttc aaaacatatg atgcctacat agtttataaa
    36601 tctaagtttt ttgtatttaa tatctattat attacttttt aatacatcat tattgttctc
    36661 tagatattta agcaattttt catattcaat ttctgtaagc tcattttcac cattacctac
    36721 ccttatccat tcataggttt ccttaacata tatattttta ctcatatata ttttttagct
    36781 cctcactaga tatgttttgt tttatacaat agttaacttt actctccatt attgaggcat
    36841 tattattttt aaataactca gaagctataa gtttttcttt ataaacaatg tatttatctt
    36901 tttcatttct tccaattcct cctaaaatca aacctacttt ttctgaatca taataaaaat
    36961 actcttgaag aagtggtatt attttacttc taaatactac tactatatca ttaatatttt
    37021 ctacagcaag tagataagct tgtccaataa catgatctct atcatataaa aactctatcc
    37081 ttttattgat tgtatatagc atttttctaa tatctatacc atctacaata gacaataaat
    37141 cataatctgg cataatttct tcaaaattaa accttcttct taaagctata tctaaaagtg
    37201 ctattgattt atctgatgtg ttcatagttc caactatata caaatttgga ggtagagaaa
    37261 atttttcctt tgaatatggt agtttgacaa tagtttgatt tgatttagta agtcttttat
    37321 catcttccaa taatgttatt agctcaccaa atattttaga tacattccct ctattaattt
    37381 catctattat taaaacatag ttttctgatt cttcaaaatt aaaactctca ctatattcta
    37441 tattttctaa tactaatttc tttttcctgt cttttatagt ttctaaagtc aagctatctt
    37501 tttccaactc aaagctcatc tttttttcaa atttcaatgc attataacat gcttctatag
    37561 atatatcctt taatatccca tcttcttgct taaaattgcc ttcaccatca gacttaagac
    37621 cctctataaa ttcctcatat ccatatgatt gatgaaatgt acaaaattct acattgtttt
    37681 tataatctaa gtaacctgta tagtatttgt ttcttagact ggtttcactt actagattgt
    37741 aaaccatctg ttttgtattg tatgttttac cagttcctgg tggtccataa agtatagtat
    37801 ttaatggcat tttattagta aatcttttta catacttttc aactatacta ttattttcaa
    37861 atataaccca tgcatttccg tctatattct ccttttcata ctctatccat ctaacaggaa
    37921 aaaaatatcc accttccaaa gcacttactt tctctttatc gaacccttcc ataacttgac
    37981 atacgccaaa tagactcttc attgtatggt cattttcaca aattactttc tcgctattat
    38041 acaataaaat ataatcatct gtctttatat tttttaggct ttctaattgt tctagattaa
    38101 tgggctgaat aaataattct tcatcatcta cacacttatc tacattttta taataatagt
    38161 tttttaaata ccatttatta ttttcacttt cttctattct ttttctcaat aatttcttat
    38221 cttgtgactt aataatttct aaatatgagc taatatcatt attatttaat ttataaaatt
    38281 cacttgtata tactttacaa tttgaaactg tatcaaaatt atgcatccat tttactggta
    38341 gtgtatgccc taaaatatga cttaattcat atccattttc aaaatcttct tcaactatgc
    38401 caatagacac attacattta actttttctt ctatattttg atatgcttta tataaaaaat
    38461 aatctccttt tttaatcgac ataaactttt ttataaaatc tttatcatta caattctcat
    38521 taatatactt ttctgatttt ttccccatac tgaatacttt ttttaaattt atttttatgt
    38581 caaatccaag tgcaattatg ctttcttctc taaaaatctg tggtgtgtct gtttcctgat
    38641 aaaaaaattc ttccattaac caatactctg tacctcttat attttcagac atatacactc
    38701 tccttaatat ctaaaatata ctaattatac aataagccta ctctaatatt tccatttaaa
    38761 ttttccttta tatataaaga aaatattact tcatagcttt cttctacctt gctctgaata
    38821 ttacttatta aatcattcaa ttccattata gaaaattctg gacttccttc aacaaataca
    38881 attcctttct tacttataaa ttcctcacca atatattcca tcctgtcaaa taaaatgtca
    38941 gctatctcgc tatatgactt tgtatcttca aactcttcaa aagaatactt aattccttta
    39001 tctcctacaa tagcttcttt taaatcagta atatctatat ttatcatgca agaatcagaa
    39061 atagactcta ccatgatatt cattaaatca acaaatttaa atatactatc attattgatt
    39121 ttaaactctc tcccaagctc taaatcttct ttattttctt tctctgaaca atccattcct
    39181 atagatagaa ctcttctttc gtttgacata tatgaaacag cttttataat atctctaata
    39241 tgtttatctt cagatgaata tatcaaaaat aatatatcta caccatctaa aagacttcta
    39301 acatattctt tttcaatctc ttgatttatg tttatttttt ctatatccat atttgctttt
    39361 attttttctt ctacttcatt tattatatta ataccttcag ctccaatacc aattatttta
    39421 gcattcttat taaaattttc cattataacg tatatctcct taataattat ttaatttcaa
    39481 catttctaaa tattatacca tattttcttc ataaaaatat cttaactcat tggccttatc
    39541 ataaagtagc ttattcaaaa attttggctc tataacctta gcattatttc caataaaaaa
    39601 taaaatcgaa gcataacaat ctatatcttc aacctttatg aatgtactaa ttattccact
    39661 accatcttca tttagctcca tatctaaatt ccaagaactg tcctttattt tagaaacacc
    39721 ttctttagtt aataatacat ttagataaat aatttcacca aattttttag tagttgaact
    39781 atttccatat aaattgttat atacttcatg taaccattct tccaagttta tatgtatttt
    39841 tttactttct cctgttcttt ttatatcaat tatattatct atatgaacta atattatttt
    39901 atcactttta caatcatatg ctggtgaaaa ccatgctccc ttatttaaat atatacctat
    39961 agggcatacg tttttttcca aaatctgatt accacactta tacttaatat ttaaaattag
    40021 agattctgaa gaagctctaa aaaactcagt tacattacta ctcttaaaat ctccatcatt
    40081 agtatcatta gctacaaagc caatgtatct tttaatattt tctataccta cttttatact
    40141 gcttttacgt tcataactta cttttctcat tatagaatta atttctattt ccattaactt
    40201 ataattataa atctgaagtg acttaagtgc aaatagtata atcataactt ctttttctgt
    40261 aaatataaca ggaggtatat agctattatt tagcacccta taacctccat ttctaccttg
    40321 ttctgcttga attggaagtc ccattttatt taattctttt aaatatcgtt gtattgtttt
    40381 agctgaaaga ttaaattcct ctgacaactc ttttattgta aacttttgct tatcattaat
    40441 atatatccaa acatcagtca atctttttac cttcgacaaa taaacacctc ttttcactaa
    40501 taatactctc aattaattaa attactatac actatttaaa atttaatatt aatgacattt
    40561 ttatattttt tcattaaaaa gcagaaaaat ggtactccta caattgtcac tactacaaat
    40621 tctccaaaac ctacttgtat catagataga attaatggaa gcccaaagaa tacatttaac
    40681 attagaccaa ccacaatcga atttataaca gttggccata aagaagctat aactaaagta
    40741 cttttattct gtttacctaa ctttctagta atataaatca tacttgcact tataaatgtg
    40801 gctaatgttc caaaaattat atcaggtaca ccatatggtc ctattacatt tgctaaaaaa
    40861 caacctaatg taagacctac tatatatcct ttatctaaaa atgccaaaag catcataatc
    40921 tctgctaccc taaattgtat tggtccataa cttataaatc ccaatgataa tgttaaaact
    40981 gcatagattg ctgtaattgc tgcagttagt gctatattaa tactattttt tctcatatct
    41041 gtctcctagt aaaagtttta tttctaaaaa aattaataac ataactttat tttatacaaa
    41101 atctataaac ttaaacagta attttataaa aacaaattat tttatcgaac tatttttcca
    41161 attcatttta cattatacaa tataatacat acaaattcaa ttttatatat atagaatata
    41221 tgatattaaa attatataca aactaaagat aagttttcta ttgttaatta aaaacagcaa
    41281 aaaagagcct taaaattagg ctctaataat ttattttaaa atcagtgaac tctactacca
    41341 tcttttaatt tagataatat catccaagta cctatacaat caatttccag ttgtttctct
    41401 atttcatcat ataacatttc ttgatatgat gtatttaaaa caacattttc aaccaattta
    41461 gaaatttcct cttctgcaaa atcaatttct atttgatttt gtttttcttt aaaaaatacc
    41521 cttacttttc tctgacttat tgaacgaccc tcaaagctga ctaaacattc taaaatgttc
    41581 ttatctcctc taaaattatt tactgctctc atattattta gattaccagc caaaacatca
    41641 tccccttatt taattttgta ttttataagt aaaattcata atattataat aactacttat
    41701 taaatatctt tcaacaggta tgacataact ggttgtttaa catgtaaaac tagtctaaat
    41761 tttcataaat aattatttat tcatttccat aaaaactttt tcaggtgtaa tagggagtgt
    41821 atttattctt acaccaattc cattaaacac agcttcttgt attgctggta aaggtgtatt
    41881 tataacaact tctccaacag atttagcacc aaatggtcca gttggttcat aagtttcaac
    41941 aaaatctact ttaacatttc caatatcaca tctagctgga atcttgtatt gcataaatgt
    42001 atttgtgtcc attcttcctt tttctgtgta tctaacttct tcaaataatg ccattccaat
    42061 cccttgaaca attccacctt caacttgtat cttagctaga tttttattta taaccgttcc
    42121 acaatctact acagctacat aatttactaa atcaactttt ccagtttctg tgtcaatttc
    42181 agtttctgca aaacctgcta taaaaggagg aggagatact gggctaccat gagaagcaag
    42241 acctattaat tgattagtat ctggaccaat tgtagaatca actgctatat cgaataataa
    42301 agtgctacct tttttactag ttaattttat accatcaaat tttacttcat ccttctcaac
    42361 acctagttta gttgctccag cagaaattat tttttctctt aagtcttgag ctgccttaac
    42421 tactgccata cctgttacat aagtagtact tgaagcatat gaacctgggt catatggaac
    42481 taagtcagta tcagctgata taactgttat attttcaatg cttgtatcaa gaacctcagc
    42541 agccatttga gctaaaatcg tatcacttcc tgtacccata tcagtagaac ctatcataag
    42601 agtataatct ccacagtcat tcaattttat ttcagctgaa gacttatcaa gaccttgtat
    42661 accagaacct tgcatagtaa ttgccatacc cacacttcta atttttccat tatcaagatg
    42721 tttacaagga tatttttcat tccatccaat aagttctttg cctttattta tacattttat
    42781 taaatcgaca ctatttaaag ttttaccata tgcaaatgta gtttcacctt ctgttaccac
    42841 attttttaac cttaaatctg ttgggtccat ttttaattta ttagcaagca tatttatagt
    42901 tgattcaaca gcaaaacatc cttgtgatgc tccataccct ctaagtgctc ctgctggcat
    42961 cttattagta tataccacat ctgcaataaa tcttgttgct tcaactttat tatacattgg
    43021 taaagttttt tctccaacca aaccaatagt tgtagaagca tgctctccat atgctcctgt
    43081 atcagaaagt gcttttatat ctattgcctt tattatgcca tcatttgtag cacctagtct
    43141 aacttttaat ctcattgcat gtctacttgt tgaacaatta aaagtttctt ttctatcata
    43201 aattatttta gctggtttcc ctgtttttaa agtaacaatt gcagaaaaaa tctcaacaca
    43261 tgcagtttgt ttaccaccaa atccgccacc aattctaggt tttataaccc taattttgct
    43321 agctggtatt tctagtgcac gagataaatg tctttttaca tgaaatggta tttgagttga
    43381 acttactaca accaatcttc ccatatggtc taaataattg tatgccctat acgtctccat
    43441 cattgcatgt gcttgagctt gagtataata agtttcttca atcactacat cacaattact
    43501 taatactttt tctacatcac cttttgtata atcatgatgg gatactatat ttttttctct
    43561 ttgcatacct atatcaaagt tacaatgtct atcttcatca tgtaccatag ttttatttcc
    43621 tattgcctct tcaaaatcca aaacaggtgt aagtacttca tactttactt tgataagatt
    43681 cattgcttta attgcagttt tttcatctat agctgccact atagctactt cgtcacctac
    43741 atatcttaca acatcttcaa gaattaatct atcatatgga gatggctctg gatatgtttg
    43801 accagcaagt gtaaatcgag attttggtac atctttatat gttaaaacac attcaacacc
    43861 atcaaccatt tctgcctttg atgtatctat atcttttatt tttgcataag cgtgaggact
    43921 tctaagtatc tttaccacca aagcatcttt tgctgataaa tcatctgtat atacaggctt
    43981 tcctgttgtg atactcattc catctatttt cttgattcct tttccaacta tattcatgtt
    44041 ctattttacc tccagataag ttttgatagc tcttaactgt cccatatacc ctgtacatct
    44101 acatagattt cctgtaagat aatgctttat ttcatcatct gtaggatttt caagctcatc
    44161 cttcattgca agtacagtaa gtataaagcc aggagaacag aaaccacatt gctcagctcc
    44221 ttcttttacc aaaacttcac taaattcttt aacttcattt tctaaacctt caattgtagt
    44281 tatttcttta tctaaagctc tcaatgtcag tgttgcacag gataatgtag gtttcttgtc
    44341 aattaaaact gtacataaac cacaacagcc tgtgtcacaa cctcttttca cacttaaatt
    44401 accaactttt cttaaagtat caaccagata ttcttctggt tctatatcaa cacttttttt
    44461 cttcccattt atattaatct ttactaacat taaataacct ccattatagc tctttttaaa
    44521 agtactttac tcatagcttt tctatactcc ctagatgctc tcatgttaga accaaaagtt
    44581 agttcttctg atgctatttc tactgcttta tctatattaa tttcattgat ttcattgtta
    44641 gatagaaatt cactagcttg ttttgcaatc gtagctttct gcggtcttgc tcctacacat
    44701 aacttaaatt gttccatatg ttttgataca gatacattta gaattggata atcactcttt
    44761 gcatttctaa gtgatttata agaagcattc ttatttgtct tctttatgta tatcttaata
    44821 agtaaatctt tctcataatc tctatttaga aactcttcaa gactaattct cccaatatta
    44881 tataattcta cttctgtatc taatgaaagt aatgctacta tcaagtcaga aaaaccatat
    44941 ttagaaaata ctgttgcacc aactgttact acatttctaa actgaactcc tattatattt
    45001 ttaactgaat cttctattat tcttccaaaa ttatttttta ttatggaact tgtttctaat
    45061 gttctaaaag tagtcataga accaatctca acgtaatctt catactcttt tatataatct
    45121 aaatttaatt tagataattc tattcctgtt cctattcttt ttttccccat tcttaaaaaa
    45181 gcacttccac caattacttg gttagttttt cttttattta aaattgagta cgcttcttct
    45241 actgtatctg gctgtacaat atccataacc gtaaacataa atttcctccc ttatttgcta
    45301 ttcttatttt aaatacaact aattatatca tagcttcaac aaattttgat aataaatatg
    45361 tctaatatgt aaattctgta aattacttat acataaaaaa atgactattt caataatcat
    45421 cattagacaa tattaaaata gccattaaca ggtactattt taaagcaaaa ctttaaaaag
    45481 ttgatacttt ttcacttata tttatcactt cttcttctaa taatccaagt tttttagcta
    45541 ctaattttgt agtacttcct tgtattacta atgtaattag tatagtcata aatactacag
    45601 atgaaatcac ttcgtatcca ggaactttca ttgctgaaat aataccacaa agtgctgctg
    45661 gtattacgcc tgtttccctt acccacatca taaataatat ttcactttta ctccattttg
    45721 cttccctgtc tacaagtgta caaactaaaa cgcaaagtgg tcttgctata aacattaata
    45781 ctaatactgt aattacagat ggcataaaat atttacttaa ctgagccaaa ttaacttggc
    45841 tacccaatat tataaatatt gccatacgac aaatagtacc taaagtttca gcaacataaa
    45901 aatctgcatc ataagatttt tgacttaacc aaattttaaa gtttttcttg ttaccagtta
    45961 ttatacctac aataaagcaa gacatatatc cacttccacc taattttgta gataattcat
    46021 atgcaactac aactgaaata acagatatta ttggtgcaaa atctttaaat attccataag
    46081 gtttatcatt aactaatttc aaaagcagta ttcctgtaat taaaccaact aaaactccga
    46141 caataaccat tgtccccagt tcataaatat tttcacctaa tgaaaattta tttgacaaaa
    46201 ttacagccaa cactgctgat gttagtatag ctcctgttgc atcattaaaa gctgattcac
    46261 ttattacagt ttgttttacc ctatccttta tctttacctg attaaatata ggtacaagag
    46321 tggctgggtc tgttgatgct attatagttc ctgctagtaa agcagtcatt gcacttatcc
    46381 caaaagtaaa tcctattact tgttgcatta taaaagcaga tatcacaact cctaaagtag
    46441 ctaataagaa tacagatatc ttcacatttc tcaatacttt taaacttatt tcttttccac
    46501 ctaaatataa aataaatgca gaaccaaatg taagtattag ttgattttct atttgaaatc
    46561 cacgaatatc tataaatttt aaaaatgatg gtcctattaa aatacctaca agtaaatata
    46621 acactacatc tggaaccttt attatttcac taagcttact acaaattatt ccagttatac
    46681 ttacaatagc aaaaattatc aataaattat tgctggcaat tgtgtgtata gatgcttcca
    46741 tgtccgtctc tcctcccgat ttgcatacat tatgcaatat acttattgtt ttactatata
    46801 attatagcac acaaataaat gttatcaatc atttttttta ggacatgcaa tttagctttc
    46861 atttttgaca attaaataac gcttatataa ttttgctatt ttttgctagt tattaaaagg
    46921 ttgattttgt caagtttata gtatatatat attaatattt tttatatcca tatcttttta
    46981 gatatttttc gactttttcc cccattaaaa taagtttaaa tttaacaata aaacatttca
    47041 ttatatatat tttttaaaat gtaccatttt caacattttc attaacttgg tctattcatt
    47101 tttttcttat ctattctata tccaagcata ttccctatat ttttacttac atgtaattct
    47161 tgagctattt caagtttatt atcattgctt tgttttatct tagaaatctc actttgtttt
    47221 tcattttgtt tatcttgttt catagtttct cctttcaaaa caatatcact ttttctgttt
    47281 attacttatt atttcaaatt tctataattt taatcaaaaa agggaaatat ctcaatataa
    47341 tatagcttat tcaacaccat atttatatat agaatttccc taattatttt attaatttaa
    47401 tttttcaata accttatcta aattagaatt tactttattt tcctttttcc aagaatttaa
    47461 tgtataatgc gttccaaatg taaataaacc tgaaactatt aatataaaat agtatacaaa
    47521 cccactatat aagagtacag agtaccccaa taattctttt ggaattatat tggagaacat
    47581 agtaaaaaat gtaacctcat tagctccaac atttcctggt gttggaattg gtgatatagc
    47641 catatataaa aagacctgta atgtcattat atgtacatat gaaactcctc ttaaatttga
    47701 ggctttatac acacaataaa ctatactgaa atatgcgatt aattgtaaca cagtaagtaa
    47761 tatacttaaa actaagattc ttacattttt aataaatatt tttatagaat aattataatc
    47821 atcaatataa tgatttattc tatcacgttt tgaatctaaa aatttaaatg ttttaaattt
    47881 agataaaaaa ttaatcaaaa cttctgctat catttttact tgttttggac taaatactat
    47941 tagtagtcca cctaacaaca tacttacatt cataatcatt ccaaaagtta tcaagacttt
    48001 cacagaatgt acttgctcca tcagtaatga cttatttagc aaaattaaaa ttccacaaaa
    48061 tacagtaact gtactttgaa atactacagt tttattagta actatagcca ctgatttact
    48121 aaggcttaca tcatattttg taagtgcata tatttgcatt ggttgactcc cagatgcaaa
    48181 tggagtaact aagttatagt aaaatcccat tgtagccatt ttaataccaa taaattttac
    48241 ttttgttttt tgaactgcat ttattatcaa atgagttaca atagattcaa ttatcatata
    48301 tactataatt gtcaatatgc caagaaatat ataagtctta tttactagcc ttataatttt
    48361 aggtatt
//
LOCUS       DAEPKC010000019        44580 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.019, whole genome shotgun sequence.
ACCESSION   DAEPKC010000019 DAEPKC010000000
VERSION     DAEPKC010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 44580)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44580)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44580
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.019"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            194..1066
                     /locus_tag="KR294_001181"
     CDS             194..1066
                     /locus_tag="KR294_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0239269.1"
                     /translation="MEMKIAVSNLSKRFGKKQALDNINLEIDSGMFGLLGRNGAGKTT
                     FMRILATLLSKTEGSIHMCGVPIENTKEIRNMVGYLPQDFSMYPNMTVYKAMDYLAVL
                     SDIPLRKRRKIIAKLLSKVNLTNYQNVKVKSLSGGMNRRLGIAQALIHNPRVLIVDEP
                     TAGLDPEERIRFRNLLCEIANDRIVILSTHIVGDIEATCENVAILNSGKVIYNGSTEA
                     LAKLAEGKVYSIEVDKKDIENIKSRFIVIGMLTHGGKAILRIISDDKPFETAVNCNPT
                     IEDGYMLIMGGDNI"
     gene            1063..2352
                     /locus_tag="KR294_001182"
     CDS             1063..2352
                     /locus_tag="KR294_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0239270.1"
                     /translation="MNLFIKECKNILKSMIYYIFIVVLVFFYISQLGSSVSNDVSKNI
                     PNDGNPLVAPQKVENIEEYYSVHNQYPYGQKESMKTEKVIPNATINLIREYQKNTYTT
                     YPTGVVKYIKLDQNKTKTIEKYIEEITGKSISEINSLWKTDESIKIDYSKVSLERFEE
                     IMQRVDDILGGGSAYAFDKLQRFGVVPVTYDEAMKNYNYTIQKDKVSNGYARIFCDYI
                     GIVLSIFPVFVAVFMSLKDKRSRMREIIYSKQVSSCKIVLSRYFALVFMMILPVLILG
                     MKDLLPLIFFAKDKGISIDNLAFIKYTLWWILPTLMIVTAVGMSITILTDTPVAIIVQ
                     LIWWLYSINSTGLKGDYSTMGLMIRHNSVLNGDIIIQNFNQIMINRIVISLGALVLVL
                     LAIFLYEQKRRGNLDVWAKFSKLFSSNKRKLQIKHFN"
     gene            2282..2926
                     /locus_tag="KR294_001183"
     CDS             2282..2926
                     /locus_tag="KR294_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0239271.1"
                     /translation="MFGQSFQNCLVLIKENFKLSTLTNLICSIILLCMIPLIQGVANL
                     DRISTAICLENYVAIIGIVMLVPVFSLEQSKEIDEIVSSKALSQVIVQLIRILMSIIG
                     IVVLIIGFVNVLIYLGCNFPVVEYIIGSFASAMFIGSLGMFFSNLFNNTIIGYMISIG
                     YLILNMMTKGKYVGKFFIMSMSQGSFDEKYWLILGSVVLIIASLLIKPVKRKIR"
     gene            complement(3193..3656)
                     /locus_tag="KR294_001184"
                     /pseudo
     CDS             complement(3193..3656)
                     /locus_tag="KR294_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861860.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            complement(4656..5483)
                     /locus_tag="KR294_001185"
     CDS             complement(4656..5483)
                     /locus_tag="KR294_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AIM24 family protein"
                     /protein_id="HBH0239272.1"
                     /translation="MDLSKKVKILENASDGKSEFEILEFEKLEGASSPLMAMGLYFAR
                     EAGLKARQIKIKLNNSSIKTEAGALYYYKGNISSETKIGGVGGLFKKGISGALTNESM
                     MKPVYKGTGEVYLEPSFRHYLFMSLDNDSIIVDKGLFYCCSDTIEVKAFTQKNFSSAL
                     LGGEGFFQIELSGTGVIVLECVVPQSEIVEYELKNGEELKVDGNFAIARTSGVNFSVT
                     KSDKSLIGSALNGEGFLNTFTGSGTVWLAPTQVMYEKLSFGAMPTNDNMNNKVSKQK"
     gene            6138..6593
                     /gene="smpB"
                     /locus_tag="KR294_001186"
     CDS             6138..6593
                     /gene="smpB"
                     /locus_tag="KR294_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HBH0239273.1"
                     /translation="MAGKKILATNKRARHEYFIEETYECGIELKGTEVKSIRQGKVNL
                     SDGFASVDNSEVFLKQVHISPYEQGNIFNVDSLRVRKLLLHKHEIRKLIGATTIKGYS
                     LIPLSLYLKNGKVKVEIALAKGKKLYDKRQDMAKKDAQRRIEREMTGKY"
     gene            6751..7100
                     /gene="ssrA"
                     /locus_tag="KR294_001187"
     tmRNA           6751..7100
                     /gene="ssrA"
                     /locus_tag="KR294_001187"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            7215..9242
                     /locus_tag="KR294_001188"
     CDS             7215..9242
                     /locus_tag="KR294_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HBH0239274.1"
                     /translation="MSIDNNFNHVAFLWNIAESLRGTYKEEDYRKVMLPLIVIRRFDC
                     LLDDYDREIIKSVYEEYDFLPEEERDELVIVDLKENHDINLQFYNVSDFTWKKLLDDS
                     ENIKSNFEEYLNGFSNNVKEIIGKFKFKDEINQLDKKDKLYAVLSKMYEVDLHINSVS
                     NNKMGYIYEEMLRRFTENSAAGEQYTPREVIRLCMEILFMGKENFLTEEGKVISIADF
                     CCGTGGMLSIAEDYVEKINPSAIVNVYGQELLDESFAICQADMLMKGQNPDNIRLGNT
                     LTQDRFNGEKIRFLISNPPFGVTWKDEEKKVKEEADLGFDGRFGAGTPRVSDGSLLFL
                     QNMISKMYDDEEGSRIAIIFNGSPLFTGDAGSGESNIRKWIIENDLLEGIIALPTDMF
                     YNTGIATYIWVLTNKKEAKRKGKIQLVNASEYYQLMRKSLGNKRKEISLEQIEQIKEI
                     YEKFEESENSKIFDNEDFGYRKVTIERPLKLSFKVNEEAIENVKNTTQFINLAVSKKK
                     DIEVKEKEEAEGKIKQDKLIKLLESFDNTLEYMDRDKFIKDLKAKSKEFDIQLSAGLI
                     KAIVNTIGVRNEDAEVCKDSKGNIESDSSLKDTESIGLKDDVYEYFEKEVKPHVNDAY
                     IDESSINNIGYEIPFTRHFYKYEELRSFAEIMKEVESLESEIALKIRKVLG"
     gene            9242..10633
                     /locus_tag="KR294_001189"
     CDS             9242..10633
                     /locus_tag="KR294_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010233411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HBH0239275.1"
                     /translation="MGYRYRSDDELKDSGVEWLGKIPKDWEVRQLKRVLSDRKENNEP
                     IKTSNILSLTIEKGVIPYSEKGTGGNKAKEDLTQYKLVYPNDIVLNSMNVIVGAVGLS
                     KYFGCASPAYYMLYKINANDDIRFYNYIFKSKLFQDSLKGLGNGIMMKQSETSGKLNT
                     IRMRIPMEKLSSVKIPIAFNLDQEKIANFLDEKTSQFDSIISKKEKLIERLEEAKKSL
                     ISEVVTGKVKVVKTDDGYELIKRSSEEMKDSGVEWLGEIPKEWDIKRLRFLGKLQNGI
                     SKSSDSFGYGYPFVSYSNVYRNIELPHIVEGLVNSTEEERKIYSVEEGDVFFTRTSET
                     VEEIGFASTCMKTIDNSTFAGFLIRFRPNDKRLYKGFSKYYFRCDLNRKYFVKEMNLV
                     TRASLSQNLLNNLSVVLPKYEEQVEIYNALELKVSYINLSINKLKYQIEKLKEAKQSL
                     ISEAVTGKIEILD"
     gene            10695..11966
                     /locus_tag="KR294_001190"
     CDS             10695..11966
                     /locus_tag="KR294_001190"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239276.1"
                     /translation="MDKNIFQININTDVLIRLRNQINEEYYISYRKEFYDKNNKKHRA
                     WDKICAIMDRLDDTVDYLNKLKLNTGKYRRSAFDFFEFMNQASVVMDCITHLAKIFEV
                     PYEEVETSTEIFNELGKEGKGTDKKYFEYLRSLCSVHPMETSRHKIYQENSFECSPYV
                     VWNDKSIWTNDASDLYAVVYTSKDNDSFKRIHIYMNQIFEYVKRRVNFIENIIEHIEK
                     YQQEIIEIFRNTPIKKEEDFESYIDYLRNLKKEIEIRYGNDSFHELNYLIELFDLPLS
                     NPDNEEKMNLYKNALKYAIKFEHNSIQNMTNEGYKNNGILYPQVNITTTLLEELISLN
                     SGSEERRKYRYAIEKTSYLSYDSCWSDREWAYDQIDDMMPFLERYVTFDKAQSDFEHY
                     VLVKLALYLECLENECLINKNVPNDKKFRIK"
     gene            12001..14982
                     /locus_tag="KR294_001191"
     CDS             12001..14982
                     /locus_tag="KR294_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HBH0239277.1"
                     /translation="MLPKEKHLEESIENHLVSIGYEQGHSQEFDLENCLFVDDLFRFL
                     ENTQKELLDEFKYNRGSNYKKAFIDLLNSNIKRRGLISVLRNGVEDIMMNGKFQLFYN
                     KPNLTTNKTAYENYKQNIFKITRQLKYSSKHNNTLDIVLSLNGFPVIVMELKNQFTNQ
                     NVYNAIKQFKKDRNPKETLFGFNQRVLVYFAVDTDEVYMTTELKGDKTFFLPFNKGNN
                     RGKGNPVVEGKEKTSYLWEEILTKDSLLDIIKRFYFIQEDDKGNQRAIFPRFHQLDAV
                     RKIVEDLKINKVGKNYLIQHSAGSGKTNTIAWTSHRLSSLHDEENNAIFDSIIVVTDR
                     KVLDKQLQNAIYQLEHKNGLVVKIDEDKNSSDLADAIVNRAKIIITTIQKFQYALPKI
                     EQLDKRRYAVIIDEAHSSTSGENMNALKETLAGKTLEEAKVIDAENEKNEKSSIDKMN
                     ELIEKRTNLGNISFFAFTATPKNKTMQVFGRIGEDGLPHEFHLYSMKQAIEEGFILDV
                     LKNFMPISVYYKVGKKIIDNPEFDKGEAKRAINKFVSLNEHNIRQKVETIVDDFVDNR
                     SMWLEGKAKGMIVTASRLHAVRYKLAIDQYIKEKGYDMKALVAFSGTVKDGDDEYTEV
                     GMNKEVAPDITDSNLPNIFDKNEFKLLIVAEKYQTGFDQPKLCAMYVDKKLDGVKTVQ
                     TLSRLNRTYPNKQTFILDFQNSVEDIQDAYKPYFEMTNIDKVTDPNVVNDLWYQLHEY
                     AVYTDEEVNDFTVLFYKEKRTSSQDAKMNNLIDKAVERYCYLEEDDEKKSDEFKKKCQ
                     KYITFYNFLIQIYPIKNLNLLRLQVYLVALLKKLPKKSKQRIDLDDMLSLDYYKLQKL
                     GLDDKKGTDISLYNGEGELVGISETATSRVSEADEEYLEDIIKKINDVFGVGLTEDDR
                     IMINTYEEMFKNDKDIMDIAKANSYEDLVSTFGKKYFKRGIVKTKNRNDRLVKEILTN
                     NNLQNYMIHYLAEKIYEEANR"
     gene            complement(15041..15211)
                     /locus_tag="KR294_001192"
     CDS             complement(15041..15211)
                     /locus_tag="KR294_001192"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239278.1"
                     /translation="MNNDKPFIEFEEEVDFILTECKKEGVSIDRDTIELILDLDLKFL
                     ELKGIATPLEDE"
     gene            15492..15827
                     /locus_tag="KR294_001193"
     CDS             15492..15827
                     /locus_tag="KR294_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239279.1"
                     /translation="MIKLWKKEDLNLLLEYPKEVVENVDNVINILDENYGCNRKLTDD
                     GGYVCIIEDIKEVENLKSNILKGLVEEFSDVIYEDEVNTYNSTLYLLSSDYSVTVISK
                     NEETEYLLK"
     gene            15891..16349
                     /locus_tag="KR294_001194"
                     /pseudo
     CDS             15891..16349
                     /locus_tag="KR294_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427593.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="JAB domain-containing protein"
     gene            16489..16782
                     /locus_tag="KR294_001195"
     CDS             16489..16782
                     /locus_tag="KR294_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239280.1"
                     /translation="MFKKENRYMTKEIAENLPIEIAILLWNLIDDLTTEKDYLQLFEI
                     NPIGLGVVEIVHKQEVPEYEARIYIQNDKIKDKLKIYVIDNVEYRTMMFSNEY"
     gene            16809..17405
                     /locus_tag="KR294_001196"
     CDS             16809..17405
                     /locus_tag="KR294_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239281.1"
                     /translation="MINNKSEIINKLFFNELKELIDKYNNIDDKTVDVIEKIFTCIED
                     EEIKNYLIRDNCKLQELVNTYNKLEDLNIDEAIFFAWYNLTINTISIDKASEYYDDLT
                     TSNYIEVENHIIYTNERDLRKYAEDELETMLSMEHHIDRLLHKDMLIDMWLNNTSKEE
                     VIEEILMSDDIEDILNLSPEYAFTLANGIEYRYSEKEE"
     gene            17558..17827
                     /locus_tag="KR294_001197"
     CDS             17558..17827
                     /locus_tag="KR294_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003487728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mor transcription activator family protein"
                     /protein_id="HBH0239282.1"
                     /translation="MTNNNNNCDYKGIYADMVEVLGEEIVIKLHKYYRGQQITFPMKL
                     YSIEYVERYIVKNYRTKTIKEMCRELGYTEGWIKQLINKNRLNSK"
     gene            17853..18095
                     /locus_tag="KR294_001198"
     CDS             17853..18095
                     /locus_tag="KR294_001198"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239283.1"
                     /translation="MILTVLAILMGTGIFFLINSMLDITYFGCGPIGFLWFGCFIVSY
                     AILTSLGGIVLGLLKWIVIGLIILFVIGLIANKIND"
     gene            18301..19434
                     /locus_tag="KR294_001199"
     CDS             18301..19434
                     /locus_tag="KR294_001199"
                     /inference="COORDINATES: protein
                     motif:HMM:NF012938.1,HMM:NF016983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosome-binding GTPase"
                     /protein_id="HBH0239284.1"
                     /translation="MQDFDFISETIKKFQSDLENMDKVNILVVGKTGVGKSTLINNIF
                     REELAETGIGRPVTQHLKKISKEGLPINLYDTKGLELEEDVQETIKKEILDEIENCNR
                     NSLERNDKSELMHVCWYCINTSVARCEETDIKWINELSEKIPVIVVLTQGFPRKKARE
                     LKSSIDDLNLNCKNVIPVLAEQLVEEEDEIVIKSYGLDKLVEVTYQVIPKEVKKAFVN
                     VQKVDIKKKVEESRKWVLGYVGGSGAIGFSPIPFSDAPLLATAQVAMISHITVIFGLQ
                     VDKALLTAIVSSIGGVTSATLLGKTLVSNILKFIPGAGTIAGGAISGSVAALTTTALG
                     MAYISVLEYILNENMKGNEVNNTEIAEKMKDAYKDQLGMLSKK"
     gene            20198..20443
                     /locus_tag="KR294_001200"
     CDS             20198..20443
                     /locus_tag="KR294_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239285.1"
                     /translation="MRSVTVEDGDERFAIEKIYIKSLQRYEVRICLYRDCRDRINKLI
                     PRPVDLTMDKFVALILVGLKAGVLDDDFKQELIKGLA"
     gene            20791..22152
                     /locus_tag="KR294_001201"
     CDS             20791..22152
                     /locus_tag="KR294_001201"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239286.1"
                     /translation="MKGNINKKDIDLSKITFDKFLEDEGLQNRERDYLYVDDYDNTLD
                     TQEFKLHIIEENTDNTYIDKDKYWYLDLDDSLFEYEEDEDTIAKTLYSLIDIRIKFLK
                     HVEYRKYINLGVIDEEYFDEIKSFLKFYIVAKTKKNELGNSNLKQMAIDIFDKERFED
                     DISDDDMENISEWIGEDQNFKMFYDKVCRDLSNSTQDKEILKLAGIRNNKVKHYKGRK
                     ISRKCKLELKSLTKMWEYETKLTHDANKAHKKIKSNMLEKMTDKNYKNIYEYLNNEII
                     NSNEEYKNIYFYSLELKLANELRKCTLKNLNKIKDIENQVKFISYTIAYIHIVPVLTI
                     REKLSDKLFNILSTNEGKDIEKFTKEVSLIMRIINIECLELLNIVSKNNYYKNFSEKE
                     LEEFKSIYNINNGRKSFENKYKIKVDYNIDDVRKYGEVIKAINIESKKKIVDRIKKKR
                     KSN"
     gene            22342..22659
                     /locus_tag="KR294_001202"
     CDS             22342..22659
                     /locus_tag="KR294_001202"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239287.1"
                     /translation="MTNFKSVKVELILLIECEEGNRNELEGMIDEGVLNEKEYSLTIL
                     GSTEYEDNARAIYILMNTGGSYEKNLQRLSRLHLKIENLLKDTNVKYRGISLVPNIVK
                     WDK"
     gene            22671..24434
                     /locus_tag="KR294_001203"
     CDS             22671..24434
                     /locus_tag="KR294_001203"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239288.1"
                     /translation="MSKAINREELIKLYEEIGLNVLDNNTVMNSSNKKICNFLVNIIE
                     QRVIDGKMYLCINAMGINGELLSEVILDSNTINRTTWVIENWGFKYSIDKKYINDFIE
                     LIQHLCMNIKTKYIYDHTGWIYQDNKWIYLHGGGVIGGSDVQVELDESIDNYILPDKI
                     SDINKACEMSLKLVDLIEDDKGIIFSSLVYLSPLIEIISRKIKPPENIVWTYGKTGSR
                     KTAVSKVVLSHFGDFNKKIPATFNDTITAIELKANKLKDSLYLCDDFAPKQDFRDKKI
                     QDSKAESIIRMYGDRVGKGRSSNKLDIKDAKRPRGMILITGEDVICGESSNARLLSIE
                     LNRSSVDLNILTELQNNSHLLGEAMRGYIEWLLSEMGNIDELSNILLYNFKSYRDEIR
                     EQYKDDIHGRTIESSAWILVGFSCMLNYIRDKGVIDKYEDDEYMDRAIKVVERLIEEQ
                     IKLISRNSPIDIFLNTLKESINSKSIRIATLNDQNQVIEDKLEYICGYKDKEYYYFYT
                     DKVYSFIEFENKKRGIHLGISQRQLVKQLRDSGIVKVDSNNDSPKKTIHTKDASDSTG
                     YTTIRPRMLQIERSIIENFQI"
     gene            24497..24652
                     /locus_tag="KR294_001204"
     CDS             24497..24652
                     /locus_tag="KR294_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239289.1"
                     /translation="MTETYKISIGRKDLYSKDYKVVERTDYEKRHTVNISRSLVDILS
                     ILVKEDR"
     gene            24739..26304
                     /locus_tag="KR294_001205"
     CDS             24739..26304
                     /locus_tag="KR294_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBH0239290.1"
                     /translation="MTGKKAVVYARFSSDNQRDESIDAQLRAINEYADKNNIKIVNQF
                     IDRAKSATSDKRPEFQNMIKFCEADTTGISMVIVHKLDRFSRDKYDSAMYKQKLKVKG
                     IRVVSVLENLDNSPESLILESVIEGMAQYYSANLAREVAKGQKENALKALHNGGDAPL
                     GYDVAHDKTYTVNEEEAQAVKIIFDRYIKGYSYSKIIDELNILGYKTKRGNKFGKNSL
                     HGILNNEKYTGVYVFNKTQRKGVDGKRNGHKQKSEEEIIKIEGGMPQIIDKGVFKQAQ
                     DMIQKRKKTPGAHKATTTYLLTGLIKCGECGHAFQGNKRKDSYGNEYVSYRCGCRKQK
                     RECNNREIKRDYLEEFILQELEKNILNDEAIPILSKALNEKLNDKNESNAELLKNLEQ
                     KLDKVNKEISNILNAIMNGIVNSMLKDKLDELEQVKFNLDLKMNELKIENKVVDGVGV
                     TEDQIRGMFSRFKEFVLERNIPECKKFIGDYIKEVIVYKDHIEVIFNVVFCFVDNDIT
                     HDLHIITERGKIT"
     gene            26450..27742
                     /locus_tag="KR294_001206"
     CDS             26450..27742
                     /locus_tag="KR294_001206"
                     /inference="COORDINATES: protein motif:HMM:NF014177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA adenine methylase"
                     /protein_id="HBH0239291.1"
                     /translation="MADIFTVLNYQGSKKRLLDFIYENTQEYIDSDKAFLDICSGTSA
                     VAYNMKRHFTVYTNDSENYAYQISNSIVKNNERYNFSQSDEMIIREKYNINLQRLNNI
                     FNDMVNQEDMLLEQEDADGLIELYSNCPCIWKNNVDIEIEGNTIQSIYDLRKCKRDIP
                     NVLFTLYYSSSYFGIKQSMEIDSIRYAIEFIESEITKSILFTSLFFAMKECVFAKDGH
                     MAQPLNMETGKKRMLRLKARSIYDIFIDKLKEFNTEEFVLSQKENKCFNKDFRTLLET
                     EESIKDEVGFIYIDPPYTDMQYSRYYHILNTVVLYDYPEISLSRGTISKGIYREGRYQ
                     SPLSQRKHALNEIDFLFSFCKENKINVALSYAYPIDTEKQATNRYTASIDDLINVAKK
                     HFGDNVKVVHEEYSHANNRNSDKKNVLEYLIMGIHNKE"
     gene            27745..29364
                     /locus_tag="KR294_001207"
     CDS             27745..29364
                     /locus_tag="KR294_001207"
                     /inference="COORDINATES: protein motif:HMM:NF013704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA adenine methylase"
                     /protein_id="HBH0239292.1"
                     /translation="MDKINKLKERIANIEATNKNDIYSSNLYWSQKPFNICDEIIEHL
                     SEDGDIIFDPFMGSGVTVIEALKKEYKRNAIGCDINDAPIFIVKTLLEKYNVPKIEKD
                     IKELNNKLSKLSTYYSTKCRECGEVVTISKTIFDKENRNAKCELKSIHYKCKECKNDF
                     KGEPNETEISKFFIDEELKNIDDFQFIANSRLAVGEGDTVRTIFSNRNLIVLDKILGH
                     IDEYKNSESYEPMKYILLSILHLSKITDTHSNSQWPLWIPKKDCVEKNVVELFIKNSK
                     KTIKALKLASKYLCENRENVELIKNLDRGKFKLIKDGVQNIEDDVIPNEFVDLIITDP
                     PYMGQVLYSEYMQLYKPFMDLEFELENEIVISSAPARDKGKVLYFDMMNSAFENISRV
                     LKVGKYMCMYFHDSNLDVWDNIIDIMTNNNLKYMGQIHVSKNKNTLKNILSPKKSLNG
                     DCIIFFKKDLNINYDINEVDNIEDKINNIAQAIIDIKGYASTPELYDNGALEYIISNG
                     KLKEISKKYKDLTSIFEQRFNWDKERGVWTV"
     gene            complement(29489..30640)
                     /locus_tag="KR294_001208"
     CDS             complement(29489..30640)
                     /locus_tag="KR294_001208"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239293.1"
                     /translation="MKKLTIRLKDDFHKDLLDLVAFKNDSINSYVINLIKNDLSKNTN
                     LLRSYDNMIRDNITNVLITQKINELKAIQDGIFKEYKVNDILSNSKIYEVMTANSLNH
                     ILIPGHSGSRDAKDEFGNEFEYKHFKKSSSNHSWTFNDFSDTSIAKLKKAKAVIFAHI
                     NDVDFPYPGKLDWYYSIPGDIMCEYLLKYTQSIQNSRKMINVSPNQLESRLNASKIIP
                     SAQNGVYDKYLSAIYKASSELEELTGVKNLLTSNKFWELIVALELNHQVNPEQGGREG
                     AHDAYDSEGNPYEYKVSKNHAWNFQDISDNVLNKYYNDKAIILAVVDKENIEVEHIYS
                     TEPADVVPLLRKKLQEKINRCLEKGSPIRRLQVSLSKSDLTRVNAKKLY"
     gene            31146..31361
                     /locus_tag="KR294_001209"
     CDS             31146..31361
                     /locus_tag="KR294_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3791 domain-containing protein"
                     /protein_id="HBH0239294.1"
                     /translation="MDERKLEFSIFCIEALAEKLNIDSEGVYKLLKHDTDILDNYIIP
                     CYEALHSQSKGYIVEDLMQVLKEKGVI"
     gene            31361..31840
                     /locus_tag="KR294_001210"
     CDS             31361..31840
                     /locus_tag="KR294_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3990 domain-containing protein"
                     /protein_id="HBH0239295.1"
                     /translation="MIVYHGSYCVVKTPSITFSRDSLDFGKGFYVTSIKTQAINWTER
                     FKKRGKKAYLNSYSLDIDKLKENCKVKIFDSYNLEWLDFIIECRNMSDIYMKYDIIIG
                     GIADDKIYNTIELYQDNLIEKDEALKRLKYYKPNEQICITNQNVIDKYLKFRYEEEV"
     gene            31846..32076
                     /locus_tag="KR294_001211"
     CDS             31846..32076
                     /locus_tag="KR294_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239296.1"
                     /translation="MEANKTLLQILYKKIILEFSKQTGKSLEESMDYLYTSETYKLIS
                     EGVSDMHCKGHIYLAQELMLENGLMYHKGYPR"
     gene            complement(32192..33358)
                     /locus_tag="KR294_001212"
     CDS             complement(32192..33358)
                     /locus_tag="KR294_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBH0239297.1"
                     /translation="MATKRANGEGSIGKYKDGWRSRIMIGYNEDGKPLRKEFYGKTQK
                     EVKDKLDAYKKQYYLSSDISDDKITLEHWFYNWLFEYRIKDLKPKSFERYESIYRNYI
                     KDTDLGNVKLKYLRVSHIQKYYNRLLDSNKSIPTIRQINTKLKTCLSEAEKQGLIQRN
                     YCTMVNIPVEKKENKLEILTLEQQKSFIKAIDGHKLEVLFLLALGTGLRLGELLGLKW
                     FDIDFKKSNLTVKRTLQRTYFIDKTGNRELKVLEQGPKTSNSYRTVPIPKDVLNKLKE
                     HKVNQNTDILKAGELYINNNYVFCNELGIPIDDKRPLRNLKSILNSLNIEPIKFHGLR
                     KTYATRLFENDVPPKTVQVLMGHYDISITLNIYTQVMEDKKVEAVEKLDKIFSL"
     gene            complement(33348..34100)
                     /locus_tag="KR294_001213"
     CDS             complement(33348..34100)
                     /locus_tag="KR294_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HBH0239298.1"
                     /translation="MNKSYIPKYTHKFPTNIPHGDKKYTLTYIRRMISEFVYDMGNLE
                     NNPFTFPEVQTLLDGITVGGHKLSDQNQILNIKSSWDYVIKLSNKENLSLNKDTICSI
                     HKIVAKDEALIVGDFRNGNIGIAGTTQYECIEATLLNDLFVNDINIINKITNPLEKAI
                     IINLWLSYCQFFYDGNKRTARLTSNLILINNDIGVLSIPAKHKQEYNTLMLNFYETLE
                     ADEVIKFLLEKCITFFDGYNYKSYKELFKNGN"
     gene            complement(34192..34683)
                     /locus_tag="KR294_001214"
     CDS             complement(34192..34683)
                     /locus_tag="KR294_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH0239299.1"
                     /translation="MMNNTIGEKIKQYRKSINMSRDELANKIGCSVHAIAKYEQNQRM
                     PSLDMIRKIATALSIAINKLIVEENDLDTLTNNNINLKVFDKELDLVIHILENYGYDI
                     KTDYKKKFEITDNADTIKPINLNFSDFKDFSKNLNWVINGLVENFIQENSNGLIEDED
                     EEY"
     gene            complement(34680..34878)
                     /locus_tag="KR294_001215"
                     /pseudo
     CDS             complement(34680..34878)
                     /locus_tag="KR294_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729178.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(34935..35696)
                     /locus_tag="KR294_001216"
     CDS             complement(34935..35696)
                     /locus_tag="KR294_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0239300.1"
                     /translation="MQIGKNLKKIRKQKELTQIQLAEISGISRNALINYENDKRIPSI
                     DTLSKLAKALKIEKTIFYFDIENEVMTNEDVLYLLQSLFPEEYYSFDEFLNAISNLME
                     DDIRITSSLLLGAWSDKDQYYKLGEKLELNENQVYNWILSDCISNTELDFSLHPDDIK
                     EIIKNDVLTKQSIDELLDIGLSEESIETIYDYFSDSTDNGSNIRLKKLISQKENITIK
                     NNDYFKLLQENNELKEKNEKLENTLKEIKKLLTKI"
     gene            35843..36043
                     /locus_tag="KR294_001217"
     CDS             35843..36043
                     /locus_tag="KR294_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0239301.1"
                     /translation="MGINLKIFRIKKGLKQQELADRVGISRYYLSNLETGKANNPSND
                     LMIKLSRALDTTVEELFFSKED"
     gene            36047..36361
                     /locus_tag="KR294_001218"
     CDS             36047..36361
                     /locus_tag="KR294_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239302.1"
                     /translation="MKENNNLEVLKTLQATLNIIVKNEEEAQEKKQGYKIIENAKRNK
                     AELITCKEASKLYPIGESKFRQLCHSKNKGFPCIWINNRVYIIKNKLDDWFIENANGI
                     KL"
     gene            36383..37126
                     /locus_tag="KR294_001219"
     CDS             36383..37126
                     /locus_tag="KR294_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239303.1"
                     /translation="MSNKGWIKLYRELLDKSIWKDIKPERKVILITLLLMASHKENHV
                     FIDNKKIKIKFGQFISSYSKIAERCGKGVSYQMVRSCLLVFKNAGFLTYETTNKYIVI
                     TIENWELYQENIENQQPNQQTINNQSTTIKNIKNENNIIYSEIISKFNSTCIELSKVK
                     KLTDTRKRRINSRIKEYDKETVLEVINIVSKTSFLNGNNNTGWKANFDWIMNSSNFTK
                     ILEGNYNSKEIVINKETGIYNPDDSQLKW"
     gene            complement(37832..39745)
                     /locus_tag="KR294_001220"
     CDS             complement(37832..39745)
                     /locus_tag="KR294_001220"
                     /inference="COORDINATES: protein motif:HMM:NF020926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1998 domain-containing protein"
                     /protein_id="HBH0239304.1"
                     /translation="MSIKLDDKTHNLRINQATSVFGPGAMLDFIDQTLMTAHPNYWTN
                     TIKIQDDRLQATLRVNELRTPPTIDDRSSVPFVRFPRWYFCPKCRKFMPIEDWEKLYK
                     NAHKDKPMKIPICLTCSTKKSTKQLVPTGIITICEHGHIDDFPWVKWVHFRNKSGRKE
                     ICENPQILMKTGKSNLGLEGIELECSCGAKANMKGAFMRLKSSKSNDYGVPSEYKEMF
                     KCSGNSPWYNKKVNKCTKYSFASQRGASNVYYPKIESSIIIPPYSDTLNSKVLSSKGY
                     DTFKKFLDRAIKKNKLERFMDEDFEDFASDIAKETGFDTDKVSIVLKDLLPFEDSSPS
                     TTTRNQYREEEYEALIGNIDAKSKKTNDFTIEEQNLSDYDIPNFSKIVLVKRLREVRA
                     LTGFSRVNPPDNNIFGEEDIDDSCNDTKVISLRSRDCKKSFYPASEVRGEGIFIEINN
                     DMVKSWISSNPKIQDNASILNSRYNKDINVNDKAYRKITPKFLLLHTLAHLIIRELSF
                     VCGYATSSLRERIYCNNSENEKVMSGILVYTASGDSEGTLGGLVRQGMHDSLPSILNS
                     ALNRALWCSNDPICIDSTGQGRNSLNLGACHSCTLLPETSCEEYNLLLDRSMLIGDMD
                     NRDIGFFKNLILI"
     gene            complement(39747..43274)
                     /locus_tag="KR294_001221"
     CDS             complement(39747..43274)
                     /locus_tag="KR294_001221"
                     /inference="COORDINATES: protein motif:HMM:NF012493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HBH0239305.1"
                     /translation="MNCSELRDKTLDLVRKELLGPGSEDLCENIKYEIITDSPIERYS
                     TGILYPLNNNIDVSNTSEYDGEDNVFTSDDTQNELDRAISMSNETLPSSMGMTFFLKK
                     DAEVINFRVNYATYRNALYTDCHVKYTGDDFYSSNTINEYVELRGSFLYLKQKLTSEK
                     VYNLLKKHDLLDNAEAKFVLYKLANQCPDDENKTGGYVRVPHENLIVSIDMDKNYIKK
                     PISKDLDIVLSKRIYSNDFVSITCMLVNSQSGPKKYNNTIFQPELMVLAEDNNDLEFI
                     DIFTAGSVNTFKKLDSEEISLDLLYRNKKTFATGHGVAIDQDIQNDALIKLCTEFIPH
                     FEVPKLDFNVDELSDVSRELLSMKNLSDISDLSKDKKIYFLYKFVDAYDIWIDDLEED
                     SKDLSDVFKDVAYEHIKNCRDTKSRMLEGINLIKSNDEVYRAFSLMNRAILMQRCHSI
                     HITDRLPGSNNLDYIDYSNDNSAWRPFQLAYILTCLSSIENPDSKHRDLVDLLWIPTG
                     GGKTEAYLGLSAFTIFLRRIRNKENGNGTAIIMRYTLRLLAAQQFIRASILICACEII
                     RKENKSELGKKEISIGLWIGSDQTPNFNDEAEEMLNNLTGNNIKFRSSINSEYELDNL
                     KSKYNKFQLLKCPWCGTKLVKEWDKTSKKAVGDWGYRIKSRPKKFYLCCPEEDCSFED
                     MLPIQVVDEEIYNNPPTLLFGTVDKFAMITWTTEVASLFALDDDNSNLSPELIIQDEL
                     HLISGPLGTMVGLYETALDAMCSYKGIKPKIIASTATIRKAQNQVKNLYNRNVAQFPP
                     PGLTSSNSFFVKEMPLSKKRGRLYVGVIPSGKTQVTVEVRLMSALLQRLKMMENVELN
                     LLDKYWTLVSYFNSIRELGKCSTLLNDDIKDNMERLCKRVSAHPYQSLRNLNEQRELT
                     SRLTSTKINTTLDELSNTLTSNNLTVDTLLASNMISVGVDVDRLNLMVVVGQPKLTSE
                     YIQASSRVGRSNEGLIFTLYNPTKTRDRSHYEQFFSYHQSFYKFVEPTSITPFSEPAR
                     ERGMHAVLISMIRHILGLQANDLASRFSKNMDGVEDLKNFIIDRSIDIFRENNQNADD
                     NIVNEFKSEISSELDIIMDLWHDKAQISDKDNLLHYYKRPSKFDNKIYNNLLIPYDKD
                     VITNEKQTLNSMRNVDKQCTVEIIELEEN"
     gene            complement(43292..>44580)
                     /locus_tag="KR294_001222"
     CDS             complement(43292..>44580)
                     /locus_tag="KR294_001222"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239306.1"
                     /translation="NELSDNNTKFNTLNKLVSSYKYKTFTPNTPVILLQKQYEAIILK
                     NLLKSRNINLQVISAEKFKDSKTIKNLIMFGFYDLKYLDILNSDLIINITLYLYNSEL
                     SKYNYYMNQINSARNKIEKNNKIYNLLDIKPFKPTYETNKLEAYSTDSPISDDDSMDE
                     YISNYKFDINLNEIILSLSINQGIYNSKKEHVTSFMISDNNEYIFCTKKAIAYSIDWD
                     KKSVRKKKLSEAKVNDWFLFVDDYLNEEGELVINVIQKLLELNLLPSHYLDDYKLTNS
                     WKSELKNYISYSKYNYNDVSNSLAVLGEKINPITIKNWVTNKRLIGPIYLKTFEKIFK
                     VIDSKLDHTEVYDATKSIRSLHTKIKKSIDTFVSDNFFSSKSDIIKDEVSAVVLSMLG
                     NTNDYVTPVQIREIHSCDKYLSPHLVNKVLDLYSVY"
BASE COUNT        17667 a         4993 c         6935 g        14985 t
ORIGIN      
        1 ataacttcat aaacttaaaa aatttcagaa acaaagatac tttaatttaa ttaaaaacag
       61 aaaaattaaa atctttagaa aaaatttaga aatttataaa taatatctta agttttagaa
      121 tttattatga aaatacagta aaaatttata aaaataaaat tctataaaat tgtttctggg
      181 ggtgtattta tatatggaaa tgaaaatagc agtatccaat cttagtaaaa gatttgggaa
      241 aaaacaagct cttgataata taaatcttga aatcgacagt ggtatgtttg gtcttttagg
      301 aagaaatgga gcaggaaaaa ccacatttat gagaatttta gccactttat tatcaaaaac
      361 agaaggttca atacatatgt gtggagttcc tattgagaat actaaggaaa ttagaaatat
      421 ggttggttat ttgccacaag acttttcaat gtatcctaac atgacagtat ataaagcaat
      481 ggattattta gcagttttat cggatatacc actaagaaaa agaagaaaaa ttatagcaaa
      541 gttattaagc aaagtaaacc ttactaatta tcaaaatgtg aaagtaaaat ctttatctgg
      601 aggtatgaat agaaggcttg ggatagcaca agcattaatt cataatccca gagttttaat
      661 agtagatgag ccgacagcag gtcttgaccc agaagaacgt ataagattta gaaatttact
      721 atgcgaaatt gcaaatgata gaatcgttat tttatctaca catattgttg gagatataga
      781 agctacatgt gaaaacgtag ctatattgaa tagtggaaaa gtcatataca atggctcaac
      841 agaagcatta gcaaaactag ctgaagggaa agtatatagt attgaagtag ataaaaaaga
      901 tattgaaaat ataaaaagta gatttatagt tataggaatg ttgactcatg gtggaaaggc
      961 tatacttagg attatatcag atgataaacc ttttgagaca gcagtaaatt gtaatccaac
     1021 tattgaagat ggctatatgc ttataatggg aggagataat atatgaatct atttataaaa
     1081 gaatgtaaaa atatattaaa gagtatgata tattatattt ttattgtagt tttagttttt
     1141 ttctatattt ctcaacttgg aagttcagtt tcaaatgatg taagtaaaaa tattcctaat
     1201 gatggaaatc cattagttgc tccacaaaaa gtagagaata ttgaggaata ttactctgta
     1261 cacaatcaat atccatatgg tcaaaaagaa tctatgaaaa cagaaaaagt cattccaaat
     1321 gcaactataa acctaattag agaatatcaa aaaaacacat atacaacgta tccaacaggg
     1381 gtagttaagt atataaaatt agaccaaaat aaaacgaaga ccatagaaaa atatatagaa
     1441 gaaataactg gtaaaagtat tagcgaaata aattcacttt ggaaaactga tgaaagtata
     1501 aaaatagatt attctaaagt atctcttgaa agatttgaag aaataatgca aagagtagac
     1561 gacattttag gaggagggtc tgcatatgct tttgacaagt tacaaagatt tggagtagtt
     1621 ccagttacct atgatgaagc tatgaagaat tacaactata caatacaaaa agataaagtt
     1681 agtaatgggt atgcaagaat tttttgcgat tatataggta tagttttaag tatatttcca
     1741 gtatttgtgg cagtttttat gtcacttaaa gataagcgtt caagaatgag agagattatt
     1801 tattcaaaac aagtatcttc atgcaaaata gttttatcaa gatattttgc acttgtcttt
     1861 atgatgatat tgcctgtatt aattttaggt atgaaagatt tacttccttt gattttcttt
     1921 gctaaagata aaggtatatc tattgataac ttagcattta taaaatatac attatggtgg
     1981 atactaccaa ctcttatgat agttacagct gtaggaatga gtattactat attaacagat
     2041 acaccagtag caattattgt gcaattaatt tggtggcttt acagtataaa ttctacagga
     2101 ctcaaaggtg attattcaac aatggggcta atgataagac ataatagtgt attaaatggg
     2161 gatattatta tacaaaactt caatcaaatt atgattaata gaattgtgat aagtttggga
     2221 gcattggtgc ttgttttgtt agctatattc ttatatgagc aaaaaagaag ggggaatctt
     2281 gatgtttggg caaagttttc aaaactgttt agttctaata aaagaaaact tcaaattaag
     2341 cactttaact aatttaatat gttcaattat attgctatgt atgattcctc taatacaagg
     2401 agtagctaat ttagacagaa tttcaacagc tatatgttta gaaaattatg ttgcaataat
     2461 agggatagta atgttggtac ctgtattttc gctagagcaa tcaaaagaaa ttgatgagat
     2521 agtatcttca aaagcattat ctcaagttat tgtacaatta attaggatac tgatgtcaat
     2581 tataggtata gtggtattaa tcataggttt tgtaaatgtt ttaatatatc ttggatgtaa
     2641 ttttccagta gttgagtata ttattggaag tttcgcatca gctatgttta taggaagttt
     2701 aggaatgttt ttctcaaatt tatttaataa tacaatcata ggttatatga tatctatagg
     2761 atatttaatt ttaaatatga tgactaaagg caagtatgtt ggaaaatttt ttataatgtc
     2821 tatgagtcaa ggtagttttg atgagaaata ttggctgata cttggaagtg ttgtgttgat
     2881 aattgcatct ctcttaataa aaccagtaaa aaggaagatt agataataaa atgagagctt
     2941 agataaaata aaggtaatgc aaataaaaag tacatttatg aaatataaat ctatttttat
     3001 atacacaaac ctacttacaa tctctttatg tatgtagata gatttatata tccgtagtat
     3061 aaaatatata tgtataccga attttatcaa aagctctcaa atttatattt caaagacact
     3121 tattgctatg acctacacat atgtattttt tcattttaat tgttgtatta acaataggac
     3181 tattgttata aactattgat acctcataac aaaaaattct ccatctccta aatgcgtttt
     3241 ttgtacctta gtctcaacta ttttaaatcc ttgagactca taacatttta cagctctcat
     3301 gttccaggtt cttacattta atacaattgg tttagtacta tatttatttc tacattcttg
     3361 taatcctagg ctaattattt ctttaccaat tcccattcca caataattcg gtttcaacca
     3421 ataccaaaga atacagagct tccttcatct aataagttta taaaacctat caattcttta
     3481 ttgtcattta taaaacttat aaaatttttt cttttatctt cttttgctag tgaaaaattc
     3541 ttctttttaa tttcctccca tggaggtaga ttgtatattg aatatttacc ttcatatttc
     3601 caattagtaa cttcaatagc atgttcttca gtaaatttaa ctttatttaa attcatatgt
     3661 cctcctatta aaatatttaa ggtaattaat ggtattttaa agttttagaa aataagtaaa
     3721 actatttata tttatccata aaatctttaa aaattttact aacaattctt gtaccctgta
     3781 ctttttattg gattcacaga agactataaa ctaattttga atcaccttct aattcaaaaa
     3841 catcacgata tatataattt cttagcttga ttaaattctg ttaaatccgt ttcttatagt
     3901 tgtataatca acatcaatat ctttatgtgt attagttaat ttattggttt taggaactta
     3961 ttattaatat attgtatttg ctccaataat ccaagtagta ggtaaattat aggcaaatta
     4021 tcaaatgtat atctatccat gcttaaactt tagagataca ataactacta aattagtgtt
     4081 ctagtagtta caaaaaagaa tctttaaaaa tattaattta acttatattt tttaataaat
     4141 tttctaaaat ttaataagtt aatttaatta tagctctaaa tgatattttc tacagatata
     4201 attttaaaaa ggtgtgtata agaacaaatt cacttaaatt tttaaaatca aataaagttg
     4261 aatctcttga ctaccttgat tgttttatga aattaatata gatgtaaact ttactattaa
     4321 aaaaatacaa gattttagat aagttaatgc taattataaa taataagata agaaatataa
     4381 tatgacataa gggctaggaa taagataaat ataatcaaag aataagatat gagaataact
     4441 accaagagaa atcattacct taatatgttt ataaatgtta gactatgttc ctaaattgaa
     4501 ttttatatat caagtataat aactttacag aatgtggaaa tttttattta aagaatacac
     4561 ataaatattt ccacactctg attttataat aatctaataa aatttatagt gactttataa
     4621 aatcaataat gatttaataa atatttataa aacaactatt tttgcttaga aactttatta
     4681 ttcatattat cattagtagg cattgctcca aaacttagtt tttcatacat tacttgagtt
     4741 ggagctagcc aaactgtacc actaccagta aatgtattta agaaaccttc accatttaaa
     4801 gcagaaccaa ttaaagattt atctgatttt gtaacagaaa aattaacacc agatgttctt
     4861 gctattgcaa agttaccatc tacctttaat tcttcaccat ttttcaattc atactctaca
     4921 atttcacttt gaggtacaac acattccaga acgattacac cagtaccact taattctatt
     4981 tggaagaagc cttcaccacc aagtaaagca gatgagaagt tcttttgtgt aaatgctttt
     5041 acttctattg tatcagagca acaatagaat aatcctttat caacaattat agaatcatta
     5101 tcaagactca taaataaata atgtctaaaa gaaggttcca aataaacttc tccagtacct
     5161 ttgtatacag gtttcatcat tgattcatta gtaagtgctc ctgatattcc ttttttaaaa
     5221 agacctccaa caccaccaat cttagtttca gaagatatat ttcctttata atagtataat
     5281 gcaccagctt ctgtttttat tgatgaatta tttaatttta tcttaatttg tctagctttc
     5341 aaaccagctt ctctagcaaa atataatccc attgccatta atgggctaga agctccctca
     5401 agtttttcaa attctaatat ctcaaattcg cttttgccat ctgatgcatt ttctaaaatt
     5461 tttacttttt tgcttaaatc catacaaatt tctccccact atgataaaat ttatctctaa
     5521 aatattataa gatataactc tatattacat tttttttgaa aaaatcgcta ctttatcatc
     5581 aaatttttac atatttttaa gaagtttttg aaatgtttag atttaagtta agttatttaa
     5641 ggatgtatag ttatttcaat agacattttg agtattattt atcatttgtg ggtattatat
     5701 tttatgggca tgttaaaatt atttagaaga tagaagatag aagatagaag atagaagata
     5761 gaagatagaa gatagaagat agaagataga agatagaaga tagaagatag aagatagaag
     5821 atagaagata gaagatagaa gatagaagat agaagattta taatatgtaa tatttttgtt
     5881 ttgaaattta taaattagta ttactggtta gagttagttt agtattaagt atattcgaag
     5941 tagtttttta gctattttca tacatttata ttacttaatt atatatagcc taactaactt
     6001 aatatatcag tgaaatattg actaaaatgc ctaaatatgt tatcatacaa gttagtcaaa
     6061 taatttggca acattaaata tttagtaaat ttctaacatt tatggaacaa atttctagca
     6121 aagaaggtga gatttatatg gctggtaaaa aaatattagc aacaaacaaa agagcaagac
     6181 atgaatattt tatagaagaa acttatgaat gtggaattga attaaaagga acagaagtaa
     6241 aatcaataag acaaggcaaa gttaacctaa gtgatggatt tgcatctgta gataatagcg
     6301 aagtattttt aaaacaagtt catataagtc catatgagca aggaaatata ttcaatgttg
     6361 attctttaag agttagaaaa ctattacttc ataagcatga aataagaaag cttattggag
     6421 caactactat aaaggggtat tcacttatac cacttagttt gtatctaaaa aacggtaaag
     6481 ttaaagtaga gattgcctta gcaaaaggta aaaaactata tgataaacgt caagatatgg
     6541 ctaagaaaga tgcacaaaga cgtatagaaa gagaaatgac aggtaagtat taaactagat
     6601 aaaactgtat tttttagaat aaaattcttt attatctaga acataacatt gatttttatt
     6661 cttaaaagta ttatattata tatacattaa aaatttaata aaaatggtga taaagtttga
     6721 gaaaagtcta ctggactata aactactcaa gggggcgtaa aggtttcgac gtgggtttgg
     6781 aacttgaggc tgcatgtcgt gttactctgg gtcacgtaaa aactggggaa ctttaaaata
     6841 aacgcagacg ataatttcgc gatagcagcc tagttgctgc tcgtccctct tagtcctcct
     6901 gccgactaag actggacgtc attatgcagg gaactacttt aggggtgtct cgacttgaag
     6961 tagattaatt gggactggct aagcatagag cctgccactt ggcgctatgt gaggtgagat
     7021 attagtgaag ttggctaagc atgtagatgc agcaaggaaa agatttgcgg acaggggttc
     7081 gactcccctc gtctccacca ttgaaatcca cgaaaacata ttgatagttt agtcaatatg
     7141 ttttttttgt gccttgaaat gatataatta taatataaac taatgtaaaa tttaactaaa
     7201 aggagatagt ataagtgagt atagataata attttaacca tgttgcattt ctgtggaata
     7261 tagcagaaag tttaagaggt acatataaag aagaagacta tagaaaagta atgttaccac
     7321 taatagtaat aagaagattt gattgtctat tagatgatta tgatagagaa ataataaaat
     7381 cagtatacga agaatacgac ttcttaccag aagaagaaag agatgagcta gtaatagtag
     7441 acttaaaaga aaatcacgac ataaacttac aattttacaa tgtaagtgat tttacatgga
     7501 aaaaactatt agatgatagt gaaaatataa aatcaaactt tgaagaatat ctaaacggat
     7561 tctcaaacaa tgtaaaagaa ataataggta aatttaaatt taaagatgaa ataaatcaat
     7621 tagataaaaa agacaagcta tatgcagttc ttagcaaaat gtatgaagta gatctacata
     7681 taaactcagt atctaacaat aaaatgggat acatatacga agaaatgtta agaagattta
     7741 cagaaaactc agcagcagga gagcaataca caccaagaga agttataaga ctttgtatgg
     7801 aaatactatt tatgggtaaa gaaaacttcc ttacagaaga aggaaaagta atatctatag
     7861 cagacttttg ttgtggtact ggaggaatgc tttcaatagc tgaagactat gtagaaaaaa
     7921 taaatccaag tgcaatagta aatgtatatg gacaagaact acttgatgaa tcattcgcaa
     7981 tatgtcaggc agatatgcta atgaaagggc aaaatccaga taacataaga cttggaaata
     8041 ctttaacaca agatagattt aacggagaaa aaataagatt tttaatatca aatccgcctt
     8101 ttggtgtaac ttggaaagac gaagaaaaga aagtaaaaga agaagcagac ttaggttttg
     8161 atggaagatt tggagcaggt actccaagag taagtgatgg ttcattactt ttcctacaaa
     8221 atatgataag taaaatgtat gatgatgaag aaggaagtag aatagctata atatttaacg
     8281 gaagtccatt atttacagga gatgcaggaa gtggagaatc aaacattaga aaatggataa
     8341 tagaaaatga tttactagaa ggtataatag cactacctac tgatatgttc tacaatacag
     8401 gaatagctac atatatttgg gtacttacta acaaaaaaga agctaaaaga aaaggtaaga
     8461 tacaacttgt aaatgctagt gaatattatc aattaatgag aaaaagctta ggaaacaaaa
     8521 gaaaagaaat aagtcttgaa caaatagaac aaataaaaga aatatatgaa aaatttgaag
     8581 aaagtgaaaa tagtaaaata tttgataacg aagattttgg atatagaaaa gtaacaatag
     8641 aaagaccttt aaaactaagc tttaaagtaa acgaagaagc tatagaaaat gtaaaaaata
     8701 ctactcaatt tataaatctt gcagtttcta agaaaaaaga tatagaagtt aaagaaaaag
     8761 aagaagctga aggaaaaata aaacaagata agttaataaa acttttagaa agctttgaca
     8821 atactttaga gtatatggac agggataaat ttataaaaga tttaaaagct aaatcaaaag
     8881 agtttgatat acaactttca gcaggactta taaaggctat agttaatact attggtgtaa
     8941 gaaatgaaga tgcagaagtt tgtaaagata gcaaaggtaa tatagaaagt gatagttcat
     9001 taaaagatac tgaaagtata ggtcttaaag atgatgtata tgagtatttt gaaaaggaag
     9061 taaagcctca tgttaatgat gcttatatag atgaaagtag tataaataat ataggatatg
     9121 agataccatt tactagacat ttttataagt atgaagagtt aagaagtttt gctgagatta
     9181 tgaaggaagt agaaagttta gaaagtgaga tagcactaaa gataaggaag gtgctagggt
     9241 aatgggatac agatatagaa gtgatgatga gttaaaggat agtggagttg agtggttagg
     9301 gaagattcct aaggattggg aagtcagaca attaaaaagg gtactatcag atagaaaaga
     9361 aaataatgaa cctataaaaa caagtaatat actgtcattg acaatagaaa agggagttat
     9421 tccatattct gaaaaaggta ctggtggtaa taaagctaaa gaagatttaa cacaatacaa
     9481 attagtatat ccaaatgata ttgtattaaa tagtatgaat gtaattgttg gtgcagtagg
     9541 actatcaaaa tattttgggt gtgcgagtcc tgcatattat atgttatata aaataaatgc
     9601 taacgatgat ataagatttt ataattatat ttttaaatct aaattattcc aggatagttt
     9661 aaaaggatta ggtaatggaa taatgatgaa acaatcagaa acttcaggta agttaaatac
     9721 gatcagaatg agaattccaa tggaaaaact aagttcagta aagataccaa ttgcttttaa
     9781 cttagatcaa gaaaaaatag caaactttct tgatgaaaag acttcacagt ttgattcaat
     9841 tatatctaag aaagaaaagt taatagaaag attagaagaa gcaaagaaaa gccttataag
     9901 tgaggttgtt actggtaagg ttaaggttgt taagactgat gatgggtatg agcttataaa
     9961 gagaagtagt gaagagatga aggatagtgg agttgagtgg ttaggtgaga tacctaagga
    10021 atgggatata aaaagactta gatttttagg aaaactacaa aacggtataa gtaaaagtag
    10081 tgattcattc ggttatggtt atccatttgt tagttatagt aatgtatata gaaatataga
    10141 attaccacat atagtagaag gtctagtaaa ttcaactgaa gaagaacgta aaatttattc
    10201 agtagaagaa ggagatgtat tctttacaag aacttcagaa acagtagaag aaattggttt
    10261 tgcttctacg tgtatgaaaa ctattgataa ttctactttt gcaggatttt taataaggtt
    10321 tagaccgaat gataaaagac tatacaaagg attttctaaa tattacttta gatgtgattt
    10381 aaatagaaaa tattttgtaa aagagatgaa tttagtaact agagcatctt tatctcaaaa
    10441 tcttttaaat aatctttctg ttgtattgcc taagtatgaa gaacaagttg agatatataa
    10501 tgcacttgaa ttaaaagtta gctacattaa tttatcgatt aataagttaa agtaccaaat
    10561 agaaaaacta aaagaagcta aacaaagttt aataagtgaa gcagtaacag gaaaaataga
    10621 gatactagat taacttctag tatcttaata tagatataga ttatacatac aaagttaaat
    10681 aaaagggaga attaatggat aaaaatatat ttcaaattaa tataaataca gatgtactga
    10741 taagattaag gaatcaaata aatgaagaat attatatatc ttatagaaaa gaattttatg
    10801 ataaaaataa taaaaaacat cgcgcttggg ataaaatatg tgcaataatg gataggcttg
    10861 acgatactgt agattattta aataaactca aattaaatac aggtaaatat agacgaagtg
    10921 catttgactt ctttgaattt atgaatcagg cttccgtagt aatggattgt ataacacatc
    10981 ttgcaaaaat atttgaagta ccatatgaag aagttgaaac ttcaactgaa atttttaatg
    11041 agcttggaaa agagggtaaa ggtacagata aaaaatactt tgaatatcta cgttcattgt
    11101 gttcagtcca tccaatggaa actagtagac acaaaatata ccaagaaaat agttttgaat
    11161 gtagtcctta tgtagtttgg aatgataaaa gtatatggac taatgatgct agcgatttat
    11221 atgcagtggt atacacaagt aaagataatg atagtttcaa aagaattcat atatatatga
    11281 atcaaatatt tgagtatgta aaaagaagag taaattttat tgaaaatata atagaacata
    11341 tagaaaagta tcaacaagaa ataattgaaa tttttaggaa tactccaata aagaaagaag
    11401 aagattttga aagttatata gattatttaa gaaatctaaa aaaagagata gaaataagat
    11461 atggtaatga ttcttttcat gaattaaact accttataga attatttgat ttgccattat
    11521 caaatcctga taatgaagag aagatgaact tatataaaaa tgctttaaaa tatgctatca
    11581 aatttgagca taatagtatt caaaatatga caaatgaagg ttataagaat aatggaatat
    11641 tatatccaca agtgaatata acaactacat tactagaaga gctaatttca ttaaatagtg
    11701 gtagtgagga gagacgtaag tacagatatg caatagaaaa aacatcatat ctaagctatg
    11761 atagttgttg gagtgataga gaatgggcat atgatcaaat agatgatatg atgccttttt
    11821 tagaaagata cgtaacattt gataaagctc aaagtgattt tgagcattat gtattggtaa
    11881 aactagcact ttatttagag tgcttagaaa atgaatgttt aataaataag aacgttccta
    11941 atgataaaaa gtttcgtatt aaataattat agctaataaa atagggagag ggaggatatt
    12001 atgttaccaa aagaaaaaca cctagaagaa tctattgaaa atcatttagt ttcaattgga
    12061 tatgaacaag gtcattcaca agaatttgac cttgaaaatt gcttatttgt agatgattta
    12121 tttagattct tagaaaatac tcaaaaagaa ttactagatg agtttaaata caacagggga
    12181 agtaattaca aaaaagcttt tatagattta ttaaattcaa acatcaaaag aagaggtctt
    12241 ataagtgtac ttagaaatgg tgtagaagat ataatgatga acggaaaatt tcaattattc
    12301 tacaacaaac caaatctaac tactaataaa acagcgtatg aaaattataa acaaaatata
    12361 ttcaaaataa caagacaatt aaaatatagc tcaaagcaca acaatacttt agatatagta
    12421 ttatctttaa atggatttcc cgttatagta atggaactta aaaatcagtt tactaatcaa
    12481 aatgtgtata atgctataaa gcaattcaaa aaagatagaa acccaaaaga aactttattt
    12541 ggatttaatc aaagagtgtt agtatatttt gcagtagata ctgatgaagt ttatatgaca
    12601 acagagctaa aaggagataa aacattcttc ttaccgttta ataaaggtaa caatagaggt
    12661 aagggaaatc ctgtagtaga aggaaaagaa aaaacttctt atctttggga agaaatactt
    12721 actaaagata gtttacttga tattataaaa agattttact ttattcaaga agatgataaa
    12781 ggtaatcaaa gagcaatatt tccaagattt catcaattag atgcagtaag gaagatagta
    12841 gaagatttaa agataaataa agtaggtaaa aattatctta tccaacatag tgctggtagt
    12901 ggtaagacta acactatagc atggacttca cataggttat caagtcttca tgatgaagaa
    12961 aataatgcta tatttgactc tataattgta gttacagaca gaaaggtact tgataaacaa
    13021 ttacaaaatg ctatatatca attagagcac aaaaacggac ttgttgttaa gatagatgaa
    13081 gataaaaatt catcagactt agcagatgct attgtaaata gagcaaagat tattataact
    13141 actattcaaa aattccagta tgcactacct aagatagaac aacttgataa aaggcgttat
    13201 gcagtaatta tagatgaagc acattcttca acatctggtg aaaatatgaa tgcattaaaa
    13261 gaaactttag caggaaagac tttagaagaa gctaaggtaa ttgatgcgga aaatgaaaag
    13321 aatgaaaagt ctagtataga taagatgaat gagcttatag agaaaagaac aaatttagga
    13381 aatataagtt tctttgcttt tacagctact cctaagaata agactatgca agtatttggg
    13441 aggataggtg aagatggact acctcatgaa tttcatttat attctatgaa acaagcgata
    13501 gaggaaggat ttatattaga tgtactaaaa aactttatgc ctataagtgt ttattacaaa
    13561 gtaggaaaga aaattattga taaccctgag tttgataagg gagaggctaa gagggctata
    13621 aataagtttg ttagtttaaa tgagcacaat ataaggcaaa aggttgaaac tatagtagat
    13681 gattttgtag ataataggtc tatgtggtta gaaggtaaag ctaaaggtat gatagttact
    13741 gcaagtagat tacatgctgt tagatataaa ctagctatag accaatatat aaaagaaaaa
    13801 ggatatgata tgaaagcact tgttgctttt tctggtactg taaaagatgg tgatgatgag
    13861 tatacagagg taggtatgaa taaggaagta gcaccagata ttactgattc aaatttacct
    13921 aatatatttg ataaaaatga atttaagcta ttaatagttg cagaaaagta tcaaactgga
    13981 tttgaccaac caaaactttg tgctatgtat gtggataaaa aactagatgg tgttaaaact
    14041 gttcagactt tatcaaggct taatagaact tatcctaata aacaaacatt tatattagat
    14101 ttccaaaata gtgtggaaga catacaagat gcatataagc catattttga aatgactaat
    14161 attgataagg taacagatcc aaatgtagta aatgaccttt ggtatcagtt acatgaatat
    14221 gcagtatata ctgatgagga agtaaatgat tttacagtat tattctataa agagaaaaga
    14281 acttcttctc aagatgctaa gatgaataat ttaattgata aggcagttga aaggtattgt
    14341 tatttagaag aagatgatga aaaaaaatct gatgagttta agaaaaaatg tcaaaagtat
    14401 attacttttt ataatttttt aattcagatt tatcctataa agaacttaaa tcttttaaga
    14461 ttgcaagttt atttagtagc acttttaaag aagttaccta aaaagagtaa acaaagaata
    14521 gaccttgatg atatgttaag ccttgattat tataaattgc aaaagcttgg attagatgat
    14581 aaaaaaggaa cggatatatc cttatataat ggagaaggtg agttagttgg tatatctgaa
    14641 actgcgactt ctcgtgtaag tgaagctgat gaagagtatt tagaggatat aattaaaaaa
    14701 ataaatgatg tttttggtgt aggacttacg gaagatgata gaattatgat aaatacttat
    14761 gaagagatgt ttaagaatga caaggatatc atggatatag ctaaagctaa tagttatgaa
    14821 gatttagtta gcacttttgg taagaagtat tttaagagag gtatagttaa aaccaaaaat
    14881 agaaatgata gattagttaa ggagatatta actaataata atttacaaaa ttatatgatt
    14941 cattatttag ctgaaaagat atatgaagag gcaaatagat aagataccta tagagagcta
    15001 attaactctc cataggtact ttattatgag ctattgtata ttattcatct tctaaaggtg
    15061 tagcaattcc ttttaattct aaaaacttta agtctaaatc aagaataagc tctatagtat
    15121 ctctatctat agaaacacct tcttttttac actcagtaag tataaaatca acttcttctt
    15181 caaactctat aaatggttta tcgttattca tatttttgct cctttgatta aatataatgt
    15241 atttacttta aattatatca aagaagagaa aaaaataaca ttatttgtaa aaaactatat
    15301 atatataata tatagtttta ccatatatag ataaactgtt tttaattaaa ttataaatat
    15361 atattatatt aatgaatcta tattaaatag atagttgagt aagtagtaat accaaaaata
    15421 ttaaaaagag atgttggtag aaatacgaac atctcttttt tagtgcaaaa aattaaaagg
    15481 aggaagttaa tatgattaaa ttatggaaga aagaagattt aaatttatta ttagaatatc
    15541 caaaggaagt agttgaaaat gttgataacg tcattaatat tcttgatgaa aactatggat
    15601 gtaacagaaa attaacagat gatggtggat atgtgtgtat aattgaggat attaaagaag
    15661 tagaaaactt aaaatcaaat atattaaagg ggttagtaga agagtttagt gatgtaatat
    15721 atgaagatga agttaataca tataattcaa cactatactt gttatctagt gattatagtg
    15781 ttactgtaat ttctaaaaat gaagaaactg agtacttact taaataagca tatacattga
    15841 taaggtgtat atgcttattt taattttaat aaataaagga gaaaagcaga atgaataaaa
    15901 agagaactcc tgccaagaga gttgatatag ttttacttaa attagtaaaa gaacgtagtg
    15961 ttctatatga aactagaaaa ataagtaatc tttatgatgc ttatagatta gcaaagaatt
    16021 ttttataaat agtgctagag aaaagtttgt agtggtatgt ttagatacaa agaattggcc
    16081 agtagcatag aggttgtaag tataggcact gtaaatttat ctatggtata tccaagagaa
    16141 atatttaaag tagctatatt aaccaattca tctgaaatga tatgctttca caatcaccca
    16201 atgggtaata ctgactttag caaggaagat agttataact aatatgctac agaagcgtgg
    16261 agaaatatta tgcattgaat tagtagatac atatagttat tgtagatgag gataaatact
    16321 ttagctttaa agaaaactgt aggatataag agtcttagct taaataaatt aggctaaggc
    16381 tttttctatg ttccaaaaca attaaaaata aatcaaattt aggttaagcc cggaaagccc
    16441 ttgaaaaaaa taatacatat aaatttaaaa ctaaatagga gttgtaacat gtttaaaaaa
    16501 gaaaataggt atatgacaaa agagatagct gaaaatctac caattgaaat agctatacta
    16561 ctatggaatt taatagatga cttaactaca gaaaaagatt atctacaact atttgaaata
    16621 aatcctatag gattaggagt agttgagata gttcataagc aagaagtacc tgaatatgaa
    16681 gctaggatat atatacagaa tgataaaatt aaagataaat taaaaatata tgttatagat
    16741 aatgttgaat atagaacaat gatgttttca aatgaatatt agttaatgat taaaggagag
    16801 agagtaatat gataaataat aaatctgaaa taattaataa gttatttttc aatgaattaa
    16861 aagagttaat agataaatac aacaatatag atgataaaac tgtagatgta atagaaaaga
    16921 tatttacatg tatagaagat gaagaaataa agaattacct aataagagat aattgtaagc
    16981 tacaagagct agtaaataca tacaataaac ttgaagattt aaacatagat gaagctatat
    17041 tctttgcttg gtacaactta actataaata caatatctat agataaagca agtgagtact
    17101 acgatgattt aactacaagt aactatatag aagtagaaaa tcatataata tatacaaatg
    17161 aaagagattt aaggaagtat gctgaagatg aattagaaac tatgttaagc atggaacatc
    17221 atatagatag attactacat aaagacatgt taatagatat gtggttaaac aatacttcaa
    17281 aagaagaagt aatagaagaa atattaatga gtgatgatat agaagatata ttgaatttat
    17341 ctccagaata tgcatttaca ttagctaatg gaatagaata tagatactca gaaaaagaag
    17401 aataaaataa gtatatgtac tgaaaaatac gggctttaag ggcttataca ttaaagtaca
    17461 tatttgaaaa taccatagat tttacaagag aaaatcagaa tgaaactttt tcaaatacta
    17521 gttattatta attagtgcta gaaaaggagg tggagtgatg actaacaaca ataataattg
    17581 tgattataag ggcatatatg cagatatggt tgaggttttg ggtgaagaaa tagtcattaa
    17641 attacataag tattatcgtg gacaacaaat aacatttcca atgaaactat attctattga
    17701 atatgtggaa cgatatatag tgaagaatta tagaacaaaa acaataaaag aaatgtgtag
    17761 agagttagga tatacagagg gatggataaa gcaattaatt aataaaaata gattaaattc
    17821 aaagtaatta gagaaggaga ttgacagtag atatgatatt aacagtatta gcaatactta
    17881 tggggacagg tatatttttt ctgattaatt caatgctaga tataacgtat tttggatgtg
    17941 gcccaatagg atttttatgg tttggatgtt ttattgtgtc atatgcaata ttaacatcat
    18001 taggtggtat agttttagga ttgttaaagt ggatagtaat aggattgatt atactatttg
    18061 taataggatt aatagcgaat aagataaatg attaaattac tgtagattat tttgataaaa
    18121 taattattta atatattgag gcattacatg atagaagaat aaatataaat gacttaaaat
    18181 ctttaactta actaaacaaa aaatatatta tttattacaa aaaatgacaa aaaaattaaa
    18241 tattatattg tattatgaca atataaaaca ttggagttta taaattagga ggaatatttt
    18301 atgcaagatt ttgattttat aagtgagaca ataaagaaat ttcaatccga tttagaaaac
    18361 atggataagg taaatatact tgttgtaggt aaaacaggag taggtaaaag tacattaata
    18421 aataatatat ttagagaaga attagcagaa actggaattg gtagacctgt aacacaacac
    18481 ttgaaaaaaa taagcaaaga aggattacca ataaatttat acgatacaaa gggattagag
    18541 ttagaagaag atgtgcaaga gactataaaa aaagagatat tagatgaaat agaaaattgt
    18601 aatagaaatt cattagaaag aaatgataaa agtgagttaa tgcatgtatg ttggtattgt
    18661 ataaatacat cagtagctag atgtgaagaa actgatataa aatggataaa tgagttaagt
    18721 gaaaagatac cagtaatagt tgtattgaca caaggattcc caagaaaaaa agcaagagaa
    18781 ttaaaatcta gtattgatga tttaaattta aactgtaaga atgtaattcc agttttggca
    18841 gagcaactag tagaagaaga ggatgagata gttataaagt catatggttt agataaatta
    18901 gtagaagtta catatcaagt aataccaaaa gaggtcaaga aagcttttgt taatgtacaa
    18961 aaggtagata taaaaaaaaa ggttgaagag tcgagaaaat gggttttagg atatgtagga
    19021 ggatcaggag caataggatt ttcaccaata ccattttcag atgctccatt attagcaacc
    19081 gcacaagttg ctatgatatc tcatataaca gtaatatttg ggttacaagt tgataaagct
    19141 ttactaacgg caattgtaag ttctatagga ggggttacat cagctacttt actaggaaaa
    19201 acattggtat cgaatatact taagtttata ccaggagctg gaactatagc aggtggagcg
    19261 ataagtggtt ctgtagcggc attaacaact acagcattag gaatggcata tataagtgta
    19321 ttagaatata tactaaatga gaatatgaaa ggtaatgagg ttaataatac tgaaatagct
    19381 gaaaaaatga aagatgcata caaagatcaa ttaggaatgt tatctaagaa ataattaatt
    19441 caagataaag tataagatta attataggga aaaagtaaaa tttaaaggta tatttggtaa
    19501 aacataaaca aaaatgataa tggcgtcaat attatttgtt gtcatatgta gtagcttagt
    19561 atatatatta ttgagtgata ggtttaatca taagttaatt tacttagaga aagatatatt
    19621 agatttaaga aataaaaatt tgtaactagc taataaagga tcagtataga aacagataaa
    19681 caagaggata atgtagatat taaatctaaa aacactaata atgaagaata taaaacttca
    19741 aaactattta ggcactagat agagtatttg ctataatgaa taagctaata gagaaattaa
    19801 aacgtttata gtaagataac taattcaaat acatttagtg gacttcaagg aacatttgat
    19861 acactatcaa actatggtag ccaattgata gaccaatcat ctaaattgaa tttatcaaat
    19921 gttggatggt tagaaatatc tgatataatt acaagtatag gaaaggacta ttagattctg
    19981 aaaatatgtc atttgaagca ttaaatataa tgggaaaaat aggaaaattt ataaattata
    20041 ttgaaattaa ttatattaac taattaaata ttgatacata atgccttgct acagttaaat
    20101 gtggcaaggc attatttttg taaagaaagg aagaattaac atggcgaagc aaagtaaaga
    20161 ggaactattt gaaaaagaaa ctaaatattg caagataata agaagtgtaa cagtagaaga
    20221 tggagatgaa agatttgcaa tagagaaaat atatattaag tcattacaaa gatacgaggt
    20281 tagaatatgc ctgtatcgtg actgccgaga tagaattaat aaacttattc caaggcctgt
    20341 agatttaact atggataagt ttgtagcatt aatactggta ggattaaagg ctggtgtact
    20401 agatgatgat ttcaagcaag aactaattaa aggtttagct taggaggtag aatatgacaa
    20461 tagaagagtt tactagtgga gtaatgtttg ggatttcaat ttttagtgca gtattaaagc
    20521 aagtattaga aaataaaaaa tagtatacag gaggtatgag tatgattgga tttataatag
    20581 gaagtataat aggaattgga ctatgtatta gtatagagat actgatatcg aaaaatgcca
    20641 taatatacta agttatattt aaattattaa tagattcata tataatttat ttaagccctt
    20701 aaagcccaga taagttatat taaagtaaag tttgtattta tgtaaattaa ataatatata
    20761 ttattataaa tttgaaagga ctttataaat atgaaaggca atataaacaa aaaagatata
    20821 gatttaagta aaataacatt tgataagttt ttagaagatg aaggattaca aaatagagag
    20881 agagattact tatatgtaga tgattatgac aatactttag atactcaaga atttaaatta
    20941 catataattg aagagaatac tgataacaca tatatagata aagataaata ctggtattta
    21001 gatttagatg atagtttatt tgaatacgaa gaagatgaag atactattgc taaaacatta
    21061 tatagtctaa tagatattag aattaaattt ttgaaacatg ttgagtatag aaaatatata
    21121 aatctaggag taatagacga agaatatttt gatgagatta aatcattttt gaaattttat
    21181 atagtagcaa aaacaaagaa aaatgagcta ggtaattcaa atttaaagca gatggctata
    21241 gatatttttg ataaagaaag gtttgaagac gacatatcag atgatgatat ggaaaatata
    21301 agtgaatgga taggagaaga tcaaaacttt aaaatgtttt atgataaagt ttgtagggat
    21361 ctctcaaatt ctacacagga taaagaaata ttaaaattag caggaatcag gaataataaa
    21421 gtaaaacatt acaaaggaag aaaaattagt agaaaatgta aattagaact taaatcattg
    21481 actaaaatgt gggagtatga aactaaactg actcatgatg caaataaggc acataagaaa
    21541 ataaaatcta atatgcttga aaaaatgaca gataagaatt ataaaaatat atatgaatat
    21601 ttaaataatg agattataaa tagtaatgaa gaatataaaa atatttattt ttatagctta
    21661 gaattaaagt tagcgaatga attaagaaag tgtactctta aaaacttaaa taaaattaaa
    21721 gacatagaaa atcaagtaaa atttatttct tatactattg cttatataca catagttcca
    21781 gttttaacga taagagagaa actaagcgat aagttattta atatattgtc aactaatgaa
    21841 ggtaaggata tagaaaaatt tactaaagaa gttagtctta taatgagaat tataaatata
    21901 gaatgtttgg agttattaaa tatagttagt aagaacaact attataaaaa ttttagtgaa
    21961 aaggaattag aggagtttaa atctatttat aatataaata atggaagaaa gtcatttgaa
    22021 aataaatata aaataaaagt agattataat atagatgatg taagaaagta tggagaggtt
    22081 ataaaagcaa taaatataga aagtaagaag aaaattgtag atagaattaa gaagaagaga
    22141 aaatctaatt agattttctc tatttttttt gaaaaaaata aaaaatattt ggtgaaaacg
    22201 tttatcttta ggtgatatga gtagtcatta tttattatat aatcatattt gtaggaacga
    22261 gctaattaat aaaatctaag aacaatagct taatgatgaa aaagtacggc ctttcgggct
    22321 ttgacaacag gaggtatatt aatgacaaac tttaaaagtg taaaggtaga attaattcta
    22381 cttattgaat gtgaagaagg aaatcgtaat gaattagaag gtatgattga tgaaggtgta
    22441 ttaaatgaaa aagaatatag tttaactata ttaggtagta cagagtatga agataacgca
    22501 agggctattt acatacttat gaatacagga ggatcatacg aaaaaaactt acaacgatta
    22561 agtagattac acttgaaaat tgaaaactta cttaaagata caaatgttaa atatagaggt
    22621 atatctttag taccgaatat tgttaaatgg gataaatagg aggaatacaa atgagcaagg
    22681 caataaacag agaagaatta attaaattat atgaggaaat aggattaaat gttttagata
    22741 ataacaccgt tatgaattca tctaataaaa agatatgtaa ttttttagta aatataatag
    22801 aacaaagggt tatagatgga aaaatgtatt tatgtataaa tgctatgggg attaatggag
    22861 agctattatc agaggtaata ttagattcga ataccataaa tagaactaca tgggtgattg
    22921 aaaattgggg ttttaaatat tctatagata aaaaatatat taatgacttt attgaattga
    22981 tacaacactt atgtatgaat ataaaaacta agtatatata tgaccataca ggatggatat
    23041 atcaagacaa taagtggata tatctacatg gaggaggagt tataggaggt tcagatgttc
    23101 aagttgagtt agatgaatca atagataact atatactacc agataaaatt agtgacataa
    23161 ataaagcatg tgaaatgagt ttaaagctag tagacttaat agaagatgat aaaggtatta
    23221 tattctcttc attagtttac ctatctccac ttattgaaat tatcagtaga aaaattaaac
    23281 caccggaaaa tatagtatgg acatatggaa aaacaggatc aagaaaaaca gcagtatcaa
    23341 aagttgtatt aagtcatttt ggtgatttta ataaaaaaat tccagctaca tttaatgata
    23401 cgattacagc tattgaatta aaagctaata agttaaagga tagcttatac ttatgtgatg
    23461 actttgcacc taaacaagac tttagggata aaaaaattca agactcaaag gcagaatcca
    23521 ttataagaat gtatggagat agagtaggga aaggacgctc aagtaataag ttagatataa
    23581 aggatgctaa gagacctaga ggaatgatat taataacagg tgaagatgtg atatgtggag
    23641 aatcatctaa tgctagatta ttatcaatag aattaaatag aagttcagta gatttaaata
    23701 tactaactga attacagaat aatagtcatt tgcttggaga agcaatgaga ggatatatag
    23761 aatggttatt atctgaaatg ggaaatattg atgaattatc taatatatta ttatataact
    23821 ttaaatctta cagggatgaa attagagaac aatataaaga tgatatacat ggaagaacta
    23881 ttgagtctag tgcatggata ttagtaggtt ttagttgtat gttaaattat attagagata
    23941 aaggtgttat agataagtat gaagatgatg agtacatgga tagagcgatt aaagttgtag
    24001 aaagattaat agaagagcag ataaaattaa tatcgagaaa ctcacctata gatatatttt
    24061 taaatacatt aaaggaatca ataaattcaa agtcaataag aatagcaaca ttaaatgacc
    24121 agaaccaagt tatagaagat aaattagaat atatatgtgg atataaggat aaggaatatt
    24181 attactttta cacagataaa gtatattctt ttatagaatt tgaaaataaa aaaagaggta
    24241 tacatttggg aataagtcaa agacaactag tgaaacagtt aagagatagt ggaattgtga
    24301 aagttgattc taacaatgat tctcctaaaa aaactattca tacaaaagat gctagcgatt
    24361 caacaggata tacaacaata agaccaagaa tgcttcagat agaaagaagt ataattgaga
    24421 actttcaaat ataacttata atcaagagtg cttatgtact cttgattata ttctatgata
    24481 aatggaggat ataaatatga cagaaactta taaaatcagc ataggaagaa aagatttata
    24541 ttctaaagac tataaggtag ttgaaagaac tgactatgaa aagagacaca cagttaatat
    24601 aagtagaagc ttagtagaca tactttctat acttgtaaaa gaagatagat agattaaaat
    24661 atggttacac acttagtgtt agtgtgtagc ctttaatata gattaaaatt agtatattta
    24721 aactttggag gaaataatat gacaggaaag aaagcagtag tatatgcacg ctttagttca
    24781 gataatcaaa gggacgaatc aatagatgct caattaagag caataaatga atatgcagat
    24841 aagaataata taaaaatagt taatcaattt atagacagag caaaatcagc aacatcagat
    24901 aaaaggccag agtttcaaaa tatgattaaa ttctgtgaag cagatacaac aggaatatct
    24961 atggtaatag ttcataagct agatagattt tctagagata agtatgattc agctatgtac
    25021 aaacagaaat taaaagtaaa aggaataaga gttgtaagtg tattagagaa cttagataat
    25081 tcgcctgaat ccctaatatt agaatcagtt atagagggaa tggcacaata ttacagtgct
    25141 aatttagcga gggaagttgc taaaggtcag aaagaaaatg cccttaaagc ccttcataat
    25201 ggaggcgatg caccattagg ttatgatgta gcacatgata aaacatatac agttaatgaa
    25261 gaagaagctc aagcagtaaa gattatattt gatagatata ttaaaggata ttcatatagt
    25321 aagataatag atgaactaaa tatcttagga tataagacta aaagaggtaa taaatttggt
    25381 aagaatagct tacatggaat attaaataat gagaaatata caggagtata tgtatttaat
    25441 aagactcaga gaaaaggtgt agatggaaaa agaaatggac ataagcaaaa gagtgaagag
    25501 gaaataataa aaatagaagg tggtatgcca caaataatag acaaaggagt atttaaacaa
    25561 gcacaagata tgattcaaaa aagaaagaaa actccaggtg cacataaagc tactactaca
    25621 tatctattaa caggactaat taaatgtggt gaatgtggac atgcatttca ggggaataag
    25681 agaaaagatt cttatggaaa tgaatatgtt tcatatagat gtggatgtag aaagcaaaag
    25741 agagaatgta ataatagaga gataaaaaga gactatttag aagagtttat attacaagaa
    25801 cttgaaaaga acatattaaa tgatgaagct ataccgattt taagtaaagc attgaatgag
    25861 aagctgaatg ataagaatga aagtaatgca gagctactta aaaatctaga gcagaaacta
    25921 gataaggtaa ataaagagat aagtaatata ctaaatgcta taatgaatgg tatagtaaat
    25981 agcatgttaa aagataagct tgatgagcta gaacaagtaa agttcaactt agatttaaaa
    26041 atgaatgaac taaagataga aaataaagtt gtagatggtg taggtgtaac agaagatcaa
    26101 ataagaggta tgttttcaag atttaaggaa tttgtactag agagaaatat acctgaatgt
    26161 aagaagttta taggagacta tataaaggaa gtaatcgtat ataaagacca cattgaagtc
    26221 atattcaatg tggtcttttg ttttgttgac aatgatataa ctcatgattt acatattatc
    26281 acagaaaggg gtaaaattac atagtaaata tatattttat aaaagtaaat atcagatatt
    26341 atttagataa aaattatttt tgaaaatatt agttttaaaa aatatattta tataattata
    26401 aaataaaatg gtataataaa actttaaata tgataaagag gtgagactat tggcagatat
    26461 atttacagta ctaaattatc aaggtagtaa aaagagatta ttagatttta tatatgaaaa
    26521 tacacaagaa tatattgatt ctgataaagc ttttttagat atatgctcag gaacgagtgc
    26581 agtagcttat aatatgaaaa gacactttac ggtttataca aatgatagtg aaaattatgc
    26641 atatcagata tctaattcaa ttgttaagaa taatgaaaga tataacttta gtcaatcaga
    26701 tgaaatgatc ataagagaaa aatataatat taatttacaa agattaaata atatttttaa
    26761 cgatatggta aatcaggaag atatgttatt agaacaagaa gatgcagacg gtttaataga
    26821 gctatattca aattgcccat gtatatggaa aaataatgtt gatattgaaa tagaaggcaa
    26881 tacaatacag agtatatatg atttaagaaa atgtaaacga gacataccga atgtgttatt
    26941 cacattgtat tattcaagta gttacttcgg cataaagcag tctatggaga tagattctat
    27001 tagatatgct attgaattta tagaaagtga aataacaaag agcattcttt ttacaagttt
    27061 atttttcgca atgaaagagt gtgtttttgc taaagatggt cacatggcac agccattaaa
    27121 tatggaaaca ggcaagaaaa gaatgttaag attaaaagca agaagtatat atgacatatt
    27181 tatagataaa ttaaaggaat ttaatactga ggagtttgta ttatcacaaa aggagaataa
    27241 gtgcttcaat aaagacttta gaacattatt agaaacagaa gaaagtataa aagatgaagt
    27301 tggttttata tatatagacc ctccgtatac agatatgcaa tactcaagat attatcatat
    27361 tcttaataca gttgttttgt atgattaccc agaaatatca ttgagtagag gaactatatc
    27421 aaaagggata tatagagaag gtagatatca atcacctctt agtcaaagaa aacatgcatt
    27481 aaatgagatt gatttcttat ttagtttctg taaggaaaat aaaataaatg tagcattaag
    27541 ttatgcatat ccaatagata cagaaaaaca agcaactaat agatatacgg ctagtattga
    27601 tgatttgata aatgtagcca aaaaacattt tggagataat gttaaggtag tacatgaaga
    27661 atatagtcat gcaaataata gaaatagtga taaaaagaat gtacttgaat atttaataat
    27721 gggtatacac aataaggagt aaatatggat aaaattaata aattaaaaga gaggatagct
    27781 aatatagaag cgacgaataa aaatgatata tattcttcta acttatattg gtcacaaaaa
    27841 ccattcaata tatgtgatga aattattgaa catttaagtg aagatggaga tataatattt
    27901 gatccgttta tgggatctgg ggttacagtt atagaggctt tgaaaaaaga gtataaaaga
    27961 aatgctattg ggtgtgatat aaatgatgca ccaatattta tagtaaaaac attattagaa
    28021 aaatataatg tgcctaaaat agagaaagat attaaagagc taaataataa attaagtaaa
    28081 ttatcaactt actattcaac aaaatgtcgt gaatgtggag aagtagttac tatatcgaaa
    28141 actatattcg ataaggagaa taggaatgca aagtgtgagc taaagtctat acattataaa
    28201 tgtaaggaat gtaaaaatga ctttaaaggt gaaccaaatg aaactgaaat atctaaattc
    28261 tttattgatg aagaattaaa gaatatagat gattttcaat tcatagccaa ttcaaggctt
    28321 gcagttggcg aaggtgatac agtaagaact attttttcaa atagaaattt aatagtatta
    28381 gataaaatat taggacatat agatgaatat aaaaatagtg aatcttatga gcctatgaag
    28441 tatattttat tatctatttt acatttaagt aagattacag atacacattc taattctcag
    28501 tggcctttat ggattcctaa aaaagactgt gttgaaaaaa atgtagtaga attattcata
    28561 aagaatagta agaaaaccat taaggcatta aaactagcat ctaaatattt atgtgaaaat
    28621 agagaaaatg tagaactaat caaaaatcta gatagaggga aatttaaatt gataaaagat
    28681 ggagttcaaa atatagaaga tgatgttata cctaatgaat ttgtggactt gataataaca
    28741 gatccaccat atatgggaca agttttatat tcagagtata tgcagttata taaacctttt
    28801 atggatttgg aattcgaatt agaaaatgaa atagttatat caagtgcccc agctagagat
    28861 aaagggaaag tattatattt tgatatgatg aattctgcat ttgaaaatat atctagagta
    28921 ttaaaggtag gtaaatatat gtgtatgtac ttccatgata gtaatctaga tgtatgggat
    28981 aatataatag atataatgac caataataat ttgaaataca tgggacaaat tcatgtaagt
    29041 aagaataaaa acactcttaa aaacatactt agtcctaaga agtcgttaaa tggagattgt
    29101 ataattttct ttaagaaaga tttaaatata aactatgata taaatgaagt agataatata
    29161 gaagataaga taaataatat tgcacaagct attatagata taaaaggata cgcatcaact
    29221 ccagagttat atgataatgg agcactagag tatataatat caaacggaaa actaaaagag
    29281 atttctaaaa agtataagga tttaacaagt atatttgagc aaagatttaa ttgggataag
    29341 gaaagagggg tatggactgt ataataaata aaaagcatct atagataatt atagatgctt
    29401 tttatttata ttttatagta aactaaatat ttaataattt ctaattttta tacaatatgt
    29461 taaaggattg gctatccaaa gatattattt aatataattt tttagcatta actctagtta
    29521 aatcactttt agataatgaa acctgtaatc ttctgatagg agaacccttt tctaaacatc
    29581 tattgatctt ttcctgtaac ttcttacgaa gaagaggaac tacatctgct ggttcagttg
    29641 agtagatatg ttcaacttct atattttctt tatcaacaac tgctaatatt atagctttat
    29701 cattataata tttatttagt acattatcag atatatcttg aaagttccaa gcatgatttt
    29761 tagaaacttt atattcataa ggattacctt cactatcata ggcatcatga gcaccttctc
    29821 gtccaccttg ctctgggttt acttgatggt ttaattctaa tgcaactatt aattcccaaa
    29881 acttattact tgtaagtaaa tttttaactc ctgttaattc ttcaagttca cttgaagctt
    29941 tataaatagc acttagatat ttatcataaa caccattttg agctgatggg attatcttac
    30001 ttgcatttaa tctagactct agttgattag ggctgacatt tatcattttt ctggaatttt
    30061 gtatactttg agtatacttt agtaaatatt cacacattat atctccaggt atagagtaat
    30121 accaatcaag ctttccaggg taaggaaaat caacatcatt tatatgagca aatataactg
    30181 ccttagcttt ctttaatttt gctatacttg tatccgaaaa atcattaaac gtccaagaat
    30241 ggttagagct acttttcttg aaatgtttat attcaaactc atttccgaat tcatcttttg
    30301 catctctaga accactatgt ccaggtatta gtatgtgatt aagtgaatta gcagtcataa
    30361 cttcatatat tttgctatta gaaagtatat catttacttt atattcttta aaaataccat
    30421 cttgtatagc ctttagttca tttattttct gtgttattaa aacatttgtt atattatctc
    30481 ttatcatatt atcatagctc cttaataaat tagtattttt agataagtca tttttaatta
    30541 gatttatcac ataactattg atgctatcat ttttaaatgc tactaaatcc aataaatctt
    30601 tatgaaaatc atccttgagt cttatagtta gttttttcaa gctatcacct cggatattaa
    30661 ttagatgtgc cgtcgagata agtataatta agcaggttta taaagtcaag gattaaaaaa
    30721 attaaattat agatatataa aagtatatat agcaatatag ataaatagct aaactattaa
    30781 tcgtgggtat tattcttgcg attcgtctcc accaattttg aaaaaagaat gatgaaatac
    30841 ttggaaatac tagtctttgt tgactagtat tttttatttt ggagaagaaa tccaccaacc
    30901 gtaccccaac cacagaaaat gaggtttttt tgggggtata ttggggtgca tttaggctgt
    30961 ataaaaagtt tttatttgtt tattatttta tttgtttatt attttatttg tttattatga
    31021 taataggtaa catagaattt taatatctac tttatgatat aatattttta taaatgtaag
    31081 acagtttaag ttgttaatta gtaaaaatat atattatata agcttgatag gagttgaggt
    31141 ttgtaatgga tgaaagaaaa ctagaatttt ctattttttg cattgaagct ttagcagaaa
    31201 aattgaatat agattcagaa ggagtttata aacttcttaa acatgatact gatattttag
    31261 ataactatat aataccttgc tatgaagcac tacattctca aagtaaaggt tacatagtgg
    31321 aagatttaat gcaagtactt aaagaaaagg gtgtgatata atgattgtat atcatggttc
    31381 atattgtgtg gtaaagacgc ctagtattac cttttcaaga gattctttag attttggaaa
    31441 aggattctat gtaaccagta taaagacaca agcaattaac tggacagagc gttttaaaaa
    31501 aagaggtaaa aaagcatatt taaatagtta ttctttagat attgataaat taaaagaaaa
    31561 ctgcaaggta aaaatcttcg atagttataa tttagaatgg cttgatttta taatagaatg
    31621 tagaaatatg agtgatatat atatgaaata tgacattata ataggtggta ttgctgatga
    31681 taagatttac aatacaatag aactgtatca agataatctt attgaaaaag atgaagcttt
    31741 aaaaagatta aaatactata aaccaaatga acaaatatgt ataaccaatc aaaatgtaat
    31801 agataaatat ttaaagttta ggtatgaaga ggaggtataa tgattatgga agcaaataaa
    31861 acattattac aaatactata taaaaaaatc atattagaat tttccaaaca aacaggtaag
    31921 agcttggaag aaagtatgga ttatttatat acttctgaaa catataaact tataagtgag
    31981 ggtgtatcag atatgcactg taagggtcat atatacttgg ctcaagaatt aatgttagaa
    32041 aatggattaa tgtaccataa gggctatcca agataaataa ttaaaactag atacgaaata
    32101 aggatacaat ataatataaa attaatttgt atccttattt tgattttgta attaactata
    32161 tgaaatcaca atatttatat gtatttgatt tttacaatga aaatatttta tccaactttt
    32221 ctacagcttc aactttctta tcttccataa cttgagtata tatattcaaa gttattgata
    32281 tatcataatg acccattaaa acttgtacag ttttaggagg aacatcattc tcaaaaagtc
    32341 tagtagcata agttttccta agaccatgaa actttatagg ctctatattt aagctattta
    32401 atatagactt taaattcctt aaaggtcttt tatcatctat agggatgcct aattcattgc
    32461 aaaatacata attattattt atatataatt ctccagcctt taatatatct gtattttgat
    32521 ttactttatg ctctttcaat ttatttaaaa catcttttgg aataggtaca gttctgtaag
    32581 aatttgatgt ctttggccct tgctctaata ctttaagctc tctatttcca gttttatcta
    32641 taaaatatgt tctttgaaga gttcttttaa ctgttaaatt agacttttta aaatcaatat
    32701 caaaccattt aagtcctaat aattctccta atctaagtcc agtaccaaga gcaagtaaaa
    32761 ataatacctc taatttatgc ccatctatag cttttataaa actcttttgt tgttcaagag
    32821 tcaatatttc aagtttgttt tcttttttct caactggtat atttaccata gtacaatagt
    32881 tacgttgtat aagaccttgt ttttcagctt ctgataagca ggttttcagt ttagtgttta
    32941 tttgccttat agtaggtata cttttattgg aatcaagcaa tctattgtaa tatttttgta
    33001 tgtgagatac tcttaagtac tttaatttaa cattgcctaa atcagtatct ttaatataat
    33061 tacgatagat gctttcatat ctttcaaatg acttgggttt taaatctttt attctatatt
    33121 caaataacca attgtaaaac caatgctcta aagttatttt atcatctgaa atatcagagc
    33181 ttaaataata ttgtttttta taagcatcta atttatcttt aacttccttt tgagtcttac
    33241 cataaaattc ttttctcagt ggtttaccat cttcattata gccaatcatt atacgggaac
    33301 gccaaccatc tttatatttt ccgatagagc cttctccatt agctctttta gttgccattt
    33361 ttaaacagct ccttatatga tttatagtta tatccatcaa agaatgtaat acatttctct
    33421 aataagaatt ttataacttc atcagcttct agtgtttcat agaagtttag cattaatgtg
    33481 ttgtactctt gtttatgttt agctggtatt gatagaactc ctatatcatt atttataagt
    33541 attaggtttg aggtaagtct agcagttctt ttgttgccat catagaagaa ttggcaatag
    33601 gacaaccata aatttattat tatagccttt tctaatgggt tagttatttt atttatgata
    33661 tttatgtcat ttacaaataa atcatttaat agagtggctt ctatgcattc atattgagta
    33721 gtaccagcta tacctatatt accatttctg aaatctccaa cgattagagc ttcatctttt
    33781 gcaactattt tatgtataga gcaaattgta tctttattta aagataagtt ttctttgtta
    33841 cttaatttta ttacataatc ccatgatgat tttatattta gtatttgatt ttggtcactt
    33901 aatttatgtc cgcctacggt tataccatca agtaatgttt gtacttctgg gaatgtgaag
    33961 gggttatttt ctaggttacc catatcatat acaaattcac ttatcattct tctaatgtat
    34021 gttaaagtat attttttatc tccatgaggt atattagtag ggaatttatg tgtgtatttt
    34081 ggtatatatg atttattcat gattttagct cctttcatat ctaattttta tttattaact
    34141 atgaatgtat aaaagttaat aggtaaactc atattttgaa aatgtgcaat actaatattc
    34201 ttcatcctca tcttcaataa gaccattaga gttttcttgt ataaaatttt caacaagacc
    34261 atttatcacc caatttagat ttttggagaa gtctttgaag tcagagaagt ttaggttaat
    34321 tggttttatt gtatctgcat tatctgtaat ttcaaacttt tttttatagt ctgtttttat
    34381 atcataacca taattttcta atatgtgaat tactaaatcc aactctttat caaatacttt
    34441 taaattaata ttattatttg ttaaagtatc taaatcattt tcttcaacaa tgagtttatt
    34501 tatagcaatt gataaagcag tagctatttt tcttatcata tctaaactag gcattctttg
    34561 attttgctca tatttagcta tagcatgaac tgaacaacca atcttgttgg ctagctcatc
    34621 ccttgacata tttatcgatt ttctatattg tttaatcttt tctccaattg tattattcat
    34681 cataatttca ccttaaatat atcatcaaac aatgattgta cttctaaaca tgtaaaggag
    34741 ttattttcta gattatccca tatcatatac taaattactc ataactctct tagtgtatgt
    34801 tagagtatat tttttatctc catgaaataa attagtaggg gatttatatg tgtattttag
    34861 catatatgat ttattcataa ttgtaactcc attcatagtt ttttatcatt gctttagata
    34921 gtattgatat tattttatat tttagttagt agttttttta tttctttaag tgtattttca
    34981 agcttttcat ttttttcctt tagttcgtta ttttcttgta ataatttaaa gtaatcatta
    35041 tttttaatag taatattttc tttttgagat attaattttt ttagtcgaat attacttcca
    35101 ttatctgttg agtcactaaa gtaatcatag attgtttcta tactttcttc tgatagacca
    35161 atatctaata attcatcaat tgattgtttt gtaagaacat catttttaat aatttctttt
    35221 atgtcatcag gatgtaatga aaaatctaat tcagtattag atatacaatc tgaaagtatc
    35281 caattataaa cttgattttc atttagttct aatttttcac caagtttata atattggtct
    35341 ttatcagacc aggcacctag caataaactt gaggtaattc taatatcatc ttccataaga
    35401 tttgaaatag catttaaaaa ttcatcaaaa gaatagtatt cttctgggaa taaagactgt
    35461 aaaaggtata aaacatcttc attagtcatt acttcatttt caatatcaaa ataaaagata
    35521 gtcttttcaa ttttcaaagc tttagcgagt tttgataagg tatctatact aggtattctt
    35581 ttatcatttt cataatttat tagagcattt cttgagatgc cactaatttc agcaagttga
    35641 atctgcgtta gctctttttg ttttcttatc ttttttaagt tttttccaat ttgcaatatt
    35701 atcacctcgt ataaagtata tcccaaaagt acacaaatga gaacagaaaa ataatatatt
    35761 cttattaaca gtacacatat atcgacatta taattaaaat gtaaagttta cgaatgtaaa
    35821 ctagaaaaaa ggaggaaaaa gtatgggaat caatttaaaa atatttagga ttaaaaaagg
    35881 tctaaagcaa caagaactgg cagatagagt tggtatatca agatattatt tatcaaactt
    35941 ggaaacaggt aaggctaata atccaagcaa tgatttgatg attaaactat ctagagcttt
    36001 agatacaaca gtagaagaat tattttttag taaggaggat taaaatatga aagagaataa
    36061 taatttagag gttttaaaga cattacaagc cactttaaac attattgtaa agaatgaaga
    36121 agaagcacaa gaaaaaaagc aaggatataa aattattgaa aatgcgaaaa gaaataaagc
    36181 tgagcttata acatgtaaag aagcatctaa gctttatcct ataggagaat caaaatttag
    36241 gcagttatgt cattctaaaa acaaaggatt cccttgtata tggataaata atcgagtata
    36301 cataataaaa aataaattag atgattggtt tattgaaaat gcaaatggta tcaagttata
    36361 gtcttaaagt aggtgtttgc aattgagcaa taaagggtgg ataaagcttt atagggagtt
    36421 gttggataaa tcaatttgga aagatattaa accagaaaga aaggtaatat taataactct
    36481 attacttatg gctagtcata aagaaaatca tgtttttata gataataaaa agataaaaat
    36541 aaagtttgga caatttattt cttcatatag caaaatagct gaaagatgtg gtaaaggagt
    36601 tagttatcaa atggttagaa gttgtttgtt ggtttttaaa aatgctggtt ttctaacata
    36661 cgaaacaaca aacaagtata tagtaataac tattgaaaac tgggagcttt atcaagagaa
    36721 tatagaaaat caacaaccta atcaacagac tattaacaat cagtcaacaa caatcaagaa
    36781 tataaagaat gaaaataata ttatatatag tgaaatcata agcaaattta actcaacttg
    36841 tattgaactt tcaaaggtca agaaactaac agatacaaga aagaggagaa taaattcaag
    36901 aataaaagaa tatgataaag aaactgtatt agaggttata aatatagtta gtaaaacaag
    36961 ttttctgaat ggaaataata atacaggatg gaaagcaaat tttgattgga taatgaattc
    37021 aagtaatttt actaagatac tagagggaaa ttataatagc aaggaaattg tcataaataa
    37081 agagacagga atatataatc cagatgactc acaattaaag tggtaaggag gttatattat
    37141 aaataattca aacaacttaa ttaaaaatac agaagcagag caatcaatta aattacacta
    37201 agttagttat aaatctttca tatatttgtt ttttaagtat ctctaatatc gtttaaatta
    37261 cactaagtta gttgcagata taccagaaaa tatatataaa attatgcgta aactatattg
    37321 ttatgagtac aaataatatt tacctattca ttaaaaaact taactaagaa tttaatttat
    37381 attattgaag tatcaataat tttggaaagt agaaaattat accccaataa taccccaact
    37441 acaaaaatag acaataaaaa ataaccagaa aaattgcttc aacatcatga ccaaatagcc
    37501 atatacctat acttataaaa accaacaaaa caatcaaata accacttata aattctcctc
    37561 ggtctccacc attggaatcc acgaaaacat attgatttaa tagttaatat gttttttatt
    37621 ttgaaaaatc atatataata taaattaata gtttatttaa aaatttcagt atgagcacaa
    37681 aattatataa ttattgggaa ttagttataa taagtaattt ctagtaagaa tgatttgcaa
    37741 aaaataataa tttaaataca aaaaactaaa ggatagaagt cataaaatta acttttaacc
    37801 tttagttata taaataaaaa attagttatt actaaattaa aattagattt ttaaagaacc
    37861 caatatctct attatccata tcaccaatta acatgcttct atcaagtaat aaattatact
    37921 cctcacagct agtttcaggc aataaagtac atgaatggca tgctcctaga tttaaagaat
    37981 ttctaccttg accagtacta tcaatacata ttgggtcatt agaacaccaa agagcacgat
    38041 taagagcact atttaatata gatggtaatg aatcatgcat accttgccta actaatcctc
    38101 ctaaagtacc ttcagagtca ccacttgcag tgtaaactaa aattccagac ataacttttt
    38161 cattttcgga attattacaa tatatacgtt ccctaagtga agaggtagca tatccacaaa
    38221 caaaactaag ttctcttata attaaatgag ctaaagtatg tagtaataag aatttaggtg
    38281 taatttttct ataagctttg tcattaacat taatatcttt attatatcta gaatttaaaa
    38341 tagatgcatt atcctgtatt ttaggattag atgaaatcca gctttttacc atatcattat
    38401 ttatctctat gaaaatacct tcacctctaa cctcagatgc aggataaaaa gattttttac
    38461 aatctctaga tcttaaactt ataaccttag tatcattaca gctatcatct atatcttctt
    38521 caccaaatat attattatca ggtggattga ctctactaaa cccagttaat gcccttactt
    38581 ctctaagtct ttttactaac actattttac tgaagtttgg aatatcataa tcagatagat
    38641 tttgttcttc tattgtaaag tcattagttt ttttagattt agcatctata tttccaatta
    38701 aagcctcata ttcttcttct ctatattgat ttctagttgt tgttgatggt gaagaatctt
    38761 caaaaggcaa taaatctttc aaaactatgg atactttatc agtatcaaaa cctgtttctt
    38821 tagcaatatc actggcaaag tcctcaaaat cctcatccat aaagcgttct aacttattct
    38881 ttttaatagc acgatctaag aatttcttaa atgtatcata acctttacta gatagcactt
    38941 tagaattaag agtatcagag tatggtggta taataattga actttctatc ttaggataat
    39001 atacattaga ggcacctctt tgagaagcaa atgaatattt agtgcattta tttacttttt
    39061 tattatacca aggcgaatta ccagagcatt taaacatttc cttatattca ctaggtacac
    39121 cataatcatt agatttagaa gattttaaac gcataaatgc gcccttcata ttagctttag
    39181 ctccacagct acattcaagt tctatacctt ctaatcctag gttacttttt ccagtcttca
    39241 ttaatatttg aggattttca caaatttctt ttcttccaga tttatttcta aaatgaaccc
    39301 attttaccca tggaaaatca tcaatatgac catgttcaca aatagtaatt ataccagtag
    39361 gtactaattg tttagtagac ttttttgtgc tacaagtaag gcaaataggt attttcatag
    39421 gtttatcttt atgagcattt ttataaagtt tctcccaatc ttctataggc ataaattttc
    39481 tacattttgg acaaaagtac catctaggaa acctaacaaa aggaacagaa gatctatcat
    39541 ctatagttgg aggtgttctt agttcattaa ccctcaatgt agcctgaagc ctatcatctt
    39601 gtattttaat tgtattagtc caataatttg gatgagcagt cattaatgtt tgatcaataa
    39661 aatctagcat agctcctggt ccaaaaacac ttgtagcttg atttattctt aaattatgag
    39721 ttttatcatc taattttata gacatattaa ttttcctcca attctataat ttcaacagta
    39781 cattgtttat caacatttct catagaattt aatgtttgtt tttcatttgt aataacatcc
    39841 ttatcataag gaattaaaag attattatat attttattat caaatttact agggcgctta
    39901 taataatgca ataaattatc tttatcagat atttgagctt tatcatgcca taaatccatt
    39961 ataatatcta attcagatga aatctcagat ttaaattcat ttactatatt atcatcagca
    40021 ttttgattat tttctctaaa tatatcgata gatctatcta ttatgaagtt ttttaaatct
    40081 tctacaccat ccatattttt tgaaaatcga cttgcaagat cattagcttg aagtcctaaa
    40141 atatgtctaa tcatacttat taatactgca tgcatgcctc tttctctagc tggttcagag
    40201 aaaggtgtaa tactagtagg ttcaacaaat ttatagaatg attgatgata actaaagaac
    40261 tgttcataat gagatctatc tcttgttttt gtaggattat ataatgtaaa tataagtcct
    40321 tcattacttc taccaactct actgctagct tgtatgtatt cagatgttaa cttaggctga
    40381 ccaactacta ccattaaatt taatctatca acatcaacac caactgaaat catattacta
    40441 gctaatagag tatcgacagt taaattatta gaagtaagag tattagatag ttcatctaaa
    40501 gttgtattta tcttagtaga agtaagtcta ctagtaagct ctctttgttc atttaggttc
    40561 cttaatgatt gataagggtg ggctgagact cttttacata atctttccat gttgtctttt
    40621 atatcgtcat ttaaaagtgt gctacactta cctaattctc tgatactatt aaaataagat
    40681 actagtgtcc aatatttatc caataaattc aactctacat tctccatcat tttaagtctt
    40741 tggagtaatg ctgacataag tctaacctct acagtaactt gagtttttcc agatggaata
    40801 acacctacat atagtcggcc acgtttttta cttaaaggca tctctttaac aaagaaagag
    40861 ttactagatg ttaatcctgg aggtggaaac tgagctacat tacgattata tagattttta
    40921 acttgatttt gtgcttttct tatagtagca gtagaagcta taatcttagg ttttataccc
    40981 ttatagctac acatagcatc aagtgcagtt tcatataaac ctaccatagt acctaaaggt
    41041 ccagaaataa gatgaagctc atcttgaatt attaactcag gagataagtt gctattatca
    41101 tcatctaaag caaaaagact agctacttct gtagtccaag ttatcattgc aaatttatca
    41161 actgtaccaa ataaaagtgt tggagggtta ttataaatct cctcatctac aacttgtata
    41221 ggtaacatat cttcaaatga acaatcttct tcaggacagc ataagtagaa tttcttaggt
    41281 ctagatttaa ttctatagcc ccaatcacca acagcttttt tagaagtttt atcccattct
    41341 ttaacaagtt ttgttccaca ccaaggacat tttagtaatt ggaatttatt atattttgat
    41401 tttaaattat ctaactcata ttcactattt atactagatc taaacttaat gttattacct
    41461 gttaagttat taagcatttc ttctgcctca tcattaaagt ttggagtttg atcactccca
    41521 atccacaaac caatagaaat ctcttttttc ccaagttcag acttattttc ttttctaata
    41581 atttcacagg cacaaattaa tatacttgct cttatgaatt gttgtgcagc caatagcctt
    41641 agtgtatatc tcattatgat agctgtaccg ttaccatttt ctttgtttct tattcttctt
    41701 aagaagatag taaaagcaga tagacctaag taggcctccg ttttacctcc accagtaggg
    41761 atccaaagaa ggtcaactaa atctctatgt ttagagtcag gattttctat cgaagataaa
    41821 catgtaagta tataagcaag ctggaatggt ctccaagcag aattatcatt tgagtaatct
    41881 atatagtcaa ggttattaga tccagggagt ctatccgtaa tatgtataga atgacatctt
    41941 tgcataagta tagctctatt cattagagaa aatgctctgt atacttcatc attagactta
    42001 attaaattta taccttctag cattctagac ttagtatctc tgcagttttt tatatgctca
    42061 tatgctacat ctttaaaaac atcactaaga tcttttgaat cttcttctag atcatctatc
    42121 caaatatcat aagcatcaac aaacttataa agaaaatata ttttcttatc tttactaaga
    42181 tcagagatat ctgataaatt tttcatagac agtaattctc tagaaacatc acttaattca
    42241 tctacattaa agtccaattt aggtacttca aaatgaggaa taaactcagt acaaagtttt
    42301 attaaagcat cattttgaat atcttgatct atagctacac catgaccagt agcaaaagtt
    42361 tttttatttc ggtaaagtaa gtctaaagat atttcctcag aatctaactt tttaaaagta
    42421 tttactgatc cagctgtaaa aatatctata aactctaaat cattgttatc ttcagctaat
    42481 accattagtt caggctggaa aatagtatta ttatatttct taggcccaga ttgactatta
    42541 accagcatac aagtaatact aacaaagtca tttgaataaa ttcttttaga taaaactata
    42601 tctaaatctt tagatatagg ttttttaata tagtttttat ccatatctat tgatactatt
    42661 aagttttcat gtggaacacg aacataacca ccagtcttat tctcatcatc agggcattgg
    42721 ttagctaact tgtataaaac aaatttagct tcagcattat caagtaaatc atgctttttt
    42781 agtaaattat aaaccttctc agatgttagt ttttgcttaa gatataggaa tgatccccta
    42841 agttctacat attcattaat tgtattgcta gaatagaagt cgtcaccagt atatttaaca
    42901 tgacagtctg tatataaagc atttctataa gtagcataat ttaccctgaa atttattact
    42961 tctgcatctt tttttaggaa aaaagtcata cccatagaag aaggtaaagt ttcattagac
    43021 atacttatag ctctatctag ttcattttgt gtatcatctg atgtaaatac attatcttca
    43081 ccatcatatt cagatgtatt acttacatca atattgttat taagtggata taaaatacct
    43141 gttgaataac gctctattgg actatctgtt attatttcat attttatatt ttcacaaaga
    43201 tcttccgaac caggtccaag aagttctttt cttacaagat ctagggtttt atctcttagt
    43261 tcactacaat tcatatttac ctcctattta tttaataaac actatataag tctaaaactt
    43321 tgttaacaag gtggggtgac agatacttat cacaactgtg tatttctcgt atttgtacag
    43381 gtgtaacata atcatttgta ttcccaagca tacttaaaac aactgcagac acttcatctt
    43441 taattatatc tgatttactg ctaaagaaat tatcagatac aaatgtatct atagattttt
    43501 ttattttagt gtgcaaagag cgtatacttt tagtagcatc atatacctcg gtatgatcta
    43561 atttagaatc tataacttta aatatctttt cgaaagtttt taaatatata ggacctatta
    43621 atcttttatt tgttacccag tttttgattg ttataggatt aatcttttca cctaaaacag
    43681 ctaaactgtt tgatacatca ttataattat atttactata agatatatag tttttaagtt
    43741 ctgatttcca tgaattagtt aatttataat catcaagata atgagatggc aataaattaa
    43801 gttctaatag cttttgtata acattaataa ctaattcacc ctcttcattt aagtaatcat
    43861 caacaaataa aaaccagtca ttaactttag cctctgaaag tttctttttc ctaacacttt
    43921 ttttatccca atctattgaa taggctattg ccttttttgt acagaatata tactcattat
    43981 tatcagaaat catgaatgat gtaacatgtt cttttttaga gttgtaaatc ccttgattta
    44041 tagatagaga taatataatt tcatttaaat ttatatcaaa tttataatta gatatatatt
    44101 catccataga atcatcatca gaaataggac tatcggtaga ataagcttct aatttattgg
    44161 tttcataagt tggtttaaaa ggttttatat caagtaagtt atatatttta ttattttttt
    44221 caattttatt tcttgcagaa tttatttgat tcatatagta attatatttg gataattcac
    44281 tattatataa atacagtgta atatttataa tcaaatcact atttaaaata tctaaatatt
    44341 tcaaatcata gaatccaaac ataataagat tttttattgt ttttgaatct ttaaattttt
    44401 cagcagaaat aacttgtaaa tttatatttc tagattttaa taaattttta agtataatag
    44461 cttcatattg tttttgtagc aatataacag gtgtatttgg tgtaaatgtt ttgtatttat
    44521 atgaagatac taatttattt agtgtattga atttggtatt attatcagat aattcattta
//
LOCUS       DAEPKC010000020        44128 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.020, whole genome shotgun sequence.
ACCESSION   DAEPKC010000020 DAEPKC010000000
VERSION     DAEPKC010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 44128)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44128)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44128
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.020"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(<1..766)
                     /locus_tag="KR294_001223"
     CDS             complement(<1..766)
                     /locus_tag="KR294_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HBH0239307.1"
                     /translation="MHKRLLTLFKLLNESDDKITCKTLSNHLKVSERTIRNDITSING
                     TLEKNGAIIKIKKGEGYYIDILNLALYQQYLALISDDIMDSSEIPDSPIERNQYILKY
                     ILYNNTYIKLEDLANSLYVSKFTILNDIKRIKPILSKYNLILVSKPYYGVKVEGKEID
                     IRRCISNNMINRNFENYIIGITDREIELFNNVDLIELQRVVLSEINKFNINFLDFNLK
                     NFIIHLAITVSRILDGYCLDNVLDVVLTDFQSNTTVE"
     gene            1000..1452
                     /locus_tag="KR294_001224"
     CDS             1000..1452
                     /locus_tag="KR294_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH0239308.1"
                     /translation="MVLQEKYIFIDKDLKSKEEVLNFIADSAYILGITTNKEALLKDL
                     LKRENEFPTGIKDGFAIPHTKSVNVKEASILYIKTTNELEWKTLDDSKVRYVFSLLAP
                     HKNEGNIHLKTLSKLATCLMEDDFTNEVKNASDASHLVKYITNKMKEE"
     gene            1455..1763
                     /locus_tag="KR294_001225"
     CDS             1455..1763
                     /locus_tag="KR294_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HBH0239309.1"
                     /translation="MKIVAITSCIAGLAHTPMAAKALEQAASKMGHEIKVEQQGAMGR
                     VNTITKEEAQDADFILIASDQTISGMERFDGKKVIKVKIGIALKKPEAVLTKCIEAIS
                     "
     gene            1877..2983
                     /locus_tag="KR294_001226"
     CDS             1877..2983
                     /locus_tag="KR294_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HBH0239310.1"
                     /translation="MSKKNKSLLSELKGHLMTGISYMLPLVIGSSLVVAIPKLTALAM
                     GITSLDAYKNVSGFYHILYLMEQVGWTGIGLLNTVLAGFIAFSIGEKPAMGAGFIGGL
                     IASNTNAGFLGAVIAGFFAGYVCKFLKKKIKISGSASGMMPLIIMPLITVGLTGFLMS
                     VVLAGPLGNINTSLNAWVAEMCQNGTNSVVLALILGAMIGFDLGGPVNKAAWMAGNAL
                     LLEGIYLPAILVNCAIVIPPLGYGLATFIRKSKFSNALAETGKGNIVMGIIGITEGAI
                     PFTLTNPLKLVPVNMIGCALGVGLSALLGVHAIMPPVGGLYGFISIGSGWAYLVGAIF
                     GALVIAILSTTLVDFNEDETTENTEFDEIELDIM"
     gene            3058..5736
                     /gene="mngB"
                     /locus_tag="KR294_001227"
     CDS             3058..5736
                     /gene="mngB"
                     /locus_tag="KR294_001227"
                     /EC_number="3.2.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosylglycerate hydrolase"
                     /protein_id="HBH0239311.1"
                     /translation="MKKTKVHVVPHSHWDREWYFTTSRSKIYLMKDFQDILDILEEKE
                     DFKYFTMDAQASLLDDYLKWRPQDEYRIRDLVQRRRLVIGPWYTQTDQLVISGESIIR
                     NLYYGIDRCNEFGEPMRVGYVPDSFGQSAQMPQIYRGFGIDSSLFWRGVSDDMVDTTE
                     FIWKGSDGSKVLAVQIPFGYYYGGNIPEDDSDLKEYLKDIIGKLKVKASTNNVYFPNG
                     FDQAPIRKNLPDILKKANEIDNENEYEISDIENYIDSVRNERNEFTELKGEFLNAKHM
                     RIHKSIFSSRSDLKIMNNKLENYITNVLEPLLTLSYSLGNEYPHLVIKDIWKLMFENA
                     AHDSIGSCNSDTTNEDVYTRYKQARDLSINLLDLHMRLISTQIKNNNEEITLTVFNGF
                     PEVRNEVVEFDTYIPGQDFVIKNKNGKILNYIIKEKEDITNYILTQTIRLNPSKKIYI
                     PKTVYRAKIALSVKDIPPMGYTQLVFELDTKNKCEIETSNCKEIENKYYKITANKNGS
                     LEILDKESNKTYKNQAVIEDNGDDGDSYNYSPPRKDIYVSSLDSVSSVEVLKSNIQEE
                     MILKYSLTIPTSLEERAIGKVSVKMPVTMKITLEPKEQIIKFNVNIKNNQALSHRVRV
                     LFNTEIASKFSIADQQFGIIQRPTVLEKDLALWKRDNYSWQEKPITIEPMQSFVTLED
                     GQRGIALITGCVREYQIVGDNLDTIALTLFRSFGYMGRENLLYRPGRASGEKIIATPD
                     AQLLKELNFDFGLYIYNNKFDEANVANTAKRFLTPIQIYEYADFLNGRLIFAFNDEKQ
                     IYENEFSLMNVNNSNFTVSAIKKEEKGDGIVVRIFNGMKNEDAKGSLNINKNVNDAYS
                     AMLDEIYDNTSKLKVNTKTVEVNSLSHCKVQTIVIK"
     gene            complement(6053..8386)
                     /locus_tag="KR294_001228"
     CDS             complement(6053..8386)
                     /locus_tag="KR294_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBH0239312.1"
                     /translation="MDTKLKKFKDKYIVTIIVFILMLSASLGMISQYSTIQASAKGGA
                     ENPFEQESFVDSIYKGSYVLYHNMKEEQEGKMIQPSKLFINEETMNYIKNVSKEKDTY
                     DGSETYYTDDSINADFNENFENWEHFIKASGKNLKYYLVDKESNFEFFNDNKELGVLD
                     TTKNDASKENSNENQSKNTEMNDEERQKQITDIKENYRFYVVMNFDKDGKVNIVDSYG
                     VNQKIINQMLLSKAREDLMDTSLGGNSISYKLSPIKNITLVYAVPKVISKGDSVEYGY
                     GNTYFDDGIISYISNVENNSYYKISGMILKIILAIVVIVALAFPYRKSKELLGFDTLS
                     RIPLEILFIALAIIQGLVDLYPTVIISNTLSGNYVEYLINNDISAKMASILVSLMNLT
                     YWFVIFSIIFVFIILLKHILNVGIREYFTKHTVTGMFFVWLKKAGKAVINQIRTINLK
                     EKPNKTIVTILGINLLIIVIMCSMWFFGIILALIYSVVLFKILSDYSKKTIYEYNQLL
                     DVTKKISDGNLDVNMEKDLGFFNPIKDELGNIQTGFKKAVDEEVKSQKMKTELISNVS
                     HDLKTPLTSIITYIDLLKDESITDENRKLYIDTLDRKSQRLQHLIEDLFEVSKANSGD
                     VYLNIVNVDIVSLMKQTLLELDDKLADSSLIVKNNFSNEKIILPLDSQRTFRVFENLI
                     INISKYAMPNSRVYIDILETDNKVNIMLKNMSASEIDFSVDDIMERFVRGDKSRNTEG
                     SGLGLAIAKSFIELQGGKMNISVDGDLFKVTITFNKN"
     gene            complement(8361..9077)
                     /locus_tag="KR294_001229"
     CDS             complement(8361..9077)
                     /locus_tag="KR294_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0239313.1"
                     /translation="MNSYNILVVEDEKEIADAIEIYLLNQGYNVFKGYNGLEGLKVIE
                     NQEIHLAIVDIMMPKMDGITLTMKLRENYNFPVIMLSAKSEEVDKIMGLNIGADDYVT
                     KPFKPLELLARVNSQLRRYTKYLNMVGNKEQKVESDDSVFAIGGLELNENTKEVSIDG
                     KYIKTTPIEFKILSLLMRNAGRVFSADEIYERVWNENAVNTDTVMVHVRNIREKIEID
                     PKNPKYLKVVWGVGYKIEKI"
     gene            complement(9492..10148)
                     /locus_tag="KR294_001230"
     CDS             complement(9492..10148)
                     /locus_tag="KR294_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBH0239314.1"
                     /translation="MELQDTIFKRQSVRKFKNQDVSDEDILKMIKAAGAAPSGKNIQN
                     WHFVVIKRRDLMEKIADVITKKQQEILVEMDKVSVDKANRFRKFVKNFTLFYLKAPVL
                     VLVFTKVYNPSGYYELELIDAPKETIDKLFIRNPGMQSLGAAIENFTLSAIELGYGSC
                     WLTSQNYAADEIEAVLEAETGFEKGEYFLGAMLALGVPEDNLKSPSKKPVEEICTFIK
                     "
     gene            complement(10203..10832)
                     /locus_tag="KR294_001231"
     CDS             complement(10203..10832)
                     /locus_tag="KR294_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBH0239315.1"
                     /translation="MVDSIIFDLDGTLWDSTEEVCKVWQDVLSEHKEIELSVTKDLFR
                     SLMGLSFEEIANRLFPNLSEEERMNLLNECSLKECDYLSENGAKLFDDIEDTLKLLSK
                     KYKLFIVSNCQAGYIESFLKAHKLEQYFIDFECPGNTGLHKGENNKLIIERNKLINPI
                     YVGDTQGDANSAKFVGIPFIYAKYGFGNVDVYDYFIDSFKDLLEHDILK"
     gene            complement(10963..11604)
                     /locus_tag="KR294_001232"
     CDS             complement(10963..11604)
                     /locus_tag="KR294_001232"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HBH0239316.1"
                     /translation="MKICIVLNGEIEDYEVTRDIIIKECYDCIICADGGANHTYKMEI
                     MPDYILGDLDSVEEEKINFYKNKGVKFEKFPSKKDETDTELCLFLAKTLKANHIDFFG
                     ALGGRIDHTLANIKLLYYLKEDGIYSRILSDKEEMYIVENEEISLYGNPGDTISVIAI
                     NGDAKGVTLTGLEYPLDNYYMKYSVPIGISNVMLSNSCKIKVEQGCVLVVRNL"
     gene            complement(11613..12284)
                     /locus_tag="KR294_001233"
     CDS             complement(11613..12284)
                     /locus_tag="KR294_001233"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HBH0239317.1"
                     /translation="MIKLAPSILSADFAKLLEDVRKVESAGCEYLHIDVMDGHFVPNI
                     TLGPLVVKSLKKENINMVFDAHLMIENPDQYIEEFVKAGCDIITVHQEACVHLHRTIQ
                     NIKSHGIKAGVVLNPATPVDTIKHVLSDLDMVLLMSVNPGFGGQSFIPCVLDKIKELK
                     AIIDSQGLNIDIEVDGGISPKNVAEVVQAGANVIVAGSAIFGSDDIQETVNLFRKNAS
                     LEELV"
     gene            complement(12289..13173)
                     /gene="rsgA"
                     /locus_tag="KR294_001234"
     CDS             complement(12289..13173)
                     /gene="rsgA"
                     /locus_tag="KR294_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HBH0239318.1"
                     /translation="MLEGKIIKGISGFYYVDTYNGIYECKARGIFRKQKITPLVGDRV
                     KISIVDEDEKKGILEEIDSRDTELIRPPIANVDKALIVFAIKNPKPNLSLLDRFIVLA
                     EKENLETVIILTKADLDDNDTLETVKNIYELSGYKVIPVSNITKLNIDKVKEELKENV
                     VVFAGPSGVGKSSLLNEIDENFKLQTGVVSDKIKRGKHTTRHAELLKLEFGGMVADTP
                     GFSSLALEDIEEVELKDYFIEFDKFNDCKFGSKCIHENEPNCAIKEAVTNGEISKERY
                     DSYIQLLHEIRQNNSRRY"
     gene            complement(13271..14008)
                     /locus_tag="KR294_001235"
     CDS             complement(13271..14008)
                     /locus_tag="KR294_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBH0239319.1"
                     /translation="MKKKTVLITGGARGIGKAMSKAFAKEGYNVLVNFNKSENEAKEL
                     YTILNEKNFSVKLFKANISNREDVEDMVDYCIKEFGGLDVLVNNAGVSQDKLFTDITD
                     EDWDNMMNINLKGSFYCSQVALKYMISEKKGNIINISSIWGISGASCEVHYSITKAGI
                     IGMTKALAKEVGPSNIRVNSIAPGVINTDMLSGYNEEDIDALVEETPLMRLGTPEDIA
                     NCAIFLASDKSNFITGQVISPNGGFVI"
     gene            complement(14116..16131)
                     /gene="pknB"
                     /locus_tag="KR294_001236"
     CDS             complement(14116..16131)
                     /gene="pknB"
                     /locus_tag="KR294_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HBH0239320.1"
                     /translation="MGDTILGNRYEIIRKIGDGGMAFVYEAKDRLLNRTVALKVLRPE
                     FVDDDEFLTKFKREAEAVASLSHPNIVNVYDVGEDGKVHYIVMEFVDGKNLKEIIQDE
                     GILDEYTALDITKQIAMALSAAHKKGIIHRDIKPHNILISNEGRVVKVADFGIAKAVS
                     NSTMTNIGSIIGSVHYFSPEQAKGKFVTNNADLYSLGIVLYEMLIGKVPFRGDSPISI
                     ALQHINDDIDFTSEEKVRIPQSVRTTIKKLTEKSSADRYQTAEELIEDIEYIEKNIDL
                     DFIKEYDDFATKKIDEKEINKVVNPTLAKPAPEKVVKPVEVADLDDDEDYYDDFYEED
                     DDEDEEEEEIMRAKKNQRPKSTPSKRTKKKKKKQESPKSRRRLKVIAAVLILILCAQV
                     FLAYKFLFAGGFGNKSLTVPNLVNMTLEEAQSAVEKEGLYLSVKSEEYNSEVDENCII
                     SQTPEGGSTNVKKGDTINVVVSKGSSQASVPNVVGLTLSNAKQLIEENNLKVGTVKYE
                     YSSIYKEGTVLSQSPGAGSSRAQEGDEVNLYVSKGSEKSNTQTPTVPDKKPTTPENNT
                     PTEPGSNSGNSGGNSGGSNSGNSGGNSGNNGSNSGGSNSGNSGGNSGGSNSGDNGGSS
                     GGSNSGDNGGSSGGSNSGDNGDSSGGSNSGDNGGTSSGTGANIGKTE"
     gene            complement(16148..16900)
                     /locus_tag="KR294_001237"
     CDS             complement(16148..16900)
                     /locus_tag="KR294_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HBH0239321.1"
                     /translation="MVYSCASHIGKIRKNNEDYCEGEVIDTEHGPIGIFAIADGMGGH
                     KKGEVASKLAVENIIDFLKENLLQHDNVKIDYIDDILKQAYNNVNSIVHKKSMEDIEF
                     EGMGTTLVTAIVYNNVLYVANVGDSRCYLLTDEKFDKITIDHSVVEELMMAHVITEEE
                     ARRHPQRNRITRAIGTDDMVVVDIFKKEIKKSDIILLATDGLTGFIDDEDIRDLILDY
                     EYERTSNISEELISMANDVSGKDNVSVIVIKV"
     gene            complement(16920..17951)
                     /gene="rlmN"
                     /locus_tag="KR294_001238"
     CDS             complement(16920..17951)
                     /gene="rlmN"
                     /locus_tag="KR294_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HBH0239322.1"
                     /translation="MEKKKIVLKNFTEDELKEFMKTIDEKPFRGSQIFSWIYKGAKTF
                     DDMNNIPKSLRNKLEEVSCIGHIDIELKLESKVDNTKKYLFLLDDGNIIETVMMDYDS
                     RVTVCVSNQVGCRMGCNFCASTMDGLIRNLEPWEILDQVIKIQEDTGKRVSNLVLMGS
                     GEPLDNFENTKQFLKIINEKNGLNIGYRHITLSTCGIVPKMYELADLEIAINLALSLH
                     SPYDEERRKIMPVANAYSIEEILNACRYYIKKTNRRVTFEYSLIKGVNDSEKEAKALA
                     KLLKGMLCHVNLIPINKVEEREYEKPDKAFIYKFRDSLEKNNIPATVRMSMGSDISGA
                     CGQLRRKYK"
     gene            complement(17959..19284)
                     /gene="rsmB"
                     /locus_tag="KR294_001239"
     CDS             complement(17959..19284)
                     /gene="rsmB"
                     /locus_tag="KR294_001239"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HBH0239323.1"
                     /translation="MDAREVGFKVLCDIEKNDNYSNIAINKHFKNLEISDMDRGLATE
                     LIYGVIENKYYLDYIINKLSKIKVKKMSTYVKIFLRMGTYQILFLDSISDYAAVNETV
                     KLSKKYDKKSSGFINAILRNEIRAKETIMDITEEDSVKYLSIKYSYNSWIIKNWIDKF
                     GQEFAEDLLEANNEKPSIYIRTNTLKISREELIEKLSEMGIVCLKVPMVEEAIKVEKM
                     KNIEKNELFKAGLFTIQDISSMIVGKVINPKEGSFVLDVCSAPGGKSTHLATLMNNTG
                     QVVARDIFEHKLKLINSTVNRLGLKNVFVERFDASEIDENSISKFDYVLADVPCSGFG
                     IIRRKPEIKYKKEEELKDITSIQKKILENASKYVKVGGTLVYSTCTIQDVENINIVTS
                     FVEENHNFEFVPIDTVNVDLDNQDKGYLKIYPNIHGIDGFFIAKLKRIR"
     gene            complement(19346..20047)
                     /locus_tag="KR294_001240"
     CDS             complement(19346..20047)
                     /locus_tag="KR294_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HBH0239324.1"
                     /translation="MYPVYGGFWGFDPTMVVLIPAILLTIYAQFKVSSTTNKYLRVNT
                     RRGYTGEQTARRVLDSNGLYDVKIEMVRGHLSDHYDPRRKAVRLSEDVYYGTSITSVA
                     VAAHECGHAIQHAKGYAPLQIRSSLVPVVNFASSISWFLIFLGFIMAGPFLKIGILLF
                     SASVLFQIITLPVEFNASSRAIVQLGNLGIIDESESRQSRRVLSAAALTYVAAALVSI
                     LQLLRLLLIAQRRND"
     gene            complement(20116..20868)
                     /locus_tag="KR294_001241"
     CDS             complement(20116..20868)
                     /locus_tag="KR294_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF116 domain-containing protein"
                     /protein_id="HBH0239325.1"
                     /translation="MTDIKKYLTSVGILILILGILIGVVNFFIISLTQIFSLMINIII
                     ISLILIILCSTVVTYRVIKGKYVNSNIMKINFNIVSGLFPIISFIASSFGMSKSDIRR
                     IYIKLNNEYIYSNKYNFNPEDIIILIPHCIQENSCKLKVTNDIDNCKECGRCNIGELI
                     KLKEKTNVKIFVATGGTLARKIIMDTKPKAVVAVACERDLTSGIQDIKKIPVLGVFNK
                     RPNGPCVNTNVDMMDIEKAIGFLTGKNILVCN"
     gene            complement(20878..21807)
                     /locus_tag="KR294_001242"
     CDS             complement(20878..21807)
                     /locus_tag="KR294_001242"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HBH0239326.1"
                     /translation="MKIVFMGTPDIAVPCLQKIIDEKYEILGVVTQPDKPKGRGKKLG
                     MSPVKELAIENNIPVYQPVKARDKEFIDKIKSLNPDVIVVVAFGQILPKEILEIPKLG
                     CINVHVSLLPKYRGAAPINWVIINGEEKTGVTTMYMDEGLDTGDMILKTEVNLDENIT
                     AGELHDKMMNIGAETLKETLRLIEEGNAPREVQNHEEFSYAPIMNKSLGNIDFSKSAR
                     EIHNLVRGVNPWPSAYTTYNDVIMKVWKTKVLDEKSTKDVGTIIDVSKDGIKVSTIDN
                     VLLIEEIQMPNKKRMLVGEYIKGNTIETGLVLG"
     gene            complement(21822..22262)
                     /gene="def"
                     /locus_tag="KR294_001243"
     CDS             complement(21822..22262)
                     /gene="def"
                     /locus_tag="KR294_001243"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HBH0239327.1"
                     /translation="MALRQIVQIGEPVLRKKSKKVEKIDEKIIQLLDDMAETMYDADG
                     VGLAAPQVGILKRVVVIDIGEELIELINPEIIETSGEQIDEEGCLSVVGEAGNVRRPN
                     YVKVRALNRNGETIELEGEELLARAFCHEIDHLDGILFVDKIEK"
     gene            complement(22280..24805)
                     /gene="priA"
                     /locus_tag="KR294_001244"
     CDS             complement(22280..24805)
                     /gene="priA"
                     /locus_tag="KR294_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HBH0239328.1"
                     /translation="MNNILNLSRGFIMKKYAKVIVRSNTIYTDNLFTYQIPVFLSDVI
                     KIGHRILVPFGKGNKPTEAFVFQFTDSLDEKIKIKEIIDILDENPIFRKEDLELVYWM
                     KNRYLCTYIECINLIYPKGYKLNNYKVVLLGESLSGLNDIELKEKISTLSDKNREIVE
                     KVIDSKGKIKVDKLKYIPNLNSSLYTMNKNGIIKLCWEYKNHKNEKKVCYISLSLESD
                     KIDDYIEQNKINVGSKQKEILSFLKNNENVEINDLLDLLNASKQSINSLSKKKLITLE
                     FKDYYREPKSIYKSVLKSIKLNNEQQEAVDEIKSNMFVDDKKPYLIHGVTGSGKTEVY
                     MEIIEFALNQGLDSIFLVPEIALTPQTIDRLKSRFGDLVGVFHSKLSEGEKHDVYKAV
                     KAGKVRVLIGARSALFAPFNSLGLIIIDECHESSYKSEKNPKFNAIEVARFMALKNNI
                     TLILGSATPSIEEYYRAKSGEYKLINIKSRANDKPLPNIEVVDMKDELDKGNRSIFSL
                     KLQKEIRYAIEENNQVILFLNRRGYANFVSCRKCGYVFQCENCDISLTYHKKSNTGRC
                     HYCGYEKEIPKECPECKSTYVKPFGVGTQKIEEELKYIFPDIKTLRMDKDTTSKKGAL
                     DEILNKFKDKEADVLIGTQMLSKGLDFENVTLVGILSADMILNFPDFKSFETTFQLIT
                     QVSGRAGRADKEGKVVLQTYDTEHYAIKHAIEYDYEGFYEDEIKIRKAFGYSPFNNML
                     SVVVSGEDERLVIKNIKNMHASLIYLLEKRGINDLGFILGPNPCSISKINQNYRWQIL
                     FKDENIEINLLKGIIKYICITKRDLIFDKNINVSIDINPNSVL"
     gene            complement(25044..26243)
                     /gene="coaBC"
                     /locus_tag="KR294_001245"
     CDS             complement(25044..26243)
                     /gene="coaBC"
                     /locus_tag="KR294_001245"
                     /EC_number="4.1.1.36"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphopantothenoylcysteine
                     decarboxylase/phosphopantothenate--cysteine ligase CoaBC"
                     /protein_id="HBH0239329.1"
                     /translation="MLKDKTVVIGISGGIAAYKACDVVSKLKKLNANIHVIMTKSATE
                     FVKPLTFQSLSQNYVVEDMFEEPKTWEVEHISLAKKADLFLIVPASANVIGKIANGIA
                     DDMLTTTVMATKAQVLIAPAMNTNMYENPIVQKNIQTLKSFGYKFIEPESGRLACGDI
                     GTGKLANPDIIVEEVLTNLTKEQDLKGQSMIVTAGPTVESIDPVRYLTNRSSGKMGYS
                     IAREAIARGADVTLISGPTNLSIPQNLKKFVQIESAQDLYEAVVSNLSENKIVIQSAA
                     VADYKPKTYSDKKIKKKNDDLSIELSRNYDIAYEIGKIKEDKILIGFAAETNDLIEHA
                     KGKIKKKNLDFIVANDLTKEGAGFRADTNIVKIIDVEGNITEYPKMKKEEVANVILDK
                     VKALLEK"
     gene            complement(26248..26514)
                     /locus_tag="KR294_001246"
     CDS             complement(26248..26514)
                     /locus_tag="KR294_001246"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HBH0239330.1"
                     /translation="MLKPSINEVLEKIDNRYYLVGTVSKRARKLIDGEEPYVSNKTKE
                     KPVCVATKEVASGKITYRLLTEEEIEIEEARHHAEQHQQISEEE"
     gene            complement(26517..27134)
                     /gene="gmk"
                     /locus_tag="KR294_001247"
     CDS             complement(26517..27134)
                     /gene="gmk"
                     /locus_tag="KR294_001247"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HBH0239331.1"
                     /translation="MFVKKGLLLVVSGPSGAGKGTICKELLKENDTIKLSVSATTRKP
                     RTGEVDGVNYFFISKEKFEEMIEKGEFLEYAQIYDNFYGTPKAAIMECLEKGQDVLLE
                     IEMQGAKQIKEVCPEGVFIFVLPPSLEELKNRIVGRGTETEAEIEKRFSCAYEEIKMI
                     KDYDYFIFNEDVKTSAKEIEGIISSEKNKVSRYKNIIIEKFKEEL"
     gene            complement(27164..28045)
                     /locus_tag="KR294_001248"
     CDS             complement(27164..28045)
                     /locus_tag="KR294_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HBH0239332.1"
                     /translation="MAISMTGFGRGEYKDDNYYFLVECKTINHKYSDINIRLPRKISF
                     LEDKVRNLVKNYVKRGRVDLYIKFDLLGKEDVNLNFDEGLASQYIDILKEIKNKFDII
                     DDISVMNVAKFPDIVKIEEKEEDEDLLWSMLNQAVEDALIKLREMRSEEGKKLAEDIA
                     MRCDLLKNHIEEIEKYSSSVVEDYREKLNLRISELLDDPSIIDENRLAQEVAIYADKS
                     SITEEIVRFKSHIGQLKNTIFKDDSIGRKIDFLIQEMNRETNTIGSKSSDINITNLVV
                     EVKSELEKIREQIQNIE"
     gene            complement(28049..28879)
                     /locus_tag="KR294_001249"
     CDS             complement(28049..28879)
                     /locus_tag="KR294_001249"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HBH0239333.1"
                     /translation="MKFWKLHGIGNDFIAIDGRFDQINPSDYTALAKKVCHRRFSVGA
                     DGLLVVKDSKVADVEMVYYNSDGSRAAMCGNGLRCFCKFVYDNCIVKKESFTVDTLDG
                     IKDIKVNLTNREINSIRVNMGKGSFIAKDVPVLTNKERFVQESIKVLDRELKVTSMLM
                     GVPHTVVIVDELDVDDVCKYGKEIENNKIFPEKTNVNFVKVEDKYNIHVYTWERGCGY
                     TLGCGTGMTASAIVCNLLNMVESSVNVTSQGGTVKIDVGDFSYMTGPAVKICEGILEV
                     "
     gene            complement(29166..30200)
                     /gene="ltaE"
                     /locus_tag="KR294_001250"
     CDS             complement(29166..30200)
                     /gene="ltaE"
                     /locus_tag="KR294_001250"
                     /EC_number="4.1.2.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low-specificity L-threonine aldolase"
                     /protein_id="HBH0239334.1"
                     /translation="MRFIDLRSDTVTMPTDEMREAMAKAPVGDSIFRDDPTVNKLEEL
                     AAAKVGKEDAIFLPSGTFGNQLALFTHCLRGQEIIIGKGYHIVTHEVGAPAVIAGVQL
                     RTIDEDESGALNPELVEKAIRRDDIHEPQTGLICVENAYSGGTVVSLDNLREIKKIAE
                     KHNLPVHLDGARLFNAALTLGVEAKEIAKCCDSVMFCVSKGLAAPMGSILAGNKEFIA
                     KARRKQKVMGGGMRQVGIVAAAGIIAIEKMTLRLNEDHENAKYLACELNKIDGIEVNN
                     VNPDISMVFFKMSEDIIKEDVLIKEFFERNIKINKMENGEYRFVTHVDITKEDLDYVL
                     KTLKELIGVC"
     gene            30496..32271
                     /locus_tag="KR294_001251"
     CDS             30496..32271
                     /locus_tag="KR294_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NFACT family protein"
                     /protein_id="HBH0239335.1"
                     /translation="MALDGLVIHSIVDELSSKLTGGKIDKIHQPEDDEVIFNIRNNKE
                     NFRLVLSASASNPRVYLTSNYQKENPLKAPMFCMLLRKYIQGGNIVEISQIGFERIIK
                     ISVESLDELKEKTVKNIMIEIMGRHSNIIITHGEENKIIDSIKRVPFSISRVRQVLPG
                     HDYSLPPEQNKLNPLDDISKDLFIKNLEELEGPIFKSIYSKFLGISPIIAKEICYRAG
                     VNQNAIIKDISDEQFDALHKVFCNLFNDINSNKYSPCIIIDKKVDKVVDFSCINLTLF
                     SDLSYINKDSMSRILEDFYRTKDIKDRINQRSSDLKKSISVKLDRLYNKLKKQEEELS
                     ESENADIYKIKGELITSYIYMVEKGMESIEVANFYDENCNDVTIELNKNLTPSENAQK
                     YFKKYNKMKHAKVEISHQISLNKEEIDYLENIILSIENCENLAELQDIKEELAKVGYI
                     KTQKKNSKKDTIPSTKPHEFVSSDGFKILVGKNNKQNDYLTLRLADNDDLWMHTKNIP
                     GSHVIIKCAGKEVPDNTVFEGAMLAAFFSKSKLSSQVPVDYTKRKNVKKPSGSKPGMV
                     IYETNSTIYVTPEEETVAKLKVKSE"
     gene            complement(32486..34138)
                     /locus_tag="KR294_001252"
     CDS             complement(32486..34138)
                     /locus_tag="KR294_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBH0239336.1"
                     /translation="MLLVKVENLKKYYADKLILDIDKLEILENDKIGLVGSNGQGKTT
                     LLKAILGEIEIDEGYTYLTESYSYISQSENNIETCSHSKEKSLLNAPDKFEEHLSGGE
                     KVKLKIADALSNKKNIIIADEPTSNLDKKSIGVLEDMFKRHEGALLLISHDRRFLDEL
                     CTTILELEDGKLKAYKGNYTDYLMQKDEEVKRADFEYQEYVKEKKRLEKALLYKKALS
                     DGIRKTPKRMGNSEARLHKMGGQTNKKKLDSNVKAIKSRIDKLEVKNKPKVSKEMNIK
                     MQDGMEIISKNLVEVKDMTLKLENKLLLDNVSFKIKRGKKIALLGDNGCGKSTLIKEI
                     LADKNDNIKINNKVKVGYFDQNQSLLDEEKSVLYNTKVNSSFDESFIRINLSLFGFKG
                     DDVYKKVKVLSGGEKVKIALCKIILEDNNFLVFDEPTNYLDIKSMEALEKALINTDKT
                     MLIVSHDRVFVSHICNYIIEIKDAKIREFDCNYDEYTISRNKKTPSRENQIKKENLLV
                     LENRLTTVISMLSIEKDNLKKELYESEYNELLKQINKLKNSF"
     gene            complement(34437..35648)
                     /locus_tag="KR294_001253"
     CDS             complement(34437..35648)
                     /locus_tag="KR294_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HBH0239337.1"
                     /translation="MKKTIMSLQHLLAMFGATVLVPILTGFNPSVAIFCAGVGTLIFH
                     FCTEGKVPAFLGSSFAFIPVILAAKEAYGGDLAYAQGGIIVAGLIYIIMSIIVKVVGV
                     NKIKLYFPAQVTGAMIVVIGLNLLPTAFSMASANFVIAFITLAIAILTNKFGRGFIKQ
                     LGILIAVFSGYIICLILRLVDITTITEASLFAIPNFTVPKFSLGAIVIISPVVLAVFM
                     EHIGDMTTNGAVVGKNFIENPGLNRTLLGDGFATIVAGCLGGPANTTYGENTAVLAIT
                     KNYDPSILRRTAIFAILLACVGKFGGFLQSIPGSVMGGISIMLFSMITYVGLKTIRDS
                     SCVESKINILIIAVILLIGLGTTYLSNKGISVGIPITSTVKITGLSLAAIVGIVLNRI
                     LNNQDFKVEEE"
     gene            complement(35932..36465)
                     /gene="pyrR"
                     /locus_tag="KR294_001254"
     CDS             complement(35932..36465)
                     /gene="pyrR"
                     /locus_tag="KR294_001254"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001156491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HBH0239338.1"
                     /translation="MVEKAQLMDEKAIARAITRISHEIIERNKGVENLVLVGIKTRGV
                     PIANRISKKIEQIEGTKVDTGDIDITLYRDDLEKIHVEPVVKGTYLDFNVNDKTVVLV
                     DDVLYTGRTVRASLDAIIDIGRPKSIQLAVLVDRGHRELPIRADYVGKNVPTSRHEII
                     SVSLLEIDGEDSVTIKE"
     gene            complement(36825..37772)
                     /locus_tag="KR294_001255"
     CDS             complement(36825..37772)
                     /locus_tag="KR294_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBH0239339.1"
                     /translation="MFYFLKVKVGDIMDEVKEFLVLEEEEEVRLDIYLAEQLGDMSRS
                     YIQKIIKDGKVKVNNKVEKARYLVKEEDNIVIEIPEPKVLEVLPQDIPIDIVYEDDDV
                     LIINKPQDMVVHPAPGNYENTLVNGILYHCKDKLSSINGVIRPGIVHRIDKDTSGLLM
                     IAKNNYAHNFLAEQLKEHTITREYEFICYGVVKEDKITVDKPIGRNPKDRLKMAVVKD
                     GKNAITHFEVVERFDKFTHMRARLETGRTHQIRVHALSINHPLLGDYVYGPKETKFKL
                     KGQTLHAKKLGFIHPTTKEYIEFNSELPEYFKEVIKKIK"
     gene            complement(37741..38187)
                     /gene="lspA"
                     /locus_tag="KR294_001256"
     CDS             complement(37741..38187)
                     /gene="lspA"
                     /locus_tag="KR294_001256"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HBH0239340.1"
                     /translation="MLYILIIILLIGLDQLSKIWVLNNLVDVSTIPIINNVFHLTYVE
                     NRGAAFGLLQNNQWIFIIVALLATVFGLYYLNTRKVHIFGRLGIILIISGALGNLIDR
                     VRLGFVVDYFDFRIIWEYVFNIADVFVVVGTVFLCIYVLFFESKSR"
     gene            complement(38497..39276)
                     /locus_tag="KR294_001257"
     CDS             complement(38497..39276)
                     /locus_tag="KR294_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBH0239341.1"
                     /translation="MKKIIWGICICLLSIVGVYTYNHNTHNQDSSKEAYSLNDNIKDD
                     YEDVIIKKGNEDEKILALTFDDGPDEDFTPQVLDILKKNDVKATFFVVGEKVEYNKEL
                     LKRQYDEGHEIGNHTFTHINVAKNSYSSVEKEITDTQNIIKSVIGVEPKIFRPPYRAM
                     SKSVCDIIVSKGMNIILWSNLDPRDWSNPGVDAIINTILTKVQNGNIILLHDYNTKRN
                     DKSQTIQALEVVIPKLKERGYKFVTVSELIQHLDKNKQVQK"
     gene            complement(39331..39813)
                     /locus_tag="KR294_001258"
     CDS             complement(39331..39813)
                     /locus_tag="KR294_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraR/DksA C4-type zinc finger protein"
                     /protein_id="HBH0239342.1"
                     /translation="MDTKKYKDKLLKERENLTNLVEDMKDNTLFGDTTKHTSEKYSSG
                     ELSSYDNHIGDMGTDLYMQNMQNSLINHEEGRLYQIDLALSKIENGTYGICDLCHNQI
                     DLERLDILPDTSLCNDCAKKENNLLGDAMQNPDVEDSNFYSEDLTNLTDLNKNGILRD
                     "
     gene            complement(40079..41500)
                     /locus_tag="KR294_001259"
     CDS             complement(40079..41500)
                     /locus_tag="KR294_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon starvation protein A"
                     /protein_id="HBH0239343.1"
                     /translation="MVSFLGSIVVLIVGYFVYGTFVEKVFGTNDKNQTPAIACRDGVD
                     YVPMKWKRIFLIQFLNIAGLGPIFGAIQGALFGPSAFLWIVFGTIFAGGVHDFASGYL
                     SMKNKGTSASELVGLYLGNGAKIAMRIFSVILLVLVGVVFVTGPAGLLKTLTGVNAQI
                     WVGVIILYYIMATVLPIDKLIGKIYPLFGAALLIMAVGVAGGLIIKGYNIPNINLQNM
                     NPNGTPLFPYLFITIACGAISGFHATQSPLMARCVEKESEARPVFYGSMVAEGIIALV
                     WAAAAMSYFHGIPQLNVIFNDGGAATVVNTVSVGLMGPIGGALAILGVVACPITSGDT
                     AFRSARLTIADAMNYNQDAVKNRFLIALPLFAVGVALTFIDFNIIWRYFSWANQTLAM
                     IMLWTGSAYLVKANKNHYITTLPALFMTVVTFSYIMQAKEGFRLPVNISNGIGVIVAI
                     ILGLLFFKKAKHIKEQNNHKLAS"
     gene            complement(41646..42416)
                     /locus_tag="KR294_001260"
     CDS             complement(41646..42416)
                     /locus_tag="KR294_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001295458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0239344.1"
                     /translation="MRAIIVEDEFPARKELRYFIENKSGIEVVSEFTNGIEVLDFIQE
                     NKIDVIFLDINIPHLDGMLLAKTLNQFKSRPKIVFITAYESYAVDAFSLDVFDYILKP
                     YSEERIISMLNKLEKSEMSDIELFNVNSNLYKYKKEAVNQEIEEITHKISLWKGDKLV
                     VIDIDDIYYCEANERQTFIYTEKEKFILKEGISEVENLINDKTFFRTHRSYIVNLTKV
                     KEIIPWFNNTYILKLKNSDYEVTVSRSKVKEFRLLMHI"
     gene            complement(42421..43623)
                     /locus_tag="KR294_001261"
     CDS             complement(42421..43623)
                     /locus_tag="KR294_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBH0239345.1"
                     /translation="MKTSILIALIEKTSLIVVLFLLITKLKIFKQIFQKEEYSFNDLV
                     CIALVFTFLAIFGTYSGINYMGSIVNTRIISIVSGGILFGPMVGITAGVFSGIHRYFM
                     DIGGITSVPCLLSSILAGVLSGFLYKRIPKQHRVMYGILVGMISESFTILLIYLISYP
                     HSLAIQIIGGIYLPLIVGQIGIGFVISIVEGIEKDKKDIEARNKAEIKALQRQINPHF
                     LFNSLNTIASFIRFSPDKARELIINLSTYLRYNLEYSDNLIDINKEIEQVKSFVEIEK
                     ARFGELLTVSYDIEDVNIKIPSLIIQPLVENAIIHGILESGRAGVVKISIKKLPYSLE
                     NTVRISIEDNGIGISEEIINNVYQDNMPENKIGLYNVHLRLKLMYGRGLNIRRIDNGT
                     LIVFYVKE"
BASE COUNT        14565 a         7685 c         4721 g        17157 t
ORIGIN      
        1 tttcaacagt tgtattcgat tgaaaatctg ttaaaacaac atctaaaaca ttatctaagc
       61 agtaaccatc aagtattcta cttacagtaa tagctaaatg gataataaag ttttttagat
      121 taaaatctag gaaattgata ttaaatttat taatttcact taacactacc ctttgaagct
      181 ctattaaatc tacattatta aataattcta tttctctatc tgtaattcca attatatagt
      241 tttcaaaatt cctatttatc atattattag aaatacatct tcgaatatct atttccttac
      301 cttcaacttt aactccataa tatggcttag aaactaatat taaattatac tttgacaaaa
      361 taggctttat tctttttatg tcatttagta ttgtaaattt actcacatac aagctattag
      421 ctaaatcttc tagttttata tatgtattgt tatagagaat atattttaaa atatattgat
      481 ttctttctat aggagaatct ggtatttcac ttgaatccat aatatcatca gatattaatg
      541 ctagatactg ttggtataat gctaaattaa gaatatctat ataatatcct tctccttttt
      601 ttattttaat aatagcacca tttttctcta aagttccatt tatagaagta atatcatttc
      661 ttatagttct ctcactcact tttaaatgat tacttaaagt tttacaagta attttatcat
      721 cactttcatt taataattta aacaacgtga gcaatctctt gtgcataaat atcccccctt
      781 atagaatttc ttctaaatta tactatttac actcatataa tacaattact ctaataaaat
      841 tgtattataa taatttattt ccacttctat atggaaatta gttattatca taatataaat
      901 ttccatgtcg aagtggaaat tagttatatt taatttaatt aggataatga ttacaatata
      961 aatataagtt aagacattat gaatggagtg gaaaaatata tggtactaca agaaaaatat
     1021 atatttatag ataaagactt aaaaagcaaa gaagaagtat taaattttat tgcagatagt
     1081 gcttatatac taggtattac aactaataaa gaggctcttt taaaagacct tctaaaaaga
     1141 gaaaatgaat ttccaacagg aataaaagat ggatttgcga tacctcatac aaaaagtgta
     1201 aatgtaaagg aagcttccat actctatatt aaaacaacta acgagttaga gtggaaaact
     1261 ttagatgata gtaaggttag atatgtattt agtttgttag ccccacataa aaatgaagga
     1321 aatatacatt tgaaaactct atctaaatta gccacatgtt taatggagga tgattttaca
     1381 aatgaagtta aaaatgctag tgatgcaagt catttagtaa aatatataac taataaaatg
     1441 aaggaggaat aattatgaaa atagtagcaa taacatcatg tatagcagga ttagcacaca
     1501 cacctatggc agcaaaagct ttagaacaag ctgcatcaaa aatgggtcat gaaatcaaag
     1561 tagaacaaca aggtgctatg ggacgagtaa atactataac aaaagaagaa gcacaagatg
     1621 cggactttat acttatagca tctgaccaaa ctatatctgg aatggaaaga tttgatggta
     1681 aaaaggtgat aaaagtcaaa ataggtatag cgttaaaaaa accagaagct gtcttaacaa
     1741 agtgtataga agctatttct taataaaaaa atctcactct aatatagaat gagaaaaatc
     1801 aaaaattaaa aaattgtcta atgtaattat aacatattat caaaaaatat aacaaactta
     1861 tataggagga ttaaaaatga gtaaaaaaaa taaatctctt ttaagtgaac ttaagggaca
     1921 cttaatgaca ggtatctcat atatgttgcc acttgtaata ggctcatctt tagttgtagc
     1981 tatcccaaag cttacagctt tagcaatggg tataacaagt ttagatgctt ataaaaatgt
     2041 atctggtttt tatcatattc tttacttaat ggaacaagtt ggttggactg gcataggtct
     2101 attaaatacg gtattagcag gatttatagc attttcaata ggtgagaaac cagctatggg
     2161 tgcaggtttt attggtgggc tcatagcaag taatactaat gcaggattct taggagcagt
     2221 aatagcaggt ttctttgctg ggtatgtttg taagttttta aagaaaaaaa ttaaaatatc
     2281 tgggtcagca tcaggaatga tgccacttat aataatgcca cttataacag ttggattaac
     2341 tggtttttta atgagtgttg tattagcagg acctttagga aacataaata cttcattaaa
     2401 tgcttgggta gctgaaatgt gtcaaaatgg aacaaattcg gtggtattgg ctttaatttt
     2461 aggcgcaatg ataggattcg atttaggtgg accagtaaat aaagcagctt ggatggcagg
     2521 aaatgcatta ttgttagagg gaatctatct accagcgata ttggtaaact gcgcaatagt
     2581 tatacctcca ctaggatatg gtttagctac attcataaga aaatcaaagt tttccaatgc
     2641 attagctgaa acaggaaaag gcaatatagt tatgggtata attggaataa cagaaggtgc
     2701 aattcctttc actttaacaa atccattaaa attagttcct gttaatatga taggatgcgc
     2761 tttgggtgta ggattatcag ctttgttagg tgtacatgct ataatgcctc cagttggtgg
     2821 attatatgga tttatatcaa taggttctgg atgggcttac ttagtaggtg caatatttgg
     2881 agctttagta atagcaatat tatcaacaac tttagtagac ttcaatgaag atgaaactac
     2941 ggaaaataca gaatttgatg aaatagagtt agatataatg taaattaaaa acttaatttt
     3001 agataattga gaattgagtg tactctcaat tctcaattaa attttgggag gatttttatg
     3061 aaaaagacaa aagtacatgt agttccacac agtcattggg atagagaatg gtattttaca
     3121 acatcaaggt caaaaatata tttaatgaaa gattttcaag atatattaga catattggaa
     3181 gaaaaagaag actttaaata ctttactatg gatgcacaag cttctctctt agatgattat
     3241 ttaaaatgga gacctcagga tgaatataga ataagagatt tagttcaaag aagaagatta
     3301 gttattggac cttggtatac tcaaacagac caattggtta tatcaggaga atctataatt
     3361 agaaaccttt actatggaat agatagatgc aatgaatttg gtgaacctat gagggttgga
     3421 tatgtaccag attcttttgg gcaatcagct caaatgccac aaatatacag aggttttgga
     3481 atagatagtt cattattttg gcgtggagtt tctgatgata tggtagatac aacagagttt
     3541 atatggaaag gttctgatgg ttcaaaagta ttagcagttc aaataccatt tggttattac
     3601 tatggaggta atataccaga agatgattct gatttaaaag aatatttaaa agatataatc
     3661 ggaaaactta aggttaaagc ttctactaat aacgtatatt ttccaaatgg atttgaccaa
     3721 gcaccaataa gaaaaaacct tcctgatata ttaaaaaaag ctaatgaaat agataatgaa
     3781 aatgaatacg aaataagtga tatagaaaac tatatagatt cagtaagaaa tgaaagaaat
     3841 gaatttacag agcttaaagg tgaattttta aatgctaaac atatgagaat acacaaatcc
     3901 atattctcct caaggtcaga ccttaaaata atgaataaca aattagaaaa ttatattaca
     3961 aatgtacttg aaccattatt aacattaagt tattcacttg gaaatgaata ccctcaccta
     4021 gttataaaag atatatggaa acttatgttt gaaaatgcag ctcatgacag cataggttct
     4081 tgtaatagtg acacaacaaa tgaggatgta tacacaagat acaaacaagc cagagatttg
     4141 agtataaatt tattagattt gcatatgaga cttataagta ctcaaatcaa aaataataat
     4201 gaagaaataa cattaacagt attcaatgga ttcccagaag tcagaaatga agttgtagaa
     4261 tttgatactt atattccagg tcaagatttt gtgataaaga ataaaaatgg aaaaattctt
     4321 aattatataa taaaagaaaa agaagatatt acaaattata tattaactca aacaataaga
     4381 ttaaacccaa gtaaaaaaat atatataccc aaaactgtat atagagcaaa aattgcactt
     4441 tcagtaaaag atataccacc aatgggatat actcaactag tttttgaatt ggatactaaa
     4501 aataaatgtg aaatagaaac aagtaattgc aaggaaatag aaaacaaata ctacaaaata
     4561 acagccaata aaaatggttc attagaaata ttagataaag aatctaataa gacttataaa
     4621 aaccaagctg taattgaaga caatggagat gatggagatt catacaacta ttctcctcca
     4681 agaaaagata tttatgtttc atctttagat tctgtatctt cagtagaagt gctaaaatca
     4741 aacattcaag aagaaatgat acttaaatat tcattgacca taccaacttc actggaagaa
     4801 agggctatag gtaaagtttc tgtgaaaatg ccagtaacaa tgaaaatcac cttagaacct
     4861 aaagaacaaa taattaagtt taatgttaat ataaaaaata accaagcact atctcataga
     4921 gtaagagttt tatttaatac agaaatagca tctaagtttt ctatagcaga tcaacaattt
     4981 ggaataatac aaagaccaac agtattagaa aaagaccttg cattgtggaa aagagacaat
     5041 tactcatggc aagaaaaacc tataactatc gaaccaatgc aaagttttgt tactttagag
     5101 gatggacaaa gaggaatagc attaataact ggttgtgtaa gagaatatca aatagttggt
     5161 gataatttag atacaatagc attaacacta ttcaggtcat ttggatatat gggaagagaa
     5221 aatttacttt atagaccagg aagagcttct ggagaaaaaa taatagcaac accagatgca
     5281 caattactta aagagttaaa ctttgacttt ggtctttaca tatataacaa taaatttgat
     5341 gaagcaaatg tagctaatac agctaagaga ttcttaacac ctatacaaat atatgaatat
     5401 gctgattttt taaatggtag acttatattt gcattcaatg acgaaaaaca aatatatgaa
     5461 aatgaattta gtttgatgaa tgtaaataat tcaaatttca cagtaagtgc aataaagaaa
     5521 gaagaaaaag gagatggaat tgtagttaga atcttcaatg gtatgaaaaa tgaggatgct
     5581 aagggaagtc ttaacatcaa taaaaatgtc aatgatgctt atagtgcaat gctcgacgaa
     5641 atctatgata atactagcaa gcttaaagta aatactaaaa ctgtagaggt aaattcttta
     5701 tcacattgta aagtacaaac aatagtaatt aaataatata aaatagctta tacaagattt
     5761 caaaataaat tgctagtact atgttaatag taaagccaga tattatgcta tttataagct
     5821 ctgtaacact aaataacatt ttgtaaaata aaaaggtgaa ccttgtatat taggattcac
     5881 cttttttaaa taaatcaaca ttctgtttta aaataacatt tataagctgt tttgaaataa
     5941 tgcttacaaa ttattttaaa acaataccta taaattttta tttaaagaat acacataaat
     6001 atttccagat tcttttattc tatagacttt ataattatta aagaagtcta atctaatttt
     6061 tgttaaaagt aattgtaact ttgaataaat caccatccac acttatattc atcttaccac
     6121 cctgtaattc tataaaactt tttgctatcg ctaaaccaag accagaacct tctgtgttac
     6181 gtgatttatc tcctcttaca aatctctcca ttatatcatc tacactaaaa tcaatctcag
     6241 atgcagacat atttttaagc ataatattta ctttattatc tgtttctaaa atatcaatat
     6301 acactcttga atttggcatt gcatatttgc ttatatttat tataagattt tcaaatactc
     6361 taaatgtacg ctgactatct aatggtaata ttattttttc attagaaaag ttattcttta
     6421 ctattagaga tgaatctgca agtttgtcat ctaattctaa aagtgtctgc ttcattagag
     6481 atacaatatc cacatttact atattcaaat aaacatctcc actatttgcc ttgcttactt
     6541 caaacaaatc ttctattaga tgttgcaatc tttgtgactt tctgtctaat gtatcaatat
     6601 acaacttacg attttcatct gttatacttt catcttttaa taaatctata taagtgatta
     6661 tagatgttag aggtgttttt aagtcatgtg atacatttga tataagctct gttttcatct
     6721 tttgactctt aacctcttcg tcaacagctt ttttaaatcc agtttgaata tttcctaatt
     6781 catcttttat aggattaaaa aatcctaaat ctttttccat atttacatct aagtttccat
     6841 ctgaaatttt ctttgtaaca tctaaaagtt gattatattc atatattgtc tttttagagt
     6901 aatctgacag tatcttaaat aatactactg aatatattaa tgcgagtatt attccaaaga
     6961 accacatact acacattata actataatca ataaatttat tcccaaaatt gtaactatag
     7021 ttttatttgg cttttctttc agatttattg ttctaatttg attaataact gcttttcctg
     7081 ctttttttaa ccatacaaaa aacattcctg tcacagtatg ttttgtaaaa tactctctta
     7141 ttccaacatt taaaatgtgt tttaaaagta ttataaatac aaatattatt gagaatatta
     7201 caaaccaata agttaaattc attaaactta ccaatatact agccatttta gcacttatgt
     7261 cattgtttat aaggtactct acataattcc cactcaaggt attacttatt ataacagtag
     7321 gatataaatc tacaagcccc tgtataatag caagagcaat aaagagtatc tctaacggta
     7381 ttcttgataa tgtatcaaat cctagcaact ctttagattt tctatatggg aatgctaaag
     7441 ctacaataac aactatagct aatataattt ttaaaatcat tccagaaatc ttataataag
     7501 aattattttc tacattgctt atatatgaaa ttataccatc atcaaaataa gtatttccat
     7561 aaccatactc tacactatca cctttactta ttactttagg tacagcatat actaatgtta
     7621 tattttttat tggagataac ttatatgaaa ttgaatttcc tcctaaactt gtatccatta
     7681 aatcttctct tgctttagat aacaacattt gattaataat tttttgattt actccataag
     7741 aatccacaat atttactttt ccatctttat caaaattcat tacaacgtag aatctatagt
     7801 tttcttttat atctgtaatc tgcttttgtc tttcctcatc attcatttct gtattttttg
     7861 actgattttc attagaattt tcttttgaag catcattttt tgttgtatca agtactccta
     7921 attctttatt atcattaaaa aattcaaaat tgctttcttt atcaactaaa tagtacttta
     7981 aattctttcc tgacgcttta atgaaatgct cccaattttc aaagttttca ttaaaatctg
     8041 cattaatact atcatctgta taataagttt ctgaaccatc ataagtatct ttttctttac
     8101 ttacattttt tatatagttc atagtttctt cattgataaa tagctttgat ggttgtatca
     8161 tcttaccttc ttgttcttcc ttcatattat gatataaaac ataacttcct ttatatatac
     8221 tatctacaaa gctttcctgt tcaaatggat tctctgctcc acctttagca cttgcttgta
     8281 tagtagaata ttgactaatc atacctaatg atgctgataa cataagtata aaaactataa
     8341 tagtaactat atatttatct ttaaattttt tcaattttgt atccaacacc ccacaccacc
     8401 tttaaatatt taggattttt tgggtcaatt tctatctttt cccttatatt cctcacatgt
     8461 accataactg tatctgtatt tacagcattc tcattccaaa ctctttcata tatttcatca
     8521 gcagaaaaaa ctcttcctgc atttctcata agtaaactta gtattttaaa ttctatagga
     8581 gttgttttta tatactttcc atcaatacta acttcttttg tattttcatt taattctaat
     8641 ccgcctattg caaacacact atcgtcactt tctacctttt gctctttatt tccaaccatg
     8701 tttagatact tagtgtacct tctaagttgt gaattaactc tagccaatag ttctaatggc
     8761 ttaaaaggtt ttgttacata atcgtctgct cctatattaa gccccattat tttgtcaact
     8821 tcttctgatt ttgcagatag cattattact ggaaaattat agttttctct aagcttcatt
     8881 gtaagtgtta taccatccat tttaggcatc attatatcaa ctatagctaa atgtatttct
     8941 tggttttcta taaccttaag accttctaat ccattgtatc ccttaaaaac attatatcct
     9001 tgatttaata gatatatttc tatagcatct gctatctcct tttcatcttc taccaccaaa
     9061 atattatatg aattcattct aatctccttt atattaattt ataaattttc tttacatata
     9121 tgattataca atatgataga agtttttcca tttatatata tatttatatc ttttgttctg
     9181 gttatttgta tttaatgtcc atcttagaaa cctccttcta gtttaaattt aatatttttt
     9241 cattttgttt tatatactta atattaaaat taaaaactta agatattaca tatacttttc
     9301 taaagatttt ctaaagattt aaatatattt aaaattaata tacaaaaaaa agtagttctt
     9361 attgtattaa ttaaattaat gatttgaaat ataaaattaa tatcaataaa acctactttt
     9421 taatttttta aatatttatt tttaatttat tttgttttta atttacttcg attttaaaat
     9481 gtccttgact tttattttat aaatgtacat atttcttcta ctggtttttt agatggactc
     9541 ttcaaattgt cctctggcac tccaagagct aacattgcac ctaaaaaata ctctcccttt
     9601 tcaaaaccag tttctgcttc taaaacagct tctatctcat ctgctgcata gttttgactt
     9661 gtcaaccaac aagaaccata tccaagttca attgctgata gtgtaaagtt ttcaattgca
     9721 gcacctagac tctgcatacc tggatttctt ataaataatt tatctatagt ctccttaggt
     9781 gcatctataa gctctaattc ataatatcct gatggattat atacctttgt aaaaactaat
     9841 actaaaactg gagcttttaa gtaaaatagt gtaaaatttt taacaaattt tctaaatcta
     9901 ttagccttat ccactgatac tttatccatt tctacaagta tttcttgttg ctttttagtt
     9961 atcacatctg ctatcttttc cattaaatca cggcgtttta taacaacaaa atgccagttt
    10021 tgaatattct tgcctgatgg tgctgcacct gctgctttta tcatttttaa aatatcttca
    10081 tctgatacat cttgattttt aaactttctt acactttgtc ttttaaaaat agtatcttgt
    10141 aattccattt ttaaatcccc ccataacttt tttattattt taatataatt tttaaactca
    10201 tcttatttta atatatcatg ttctaacaaa tctttaaatg aatctataaa ataatcatat
    10261 acatctacat tcccaaaccc atatttggca tatataaaag gtatacctac aaacttagca
    10321 ctatttgcat caccttgcgt atcaccaaca tagattggat ttattaattt atttctttca
    10381 attataagtt tattattttc tcctttatgc aaaccagtat taccaggaca ttcaaaatct
    10441 ataaaatact gttctagttt atgtgctttt aaaaaagatt ctatatatcc agcttgacaa
    10501 ttacttacta taaataattt atatttttta gatagtaatt taagagtatc ttctatatca
    10561 tcaaataatt tagctccatt ttcagataaa tagtcacatt ctttcaaaga acattcattc
    10621 aataaattca ttctttcttc ttcacttaaa tttggaaata aacgatttgc tatttcctca
    10681 aaagaaagcc ccataagact tctaaataaa tcttttgtga cacttaattc tatttcctta
    10741 tgctcactta aaacatcctg ccagactttg catacttctt cagttgaatc ccacaatgtt
    10801 ccatctaaat caaaaataat actatctacc acaaaaaatc ccccttatgt caaagtttat
    10861 tatatattta taattatata ctaaaaagca gatacaatca taaatatatt ttacttgatt
    10921 gtatctgctc tacaatataa aaccaattgt caaaatcaaa ttttataaat ttctaactac
    10981 aagtacacag ccttgctcta ctttaatctt acaagaatta ctcaacataa catttgatat
    11041 tccaataggt acagagtatt tcatataata attatcgaga gggtattcta agccagtaag
    11101 tgttacaccc ttagcatcac catttatagc tattacagaa atagtgtccc ctgggtttcc
    11161 atacaatgaa atttcctcat tttcaactat atacatctct tctttatcag aaagtatcct
    11221 agaatatata ccatcttctt ttaaataata taatagcttt atatttgcaa gagtgtggtc
    11281 aatccttccc cctaaagcac caaaaaaatc aatatgattt gctttaagtg tcttagctaa
    11341 aaaaagacaa agctctgtat cagtctcatc ttttttagat ggaaattttt caaatttaac
    11401 acctttattt ttatagaagt ttatcttttc ttcttctact gaatctaaat ctcctaatat
    11461 ataatctggc attatttcca ttttataagt gtgatttgcc cctccatctg cacatattat
    11521 gcagtcataa cattccttaa ttataatatc tcttgtaact tcgtaatctt caatttcgcc
    11581 atttaaaaca atacagattt tcattattaa atttaaacta attcttcaag agaagcattc
    11641 tttctaaata aattaactgt ttcttgaatg tcatcacttc caaatattgc agaacctgct
    11701 actattacat tagctcctgc ttgtacaact tcggctacgt ttttagggct tataccacca
    11761 tcaacttcta tatcaatgtt taatccttga ctatctataa tagcttttaa ctctttaatc
    11821 ttatctaaaa cacaaggaat aaatgattgt cctccaaatc cagggttaac agacattaat
    11881 aataccatat ctaaatcaga tagtacatgt ttaatcgtat ctactggtgt agctggatta
    11941 agtactacac cagcttttat tccatgtgat tttatatttt gtatagttct atgtagatga
    12001 acacaagcct cctggtgaac agttattata tcacatcctg cttttacaaa ttcttcaata
    12061 tactggtctg gattttctat cataagatga gcatcaaata ccatatttat attttctttc
    12121 tttaaacttt tgactacaag tggtcctaat gtaatgtttg gtacaaagtg tccatccatt
    12181 acatcgatat gaagatattc acatcctgca ctttctactt ttcttacatc ttctaataat
    12241 tttgcaaaat ctgctgataa tattgatggt gctaatttaa tcatgtttct aatacctcct
    12301 actattattt tgtcttattt catgtagcag ctgtatataa ctatcatatc tttctttaga
    12361 tatttctcca tttgtaacag cttcttttat agcacaatta ggttcatttt catgaataca
    12421 ctttgaacca aacttacaat cattaaattt atcaaattct ataaaataat ctttaagttc
    12481 aacttcctct atatcttcaa gtgcaaggga actaaaacct ggtgtatctg caaccattcc
    12541 accaaattct aattttaaaa gttcagcgtg acgagtagta tgttttcccc tttttatttt
    12601 atcacttaca actcctgttt gaagtttaaa attttcatct atttcattta ataagcttga
    12661 ttttccaact ccagatggtc ctgcaaacac tactacattt tcttttaatt cttcttttac
    12721 tttatctata tttaacttag taatattgct tacaggaatg actttataac cactaagttc
    12781 atatatattt ttaacagttt ctaatgtatc attatcatct aaatctgctt ttgtaaggat
    12841 tattacagtt tctaaatttt ctttttctgc caaaactata aatctatcta aaagagataa
    12901 gtttggttta ggatttttta ttgcgaatac tattaatgct ttatctacat ttgcaatagg
    12961 aggtcttata agttctgtat ctctactgtc gatttcttct aagataccct ttttttcatc
    13021 ttcatcaaca atgcttattt tgactctatc accaaccaaa ggtgttattt tctgctttct
    13081 aaatatccct ctagccttac attcataaat accattataa gtatctacat aataaaatcc
    13141 actaatcccc tttataattt ttccttctag catcaaatgc ctccctttat aaaatttata
    13201 taaacacata ctgtttatga gtagtatatc gtgttattct ttcctatttt tatataatac
    13261 cacatttttt ttaaataaca aatcctccgt ttggactaat tacctgacca gtgataaaat
    13321 ttgatttgtc tgatgccaag aaaatagcac aatttgctat atcttctgga gttcctagcc
    13381 tcattagagg ggtttcttcc acaagagcgt ctatatcttc ctcattatat ccagataaca
    13441 tgtcagtatt aatgacacct ggagctatgc tatttactct aatatttgat ggtcctactt
    13501 ctttagctaa tgcctttgtc atacctatta tacctgcttt tgttatagaa taatgcactt
    13561 cacaagacgc acctgatata ccccagattg aagatatatt aattatattt cctttttttt
    13621 ctgatatcat gtattttaaa gcaacttgtg aacaataaaa gcttcctttt aaattaatat
    13681 tcatcatatt atcccaatct tcatcagtta tatctgtaaa caacttatct tgacttacac
    13741 cagcattgtt tacaagtaca tccaatcctc caaattcttt tatacaataa tctaccatat
    13801 cctctacatc ttctctattt gaaatattag ccttaaaaag ttttacagaa aaattttttt
    13861 catttaatat agtgtacaac tctttagctt cattttctga cttattaaaa tttactaata
    13921 cattgtaacc ttcttttgca aaagctttag acatagcttt accaatccct ctagctcctc
    13981 ctgtaattaa aactgttttc ttcttcataa atacttttct ccttatatta taaccaattc
    14041 agtattttat acaaaacaaa ctgcccttta aagaaaatat tttctataaa aggacagctc
    14101 ttattttatt aatatttatt ctgttttacc aatgtttgcg ccagttcctg atgaagttcc
    14161 tccattatct cctgagtttg agcctcctga actatctcca ttgtctcctg agtttgaacc
    14221 tcctgaactt cctccattgt ctcctgagtt tgagcctcct gaacttcctc cattatctcc
    14281 tgagtttgag cctcctgagt ttccaccact atttcctgag tttgaacctc ctgagttact
    14341 tccattattg cctgagtttc caccactatt tcctgaattt gagcctcctg aatttccacc
    14401 actgtttcct gagtttgaac caggttctgt tggtgtatta ttctctggtg ttgttggttt
    14461 tttatctggt actgttggag tctgtgtatt tgatttttct gaacctttgc ttacatatag
    14521 atttacctca tcaccttcct gagctcttga tgagccagca cctggactct gacttaaaac
    14581 tgtaccttct ttatatattg agctgtattc atacttaaca gttcccactt ttaagttatt
    14641 ttcttcaata agttgttttg cattactcaa agtaagtccc actacattag gaacagatgc
    14701 ctgacttgaa cctttactta cgacaacatt tatagtatca ccctttttga catttgtact
    14761 tccaccttca ggtgtctgtg atattataca attttcatca acttcactat tatactcttc
    14821 actttttaca ctcaggtata atccttcttt ttcaacagca ctttgagctt cttctaatgt
    14881 catatttaca agattaggaa cagtcaaaga tttattgcca aaccctccag caaataaaaa
    14941 cttatatgct aagaatactt gagcacacaa tatcagtatc aaaacagccg caattacttt
    15001 taatcttctt ctagattttg ggctttcctg ttttttcttc tttttcttag ttctcttact
    15061 tggagtactc ttaggtctct gattcttttt agctctcatt atctcttcct cttcttcatc
    15121 ttcatcatca tcttcttcat aaaaatcatc atagtaatct tcatcatcat ccaaatcagc
    15181 tacttcaaca ggcttaacca ctttttcagg agctggtttt gcaagtgttg gatttacaac
    15241 tttattaatt tctttttcat caattttctt agttgcaaaa tcatcatatt cttttataaa
    15301 atctaaatca atattttttt ctatatactc tatatcttct atcaattctt cagcagtttg
    15361 atatctatct gcactagatt tttctgtaag cttttttatt gtagttctta cactttgagg
    15421 aatcctaact ttttcttctg atgtaaagtc tatatcatca ttaatgtgtt gaagtgctat
    15481 agaaattgga ctatctcccc taaatggaac ttttcctatc aacatttcat ataaaactat
    15541 acctagagaa tacaggtcag cattattagt tacaaattta cctttagctt gctctggtga
    15601 aaaataatgc actgaaccta ttatactacc aatattagtc attgttgaat ttgaaacagc
    15661 tttggctata ccaaaatcag ccacttttac tactcttcct tcatttgata tgagaatatt
    15721 atgaggtttt atatctctat gtataatccc ctttttgtgc gctgcactaa gtgccatagc
    15781 tatttgtttt gttatatcta atgcagtata ttcatctaat ataccttcat cttgtataat
    15841 ctcttttaga ttcttcccat ctacaaactc cattacaatg tagtgaactt ttccatcttc
    15901 accaacatca taaacattta ctatatttgg atgtgaaaga cttgctactg cttctgcctc
    15961 tcttttaaac tttgttagaa attcatcatc atctacaaat tcaggtctaa gtactttaag
    16021 tgcaacagtc ctgtttaata atctgtcttt agcctcatat acaaatgcca ttcctccatc
    16081 accaatcttc ctgatgattt catatcgatt tcctaaaatt gtatctccca caatatcacc
    16141 gtcctaatta tacttttatc actataaccg aaacattatc tttaccagaa acatcattgg
    16201 ccatacttat caattcttca cttatattac tagttctctc atattcataa tctaatatta
    16261 aatctcttat atcttcatca tcaataaacc cagttaatcc atctgtcgca agaagtatta
    16321 tatcactttt tttgatttct ttcttaaaaa tatctacaac aaccatatca tctgttccaa
    16381 ttgctctagt tattctattc ctctgtggat gtcttcttgc ctcttcttct gtaatgacat
    16441 gggccatcat aagttcttca accacggaat ggtctatagt tattttatca aatttttcat
    16501 ctgttaacaa ataacatctg ctatctccaa catttgccac atataagaca ttattataca
    16561 ctatagccgt aactaatgta gttcccattc cttcaaattc tatatcttcc atagattttt
    16621 tgtgcacaat tgagtttaca ttattataag cctgttttaa tatatcatct atatagtcta
    16681 tttttacatt atcatgttgt aataagtttt cctttagaaa atcaattata ttttctactg
    16741 ctaatttact ggcgacttca ccttttttat gtccacccat tccatcagct atggcaaata
    16801 ttcctattgg accatgttct gtatctataa cttctccctc acaatagtct tcattgtttt
    16861 ttcttatttt tcctatatgg gaggcacaac tataaaccat acgacttcct ccttacaaat
    16921 tacttgtatt ttcttctcaa ttgcccacaa gctccactaa tatcagaacc catagacatc
    16981 ctaactgtgg caggtatatt gttcttctcc aaactatccc taaatttata aataaatgct
    17041 ttatctggct tttcatattc tctttcttca actttattta ttggaattaa atttacatga
    17101 catagcatac cttttaggag cttagctaat gcctttgctt ctttttctga gtcatttacc
    17161 ccttttataa gagaatattc aaatgtaacc cttctatttg tcttttttat ataatatcta
    17221 catgcattca atatttcttc aatagaataa gcatttgcta caggcataat ttttcttcgt
    17281 tcttcatcat atggtgaatg aagtgataaa gctaaattta tagctatttc taagtctgcc
    17341 aactcataca ttttaggtac tattccacaa gttgaaagag ttatatgcct ataccctata
    17401 ttaagaccat ttttttcgtt aattattttt aaaaattgtt ttgtattttc aaagttatca
    17461 agtggctcac cactccccat caatacaaga tttgataccc tcttaccagt atcttcttga
    17521 attttaataa cttggtctaa aatttcccat ggctctaagt ttctaattaa tccatccatt
    17581 gtagatgcac aaaaattaca tcccatccta caacctactt ggttagaaac acagacagta
    17641 actctactat cataatccat catcacagtt tctattatat ttccatcatc taataaaaac
    17701 aaatattttt ttgtattatc taccttagat tctaacttta attctatatc tatatgccct
    17761 atacatgaaa cctcttctaa tttatttctc aaactttttg gtatattgtt catatcatca
    17821 aaagtttttg cacccttata tatccaagag aatatttgac ttcctctaaa gggcttttca
    17881 tctatagttt tcataaattc tttaagttca tcttcagtaa aattttttaa tactatcttt
    17941 ttcttttcca ttctctcact accttattct ctttaatttt gctatgaaaa aaccatctat
    18001 accatgaata ttaggatata tctttaaata tcctttatct tgattgtcta agtctacatt
    18061 tactgtatca attggaacaa attcaaagtt gtgattttct tcaacaaaag aagtaactat
    18121 atttatattc tccacatctt gaattgtaca tgtactatat actaaagttc caccaacttt
    18181 gacatattta gatgcatttt ctaaaatttt cttttgtata gaagtgatgt cttttaactc
    18241 ttcttctttc ttatacttaa tttctggttt acgtcttatt ataccaaaac cagagcaagg
    18301 aacatctgct aaaacataat caaatttact tatactattt tcatcaatct cagaagcatc
    18361 aaatctttct acaaacacat ttttaagccc caatctattt acagtagagt ttataagctt
    18421 tagtttatgc tcaaaaatat ctctagctac tacttgacca gtattgttca ttaaagtagc
    18481 taagtgagta gatttccctc caggagcact acatacatcc aaaacaaatg agccttcttt
    18541 tggattaatt actttcccta ctatcataga acttatatct tgaattgtaa ataaaccagc
    18601 cttaaataat tcattttttt ctatattttt cattttttcg actttaatag cttcttctac
    18661 cataggaact tttaaacata caatacccat ttcacttaat ttttcaataa gttcttctct
    18721 acttatttta agtgtattcg ttcttatata gatactaggc ttttcattat ttgcttccaa
    18781 caaatcttca gcaaattctt gtccaaattt atctatccag ttttttataa tccaagagtt
    18841 ataggaatac tttatagata agtattttac actatcttcc tcagttatgt ccattatagt
    18901 ctctttagct cttatttcat ttctaagaat agcatttatg aaaccagaag attttttatc
    18961 atatttctta gataatttta cagtttcatt aactgctgca taatctgata tactatctaa
    19021 aaataaaatc tgatatgttc ccattcttaa aaagatttta acataagttg acattttttt
    19081 tacctttatt tttgaaagtt tattgattat ataatctaaa taatatttat tttctattac
    19141 tccataaatt aactctgttg caagtcctct atccatatca cttatttcta aatttttaaa
    19201 atgcttattt attgcaatat ttgaataatt gtcatttttt tctatatcac ataatacttt
    19261 aaatccaact tctcttgcat ccatataaat ttctcccttt tattaaacat aaaaaagggt
    19321 tgtttctaaa caacccactt tacttttagt catttcttct ttgagctatt agtaacaatc
    19381 taagtaattg aagtattgaa accaatgctg ctgcaacata tgttaaagct gctgctgaaa
    19441 gtactcttct actttgtctt gactcacttt catctataat acctaaattc ccaagttgaa
    19501 cgattgctct acttgaagca ttaaattcta caggcaatgt tattatttgg aataacactg
    19561 aagccgaaaa caatagtata ccaattttta aaaatggacc agccataata aatcctaaaa
    19621 atattaaaaa ccaagatata cttgaagcaa aattcactac tggtactaaa ctacttctta
    19681 tttgaagagg tgcataacct ttagcatgtt gtatggcatg accacattca tgtgcagcta
    19741 ctgcaacaga agttatagat gttccataat atacatcttc tgacaacctt acagcctttc
    19801 ttcttgggtc ataatggtca cttagatgcc ctctaaccat ttctatcttt acatcataca
    19861 aaccatttga atcaagtact cttcttgctg tttgctctcc agtatatcct cgacgtgtat
    19921 ttactcttaa atacttattt gttgttgaac tcactttaaa ttgtgcatat atagtaagta
    19981 atatagctgg aattaataca accattgttg ggtcaaatcc ccaaaaaccg ccatatacag
    20041 ggtacataaa taacactctc ctaaaatata tttttattat acatcctctt aatattcact
    20101 taacttaaaa acagtttaat tacaaactaa tatatttttt cctgttaaaa agcctatagc
    20161 tttttcaata tccatcatgt ctacattagt atttacacaa ggtccattag gtcttttgtt
    20221 aaatacacct aaaacaggaa ttttcttaat atcttgtatt ccagatgtca aatctctttc
    20281 acatgcaaca gctacaacag ctttaggttt agtgtccatt ataatttttc tagctagagt
    20341 tcctcctgta gctacaaata tttttacatt agttttttcc tttagcttaa ttaattctcc
    20401 tatgttgcat cttccacatt ctttacaatt atctatatca ttagtaactt ttaatttaca
    20461 actattctct tgaatacaat gaggtattaa aattattata tcctctggat taaaattata
    20521 tttattactg tatatatatt cattatttaa ctttatatat attcttctaa tatcactttt
    20581 tgacatacca aatgatgatg caatgaaaga tataatagga aataatccac tgacaatatt
    20641 aaaatttatt ttcattatat ttgagttaac atactttcct ttaattactc tataagtaac
    20701 tactgttgaa catagtatta taagtattag tgatattatt ataatattta tcatcaagga
    20761 gaatatttga gttaaactta ttataaaaaa attaacaact cctatcaaaa ttcctaatat
    20821 taaaatcaaa atcccaacac ttgttaaata cttctttata tctgtcatac ttttcaccta
    20881 acccaatact aaaccagttt ctatagtatt cccttttata tattcaccaa ccaacattct
    20941 ctttttattc ggcatctgaa tttcttcaat taaaagtaca ttatctatag tacttacttt
    21001 tatcccatct ttgcttacat caattattgt acctacatct tttgtgcttt tttcatctaa
    21061 cactttagtt ttccaaactt tcattatgac atcattatag gtagtataag cacttggcca
    21121 tggatttact cctctaacta aattgtgtat ttctctggca ctttttgaaa aatctatgtt
    21181 acctaatgat ttattcatta ttggcgcata ggaaaattct tcatgatttt gtacttctct
    21241 tggagcattt ccttcttcaa ttaatcttaa tgtttctttt aaagtttctg ctcctatatt
    21301 catcatttta tcatgaagtt ctcctgctgt tatattttca tcaagattta cttctgtctt
    21361 tagtatcata tctccagtat ctaatccttc atccatatac atagttgtaa caccagtctt
    21421 ttcttcacca tttattatta cccaatttat aggtgccgca cctctatatt ttggaagtaa
    21481 agaaacatga acatttatac atccaagttt aggaatctct aatatttctt ttggaagtat
    21541 ctgtccaaaa gctacaacta ctattacatc tggatttaaa gatttaattt tatctataaa
    21601 ttctttatct ctagccttta ctggttgata tacaggtata ttattttcaa ttgccagttc
    21661 ttttactgga ctcataccta gttttttacc tcttcctttt ggtttatctg gttgagttac
    21721 aacacccaat atttcatact tctcatctat tattttttgt aaacatggaa ctgctatatc
    21781 aggagttccc ataaatacta ttttcatcaa atcaactcct actacttttc tattttgtca
    21841 acaaataaaa ttccatctaa gtggtctatc tcatgacaaa atgctctagc taaaagttct
    21901 tctccctcta actctattgt ttcaccattt ctatttaaag ctctgacctt tacataattt
    21961 ggtcttctaa catttcccgc ttctccaaca acacttaaac atccttcctc atctatttgc
    22021 tccccagatg tttctattat ttcaggattt ataagttcta taagctcttc tccaatatct
    22081 attactacta ctctttttaa tattccaact tgaggtgcag ccagtccaac accatctgca
    22141 tcatacatag tttctgccat atcatctaat aattgtatta tcttttcatc aattttttca
    22201 accttttttg atttttttct taatactggt tctcctattt gaactatttg tcttaaagcc
    22261 attataattc ctcctaaatt tataatacac tgtttggatt aatatctata gatacattga
    22321 tattcttatc aaatatcaaa tctcgttttg ttatacatat atattttatt atacccttta
    22381 agagattaat ttcaatattt tcatctttaa agagtatttg ccatctataa ttttgattta
    22441 tttttgatat tgaacatgga tttggaccta atataaatcc taaatcattt ataccccttt
    22501 tttctaataa ataaatcaat gatgcatgca tattttttat attttttatc actaatcttt
    22561 catcttcacc actaacaact acacttaaca tattattaaa aggagaatat ccaaatgctt
    22621 ttcttatttt tatctcatct tcataaaaac cctcataatc atattcaata gcatgcttaa
    22681 tagcatagtg ttcagtgtca taagtctgaa gtactacttt tccctcttta tcagctctcc
    22741 ctgctcttcc agagacttga gttatcaatt gaaatgtagt ttcaaaactt ttaaagtctg
    22801 gaaaatttaa tatcatgtct gcagacaaaa tacctactaa agttacattc tcaaaatcca
    22861 gccctttact taacatctgt gttccaataa gtacatctgc ttctttatct ttaaatttat
    22921 ttagtatctc atctaaagca cctttttttg aagttgtatc tttatccatt ctcaaagttt
    22981 ttatatctgg aaaaatatat tttaattcct cttcaatttt ttgagttcca actccaaatg
    23041 gcttaacata agtactttta cattcaggac actcttttgg aatttctttc tcatatccac
    23101 aatagtggca tcttccagta ttgcttttct tatgataagt taaagatata tcacaatttt
    23161 cacattgaaa cacatatcca cactttctac aagatacaaa atttgcataa cctcttctgt
    23221 ttaaaaatag tattacttga ttattttctt caatcgcata acgtatttct ttttgtaatt
    23281 tcaaactaaa tatacttcta tttcctttat ctaactcatc tttcatgtct acaacttcaa
    23341 tgtttggaag aggcttatca tttgctctac tttttatatt tataagtttg tattctccag
    23401 attttgccct ataatactct tcaattgagg gcgttgctga acctaaaata agagttatat
    23461 tattttttaa tgccataaat ctagcaactt ctatagcatt aaattttgga ttcttctcag
    23521 acttatatga tgactcatga cattcatcaa ttattattaa gcctaaggaa ttaaaaggtg
    23581 caaataaagc tgacctagct ccaattaaca ctcttacttt acctgctttg acagctttgt
    23641 aaacgtcatg tttttctcct tcagatagtt tactgtggaa cactccaact aaatctccaa
    23701 acctactctt tagcctatct attgtttgag gagttaatgc tatctcaggt actaagaata
    23761 tactgtctaa gccttgattt agagcaaatt ctattatttc catgtaaact tcagtttttc
    23821 cacttccagt tactccatga attaagtatg gttttttatc atctacaaac atattcgact
    23881 ttatctcatc aactgcttct tgttgctcat tgtttaattt tatacttttt agtacggatt
    23941 tgtaaatact ttttggctct ctataataat ccttaaattc tagggttatt agctttttct
    24001 tacttagaga atttatactt tgttttgaag catttaataa atccaataaa tcatttatct
    24061 ctacattttc attattttta agaaaactta atatctcttt ttgtttactt cccacattta
    24121 ttttattttg ctctatataa tcgtcaatct tatcactttc taaactcaaa gatatataac
    24181 atactttctt ttcatttttg tgatttttat attcccaaca taattttata attccatttt
    24241 tattcattgt gtacaaagaa ctatttaagt ttggtatata ttttaactta tcaaccttaa
    24301 ttttaccttt actatcaatc actttctcta ctatttctct atttttatca cttaaagttg
    24361 atattttttc cttcaattca atatcattta atccacttaa actttcacct aataggacta
    24421 ctttataatt atttaatttg tatccctttg gatatatcaa atttatacat tctatataag
    24481 tacacaaata tctatttttc atccaataaa ccaactctaa atcttctttt ctaaatatcg
    24541 gattttcatc taatatatca ataatttctt ttatttttat tttttcatct aagctatctg
    24601 taaattgaaa tacaaaggct tctgttggtt tattaccttt tccaaatggt actaatattc
    24661 tgtgcccaat ttttattaca tcagataaaa atacaggaat ttgatatgta aataaattat
    24721 ctgtatatat agtattactt ctaactatta cctttgcata ttttttcatt ataaaacctc
    24781 tacttaaatt taatatattg ttcatatttt aatatacttt acaagatatt aaaatctcag
    24841 aatttataag caatttcaag ttattaatat taactttatt ttaataatta actattaatt
    24901 atattttata ctttatgaca aaataaatgc tgaaaactac aatttaactg acatttgcga
    24961 gtttttactc gctaaaatta aattgcagct ttcagccact ttagctgtga taaaatacac
    25021 aaatatcata tttaaaaaag gtcttatttc tcaagcaacg ctttaacttt atctaaaata
    25081 acattggcta cttcttcttt tttcatctta ggatactcag taatatttcc ctctacatct
    25141 attattttta caatattagt atcagctcta aaaccagcac cttctttagt taaatcattt
    25201 gccacaataa aatctaaatt tttctttttt atttttcctt tggcatgttc tataaggtca
    25261 ttagtttcag ctgcaaatcc aattagtatc ttatcttctt ttatttttcc tatttcataa
    25321 gcaatatcat aatttctact tagttctatt gataaatcat cattcttctt tttaattttt
    25381 ttgtcagaat aagtttttgg tttataatct gcaactgctg cactttgaat tactatttta
    25441 ttttcactta aatttgatac tactgcttca tacaaatctt gtgctgactc tatttgaaca
    25501 aattttttaa gattttgtgg aatagaaaga tttgtaggac ctgatattaa tgttacatca
    25561 gcacctctag ctatagcttc tcttgctata gaatatccca ttttaccaga agacctatta
    25621 gttaaatatc ttactgggtc tatactctct acagttggac cagctgtaac tatcatactt
    25681 tgacctttta aatcttgctc tttagtaaga ttagtcaaaa cttcctctac tattatatct
    25741 ggattagcta gtttacctgt tccaatatct ccacatgcaa gccttccact ttccggttca
    25801 ataaatttat atccaaagct ctttaaagtt tgtatatttt tttgaacaat tggattttca
    25861 tacatattag tattcatagc tggtgctata agaacctgtg cttttgttgc cataacagta
    25921 gttgtcaaca tatcgtcagc tataccattt gcaatcttgc ctataacatt tgcacttgct
    25981 ggcactatta agaataaatc tgcttttttt gctaatgata tatgttcaac ttcccaagtt
    26041 tttggttctt caaacatatc ttctactaca taattttgac tcagcgattg aaatgtaagt
    26101 ggtttaacaa attctgttgc tgattttgtc attataacat ggatatttgc atttagtttt
    26161 tttaacttac ttacaacatc acaagcctta tatgcagcta taccgccact tatgccaatt
    26221 acaacagttt tatcttttag catgacctta ctcctcttct gaaatttgtt ggtgttgctc
    26281 agcatgatgt ctagcttctt ctatctctat ttcctcttct gtcaataatc tatatgttat
    26341 ttttccactt gcaacttctt tagttgctac acatacaggc ttttccttag ttttatttga
    26401 aacatatggt tcttctccat caattaattt tcttgctctc tttgaaacag tccccactaa
    26461 atagtatctg ttgtctattt tttctagtac ctcattgata gatggtttta acataattat
    26521 aattcctcct taaatttctc tattataata tttttatatc tgctaacttt attcttttca
    26581 gatgatatta taccttctat ttctttagca gatgttttta catcttcatt aaatataaaa
    26641 taatcataat ccttaatcat tttaatttct tcatatgcac agctaaatct cttctctatt
    26701 tcagcttctg tttctgtacc tcttccaaca attctatttt ttaattcttc aagtgatggt
    26761 ggtagtacaa atataaatac tccctctggg caaacttctt ttatttgttt tgctccttgc
    26821 atttcaatct ccagtaatac atcttgtcct ttttctaaac attccattat tgccgctttt
    26881 ggagttccat aaaaattatc ataaatttga gcatactcca aaaactcacc tttttctatc
    26941 atctcttcaa acttttcctt acttatgaag aaataattta ctccatcaac ttctccagtt
    27001 ctgggttttc ttgtagtagc tgatacagaa agttttattg tatcattttc tttaagtagt
    27061 tctttgcaaa tagtaccttt tcctgcacct gatggtcctg atacaactag caataatcct
    27121 tttttcacaa acatttaagc attccccttc taatattgta ttcttactct atattttgta
    27181 tttgttctct tattttttcc aattcgcttt ttacttctac tactaaatta gttatattta
    27241 tatcagatga cttcgaacct atagtgttag tttctctatt catctcttgt attaagaaat
    27301 ctatttttct acctatagag tcgtctttaa atatagtatt tttaagttgc cctatatgac
    27361 ttttaaatct aactatttct tctgttatac tgcttttatc tgcatatatt gcaacttctt
    27421 gtgctaatct attctcatct attatacttg ggtcatccag taattcactt attctcaaat
    27481 tcaatttttc tctataatct tctacaacac tacttgaata tttttcaatc tcttctatat
    27541 gattttttaa taaatcacat ctcatggcaa tatcttcagc taatttttta ccttcttcac
    27601 ttctcatttc tcttaatttg attaatgcat cttcaactgc ttgattcaac attgaccaca
    27661 ataaatcttc atcttcttcc ttttcttcta ttttcacaat atcaggaaac tttgcaacat
    27721 tcataacgct aatatcatct ataatatcaa atttattttt tatttctttt agtatgtcta
    27781 tatactgaga tgctaatccc tcatcaaaat ttaagtttac atcttctttg cctaataagt
    27841 caaactttat gtataaatct actcttcctc tttttacata attttttact aaatttctaa
    27901 ctttatcctc taaaaatgaa atttttcttg gaagacgtat gtttatatct gaatacttat
    27961 gatttatcgt tttacactct actaaaaagt aataattatc atccttgtat tctcctcttc
    28021 caaaaccagt catacttata gccattaatt aaacctccaa aataccttca catattttta
    28081 ctgctggacc tgtcatataa gagaaatctc ctacatctat tttaactgtt ccaccttgag
    28141 acgttacatt tacactactt tctaccatat taagtaaatt gcacactatt gctgatgcag
    28201 tcataccagt accacaacct aaagtatatc cacaacctct ttcccaagta taaacatgta
    28261 tattatactt atcttctacc tttacaaaat ttacattcgt tttttcagga aatattttat
    28321 tattttcaat ctcttttcca tatttacaaa catcatctac atctaattca tctactataa
    28381 ctactgtatg aggaaccccc atcaacatag aagtaacttt aagctcccta tctaaaacct
    28441 ttatactttc ttgcacaaaa cgttctttat ttgtaagtac aggaacgtcc ttagctataa
    28501 aacttccttt tcccatattg actcttatag agtttatttc tctattagta agatttactt
    28561 ttatatcttt tataccatct aatgtatcta ctgtaaaact ttctttttta actatacaat
    28621 tatcataaac aaatttacaa aaacatctaa ggccatttcc acacatagct gctcttgaac
    28681 catcagaatt ataatatacc atttctacat ctgcaacttt tgaatctttc acaactaaca
    28741 atccatccgc tcctacagaa aatcttctat ggcatacttt ttttgctaaa gcagtataat
    28801 cagatggatt tatctggtcg aatcttccat ctattgctat aaaatcattt cctattccat
    28861 gtagtttcca aaatttcata agtatcgctc cttcgtaaat taacgcttaa actattataa
    28921 cataaaaaaa ttcccataaa cttataattt atgggaaaag ttttgtaatg acaactataa
    28981 tttgaggatg tgagggagag ttgccattac aattagggta attatattat gtttttaagc
    29041 tagttctttc tatgtttata tattaatatt tctatatgaa ttttatgtat gttttattta
    29101 aactgtctat gaatttttta attaaacatc tggtaactag ctataatcct tctagtagat
    29161 atctattaac atacacctat taattcttta agtgttttta aaacatagtc taaatcttcc
    29221 ttagtaatat ctacatgagt tacaaatcta tattcaccat tttccatttt attaattttt
    29281 atatttcttt caaaaaattc ttttattaaa acatcctctt ttataatatc ttcactcatc
    29341 ttaaaaaata ccatacttat atctggatta acattgttta cttcaatgcc atcaatttta
    29401 tttaattcac aagctaaata ttttgcattt tcatggtctt cattcaatct taaagtcatt
    29461 ttttcaatgg caattatacc agctgctgca actataccta cttgtctcat tcccccaccc
    29521 ataacttttt gctttcttct agcttttgct ataaattctt tatttccagc aagtatagaa
    29581 cccattggtg cagctaaacc ttttgacaca cagaacataa cactatcaca acactttgct
    29641 atttctttag cttctacacc caaagttaat gctgcgttaa ataatcttgc tccatctaaa
    29701 tgtactggta agttatgttt ctcagctatt tttttaattt ctcttaaatt atcaagactc
    29761 acaactgttc cacctgaata tgcattttct acacatataa gccctgtctg tggttcatgt
    29821 atgtcatctc ttctaattgc cttttcaaca agttcaggat ttagagctcc actttcgtct
    29881 tcatctatag ttctaagctg aactccagct attacagcag gtgccccaac ctcatgagtc
    29941 acaatgtgat aacctttacc aataattatt tcttgccctc ttaggcaatg agtaaataga
    30001 gctaattgat tcccaaaagt tccacttgga aggaaaatag catcttcttt tccaacttta
    30061 gctgctgcta attcttcaag tttatttaca gtagggtcat ctctaaagat tgaatctcca
    30121 acaggagcct ttgccatagc ttctctcatt tcgtcagtag gcatagtaac agtatcactt
    30181 cttaaatcga taaatctcat tttttcaacc ttctttcata tttatatact atagaacctt
    30241 aaaattgatt ttttctgtaa agttcatata ctttcatagc ttatactcta cacaataatt
    30301 atactatatt tactttatat ttaatctact ttaaattatt aattttaaaa ataaagtttc
    30361 ctctctaata aatataaata attatacaat ttaaatatta atctctattg tttaaattcc
    30421 ccctagtcac aaagcgtata ttatgtgtat aattaattta ctgactcatt ttggtcaaag
    30481 aaaggggtgc tataaatggc attagatgga ttagttatac attcaatagt cgatgaatta
    30541 tcatcaaaac ttacaggtgg aaaaatagat aagatacatc aacctgaaga tgatgaggta
    30601 atttttaata taagaaataa taaagaaaat tttagattgg ttttaagtgc aagtgcctca
    30661 aatcctagag tttatcttac aagtaattat caaaaagaaa accctctaaa agcgcctatg
    30721 ttttgtatgt tacttagaaa atacatacaa ggtggaaata tagtagaaat ttctcaaata
    30781 ggttttgaaa gaataataaa aataagtgtt gaatctttag atgaattaaa agaaaagaca
    30841 gttaaaaata ttatgattga aattatggga agacatagca acataataat aactcatggt
    30901 gaagaaaata aaattataga ttctataaaa agagtccctt ttagcataag tagagttcgt
    30961 caagttttac ctggtcatga ttattcattg ccaccagaac aaaacaaact caaccctctt
    31021 gatgatatat ctaaggattt gtttattaaa aacctagagg aattggaagg acctatcttt
    31081 aagtctatat attctaaatt tctaggtata agccctatta tagctaaaga aatttgctac
    31141 agagcaggtg taaatcaaaa tgctatcata aaggatatat ctgatgaaca atttgatgct
    31201 ttacacaaag tattttgtaa tttattcaat gatataaatt ctaacaaata ctctccttgc
    31261 attattatag ataaaaaggt ggataaggta gttgatttca gttgtataaa ccttacatta
    31321 tttagcgatt tatcatatat aaataaggat agtatgtctc gtattctgga agatttctat
    31381 agaactaagg atattaaaga tagaattaat caacgttcat ctgatttaaa gaagagtata
    31441 tctgttaagc ttgatagact ttataataaa cttaaaaaac aagaagaaga attatcagaa
    31501 tccgaaaatg cagacattta taagataaaa ggagaattga ttacttcata tatttatatg
    31561 gtagaaaaag gtatggaaag tattgaagtt gctaacttct atgatgaaaa ttgtaatgat
    31621 gtaacaatag aattaaataa aaacttgaca ccatctgaaa atgctcaaaa atactttaaa
    31681 aagtataaca aaatgaaaca tgctaaagtc gagatatctc atcaaatttc cttaaataag
    31741 gaagaaatag attacttaga aaacataatt ttaagtattg aaaactgtga aaatttagct
    31801 gaattacaag atataaaaga agaacttgct aaagttggat acatcaagac tcaaaagaaa
    31861 aacagtaaaa aggatactat cccatctaca aaacctcatg aatttgtgtc ttctgatgga
    31921 tttaaaatat tggttggtaa aaacaataag caaaatgact atcttacact aagacttgct
    31981 gataatgatg acttatggat gcatacaaaa aatattcctg gttctcatgt aataataaag
    32041 tgtgctggta aggaagtccc tgataatact gtatttgaag gagctatgct agcagcattc
    32101 tttagtaagt caaaactttc ttctcaggtg cctgtagact atactaagag aaaaaatgtg
    32161 aaaaaaccta gtggttctaa accaggtatg gttatttatg aaactaacag tactatttat
    32221 gttactcctg aagaagaaac agtagccaag cttaaggtta aatctgaata aattctgcac
    32281 taaatacaaa ataaatgtta gacaactaca cattatcatt ctaaataaaa atagtggcct
    32341 tcttataaag tacaataata aggccacttt ctaattagct tacttttaat tttctaacaa
    32401 aatacttttc tgttttaata actatactta tattcccaac aaatattttc agtcttctta
    32461 tatagatgta attaaaaagt taacactaaa agctattttt taatttattg atttgtttta
    32521 gtaattcatt atattctgat tcatacaatt ctttttttag attatctttt tctatagata
    32581 acatagatat aacagttgta agtctatttt ctaatactag aagattttct tttttgattt
    32641 ggttttctct actaggagtt tttttatttc tgctaattgt atattcgtca taattacaat
    32701 caaactccct tattttagca tcttttatct ctataatata gttacaaata tgtgatacaa
    32761 atactctatc atgagacact ataagcatag ttttatcagt atttatcagt gccttttcca
    32821 gtgcttccat agattttata tctaagtaat ttgttggttc atcaaatact aaaaaattat
    32881 tatcttccaa tattatttta catagtgcta tttttacctt ttctccacca ctaagtactt
    32941 ttactttttt gtagacatca tcacctttaa acccaaatag gcttaagttt atccttataa
    33001 aagattcatc aaatgaacta ttaactttag tattgtatag aacactcttt tcctcatcta
    33061 ataaactttg attttggtca aaataaccta cttttacctt gttatttatt tttatattgt
    33121 catttttatc agccaatatt tcttttatca gagtactttt tccacaccca ttatcaccta
    33181 acaatgctat ctttttacct ctttttatct taaaggaaac attatctaac aggagcttat
    33241 tttctaactt tagagtcata tcttttacct ctactagatt tttgctaatt atctccatac
    33301 catcttgcat cttaatgttc atttctttag aaactttagg tttattcttt acctcaagtt
    33361 tatcaattct gctttttata gccttcacat ttgagtccaa ctttttctta ttagtctgac
    33421 cacccatttt gtgcaaccta gcttctgaat tacccattct ttttggtgtt tttcttatgc
    33481 catcacttaa agctttttta tataaaagag ctttttcaag cctttttttc tctttaacat
    33541 attcttgata ctcaaaatca gctcttttta cttcttcatc tttttgcatt aaataatcag
    33601 tgtaattgcc tttgtaagct tttagttttc catcttctag ttctaatata gttgtacata
    33661 actcatccag aaaacgtcta tcatgagata ttaataataa tgctccctca tgccttttaa
    33721 acatatcttc caaaacccca atgctttttt tatctaagtt tgaagttggc tcatcagcta
    33781 ttatgatatt tttcttatta ctcagcgcat ctgctatttt taacttaacc ttttcccctc
    33841 ctgataagtg ttcttcaaat ttatctggag catttaaaag actcttctcc ttactatgac
    33901 tacatgtttc aatattattt tcactctgac ttatataaga atagctttct gtaaggtaag
    33961 tatatccttc atcaatttct atttctccca atattgcttt taataatgtt gtttttcctt
    34021 gaccatttga accaactaga cctattttgt cattttctaa tatttcaagt ttatctatat
    34081 ccaaaattaa tttatctgca taatatttct ttaaattctc tacttttact aacaacataa
    34141 aaaatccctc cttaacacac ttaaatataa ggagagattc tataaatagg cataacaaat
    34201 aaacgtatag actataatct actctcctta atttaagcat tgcaaataaa gccaccaaaa
    34261 taggcttttc aaaaattaca atactttaaa ttataaaaaa tagattatat tctcattgtc
    34321 ctagttacct tgccctttct ttcatttatt tttaatcatt atatcaacat taattacaaa
    34381 tgtctataga aaattaacta attttagtta ttcaatatac aacttattct ttaaatttat
    34441 tcttcttcaa ctttaaagtc ctgattattt aaaattctgt ttaatacaat tccaacaatt
    34501 gcagctaaac taagaccagt tatctttact gtacttgtta tagggattcc aacagaaata
    34561 cctttattag ataaatatgt tgttccaaga cctattaata atataactgc tatgattaat
    34621 atatttattt tactttctac acaagaactg tcccttatag tttttaatcc tacataagtt
    34681 atcatcgaaa atagcattat actaattcca cccataactg aacctggtat actttgaaga
    34741 aatccaccaa acttgcctac acatgcaagc aatatagcaa atattgctgt acgtctaagt
    34801 attgaagggt catagttttt agttatagca agtactgctg tattttctcc ataagttgta
    34861 ttggctggtc ctcctaaaca ccctgcaact atagtcgcaa atccatcccc aagtaatgtt
    34921 ctatttaatc cgggattttc tataaagttt ttacctacta cagcaccatt agtagtcata
    34981 tctcctatat gttccataaa tacagctaat acaactggag atataatcac tattgctcct
    35041 aaactgaact taggaactgt aaagttaggt attgcaaata aacttgcttc tgtaatagta
    35101 gttatatcta ctaatcttaa tatcaaacag attatatacc cagaaaaaac tgctattaat
    35161 attcctaatt gttttataaa tcctctacca aacttattgg ttaaaattgc tattgctaaa
    35221 gttataaatg ctatcacaaa attggctgaa gccatactaa aagctgttgg caataaattt
    35281 aatcctataa ctactatcat agctcctgta acttgtgcag gaaaatataa tttaatttta
    35341 tttacaccaa ctacttttac tataatcgac attataatat aaattaatcc tgctactatt
    35401 ataccacctt gagcatatgc taaatctcca ccatatgcct ctttagctgc tagtataact
    35461 ggtataaacg caaaacttga acctaaaaag gcaggtactt ttccttctgt acaaaaatga
    35521 aatatcaatg taccaacacc agcacagaaa attgcaactg acggattaaa acctgtcaaa
    35581 atgggaacta atactgtcgc tccaaacatg gctaatagat gttgtaaaga cattatcgtt
    35641 tttttcataa aaacctccaa aattattata tataaataaa tcctctgttt aattaatatc
    35701 ttttaattaa ttatcattcc ctagattcta ttttttaacc tctatatact tattatataa
    35761 tttatcatta ttttacattt tacgacatca aaaactcaaa taaaggagaa taaaaactac
    35821 attaagactc acatccataa aattataata tttattttgt gcaatctatg taagctttat
    35881 cctcctccct gactattcaa tgctaagctt ttatataata cttaaaaata attattcttt
    35941 gattgtaact gaatcttctc catcaatttc taataaactg acagatataa tttcatgtct
    36001 agaagtaggt acattttttc ctacataatc tgctcttata ggcaactctc tatgccctct
    36061 gtccactagc actgctaatt gtattgattt aggtcttcct atatctataa tagcatctag
    36121 tgaagctctc acagttcttc cagtgtataa aacatcatca actaaaacta ctgtcttatc
    36181 atttacatta aaatctaaat aagttccttt aactacaggt tcaacatgaa ttttttccaa
    36241 atcatctcta tacaaagtta tatcaatatc tcctgtatct acttttgttc cttctatttg
    36301 ttctattttc ttagaaattc tatttgcaat tggcacacct ctagtcttta ttccaactaa
    36361 aactagattt tctacacctt tatttctttc aattatttca tgacttattc tagtaattgc
    36421 tcttgctatt gccttttcat ccattaattg agctttttct accatatcat aattattgtc
    36481 aaagatataa tatatctatt tgacaaatct actcctttct tttaattttt tataaattta
    36541 tttttattta aaatttcaat ttaaacaaca aaaaaacttc tcatcacaag acaagaagct
    36601 cttatataaa aaatatacag tgcaatttag caattgtctt acgatatctc tgtatcgttt
    36661 aaagataatt ttttaatcta tcaaatcaaa ttatatattt atatttcaaa tttttcaagc
    36721 ttttttaaac aaaatacttt aatataagat attttattta aatttcacta aatttattta
    36781 cttatataaa aacaaaaaat gatttataag tattatacaa atagttattt tatcttttta
    36841 ataacttcct taaaatactc aggtaattct gaattaaatt cgatatattc cttagtagta
    36901 ggatgtataa atcccaactt cttagcatgc aaagtttgtc cttttaattt aaatttagtt
    36961 tcttttggac catatacata atcacctaaa agtgggtgat ttatagacaa agcatgaact
    37021 cttatttgat gagttctacc agtttcaagc ctagctctca tatgtgtaaa cttatcaaat
    37081 ctttctacaa cttcaaagtg agtgattgca ttttttccat cttttactac agccattttt
    37141 aatctatcct taggatttct ccctataggt ttatcaacag ttattttatc ttctttaacc
    37201 acaccatagc atataaattc atactcccta gttatagtat gttcctttaa ctgttctgct
    37261 agaaaattat gtgcataatt gttcttagct atcataagaa gaccagaagt atctttgtct
    37321 attctatgaa ctataccagg tctaataacg ccatttattg atgacaactt atctttacaa
    37381 tgatataaaa tcccgtttac taacgtattt tcatagtttc caggagcagg atggacaacc
    37441 atatcctgag gtttatttat tattaagaca tcatcatctt catatacaat atctattgga
    37501 atatcttgag gtaaaacttc taatacttta ggttctggta tctctataac aatattatct
    37561 tcctctttaa ccagatatct agctttttct actttattat taacctttac ttttccatct
    37621 tttataattt tttgtatata acttcttgac atatcaccta attgttctgc tagataaata
    37681 tcaagtctaa cttcttcttc ctcttcaagt actaaaaact cttttacttc atccattata
    37741 tcacctactt ttactttcaa aaaataaaac atatatacat aaaaacacag ttcctacaac
    37801 tacaaataca tcagctatat tgaatacata ttcccatata attctaaagt cgaagtaatc
    37861 tactacaaaa cctaatcgta ctctatcaat tagatttccc aatgcaccag atataattaa
    37921 tataattccc aaccttccaa atatatgtac tttccttgta ttaagatagt atagtccaaa
    37981 tactgttgca agtaatgcaa caattataaa tatccattga ttattttgta ataatccaaa
    38041 tgctgcacct ctattttcga cataagttaa atgaaataca ttatttatta ttggtattgt
    38101 tgatacatcc accaaattat tcaataccca tattttagac agttggtcta aacctatgag
    38161 tagaattatt attaatatat atagcaatga tttttccccc tataaattat ttaaaaacca
    38221 attttatttg aagcacacta ttattattat acaaaaaaaa tgctctaaag agcaacttta
    38281 ttaaaattgt attttcttaa taaagctaga acaaaattta aaatagtact acttttttta
    38341 tattgtagat ttctacatat ttaaaatcat atcattatgt ataaaaaatt taaaaatacc
    38401 atactaatca atattttttg tgtattttat agattaaaga ttaatgatgt ctgtaattta
    38461 aacttacaat caccactaat cttcaaacaa atatttttac ttttgcactt gcttattttt
    38521 atctaaatgt tgtataagtt cagatactgt tacgaattta tatcctctct cttttaattt
    38581 aggaattact acttctaaag cttgtatagt ttgtgattta tcatttcttt tagtgttata
    38641 atcatgtaaa agtattatat taccattttg gacctttgta aggatagtat ttataattgc
    38701 atctactcca gggttagacc aatctctagg gtctaagttt gaccaaagaa ttatattcat
    38761 gcctttagaa actataatat cacagacact tttactcatg gctctatatg gaggtctaaa
    38821 tatctttggt tctactccta ttacactttt tataatattt tgcgtatctg ttatttcttt
    38881 ttcaacacta ctataactat tttttgcaac atttatatgt gtaaatgtat gattccctat
    38941 ttcatgcccc tcatcatatt gtctttttaa taattctttg ttatattcta ctttttctcc
    39001 aactacaaaa aaagttgctt ttacatcatt tttctttaat atatcaagta cttgtggtgt
    39061 aaaatcctca tctggaccat catcaaaagt taatgctaaa attttttcat cctcatttcc
    39121 tttttttatt attacatctt cataatcgtc ttttatattg tcatttaaac tatatgcttc
    39181 ttttgaacta tcttgattat gtgtattatg attatatgta tatacaccta ctatagataa
    39241 taaacatata catatacccc atattatttt cttcatgtca ttacctcttt tctaattcat
    39301 tctagcaata tattttataa tgtcagtttt ttaatctctc aatattccat ttttatttaa
    39361 atcagttaaa tttgttaggt cttctgaata aaagttagaa tcttctacat cagggttttg
    39421 cattgcatca cctaataaat tattttcttt ctttgcacaa tcattacata aacttgtatc
    39481 tggcaatata tccaatcttt ctaaatctat ttgattatga cataaatcac aaatcccata
    39541 tgttccattc tctattttag ataatgctaa gtctatttga tacaatcttc cctcttcatg
    39601 atttattaga ctgttttgca tattttgcat atataaatct gttcccatgt ctcctatatg
    39661 attatcataa ctagataatt ctcctgatga atacttttca cttgtatgtt tagttgtatc
    39721 tccaaataaa gtattatctt tcatatcctc tactaaatta gttaaatttt ctctttcttt
    39781 caataattta tctttatatt ttttagtatc catttttaac acctctaatt ttaatattta
    39841 catcataaaa atagtatgtg gaaaagtaaa ttaaacatac aataaaaata agatttgatt
    39901 cgaaaaatgg aatgtctcaa aatgaaattt ttagttcatt taaccctctt ttttatatga
    39961 aatcaaatat atttttatcc tttcagcaat aaaaaagaga cttatctcta ttttgagata
    40021 gtctcttctt tgaacataat ttaaatacaa ttttttaatt tttatagtta ttattttact
    40081 aacttgccaa tttatgatta ttttgttctt taatatgttt tgctttttta aagaataaaa
    40141 gaccaagaat tattgctaca ataacaccta ttccattaga tatattaact ggtagtctaa
    40201 atccttcttt tgcttgcatt atataactaa atgttactac agtcataaaa agtgctggta
    40261 atgtagttat ataatggttt ttatttgctt tgactaaata tgcagaacca gtccacaaca
    40321 ttatcattgc aagtgtttga tttgcccaag agaaatatct ccaaattata ttaaaatcta
    40381 taaatgtaag agcaacacca actgcgaata atggtaaagc tattaaaaat ctatttttga
    40441 ctgcatcttg attataattc attgcatctg ctattgtcag cctagcactt ctaaatgctg
    40501 tatctccaga agttatagga catgccacaa ctccaagtat agctaaagct cctccaatag
    40561 gccccattaa tccaacagat actgtattta ctactgttgc tgctccacca tcattaaata
    40621 tcacattaag ttgaggtatg ccatggaaat atgacatggc tgctgctgcc caaactaaag
    40681 ctattatacc ttctgcaacc attgacccat aaaatactgg tcttgcctca ctctctttct
    40741 caacacatct cgccataagt ggtgattgag ttgcatgaaa acctgatatt gctccacatg
    40801 ctattgttat aaataagtat gggaataaag gtgttccatt tggattcata ttttgtaaat
    40861 ttatatttgg tatgttatac ccctttatta ttaatcctcc agctacacct actgccataa
    40921 ttaataatgc tgctccaaat aaaggatata ttttaccaat caatttatct attggtaaaa
    40981 cagtagccat aatataataa agtattatca ctccaaccca tatttgtgcg tttacacctg
    41041 tcaatgtctt taataatcct gctggacctg ttacaaatac aactccaacc aatactaaaa
    41101 gaataacact aaatattctc attgctattt ttgcaccatt tcctagataa aggcctacca
    41161 actctgatgc agatgtacct ttgtttttca ttgatagata tcctgaagca aaatcgtgta
    41221 ctccaccagc aaagattgtt ccaaacacaa tccataaaaa tgctgatggt ccaaataatg
    41281 ctccttgtat agctccaaat atcggaccta accctgctat atttagaaac tgaattaaaa
    41341 agattctctt ccatttcatt ggcacataat ctactccatc cctacaagct atagctggag
    41401 tttgattttt gtcattggtt ccaaaaacct tttctacaaa agtaccatag acaaaataac
    41461 ctactataag tactactatt gaacctaaaa agcttaccat aaattcatcc ccttagtttt
    41521 tatataattg ctttataaat ttttatgagt ttaagaaaac tatttccagt tcaaatagta
    41581 atactttttt atgctaatat aaatattaat tacattaagt gcatatttaa gtacatgaaa
    41641 tgactttata tatgcattaa cagcctaaat tcttttactt tgcttctact tacagttact
    41701 tcataatcac tattttttaa ttttaatatg tatgtattat taaaccatgg tataatttct
    41761 tttactttgg ttaagtttac gatataagac ctatgtgttc taaaaaatgt tttatcattt
    41821 ataagatttt cgacttctga tatgccttct tttaatataa acttttcttt ctcagtatat
    41881 ataaatgtct gcctttcatt agcttcacag taatatatat catcaatatc tattacaact
    41941 aatttatcac ctttccaaag gctaatttta tgtgttattt cttctatctc ctgatttact
    42001 gcttccttct tatatttgta taaattacta tttacattaa atagttcaat atcactcatc
    42061 tcactttttt ctaatttatt cagcatagaa ataattctct cttcagaata tggtttcaat
    42121 atataatcaa atacatccaa agaaaaagca tctactgcat aactttcata tgctgttata
    42181 aaaacaattt taggtcttga tttaaactga tttaatgttt ttgcaagtag cattccatca
    42241 agatgaggta tatttatatc taaaaaaatt acatctattt tattttcctg aataaagtct
    42301 aacacctcta taccattggt aaattcactt actacctcga ttccactttt attttcaata
    42361 aaatatctca attcctttct tgctggaaat tcatcttcca ctattatagc tctcatactt
    42421 ctactccttt acataaaata ctatcaaagt cccattatct attcttctta tattaagccc
    42481 tcttccatac atcagtttaa gccttaaatg tacattataa agcccaatct tattttctgg
    42541 catattatct tgatatacat tatttataat ttcctcactt atacctatac cattatcctc
    42601 tattgatatt ctcacagtat tttctaatga atacggtaac ttttttatgg atattttcac
    42661 tacaccagct ctaccacttt ctaaaatacc atgtattatt gcattttcca ctaatggttg
    42721 tataatcaaa cttggaatct ttatatttac atcttctata tcataagata cagttagtaa
    42781 ttctccaaac ctagcttttt ctatctctac aaaagattta acttgttcaa tctctttatt
    42841 tatatcaatt aagttatcac tatattcaag attatatctt agataagttg ataaatttat
    42901 tattaactct ctagccttat ctggactaaa tcttataaat gaagctattg tgtttaggga
    42961 attaaacaaa aaatgtggat taatttgtct ttgaagtgct tttatttctg ctttatttct
    43021 cgcttctata tcttttttat ctttctcaat cccctctact atagatataa caaatcctat
    43081 tccaatctgc ccaactatta aaggtaaata tattccaccg attatttgaa ttgctaaaga
    43141 atgtggatat gatattaagt atataagtaa tatagtaaaa ctttcagaaa tcatgcctac
    43201 caatattcca tacattactc tatgttgttt tggtatcctc ttatatagaa atcctgataa
    43261 tacacctgct agtatacttg ataaaagaca tggaacagat gttatccccc caatatccat
    43321 aaaatatcta tgaatccctg aaaaaactcc tgctgtaata cctaccatcg gaccaaataa
    43381 aatgccacct gatactatag atattattct agtgtttact attgacccca tataatttat
    43441 accactataa gttccaaata tggctaaaaa agtaaaaact aatgctatac agaccaagtc
    43501 attaaaacta tattcttcct tttgaaatat ctgcttaaat atttttaact ttgttattag
    43561 aagaaacaat actacaataa ggcttgtctt ttctattaat gcgattaaaa ttgatgtttt
    43621 cataatctcc ctttaaaaaa taaattttta cacactctaa atttattatg gttgttataa
    43681 attacatatt tgaagtaatc ctatcacaaa actttccaca tttaatcttt taattaaata
    43741 agaaatagtt gtacttctat taacaactaa tactagctag cataagcttg taataacttg
    43801 tagttattat taactttaca attctagtat ttaattttat actttagaaa tctcttttct
    43861 tagaaataat actttcgaat atcatataat acaatattat gtagattctt actcatacaa
    43921 catatttctt taaaaatttt atactattct ttgttcaaat atctcatttg atttaattgt
    43981 gttaaacaca cattatcatc tctctgttat atatttatta tatagccgta tatcgataaa
    44041 gtaaataaat cccatattta aaataatatg tttgacaata aattattata atgtatattt
    44101 accataataa tttgtcaacc ttgaaagt
//
LOCUS       DAEPKC010000021        43858 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.021, whole genome shotgun sequence.
ACCESSION   DAEPKC010000021 DAEPKC010000000
VERSION     DAEPKC010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 43858)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43858)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43858
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.021"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(130..1380)
                     /gene="cme"
                     /locus_tag="KR294_001262"
     CDS             complement(130..1380)
                     /gene="cme"
                     /locus_tag="KR294_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter Cme"
                     /protein_id="HBH0239346.1"
                     /translation="MENKNTNSTWKKKVILFLASQYISLFGSSLVQMAMIWYVTLQTS
                     SGVWVTVLTVCSFIPQMIISFFAGVWADYYNRKVLIIVSDSTIAISTLVLILFMMSSN
                     GTTSELIAISVISVIRSLGSGVQTPAVNAMIPQLVPEEHLMRFNGINSSLQSIVQFIV
                     PIVAAAILGFGNKINQVLLIDVFTAIIAIVLLIFIKIPKHDIPKQTEKVSFFADMVSG
                     IKYCFSDKFIRKVLFTYGAFMLLCVPSGFLIGLLIERTFGKGYIYLSIIEMIGFLGMV
                     LGGLIIGVFGGFKNRNKTFFLAILSYAIFSIILGLVTQAWQFFIFMFFTNFSIPIIQA
                     SAMTMLQEHVAPQMLGRVLSLPIIIYTGFIPLGMMIFGPMADVISINNLIIIAGIILL
                     FFALAIPYSKQFYKQGISKSNESE"
     gene            complement(1466..2212)
                     /locus_tag="KR294_001263"
     CDS             complement(1466..2212)
                     /locus_tag="KR294_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH0239347.1"
                     /translation="MDTYTTSEVADLIGVHPNTVRLYEELNLIPKPKRNTNGYRIFND
                     FHIEQFRFARTALKIEVVQRGLRKDALEIVRTSANRDFDKAISLVNQYLQQLEIEKSN
                     AEEALTIVAQILNGNTPETNKLFLTRKETAEHLNVTIDTLRNWEMNGLLKVKRKQNGY
                     RVYTDEDIKRLKIISALRCANYSLSAILRMLNALSSSPNTNIKTVLDTPKDDDEIISV
                     CDKLITSLKEAEHNAKTMKSHLQIMKKQFS"
     gene            complement(2365..3387)
                     /locus_tag="KR294_001264"
     CDS             complement(2365..3387)
                     /locus_tag="KR294_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HBH0239348.1"
                     /translation="MNKNNCLDLIFEKVDPSSVGMSSEKLSQLEPLIISQYSNINGII
                     IARKGKIVFEKYYNGYNADDTFHVASVTKSIISALIGIAIDKGYIKDVDQKVVDFFPE
                     YTCSPSEICKKAVTIRHLLTMTAPYPFKNMTESLERLCKQKDWIKYTLNQLGQKGEIG
                     TFKYSSAGTHLLSAIITKTTGKSAREFANEYLFKPIGMKVIPDYDMKDFGFEDFFGKN
                     LKGWAKDRQGYSIGGWGLTLSARDMLRFGFLYLNDGIWNNKRIISKSWIEESVKMNSN
                     EYGYLWWLCKKDGVLWYSAMGTGGNAICCIPQYDLVIAIPSKIVFKPRDRWEFIEKYI
                     LTSIID"
     gene            complement(3387..5807)
                     /locus_tag="KR294_001265"
     CDS             complement(3387..5807)
                     /locus_tag="KR294_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HBH0239349.1"
                     /translation="MKEIKINGAKIHNLKNIDVSIPKDKLVVATGVSGSGKSSLMFDI
                     VFEEGRKQYLQSLGILAGIDSEDKFDNIQGLAPTIAVQQNIIRQSNPRSTVGTRTNIL
                     NMLTLLYSVEGQIMCTMCDTPVSDNLICNNCGYEEERLRPSYFSYNSSDGMCMKCSGH
                     GAYFEINIEKLVLDKHDTLKQVLDRAKITPGYLRVFSKKFNDYLDIQFLQLPEEIRNE
                     VLYGHYENGKKSSSLSKVFHNRYKRGEDLNGVYTMTACSDCNGFKIGEEARRVLLNGK
                     HIGELGKMTILEIDDFLKLLINQGNLNTFGTNLVNDILSKTQHLIESRLGHLSLYREM
                     STLSGGEMQRLFLNSHLDSEMDSLIYVLDEPTAGLHESEKIDILKSLKKLKDLGNTVI
                     VVEHDKNTIEMAEHIIDIGPKAGVEGGQLVYQGDLEGLLQSDKSLTGQYLSGKYPMPN
                     RTSNKNITHTDKIPCITIQNANTNNLKNVTVSLPLGAMVGISGKSGSGKSSLISDTLL
                     PLLRSQFNNHTINNQINSSESEIGEEDDYAVVETIADRLIGTKHISGYSEISQSPIGK
                     NMNSTPASYIGIWDKIRTLFAGQPESLEQGFTAGHFSFNSKGACPKCSGSGYEKVWLG
                     NNLSIDHICSECQGKRFNDESLSIKYKNKNIHDILNMSVSESVHFFKDIPNIVSHLNV
                     LEQIGMGYIKLGQPTPTLSGGESQRIKLAKEIGKKRNGNILYVLDEPTTGLSLYDTSK
                     LIQLLDELVENGNSVIVVEHDIDVLNVCDWIVELGPEGGDKGGYIIAEGSPKTLKENP
                     KSITGRYL"
     gene            complement(5893..6813)
                     /locus_tag="KR294_001266"
     CDS             complement(5893..6813)
                     /locus_tag="KR294_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBH0239350.1"
                     /translation="MTNAKSKKEYLNRICKVQDYIEEHLHEPLSLDELSNIAGFSKFH
                     FHRIFKAIEKETLAQYVNRLKLENATAFLIHRTDMTVTDIAHYFGFTDSAVFSRAFKN
                     YYKISPIKYRNNYSKNCKEPYKISQYNRSISKPKCKNTREVKGEIEILELDNMNTIYT
                     RYTGSYGNLTSTFPKLLERLFTYASEQNLLGLENTQILAIYHDNPQFTQEHQLRTSIC
                     MTIPDNIVVKENDNLGNMIIPSGKYLVGHFDISKSEYSDAWDFMYNEWLSNGNYKLRA
                     SFPFEVYLNNPHNHPQNRHLVDIYLPIEPF"
     gene            7403..8329
                     /locus_tag="KR294_001267"
     CDS             7403..8329
                     /locus_tag="KR294_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conserved phage C-terminal domain-containing
                     protein"
                     /protein_id="HBH0239351.1"
                     /translation="MSNSFYQLNSAVLYFNEKRDVNRIRFNHYVMRKENIQRLKGTLP
                     RGQFMMTVRKAASDLDVSISTISRLVNEFIDLGILRLISRGVKGNCCSVYSYVCSESS
                     NAEIVTKNGDIFKNIEKYIDATINNNQKTMKYKHRNELFKNSNTNIYSRINQESIDKD
                     YDLIIHTGYETENETKKKELLKNNLNKKNLNKNTFENSDEDLTEDSTYKNPESIHEII
                     IRKLNSESGKNFKADLSITKALIDKRLKEGYSLEDFYKVIEAKVRRWRYTDMEIYIEP
                     TILFGYEFESYLNEESSLSACNYGDMCYEDMY"
     gene            complement(8712..10364)
                     /locus_tag="KR294_001268"
     CDS             complement(8712..10364)
                     /locus_tag="KR294_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp21"
                     /protein_id="HBH0239352.1"
                     /translation="MNKKNLAILISGMMFFSSSSAIFADNTTKQERLIGKTRYETAVE
                     VSKLGWVQSKTAIIVNGNSIQSALCANPFAKLKNAPILLVNNNSIENSTKAELKRLGV
                     DNVYIVDSGNSISSKVENEIKSLNIKINKIVGNNIYEMSTNVLKEIDKIKKIENVAVV
                     NGLKGLSDAVSIASPAAIHNMPIILVSDENSNDSSINFLNNRSIKKSYIVGGNKILSD
                     NTVKKYPNRERISGSDRNNTNAKIIDKFYKDKKINNVFVAKDGINQENALVDSLSIGV
                     LAAKENSPIMISNGSLVNSQKEFIKNKDIDEITQVGGGYNQKAFEDILKLKNVNIRNK
                     TKKISLIQAKEILKQALPGSNILVCYYDEDDNEYDCKVIKDNILYEIEIDAYSGKIIE
                     IEKDDDLNDNNLGTQNISLDKAKSIALDAIPNGNLIYCKYDAEDNEYEAKVIKNKKTY
                     ELEISAFDGRIVDIDMDNDSDDDFDDNDKNNSNTNDNSSIISAEKAKSIMLDKVPGGK
                     IVKFKYDEDDKEYEGEIIKGKTEYEITINAITGKILEFEIDD"
     gene            10963..12084
                     /locus_tag="KR294_001269"
     CDS             10963..12084
                     /locus_tag="KR294_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBH0239353.1"
                     /translation="MEAKKLGFGLMRLPIKDENDVTTIDMEHLNKMVDTFLERGFTYF
                     DTAYVYHMGKSEIALRESLVKRHKRESFTIATKLPLMALKKKEEQETIFNEQLEKCGV
                     DYFDYYLLHNIGVSHYEVAKKFDSFKFIEEKKKEGKIKNIGFSFHDSAELLDKVLSEH
                     PEVDFVQLQINYLDWDNESIQSRKCYEVAEKHNKPVIVMEPVKGGTLAKIPEKAEKLL
                     NDYNPDMSISSWAIRFAASKDNVMMVLSGMSNMEQLLDNTGYMQNFKPFVQEEYNIID
                     EAVEIINESILIPCTACQYCVEGCPKNIAIPNYFALYNAEKQALNTGFSTQMVYYNNY
                     TKTYGKASDCIECKQCEESCPQHIKIIDALKNVAETFEK"
     gene            12120..12533
                     /locus_tag="KR294_001270"
     CDS             12120..12533
                     /locus_tag="KR294_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH0239354.1"
                     /translation="MTISEVSKKYELSADTLRYYERIGLIPPVNRNKSGIRSFTEEDC
                     EWVNFIKCMRGAGLSIETLIEYVAMFQQGSSTIKARKELLIEQRNQLAKRIEEMQKTL
                     ERLNFKIDRYEEGIIEKEKVLKSSRNKKMEAVSYE"
     gene            12526..13065
                     /locus_tag="KR294_001271"
     CDS             12526..13065
                     /locus_tag="KR294_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBH0239355.1"
                     /translation="MSKNVLIVSASPRKGGNSDLLCDQFIQGVLESKNQVEKIFLKDK
                     DINYCTGCGACYEKEANCSQTDDMGEILEKMIGADVIVLATPVYFYTMNAQMKTMIDR
                     TCSRYTEICDKDFYFIVTAADENVADMERTIEGFRGFTSCLNGSKEKGIVYGVGAWNV
                     GDIKGSKAMKQAYEMGKLA"
     gene            complement(13265..13750)
                     /locus_tag="KR294_001272"
     CDS             complement(13265..13750)
                     /locus_tag="KR294_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239356.1"
                     /translation="MSKSELTAETTEEMLEVLSGKDYDIACHLHELGKSLDCKIEPKT
                     GARSYKIVYSTKKPKRSLFTIECNEKKWRVKANLFHLNTYKDAVEECSKTIKDSITKT
                     RTCKKCNSKCIGGSSFELDGKSYLTCIGSGHYFANMEEMDWKNLEKLITKENNIMQES
                     V"
     gene            14655..15032
                     /locus_tag="KR294_001273"
     CDS             14655..15032
                     /locus_tag="KR294_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003483933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HBH0239357.1"
                     /translation="MSKVVIATEKAPGAIGPYSQAIQVGNIVSTSGQLPIDMKTGELV
                     SDPKEATKASLDNVKAILEQAGTSMDKIFKTTVFVKDLKDFNDINEVYATYFKENPPA
                     RSCVQVAQLPKDAVLEIEAMAVL"
     gene            15428..17233
                     /locus_tag="KR294_001274"
     CDS             15428..17233
                     /locus_tag="KR294_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH0239358.1"
                     /translation="MLSKLKEFQQEMIKYTETVASVLDVDIEIVDDRLIRISGTGLYK
                     SKINESVVTEGFIYDNVIQTGQELVVLDICDNQLCIECSHYMKCLNKVIIAVPIKYNN
                     RTIGVIGAISTDKTKKVEISAKIDNYLKFVNHICDLISMKIEEHEASKNSSRKMDMMI
                     EIIENVEKGVIILDINSKISYINNIALKKLDIDKNIIENIVNIVSVESSSNGHELLEI
                     DIDNKIYNINAKIIPVYPYINQYDKIIIFDKTYINHKGHGKVNSGWGNSDIESIIGNS
                     EAMLKVKERTKKLAKSNSTVLITGESGTGKELIARAIHAEGSRWNKPFIAINCAAIPE
                     NLLESELFGYIKGAFSGASSGGKVGKFELANEGVIFLDEIGDLSMPLQAKLLRVLQER
                     KFARIGSNKLIDLDIRVIAATNKNLLKLVNEGKFRDDLYYRLNVIPINLPPLRERKDD
                     IEAIMMKFASKYSLELGIQLNKIEENVMNMLINYNWPGNIRELENAVEYMMNLVGDDG
                     IIYKDMLPLDILNYYNINGNIYKNKDVNIIFEDDIVGGIVENQERILSIKELELTYIN
                     KLLNKYGRDTKTKKKIAKDLGIGLATLYRKLEEEQ"
     gene            17310..17847
                     /locus_tag="KR294_001275"
                     /pseudo
     CDS             17310..17847
                     /locus_tag="KR294_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427977.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="2'-5' RNA ligase family protein"
     gene            18461..19675
                     /gene="dpaL"
                     /locus_tag="KR294_001276"
     CDS             18461..19675
                     /gene="dpaL"
                     /locus_tag="KR294_001276"
                     /EC_number="4.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopropionate ammonia-lyase"
                     /protein_id="HBH0239359.1"
                     /translation="MREIKWKLNNLPKSEEKEKGIEFLKDEEIAKAKAFHESFPQYEK
                     TPLVKLDNLAKSLGVSGIYVKDESYRFGLNAFKVLGGSYSMGRYLAQRLNTDISELGY
                     DKLTSKEIKEKLGEITFFTATDGNHGRGVAWTANKLGQKSVVLMPKGSSEFRLNKIKG
                     EGADASITDLNYDDAVRLANDYAEADDHGVMVQDTAWDGYEEIPAWIMQGYGTMAKEA
                     IEQLKEYGVDRPTHVFVQAGVGSLAGAVQGYVASIYDECPITVVVEADEADCYYKSAE
                     AGDGKPRFVGGDMPTIMAGLACGEPNTIGFEVLKNYSSAFVSAPDWVSAKGMRILGNP
                     LRGDEKVISGESGAVTTGALVSILESEDLKDLREALKLDENSKVLLISTEGDTDPDKY
                     RDIVWNGECQSK"
     gene            20008..21195
                     /locus_tag="KR294_001277"
     CDS             20008..21195
                     /locus_tag="KR294_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgeY family selenium metabolism-linked
                     hydrolase"
                     /protein_id="HBH0239360.1"
                     /translation="MLNETRKKQLTEVCQDLIRNASYSGQEENVVKAIEENFALLGFD
                     SWSRDRYGNIVGCIKGNKPGKKILFDGHIDTVPVPDASKWSVPPFEARIVDGKIYGRG
                     TSDMKGQVSAMMAAVSYFAEDTNKDFEGELYVAGVVHEEIFEGVSAREISKAVQPDYV
                     VIGESSELNLKIGQRGRGEIVVETFGKPAHSANPEKGINAVYKMANVIQKIQQLVPPT
                     HPVLGDGILVLTDIKSSPYPGASVVPDYCKATFDRRLLVGETREGVLAPIQALLDEMM
                     KEDPELNAKVSYAVEKADCYTGNTIESERFFPGWLYDEEDEFVQAAYKGLKEAGIDSE
                     ITQYSFCTNGSHYAGEAGIRTIGFGPSKENLAHTIDEYIELDQLFKGAEGYYGILKSV
                     YKK"
     gene            21211..22794
                     /locus_tag="KR294_001278"
     CDS             21211..22794
                     /locus_tag="KR294_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacylase"
                     /protein_id="HBH0239361.1"
                     /translation="MRTLIKHGLIVDGNKTPAYEGDILIENEKILKISQDLNEEADKV
                     IDAKGRVICPGFIDTHSHSDLVILVNPYNEVKIRQGITTEVLGQDGISMAPLPQEHIS
                     SWRKNLAGLDGESDEIDWKYETTENYLKMMDYNGVGLNETYLVPHGNVRMEAMGLEDR
                     PATKEEIQKMCEITERELKAGAIGLSTGLIYIPCAYSLTEEIIEMCKVVAKYDGVFVV
                     HQRSEADTILTSMEEIIEIGKQSGVKVHFSHFKVCGKANWKYIPQVIELLEKAEKEGI
                     RVSFDQYPYAAGSTMLGVVLPPWAHSGGTDKLIERLSDENERAKMKKDIANGIEGWDN
                     FIEFAGIDQIFVTSVKTEKNKDTIGKSLLEIGKMRGKDPLDATFDLLKEEENAVGMVD
                     FYGLEEHIIGFMKRDEQNVCTDGLLAGKPHPRAYGSFPKILGRYVRELNVLTIEEAVY
                     KMTKKAATSFSIKDRGELKEGYFADIVIFDKDTVSGCDDFINSMQYPTGIDYVIINGN
                     CVVEEGKYNKIKAGKVLKN"
     gene            22822..24150
                     /gene="ssnA"
                     /locus_tag="KR294_001279"
     CDS             22822..24150
                     /gene="ssnA"
                     /locus_tag="KR294_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative aminohydrolase SsnA"
                     /protein_id="HBH0239362.1"
                     /translation="MILVGNGRLISQDSLNPYMEDGCVVINDNLIEDIGTTEEMKAKY
                     PVHEFIDAGKKIIMPGLINSHMHIYSSFARGMAVPGKPSENFLEILNNLWWRLDKQLT
                     LEDTKYSAYATYIECIKNGVTTVYDHHASPNAIEGSLFTISDVAKDLGIRTCLCYEVS
                     DRDGGNTIQQGINENVNFIKYAQKDDTDMIKGMFGLHAAFTLSDDTLNKCASEMAGLD
                     TGYHVHVAEGLADLQYNVDKYGKRVLERFNDFGVLKEKTIAVHCIYISAEEISLLNKT
                     NTFVVHNPESNMGNAVGCSPAIELLKRGVTVGLGTDGYTSDMFESLKVANIIHKHHLK
                     DPRVGFEESQTMLFDNNRKIAKAYYKNDLGVLKKGAYADVIVVDYIPHTPLTENTIGG
                     HTIFGMSGRSVDTTIINGKVLMKDRKLINIDEESILAKSRELSQNLWNRI"
     gene            24295..25647
                     /locus_tag="KR294_001280"
     CDS             24295..25647
                     /locus_tag="KR294_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HBH0239363.1"
                     /translation="MSRDKSPKIAPVDERLPVSKSWVFSLQHVLAMCAGAVAVPMMIG
                     SAARLDHASIVFLINACLFMAGIGTLIQSVGIGNIVGAKIPVIEGTSFAAVAGMTAIA
                     SSYSDSQVAIQTVFGSVIVAGLFCILLAPVFEKLIRFFPSVVTGTVVMVIGISLFPVG
                     IKWITDNKLEAVEPNSLALALAVLAITLLSFKFLKGIWNSTAILVGIVLGTLLSMAVG
                     MADFSAVNGVGWLNLNVPLKFGMPRFEPSAILSLCLIMLVLMTESVGNMIAIHEMVDK
                     EVTGKNIKRGLFGDGISTALSGIFNSFPITPFGQNTGIVGLTGIKSRFIAVYAGVILL
                     VLGFLPKFAAIIGAIPKPVLGGVGFAMFGMVMVGGVKTLSKVKFDGTKNGVIVAVSVG
                     LSMIPLTNPDFYHNFPTWVQTIFHSGITTGSLSAVLLNIFFNELGSKKEKNNKVEEAK
                     "
     gene            25839..26948
                     /locus_tag="KR294_001281"
     CDS             25839..26948
                     /locus_tag="KR294_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBH0239364.1"
                     /translation="MANLKVNLYGMEFLNPIMTAAGPGAKDGALCQEAAKGGAGAICT
                     KTISVLPADVPRPCMAKTNSGFLNTELWSELPKEQWIEEEYKKVKETGLPVIVSMGYS
                     AEQIAEVAPLVKPYADAVELSTHYVGTDVAPIVNALKAAKAVLDVPVFMKMSPHTDIQ
                     TIAKAVEEAGADGLVMINSFGPCMAIDVNTGYPIMGSKAGYGWLSGAPIRPLAIRCIY
                     EASQVVNIPIIGVGGITCGKDVAEMMMAGASAVQVCTEAILKGPSIYGKIAKELNEFL
                     DENGYADVNEIKGLTHKKMAARGFRTHSVAPVVDDNKCIKCKQCVTSCVYEALEVTDK
                     LNIDADKCFGCGLCVTRCPKGALSICYNQVEAMNE"
     gene            27231..28622
                     /gene="hydA"
                     /locus_tag="KR294_001282"
     CDS             27231..28622
                     /gene="hydA"
                     /locus_tag="KR294_001282"
                     /EC_number="3.5.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropyrimidinase"
                     /protein_id="HBH0239365.1"
                     /translation="MGIVLKGGKVVTSEKTYCADVRIEDEKIVDIGLDISKENDEIVD
                     VSDSYVIPGGIDTHTHFDLDTGVTKTADNFETGTKAAIVGGTTTILDFATQAKGCSLK
                     DGLEEWHEKAKDKSYSDYGFHMAITDWNDSVCNEMEDMVKEGVSSFKLYMAYKGSLQV
                     DDGVIFEALRKAEEIGGIIGFHCENGDIICELVDKAKSENNLSPKYHQLTRPAIMEAE
                     ATSRLMKIAEVANSKVYVVHLSCKESLEEVLKAKQRGVDVIVETCPQYLLLNDELYDL
                     DGFESAKYVMSPPLRNKENNEILWNAILDNQIDTIGTDHCSFNYKGQKELGINDFSKI
                     PNGSPGVEHRMSLLYTYGVCKNKISINKMVEVTSTNAAKLFGMYPNKGTIEIGSDADI
                     LVLNPNKKSKIEAKKQLQNVDYTPYEGYEVDCQIEHVYLRGKEVVRDGELICNTPSGR
                     YINRRLTKGAREW"
     gene            28616..31177
                     /gene="xdh"
                     /locus_tag="KR294_001283"
     CDS             28616..31177
                     /gene="xdh"
                     /locus_tag="KR294_001283"
                     /EC_number="1.17.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenium-dependent xanthine dehydrogenase"
                     /protein_id="HBH0239366.1"
                     /translation="MVEFILNGEKVVAKEGKKLLDFLREDMNITSVKNGCSEGACGTC
                     MVIIDGKATKACVFKTDKLAGKNITTIEGLSERERDVFAYSFASQGAVQCGFCIPGMV
                     ISSKALIDVNNNPTEDDIKKALKGNICRCTGYVKIIKAVDLAAKIFRENIDVPKVNCK
                     GLVGENLPRVDAVGKALGYSEYVDDMRIEGMIYGSAVRAKYPRALVKKIDIEEAKAYP
                     GVVAVLTAKDIPGTIKVGHLKKDWDTLIPEGEITRYLGDGIVLVAAETREALEEAKKL
                     VKIDYEELTPLSTTEDALREDAPKIHETGNILVKEHLVRGNAKEKIENSKYVVTKRYT
                     TPATEHAFLEPECAVAGPYEEDGVIIYSTDQGVFATQHECADMLGLPYEKVRVINKMV
                     GGGFGGKEDMSVQHHAALLAYHTKRFVKVQLTRKESIIVHPKRHATEMEFTTACDENG
                     YLTGMKATIISDTGAYASLGGPVLQRLCTHAAGPYNYQDIDITGTAVYTNNPPGGAFR
                     GFGVTQSCFATECNLNLLAEMVGISPWEIRYKNAIRPGQVLPNGQFADEGTAMAETLE
                     AVKEEYEKHPRAGIACAMKNSGVGVGIPDVGRCRLVIKDGKVHIRTSASCIGQGLGTV
                     MTQVVCETASLLPENVVHEVPDTHLTPDSGNTTASRQTVFTGEATKVASNKLKEALDS
                     GKTLLDLEGEEFYGEYESITDKMGCDKENPVSHVAYGYATQVVILDENGKLEKVVAAH
                     DVGRAINPISLEGQIEGGVVMGLGYALTEDYPVVNSVPTAKFGTLGLFKSTDIPEIQA
                     LIVEKNKDLLAYGAKGVGEICTVPTAPAVQNAYYVFDKEFRTELPLQNTPYSKKK"
     gene            31425..32771
                     /gene="rpoN"
                     /locus_tag="KR294_001284"
     CDS             31425..32771
                     /gene="rpoN"
                     /locus_tag="KR294_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HBH0239367.1"
                     /translation="MNFNNSLELTQSQKLIMTTQLKQSLSILNMSKLELEEEIKREAE
                     NNPLVEVEKSGEINWEEYIKDMDRSRRLDRTEISYNPDNEVNLENLVKYSSNLYEDLK
                     FQISLYKLTDKELEVCEYIIDSLDEDGYLRTEEKVIVDTLKIDEELFEKCLISVQQLE
                     PSGVGARSLSECLMIQMASLGIYNEILEEIVTKDLNLIANNKYKEISKKYNMSLQKCV
                     ELINIIKTLDPKPGRTCSVEKSVYIQPDVTVEKIDDEFIVYLNEKDSYQIRINSYYKD
                     ILKNSQSDESAKEFIKERLNSATGLMKNIESRKTTVLKIAEEIVKAQDEFLRKGTKYI
                     KPLKMKDIAEKLEFHESTISRGVNGKYMLTPFGVYEFRYFFSSAIETENNEMASSTSI
                     KKIIKETIKDENKKKPLSDDHISKLLKEKGINVARRTVAKYREELGIPSSSKRKEY"
     gene            33567..34589
                     /locus_tag="KR294_001285"
     CDS             33567..34589
                     /locus_tag="KR294_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBH0239368.1"
                     /translation="MKNLLEIQKKLIPQAIELMERRYSILRQISLSEPIGRRTLSNVL
                     EISERIIRSETEFLKEQGLIDVAVSGMTITKEGSDLLDKLKDIMSDIMGLSKLQDRVR
                     EKLGIKRVILVPGSCDENGSLLKDVTRYGCEYFLGILKDGDIVSITGGSTMLEFSNVI
                     KTDKRYPNSTIVPARGSMGTDVEMQSNNIVASISKKLHSNCKLLHIPDELDESAMKTL
                     SQVPEIKTTLEYIKRTDILVFSIGRADVMAKRRKLPEDKVDEILSKNAVGEAFGYYFN
                     KDGEIVYKLNTVGIDLETVKQVKETIAIFAGTEKVEALLAISNMHKNMVLVTDEESAY
                     KILSLL"
     gene            34649..35656
                     /gene="gap"
                     /locus_tag="KR294_001286"
     CDS             34649..35656
                     /gene="gap"
                     /locus_tag="KR294_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HBH0239369.1"
                     /translation="MVKVAINGFGRIGRLALRKMMEQQDKFEVVAINDLTDAKMLAHL
                     FKYDTAQGRFNGEIEVKEGAFVVNGKEIKVTAERNPADLPWAELGVDIVLECTGFFTS
                     KDKAEAHIQAGAKKVVISAPATGDLKTIVFNTNSDILDGSETVISGASCTTNCLAPMA
                     KVLNDKYGIEKGLMTTIHAYTNDQNTLDGPHPKGDLRRARAAAGNIVPNTTGAAKAIG
                     LVIPSLKGKLDGAAQRVPVVTGSITELVCTLGKNVTVEEINAAMKEASNESFGYTEEM
                     LVSSDIIGISYGSLFDATQTKVMEVDGKQLVKVVSWYDNEMSYTSQLIRTLGYFAQLA
                     K"
     gene            35878..37080
                     /locus_tag="KR294_001287"
     CDS             35878..37080
                     /locus_tag="KR294_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HBH0239370.1"
                     /translation="MSMLNKKTIEDIDVCGKKVLVRCDFNVPLQDGVITDENRLNGAL
                     PTIQYLISKGAKVILCSHLGKPKGEAKPELSLAPVAKRLSEMLGKEVVFAADDNVVGE
                     NAKKATEKMENGDVVLLENTRYRKEETKNEENFSKELASLAEIFVNDAFGTAHRAHCS
                     TVGAGEFLQERVCGYLIQKELKFLGEAVANPVRPFTAILGGAKVSDKLAVINELLEKV
                     DNLIIGGGMAYTFLKAQGYEVGTSLLEIDKVEYAKEMMEKAKNKGVNLLLPVDVVMAD
                     HFAPDATPIVTEDANVKEDYMGLDMGPKTIANFVKTIKESKTVVWNGPMGVFEFENFA
                     NGTLSVARAMAELTDATTVIGGGDSAAAVNQLGFGDKMTHVSTGGGASLEFLEGKELP
                     GIAALDNK"
     gene            37106..37849
                     /locus_tag="KR294_001288"
     CDS             37106..37849
                     /locus_tag="KR294_001288"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HBH0239371.1"
                     /translation="MRKPIIAGNWKMHKTIKEALEFVNEVKDKVNSDKVEAVICAPFT
                     LLKDLKEATKGTNIKIGAQNMHFEEKGAFTGEVSPLMLKEIDMDYVVIGHSERRQYFN
                     ETDETVNKKVLKALEVGIDPILCVGETLEQREAGKTKDVCKVQVEKALENVLKDDLAK
                     VVVAYEPIWAIGTGKTATAEDANDVISYIREVIKGLYGELANEVRIQYGGSVKPSNVA
                     EIMGQSDIDGALVGGASLASNDYLDLVNF"
     gene            37858..39390
                     /locus_tag="KR294_001289"
     CDS             37858..39390
                     /locus_tag="KR294_001289"
                     /EC_number="5.4.2.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003228330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-independent
                     phosphoglycerate mutase"
                     /protein_id="HBH0239372.1"
                     /translation="MMKKPVALIIMDGFGYNKDVKGNAIAESKTPNLDRIKKEYPNTL
                     INASGLDVGLPDGQMGNSEVGHTNIGAGRIVYQDLTRITKSIKDGDFFTNKVLCEAMD
                     NAKENSLHVMGLLSDGGVHSHIDHLKAIIKMAKDKGVQKVYVHAFTDGRDTDPQSALE
                     YAKEVQASMDEIGVGEFATVSGRYYAMDRDKRWERVELAYNAMVRGIGEKANSIEEAI
                     QNSYDDGKNDEFIMPTVIMKDDKPVGSIKENDSIIFFNFRPDRARQITRALVCEEFDG
                     FKREDIKNFFVCLTEYDITIENVHIAFGPQSLANTLGEYLAKNGKTQLRAAETEKYAH
                     VTFFFNGGVEEPNKGEERLLIPSPKVATYDLKPEMSAYELTDKALDKLGEDKFDFIVL
                     NFANPDMVGHTGSIEAAIKAVETVDTCVGRLIDKIVELGGSAIITADHGNAEYMLDPE
                     TGKTVTAHSINPVPFIVVGQEYESAKLLDGGRLSDIAPTVLDMMKLEKPEEMTGHSLI
                     SK"
     gene            39978..41270
                     /gene="eno"
                     /locus_tag="KR294_001290"
     CDS             39978..41270
                     /gene="eno"
                     /locus_tag="KR294_001290"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HBH0239373.1"
                     /translation="MSVIELVYAREVLDSRGNPTVEVEVVLEDGAMGRAIVPSGASTG
                     AFEAVELRDGDKGRYLGKGVETAVANVNEIIAPEIEGMDAFDQPAIDAIMIELDGTPN
                     KGKLGANAILGVSMAVARAAADEIGLPLFQYLGGVNAKQLPVPMMNILNGGEHADNNV
                     DVQEFMILPVGACCFKEGLRMGAEVFHSLKKVLGEKGLACGVGDEGGFAPNLGSNREA
                     LELIVEAITKAGYKPGEDVMLGLDVAATEMYNKETKKYVLAGEGKELTAAEMVALYED
                     WSNNFPIITIEDGLDEEDWDGWKLLTEKLGNKLQLVGDDLFVTNTERLEKGIENGVAN
                     SILVKVNQIGTITETLDAIEMAKRAGYTAVISHRSGETEDSTIADLAVAVNAGQIKTG
                     APSRTDRVAKYNQLLRIEEMVGEQARYCGLKSFYNLKK"
     gene            41863..42087
                     /gene="secG"
                     /locus_tag="KR294_001291"
     CDS             41863..42087
                     /gene="secG"
                     /locus_tag="KR294_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HBH0239374.1"
                     /translation="MSNILMGVQVVLGILLVISIMPQDSKNALPSEFGGEGSQAYFKP
                     KGKQAFLARVTKITAVLFFINALALLIVKK"
     gene            complement(42471..43409)
                     /locus_tag="KR294_001292"
     CDS             complement(42471..43409)
                     /locus_tag="KR294_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HBH0239375.1"
                     /translation="MENLILSINVVLPLFLTMSLGYVLKKLGLFDTHTLNKMNNVCFK
                     SFLPLLLFFNIYNTDLDGSLNFRLMAVAVIIIFSIFLILVFIIPKIEKDNKTRGALIQ
                     GVFRSNFVIFGIPVTISLFGDKSIGVTSLLIAVIVPMFNVLSVVILEIFRGGKVNIKH
                     MIKSVLTNPLIIASFIGLTMLILNINIPTFLHKTIGDISKIATPLSLIILGGSFSFSA
                     IKGHINPIILGVCGKLILVPAIFLPISIFLGFRNVELASLMIMLSAPTAVSSFTMAQQ
                     MDSDSELAGQIVVFTSGFSIITVFLIIFILKQNNLI"
     gene            complement(43397..43795)
                     /locus_tag="KR294_001293"
     CDS             complement(43397..43795)
                     /locus_tag="KR294_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBH0239376.1"
                     /translation="MIKKIEHVVITNNNIENYINFYKKFGFSSKEMSKNYKLNARNIK
                     INLNIKGYKFLPYVKNLQASRDNLCFKINTNIDEPKKYLEQNEIQIKRGIVECTGVFG
                     NMKSIYLKKTNGNLIELSNHRITESKPWKI"
BASE COUNT        16874 a         5294 c         7754 g        13936 t
ORIGIN      
        1 ctatttttca atgttgaaat gataaaatat atttgatttc atataaaaaa ttttcttcat
       61 aaattaaaaa gtccatttta agccccttca tttttaacca gataaatcga gttaaactat
      121 ttaaatatat tactcggatt catttgactt agatattcct tgcttgtaaa attgttttga
      181 ataggggata gccaaagcaa aaaataaaag tataatccct gctatgatta ttaaattatt
      241 aatagaaatt acatctgcca ttggtccgaa aatcatcata ccaagaggaa taaaaccagt
      301 atatataata ataggtaagc taagaactct acctagcatt tgtggtgcta catgctcttg
      361 caacatagtc atagctgatg cttgaatgat tggaattgaa aaattcgtaa aaaacataaa
      421 tataaaaaat tgccaagctt gtgttacaag acctagaata attgaaaaaa tagcatagga
      481 taatattgct agaaaaaagg tcttatttct atttttaaaa ccaccaaaaa ctcctataat
      541 caatccacct aaaaccatac ctaaaaatcc aatcatttca ataatagaca ggtatatata
      601 acccttgcca aatgttcgtt caataagaag tcctataaga aatcctgatg gaacacaaag
      661 aagcatgaat gctccataag taaaaagcac ttttctaatg aacttatctg aaaaacagta
      721 ctttatccct gataccatat ctgcaaaaaa tgagactttt tcagtttgtt ttggtatatc
      781 atgtttagga attttgatga atattaataa tacaatagca ataattgcag taaatacatc
      841 aattaaaaga acttgattta ttttattacc aaatccaagt attgcagcag ctacaatagg
      901 aactataaat tgtactatag actgtagact actatttata ccattaaaac gcattaaatg
      961 ttcttctggt acaagttgag gaatcattgc gtttacagca ggtgtttgta caccacttcc
     1021 tagtgaacgt ataacagata ttactgatat ggctattaat tcacttgttg tgccatttga
     1081 tgacatcata aatagaatta gaactaatgt agatatagca attgttgaat ctgatacaat
     1141 tatgagtacc tttcgattgt agtagtctgc ccatacacca gcaaaaaaag aaattatcat
     1201 ttgaggtata aaggagcata cagttaaaac tgttacccat acacctgatg atgtctgaag
     1261 tgtgacatac catatcattg ccatttgtac aagtgatgag ccaaataagg aaatatattg
     1321 acttgctaaa aaaagaatga cttttttctt ccatgtagaa ttagtatttt tattttccat
     1381 cctattcctc ctttgatttg tgtgttgaat ttttcttgct cttaaggata acacacaaat
     1441 caaagtctgg agttagagtg gagggctagg aaaattgttt tttcataatt tgaagatgag
     1501 atttcatggt ttttgcatta tgttcagctt ctttcaatga agttatcagt ttgtcacaca
     1561 ctgagataat ttcgtcatca tcttttggag tgtcaaggac agttttaata ttagtattag
     1621 gactagaaga taaagcattt aacattcgta aaatagctga aagagaatag tttgcacaac
     1681 gaagtgcgct tataatttta agtcgtttta tatcttcatc agtatataca cgataaccat
     1741 tttgttttct ttttactttt aacaaaccat tcatttccca atttcttaaa gtatctattg
     1801 taacgtttaa gtgttctgca gtttcttttc tagttaaaaa gagtttattt gtttctggag
     1861 tatttccatt taaaatctgt gcaacaatag taagtgcttc ctcggcatta gatttttcta
     1921 tttctaattg ttgcaagtat tgatttacaa gactaatagc cttatcaaag tccctattcg
     1981 ctgatgttct tacaatctca agggcatctt ttcttaatcc cctttgtacc acttcaattt
     2041 tcaaggctgt acgagcaaat ctaaattgtt ctatatgaaa atcattaaag atacgataac
     2101 cattggtatt acgcttaggt ttaggtatta agtttagttc ttcatataaa cgtactgtat
     2161 taggatgtac accaattaaa tctgctacct ctgatgtcgt gtaagtgtcc attagtattc
     2221 aactcctttt agatatatag tattagtcat aataacacca aacaaaagtc tggtgttata
     2281 atggagggtt tggctatcta agagtaatta gtttatgaaa gagtaattag tttatgaaag
     2341 agtaattagt ttatgaaaga gtaattaatc tattatagaa gtaagtatat atttttcaat
     2401 gaactcccat ctatcacgag gtttaaacac tattttagat ggtatggcta ttactaagtc
     2461 atattgtgga atacaacaaa tagcatttcc tccagttccc attgctgaat accacaaaac
     2521 accatctttt ttacatagcc accacagata accgtattca ttactattca ttttaactga
     2581 ttcttcaatc cacgatttag atataatacg tttattattc caaataccat catttaaata
     2641 cagaaaacca aatcgcaaca tatctctagc actcaatgta agtccccagc cacctataga
     2701 ataaccctgt ctatcttttg cccaaccctt aagatttttt ccaaagaaat cttcaaaacc
     2761 aaaatctttc atatcataat ctggtataac tttcatacca ataggtttaa ataagtactc
     2821 attagcaaat tcacgagcag attttccagt agtttttgtt ataatagctg aaagtaggtg
     2881 cgttccagct gaagaatatt tgaaagtacc aatttcgcct ttttgaccaa gttgattcaa
     2941 ggtatatttt atccaatctt tttgtttgca aagtctttct aaagactcag tcatattttt
     3001 aaaagggtat ggtgcagtca ttgtaagtag gtgacgtata gttactgctt ttttacatat
     3061 ttcagaagga ctacaagtat attcaggaaa aaaatcaaca accttttggt caacatcttt
     3121 tatatatcct ttatctattg caatacctat taaggctgat ataatacttt ttgtaactga
     3181 tgcaacatga aaagtatcat cagcattata tccattatag tacttttcaa agacaatttt
     3241 tccttttctt gcaataatta taccatttat attgctatat tgtgagatta ttaaaggttc
     3301 aagttgtgaa agcttttctg aactcatacc aacacttgaa gggtctactt tttcaaaaat
     3361 taagtctaag caattgtttt tattcattaa agatacctcc ctgttataga ttttggattt
     3421 tcttttagag tttttggaga accttctgca attatataac ctcctttgtc accaccttct
     3481 ggaccaagct caacaatcca gtcacaaaca tttaatacat ctatatcatg ttcaacaaca
     3541 attacagaat ttccattttc aaccaattca tctaataatt gaatcaactt agaagtatca
     3601 tatagactta gaccagtagt tggctcatcc aatacataaa ggatattacc atttcgtttt
     3661 ttaccaattt cttttgcaag tttgattctt tgggattcac caccacttaa agtcggtgta
     3721 ggttggccta attttatata ccccatacct atttgttcta atacatttaa gtgtgaaaca
     3781 atatttggaa tatctttgaa gaaatgtaca gattcagaaa cactcatatt taaaatatca
     3841 tgtatatttt tatttttata tttaatagat aaagattcat cattaaatct ttttccctga
     3901 cattcactgc atatatggtc tatacttaga ttatttccca accagacctt ttcatatcca
     3961 ctaccactac atttaggaca agcccctttg gagttaaatg agaaatgacc agctgtaaat
     4021 ccttgttcta acgattctgg ctgacctgca aatagtgtac gtatcttatc ccatatacca
     4081 atataagaag caggagttga gttcatattt ttgcctatag gagattgaga tatctctgaa
     4141 tatccagaaa tatgtttagt accaatcagt ctatctgcaa tagtttcaac aactgcataa
     4201 tcgtcttcct cacctatttc actctctgaa gaatttattt gattattgat agtatggtta
     4261 ttaaattggc ttctaagaag aggaagtagg gtgtctgata taagtgaact cttgccacta
     4321 cctgattttc cagatattcc aaccatagca cccaaaggta atgatacagt tacattttta
     4381 agattatttg tatttgcatt ttgaatagtt atacaaggta ttttatcagt atgtgtaatg
     4441 tttttattgc ttgttctatt aggcattgga tattttccag atagatactg tccagtaagt
     4501 gatttgtcgg attgaagtag accttctaaa tctccttgat atactaattg accaccttca
     4561 acaccagctt ttggaccaat atcaataata tgttctgcca tttcaattgt gtttttatca
     4621 tgctcaacta ctatgaccgt attgcctaaa tctttaagtt tctttagtga ttttaagatg
     4681 tctatttttt ctgattcatg caatccagct gttggttcat caagcacata aattaatgag
     4741 tccatctctg aatcgagatg tgaatttaaa aatagtcttt gcatttcccc accactcaaa
     4801 gttgacattt ctcggtataa ggatagatga cctaatcgtg attctattaa atgttgagtt
     4861 ttggataaaa tatcatttac aagatttgta ccaaatgtgt ttaaattacc ttgatttatt
     4921 aagagtttaa ggaaatcatc aatttctaaa atcgtcattt ttccaagttc tccaatatgt
     4981 tttccgttta aaagtactct acgtgcttct tcaccaattt taaaaccatt gcaatctgaa
     5041 caggcagtca tagtataaac tccatttaaa tcttcgcccc ttttgtaacg attgtgaaat
     5101 acctttgata aagaggaact ttttttacca ttttcataat gaccatagag tacttcattt
     5161 cttatttctt caggtagttg taagaattgt atgtctaaat aatcattgaa ttttttagaa
     5221 aatactctca aatatccagg tgtaatcttt gctctatcta agacttgttt tagggtatca
     5281 tgcttatcaa ggactaattt ttcaatatta atctcaaaat atgcaccatg tccagagcac
     5341 ttcatacaca ttccatctga agagttgtat gagaaataac ttggtcttaa tcgttcttcc
     5401 tcatatccac aattattgca aattagatta tcgcttacag gagtatcaca catagtacac
     5461 attatttgac cttccactga atacaatagt gtaagcatgt tgagaatatt ggttcttgtg
     5521 cctactgttg aacgaggatt gctctggcga ataatatttt gttgaacagc tatagtggga
     5581 gctaaacctt gaatattatc aaacttatct tcactatcaa tacctgcaag tatacctaaa
     5641 gattgcagat attgtttacg cccttcctca aatacaatgt caaacataag gctagactta
     5701 cctgagccac tgacacctgt tgcaacaaca agcttatctt ttggaataga aacatctata
     5761 tttttaagat tgtgtatctt tgctccatta atttttattt ctttcattgg ttcacctcat
     5821 tttatcaatt ttatcaaacc gtaaaatagg gatatattaa tccttaatac aagaatagat
     5881 taggtgaggt tattaaaaag gttctatagg taaatatata tcgaccaagt gtctattttg
     5941 agggtgattg tgtgggttgt taagatatac ttcaaaaggg aaggaggcac gtagcttata
     6001 attaccattt gatagccatt cattatacat aaaatcccac gcatcactat attcagattt
     6061 tgaaatatca aaatgtccca caagatattt tccagaaggt attatcatat tgccaagatt
     6121 gtcattctct ttgacaacaa tgttatctgg aatggtcatg caaatactag tccttaattg
     6181 atgctcctgt gtaaattgtg gattatcatg ataaatggct aatatttgtg tgttttcaag
     6241 tccaagtaga ttctgctcac ttgcatatgt gaataaccgt tctaaaagtt ttgggaaagt
     6301 actggttaga ttaccatatg aaccagtata tctagtgtaa atagtattca tattatcaag
     6361 ttctagaatt tcaatttcac ctttaacctc tctagtattc ttacatttag gttttgatat
     6421 gcttctattg tactgagaaa ttttatatgg ttctttgcaa ttcttgctat aattgtttct
     6481 atattttata gggcttattt tatagtaatt tttaaatgct ctcgagaaaa ctgctgaatc
     6541 agtaaagccg aagtagtgtg caatatcagt aacagtcatg tcagttctat gaataagaaa
     6601 agcagttgca ttttctagtt ttagcctatt tacatattgt gccaaagttt ctttttctat
     6661 tgctttgaag attctatgaa aatgaaattt tgaaaaacct gctatattag aaagttcatc
     6721 aagagaaaga ggttcatgta aatgttcttc tatatagtct tgcactttgc aaatacgatt
     6781 tagatattct tttttacttt tagcatttgt catatatagc cctccttatt gtgtaaaatg
     6841 tgtatcaatt aatttatagc aatatagtaa taaaatttta tgtttttgta atttatgata
     6901 aataagatag cgtttaattt tttataattg ataaaagata taagatgcct tatatttgtc
     6961 tttgcatata agtatagtct tcgtaataat tagtatacca tagtgattta tttttaattg
     7021 tgtatttata taaatacaca acttatgata tggacgaatt attatgcaaa taagctgtaa
     7081 ttaaataaat tgcaatataa accagttgaa acataagtta gggaaatatt atcaaagtta
     7141 ttacttagca taagagtata gatggaataa aataagatta aaaaattaca tactaaattt
     7201 aataaaattt ttatattaaa aataatatta agtttattgt ttaaataaaa aagttaaatc
     7261 tacactatta acttattata cttaaaactt taaaatgaaa atatcaaaga atacttttta
     7321 ataaaaataa tcatttaata agttatttaa aaatctaaaa actttacaac aaattatata
     7381 tttaaattgg aggagtggga atatgagtaa tagtttttat caattaaatt cagcagtatt
     7441 atattttaat gaaaaaagag atgtaaatag aataaggttt aatcactatg taatgagaaa
     7501 agaaaatata caaagattaa aaggaactct gccaagagga caatttatga tgacagtaag
     7561 gaaagctgca tctgaccttg atgtatctat atctacaata agtagacttg taaatgaatt
     7621 tatagattta ggtatattga gattaataag taggggagta aagggaaatt gttgttctgt
     7681 atatagttat gtttgttctg aaagtagtaa tgcagaaatt gtaacaaaga atggtgatat
     7741 tttcaaaaat atagagaaat acattgatgc aactattaac aataaccaaa aaacaatgaa
     7801 atataaacat agaaatgagt tgtttaagaa cagtaatacc aacatataca gccgtataaa
     7861 tcaagagagt atagacaaag attatgattt gataattcat actgggtatg aaacagaaaa
     7921 tgagacaaag aaaaaagaat tattaaaaaa taatttaaat aaaaagaatt taaataaaaa
     7981 tacctttgaa aattcggatg aagatttgac tgaagattct acttacaaaa atccagaaag
     8041 catacatgaa attattataa gaaaattaaa tagtgaatca ggaaaaaatt ttaaagctga
     8101 tttgagtata actaaggcac ttatagataa aagattaaaa gaagggtata gtttagaaga
     8161 tttttacaag gttatagagg caaaggtaag aagatggaga tatacagata tggaaatata
     8221 tatagaacca acaattctgt ttgggtatga atttgagtcg tatttaaatg aggagagttc
     8281 tttatctgct tgtaattatg gtgatatgtg ttatgaagat atgtattgag atatttatta
     8341 agatattagt tgctttttag ttgtttaaaa tatgtttatg tataaatagt gtattaaaat
     8401 ggagttgtct caaaatagag agaagtctct tcttaattgt ttaaatgatg aaaatatatt
     8461 tgatttaata caaaggagag tgctttatga gttagaagat ttattttgag acactcactt
     8521 tttttaatat actggagaaa tataacccat tttacaagag tgcatagata tatataatgg
     8581 cataatgtgg atttaaatta aaaaaataaa ataaagccat aaatattgaa aatttcaata
     8641 tttatggctt tattgcttgt aataattaat agaatatata ttttttatta atcatctatt
     8701 tatatttttt attaatcatc tatttcaaat tctaatattt taccagtaat tgcattaatt
     8761 gttatctcat attcagtttt tccttttatt atttcacctt catattcttt gtcatcttca
     8821 tcatacttaa attttactat tttcccacca ggcactttat ctagcattat tgatttagct
     8881 ttttcagcac taataataga actgttgtca ttagtattag agttattctt atcattatca
     8941 tcaaagtcat catcagaatc attgtccatg tcaatatcta caattcttcc atcaaatgca
     9001 cttatctcta attcatatgt tttcttattt tttattactt tagcctcata ttcgttatct
     9061 tcagcatcat atttacaata gattaaatta ccattaggaa tagcatctaa tgctatagac
     9121 ttagctttat ccaatgatat attttgtgta cctaaattat tatcatttaa gtcatcatct
     9181 ttttcaattt ctattatttt accagagtag gcatcaattt ctatctcata taggatatta
     9241 tcctttataa ctttgcagtc atattcatta tcatcttcat cataataaca aactaaaata
     9301 ttgcttcctg gaagagcttg ttttaatatt tctttagcct gtattaaaga tattttttta
     9361 gttttatttc ttatgttcac attttttagt tttaaaatat cttcaaatgc tttttgatta
     9421 tatcctcctc ctacttgtgt tatttcatct atatctttat ttttaataaa ttctttttga
     9481 ctatttacaa ggctaccatt agatatcatt ataggagaat tttctttagc agctagtact
     9541 cctattgata atgaatctac taatgcattt tcttggttaa taccatcttt agctacaaat
     9601 acattattta tttttttatc tttataaaat ttatcaataa tttttgcatt agtattgttt
     9661 ctatctgaac cactgattct ttctctgttt ggatatttct ttactgtatt gtctgataaa
     9721 atcttatttc ctccaactat gtaagatttt tttatagacc tattgtttaa gaaatttata
     9781 ctactatcat tgctgttttc atctgatact aatattatag gcatattatg tattgctgct
     9841 ggagaagcta tactaactgc atcagatagt ccctttagtc catttacaac tgcaacattt
     9901 tctatctttt ttatcttatc tatttcttta agtacatttg tagacatttc atatatattg
     9961 tttcctacta ttttatttat ttttatgtta agtgatttta tttcattttc tactttagaa
    10021 gaaatgctat ttccactatc tacaatgtac acattatcta caccaagcct tttaagctca
    10081 gccttagttg aattttcaat actgttgttg tttactaaaa gtataggtgc attctttagc
    10141 ttagcaaatg gatttgcaca aagcgcactt tgaatagaat taccattaac tataatggct
    10201 gtttttgatt gaacccatcc caatttactt acttctactg ctgtttcata tcttgtttta
    10261 cctattaatc tttcttgctt tgtagtattg tctgcaaaaa ttgctgaaga actagaaaaa
    10321 aacatcatac ctgatattaa tatagctaaa tttttcttat tcatattttt acctcacaat
    10381 ctttaaaaat ttgttattta gcatacttaa taaaatataa tcttaaaatc aaattgatac
    10441 tgagtttgaa gttacaaaat caacaaataa gatttcttta atacaaaatt ttccttttta
    10501 tatttaacat tgtatcacaa atataaaaag gaaaaaactt tttaaaaagg gtatacacta
    10561 ttcatttttt atcttataaa taagtcttta tcactgtttt atatatttta aaatagacac
    10621 aagacctatt tctaaatctt ttataaatat tttaggtgaa atttcttttt aaacatatct
    10681 aaaaagtatt tgtagtaata ttaatggact gaatttctta aagtatatat ttctttacat
    10741 gttggagttt gtgaagtttg agaattggag ggtgaaagaa acatgtaatg gattaatatt
    10801 aaagaactgt atttttataa tatttgtctt aaaaataaaa aaatctattg acttgaagtt
    10861 aactccaagt agtaaagtat aattatacaa gaattatata cttgtaagaa tagttaaagt
    10921 agagagaaaa aacaaacaag ttttaaaggg ggaagtaaaa caatggaggc aaaaaaatta
    10981 ggatttggat taatgcgttt accaataaaa gatgaaaatg atgttacaac tattgatatg
    11041 gaacatttaa ataaaatggt agacactttt ttagaaaggg gatttacata ttttgatacg
    11101 gcctatgtgt atcacatggg aaaaagtgag atagcactta gagaatctct agtaaaaaga
    11161 cacaaaagag agagttttac tatagctaca aaacttccat taatggcttt aaagaaaaaa
    11221 gaagagcaag aaaccatttt taatgagcaa ttagaaaaat gtggtgtaga ctattttgac
    11281 tactatcttt tacacaatat aggcgtgtca cattatgaag tagctaaaaa atttgatagc
    11341 tttaagttta ttgaagaaaa gaaaaaagaa ggaaaaataa agaatattgg tttttctttt
    11401 catgatagtg cagaattatt ggataaagtc ttgagtgagc atccagaagt agacttcgtg
    11461 caattacaga ttaattattt agattgggat aatgaaagca tacaatctag aaaatgctac
    11521 gaggtggcag agaagcataa taagcctgta attgttatgg agccagtaaa aggaggtaca
    11581 cttgcaaaga taccagaaaa agcagagaaa ttattgaatg actacaatcc agatatgtca
    11641 atttcatctt gggcaatacg ttttgcagca agtaaagata atgttatgat ggtcttaagt
    11701 gggatgtcaa atatggaaca attattagac aatacaggat atatgcaaaa tttcaaacca
    11761 ttcgtacaag aggaatataa tattatagat gaagcagtag agattatcaa cgaatcaatt
    11821 ttaattcctt gtactgcctg tcagtattgt gtagaaggct gtccaaaaaa tatcgctatt
    11881 ccaaactatt ttgcgttgta caatgcagaa aaacaagctc ttaatactgg attttcaaca
    11941 cagatggtct actataataa ttatactaaa acttatggaa aggcctcaga ttgtattgaa
    12001 tgtaaacaat gtgaagaaag ctgtcctcaa cacattaaaa ttatagatgc tttaaagaat
    12061 gtagcagaaa cctttgagaa ataattcaat ctatacaata tcaagaggag aagatatgta
    12121 tgacgatttc agaagttagt aaaaaatacg agctttcagc ggatacttta cgatattatg
    12181 aacgaattgg tttaatacca cctgtaaata gaaataaaag tggaattagg tcttttacag
    12241 aagaagattg tgagtgggtt aatttcataa agtgtatgag aggtgcaggt ctttctattg
    12301 agacattaat tgagtatgta gctatgtttc aacaagggag cagtactatc aaagctagaa
    12361 aagaactttt aatagagcag agaaaccaac tagcaaaaag aatagaagaa atgcaaaaaa
    12421 ctttggaacg attaaatttt aagattgata gatatgaaga aggtattatt gagaaagaaa
    12481 aagtattaaa gagcagtaga aataagaaaa tggaggcagt atcttatgag taaaaatgta
    12541 ttaatagtat cagctagtcc tagaaaaggt ggaaattctg atttattgtg tgaccagttt
    12601 atacaagggg tattagaatc taaaaatcaa gtggagaaga tatttttaaa agataaagat
    12661 attaactatt gtactggatg tggtgcttgt tatgaaaaag aagcaaattg ttcacagaca
    12721 gatgacatgg gagaaattct tgaaaaaatg attggggcag atgtgattgt tttagcgact
    12781 ccagtttatt tttatactat gaatgcgcaa atgaaaacta tgattgatag aacttgctct
    12841 agatatactg aaatttgtga taaagatttc tattttatcg ttacagcagc agatgaaaat
    12901 gtggctgata tggaaagaac aatagaagga tttagaggat ttacatcatg tctaaatggt
    12961 tctaaggaaa aaggtatagt atatggtgta ggtgcttgga atgtaggtga tattaaggga
    13021 agtaaggcaa tgaaacaggc atatgaaatg ggtaagttgg cgtagtatgt ttgtataaaa
    13081 ttgtataaaa ttgaatatat tcttatcatt tcaacaataa aaagaggctt atctgtattt
    13141 tgagacagcc tctttgtgct atatcattta tttttattct atatccttat tatacccttt
    13201 atttttttat gcctatttaa gtatctgttg ttactcatat attttaataa ttacccttaa
    13261 aaaactatac agattcctgc ataatattat tttctttagt aattaatttt tctaggtttt
    13321 tccaatccat ttcttccata tttgcaaaat aatgaccact tcctatgcaa gtcaggtaag
    13381 actttccatc taattcaaac gaagaacctc caatacactt tgaattacat ttcttacaag
    13441 tacgagtttt agttatacta tctttaatag ttttagagca ttcctccaca gcatctttat
    13501 atgtatttag atgaaaaaga tttgctttaa ctctccattt tttttcatta cattcaatag
    13561 taaataagct acgttttggt ttcttagttg aatatactat tttgtaagaa cgagcacctg
    13621 tttttggttc aattttacaa tctaatgatt taccaagttc atgtaaatga catgcaatat
    13681 cataatcttt accacttagt acttctaaca tttcttctgt tgtttctgct gttaattcac
    13741 ttttgctcat attaaaaaaa tccccctata taaataataa tttcatatga aaataattaa
    13801 tataagtata ttaaataaaa ctattaaaat caataaaatt actgcaatct tacattattg
    13861 ggcatagaat gagagctaat gatttattag aaataagact taatagtatg aaaatttact
    13921 tagacgtggt acaattctat aaaagattta aaactaggaa aggagaaagt tgttgagata
    13981 cggccaatat aacaatttat ttataagttg taaatttatt atgagattaa ttagattgtt
    14041 aagtaatact atcaaaaggt agttttttgg attttcagca acagtggtag atattgataa
    14101 ttttttggtt attattatat ttagctgtta tattttcaat aggctctatg ataactaggg
    14161 taaataaggt atgggtaaag gttttattat ttataatagt gggattgtca actatagttc
    14221 tttcatatgt aataacttga ttatgcaaaa ttctatgaag caggaaccct gtgactttag
    14281 tcatgggagg ttcagaattt aaggttaaaa aataacttta atctgtaaat tctcaaaaca
    14341 agaattctca tgttggtaaa tttctagata tgagaaaaaa attgacatca taaaaaagta
    14401 attttagagc gtttttttac gaaaaaattc agaagtaact attttgaatg acttcacaaa
    14461 attttatata taaataaagt ttggcacgtt aattgcttta ataaaagtta acaagacaca
    14521 aataaacata atcatctaag tattgattat ttgaagtttt agatttgaag tttaatctaa
    14581 aggttcgtat taatattggt gtttaggaaa ttttattttc ctgtaaatat aacttaataa
    14641 taggaggtga agtcatgtca aaagtagtaa tagctacaga gaaagctcca ggagcaattg
    14701 gaccatattc tcaagcaatt caagttggaa acatagtttc tacatcaggt caacttccaa
    14761 tagatatgaa gactggcgag ttagtatctg acccaaaaga agcaacaaaa gcttctttag
    14821 ataatgtaaa agcaatatta gaacaagctg gtacaagtat ggataaaata tttaagacta
    14881 cagtattcgt aaaagattta aaggatttta atgatattaa tgaagtatat gctacatatt
    14941 ttaaagaaaa tccaccagca aggtcatgtg tacaagttgc tcaattacca aaagatgcag
    15001 ttttagaaat tgaagcaatg gcagtattat aagtattata acaataaaac caataacaaa
    15061 actaataaaa attaaaaact aataaaaaaa gtctacaatt aaaaaagttt atattaaaaa
    15121 agtctatata aaaatctatc taaatattta actattgagc ttttctcata taatgtatat
    15181 ttttatgtca aaaatatatt tgttatatga ggaaagcttt tttttattat tgtattgtga
    15241 tttattttat tgtctgcata ttataattaa ggttactata taaaacaaac tttttataaa
    15301 ttaatattgt ctgttttaac gcaaatatat aaataagtaa tgttttatat atattttaaa
    15361 gagtgactat atgttaaaat atagctaaac tgataatttg gtaaattaaa ttctaatggg
    15421 ggaaactatg ttaagtaaat taaaagaatt tcaacaagaa atgataaaat acactgaaac
    15481 agtagctagt gtgttagatg tagatattga aatagttgac gatagattaa taagaattag
    15541 tggtacaggt ctgtataaat caaagataaa tgaaagcgtt gttactgagg gctttattta
    15601 tgacaatgtt atacagacag gtcaggaatt agtcgtattg gatatatgtg ataatcagct
    15661 ttgtatagaa tgttcccatt acatgaaatg cctaaataaa gtaataatag cagttccaat
    15721 aaagtataat aatcgaacta taggagtaat tggtgctatt agcacagata aaactaaaaa
    15781 agtagaaata agtgcaaaaa tagataatta tttaaaattt gtcaatcata tatgcgattt
    15841 aatttctatg aaaatagaag aacatgaagc gtcaaaaaat agcagtagaa aaatggatat
    15901 gatgatagaa atcattgaaa atgttgaaaa aggcgttata atactagaca taaatagcaa
    15961 aatatcttat ataaacaata tagctctaaa aaaattagat atagataaaa atataataga
    16021 aaatatagta aatatagtat ctgttgaatc ttcctcaaat ggacatgaat tactagaaat
    16081 tgatattgat aacaaaattt ataatataaa tgccaaaata attccggtat atccatatat
    16141 aaatcaatac gacaaaataa taatatttga caagacatat atcaatcata aaggacatgg
    16201 aaaagtgaat agtggctggg gaaatagtga tatagagtct ataattggaa attcagaagc
    16261 aatgttaaaa gtaaaagaga gaactaagaa attagcaaag tcaaattcaa ctgtacttat
    16321 aactggggaa agtggtacgg gtaaagagct aattgctagg gctatacatg ctgaaggtag
    16381 cagatggaac aagccattta ttgcgataaa ctgtgctgct attccagaaa atctccttga
    16441 aagtgagcta tttggctata taaaaggtgc atttagtgga gctagtagtg gagggaaagt
    16501 aggtaaattt gaacttgcaa atgaaggtgt tatatttctt gatgaaatag gagatttgtc
    16561 aatgccttta caagcaaagt tacttagagt tttacaagag agaaaatttg cgagaattgg
    16621 gtcaaataaa cttatagatt tagatataag agtgattgct gctacaaata aaaacttatt
    16681 gaaattagta aatgaaggta agtttaggga tgatttatac tatagattga atgtaattcc
    16741 tataaatttg ccacctctta gggaaagaaa ggatgatatt gaggcaataa tgatgaagtt
    16801 tgcttctaaa tattctttag aattaggtat tcagttaaat aaaatagaag aaaatgtaat
    16861 gaatatgttg attaactata attggccggg aaatataagg gaactggaaa atgcagttga
    16921 atatatgatg aatttggttg gagatgatgg aataatatat aaagatatgc ttccattaga
    16981 tattttaaac tattataata ttaatggaaa tatttataaa aataaggatg taaatataat
    17041 atttgaagat gatatagttg gagggatagt agagaatcaa gaaaggatac tttcaattaa
    17101 agaattagag ttgacttaca taaacaagtt gttgaataag tatggaagag atacaaagac
    17161 gaagaagaag atagcaaaag acttaggcat aggtttggct acactatata gaaaattgga
    17221 agaggaacag tagtaatata atattaaaat gataggtatt tgtgtgtttt tatagatagg
    17281 tatttttact ttatggtgga ggtgttatta tgcaatatgc gatagagcta tattatgata
    17341 aaaaaacgga aaagcaactt tttgatttat ctaaaaaaat cgctgatgaa aaaattagta
    17401 cgaagtactt agaatggaaa acaagacctc atcttacttt ggcttgtttc aatgatgtgg
    17461 atgaggcttg ttgcatagac aagctaaagg ggtttgcaca aaaccataag gtaatacctg
    17521 cttacattgg ttcagtaggc atgtttaatg atactaaaac ggtgtttgta tcacctataa
    17581 tgaatagcaa tgtatcagtt tcagagagaa ttatatgagg tactacaaga ttttgattca
    17641 aatggttggg aatggtacca ccccaatcgt tgggtacccc attgcacaat agcacttact
    17701 ggagatgatg aaagtgaggc tttttttcgg gcaagtgatg tattactgcg tgagttcaaa
    17761 aaaataagtg gtgagtttgt ctcaatagga ttggttaaaa ttacatttcc tgtggaagaa
    17821 atttttacag tgaatatgaa taggtaactt taactctgtt gtggatgtta tgaatatttt
    17881 gtatagtgca tttcatcaga taaatgcgaa gttgcgaatt tcgacagctc aatagtcgca
    17941 agtagggcac aatggtacac atattgcact tttgcttatt ggggggacga ccatgtaaac
    18001 ttctgtaaga agctatgaaa agatttaagc cattttggag gctttgggta ataaagaata
    18061 tttgggtaat aaagtatata aatttataga gtttatgcgt aagaaggtta tagccatata
    18121 tttatagaaa ataaaagtag taatatatct gacaaaacaa tagacatata aaaaataaga
    18181 gcataataaa ggaagaatta agataaataa acgatttctc gaattgataa ttctcgtatt
    18241 gataaaaatt tcccaatatg agaatttttt cttttataaa tcttattttt cacactcaaa
    18301 atttataaac tttaaagaaa ttttataaaa gtatgtaatt ccaacataaa aaaattgttt
    18361 ttagaataaa taatattggc acggtaattg ctttgctata aggcacaaag ataaaaaatt
    18421 aaaatgacac cgaaaaattt gaaaggggaa tataaaataa atgagagaaa taaaatggaa
    18481 attaaataac ttacctaaat cagaggaaaa agaaaaagga attgaatttt taaaagatga
    18541 agagattgca aaggctaaag cttttcatga aagctttcca caatatgaaa agactccttt
    18601 agttaaatta gataacttag caaaatcact aggcgtaagc ggaatatatg ttaaagacga
    18661 atcttataga tttggcttaa acgcatttaa agttttaggt ggttcttact ctatgggtag
    18721 atacttagct caaagattaa atacagatat atctgagtta gggtatgaca aattgacttc
    18781 gaaagaaata aaagaaaaat taggagaaat aactttcttt acagctacag atggaaatca
    18841 cggtagagga gttgcttgga cagctaataa attaggtcaa aaatctgttg tattaatgcc
    18901 aaaaggttct tctgaattta gattaaataa aatcaaagga gaaggtgcag atgctagtat
    18961 aacagactta aactatgatg atgcagtaag attagctaat gattatgcag aagctgatga
    19021 ccatggagta atggttcaag atacagcatg ggacggatat gaagaaatac cagcatggat
    19081 aatgcaagga tatggaacta tggctaaaga agctatagaa caattaaaag aatatggagt
    19141 agatagacca acacacgtat ttgttcaagc aggagttggt tcacttgctg gtgcagttca
    19201 agggtatgtt gcttcaatat atgatgaatg cccaataaca gtagtagtag aggctgatga
    19261 ggctgattgt tactataaat cagcagaagc tggagatgga aaaccaagat ttgttggagg
    19321 agatatgcca actataatgg cagggcttgc ttgtggagaa ccaaacacta taggttttga
    19381 agtgttaaaa aattattcat cagcattcgt ttcagcacca gactgggtat ctgctaaagg
    19441 tatgagaata ttaggaaacc ctctaagagg agatgagaaa gtaatctctg gagaatctgg
    19501 agcagttaca actggagcat tagtttcaat ccttgaaagt gaagatttaa aagacttaag
    19561 agaagctttg aaactagatg agaactctaa agtattatta ataagtacag aaggagatac
    19621 tgaccctgat aaatatagag atatagtttg gaatggtgaa tgccaaagta aataaaagac
    19681 ttaaggaaaa taaaaactta acaaataaat gaaaaattta aggaaaataa aaacttaaat
    19741 aagtgaaaac tttaaataaa ataaaaacta aaacaaatga aaaatctaaa taaatgaaaa
    19801 agtaaagcaa atgaaaaatt caaaataaaa actaaataaa attaaataaa accaaataaa
    19861 attaaaataa agtctaaata aaaatttaat aaataaaata taaagaaata aaaaatcaat
    19921 agattaagtg aaatgctaat aaattaaaaa agtgaaatat caaaataaaa cgtcaacaaa
    19981 ctaaaaatta tatgggggaa tatcaaaatg ttaaatgaaa caagaaaaaa acaattaact
    20041 gaagtatgcc aagacttaat aagaaatgct agttattcag gtcaagaaga aaacgtagta
    20101 aaagctatag aagaaaattt tgctttacta ggttttgata gttggtcaag agatagatat
    20161 ggaaatatag taggatgtat aaaaggaaat aaaccaggta aaaaaatatt atttgacggg
    20221 catatagata cagttccagt tccagatgca agtaaatgga gtgttcctcc ttttgaagcg
    20281 agaatagtag atgggaaaat atatggtaga ggaacttctg atatgaaggg gcaagtaagt
    20341 gctatgatgg ctgctgtttc atactttgca gaagatacta acaaagactt tgaaggtgaa
    20401 ttgtatgtag caggtgttgt tcatgaagaa atatttgaag gtgtttcagc tagagagata
    20461 agtaaggctg ttcaacctga ttatgttgta ataggtgaat cttcagaatt aaacttaaag
    20521 ataggtcaaa gaggtagagg agaaatagta gtagaaactt ttggtaaacc agctcactct
    20581 gctaatccag aaaaaggtat aaatgcagtt tataaaatgg ctaatgtaat ccaaaagata
    20641 caacaattag tacctccaac tcatccagtt ttaggtgatg gaatattagt tttaacagat
    20701 ataaaatctt ctccatatcc aggagcatca gtagtgccag attattgcaa agctactttt
    20761 gatagaagat tattagttgg agaaacaaga gaaggcgtat tagctccaat acaagcttta
    20821 ttagatgaaa tgatgaaaga agacccagaa ttaaatgcaa aagtttctta tgcagttgaa
    20881 aaagctgatt gctatacagg aaatactata gaaagtgaaa gattcttccc aggttggtta
    20941 tatgatgaag aagatgaatt tgttcaagca gcgtataagg gattaaaaga agctggaata
    21001 gattcagaaa taactcaata ctcattctgt acgaatggaa gtcactacgc aggtgaggct
    21061 ggaataagaa ctataggatt tggtccttct aaggaaaatc ttgctcatac aatagatgag
    21121 tatatagaat tagaccaatt attcaaaggt gcagaaggat attatggtat attaaaatca
    21181 gtttataaaa aataattagg agatggtttt gtgagaactt taataaaaca tgggcttata
    21241 gtagatggaa ataaaacacc agcatatgaa ggagatattt taatagaaaa cgagaaaata
    21301 ttaaaaatat cacaagattt aaacgaagaa gctgacaaag ttatagatgc aaaaggtaga
    21361 gttatatgtc caggtttcat agatactcat agccattcag acctagttat tttagttaat
    21421 ccatataatg aggtaaagat tagacaggga attacaacag aagtgttggg ccaagatggt
    21481 atatctatgg cccctctacc tcaagagcat atatcttctt ggagaaaaaa tttagcaggt
    21541 ctagatggtg aaagtgatga aattgattgg aaatatgaaa caacagagaa ttatttaaaa
    21601 atgatggatt acaatggggt aggtttaaat gaaacttatt tagtacctca tggaaacgtt
    21661 agaatggaag ctatgggact tgaagataga cctgctacta aagaagaaat tcaaaaaatg
    21721 tgtgaaatca cagagagaga attaaaagca ggagctatag gattgtctac tggacttata
    21781 tatatacctt gtgcatactc attgactgaa gaaattatag agatgtgtaa ggtagtagca
    21841 aaatatgacg gagtatttgt agttcaccaa agaagtgaag cagatacaat tttaacttca
    21901 atggaagaaa tcatagaaat tggaaaacaa tcaggagtaa aagttcattt ttcacatttt
    21961 aaggtttgtg gtaaagcaaa ctggaagtat ataccacaag ttatagagct tttagaaaaa
    22021 gcagaaaagg aaggaataag agtatctttt gaccaatatc catatgcagc aggaagtaca
    22081 atgcttggag tagttttacc tccttgggca cattctggag gaactgataa gttaatagaa
    22141 agattaagtg atgaaaacga aagagcaaaa atgaaaaaag atatagcaaa tggaatagaa
    22201 ggctgggata attttataga atttgctgga atagaccaaa tatttgtaac aagcgtaaaa
    22261 acagaaaaga ataaagatac aattggtaag agcttattag aaattggaaa aatgagagga
    22321 aaagacccat tagatgcaac gtttgattta ttaaaagaag aagaaaatgc agttgggatg
    22381 gtagatttct atggattaga agaacatata ataggattca tgaaaagaga cgagcaaaat
    22441 gtgtgtacag atggtctttt agcaggtaaa ccacatccaa gagcttatgg ttctttccct
    22501 aaaatactag gaagatatgt tagagagttg aatgtgttaa caatcgaaga agctgtttat
    22561 aaaatgacta aaaaggcagc tacaagcttt agtataaaag atagaggcga attaaaagaa
    22621 ggatattttg cagatatagt tatatttgac aaggatacag ttagtggttg tgatgatttt
    22681 atcaactcta tgcagtaccc tacaggtata gattacgtaa ttataaatgg aaattgtgtt
    22741 gttgaagaag gaaaatacaa taaaattaaa gcaggaaaag tacttaaaaa ttaaatctta
    22801 gctttaagga ggaataaatt tatgatttta gtggggaatg ggaggctaat aagccaagat
    22861 tctttaaatc cctatatgga agatggatgt gtagtaataa atgataatct aattgaagat
    22921 ataggtacta cagaagaaat gaaagctaaa tatccagtac atgaatttat agatgcaggc
    22981 aagaaaataa tcatgccggg tctaataaat tcacatatgc atatatacag ctcatttgct
    23041 agaggaatgg cagttccagg aaaaccttct gagaactttt tagagatact aaataattta
    23101 tggtggagac ttgacaaaca gcttacactg gaagatacaa aatacagtgc atatgcaacg
    23161 tatatagaat gtataaaaaa tggtgtaaca acagtttatg accatcatgc aagtccaaat
    23221 gcaattgaag gcagtttgtt tacaatatca gatgttgcaa aggatttggg aattagaacg
    23281 tgtctttgtt atgaagtgtc tgatagagat ggtggaaata caatccaaca aggtatcaat
    23341 gaaaacgtaa actttataaa atacgctcaa aaagatgata cagacatgat aaaaggaatg
    23401 tttgggcttc atgctgcatt tacactatct gatgatacat taaataaatg tgcttcagag
    23461 atggctggtc ttgatacagg ttaccatgta catgttgctg aaggactagc agacttacaa
    23521 tataatgtag ataaatatgg aaaaagggtt ttagaaagat tcaatgattt tggagtacta
    23581 aaagaaaaaa caatagcagt tcattgtata tatataagtg cagaagaaat cagtctttta
    23641 aataaaacaa atacatttgt agttcataat ccagaatcta atatgggaaa tgcagttgga
    23701 tgttctcctg caatagagtt attaaaaagg ggagttacag taggattagg aactgatgga
    23761 tatactagcg atatgtttga atcattaaaa gttgccaata taattcacaa acatcactta
    23821 aaagacccaa gagttggatt tgaagaatca caaacaatgt tatttgataa caatagaaaa
    23881 atagctaaag cttattataa aaatgaccta ggagtactta aaaaaggtgc ttatgcagat
    23941 gttatagtag ttgattatat accacatact ccattgacag aaaatacaat agggggacac
    24001 actatttttg gaatgagtgg aagaagcgta gatacaacta ttataaatgg aaaggtactt
    24061 atgaaagata gaaagttaat aaacatagat gaagaaagta ttttagcaaa aagtagagaa
    24121 ttaagtcaaa atctatggaa tagaatttaa ataattgata ttaatataca agtaagaaac
    24181 aagaatttag atgttaaaaa cagagcttaa acaaaaatag gaatttaaat gaagtatata
    24241 aataaaaaat atacggaata gaatattaaa ttaaatatag aagggagacc caaaatgtct
    24301 cgagataaaa gccctaaaat agctccagta gatgaaaggt tacctgtatc caaatcttgg
    24361 gtattttcac tacagcacgt tttagcaatg tgtgcaggag cagtagcagt tcctatgatg
    24421 ataggaagtg ctgcacgact agatcatgct agtattgttt ttttaataaa tgcttgcttg
    24481 tttatggcag gtataggaac actcatacaa agtgttggta taggaaatat tgtaggtgct
    24541 aaaataccag taatagaagg aactagtttt gccgctgtgg caggtatgac agcaatagcc
    24601 tcatcatata gtgattcaca agttgcaata cagacagtat ttggctctgt aatagtagct
    24661 ggattgtttt gtatattact tgctccagta tttgaaaaat taataagatt tttccctagt
    24721 gtggttactg gaacagttgt tatggtaata ggtatttcac tatttccagt tgggataaaa
    24781 tggataactg acaacaaatt ggaagcggtt gaaccaaact cattagcatt agctttagca
    24841 gtattggcaa taactttact ttcatttaaa ttcttaaaag gaatttggaa tagtacagct
    24901 atattggtag gtatagtact tggtacacta ctttccatgg cagttggaat ggcagatttt
    24961 agtgcagtaa atggagttgg ttggcttaac ttaaatgtac ctttaaaatt tggaatgcct
    25021 agatttgaac catctgcaat actatcattg tgtttgatta tgttggtact tatgacggaa
    25081 tcagttggta atatgatagc tattcatgaa atggtagaca aagaagtaac aggtaaaaat
    25141 attaaaagag gtctatttgg agatggaata tctacagcat tatctggaat attcaattca
    25201 tttccaataa ctccatttgg tcaaaataca ggaatagtag gtcttacagg tataaaatca
    25261 agatttatag cagtttacgc aggggttata ttgctagtac ttggattctt accaaaattt
    25321 gcagcaataa taggagcaat acctaagcct gttcttggag gcgtaggatt tgcaatgttt
    25381 ggaatggtaa tggttggagg agtaaaaact ttaagcaaag tgaaatttga tggaactaaa
    25441 aatggggtta tagtagcagt tagtgttggt ttgtctatga taccactaac aaatcctgat
    25501 ttctatcata atttcccaac ttgggtacaa acaatattcc atagtggaat aacaacaggt
    25561 agtttatcag cagtgctttt aaacatattc ttcaatgaac taggttctaa aaaagaaaaa
    25621 aataataaag ttgaagaagc aaaataaaaa taaaacaagt aaaaatctat attgacttaa
    25681 agtcattaag cattaataaa aataattcag agatattaat aattcaacaa aactatctta
    25741 tattttaaat aatataaaaa agtaaataaa taacgaatac aaataaaaga atacaatcta
    25801 aatattaaaa atatttaatt taagggagag ataataatat ggctaattta aaagttaatt
    25861 tatatggaat ggaattttta aacccaatta tgacagcggc aggacctgga gcaaaagatg
    25921 gtgctctctg tcaagaggca gcaaaaggtg gagcaggagc tatatgtaca aaaactatat
    25981 ctgtattacc agctgatgta ccaagaccat gtatggcaaa aactaatagt ggttttttaa
    26041 acacagaatt atggtcagag cttccaaaag agcaatggat agaggaagaa tacaaaaagg
    26101 taaaagaaac agggcttcca gtaatagtaa gtatgggata ttcagcagag caaatagctg
    26161 aggttgctcc tttagtaaag ccttatgcag atgcagttga attatctact cattatgtag
    26221 gtacagacgt tgcaccaata gtaaatgctt taaaagctgc aaaagctgtt ttagatgtac
    26281 cagtatttat gaaaatgagt cctcatactg acattcaaac tattgcaaaa gctgttgaag
    26341 aagcaggtgc agatggactt gtaatgataa actcatttgg accatgtatg gcaatagatg
    26401 taaatacagg ataccctata atgggaagta aagctggata cggatggtta tcaggtgcac
    26461 caataagacc tctagcaata agatgtatat atgaagcttc tcaagttgta aatataccaa
    26521 taatcggtgt tggtggaatc acttgtggaa aagacgtggc tgaaatgatg atggctggag
    26581 caagtgctgt tcaagtatgt acagaagcaa tccttaaagg gccttctatc tatggaaaaa
    26641 ttgctaaaga attaaatgaa tttttagatg agaatggata tgctgatgtt aatgaaataa
    26701 aaggattaac tcataagaaa atggcagcta gagggtttag aactcattca gtagctccag
    26761 tagtggatga taacaagtgt atcaaatgta agcaatgtgt aacaagctgt gtatacgaag
    26821 ctttagaagt tacagataag ttgaacatag atgcagacaa gtgttttgga tgtggattat
    26881 gtgtaactag atgtccaaaa ggagctttaa gcatctgcta caatcaagta gaagctatga
    26941 atgagtaata attatataga attttggtaa ttaacttaga gtaataggta ttaggataat
    27001 aaaatatatc agataaacaa acacgcatta tgcattaata atacagtcta aagttaataa
    27061 ttttattata ttgatttaac taaatattag tttagctgaa tattaattta attaggtatt
    27121 ggtttaatct taatatagat ttactacgta taagtgaact aactagatta ctttaagtta
    27181 attttttcat ataaaataaa ttgatacatt acaagtaagg tggagtctat atgggaattg
    27241 ttttaaaagg tgggaaagta gtaacaagtg aaaaaactta ctgtgcagat gtaagaatag
    27301 aagatgaaaa aatagtcgat ataggtcttg atatatcaaa agaaaatgat gaaatagttg
    27361 atgttagtga ttcttatgtt ataccaggag gtatagatac acacacacac tttgacttag
    27421 atacaggcgt tactaagaca gcagataact ttgagacagg aacaaaagct gctatagtag
    27481 gaggaactac tactatattg gattttgcta cacaagctaa aggatgttct ttgaaagacg
    27541 gattagaaga atggcatgaa aaagctaagg ataaatcata ttcagattat ggctttcata
    27601 tggctataac agattggaat gactcggttt gtaatgaaat ggaggatatg gtgaaagagg
    27661 gagtatcttc atttaaactg tatatggcgt ataaaggaag ccttcaagtt gatgatggtg
    27721 taatctttga agcattgaga aaagcagaag agataggagg gattattggt ttccattgtg
    27781 aaaatgggga cataatatgt gaacttgtgg ataaagcaaa gtcagaaaat aatttatctc
    27841 caaaatatca tcaattaact agaccagcta taatggaggc agaagctaca tcaagactta
    27901 tgaagatagc tgaagttgca aactctaaag tatatgtagt tcacttaagc tgtaaagaat
    27961 ccttagagga ggttttaaaa gctaagcaaa gaggtgtgga tgtaatagtt gaaacttgtc
    28021 ctcaatacct tctattaaat gatgaattat atgatttaga tggatttgaa agtgctaagt
    28081 atgtaatgtc accaccttta agaaataaag aaaataatga aatattatgg aatgctattt
    28141 tagataatca aatagacact ataggaacag accattgttc ttttaattat aagggacaga
    28201 aggaacttgg gataaacgat ttcagtaaga taccaaatgg ttctccaggt gtagaacata
    28261 ggatgagtct tttatacaca tatggagtct gtaaaaataa aatatctatc aacaagatgg
    28321 tagaagtaac atcaactaat gcagcaaagt tgtttggaat gtatcctaat aaaggaacta
    28381 tagaaatagg cagtgatgca gatatattag tcttaaatcc aaacaaaaaa tccaaaatag
    28441 aagcaaaaaa acaattacaa aatgtagatt atacacctta tgaagggtat gaagtggatt
    28501 gtcaaataga acatgtttat ttaagaggaa aagaagtagt tagagatgga gaattaattt
    28561 gtaatactcc aagtgggaga tatataaata ggcgtctaac aaagggggct agagaatggt
    28621 agaatttata ttaaatggag agaaagttgt tgcaaaagaa ggcaaaaaac ttttagactt
    28681 ccttagagaa gatatgaata taacttcagt taaaaatgga tgttcagaag gtgcttgtgg
    28741 aacatgtatg gttataatag atggtaaagc tactaaagca tgtgtattta aaactgataa
    28801 attagctggg aaaaacataa caactataga gggattatca gagagagaaa gagatgtttt
    28861 tgcatattct tttgctagtc aaggagctgt acaatgtgga ttttgtattc caggtatggt
    28921 aattagttca aaagcactta tagacgttaa taataatcct actgaagatg atataaagaa
    28981 agctttaaaa ggtaatatat gtagatgtac agggtatgta aaaataatta aagctgtcga
    29041 tttagcagca aagattttta gagaaaatat agatgtgcca aaagtaaact gtaaaggtct
    29101 agtaggtgaa aatcttccta gagttgatgc agttggcaaa gcacttggat attctgaata
    29161 tgtagatgat atgagaattg aaggtatgat ttatggttca gcagttagag ctaagtatcc
    29221 tagagcttta gttaaaaaaa tagatataga agaagcaaaa gcttatccag gagttgttgc
    29281 agttctaaca gctaaagata ttccaggaac tataaaggta gggcacttaa agaaggattg
    29341 ggatacttta ataccagaag gtgaaataac tagatactta ggagatggaa tagttttagt
    29401 agcagcagaa actagagaag cgttagaaga ggcaaaaaag ctagttaaga tagattatga
    29461 ggaattaaca ccattaagta ctacagaaga tgcgcttaga gaagatgctc caaagataca
    29521 cgagacaggt aatatacttg ttaaggaaca tttagtaaga ggaaacgcta aagaaaagat
    29581 agaaaattca aaatatgttg taactaaaag atatactaca cctgctacag aacacgcatt
    29641 tttagagcct gaatgtgcag tagctggtcc ttatgaagag gatggagtaa taatctattc
    29701 aacagaccaa ggggtgtttg ccactcaaca tgaatgtgca gatatgttag ggctaccata
    29761 tgagaaggta agagttataa acaaaatggt aggaggagga tttggtggaa aagaagacat
    29821 gagtgttcaa caccatgcag ccttacttgc ataccatact aagagatttg taaaagtaca
    29881 gttaacaaga aaagaaagta ttattgttca tccaaaacga catgccacag aaatggaatt
    29941 tacgacagca tgtgatgaaa atggatactt aacaggtatg aaggcaacga taatatctga
    30001 cacaggtgca tatgcctctc ttggaggacc agtgctacaa agactgtgta ctcatgcagc
    30061 aggaccatat aattatcaag atattgatat aacaggaaca gcagtatata ctaataaccc
    30121 tcctggagga gcatttagag gatttggagt tacacagagt tgttttgcaa ctgaatgtaa
    30181 tctaaattta cttgctgaaa tggttggaat atctccttgg gagataagat ataaaaatgc
    30241 aataagacct gggcaagttt taccaaatgg tcaatttgca gatgaaggaa cagcaatggc
    30301 agagacacta gaagctgtaa aagaagagta tgaaaagcat ccacgtgcag gtatagcttg
    30361 tgctatgaaa aatagtgggg ttggagttgg tatacctgat gttggaagat gtagattggt
    30421 gataaaagat ggcaaagtcc acataagaac aagcgcttct tgtataggtc aagggcttgg
    30481 tactgttatg actcaagtag tttgtgaaac tgctagccta cttcctgaaa atgtagtgca
    30541 tgaagttcca gatactcatt taacaccaga ctctggtaat actacggctt caagacagac
    30601 agtatttacg ggagaagcta ctaaggttgc gtcaaataag ttaaaagaag ctttagactc
    30661 tggcaaaact ttacttgatt tagagggaga agagttttat ggagaatatg aaagtattac
    30721 agataaaatg ggttgtgaca aagaaaatcc agtaagtcat gttgcttatg gatatgcaac
    30781 acaagttgta attctggatg aaaatggaaa attggaaaaa gtagtagcag cacatgatgt
    30841 tggaagagct ataaatccaa tcagtttaga gggtcaaata gaaggtggag tagttatggg
    30901 tcttggatat gctctaaccg aagattaccc agtagttaac tctgttccta cagctaagtt
    30961 tggtacatta ggtttattta aatctacaga tataccagaa atacaagctt taatagttga
    31021 aaagaacaaa gatttattgg cttatggggc aaaaggtgta ggagaaattt gtacagttcc
    31081 tactgcacca gcagtacaaa atgcctatta tgtatttgat aaagaattta gaactgaact
    31141 accactacaa aatactccat atagtaaaaa aaagtaacaa aaaaaagaaa tattaaataa
    31201 aaaaatagat gaaattgtaa ataaaaaaat agatgaaatt gtaaataaaa aaatagatga
    31261 aattgtaaat aaaaaaatag atgaaattgt aaataaaaaa atagatgaaa ttgtaaataa
    31321 aaaaaaccct tttgcataag gtatatttta aatgatagaa tatacatata caggagggtt
    31381 tttcttttat aaaataagtt taataaaatt gagaggtgag cagaatgaat tttaataata
    31441 gtctagaatt aactcagtct cagaagctaa taatgactac acaacttaag caatcattat
    31501 caatattaaa tatgagtaag ttagagttag aagaagagat aaaaagagaa gcagagaata
    31561 acccattagt tgaagtcgag aaaagtgggg agataaattg ggaagagtat ataaaagaca
    31621 tggataggtc aagacgttta gatagaacag agataagcta taatcctgat aatgaagtta
    31681 atctagaaaa tttagttaaa tattcgtcaa atttatatga agatttaaaa tttcagataa
    31741 gcctgtataa acttacagac aaagaattgg aagtctgtga gtatataatt gatagtttag
    31801 atgaggatgg atatttaaga actgaggaaa aagtaattgt tgatacctta aagatagatg
    31861 aagaactttt tgaaaaatgt ttaattagtg ttcagcagtt ggaacctagt ggagtagggg
    31921 caagaagtct ttcagaatgt ctgatgatac aaatggctag tttaggaata tataatgaaa
    31981 ttttagagga aatcgttaca aaagacttaa atttaattgc aaataataaa tacaaagaga
    32041 taagtaaaaa gtacaatatg tcattacaaa aatgtgttga actaataaac ataattaaga
    32101 cattagaccc aaaaccagga agaacttgtt cagtagagaa aagtgtatac attcaacctg
    32161 atgtaacagt agaaaaaatt gatgatgaat ttattgtata tttaaatgaa aaagattctt
    32221 atcaaataag aatcaatagt tattataaag acatattaaa aaattcacag tctgatgaaa
    32281 gtgcaaaaga atttataaaa gaaagactaa attcagcaac aggacttatg aaaaatatag
    32341 agagtaggaa aactacagta cttaagattg cagaagagat agtaaaagct caagatgaat
    32401 ttttgagaaa agggacaaaa tatataaaac ctttgaaaat gaaagacata gcagaaaaat
    32461 tagaatttca tgaatctact ataagtagag gtgtaaatgg taaatatatg ttaacacctt
    32521 ttggtgtata tgaatttaga tactttttca gtagtgccat tgagactgag aataatgaaa
    32581 tggcatctag tacaagcata aaaaaaatta taaaggaaac aataaaagac gaaaataaaa
    32641 agaaaccttt aagtgatgac catatatcta agttactaaa agaaaaagga atcaatgttg
    32701 caagaagaac agttgccaaa tatcgtgaag aattaggaat cccatcttca agtaagagaa
    32761 aagaatacta ataagtaaaa gacaaatatc agtatggtaa ggggaaaagg ctaattaaaa
    32821 gatgaatgta gattgggcta aaaattttat gaagtaaaat aatagaatat ggaaaagtat
    32881 taaaatgcta taagatatta aaaaactggg gaacattaaa acattaagat agcaaagaac
    32941 ataaaaaact aaagaagatt aaaacattaa agaacattag agctttgagg aatattagaa
    33001 ctttaaagaa tattaaaatt tataaaatat aaaaatacta aaaagaattg aaaaactggg
    33061 gaacattaaa atattgtaaa atgctaaaaa actagaaaac ataattaaat aagtgcttat
    33121 aaagaatgat taaattaaat aagtgtttgt aaagaataat tagatattag aaaaagaaga
    33181 atacctagat aaataaacta ttattaaatt taataatcat aaaaggaaaa cacagggtat
    33241 aaataaaaat cttaactaga taaaagtaaa cttagttgta gataaaaata actagaaata
    33301 aaagtaacta gaaataaaat tatttatagt aataaatatt agaatgaaaa tataaaaaaa
    33361 tatatataaa aagccttata taaaaagaaa aaatactgtg atttgaaaat ggtggagaaa
    33421 tattttataa aataaaaaaa taaaaaagtt tttgaaaaac tattgaaatc tatacgcaaa
    33481 tcctataaaa taaaaatatc ttgtgggact taaataaaca ctagggacga aaaaagtccc
    33541 gaaaggaaag caataaggag tatgttatga agaacttatt agaaattcaa aagaaattga
    33601 ttccacaggc aattgaactt atggaaagaa gatactctat tttaagacaa atatctttaa
    33661 gtgaaccaat aggtaggaga acattatcaa atgtattaga gattagtgaa agaataatca
    33721 ggtcagaaac tgagttttta aaagaacaag gacttataga cgtagctgta tccgggatga
    33781 ctatcactaa agaaggttct gatttgttag ataaacttaa ggacatcatg agtgacatca
    33841 tgggattgtc taagttacaa gatagagtca gagaaaagct tggaataaaa agggtaatat
    33901 tagttcctgg aagctgtgat gaaaatggaa gtttactaaa agatgtaact agatatggat
    33961 gcgagtattt cttaggtatt ttaaaagatg gagatatcgt ttcaataaca ggaggaagca
    34021 ctatgttgga gttttcaaac gttattaaaa ctgataagag atacccaaac tctacaatag
    34081 ttccagctag aggaagtatg ggaactgatg tagagatgca atctaataat atagttgctt
    34141 cgataagtaa gaaattacat tctaattgca aacttttaca tataccagat gagttggatg
    34201 aaagtgcaat gaaaactctt agccaagtgc cagagattaa gacaactttg gagtatatta
    34261 aaagaacaga cattttagtt tttagtatag gtagagcaga tgtcatggca aagagaagaa
    34321 aacttccaga agacaaggtt gatgagatat tatctaaaaa tgcagttgga gaagcatttg
    34381 gatattattt caacaaagat ggagaaatag tttacaaact gaacactgtt ggaattgatt
    34441 tagaaacagt taaacaagta aaagaaacta ttgcaatctt tgcaggtact gaaaaagtag
    34501 aagccttatt agctatatca aatatgcata aaaacatggt tcttgtaaca gatgaagaaa
    34561 gtgcttataa gatattgtca ttattataaa agtcaagacc tagcacagag ctagaaaaca
    34621 tacatttact ttataggagg tagcgaaaat ggttaaagta gctataaatg gatttggaag
    34681 aataggaaga ttagcattaa gaaaaatgat ggagcaacaa gataagttcg aagttgttgc
    34741 aataaacgac ttaacagacg ctaaaatgtt agctcattta tttaaatatg atacagctca
    34801 aggaagattt aacggagaaa tagaagttaa agaaggtgct tttgtagtaa acggaaaaga
    34861 aataaaagta acagcagaaa gaaatcctgc tgacctacca tgggctgaat taggagtaga
    34921 tatagtatta gaatgtacag gattctttac atctaaagat aaagctgaag ctcatataca
    34981 agcaggggct aagaaagttg ttatatctgc accagctact ggagatttaa aaacaatagt
    35041 attcaacaca aacagtgata tattagatgg ttctgaaaca gttatatcag gagcttcttg
    35101 tactactaac tgtttagctc caatggctaa agtattaaat gataaatacg gtatagaaaa
    35161 aggattaatg actactatac atgcatacac taatgaccaa aatactttag atggtcctca
    35221 tccaaaaggt gatttaagaa gagctagagc tgctgctgga aacatagttc caaacactac
    35281 aggagctgca aaagcaatag gcttagtaat accttcatta aaaggaaaat tagatggggc
    35341 agcacaaaga gtaccagttg taactggttc aataactgaa ttagtttgta cattaggaaa
    35401 aaatgttaca gttgaagaaa taaatgcagc tatgaaagaa gcttcaaacg aatctttcgg
    35461 atatactgaa gaaatgttag tatcttctga cataatcgga ataagctatg gttcattatt
    35521 tgacgctact caaacaaaag ttatggaagt agatggaaaa caattagtta aagttgtttc
    35581 ttggtatgat aatgaaatgt cttatacttc tcaattaata agaactttag gatactttgc
    35641 acaattagca aaatagtcag ttttgagaaa atagaaaagt agattgacaa agtccgagtt
    35701 tgtagtttaa tactacggac tcaggacttt ttttaagaaa aaatatataa aatacaccta
    35761 aataatgtta catactatat ataaaaatat gataatatga tatatttaat agggtaaaag
    35821 tatgtactat attatacttg gcaataaaaa attactttat taaaaggaga gatatttatg
    35881 tcaatgctta acaaaaaaac tatagaagat attgatgtgt gcggaaaaaa agtattagta
    35941 agatgtgact ttaatgtgcc attacaagat ggtgtaatta ctgatgaaaa tagattgaac
    36001 ggagctttac caactattca atatttaatt tctaaaggtg cgaaagttat attatgctct
    36061 cacttaggaa agccaaaagg agaagctaag ccagaattat ctttagcacc agtagcaaag
    36121 agattatctg agatgttagg aaaagaagtt gtatttgcag cagacgataa tgttgtagga
    36181 gaaaatgcaa agaaagcaac tgaaaaaatg gaaaacggag atgtagtatt attagaaaat
    36241 actagatata gaaaagaaga aactaaaaac gaagagaatt tctctaaaga attagcatca
    36301 cttgctgaaa tatttgtaaa tgatgcgttt ggaactgctc atagagcaca ttgctcaaca
    36361 gttggtgcag gtgagttctt acaagagaga gtttgtggat acttaattca aaaagaatta
    36421 aaattcttag gagaagctgt tgcaaaccct gtaagaccat ttacagctat acttggagga
    36481 gctaaagttt ctgataaatt agctgttata aacgaattat tagaaaaagt tgataatcta
    36541 ataataggtg gaggaatggc ttatacattc ttaaaagctc agggttatga agtaggaact
    36601 tctttacttg aaatagataa agttgaatat gctaaagaaa tgatggaaaa agctaagaat
    36661 aagggtgtta acttattatt accagtagac gttgttatgg cagaccactt tgcaccagat
    36721 gctactccaa tagtaacaga agatgctaat gtaaaagaag attacatggg actagatatg
    36781 ggacctaaga ctatagcaaa ctttgtaaaa actataaaag aatcaaaaac tgtagtatgg
    36841 aatgggccaa tgggagtatt tgaatttgaa aactttgcaa atggtacatt atcagtagct
    36901 agagctatgg cagagttgac tgatgcaact actgtaattg gcggtggaga tagtgcagca
    36961 gcagttaatc aattaggatt tggtgacaag atgactcacg tatcaacagg tggaggagca
    37021 tcactagaat ttttagaagg taaagaatta ccaggtattg cagcattaga taataaataa
    37081 actaatatat agaggagatt gtaaaatgag aaaacctata attgcaggaa actggaaaat
    37141 gcataaaaca ataaaagaag ctttagaatt tgtaaatgaa gttaaagata aagtaaattc
    37201 tgataaagta gaagctgtta tatgtgcacc atttacttta ttaaaggatt taaaagaagc
    37261 tactaagggt acaaatataa agataggtgc tcaaaatatg cactttgaag aaaaaggagc
    37321 atttacagga gaagtttcac ctcttatgtt aaaagaaata gatatggact atgttgtaat
    37381 aggacattca gaaagaagac aatacttcaa tgaaactgat gaaactgtaa acaagaaagt
    37441 tttaaaagca ttagaagtag gaatagaccc aatattatgt gttggagaaa ctttagaaca
    37501 aagagaagct ggaaaaacta aagatgtttg taaagttcaa gttgaaaaag ctttagaaaa
    37561 tgttcttaaa gatgatttag caaaagtagt tgttgcatat gagccaatct gggctattgg
    37621 aactggtaaa actgcaactg ctgaagatgc taatgacgtt atatcttata taagagaagt
    37681 tataaaagga ttatatggag aattagctaa tgaagttaga atacaatacg gtggaagtgt
    37741 taaaccttca aatgtagccg aaataatggg tcaaagtgat atagatggag ctttagtagg
    37801 tggagctagt ttagctagta atgattacct agaccttgtt aatttctaag gagtgaaatg
    37861 atgaaaaaac cagttgcttt aattattatg gacgggtttg gatacaataa ggatgttaag
    37921 ggaaatgcaa ttgctgagtc caaaactcct aatttagata gaataaaaaa agagtatcca
    37981 aacacattga taaatgctag tggtcttgat gttggtctac ctgatggtca aatgggaaat
    38041 tcagaagttg gacacactaa cataggtgca ggtagaatag tatatcaaga tttaactaga
    38101 ataacaaaat ctataaaaga tggtgacttt tttactaata aagttttatg tgaagcaatg
    38161 gataatgcaa aagaaaattc tcttcatgta atgggacttt tgtctgatgg aggagtacat
    38221 tcacatatag accatcttaa ggctataatc aaaatggcaa aagataaagg cgtacaaaag
    38281 gtgtatgttc acgcatttac tgatggtaga gatactgacc ctcaaagtgc attagaatat
    38341 gccaaagaag tacaagctag tatggatgaa attggagtag gtgaatttgc tacagtttct
    38401 ggtagatact acgctatgga tagagataag agatgggaaa gagtagaact tgcatacaat
    38461 gccatggtta gaggtattgg tgaaaaagca aattctattg aggaagctat tcaaaactct
    38521 tatgatgatg gaaaaaatga tgagtttata atgccaacag ttattatgaa agatgataaa
    38581 ccagttggaa gtataaagga aaatgattca attatattct tcaactttag accagataga
    38641 gctagacaaa taactagagc tttagtttgt gaagagtttg atggatttaa aagagaagat
    38701 attaaaaact tctttgtatg cttaacagag tacgatataa ctatagagaa tgtgcatata
    38761 gcatttggac ctcaatcttt agccaacact ctaggtgagt atctagctaa aaatggaaaa
    38821 actcaactta gagctgctga aactgaaaag tatgcacatg taactttctt cttcaatggt
    38881 ggagtagaag agccaaataa aggtgaagaa agactattga taccttctcc aaaggttgca
    38941 acttatgatt taaaaccaga aatgtcagca tatgaattga cagataaagc tttagataaa
    39001 ttaggagaag ataagtttga ctttatagta ttaaactttg caaatcctga tatggtaggt
    39061 catacaggaa gtatagaagc ggctataaag gctgttgaaa ctgtagatac ttgtgtagga
    39121 agattgatag ataaaatagt agagttaggt ggaagtgcaa taataactgc tgaccacgga
    39181 aatgctgaat atatgttaga cccagaaaca ggaaaaactg taacggctca ctctattaat
    39241 ccagtaccat ttattgtagt tggtcaagaa tatgaaagtg caaaattatt ggatggagga
    39301 agattatctg atatagcacc gactgtttta gatatgatga agttagaaaa gccagaagaa
    39361 atgactggtc attcacttat ttcaaaatag tcgattctga taagtagaga ataatatata
    39421 aactacaata taaatttaaa aataatgcag tttaggttta ttttgtaaag tttagacttt
    39481 atgacagaag atttagattt tgtaagtttt ggatattgta aggtgtagat gaagatatat
    39541 tttataaaat ttacaagata gacaatttat aaaataaaaa attataatat agataataat
    39601 gtaaataatg atataaataa taacaagata gacaataaca atataaataa taataattaa
    39661 tatatattat ataagcaaaa attttagaat cattagttgt acattttatg tttaatgttt
    39721 taaatctagt tataatattt gtgtatttaa gattggtttt ggattttaga caagtttttt
    39781 tatattatat aaattaaaat attataaaaa ataaaataaa aataggaact tttacaaatt
    39841 tacccatcaa ataaatttgt acctaatttt caaaagcaac tttatgtact ataatataga
    39901 aagtagatta aaatagtaga cggatgttta cagtaaatga aaatttaact aatagaaaat
    39961 cgaagggaga tatacaaatg tcagttattg aattagtata tgctagagaa gtattagact
    40021 caagaggaaa tccaactgta gaagttgaag tagtattaga agatggagca atgggaagag
    40081 caatagttcc atcaggagca tctacaggag cttttgaagc tgttgaatta agagatggag
    40141 ataagggaag atacttagga aaaggtgtag aaacagctgt tgctaacgta aatgaaataa
    40201 tagcacctga aatagaagga atggatgcat ttgaccaacc agctatagat gcaatcatga
    40261 tagaattaga tggaactcca aacaaaggta aattaggagc taatgctata ttaggtgttt
    40321 caatggcagt agctagagca gctgctgatg aaataggttt accattattc caatacctag
    40381 gtggagtaaa tgctaaacaa ttacctgttc caatgatgaa catattaaac ggtggagagc
    40441 atgctgataa caacgttgat gttcaagaat ttatgatatt accagtagga gcttgttgtt
    40501 tcaaagaagg tttaagaatg ggagcagaag tattccattc gttaaagaaa gttttaggag
    40561 aaaaaggatt agcttgtggt gtaggtgacg aaggtggatt tgctccaaac ttaggttcaa
    40621 acagagaagc tttagaatta atagttgaag ctataacaaa agctggatat aagccaggtg
    40681 aagacgttat gttaggtctt gacgttgctg ctacagaaat gtacaacaaa gaaactaaaa
    40741 aatacgtttt agcaggagaa ggaaaagagt taactgctgc tgaaatggtt gctttatatg
    40801 aagattggtc aaacaacttc ccaataataa ctatagaaga tggtttagac gaagaagatt
    40861 gggatggatg gaaattatta actgaaaaat taggaaataa attacaatta gttggtgacg
    40921 acttatttgt tactaacaca gagagattag aaaaaggaat tgaaaatgga gtagctaact
    40981 ctatattagt taaagttaat caaataggta caataactga aactttagat gctatagaaa
    41041 tggctaagag agcaggatat actgctgtta tatctcacag atcaggagaa actgaagatt
    41101 ctactatagc agatttagct gttgcagtaa atgctggtca aataaaaact ggtgctccat
    41161 caagaactga tagagttgct aagtacaacc aattattaag aatagaagaa atggttggag
    41221 agcaagctag atattgtgga ttaaaatctt tctataactt aaaaaaatag ttattaaaat
    41281 ggttactaaa aaagattaat gaagagagaa tataagatat ttaagctcat cttataagat
    41341 ataaaagaga taagtgttaa ttgatttttc aattcactta tcctttttta tattttatta
    41401 cttaatttta ttcatagatt cagaaaaaat atgaataaat gtttctatct catttttatc
    41461 taattgcata ggaggttttt attaaaaaat aaaagtgaag acatattttg atttaatcat
    41521 aattgtcatt aaagtattat tgctaaatgt ggattattta ttttaaatta tgttgaaatt
    41581 aaaagttata tcaatatttt aaaatgattg ttttattttg gtggctattt ataatatata
    41641 caatgagagt agattatttt aagtgttaat ttatgcatta atttaaatag ttttctcttc
    41701 taagttttat tcatttttat attgagaata tagtaatata ttatagtaac aatatatttt
    41761 tttgtatgtt atttatagca taatagtctt gaaatggcta tattattgtg atacactaaa
    41821 gagtaatgaa atttaagtaa taaacagata ggaggggcaa gaatgagcaa cattttaatg
    41881 ggtgtgcaag tagtactagg gattttacta gtaattagca taatgcctca agattctaag
    41941 aatgctttac cttcagaatt tggtggagaa ggaagccaag cttactttaa accaaaagga
    42001 aaacaagcat ttcttgctag agttacaaag ataacagcag tattattttt tataaatgca
    42061 ttggcattac ttatagttaa gaagtagtga tattgttgaa taactggcca ttatttaatt
    42121 agtgcatttg ctagacattt aaaaattaaa tttagttttt aataaaagta catcaacata
    42181 aaaagtacgt aaaataaaag ctggactaat gattttatat gattagtcca gtttttattt
    42241 tatagattga ctatttgttg gcgtttatta tttgtattta tatattgttt gtatttatat
    42301 atttttttca aactaaaaaa tatatagcaa cactactttc accatgttta atgagataat
    42361 atacacaaag ttatattata tagtaaaaat agtataataa tatgttttta cgcaattaaa
    42421 tcgattttat atatgtttct cataatacca atttgtgtta tcaaatatca ttaaataaga
    42481 ttattctgct ttaaaataaa tattattaaa aatactgtaa ttatagaaaa tccagaagta
    42541 aatactacaa tttgtccagc taattcactg tcagaatcca tctgttgtgc cattgtaaat
    42601 gaagaaactg cagttggagc agataacatt atcataagtg aagctaattc tacatttcta
    42661 aatccaagaa aaatgctaat tggtaaaaat atagcaggta caagtataag ttttccacat
    42721 acgcccaata taatggggtt tatatgcccc tttatagcag aaaaactaaa agagccacct
    42781 agaattataa gtgataaagg agtagctatt ttagaaatat caccaatagt tttgtgtaaa
    42841 aatgtaggta tattaatatt taaaattagc attgtcaatc ctataaaaga ggcgattatg
    42901 agtggatttg ttaagacgct tttaatcata tgttttatat ttactttgcc acctctaaaa
    42961 atttcaagaa ttacaacaga taatacatta aacataggta caataactgc aattaataaa
    43021 gatgtgactc caatactctt atcgccaaat agtgaaattg tcacaggaat accaaatata
    43081 acgaaattgc tacgaaatac accttgtatt aatgcacccc ttgtcttatt atctttttca
    43141 attttaggaa taataaagac taagattaag aagattgaaa aaataattat aacagctaca
    43201 gccataagcc taaaattaag agaaccatct aaatctgtat tgtatatatt aaaaaataat
    43261 aataatggca agaaagactt gaagcagaca ttattcattt tatttaaagt atgagtatca
    43321 aatagaccta atttttttag aacatatcca agtgacattg tgagaaacaa aggaagaaca
    43381 acatttattg ataggattaa attttccaag gtttactctc cgtgattcta tgatttgata
    43441 attcaattaa atttccatta gtttttttca aataaataga tttcatatta ccaaagacac
    43501 ctgtacattc tacaattcct cgcttaattt gaatctcatt ttgttctaag tatttttttg
    43561 gctcatcaat atttgtgttt attttaaaac ataagttatc tctacttgct tgtaaatttt
    43621 taacataagg taaaaattta taacctttta tgttaagatt tatcttaata tttctagcat
    43681 taagtttata atttttgctc atttctttag atgaaaaacc aaatttttta taaaaattga
    43741 tataattttc tatattatta ttagtaatga ccacatgttc tatttttttt atcatggcaa
    43801 ctccttaaga ttttatataa gttattaaat tttatataga ttgataatat ttatataa
//
LOCUS       DAEPKC010000022        41795 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.022, whole genome shotgun sequence.
ACCESSION   DAEPKC010000022 DAEPKC010000000
VERSION     DAEPKC010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 41795)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41795)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41795
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.022"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..2191
                     /locus_tag="KR294_001294"
     CDS             <1..2191
                     /locus_tag="KR294_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="sporulation-associated two-component system
                     sensor histidine kinase"
                     /protein_id="HBH0239377.1"
                     /translation="SGIELNSSSNKGKWEYDEKKIFNRIIVIIILSRVPNLLHIVIDN
                     RNVERILSQIIINVALYYLYNYIVSKNIKKTALELHDTNEELTKKTESLKEKNKKLIY
                     ETEKIEELKGILMKRESRLQSTLDVAVNSIVVFSKDGEITYANKSFRNTFGDYKEQDK
                     LTDKIKNFNDLIESIHYVFVHEKNAEKLISTSDNKVYQAIFAPLIIASQTEGVLCVLE
                     DKTKKKEYERKLIEANKRSKDFLESIGDGIVVLEGNNKIYVNNACREIFKNNLESIDF
                     SLVCKSEESIEKRYVIDGEVKYVEMSFSQYTNAGTNKTIIVIRDTTSRKISQIKLEES
                     QSSYSRFIDILPDGICLLKEDLSINYANKSFLDMLAFTNIDDIKDSNIKLLMNANTEE
                     KMKFTDNMAKVLNENRSILLLEYELINSYDDIVEVELSALPFAIYNTRYIMLIIKDLV
                     HKKYSEQAEKELLERFKTDKIKTEFFANMSHELKTPLNVISSSNQLVDSFYRNEKIKD
                     YNNNIKSHVDLVRQSSYRLQRLINNIIDLTKMESGFYTLKLAKYNIVSVIEDLFMNIE
                     EYALRKDIKILFDTDLEEINVYIDKVEIERIMLNLLSNCIKFTDNGGWIYVSIHYKID
                     KVIISVKDTGVGIPQDKLELIFEEFSQVDKTLSRNTEGSGIGLAIVKNLVSLHGGDIE
                     VVSEVNKGTEFLISLPMKGFSSEHYTEDKRIYNIQEKIKIEFSDIYY"
     gene            complement(2310..3254)
                     /gene="manA"
                     /locus_tag="KR294_001295"
     CDS             complement(2310..3254)
                     /gene="manA"
                     /locus_tag="KR294_001295"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HBH0239378.1"
                     /translation="MEPLFLKPIFMDRIWGGTALKDKFNYEIDSPTTGECWAISSHKN
                     GDCLIENGKYKGKKLSELWNKNRELFGNTPGDKFPLLTKILDANDNLSVQVHPNDEYA
                     KKNENGELGKTECWYVIDCSDDAEIIIGHNAKSHKEFVNMVNNNEWDKLLRKVNIKKG
                     DFFYVPSGTIHAICKGTLILETQQNSDTTYRVYDYDRTDNSGNKRELHVQKSIDVTNV
                     PHINFDTDYKIVSTSDFKCTTFVSNEFFSVYKLDVFGKCNFTHNTPFSLYSVLDGNGK
                     LIHNSVEYNLKKGMHFILPNDFGDFSFEGNLEIICSHI"
     gene            3427..4788
                     /locus_tag="KR294_001296"
     CDS             3427..4788
                     /locus_tag="KR294_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBH0239379.1"
                     /translation="MELFKAESKKYKKEFLKLLEQWVSIPSFYDRKTVSKDMPFGKGV
                     YDALNWFENLGRENNFKVKNIDNHAVQIEYGNGKEYVDIFGHCDVVNPGEGWDSEPFK
                     LNIIGDKLVARGVSDNKGPMIVNFLALKMIKDLDINLKRKVRLIAGGNEESGFKCIKH
                     YYSKEPYGVCGFTPDAKFPVLNGEKGGAIIKLISNIDDKSLYISGGIEFNTIPDKVYI
                     KNVEKLGKDNICFDINNISINYDNGNYIVYGKGGHSSKPEKSINPILATIKLLSENID
                     EKWTKDLYKLINQDNINGNLFGLNIEGKCGILSMVPTIINIVDGKLEVVLSVRYPEIL
                     TIEDIIKKFNLYMEQNNINKFELIGENLKQANYIDRNSKLVRSLHDIYIKYSGDLKND
                     VRVTSAGSYASEMNNSVIFGCEFPDGSFGNVHSANEFASLDRFITAIGIYAEAIITLC
                     NKI"
     gene            4876..6765
                     /locus_tag="KR294_001297"
     CDS             4876..6765
                     /locus_tag="KR294_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBH0239380.1"
                     /translation="MITKKHAIIVKSLSNKDGYMTSNELAIKLDVSTKTIKRYIADLN
                     SVLSKYDLVIASSRGIGYKLSGSKNNIARAVKEANKYIDGFLDDSEESRMSNIICMLI
                     NRNYMSIEAMAEELNLSIAAINKLSSKLKRKLEKYDLVIKSKPYYGSYIHGEEINIRQ
                     LITDYAIKLDEKSKVKVFLDDISENDIHCIESILEKHLREKDTIISDKDFNLLLSKII
                     VSVFRSKRGHSNNINLMDTSYRFHNYYFIENLMKEISDKIGFKLIEDEVIYISNYSGV
                     IAYKGTQGRKNTSEIEERISTVISSALQDIFLISGSDYTKDDEFMVAISDHIKRFLNR
                     ARANVKSNNPLLHQIKEKFPIAFNLAVFLSNKLETEFNLKLDEDELGYIAIHFAASNE
                     RMKKNTSKKICIVCHYGIGTGQLISEKLKQNISDLSVVGVYPVRYLDMAISQDVDLIV
                     STVELKGYEKPVLYIENIFDDSLIENVNKAFYEKEERRKIISNMFDEKAFFSIKASTK
                     EEVIISLSNKLKERDFIEESSIKSIIDRENISSTEIGNLVAIPHTIVKGDKKSIIGVG
                     ILENPIIWDKQEVQLVFMVFFNTKEKHNFSIFKYLYNFIKDEGGVRGIIKICDFNKLM
                     ALIGN"
     gene            6780..7235
                     /locus_tag="KR294_001298"
     CDS             6780..7235
                     /locus_tag="KR294_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH0239381.1"
                     /translation="MGTNIFNKEYVFLNVDAKSKVEVLKFISKKAKDLNLAEDESLVY
                     EGLMAREEQFTTNLGESIAIPHTKNDAIENPAVVVLKFNEDVVWNEGEDKVKLAISLL
                     MPGKSKENIHLKLLSSLSRKLINKEFKDSLLKSDNVEEISNLINEALGL"
     gene            7294..7611
                     /locus_tag="KR294_001299"
     CDS             7294..7611
                     /locus_tag="KR294_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HBH0239382.1"
                     /translation="MNKKLVALCACPMGLAHTFMAAEAIEQAAKALGYEAKVETQGAD
                     GVQNELTRDDILGATMIIHAVAITPEGMERFDGCEVYEVELQEAIKNAEGVIKEIEED
                     LGI"
     gene            7636..8898
                     /locus_tag="KR294_001300"
     CDS             7636..8898
                     /locus_tag="KR294_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HBH0239383.1"
                     /translation="MAIKKKVINSSGASTTGGNNVGKSTPSSPTQSKGNGKWKEISKH
                     IMTGISYMIPVLVMGGLIGALSQLIPYAILGLDPSVGIVDAMNSGEFTGFKLSLLNIA
                     QLMSNFGFTLFGFAIPLFAAFCANSIGGKTALIAGFIGGYIANKPVGVPQFVDGQWTE
                     VVPVASGFLGAILIAFIIGYFVKWLNKSIKVSHNWLAFKTTFLIPLIASLACMVLMIF
                     IITPFGGLINESMKNFLTAAGAAGEYVYATALAAATAFDLGGPINKAAGFVALGLTTE
                     NVLPITARTIAIVVPPIGLGLTTLLDKRLVGRRVYDRQFYQAGKTSIFLSFMGISEGA
                     IPFALERPGFVIPLNIVGSVIGAITGIILGAIQWFPESAIWAWPLVDNLFGYIIGIAV
                     GAIFIAVGNIFYRNKLIKDGKLVVDYID"
     gene            9003..10067
                     /locus_tag="KR294_001301"
     CDS             9003..10067
                     /locus_tag="KR294_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBH0239384.1"
                     /translation="MDKIEKVREYFREYDIDGFLINSPTNKFYVGNLFSSSGYVFITK
                     ESQYIIVDFRYFEEIKRKSSLFNVVLMDKTRTHFDIINDICREQNIKEIGFEGNEVSF
                     DLYRSMSNKLSATLKSVDLSTLRETKNEDEIKYIKKACEIVDATFYHIVDFIKVGMTE
                     KQVENEIVRIIKDLGGQKESFDTIVASGLRGALPHGKASEKVIEYGDFVTFDFGAKYN
                     NYCSDITRTICMGTINKELEEIYNIVRKANEECIRVLRPGMTTGEIDKVARDIIGSYG
                     YANNFGHNLGHGVGIMVHEYPALAPESNEVLKEGMIVTIEPGIYVPSLGGVRIEDDVL
                     ITQDGCMRLTTSTKDLIVVS"
     gene            10121..11299
                     /locus_tag="KR294_001302"
     CDS             10121..11299
                     /locus_tag="KR294_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PatB family C-S lyase"
                     /protein_id="HBH0239385.1"
                     /translation="MYNFDDKPDRVSEKCRKWDLNIIRDKFGDIREDFIPMWIADMDF
                     KIPTEIENKFIEAVRRGVFGYTYCYDEFYDSVIGWQKNMHEVNVEKEWITLTYGTVST
                     LHYVVQAFCKKGDSIILNTPVYDPFESSAKKQGVNVICNTLDVVNDRYYINFDKLEVQ
                     IKENKPKLMMFCTPHNPSGRIWTIEEMTRVATICKENNVILVADEVHAEHIHYGTFNS
                     ILKIGKELLENVILLTSPNKGFNLGGLKTSYSIVINKDIRDKFRNKLKQNSITSPNVF
                     GIIGLITAYNECHEWLSGVNEYIKSNYELLETWVNKYNKIKLMKMESSYLAWMDISGL
                     GISASEFTDKLAIDTGVLLEDGSHFVKDGEKYVRINLGTQKENVIEALNRMDLFLKSL
                     "
     gene            complement(11490..12548)
                     /locus_tag="KR294_001303"
     CDS             complement(11490..12548)
                     /locus_tag="KR294_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HBH0239386.1"
                     /translation="MNKKKITFIFVILILALILFSFFRSSSQNTKYSKTSYYLGTVNE
                     VTVFNVKESKSDKILNECDSILRYIDNKMSTHIPGSDVSKINDNAGKKFVRVSDDTFF
                     VVKEAIQYSKLSDGYFDITIGPLSNLWAIGTDKAKVPSDSKIQKLLPLIDYKNIILDE
                     KNKSIKLTKENMKIDLGAIAKGYAADKIVAYLKSEDVKKGLVNLGGNIFTLENGKNDK
                     PFKIGIQDPTSKNGESIGNIETTNKSVVTSGIYERFIEKDGKIYHHMLNPFTGYPFEN
                     NLSSVTIISDKSINCDALSTSTFGLGLEKGMNLINKIDNVDAIFITKDKKVYLTKGIK
                     DNFKLTDKSFSIEKLNKQ"
     gene            12615..12986
                     /locus_tag="KR294_001304"
     CDS             12615..12986
                     /locus_tag="KR294_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HBH0239387.1"
                     /translation="MKKKDILLILGILVVITACYGIINVINSKNAGNIEIYVDNKLYK
                     TVSINAKEEFKIESRGGYNIVKIHDKGVEIVDASCPDKVCVHTGFINKPSQSIVCIPN
                     RVSIKINTNEKNDNQEDIISK"
     gene            13023..13697
                     /locus_tag="KR294_001305"
     CDS             13023..13697
                     /locus_tag="KR294_001305"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HBH0239388.1"
                     /translation="MVNLGNDWDELLKEEFEKDYYLNLRKFLIEEYKTRQIFPNMHNI
                     YEALKHTSYKDTKVLILGQDPYHGDNQAHGLAFSVQPQVKTPPSLLNMYKELKDDLGC
                     FIPNNGYLMPWADQGVLLLNTALTVRAHEANSHKNKGWEIFTDRVISILSEREDPVIF
                     VLWGSNARKKVELIDTSKHYILEAPHPSPLSASKGFFGCKHFSKINEILKKLGKEPIN
                     WQIENI"
     gene            13946..14785
                     /locus_tag="KR294_001306"
     CDS             13946..14785
                     /locus_tag="KR294_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HBH0239389.1"
                     /translation="MNFKKLSNAKVSVMAVVLSVGILSGYSALNKQVTLVVRGEERTI
                     STFSSNVGDLLESQNISYDSNDIVTLDENTKLSNGDKIEVIDVKEKTVVETKDIPFEV
                     TVVEDGSLLKGDSKVKEEGKSGKSELIYKETYHNGKKVEKEFVKKVVKAEPVNKVVSK
                     GTKVEMQVASSRGESSRRMASSSSSSSSSNNGKNMRVVATAYTGHSITATGTKPKWGT
                     IAVDPKVIPYGTKVYIPQFDMVFTAEDCGGAIKGNKIDIYMNDSKTVYNWGRKTIDIR
                     ILK"
     gene            15029..15125
                     /locus_tag="KR294_001307"
     tRNA            15029..15125
                     /locus_tag="KR294_001307"
                     /product="tRNA-Sec"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:15063..15065,aa:Sec,seq:tca)
     gene            15280..15987
                     /locus_tag="KR294_001308"
     CDS             15280..15987
                     /locus_tag="KR294_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA threonylcarbamoyladenosine dehydratase"
                     /protein_id="HBH0239390.1"
                     /translation="MENNFTTRTSFLVGDDGIKKLNNSNIIVFGVGGVGSFTVEALAR
                     AGVGNITIVDFDDVDITNINRQIPALHSTVGRYKVDVMEERILDINPNINIKKIRSLY
                     NKDTSDEILTERYDYVVDAIDMVSSKIHLIETCEKKGLKIISSMGMGNKLDPTKIVVT
                     DIHKTSTCPLAKVMRKELRDRGIKKLKVVYSTEQPIELKKKVMNGRKVTPGSVSFVPS
                     VGGLIIASVIVNELLGQ"
     gene            complement(16129..16965)
                     /locus_tag="KR294_001309"
     CDS             complement(16129..16965)
                     /locus_tag="KR294_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBH0239391.1"
                     /translation="MRNKIFLSILIIISLLIGCDKKSLLSIHMIDVGQGDSILVQTPT
                     NKNILIDGGDEDSENIIISYLRQKRIKTIDIIIATHPDSDHIGSLDNIIKKFNVNSIY
                     MPEQSTDSKAYQNLINSCTDKNLSIQHLYKNDVLNIDNNINIYVLSPSYIQEESNLNS
                     IVFKLTFNDNSFLFMGDAEEENEKEILHSFKLNNINFIKIGHHGSNSSSSLEFIKKIS
                     PDIAAISCGYKNQYGHPHREVINNLKQNHVSIYRTDRIGDIVFYSDGEIIFTKYNYEI
                     DT"
     gene            17153..18058
                     /locus_tag="KR294_001310"
     CDS             17153..18058
                     /locus_tag="KR294_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2156 domain-containing protein"
                     /protein_id="HBH0239392.1"
                     /translation="MFFKDIELNSKKELDPYFDLVDYEACEYCFSTLYMWQHVYKTGY
                     YIGEDFAVLVGEYEGDSFSILPLAKKDKLPEVVDFVLEYFSKNNKKIYLRGITTEVVE
                     FLKEKYPGRFEYIEERDLFDYIYDAESLRTLAGKKNQKKRNHINYFLKEYAGRYEAKL
                     LDKENFDECLVLMKEWESNKEENNEFDESMDDELIGIKKIFNHYDILKDKVKVFGVYV
                     DGKLEAFSIGELLNPNMALIHIEKANPDIRGLYPFINQQFLVSEFKDVEFVNREEDLG
                     IEGLRKAKLSYHPCRFVEKYSVREA"
     gene            18067..19251
                     /locus_tag="KR294_001311"
     CDS             18067..19251
                     /locus_tag="KR294_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH0239393.1"
                     /translation="MEIRYAKEEEIESIKDIWSYCFNDTESFMKYYFNDKYKSENTVV
                     ALDEGKIISSLQLNQYKLLLNSKVYNTSYVVGVSTLPEGRGAGYMNKVMKFTLNELYK
                     KGQLVSILMPIDYRLYRRFGYEHCYDQIEYTINTDDLKNFKSSGKMIKSNLSQIDDLI
                     QIDRTFLNEVNGNVLKDEHYYENLFKEIQSEDGFLYIHEGNEKDGYIVYFLQEDKMFV
                     RELFYKNIDALKSMLKFIYNHNTQCKIVTISTPTIDKIRFILDNPKDSDIKIKPFMMG
                     RVINVKKFIEDIDIEKDINSSFNLLIEDKFIDENNGLFKISIQNKKVSVEQLDKKGAE
                     KPQEDFDIKLDINTLTQLSFSYIDVNEAIFLNDIKDVSEETLETLNCIFSKKNNYINE
                     YI"
     gene            19366..20667
                     /locus_tag="KR294_001312"
     CDS             19366..20667
                     /locus_tag="KR294_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEC/Rec2 family competence protein"
                     /protein_id="HBH0239394.1"
                     /translation="MGVIIIQIRRPLLIILMFVVAISFIITNNTKNDEELNDKIITIQ
                     GVVKGKIEKKRYNQYKVGVFLINDYTKNKNLKIGQKVNITGKFKSLDKMKYDDFDYGR
                     YIKSTGYKGIVYINNYKIIDKNKLYSLIGEIKFYISKTYRYLYKKNSDFINSILLAEV
                     ENLTEEQKEIFTRTGTSHVISISGLHTGILCVIISFLLRGINKLYKLLILSIFITLYC
                     IMVGASPSIIRSIAFVMIFYLSIFIDRKKDGISALSLIGIILIMNNPYVIYNVSFQLS
                     FLATLSILIFYNKINSIIKLSMVSLTISSNILTLPIIYYTFKGIPLLSIIGNLIIVPF
                     VGVIMYLSIASLIVFKVSVVIAKIISFFNSTFIESIFFLLEKISNLSFAYINIENPKF
                     YIVVIYYIGVFFYIFYIEGKEIKEQENELQGYYKECKREKL"
     gene            20621..21664
                     /gene="holA"
                     /locus_tag="KR294_001313"
     CDS             20621..21664
                     /gene="holA"
                     /locus_tag="KR294_001313"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HBH0239395.1"
                     /translation="MNYKDIIRNVKEKNFEKMYLFYGREYYLIENAIKAFKDSLNEGM
                     LDFNLDIIDGKEIVLNQLISSIETLPFMDDRKIVIIKDFELLKGKKKNFTDSDEKYLI
                     EHLDNIPDTTTIVFVVYGDVDKRKSLVKKIGNNGIVFDCDKLSDMDLFKWIKKSFALN
                     DVIIDNSQIMYFIEQEGYRDKSSEKTLSDLENEINKISSFVGKGNNVTNDVIDKLSQK
                     KVENDIFKLIDYIGEQNASNAMKILNDMIQEGESVLGIFSMIARQFKIIMQVRQLQLD
                     GYSTKLIADKLKMHQFVVGKALKQTKNFSDDIIVEILNYILESDYKIKTGLIRDTLAV
                     EMLVSRYCKREAI"
     gene            complement(21851..22117)
                     /gene="rpsT"
                     /locus_tag="KR294_001314"
     CDS             complement(21851..22117)
                     /gene="rpsT"
                     /locus_tag="KR294_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HBH0239396.1"
                     /translation="MANIKSAKKRISVIEKKTALNRVRKSQIKTAIRRFEDAVAAGNR
                     EDAVAKFQYAQKRIYQVASKGTIHKNAAARKVAKLAQKLNGMNA"
     gene            22713..23234
                     /locus_tag="KR294_001315"
     CDS             22713..23234
                     /locus_tag="KR294_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH0239397.1"
                     /translation="MDIAKLILNPARLRILQYIRLYGSVRTSDIVKYLNDIPRATVYH
                     HVKILEENNMIEVIKENRVRGTIEKVYALKEYTTSMEGETFVALSTAFYVGLMQEMNE
                     YFSRKEQDHKKDNVFFSSALLYMSDNEYENLLKSIADLLKPYIEQKPKSNLKLRKLSI
                     ISSPPVADNDKTK"
     gene            23268..24044
                     /locus_tag="KR294_001316"
     CDS             23268..24044
                     /locus_tag="KR294_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBH0239398.1"
                     /translation="MKFHEFGNKNRPHIMLIHGGGNAWWNYLRQAEVLSNKYHVILPT
                     LDGHGEEYETTYISTEDTADKLISYIDENCSGHLFALCGVSLGGQIVMELLSRKPNIT
                     KKAIIDGSICYPRPLMARFCIAGIRFFGGLLFSEKACRFQIAMMPKLLPENMQYPDEI
                     KAYYMTDMPHVRKETFYNMYRTYMMNYTLKENVKKTTAQVMYWYGEKEMKCVKKSAKL
                     FQSYVPSCEIYEAKSYNHGYLSLYLPNEWLEIAEPFFQKE"
     gene            24386..25339
                     /locus_tag="KR294_001317"
     CDS             24386..25339
                     /locus_tag="KR294_001317"
                     /EC_number="3.4.24.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GPR endopeptidase"
                     /protein_id="HBH0239399.1"
                     /translation="MISVRTDLALEASEMCEKSQEGSSIPGVKIETKELENCIVTKVE
                     VIDRQGAEIMNKDIGKYITLESNLMKFDDDESREEMISYLKEELVDIFGQDKNKKTLV
                     IGLGNRNITSDALGPKSVSKTLVTRHLFKNYNKDYDDDFTEVSALSPGVMGVTGIETS
                     EIVKSLVEKVKPDRVVAIDALASRKMERVNSTIQISTAGISPGGGVGNTRKSLTKETL
                     GVDVIAIGVPTVVDAATLTIDVLDMAIDNLIAQSEETESFYEMLKKLKEEEKYHLIKD
                     SLDPYDKNLIVTPKDIDDTIENLSIIISEGLNRSLHPGRLV"
     gene            25357..26376
                     /locus_tag="KR294_001318"
     CDS             25357..26376
                     /locus_tag="KR294_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein P"
                     /protein_id="HBH0239400.1"
                     /translation="MFKKCIKVVTLTFILVCILPGKSLALNQDDFLKFLVNSSYPEAK
                     VEGNDTENKKNNKNKETSKENKEESKEGNTKSKDASKVDNKKESEKEYIKLYVGKENV
                     PDIESKNSDTTETNTTSSSDYKDDLRVTKENPRILIYHTHGCETYSNSPDGNYHSRDK
                     KNSVMEVGSALTSALDSKGWGVVHTTKYHDYPSYNNSYASSLKTIQSILPKYNSVDIA
                     IDLHRDARDLTNPATKEKDHLKYTTMINGERVSKFFFVVGGKNTNRKQLRALAEDITA
                     FAEKKYPGLVSPIVEKDYARFNQFAVKNHMLVEIGNNATSVEESKATTKYLAEILDEY
                     FKQKN"
     gene            26407..26658
                     /locus_tag="KR294_001319"
     CDS             26407..26658
                     /locus_tag="KR294_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239401.1"
                     /translation="MSRLEKNIESKSKLRKYKYIMRILFLITMIICTSVCVFIVDSNA
                     KSMLGMKQYDFPSIKFDITKFDFDIPNFDIHEIIKKFNK"
     gene            26940..28745
                     /gene="lepA"
                     /locus_tag="KR294_001320"
     CDS             26940..28745
                     /gene="lepA"
                     /locus_tag="KR294_001320"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HBH0239402.1"
                     /translation="MDNKQSRTRNFSIIAHIDHGKSTLADRLIQQTGLVSERDMKSQL
                     LDNMDLERERGITIKLQNIRLMYKAKDGNEYYLNLIDTPGHVDFNYEVSRSLAACEGA
                     LLVVDAAQGVEAQTLANVYLAIDQDLEILPIINKIDLPSARPEEVKNEIEDLIGLDSS
                     EAPLISAKTGLNIEDVLEDIVKNVPPPKGDNEAPLKALIFDSYYDAYKGVVAYVRVFE
                     GTVKKGMTIKMMNTNKKFEVTEVGVMAPGQTELSELSAGDVGYIAASIKDIRSCRVGD
                     TITDSNNPTEEPLPGYKKATPMVYCGIYPGEGEKYENVRDALEKLQVNDAALEYEAET
                     SAALGFGFRCGFLGLLHMEIMQERLEREFNLDIITTAPSVIYRVTKMDGEVVMIQNPA
                     NLPEPSEIKMIEEPIVKGDIIVPKDYVGVVMELCQERRGNMLNMEYIDDRRVMLHYDL
                     PLNEVVYDFFDALKSRTRGYGSLDYEVKGYVASTLVKLDILINKEQVDALSFIVHETR
                     AFPRGKAMCEKLKGEIPRHQFAIPIQAAVGNKVIARETISALRKDVLAKCYGGDISRK
                     KKLLEKQKEGKKRMRQIGSVEVPQKAFMSVLKLDE"
     gene            28894..30231
                     /locus_tag="KR294_001321"
     CDS             28894..30231
                     /locus_tag="KR294_001321"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HBH0239403.1"
                     /translation="MINIEIPKKVDYIIKELEKNGYEAYIVGGCVRDCLLERVPNDWD
                     ITTSARPEVVVELFEKTIPTGIQHGTVTVMIEHEPFEVTTYRIDGNYSDGRHPDSIEF
                     TNNIVKDLSRRDFTINSIAYNSKTGLVDPFNGYEDIQNKYIRCVGNPVDRFEEDALRM
                     LRAVRFSAQLNFKIAEGTKQSIHKKADLIKNVSIERIQTEFNKILVSDSSKLNLLKST
                     GLLKFIIPEICELEDVTQHNPYHIYDVQKHTLIATEVIEDELYLKLTMLFHDLGKKVT
                     KTTDKNGVDHFYTHSRESVKIAKKILKRLKYDNYTINKVLILIQYHDYRIEPKRKIIK
                     KLLNKLEDVELFEDLIKVNWADTLAKNPKYAKQKILNLIECEKEFKHIINQKECFNLK
                     DLAINGKDLISIGIKPGKDIGYILNKMLEIVINNPELNEKEILKEKALNIYTF"
     gene            30464..31777
                     /locus_tag="KR294_001322"
     CDS             30464..31777
                     /locus_tag="KR294_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBH0239404.1"
                     /translation="MHTQLQKTIGLSAALSTVVGMVIGSGVFFKPQAIYTTTNGAPGL
                     GIIAWLLGGFITITAGLTATEISAAIPKTGGMMIYIEEIYGEKLGFLTGWMQTVLFFP
                     GTSAALGVIFAQQASELLGMSPNNMANVLPIAIGVILFLALLNIIGSSLGGKVQTVAT
                     IGKMIPLILIIVFGFIKGQSSEVLNPFVGDGVNASNALGQVLIATLFAYDGWINVGAI
                     SGEMKSPEKDLPRAIVGGLSLVMAVYIIINIAYLWVVPASELATVTSPATLVATRLFG
                     NIGGKVITVGILISVFGTLNGYLLTGSRIPYTLAEMGTLPASKTLLKVNSGGSPVNSI
                     LLITVLACVYALSGQFNLLTDLTIFSIWVFYVLTFIGVMRLRRQKPDLHRPYKVPLYP
                     IIPIIAILGGLFVIINQILTSTVISLGGIFITLLGLPVYYYMKKR"
     gene            31949..33124
                     /locus_tag="KR294_001323"
     CDS             31949..33124
                     /locus_tag="KR294_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HBH0239405.1"
                     /translation="MLGLYVHIPFCVKKCKYCDFNSYKMDIDSKKRYIEDLKIEMELY
                     SNKLYKDNKYKNKECCSLNKNDKITSIFVGGGTPSILTSDEIREVFISIKEMFDIDEN
                     AEITIECNPGTLTLEKLKTMKEIGINRLSIGLQAIQEKHLNFIGRIHTYEEFEKNYKD
                     ALSVGFKNINIDLMYSLPNQTLCDWKETLEKVVHLNPTHISAYSLILEEGTELYNMYE
                     SNKFELIDENVDIEMYEYTINYLKSKGYNQYEISNYSKEGYNCEHNILYWECEHYIGI
                     GAGASGYINENRYNNVESLEDYHLSLVKREKPIQENEILSEKDMIEEKIFMGLRMNKG
                     IKFEDFKKKFGIDFREKYNKQIEMLLARKLINQSFEGIQLTQKGREISNSVFIEFME"
     gene            33227..34246
                     /gene="hrcA"
                     /locus_tag="KR294_001324"
     CDS             33227..34246
                     /gene="hrcA"
                     /locus_tag="KR294_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcription repressor HrcA"
                     /protein_id="HBH0239406.1"
                     /translation="MELNERKLNILKAIVKDYIETAEAIGSRTISKRHDLGVSAATIR
                     NEMADLEELGYLIQPHTSAGRVPSEKGYKLYVNSLMSKSELDDNDKILIEQCMNHNIN
                     HIKELIHETSKLLSQLTNYTTVAVTKSLINQSVIKHIQLVAMNDNNILLIVVTDKGDL
                     KKANLTTNVYLDQSKLNLISDNLTRKLLGKSITDLDDNLIAFIKYEISEYSGLIDELL
                     NALNSNMKEEDFSLSLNGATNIFSYPEFNDVLKAKSFLNMLEKKETIADIIKSKGIQK
                     DNLNIIIGSDNDCELAQDCSIVTATYNVDRDLVGRISFIGPTRMDYARIYSIINYMSL
                     LINRK"
     gene            34276..34896
                     /gene="grpE"
                     /locus_tag="KR294_001325"
     CDS             34276..34896
                     /gene="grpE"
                     /locus_tag="KR294_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HBH0239407.1"
                     /translation="MDKKNEQQEVREENDTSINQESETQVELEEEVVNEECETSSEKT
                     DEKEVDDENVTDINSKLAEKKLQDELDELNDKYQRLQAEYANYRRRTQQEKETIGVFA
                     NEKIITELIPVIDSMERALDACEDKEDTMYKGISLVHKQLIDTLVKFGVEEIEAESKE
                     FDPNLHLAVMQESVDGVEANQIVMVLQKGYKLGTKVVRPSMVKVSC"
     gene            34988..36835
                     /gene="dnaK"
                     /locus_tag="KR294_001326"
     CDS             34988..36835
                     /gene="dnaK"
                     /locus_tag="KR294_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000034699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HBH0239408.1"
                     /translation="MGKIIGIDLGTTNSCVAVLEGGEAQIIANSEGMRTTPSVVAFTK
                     DGERIVGEPAKRQAVTNADKTITSIKTHMGTDYKVNIDGKSYTPQEISAIILQKLKSD
                     AESYLGQTVTEAVITVPAYFTDAQRQATKDAGRIAGLDVKRIINEPTAAALAYGMDKL
                     DQEKKILVFDLGGGTFDVSILEIGDGTFEVLATAGNNRLGGDDFDQIVIDYLAEEFKK
                     AEGVDLRNDKMALQRLKEAAEKAKKELSSTMSSNINLPFITATAEGPKHLNIDLSRAK
                     FEELTRGLVEKTMEPTKTALQDAGLSTGDIDDVLLVGGSTRIPAVQEAVKKFIGKEPH
                     KGINPDECVAAGASIQAGVLAGDVKDLLLLDVTPLSLGIETMGNVMTKIIERNTTIPT
                     KKSQIFSTAADNQTAVDIHVLQGERSMAYDNTTLGRFQLTDIPPAQRGIPQIEVTFDI
                     DANGIVNVSAKDLGTGKEQKITITSNTNLSESEIEQKIKEAEMNAEADKQKKEKIEAF
                     NQAESTIYQTEKTLNELGDKISSGEKEDIEKAIADLKAVKDNQDATAEELKKATDEVM
                     TKFQKVSQEMYQKAAQEQQAAQGAEQAQDNGPKDDNVVDADFKEVDEDK"
     gene            37046..38200
                     /gene="dnaJ"
                     /locus_tag="KR294_001327"
     CDS             37046..38200
                     /gene="dnaJ"
                     /locus_tag="KR294_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HBH0239409.1"
                     /translation="MSTKRDYYEVLGISKGAEAQEIKKAYRKLAMKYHPDRNPGDKEA
                     EEKFKEINEAYEVLSDDTKRKTYDQFGHDGLNGQGGFGGQGGFGGQGFGGFEDMFGDI
                     FGDMFGGSFGGGRARRRGPQRGADIRQSVTISFEEAAFGKKMSIKVNRSEECEECNGT
                     GAKPGTSKKTCSTCNGTGQVRTVQRTPFGNIASSRPCSACNGTGEVIESPCSKCHGTG
                     NTRKVKTIEVDIPAGIDDGQMIKLSGQGEVGEKGAPRGDLYIVVNVKSHPLFTRDGND
                     IYFEMPITFVQATLGDEIEVPTLDGKVKYSVPEGTQTGTVFRLKEKGIPRIRGNSRGD
                     QYVKVVVEIPKKLNDKQKELLREFAKECGSNVHEKKKTFGQKIEDMFKKK"
     gene            39166..40101
                     /locus_tag="KR294_001328"
     CDS             39166..40101
                     /locus_tag="KR294_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBH0239410.1"
                     /translation="MYYIGVDIGGTGIQAGVVDNYGKIIFRSECKTVIEKGFEGILND
                     IKIMIYKLLEDNKLTMSDIKSIGFGVPGFINKEGLVTCVNLKWNKKAFNKELKKRFPD
                     VEIHGENDATVAALGEAKFGSMKGANVGVLYTLGTGVGGGIVINQKVFSGAHGLGSEI
                     GHQIIGENYFNCNCGNNGCVETFCSATAIIKYSQKLIEEGEKSRILDLAEGNLENVNA
                     KMVFDAYRENDLVAIKVINRFKEYLAKTFANTINSLDPEIISIGGGISKSSDIILDGI
                     EGLVRKFVLYKTEDIATITCATLGSDAGIIGAAFL"
     gene            40137..41510
                     /locus_tag="KR294_001329"
     CDS             40137..41510
                     /locus_tag="KR294_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH0239411.1"
                     /translation="MGKTNARRTLFLIAIGSGTMLNPLNSSMISLALHSIQNDFHISF
                     TTVSWIVSAFYLASAIAQPVSGKIGDLIGRKVLFLSGLMLVILSASIVPLVQSFFILI
                     FIRVIQAIGTSTLYPSGVALIQNNIKERQSSALAVLTIFASTTAGLGPTLGGLLLDLG
                     GWHAIFLVNIPVVLVSICLGYFLFPKEVKEKKSIKETLKNVLSRLDIIGILLFSIAMI
                     FILLFLLSMKESFNLEQLVFGIILMCLFIWHELRTKLPFIDIKLFVSNPKLSKVYLQF
                     IILNFFNYILFFGLPSYFQDALHYSAKSTGLFMLFMSGIGIFISPLTGKWIDKSGTRF
                     PLVTSSIFMFISAVLLSVVFIHIPVIGKGIILSLAGISYGVGNVALQSSMFEESPRDS
                     IGTASGLFQTSRYLGSILATVLLGMVFEVNITSEQFQILGYVMVVLGTISFLLNFILK
                     KELRKVE"
BASE COUNT        16609 a         4398 c         7204 g        13584 t
ORIGIN      
        1 tagtggaatt gaattaaatt caagttcaaa taaaggtaaa tgggaatatg atgaaaaaaa
       61 gatttttaac agaataatag taataataat cttatcaaga gttccaaatc tattgcatat
      121 agttattgat aatagaaatg tagagaggat attatcacaa ataataataa atgtagcctt
      181 atattattta tataattaca tagtatctaa gaatattaag aaaacagcac tggaattgca
      241 tgatacgaat gaagaattaa caaaaaaaac ggaaagttta aaagaaaaga ataaaaaatt
      301 aatctatgag acagaaaaga tagaggaact taagggaata cttatgaaaa gagaatctag
      361 gctacaatct acattagatg tagcagtaaa tagcatagta gtatttagca aagatggaga
      421 aattacatat gcaaataaga gctttagaaa tacttttgga gactataaag aacaagataa
      481 attgactgat aaaataaaaa acttcaatga tttgatagaa agcattcatt atgtgtttgt
      541 tcatgagaag aatgcagaga aacttattag tacaagcgat aataaagttt atcaagctat
      601 atttgcacct ttaattattg cttcacaaac agaaggagta ttgtgtgtac tagaagataa
      661 gactaagaaa aaggagtacg aacgcaaact tattgaagca aataagagaa gtaaagattt
      721 tttagaaagt attggagatg gcatagtagt gcttgaaggt aataacaaaa tatatgttaa
      781 taatgcatgt agggaaattt ttaaaaataa tttagagagt attgattttt cattagtatg
      841 taaaagtgaa gaaagtatag aaaaaagata tgtaatagat ggtgaagtaa agtatgtaga
      901 gatgagtttt tctcagtata ctaatgctgg tactaataaa actattattg taatacgtga
      961 tacaacctct cgaaaaatat ctcaaataaa acttgaggaa agtcaatcat catattcaag
     1021 atttatagat atattacctg atggcatatg cttattaaaa gaagatttaa gtataaacta
     1081 tgcaaataag tcgtttttag atatgctagc ttttacaaac atagatgata taaaagattc
     1141 taatattaaa ctattaatga atgcgaatac tgaagaaaaa atgaaattta cggataatat
     1201 ggctaaagtt ttaaatgaaa atagaagtat acttttactg gaatatgaat tgataaatag
     1261 ttatgatgat atagtagaag tagaattaag tgcattacct tttgctatat acaatactag
     1321 atacataatg cttattataa aagatttagt acataagaaa tattccgagc aagcagaaaa
     1381 agaactgctt gaaagattta aaacagataa aatcaaaacg gagttttttg caaatatgtc
     1441 tcatgaacta aaaactccac taaatgttat atctagttca aatcaactgg tagattcttt
     1501 ctatagaaat gaaaagataa aagattacaa taacaatatt aaatctcatg tggatttagt
     1561 tagacaaagt tcttataggc ttcaaagatt aataaataac attatagatt taacaaagat
     1621 ggagtctggg ttctatacac taaaacttgc gaaatacaat attgtatctg taatagaaga
     1681 cttatttatg aatatagaag agtatgcact tagaaaagac ataaaaattc tttttgatac
     1741 agaccttgaa gaaattaatg tttatataga caaggttgaa attgagagaa ttatgttgaa
     1801 tctattgtca aactgtatta agtttactga taatggaggc tggatatatg taagtattca
     1861 ttataaaata gataaagtaa tcataagtgt aaaagacact ggagttggaa taccacaaga
     1921 taaattagag ttgatttttg aagaattttc acaagttgat aagactttat ccagaaatac
     1981 tgaaggaagt ggaatagggc ttgctatagt taagaatcta gtaagtcttc atggtggaga
     2041 tatagaagta gtaagtgaag tgaataaagg cacagagttc ttaatttcac ttccaatgaa
     2101 gggatttagt agtgaacatt acacagaaga taagagaata tataatattc aagaaaaaat
     2161 aaaaatagaa ttttctgata tatattatta aaaatgatta tgagcaaaaa taaaataaaa
     2221 atactatttg tttaaatatt taagttgtaa gaaataggct atcataaggt aaattattat
     2281 gatagcctat ttttagctag gttttatatc tatatgtgag aacatataat ctctaaatta
     2341 ccttcaaaac taaaatctcc aaagtcgttt ggtagtataa aatgcatacc cttttttaaa
     2401 ttgtattcta cagaattgtg tataagtttt ccatttccat ccaacacact gtataaagaa
     2461 aaaggtgtat tgtgtgtaaa attacatttt ccaaaaacat ctaatttata aacactaaaa
     2521 aattcgtttg acacaaatgt tgtgcattta aagtctgatg ttgatacgat tttatagtca
     2581 gtatcgaaat ttatatgagg aacattcgta acatctattg atttttgaac atgaagttca
     2641 cgcttattac ctgaattgtc agttctatca taatcataga ctctataagt agtatctgag
     2701 ttttgttgag tttctaaaat caatgttcct ttgcatatag catgtatagt gccacttgga
     2761 acatagaaaa agtctccctt ttttatatta acctttctaa gtagtttgtc ccattcatta
     2821 ttatttacca tatttacaaa ttctttatga gattttgcat tatgacctat tataatttct
     2881 gcatcatcag aacaatctat tacataccaa cactctgtct tacctaactc tccattttca
     2941 ttttttttag catattcatc atttggatga acttgaactg ataaattatc atttgcatcc
     3001 aatatttttg taagtaaagg aaacttatca ccaggtgtgt ttccaaataa ttctctattt
     3061 ttattccaca attcagatag ttttttacct ttatattttc cattttctat taagcaatct
     3121 ccatttttat gagagcttat agcccaacat tcaccagttg ttggcgaatc tatttcataa
     3181 ttaaatttat ctttaagtgc agtaccaccc catattctat ccataaaaat aggttttaaa
     3241 aataatggtt ccataatcct gttcctccta tgatattaaa tttatcctac aaataattat
     3301 atataaatag attataaaat caatagtaaa aaagttttgt cccttgaaat gacataaagt
     3361 ataaggagtt attaaataag ataaactatg atatataata taaagttcta aattggagtg
     3421 ataattatgg agttgtttaa ggcagaaagc aaaaaatata aaaaagaatt tttaaaatta
     3481 ttggagcaat gggttagtat accttcattt tatgatagaa aaactgtatc taaagacatg
     3541 ccttttggaa aaggagtata tgatgcatta aactggtttg aaaatctagg tagagaaaac
     3601 aatttcaaag taaaaaatat agataatcat gctgttcaaa ttgaatatgg aaatggtaaa
     3661 gagtatgtag atatatttgg acattgtgat gttgtaaatc caggtgaagg atgggatagt
     3721 gaaccattta aactaaatat tataggtgat aaattagttg ctagaggtgt atctgataat
     3781 aaagggccta tgatagtgaa ttttttagca ctaaaaatga taaaggattt agatattaat
     3841 ttaaaaagaa aggttagatt aatagctggg ggaaatgaag agagtggatt taaatgtata
     3901 aagcattatt atagcaaaga gccatatggt gtatgtggat ttactccaga tgctaaattt
     3961 cctgtattaa atggagaaaa aggtggagca ataataaagt taatttcaaa tatagacgat
     4021 aaatctttat atataagtgg tggaatagag tttaatacaa taccagataa agtttatata
     4081 aagaatgtag aaaaattggg taaagataat atatgttttg atattaacaa tatatcgata
     4141 aattatgata atggcaatta tattgtgtat ggaaaaggtg gtcattcatc taaacccgaa
     4201 aaatcaataa atcctatatt agctacaatt aaacttttgt cagaaaatat tgatgaaaaa
     4261 tggacaaaag atttatataa gttgataaat caagataata taaatggaaa cttatttggt
     4321 ttaaatattg aggggaaatg tggaatttta tcaatggtgc caacaataat aaatatagta
     4381 gatggaaaat tagaagtagt tttaagcgtt agatatccag aaatattaac cattgaagat
     4441 ataataaaaa aatttaattt gtatatggag caaaataata ttaataaatt tgagcttatt
     4501 ggggaaaatt taaagcaagc aaattatata gatagaaatt caaaacttgt aagaagtttg
     4561 catgatatat atataaagta ttctggagat ttaaaaaatg atgttagagt aactagtgca
     4621 ggaagttatg cttctgaaat gaataattca gtaatatttg gttgtgaatt tcctgatggt
     4681 agctttggca atgtccatag tgcgaatgaa tttgctagct tagatagatt tataactgca
     4741 ataggtatat atgcagaggc aataattaca ttatgtaata aaatataaat acaaaatgtc
     4801 ccttatatag acatattata tatacaatta aaattttact tgatatataa ttgaaatcaa
     4861 agagaaggtg atacaatgat aactaagaaa catgcaataa tagtaaagag tttaagcaat
     4921 aaagatggat atatgacatc aaacgaatta gctatcaaat tggatgtgtc tactaaaact
     4981 attaaaagat atatagcaga tttaaatagt gttttaagca aatatgattt ggtaatagct
     5041 tcttctagag gtataggata caagttaagc ggttctaaaa acaatatagc cagagctgtt
     5101 aaagaagcaa ataaatatat tgatggtttt ttagatgact ctgaagagtc aagaatgtca
     5161 aatataatat gtatgcttat taatagaaat tatatgagta tagaagcaat ggcagaagaa
     5221 ttaaatctaa gtatagccgc tataaataaa ttgtctagta agcttaaaag aaaacttgaa
     5281 aagtatgact tagttataaa atctaaacct tactatggaa gctatataca tggtgaagaa
     5341 attaatataa ggcaattaat tactgactat gcaataaaat tagatgaaaa aagtaaagtg
     5401 aaggtgtttt tagatgacat tagtgaaaac gatatacact gtatagaaag tattttagaa
     5461 aagcacttaa gagaaaaaga tacaataatt tcagataaag attttaatct tttgctttca
     5521 aaaataatcg tttctgtatt taggagtaag agaggtcata gtaacaatat aaacttaatg
     5581 gatacaagtt atagatttca taactactac tttatagaaa atctaatgaa agaaatatct
     5641 gataaaattg gatttaaact tattgaagat gaagtaattt atatttcaaa ttattctggt
     5701 gtaatagcct ataaaggtac acaaggaaga aaaaacacaa gtgaaattga ggaacgaata
     5761 agtactgtta taagtagtgc acttcaagat atattcctta tttcaggtag tgattataca
     5821 aaagatgatg agtttatggt tgcaatctct gaccatataa agagattttt aaatagagct
     5881 agagctaatg taaaatcaaa taatccttta cttcatcaaa taaaagagaa gtttcctata
     5941 gcttttaatt tagccgtgtt tttatcaaat aaactagaaa ctgagtttaa tttaaaactt
     6001 gatgaagatg agcttggata tatagctatc cactttgctg cttcaaatga aagaatgaaa
     6061 aaaaatacta gtaagaaaat ttgtatagtt tgtcattatg ggataggaac aggacaactt
     6121 atttctgaaa agctaaaaca gaatataagt gatttaagtg ttgtgggtgt ttatccagtt
     6181 agatatctcg atatggctat aagtcaagat gttgatttga tagtatctac agttgaatta
     6241 aaaggatatg aaaaacctgt cttatatata gaaaatatat ttgatgatag cttaattgaa
     6301 aacgtaaaca aagcctttta tgaaaaggaa gaaagaagaa agataataag taacatgttt
     6361 gatgaaaaag cttttttcag tataaaggct agtactaaag aagaggtcat aatttcactt
     6421 tcaaataaac taaaagaaag agattttata gaggaaagtt ctataaaaag tataatagat
     6481 agagaaaata tttcatcaac tgaaatagga aatctagtag caatacccca cacaatagtg
     6541 aagggagata aaaaatctat aataggagtt ggaatacttg aaaatccaat aatttgggat
     6601 aagcaagagg ttcagctagt atttatggta ttttttaata ctaaagaaaa acataatttc
     6661 tcgatattta aataccttta taattttata aaagatgaag gaggagtaag aggaattatt
     6721 aaaatatgtg actttaataa attaatggca cttataggta attaaggagg aaattaataa
     6781 tgggaacaaa catatttaac aaagaatatg tatttttaaa tgttgatgct aagtcaaagg
     6841 ttgaagtttt aaaatttata tcaaaaaaag ctaaagactt aaacttggca gaagatgaga
     6901 gcttagtata tgaaggttta atggctagag aagaacaatt tactacaaat ttaggagaat
     6961 ctatagcaat acctcacact aaaaatgatg caattgaaaa tccagcagta gtagtattga
     7021 agtttaatga agatgttgtt tggaatgaag gtgaggataa ggttaaatta gcaataagct
     7081 tacttatgcc aggaaaaagt aaagagaata ttcatcttaa attattatca tctctttcaa
     7141 gaaaattaat aaataaagaa tttaaagatt ctcttttaaa aagtgataat gttgaagaaa
     7201 tatctaactt aataaatgaa gctttaggtt tataattaaa cactaaggtt ataaaataaa
     7261 aaaataatta actaaaaata ggaggaattt gaaatgaata aaaaattagt agcattatgt
     7321 gcttgtccaa tgggactagc tcacactttc atggcagcag aagcaataga gcaagcagca
     7381 aaggcattag gttatgaagc aaaagttgaa actcaaggtg ctgatggtgt acaaaatgag
     7441 ttaacaagag atgatatatt aggagcaact atgataatac atgcagtagc aataacacca
     7501 gaaggtatgg aaagatttga tggttgtgaa gtttatgaag ttgaattaca agaagctata
     7561 aaaaatgcag aaggtgttat aaaagaaata gaagaagatt taggaatata ataaatttat
     7621 tgtggaggaa atagaatggc aattaagaaa aaagttataa acagttcagg tgcttctaca
     7681 acaggaggaa ataatgtagg aaaatctact ccatctagtc caactcaatc aaagggaaat
     7741 ggaaaatgga aagaaataag taaacatata atgacaggta tatcatatat gataccagtt
     7801 ttagtaatgg gtggacttat aggggcctta tctcaattaa taccatatgc tatattagga
     7861 cttgacccat ctgtaggtat agttgatgct atgaactcag gagaatttac agggttcaag
     7921 cttagtcttt taaatatagc acaattaatg tcaaatttcg gatttacttt gtttggattt
     7981 gcgataccac tgtttgcagc attttgtgca aactctatag gtggaaaaac agctttaatt
     8041 gcaggattta taggtggata tatagctaat aaacctgtag gtgtaccaca attcgttgat
     8101 ggacaatgga ctgaagttgt tccagttgca tcaggatttt taggtgcaat actaatagca
     8161 tttataatag gatattttgt aaaatggtta aataaatcta taaaagtttc tcataactgg
     8221 ttagctttta aaacaacatt tttaatacca ttaatagcgt cattagcttg tatggtattg
     8281 atgatattta taataactcc atttggtgga ttaattaatg aaagtatgaa aaacttctta
     8341 acagcagcag gagcagctgg agaatatgta tatgcaacag ctttggcagc agctacagca
     8401 ttcgacttag gaggaccaat aaataaagca gcaggattcg ttgcacttgg tttaactaca
     8461 gagaatgtac ttccaataac agcaagaaca atagctatag ttgttcctcc aattggatta
     8521 ggattaacaa cattattaga taaaagatta gtaggaagaa gagtatatga tagacaattc
     8581 tatcaagcag gaaaaacttc tatattctta tcatttatgg gtatatctga aggagcaata
     8641 ccatttgcac ttgagagacc aggttttgtt atacctttaa acatagttgg aagtgtaata
     8701 ggagctatta caggtataat tctaggagca attcaatggt tcccagagtc agctatatgg
     8761 gcatggcctc tagtagataa cttatttgga tatataatag gtatagcagt tggtgctata
     8821 ttcatagcag taggaaatat attctataga aataaattaa taaaagatgg taaacttgtt
     8881 gtagattata tcgactagta tttaattttt actatctata aataactttg gctggtaata
     8941 tggttttaat caatattacc agccttacct atatgattaa ttaaaggcgg tggagataag
     9001 atatggataa gatagaaaaa gtaagagagt attttagaga atatgatata gatggatttc
     9061 ttataaatag tcctacaaac aagttttatg ttggaaattt atttagctct tcaggttatg
     9121 tttttataac taaagaatca caatatataa tagtagattt tagatatttt gaagaaatta
     9181 aaagaaaatc tagtttgttt aatgtagtat taatggacaa aactagaact cattttgata
     9241 taattaatga tatttgtaga gagcagaata taaaggaaat tggatttgag ggaaatgaag
     9301 tatcttttga tttatataga agtatgagta ataagttaag tgcaacctta aaatcagttg
     9361 atttatctac attaagggaa acaaaaaatg aagacgaaat aaaatatata aaaaaagctt
     9421 gtgaaatagt tgatgctaca ttttatcata tagtagactt tataaaggtt ggtatgactg
     9481 aaaagcaagt tgaaaatgaa attgttagaa ttataaaaga tttaggtggt caaaaagaat
     9541 ctttcgatac aatagttgca tctgggctta gaggagcatt acctcatgga aaagcaagtg
     9601 aaaaagttat agagtatgga gattttgtta cctttgactt tggtgctaag tataataatt
     9661 attgttcaga tattaccaga accatttgta tgggtactat aaataaagag ttagaagaaa
     9721 tatataatat agtaagaaaa gctaatgaag agtgtataag ggttttaaga ccgggaatga
     9781 ctactggaga gatagataaa gttgcaagag acataattgg ttcatatgga tatgccaata
     9841 attttggtca taatctgggt catggtgtag gaattatggt tcatgaatat cctgcattag
     9901 ctcctgaatc aaatgaagta ttaaaagaag gaatgattgt aactatagag cctggtatat
     9961 atgttccaag tcttggaggc gtaagaatag aagatgatgt acttataaca caagatggat
    10021 gtatgagatt gactacatct actaaggatt taatagttgt aagctaaaaa taaattagat
    10081 aaatatttta taacaataag aaaagaagag gtaaatttaa atgtataatt ttgatgataa
    10141 accagataga gtaagtgaaa agtgtagaaa atgggattta aatattataa gagataaatt
    10201 tggagatatt agagaagatt ttataccaat gtggattgct gatatggatt ttaaaatacc
    10261 aacagaaata gaaaacaaat ttattgaagc tgtaagaaga ggtgtatttg gatatacata
    10321 ctgttatgat gaattttatg attcagttat tggttggcaa aaaaatatgc atgaggtaaa
    10381 tgtagaaaaa gaatggatta cattaactta tggaactgta tcaacacttc attatgtagt
    10441 acaagctttt tgtaagaaag gtgatagtat aatattaaat acaccagttt atgacccctt
    10501 tgaatcatca gcaaaaaaac aaggtgtaaa tgtaatttgt aatacattag atgttgtaaa
    10561 tgatagatat tatataaatt ttgataaatt agaagttcaa attaaagaaa ataagcctaa
    10621 attaatgatg ttttgtacac cacataatcc atctggaagg atatggacaa ttgaagaaat
    10681 gacaagggta gcaactatat gtaaagaaaa taatgttatt ttggttgcag atgaagtaca
    10741 tgcagagcat attcattatg gtacatttaa ttcaatactt aagattggaa aagagctttt
    10801 agaaaatgtt attctattga catcaccaaa taaaggattt aatcttggtg gattaaagac
    10861 ttcttattca atagttataa ataaggatat aagggacaaa tttagaaata aattaaagca
    10921 aaattctata acttctccaa atgtgtttgg aataatagga ttgataaccg cttataatga
    10981 atgtcatgag tggttaagtg gtgtaaatga atatataaaa tcaaattatg aacttttaga
    11041 aacttgggta aataaatata ataagataaa attgatgaaa atggaatcat cttacttagc
    11101 ttggatggat ataagtggat taggtattag tgcaagtgag tttacagata aattggctat
    11161 agatacagga gtattattag aagatggaag tcattttgta aaagatggtg agaagtatgt
    11221 tagaataaat ttaggaactc aaaaggaaaa tgtaattgaa gccttaaata gaatggattt
    11281 atttttaaag tctttataaa aatttggttg aattagtatt ttatataaat ttaaactatt
    11341 aatatggtat atacataagt agaatttgtt ttagattact taagtatata ccatatttta
    11401 tataaaaatt aaatttgcat tagtcatgtg ataactattt aaattcatat gtattttgta
    11461 tgtataatag atataattat tatttaaact tattgtttat ttaatttttc aatagaaaaa
    11521 gatttatctg taagtttaaa attatctttt atacccttag ttaagtatac tttcttatcc
    11581 ttagttatga atatagcatc tacattatca attttattaa ttaaattcat acctttttca
    11641 agaccaagac caaatgtaga agtggataag gcatcacaat taatagattt atcagagatt
    11701 attgtaacac tacttaaatt gttttcaaaa ggataccctg taaatggatt taacatatga
    11761 tgatatattt ttccgtcttt ttcgataaat ctttcataaa ttccagaagt aacaacagac
    11821 ttatttgtag tttctatgtt tcctatggat tcaccatttt tactagttgg gtcttgaata
    11881 cctattttaa aaggtttatc atttttacca ttttctaaag taaatatatt tcctcctaag
    11941 tttactaaac ctttttttac atcctctgat tttaaatagg ctacaatttt atcagcagca
    12001 tatcctttag ctatggcacc taaatcaatt ttcatatttt ctttggttaa ttttatagat
    12061 ttattttttt catccaatat gatgttctta taatcaataa gaggcagaag tttttgtatc
    12121 ttagaatcac ttggaacttt agctttatct gttccaatag cccataaatt tgataatgga
    12181 ccaattgtta tgtcaaaata tccatctgat aatttggaat attgtatagc ttcttttacg
    12241 acgaaaaatg tatcatcaga aactctgaca aattttttac cagcattatc atttatttta
    12301 gaaacatcac ttcctggtat atgagtgctc attttgttgt caatatatct taaaattgaa
    12361 tcacattcat ttaagatttt atcacttttg gattctttta cattaaatac agtaacttcg
    12421 tttactgtac caaggtagta gctagtttta ctatatttag tattctggct tgaactccta
    12481 aaaaatgaaa ataaaattaa tgctaaaatc aatatcacaa aaataaatgt gatttttttc
    12541 ttattcatgg tatattcctc ctatgaaatt gtgttattat tttattataa cataatttca
    12601 taggaggaca aaaaatgaag aaaaaagaca ttcttcttat tttaggcatt ttggttgtta
    12661 ttacagcatg ttatgggata ataaatgtta taaattctaa aaatgctgga aatattgaga
    12721 tttatgtaga taataaattg tataaaactg tttcaataaa tgccaaagaa gaatttaaaa
    12781 tagagagtag aggggggtat aacatagtaa agattcatga taaaggggtt gagatagtag
    12841 atgcttcatg ccctgataag gtttgcgtac atactggatt tataaacaag ccaagtcaaa
    12901 gcatagtttg tatacctaat agagtgagca taaaaataaa tacaaatgaa aagaatgata
    12961 atcaagaaga tataatttct aaataaaata ataaaaataa ttgaaaggaa ttggtgataa
    13021 ttatggttaa cttaggaaac gattgggatg aattattgaa agaagaattt gaaaaagatt
    13081 actacttaaa cttaagaaaa tttcttatag aagaatataa aacacgccaa attttcccaa
    13141 atatgcacaa tatatatgaa gctttaaaac acacttcata caaagacaca aaagtcttaa
    13201 tattaggaca agacccttat catggagata atcaagctca tggtttagct ttttcagttc
    13261 aaccacaagt gaaaactcca ccatctttat taaatatgta taaagaatta aaagatgatt
    13321 taggttgttt tatacctaat aatggatatt taatgccttg ggcagaccaa ggagtgttac
    13381 ttttaaatac tgctcttact gttagagcgc atgaagctaa ttctcataag aacaaaggat
    13441 gggaaatttt cactgataga gtaatatcta ttttaagtga gcgtgaagac ccagttattt
    13501 ttgtactatg gggaagtaat gcacgtaaaa aagtagagtt gattgataca agtaaacatt
    13561 atattttgga agcacctcat ccaagcccat tgtcagcaag taaaggcttt tttggatgta
    13621 aacacttctc taagataaat gaaattttga aaaagctagg aaaagaacct attaattggc
    13681 agatagaaaa tatataaaag taaaaggtaa caaaatgata acaaaacaac aataaacaat
    13741 gacattgttg taactaatag aaatatgctt aaatagttga aaatactatg tatgcatatt
    13801 tctatttttt tgtcaagttg acaactcttg aaaaaatagt tacaatttag ttacacaaaa
    13861 aacacaaata aaaaaagaaa cttacaaagc agaattttat gaagcaaaat atatagtgta
    13921 aaaaatctta gggaggaaat tttatatgaa ttttaaaaaa ttgagtaatg ctaaagtctc
    13981 ggtaatggca gttgttttat cagttggaat attatcggga tactctgcgc ttaataaaca
    14041 agtaacatta gtagtaaggg gagaagaaag aactatatca acatttagtt ctaatgtagg
    14101 agacctttta gaatctcaaa acattagcta tgattcaaat gatatagtaa ctttagatga
    14161 aaatacaaag ttatctaatg gagataaaat agaagtaatt gatgtaaagg aaaaaacagt
    14221 tgtagaaact aaagacattc catttgaagt tacagttgtt gaagatggct ctttattaaa
    14281 gggtgattct aaggttaaag aagaaggaaa gtctggtaaa agtgaattaa tatataaaga
    14341 aacttatcac aatggaaaga aagtagaaaa ggaatttgtg aaaaaggttg ttaaagctga
    14401 gccagtaaat aaggttgtaa gcaaagggac aaaggtagaa atgcaagtag cctcatcaag
    14461 gggagaaagt tcaagaagaa tggcttcatc atcatctagt agcagtagta gtaacaatgg
    14521 taaaaatatg agagtggtag caactgcata tactggtcac agtataactg caacaggaac
    14581 aaaacctaag tggggaacaa tagctgtaga ccctaaggtt ataccatatg gaactaaagt
    14641 ttatatacct caatttgaca tggtgtttac tgcagaagac tgtggtggag caataaaagg
    14701 aaataaaatt gatatctaca tgaatgattc aaaaacagtt tataactggg gaagaaaaac
    14761 tatagatata cgtatattaa aatagttaaa taatttatat ttttactgga aattatattt
    14821 tgattatata gagaagaaac tctttataga ttctaaaaat ataatttcca gttttttatt
    14881 ttggatatgt aataaaacag gtaaatttta accatgtata gataaaagct atttaaatta
    14941 taatttacta tcatataaat ctataaaaat tgttgcaaag agtcaaaata tatgatatta
    15001 tagatttcgt tgagaaggat ttcattatgg gagtggatgg gtgccggtgt gccctctagt
    15061 cttcaaaact agtatgaggg gttaagagcc tcttaggtgg gttcgattcc cacgcattcc
    15121 cgccaatatg taaaaggtat cttttaatta aaagatacct ttttaaattt attttaagat
    15181 aatttatttt taataatata taatgttttg tattatataa tgtaaatttt ctaatacaaa
    15241 acattatata tttagataaa aatctaggag tgtggaaaga tggaaaataa ttttacaacg
    15301 agaactagtt ttctagttgg agatgatggg ataaaaaaac ttaataattc aaatataata
    15361 gtatttggag ttggaggagt tggtagtttt actgttgaag ctttagcaag agctggagta
    15421 ggcaatatta ctattgtaga ttttgatgat gtagatataa ccaatataaa tagacaaata
    15481 ccagccctac attcaactgt aggaagatac aaagttgatg tcatggaaga aagaatatta
    15541 gatataaatc ctaatatcaa tataaaaaaa ataagaagtc tttataataa agatactagt
    15601 gacgaaatac taactgaaag atatgattat gttgtggatg cgatagacat ggtaagttcc
    15661 aaaatacatc taattgaaac ttgtgaaaaa aaaggattga aaataataag ttctatgggt
    15721 atgggaaata aattagaccc aactaaaata gtcgttacag atatacacaa aacaagtact
    15781 tgtcctctag ctaaagttat gaggaaagaa cttagggata gaggtatcaa aaagttaaaa
    15841 gtagtatatt ctactgaaca accaatagaa cttaagaaga aagtaatgaa tggtagaaaa
    15901 gtaacacctg gtagtgtatc atttgtccca tctgtaggag gtttaataat cgcatctgta
    15961 atagtaaatg aactattagg acaataagtt ttaaatattt taatttataa attttatata
    16021 caaatttgaa ggctagaagc atgaatacaa agcaatttta tattcatact tttagcctaa
    16081 ttattttata ttaccttatt ttatgtagtt gtagttttat tttttagatt atgtatctat
    16141 ttcataatta tattttgtaa atataatttc tccatcacta taaaaaacaa tatctcctat
    16201 tctatctgtt ctataaattg atacatggtt ttgttttaga ttattaataa cctccctatg
    16261 tggatgacca tattgatttt tatatccaca tgatattgca gctatatctg gactaatttt
    16321 ttttataaat tctaaagatg aagaagaatt acttccatga tgacctattt ttataaaatt
    16381 aatattattt aatttaaaag aatgtaaaat ttctttttca ttttcttctt cagcatcacc
    16441 cataaataaa aaagaattat cattaaaagt taatttgaaa actatagaat ttaaattaga
    16501 ttcttcttgt atatatgatg gacttaatac atatatattt atattgttat ctatgtttaa
    16561 aacatcattt ttatagagat gctgaataga taagttttta tccgtacaag aatttattag
    16621 attttgataa gccttactat cagttgattg ttcaggcata tatatggagt ttacattaaa
    16681 tttttttata atattatcaa gacttcctat gtggtctgaa tctggatgag ttgctattat
    16741 aatatcaata gtttttattc ttttttgtct aagataacta ataattatat tttcgctatc
    16801 ttcatcacct ccatcaatta atatattctt atttgtgggt gtttgaacta aaatactatc
    16861 accttgtcca acatcaatca tatgtataga tagtagagat tttttgtcac agccgattaa
    16921 aagtgatatt ataataagta ttgataaaaa aattttattt ctcaataaaa aatcactcca
    16981 ttcattacat gtttatataa atttatgatg ggtaatataa gatatatatg acttattata
    17041 ttttatattt taaacaatat aaatgaaatt aataccataa taaaattgga gttttttata
    17101 tatacaaaat aaaattttta aaattaagca ataaaaaagg taggaggatt ttatgttttt
    17161 caaagatatt gaactaaatt caaaaaaaga gttagaccca tattttgatt tagtagatta
    17221 tgaagcttgt gagtactgtt ttagtacttt atatatgtgg caacatgttt ataagacagg
    17281 atattatata ggtgaagatt ttgccgtttt agttggggaa tacgaaggag atagcttctc
    17341 aatattacca cttgctaaaa aagataaact tccagaagtt gtagattttg tccttgaata
    17401 tttttctaaa aataataaaa aaatatactt aagaggtatt actactgaag tagtagagtt
    17461 tttaaaagaa aaatatccag gtagatttga gtatatagaa gaaagagatt tatttgacta
    17521 tatttatgat gcagaaagtt taagaactct agctggtaaa aagaatcaaa agaagagaaa
    17581 ccatataaac tatttcttaa aagagtatgc aggtagatat gaagctaaat tattagataa
    17641 agaaaacttt gatgagtgtt tagtactaat gaaggaatgg gaaagtaata aggaagaaaa
    17701 taatgaattt gatgaaagta tggatgatga attaataggt atcaaaaaga tatttaacca
    17761 ttatgacata ttaaaagata aggtaaaagt gtttggtgtt tatgtagatg gaaaattaga
    17821 agcttttagt ataggagagc ttttaaatcc aaatatggca ttgattcata tagaaaaagc
    17881 taatcccgat ataagaggtc tgtatccatt tataaatcaa caatttttgg taagtgaatt
    17941 taaggacgtt gagtttgtaa atagagaaga agatttaggt attgaaggat taagaaaagc
    18001 taaactttct tatcatcctt gcagatttgt tgaaaagtac agtgttaggg aggcttaata
    18061 gactatatgg agattaggta tgctaaagaa gaagagatag aaagtataaa agatatttgg
    18121 agttattgtt ttaacgatac ggagagtttt atgaagtact attttaatga taaatataaa
    18181 tctgaaaata ctgtagtagc tttagatgaa ggaaaaatta tttcttctct tcagctaaat
    18241 cagtataagt tattactaaa tagcaaggta tataatacat catatgtggt aggagtttct
    18301 acacttccag agggaagagg agctggatat atgaacaaag taatgaaatt tactttaaac
    18361 gaattgtata aaaaagggca attagtttct atattgatgc ctattgacta tagactttat
    18421 agaagatttg gatatgagca ttgttacgac cagattgaat atactattaa cacagatgat
    18481 ttaaaaaatt ttaagtcaag tggaaaaatg ataaagtcta atttatcaca aattgatgat
    18541 ttgatacaaa tagatagaac ttttttaaat gaggttaatg gtaatgtgtt aaaagatgaa
    18601 cattattatg aaaacttatt taaagagatt caaagtgaag atggattttt atacattcat
    18661 gaaggaaatg aaaaagatgg atatatagtt tattttcttc aggaagataa aatgtttgtc
    18721 agagagttat tttataaaaa tatagatgcc cttaaatcaa tgcttaaatt tatatataat
    18781 cacaatactc aatgtaagat agttactata tctactccta caatagataa gataaggttt
    18841 atattagaca accctaaaga tagtgatata aaaataaaac cttttatgat gggaagagtt
    18901 ataaatgtaa agaagtttat tgaagatata gatattgaga aggatattaa tagctcattt
    18961 aatttattaa tagaagacaa gtttatagat gaaaataatg gtctatttaa aatttctata
    19021 cagaataaga aggtatctgt agagcagtta gataaaaaag gtgcagaaaa gcctcaagaa
    19081 gattttgata ttaaattaga tataaatacc ttaacacagt tatcattttc ttatatagat
    19141 gtaaatgaag ctattttctt aaatgatata aaagatgttt cagaagaaac actagaaaca
    19201 cttaattgta ttttttctaa aaaaaataac tatataaatg aatatatata ggtagagtac
    19261 gttaaaagat tctaaaaatc ttttgacgta tttttttgtt tagataacaa tttatcttgt
    19321 ttaaaaattt tctatttgaa aataatctaa ataatatact tttatatggg agtgattata
    19381 attcaaataa gaagaccatt attaattata ttaatgtttg tggtagctat atcatttatc
    19441 attacaaata acacaaaaaa cgacgaagaa cttaatgata agataataac tatacaagga
    19501 gttgtcaaag gaaaaattga aaagaaaaga tacaatcagt acaaggtagg ggtttttcta
    19561 ataaatgatt atacaaaaaa taaaaatttg aagattggtc agaaagttaa tattacaggt
    19621 aaattcaaaa gtttagataa aatgaagtat gatgattttg attatggaag gtatataaaa
    19681 agtactggat ataaaggtat agtgtatata aataactata aaattattga taaaaataaa
    19741 ctttactctt taatagggga aataaagttt tatattagta aaacttatag gtacttatat
    19801 aagaaaaact cagattttat aaattctata ctattagcag aagttgaaaa tttgactgag
    19861 gaacaaaaag aaatttttac cagaactgga actagtcatg taatatctat atcaggtctt
    19921 catacaggaa tattatgtgt aattatatcc tttctattaa gaggtataaa taaattgtat
    19981 aaattattaa tactgtcgat ttttataact ttatattgta taatggtagg tgcgtctcca
    20041 tccataatta ggtctatagc atttgttatg attttttatt tatcaatatt tattgataga
    20101 aagaaagatg gaatatcggc attgtctcta attgggataa ttttaattat gaataacccc
    20161 tatgttatat ataatgtaag ttttcaattg tcttttttag ctacactttc tatattaata
    20221 ttctataata aaataaatag tattataaaa ttaagtatgg tatcattgac aatatcatca
    20281 aatatattaa ctttacctat aatttattat acatttaaag gtataccatt gctttcaatt
    20341 ataggaaatt taattatagt gccatttgtg ggagtaataa tgtatttaag tattgcaagt
    20401 ttaatcgtat ttaaagtaag tgtagtaata gctaaaatta tatctttttt taatagtaca
    20461 tttatagaaa gcatattttt tttactagaa aaaatcagca atttaagttt tgcatacatt
    20521 aatatagaaa atcctaaatt ttatattgtt gttatttatt acataggagt gtttttttac
    20581 atattttaca tagaaggaaa agagataaag gagcaagaga atgaattaca aggatattat
    20641 aaggaatgta aaagagaaaa actttgaaaa aatgtatctt ttttatggaa gagagtatta
    20701 tttaattgag aatgcaataa aagcatttaa agatagtcta aacgagggaa tgcttgattt
    20761 taatttagat ataatagatg ggaaggaaat agtcttaaat cagcttataa gctctataga
    20821 aacacttcca tttatggatg ataggaagat agtaataata aaagactttg aactattaaa
    20881 aggaaagaaa aagaatttta cagatagtga tgagaaatac ttaatagagc atttagacaa
    20941 tattccagac accacaacta tagtttttgt tgtatatgga gatgtagaca aaagaaaatc
    21001 attagttaag aaaataggaa acaatggaat tgtttttgat tgtgataagc tttctgatat
    21061 ggatttgttt aaatggataa aaaaatcttt tgctttaaat gatgttataa tagataattc
    21121 tcaaatcatg tattttattg aacaagaagg atacagagat aagagtagtg aaaagacatt
    21181 atctgattta gaaaatgaaa taaataaaat aagttcattt gttggtaaag ggaataatgt
    21241 aaccaatgat gtaattgata aattatctca aaaaaaagtt gagaatgata tattcaaatt
    21301 aatcgattat attggagaac aaaatgcttc taatgcaatg aaaatattaa atgatatgat
    21361 acaagaaggc gaatctgtat taggtatatt ttctatgata gcaagacaat ttaaaataat
    21421 tatgcaagta agacagttac aacttgatgg atattcaaca aaacttatag ctgataaatt
    21481 aaaaatgcat caatttgttg taggaaaagc attaaagcaa actaaaaatt tttctgatga
    21541 tataattgtg gaaatattaa actatatatt agaaagtgat tacaaaataa agacaggtct
    21601 tataagagat actttagcag ttgaaatgtt ggttagtaga tactgtaaaa gagaagcaat
    21661 ttaaaaaatc tatatattaa taaaaaataa atagcaagat atgttatagt tcagagtaga
    21721 tgtaagctaa attaagtttg atatacaatc aactataata tgtctaacta tttatttttt
    21781 attgtataaa tttacaaaat aaaaaacccc tacatagggg ttattatata taagaaatat
    21841 aaactggtaa ttaagcgttc ataccgttta atttttgagc taatttagct acttttctag
    21901 ctgcagcatt cttatgtata gttcctttag aagctacttg gtatattctt ttttgagcgt
    21961 attggaactt agcaacagca tcctctctgt ttccagctgc aacagcatct tcgaatcttc
    22021 ttattgcagt ttttatttga gattttctaa ctctatttaa agcagttttc ttttcgataa
    22081 cacttattct tttcttagct gattttatat ttgccaccgt gttcacctcc ctgtattttt
    22141 ttatcatatt catcgtcaac atattagatt ttaacagaaa taaatctaaa aatcaaggat
    22201 tattatttat atattttaat aatgtttttt attttgattt tttagactgt aaattgtgta
    22261 taaataattt gcaatatctt gtttttaaat tggtatattt tgtgttttaa atattttgac
    22321 atatataatt aatatttcat tttgtaacaa atatttgaga taatacaaac tattaacata
    22381 cattttgata gtatttccaa taattataag ataatacaag aaattactca tttttgtaaa
    22441 tttaatgaaa aattataaaa atataaattt atatgcttaa ttaagataat ttttccaata
    22501 atcaagataa tttttttcat tagtatgtat gatagatgca tcaaacaata taactaatat
    22561 gttagaaggt tatatgtaat taatgtcagt gtttatatag aatagcattt gtagcattta
    22621 ttatagttgt aattactatt tatatcatag acttgaatag tctaaaaaaa tagactataa
    22681 tatttttata gactaaagaa agggctgata agatggacat agcaaaacta attttaaatc
    22741 ctgcaaggct tcgtatttta caatatattc gactttatgg cagtgttcgt acatctgata
    22801 ttgtaaagta tttaaatgat attcctcgtg caacagttta tcaccatgta aaaattttag
    22861 aagagaacaa tatgattgaa gtaattaaag aaaatcgtgt gcgtggtact attgaaaagg
    22921 tttatgcact aaaggaatat acaacatcta tggaaggaga gaccttcgtt gcactttcta
    22981 cagcatttta tgtaggtctg atgcaggaaa tgaatgaata ctttagcaga aaagagcaag
    23041 accataaaaa ggataatgta tttttctctt cagcattact atatatgagt gataatgaat
    23101 atgaaaatct tcttaaaagt atagctgatt tattgaaacc atatatagaa caaaaaccta
    23161 aatcaaatct aaaacttaga aaactttcaa ttatatcttc tccacctgta gctgataatg
    23221 ataaaacaaa ataacatgca acccattttt ataaaaggag gttatatatg aaatttcatg
    23281 agtttggaaa taaaaacaga ccacatatta tgttgattca tgggggaggg aatgcatggt
    23341 ggaactattt gcgacaagca gaagttttgt ctaacaaata tcatgtgata cttcctacat
    23401 tggatggtca tggagaagaa tatgaaacaa catacatttc tacagaggat acagcagata
    23461 agttgatatc atatatagat gaaaattgca gtggacatct tttcgctttg tgtggggtat
    23521 cacttggtgg tcaaattgtc atggaacttt tatctcgaaa acctaatatt actaaaaaag
    23581 caattattga tggtagtatt tgctacccaa gacctcttat ggcaaggttt tgtattgctg
    23641 gtattcgatt ttttggagga cttttgttta gtgagaaggc ttgtcgcttt caaattgcta
    23701 tgatgccaaa attgttacct gaaaatatgc aatatccaga tgaaataaaa gcgtattata
    23761 tgacagatat gccacatgta agaaaagaaa cattctataa tatgtatcgt acttacatga
    23821 tgaactatac acttaaagag aatgttaaaa aaaccacagc acaagtaatg tactggtatg
    23881 gagaaaaaga aatgaagtgt gtcaaaaaat ctgcaaaact gtttcagtct tatgtgccct
    23941 cttgtgagat ttatgaagct aagagctata atcatgggta tttatcactt tatcttccaa
    24001 atgaatggtt ggaaattgca gaaccatttt tccaaaagga ataaaggtgt taggtgatta
    24061 ttgtataatt attgctgttt ttttatatag taaataaatt aggtataaat ataaaaaatt
    24121 attttagtta atatattagt gaaagcttaa taggaaaatt ataaatagat taaaggtagc
    24181 acctatataa atagttgcta cctttttctg tttgtaaata aatgatagat aagaaggttt
    24241 actgacaaat cactgactaa acccaatttt cttacattga aagccttaat tttacttgtt
    24301 ttaaataaat ttacaatttc ttgttataaa atactaaatt ttgttaacaa ttataattag
    24361 catttaattt atactggagg tttatatgat tagtgtaaga acagatttag ctttagaagc
    24421 tagtgaaatg tgtgaaaagt ctcaagaagg aagtagtatt cctggtgtaa aaatagaaac
    24481 taaagaatta gaaaattgca ttgtaactaa agttgaagta atagacaggc aaggcgcaga
    24541 gataatgaat aaagatatag gaaagtatat aactctggaa agtaatctta tgaagtttga
    24601 tgatgatgag tcaagagaag aaatgataag ttatttaaaa gaggagttag tagatatatt
    24661 tggccaagac aaaaataaaa aaaccctggt aattggtctt ggaaatagaa atattacttc
    24721 tgatgcgtta ggaccaaaga gtgtatcaaa aacacttgta actagacatc tttttaaaaa
    24781 ttataataaa gactatgatg atgatttcac tgaggtatca gctttaagcc caggagttat
    24841 gggtgttact ggaatagaaa ctagtgaaat agtaaaatca ttggttgaga aggttaagcc
    24901 agatagagta gtagcaatag atgcattggc ttcaagaaaa atggagagag taaactctac
    24961 tatacagata tcaacagcag gaatatcacc tggtggaggt gttggcaata ctagaaaatc
    25021 tctaactaaa gaaactttag gcgtggatgt tattgcaata ggcgttccaa cggtggttga
    25081 tgcagcaact cttacaatag atgtcttaga tatggcaata gacaatttaa tagctcaatc
    25141 agaagaaaca gaaagttttt atgaaatgtt gaaaaaactt aaagaagaag aaaaatatca
    25201 tctaataaaa gattcgttag acccatatga caagaactta atagtaacac caaaggatat
    25261 agatgataca atcgaaaatc tatctataat aataagtgaa ggcttaaata ggtctttaca
    25321 tccaggtaga ttggtataaa ataaggagga gcaattatgt ttaaaaaatg cattaaagta
    25381 gtaaccttga cttttatatt agtatgcatt ttaccaggaa aatcattagc tttgaatcaa
    25441 gatgattttt taaagttttt agtaaattca tcttatccag aagctaaagt cgaaggaaat
    25501 gatacagaaa ataaaaagaa taataaaaat aaagaaacaa gtaaggaaaa taaggaagaa
    25561 agtaaagaag gaaacactaa atctaaagat gcaagtaaag ttgataataa aaaagagagt
    25621 gaaaaagaat atataaaact ttatgttggt aaagaaaatg ttccagatat tgagtcaaaa
    25681 aattcagaca caactgaaac taacacaaca tctagttcag attataagga tgatttaaga
    25741 gtaaccaaag aaaatccaag aattttgata tatcatactc atggatgtga gacttattca
    25801 aattcacctg atggaaatta tcattcaaga gataagaaaa attcagtaat ggaagtagga
    25861 agtgcattaa ctagtgcttt agatagcaaa ggatggggtg tagtccatac tactaaatac
    25921 catgactatc catcttataa taactcttat gcaagtagct taaaaacaat acaaagtata
    25981 ttacctaaat ataactcagt ggatatagcg atagacttac atagagatgc tagggattta
    26041 actaatccag ccactaagga aaaagaccat ttaaaatata caactatgat aaatggagag
    26101 agagtatcaa agttcttctt tgttgtagga ggtaaaaata caaatagaaa acaacttaga
    26161 gctttagcag aagatataac tgcttttgct gagaaaaagt atcctggtct agtatctcca
    26221 atagtagaaa aagactatgc tagattcaat cagtttgcag ttaagaatca tatgttagta
    26281 gaaataggga ataacgcaac aagtgtagaa gaatctaagg ctactacaaa gtatttagcc
    26341 gagattttgg atgaatattt taaacaaaaa aattagagct ttaagttata attaggagca
    26401 tgctaaatga gccgattaga aaaaaatata gaaagtaaaa gtaaactaag aaaatacaag
    26461 tatattatga gaatcttatt tttgattact atgattatat gtacatcagt ttgtgtattt
    26521 atagtggaca gtaatgcaaa aagtatgcta ggaatgaaac aatatgattt tccaagtatt
    26581 aaatttgata taacaaaatt tgattttgac ataccaaatt ttgatataca tgaaatcata
    26641 aaaaaattta ataagtagta ataagtgaat aaggtttatt gattaaaata agccttattt
    26701 tagttatata tttttaatgt ataaaataaa aattcattaa ctgtatttta taggatttac
    26761 tttaagttta tgatattata taatatttag tgttagactt gataatccac atataatgtg
    26821 gataattttg tttagtgcca attagtttat attcaaaaat tttaaatttg gtatataaag
    26881 agtttttaga taatgtaaaa taataactat aagaataatc aagaggaggg aattttaagg
    26941 tggacaataa acaaagtaga actagaaatt ttagtataat tgcacatata gaccatggaa
    27001 agtctacctt agctgataga ttaatacaac aaactgggct tgttagtgaa agagacatga
    27061 aaagtcaatt acttgacaat atggaccttg aaagagaaag aggaatcact ataaagcttc
    27121 aaaacataag attaatgtat aaagcgaagg atggaaatga atattattta aatcttatag
    27181 atacacctgg acatgtagac tttaactatg aggtatcaag aagtttagct gcatgtgaag
    27241 gagcactatt agtagttgat gcagctcaag gtgttgaggc acaaacttta gccaatgttt
    27301 atcttgctat agaccaagat ttagaaatat taccaataat aaataaaata gatttaccaa
    27361 gtgcaagacc agaggaagta aaaaatgaaa tagaagattt aatagggctt gattcaagtg
    27421 aagctcctct tatttcagct aaaactggtt taaacataga agatgtttta gaagatattg
    27481 taaaaaatgt tcctccacct aaaggagata atgaagctcc attaaaggca ttaatattcg
    27541 attcttacta tgatgcttac aaaggtgttg tagcttatgt tagagtattt gaaggaactg
    27601 ttaaaaaggg tatgacaata aaaatgatga ataccaataa aaagtttgag gtaactgaag
    27661 ttggtgttat ggctccaggt caaactgaac ttagtgaatt atcagcaggt gatgttggtt
    27721 atattgctgc tagtataaaa gatataagaa gttgtcgtgt tggtgataca ataacagatt
    27781 caaataatcc tacagaagaa cctttaccag gatacaaaaa agctactcca atggtatatt
    27841 gtggtatata tccaggagaa ggagaaaagt atgagaatgt tagagatgct cttgaaaagc
    27901 ttcaagtaaa tgatgctgca cttgaatatg aagctgagac ttcagcagca ctaggatttg
    27961 gttttagatg tggtttctta ggtcttttac atatggagat aatgcaagaa agacttgaga
    28021 gagaatttaa ccttgatata attactacag ctccatctgt tatatataga gttacaaaaa
    28081 tggatggaga ggttgtaatg atacaaaatc ctgcaaactt accagaacca tctgagataa
    28141 agatgataga agagcctata gtaaaaggag atataatagt tcctaaagac tatgtgggtg
    28201 ttgttatgga gctttgccag gaaagacgtg gaaatatgtt aaatatggaa tatatagatg
    28261 atagaagagt aatgcttcac tatgaccttc ctctcaatga agttgtttac gatttctttg
    28321 atgctttaaa atcaagaact agaggttatg gttctcttga ttatgaggtt aaaggttatg
    28381 tagcatctac acttgtaaaa cttgatatat taatcaataa agagcaagtg gatgcactta
    28441 gttttattgt ccatgagaca cgtgctttcc ctagaggaaa ggcaatgtgt gagaaattaa
    28501 aaggagaaat tccaagacat cagtttgcta taccaataca agctgctgtt ggtaataagg
    28561 ttattgcaag agaaacaata agcgctctaa gaaaagatgt tcttgctaaa tgttatggtg
    28621 gagatatatc tcgtaagaag aaacttcttg aaaaacaaaa agaaggtaag aagcgtatga
    28681 gacaaattgg ttctgttgaa gttcctcaaa aagcatttat gtctgtgctt aaattagatg
    28741 agtaaatcct tataaattta gataaagata tttaaaagct agagtgattt tagaattatt
    28801 tctaaattag tctagctttt ttatggtata ttttaagtaa actcatagag aatataagta
    28861 agaatattaa agaagaataa aaaggtgata tttatgatta atatagaaat tcctaaaaaa
    28921 gtagactata taattaaaga attagaaaag aatggttatg aagcttatat agttggagga
    28981 tgtgttagag attgtttatt agaaagagtt ccaaacgatt gggatataac aactagtgct
    29041 agaccagaag tggtagtaga attatttgaa aaaacaattc caactggtat acaacatggg
    29101 actgtaacag ttatgattga acatgaacca tttgaagtga cgacttatag aattgatgga
    29161 aattatagtg atggtagaca tccagattca atagaattta caaataacat agttaaggac
    29221 ttgtcaagaa gagattttac tatcaattca attgcataca attcaaagac aggattagtc
    29281 gacccattta atggctatga agatatacaa aataagtata tacgttgtgt tggaaatcca
    29341 gtagatagat ttgaagaaga tgcacttaga atgcttagag cagttagatt ttcagcacaa
    29401 ctcaatttta aaatagctga aggtactaag caaagtattc ataaaaaagc agatttgata
    29461 aaaaatgttt ctattgaaag aatccagaca gagtttaata aaatattagt atctgattca
    29521 tctaaattaa acttattaaa atcaacaggt ttgttgaaat ttataattcc tgaaatatgt
    29581 gaattagaag atgttactca acacaatcca tatcacatct atgatgtaca aaaacatact
    29641 ttaatagcta cagaagtaat tgaagatgaa ctgtatttaa aacttacaat gttgtttcat
    29701 gatttaggta aaaaagtaac taaaacaact gataaaaatg gtgttgacca tttttatact
    29761 catagtagag aatctgtaaa gattgcaaag aagattttga aaagacttaa gtatgataat
    29821 tatactatta ataaagtttt aatattaata caatatcatg attatagaat agaacctaaa
    29881 aggaagataa ttaaaaagtt attaaataaa cttgaagatg ttgaattatt tgaagattta
    29941 ataaaagtta attgggctga tacacttgca aaaaatccaa agtatgcaaa acaaaagata
    30001 ttaaatctta ttgagtgtga aaaagaattt aaacatataa taaatcaaaa ggagtgcttt
    30061 aatcttaaag atttagctat taatggaaaa gatttgatat ctataggtat aaaaccaggt
    30121 aaagatatag gatatatttt aaataagatg cttgaaatag tcataaataa tccagagtta
    30181 aatgaaaaag aaatactaaa agaaaaagca ttaaatatat atacatttta gattcaaata
    30241 taaaaaattt aattacttta aaaaacatag aataaaatac ttatttagat aaaataaata
    30301 atttttagag aatattttag aagttacgat tgtatgattt ttaaatgcat aggcatttac
    30361 tctaggacta tagactaata taaaaaaaaa ctttgggaat actaaaacca taaatttata
    30421 aaattaatat tttatatact gtaaaacagt gaggagggac agtatgcata ctcaactaca
    30481 aaagactatt ggtctttcag cagctctttc tactgttgta ggtatggtta taggttcggg
    30541 agtttttttt aagccacaag caatatacac tacaactaat ggagctccag gtctaggtat
    30601 tatagcgtgg cttttaggtg gttttataac aataactgct gggcttacag ctacagaaat
    30661 ttcagctgct ataccaaaaa ctggtggtat gatgatttat atcgaagaaa tatatggaga
    30721 aaagttaggt tttttaactg gatggatgca aactgtatta tttttcccag gtacatcagc
    30781 ggcattagga gtaatatttg ctcaacaagc atctgaactt ttaggaatga gcccaaataa
    30841 tatggcaaat gtacttccta tagcaattgg agttatacta tttttagcgt tattaaatat
    30901 aataggttca tccttaggag gaaaagttca gacagtagcc actattggaa agatgatacc
    30961 tttaatttta ataatagtct ttggatttat taaaggtcaa agtagtgaag tattaaatcc
    31021 atttgtagga gatggtgtaa atgcatcaaa tgcacttgga caagtattaa tagctacttt
    31081 gtttgcatat gatggttgga taaatgttgg agctatatca ggagaaatga agtctccaga
    31141 gaaagattta ccaagagcaa tagttggtgg tttatcatta gttatggcag tttatattat
    31201 aataaatata gcttatcttt gggtagtacc agcaagtgaa ttagcaacag ttacttcccc
    31261 agctacatta gtagcaacaa gattgtttgg aaatataggt ggaaaagtaa taactgtggg
    31321 tatattaata tcagtatttg ggacattgaa tggatattta ttaacaggtt caaggatacc
    31381 ttatacatta gctgaaatgg gaactttacc agcatctaaa actcttttaa aagtaaattc
    31441 tggaggttct cctgtaaatt caatactact tataactgtg ttagcctgtg tatatgcatt
    31501 atctggtcaa tttaatcttt tgacagactt aacaatattt tcaatatggg tattttatgt
    31561 attgactttt ataggtgtta tgaggcttag aagacaaaag ccagatttac acagaccata
    31621 taaagtccct ttatatccaa taataccaat tatagctata ttaggtggac tgtttgtaat
    31681 aataaatcaa atattgactt caacagtcat atctttaggc ggaatattta taacactatt
    31741 aggtttacca gtttattatt atatgaaaaa aagataacta cttaatttaa gttagataaa
    31801 tttgggtaaa ggtgaaaatt aacttttatc caaatttttt atactgttat acaatataag
    31861 tattatatat tgcttgatgt gctattttgt ttgatttata atttagtaat tgatgtttta
    31921 agataattta agaaatgagg agtgaaagat gctaggactt tatgtacata ttccattttg
    31981 tgtgaaaaaa tgtaagtatt gtgattttaa ttcttataaa atggacatag attcaaaaaa
    32041 aagatatata gaagacttaa aaatagaaat ggaattatat agtaataaat tatataaaga
    32101 taataaatat aaaaataaag aatgctgtag tctaaataaa aatgacaaaa taacgagtat
    32161 atttgtaggg ggaggtacac ctagtatact aacctctgat gaaataagag aagtatttat
    32221 aagtataaaa gaaatgtttg atatagatga gaatgcagaa ataactatag agtgtaatcc
    32281 tgggacatta acattagaaa aattaaaaac tatgaaagag attggcataa atagacttag
    32341 tatagggcta caagctattc aagaaaagca tttgaacttt ataggaagaa tacatactta
    32401 tgaagaattt gagaaaaact ataaagatgc attaagtgta ggttttaaaa atattaatat
    32461 agatttaatg tacagtcttc caaatcaaac tctatgtgat tggaaggaaa ctcttgaaaa
    32521 agttgtacac ttaaatccaa cacatatatc agcttattcc cttatactag aagaaggaac
    32581 tgaactatac aatatgtatg aaagtaataa atttgaactt atagatgaaa atgtagatat
    32641 agaaatgtat gagtatacaa taaactactt aaagtcaaaa ggatataatc aatatgaaat
    32701 atccaactac tcaaaagaag gctataattg tgagcataat attttatatt gggaatgtga
    32761 acattatata gggattggag caggagcttc tggctatatt aatgagaaca gatacaataa
    32821 tgtagaatct ttagaagatt atcatttaag tttggtaaaa agagaaaaac caatacaaga
    32881 aaatgaaatt ctttctgaga aagatatgat agaagaaaag atatttatgg ggcttagaat
    32941 gaataaaggc ataaaatttg aagattttaa aaaaaaattt ggaatagatt ttagagagaa
    33001 gtataataag caaatagaaa tgctattagc tagaaagctt ataaatcaga gctttgaagg
    33061 tatacaatta actcaaaaag gaagagaaat atctaatagt gtatttatag aatttatgga
    33121 ataattttta aggtgttgac aaaataaatt tataatggta tataatatat ataatctttt
    33181 tagcactcga acttagtgag tgctaacagc taggaggtat aataatatgg aattaaatga
    33241 aagaaaatta aatatcctca aagctatagt taaagattat atagaaacag ctgaagctat
    33301 aggttctaga acaatatcta aaagacatga tttaggtgtt agtgctgcta ccataagaaa
    33361 tgaaatggct gaccttgaag aattagggta tttaattcag cctcatactt ctgcgggtag
    33421 agttccatct gaaaaaggct ataagttata tgtaaactct cttatgagta aaagcgaatt
    33481 ggatgataat gataagattc ttattgaaca atgtatgaat cacaatataa atcatataaa
    33541 agaattgatt catgaaactt ctaagctatt atcgcaacta acaaactata caactgtagc
    33601 agttactaag agtttaataa atcaaagtgt tataaagcac atacagttgg ttgctatgaa
    33661 tgacaataat attttactta tagttgtaac agataaaggg gacttaaaaa aagctaacct
    33721 tacaactaat gtatatttag atcaatctaa gttaaatttg atttctgata atcttacaag
    33781 gaagctctta ggtaaaagta taacagattt ggatgataat ctaattgctt ttattaaata
    33841 cgaaataagt gagtattctg ggcttataga tgagctttta aatgctttga actcaaatat
    33901 gaaagaagaa gatttttctc tatcattaaa tggagctact aacatattta gttatccaga
    33961 atttaatgat gtattaaaag caaagtcatt tttaaatatg ttggaaaaaa aggaaacaat
    34021 agctgacata attaaatcaa agggaataca aaaagacaat ctaaatataa taattggtag
    34081 tgataatgat tgtgaactgg cacaggattg tagtatagtt acagcaactt ataatgtaga
    34141 tagagacttg gttgggcgaa taagctttat aggccctacc agaatggatt atgctagaat
    34201 ttactctata ataaattata tgagtttatt aattaataga aagtaaagaa attttaaatt
    34261 gcgaggtgta aagtcttgga taaaaaaaat gagcaacagg aagtaagaga agaaaatgat
    34321 acttctatta accaagaatc ggaaactcaa gtagagttag aagaggaagt tgttaatgaa
    34381 gaatgtgaaa catcaagtga aaaaactgat gaaaaagaag ttgatgatga aaatgtaaca
    34441 gatataaatt ctaagttagc agaaaaaaaa ttgcaggatg agttggatga attaaatgat
    34501 aaatatcaaa gacttcaagc cgaatatgca aactacagaa gaagaactca acaagagaaa
    34561 gagacaatag gcgtatttgc aaatgaaaaa ataataactg aattgatacc agttatagat
    34621 agtatggaaa gagccttaga tgcatgtgaa gataaggaag atactatgta taagggtata
    34681 agccttgtac ataaacaatt aatagacact ttagtaaaat ttggagtaga agaaatagaa
    34741 gcagaatcta aggaatttga ccctaatcta catctagcag ttatgcaaga aagtgtagat
    34801 ggagttgaag caaatcaaat agtaatggta cttcaaaaag gatataagct aggaactaaa
    34861 gttgtaagac cttcaatggt taaagtttct tgctaagtat aaattaaagg ttaaattatt
    34921 taacctaata taaaatatta aaataagtaa aacttaatta tataattact cgaggaggat
    34981 tttagtcatg ggaaaaataa taggaataga tttaggaaca acaaattcat gtgttgcagt
    35041 gttagaaggt ggagaagcac aaataatagc aaatagtgaa ggtatgagaa ctactccatc
    35101 agtagtagca tttacaaaag atggtgaaag aatagttgga gaacctgcaa aaagacaagc
    35161 agttacaaat gcagataaaa caataacttc tataaaaact catatgggaa ctgattataa
    35221 agtaaatata gatggaaaat catatactcc acaagaaata tcagcaataa tattacaaaa
    35281 attaaaatca gatgcagaaa gttacttagg acaaacagta acagaagcag ttataacagt
    35341 accagcttac tttacagatg ctcaaagaca agcaactaaa gatgctggta gaatagcagg
    35401 gcttgatgtt aagagaataa taaatgagcc aacagcagca gctcttgctt atggtatgga
    35461 taaattagac caagaaaaga aaatattagt atttgactta ggtggaggaa cttttgacgt
    35521 atctatactt gaaataggag atggaacttt tgaagtttta gctacagctg gtaacaatag
    35581 attaggtgga gatgactttg accaaatagt aatagattat ttagcagagg aatttaaaaa
    35641 agctgaaggt gtagatttaa gaaatgataa aatggctctt caaagattaa aagaagcagc
    35701 agaaaaggct aagaaagaat tatcatcaac aatgagttca aacataaact tacctttcat
    35761 aactgctaca gcagaaggac caaaacactt aaatatagat ttatcaagag ctaaatttga
    35821 agaattaact agaggtttag ttgaaaaaac tatggaacca actaagacag ctttacaaga
    35881 tgcaggactt tctacaggtg atatagatga tgtattatta gtaggtggtt ctacaagaat
    35941 accagcagta caagaagctg ttaagaagtt tataggaaaa gaacctcata aaggtataaa
    36001 cccagatgag tgtgttgcag caggtgcttc tatacaagct ggagttttag caggggatgt
    36061 taaagactta ttattactag atgttactcc attatctctt ggtatagaaa ctatgggtaa
    36121 tgtaatgact aagataatag aaagaaatac tacaatacca actaagaagt ctcaaatatt
    36181 ctcaactgct gctgataacc aaacagctgt tgatatacat gttcttcaag gtgaaagaag
    36241 tatggcttat gacaatacaa ctttaggaag attccaatta acagatatac caccagcaca
    36301 aagaggaata cctcaaatag aagttacttt tgatatagat gcaaatggta tagttaatgt
    36361 ttcagctaaa gatttaggta caggaaaaga gcaaaaaata actataacat caaacactaa
    36421 tttatcagaa tcagaaatag agcaaaagat aaaagaagca gaaatgaatg cagaagctga
    36481 caaacaaaag aaagaaaaaa tagaagcatt caatcaagct gaatctacta tatatcaaac
    36541 tgaaaaaact ttaaatgaac ttggagataa aataagttca ggtgaaaaag aggatataga
    36601 aaaagctata gcagacttaa aagctgtaaa agataatcaa gatgctacag cagaagaact
    36661 taagaaagct acagatgaag taatgactaa gttccaaaaa gtatctcaag aaatgtacca
    36721 aaaagcagct caagaacaac aagcggcaca aggtgcagaa caagcacaag acaatggacc
    36781 taaagatgac aatgtagtag atgctgactt taaagaagta gatgaagata aataagctat
    36841 ataatatgta acactaaatg ataattggaa catatatgat ttgtgaaaat catatagatg
    36901 ttaaagatat atggacaata tacatcataa agaatataat atatcataga ttatataact
    36961 taaagtagaa tataagaatt aatgatagct tgtagtttat tattctacaa gctatcgttt
    37021 tgtaaaatga aggtggtgtc aatttttgag tacaaaaagg gattattatg aagtcttagg
    37081 tatcagtaaa ggtgcagaag ctcaagagat aaaaaaagct tatagaaaat tagcaatgaa
    37141 gtaccatcca gatagaaatc ctggagataa agaggcggaa gaaaaattta aagagataaa
    37201 tgaagcttat gaagttctat ctgatgatac aaagagaaaa acttatgacc agtttggaca
    37261 tgatgggcta aatggtcaag gcggttttgg tggtcaagga ggatttggcg gtcaaggctt
    37321 tggtggtttt gaagatatgt tcggagatat atttggtgac atgtttggag gaagcttcgg
    37381 aggtggaaga gcaagaagaa gagggcctca acgtggtgca gatataagac agagtgttac
    37441 tatatctttt gaagaagctg catttggtaa aaagatgtct ataaaagtaa atagaagtga
    37501 agaatgtgaa gaatgtaatg gaactggagc aaaaccagga acatcaaaga aaacttgttc
    37561 aacttgtaat ggaactggtc aagttagaac tgttcaaaga actccatttg gtaatatagc
    37621 aagttcaaga ccatgtagtg cttgtaatgg aactggagaa gtgattgaat ctccatgtag
    37681 taaatgtcat ggaactggaa atacaagaaa agttaagact atagaagtag atatacctgc
    37741 tggtatagat gatggtcaaa tgataaaact ttctggtcaa ggtgaagtag gagaaaaagg
    37801 tgctccaaga ggagacttat atattgtagt taatgttaag tcacatccac tatttactag
    37861 agatggaaat gatatttatt ttgaaatgcc aattacattt gttcaagcaa ctttaggtga
    37921 tgagatagaa gtacctactt tggatggaaa agttaaatat agtgtgccag aggggacaca
    37981 aactggaact gtatttagac ttaaagagaa aggaatccct agaattagag gtaattcaag
    38041 aggagaccaa tatgttaagg ttgtagttga aattcctaaa aaattaaacg ataagcaaaa
    38101 agaactattg agagaatttg cgaaggagtg tgggtcgaac gtccacgaaa agaagaaaac
    38161 cttcggacaa aagatagaag atatgtttaa gaaaaagtag ttaaagtagc caatatataa
    38221 tcatattttt aaaatcttag ttatttataa gattgtcaaa ggagatatta tgatttttat
    38281 attggctatt tttgtataaa aaataaatgt gcataaaata aaactgaata taaataattt
    38341 tctgaaaaat acttgtccta aaatatataa tatgctataa tataatcaaa taaaagaaag
    38401 gggtgattcc agtgggaacg gatgtggcac tgccaaatga tgaagaaaac tttattgtaa
    38461 tatacaaaat aaaattagat acttttagtg ctagattaag tactggaaaa actcatgagc
    38521 tgggataatt attgtaatta cctagactca aacttttagt agtaaaatag taatattata
    38581 tagacaaggt atctaatttt taaatctttt gtatgaatta aaatttttat aaagggtata
    38641 tctgattaga atgtaattag ggaaacctag ttgtgaatta cttttagtat atacatgtgt
    38701 aaagaaatat gtatatggta ttgggtattg tgctagatgt gtatgtaaag gaatatgtgt
    38761 ctagttgggt atatgtaaag aaatatactt ataatctatg aaaaattttt agtataaatt
    38821 gctaaaacat tgagattgtt ttttatagaa agttagttta taccaactaa aaatgtgctt
    38881 aagatttgtt tgatgtttaa ttataaataa ggttgtagat aaaaaaataa gtaaagacaa
    38941 aggtttaaaa tacttgcttt aaatatagtt tgttttgaac acttgccaaa ttaaaataat
    39001 taataaaata gacatcttct catagtaaaa tatactgtga gaggatgttt ttgctttgtt
    39061 cataaacttt tatgaaaaat ttgcatagtg tcacatttta atatactata tatataataa
    39121 aatatagata aaattaaatg attcaaaaga gaaaggtgaa aagagatgta ttatataggt
    39181 gtagacatag gaggaacagg tatacaagca ggagtagttg ataactatgg gaagataatt
    39241 tttaggtcag agtgtaaaac agtaattgaa aaaggatttg aaggaatact taatgacata
    39301 aaaataatga tttataagtt gttggaagat aataaactta ctatgagtga cataaaatct
    39361 attggatttg gtgttccagg ttttataaat aaagaaggat tagtaacttg tgtaaattta
    39421 aaatggaata aaaaagcttt taataaagag ttaaaaaaaa gatttccaga tgttgaaatt
    39481 catggagaaa atgatgcaac agtagcagca cttggagaag caaagtttgg aagtatgaaa
    39541 ggtgctaatg ttggagtatt atatacttta ggaactggtg taggtggagg aatagtaatt
    39601 aatcaaaaag tcttttctgg agcacatgga ttgggttcag aaataggtca tcaaattata
    39661 ggagaaaact attttaattg taattgtgga aataatggtt gtgtagaaac tttttgttca
    39721 gcaactgcaa ttataaagta ttctcaaaaa ctgatagaag aaggagaaaa gagtaggatt
    39781 ttagatttgg cagagggaaa tttagaaaat gtaaatgcaa agatggtgtt tgatgcatat
    39841 agagaaaatg atttagtggc aattaaagta ataaatagat ttaaagagta tttagcaaaa
    39901 acttttgcaa acacaataaa ttctttagac ccagaaatta tatctatagg aggaggcatt
    39961 tctaaatcta gcgatataat acttgatgga atagaaggtt tggtaagaaa atttgtatta
    40021 tacaaaacag aagatatagc tacaattaca tgtgcaactt taggttcaga cgcaggaatt
    40081 ataggagcag cttttttata atgtaaatga actgcttatt ggaggcgtga tgatatatgg
    40141 gtaaaacaaa tgctagaaga acgctttttt tgatagcaat aggttcagga actatgctga
    40201 atcctcttaa ttcttctatg atttcacttg ctttacatag tatacaaaat gattttcata
    40261 ttagttttac aactgtatct tggattgttt cagcatttta cctagctagt gctattgcac
    40321 aaccagtttc aggtaagata ggagatttaa taggtagaaa ggtcttattt ttgagtggtt
    40381 tgatgcttgt aattttatca gcatccatag taccacttgt tcaatcattc tttatattga
    40441 tttttataag agtaattcaa gcaattggaa caagtaccct atatccatct ggagttgctc
    40501 ttatacaaaa taatataaaa gaaagacaat cttctgcatt agcagttcta accatttttg
    40561 cttcaactac agcaggatta ggtccgacac ttggaggatt attgttggac ttaggaggat
    40621 ggcatgctat atttcttgta aatatacctg ttgttttggt ttctatatgc ttagggtatt
    40681 ttttattccc aaaagaagta aaagaaaaga aatctataaa agaaacttta aaaaatgttt
    40741 tgtcaagatt agatattatt ggcatacttc tattttcaat tgcaatgatt tttatattac
    40801 tatttttgct atctatgaag gaatctttta acttagaaca acttgtattt ggtataatac
    40861 tgatgtgtct ttttatttgg catgaattga gaacaaaatt gccatttata gatattaagc
    40921 tttttgtaag taatcctaaa ttgtcaaaag tttacttgca atttattata ttaaatttct
    40981 ttaattatat tttgtttttt ggtcttccta gttattttca agatgcctta cattatagtg
    41041 caaagtcgac tggattattt atgctattta tgtctggtat aggtatattt atatctccat
    41101 taactggaaa atggatagat aaatctggaa ctagatttcc tcttgttaca tcatcaatct
    41161 ttatgtttat tagtgcagta cttctttcag tagtttttat ccatatacct gtaataggaa
    41221 agggtattat attatcatta gcaggtatta gttatggagt tggtaatgta gccctgcaat
    41281 cctctatgtt tgaagaaagt cctcgtgaca gtatagggac agcttctggt ctgtttcaaa
    41341 ctagtcgtta tttaggttct attttagcaa ctgttttact tggaatggta tttgaagtaa
    41401 atataacatc agaacaattt cagatattag gttatgttat ggtggtctta ggtacaataa
    41461 gttttttatt aaattttata ttaaagaaag aattaagaaa agtagaatag tggatttatg
    41521 gatttaataa gtctaataac tgataagttt aaaaatattg tttgtaaaac ataactggtt
    41581 tgatatttat taattctaag ttttgaagca tagagtactc gataagtata caatattttg
    41641 aattaaaatt aagcagaaat ttgaactagt ctttcaaatc tctgcttaat ttagtagtta
    41701 aattttttta tagagaaaat aagatttgac acttagataa aaaatcattg cattttcaaa
    41761 attctttaaa tcaaacccaa gtatctcatt aatct
//
LOCUS       DAEPKC010000023        41765 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.023, whole genome shotgun sequence.
ACCESSION   DAEPKC010000023 DAEPKC010000000
VERSION     DAEPKC010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 41765)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41765)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41765
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.023"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            369..3023
                     /gene="adhE"
                     /locus_tag="KR294_001330"
                     /gene_synonym="adhC"
     CDS             369..3023
                     /gene="adhE"
                     /locus_tag="KR294_001330"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HBH0239412.1"
                     /translation="MAHKEQVIIENKKENEVMSVGLDTVNNVESLVKKLAKIREAQKI
                     FATYSQEQVDKIFLAASLAANKQRVPLAIMAQKETGMGIAEDKVIKNHYASEYIYNAY
                     KETKTCGVIEKDEAFGMTKIAEPIGVIAAVVPTTNPTSTAIFKALLALKTRNGIIFSP
                     HPRAKNSTIEAAKVVLEAAVLAGAPEGIIGWIDEPSLELTTTVMKEVDLTLATGGPGM
                     VKSAYSSGKPAIGVGAGNTPAIIDDSADIKTAVNSILVSKTFDNGMICASEQSVIVLE
                     NIYNEVKKEFKERGAYLLDKDETEKIRNIILVNGGLNSKIVGQTACTIAKLAGFEVPV
                     DTKVLIGEVESVEIEEAFAHEKLSPVLAMYKASDFDDAVRKAEKLVEDGGFGHTSSLY
                     IDDVNQREKLDKFTSAMKTCRILINTPSSQGGIGDLYNFKLAPSLTLGCGSWGGNSVS
                     ENVGVKHLLNIKTVAERRENMLWFRAPEKVYFKKGCLGVALKELKDVMNKKRAFIVTD
                     TFLYNNGYTKAVTDLLDEMNIKYTTFFEVEPDPTLECAKIGAKAMREFNPDVIISIGG
                     GSAMDAGKIMWTLYEHPDVDFQDLAMRFMDIRKRVYTFPKMGEKANFVAIPTSAGTGS
                     EVTPFAVITDQDTGVKYPLADYELMPNMAIVDSDMMMNMPKSLTSASGIDALTHALEA
                     YVSMLATDYTNGLALQAIKSIFEYLPRAYDNGAKDPEAREKMANASTMAGMAFANAFL
                     GVCHSMAHKLGAFHHVPHGVANALLITEVMKFNSSDAPKKMGAFSQYKYPEALKRYAE
                     IASFLGLKGNSDEEKFQSLLVAIEDLKLKVGIPKSIKEFGVEESKFMDSIDEMVIQAF
                     DDQCTGANPRYPLMNEIKDMYLNSYYGR"
     gene            3299..5518
                     /locus_tag="KR294_001331"
     CDS             3299..5518
                     /locus_tag="KR294_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBH0239413.1"
                     /translation="MTGRNKSFTLITILFLTSLFLTMGYIYIEDTKHLLMSEAKIHIK
                     EVAVQGSQLAQRQIEKDLDVLNIFSNYYASNPDIPNEEKMKNLLDEMENQKFYTMAIV
                     DINGNAENTKGDKFSVKDREFFKNSIKGKKYVSSPYVDEVNKSIKKIAISVPLLNNDK
                     VVGVLYCTYNINTLMKLINISFYENNSISYVVKNDGTIILHPQGDSLSKNIYKLLEQD
                     NDIQEVNRLKKELQENKTGATVLNMLEERRYLGYATMDNGNSENNYIKDWNLIFSIPE
                     TVVFSNSKQIINRAVYAVLSIVLIFVAIIFYIIYIKKSNEKEILSLAYEDKVTYIGNQ
                     NKFYRECSKYLLDKPSLNYIIVYFDINNFKMINDTFGYEFGDNLLITIAKALKEELTE
                     GEVYARLSSDYFAIFCDYKNGRNKIIRKLDNIRSNIESNLSIVFEISLCVGIYFVEEG
                     EVDIQKAVNKANMARSVAKGKNINYAIYNEDVRNKLSEESMILDDIKIALVKNQFEVY
                     YQPKFSLVTGEMIGSEALIRWNHPEHGFISPAVFIPIAEKSKLILKIGRFVFERVCND
                     LYEWKKQGKKIVPVSVNLSRVELYQPDIVKFINKTIKMYNLSSDFIEIEITETVAINE
                     LNILKNVLNELRTYGFSISMDDFGTGYSSISCLRDMPIDILKLDKSFLGGIEHDERSR
                     NIAKSIVSLAKSLDLVVIIEGVESKEQAELMKQFGCDLVQGFYFARPMPAKNFLDLL"
     gene            5772..6434
                     /locus_tag="KR294_001332"
     CDS             5772..6434
                     /locus_tag="KR294_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-binding protein"
                     /protein_id="HBH0239414.1"
                     /translation="MIDISIDDKLKERWPNAKLGCIQAKVAVNKSSEKLINEINEFCD
                     TINQSLKVEDITKLDKIKDARNAYKELGKNPSRYRTSSEALVRRIIQGKGLYTINNIV
                     EINNLISIKSLYPVGTYNVSKLHSPVCFTVGDEGEQYKGIGKELINIENLPILSDSVG
                     KFGSPTSDSERAMITEDANEILICIFSFSQESDIEEYFGYAKELLKEYADGKDIETKI
                     IK"
     gene            6805..8214
                     /locus_tag="KR294_001333"
     CDS             6805..8214
                     /locus_tag="KR294_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase/peptidoglycan binding
                     protein"
                     /protein_id="HBH0239415.1"
                     /translation="MIDGKEVKQESGQKNLKFKIAIVVGVLFVAYIGMAIFFRNHFYF
                     GTTINGVKASGKTVEQVNDLLASSTNSYTLNLEERNNKKEQIKAKDIDLKFTPDDKVQ
                     KIKDSQSAIGWIGGIFKSKEYNNMITLSYNKDLLEKRFNALSCFDSKNVVEPKSAYPK
                     YDSTKNAYVIVPEVLGNKVKKDDFYKLVQNSINSGNTSISLDESKVYEAPNNTKDSEK
                     LKQAIKTLDKYVGVVVTYDFSDRKETLDGSEINKWLKVDSEKNYDITFDNDAMVEYTR
                     GLSKKYSTFGDSRPFKTATGKDITISGGIYGWLIDKKKEAEALVDVVKAGKNVTREPI
                     YIQKAVSRNKDDIGNTYVEISLSGQHMWFFKNGEMLVSTDVVTGDLARGFATPSGIYP
                     LNYKARNVSLTGQGYSSPVSYWLPFNGNIGIHDATWRNSFGGSIYKSSGSHGCVNTPF
                     SKAKKIYENIEPGTPIILY"
     gene            8329..8604
                     /locus_tag="KR294_001334"
     CDS             8329..8604
                     /locus_tag="KR294_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif11-like leader peptide family natural product
                     precursor"
                     /protein_id="HBH0239416.1"
                     /translation="MNEKLTKILEEAKNDDEFRKELIKTREQRDVMDSFCKVVTSRGY
                     DMTVGELFSMGEEYTSNLLKSVNGGAAYPIEDWSDWYEDFFIMLSNI"
     gene            9234..9545
                     /locus_tag="KR294_001335"
     CDS             9234..9545
                     /locus_tag="KR294_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239417.1"
                     /translation="MAFEIIKSIVEAEQTADSIKVKAVTDAESIRADAVNKCESIFAD
                     VKKQAKLMEETLIEKAVTDSRAEVDKILANAKSECLKIEKTAEERKSKAIEAVIGKVV
                     R"
     gene            9547..11472
                     /locus_tag="KR294_001336"
     CDS             9547..11472
                     /locus_tag="KR294_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HBH0239418.1"
                     /translation="MAIVNMNKISIVGLEAQKSQILKLLMNRGFVQIDDSAFLTEEEE
                     LKNYLVKDSEESEVIMLEQKMSHVNQAINIVSSLVKQKKSLLAPKREFNKIDSEKEGQ
                     VYAEALELNNLHKEIGTIRSNINLLNNNKSMLEPWVNFDIPIENMETKYTKTILGTVP
                     ISANIDALRVKLEDEIPESVIGIVNSDKLMNYVYLITLKETFDDVLEVLKEFNFSVVS
                     LPNEEGTPLQAIKKYNEMIIRQENVSKDKTEEIKRHADSIHMLENLYDFYTIERDQKK
                     IIERLVKTKTTFCLNGWLPSKRADELIKEITEKFDCCVQTEEGSKEEGFPILLENNKL
                     VTPFESVTNMYSYPSTKDIDPNTILTFFFVIFFGMMLSDAAYGLIIAVVCGFVVYKLK
                     IQKGEGNLIKLIGICGVSTTVWGLIFGGILGDLIPIKALINPLEDVMTLMGMSLLFGI
                     IHIYVGLGIKAYTLIRSGKVIDAIFDIGFWYLCITGVCLLIIPFVAGDIGVFSEVGKY
                     LAIIGAIGLVLTQGRSFKGIPVKLFKGFSSLYGITSYFADILSYTRIMALCLTTGVIA
                     QVINLLGAIAGPILAVVIGVVGHTINLLINALGAYVHTSRLQYVEFFNKFYEGGGVPF
                     VPFKYKTKYTSINKKEM"
     gene            11475..11966
                     /locus_tag="KR294_001337"
     CDS             11475..11966
                     /locus_tag="KR294_001337"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HBH0239419.1"
                     /translation="MEFLNALGNGQFLAISGAAIAALFAGMGSAKGTSIAGQAAAGVV
                     TEDPSKFGQLLVLQLLPGTQGLYGFIIAFLILSKAGIIGGDAIPTSAQGLQLLMAGLP
                     IGLVGLVSGIAQGKAAAAGVGIVAKRPEELGKAITFAAIVETYALLGLLVSFLAYNGI
                     AIG"
     gene            12018..12581
                     /locus_tag="KR294_001338"
     CDS             12018..12581
                     /locus_tag="KR294_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit E"
                     /protein_id="HBH0239420.1"
                     /translation="MGNEQKMIDRIIADAKQEAQEILDKAKSEADLKVNSANEKAEKE
                     MASYTKLAEAEAEKAASKEISGAYMEAKKQILSKKQEILEEVILEAKNKLLNLKDNEY
                     EEIILNMIEKSNCTDDSEIVLSKKDKKTLKDVLSKKGIKVSDETRDITGGFIVKKGDI
                     EYNYSFEAIIAVEHEYIEQIAAEILFN"
     gene            12596..13573
                     /locus_tag="KR294_001339"
     CDS             12596..13573
                     /locus_tag="KR294_001339"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit C"
                     /protein_id="HBH0239421.1"
                     /translation="MAEEKTYPYAVARIRVLEKQLLNRQMFIQMAEAKSPEDSLRIIA
                     EAGYADTSNNNIHNFENILTQELSKTYEILKSLAPEEKFVDVFLYKNDYHNLKVLIKE
                     EISGVDGEKYLIDGGTIPLIKLRESLANRSFSDLPKIMSSAILEAFDVYNKTQNGQMV
                     DIVLDKATFTSMKETAKESQNKFVIDYVMKVCDLTNLKSFIRVKNMKKDFDMFMNVFV
                     SGGSLDKEKFLEAFSSDTPASCFKSTSYSDVCKNGMDSGFTVFEKLCDDYLMEYVRGA
                     KFKPLTLEPLIAYLYAKESEIKTIRIILTSKLNNIDADTIKERLRDAYV"
     gene            13560..13883
                     /locus_tag="KR294_001340"
     CDS             13560..13883
                     /locus_tag="KR294_001340"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HBH0239422.1"
                     /translation="MLMYKVGVVGDKDSIMGFLALGIDIFPAYDSDEIKKSIHKLVED
                     EYAIIYITEQASLLAKESIAKYKDYQLPAIIVIPGIGGSMGLGMNEVRESSKRAIGAD
                     ILFKE"
     gene            14000..15778
                     /locus_tag="KR294_001341"
     CDS             14000..15778
                     /locus_tag="KR294_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HBH0239423.1"
                     /translation="MKTGTIVKVSGPLVVAEGMRDANMFDVVRVSDKHLIGEIIEMHG
                     DKASIQVYEETSGLGPGEEVVSLGMPMSVELGPGLISTIYDGIQRPLEKMYDISGTNI
                     TKGVEVSSLDRTTKWEFKPKKSVGDKVVAGDIIGGVQETAVVECKIMVPYGVKGTIKE
                     IYSGEFTVEDTVCVITDEKGNDIPVTMMQKWPVRKERPYREKKTPDSLLVTGQRVIDT
                     FFPITKGGVAAIPGPFGSGKTVTQHQLAKWADADIVVYIGCGERGNEMTDVLLEFPEL
                     KDPRTGESLMQRTVLIANTSDMPVAAREASIYTGITIAEYFRDMGYSVALMADSTSRW
                     AEALREMSGRLEEMPGEEGYPAYLGSRLAQFYERAGKVNCLGMDEREGTLTAIGAVSP
                     PGGDTSEPVSQATLRIVKVFWGLDASLAYKRHFPAINWLTSYSLYQEKVDVWADKNVN
                     DNFSAQRAQAMKLLQVESELQEIVQLVGVDSLSDGDRLILEVTRSIREDFLHQNSFHE
                     VDTYTSLHKQYRMMGLILKFYKSAQDAIKQNVTINDIIKLSVLEKIGRAKYVEEGDID
                     AAYDSIEDEIDNELADLIKKRGAEEL"
     gene            15775..17148
                     /locus_tag="KR294_001342"
     CDS             15775..17148
                     /locus_tag="KR294_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HBH0239424.1"
                     /translation="MIKEYKSIQEVAGPLMLINGVEGVKFDELGEIELSNGEIRRCKV
                     LEVNGDTALVQLFESSTGINLAESKVRFLGKSLDFGVSPDILGRVFSGMGRPIDGGPE
                     IIPDKRLDINGAPINPAARDYPAEFIQTGVSAIDGLNTLVRGQKLPIFSGSGLPHANL
                     AVQIARQAKVRGTDSKFAVVFAAVGITFEDAEFFISDFKATGAIDRSVVFVNLANDPA
                     VERVSTPRMALTAAEYLAFEQDMHVLVIITDITNYAEALREVSAAKKEVPGRRGYPGY
                     LYTDLATMYERAGKMKGHEGSITMIPILTMPEDDKTHPIPDLTGYITEGQIILSRELY
                     KKDIQPPIDVLPSLSRLKDKGIGKGKTREDHADTMNQLFAAYSRGKDAKELMAILGES
                     ALSEIDLMYAKFADEFEKEYVSQGFRTDRTIEQTLEIGWKLLSMLPKSELKRIRDEYF
                     EKYMPKE"
     gene            17154..17822
                     /locus_tag="KR294_001343"
     CDS             17154..17822
                     /locus_tag="KR294_001343"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HBH0239425.1"
                     /translation="MARLNINPTRMEMTRLKKLLKTATRGHKLLKDKLDELMKQFLEI
                     VRENKRLREEAENALDTAYKNFIIARAVMSQEYLGSALMMPKQSVSVDVSTRNIMSVD
                     VPVFDFKTENNQSDIYPYGLAFTSGELDSAMEAFSDAMQPLLRLAESEKSAQLLAQEI
                     EKTRRRVNALENVMIPNYIETIKYIAMKLEENERASTTRLMKVKDMVLKKALEEKKKN
                     DLVV"
     gene            18099..19148
                     /locus_tag="KR294_001344"
     CDS             18099..19148
                     /locus_tag="KR294_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HBH0239426.1"
                     /translation="MKEFIFTCLCIVVITFMTSCISTTPQTTQGKGNNKLTIYAALEE
                     EQIAYYMEGFREEYPNIDVEIVMDSHGVIASKLLAEKDNPQADIIWGLSAMNMIELKK
                     DGALEAYKPKNYDKVDKKFKDTEDDVSWVGMSVPETAIVVNYKELKKLGIDIPKSYED
                     LIKPEYKGLITMPNPASSGTGYLTVSGLIQMMGEKDAYNYMDKLHKNIATYTHSGSKP
                     AKLAGSGEYPIGITLGYRATQQLSSGEPIEVVFPKEGSGWDLEANALVKKDNIKKEAK
                     LFLDWAISDSAMDRYAHEVAVTSIKTDNPVPKGYSKQPFEQLIKEVDLNSAAKNRSTV
                     LKTWESKYGSKSESK"
     gene            19244..20233
                     /locus_tag="KR294_001345"
     CDS             19244..20233
                     /locus_tag="KR294_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH0239427.1"
                     /translation="MSYLKINNVFKSYDQKKVLNNISLDIEEGEFLCLLGPSGCGKTT
                     LLRIIAGLEDVNSGTIILQDKDITNLEPSKRGFGIVFQSYALFPNMTAYNNIAFPLKE
                     RKVSKEKIDNKVKEVLETVGLTNEAHKYPKALSGGQQQRIAIARALALEPKFLLLDEP
                     MSALDAKVRHKLRMDIKRLQKELNITTIMVTHDQEEAITMADKIAILNGGDIMQIGTP
                     EEIYQNPQNLFTAQFIGDTNCFDNGDSILTVRPEYVQIEKSTKENYQGIISNIEFRGN
                     LLRVEIKDKLNENFIISDVSIKEWVNLNLVEGDLVKISIDEKYYLKYPKVKGA"
     gene            20238..21956
                     /locus_tag="KR294_001346"
     CDS             20238..21956
                     /locus_tag="KR294_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     permease subunit"
                     /protein_id="HBH0239428.1"
                     /translation="MNNNAISSKSISLKSKMNLDIKKCMLTVLVMSLVIFLLAPIIYL
                     FVQAFLDKDGVFVGLQNFQEYLASESLLNSLKNTVFVSVISTVISLTLALVYAYALTR
                     TKIKFKGFFKSLAMFPMFAPTMMHAIGLVYLFGNQGLVTNLLGVHVPIYGAVGIILAQ
                     IIYVFPQSFQILYISLSSTDYRLYEASNTMGISKIREFISITIPSIKYSLISSAFVSF
                     TLCFTDFGAPKVIGGEFNVLSIDVYKQIIGQQNMPMGATVSILLLIPAIISFIVTKKI
                     EKNQNSYITSKSIPYKVKTNKLRDSILGGVVGIIAFGIIAVMLTVILSSLISVWPYDL
                     RLTLEHFSMKNSIDGIKPFINSIKMSLFTAILGTSFVFLFAYLNEKTEKAPYLKSFGY
                     FLSTLPMALPGLVLGIAYVLFFNKLEFNFMDTIYIKNLFNGLYGTLLIMVICNIVHFF
                     SVAFITATTAIKKVDKELDMVAKSMGINSASILKNVTIPLCLPAVLENFMYFFLNSMV
                     TISALVFIYTASSKVAAISIVQLDDKGSTAQAAALAVLILVTNILVKVIYEFIKNRLE
                     KRTNFN"
     gene            complement(22038..23192)
                     /locus_tag="KR294_001347"
     CDS             complement(22038..23192)
                     /locus_tag="KR294_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBH0239429.1"
                     /translation="MKINKKFNRVDMQVSILTAIIVIISSSCVYFFNYTLTYKSMIYS
                     LSERSKHIYEYVERNIDKNTFTEINSKEDQSKKSYKSSKILLESVKNTTGVMYLYTAK
                     KTKDGSLVYVVDGLNSSRSDFRNAGDLIEKEIWGDLNKALDNHILLPKKIKSTSWGYI
                     FISYFPIHNDVGKVVGVIGIEFEAKHQYNTFKFISIVTPIIALLTCLISALIAVILFK
                     RISNPTYTDFANTDYLTGLKNRNAFEIDMNNLNNSNLKNLISIISIDLDGLKKINDKF
                     GHQTGDLYIKQASKIIQYVINKKYIVYRIGGDEYIIILKNLSHKEINNIINNINLKIV
                     EENSTNELKLSMSIGYAIFDEKVDVSLFDTYRRADSQMYDNKRKINKQYQ"
     gene            23691..25052
                     /locus_tag="KR294_001348"
     CDS             23691..25052
                     /locus_tag="KR294_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBH0239430.1"
                     /translation="MKDRLNLTEGRITEKLLKLSLPIMGTSFIQMGYNMIDMIWVGKA
                     GSKAVAAVGTAGFFPWLAMAFIMISKVGGEIKVAQSIGANNISTTKSYMKSAIEINII
                     LAIIYTISLIVLNKQLIGFFRLGDLEVITMSRQYLIIVALGMVFYFINPVFTAIFNGL
                     GNSKTPFRINTVGLITNIILDPILIFGWGFAPKLGVAGAAIATVFAQIVVTTCFIYII
                     VKSKEEYFKLRLFKEIETKYYKVLYKLGLPIAIQSGMFTVFSMLLGVIVASWGPVAVA
                     VQKVGSQIEAISWMTAEGLSVALGSFVGQNYGAKKYSRINKGCKIAITVSSVLGIITT
                     LVLVFAGESIFSIFIDESEAIEKGAVYLKILGYSQFFMCLEIITTGAFKGLGRTYIPS
                     IIITILTGARVPLAYFISRPEMLGLNGVWWSITLSSILKGILMISLFISLLKLGKLYK
                     ISE"
     gene            25143..25847
                     /locus_tag="KR294_001349"
     CDS             25143..25847
                     /locus_tag="KR294_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH0239431.1"
                     /translation="MKEPIYKVIENHVRELINSDSLKEGDLIPSEKQLSEEFNVTRMT
                     VRSALNNLVKEGYITRQRGVGSIVIANNIYDNISSVSGFTKEMESKGYKVSNILVSLE
                     IVQADENLSSKLNISLEENVWEIKRVRLANDARVSYMITYMPVKLFPNLNKTHCENSL
                     YNFVEEVCEYKIAMSEREVQAVISNEECMDNLKLEEPEPLLYISQICKLQNSEIFEYS
                     HTYHYGYTLTLNAVVE"
     gene            26047..26358
                     /locus_tag="KR294_001350"
     CDS             26047..26358
                     /locus_tag="KR294_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH0239432.1"
                     /translation="MIKIMLACSAGMSTSLLVTKMEDAAKENGIEAKIWAISEVNLKN
                     EIENCDVLLLGPQVRYVLGKATEMAKPYNIPVEVINMMDYGRCNGKAVLDRAVELNSS
                     K"
     gene            26380..27693
                     /locus_tag="KR294_001351"
     CDS             26380..27693
                     /locus_tag="KR294_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH0239433.1"
                     /translation="MEKFMSFMDKYIVPVAAKIGAQRHLVAVRDAFIVMIPITMVGAL
                     GTLINNLPLEAYKNLMASIFGENWTTFGGDLWWGAIGTMAVFLVIGVAYFLAKSYESD
                     GLQSGLIALSIFFIMAPQIGKIVPEGGTTVVEGWGMIQQTYLGTAALFSSILIGLLST
                     EIFVRLSKVKKLTIKMPDGVPPAVSRSFAKLIPGMLTIMIFTVIGIFIKMLSNGSFLT
                     DILNTYLGAPLSNVADSLGSTMLIAFIIHILWTVGLHGANIALPFTETILMKLGGENA
                     ALAQAGATEGYHVLAGAFFDAFVYLGGSGMVLGLIVALLIAGRRRKEMIVLGGPPAIF
                     NIGEPLIFGLPIVLNPIFMIPFVLAPVICSAVSYLAIDFGLVAPVILPKIPWVTPPIL
                     GGAMATGDWTGGALALFNLILSILIYIPFVIASEKMEANKLKINN"
     gene            27790..29100
                     /locus_tag="KR294_001352"
     CDS             27790..29100
                     /locus_tag="KR294_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBH0239434.1"
                     /translation="MKKGLKIVTIGGGSSYTPELVEGFINRYEELPVKELWLVDIEAG
                     KEKLEIVGNLAKRMVKKAGVDMKINLTLDRREALRDADFVTTQLRVGLLDARIKDETI
                     PLSHGVMGQETNGAGGLFKALRTIPVIFDIIKDVEELCPNAWMVNFTNPTGIITEAVF
                     KYTNFRRYIGLCNVPIHLKNDVAKLFNVESDRISMDFAGLNHMVYGLNVSLDGEDVTK
                     EAIDKFVKADISMQNIKAIDFNAEFVKSLGAIPCPYHRYYYKTKEMLEDELREFKEGK
                     ARGQVVKELEEQLFELYKDEKLDVKPPQLEKRGGAYYSDAACNLISSIYNDKKDIQVV
                     NTLNKGSIRDFKDEQAVEVSSVITKNGPKPISIGYLPDSVHGLVSQIKSFEVLAAKAA
                     VYGDYESALLALCINPLIPSDDLAKTILDEMLEAHKDYLPRFNR"
     gene            29126..29857
                     /gene="chbG"
                     /locus_tag="KR294_001353"
     CDS             29126..29857
                     /gene="chbG"
                     /locus_tag="KR294_001353"
                     /EC_number="3.5.1.105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chitin disaccharide deacetylase"
                     /protein_id="HBH0239435.1"
                     /translation="MTKIIINADDFGYCEAVNYGIISAHNNGIVRSTSMMANMPGVEH
                     GVGLLKENKTLNCGVHMTLSCGRPLLSNLKTIVDKDGFFIRRITDEIIEKMDCDEIYR
                     ELCAQIDRVKGLGIDISHLDSHHHIHTLVSLKPVIEKIVTKYNLPIRGGFEYNLEYSK
                     VVPLIDSFYKENVSEEYFIKNIDEIMKYDVVDIMSHPAFLDDYILNSTSYAIDRTKEH
                     KILTSKKVKEFLEKNGLVISSYRDI"
     gene            29870..30187
                     /locus_tag="KR294_001354"
     CDS             29870..30187
                     /locus_tag="KR294_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBH0239436.1"
                     /translation="MDEKMIEISFGIIGFAGDAKGLAFEAIKEAKSGNIDKARECIEK
                     SKESIHKAHKFQTELIQNEANGNKTEISVILIHAQDHLMTAMNFQQLAEEFIDVYERL
                     ESK"
     gene            complement(30299..30763)
                     /locus_tag="KR294_001355"
     CDS             complement(30299..30763)
                     /locus_tag="KR294_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016208838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239437.1"
                     /translation="MVHLVYCDNAGKKGEKVLDKILDGTKTMVIRGAAGRKIPHSRVF
                     EDELLYFMEKGTAKISAKATVKKVENYVKLTEDEISKILNENQPKLNLSEKQKVRWHK
                     KCLCLVEFENVEEITPLDFDHQGNMDDWLIVEKIEDVVVGTSIPYNYEKSKF"
     gene            31033..31971
                     /locus_tag="KR294_001356"
     CDS             31033..31971
                     /locus_tag="KR294_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBH0239438.1"
                     /translation="MKKIKSLAIFISIITTLVLVTACSDKNTEDKDKSETRVVQSVKG
                     EVKIPSNPKKIVDISGSSEELLLAGYKPVATANVDSYETDKLPSYIREELKGVKIVGH
                     SMMDTMDMEAILEVNPDLIIMSQRQEKIYDQLKEIAPVVMMKDYANDWRSKLTDVSKL
                     FDKEEEDKSWLQKYDEKATKLGKEVIEKNGEKTYLPVLASSGQFMVFSDGGIGTLIND
                     DMKLARPKNMPKQDGITLPMVSMEGLTDIDADHIVVIATEADKKDLENSAIWAQIRAV
                     KDGNVTILDAAPFFSQSYNPIGKELLLESVKNELTK"
     gene            32099..33112
                     /locus_tag="KR294_001357"
     CDS             32099..33112
                     /locus_tag="KR294_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HBH0239439.1"
                     /translation="MTKLSKKNITYLLILVSIVVLVFGIVLSITIGAKDMNLSTVIDS
                     LIKMEDGINMRIVKDVRLPRAIAAALVGGFLAVSGAIMQGITRNPIAEPSVIGITQGA
                     TFAISISLVLQKKLPQLIHGSFSVMMFAFIGASISGLFIYFISSKSRGRVNNVKLALA
                     GVALGTLLISLASAISMYFNLSQQLSFWISGGLVGVKWEGIKLLFVAGGIGFILAIIM
                     APRITILSLGEEVAIGLGQKTKFVRFICIVLVILMTGASVSVSGNIIFIGLIVPQIAK
                     GIVGSDYKYIIPSSLVLGAVLLVYTDILSRMINPPYETPVGSITALIGVPIFIYLVRK
                     GEK"
     gene            33118..34140
                     /locus_tag="KR294_001358"
     CDS             33118..34140
                     /locus_tag="KR294_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HBH0239440.1"
                     /translation="MKNIIKINSKTLLVISILMVLIFITFLLSLNMGSFSIEPMDVIK
                     TFLGQGQRNHEIAIFKLRLPRIVIALLVGSALSTAGVILQGVTKNDLADSGILGINSG
                     AALFVVVYIYLMNGNVYEGMSNLTVFTMPIVALIGALFGAFLIYSLAWKGGINSSRLL
                     LIGIGVNIAFTSILTIFQLKFTTQEFNRVMAWTSGSIWGTSWKYVIAVLPFIVIFMGI
                     TIYKSKYIDVLNLGDEVSISLGVDVEKQRRRLIIYAVILSGVSTAVAGSISFLGLIAP
                     HIGRKIIGPKHKRLIPVSALIGTLLLLIADTISRNLLAPIEIPVGIVVSIIGVPYFIY
                     LMLVND"
     gene            34155..34937
                     /locus_tag="KR294_001359"
     CDS             34155..34937
                     /locus_tag="KR294_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004460318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0239441.1"
                     /translation="MNCINTKNLNVSYGNTDIIKNLNLNIPKGKITTIIGANGCGKST
                     ILKTIGRIISPNSGKIYINGEDIYKKKSKEIAKDMAVLPQSPQAPSGLTVSELISYGR
                     FPHKSGFGNSSKEDREIVNWSLEVTGIAEFKDRNMEDLSGGQRQRAWIAMALAQETDI
                     LLLDEPTTYLDLAHQLEILKLLDELNKKQGRTIVMVIHELNNAARFADHMIGIKKGKI
                     VCEGDAYDVMTKDNLKELFNIDAEIATDPRTNKPICITYDMV"
     gene            34949..36289
                     /locus_tag="KR294_001360"
     CDS             34949..36289
                     /locus_tag="KR294_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBH0239442.1"
                     /translation="MENQEALRHEKIWILLFRYSIPAIIAMMVTSLYNVVDRAFIGSM
                     EGIGSIAIAGLGVTMPVFTLIIAFGMLVSVGASTRLSIKLGERNREEAEKILGNALTL
                     SIIISLIITILGLVFLEEILFILGASKDSIFYAKDYMSVILVGSIFNLVAFSLNNAIR
                     AEGNPKLAARTMIVGCVLNLILDPIFIFVFNLGIKGAAIATVLCQIVVFFWVIHYFIR
                     GKSNLKLKKCNLKLNKDIVKKVFAIGMTPFAMEVAISITHMFTNNSLKVYGGDLAIGA
                     MTALTSILLMFMMPVFGLNQGMQTIISYNYGAKQYERAKKTLILSIIVSVVILSFGFL
                     VVQVFPEVFVGIFNKDSDLMDIAVRGISLNLITLPIMGISIVGPVYFQCISKVKHSMF
                     LTLLRQFILFIPLIIVLPIQFNLDGVWLAQPVADFIAMIIVLLFLKREFKTSRV"
     gene            complement(36384..38663)
                     /locus_tag="KR294_001361"
     CDS             complement(36384..38663)
                     /locus_tag="KR294_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBH0239443.1"
                     /translation="MNFENTKNKKIIATLLLTLLLIVSLTCVTFIMNLNKVTHNETER
                     YLVEVSQGISTTINVKCKSIFRTLYSMGDTYFEINDSEKEVNRYLSKKLKLFEFDWLG
                     IIDSNGNFVSALKDTGNVKGQDFYRKALQGKETITPVKSQSGTYGILYSVPLYNGDKI
                     VGAVAAWNTIDTMRNLLSVESFHGEGFSQIIDQDGNFIVSSANKNAPKNVVNFFDMIK
                     HQGKQVDKNKLEEMKINLKKNKTGSMYYTLNDGISKAMHYLPLQEENLYLLSIVPTKT
                     ASAQFDLLLKKAIFINILIVILFLLLIILIMFINQKNRAQLIKIAYVDSVTKGYSKAR
                     FDIEAKKIIQSSSSESYSLVSINIQKFKLINDSFGSEAGDKTLKYIHDVISNYLEPGE
                     LLCRVSNDQFNVLIKTIPQKEILKYIENITNDINSFNKNEECKYFIALSIGVYKIDDP
                     NLPLVSIQDRANVARKNNKGNIGNHPLYTCVFYSDLERLKMIKEKEMENRMEEALNNN
                     EFIVYLQPKISLKDNTIVGAEALVRWQDPNKGLIPPDEFIPFFEKNGFITKLDHYVFE
                     KVCSMIRKWIDNGETPIPVSVNFSRANLNNIDFLEKYRMLRNKYNIPAKLLEIELTET
                     LVFENLQKLINIIDQIHEEGFQCSLDDFGSGYSSLNMLKEIKVDTLKLDRAFFSSPNA
                     DNIAENHVIESIVNLAKKLNMNSISEGVETILQMDYLKKINCDMIQGYVFSKPLPQEI
                     FEKMTFGKKLEETSMDSSV"
     gene            complement(39000..40163)
                     /locus_tag="KR294_001362"
     CDS             complement(39000..40163)
                     /locus_tag="KR294_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HBH0239444.1"
                     /translation="MKLMGYLRENGQFGIRNHVLIIPTSVCSSETATRIASLVPGAIA
                     IPHQHGCCQIGSDIELTAKTLIGFGKNPNVAAVLVVGLGCDGIQAKELASEIATTGKK
                     VDYVVIQECGGTLKTVSKGAEIVSKMAREVSKEVRVEFGMSEITLALECGGSDPTSGI
                     ASNPSIGVASNLLVDEGGSSILSETTEVIGAEHLLATRFEDEEMKDKFLKFVSDVEKR
                     AIAMGEDLRSGQPTPGNKTGGLSTIEEKSLGCMYKAGNKPFKGALEYADIVPPDKKGL
                     YFMDTPGQDIDSITGMVAGGAQIVIFSTGRGTPTGSPISPVIKITGNSDTYNKMPDNI
                     DINAGRIITDGAKIADIGQEIFNEIIEVCNGKHTKAESLGHREFGIYRISSTF"
     gene            complement(40176..40451)
                     /locus_tag="KR294_001363"
     CDS             complement(40176..40451)
                     /locus_tag="KR294_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HBH0239445.1"
                     /translation="MNAIIHANEKDNLVTCVRPLVKGEKVSIDGKSYIVNDNIPVFHK
                     MATEDVKKGDVVYKYGEIIGIATVDIKTGDYVHVHNIESTRGRGDKK"
     gene            complement(40472..41446)
                     /locus_tag="KR294_001364"
     CDS             complement(40472..41446)
                     /locus_tag="KR294_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-3-deoxygluconate permease"
                     /protein_id="HBH0239446.1"
                     /translation="MHILKSVKKIPGGLMVCPLLLGALFNTVCPQALEIGGFTTSLFK
                     TGAMSILALFCLCNGAQINIRQAGKPLTKGIVLTATKFIIGAVLGIIVSKFIGPKGII
                     GITPLAIVATMTNSNGGLFAALAGEYGDSTDVGAISILSLNDGPFFTMLAFGVTGLAN
                     VPIIALFAALIPILLGFILGNLDEDIREFLAPGTTLLIPFFAFPLGAALNFNQIITAG
                     LPGVVLGLGVTIITGMGGYFVMKLIRAEHPAVGAATGTTAGNAAGTPEALAAIDPTLA
                     TIAAVSTVQVAAAIIVTAICCPMLVSYLDKREKKKKSIFKTNKNIEVN"
BASE COUNT        15546 a         5101 c         7341 g        13777 t
ORIGIN      
        1 atttacttta acttgttaat taagttttaa ttttcatttt caaggatttt tatttttaaa
       61 cttgatagag tatcatatta aaaattcttt ttataaagtt ttatttgcaa aaaatacaaa
      121 aatataaacg ttaaaaaaat aacgttatcc ttaagttttt agatgatttc attagtgatt
      181 tgcgtaaaaa ataaagtgat atctagttaa attaagtatt tgtaaagcta gatattatta
      241 gtagaaatga tgttatatta gataaaaaat aaaatgttaa aaaaataact tgaaaatagg
      301 aaaagtaaat gctataatgt taataaatta acataataaa taaaaaacta tctcaggagg
      361 ttgttaaaat ggctcataaa gaacaagtaa taatagaaaa taaaaaagaa aatgaagtta
      421 tgtcagttgg tttagatact gtaaataacg ttgaaagctt agttaaaaaa ctagcaaaaa
      481 tcagagaagc tcaaaaaata tttgctacat atagtcaaga gcaggtagat aaaatttttt
      541 tagcagcatc tttggcagct aataagcaaa gagttcctct agctataatg gcacaaaaag
      601 aaactggtat gggaattgct gaagataagg ttataaagaa tcattatgcc tcagagtata
      661 tatataatgc atataaagaa actaaaactt gtggtgttat agagaaagac gaagcatttg
      721 gtatgactaa aattgctgaa ccaataggtg ttattgcagc agttgtacct acaactaatc
      781 caacttctac tgctatcttt aaagcacttt tagctttaaa aactagaaat ggaataattt
      841 tctctccaca tccaagagca aaaaattcta ctatagaggc tgcaaaagtt gttcttgagg
      901 ctgctgtttt agctggagct cctgaaggta taataggatg gatagatgag ccatctttag
      961 aattaactac aactgttatg aaagaagtgg atttgaccct tgctacagga ggtcctggaa
     1021 tggttaaatc agcatattca tctggaaaac cagctattgg agttggtgca ggtaatactc
     1081 cagcaataat tgatgatagt gcagatataa aaactgctgt aaactcaatt cttgtatcta
     1141 agacttttga caatggtatg atatgtgctt ctgaacaatc ggttatagta ttagaaaata
     1201 tatacaatga agtcaaaaaa gaatttaaag agcgtggtgc ttatttatta gataaagatg
     1261 aaacagaaaa aataagaaat ataattttag taaatggagg attaaattct aaaatagttg
     1321 ggcaaacagc ttgtactata gcaaaacttg caggctttga agtcccagta gatactaagg
     1381 ttttaatagg tgaagtagaa tcagttgaaa tagaagaagc ttttgctcat gagaaacttt
     1441 caccagtact tgcaatgtac aaggcaagtg attttgatga tgcagttaga aaagcagaaa
     1501 aattagtaga agatggtgga tttgggcata catcttcatt atatattgat gatgtaaatc
     1561 aaagagaaaa acttgataag tttacttcag ccatgaaaac ttgtagaatt ttaattaata
     1621 ctccttcttc tcaaggtggt ataggggact tatataattt taaactagct ccttctctta
     1681 ctttaggatg tgggtcttgg ggtggaaatt cagtatctga aaatgtagga gttaagcatt
     1741 tacttaatat taaaacagta gctgagagga gagaaaatat gctttggttt agagcaccag
     1801 aaaaagttta tttcaaaaaa ggttgtttag gagtagcatt aaaagaactt aaagatgtaa
     1861 tgaataagaa gagagctttt attgtaacag atacattcct ttacaataat ggatatacta
     1921 aagcagttac tgatttatta gatgaaatga atattaagta cactacattc tttgaagtag
     1981 aaccagaccc aactttggaa tgtgctaaga taggcgctaa agctatgaga gaatttaatc
     2041 cagatgtaat aatatctata ggtggaggaa gtgcaatgga tgcaggaaag ataatgtgga
     2101 cattgtatga gcatccagat gtagatttcc aagacctagc tatgagattt atggatataa
     2161 gaaaaagggt atatacattc cctaaaatgg gtgaaaaagc taattttgta gctataccaa
     2221 catcagcagg tactggttca gaagtaacac catttgctgt tataactgac caagatacag
     2281 gagtaaaata tccattagca gattatgaac tgatgccaaa tatggctata gttgattctg
     2341 atatgatgat gaatatgcca aaaagcttaa catctgcttc tggtatagat gctttaactc
     2401 atgcattaga agcatatgta tctatgcttg caaccgatta tacaaatgga ttagctttac
     2461 aagctattaa gagtatattt gaatatcttc cacgtgcata tgataatggt gcaaaagacc
     2521 cagaagctag agaaaaaatg gcaaatgctt ctacaatggc aggtatggct tttgcaaatg
     2581 catttttggg tgtttgtcac tctatggctc ataaattagg tgctttccac catgtaccac
     2641 atggtgttgc aaatgctctt ttgataacag aagttatgaa atttaattct tcagatgcac
     2701 caaagaaaat gggagcattc tctcaatata aatatccaga agcattaaag agatatgctg
     2761 aaatagcttc atttttagga ttaaaaggaa attctgatga agagaaattc caaagtttat
     2821 tggtagctat tgaagattta aaacttaaag ttggtattcc taaatctata aaagagtttg
     2881 gcgttgaaga atctaagttt atggattcaa tagatgaaat ggtaattcaa gcatttgatg
     2941 accaatgtac aggagcaaat ccaagatatc cacttatgaa tgaaataaaa gatatgtatt
     3001 taaattcata ttatggaaga taagtttgct ataaaataga taaaataaaa actcttatac
     3061 ataaaacaaa gttttattgt ataagagttt ttttgtttga gaaaatggat agtttttatt
     3121 ctttaattta aaattcaatt aaatagtgtt attataataa taaaagaatg tttttatggt
     3181 tattatgttg attttatgtg taacatttaa gaatagttat atacaatata aatgatgaat
     3241 tggtataaaa aggatatatt atctatatga agtattgact aattagggga ggagtcgaat
     3301 gacagggaga aataaaagtt ttacattaat tacaattctt tttttaacat cattattttt
     3361 gacaatgggg tatatctata tagaagatac aaaacatctt cttatgtcag aggcaaaaat
     3421 acatataaaa gaagttgcag tacaaggctc tcaactagca caaagacaaa ttgaaaaaga
     3481 tttagatgtt ttaaatattt tttctaacta ttatgcttca aatccagata tacctaatga
     3541 ggaaaaaatg aaaaatcttt tagatgaaat ggaaaatcaa aaattttaca ctatggcaat
     3601 agttgatata aatggtaatg ctgaaaatac caaaggtgat aagttttcag tgaaagatag
     3661 agaatttttc aaaaactcaa ttaaaggtaa gaagtatgtt tcaagtccat atgttgatga
     3721 agtaaataag tctataaaga agattgctat ttcagtacca ttattaaata atgataaagt
     3781 agttggagtt ttatattgta cttacaatat caatactctg atgaaactta ttaatatatc
     3841 tttttatgaa aataatagta tatcttatgt tgtaaaaaat gatggtacaa ttatccttca
     3901 tccacaaggg gatagcctat caaaaaatat ttataaattg ttagaacagg ataatgatat
     3961 tcaagaagta aatagattaa aaaaagaatt gcaagaaaat aaaacaggtg caactgtatt
     4021 aaatatgttg gaagaaagaa gatatttagg gtatgccact atggataatg ggaatagtga
     4081 aaataattat ataaaagact ggaatttaat tttttcaatt ccagaaactg ttgtatttag
     4141 taattcaaaa caaataatca acagagctgt atatgcagtg ttatctattg tattaatatt
     4201 tgttgcaatt attttttata taatttatat aaaaaaatct aatgaaaaag aaatattaag
     4261 tttggcttat gaagataaag ttacatatat aggaaatcaa aataaatttt atagagaatg
     4321 tagtaagtat cttttagata aaccatcttt aaattatatt atagtatatt ttgatattaa
     4381 taactttaag atgattaatg atacttttgg atatgaattt ggtgacaatt tattaattac
     4441 aatagcaaaa gctttaaaag aagaattaac agaaggtgag gtatatgcac gactttcaag
     4501 tgattatttt gcaattttct gtgattataa aaatggaaga aataaaatta taagaaaact
     4561 tgataatata cgaagtaata ttgaaagtaa tttgagtata gtctttgaaa tttctctgtg
     4621 tgtgggtatt tattttgttg aagaaggtga agtagatatt caaaaggctg taaataaagc
     4681 aaatatggct aggtctgttg ctaaaggtaa aaatataaat tatgctattt ataatgaaga
     4741 tgttaggaat aagcttagtg aggaatcaat gattttagac gatataaaaa tagcattggt
     4801 aaaaaatcaa tttgaagtgt attatcaacc taagttttca cttgtaactg gagaaatgat
     4861 agggagtgaa gcactaataa gatggaatca tccagaacat ggttttataa gtcccgcagt
     4921 atttattcca atagcagaga aaagtaagtt gattttaaaa attgggagat ttgtatttga
     4981 aagggtttgc aatgatttat atgaatggaa aaagcaaggt aaaaagatag ttccagtttc
     5041 agtaaattta tctagggtcg agttgtatca accagatatt gtaaaattta tcaataaaac
     5101 aataaaaatg tataatttaa gttcagattt cattgaaata gagataacag aaactgtggc
     5161 tattaatgag ttaaatattt taaagaatgt tttaaatgag ttgaggacgt atggattttc
     5221 tatttctatg gatgactttg gtacaggata ttcttctatt agttgtttaa gagatatgcc
     5281 aattgatata ttgaagctag ataagtcttt tcttggtggc attgaacatg atgagagaag
     5341 tcgcaatata gcaaaatcaa tagtgtctct agcaaaatca ctagatttag ttgtaattat
     5401 agaaggtgtt gagagtaaag aacaagctga gttaatgaaa caatttggat gtgatttagt
     5461 tcaaggattt tattttgcac gaccaatgcc agctaagaat tttttagatt tactttaaaa
     5521 caaaatttga tttttatata aagcactatt atgaatgctt gattttaata aatcattgct
     5581 aaataattag tgttttttta ttttatcaat gtattgtcta atataaagca aaaaataatt
     5641 gtattttata aaaattatat taaaaataaa tttattttgc taataaacat gttattaaca
     5701 aaagaatagt actataatgt atagatgata aaaactttaa taaaaattta gtgtatagga
     5761 gttgtttaag tatgatagat ataagtattg atgacaaact taaggaaaga tggcctaatg
     5821 ctaagctggg ttgcattcaa gcaaaagtag cagtaaataa aagctcagaa aaattaatta
     5881 atgaaataaa tgagttttgt gatactataa atcaaagtct aaaagttgaa gacattacga
     5941 aactagataa aattaaagat gcaagaaatg cttataaaga gcttggaaaa aatccaagta
     6001 gatatagaac atcttcagaa gcattggtta gaagaattat tcaagggaag ggtctttata
     6061 caataaataa tatagtagaa ataaacaatt taatatcaat aaaatcatta tatccagtag
     6121 gtacatataa tgtaagcaaa ttacattcac cagtatgttt tactgtagga gatgaaggag
     6181 aacagtataa gggtattggg aaagaattaa taaatataga aaatcttcct atattgtctg
     6241 attcagtggg taaatttggg agtccaacta gtgattctga aagagcaatg ataacagaag
     6301 atgcaaatga aatattaatt tgtatatttt cttttagtca agaatctgat attgaagaat
     6361 attttggata tgctaaggaa ttacttaaag aatatgcaga tggaaaagat atagaaacta
     6421 aaataattaa atagaatcta tataacaacg ttatgttaag ctaaaattca atataaaaat
     6481 aagttaagat aaagaaacta acacaaaatt agtttctttt ttaaaatagt agtttagtgt
     6541 tacaaaaata gatagatagt cccacgatta ttaaaagtat ggtaatatat taatatagca
     6601 gagattgtgt ttaagggatt ttgaaagggg ggatttataa taatcatttt atctaaaaga
     6661 taaaatggtt ttatagaaat aactatatat ttaaaaatat aaataatgat acagtaattt
     6721 gggtatataa aataaggcat acatggtttt gtttaaaaac caataaggta cataggtaat
     6781 tacaatgtaa ggaaggattt aattatgatt gatggaaaag aggtaaaaca agaaagtgga
     6841 caaaaaaatc taaaatttaa gatagctata gtagtaggtg ttttgtttgt agcttatata
     6901 ggaatggcaa tcttttttag aaatcatttt tactttggaa cgactattaa tggcgtaaag
     6961 gcttcaggaa aaacagttga gcaagtaaat gatttgttag catctagtac taattcctat
     7021 actttaaact tagaggaaag aaacaataag aaagaacaaa taaaagcaaa agatattgat
     7081 ttaaaattta caccagatga taaagttcaa aagataaaag atagtcagag cgctattgga
     7141 tggattggtg gaatatttaa atctaaagag tataataata tgataactct ttcatataat
     7201 aaagatttac tagaaaaaag gtttaatgct ttatcttgtt ttgatagtaa aaatgttgta
     7261 gaacctaaga gtgcttatcc taagtatgat agcactaaaa acgcttatgt tatagtacca
     7321 gaggtacttg gaaacaaagt gaaaaaagat gatttttata agttagtaca aaactcaatt
     7381 aattctggga atacttctat ttctctggat gaaagtaaag tttatgaagc accaaacaac
     7441 acaaaggatt cagaaaagtt gaaacaagct attaagacat tagataagta tgttggtgta
     7501 gtcgttacat atgattttag tgaccgtaag gaaactttag atggttctga aattaataaa
     7561 tggttaaaag tagactcaga aaagaattat gacataactt ttgataatga tgctatggta
     7621 gaatatacaa gaggtttaag taaaaaatac agtacttttg gtgactcaag accatttaaa
     7681 actgccacag gtaaagatat tacaatttca ggtggaattt atggttggtt gatagataaa
     7741 aagaaagaag ctgaagcatt agttgatgtt gtaaaagctg gtaaaaatgt tacaagagaa
     7801 cctatttaca tacaaaaagc tgtatctcgt aataaagatg atattggaaa tacatatgta
     7861 gagattagtc tttctggcca acatatgtgg ttctttaaaa atggagaaat gcttgtatca
     7921 acagacgttg taacaggtga tttagctaga ggatttgcta caccatcagg tatatatcct
     7981 cttaattata aggctagaaa tgtttcatta actggtcaag gttacagttc acctgtaagt
     8041 tattggcttc catttaatgg gaacataggc attcatgatg ctacttggag aaattctttt
     8101 ggtggaagta tatataagtc ttcaggttca catggatgtg taaatacacc tttttctaag
     8161 gcaaagaaaa tatatgaaaa tatagaacca ggtacaccaa ttattttata ctagtaaatg
     8221 tgttgctaac agttaagcga agtcatccta gtttatttag gatggcttcc tttttatata
     8281 aagcttattg aagtttacag aaagactact taaaaggaga aatacataat gaatgaaaaa
     8341 ttaactaaaa ttttagaaga agctaagaat gatgatgaat ttagaaagga acttataaaa
     8401 acaagagaac aacgtgatgt tatggattca ttttgtaagg ttgttacatc tagaggttat
     8461 gatatgacag taggggaact tttttctatg ggagaagaat atacatccaa tctactgaaa
     8521 agtgtaaatg gaggagcagc atatcctatt gaagattgga gtgattggta cgaggatttt
     8581 tttataatgt tgtcgaatat atagagtaac taatgatatt atctacttaa gattaataca
     8641 ttgccttaaa ataaaactat tagaactagg tgtaagtttt atcaatcttt aaaaatattg
     8701 atttatttct aactagatat aaaaaaatta gattaaaaat aaggtgacaa aaatcgatat
     8761 agcttgatga tttataaaag ttagataaaa tagtgcgaga tatttctaaa aattcaaaaa
     8821 aaacaataaa cttcaatggt tagaggttga aaaagaatat aaaaaacttt tatatgtaat
     8881 aaattaaatt aaaattataa aaaaaataaa ataaaaattt aaaatgtcga cataacgtta
     8941 attttaaaac aaaataacgc tattgacaaa ctatatcgct ttaaattata attattgaaa
     9001 ataatggtat ttaaaaacca tactcatgtc atagtctaaa agtaagtcaa aaaaggatgt
     9061 aaatctaggc aagtactatt ctaaaatatg ttttattaag aaataaacgt tgaaaaatat
     9121 taattattat ataaaaatgc tgtttatact ttaacaatga ggtagtaatc taattagaat
     9181 aaaaaaatct aattggttat atacatagta aaaaggtaag agaggtgatt tggatggctt
     9241 ttgaaataat aaaaagcatt gttgaggcag agcagacagc agacagtatc aaagtaaaag
     9301 ctgttactga tgcagagtct atcagagctg atgctgtaaa caaatgtgaa agcatatttg
     9361 ctgatgtaaa aaaacaagca aagcttatgg aagaaactct tattgagaag gcagtcaccg
     9421 acagtagagc agaggttgat aaaatcttag ctaatgctaa aagtgaatgt ctgaaaattg
     9481 aaaaaactgc tgaagaaaga aaaagtaagg ctattgaagc ggttattgga aaggtagtga
     9541 gataatatgg caatagttaa tatgaacaaa atatctattg ttggcttaga agctcaaaaa
     9601 agccagattt taaagctact tatgaaccgt gggtttgttc agattgatga tagtgccttt
     9661 cttactgagg aggaggaatt aaaaaattat cttgtaaaag atagtgaaga atctgaagtt
     9721 ataatgctag agcagaaaat gtctcatgta aaccaagcaa ttaatattgt ttcttcacta
     9781 gtgaaacaaa aaaaatccct acttgcacca aaaagagagt ttaacaaaat tgatagtgaa
     9841 aaagaagggc aagtttatgc tgaagctctg gagttaaaca atttgcacaa ggagataggt
     9901 acaataaggt ctaacataaa cttacttaac aacaataaaa gtatgttaga accatgggtg
     9961 aactttgata ttcctattga aaatatggaa actaagtata caaaaactat acttggaact
    10021 gtgcccataa gcgcaaacat tgatgcttta agagtaaaat tagaagatga aataccagaa
    10081 agtgttattg ggattgtcaa ttctgacaag ttaatgaact atgtttattt aattacttta
    10141 aaagaaactt ttgatgatgt tttagaagtt ttaaaagaat ttaatttttc agtggtttca
    10201 ttaccaaatg aagaaggtac accgttacaa gctatcaaga aatacaatga aatgataatt
    10261 agacaggaaa acgtttctaa ggacaaaaca gaggaaatta aaagacatgc agatagtata
    10321 cacatgcttg aaaacctata tgatttttac actatagaaa gagaccaaaa aaagattata
    10381 gagagacttg tcaaaacaaa aacaacattc tgtcttaatg gttggttacc aagcaaaagg
    10441 gcagatgaat taattaaaga aattacagaa aagtttgatt gttgtgttca gactgaagaa
    10501 ggaagtaaag aagaaggctt cccaattctg cttgaaaaca ataaattagt aacacctttt
    10561 gaaagtgtaa ctaacatgta cagctatcca agtacaaaag atattgaccc aaatacaatt
    10621 ttaactttct tctttgttat attctttgga atgatgctaa gtgacgccgc atatgggtta
    10681 ataattgcag tagtttgtgg atttgttgta tataaattaa agatacaaaa aggtgaagga
    10741 aatttaatta aacttattgg tatctgtgga gtttcaacta ctgtatgggg tcttatattc
    10801 gggggtattt tgggggattt aattcctata aaagcattaa ttaatccttt agaggatgtt
    10861 atgacactta tgggaatgtc gttactgttc ggtattatcc atatatatgt aggtttggga
    10921 ataaaagcat atacattaat aagaagtgga aaggtaatag atgcaatctt tgacataggt
    10981 ttttggtatt tgtgtataac aggtgtatgt ctacttataa taccttttgt tgcaggggac
    11041 ataggtgtat tttcagaagt aggaaaatat ttagcaatta taggtgctat aggtcttgta
    11101 cttactcaag gaagaagctt taaaggtatt cctgttaagc tttttaaagg attttcaagt
    11161 ctctatggta taacaagtta ttttgctgat atattatctt atacaagaat tatggcgctt
    11221 tgtttaacaa caggagttat agcacaagtt atcaaccttt taggggctat agctggtccg
    11281 atacttgcag ttgtaattgg tgttgtagga cacacaataa accttcttat aaatgcacta
    11341 ggtgcatatg ttcatacaag taggttacag tatgtagaat ttttcaataa gttttatgaa
    11401 ggcggaggag ttccttttgt tccgtttaag tataaaacaa aatatacaag cattaataaa
    11461 aaggagatgt aaatatggaa tttttaaacg cgttaggaaa tggtcaattt ttggcaatat
    11521 caggagctgc tatagcagca ttatttgcag gtatgggttc tgctaaaggt acttcaatag
    11581 caggtcaagc cgcagcaggt gttgtaacag aagaccctag taaattcggt caacttctag
    11641 ttttacaact tcttcctggt acacaaggtc tgtatggatt tatcatagct ttccttattt
    11701 tatcaaaagc agggattatt ggtggagatg caataccaac atcagctcaa ggtttacaac
    11761 ttcttatggc aggacttcca attggtttag ttggtttagt atcaggtata gcacaaggta
    11821 aagcagcagc agcaggagtt ggaatagttg caaaaagacc tgaagaactt ggtaaagcta
    11881 taacatttgc agcaatagtt gaaacatatg ctcttttagg actacttgtt tctttcttag
    11941 cttacaatgg aattgcaatt ggttaattat aaattataat tcataagtaa aaaaaatgaa
    12001 aaggaggaag cactcctatg ggtaatgaac aaaaaatgat tgacagaatt atagctgatg
    12061 ccaaacaaga agcacaagaa atattggata aagctaaaag tgaagcagat ttaaaagtaa
    12121 attcagctaa tgaaaaagct gaaaaggaaa tggcttccta tacaaagctt gcagaggcag
    12181 aagcagaaaa agcggcttct aaggaaatat caggagctta tatggaggct aaaaagcaaa
    12241 tattatcaaa aaaacaagag attttagaag aggtaatttt agaagctaaa aacaaacttt
    12301 taaatcttaa agataatgaa tatgaagaga ttatactaaa catgattgaa aaatcaaatt
    12361 gtacagatga ttcagagata gtattatcta aaaaagataa aaaaacatta aaagatgtgc
    12421 tatcaaaaaa aggcattaaa gtgtctgatg aaactagaga tattactgga ggtttcatag
    12481 ttaaaaaagg tgacattgag tacaattatt catttgaagc cataattgca gtagagcatg
    12541 aatatattga acaaattgca gcagaaattt tgtttaatta aggaggggtt aaaaaatggc
    12601 agaagaaaaa acttatccct atgccgttgc acgaataaga gtgcttgaaa aacagcttct
    12661 taacagacaa atgtttattc aaatggcaga agccaaaagc cctgaagact ctttaagaat
    12721 tatagctgag gcaggttatg ctgatacatc aaataataat atacataatt ttgagaatat
    12781 tttgactcaa gaattatcaa agacatatga aattcttaaa agtctagctc ctgaagaaaa
    12841 atttgttgat gtatttcttt ataaaaatga ctatcacaat ttaaaagtgc tgattaaaga
    12901 agaaatttct ggtgtagatg gtgagaaata tttaattgat ggaggtacaa ttcctcttat
    12961 taagcttaga gaatctttag caaatcgtag ttttagtgat ttacctaaga taatgtcatc
    13021 agctatatta gaggcatttg atgtttataa taagacacaa aatggccaga tggttgatat
    13081 tgttctagat aaagcaacct ttaccagtat gaaagaaact gctaaagaaa gccaaaacaa
    13141 atttgtaata gattatgtta tgaaagtttg tgatttaaca aatctaaaga gttttataag
    13201 agtcaaaaat atgaagaaag attttgatat gtttatgaat gtgtttgttt caggtggctc
    13261 acttgataag gaaaaattct tagaagcttt ttcctcagat actccagcat catgttttaa
    13321 atctacttct tactctgatg tctgtaaaaa tggcatggat agtggtttta ctgtctttga
    13381 aaaactttgt gatgactatc ttatggaata tgttagagga gcaaaattta agcctcttac
    13441 attagaacca ctaattgcat atttatatgc taaagaatca gagataaaaa caattagaat
    13501 tattttgact agtaagctta ataatataga cgcagatact ataaaagaaa ggctaaggga
    13561 tgcttatgta taaggtagga gtagttggag ataaagatag catcatggga tttttagctc
    13621 ttggaataga tatcttccca gcctatgata gtgacgaaat taaaaaaagt atacataagt
    13681 tggttgaaga tgaatatgcg ataatttata ttacagaaca ggcatcattg cttgcaaaag
    13741 aatcaatagc aaaatacaaa gattaccaac ttcctgccat tatagttatt ccaggtattg
    13801 gaggaagtat gggattaggt atgaatgaag taagagaatc tagtaaacgt gctataggtg
    13861 cagatatatt atttaaagaa tagatgaaag ttgaataaaa gacaatctca aattttattg
    13921 gtgctaaata tatgtgctaa taaaatatag gagggaatat ttaaattttg ataaagtata
    13981 tgattgcagg tgagagaata tgaaaacagg cacaattgta aaggtgtcag gaccgcttgt
    14041 tgtagcggag ggcatgagag atgcgaatat gtttgacgtc gtaagagttt cagataaaca
    14101 tcttataggc gagattatag aaatgcatgg agataaagct tctatacagg tttatgagga
    14161 aacttccggt ctaggaccag gggaagaagt agtttctctt ggaatgccta tgagtgttga
    14221 acttggacca ggtcttattt caactattta tgatggtatt caacgtccac ttgaaaaaat
    14281 gtatgatatt tcaggtacta atataactaa aggtgttgaa gtatcttcac ttgatagaac
    14341 aactaagtgg gaatttaaac ctaaaaaatc tgttggtgat aaggttgtag caggagatat
    14401 aattggtggc gttcaagaaa cagcagtagt agaatgtaaa attatggttc cttatggagt
    14461 taagggtact ataaaagaaa tatattctgg tgaatttact gttgaagata cagtttgtgt
    14521 tattacagat gaaaaaggta atgatatacc tgtaactatg atgcaaaaat ggccagttag
    14581 aaaagaaaga ccatatagag aaaagaaaac accagattca cttcttgtta caggtcaaag
    14641 agttatagat acatttttcc caatcacaaa aggtggggta gcagctatac cgggaccttt
    14701 tggaagtgga aaaactgtta cacagcatca gcttgctaaa tgggcagatg cagatatagt
    14761 tgtatatata ggctgtggcg agcgtggaaa tgaaatgaca gatgttcttc ttgaatttcc
    14821 tgaattaaaa gacccaagaa caggcgagtc acttatgcaa agaactgtgc ttatagcaaa
    14881 cacatcagat atgccggttg ctgcacgtga agcttctata tacactggta ttacaatagc
    14941 tgaatatttt agagatatgg gatatagtgt tgcacttatg gcagactcta catcaagatg
    15001 ggctgaggct cttagagaga tgagtggtcg tttagaggag atgcctggtg aagaaggtta
    15061 tcctgcatac ttaggttcac gtcttgctca attctatgag agagcaggaa aggtaaattg
    15121 tctaggtatg gatgaaagag aaggaacact tacagcaatt ggtgcagttt ctcctcctgg
    15181 tggtgataca tcagaacctg tcagccaagc aacgcttcgt atagtaaaag tattctgggg
    15241 tcttgatgca tctttagcat ataaacgtca tttcccagca attaactggt tgactagtta
    15301 ttcactctat caggaaaaag ttgatgtatg ggcagataaa aatgtaaatg ataatttctc
    15361 agctcaaaga gctcaagcta tgaaactttt acaagttgaa tctgaacttc aagaaatagt
    15421 tcaattggtt ggggttgatt cactttcaga tggagataga ttgatactag aggttactcg
    15481 ttctataaga gaagacttcc ttcatcaaaa ctctttccat gaagttgata cttatacatc
    15541 acttcataaa caatatagaa tgatgggact tatattaaaa ttctataagt cagcacaaga
    15601 tgctatcaag caaaatgtta ctataaacga tattatcaag ctttcagttc ttgaaaagat
    15661 tggtcgtgct aagtatgtag aagaaggcga tatagatgca gcttacgatt caattgaaga
    15721 tgaaatagac aacgagcttg cagaccttat taaaaagagg ggggctgaag aactatgata
    15781 aaggaatata agtcaataca agaggtagcc ggtcctctta tgttaataaa cggcgtagaa
    15841 ggtgtaaaat ttgatgaact tggagaaatt gaactttcaa atggagaaat tcgtcgttgc
    15901 aaagttctag aggtaaatgg agatactgca cttgttcagc ttttcgaaag ctcaacaggt
    15961 ataaaccttg ctgaaagtaa agttcgtttt ttaggaaaga gtcttgactt tggagtttca
    16021 ccagatatat taggtcgtgt ttttagtgga atgggtagac ctattgatgg aggtccagaa
    16081 attataccag ataaaagact tgatataaat ggagctccaa taaatccagc agcacgtgat
    16141 tatccggccg agtttataca aactggagtc tctgctatag atggacttaa tacattggtt
    16201 agagggcaaa aacttcctat attctcaggg tctggtttgc cacatgccaa tcttgcagtt
    16261 cagattgcaa gacaggcaaa agtacgtgga actgattcta agttcgccgt tgtatttgct
    16321 gcagttggta taacttttga agatgctgaa ttttttataa gcgattttaa agcaactggt
    16381 gcaatcgacc gttctgtagt gtttgtaaac cttgcaaatg acccagctgt agagcgtgta
    16441 tctacaccta gaatggcact tacagcagca gaataccttg ctttcgagca agatatgcat
    16501 gtacttgtta taataacgga tattacaaac tatgcagagg cattgcgtga agtttcagca
    16561 gctaaaaaag aagttccagg acgtcgtgga tatccaggat atctttatac tgaccttgct
    16621 actatgtatg aaagagcagg aaaaatgaaa gggcatgaag ggtctataac tatgattcca
    16681 atacttacaa tgcctgagga tgataagaca catccaattc ctgaccttac aggatacatt
    16741 acagaagggc aaattatact tagccgtgaa ctttataaaa aagatataca gcctcctata
    16801 gatgttttac catcactttc tcgtctaaaa gataaaggta ttggtaaagg taagactcgt
    16861 gaagaccatg cagatacaat gaaccagctt tttgcagctt attcaagagg taaggatgca
    16921 aaagaactta tggctatact tggtgaatct gcactttctg agattgattt aatgtatgct
    16981 aagtttgcag atgaatttga gaaagaatat gtttcacaag gatttagaac tgatagaact
    17041 attgagcaga cattagaaat cggatggaag cttcttagta tgttaccaaa aagtgaactt
    17101 aaacgtatcc gtgatgaata ttttgaaaaa tatatgccta aggagtgata tctgtggcta
    17161 gattaaatat aaatccaaca cgtatggaaa tgactagact taagaaactc cttaaaactg
    17221 ctacaagagg tcataagctt cttaaagata aacttgatga acttatgaaa caatttcttg
    17281 agattgtaag agaaaataag cgattgcgtg aagaagcaga aaatgctctt gatactgctt
    17341 ataaaaactt tataatcgca agagcagtta tgagtcagga gtatctgggt tcagcactta
    17401 tgatgccaaa gcaatcagtt tcagtagatg tttctacgag aaatataatg agtgttgatg
    17461 ttcctgtgtt tgactttaaa actgaaaaca atcaaagtga tatttatcct tatggtcttg
    17521 cttttacatc aggtgaatta gattctgcta tggaagcttt ctcagatgct atgcaaccac
    17581 ttttaagact tgcagaaagt gaaaaaagtg cacagcttct tgcacaagag atagaaaaga
    17641 cacgtagacg tgttaatgct cttgaaaatg taatgatacc aaattacatt gagactatta
    17701 agtatatagc tatgaagctt gaagaaaatg agagagcaag tactactaga cttatgaagg
    17761 ttaaggatat ggtgcttaaa aaagcacttg aagaaaagaa aaaaaatgat ttggttgtat
    17821 aattaaatac ttataaaaat aagtctaaca ttctacttta tagaggttag acttattttt
    17881 tatgtttaaa ttaaaatgta gatactataa aaattaatat attgtttaaa aacagactgt
    17941 atttaactaa aaataatata tttaacaaaa atttctaaaa attaacgaac tgttaattta
    18001 cacttaactt tatattaaca aattaggtgt attatataaa cataagcaaa aacaataaaa
    18061 aacaaataaa aaaaggaaaa aacacaaagg gggaagatat gaaagaattt atatttactt
    18121 gtctgtgcat tgtagtgatt acatttatga caagttgcat atcaacaaca ccacaaacta
    18181 ctcaaggaaa aggaaataat aaacttacaa tatatgcagc actagaggaa gagcagatag
    18241 cttattatat ggaaggtttt agagaagagt atcccaatat agatgtagag atagttatgg
    18301 attctcatgg tgtaatagct tcaaaactat tagcagaaaa agataatcca caagcagata
    18361 ttatatgggg attatcagca atgaacatga tagagctaaa aaaagatggt gcacttgaag
    18421 catataagcc taaaaattat gataaagttg ataaaaaatt taaagatact gaagatgatg
    18481 tatcttgggt aggaatgagt gtcccagaga cagcaatagt agttaattat aaggaactta
    18541 agaaactagg tatagatatt ccaaaaagtt atgaagattt aataaaacca gaatataaag
    18601 gacttataac aatgccaaat ccagcatcat ctggaacggg gtatcttaca gtatcagggc
    18661 ttattcaaat gatgggtgaa aaagatgctt acaattacat ggataaatta cataaaaata
    18721 tagccacata tacacactcg ggttcaaaac ctgcgaagtt agctggctct ggagagtatc
    18781 caataggtat tacacttgga tatagagcta cacaacaatt atctagtgga gaacctatag
    18841 aggttgtatt tccaaaggaa ggttcaggtt gggacttaga agcaaatgcc ttagttaaaa
    18901 aagataatat aaaaaaagaa gcaaagctat ttttagattg ggcaataagt gattcagcta
    18961 tggatagata tgcacatgaa gtagcagtta cttccataaa gacagataat ccagttccaa
    19021 aaggttattc taaacaacca tttgaacagc ttataaaaga agttgattta aactctgctg
    19081 ccaaaaacag aagtacagta cttaaaactt gggaatcaaa atacggttca aaatctgaaa
    19141 gtaagtaaag tttaaattaa taatttagat gaaagaattt tagaagaaaa agtaggatat
    19201 aaaatttaaa ataaaaaaat aactatataa ggagagataa gatatgagtt acttaaaaat
    19261 aaataatgtg tttaaaagtt atgaccaaaa aaaggtttta aataatatta gtttggatat
    19321 tgaagaaggg gaatttctat gtttactcgg acctagtgga tgtggtaaaa ctacattact
    19381 tagaataata gcaggtcttg aagatgtaaa tagtggaact ataattctcc aggataaaga
    19441 tattacaaat ttagagccat caaagagagg ttttggtata gtatttcaat catatgcatt
    19501 atttccgaat atgactgctt ataacaatat agcttttcca ctaaaagaga gaaaagtttc
    19561 aaaagaaaaa atagataata aagttaagga agtacttgaa acagttggat tgactaatga
    19621 agctcataaa taccctaaag cattatcagg tggacaacaa cagaggattg caatagcaag
    19681 agcattagct cttgaaccaa agtttttact tttagatgaa ccaatgtctg cattagatgc
    19741 aaaggttaga cacaagctta gaatggacat taaaagatta caaaaagaac ttaatataac
    19801 gacaataatg gtaacacatg accaagaaga agctataact atggcagata aaatagctat
    19861 tctaaatgga ggagatataa tgcaaatagg gactccagaa gaaatatacc aaaatcctca
    19921 aaacctattt acagctcaat ttataggaga tacaaactgt tttgataatg gagattctat
    19981 attaactgta agaccagaat atgttcaaat agagaaatcg acaaaagaaa actaccaagg
    20041 gataatatca aatatagagt ttagagggaa tttattgaga gttgaaataa aagataaatt
    20101 aaatgaaaat ttcataataa gtgatgtttc tataaaagag tgggttaatt taaatttagt
    20161 agaaggtgac cttgtaaaaa taagtataga cgaaaaatac tatttaaagt atccaaaagt
    20221 taaaggagca taagtgtatg aataataatg ctataagttc taaaagtata agtcttaaat
    20281 caaaaatgaa tttagatata aaaaaatgta tgcttacagt attagttatg tctttagtaa
    20341 tatttttatt agcacctata atatatctat ttgtacaggc ttttttagat aaagatggag
    20401 tctttgtagg attacaaaac tttcaagaat acttggcttc tgaatctcta ttaaattctc
    20461 taaaaaatac agtatttgta tcagttatat caactgtaat atcactaaca cttgcattag
    20521 tatatgcata tgcattaact agaacaaaga ttaaatttaa aggttttttt aaatcattag
    20581 ctatgtttcc tatgtttgct ccaacaatga tgcatgcaat aggtctagta tatttatttg
    20641 gaaatcaagg tttggtaact aatttacttg gagtgcatgt tccaatatat ggagcagtgg
    20701 gaataatatt ggcacaaatt atatatgtat ttcctcaatc atttcaaata ctttatatat
    20761 ctctaagttc aaccgattat agactatatg aagctagtaa tactatgggg ataagcaaga
    20821 taagagaatt tataagcata acaatcccaa gtataaaata ctctttaata agttctgcat
    20881 tcgtatcgtt tacattatgt tttacagatt ttggagctcc aaaggtgata ggaggagagt
    20941 ttaatgtatt atcaatagat gtatataagc aaattatagg gcaacagaat atgccaatgg
    21001 gagcaactgt atcaatatta cttttaatac ctgcaataat atcgtttata gtaactaaaa
    21061 aaattgaaaa aaatcaaaat tcatatataa cttcaaagtc aattccatat aaggttaaaa
    21121 ctaataagtt aagagatagt attttaggag gggttgtagg aattattgca tttggtataa
    21181 tagctgtaat gttaactgta atcttatctt cattaatatc agtttggcca tatgatttaa
    21241 gactgacact ggaacatttt tctatgaaaa acagtattga tgggattaaa ccatttataa
    21301 attcaataaa aatgtcacta tttacagcta ttctagggac gagctttgtt ttcttatttg
    21361 catatttgaa tgaaaaaaca gaaaaagctc catatttaaa atcatttggg tattttttaa
    21421 gtacattgcc tatggcattg ccaggattag ttttaggtat agcttatgta ttatttttta
    21481 ataaattaga gtttaatttt atggatacaa tatacattaa gaatttgttt aatggattat
    21541 atggaacatt acttataatg gttatatgta atatagttca tttcttttca gtagcattta
    21601 taacagctac tactgctatt aagaaagtag ataaagaatt agatatggta gctaaatcaa
    21661 tgggaataaa cagcgcatca attcttaaga acgtaactat accactttgt ttgccagcag
    21721 ttttagagaa ctttatgtac tttttcctaa actccatggt gacaatatca gcattagttt
    21781 ttatatatac tgcaagttca aaagtagctg caatatcaat tgtacaacta gatgataagg
    21841 ggagtactgc acaggcagca gcactagctg tgttaatatt agtcacaaat atattagtga
    21901 aagtaatata tgaatttata aagaatcgtt tagaaaaaag aacaaacttt aattaaataa
    21961 tttatcttat aaaaacacaa atttaaaaaa gtctattctt gtgatttatt atttaaagaa
    22021 tagacttttt aaatttatta ttgatattgt ttattaattt tccttttgtt atcatacatt
    22081 tgagaatctg cacgacgata tgtatcaaat aaagaaacat ctactttttc atcaaaaata
    22141 gcatatccaa tagacattga taattttaat tcattagttg agttttcttc aactattttt
    22201 aaattaatat tatttataat attatttatt tctttgtgag ataaattttt tagaataatt
    22261 atgtattcat cacctccaat acgataaact atatattttt tatttattac atattgtata
    22321 attttacttg cttgcttaat atataagtct cctgtctgat ggccaaattt atcattaatc
    22381 ttttttaaac cgtctaaatc tattgatatg atagatatta gattctttag atttgaattg
    22441 tttaagttat tcatatctat ttcaaaagca tttctatttt ttaggcctgt taaataatct
    22501 gtattagcaa aatcagtata tgtaggatta gatattcttt taaatagaat cactgcaatc
    22561 aatgctgata ttagacaagt taataatgct attattggtg taactatact tataaattta
    22621 aatgtattgt attgatgttt tgcttcaaat tcaattccta ttactccaac aaccttacca
    22681 acatcattgt gaataggaaa atacgatata aatatgtatc cccaagatgt tgatttaatc
    22741 tttttaggta acaatatatg attatctaat gctttgttaa ggtctcccca aatctctttt
    22801 tctatcaaat caccagcatt tctaaaatca ctcctagatg aatttaaacc atcaacaaca
    22861 tatactagtg atccatcttt tgttttttta gcagtatata gatacatgac tccagtagta
    22921 ttttttacag attctaaaag gattttagaa cttttataag acttttttga ttggtcttct
    22981 ttagaattaa tttcagtaaa ggtattttta tcaatatttc tttctacata ttcatagata
    23041 tgttttgacc tctcacttaa agagtatatc atgctcttat aagttagtgt ataattaaaa
    23101 aaatatacac atgaggaaga tattattaca ataattgcag taagtattga aacctgcata
    23161 tcaactctat tgaatttttt atttattttc atagcttaaa tgtcttgtga aaagaacctc
    23221 ccacaatctc cccataatta atatatatct ataaatttca ccataatata ttcatatatt
    23281 atcaaatttg tgtggaaatt acaattagta aacatgctta aagcattcaa atatagtttt
    23341 tttattatta tagtatacta ttttatgtat aaataaaatt atatataaat cattgatatt
    23401 ggttgtttat taatggaaga taccgtataa aatattctaa ttggttacga tatgtatact
    23461 taattgaagt taagttaagg gttagaatat gtattgatga aatggctaga tttatattca
    23521 taagtattaa ttttatcata gataggtaaa atactgtatc ttaaacataa gtatgattga
    23581 gatgcaatcc tgagatatga taatataaat tgaaggatag tgaactcaat caaataaaat
    23641 gattaatcta gctatataag caaataaatt taatataaaa gaggtggaaa atgaaagaca
    23701 gacttaattt aacagaagga agaattacag aaaaattact taagctatca cttccaataa
    23761 tggggacttc atttatacag atggggtata acatgataga tatgatatgg gttggtaaag
    23821 ccggaagtaa agcagtagct gcagttggaa cagctggttt ttttccatgg cttgcaatgg
    23881 catttattat gatttcaaaa gtaggtggag agataaaagt agcacaaagt attggtgcaa
    23941 ataatataag cactactaaa tcatatatga agtcagcaat agaaataaat attatactag
    24001 caataatata tacaatttct ttaatagtac ttaataaaca attgataggt ttttttagat
    24061 taggagactt agaagttata accatgtcta gacagtattt gataatagta gctctaggta
    24121 tggtatttta ttttattaat ccagtattta ctgcaatttt caatggtctt ggaaatagta
    24181 aaactccttt tcgtattaat acagtaggat taataactaa tattatactt gaccctatat
    24241 taatttttgg atggggattt gctccaaaac ttggtgttgc aggagctgct attgcaactg
    24301 tatttgctca gatagtagtt actacatgtt ttatatatat aatagttaaa agtaaagaag
    24361 aatattttaa attaagacta tttaaagaaa tagagactaa atattataaa gttctgtata
    24421 aattgggatt acctatagca atacaaagtg gtatgtttac agtattctca atgctattag
    24481 gagtaatagt agcatcatgg gggcctgtgg ctgttgcagt acaaaaagta ggctcacaaa
    24541 tagaagcaat ttcctggatg acggctgaag ggctatcagt tgcattaggc agttttgttg
    24601 gacaaaatta tggtgccaag aagtattcta gaataaataa aggttgcaaa atagctataa
    24661 ctgtatcttc tgtacttggt ataataacta ctttagtatt agtgtttgca ggagagagta
    24721 tattttctat ttttatagat gaaagtgagg caatagaaaa aggagcagtt tatcttaaaa
    24781 tattaggcta ttctcaattt tttatgtgtt tagaaataat aacaacagga gctttcaaag
    24841 gattagggag aacctatata ccttctatta taattactat actgactggt gcaagagtac
    24901 cattggctta ctttatatct agaccagaaa tgttgggtct aaatggtgta tggtggagta
    24961 taaccttatc aagtatatta aaaggtatat taatgataag tctatttata tctttattaa
    25021 aactcggaaa gttgtacaag atttctgaat aaaatttaaa ttatcttaaa tgtatagaca
    25081 ttttctttgt ttgtatataa aattatctta ttatataaaa gatttaataa ggagtgaatt
    25141 aaatgaaaga gccaatttat aaagttatag aaaatcatgt tagagagtta ataaattcag
    25201 acagtttgaa agaaggggat ttaatccctt ctgaaaaaca gctgagtgaa gaatttaatg
    25261 taactagaat gactgtaagg tctgcactta ataatctagt taaagaaggc tatataacta
    25321 gacaaagagg tgtaggtagt atagttattg caaataatat atatgataat atatcgtctg
    25381 taagtggatt tactaaagag atggaaagta aaggctataa agtatctaat atattggtat
    25441 ctcttgaaat agttcaggca gatgaaaatt tatcaagtaa gttgaatata agtttagaag
    25501 aaaatgtttg ggaaataaaa agagtaagat tagccaatga tgcaagagtt tcatatatga
    25561 ttacttatat gccagttaag ttatttccaa atttaaataa gactcattgt gaaaattctc
    25621 tttataattt tgttgaagaa gtgtgtgaat acaagatagc catgtcagag agagaagtac
    25681 aagctgtaat atcgaatgaa gagtgtatgg ataatctaaa attagaagaa ccagagccac
    25741 ttttatatat aagccaaatt tgtaagttac aaaatagtga gatttttgag tactcacaca
    25801 catatcacta tggatataca ttaactttga atgctgttgt cgaataaaat ttaaataaaa
    25861 tgaaaaagtt ttcttgaaat gtatatacat ttggtatata ataatatcaa gaattaaatg
    25921 tatatacatt taaaaataag atatatacat taagaaaaaa ttaatagaaa aacatatttt
    25981 aaatgtatag tttaaaaaac ttatgactta aaaaatattt aatgaatcta atttggaggg
    26041 gaaaaaatga taaaaataat gttagcttgt tcagcaggaa tgtcaactag tttattagtt
    26101 acaaaaatgg aggatgcagc aaaggaaaac ggtatagaag caaaaatatg ggctatatca
    26161 gaagtgaact taaaaaatga aatagaaaat tgtgatgtct tacttttagg gcctcaagtt
    26221 agatatgtat taggaaaagc aactgaaatg gcaaaaccat ataatattcc agtagaagtt
    26281 ataaatatga tggattatgg aagatgtaat ggaaaagctg tgttagatag agctgtagag
    26341 ttaaatagtt caaaataaag ttgtactgga ggatgtaaaa tggaaaaatt catgtcattt
    26401 atggataaat atatagtgcc tgtagctgct aaaataggag ctcaaaggca cttagtagca
    26461 gtaagagatg catttatagt aatgatacct ataactatgg taggtgcatt gggaacattg
    26521 ataaataact taccattgga agcatacaaa aatttgatgg caagtatatt tggagaaaac
    26581 tggaccacat ttggaggcga cctttggtgg ggagcaatag gtacaatggc agtattctta
    26641 gtaataggtg ttgcttattt tctagcaaaa tcttatgaga gtgatgggtt acaatctggg
    26701 cttatagctt tatctatctt ttttataatg gctccacaaa ttggtaaaat agttcctgag
    26761 ggaggaacta cagtagttga aggatgggga atgatacaac aaacctactt aggtacagca
    26821 gctttattct cttctatatt aataggatta ttatcaactg agatatttgt aagattatct
    26881 aaggtaaaga aattaactat aaaaatgcca gatggagttc caccagcagt ttcaagatca
    26941 tttgcaaagt taataccagg aatgttaact ataatgatat ttactgtaat aggaatattt
    27001 ataaaaatgc tttctaatgg aagtttctta acagatattt taaatactta tttaggagca
    27061 ccactatcaa atgtagctga tagtctaggt tctacaatgc ttattgcatt tataattcat
    27121 atactttgga ctgttggact tcatggtgca aatatagcac ttccttttac agaaactata
    27181 cttatgaaat taggtggaga aaatgctgcc ttggctcaag caggagcaac ggaaggatac
    27241 catgtacttg caggtgcatt ctttgatgca tttgtatatt taggtggttc tggaatggta
    27301 ttgggattaa tagtagcttt attaatagct ggaagaagac gtaaagagat gatagtatta
    27361 ggtggtccac ctgcaatatt taacatagga gaaccattga tatttggact tccaatagtt
    27421 ttaaatccta tatttatgat tccatttgta cttgcaccag taatatgtag tgctgtatca
    27481 tacttagcaa tagattttgg attagtagca ccagtaattt tacctaaaat accttgggta
    27541 acacctccta tattaggtgg agcaatggct acaggtgact ggactggcgg agctttagca
    27601 ctatttaatt taatattatc aatattaata tatattccat ttgtcatagc gtctgaaaaa
    27661 atggaagcta ataaattgaa aattaacaac taggtagttt tatttcggta aataaatgta
    27721 tagagtttta aataaatgta tggggttttg tagagtatat taaattatag gtaaggatgg
    27781 tataatgaga tgaaaaaggg actaaaaata gttacaattg gaggaggttc aagttatact
    27841 cctgagcttg tagagggttt tataaataga tatgaagagt tacctgtaaa ggaattatgg
    27901 cttgtagata tagaagctgg aaaagaaaaa ttagagatag ttggaaatct agctaagagg
    27961 atggtaaaaa aagctggagt agatatgaaa ataaatctta ctttagatag aagagaagct
    28021 ctaagagatg cagactttgt gacaacacaa cttagagtag gtcttttaga tgcgagaata
    28081 aaagatgaaa ctattccttt atctcatgga gttatggggc aggaaactaa tggtgctgga
    28141 ggtttattta aagcccttcg cacaatacca gttatatttg atataataaa agatgtggaa
    28201 gaattatgtc caaatgcatg gatggtgaat tttacaaatc caacaggaat aataacagag
    28261 gctgtattca aatatactaa ttttagaaga tatataggtc tatgcaacgt gccaattcat
    28321 ttaaaaaatg atgttgccaa actatttaat gtagaaagtg acagaataag tatggatttt
    28381 gcaggtctta atcatatggt ttatggtcta aatgtatctt tagatggaga agatgttaca
    28441 aaagaagcaa ttgataaatt tgtcaaagca gatataagta tgcaaaatat aaaggcaatt
    28501 gattttaatg ctgaatttgt aaaatctttg ggtgcaatac cttgtccata ccatagatac
    28561 tactataaaa ctaaagaaat gcttgaggat gagttgagag agtttaaaga gggaaaagct
    28621 agaggtcaag tagttaaaga attggaagaa caattatttg aattatataa ggatgaaaaa
    28681 ttagatgtaa aaccacctca acttgaaaaa agaggagggg cttactatag tgatgctgct
    28741 tgtaatttaa taagttctat atacaatgac aaaaaagata tccaagtagt taatacatta
    28801 aataagggtt ctataagaga ttttaaagat gaacaagcag tagaagtaag tagtgtaata
    28861 acaaaaaatg gtccaaaacc aataagtata ggatatttac cagattctgt gcatggatta
    28921 gtaagtcaaa tcaaatcatt tgaagtattg gcagctaaag cagctgtata tggcgattat
    28981 gaatctgctc ttttggcact ttgtataaac ccattgattc catctgatga cttagcaaaa
    29041 actatattag acgaaatgtt ggaagctcat aaagattatc ttcctagatt taatagatag
    29101 ttgtctatag aaagtaggtt atggtatgac taaaattata ataaatgcag atgattttgg
    29161 atattgtgaa gctgtgaact atggaataat ttcagctcat aataatggta tagttaggtc
    29221 tacttctatg atggcaaata tgcctggggt agaacatgga gtaggcttac ttaaagaaaa
    29281 taaaacttta aattgtggag ttcatatgac tttaagttgt ggtagaccat tattatctaa
    29341 cttaaaaact attgttgata aagacggttt ttttattagg aggattacag acgaaattat
    29401 tgaaaaaatg gattgtgatg agatttatag agaactttgt gctcaaatag atagggtaaa
    29461 agggcttgga atagatatat ctcatttaga tagtcaccat catatccata ctttagtaag
    29521 tttaaagcca gtaatagaga agattgtaac caagtataat cttccaataa gaggtggatt
    29581 tgaatataat ttagagtatt ctaaagtagt tcctttaata gatagttttt ataaggaaaa
    29641 tgtaagtgaa gaatatttta taaaaaatat agacgaaata atgaagtatg atgtagtgga
    29701 tattatgtct cacccagctt ttttagatga ttatatttta aattctacat cttatgctat
    29761 tgatagaacg aaagagcaca agatacttac atctaaaaaa gtcaaagaat ttttagaaaa
    29821 gaatggatta gtcatatcaa gctatagaga tatttaggag gtcgaataaa tggatgagaa
    29881 gatgatagag atatcttttg gaataattgg atttgcaggt gatgcgaaag ggctagcatt
    29941 tgaagcaata aaagaagcaa agagcgggaa tatagataaa gctagagaat gtattgaaaa
    30001 gtcgaaagaa tcaattcata aagctcataa attccaaaca gaattgatac aaaatgaagc
    30061 taatggtaat aaaactgaaa taagtgttat acttattcat gcacaagacc atttaatgac
    30121 agctatgaat tttcaacaat tagcagaaga atttatagat gtatatgaaa gattagaaag
    30181 taagtaattt aaaattatta ttaaaaaaga gtgtataaaa ataattttta taattattaa
    30241 atgcactctt tttttattta agtagagttt agcaatatag tattatgtta ttgatacttt
    30301 agaatttaga cttctcataa ttgtaaggta tactagtacc aacaactaca tcttcaattt
    30361 tttcaacaat aagccaatca tccatatttc cttgatggtc aaaatcaaga ggtgttattt
    30421 cttcaacatt ttcaaattca actaagcata aacatttttt atgccaacga actttttgct
    30481 tttcagataa atttaatttt ggttgatttt catttaaaat tttagaaatt tcatcttctg
    30541 ttaatttaac atagttttct acctttttaa cagtggcttt tgcagatatt tttgcagttc
    30601 ctttttccat aaaataaagt aactcatctt caaatactct actatgtggt atttttctac
    30661 cagcagcacc tctaataacc attgtttttg ttccatccaa gattttatct aagacctttt
    30721 ctcctttttt tcctgcatta tcacaatata ctaaatgtac catgttttga atcctcccta
    30781 ctaaattcct tatctataaa ttgcatttta tcattgttta actgaaaagt cattgtattt
    30841 gtgtccaatt cttaaaaaaa atactgttta atataagaaa accttatcta agctatatat
    30901 aattaagatt aattaggaat ttttatcctt ttacaaaata atattgacta aaaatagaaa
    30961 aatgctataa taaatatgtg cttatgataa tcaatatcat gtaagtataa taaacaagta
    31021 ggagaagtaa tcatgaaaaa aataaaatca cttgcaatat ttatatctat tataactacg
    31081 ttagtacttg ttacagcatg ttcagataag aatacagagg ataaagataa atcagagaca
    31141 agagttgtac aatctgttaa aggagaggtt aagataccat caaatcctaa aaaaatagtt
    31201 gatatatcag gaagtagtga agaactatta ttagcaggtt ataagcctgt tgcaacagca
    31261 aatgtagact catatgaaac tgataaatta ccaagttaca taagagaaga gcttaaaggt
    31321 gtaaagatag ttgggcactc aatgatggat actatggata tggaagctat attagaagta
    31381 aatcctgatt taataataat gagtcaaaga caagaaaaaa tatatgacca attaaaagaa
    31441 atagctcctg tagttatgat gaaagattat gcaaatgact ggagaagcaa gttaactgat
    31501 gtttcaaagt tatttgacaa agaagaagaa gataaaagtt ggctacagaa gtatgatgaa
    31561 aaagctacaa agttaggtaa ggaagttata gaaaagaatg gagaaaaaac ttatttacca
    31621 gtgttggcaa gttcaggtca atttatggta tttagtgatg gtggaatagg tactctaatc
    31681 aatgatgata tgaaattagc tagacctaag aatatgccaa aacaggatgg aataacacta
    31741 ccaatggtaa gtatggaagg tttaacagat atagatgcag accatatagt tgtaattgct
    31801 acagaagcag ataaaaaaga tttagaaaat agtgctatct gggctcaaat aagagcagta
    31861 aaagatggta atgtaacaat acttgatgct gctccatttt tcagtcaatc atacaatcca
    31921 attggaaaag agttattatt agaatcagtt aaaaatgaat taacaaagta attcttaact
    31981 tagtaggtgt gagataatga tattcatttt tcacacctat ttttaataaa tcttaaaatt
    32041 aaaatactta atagatgata ttatactgac gattaaaagg gaaaaggagg taggataatt
    32101 gactaagctg agtaaaaaaa atataactta tttgttgata ttagtaagta tagttgtact
    32161 tgtatttgga attgtattat ccataactat tggggcaaaa gatatgaatc tatcaactgt
    32221 tatagatagt ttgataaaaa tggaagatgg aataaatatg agaatagtaa aggatgttag
    32281 acttccaagg gcaatagcag ctgcacttgt tggagggttt ttagcagttt ctggggcaat
    32341 aatgcaagga ataacgagaa atcctatagc tgaaccatct gttataggaa ttacacaagg
    32401 agctacattc gcaatttcga tatcactggt acttcaaaaa aaacttcctc aacttataca
    32461 tggaagtttt agtgtaatga tgtttgcatt tattggagca agtataagtg gattatttat
    32521 atattttata agttctaaat caagaggaag agttaataat gtaaaattag ctcttgcagg
    32581 agtcgctctt ggtacattgc taatttcttt ggcatcagca atatctatgt attttaacct
    32641 atctcaacaa ttaagtttct ggatatcagg agggcttgta ggagtgaagt gggaaggtat
    32701 aaaattgcta tttgtagctg gtggtattgg atttatttta gctattatta tggctccaag
    32761 aataactata ttaagtcttg gagaagaagt ggcaatagga ttaggacaaa aaactaagtt
    32821 tgttagattt atatgtatag tacttgtaat attaatgact ggagcatctg tgtcagtgtc
    32881 tggtaatatt atttttatag gtcttatagt tcctcaaata gctaaaggaa tagtaggttc
    32941 agattataag tatataatac cgagctcttt agtattagga gctgtattgc ttgtatatac
    33001 agatatatta agtaggatga taaatcctcc atatgagaca ccagtaggtt ctataacagc
    33061 acttatagga gtgccaatat ttatatacct tgttagaaag ggggagaaat aggtactatg
    33121 aaaaatatta taaaaataaa ttctaaaaca ttacttgtta tatcaatttt aatggtgctt
    33181 atttttatca cttttttatt gagtttaaat atgggctcat tttctataga accaatggat
    33241 gttataaaga cttttttagg gcagggtcag cgtaatcatg aaattgcaat atttaaatta
    33301 agattaccaa gaatagtaat agcacttttg gttggttctg cattatcaac agcaggtgta
    33361 atacttcaag gagttacaaa gaatgattta gctgattctg gaattttggg aataaattca
    33421 ggtgctgcat tgtttgtagt agtttatata taccttatga atggtaatgt atatgaaggt
    33481 atgagtaact tgactgtatt tacaatgcct attgttgcac ttataggagc tttatttgga
    33541 gcatttctta tatattctct tgcatggaaa ggtggtataa attcgtcaag attactactt
    33601 attggtatag gtgtaaacat agcttttact tcaattttga cgatattcca attgaaattt
    33661 acaacacaag aatttaatag ggttatggca tggacatcag gaagcatttg gggaacaagt
    33721 tggaaatatg taatagctgt gcttccattt atagtgattt ttatgggtat aactatttat
    33781 aaatctaaat atatagatgt tttaaatttg ggtgatgaag tatctataag tcttggtgta
    33841 gatgtagaaa aacaaagaag aagacttata atatatgcag taattttatc tggtgtatcg
    33901 acagcagtag caggtagtat ttcattttta ggtttaatag ctccacatat aggtagaaaa
    33961 ataataggac caaagcataa aagattaata ccagtatcag cattgatagg aacattatta
    34021 cttttaatag cagatactat atcaagaaat cttctagcac ctatagaaat accagtaggt
    34081 atagtagttt ctataatagg agtgccgtac tttatttatt taatgttggt aaatgattag
    34141 gaaagggtgt tgttatgaac tgtataaata ctaagaatct aaatgtatca tatggaaaca
    34201 cagatattat aaaaaattta aatttaaata taccaaaagg aaaaataact accatcatag
    34261 gggctaatgg ttgtggaaaa tcgacaatac ttaaaactat aggtagaatt attagcccta
    34321 atagtgggaa aatatatata aatggagagg acatctacaa aaagaagtct aaagaaatag
    34381 caaaagatat ggctgtactt ccacaaagcc ctcaagctcc tagtggtctt accgtttcag
    34441 aattaatttc ttatggaaga tttcctcata aaagtggatt tggtaattct agtaaagaag
    34501 acagagagat tgtaaattgg agtttagaag ttactggaat tgcagaattt aaggatagaa
    34561 atatggaaga tttatcagga ggacaaagac aaagggcatg gatagctatg gctttggcac
    34621 aagaaactga tatattatta ctggatgaac ctacaacata tttagatttg gcacatcaat
    34681 tggagatact aaaattatta gatgaactaa ataaaaaaca aggaagaact attgtcatgg
    34741 taatacatga acttaataat gcagcaagat ttgctgacca catgataggt attaagaaag
    34801 gtaaaatagt ttgtgaaggt gatgcatatg atgttatgac gaaggataat ctaaaagaat
    34861 tatttaatat tgatgcagaa atagcaacag acccaagaac aaataaacca atttgtataa
    34921 cttatgacat ggtgtaaatg gtgacaacat ggagaatcaa gaagcattaa gacatgaaaa
    34981 aatatggatt ttattattta ggtattcgat acctgcaata atagcaatga tggtaacttc
    35041 actttataat gtagtagata gagcttttat tggttctatg gaaggtattg gctctatagc
    35101 tattgcaggt cttggtgtaa ctatgccagt atttactcta ataatagctt ttggaatgtt
    35161 ggtatcagta ggtgctagca caagattgtc tataaagtta ggggaaagaa atagagaaga
    35221 agcagagaag atattaggta atgctttgac attatctata attatctctt taattataac
    35281 tatattagga ttagttttct tagaagagat actttttatt ttgggtgcaa gtaaagattc
    35341 aatattttat gcaaaagact atatgagtgt catattggtt ggaagtatat ttaatttagt
    35401 tgcattttct cttaataatg caattagggc agaaggtaat ccaaaattag cagcaaggac
    35461 aatgattgta ggatgtgtat taaacctgat attggaccct atatttatat ttgtatttaa
    35521 tttaggtata aaaggagcag ctatagcaac agtactctgt caaatagtag tatttttttg
    35581 ggtaatacat tattttataa gagggaagtc caatttaaaa ctaaaaaaat gtaacttaaa
    35641 attgaataaa gatatagtaa agaaggtatt tgcaatagga atgacacctt ttgctatgga
    35701 agtagctata agtataactc acatgtttac aaataattct ctaaaggttt atggtggaga
    35761 tttagctatt ggagctatga cagcacttac atctatttta ttgatgttta tgatgcctgt
    35821 gtttggattg aatcaaggta tgcaaactat aatatcatac aattatggtg caaaacaata
    35881 tgagcgtgca aagaaaactt taatattatc tatcatagtg tcagttgtca tattgtcatt
    35941 tggattttta gtagtacaag ttttcccaga agtatttgta ggtatattta ataaagattc
    36001 agatttgatg gatatagcag taagaggtat aagcctaaat ctaattacat tgcctataat
    36061 ggggatttct attgtaggac ctgtgtattt tcagtgtata agtaaagtta aacattcaat
    36121 gtttttaact cttttaagac aatttatttt atttatacca ttaatcattg tacttccaat
    36181 tcaatttaat ttagatggtg tttggttggc acagccagtt gcagatttta ttgctatgat
    36241 aatcgtatta ttattcttaa aaagggaatt taaaacaagc cgagtgtaag aaatttagaa
    36301 aataaaatta aattggaaaa taaaaagact tgtctttata aaatgattaa aattatttta
    36361 tagagacaag ttttttattt tatttaaacg gaactatcca tactggtttc ttctagtttt
    36421 tttccaaaag tcattttctc aaatatttct tgaggtagag gttttgaaaa aacatatcct
    36481 tgtatcatat cacaattaat ttttttaaga taatccattt gcaagattgt ttcaacacct
    36541 tctgatatac tattcatatt taattttttt gccaaattaa ctatagattc tattacatga
    36601 ttttcagcaa tattatctgc attaggtgag ctaaaaaaag cacggtcaag ttttaatgtg
    36661 tcaactttta tttcttttaa catattgagt gaagagtatc cacttccaaa gtcatctagt
    36721 gaacattgaa aaccttcttc atggatttgg tctattatat taattaattt ttggagattt
    36781 tcaaatacaa gtgtttcagt taattcaatt tctaagagct tagcaggaat gttgtattta
    36841 ttacgaagca ttctgtattt ttctaaaaaa tctatattat ttaaattagc acgtgaaaaa
    36901 ttaactgaaa caggtattgg agtttctcca ttatctatcc attttcttat catactacat
    36961 actttttcaa aaacatagtg gtcgagtttt gtaataaaac catttttttc aaagaaagga
    37021 ataaactcgt ctggtggtat aaggccttta tttgggtctt gccatcttac taatgcttct
    37081 gcacctacaa tagtattatc tttgaggctt attttaggct gaagatatac tataaattcg
    37141 ttattattta atgcttcctc cattctattt tccatttctt tttctttaat catttttaaa
    37201 cgctctaaat cactataaaa aacacatgta taaagtggat gatttccaat gtttccttta
    37261 ttattttttc gtgcaacatt tgcacggtct tgaattgaaa ctaaaggtag atttgggtca
    37321 tcaattttat atacacctat agatagagct ataaaatatt tacattcttc atttttattg
    37381 aaactattaa tatcattggt gatattttct atgtacttaa gaatttcttt ttgaggaata
    37441 gttttaataa gtacattaaa ctggtcatta gaaactcgac aaagcaattc tcctggttct
    37501 agataattac taatgacatc atgtatgtac tttaatgttt tatctcctgc ttcactacca
    37561 aaagaatcat taataagttt gaatttctga atatttatag ataccaatga atagctttct
    37621 gatgaagatg actgtataat ttttttagct tcaatatcaa aacgtgcttt actgtaacct
    37681 ttagttacag agtctacata ggcgattttt ataagttgtg ccctgttttt ttgatttata
    37741 aacataatca atataataag caataaaaat agtataacaa ttaaaatatt gatgaagatt
    37801 gcttttttta gaagtaaatc aaactgtgca cttgctgttt ttgttggaac aattgaaagg
    37861 aggtataagt tttcttcttg taatggaaga tagtgcattg ccttagaaat accatcattt
    37921 aatgtataat acatagaacc agttttgttc ttttttaagt ttattttcat ttcttcaagt
    37981 ttatttttat caacctgttt tccttggtgt ttaatcatgt caaaaaaatt taccacattt
    38041 tttggagcat ttttgtttgc tgaacttaca ataaaatttc catcttggtc gataatttgg
    38101 gaaaatcctt caccatgaaa gctttctaca cttaataaat ttctcatagt atcaatagta
    38161 ttccaagcag caacagctcc aacaatttta tcgccattgt atagtggtac agaatataaa
    38221 attccatatg taccagattg tgatttaaca ggagtaattg tttctttgcc ttgaagggct
    38281 tttctataaa agtcttgtcc tttaacatta cctgtatctt taagggcact tacaaaattt
    38341 ccattagaat ctataatacc taaccaatca aattcaaata attttaattt ttttgataag
    38401 tatctattga cttctttttc actatcatta atctcaaaat aagtatctcc catagaatat
    38461 agtgtcctaa atatactttt acatttcaca ttaattgtag tggaaatacc ttgtgaaact
    38521 tctacaagat atcgttctgt ttcattatgt gttactttat ttagattcat aataaaagtg
    38581 acacatgtta atgacacgat taaaagaagt gtcaatagta aagtagctat tattttttta
    38641 ttttttgtgt tttcaaagtt cattcttttg tttcatcctc catcctttat ttgtttacaa
    38701 ataagaattc tctcagacat attataccaa atatcttttc atacaaagat attaaatttt
    38761 atttatccca ctttacattt agctttattt atgtcttctt agagattaat caagatacgt
    38821 ttattgttta aatcttattt tataatattt tgagtaaaag aggttaaaaa aagaactgtt
    38881 ttcaaaataa ttttgataca gttccttttc agtatagaaa atttttatag tattagaaag
    38941 aacttttagc ttatgtatct acataagtat tatatttata aaagatattt tgttacaatc
    39001 taaaatgtag atgaaattct gtaaatgcca aattctctat gaccaagact ttcagctttg
    39061 gtatgtttac cattacagac ttctattatt tcattaaata tttcttgacc tatatctgct
    39121 attttagcac catctgttat aattctacct gcatttatat cgatattgtc tggcattttg
    39181 ttgtatgtat cactattccc agtgatttta ataactggtg aaatagggct tcctgttgga
    39241 gtacctctac cagttgaaaa gattacaatt tgtgcaccac ctgctaccat accagtgata
    39301 gaatctatat cttgacctgg agtatccata aaatataatc cttttttatc aggaggtaca
    39361 atatcagcat attcaagagc acctttgaat ggcttattgc ctgccttata catacaccca
    39421 agtgactttt cttcaattgt tgaaagtcca ccagttttat tgcctggagt aggttgacca
    39481 ctacgtaaat cttctcccat agcaattgct cttttttcta catcacttac aaatttaaga
    39541 aacttatctt tcatttcttc atcttcaaaa cgggtagcca acaaatgttc tgcaccaatt
    39601 acttctgtag tttcacttag tatgctactt ccaccttcat ctacaagaag gtttgatgca
    39661 acgcctattg aagggtttga agctattcca cttgttgggt cagaaccacc acattcaagt
    39721 gctaatgtaa tttcactcat accaaattca actcttactt cttttgatac ttcacgagcc
    39781 attttactta ctatttcagc tcccttagaa actgttttta atgttccgcc acattcctgt
    39841 ataacaacgt aatctacctt ttttcctgtt gtagctattt cagatgctaa ttcttttgct
    39901 tgaataccat cacatccaag accaactact aaaactgcgg caacattagg attttttcca
    39961 aatcctatta atgtctttgc tgtaagctct atatcagaac caatttgaca acatccatgt
    40021 tgatgaggga ttgctattgc tccaggcaca agtgatgcta ttcttgtagc tgtctcactt
    40081 gaacatacag atgttggaat aattaaaaca tgattacgaa taccaaactg accattttct
    40141 cttaaataac ccattaattt cattttaact tcctcctatt ttttatctcc acgaccacgt
    40201 gtactttcaa tgttatgtac atgaacatag tcaccagttt ttatgtcaac tgttgcaatt
    40261 cctataattt caccgtattt gtatacaaca tcaccttttt ttacatcttc tgtagccatc
    40321 ttatgaaaga ctggtatatt atcatttact atgtaagatt ttccatcaat tgaaactttt
    40381 tcacctttaa ctaaaggtct gacacatgta actagattat ctttttcatt tgcatgaata
    40441 attgcattca ttaattttac ctccttaagt attaatttac ttcaatattt ttatttgttt
    40501 taaaaataga ttttttcttt ttttctcttt tatctagata ggaaactaac attggacaac
    40561 atattgctgt aacaataata gcagcagcaa cctgtactgt tgaaacagct gctattgtag
    40621 ctagagtagg gtctatagct gctaaagctt caggagtacc agctgcattt ccggctgttg
    40681 tacctgtagc tgcacctact gctggatgtt ctgcacgtat aagtttcatt acaaagtacc
    40741 cacccatacc tgttattata gtaactccta aaccaagtac aactccaggt agtccagcag
    40801 ttataatttg attaaagttt aatgctgctc ctaaaggaaa agcgaagaaa ggaattaata
    40861 atgttgtacc aggtgcaaga aattctcgta tatcttcatc aaggttacca agtataaatc
    40921 caagtagtat tggtataagt gctgcaaata gtgctattat aggtacattt gcaagtccag
    40981 ttactccaaa agcaagcatt gtaaaaaaag gaccatcatt tagagataag atagatattg
    41041 ctccaacatc tgtggagtct ccatattcac ctgcaagagc agcaaataga cctccatttg
    41101 aattagtcat ggtagcaact atggcaagag gtgtaatacc aattatacct ttaggtccaa
    41161 taaatttact aacaataata cctaatactg caccaattat aaattttgtt gctgtaagta
    41221 ctataccttt agtcaatggt ttaccagctt gtctgatatt gatttgagct ccattgcata
    41281 gacaaaatag agcaagtata ctcattgcac cagttttaaa taaggatgtt gtgaatcctc
    41341 caatttcaag agcttgtgga catactgtat taaatagtgc tcccaataac aagggacaga
    41401 ccataagtcc tcctggtatc tttttcactg attttaagat gtgcatctag tatcactccc
    41461 tttcattttt atataggtat tataaaagca attaatatgc caatatatag agtttgtatc
    41521 tttagttatc atgattattt ttaataatcg attgaaatgc tgtagattac ttataattaa
    41581 aagtacgatt gacgagaatt tcacttacaa agattctttt tatcatataa ttgtattttt
    41641 tattgaaaac aaataaacgt cttatgtatt aaaattaaac ataaaacgtt ttgatatata
    41701 taggtatgta ttatttttaa acatcatctt ctatttcttt taacttacgc catagagtgg
    41761 agcga
//
LOCUS       DAEPKC010000024        40987 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.024, whole genome shotgun sequence.
ACCESSION   DAEPKC010000024 DAEPKC010000000
VERSION     DAEPKC010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 40987)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40987)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40987
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.024"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            339..1175
                     /locus_tag="KR294_001365"
     CDS             339..1175
                     /locus_tag="KR294_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBH0239447.1"
                     /translation="MNIKKIFNNNVVVSSLEDGTEIIVTGAGVGFKKKVGDLIDENLI
                     SKKYFVQDDQRDKYNQILNKTSIEYFKISEEIIEKANEVLNTQVNDSIILALTSHIEF
                     AVQREKQGIKLPNLILNETKQLYREEFEFGLWAIDEIEKRIGIKLPEDEAGYIAIHII
                     NGLENSQKDEGINILEFSKQVIQIIEEVHGFKLDVNSLNYTRLITHLKFFVQRILRKE
                     TYNDSDIEDMYKLVNKNYNKPKVCTEEIAALVLDRFEYKISKEEELYLMIHINKITNS
                     GC"
     gene            1528..3105
                     /locus_tag="KR294_001366"
     CDS             1528..3105
                     /locus_tag="KR294_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBH0239448.1"
                     /translation="MKKNKLGLWNFFQMLGKTFMFPIALLSVSGMMLGLGAGFTDPKM
                     IEMVPFLGNEYVNLVLNFMLTIGLFAFNNLGALFAMAIPLGLLKKEKEFGAFSGLVGF
                     IAMHIGTNFYLTRADLLVPAEQMSTNGQAMIMGIQTYNTSVLGGIVAGLIVYAIYDKV
                     SNLKIPESLGFYSGPRLVPIVSLIVMSIVGLLIPIVWPPFFNAFQSLGRWISSAGPLG
                     YFSYAVAERVTIPFGLNHLVTSVFRFTPIGGTAVIDGETYFGTLNMFMAYVENNQIIP
                     LDLAGKMEQGKLMIQYGLAGAALAIYRTAKPENRKALKGLLISGVLTVIIGGISEPIE
                     FLFLFISPALFAFHTFMNGIANMVLPYLGVLMGFTGDLIAFISFGVLRGTATGWPIAV
                     LVAVLYFAIYYFVFKWAIIKFNIKTPGREDKEIKVSEGNGSDFKNLSTYKGQQMISAL
                     GGQSNILSLDNCVTRLRLKLQDVSLINEDAIKEAGGIAVVKLDEHTIQVIIGTQVYSL
                     RKQMDKAMEGHLEACND"
     gene            3098..4282
                     /locus_tag="KR294_001367"
     CDS             3098..4282
                     /locus_tag="KR294_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PatB family C-S lyase"
                     /protein_id="HBH0239449.1"
                     /translation="MINFDKKVDRLGTYCTQWDYVEDRFGKKDLLPFTISDMDLEFPF
                     EITEVLQERLNHRVLGYSRWKHDDFRNSVTNWYIKRFNCSVDSNWIYYSPSVMYSISK
                     LIEMLSNEGDGILINTPAYNAFYDVIINNNRNIIKSHLVNRNGFYSIDFNDFEKKCKK
                     SKIFILCNPHNPTGRVWSELELVKMIGICKNNDVKIISDDIHMDIVYDNRMTPILNVA
                     KDYLDSVFICTSASKSFNIPALTGSYVIIPNEGIRNKFENITRYRDFVNSPAILAILA
                     TMVCYDDCEYWLDELLKYLKENLKYTIDYIKDNLEPLKLVMPEGCYFAWIDFSELKIS
                     GEKFQKLLMDIGEVAIMSGSVYGEEGEFYLRLNVACSREKLEDGLNRIKKTMDYIAKR
                     IL"
     gene            4300..4899
                     /locus_tag="KR294_001368"
     CDS             4300..4899
                     /locus_tag="KR294_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBH0239450.1"
                     /translation="MGYLKTMVDVMTTEMNAIRCLIDEAGIEYESIVSEIANCEGKVI
                     FMGVGKSAHIGKKLAATFASTGTPSFFVHATEAVHGDLGMIESKDITILISNSGNSME
                     VVNCIKYIKAIGSKTIAFTSNRNSVLAKECDYALIYPAKDEADHLNLAPTTSSTITLV
                     LGDSIACALSKSSNFGSSDFYKYHPGGSLGEKLKTANNG"
     gene            4923..5393
                     /locus_tag="KR294_001369"
     CDS             4923..5393
                     /locus_tag="KR294_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBH0239451.1"
                     /translation="MFKMFKKKSIKSPISGKVIELSKIQDGVFSQKIMGEGVAIDSTG
                     DIVYAPINGKIVVVAETKHAFVIELENGMELLIHVGLDTVNLKGEGFEVLVSMGEQVK
                     EGTPMLKINRPLIESKGISLITPVTITNHSEYNMNTCNVGNSVEGGKDTVIEFK"
     gene            5765..6511
                     /locus_tag="KR294_001370"
     CDS             5765..6511
                     /locus_tag="KR294_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HBH0239452.1"
                     /translation="MKIENLSIDDIKRGYIFNDDLNCYSCIKCTKTYEVGEIYKIGNR
                     FFEASKAIELHMELEHSDYLEQLLNSDSKYNTLTENQKQLFQLFISDLPDKEIAKQVG
                     VSTSTIRHQKFIFREKAKQAKLYLALYESVFEDKSNKSSTIIPIHEHARMVDERYVVT
                     EEERKHILDTSFESMNPLKLKVFSSKEKKKVVILSKILEQFERGKKYSEKEVNQILES
                     IYDDFATIRRYLIEYGFMSRNKECTKYWLT"
     gene            6572..7246
                     /locus_tag="KR294_001371"
     CDS             6572..7246
                     /locus_tag="KR294_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase"
                     /protein_id="HBH0239453.1"
                     /translation="MNDELKSILYNKGVDIVRFVDISEFPINQTQGFSKAILFCIGLS
                     KKFITDIYNNLPTDSDEFLEKEEKVEELADWISKYIQNKGYRAYSQSEKNNLEHGYFE
                     KAYINPEMQSGISPLPHKTIANISGIGFMGKNNLFVTEEYGCAFSMCTVLTDAPISVE
                     RYPLIDSKCMDCNVCVENCPAKAIHGNEWTLPGKRESIIDVSKCFCVLRCMMSCPWSL
                     RYANQK"
     gene            7615..8961
                     /locus_tag="KR294_001372"
     CDS             7615..8961
                     /locus_tag="KR294_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 55 protein"
                     /protein_id="HBH0239454.1"
                     /translation="MEIETKTPDWINVLELNSKIDITGKYDVSNMIQNIVSDKSLEGS
                     IIYFPKGNYLFEKGIKISQQITLQGDSYYGGGNQVSNLDKKQSIIGTTNFITRGVSNM
                     SIITLSGTSQCIKNINFYYDSHDIEKIPPKNVSAITEYGETQGLSHFEHLFISGFSGI
                     GIEIPYYSTGNDITVSSCGLGMRLGEKSMLSSSKIYECKNGMEITTGVSLNNVRIEEI
                     KEIGINNKGFGFNLIMNLMVDQCGYCGFMFEKMCYSQITARITRCGQYYKSVDYNAYE
                     NMEDRKEEAYSIFYGDILENCNIVLMNSNIDTLENDSLDEHKIYVIKANETNNVMLTC
                     YAEADNFIQCAKGNLLLENGENTYKFYNGEICSVGGVQISDIDEKDLIKIIENTLYID
                     DKGKYLMVPRLKKNTVIYSVLDSTEEINKLHGGIWEQIDVKVLAGESMYYYKKIKD"
     gene            8988..10388
                     /locus_tag="KR294_001373"
     CDS             8988..10388
                     /locus_tag="KR294_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239455.1"
                     /translation="MEESIIIKDISGWINVLDYGICNDETKDVSFKLQEIMDAVPEDS
                     IIYFPKGKYLFESGVKIKKRLTLCGDSYILANVPKNTAGVTQFTFKGKKNPKSENIAI
                     ITAKSVRHCIKSICFYSDSCDRDMTSNHEPPTDGKPRFHHNVIINYRNISAIVCEDKQ
                     GESGHYKNLSFSGFSGIALDMPNNSTANDITIFTSGLGISTGENSTIANSKVWGCVDG
                     MIISTGTFINGMRVEEIKKVGIKNIGRGLNFITNITIDQCGYCGVWFDSISNVQISGN
                     ITRCGQYYYDVSYDNYLMLDNRVKEAYSLFYGNLLESSNIVLSNTNKDNWEDFKEDKH
                     KVYLVEALETKNVLLTCNIDATDWIVKSEKGNLTYNNMRQTVIFYDGKLSSINGIGIS
                     DEDYGDKVKIKKGNIYINSKDKDIKMHKPEVGDIMSTIIKDKSILSAHYGGTWEKIGE
                     KIEFGITVHYYKLIEK"
     gene            10598..12034
                     /locus_tag="KR294_001374"
     CDS             10598..12034
                     /locus_tag="KR294_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 55 protein"
                     /protein_id="HBH0239456.1"
                     /translation="MEGRTGIKDGRWINVVERGIKNDGSYNVGPALQDIIDEIETDFC
                     VLYFPKGKYLFTSGVKINKEIVLQGDSNSSTGTTQFITRGVENMSIITLTGKKQCIKN
                     INFYSDSCEIQVNKEPPTKGNPKYHYEMIINKNEKNVEMNNVSAILYDNSKNMIKGLG
                     HYENIYISGFSGTGIRIPYYSIVNDITVSSCGLGIDTGIDTIISNSRISKCQNGMRIR
                     TGTSINNVRIEKIQKVGLISSQVKGYEGYGSYKINNITIDQCGYCGFSFDSMKDSYFS
                     GIIRRCGQYYYNTDYDTYLSIKDRVEEAYSLFYGNYFTECNIDLVSDNKDNWDDGLEY
                     KHKVYVFKTLQIPKLTLRCNIDAYDYIVKSVHGGGNLMLKNNFNNYIFIDSSNPEVIN
                     GINFNYQKNGNLLRLNNGKLSYKNGKEETAIFRPNYGLIVASTDSECEQIETSYGGKW
                     EKLGSEVIGEETVYYYKHHEPDKTNQIQ"
     gene            12378..13322
                     /locus_tag="KR294_001375"
     CDS             12378..13322
                     /locus_tag="KR294_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1848 domain-containing protein"
                     /protein_id="HBH0239457.1"
                     /translation="MIVSVSRRTDIPAFYSKWFFNRLKEGFVYVINPMNPKQVSKIEL
                     NPHTVDCFVFWTKDVTPMLYDLNKLKDYKYYFHYTITSYGKEVETCILDKRKVIDSFK
                     ELSRKIGKERVILRYDPIFLSEKYTVDYHIKAFASLCNQLDGFTEKCIISFIDLYKKT
                     KFNTKALHIKPIEITEIETLSKEISKIAHKHGITLEMCSEEYNLSKFGIGKSKCIDDR
                     LISKIIGCEVEVKKDSTQRDICGCVKSVDIGQYNTCRHYCLYCYANFNYAKVEENCRL
                     YKEDNKLLIDTLRDDAKISIRDMKTIKVDKNKQISIFD"
     gene            13491..14423
                     /locus_tag="KR294_001376"
     CDS             13491..14423
                     /locus_tag="KR294_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HBH0239458.1"
                     /translation="MNLLKKYPIPIASLILSIFTLGNLLQSYSESLRNVIGFIGFILY
                     AIYIVKIILLRKGVKEQLENTLISSTFPTITMATMIFATYIKPLSLELSIMIWSIGIV
                     GHLVLIVLFSKKFLVKFSIKTVFPSWYIVYVGIVVASVTAPAFNQLLIGKIAFWIGFV
                     SYIVLIPVILKRVWIIKEMPEPSLPSIAILAAPGSLLLSGYINSFSDKNNVVLYLLFI
                     LSIVFYIIVLGYLPKLLRLPFYPSFAAFTFPMAISAMGMKLMNGYLTKSGHFISWISY
                     ASKLEEIIATVIILYVLVLFIIYLSKSETTSKAK"
     gene            14528..14995
                     /locus_tag="KR294_001377"
     CDS             14528..14995
                     /locus_tag="KR294_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C_GCAxxG_C_C family protein"
                     /protein_id="HBH0239459.1"
                     /translation="MKTKEEYLKEVRNISEEYFRKGEFFCSEAVLQTINDALGQPLSP
                     EITKLASGFPIGLGKAQCLCGAISGGEMALGIVYGRVHGEAMNPKMFEHAKGLHDYIK
                     KEYGATCCRAITKKWDGDNFMSPERKEHCIKITGQVTEWVADKLIEDEKLNIK"
     gene            complement(15239..16093)
                     /locus_tag="KR294_001378"
     CDS             complement(15239..16093)
                     /locus_tag="KR294_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009912760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HBH0239460.1"
                     /translation="MLTIIIALLPVMGWGLMPIVANLKKSSPHEQLLGTSISAFIFST
                     IITLVIHPEITFFSFCISMISGIFWSLGQLMQFKAIQIASVSKVMPISNGSQLTFTTL
                     LAVILFNEWTSSKMLLIGSLSILCIILGILLTNYQTKKSTDKNMLKCVGVVLLSSLFL
                     SLYVVTNQIFLIEGYRIILPQSVGMLITSSIIVKYFSKEIVYRENVLFNLITGILWSI
                     ANLGMFITTNTLGVTISFSISQSCVIVATLGGIIFFKEKKNKKEWLAIFIGIILIMSG
                     VFMLSIIK"
     gene            16259..18223
                     /locus_tag="KR294_001379"
     CDS             16259..18223
                     /locus_tag="KR294_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBH0239461.1"
                     /translation="MLTDMIQNREIKIIKFLLKEGHTTVKAIADDLDVSEKTVSKSLK
                     EVEAVLKKIGLSLIRKPKIGVYIDGDLKKILPYLDNKGSQIPTTREERVIYIYSVLLK
                     SNDYITIQQLSDELYISRGTIERDLAEVEKLLKNEGISIYKKPSKGIKLNISERDKRQ
                     LTAKFIHKFWSRNWYIKQEQESFYQAFEKIQADVNGIFSEDDLSIIIDILRNFSRERK
                     FEFSDYEFQSLVIHLAIAVERIRKGEYIEESLYTGNIENNQMSNTNYLAKQLEEKFSI
                     LLPKSEIGYINLHLVASDQHRDTNELKNTSTNPCETSTNNISNLREIIKNTLYETAYD
                     KDLIDGLTSHVHSSINRLKYGLSIKNPYVNTIKQNFSLSFEQALDLKKVIEFIYDIRI
                     NDDECAYIALHFEAFRERMKELPQNIRVILVCSTGLGSSRLLSARIKKYFPMIKIEKV
                     LSVQELVSSKIDADLVISTIYLELETIPTIVVSPILNESDIRTLERNIQNVSSCTSKK
                     YKSFRNLIFEENILLNIEASNYEDAIKYITDNLIKKGFAKEGIAKSAIERENLSYTSF
                     QSIATPHANPSYIKKSNISVATLKNPITWGNEKVEVIFFISLENDKNLELDEIYEVFY
                     DFIDNKKNINDILSATSTKEVYDLLVEESI"
     gene            18223..18684
                     /locus_tag="KR294_001380"
     CDS             18223..18684
                     /locus_tag="KR294_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH0239462.1"
                     /translation="MKISDVLKKEQIVFNLDTNTKEETIKKLSSIFVENGIVDNEEEY
                     VKSVLEREEHSTTGIGNGIAIPHGKSNAVKKSSIIFAKTKHKIEWDALDEKPVDSIFL
                     LAISNIDKDSNHLVLLSKLATKLMDDDNVDALKLANSEQEIINIFSEEGEM"
     gene            18687..19007
                     /locus_tag="KR294_001381"
     CDS             18687..19007
                     /locus_tag="KR294_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HBH0239463.1"
                     /translation="MKRKIIAVTACATGVAHTYMAAQALKKASKKMGHLIKVETQGAT
                     GIDNELTTKDAQIAEVVIFAVDTKVRNAERFEGKEILEVPVNAPIKDAEKVINDALKL
                     IDTK"
     gene            19023..20123
                     /locus_tag="KR294_001382"
     CDS             19023..20123
                     /locus_tag="KR294_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HBH0239464.1"
                     /translation="MLKKIVSELKKHVLTGISYMIPLVIAGAMIMAISRVGGSFYNIP
                     DIWDAKYAESASSIVRLLHDLDGFGGTALGLMFPVIAAFIGFSIADKLAIVPGLVGGM
                     IAKDIGAGFLGALAVGLIAGYTCLFIKNHVKLPKSAASIVPIFIVPVFGTLITVVLIN
                     YVIGIPFATLNTGLENWLNGLSGTNQILMAAIIGAMMAVDLGGPVNKAALTTSLALLT
                     SGIYAPNTAAMVGIVIPPLGLGLATILAKQKYNKQLREAGKSSLIMGLIGVSEGAIPF
                     AVESPLKVIPSCVIGTAIASAMAVGLGSVNATPISGFYGWFTVENWPMYVLSIAVGTV
                     IVAGLVIVLRGNPVIEDDEFEDDDFDEAEWES"
     gene            20243..22843
                     /locus_tag="KR294_001383"
     CDS             20243..22843
                     /locus_tag="KR294_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HBH0239465.1"
                     /translation="MIKAHIVNHTHWDREWYFTSGDALVLSEQLFTDVIDELERNPDV
                     SFVLDGQLSILDDYVQLHKEKIEIIKKLIKEDRLHIGPWFTQTDAFFARGESILRNLM
                     IGIFESKKYGKYMKIGYLPDTFGFNAQMPILLKHVGLDNIFFWRGIHLGKQVQSPYFK
                     WKSLNGESYIYAVNMPHGYGTGMLLEPSLKYVNGRLDPAIDFIKSYTDVDEVLIPSGN
                     DQLNIIGDFKNKIKAINDIGKYSYITSSYQEFLKYIKSIESLESYRGEFREPVLARIH
                     KSIGSSRMDIKLACDKLENKLIKRIEPLLVIAKKSKIEISNQLLINTWKKLLEGQAHD
                     SLAGCVTDTVTDDILHRIREANEICDSIENTIVKKISEGLKLSKNDILVFNTEAKRFN
                     GYKEIQVVSDSKNIYFKDNLDATIIEETYVKPRENVLEETPAGNIFIEEPGYYILKVR
                     INVQLPALGYKVVSFELSDKEMVSLDKSNDTFISNDNYKIIYEDGSLNLQLKDGTYIS
                     NFLTLKDSGNAGDTYDFSPLKNDENIKLSFDKVYTEKALGYEKMVVKGTTLLPLTLED
                     RKNKYLNGKLNVKVSIVLSKENPLMDVKLCVDNTIYNHRLRVHIKTDIKDNKNIASLP
                     FGYITRKNGVLDNWEDIYSEMPIDLEPLESNITLTNQNRSCTVFTRGIKEYQHIEDEI
                     ALTLLATTDELGKPDLLYRPGRASGDTTKKGHIRIKTDKAQMLKELEFSFAIYMDSKS
                     FDELEIANLTHNYLRECVNYQLQDYNFFLYHIDNKIQKSIVNKTVSRELEIISLPENY
                     LISACYPSYYSKDKFIIRVENPSSNRMILDEQIFKNRNGKIVNAIEDVEEEQVYEIAP
                     FDVISILLDL"
     gene            23312..23647
                     /locus_tag="KR294_001384"
     CDS             23312..23647
                     /locus_tag="KR294_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0239466.1"
                     /translation="MYNIDDMIYNCPVEALSNILGKKWVAIIIWKIQEDKKRFGELQR
                     AIPDCSKKMLVQQLDFLIEQGIIVNQKKLVNNVVESTYFLSESGLRLLPVMEKMIMWS
                     NKNLNCDKY"
     gene            23784..25061
                     /locus_tag="KR294_001385"
     CDS             23784..25061
                     /locus_tag="KR294_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HBH0239467.1"
                     /translation="MQNVNLFLVFIEGIVSFFSPCILPILPIYLSILSNSSVENLKEG
                     KTSFIGSSLFKNTIFFALGISTTFFILGSSVKVLSMFFNENKDLIMFIGGIIIIIMGL
                     FYMGIIKSSILNREKRFNVKFKEMKAITAFILGFTFSFGWTPCIGPILASVLVMVSSS
                     SNHLSANLLIAVYTIGFILPFIITAMFYSKLFKTIDKIKSNMEIIKKIGGIILIVSGI
                     LMMVNGFGSISKHFNTSQNSKIESKQEENKRENSTDKEENSDGNDSQKDSNNDNNDKG
                     SNDEDRIKSIDFTLTDQYGKTHKLSDYEGKVVFLNFWATWCPPCKEEMPYIEQLYKDY
                     NKNNDDVVILGVASPNLGREGSREHVVNFLKEQGYTFPVVLDEDGALAYQYGINAFPT
                     TFIIDKEGYVTQYIPGAMDKATMASFIENQRNK"
     gene            25182..26570
                     /locus_tag="KR294_001386"
     CDS             25182..26570
                     /locus_tag="KR294_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBH0239468.1"
                     /translation="MKKTFDAIIIGFGKGGKTLAGDLANRGLKVALIEKSNKMYGGTC
                     VNVACIPTKSLENSANSVKTKNINSWDEVQAEYEKAIDKKETLITKLREANYNKLNSN
                     ENVTIFTGMGTFIDEKTVQVKTENEIYELVADNIFINTGSRPFIPNIKGIENKNIVYD
                     SESLMNLRVLPKKMTIIGAGFIGLEFAGIYSSFGAEVTILNSNNGILPNEDVEDSEEI
                     IKLLAKRNVKIVNNANIKEIKEVSELAIVEYEVDGKSKELTSNMILVATGRKANTEGL
                     GLENAGIELNERGFIKVSETLKTNKEHIWAIGDINGGPQFTYISLDDYRIVINQLFGD
                     KTRTTNDRKNIPNSIFISPAFSRVGLNVKQAKEKGYEVLVAKMPVEAIPRAKQIGKAD
                     GFIKIVIDKKSNKILGASMICENSSEIIHLIQLAVDLEVEYTYLRDRVYAHPTMTEAL
                     NDILSPNMIKEV"
     gene            26774..27487
                     /locus_tag="KR294_001387"
     CDS             26774..27487
                     /locus_tag="KR294_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017208807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF434 domain-containing protein"
                     /protein_id="HBH0239469.1"
                     /translation="MNKISKRGFDDSDKRWFSSKELTRLIKAKEEIEWLLNRDYKIDP
                     VVTFVGDRYQFSIRQRDALKRAVCTDEKNIIRQSKRLSLDKIKEDTVNIDGFNLIISI
                     EVGLSGGTLVIGSDGNIRDLAGLRGTYKIIDKTEEALNLIGKFFNKYNAQNLKFYLDA
                     PVSNSGNLKYRILEHAKTWGIETEVELVKNADVVLEKLDRVVSSDAVIVDKCISYFNV
                     ARGIIEEYIKECNIINLNK"
     gene            27605..28474
                     /locus_tag="KR294_001388"
     CDS             27605..28474
                     /locus_tag="KR294_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HBH0239470.1"
                     /translation="MRGWICVKLTKLNIKKYRAPIYKYALANINLRSAKSTNSSIITV
                     IPQGAKMEVLDEEDDWIKVMYNSQEGYVYKELVSVSEYAWSNLNLREDKSTTSNIITV
                     IPEKSRVEVLQVDGDWSKVVYDDKIGYVFNYFLSIDGNKPNELDYKYFYTDMIKFVNE
                     NNIKSTSDYLIVTDLRNKYTYIFKKDNGGWGQLYKWQCTIGKPETPTITGIFYISGRK
                     PSFGTDEYSVKYATRIKGGYYYHSVLYDSTGSYIIDGRLGEALSHGCIRLSTENAKWI
                     YDNIPDTTTVIIH"
     gene            complement(28629..29774)
                     /locus_tag="KR294_001389"
     CDS             complement(28629..29774)
                     /locus_tag="KR294_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HBH0239471.1"
                     /translation="MSIYYVPPINLLGKGCLNEAKDSIKSLGTKKAFIVSDKFLVSNG
                     TVKKVTDILSQIDIDFVVYDEVKQNPTVTNVNKGLKILKSENCDFVITIGGGSPQDCG
                     KAISILATNGGDIRDYEGINKTSKKCLPIIAITTTAGTSAEVTINYVITDEDRHVKMI
                     MVDTNSLATMTVNDPELMISKPSNLTAATGMDALTHAIEAVVANGAYDVTDSTALYAI
                     KQIFKYLPRAVKNGNDIEAREQMCYACFLNGIAFSNAGLGNVHAMAHQLGGLYDLPHG
                     VCNAMLLPIVEEENAKSAPAKFRPIAEVIGMDVNNKSDKECVDFVIDKIKALSEEVGI
                     PKSLKDVGVDNPNFELLAENSMKDACAGANPVFFDKDKIIELFMKIS"
     gene            complement(30107..30883)
                     /locus_tag="KR294_001390"
     CDS             complement(30107..30883)
                     /locus_tag="KR294_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HBH0239472.1"
                     /translation="MTSDNHRPTARILDILEALAESENGYTLTEIADVINAPKSSIFP
                     IVHTLNARKYITIDKNTSKYSIGIRSYTLGSSFFEKRTIFNYIIDEMTNIVNSCSETC
                     QLGILDNNEVLYIGKVDSPEPIRLISYVGKKIPANCTGLGKALLCDFDKEKLISLYPD
                     GLKGFTEKSITDFDVLYDQLLEVQRTQIASECEESMEHLKCLAVPIRKNGCIRAAVSV
                     TLPLFRANDEKIELIKKLLLNAQKNIQSMMEERNEDIVIN"
     gene            31465..32439
                     /locus_tag="KR294_001391"
     CDS             31465..32439
                     /locus_tag="KR294_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-3-deoxygluconate permease"
                     /protein_id="HBH0239473.1"
                     /translation="MIMDFIKKIPAGMMIVPMFIAAFINTFCPDIVQIGSFTTAVFSS
                     VGSATIIGVQLVCLGTQLQFREMPKVLKRGGILLGSKFAIGALIGILIGKLFGMDGVL
                     GLTTLAVISAVTNSNGSIYLSLMTSYGDETDCATMSLLTLNDGPFFTLIALGTSGLAN
                     VPLLSLLAAIVPILVGMIIGNFDKKMKEFLEPGCNLLVPFVGFALGSSINLASILKGG
                     LSGVLLGLISVFVGGIFIVFCDKFIGKRPGYAGWAVATTAGNAIAVPAAVALVDPSWQ
                     PYVATATTQVAAAVVVTAILVPLITSWWAKKYGCPKFPKQNEDGTITA"
     gene            32537..32842
                     /locus_tag="KR294_001392"
     CDS             32537..32842
                     /locus_tag="KR294_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HBH0239474.1"
                     /translation="MINAVIIDEKDNVAVAIEAIAKGSEISFKLKDKTVKTITALDDI
                     TIYHKLAIKDMAKGDKVTKYGEHIGEANQEIKSGQHVHIHNVRSVREDLDKQVMTNI"
     gene            32998..34158
                     /locus_tag="KR294_001393"
     CDS             32998..34158
                     /locus_tag="KR294_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HBH0239475.1"
                     /translation="MKFYGYKRPDGRVGIRNHILILPTSVCASDTTRIIASQVQGAVT
                     FNNQNGCSQVHSDQQLTMDVMAGYAANPNVYGVIVVSLGCENCQNDLVVDAIKERTNK
                     PIKTLVIQEEHGTLKTIEKAVRYAREMAQEASLLRKEEFPISELILGTECGGSDPTSG
                     LAANPLIGELSDKLVDLGATSILSETTEFIGAEHILARRAVNEEVKEKILHIVHRYEN
                     SLKLVGEEVREGNPSPGNIAGGLTSLEEKSLGCIHKGGHRQISEVYDYAKQIDKKGLV
                     IMDTPGNDASSVAGMVAGGAQIVVFSTGRGTPSGNPIAPVIKITGNKITFANMEDNMD
                     FDASPVIYGPQTMEELTDDLLNMVVDVANGKQSKAESLGYTEMAIARVCNYV"
     gene            34208..35110
                     /locus_tag="KR294_001394"
     CDS             34208..35110
                     /locus_tag="KR294_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="HBH0239476.1"
                     /translation="MKFVSFTEGENECKRTGVFSKDELFIIDVNSLNLSRNFKDLNEL
                     IQNVSSEDIIKLKTIINESTFYNYDVFKRERCTVHVPIEKPIHDILCVGVNYKDHLEE
                     TQTHFDDSFEEPQKTVYFTKRVTKAIGPEDEIDGHFEINNQLDYEVELGVVIGKTGVN
                     IRKEEVEDYIFGYTVINDISARKLQKEHVQWFRGKGLDTFTSLGPCILHKSAVPFPIK
                     LKVCSRVNGEERQSSNTGLFISDVSDIVSELSKGMTLEAGDIIATGTPSGVGMGFSPP
                     RYMSSGDVVECEIESIGILKNYIK"
     gene            35190..36083
                     /locus_tag="KR294_001395"
     CDS             35190..36083
                     /locus_tag="KR294_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HBH0239477.1"
                     /translation="MKAEFLTPVVTIFDEEGNLDKEGNKKVYDHLIDGGVDGLVIMGS
                     TGEFFNMSMDMQKELIDLVTSHVNKRVKVFIGTSRMCINESIELSNYAHNSGADGVMI
                     ISPYYFSLDDDSIELFYSEIAKNTEAEIYLYNYPDRTGYDLSPELTLRLARKHKNIVG
                     YKDTVTLMGHTRDLINTMKIEFPEFKVYSGYDENFIHNLMSGGAGCIGGLSNLIPEVC
                     SKWAEAYNNRDMEKVIEIQKYINKAMDFYLITNPFIPAMKKAMNIRGLQISDYMTAPF
                     VKPNEKQVCEIKKLMNELNIC"
     regulatory      36136..36317
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            36545..37675
                     /locus_tag="KR294_001396"
     CDS             36545..37675
                     /locus_tag="KR294_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBH0239478.1"
                     /translation="MKFKSNVLKQFFLIAMVIFMVGGLIGCSKSDKENKQASTGKKLE
                     LKYASGFSVEDLEDGIKKVTDGDNRELILIPKKIKIPEKYKNANIVRTPVDNVLIAST
                     TQACSLRTIDELDSIKAVTTEEQYWTIKEIKDLMKDGKIHYVGSNLAPDYEKIVDLNP
                     DLTIVSSGLSEADTKFIDKLKELGLNYVVDNEYKEQNPFGRMEWTSLIAAFYDKEDMA
                     TSELNKTVQKVEEVSKKIKNKAKPKVVWASVYEGSAYIAPKDSYVDNMIKMAGGINAC
                     ASIDSNEGRVSIEQLHEVAKDADIFVYSSSSDYAPNLDSIKSSAPVLADLDVVKNGNL
                     WVFAPDYYQSVDKTDELIVDLVEMFHPGTTGEKIKHYINYDK"
     gene            37747..38772
                     /locus_tag="KR294_001397"
     CDS             37747..38772
                     /locus_tag="KR294_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HBH0239479.1"
                     /translation="MDFINKMRIRNTTIFIVLIISMILTFLVCVAFGSVKIEFKEVID
                     VVLRGMDNTEHYKIIYNIRIPRVLATMVGGACLAVSGILLQIFFKNPIVEPYILGVSS
                     GSTLSVALMILGGYTLGFESVNSMSIFVAAFIGALIVMSIVILFANKVKNITTLLIIG
                     IMTGYVCSGITNVLQSFANSDKLKEFTMWSMGSFSGFTWEKVEILIIVGILGLLMTVF
                     IIKPLNAFLLGEEYAKSIGINIRFFRVLIVFISSILAAIVSAFAGPIGFIGLAVPQIS
                     KMIFKTSDNRVLIPVVIFLGSIVTALCDLISRVILSPVELPISTITSLLGAPIVVMLL
                     VKRKDRA"
     gene            38775..39971
                     /locus_tag="KR294_001398"
     CDS             38775..39971
                     /locus_tag="KR294_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0239480.1"
                     /translation="MLKTNNLSVGYNNKVVISNINVEVKNGEILCLLGSNGAGKTTLL
                     RSLSKLISPIKGEIYLNGVNINCISRKALSKKMALVLTNRLLGDLMTVQDIVNIGRYP
                     YTGFFGSLSKKDLIMVDEALESVDALHLKKRYFDELSDGEKQKVLVARALVQEPEIII
                     LDEPTTHLDIKHRLELINILKKLSKEKSISVILSLHEIDIALKSCDKVALIKNNKVIA
                     YGQPEDVVDEDIINSLYELDDKNFNSLLGSVEISNKSKNEVFIIGGGGKATPIYRAFT
                     KKGIGLYSGIIHENDIDYEIGRTMGIKMFTENPFEPISDESFNLAIRNLNDSKIIIDT
                     GFSVGETNKRNIDIIKEALKLDKKVYSFRNRDESKKYYDSLDSKIEHIDKVSQIINSA
                     DINNLL"
     gene            complement(40099..40824)
                     /locus_tag="KR294_001399"
     CDS             complement(40099..40824)
                     /locus_tag="KR294_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HBH0239481.1"
                     /translation="MKTISKQELEKTLEKHYLWLKNNNAGEKADLKELRLENMDLRGY
                     CLSNIDFSWSDLINLNLEKADLENSIFNNSYLSDCSLKNSILKNADLSGASFRFCDLS
                     NSDIRGANLENSNLEHATLNGVISDESTRFFKLYCPETGAFIGYKKCFNFRMVQLLIP
                     SDAKRVSATSNACRCDKAKVLSITSIDGKESFKSARAYADENFIYRVGETIVAEDFNE
                     NRWKESTTGIHFFLTREEAIGYL"
BASE COUNT        15967 a         4344 c         7167 g        13509 t
ORIGIN      
        1 attagtacaa aactataatc ttaatttcaa taaatatata tataattaag ttgaaatact
       61 tgaaaatact ggaaaaaatt gaaaataatt tttgtaatat aaaatgtcga ttgattttaa
      121 ataattaaat atacataaga aataattaaa tatctttcaa tgaaaatatg ataaaatatg
      181 acaaattaat tgatgacaat aaaaaatatt ttgttattgt agtattatag ggtaaattgc
      241 aaaatatata cgaaagtaaa attttaaata ttgacattaa attaaatata ctatactatg
      301 taagtgtgat gagagaattt ttttagaggg gatttatagt gaatataaaa aagatattta
      361 ataacaatgt agtagtaagc tccctagaag atggcacaga aataattgtc actggtgctg
      421 gagtaggatt taagaaaaaa gtaggcgatt tgatagatga aaatttgatt tctaagaaat
      481 attttgttca agacgatcaa agggacaaat acaatcaaat acttaataag acctctattg
      541 aatactttaa aatttcagaa gaaattatag aaaaggctaa tgaagtttta aatactcaag
      601 tgaatgattc aataatatta gccttaacta gtcacataga atttgctgtc caaagagaaa
      661 aacaaggtat aaaattacca aacttaatat tgaatgagac aaaacaactt tatagggaag
      721 aatttgaatt tggattatgg gcaattgatg aaattgaaaa aaggatagga ataaaattgc
      781 ctgaagatga agcaggatat attgctattc acataatcaa tggtttggaa aattctcaaa
      841 aagatgaagg tattaatata ctagagtttt caaaacaagt tattcagata attgaagaag
      901 tacatggatt taaattggat gtaaattcat taaattatac tagacttata actcacttaa
      961 agttttttgt tcaaaggatt ctccgaaaag aaacttacaa tgatagtgat attgaagata
     1021 tgtataagtt agtgaataaa aattacaata aacctaaagt gtgtactgaa gaaattgcag
     1081 cattggtatt agacagattt gaatataaga ttagtaaaga agaagaatta tatttaatga
     1141 ttcacataaa taaaataaca aacagtggtt gttaggattg taactgataa agcaggcaaa
     1201 acctaagtca ttgagcttaa ctattagatt aagttttttg atttaggttt ttttattaga
     1261 tacaatcaaa atacagacag tgacttttag gattgtaact ggttaagcag gcaaaaccta
     1321 aatcattgaa tttaactatt aggttaagtt ttttgattta ggttttttta ttagatacaa
     1381 tcaaatacag acagtgactt ttaggattgt aactggttga gcaggcaaaa cctaaatcat
     1441 taaacttaat tattaaatta agttttttga tttaggtttt tctataaatt tgattatgtt
     1501 tttagataaa aataggaggg gaaaattatg aaaaaaaata agttaggttt atggaacttc
     1561 ttccaaatgt taggaaaaac gtttatgttc ccaatagcac tacttagtgt ttctgggatg
     1621 atgctaggac ttggggcagg ttttacagac cctaagatga ttgaaatggt tccattttta
     1681 gggaatgaat atgttaactt agttttaaac ttcatgttaa caataggatt atttgcattt
     1741 aacaacttgg gagcattatt tgcaatggca attccactag gattattaaa aaaagaaaaa
     1801 gagtttggtg ctttttcagg attagtagga tttatagcaa tgcatatagg tacaaatttt
     1861 tatttaacaa gagctgattt gttagtacca gcagaacaga tgtcaactaa tggtcaagct
     1921 atgattatgg gtatacaaac atataataca agtgttttag gtggtattgt agcaggatta
     1981 attgtttatg caatatatga taaagttagt aatttaaaga taccagaatc attaggattc
     2041 tacagtggac caagattagt tccaattgtt agtttaatag ttatgagtat agttggatta
     2101 ttaataccta ttgtttggcc accatttttc aatgcattcc aaagtttagg aagatggatt
     2161 tcttcagcag gaccattagg atatttttca tatgcagtgg cagaaagagt tacaattcca
     2221 tttggactaa atcatcttgt aacatctgta ttccgtttta caccaatagg tggaactgct
     2281 gttattgatg gagaaacgta ctttggtaca ttgaacatgt ttatggcata tgtagaaaat
     2341 aatcagatta tacctcttga tttagctggt aaaatggaac aaggtaaatt gatgattcaa
     2401 tatggattag ctggtgctgc attggctatc taccgtacag caaaaccaga aaatagaaag
     2461 gcacttaaag gacttttaat atcaggagtg ttgacagtta ttataggtgg tataagtgaa
     2521 ccaatagagt ttctattctt attcatatca ccagcattat ttgctttcca tacatttatg
     2581 aatggtatag caaacatggt acttccatac ttaggcgtgt tgatgggatt cacaggagat
     2641 ttaattgcat ttataagttt tggtgtgtta agaggaacag ctacaggatg gccaatagca
     2701 gtattagtag cagttttata ttttgcaata tactattttg tatttaagtg ggcaattatt
     2761 aagtttaata taaagacccc aggacgtgag gataaagaaa taaaagtatc tgaaggaaat
     2821 ggttcagatt tcaaaaattt gtctacatat aaaggacaac aaatgatatc tgctttaggt
     2881 ggtcaatcta atatattatc actagataat tgtgtaacta gattgcgttt aaaactacaa
     2941 gatgtatcat taataaatga ggatgcaatt aaagaggctg gtggtatagc agttgttaaa
     3001 ttagatgagc atacaataca agtaattata ggaactcaag tgtattcttt aagaaagcag
     3061 atggataaag ctatggaagg tcatttggag gcatgtaatg attaattttg ataaaaaagt
     3121 agaccgattg ggtacatatt gtacccagtg ggactatgta gaagatagat ttggtaagaa
     3181 ggatttgctt ccttttacaa tttcagatat ggatttagag tttccatttg aaataacaga
     3241 ggtgttgcag gaaaggttaa atcatagagt tttgggatac agtagatgga aacatgatga
     3301 ttttagaaat tcagttacga attggtatat taaaagattt aattgtagcg ttgatagtaa
     3361 ctggatatat tatagtccaa gtgtaatgta ttcaattagc aaacttattg agatgttaag
     3421 taatgaagga gatggaatcc ttataaatac tcctgcatac aatgcttttt atgatgtgat
     3481 aataaataac aatcgtaata ttataaagtc acatcttgta aataggaatg gattctattc
     3541 aattgatttt aatgattttg agaaaaagtg taaaaaatct aagatattta ttttatgtaa
     3601 tcctcacaat ccaactggta gagtatggag tgagttagaa cttgttaaga tgataggaat
     3661 ttgtaagaat aatgatgtca agataatatc agatgatata cacatggata ttgtatatga
     3721 caatagaatg acacctatct taaatgttgc aaaggactat ttagattctg tattcatttg
     3781 tacatcagcg tctaaatctt tcaatatacc agcattgact gggtcatatg tgattatacc
     3841 aaatgaaggt attagaaata aatttgaaaa tatcactaga taccgtgatt ttgtaaattc
     3901 gccagcaatt ctagcaatat tagctacaat ggtctgttat gatgactgcg aatattggtt
     3961 agatgaacta ttaaaatacc ttaaagagaa tcttaaatat acgattgatt atataaaaga
     4021 taatttagaa ccattgaaat tggtcatgcc agaaggctgt tactttgctt ggatagattt
     4081 ttccgaactt aaaataagtg gtgagaaatt ccaaaaatta ttgatggata ttggagaagt
     4141 tgctattatg tcggggtctg tatatggtga agaaggtgag ttttatttaa ggttaaatgt
     4201 ggcatgttca agagaaaaac ttgaagatgg tttaaatagg attaaaaaaa ctatggatta
     4261 tattgcaaaa agaattttat agtaggaagg gagatagtta tgggatattt aaaaacaatg
     4321 gttgatgtta tgactactga aatgaatgcc ataagatgtt taatagatga agcaggaata
     4381 gaatatgaaa gtatagttag tgaaattgca aattgtgaag gcaaagtaat ttttatgggt
     4441 gtaggaaaat ctgcacatat aggtaagaaa ttggcagcta catttgctag tactggtaca
     4501 cctagctttt ttgtacatgc aacagaggca gtgcatggag atttaggaat gattgaaagt
     4561 aaggatatta caattttaat atcaaatagt ggaaattcta tggaagtggt aaactgtata
     4621 aaatatatta aagcaatagg ttctaagaca attgcattta cttcaaacag aaattcagta
     4681 ctggcaaaag agtgtgatta tgctttaata tatcctgcaa aggatgaagc agaccattta
     4741 aatctagcac caacaacatc atctacaatt actttggttt taggagattc tattgcatgt
     4801 gcattatcta agagtagtaa ttttggttct tcagattttt ataagtacca tccaggagga
     4861 agtttaggtg agaagttaaa aacagctaac aatggataaa agcaaaaagg agagtagttt
     4921 ttatgttcaa aatgtttaaa aaaaaatcaa taaaatcacc catatcagga aaagtaatag
     4981 agttatctaa aatacaagat ggtgtatttt ctcaaaaaat tatgggagag ggtgtagcta
     5041 tagattctac aggagacatt gtatatgctc caatcaatgg aaagatagta gtagtagcag
     5101 agactaaaca tgcatttgta atagaattag aaaatgggat ggaacttctt attcatgttg
     5161 gtttagatac tgtaaattta aaaggcgaag gttttgaggt attggtgagt atgggagaac
     5221 aagtgaagga aggaacacca atgttgaaaa ttaaccgtcc tttgattgaa tcaaagggta
     5281 tatcacttat tactccagtt acaataacta atcattcaga gtacaatatg aatacatgta
     5341 atgtaggcaa tagtgttgaa ggtgggaaag atactgtaat tgagtttaaa taaagaacta
     5401 aaatacaagg ttaatattta taaataccta taaacttatg ttttataaga ttgattgtat
     5461 agatttgttg tatagatttg ttgtataaaa aagaactctt taattataaa ttaaggagtt
     5521 cttttttatt ttgtaaatat tgtttagatt tatatagaaa aacacttagt aataaataga
     5581 ataaataagt atttatatag ctaaaaatct aaatagtttt gtttaaatat atttttatat
     5641 tttgtaattt caaattaata aataattaga tttaataaac aaaaaataaa aatgttgatt
     5701 atattaataa actttaatat aatatattta tgaaaaatgt aaactgtgaa atggaggtag
     5761 taacatgaaa attgaaaatc tttctattga tgatattaaa cgaggctata tatttaatga
     5821 tgatttaaat tgttatagtt gcattaaatg tacaaaaaca tatgaggtag gagaaatata
     5881 taaaataggt aatagattct ttgaagcttc aaaagctatt gaacttcata tggaattaga
     5941 acatagtgat tatttagagc aattgcttaa tagtgattca aaatacaaca cattgactga
     6001 aaatcaaaaa caattatttc aattatttat tagtgattta ccagataagg agatagcaaa
     6061 acaggttgga gtatccacat ctactatacg ccatcaaaaa tttattttca gagaaaaagc
     6121 aaaacaggct aagctctatt tagcactata tgaatctgta tttgaagata aatctaataa
     6181 aagtagtact ataataccaa tccatgaaca tgctcgaatg gtagatgaaa gatatgtagt
     6241 aactgaagaa gagagaaaac acattttgga tacatcattt gaaagtatga atcctttaaa
     6301 attaaaagta ttttcttcaa aagaaaagaa aaaggtcgta attttatcta agattttgga
     6361 acaatttgaa cgtgggaaga aatattcaga aaaggaagtt aatcagattt tagaatctat
     6421 atatgatgat tttgcaacaa ttagaagata tctaattgag tatggtttta tgagtagaaa
     6481 taaagaatgt acaaaatatt ggttaacata attaaaataa taaattttac taatgtgtaa
     6541 tgttattttt atctaggggg aggagtcaaa tatgaatgat gaattaaaat ctattttata
     6601 caataaaggt gtagacattg ttcgctttgt tgatatatct gaatttccaa taaatcaaac
     6661 acaaggtttt tctaaagcaa ttttattttg tatagggtta tcaaaaaaat ttattacaga
     6721 tatatacaat aacttaccta cagatagtga tgagtttttg gaaaaagagg agaaagtaga
     6781 agaattagct gactggattt caaaatatat tcaaaataaa ggatatagag catattctca
     6841 atcggagaaa aacaatctag aacatggata ttttgaaaaa gcctatatta atccagaaat
     6901 gcaatcaggg attagtcctt taccacataa gacaatagca aatattagtg gcattggatt
     6961 tatgggaaaa aataatttgt ttgtaacaga ggaatatgga tgtgctttta gcatgtgtac
     7021 agtacttaca gatgctccaa tttctgttga aagatatcct ttgattgatt caaaatgtat
     7081 ggattgcaat gtttgtgtag agaactgtcc tgcaaaagct atacatggaa atgaatggac
     7141 tttacctgga aaaagagaat ctattattga tgtttcaaag tgtttttgtg tattgaggtg
     7201 tatgatgagt tgcccatggt cattaagata tgcaaatcaa aaataacttt actagagaag
     7261 gtattaaatt gaatattata aaatttttaa aatgtaagat tatataagat ttctcaaaat
     7321 aaaaatttgt atagaacact cagaaatgag tgttttttta ttgggattaa attatattga
     7381 tacaaagctt aactatttta atcattatat aaaatttgta ttaaaaaatt aagaataact
     7441 tggtaatagt gaaaatataa tgagattata attgatttat aatataacta taatgatatt
     7501 gtaaaaatga aaattgtcct ctcaaaattc ccaaagagag taaaagtcac ttcagttata
     7561 gtcaaaaaaa tttttctgtg aaaagaattt agatttgaaa aggaggaatt aatcatggaa
     7621 attgaaacta aaactccaga ttggattaat gtactagaat taaacagtaa aatagatatt
     7681 actgggaaat atgatgtaag taatatgata caaaatattg tctctgataa gtcactagaa
     7741 ggttccatta tatattttcc aaaaggtaat tacttatttg agaaaggtat taaaattagt
     7801 caacaaataa cacttcaagg agattcttat tatggaggag gtaatcaagt atcaaattta
     7861 gataaaaaac aatcaatcat aggaacaacc aattttataa cccgaggagt ttctaatatg
     7921 agtattatta cattgtcagg aacaagtcaa tgtatcaaaa atattaattt ttattatgat
     7981 agtcatgata tagagaaaat accgcctaaa aatgtatctg ctattacaga atatggagaa
     8041 acacaaggac tatctcattt tgaacatctg tttatttctg gattttcagg gataggaatt
     8101 gaaattccat actattcaac tggtaatgat attactgtta gttcatgtgg tcttggtatg
     8161 aggcttggag agaagtcaat gctttctagt agcaagattt acgaatgtaa aaatggaatg
     8221 gagattacta ctggtgttag cttaaataat gtgagaatag aagaaataaa agaaataggt
     8281 attaataata aaggatttgg ttttaacctg attatgaatc ttatggtcga ccaatgtgga
     8341 tattgtggat ttatgtttga aaaaatgtgc tatagccaga taactgccag aattactaga
     8401 tgcggtcagt attataaaag tgttgattat aatgcttatg agaatatgga agataggaaa
     8461 gaagaagctt attccatttt ttatggagat attttagaaa attgcaatat tgtattgatg
     8521 aatagtaata ttgatacctt ggaaaatgat tcacttgatg aacataagat atatgtaatc
     8581 aaggcaaatg aaacaaacaa tgtaatgcta acatgttatg ctgaagcaga taactttata
     8641 caatgtgcaa agggcaactt gctgttagaa aatggtgaaa atacttataa attttataat
     8701 ggtgagattt gttctgtagg aggtgttcaa atttctgata tagatgaaaa agatttaatc
     8761 aaaataatag agaacacttt gtatatagat gataaaggta agtatttaat ggttcctaga
     8821 ttaaaaaaga atactgtaat atattcagta ctagattcta cagaagaaat aaataaatta
     8881 catggtggaa tatgggaaca gattgatgta aaagtattag ctggggaatc catgtactat
     8941 tataaaaaga taaaagatta aattatcaaa ctaggaggta gtgattaatg gaagagtcta
     9001 taataattaa agatataagt ggctggatta atgtccttga ttatggaatt tgtaatgatg
     9061 aaacaaaaga tgtaagtttt aagttgcaag agattatgga tgctgtacca gaagattcta
     9121 ttatatattt tccaaaagga aaatacttat ttgaaagtgg tgttaagatt aagaaacgat
     9181 taactttatg tggagattct tatattttgg cgaatgttcc taaaaatact gctggagtaa
     9241 cacaatttac ttttaaagga aagaaaaatc ctaaaagtga aaatatagca attataacag
     9301 caaaaagtgt aagacactgt attaagagca tttgctttta ttcagatagt tgtgatagag
     9361 atatgacatc taatcatgaa cctccaacag atggaaaacc tagatttcat cataatgtaa
     9421 ttataaatta tagaaatata tcggctattg tatgtgaaga taaacaggga gaatcaggtc
     9481 attataaaaa tctatctttt agtggttttt ctggaattgc acttgatatg cctaataatt
     9541 ctacagcaaa tgatattaca atttttacat ccggacttgg aattagtaca ggagaaaatt
     9601 caactattgc taacagtaag gtttggggct gtgttgatgg aatgataatt tctactggaa
     9661 cttttataaa tggtatgagg gtagaagaaa taaaaaaagt tggaattaaa aatattggta
     9721 gaggtttaaa ttttattaca aatatcacaa ttgaccaatg tggatattgt ggagtttggt
     9781 ttgattctat atccaatgtt cagatatcag gaaatatcac aaggtgtggg cagtactatt
     9841 atgatgtaag ctatgataat tatttaatgt tggataatag agttaaagaa gcatattctt
     9901 tattctatgg taatttattg gaatcaagta atatagtttt atcaaatacc aataaagata
     9961 attgggaaga tttcaaagaa gataagcata aggtgtatct tgtagaagca cttgaaacca
    10021 agaatgtact attaacatgc aatatagatg ctactgactg gattgttaag tcagaaaaag
    10081 gaaatttaac gtacaataat atgcgacaaa ctgttatatt ttacgatgga aaactaagta
    10141 gtatcaatgg aattggtata tctgatgaag attatgggga taaagtcaag ataaaaaaag
    10201 gaaatatata tataaatagt aaggataagg atattaagat gcataaacca gaggtaggtg
    10261 acattatgtc aacaattatt aaagataaaa gtattctttc tgctcattat gggggaacat
    10321 gggagaaaat tggtgaaaaa atagagtttg gaataactgt acactattat aaattgatag
    10381 agaaataagt aaatacgtag tatttgaata gatgtatttt attggagagc taggactata
    10441 gttttaatgt aaatggtttg gtaatagcat ggattgaata atataaaaat aatataaaaa
    10501 attaatttga ttatgtaaaa ttctatgaag tagtaaaact gtgactttag tcataggagg
    10561 ttcaaactaa gtaaaaggga aaggaatata taatattatg gaaggaagaa ctgggattaa
    10621 agatggaaga tggattaatg tagtagaaag aggtattaaa aatgatggtt cgtacaacgt
    10681 aggtcctgct ttgcaggata ttattgatga aatagaaaca gatttttgtg tcttatattt
    10741 tccaaaaggt aaatacctat ttacaagtgg tgttaaaatt aataaagaaa ttgtattgca
    10801 aggtgattct aattcatcta caggcactac acaatttata actcgtggag tagaaaatat
    10861 gagtattatt acattgacag ggaaaaaaca atgtattaaa aatataaatt tttattctga
    10921 tagttgtgag atacaggtaa ataaagaacc accgacaaaa ggtaatccta aatatcatta
    10981 tgagatgatt attaataaga atgaaaagaa tgttgagatg aataatgtat cagcaatcct
    11041 gtatgataac agtaagaata tgattaaagg tctaggtcat tatgaaaata tttatataag
    11101 tggtttttcg ggtacaggaa ttaggatacc atattactca attgtaaatg atattacagt
    11161 ttcatcttgt gggctgggta ttgatacagg aatagacaca attatttcta atagtagaat
    11221 atctaagtgt caaaatggaa tgaggattag aactggaact agtataaata atgtaaggat
    11281 tgaaaaaata cagaaagttg gtcttataag tagtcaagtt aaggggtatg aggggtatgg
    11341 aagttataaa attaataata ttacgattga ccaatgtggg tattgtggct tttcatttga
    11401 ttcaatgaaa gatagttatt tttctggtat tataagaagg tgtggtcagt attattataa
    11461 tacagattat gacacatatt taagtattaa agatagagta gaagaagcat attctttatt
    11521 ttatggaaat tattttacag aatgtaatat tgatttagtt agtgataata aggataactg
    11581 ggatgatggc ttagaatata aacataaagt ttatgtattt aaaacccttc aaataccaaa
    11641 attaacattg agatgcaata tagatgccta tgattatatc gttaaatcgg tacatggagg
    11701 aggtaattta atgttaaaaa ataattttaa caattatata tttattgatt catctaatcc
    11761 agaagttatt aatggaatta attttaatta tcaaaagaat ggaaacttgt taaggttaaa
    11821 taatggtaaa ttaagttata aaaatggaaa ggaagaaaca gctatattca gacctaatta
    11881 tggtcttatt gtagcatcaa cagattcaga atgtgaacaa atagagacta gctatggagg
    11941 aaaatgggag aagcttggtt ctgaagtaat tggagaagaa acggtatatt attataaaca
    12001 tcatgaacca gataaaacaa accaaataca ataaaatttg tattatataa tgatataaag
    12061 ttttaatata tagtgtttac ctttaatgta atattggtat atttgtatag tattaaattt
    12121 gttaaaaagt aaaattgtag ggtgcttgaa aatagcacct tttttagttt cattataaaa
    12181 ttagttttga aagtttagga ataatgtata tttattttta aagaattata accttattaa
    12241 ggatatttta aatgctagaa atgaatcagt aaatcatact ggaattatct taaatgtttt
    12301 gattaaatta agtatttaga gctataatta tattaaaaat atattagaac ataattatat
    12361 tactatggag gttaaatatg atagtaagtg tgagtagaag aactgatata cctgctttct
    12421 atagtaagtg gttttttaac agacttaaag aaggttttgt ttatgtaatt aatccaatga
    12481 atccaaaaca ggttagtaag atagagttaa atccacatac tgttgattgt tttgtatttt
    12541 ggacaaagga tgtaactcca atgttatatg atttaaataa attaaaagac tataaatatt
    12601 attttcacta tactataaca tcatatggaa aagaagtaga gacatgtatt ttagataaaa
    12661 gaaaggtaat agattcattt aaggaattgt ctagaaaaat aggcaaagaa agagtaattt
    12721 taagatacga cccgattttc ttaagtgaaa agtacacagt agattatcat atcaaagcat
    12781 ttgcgagttt atgtaatcag cttgatggat ttacagaaaa atgtataata agttttatcg
    12841 atttatataa gaaaacaaaa tttaatacta aagcattaca tataaagcca atagaaatta
    12901 cagaaataga aacattatca aaagagattt ctaagattgc tcataagcat gggataacac
    12961 ttgaaatgtg ttctgaagaa tataatttaa gtaaatttgg gattggaaaa agtaagtgta
    13021 ttgatgatag attaatatca aaaattatag gatgtgaagt agaggtaaaa aaagatagta
    13081 cacaaagaga tatttgtgga tgtgttaaaa gtgtcgatat aggacaatac aatacttgca
    13141 gacattattg tctgtattgt tatgctaact ttaattatgc aaaagtagaa gaaaactgta
    13201 ggctttataa agaagataat aaattactca tagatacttt aagagatgat gcaaaaataa
    13261 gcattagaga tatgaagact attaaagtag ataagaataa acaaattagt atatttgatt
    13321 aaaataaata tactaattac cttaatatat taagaatata gatacttttg ataacaaaat
    13381 taaacttaat agatattttc tatataagaa agatggtcat aatatgtcaa tttgaccatc
    13441 tttttgatat aattaaaaca caaataattt agtaacaaag gaggcagaac ttgaatttat
    13501 taaaaaaata tcctatacct attgcaagtt tgattttgtc aatctttact ttaggtaact
    13561 tattacaatc ttatagtgaa tcattacgta atgtaattgg atttatagga tttattttgt
    13621 atgcaattta tatagtcaaa ataatattac ttagaaaggg tgttaaagag caattagaga
    13681 acactttaat atcaagtaca tttccaacta taacaatggc aacaatgata tttgctacat
    13741 atataaaacc attatcttta gaattaagta ttatgatttg gagcatagga attgtgggtc
    13801 atcttgtgtt aatagtctta tttagtaaga agttcttagt taaattctca ataaaaacgg
    13861 tatttccatc ttggtatata gtatatgttg ggatagttgt agctagtgtt acggcaccag
    13921 catttaatca acttttgatt ggcaaaattg ctttttggat aggatttgta tcttatatag
    13981 ttcttatacc agtaatttta aagagagtat ggataatcaa ggaaatgcct gaaccatctt
    14041 taccaagtat agctatatta gctgcaccag ggtcactatt attgtctgga tatattaatt
    14101 ctttttcaga taaaaataat gtagtattat acttgttatt catattatca attgtatttt
    14161 atattatagt tttgggatat ttaccgaaat tattaagatt gcctttttat ccgagttttg
    14221 ctgcatttac atttcctatg gcaataagtg caatgggtat gaaactaatg aatggttatt
    14281 taactaaatc aggtcatttt ataagttgga tttcatatgc ttctaagtta gaagagataa
    14341 ttgctacagt gattatttta tatgttttag ttttgtttat tatatatctt agtaaatctg
    14401 aaactacatc taaagctaaa taagaattat taaatatgtg tatttaatag gaatattgat
    14461 ataaatatat gaagataaga taaaccatag aaacttaatt tagcttaatt ttattggagg
    14521 aaaacaaatg aaaacaaaag aagaatattt aaaagaagtt agaaacatat cagaagaata
    14581 ctttagaaaa ggagagtttt tttgctctga agcagttctc cagacaataa atgatgcttt
    14641 aggccaacct ttaagtccag agataactaa gttagcatca ggatttccga taggacttgg
    14701 aaaggcacaa tgtctttgtg gagcaatatc tgggggagag atggctttag gtatagtata
    14761 tggaagagtt catggtgaag ctatgaatcc aaagatgttt gagcatgcta aaggtttgca
    14821 tgattatatt aaaaaagagt atggtgcaac atgttgtaga gctattacaa agaaatggga
    14881 tggtgataac tttatgtctc ccgaaagaaa agagcactgt attaaaataa caggtcaagt
    14941 tacagagtgg gttgcagata agcttataga agatgaaaaa cttaatatca aatagtgtaa
    15001 tattagttgg tgaatttata aagttaaatt tacttatagt ataagatact tgatattctc
    15061 gtattgatag aaaaatttat agcatatgta tttaatgaaa tatacttata tttagagtgt
    15121 ggtttaattt cataaataca tatgctatta ttttaagtat ataagcaaat ttatttaaat
    15181 aaatagaaac agttaattta tatgtacaaa actatatatg attagtgtaa ataaatacct
    15241 attttataat actcaacata aagacaccag acatgattag tattatacca ataaaaatag
    15301 caagccattc ttttttgttc ttcttttctt taaaaaatat aatccctcct aaagtggcta
    15361 ctatcacaca actctgagag atagaaaaac ttattgtaac tcccaatgta ttagtcgtta
    15421 tgaacatacc taaatttgct attgaccaca atataccagt aattaaattg aataaaacat
    15481 tttccctata tacaatctct ttagaaaaat acttgacaat aatagatgaa gttatcaaca
    15541 taccaacaga ttgaggtaat ataattctat atccttcaat taaaaatatt tgattagtta
    15601 caacatataa tgataaaaat agagatgata ataatacaac tccaacacat tttaacatat
    15661 ttttatctgt agatttttta gtttgataat ttgtgagaag tataccaagt attatacata
    15721 atattgataa agaaccaatc agtaacattt tagaactggt ccattcatta aacaagatta
    15781 cagctaataa tgtcgtaaaa gttaattgtg aaccatttga aattggcatt actttagata
    15841 cactagcaat ttgaattgct ttaaactgca ttaattgtcc caaactccag aatatgccag
    15901 aaatcatact tatacaaaat gaaaaaaatg taatttcagg atgtataacc agagttatta
    15961 tagtggaaaa tataaacgca cttatggatg tacctaaaag ctgttcatga ggagaacttt
    16021 tctttagatt tgcaactatg ggcatcaatc cccatcccat tacaggaagt aaagcaataa
    16081 ttattgtcag cattaaacta tttcctttca tattaaattt agacagcttt taatttatca
    16141 tctaaaatta aagtgttcaa tacataaaaa ttaccgtatt taatcaggaa atattagtag
    16201 ttttttagaa aaacattttc cattaaaata aagacaaagg gaaggagtaa aattgaaaat
    16261 gttaactgat atgattcaaa atcgtgaaat taaaataata aagtttttat taaaagaagg
    16321 tcatacaact gtaaaagcaa tagcagatga tttagatgtt tcagaaaaaa cagtttcaaa
    16381 atctcttaaa gaagtagaag cagtgcttaa aaagataggt ctttctttaa taagaaaacc
    16441 taagataggt gtttatattg atggagattt aaaaaaaata cttccttacc tagataataa
    16501 aggaagtcaa attcctacaa ccagagagga gagagttatc tatatatatt cagtactttt
    16561 aaagagtaat gattatatta ctatacaaca actttctgat gaactatata taagtcgtgg
    16621 aactattgaa agggatttag cagaagttga aaaactgcta aaaaacgaag ggatttccat
    16681 atataagaaa cctagtaagg gaataaagtt aaatataagt gaaagagata aaagacaact
    16741 tactgctaag tttatacata aattttggag tagaaactgg tatattaagc aagagcaaga
    16801 aagcttttat caagcatttg aaaagataca agcagatgta aatggtattt tttcggaaga
    16861 tgatttatca ataattattg atattcttag gaatttcagc agagaaagaa aatttgagtt
    16921 ctctgattat gaatttcagt cattagttat tcatttggca atagctgtag agagaattag
    16981 aaaaggcgaa tatatagaag aaagtttgta tactggtaat atagaaaata atcaaatgtc
    17041 aaataccaat tatttagcaa aacaattaga agaaaaattt tcaatattat taccaaaatc
    17101 tgaaattgga tatataaatt tacatttagt agcgtctgac caacatagag atactaatga
    17161 actaaaaaat acttcaacta atccttgtga gacaagtaca aataatatat caaatcttcg
    17221 ggaaattata aaaaatacat tgtatgagac agcttatgac aaggatttaa ttgatggatt
    17281 gacttcacat gtacattcat caataaatag actgaaatat ggacttagta ttaaaaatcc
    17341 atatgtaaat acaatcaaac aaaacttttc tttatcattt gagcaagctt tagatttaaa
    17401 gaaagtaatt gaatttatat atgatattag gataaatgat gatgaatgtg cttatatagc
    17461 attacatttt gaagctttta gagaaagaat gaaagaactt ccacaaaata ttagagtaat
    17521 tctagtatgc agtacaggat taggttcatc taggttattg tctgcaagaa taaaaaaata
    17581 ctttccaatg ataaagattg aaaaagtact ttccgtacaa gaattagtat ccagtaaaat
    17641 tgatgcagat ttagtaataa gtactattta tttagagtta gaaacaattc caaccatagt
    17701 agttagtcct attttaaatg aaagtgatat aagaaccttg gaaagaaata tacaaaatgt
    17761 ttcaagttgt acttctaaga agtataaatc tttcagaaac ttaatctttg aagaaaatat
    17821 attgttgaat attgaagctt caaactatga agatgcaatt aagtatataa cagataacct
    17881 aataaaaaaa ggttttgcaa aagaaggtat agctaaaagt gcaattgaga gagaaaattt
    17941 atcttacact tctttccaat caatagctac acctcatgct aatcctagtt atattaaaaa
    18001 atctaatata tctgttgcaa cgttaaaaaa tcctattaca tggggaaatg aaaaggtgga
    18061 agttattttc tttatttcat tagaaaatga caaaaaccta gagcttgatg aaatatatga
    18121 agttttttat gactttattg acaataaaaa aaatataaat gacatattaa gtgcaacttc
    18181 cacaaaggaa gtgtacgatt tgctagtgga ggagagtata tagtgaaaat atcagatgta
    18241 ttgaaaaaag agcaaattgt ttttaatctt gatacaaata caaaggaaga aacaataaaa
    18301 aaattaagta gtatatttgt tgaaaatggg attgtggaca atgaagaaga atatgttaag
    18361 tctgttttgg aaagagaaga acattcaact acaggtattg gtaatggtat tgctattcct
    18421 catgggaaaa gtaatgctgt caaaaaatct tctataatat ttgcaaagac taagcataag
    18481 attgaatggg atgctttaga tgaaaaacca gtagatagta ttttcttatt ggctataagc
    18541 aatattgata aggatagcaa tcatcttgta ctattatcta aattagcaac taaacttatg
    18601 gatgatgaca atgtagatgc actaaaatta gccaattcag aacaagaaat aatcaatata
    18661 tttagtgaag aaggagagat gtagaaatga aaagaaaaat tatagcagtt acagcatgtg
    18721 caacaggagt tgcacataca tatatggcag ctcaagcatt aaagaaagct tcaaaaaaga
    18781 tgggtcacct tataaaagtt gaaacacaag gagctacagg aatcgataat gagttaacta
    18841 caaaggatgc acaaattgca gaagtagtaa tatttgcagt agatactaaa gtcagaaatg
    18901 ctgaacgttt tgagggaaaa gaaatactag aagtaccagt taatgcacct ataaaggatg
    18961 cagagaaagt aataaatgat gcattaaagt taattgacac taaataaatg gagggaaatg
    19021 taatgttgaa aaagatagtc tctgagttaa aaaagcatgt cttaactgga atctcatata
    19081 tgattccatt agtaattgca ggtgctatga taatggcgat atctcgtgta ggtggttctt
    19141 tctataatat accagatata tgggatgcta aatatgcaga aagtgctagt agtattgtta
    19201 gattattaca tgatttagat gggtttggag gtactgcatt aggattaatg tttcctgtaa
    19261 ttgctgcatt tataggattt tctatagctg ataaattagc tattgtacca ggtcttgttg
    19321 gaggtatgat tgctaaagat ataggtgcag gatttttagg agctttggca gttggtctta
    19381 tagcaggata tacatgtttg tttattaaaa atcatgttaa attaccaaaa tcagcagctt
    19441 caatagtacc aatatttata gtaccagtat ttgggacatt aatcactgtt gtattaatca
    19501 attatgtgat aggtatacct tttgccacat taaatactgg attagaaaat tggttaaatg
    19561 gattatctgg tacaaatcag atactaatgg cagctattat aggggctatg atggcagttg
    19621 acttaggtgg accagttaat aaagcagctt taacaacatc acttgcatta ttaacaagtg
    19681 gaatttatgc gcctaacact gctgcaatgg taggaatagt tataccacca ctaggattgg
    19741 gacttgctac tatactagca aaacaaaaat ataataaaca gttacgtgaa gctggaaaat
    19801 catctcttat aatgggttta attggagtaa gtgaaggagc aattcctttt gcggtagaat
    19861 ctccattaaa agtaatacct tcatgtgtaa ttggaacagc aattgcttca gctatggcag
    19921 ttggtttagg ttcagtaaat gcaactccaa ttagtggatt ttatggatgg tttacagtag
    19981 agaattggcc aatgtatgtg ttatcaatag cagttggaac agtaattgta gctggattag
    20041 ttatagtatt gcgtggaaat ccagtgattg aggatgatga atttgaagat gatgattttg
    20101 atgaagcaga gtgggaatct taaaatttaa taactattta agacgtgtta taagctatat
    20161 tcaatatgaa tcttatacta aataaagtgt taaatattca gtttagactt aaatataaaa
    20221 gataaagaac agaggagaat aaatgataaa agcacatatt gttaatcata cacactggga
    20281 tagagaatgg tattttactt ctggagatgc attagtactt agtgaacaac tatttacaga
    20341 tgtaattgat gaattagaac gtaatccaga tgtaagtttt gtacttgatg gacaactttc
    20401 tattttggat gattatgtac aattacacaa agaaaaaata gaaatcatta aaaagttaat
    20461 aaaagaagat agactacata ttggaccatg gtttactcaa actgatgcat tctttgctag
    20521 aggagagtct attttaagaa acttaatgat tggaattttt gaaagtaaaa agtatggtaa
    20581 gtatatgaaa attgggtatt tgccagatac atttggattt aatgcacaga tgcctatact
    20641 attaaagcat gtaggtcttg ataatatatt cttttggaga ggtatacatc ttggtaaaca
    20701 ggttcaatca ccatatttta agtggaaaag cttaaatgga gaaagttata tatatgcagt
    20761 aaatatgcca catggatatg gaactggtat gcttttagag ccttcattaa agtatgttaa
    20821 tggacgctta gacccagcta ttgattttat taaatcatat actgatgtag atgaggtgtt
    20881 aataccttct gggaatgacc agttaaatat aataggtgat ttcaaaaata aaattaaagc
    20941 gattaatgat atcggaaagt attcatatat aacgagttca tatcaagagt ttttaaaata
    21001 tataaagtcc atagaatcac tagaaagcta tagaggtgaa tttagagaac ctgtattagc
    21061 aagaatacat aaatcaattg gttctagtag aatggatata aaattagcat gtgataaact
    21121 agaaaacaag ctgattaaaa gaatagagcc attattagta attgctaaaa agagcaaaat
    21181 tgaaataagc aatcagttac ttataaatac atggaaaaaa cttttggaag gacaagcaca
    21241 cgatagttta gctggatgtg taactgatac tgtaacagat gatattcttc accgtataag
    21301 agaagcaaat gaaatatgtg acagtattga aaatactatt gtaaaaaaga tttcagaagg
    21361 gcttaaatta tctaaaaatg atattttagt atttaataca gaagctaagc gttttaatgg
    21421 atataaagag atacaagttg taagtgatag taaaaatatt tattttaaag ataatttaga
    21481 tgctactata attgaagaaa cttatgtaaa accgagagaa aatgtattag aagaaacacc
    21541 tgctggtaat atatttattg aagaaccagg atattatata ttaaaagtaa gaataaatgt
    21601 acagcttcct gcacttggtt ataaagttgt tagttttgaa ttaagtgata aagaaatggt
    21661 gtcacttgat aaatctaatg acacttttat atctaatgat aattataaga taatatatga
    21721 agatggaagc ttaaatttac aacttaaaga tggaacttac atatcaaact ttttaacatt
    21781 aaaagatagt ggtaatgcag gtgataccta tgacttttct ccactaaaaa atgatgagaa
    21841 tataaaactt tcgtttgata aagtgtatac agaaaaagct ttaggatatg aaaaaatggt
    21901 ggttaaaggt actactttac taccacttac attagaagat agaaaaaaca aatatcttaa
    21961 tggtaaatta aatgtaaaag taagtattgt cttatctaaa gaaaacccat tgatggatgt
    22021 aaaactttgt gttgataaca cgatatataa tcatagacta cgtgttcata taaaaactga
    22081 tataaaagat aataaaaaca tagcatcatt gccatttgga tatataacaa gaaaaaatgg
    22141 agttttagac aactgggaag atatttacag tgaaatgcct atagatttag aacctttgga
    22201 aagtaatatt acgcttacaa accaaaatag aagttgtact gtatttacta gaggaataaa
    22261 agagtatcaa catattgaag atgaaattgc attgacctta cttgctacta cagatgaact
    22321 aggaaagcct gatttattat atagaccagg acgtgcttct ggtgatacaa ctaaaaaagg
    22381 tcatataaga attaaaacag ataaagctca aatgcttaag gaattagaat tttcatttgc
    22441 aatatatatg gattctaaat catttgatga attggaaatt gcgaatttaa cccacaatta
    22501 tctaagggaa tgtgtaaatt atcaattaca ggattacaat ttctttttat atcatataga
    22561 taataagatt caaaaatcaa ttgtcaataa aactgtaagt agagaattag aaataatatc
    22621 tttaccagaa aactatctta tatcagcatg ttatccttct tattacagta aagataaatt
    22681 tataataaga gtggaaaatc caagtagtaa tagaatgata ttggatgagc aaatatttaa
    22741 aaatagaaat gggaaaattg taaatgcaat agaagatgta gaagaggaac aggtatatga
    22801 aatagcacct tttgacgtta tttcaatatt attggattta taagtgtaaa agtaagttta
    22861 ttgtttaaag tctgacagat attaatctgc cagacttttt aatttgtata aatttgggta
    22921 aatattaatg aatggtttta gtatttaagt atgaatttag tatttaatat agaatttatt
    22981 gaagtagaat aattagttta acaggataag cagtttaaat aaagaattat tatattagag
    23041 tgattttata tataatttaa aataataaaa ttttaataaa atgagttaaa gattgtatat
    23101 taatagagtt gatgtagtta caaaaaagtt accaattgtt atgtatttac aaaactgata
    23161 tattaattac ataaaatcta aaatagtttg taataggagt atatataata aaaattttaa
    23221 ttaaataaag ctaggtatat ttataatatt aataaatata ttgctataaa agtttgttta
    23281 ataaattaaa taaagaaaag aggagaataa aatgtacaac atagatgata tgatatataa
    23341 ttgtccagta gaagctttat caaatatttt aggtaaaaaa tgggtggcta taattatatg
    23401 gaaaatacaa gaagataaaa aacgatttgg agagctacaa agagctatac cagactgtag
    23461 taagaaaatg ttagttcaac aactagattt tttaattgaa caggggatta tagtcaacca
    23521 aaaaaagttg gttaataatg ttgtagagtc aacatatttt ttaagtgaat caggattacg
    23581 attgcttcct gtcatggaaa aaatgattat gtggagcaat aaaaatttaa attgtgataa
    23641 atactaaaat ttactctgta agtaatgaaa atttaattaa gctatgagta gaaaaatgta
    23701 ttaaaattac ataatttttt agttagattt taatttagaa atgggattgt aatattggaa
    23761 ataaaataag gaggaatttt aatttgcaaa atgtaaattt atttttagta tttatagaag
    23821 gtatagtatc attcttttca ccatgtatac tgccaatttt gcctatttat ttgagtatat
    23881 tgtcaaatag tagtgtagaa aatttaaaag aaggaaagac gagttttata ggaagttctt
    23941 tatttaaaaa tactatattt tttgctcttg gaatctcaac aacattcttt atattgggtt
    24001 catcagtaaa agtattgagt atgtttttta atgaaaataa agatttaata atgtttattg
    24061 gtgggattat aattattatc atgggattat tttacatggg aataattaaa tcttcaatat
    24121 tgaatagaga aaaaagattt aatgttaagt ttaaagaaat gaaagcaata acagctttta
    24181 tattaggttt tacgtttagt tttggatgga caccttgtat tggtccaata ttggcatctg
    24241 tattagtcat ggtttcaagt tcaagtaatc atcttagtgc caatctttta atagcagtat
    24301 atactattgg ttttattttg ccattcataa ttacagctat gttttacagt aaactattta
    24361 aaactataga taagataaaa tctaacatgg aaattattaa aaaaataggt gggattatac
    24421 ttatagtatc aggaatatta atgatggtaa atggatttgg aagtataagc aaacacttta
    24481 atacgtcaca aaatagtaaa attgaaagca agcaagaaga aaataagcga gaaaattcta
    24541 ctgataaaga agaaaattct gatggtaatg atagtcaaaa agactctaat aatgacaata
    24601 atgataaagg gtctaatgat gaagatagaa taaagtctat tgattttact ttaacagacc
    24661 agtatggtaa aacacataaa ttaagtgatt atgaaggcaa agttgtattc ttaaatttct
    24721 gggctacatg gtgtcctcca tgtaaagaag aaatgcctta tatagaacaa ctgtataaag
    24781 actataataa aaataatgat gatgtagtaa ttttaggagt agcttcacct aatttaggta
    24841 gagaaggttc aagggaacat gtagttaact tcttaaaaga acaaggttat acattccctg
    24901 ttgtacttga tgaagatgga gcattagcat atcaatatgg aattaatgct tttccaacta
    24961 catttataat tgacaaggaa ggatatgtaa ctcagtatat tccaggagct atggataagg
    25021 caactatggc atcatttatt gaaaatcaga gaaataaata aaagtattta agtataagtt
    25081 tataaatcaa tttaaggtta caaaaaagtg cctaattgta ccacctaaat aatcttgtta
    25141 tagtaaaagt ataaacaata caagaaaggg ttgaatttta tatgaaaaaa acatttgatg
    25201 ctataataat aggatttgga aaaggtggaa aaacattagc aggggatttg gcaaacaggg
    25261 gattaaaagt agctttaata gaaaagtcaa acaagatgta tggtggaaca tgtgtaaatg
    25321 tggcatgtat accaacaaaa agcttagaaa attcagcaaa cagcgtaaaa acaaagaata
    25381 taaattcttg ggatgaagta caagctgaat atgagaaagc tatagataaa aaagaaactt
    25441 taattacaaa actcagagaa gctaactata ataaattaaa ttcaaatgag aatgtaacta
    25501 tattcacagg aatgggaact ttcattgatg aaaaaacagt tcaagtcaaa actgaaaatg
    25561 aaatttatga gttagtagca gataatatat ttattaatac tggttcaaga ccatttatac
    25621 ctaatattaa gggaattgaa aataagaata tagtatatga tagtgagtct cttatgaatc
    25681 taagagtttt acctaaaaaa atgacaatta taggagctgg atttataggt ttagaatttg
    25741 ctggtattta tagttcattt ggagcagaag ttacaatatt aaactctaat aatggcattt
    25801 taccaaatga agatgttgag gattcagaag aaataataaa attacttgca aagagaaatg
    25861 taaaaattgt taataatgca aatataaaag agattaaaga agtttctgaa ttagcaatag
    25921 tagaatatga agtagatggt aaatctaaag aattaacaag taatatgata cttgtagcta
    25981 caggaagaaa agcaaacact gaagggctag ggctagaaaa tgcaggtata gaattaaatg
    26041 aaagaggatt tattaaagtc tcagaaactc ttaagactaa taaagagcat atatgggcta
    26101 taggagatat aaatggaggt ccacaattta cttatatttc attggatgat tatcgcatag
    26161 ttattaatca gttatttgga gataagacta gaacaactaa tgatagaaag aatatcccaa
    26221 attctatatt tataagtcca gcattttcaa gagttggtct taatgttaag caagctaaag
    26281 aaaagggata tgaagtatta gtggcaaaga tgccagtaga agcaattcca agagctaaac
    26341 agattggcaa ggcagatggg tttataaaaa tagtgataga taaaaaatcc aataagatac
    26401 ttggagctag tatgatatgt gaaaattcaa gtgagattat ccatcttatt caattagctg
    26461 tagatttaga agtagagtat acatatttaa gagaccgtgt ttatgcacat ccaactatga
    26521 cagaagctct taatgatatt ctatctccta atatgataaa agaagtataa cataagttta
    26581 atatataaat ctaaaattat cattataagt agattttaga aagaggctat ctcaaaaaat
    26641 agagataagt ctctttttta ctgtttaaat aataaaaata tattttaatg gtattaaaaa
    26701 ttatcttaaa aggtgaaata atctgtattt aatgtagtac agttatatct ttaaagcaag
    26761 gtggtgaaat gatataaata agatatctaa aagagggttt gatgatagtg ataaaagatg
    26821 gttttcaagt aaagaattaa caagacttat aaaggctaaa gaagaaatag aatggttatt
    26881 aaatagggat tacaaaatag acccagtcgt tacttttgtt ggtgatagat atcagttttc
    26941 tataagacaa agagatgcat taaaaagggc agtctgtact gatgaaaaaa atattataag
    27001 acaatcaaag aggctttctc tagataaaat caaagaagat accgtaaata tagatggctt
    27061 taatttgata atatccatag aggtaggatt atctggtggt actctagtaa taggaagtga
    27121 tggcaatata agagatttag caggtcttag gggaacctat aagattatag ataaaacaga
    27181 agaagctttg aatctgatag gtaaattttt taataaatac aatgcacaga atcttaaatt
    27241 ttatttagat gctccagttt ctaattcagg aaatttaaag tataggatat tagagcatgc
    27301 caaaacttgg ggaattgaaa ctgaagtaga attagtaaaa aatgcagatg ttgtattgga
    27361 aaaattagat agagtagtta gtagtgatgc agtcatagtt gacaagtgta taagttattt
    27421 taatgtggct agaggtataa ttgaagagta tattaaagaa tgtaatatca taaatttaaa
    27481 taaatagata aatataggtg agaatatata agtatatgta gcaatattct tagtaataca
    27541 agtaaagttt gaaaatagga gaacgaatac atatcgaatt tcataaaatg ttgtaaaaag
    27601 acatatgaga ggatggatat gtgtgaaatt aactaaacta aatattaaaa aatatagagc
    27661 acctatatat aaatatgctt tagcaaatat aaatttgagg tctgctaaat ctaccaattc
    27721 aagtatcata acagtaatac ctcagggagc caaaatggaa gtattggatg aggaagatga
    27781 ctggattaag gtgatgtaca attctcaaga aggatatgtg tataaggagt tggtatcagt
    27841 aagcgaatat gcttggagta acttaaactt aagagaagat aaatctacaa cttccaatat
    27901 aattacagta attcctgaaa aatctagggt tgaagtcctt caagtagatg gagattggag
    27961 taaggttgta tatgatgata aaataggata tgtttttaat tattttttat caattgatgg
    28021 gaataaacca aatgaattag attataagta tttttatact gacatgatta aatttgttaa
    28081 cgaaaataat attaaaagta ctagcgatta tctaattgta acagacctta gaaataaata
    28141 tacttatatt tttaagaaag ataatggagg atggggacaa ctttacaagt ggcaatgtac
    28201 tataggcaag cctgagactc caactataac aggtatattt tatataagtg gaagaaaacc
    28261 ttcttttgga acggatgagt attcagttaa gtatgctact agaattaaag gtggatatta
    28321 ctatcattct gtactatatg attcaacagg aagttatata atagatggca gacttggtga
    28381 agctcttagt catggatgta taagattaag tacggaaaat gcaaagtgga tatatgataa
    28441 tataccagat acaacaacag ttataattca ttaagaaaaa ttttgagttt tttattggga
    28501 taatgattct taaattaata ggattatata ttaacttctc ataaagagta ctatttaaaa
    28561 agtgtaataa gagagtgcta ttaacaaaac aaagatattt tgaggcactc tcttataaat
    28621 atacataatt aagatatttt cataaacaat tctataatct tatctttatc aaagaaaaca
    28681 ggattagcac cagcacaagc atctttcata gagttttctg caagcaattc aaaattagga
    28741 ttatcaacac ctacatcttt taaagatttt gggattccaa cctcttcaga aagagctttt
    28801 atcttatcta ttacaaagtc aacacactct ttatctgatt tattatttac atccattcca
    28861 ataacttcag ctattggtcg gaatttggca ggggctgatt tagcattttc ctcctcaact
    28921 attggaagta gcatggcatt acatactcca tgaggtaaat catataaacc tcctaattga
    28981 tgagccatag catgtacatt tccaagacct gcattactaa aggcaattcc atttaaaaaa
    29041 caagcataac acatttgttc tctagcttct atgtcattac catttttaac agctcttgga
    29101 aggtatttaa atatctgctt tatagcatat aaggcagttg aatctgtaac atcataagca
    29161 ccattagcta ctacagcttc tatagcatga gttagtgcat ccataccagt tgctgctgtt
    29221 aaattagatg gtttgctaat cattaattct gggtcattta ctgtcattgt ggctagtgaa
    29281 ttggtatcaa ccattatcat ctttacatgt ctgtcttcat cagttataac atagtttatt
    29341 gtaacttcag cagatgtacc agcagtagta gttatagcta tgataggaag acatttttta
    29401 gaagttttgt tgataccttc atagtctcta atatctcctc cattagtggc taatatagag
    29461 atagctttac cacagtcttg tggagaacca cctcctatag ttataacgaa gtcgcaattt
    29521 tctgatttta atattttaag tcctttattc acattagtta cagttggatt ttgtttaact
    29581 tcatcataaa caacaaagtc tatatctatc tgagataaaa tatctgttac tttttttaca
    29641 gtaccatttg aaactagaaa tttatcacta acaataaatg cttttttagt tcctaatgat
    29701 ttaattgaat ctttagcttc attaagacat cctttcccaa gtaaatttat tggtggtaca
    29761 taataaatgc tcataactaa aatctccttt tattttcatt gatttttatg taaaaatata
    29821 tatctaacaa ttttcactaa tttactcata atatatcgta tcttagattg agatagggtt
    29881 gctggttctt atataagaac ttaattcgta attacgatta tgattagaat ttaacatagt
    29941 atttttatca tgtcaataaa aatataaaaa atattataaa aaaaacaaag ttactgtagt
    30001 taaatcagca actttgtttt tatagtataa atcaaataaa tacattagtt taaaacaaaa
    30061 tttttaatta ttatgttttg atatcttcca tatacagaat attaatctaa tttattacaa
    30121 tgtcttcatt acgttcttcc atcattgatt gaatattttt ctgagcattt aagagtaatt
    30181 tttttatcag ttctattttt tcgtcattag ctctaaataa aggcagtgtt acactaacag
    30241 cagctcttat acatccattt tttcttattg gtacggcaag acattttagg tgttccattg
    30301 attcctcaca ctctgaagct atttgtgttc tttgaacttc aagaagctgg tcgtataaaa
    30361 catcaaaatc tgtaattgat ttttctgtaa aaccttttag accatctgga tataagctta
    30421 ttagtttttc cttgtcaaaa tcacataaaa gagcttttcc aagacctgta caattagcag
    30481 gtattttttt tccaacataa gaaataagtc taatcggttc tggagaatct acttttccaa
    30541 tataaagaac ttcattattg tcaagtatac caagctgaca agtttcagaa caggaattaa
    30601 ctatattagt catttcgtca attatatagt taaaaatagt tcttttttca aaaaatgaag
    30661 accctaatgt gtaagaacgt atccctatag aatatttgga tgtgttttta tcaatagtaa
    30721 tgtattttct agcattaagt gtatgaacta taggaaagat gctacttttt ggagcattga
    30781 taacatctgc tatttctgta agagtatatc cattttcgga ttctgctaat gcttctaaaa
    30841 tatctaatat cctagctgtt gggcgatgat tatctgaagt cataaatttc cccctctttt
    30901 tattaattta aagtattaga atatgttgat tttagcacac tatacgatat tttacaatgt
    30961 agaaaataaa tatgtaaatt tatatataaa taagctcttg atttagatac agatagatat
    31021 ttttttagac tgtacattaa ggaataacta atttccaaaa tatacctaaa gaaagtaagt
    31081 gatatttagt tatataattt aagtaaatat atgcaatagt tatttttata tgtaaatatc
    31141 aaaatattat gaacttatat tttatctatt ttttacactg tataaaaact ttatagtttt
    31201 gaatactata taattttaaa tacgctgtat ttttgcatat aaggaagtca tttgataata
    31261 tacaaggtat tatcagaaag tttgaaaaaa ttttgacaaa aatttatttt ttttattgac
    31321 tcataaatag gaaaatgcta tcattaattc aaagattcgt aattaaaaac ttagttctta
    31381 aatacgaacc gaaacggccg ttagaattaa agctaaaaac ttaataagag taattaaata
    31441 tcatgtttta ggaggattaa ctttatgata atggatttta ttaaaaaaat tcctgcaggt
    31501 atgatgatag tgccaatgtt tatagcagct ttcattaata ccttttgccc agatattgta
    31561 caaataggtt cgtttacgac agcagtattt tcaagtgttg ggtctgcaac tataattggg
    31621 gttcaactgg tatgcttggg aactcagctt caatttagag aaatgccaaa agttttaaag
    31681 agaggtggta tacttcttgg ttctaaattt gctataggtg ctttgatagg tatacttata
    31741 ggaaagctat ttggaatgga tggtgtcctt ggtctgacaa cattggctgt tataagtgca
    31801 gttacaaata gtaatggtag tatatatctt tcattgatga cttcatatgg agatgaaaca
    31861 gattgtgcaa ctatgagttt acttacttta aatgatggac cattttttac attaatagct
    31921 cttgggactt caggtcttgc aaatgtacca ttgttgtcat tattggctgc aatagtgcca
    31981 atacttgttg gtatgataat aggaaatttt gacaaaaaaa tgaaagagtt tttagagcca
    32041 gggtgtaatt tactcgtacc ttttgtaggg tttgcacttg gtagtagcat aaatcttgca
    32101 agtatactaa aaggaggttt atcaggagta ttacttggat taatatctgt atttgtagga
    32161 ggtatattta tagtattctg tgataaattt ataggaaaac gtccaggata tgcaggatgg
    32221 gctgtagcta caactgctgg aaatgcaatt gctgtacctg ctgctgttgc attagttgac
    32281 ccatcatggc aaccatatgt tgcaacagct acaacacaag tggcagccgc agtagttgtc
    32341 actgcaatat tagtacctct tataactagt tggtgggcta agaagtatgg atgtcctaag
    32401 ttcccaaaac aaaatgagga tggtacaata acagcttaat ttatattaca gtgagttgtt
    32461 ggtaaaataa taaattcttt aattagattt taggatatta ataaaattat attatttata
    32521 aaggagagca agaataatga taaatgcagt gataattgat gaaaaagata atgttgcagt
    32581 agctattgaa gcaatagcta aaggtagtga aattagtttt aaattaaaag acaaaacagt
    32641 aaaaacgatt acagcactag atgatataac tatttatcat aaattggcta taaaagatat
    32701 ggccaaaggt gataaagtta ctaaatatgg tgaacatata ggagaagcaa atcaggaaat
    32761 aaaaagtggc caacatgtac atattcataa tgttagaagt gttagagagg atttggataa
    32821 acaagttatg actaatatat aaaataatat ttatagagtt ataaaagttg tattcattgc
    32881 ttttagtgtc aaatagtttt taaataggtt tttagctgtt tgattagtga gtgtaataaa
    32941 aattataata tataaaaatt atagaaagta tatagactat tttaggagga aatcagtatg
    33001 aaattttatg gatataaaag accagatgga agagttggta taagaaacca catattaata
    33061 ttgcctacga gtgtgtgtgc atcagataca actagaataa tagcatcaca agttcaaggg
    33121 gcagttacct ttaataatca gaatggatgt tcacaagtac attcagacca acaattaact
    33181 atggatgtta tggctggtta tgcagcaaat ccaaatgtat atggtgtaat agttgtatct
    33241 ttgggatgcg aaaattgcca aaatgatttg gtagttgatg caataaaaga gagaacaaat
    33301 aagccaataa aaactcttgt aatacaagaa gaacatggaa ctttaaaaac tatagaaaaa
    33361 gctgttcgtt atgctagaga aatggcacaa gaagcttctt tgcttagaaa agaagaattt
    33421 ccaatatctg aacttatact aggaactgaa tgtggtgggt ctgacccaac aagtggatta
    33481 gcagcaaatc cattaatagg tgaattaagt gataaacttg tcgatttagg agcaacatca
    33541 attttaagtg aaactactga atttataggt gcagagcata tactagctag gagagcagta
    33601 aatgaagaag taaaagaaaa aatattacat atagtacata gatatgaaaa ttcattaaaa
    33661 ttggttggag aagaagttag agaaggtaat ccatctcctg gaaatatagc tggtggttta
    33721 acaagtttag aagaaaaatc acttggttgt atacataaag gtggtcatag acaaataagt
    33781 gaagtatatg attatgccaa acaaattgat aagaaaggtc ttgttataat ggatacccct
    33841 ggaaatgatg cttcatctgt tgctggtatg gtagcaggag gagcacaaat agtggtattt
    33901 agtacaggaa gaggaacacc atcaggaaat ccaatagcac cagtaataaa aataactgga
    33961 aataaaataa cttttgcaaa tatggaagat aatatggatt ttgatgctag tccagttatc
    34021 tatggtccac aaacaatgga agaattaaca gatgatttgt taaatatggt tgtagatgta
    34081 gcaaatggaa aacaatcaaa agcagagtcc cttggatata ctgaaatggc aatagctaga
    34141 gtatgcaact atgtataatc tttaagtaag aaaataaata catagaattt taataaaggg
    34201 tgagattatg aagtttgtaa gttttactga aggagaaaat gaatgtaaaa gaactggagt
    34261 tttttctaaa gatgaattat ttattataga tgttaactct ttaaatctca gtagaaattt
    34321 taaggattta aatgaattaa ttcaaaatgt atctagtgaa gatattatta agttgaaaac
    34381 tattataaat gaaagtacat tctataatta tgatgttttt aaaagagaga gatgtacggt
    34441 acatgttcct atagaaaaac caatacatga tatcttatgt gtgggagtga actataaaga
    34501 ccatcttgaa gaaactcaaa ctcactttga tgatagtttt gaagaaccac aaaaaacggt
    34561 ttattttaca aaacgtgtga caaaggcaat aggtccagaa gatgagatag atggtcattt
    34621 tgagataaat aatcaactag actatgaagt tgaacttgga gtagtaatag gtaaaacagg
    34681 tgttaatatt agaaaagaag aggtagaaga ttatatcttt ggttacactg ttataaatga
    34741 tatttctgct agaaagttgc aaaaagaaca tgttcaatgg tttagaggaa aaggattaga
    34801 tacatttacc tctttaggtc catgtatttt acataaaagt gcagttcctt ttcctataaa
    34861 acttaaagta tgtagtaggg taaatggtga agaaagacaa agttctaata caggattatt
    34921 catatcagac gtttcagaca tagtttcaga actttcaaaa ggtatgacct tagaggctgg
    34981 agacattata gctactggaa caccttctgg agtagggatg ggattttcac ctcctcgata
    35041 tatgagtagt ggagatgtag ttgaatgtga gattgagagt attggaattt taaaaaatta
    35101 cattaagtaa ctgttttaat ataattaata ttaaagctaa atctgatgta ttaatgaaca
    35161 tattaaaata aattttagga gtttaaatta tgaaagcaga atttttgaca ccagttgtta
    35221 caatatttga tgaagaagga aatttagata aagaaggtaa taaaaaagtg tatgaccatc
    35281 ttatagatgg aggtgtagat ggactagtca taatgggaag tactggagag ttctttaata
    35341 tgtctatgga tatgcaaaaa gaacttatag atttagtaac tagtcatgta aataagagag
    35401 taaaagtgtt tataggtaca agtcgtatgt gtataaatga atctatagaa ctttcaaact
    35461 atgcacataa tagtggagca gatggtgtta tgataataag cccttattat ttctctcttg
    35521 atgatgatag tattgagtta ttttatagtg aaatagctaa gaatacagag gctgaaatat
    35581 atttgtacaa ttatccagat agaactggtt atgatttaag tccagaactt acattaagac
    35641 ttgcaagaaa acataaaaac atagttggat ataaggatac agtaactttg atgggacata
    35701 ccagagattt aataaatact atgaaaatag agttcccaga atttaaggtt tatagtggtt
    35761 atgatgaaaa ctttatacat aatctaatgt ctgggggagc aggttgtata ggggggttat
    35821 caaatttaat tccagaagtt tgctccaaat gggctgaagc ttacaataat agagatatgg
    35881 agaaggttat agaaattcaa aaatatatta ataaagcaat ggatttttac ttaataacca
    35941 atccatttat accagcaatg aaaaaagcta tgaatatcag agggttacaa ataagtgatt
    36001 atatgactgc tccatttgta aaaccaaatg aaaaacaagt atgtgaaatt aaaaaattga
    36061 tgaatgaatt aaatatatgt taaatcaacc ttgcaaagag gtcaacaata aattacaatt
    36121 atcttaataa aaattaaatt aaaataatac tagggtacta tattagttta atagggaaag
    36181 tgatgaaaat tcactacagc ccccgctact gtatacggat acgaaatcaa aatccactga
    36241 aatttataaa aattttggga agggtgatgg aggaaaagcc gtgagtcagg agacctgccc
    36301 agtattatat aagttcaatt tagggtggag attgtaattt ataataaaat gaagtatcaa
    36361 ttcgtttttg taaagttgat atatgaactt ctccttatta aattaggaga agttttttat
    36421 tttattaaaa ggttatactt attaaagatg actttaggat aactttaata agtatacttt
    36481 aaaaagcata tattattaaa gttttttagc cactcataaa aaataagata ttggagtgaa
    36541 agagatgaaa tttaaatcaa atgttttaaa gcagtttttt ttaattgcta tggtaatttt
    36601 tatggtagga ggtcttatag ggtgtagtaa aagtgacaaa gagaataaac aagctagtac
    36661 tggtaagaaa ttagaattaa aatatgctag tggatttagt gttgaagatt tagaagatgg
    36721 aattaaaaaa gtaactgatg gagataatcg agaactgatt ttaatcccaa agaagattaa
    36781 aattcctgaa aaatataaaa atgctaatat agttagaacg cctgtggaca atgtattaat
    36841 agcatctaca acacaggctt gttctctgag aacaatagat gaactagata gtataaaagc
    36901 cgtaacaaca gaagagcagt actggactat taaagaaatt aaagatttaa tgaaagatgg
    36961 aaaaatacat tacgttggtt caaatttagc accagattat gaaaaaatag tagacttaaa
    37021 tcctgactta actatagtga gtagtggttt atcagaggct gatacaaaat ttattgacaa
    37081 attaaaagaa ttagggctta attatgttgt agacaatgag tataaagagc aaaatccatt
    37141 tggaagaatg gagtggacaa gtttaatagc tgcattttat gataaagaag atatggctac
    37201 tagtgaacta aataaaactg tacaaaaggt agaagaagta agtaaaaaaa taaaaaacaa
    37261 agctaaacct aaagttgtat gggcatctgt atatgaagga agtgcttata tagctcctaa
    37321 agattcatat gtggataata tgataaaaat ggctggtgga ataaatgcat gtgcttcaat
    37381 agattcaaat gaagggcgag taagtattga acaattgcat gaagttgcaa aagatgcaga
    37441 tatatttgta tactcatcaa gttcagatta tgcaccaaat ttagattcta taaaatctag
    37501 tgcacctgta ttggctgatt tggatgttgt aaaaaacggg aacctatggg tgtttgctcc
    37561 agattattat caatcagtag ataagacgga cgaattaata gtagatttag ttgagatgtt
    37621 ccacccaggt actacaggtg aaaaaatcaa acattatata aattatgata aatagtacag
    37681 agaggacaca aaaagatagg ttttatagat tttagttaat atagctttgc taagaggagt
    37741 atacaaatgg attttatcaa taaaatgaga ataaggaata caacaatatt tatagtatta
    37801 attataagta tgatacttac ttttttagtg tgtgtagcat ttggctctgt aaaaattgaa
    37861 tttaaagaag taatagatgt tgtattaaga ggtatggata atacagaaca ttataaaata
    37921 atatacaata taagaatccc tagagtactt gcaaccatgg taggtggagc atgcctagca
    37981 gtatcaggta ttttattaca gatatttttt aaaaacccaa tagttgaacc gtatatatta
    38041 ggagtatctt caggttctac tttatcagta gctctcatga ttttgggagg atacacattg
    38101 ggatttgaga gtgtaaattc aatgagtata tttgtagcag cttttatagg agctttaatt
    38161 gtaatgtcta tagtcatttt atttgcaaat aaggtaaaga atataacaac tcttttaata
    38221 ataggaatta tgaccggata tgtatgtagt ggtataacaa atgtgttaca atcatttgca
    38281 aatagtgata aattaaaaga atttactatg tggtctatgg gaagtttttc tggatttaca
    38341 tgggaaaagg tagaaatact tataatagtt ggtatattag gtcttttgat gactgtattc
    38401 ataataaaac ctttaaatgc ttttttacta ggagaagagt atgcaaaaag tattggcata
    38461 aatataagat tttttagagt tttgatagta tttatatcta gtatattagc agcaatagta
    38521 tcagcatttg caggacctat agggtttatt ggacttgcag tgccacaaat ttcaaaaatg
    38581 atatttaaaa catcagataa tagagttttg ataccagtag taatattttt aggcagtata
    38641 gttacagctc tttgtgattt aatatcaaga gtaattttat caccagtaga attaccaata
    38701 agtacgataa catctttatt aggagctcca attgtagtaa tgttattggt gaaaaggaag
    38761 gatagggctt agacatgttg aaaactaata atttaagtgt aggatacaat aacaaagttg
    38821 ttataagtaa tataaatgta gaagtaaaaa atggagaaat actatgtctt ttgggaagta
    38881 atggagctgg aaaaactacc ctattaaggt ccttatctaa acttatatca ccaataaaag
    38941 gtgaaatata tttgaatggt gtaaacataa actgtatatc aagaaaagca ttatcaaaaa
    39001 aaatggcttt agtacttaca aatagattat taggtgattt aatgactgta caagatatag
    39061 tcaatatagg aaggtatcca tatacaggat tttttgggag tctatctaag aaagatttaa
    39121 taatggtaga tgaagcattg gagtctgtag atgccttaca tttaaagaaa agatattttg
    39181 atgaactaag tgatggagaa aaacaaaagg tgttggttgc aagggctctt gttcaagaac
    39241 cagaaataat tatattagat gagcctacaa ctcacttgga tataaaacat agattggaac
    39301 tcataaacat actgaaaaaa ttaagtaaag aaaagtcaat atcagtaata ctttcattgc
    39361 atgaaataga catagcatta aaaagttgtg ataaagttgc tcttataaaa aataataaag
    39421 tcatagctta tggtcagcct gaagatgtag tagatgagga tattataaat tcgctttatg
    39481 aattggatga taaaaacttt aatagtcttt taggttcagt agaaattagt aataaatcta
    39541 aaaatgaagt ttttataatt ggtggtgggg gtaaagcaac accaatttat agagctttta
    39601 ctaaaaaagg tataggtctg tattctggaa taatacatga aaatgatatt gattatgaaa
    39661 ttggtagaac tatggggata aagatgttta cagaaaatcc atttgagcct ataagtgatg
    39721 agagtttcaa tttggctatt agaaatttaa atgattccaa gattataata gatacaggat
    39781 ttagtgtagg agagacaaat aagaggaata tagatattat aaaagaggct ttaaaattgg
    39841 ataaaaaagt ttattctttt agaaatagag atgagagtaa gaagtattat gacagtttgg
    39901 atagtaagat agaacatata gataaagttt ctcaaataat caatagtgca gatataaata
    39961 atttattata atttatgaaa taaaatgtac ttatgtgcta tagaaaaaag agtatagatt
    40021 ataatttttt tgaaattaca atctatactc ttttgttatt ttgtttatgt atttatatat
    40081 ttataaaact ttagcatttt atagataacc aatagcttcc tctctagtta aaaaaaagtg
    40141 aatccctgta gtcgattctt tccatctatt ttcattaaaa tcttcagcta caatcgtttc
    40201 tcctactcta tatataaaat tttcatcagc atatgcacga gcacttttaa aagattcttt
    40261 accatctata ctagtaattg acagtacttt tgccttatca catctacaag cgtttgatgt
    40321 agcagacact ctttttgcgt cgctgggtat taataattgt accattctaa aattaaaaca
    40381 ttttttatag cctataaatg ctcctgtttc aggacaatac aatttaaaaa aacgggtact
    40441 ttcatctgat attactccat ttaaagtagc atgttctaaa tttgaatttt ctaaattagc
    40501 tcctctaata tctgagttag ataagtcaca aaatctaaaa cttgcaccac ttaagtctgc
    40561 attttttaat atagaatttt ttaatgaaca atccgaaaga taagaattat taaaaataga
    40621 gttttctaaa tctgcttttt ctaaatttaa attgataagg tcagaccacg aaaagtcaat
    40681 attacttaag cagtatcctc ttaagtccat attttctaat cttaattctt ttaaatctgc
    40741 cttttctcca gcattattgt ttttaagcca taaataatgt ttctcaagtg ttttttctaa
    40801 ttcttgttta gaaatagttt tcattaaaat caccttcata aatttatttt tatatatgta
    40861 gtagcaaaat agtcatatat ttaattatat aacaataaat aaaaaacttc taaataatat
    40921 ataaaatatc atcttgaaag tacttttttc aatatatcag aatatatttt taagctattt
    40981 agagata
//
LOCUS       DAEPKC010000025        40914 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.025, whole genome shotgun sequence.
ACCESSION   DAEPKC010000025 DAEPKC010000000
VERSION     DAEPKC010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 40914)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40914)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40914
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.025"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            167..1177
                     /locus_tag="KR294_001400"
     CDS             167..1177
                     /locus_tag="KR294_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4116 domain-containing protein"
                     /protein_id="HBH0239482.1"
                     /translation="MHEDKNDIFESIDTEDFDNKTEEECLELVRKNGLNLIYIKNQTE
                     EICLEAVRQNCNAIKCVQNQTEKICIEAVKQDWRMLEFVEEPTEEICMLAINQDGTAL
                     KYIENQTEELCLRAVEKNGAALEYVKEQTEEICIEAVRNSEFGLARVKNQTEKICMEA
                     VKHCSYNLKWVENQTEEICMEAVRQNGLDLKFVKNQTETICLRAVRQNGMALEFVKEQ
                     TVGICLKAVRQYGMALKFVKEQTEEICTEAIKQDKRALSFVKGDKEKYKALYDNNEPF
                     AKRYVRNVIEKENRALIKKGEENAKIKIAGKLYDRGMSFEDISDIVEIEISKLKVSLG
                     VF"
     gene            1288..1776
                     /locus_tag="KR294_001401"
     CDS             1288..1776
                     /locus_tag="KR294_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBH0239483.1"
                     /translation="MKITVLYQTRSGNTERVAKLIEEGAKKVDGVDVKLMRLDNIDLD
                     YLNESKAVIFGTPTYLANTTWEVKKWFDEDSKKVNLAGKLGAVFATCDYICGGPDVAI
                     LTIVGHLMVKGMLVYSGGGSLGKPFIHLGHVHSIEGPELQDEKAIIFGERIATKAKEL
                     FA"
     gene            1952..3880
                     /locus_tag="KR294_001402"
     CDS             1952..3880
                     /locus_tag="KR294_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBH0239484.1"
                     /translation="MVWHIEYEIFSAIIVIFLMVYFFRSKFIPTLQNKIYCALLIFSF
                     LFIISNILGSFCLNNIDKIPIFITFLLNQIYLLLLPIPAALVSFYVMAIIYQDIRYMK
                     KRLLFLSIPLIICIILSITNPFTHILFGLSKETGYIRGCGYVATFASFFFYAIYSAFL
                     SFKYRKAMHESKIWAIRGFLIVSIVAIILQAIFLQYLLTGTACACSLLLTYLSMQNRG
                     LIIDDLTGVLNRQSFIQELDLNINTEQSGFIITIALDDFKFMNETFGTKNGDIALKEV
                     GKYLIQIHDVNHVYRIGGDIFSIVVNSQLGIEPDDIIRKIEERFKKPWLVEEISFNLA
                     TSIAVVYYPENAETTEDVIVAIDFSIHEAKRSESRRVVYADASISEKIKKKHVIKNCL
                     KEALKNDGFEVYYQPIFSNSRGRFTSAEALLRLEHKELGFIPPDEFIPIAEQTGLINS
                     IGLVVFEKVCRFIASDEFEDLKLDNIAVNLSVVQCMQKNLADDLLYLMNKYNVSPTKF
                     KLEITETVAMGSFNIIKETMERLIDLGVKFALDDFGIAYSGVTNMLSLPFSVIKLDKS
                     LIWSMNEDSRHKLTVETIIALINKLNMKAVAEGVETIKCAEDLIAMECEYLQGYYFSK
                     PVPEDVFKNLLKENTFTS"
     gene            4057..4467
                     /locus_tag="KR294_001403"
     CDS             4057..4467
                     /locus_tag="KR294_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBH0239485.1"
                     /translation="MNKKKILVPIDGTERSMHSLEFIKGIFKKDEVEVEIMNVKELVF
                     IDGISLAEEIKNSENLGRRILDKAAEIMGEYDVKVHFTFGYPGDEIIRKAKEDNVDFI
                     VMTKSTKKGLTRMIGSVTASVVKQAKCIVMIVPE"
     gene            4489..4791
                     /locus_tag="KR294_001404"
     CDS             4489..4791
                     /locus_tag="KR294_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIBC"
                     /protein_id="HBH0239486.1"
                     /translation="MNKKIVAVCESERSLNSLKTAANDLGFDLVYEIQENDNIKNELS
                     IYDIEDASIVLFVTSDSIESIEKIDRFIDREFYEVDPKYIIEDAKSIVSEILIDLN"
     gene            complement(5008..5700)
                     /locus_tag="KR294_001405"
     CDS             complement(5008..5700)
                     /locus_tag="KR294_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HBH0239487.1"
                     /translation="MKSLNATEKIIDYIKLNILNGTFKINSKLPSERKIADLFNISRI
                     PVRNAINILCKEGILRAVPYSSPIVEGFKKVDLFDDGEIYKNHNIQEFYVESLRARQL
                     IESEATKLAILNATSKELQKIKYTYLKSIEELDKVSHGLIEECYDADLQFHKEIILAS
                     HNPIFIKYYELIPKTVSSNQYFGFKYRNSLKDMISHHNKIMIAFDSKDSYLGYTSMYN
                     HLEDVIQLFQHD"
     gene            complement(5726..6913)
                     /locus_tag="KR294_001406"
     CDS             complement(5726..6913)
                     /locus_tag="KR294_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH0239488.1"
                     /translation="MKKISNQKLLLLSIVTFFWFSQYVYIPFQNPYLSACNVSTNMIG
                     IIIGAYGISQCLLRLPVGVFADSINKHKIFILSGIFFAGLASLIRVFSPGGNGFLIAN
                     ILSGISSSTWISYMVHYTNFFSTEHQQKATSTIILVNNLGMLIGFVMSTLFYEKLGMT
                     ALCIMSVLSSVIGTILALNIKNHNSKKIPEKISIKKYLSICKDKRLVFFSFMALIQQG
                     IQMSTTMSFTTQILKNLGSSSTLIGLSSIFYMVCAVASSGFASTKFCTKYGPKFWIPL
                     VFILVSAYCFLVPTIKNINIIFVLQVLPGISTGILLSYLTSESMKNVPKHQKSTAMGF
                     FQAIYAIGMSVFPMIVGKISEYTSIQYGYFILAIIAILASILSYTYYKKVDLTLNYDI
                     IQS"
     gene            7249..9126
                     /locus_tag="KR294_001407"
     CDS             7249..9126
                     /locus_tag="KR294_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBH0239489.1"
                     /translation="MDYKNIAQEILLNVGGKENVNEVTHCMTRLRFKVKSASKVNKDK
                     LSKTEGVITVVESMGQIQVVIGNKVKKVYDEVIKIVPQSNNVGKKNESQEKQGIINSI
                     LSAVAGIFTPTIPAIAGVGMIKGILSVLAMYYMNKNGVDIKETQSYIILNALADSIFY
                     FMPIILGYTAAKVFNANKIISMVLGATLCYPTFTALMAGEESVRFLGLAVTKATYTSS
                     VIPIIIAIWALSYVEKVLEKYIPEVIKIIMVPTLSLVVMLPATLFLFGPIGIYIGNVI
                     NFSYKYIYELSPALCGAFVGGLWCVLVIFGAHRALLPIGISDVAQTGRQNLLAFAGAA
                     NFSQAGAALGVFFKTKNQGLKTISMSATITALFGITEPAIYGANLRLKKPMVCAVICG
                     AFGGAIMGMGGAYGNAFANQGVLTIPVYAEAGALGFLSYLGGCAIAFFGSAISTYLVG
                     FEDLEESSNKENSSIKVETKDGVIDITSPVEGECIELSEVKDDVFASKAMGEGIAVLP
                     TKGVITAPTDCEVASLFPTLHAIGLKLDNGAEMLIHVGINTVELNGKYFTKHVNQGDL
                     VKKGDKLISFDIDKIKKVGYDVTTPVIVNNTFDFGQVVSCKSSYVSTNDNIISLVLAG
                     N"
     gene            9436..10842
                     /locus_tag="KR294_001408"
     CDS             9436..10842
                     /locus_tag="KR294_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBH0239490.1"
                     /translation="MNTGFPKDFLWGASSSAFQVEGAWDKDNKGKTVADYNSFKKSHL
                     QADTKVASDFYHNYEEDIELMKELGMKTYRFSISWARIIPDGEGEINQKGLDFYNKII
                     DKLIECDIEPFVTLYHFDLPFKLVEKYNGWESRETVYAFERFAKICFKHFGDRVKYWQ
                     PHNEQNLIVRVEERINIYDETDSWKIDKMRAQMDYNLCLAHALAVNACHEMIKESKIG
                     AAVSSSVTYPLTSKPEDIYAARMNDNFKVYYMLDMHHYGEYPGYYMKYLEKRNIVPHM
                     EDGDKEILKKAKMDFIAVNYYRTNCAEALPEDSQHPFGLREGTVDFSMYGLFKMSMNP
                     NLEASEYGAAIDPSGLRVALNEYWQRYHLPVIITENGLGAKDILEDGKIHDDYRIDYL
                     RSHINACKLAIEDGVEMIGYCPWSFTDLLSSSQGFNKRYGLVYINRTDHEILDLKRIK
                     KDSFYWYKEVIENNGIVK"
     gene            10870..11718
                     /locus_tag="KR294_001409"
     CDS             10870..11718
                     /locus_tag="KR294_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBH0239491.1"
                     /translation="MYITKVLNNSLLLAKDDNDEEIILMGKGIGHNYKAGSELNEKDI
                     EKIFVLHDENIKKSIIQLATEIDAEYFGIAQMIIAYGIEKYNLKLMNHIYLALTDHIA
                     FAVRRFKEGIMIENHYLFEIKEFNPKEYDIGKYAITVFKEVLGLDLPEEEIGNIAGHF
                     INAQQDNPYSDRNKRSAKIVNAILQIVHYHFSIVYNKESFYYRRFVMHLKAFSQRFLA
                     NEPSREKIDFIYEQVQKNCKEEYECVKKVGAYMYKEYSRELPRQEELYLMIHIHKILG
                     ELCENS"
     gene            12220..12912
                     /locus_tag="KR294_001410"
     CDS             12220..12912
                     /locus_tag="KR294_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003020373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0239492.1"
                     /translation="MNKVLIIDDDKDLCILLKKSISIEQIEANYCHSGRDGLVELSKQ
                     DYQLVVLDVMMPGMDGFETMEQIRKYSSIPILMLTSKSDNYSKVHGLRAGADDYLTKP
                     FEITEFTARVLSLIRRYTRFNPKNEEPQQLSFKGLLIDLDQHTVTTNGEPMLLPPKEF
                     GVLLYCARHQGKILTKQQIYEAVWGEPYVYDDSNIMAIISRLRKKIELDPSSPIYLQT
                     IKGIGYQFNTEV"
     gene            12909..13844
                     /locus_tag="KR294_001411"
     CDS             12909..13844
                     /locus_tag="KR294_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH0239493.1"
                     /translation="MKMDEQTIILFLLLLSIGLLFLSIFAFSKLGHIHKRLKDIEEIL
                     ADVQIGDENRKILIKPCDVMAPLVYQLNEIVYDYENKLLSLKKSDKASKQLMTSLSHD
                     VRTPLTTLIGYLDAVHSGIVIEQEREEYLEIARRRAYDLKDYIDVLFDWFRLNSDEFT
                     LSIESVEIAELSRNILKDWIPIFHEKKLNFEIDIPENRLMVNLDPDGYSRVVNNLVQN
                     VLAHSKARQIKITMSEDSRMVLLRVEDDGVGIARENLPHIFERLYKCDKGRSEKGSGL
                     GLSIVSQMVERMGGQVSVESEIGKYTVFTVSLPLI"
     gene            13992..14915
                     /locus_tag="KR294_001412"
     CDS             13992..14915
                     /locus_tag="KR294_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013273760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0239494.1"
                     /translation="MNNLIIETKNLTKQYGAQKSVSNLNIHVQKGRIYGLLGRNGAGK
                     TTTMKMLLGLTKPTTGEIKIFGQDIHNNEKKLLPRIGCLIESPGFYPNLTGTENLKIF
                     ARLRGIPKKNAVESALDVVGLPNNDKKLFSQYSLGMKQRLAIALAIMHDPQLLILDEP
                     INGLDPIGIAEVRTFIRDLCTERGKTILISSHILSEIALLADDIGIIDHGILLEEESL
                     AQLEEKNSKYIHFAVSDAAQAARLLETQLNLKNFKVADNYNIMLYDTDVSVAEINRAF
                     ILNNIEVSESHLCEDTLEDYFKKVTGGEGIA"
     gene            14899..15669
                     /locus_tag="KR294_001413"
     CDS             14899..15669
                     /locus_tag="KR294_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0239495.1"
                     /translation="MKELLDIISCEFSKLKRLKFILISILGACLFPIPATILIAKDNL
                     PFEQLFKLVVNFGYFLLLPIVLSIVASQLFFIERDNDVLKNLATVPVPKGKLALAKLA
                     VLLFISLFYSVAGLGATIIGGFIVGIVEGVAVKLGMSIAFGIMFFVTVLPVVVLIVYF
                     NRSYIFSIILSFVYAIFNFSISLNIINFEPNNPLLSVLPAPVIMRWWMAFWGDPTGEY
                     TVLRQPYLLSTPACVGILCLITIIAVLLICMIYKKQEN"
     gene            15679..16461
                     /locus_tag="KR294_001414"
     CDS             15679..16461
                     /locus_tag="KR294_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0239496.1"
                     /translation="MLDIITTEFQKIKRYNILWIGVVAVLFSALLAVFQVVSSHGSDP
                     LTYESFANGVIWNNFSLSFPFGITLIGGYLINREYTDQTLKNILTVPISLRKLLVGKL
                     IAVGGITVLLSLFSFLCTFILGLLFCNINISVILVVKSLVQILSVNLYCYVAVLPIIA
                     YFGRKQNAFLTGVGIAFVYGFCGVFVAGRNLTDFYPITAGLGLVGYNNGAGTVYQPLI
                     GAMTLIVILILTTILLVFTPNYDKVMTISKKKGIKHKKYSHK"
     gene            16838..17374
                     /locus_tag="KR294_001415"
     CDS             16838..17374
                     /locus_tag="KR294_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rubrerythrin family protein"
                     /protein_id="HBH0239497.1"
                     /translation="MNLKGTKTEKNLMAGFAGESEARNKYTYYASKARKEGYNQIAAI
                     FEETANNEKEHAKLWFKLLHDGMPSTEENLKDAAAGENYEWTDMYAKFAKEAREEGFD
                     KIAYLFEAVGKIEKEHEERYLKLLENLNEGKIFKRDEEVVWQCQNCGHVYVGTEAPEK
                     CPVCDHPKAYFNIKAENY"
     gene            17406..17795
                     /locus_tag="KR294_001416"
     CDS             17406..17795
                     /locus_tag="KR294_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBH0239498.1"
                     /translation="MKFSKQRELILNEILNNPVHPTADYLYENLKKDNPNLSLGTVYR
                     NLAQLTEHGFIRKVSIPGYPDRFDGRIDNHYHIICEVCGEVYDLESEVLNNLQELISE
                     ETDIKITSYNISFKGICNNCKRCSQVG"
     gene            17832..18218
                     /locus_tag="KR294_001417"
     CDS             17832..18218
                     /locus_tag="KR294_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="desulfoferrodoxin"
                     /protein_id="HBH0239499.1"
                     /translation="MCSEQKFFICETCGNLVGMIQSGGVPIFCCGKPMKELVPNTTDA
                     AVEKHVPVIEVDGNNVTVKVSSTTHPMTKEHHIAWVYLMTEQGGQRKCLAVDGEPVVK
                     FALNDDDKVISAYAYCNLHGLWKAEL"
     gene            18345..19787
                     /locus_tag="KR294_001418"
     CDS             18345..19787
                     /locus_tag="KR294_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HBH0239500.1"
                     /translation="MSIYKCSVCGYIYDESKNDKTWDELSEDWECPVCTKGRSYFGKI
                     STVYYEEDEKIAEDIVEDESKLNTEKEGDLNYLSTYLRRDDEVEKHMDIIHEMAVTGK
                     SIIEPMRTKLPVISWDDILIMGAQLNPLPLNEHDEVNTTTIIGKKAKKPMIIENPVYI
                     SHMSFGALSKELKIALAKGAAQNKTAMCSGEGGILPEEKEASYKYIFEYVPNKYSVTE
                     ENLKNSDAIEIKIGQGTKPGMGGHLPGEKVTEEIAKVRNKPVGQDVISPSCFEEIQSK
                     EDLKKLVDELREVSEGRPIGVKISAGHIEKDMEFIAYAKPDFVTIDGRGGATGASPKL
                     LKDATSIPTIFALYRARKYIDTHGLDIDLVITGGLRISTDFAKAIAMGADAVAIASSA
                     LMAAACQQYRICGSGKCPVGVATQDEELRKRLHIENSANRVANFLNVSLEELKTFARI
                     SGHKDIHDLSVDDLYTVNSEISNYTNIQHV"
     gene            20084..20899
                     /locus_tag="KR294_001419"
     CDS             20084..20899
                     /locus_tag="KR294_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBH0239501.1"
                     /translation="MERLKIQVLVDNNTYIDRYFVGEPAVSYYIEIDGNRILFDSGYS
                     DVFISNAEKLNIDLGNLTHVVFSHGHNDHTRGIQFLENRYDLSTVELISHPNCFIPRK
                     HGEKSIGAPFSAEEIKNIFMYNPKDKPFNLSKNCVFLGEIPSINDFEKRAKIGKCKIG
                     DLWEDDYVLDDSAIVCKTDKGIFIVTGCSHSGICNIVEYAKKVCGDDRVIGILGGFHL
                     FELNNRLDSTIQYLDKEEIRMLYPCHCVSFKVKAKMNEILNINEVGVGLTISI"
     gene            21501..22685
                     /locus_tag="KR294_001420"
     CDS             21501..22685
                     /locus_tag="KR294_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239502.1"
                     /translation="MQKSVKKAKVTGSMLAIFGVASVLFSSHAGGGFATGNQETQYYV
                     QYGWTAPLMAILAMIILTATMREVIIMYNNNNCRNYKDLFCELWRPYPKLEIIWEIYY
                     YLMVLIAVSAVIAGAAAVFQSIGVNYFVAVFIIGVVLLVFTIFGAMLVSKAATAMTIA
                     ILVCTLTIFIVGIKAKVPEITEILSNRTSFTPGYIKPILNTFIYAGFQSVVIPTLAGC
                     SRPLLKNSKEATKAMIISFVMNAIALGLAVTMLMGWYREIIAAGQTTLPTLYVAGQSG
                     NHTIYIIYNVALFLCLMSTGVTTIFGLVNRFEDHKALSFLSSRMKRRVFTACAIMVVS
                     MLISLTGLSNIVKYGYGYCGYLGLFTIVIPFLTLGHYKNKKFAKENPEAKWPAELNEN
                     VN"
     gene            complement(23062..24171)
                     /locus_tag="KR294_001421"
     CDS             complement(23062..24171)
                     /locus_tag="KR294_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBH0239503.1"
                     /translation="MDFKSLGISENTINILKKSGITTPTPIQKESIKLIKEGKDVIAE
                     AQTGTGKTLAFLLPIFENISLDINDIQVLILSPTRELAIQITEEAMKLKESKDVSILA
                     AYGGKDIGSQIKKLKGNIHMIIATPGRLLDHLNRKTIDLSKLKTFVLDEADQMLLMGF
                     KNEVEAILKETSNKKQTLCFSATINSQVKKLAYRYTKNPVVVSIQKEEITLNNIKQEV
                     VETTDRKKLDALCKVLDEDNPFMAIIFCRTKRRVDNLEEALAIRGYNCQKLHSDIAQS
                     KRERIMKSFRNLDIQYLIATDVASRGLDISGVSHIYNYDLPETPEDYIHRIGRTGRAG
                     EEGYTCAFIDPKNERMLSEIETAIESKISRRIIEL"
     gene            24633..25826
                     /gene="nifV"
                     /locus_tag="KR294_001422"
     CDS             24633..25826
                     /gene="nifV"
                     /locus_tag="KR294_001422"
                     /EC_number="2.3.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homocitrate synthase"
                     /protein_id="HBH0239504.1"
                     /translation="MCVISKDRAKEIKIVDTTLRDGEQTAGVVFANREKIMIAEMLSD
                     LGVDQIEVGIPTMGGDEKNVIKHICSRNLKSDIMAWNRAVIKDVEESISCGVDAVAIS
                     ISVSDIHIENKLRTSRGWVLENMAKTVEFAKKNGLYVSVNGEDASRADIDFLTEFINV
                     GKQAGADRFRYCDTVGVMNPFSIKNAIETLYERTNFDIEMHTHNDFGMATANALAGIA
                     AGANYVGVTVNGLGERAGNAALEEVLMALKCVYKCDLNNIDTRKFRGICEYVAQASGR
                     ILPTWKPVVGDNMFIHESGIHADGALKDPHNYEPFDPSEVNLERKIVIGKHSGRAAVV
                     NKLSEYEMYISPENATKLLNAIRATSIRLKRSLMDKEILQLYCDILAHEKGTTEEEAV
                     RGSYI"
     gene            25851..27776
                     /locus_tag="KR294_001423"
     CDS             25851..27776
                     /locus_tag="KR294_001423"
                     /EC_number="4.2.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aconitate hydratase"
                     /protein_id="HBH0239505.1"
                     /translation="MGDNIVYKIIKKHIVDGEAVAGSSIGIKIDQTLTQDSTGTMTYL
                     QLEAMGIDKVKTKRSVAFVDHNMLQQGFENADDHKYIQTVADKYGVYFSKPGNGICHQ
                     VFLERFSTPGDTLLGSDSHTPTAGGVGMMAIGAGGLDVALAMAGGAYYIKAPKVCKVN
                     LVGKLNNMVSSKDIILEVLRKQTVKGGVGKVYEYGGEGVKSLSVPQRATITNMGAELG
                     ATTSIFPSDEKTLEFFKSQGREEAWIELKPDADAVYDEEITINLDELKPLAAKPHSPD
                     NVDEVENIGKIKIDQVAIGSCTNSSYEDLMKVAQILKGNKVHKDVSLVIAPGSRQVME
                     MIARNGALADIISAGARILENSCGPCIGMGQSPGTDSVSLRTFNRNFYGRSGTLSAQV
                     YLVSPEVAAVSAIKGVLTDPREFDIKFTNLDVNEFLIDDSMIIKPADVGSDVEVVRGP
                     NIKPFPLNTELSQSIGGKVILKTEDNITTDHIMPSNAKLLPFRSNIPYLANYCFNTVD
                     TEFPQRAKDNNGGFIVGGDNYGQGSSREHAALAPLYLGVKGVIVKSFARIHKANLINS
                     GIIPMEFCDEKDYENISLLDNLEIPNILDNLGSGILEVKNTTKGTSFKVKVELSAKEV
                     DVLKAGGKLNYTKNQAN"
     gene            27798..28793
                     /locus_tag="KR294_001424"
     CDS             27798..28793
                     /locus_tag="KR294_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isocitrate/isopropylmalate dehydrogenase family
                     protein"
                     /protein_id="HBH0239506.1"
                     /translation="MYKVTLIPGDGIGPEVAKAMKKVVEATGVEIEWEEVNAGEAVIE
                     EYGTPLPEYIIDSIKKNKIAIKGPITTPVGKGFRSVNVTLRQALDLYVNLRPIKSFKG
                     IKSRYEDVDLVVVRENTEDLYAGIEHKIGDYAAESIKIITRSASERIVDFACNYVKDN
                     KRKKVTAIHKANIMKMSDGLFLDVFREVASKHGVEYDDLIVDAAAMNLVLNPENYDVM
                     VMPNLYGDILSDLGAGLVGGLGIIPSANIGKDCAIFEAVHGSAPQIAGQNKANPTALI
                     QSSVMMLRYLGEYENAQKIETALEKVFLEGSKLTVDLGGSASTTEFADEVCKYIV"
     gene            29119..29592
                     /locus_tag="KR294_001425"
     CDS             29119..29592
                     /locus_tag="KR294_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBH0239507.1"
                     /translation="MVVSVEVCLIKTLDSNILREVGTLSRAVNSINDIKYKELKLQKG
                     QFTFLTRICENPGINLVELSNMLKVDKATTTKAIQKLIKAGYVDKKQDKFDKRGYNLT
                     PTDKSLEVYELIIEEENRSIEICFDNFTDEEKQVVTKLLEKMSKNVENEWFKVKR"
     gene            29626..30120
                     /locus_tag="KR294_001426"
     CDS             29626..30120
                     /locus_tag="KR294_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH0239508.1"
                     /translation="MIRKANMNDLESIMQIIKSTVEEMKTYNNTQWDENYPLEKDFVS
                     DIKKQDLYIYEVDGEVAGFICLNYEEPEEYLGLNWSSNKKAMVIHRMAVNPNFRKTGI
                     ASKLVDFAEKLAVENNVSYLKSDTYSINSKMNLLLTKCGFIKIGEMSFLGKEKSFYCY
                     DKIL"
     gene            30217..30738
                     /locus_tag="KR294_001427"
     CDS             30217..30738
                     /locus_tag="KR294_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBH0239509.1"
                     /translation="MIGFLKKRRSIRKYKDVEVEKEKLDKILKAALLAPSSKGLRTWE
                     FIVVDDKEKLINLSQCRTKGGGFFLKNAPLAIVIIADKEKNDVWIEDASIAASYIQLQ
                     AHELGLGSCWIQVRNRMHDDNIEADKYIREELKVPSKYSVECIISIGYPDEEKKAYGD
                     SDLDYKKVHFNNF"
     gene            30927..31238
                     /locus_tag="KR294_001428"
     CDS             30927..31238
                     /locus_tag="KR294_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBH0239510.1"
                     /translation="MGIFKTKMDEDWKVNYIKEFNEMRDSYESKLQKKQFEVDSLKSE
                     LDRLRSYKNSLKPKEKQITDDDINNIKSLRRDGLSYKEISNQTSWSKATVSRVLNGLY
                     D"
     gene            31266..31952
                     /locus_tag="KR294_001429"
     CDS             31266..31952
                     /locus_tag="KR294_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBH0239511.1"
                     /translation="MKYSYKKCIIDSILLMFIVQILRMILNYVLLSQFEFTLENFNII
                     NLISFTLVGLSLILFLKDNSLYNKVRNRKITEAFEENKNNILIEKCKLILFVVVLSLA
                     IIVTYCTKGYVLFNVTMMTLSVLIVPIFEELFFREYIWNYLSNFIKSKSKIICITSIL
                     SGIYNIGYIDVIRNYVILYNNSSYTFEVIISKIMIGTVFGIVLGLVKYRFRDVGFCIL
                     LRSLFAIFIR"
     gene            32184..33068
                     /locus_tag="KR294_001430"
     CDS             32184..33068
                     /locus_tag="KR294_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="HBH0239512.1"
                     /translation="MKFVTFCSSNEEKIGVFNSETNSIYEINSLGLSKLYTDMNDFIE
                     NVSTGDLEKIKNNSFENAKCYKLEEVKLCSPIVRPKKDIICLGLNYKDHVNEIPDGVI
                     KNVVMPDYPIYFSKRADKIIGVDDKISLHGDLVEKLDYESELAVIIGKEGINISKEDA
                     YEYIFGYTIVNDISERALQDKHVQWFRGKSLDTHTSMGPCIVHKEEFEHPLKLDISSV
                     VNGEVRQDSNTEYFIFDIPTIINDLSRGMTLKPGDIISTGTPAGVAMGMNPQVYLKHG
                     DIVECKVEGIGVLKNIVD"
     gene            33167..34342
                     /locus_tag="KR294_001431"
     CDS             33167..34342
                     /locus_tag="KR294_001431"
                     /EC_number="2.1.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolecarboxamide
                     formyltransferase"
                     /protein_id="HBH0239513.1"
                     /translation="MARELELKYGCNPNQKPSKIYMKNGELPIEVLNGKPGYINFLDA
                     FNSWQLVKELKEATGLPAATSFKHVSPAGAAVGVPLSDTLKQIYFVDDLELSPLACAY
                     AMARGADRMSSYGDFIALSDVCDKETATIIAREVSDGIIAPGYTDEALEILKGKRKGN
                     YNIVKIDENYTPEPIETKDVYGITFEQGRNEILINEDLLKDIPTDNKIFTDSAKRDLI
                     IALITLKYTQSNSVCYAKDGQVIGVGAGQQSRIHCTRLAGNKADTWYLRQHPKVLNLK
                     FKKDIGRPDRDNTIDVYLSDDYMDVLADGIWQNFFEEKPEPLTGEGKRAWLKTLTGVA
                     LGSDAFFPFGDNIERAKRSGVSFIAQPGGSIRDDNVILTCNKYNIVMAFTKNRLFHH"
     gene            34470..35324
                     /locus_tag="KR294_001432"
     CDS             34470..35324
                     /locus_tag="KR294_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239514.1"
                     /translation="MALNIRNYSLLCNQGTAKFNEDVVGINPFGAWVLDGATGLNGKN
                     LVSTESDARWYVQWWNRYLYKNINKEESLKSIINTGIIEVKKEYELRLNGFKVEKLDL
                     PSSSIVVVKFHENKVEYFLLGDCALFIKNGDSKVIKDRSICKFDNTVFDEMSKLSNLE
                     EMAFDEIRTSVMDTIVSNRLKKNTKEGYWILDFDEEAVENSIYGYIEIKKDFQLMLTS
                     DGFTSACDRYNLIKEEELIRIAEKFGIGYIHNKVRDFEDNDYKAVKVPRFKVKDDSSC
                     LYLDIYND"
     gene            35368..36603
                     /locus_tag="KR294_001433"
     CDS             35368..36603
                     /locus_tag="KR294_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HBH0239515.1"
                     /translation="MKILHIITQKPNSTGSGIYLSGMIKGFEKIGHKQAVIAGIDVND
                     DVNCFPSEVSFYPVKYNCGELNFPVVGMSDSMPYESTRYKDLNIDMINRLKYQFKVNI
                     DKAMNDFKPELIICHHLYLLTAFVREMVKDIKVMSICHGTCLRQLNTIDLEKEYIIAN
                     IRKLDLIFALHENQKYDIIKTFGVSQSKVVVIGSGYNDDIFYNKNYKIKDDKIKIVFA
                     GKICKSKGLIPFIKAISKLKYSKDLIEVNFAGTGSDIESYNEIVKLASKSPFKMNFLG
                     KLEQRDLAELFNRSQIFVLPSFYEGLPVVVLEALSCGTDVITTDILGVKEWIGSEINN
                     SGKIEYVSLPFMEKEGIPKDEELYDFENNLYNAIDSKIQSLLNNSNKKTSVDMSKKTW
                     DGLAYRINEVILMDELCLI"
     gene            36704..37645
                     /locus_tag="KR294_001434"
     CDS             36704..37645
                     /locus_tag="KR294_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp25"
                     /protein_id="HBH0239516.1"
                     /translation="MRISKKVLALGISALLLSVSFPTSINALDKIENIQGVDKYETAG
                     LISDKQDFTTAVLINADSTMVDGIAASGLAGVNNAAILLTNKDDIPEATLQRLNRVTK
                     IYVIGGENSISKDVEKMLLMRRMQVIRIDGVDRVDTSYKIAGEIEKIKNSDKMFLVNG
                     FKDEADAVSVASVAYRDGAPIILTKDIPSAEEDTDLDPWFGVSPVPVYAIGGESTLSD
                     YIVSRYRATRIGGVDRYQTNKNVIEKFYNGAKEFYITSGDDLVYALVASPLAKNAPVV
                     LVSNKSDKSILSGASKVTAIGISDKSIIEQCLDAVKK"
     gene            complement(37864..38217)
                     /locus_tag="KR294_001435"
     CDS             complement(37864..38217)
                     /locus_tag="KR294_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HBH0239517.1"
                     /translation="MDRKRELKQLYKEMKFDTGVFIIKNDITKKIYLGKSNDIKSKFN
                     SLKFQLGAGSCMIKELNNEWKKYGEKAFTFEVLELIKHDDNKTEKDYLEELDILEMVW
                     LEKLKEDNTYEIYSI"
     gene            38513..39424
                     /locus_tag="KR294_001436"
     CDS             38513..39424
                     /locus_tag="KR294_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CGNR zinc finger domain-containing protein"
                     /protein_id="HBH0239518.1"
                     /translation="MNKKIELIGNFASDWIRYSDYEYKITEEDELYIVPTEDAVFTMY
                     NPFDVADDIIVDIIRIGQEALQDISKETKEMKLKKEVLEFVKKYGLLGLIYSSVYNRD
                     IVGEERVLMIEKNYITKENILSTDEYVNMFIPFASDEDVYFKKYRRGIDVSKREESPK
                     FFGKRPLILDLVFSKFYTEQLDWIVSFAKDMCKHFNQICVYKNTSNLLTESVTIMSGG
                     FNPQKIGFSISQLDKPIIAWEFDSLKTAIETIYAFAITSEPSSLNKCKYCGKIYIPTN
                     SKSQYCSPSCRNCSNVKKSRSRAKKDK"
     gene            39684..40118
                     /locus_tag="KR294_001437"
     CDS             39684..40118
                     /locus_tag="KR294_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239519.1"
                     /translation="MISPIILSSINQNLKEIERNELLETNIESGDYGLALSESDVKDI
                     INSRDNTLKGYGRIELDIKVTKQLIENIYTSQYTNVDNYLEAINDMQEIFYYLKNETD
                     DKICDDEIIEILGEFYEKFSGNMDNVRGEADEFAKKFKFGEV"
     gene            40141..>40914
                     /locus_tag="KR294_001438"
     CDS             40141..>40914
                     /locus_tag="KR294_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239520.1"
                     /translation="MLNNLSNININENNLIKNQYSISLLKECLNCKVIDEREVYNIQQ
                     EISLILMDLIKKYTNGQSTSVKTEVAEKLLISIWYAIDAYINKLGDIEKRVVELTAKN
                     VKKVYLGGIEILEEELVRLKDFYKLMMSRKLDTNSIAYNDTLMELSSFFKSYIVKFEA
                     QDVPVSIDYPLALDDMDVKGIYYVKNYIESIDIENRFCNLFKKKDREKLFYDYGVTYK
                     IDCDAILVNLFELIINNCIFSTILGNEVTNLEISKYEYEF"
BASE COUNT        15518 a         4470 c         7413 g        13513 t
ORIGIN      
        1 attttgggta ttgtatactg gaattagagt aattaattta ttttttaaca tacaaatgat
       61 tttatgaaaa aaaacaagac tcaaaaattt ttatattctt tgatagaata aaattgagag
      121 taaatttatt gaattttata aaatttataa ggggtgagtc taagatatgc atgaagataa
      181 aaatgatata tttgaatcaa tagatactga ggattttgat aataaaacag aagaagaatg
      241 tttagagcta gtaagaaaaa atggattgaa tttaatatac ataaaaaatc aaacagaaga
      301 gatatgtcta gaggctgtta gacaaaattg taatgcaata aaatgtgttc agaatcagac
      361 agaaaaaata tgtatagaag cagttaaaca agattggaga atgttagaat ttgtagaaga
      421 gccaacagaa gaaatttgca tgttggctat taaccaagat ggaacagcat taaaatatat
      481 agaaaatcag acagaggagt tatgcttaag agccgttgaa aaaaatggtg cagctttgga
      541 gtatgtaaaa gaacaaacag aagaaatatg tatagaagca gttagaaaca gcgaatttgg
      601 attggcaaga gtgaaaaatc aaacagaaaa aatatgtatg gaagcagtta agcattgtag
      661 ctataatcta aaatgggtag aaaatcaaac agaagaaata tgtatggaag cagtgagaca
      721 aaatgggctt gatttgaaat ttgtaaaaaa tcaaacagaa acaatctgtt taagagcagt
      781 aagacaaaat ggaatggcat tagaatttgt aaaggaacag actgttggta tatgcttaaa
      841 ggcagtaaga caatatggaa tggcattaaa atttgtaaaa gaacaaacag aagaaatttg
      901 tacagaagct ataaaacaag ataaaagagc acttagtttt gtaaaaggag ataaggaaaa
      961 atacaaggct ctatatgata ataatgaacc atttgcaaag agatatgtta gaaatgtaat
     1021 agaaaaagaa aacagagcat tgattaaaaa aggagaagaa aatgcaaaaa tcaaaattgc
     1081 aggaaaactt tatgatagag gcatgtcttt tgaagatata tcagatatag ttgagattga
     1141 aataagcaag ttaaaagtga gtttaggtgt tttttaaggg aaatagttaa taaaaaaata
     1201 atcgactagc tctttgtagg acagcaaaat tagtgatata atttgatgta taataaatta
     1261 tttttattag ataaggggga attaaagttg aagattacag tattatacca aacaagaagt
     1321 ggaaacacag aaagggtcgc taagctgata gaagagggcg ctaaaaaggt ggatggagta
     1381 gatgtaaagc ttatgagact tgataatatt gatttagatt atttaaatga aagtaaagca
     1441 gtaatatttg gaacacctac ttatttagca aatacaactt gggaagtaaa aaaatggttt
     1501 gatgaagatt caaaaaaagt taatttagct ggaaaattag gagctgtttt tgctacatgt
     1561 gattatatat gtggaggtcc agatgttgcg atacttacta tagtaggaca tttgatggtt
     1621 aaagggatgc ttgtgtattc tggaggtggt tctttaggaa agccatttat acatttagga
     1681 catgtacatt caattgaagg tccagagtta caagatgaga aggctataat atttggtgaa
     1741 agaattgcta ctaaggcaaa agaactattt gcttaatttc tatatgcata ataatgatta
     1801 gagtaaattt agggttttaa tggagatttg aagtaaaagt tataaaataa aaaattttcc
     1861 ataaaattac tcaagatgaa ttataatata attataaata aattatatta ttaaaatatt
     1921 taaaatcaaa cgtcaatagc gagggaagtt tatggtatgg catatagaat atgagatttt
     1981 ttctgcaatt atagttattt ttttaatggt atactttttt agaagtaaat ttatacctac
     2041 tttacaaaac aaaatatatt gtgcactttt aatattctca tttttattta taatttcaaa
     2101 tattttaggt tcattttgtc taaataatat agacaaaatt ccaattttta ttactttttt
     2161 attgaatcag atatacttat tgttattgcc aataccagca gcacttgtat cattttatgt
     2221 tatggctatt atttatcaag atataaggta tatgaaaaaa agattattat ttttatctat
     2281 accacttata atttgtataa tcttatctat tacaaatcct tttacgcata ttctatttgg
     2341 attgtcaaaa gaaacaggtt atatacgagg ttgtggatat gttgcaactt ttgcatcttt
     2401 tttcttttat gcaatatatt cagcattttt atcttttaaa tatagaaaag caatgcatga
     2461 atcaaaaata tgggctatta gaggttttct tatagtttca attgtggcaa ttatcttaca
     2521 ggcaattttt ttacagtatc ttcttacagg aactgcatgt gcatgtagtt tacttttgac
     2581 atatctttct atgcagaatc gaggtcttat tattgatgac cttactggtg tactcaatag
     2641 acaatctttt attcaagagc tagatttgaa tatcaatact gaacaatcag gatttattat
     2701 tacaattgcg cttgatgatt ttaagtttat gaatgaaact tttggaacaa aaaatggaga
     2761 tattgcacta aaagaagttg gaaaatattt gattcagata catgatgtaa accatgtata
     2821 tagaataggg ggagatatat tttctattgt tgtcaatagt caattaggta tagaaccaga
     2881 tgatattatc agaaagatag aagaaagatt taaaaagcct tggctagtag aagagataag
     2941 ttttaattta gcaactagta ttgctgttgt ttattaccca gaaaatgcag aaacgacaga
     3001 agatgtaatt gttgctatag atttctctat acatgaagca aaacgttctg agtcaaggcg
     3061 agttgtttat gcagatgcgt ctataagtga aaagataaag aagaaacatg ttattaaaaa
     3121 ttgtttaaaa gaagcattaa aaaatgatgg gtttgaagtg tactaccaac ctatattttc
     3181 taatagcagg ggcaggttta cttcagcaga ggcattactt aggctagaac acaaagagtt
     3241 aggttttata cctcctgatg aatttattcc aattgcagaa caaacaggat tgattaactc
     3301 aattggatta gtagtctttg agaaggtatg tagatttata gctagtgatg agtttgaaga
     3361 tttaaaattg gataatatag ctgtgaatct ttctgtagta caatgtatgc aaaaaaactt
     3421 agctgatgat ttactttatc ttatgaataa atataatgta tcaccaacta aatttaaact
     3481 tgaaattact gagactgtgg ctatgggctc ttttaatata attaaagaaa caatggaaag
     3541 attaattgat ttaggtgtta agtttgcact tgatgatttt ggaattgctt attctggagt
     3601 tactaatatg ctttctttac cattttcagt aattaagtta gataagagtt tgatttggtc
     3661 tatgaatgaa gatagtaggc ataaacttac agttgagacg attatagctc ttataaataa
     3721 attgaatatg aaggctgtag cagaaggtgt tgaaaccatt aagtgtgctg aagatttaat
     3781 agctatggag tgtgaatatt tgcaagggta ttatttttct aaaccagttc cagaagatgt
     3841 ttttaaaaat ttgttgaaag aaaatacttt tacaagttaa caccctttat ttttttaatt
     3901 acaactttgt tcattgacac tgccagcgat atattataaa attaacacaa taataaatat
     3961 taaatttatt atacatatta ttaatattaa ttaatggagt aaagatttat tatatatttt
     4021 atttaattat cctaaagtga gaaaggaaga tgtgacatga ataaaaagaa aatattagtg
     4081 ccaattgatg ggacagaaag aagtatgcat tctttggaat ttataaaagg aatatttaaa
     4141 aaagatgaag ttgaagtaga aataatgaat gtaaaagaac tagtatttat tgatggcata
     4201 tccctggctg aagagataaa aaattctgaa aatttaggaa gaagaatctt ggataaagca
     4261 gcagagataa tgggagagta tgatgttaaa gtacatttta cttttggata tccaggagat
     4321 gagataatta gaaaagcaaa agaagataat gtagatttta tagttatgac aaaatctact
     4381 aaaaaaggtc ttacaagaat gataggttca gtaacagcaa gtgtagttaa acaagcaaaa
     4441 tgtatagtga tgattgtacc ggagtagaat tagaaaggta tttgaaatat gaataaaaag
     4501 atagtagcag tttgtgaaag tgaaagaagt ttaaattctc ttaagacagc tgcaaatgat
     4561 ttaggatttg atttagttta tgaaattcaa gaaaatgata atataaaaaa tgaactttct
     4621 atttatgata tagaagatgc atccatagtg ttatttgtta caagtgattc tatagaaagc
     4681 atagagaaga ttgatagatt tatagataga gaattttatg aagttgatcc aaagtatata
     4741 atagaggatg caaaatctat agtaagtgaa attttaatag acttaaatta atcgtgggtg
     4801 tcgcactaag aatagagcga cgccttttta tatattttac acaagaaata aagaggttgt
     4861 atcaaaatat agataagagt ctttttcatt gttgaaatga tgaaaatata tttgatttca
     4921 tacaaaaaag agtacctcat aactaaaaag ttcactttga gacactccat ttttatatgt
     4981 tagttgcatt taaggtaaaa tagaagttta atcatgttga aataactgaa ttacatcttc
     5041 taaatgattg tacattgatg tataacctaa gtaagagtct ttactatcaa atgcaatcat
     5101 tatcttgtta tggtggctaa tcatatcctt gagagaattt ctatatttaa aaccaaagta
     5161 ttggttagaa gaaactgttt taggtattaa ctcataatat tttataaaaa ttggattatg
     5221 agaagctaaa attatctctt tgtgaaattg caagtcagca tcataacatt cttctatcaa
     5281 accgtgagaa accttatcca attcttctat tgactttagg taagtatatt ttattttttg
     5341 aagttcttta gatgtagcat ttaaaattgc tagtttagta gcttcacttt cgataagttg
     5401 tcttgctctt aaagattcta cataaaattc ttgtatgtta tgatttttat agatttcacc
     5461 atcatcaaat aggtcaactt ttttaaatcc ttcaactata ggacttgaat aaggcacagc
     5521 tctaagtatt ccttccttac agagtatatt tatggcattt cttacaggta ttctacttat
     5581 gttaaatagg tcagcaatct ttctctcact tggtaattta ctattaattt taaaagttcc
     5641 atttagaatg tttaatttaa tataatcaat aattttttca gtggcattta agcttttcat
     5701 aaaaactcct aaacatataa tttttttatg attgtattat atcatagtta agagttaaat
     5761 ctactttttt ataatatgta taagacagga tagaggccaa aatagctata atagccaaga
     5821 taaagtatcc atattgtatt gaagtatatt ccgatatttt accaactatc attggaaata
     5881 cagacattcc tatagcataa attgcttgaa aaaaacccat tgcagtagat ttctgatgtt
     5941 ttggtacatt tttcatagac tcgctagtaa ggtaagaaag gagtatacct gtagatatac
     6001 ctggtagtac ttgtagtaca aatattatat taatattttt tattgttgga actaaaaagc
     6061 aataggctga aactaaaata aaaactaaag gaatccaaaa ttttggccca tacttagtac
     6121 aaaatttagt agaagcaaag ccagaagaag caacagcaca caccatgtaa aatatagaag
     6181 atagacctat gagggtagaa ctagaaccta agtttttaag aatttgagta gtaaatgaca
     6241 ttgttgtaga catttgaata ccctgttgaa ttaatgccat aaaggaaaaa aatacaagtc
     6301 ttttatcctt gcagatagat aaatattttt taattgatat tttttcaggt attttttttg
     6361 aattatgatt ttttatattt aaggctagaa tcgttccaat aactgaagac aatacactca
     6421 tgatacataa ggctgtcatt cctaattttt cataaaataa agtactcata acaaatccaa
     6481 tcaacattcc tagattgttt actaatatta ttgtacttgt agctttttgt tgatgttctg
     6541 tagaaaaaaa gttggtatag tgaaccatgt aagaaatcca agttgatgat gatattccag
     6601 ataaaatgtt agctataaga aaaccattgc ctccaggaga aaagactctt ataagagatg
     6661 ctaaaccagc aaagaaaatt ccagacagta taaatatttt atgtttattt atggaatcag
     6721 caaatactcc aacaggaagc cttaataaac attgtgagat tccatatgca cctattatta
     6781 taccaatcat atttgtagat acattacatg cacttaaata tggattttgg aaaggtatat
     6841 atacatattg tgaaaaccag aaaaatgtaa caatagaaag taaaagtaat ttttgattag
     6901 atattttttt catattatcc tccgtatggt atttttataa tgcaaataat ataccatttg
     6961 gattttttaa tcaagtactt tctctattaa aaaaaattta aatatataat tattatttac
     7021 aaaaaaatta tactttatag ttgaattaag aaaacgctta tgatactata aagttaacaa
     7081 atttgaatat ataacagtag acgtgttact ggtaatgcag gcaagatcga atcaattttt
     7141 atagattatc tatagagtac tatgggtata atctatttat ttggttcgat ttttttgttt
     7201 aattggccat aaaacaaaaa gcctatagtt gaaaatggag gattttttat ggattataaa
     7261 aatatagctc aagaaattct actaaatgta ggaggaaaag agaatgtaaa tgaagtgact
     7321 cattgtatga caagacttag atttaaagtc aaaagcgctt ctaaagtgaa taaggataaa
     7381 ttatctaaaa ctgaaggagt aataactgtt gttgagagta tgggtcaaat acaagttgta
     7441 attggaaata aagtaaaaaa agtatatgat gaggttataa aaattgtacc tcaatcaaat
     7501 aacgtaggta aaaagaatga aagtcaagaa aagcaaggta taattaattc tatattatca
     7561 gcagtagctg gtatatttac acctacaata cctgctatag caggggttgg tatgattaaa
     7621 ggtattttat cagttcttgc tatgtattat atgaataaaa atggagtaga tataaaagaa
     7681 acgcaaagct atattatctt aaatgccctg gctgattcta tattctattt tatgcctatt
     7741 atactaggat atactgcggc taaagtattt aatgcaaata aaataatatc tatggtatta
     7801 ggagctacac tttgttatcc aacttttact gctttgatgg caggtgaaga atctgttaga
     7861 tttttaggat tggcagtaac aaaagctacg tatacatcat ctgttattcc aataattatt
     7921 gctatatggg ctctttcata cgttgaaaaa gtattagaaa agtatatacc tgaggtaatt
     7981 aaaataataa tggttccaac tttatcattg gtagtaatgt tacctgcaac attattttta
     8041 tttggaccaa tcggaattta tataggaaat gtcataaact tttcttataa gtatatttat
     8101 gaattaagcc cagcattgtg tggagcattt gtaggtgggt tatggtgtgt gttggttata
     8161 tttggtgctc atagagcatt attaccaata ggtataagtg atgttgctca aacaggaaga
     8221 cagaatttat tggcatttgc aggagctgca aacttttcac aagcaggggc tgctctagga
     8281 gtattcttta aaactaaaaa tcaaggacta aaaacaattt ctatgtctgc aactataaca
     8341 gctttatttg gtataactga acctgcaata tacggtgcca atcttagatt aaaaaagcct
     8401 atggtatgtg ccgtaatatg tggtgcattt ggaggtgcga taatgggaat gggtggagct
     8461 tatggtaatg catttgcaaa ccaaggtgtt ttaactatac ctgtatatgc tgaagcaggt
     8521 gcattaggtt tcttaagtta tctaggtggt tgtgctatag cattttttgg ttcagctatt
     8581 tcaacttatc tagttggatt tgaagatttg gaagagtctt ctaataagga aaattcatct
     8641 ataaaagtag aaacgaagga tggtgttatt gatataactt cacctgtaga gggcgaatgt
     8701 atagaattgt cagaagtaaa ggatgatgta tttgcttcaa aagctatggg agaaggtata
     8761 gctgtgttac ctacaaaagg agtaataaca gcccctactg attgtgaagt agcttcttta
     8821 tttccaacat tacatgcaat aggattaaaa ttagataatg gagcagaaat gttaatacat
     8881 gttggaatca atacagtaga gttaaatggt aaatacttta ccaaacatgt taatcaagga
     8941 gatttagtga aaaaaggtga taaacttata tcgtttgata tagataaaat aaaaaaggtt
     9001 ggttatgatg taactacgcc agttatagta aacaatacat ttgattttgg gcaagtagtt
     9061 tcttgtaaat ctagttatgt ttcaaccaat gataatataa tttcattagt attagctggt
     9121 aattaagtta atttgactag agataagtaa attgatttaa aaggaaataa gtaaatcaac
     9181 aattaaatac atctaaaagt aagtttattg caatgaattg ttaaagaaaa taattaatat
     9241 ggagtaaatc tattgcaatg aagtaacaaa gaaaataatt aatatagagt aagtttattg
     9301 taatgaattg ttaaagaaaa taattaatat agggtaaatc tatttcaatg aaataacaaa
     9361 gaaaagagtt aatatagagt gaacttattg caatgaatca acaaagaaaa taattaataa
     9421 aaaggagaaa tatttatgaa tacaggattt ccaaaagact ttttatgggg agcatcatct
     9481 tctgcatttc aagtggaagg agcttgggat aaagacaata aaggaaaaac cgtagccgac
     9541 tataattctt ttaaaaagtc tcatttacag gcagatacta aagtcgcatc agacttttac
     9601 cataattatg aagaagatat tgaattaatg aaagaattag ggatgaaaac atatcgtttt
     9661 tcaatttcat gggcaaggat aataccagat ggtgaaggag agataaacca gaaaggttta
     9721 gacttttata ataagataat agacaaacta atagagtgtg atattgagcc attcgtgact
     9781 ttataccatt ttgaccttcc atttaaatta gtagagaaat ataatggttg ggaaagtaga
     9841 gaaactgtct atgcttttga aagatttgct aaaatatgct ttaagcattt tggagatagg
     9901 gtaaagtatt ggcaacctca taatgaacag aatttaattg ttagagtgga ggagagaatt
     9961 aatatatatg atgaaacaga ttcatggaag atagataaaa tgcgtgctca gatggattat
    10021 aatctttgct tagcacatgc attagcagtc aatgcatgtc atgagatgat aaaagaaagt
    10081 aaaattggag cagcagtatc atcatctgta acatatcctc ttacttctaa gccagaagat
    10141 atatatgcag ctagaatgaa tgataatttt aaagtgtact atatgcttga tatgcatcat
    10201 tatggagaat atccagggta ttatatgaag tatcttgaaa aaagaaatat agttcctcac
    10261 atggaagatg gggataaaga gatacttaaa aaagctaaaa tggattttat agctgtaaat
    10321 tattatagga caaattgtgc agaagcttta cctgaagatt cacaacatcc atttggatta
    10381 agagaaggaa ctgttgattt tagtatgtat ggactattta aaatgtcaat gaatcctaac
    10441 ttagaggctt ctgagtatgg agcagcaata gacccatcag gtcttagagt tgccttaaat
    10501 gaatattggc aaagatatca cttacctgtt ataataacag aaaatggtct aggagctaaa
    10561 gatatattag aagatggaaa aattcatgat gactatcgta tagactattt aagaagtcat
    10621 ataaatgcat gtaaactagc tattgaagat ggtgtagaga tgattggata ttgtccatgg
    10681 tcatttacag accttttaag ttcttctcaa ggttttaata agcgttatgg acttgtttat
    10741 ataaatagaa ctgaccatga aattttagat ttaaaaagaa tcaagaaaga tagtttttac
    10801 tggtataaag aagttataga gaacaatgga atagtaaaat aaacataaat atatattgag
    10861 ggttttagta tgtacattac aaaggtatta aataattcgt tgctacttgc aaaggatgat
    10921 aatgatgaag aaataatatt gatggggaaa ggcattggcc ataattataa ggccgggtct
    10981 gagttaaatg aaaaagatat agaaaagatt tttgttcttc atgatgaaaa tataaaaaag
    11041 agtattatac aattggcaac agaaatagat gcagaatatt ttggtatagc tcaaatgata
    11101 attgcatatg gaatagaaaa atataactta aaacttatga accatatata tttggcctta
    11161 actgaccaca ttgcctttgc agtgagacgt tttaaagaag gtataatgat tgaaaatcac
    11221 tatttgttcg aaatcaagga atttaatcca aaagagtatg atataggaaa atatgctatt
    11281 actgttttta aggaggttct tggtttagac ctaccagaag aagagattgg taatatagca
    11341 ggccatttta taaatgcaca acaagataat ccttatagtg atagaaataa gagaagtgct
    11401 aaaattgtaa atgctatttt gcaaatagtt cattatcact tttctattgt atataataaa
    11461 gagtcatttt attataggag atttgtaatg catctaaagg ccttttcaca aagatttctg
    11521 gctaatgaac catcaagaga aaaaatagat tttatatatg agcaagttca aaaaaattgt
    11581 aaggaagagt atgaatgtgt gaaaaaggta ggagcttata tgtataagga atactccaga
    11641 gaattaccaa gacaagagga gttatatttg atgattcata ttcataagat tttaggagaa
    11701 ttatgcgaaa atagttagaa tatcttaata tgctagtaat attataaaaa attaaaaatt
    11761 aactgcactt taaatatgaa taattgcatt acttaagggg gttgtcttaa aattgatttt
    11821 tttaattaaa tttgaagctc aactcctttt ttaaaccttt atatcattac aactttaatg
    11881 tttatacgcc tgtacttcag atgtatatct actttttaca tttctcaaca tgcaaatcta
    11941 ccattctgta tatagtaaat gtattatcat gtttgtttta ttcaagcaca cttataatac
    12001 gcttgatttt ttcacaatga tgaaatatac taatgggtgt tataggtata agaatcgcat
    12061 tacacttgaa gaagtaagtg ataaatgaga tataaatcct catatgataa actactattt
    12121 cattgaggaa catattctaa gtgatgtcaa gatactacaa tatgactaaa ttcctagtga
    12181 taaaaaagtc tacgaatgag tgtagaaagg ggaactaaga tgaataaagt tttaattata
    12241 gatgatgata aagatctttg tattttgtta aaaaagagta tttcaattga acagattgaa
    12301 gcaaactatt gccattctgg gagagatgga ctggttgaac tttcaaaaca agattatcag
    12361 ttagtagttc tagatgtgat gatgccaggt atggatggtt ttgaaactat ggaacaaata
    12421 cgaaaatata gcagtattcc tatcttaatg ctgacatcaa aaagtgataa ttacagcaaa
    12481 gtgcatggat tgcgagctgg tgcagatgac tatctaacca aaccatttga aattacagaa
    12541 tttactgctc gtgtactgtc tttaatccga cgttacaccc gttttaatcc aaaaaatgag
    12601 gagccacagc aactttcttt caaaggtttg ttgattgacc ttgaccagca tacagttact
    12661 accaatggcg aacctatgtt gcttccaccc aaggaatttg gtgtacttct ttactgtgca
    12721 aggcatcagg gtaagatttt gacaaaacag cagatttatg aagccgtgtg gggtgagcca
    12781 tatgtatatg atgacagcaa tatcatggct attatcagtc gcctaagaaa aaaaattgaa
    12841 ctagacccat catctcccat ctatttgcaa acaataaaag gaattgggta tcaattcaac
    12901 acggaggtat gaaaatggat gaacaaacga taattctttt cttactcttg ctgtcgattg
    12961 gtctactttt tctttccata tttgcttttt ccaagcttgg gcatattcac aaacgcttaa
    13021 aagatataga ggagatactc gctgatgtac aaattggaga cgaaaatcgt aaaatactaa
    13081 ttaagccatg tgatgttatg gctccattgg tttatcagct taatgagatt gtctacgatt
    13141 atgaaaataa gttactttct ctgaaaaagt cggataaagc tagcaaacaa cttatgacaa
    13201 gtttatctca tgatgttcgt acaccattaa caactctgat tggttatctg gatgctgtac
    13261 acagtggtat agttatcgaa caagagcggg aggaatacct tgaaatcgct aggcgtagag
    13321 cctacgacct caaggattac attgatgttc tttttgactg gtttcggttg aactctgatg
    13381 aatttacgct gtcaatagaa tctgtggaaa ttgcagagtt gtcacgcaat attttgaaag
    13441 actggattcc tatattccat gaaaagaaac tgaattttga aattgatatt ccagaaaatc
    13501 gactaatggt aaacctcgac ccagatggat attcccgtgt ggtcaataat ctggttcaaa
    13561 atgttcttgc tcacagtaag gctcggcaaa tcaagattac catgagtgag gattccagaa
    13621 tggtattact ccgtgttgag gatgatggtg ttgggattgc cagagaaaat ttaccacata
    13681 tttttgagcg actgtataag tgtgataaag gacgttcaga aaaaggaagt ggtcttggtc
    13741 tatctattgt cagtcaaatg gtggagcgaa tgggtggtca ggtttccgta gaaagtgaga
    13801 ttggaaagta taccgtattt acagtgagct taccattaat ataaaattgt ttttccccca
    13861 tgtgacatgt atacacaggg ggattttttg taagttataa agttgcaagg ttaatacaag
    13921 gttgttgcaa ggttaatgta agattgaggt ggtatgataa ctttaataaa caaaggaggc
    13981 ttttattatt tatgaataat ttaattattg aaacaaaaaa tctcactaag caatatggtg
    14041 ctcaaaagag cgtttctaat ttgaatattc acgttcagaa aggtcgcatt tacggattgc
    14101 taggaagaaa cggtgcgggt aagacgacaa ctatgaaaat gttattgggc ctaacaaaac
    14161 caactactgg agaaattaaa atatttggtc aggacattca caataacgag aagaagcttc
    14221 ttcctcgaat tggatgtttg attgaatcac cagggtttta tcctaatctg acaggaacag
    14281 aaaatctcaa aatctttgca aggcttagag gaataccaaa aaaaaatgca gtagaatcag
    14341 cactggatgt agtcggtttg ccaaacaatg acaaaaagtt attttctcaa tactctcttg
    14401 gtatgaaaca gaggttggcg attgctcttg ccattatgca tgacccacaa ctgttgattt
    14461 tggacgagcc tatcaatgga cttgatccta ttggtattgc agaagtaaga acgtttattc
    14521 gtgatctctg cacagaacga ggtaaaacta ttttgatttc cagtcacatt ctttctgaaa
    14581 ttgccttgtt ggcagatgac attggcatta ttgaccatgg tattttgttg gaggaagaaa
    14641 gtcttgccca attagaagaa aaaaacagta aatacataca ttttgctgta tctgatgcag
    14701 cacaggcagc aaggcttctg gaaacccaac ttaacctgaa aaatttcaaa gtagcagata
    14761 attacaatat tatgctatat gatacagatg tttctgttgc agaaataaat cgtgctttca
    14821 ttctaaacaa cattgaggta tcagaatctc atttatgcga agatactctt gaagattact
    14881 tcaagaaagt aacagggggt gaaggaattg cttgatataa tttcatgtga attttcaaaa
    14941 ctcaagcggt taaaatttat actgatttct attttaggtg cttgcttatt tccaattccc
    15001 gcaacaattt tgattgcaaa ggacaacttg ccctttgagc aattgttcaa attagttgtc
    15061 aattttggat atttcttgct attaccaatt gtattaagta ttgttgctag ccaactattt
    15121 tttatagaaa gagataatga tgtattaaaa aatcttgcaa cagtgccagt gccaaaagga
    15181 aaactggctc tggcaaaatt ggctgtgttg ctgtttatat cattgttcta ctctgttgca
    15241 gggttaggag ctactatcat tggaggtttc attgttggaa tagtagaggg ggttgctgta
    15301 aaattaggaa tgagcattgc ttttggaatt atgttttttg ttactgtact tcctgttgtg
    15361 gtactcattg tatatttcaa tcgcagctat attttttcta ttatactttc ttttgtatat
    15421 gctattttca attttagtat atccttaaat attatcaatt ttgaaccaaa taacccacta
    15481 ttaagcgtat tacctgctcc tgttataatg cgttggtgga tggcattttg gggagatccc
    15541 actggcgaat acacggtact tagacagcca tatttgctct caactcctgc ttgtgtaggt
    15601 attttatgtt tgataaccat tatagcagtc ctgctgattt gtatgatata caaaaagcag
    15661 gagaattagg aggtatctat gcttgatata attactacag aatttcaaaa aataaaaaga
    15721 tataatattc tatggattgg tgttgttgct gttctgtttt cagcactatt ggcagttttt
    15781 caggttgtaa gttcacacgg cagtgaccct ctaacgtatg agagctttgc aaacggagtt
    15841 atctggaata atttcagtct tagttttcca tttgggatta cacttattgg aggatatctt
    15901 attaaccgtg aatatacaga ccaaacctta aaaaacatcc taactgttcc tatttcatta
    15961 cgcaaattgc tagtgggaaa attaattgcg gttggaggaa ttactgtatt gttaagtctt
    16021 ttcagcttct tatgcacatt tattttgggg ttgttatttt gcaatatcaa tatatctgtt
    16081 atactcgttg taaaatcctt agttcagatt ttgtctgtta atctgtattg ttatgttgct
    16141 gttttgccga ttattgctta ttttggtcgt aaacaaaatg catttctgac gggtgtaggg
    16201 attgcatttg tatacggttt ttgtggtgtg tttgttgctg gaagaaatct gacagacttt
    16261 tatccaatca cagcaggtct tggtctagtt ggatacaaca atggtgctgg tactgtttat
    16321 cagccactta tcggtgctat gactttgatt gtaattctaa tcttgacaac tattctactt
    16381 gtatttacac ctaattatga taaagttatg accatatcta agaaaaaagg gataaagcat
    16441 aaaaagtatt ctcataaata acataaatat tgtttctatt atttaagttg ctagacagtg
    16501 aaaagaaaaa atctgtcgta cagtggctat atgctcatgt attcaagaag ctacagtttt
    16561 gatttttcat aactgtagct tctttttgta tttattaaat cacgactatc ataatacttg
    16621 caataggtat agtaacaaga gagagtactg tcatatgtgt tttatatatt acattaagta
    16681 tattctaaaa tatatgtttt aaataatata tttgaaaata ggaatattta aataaaaaaa
    16741 ataatattat atatagttga caaaaattgg caaatgatat actatataaa tatagaaata
    16801 gtaatcatta ctattattaa aaagggagga attaattatg aacttaaaag gaactaaaac
    16861 agaaaagaat ttaatggcag gatttgcagg agagtcagaa gcaagaaata aatatacata
    16921 ctacgcttca aaagcaagaa aagaaggtta taatcaaata gctgctatat ttgaagaaac
    16981 tgctaacaat gaaaaggaac atgctaaatt atggtttaaa cttttacatg atggtatgcc
    17041 ttcaacagag gaaaatttaa aggatgcagc agcaggtgaa aactatgaat ggactgatat
    17101 gtatgcaaaa tttgctaaag aagctagaga agaaggattt gacaagatag cttatttatt
    17161 tgaagctgtt ggaaaaatag agaaagagca tgaagaaaga tacttaaagc ttttagaaaa
    17221 cttaaatgaa ggaaaaatat ttaaaagaga tgaagaagtt gtttggcaat gtcaaaactg
    17281 tggtcatgtg tatgtaggta ctgaagcacc agaaaaatgc ccagtatgtg accatccaaa
    17341 agcatatttt aatataaaag ctgaaaatta ttaaaaatta tcattattaa aaaggaatgt
    17401 taactatgaa attttctaaa caacgagaac tgattttaaa tgaaatatta aataatccgg
    17461 ttcatcctac tgcggattac ctatatgaaa acttaaaaaa agataatccg aatttaagct
    17521 taggaactgt gtatagaaat ttagctcagc taacggaaca tggctttata agaaaggtta
    17581 gtattccagg gtatccagat agatttgatg gtcgaataga taatcactat catatcatat
    17641 gtgaagtatg tggagaggta tacgatttag aatccgaagt tcttaataat ttacaagaat
    17701 taatatctga ggagacagac ataaaaataa catcttataa cataagtttt aaagggattt
    17761 gtaataattg taaaaggtgt agccaagtag gttagttttc aaattctaaa aataattaat
    17821 gaggtgagtt tatgtgtagt gaacaaaaat tttttatatg tgagacttgt ggaaaccttg
    17881 taggaatgat acaaagtggt ggtgtaccta ttttctgttg tggaaaacct atgaaggaac
    17941 ttgttcctaa tacaacagat gcagcagttg aaaaacatgt acctgtaatt gaagtggatg
    18001 gaaataatgt tactgttaaa gtaagtagca caactcatcc aatgactaaa gaacatcata
    18061 tagcatgggt gtatcttatg actgaacaag gtggtcaacg caaatgtcta gcagtagatg
    18121 gagaacctgt agttaaattt gctttgaatg atgatgataa agtgatttct gcctatgctt
    18181 actgtaattt acatggatta tggaaggctg aactgtaata tttaaataaa ttgagtcaaa
    18241 aaggaggcta taaatgtatt ttcatacaaa tagcctccta taaatttata taaattcaag
    18301 ttttaatttt gtttaatgtc aatataatat aaggagaaaa taatatgtca atttataaat
    18361 gtagtgtttg tggatatatt tatgatgaat ctaagaatga taaaacatgg gatgaattaa
    18421 gtgaagattg ggaatgccct gtatgtacaa aaggtcgtag ttattttgga aagataagta
    18481 ctgtttacta tgaagaagat gaaaagatag cagaagacat agttgaagat gaatctaaat
    18541 taaatactga aaaagaggga gatttaaatt acttaagtac atatttaaga agagatgatg
    18601 aagttgagaa acatatggat ataattcacg aaatggctgt tacaggaaaa tctataatag
    18661 aacctatgag aactaaacta ccagtaattt cttgggatga tattttaatt atgggtgctc
    18721 aattaaatcc attaccttta aatgagcatg atgaagtaaa tacaacaaca ataataggaa
    18781 aaaaagcaaa gaaacctatg attatagaaa atccagttta tatttcccac atgtcatttg
    18841 gagctttgtc taaagaacta aaaatagctt tagcaaaggg tgcagcccaa aataagacag
    18901 ctatgtgtag tggtgaagga ggtatattac cagaagagaa ggaagcttca tacaagtata
    18961 tttttgagta tgtaccaaat aaatatagtg taactgaaga aaatcttaaa aattctgatg
    19021 ctatagagat aaaaattggt caaggaacaa aacctggtat gggaggtcat cttcctggcg
    19081 aaaaagtaac tgaagaaata gcaaaagtaa gaaataagcc tgtaggtcaa gatgtaataa
    19141 gtccatcttg ttttgaggaa atacaatcca aagaggattt aaagaaactt gtagatgaac
    19201 ttagagaagt ttcagaaggg cgtccaatag gtgttaaaat ttcagcaggt catattgaaa
    19261 aagatatgga atttatagct tatgctaaac ctgattttgt aactattgat ggtcgtggtg
    19321 gagctactgg agcaagtcca aagttgctta aagatgcaac ttcaattcca acaatatttg
    19381 ctctttatcg tgctagaaaa tacatagata cacatggatt agatatagat ttggttataa
    19441 caggtgggct tcgtatatct actgattttg ctaaggcaat tgctatgggg gctgatgcag
    19501 ttgctattgc aagttctgct cttatggcag cggcgtgtca acaatatcgt atatgtggtt
    19561 ctggtaagtg tcctgtagga gtagctactc aggatgagga attgagaaaa agattacata
    19621 tagaaaatag tgctaataga gtggcaaact ttttaaatgt aagtttagaa gaacttaaga
    19681 cttttgctag aatttctggt cataaagata tacatgattt aagtgttgat gatttatata
    19741 ctgttaactc tgaaatatca aattatacaa acatacagca tgtatagatt gaagtttgaa
    19801 actattagat tttagacagc tataaaagta aatgataaat atattttata aaagagagtg
    19861 tcttaaaatg aactttttag ttcataagtc actctttttt gtatgaagcc aaatatattt
    19921 atcattttag caatgaaaaa gaatcttatc tctttatttt gagatagact ccttctattt
    19981 atgaaaatta aagatattaa attgtaaaat attctgtgat gtcgtactat taaactaaag
    20041 attctgtact ttaaagtaaa taaaaattta aggagtgatt attatggaaa gattgaagat
    20101 acaagtttta gtcgacaata atacttatat tgatagatac tttgttggag aaccagcagt
    20161 aagctattat attgagattg atggaaatag gattttgttt gactcagggt attcagatgt
    20221 attcatatca aacgctgaaa aattaaatat agatttagga aatttaactc atgttgtttt
    20281 ttctcatggg cataatgacc atacaagagg tatccagttt ttagaaaata ggtatgattt
    20341 atctacagtt gaacttattt cacatcctaa ctgttttata cctagaaaac atggagagaa
    20401 aagcatagga gctccatttt ctgctgagga aattaaaaat atttttatgt ataatcctaa
    20461 ggataagcca tttaatctaa gcaagaattg tgtgttttta ggtgaaatac cttctataaa
    20521 tgattttgaa aaaagagcta aaattggtaa atgtaaaata ggagatttgt gggaagatga
    20581 ttatgtttta gatgattctg ctatagtttg taaaactgat aaaggtattt ttattgttac
    20641 aggatgttct catagtggaa tttgtaatat agtagagtat gctaaaaagg tatgtggaga
    20701 tgatagagtt attggtatac taggtggttt tcatcttttt gaattgaata ataggttaga
    20761 tagtacaata caatatttgg ataaagaaga aataagaatg ttgtaccctt gtcactgtgt
    20821 ttcttttaag gtaaaagcga agatgaatga aatattgaat ataaatgaag ttggagtagg
    20881 gctgaccata agtatatagt atttgaaagt atataagatt taagttgaag gttaaaaaga
    20941 tattttctat agaaaatatc ttttttgtta cgtttatttt aagagaaatc aatatacttt
    21001 tatatgaaat attgtaaaaa aatttatttt taatgagaat atattttcat taataaacaa
    21061 ttttattatg tattaataat gttagaataa atataaataa atcaaagtta cttacattac
    21121 agtatatttt ttcacaaaat atattgattt attcttttaa agtttgataa ttccaatgaa
    21181 tgtaataaaa gaaggaattt tatactatac tattattatt ataaaataat aaagaaaaaa
    21241 ttatataata ataaagaaaa aatgtataat atttaacatt aaaaaagata tttcataaaa
    21301 ttaaaaaaca aagtgaattt gaatactatt taaaaaataa aataaatata taaaaaatat
    21361 ttaatataaa ggtagaaata agttgaaaat gtaaagtcat tggaaaaata tagttgaatt
    21421 taatgagcaa aaatgttatt gttttatcaa taaagtgtta aaataaaaac ttttaatatc
    21481 attttaggga ggatgatttc atgcaaaaaa gtgtaaagaa agcaaaagta acgggctcta
    21541 tgttagccat ttttggtgtt gcaagcgttc tttttagttc acatgcagga ggaggatttg
    21601 ctacagggaa tcaagaaact cagtactatg tgcagtatgg atggacagca ccacttatgg
    21661 caattttagc aatgattata cttactgcta ccatgagaga agttatcata atgtataata
    21721 ataacaattg taggaattat aaggatttat tttgtgagct ttggagacca tatccaaaac
    21781 ttgaaataat atgggagata tattactatc taatggtttt aatagctgta agtgctgtta
    21841 tagcaggtgc agcagcagta tttcaaagta taggagtaaa ttattttgta gctgtattta
    21901 ttattggagt tgtacttctt gtctttacta tatttggtgc tatgcttgta tctaaagcag
    21961 ctacagcaat gacaatagct attctagtat gtactcttac tatttttatt gttggtataa
    22021 aagctaaagt accagaaata actgaaatat tatcaaatag aacgagtttc acacctggct
    22081 atatcaagcc aatacttaat acttttattt atgcaggttt tcaatcggtt gttataccta
    22141 cacttgcagg atgttcaaga ccacttctta agaactcaaa agaagctact aaggcaatga
    22201 taatttcatt tgttatgaat gcaattgcat taggacttgc tgtaactatg ctaatgggat
    22261 ggtatagaga aattattgct gctgggcaaa caacactccc tactctttat gttgcaggtc
    22321 aatctggaaa tcatactata tacataattt ataatgttgc attattcctt tgtttaatgt
    22381 ctacaggagt aactactata tttggtcttg taaatagatt tgaagaccat aaagcacttt
    22441 ctttcctttc ttcaagaatg aaaagaaggg tatttacagc ttgtgcaata atggtagtgt
    22501 caatgcttat atcacttaca ggattaagta atattgttaa atatggatat ggatattgtg
    22561 gttatcttgg tctattcact atagtaattc cattccttac actaggacat tataagaata
    22621 agaagtttgc aaaggaaaat ccagaagcta aatggccagc ggaattaaat gaaaatgtaa
    22681 attagatgta gtagcaaaaa atattgctaa agagaatact atagataaga atactataga
    22741 taatatatct gcatgtttat taagattatt tgcaaaatct aatattaaac aactataaac
    22801 aagcaatata aaactaagaa taaaagataa aaagagggtg tctcaaaatg gacttttagt
    22861 ttataaggca ctctttttta tatgaagtca aatatatttt cattattttg acaataaaag
    22921 agactaatcc tactttggat agcctctttt ttctttaata taaaatagta taacagcaaa
    22981 gtatagattg atacatgttt tctgtagctt tctatatatt acagtgtttg tgtggcattg
    23041 gtattttaag caatctataa attataattc tataattctt ctactaattt tagattctat
    23101 agccgtctct atttcactta acattcgttc atttttaggg tcaataaaag cacatgtata
    23161 gccttcttca ccagctctac cagttctacc aatacggtgg atgtagtctt ctggtgtttc
    23221 tggtaaatcg taattatata tatgacttac tccagatata tcaagaccac gagaagctac
    23281 atctgtagct attaagtatt gtatatctaa atttctaaat gatttcatta ttctttctcg
    23341 ttttgattga gcaatatcac tatgaagttt ttgacaatta tatcctctta tagcaagagc
    23401 ttcttcaaga ttgtcaaccc ttctcttagt tctacaaaat attattgcca taaaaggatt
    23461 atcttcatct agtaccttac ataaggcatc taattttttt ctatctgtag tttctactac
    23521 ttcttgtttt atattattaa gagtgatttc ttctttttga atagaaacta caacaggatt
    23581 ttttgtgtat ctataagcta atttttttac ttgagaattt atagttgcag aaaagcatag
    23641 tgtttgcttt ttgtttgaag tctcttttaa aatagcttcc acttcatttt taaatcccat
    23701 aagcaacatt tggtctgctt catctaaaac aaaagtcttt aacttactaa ggtctattgt
    23761 ttttctattt agatggtcta aaagcctacc tggtgtagct ataatcatat gaatatttcc
    23821 ttttagtttc tttatttgag aaccaatatc ttttcctcca tatgctgcaa gaatacttac
    23881 atctttagat tctttaagtt tcatagcttc ttctgttatt tgaatagcta gttctcttgt
    23941 aggagaaagt ataagtactt gtatatcatt tatatctaat gatatatttt caaatatcgg
    24001 aagtaaaaaa gctagtgttt ttcctgttcc agtttgagct tctgctatta catcttttcc
    24061 ttcttttatt agtttaatac tttctttttg tataggtgta ggtgttgtta ttcctgattt
    24121 ttttagaata tttattgtat tttcactaat ccctaagctt ttgaaatcca ttgttatctt
    24181 acctttcatg aaaaattttc ttttttatta accaattaat aatatcatat ttataagtat
    24241 ttttagtaaa ttttttaatt attatttata tagcttaaaa atatattaag atactttaaa
    24301 atggaatgta acttaaatta aattttagta ggaattttat aggtttattt ttaaaggttt
    24361 tttgaaaata aatctattta aaaattaaat taaaatgcaa gaaaaacata ataactttca
    24421 tttttaagaa gttttcacaa aaaagaaaaa atatagtgca ataaatgata caaagtaata
    24481 taatagatta caagatatga aaagctaaaa aaataaattg caaatgaaat taaaatgaat
    24541 aaaaaataaa aaaataatca taagttagag gtatcaatga aaaataagac ttaatgtttt
    24601 aaaattaaaa gtatactaag gggggcatta atatgtgcgt tatatcaaaa gatagagcaa
    24661 aggaaataaa aatagtagat actactttaa gagatggaga gcaaacagct ggggttgtat
    24721 ttgcaaatag agaaaaaata atgattgctg aaatgttaag tgacctaggt gttgaccaaa
    24781 ttgaagttgg tatacctact atgggtggag atgaaaaaaa tgtaataaag cacatatgta
    24841 gtagaaattt aaaatcagat ataatggctt ggaatagagc agtaataaaa gatgttgaag
    24901 aatctatttc ttgtggtgtt gatgcagtag ctatatcaat atcagtatct gacattcata
    24961 tagaaaataa attgagaact tctagaggct gggttttaga aaatatggct aaaacagttg
    25021 aatttgcaaa gaaaaatgga ttatatgttt cagtaaatgg agaagatgct tcaagagcag
    25081 atatagactt cttaactgaa tttataaatg ttggaaaaca agcaggggca gatagattta
    25141 gatactgtga tacagtagga gttatgaatc ctttttctat aaagaatgca atagaaactc
    25201 tttatgaaag aactaatttt gatatagaaa tgcatacaca taatgacttt gggatggcaa
    25261 ctgcaaatgc acttgcagga atagcagcag gagcaaatta tgttggtgtt acagtaaatg
    25321 gattaggtga aagagcagga aatgcagcat tagaagaagt tttaatggca cttaagtgtg
    25381 tttataaatg tgatttaaat aatatagata ctagaaaatt tagaggaata tgtgagtatg
    25441 tagcacaggc atcaggaaga atacttccta catggaaacc agtagttggg gataatatgt
    25501 ttatacatga atctggtata catgcagatg gagctttaaa agacccacat aactatgaac
    25561 catttgaccc aagtgaagta aatcttgaaa gaaaaatagt aataggtaaa cattcaggaa
    25621 gagctgcagt tgtaaataag ttgagtgaat atgaaatgta tatttctcca gaaaacgcta
    25681 ccaagctatt aaatgctata agagctacat ctataagatt aaaaagaagt ttaatggata
    25741 aagaaattct tcaattatat tgtgatatac tagcacatga gaaaggcaca acagaagaag
    25801 aagcagttag aggttcatat atttaagata taattgttta ggaggaaaat atgggagata
    25861 atatagttta taaaataatt aaaaaacata tagtagatgg agaagctgtt gctggaagtt
    25921 caattggtat aaaaatagac caaactttaa cacaagattc tactggaaca atgacatatc
    25981 ttcaactaga agctatggga atagataaag taaagactaa aagaagtgtg gcatttgtag
    26041 accataatat gttacaacaa ggatttgaaa atgcagacga ccataagtat atacaaacag
    26101 tggcagataa atatggagtt tatttctcta agccaggaaa tggtatttgt catcaagtat
    26161 ttttagaaag attttcaaca ccaggagata cacttttagg ttctgatagc cacacaccta
    26221 ctgctggagg tgtgggcatg atggctattg gagctggtgg attagatgtt gctttagcca
    26281 tggcaggagg agcatactat ataaaagcac caaaagtctg taaggtgaat ctagttggaa
    26341 aattaaataa tatggtatca tcaaaagata taatattaga agtgttaaga aaacaaactg
    26401 taaaaggtgg agtaggtaaa gtttatgaat atggtggaga aggtgtcaaa agcctatctg
    26461 ttccacaaag agctacaata acaaatatgg gggctgaact tggagcaact acttcaatct
    26521 tcccaagtga tgaaaaaaca ctagaatttt ttaagagtca aggaagagaa gaggcatgga
    26581 tagagctaaa accagatgca gatgcagttt atgatgaaga gattactata aacttggatg
    26641 aattaaaacc attagctgca aaacctcata gcccagacaa tgtagatgaa gttgaaaata
    26701 taggcaagat taaaatagac caagtggcaa taggaagttg tacaaattct tcttatgaag
    26761 acttaatgaa agtagcacaa atcctgaaag gaaataaagt acataaggat gtgagtttgg
    26821 taatagcacc aggttcaaga caagttatgg agatgattgc tagaaatggg gctttggcag
    26881 atataataag tgctggagct agaatactag aaaattcttg tggtccatgt attggtatgg
    26941 gtcaatctcc aggtactgac tctgtgtctt taagaacttt caatagaaat ttctatggta
    27001 gaagtgggac tttgtcagca caagtatatt tagtaagtcc agaagtggca gcagtaagtg
    27061 caatcaaggg agtgcttaca gacccaagag aatttgatat taaatttaca aatttagatg
    27121 taaatgaatt tttgatagat gatagcatga taattaaacc tgctgatgta ggaagtgatg
    27181 tagaagtagt tagaggacct aatataaaac ctttccctct taatacagag ctaagtcagt
    27241 ctataggtgg aaaagttata ttaaagacag aagataatat aactactgac catataatgc
    27301 catcaaatgc taagttactt ccttttagaa gtaatatacc gtatcttgca aactattgtt
    27361 tcaatactgt agatacagaa tttcctcaga gagcaaaaga caataatggt ggatttatag
    27421 ttggtggaga taattatggt caaggttcaa gtagagaaca tgcagcttta gcaccattat
    27481 atctaggtgt taaaggggta atagttaaga gctttgcaag aatccacaag gctaacttga
    27541 taaatagtgg tataattcca atggagtttt gtgatgagaa agattatgaa aatatatctc
    27601 ttttagataa tctggagata ccaaatattt tagacaatct aggtagtgga attttagaag
    27661 ttaagaatac aactaaagga acttctttta aggtcaaagt agaattgtca gcaaaagaag
    27721 ttgatgtatt aaaagctggt ggaaaattaa actacactaa aaatcaagct aattaatatg
    27781 aaaagaggga atattgaatg tataaagtga cacttatacc aggagatgga ataggaccag
    27841 aagttgcgaa agctatgaaa aaggtagtag aagctactgg agtagaaata gaatgggaag
    27901 aagttaatgc aggagaggca gttattgaag agtatggtac tccacttcct gaatatatta
    27961 tagatagtat aaaaaagaac aaaatagcta taaaaggccc aattactact cctgtaggta
    28021 aaggatttag gagtgtaaat gtaactttaa gacaggcatt agatttgtat gtcaatttaa
    28081 gacctattaa aagttttaag gggataaaat caagatatga agatgttgat ttagtggttg
    28141 taagagaaaa tacagaagat ttatatgctg gaatagaaca taaaataggt gattatgcag
    28201 ctgaaagtat aaagataata acaagaagtg caagtgaaag aatcgttgat tttgcatgta
    28261 actatgttaa agataataag agaaaaaaag ttacagctat acataaggca aatataatga
    28321 aaatgtctga tggattgttt ttagatgtgt ttagagaagt tgcatcaaaa catggtgtag
    28381 aatatgatga tttgattgta gatgcagcag ctatgaactt agttttaaat ccagaaaatt
    28441 atgatgtaat ggtaatgcca aatctttatg gagatatact atcagattta ggtgctgggc
    28501 ttgttggagg tttaggtata attccaagtg caaatattgg taaagattgt gcgatatttg
    28561 aagctgttca tggaagtgct ccacaaatag caggtcaaaa taaggctaat ccaacagcac
    28621 ttattcaatc atcagtaatg atgcttagat acttaggtga atatgaaaat gcacaaaaaa
    28681 tagaaacagc tttagaaaaa gtatttcttg aaggaagtaa attgactgta gatttgggtg
    28741 gctcagcttc tactacagag tttgcggatg aggtgtgtaa gtatattgta tagattttat
    28801 ttagggaaaa agtaaaatat agattgaagg aaagaggctt tctcaaaata gagataagcc
    28861 ttttttattg gaatgataaa atatatttga ttttatacaa aagagagttc ctcataaacg
    28921 aaaaagttaa ttttgggata tccattttaa ttttaaaatt aattgattaa tatgcaaaga
    28981 aagattaaat aaatttatta tttttaattg aactttcaac caaaatatgg taaaatttaa
    29041 aaaagttgaa ctttcaacta aaaatgaata tattgattat gtgaaatttt ataaaacaga
    29101 aactatttga ctttagccat agtagtttca gtggaggtgt gtttgattaa gactttagat
    29161 agtaatatat taagagaagt aggtacttta tctagagcag taaattcaat aaatgatatt
    29221 aagtacaagg aattaaagtt acaaaaagga caatttacat ttttgacaag aatctgtgaa
    29281 aatcctggta taaatcttgt ggaattatca aatatgttaa aggtagacaa ggctacaaca
    29341 accaaggcta tacaaaaatt aataaaggca ggatatgtag ataaaaagca ggataagttt
    29401 gataaaagag gatataattt aactccaact gataaatctt tggaagttta tgagttgata
    29461 attgaagaag agaatagaag tatagagata tgttttgata attttacaga tgaagaaaaa
    29521 caagtggtaa ctaagttatt agaaaaaatg agcaaaaacg tagaaaatga atggtttaaa
    29581 gtaaagagat agtaaataaa tacattaact taaggagata tttttatgat tagaaaagcg
    29641 aatatgaatg atttagaaag cattatgcaa attataaaat ctacagtgga agaaatgaag
    29701 acttataata atacacaatg ggatgaaaac tatccattag aaaaagactt tgtttcagat
    29761 attaagaaac aagatttata tatttatgaa gtggatggag aagtagcagg gtttatatgt
    29821 cttaattatg aagagccaga agaatattta ggcttaaatt ggtcatctaa taaaaaagca
    29881 atggtaatac atagaatggc tgtaaatcca aactttagaa agacaggaat agcatctaag
    29941 ttagttgatt ttgctgaaaa attagctgta gaaaacaatg tatcatactt aaagagcgat
    30001 acatattcaa taaactcaaa aatgaattta ttacttacaa agtgtggttt tataaaaatc
    30061 ggagaaatga gttttttagg aaaggagaaa tctttctact gttatgataa aatattataa
    30121 agagcattta taatacaagg gataaataat agattttcag cattagtaag ggcataatat
    30181 aacctagtgt atgctattat gaaagggatg atttatatga ttggatttct aaagaaaaga
    30241 agaagtatta gaaaatacaa ggatgttgaa gtagaaaaag aaaaattaga taaaatatta
    30301 aaagctgctc ttttagctcc atcatcaaag gggcttagaa catgggaatt tatagtggta
    30361 gatgataaag aaaagctaat taatttatct caatgtagaa ctaaaggtgg tggatttttc
    30421 ttaaaaaatg cacctttagc tattgtaatt attgcagata aagaaaaaaa tgatgtttgg
    30481 atagaggatg caagtatagc tgcttcatac atacaacttc aagctcatga actaggttta
    30541 ggttcttgtt ggatacaagt aagaaataga atgcatgatg ataatataga agctgataag
    30601 tacattagag aagaattaaa agtacctagc aagtacagtg tagaatgtat aatttctata
    30661 ggatatcctg atgaagaaaa gaaagcatac ggtgactctg atttagacta taaaaaggtt
    30721 cattttaaca acttttagta tataatatgt tgtattaaga cattatattt ttttctattg
    30781 ttaatatata cttaaaattg taaaaatata tctgaatttt actaacttat ctaggggtta
    30841 tgtacaagga ttttaaagat aaatatagaa attaatgttt ataatcgata cataacttga
    30901 gtaacaaaat ttaaggaggt taaagtatgg gtatatttaa aacaaaaatg gatgaggact
    30961 ggaaagtaaa ctacattaaa gagtttaatg aaatgagaga ttcttatgag agtaaacttc
    31021 aaaaaaaaca gtttgaggta gatagtttga aatcagaatt ggatagacta agaagctata
    31081 aaaatagcct taagccaaaa gaaaaacaaa ttactgatga tgatataaat aatataaaga
    31141 gtttaagaag agatggctta agctataaag aaatttcaaa tcaaacaagt tggagcaaag
    31201 caactgtaag tagggtatta aatggacttt acgattagca tatacatggg gtgatttaaa
    31261 ttgggatgaa gtatagttac aaaaaatgca taatagattc tattttattg atgtttatag
    31321 ttcaaatatt aaggatgatt ttgaattatg tacttctaag tcaatttgaa tttactcttg
    31381 aaaattttaa tattataaac ttaatttctt ttacattagt tggtttatcg ttaattttat
    31441 ttttaaaaga taattctttg tataacaagg ttagaaatag aaaaatcaca gaagcttttg
    31501 aagaaaataa aaacaatata cttattgaaa agtgtaagct gatacttttt gttgtggttt
    31561 tatctttagc aataattgta acttattgta ctaagggata tgtacttttt aatgtaacta
    31621 tgatgacttt gtctgtattg atagtcccaa tatttgaaga gttatttttt agagaatata
    31681 tatggaacta tctaagtaat tttataaagt caaagagtaa aattatctgt ataacatcta
    31741 tactatctgg aatttataat ataggataca tagatgttat aagaaattat gtaatattgt
    31801 ataacaattc aagctacacc tttgaagtta ttatttcaaa aattatgata ggtactgttt
    31861 ttggtattgt acttggatta gttaagtata ggtttagaga tgtagggttt tgtatattat
    31921 tgaggagctt atttgctata tttattaggt agatagtata atcggtttat aaggttgttt
    31981 taaatttaat tttaaatcaa ccttatttta tttgtgtttt ataaagcact tatatattaa
    32041 taactaataa atttaataaa aattatttga atatttttaa aatatataaa tatgtattga
    32101 catataaata ttatgaatta caatttatat aaactaataa aaattaaata atattaatca
    32161 acttattgaa tggaggaata aaaatgaaat ttgtgacttt ttgtagtagc aatgaagaaa
    32221 aaataggtgt atttaattca gaaacaaata gtatatatga aattaatagt ttaggattaa
    32281 gtaaattata tactgatatg aatgatttta ttgaaaacgt atctacagga gatttagaaa
    32341 aaataaaaaa caattcattt gaaaacgcaa agtgttataa gttagaagaa gttaaattat
    32401 gttccccaat tgtaagacct aaaaaagata ttatatgttt aggtctaaac tataaagacc
    32461 atgtcaatga aatcccagat ggagttataa aaaacgtagt tatgccagat tatccaattt
    32521 atttttctaa gagagcagac aaaataattg gagtggatga taagataagc ttacatggag
    32581 atttggtaga gaagttggac tatgaatcag aacttgcagt aatcataggt aaagaaggta
    32641 taaatatatc aaaagaagat gcttatgaat atatatttgg atatacaata gtaaatgata
    32701 taagtgaaag agcacttcaa gataaacatg ttcaatggtt tagaggaaaa agcttagaca
    32761 cacatacatc tatgggacct tgtatagtac ataaagaaga atttgaacat cctttaaaat
    32821 tagatataag tagtgtagta aatggagaag taagacaaga ttctaataca gagtacttta
    32881 tatttgatat acctactata ataaatgatt tatcaagagg aatgactcta aagccaggag
    32941 atataatttc aactggaact ccagcagggg ttgctatggg gatgaatcct caagtatatt
    33001 taaagcatgg cgatatagtt gaatgtaaag tcgaaggaat aggagtttta aaaaatatag
    33061 ttgattaatg gataaatatg ccatataatt ttattagtac gaataattta attaatatag
    33121 gattaatcaa acttatgatt aatttattat agagagggat gagtatatgg caagagaact
    33181 agaattaaag tatggctgta atccaaatca aaaaccatca aagatttata tgaagaatgg
    33241 agaacttcct atagaggtat taaatggaaa acctggatac ataaattttt tagatgcatt
    33301 taatagttgg caacttgtga aggaattaaa agaagctaca ggtcttccag cagcaacttc
    33361 atttaaacat gtaagtccag caggagcagc agtaggggta cctttatcag atactttaaa
    33421 gcaaatatat tttgttgatg atttagagct ttctccatta gcttgtgctt atgcaatggc
    33481 aagaggagca gatagaatgt cttcttatgg cgattttata gcactttcag atgtatgtga
    33541 taaggagact gcaactatta tagcaagaga ggtttctgat ggtataatag ctccaggata
    33601 tacagatgaa gcccttgaaa tattaaaagg aaagcgtaaa ggcaactata atattgtaaa
    33661 aatagatgaa aattatactc ctgaacctat tgaaacaaag gatgtttatg gaattacttt
    33721 tgaacaaggt agaaatgaaa tattaataaa tgaagaccta ttaaaagata ttccaactga
    33781 taataaaatt tttacagata gtgcaaaacg tgatttaatt atagctctta ttacattaaa
    33841 atatacacaa tcaaattctg tttgttatgc taaagatgga caagtaatag gggtaggtgc
    33901 aggtcaacaa tcacgtattc attgtactag acttgcaggt aacaaagctg atacttggta
    33961 tcttcgtcaa catcctaaag tattaaactt aaaatttaaa aaggatatag gtcgtccaga
    34021 tagagataac actattgatg tatatctttc tgatgattat atggatgtgc ttgctgatgg
    34081 catatggcaa aacttttttg aagaaaaacc agagcctcta actggagaag gaaaaagagc
    34141 atggcttaaa actttaacag gagtagcact tggttcagat gcatttttcc catttggaga
    34201 taatatagaa cgtgcaaaaa gaagtggggt aagttttata gcacaaccag gtggttctat
    34261 tcgtgatgat aatgttatat taacttgtaa taagtataac atagtcatgg catttactaa
    34321 gaatagatta ttccatcatt aaaatactga aagtataaag ataatataga ttaagtaaaa
    34381 atctacaaca agttttgttg tagatttttt tatttgctgt ataattttaa atagaacttt
    34441 atttttagat attcaatttg gaggttgata tggctttaaa tataagaaac tatagcctat
    34501 tatgtaatca aggaacagct aaatttaatg aagatgtagt cggtataaat ccatttgggg
    34561 catgggtttt agatggtgct acaggactta atggaaaaaa tttagtgtca actgaaagtg
    34621 acgcaaggtg gtatgttcag tggtggaata ggtatttata taaaaatata aataaagaag
    34681 aatcattaaa gagtattatt aatactggaa taatagaagt aaaaaaagag tatgaactaa
    34741 gattaaatgg gtttaaggtt gaaaaattag atttaccatc tagttctata gttgttgtaa
    34801 aatttcatga aaataaagta gagtattttt tattaggaga ttgtgctttg tttattaaaa
    34861 atggagattc caaagttata aaagatagga gtatttgtaa atttgataat actgtatttg
    34921 atgaaatgag taaactttct aacttggaag agatggcatt tgatgagatt agaactagtg
    34981 ttatggatac aatagtaagc aatagattga agaaaaatac aaaagagggc tattggatat
    35041 tggattttga tgaggaagct gtggaaaatt ctatatatgg atacattgaa ataaaaaaag
    35101 attttcaatt gatgctaacg agtgatggtt ttacaagtgc atgtgataga tataatctaa
    35161 taaaagaaga agaattgata cgtatagcag aaaaatttgg tataggatat atacataata
    35221 aagtaaggga ttttgaagat aatgactata aagcggttaa agtgccaaga tttaaagtaa
    35281 aagatgattc atcttgttta tatttagata tatataatga ttagactgta taaaactatt
    35341 taattttaga aaggaggcaa gtgaaaagtg aaaattcttc atataataac acaaaaacca
    35401 aatagtacag gtagtggtat atatttgtct ggtatgataa aaggattcga aaaaatcggt
    35461 cataagcaag ctgtaattgc aggtatagat gtaaatgatg atgtaaattg ttttccaagt
    35521 gaagtaagtt tttatccagt aaagtataat tgtggggagt taaattttcc tgttgtaggt
    35581 atgagtgatt ctatgccata tgaaagtaca agatataaag atttaaatat agacatgata
    35641 aatagattga aatatcaatt taaagtaaat atagataagg ctatgaatga ttttaaacca
    35701 gaacttataa tatgtcatca tttgtacctt ttaactgcat ttgttaggga aatggtaaaa
    35761 gatataaagg ttatgtctat ttgtcatgga acttgtttaa gacagttaaa taccattgat
    35821 ttagagaaag aatacataat agcaaatata aggaaattag atttaatatt tgctcttcat
    35881 gaaaatcaga aatatgatat tataaagact tttggagtaa gtcaaagtaa agtagttgta
    35941 attggtagtg gttataatga tgatatattt tataataaaa attataaaat aaaggatgat
    36001 aaaataaaaa tagtatttgc aggtaagata tgtaaatcaa agggactgat tccatttata
    36061 aaagctatat ctaaattaaa atatagtaaa gatttaatag aagtcaattt tgcaggtact
    36121 ggaagcgata tcgaatcata taatgagata gttaaactgg caagtaagtc tccatttaaa
    36181 atgaatttcc taggaaagtt agaacagaga gatttagctg agctattcaa caggtcacaa
    36241 atatttgtgt taccatcatt ttatgaggga ttaccagttg tagttttaga agctttatct
    36301 tgtggcacag atgtaatcac tactgatatt cttggtgtta aagagtggat tggtagtgag
    36361 attaataatt ctggaaagat agaatatgtt tctctacctt ttatggagaa agaaggtatt
    36421 ccaaaagatg aagagttata tgattttgaa aataatttgt ataatgcaat agattctaag
    36481 atacaatctt tattgaataa ctcaaataag aaaacatctg tagatatgtc aaaaaaaacg
    36541 tgggatggct tagcatatag aataaatgaa gttattttaa tggatgaatt gtgtttaatc
    36601 taaaattatt taaattataa aaaagtgtaa ctatttttac actattttta aatgatttta
    36661 tattatacta atactaaata tatttgtttt agggaggtaa tttatgagga ttagtaaaaa
    36721 ggtattggcg ttaggtattt cagcattact gttaagtgtt agttttccaa catcaataaa
    36781 cgcactagat aagattgaaa atattcaagg agtagataaa tatgaaacag ctgggcttat
    36841 ttcagataag caagatttta caacagcagt tcttatcaat gcagattcta caatggtaga
    36901 tgggattgct gcaagtggtc ttgcaggagt aaataatgca gctattttat taactaataa
    36961 ggatgatata ccagaagcaa cgcttcaaag actgaataga gttactaaga tatatgtaat
    37021 aggtggagaa aattctataa gtaaagatgt agaaaaaatg ttacttatga gaagaatgca
    37081 agttataaga attgatggtg tagatagagt agatacaagt tataaaattg caggtgaaat
    37141 agaaaaaatt aaaaacagtg ataagatgtt tttagtaaat ggatttaagg atgaagctga
    37201 tgcagtaagt gttgcatctg ttgcttatag agatggagct cctataatat tgacaaaaga
    37261 tataccttca gcagaagaag acacagactt agacccatgg tttggagttt ctcctgttcc
    37321 agtatatgct attggaggag agtctacatt aagtgattac atagtgagca gatatagagc
    37381 aactagaatt ggtggtgttg atagatatca aactaataaa aatgttattg aaaagttcta
    37441 taatggagca aaagagttct atataacaag tggagacgat ttagtttatg ctttagttgc
    37501 atcaccactt gcaaaaaatg ctcctgttgt tttagtttca aataaaagtg ataagagtat
    37561 attaagtgga gctagtaaag taacagcaat aggtataagt gataagagta ttatagagca
    37621 atgtttggat gctgtaaaga agtaatggag tgttattagt aaaatgaata tacacattga
    37681 aaattagtag attgttcatt ttataatggt ataaaatata tgggaagagg ctatcaaatg
    37741 gagataagcc tctttttcat tgttaaaatt atgaaaagat actttatttt atataaaaaa
    37801 gtatcttatg aactaaatgt ctattttgat atactatctc cttttcttat attatatgat
    37861 tttttatatg gaataaattt cataagtatt atcttccttt aatttttcta accaaaccat
    37921 ctctaaaata tctagttctt ctaaataatc tttctctgtt ttgttatcat catgttttat
    37981 aagttctaaa acttcaaatg taaatgcttt ttcaccatat tttttccatt cattatttaa
    38041 ttcttttatc atacatgagc cagcaccaag ctgaaatttg agagagttaa atttgctttt
    38101 tatgtcatta ctttttccaa ggtaaatctt tttagtaata tcatttttta ttatgaatac
    38161 acctgtgtca aatttcattt ctttgtataa ttgttttaat tcacgttttc tatccatgat
    38221 tttagatacc tctctttata attgatatgt aatatgtaag tgtaaaaata tattacatat
    38281 caattataaa gagattaatt ttatatgtaa atagttttta taaatttaat tatgaattag
    38341 tcatcaataa acaagaaatt tagctctaga aatccattat aaaggctatt ataaatttta
    38401 atatgctaaa aatataaaaa gaatagttga cagtgtagaa aatatggaat aaactaaaag
    38461 tgtaatagta atatgaaatt atatattaca ttgaaaggtg tgaatgatta ttatgaataa
    38521 aaaaatagaa ttaataggga attttgcaag tgattggatt aggtatagtg attatgaata
    38581 taaaattact gaagaagatg aattatatat agttccaaca gaagatgctg tgtttaccat
    38641 gtataaccca tttgatgtag cagatgatat aatagtagat ataattcgca taggacaaga
    38701 ggcattacaa gatatatcaa aagagacaaa agaaatgaaa ctaaagaaag aagtacttga
    38761 atttgtaaaa aagtatggat tattgggttt aatatattca agtgtatata atagagatat
    38821 agttggagaa gaaagagtac tgatgattga aaagaattat attacaaaag agaatatatt
    38881 gagtacagat gaatatgtaa acatgtttat accatttgca agtgatgaag atgtgtattt
    38941 taaaaagtat agaaggggta tagatgtatc aaagagagaa gaatctccaa agttttttgg
    39001 aaagagacca ttgattttag atttagtatt ttcaaagttc tacactgaac aactagattg
    39061 gattgtaagt tttgctaaag atatgtgtaa gcattttaat caaatttgtg tatataaaaa
    39121 tacatctaat ctattaactg aaagtgttac tattatgtct ggagggttta atcctcaaaa
    39181 gataggattt tctataagcc aattagataa accaattatt gcatgggagt ttgattcttt
    39241 gaaaacagct attgagacta tctatgcctt tgcaattaca agtgaacctt cttctttaaa
    39301 taaatgcaag tactgtggta aaatttatat tcctacaaat tctaaatctc aatactgttc
    39361 accttcttgt agaaattgct caaatgtaaa gaaaagtaga agtagagcca aaaaagataa
    39421 ataaaattaa taaatatatc attgtttaga ttttagtaaa taactactga attaaaagtt
    39481 gttatagaaa gttatatatc taaatgatgg tatttttttg ttgagaaaat tgaaaagttt
    39541 aattgagata gtaattttga gttgacaaaa accactttta acactactat tataagtggt
    39601 tggtaaaata atataaatta atttaagtat agcataaaaa acaaaaaaag tcaatggaaa
    39661 aaataaaaaa ggagaattta aaaatgatat cacctattat tttgagttct ataaatcaga
    39721 atttaaagga aatagaaaga aatgaactgc ttgaaactaa tatagaatct ggagattatg
    39781 gtctagctct ttctgaatct gatgtaaaag atataataaa ttcgagagat aatactttaa
    39841 aggggtatgg aagaatagaa ttagatataa aagttacaaa acagttaata gaaaatatat
    39901 atacatcaca atatacaaat gtggacaatt atttagaggc tattaatgat atgcaagaaa
    39961 ttttttatta tttaaaaaat gaaactgatg acaagatatg tgatgatgag attatagaaa
    40021 tactgggtga attttatgaa aaattttcag gcaatatgga caatgtaaga ggagaagcag
    40081 acgaatttgc aaagaaattt aaatttggag aagtttaata tatgatagga gagattttgt
    40141 atgttaaata atttaagtaa tattaatata aacgaaaata atttaataaa gaaccaatat
    40201 tccatatctc tacttaagga atgtctaaat tgtaaagtga tagatgaaag agaagtatat
    40261 aatatacaac aagaaatatc tctaatactt atggatttga ttaaaaaata tacaaatggt
    40321 caaagcacat cagtaaaaac agaagttgcc gaaaaactgt tgatttcaat atggtatgct
    40381 attgatgcat atataaataa gcttggggat atagaaaaaa gagttgtgga gttgactgct
    40441 aagaatgtta aaaaagtgta ccttggaggc attgaaatat tagaggaaga gttagttagg
    40501 ctaaaagatt tttataaact aatgatgagt agaaaattgg atactaattc aatagcatat
    40561 aatgatacct tgatggagtt atcaagtttc tttaaaagtt atattgtaaa atttgaagct
    40621 caggacgttc cagtaagtat agattatcca ttggcactag atgatatgga tgttaagggt
    40681 atttattatg tgaagaatta tattgagagt atagatatag aaaatagatt ttgtaaccta
    40741 tttaagaaaa aagatagaga aaaattattt tatgactatg gggtgactta taaaatagat
    40801 tgtgatgcta tacttgtaaa tttatttgaa cttattataa ataattgtat tttttctact
    40861 attttaggaa atgaagtgac taatttagaa atttcaaaat atgagtatga attt
//
LOCUS       DAEPKC010000026        38886 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.026, whole genome shotgun sequence.
ACCESSION   DAEPKC010000026 DAEPKC010000000
VERSION     DAEPKC010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 38886)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38886)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38886
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.026"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(269..1423)
                     /locus_tag="KR294_001439"
     CDS             complement(269..1423)
                     /locus_tag="KR294_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH0239521.1"
                     /translation="MINKAIKFKFIIFYFFSYIIFAFASTKFTPFLSKLGYSAFERGI
                     ILSSYAITNILFQLLFGVLADKYQTMKKIVLISLSVYGIASVIMFSTESATFIIYLLL
                     VALSGGLLNTCCSLYDTWIIGCGDNINNYLSFIKTFGSIGWAIGSMVASYLILRFSYF
                     GLSVAIGLIVVLLIINILLLPDIEKINKKINVTNKDIIELLKDKKYILLVCILFLLYS
                     MVVANNCTVIDKMIALNATNSQISLKWSLQSLLEIPTYLAGSYLLKKYSSLNLLKLSA
                     IMITVQFLLFALTNDSNIIIILCVFQVFSTPLILITSKRLIFEVSPKKLRSSSQLIAL
                     SIFMGGSSLIIPTVAGFLSINIGYNYTLMVLSLFGCLAYCLIVLLNYLQE"
     gene            complement(1426..1893)
                     /locus_tag="KR294_001440"
     CDS             complement(1426..1893)
                     /locus_tag="KR294_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBH0239522.1"
                     /translation="MFFKRKKEAITINSYIDGKIINLGEIPDKVFSTKVMGDGFAMIA
                     KDNILKSPTKGVISFIAQTNHAIGIKLQNDVQILIHIGLDSATTKKENFKLEVKQGQE
                     VNMGEKLVEIDNKLLENTLYIPLVIVENPNTVKYHLSNLNQEGNSGIKVINFD"
     gene            complement(1907..2395)
                     /locus_tag="KR294_001441"
     CDS             complement(1907..2395)
                     /locus_tag="KR294_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239523.1"
                     /translation="MITNKIKNITAVLKDENIFLSVVMVCFLILPVLYIVYLELTSLF
                     TNISFSQLLNNDVNASLNLISNFSAVYSAYVIYNIKKNKEIKENMIAFYLVLLGQIFQ
                     IYTITIVIMFTYIYKFVGIKQIISSIKELQWGKSYKALFSSIAVCLISLFVMIIRIKL
                     IM"
     gene            complement(2409..3740)
                     /locus_tag="KR294_001442"
     CDS             complement(2409..3740)
                     /locus_tag="KR294_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HBH0239524.1"
                     /translation="MERKRQRILIAGGGSTYTAGIVTMLIESVAKFPIESIKLYDNND
                     ERQRKVAEACAIIVREKNPEIKFSYTTNPEEAFTDIDFVMAQIRVGLYALREQDEKIP
                     LKYGVVGQETCGAGGIAYGLRTIGPIIEMIDYMEKYSPNAWMLNYSNPAAIVAEACRV
                     LRPNSRIINICDMPVCLEEIFARVLGLNSRKDFDVRYYGLNHFGWWTSIKDKEGNDLM
                     PKLQEYCAKKGYEEFTPQGQHKESSWLETMRAAKDLLEIEPTTLPNTYLKYYLMADET
                     VEHANPNYTRANEIMDRREKDTFEECERIIKNGTARDTWFDASEHSQFIVELACALAF
                     NTQERFLLIVPNNGAIENFADDAMVEIPCLVGKDMVEPMSIGKIPTFQKGLMEQQVAS
                     EKLAVEAWIEKSYQKLWQSFTMSKTVPSAKVAKEILDEMIVANKDFWPTFK"
     gene            complement(3754..5319)
                     /locus_tag="KR294_001443"
     CDS             complement(3754..5319)
                     /locus_tag="KR294_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003233606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBH0239525.1"
                     /translation="MMKKIQRFGGAMFTPTLLFAFAGIMVGFSIVFQNQSIMGSLATP
                     ENIWYQFWGVISSGAWMVFNQLPLLFAISLPIALAKKQQARACMEALATYLTFNYFVG
                     SMLSFWGKSFGVDFAAEISAGSGLVSIAGIKTLDTGMVGALLISGIVIYIHNRFYDKE
                     LPDFIGLFRGSSLVVAICFFVMIPVALLTCFIWPHIQNVIRHLQTFFINSGNIGVWCY
                     AFLQKILIPTGLHHFVYAPICYDSVVVPGGTSVYWATHIQDFQTSAKTLKEMYPIGFS
                     LSGLSKVFGSLGVFGAFYVTAKPEKKKKVLGLMIPATLTAVLTGITEPLEFTFLFVAP
                     LLFLVHAFLDACLQTISFALGVVGDFGGGIINWVVLNWLPLGMYHWKVYVVQVVVGII
                     FSFIWFFVFTFLIKKFDMKTPGREEDSEETKLYTKNEYLETKDEKGNKLSKASQQASE
                     YIKLVGGAENVVDVTNCATRLRLTLKDDSIISKEEDFKAVGAHGLVHNGKAIQIIIGL
                     SVPSVREEFENLL"
     gene            complement(5489..6274)
                     /locus_tag="KR294_001444"
     CDS             complement(5489..6274)
                     /locus_tag="KR294_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBH0239526.1"
                     /translation="MRLEEMIFLNYNKLNDTDLLIWKYITANKKHCSKMSINELAMKC
                     NVSRATITRFVKKLDLKGFSEFKVLLSWESEKVHVIENQSFDIACNSIIKYVEDQKNK
                     DYDALCKLLYESRTIYAYGSGDIQNVVAKQIKRMFLSCQEIIYDFEGRTFDDSFYNIV
                     SKNDVMIIISLSGENENTLNIARRLKLIGTKIISITEFKNNTLTDLSDESIYISATNI
                     SFLQMHPSYKLTMLYFILIELLFIKYSIYKRHRMITEGIDCKL"
     gene            complement(6441..7640)
                     /locus_tag="KR294_001445"
     CDS             complement(6441..7640)
                     /locus_tag="KR294_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S41"
                     /protein_id="HBH0239527.1"
                     /translation="MKKKVLFLVIILAFIILLGNSTYSQKNQLSEEEKVDDFNYVYNV
                     VKTGYPYLGVNKRLNNIDWLANKDEYTKRIKNTENDEEFIEEMSSILSDLNNKHTEVI
                     DNKKRYELFKKSYSNNDWYDFLNDKKVVDRYDSMNLKIKMPDDIFVKKELILKDVIKG
                     QIGYMYLPSMSSKNGSINNDLKIIGDYIDTLEKHKALIIDIRGNLGGSDSYWQGIVSK
                     LIKNDVKINGYRIYRNNNEIVKQYTNARNIKLNPVENLPTSVKENAPKEIIKDFNDFE
                     DTSYTIKSTDDSKFKGNIYLLVDRKIYSSSESFAMFCKETKFATLVGETTGGDGGCID
                     PVLFNLKNSGLIVRMASCMYLNKNGICDEEFKTIPEFKVKDCKRTADFKDDNCIRKAL
                     ELENINY"
     gene            complement(8162..9499)
                     /gene="xylA"
                     /locus_tag="KR294_001446"
     CDS             complement(8162..9499)
                     /gene="xylA"
                     /locus_tag="KR294_001446"
                     /EC_number="5.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylose isomerase"
                     /protein_id="HBH0239528.1"
                     /translation="MSEIFKGIGQIKFEGVKSDNELAFRYYNPEQVVGNKTMKEHLRF
                     AMSYWHTLCGEGNDPFGVGTVERPWNNITDPIEIAKIKVDAGFEFMSKMGIEYFCFHD
                     RDIAPEGRDLEETNKILDEIVEYIKVNMEKTGIKLLWGTANMFGNPRFVHGASTTCNA
                     DVYAYAAAQVKKAMEITKYLGGENFVFWGGREGYETLLNTNTELEMDNFARFLQMAVD
                     YAKEIGFTGQFLIEPKPKEPTKHQYDFDTATVLGFLRKYNLDKYFKMNIEANHATLAG
                     HTFQHELNIARINNVLGSIDANQGDLLLGWDTDQFPTNIYDATLAMYEVLKQGGIAPG
                     GFNFDSKVRRASFEVEDLFLAYIAGMDTFAKGLLIAHKLLEDEVFENFTKERYASFSE
                     GIGKDIVEGKVGFKELESYALQMPVIKNKSGRQEMLEAILNRYIYEVDTISNK"
     gene            complement(9595..11145)
                     /gene="xylB"
                     /locus_tag="KR294_001447"
     CDS             complement(9595..11145)
                     /gene="xylB"
                     /locus_tag="KR294_001447"
                     /EC_number="2.7.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylulokinase"
                     /protein_id="HBH0239529.1"
                     /translation="MKLEYVLGVDIGTSGTKTVLFDKLGNTIKSCTYEYPLIQEKSGW
                     AEQDANDWWKAVVESIREVVQSSNISSECIKGIGLSGQMHGLVMLDNEGKTLRNSIIW
                     CDQRTVKECEEITDLVGEERLIEITANPALTGFTASKILWVRNNEPDIYKNTNKILLP
                     KDYIRYKLTGEYATEVSDASGMQLLDIRKRDWSDEVLEKLNIDKNLLGKVYESQEITG
                     YVTRDVASLTGLKEGTIVVGGAGDQAAGAIGNGIVKDGVVSSTIGTSGVVFAYTKEPK
                     IDKEGRVHTFCHAIPNTWHVMGVTQGAGLSLKWFKDNFCQSEVEVSNSLGEDVYEIIN
                     NQVSQVPTGCNGLLYLPYMMGERTPHLDPYARGVFFGLSPIHSKKEIARSIMEGVSYS
                     LKDCMDIIENLNIDVNEVRASGGGGKSKVWRQMQADMFNQDVYTINSSEGPALGVAIL
                     ALVGAGIYENIQKACDAIIKTSTKLEPISENVDTYNIYHRLYKRIYKSLKDDFKLLDE
                     VVNAKINN"
     gene            11353..12513
                     /locus_tag="KR294_001448"
     CDS             11353..12513
                     /locus_tag="KR294_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HBH0239530.1"
                     /translation="MVTDKYTIREMNERLVLEQIIKNGPISRASIASTIGLNKATISA
                     ITKKLIDESLVHEIGIGNSTHSGGRKPILLVFNKCAGISLSMDIGYDYIFSSLSYLDG
                     TIINSKKLTDIQVSKDNVIQLIDEIINSYNISKIDTPYKVIGLTLAIHGITCENKVLF
                     TPYYNLNEIDLYSILSKKYDFPIHIENEANLTALAENTFSTVHNSLLSLSIHSGFGSG
                     IIINNKLYSGRNGMSGEIGHTIIMPNGKLCPCGNRGCLEQYCSEKKVFEQLSSLENIP
                     KIDSDIVKQLYYEDNHNAKKVIHEFCSYLTIAINNAITTYAPEIIYLNSQIISDIPEI
                     LQITKDMLVSSFNKGINIEISSLGSEASLYGGSAVNIKSFLNIQNLTLINEI"
     gene            complement(12669..13073)
                     /locus_tag="KR294_001449"
     CDS             complement(12669..13073)
                     /locus_tag="KR294_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH0239531.1"
                     /translation="MNSIILMSHGNMAEEVLNSAKMIIGDSIDYPTVNMKQDDGIEGT
                     IEKLKKALEVYKESSEIIIMADLLGGTPCNAALLVANNDSRIKIISGLNLGMVIESAF
                     LDTKELAAKLEKIGKDNISMVEQNASLLSDDE"
     gene            complement(13094..13576)
                     /locus_tag="KR294_001450"
     CDS             complement(13094..13576)
                     /locus_tag="KR294_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH0239532.1"
                     /translation="MEMKGIKNIRIDDRLIHGQVATMWSNKLGVTRLMVVNDAVANNS
                     VQKQVLRMATPAGIASSIITEETAIKNITAGKYEGQNVLLIVKSPVDLIPFVEAGFKI
                     HNINVGNMSSRKDTTVLRPNISVTEEEKEAFKRLLDEGIEITTIMTPDDKKTYLVDIL
                     "
     gene            complement(13596..14405)
                     /locus_tag="KR294_001451"
     CDS             complement(13596..14405)
                     /locus_tag="KR294_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBH0239533.1"
                     /translation="MSDKVSLNKSNEKVKKSVLWRWFFTSSVSSNYEKMQALAYCYAV
                     LPFLKVVYKDNPEKLQSAVLNHLQFFNTNPWVAPYILGINVAMEELSSEETEEAVASI
                     KTGLMGPVAGLGDSLFVVIPWTIFGAIAANMAIDGSPFGILLWIVVSVALKLLSIPLF
                     NAGYTSGTKLISSIEKSLKILTESTSILGLMVVGALIPSVVKANVALNFQQGDFTMKG
                     QEILDQIMPGLVPAILVVIVYWALKKNIKPIYLILGVMVVSIILYALGILK"
     gene            complement(14398..15177)
                     /locus_tag="KR294_001452"
     CDS             complement(14398..15177)
                     /locus_tag="KR294_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH0239534.1"
                     /translation="MEPQLWQLLLIVLYGFFINYEKNSTMFGTYQPVTAGFITGLILG
                     DINTGLYIGGTLQLLSLGISNFGGASIPDYQTASIVATFITITTKQEASVGISIGIPV
                     ALLMVQLDVLRNTIGIWLVHKAEDGAKKGNYKNITYMQMLGVLLTAATTGIPVALSVI
                     FGPSLINTILKYTPEWLTGGLTVAGGLLPAVGIGLLLRYLPAKEYFSYLVIGFVLAVY
                     MKVPLLGVALIGGAIALIIYKKNLENQEQQYTVVGGMDEDE"
     gene            complement(15177..17255)
                     /locus_tag="KR294_001453"
     CDS             complement(15177..17255)
                     /locus_tag="KR294_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HBH0239535.1"
                     /translation="MIKISEDYIEKRFDNELLRIEAWGKNSLRIRSFVDQNFVDENYA
                     LNEKPKLNKDDITINKNEDGSAIIKNGKIKAVLDHRDRITFYNDKNEILLKEYIRLRA
                     VKHDDGGEDVGTIEITKDFNSTLKLKSREYRPSYSGEFEVTTRFESEPSEKIFGMGQY
                     QHKFLDLKNTVLELAQRNSQISVPFYISSLGYGLLWNNPGIGKVSFAKNMTEWKMFST
                     NFIDYWITCGESPKELNKNYSQVTGTVPMMPENLLGLWQSKLRYRTSEEVLDVVKEYS
                     KRGIKLSSIAIDYFHWPKQGEYKFDLDYWKNPKELVKKLKEEYSVEPIVSVWPTVQSD
                     AENYNDYLENGYLVNVNRGVRMTMQIQGNTVFVDMTNENAREYVWDRIDKNYKQLGID
                     YYWLDVAEPGYSVYDFDNYRYKKGNVLSCGNIYPIDYLKMIYDGLHNDIESVVTLVRG
                     AWAGAQKYGALVWSGDIDSSFEAFNNQVNTGLNMGLAGIPWWTTDIGGFHGGNPKDPE
                     FRELMVRWFQYATFSPILRMHGDRLPHSKPLSNKGGGSMVTGAPNEIWSYGEEVEVIL
                     TKFIKIRESLKTYLKKLMKEAHEDGTPVMRTLFYEFPEDDKTWEVDNTYMLGDEILVA
                     PIMNYKDRSRKVYLPKGHTWENIFSGVSYEGGKTYEVECPLEEIPIFLKQDSSYNFKE
                     LKNILGEVKS"
     gene            complement(18054..18575)
                     /locus_tag="KR294_001454"
     CDS             complement(18054..18575)
                     /locus_tag="KR294_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HBH0239536.1"
                     /translation="MKRNREIVVVCHCILNCNSKVEGLSEFKGAQNIAIDLINKGYGI
                     IQLPCPEMIMYGINRWGHVKEQFDNLFFREQCRQMLIPHVRQFDEYLKNDYDIKSIIA
                     IDGSPSCGYNKTCSSKRWFGELSGCNELMDKINDIQMVDGKGIFIEELEKLLKEYNLN
                     IPIVGFDELREDK"
     gene            18741..19307
                     /locus_tag="KR294_001455"
     CDS             18741..19307
                     /locus_tag="KR294_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBH0239537.1"
                     /translation="MDTKKVTFSSMCIVINIVLGMVISMINIPLLFLDTIGTVLGAVV
                     LGPFWSALIGGCTNLVLGVISGPTNIPFALVNIVLGLIVGYISKKKGFGYKEAIITGV
                     ILSIVCPLIGTPISVLLFGGLSGSGADLLVGFLVQSGQKIFTAAFFPRILSNIVDKPL
                     SCIMVVYFISKMPKGFIKQYSKNTSSSY"
     gene            complement(19524..21587)
                     /locus_tag="KR294_001456"
     CDS             complement(19524..21587)
                     /locus_tag="KR294_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF262 domain-containing protein"
                     /protein_id="HBH0239538.1"
                     /translation="MKAGEIEFLSYLEGSNKSFVVPVYQRNYNWKKEQCKRLFDDLED
                     IIDSGFRTHFLGSVVSIYSMGKEYLIIDGQQRVTTVSILLIAMCQIIKEFGESKGIIT
                     TEEQIKECYLINKHSRDKDGKIKLKPIAEDRKAYYELFEEEMNTDRNSNIVSNYLYFY
                     NRIKEDNISIDDLFDAIQKLTIVEIELKNGEDDPQLIFESLNSTGLDLSEADRVRNFV
                     LMGRSSKLQEEFYNNYWYKIEKNTSSNVSSFIRDYLTIKERSIPNKNKVYFSFKRYVS
                     DNGIDIEILLKDLLKFSNYYREISYSCTDDNDVNKVLKRINKLEIFVSYPFILELFDD
                     YNEGIINKKVLVESLNLVECFILRRIVCDVPPNALNKVFMNLGREIKKFSDYKENYSN
                     ILRYIFINKKSSQRFPTDSEFSNAFETKDIYNTKSKNKLYILERLENYNNKEIVDLEN
                     LINNNMLNIEHIMPQTLTNKWKESLGDNYKEIHDKYLHTIGNLTLTGYNSKLSNKTFE
                     EKKEMEDGFKDSRLYLNKYISSIDKWNEEEIKNRTKILLDRAVEIWKYPSVTYEPPSN
                     SENIFTLEDDDVNFTNESIVSFSILGESYKAKNWTEFYEQVALTLYDLDSVRFNSIVD
                     KTYKRDFIDNIKSRDAYKLRKGIKISENIYLETNLNTEAKLNIIRFLLNEFDIELNEV
                     IFSIK"
     gene            complement(21968..25303)
                     /locus_tag="KR294_001457"
     CDS             complement(21968..25303)
                     /locus_tag="KR294_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HBH0239539.1"
                     /translation="MGNFDFLQKKKNFNSFNTACLEAEKSILVSPSTCATITRRALEL
                     AVKWLYANDSDLVLPYQDNLSTLIHNNSFIELIDYDMLPLLKYIVKLGNLSVHTSANI
                     ERGEAILSLNNLHQFVSWIDYCYSDEYTAEDFNEDLLLHGEEKRTRPDELKNLYERLS
                     SKDKKLEEVIKENEELRKSLTEKRKVNTVNYDFKIDEVSEFETRKRYINIELKLAGWE
                     FGKDIWEEIEVQGMPNESGVGYVDYVLYGENGKPLAVVEAKRTSKDPKIGQQQAKLYA
                     DCLEKRYSQRPVIFLTNGFDMYIWDDYSDRKVYGFYKKSELQLMIDRRKSKKSLSSVT
                     INDEISNRYYQKEAIRAVCEALENKQRKTLLVCATGTGKTRIAISIVDVLSRHNWIKN
                     ILFLADRKALVKQAKKSFTKLLPNLALCNLLDSKDSPEDARMIFSTYPTMMNAIDDTK
                     SKDGKRLFTPGHFDLIIIDESHRSIYKKYKSIFDYFDSYLMGLTATPKDEIDKNTYSV
                     FDMENGVPTYAYEYNKAVEDGYLVDYTSIEFKTKIMEDGIKYDELSDEEKEEYENTFN
                     DDESIGDEIGNNAVNEWLFNSDTIDLVLNKLMTEGLKIEGEEKIGKTIIFAKNTKHAR
                     AIVERFNKLYPKYGGNFVKAVDYSINYVDSIIDDFSDKNKLPQIAVSVDMLDTGIDIP
                     EILNLVFFKKVRSKTKFWQMIGRGTRLCPDLLGVDMDKERFLIFDFCNNFEFFKFNPK
                     GFEGNKTETLTEKLFNIKVSMVKELQDIKYIEGEYAELRKELLEELITSVKALNEDSY
                     IVRMNLSYVHKYKNENVWSNIGAVAQNEIREYISPLITSYSDDELAKRFDVVMYNIQL
                     AYLQNNNASKGIRHVMATAEKLSKLGTIPQIQQQKYTIEKAMTEDFWEDSDIFEVEEV
                     RISLRELIKYLEKSSQKIYYTSFEDMIVAEDRNDSVYNANNLKNYKKKVEYYLNSHKD
                     ELAIFKLRNNKKITKQDVETLEEILLKQLGNCDDYKKEFGDTPVSQLVRRLVGLDREA
                     ANEAFSEFLNNKSFNTKQIHFVKLIVDYVVKNGFIEDNKVLMEDPFRTVGSIIDLFEN
                     HIEERNKLIKTINKIKENASEIG"
     gene            complement(25353..25781)
                     /locus_tag="KR294_001458"
     CDS             complement(25353..25781)
                     /locus_tag="KR294_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239540.1"
                     /translation="MVIRNKLSWNSIEEVNRDFGSCLYDLQNFKILYDKEEMPELWAR
                     YIKEGFKSYMVSFLELTKAMLYYKSIDLNIKSKNFYDYLLACEYHNLLPKNSSIVIET
                     LRKLRNDDSHGYDIPQFEDMYELFTENEEVFVSIRNSCKK"
     gene            complement(25771..26151)
                     /locus_tag="KR294_001459"
     CDS             complement(25771..26151)
                     /locus_tag="KR294_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HBH0239541.1"
                     /translation="MRNIPNEIKNSIINVFPKENTLAIIIFGSYGTDKHTSESDIDIA
                     WIPIKKVPITELATKTEALRNILDIDVDLKIVTDNYTIALKKAILEGEVIYKSKDFKD
                     YINKFYFENSDVIDILDWRDMYGN"
     gene            complement(26184..26492)
                     /locus_tag="KR294_001460"
     CDS             complement(26184..26492)
                     /locus_tag="KR294_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239542.1"
                     /translation="MNQIELDLYHNMVNIYKEADLQCNYKPTRFLQLINNKGALLAAK
                     ELINKEGATEGFTRLWECKRLDLSLEVLVLKEKYKELFTDEEREICINRLKDYGYKFN
                     "
     gene            complement(26537..27697)
                     /locus_tag="KR294_001461"
     CDS             complement(26537..27697)
                     /locus_tag="KR294_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HBH0239543.1"
                     /translation="MEYRLNEVFEFIRNGASIKQFDTKFGYPITRIETIANSYIDTNK
                     MGYADIKELGKLEDYLLKNGDILMSHINSEKHLGKSAIYEDINKKIIHGMNLLCLRPD
                     KEVCYPKYLNYFFNSNEFRRQLPRIIKKSVNQASFSVNDLKNLKVDLPEMEAQKDISK
                     VLDKAQELIDKRKEQIEALDELVKSRFIEMFGNFKEQKFVLLKDCTNFIDYRGKTPIL
                     SENGIRIINAKSVGNGVFKYINEYISENTYNSWMKRGFPVAGDVLFVTEGHTFGNVCR
                     IPKDLKKFAMGQRIITIQGDKKILNNAFLAQYMQTKAFRVEIDKYKTGSSAQGIRSKE
                     LQKILIPVPSIELQNKFEEFVNQVDKLKVGIKTSLKELEDNFNSLMQKAFKG"
     gene            complement(27701..29164)
                     /locus_tag="KR294_001462"
     CDS             complement(27701..29164)
                     /locus_tag="KR294_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HBH0239544.1"
                     /translation="MITGELRSKVDKIWETFWTGGLTNPLEVIEQFTYLLFIKGLDEV
                     ETKNEAEATLLGVSFEKIFDDEHQHLRWSKFSNEGNSEKMYEIVQNEVFPFIKKLHGN
                     KESAYAKYMGDAIFKIPTPLMLSKIVDGISNLELSKDRDTKGDLYEYLLSKVATAGTN
                     GQFRTPRHIIDMIVRLIKPTPEDIIVDPAAGSAGFLVSSQQYLRDNHSSLFLVQGLKE
                     HFNNGMFYGFDMDRTMLRIGAMNMMLHGVDNPNIEYKDSLSEVNTDKDKFTLVLANPP
                     FKGSLDYEAVSADLLKVTKTKKTELLFLALFLRVLKIGGRCACIVPDGVLFGSTGGHK
                     SIRKEIVDNHKLEAIISMPSGVFKPYAGVSTAIMIFTKTGTGGTDKVWFYDMKADGYS
                     LDDKRNEIKDSDIEDIIKRFDNLDGEVDRKRTEQSFFVDVEEIRENGYDLSINKYKEV
                     VYEEVVYDAPSVIIGRVRELEKEIVDGLEELERMLEV"
     gene            complement(29673..30542)
                     /gene="gatY"
                     /locus_tag="KR294_001463"
     CDS             complement(29673..30542)
                     /gene="gatY"
                     /locus_tag="KR294_001463"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit GatY"
                     /protein_id="HBH0239545.1"
                     /translation="MALVTTKQILLDAQEGHYAVGAFNVENMEMVMAVIEAAEELKSP
                     VILQTTPSTIKYAGLDYYLANVKVASEKASVPVAMHLDHGSSFGLAMQALRVGYTSIM
                     IDGSHESYEDNISISKSVVDACMPSDIPVEAELGKVGGKEDDLDGGDGGAYTDPLEAK
                     EFVERTGVSSLAVAIGTAHGLYKGEPKLDLDRLSEIREVVSVPLVLHGGSGIPDEVIK
                     ESIKRGICKVNYATELRIAYSNGVKDVLNSDPEVIDPKKYGKKGLESVKDFVKSRMEV
                     CGCVGKAIEIVKC"
     gene            complement(30562..32478)
                     /locus_tag="KR294_001464"
     CDS             complement(30562..32478)
                     /locus_tag="KR294_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIABC"
                     /protein_id="HBH0239546.1"
                     /translation="MGKKMILGVTGCPTGIAHTFMAEEALKNSARELGCDIKVETNGA
                     IGVENKLTAKDIEMADAIIVACDKNVDMDRFNGKPVIEVPVKEGIHKANELIQRCIDG
                     KVAIRKGNLSSSKIAEEGNLSFGQKLYKDLMNGVSHMLPLVVAGGVLTAISFLWGIYS
                     FDPNSEQYNQIAATLKSVGGYSMNLMVPVLAAFIAQSISGRAGMLAGLVGGMISFDTG
                     SGFLGGIISGFLAGYLVKLFVHLLRKLPRQLEGLKSIFIIPIVSVGLVGVAMLLLGGP
                     CSALNNAMMNFLSGLQNSSPIILGIVIGCMSAFDMGGPVNKAAYVTGTMLLGQGNYLF
                     MAGVSAACITPPLVIAIASTLFKNRFTEEDRAAGLINYILGSTHITEGAIPFAAKNPL
                     KVLPVLMIASSISSILTYIMKIEVPAPHGGFLVLGLVNKPLLWVGCIFVGSLVGAVLY
                     MMVTPKVVNEKNTIENTNVTKDEHKNESAESENVSNNISLYSEETVILDVKGKNKTDV
                     IDEMIGILDKSSVLLDKKKFKEEILKREEISSTGFGMGIAIPHAKTDAVKVPRVAVGL
                     SKEGFDFESEDGSLAHIIFMIAATDNGDNLHLKTLSQLSSKLMNEEFLNELLNSKTSR
                     EIVSKLNNEEIKSV"
     gene            complement(32481..33401)
                     /locus_tag="KR294_001465"
     CDS             complement(32481..33401)
                     /locus_tag="KR294_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase family hexose kinase"
                     /protein_id="HBH0239547.1"
                     /translation="MIYTLTTNPAIDMNISTNGIKRKLVNRTSNAVYSPNGKGLNVTF
                     VLGHYGIESKILGFFGGFSGKYIVEESEKRGFDVLPTWVEDTTRINIFLNDGSDEFKF
                     VNSGSYVNEKQKLDMLDKIQSLEDISYLSISGSLPPGIDDNYYEDIFKICENKSIKTI
                     LDISSPKLKELLQYNPYLIKPNDEEIKDIFGIIVRDEEDIKDVLKLLHLKGAQNILLT
                     LGEKGSYFYNGKSIYYASAQPVTVVSSACAGDSALAAFLSIWLENPEHIEEALKRSAA
                     TGASVAESNGIGNLENVEDYIKNIRVRKVV"
     gene            complement(33503..34255)
                     /locus_tag="KR294_001466"
     CDS             complement(33503..34255)
                     /locus_tag="KR294_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBH0239548.1"
                     /translation="MIIELNKSNSENLTKTELEIIKFINENESILPELSIVEIAHETY
                     SSPATVSRAIRKCGLNGFNELRYRLTVKDENDDIQNMGDIINKSFIEAQRVIEQISLT
                     TLINIIKTVNKSSKIYILARGLTEYVAKEFSLKLQLLDFNVVFINDPNIMKIKSKSIK
                     KDELIIIFSLNGNTIELVESAQNANLVGAKVITCCCSESAKLIKYSDLYIVGYKHEHI
                     SISEYEVSSRLPLYIISRIIIDYMVRYNNSEN"
     gene            complement(34647..36092)
                     /locus_tag="KR294_001467"
     CDS             complement(34647..36092)
                     /locus_tag="KR294_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBH0239549.1"
                     /translation="MIKLGKFPKGFLWGGAVAANQLEGAWNEGGKGWCLADVHMYDKD
                     RDISKPYESDMTIERIKFAMKDNNGYYPKRSGIDFYHTYKEDLKLLKELGLKCFRFSI
                     NWARIFPNGDDLEPNEEGLKFYDNLINEVIDNGMEPIVTLLHYETPLNLVLKYKGWSN
                     RKVVDFFVRYAELILNRYKNKVKYWIVINQINLIHYESFNSVAFCVDQVDNVEETRYQ
                     AIHHQFIATALTKKLGKEINSDMMIGMMMADCTSYPEDCDPENVVFALKRNRLQYFFT
                     DVSFRGEYPVYIKRFFKENNINIVMEEGDDKILKENTMDFLALSYYYSTTVSASKNTM
                     NPTDNIKNPYLKANPWGWAIDPKGLYNTLSQYYDRYQKPIMIAENGFGMHDKFEDGKV
                     HDSYRIDYLGKHIEQIGEAIADGTEILAYCMWSPIDIVSCSSQEMEKRYGFIYVDIDN
                     NGNGSKKRYKKDSFYWYQNVIRTNGEELKEK"
     gene            complement(36114..36467)
                     /locus_tag="KR294_001468"
     CDS             complement(36114..36467)
                     /locus_tag="KR294_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBH0239550.1"
                     /translation="MTIEEHIIDEELVEVAMQIILRAGEARTEIKHALNDLEKFDYRN
                     ADLKLAKAKGFMTEAHRAQTKIIQGEAGGEKRAHSLLFAHAQDTLMTIFSELNITMSL
                     VGIVKSIEYKVNNSK"
     gene            complement(36496..37743)
                     /locus_tag="KR294_001469"
     CDS             complement(36496..37743)
                     /locus_tag="KR294_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH0239551.1"
                     /translation="MGRVFMNKFIDFLSEKFTPVVNNMTKNIWVQSVQSTIMKVLPMV
                     FVGSLVTIVSVLKNYISFLPDLSPINQYTFGLLGLFIAFLLPMEIMKNKKFESMSVVA
                     GLAGAGLMLMMIRPEITNEGAIFNFNRFGGEGMLVSLVAGLFSGLIMSLFGSFSFFGE
                     DSALPDFVSKWFDNMLPITVIMFVGWGLIYGLNFDMFEIIVRVFKPVSDIAQTLPGFV
                     LLNFLVVFIYSLGISGWVLSPITYSIQLGAIAANAAAVASGGVATNIYVYEVIQTGWI
                     TLGGLGATLPLVIMMCLSRVGRIKAIGRACIVPSIMNINEPVIFGAPVAWNPFLMLPM
                     WIGTVVISITTYLSMSMGFVTIPSKVFNLWYVPFGISTFTVNQDVRGLIVLAINIVLL
                     FMIWYPFFKAYEKEEIKLESQEV"
     gene            complement(37751..38068)
                     /locus_tag="KR294_001470"
     CDS             complement(37751..38068)
                     /locus_tag="KR294_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH0239552.1"
                     /translation="MKNIRVLLACGSGASTGFMATSMRKSAKKKGIEADIKARSESEI
                     DKYLSEIDCLLLGPHLDYMKEEIQQKANEYNVPVACISKTAYGRLDGAKALEEALELI
                     SNK"
     gene            38310..>38886
                     /locus_tag="KR294_001471"
     CDS             38310..>38886
                     /locus_tag="KR294_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HBH0239553.1"
                     /translation="MKTSKKELFLNFIKTQHDWIDSSTLANYLNVSTRSIRKYVNEIN
                     SNGEFILSSKKGYKVNLNNNCQTKVDSSENISPDNRLNLILKELIVNSNGINIFDLSE
                     DLFVSPATIEGDIVKANKFIGSYNLKIKQSKFLLKLIGNESAKRKLMSSIIFKETGSD
                     FLSLFDVQKIYQEYNLTKLKENIIYILKKYNL"
BASE COUNT        12688 a         7002 c         4052 g        15144 t
ORIGIN      
        1 ggttttatat aaataaatcc ttaagtaaat attacatttt aactgttagc attacacttt
       61 tgtaacatat ggaagactat tataattata gtagaaatat cttaaaataa aagcatgatt
      121 tacttctttg tataaacaaa gaaaagaagc tcctaagaag cctctaatct atacaattat
      181 tcttctctat aaaaaaccaa aatacacatt gattgtggca aatacagata ctataaacaa
      241 gtgatattac tactatatat taaaacaatt attcctgaag ataattcaat aagactatca
      301 agcaataagc taagcatcca aaaagactta ataccattaa tgtataatta tacccaatat
      361 taatgcttaa aaaaccagca acagttggaa taatcagaga tgaacctccc ataaatatac
      421 ttaaagctat taattggcta ctacttctaa gttttttagg agaaacttca aatattaatc
      481 tttttgaagt aattaaaatt aaaggagtag aaaacacttg aaaaacacac agtataataa
      541 tgatatttga atcatttgtt aaagcaaata atagaaactg aactgttatc ataatagcac
      601 ttaattttaa taagtttaaa ctgctatatt tttttaataa ataagaacca gccagatatg
      661 ttggtatctc taacaatgac tgtaaagacc actttaaaga tatctgagaa tttgtagcat
      721 ttaaagctat cattttatct attacagtac agttatttgc taccaccatt gagtataata
      781 agaataaaat acatactagt aagatatatt ttttatcttt taataattca ataatatctt
      841 tattagttac atttattttc ttattaatct tttcaatatc aggtaataat agtatattta
      901 taataagtaa tactacaatt aaaccaatcg ctacagataa tccaaaatat gagaatctaa
      961 gaatcaagta agatgctacc atacttccaa tagcccatcc aatcgaccca aaagtcttaa
     1021 taaatgacaa ataattatta atattatctc cacaacctat tatccatgta tcatataaac
     1081 tacagcaagt atttaataat cctcctgata aagcaacaag taataagtat attataaaag
     1141 ttgcagattc agtagaaaac ataataactg atgcaattcc ataaactgat aaactaatta
     1201 aaacaatttt tttcattgtt tgatacttat cagctaatac tccaaataat aattgaaata
     1261 atatattggt tattgcataa ctcgataata taattcctct ttcaaacgct gagtaaccta
     1321 attttgataa gaaaggtgtg aattttgttg aagcaaaggc aaaaataata tatgagaaaa
     1381 aatagaatat gataaattta aatttaatcg ctttattaat cataatcaat caaaattgat
     1441 aactttaata ccactatttc cttcctgatt taagtttgaa agatgatatt ttaccgtatt
     1501 aggattctct acaataacta aaggaatata taaagtattt tcaagtaact tattatcaat
     1561 ttctactaac ttttccccca tattaacttc ttgaccttgt ttaacttcta atttaaagtt
     1621 ttcttttttt gttgttgcac tgtccaatcc aatatgaata agaatttgaa catcattttg
     1681 caatttaatt cctatagcat ggttagtttg agcaataaaa cttattactc ctttagtcgg
     1741 tgatttaaga atattgtcct ttgctatcat agcaaatcca tctcccatta ccttagttga
     1801 aaatacttta tcaggaattt ctccaagatt aattattttt ccatcaatgt atgaattaat
     1861 tgtaattgct tctttttttc ttttaaagaa cattatagac actcctctac ataattaact
     1921 ttattctaat tatcattaca aataacgata ttaagcatac tgcaattgag gaaaaaagag
     1981 ccttatagct ctttccccat tgtagttctt taatactgct tatgatttgt ttaattccaa
     2041 caaatttata aatataggta aacatgataa caatagttat tgtgtaaatt tggaatatct
     2101 gccctaataa gactaaatag aaagcaatca tgttttcttt tatctcttta ttctttttta
     2161 tattgtaaat aacatatgca ctgtatactg cactaaagtt agagattaaa tttaaacttg
     2221 cattaacatc attgtttaaa agttgtgaaa atgaaatatt tgtaaataat gatgtcaatt
     2281 ctaaatacac tatatataaa acaggtaata ttagaaaaca aaccataacc actgaaagaa
     2341 atatattttc atcttttaat actgctgtga tattttttat tttatttgtt atcatgtttt
     2401 tgttctcctt atttaaaagt tggccagaaa tccttattag ccacaatcat ttcatctaag
     2461 atttcttttg ctacttttgc acttggaaca gttttactca tagtaaacga ctgccataat
     2521 ttttgataac ttttttctat ccatgcttct acagctaatt tttcagaagc aacttgttgt
     2581 tccattaaac ctttttggaa agttggaatt ttacctatag acataggttc aaccatatct
     2641 tttccaacaa ggcaaggaat ttcaaccatt gcatcatctg caaaattttc aatagctcca
     2701 ttattaggaa caatcagtaa aaatctttcc tgagtattaa atgctaatgc acaagctaat
     2761 tcaacaataa attgagaatg ctcacttgca tcaaaccatg tatcccttgc tgtgccattt
     2821 tttataattc tttcacattc ttcgaatgta tccttttctc ttctatccat aatttcattt
     2881 gctcttgtat aatttggatt agcatgttca acagtttcat cagccattaa ataatatttt
     2941 aaataagtat taggtaatgt agttggttct atttctaata agtcctttgc tgctctcata
     3001 gtttctaacc aactagattc tttgtgttga ccttgaggtg taaattcctc atatcctttt
     3061 ttagcacaat attcttgtaa tttaggcatt aaatcatttc cttctttgtc cttaatactt
     3121 gtccaccacc cgaaatgatt caatccataa tatctaacat caaagtcttt acgagaattt
     3181 aaacctaaaa ctctagcaaa tatttcctct aaacatactg gcatatcaca aatattaata
     3241 attcttgaat ttggtcttaa tacacgacat gcttctgcaa ctatagctgc tggatttgaa
     3301 taattaagca tccaagcatt tggagaatat ttttccatat aatcaatcat ttcgattatt
     3361 ggacctattg ttcttaatcc ataggcaatt ccacctgccc cacaagtttc ttgaccaaca
     3421 accccatatt ttagtggaat tttttcatct tgttcacgta aagcatataa accaacacga
     3481 atttgtgcca ttacaaaatc aatatcagta aatgcttctt ctggatttgt tgtataacta
     3541 aatttaattt ctggattttt ctctctaaca attattgcac atgcttcagc aacttttctt
     3601 tgtctctcat cattattatc atataattta attgattcaa taggaaattt agcaacactt
     3661 tcaattaaca ttgttacaat tccagcagta taagtactac ccccaccagc aattagtatc
     3721 ctctgtcttt ttctttccat ctttccttct cctttataat aaattttcaa attcttctct
     3781 tacacttggt actgaaagcc caataataat ctgaatagct tttccattat gcactaaacc
     3841 atgtgcacct actgccttaa aatcttcttc tttagaaata attgagtcat ctttcaaggt
     3901 taatctcaac ctcgtagcac agtttgtaac atctacaaca ttttctgctc caccaactaa
     3961 ttttatgtat tcagatgctt gttgagaggc tttactcaat ttatttcctt tttcatcttt
     4021 agtttctaag tattcatttt tagtatatag ttttgtttct tcactatctt cttctctacc
     4081 aggagttttc atatcaaact tcttaattaa gaaagtaaat acaaagaacc agataaatga
     4141 aaatataatc cctacaacaa cttgaacaac atataccttc cagtgataca ttccaagagg
     4201 aagccaattt aatacaaccc agttaataat tcctccacca aaatcaccaa caactcctaa
     4261 ggcaaacgaa atcgtttgca agcacgcatc taaaaatgca tgtactagga ataaaagtgg
     4321 tgctacaaat aaaaatgtaa attctaacgg ctcagtaatt ccagttaata ctgcagtaag
     4381 agtagcagga atcattaaac ctaatacttt tttctttttt tctggctttg cagttacata
     4441 gaaagcacca aatacaccta atgaaccaaa caccttcgat aatccggata atgaaaatcc
     4501 gattggatac atttccttta gagtcttagc tgaagtttga aaatcctgaa tatgagtagc
     4561 ccaatatact gatgtaccac ctggaacaac aacactatca taacaaattg gtgcatatac
     4621 aaaatgatgt aatccagttg gtattaaaat cttttgtaag aatgcataac accaaactcc
     4681 tatatttcca ctatttataa aaaacgtttg caaatgtcta ataacatttt gaatatgagg
     4741 ccaaataaaa caagttaata atgcaactgg tatcataaca aagaaacaaa ttgcaactac
     4801 aagtgatgag cctctaaata atccaataaa atctggtagt tctttatcat aaaatctatt
     4861 atgaatataa atgacaatac ctgatattaa caaagcacca accataccag tatctaatgt
     4921 tttaatacca gcaatgctta caagtccact tccagcactt atttcagctg cgaaatcaac
     4981 tccaaagctt tttccccaaa aacttaacat agaacctaca aaataattaa aagtcaaata
     5041 cgttgctaaa gcctccatac aagctcttgc ttgttgcttt tttgcaagtg ctattggtaa
     5101 agaaatagca aataataatg gtaattgatt aaataccatc caagctccac tagatattac
     5161 accccaaaat tggtaccaaa tattttctgg tgtagcaagt gaacccataa ttgactgatt
     5221 ttgaaataca attgagaatc caaccattat cccagcaaaa gcaaataata gtgttggtgt
     5281 aaacattgcc cctccaaaac gctgtatttt cttcatcata taaattactc ccctcctcat
     5341 atttttagtt tatctttggc cttagatatc tattatttta acaggttaat aaatatatac
     5401 aatctttagg gtacatttgg agcttattca cagtcaaata agtttttgca catttttatg
     5461 ttcaaattct cataaaaaaa aagaatgact acaatttgca atcaatccct tctgtaatca
     5521 ttctatgcct tttataaata ctatatttaa taaataataa ctcaatcaat ataaaatata
     5581 acattgtcaa tttataacta gggtgcattt gtaaaaatga gatattagtc gctgaaatat
     5641 aaattgattc atcacttaaa tcagtcaatg tattattttt aaactctgta attgaaatta
     5701 ttttagttcc tattaatttt aatcttctag caatattaag tgtattctca ttctcaccac
     5761 ttagggatat aataatcata acatcatttt tactgacaat attgtaaaaa gaatcatcaa
     5821 atgttcttcc ctcaaaatca tatattattt cttgacatga taagaacatt ctctttatct
     5881 gttttgcaac tacattttga atatcacctg aaccataagc gtatattgtt cttgattcat
     5941 aaagaagttt acacaatgca tcataatctt tatttttttg atcttcaaca tacttaatta
     6001 ttgaattaca tgcaatatca aatgactgat tttctatgac atgaaccttt tctgattccc
     6061 agcttaataa tactttaaac tcactgaaac cttttaaatc taatttttta acaaatcttg
     6121 taatagttgc acgagacaca ttacatttca tagcaagttc atttattgac atcttactac
     6181 aatgtttttt atttgcagtt atatatttcc atattaataa atctgtatca ttcaatttat
     6241 tataatttaa aaaaatcatt tcttctaatc tcataaacta ttaccccctt taattaaaaa
     6301 tcgtcataaa tattatacca atattcaaca ttaaattaca gcgtattctt atatttacta
     6361 tttagcccat aaaattgact ataaaaaata ctgctataat tgatgtttaa aaaaatgtag
     6421 ttttaatttt attcttttat ctaataatta atattttcaa gttctagtgc ttttcttata
     6481 caattatcat ctttaaaatc agcagtcctt ttacaatctt ttactttaaa ttctggaata
     6541 gttttaaatt cctcatcaca tattccattc ttatttaaat acatacaact tgccattcta
     6601 actattagac cactattttt taaattaaac aatacagggt ctatacaccc tccatctccg
     6661 ccagtagttt caccaactaa agtcgcaaat ttagtttctt tacaaaacat tgcaaatgac
     6721 tctgatgatg aatatatttt tctatcaaca agtaagtata tattaccctt aaattttgaa
     6781 tcatctgtag attttatagt ataggaagta tcttcaaaat cattaaaatc ttttataatt
     6841 tctttaggtg cattttcctt tacacttgtt ggtaaatttt ctacaggatt taattttata
     6901 tttcttgcat ttgtatattg ttttactatt tcattattat ttctataaat tctataacca
     6961 tttattttga catcattttt tatgagttta gatacgattc cctgccaata actatcactt
     7021 ccacctaaat tacctcttat atcaataatt aaagctttat gtttttctaa agtgtcaata
     7081 taatctccaa ttatttttaa atcattattt atagagccat tctttgatga cattgatggt
     7141 aaatacatat atccaatctg acccttaata acatccttta aaattaattc tttttttaca
     7201 aaaatatcat ctggcatttt tattttaaga ttcatagagt catatctatc tacaactttt
     7261 ttatcattaa gaaaatcata ccaatcatta ttagagtatg atttcttaaa aagttcatat
     7321 cttttcttat tatctattac ttctgtgtgt ttattattta aatcagataa tatagatgac
     7381 atttcttcta taaattcttc atcattttca gtgtttttta ttcgttttgt atattcatcc
     7441 ttatttgcta accaatcaat attattaagc ctcttattta cacctagata tggatatcct
     7501 gtctttacaa cattatacac ataattaaag tcatccacct tttcctcttc agacaactga
     7561 ttcttttgag aataagtaga attacctaat aagattataa atgctaaaat aattactaaa
     7621 aataatactt tctttttcat gtaattctca tccactttca gattttatat tttaatacat
     7681 tgtatcatta ttttattatc acctaaacag ttaaaagaaa ttcttgaaga tatattccac
     7741 tattattctc tttaaaaatt tttatttgta ttttcaaaat tatttcatga aagttataaa
     7801 ataacaatta tattcaaata tctattttac tgctatatcc tgaaggtaaa ttcttatcag
     7861 tgatatacta aaaaagatat gctaaaaaat ttatccatta taatgactta aatttagata
     7921 ctttactgat ttttatttat tagttgagaa agatattgat aattaaaaat attgataact
     7981 atagaaatga ttatttttta tagaaatttt aaggatataa actaattata cttaagtcta
     8041 tatccttaat ttatcatgat tatgagaatt tttacaaata cttatctttg tccgttttag
     8101 aataaaaaca agaacatatc ctgttatttt attcaaacat ccaaatttaa ttactacaca
     8161 attacttatt agaaattgta tctacttcat atatatatct gttaagtata gcttctagca
     8221 tttcttgtct tccagactta ttctttataa ctggcatttg cagtgcataa gattctaact
     8281 ctttaaatcc aaccttacct tctactatat ccttacctat accttcacta aaacttgcat
     8341 atctttcttt agtaaagttt tcaaatacct catcttctaa taatttatga gctattaata
     8401 atccctttgc aaatgtatcc attcctgcaa tataagctag gaataagtct tctacctcaa
     8461 aagatgctct tcttacttta gagtcaaagt taaatcctcc tggtgctatt ccaccttgct
     8521 ttaacacttc atacatagca agtgttgcat catatatatt tgttggaaat tggtctgtat
     8581 cccaacctaa taataggtct ccttgatttg catctatact acctaaaaca ttgtttattc
     8641 ttgctatatt taattcatgt tggaaagtat gtcctgcaag tgttgcatgg tttgcttcta
     8701 tattcatttt gaagtattta tccagattat actttcttaa aaatcctaaa acagtagcag
     8761 tatcaaaatc gtattgatgt ttagtaggct cttttggctt aggctctatt aagaattggc
     8821 cagtgaatcc tatttcctta gcataatcta cagccatttg taagaatctt gcaaagttat
     8881 ccatttcaag ttctgtatta gtgttaagta aagtttcata accttctctt ccaccccaga
     8941 atacaaaatt ttctcctcct aagtacttag ttatttccat agctttttta acctgagctg
     9001 ctgcatatgc atatacatct gcattacatg ttgtagatgc accatgaaca aatcttggat
     9061 ttccaaacat attggcagtt ccccataata actttatacc tgtcttttcc atattaactt
     9121 ttatatactc aactatttca tctaatatct tatttgtctc ttctaaatct cttccttctg
     9181 gtgctatatc tctgtcatga aaacagaaat actcaattcc catcttagac ataaattcaa
     9241 atcctgcatc aactttaatc tttgctatct caattgggtc tgttatatta ttccaaggtc
     9301 tctctactgt gcctactcca aatgggtcat taccctctcc acataaagta tgccaatagc
     9361 tcattgcaaa tcttaagtgt tctttcatag tcttattacc taccacttgt tcaggattgt
     9421 agtatctaaa tgctaattca ttgtcagatt ttactccttc aaattttatc tgtcctattc
     9481 ctttaaatat ttcactcatt tcatgtcctc ctaatatttt acacatataa tatatgtagt
     9541 atgttttctt aatttaaaac tattttctat ctttattttt ctttttaagc taatttaatt
     9601 atttattttt gcattaacta cttcatctaa taacttaaag tcatctttca aagatttgta
     9661 tattctttta tacaatctat gatatatatt gtatgtatct acattttcac ttattggttc
     9721 taatttagtt gaagttttta ttatagcatc acatgctttt tgtatatttt catatattcc
     9781 agctcctact aatgcaagaa ttgcaactcc aagtgctggt ccttcacttg aatttatagt
     9841 atatacatct tgattaaaca tatctgcttg catctgtctc catactttac tttttccacc
     9901 tccacctgag gctcttactt cattaacgtc tatattaaga ttctctatta tatccataca
     9961 gtctttaaga ctatatgaaa caccttccat tattgacctt gcaatttctt ttttagaatg
    10021 gattggagat aatccaaaga acacacctct tgcataaggg tcaagatgag gagttctttc
    10081 tcccatcata tatggtaagt aaagcaatcc attacatcct gttggtactt gacttacttg
    10141 attatttata atctcatata catcttcacc taaagaattt gaaacttcca cttcactttg
    10201 acagaaatta tctttaaacc attttaatga caagccagct ccttgagtaa ctcccataac
    10261 atgccatgta tttggtattg catgacagaa agtatgaact ctaccttctt tatcaatttt
    10321 tggctctttt gtataagcaa atactacacc tgatgtacct atagtagatg aaactactcc
    10381 atctttaact attccatttc ctatagctcc tgctgcttgg tctccagctc ctcctaccac
    10441 tattgttcct tctttaagcc ctgtcaaact tgctacatct ctagtcacat aacctgtaat
    10501 ctcttgtgat tcataaactt tacctaaaag atttttatct atatttaact tttctagtac
    10561 ttcatcgctc caatctcttt ttcttatatc gagcaactgc ataccacttg catctgatac
    10621 ctctgtagca tattcacctg tcaatttgta tcttatataa tcttttggaa gaagtatttt
    10681 attagtattt ttatatatat ctggttcatt gtttctaacc cataatatct ttgatgctgt
    10741 aaatcctgta agtgctggat tagcagttat ttcaatcagt ctttcttcac ctactaaatc
    10801 agttatctcc tcacactctt ttactgttcg ttggtcacac catattatag agtttctcaa
    10861 tgttttacct tcattgtcca gcataactag accatgcatc tgtcctgata atccaattcc
    10921 ttttatacat tcactgctta tatttgaact ttgaactact tctcttatag attcgactac
    10981 agctttccac caatcatttg catcctgctc tgcccaacct gatttctctt gtataagagg
    11041 atattcatat gtacaacttt ttatagtatt tcctagttta tcaaataaaa ctgttttagt
    11101 acctgatgta ccaatatcca cacctaatac atactccaac ttcatccctc cttgaatgcc
    11161 acttcataac tatcgttttc ctatcctaat ttttttatat tttaggtata ttttacttgc
    11221 tttatttttg ttagtatatt aaactaactt atgaactaat aataaaatat ttaattatct
    11281 ttgtcaatgc aaaataacct tttatttttg tgtaaaaagt attacaatat tattttaagg
    11341 aggaatatca aattggttac tgataaatac actattcgag aaatgaatga aagattggta
    11401 cttgaacaaa ttataaaaaa tggtcctatt tctagggcaa gtatagcttc tactatagga
    11461 ttgaataaag caactatatc cgctattacc aaaaaactta ttgatgaatc tctagttcat
    11521 gaaatcggaa ttggaaatag tactcatagt ggcggaagaa aacccatatt attagtattt
    11581 aataaatgtg cagggatttc tttaagtatg gacattggat acgactatat attttcttct
    11641 ctatcttact tagatggaac tattataaat tctaagaaat taacagatat acaagtaagt
    11701 aaagacaatg ttatacaatt gatagatgaa attataaata gttataacat atccaaaata
    11761 gacactcctt ataaggtaat tggtcttact ttggctatac atgggattac ttgtgaaaat
    11821 aaagtattgt ttactccata ttacaatctt aatgagattg acttatatag catccttagc
    11881 aaaaagtatg actttcctat tcatatagaa aatgaagcaa acttaacagc tttagctgag
    11941 aatacttttt caactgtaca taactcacta cttagtctca gtattcacag tggatttggt
    12001 tcaggcatta taataaataa taaattatat agtggcagaa atggtatgag tggagaaatt
    12061 ggtcacacta tcatcatgcc taacggtaaa ctatgtcctt gtggaaatcg tggctgttta
    12121 gaacagtatt gttcagaaaa aaaggtattt gaacagcttt cttctttaga aaatattcct
    12181 aaaatagatt ctgatatagt aaagcaacta tattatgaag ataaccataa tgccaaaaaa
    12241 gttattcatg agttttgtag ttacttaaca atagctataa ataatgctat tacaacttat
    12301 gctcctgaaa taatatattt aaatagccaa ataattagtg atatacctga gatattacag
    12361 attacaaaag atatgttagt tagctctttt aacaaaggaa taaatataga aatttcatca
    12421 ttagggtctg aggcatctct atatggtggc tctgctgtaa atatcaagag ctttttgaat
    12481 atacaaaatt taactttaat taatgaaata taagggttat gactatatac agccataacc
    12541 ctttaaatta tacattctaa aattagattt attatatagt ttatgcaaga ttagctatat
    12601 tttttaaaaa ttgtatatca attaagtatt aacataagta cttcgtttta aatattaata
    12661 taatcttcct actcatcatc agataataaa cttgcatttt gttcaaccat agaaatatta
    12721 tctttaccta ttttctctaa ttttgctgcc aattcctttg tatctaaaaa agctgattca
    12781 ataaccatac ctaaatttag ccctgaaata attttaattc gactgtcatt attggctact
    12841 aataaagcag cattgcatgg agttccacct agtaaatctg ccattataat tatttctgaa
    12901 ctttccttgt acacttctaa agcttttttt aatttttcta ttgttccttc tattccatca
    12961 tcttgtttca tatttacagt aggataatct atagaatccc ctattatcat ttttgcagaa
    13021 tttaagactt cttcagccat attgccatga ctcatcaaaa taatactatt caatttaata
    13081 cacctcttta aatctataag atgtctacaa gataagtttt cttatcatca ggcgtcatta
    13141 tagttgtaat ttcaattcct tcatctaaaa gtcttttaaa tgcttctttc tcttcttcag
    13201 taacactgat attaggtctt agaactgttg tatcttttct acttgacata tttcctacat
    13261 ttatattatg tattttaaat cctgcctcta caaatggaat aaggtccaca ggagacttaa
    13321 caattaataa tacattttgt ccttcatact ttcctgcagt aatatttttt atagcagtct
    13381 cttctgtaat tatagatgac gctatacctg caggtgtagc cattcttaaa acttgttttt
    13441 gaacagaatt gttagctact gcatcattta ctaccattaa tcttgtaaca cccaatttat
    13501 tactccacat agttgcaact tgaccatgga ttaaacggtc atctatacga atatttttaa
    13561 tacctttcat ttccatatct aatatcatcc tttccttatt ttaaaatacc taatgcatat
    13621 aaaattattg aaacaaccat tactcctaaa attaagtata taggttttat attcttttta
    13681 agagcccaat aaacaatcac aactagaatt gcaggaacta acccaggcat aatttggtct
    13741 aatatttctt gacctttcat tgtaaaatca ccttgttgaa agttcaaagc aacattagct
    13801 tttacaactg aaggtattaa tgcacctaca accattaaac ctaaaataga tgtactctca
    13861 gttaaaatct ttaaactttt ttcaattgaa gatattagct tagtacctga tgtataacca
    13921 gcattaaata gtggtatact taataatttc aatgctacac tcactacaat ccacagtaag
    13981 attccaaatg gacttccatc tatcgccata ttagctgcta tagctccaaa aattgtccac
    14041 ggaataacga caaataaact atctcctaaa cctgctactg gtcccatcaa gcctgtttta
    14101 attgaagcaa cagcctcttc agtctcttca cttgataact cctccattgc tacattaata
    14161 cccaaaatat aaggggcaac ccaaggatta gtgttaaaaa attgtaaatg atttaataca
    14221 gcactttgta acttttctgg attatctttg tatactactt ttaaaaaagg tagtactgca
    14281 taacagtatg ccaaggcctg catcttctca taatttgaag aaacagaact agtaaaaaac
    14341 cagcgccata agacactttt tttcaccttt tcatttgatt tatttaatga taccttatca
    14401 ctcatcttcg tccatacctc ctactacagt atattgttgt tcttgatttt ccaaattctt
    14461 tttgtaaatt ataagtgcaa ttgctccacc aattaaagct acacctaata atggtacttt
    14521 catatatact gctaaaacaa aaccaattac taagtaacta aaatactcct tagcaggaag
    14581 atatctaagt aataatccta tccctactgc tggaagtagt cctccagcta ctgttaaacc
    14641 acctgttaac cattcaggtg tatatttcaa aatggtatta attaaagaag gtccaaatat
    14701 tacagataga gcaactggaa tacctgttgt agctgctgtt aatagtactc ctaacatttg
    14761 catataggtt atatttttat aatttccttt tttagctcca tcttctgctt tatgaactag
    14821 ccatatacca atagtatttc taagaacatc taattgtacc atcaataaag caactggaat
    14881 acctatagag attcctacag atgcttcttg cttagtcgta atagttataa atgtggctac
    14941 tatacttgct gtttgataat caggtattga tgctccacca aagttactaa tacctaatga
    15001 taatagctgt aatgtacctc caatatataa ccctgtattt atatctccta agataagacc
    15061 agtaataaaa cctgctgtta ctggttgata tgttccaaac attgttgaat ttttttcata
    15121 gtttataaaa aatccatata gtacgattaa taataattgc cataattgtg gctccattat
    15181 gatttcacct ctcccaaaat attttttagt tctttaaaat tataactgga atcttgcttt
    15241 aggaaaatag gaatttcttc cagtgggcat tcaacttcat aagttttccc accttcataa
    15301 ctaactccac taaatatatt ttcccatgta tgtccttttg gtaaatatac ttttctactt
    15361 ctatctttat aattcattat tggagctacc aaaatttcat ctccaagcat atatgtatta
    15421 tccacctccc aagttttatc atcttcagga aattcataaa ataaagttct cataactggt
    15481 gttccatctt catgcgcttc tttcatcagt ttttttaaat aagtttttaa gctctctcta
    15541 atttttatga attttgtaag aattacttca acttcttcac cataagacca tatttcatta
    15601 ggagctccag ttaccattga gcctccacct ttatttgata atggtttact atgaggcaat
    15661 ctatctccat gcattctcaa aattggtgaa aaagtagcat attggaacca tcttaccata
    15721 agttctctaa attctgggtc tttaggattt cctccatgga aacctccaat atcagtagtc
    15781 caccatggta tacctgccag tcccatattt aaccctgtat ttacttgatt attaaaagct
    15841 tcaaaactag aatcaatgtc accagaccat actaaagctc catacttttg agctcctgcc
    15901 caagctcctc ttacaagagt tacaacagac tctatgtcat tatgtaaacc atcataaatc
    15961 atttttaaat aatcaatagg ataaatatta ccacaactta aaacatttcc ttttttatat
    16021 ctatagttat caaaatcata cacagaatag ccaggttcag ctacatctaa ccaataatag
    16081 tcaatcccaa gttgtttata atttttatct attctatccc aaacatattc tcttgcattt
    16141 tcatttgtca tatctacaaa gactgtattt ccttgaattt gcattgtcat tctaacacca
    16201 cgattaacat tgactaaata gccattttct aaataatcat tgtagttttc tgcatcactt
    16261 tgaactgtag gccatacaga tactattggt tctactgaat actcttcttt caatttttta
    16321 actaattctt taggattttt ccaataatct aagtcaaatt tatattcacc ttgcttaggc
    16381 caatgaaaat agtcaattgc aattgatgaa agcttaattc ctcttttaga atattccttc
    16441 acaacatcta aaacttcttc tgaagttcta tatcttagtt tactttgcca tagtcctaaa
    16501 aggttttcag gcatcatagg aacagttcca gtaacttgag aataattttt atttaactct
    16561 tttgggcttt ctccacaagt aatccaataa tctataaaat ttgtagaaaa catcttccat
    16621 tctgtcatat ttttagcaaa agatactttt ccaattcccg gattattcca taaaagtcca
    16681 taacctagac tagaaatata aaaaggaact gatatttgag aatttctttg ggctaactcc
    16741 aaaacagtat tctttaaatc taaaaattta tgttgatatt gtcccattcc aaaaatcttt
    16801 tcagaaggct cagattcaaa tctagtagtt acttcaaatt ctccactata gcttggtcga
    16861 tattctcttg attttaactt tagagtagag ttaaagtctt tggtaatctc aattgtccct
    16921 acatcttctc caccatcatc atgttttaca gctcttaatc gaatatattc tttcaataat
    16981 atttcatttt tatcattata aaaagtaatt ctatctctat ggtctaagac agcttttatc
    17041 tttccatttt taatgattgc acttccatct tcatttttat taattgtaat atcatcttta
    17101 tttaacttag gtttttcgtt aagagcatag ttttcatcaa caaaattttg gtctacaaac
    17161 gacctaatac gtaaagagtt ttttccccat gcttctattc gcaatagttc attgtcaaat
    17221 cttttttcaa tatagtcttc agatattttt atcacggcta cctcctaaat caatggtata
    17281 atattctatc tttgtgtagc ttaagttaaa taatgtcgtt tagtatcgtt atttataaat
    17341 taggttttat atataattca tttgtacatt aaactaactt accaataata tactttattt
    17401 gactttgttt gtcaatcgct ttccggattt tagtaaaatt ttctaatata ttgctggaaa
    17461 gtcgttctta atatctttta tttatacttt taatatctgt gatgatacct atatacatct
    17521 agttttttta aaacacatac aggaataaca tttgcctatt atgtagataa tatcggactt
    17581 gaaaatatgt atagtgacct tataaataca gataataata tattagatat tgttcaaaac
    17641 aatggatttt ataattataa ataatttatt aaattattta agaaaatata caattgtata
    17701 ccaagtcaaa aacgacaaca aataaataaa actaaaaaag atgttgtctc aaaatataga
    17761 taaatttatt tttcattgct aaaatgatta aaatatattt gatttaatat acttgattta
    17821 atataaaaaa agagtgtctc ataaactaaa aagttcactt ttagacactc ctttatatat
    17881 attatctact tcttaattca tttattacct ctctacattt tctttcaact agtggataca
    17941 tctttataag tactaattac tccacttaaa aatgattcag gtactgtcca tcagtcatat
    18001 ttttctgcca aatataatgg tgtttcataa tgagacaata aatatttata tctctactta
    18061 tcttctctaa gctcgtcaaa tccaactata ggtatattta aattatattc tttaagtagc
    18121 ttttctagct cttctataaa aatacctttc ccatccacca tttgtatatc atttatttta
    18181 tccatcaatt cattgcaacc acttaactca ccaaaccaac gtttagaact acatgtctta
    18241 ttataaccac aacttggact gccatctatt gcaatgatac tttttatatc ataatcattt
    18301 tttaaatatt catcaaactg ccttacatga ggtattaaca tttgcctaca ttgttctcta
    18361 aaaaacaaat tgtcaaactg ttcttttaca tgtccccacc tatttattcc atacataatc
    18421 atttctgggc atggtagttg aattattcca taccctttat ttattaaatc tatcgctata
    18481 ttttgtgctc ccttaaattc tgacaatccc tctactttag aattacaatt taatatacaa
    18541 tgacatacta ctacaatctc tctatttctc ttcataataa tctccttagt tattcttaat
    18601 tttaatgata ctacatattt tgataattat attatttatt tgttctatat ttccaatatt
    18661 ctatatagaa atatacaatt agtaatcttt tataatctat actatgataa atgtatatat
    18721 ttttttagga ggtattataa ttggatacta aaaaagtcac attttcttca atgtgcatag
    18781 ttattaatat tgtcttaggt atggttatat ctatgataaa tataccatta ttatttttag
    18841 atacaattgg tactgtactt ggggctgtcg tattaggtcc tttttggagt gctcttattg
    18901 gtgggtgtac aaacttagtt ttaggtgtta tatcaggtcc tacaaatata ccttttgccc
    18961 ttgtaaatat tgttcttggt cttattgttg gatatatttc taagaaaaaa ggttttggtt
    19021 ataaagaagc tattattaca ggagtaattt tatctattgt ttgtccttta attggtactc
    19081 ctatttcagt tttattgttt ggtggtttaa gtggaagtgg tgctgattta ttggttggtt
    19141 ttttagttca gtctggtcag aagatattta ctgctgcgtt ctttccaagg attcttagta
    19201 atatagtaga caaacctttg tcttgtatta tggtggtata ttttataagt aaaatgccta
    19261 aaggttttat aaaacaatat agtaaaaata cttctagttc atattaataa atcatttatt
    19321 atgtaagatt tattactctt taaaatgcta tatactcatt tttatataac atttttatta
    19381 ataatttaat tagatagtat ttgtattatt ttaattaaac gtaacctctt gatataaatt
    19441 tgagctataa atctatatca agaggtgcta ttttattttt aatataatta atattctatt
    19501 acgcaaaaaa tacatatatt tcattatttt atggaaaata ttacttcatt taactctata
    19561 tcaaactcat taagtaaaaa tctaattata tttaatttag cctctgtatt taaatttgtt
    19621 tctaaatata tattttctga tattttaata ccttttctta atttatatgc atctctagac
    19681 ttaatattat ctataaaatc tcttttataa gtcttgtcta caatactgtt aaaccttaca
    19741 gaatccaaat catataaagt aagagcaact tgttcataaa attctgtcca atttttagcc
    19801 ttatatgact ctcctaatat actaaatgat actatacttt catttgtaaa attaacatca
    19861 tcatcctcta acgtaaatat attttcactg ttacttggag gttcatatgt aacacttgga
    19921 tatttccaaa tttctacagc tctatctagt aatatcttag ttctattttt tatttcttct
    19981 tcattccatt tatctataga tgaaatatat ttatttagat aaagcctact atctttaaat
    20041 ccatcttcca tttctttctt ttcttcaaat gttttattac ttagttttga attatatcct
    20101 gtcaaagtta aatttccaat tgtatgtaaa tatttatcat gtatctcctt atagttatct
    20161 cctagtgatt ccttccattt atttgttaat gtctgtggca ttatatgctc tatatttagc
    20221 atattattat tgattaaatt ttctaaatca acaatttctt tattattata attctctaac
    20281 ctctcaagta tatataactt attctttgac ttagtattat atatatcttt agtttcaaaa
    20341 gcatttgaaa attcactgtc agtaggaaat ctttgagatg atttcttatt tataaaaata
    20401 tatcttaata tattagaata gttttcttta taatcactaa attttttaat ttcccttcct
    20461 aagttcataa atactttatt cagtgcatta ggaggtacat cacatactat tcttcttaat
    20521 ataaaacatt ctactaaatt aagggattct acaagtactt ttttatttat tataccttca
    20581 ttataatcat caaataattc taatataaac ggatatgata caaatatttc aagtttgttt
    20641 atccttttca aaactttgtt tacatcatta tcatcagtac atgaataaga tatctctcta
    20701 taatagttag aaaatttaag taaatctttt aataaaattt ctatatctat accattatct
    20761 gatacatacc ttttaaaact aaaatatact ttatttttat tcggtatact tctctccttt
    20821 atagtcaaat agtctcttat aaaactactt acgttgctac ttgtattttt ttcaatttta
    20881 taccaataat tattataaaa ttcctcttgt aacttagagc ttctacccat taacacaaag
    20941 tttcttactc tatcagcttc acttaaatct aagccagttg aatttagact ttcaaagatt
    21001 aattgagggt catcttcacc attttttaac tctatttcta ctatagttaa tttctgtata
    21061 gcatcaaaca aatcatctat tgatatatta tcttctttta ttctattata aaaatataaa
    21121 taatttgaaa ctatattaga atttctatct gtattcattt cttcttcaaa tagttcatag
    21181 tacgcttttc tatcttctgc tattggtttt aactttattt ttccatcttt atctcttgag
    21241 tgcttgttta taagataaca ctccttaatc tgttcttctg ttgtaataat tccttttgat
    21301 tccccaaact cttttattat ttgacacatg gcaatcaata atattgacac agtagtcact
    21361 ctttgttgtc catctattat taaatattct tttcccatac tatatataga tacaactgac
    21421 cctaagaaat gagttctaaa tccagaatct attatatcct ctaaatcatc aaacaatctt
    21481 ttacattgtt ctttcttcca gttataattt ctttgatata caggtactac aaaacttttg
    21541 tttgacccct ctaaataact aagaaattca atttctcctg ctttcatatt aactccccct
    21601 ataagttaaa taaattccat tcataactcc atgtatctat atattatatc aaaattttga
    21661 ctcataaatg tatatgaaag ccttattata taccttttta tacctgtttt tattttatta
    21721 aagtaaatac atgattattc tataaaatat acaaatactt aattttaaaa attattattt
    21781 aatcttcttc atgagtaatt catagttatt tatcaattaa aaagagatat tgcataatta
    21841 ttcaatacct ctctttgtat atttacatta tccatatcta gttatctatt tcaacccaat
    21901 attagactac ctactaataa atttattctc tacatcatta acaataattt tgcactaaat
    21961 aacatcatta gcctatctct gatgcatttt ctttaatttt atttatagtt ttaatcaatt
    22021 tatttctctc ttcaatatga ttttcaaata aatcaattat acttccaaca gttctaaatg
    22081 ggtcttccat caacactttg ttatcctcta taaatccatt cttgactaca taatcgacta
    22141 taagtttaac aaaatgtatt tgcttagtat taaagctctt attatttaaa aactctgaaa
    22201 aagcttcatt tgcagcttct ctatccaatc ccactagtct tctcactaat tggcttactg
    22261 gagtatctcc aaactccttc ttataatcat cacaattacc taactgtttt aagagtattt
    22321 cctccaacgt ttcaacatct tgctttgtta tctttttatt atttcttaat ttaaatattg
    22381 ctaattcatc tttatggcta tttaaataat actctacctt ctttttataa ttcttaagat
    22441 tgtttgcatt atatacagaa tcatttctat cttctgctac aatcatatct tcaaaacttg
    22501 tataatatat cttttgacta gacttttcaa gatacttaat aagctctctt aatgatatac
    22561 gtacttcttc tacctcaaat atatctgaat cttcccaaaa atcctctgtc attgcttttt
    22621 caatagtata tttttgttgc tgaatctgtg gtatagtccc aagttttgaa agtttttctg
    22681 ctgtagccat tacatgcctt atacctttac ttgcattatt attttgtaag tatgcaagtt
    22741 gtatattata cataactaca tcaaatcttt tagccaattc atcatcacta tatgaagtta
    22801 tgagtggtga tatatattct cttatctcat tttgtgctac tgctccaata ttgctccaaa
    22861 cattttcatt tttatactta tgtacataac ttaaattcat cctaactata taactatcct
    22921 catttaaagc ttttacagaa gttataagtt cttctaacaa ttcttttcta agttctgcat
    22981 actcaccttc tatatattta atatcttgaa gttctttaac catacttacc tttatattaa
    23041 ataatttttc agtaagtgtt tctgttttat ttccctcaaa tcctttagga ttaaatttaa
    23101 aaaattcaaa attattacaa aaatcaaata ttaagaatct ttccttatcc atatcaacac
    23161 ctaataaatc tggacataat ctagttcctc tacctatcat ttgccaaaac ttagtcttac
    23221 ttctcacttt cttgaaaaaa acaagattta gtatttcagg tatgtcaatt cctgtatcaa
    23281 gcatatctac tgaaactgct atttgaggta atttattctt atcagaaaaa tcatctatta
    23341 tagaatctac ataatttata ctatagtcaa ctgcttttac aaagttccca ccatactttg
    23401 gatacagttt attaaatctt tcaactattg ccctagcatg ctttgtattc tttgcaaaaa
    23461 ttatagtctt accaatcttt tcttctcctt ctattttcaa cccctctgtc attagcttat
    23521 ttaaaactaa atctattgtg tcagaattaa atagccactc atttactgca ttattcccta
    23581 tttcgtctcc aatactctca tcatcattaa atgtattttc atattcttcc ttctcttcat
    23641 cagaaagctc atcatactta attccatctt ccataatctt agtcttaaac tcaatactag
    23701 tataatctac taaatatcca tcctcgactg ccttattata ctcataagca tatgtaggta
    23761 ctccattttc catgtcaaaa actgaataag tatttttatc tatctcatcc tttggtgtag
    23821 cagtaagacc cattaagtaa gaatcaaaat aatcaaagat tgacttatac tttttataaa
    23881 tacttctatg cgattcatct attataatta aatcaaaatg accaggtgta aacaatctct
    23941 ttccatcctt agacttcgta tcatcaattg cattcatcat tgttggatat gtagaaaata
    24001 tcatcctagc atcttctggg ctgtctttgc tatccaataa attacataac gccaagttag
    24061 gtaatagctt agtaaaactt tttttagctt gctttaccaa tgcttttcta tctgctagaa
    24121 ataatatatt tttaatccaa ttatgtcttg aaagtacatc aactatagat atagcaattc
    24181 ttgtttttcc tgtaccagta gcacatacca aaagagtttt gcgttgctta ttttcaagag
    24241 cctcacatac agccctaata gcttcttttt gataatatct attggatatt tcatcattta
    24301 ttgttacaga acttaaagac ttcttactct ttcttctatc tatcataagt tgtaattctg
    24361 attttttata aaatccataa actttcctat ctgaatagtc atcccaaata tacatatcaa
    24421 aaccattagt caaaaatatt accggtcttt gactatatct cttttccaaa caatctgcat
    24481 ataatttagc ttgttgttga ccaattttcg ggtctttact cgttcttttc gcctcaacta
    24541 ctgctaatgg cttaccattt tcaccataaa gaacataatc tacatatccc acaccacttt
    24601 cattaggcat accttgtact tctatttctt cccatatatc ttttccaaat tcccaacctg
    24661 caagctttaa ttctatattt atatatcttt ttcttgtctc aaattcgctt acttcgtcta
    24721 tcttgaaatc atagtttaca gtattaactt ttctcttttc agttagtgac tttcttaatt
    24781 cctcattttc ttttattact tcttcaagct ttttatcttt tgaacttaat ctctcataaa
    24841 gatttttaag ttcgtctggt ctcgtccttt tctcttcccc atgaagtaat aaatcttcat
    24901 taaagtcttc tgctgtatat tcatctgaat aacaatagtc tatccaacta acaaattgat
    24961 gcaaattgtt aagtgaaagt attgcttctc ctctctctat gttcgcacta gtatgtacag
    25021 ataaattacc taatttaact atatatttta ataaaggtaa catatcatag tctataagtt
    25081 ctataaaact attattatga atcaacgtac taagattatc ttgataaggc aatactaaat
    25141 cactatcatt agcatatagc cattttactg caagctctaa agctcttctt gttatagttg
    25201 cacaagtaga tgggctaact agtatacttt tttctgcttc taagcaagca gtattaaaac
    25261 tattgaaatt tttcttcttt tgtaaaaaat caaaattacc caaggctttt atcccccttt
    25321 tgtcccttag ttaaaataaa tctctctaaa aactatttct tacagctgtt tcttatacta
    25381 acaaatactt cttcattttc tgtaaacaat tcgtacatat cttcaaactg tggtatatca
    25441 tatccatgag aatcatcatt tctcaatttt ctaagtgttt ctataactat agaagaattt
    25501 ttaggtaata aattgtgata ctcacaagct aaaaggtagt cataaaagtt tttagatttt
    25561 atgtttaaat caattgattt ataatacaac attgcttttg ttaattctag aaatgatacc
    25621 atatagcttt taaagccttc ttttatgtat ctagcccata actcaggcat ttcttcctta
    25681 tcatataaga ttttgaagtt ttgcaggtca tacaagcaag aaccaaaatc cctatttact
    25741 tcttctattg agttccaaga taatttgttt ctaattacca tacatgtccc tccaatctaa
    25801 gatatctatt acatcactgt tttcaaaata gaatttattt atataatcct taaaatcttt
    25861 agatttataa ataacttcac cttctaaaat agctttttta agtgctattg tataattatc
    25921 tgtaacaatt tttaggtcta catcaatgtc taatatattt cttagagctt ctgtcttagt
    25981 tgcaagttct gtaattggta cttttttgat gggaatccaa gctatgtcta tatcactttc
    26041 tgatgtatgt ttatctgttc cataactacc aaatattatg attgctagag tattttcttt
    26101 tggaaataca tttattattg agtttttaat ctcatttggt atatttctca tttaatcacc
    26161 tcttgtttat taggtaatat tgcttaattg aatttatatc cataatcttt taatctattt
    26221 atacatattt ctctttcttc atcagtaaac aactctttat acttttcttt taatactaat
    26281 acttctaatg ataaatctaa tctcttacac tcccatagcc ttgtaaatcc ttcagtagct
    26341 ccttctttat tgattaattc tttagcagct aataaggctc ctttgttatt tatcagttgt
    26401 aaaaatcttg ttggcttata gttacattgt aaatcagctt ctttatagat atttaccatg
    26461 ttatggtata aatctagctc tatttgattc atagatttta ttcccccatt ttaataattg
    26521 tattttagtt gaataactat cctttaaaag ctttttgcat taatgagtta aagttgtctt
    26581 ctagttcttt tagacttgtt tttattccta ctttcaattt gtctacttga ttaacaaact
    26641 cttcaaactt attttgaagt tctattgatg gtactggtat taatattttt tgaagttctt
    26701 tgcttctaat tccttgtgca gagctaccag ttttatattt atctatttct accctaaaag
    26761 cttttgtttg catatattgt gctaaaaaag cattatttaa aattttttta tctccctgaa
    26821 ttgttataat cctttgaccc atagcaaact tttttaaatc ctttggtatc ctacatacat
    26881 ttccaaatgt atgaccttct gtaacaaaaa gtacatctcc agctactgga aaacctcttt
    26941 tcatccaaga attataggtg ttttcagata tatattcatt aatatattta aatacaccat
    27001 tccctacaga ttttgcattt attattctaa ttccattctc tgaaagaatt ggagttttac
    27061 cacgataatc aataaaattt gtacaatctt tcaataatac aaacttttgt tccttaaaat
    27121 ttccaaacat ttcaataaat cttgatttaa ctaattcatc caatgcttct atttgctctt
    27181 ttcttttatc tattaactct tgagctttat ctaaaacttt tgatatatct ttttgagctt
    27241 ccatttcagg taaatctact tttaaatttt ttaaatcatt aactgaaaaa cttgcttgat
    27301 taactgattt ttttattatc cttggtaact gtcttctaaa ttcattacta ttaaaaaaat
    27361 aatttaaata ctttggataa caaacttctt tatctggtcg taaacataaa agattcattc
    27421 catgtataat ttttttattt atatcttcat atattgcact tttccctaaa tgtttttcac
    27481 tattaatatg tgacattagt atatctccat ttttcaataa atagtcttct aattttccta
    27541 actcttttat gtcagcatat cccattttat tagtatcaat ataagagttt gctatagttt
    27601 ctattcttgt aattggatat ccaaattttg tatcaaattg tttaatacta gccccatttc
    27661 taataaattc aaaaacttca ttcaatctat attccatact ctacacctca agcattcttt
    27721 ctaattcctc taatccatct acgatttcct tctctaactc cctaactcta cctataataa
    27781 cactaggagc atcataaact acttcctcat acactacctc tttatactta ttaatagata
    27841 aatcataccc attctctctt atctcttcca catcaacaaa aaagctttgc tctgttcttt
    27901 ttctatctac ttcaccatca agattatcaa atctcttaat aatatcctct atatcactat
    27961 cctttatctc atttctctta tcatccaaag aataaccatc agctttcata tcatagaacc
    28021 ataccttatc agttccacct gttcctgttt tagtaaatat cattatagct gtagatactc
    28081 ctgcataagg cttaaacact ccacttggca ttgatattat agcttccaat ttatgattat
    28141 caactatttc ttttcttatc gatttatgtc cacctgttga accaaacaat actccatctg
    28201 gcactataca tgcgcatctt ccaccaattt ttaaaactct taaaaaaagt gccaagaata
    28261 ataactctgt tttctttgtc ttagtcactt ttaataaatc tgctgacact gcttcataat
    28321 ctaaacttcc cttaaaagga ggatttgcta acaccaatgt aaacttatct ttatctgtat
    28381 taacctccga taaagaatcc ttatactcta tattaggatt gtcaacgcca tgcaacatca
    28441 tattcatagc acctattcta agcatagttc tatccatatc aaatccatag aacataccat
    28501 tattaaaatg ctccttcagc ccttgcacta agaaaagact tgaatgatta tcccttaagt
    28561 attgttgtga tgatactaaa aaacctgccg aacctgctgc cgggtctact ataatatctt
    28621 ctggtgttgg tttaataagt cttactatca tatctattat gtgtcttgga gtcctaaatt
    28681 gaccattagt acctgctgta gccactttgg ataataaata ctcatacaaa tctccctttg
    28741 tatctctatc cttacttaat tctaaattac taataccatc aactatttta gataacataa
    28801 gaggcgtagg aattttaaat attgcatctc ccatgtactt tgcataagct gattctttat
    28861 ttccatgtaa tttttttatg aaagggaaca cttcattttg tactatttca tacatttttt
    28921 ctgaatttcc ttcattagaa aacttactcc accttaaatg ttgatgttca tcatcaaata
    28981 tcttttcaaa agaaacaccc aaaagagttg cttctgcttc attttttgtt tctacttcat
    29041 ccaatccttt aataaataaa agatatgtaa attgttctat aacttctaat ggattagtta
    29101 atccaccagt ccaaaaagtc tcccaaatct tgtccacttt actccttaat tctcctgtaa
    29161 tcatatatga ctttccctcc agtgttcata aaataattta aatatatatt ttagtcgtac
    29221 gccttaatag ttagtgtctt atgttaaatc caagttttta ctacacaatt attaaattat
    29281 ttttcctatt tacatatttt agctaaaaaa ctaatgcaat actcttattt tatgattatt
    29341 atatatacca tacaaaatta ttttatcata tatccatcat agaagtcatc tacctggata
    29401 actcttacca tattataact ttttaatatt aatttaaact tagaaagaaa ttttttattt
    29461 aattatatca tcttccttat ttcaaatttc tcaattacaa tcttaatcaa aaaataaaat
    29521 aagatgctgt ctcaaaatag atataatctt cttttttatt gtcggaatga tgaaaatata
    29581 tttaatttca tacaaaaaag agtgcctcat gaactaaaag ttcattttga gacacccctt
    29641 aatttaatct tacttattct ttccctttat tattaacact tcactatctc tattgctttt
    29701 cctacacatc cacaaacttc catcctactc ttaacaaaat ctttaactga ctctaaacct
    29761 tttttaccat attttttagg gtcaattacc tctgggtcag aattaagcac atccttaacc
    29821 ccattgctat aagcaatcct taattcagtt gcataattaa ccttgcaaat ccctcttttt
    29881 atagactcct taataacctc atctggtatt ccagacccac catgtaatac taatggaact
    29941 gatacaacct ctctaatttc agataatcta tctaaatcaa gttttggctc tcccttatat
    30001 agcccatgtg ccgtacctat tgctactgct aaagatgata cccctgttct ctctacaaac
    30061 tcttttgctt ctaatgggtc tgtatatgct ccaccatcac caccatctaa atcgtcttcc
    30121 ttacctccaa ctttacctaa ttcagcttca acaggtatat ctgaaggcat acatgcatct
    30181 acaacagatt tagatattga aatattatct tcataacttt catgagaacc atcaatcata
    30241 atagaagtat atccaactct aagtgcctgc atagctagtc caaagcttga accatggtct
    30301 aagtgcattg ctactggaac acttgccttc tctgatgcta cctttacatt cgctaaataa
    30361 taatctagtc ctgcatactt tattgttgaa ggtgttgttt gcaatattac tggtgattta
    30421 agttcttcag cagcctctat tactgccata accatctcca tattttcaac attaaatgca
    30481 cctactgcat aatgcccttc ttgtgcatct aataatattt gtttagttgt cactaatgcc
    30541 ataatttctc ctcctatatg tttatactga tttaatttct tcgttattta attttgatac
    30601 tatttctcta cttgttttgc tatttaataa ctcatttaaa aattcttcat tcattaattt
    30661 tgaagatagt tgagataatg tttttaagtg taaattatca ccattatctg tagctgctat
    30721 cataaatata atatgtgcca agcttccatc ttctgattca aagtcaaacc cttcttttga
    30781 tagacctact gctacacgtg gtacctttac tgcatctgtt tttgcatgtg gtatcgctat
    30841 ccccatacca aaacctgtag atgatatttc ttctctttta aggatttctt ctttaaactt
    30901 ctttttatct aaaagaacac tagatttatc aagtattcca atcatttcat caattacatc
    30961 tgttttattt tttcccttaa catctaaaat tactgtttct tcgctatata aagagatatt
    31021 attagatacg ttttccgatt ctgcactttc atttttatgt tcatcttttg ttacatttgt
    31081 attttctata gtatttttct catttactac tttaggtgta accatcatat aaagtacagc
    31141 acctactaat gaacctacaa atatacaccc tacccataaa agtggcttat tgactaatcc
    31201 tagaaccaaa aaccctccat gtggagctgg tacttctatt ttcattatat aagttaaaat
    31261 tgatgatatt gatgatgcaa tcataagtac tggcaacact tttaatggat tttttgctgc
    31321 aaaaggtatt gccccctctg ttatatgagt actacctagt atataattga ttaatcctgc
    31381 tgctctatct tcttctgtaa atctattttt aaataaagta gatgctattg ctattaccaa
    31441 tggtggtgtt atacaagctg cagatacacc tgccataaat aaataatttc cctgtcctag
    31501 aagcatagtt ccagttacat atgctgcttt atttactgga cctcccatat caaatgctga
    31561 catacatcct attactattc ccaaaattat agggcttgaa ttttgtaacc ccgatagaaa
    31621 gttcatcata gcattgttaa gtgctgaaca tggcccacca agtaacaaca ttgctacacc
    31681 cacaagacct acgctgacaa taggaattat aaaaatcgat ttaagacctt ctaattgtcg
    31741 tggtaatttt cttaacaaat gtacaaatag tttaactaag taacctgcta aaaatcctga
    31801 tatgattcca cctaaaaacc ccgaacctgt atcaaatgat atcattcctc caacaagtcc
    31861 tgccaacata ccagctcttc ccgatataga ttgagctata aatgctgcca atacaggaac
    31921 catcaagttc atagaatatc caccaacaga ttttaatgta gctgctattt gattatattg
    31981 ttctgaattt gggtcaaatg aataaatccc ccataaaaat gatatagcag taagtactcc
    32041 acctgctact actaaaggta acatgtgaga tacaccattc attaagtctt tatacaactt
    32101 ttgaccaaac gataaatttc cttcttctgc aattttactg cttgataagt ttccttttct
    32161 aatagctact tttccatcaa tacatctttg tataagttca ttagctttat gtataccttc
    32221 tttgacaggt acttctatta ctggctttcc attgaatctg tccatatcaa catttttatc
    32281 acaagcaact attattgcat ctgccatttc gatatctttt gctgttaact tattttctac
    32341 acctatagct ccattcgttt caacttttat gtcacaccct aattccctgg ctgaattttt
    32401 taatgcttct tctgccataa aagtatgagc tattccagtt ggacaacctg ttacccctag
    32461 aatcattttc tttcccattt ttataccacc tttctgactc ttatattttt tatataatct
    32521 tccacattct ccaaattacc tataccatta ctttcagcca cacttgctcc tgttgctgct
    32581 gaccttttta atgcttcttc aatatgttct ggattttcca accatatact taaaaaagca
    32641 gctaatgcag aatcaccagc acatgcagag ctgactactg taactggttg agcactagca
    32701 taataaattg attttccatt ataaaaataa gaaccttttt ctcctaaagt tagcaatata
    32761 ttttgagcac cttttaaatg tagtaattta agtacatcct taatatcttc ttcatctctt
    32821 acaataattc caaatatatc tttgatttct tcatcatttg gttttatcaa atatggatta
    32881 tactgtagta actcctttaa ttttggtgaa cttatatcga gtattgtctt tatactttta
    32941 ttttcacaaa ttttaaatat atcctcatag taattatcat caataccagg aggtagactt
    33001 ccacttattg ataagtaact tatatcttct aatgactgta tcttatctag catatctagt
    33061 ttttgttttt cgtttacata tgacccagag tttacaaatt taaattcatc acttccatca
    33121 tttaaaaata tatttatacg agttgtatct tctacccaag taggcaatac gtcaaatcct
    33181 ctcttttcgc tttcttcaac tatatatttt cctgaaaatc ctccaaaaaa tcctaatatc
    33241 ttagattcta taccataatg acctagtaca aaagttacat ttaatccctt tccattagga
    33301 gaatatacag catttgatgt acgatttact aattttctct ttatcccatt agtagatata
    33361 ttcatatcta ttgcaggatt tgtagttaat gtatatatca ttgtcttccc ccttgcttgt
    33421 gctgtgtatg ttttcattat aataaaaaag tctatgaaaa tcttttcaca aatagaaaat
    33481 cgattttcat agacttttca atttaatttt cagaattatt atatctgacc atataatcta
    33541 taattatcct agatataata tacaagggca atctggaaga tacttcatat tcagaaattg
    33601 atatatgttc atgtttgtat cctacaatat ataaatccga atactttata agttttgcac
    33661 tttcactaca acagcaagtt ataaccttag ctccaactaa attggcattc tgtgctgatt
    33721 ctacaagctc tattgtattt ccattcaatg aaaatataat tataagttcg tcttttttta
    33781 ttgatttaga ttttattttc attatgttgg ggtcatttat aaaaacaaca ttaaaatcaa
    33841 gtaattgcaa tttaagacta aactcttttg ctacatattc agtaagccct cttgctaaaa
    33901 tatatatctt actagattta tttacagttt ttattatatt gattagtgta gttaaagata
    33961 tttgttctat aactctctgt gcttctataa aggatttatt tattatatcc cccatatttt
    34021 gtatatcatc attttcatct tttactgtta atctatacct aagttcattg aatccattta
    34081 aaccacattt tctaattgct cttgaaacgg ttgctggaga tgaatatgtt tcatgagcaa
    34141 tctctactat agataattct ggtaatattg attcattttc atttataaat ttaattattt
    34201 caagttccgt cttggttaga ttttcagaat tacttttgtt tagctcaatt atcatatgtt
    34261 atctcccctt atataagttt tatttgtcta aatttatcga gtaatataat atattacctc
    34321 ttaactactt atttttatat acaattaaga tttagtcaat gtctatatat gtaaatttat
    34381 aatataataa ttttttgctt aaagtttatt atgttatctt atagcatttt aaaataaaaa
    34441 agaattgtac ctctaccaaa atttggatga agtgcaatag atattcctta tactgatatg
    34501 tttatgatta aaagtataaa tataaatttc gctatgaatc atataattaa taaatcattt
    34561 tatttacaat tataaccccc cttataaaac tatattaata atatatacag tatttataag
    34621 gggggttgtt tatatttaaa aactatttac ttttctttta attcttctcc attagttctt
    34681 attacatttt gataccaata aaaactatct tttttataac gttttttact tccatttcca
    34741 ttgttatcta tatctacata tataaatcca tatctttttt ccatttcttg agatgaacaa
    34801 cttactatat ctattggtga ccacatacaa taagctaata tttcggttcc atcagctata
    34861 gcttcaccta tttgttctat atgttttcct aaataatcta ttctgtaact atcatgaact
    34921 tttccatctt caaatttatc atgcattcca aatccatttt cagctatcat tattggcttt
    34981 tggtatctat cataatattg agataaagta ttgtataatc cttttgggtc aattgcccac
    35041 ccccaaggat ttgcttttaa atatggattc tttatattgt cagttggatt catggtgttt
    35101 ttacttgctg atactgttgt agaataatag tatgataaag ctagaaaatc catagtattt
    35161 tcttttaaga ttttatcatc accttcctcc ataactatat ttatgttatt ttctttgaaa
    35221 aatctcttaa tatagactgg atactctccc ctaaaactta catcagtgaa aaaatattgt
    35281 agcctatttc tttttaaagc aaatactaca ttttcagggt cacaatcttc tggataagat
    35341 gtacaatctg ccatcatcat acctatcatc atatctgaat ttatttcttt tccaagcttc
    35401 ttagtcaaag ctgtagctat gaattgatga tgaatagctt gatatctagt ctcttctaca
    35461 ttatctactt ggtctacaca aaatgcaact gaattaaatg attcataatg tattaaattt
    35521 atttgattta taactatcca atatttaact ttatttttat atctatttag tattaattct
    35581 gcatatctaa caaagaaatc taccactttt ctattagacc atcctttata ttttaatact
    35641 aaattcaaag gagtctcata gtgaagtagt gttacaatag gttccatacc attatctatt
    35701 acttcattta taagattatc ataaaacttt aatccctctt cattaggctc taaatcatct
    35761 ccatttggaa atattctagc ccaatttatt gaaaatctaa aacactttaa ccctagctct
    35821 ttcaaaagct ttaaatcttc tttgtatgta tgataaaagt ctattccact acgcttagga
    35881 taatatccat tattatcttt catagcaaac tttattcttt ctatagtcat atcagactca
    35941 taaggtttag atatatctct atctttatca tacatatgta catcagctaa acaccaacct
    36001 ttgccacctt cattccatgc accttctaat tgattagctg ctacagctcc tccccataaa
    36061 aaacctttag gaaacttacc caatttaatc actccttatt ttatttattt aaatcattta
    36121 ctattattta ccttatattc tatagacttt actattccta ctaaagacat agttatattt
    36181 aactcgctga atatggtcat aagagtatct tgagcatgtg caaataacag cgaatgtgct
    36241 cttttctctc caccagcttc cccttgtata atcttggttt gagctctatg tgcttctgtc
    36301 ataaaccctt ttgctttagc tagttttaaa tcagcatttc tataatcaaa cttttccaaa
    36361 tcattaagag catgtttaat ttctgttcta gcctcacctg cacgaagtat tatttgcatt
    36421 gccacctcta ctaattcttc atctattata tgttcttcaa ttgtcatatt tataatttcc
    36481 tttcaatttc taaatttaaa cctcttggct ctctaatttt atctcttctt tctcataagc
    36541 tttaaaaaat ggataccata tcataaatag caatactata tttattgcta aaacaataag
    36601 acctctaaca tcttgattta ccgtaaaagt agatatacca aaaggaacat accataaatt
    36661 aaacacctta cttggaattg tcacaaatcc catactcatt gataagtaag tagttattga
    36721 tattactact gttcctatcc acataggtaa cattaaaaat gggttccatg ccactggagc
    36781 tccaaatatt actggttcat ttatattcat tatagaaggg acaatacatg ctcttcctat
    36841 tgcttttatt cttccaactc tggataaaca catcattata actaatggta atgtagcacc
    36901 caaccctcct aaagttatcc aacctgtttg aataacttcg taaacatata tattagttgc
    36961 tactcctcct gatgctactg ctgctgcatt agctgcaatt gcaccaagtt gaattgaata
    37021 agttatagga gatagtaccc acccacttat tcctaaagaa tatataaata ctactaaaaa
    37081 gtttaagagt acaaatccag gtaatgtctg tgctatatct gatactggtt taaatactct
    37141 aactattatt tcaaacatgt caaagttgag tccataaatt aatccccagc ctacaaacat
    37201 tatcactgtt ataggtaaca tattatcaaa ccacttgctt acaaaatccg gaagtgctga
    37261 atcttctccg aaaaatgaaa aagaaccaaa taaggacatt attaatccag agaataatcc
    37321 tgcaactagc gatacaagca ttccttctcc tccaaacctg ttgaagttaa atatagctcc
    37381 ttcattcgta atctctggac gaatcatcat taacattaat ccagcacctg caagaccagc
    37441 gactacactc atactttcaa atttcttatt cttcattatt tccataggca ataaaaatgc
    37501 tataaataat cctaaaagtc caaatgtata ttgatttatt ggacttaaat caggtaaaaa
    37561 gcttatgtaa ttcttcaaga cagaaactat agttactaat gagcctacaa ataccattgg
    37621 caaaactttc attatagttg attgaactga ttgtacccat atattcttag tcatattatt
    37681 tacaacagga gtaaattttt cacttaaaaa atctataaat ttattcataa acactctccc
    37741 cataaatatt ttatttgttt gatattagtt ctagtgcttc ttccaaagcc tttgccccat
    37801 ctagtcttcc atatgcagtt ttagatatac atgctactgg aacgttatat tcattagcct
    37861 tttgttgaat ttcttccttc atataatcta aatgtggtcc tagtaataaa caatctattt
    37921 ctgataaata cttatctatc tctgactcac ttctcgcttt tatatctgct tctatacctt
    37981 ttttctttgc actctttctc atactagttg ccataaaacc tgtacttgct cctgaaccac
    38041 acgccaaaag cactcttata tttttcataa tgatacctcc aatattttta tccatcaatt
    38101 tatttcttaa tgaacttttt attttattat gtttatattg tacttaccaa ataagttcat
    38161 ttcacataaa tatatttcct aataatagga aatcagttac tcttaattaa acatattaat
    38221 atagtataat gtatcttata atacgtacat tcaattatat aattatcata tcatccagat
    38281 tttattttaa aactatgcga gggaatctaa tgaaaacatc taaaaaagaa ctatttttaa
    38341 atttcataaa aacacaacat gattggatag attcatctac attggctaat tatcttaatg
    38401 tctcaacgcg ttcaattaga aaatatgtaa acgaaattaa ttccaatggt gaatttatat
    38461 tatcctctaa aaaaggatat aaagtaaatc tcaataataa ttgtcaaacc aaggttgata
    38521 gttcagaaaa tatatcacct gataacaggt taaatttaat tttaaaagaa cttatagtta
    38581 atagtaatgg aattaatata tttgatttaa gtgaagactt gtttgttagt ccagctacta
    38641 ttgaaggaga tatagtcaaa gctaataaat ttataggaag ttataattta aagataaagc
    38701 aatcgaaatt tttattgaaa ctaattggaa atgagtctgc aaagcgcaaa ttaatgagct
    38761 ctataatatt taaagaaacg ggaagtgatt ttttaagctt atttgatgta caaaaaatat
    38821 atcaagagta taatttgacc aaactgaaag aaaatataat atatatatta aaaaaataca
    38881 atttgt
//
LOCUS       DAEPKC010000027        38587 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.027, whole genome shotgun sequence.
ACCESSION   DAEPKC010000027 DAEPKC010000000
VERSION     DAEPKC010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 38587)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38587)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38587
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.027"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..1305
                     /locus_tag="KR294_001472"
     CDS             <1..1305
                     /locus_tag="KR294_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH0239554.1"
                     /translation="LHLMITIDRIKKNNYIESVEVVNYIDNNNDISISRDISNFLESE
                     YNITLTSAELYYLVFQLTNKTTVLNYHEMDTKSLPNYIDEHFVKLTKKIIKNVYDLYF
                     IDLSDDEFVVKFTLHVKNLISRAKNNQVLRNQIPQKLKDSYPLIYDISVYICNQIQIL
                     ENIEIDEDEISYISLHVGSFFDRQKLLEDKILCALITPNYYDLQFKIVRDLEKRFNES
                     IEIIQIFSDTHNLDFDNKVDMVITTLPISDRCPIPFVYVNPYLNRKDYDNIQSKFIQI
                     KDRKNILTVQNHLEMYFSESLFMKNIYLDSAKDYIRFMGNILYENKYVKPNYIDDVLI
                     REKMSSTAFNNNVAIPHSMKMDALKTGVCLIVNDKPVKWGEEKVQIIAMIPINEKEKE
                     KFNYIFESFIEILSEWNNVKELTKADNYSSFMNRIAYLIQNI"
     gene            complement(1428..2582)
                     /locus_tag="KR294_001473"
     CDS             complement(1428..2582)
                     /locus_tag="KR294_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HBH0239555.1"
                     /translation="MKILISIDSLKGSLSSIEAGNAIKKGILKVKEDAQVKILPLADG
                     GEGTVDALVQGMNGKKDTIEVTGPIAKKVDATYGLLKNTSTAIIEIAQASGLTLVPTE
                     LRNPLYTTTYGVGEIIKEAINKGYRNFIVGIGGSATNDAGIGMLQALGFEFYDENNKL
                     VGLGGKVLNEIRHIKIENRLKELDECKFKIACDVNNPLFGKNGAAYIYGSQKGATSEI
                     IEELDNGLRNFSKVVKNYLSKDVANVEGAGAAGGLGFAFLAFLNSKLESGIKIILEEI
                     KLEEELKDADFVITGEGRLDNQTAMGKAPIGVAKLAKKYGVKVIGLAGATTEDAVKCN
                     EEGIDAYFSIVNRAMTIEEAMDKATASENMTATTTQIFNLITSIQQSKNM"
     gene            complement(2842..5457)
                     /gene="mngB"
                     /locus_tag="KR294_001474"
     CDS             complement(2842..5457)
                     /gene="mngB"
                     /locus_tag="KR294_001474"
                     /EC_number="3.2.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosylglycerate hydrolase"
                     /protein_id="HBH0239556.1"
                     /translation="MKKNVHIVPHMHWDREWYFSTEESRILLVNNMEEIMDMLENNHN
                     YPYYVMDGQTAILEDYLAVKPECKERIKKLVQEGRLIIGPWYTQTDEMVVGGESILRN
                     LLYGIKDCDEFGEYMKIGYLPDSFGQSAQMPQILNGFDIKYSMFWRGCSERKGTNKTE
                     FNWKSDDGSSVLVQILPLGYAIGKYLPMNEDELRTRMDKYLPVLDKGATTDHIILPNG
                     HDQMPIQKNIFEVIYKLKECYPERKFFLSRYENIFKELEKNEDIDTIKGEFLDGKYMR
                     VHRSIFSTRMDIKSANARIESKITNILEPLASIAYSLGFEYHHGLIELIWKEIMKNHA
                     HDSIGCCCSDKVHHEIMNRFFLAEEKVDQLITFYKRRIVDAMSCEMALDKLVAFNLMP
                     YDRNEIVSAQVITKMKAFEIFDKDNNKLDFEVVHKEVIDAGLIDRQIVHYGNYDSFMV
                     YTINFKDKIPAMGYKAYMIKEVEHMLEKAYEVCDMVDNDFYTIQVNENGTLKIFDKKL
                     NKTFENVLLMENGGDEGDEYDFSPLPNEKLIFNDNIVANSTIKKNRFNNEIKINYRLK
                     VPKDIQARKNNRADSFIDFDIVINVPNDKAIIDVVFNINNQARDCRVRTYIPTNIASK
                     FSVSDNQFGHIKRSVYDDAMEVWQQEEWSERPDSIYPMLTFVGLSDKEHGVAVLTNST
                     REFEIVGEKFDTIAITLFRSVGFLGKEEMARRPGRPSGIKLPTPDSQMIGDIKIDLAI
                     VTHEKSTLEANVANMAKEYLTKIQTYNKMPYNAMKLNQSEIEVDYSYSLLKETNKDLV
                     LSVVKKAEKQEALVVRFYNSKEETKSANIVFNKNIKTAKWINLNEKELESISIDNNSV
                     NVECLMNQVKTILVK"
     gene            complement(5601..7526)
                     /gene="mngA"
                     /locus_tag="KR294_001475"
     CDS             complement(5601..7526)
                     /gene="mngA"
                     /locus_tag="KR294_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS 2-O-a-mannosyl-D-glycerate transporter
                     subunit IIABC"
                     /protein_id="HBH0239557.1"
                     /translation="MEFKKITNENLVFLKQKIKTKKDAIKFLARKLYDEGKLTSYEEY
                     LEAVMYRETLSPTGFERGLAIPHGKSKSVKEAAFAAMTLETPIENWESVDPNNKVEII
                     FLIAVPENEGGNTHIQILSELVTRLSNEDYMNMLLNSKTKKELFNNLDIKEKKEQIKE
                     EIRIQNESKKIILAITACPAGIAHTYMSAEALIKAGKEIGVDVYVEKQGANGMVDPHT
                     PDIIKRADAIIYATDVAPKNTERFEHLPNIKTSVAAPLKRAKEIIYEALEVAQKQGKG
                     DYIEKSSDISYCEKSSWKKDVKSAILTGVSHIIPLIVAGGMILAFAVLASQAFGLQEL
                     YNQEGSWLWQLRKLSGGMLGTLMVPVLSAYMSYSLAEKPGLGPGFAAGLAADLIGSGF
                     LGGMLGGLLAGYIVKFLKKNIPAKGTLAGFVSFWVYPVVGSLVVGLLMLFVVGKPVAA
                     LNNGLINWLNGMTGVNAILLGAIIGAMVSFDLGGPINKAAYTFAIGAIASGNFIPYAI
                     FASVKMVSAFGVTIATVLGRDLFSESEKEIGKQTWILGLAGITEGAIPFMIEDPIRVI
                     PSLVAGSAITGSIVAFFNIGLQVPGAGIFSLALLEGSMSGFIIASIWFFAAVLGAIIS
                     AVLLIITRKQKNQRKIH"
     gene            complement(7656..8381)
                     /locus_tag="KR294_001476"
     CDS             complement(7656..8381)
                     /locus_tag="KR294_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBH0239558.1"
                     /translation="MEFYERAKKYEYKFTDTEDMIIEYMRKNKEEIVKLSIQSLADKF
                     FTVPNTIVRLCKKMEYDGFSQLKNNLKEELKNEDKEPKNGFESDIKKTLELIDYEKIN
                     KVADIIQKSRSIIVYGIGQNIPLCEILVKEIRGGHDNITYYSQRHEVLHDIGKLGEQD
                     MFFALSLSGETKEVIEVAKTAVNKGCKVVALTHICENQLQQIADISLYCYSTIKQVNG
                     YNISDKVPIMMIMRAIIEQYWLR"
     gene            complement(8644..9414)
                     /locus_tag="KR294_001477"
     CDS             complement(8644..9414)
                     /locus_tag="KR294_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ChbG/HpnK family deacetylase"
                     /protein_id="HBH0239559.1"
                     /translation="MKKLVVRADDIGYSEGVTLGIISSYKNGIVTSAGIMVNMPFSRQ
                     AIEMVKNDDVCFGLHVNLVIGEPCCKEHIKIKNLLDEGGKFVSSKIRRTQLLTGKEVF
                     NYEEVYEEVCAQIETYKLYMSKLPEYIDIHGIEEDVSISAMCDAAKEYGIPSCPYYLD
                     SCISMPSKYPQNDFYKLNKSFVKLFEEKYINLDKDITLMVTHPGFIDYSLIKSSSLIQ
                     ERVYEHAMLCDKEVKMWLKRNNIELVDFKDIFKSNNYI"
     gene            complement(9416..10843)
                     /locus_tag="KR294_001478"
     CDS             complement(9416..10843)
                     /locus_tag="KR294_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBH0239560.1"
                     /translation="MMQQLSLLGKTMLVPIAVMPAAGILGLLFGPNMLNVPAISNISN
                     IVFSNVDYLFLLGAASAYSKSKDKTSVMVAAVVAYMIFKSNLELLNDTLNAGVFGGII
                     VGACIAWTYNKTYKVKVPAFLSFFAGEKCVITLSPVVALILSYIFSLLWIYPQAAMNQ
                     FGFWLGGAGAIGIFLFLFCNRALIPTGLHQVLNAYILFEMGEYTTSTGEVIRGEIPRF
                     MAGDPNAGFFWTGFYIIMMFSIPAISYAIYKTAQDKKKQEVKGAMTAGALTSFMATVT
                     EPIEFSFLFASPKLYIIHSFYSGLGGVVLYLLGVRLGSFNGASIIDYVLSFSYGDKAW
                     LVIPVGVVFFVLYYVTFKYIIIKDNVQTPGREVEIEIGDKVSEKEKNLKLSHGNFSYM
                     AKQIIKNCGGYENIVTLNNCMTRLRLEVKDATILNDDNIKKTGAKGVIKLSNTSVQII
                     IGTDVVKVKDEMEMQLDELRKQADA"
     gene            11234..11956
                     /locus_tag="KR294_001479"
     CDS             11234..11956
                     /locus_tag="KR294_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH0239561.1"
                     /translation="MAKNKFSEIYEVLKEEILDGKYTSNMMLPTELQLIERFSCSRNT
                     VRRAISQLNTEGYVQSIKGKGVVVLENSCSNDFFLNMHNFKGVESIVEDKKVNTATSV
                     LHFSKILIDNKLSKKTGFKVGSEVYYLHRLRYIDNIPKILDINYFLCSIVKDLDVSIA
                     QGSIYKYIEECLGTKIVSSRKIFKIEKATELELKTLPLNDYNCVGVIKNSVYTDDGKL
                     FEYTESKHTPETFVFMDVTQRY"
     gene            12153..13820
                     /locus_tag="KR294_001480"
     CDS             12153..13820
                     /locus_tag="KR294_001480"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HBH0239562.1"
                     /translation="MKNWWKKATVYQIYPKSFKDSNNDGIGDINGIIEKLDYLYYLGV
                     DLLWLTPMYVSPQRDNGYDIEDYYNIDPKYGTMSDFEKLLKEAHKRDIKIMMDMVLNH
                     TSTEHKWFKESKKSKDNPYRDYYFWKDAKPDGSVPNNWISRFSGTAWKYDETTNQYYL
                     HLFEETQADLNWENEKVREECYKILEFWADKGIDGFRLDVVNLLSKTPGLPDDPITGP
                     KGDGRTHYADGPRIHEYLHNMNQKVFKPKNIVTVGEMSSTTPEECINYTRENREELSM
                     VFSFHHMKTDYKGGAKWTNEMFSLDKLKKAQSDFQYKMYEGKGWNALFYSNHDQPRAL
                     SRFGDDRFFRQESAKMLAITLFGLQGTTYIYQGEEIGMTNAYFTKIDEYDDAESKNAY
                     YHMIKSGIDEKEALLILQQKSRDNARTPMQWDNTIYKGFSNHKPWLKVNNDNISVENE
                     LNDSRSVFYTYQRLIKYRKQYDIFTEGTYRLLDENHKNLFVYEREYKNQNLLVISNFT
                     HDNVVYKLPETYLNKLNYTILETNYTRDIIENKMEIKPYESIMIYYK"
     gene            complement(13916..15235)
                     /locus_tag="KR294_001481"
     CDS             complement(13916..15235)
                     /locus_tag="KR294_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBH0239563.1"
                     /translation="MEKGIKLGFWSIVLLGINAIIGSGIFGLPGDAYTDIGPASILVL
                     VFCMLLAVSIALCFAEAGSWFDTDGGPYLYAKEAFGDFVGFEVGFMKWIVSMIAWATM
                     ANFFAVTLSSVWPQAAEPLIKNIIIGILVVGLGIINFMGMKQSKHLNNIMTIGKLLPI
                     VLFIAVGLFFIKGSNFTPFVIIQKGQSASSAFVAVSITLFYAFTGFESLAVAAKDMEN
                     PKKNVPKALVMVMFVVSVIYMLILGISIGVLGNGLAGSATPVADAAIKMLGPIGGYII
                     TIGTIVSVGGINIASSIFTPRSAAALVEQGLMPKSIRQTNKNGAPYIAIIVSVIGTLL
                     IAWSGSFTTLSQISVVSRFIQYIPTCLAVLILRKKYAGKDVNFRIPGGAIIPIFAVII
                     SILLLIKAGIDEPMKIVWGLGGMIIVVPIYFYMTKVYSKKYNDVEVK"
     gene            complement(15276..16022)
                     /locus_tag="KR294_001482"
     CDS             complement(15276..16022)
                     /locus_tag="KR294_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HBH0239564.1"
                     /translation="MKKLAKKKYPIIGISGNLLIDEGGMFPGYERAYVNNDYIQSVVM
                     CKAIPYIVPIVYDDEIIKEQVSNIDALILSGGQDVNPLIWKEEPHNKLGAISPKRDSF
                     DMKLLKHALDMKKPVLGICRGEQIINVTEGGSLYQDLSLIEGAYIKHNQQHLSNVPTH
                     TVQIKEGTKLYEILGEKEVLVNSFHHLVVNKVAPGYIVSATSKDGLIEAIEKEGSEFV
                     IGIQWHPEMMTRDYDNMKKIFMAIVKEASK"
     gene            complement(16266..18275)
                     /locus_tag="KR294_001483"
     CDS             complement(16266..18275)
                     /locus_tag="KR294_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH0239565.1"
                     /translation="MKTIAVVTDGLSKLECFLNKNLEMIFKDKVMIKNYYLNKITEKE
                     LIKDDIILVMIDDRVLKIKKYVEDVSKIITINRSIKQKDIYKLFSLPEGIDVLVVNDN
                     KHTVLETISNLYNIGINHLNFIPYNPNEEYRNIKIAITPGESSLVPKYIEEVIDLGHR
                     YIDSSTFIQIIAKLKLDDKEITERLIKYTDEIISLYSGINTKYKELTIKADELNSIIN
                     LSNLGMAMVSDKGNIIICNNSLRDILDIQSNIIGKNIDELENENIKKIFSLSKAHDEV
                     IKFNNKYLNVNKYNIESFGRVTGYYFCIQEITYIRKLEQNLSKKLREKGQVARYTFDD
                     IKTVSTKMERTKKLGMKIAESDYTILITGESGTGKELMAQSIHNASPRHSQPFIAINC
                     AAMPENLLESELFGYEEGAFTGALKGGKKGLFEQANNGTIFLDEIGDMPIYLQSKLLR
                     VLQENQVMRVGGENVIDIDVRVIAATNKNLLEMIKGDRFRADLYYRINVLPINIPPLR
                     ERKEDIEVMLKHFMKRKRAISQDVQDIINAYEWPGNIRELKNTAMYINIMSSEDVILI
                     NDLPHNLLNITEDFSKEISILKDRTSIEKVKLVMECLKNANNLNKNIGRNGIVNSINE
                     LGYNITEGEVRGILNMLKELDLIICESGRKGSELNRRGKNILNSI"
     gene            complement(18669..20102)
                     /locus_tag="KR294_001484"
     CDS             complement(18669..20102)
                     /locus_tag="KR294_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBH0239566.1"
                     /translation="MALRKDFLWGGATAANQCEGAWNLDGKGPSCSDMCTGGSQKVSK
                     RITRVIEKGTFYPSHEAIDFYHRYKEDIALFAEMGFKVFRFSIAWTRIFPTGMEKEPN
                     EAGLKFYENVIDECLKYNIEPLITISHYEIPFAITEKYNGWVSRDVIDLYMNYCETIF
                     KRYKGKVKYWLTFNEINSATMPMGGYLSQGILNEGTTDFINQVDIPQLRFQGLHHQFV
                     ASAKAVKLAHEIDSNYQVGCMQIFATMYPYTCNPDDAVKTQRDSRVMNYFCGDVQVRG
                     EYPTYMNRYFGENNIEIKMEKGDLEILKEGCVDFYTFSYYMSTCVSSDSKEDNTSGNI
                     LGGVKNPYLKSSEWGWQIDPEGLRYALNEIYDRYRIPMMVVENGLGAYDKKESNGVIN
                     DDYRIEYLKAHIEQMKEAVEDGVDLFGYTPWGCIDLVSASTGEMAKRYGFIYVDKYDD
                     GSGDLSRIKKKSFDWYKQVIESNGERL"
     gene            complement(20189..22105)
                     /locus_tag="KR294_001485"
     CDS             complement(20189..22105)
                     /locus_tag="KR294_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBH0239567.1"
                     /translation="MRKYEQLSKEIIANVGGKDNISSLSHCITRLRFKLKDESIANDD
                     VLKKMDGIVTVMKSAGQYQVVIGNHVPDVYEVVCDLAGLGGDTIDNSDSDAPKGLLNK
                     FIDIISGVFQPILGVLCAAGMIKGFNAVFTALGLYGETDGAYIMLNAIGDAMFQYMPI
                     ILGYTAAKKFKLKPFIGMLIGAVLCYSGIQLDTLASTGQPLYNLFTGTIFESPVYITF
                     LGLPVIAMNYTSTVVPVILIVLLAAKLEKVFAKIIPDVVKNFFVPMAVLLVSLPLGFM
                     VIGPIATYASNIVGNGFLALFNFSPILCGALTGLLWQVLVIFGLHWGLVPIAMSNLMT
                     MGFDTILVGVFVPSFAQTAVVAAMYFKLKDKKIKELCIPAVISGICGVTEPAIYGITL
                     PRKTPFIYSCVGGAVAGAVMGIMNVKSYVMGGLGIFGIPNYINPTTGDMKGVYATIIA
                     IIVAIVVGFVLTLFFWKDDAIVEISKDDNGQGVIEKNKREVVYSPIKGEVKALEQIQD
                     AAFSTGILGKGVAITPKEGKVVAPFDGTVMTLFPTKHAIGIISDNGCELLIHIGLNTI
                     QLEGKYFKSFVNQGDKIKKGQTLITFDIESISKEGYCLETPVVVTNYSDYVDIVENTQ
                     KHVNNSQKLITVLA"
     gene            complement(22179..23039)
                     /locus_tag="KR294_001486"
     CDS             complement(22179..23039)
                     /locus_tag="KR294_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBH0239568.1"
                     /translation="MIIEKILNNNVIITTDENHKEIVVMGRGLAYKKRTGEHISKDKI
                     DKIFKLSDPNISDKFKELIADIPIRYMELSDEIILYAKEKLGKRLNDSIYISLTDHMY
                     TAIERAREGVSVKNVLLWDIKRFYKSEFKIGLEALDYIEKKFEIRLSEDEAGFIALHI
                     VNAQMDQSIKTIYEITQIIQEISNMVKYHYRIVFDEDSVYYHRFITHLKYFAERIVSN
                     NLHENNEDDLLNVIKVKYKNAYKFIEKLDEFIHKKYNYDLTDEEKLYLTIHVERVVSK
                     SIKSDINPNN"
     gene            complement(23390..24577)
                     /locus_tag="KR294_001487"
     CDS             complement(23390..24577)
                     /locus_tag="KR294_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBH0239569.1"
                     /translation="MIESIKKRAYEIENELGKEIEEVCNFIFNNPELGEEEYISSKYL
                     VEKMKEYGFDTVYPYCNMETAFRAELGDNDGPTIAFLAEYDALPGYGENKEPAHACGH
                     NWIAASTLGACIVLSKLKENFKGKIVLIGTPAEETTGGKCDLVKAGAFDDVDVSYQMH
                     IEAFNNINCKALAIDSLEFSFEGVSAHAASHPHMGVNALDAVQLTFAGINALRQHVKS
                     DVRIHGIVSNGGEAPNIVPEKAACKFFVRAAERSYLDEVTKKVINCAKGAELMTGAKL
                     SYRYFENSFDNIINNKVLQKITKNNLIEAGITDILEGKDGPVGSTDIGNVSQVCPTMY
                     TEIALDISPMVYVHEKEFLNYANSEEAYDKLHKAVKAMVGCALEIYLEDGLLDEIKKN
                     HLN"
     gene            complement(24591..25982)
                     /locus_tag="KR294_001488"
     CDS             complement(24591..25982)
                     /locus_tag="KR294_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HBH0239570.1"
                     /translation="MSSLKKKKFTMPQTLTIIFLLIVLMAILTWIVPSGNFERVDIDG
                     RSVVVAGTYEKAPSNPQGITDVFTAPINGFIDAAEVVGFVLIVGGAFGIVNKTGAIEA
                     VIAHTVNKMKKFQFLIIPISMILFGLGGTTFGMSEETLPFYMIFIPLMTSMGYDSLTA
                     VATVFIGATAGFGAATTNPFSVGIAQALSQIAPGSGIEFRVVMFIIYMAISIGFVMMY
                     ANKVKKDPKKSLVHDISLNQESMVNSDTNIKEFTKREAMVIAIFTIGMAIMIYGVLKL
                     GWYITEIAMIFTAIGIISGIASGLKQDDIVNSFISGAGDLMTAGLCIAFARGIVIIAE
                     NGFIIDTILNSAANLLNGLPKTIFINLTFLIEGLIAFLIPSASGLASLTIPVLAPLGD
                     LVDVSRQMIVTAYQFGIGVTNLITPTSGVLMGALAVANIPWSKWVRFVIPLMVVLTIL
                     VMAFLTIGLYLGF"
     gene            complement(26577..28277)
                     /locus_tag="KR294_001489"
     CDS             complement(26577..28277)
                     /locus_tag="KR294_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBH0239571.1"
                     /translation="MHYIAWHFNKNGGNNTMKDKLQVLSGAMMIPVILLVVAGVFIGL
                     GSAFANMENVSALGLSGLIKEGSFINVFFKVINDLGFMVMRYLPIFFVTGIAFGLSKK
                     EKGWGALGGIVLFIGMHTVISTLLAANGINSDTVTAEAFMASGLGEAEAYSRSSLYGS
                     FLGIFSYDCSIFGAIIAGFVASAVHNKFVDIELPSALSFFSGPRFSMIMMFIASIVLG
                     TAMYFIWPPVGLALSKLGNWIGSSGLLGTFTFGAMDKALLPFGIHHLIAFPIEYTRVG
                     GTMEVGGAIYEGVNNIRLAQMGDPDTLSYITRNFTTGRLLIHFAILPAAALAMYKLAD
                     NANKKKAISILIPAIVTAMLVGVTEPIEYTFLFVAPLLYFVAYVPLAGLTYVFTEMFN
                     VSIMGESFRNMFPNLLQPQKVDALPLLFLIPIFFIVTYIIFTWAIKKFDIKTPGRSSE
                     EVKLYSKKEYRERQSVDAGKTAYNNAVEEEVDDKDTKLVHSIIEGLGGSNNIKNVTNC
                     ATRLRVELNSIDGFYEDGFWVNELGASGVVKKKNSVQVIFGPRVITIASKLKAVLGVD
                     "
     gene            complement(28249..29652)
                     /locus_tag="KR294_001490"
     CDS             complement(28249..29652)
                     /locus_tag="KR294_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBH0239572.1"
                     /translation="MIVNKELIIDYLKSNQENIINDIRSLVEIPSIRDESTTDINQPF
                     GIEIRNAFDKLIQIAKDKDFVVKDFDGYAIHIEYGEGEEVVGVLNHIDVVPIYNKELW
                     KSKPFKVCQKDNYLYGRGVNDNKGPLIGILYALLFLRELNEKPKRKIRLIVGGAEETT
                     WECMEHYFSVNEQPKFAFSPDGNFPIVNGEKGILYFNLRKKIDKDKFRNHNLVDIKSN
                     KEDGFVCDKIEAVFKTNDKKDLVESLAYYTEIEELEEGKVLVRYTGERALSRNPHRSY
                     NCAFSLAKDLEKIKKLNDKGVIIRDILNSYFTDDNHGKKLGIYKEDVDMGVSTICIMS
                     IFLEKNELNMKIDFRYPKGISWEFITNRINEIGKKENLIVDIYKDLKLLYVKPDSELI
                     NKLSNAYKQGFGKEAELFTKGAASYARVLKNGVAFGPTIEGDNPNSHQANENISIDTL
                     YKAIEVYIYALYSLAFQ"
     gene            complement(29916..30407)
                     /locus_tag="KR294_001491"
     CDS             complement(29916..30407)
                     /locus_tag="KR294_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBH0239573.1"
                     /translation="MFNIFKKKENKIEKIYSPFKGNLVNLEDVPDAVFAQKMMGDGVA
                     IIPSEGKLYSPVDGEIVNVFDTKHAIMIKSNDNTNILIHVGLETMSLEGKPFDVKVKA
                     GDKVKAKDLIMEVDLDFITSNDLNIITPVVIMDDADSVKRTVKDRIEPGNVDINSIIM
                     EVE"
     gene            complement(30433..31245)
                     /locus_tag="KR294_001492"
     CDS             complement(30433..31245)
                     /locus_tag="KR294_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBH0239574.1"
                     /translation="MRYKLICTDMDGTLMGKGFEVSEENIKALKEVMEKGIKVALVTG
                     RPYNAMKYFTSVLGDDIYIISTNGTYFKLLGYEYKKVLSKEALKKIYTIGEKYNLSKH
                     FKGCKIVISNNEIGEEHPYRLINSKNKEEDRIEIIENASCETLLEKADNEILKCILFS
                     ENVDSLREAKEEFKKQEDLEVVSSGKINFEVMSKGTSKGIAVKKFCDILGIDSKEVIC
                     IGDNENDISMIKFAGLGIAMGNATDEVKSMADFVTDTNVNDGVAKALRKILS"
     gene            complement(31258..32409)
                     /locus_tag="KR294_001493"
     CDS             complement(31258..32409)
                     /locus_tag="KR294_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HBH0239575.1"
                     /translation="MINFYQPSRINFGQGTLSELPRIIGKYGKKCLLVTTPNVEPLDK
                     LYKRVTLNLIEKGIEVVHFDRVEPNPTVELINEGFELAKKESVDVVLAVGGGSSIDTA
                     KVLALTFGLEKIDWDYMFSTYTNPFKIYDKVSEKELPLIAVSTTSGTGSQVTQAAVIS
                     RGSEKNTIFHQNCFSKECIVDPELMLTLPERITASTAFDAFTHAFESYINPNANDFTE
                     IMSEKSMELVINYLPKVMEDKNNIEYRTKLAVADTLGGSSLANAGAAAPHPLSEIIGG
                     VTHIPHGEALAIVFPKFAEKFYKDNIEKFAKVARMLNQELEKVEDDEAAKTLGNEIES
                     FLKRVGLKTKMSEFNVTKEQLEQITSCPVLGFLPFGKKEDLVEILEKSY"
     gene            32679..33320
                     /locus_tag="KR294_001494"
     CDS             32679..33320
                     /locus_tag="KR294_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldolase"
                     /protein_id="HBH0239576.1"
                     /translation="MKYLIDSANLDEIQKCLKYGFKGITANPSMYLKEKVNFHEFIET
                     CANLNPEILTAEVIGNNLYELINSCDKILNINKNTIIKINFSEVGLELINILNSKGVK
                     TACTLIFNVNQASLAINAGADYLFPFIGRNDENGNDGIKNLTEICNLISINGYNTKVV
                     AASIKNVFHLTQASLCGCDYAAVTYDLFKKASFNQLTIDGANTFERDWSKVNK"
     gene            33346..34890
                     /locus_tag="KR294_001495"
     CDS             33346..34890
                     /locus_tag="KR294_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBH0239577.1"
                     /translation="MNKRLLDIAELLLNSSDYITVDTIAEELKVSNKTIRNDLVILDE
                     WLLEFNLSLDKKTGSGVIILGNEDIKLKVIRDINDKSNCIYAYSPEDRKRYILSKLFI
                     KNSKFRIRDICNELHVSRATVHKDLVVIQNFLQNFKVTLVRKTNNGVYLEGKEKDIRK
                     AIFELATVNKSYTELKEILFSKSNECKDTPSTKIFKELFNYDFEKLSQITLHTLQVEK
                     SNLSDEYYINFLIHIAICIKRISIKRYINLSEGFFRELLEHEYFEKSKILCANLSEAF
                     DVEFIDEEVCYILLHIEGLLKSIKKTTTLEPLKNEEITEYNLSEAIAVHWGSILNLNL
                     KDDLILIKSLANHLKSVLHRINYGFTITNPILNDIKRTFPYTYKAAKESNTVIKQLMN
                     YEVNDDEIGYLALYLISAIDRSKSPLNTILICHCSDGVSNLLVQKLSFEFNQINIVKS
                     IPLSSISFTNFDDVDLILTTAPVDFEHNAELININALLSKNDISRLSTIIKKLYSEKN
                     KILSYK"
     gene            complement(35090..35716)
                     /locus_tag="KR294_001496"
     CDS             complement(35090..35716)
                     /locus_tag="KR294_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBH0239578.1"
                     /translation="MKKEMIKDYLLITISAFLMALAVNFFFAEHTLAPGGITGLSVVL
                     STFLSMPVENISLGISMPLLVMGLLFLGKGFGIKTLYITLMGPLFLKVIPQTHITDNL
                     LVAGVIGGLLVGTAIGIAIIRGCSTGGTDLVAMLINKVIKFLKLPVILFMLDGFIIVA
                     SGIISKNFMISIYSLISLLLIIKTIGFVTTKFGKNTEEINNINNACAQ"
     gene            complement(35851..36567)
                     /locus_tag="KR294_001497"
     CDS             complement(35851..36567)
                     /locus_tag="KR294_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentose-5-phosphate 3-epimerase"
                     /protein_id="HBH0239579.1"
                     /translation="MKHIKIAAGLAHVNYGHISAVVKEAMDAGVDYVHSDAADMHDLK
                     NMQLMGGHQIIEAIRPVTDKPIECHIYTRDCDRLFIEKIAAAGCNLLIIPAEHFLGAP
                     LAYIINYCREFGMKVGLTIGCYTPLCFVDEAIYDIDRLQIVVHGVDETDGKDNWGWRK
                     SAVDLVKRARKMIDEKNPKCELAIDGGLRADNMEPLIECNPDVVILSSAIFKDKDGIT
                     AGVKNCRKAIDKAATKFGLE"
     gene            36993..38207
                     /locus_tag="KR294_001498"
     CDS             36993..38207
                     /locus_tag="KR294_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HBH0239580.1"
                     /translation="MRNCIIAQSGGPTAVINASAVGIYEKNLETKYFDKVYFGINGIE
                     GILNKNIIDSDSLNKDNVLNLKQTPSSGLGSCRYKLADYKINSYDYDRVINILDEYEI
                     DTLFYIGGNDSMDTVMKFSQYCKNTTCKIKFIGIPKTIDNDLLGTDNCPGFGSAAKLI
                     STLIMETYLDFSIYKNNGIFIVETMGRDTGWLAASSSLARLNDTPLVDLIYLPEIDFY
                     EDKFIEDVRKIFKEKNKAYIVASEGIRDKYGNFICEQKTSAHDKFGHSQLGGVSNYLK
                     NLIVSSSITTRVKTLELGVIQRCAMHLASDTDLKQAAEVGAYGIELSKKGYTGVMAII
                     NRTCNNPYKYEVSHTDISKIANKTKYFPKEWINEECNYITDEALNYLYPLIQGKPDIK
                     YKNGLPYFSIIY"
BASE COUNT        12635 a         6774 c         4361 g        14817 t
ORIGIN      
        1 cttcatttaa tgataactat agacagaata aaaaagaata actacataga atctgtcgaa
       61 gtagtaaact acatagataa taataatgat ataagcattt caagagatat atcaaatttt
      121 ttagagtctg aatacaatat aactttaact agtgcagaat tatactactt agtatttcag
      181 ttaacaaaca aaaccacagt cttaaattat catgaaatgg atactaagtc attgccaaat
      241 tatatagatg aacattttgt taaattaact aaaaaaataa ttaaaaatgt atatgactta
      301 tactttatag atttatctga tgatgaattt gttgtaaaat ttactcttca tgtaaaaaat
      361 ttaatcagta gggctaaaaa taatcaagtt ttgagaaatc aaatacctca gaagttaaaa
      421 gattcctacc ctctgatata tgatatatct gtttatattt gtaatcagat tcaaatttta
      481 gaaaacatag aaatagatga agatgaaata tcgtatatat ctcttcatgt aggttcattt
      541 tttgatagac aaaaattact agaagataaa attctctgtg cattaattac tccaaattac
      601 tatgatttac aattcaaaat agtaagagac cttgagaaga gatttaatga atccatagaa
      661 attattcaga ttttttcaga tactcataat cttgattttg acaataaggt agacatggtt
      721 attactactt taccaattag cgatagatgc cctatacctt ttgtttatgt aaatccttac
      781 ctaaatagaa aggattatga taatattcaa agtaaattta ttcagattaa agatagaaaa
      841 aatatactta ctgtacaaaa tcatttagaa atgtacttta gtgaatcttt gtttatgaaa
      901 aatatatatt tagatagtgc taaagattat ataagattta tgggaaatat tctgtacgaa
      961 aataaatatg tcaaacccaa ttatatagat gatgttctta taagagaaaa aatgtcttca
     1021 actgcattta ataacaatgt agcaattcct catagcatga aaatggatgc tttaaaaacc
     1081 ggagtatgtt taattgttaa cgataaacca gttaaatggg gtgaggaaaa agttcaaatt
     1141 atagctatga tacctataaa tgaaaaagaa aaagaaaagt tcaattacat atttgaaagc
     1201 tttattgaaa tattatctga gtggaataat gttaaagaac ttactaaggc agataactat
     1261 agtagtttta tgaatagaat agcttatctt attcaaaata tctaaatcaa ttaatttatt
     1321 tccaatatat gtttcttaag ttattaacat aaaatagata agctgtcaca ctaaaaagtc
     1381 taaattaata tgtgacagct ttttacctaa tataccttgt tttaatacta catatttttt
     1441 gactgttgta tactagttat aagattgaat atttgtgttg ttgtagctgt catattctca
     1501 ctagcagttg ctttatccat tgcttcttct attgtcatag ctctatttac tatagaaaaa
     1561 taagcatcta taccctcttc attacattta actgcatctt ctgttgtggc tccagccaaa
     1621 cctattactt ttaccccata tttttttgcc agttttgcaa ctcctattgg agccttgccc
     1681 atagcagttt gattgtccaa tctaccttca ccagttatga caaaatctgc atcttttaac
     1741 tcttcctcta atttaatttc ttctaatatt atttttattc cagattctaa ttttgaattt
     1801 aaaaatgcta aaaaagcaaa acctaatcct cctgctgctc ctgctccttc tacattagct
     1861 acatctttac ttaagtaatt tttaactact ttggaaaaat ttctaagccc attatctaac
     1921 tcctcaatta tttctgatgt tgcacctttt tgagacccgt atatgtatgc agctccattt
     1981 ttcccaaaca gcggattatt tacatcacag gctattttaa acttacattc atctaattcc
     2041 tttaatctat tttctatttt tatatgtctt atttcattta aaacttttcc acctaatcct
     2101 actaacttgt tattttcatc ataaaactca aaccctaagg cttgaagcat acctatccca
     2161 gcatcattag tagcacttcc acctatccca actataaaat ttctatagcc tttatttatt
     2221 gcttctttta ttatttcccc aacaccataa gttgtagtgt ataaaggatt tctaagttca
     2281 gtcggaacca atgttagtcc tgatgcttga gctatttcta ttattgctgt acttgtattt
     2341 tttaataatc catatgttgc atccactttt ttagctattg gtccagtaac ttctatagta
     2401 tcttttttac cattcatccc ttgaactaag gcatctactg tcccttcacc accatcagca
     2461 agtggcaata tctttacttg cgcatcttct ttaaccttca atatcccctt ttttattgca
     2521 tttcctgcct ctattgaaga taagcttcct ttcaaagaat ctatagaaat taatattttc
     2581 atatttatct actccttttt attactcctt attttaaaca tataatttta taagcttaat
     2641 ttatctttta ttttatactc tacatctctc tttgtataca acttatacca ttaatattct
     2701 tttatcttat aaaaagggag tgtctcaaaa taaatttctt agttcatgag acactctttt
     2761 tgtataaaat caaatatatg tttattattt caacaatgat aaggaggatt atctctattt
     2821 taagataatt cctttttagc actatttaac cagtatagtt ttaacttggt tcattaagca
     2881 ctctacattt acagagttat tatctattga tatagattct aattcttttt catttaggtt
     2941 aatccattta gctgttttaa tatttttgtt aaatactatg ttagctgatt ttgtttcttc
     3001 tttagaattg taaaatctaa ctactaatgc ctcttgtttt tcagcctttt ttacaacact
     3061 taacacaagg tccttattag tttccttaag taaactatat gaataatcta cttctatttc
     3121 tgattgattc aatttcatag cattatatgg cattttatta taagtttgta tttttgttaa
     3181 atactcttta gccatatttg caacatttgc ttctagtgta gatttttcat gagtaactat
     3241 tgctaagtct atttttatat ctcctatcat ttgagaatct ggagtaggca actttattcc
     3301 tgatggacga cctgggcgtc ttgccatttc ttctttacct aggaatccta cacttctaaa
     3361 taatgttata gctattgtgt caaatttttc ccctactatt tcaaactctc ttgtactgtt
     3421 tgtaagaaca gctactccat gctctttgtc agacaatcca acgaatgtta gcattggata
     3481 tatagaatct ggtctttcac tccattcttc ctgttgccaa acttccatag catcatcata
     3541 cacacttctc tttatatgtc caaactgatt atcagacaca gaaaactttg aagctatatt
     3601 tgttggtata taagttctaa ccctacaatc tcttgcttgg ttatttatgt tgaatactac
     3661 atctattata gctttatcat ttggaacatt tataactata tcaaagtcaa taaatgaatc
     3721 tgctctatta ttttttctag cttgtatatc ttttggtact tttaatctat aatttatctt
     3781 tatctcatta ttaaatctat ttttctttat agtggaattt gctactatat tatcgttaaa
     3841 tattaatttc tcatttggaa gtggtgaaaa atcatactca tctccttcat ctcctccatt
     3901 ttccatcaat aatacatttt caaaagtttt atttaatttt ttatcaaata tctttaatgt
     3961 cccgttttca ttaacttgaa tagtataaaa gtcattatct accatgtcac atacttcata
     4021 agctttttct aacatatgtt caacttcttt tatcatatac gccttatacc ccattgcagg
     4081 tattttatct ttaaagttta ttgtatatac cataaatgaa tcatagtttc cataatgaac
     4141 aatttgacgg tctattaatc ctgcatctat tacttcttta tgtaccactt caaaatccaa
     4201 cttattatta tctttatcaa atatttcaaa tgctttcatt ttagttataa cttgagcgct
     4261 tactatttca ttcctatcgt aaggcattaa gttaaatgct actaacttat ctaaagccat
     4321 ttcacaactc attgcatcaa ctattcttct tttgtaaaat gttattaatt ggtctacttt
     4381 ttcctcagct aagaaaaatc tattcattat ttcatggtga actttatctg aacaacaaca
     4441 tccaatgctg tcatgagcat gatttttcat tatttctttc caaattaact ctattaatcc
     4501 atgatgatat tcaaatccta gagaatatgc aatagaagct agtggctcca atatgttggt
     4561 tatctttgat tctattctag catttgctga ttttatatcc attcttgttg agaatatact
     4621 tctatgaacc ctcatatatt tcccatctaa aaattcccct tttattgtat ctatatcctc
     4681 atttttttct agctctttaa atatgttttc atatctactt aagaaaaatt ttctctctgg
     4741 ataacattct tttaatttat atataacttc aaatatattc ttttgaattg gcatttggtc
     4801 atgtccattt ggaagtatta tatggtcagt agttgcaccc ttatcaagaa ccggtaaata
     4861 tttatccatt cttgttctta gctcatcttc attcattggt agatattttc ctattgcata
     4921 acctaatgga agtatttgaa ccaaaacaga agacccatca tcactcttcc aattaaactc
     4981 tgttttatta gttccttttc tttcagaaca tcctctccaa aacattgagt attttatatc
     5041 aaacccattt agtatttgtg gcatttgagc actttgacca aatgaatctg gtaaatatcc
     5101 tattttcata tattctccaa attcatcaca atcttttatt ccatatagta aatttctaag
     5161 tatggattct ccaccaacta ccatttcatc agtttgagta taccaaggac ctattattag
     5221 ccttccttct tgaactaatt tttttattct ctccttacat tcaggcttaa ctgctaaata
     5281 atcttctaat atagcagttt gaccatccat cacataatat ggatagttat gattattttc
     5341 taacatatcc attatttctt ccatattatt tacaagtaat attctagatt cctcagttga
     5401 gaagtaccat tctctatccc aatgcatatg aggaactatg tgtacatttt ttttcattgc
     5461 ttatcctcca aaacttatct gataatattt tctgtctaat taaaaatcca ataaaaatac
     5521 tactgagttt acaaaatttt ttaatattta ttttatcact ataattaaac ctttgattta
     5581 aatatctaat aacgtatctt ttaatgtatc tttctttgat ttttttgttt cctagttatt
     5641 attaataata ctgctgatat tatagctcca agtactgccg caaagaacca tattgatgct
     5701 ataataaatc ctgacatact tccctctaaa agcgccaatg agaatatccc cgctccaggc
     5761 acttgaagac ctatattgaa gaatgctact atagacccag ttatggctga accagctacc
     5821 aatgatggta taacacggat tgggtcctct atcataaatg gtattgcacc ttcagttatt
     5881 ccagccaatc ctaatatcca agtttgcttt cctatttcct tttctgattc tgaaaataaa
     5941 tctctgccta aaacagtagc tattgtaact ccaaaagctg aaaccatctt aactgatgca
     6001 aatattgcat aaggtataaa atttccactt gctattgctc ctattgcaaa tgtataggct
     6061 gctttattta ttggtccacc taagtcaaat gaaaccatag ctcctattat tgcacctagt
     6121 agtattgcat ttactccagt catcccattt aaccaattta taagaccatt gttaagtgct
     6181 gctacaggct ttcctactac aaataacatc aataaaccta ctaccaaaga accaactact
     6241 ggatataccc aaaaacttac gaatccagct aatgtgcctt tggctggtat attcttcttt
     6301 aaaaatttta ctatataacc agcaagtaaa cctcctaaca tacctccaag aaatccacta
     6361 cctattaaat cagctgctag acctgctgca aatcctggtc caagacctgg tttttcagct
     6421 agtgagtaag acatatatgc tgataatact ggaaccatca atgtacctaa catacctcca
     6481 gaaagctttc ttaattgcca taaccaagaa ccttcttgat tgtatagttc ttgtagacca
     6541 aatgcttgag atgctaatac tgcaaatgca agtatcatac ctcctgccac aataagtggt
     6601 attatatgag atactcctgt aagtattgct gattttacat cttttttcca tgatgatttt
     6661 tcacaatatg atatatcaga tgatttttct atataatcac ctttaccttg tttttgtgct
     6721 acttctaaag cttcgtatat tatttctttt gctcttttta gtggagctgc tactgacgtt
     6781 tttatgtttg gcaaatgttc aaatctttct gtatttttag gtgctacatc tgttgcatat
     6841 attattgcat ctgccctttt tattatatct ggtgtatgag ggtccaccat accattagct
     6901 ccttgctttt ctacatacac atccacaccg atttctttac cagctttaat taatgcttct
     6961 gctgacatat atgtatgtgc tatacctgca gggcatgctg ttattgctaa tataattttt
     7021 tttgattcat tttgaatcct aatctcttct tttatttgtt ctttcttttc ttttatatct
     7081 aagttattaa ataactcttt cttagttttt gaatttaaca acatattcat ataatcttca
     7141 tttgacagtc tagtaactaa ctcagaaagt atttgtatgt gtgtatttcc accttcattt
     7201 tctggtactg ctattaaaaa tattatctct actttattat ttgggtctac gctttcccaa
     7261 ttttctattg gtgtctctaa ggtcatagct gcaaatgcag cttctttaac tgacttagat
     7321 tttccatgag gaattgcaag ccctctttca aaacctgttg gagataaagt ttctctgtac
     7381 attacagctt ctaaatattc ctcataagat gttaacttgc cttcatcata tagctttctt
     7441 gctaagaact ttattgcgtc tttctttgtt tttatttttt gttttaaaaa aacaaggttt
     7501 tcatttgtga ttttcttaaa ttccaaaatt acgccctcct taaatcattt aatgctatga
     7561 atatagcata aaataaatta tgaaaatgtt tttttgaaat tatacacaca atttcttctt
     7621 aaaaaataaa gatttgtgta tttatacaca aatctctatc ttaaccagta ttgctctatt
     7681 attgctctca taatcatcat aattggaacc ttatctgata tattgtaccc atttacttgt
     7741 ttaattgttg aatagcaata taaacttata tctgcaattt gttgcaattg attttcacat
     7801 atatgtgtta gagctactac cttacaaccc ttattaactg ctgtctttgc tacttctata
     7861 acttctttcg tttctccact taaactaagt gcaaaaaaca tatcttgttc acctaatttt
     7921 cctatatcat gaagtacttc atgtctttga ctatagtaag ttatattatc atgcccacct
     7981 ctaatttctt ttactaatat ctcacataaa ggaatgtttt gacctattcc ataaactata
     8041 atactcctag atttttgaat tatatctgct actttattta ttttttcata atctattagc
     8101 tctaatgtct tttttatatc tgattcaaaa ccattttttg gctctttatc ctcatttttt
     8161 aactcttctt ttaaattatt ttttagttga gagaaaccat catactccat ttttttacat
     8221 agcctaacta tggtatttgg gacagtaaaa aatttatctg ctaaagattg tattgataat
     8281 tttactattt cttctttgtt ttttctcata tattcaatta tcatgtcttc tgtatctgta
     8341 aatttatact catatttttt tgctctttca taaaattcca tagtttctcc tccatctatt
     8401 ttattattca taagtaaaat tcaaaaatat tagctaaaat tttcgttaat ataattataa
     8461 tttaatattt ttaatttatt aatgcatact actcttttta ttatacataa aaaatgtgta
     8521 cttcctatat tgatagagat gattcaagtt tttattttga tacatctcta tcaatatttt
     8581 tttagaaaat acacattttt ttcaaatact tatttttaat taaaacttta ggtaatctat
     8641 tctttatata taattattag acttgaaaat atctttaaaa tcaaccaatt caatattatt
     8701 tctttttaac cacattttaa cttccttatc acatagcatt gcatgttcat atactctctc
     8761 ttgaataaga gaagatgatt ttataagact ataatctata aatcctggat gagtaaccat
     8821 caatgttata tctttatcta aatttatata tttttcttca aataatttaa caaaagattt
     8881 atttaacttg taaaaatcat tctgaggata tttacttggc atgctaatac atgaatccaa
     8941 ataataggga caacttggta taccgtattc ttttgcagca tcacacattg ctgatattga
     9001 tacatcttct tctataccat gtatatcaat atactcaggc aatttactca tatacaactt
     9061 gtaagtttca atttgagcac aaacttcttc atatacttct tcataattaa aaacctcttt
     9121 acctgtcagt agttgcgttc ttcttatttt gctagaaaca aattttccac cttcatctaa
     9181 caaattcttt atcttaatat gttctttgca acaaggttct cctattacta aattaacatg
     9241 taaaccaaaa catacatcat cattttttac catttctata gcttgtcttg aaaaaggcat
     9301 attcaccatg attccagcac ttgtaacaat accgttctta taagaagata ttatccctag
     9361 tgtaacacct tctgaatatc ctatatcatc tgccctaact actagtttct tcattttatg
     9421 cgtctgcctg ctttctcaac tcatcaagtt gcatttccat ctcatccttt actttaacaa
     9481 catccgttcc tatgatgatt tgaactgatg tattactcaa tttaattacc cctttggctc
     9541 ctgttttttt aatattatca tcattcaaaa tagtagcatc cttcacttct aaacgtaatc
     9601 tcgtcataca attattaaga gtcactatat tttcataacc accacaattt ttaattatct
     9661 gtttagccat atatgaaaaa ttaccatgag aaagttttaa attcttttct ttttcactaa
     9721 ctttatcacc tatctctatc tcaacttcac gtcctggtgt ttgcacatta tcttttatta
     9781 ttatatattt aaatgttaca taatataata caaagaatac aactcctaca ggtataacta
     9841 accacgcttt atctccataa ctaaaactta agacatagtc aattatactt gctccattaa
     9901 atgaacccaa gcgaacaccc agtaaatata gtacaactcc acctagacca gaataaaaag
     9961 aatgaattat atataacttt ggagatgcaa ataaaaacga aaattctatt ggttcagtta
    10021 ctgttgccat aaaagaagtc aatgctccag cggtcattgc accttttact tcttgcttct
    10081 ttttatcttg tgctgtttta tatatagcat aagaaatagc aggtattgaa aacatcataa
    10141 ttatgtaaaa tcctgtccag aagaatcctg catttgggtc tcctgccata aatctaggaa
    10201 tttctcctct tataacttct cctgttgatg ttgtatattc acccatttca aataatatgt
    10261 aagcatttaa aacttgatgt aacccagttg gtattagtgc acggttacag aataaaaaca
    10321 agaatattcc tattgcacca gctcctccca accaaaaacc aaattgattc attgcagctt
    10381 gtggatatat ccataataaa ctaaatatat atgataaaat taaagcaacc actggtgata
    10441 gtgtaattac acatttttct cctgcaaaga agcttaaaaa tgctggaact ttaactttat
    10501 atgttttatt gtaagtccat gctatacaag ctccaacaat tatcccacca aatacacctg
    10561 catttaatgt atcattcaat aactctaaat ttgacttaaa tatcatatat gcaactacgg
    10621 ctgcaaccat tacacttgtc ttgtctttag actttgagta ggcactagct gctcctaata
    10681 aaaataagta gtccacattt gaaaatacta tattagatat attagatata gctggcacat
    10741 tgagcatatt tggaccaaat aataatccta atatacctgc tgctggcatt acagctattg
    10801 gcactagcat agtctttcct aaaagtgaca gttgttgcat cattttgttt aagaacctct
    10861 tcatatccaa tcccctttct atttcggttt aattttttgt gaaaacgatt tattcacatt
    10921 ttatatttta aatattatat ttgtttaaac aaattgtcaa tattttttat tcattttatt
    10981 tttatcattt agtttaacat ataaatcctt ttaagtgtat tgctatatct agtctatttt
    11041 tttaattcat tttttttatt ttaaaaatat gtttaaccat gtatttgaaa caacccacaa
    11101 aataattcta ttttgtcctt tttatggttg atatgattct attttcacta tacatgtcta
    11161 aacacatttg atataatttg ttcatatcag ttcaataata ttactaaaga cctttaagga
    11221 gggatagggg tatatggcta aaaataaatt ttcagagata tatgaagtat tgaaagagga
    11281 aatacttgat ggtaaatata caagtaatat gatgctgcct actgaacttc aacttattga
    11341 aaggttttca tgtagcagaa acactgtacg tagagcaatt tctcaattaa acacagaagg
    11401 atatgttcaa agtataaaag gcaagggtgt tgtagtgtta gaaaatagtt gttctaatga
    11461 tttttttcta aatatgcaca atttcaaagg tgtagaatcg attgtagaag ataaaaaggt
    11521 taatactgct actagtgttc tccacttcag caaaatctta attgataata agttatctaa
    11581 aaagacaggt tttaaagttg gtagtgaagt atattacctt cacagactaa gatatattga
    11641 taacatacct aaaattctcg acattaacta ttttctatgt agtatagtta aagaccttga
    11701 tgtttctata gcacaaggct ctatttataa atatatagaa gagtgtctag gtacaaaaat
    11761 tgtttcatcc agaaagatat ttaaaattga aaaagctaca gagcttgagt taaaaacgct
    11821 acctctaaat gattataatt gtgttggtgt tattaaaaat agtgtatata ctgatgatgg
    11881 aaagcttttt gaatatactg aatcaaagca tacacctgaa acatttgtat tcatggatgt
    11941 tactcaaaga tattaaaaaa attatgttta attaaacata atttttttac gtttagacac
    12001 tttatcccat actaacctca ctattctata tacaattatg tgtttataca aataattatt
    12061 tattgtatat tttagcttta atattagttt aatgcttgac aatttgttta aacatattat
    12121 aattaactta taaattacag gaggtatcaa ttatgaaaaa ttggtggaaa aaagcaactg
    12181 tctatcaaat atatccaaaa agtttcaaag atagcaacaa tgatggtata ggtgatataa
    12241 atggtattat agaaaaatta gattatctgt attatttagg tgttgattta ttatggttga
    12301 ctcctatgta cgtttctcct caaagagata atggatatga tatagaagat tattataata
    12361 tagacccaaa atatgggaca atgagtgact ttgaaaaact cttaaaagaa gctcataaaa
    12421 gagacataaa aataatgatg gatatggtcc taaaccatac atctactgaa cataaatggt
    12481 ttaaagaatc taaaaaaagc aaagacaatc catatcgtga ttattatttc tggaaagatg
    12541 ctaaacctga tggttctgtt cctaataact ggatatccag atttagtgga actgcttgga
    12601 aatatgatga aaccactaac caatattatt tacatttatt tgaagaaact caagctgatt
    12661 taaattggga aaatgaaaag gttcgtgaag aatgttacaa aatactagaa ttttgggctg
    12721 ataaaggtat tgatggtttt cgtttagatg tagtcaacct actctccaaa acacctggat
    12781 tacctgatga ccctataaca ggaccaaaag gagatggaag aactcactac gctgatggtc
    12841 ctcgtataca cgaatattta cataatatga atcaaaaagt tttcaaacct aaaaatatag
    12901 ttactgtagg tgaaatgtca tctactacac ctgaagagtg tatcaactat actagagaaa
    12961 atcgagaaga actatctatg gtttttagct tccatcatat gaaaacagat tataaaggag
    13021 gcgcaaaatg gactaatgaa atgttctctc tggataaatt aaaaaaagca caatctgact
    13081 ttcaatataa aatgtatgaa ggaaaaggat ggaatgctct attttactct aatcacgacc
    13141 aacctagagc tttatctaga tttggagatg atagattttt tcgtcaagaa agtgctaaga
    13201 tgttagccat aacactattt ggtctacaag gtactacata catatatcaa ggtgaagaaa
    13261 taggtatgac aaatgcctac tttactaaaa tagatgaata tgatgatgct gaaagtaaga
    13321 atgcatacta tcatatgatt aaatctggta ttgatgaaaa ggaggcattg cttatacttc
    13381 aacaaaaatc cagagataat gcccgtactc ctatgcaatg ggataatact atttataagg
    13441 ggttttctaa tcataaaccg tggttaaaag ttaataatga caatattagt gtagaaaatg
    13501 agcttaatga ttctcgttca gtattttata cttatcaaag attaatcaaa tatcgtaaac
    13561 aatatgatat ttttacagaa ggtacttata gattgttaga tgaaaatcat aaaaatctat
    13621 ttgtttatga aagagagtat aaaaaccaaa atcttcttgt tataagtaat ttcactcatg
    13681 ataatgtagt atataaatta cctgaaactt atttgaataa attaaactac acaatacttg
    13741 aaaccaatta cactagagat ataattgaaa ataaaatgga aataaaacct tacgaaagta
    13801 taatgatata ttataaataa agttatttat gtaaaaatag gtataacacc ctggtgttat
    13861 accaatttta ctaaattcaa agtaatgttt atagaatatc tatagattac aataattatt
    13921 tgacttctac atcattatat ttctttgaat atactttagt catatagaaa tatataggaa
    13981 ctacaattat catcccacct aatccccaaa ctatcttcat aggttcatca atacctgctt
    14041 ttatcagtaa taatatactt ataataactg caaatattgg tataattgct cctccaggta
    14101 ttctaaaatt tacatcttta ccagcatact tctttctcaa tattagtaca gctaaacatg
    14161 taggaatata ttgaataaat ctagatacaa cacttatttg agataatgtt gtgaatgaac
    14221 ccgaccatgc tattagtaaa gttcctatga cagatactat aattgctata taaggagctc
    14281 catttttatt agtttgtctt atagacttag gcattaatcc ttgttcaacc aaagcagcag
    14341 cagaccttgg tgtaaatatg gatgatgcaa tatttatacc tccaacagat actatagttc
    14401 ctattgtaat tatataccca cctataggac ctaacatctt aatggcagca tctgcaacag
    14461 gagtagctga ccctgctaag ccattaccca acacccctat acttattccc agtataagca
    14521 tatatattac tgatactaca aacattacca ttaccaatgc tttaggtaca tttttcttag
    14581 ggttctccat atcttttgct gcaacagcta aagattcaaa tcctgtaaaa gcataaaata
    14641 aagttataga tactgctaca aaagctgatg acgcactttg acctttttgt attattacaa
    14701 atggggtaaa attagaaccc tttataaaga ataatcctac agctataaat aaaactattg
    14761 gtaataattt tcctatagtc atgatattat ttaagtgctt agattgtttc attcccataa
    14821 aatttataat cccaagccct acaactaata taccaattat tatattttta ataagtggtt
    14881 ctgctgcttg tggccataca gatgatagtg ttacagcaaa gaaatttgcc atagtagccc
    14941 aagcaatcat actaactatc cacttcataa atccaacttc aaatccaaca aaatctccaa
    15001 atgcctcttt tgcataaaga tagggccctc catcagtatc aaaccaacta cctgcttcag
    15061 caaaacataa agcaatagaa acagctaaaa gcatacaaaa aactaatact aatatacttg
    15121 ctggacctat atctgtataa gcatcaccag gtaacccgaa tatacctgac cctattattg
    15181 cattgattcc taatagtaca atactccaaa aacctaactt aatgcctttt tccattgtta
    15241 ttccccccaa agccaactta atatatttgt attttttatt tagatgcttc tttaactatt
    15301 gccataaata tttttttcat attatcataa tctctagtca tcatttctgg atgccattgt
    15361 atccctatta caaactcact tccttccttt tctatagctt caattaaacc gtctttagat
    15421 gtagctgaaa caatatatcc cggtgctact ttgttgacaa ctaagtgatg aaaactatta
    15481 actaaaactt ctttttctcc tagtatttca tataattttg tcccctcctt tatctgtact
    15541 gtatgtgtag gtacattaga tagatgttgc tgattgtgtt taatataagc accttcaatt
    15601 aaagataaat cttgatacaa actacctcct tcagttacat ttataatttg ttctcctcta
    15661 catataccta aaactggttt tttcatatct aaagcatgtt ttaataattt catatcaaaa
    15721 ctatctctct ttggtgatat tgcccccaac ttattatgag gttcttcttt ccatatgagt
    15781 ggatttacat cttgtccccc agatagtata agcgcatcta tattagatac ctgctccttt
    15841 ataatctcat catcatatac aatcggtaca atatatggta tagctttaca cataactact
    15901 gattgtatat aatcattatt tacataagcc ctttcatagc caggaaacat tcctccttca
    15961 tcaattagta aattacctga tattcctatt attggatatt tctttttagc caatttcttc
    16021 accccttaac ttatttgtga acaataaaaa atgctacttc tcttaaagag caagtagcat
    16081 accaagattt tatttatttg aacattataa tttattttag aaatactttt tttgaatacg
    16141 agtaatataa ataactttat ttacttatat tttattttaa tcctgtttag tttgactttt
    16201 ttaaattgtt ttaagtacaa ctaataggta aaataggcat ttagattttc ctttttatca
    16261 acctattaaa tactgtttaa tatatttttt ccccttctat ttaattcact tccctttcta
    16321 ccagattcac atattatcaa atccagctct tttaacatat taagtattcc tcttacctca
    16381 ccttctgtta tattgtagcc taattcattt attgaattaa caataccatt tctacctata
    16441 tttttattaa gattattggc attttttaaa cactccatta ctaactttac tttctctata
    16501 gatgttctat cctttaatat gcttatttct ttactaaaat cttcagttat atttaataag
    16561 ttatgaggta aatcatttat taaaataaca tcctcagaac tcataatgtt aatatacata
    16621 gcagtatttt ttaattctct tatattacct ggccattcat atgcattaat aatgtcttga
    16681 acatcttgac taattgctct cttccttttc ataaaatgct ttaacataac ttctatatct
    16741 tcttttcgct ctcttaaagg tggtatattt atgggcaata catttatcct atagtataaa
    16801 tctgctctaa atctatctcc ttttatcatt tctaataaat ttttatttgt agccgcaatt
    16861 actctaacat ctatatctat tacattttct cctccaaccc tcattacttg attctcttgt
    16921 aatactctaa gtaatttgct ttgtaagtat ataggcatgt ctcctatttc atccaaaaat
    16981 atagttccat tgttagcctg ttcaaataat ccttttttac ctccttttaa agctcctgta
    17041 aaagcacctt cttcatatcc aaaaagttca ctttcaagta aattttctgg catagctgca
    17101 cagtttattg ctataaatgg ctgactatgt cttggtgatg cattatgaat agactgagcc
    17161 atgagttctt ttcctgttcc actttctccc gttataagaa ttgtataatc agattcagct
    17221 attttcatac ctaatttctt agttctttcc atcttcgttg aaactgtttt tatatcatca
    17281 aaagtatatc tagcaacttg tcccttttct ctaagcttct ttgataggtt ttgctccaat
    17341 tttcttatgt aagttatttc ttgaatacaa aaataatatc cagtaaccct tccaaaactc
    17401 tctatattat acttatttac gtttaagtac ttattattaa attttataac ttcatcatgt
    17461 gccttactca aactaaaaat ctttttaata ttctcattct ctaattcatc tatatttttc
    17521 cctataatat tactttgaat atctagtata tcccttaaac tattattaca aataattatg
    17581 tttcccttat ctgataccat tgccatacct aagtttgata aatttattat ggaatttagt
    17641 tcatctgctt ttatagtaag ttctttgtat ttagtattta ttcctgaata taaactaatt
    17701 atttcatctg tatacttaat tagcctctca gtaatttctt tatcatccag tttgagtttt
    17761 gctattattt gaataaacgt tgaactatca atatacctat ggcctaaatc aataacttct
    17821 tctatatatt ttggaactaa acttgactct cctggcgtta tagctatctt aatatttcta
    17881 tattcttcat tgggattgta tggtataaaa ttcaaatgat ttattcctat attgtataaa
    17941 ttagatattg tttccaatac agtatgctta ttatcgttta ctactaatac atctattcct
    18001 tctggcaatg aaaataactt atatatatcc ttttgcttta tgctcctatt tatagttatt
    18061 atctttgaga catcttccac atattttttt atttttaata ctctatcatc tatcattacc
    18121 aatattatgt catcttttat taattccttc tctgttattt tatttaaata ataatttttt
    18181 atcattactt tatctttaaa gatcatttct agatttttat ttaagaaaca ttctaattta
    18241 gacaacccat cagttactac tgctattgtt ttcatttgat tactcctttt aaaatatact
    18301 ctactctttt ataatataca tttgattttc actttaataa cacaaaaaat tgtacattta
    18361 gtatactaac atattccttt attagtttta tgtccataaa tatcatagtt gcaatatcta
    18421 tcatatttct taaacttcta taaagcaaaa attgtgccaa attaataatt ttcttaattt
    18481 tattctaaag ttcctcaata gtatttacag acttagcact tatagcttat aagtctttat
    18541 attattaatc tatttttata ggttaattgt acaaatcata tatcactttt acctattaaa
    18601 tgcattataa aaaattgtat ttataaacac tatttactac tcttctaagt acaaacagta
    18661 tctacatact ataacctttc accattagat tctattactt gtttatacca gtcaaaactc
    18721 tttttcttaa tcctagacaa gtctccactt ccatcatcat acttatccac gtatataaac
    18781 ccatatctct tggccatctc accagtagat gcacttacta aatctataca tccccatgga
    18841 gtatatccaa ataaatcaac gccatcttct acagcttcct tcatttgctc tatatgtgct
    18901 tttaaatact ctatacgata gtcatcattt atcactccat tagattcttt tttatcataa
    18961 gctcctaaac cattttcaac taccatcata ggtattctat atctatcata aatttcattt
    19021 agtgcatatc taagcccttc agggtctatt tgccatcccc attcactaga cttaagatat
    19081 ggatttttca ctccacctaa tatgttgcca cttgtattat cttctttaga atcactactt
    19141 acacatgtag acatataata actaaatgta taaaaatcta cacaaccttc ttttaaaatt
    19201 tctaaatctc ctttttccat ttttatttca atattatttt ctccaaaata tctattcata
    19261 taagttggat attcgccacg cacttgtaca tctccacaga aataattcat tactctacta
    19321 tctctttgag ttttaactgc atcatctgga ttacaagtat aaggatacat tgttgcaaat
    19381 atttgcatac atccaacttg ataatttgaa tctatttcat gagctaactt aacagcctta
    19441 gcacttgcta caaattgatg atgtaaccct tgaaaacgaa gttgaggtat atctacttgg
    19501 tttataaaat ctgtagtccc ttcatttaat attccttgtg ataagtagcc tcccataggc
    19561 attgtagctg aatttatttc attaaatgtc agccaatatt ttacttttcc tttatatctt
    19621 ttaaatattg tttcacagta attcatatac aagtctatta catctcttga aacccatcca
    19681 ttgtatttct ctgttattgc aaatggtatt tcatagtgag atattgttat taatggttct
    19741 atattatatt ttaaacattc atctatcaca ttttcataaa atttaagtcc tgcttcattt
    19801 ggttctttct ccattccagt tggaaatatt ctagtccatg ctattgaaaa tctaaatacc
    19861 ttaaatccca tttctgcaaa taaagctata tcttctttgt atctgtgata aaaatctatt
    19921 gcttcatgac ttggataaaa tgttcctttt tctataactc tcgttattct tttacttact
    19981 ttttgagaac ctccagtaca catatctgaa caagaaggac ctttcccatc taaattccat
    20041 gctccttcac attgatttgc tgctgttgct ccaccccata aaaaatcttt tctaagtgcc
    20101 ataattctac ctccaataat ttatttatag taactttatt ttaaaataaa aatacatata
    20161 tataattctt aattaataga actctctttt acgctaaaac agttatcaat ttctgactat
    20221 tatttacatg cttttgtgta ttttctacaa tatccacata atcagaataa ttagtaacaa
    20281 ctactggtgt ttctaagcaa tatccttctt ttgaaatact ttctatgtca aaagttatta
    20341 atgtctgacc ttttttaatc ttatcccctt gattaacaaa agatttgaaa tatttacctt
    20401 ccaactgaat agtatttaac cctatatgta tcaatagttc acaaccatta tcagatataa
    20461 ttcctattgc atgttttgtt ggaaataaag tcattacagt cccatcaaat ggtgccacta
    20521 cttttccttc tttaggtgtt attgctacac cttttcccaa tatacctgtt gaaaacgctg
    20581 catcttgtat ctgctccaaa gcctttactt caccttttat tgggctatat actacttctc
    20641 ttttgttttt ttctataacg ccttgcccat tatcatcttt agaaatttct actatagcat
    20701 catctttcca aaaaaataat gttaaaacaa atcctactac aatagctact attattgcta
    20761 ttatagttgc ataaacacct ttcatatctc cagttgttgg atttatataa ttaggtatac
    20821 caaatattcc aagtccaccc attacataac tttttacatt cattatcccc attacagctc
    20881 ctgccacagc accacctaca caactatata tgaatggtgt ttttcttggt aaagttattc
    20941 catatattgc aggctctgtt acaccacata tccctgaaat aactgcaggt atacacagct
    21001 cttttatctt cttatctttt aatttaaagt acattgctgc tactactgct gtttgtgcaa
    21061 aagatggtac aaatactccc actaatattg tgtcaaaccc catagtcata aggtttgaca
    21121 tagctattgg tactaatccc caatgtagac caaatattac aagcacttgc cacaataaac
    21181 cagttaatgc accacataaa attggtgaaa agttaaataa agctaaaaat ccatttccaa
    21241 ctatattaga agcataggta gctataggcc ctataaccat aaatcccaat ggtaaagaaa
    21301 ctaataaaac tgccattggt acaaagaaat tctttactac atctggtatt attttagcaa
    21361 acactttctc caacttagct gctaataata ctattaaaat tactggtact actgttgaag
    21421 tgtagttcat tgctattact ggtaatccta agaaagttat atatactggt gattcaaata
    21481 ttgttccagt aaatagattg tataaaggtt gacctgtaga tgctagagta tctaattgaa
    21541 tacctgaata gcataaaact gcacctataa gcattccaat aaatggtttt aatttgaatt
    21601 tcttagcagc tgtatatcca agaattattg gcatatactg gaacattgca tctccaattg
    21661 catttaacat aatatatgca ccatcagttt ctccatacaa acccaatgct gtaaatactg
    21721 cattaaatcc ttttatcata ccagcagcac acagaactcc taatattggt tgaaaaactc
    21781 ctgatattat gtctataaac ttattaagta atccttttgg cgcatctgag tctgaattat
    21841 ctattgtatc tcctcctaat ccagccaaat cgcacacaac ttcataaaca tctggaacat
    21901 gattaccaat aactacttgg tattgacctg cacttttcat tacagtaact ataccatcca
    21961 ttttttttag cacatcatca tttgctattg actcatcttt taatttaaaa cgtagcctcg
    22021 ttatacagtg agataaactg ctaatattat cctttcctcc tacattcgca atgatttctt
    22081 ttgatagttg ttcatacttt ctcatttttt ctcctccatt ttctttttga aatatgaagg
    22141 tttggccaac ttaatgtcac cacccaatat atataaacct aattattagg atttatatcc
    22201 gacttaatac ttttacttac cactctttca acgtgaatag ttaagtataa tttttcctca
    22261 tctgttaaat cgtagttgta ttttttatgt ataaattcat ccaacttttc tatgaattta
    22321 taagcatttt tatatttaac ttttattaca tttaataaat catcttcatt attttcatgt
    22381 aaattattac taacaattcg ttctgcaaaa tactttaagt gagtaataaa tctatgataa
    22441 taaactgaat cttcatcaaa tactattctg taatggtatt taaccatatt tgaaatttct
    22501 tgtattattt gtgtaatctc atatatagtt tttatacttt gatccatttg tgcattaact
    22561 atatgcagtg ctataaatcc agcttcatct tctgatagtc taatttcaaa ttttttttct
    22621 atataatcca atgcctctaa ccctatttta aattcactct tataaaatct ttttatatcc
    22681 caaagtaata cattttttac acttactcct tcacgagctc tttctattgc agtatacata
    22741 tggtctgtta aagaaatata aatactatca tttaatcttt tccctagttt ttctttagca
    22801 tataaaatta tttcatctga taattccata tatcttatag gaatatctgc tattagttct
    22861 ttaaatttat cagatatatt tgggtctgaa agtttgaata tcttatcaat tttatccttt
    22921 gatatatgct ctcctgtacg ttttttataa gctaaacctc tccccataac tactatttcc
    22981 ttatgatttt catcagttgt aataattaca ttattattga gtattttttc aataatcatt
    23041 gtgatgcccc ctttattagc attaagttaa aataaatctt ttttaattat ttagaatatt
    23101 taaaatgtaa tttattacat aaaaaaaaac ctatttatta cacattaaat agactcccat
    23161 gagtcctgag taataaatag gtttagcttg tatttaaaca atcactatcc gtttgtattt
    23221 tattttaatt attatttatt atatgttagc aaatttattt tttagtgtca actttttctc
    23281 aatattttaa ttttaaataa attatataaa ttgaatcttc aaagtactat ttttatcaat
    23341 aaacaaaata aaaaaggtat tactttcttt aagtaatacc catttatttc taatttaagt
    23401 ggtttttctt aatctcatca agtagtccat cttctaaata aatttctaat gcacatccta
    23461 ccattgcctt tactgctttg tgaagtttat cataagcttc ctcagaattt gcataattta
    23521 gaaattcttt ttcatgaaca tataccattg gacttatatc taaggctatt tctgtataca
    23581 tagtagggca aacttgactt acattaccta tatctgtaga acctactgga ccatctttac
    23641 cttctaatat atctgttata cctgcctcaa tcaaattatt ctttgttatc ttttgaagta
    23701 ctttgttatt tattatgttg tcaaaagaat tttcaaagta tctataagaa agcttagctc
    23761 ctgtcattaa ctctgcacct tttgcacagt ttataacttt tttagttact tcatctaaat
    23821 aacttctttc agcagctctt acgaaaaact tacaagctgc tttttctgga actatatttg
    23881 gagcctctcc tccatttgaa actataccat gtattctaac atctgatttt acatgttgtc
    23941 ttagtgcatt tatcccagca aaagtaagtt gtactgcatc tagtgcattg actcccatat
    24001 gagggtgact agctgcatgt gctgataccc cttcaaaact aaactctaat gaatctatcg
    24061 ccaaagcctt acagtttata ttattaaaag cttctatatg catttgataa cttacatcaa
    24121 catcatcaaa agctcctgcc ttaactaaat cacattttcc tcctgttgtt tcttcagctg
    24181 gtgttcctat tagtacaatt tttcctttaa aattttcttt taacttactt aatactatac
    24241 aagctcctag tgtagatgct gcaatccagt tatgtccaca agcatgagct ggttctttat
    24301 tttctccata tccaggaagt gcatcatact cagctaaaaa tgctatggta ggtccatcat
    24361 tatctcctaa ttcagctcta aaagcagtct ccatattaca atatggataa actgtatcaa
    24421 atccatattc cttcattttt tctactaagt attttgatga tatgtattct tcttccccta
    24481 attcaggatt gttaaatata aaattacaaa cttcttcaat ttcttttcca agttcattct
    24541 ctatctcata agctctcttc tttatactct ctatcataat ttacctccta ctagaatcct
    24601 agatataatc ctattgtcaa aaatgccatt acaagaattg ttaatactac cattaaagga
    24661 attacgaatc taacccactt tgaccaagga atattggcta ctgctagtgc tcccattaaa
    24721 acacctgatg taggtgttat caagttagtt acacctatac caaattgata agctgtaact
    24781 atcatttgtc ttgatacatc tactaagtcg ccaagtggtg caagtacagg tattgtaagt
    24841 gatgcaagcc ctgatgctga tggtattaaa aatgctatta atccttctat taagaaagtt
    24901 aaatttataa atatagtttt tggtaatcca tttaataaat ttgctgcaga atttaaaatt
    24961 gtatctatta taaatccatt ttctgctatt attacaattc cacgtgcaaa tgctatacac
    25021 aatcctgctg tcattaaatc tcctgctcca cttataaatg aattaactat atcatcttgt
    25081 ttaagacctg atgctatacc tgatattata cctatagctg taaatatcat tgcaatttca
    25141 gttatatacc atcccaactt taaaactcca tatatcataa tcgccatacc tattgtgaaa
    25201 attgctatta ccatggcttc tctttttgta aattccttta tatttgtatc actattaacc
    25261 attgattctt gatttagtga tatatcgtgt actaaagatt ttttagggtc ttttttaact
    25321 ttattggcat acatcataac aaatcctata gatatagcca tatatattat aaacataaca
    25381 actctaaact ctattccaga acctggtgct atttgtgata atgcttgtgc tattcctaca
    25441 gagaaaggat tcgtagtagc tgctccaaat ccagctgttg ctcctataaa tactgtggcc
    25501 actgctgtca atgaatcata tcccatactg gtcataagtg gaataaatat catataaaaa
    25561 ggtagtgtct cttcactcat tccaaacgtc gtcccaccta gtccaaatag aatcattgaa
    25621 atcggtatta ttaaaaattg aaacttcttc attttattta cagtatgagc tataacagct
    25681 tctatagctc ctgttttatt aactatccca aaagctcctc caactattaa aacaaatcca
    25741 actacttcag cagcatctat aaacccgttt ataggtgctg taaatacatc agtaattcct
    25801 tgtggatttg atggtgcttt ttcataagtt ccagctacaa caactgacct tccgtctata
    25861 tctactcttt caaaatttcc acttggcact atccaagtaa gaattgccat taacactatt
    25921 agcaaaaata ttattgtaag tgtctgtggc atagtaaact ttttcttttt taaactgctc
    25981 atttttaatc tccccacttt ttaaattaaa tattttatta ttgcatccct ttatcctatt
    26041 ttgtatagat gtaaaaaagc tcaacatgga tacatgttga gctaaatgtg ctaaatacaa
    26101 catacctgca tcttcccttt atcttgttta agatagctct ccatcaaaat tcgggataat
    26161 tttgatgaca gtactgtacc tattaaatac agtcccagca ctagcttcgg acactagcac
    26221 ttcggcactt actcctttta tattgcctca ttggtttcca acctcttcaa tattaatctt
    26281 agtaaatgca acctctacct caatctgttt gttagatgag gtaattctta ttaattttta
    26341 ttaattcaaa gtaattgtag cataatatgt cgagattgta aatattttca gtataataat
    26401 tcttacttta tgatttcatt ccatttttca caaataattt tttctccata taatttaaat
    26461 actgtagtat attttaaata cacacaaact ttccacaaat tttaaattat tataatacct
    26521 ttataataaa aaataaaagc tatgtaaact tatcaattta cacagcttta tatacattaa
    26581 tctactccaa gtacagcttt aagctttgat gctattgtaa taactcgtgg accaaatata
    26641 acttgaactg agtttttctt tttaacaact ccacttgcac ccaattcatt tacccagaag
    26701 ccatcttcat agaatccatc aattgaattt agctctaccc taagtctagt tgcacagttt
    26761 gtaacatttt ttatattatt acttcctcct aaaccttcta ttatagaatg tacaagcttt
    26821 gtatctttat catctacttc ctcttctact gcattgttgt atgctgtttt accagcatct
    26881 acagattgtc tttctctata ttctttctta ctataaagct taacttcttc tgaacttctt
    26941 cctggtgttt ttatatcaaa cttcttgatt gcccatgtaa atattatata agtaactata
    27001 aaaaatattg gtatcaaaaa taataatggt aacgcatcca ctttttgtgg ttgtaataaa
    27061 ttaggaaaca tatttctaaa tgattctccc attatagaaa cattaaacat ttctgtaaat
    27121 acatacgtca atcctgccag tggtacatat gctacaaaat acaataatgg tgcaacaaat
    27181 aggaatgtat actctattgg ttccgttacc cctaccaaca tggctgttac tattgctggt
    27241 atcaatatac ttattgcttt tttcttatta gcattatcag ccaacttata catagctaaa
    27301 gctgctgctg gtaatattgc aaaatgtatt aataaacgac ctgttgtgaa gttacgagtt
    27361 atataagata gtgtatctgg gtctcccatt tgagctaatc ttatattatt aacaccctcg
    27421 taaattgctc cacctacttc cattgttcca cctactcttg tatattctat agggaatgca
    27481 attaagtgat gtataccaaa tggtaataat gctttatcca ttgctccaaa agtaaatgtt
    27541 cctaataatc cactagaacc tatccaatta ccaagtttag ataatgccaa ccctactggt
    27601 ggccatataa agtacattgc tgtacccaat actattgatg ctataaacat cataatcatt
    27661 gaaaatcttg gacctgagaa aaaagataat gcactaggaa gttctatgtc aacaaatttg
    27721 ttatgtactg cactagctac aaatccagct attatagctc caaatatact acaatcatat
    27781 gaaaagattc ctaagaaaga accatataaa gaacttcgac tatatgcttc tgcctctcct
    27841 aatccagatg ccataaacgc ttctgctgta actgtatctg aatttatacc atttgctgct
    27901 aacaatgtac ttataactgt gtgcattcct ataaataaaa caattcctcc taatgcaccc
    27961 catccttttt cctttttaga taatccaaag gctatacctg taacaaagaa tattggtaag
    28021 tatctcatta ccataaatcc taaatcgttt attactttaa agaatacatt tataaatgac
    28081 ccttctttta ttagtccgct aagccctaat gcagaaacgt tttccatatt tgcaaaagct
    28141 gaccctagtc ctataaatac tcctgctaca acaagtaata taacaggtat catcattgct
    28201 ccagaaagta cttgtaattt atccttcata gtattatttc ctccattttt attgaaatgc
    28261 caggctatat aatgcatata tatatacttc tattgctttg tataatgtat ctatacttat
    28321 attttcattt gcctgatgtg aatttggatt atccccctct attgtgggtc caaatgcaac
    28381 tccatttttt aacactcttg cataagatgc agctcctttt gtaaaaagtt cggcttcttt
    28441 tccaaaacct tgtttatatg catttgataa tttatttatt aattcactat ctggttttac
    28501 atacagtaat tttaaatcct tatatatatc aactattaaa ttttcttttt ttccaatttc
    28561 attaattcta ttagttataa actcccaact tataccctta ggatatctaa agtctatttt
    28621 catattcaat tcatttttct ctaagaagat actcattata catattgtag aaactcccat
    28681 atctacatct tctttatata tccctaattt ttttccatga ttatcatctg taaagtatga
    28741 atttaaaata tcccttatta taacgccttt atcatttagt tttttaattt tctctaaatc
    28801 ttttgctaaa ctaaatgcac agttatatga cctgtgtgga tttctcgata aagccctttc
    28861 tcctgtatat cttactaata ctttaccttc ttctagttct tctatctctg tataataagc
    28921 taatgattct actaaatctt tcttatcatt agttttaaaa acagcctcaa ttttgtcaca
    28981 tacaaatcca tcttctttgt ttgactttat atcaactaaa ttgtgatttc taaatttatc
    29041 tttatctatt ttctttctta gattgaagta taaaatacct ttttctccat ttactattgg
    29101 gaagtttcca tctggagaaa atgcaaattt tggctgttca ttgacactaa agtaatgctc
    29161 catacattcc caagtcgtct cttcagctcc acccactatc aatctaatct ttctcttcgg
    29221 cttttcatta agttctctta agaaaagtaa tgcatataaa atccctatca aaggtccttt
    29281 gttgtcatta actcctctac cataaagata gttatctttt tgacatactt taaaaggttt
    29341 actcttccaa agttctttat tatatattgg caccacatct atatgattaa gcacccctac
    29401 tacttcttct ccttctccat attctatatg aattgcatat ccatcaaagt cttttacaac
    29461 aaaatctttg tcttttgcta tttgaataag cttatcgaag gcatttctta tttctatccc
    29521 aaatggttga tttatatctg ttgtactttc atctctaatt gaaggtattt caactaaact
    29581 tctaatatca tttatgatat tttcttgatt ggattttaaa taatcaataa ttagttcttt
    29641 gtttactatc atcttaatta tttatcaccc ctttatatta attttacaaa gcatttcagt
    29701 tcatatctac attataaatt ttgaatatta ttttttcaat atttcaaata cttctctaag
    29761 ttaccataat gatacggtaa acaatcaaca gattatgaca aaatcatact atacctatta
    29821 ctaatatttt aacttatcta ttacgtcttt tttaatgtaa gtttattcca aaaatacata
    29881 aaaaaagatg tagccttagc tacaccttct tatatctatt caacttccat tattatgcta
    29941 ttaatatcta catttccagg ttctatccta tcttttactg ttctcttaac agaatcagca
    30001 tcatccatta taactacagg agttattata tttaaatcat ttgacgttat aaaatctaaa
    30061 tctacttcca ttattaaatc tttagctttt accttatctc ctgcctttac cttaacatca
    30121 aacggctttc cttctagtga cattgtctct aaacctacat gtattaatat atttgtatta
    30181 tcattactct taatcattat tgcatgcttt gtatcaaata cattgactat ttcaccatca
    30241 acaggagaat ataacttacc ttcacttggt attattgcta ctccatctcc catcatcttt
    30301 tgggcaaaaa ctgcatctgg aacatcttct aagttcacta aatttccctt aaaagggcta
    30361 tatattttct caatcttatt ttcttttttc ttaaatatat taaacataac acactctcca
    30421 cattataaaa ttttatgata atatttttct taaagctttt gctacaccat catttacatt
    30481 agtatcagtt acaaaatctg ccatagattt tacttcatct gtagcatttc ccatagcaat
    30541 accaagacct gcaaatttaa tcatggatat atcattttca ttatcaccta tacaaataac
    30601 ttctttgcta tctataccta atatatcaca aaatttttta actgcaatac cttttgaagt
    30661 acctttactc ataacttcaa agtttatctt tccagaactt actacttcta aatcttcttg
    30721 ttttttaaat tcttcctttg cttctctcaa agaatctacg ttttctgaga aaagtataca
    30781 ttttaaaatt tcattatcag ctttttctaa taaagtttca caacttgcat tttctattat
    30841 ttcaattctg tcttcttctt tatttttact atttattaat ctatatggat gttcttcacc
    30901 tatttcattg ttggatataa ctattttaca gcctttaaaa tgtttgctta aattatactt
    30961 ttcacctatt gtatagattt tctttagagc ttctttgctc aaaaccttct tatactcata
    31021 tcccagtaat ttaaaatatg tcccattagt tgatataata tatatatcat cccctaaaac
    31081 acttgtaaaa tatttcatag cattataagg tcttcccgta actaaggcta ccttgatacc
    31141 cttttccatg acttctttta gtgctttaat attttcttct gatacttcaa atcctttacc
    31201 catcaaagta ccatccatat cagtacaaat taatttatat cgcatttgta tcacatccta
    31261 gtaagatttt tctaatattt caacaaggtc ttctttcttt ccaaaaggta aaaatcctaa
    31321 aactggacag cttgttattt gttctaattg ttcctttgtt acattaaact cagacatttt
    31381 tgtcttaagt cccactctct ttaaaaaact ttctatttca tttcctaaag ttttagctgc
    31441 ttcatcatct tccacttttt ctaattcttg gtttagcatt ctcgctactt tggcaaattt
    31501 ctctatatta tccttataga acttttctgc aaattttggg aacactatag ccaaagcctc
    31561 accatgagga atatgtgtaa ctcctcctat tatttcactt agtggatgtg gtgctgctgc
    31621 tccagcattt gccagtgaac ttcctcctaa tgtatctgct actgctaact ttgttctgta
    31681 ttctatatta tttttatctt ccattacttt aggtagatag ttaatgacta attccataga
    31741 tttttcagac attatctctg taaaatcatt agcatttgga tttatataac tttcaaatgc
    31801 atgagtaaaa gcatcaaatg ctgttgatgc agtaattctc tctggcagag ttaacataag
    31861 ctctgggtca actatacatt cttttgagaa acaattttga tgaaatattg tatttttctc
    31921 gcttcctctc gatattactg ctgcttgtgt aacttggctt cctgttccag aagtagttga
    31981 tacagctatt aatggtaatt ctttttcact taccttatcg tatattttaa atggatttgt
    32041 atatgtacta aacatataat cccaatctat cttttctaaa ccaaaagtca atgctaatac
    32101 ttttgcagta tctatacttg aacctcctcc aacagctaaa acaacatcta cagattcttt
    32161 tttagctaat tcaaaccctt catttattaa ttctacagtt gggtttggct ctactctatc
    32221 aaagtgtaca acttctatac ctttttctat taaattcaat gtaactcttt tatataactt
    32281 gtctaatggc tctacatttg gagtagtaac taacaaacat ttctttccat attttcctat
    32341 tattctaggt aattcactta aagttccttg tccaaaattt attcttgatg gttgataaaa
    32401 gttaatcata tttttcctcc cttaaattat tgccttcata ttcaaattat acatatcata
    32461 ggatttttaa ggcaatacct tcactgttaa ctcttattta ctaaagctta tggcaattat
    32521 tagacaatca atgttttatt attaccatat cattatgtaa attttattaa gtacccatgt
    32581 tataatttta taatcaatct tattgtataa ttgacttaat aataaaaata gagtatatac
    32641 acttttttat gacaaatagc ttaaaggaga attaaattat gaaatatttg atagacagtg
    32701 ctaatcttga tgaaattcaa aagtgtttaa agtatggatt taagggaata acagctaatc
    32761 catctatgta tcttaaagag aaagtaaact tccatgaatt tattgagaca tgtgctaatt
    32821 taaatccaga aatattaact gctgaagtca ttggaaataa tttatacgaa ttaattaatt
    32881 catgtgataa gatattaaat ataaataaaa acactataat aaaaataaat ttctctgaag
    32941 ttggcttaga acttataaac atattaaata gtaaaggtgt aaaaactgca tgtaccttga
    33001 ttttcaatgt aaatcaagca tcattagcta taaatgcagg tgctgattac ctattccctt
    33061 ttataggtag aaatgatgaa aatgggaatg atggtataaa aaaccttaca gaaatatgta
    33121 accttatatc aataaatgga tataatacta aagttgttgc agcttctatt aaaaatgtat
    33181 tccacttaac tcaagcatct ctttgtggat gtgattatgc agctgtaaca tatgatttat
    33241 ttaaaaaagc ttcttttaac cagcttacaa tagatggtgc caatactttt gaaagagatt
    33301 ggtccaaggt taataaatag taactaagat ttaggagggt ttgcattgaa caaaagatta
    33361 ttagatattg ctgaattatt actcaacagc tcagactata ttactgtaga tactattgcc
    33421 gaagaattaa aagttagtaa taaaactatt cgtaatgacc ttgttatttt agatgaatgg
    33481 cttttagagt ttaatttatc cctagataaa aaaactggtt caggggttat tattctaggt
    33541 aatgaagata taaaacttaa agttattaga gatatcaatg ataaatcaaa ttgtatatat
    33601 gcatactctc ctgaagatag aaaaaggtat attctaagta aattatttat taaaaattct
    33661 aagtttagga ttcgtgatat ttgcaatgaa ctacatgtta gtagagctac tgtgcataaa
    33721 gacttggtag ttattcaaaa ttttttgcaa aactttaaag tgactctagt tagaaaaacc
    33781 aataatggag tatatttaga gggaaaagag aaagatattc gaaaagcaat ttttgaactt
    33841 gctacggtta ataaaagtta tactgaactt aaagaaatat tattctcgaa atctaatgaa
    33901 tgcaaagata ccccttcaac aaaaatattt aaggagctat ttaactatga ttttgagaaa
    33961 ttatctcaaa tcactctaca caccttacaa gtagaaaaaa gtaaccttag tgatgagtat
    34021 tatataaact tcttaataca tatagctata tgtattaaaa gaatttcaat taaaagatat
    34081 attaacttat ctgaaggttt ttttagagaa ttattagaac atgaatactt tgaaaaatca
    34141 aaaattttat gtgctaacct aagtgaagct tttgacgtag aatttattga tgaagaggtc
    34201 tgttatatcc ttcttcatat agaaggatta cttaaatcaa taaagaaaac tactactctt
    34261 gaacctctta aaaatgaaga aattacagag tataatctat ctgaagcaat agctgttcat
    34321 tggggaagta tactaaattt aaacttaaag gatgatttaa tattaataaa gtctcttgct
    34381 aatcacctta aatcagttct acacagaata aactatgggt ttactattac aaatcccata
    34441 ttaaatgata taaagagaac atttccttat acttataagg ctgctaaaga gtctaatact
    34501 gttatcaaac agttgatgaa ttatgaagtc aatgatgacg aaataggata tcttgcttta
    34561 tatttaatat cagcaataga tagaagcaaa tctcccctta atactatttt aatatgtcac
    34621 tgtagtgatg gtgtatctaa tttattagtc caaaagttaa gttttgaatt taatcagatt
    34681 aatatagtta aatctatacc tctatcttct atttcattta cgaactttga tgatgtggac
    34741 ttaatactaa ccactgctcc tgtagacttt gaacataatg ctgaactgat aaatataaat
    34801 gctcttttaa gtaagaatga tatttctaga cttagtacaa ttataaaaaa actatattct
    34861 gaaaaaaata aaatattatc ttataaataa acaaaaatag gcttgtctca acatagagat
    34921 aaacctattt ttcattgtct aaatgataaa aatatatttg atttcataga aaaagtgcct
    34981 catgaactaa aaaattcatt ttgagacacc tccatttttt atatttaagc tttttattta
    35041 agcttttata ttttttaaac ttttatattt aaagtaaatt ttattatttt tattgagcac
    35101 aagcattatt tatattatta atttcttcag tattcttacc aaactttgta gttacaaatc
    35161 ctattgtttt tattatgagt aataaagata tcaatgaata tatagatatc ataaaattct
    35221 tacttattat tccagacgct actattataa atccatctag cataaataat ataactggca
    35281 acttcagaaa cttaattacc ttattaataa gcattgcaac taaatcagtt ccaccagtac
    35341 tacagcccct tattattgct atccctatag cagttcctac caataaccca cctatcactc
    35401 ctgctactaa tagattgtca gttatgtgag tttgtggtat tacttttaag aataatgggc
    35461 ccataagagt tatatataat gtttttattc caaaaccttt ccctaaaaat aataatccca
    35521 ttactaaaag tggcatagat attcctaatg atatattctc aacaggcatt gataagaatg
    35581 tgctaagtac gactgataat cctgttatcc ctcctggagc taatgtatgt tctgcaaaga
    35641 aaaaattaac tgctaatgcc attaaaaatg ctgatattgt tatcagtaaa taatctttta
    35701 tcatttcttt tttcatttaa taacctccta tgattatatt atttcagtat aaaaaatcaa
    35761 ttaaattagt ctagcttcct gtagtttttc ataaaattaa tgcttcctta aaacattaag
    35821 aaagcatctc ttttatcata gtttattatc ttattctaaa ccaaactttg tagctgcttt
    35881 atctatagct tttctacaat tcttaacacc tgctgttata ccatctttat ccttgaatat
    35941 tgctgaagat aatattacaa cgtctggatt acattctatt aatggctcca tattgtctgc
    36001 tcttagtcca ccatctattg ctaattcaca cttaggattc ttttcgtcta tcatttttct
    36061 agctcttttt actaaatcaa cagcactctt tctccatccc cagttatctt ttccatcagt
    36121 ttcatcaaca ccatgaacga ctatttgcaa tctatctata tcatatatag cttcatcaac
    36181 aaaacataat ggtgtgtaac atccaattgt taatcctact ttcataccaa attctctaca
    36241 gtaatttatt atgtatgcaa gaggagcacc taaaaaatgt tctgctggta ttatcaacaa
    36301 gttacatcct gctgctgcta ttttttctat aaataatcta tcacaatctc ttgtgtatat
    36361 atggcattct attggtttat ctgtcactgg tcttattgct tctattattt gatgaccacc
    36421 cataagttgc atatttttta agtcatgcat atctgctgca tctgaatgca cgtagtctac
    36481 acctgcatcc attgcttctt taactacggc tgatatatga ccgtaattta catgtgctaa
    36541 tcctgctgct atttttatgt gtttcatatt tgtatacctc catattttac tttaattagt
    36601 attaaatatt agtttttgat atttttttaa tattttttaa tccagtatta cttttattta
    36661 gcattacttt tattgctgta tatatttctt ttatgaactt attctgcttt tgttaactgt
    36721 gaacttattt tgctttgtaa attaatatta cactgatata ttttttttca caacactttg
    36781 actactcctt aaaagtacct ttatattgtg gtaaattata gacattaatt gtatataaaa
    36841 agttagtttt ttaccacatt cttatggcat ttattgtcta tactaactca attgatatag
    36901 ctagttcatt taatatataa tcagactata aatataaatt tactcgataa aaagtaccat
    36961 tcataacaat attaatgaaa gggagatgta aaatgagaaa ctgtattatt gcccaatctg
    37021 gaggccctac agctgttatc aatgcttctg cagttggtat ttatgaaaaa aatttagaaa
    37081 ctaaatactt tgataaagta tattttggta tcaatgggat tgaaggtata ttaaacaaaa
    37141 atataataga ttcagactcc ttaaacaaag ataatgtatt aaatttaaag caaacacctt
    37201 cgtctggtct tggttcttgt agatacaaac tggctgatta taaaataaat tcttatgatt
    37261 atgatagagt tataaatata ctagatgaat atgaaataga tacattattt tatataggcg
    37321 gaaatgattc tatggacaca gtgatgaaat tttctcaata ctgcaaaaac actacttgta
    37381 aaataaaatt tataggtatt cctaaaacaa tagataatga tttattagga actgacaact
    37441 gtcctggatt tggttctgct gcaaagctta tttctacact aataatggaa acatacttag
    37501 atttttctat atacaaaaat aatggtatat ttatagtaga aactatgggt agagatactg
    37561 gatggttagc agcttcttct tcactagcta gacttaatga tactccactt gttgatttaa
    37621 tataccttcc agaaattgat ttctatgaag ataagtttat agaagatgtt agaaaaatat
    37681 ttaaagaaaa aaataaggct tatatagttg cgtcagaagg tataagggat aaatacggca
    37741 actttatatg cgaacaaaaa acttctgctc atgataaatt tggtcattcc caattaggtg
    37801 gagtaagcaa ctatctaaag aatcttatag tatcatcatc aattacaaca agagtaaaaa
    37861 ccttagaact tggtgtaata caaagatgtg ctatgcattt agcttcagat actgatttaa
    37921 aacaagcagc tgaagttggt gcatatggga tagaactatc taaaaaagga tatacaggag
    37981 ttatggctat cattaataga acatgcaata atccttataa gtatgaagtt agtcatactg
    38041 atatttctaa aatagctaac aagacaaaat attttcctaa agagtggata aatgaagaat
    38101 gtaattatat aactgatgaa gccctaaatt atctatatcc acttattcaa ggtaaaccag
    38161 atatcaaata taaaaatgga ctaccttatt tttcaattat ttactaggaa attattataa
    38221 tttgatatac actcaattct atcgctctta aatacctaag tggctgttaa ataaaattat
    38281 aaattgttat atgacagtca cttaatcgtt taattattta actgtttagt tttttaattt
    38341 tttaatcttt tttaatacta atacgatttg ttgtaataat atctcacacc cattttcatt
    38401 ttggatagat tataattagt tagacaataa atattttgtc atgatattat tatatatagt
    38461 gatacaaata gaaatacttt tatcatggct agaaaaacaa agattacaca aaggatttaa
    38521 aaatcaaaca acttcaatta aaataaatgg ttaaaataac ttctaaatca actactataa
    38581 acaataa
//
LOCUS       DAEPKC010000028        38126 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.028, whole genome shotgun sequence.
ACCESSION   DAEPKC010000028 DAEPKC010000000
VERSION     DAEPKC010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 38126)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38126)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38126
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.028"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..1477
                     /locus_tag="KR294_001499"
     CDS             <1..1477
                     /locus_tag="KR294_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBH0239581.1"
                     /translation="NMSLCVEISALYQTKTDVIALVEEVSFFKTLKNKALVSRANYIF
                     GRVYLYLFNNFIKSMEYLIECLKLAQENNLYSIEAFCKCIISLCYLESGNNVEAIKYI
                     NNVLDVAHSNNSISVTERVSIKIDLIWAYLKEDMNKEAEVILLKTIKLMKVVEGVYKD
                     YLYSFIFLYSAEIELKKDNCSFEKVNTYLILSKNIYKSFGDVFIYNSKLDYIYKLYGD
                     LYIKFGNIDEGISCYIKGLNLVKKSSLNLRKISIFYGLIANGYELKKDFKLAIEYYKS
                     MDWYSDRWEKNNSYKTSQAIHKQYELRQKQESLRLLVDDNKKLENDILKDGLTKLYNR
                     RYLEQQLDLFNETRDKNMVAILVDIDCFKSYNDNYGHLAGDKVIVKVTDIIRSVFIDI
                     TEHIIRYGGEEILILVDSIESIGVEEIDNIELYIKRVFKLLEFEGIEHIYSKIKNYIT
                     ISAGVSIKRCRSRKDVEILIEDADKNLYKSKKAGRNQYIII"
     gene            1485..3485
                     /locus_tag="KR294_001500"
     CDS             1485..3485
                     /locus_tag="KR294_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH0239582.1"
                     /translation="MILLRKKIGIIASDIELKERIEELYREDVENGTIIIDILNLDLM
                     ENQGRILVEKGAQAIIGRGGGYSLVIDTVNVPVIPMNMKSTDLLRAIEIAKKYSKKVV
                     LILGDNEVSFDYVGWRNVISTEITEEWFESKYEIRSKVVKYIDQKDEIVIVGGGLACS
                     FARQYGIDSVFATASDESIREAVEYCKKLLDTLGEEKFNNEVLRNILDGIKDGVIAID
                     SNGSIILYNESAKNMLKVERKCALNKYILDVFPKMEWMLDCLHEKEDVEDRKIRNINN
                     LIVNTRTTLIKVDNSTYGVLGIIQDITKLQNLERKIRFDLNQKGLYARYTFDDFLFKD
                     KLTKEFIEEAKKIGKSDYTTLLYGESGSGKEIIAHSIHNISKRKDRPFVAINCATIAE
                     NLLESELFGYEEGAFTGARKGGKRGLFELAHGGTLFLDEINSLSFNIQTKLLRVIEER
                     QIMRIGSDYIIPLDIRIIAATNESLTEKIVMGTFRADLFYRLSSLEINIPPLRDRRED
                     IIPLFNNFVNEVLKDDGLNGINSIDENFVLTKDEMDKLYNYSWPGNVRELKTIAQKYV
                     VTGKIKLRQDRDFKTKKLLPNSEVDKFNSETTASVEVQDESINISKINDGKISIDIKE
                     VNKYVEEKIISMLFAQGLSKNEVAQVLGISRTSLWKKYNKNI"
     gene            3747..5006
                     /locus_tag="KR294_001501"
     CDS             3747..5006
                     /locus_tag="KR294_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBH0239583.1"
                     /translation="MSQSMVGKHAMWPKENDVIFSISGRAQAAEKAFGMDNVINATIG
                     ALMDDSGKLITMKTVYEEYKALDNCEIGAYAALEGQPDYLEAVKKVFFRDYLPEGHIR
                     VLASPGGSGAIKLAVWNYTNEGDEVLTSDWFWSPYVSIAEEANRKVVNYQLFDENRRF
                     NFESFKEKFVNIAEKQGRVFTIINTPAHNPTGYSVADDEWDKILDLSKEVAKDKDKKI
                     IFFVDSAYIDFAGDDDVCRKFFKKFSNLPENVLVLVGFSMSKGFTAYGMRMGAIICIS
                     SSEDVAEEFHYSCVHSCRANWSNCNRSAMAVLSNIVNDPKKFKEYEDEKEIYKNMLTR
                     RADVFVKEAERVGLEILPYIAGFFVSIPCDNPKEVCEELTKHNLFAVPLKMGLRFAVC
                     AVSEDKCKKAPSIIKEALESLEVKINN"
     gene            5067..6854
                     /gene="iorA"
                     /locus_tag="KR294_001502"
     CDS             5067..6854
                     /gene="iorA"
                     /locus_tag="KR294_001502"
                     /EC_number="1.2.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indolepyruvate ferredoxin oxidoreductase subunit
                     alpha"
                     /protein_id="HBH0239584.1"
                     /translation="MKQLMTGNEAIARGAYEAGVKYASAYPGTPSTEILENIATYKDA
                     IVAEWAPNEKVALEAAIGGSIAGARTMASMKHVGLNVAADPIFTYAYTGVNGGMVLIT
                     ADEPGMHSSQNEQDNRMYAKFAKIPLFEPSTSQEAKDMIKEAFEVSEKYDTPVLYRVT
                     TRLCHSKGLVECYDREEVEIKEYVKNAKKMVTVPANAQIRRGVVEERMEILKKFSNET
                     DLNYYEINDTKIGVIASGMCCNFAKEVFGKNASYMKLGFTNPLPYEKIKEFAEKVDKI
                     YVIEENDPFIEEQIKAYGIDCIGKDVIPPYGEMTPDVLRKAIFGKTNDTIEYKSELVT
                     PRPPSFCAGCPHRGFFYELGKRKNLIVGGDIGCYTLGFAPPYNGIDYVVCMGSAFGTA
                     HGAQKVLNMKDDNEKRLVGVLGDSTFFHTGINGLLDVVYNRGNSISVILDNRITGMTG
                     HQENPGSGYTLQGAKTKEVDIEGLVKACGIEHVRVINPNNLKEVNEALDWALAIEDEP
                     SVIITRWPCVLKKFSKEDIEEFNNPFKTKCKVDHDKCIGCKLCLKTGCPALSFDKENK
                     LSNIDRNQCVGCGVCAQVCPKQAIVKEEK"
     gene            6856..7431
                     /locus_tag="KR294_001503"
     CDS             6856..7431
                     /locus_tag="KR294_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indolepyruvate oxidoreductase subunit beta"
                     /protein_id="HBH0239585.1"
                     /translation="MTKSILLVGVGGQGTILASKLLTMGLMEAGYDVKMSEIHGMSQR
                     GGSVSSQVRYGDCVHSPVIEIGGADILVSFEKMEALRWFNYLKPEGKALVNNHRIDSM
                     TVLIGGAEYQESDIDAELSRLNAKVINAADKAEELGNSKIMNVILLGCLVKSMQLESI
                     DWEKIISENVKPKFVELNIKAFHEGMEMVSK"
     gene            7484..8554
                     /gene="buk"
                     /locus_tag="KR294_001504"
     CDS             7484..8554
                     /gene="buk"
                     /locus_tag="KR294_001504"
                     /EC_number="2.7.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="butyrate kinase"
                     /protein_id="HBH0239586.1"
                     /translation="MTYRILAINPGSTSTKIAVYDGEEQILVKTIDHPAEEIAKYNTI
                     QDQFEMRKEAVLNILKENSIDLKSLSAIVGRGGVLPPVKSGAYLVNEEMIDVLRHRPV
                     LEHASNLGAVVAHAISEPLGINSYIYDSVAVDELIDVARISGLCGMDRSSAGHALNTR
                     AMALKYAKDKGKDYKSLNLIVAHIGGGVSIYLHEKGRMVDMLSDDEGPFSPERSGRVP
                     ATKLVAACYSGQYSEREMTKKIRGKGGIVSYLNTVDAREVEKMIAEGNEEAKIIYEAM
                     AYQLAKGIGELATVVDGKVDAIIITGGIAYSEMFTSMVKKKVEFIAPVEIMAGENELE
                     SLAFGTLRVLNGEEEARIYSEN"
     gene            8772..9473
                     /locus_tag="KR294_001505"
     CDS             8772..9473
                     /locus_tag="KR294_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239587.1"
                     /translation="MGKISLKSMIRLFSGFFIFAISSVLMINAHVGLMPWDVLHQGLS
                     IKLGITIGQASIMVGVVIVILDAVFGENIGWGTLLNMTFIGIFIDLVIFSGVIPHASN
                     TYIGVFMVVIGIILAAIASFLYLGVCLGSGPRDGLMIALQKKTNKSVRLVRTILEILA
                     LVVGWLLGGSVGIGTLVSALGLGYVLQIVFRIFKFDTKLLKHRFIIDDIREWKEKKSN
                     EHKCKSSIVIKNEQN"
     gene            9533..10039
                     /locus_tag="KR294_001506"
     CDS             9533..10039
                     /locus_tag="KR294_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HBH0239588.1"
                     /translation="MELWDLYNADGIKTGNVIKRGNSIEEGYYHLAVEVWILNSNSQI
                     LIQKRSKSKKTLPNMWGMTTGCIVSGEDSLEGAIREAKEEIGIDITKDEMKVFRSMIH
                     EDTLWDVYLVKKEYDISKAILQEEEVSDIKWVSTDEIRQLLKEGLFFEYPEIYELLYE
                     IDNNKLNI"
     gene            10214..11236
                     /locus_tag="KR294_001507"
     CDS             10214..11236
                     /locus_tag="KR294_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBH0239589.1"
                     /translation="MEDNKGLARDSSKYKIVSISVVVIILITFWYMLNMVLLTFIMTF
                     IFYNLLVATRKRIKKFSSLNIPDSLIIIVLYALFAILLVLISYAVVPIIIVQLTELSR
                     VFSDFDVNQFAQSLGPKLYPIVSKLDFNKYISQAGLLIASTATKVGSFGVNILLAFLL
                     SLLLLLEKNEIKNFGDKLSDSKISFIYNSLVFFGKSFVKNFGEVMKVQVMIAFINSVV
                     SMIFLGFMGFPQIWALGFMIFVLGLIPVAGVIVSLIPLTVIAFNTGGITKVFGVLLMI
                     CIVHAVETYILNPKLMSNRTKLPVCFVFIILLVGEHYLGVWGLLIGVPIFMFLMDILG
                     VKFTSR"
     gene            complement(11383..11691)
                     /locus_tag="KR294_001508"
     CDS             complement(11383..11691)
                     /locus_tag="KR294_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1540 domain-containing protein"
                     /protein_id="HBH0239590.1"
                     /translation="MKNNNLNCAATNCAYNTSGYCYAGSIKVDGMQATTTENTYCASF
                     EDKYTSGITSRSNETNQVDTDNIHCEAVKCKYNKNELCKAEKVHINERNASCETFEMK
                     "
     gene            complement(11751..12179)
                     /locus_tag="KR294_001509"
     CDS             complement(11751..12179)
                     /locus_tag="KR294_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239591.1"
                     /translation="MNNKLHELEKNLPEISCSFCTHLSFKGPSLDYRYDIRCVISDTK
                     PDFRGCCEYFEPEYTELNTGDLDNLYINFLETCLKVNYNDYINSMYWKLFKERTLLEN
                     NFKCSICGSTENVDVYHVNKNLGRETSKDVVVKCDKCNCK"
     gene            complement(12402..13859)
                     /locus_tag="KR294_001510"
     CDS             complement(12402..13859)
                     /locus_tag="KR294_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon starvation protein A"
                     /protein_id="HBH0239592.1"
                     /translation="MTTFLIGLAILLIGGALYGAYCEKVFGPDDRKTPALAQSDGVDY
                     VPMKKWKNSLIELLNIAGTGPILGPIQGILFGPIAFILIPIGCVFGGALHDYMSGMIS
                     IREKGAQMPSLISRFLGNKVFQVYNIFLCLLMLLVGAVFIYTPGDLVVTQILNMKSTI
                     NNPVVWIVYGLIFLYYLCATLFPIDKIIGKVYPIFGAILLLSAAGVGIGIFTQGYDLA
                     NLSLANWKGIHPDGIPLIPTFFVTVACGIVSGFHSTQATLIARSVSNEKEGKTTFYNM
                     MILEGLIAMIWAAAAMGIYNKGIPKELVGSPDVIGLVARDLLGSIGGIIAIIGVIVLP
                     ITSGDTALRSLRLMLADYFHYDQKEKKHRVILSICIFIPVIAILIFAKLSASGFNILW
                     RYFSWSNQTIAIFAFAMITVYLIIKEKNYIISLIPGMFYSFVIFSYIFNAQIGFNLNI
                     NISYVLAAIFTVLYAILTVRSGRKLKSKADTKLAD"
     gene            14277..15191
                     /gene="nadA"
                     /locus_tag="KR294_001511"
     CDS             14277..15191
                     /gene="nadA"
                     /locus_tag="KR294_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinolinate synthase NadA"
                     /protein_id="HBH0239593.1"
                     /translation="MDKDLTYQIKELKKEKNAIILAHFYQPPEIQELADAVGDSYYLS
                     EIARDCKEEVVVFCGVRFMGESAKILSPEKTVLMPVSNAGCAMADMVDEEGVIKLKQQ
                     YPNALVVCYINSTAKVKAHCDVSVTSSSAIKILENIDNKEIIFLPDKNLGGYIAEQFP
                     DKNFIFWDGYCKYHNNIRAEEIIELKDKYKNAEVLVHPECKKEIRDLGDYVGSTSGII
                     KYATNSKNKDFIIATEEGILHELKKNNPNKNFYIPGGKILCTDMKKTTLENLYSTLKN
                     MENEVIVEDEIMEKALNSLLNMHKLAEG"
     gene            15204..16505
                     /locus_tag="KR294_001512"
     CDS             15204..16505
                     /locus_tag="KR294_001512"
                     /EC_number="1.4.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-aspartate oxidase"
                     /protein_id="HBH0239594.1"
                     /translation="MNLEQDVLIVGSGVSGLYCALNLDKSLNVLVVSKSTIENNNTYL
                     AQGGISTARNIDDIESFVEDTMKAGQYKNRVEAVQVLADESIENVGQIVEYGMPLDKE
                     NGEIDYTREGAHSVNRIVHSKDNTGEVVFKTLLKEAKTRENITLIEDAYLLDILKDGN
                     KCIGARIFKSKKEIHVFSKIVVLATGGIGGLFKNSTNQRHLTGDGIAIALRNNIKIEN
                     LEYIQIHPTAFYEENNEGRRMLISESLRGEGAKLLNKNKERFVDELLPRDVVSKAIFE
                     QMEKDKLPYVYLDATHLDSEYLINRFSFIYNECLARGTDITKECIKVSPAQHYFMGGI
                     HVDLDSKTSMENLYAVGEISCTGVHGANRLASNSLLEGLVFSKRAAKNINSVIDNVKV
                     KFIDVPDMDIDIEQVKKENKILVIKEIERTSEDFGDELFDY"
     gene            16486..17322
                     /gene="nadC"
                     /locus_tag="KR294_001513"
     CDS             16486..17322
                     /gene="nadC"
                     /locus_tag="KR294_001513"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HBH0239595.1"
                     /translation="MNYLIIDRMIQDALIEDVPSEDITTNSIVDENSKSTVDLICKQD
                     GIIAGLGVFKRVFEILGDVDVKLYKNDGDRVKNREKIAVLTGSTRNLLVGERVALNYL
                     QRMSGIATITSRYVEKLEGTNTKLLDSRKTIPNLRILDKYSVKVGGGCNHRFNLSDGI
                     LLKDNHIGAAGSVKKAVELARKNTSFVRKIEVEVETLDMVKEAIEANADIIMLDNMSL
                     EMAKQAVDIINGRAIVEFSGNVNLDTIEDIGKIGVDVVSVGALTHSVKALDISMKNLR
                     NI"
     gene            17578..17910
                     /locus_tag="KR294_001514"
     CDS             17578..17910
                     /locus_tag="KR294_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE family protein"
                     /protein_id="HBH0239596.1"
                     /translation="MKVAYIFSSTNTHKILDKMIIPQLEQGTHGVDVLGMFFFMDNTL
                     FLSKGNPVGERLSKLHEKTDMIIMACDQCAIERGIENNLVDGATIGCFPNLYACLGSA
                     GVDQVITL"
     gene            18072..18257
                     /locus_tag="KR294_001515"
     CDS             18072..18257
                     /locus_tag="KR294_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239597.1"
                     /translation="MSEKYADKLEIKLYQAGKDFSYIKKYGIITKGTLIINQKKKYDR
                     LNKDTIERAIVEAINNN"
     gene            18284..19369
                     /locus_tag="KR294_001516"
     CDS             18284..19369
                     /locus_tag="KR294_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HBH0239598.1"
                     /translation="MNILEIVLNGVKDTIVASIVTLNGASGWLMISFILAGVLHNVLT
                     PRRFQKQLGNKKFSSLIKSTISGMFLPICSCGVIPLGISMYYSGAYLGPVLAFMTSTP
                     IINPIAVVLCLGLLGPKVTIIYLIAGFLVPFLVGFLGNCFGKEELSLHNDSEEEVIEL
                     EEEKRSFMENMIDGLKWSFGELALTISKYVVMGMVFAGFITTIFPNSIIQKYLGNPGL
                     LSLGSIAILACVMYVCAVGHIPFIAALVASGASPGIAITFLIAGAATNLPELISMFKL
                     IGKRTVIIYSVTLTLSSIIIGYITNLLLVNNNSVNLDATNSSIQLANKLMLNIPDSFE
                     YVCTILIILFAFKSIIPKMKEVIGNHA"
     gene            19362..19820
                     /locus_tag="KR294_001517"
     CDS             19362..19820
                     /locus_tag="KR294_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239599.1"
                     /translation="MLKKIVIISCIVVVLIILSKIVDDNIKEDASIPNVNKETLEYFR
                     KNYKEDIITCAEEDLNNDGKKDLVVIYKKSNNSNEMVVVVSDKNSHYITKPIPAPIEN
                     QTITFKNIDDKAPIEVIVSGSKNGNVGYAIYRVEGKKFVDLFGEDMDKCC"
     gene            19855..20946
                     /locus_tag="KR294_001518"
     CDS             19855..20946
                     /locus_tag="KR294_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBH0239600.1"
                     /translation="MKLSKKIQALILFGVMGTSILTGCSSKPKEKEEAKTGKDDYTIT
                     VGYYNCDHMTAGPVAESAGIYKDLGLNVKTVGNGKVPEAMAAGKMDAGYIGTKGLVGA
                     IPKGSPITIAANNHTGGSEYLIVSKDIKEPKDLIGKKIATDMSDFLWTSDYGPETGLP
                     TDPSKYEVVNMDSDKDKYLALKTGKIQAFTSCDPWGSVAENDGAGKIIASTQYKEKAN
                     GKEYNCCSFSLNKNFIKEHPDLAKKLVLAHTKAIEYIYTNPAEAAKIFAKYYNVEEEV
                     ALRTIYKKTVGEGRTLTWKVTGEEYKNNLQMYKDLKALDDIPKYEDTIDTSLLDSCGA
                     DDFDKFIKEKVNPEFPEGMSYEDWKAKVL"
     gene            20951..21175
                     /locus_tag="KR294_001519"
     CDS             20951..21175
                     /locus_tag="KR294_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239601.1"
                     /translation="MENMKNIIILFIIILGSIFIIFFNFEDKEEIKGKLRIGVSDDTS
                     GFVINYMVNRDYFENIKVSDIMDIFTINDC"
     gene            21185..21748
                     /locus_tag="KR294_001520"
     CDS             21185..21748
                     /locus_tag="KR294_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239602.1"
                     /translation="MQWALSSEEIDIAIICKDAAKQYVNVNSGFEIVGTVVQNSDIFL
                     LSDNNPEKIGVIQNRDYQSELVKKYYKNVEVAPLLGTALAYGLESNLVDGVVIDCIKS
                     IGLEGKRKSTTKLGDYDTYVLVVSKEFKKSKAYSDFITLYNKSVDALKNKATFKKALK
                     EYRNIRNIDMEEISNWKLKFLKIKAID"
     gene            21709..22338
                     /locus_tag="KR294_001521"
     CDS             21709..22338
                     /locus_tag="KR294_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0239603.1"
                     /translation="MEIKISKDKSDRLTKKKTDGSMDILYKIILLVIIFLVWHFAAKD
                     IGSSLLLPMPVDVIKGFFFCVTDAETVTNLFITLQRVLKGFMYALLFGLPIGFIMGFS
                     KTFERVLSPVVDSVRQVPIMAWVPLTIVWFGIGDGPTIFLIAFSGVFPIILNTIQGVR
                     AISKDYYNAARSMGASPIVIFTNVIVPASLPDILTGSRIAISTGWMSVI"
     gene            22515..23267
                     /locus_tag="KR294_001522"
     CDS             22515..23267
                     /locus_tag="KR294_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0239604.1"
                     /translation="MKLSVRDINKTFVNNRVHTKVLEDISMDIDDGQFVCLLGPSGCG
                     KTTLLTIIGGFQKSERGDVFINDKRVKKPGIDRAFIFQNYALFPWKTIRGNVLFPMKQ
                     QKIPKEKREEMLEELLVMSDLKGKEKLFPHQLSGGMKQRVAMIRALACNPEVLLMDEP
                     LGAVDFQMRQNLQEELERIWIKKKITALMVTHDVDEAVYMSDRVIVMSRDKGRIIDDI
                     NIDIPRPRIRGSQKYEEYKNKLTDTLSKCYEV"
     gene            23280..23765
                     /locus_tag="KR294_001523"
     CDS             23280..23765
                     /locus_tag="KR294_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239605.1"
                     /translation="MSQIEKYNSLDNTQQKIRISIMDMIIDKGSSVTLQEVTEYISKK
                     LNIEKEYIERTLQYFIYKNIMVVDGNSINFIYPVSALPTNHKVTLRDNRSFSAMCAID
                     AIGTSCTFNQDIKINSICSATGKEIEVIIKNEKIEYVNNPNLRVLHINLDKHLNWAAS
                     C"
     gene            23772..23921
                     /locus_tag="KR294_001524"
     CDS             23772..23921
                     /locus_tag="KR294_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239606.1"
                     /translation="MNFFWTKSDFDAWTNEAGLSNDEDIYCLDINEAIVESYKIFKLK
                     QKVLS"
     gene            complement(24058..24879)
                     /gene="yidA"
                     /locus_tag="KR294_001525"
     CDS             complement(24058..24879)
                     /gene="yidA"
                     /locus_tag="KR294_001525"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HBH0239607.1"
                     /translation="MYKLIALDIDGTILNTQKRITPEVFESIQEAKRAGAKVVITTGR
                     PLPGVKELLNQLNLTDEGDYVICFNGAIIQEVKSEKIIHDVEMSLDDFDFIYNNVCKK
                     YKTKIHINTMTNLITPNETPGKYTLHEAKLNNIEVKYIQKDKIDESIKICKIMIVDEP
                     ERLEEIIQQLPKNLFNKYTIVRSAPFYLEFLGKTTNKGTALKTLCTNLNIPIENAIAV
                     GDEENDQHMIKYAGLGVAMGNARNSIKEIADYVTDTNNENGVAKVINKYILNKAI"
     gene            25372..27066
                     /locus_tag="KR294_001526"
     CDS             25372..27066
                     /locus_tag="KR294_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HBH0239608.1"
                     /translation="MKFSEFKYERPNYNSMKKEFLSCVEDINNSRNYKEQQKNIHKIN
                     LLRNKIETLSNIASIRYSTDTFNKFYKEEKNYWDEYMPLYEELNSYFYNAIVNSKFKY
                     DLIKEFGEQFFTIVEYSLKSFSKEIISELQEENKLCSEYTRLLASAEIMFDGKIRNLS
                     GMGKFMYSKNRKTRELANKAYYNFFEENETKFDDIFDKLVKLRDKMSKKLGFEDFVEL
                     GYVRMMRSDYREYMIKNVRKQVLKYVVPMANELYEKQAKRIGLEYLSYIDEGVEFLTG
                     NASLKGDSRYIIKNGKRMYSELSKETNEFFDFMLENELMDLETKKGKGAGGYCTYIPD
                     YKSPFIFSNFNQTADDIDVLTHEAGHAFQLYMSRWIDMPEINFPTLDSCEIHSMSMEF
                     ITWPWMDLFFKEDTDKYKFTHLSSSIKFIPYGVIVDEFQHYIYKNPNVDKSKRKEIWR
                     FLEKKYLPHRKYGDNSFLERGCWWFKQGHIFKNPFYYIDYVLAQICALQFWKKMIQDR
                     DAGWKDYINICKVGGTKSFLDIVSMGNLYSPFDDGCIESIIGDVKSWFDEINDSKL"
     regulatory      27398..27508
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            27612..27983
                     /locus_tag="KR294_001527"
     CDS             27612..27983
                     /locus_tag="KR294_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrdX family protein"
                     /protein_id="HBH0239609.1"
                     /translation="MIIITNNPKVKEEVQGREVLFKDTTYIGILEASRDLIHEGYELL
                     SHPLYGSVKPNETPYRTVILKKGNRLDINSLTLIEEAIITASKFQNNKKTPKWTESVQ
                     DDFRVIDYDIFYNTIQRMQYE"
     gene            28080..29027
                     /gene="trxB"
                     /locus_tag="KR294_001528"
     CDS             28080..29027
                     /gene="trxB"
                     /locus_tag="KR294_001528"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HBH0239610.1"
                     /translation="MENVYDLVIIGSGPAGLAAGLYGARAKLKTLILEKDKTGGQIVI
                     THEIANYPGSVPNATGPSLIARMVEQCKEFGAEMLRDNIVDTELDGDIKVLKGEKAEY
                     RAKAVIIGTGATPRKIGCPGEKELTGKGVSYCATCDADFFEDFEVFVVGGGDSALEEA
                     MYLTKFARKVTIVHRRQGFRCAKSVEEKAKANPKIEFLLDTVIEEIKGDGILESVVFK
                     NKVTGETHEYFADEEDGTMGVFVFVGLDAQTDLFKGKVDMDEKGYIITDEDMRTNIPG
                     VFAAGDCRSKTLRQVVTATNDGAIASIVAEKYIDEKFGN"
     gene            29131..29448
                     /locus_tag="KR294_001529"
     CDS             29131..29448
                     /locus_tag="KR294_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol reductase thioredoxin"
                     /protein_id="HBH0239611.1"
                     /translation="MLDLDKATFEEEVLNAEGFVFVDFWSEGCEPCKALMPDVHKLAE
                     TYGDKIKFCKMDTTKARRLAIKQKVLGLPTMAIYKDGEKVDEVTKDDATVPNIENMIK
                     KYL"
     gene            29717..31003
                     /locus_tag="KR294_001530"
     CDS             29717..31003
                     /locus_tag="KR294_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006439082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase component B
                     subunit"
                     /protein_id="HBH0239612.1"
                     /translation="MRLELGKIFIKDIQFGDVTEVKDGVLFINKQEMLQEIGGDEHIK
                     SIDIELARPGESVRITPVKDVIEPRVKVEGNGGIFPGIMSKVDTVGEGKTHALKGVAV
                     VTTGKIVGFQEGIIDMTGEGAKYTPFSKLNNVVVIAEPIDGLKQYAHEKAVRMIGFKA
                     AMYLGEVARNLTPDEVSVYETKPLLESIKEYPELPKVGYVYMLQTQGLLHDTYVYGVD
                     AKQIVPTLLYPTELMDGAIVSGNCVSACDKNPSYVHINNGVVEDLYARHGKDINFVGV
                     IITNENVYLADKERSSNWTSKLCKYLGLDAVIVSQEGFGNPDTDLIMNCKKIEMQGVK
                     TVIVTDEYAGRDGGSQSLADADVRADAVVTGGNANQVVVLPKLDKVIGHLEVVDVIAG
                     GSDGSLRADGTIEVEIQAITGATNETGFGHLTAKGY"
     gene            31115..31588
                     /locus_tag="KR294_001531"
     CDS             31115..31588
                     /locus_tag="KR294_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:31247..31249,aa:Sec)
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase complex
                     selenoprotein A"
                     /protein_id="HBH0239613.1"
                     /translation="MSLLSNKKVLIIGDRDGIPGPAIEECVKTVEGAEVVFSSTECFV
                     UTAAGAMDLENQNRVKDAADKFGAENVVILLGAAEAEAAGLAAETVTAGDPTFAGPLA
                     GVALGLSVYHVVEEPIKSLFDESVYEDQISMMEMVLEVEEIEEEMSGIREEFCKF"
     gene            31620..32930
                     /gene="grdB"
                     /locus_tag="KR294_001532"
     CDS             31620..32930
                     /gene="grdB"
                     /locus_tag="KR294_001532"
                     /EC_number="1.21.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:32667..32669,aa:Sec)
                     /transl_table=11
                     /product="glycine reductase complex selenoprotein B"
                     /protein_id="HBH0239614.1"
                     /translation="MGKLKAVHYINQFFAGIGGEEKADTKPHVAETLPPISLQLDKLL
                     GEDIEIVGTVVCGDSYFNENIDSASEEVLSMVKGFEPQLFIAGPAFNAGRYGVAAGTI
                     TKVVKDALNIPALTGMYVENPGADMFKKDVYVVETSDSAAGMRKALPKIAKLAVKLAN
                     GEEIGTPKDEGYIARGIRVNYFHEDRGSKRAVDMLVKKIKGEPFETEYPMPNFDRVDP
                     SKAVKDLSKCKIALVTSGGIVPKGNPDRIESSSASKYGTYSIAGVMDLTEETYETAHG
                     GYDPVYANLDADRVLPVDVLRDLEKEGVIGKLHETFYTTVGNGTSVANSKKYASEIGA
                     ALVADGVDAVILTSTUGTCTRCGATMVKEIEKTGLPVVHMCTVVPISLTVGANRIVPT
                     IAIPHPLGNPALDPTEEKALRRGLVEKALNALTTEVDGQTVFEK"
     gene            33186..34718
                     /locus_tag="KR294_001533"
     CDS             33186..34718
                     /locus_tag="KR294_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014520415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III family protein"
                     /protein_id="HBH0239615.1"
                     /translation="MTYPVLKGAGYVLIHTPDMIVQNGSTCTVERATNPDSEFLKEVS
                     NHIRSYEDVVNYMPNQVYIGNRRPEELRDLPMPWCEQKIEGTRNGKFGEIMPQDEFIA
                     LMQISDAFDLVKLSQEFIDEVKPKIENNYPEIAPFVGKLKGDDIEEGKELVATHIAEG
                     LYHDGKFVGYVKRAHDVDVNLNAHTMFENLVVKASGVLSAIQMLRHSKIDPAEIDYVI
                     ECSEEACGDINQRGGGNFAKSIAEIAGLQNATGSDTRGFCAAPTHALIQAAALVKAGI
                     HKNVMVVAGGASAKLGMNAKDHVKKGLPVLEDVVGGFAVLVSENDGVNPVIRTDLTGK
                     HTVGTGSSPQAVMTALITSGLDRANLKITDVDVYSVEMQNPDITKPAGAGDVPEANYK
                     MIGALAVKRGDLEKKELKDFVSNKGLPGWAPTQGHIPSGAPYIGFLIDDLTTGNRNRA
                     MIVGKGSLFLGRMTNLFDGVSFIAERNTGVTEETSGISKDEIKKIIAESMKKLALDML
                     EE"
     gene            34729..35874
                     /locus_tag="KR294_001534"
     CDS             34729..35874
                     /locus_tag="KR294_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine reductase"
                     /protein_id="HBH0239616.1"
                     /translation="MSKKVIADVFLEVANAIESGEFGKKVKIGVTTLGSEHGVENMVN
                     GAQLAKSNLFDIVLIGPKVETDLEVVEVNDEKEMHAKMEELLDSGYIDACVTMHYNFP
                     IGVSTVGRVITPAKGKEMILATTTGTSATNRIEAMVRNAIYGIATAKSMGNKCPKVGI
                     LNVDGARQVEKCLKELKDNGYDMEFADSIRADGGCVMRGNDLLVGAPDVMVTDTLSGN
                     IFMKVFSSYTTGGDYEAQGFGYGPGVGEDYDRKVLIVSRASGSPVVANALKYAYDVVK
                     GDISNVARNEFAKVKKAKFDDIISSLTKKEVKAEKVEVKMPDKEIVTRQIAGVDIMDL
                     EDAVSELWKNGIYAESGMGCTGPIVLVNEAKGDLAVETLVKAGYTAK"
     gene            36184..37263
                     /locus_tag="KR294_001535"
     CDS             36184..37263
                     /locus_tag="KR294_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBH0239617.1"
                     /translation="MSRVKNVVELLETKGVDALYLTKKTNVNYISGFPDEEAYAVICK
                     DGNFLVTDSRYMELAEKVCKDFEIINWHNFDRSVAKAVKSVCDKVGIKKLGFERTNIV
                     FDKYEELKNLIEKDNGELIPTENIVETLRYVKDKDEIKNTRKACEIADKALEELIPHI
                     KAGVSEIELATRLEYFMKMNGAQNIGFETILISGAKTSLLHGKPSDKIIEKGDFVLID
                     YGAMYNGYISDTTRTFIVGGASEKQLEIYNLVKEAQNVGVENMKAGVHATIPDAEIRK
                     VVKKYEDYYYQGIGHGVGRDVHEEPFIGNYGDKIIEEGCIITMEPGIYFPGWGGVRIE
                     DTVLITKNGPERLTKFPKDLMILDK"
     gene            37376..37975
                     /locus_tag="KR294_001536"
     CDS             37376..37975
                     /locus_tag="KR294_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239618.1"
                     /translation="MYKKHKFIKNIKKAWYKIKLIDRCLIIVMAILMFQSIYNLFVNE
                     VNSQDTTTIDVVVRTTSAAIFGYFLSANFIKRPLRKYTNTDVSSNLFIDNNLSPKGQE
                     SNQNNIMNVKNTIGFTSEADNYEKKIPINNNEGFEEGETSELQIIIATVICIVALTVL
                     FVVRNFTTTTSASLGTISQMRDFVSGCVGFLLGCPSKPD"
BASE COUNT        14926 a         4080 c         7035 g        12085 t
ORIGIN      
        1 aaatatgagt ttatgtgtag aaataagtgc tttatatcag accaaaacgg atgtaatagc
       61 tttagtagaa gaagtgtctt tttttaaaac tttaaaaaat aaagctcttg taagtagggc
      121 aaattatata tttgggagag tttatctata tttatttaat aactttataa aaagtatgga
      181 atacttaatt gaatgtctaa aattggctca agaaaataat ttatactcta tagaggcttt
      241 ttgtaaatgt ataataagtt tgtgttattt agagagtgga aataatgtag aagctataaa
      301 atacataaat aatgtattag atgttgcaca cagtaataac tcaatatcag taactgaaag
      361 agtgtctata aaaatagacc ttatatgggc atatttaaaa gaagatatga ataaagaagc
      421 agaagttatt ttattaaaga ctataaaatt aatgaaagtt gttgaaggtg tatataagga
      481 ttatttatat tcatttatat ttttatattc agctgaaatt gagttaaaga aagataattg
      541 tagttttgaa aaggtaaaca cctatttaat tttatcaaaa aatatatata aaagttttgg
      601 agatgttttt atatataatt ctaaactaga ttacatatat aagttgtatg gagatttata
      661 tataaaattt ggtaatatag atgaaggtat aagttgttat ataaaaggtt taaatttagt
      721 taaaaagagt tcattgaatc ttagaaaaat atctatattt tatgggctaa tagcaaatgg
      781 atatgagcta aaaaaagatt ttaaactggc aatagaatat tataaaagta tggattggta
      841 ttctgatagg tgggaaaaaa ataattccta taaaacatct caagcaattc acaaacaata
      901 tgaactcaga caaaaacaag agagtttaag attactagtg gatgataata agaaattaga
      961 aaatgatatt ttaaaagatg gacttactaa actatataat agaagatatc tggaacagca
     1021 gttggattta tttaatgaaa ccagagacaa aaatatggtc gcaatactgg tcgatataga
     1081 ttgttttaaa agttataatg ataattatgg tcatctagca ggagataaag ttatagttaa
     1141 ggtaactgat attataagaa gtgtatttat agatattacc gaacacataa tcagatatgg
     1201 gggagaagaa attttaatat tagtagattc tatagaatca atcggtgttg aagagattga
     1261 taatatagaa ttatatatta aaagagtttt caaacttctt gaatttgagg gtattgaaca
     1321 tatatattct aaaataaaaa actatataac tataagtgct ggagtaagta taaaaagatg
     1381 tcgtagtaga aaagatgttg aaatattaat tgaagatgca gataagaacc tatataaatc
     1441 aaaaaaagca ggtagaaatc aatacattat aatttaaaat tgaggtgatt ttgttgcgaa
     1501 aaaaaatagg aattatagcc tctgatattg aattaaaaga aagaatagaa gaattatata
     1561 gagaagatgt agaaaatgga actataataa tcgacatact taacctagac ttaatggaaa
     1621 atcaaggtcg tatacttgtt gaaaaaggtg cccaagctat aattggtaga ggtggaggtt
     1681 atagtttagt aatagataca gtaaatgtac ctgttatacc aatgaatatg aagtcaactg
     1741 accttttaag agcaatagaa atagcaaaga aatattctaa aaaagtagta ttgattcttg
     1801 gagacaatga agtttctttt gactatgttg gctggagaaa tgtcataagt actgaaataa
     1861 ctgaagaatg gtttgaatct aagtatgaga taagaagtaa agttgtaaaa tatatagacc
     1921 aaaaagatga aattgtaatc gtaggaggag gtttggcatg ttcttttgca aggcaatatg
     1981 gaattgatag tgtatttgca actgctagtg atgaatctat aagagaagct gtagaatatt
     2041 gtaaaaaatt attagataca ttaggtgaag aaaagtttaa taatgaagtg ttacgaaata
     2101 tacttgatgg tataaaagat ggagtaattg ctatagatag taatggcagt ataattttgt
     2161 acaatgaaag tgcaaaaaac atgcttaaag tagagagaaa atgtgcactt aataaataca
     2221 tcttagatgt atttcctaaa atggagtgga tgttagattg tttacatgaa aaagaggacg
     2281 tagaagatag aaagataaga aatataaata atctaattgt taatactagg acaacattga
     2341 taaaagttga taatagtact tatggagttt taggaataat acaagatata accaagctac
     2401 aaaacttaga aagaaaaata agatttgact tgaatcaaaa aggtctctat gctagatata
     2461 cttttgatga ttttttattt aaagataaat taactaaaga atttattgaa gaagctaaaa
     2521 aaattggaaa aagtgattat acaactttac tttatgggga aagtgggtct ggtaaagaaa
     2581 ttatagctca tagtatacac aatataagta aaagaaaaga taggcctttt gttgctataa
     2641 attgtgctac tatagcagaa aatttacttg aaagtgaact ttttggctat gaagaaggtg
     2701 catttactgg tgctagaaag ggtggaaaaa gagggctatt tgaacttgct catggaggga
     2761 ctcttttttt agatgaaata aatagtctat cctttaatat tcagacaaaa ctattaagag
     2821 taatagagga acgtcaaata atgagaattg gttctgatta tataatacct ctggatataa
     2881 ggattatagc agcaacgaac gaatctttaa ccgaaaaaat agttatgggt acatttagag
     2941 cagacttatt ttatagattg agtagtttag agataaatat acctccttta agagacagaa
     3001 gagaagatat aatacctttg tttaacaatt ttgtaaatga agtattaaag gatgatggtc
     3061 tcaatggaat aaacagtata gatgaaaatt ttgttttgac taaagatgaa atggataagc
     3121 tatataatta tagctggcct ggaaatgtaa gagagttaaa gacaatagct caaaaatatg
     3181 ttgtgacagg taaaattaaa ttgagacaag atagagattt taaaactaaa aaattacttc
     3241 ctaactctga agtagacaaa tttaattctg aaacgacagc aagtgtagaa gtccaagatg
     3301 aatctataaa tataagtaag ataaatgatg gtaagataag tatagatata aaagaagtaa
     3361 ataagtatgt tgaagaaaaa ataataagta tgctttttgc tcaaggactt tctaaaaatg
     3421 aagttgcaca agttcttgga ataagcagga catctttatg gaagaaatac aataaaaata
     3481 tttaaatata attacatata aattattttg aagtaatgtt aattttttaa aacaagtgtt
     3541 aagaaaaatt aacattactt ttttgcaaat ttttattttt ttagacaggc atatatattt
     3601 ataagaaaaa tagttaaaac acttaattta ataatgaaaa aaataataat tctaaacaaa
     3661 atcaatttta cataaagtgg gatttattgg catagtaatt gcttaatata taatgtaaga
     3721 gtaaatacaa ttttaggggt gatggtatga gtcaaagtat ggttggtaag catgcaatgt
     3781 ggccaaaaga aaatgatgtt atatttagca tatctggcag agctcaagca gcagagaagg
     3841 cttttggtat ggataatgta ataaatgcaa caataggcgc tctaatggat gattcaggaa
     3901 aattgataac aatgaaaact gtatatgaag aatataaagc attagataac tgtgagatag
     3961 gtgcatatgc agctcttgaa ggtcaaccag attacttaga agcagttaaa aaagtatttt
     4021 tcagagatta cttaccagaa ggacatataa gagtattagc ttcaccagga ggaagtggtg
     4081 caataaaatt agctgtatgg aactatacta atgaaggaga tgaggtatta acatctgatt
     4141 ggttctggag tccatatgta agtatagctg aagaggctaa tagaaaagta gttaattacc
     4201 aactttttga tgaaaataga aggtttaatt ttgagtcgtt taaagaaaaa tttgtaaata
     4261 tagcagaaaa acaaggtaga gtctttacaa ttataaacac accagcgcat aatccaactg
     4321 gatatagtgt tgcagatgat gagtgggata aaatattaga cttatcaaaa gaagtcgcaa
     4381 aagataaaga caaaaagata atatttttcg tagattcagc atatattgac tttgcaggtg
     4441 atgatgatgt atgtagaaag ttttttaaga aattttctaa tttgcctgaa aacgttctcg
     4501 tattggttgg attcagtatg tcaaaaggat ttacagctta tggtatgaga atgggggcta
     4561 taatttgtat atcttcaagt gaagatgtag ctgaagagtt ccattactca tgtgttcatt
     4621 catgtagagc aaattggtca aattgtaata gaagtgccat ggcagtatta tctaacattg
     4681 taaatgaccc taaaaaattc aaagaatatg aggatgaaaa agaaatatac aaaaacatgc
     4741 ttactagaag agcagatgta tttgtaaaag aagctgaaag agtaggatta gaaattcttc
     4801 catatatagc aggtttcttt gtaagtatac catgtgataa tccaaaagaa gtatgtgaag
     4861 aattgactaa acataattta tttgcagttc cattaaaaat gggtttaaga tttgcagttt
     4921 gtgcagtttc tgaagataaa tgtaagaaag caccaagtat tataaaagaa gcacttgaaa
     4981 gtttagaagt aaaaataaat aattaatttc attgaacaaa ttgggtggac tatgaattta
     5041 ataattgtag atggagggaa ttttatatga aacaattgat gacaggtaat gaagcaattg
     5101 cacgtggagc ctatgaggct ggtgttaaat atgcatctgc atatccaggg actccaagta
     5161 cagaaatatt agaaaatata gcaacatata aagatgcaat agttgcagag tgggctccaa
     5221 acgaaaaggt agcacttgag gctgctatag ggggttcaat tgcaggagca agaacaatgg
     5281 cttctatgaa acatgttggt ttgaatgttg cagctgatcc aatatttact tatgcatata
     5341 caggggtaaa tggtggtatg gtacttatta cagcagatga gccgggaatg cattcatctc
     5401 aaaatgagca agacaatagg atgtatgcaa aatttgcaaa gataccttta tttgagccat
     5461 caactagtca agaagctaaa gatatgataa aagaagcttt tgaagttagt gaaaaatacg
     5521 atacaccagt tttatataga gttacaacaa gactttgtca ttcaaaagga ttagtggagt
     5581 gctatgatag agaagaagtt gaaattaaag agtatgttaa aaatgctaag aaaatggtaa
     5641 ctgttccagc aaatgctcaa ataagaaggg gcgttgttga agaaagaatg gaaattctta
     5701 aaaaattctc aaatgaaact gatttaaact actatgaaat aaatgataca aaaataggtg
     5761 ttatagcctc tggtatgtgc tgtaattttg ccaaagaagt ttttggaaaa aatgcatcat
     5821 atatgaaact aggatttaca aatccattac cttatgaaaa aataaaagaa tttgcagaaa
     5881 aagttgataa aatatatgtt atagaagaaa atgacccatt tatagaagaa caaataaaag
     5941 catatggaat agattgtatt ggaaaagatg taataccacc atatggagaa atgacaccag
     6001 atgttttaag aaaagctata tttggaaaaa caaatgatac tatagaatac aaatctgaat
     6061 tagtaacacc aagaccacca agtttctgtg caggatgtcc acatagagga ttcttctatg
     6121 aacttggaaa gagaaaaaat ttaatagttg gtggagatat aggttgttat actcttggat
     6181 ttgctcctcc atataatgga atagattatg ttgtttgtat gggttctgct tttggaactg
     6241 cacatggagc tcaaaaagtt cttaatatga aggatgataa tgaaaaaaga ttggtaggtg
     6301 tacttggaga ctcaacattc ttccatacag gaataaatgg acttttagat gttgtttaca
     6361 atagaggtaa ttctatttcg gttatattag ataatagaat aactggaatg acaggtcacc
     6421 aagaaaaccc aggttcagga tatactttac aaggtgctaa aactaaagaa gttgatatag
     6481 aaggattagt taaagcttgt ggaatagaac atgtaagagt tataaaccct aataatttaa
     6541 aagaagtaaa tgaagcacta gattgggctt tagctataga agatgaacca tcagtaataa
     6601 taacaagatg gccatgtgta cttaaaaaat tctctaaaga agatatagaa gaatttaata
     6661 atccatttaa gactaagtgt aaagttgacc atgataaatg tataggatgt aaattatgtt
     6721 tgaaaactgg atgtccagct ctatcatttg ataaagagaa taagttatca aatatagata
     6781 gaaatcagtg tgtaggatgt ggagtatgtg cacaagtttg tccaaaacaa gcaatagtta
     6841 aggaggaaaa ataatatgac taagagtata cttttggtag gtgtaggagg tcaaggaact
     6901 atacttgcta gtaaattatt aactatggga ttgatggaag ctggatatga tgtaaagatg
     6961 agtgaaatac atggaatgag tcaaagagga ggttcagttt cctcacaagt tagatatgga
     7021 gattgtgttc attctccagt tatagaaatt ggtggagcag atatattagt atcttttgaa
     7081 aaaatggaag ctttaagatg gttcaattat ttaaaaccag aaggaaaagc tttagtaaat
     7141 aatcatagga tagattctat gactgtttta atcggaggag ctgaatatca agaaagtgat
     7201 atagatgcag agttaagtag attaaatgca aaagttataa atgcagctga taaagctgaa
     7261 gaactaggaa attcaaaaat aatgaatgtt attttattag gatgtctagt taaatctatg
     7321 caattagagt ctattgattg ggaaaaaatt ataagtgaaa atgttaaacc aaaatttgtt
     7381 gaattaaaca taaaagcttt ccatgaaggt atggaaatgg ttagcaaata gtttataata
     7441 gatataaata gactatagaa attaaggtga aaggaagaaa attatgactt acagaatatt
     7501 agccataaat ccaggttcta cttctacaaa aatagcagta tatgatggag aagaacaaat
     7561 tcttgtgaag acgatagacc atccagctga agagattgca aaatataata ctatacaaga
     7621 ccagtttgaa atgcgtaagg aagcagtttt gaatattctt aaagaaaata gtatagactt
     7681 aaaatctctt agtgcaatag taggaagagg tggagtttta ccaccagtaa aatcaggagc
     7741 atatttagta aatgaagaaa tgattgatgt actaagacat agaccagtac ttgaacacgc
     7801 ttccaattta ggtgctgttg tggcacatgc aatatcagaa cctcttggaa tcaactcata
     7861 tatttatgat tctgttgcag tagatgagct tatagatgta gcgagaatat ctggactttg
     7921 tggaatggat agatcaagtg cagggcatgc attaaatact agagcaatgg ctttaaaata
     7981 tgctaaggat aaaggaaaag attataagag cttaaactta atagtagctc acattggtgg
     8041 aggagtaagt atttatcttc atgaaaaagg aagaatggtt gatatgctat ctgatgatga
     8101 aggaccattt tctccagaaa ggtcaggaag agtacctgct acaaaattag tggctgcctg
     8161 ttattcaggt caatattcag aaagagaaat gactaaaaag ataagaggta aaggtggtat
     8221 agtttcatac ctaaatactg tagatgctag agaagttgaa aaaatgatag cagaaggaaa
     8281 tgaagaagca aaaattattt atgaagcaat ggcttatcag ttagcaaaag gtattggaga
     8341 gttagcaact gtagtagatg gaaaggtaga tgctataatt ataacaggtg gaattgcata
     8401 ttctgaaatg tttacttcaa tggttaaaaa gaaagttgag tttatagcac cagtagaaat
     8461 tatggcagga gaaaatgagt tggaatcact tgcttttgga actttaagag tactaaatgg
     8521 agaagaagaa gctagaattt atagtgaaaa ttaataagaa aaactaaaaa tgtttatata
     8581 ctaaaaaagt ggtatatccg ttttttatac acgaaagctt agagtatagg tgaaaatgta
     8641 taaaatttgg attgccactt tttataatta aaattttatc ttaacctaat aaataattct
     8701 gtaaaatttc gtatttatat atatatttta ttggtattta ttgttattat tattatgagg
     8761 agtgattttt gatgggaaaa ataagtttaa aaagtatgat aagattattt tcaggttttt
     8821 ttatatttgc aatttcttct gtgcttatga ttaatgcaca tgtaggtctt atgccttggg
     8881 atgtacttca ccaaggttta tctataaagc taggcataac tataggtcag gcttctataa
     8941 tggtaggagt tgtaattgtt atattggatg cagtttttgg tgaaaatata ggatggggta
     9001 ctttactcaa catgacattt ataggaattt ttattgattt agtaatattt tctggagtga
     9061 tacctcatgc aagcaacact tatataggtg tgtttatggt tgttatagga attattttgg
     9121 cagctatagc aagttttcta tacttaggtg tttgtttagg aagtggaccg agagatgggc
     9181 ttatgattgc tcttcagaaa aaaactaata aatctgtacg tcttgttaga acaattcttg
     9241 aaatactagc attagttgtt ggatggttat taggaggttc tgtaggtatt ggtacgcttg
     9301 taagtgcttt aggtttagga tatgtattac aaatagtgtt tagaatattt aaatttgaca
     9361 caaaattgct gaaacataga tttattatag atgatataag agaatggaag gaaaagaaaa
     9421 gcaatgaaca taaatgtaaa tcaagtattg taataaaaaa tgagcagaat taattatgct
     9481 aaaatatatt tgtagtttat ctaatttata gtaaagtcaa ggagattttg aaatggaatt
     9541 atgggattta tataatgctg atggaattaa aacaggaaat gttataaaaa gaggtaattc
     9601 tattgaagaa ggttattacc atttggcagt tgaagtgtgg attttaaata gtaactctca
     9661 aattttaatt cagaaaaggt ctaaaagtaa aaaaacattg ccaaatatgt ggggaatgac
     9721 aactggatgt attgtttctg gggaagacag tttagaagga gcaattcgcg aagcaaagga
     9781 agaaataggg atagatataa ctaaagatga gatgaaagtt tttagaagta tgattcatga
     9841 agatactctt tgggatgtat acttagttaa aaaagaatat gatatatcta aagctatttt
     9901 acaggaggaa gaagtaagtg atataaagtg ggtaagcaca gatgaaataa gacaattact
     9961 aaaagagggt ttgttttttg aatatccaga gatatacgaa ttgctatatg agatagataa
    10021 taataaatta aatatatgat gtagagcaga tttcagtata agtaagatta tttaaaatgt
    10081 atcttctcta aattttaata ttgttttatg aaaattaata agttattttt agtatttttc
    10141 tacttgtttt ttgagattaa aataaaaagg gcagtcatta taaagtcata aaaatttggg
    10201 gaggatttaa actatggaag ataacaaagg attggcacgt gacagttcaa aatataaaat
    10261 tgtttctata tctgtcgtag taattattct aattacattt tggtatatgt taaatatggt
    10321 gcttttaaca tttattatga cttttatttt ctataacttg cttgtagcca caagaaaacg
    10381 aattaagaag ttttcttctt taaatattcc agattcattg ataattatag tgttatatgc
    10441 actatttgct atattgttag tattgattag ctatgcagtt gtaccaataa ttatagttca
    10501 acttacagag ttgagtaggg tttttagtga ttttgatgta aatcaatttg ctcaatcttt
    10561 aggaccgaaa ttgtatccta ttgtctcaaa gctggatttt aataaatata tttcacaagc
    10621 agggctactt atagcatcaa cagcaacaaa agttggaagt tttggagtaa atatattatt
    10681 ggcattttta ctgagtttac tccttttact tgaaaaaaat gaaattaaaa attttggaga
    10741 taaactttct gatagtaaga tttcttttat ttataattcg cttgtatttt ttggaaagag
    10801 ctttgttaaa aattttggtg aagtaatgaa agtacaagtt atgattgcct ttataaattc
    10861 tgttgtttct atgattttct taggtttcat gggattccct caaatatggg ctttaggatt
    10921 tatgattttt gtgttgggtc ttattccagt agcaggagtt atagtgtctt tgattccatt
    10981 aactgtaata gcatttaata caggaggaat aacaaaggtt tttggagttt tacttatgat
    11041 ttgtatagtg catgcagtag aaacatacat attaaaccct aagttgatgt cgaatagaac
    11101 taaacttcca gtttgttttg tttttattat tttacttgta ggagagcatt atttaggtgt
    11161 atggggatta ctaattggag ttccaatatt tatgttcctt atggatattc tgggtgttaa
    11221 atttacttct aggtaatata ttaaaataat aatttatttt tatatataaa ttatgaattg
    11281 ttttaaaaaa gaacctataa atagacatca ttaataaaga catctatttg ataggttcaa
    11341 ttttgctttg tataaatact ataaaactaa ataaaaagaa atttatttca tttcaaaagt
    11401 ttcacaactt gcatttcttt catttatatg aactttttca gctttgcaaa gttcattttt
    11461 attgtattta cattttacag cttcacaatg aatgttatct gtatcaactt ggttagtttc
    11521 attagaacga ctagttatac cagatgtata tttgtcttca aaagaagcac aataagtatt
    11581 ttctgtagta gttgcttgca ttccatctac ttttatacta ccagcataac aatatccact
    11641 agtattataa gcacaattag tagcagcaca atttaaatta ttatttttca taaataacct
    11701 cctaagtttt atttaaactt attatgtgaa gttatctaaa ttttatacac ttatttacaa
    11761 ttacatttat cacatttaac aactacatct ttggaagttt cccttcctaa atttttatta
    11821 acatgataca catcaacatt ttcagttgat ccacatatag aacatttaaa attgttttct
    11881 agtagggttc tttctttaaa taacttccaa tacatagaat tgatgtaatc attataattt
    11941 accttgaggc atgtctcaag aaagtttatg tatagattgt ctaaatctcc tgtatttaat
    12001 tctgtatatt ctggttcaaa atattcacaa catcctctaa aatcgggctt tgtatctgaa
    12061 ataacacatc taatatcata tctatagtct aggctaggcc ccttaaatga aagatgtgtg
    12121 caaaaagaac aagatatttc tggtagattt ttttcaagtt catgtaattt attattcata
    12181 agtattcctc caaaaaattt attttaagta tataaatgaa tagattattt taaaactttt
    12241 atttatttat attagagatt taggataaat attccaataa ggagtaaata cttaagtatt
    12301 tattactgta ttaaataaaa aagaggcaaa tctaacttga gattgcctac ttttttatca
    12361 ttttttaata aaatttattc taagtattat tttatttaga tttagtcagc caacttagta
    12421 tctgctttgc tttttaactt tctaccagag cgtacagtta aaatagcata taatacagta
    12481 aatatggcag ctaaaacata tgatatattt atgtttaagt taaatccaat ttgagcatta
    12541 aatatataac tgaatataac aaaggaataa aacataccag gaattaagct tataatataa
    12601 ttcttttctt ttattataag gtaaactgta atcattgcaa atgcaaatat ggcaatagtt
    12661 tgattactcc aagagaagta tctccacaat atattaaatc cagaagcact aagctttgca
    12721 aatataagga tggctatgac aggaataaat atacagattg acaatataac acgatgtttc
    12781 ttttcctttt ggtcataatg aaagtaatct gcaagcatta atcttaaaga tcttaaagct
    12841 gtatctccag aagttattgg taaaacaatt acacctatta tagctatgat accaccaata
    12901 gaaccaagta aatctcttgc aaccaaacct attacatcag gagaacctac taattcttta
    12961 ggtattcctt tattgtaaat acccatagca gctgcagccc aaatcattgc aattaaacct
    13021 tctaaaatca tcatattata aaaagtagtt tttccttctt tttcatttga aactgatctt
    13081 gctataagag tagcttgagt tgagtggaat ccagaaacaa taccacaagc aactgtaaca
    13141 aagaatgtag gaataagagg aataccatca ggatgaatac ctttccaatt tgcaagactt
    13201 aaattagcta aatcataacc ttgtgtaaag attccaattc caacaccagc agcagataaa
    13261 agtagaatag ctccaaatat tggatatacc tttcctatga ttttatcaat tggaaatagt
    13321 gttgcacaca agtaatatag aaagataagt ccataaacta tccagacaac tggattattt
    13381 atagtcgatt tcatatttaa aatttgagta acaactaaat ccccaggtgt ataaataaaa
    13441 actgcaccaa ctaaaagcat taaaagacaa aggaatatat tatagacttg aaatacttta
    13501 ttacctaaaa atctactgat aagagaaggc atttgtgctc ctttttctct tatactaatc
    13561 attccactca tatagtcatg caaagctcct ccaaatacac agccgatagg tattagtatg
    13621 aatgctattg gaccaaacaa tataccttgg ataggtccta gaattggtcc tgtaccagct
    13681 atattaagca actcaattag actatttttc cattttttca ttgggacata gtctactcca
    13741 tcactttgag caagtgcagg tgtttttctg tcatctgggc caaatacttt ttcacaataa
    13801 gcaccatata aagcacctcc tattagtaat atagccaagc cgattaagaa tgttgtcata
    13861 atatcacccc atttataaaa ttttttggtc tttgtataca tattatctaa atgtgtagat
    13921 ttatattgaa tttaattctg gacaacctac aaattctata aagtattaca actaatataa
    13981 tttcagaaat aaatacatat acataaccat gtacttagta tacaggtatt tggtaatatt
    14041 ttcaatgtta tagcaataaa gaatataaac aaaattctga taatatttta caaaaaaatt
    14101 aaaaaatata aaaattagtt taaatagatg gagaaaaaag gaaaatcaat tgagaatata
    14161 aatgtctata tcttaacaat attaagaggt ttaaaattct tgaagaaaga atagtcaagt
    14221 gatataatgg gtttacaggt gtatatacac tagtacatat agaaagcggt gcaattatgg
    14281 ataaagattt aacatatcaa atcaaagagc taaagaaaga aaaaaatgca ataatacttg
    14341 cccattttta tcaaccacca gaaatacaag aattagcaga tgcagttggt gactcatatt
    14401 atttaagtga gattgctaga gattgtaaag aagaagtggt tgtattttgt ggagtaaggt
    14461 ttatgggaga aagtgctaag atattatcac ctgaaaaaac tgtattgatg ccagtaagta
    14521 acgctgggtg tgctatggca gatatggtag atgaagaagg cgtgataaaa ttaaagcaac
    14581 agtatccaaa tgctttggtt gtatgttata taaactctac agctaaagtt aaggcacatt
    14641 gtgatgtttc tgttacatct tctagtgcaa ttaaaatact agaaaacata gataataaag
    14701 aaattatatt ccttccagat aaaaatttag gaggatatat tgcagaacaa tttccagata
    14761 aaaactttat attttgggac ggatattgta aataccataa caatataaga gctgaagaaa
    14821 taattgagtt aaaagataag tataaaaatg cagaagtatt agtacatcca gaatgtaaaa
    14881 aagaaataag agatttagga gattatgtag gtagtacatc aggaataata aaatatgcta
    14941 ctaatagtaa aaacaaagac tttataatag caactgaaga aggtatatta catgaattaa
    15001 agaaaaataa tcctaataaa aacttttata ttcctggtgg aaaaatacta tgtacagata
    15061 tgaaaaagac aacattagaa aatttatata gtacacttaa aaatatggaa aatgaagtta
    15121 ttgtagaaga tgaaatcatg gaaaaggctt taaattcact gcttaacatg cacaaattag
    15181 cagaaggata gagggataga cttatgaatt tagaacaaga tgttttaata gttggaagtg
    15241 gagtttcagg attatactgt gcattaaatt tagataaaag tttaaatgtg ctagtagtat
    15301 cgaaatcaac aattgaaaac aacaatacat atcttgcaca aggtggaatt tcaactgcta
    15361 gaaatattga tgatatagaa tcctttgtag aagatacaat gaaggctggg cagtataaaa
    15421 atagagttga agcagttcaa gtacttgcag atgaatctat agaaaatgta ggtcagatag
    15481 tagaatatgg tatgccttta gacaaagaaa atggagagat agattacaca agagaaggag
    15541 cacatagtgt aaatcgaata gttcatagta aggataatac tggagaagtt gtttttaaaa
    15601 ctttattaaa agaagctaaa actagagaaa atataactct tatagaagat gcatatcttt
    15661 tagatatatt aaaagatggc aataaatgta taggagctag aatttttaaa tctaaaaaag
    15721 agattcatgt tttttcaaaa atagtagttt tagctacagg tggaattggt gggcttttta
    15781 aaaattctac taatcaaaga catcttacag gtgatggaat tgcaatagct ttaagaaata
    15841 atataaaaat agaaaattta gaatatattc aaatacatcc tacagccttt tatgaagaaa
    15901 ataatgaagg taggagaatg cttatatctg aatcattaag aggagaggga gctaaacttt
    15961 taaataaaaa taaagaaaga tttgtggatg aacttcttcc tagagatgta gtttcaaaag
    16021 ctatttttga gcaaatggaa aaagataaat taccttatgt gtatttagat gcaacacatt
    16081 tagatagtga atatttaatt aatagatttt cttttattta taatgaatgt ttagctagag
    16141 gaacagacat aacgaaagaa tgtataaagg tatctcctgc acaacattat tttatgggcg
    16201 ggatacatgt agatttggat tcaaaaacat ctatggaaaa tttatatgca gttggtgaaa
    16261 ttagttgtac aggtgttcat ggagccaata gattggcaag taattcatta cttgaagggc
    16321 ttgtattttc aaaaagagca gctaaaaata taaactcagt tatagataat gtaaaagtta
    16381 agtttataga tgtaccagat atggatatag atatagaaca ggtaaaaaaa gaaaataaaa
    16441 tattagtcat aaaagaaatt gaaagaacaa gtgaggattt tggcgatgaa ttatttgatt
    16501 attgatagaa tgatacagga tgctttgata gaagatgttc caagtgaaga tataacaact
    16561 aattctattg tggatgaaaa ttctaaatct actgtagatt taatttgcaa acaagatggt
    16621 ataatagctg gcttaggtgt atttaagaga gtttttgaga tacttggtga tgtagatgta
    16681 aaattatata aaaatgatgg tgatagagta aagaatcgtg aaaagatagc tgtattaaca
    16741 ggtagtacta gaaacttact tgtaggagag cgtgtagcat tgaattattt acagagaatg
    16801 agtggtatag ctactattac aagtaggtat gttgaaaagc ttgaaggtac aaatacaaaa
    16861 ttattagata gtagaaaaac gatacctaat cttagaatat tagataagta ttctgtcaaa
    16921 gtaggtggag gatgcaatca tagatttaat ttatctgatg gaatattgct taaagacaac
    16981 catattgggg ctgctggtag tgttaagaag gcagttgaat tagctagaaa aaatacttct
    17041 tttgttagaa agatagaagt ggaagtggaa actttagaca tggtaaaaga agcaatagaa
    17101 gccaatgcag atataataat gttggataat atgagtttgg aaatggcaaa acaagcagta
    17161 gatattataa atggaagagc cattgtagaa ttttccggaa atgtaaattt agatactata
    17221 gaagatatag gaaaaattgg tgtggatgtt gtttctgtag gagcgcttac acattctgtt
    17281 aaagctctcg atataagtat gaagaatttg agaaatatat aaattttata ttgaaataaa
    17341 cttaattaaa atagactcct taaatttgtt ttataaattt aaggagtcta ttttttattc
    17401 attaaaatta ataaaaatag aaaaaaatca atcaataatt taataaaaat agataaatac
    17461 tatatacact tttaataata tagttaatat ctattttaca gataaataag aataaactta
    17521 taatataatt gtatctgtaa aattttgtaa aatataaaaa gtataggggg aataaaaatg
    17581 aaagtagctt atatttttag tagtactaat acacataaaa ttctagacaa aatgataata
    17641 ccacaacttg aacaaggaac tcatggagta gacgttctag ggatgttttt ctttatggat
    17701 aataccttat ttttatctaa aggtaatcct gtaggcgaga gactaagtaa attacatgaa
    17761 aaaactgata tgataataat ggcttgtgac caatgtgcta tagaaagagg tatagagaat
    17821 aatttggttg atggagctac aattggatgt ttcccaaacc tatatgcttg tttaggcagt
    17881 gcaggtgtgg accaagttat aacgttataa attagtatag gatacaatcc atagaaaaat
    17941 ttattttctg tggattattt taagtaaaag ataaattgtt taaagtaggg gatgaacaaa
    18001 tgtctaaaat tttagttgaa tttataaaca cttgaccatc ttgtgatgaa catggagtgt
    18061 ttataaaaaa aatgtcagaa aagtatgctg ataaattgga aataaaatta tatcaagcag
    18121 ggaaagattt ttcgtatata aaaaaatatg ggattataac aaaaggaact ttaataataa
    18181 atcagaaaaa gaaatatgat agattaaata aagatacaat tgaaagggca atagtagaag
    18241 ctataaacaa taattaaaag tttaaaaatt aggagtatca aaaatgaata tattagaaat
    18301 tgttttaaat ggagttaaag atactatagt agcttctata gttacactga atggagcatc
    18361 aggatggctt atgataagtt ttatcttggc aggtgtactt cacaatgttt taactccaag
    18421 aaggtttcaa aaacaacttg gaaataagaa attttcttct ttaattaaaa gtactatctc
    18481 aggaatgttt ttaccaatat gtagttgtgg agtaatacca cttggaataa gtatgtatta
    18541 ttcaggagca tatttaggac cagtacttgc ttttatgaca tcaactccaa taataaatcc
    18601 aatagctgta gttctttgtc taggtctttt aggtcctaaa gttacaatca tttatctaat
    18661 agctggtttt ttagtaccat ttttagtagg atttttagga aattgttttg gaaaagaaga
    18721 attatcactt cataatgatt cagaggaaga agtaatagaa ttagaagaag aaaaaagaag
    18781 ttttatggaa aatatgattg atggtcttaa atggtctttt ggtgaattag cccttactat
    18841 tagtaaatat gtagtaatgg gtatggtttt tgcaggattt ataacaacta tttttccaaa
    18901 tagtataatt caaaaatatt taggaaatcc aggtttgcta tctcttggaa gtatagcaat
    18961 acttgcatgt gttatgtatg tatgtgctgt aggacatata ccgtttatag cagcccttgt
    19021 tgcaagtgga gcatctcctg gtatagcgat aacatttcta atagctggag cagctacaaa
    19081 tctaccagaa cttataagta tgtttaaact tattggaaaa agaactgtta ttatatattc
    19141 tgtaactttg acactgtctt caataataat tggatatata acaaatttac ttttagtgaa
    19201 taataactca gtaaatttag atgcaacaaa ttcttcaata cagttggcaa ataaactaat
    19261 gttaaatata cctgatagtt ttgagtatgt atgtactatt ttaattattt tatttgcatt
    19321 taaatcaata ataccaaaga tgaaagaggt cataggaaat catgcttaaa aagatagtta
    19381 taatatcctg catagtagtt gtgttaatca ttttatcaaa aatagttgat gataacatca
    19441 aagaagatgc ttctattcca aatgtgaata aagaaacatt agaatatttt agaaaaaatt
    19501 ataaagaaga cataataact tgtgctgaag aagacttaaa taatgatggg aaaaaagatt
    19561 tagtagttat atataaaaaa agcaataatt caaatgaaat ggtagtcgta gtttctgata
    19621 aaaatagcca ctatataaca aagccaatac cagcacctat agagaatcaa actataacct
    19681 ttaaaaatat tgatgataaa gcaccaatag aagtaattgt atcagggtct aaaaatggta
    19741 atgtaggata tgctatttac agagtagagg gtaaaaaatt tgttgattta tttggcgaag
    19801 atatggacaa atgttgctaa aaataaaaat aatacataaa ggtgggaaat ttatatgaaa
    19861 ttatctaaga agattcaagc attaatctta tttggtgtaa tgggtacatc tatattaaca
    19921 ggatgtagta gtaaaccaaa agaaaaagaa gaagcaaaaa ctggaaaaga tgattataca
    19981 ataacagtag gttattataa ttgtgaccat atgactgcgg gaccagtagc agaatcggca
    20041 ggaatatata aagatttagg tcttaatgta aaaactgttg gaaatggtaa agttcctgaa
    20101 gctatggcag caggaaaaat ggatgcaggt tacataggaa ctaaggggtt agttggagca
    20161 atacctaagg gttcaccaat aacaatagca gctaacaacc atactggtgg ttctgaatat
    20221 ttaatagttt caaaagatat aaaagaacct aaagatttaa taggtaaaaa aattgcaaca
    20281 gatatgagtg atttcttatg gacaagtgat tatggtccag aaacaggtct accaactgac
    20341 ccatcaaaat atgaagttgt aaatatggat tcagacaaag ataaatattt agctcttaaa
    20401 actgggaaaa ttcaagcttt tacatcttgt gacccttggg gttctgtagc tgaaaatgac
    20461 ggtgcaggaa aaataatagc atctactcaa tataaagaaa aagctaatgg caaagaatat
    20521 aactgttgtt cattctcatt aaacaaaaac tttataaaag aacatccaga tttagcaaaa
    20581 aaattggttc tagcacatac aaaagcaata gaatatatat atacaaatcc agctgaagca
    20641 gctaaaatat ttgcaaaata ttataatgta gaagaagaag ttgcacttag aactatctat
    20701 aagaagactg ttggagaagg tagaactctt acttggaaag ttacaggtga agaatataaa
    20761 aataatttac aaatgtataa agatttaaag gctttagatg atatacctaa atatgaagat
    20821 acgattgata caagcttatt ggactcttgt ggagctgatg attttgacaa atttataaaa
    20881 gaaaaagtta acccagagtt tcctgaaggt atgagttatg aagactggaa agcaaaggta
    20941 ttataaataa atggagaata tgaaaaatat aataatactt tttatcatta ttttgggaag
    21001 tatatttata atatttttta attttgaaga taaagaagaa ataaaaggaa aattaagaat
    21061 aggggtatct gatgatacct ctggttttgt aataaattat atggtaaata gagactactt
    21121 tgaaaatata aaagtaagtg atataatgga tatttttaca attaatgatt gctgagcaag
    21181 tacaatgcag tgggctctga gttcagagga aatagatata gcaatcatat gtaaagatgc
    21241 tgcaaaacaa tatgtaaatg taaatagtgg atttgaaatt gttggtactg tagttcaaaa
    21301 ttctgatata tttctattaa gtgataataa tcctgaaaag ataggagtca ttcaaaatag
    21361 agattaccag tcagaattgg ttaaaaaata ctacaagaat gtggaagtag ctcccttatt
    21421 agggactgca ctagcatatg gattagaaag taatttagta gatggtgttg taatagattg
    21481 cataaagtca attgggttag agggcaaaag aaaatctaca actaaattag gagattatga
    21541 tacctatgta ttagttgtaa gtaaagagtt taaaaaaagt aaagcatata gtgattttat
    21601 aacactttac aataaaagtg ttgatgcttt aaagaataaa gctacattta agaaagcatt
    21661 aaaagagtac aggaatataa gaaatataga tatggaggaa ataagcaatt ggaaattaaa
    21721 atttctaaag ataaaagcga tagattaact aagaaaaaaa ctgatggtag tatggatatt
    21781 ttatataaaa taatactatt agttattata tttttagtct ggcattttgc agcaaaagat
    21841 atagggagtt ctttgttact tccaatgcca gtagatgtaa taaaaggttt ctttttctgt
    21901 gtgacagatg cagagacagt cactaatctt tttataacat tgcagagagt acttaaaggt
    21961 tttatgtatg cattattgtt tgggcttcca ataggattta ttatgggatt ttctaaaact
    22021 tttgaaaggg ttttatctcc agtagtagat tctgtaaggc aagttccaat aatggcatgg
    22081 gttcctctta ctatagtatg gtttggtata ggagatggtc caacaatatt tttaatagct
    22141 ttttcagggg ttttccctat aattttaaat actattcaag gagtaagagc aatatcaaag
    22201 gattattata atgcagctag aagtatggga gcatcgccaa ttgtgatatt tacaaatgta
    22261 attgttcccg catctcttcc agatatacta actggttcaa ggattgctat aagtacagga
    22321 tggatgtctg ttatctgagc cgagtttata gctacgagtg ccggtctcgg ttactcaatg
    22381 gtacaagctc aaacattaat gcatacagat gtattaattg ggcttatgat atttgcagct
    22441 ttaataggat ttataataga tagggtatta aagtttataa ataaaatcct ttgtagatgg
    22501 aggtttgcag attaatgaag ttaagtgtaa gagatataaa taagacattt gtaaataata
    22561 gagtacatac aaaggtttta gaagatataa gtatggatat agatgatgga caatttgtct
    22621 gtcttttagg accatcaggt tgtggaaaaa caactttact tactataata ggtgggtttc
    22681 aaaaatcaga acgtggagat gtttttataa atgataaaag agttaaaaaa ccgggcatag
    22741 atagagcttt tatatttcaa aattatgctt tatttccttg gaaaactata agaggtaatg
    22801 ttctatttcc tatgaaacag cagaaaatac caaaagaaaa aagagaagaa atgctagaag
    22861 aacttttggt tatgtcagac ttgaaaggaa aagaaaaact gtttccgcat caattatctg
    22921 gaggaatgaa acaaagagtg gccatgataa gagctttagc atgtaatcca gaggtattac
    22981 taatggatga accattagga gctgtagatt ttcaaatgag acaaaattta caggaagagc
    23041 tagaacgaat atggataaag aagaaaataa ctgcattaat ggtaactcat gatgttgatg
    23101 aagctgtata tatgagtgat agagttatag taatgtcgag agataaagga agaattattg
    23161 atgatataaa tatagatatt ccaagaccta gaattagagg aagccaaaaa tatgaagagt
    23221 acaaaaacaa attaactgat actttatcaa agtgttatga agtttaaaga ggagtagaca
    23281 tgagtcaaat agaaaaatac aatagtttgg ataatacaca acagaaaata agaatctcta
    23341 ttatggatat gataatagat aaaggttcta gtgttacact tcaagaagtg actgaatata
    23401 taagtaaaaa gttgaatata gaaaaagaat atatagaaag gacactacaa tattttattt
    23461 ataaaaatat aatggttgtt gatgggaata gtataaattt tatatatcct gtatcagcat
    23521 tgccaacaaa tcataaagta actttgagag ataatagaag tttcagtgca atgtgtgcta
    23581 tagatgctat aggaacctct tgcacattca accaagatat aaaaataaac tctatttgta
    23641 gtgctacagg taaggaaata gaagtaatta taaaaaatga aaagattgag tatgtgaata
    23701 atccaaactt aagagtgctt catataaatc ttgataagca tctaaattgg gctgctagtt
    23761 gctgaaatat aatgaatttc ttctggacga agagtgattt tgatgcttgg acaaacgaag
    23821 cgggattatc taatgatgaa gatatatatt gtttagatat taatgaggca atagtagaat
    23881 catataaaat atttaaactc aaacaaaagg tactatcata gatatacata tatgaaaaac
    23941 taaaaatgac ctttagataa aaatgatagg taatatccat actatataaa ttagtataga
    24001 gtagggatgt gaaaagtatt taaatctaaa ggtatatttt tagttttttt tagatgatta
    24061 gatagcctta ttaagtatat atttatttat aacctttgca actccatttt cattattagt
    24121 atcagtaaca taatctgcaa tttcctttat actattacgt gcattcccca tagccacacc
    24181 aagacctgca tactttatca tatgttggtc attttcttca tcgccaacag caatagcatt
    24241 ttctataggt atatttagat tcgtacataa tgttttaaga gcagttcctt tattagtagt
    24301 tttacctaaa aattctagat aaaaaggagc agaccttact atagtatatt tattgaataa
    24361 atttttaggt agttgctgta tgatttcttc caatctttct ggttcatcaa ctatcataat
    24421 tttacagatt ttaatagatt catcaatttt atctttttgt atatatttga cttctatatt
    24481 atttaatttc gcttcatgaa gtgtatattt gccaggcgtt tcatttggtg taattaaatt
    24541 tgtcattgta tttatgtgta ttttagtctt atatttttta caaacgttat tatatataaa
    24601 atcaaaatca tctaaactca tttctacatc atgtatgatt ttctcacttt taacttcttg
    24661 aataattgct ccattaaagc atataacata atcaccttca tctgttaaat ttagttgatt
    24721 tagaagttct tttacaccag gaagaggtct gcctgttgtt ataactactt ttgccccagc
    24781 cctttttgcc tcctgaatgg actcaaagac ttcaggagta atcctttttt gtgtatttaa
    24841 tattgttcca tcaatgtcta gtgcgattaa tttgtacata tcaacctcca ataaattata
    24901 tactcaaatt tcctgtgaaa acgttgacac agctagtgtt gaacaaagtt tcagtgggaa
    24961 atatggtttg ttttgtatac tattatatca agagataagt aatttagaaa gtttaataat
    25021 attaattttt tgataaaaat attacttatg tgagatgaga atgtaaaaac tttgtaatca
    25081 ataattccaa aattcttaat tacaaataat ggtatcgttt gcattgttaa tataaataaa
    25141 tgtatattat atagttagaa gtttgaataa atagactgat ggtaatttgt tatattagtt
    25201 agttttgtgt tataaaatat tgtaattcca ttaatcatat gttattattc aacatgatta
    25261 taatataaag aatatttgat atatataata atttataaaa gagtattaca tagtacatgt
    25321 aaatctatat ttataaatac aataaagtaa agttgtaaag gagtgcttta aatgaagttt
    25381 tcagagttta agtatgaaag acccaattat aatagtatga aaaaagagtt tttgagttgt
    25441 gtagaagata taaataattc tcgtaattat aaagagcaac aaaaaaatat acataagatt
    25501 aatttattaa gaaataaaat agaaacgttg tcaaatatag cttcgataag atatagtaca
    25561 gacacattta ataaattcta caaagaagaa aaaaattatt gggatgaata tatgcctttg
    25621 tatgaagaat taaattcata tttttataat gccattgtaa attcaaaatt taaatatgat
    25681 ttgataaaag agtttggaga gcaatttttc acaatagtag agtattcttt aaaaagtttt
    25741 tccaaagaaa taataagtga attgcaggaa gaaaataaat tgtgttcaga gtatactaga
    25801 cttttagctt cagctgagat aatgtttgat gggaaaataa gaaatttatc tggtatgggg
    25861 aaattcatgt attctaagaa tagaaaaaca agagaattag caaacaaagc atattataat
    25921 ttctttgaag aaaatgaaac taaatttgat gacatatttg ataaattggt taaacttaga
    25981 gataagatgt ctaaaaaatt aggttttgaa gattttgtag agcttgggta tgttagaatg
    26041 atgagaagtg actacagaga atatatgata aaaaatgtta gaaaacaagt actaaaatat
    26101 gttgttccaa tggcaaatga gctttatgaa aaacaagcta aaagaattgg tctagaatat
    26161 ttaagttaca tagatgaagg cgtggaattt ttaacaggaa atgcaagttt aaagggagat
    26221 tcaagataca taattaaaaa tggtaaaagg atgtattctg aactgtcaaa agaaacaaat
    26281 gaattttttg attttatgtt agaaaatgaa cttatggatt tagaaacgaa gaaaggaaaa
    26341 ggagctggag ggtattgtac ttatatacca gattataagt caccattcat tttttctaat
    26401 tttaatcaaa ctgctgatga tatagatgta ttaacacatg aggcaggaca tgcatttcag
    26461 ttgtatatgt ctagatggat tgatatgcca gaaattaatt ttccaacgct tgatagttgt
    26521 gaaatccatt caatgagtat ggaatttata acatggccgt ggatggattt attttttaaa
    26581 gaagatacag ataagtacaa attcactcac ttatcatctt caattaaatt tataccttat
    26641 ggagtaattg ttgatgaatt tcaacactat atttacaaaa atcctaatgt agataagtca
    26701 aaacgaaaag aaatctggag atttttagag aaaaaatact tacctcatag aaaatatggt
    26761 gataattctt ttttagagag aggttgttgg tggtttaaac aaggacatat atttaaaaat
    26821 ccgttttatt atatagatta tgtattagct caaatttgtg cgttacaatt ttggaaaaaa
    26881 atgattcaag atagagatgc aggatggaaa gattatataa atatctgtaa agttggagga
    26941 acaaaatcat ttttagatat tgtgagtatg ggaaatttgt attctccatt tgatgatggc
    27001 tgtattgagt ctattatagg tgatgttaaa tcttggtttg atgaaataaa tgacagcaaa
    27061 ttataaaaaa ttatgagaat tttattgtat aaaagtgaaa aattaaaaaa tatataaaaa
    27121 gtgattattt gttgtgaaaa tagtcttgtt tttaactaaa ttgataaaat aaactaaaaa
    27181 agatttgtac ttaaaaaaaa aagaaaatac aagaaatatg caatatcaac atttggaaaa
    27241 aaaagtaaaa atgtatacaa aatacatata aaaaaactat tgcaaatttt atagaatgtt
    27301 tatatactta agtcaacaga gatagaaaaa agctatttat agaaaacaaa ggataaattg
    27361 cttaatttta aattttctga aaaaaataat aatccggatg aagagtatgg gagactgctt
    27421 tataaaaagc gaccgaaggg acaagtttaa tcttacttac ccaaaagatt agatgaaatt
    27481 ctcaggtaaa ggtgactgta cttggacggg gctctgaaaa tgattttaac agggaagaca
    27541 aattgggaga tttgtttttc ctgtttttta tttatcaagt aataaataaa agtttgaaag
    27601 agagtaaaaa aatgataata attacgaata atccaaaagt aaaagaagaa gttcaaggca
    27661 gagaagtttt gtttaaagac acaacttata ttggaatctt agaagcaagt agagatttga
    27721 tacatgaagg ttatgaactt ttatctcatc cactctatgg gagtgtaaag ccaaatgaaa
    27781 caccttacag gactgttata ctaaagaaag gaaatcgttt ggatataaac tctttaacct
    27841 taattgaaga agcaatcatc actgcaagta aatttcagaa taataaaaag actccaaaat
    27901 ggacagaaag tgttcaagat gattttagag taattgatta tgatatattt tataatacaa
    27961 tacaaagaat gcagtatgaa taaaaaaaaa ttgttaaaaa gttattaaaa cagcctaaat
    28021 attaaatcta atttaatatt aaataaaatg agaaatttaa ttggggagga taagtcaaaa
    28081 tggaaaatgt gtatgactta gtaataattg gttcaggacc agcagggctt gcagcaggtc
    28141 tttatggagc aagagcaaag ttaaaaactc taatcctaga aaaagacaag actggtggac
    28201 aaattgtaat aacacatgaa attgcaaatt atccagggtc agttccaaat gcaacaggac
    28261 caagtttaat agctagaatg gttgaacagt gtaaagagtt tggagcagaa atgctaagag
    28321 acaacattgt tgatactgag ctagatggag atataaaagt tttaaaaggg gaaaaggcag
    28381 aatatagagc aaaagcagta ataataggaa caggagcaac accaagaaag attggttgtc
    28441 ctggagaaaa agaacttact ggtaaagggg tttcatattg tgcaacttgt gatgcagatt
    28501 tctttgaaga ttttgaagta tttgttgtag gtggaggaga cagtgcatta gaagaagcaa
    28561 tgtatttaac taaatttgct agaaaagtaa caattgtaca tagaagacaa ggatttagat
    28621 gtgctaagag tgttgaagaa aaagcaaaag ctaatccaaa gatagagttt ttattagata
    28681 cagtaattga agaaatcaaa ggtgatggaa tattagaatc agttgtattt aaaaataaag
    28741 ttactggaga aactcatgaa tactttgcag atgaagaaga tggaacaatg ggagtatttg
    28801 tgttcgttgg attagatgct caaactgatt tattcaaagg taaagttgat atggatgaaa
    28861 aaggttacat aataactgat gaagatatga gaactaacat accaggcgta tttgcagcag
    28921 gagattgtag atctaagact ctaagacagg ttgtaactgc aactaatgat ggagcaattg
    28981 catctatagt agctgagaaa tacattgatg aaaaatttgg gaactagaat ctgtaaatta
    29041 agaaatagtg tctgtaaatt taatgaataa tatttaaaat taaaattaat atttaaaatt
    29101 aaaataaaaa tttcaagggg gaataagaaa atgttagatt tagataaggc tacatttgaa
    29161 gaagaagttt taaatgcaga aggttttgta tttgttgatt tttggagtga aggttgtgag
    29221 ccttgtaaag ctttaatgcc agatgttcat aaattagctg agacttatgg ggataaaata
    29281 aaattctgta agatggatac aacaaaagct agaagattag ctataaaaca aaaagtatta
    29341 ggtcttccaa ctatggctat atacaaagat ggagaaaaag tagacgaagt tactaaggat
    29401 gatgctacag ttcctaatat agaaaacatg attaaaaaat atctttaata tgttgataaa
    29461 ttattaacat taaaagaaaa aatctatttt tatctgaaga taagaagaaa aaggttttta
    29521 tgtccaactt tgttaaaaaa ataattttaa ataaaataat ttttttacaa taaatatttt
    29581 ttagtaataa aataaagatt taaggcataa aaacacaata atatatcttt aaaaaaataa
    29641 gataaattgt aaaatgatat aattttgaga aaaactcaaa tgcatataca caaattaaat
    29701 aacaggaggt gcaagtatgc gtcttgaatt agggaaaatc tttataaaag atattcaatt
    29761 tggtgatgta acagaagtaa aagatggagt attattcatc aataagcaag agatgctaca
    29821 agaaattggt ggagatgagc atattaaatc tatagatata gaattagctc gtccaggtga
    29881 aagcgtaaga ataacacctg taaaagatgt tattgagcca agagtaaaag ttgaaggtaa
    29941 tgggggaatc ttccctggta tcatgtctaa agttgacact gtaggagaag gaaaaactca
    30001 tgctttaaaa ggtgtagctg ttgtaactac tggaaaaata gtaggtttcc aagaaggtat
    30061 aatagacatg actggagaag gagctaagta cactccattt tctaaattaa ataatgtagt
    30121 agtaatagct gaacctattg atggtttaaa acaatacgct catgaaaaag ctgttagaat
    30181 gataggattc aaagcagcaa tgtacttagg agaagtagca agaaatctta ctccagatga
    30241 agtttcagta tatgaaacta aacctcttct tgaatcaata aaagaatatc cagagcttcc
    30301 aaaagtagga tatgtttaca tgcttcagac tcaaggttta ttacatgata cttatgtata
    30361 tggagtagat gcaaaacaaa tagtaccaac tttattatat ccaacagaat taatggacgg
    30421 agcaattgta agtggtaact gtgtttctgc atgtgacaaa aacccaagtt atgttcatat
    30481 aaacaatggg gttgttgaag acttatatgc aagacatggt aaagatataa actttgtagg
    30541 tgtaattata actaatgaaa atgtttatct agcagataaa gaaagatctt caaactggac
    30601 ttctaaatta tgtaaatatt taggattaga tgcagttata gtttcacaag aaggttttgg
    30661 aaatcctgat actgacctta taatgaactg taagaagata gaaatgcaag gtgttaaaac
    30721 agttatagtt acagatgaat atgctggacg tgatggaggt tctcaatcac ttgcagatgc
    30781 agatgtaaga gctgatgctg ttgtaacagg tggaaatgcc aaccaagttg tagttcttcc
    30841 taagttagat aaagttattg gacatttaga agtagtagat gtaatagctg gtggttctga
    30901 tggaagttta agagctgatg gaactattga agttgaaatc caagctataa caggtgcaac
    30961 taatgaaaca ggatttggtc atttaactgc taaaggatat taagaagtat tttattaaac
    31021 gattgagtaa tgttaataaa acatattata gataattata ataagtgtta tagatatata
    31081 aaaatatatt agaaatataa taaggaggat tattatgagt ttacttagta ataaaaaggt
    31141 tcttataata ggtgaccgtg atggtatacc aggacctgcg atagaagaat gtgtaaaaac
    31201 agtagaagga gcagaggttg ttttctcatc tacagaatgc tttgtctgaa cagctgctgg
    31261 ggctatggac ttagaaaatc aaaacagagt taaagatgct gctgataaat tcggagctga
    31321 aaatgttgtg attttactag gtgctgctga agccgaagct gcaggtcttg cagccgaaac
    31381 agtaactgct ggagatccaa ctttcgctgg accacttgct ggagttgcct taggattaag
    31441 tgtttaccac gttgttgagg aaccaataaa atcattattt gatgaaagtg tatatgaaga
    31501 ccaaataagt atgatggaaa tggttttaga agttgaagaa atagaagaag aaatgtctgg
    31561 tataagagaa gaattttgta aattttaatg cctaaaagca aaaggggtga aactaagaga
    31621 tgggaaaact aaaagcagta cattatatta atcagttctt tgctggtata ggtggagaag
    31681 aaaaagctga tactaagcca catgtggcag aaactttacc tccaataagt ttacaacttg
    31741 ataaattatt aggtgaagat attgaaatag ttggaacagt agtttgtgga gatagctatt
    31801 tcaatgaaaa tatagatagt gcaagtgaag aagttttatc aatggtaaaa ggttttgaac
    31861 cacaactttt catagctggt cctgcattta atgctggtag atatggggtt gctgctggaa
    31921 caataactaa agttgtaaaa gatgctttga atataccagc tttaacaggt atgtatgttg
    31981 aaaatccagg agcagatatg ttcaaaaagg atgtttatgt agtagaaact tctgattctg
    32041 cagcaggtat gagaaaggca cttcctaaga tagctaaact tgcagtaaaa cttgctaatg
    32101 gagaagaaat tggaactcct aaagatgaag gatacatagc tagaggaata agagttaact
    32161 acttccatga agacagaggt tctaagagag ctgttgacat gttagttaag aaaataaaag
    32221 gtgaaccatt tgaaactgaa tacccaatgc caaactttga tagagttgac ccaagtaaag
    32281 ctgtaaaaga tttatcaaaa tgtaaaatag ctttagttac ttctggtggt atagttccaa
    32341 aaggaaatcc agatagaata gagtcttctt cagcttctaa atatggaact tattctatag
    32401 caggagttat ggatttaaca gaagagactt atgaaactgc acatggtgga tatgacccag
    32461 tgtatgcaaa tttagatgca gatagagtat tacctgttga tgttcttaga gatttagaaa
    32521 aagaaggtgt aattggaaaa ttacatgaga ctttctatac aactgtaggt aatggtacat
    32581 ctgttgcaaa ctctaaaaaa tatgcttctg aaattggagc agcattagtg gctgatggtg
    32641 tagatgcagt aatattaact tctacatgag gtacttgtac tcgttgcggt gcaacgatgg
    32701 taaaagaaat agaaaaaact ggacttccag tagttcatat gtgtacagta gtacctattt
    32761 cattaacagt aggggctaat agaatagttc caactatagc aatacctcat ccacttggaa
    32821 atccagcgct tgaccctaca gaagaaaaag ccctaagaag aggccttgta gaaaaagcat
    32881 taaatgcttt aactacagaa gtagatggtc aaacagtatt tgaaaaataa aaataacaca
    32941 cacatatatt atatagataa aaatataaac acacactaaa aataaaaaat aactatacac
    33001 aaaaaaataa tatagatttc atgaatggat aaattggagt tattcattca tgaaatctta
    33061 aaaaatgcca aaatacataa acaataatag aatcaaatat acaataaaat acaatgatta
    33121 gagcttttaa taagtttaat aagattaaaa aataagtgtt cataaaattt atggaggtgc
    33181 acaaaatgac ttatccagtt ttaaaagggg caggctatgt acttattcat actccagata
    33241 tgatagtgca aaatggaagt acttgtacag ttgaaagagc aacaaatcca gattcagaat
    33301 ttttaaaaga agtaagtaat catataagaa gttatgaaga tgtagttaac tacatgccaa
    33361 atcaagttta tataggaaat agaagaccag aagaattaag agatttacca atgccatggt
    33421 gtgaacaaaa gattgaggga actagaaatg gtaagtttgg agaaataatg cctcaagatg
    33481 agttcatagc tttaatgcaa ataagtgatg catttgattt agtaaaatta tcacaagaat
    33541 ttattgatga agtaaagcca aaaatcgaaa ataactaccc tgaaattgca ccatttgtag
    33601 gtaaattaaa gggtgatgat atagaagaag gtaaagaatt agtagcaaca cacatagctg
    33661 aaggattata ccatgatgga aaatttgttg gttatgtaaa aagagcacat gatgtagatg
    33721 ttaacttaaa tgcccataca atgtttgaaa atctagtagt aaaagcatct ggagttttat
    33781 ctgctattca aatgctaaga catagcaaaa tagaccctgc tgaaatagat tatgttattg
    33841 agtgttcaga agaagcttgt ggagatataa accaaagagg tggaggaaac tttgctaaat
    33901 caatagctga gatagcagga cttcaaaatg caactggttc tgacacaaga ggattttgtg
    33961 cagcaccaac tcatgcatta attcaagcag cagctttagt aaaagctggc atacataaaa
    34021 atgtaatggt agtagcaggt ggagcaagtg ctaaacttgg aatgaatgct aaagaccatg
    34081 ttaaaaaagg tcttcctgta cttgaagatg ttgttggagg atttgcagta cttgtatctg
    34141 aaaatgatgg tgtaaatcca gttataagaa ctgatttaac aggtaagcat actgttggaa
    34201 ctggttcttc accacaagca gttatgacag cacttataac ttcaggtctt gatagagcta
    34261 atttaaaaat aacagatgtt gatgtgtatt cagttgaaat gcaaaaccca gatataacta
    34321 agccagcagg agcaggagat gttccagaag caaactacaa aatgataggg gcacttgctg
    34381 ttaaacgtgg agacttagaa aagaaagaat tgaaagattt tgtttctaac aaaggattac
    34441 caggatgggc accaactcaa ggacatatac catcaggagc tccttatata ggatttttaa
    34501 tagatgattt aactacagga aatagaaata gagctatgat agttggaaaa ggtagtttat
    34561 tcttaggaag aatgactaac ttatttgatg gagtatcttt tatagctgaa agaaatacag
    34621 gtgttactga agagacttca ggaatatcta aggatgaaat taagaagata atagctgaat
    34681 ctatgaaaaa actagcatta gatatgttag aagaataggg gtgaggatat gtcaaaaaaa
    34741 gtaatcgcag atgtattctt agaagtagct aatgcaatag aaagcggcga atttggcaaa
    34801 aaagtaaaaa ttggtgttac tacacttgga agtgaacatg gtgtagaaaa catggttaat
    34861 ggtgcacaat tagcaaaatc taatttattt gatattgtgc ttattggacc aaaagtggaa
    34921 actgaccttg aagtagttga agttaatgat gaaaaagaaa tgcatgcaaa aatggaagaa
    34981 ttattagatt caggatatat tgatgcttgt gttactatgc attataattt tccaataggt
    35041 gtatctacag taggtagagt aataactcca gcaaaaggaa aagaaatgat acttgcaaca
    35101 acaacaggaa caagtgctac taatagaata gaggcaatgg taagaaatgc catttatggt
    35161 attgctacag ctaaatcaat gggtaacaaa tgcccaaaag ttggaatact taatgttgat
    35221 ggagcaagac aagttgagaa gtgcttaaaa gaattaaaag ataatggata tgacatggag
    35281 tttgcggatt caattagagc agatggtgga tgtgtaatga gaggtaatga tttacttgta
    35341 ggtgcacctg atgttatggt tactgataca ttatctggaa atatatttat gaaagtattt
    35401 tcttcatata ctacaggtgg agattatgaa gctcaaggct ttggatacgg acctggagtt
    35461 ggagaggact atgatagaaa ggtacttata gtatcaagag catcaggttc tccggtagta
    35521 gcaaatgctt taaaatacgc ttatgatgtt gtaaagggag atataagtaa tgttgcaaga
    35581 aatgaatttg caaaggttaa aaaagcaaaa tttgatgaca ttatatcctc tcttactaaa
    35641 aaagaagtta aagctgaaaa agtagaagtt aaaatgccag ataaagaaat tgttactcgt
    35701 caaatagctg gtgttgatat aatggattta gaagatgcag tatctgagtt atggaaaaac
    35761 ggaatctatg ctgaaagtgg tatgggttgt acaggtccaa tagttttagt aaatgaagct
    35821 aaaggagact tagcagttga aactttagtt aaagctggat atactgcaaa ataagtacat
    35881 tttttatatg taaataagaa catatagtta taattttatt gattataatt atatgttctt
    35941 tttattttat atcttgtcaa tatttatata ttaacacaat ccatttattt gattctctag
    36001 ctaatttatt atatttattc aattaaaatt aagctttcta actaaataaa aactaatgaa
    36061 gtattaaaat gaaattgata aaatatgaaa aaattttagg aataaagtat ctgttagata
    36121 aaaataagat taattagtga tataatataa ttaagataaa atttattatt tggaggtaaa
    36181 atcatgagca gagtaaaaaa tgtagtagaa ttgttggaaa ctaaaggtgt tgatgcacta
    36241 tatctaacaa agaaaactaa tgtaaactat ataagtggtt ttcctgatga agaagcatat
    36301 gcagtgattt gcaaagatgg aaacttttta gttactgata gtagatatat ggagcttgca
    36361 gaaaaggttt gcaaagattt tgaaattata aattggcata attttgatag aagtgtggca
    36421 aaggcagtta aaagtgtatg tgataaagtg ggtataaaga aacttggatt tgaaagaact
    36481 aatatagtgt ttgataaata tgaagaactt aaaaatctga ttgagaagga taatggagaa
    36541 ttaataccta cagaaaatat tgtagagact ttgagatatg taaaagacaa agatgaaatc
    36601 aaaaatacaa gaaaagcttg tgaaatagcg gataaggcat tagaagaatt gattccacat
    36661 ataaaagctg gagttagcga aattgaactg gctacaaggt tagagtactt tatgaaaatg
    36721 aacggagcac aaaatatagg gtttgaaact atactgatat caggagcaaa gacttcattg
    36781 cttcatggta agcctagtga taagattata gaaaaaggtg attttgtact tatagactat
    36841 ggtgctatgt ataatggcta tatatctgat acaactagaa cttttatagt tggaggagct
    36901 tctgaaaagc aattagaaat atataattta gttaaggaag ctcaaaatgt aggggttgag
    36961 aacatgaaag ctggtgtaca tgcgacaatt ccagatgctg agataagaaa agttgtcaaa
    37021 aaatatgaag actattacta tcaaggtata ggacatggag tcggtagaga tgttcatgaa
    37081 gaacctttca ttggtaatta tggtgataaa atcatagaag agggatgtat aataacaatg
    37141 gaaccaggta tttatttccc tggatggggt ggagttagaa tagaagatac tgttttgatt
    37201 actaaaaatg gtccagaaag acttactaaa ttccctaaag atttgatgat tttagacaaa
    37261 taatttaatt tatatatatt tttttacata aaatataaca taatctcact attaagctct
    37321 atttacatat tatagtaaag agggcttaat tttattgtga gaggtgatag tatatatgta
    37381 taaaaaacat aaatttataa aaaatataaa aaaagcctgg tataaaatca aattaattga
    37441 tagatgcctt ataattgtaa tggcaatatt aatgtttcaa tctatatata acttatttgt
    37501 taatgaagta aattcacaag atactacaac tattgatgta gtagtaagaa ccacttcagc
    37561 agctatattt gggtattttt taagtgctaa ttttataaag agacctttaa ggaagtatac
    37621 aaatactgat gtatcttcaa atctttttat agataataat ttatccccaa aaggtcaaga
    37681 gtctaatcaa aataatataa tgaatgtcaa aaataccatt ggatttactt cagaagctga
    37741 taattatgaa aagaaaatac ctattaataa taatgaaggt tttgaagaag gagaaactag
    37801 tgaattgcaa attattatag ctactgtaat ttgcatagta gcattaacag tactttttgt
    37861 tgtaagaaat tttacaacta caacatcagc ttctttaggt actatttcac agatgagaga
    37921 ttttgtctca ggatgcgtgg gttttttgct aggttgtcca agtaaacctg attaaaaaag
    37981 tattatcaat aaaaggtatt ttaaaaagta tcagtataat aatatttaga tttaaatgta
    38041 tacaattata attctgtaac attctatatt gtatttttat actgatactc taaactatac
    38101 tatttattaa aatattttaa cattgt
//
LOCUS       DAEPKC010000029        38088 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.029, whole genome shotgun sequence.
ACCESSION   DAEPKC010000029 DAEPKC010000000
VERSION     DAEPKC010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 38088)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38088)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38088
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.029"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(484..1638)
                     /gene="nagA"
                     /locus_tag="KR294_001537"
     CDS             complement(484..1638)
                     /gene="nagA"
                     /locus_tag="KR294_001537"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HBH0239619.1"
                     /translation="MKSFIYADKFFMKHGIKEKGYLSIINGKFGEFQQERPNVTDNVI
                     DFSGKYIAPGLVDTHIHGLLGADVMDNTFEAINTISKGLLKYGVTSFLPTTLTDSVDT
                     LSDSVENISNSFNRVEGAKIQGIYLEGPFFTEKYKGAQNEKYFKDPDINILKLWQKKS
                     KNLIRKIAIAPERKGSIELTRYATKNNISVSLGHSSATFEQVKQVVNSGAKVFVHTYN
                     GMSPLNHREPGMVGAAMVLKDTYAELICDGHHVSPIAVKIMMDAKSSNNIALITDCMR
                     AGAMEDGKYTLGKFNVNVKNSVARLNSGSLAGSVLTMDKAVRNIVDWNIATLEDAIKM
                     ATYIPALSCNIDNVCGSIHQGMEADFIVTDKDFNIYETYISGICKYKVNK"
     gene            complement(1721..2446)
                     /locus_tag="KR294_001538"
     CDS             complement(1721..2446)
                     /locus_tag="KR294_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH0239620.1"
                     /translation="MIKRNDKRPIYDQLVEILRTKIENEMEPNDRMLSERKICDEYGV
                     SRTTVRLAMAELEHMGYIYKRHGKGTFVAALSQNSQNLMESYSFTDYMRTQGKKPGTK
                     VLSFEVVESTKYFSEKLGITPGEKMIKIMRLRLADDLPMMLERTYLPMKEFIGLTKEK
                     IEQKPLYEIFREDYGEIIKVADEEFSAGIISDKEAKLLEVPGDSPCLKLLRTTYNDDN
                     IVIEFTLSVARSDKFVYRVRHVR"
     gene            2713..3642
                     /gene="pfkB"
                     /locus_tag="KR294_001539"
     CDS             2713..3642
                     /gene="pfkB"
                     /locus_tag="KR294_001539"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HBH0239621.1"
                     /translation="MITVITFNPSIDRMYRVNNINIGEVQRVVSKNATAGGKGLNVSK
                     VCKILKENPLAMGFLGGFNGEFIKNELRKLDIQNKFTKIEQETRNCLNIIEDNKVSTE
                     FLEKGPIVEKSDLERFENDIEEVLKNTKILVASGSYCENMPIDYYEKIGNICRANNIK
                     FILDTSGEALKIALKSKPYLIKPNIDEIRHLLGINIESREEIILSGKKLIEMGAENVC
                     ISLGKDGMVYLNEDNVYYVKVPVVKCINTVGSGDSTVAGFSVGILRGYKIENLLKFAN
                     ACGISNALNMETGFVDLGEIDKYQDLVEVKKLS"
     gene            complement(3771..4688)
                     /locus_tag="KR294_001540"
     CDS             complement(3771..4688)
                     /locus_tag="KR294_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBH0239622.1"
                     /translation="MKNIKMGMIGLGSIAQKAYLPILTKSERFEFVGAFTPNKVKREK
                     VCSDYRIMQFDSIESLAKKCDCIFLHSSTETHYEIIKILLNLGVHVYVDKPLASTVSQ
                     GEELIELSTKKNLNLMVGFNRRFCPMYKEIKNNATEIVSINICKHGLNSLRNVKFDST
                     LIDDYIHVIDTALWLANEDVEISGEDLFLTDNKNLIFVSHKLKGKNFSINTSMHRDSG
                     TKLEQVEILSKGKIQRVKNLNVLEIEEGGNLTLKQSGAWVNILKQKGFEDISNHFIDC
                     IENNIKPAISGEECIKAQRLLEKIINSVK"
     gene            5158..6327
                     /locus_tag="KR294_001541"
     CDS             5158..6327
                     /locus_tag="KR294_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBH0239623.1"
                     /translation="MKMFKLEEQKLKDLGAIITTNEIKQQPELWLETYEIYKSNKEKL
                     SRFIDTISNNHGQFRVIFTGAGTSAYIGNSILPYLKNKNDIRKYIFEAIPTTDIVSNP
                     YDYLKKDIPTLLISFARSGNSPESLAALNLGNKIVDNFYHLAITCNPEGELAKMTKND
                     ENNYLLLMPSKSNDEGFAMTGSFSCMMLSAMLIFDSLEDDVEKSYINAIVEMGRNVID
                     RKDEIHELINKDFDRVVYLGSGGLGGLTQEAQLKLLELTAGKISTVYDSPMGFRHGPK
                     SFIDENTLVFEFVSNCLYTRKYDLDVLEEIKRDKIAKFTCAVSVENENNFSGTKFEFK
                     EKYNKLPDVYLAMPYILFAQTIALFVSVKVGNKPDTPSATGTVNRVVKGVTIYEY"
     gene            6376..7227
                     /gene="gatY"
                     /locus_tag="KR294_001542"
     CDS             6376..7227
                     /gene="gatY"
                     /locus_tag="KR294_001542"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit GatY"
                     /protein_id="HBH0239624.1"
                     /translation="MALVTTTSMLKKAQDEGYAVGAFNVENMEMVIAVIEAAEELNSP
                     VILQTTPSTVKYAGLDYYLANAKVAAERVKIPVAMHLDHGSSFDLAMKALRSGYTSIM
                     IDGSHESFENNISISKSVVKACSPSLIPVEAELGKVGGKEDDLDGGNSNDYTNPKEAK
                     EFVDRTGISSLAIAIGTAHGLYKGEPKIDLDRLSEIKNVVSIPLVLHGGSGIHDDIIK
                     EAIKRGIAKVNYATELRIAYSKGVKKVLDEDSEVIDPKKYGLAGLQSVKDFVKEKIKV
                     CGSVNRV"
     gene            7553..9454
                     /locus_tag="KR294_001543"
     CDS             7553..9454
                     /locus_tag="KR294_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBH0239625.1"
                     /translation="MRERIILETLKNSSGYLNIDYFADKLGVSTRTIRNEIKKIETIK
                     ECNGFKLEYKSKLGYILNIKDQDKFEHYLRNLPSDLVENPEQRLESIIVELLVNEGYK
                     TIEQLSKKFLVSSSQIKNDLKKIDEKIKDTELKLERKAHYGIKIEGSIKEIQSILVDS
                     YFRGNRNITEYRNKFIDNLKLANIRSTIKNVLNEHDLEANLTELEEILAQIIILYIRV
                     SMRVAGNASDLKLYTEDLIIDKLLDKIFRDKKYNLNYDEKYYLKELIKLKTKDKKATI
                     KNIDKNKLQDIMFEFFREIDKKYNSNFLEDKEFFNLFYLHIACLIERIKKNHKIINPF
                     SVKISQQYPTVFNLSIQFSKIIENEYHIKISQDEIGFIATHIAVPFEKREEANFNKKY
                     KIAIICSSGGGSAFLINLRLKEIFPNAEIRNFSLLEEKAVIEFAPDLIFSITNLLFEI
                     NAPVILINEILDELDYLDIKESVRFADHIGNISSPKQYILGLFDKNHFRCIKDKAKYK
                     DILDSMSKCIVDEGACSPTYPKDVWERESYLSTIYTNGVAIPHPIEMTGNKNIISVAL
                     IQTDIIYENRVPKIIFMISLIKGNLELHKQISKYLSKIMANKDMVDMLNKSQSYEEFM
                     YKLKIYLGG"
     gene            9457..10500
                     /gene="ypdE"
                     /locus_tag="KR294_001544"
     CDS             9457..10500
                     /gene="ypdE"
                     /locus_tag="KR294_001544"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HBH0239626.1"
                     /translation="MNIEFFKRLSEADGIASNEEEVRHVLLEELKAYSDKIICDGLGS
                     IIFSKIKDESAPNVMICAHMDEVGFMVRSIDKLGMIHLITIGGVKPLAQFVQKVRITT
                     KEGKKIPAVINATYNNGKAENIYADIGAYTEEDVYNLGINVGDMVTYTTSFEEFTLPD
                     RLVGKAFDDRIGCFVMGEVLKELRKENLNCNIHFAATSSEEVGIRGAKTSTQLINPDI
                     VFVIDVACAKNEFVRDYTNQKQIDKGVMLMHRDRTLVPSRKMIDYVMEIADKNNIPLQ
                     HDMFESGGTDGGEAHLVNEGKPCVVTCVPVRYGHCAFSIVSNKDLENIIRLYTQLILN
                     FDEEQYKHIRNFI"
     gene            10515..10820
                     /locus_tag="KR294_001545"
     CDS             10515..10820
                     /locus_tag="KR294_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBH0239627.1"
                     /translation="MSTEVQIMELISTAGESKSKAFEALKKVKSKDFKGAKLLIEEAR
                     KIDIEAHRIQTELITQDLNEDVESPAMSLLMVHAQDHYMTSQLAKDLIEALIYCLDK"
     gene            10917..11252
                     /locus_tag="KR294_001546"
     CDS             10917..11252
                     /locus_tag="KR294_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH0239628.1"
                     /translation="MKILLCCAGGFSTNMLMQNMKKVVKESAKLNEKDFEFTAIPADS
                     IESEVDDWDIVLIGPQIAHKIDFLKGILEPKNKPFAVIDKDVYGKMDGATVMKLALIT
                     YKKHQLAQG"
     gene            11284..12606
                     /locus_tag="KR294_001547"
     CDS             11284..12606
                     /locus_tag="KR294_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH0239629.1"
                     /translation="MFSKFEAFMNRVFMPLAHKVDNQRHLGSIKAGMVAMTPFTILGS
                     IFAILPALPNMLGENNPISKFILNNSAILDLPVSLSIGLIGLYACMCIAFNLGNYYKL
                     YIPGCVALSTFSFLFLVASFTPDGALEIGNLGAKGLFTGMIAGLGSVELYNFCNKKNI
                     TIKMPENVPDFVSRSFELIPTTIIVCGTFIVARFISLKVFGELPPQILTQFLSPLVGS
                     MDNPWSVLALNFAICTIFFFGIHSSVFSPITRPIMITFIAENIAAMQAGETIPHFFTA
                     GASSAFFGFTGCGISIGCVIACMLSKNASYKKIGRVSLFPALFGINEPILFGAPIILN
                     PIMFIPHVFGGAIIGTLPMFFMHWGWLAKPVFDPPYVGVFLEGFLTNGDWHSILANAL
                     QLVLAVLLYWPFFKIMERQQNNKKQKEETKNIFSKEEEDLLDDLGLDF"
     gene            12616..13686
                     /locus_tag="KR294_001548"
     CDS             12616..13686
                     /locus_tag="KR294_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBH0239630.1"
                     /translation="MNNTMERLVSLIYKRGVDALLIKAKNTKRYIGALSGSGVYVLVT
                     KDKNYQILDGRYIDEADKKTTGFIKRIVSQGSYIPTIIELLKELNIKKLAIENQAMSI
                     QEYLSLKNEGFEINLITNELWKLRAIKSKEEIELIKKACEITDEVFDEVISEIKKDMT
                     ELEVSALIQYHALKKGASGMSFETIVVSGERGAMPHGRPTNKKLKVNEAITIDFGVVY
                     QGYQSDMTRTISIGKPPKIIKEIYDVVLEAQLSAIESIKEGTRASDVDKVARKIIDKH
                     GFGEYFNHGLGHGIGLGDGEVPTLNPNSEDILVEGMVMSCEPGIYIPNVGGVRIEDDI
                     VIIDGKGVPLNKTSKEFIILGE"
     gene            13691..14878
                     /locus_tag="KR294_001549"
     CDS             13691..14878
                     /locus_tag="KR294_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBH0239631.1"
                     /translation="MKYNFNKVLNRKEGNCRKWSNHVIKEKFGLNEDAIPMDLADIDF
                     ECAPAIKESILKRASVGDYSYTFIGDDFYDAIINWNKRRFDVYIEKDWIKLTFGTVST
                     LHYIVQAYTKEGEGVLINTPAYDPFAEAVVNNNRKLCCSSLKLDNNRYYLDLEDMENQ
                     MKYENIRLLIFCSPQNPSGRIWTKEELYQVSELCLKYNVILVSDEIHRDIIFKDYRFV
                     SLWNAHPEIYKNSIICVSPNKGFNLGGLKTSYVLIRDVKIRETLLERLKSNSITSPNV
                     FAIPAIVAAYNESEEWLDAMTSYVEENFEIVYDFFETNIPKAKVMKSDSSFLAWIDVR
                     EVFRNEEESKEFFRHANLTMVVGSYFVKDGDGFIRINVGCPRETLNEALNRIKKTYIS
                     MYC"
     gene            complement(15075..15947)
                     /locus_tag="KR294_001550"
     CDS             complement(15075..15947)
                     /locus_tag="KR294_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HBH0239632.1"
                     /translation="MNILQNENLIIESSSFGAELTKIFSKKYDKNILWDGNKKYWGRQ
                     SPILFPIVGKLFDNETIIEENLYSMTQHGFARDMDFEIVDKGDTFVTYKLTDNESTLK
                     KYPYSFELIINYTLNDNSIEVEWIVKNTDSKDIFFSIGGHPAFNLPFYEQNDFSKHYL
                     EFKSKNDVEKINLNGSFTDDIIPIGKLKNLQLNPEVFKNDALIYTNIDEVSICNNDGS
                     KYVTISMEDFPLVGIWTPYYSETNSTAPFLCIEPWYGLADSINSNKIYKDKKFINKLS
                     KGKVFTASYNINIH"
     gene            complement(16341..16532)
                     /locus_tag="KR294_001551"
     CDS             complement(16341..16532)
                     /locus_tag="KR294_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239633.1"
                     /translation="MDDFSKLKSLYEDGYRCIYHDCVDNNYTIYLKNFYTEGSETIEL
                     SSESDFSQFKDYIDGLRMS"
     gene            16752..17798
                     /gene="cobT"
                     /locus_tag="KR294_001552"
     CDS             16752..17798
                     /gene="cobT"
                     /locus_tag="KR294_001552"
                     /EC_number="2.4.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide--dimethylbenzimidazole
                     phosphoribosyltransferase"
                     /protein_id="HBH0239634.1"
                     /translation="MSLLESISKNIYSLDNSSIEKTKQRLDRLIHPTGSLGKIEDICM
                     QLAGIFGNENFDTSKKVIIAFAGDHGVYEEGVAPDPQNITKLQFPNFSKGLCGVGVIS
                     KFVGADVVAVDVGINCDEKLDGVLDYKIRKGTSNMAKGPAMSKQEAIRCLEIGIEIAE
                     QCIEKDYKVIGIGEMGIANTTPSTAIISVISGCDPLEVTGIGAGLKKERLKHKAEVIR
                     KAIEINNPNPTDGVDILSKVGGFEIGSMAGVILGCSANRIPVVIDGFISYAAALIAYK
                     INPKTREYMIASHLSAESGTKRALDILKLDPLLNMDMRLGEGSGAALAFDIIEASNYT
                     YKNMATFDEIDMGR"
     gene            17830..18390
                     /gene="cobU"
                     /locus_tag="KR294_001553"
     CDS             17830..18390
                     /gene="cobU"
                     /locus_tag="KR294_001553"
                     /EC_number="2.7.1.156"
                     /EC_number="2.7.7.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional adenosylcobinamide
                     kinase/adenosylcobinamide-phosphate guanylyltransferase"
                     /protein_id="HBH0239635.1"
                     /translation="MSKIILVTGGARSGKSNFAEKLCFDRNNNTAYIATSIPFDDEMK
                     DRVKKHQENRPRNWNTYEIYEDIYSIIKEIYKEHETVILDCVTLLVNNLMFEHNLNIE
                     ESSQEEINKLEQYIKEQVVKLIEEIEKTNLYFVFVTNELGMGIVPGNKLSRIYADIVG
                     RINQYIASKSNEVYFVVSGIAMKIKE"
     gene            18400..19173
                     /gene="cobS"
                     /locus_tag="KR294_001554"
     CDS             18400..19173
                     /gene="cobS"
                     /locus_tag="KR294_001554"
                     /EC_number="2.7.8.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobinamide-GDP ribazoletransferase"
                     /protein_id="HBH0239636.1"
                     /translation="MKRFILILQFLTRIPIKLNVGFDDEFYKSIVYFPLVGFVIGILS
                     YLIGWISMLLFEPFIASIIITLAGVLITGGLHIDGLGDTFDAIYSYRDKEKMLEIMKD
                     SRLGTNSLLAIMFVLLLKVGFVYDIISNNSLWVIIFMPMIARLGVMLLTYKTVTPREK
                     GMGNLFIGKLTTSMLITAIIYTLLIVALITKFIFLLPNIVLIKVLGSIIVVFVFIILF
                     KKHIYKKIDGVTGDILGCGIELSELVYLIYIYLLIFMFF"
     gene            19193..19807
                     /locus_tag="KR294_001555"
     CDS             19193..19807
                     /locus_tag="KR294_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBH0239637.1"
                     /translation="MIRLILIRHALTNDNKKGRLSGHINSCISEEGKLQINKITRYLS
                     NENIDKVYTTPSTRTKDTVEKISKLKLLEIEEKEALREISFGDFEGRTFEEIKIKYPN
                     EFEKMIKEGNNYRYPNGESLIDSYKRVAKEIDNIILENDSNLDTKTILICSHAGTIRN
                     IITHLISGSYKYHWNFKIDNASITVLEIDGGFAVIDKMNFTDFI"
     regulatory      19874..20053
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            20183..21682
                     /locus_tag="KR294_001556"
     CDS             20183..21682
                     /locus_tag="KR294_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobyric acid synthase"
                     /protein_id="HBH0239638.1"
                     /translation="MLQGTASNVGKSVLVAGLCRIFKQDGYTVAPFKSQNMALNSFIT
                     KEGLEMGRAQVFQAEAAKIEPIADMNPVLLKPSGNNKSQVIVRGKVVGEMPSSKYHDY
                     KLELVDVLKETFNSLNSRYDIVVMEGAGSNAEINLKDRDISNMGMAEIADAPVIIVGD
                     IDRGGVFASLAGTMLLLNEDEKRRVKGVIINKFRGKKELLQDGVKMLEDIIKVPVIGV
                     VPYTDIKIEDEDSVTTRFKKKMNKSDIHIEIIRTPHMSNFTDFNIFETQEDVSIRYVD
                     YGESLGNPDILIIPGTKSTIDDLTYIRKSGLESQIKNLHSQGKLIFGICGGYQMLGKK
                     LKDPYHVESEIEEVDGIGLLDTETTFEKEKTTTQVEATIVECISEYMNNLKGKKVKGY
                     EIHMGITKRGNDVRSLDLITKKLDKEVNYTEGSVNKEGNVIGTYLHGIFDEISFTRAI
                     LNNIRKKKGLGELESKVNSFNEFKDKEYDKLADFLREHLDIEKIYEIMK"
     gene            21721..23097
                     /locus_tag="KR294_001557"
     CDS             21721..23097
                     /locus_tag="KR294_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobyrinate a,c-diamide synthase"
                     /protein_id="HBH0239639.1"
                     /translation="MKKILIAGTNSGVGKTTISLGIMQALVKRNMKVQPYKVGPDYID
                     PSYHTFITGRHSRNLDSYMLDDEKIKYIVNKSSKDADISVIEGVMGLYDGFGIDLDNC
                     TSSHTSKVLKSPVILVINGKSMAASSAAMVLGYKELDKDVNIKGVIVNNVKTNSHYQI
                     IKSSIEKYCNVEVLGYFPPNNKFSLESRHLGLVPSVEMKSLREKFYTLADEIEHYIDI
                     DRIIEISESDEFESDFDFQTLIENNKIKEHVNNKSIAIAYDKAFNFYYRENIELLEEL
                     GLEINYFSPLEDVSVPNADYIYIGGGFPEIFGKELEANESMRTSILEAHNNNIPIYAE
                     CGGLMYLGEKLLNQEEQEFNMVGIFSGISKMTSSLKRFGYCIGVAKENTLLSKKGESI
                     KGHEFHHSIFESDEKCVYSMRKERDGNIVEEWDGGYSKGNTLATYLHTHFYNNLNCIE
                     NFLKKGNE"
     gene            23098..24069
                     /locus_tag="KR294_001558"
     CDS             23098..24069
                     /locus_tag="KR294_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin biosynthesis protein"
                     /protein_id="HBH0239640.1"
                     /translation="MSILSIYIGYVTDLIVGDPYSFPHPVRFIGKLINFTQGIIRKVS
                     KNDRQLKLGGFILWFITVGITYLTTYAIVKLFSFNILLSIVVNSFIIYTTLATKCLKD
                     EALKIYNVLKTEDIEKSRIQLSYIVGRDTTNLSEPEIIRATVETVAENTVDGIIAPMF
                     YAFIGGAPLAMAYKAINTLDSTVGYKNKKYKDIGFASAKIDDIANYIPARISVILMTI
                     GSFFLNYNYRNCFKISIRDRKNHKSPNCAFSEGAVSGALGIQLGGTNVYFGEKVYKPT
                     IGDKLREIDKEDIIKTNKIMYASSFVSMLVFTLIYVLCRMILINLII"
     gene            24101..25171
                     /locus_tag="KR294_001559"
     CDS             24101..25171
                     /locus_tag="KR294_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBH0239641.1"
                     /translation="MKDLGHGANVDEMARLYGKNPKEIIDFSSNINPNVLPNLERYIL
                     KGLEECRNYPDINYTNLRENISKYIDINPDFIIPGNGATEVIYLLMKSIKKKLAIINP
                     TFSEYRRSAELNNLDIIDLELDLENNFKLNIDIIKENIKRFDSLFICNPNNPSGNVQD
                     LKELVHLLDKHNKVLIIDETFMEFVEDESKYSLVKYIESNKNIFIIKAVTKFFGMPGL
                     RLGYGLTSNTEIMNKIYEHKEPWTINSFADILSNFIFEDKEYIKNSKEYYIEEREYML
                     QELRNIRNIKVYDTDANFILIKIYKKTTKELKKDLFKQGNILVRDASNFIGLDDSFIR
                     VAIKSHEDNKILIENMKNLLGD"
     gene            25173..26060
                     /locus_tag="KR294_001560"
     CDS             25173..26060
                     /locus_tag="KR294_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin biosynthesis protein"
                     /protein_id="HBH0239642.1"
                     /translation="MKSYGICPASCGEFVQGIIDDEEYLCSYAIDMYSKVYIEEKLVD
                     INLGRYKSRLAIEKVFEKFNLPKKYTKNISLNINSKIPVGKGMASSTADIGATIKATL
                     SLIDKDLSSEEISKLAAEIEPTDSIFIDKNSIFNPLNGTVIKYLGNLTNAKVVILEPN
                     KVLDTMKIRLRQDYNKLKVENKEVIKKSFALLEEGLKKNNLSLVGEACTLSSLANENI
                     EKKEYLNEIIKISKKYGAYGVNIAHSGTVVGILIDKFMNDKKMIDALCESNINSVYNK
                     IYTQNIINGGIKGEIEWNT"
     gene            26048..26680
                     /locus_tag="KR294_001561"
     CDS             26048..26680
                     /locus_tag="KR294_001561"
                     /EC_number="5.4.99.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003724727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-8 methylmutase"
                     /protein_id="HBH0239643.1"
                     /translation="MEYIKNPMKIEEKSFELIQEIIDEIRPDYKFKNNIEEKIIKRAI
                     HTTADFDYLDILKISEEAVDSIIDALKNNASIYTDTNMALSGINKRKLESLGCKYKCL
                     VADDETVKLAKEKGITRSMAAVEIAAKEEGRKIFVLGNAPTALYKVMEMKSEGRLDLD
                     AVIGVPVGFVGAQESKDEVEKTDIPYIISKGRKGGSNLAAAIVNAILYTM"
     gene            26689..27915
                     /locus_tag="KR294_001562"
     CDS             26689..27915
                     /locus_tag="KR294_001562"
                     /EC_number="2.1.1.195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-5B (C(1))-methyltransferase"
                     /protein_id="HBH0239644.1"
                     /translation="MEEYVYIDGKKYRRGYTTGSCATGASKAAVYMLITKNRINTINI
                     DTPKGIPLLLKVDNINISDTFVECSIKKDGGDDIDATHTMDIYARAEIVAKNDKNKGY
                     LTLKDIDSLSTNSECKSELYKFIRVYGGTGIGVVTKKGLSVDVGKPAINPTPLKMINH
                     EIRKLIGDNFESILGNDKVLKITIFAPQGETVAKKTFNPRLGIVGGISIIGTTGIVEP
                     MSDDGWKKSLSIELQMKKEQGLDKIILVPGNHGEQFIREKLNLDIKYVVRVSNFIGYM
                     IKEAQRIGYKKILMAGHIGKFIKVSAGIFNTHSKVADARSEILVANLALMGARYEFLN
                     KINQCVTTEEAVELINNSEYREVYNILSNKCRERVKQYLNEDSDDIDVEVIIFSMDKS
                     LLGKSDNTDDLVEVFI"
     gene            27912..28520
                     /locus_tag="KR294_001563"
     CDS             27912..28520
                     /locus_tag="KR294_001563"
                     /EC_number="2.1.1.289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-7 (C(5))-methyltransferase"
                     /protein_id="HBH0239645.1"
                     /translation="MINIIGLGPGNLDYITKKGENLISTSDVLIGGKRNLESIKNFEG
                     EKIVLDSNLREIIEYINNNKEKQISIIASGDPLIYGIGRYLSKNIDNKMLNMVSGISS
                     LQYIFSKIYVDMNDVYITSSHGKVPDFDYILSHKKVCMVTDSKIGPKQISREIIDRNL
                     NKIIVVGENLSYDNEKITIAKPEEIIRMDNFDMNVVVILDEE"
     gene            28510..29085
                     /locus_tag="KR294_001564"
     CDS             28510..29085
                     /locus_tag="KR294_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating cobalt-precorrin-6B
                     (C(15))-methyltransferase"
                     /protein_id="HBH0239646.1"
                     /translation="MRNSEFITGKVPITKEEVRAISISKLNLVNAKNLIDIGAGTGSV
                     SVEAAYNYPNLKVISIEKNDDAIELIEKNKKKFNLKNIEVIKGYAPINLGLNVKVESI
                     FLGGTGNNLEEIIEWSKKNLVTGGRLVANFIIIDTFNQTLKLLKKHGFKEIDVCVLNV
                     SKLEKLGKGEYFKPLNPIYIISCEKGENDDE"
     gene            29078..29830
                     /locus_tag="KR294_001565"
     CDS             29078..29830
                     /locus_tag="KR294_001565"
                     /EC_number="2.1.1.271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-4 methyltransferase"
                     /protein_id="HBH0239647.1"
                     /translation="MNKVHFVGAGPGDKELITLKGYKLLSNADVVIYAGSLVNPELLE
                     YCKEDCQIHNSAHMDLQEIIDVMREGIENNKSVVRLQTGDFSIYGSIREQVEDLNKLN
                     IDYDCTPGVSSFLGAASSLGVEYTVPEISQSVIITRMEGRTPVPEKESIQSYAKHQTS
                     MVIFLSVQEIEKVVSKLLEGGYPKDTPIAVIYKATWADEKIVKGTLSDIAVKVKENNI
                     NKTALIMVGRFLGEEYNNSKLYDKDFKHEYRG"
     gene            29814..30935
                     /gene="cbiG"
                     /locus_tag="KR294_001566"
     CDS             29814..30935
                     /gene="cbiG"
                     /locus_tag="KR294_001566"
                     /EC_number="3.7.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin 5A hydrolase"
                     /protein_id="HBH0239648.1"
                     /translation="MNIEGNIAIICITENGKKLALKINSLVNNCVIYHVKNKKSNLVV
                     EETCVHTVQKKLSDFVGEIFSKFDYIVFIMATGIVVRSIAPYIISKFSDPAILVMDEK
                     GKNVISLLSGHIGGANSLTQYISSLIDANPVITTATDINQKASLDMIAKKLNAHIDNF
                     RESVKEVNSMLVNNKCVGLYIDEGYQVDTRGFKLIESKDELRDSFSNTYIEKLVVVSN
                     KINCIEDIENLNLDNKFEHCYSTKKIIKVIPRDIVIGIGCRRNTDSELMYNSLEEFLN
                     KQNIDIRAINTVGSIELKKDEKAIIELSKILKVPFKTFSVDEISKVDNLFDKSDFVKK
                     NVGVYSVAEPVAYLLSKGNLLVEKHKYKGITFSVGRIKI"
     gene            30932..31657
                     /gene="cobJ"
                     /locus_tag="KR294_001567"
     CDS             30932..31657
                     /gene="cobJ"
                     /locus_tag="KR294_001567"
                     /EC_number="2.1.1.131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011701973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="precorrin-3B C(17)-methyltransferase"
                     /protein_id="HBH0239649.1"
                     /translation="MIYVVGIGPGSKDTMTLEAIKAIEDSEAIVGYKTYIKLIEEFIQ
                     DKEIIQNGMRQEVDRCKQAVEEAKKGKKVAVVSSGDAGIYGMAGLILELISKEDEDIK
                     VKVIPGVTASIGAAAILGAPIMHDFCHISLSDLMTPWEVIEKRLRLAAEADFVICLYN
                     PRSKGRSEHLSKAFKIMGEFKGGDTPVGVVKDVGREKEEKFVCTFENMDFEKVDMTTM
                     VIIGNKSTYINGELMITPRGYTV"
     gene            31654..32406
                     /gene="cobK"
                     /locus_tag="KR294_001568"
     CDS             31654..32406
                     /gene="cobK"
                     /locus_tag="KR294_001568"
                     /EC_number="1.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="precorrin-6A reductase"
                     /protein_id="HBH0239650.1"
                     /translation="MILILGGTSDSLSICDKINELKNQPYILSVTTDYGRELAQQHAE
                     NVILGKLGKEDMLKFIKDNNIVKIIDATHPYAVEVSKTAITCAKLLNIDYIRFERKSL
                     IEEIDYDNKFIVDTIEEACEIANKIGTNIFIGTGSKNLNRFIEEISDKNLVVRVLPTS
                     EVILSCEKLGLSADNIVAMKGPFSQYINEETYKHYNIDLVITKESGIAGGFLEKVNAC
                     KTFNIPVIIIKRESINYENVFNDINKIKDILV"
     gene            32425..33903
                     /locus_tag="KR294_001569"
     CDS             32425..33903
                     /locus_tag="KR294_001569"
                     /EC_number="2.1.1.151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-factor II C(20)-methyltransferase"
                     /protein_id="HBH0239651.1"
                     /translation="MKKALLVVSFGTSYHETREKTIDICEDKIKNSLKSHDFFRAYTS
                     NMIINKIKKRDGIEIDNPIQALDKIYEQGYDEVIIQTLHIICGEEFNKLKEQVDGYSS
                     KFKKIVLGRPLLTHIEDYQEAVEAIKHQIPHMESNEAVVFMGHGTLHESHSAYPALEY
                     MLRDNGINAYVGTVEGYPEIEHVIRRLKEGNIKTVNLMPFMLVAGDHAINDMAGDEED
                     SWKTILEENGFNVRVHLKGLGENSYIQDKFVRHAVKCAENAKFYGIGAGPGDGSLLTI
                     KAVNTLKKLDILYTPESKKGGDSLALSIVSEYLPESVEIKSRHFPMSFDGNEKSLAWD
                     NVAQEIISDVNDGKNVGFVTLGDPMIYSTYVYIMKRILGEVEVETIPGISSFSNIASN
                     QNFPLVMDKEALVVIPCTMEDDKIEYALQNYNSIVLMKVYKNFKEIIKKLEKYDLIEH
                     AILVSNSSQESENVFTDLKEAHLEDKISYFSTILVNKDNKIK"
     gene            33933..34838
                     /gene="hemC"
                     /locus_tag="KR294_001570"
     CDS             33933..34838
                     /gene="hemC"
                     /locus_tag="KR294_001570"
                     /EC_number="2.5.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylbilane synthase"
                     /protein_id="HBH0239652.1"
                     /translation="MNIVVGTRGSNLALIQTEWVINELKKKYPEISFEIKIIKTKGDL
                     IQNVSLDKIGDKGLFVKEIEQQLLDGKIDIAVHSMKDMPSYLADGLKFAHTPKREDPR
                     DVLILREGYKNLDDLPHGAVIGTGSKRRKFQLLKQRPDLNIVQVRGNVETRIRKIKDE
                     NMHGIVLAASGIIRANLQDKISSYLPVDVVIPAPAQGALAIEIRSNDSAIEGIVNSLK
                     DENTEIQILAERGFLDGVNGSCHIPMAAYCEIIQDKIHLTGLYGDSEGKKVVIKSIDG
                     DISSPRELGLKLAKLVLKEYENYEG"
     gene            34828..36327
                     /gene="cobA"
                     /locus_tag="KR294_001571"
     CDS             34828..36327
                     /gene="cobA"
                     /locus_tag="KR294_001571"
                     /EC_number="2.1.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen-III C-methyltransferase"
                     /protein_id="HBH0239653.1"
                     /translation="MKGKVYLVGAGPGDYKLMTLKGLECIRKSDVIVYDRLANSSYLR
                     EAKPDCELIYVGKASSNHILPQEDINRIIAEKAKEGKIVTRLKGGDPYVFGRGGEEAE
                     TLVDEGIEFEVVPGITSAIGGLCYAGIPITHRDHASSFHVITGHLKGDDSGELNWNAL
                     ANNKGTLVFLMGISNLEKISENLMKEGKDKDTPVALISWATRYNQRVVTSTLENVYET
                     AIKEEVKPPTLIVVGSVVGLREKLNFFESKPLFGKSIAVTRSRNQNSVLVEKIMDLGG
                     NPIEIPTIKVEKIQNNINLENEIKNINKYNYLILTSKNAVEIFFEKIYEMNFDLRILS
                     NLKVCAIGSATSNELKKRGIIADIVPKKFVAESLYEELAPILNDDDNILIPRAENARD
                     YLVDKLKAICEVTEVHIYRTVIDEEKKGEILDILNSNDIDYITFTSSSTVNNLVEIIG
                     KENIKILEKIKTLSIGPITTETINSLGIKLYKESATSTIDSLVDLIIKN"
     gene            36344..37309
                     /gene="hemB"
                     /locus_tag="KR294_001572"
     CDS             36344..37309
                     /gene="hemB"
                     /locus_tag="KR294_001572"
                     /EC_number="4.2.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porphobilinogen synthase"
                     /protein_id="HBH0239654.1"
                     /translation="MLRRPRRLRASKAIRNLVRETKVNVEDLIYPLFVVEGENIKEEI
                     KSLPDVYHLSIDMLEDEIKEISELGIEHIMLFGVPDEKDECASQAFNDNGIVQKAIRK
                     VKEINSDINVITDVCMCQYTSHGHCGILTDTGYVDNDKSLEYLAKISVSHAKAGADMV
                     APSDMMDGRIQAIREALDENGLENVGIMAYSVKYASNYYGPFREAAHSAPSFGDRKTY
                     QMDPANSNEAIIETELDILEGADILMVKPALSYLDIIRRVKDNFDLPLAAYNVSGEYS
                     MLKFAVKEGLLNEDVILESITSIKRAGADIIITYFAKDIAKLLKK"
     gene            37462..38040
                     /locus_tag="KR294_001573"
     CDS             37462..38040
                     /locus_tag="KR294_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional precorrin-2
                     dehydrogenase/sirohydrochlorin ferrochelatase"
                     /protein_id="HBH0239655.1"
                     /translation="MLYPINLKLDELDVVIIGGGEVAYRKCKNFLEFNKNVTIVSKQI
                     LNKFYDLKGNIKIIKDDYKEIYIKDASVIIAATNNRELNMEIGLYCKAKNKLVNVVDN
                     IEISNFTVPSYIKRGDLLISVSTGGKSPSLSSKIKKEIEERYTEDYEEYLNVLGDIRK
                     KVIKKYEDKSKRKDVLNMLVTLDLEELKKFDI"
BASE COUNT        15167 a         4014 c         6753 g        12154 t
ORIGIN      
        1 aacaaaatga ttttagtcta tctattagat attcttcgct ctcaatgctt agaactttta
       61 gatatataca ataagtgctt tcatttgtaa aaatttctat agtattatct tgtttattta
      121 cacctacaat atctttaaaa ttgatatgat ttttagtatt tttacatttg aaaatatatc
      181 tgttatcaat taaaatctca tcattagtaa ttgaaatata gggtttatct catgctttat
      241 taaaaattta tatgtttgtt caagataaaa acttacaaat aataatagaa aagttacttt
      301 aaatgtacat attatcgaaa atattatcac aaaaatactt ataatatata tttgtttaaa
      361 ataacctcta tcgcaatagt ttattaacga tatggaaata aaagtgttaa atcagatttt
      421 ggagaaataa ctttaaatat ttccagactc tttttagaca gcctccataa ccttatattg
      481 aacctattta ttaactttgt acttacatat accacttata taagtttcgt atatattaaa
      541 gtccttatct gttactataa aatctgcctc cataccttga tgtatggagc cacaaacatt
      601 atcaatatta caacttaaag cagggatata tgtagccatt tttattgcat cttctaaagt
      661 ggctatgttc caatcaacta tatttctcac agccttgtcc atagttaata cacttccagc
      721 taaactccca ctatttaatc ttgcaacact attttttaca tttacattaa acttaccaag
      781 agtatatttt ccatcctcca tagcaccagc tctcatacaa tctgtaatta aagctatgtt
      841 attactagac ttagcatcca tcattatttt aacagctatt gggcttacat gatgaccatc
      901 acaaattaat tcagcataag tatcttttag taccatagca gccccaacca ttccaggttc
      961 tctatgattt aaaggactca tcccattata tgtatgtaca aacactttag cacctgaatt
     1021 aacgacttgt ttaacttgct caaatgtagc tgaactatga ccaagagaaa ctgatatatt
     1081 atttttagtt gcatatcttg ttaattctat tgaaccttta cgttctggag caattgctat
     1141 ttttcttatt aaatttttcg attttttttg ccataatttt aatatattga tgtcagggtc
     1201 tttaaaatat ttttcatttt gagcgccctt atatttttct gtaaaaaatg gaccttctaa
     1261 ataaatccct tgtatttttg caccctcaac tcgattgaag ctattgctta tattttctac
     1321 agaatcactt agtgtatcta cagaatcagt taaagttgta ggtaggaaag atgttactcc
     1381 atattttaat aagccttttg aaattgtgtt tattgcttca aatgtattgt ccatgacatc
     1441 tgcacctaaa agaccgtgaa tgtgagtatc aactaagcca ggagcaatat atttacctga
     1501 aaaatctata acattatcag taacattagg tctttcttgt tgaaattcac cgaatttgcc
     1561 attaattata ctaaggtaac ctttttcttt gattccatgt ttcataaaaa atttatctgc
     1621 ataaataaaa cttttcaaaa taacctcctt ataattatat tatcattgtg gcattgacgc
     1681 ttataatatc attctgtttt cttgaaagtt atttaactta ctatcttaca tgtcttactc
     1741 tatatacaaa tttatcactt ctagcgacac tcaaagtaaa ttcaataact atattgtcat
     1801 cattatatgt ggtacgaagt aatttcagac aaggtgaatc tcctggtact tccaataact
     1861 tagcttcctt atccgagatt attccagctg aaaattcttc atcagcaact ttaataatct
     1921 cgccataatc ttctctaaat atttcatata aaggtttttg ttcgattttt tcttttgtca
     1981 atcctataaa ttctttcata ggaagatatg ttctttcaag catcatagga aggtcatcag
     2041 caagtcttaa acgcattatt tttatcattt tttcaccagg agttatacct aatttttcag
     2101 agaaatactt tgtactttct actacctcaa atgataatac ctttgtacct ggcttttttc
     2161 cttgtgttct catataatct gtaaaactat aactttccat taagttttga gaattttgac
     2221 ttagtgcagc aacaaaagtt ccttttccat gtcttttgta tatatatccc atatgctcta
     2281 actcagccat agctagtcta actgtggttc tacttactcc atattcatca caaatttttc
     2341 tttcggaaag cattctatcg tttggttcca tctcattttc aatcttagtt cttaatatct
     2401 caacaagctg gtcatatatt ggtcttttat catttctttt tatcataaaa atatagtcct
     2461 ttctaagtgg ttattaccac aatttgatta tagaatatag aattatttat gtcaatgaat
     2521 aaagtttaat caaaattcaa taagtaaggc tattaattta ttataaaatt atggtacatt
     2581 gacaaaacaa gtaaaataat ttatattcaa attggtaata accactttgg atatattata
     2641 tgaggtattt tttattttac agattaattt attgtttaga aaagtaaaaa ttaataatga
     2701 ggagaatcta gtatgattac agtaataaca ttcaacccat ctatagatag aatgtataga
     2761 gtgaataata taaacatagg tgaggtgcaa agggtagtaa gtaagaatgc aactgctgga
     2821 ggtaaaggat taaacgtatc taaggtatgt aaaattttaa aagaaaatcc tttagctatg
     2881 ggatttctag gcggatttaa tggagaattt ataaaaaatg aacttagaaa actagatata
     2941 caaaataaat ttacaaaaat agagcaggaa actagaaatt gcttaaacat aattgaggac
     3001 aataaagtta gtacagaatt tttagaaaaa ggaccaatag tagaaaaaag cgatttagag
     3061 agatttgaaa atgatataga ggaagtacta aaaaatacta aaatactggt agcttctggt
     3121 agttattgtg agaatatgcc gatagactat tatgaaaaga taggaaatat atgtagagca
     3181 aataatataa agtttatatt agatacatca ggagaagcat taaaaatagc tttaaaatca
     3241 aaaccatatt taataaagcc aaatatagat gaaataagac atttattagg aataaatata
     3301 gaatcaagag aggaaattat cttgtcagga aaaaaactta ttgaaatggg tgcagagaat
     3361 gtatgtatat ctttaggaaa agatggtatg gtgtatttaa acgaagataa cgtatattat
     3421 gtaaaagtac cagttgtaaa gtgtataaat actgtaggta gtggagatag cacagtggct
     3481 ggatttagtg taggtatttt aaggggttat aaaatagaaa atttacttaa atttgcaaat
     3541 gcttgtggta taagtaatgc tttaaatatg gaaactggat ttgtagattt gggagaaatt
     3601 gataaatatc aagatttagt tgaagtaaaa aagttaagtt aaatacattt aatgggaata
     3661 taataaattt aatgttgttg taatagattt taattttaat ataaaagata tagtcttata
     3721 taaaaatagg ttagaaaaat tcatttttaa cctattttta taataaatat ctattttact
     3781 gaatttataa ttttctctag taatctttga gccttgatac actcttctcc actgatagct
     3841 ggttttatat tattttctat acaatcaata aaatgatttg atatatcctc aaaacccttt
     3901 tgttttaata tatttaccca tgcaccactt tgctttaaag ttaggtttcc accttcttct
     3961 atttccagta cattaagatt cttaactctt tgaatcttac cctttgaaag aatttcaact
     4021 tgttctaact ttgttccaga atctctatgc atagaggtgt ttatagagaa atttttacct
     4081 ttaagtttat gacttacaaa tataagattc ttattgtctg ttaaaaataa atcctctcca
     4141 ctaatttcaa catcttcatt tgctaaccat aaagcagtgt caataacatg tatatagtca
     4201 tctataagag tactgtcgaa tttaacattt cttaaggaat ttaatccatg tttacatata
     4261 ttgatagata caatttctgt agcattattt ttaatttctt tgtacatagg acagaatcta
     4321 cggttgaatc caaccattaa atttaagttt tttttcgtac ttaattcgat aagttcttct
     4381 ccttgactta ctgttgaagc aagaggtttg tctacatata catgaacacc taaatttaat
     4441 aatattttta taatttcgta gtgtgtttct gtagagctat gtagaaaaat acaatcacat
     4501 tttttagcta gggattcaat agaatcgaat tgcatgattc tataatcact acagactttt
     4561 tcccttttaa ctttatttgg agtaaaagct cctacaaact caaatctctc agacttagtt
     4621 aatataggta aatatgcctt ttgagctatg gagccaagac ctatcattcc catttttata
     4681 tttttcataa tactttctcc taaggttttt atatttacag aattgattat aattcagaca
     4741 cataaatttg taaactttgt atcaaaaaat aaatttaaag cttatataag taaattagcg
     4801 aaataagaaa tattgataaa gtaattttgt aggatatcta taaaattgat tgatataaat
     4861 attttatgta ttgacaaaaa attcaaatta atttatattt ggattagtgg taattaccac
     4921 tttggtctga acaagttttt atcgtaaaat aaaaatacta aagtatatag agtatgattt
     4981 tattaaattt ttaaagataa actataaaat taattaaaat ctatagtgta tattttatag
     5041 tgagtttaag tagtactaaa aatctaagca aaaaattata aaagagtata tttttttata
     5101 gtttaaagtg gttataacct cattaccaaa tgtaaacgtt acaagtatga aaggagaatg
     5161 aaaatgttta aattagaaga acaaaaacta aaagatttag gtgcaataat aacaactaat
     5221 gaaataaaac aacagcctga attatggtta gagacttatg aaatatataa atctaacaaa
     5281 gaaaaattaa gtagattcat agatacaata agtaataatc atgggcagtt tagagttata
     5341 tttacaggtg ctggaacttc agcttacata ggaaattcaa tacttcctta ccttaaaaat
     5401 aaaaatgaca taagaaaata catatttgaa gcaataccta ctacggatat agtttcaaac
     5461 ccatatgatt acttaaaaaa agatatacca acattattaa tttcatttgc aagaagtgga
     5521 aatagtcctg aaagtttggc tgctttaaat ttagggaata agattgtaga taatttttat
     5581 catttagcta taacttgtaa tccagaagga gaactagcta agatgactaa aaacgacgaa
     5641 aataattact tgttattaat gccatcaaaa tcaaatgatg aaggctttgc catgacagga
     5701 agtttttcgt gtatgatgtt atctgctatg ttaatattcg atagtttaga agatgatgta
     5761 gaaaagtcat atataaatgc aatagttgaa atgggaagaa atgttataga tagaaaagat
     5821 gaaatacatg agttaataaa taaagatttt gatagagttg tatatttagg ttcaggagga
     5881 ttaggtggtt tgacacaaga agcacaacta aaacttttag aacttacagc aggaaaaata
     5941 tctacagtgt atgattctcc tatggggttt agacacggac caaaatcatt tattgatgaa
     6001 aatacacttg tatttgaatt tgtatctaac tgtttatata caagaaaata tgatttagat
     6061 gttttagagg agataaaaag ggataaaatt gctaaattca cttgtgcagt gtcagtagaa
     6121 aatgaaaata acttctcagg aacaaagttt gagtttaaag aaaagtataa taaattacca
     6181 gatgtgtatc ttgcaatgcc atacatattg tttgcacaaa ctatagcatt gtttgtatcg
     6241 gtaaaggttg gaaataagcc agatacgcca tcagctacag gaacagtaaa tcgagtagta
     6301 aaaggtgtaa caatatatga atattaaaag ataagattaa aatattataa ctaaataatt
     6361 tgggagggta tcaatgtggc attagtaaca acaacatcaa tgcttaaaaa ggcacaagat
     6421 gaagggtatg cagtaggagc atttaatgta gaaaatatgg aaatggtaat tgctgttata
     6481 gaagctgctg aggagttaaa ttctccagta atattacaaa ctactccatc tactgtaaaa
     6541 tatgcaggtc ttgattatta tctagcaaat gcaaaggttg ctgcagaaag agtaaagata
     6601 cctgtagcaa tgcatctgga ccatggttca agttttgacc ttgcaatgaa agctttaaga
     6661 agtggatata catcaataat gatagatggt tctcatgaaa gctttgaaaa taatatatct
     6721 atatctaaat cagtagtaaa agcatgtagt ccttctctta taccagtgga agcagaactt
     6781 gggaaagttg gtggaaaaga agatgattta gatggcggga atagtaatga ttatacaaat
     6841 ccaaaagagg caaaagagtt tgtcgataga acaggaatat cttcattggc tattgctata
     6901 ggtactgcac atggattgta taagggtgaa cctaaaatag atttagatag gttatcagaa
     6961 attaaaaatg tagtttcaat acctttagta ttgcatggag gttcaggaat acatgatgat
     7021 attataaaag aagctataaa aagaggtatt gcaaaagtta actatgcaac tgaattaaga
     7081 attgcatata gtaaaggggt taaaaaagtt ttagatgaag attctgaggt tatagaccct
     7141 aaaaagtatg gattagcagg gcttcaatca gtaaaggatt ttgtgaaaga aaagattaaa
     7201 gtgtgtgggt ctgtaaatag agtataaaaa taaaatatcc taaatttatt ttagataagt
     7261 ttaggatatt tgttatatga aaaatttata ttaattatat gtaaatggtg tatttttttc
     7321 atttaattga tgaaaaatat cagcttttat tggtaaagta ttacatatat aattaaaata
     7381 tactaaaaat tgaactatat attttattat tataaaatat ttatattaaa ttgtggaatt
     7441 aaaatatact aggatataaa attcttaaat aaaaagaaaa gattgttttt ataaaaaata
     7501 ttttttatac cacttaaaaa aacacaataa taacactgag ggaggtgggg atatgagaga
     7561 acgcattatt cttgaaacat taaaaaatag tagtggttat ctaaacatag attattttgc
     7621 agataagttg ggggtatcta ctcgaactat cagaaatgaa ataaaaaaga tagaaactat
     7681 aaaagaatgt aatggtttta aattagaata taagtctaaa ttaggatata ttctaaatat
     7741 taaagaccaa gataaattcg agcattatct aagaaactta ccctcagatt tagttgaaaa
     7801 tccagaacaa cggttagagt ctataatagt agaactttta gtaaatgaag gttataaaac
     7861 tatagaacag ttaagtaaaa aatttctagt aagttcatcc caaataaaaa atgatttaaa
     7921 aaagatagat gaaaagataa aggatacaga attaaaacta gagcgaaagg ctcattatgg
     7981 aattaaaata gaaggttcta taaaagaaat tcaaagtata ttggtggata gttattttag
     8041 agggaataga aatataacag agtacaggaa taagtttata gataatttaa aattagctaa
     8101 tattagaagt acaataaaaa atgtacttaa tgaacatgat ttagaagcaa atttaacaga
     8161 acttgaggaa atattagcac aaattattat attgtatata agagttagta tgagagtagc
     8221 gggaaatgct agcgatttaa aattatatac agaagattta attatagata aattattaga
     8281 taaaattttt agagataaaa aatataacct taattatgat gaaaagtatt atttaaagga
     8341 gcttataaaa ctaaagacta aagataagaa agccactata aagaatattg ataagaataa
     8401 acttcaagat attatgttcg aattttttag agagatagat aaaaaatata actctaattt
     8461 tttagaagat aaagagttct ttaacttatt ttacttacat attgcatgtt taatagaacg
     8521 tataaagaag aaccacaaga taataaatcc tttttcagtt aaaataagtc aacagtatcc
     8581 aactgttttt aatttatcta ttcaattttc aaaaatcata gaaaatgagt atcatataaa
     8641 aataagtcaa gatgaaatag ggtttatagc tactcacatt gctgttcctt ttgaaaagag
     8701 agaagaagct aattttaata aaaaatataa aatagcaata atatgctctt ctggtggagg
     8761 tagtgcattt ttgataaatt taagacttaa agaaattttt ccaaatgctg agataagaaa
     8821 tttttcatta ctagaagaaa aagctgtaat agaatttgca ccagatttga ttttttcaat
     8881 aacaaatctt ttatttgaaa taaatgctcc agttatactt ataaatgaaa ttttagacga
     8941 attggattat ttagatatta aagaaagtgt tagatttgca gaccatatag gaaatatatc
     9001 aagcccaaaa caatatatat taggtctatt tgataagaat cactttaggt gtataaaaga
     9061 taaagctaag tataaggata tccttgatag tatgtcaaaa tgtatagttg acgagggcgc
     9121 ttgttctcca acctatccca aagatgtatg ggaaagagaa agctatttga gtactattta
     9181 tacaaatggg gtggctatac ctcatccaat cgagatgaca ggaaacaaaa atataatatc
     9241 agtagctttg atacaaactg atattattta tgaaaatagg gtgcctaaaa ttattttcat
     9301 gatttcatta ataaagggaa atttagaact tcataagcaa atatctaaat atttaagtaa
     9361 gattatggca aataaggata tggtagacat gctaaataag tcacaatctt atgaagagtt
     9421 tatgtataag ttaaaaatct atctgggagg ttagacatga atatagagtt ttttaagagg
     9481 ttgtcagaag cagatggtat agcatctaat gaagaagagg ttagacatgt tttattggaa
     9541 gaactaaaag cttatagtga taaaattatc tgtgatgggc tagggagtat catcttttct
     9601 aaaataaaag atgagagtgc accaaacgta atgatttgtg ctcatatgga tgaagttgga
     9661 tttatggtga gaagtataga caaacttggt atgattcact taataacaat aggaggagta
     9721 aaacctcttg cacagtttgt acaaaaagtt agaattacaa caaaagaagg gaagaaaatc
     9781 cctgctgtca taaatgctac atataataat ggtaaggctg aaaatatata tgcagatatt
     9841 ggagcatata cagaagaaga tgtatataac ctagggatta atgttgggga tatggtaaca
     9901 tatacaacaa gctttgagga atttacttta ccagaccgat tagtgggaaa ggcttttgat
     9961 gataggatag gatgttttgt gatgggagaa gttttaaaag aacttaggaa agaaaatcta
    10021 aattgtaata ttcactttgc ggctacaagt agtgaagagg ttggaataag gggagcaaag
    10081 acatcaacac agttaataaa tccagatata gtatttgtaa tagatgtagc atgtgctaaa
    10141 aatgagtttg tgagagacta tacaaatcag aaacaaattg ataaaggtgt aatgctaatg
    10201 catagagata ggactctagt ccctagtaga aaaatgatag attatgtaat ggaaattgct
    10261 gataaaaata atataccact tcaacatgat atgtttgaat caggtgggac tgatggagga
    10321 gaagcacatc tcgtaaatga agggaaacct tgtgtagtaa cttgtgtacc agttagatat
    10381 ggtcattgtg cattttcaat agtaagtaat aaagatttag agaacattat aagattgtat
    10441 acacagttaa ttttaaattt tgatgaagaa caatataaac atataagaaa ttttatctaa
    10501 aggagaataa gaaaatgtca acagaagtac aaataatgga acttatatca actgcaggag
    10561 agagtaaatc gaaagctttt gaggctttaa aaaaagtgaa gtcaaaagat tttaaaggag
    10621 caaaattgtt aatagaggag gctcgtaaaa tagatattga agctcacagg atacaaacag
    10681 aattaataac tcaagattta aatgaagatg ttgaaagtcc agcaatgagt cttttaatgg
    10741 tacatgctca agaccactat atgacttctc agctagcaaa agacttgata gaggctttga
    10801 tatattgtct tgataagtaa ttgtaatata gaaatagatt atttatgtaa aaattctttt
    10861 aaaagtttag atgcttttaa gagataataa aaatacaaac tttaggagga attattatga
    10921 aaatattatt atgttgtgca ggtggatttt ctactaatat gttaatgcaa aatatgaaaa
    10981 aggtggtaaa agagagtgct aaactcaatg aaaaagattt tgagtttaca gctataccag
    11041 cagattcaat agaaagtgaa gttgatgatt gggatatagt acttataggt cctcaaatag
    11101 ctcacaaaat agacttctta aaaggaatat tagagccaaa aaataagcct tttgcagtaa
    11161 tagataaaga tgtatatgga aaaatggatg gagctacagt tatgaagttg gcattaataa
    11221 cttataagaa acatcaatta gctcaaggat aataaaaata atgagggaaa agggagatta
    11281 gatatgtttt caaaatttga agcatttatg aatagagtat ttatgccttt agctcataag
    11341 gttgacaatc aacgtcacct tggttctata aaggctggta tggttgctat gacaccattc
    11401 acaatattag gaagtatatt tgcaatactt ccagcacttc caaatatgct tggagaaaat
    11461 aatccaataa gcaaattcat acttaacaat tcagcaatat tggatttacc agtaagtctt
    11521 tccataggtt taataggatt atatgcttgt atgtgtattg cttttaatct ggggaactac
    11581 tataaattat atataccagg ttgtgttgca ctatcaactt tttctttttt attcctagta
    11641 gcatcattta caccagatgg agctttagaa ataggaaatt taggagctaa agggctattt
    11701 acaggtatga tagcagggct tggttctgtg gagttatata atttttgtaa taagaagaat
    11761 atcacaataa aaatgccaga aaatgtacct gattttgtat ctaggtcttt tgaattaata
    11821 cctactacta taatagtttg tggaactttt atagttgctc gttttatttc attaaaagta
    11881 tttggagaat tacctccaca gatacttact caatttttat ctccattagt aggaagtatg
    11941 gataacccat ggtcagttct tgcacttaac tttgctatat gtactatatt cttttttgga
    12001 atacattcat cagtatttag tcctataact agacctataa tgattacatt tatagctgaa
    12061 aacatagcag ctatgcaagc tggagaaaca atacctcatt tctttacagc aggagcttca
    12121 agtgcattct ttggatttac aggatgtgga attagtatag gttgtgtaat tgcatgtatg
    12181 ttatcaaaaa atgcttccta taagaagatt ggacgtgtat cattattccc tgcattattt
    12241 gggataaatg aaccaatatt atttggagca ccgataatat taaatccaat aatgtttata
    12301 ccacatgtat ttggtggagc tataataggt acactaccaa tgttttttat gcactgggga
    12361 tggttagcaa agccagtatt tgaccctcca tatgtagggg tattcttaga aggattttta
    12421 actaatggag attggcattc tatattagca aatgcattgc aattagtatt agcagtttta
    12481 ttatattggc cattctttaa aataatggaa cgtcaacaaa ataataaaaa acaaaaagaa
    12541 gaaactaaga atatattctc taaagaagaa gaagacttat tggatgattt aggattggat
    12601 ttctaatatt ttgttatgaa taatacaatg gagagattag tatccttaat ctataaaaga
    12661 ggtgttgacg ctcttttgat taaagcaaaa aatactaaaa gatatatagg agctttatca
    12721 ggtagtggtg tatatgtgct tgttactaag gataaaaatt atcaaattct agatggcaga
    12781 tatattgatg aagcagataa aaaaacgact ggtttcataa aaaggattgt atctcaaggt
    12841 tcttatatac caactataat tgagttatta aaagaattaa atataaaaaa gttagcaata
    12901 gaaaaccaag ctatgagtat acaagagtat ctttcactaa aaaatgaagg ttttgaaatc
    12961 aatttaataa caaatgaatt atggaagcta agggctataa aatctaaaga agaaattgaa
    13021 cttattaaaa aggcttgtga aattacagat gaagtatttg atgaggttat ttctgaaatt
    13081 aaaaaagata tgactgagct agaagtatca gctctaattc agtatcatgc attaaaaaaa
    13141 ggtgcaagtg gaatgtcttt tgaaacaata gtggtatcag gagaaagagg tgcaatgcca
    13201 catggaagac ctacaaacaa aaaattgaaa gtgaatgaag ctataacaat agattttggt
    13261 gttgtttatc aagggtatca atcagacatg actcgtacaa tatctatagg taaacctcct
    13321 aaaattatta aagagatata tgatgtagta ttggaagcac aattatctgc aatagagtca
    13381 ataaaggaag gaactagggc aagtgatgtt gacaaagtgg ctagaaaaat tatagataaa
    13441 catggatttg gcgaatattt taatcatgga ctgggtcatg gtataggtct tggagatggt
    13501 gaagtcccca ctttaaatcc aaatagtgaa gatatattag tggaaggaat ggtaatgtct
    13561 tgtgagccag gtatttatat tccaaatgta gggggagtta gaatagaaga tgacattgtt
    13621 ataatagatg gaaaaggtgt tccactcaat aagacatcca aagagtttat aatattagga
    13681 gagtaaaatt atgaaatata attttaataa agtattaaat cgtaaagaag gaaattgtag
    13741 aaaatggagc aaccatgtga ttaaagaaaa attcggctta aatgaagatg caattcctat
    13801 ggatttagct gatatcgatt ttgagtgtgc tcctgctata aaagaatcta tcttaaaaag
    13861 agcatcagta ggagattata gttatacttt tataggagat gacttctatg atgcgattat
    13921 aaattggaat aaaagaagat ttgatgtata tatagaaaag gattggataa aattaacttt
    13981 tggtactgtt tcaacccttc attatatagt ccaagcatat actaaagaag gagagggtgt
    14041 attgataaat acacctgctt atgacccttt tgcagaggct gtagtaaata ataatagaaa
    14101 gttgtgttgt agctcattaa aattagataa caatagatat tatttagatt tagaggatat
    14161 ggaaaatcaa atgaaatacg agaatataag attgcttata ttctgtagtc cacaaaatcc
    14221 atcaggtcgt atatggacaa aagaagaact atatcaagtg tcagagttat gtttaaagta
    14281 taatgtaatt ttggtaagtg atgaaattca tagagatata atatttaaag attatagatt
    14341 tgtatcttta tggaatgctc atccagaaat ttataaaaat agtataatct gtgtatctcc
    14401 taataaaggc ttcaacttag gtggattaaa aacatcatat gtattaataa gagatgtaaa
    14461 aattagggag actttattag aaagactaaa aagtaattca ataacttctc caaatgtatt
    14521 tgcaatacca gcaatagttg cagcatataa tgaaagcgaa gaatggctag atgctatgac
    14581 tagttatgta gaggagaatt ttgaaatagt ttatgatttc tttgaaacta atataccaaa
    14641 agctaaagtg atgaagtcag actcttcttt tttagcctgg atagatgtaa gagaagtatt
    14701 tagaaatgaa gaagaatcta aagaattttt tagacatgca aacttaacta tggtagttgg
    14761 aagttatttt gtgaaagatg gagatggatt tattcgtatt aatgtggggt gtcctagaga
    14821 aacattaaat gaggctctaa atagaatcaa aaaaacgtat ataagtatgt attgttaaat
    14881 cataaaaaaa gtatctatgg tttatataaa aacacattat ttagttatca aatattactg
    14941 gaattttgta ttccagtaat attttttgat taaggaatat tattgaggaa tattaaataa
    15001 tattatttca tacccttata ttaacttata taaaaatatt ttattatttt gggaacgggt
    15061 tagctaacct ttatctagtg tatatttata ttgtaagaag cagtaaaaac ttttccttta
    15121 ctaagtttat taataaactt cttatcttta taaattttgt tagaatttat actatcagca
    15181 agaccatacc aaggttctat acataaaaaa ggagcagtag aattagtttc actataataa
    15241 ggagtccaaa taccaactag agggaaatct tccatagata tagttacata tttactacca
    15301 tcattattac atatagatac ttcatctatg ttggtgtata tcaaagcatc attcttgaat
    15361 acttctggat ttaactgtaa gttttttaat tttccaatag gtattatatc atctgtaaaa
    15421 gaaccattta aattgatttt ttctacatca tttttacttt taaactcaag gtagtgttta
    15481 gaaaaatcat tttgttcgta aaaaggaagg ttgaatgcag gatgtccacc tatagaaaag
    15541 aatatatctt tagaatcagt attttttaca atccattcta cctcaatact attatcattt
    15601 aatgtatagt ttatgattag ctcaaaagaa tatggatact tctttaaagt agattcatta
    15661 tctgttaatt tataagttac aaatgtatct cctttatcta caatctcaaa gtccatatct
    15721 ctagcaaacc catgttgagt catgctatat aaattttctt ctattattgt ttcattatca
    15781 aaaagtttac ctactatagg gaacaatata ggtgattgtc taccccaata ttttttatta
    15841 ccatcccaaa gaatgttttt gtcgtatttt ttagaaaata ttttagttag ttcagcacca
    15901 aaactgcttg attcgataat taaattttca ttttgtaata tattcattta aaatctcctt
    15961 tattatattt tatgagtata ttatactata aagtataaag attattaaat tttatttgat
    16021 attatatttg aaaggtagat tttagtatat tttgaaaatt ttgttttgaa aatttgggat
    16081 tatttaagaa attttgtatt ataaatagaa ggaaatagat aaattgtata gaataaaata
    16141 tattaagata agttaataat gttaaatggg aagtgagttt atggaaaaac caaatacaaa
    16201 agttgttaac tttcaagagt ataaagacag aaaaaaccaa agagaagtaa atagagacga
    16261 acttttaaag cttataaaaa aaattgtgac ttcaaaatag ggagttgtta aactccctat
    16321 tttaatgggt ttcataataa ttaagacatt ctgagtccat ctatataatc tttgaattgt
    16381 gagaaatctg attcactact taattctatg gtttctgaac cttccgtata aaaattctta
    16441 agatagatag tataattatt atcaacacaa tcatgataaa tacatctata tccatcttca
    16501 tacaaacttt ttaacttaga aaaatcatcc acaatatcat ctccttaaag ttcttttaaa
    16561 tatattttta caaaaagcat ctaattgtat gcaaattgac aatgtaaaat aaaggaaatg
    16621 aacataaaat gtagaataat ttttatatgt atgtaaaaat aaaaagaaaa agttgaaatt
    16681 tttagaaaat aagagtattt tttatctaaa aagagagttt aaaaaataaa aaaatgttgg
    16741 gaggataaaa aatgagttta ttagaaagta tatcaaaaaa catatattcc ctagataact
    16801 cttctattga aaaaacaaag cagagattgg ataggcttat acatccaact ggaagcttag
    16861 gaaagataga agatatttgc atgcaattag caggaatatt tggcaatgaa aattttgaca
    16921 caagtaaaaa ggttataatt gcttttgcgg gagaccatgg tgtatatgaa gaaggcgtag
    16981 cacctgaccc tcaaaatata acaaaattac agtttccaaa tttttcgaaa ggtctatgtg
    17041 gagttggagt aataagtaaa tttgtagggg cagatgttgt agctgtagat gtaggaataa
    17101 actgtgatga aaaactggat ggggtattag actacaagat aagaaaaggg acatcaaata
    17161 tggcaaaagg tccagctatg agtaaacaag aagcaattag atgtttagag ataggtattg
    17221 aaatagcaga gcagtgtata gaaaaagatt ataaggttat tggtattggg gagatgggta
    17281 tagcaaatac tactccaagt acagcaataa tatctgtaat ttcagggtgt gacccgttag
    17341 aagttactgg tataggtgca ggtcttaaga aagaaagact aaagcataag gctgaagtaa
    17401 ttagaaaggc tattgaaatt aataatccaa atccaactga tggagtagat attttatcta
    17461 aagtaggagg gtttgaaata ggctcaatgg caggtgttat attaggttgt agtgctaata
    17521 ggattccagt agtaattgat gggtttattt cttatgcagc agcattaatt gcatataaga
    17581 taaatccaaa aactagagaa tatatgatag catctcattt atcagcagaa tcaggaacta
    17641 aaagagcatt agacatatta aaattagacc ctctattaaa tatggatatg agattaggtg
    17701 agggaagtgg agctgcttta gcatttgata taatagaagc ttcaaactat acttataaaa
    17761 atatggcaac ttttgatgaa attgacatgg gaagataaat ataaaaattt aatatgtagg
    17821 agtgttttga tgagtaaaat tattctagta acaggaggag ctaggtcagg gaagagtaac
    17881 tttgcagaaa aactatgttt tgacagaaat aataatacag cttatatagc aacctctatt
    17941 ccatttgatg atgaaatgaa agatagagta aaaaaacatc aagagaatag acctagaaac
    18001 tggaatactt atgaaatata tgaagatata tattccataa ttaaggagat atataaagaa
    18061 catgaaactg ttatactaga ttgtgtaaca ttattagtaa ataatctaat gtttgaacac
    18121 aatctaaata tagaagaatc tagtcaagaa gaaataaaca aattagaaca atacataaaa
    18181 gaacaagttg tcaaacttat tgaagaaata gaaaaaacaa atctatactt tgtatttgta
    18241 acgaatgagt taggtatggg aattgttcct gggaataaac ttagtagaat ttatgctgat
    18301 attgtaggtc gtataaatca atatatagct tcgaaaagta atgaagttta ttttgtagtt
    18361 agtggcatag ctatgaagat aaaggagtag tatgcaatta tgaaaagatt tattttaata
    18421 ctacagtttt tgacaaggat acctataaaa ttaaatgtag gatttgatga tgaattttat
    18481 aagtcaatag tatattttcc acttgtaggt tttgtcatag gtatattatc ctatttaata
    18541 ggatggattt ctatgctttt atttgaacca tttatagctt ctataataat aactctagct
    18601 ggtgtcttaa ttactggagg acttcatata gatggattag gagatacatt tgatgcaata
    18661 tatagttata gggataaaga aaagatgctt gaaataatga aagattcaag attaggtaca
    18721 aattcacttc tagcaattat gtttgtactt ttattaaagg ttggattcgt ttacgatata
    18781 ataagtaata attcattgtg ggttataatt tttatgccaa tgattgcaag gttaggagta
    18841 atgttattga catataaaac tgtgacacca agagaaaaag gaatgggaaa tttatttata
    18901 ggaaaattaa ctacaagtat gttaataact gctataatat acacattatt gatagttgct
    18961 cttattacta aatttatatt tttattacct aatatagtgt tgattaaagt attaggttcg
    19021 attatagtgg tttttgtatt tataatatta ttcaaaaaac atatttataa aaaaattgac
    19081 ggagtaacag gagatatatt aggctgtgga atagaacttt cagagcttgt atatttaatt
    19141 tacatatatt tgttaatttt tatgtttttt taaagtaaaa agtggtgata atatgataag
    19201 attaatatta ataagacatg cactgacaaa tgataataaa aaaggaagat tatcaggcca
    19261 tataaatagt tgtattagtg aagagggcaa actacaaata aataaaatta ccagatatct
    19321 gagtaatgaa aacatagata aggtttatac aacaccatct acacgtacta aagatacagt
    19381 agaaaaaata tcaaaattga aattattaga aatagaagaa aaagaagctt taagagaaat
    19441 tagttttgga gactttgaag gaagaacttt tgaagaaatt aaaatcaaat atccaaatga
    19501 gtttgaaaaa atgataaaag aaggtaacaa ctatagatat ccaaatggag aaagtttgat
    19561 agactcttat aaaagagtgg caaaagaaat tgataatata attttagaaa atgatagtaa
    19621 tttagataca aagacaatac ttatatgttc tcatgcagga acaataagaa atataataac
    19681 acatttgatt tctggtagtt ataagtatca ctggaacttt aaaattgata atgcatctat
    19741 tacagtttta gaaattgatg gtggatttgc tgtaatagat aaaatgaatt ttacagactt
    19801 catataattt aatcaaaacc aaacattaca atctgtgttt gtaatatatc tgtaaaatta
    19861 gcaatgaaaa tagaatatta gattaaaatt aggttcttaa ttagatgtta aaagggaaaa
    19921 aggttagatg cctttgcagc ccccgctact gtgaaaccaa cgaaactata aataccactg
    19981 tcagtttgat gggaaggtta tagaagtagg atgaagttaa gccaggatac ctgcctaatt
    20041 taatttaaaa caagaggtct tcggggtgaa agatttttaa ttaatatata taaaagtcct
    20101 atctttagaa gtattaggac tttttttaat ttgtttttta gtaaatttta acaaggaggg
    20161 atggaaagtg gggaaaaaaa taatgctaca aggaacagct tcaaatgtag gtaaaagtgt
    20221 cttagtagca ggtttgtgta gaatatttaa gcaagatggt tatactgttg ctccttttaa
    20281 gtcacaaaat atggctttaa attcttttat aactaaagaa ggattagaaa tgggaagagc
    20341 acaagtattt caagcagagg ctgcgaaaat agagccaata gctgatatga atccagtttt
    20401 attaaaacct tctggaaata ataaaagtca agttattgta agaggtaaag ttgtaggaga
    20461 aatgccttct tctaagtatc atgattataa attggagtta gtagatgtgt tgaaggaaac
    20521 atttaatagc ttaaattcaa ggtatgatat tgtagttatg gaaggggcag gaagtaatgc
    20581 agagataaac ttaaaagata gagatatctc taatatgggt atggcagaaa tagctgatgc
    20641 acctgtaata atagtcggag atattgatag aggaggcgta tttgcctcat tagcaggaac
    20701 aatgctttta ttaaatgaag atgagaaaag aagagtaaaa ggtgtaataa tcaataaatt
    20761 cagaggaaaa aaagagcttt tacaagatgg tgtaaagatg ctagaagaca tcataaaagt
    20821 acctgttata ggagtagtac cttatacaga tataaagata gaagatgaag acagtgtaac
    20881 tacgagattt aagaaaaaaa tgaataaaag tgatatacac atagaaataa ttagaactcc
    20941 acatatgtca aattttacag attttaatat atttgagaca caagaagatg taagtattag
    21001 atatgtagac tatggagaat ctttaggaaa tccagatata ttaataatac ctggaactaa
    21061 aagtactata gacgatttaa catatataag aaaaagtggt cttgaatcgc aaatcaaaaa
    21121 tttacatagt caaggtaaat tgatatttgg gatatgtggt ggataccaaa tgttaggtaa
    21181 aaaattaaaa gacccttatc atgttgaaag tgaaattgaa gaagttgatg gaataggtct
    21241 tttagataca gaaacaacgt ttgagaaaga aaagactaca acacaagtag aagctactat
    21301 tgttgaatgt attagtgaat acatgaataa ccttaaggga aaaaaagtaa aaggttatga
    21361 aattcatatg ggaattacaa agcgaggtaa tgatgtaaga agtttagatt taataactaa
    21421 aaaacttgat aaagaagtga attatactga gggaagtgta aataaagagg ggaatgtaat
    21481 tgggacttat cttcatggaa tatttgatga aataagcttt acaagagcaa ttttaaacaa
    21541 tataagaaag aaaaaaggtt taggagaatt agaaagcaaa gtaaactctt ttaatgaatt
    21601 taaggataaa gagtatgata agttggctga ttttttaaga gaacatttag atatagagaa
    21661 aatatatgag attatgaaat aatgatgacc tttatttata atttaggtag gaggtgtatt
    21721 atgaaaaaaa ttttaattgc gggtactaat agtggagtag gtaaaacaac aatatcatta
    21781 ggaataatgc aagctttggt taagagaaat atgaaagtac agccatataa agtagggcca
    21841 gactatatag acccttcata tcacactttt ataactggaa gacattctag aaatttagat
    21901 tcttatatgt tagatgatga aaaaataaag tatatagtaa ataagtcctc aaaagatgca
    21961 gatatttcag taatagaagg tgttatgggc ttatatgatg gctttggaat agatttagat
    22021 aattgtacaa gttcacatac ttcaaaggta ttaaagtcac ctgttatatt agttataaat
    22081 ggtaaatcta tggcagcatc tagtgctgct atggtacttg gatataagga actagataaa
    22141 gatgtaaata taaagggtgt tatagtaaat aatgtaaaga ctaatagcca ttatcaaata
    22201 attaagagtt ctatagaaaa atattgtaat gttgaagtat tggggtattt tcctccaaat
    22261 aacaaattct ctttggaatc tcgacatcta ggattagttc ctagtgtaga aatgaaatca
    22321 ctaagggaaa aattttatac cttagcagat gaaattgaac actatataga tattgacaga
    22381 ataattgaaa tatcagaaag cgatgaattt gagagtgatt ttgattttca aactttaata
    22441 gaaaataata aaataaaaga acatgttaat aataaatcaa tagctatagc atatgataaa
    22501 gcattcaatt tttattatag agaaaatata gagcttttag aggaacttgg tttagaaata
    22561 aactatttta gccctcttga agatgtatca gtgccaaatg cagattatat ttatattgga
    22621 ggaggttttc cagaaatatt tggaaaagaa ttagaagcaa atgagtcaat gagaacttcc
    22681 atattagaag cacataacaa taatatacct atttatgcag aatgtggagg actgatgtac
    22741 ctaggtgaga aactattgaa tcaagaagaa caagaattta atatggttgg aatatttagt
    22801 ggaattagta agatgacatc ttctttaaaa agatttgggt actgtattgg tgtagccaag
    22861 gaaaatactc ttttatctaa aaaaggggaa tctattaaag ggcatgagtt tcatcattca
    22921 atatttgaaa gtgatgaaaa atgtgtatat tcaatgagaa aagaaagaga tggaaatata
    22981 gtagaagagt gggatggtgg ttatagtaaa ggaaacactt tggctacata tcttcatact
    23041 catttttata ataacttaaa ttgtatagaa aattttttga aaaaaggaaa tgaataaatg
    23101 agtattttat ctatttatat aggatatgtg acagacttaa ttgtaggaga cccatattct
    23161 tttcctcatc cagtgagatt tattggtaaa cttataaatt ttactcaagg tataataaga
    23221 aaggtctcta aaaatgatag gcagttaaaa ttggggggat ttatattatg gtttataacc
    23281 gttggaataa catatttaac aacttatgct atagtgaagt tatttagttt taatatatta
    23341 ttgagtattg tagtgaatag ttttataatt tatacaacac tagccacaaa atgtttaaaa
    23401 gacgaagcat taaaaattta taatgtatta aaaactgaag atatagaaaa atctaggatt
    23461 cagctatctt atatagtagg tagggatact actaatttaa gtgaacctga aataataaga
    23521 gcaactgtag aaactgttgc agaaaatact gtagatggta taattgcgcc tatgttttat
    23581 gcatttattg gaggagcacc acttgctatg gcctataaag ctatcaatac attggactca
    23641 acagttggat ataaaaataa aaagtataaa gatattggtt ttgcatctgc taagattgat
    23701 gatatagcca attatatacc agctagaata tctgtcattc ttatgacaat tggaagtttc
    23761 tttttaaatt ataactatag gaactgtttt aaaatctcta ttagagatag aaagaatcat
    23821 aaaagtccaa attgtgcttt ttcagaaggt gcagtatctg gtgctctagg aatacaacta
    23881 ggaggtacca acgtttattt tggggaaaaa gtatataagc caacaatagg ggataagctt
    23941 agggagatag ataaagaaga tataattaaa actaataaaa ttatgtatgc atcttcattt
    24001 gtatctatgt tggtatttac actaatatat gtgttatgta ggatgatttt aattaactta
    24061 attatataaa ttattgtttg ttaacttaag ggggacatag atgaaggatt tagggcatgg
    24121 tgccaatgta gatgaaatgg caagattata tgggaaaaac ccaaaagaaa taattgattt
    24181 tagttcaaac ataaatccaa atgtattacc aaatttagag agatacattt taaaaggatt
    24241 agaagagtgt aggaattatc cagatataaa ttatacaaac ttgagagaaa atatatcaaa
    24301 atatatagat ataaatccag actttataat acctggcaat ggtgcaacag aagtgattta
    24361 tttgcttatg aagagtatta aaaaaaaatt ggctataata aatccgactt tttcagagta
    24421 tagaagaagt gctgagttaa ataatttaga tattatagat ttagagttag atttagaaaa
    24481 taactttaaa cttaatatag atataataaa agaaaatata aaaagatttg atagtttatt
    24541 tatatgtaat cctaataatc cgagtggtaa tgtccaagat ttaaaggaac ttgttcattt
    24601 actagataaa cataataagg tattaataat tgatgaaact ttcatggaat ttgttgaaga
    24661 tgaaagtaaa tatagtttgg ttaaatatat agaatcaaat aaaaatatat ttataattaa
    24721 agctgtgact aagttttttg gtatgcctgg tttaaggcta ggatatggtc ttacaagcaa
    24781 cactgaaatt atgaacaaaa tttatgaaca caaagagcca tggactatca attcttttgc
    24841 agatatacta tccaatttta tttttgaaga taaagagtat attaaaaata gtaaagaata
    24901 ttacatagaa gaaagagaat atatgttaca agagttgaga aacataagaa atataaaggt
    24961 ctatgataca gatgctaatt ttatcttgat aaaaatatat aaaaaaacaa ctaaagaatt
    25021 gaaaaaagat ttgtttaagc aaggaaacat attagttaga gatgcgtcta attttatagg
    25081 attagatgat agttttataa gagtggctat aaaatctcat gaagataaca aaattcttat
    25141 agaaaatatg aaaaatttat tgggtgatta aaatgaaatc ttatggaata tgcccagcat
    25201 cttgtggaga atttgtacaa ggtataattg atgatgaaga atatttatgt tcatatgcaa
    25261 tagatatgta ttctaaagtg tatattgaag aaaaattagt agatataaat ttagggagat
    25321 ataagtcaag gttagcaatt gaaaaggtat ttgaaaaatt taatttacct aaaaaatata
    25381 ctaaaaatat ttctttaaat ataaatagta aaatacctgt tggaaaagga atggcaagtt
    25441 caactgctga tataggagct actataaagg caacattatc attgatagat aaagatttaa
    25501 gtagcgagga gatttctaaa ttagcagcag aaatagaacc aacagattct atatttatag
    25561 ataaaaatag tatatttaat cctctaaatg gaactgttat aaaataccta ggaaatctga
    25621 ccaatgcgaa agttgtaata cttgaaccaa acaaagtact agatactatg aaaattagat
    25681 tgaggcaaga ttataataaa ttaaaagtag agaataaaga agtaataaaa aaatcatttg
    25741 ctcttttaga agaaggattg aaaaaaaata atttatctct agttggagag gcttgtactt
    25801 tgagtagctt agcaaatgag aatatagaaa aaaaagagta tttaaatgaa ataataaaaa
    25861 tatcaaaaaa atatggagca tatggagtaa atattgctca cagtggaact gtagtaggta
    25921 ttttaattga taagtttatg aatgataaaa agatgataga tgccttatgt gaatctaaca
    25981 taaattctgt ctataataaa atttatacac aaaacataat taatggagga attaaggggg
    26041 aaatagaatg gaatacataa agaatcctat gaaaatagaa gaaaaaagtt ttgaattgat
    26101 acaagaaata atagacgaaa ttagaccaga ttataaattt aagaataata tcgaagaaaa
    26161 aataataaaa agagctatac atactactgc tgattttgat tacttagata tattaaaaat
    26221 atcagaagaa gcagttgata gtataataga tgcattaaaa aataatgcaa gtatttatac
    26281 tgatacaaat atggctctta gtggtataaa taaaagaaag ttagaatcat taggatgtaa
    26341 gtataaatgt ttagtggcag atgatgaaac tgtaaaatta gctaaagaaa aaggaattac
    26401 tcgttctatg gcagcagtag aaattgcagc taaagaagaa ggaagaaaaa tattcgtttt
    26461 aggtaatgct ccaacagctt tatataaagt tatggagatg aaatcagaag gtagattaga
    26521 tttagatgca gttataggag ttcctgtagg ttttgtagga gcacaagaat caaaagatga
    26581 agttgaaaaa acagatatac catatataat ttctaaaggt agaaaaggtg gcagtaattt
    26641 agcagcagca atagtaaatg ctatattata tactatgtag gtacctatat ggaagaatat
    26701 gtatatatag atggaaaaaa atatagaaga ggatatacta caggttcatg tgcaacaggt
    26761 gcatctaagg ctgctgtata tatgttgatt acaaaaaata gaattaatac tataaatata
    26821 gatactccta aggggatacc attactacta aaagttgata atataaatat ttctgataca
    26881 tttgtggaat gttccataaa aaaagatggt ggagatgata tagatgcaac tcataccatg
    26941 gatatttatg caagagctga aattgtagct aaaaatgata agaacaaagg gtatcttact
    27001 ctaaaggata tagatagttt aagcaccaat agtgagtgta aaagtgagct ctataagttt
    27061 attagggttt atggcggaac tggtattggt gtggttacga aaaaagggct tagtgtggat
    27121 gttggtaagc ctgctataaa tccgactcca cttaaaatga taaatcatga aataagaaag
    27181 cttataggag ataattttga atctatactt ggaaatgata aagttttaaa aataacaatc
    27241 tttgctccac aaggagaaac tgtagcaaaa aaaacattta atccaagatt aggtatagtt
    27301 ggaggaatat ctataatagg tacaactggg attgttgaac ccatgagtga tgatggttgg
    27361 aagaagtctc tatctataga acttcagatg aaaaaagaac aaggcttaga taaaataata
    27421 ttggttccag gaaatcatgg agaacagttt ataagagaaa aattaaactt agatattaag
    27481 tatgtagtta gggtaagtaa ttttataggc tatatgatta aagaagctca aagaatagga
    27541 tataaaaaaa tcttaatggc aggccatata ggtaaattta taaaagtatc tgctggtatt
    27601 tttaatactc atagtaaggt agcagatgct agaagtgaga tattagtggc aaacttagct
    27661 ttaatgggag ctagatacga atttttaaat aaaataaatc aatgcgtaac tactgaagaa
    27721 gctgtagagc taataaataa tagtgaatat agagaagtat ataatatatt aagtaataaa
    27781 tgtagggaga gagtaaagca atacttgaat gaagattcag atgatattga tgtggaagta
    27841 atcatatttt caatggataa gtctttatta ggtaaatcgg ataatacaga tgatttagtg
    27901 gaggtcttta tatgataaac ataataggtc taggacctgg taacttagac tatataacaa
    27961 aaaaaggtga aaatttaatt tccacttctg atgtattaat tggtggtaaa agaaatttag
    28021 agtctataaa aaattttgaa ggagaaaaaa tagttctgga ttctaattta agagaaatta
    28081 tagagtacat aaataacaat aaagaaaagc aaatatcaat aatagcatct ggggacccat
    28141 taatatatgg gataggtaga tatctatcta aaaatattga taataagatg ttaaacatgg
    28201 tttctgggat tagttcatta cagtacatat tttcaaaaat atatgtagat atgaatgatg
    28261 tatatattac aagtagtcat ggcaaagtac cagattttga ttacatatta tcacataaaa
    28321 aagtatgtat ggttacagat tcaaagatag gaccaaaaca aataagtaga gaaataatag
    28381 atagaaatct aaataaaatt attgttgtag gagaaaatct gtcatatgac aatgaaaaaa
    28441 taacaatagc aaaaccagaa gagataataa gaatggacaa ttttgatatg aatgttgtgg
    28501 tgattttaga tgaggaatag tgaatttata acaggtaaag ttccaattac taaggaagag
    28561 gttagagcaa tatcaataag taagttaaat ttagtaaatg ctaaaaacct catagacata
    28621 ggggctggta caggaagtgt aagtgttgaa gctgcatata attatcctaa tttaaaggtt
    28681 atatctatag agaaaaatga tgatgctata gagcttatag agaaaaataa aaaaaaattc
    28741 aacttaaaaa atatagaagt gataaaagga tatgctccaa ttaatctagg gttaaatgtt
    28801 aaagttgagt ctatttttct tgggggaaca ggaaataatc tggaagaaat aatagaatgg
    28861 tctaaaaaaa atctcgttac aggaggaaga cttgtagcta attttataat aatagataca
    28921 tttaatcaaa ctttaaaact gcttaaaaag catggattta aagaaataga tgtatgtgtt
    28981 ttgaatgttt ctaaactaga gaaactagga aaaggtgaat attttaaacc actaaatcct
    29041 atatatataa tatcttgtga aaaaggggaa aatgatgatg aataaagtac attttgtagg
    29101 agcaggacct ggagataaag agctgataac attaaaagga tacaaattat taagtaatgc
    29161 agatgtagtg atatatgcag gttcacttgt taatcctgaa cttttggaat actgtaaaga
    29221 agattgccaa atacataata gtgcacatat ggatttacaa gagataatag atgttatgag
    29281 agaaggtata gaaaataata aatctgttgt aagactgcaa acaggtgatt tttctatata
    29341 tggttcaatt agagaacaag tggaagattt aaataaattg aatatagatt atgactgtac
    29401 tccaggagta agttcttttt taggggcagc atcatcttta ggggttgaat atacagttcc
    29461 agaaatttct caaagtgtaa ttataacaag aatggaaggc agaactccgg ttccagagaa
    29521 agaatcaata caatcatatg ctaagcatca gacatctatg gtaatatttt tatctgttca
    29581 agaaattgag aaagttgtgt ctaaattact ggaaggtgga tatccaaaag atactcctat
    29641 agcagttata tacaaagcaa cttgggcaga tgaaaaaata gttaaaggaa ctttaagtga
    29701 tatagctgta aaagttaaag aaaacaacat aaataagact gctttaataa tggttgggag
    29761 atttttagga gaagagtata ataattcaaa gttatatgat aaggatttca aacatgaata
    29821 tagagggtaa tattgctata atctgtatta cagaaaatgg aaaaaaatta gctctaaaga
    29881 taaattctct agtaaataac tgtgttatat atcatgtaaa aaataaaaaa agtaatttag
    29941 ttgttgaaga aacatgtgtg catacagttc aaaagaagtt aagtgatttt gtaggagaaa
    30001 tatttagcaa atttgattac atagtattta taatggctac aggtatagtt gtacgaagta
    30061 tagcaccata cataataagt aagtttagtg accctgcaat tttggtaatg gatgaaaaag
    30121 gcaaaaacgt aataagttta ttgagtggtc atattggagg ggcaaacagc ttgacacagt
    30181 acataagtag tcttattgat gctaatccag taataacaac agctactgat ataaatcaaa
    30241 aagcttcctt agatatgata gcaaaaaaac taaatgcaca tattgataat tttagagaaa
    30301 gtgtaaaaga agtaaattct atgctagtga ataataaatg tgttggatta tatattgatg
    30361 aaggatatca agttgatact aggggattta aacttataga aagtaaggat gagttaagag
    30421 atagtttttc aaacacatat atagaaaaat tagttgtagt aagcaataaa ataaattgta
    30481 ttgaagatat tgagaattta aacctagata ataaatttga acattgctat agtaccaaaa
    30541 aaataataaa ggtaattcca agagatatag tgataggaat tggttgtaga agaaacacag
    30601 atagtgaact gatgtataat tcacttgaag agtttcttaa taaacaaaat atagatatta
    30661 gagcaataaa cacagttgga agtatagaac tgaaaaaaga cgaaaaagca ataattgaat
    30721 tatcaaaaat attgaaggtg ccatttaaaa cattttcagt agatgaaata tctaaggttg
    30781 ataatctttt tgataaatct gattttgtta aaaaaaatgt gggcgtgtat tcagtagcag
    30841 aacctgtagc atatcttttg agcaaaggta atttgttagt tgaaaaacat aaatataaag
    30901 gaataacttt ttcagtgggg agaataaaaa tatgatatac gttgtaggaa ttggaccagg
    30961 aagtaaagat acaatgactt tagaagcaat aaaagcaata gaagattctg aggctattgt
    31021 tggatataag acttatataa aactaataga agaatttata caagataaag aaataatcca
    31081 aaatggtatg aggcaagaag ttgatagatg taaacaagca gtagaggaag caaaaaaagg
    31141 aaaaaaagta gcagttgtaa gcagtggtga tgctggaata tatgggatgg caggtcttat
    31201 tttagaatta atatctaaag aagatgaaga tataaaagta aaggtaattc caggtgttac
    31261 tgcaagtatt ggtgcagcag ctatacttgg agctcctatt atgcatgatt tctgtcatat
    31321 aagtttgagt gatttaatga ctccgtggga agtaattgaa aaaagattga gattggccgc
    31381 tgaagccgat tttgtaattt gtttgtataa tccaagaagt aagggaagaa gtgaacatct
    31441 aagcaaagca tttaaaataa tgggtgagtt taaaggtgga gatacacctg ttggagtggt
    31501 aaaagatgta ggtagagaaa aagaagaaaa gtttgtatgt acttttgaaa atatggactt
    31561 tgaaaaagtc gatatgacta caatggttat aataggaaat aagtctacct atattaatgg
    31621 tgaattgatg ataactccaa gaggttatac agtatgattt taattttagg aggaacttca
    31681 gatagtttat ctatatgtga taagataaat gaactgaaaa atcaaccata tatcctttca
    31741 gttactacag attatggaag ggaacttgca caacaacatg cagagaatgt aattttaggt
    31801 aagcttggaa aagaagatat gctaaaattt ataaaagata ataatatagt aaaaataata
    31861 gatgccactc atccttatgc agttgaagta tccaaaactg ctattacttg tgcaaaacta
    31921 ttgaatatag attatataag gtttgagaga aaatctttaa ttgaagaaat agattatgat
    31981 aataaattta tagtagatac aattgaagaa gcctgtgaaa tagcaaataa aatagggaca
    32041 aatatattca taggaacagg aagtaaaaat ttgaacagat ttatagagga aataagtgat
    32101 aaaaatttag ttgttagagt tcttccaacg agtgaagtca tattaagttg tgaaaaatta
    32161 ggtttaagtg cagataatat agtagctatg aaaggtccat ttagccagta tataaatgaa
    32221 gaaacatata aacattacaa tatagattta gtcataacaa aagaaagtgg aatagctggt
    32281 gggttcttag agaaggtaaa tgcatgtaaa actttcaata taccagtaat aattataaaa
    32341 agagaatcga ttaactacga aaatgtattt aatgacataa ataaaattaa agacatactt
    32401 gtgtaatttt taggaggaga atatatgaag aaagccttat tagtagtgag ttttggtaca
    32461 agctatcatg aaacgagaga aaagacaata gatatatgtg aagataaaat aaaaaattcg
    32521 ttaaaaagcc atgatttttt tagagcttat acatcaaata tgataataaa taaaataaaa
    32581 aaaagggatg gaatagaaat agataatcca atacaggctt tagataaaat atatgaacaa
    32641 ggatatgatg aagtaataat ccaaacactt catattatat gtggcgaaga atttaacaaa
    32701 ttaaaagaac aagtagatgg atattcttct aaattcaaaa agattgtatt aggaagacct
    32761 ttgcttacac atattgaaga ttatcaggaa gctgtagagg caattaagca tcaaattcct
    32821 catatggaaa gtaatgaagc agtagtattt atgggacatg gaacacttca tgaatcacat
    32881 tcagcgtatc cagcattgga atacatgctt agggataatg gaataaatgc ttatgttggt
    32941 acagttgaag ggtatccaga aatagaacat gtaataagaa gattaaaaga aggaaatata
    33001 aaaactgtaa atttgatgcc atttatgtta gttgcaggag accatgctat aaatgatatg
    33061 gcaggagatg aagaagattc ttggaaaaca atattagaag aaaatggatt taacgtaaga
    33121 gttcatttaa aaggactagg agaaaattct tatatacaag ataaatttgt tcgtcatgct
    33181 gtaaaatgtg cagagaatgc gaagttctat ggtataggag cagggccagg agatggttct
    33241 ttacttacga taaaagcggt taatacttta aagaaactgg atattctata cactccagaa
    33301 tcaaaaaagg gtggagatag tctagcttta tcaatagtta gtgaatattt acctgaatca
    33361 gtggaaataa agtctaggca tttcccaatg agttttgatg ggaatgaaaa aagtttagct
    33421 tgggacaatg tggcacaaga aattatatca gatgttaatg atggtaaaaa tgtaggattt
    33481 gttacattag gagaccctat gatttatagt acatatgtat atataatgaa aagaatatta
    33541 ggagaggtag aagtcgaaac tataccagga atttcatcat tttccaatat agcatctaat
    33601 cagaattttc cattagtcat ggataaagaa gctttagtgg taattccttg tactatggaa
    33661 gatgataaga tagagtatgc tttgcaaaat tataattcaa tagtattgat gaaagtatat
    33721 aaaaatttta aagaaataat aaaaaaatta gaaaagtatg atttaataga acatgctatt
    33781 ttagtaagta attcttccca agaaagcgaa aatgtgttta cagatttaaa agaagcgcac
    33841 cttgaagata agatatctta tttttctact atactagtaa ataaagataa taaaataaaa
    33901 taggtgaaag caatatttaa aggagactta atatgaatat agtggttgga actaggggta
    33961 gtaatctagc gcttatacaa acagaatggg taataaatga attaaaaaag aagtatccag
    34021 aaattagttt tgagattaaa atcataaaga caaaaggaga tttaattcaa aatgtttcac
    34081 tggataaaat aggtgataaa ggattgtttg tcaaagaaat agagcaacaa ttattagatg
    34141 gaaaaataga catagcagta catagtatga aagatatgcc ttcttattta gcagatggac
    34201 taaaatttgc tcatacgcct aagagagaag acccaagaga tgttctaata cttagagaag
    34261 gatataaaaa tttagatgat ttacctcatg gagcagtaat aggaacagga agtaaaagaa
    34321 ggaagtttca attattgaaa caaagacctg atttaaatat agtacaagtt agaggtaatg
    34381 tggaaactag gatacgaaaa ataaaagatg aaaacatgca tggtattgtg ttggcagcat
    34441 caggaataat tagagctaat ttgcaagata aaataagttc ttatttacct gttgatgttg
    34501 ttattccagc acctgcccaa ggagctttag ctatagaaat tagaagcaat gatagtgcga
    34561 tagagggaat agtaaattca ctgaaggatg agaatacaga aatccaaata ttggctgaaa
    34621 gaggtttttt agatggtgta aatggaagtt gtcatattcc aatggcagct tattgtgaaa
    34681 taatccaaga taaaatacat cttactggct tatatggaga ttcagaagga aaaaaagtag
    34741 taatcaagtc tatagatgga gatatttctt ctcctagaga gttaggttta aagttagcta
    34801 aacttgtatt gaaggagtat gagaattatg aagggtaagg tttacttagt aggggcagga
    34861 ccaggtgatt ataaactcat gactttaaaa ggtttagagt gtataagaaa atcggatgta
    34921 atagtatatg atagattagc aaatagtagt tatttaagag aagctaagcc tgattgtgaa
    34981 cttatatatg taggcaaggc atcaagtaat catattttgc cacaagaaga tataaataga
    35041 attatagcag aaaaagctaa agaaggaaaa attgtaactc gtcttaaagg aggagaccct
    35101 tatgtatttg gcagaggggg agaagaagca gagactttag tagatgaagg tatagaattt
    35161 gaagtagttc caggtataac ttctgctata ggaggtttat gttatgcggg tattcctata
    35221 acacatagag accatgcttc gtcatttcat gtaataacag gtcatttgaa gggtgatgat
    35281 agtggagaac taaactggaa tgctcttgca aataacaaag gtactcttgt gtttttgatg
    35341 ggaatttcaa acctagagaa aataagtgaa aacttaatga aagaaggaaa agataaggat
    35401 acacctgttg ctcttataag ttgggcaact agatataatc aaagagttgt tacatctaca
    35461 cttgaaaatg tttatgaaac tgctattaaa gaagaagtaa aaccgccaac tcttatagta
    35521 gttgggagtg ttgtaggact tagagaaaag ttgaacttct ttgaaagtaa gcctttattt
    35581 ggaaaaagta ttgctgtaac taggtctaga aatcaaaata gtgtattggt agaaaaaata
    35641 atggatttag gtggaaatcc tatagaaata cctactatta aggtagaaaa aatacaaaat
    35701 aatattaact tagaaaatga aataaaaaat ataaataagt ataattatct aatactaact
    35761 agtaaaaatg ccgtagaaat cttctttgaa aagatatatg aaatgaattt tgatttaagg
    35821 atattatcta atttaaaggt atgtgctata ggttctgcta catcaaatga gttgaaaaaa
    35881 agaggaatta tagcggatat agtaccaaaa aaatttgtag cagagtcact gtatgaagag
    35941 ttagcgccta ttttaaatga tgacgataat atacttatac ctagagcaga aaatgctaga
    36001 gattatctgg ttgacaaact taaggctatt tgtgaagtaa cagaagtaca tatatataga
    36061 acagtaatag atgaggagaa aaaaggtgag atattagata ttttaaattc taatgacata
    36121 gattatataa catttactag ttcctcaaca gtaaataatc ttgttgaaat tataggaaaa
    36181 gaaaatatta aaatattaga aaaaataaaa acactatcta taggtcctat aactacagag
    36241 acaataaata gtttgggaat aaaattgtac aaagaatctg ctacatctac tatagattcg
    36301 ttagtagatt taattataaa aaattaattt tggaggcttg aatatgttaa gaagaccaag
    36361 aagactaaga gcaagtaaag caatcagaaa tttggtaaga gaaactaagg tgaatgtaga
    36421 agacttaata tatccactgt ttgtagtaga gggggaaaat ataaaagaag aaattaaatc
    36481 tttaccagat gtctatcatt tatcaataga tatgctagaa gacgaaataa aagaaataag
    36541 tgagttggga attgaacata taatgttatt tggtgttcca gatgaaaaag atgagtgtgc
    36601 ttcacaagct tttaatgata atggaatagt tcaaaaggca attagaaagg taaaagaaat
    36661 aaattcagat ataaatgtaa taacagatgt ctgtatgtgc caatatacaa gtcatggaca
    36721 ttgtgggatt ttaactgata ctggttatgt tgataatgat aaatcattgg agtatttggc
    36781 taaaatatct gtaagccatg ctaaagcagg agctgatatg gttgctccat ctgatatgat
    36841 ggatggaaga atacaagcaa taagagaagc tttagatgaa aatggattag aaaatgttgg
    36901 aatcatggct tatagtgtta agtatgcttc aaattattat ggacctttta gagaggcagc
    36961 tcattcagca ccatcttttg gagatagaaa aacatatcaa atggacccag caaatagcaa
    37021 tgaagctata atagagactg aacttgatat attggaaggt gcagatatac ttatggttaa
    37081 acctgcatta tcatatttag atattataag aagagttaaa gataattttg acttacctct
    37141 agcagcttat aatgtaagtg gagaatactc tatgcttaag tttgctgtga aggaaggttt
    37201 attaaatgaa gatgtaattc ttgaatcaat tacatctata aaaagagcag gagcagatat
    37261 aataataact tattttgcta aagacattgc taaactgttg aaaaaataaa ttctagcagt
    37321 ataaagaata tcaaaaagta taggaattgt aattaactat tatacagtag ttttgtttag
    37381 acatttattg aagaataata gaaactaatt tgcaatttct atactttatt tatgtaacta
    37441 aataaaattt ggaggtagaa gatgctatat cctattaatt taaaattaga tgagttagat
    37501 gtagttataa ttggtggtgg agaagttgca tataggaaat gtaaaaattt tttagagttt
    37561 aacaaaaatg ttactatagt ttctaaacaa attttaaata aattttatga tttaaaagga
    37621 aatataaaaa taataaaaga tgattataaa gaaatatata taaaagatgc ttctgtaata
    37681 attgctgcca caaataatag agagttaaat atggaaatag gattatattg taaagcaaaa
    37741 aataagctag tgaatgtagt tgataatata gaaatatcga actttactgt tccatcatat
    37801 ataaaaagag gagatttact tataagtgtg tctactgggg gcaagagtcc ttcattatca
    37861 tcaaagataa aaaaagaaat tgaagagaga tatactgaag attatgagga gtatttaaat
    37921 gtattaggag atataagaaa aaaggttata aaaaaatacg aagataaaag taaaagaaaa
    37981 gatgtgctta atatgttggt aacacttgac ctagaagaac ttaagaagtt tgatatataa
    38041 aaaataaaat aaaaaatgtt aaaaaggtgt tgacggatta tttttaag
//
LOCUS       DAEPKC010000030        37224 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.030, whole genome shotgun sequence.
ACCESSION   DAEPKC010000030 DAEPKC010000000
VERSION     DAEPKC010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 37224)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37224)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37224
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.030"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(<1..828)
                     /locus_tag="KR294_001574"
     CDS             complement(<1..828)
                     /locus_tag="KR294_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBH0239656.1"
                     /translation="MNINYLYYFQTVCKYKNMTKAAESIHISQPSITLAIKELEKELG
                     FELFYRIGNKIELTPEGKIFLDKSKHFIKQFEDFQCDALDLGKKRKASLKIGIPTVLG
                     TFLLSKILPRFNVIYPDIELKIFEVPTFVGAKMIEESTLDFCIGIIDSDIYDDIDSKT
                     IYKTELYLVTNPKNELAKHPIISNYMLKNVPFVILSEGSYHYKIITKRLEKAKPNIIL
                     HSNQLSTIRYLLENDLASTILYKEIFQNTENLCSIPLERAITANIGVLWRRNQYISHS
                     "
     gene            1245..2648
                     /locus_tag="KR294_001575"
     CDS             1245..2648
                     /locus_tag="KR294_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239657.1"
                     /translation="MKGSDLVKFELMDFLMNPFVLMFAAVITGILFGKIKFGKFNFGV
                     SGALFTGLFIGWLAYSLGNLIIAKGETAAGYKAATVMMGNGIISSDFFDFFLIIFVAA
                     VGLLAAKDMKAVLKKYGARFVILGVLITFIGGSMTYAMTLLSSDKGSSAYEVSGVYTG
                     ALTSSPGLAAALETAGKHAEDVSKEFEKASIKDKKEILKVVDPEGKLDVNTTTSLTQE
                     QIDKYIAYAEAGVGIGHAVAYPFGVLIVILGVNFLPKLFRMDLKEERRKYEKEMKEAR
                     DSVSGKTIPEVPFNIITFFLTCLAGYLVGGIHVFMGPLGYFTLGATGGSLIVSLVLGY
                     IGKIGVVNFRMEEKVLNILKQIGLVFFLAIVGLRYGGKVVDSIMTSGMHLALVAIAVG
                     VTAMMIGFLVGKYVFKLNWILLSGAVCGGMTSTPGLGAAVDALDSDDPAAGYGATYPF
                     ALLTKVILVIVLHKLPM"
     gene            2675..4219
                     /locus_tag="KR294_001576"
     CDS             2675..4219
                     /locus_tag="KR294_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA hydrolase/transferase family protein"
                     /protein_id="HBH0239658.1"
                     /translation="MNNEGAFEELSGRLRNKELCDLIMNADEAAKIIEDGMVIGVSGF
                     TPSGYPKAVPLAVSERAKSGEKIKLTVYSGASLGPEVDGAWSEAGIIERRLPYQTNSI
                     LRNNINKGVVDYIDMHLSHSTQFLNYGTIPKVDVAIVEALAITEEGNIIPTSGIGNSP
                     SFIKSADKVIVEINLAKPMEMEGMADIYITENPPNRKPIEINHPKDRIGTTYIPCGLD
                     KIAGVVITNMQDKTRPLGVVDEASKKISNNIIAFLREEVKSGRLSKNLLPLQSGVGSV
                     ANAVLYGLCESEFENLTCYTEVVQDSMLDLIRMGKVTMASTTSVSPSPEGLIKFEKDI
                     DFFKDKIILRPQEISNNPEIARRIGVIAMNTAIEVDIYGNVNSTHIMGSKMMNGIGGS
                     GDFARNGAITIFSTESIAKNGDISSIVPMVSHVDHTEHDVMVIVTEQGYADLRGLAPR
                     ERAIKIIENCAHPDYKEQLRDYLNRACKSGAKQTPHILDEALSWHSKFMSTGTMKKAE
                     TFKSAL"
     gene            4250..5641
                     /locus_tag="KR294_001577"
     CDS             4250..5641
                     /locus_tag="KR294_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase family protein"
                     /protein_id="HBH0239659.1"
                     /translation="MEKAVENFEDLSKEYINGYIERARKAQREFECYTQEQVDKIVKI
                     VGKVVYYNAEYLAKLAVEETGMGVYEDKVAKNKSKAKVIYNNLKDKKSVGIIDIDRET
                     GITKVAKPVGVVAAITPCTNPIVTPMSNAMFALKGRNAIIITPHHKAIGCSTKTVEMI
                     NEELEKIGAPENLIQILDQQSRENTRNLISSADVVIATGGMGMVKAAYSSGKPALGVG
                     AGNVQCIIDRDVDIKEAVPKIIAGRIFDNGIICSGEQSVIVAEEMFDKIMDEFKNNKG
                     FIVRDKVQKEAFRNAMFVNKSMNKDAVGQSVHTIAKIAGVEIPEDTKIIVIEADGPGE
                     EDIIAKEKMCPVISAYKYKSFEEGVAIAKANLNVEGKGHSVSIHSNTVKNIEYAGENI
                     EVSRFVINQCCATSAGGSFFNGLAPTNTLGCGSWGNNSISENLDYKHLINISRIAYYM
                     PENEVPTDEELWG"
     gene            5834..7330
                     /gene="abfD"
                     /locus_tag="KR294_001578"
     CDS             5834..7330
                     /gene="abfD"
                     /locus_tag="KR294_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxybutyryl-CoA
                     dehydratase/vinylacetyl-CoA-Delta-isomerase"
                     /protein_id="HBH0239660.1"
                     /translation="MALMTGAQYIESLRKLNTKVYMFGEEVKNWVDHPMIRPSINCVA
                     ATYDLAHDPEYADLMTVTSNITGEKINRFGHLHQSVDDLIKKVKMQRLCGQKTASCFQ
                     RCVGMDAFNAVYSTTFECDKAHGTNYHDNFVKYLTYIQENDLVVDGAMTDPKGDRSLS
                     PSAQPDPDMFLHIVERREDGIIVRGAKAHQTGSINSHEHLIMPTISMTEADKDYAVSF
                     AVPSDAEGVFMIYGRQSCDTRKLEEGADVDLGNKEFGGQEALVVFDNVFVPNDRIFLC
                     GEWDFSGMLVERFAGYHRQSYGGCKVGVGDVIIGAAALAADYNGANKASHIKDKLIEM
                     THLNESLYCCGIACSSEGHKTEAGNYQIDLLLANVCKQNVTRFPYEIVRLAEDIAGGL
                     MVTMPSEKDFKSDLKVGTSGMTIGEVCNKYFKASSVASTEERMRILRFLENICLGSSA
                     VGYRTESMHGAGSPQAQRIMISRQGNINQKKELAKKIAGIKKEEALNL"
     gene            7465..7740
                     /locus_tag="KR294_001579"
     CDS             7465..7740
                     /locus_tag="KR294_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239661.1"
                     /translation="MTCGVRFCGGCNPRYERGKALTIIKEHFNGRVDFSIAQENVEYD
                     LLLIIGGCATLCASYQQYKVKNECVKMWDFSHIERVINVIESAICET"
     gene            7764..9071
                     /locus_tag="KR294_001580"
     CDS             7764..9071
                     /locus_tag="KR294_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA hydrolase/transferase family protein"
                     /protein_id="HBH0239662.1"
                     /translation="MSWQELYQSKLCSATEAVKQIKNGDTVVFAHCVGEPPALVEAMI
                     ENAEQYKDVEIKHMVSLGSGGYTAKGMEAHFRVNPMFVSGNVRKAIENGDGDFTPAFF
                     HEVPKLLREKRLKCDVVLAQVTPPDEHGYCSLGTSVDYTYEAIKTARTVIVQVNDQFP
                     RTYGEVVHVSEFDYIVEKSQPLFELQPAKIGEVEEAIGKNCASLIEDGSTLQLGIGGI
                     PDAVMLFLTDKKDLGIHSEMISDGTLALYEKGVINGKYKNFDKEKMTVTFLMGTKKLY
                     DFANNNPAVEVKPVDYVNHPAIIMKQHKMVSINSAIQVDLMGQVVAEAMGLRQFSGVG
                     GQVDFIRGVSMGEDGKAIIAMPSITTKKDGTVISKIVSIVDEGAPITTSRNDVDYIVT
                     EYGIAELKGKSLRERARNLINIAHPSVRESLAVEFEKRFKEKY"
     gene            9091..10209
                     /locus_tag="KR294_001581"
     CDS             9091..10209
                     /locus_tag="KR294_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxybutyrate dehydrogenase"
                     /protein_id="HBH0239663.1"
                     /translation="MEALRVVPKIFYFDTFKEFNEEFKIGKNDLVITNEFIYEPYMKP
                     LGIDTNLIFQEKFGTGEPSDEMIDSMTKEMKKYNFDRIIAFGGGTIVDICKILALDVP
                     EKSIDLFEGEVSPKKVKELVVVPTTCGTGSEVTNVAIAELKSKHTKKGLAVEETYADY
                     AVLIPETVKGLPYKFFVTSSVDALIHAIESYLSPKASPFTEMYSLQAIKMIMDGYKKI
                     VDKGEEERFNHLRDFVLASNYAGIAFGNAGCAAVHALSYSIGGAFHVAHGEANYQFFT
                     EVFKMYSRKKPNGKIIKCTKILADALECDPNCDVYGELEKFLNKLIAKKALREYGMVE
                     SQIDEFTDSTIANQQRLLANNYVELSREEIREIFANLY"
     gene            10496..11416
                     /locus_tag="KR294_001582"
     CDS             10496..11416
                     /locus_tag="KR294_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HBH0239664.1"
                     /translation="MYKSVNFSKKSVLINSFLSKFLKIIGWGLVSLFTLSALVLSTIS
                     IIIGWAVILPIQVCAVFLLIGGVCIFKGKRLGDQISRYKKYCTIINNRNIIPVELIAE
                     NTSKSLNFIIKDVQKMIDKNYFINTYIDKRNNQIVLTNEDFVPPRYEDVAYEVKEEEK
                     TDESNEVDTIINKGMNYLTQIKEANKNIKSESMGDKIVQVEDVTSKIFDVVKHDPSKL
                     TQIQKFMDYYLPTTLKLLNSYHTLEEQGIDRENITTTMESIENTMNTIVVAFENQLDY
                     LFEDEAIDISTDITVLENMLVQEGLTSGKF"
     gene            11531..12688
                     /locus_tag="KR294_001583"
     CDS             11531..12688
                     /locus_tag="KR294_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HBH0239665.1"
                     /translation="MNNLDDIPVMPTLTLDPFGEESNTNDIDNSDLLMKKDEKDPEEE
                     KLSESERKMVKEFAEKIDITNTNMILQYGAGAQKKVASFSETALKSVKTRDLGEVGDM
                     LTNLVTDLKAFSADEKEQSGFLGIFKKANNKISNLKTKYDSAEVNVDKVSKELQKHQV
                     KILKDIAMLDKMYELNLAYSKELTMYIIAGKQKLKDMKEYEMPKLREKARLSGSTEDA
                     QSVNDMVSLCDRFEKKIHDLELTRMVSLQMAPQIRLVQNSNNLMAEKIQSTIVNTIPL
                     WKNQIVLALGISHLNQAMKAQREVSNMTNELLLKNAETLKMGTIETAKESERGIVDID
                     TIKKTNQSLISTIDEVVKIQHDGRIKRQEAEVELSKIENELKSKLLEFTVK"
     gene            complement(12769..13665)
                     /locus_tag="KR294_001584"
     CDS             complement(12769..13665)
                     /locus_tag="KR294_001584"
                     /inference="COORDINATES: protein motif:HMM:NF033516.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBH0239666.1"
                     /translation="MLKKVKYPIGQVKVSDKFKTIKLLSRKYSISSMCKLISVSRSGY
                     YKWLSYSKKSSDRGIKDRIIKDYIIEIHKKYRGTYGRKRICTYLNKILDTPINHKRVY
                     RLMKELGIKSIIRKKVYRRKFKSYEIYDNILNREFRANQPLEKICMDITYIPIGKKFL
                     YMNVAKDLFNGEIVAYEISTKMDTKLVNNTVNQLINMNLAKDCILHTDQGSQYTSRSY
                     SKRLKDNGIIQSMSRRGNCWDNAPIESFFSHFKSELIYLIDTTDPKEMISLINDYIYF
                     YNNERIQLKNGMSPIEYRTHSE"
     gene            complement(13623..13940)
                     /locus_tag="KR294_001585"
     CDS             complement(13623..13940)
                     /locus_tag="KR294_001585"
                     /inference="COORDINATES: protein motif:HMM:NF013677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBH0239667.1"
                     /translation="MSKKHKKYSKELKLKAVNLYIKEGYSSYKIAEMLNIRSKTQVQN
                     WVKDYKNKGKTAFDDETRGRFKNISLENDNRKFKSVEEELKYLRMENEFLKKLSTLLD
                     KSK"
     gene            complement(14077..15576)
                     /locus_tag="KR294_001586"
     CDS             complement(14077..15576)
                     /locus_tag="KR294_001586"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HBH0239668.1"
                     /translation="MAFYFDTPSHTFSEYLLVPGFSSTDCIPANVSLKTPVTKFKKGE
                     EADIYMNIPLTSAIMQSVSDDKMAIALAKEGGISFIYGSQTIEDEAAMVARVKSHKAG
                     FVVSDSNIKPDNTLKDILDLKEKTGHSTVAVTEDGTSTGKLLGIVASRDYRISRMDLD
                     TKVSEFMTPMSSIVYANKDVTLKEANNIIWDHKLNSLPVLDDNGNLMYMVFRKDYSSH
                     KENPLELLDSSKRYVVGAGINTRDFAERVPALVEAGADVLCIDSSEGFSEWQKITLDF
                     IREKYGDTVKVGAGNVVDREGFLYLAEAGADFVKVGIGGGSICITREQKGIGRGQATS
                     IIEVAQARDEYFEKTGIYIPICSDGGIVYDHHITLALAMGADFIMLGRYFSRFDESPT
                     NKVNINGSYMKEYWGEGSARARNWQRYDLGGDKKLSFEEGVDSYVPYAGSLKDNVTLS
                     LSKVRSTMCNCGALSIPELQKNAKLTLVSSTSIVEGGAHDVMLKDNRNL"
     gene            16172..17596
                     /locus_tag="KR294_001587"
     CDS             16172..17596
                     /locus_tag="KR294_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICB"
                     /protein_id="HBH0239669.1"
                     /translation="MSSSNQSTIKTSIQRVGKFLSGMVMPNIGAFIAWGLITALFIPT
                     GWMPNEKLSTIGDPMIKYLLPLLIAYTGGKAIAGQRGGVIGAAAAMGVIVGADIPMFI
                     GAMIMGPFAGWVIKKFDKFVDGKIPTGFEMLVNNFSIGIIGMLLAILGFYAIGPAIVA
                     GTALIESGVQFIVSKSLLPLVSVFIEPGKVLFLNNAINHGILGPIGIAEAKEAGKSIM
                     FLLESNPGPGLGVLLAYWMFSRGSVKQSAPGAVIIHFFGGIHEIYFPYILMNPVLILA
                     TMAGGAAGILTFSILGAGLVAAPSPGSIFALMALAPKGGLLPVLAGVAVATVVSFLVA
                     APFVKRASANESEEDSTSLEEAKAKMSDMKSASKNSEKNIEKKQLEVNEIKKIVFACD
                     AGMGSSAMGASRFKNRIKNLDLDIEITNSSVDNLPDDTQIVVTHNTLVERVAKNNSSV
                     EIVSINNFLNDPNLDTLFKRLESK"
     gene            17631..19760
                     /locus_tag="KR294_001588"
     CDS             17631..19760
                     /locus_tag="KR294_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBH0239670.1"
                     /translation="MKKKKITSRQKKIILMIVENSKKNIPITISEIAGTLELSSRTVL
                     RDMSGIEKWFDENDFNFVKKPGVGLILEENIENQNFIIELLEEEKIEKEYSKEERNLI
                     ILSKLLVSNEPVKSYYFAKILKVSEGVLNNDFSLASKWLERFDIELVRKPGLGVYLKG
                     QEKSFREAYVNLIYDSFNEKEILDMVRNISENIQTDKAIEILSENRLLNLMDRCIIIK
                     VEATLTKKLSDLDVNLADSAYIGLVVHISLALQRIKNGENITMDKEFLKELSITEEFK
                     LAKEIVKGMETDFNMDIPVDEVGYITMHIRGAKQRSSSNHKALNLDDIEIMEITNKMI
                     DLAEDEFKISLKNDERLFKDLANHLGPSINRLNMGLEIRNPLLDEIKSKYSYAYDGVE
                     KISRIIKDKLNINSIPESEIGYIAMHFASAIEKNLMMNTNINIVVACPTGIGTSRFLS
                     TKIENKFPNLNILETISAINIDEEYLKGKDVDLIVSTVELNTSLNYICVGPFMSLDDE
                     QIIKEKIKSIAQNKLINLNTKNDTKSKNKVYEQITESMNIGKDILQFLEEIRFEKFES
                     KDLSELIEDSSKIFAKSSEDIMSIKESLKERLKISIPYIEESKILLLHCMSERIDIMK
                     LSIIKLENRIVLDSNEEIDNVVFMLLPKNSPSYQRQIMSEISGSLIDNIIFTNKINKF
                     SIEEMTLEVKDIVFNFYTNRLKAFIDE"
     gene            19790..20212
                     /locus_tag="KR294_001589"
     CDS             19790..20212
                     /locus_tag="KR294_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH0239671.1"
                     /translation="MSKVLNENNIFLGLDSVSKEEAITLAGRKLVENGYVKEEYIPAM
                     LEREKVMTTYMGMGVAIPHGVNEAKKEILSSGIVILQFPNGIDFDGEKAYLLIGIAGV
                     GDEHLEILSNIAVVLDDDLTERLKNSNDKQAFMEAFAK"
     gene            20231..21382
                     /locus_tag="KR294_001590"
     CDS             20231..21382
                     /locus_tag="KR294_001590"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HBH0239672.1"
                     /translation="MKKAIQFGAGNIGRGFIGGLLVKSGYHVVFADVNEEILNSINKD
                     KKYTIHIRDVECIDEVIDNISAVSSIKEEIIDEIVQAEIITTAVGPLVLTKIASTIAK
                     GIKARKEKGLTSNLNIIACENAIYASSSLKEEVLKYLNKEEVEYLEIYVGFPNCSVDR
                     IVPPGKNENPLDVTVENFYEWNVEKQGFKGEIPTIVGMNLADNLMAYIERKLFTLNTG
                     HAITAYIGYLKGYKTIEESIKDKFICDIVKSAMVESGEGLIKKYNFDSEAHYKYIDKI
                     LNRFKNPYLNDDVLRVGREPLRKLSDKDRLIKPLMTAKSYGLSVDNLILGIGAALHYN
                     NSEDTQSVELQELIKSNGVKKAVAKIANISNDEELLNNIEKSYIFMKNL"
     regulatory      21488..21589
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            21772..22344
                     /locus_tag="KR294_001591"
     CDS             21772..22344
                     /locus_tag="KR294_001591"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HBH0239673.1"
                     /translation="MKALQEKILREGSVSGNDILKVDSFLNHQIDVAFLNEIGREFKE
                     RFKEEKVDKIFTIEASGIAIASIVSQYFDNAPVVFAKKSESKNLDKDVYETNVYSFTK
                     AREYSVKVSKKYINKGENILIVDDFLANGRAALGLKDLIEQAEANLVGVGIVIEKGFQ
                     AGGALLKANDVRLESLAVVESIDNGTVKFR"
     gene            22408..23058
                     /gene="fsa"
                     /locus_tag="KR294_001592"
     CDS             22408..23058
                     /gene="fsa"
                     /locus_tag="KR294_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HBH0239674.1"
                     /translation="MIFFIDTANIEEIKEANDLGVICGVTTNPSLIAKEGRDFIEVVK
                     EISEIVDGPISAEVISLEHEGMIEEAEKLSKIHKNIVIKIPMTAEGLKAVKVLSSKGI
                     KTNVTLIFSAGQALLAARAGATYVSPFVGRLDDISQNGLDLIEEIVDIFSVNSIEAQI
                     IVASVRNPIHVLQAARMGADIATVPLKVINQMIKHPLTDKGIDSFMKDWEGASLKL"
     gene            23210..26134
                     /locus_tag="KR294_001593"
     CDS             23210..26134
                     /locus_tag="KR294_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH0239675.1"
                     /translation="MDKILREIQREDKKNPYTDQELAEMLNVARSEVISVRKKNNILD
                     SRERRKKILIKDISKIVSENPQMSERKITEILIENGYNISRSAVSKLLKEENLNQSKI
                     GIKDKEPASSGKYVKVSKVVEEDGFEELIGIKGSLKEKVNLAKSAIMYPPNGLHTIIY
                     GETGVGKSELATCMYKYAIKNNIKEENSPFIVFNCADYAENPNLLIAQLFGVVKGAYT
                     GADANREGLVEQANNGILFLDEIHRLPAAGQEILFSLIDRGEFRRLGESSSNRKANVL
                     IISATTENPDSNLLQTFRRRIPMVINLPNMSERPKSERYEIIIKFFEREAKRVNKNFI
                     ITKEVMCALMNYKCTGNIGQLKSDIQVTCARAFSKSIFSSDKVIIDLDSLRDYIKSGY
                     YDCNCKNEKYSEFSVEDIYIDISELVSGKNRILSDNEISEIYNYAEKELKVLESKCFS
                     EEELKNAFIEKLDKKFNAIKNNKNLSDRRSRIDWGGQLKESTLEIMDKVIVFIKEQFK
                     HVNQGLYLALAIHIEHAIGRIKDGKTIINPSLDKIKASMPMEYELSRYIMGIVEDLTQ
                     VTFPEDELGYLAYYINKFCYNEESIKDKVKVVIVTHGKVGIEMSKVVNHILGIECTLG
                     IEIALTDSPSEGIEHVLEELQKIEARKGILVLIDMGSLVILGDEVEKRLGIRCKTVNR
                     VDTLLAMEAGKLATIEGKSLDGIIADLKKNKNYAMINTNKFSYRKNEYGKKNVIITLC
                     LSGVGTALNLKEHIEKQIKEYDTLIEVKPVAFLNNNLEEELNDIEAEYNIIAICGTID
                     IDYKNVPFISYNEVLGKNGINKVLEHLNSKQPVLNIENQLNNLIHEDLILYNFEGISK
                     EYIIDTLVSKLEEGGYVDSKYILSVYKREAMGSVVMASKVAVPHGLPENVIKPAIAIA
                     RLNKPIVWDNKFMVDLVVLLALKENNKKEIRSLFSKINDQHTLEVLLNTEDKNEIKEL
                     LS"
     gene            26711..27169
                     /locus_tag="KR294_001594"
     CDS             26711..27169
                     /locus_tag="KR294_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH0239676.1"
                     /translation="MEFINFVSDKVIDLKMDCKTKEDFFKEIHNKVFDLGFVKEEFGE
                     KILARENVFPTGLNLGDYGVAIPHTDAEYIKEQFISVCTFNEPVVFSSMEDQDEKVPV
                     NLAFVLGLNQPHSQLSVLTELMGIMQNKELVDKLMSSTDKEEVLKTLKSL"
     gene            27230..27505
                     /locus_tag="KR294_001595"
     CDS             27230..27505
                     /locus_tag="KR294_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH0239677.1"
                     /translation="MKKILVACGAGIATSTVVCDKVERLVKENNIQAEVIQCKIAECA
                     TKQEGADLIVSTTILPTTYNIPAIKATAYITGVNTAALDKKILDALK"
     gene            27564..28838
                     /locus_tag="KR294_001596"
     CDS             27564..28838
                     /locus_tag="KR294_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012951111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HBH0239678.1"
                     /translation="MDKLLAVVQYILNMGPTVILPITIVVLGMIFRIKFTKALKSGLT
                     IGIGFVGINLVVNLLTSTLGPAAQGMVERFGLNLTVIDVGWPTTASATWASPVAPILI
                     PVCLLVNLLLLYFNKTKILNVDIWNYWHFIVAGAVGYIVTGSYVWAIFCAILMELLVL
                     FIAEKTAKNVQEFYDLEGIALPTGSTASFAPLGYLVGKFVEKIPGINKIQADPDSIQK
                     RFGIFGEPMMMGIILGIILGALAGYDVAGIFNVGISMGAVMLLMPRMVRILMEGLIPI
                     SESIRDFLQAKYGDRELYIGLDAAVATGHPAVISTALILVPITLFLAVILPGNKVLPF
                     GDLATIPFYMAFIVCFRKGNIVQSVITGTIVIAISLYMATNFADVHTQLLQQANMMPE
                     GTTMVTSIDTGGNLLKWGILKLSQLVSSFGIF"
     gene            28968..30020
                     /locus_tag="KR294_001597"
     CDS             28968..30020
                     /locus_tag="KR294_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HBH0239679.1"
                     /translation="MKAAVLHGTNDMRFEDIEIKPCESDEVKIKVMAAGICGSDPPRV
                     LKHWKYPVPAIPGHEFSGVIAEVGKDVKNVKVGDRVVAIPFIPCNECEYCKRGLFSLC
                     DDHGMLGAKSFGAFAEYVNIKATNVLPIGDMNFEDAAMIEPLAVAMHGVLNIGVQVGD
                     TVAVMGSGTMGQLVIQGLKIAGAGTIIAVDISDNKLRESKELGADIIINAKDINPVEK
                     IKELTGGKGVDIALECAGSKITQEQCLLITKKKSKIGFLGIAYSDITLSEEAFENIFR
                     KELELKGFWNSYSAPFPGQEWTKGINLVNEGKIKLKEMVSHRFSLEDTYKAFEMIRDR
                     KEEFNKILILPQGVEK"
     gene            30020..31051
                     /locus_tag="KR294_001598"
     CDS             30020..31051
                     /locus_tag="KR294_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012986518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding dehydrogenase"
                     /protein_id="HBH0239680.1"
                     /translation="MKAVVKTKPGYDNVEVLEVEEPKATGDKVKIKVEYSGICGSDIH
                     SFKGEYANIKAPVTLGHEFSGIVVEVGEDVKNIKVGDRVTSETTFATCEKCIYCETKD
                     YNLCPTRKGIGTQVNGSFAEYVLSREESIHVLPENVSLLSAALTEPLACCVHAALEKT
                     TIESSDTVLIIGPGPIGLLLAQVVKSQGATVIMSGVTKDKERLEIAKNLGVDRTVNVM
                     EESLADVVNEMTDGNGVNKGFDCSGFMPAVNEALRLLRKKGTFVQVGIFAKKLNEMDQ
                     EAIIQRELQYIGSRSQKPSSWITALDLMANGKVNTEALVTRTVGLDEFKEGITALMNG
                     EEIKVAVKS"
     gene            31143..31955
                     /locus_tag="KR294_001599"
     CDS             31143..31955
                     /locus_tag="KR294_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HBH0239681.1"
                     /translation="MSTLRDHSNNIRKNIIKMVAEAKSGHPGGSLSIADMLTVLYFDK
                     MNVCAENPKMADRDRFVLSKGHAAPALYATLAEKGFFPEEELITLRKFGSKLQGHPDM
                     KKVAGIDMSTGSLGQGLSAANGMALAGKLDNKDYTVYTILGDGEIQEGQIWEAAMTAS
                     HYKLDNLIAFVDLNGLQIDGSNEEVMNVSPVDDKFKSFGWNVIVINGHSFEEIGNAVD
                     EAKKVTGKPTVIIAKTVKGKGVSFMENNAAWHGTAPNAEQAEQALKDLEGGL"
     gene            31958..32878
                     /locus_tag="KR294_001600"
     CDS             31958..32878
                     /locus_tag="KR294_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HBH0239682.1"
                     /translation="MGIATREAYGQVLKELAENKDIVVLDADLGKATKSISFKEVAPD
                     RFFDMGIAEGDMIGTAAGLATCGKIPFASTFAIFAAGRGYEQIRNSVAYPNLNVKIAA
                     THAGVTVGEDGGSHQAIEDISLMRGIPNMVVLNPADALEARQAILTSIDYNGPVYIRL
                     GRAATPDVNSENYKFEIGKGTVLREGSDITVIATGIMVAKALEAAEELAKEGINVEVV
                     NISTIKPLDEALIKETAKKTGKVVTAEEHSIIGGLGSAVCEALAETKDVVVRRIGVKD
                     VFGQSGTPADLLKHYGLTTEDIVKNIKELL"
     gene            33053..33499
                     /gene="rpiB"
                     /locus_tag="KR294_001601"
     CDS             33053..33499
                     /gene="rpiB"
                     /locus_tag="KR294_001601"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose 5-phosphate isomerase B"
                     /protein_id="HBH0239683.1"
                     /translation="MKISIGCDHGGYELKEYIKENLINKGIEVEDVGTNSKESVDFPI
                     YAKKVSQNVQSKKSDLGILCCGTGIGMSIAANKFKGIRAAVVSDCFSAKATREHNNTN
                     VLCLGERVIGKGLAMRIVEEWLNSSYNGERHARRLQMIDDIEKENL"
     gene            33529..34194
                     /locus_tag="KR294_001602"
     CDS             33529..34194
                     /locus_tag="KR294_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HBH0239684.1"
                     /translation="MSIICASIMCADQMKLKEELEALEEAGVKLLHCDVMDGIFVKNL
                     AMGPELLKSISENTTIPLDIHLATETPDKYIDMMSYIKPKYISFHVESSTNVKADIQK
                     LRNYGIGPVLAISPQTSVDKIEEYISLVEGILVMTVNPGFAGQKFNLSVLDKLDKLTE
                     ILKDYDNPPFIEVDGNINKDTIKLMNGKKVDIYVVGTSALFNDKPPISYKDKIEELKE
                     SIK"
     gene            34304..35806
                     /locus_tag="KR294_001603"
     CDS             34304..35806
                     /locus_tag="KR294_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HBH0239685.1"
                     /translation="MGDLYKLQNGTDIRGIAYENDSKEVNLTVEEVKKIAKAFHIWLK
                     EKTKKDKVTVAIGTDSRITGSQFRSTVIETLTNDDCNVIDCEIATTPAMFMTTIMDGY
                     NSDGAIMITASHLPYYYNGLKFFTESGGLEKTDIKEMLDIAVKNDSVDYEEVNKKGEV
                     IVKNLIEDYSNLLIDKIRKGVNSSKNYEKPFSGLKILVDAGNGAGGFFAEKVLHILGA
                     DTTGSQFLNPDGMFPNHIPNPENKEAMESICKAVLDNKSDLGIIFDTDVDRAAIVGKN
                     GKPINKNALIAVISSIVLEEHPKTAIVTDSITSEGLAKFINELQGRHHRFKRGYKNVI
                     NEAIRLNSEGEECHLAIETSGHAALKENYFLDDGAYLIAKILIKVAKLSLEGKTIEEL
                     IENLEEAQEEKEVRIGINKEDFRTYAEDILKDLDSHVKSIDGWSVAPNNFEGIRVNCD
                     ESNGDGWFLLRISLHEPLLALNIESNKIGGAEQIYSKLKLFLEKYDLKGL"
     gene            complement(36118..>37224)
                     /locus_tag="KR294_001604"
     CDS             complement(36118..>37224)
                     /locus_tag="KR294_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBH0239686.1"
                     /translation="IKYNNYNLKDMSITYVFFSNLLSMYNKKTINKKLAIVFLISIVV
                     QAIIQYLVLIFFMYIYYAEAIAIVILFTLVNTVFHFYIYNFLSVKFNYINNISKNIKN
                     IENGNLKYKLEVIGDDEISTLAKSINNITGGLETAVDANIKNERMKAELITNVSHDLK
                     TPLTSILSYVDMLKNNDFDRETINDYINILDKKSQRLKLLIDDIFEASKLSSGDVEFN
                     ITKTDIRELLIQSIVEFEDKIQNSSLDFIIETPEYAVFTMIDGKKTWRVFENLICNIL
                     KYSMPNTRVYIDMFIKEENIILTFKNISNDKLNLKPEELIERFRRGDISRKTDGSGLG
                     LSIAQNIIELENAHMEIIIDADLFKVMLTFRKVN"
BASE COUNT        14629 a         4200 c         6757 g        11638 t
ORIGIN      
        1 actatgagat atgtattgat ttcttctcca aagaacccca atatttgcag taattgcacg
       61 ttctaatggt attgaacaga gattttctgt attttgaaat atttctttat acaatattgt
      121 tgaagccaag tcattttcta gtaaataacg tatggtagaa agttgatttg agtgtaaaat
      181 tatatttggc ttagcttttt caagtctttt tgtaataatc ttatagtgat aagaaccttc
      241 agataagatt acaaaaggta cattttttaa catataattc gatataatag gatgttttgc
      301 caattcattt ttgggatttg taactaagta taattctgtt ttatagattg tctttgaatc
      361 tatatcatca taaatatcac tgtcaattat accaatacaa aaatcaagtg tagattcttc
      421 aatcatttta gctccaacaa atgttggaac ttcaaaaatt ttaagctcta tatctggata
      481 aattacatta aacctaggaa gtatttttga aagcaaaaac gtacctaaaa ctgtaggaat
      541 acctattttg agagaagctt ttctcttttt tcctaaatca agtgcgtcac attgaaaatc
      601 ctcaaattgt tttataaaat gttttgactt gtctaaaaaa atttttcctt caggcgttaa
      661 ctctatttta ttacctattc tgtaaaaaag ttcaaagcca agttcttttt ctaattcttt
      721 aattgctaat gttatggatg gttgagaaat atgaatactt tccgcagcct tagtcatgtt
      781 tttatattta cagacagttt gaaaatagta taaatagttt atattcattt ggtattagtt
      841 cctttcattt acatattagt gacaagtata taattaacaa tagcataagt tttgtatatt
      901 gttgtaaaaa aatagaatag ttttaaacta tcatagcata agtttttgat attttcaatc
      961 tattaagaat agtgctatta ttaaattaac aaaagagaat agctggtatg gtttagagta
     1021 aatcaatcta tattacagtt atatcaacga atatcaaaaa attatctatt aaaaaataaa
     1081 aattattttt acaattaaat tgttaattaa atcataaaga aaaaagtgat attaacaaga
     1141 taaaattttt ttaatcagaa atgttaattt aataacaaaa tagagtattg gggagaaagg
     1201 agaaatatat tttttaataa tatttgttaa tttaataacg aaaaatgaaa gggagtgatt
     1261 tagtgaagtt tgaattgatg gattttttaa tgaatccttt tgtccttatg tttgctgcag
     1321 taattacagg aattttattt ggaaaaatta aatttgggaa gtttaatttt ggggtatcag
     1381 gagcattatt tacaggatta tttattggat ggcttgcata tagcttgggg aatctaataa
     1441 tagcaaaagg ggaaacagca gcaggatata aggcagcaac tgtaatgatg gggaatggaa
     1501 ttatttcttc tgacttcttt gatttctttt taataatatt tgttgcagca gttggtctat
     1561 tggcagcaaa agatatgaaa gctgtattaa agaagtatgg agcaagattt gtaattttag
     1621 gagttcttat aacttttata ggtggctcta tgacttatgc aatgacttta ctatcaagtg
     1681 ataaaggaag tagtgcttat gaagtttctg gcgtttacac aggagcatta acaagttcgc
     1741 ctggattagc tgctgcttta gaaacagctg gtaaacatgc agaagatgta tcaaaagaat
     1801 ttgaaaaagc ttcaataaaa gataaaaaag aaattttaaa agtagtcgac ccagaaggca
     1861 aattggatgt gaatacaact acatcactga ctcaagagca aatagataag tatattgcat
     1921 atgctgaagc tggtgttggt ataggtcatg cagtcgcata tccttttgga gttttaatag
     1981 taatcttagg tgtaaatttc cttccaaaat tatttaggat ggacctaaaa gaagaaagaa
     2041 gaaaatatga gaaggaaatg aaggaagcaa gagatagtgt ttctggtaaa acgataccag
     2101 aagttccatt taatataata acatttttct tgacatgttt agctggatac ttagttggag
     2161 gaatacatgt atttatggga ccactagggt acttcacact aggtgcaaca ggaggttcac
     2221 taattgtatc tctagttctt ggatatatag gtaagatagg ggtagtaaat ttcagaatgg
     2281 aagaaaaggt tttaaatatt ttaaaacaaa tagggctagt gtttttctta gcaatagttg
     2341 gattaagata tggtggaaaa gtagttgatt caattatgac atctggtatg cacctagcct
     2401 tagtagcaat agcagtaggt gttacagcta tgatgatagg attcttagtt ggcaaatacg
     2461 tatttaaatt aaattggatt ttattatctg gagctgtctg tggtggtatg acatcaacac
     2521 caggtcttgg agctgctgtt gatgctcttg atagtgatga cccagcagca ggttatggtg
     2581 ctacgtatcc atttgcatta ttaactaaag ttatattggt tatagtttta cacaaacttc
     2641 caatgtaaat aagattttat atggggggat atttatgaat aatgaaggag catttgaaga
     2701 attaagtgga agattaagaa ataaagaatt gtgtgattta ataatgaatg cagatgaagc
     2761 tgctaaaatt atagaggatg gcatggttat tggagttagt ggatttacac cttcaggcta
     2821 tccaaaagca gtaccattag cagtttcaga aagagctaaa agtggagaaa agataaaatt
     2881 aaccgtatat tcaggagcat ctttaggtcc agaagttgat ggagcatggt cagaagcagg
     2941 tataattgaa agaagacttc cttatcaaac taattcaata cttagaaata atattaataa
     3001 aggtgttgtt gattatatag atatgcacct aagtcattct actcaatttt taaattatgg
     3061 aactatacct aaagtagatg tagctatagt agaagcactt gcaataactg aagaagggaa
     3121 tattatacca actagtggga taggtaattc tccatctttt ataaaaagtg cagataaagt
     3181 aatagtagag ataaatcttg caaaaccaat ggaaatggaa ggtatggcag atatatatat
     3241 tacggaaaat ccaccaaata gaaaaccaat agaaataaat catcctaagg atagaattgg
     3301 aacaacatat ataccttgtg gtttggataa aattgcagga gtagtaatta ccaatatgca
     3361 agataagacc cgtccattgg gggttgtaga tgaagcttcg aaaaaaatat caaataatat
     3421 tattgctttt ttaagagaag aagtaaagtc aggcagatta tcaaagaatt tacttcctct
     3481 tcaatctggt gtaggaagtg tagcaaatgc agtattatat ggattatgtg aatctgaatt
     3541 tgaaaattta acttgttata cagaggttgt acaggactct atgttggatt taataagaat
     3601 gggtaaagtt acaatggcat ctactacatc tgtaagtcca tctccagaag gattaataaa
     3661 atttgaaaaa gatattgatt tttttaagga taagattata ttaagacctc aagaaattag
     3721 taacaatcca gaaatagcca gaagaattgg tgtaattgca atgaacactg caattgaagt
     3781 tgatatttat ggaaatgtaa attctactca cataatgggg tcaaagatga tgaatggaat
     3841 tggtggttct ggtgattttg ctagaaatgg agcaataact atatttagta ctgagtcaat
     3901 tgcaaaaaat ggtgatatat catcaatagt acctatggta tctcacgtag accacactga
     3961 acatgatgta atggtaattg taacagaaca aggatatgct gatttaagag gtcttgcacc
     4021 tagagaaaga gctataaaaa taatagaaaa ttgtgcccat ccagattata aagaacaact
     4081 tagggattat ttaaatagag cttgtaaaag tggagcaaaa caaacacctc acatattgga
     4141 cgaagcttta tcatggcata gtaaatttat gagtacaggt acaatgaaaa aggctgaaac
     4201 ttttaaaagt gcattataaa atatttaata aattggaggt agattttaaa tggaaaaagc
     4261 agtggaaaac tttgaagatt taagtaagga atacattaat ggttatattg agagagcaag
     4321 aaaagctcaa agagagtttg aatgttatac tcaagaacaa gtagataaaa tagtaaaaat
     4381 agttggaaaa gtagtgtatt ataatgctga atatttagct aaacttgctg tagaagagac
     4441 tggaatggga gtatatgaag ataaggtagc taaaaataaa agcaaagcaa aagttatata
     4501 taacaattta aaagataaaa aatcagttgg tataattgat atagatagag aaactggaat
     4561 aacaaaggta gctaaaccag ttggagtagt agcggcaata actccttgta caaatccaat
     4621 cgttacacct atgagcaatg caatgtttgc acttaaggga agaaatgcaa ttattatcac
     4681 acctcatcat aaagcaattg gatgtagtac aaaaactgta gagatgatta atgaagaatt
     4741 agaaaaaata ggagctccag aaaatttaat acaaatactt gaccaacaat caagagaaaa
     4801 tacaagaaat ttaatttcat cagcagatgt agtaattgcc actggaggaa tgggaatggt
     4861 aaaagctgcg tactcaagtg gaaaaccagc acttggtgta ggggcaggaa atgttcaatg
     4921 tatcatagat agagatgtag acattaaaga agcagtacct aaaatcatag caggaagaat
     4981 ttttgataat ggtatcattt gttcaggtga acagtcagta atagtagcag aagaaatgtt
     5041 tgataaaata atggatgaat ttaaaaataa taaaggtttt atagttagag ataaagtaca
     5101 aaaagaagct ttcagaaatg ctatgtttgt aaataaatct atgaataaag atgcagtagg
     5161 tcaatcagtt catacaattg caaaaattgc aggtgttgag ataccagaag atacaaaaat
     5221 aatagtaata gaagctgatg gaccaggaga agaggatatt attgcaaaag aaaaaatgtg
     5281 tccagttata tctgcataca agtataaaag ttttgaagaa ggtgtagcta ttgcaaaagc
     5341 aaatttaaat gtagaaggaa aaggacatag tgtatctata cattcaaata cagttaaaaa
     5401 tatagaatat gcaggagaaa atatagaagt atcaagattt gttattaatc aatgttgtgc
     5461 tactagtgct ggaggaagtt tctttaatgg tcttgcacct actaatactc taggttgtgg
     5521 ttcttgggga aataacagca tctctgaaaa tcttgattat aagcatctaa ttaatatttc
     5581 tagaattgct tattatatgc cagaaaatga agtccctaca gatgaagaac tttggggata
     5641 aaatttagac aaaaaatatt cattctaaat taaagtagga atatatttta atttagaatg
     5701 aatttaagac ataaattaaa tttaaattag tttattggac taaatttaaa atattaagag
     5761 acatatagaa gaaggaagta ttataattta aaataaataa aaaaatctat aaaagagaag
     5821 gagtggtttt attatggcat taatgacagg agctcaatat attgaaagtt tgagaaaatt
     5881 aaatactaag gtttatatgt ttggtgaaga ggttaagaat tgggttgacc atcctatgat
     5941 tagaccatct ataaattgtg tagcagcaac ttatgactta gctcatgacc cagaatatgc
     6001 agatttaatg acagttactt caaatatcac aggtgaaaaa ataaatagat ttggtcatct
     6061 tcatcaaagt gttgatgatt tgataaaaaa agtaaaaatg caaagactat gtggtcaaaa
     6121 aacagcttct tgtttccaaa gatgtgttgg tatggatgcg tttaatgcag tgtattcaac
     6181 aacatttgag tgtgataaag cccatggaac taattatcat gataattttg taaaatactt
     6241 aacttatata caagaaaacg atttagtagt tgatggagct atgactgacc ctaagggaga
     6301 tagaagtcta tcacctagtg ctcaacctga cccagatatg ttccttcata tagtagaaag
     6361 aagagaagat gggataattg taagaggagc aaaggcacat caaactggtt caataaattc
     6421 acatgagcac cttataatgc ctactataag tatgactgaa gcagataaag actacgctgt
     6481 atcatttgca gttccttcag atgctgaagg agtgtttatg atttatggaa gacaatcttg
     6541 tgacactaga aaattagaag aaggtgcaga tgttgattta ggaaataagg agtttggagg
     6601 tcaagaagct ttagtagtat ttgataatgt atttgttcca aatgatagaa ttttcttatg
     6661 tggagaatgg gatttctctg gtatgttagt agagagattt gcaggatacc atagacaaag
     6721 ttatggtgga tgtaaagtag gagtaggtga tgtaataata ggagcagcag ctttagcagc
     6781 tgattataat ggagcaaaca aagcttcaca tataaaagat aaactaatag aaatgactca
     6841 ccttaatgaa agcttatatt gctgtggtat agcatgttca tcagaaggtc acaaaacaga
     6901 agctggaaac tatcaaatag atttacttct tgcaaatgtg tgtaaacaaa atgtaactag
     6961 atttccttat gaaatagtaa gacttgcaga agatatagct ggagggctta tggttactat
     7021 gccttcagaa aaagacttta aatcagacct taaagttgga acaagtggaa tgactattgg
     7081 cgaagtatgt aacaagtatt ttaaagcttc ttcagtggct tcaacagaag aaagaatgag
     7141 aatattaaga ttcttagaaa atatatgcct tggttcatct gctgttggtt atagaactga
     7201 gtcaatgcat ggggcaggtt caccacaagc tcaaagaata atgatttcaa gacaaggaaa
     7261 cataaatcaa aagaaagaat tagctaagaa aattgcggga ataaaaaaag aggaagcttt
     7321 aaatttataa aaagttgata tataaaggga aattatatat taatgtgtat taattaatga
     7381 aaaaatatgt agtataagag atagttataa aattatggtg gtttttagct aagtaaagaa
     7441 atttttaata aggagaattt acacatgacc tgtggagtta gattttgtgg gggctgtaac
     7501 cctagatacg aaagagggaa ggctcttaca ataatcaaag agcacttcaa tggtagggta
     7561 gattttagta tagcacaaga gaacgtcgag tatgatttgc tacttataat tggaggatgc
     7621 gcaactctat gcgcatccta tcaacaatat aaagtgaaaa atgaatgtgt taagatgtgg
     7681 gattttagcc atatagaaag agttataaat gtgattgaat cagcaatttg tgaaacttaa
     7741 aaaagctaaa tggggggatt tcattgagtt ggcaagaatt gtatcaaagt aaattatgta
     7801 gtgctacaga agctgtaaaa cagattaaaa acggtgatac tgtagtattt gcacattgtg
     7861 taggtgaacc tcctgcacta gtagaggcta tgattgaaaa tgctgaacaa tataaagatg
     7921 ttgagattaa acatatggta agcttgggta gtggtggata tactgctaag ggaatggaag
     7981 ctcattttag agtaaatcca atgtttgtaa gtggaaatgt aagaaaggca attgaaaatg
     8041 gagatggtga ttttacacct gcattcttcc atgaagtacc aaagttgctt agagaaaaaa
     8101 gattaaaatg tgatgttgtt ttagcacagg taactccacc agatgaacat gggtattgta
     8161 gcttaggaac atcagttgat tatacttatg aagccattaa aactgctaga acagtaattg
     8221 ttcaagtgaa tgaccagttt cctagaacct atggtgaggt agtccatgta tcagagtttg
     8281 actatatagt ggaaaaatca caacctttat ttgaactaca acctgcaaag attggagaag
     8341 tagaagaagc aattggtaaa aattgtgctt cattaattga agatggttct actttacagc
     8401 tagggattgg tgggatacca gatgcagtta tgttattttt aactgataaa aaggatttag
     8461 ggattcattc agaaatgatt tcagatggga ctttggccct ttatgaaaaa ggtgttataa
     8521 atggtaaata taaaaatttt gataaagaaa aaatgacagt taccttctta atgggtacta
     8581 aaaaattata tgactttgca aataataacc ctgcagtaga ggtaaaacca gtagactatg
     8641 tgaatcatcc agcaattata atgaaacaac ataagatggt ttctataaat tctgctatac
     8701 aagttgattt aatgggacag gtagttgcag aggctatggg acttagacaa tttagtggtg
     8761 ttggaggtca agttgacttt atacgtggag tgtctatggg tgaagatgga aaggcaatta
     8821 tagctatgcc ttcaataact acgaaaaaag atggtacagt aatttcaaaa atcgtgtcta
     8881 ttgtggatga aggtgcacct ataacgacat caagaaatga tgttgactat attgtaacag
     8941 aatacggtat agcagaatta aaaggaaaat ctcttagaga aagagcgaga aatttaataa
     9001 atatagctca tccaagtgta agagaaagtc tagcagtaga atttgaaaag agatttaagg
     9061 agaaatatta ataatagagg ggtgttaata atggaagcac ttagagtagt tccaaagata
     9121 ttttactttg atacatttaa agaatttaat gaagaattta aaataggaaa aaatgattta
     9181 gtaattacta atgagtttat atatgagcca tatatgaaac ctcttggaat agatacaaat
     9241 ttaatttttc aagaaaagtt tggaacaggt gaaccatctg atgaaatgat agactccatg
     9301 acaaaggaaa tgaagaaata caattttgat agaattattg catttggagg aggaacaata
     9361 gttgatatat gtaagatatt agcacttgat gttccagaaa agtctattga tttatttgaa
     9421 ggagaagtat cacctaaaaa agtaaaagag ttagtagtag ttcctacaac atgtggtaca
     9481 ggtagtgaag taacaaatgt agctattgca gagttaaaat ctaaacatac taaaaagggg
     9541 cttgcagtag aagaaacata tgcagactat gcagtgttaa ttccagagac agtaaaaggg
     9601 ttaccttaca aattctttgt tacaagttcg gtagatgctc ttatacatgc tattgagtct
     9661 tatctttctc caaaagcaag tccatttaca gagatgtatt ctctacaagc aataaaaatg
     9721 attatggatg ggtataagaa gatagttgat aaaggagaag aagagagatt taatcatctt
     9781 agagactttg tacttgcatc aaattatgca ggaattgctt ttggaaatgc tggttgtgca
     9841 gcagttcatg cactatctta ttcaataggt ggagctttcc atgttgcaca tggtgaagca
     9901 aattatcagt tctttactga agtatttaag atgtattcta gaaaaaaacc taatggaaaa
     9961 attataaaat gtacaaaaat tttagcagat gcccttgaat gtgaccctaa ctgtgatgtt
    10021 tatggagaat tagaaaagtt tttaaataaa ttaatagcta aaaaagcttt gagagaatat
    10081 ggaatggtgg aaagtcagat agatgaattt acagatagta caatagcaaa tcaacaacga
    10141 ctacttgcta ataattatgt agagcttagt agagaggaaa taagagagat atttgcaaat
    10201 ctttattaat acaatttttt atttatatgt atagtcaaca taaacaatgc taattatatt
    10261 tatgtacaaa taaaaataag ggaacttaaa ttttaattaa agttaagttc tcttattttt
    10321 atatggagtt aaatataagt atatttttaa tttaaaatat gcttatattt aagtctatta
    10381 ctttatttga aacaatttgt agaatttcaa attccttgac agtaataagt aagtaattgt
    10441 ataatcaaac tgcaatatat taataatatt agtgaaaatg aaaggattat aaaatatgta
    10501 taaatcagta aatttttcaa aaaaatctgt attaataaat tcatttttaa gtaaattttt
    10561 aaaaataatt ggatggggtt tggtaagctt atttacatta tcagccttag tactttcaac
    10621 tatttccatt ataattggat gggctgtaat acttcctatt caagtatgtg cagtattttt
    10681 acttatagga ggagtttgta tttttaaagg taagagatta ggagaccaaa tttctcgtta
    10741 taaaaaatat tgtacaatta taaacaatag aaatattatt ccagtagaac ttattgcaga
    10801 aaacacatct aaatcattaa attttataat aaaagatgta caaaagatga tagacaaaaa
    10861 ctactttata aatacttata ttgataaaag aaataatcag attgtgttaa caaatgaaga
    10921 ttttgttcca ccaagatatg aagatgtagc atatgaagtc aaagaagaag aaaagactga
    10981 tgaatccaat gaagttgata caattataaa taaaggaatg aattatctaa cacaaataaa
    11041 agaagctaat aaaaatatta aatcagaatc aatgggcgat aaaattgtac aagtagaaga
    11101 tgttacaagt aaaatatttg atgttgtaaa acatgaccca tcaaaactta ctcaaataca
    11161 aaaatttatg gattattatc ttccaaccac tttaaaacta ttaaattcat atcatacatt
    11221 ggaagaacaa ggaattgata gagaaaatat aacaacaact atggaaagta ttgaaaatac
    11281 aatgaatacg attgtagtag cttttgaaaa tcaattggac tatctgtttg aagatgaagc
    11341 cattgatatt tctacagata ttactgtttt agagaatatg ttagtccaag aaggattaac
    11401 gagtggtaaa ttttaacttc aatagaaaaa atattctgtt atttttaaac aattaattag
    11461 tcataaagta taaaatgtgt attatataag ttaatcagta ctttatgaag gaagaggaga
    11521 gaaagataca atgaataatt tagatgatat accagttatg ccaactttga cacttgaccc
    11581 atttggagaa gaatcaaaca ctaatgatat agataattct gacttattaa tgaaaaagga
    11641 tgaaaaagac ccagaagaag aaaaactgtc tgaatctgaa cgcaagatgg taaaggaatt
    11701 tgcggaaaaa atagatatta caaatacaaa tatgattttg caatatggag ctggtgctca
    11761 aaaaaaggta gcaagttttt ctgaaacagc tttaaagagt gtaaagacaa gagatttagg
    11821 agaagttgga gatatgctta caaatctagt tactgattta aaagcatttt cagcagatga
    11881 aaaagaacaa agtggttttt taggaatttt taaaaaggca aataataaaa tttcaaattt
    11941 aaaaactaag tatgatagtg cagaggtaaa tgtggataaa gtaagcaaag agcttcaaaa
    12001 gcatcaggtt aaaatattga aagatatagc aatgcttgat aagatgtatg aattgaactt
    12061 agcttactca aaagagctta ctatgtatat tatagcagga aaacaaaaat taaaggatat
    12121 gaaagaatat gagatgccaa agttgagaga aaaagctcgt ttatctggtt caacagaaga
    12181 tgctcaatct gtaaatgata tggtttcact ttgtgacaga tttgaaaaga agattcatga
    12241 cttagaatta actagaatgg tatcgcttca aatggctcct cagataagat tggttcaaaa
    12301 tagtaataat ctgatggcag aaaagattca atcaactata gtaaatacca ttccattatg
    12361 gaaaaatcaa atagtgcttg ctcttggaat ttctcactta aatcaagcta tgaaagcaca
    12421 gcgtgaagtt agtaatatga caaatgagct tttattaaag aatgcagaaa ctttgaagat
    12481 gggaacaata gaaacagcaa aagaatcaga aagaggaatt gtagatatag acacaattaa
    12541 gaaaactaat caatctctaa tatctactat tgatgaggta gttaagatac aacatgatgg
    12601 tagaataaag agacaagaag cagaagttga attatcaaaa atagaaaatg aacttaaaag
    12661 caagcttctt gaatttacag ttaaataaaa attatactaa gataaaaaga gactgtctca
    12721 aaattggata tgtccctgtc aagtagacag acttaaaaaa ggctatcttt actcggaatg
    12781 agttcgatat tcaatcggac tcattccgtt ttttaattgt attctttcat tattataaaa
    12841 ataaatataa tcatttatta gactaatcat ttcctttgga tctgtagtat caattaaata
    12901 tattaattca gatttaaaat gactgaaaaa actttctata ggagcattat cccagcagtt
    12961 gccccttcgg gacattgatt gtataatacc attatcctta agccttttag agtaagatct
    13021 acttgtatat tgtgaacctt gatctgtatg taaaatacaa tctttagcta aattcatatt
    13081 tattagttga tttactgtat tattaactaa tttagtatcc atttttgtac ttatctcata
    13141 tgccactatt tcaccattaa ataaatcttt ggctacattc atatataaga attttttacc
    13201 gataggtatg tatgttatat ccatacaaat tttttctaat ggttgattag ctctaaattc
    13261 acgatttaat atattatcat atatctcata tgatttaaac ttacgtctat atactttctt
    13321 tctaataata gatttaatac ctagttcttt catcaaccta tatactctct tatgattaat
    13381 aggggtatca agtattttat ttaaataagt acaaattctt tttctaccat aagttcctct
    13441 atatttttta tgtatttcaa ttatataatc cttaataatt ctatctttga tacccctatc
    13501 ggaagatttt ttagaataac ttagccattt atagtaaccg cttcttgaca cacttatcaa
    13561 cttacacata ctagaaatac tatacttcct agacagaagt ttaattgttt taaatttatc
    13621 gcttactttg acttgtccaa tagggtactt aactttttta agaattcatt ctccatgcgt
    13681 aagtacttca attcttcttc aacagattta aattttctat tatcattttc tagactaata
    13741 tttttaaatc tgcccctagt ttcatcatca aatgcagttt tgcctttatt tttataatct
    13801 tttacccagt tttgaacttg tgttttgctt cttatattca gcatctcagc aattttgtat
    13861 gatgagtatc cttcttttat atataagttt acagctttta gcttaagttc tttgctatat
    13921 tttttgtgtt ttttagacat agaaaaaccc ccttagagta tacgcttttt agacctatta
    13981 taatagcctt ttatttaaat gtctactata aggggattat actaaaatag agataagtct
    14041 ctttttcatt gtttaaatga ttaaagtata tttatattat aaatttctat tatcttttaa
    14101 cataacatca tgagctccac cttcaactat actagtagaa gatacaagtg taagtttagc
    14161 atttttttga agttcaggaa tgctaagtgc tccacagtta cacatagtag aacgaacttt
    14221 acttaaagaa agagttacat tgtctttcaa agaaccagca taaggaacat aagagtcaac
    14281 accttcttca aaagaaagtt tcttatctcc accaaggtca tatctttgcc agtttctagc
    14341 acgagcagaa ccttctcccc aatactcttt catataacta ccatttatat taactttgtt
    14401 agttggactc tcatcaaaac gagagaagta tctaccaagc attataaaat ctgcacccat
    14461 agctaaagct aaagttatat gatggtcata aacgatacca ccatcagaac aaattggaat
    14521 ataaatacct gttttttcaa agtattcgtc cctagcttga gcaacttcaa ttatagaagt
    14581 agcttgtcca cgtcctatac ctttttgttc acgagttata catatagaac caccaccaat
    14641 accaacttta acgaagtcag caccagcttc agctaggtaa aggaatccct cacggtcaac
    14701 tacatttcca gctcctacct taactgtatc accatatttt tcacgaatga aatcaagtgt
    14761 tattttttgc cactcagaaa aaccttctga agaatctata cataaaacat cagcaccagc
    14821 ttcaactaaa gcaggaacac gttcagcaaa gtctctggta ttaataccag ctccaactac
    14881 atatctctta gaagaatcta aaagttcaag tggattttct ttatgagaag agtaatcttt
    14941 acggaatacc atatacataa gattaccatt gtcatcaagt acaggaagag aattaagttt
    15001 gtggtcccat ataatgttgt ttgcttcctt taaagtaaca tctttgttag cataaactat
    15061 agatgacata ggagtcataa attcactaac tttagtatct aaatccatac gacttatacg
    15121 ataatcacga cttgcaacaa tacctaataa tttaccagtt gaagttccat cttcagtaac
    15181 agctactgta gaatgtccag ttttttcttt taagtcaagt atgtctttta atgtgttatc
    15241 aggtttaata tttgaatcac ttacaacaaa accagctttg tgggatttaa cacgtgctac
    15301 catagcagct tcatcttcaa tagtttgaga accgtatata aatgaaatac caccttcttt
    15361 agcaagtgca atagccattt tgtcatcaga aacagattgc ataatagcag aagtcaaagg
    15421 tatattcata taaatatctg cttcctcgcc ctttttaaat ttagtaacag gtgtttttaa
    15481 acttacatta gcaggtatac aatcagtaga agagaaacct ggtacaagaa ggtattcact
    15541 gaaagtatgt gatggtgtat caaaataaaa cgccattttt taatcactcc ttatattttt
    15601 atacttttta taattgatag tattaattat aacttattct ttaattttat taaagtattt
    15661 tgtcaaatat tgagattttt gaaaaattta aactatttta attgaatttg tttaatatat
    15721 attgccttat agggtaaagt tgtatattaa ataatgttta gtgtttaata gtagctaatt
    15781 tgaaattaat ctttagttat tcatataatt acatttgtat agtttatatt gataatattg
    15841 ctagagagtg cataaacctc aaaaatacag ataaattaaa tctatattag tatatccaaa
    15901 agtacattta ataaatttat ttaactgaat tattattttc atttctatta aatttaaata
    15961 ttttataaaa atagtattat ttacaaaatc atatactcca aaatactaca taaataaaat
    16021 taaacaaaaa ctaaaatgac aaatgtcatt atctaaagtg acatagaaac ggtttcttaa
    16081 agttgttact ataaaatata aactctataa taaaagtata acaaaaggga atcatatcga
    16141 tatagaatat aattcaagag gaggtaaaat tatgagtagt tctaatcaat cgacaataaa
    16201 gacatctata cagcgagtag ggaaattttt aagtggtatg gtaatgccaa atataggagc
    16261 ttttatagca tggggtctta taacagcatt atttatacca acaggatgga tgcctaatga
    16321 aaaattgagt actataggcg acccaatgat aaaatacctt ttaccactat tgatagctta
    16381 tactggtggt aaagcaatag caggacaaag aggtggcgta ataggtgcag cagcagctat
    16441 gggagtaatt gttggggcag atataccaat gtttatcgga gcaatgataa tgggaccatt
    16501 tgcaggatgg gtaattaaga agttcgataa atttgtagat ggaaagatac caacaggatt
    16561 tgaaatgtta gtaaataact tttcaatagg tataataggt atgcttcttg caatactagg
    16621 attttatgca attggaccag caatagtagc agggacagct cttatagaat ctggagttca
    16681 atttatagtt agcaaaagtt tattgccttt agtttcagta tttatagaac ctggaaaagt
    16741 attattctta aacaatgcaa taaatcatgg tatattaggg cctataggta tagctgaggc
    16801 aaaagaagca ggtaaatcta taatgttctt actagaaagt aaccctggac caggtttagg
    16861 agttctatta gcatattgga tgtttagtag aggaagtgta aaacaatcag caccaggagc
    16921 tgtaataata catttctttg gtggtatcca tgaaatttac ttcccatata ttttaatgaa
    16981 tccagtttta atattggcta caatggcagg tggagcagca ggaatattga ctttttcaat
    17041 attaggagct gggcttgtag cagcaccatc accaggaagt atatttgcac ttatggcact
    17101 agctccaaag ggaggattac ttccagtatt agcaggggtt gcagtggcaa cagttgtatc
    17161 attcttagtg gcagcaccat ttgttaagag agcttcagca aatgaaagtg aagaagacag
    17221 tacttcttta gaagaagcta aagcaaaaat gagtgatatg aaatctgcaa gtaagaactc
    17281 tgagaaaaat attgagaaaa aacagcttga agtaaatgag attaagaaga ttgtatttgc
    17341 atgtgatgca ggaatgggtt cgagtgcaat gggagcttct agatttaaaa atagaataaa
    17401 aaacttagat ttagatatag aaattacaaa ttcatctgtt gataatcttc cagatgatac
    17461 acaaatagta gtaactcaca atacattagt tgaaagagtt gctaagaaca attcaagtgt
    17521 tgagatagtt tcaataaaca attttttaaa tgacccaaat ttagatacat tatttaaaag
    17581 attagaatct aaataaaaat aaaaagtacc actaattagg agtggataat ttgaaaaaaa
    17641 agaagattac atctaggcaa aaaaagataa tactaatgat agtagaaaat tcaaagaaaa
    17701 acattccaat aactatttct gagattgcag ggacgttaga gttaagttca agaactgtac
    17761 ttagagatat gtctggaatt gaaaaatggt ttgatgaaaa tgattttaac tttgtaaaaa
    17821 aaccaggagt aggattgatt ttagaggaaa atatagaaaa tcaaaacttt ataattgagt
    17881 tgttagaaga agaaaaaata gaaaaagaat acagcaagga agaaagaaat ttaattatat
    17941 tatcaaagct actagtttct aacgagccag taaaatctta ttattttgca aaaatattaa
    18001 aggtatctga aggggtactg aataatgatt tttcattagc aagtaaatgg ttggaaagat
    18061 ttgatattga gcttgttaga aaaccagggc ttggtgtcta cctaaaaggt caagaaaaaa
    18121 gctttagaga ggcatatgta aatcttatat acgattcatt caatgaaaaa gaaatactag
    18181 atatggtcag aaatataagt gaaaatatac aaacagataa agcaatagaa attttaagtg
    18241 aaaatagact tttaaattta atggataggt gcataataat aaaagttgaa gctacattaa
    18301 caaagaagct ttcagattta gatgtaaatt tagctgatag tgcatatata gggcttgtag
    18361 ttcatatttc attagcctta cagaggataa aaaatggtga aaatataact atggataaag
    18421 agtttctaaa agaattatct ataacagaag agtttaaatt agctaaagaa atcgtaaaag
    18481 gtatggaaac agattttaac atggatatac cagtagatga ggttggatat ataactatgc
    18541 atataagagg tgcaaagcaa aggtcatctt caaatcataa ggctttaaac ttggatgata
    18601 tagaaataat ggaaattaca aataagatga tagatttggc tgaagatgaa tttaaaataa
    18661 gtttaaaaaa tgacgagagg ttatttaaag acctagcaaa tcacttagga ccttctataa
    18721 atagattgaa tatgggatta gaaataagaa atcctctttt agatgaaata aaaagcaagt
    18781 attcatatgc ctatgatgga gttgaaaaaa tttctagaat tataaaagat aaactaaata
    18841 taaattcaat acctgaatca gaaataggat atattgcaat gcactttgca tcagccatag
    18901 aaaaaaatct tatgatgaat actaatataa atattgttgt ggcatgtccc actggaatag
    18961 gtacttcaag attcttatca actaagattg aaaataaatt tcctaattta aatatacttg
    19021 aaaccatatc agctataaac atagatgaag agtatttaaa gggaaaagat gttgatttaa
    19081 tagtgtctac agttgagtta aatacaagtt taaattatat atgtgtaggt ccatttatga
    19141 gtttagatga tgaacagata atcaaggaaa aaataaaatc tatagctcaa aataaattaa
    19201 ttaatttaaa tacaaaaaat gatactaaaa gtaagaataa agtatatgaa cagataacag
    19261 aaagtatgaa tataggaaaa gatattcttc aatttttaga ggaaattaga tttgaaaaat
    19321 ttgaaagtaa agatttaagt gagcttattg aagactcatc aaaaatattt gcaaaatcta
    19381 gtgaagatat aatgtctata aaagaatcgt taaaagaaag attaaaaatc tcaattccat
    19441 atatagaaga atcaaaaatt ctattattac attgtatgag tgaaagaata gatattatga
    19501 agttatcaat aataaaactg gagaatcgaa tcgtgctaga ttcaaatgaa gaaatcgaca
    19561 atgtagtttt tatgttactt cctaaaaatt caccaagtta tcaaagacaa ataatgagtg
    19621 aaataagtgg ttcattaata gacaatataa tttttactaa taagataaat aaattctcta
    19681 tagaagagat gacattagag gtaaaagata tagtttttaa tttttataca aacagattaa
    19741 aagcatttat agatgaataa aattaatatt aaaaaggaag gttgatacta tgagtaaagt
    19801 attgaatgag aataatatat ttttagggtt agatagtgtt tcaaaggaag aagctataac
    19861 tttagcagga agaaaattag ttgaaaatgg atatgtaaaa gaagaatata taccagcaat
    19921 gctagaaaga gaaaaagtaa tgactacata tatgggaatg ggagttgcta ttccacatgg
    19981 tgtaaatgaa gcaaaaaaag aaatattatc ttctggaata gttatactac aattccctaa
    20041 tggtatagat tttgatggag aaaaagcata cttattaata ggaatagctg gtgttggaga
    20101 tgaacattta gaaatactat ctaatatagc agtagtttta gatgatgact taacagaaag
    20161 actaaaaaat tcaaatgaca aacaagcttt tatggaagct tttgccaaat aatcttagga
    20221 gggatttaaa atgaaaaagg caatccagtt tggagcagga aatattggaa gaggttttat
    20281 tggaggcttg ttagttaagt cgggttatca tgtagtattt gctgatgtaa atgaggagat
    20341 attaaactca ataaataaag ataaaaagta tactatacac ataagagatg tagaatgtat
    20401 agatgaagta attgataata taagtgcggt ttcatctata aaagaagaaa taatagatga
    20461 gattgtacag gctgaaataa taactacagc agttggacct ttagttttga ctaaaatagc
    20521 ctctacaatt gcaaaaggta taaaggctag aaaagaaaag ggtttaacaa gtaatctaaa
    20581 tataatagcc tgtgaaaatg caatatacgc aagttcttct ttaaaagaag aggtacttaa
    20641 gtatttaaat aaggaagaag tagaatattt agagatatat gttggttttc caaactgttc
    20701 agttgataga atagttcctc ctggtaaaaa tgaaaatcct cttgatgtaa cagttgaaaa
    20761 tttttatgag tggaatgttg aaaaacaagg atttaaaggg gaaataccaa ctatagttgg
    20821 aatgaattta gctgacaacc ttatggctta tatagagcgt aaattgttta cactgaatac
    20881 aggtcatgct ataacagctt atataggata tttaaaagga tataagacta tagaagagag
    20941 tataaaagat aaatttatct gtgatatagt caaaagtgca atggtagaaa gtggagaagg
    21001 attgattaaa aaatacaatt ttgactcaga agcgcactat aaatatattg ataaaatttt
    21061 aaatagattt aaaaatccat atcttaatga tgatgtatta agagttggaa gggaaccatt
    21121 aagaaaacta agtgataaag atagattgat taaaccttta atgacagcaa aatcatatgg
    21181 attatcagtt gacaatttga ttcttggaat aggtgcagcg cttcattata ataatagtga
    21241 agatactcaa agtgtagaat tacaagagtt gataaagtct aatggtgtaa aaaaagctgt
    21301 tgctaaaata gctaatataa gcaatgacga agaactttta aataatatcg aaaaaagtta
    21361 tatatttatg aaaaatttat aaatttactt gaaaaaaagt agttctgata aagtaactat
    21421 aatatattat tctacacagt ttgaattatt tgttgaataa tagagaatta taatatataa
    21481 ttaaaaggaa taaattaata tatttacctg tatatgtttg ataatatggt tcaaatgttt
    21541 ctactaagct accattaata gcttgactac aggagtgaag aagatatagt ttatacttat
    21601 tttaaattat atattaagtt aattactttg aattttaagc tcctgtctat gatatagaca
    21661 ggagcttttt tagtatttta atataaaata cttacaagaa tagatagcaa aattagaaca
    21721 aatataattt ttttattaat ataactttag aaagggctag gtggaagttc aatgaaggct
    21781 ttacaagaaa agatattgag agaaggcagt gtttcaggaa atgatatact aaaagttgat
    21841 agttttttaa accatcaaat tgatgtagct tttttaaatg aaataggaag agaatttaaa
    21901 gagagattta aagaagaaaa ggtggataag atatttacaa tagaggcttc aggaatagct
    21961 atagcatcaa ttgtttcaca gtattttgat aatgcacctg tagtatttgc aaaaaaatca
    22021 gaatctaaaa atttggataa agatgtatat gagactaatg tatattcatt tactaaggca
    22081 agagaatatt cagttaaagt ttctaaaaag tacataaaca aaggtgaaaa tatattgata
    22141 gtggatgatt ttttggcaaa tggaagagct gctcttggac ttaaagattt aattgagcaa
    22201 gcagaagcta atttagttgg agtaggaatt gtcattgaaa aaggatttca agctggagga
    22261 gcacttttaa aggctaatga tgtaagatta gagtctttgg cggtagttga atctatagat
    22321 aatggaactg taaaatttag gtaatttatg atattatata cttgtgttta gcacatattt
    22381 taactatgta attatggagg attttttatg atatttttta tagacacagc caatattgaa
    22441 gaaataaaag aagcaaatga tttaggtgta atatgtggtg taactactaa tccatctcta
    22501 atagctaaag aaggtagaga ttttatagag gtagttaaag aaataagtga aatagtagat
    22561 ggaccaataa gtgcagaagt aataagttta gagcatgaag gtatgataga ggaagcagaa
    22621 aaattatcta agatacataa aaatatagtt ataaagatac ctatgacagc agaaggtcta
    22681 aaagcggtga aagtactatc aagtaaaggt ataaaaacta atgtaacact tatattctct
    22741 gctggacaag ctcttttagc tgctagagct ggagctacat atgtaagtcc ttttgttggt
    22801 agattggatg atatatcaca aaatggtctt gatttaattg aagaaatcgt tgatatattt
    22861 agtgtaaata gtattgaggc tcaaataata gttgctagtg ttagaaatcc aatacatgtt
    22921 ttacaagctg ctagaatggg agcagatata gcaacagttc ctcttaaagt tataaaccaa
    22981 atgattaagc atcctttgac agacaaagga atagatagct ttatgaagga ttgggaaggt
    23041 gcttctttaa aattataatt ataaactacg ctttataagt atattaaaga ggttattatg
    23101 gaaattctaa gtaataaggc taggctattt tgcctagtct tattttggtg tataatatat
    23161 tgaaacatat tattgaaata gattaatttt ttaagtgagg aggcgaaaaa tggataaaat
    23221 attaagagag atacaaagag aagataaaaa aaatccatat actgaccaag aacttgctga
    23281 aatgttaaat gtagctaggt ctgaagtgat atcagtgagg aaaaaaaata atattttaga
    23341 ttcgagagaa agaagaaaaa aaatattaat aaaagatata tcaaaaattg taagtgaaaa
    23401 tcctcaaatg tctgaaagaa aaataactga gatattaata gagaatggat ataatatatc
    23461 gagaagtgca gtttcaaaat tattaaaaga agaaaattta aatcagtcaa agattgggat
    23521 taaagataaa gagccagcat catcaggaaa gtatgtgaag gtgagtaaag ttgtagaaga
    23581 agatggattt gaagaattga taggtataaa gggaagtttg aaagaaaagg taaatctagc
    23641 taagtcagca ataatgtatc ctcctaatgg ccttcatact ataatatatg gagaaacagg
    23701 ggtaggtaaa agtgaattag ctacatgtat gtataaatat gctataaaaa acaacatcaa
    23761 agaagagaac agcccattta tagtgtttaa ctgtgcagac tatgcagaaa atcctaatct
    23821 attgatagct caactctttg gggtagtaaa aggtgcatat acaggagctg atgcaaatag
    23881 agaaggtctt gtagaacaag ctaataatgg aatattgttt ttagatgaaa ttcatagatt
    23941 gcctgctgct gggcaagaaa tcttattttc attaatagat agaggagaat ttagaaggtt
    24001 aggagaaagt agttctaata gaaaggcaaa tgttctcata ataagtgcta caacagaaaa
    24061 cccagattct aatttacttc aaacatttag aagacgtata ccaatggtaa taaatttacc
    24121 taatatgagt gaaagaccaa aatctgaaag atatgaaata ataataaagt tttttgaaag
    24181 agaagcaaag cgagtaaaca agaattttat aataactaaa gaagttatgt gtgcacttat
    24241 gaattataag tgtactggaa atataggtca gttaaagagt gatatacaag taacttgtgc
    24301 tagagctttt agtaaatcaa tattttctag cgataaggta attatagatt tagatagttt
    24361 aagggattat ataaaaagtg gatattatga ttgtaattgt aaaaatgaaa agtattctga
    24421 gttttcagtt gaggatatat atatagatat cagtgaattg gtgagtggaa aaaatagaat
    24481 tttatctgat aatgagataa gcgagatata taattatgca gaaaaagagc ttaaggtttt
    24541 ggaaagtaag tgtttttcag aagaagagtt aaaaaatgca tttatagaaa agttagataa
    24601 gaagtttaat gctattaaaa acaataaaaa tttatctgat agaagaagtc gaatagactg
    24661 gggaggacaa ttaaaagagt ctacattgga gataatggat aaggtaattg tatttattaa
    24721 ggagcagttt aagcatgtaa atcaaggatt gtacttggct ctagcaattc acattgagca
    24781 tgctataggt aggataaaag atggaaaaac tataataaat ccgagtttag ataaaataaa
    24841 agcatcaatg ccaatggaat atgaattgtc aagatatata atgggtatag tggaagattt
    24901 gacacaagta acatttccag aagatgaact tggatatttg gcttattata taaataaatt
    24961 ttgttataat gaggaaagta taaaagataa agttaaagta gtaatagtta cgcatggtaa
    25021 agttggaatt gaaatgtcta aagttgtaaa tcatatttta ggtatagaat gtacactagg
    25081 tatagaaata gcacttacag attcaccatc agaggggata gagcatgtat tagaagagct
    25141 tcaaaagata gaagctagaa aaggtattct agttctaatt gatatgggtt ctttggtaat
    25201 tcttggtgat gaggttgaaa aaagacttgg aattagatgt aaaactgtaa acagagtaga
    25261 tacgttattg gcaatggaag caggaaaact tgcaaccatt gaaggaaaaa gtttagatgg
    25321 tataatagca gatttaaaga aaaataagaa ttatgccatg ataaatacaa ataaatttag
    25381 ttacagaaaa aacgagtatg gaaagaaaaa tgtaatcatt actttatgtt tgagtggtgt
    25441 aggtacagct ttaaatttaa aagagcatat agaaaaacaa attaaggaat atgacacttt
    25501 aattgaggta aagccagttg cttttttaaa taataattta gaagaagagt taaatgatat
    25561 tgaagctgaa tataatatta ttgctatctg tggaactatc gatatagatt ataaaaacgt
    25621 accttttatt tcttataatg aggtacttgg taaaaatggt attaataaag tattagagca
    25681 tttaaacagt aaacaaccag ttttaaatat tgaaaaccag ttgaataatt taatacatga
    25741 agatttgatt ttatacaatt ttgaaggaat ttcaaaggag tatataattg atactcttgt
    25801 ttcaaagctt gaagaaggtg gatatgttga ctcaaagtat atattaagtg tatataaaag
    25861 agaagcaatg ggaagtgttg taatggcctc taaggtagcc gtgccacatg gacttccaga
    25921 aaacgttata aagcctgcaa tagcaatcgc aaggttgaat aagcctatag tgtgggacaa
    25981 taaatttatg gtggatttgg tagtactact ggcacttaaa gaaaataata agaaagaaat
    26041 acgaagctta ttttcaaaga ttaatgacca acatacttta gaagttttat taaatactga
    26101 agataaaaat gaaataaaag aacttttaag ctaattatta gtacagagaa gaaagacaaa
    26161 aaatttgctt tagtataaaa tttaaaacta cttaattgct aagtagttaa ttactcgata
    26221 taaggctagt tctatgaaat ttatttatat gattttatag aattagcttt tttcttggta
    26281 aataaaatat atgaatttat ttatgcaaaa agtaaatttt attggacaat tctatgagaa
    26341 tttttcctat atttcttata aaatatagaa tatataaaaa taaattaaat tcataataaa
    26401 taattttata aaatagttgt taaacataaa aaaccatttg taaaaaacaa aaaaatcatt
    26461 tctctaacaa aaaaaaccac aaaaaatata aaaaagtatg gctagttaag tgattaacaa
    26521 gtaaaaatta aaataaaaat caaaaaaaat ttatcaatga aagtcagcta aaatcctgga
    26581 agagagcatt atttttggga aaacattttc ttttgtttca caaaaaaagc cactttttgg
    26641 cacacaacat gctttatata aagtcaagaa aaactaaggt ataagacaaa ggcaattagg
    26701 aggtgtaaat atggagttta taaattttgt aagtgataaa gttatagacc ttaaaatgga
    26761 ttgtaaaacg aaagaagatt tctttaaaga aatacataat aaagtttttg atttaggctt
    26821 tgtaaaagaa gaatttggag aaaaaatatt agcaagagaa aatgtatttc caacaggttt
    26881 aaatttagga gattatggag tagcaatacc acatacagat gcagaatata ttaaagagca
    26941 atttatatca gtctgtactt ttaatgaacc agtagtgttt agttctatgg aagaccaaga
    27001 tgaaaaagta cctgtaaatt tggctttcgt attaggactt aatcaaccac acagtcaatt
    27061 atctgtatta acagaattaa tgggaattat gcaaaataaa gagttagttg ataagttgat
    27121 gagttctact gataaagaag aagttttaaa gacactaaag tctttataaa aataaaaaag
    27181 tactaaaaat aaaaaatata aaaataaaaa ttattaggag gaaataaaaa tgaaaaaaat
    27241 attagtagca tgtggagcag gaatagcaac atcaacagta gtttgtgaca aggtagagag
    27301 attagttaag gaaaataata tacaagcaga agttatacaa tgcaaaatag ctgaatgtgc
    27361 aacaaagcaa gaaggagcag atttaatagt atcaacaact atactaccaa caacttataa
    27421 tataccagca ataaaagcaa cagcatatat aactggagta aatacagcag cattagataa
    27481 aaaaatatta gatgctttaa aataatccta tcatagatac attgaaataa tattttataa
    27541 aacagaaaaa ggaggattta taaatggata aattattagc agtagtacaa tacattttaa
    27601 atatgggacc gacagtaata ctaccaataa caattgtagt actaggaatg atatttagaa
    27661 ttaagtttac aaaagcttta aagtcaggtc ttacaattgg tataggattt gtgggtataa
    27721 acttagttgt aaacctatta acatcaacac tagggccagc ggctcaagga atggttgaaa
    27781 gattcggact taatttaaca gtaatagatg ttggttggcc aacaacagca tcagcaacat
    27841 gggcttcacc agttgcacca atattaatac cagtttgttt attagtaaac ttactattat
    27901 tatacttcaa taaaacaaag atattaaacg ttgatatatg gaattattgg cactttatag
    27961 tagcaggtgc agttggatat atagtaacag gaagttatgt ttgggctata ttctgtgcaa
    28021 tactaatgga gttattagta ctgtttattg cagaaaagac agcaaaaaat gttcaggagt
    28081 tttatgattt agaaggtata gcattaccaa ctggttcaac agcttcattt gctccacttg
    28141 gatatttagt aggtaaattt gttgaaaaaa taccaggaat aaataaaata caagcagacc
    28201 cagactctat acaaaaaaga tttggtatat ttggagaacc aatgatgatg gggattatac
    28261 taggtataat acttggagca cttgcgggat atgatgtagc aggaatattc aatgtaggta
    28321 tatcaatggg tgcagtaatg ttacttatgc ctagaatggt tagaatatta atggaaggtt
    28381 taattccaat ttcagaatca ataagagatt tcttacaagc aaaatatgga gacagagaac
    28441 tttatatagg tctggatgca gcagtagcaa ctggacatcc agcagttata tcaacagctc
    28501 ttatacttgt tcctataact ttgttcttag cagttatact accaggaaac aaagttttac
    28561 catttggaga cttagcgaca ataccatttt atatggcatt tatagtgtgt tttagaaaag
    28621 gtaatatagt tcaatcagtt ataacaggaa caatagtaat agctatatca ctttatatgg
    28681 ctacaaactt tgcagatgtt catacacaat tattacaaca agcaaatatg atgccagaag
    28741 gaacaacaat ggttacaagt atagatacag gtggaaactt gctaaaatgg ggaatattga
    28801 aattatctca attagtttct tcatttggaa tattctagta tgtagttaat agagattact
    28861 cttttttagt aaagtatgcg aaaatttaac atttagcagc tactaaaaaa gagtaatatt
    28921 ttttataaat ttttaaaaat acaaaataca agaggaggag atttatcgtg aaagcagcag
    28981 tattacatgg cacaaatgat atgagatttg aagatataga aataaaacca tgtgaaagtg
    29041 atgaagtaaa aataaaagtt atggcagcag gaatatgtgg gtcagatcct ccaagagtat
    29101 taaaacattg gaaatatcca gttccagcta taccaggaca tgagttttct ggagtaattg
    29161 ctgaagttgg taaggatgta aaaaatgtaa aagttggaga tagagtagtt gcaattcctt
    29221 ttataccttg taatgaatgt gaatattgta aaagaggatt attttcattg tgtgatgacc
    29281 atggaatgtt aggagctaaa agttttggag cttttgcaga gtatgtaaat ataaaagcta
    29341 caaatgtact tccaatagga gatatgaact ttgaagatgc tgcaatgata gagccactag
    29401 cagttgctat gcatggagta cttaatatag gtgttcaagt tggagacact gtagctgtaa
    29461 tgggtagtgg aacaatgggg cagttggtaa tacaaggact taaaatagca ggggcaggaa
    29521 caattatagc agttgatata tctgataata aattaagaga atcaaaggaa ttaggggctg
    29581 atataataat taatgctaaa gatattaacc cagtagaaaa aataaaagaa cttactggtg
    29641 gaaaaggtgt tgacatagct cttgaatgtg caggttcaaa aataactcaa gaacaatgtt
    29701 tacttataac taaaaagaaa agtaagatag gatttttagg gatagcatat tcagatataa
    29761 ctttatcaga agaagcattt gaaaatatat ttagaaaaga actagaatta aaaggttttt
    29821 ggaactctta ttctgcacca tttccaggac aagaatggac taagggaatc aatctagtta
    29881 atgaaggaaa gataaaatta aaagaaatgg tatctcatag attctcactt gaagatactt
    29941 acaaagcatt tgaaatgata agagatagaa aagaagaatt taacaaaata ttaattttac
    30001 cacaaggggt tgaaaaataa tgaaagcagt agttaaaact aaaccaggct atgataatgt
    30061 agaagtttta gaagtagaag aaccaaaagc tacaggagac aaggttaaaa taaaagtaga
    30121 atatagtggt atatgtggtt cagatataca ttcatttaaa ggtgaatatg caaatataaa
    30181 agccccagta acattaggtc atgaattttc tggaattgtt gtagaagtag gagaagatgt
    30241 taaaaatata aaagtagggg atagagttac atcagagact acttttgcaa cttgtgagaa
    30301 atgtatatat tgtgaaacta aagattataa cttatgccca actagaaaag gtattggtac
    30361 tcaagtaaat ggaagttttg ctgagtatgt attatcaaga gaagaaagca tacatgtact
    30421 tcctgaaaat gtatctttat tatcagcagc ccttacagag ccactagctt gttgtgttca
    30481 tgcagctctt gaaaagacta ctatagaaag ttctgataca gttttaataa taggaccagg
    30541 accaattggt ttattattag ctcaagttgt taaatctcaa ggtgctacag ttataatgtc
    30601 tggtgttaca aaagataagg aaagattaga aatagctaaa aatcttggag tagatagaac
    30661 tgtaaatgta atggaagaaa gtttggcaga tgtagtgaat gaaatgactg atggaaatgg
    30721 agtaaacaaa ggatttgatt gttctgggtt tatgccagca gttaacgaag ccttaagact
    30781 gcttagaaaa aaaggtactt tcgtacaagt tggaatcttt gctaaaaaat taaatgaaat
    30841 ggaccaagaa gcaataatcc aaagagagtt acaatatata ggaagcaggt ctcaaaagcc
    30901 aagttcttgg attacagcat tagatttaat ggcaaatggg aaagtaaata cagaagcttt
    30961 agttactaga actgttggtt tagacgaatt taaagaaggt attacagctt taatgaacgg
    31021 ggaagaaata aaagtagcag taaaatctta aaaaaacatt tgtattattt taaaaaaaat
    31081 tgtaaaatct actgtaggat aaaaaaatgt aaggtcttaa aaaataacag gaggaagaaa
    31141 gtatgagcac tcttagagat cattctaata atattagaaa aaacataata aaaatggttg
    31201 cagaagctaa aagcggacat ccaggtggtt cattatcaat agctgatatg ttgacagtat
    31261 tatattttga taagatgaac gtatgtgcag aaaatccaaa aatggctgat agagatagat
    31321 ttgttctatc aaaaggtcat gcagcaccag ctttatatgc tacattagca gaaaaaggat
    31381 ttttcccaga agaagaatta ataacactaa gaaaatttgg ttctaagtta caaggtcacc
    31441 cagacatgaa aaaagtagca ggaatcgata tgtctactgg ttctcttggt caagggctat
    31501 ctgcagcaaa tggtatggca cttgcaggaa aattagataa caaagactat acagtatata
    31561 ctatattagg tgatggagaa atccaagaag gtcaaatatg ggaagctgca atgacagcat
    31621 cacattacaa attagataat ttaattgcat ttgttgactt aaatggatta caaatagatg
    31681 gttctaatga agaagtaatg aatgtaagtc cagtagatga caaattcaaa tcttttggat
    31741 ggaatgtaat agtaataaat ggacattctt ttgaagaaat aggaaatgca gttgatgaag
    31801 ctaaaaaagt tacaggaaaa ccaactgtaa taatagctaa aacagtaaaa ggtaaaggtg
    31861 tttcatttat ggaaaataat gctgcatggc atggaacagc tccaaatgca gaacaagcag
    31921 agcaagcatt gaaagattta gaaggaggtc tataggaatg ggaatagcaa ctagagaagc
    31981 ttacggacaa gtgttaaaag aacttgcaga aaataaagat atagtagtat tagatgcaga
    32041 tttaggaaaa gctacaaaaa gtatatcatt taaagaagtt gccccagata gattttttga
    32101 catggggata gcagaaggtg acatgattgg tacagcagca ggtcttgcta cttgtggaaa
    32161 aatacctttt gcgagtactt ttgcaatatt tgcagcagga agaggctatg agcaaataag
    32221 aaactctgta gcatatccaa atttaaatgt aaaaatagca gctactcatg caggtgtaac
    32281 agtaggtgaa gatggtggta gccatcaagc tatagaggat atatctctaa tgagaggtat
    32341 accaaatatg gttgtattaa atccagcaga tgctttagaa gcaagacaag ctattcttac
    32401 atctattgat tataatggac ctgtttatat aagattaggt agagctgcaa ctcctgatgt
    32461 aaacagtgaa aattataaat ttgaaatagg aaaaggaact gttttaagag aaggttctga
    32521 cataacagta atagctacag gaataatggt agcaaaagcc ttagaagcag cagaagaact
    32581 tgctaaagaa ggtataaatg tagaagttgt taatatatct acaataaaac cattagatga
    32641 agcattaata aaagaaactg ctaagaaaac tggaaaagta gttacagcag aggagcacag
    32701 tataataggt ggtttaggtt cagctgtatg tgaagcttta gcagaaacta aagatgtagt
    32761 agttagaaga attggtgtta aagatgtatt tggtcaatca ggtacaccag ctgatttatt
    32821 aaaacactat ggtttaacta cagaagatat agtaaaaaat ataaaagagt tgttatagat
    32881 ataaatatat ctaaataaca aattgatttg acataagtca attaaagctg tcttaaaaat
    32941 agaaagaaat ttctacaatg ggacagcttt atttttacaa tactttattt ttatgataat
    33001 tataaaatag tctgaaagta atcaaaaaaa ttataaaaag aggtgctatt taatgaaaat
    33061 atctattgga tgtgaccatg gtggttatga attaaaggaa tatataaagg aaaatttaat
    33121 aaataaaggt atagaagttg aagatgtggg tacaaattca aaagaaagtg tagattttcc
    33181 aatatatgca aaaaaggtaa gtcaaaatgt tcaaagtaaa aaatctgatt taggcatact
    33241 ttgttgtgga acaggaatag gtatgtctat tgcagcaaat aagtttaaag gaatcagagc
    33301 agctgttgtt tctgactgtt tttcagctaa ggcaactaga gaacacaata atacaaatgt
    33361 actttgttta ggagaaagag ttattgggaa aggattagca atgagaattg ttgaagaatg
    33421 gttaaattca agttataatg gagaaagaca tgcaagaaga ttacaaatga ttgatgatat
    33481 agaaaaagaa aatttataaa tatataattt acaacaaggg ggagcgttat gtctattatt
    33541 tgtgcttcaa taatgtgtgc agaccaaatg aagttaaaag aggaattaga agctcttgaa
    33601 gaagcaggtg taaaattact tcattgtgat gttatggatg gaatatttgt taaaaacttg
    33661 gctatgggac cagagttatt aaaatcaata agtgaaaata caacaatacc tttagacata
    33721 cacttagcca cagaaactcc agataaatat attgatatga tgtcttatat aaagccaaaa
    33781 tatatttctt ttcatgtaga atcaagtaca aatgtaaaag ctgatataca aaagttaaga
    33841 aattatggta tagggccagt gttagcaata agccctcaaa caagtgtgga taaaatagaa
    33901 gaatatataa gtttagttga gggtatctta gtaatgacag taaatccagg gtttgcaggt
    33961 caaaagttta atctttctgt attggataag ttggataaac ttacagagat actaaaagat
    34021 tatgataatc ctccatttat agaggttgat ggaaatataa ataaggatac tattaaactt
    34081 atgaatggta aaaaagtaga tatatatgtt gttggtactt cagctttatt taatgataag
    34141 cctccaattt catataaaga taaaatagaa gaactaaaag aaagtataaa gtaaccatgt
    34201 aataaaatta taatatgttt ctgtttaata gtaaaaattt aggtggaaac aagaaatttt
    34261 ataatattta ataaaaattt tggttgagta aggagaattt tttatgggag acctatataa
    34321 actacaaaat ggtactgata ttagaggaat agcgtatgaa aatgattcta aagaagttaa
    34381 cctaactgta gaagaagtaa aaaaaatagc taaagcgttt catatttggt taaaagaaaa
    34441 gactaagaaa gataaagtaa ctgttgccat aggaactgat tctaggataa caggaagcca
    34501 atttagaagt actgttattg aaactttaac taatgatgat tgtaatgtaa ttgattgtga
    34561 gattgccaca actccagcta tgtttatgac aactattatg gatggataca attctgatgg
    34621 ggcgattatg attacagcaa gtcacttacc ttattactat aatggtttaa agtttttcac
    34681 agaaagtgga ggtttagaaa aaactgatat aaaagagatg ttggatatag ctgttaaaaa
    34741 tgatagtgta gactatgagg aagtaaataa aaaaggtgaa gttatagtaa aaaatttaat
    34801 agaagattat tctaatttat tgatagataa aattagaaaa ggtgtaaatt caagtaaaaa
    34861 ttatgaaaag cctttttctg ggcttaagat attggttgat gcaggaaatg gggctggtgg
    34921 attctttgct gaaaaagttt tacacatact gggagcagat acgacaggta gtcagttttt
    34981 gaacccagat ggtatgttcc caaatcatat acctaatccc gaaaacaaag aagcaatgga
    35041 aagcatatgt aaagctgtgt tggataataa gagcgaccta ggaataatct ttgatacaga
    35101 tgtagacaga gctgctattg taggtaaaaa tggcaaacca ataaataaaa atgctcttat
    35161 agctgttata tcatcaatag tattagaaga acatccaaaa acagctatag taacagattc
    35221 gattacttct gaaggacttg ctaaatttat aaatgaatta caaggaagac atcatagatt
    35281 taaaagagga tataaaaatg taataaatga agctataaga ttaaatagtg aaggtgaaga
    35341 gtgccattta gctatagaaa cgtctggaca tgctgcttta aaagaaaatt atttcttaga
    35401 tgatggggca tatttaatag ctaaaatttt aataaaagta gcaaagctat ccttggaagg
    35461 aaagactata gaagaattga tagaaaacct tgaagaagct caagaagaga aagaagttag
    35521 aataggcatt aataaagaag attttagaac atatgcagag gatatattaa aagatttaga
    35581 ttctcatgtt aagagtattg atggatggtc tgtagcacca aataattttg aaggcataag
    35641 agttaattgt gatgaatcaa atggagatgg atggttttta cttagaatat cactacatga
    35701 accattatta gctttaaata ttgaatcaaa taaaattggc ggagcagaac aaatttattc
    35761 taagttaaaa cttttcttag aaaaatatga tttaaaaggt ctttagggta aatagaaaga
    35821 atatatttat attgaagaat aaatgtaaat ttgtacctaa gattacaaat attacaaaat
    35881 tgtaatctta ggtaacagag atgtaactga ttatggaaac actatgtgat attatagata
    35941 cagagagatg aaatatgtga tgaattatag agaaatataa tttaaaatgt attaatatca
    36001 caccaaaaag gtataatcaa aaaatatgta aatataaacc ccaacattta gaaaaagacc
    36061 tctaaggagg tttttttctt gtttaaataa cttaaaatat atttttatat taatatatca
    36121 attaactttt ctaaaagtaa gcattacctt aaataaatca gcatctataa ttatttccat
    36181 gtgtgcattt tctaattcaa ttatattttg agcaattgat aaaccaagac cagagccatc
    36241 tgtttttcta gatatatcac cccttctaaa tctttctatt aactcttctg gttttagatt
    36301 tagtttatca tttgaaatat ttttaaacgt taatattata ttttcttcct ttataaacat
    36361 atctatatag accctagtgt taggcataga gtattttagt atattgcaaa ttagattctc
    36421 aaaaactctc caagtttttt taccatctat catggtaaaa acagcatatt caggtgtttc
    36481 tattataaaa tctaaactgc tattttgaat tttgtcttca aattctacaa tactttgaat
    36541 taaaagttct cttatatcgg tttttgttat attaaattct acatctccac tacttagctt
    36601 agatgcttca aatatgtcat ctattaataa ttttaatctt tgtgattttt tatctaaaat
    36661 atttatatag tcatttatag tctctctgtc aaagtcatta ttttttaaca tatcaacata
    36721 gcttaatata gatgtaagtg gagtttttaa gtcatgagat acgtttgtga taagctctgc
    36781 cttcatcctt tcatttttta tattagcatc tacagcagtt tcaagaccgc ctgttatatt
    36841 atttatactt ttggctaaag tagatatttc atcatctcct ataacttcta atttatactt
    36901 taaattgcca ttttctatat tttttatatt ttttgatatg ttatttatgt aattaaactt
    36961 aacagataaa aagttgtata tataaaaatg aaaaactgtg tttacaagtg taaataaaat
    37021 tactatagct attgcctcag cataatatat atacataaag aatatcaaaa caagatattg
    37081 gataatagct tgtacaacta tagatattaa aaatactata gctaattttt tatttatagt
    37141 ttttttatta tacatactaa gtaagtttga aaagaataca tatgttatag acatatcttt
    37201 tagattatag ttattatatt taat
//
LOCUS       DAEPKC010000031        36666 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.031, whole genome shotgun sequence.
ACCESSION   DAEPKC010000031 DAEPKC010000000
VERSION     DAEPKC010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 36666)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36666)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36666
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.031"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            8..784
                     /locus_tag="KR294_001605"
     CDS             8..784
                     /locus_tag="KR294_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HBH0239687.1"
                     /translation="MEYIIFDLEFNQGFDKKLNKTVSNEKCPFEIIQIGAIKLDSKFN
                     IIDTFNSYVKPTIYKDIHPFISRMTNIKNSDFNDSPTFPEVYNNFIKFISSQDPILCV
                     WGAGDLKELYRNINYHKLPSNSLPKSYINIQQHASKYFNNPAGKSIGLQNAISILELD
                     EKMSYHNALNDAYYTAKVFIKIYNPSIVPDIYLYTSIKPKTIRYSNKKRVDYDKLFDE
                     FRKILNRELTKDEKKIINLAYNMGKTNQFTLENVKQRKNK"
     gene            complement(876..1628)
                     /gene="xth"
                     /locus_tag="KR294_001606"
     CDS             complement(876..1628)
                     /gene="xth"
                     /locus_tag="KR294_001606"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HBH0239688.1"
                     /translation="MKFISWNVNGIRACVGKGFLDFFKEVDADIFCLQETKLQEGQIE
                     LDLPGYFQYWNYAERKGYSGTAIFTKKEPLKVMYGINIEEHDKEGRVITLEFEDFYFV
                     TVYTPNSQSELKRLEYRTRWEDDFIDYLTKLDNHKPVIVCGDMNVAHKEIDLKNPKNN
                     MKNAGFTKEEREKFSKLLDSGFIDTYRYFNPDKEGVYSWWSYRFNARKNNAGWRIDYF
                     CASKKLEDRLVSADIHTEILGSDHCPVELEIK"
     gene            complement(1789..2739)
                     /gene="galT"
                     /locus_tag="KR294_001607"
     CDS             complement(1789..2739)
                     /gene="galT"
                     /locus_tag="KR294_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-1-phosphate uridylyltransferase"
                     /protein_id="HBH0239689.1"
                     /translation="MKELRIDPITNDVVIFATDRLKRPLDTADIPNEDEETNEYDEEC
                     PFCKGNEAHATDALFEIESEEGWLVKSVYNKFPIIDDMARDVYGVHEVMIESDKHNRS
                     FYNMSQKEFEDVFFMYRNRFRDLSKDDKVEYVSIFKNFLRKAGASLMHPHAQILSMSF
                     IPPEITNELLVSKEYYDSNKSSLYDDLIENEISLDRRVVYNGEAFLVLIPYATKYSGE
                     VRIIFKDKIEFGELNDNNIQELSTIFEKLFKKLYNINGYMPFNLCIHTHPTKIETKSY
                     FNVHMHIIPRKYNFGGFELGTNMYVSSMSPEDLTKKLKID"
     gene            3124..4320
                     /locus_tag="KR294_001608"
     CDS             3124..4320
                     /locus_tag="KR294_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBH0239690.1"
                     /translation="MNYSNRVSAMQASPIRKLVPFAQAAKDKGIKVYHLNIGQPDIKT
                     PKGFFDAVKNFDSEVLEYATSEGIPELLEALQNYYKTYDMNFEKDELLVTNGGSEALL
                     FTMMAVCDPGDNLLVPEPFYTNYNGFGQSVNVEVNAVTTKAENGFHLPSKEEILSKVD
                     DKTKAIILSNPGNPTGAIYTKEELNILAEIAKEKDLWIIADEVYREFVYDGLEYTSCG
                     NLEGVQDRVIIIDSVSKRYSACGARIGSIACKNKGLIAQILKLCQGRLCVPTLEQIGA
                     VELYKTPVSYFKEVNEEYKKRRDVLYNELMKVEGVICKKPTGAFYIVAKLPVENAEDF
                     TIWMLKEFNKDNETVMVCPAEGFYATPGLGRDEIRLAYILNEKDLHRAATLLKEGLEQ
                     YVALQK"
     gene            complement(4432..5772)
                     /locus_tag="KR294_001609"
     CDS             complement(4432..5772)
                     /locus_tag="KR294_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HBH0239691.1"
                     /translation="MKKRYNIAIVGGGSTWTPGLLKSLCKMSDRFPLNKVTMLDVVEE
                     RQRLIGEFGKILFKEEYPKATLEYTTNPDEAFIDVDFVFVQMRTGGLKMRELDEKIPL
                     QFGLVGQETCGAGGFAYGLRSIGDMIEMVKTVRKYSPKAWILNYTNPAAIVAEALKRV
                     FPDDKRLLNMCDQPVNLLRSYGRLLDMDSRTFEPVYFGLNHFGWFTHLYDKNGEDLVP
                     KIKDLVANSGFQPVDAEQRDKSWLDTYGMVKDMLEDVPDYLPNTYVQYYLYPDKKVAK
                     SNINCTRAREVMNGREKRVFEECKSVIEKGTSIGSNLVHNDAHGEFIVEVAEAIAHNK
                     HQIAIVITENNGAISNLPDDAMVEVAAILTKNGPRPLHVGNIPTFYKGLLEGQLAYEK
                     LAVDAYFEQSYEKAILSLTLNRTIISPTKARQVLDALIKVNKDYWPTLYKENEK"
     gene            complement(5911..6663)
                     /locus_tag="KR294_001610"
     CDS             complement(5911..6663)
                     /locus_tag="KR294_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBH0239692.1"
                     /translation="MNLIDKLDINQKKLSTNEISLLNYFLKNSEKINQKKIKDIANET
                     FNSTAYIVRFCQKLGFSGYSEFKNFLVFSYSNRNERNKEFTKSQSDIFTDVMDTQNLI
                     NVENIDMCLNEIHNSKHIYFFGVGSSRLVCTEMSQRFSAIGVNVKYYDDSTLMYLAAS
                     NITKDDLVIAVSMSGETAQVIKACNIAKTNQVKVISLTNISVNSLSNIADIKLFVSSP
                     QYNFNSVNYTSRVPALSLMEYMFHKYIEKYNR"
     gene            complement(6811..8388)
                     /locus_tag="KR294_001611"
     CDS             complement(6811..8388)
                     /locus_tag="KR294_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBH0239693.1"
                     /translation="MKQKMKGFFLQLGKSFLLPIALISAAGIFLGISSAFSNPNIVSD
                     MPFLANNFIQGILGFTKAITGVLFGNLAIFFAISISVGLAKEEKAVSAFSGFVGYLVL
                     HTSVNYMLGCRGIIAEPDMMREMGQAVTLGIQTLELGVFGGIVVGIITASLHNKYYNI
                     KLPDYLGFFGGTRFVPIITTVVFSILGIIIPYIWPYVNTIIQSVGIGIASLGYLGTFV
                     FGFLERLLIPFGLHHILNAMFRFTEVGGSLVVGGQEVFGALNIFLAQLSDPETISFST
                     EATRFLAQGKIPIMVFGLPAAAYAMYKTAKPENRSKVKGILLAGALATFVTGITEPLE
                     FSFLFVSPILFVIHAFLSGISFMMMHIFGVAIGNTQGGIIDLVVFGVMQPNTKWIYSI
                     ILGLVYAIVYYNVFKILILRFNLQTPGREEITDINFDLKPLSNKVEIAQSGETTKRAL
                     SIIKYLGGKDNIEDITNCITRLRVVVKDMSKVDENAFKKYTGAMGVIKVSDKDIQIIY
                     GPSVSQVRDEVSFAMSI"
     gene            complement(8800..9252)
                     /locus_tag="KR294_001612"
     CDS             complement(8800..9252)
                     /locus_tag="KR294_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBH0239694.1"
                     /translation="MNYIVKDTISFLVKTFPKIYSSLYLEDLKKFAPDYNVNKTQLRA
                     LVFIKNYGVISMTDLCSKLNIEKGSLTSMVDDLTDKKYVTRKRDLVDRRKYLIDITEE
                     GDKIATDFMDKLSDGLGEKLSKLTEEDRKKYLEAINTLQYILNKEEFR"
     gene            complement(9563..11008)
                     /locus_tag="KR294_001613"
     CDS             complement(9563..11008)
                     /locus_tag="KR294_001613"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HBH0239695.1"
                     /translation="MIDNKYTTYSNPLTDRYCSKDMSYIFSPQFKFSTWRRLWVALAE
                     GEHELGINITEEQLDELRANIDNINFDEARKIEKEVRHDVMSHVKAYGLQCEKAKGII
                     HLGATSAYVGDNTDVIQMNEALKLLRVKLVNLINNLKEFALKYKDMPALGFTHFQAAQ
                     LTTVGKRACLWAQDLILDLEDLNYRIDNMKLRGVKGTTGTQASFLSLFEGDHEKVKEL
                     DKKICKKMGYHSSYAVSGQTYTRKLDYQVISILSGIAQSMHKMTNDIRLLQSLKELEE
                     PFEKNQIGSSAMAYKRNPMRSERIASLSKYIISESISPAMVQATQWLERTLDDSANKR
                     LAIPQAFMAADAILEIGINVTDGLVVYENMINRRVNEELPFMATETILMEAVKRGGDR
                     QELHEIIREYSMKAAYRVKHEGKDNNLIELIMNDDSFKMSKEEILSIMDPKNFIGRAP
                     EQVVEFVNEVVEPAIKDYKEDLGKVDVDLRV"
     gene            complement(11152..12060)
                     /locus_tag="KR294_001614"
     CDS             complement(11152..12060)
                     /locus_tag="KR294_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBH0239696.1"
                     /translation="MYSTKILDDYEYETFNVFSTKLNPNTKHDYLSKVILFKEFLKGK
                     ELIYATKEDCKNFVDYIQTKYAKSTCEKIYSYLHSFYNFLKKEGYIDINPFRYVEKPT
                     VTRIKTKDDVLSIQEINKLIGILPKLNIRDRVIIVCLVTTGCLLNELVSLKWKDLMVD
                     ENDNSYVRLGKGRKERVVKLHPYFFKLLEDYRNYSGLPEVIIPSDDFIFTTQKSNSIT
                     DRNVRLIVKKALDLAGLSQYSARDFRHSFAAISLRLGADESDVKNQLGWSDKYYAIRY
                     KYVLNFVDSEIVDYLIEKDNLDINKK"
     gene            12317..13141
                     /locus_tag="KR294_001615"
     CDS             12317..13141
                     /locus_tag="KR294_001615"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HBH0239697.1"
                     /translation="METFSLLEIFKAVILGIVQGITEWLPVSSTGHMILVDEFIKLNF
                     SNTFISTFLVVIQFGSILAVLVIFFRKLNPFDSAKNIKQKKETVRLWLKVIIAVIPSG
                     VIGILFEDDIDRLFFNSTVVAIALIVYGIIMIGLEKRNKKPKYKDFSQVTYKLALCIG
                     LFQCLALIPGTSRSGSTIIGAVLLGTSRYVAAEFSFFLAIPTMLGASALKLLKAGFGF
                     TGFEWLILGVGSVVAFVVSIVVIKFFMDYIKKHDFKVFGYYRIVLGIVVLAYFFLL"
     gene            13181..13711
                     /gene="lepB"
                     /locus_tag="KR294_001616"
     CDS             13181..13711
                     /gene="lepB"
                     /locus_tag="KR294_001616"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBH0239698.1"
                     /translation="MSVKKEIFDWIKSIAMAIVLAFVILQFIRPSIVSGESMYPTLDD
                     KDYLILNRISYKVGKPEKGDIVVFKTNLVDGETGKKKDLIKRVIATEGDRIKISNSKV
                     YVNGKLLNEPYIHNNYTSGDIDTVVPKGKLFAMGDNRENSNDSRFPDVGMVDEDEVLG
                     KVMVRLLPLDNIGKVD"
     gene            complement(13793..15574)
                     /locus_tag="KR294_001617"
     CDS             complement(13793..15574)
                     /locus_tag="KR294_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UvrD-helicase domain-containing protein"
                     /protein_id="HBH0239699.1"
                     /translation="MSQYININSQLDALKLKEFEKIFYENINEDVKVVPKVTPFKGIN
                     TDLLYVKDGRILFIKFMDTTEDIFFILEEELLEVMNEEYELLKLKMGQKNRNISYNYV
                     YIMPYVEVEETYEFEEFVNNNIIDKNKLQDIMNKGSLEEYLNDENDEINLNLFLLDIC
                     SEYYIINDKLHLNEKFKKISFYNDDYKYTATMMEDVQIKDVVSIKYGNTLIEGGSGIG
                     KTAIMLSRAIKLAKVYPHHKLVIFTHTKQLCNELRERIELLYKDNNNLEVHTFSSFIF
                     KLAKKFNLIVDYNMLKNDYEKTFNNLVKQAQNIIKNKNMFKAIFIDEAESFLEYEIDF
                     IREFLYKTKFIFNVCSCNSLNISNRLNIFKKLYNGIEFDDKIILSKNYRQAKEIVDFT
                     NKFSNNSNSYINELRPNTEFSTFFYTKALRGGNKSVDIIKVSDLDDQISSVIWEIEYL
                     ISKKGLDYSEVAIVYPYNKKKLKSGKTIYFQYMLKKALEEAKIPYICAEDNLTNISKK
                     VGTTIANIYAIKNLEYKAVIVCELEMLYNQTINDIEQDYQVNDFVGDLNKVYLAMSRA
                     TDYLSIVTTFNEEASDIIRLITESKDI"
     gene            complement(16209..17750)
                     /gene="rny"
                     /locus_tag="KR294_001618"
     CDS             complement(16209..17750)
                     /gene="rny"
                     /locus_tag="KR294_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HBH0239700.1"
                     /translation="MDVIDSVVMIVIGAAVGIIAGYFVRKNISEAKIGQAENLAKEII
                     DKAHHDSETVQKEKLLEAKEEIHKWRTEAERENRERRTEVQKYEKRVVQKEEVLDRKL
                     QNLESKEVNLSEKLKVVEKKEEEVEVIKTQQLEKLESISGITSDKAKEIILTNAERDV
                     RREMSIMIKEIESQAKEEADKKSREIIGYAIQKCAADHVAETTVTVVSLPNDEMKGRI
                     IGREGRNIRTLETLTGIDLIIDDTPEAVILSGFDPIRREIARIALEKLIADGRIHPAR
                     IEEMVEKARKEVDNIIKEYGEQAAFETSVHGIHPELIRLLGRLNYRTSYGQNVLKHSI
                     EVAHIAGIMAAEIGADIRLAKRAGLLHDIGKAVDHEMEGTHVEIGMDLLRRYKESKEV
                     IHAMSTHHGDYEPQTVEAVLVTAADAISAARPGARRETLEAYIKRLEKLEEIANSYEG
                     VEKSFAIQAGREIRIMVKPEAINDEEIHLLARDMTKKIEDELEYPGQIKVSIIRETRA
                     IEYAK"
     gene            complement(17926..18972)
                     /gene="recA"
                     /locus_tag="KR294_001619"
     CDS             complement(17926..18972)
                     /gene="recA"
                     /locus_tag="KR294_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HBH0239701.1"
                     /translation="MSVDQEKLKALNEALGKIEKDFGKGSVMKLGEATSMSIDVISTG
                     AIGLDIAIGIGGLPRGRIVEVYGPESSGKTTVALSCVASAQKDGGIAAFIDAEHALDP
                     VYAKALGVDVDNLIISQPDTGEQALEIAEALIRSGAIDIIVIDSVAALVPKAEIDGDM
                     GDSHVGLQARLMSQALRKLTGSIKKSNCVAIFINQLREKVGIMFGNPETTTGGRALKF
                     YSSVRLDVRKIDTIKQGDKVIGSRTRVKVVKNKVAPPFKQAEFDIMYGEGISKIGDLL
                     DIAADVDIVKKSGSWYSYNDTKLGQGRENVKKFLEDNLDLTTEIDEKVRAFYNLNEEH
                     EESGISVSKEIVEE"
     gene            complement(19260..19802)
                     /gene="pgsA"
                     /locus_tag="KR294_001620"
     CDS             complement(19260..19802)
                     /gene="pgsA"
                     /locus_tag="KR294_001620"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HBH0239702.1"
                     /translation="MNLPNKLTLFRIFLIPVFVLIMLLNVPNKFLIACIIFIIASITD
                     ALDGKIARKYNLVTDFGKFMDPLADKLLVISALTCMIEDHLVSSWMVIIIVARELTVS
                     ILRAIAAADGKVIAAGNSGKLKTITQMVSIVFLLLGAQFENVLILNIGEILILIATLL
                     TLYSGWEYLYKNKELFMSSK"
     gene            complement(19789..21123)
                     /gene="rimO"
                     /locus_tag="KR294_001621"
     CDS             complement(19789..21123)
                     /gene="rimO"
                     /locus_tag="KR294_001621"
                     /EC_number="2.8.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12 methylthiotransferase
                     RimO"
                     /protein_id="HBH0239703.1"
                     /translation="MLKIALESLGCSKNLVDAEIMMGILNNKGYKLIGDFEEADVIIV
                     NTCGFIESAKQESIDTIINFAELKKTGNLKLLIVTGCLAQRYSEELKTEIPEIDAIVG
                     TGSYQNIDKILKELSEMHQIVSLNDIEFVFNEDLPRYISTPSYMAYLKIGEGCSNNCT
                     YCIIPKLRGKYRSRKFEDIIKEAKKLAESGVKELVVIAQDTTKYGFDLYGKERLSELL
                     EELAKIDGFKWIRVMYSYPESITEELIQVIKKYDNICSYFDMPIQHASNNILKLMNRK
                     TTKEDILNKINLIRSNIPDAILRTTIIVGFPGETEDDFKQLVDFVEEVKFDRLGAFAY
                     SREEDTPADRLPNHIDEEVKIQRRDTLMMIQQKISEELNDKKIGKTYEVLIEEQIEDN
                     VYTGRTQGDAEEIDSIVYVKSVDNLEVGEFVSVQINDAMEYDLMGDVLYELA"
     gene            complement(21117..22175)
                     /gene="mnmH"
                     /locus_tag="KR294_001622"
     CDS             complement(21117..22175)
                     /gene="mnmH"
                     /locus_tag="KR294_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-selenouridine(34) synthase MnmH"
                     /protein_id="HBH0239704.1"
                     /translation="MSVIKIEKALKLDKVIFVDVRTEGEYEEDHILNAINMPLFKNNE
                     HNEVGTIYKMQGKHEAIQKGFDYVSYKLKDIYLQAAELALNYDNIVIYCARGGMRSGS
                     IVNLLSSLGVNVYQLEGGYKAYRNFVLEYLRHVMDTKNFVSVHGLTGTGKTDLLHLLD
                     EKGIDVLDLEGIAKNSGSTFGFITFDKKPPSQKNFETKLFESIFFSKENYIFVESESK
                     RVGSVTVPNEIFEAMTREGHHILLECDIENRVDRLCRDYIYDKDEGNILILKECINKF
                     RKRLGNKVVDDYIDLLESGEYKELVKRYLLEYYDPLYMHSVEKYKYSKIINFNDTQKA
                     LEDVIDLYESILEGESEC"
     gene            complement(22178..24589)
                     /locus_tag="KR294_001623"
     CDS             complement(22178..24589)
                     /locus_tag="KR294_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HBH0239705.1"
                     /translation="MATKKKKKKKVNTLSFNAEYHNLITIFIGVFLLYSLNSNSMGWI
                     PVLMQNLFKGLFGGLSIAIPFIVIITGLLGFFDGNEYIYRLRKTKLYYIIILFIFVFY
                     GLLNAGTLPVDSPLKGNMFDDVMKLGVSGQGSGLIATTIAYYMSKIFGIAGGWLISIF
                     ALILSVMFIFNISIKDLVSNAKSKSKASKDSNLTFKDKIANMKKSAIDMMTDEVDDTT
                     INKKPGFFKGLMSKGLNNDDEEDEYFEEENSDGVDDKTIKIVGFNKAEDEYLEILEGT
                     QSMPELDVLKELQKATNENPVVDTKPEKKVDIAKPNLNIEKTQPMSIVAEPVNEDYSN
                     YKKPSIELLNKVNKKSDENGKKKVLKNASLLEKTLSDFGVEAKINQVTVGPTITRYEI
                     QPSPGVKVSKIVNLTDDIALSLAAKSIRIEAPIPGKSAIGIEVPNEEAQMVGVREVLE
                     SEEFNNFNSPLAMGLGKDVAGKIIIGDIGKMPHLLIAGSTGSGKSVCVNTLISSILYK
                     ANPDEVKLLLIDPKVVELANYNGIPHLLIPVVTDPKKAANALNWAVTEMNRRYKLFAD
                     AQVKDVTSYNEKAEEKLPKIVIIIDELADLMMASANDVEDYICRLAQMARAAGMHLIV
                     ATQRPSVDVITGVIKANIPSRIAFAVSSQTDSRTILDMGGAEKLLGKGDMLFYPLGAA
                     KPVRLQGAFISESESEKVIDFVKSQVKDGIKYEEDIIETISKVNTSKGSDEDEFLSEA
                     IEFVVESGQASASMLQRRFKIGFNRAARLIDSMEERGIIGASEGSKPRKVLISKQDLQ
                     NLEGE"
     gene            complement(24712..25446)
                     /locus_tag="KR294_001624"
     CDS             complement(24712..25446)
                     /locus_tag="KR294_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit"
                     /protein_id="HBH0239706.1"
                     /translation="MKDYREDNEKFDKDNCSEESSCEERECIKQFGTNEMPPQPPKDI
                     QCITIIGEIEGHFIGNPQKKATKYEHIIPMLYSIEESNDVKGVLVVLNTVGGDIEAGL
                     AIAELLNSTSKKVVTLVLGGSHSIGVPLATAGDYSFIAPTATMIIHPVRTTGLVIGIN
                     ETFEYFKKMQDRIIQFIIRTSNIKKDVLEKLMHEKDELVSDVGSVLIGKEAVDYGLID
                     EVGGLKEALKKLRELIKESEEEKNND"
     gene            complement(25559..26782)
                     /gene="dapG"
                     /locus_tag="KR294_001625"
     CDS             complement(25559..26782)
                     /gene="dapG"
                     /locus_tag="KR294_001625"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HBH0239707.1"
                     /translation="MSILVQKFGGTSVESYEKMNEVCKIVKAYKKNDEELQLVLVVSA
                     MGRKGAPYATDTLINLCSAVNDEPSKRELDLIMSCGEIISGTILANLLNAQGIDSVFF
                     TGQQAGIITSDEYSNAKIKYINPKKVKRALDDGKVVVIAGFQGVTDDGEITTLGRGGS
                     DTSAVAIGKALECETVEIYTDVDGIMTADPRVEPNAKVLSFIDYEEVFQMADKGAKVI
                     HPRAVQLAKSGNITLAIKNTMNPTFEGTKIGSLCRHLEDNIEYEQERDFKVAVANKDS
                     VAQVKIKSAEEVFTEVLNEIEKKLITIDMINFFISEKAFVVEDADIKSLKEILDKFEL
                     DYEVNRDCAKVTLICSRIADEMSGIMSKVVRGLSKAGVSLLQTSDSNMTISCLVSEED
                     MHTAVHAIHQQFYLK"
     gene            complement(26792..27037)
                     /locus_tag="KR294_001626"
     CDS             complement(26792..27037)
                     /locus_tag="KR294_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlmC/YmxH family sporulation protein"
                     /protein_id="HBH0239708.1"
                     /translation="MNLSEIAGKEIVNLVTGERLGVIGECDLILDETTGDILALLIPK
                     EKGFFARRKDKSFLEVPWRNVKKIGNDMIIIEYEGYI"
     gene            complement(27072..28319)
                     /locus_tag="KR294_001627"
     CDS             complement(27072..28319)
                     /locus_tag="KR294_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HBH0239709.1"
                     /translation="MYKTKILENGLTIIGEEIPYLKSITLGIWINAGSRIEEAQVSGI
                     SHFIEHMMFKGTKNRTSKEIASSIDNLGGQINAFTSKECTCYYVKLIDEHIDTGIDVL
                     SDMILNSKFDKNDIDKERLIILEELKMYEDSPDDLSYDLLVENIYANDGLGMNIIGTK
                     ESLYNITRESMLEYLNKYYIPNNAVISIAGNFNFDDMVEKIKSKFGHWEKKNLSIDIS
                     EAKFNPCFISKNKDTEQVNLAMCLKGIPFENDEEVYSMAVVNNIFGGSISSRLFQKIR
                     EEKGLVYSIYSSQTLYRKCGELGIFASMSTENLQDVYNLIKKEIENIRENYLTEKEIS
                     ESKEQLKGNYILDLESTSSRMMSTGKSMLLSKKVKTTDEILECINNVNINSIKKVVDK
                     VFNIENIGTCIVGRDVEKILHLD"
     gene            complement(28477..29220)
                     /locus_tag="KR294_001628"
     CDS             complement(28477..29220)
                     /locus_tag="KR294_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBH0239710.1"
                     /translation="MIMMVLNKSKLKKIIILILVVLLVLSGGVMVLKLFNNKPVFNLF
                     NGVDLPYERGTKDKSGYVALTCNIDLGWETEYVESILETLKKENVKITFNVTGKWAEK
                     NKDELLKIKKQGHEIGNHGYKHLDYSTLSYEDNYEQIETSKKIIEEIIGEKTKFFQAP
                     AGSFGPETVKAAKALGYTSIKWDADTIDWKYKDQPEVIIDRMKKKDIKDSSIILMHPT
                     NATTKCIDDIIAIVREKGLKPGKLSDVFK"
     gene            complement(29486..31597)
                     /gene="pnp"
                     /locus_tag="KR294_001629"
     CDS             complement(29486..31597)
                     /gene="pnp"
                     /locus_tag="KR294_001629"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HBH0239711.1"
                     /translation="MFEHKIFKMDFAGRELSVEIGKICEMASGSCIVRYSDSMVMVNT
                     TKSAKPRDGIDFFPLSVDYEEKLYSVGKIPGGFLKREGKPSEKAILTSRLIDRPIRPL
                     FPKGFRNDVQVVATVLSVDQDCTPDIVAMIGSSIALSISDIPFNGPTGSVCVGLVDGA
                     FVVNPNAEQREKSSMHLVVSGTKEAIMMVEAGADEVPDEVMLDAILFAHQEIKKIVEF
                     IEGIVAEVGKEKMPVELYHAGEEITQLVREFATDKMKKAVQTFEKLERMENMDRVKEE
                     TLAHFEETLEDFEDFVGDIEEVLQDIIKEEVRKLIVHENVRPDNRKLEEIRPIWCETG
                     MIPRAHGSAIFTRGQTQVLNVATLGALGDVQKLDGLDEEENKRYMHHYNFPAYSVGEA
                     RPSRGPGRREIGHGALAERALLPVIPSQEEFPYAIRLVSEVLSSNGSTSQASVCGSTL
                     SLLDAGVPIKDMVAGIAMGLIKHDGKVAVLSDIQGMEDHLGDMDFKVAGTEYGITAIQ
                     MDIKIDGIDKEILQRALKQAKEGRIHILGEMRKTISQPKPELSPYAPKIVKMQINPDK
                     IKDVIGPGGKIITKIIDETGVKIDIEQTGEVFISGIEIDMIKKAQELINNIVVEPEVG
                     KTYKGKVSRIMNFGAFVEILPGKEGLLHISHIAHERVAKVEDVLNIGDEVEVKVTEID
                     EKGRVNLSRKVLLPKPEHKNK"
     gene            complement(31722..32567)
                     /locus_tag="KR294_001630"
     CDS             complement(31722..32567)
                     /locus_tag="KR294_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBH0239712.1"
                     /translation="MKIKLVCDSLCDIPDEISEKDYIEIVPLTVIFNDREYIEGVDIK
                     KEEFYKKVKEIKQIPKTSQATYMEFKEVFDKFITEGYHIICMTGAANASGTFQSAMIA
                     KNDVNENEKIHIFDTRNLSLGSGQYVIKACELLEEGLGFEEIIDELENTRSSVRLLFA
                     PYTLDFLKQSGRVPVATALIGNMLNIKPIFFFDNGEAKLVNKVRGIKNIASKLVDIIL
                     EMNEGSLEGKIVTIGCGDNLHDCEILKDEVNKRIKARRVLFTRGGVSICSHTGPDILA
                     ISCSN"
     gene            complement(32807..33064)
                     /gene="rpsO"
                     /locus_tag="KR294_001631"
     CDS             complement(32807..33064)
                     /gene="rpsO"
                     /locus_tag="KR294_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002843739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HBH0239713.1"
                     /translation="MINKSEIIKEYGRAEGDTGSPEVQIALLTARINELNGHLKTHKK
                     DHHSRRGLLKMVGRRRNLLAYLKEKDLEGYRALIAKLGLRK"
     gene            complement(33168..34097)
                     /locus_tag="KR294_001632"
     CDS             complement(33168..34097)
                     /locus_tag="KR294_001632"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HBH0239714.1"
                     /translation="MVIIKSIKEIANIKESVITIGNFDGVHKGHQVLIGKTVEHAKKE
                     NIQSIVFTFANHPVNYFRPNSTKNIISNDDKIKLLEDLGIDIVVIIPFDEYMTKIPAK
                     DFVDEILVKKLKAKKIVIGHDFTFARAKEGNVNLLKSLEHEFGFEVEVIKPIKINDVR
                     VSSTYIRSLVSQGDMANVKEYLGRNYKLEGCVIHSKHLGRTIGFPTANIDLKNNMLVP
                     KRGIYASIVHIGDETYFGATNVGYNPTVNGKTLSIETNILEFDRDIYGENIIVEFLER
                     IRDERKFNSIDDLKNQLYNDTNYVYENYVCKNK"
     gene            complement(34228..35133)
                     /gene="truB"
                     /locus_tag="KR294_001633"
     CDS             complement(34228..35133)
                     /gene="truB"
                     /locus_tag="KR294_001633"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HBH0239715.1"
                     /translation="MNKIISILKPTGMTSHDVVSRVRKILNIKKVGHTGTLDPDASGV
                     LPICIGKATKVCEVILNKDKSYICELTLGISTDTYDASGEILKKVDDFKFSNEDIERA
                     FDTQRGEINQLPPIYSALKVNGKRMCDLVRSGRQSEITLKTRRVNIKDIKILSIKGNK
                     VMFYVECSKGTYVRSICHDIGEYLGCGAHMSFLNRTSSGKFDLDNSITLEELELFYEN
                     KTLDKYLYDIDYVLDSFNYVVLNPNAIKYYSNGGSIDDKRFLKNNFDKDDEFVRVYST
                     DNFLGLGKLSKHNNTISVKSDKMFI"
     gene            complement(35146..35451)
                     /locus_tag="KR294_001634"
                     /pseudo
     CDS             complement(35146..35451)
                     /locus_tag="KR294_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438308.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
     gene            complement(35569..>36666)
                     /locus_tag="KR294_001635"
     CDS             complement(35569..>36666)
                     /locus_tag="KR294_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBH0239716.1"
                     /translation="YKFRMYPNKKQQELINKTFGCCRFVYNKYLAKRIDVYKSDKETF
                     TYKQCSSDLTNLKKELKWLKEPDKFSLQNALKDLDNAYKKFFKEKAGFPKFKSKKINR
                     FSYKTNFTNGNIMYCGQYIKLPKLGMVKIRDKQVPQGRILNATISKEPSGRYYVSLCC
                     TDVDIEVFENTNNHIGLDLGIKEFCISSCGDFIENPKYLKKSLNKLAKLQRELSRKTI
                     GSLNRNKARLKVAGLQEHIANQRNDFLQKLSTKLIKENDIICIEDLQVKNMIRNRKLS
                     RLISDVSWSEFIRQLEYKANWYGRKIVKVGKFFASSQICNKCGYKNEEVKDLNIREWI
                     CPSCNETHDRDINASINILKEGLRLITIQNK"
BASE COUNT        11557 a         6445 c         3984 g        14680 t
ORIGIN      
        1 aaactttatg gaatacataa ttttcgattt ggaatttaac caaggatttg ataaaaaact
       61 caataaaact gtatccaatg aaaagtgtcc ttttgaaatt atacaaatag gagcaattaa
      121 attggattct aaattcaata taatagatac gtttaatagt tatgtaaaac ctacaattta
      181 taaagacata catcccttta ttagtcgtat gactaatatt aaaaattctg attttaatga
      241 ttcgcctact ttccctgagg tctacaacaa ttttataaaa tttatatcat cacaagaccc
      301 tatattatgt gtttggggag ctggagattt aaaggaatta tacaggaata tcaactatca
      361 caagctacca tcaaattcct tacctaaatc ttatattaat atacaacaac atgcatctaa
      421 atatttcaat aatccagcag gaaaaagcat tggcctacaa aatgctattt ctatattaga
      481 acttgatgaa aaaatgtctt atcacaatgc tttaaatgat gcatattata ctgctaaagt
      541 ttttattaag atatacaatc caagtatagt cccagatata tatctttata caagtataaa
      601 acctaaaact ataagatatt ctaacaaaaa aagagttgat tatgataagt tatttgatga
      661 atttaggaaa attttaaatc gtgaattaac taaagacgag aaaaaaatca ttaacttagc
      721 ttataatatg gggaaaacaa atcaatttac attagaaaat gttaagcaaa gaaaaaacaa
      781 atagagttta tttagataaa aaataggcat gtagattaaa aaactagtta actttaaatt
      841 tatatctaca gcccaatttt tatcataatt aatttttatt ttatctctaa ttcaactgga
      901 caatggtctg aacctaatat ttcagtgtgt atatccgcac ttactaatct atcttctaat
      961 tttttggatg cacaaaaata atctattctc caccctgcat tattttttct tgcattaaat
     1021 ctatatgacc accaactata aacaccttct ttatcaggat taaaatatct atatgtgtct
     1081 ataaacccac tgtctaataa tttagaaaac ttctctcttt cttctttagt aaaacctgca
     1141 tttttcatat tatttttagg attttttaaa tctatttctt tatgtgcaac gttcatatct
     1201 ccacacacaa ttacaggctt atgattatct agtttggtta aataatctat aaagtcgtct
     1261 tcccatctag ttctatattc tagtctcttt aattcagatt gagaatttgg cgtatatact
     1321 gtaacaaagt aaaaatcttc aaactctaga gttatcactc taccctcttt gtcatgttct
     1381 tctatattta ttccatacat tacttttaaa ggctcttttt ttgtaaatat agcagtacct
     1441 gaataaccct ttctctcagc ataattccaa tattgaaaat atcctggtaa atctaactct
     1501 atttgccctt cttgcaattt agtttcttgt aaacaaaata tatctgcatc tacttctttg
     1561 aaaaagtcta aaaatccttt cccaacacaa gctcttattc cattaacatt ccatgatata
     1621 aatttcatac ttatactcct catctaaaca ttgacacact ccccatagct aaagatgggg
     1681 gcttttcaac aattttattg taaattctta attcactttt attttaacaa tgctatacta
     1741 taatttcatc taaaattact atttacttaa tacctaaaaa tatatgtttt aatcaatttt
     1801 taactttttt gttaaatctt cagggctcat tgaagaaaca tacatatttg ttccaagttc
     1861 aaatcctcca aaattatatt ttcttgggat tatgtgcata tgaacattaa aatacgattt
     1921 tgtttcaatc tttgttggat gagtgtgaat acataaatta aatggcatat atccattgat
     1981 attatataac ttcttaaaca acttttcaaa tattgtagaa agctcctgta tattattatc
     2041 atttaactca ccaaactcta ttttatcttt aaatattatt cttacttctc cactatactt
     2101 ggttgcatat ggtataagta ccaaaaaagc ttctccatta taaacaactc ttctatctaa
     2161 acttatttca ttttctatta aatcatcata caaagagctt ttattgctgt cataatactc
     2221 ctttgaaacc aacagttcat tcgtaatttc aggtggaata aaagacatag acaatatttg
     2281 agcatgtgga tgcatcaaag atgctcctgc ctttctcaag aagtttttga agatactaac
     2341 atactctact ttatcatctt tcgacaaatc tctaaatcta tttctataca taaaaaaaac
     2401 atcttcaaat tctttttgac tcatgttata aaaactacga ttatgtttat cgctctctat
     2461 cattacttca tgaacaccat atacatctct tgccatatca tcaattatag gaaatttatt
     2521 gtagacagat tttacaagcc atccttcttc actttctatt tcaaataatg catcagttgc
     2581 atgagcttca tttcctttgc aaaatgggca ttcttcatca tattcattag tttcttcatc
     2641 ttcatttggg atatctgctg tatctaaagg tctttttaac ctatctgtag caaatataac
     2701 aacatcattg gtaattggat ctattcttaa ttctttcata attaacacct cttagttaat
     2761 agcctttaat ataattatat gatatttatc gtatctgtta aataaattta taatattttt
     2821 tataattttg catatttatt attatatatt ttgtctatag ctgaaagatt ataactaaaa
     2881 aatcactatc agtatatcag aatattatct tactataaat taatttatga atacataatt
     2941 tagtggcata aacatgggta ttttactata atttgttaaa agtttatttt aaagctatat
     3001 taattttttt tgatgatttt tacccataag tatgttatta ttatcttgta aagatgtctt
     3061 gtattcaaac atacaattta cataatacaa tatacgtatt taaattaaat agggggtatt
     3121 aaaatgaatt attcaaacag agttagtgca atgcaagcct ctccaatcag aaaacttgtt
     3181 ccatttgcac aagcagcaaa agataaagga atcaaagtat atcacttaaa cataggacaa
     3241 ccagacataa aaactcctaa aggatttttt gatgctgtta aaaactttga tagcgaagtc
     3301 ttagaatatg ctacatcaga aggtattcca gaattattag aagcacttca aaattactat
     3361 aaaacttacg atatgaattt tgaaaaagat gaattattag taactaatgg tggtagtgaa
     3421 gctttacttt tcactatgat ggcagtttgt gacccaggag ataatctatt agttccagaa
     3481 ccattctata caaactacaa tggatttggt caatctgtaa acgtagaagt taatgctgtt
     3541 acaacaaagg cagaaaacgg tttccacctt ccatctaaag aagaaatatt gtctaaagta
     3601 gatgataaaa ctaaggctat aattctttct aacccaggaa atccaactgg tgcaatttat
     3661 acaaaagaag aacttaatat cctagctgaa atagctaaag aaaaagattt atggataata
     3721 gcagatgaag tttatagaga atttgtttat gatgggcttg agtatacaag ctgtggtaac
     3781 ttagagggtg tacaggatag agttataata atagacagtg tttctaagag atacagtgct
     3841 tgtggtgcta gaattggttc tatcgcttgc aaaaataaag gtcttatcgc tcaaatcctt
     3901 aaattatgtc aaggaagact ttgtgttcct acattagagc aaataggagc tgttgagtta
     3961 tacaaaactc ctgtttctta cttcaaagaa gttaatgaag agtacaaaaa aagaagagat
     4021 gtattataca atgaattaat gaaggttgaa ggtgttatat gtaaaaaacc aactggtgct
     4081 ttctatatag ttgctaaatt accagttgaa aatgcagaag atttcacaat ttggatgtta
     4141 aaagaattta acaaagataa tgaaacagtt atggtttgcc ctgctgaagg attctatgct
     4201 actccaggtt taggacgtga tgaaataaga ttagcttaca tcttaaatga aaaagacctt
     4261 catagagctg ctacattatt aaaagaaggt ttagagcaat atgtagcttt acaaaaataa
     4321 ttttttaaac ttaatttata taaatttaat gatataaaat gtcccctttt cagatattat
     4381 ttgaaaaggg gacatttctt aattaatata ttaattaaga cttagacctg actatttttc
     4441 attttcttta tatagtgttg gccagtaatc tttattcact ttaattaaag catctaaaac
     4501 ttgtcttgcc ttagttggag agattatagt tctatttaat gttaaagata aaatagcttt
     4561 ttcataagat tgttcaaagt atgcatcaac tgctaacttt tcataagcta gttgaccttc
     4621 taacagtccc ttataaaatg ttggtatatt acctacatgt aaaggtctcg gtccattctt
     4681 tgtaagaatc gcagctactt ctaccattgc atcatcaggt aagttgctaa tagccccatt
     4741 attttctgtt ataactatgg ctatttggtg tttgttatga gctattgctt ctgcaacttc
     4801 aactataaat tccccatgag catcattatg cactaaatta gaacctatag atgttccttt
     4861 ttctataaca gatttacatt cttcaaatac acgcttttct cttccattca taacttctct
     4921 tgctctagta caatttatat ttgatttagc tactttttta tcaggatata gataatactg
     4981 tacatatgta ttaggtaagt aatctggtac atcttccaac atatctttaa ccattccata
     5041 agtgtctaac caagatttat ctctttgttc tgcatcaaca ggttggaatc cagagtttgc
     5101 tactaaatct tttatcttag gtaccaaatc ttcaccattt ttatcataca aatgtgtaaa
     5161 ccatccaaag tgatttaatc caaagtatac aggctcaaat gttcttgaat ccatgtctaa
     5221 caatcttcca taagacctta acaagttaac tggttggtca cacatattaa gtaatctttt
     5281 atcatctgga aatactcttt ttaatgcttc tgcaacaata gcagcaggat ttgtataatt
     5341 taatatccat gctttaggag agtattttct tacagtctta accatttcta tcatatcacc
     5401 tatagacctt aacccataag caaatccacc agctccacaa gtttcttgac caaccagtcc
     5461 aaattgtaga ggaatctttt catctaattc tcgcatctta agaccaccag ttctcatttg
     5521 aacaaataca aaatctacat ctataaatgc ttcatctggg tttgtagtat attcaagtgt
     5581 tgctttagga tattcttctt taaataatat ttttccaaat tcccctatta atctttgacg
     5641 ttcttctact acatctaaca tagttacttt atttagagga aatctatcac tcattttaca
     5701 taaagacttt aaaagtcctg gagtccaagt actgcctcct ccaactatag ctatattgta
     5761 tctttttttc attgtcatat taatcacccc tgttttttat taactaactt gtaagatgat
     5821 tataatatat aaagttttct acatgaatac ttttaggtaa tcattaaaaa tagttcaatt
     5881 ttagtatttt tttcaaaatt gtaatttttt tcatctattg tatttttcaa tgtatttatg
     5941 aaacatatat tccataagag aaagtgctgg cactctagat gtatagttaa cactattaaa
     6001 attatattgt ggagaagata caaataattt tatatcagct atatttgata atgaattgac
     6061 acttatattt gtcagagaaa ttactttaac ttgatttgtt tttgctatat tacatgcctt
     6121 aataacttga gcagtctctc cagacataga tacagcaatt acaaggtcat ctttagtaat
     6181 atttgatgca gccaaataca tgagagttga atcatcatag tattttacat ttacacctat
     6241 agctgaaaaa cgttgagaca tttcagtaca tactaatcta gaagacccaa caccaaaaaa
     6301 atatatatgc ttagaattat gtatttcatt taaacacata tctatattct ctacatttat
     6361 taaattttgt gtatccataa catcagtaaa aatatcactt tgacttttag taaactcctt
     6421 atttctttca tttctatttg aatatgaaaa aactaaaaag tttttaaatt cactatatcc
     6481 agaaaagccg agcttctgac aaaaccttac tatgtatgca gtcgaattaa aagtttcatt
     6541 tgctatatct ttaatctttt tttgatttat tttttcagaa ttttttagaa aatagtttaa
     6601 aagagatatt tcatttgtag ataatttttt ttgatttata tctaatttgt ctattaggtt
     6661 catttatacc tccataataa tgatttgtag ttaaacaact ttctcatatt tattatataa
     6721 atatacacta tacagcattt atcttatgtt tattatacta taaaaaagac aatacaaatt
     6781 ataaattagt attgcctttt aatatttact ttaaatagac attgcaaaag aaacttcgtc
     6841 tcttacttga gatacagatg gcccataaat tatttggata tctttatcag atacttttat
     6901 aactcccatt gcacctgtat attttttaaa agcattttca tctactttac tcatatcttt
     6961 aactactact cttaagcgag ttatacagtt tgttatatct tctatattgt ccttaccacc
     7021 taaatattta attatagata atgctctctt agtagtttct ccactttgag ctatttctac
     7081 tttatttgat aaaggtttta aatcaaaatt tatatctgtt atttcttctc gtcctggagt
     7141 ttgtaagtta aatctaagta tcaaaatctt aaatacatta taataaacta ttgcatacac
     7201 taaaccaagt attatagaat aaatccactt tgtatttggt tgcataactc caaatactac
     7261 taaatctatt atgccacctt gagtatttcc tattgctact ccaaatatat gcatcatcat
     7321 aaatgatata cctgataaaa atgcatgtat aacaaataat attggtgata caaataagaa
     7381 tgaaaattcc aatggttccg taattcctgt tacaaatgtt gctaaagcac cagctagtaa
     7441 tataccttta accttcgacc tattttcagg ctttgcagtt ttatacatgg catatgcagc
     7501 agcaggaaga ccaaatacca ttataggtat tttcccttga gctaaaaatc tagttgcttc
     7561 tgttgaaaaa ctgattgttt cagggtcact tagttgagct aagaatatgt tcaatgctcc
     7621 aaatacttct tgccctccca caactaaaga acctcctact tcagtaaatc taaacatagc
     7681 atttaatata tgatgtaatc caaatggtat taaaagtctt tcaagaaatc caaatacaaa
     7741 tgttcctaaa tatcctaaac tagctatacc aatacctaca ctctgaataa ttgtatttac
     7801 atatggccat atatatggta ttattatccc caaaatagag aatactactg ttgttattat
     7861 tggaacaaac ctagttccac caaagaatcc taaataatct ggcagtttta tattatagta
     7921 tttattatgt aatgatgctg ttattatacc aactacaatt ccaccaaata ctcctaattc
     7981 taatgtttgt atgcctaaag ttacagcttg acccatttct ctcatcatgt caggttcagc
     8041 aataatcccc ctacacccta acatataatt tacactagtg tgtaatacta aataaccaac
     8101 aaaaccagaa aatgcagaaa ctgctttttc ttctttagca agaccaacag atattgatat
     8161 agcaaagaat attgctaagt ttccaaaaag tactcctgtt atagcttttg taaaacccaa
     8221 tattccttga ataaaattat ttgctaaaaa aggcatatca ctaactatat taggatttga
     8281 aaatgctgaa cttattccta aaaatatacc tgctgcagat attaatgcta ttggcaataa
     8341 aaatgatttt cctaactgta aaaagaaccc tttcattttt tgtttcattt ctatccctcc
     8401 atttttaaat ttttaaaacg ttttctatgt cataattata tatttttatt ttgtttttga
     8461 aactttataa tttgttttaa aatattttta cataaatagt aattttttca aaactgtaaa
     8521 ttttttcaaa caaagacata gtaacgttgt aacatatata aatttaaaaa gagcttagaa
     8581 aataaaatta ttgaatataa aatggaaaaa tataaattac acaaagagat atgagtacgt
     8641 actaacaaat acgaaaatgt ataagaaatt ataaaaaagt acatcaagaa aatttaagat
     8701 gtacttttta gattgtattt agacttataa ttatatagtt aaatgaataa caaagaatta
     8761 atcttagtac tattaaatac aaaaattttt atattttttc tatctaaatt cttctttgtt
     8821 taatatatat tgaagagtat ttattgcttc taaatatttt tttctgtctt cttcagttaa
     8881 tttagaaagt ttttctccta aaccatcact taatttatcc ataaaatcag ttgctatctt
     8941 atctccctct tcagtaatgt caattagata ttttcttcta tcaactaaat ctcttttcct
     9001 tgttacatac ttcttatcag ttaaatcatc aaccatacta gttaaactgc ctttttctat
     9061 atttaactta gagcataaat cagtcatact tattactcca taatttttta tgaaaactaa
     9121 tgctcttaat tgtgttttat ttacattata atctggtgca aattttttta ggtcttctaa
     9181 gtacaggcta gaataaatct taggaaatgt ttttactaaa aaacttatgg tatcttttac
     9241 tatatagttc atataatcac ctcggttgtt ttaaaattta ttaaattatc taaataactt
     9301 tatttcagtt tacattaaaa atattgcaag tacaatagtt tttgctgaat gtttaaattt
     9361 aattagtaat cttatcattt ttttattttt atttatatta ttcctattaa atattattta
     9421 tatagctatt ttattaaatt catggtatag taagtaaaga agaactcttc acagcggtgg
     9481 agagaagacg ctagcccatt aaaatggcta tcttatttat aaataagata gccgttttta
     9541 attatatttt atctgtacaa ttctatactc ttaagtctac atctactttt cctaagtctt
     9601 ccttataatc ttttatagca ggttctacaa cttcatttac aaattctaca acttgttctg
     9661 gagctctacc tataaagttt tttgggtcca ttatagatag tatttcttcc ttgctcattt
     9721 taaatgaatc atcattcatt ataagttcaa ttaagttatt atccttgcct tcatgcttta
     9781 ctctataggc agctttcata gaatattctc ttattatttc atgtaattcc tgtctatctc
     9841 cacctctttt tacagcttcc ataagtattg tttctgtagc cataaaagga agttcttcat
     9901 ttacacgtct atttatcata ttttcatata ctactaaacc atcagttaca tttatcccta
     9961 tttcaagtat agcatctgct gccataaatg cttgaggtat tgccaatctc ttattggctg
    10021 agtcatctaa tgttctctct aaccattgag tggcttgtac cattgcaggg cttatagatt
    10081 cagagattat atacttagat aaagatgcta ttctctcact tctcattgga ttcctcttat
    10141 aagccattgc tgatgaacct atttgatttt tttcaaatgg ctcttctaat tcttttaaac
    10201 tttgtaaaag tcttatatca ttagtcatct tatgcatact ttgagctatc cctgatagta
    10261 tgcttattac ttgataatct aactttctag tatatgtctg tccacttact gcataggaag
    10321 aatggtatcc catcttttta caaattttct tatctaactc ttttactttt tcgtggtctc
    10381 cttcaaataa gcttaaaaaa cttgcttgag taccagtagt acctttaact cctcttaact
    10441 tcatgttgtc tattctatag tttaaatctt ccaaatcaag aattaaatct tgagcccata
    10501 aacaagctct ttttcctact gttgtaagtt gagcagcttg gaagtgtgta aatccaagag
    10561 ctggcatatc tttgtactta agtgcaaatt cttttaaatt gtttattaaa tttacaagct
    10621 ttactcttag aagttttaaa gcttcattca tttgtataac atctgtatta tctccaacat
    10681 atgcagatgt tgctcctaaa tgtattattc ctttggcttt ttcacattgt aaaccataag
    10741 cttttacgtg agacattaca tcatgtctta cttctttttc tatttttcta gcttcatcaa
    10801 aatttatatt atctatatta gctcttagct catctaattg ttcttcagtt atattgattc
    10861 ctaactcatg ttcaccttct gcaagtgcaa cccataacct tctccatgta gagaatttaa
    10921 attgtggaga aaatatataa ctcatgtcct tgctacaata tctgtctgta agtgggtttg
    10981 agtaagtagt atatttatta tctatcatta tattagcacc ttccttaaat cttttgtcgt
    11041 gtgattactg tgtacacatt agtacataaa taattatata taattttacg aactataaca
    11101 agactttttt attttttgtt cacatttata tatagtattt tttatttatt actatttttt
    11161 atttatatcc aaattatctt tttcaattaa gtaatccact atttcactat caacaaaatt
    11221 taatacatac ttatatctaa ttgcatagta tttatcactc catccaagct gattttttac
    11281 atcactttca tctgccccaa gccttaaact tattgctgca aatgaatgtc taaaatctct
    11341 tgctgaatat tgagaaagtc cagctaaatc taatgctttt ttgactataa gtctgacatt
    11401 tctatctgtt atagaattac tcttttgagt tgtaaaaata aaatcatcac taggtattat
    11461 tacctctgga agcccagaat aattcctgta atcttctaaa agtttaaaaa agtatggatg
    11521 taatttaact actctttctt ttcttccctt acctaacctt acatatgagt tatcgttttc
    11581 atctaccata aggtctttcc actttaagct aactaattca tttaataaac acccagtagt
    11641 aactagacag actattatta ctctatctct tatatttaat tttggtagga tacctataag
    11701 tttatttatt tcttgtatac ttagaacatc atcttttgtt tttattcttg ttactgtggg
    11761 tttttctaca tatctaaatg gatttatatc tatgtatcct tcttttttta agaagttata
    11821 aaaactatgt aaataactat atatcttttc acaagttgat ttcgcatatt tagtctgtat
    11881 atagtctaca aaatttttac aatcttcttt cgtagcataa atcaattctt tcccttttaa
    11941 aaattcttta aacagtataa cctttgataa ataatcgtgt ttcgtgtttg gatttaattt
    12001 tgtagaaaaa acattaaaag tttcatactc ataatcatct agtatttttg tactatacat
    12061 aataactcct ttccttttca taaaataaaa tagctatact tttactatac catatatttc
    12121 cccctcaaat atacccctta ttcaatagat aacttttaag tttattttgt tatattgtga
    12181 aggttttatg aaaatatcaa tcttccattg tgcactacac agtactatgg tattataagt
    12241 tagtaaaagg tggcattttt ttattaatct atgaataaaa tatgctacta taaatttgta
    12301 ttggaggtat tttgatttgg aaacatttag tttgcttgaa atttttaagg cagtcatttt
    12361 gggcatagtt cagggaataa cagaatggct accagtaagt agtacagggc atatgatatt
    12421 agttgatgag tttataaaat tgaatttttc aaatacattt ataagtacat ttttagttgt
    12481 aattcaattt ggttcaatat tagctgtact tgttatattt tttagaaaat taaatccttt
    12541 tgatagcgca aagaatatta agcagaaaaa agaaacagtc cgtttatggc ttaaggttat
    12601 aattgcagtt ataccatctg gagttattgg aatactgttt gaagatgata tagatagatt
    12661 attctttaat tcaacagtag ttgctattgc tcttattgta tatggtataa taatgatagg
    12721 gcttgaaaag agaaataaaa aacctaagta taaagatttt tctcaagtta catataaatt
    12781 agctctttgt ataggattat tccagtgtct agctcttata ccaggtacat ctaggtctgg
    12841 ttctactata ataggtgcag tattacttgg tacttctaga tatgtagcag cagagttttc
    12901 attcttctta gccatcccta caatgcttgg agctagtgca ttaaaacttc taaaagctgg
    12961 atttggattt actggatttg aatggcttat tttaggtgtt ggttctgtag tagcatttgt
    13021 tgtttcaatt gtagttatta aattttttat ggactatatc aaaaaacatg acttcaaagt
    13081 atttggttat tatagaatag tcttgggtat agtggttctt gcttatttct ttctattata
    13141 atgtattcta atttaataac aaatgataag gagaaaagtt atgagtgtta aaaaagaaat
    13201 atttgattgg attaagtcaa tagctatggc tattgtactt gcatttgtaa ttctacaatt
    13261 tataagacct tctattgtaa gtggagaatc aatgtatcct actttagatg ataaagatta
    13321 tctgatttta aataggatat catacaaggt tggtaaacct gaaaaaggcg atattgtagt
    13381 ttttaaaacc aatttagttg atggagaaac aggaaagaaa aaagacttaa taaaaagagt
    13441 tatagctact gaaggtgaca gaataaaaat atcaaattct aaagtgtatg taaatggaaa
    13501 attattaaat gaaccatata tacacaataa ctatacttct ggagatatag atactgttgt
    13561 tccaaaaggt aaactatttg caatgggaga taatagagaa aatagtaatg atagtagatt
    13621 ccctgatgta ggtatggttg atgaagatga agttcttggt aaggttatgg tgagactatt
    13681 acctcttgat aatattggga aagtagacta aaaaataaga gactgaattg gtaaagttta
    13741 ttttacaaat ctcagtctct ttttattttc ttaaattaca aatatttttt tactaaatat
    13801 cttttgattc tgtaataagt cttattatat cacttgcttc ttcattaaaa gttgttacta
    13861 tacttaggta gtctgttgct ctactcatag ctaaataaac cttatttaaa tctcctacaa
    13921 agtcatttac ttgataatct tgttcaatat catttatagt ttgattgtat aacatctcta
    13981 attcacatac tattaccgct ttatactcta aattctttat tgcatatata tttgctattg
    14041 tagttcctac cttcttactt atatttgtca aattatcttc tgcacatata taaggaattt
    14101 ttgcctcttc caatgctttt tttaacatat attgaaagta aatggttttt ccacttttta
    14161 atttcttctt attgtaagga taaacgatag caacttcaga ataatcaaga ccttttttac
    14221 ttattaaata ctcaatttcc cagattacag aacttatttg gtcatcaagg tcacttactt
    14281 ttattatatc aacagactta tttccacctc taagtgcttt agtataaaag aaagtactaa
    14341 attctgtatt tggtcttaat tcgttgatat atgagttaga attatttgaa aatttatttg
    14401 taaaatctac aatctcttta gcttgtctat aatttttact taagataatc ttatcatcaa
    14461 attctatacc attatataat tttttaaata tattcaatct attagagata ttcaaggagt
    14521 tacaagaaca cacattaaat atgaattttg ttttatataa aaactccctt ataaaatcta
    14581 tttcatactc taaaaagctt tctgcttcat caataaaaat agccttgaac atatttttat
    14641 tttttataat gttctgtgct tgttttacaa gattattaaa ggtcttttcg taatcatttt
    14701 ttaacatgtt ataatctaca attaaattga attttttagc tagtttaaat ataaaagaac
    14761 taaatgtgtg aacttctaaa ttgttattat ctttgtataa taactctatc ctctctcgaa
    14821 gctcattgca caattgtttt gtatgtgtaa atatgactaa tttatgatgt ggatatactt
    14881 ttgctaattt tatagcccta gaaagcataa ttgctgtttt gcctatacca gaaccacctt
    14941 caataagtgt attcccatat ttaatagaaa caacatcttt aatttgaacg tcttccatca
    15001 tagttgctgt atacttatag tcatcattgt agaatgaaat ttttttaaat ttttcattta
    15061 gatgaagttt atcatttatt atatagtatt ctgaacatat gtctagtaaa aataaattta
    15121 agtttatttc atcattctca tcattaagat attcctccag cgaaccctta ttcattatat
    15181 cttgaagctt atttttatct attatattat tattaacaaa ttcttcaaat tcatatgttt
    15241 cctcaacttc aacgtatggc ataatgtaaa cgtagttata acttatattt ctattctttt
    15301 gtcccatttt tagtttcaaa agttcatatt cctcattcat aacttcaagt aactcttctt
    15361 ctaaaataaa aaatatatct tctgttgtat ccataaattt tataaataaa attcttccat
    15421 ctttaacata caacaaatcg gtatttattc ctttaaaagg agtaactttt ggcactactt
    15481 taacgtcctc attgatattt tcgtaaaata ttttctcgaa ctccttcaat tttagggcgt
    15541 ctaactgaga atttatattt atgtattggc tcacttacat tacctccttc tgttatactt
    15601 aattatacca ttttgaacta tatttttata tatacttttt ataggcaaat ttagtaaata
    15661 aattcaaaat aaatacaaat aaatacaaaa ctgctaaaaa aattttgcaa taagtataga
    15721 tatttattgt tataaaatac tttctgtaaa taataaaatg ataaatttca taattaatgc
    15781 ttaaaataat aagtaaagtc ttaaaaaaaa taaatcttgt tagccaaaaa taagatttat
    15841 tataaaaaat ttaaaaacct actaaaaata atctattttc attagcaggt tttatttata
    15901 atcttcttat attaatacta ttatatccta tttttagatt ttactgtagt atttactatt
    15961 tattttgtag taaagtattg attttacaac ttcattatat caaacaaact tggataatta
    16021 tataaataat acatatataa agctttattt tattaatctt ttgtaagtag cacttttagc
    16081 acttagatta tttttgcatt atataaaatt aaacttaaac aatttaaaag ccacaagata
    16141 tattatcata tcttgtggca aatttaaatt tctaaaaata ttttcttatt atttagatat
    16201 tatttctttt acttcgcata ctctatagct cttgtttctc ttattatgct tacttttatt
    16261 tgtccaggat attcaagttc atcctctatt ttcttagtca tatctctagc caatagatgt
    16321 atttcttcat catttatagc ttctggtttt accattattc ttatttctct accagcttgt
    16381 atagcaaatg atttttctac accttcatat gaattagcta tttcttctaa tttttcaagt
    16441 ctctttatat atgcttctaa agtttctctt ctcgcaccag gtctagcagc tgatattgca
    16501 tctgctgctg taactaatac agcctctact gtttgaggct cgtaatctcc atgatgagta
    16561 ctcatggcat gtataacttc tttagactct ttataacgtc taagtaaatc catacctatt
    16621 tcaacatgtg taccttccat ttcatggtct acagccttac ctatatcatg taataaacct
    16681 gccctcttag ccaatctaat atctgctcct atttcagcag ccattatacc agctatatga
    16741 gcaacttcta tagaatgttt aagtacattt tgtccataac tagttctata gttaagtcta
    16801 cctaataatc ttattaattc cggatgaatc ccatgtacac tagtttcaaa tgcagcttgt
    16861 tcaccatatt cttttataat attgtcaact tcttttctcg ccttttcaac catttcttca
    16921 attctagctg gatgtattct tccatctgct attaattttt ctagagcaat tcttgcaatt
    16981 tctcttctta ttggatcaaa tcctgataaa attacggctt ctggagtgtc atctattata
    17041 aggtctatac ctgttaaggt ttctaaagtc cttatatttc taccttccct acctattatt
    17101 ctacctttca tttcatcatt aggcaagctt actactgtta cagtagtttc ggctacgtga
    17161 tctgctgcac atttttgaat tgcatatcct ataatttctc ttgatttctt atcagcttct
    17221 tctttagctt gactttctat ctcttttatc attatagaca tttcacgtct tacatctctc
    17281 tccgcattgg ttaagatgat ttctttggcc ttatcagaag taattcctga tatactttct
    17341 aatttttcta actgttgagt ttttattact tcaacttctt cttctttctt ttccactacc
    17401 tttaattttt cacttaggtt tacttcttta gattctaaat tttgtaattt tctatctaag
    17461 acttcttctt tttgtactac tcttttttca tacttttgta cttctgttct tctttctctg
    17521 ttttctcttt cagcttctgt tctccactta tggatctctt ctttagcttc tagtaatttt
    17581 tctttttgta ctgtttctga gtcgtggtgt gctttatcta ttatttcttt ggccaagttt
    17641 tcagcttgtc caatttttgc ttcagatata ttttttctaa caaaatatcc agctataata
    17701 ccaacagctg cacctattac aatcattact acactatcta tgacatccac ctccttcgtt
    17761 aataatccca aaatgtcatc actatgatta aaaaatattc ctaataatta aaattaaatt
    17821 tagatatttt atcctcactt aattttataa ttttttcaac attgtgtcaa gctaataggg
    17881 agcgtggcat gtctttaatt actagttatt tttttgtatt tttacttatt cttctacaat
    17941 ttcttttgat actgaaatac ctgattcttc atgttcttca tttaaattgt aaaatgctct
    18001 aactttctca tctatttcag tagttaaatc taaattatct tccaagaatt ttttaacatt
    18061 ttctcttcct tgtccaagtt tagtatcatt gtaactatac catgaacctg attttttaac
    18121 tatatctaca tcagcagcta tatctaaaag gtctccaatt tttgaaattc cttctccata
    18181 cattatatca aattcagctt gcttaaatgg tggtgctact ttgtttttaa caactttaac
    18241 tctagttcta ctacctataa ctttatcacc ttgttttatt gtatctattt ttctaacatc
    18301 caatctaact gatgaataga attttagtgc acgtcctcca gtagtagttt ccgggtttcc
    18361 aaacattatt cctactttct ctcttaactg gtttataaat atagcaacac aatttgattt
    18421 tttaattgaa ccagttaact ttctaagtgc ttgtgacata agtctagctt gtaaacctac
    18481 atgagaatca cccatatctc catctatttc agcctttgga actaatgctg ctactgagtc
    18541 tattactatt atatctatcg ctccacttct tatcaatgcc tctgctatct ctaaagcctg
    18601 ttcacctgta tctggttgag atattattag gttatcaaca tccacaccca aagcttttgc
    18661 atatactggg tcaagtgcat gttctgcatc tataaatgca gctattcctc catctttttg
    18721 agctgatgct acacaactaa gcgcaacagt agttttacca gaagattctg gaccatatac
    18781 ttcaactatt ctccctctag gtagacctcc tataccaata gctatgtcta aaccaatcgc
    18841 tcctgttgat ataacatcta tagacataga tgttgcttct cccaatttca ttactgaacc
    18901 tttaccaaaa tctttttcaa ttttacctaa agcttcattc aacgctttta atttttcttg
    18961 atctacactc atctctatac catcccttca tttatctaca aacatttgtt ctcttgttat
    19021 atattaatta tataacataa atcaaaccta gtcaatttaa aaacgctact aatgattata
    19081 tttttattca ttacatttta tttataaacc attattaata attatataca caaaagaaaa
    19141 tattcttaaa atgaaaagag gtatactata atagtatacc cttttttaca tttttaaaat
    19201 tttaagttgt tattttttat ttattaatca ttagttttta tttattaaag cataattttt
    19261 tacttagaag acataaaaag ctctttattt ttatatagat attcccatcc agaatataat
    19321 gtaagtagtg tagctataag aatgagaatt tcaccaatat ttaatatcaa tacattttca
    19381 aactgagcac ctaacaataa aaacactata gataccattt gagttatcgt tttaagtttt
    19441 ccactgtttc cagcagcaat tacttttcca tcagcagcag ctatagctct taatatgcta
    19501 actgtaagct ctctagccac tattataatt accatccaac tacttacaag atggtcttct
    19561 atcatacatg taagtgctga aataaccaat aacttatctg ctaatgggtc cataaatttt
    19621 ccaaagtcag tgactagatt gtattttcta gctatttttc catctaaagc atcagtaatt
    19681 gaagctatta taaaaataat acaagctatt aaaaatttat ttggtacatt gagcaacata
    19741 attaaaacaa atactggtat taaaaatatt ctaaacaaag ttaacttgtt aggcaagttc
    19801 atataaaaca tctcccatta aatcgtattc cattgcatca tttatttgaa cacttacaaa
    19861 ttctcctact tcaagattgt ctacactttt tacatacact atactgtcaa tttcttctgc
    19921 atcaccttgt gttcttcctg tatatacatt atcttctatc tgttcttcta ttaacacctc
    19981 ataagttttt cctatctttt tgtcattaag ttcttcagat attttttgtt gaatcatcat
    20041 taaagtatct cttctttgta tttttacttc ttcatctata tggtttggca atctatctgc
    20101 tggtgtatct tcttctcttg aatatgcaaa tgcaccaagt ctatcaaatt taacctcttc
    20161 aacaaagtcc acaagttgtt tgaagtcatc ttctgtttca ccaggaaacc ctactattat
    20221 tgtagttcta agtatagcat ctggtatatt acttcttatc agattgattt tatttaatat
    20281 atcttcttta gtagtttttc tattcattaa ttttaaaata ttgttacttg catgctgtat
    20341 tggcatatca aagtaactac atatattatc atatttcttt ataacttgta tcaattcttc
    20401 tgttatagat tctggatatg aatacataac ccttatccac ttaaatccat ctatttttgc
    20461 aagttcttct aaaagttctg ataatctttc ttttccatat aaatcaaaac catactttgt
    20521 cgtatcctgt gctataacca caagttcttt tactccagat tcagctaatt tcttagcttc
    20581 tttaattata tcttcaaatt ttctacttct atatttacct cttagttttg gtattataca
    20641 ataagtacaa ttattggaac atccttctcc aatttttaaa taggccatat agctaggtgt
    20701 agatatatat cttggtaaat cttcattaaa tacaaactct atatcattaa ggcttacaat
    20761 ttgatgcatt tcacttaatt ctttaagtat tttatctata ttttgatagc ttcctgttcc
    20821 tactatagca tctatttcag gaatttcagt ttttaattct tcagaatatc tttgggctag
    20881 acaccctgtt actatcaaca acttcaaatt gccagttttt tttaactctg caaagtttat
    20941 tatcgtatct atagattctt gtttagctga ctctataaac ccacatgtat ttactataat
    21001 tacatcagct tcttcaaaat ctccaattaa tttatagcct ttgttattta aaattcccat
    21061 cattatttct gcatctacta aattttttga gcatcctaat gattccaatg ctatttttaa
    21121 cattcacttt ctccttccaa tatactctca tataagtcta taacatcttc taaagctttt
    21181 tgtgtatcat taaaatttat aatcttacta tacttatatt tctctactga atgcatataa
    21241 agtgggtcgt agtattctaa aagatatctt tttacaagtt ctttatattc acctgattct
    21301 aataaatcaa tataatcatc tactacttta ttacccaatc tttttctaaa cttgtttata
    21361 cattctttta aaatcaatat attaccttca tctttatcat aaatataatc tctacaaagt
    21421 ctatcaactc tattttcaat atcacattct aataatatat gatgtccttc tcgtgtcatt
    21481 gcctcgaaaa tttcatttgg aactgtaaca cttccaactc gtttgctttc actctcgaca
    21541 aatatataat tctctttcga aaaaaatata ctttcaaata gttttgtttc aaagttcttt
    21601 tgagatggtg gctttttatc aaaagttata aaaccaaagg tagaaccact gtttttagct
    21661 atgccttcta aatccagcac gtctattcct ttttcatcta ataaatgtaa caaatcagtc
    21721 tttcctgtac cagtcaatcc atgaacagat acaaagtttt ttgtatccat tacatgcctt
    21781 aaatactcta aaacaaaatt tctataagcc ttatatccac cttcaagttg atatacattt
    21841 acacctaatg atgataataa atttactata ctgccacttc tcattccgcc tcttgcacaa
    21901 tatatgacaa tattatcata atttaatgca agttctgctg cttgtaaata tatatccttt
    21961 aatttatacg atacatagtc aaatcctttt tgtattgctt catgttttcc ctgcatctta
    22021 taaattgttc caacttcatt atgttcatta tttttaaaaa gaggcatatt gattgcattc
    22081 aatatatggt cttcttcata ttctccttca gttctcacat ctacaaatat tactttatct
    22141 agcttaagtg ctttttctat ttttataact gacaattcta ttcaccttct aaattctgca
    22201 aatcctgttt gcttattaat acctttctcg gtttacttcc ctcacttgct ccaattattc
    22261 ctctttcttc catagaatct ataagtctag ctgctctatt gaatcctatt ttaaatcttc
    22321 tctgtagcat agaggcagat gcttgaccac tttccacgac aaattctatc gcttcactca
    22381 aaaactcatc ctcatcacta ccctttgaag tattaacctt agatatagtt tcaattatat
    22441 cttcttcata ttttattcca tctttaacct gactttttac aaaatcgatt actttttccg
    22501 actcactctc tgatatgaat gccccttgaa gtctaactgg ttttgctgca ccaagtggat
    22561 agaataacat atcaccttta cctagaagct tctctgcacc acccatatca aggattgttc
    22621 ttgaatcagt ttgagatgat actgcaaatg ctattctaga tggtatatta gcctttatta
    22681 cccctgttat aacgtcaaca gatggtcttt gagttgctac aatcaagtgc attccagcag
    22741 ctcttgccat ttgagctaat ctacaaatat aatcttctac atcatttgca cttgccatca
    22801 ttaaatctgc taactcatct attattatta ctattttagg aagtttttct tccgctttct
    22861 cattataact tgttacatct tttacttgag catctgcaaa taatttgtac cttctattca
    22921 tctctgtaac tgcccaattt aaagcatttg cagctttttt agggtcagta actactggta
    22981 tcaatagatg tggtattcca ttataatttg caagttcaac tacttttggg tctattaata
    23041 gtaattttac ttcatcagga tttgccttat ataaaatact acttattaat gtatttacac
    23101 acacactctt tcctgaacct gtagaaccag ctattagtaa gtgtggcatc ttacctatat
    23161 ctccaattat aatttttcct gctacgtctt ttccaagtcc cattgcaaga ggagagttaa
    23221 aattattaaa ttcttcactt tctagaactt ctctcacacc aaccatttga gcttcttcat
    23281 ttggaacttc tattccaatt gcacttttac caggaattgg ggcttcaatt cttatacttt
    23341 tagctgctaa acttaaagct atatcatcag ttaaatttac aattttactt accttgactc
    23401 ctggacttgg ttgtatttca tatcttgtta tagtaggtcc aactgtaact tgattaattt
    23461 ttgcttccac tccaaaatct gatagtgtct tttctaaaag agaagcattt ttcaacactt
    23521 tctttttacc attttcatca gacttcttat ttactttatt taaaagctca atgctaggct
    23581 ttttatagtt tgaataatcc tcattaactg gctctgctac aatactcata ggttgagttt
    23641 tttctatatt taaattaggt ttagctatat caactttttt ttctggttta gtatctacaa
    23701 ctggattttc attggtagct ttttgtaatt cttttaaaac atctaactct ggcatacttt
    23761 gagttccttc taatatttct aaatactcat cttctgcctt attaaatcca actattttta
    23821 tagttttatc atctacacca tcactatttt cttcttcaaa atattcatct tcttcatcat
    23881 cattattaag accttttgac attaaccctt taaagaaacc tggtttttta tttatagtag
    23941 tatcatctac ttcatcagtc atcatatcta ttgcagattt tttcatattt gcaattttat
    24001 ctttaaacgt taaattgctg tctttagatg ctttagattt tgattttgca tttgacacca
    24061 aatcttttat agaaatatta aatataaaca ttacagaaag tataagtgcg aagatactta
    24121 ttaaccatcc acctgctata ccaaatattt tactcatata atacgcaata gttgttgcta
    24181 tcaaaccact accttgtcca cttacaccca atttcataac atcatcaaac atgttacctt
    24241 ttagtgggct atctacagga agagttcctg catttaataa tccataaaat acaaatataa
    24301 ataaaataat tatgtagtat agtttagtct ttcttagcct atatatatat tcatttccat
    24361 caaaaaatcc taaaagtcct gttataatta ctataaatgg tattgctatt gaaagccctc
    24421 caaatagtcc cttaaaaaga ttttgcatta acacaggtat ccatcccata gaattagaat
    24481 ttaaactata taataaaaat acacctataa atattgttat taaattatga tattctgcat
    24541 taaaacttaa ggtatttacc ttcttttttt tcttcttttt cgtggccatt aatatcactc
    24601 cttattttta gcaagtttta ccccttcaca gcaaaaagtg ctaatgcctt aacactaaca
    24661 ctcctacttt attacatcat tatatcataa attttattat ttaaacaaat tttaatcatt
    24721 atttttttct tcctcagatt cttttataag ctctcttaat tttttaagtg cttcttttag
    24781 tcctccaact tcatctataa gaccataatc cacagcttct tttcctatta atacactacc
    24841 aacatcactt acaagttcat ctttttcatg cataagtttt tcaagtacat cttttttgat
    24901 atttgatgtt cttattataa attgaattat tctatcttgc atctttttaa aatattcaaa
    24961 agtctcattt ataccaatca caagaccagt agttcgcact ggatgtataa tcatggttgc
    25021 tgttggtgct ataaatgagt aatctcctgc tgtagcaaga ggaacaccta tactatgact
    25081 tcctcctaga acaagagtaa ctactttttt agatgtactg tttaaaagtt ctgcaatagc
    25141 taaacctgct tcaatatctc ctccaacagt gtttaaaaca actaacactc ctttaacatc
    25201 attactttcc tcaattgagt atagcattgg aattatatgc tcgtactttg tagctttttt
    25261 ttgaggattt cctataaaat gtccctcaat ttctccaatt atagttatac attgaatatc
    25321 tttaggaggt tgaggtggca tttcattggt accaaattgc tttatacatt ctctctcttc
    25381 gcaactagat tcttcactac aattatcttt atcaaatttt tcattatctt ctctataatc
    25441 tttcataaaa aaactcctat caaaattata tttaatttag ttttaccaaa taaatcaaat
    25501 atattaagat atatatgaaa ttcttaaatt tgattaaaaa ataattgtat tatacagttt
    25561 attttaaata aaattgttgg tgtatagcat gtactgctgt atgcatatct tcttcactaa
    25621 ctaaacaaga tatagtcata tttgagtctg atgtttgtaa aagagatacc cctgcttttg
    25681 ataatcctct aactaccttt gacatgatac cagacatttc atcagcaatt cttgaacata
    25741 tcaatgttac cttagcacag tctctattta cttcataatc taattcaaat ttatctagta
    25801 tttcctttaa tgattttata tcagcatctt ctacaacaaa tgctttttct gatataaaga
    25861 aatttatcat atctatagtt ataagtttct tttctatctc atttaatact tctgtaaaca
    25921 cttcttctgc tgacttaatc ttaacttgtg ctacgctatc tttatttgca acagcaacct
    25981 taaaatctct ttcttgttca tattctatat tgtcttctaa gtgtctacat aaagaaccta
    26041 tttttgtacc ttcaaaagtt ggattcattg tattctttat ggctaaagtt atatttccac
    26101 ttttagccaa ctgtactgct cttggatgta ttacttttgc acctttgtca gccatttgga
    26161 atacttcctc atagtctata aaactcaata ctttagcgtt tggttctact ctagggtctg
    26221 cagtcattat accatccaca tcagtgtaaa tttcaactgt ttcacattct aaagctttac
    26281 caatagcaac tgctgatgta tcgcttccgc ctcttccaag agtagttatt tctccatcat
    26341 ctgttacacc ctggaaccca gctataacta caaccttacc atcatctaaa gctcttttta
    26401 cctttttagg atttatatac tttatctttg cattagaata ttcatcactt gtaattatac
    26461 ctgcttgctg accagtaaag aaaacagaat ctatcccctg tgcattcaat aaattagcaa
    26521 gaattgttcc tgatattatt tctccacaag acattattaa atcaagttct cttttacttg
    26581 gctcatcatt tactgcacta cacaaattta taagtgtatc tgtagcatat ggagctcctt
    26641 ttcttcccat tgctgaaact actaatacta attgtaattc ttcatcattt tttttgtatg
    26701 cttttactat cttacatact tcattcattt tttcatatga ttctactgat gtcccaccaa
    26761 acttttgcac taaaatactc attttttcct cctaaatata tccctcatat tctataatta
    26821 tcatgtcatt acctattttt tttacatttc tccatggtac ttctaaaaat gacttatctt
    26881 ttcttctggc aaaaaatcct ttttcttttg gaattagaag cgctaatata tcgcctgtag
    26941 tttcatctag tataaggtca cattctccaa tgacccccaa tctttctcct gtgaccaagt
    27001 taactatttc cttacctgct atttcagata aattcatatt ttatacctcc agagatttac
    27061 ttttttcaat attaatccaa gtgtagaatc ttttctacat ctcttccaac tatacatgta
    27121 ccaatatttt cgatattgaa taccttatca acaaccttct ttattgaatt aatattaaca
    27181 ttatttatac attcaagtat ttcatctgta gtttttactt ttttgctaag taacatagat
    27241 ttaccagtag acatcattct actgctagta ctttctaaat ccaatatata atttcctttt
    27301 aactgttcct tgctttcaga tatttctttt tctgtaagat agttttctct tatattttca
    27361 atttctttct ttattaaatt atatacatct tgtaaatttt ctgtactcat gcttgcaaat
    27421 atacctaatt caccacattt cctatataat gtctgtgatg agtatattga atatactaaa
    27481 cctttttctt cccttatttt ctgaaaaagc cttgagctta tacttccacc gaaaatatta
    27541 tttaccactg ccattgaata gacttcttca tcattttcaa aaggaatacc ttttaggcac
    27601 atagctaagt tcacctgttc agtatcttta ttttttgata taaagcaagg attaaactta
    27661 gcctcactta tgtctatact taaatttttc ttttcccagt gtccaaattt tgatttgatt
    27721 ttctccacca tatcatcaaa gttaaagttt ccagctatag aaataacagc gttatttgga
    27781 atataatact tatttaagta ttctaacatg gattctctag ttatattgta cagagattct
    27841 tttgtcccaa ttatattcat tcctaatcca tcattagcat atatattttc cactaataaa
    27901 tcataagata agtcatctgg agagtcttca tacatcttaa gttcttccaa tattataagt
    27961 ctttccttat ctatatcatt tttatcaaat ttagaattta gtatcatatc actcaataca
    28021 tcaattcctg tatctatatg ctcatctatt agttttacat aataacatgt acattcttta
    28081 cttgtaaatg catttatttg accacccaaa ttatctattg aactagcaat ctcttttgat
    28141 gttctgtttt tggttccttt aaacatcata tgctctataa aatgagaaat tccactcacc
    28201 tgtgcttctt ctatcctaga gcctgcattt atccaaatac ctaatgttat tgactttaga
    28261 tatggtattt cttcaccaat tattgtaagc ccattttcca gtatttttgt cttatacatt
    28321 acattctcct aacaatttat tctttgtttc atattggatt attgaaaaca ctatgtttta
    28381 attatattta ttttttatat gtattacatt ataagtcagt cttttaatta attcaactac
    28441 aacttataca atcttaacca aatatttata ctttgtctac ttaaatacat cactaagttt
    28501 tcctggtttt agtccttttt ctcttacaat agctataata tcatctatac attttgtcgt
    28561 tgcgttggtt ggatgcatta aaattatact actatcttta atgtcttttt tcttcattct
    28621 atcaatgatt acctctggtt ggtctttgta tttccaatct atagtatcgg catcccattt
    28681 gatagaagta taccctaatg ctttagcagc ctttactgtt tctggaccaa aagaacctgc
    28741 tggtgcttga aaaaatttag ttttttcacc tataatttct tcaattatct ttttagaggt
    28801 ctctatttgc tcataattgt cttcatatga taatgtagaa taatctaaat gtttgtatcc
    28861 atgattacct atttcatgtc cttgtttttt tatctttaat aattcatcct tattcttttc
    28921 tgcccatttt ccagttacat taaatgtaat ctttacattt tcttttttaa gtgtttctaa
    28981 aatggattct acgtactctg tttcccatcc aaggtctata ttacaggtta atgcaacata
    29041 tccactttta tcctttgtac ctctttcata tggtaaatct acaccattaa ataaattaaa
    29101 tactggcttg ttgttaaata actttaatac cattacccct cctgataata ctaataacac
    29161 tactaaaatt agtattatga tttttttgag cttactctta ttaagtacca tcattatcat
    29221 taaaactccc cctaattatg tacaaattgt ttcttattta atactattaa aaataagctc
    29281 tgtttatgca ctaaatataa cttaagtgat tctatatata tcaataaagc tctctattaa
    29341 tcagctttta aatagcttct ttataagagt aaagcctgac agaaaaagaa ctataagcca
    29401 tccataacta tcattttaaa attatctact tttttgtatt taaaaaagca aaatcctaag
    29461 actttgcttt taattatata ataagttatt tatttttatg ttctggtttt ggtaaaagaa
    29521 cttttcttga taaattaact cttccttttt catcaatctc tgtaacttta acttcaactt
    29581 catcccctat attcaataca tcttcaactt tggcaactct ttcatgagct atatgagata
    29641 tatgaagtaa tccttctttt cctggaagta tctcaacaaa tgctccaaag ttcattattc
    29701 tacttacctt acctttataa gtttttccta cttctggttc aactactata ttatttataa
    29761 gttcttgagc tttcttaatc atatcaatct caatacctga tataaatact tccccagttt
    29821 gttcaatatc tatcttaact ccagtttcgt ctattatctt agttattatc tttccaccag
    29881 gtcctattac atcttttatc ttgtcaggat ttatttgcat tttaacaatc ttaggtgcat
    29941 atggtgaaag ttctggtttt ggctgagata tagtttttct catctctcct agtatatgga
    30001 ttctaccctc tttagcttgt tttaaagcac gttgtagaat ttctttatct ataccatcaa
    30061 tttttatatc catttgtatt gctgttatac catactctgt tccagctact ttaaagtcca
    30121 tatcgcctaa atggtcttcc ataccttgta tatctgaaag cactgcaacc ttaccatcat
    30181 gctttataag tcccattgct atacctgcaa ccatatcttt tataggtaca cctgcatcaa
    30241 gtaaagataa tgttgagcca catacacttg cttgagatgt agaaccattt gaacttaata
    30301 cttcagaaac taatctaata gcataaggaa attcttcttg agatggtatt actggtaata
    30361 aagctctttc tgctaaagca ccatgtccta tttctcttct tcctggtcct cttgatggtc
    30421 tagcttctcc aacactatat gcagggaaat tataatgatg catatatctc ttgttttctt
    30481 cttcatctaa cccatctagt ttttgaacat ctcctaaagc acctaaagta gcaacattaa
    30541 gtacttgagt ttgtcctcta gtaaatatgg ctgaaccatg agctctaggt atcatgccag
    30601 tttcacacca tataggtctt atttcttcaa gttttctatt atctggtctt acattttcat
    30661 gtactataag ttttcttact tcttctttta ttatatcttg taatacttct tctatatctc
    30721 caacaaaatc ttcaaaatct tctaaagttt cttcaaagtg agctaaagtt tcttctttaa
    30781 ctctatccat attttccatt ctctctaact tttcaaaagt ctgaactgct tttttcatct
    30841 tatcagttgc aaattcgcga accaattgag ttatttcttc tcctgcatgg tataattcaa
    30901 caggcatttt ttcttttcca acttctgcaa ctataccttc tataaactca actatttttt
    30961 ttatttcttg gtgagcaaat aaaatagcat caagcattac ctcgtctgga acttcatcag
    31021 ctccggcttc aaccatcatt attgcttcct ttgtacctga aacaactaga tgcattgaac
    31081 ttttttctct ttgctctgcg tttggattta caacaaatgc accatctaca aggccaacac
    31141 atactgaacc tgttggtcca ttaaatggta tgtctgatat agaaagggct attgaagaac
    31201 ctatcattgc tactatatct ggtgtacaat cttggtctac tgatagaact gttgcaacta
    31261 cctgaacatc atttctaaat ccttttggga ataaaggtct tattggtcta tctatcaatc
    31321 ttgatgtaag tatagctttc tctgaaggct tgccttctct ctttaaaaaa cctccaggta
    31381 tcttacctac agagtataat ttttcttcat aatccacact taaaggaaaa aagtctattc
    31441 cgtctctagg tttggctgat ttagttgtat ttaccattac catactatca ctgtatcgaa
    31501 ctatacaact accactagcc atttcacaaa tctttcctat ttctacagaa agttctcttc
    31561 ctgcaaaatc cattttaaat attttatgtt caaacattaa tgcttgtcct cctcttatta
    31621 aaaaacacgt atatcactct atttactata ttatcaaaaa tactataaat taacaatata
    31681 aaattatctt cacatatata tgcaaaaacc ttatattact actaattaga acaacttata
    31741 gccaatatat ctggccctgt atgagagcaa atagaaactc ctcctcgagt aaataatact
    31801 cttcttgctt ttattctttt atttacttca tcttttaata tttcacaatc gtgtaaatta
    31861 tctccacaac ctattgtgac gatttttcct tctaaagacc cttcattcat ttctaaaatt
    31921 atatcgacca atttacttgc tatattcttt attcctctaa ccttatttac caacttagct
    31981 tccccattat caaagaaaaa tataggcttt atatttaaca tatttcctat caaagcagtt
    32041 gcaactggaa ctcttccact ctgctttaaa aaatcaagtg tatatggtgc aaaaagcaat
    32101 cttacactac tgcgagtatt ttctaattca tctataattt cttcaaatcc cagtccttct
    32161 tcaagaagtt cacatgcctt tataacatat tgtccactac ctagagataa atttctagta
    32221 tcaaatatat gtattttttc attttcattt acatcatttt tagctatcat agcactttga
    32281 aaagttcctg atgcgtttgc agcccctgtc atacagatta tatgataacc ttctgttatg
    32341 aacttatcaa acacttcttt aaactccata tatgtagctt gtgaagtttt aggtatttgc
    32401 ttgatttctt ttactttttt ataaaactct tctttcttta tatctactcc ttctatatat
    32461 tccctatcat taaaaataac tgtaagtgga actatctcta tataatcttt ttctgatatt
    32521 tcatctggaa tatcgcacaa actatcgcat actaacttta ttttcaaaat aatatcctcc
    32581 ttattccaac taattatcct gttataaaat ttctatattt atcctgtctt tccttttaaa
    32641 ttgattatgt atttgtatac tattttaata ttcttaccca atattattca ttttataatt
    32701 ttttataaca tataaactac ttttattatt aactatttta ctttataatg aattaactat
    32761 aaaaaagcag gtatacacta tacctgcttt tttataaaga atgaaattac tttcttaatc
    32821 ctaatttagc tattaatgct ctatatcctt caagatcttt ttcctttaag taagctaata
    32881 agtttcttct tctaccaacc atttttaata gtcctcttct tgaatggtgg tctttcttat
    32941 gagtttttaa atgtccattt aactcgttta ttctagctgt taataaagct atttgtactt
    33001 ctggagaacc agtatcccct tcagctcttc catattcttt tattatttct gatttgttta
    33061 tcatttagat tacctccgta tttttttaga aacgcctatt actaagcatt gattggagta
    33121 ttcaaatgct gagtaatggt tattttcctt aatcatttta tcatacatta cttgtttttg
    33181 caaacatagt tttcatacac ataatttgta tcattataca attgattttt taagtcatct
    33241 attgaattaa actttctttc atctcttatt ctttccaaaa attcaacaat tatattttcc
    33301 ccataaatat ctctatcaaa ctctaaaata tttgtttcaa tagacaaagt ttttccatta
    33361 actgttgggt tatagcctac atttgtagca ccaaaataag tctcatctcc aatatgtaca
    33421 atagaagcat aaatacctct ctttggaacg agcatattat tcttaaggtc aatatttgcc
    33481 gttgggaatc ctatagttct tccaaggtgt ttagaatgta taacacaacc ttctaacttg
    33541 taatttctac ccaaatattc cttgacatta gccatatcac cctgggatac taaacttcta
    33601 atataagtac tactcactct tacatcattg attttgatgg gttttattac ttctacctca
    33661 aaaccaaatt catgttctaa gctttttaat agattaacat tgccttcttt tgcccttgca
    33721 aatgtaaagt catgtccaat tactatcttt ttagctttta atttttttac tagtatctca
    33781 tctacgaaat cctttgcagg tattttagtc atatactcat caaatggtat gattacaact
    33841 atatctattc ccaaatcttc taataatttt attttatcat cattgcttat aatatttttt
    33901 gttgagtttg gtctaaagta atttacagga tgatttgcaa atgtaaatac gatactctgt
    33961 atattttctt tttttgcatg ttcaactgtt tttcctataa gaacttgatg tcctttgtgt
    34021 acaccatcaa aatttcctat ggtaatgaca ctttctttta tgtttgctat ttcttttata
    34081 gattttataa tcaccataat aaatgttccc cgctaaaata taatttactc ttaacttatt
    34141 cacaaactat tatagcataa gtaaaagaga tagactatag aagttattat agtactatct
    34201 cttttgttgt ttttttaaat acattggtta tatgaacatc ttatcacttt taacacttat
    34261 tgtattattg tgttttgata attttcctaa tcctaagaaa ttatctgtac tgtatactct
    34321 tacaaattca tcatctttat cgaaattatt ttttaaaaac cttttatcat ctattgagcc
    34381 accattacta taatatttta tagcattagg gtttaataca acataattaa acgaatcaag
    34441 gacataatct atatcatata agtatttgtc taaagtttta ttttcataaa ataattctaa
    34501 ttcttctaat gttattgaat tatctaagtc aaatttacca gaagatgttc tattcaaaaa
    34561 cgacatatga gctccacaac ctagatattc tcctatatca tggcaaatgc ttctcacata
    34621 agtcccttta gaacactcaa cataaaacat tactttatta ccttttatac ttagtatttt
    34681 tatgtctttt atatttactc ttcttgtttt taaagtaatt tcagattgtc taccacttct
    34741 tactaaatca cacattctct ttccatttac ctttaaagct gaataaattg gaggaagttg
    34801 atttatctct cctctttgtg tgtcaaaagc tctttctatg tcttcattac taaatttaaa
    34861 atcatcaact ttttttaaaa tttcacctga agcatcataa gtatctgtac ttatacctaa
    34921 agtaagctca catatatacg atttatcttt gtttaaaata acttcacata cttttgtagc
    34981 tttccctata cagattggta aaacacctga agcatctggg tcaagagtac ctgtatgacc
    35041 aacttttttt atatttaaaa tctttctcac tctacttaca acatcatgag atgtcatacc
    35101 tgtgggtttc aatatactta taatcttatt cattttactg tcaccttaaa ttgattttaa
    35161 cactgcctct agtaccattt tctttgcatt atcaatacta tctctaatag tacatccagc
    35221 agcccttaca tgaccaccac caccaaataa cttggctatt tcacttacat caacataatt
    35281 ttttgaccta aaactcactt taatttcatt ttgttttttc tctttaaata aaattccaac
    35341 ttctatacct tttatgtctc ttgtatatgt tgttattcca tcaacatcat taaagctaat
    35401 attatttcta ttcatcatgt cttgagttaa aactatacta gatacctttg actgaacctc
    35461 ccatgactaa agtcacaggg ttcctgcttc acagaatttt gcatattaaa atatgtctta
    35521 ctaattctcc acaggctatc cccgtagttc ctacggttct tacataagtt atttattttg
    35581 aatcgttatt agtcttaatc cttcttttaa tatatttata cttgcattta tatctctatc
    35641 gtgagtttca ttacaactag gacaaatcca ttctcttata tttaaatcct taacttcctc
    35701 gtttttatac ccacatttat tgcatatttg tgaacttgca aagaatttac ctacctttac
    35761 aatttttcta ccataccaat tagccttgta ttctaattga cgaataaatt ctgaccatga
    35821 tacatctgaa attaagcgag atagtttacg atttctaatc atattcttta cttgtaaatc
    35881 ttctatgcaa ataatatcat tctcttttat taatttagta gatagttttt gtagaaaatc
    35941 atttctttga ttagctatat gttcttgaag tcctgcaact tttaatcttg ctttatttct
    36001 atttaaacta ccgattgttt ttctcgataa ttctctttgt aatttagcaa gcttgtttaa
    36061 tgacttctta agatacttag gattttctat aaagtctcca caacttgaga tacaaaattc
    36121 tttaattcct aaatctaaac ctatatgatt attagtattt tcaaatactt caatatctac
    36181 atcagtacag cataatgata cataatatct accacttggt tctttagata tagtagcatt
    36241 aagtattcta ccttgaggta cttgtttatc ccttatctta accataccaa gtttaggtag
    36301 ttttatatat tgaccacaat acataatgtt tccatttgta aagttagttt tatatgaaaa
    36361 tctattaatt ttctttgatt taaatttagg aaatcctgcc ttttctttaa agaatttttt
    36421 atatgcatta tctaaatctt ttaaggcgtt ttgtagtgaa aatttgtcag gttccttaag
    36481 ccattttaat tcttttttta aattggtcaa atcagaacta cactgtttat aagtaaaagt
    36541 ttctttatcg cttttataaa catctattct tttagcaaga tatttattat atacaaatct
    36601 acaacatcca aaagttttgt taattaactc ttgttgtttt ttatttggat acattctaaa
    36661 cttata
//
LOCUS       DAEPKC010000032        35231 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.032, whole genome shotgun sequence.
ACCESSION   DAEPKC010000032 DAEPKC010000000
VERSION     DAEPKC010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 35231)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35231)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35231
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.032"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(275..1879)
                     /locus_tag="KR294_001636"
     CDS             complement(275..1879)
                     /locus_tag="KR294_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH0239717.1"
                     /translation="MKAKIYYNGNIITMEDSICGDAILIKDKIIKKIGTKEEVFALKN
                     KDTEIIDLQGKTLMPSFIDSHSHLIAFATTLKLVPLEDATSFKDIVKKIQDFKESNNI
                     KKGDWIIGFSYDNNFLEENKHPDKSVLDSASSENPILISHASGHMGVANTLGLKQLGV
                     TNETRDPEGGHIGRVEGSEEPNGYLEENAFFNVASKIKQPSSNEIFNSIEKAQNIYLS
                     YGITTAQEGLMEENQFNILKAMANQNKLKMDVVGYVNLKKSKSVADNNREFIKKYINR
                     FKIGGYKIFLDGSPQGKTAWLSRPYENSDDGYCGYPIYKDEEVEKFIDISLKEKMQLL
                     THCNGDAAADQLIDAFEKVLNLKEQSSENNIRPVMIHAQTVRADQIDDMKVINMIPSY
                     FVAHTYYWGDIHIKNLGEDRAFKISPLKTTIEKGLIYTLHQDTPVIAPNMLETVWCAV
                     NRITKKGIQIGENEKISPLDALKGVTINAAYQYFEEDKKGSIKEGKLANLIILDENPL
                     TIDPMKIKDIKVLQTIREGEVLYSLK"
     gene            2265..3191
                     /locus_tag="KR294_001637"
     CDS             2265..3191
                     /locus_tag="KR294_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="HBH0239718.1"
                     /translation="MSKENKNVRIAVVQASPVIMDLEKTVEKALGLIKEAGRKGANIV
                     VFPEAFIPAYPRGLSFGFVVGSRTMEGREDWKRYYDNSVPVPSATTDLLGKAAQEAGV
                     YLSMGITERDGNDINCTLYCTNLFFSPEGKLIGKHRKLKPTGTERCIWGEGDGSTLTV
                     VDTPYGKMGSLICWENYMPLARTALYAKGVKLYIAPTADSREEWQATMKHIALEGRCF
                     VIGCNQYVEKNTYPTDLNYYKELDAEPEIMCPGGSCIVDPFGKYVAGPIFNKEEMLIA
                     DLDLEKIVLSRLDFDSEGHYSRPDVFELIVHE"
     gene            complement(3311..4309)
                     /locus_tag="KR294_001638"
     CDS             complement(3311..4309)
                     /locus_tag="KR294_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhdH/YhfP family quinone oxidoreductase"
                     /protein_id="HBH0239719.1"
                     /translation="MNKKFKSLYITEEEGNFRRNIVEREVDTLPEGEVLIKVKYSSLN
                     YKDALSANGNKGVTRKYPHTPGIDASGIVESSSCDDFKIGEEVLVTGYDLGMNTSGGF
                     SEYIRVPSSWVVKLPKNLSLKEAMDYGTAGFTAALSVYKFIDSVDKNMGDVLVTGGTG
                     GVAVIATKILIKLGYSVVVSTGKLEEQKEVLLNLGVKDVIHRSEVDDNSGRPLLRPRW
                     AGVIDTVGGNTLATAIKTTNYCGAVTTCGNAGGVDFTSSVYPFILKGITLYGIDSVDC
                     PMNLRLKIWDLLSNEWKLDDLDDMVNVVSLEELNDSIDSIMAGKHVGRTVVDLEKI"
     gene            4413..4850
                     /locus_tag="KR294_001639"
     CDS             4413..4850
                     /locus_tag="KR294_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBH0239720.1"
                     /translation="MEDKYIVHFISKTKASMIKFIENKLSKNGLGELIPTHGNILTAL
                     YENNGILTMKEIAAKIGKDKSTVTVLVNKLINLGYLERQKCTNDKRITYIKLTKKALL
                     IEDTFNSISTQVKETAYHNITENEKQEFLRILKKINDNFKNAD"
     gene            4936..5523
                     /locus_tag="KR294_001640"
     CDS             4936..5523
                     /locus_tag="KR294_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rubrerythrin family protein"
                     /protein_id="HBH0239721.1"
                     /translation="MNLKDSKTKENLLRAFAGESQARNRYNISASVAKKEGLYIIESL
                     FNYTADQEKSHAKQFFSKLKEFAGENISISGAYPVDLYDKTAQHLKAAQHNELQEWDD
                     VYKNFGKTAREEGFESIAKLFENIAEIEKVHGDRFGRYATDLEEGTLFRRNEDIQWIC
                     THCGHIHIGKEAPKACPVCLHPQGYFLDFKNSLFE"
     gene            complement(5823..6443)
                     /locus_tag="KR294_001641"
     CDS             complement(5823..6443)
                     /locus_tag="KR294_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhbD family protein"
                     /protein_id="HBH0239722.1"
                     /translation="MEELISKKDLLSKTNISYGQLYRWKRKNIIPEEWFIKKSAFTGQ
                     ETFFPRDKILERIELILSMKEETSLDDIANMFMKKDINKEFDIDFILSKEVICNYTKE
                     IFQNLYKKEQSIGKKELLILSIIEKFLVKSIITFEELKLIVNIIEENFTSIYNESGKI
                     YLFRKFGVPFVVGCLDYKKVKFEKDVVKIIEIDLTKEINDISIKLS"
     gene            complement(6451..7218)
                     /locus_tag="KR294_001642"
     CDS             complement(6451..7218)
                     /locus_tag="KR294_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polymer-forming cytoskeletal protein"
                     /protein_id="HBH0239723.1"
                     /translation="MEKGSIKILGEGFISSGEYENIKIVGSSKSKGNVKSNEVKVLGD
                     AKFEGDINIKNFVVNGKTIIRGNLKAERVRVNGQLNIEGDAEIDDLVITAQQKVDGKL
                     KCNNVTIRGQLSVNENMYAQDIKIYGEMRNKSNIECEDIKVYGAIKCDGLLNGENIYV
                     YSGGGSYCKEIGATNIKIGRSKDAFSLIKIINIFSGKFKCNLIEGDTIELEDASIKDI
                     RGKSISLVDNCDVGNIEYSDNLSVSDNSTVKNSIKVG"
     gene            complement(7259..8080)
                     /locus_tag="KR294_001643"
     CDS             complement(7259..8080)
                     /locus_tag="KR294_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239724.1"
                     /translation="MNEELSSLRFDGVGKCKGGIFDNVNISGTGKIEGSVKCSKFDSS
                     GSAKVFGTTECNEFFTSGLSKVEGNILASKVEISGLLRCTGNINSVEIDTSGIINVEG
                     SIKSDIIHGEGYLKANENIDCENINLSGILECNGFLNCEEVNISLNGTSNFNEVGASS
                     INIKKGHGDYCKKFRMLEKKHINFEKVSSNLISLGLLSIRKYTESKLFANIIEADEIS
                     LENSEVKVVRGKNIKIGKGCYVESLEYSESIEIDEDSIVGEIKNISEKIKLKKDK"
     gene            complement(8439..10349)
                     /gene="phnW"
                     /locus_tag="KR294_001644"
     CDS             complement(8439..10349)
                     /gene="phnW"
                     /locus_tag="KR294_001644"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HBH0239725.1"
                     /translation="MKKIYGEKIKAVVFDWAGTTVDYGCFAPLNVFIEIFKRRGIDVT
                     MEEARKPMGKLKIDHIREMCEMDRIKNIWSDKFGKVPTEDDVNELYAEFEPMLFETLE
                     EYTTPIPHVVETIEKLRKNGLKIGSTTGYTREMMNIVEPNAAKKGYSPDFLVTPSEVS
                     QGRPYPWMCYKNAEALGVSPMSSMVKVGDTISDVKEGVNAGMWSVAVIKGSSELGLTQ
                     EEVENMDKEELKAKMSIVSKKFKEAGAHFVIETMAELEDILIKIENETIKSDFVPEND
                     YILLTPGPLSTTKSVRASMLKDWCTWDVEYNNLVQDVRRRLVSLATQNTDKYTSVLMQ
                     GSGTFSVEAIIGSTISKDGKLLVIANGAYGKRMKDICNYLNIQFVDCTFKDIEAVDLN
                     VVENLLKENKDITHISMVHCETTTGRLNPIQEVGKLAKEYNKIYIVDAMSSFGGIEID
                     VEDFNIDFLVSSSNKCIQGVPGFGFIIANKEKLSKCKGIAKSLSLDVYAQWETMEKNN
                     GKWRFTSPTHVVRAFYQALLELEEEGSVEKRYARYKENQFTIASRLKSLGFDTLVNDN
                     AQSPVITTFLYPKNAKFEFMEFYTYLKDNGFVIYPGKLTDIDTFRIGSIGEVYPTDME
                     RLADVIEKFINR"
     gene            complement(10628..11413)
                     /locus_tag="KR294_001645"
     CDS             complement(10628..11413)
                     /locus_tag="KR294_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBH0239726.1"
                     /translation="MSLNSIDRKKEILKLLDSKGKVNTKELVKRLEVSSETIRRYLEE
                     LENENKLKKVYGGAIKINYGVIEPEHIKRNNTNLDKKQSIAKYAAKFVNDNESIIIDE
                     GTTNLQIVDYIISVNNLKIITNSYPVLSKLISYENQGLFDGEVIFIGGKVNLKHQRTA
                     CPISIDAMKNLYVDKAFISSEGILDSFGISSIDQNKALLSKAYIKNSKESFVLCDSSK
                     IGIASMYKIADLEELDFVICDVEPPNEWKDKLNEINITWIEAK"
     gene            complement(11630..11860)
                     /gene="dltC"
                     /locus_tag="KR294_001646"
     CDS             complement(11630..11860)
                     /gene="dltC"
                     /locus_tag="KR294_001646"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HBH0239727.1"
                     /translation="MQETVIEIFEDVLGTDEIREDLDLNLFETELLDSLAIIEVLLEI
                     ENRLGIELQPTDLERKDMSTVNNLVKFLETRK"
     gene            complement(11879..13027)
                     /gene="dltB"
                     /locus_tag="KR294_001647"
     CDS             complement(11879..13027)
                     /gene="dltB"
                     /locus_tag="KR294_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HBH0239728.1"
                     /translation="MIFSQYGDYFYLYILLLTSIPAVILGLMGKNIKYYGMLASLFMI
                     FLIVGIDVQLKYLVIFIILEVIIVKGYEYVRRKTKNKYIYWGFLFASMLPIIINKISP
                     VTSFGIIGFIGISYLNFRTIQMVIEIYDGAIKEVKISKMLYFMLFFPTLSSGPIDRSR
                     RFEQDLEKQISRKEYIEEYLLPGIKNIVMGVGYKFVIAFLINTYWVSRIPKDMSFINI
                     LSYMYAYSLYLFFDFAGYSLFAIGTGYIFGIQVPINFDKPFISKDMKEFWTRWHISLS
                     RWFGDYIFSRFVMSSMRKKRFKKRTTAAHVAQMITMITMGFWHGLTWYYVAYGVYQGL
                     ALVLTDIYQRKSKFYKKHKKDKWFERVQIFITFHIVCFGLLIFSGYLA"
     gene            complement(13027..14541)
                     /locus_tag="KR294_001648"
     CDS             complement(13027..14541)
                     /locus_tag="KR294_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase"
                     /protein_id="HBH0239729.1"
                     /translation="MKIIEGIKKYSNTDRTALMCNGDKLSYKDLNEYSDAISVFLKDV
                     YKEEDTPIVIYGNKENMIMACMIGALKSGRAYVPLDISFPIDRVFEVTKEIKPKVLFN
                     FSDERNFGDINVIDMDKLNYIINEYQGKSLDKENWVKDDENAYILFTSGSTGKPKGVQ
                     ISSNNLDSFSDWISPYLNIDGSEKVIMNQPAYSFDLSVTTIYPGLIHGATLFSISKDV
                     LADYKELFRQFSISDIAVWVSTPSFAGVCITEKEFNSKMLPNLESMIFIGEALSKNLT
                     KELMSRFPNTRIINGYGPTEATVGVSVNDMTQKAIDDEKSLPVGYPMSNCKIKILDED
                     GNELKENEKGEIIIIGPSVSKGYFNNKEKTDEVFFYDEIDGVKWRAYKTGDMGYLLDG
                     NIYYCGRKDFQIKLNGFRIEIEDIENNLRKVHNVKNAVVLPVYKDEKIAYLKGIVELN
                     EKNDLSNIKNGMIIKKELGKYIPSYMIPRNISIISEFPTNINGKIDRKKLMEEI"
     gene            complement(14662..15852)
                     /gene="dltD"
                     /locus_tag="KR294_001649"
     CDS             complement(14662..15852)
                     /gene="dltD"
                     /locus_tag="KR294_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HBH0239730.1"
                     /translation="MRKLIYFITPFIIGVVFLFGLDKFLDSKTDELLREKNLLPIMDD
                     TLSDIKDKGVTANNHFLREKDIMILGSSELSNSTKQHPKYYFNTNRSKNKVFAIGRAY
                     TQTLQDAAILGSMNPNIDNKKVVLLISMQWFMEKDGVTSHHYQSRFSPIQFYRFLDNP
                     KISKQNKIEYAKKSSKLLWGSDEYKAEALYAKLYEPKTFPEKAEKVLLEPYFQGRKYC
                     IALKEKGILYKRLIKLDKKRATKRKRPINWSYERKKAIEDAKKRVGKNPLNIDKYYYK
                     EHFKDGIEQYKGRDKDVNLLTSKEFENYKLMLNVCTDLGIKPVVVLIPSMDKFYNLTG
                     ISEKERNQYYDKAQKIAESKGFEVLNLKDKGSDKYYLRDVMHLGTKGWVDVCERLFKI
                     FKEQ"
     gene            complement(16140..17159)
                     /locus_tag="KR294_001650"
     CDS             complement(16140..17159)
                     /locus_tag="KR294_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBH0239731.1"
                     /translation="MMGKIRFGIVGTSNIANIFLRAASRVKDFELVAVYSRNLEKARE
                     FGTLYGASIFFDDLEQMAKSKDIDAVYIASPNALHSKQTITCLKHKKHVLCEKSLASN
                     LKEVKSMIKTAKDNNVLLMEAMRITCVPNFKAVKENLYKIGKIRRFFGSYCQYSSRYD
                     KYKNGIIENAFKKELSNGALMDIGVYCIHPMVNLFGAPKTVKAVSHILQTGVDGEGSA
                     VFQYDDMDAIIQYSKVADSYIPSEIQGEEGSIIIEKLNLFEKAIIKYRDGREEDISIP
                     KEKAEEKPREIEGMYYELVEFISLINNNKIESNINSHENSIIVMEIMDEIRRQSSIVY
                     PADSI"
     gene            complement(17335..17874)
                     /locus_tag="KR294_001651"
     CDS             complement(17335..17874)
                     /locus_tag="KR294_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative ABC transporter permease"
                     /protein_id="HBH0239732.1"
                     /translation="MDNVGSLLYFLFNFFLYGFIGWIIENLYSYYKQGHFQEDGFLNG
                     PFKPMYAIAMSIIIEVSRFIDPNNIFALLLLCLVVPTVVEYITGILMKVYFNKVYWDY
                     SDYKYNSRGIVCLKFSVYWTILTFIGVRYFQVYIVDSLYSLIIPYWPIVVTILLVTLF
                     VDEILTIKFLRGNKDIVER"
     gene            complement(17975..18655)
                     /locus_tag="KR294_001652"
     CDS             complement(17975..18655)
                     /locus_tag="KR294_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBH0239733.1"
                     /translation="MQKVEGIIFDMDGVLFDSERISLEFWMETFEKYGYTMTKEIYTS
                     VMGRNRKGIIEGLTDIYDSSVPIIDLYDEKTKNMIEFMERKGAPIKLGVNELISFLKE
                     NGYKMAVATSTKRERAVKRLAKANLKDYFDAIVCGDDVVNSKPNPEIFLKAAKKINVN
                     PKNCIVIEDSPMGVEAAYNGGIRCINVPDLKEPDEQIKSQSHKILENLLEVREYLKSL
                     NSKECHNL"
     gene            complement(18684..19973)
                     /locus_tag="KR294_001653"
     CDS             complement(18684..19973)
                     /locus_tag="KR294_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HBH0239734.1"
                     /translation="MRELLKVTLIVMLVLINAFFVACEFAMVKLRSSRIDTMITEGNN
                     NAKRCKIIKDNLNSYLSACQLGITLCSLALGWMGESTVKELILPIVSVFNLSESIIYT
                     ISISISFLIITMMEVVIGELVPKALALYNTEKIMLSTSFLLVGFYKLTYPIIYFFNLS
                     TDLFLKPFGYSQADEVDEPHTGDEIRLLVEESYKSGLIDESEQRLVDNIFEFEEKKIR
                     EIMVPRTDMVCIYESDSEEKILAILKEEGVTRYPVCRKNKDDILGFVHIRDLYNQKIN
                     ENKIELEEILRDIIYISENLTIDKALERIRKEKLQLAIVVDEYGGTSGVVTIEDILEE
                     IVGEIQDEFDKEETHIKKIGAGSYLVDGTESINYINKYFGLDIEHDGFDSIGGWISYM
                     LGSNIKVNQSVTFENYNFTILELDKLRVVKLIIKSVI"
     gene            complement(20422..22023)
                     /locus_tag="KR294_001654"
     CDS             complement(20422..22023)
                     /locus_tag="KR294_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HBH0239735.1"
                     /translation="MIYDLILKNGFIIGGTGNPGFYGDIAIKDNLIAKIDSKINSNTN
                     KEIDCCGKVITPGFIDPHVHEEIVAILDGKFEKFLKQGVTTTINGNCGHSITPYSSEN
                     VYEYMYKNGLLLEEEKKYLIDKNKCWNNFTEYCDLISKSGISVNMGFLLGHGTIRWSV
                     MGGSKDRPPTEKEKNEITDIINDGMKSGAFGISTGLAYIPSKYADIDELVDIAKQIKE
                     HDGIYTSHIRDYIGRYNAVKEAIEVGQKSGARVQVSHLSPVEIEAFDEILKARYNGVE
                     IMVDTVPRSSGHCMKKKRVIQFIMAISSSLFELGINGVMDALRNEEGRTLILKEAFIL
                     GDRGSIILLNTKDINMEKKSIREIATQKGIDEDKLLLDLLLDGDEELIFCLGGMYRAD
                     FPDKLHDDKIIDNPFVMVGSDCLFSVGGDMSWFELQRRGAFPIFFNMYRKSGVRLEEI
                     VRRVTSLPARQFKIKNRGILKEGLIADIAVIDMDNYSYSRSEDIDFSKPQLLANGVEY
                     VIVNGKIALENGEITENKCGEVLKR"
     gene            complement(22134..22811)
                     /locus_tag="KR294_001655"
     CDS             complement(22134..22811)
                     /locus_tag="KR294_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239736.1"
                     /translation="MSKVKSIYNEEYLPFKIRYGRLTLSLGIIAALVPGIILSFGFGI
                     MPPISALLASTMAIVSMSAPNYIIEPVSYSPILGIPGTYMSFLSGNISNMRLPCSIAA
                     QKAAEVESGTEEGSIISTIGIAVSILVNISILTIGVILGGSVLSKIPAEVVEKLNLIL
                     PALFGSVFGQVFLQDKKLGLVAIVISVLTIILSKQGIIPQSLVVLICVFGTMLIARAM
                     YKDKLSD"
     gene            complement(22824..23519)
                     /locus_tag="KR294_001656"
     CDS             complement(22824..23519)
                     /locus_tag="KR294_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5058 family protein"
                     /protein_id="HBH0239737.1"
                     /translation="MDYLKLANHPLLWIASTVAVSIVVVQSLIFAIKSCKVGKTMGIT
                     DKQIKSAVKSSAISAIGPSMTIFAGMVSLIVTMGGPIAWMRLSFIGSVIFESMSAGFG
                     TDALGITLGSPEMTKLAFTNAVWTMILGSLGWIIFTLLFGHKLDKITNVISSGKKSFI
                     PIISLGAMLGSFAYLNADRVLRFDNGTIACISGMAIMVILCMLEKKKNIKWLREWGLT
                     ISMFSGMIIASVI"
     gene            complement(23571..24770)
                     /locus_tag="KR294_001657"
     CDS             complement(23571..24770)
                     /locus_tag="KR294_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HBH0239738.1"
                     /translation="MKSAYKGYEAYSYLEKGKDISSIEMCKGDKRVKEYLIELDDIQE
                     AKVKSIVDEKIFISLHEHPVLFPEHLERDIFEYNREGKQRCAYEALSRGYYDAIFDNL
                     MDGVCTITSNSGWKWDDILIDLGMRLCDLAHQDFVIKCEKVEDIYRAKSEGKVALIPT
                     LEGAAPIENELDRIDILYGFGIRLMGITYSESNALGSGLKEEKDGGLTNFGKKAVERM
                     NKIGMAIDCSHVGVQTTLDVIEYSKDPIILSHVGARSLWNTKRLTPDEVLIACAKKGG
                     VIGVEAAPHTTITEKNKEHSIESFMEHFEYIKNLVGIDHVAFGPDTVYGDHVKLHSVL
                     AAKFDIKKITGTKEHPKVEYVKGLENPTETSKNIVRYLVKHGYSDEEIEKVLGGNILR
                     VLKQVWK"
     gene            complement(25031..27076)
                     /locus_tag="KR294_001658"
     CDS             complement(25031..27076)
                     /locus_tag="KR294_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH0239739.1"
                     /translation="MKKHNILFVSTDDKINIDISKQLENIFGEFCNIDNLVYVNRINI
                     ELSSYELVVCSDNDIKEYIHNNIDKNIPIVIVHRTINIENINQIISIENDSDVMVIDA
                     YKESADETAKIIRKLGLIHINLIPYYPGCDKSKCEIGIITGSRNSIPQNIKQIIDIGD
                     KVIDINTVIEIFTKLNISIDKLHIIKEKYNEDTVSGYRYYTTMNKTMKSFLEIIDEGI
                     ASVDKLGKFIYCNKVFSNLVGIDQNEIISNNFMDLFSDKVVKKIFFQEDEVNDEVVNL
                     NNKKLIINKVNVYENNERIKSIISIKNISAIQVLEDKIQNKLQSKGFVSKYTFESVVG
                     ESKIIKEKINIARKIATTDFSVLILGENGTGKEIFAQAIHNESLRKNKPFVAVNLSSL
                     SDTLIESELFGYDEGSFTGAIKGGKMGIFERAHTGTIFLDEIGDISLDVQQRLLRVLQ
                     EKEVMRMGGSKIIPIDVRIIAATNKDLKKKIKEGSFREDLYYRINVLHIEIPRLRERK
                     EDIPLISKYFLDEINSNKCFTEESMQALTLYEWPGNVRELKNLIYYIDTIVEEDRVDY
                     EHLPEQFRFEKNNTLVNENFDSIILDFKQSNFFEESICILTSIETWNNKNILLGRNKL
                     QEILKEKDIVLSVDQIRKRIDKLKSHGLLLSGVKKQGSFITDEGKNFISYVKIKGVI"
     gene            complement(27487..28296)
                     /locus_tag="KR294_001659"
     CDS             complement(27487..28296)
                     /locus_tag="KR294_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBH0239740.1"
                     /translation="MYYVYVNDINIAVYDLNPSAKKTVLFIHGWPLGHKIFEYQTNIL
                     PKLGYRTVSIDLRGFGKSDATSGGYTYSQLADDIYKVVHAIGLKDFTLVGFSMGGAIV
                     LRYMSLFNGYGVSKLVLAAAAAPSFVQRPPEFPYGMTREDVNKLIAQACTDRPEMVTD
                     FGEKVFASNPPESFRRWFNDIGFSASGIGTIGTAVSLRDEELFNDLKCVRVPTGIFHG
                     KLDEICPYEFAVFMNEKIEDSILYTFEYSGHAIFYDELKLFNQKFLQFLEE"
     gene            complement(28380..28913)
                     /locus_tag="KR294_001660"
     CDS             complement(28380..28913)
                     /locus_tag="KR294_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HBH0239741.1"
                     /translation="MSDAHYDMHKRNGYSSDEPYPEIKVLGPNKYYAELLMDDYAGVS
                     SEFTSVNQYLYHNFDLDETHRELSEMWINISITEMLHMEILAKTIRLLGGNPVYRGST
                     SSCGAYWNGGFVCYGNSICNRLKLDLHLEHVAINNYYKDISLIEDPYIKAILNRIILD
                     EKLHVSLFEKAIEKYCK"
     gene            complement(29063..30412)
                     /locus_tag="KR294_001661"
     CDS             complement(29063..30412)
                     /locus_tag="KR294_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TldD/PmbA family protein"
                     /protein_id="HBH0239742.1"
                     /translation="MELKNFKDILFKKALSEGFEEYEIYYYTGENLSINIYEGEVEKY
                     NLDKSFGLSFRGKVNGKIGYSYTEILDDKAVDMLIKNVKDGVNTIENEDVQFIYEGDK
                     HYNDVKTYSKELENLEADKLIDLALEMERETKAYSDKVVNLSKCTISYSVSSNGISNT
                     KGLNLSNKTNMLIGFVVPIIEDNGQKYDGIGYNIANSIEEIKPCEIAKLGVDNALSKV
                     GGKSIPSGKYKTILLNEAMVSLLSTFSGIFNADSAQKGLSLLKNREGDMIASPIVTIV
                     DDPLLENGMASTPFDDEGVATFKKEVVLNGKLITLLHNLKTANKAGVKTTGNGIKSSY
                     SSPISIYPTNFYIEKGDKSLDEIIKDIDEGLMVTSFAGLHSGANSVTGDFSLAAKGFY
                     IKEGKKVFPVEQITVAGNYFDLLKDIEAIGEDLEFPMSSIGSPSVVIKELSVAGKDE"
     gene            complement(30424..31806)
                     /locus_tag="KR294_001662"
     CDS             complement(30424..31806)
                     /locus_tag="KR294_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011967718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TldD/PmbA family protein"
                     /protein_id="HBH0239743.1"
                     /translation="MLSKNIASKVLEKCLITGGDFAEIFEEDTINNSISLIDNKVENA
                     IGGRNYGIGIRIFKGLKSIYAYTSDNSLNSLLDVAYKAAVALGKLEDGKSVILNDSIK
                     INNIHNIKIYPNSIGNKDKVSVMKVAYKSAKEFSNDISQVSVSYLDKDQKILIANTEG
                     IYVEDRRIRTRLGISSIASKGNENQTGFEGPGGCKGFEIFEEIDPEYYAKESARVAHT
                     MLHAKNCPAGNMMVAIDNGFGGVIFHEACGHSLEATSVAKGNSVFADKLGQQIASTKI
                     TAIDDGTIPNYWGSMNIDDEGNPTQKNILIENGILKSYMIDKLNGRRMGMNPTGSSRR
                     QNYKFAPTSRMTNTYIAAGEDRPEDIIKSIPDGLYAKKMGGGSVNPVTGEFNFAVSEG
                     YLIKNGEIQEPVRGASLIGKGSDILMNIDMVGNNVKQAQGMCGSSSGSIPTNVGQPMI
                     RVKEITVGGR"
     gene            32050..33264
                     /locus_tag="KR294_001663"
     CDS             32050..33264
                     /locus_tag="KR294_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HBH0239744.1"
                     /translation="MNQEYVKGNPIFTNINKVPRQFPYLTDDIDTDVIIVGGGVTGCI
                     CAYYLAKNNIKSVILEKGRIAHGSTSVTTSLLQYELDDNLIDLTEVMTLKDALKAYNL
                     CTSALEELDTFIELYGNKCDYAKRDTLLYTANKLEVKAIKEEYNLRKENGFDVEYIDE
                     STNPFNFDLKSGLIAKNGGRELDPYKYSHHLIDVSLKNGLQVYENTEVKKVDLSNDKV
                     TAEVSYGYKVHGKKLIVATGYNTSLFTKRNFATKSNTFNIATKPLKNIASWKNNILIR
                     DNCDPYNYLRTTKDNRLIIGGEDVSFDDIENETLANEKYDILEQRLKSMFKDIKDIEV
                     EYKYCGCFASTLDNLGFIGPDNKNNNLWYCLGYGANGILFAILGGIMLSELYLGKQNK
                     NMKLFKVDRFDK"
     gene            33441..>35231
                     /locus_tag="KR294_001664"
     CDS             33441..>35231
                     /locus_tag="KR294_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH0239745.1"
                     /translation="MKYGGIIMKEILVIAPTKGTYEKSIHIVKKNKYTNIDVVFGNLK
                     EGIPLAEKSINHGTRIIISRGGTYNMLKATYNIPIVEIKVDAYDIIKSYKEVKNSNEP
                     FGIIGFNNVIYGFDIIEEILNKKITMIEIEKEEEIYDAIEKYRKKGINTYIGDTTVAH
                     IVKRLNCKGILIESREENILRAIQQAEQILEATKDEQKRRLQIEAMTDFVHDGIITVD
                     KNFKITLFNKSAEKIFGIKKENALYHNVVDVIPNTVLPQVVETMEPQIGEIQNIGSTK
                     IITNRVPIIVDGQIQGAVSTFQDSKEISSFEHTIRRSLLSKGLSAKYTFDDIIHASEK
                     TKDCIELAKKYACYDTPMIITGESGVGKELFCQSIHNYSKRKNAPFVAVNCAAIPPSL
                     IESEFFGYEEGSFTGARKKGKAGVFELAHEGTIFLDEISEIPLELQGRLLRVLQEKQV
                     MRIGGDKVIPIDVKIICASNKDLKNMMRNGLFRQDLYFRINILTLYLPSLKERKEDII
                     KLSEFFIHKYSSKYNKTPLIITPNIKKALLEREYEGNIRELEGMMERAVIVESFDSIL
                     LEKVSNEYTNNIVDKDNSDFECSNLDLKTLE"
BASE COUNT        11725 a         6080 c         3790 g        13636 t
ORIGIN      
        1 aagtcttact gcaaagtaat atacatagtt ttttaataaa ctaataagtg caattaataa
       61 ctacttaatt gtttaatata gtacatagat aactttaata aatctacagt tatttaaaaa
      121 ggtagaatca ataaaattat acttataaat cttcaataca ataattaaaa tttaataaaa
      181 atataattgt tgatttaact gtaatcttat ttaattctac ctaacttatt atataaaact
      241 attttttata gattataaaa tatctaactt tcatctactt caaagaatac aatacttctc
      301 cttctcttat agtctgcaat actttaatat cttttatttt catagggtcg attgtaagtg
      361 ggttttcatc taatattatc aaattagcta atttcccttc tttaattgaa ccttttttat
      421 cttcttcaaa atattgatat gctgcattta tagtaacacc ctttaaagca tctaatgggc
      481 ttatcttttc attttctcct atttgtatac ctttttttgt aattctattg acagcacacc
      541 atactgtttc cagcatatta ggtgctatta ctggtgtatc ctgatgaaga gtgtaaatta
      601 atcccttttc tatagttgtt ttaagtgggc taatcttaaa cgctctatct tctccaaggt
      661 ttttgatatg aatatcaccc caataatatg tgtgagctac aaaatatgaa ggtatcatat
      721 ttattacttt catatcatca atctggtctg ctcttactgt ttgagcatgt atcataactg
      781 gtcttatatt attttcacta ctttgctctt ttaagtttaa aactttctca aacgcatcta
      841 tcaactggtc tgctgctgca tctccattac aatgagttaa gagttgcatc ttttctttta
      901 gtgaaatatc tataaacttt tctacttctt catctttgta tataggatat ccacaataac
      961 catcatctga attttcatat ggtctactca accatgctgt cttaccttgt ggagaaccat
     1021 ctaagaaaat cttataacct cctattttaa atctatttat atattttttt ataaactccc
     1081 tattattatc tgctacagac ttactttttt tcaaatttac atatcctaca acatccattt
     1141 ttaatttatt ttgatttgcc attgctttta aaatgttaaa ttgattttct tccattaaac
     1201 cttcttgagc tgttgtaata ccatagctta gatatatgtt ctgtgctttt tcaattgaat
     1261 taaaaatctc atttgatgat ggttgtttta ttttagatgc tacattaaaa aatgcatttt
     1321 cttctaaata tccatttggt tcttcactgc cttctactct acctatatgt ccaccttctg
     1381 ggtcacgtgt ttcattggta acaccaagct gttttaaccc caatgtattt gcaactccca
     1441 tatgaccaga agcatgtgaa attagtattg gattttctga agatgcacta tcgagtacac
     1501 tcttatctgg atgcttattt tcttctaaaa aattattatc atatgaaaat ccaattatcc
     1561 agtctccttt ttttatatta ttcgactctt tgaaatcctg tatttttttt actatgtctt
     1621 taaaactggt tgcatcttct aaaggaacta gctttagagt agtagcaaaa gctatcaagt
     1681 gactatgtga atctataaaa gatggcatca atgtcttacc ttgtaaatct ataatttctg
     1741 tatctttatt tttcaaagca aatacttctt cttttgttcc tatctttttt attattttgt
     1801 cttttataag aatagcatct ccacatattg aatcttccat tgtgatgata tttccattgt
     1861 aataaatttt tgctttcata aaattctcct tacgttgtct actttaataa atttttttca
     1921 ttattttctg cttaattata ttatcttctt tataaacttt ttctttagag tttaatcata
     1981 taaaagtttt atttttaatt attgtttgcc aagaagtaaa tactattcat tgtaaataag
     2041 acaaattaat aggctttata ctaattgaaa aaatattata agttgttaaa tttaaatatc
     2101 taaactcaat tatatctgta caattgtaat tttttaaatc atgatgtatt attttaaata
     2161 tacagttaca ttattattca caatataagt atcttagttc tcaaataaca tctcatgtaa
     2221 tctattcaat gcaaaaaatt taaatatttt ttaggaggtt ttttatgagc aaggaaaata
     2281 aaaatgtaag aattgctgtt gtccaggcgt caccagtcat aatggattta gaaaaaactg
     2341 ttgaaaaagc attaggatta attaaagaag ctggtagaaa aggggcaaat atcgtagttt
     2401 tccctgaagc attcatacct gcatatccaa gaggtctttc atttggattt gttgttggaa
     2461 gtagaacaat ggaaggtaga gaagattgga aaagatacta tgataattct gtaccagttc
     2521 ctagtgctac aacagattta ttaggaaaag cagcacaaga agcaggagta tatctatcaa
     2581 tgggtataac agaaagagat ggtaatgata taaattgtac cctttattgc acaaacttat
     2641 ttttctctcc agaaggtaag ctaattggta aacacagaaa acttaaacct acaggaacag
     2701 aaagatgtat ttggggagaa ggagatggaa gtactcttac agtagttgat actccatatg
     2761 gaaaaatggg ttcgttgatt tgttgggaaa attatatgcc attagctaga acagctcttt
     2821 atgctaaggg tgtaaaactt tacatagccc ctactgcaga ttcaagagaa gagtggcaag
     2881 caactatgaa acatattgct ttagaaggaa gatgttttgt aattggatgc aatcaatatg
     2941 ttgaaaaaaa tacgtaccca actgacctta actactataa ggagctagat gcagaaccag
     3001 aaattatgtg tccaggagga agttgtatag ttgacccttt tggaaaatat gtagcaggtc
     3061 ctattttcaa taaagaagaa atgctaatag ctgatttaga cctagaaaaa atagtactta
     3121 gtagactaga ttttgattca gaaggtcact attcaagacc agatgtattt gaattaattg
     3181 ttcatgaata atctttttac acaaacatct acataaatct ttttacataa aaaaatgaga
     3241 tactcataag taaatttcaa gtatctcatt tttgcttaaa acctataatc ctaattataa
     3301 atttattcac ctatattttt tctaaatcaa ctactgttct tccaacatgt tttcctgcca
     3361 ttattgaatc tatactatca tttaactctt ccaatgatac tacatttacc atatcatcta
     3421 aatcatctaa tttccattca tttgataata aatcccatat ttttaatctt aagttcattg
     3481 ggcaatccac agaatctata ccatataaag taattccctt taagataaat ggatatactg
     3541 aacttgtaaa atcaactcct cctgcattac cacaagttgt tactgctcca caataattag
     3601 ttgtctttat tgctgttgct agagtatttc ctcctactgt atctattact ccagcccatc
     3661 ttggtctaag cagaggtctt cctgagttat catccacttc tgacctatgt ataacatctt
     3721 taacacctaa gtttagtaat acttcttttt gttcttctaa ttttcctgtt gaaactacaa
     3781 ctgaataacc taatttaatc aatattttag ttgcaattac agcaactcct ccagtaccac
     3841 cagtgactaa tacatctccc atattcttgt ctacagaatc tataaattta tacacagata
     3901 aagctgctgt aaaccctgct gtaccataat ccattgcttc ttttagtgaa agatttttag
     3961 gaagtttaac tacccaacta gaaggaactc ttatgtattc tgaaaaacca ccagaagtat
     4021 tcattcccaa gtcataacct gttactaaaa cttcttctcc aattttaaaa tcatcacaac
     4081 tactagattc tactatacca gatgcatcaa ttcctggtgt atgaggatac tttctcgtaa
     4141 cacccttatt accatttgca gaaagtgcat ccttgtaatt taaagaagaa tattttactt
     4201 ttattaaaac ttcgccttct ggcaatgtat ccacttctct ttcaactata tttcttctaa
     4261 aatttccttc ttcttctgta atatatagtg atttaaattt tttattcata aatttcctcc
     4321 caatacattt agttttatgt taaactaatt atagtttata aatagtttta tgtcaaacta
     4381 atttaaatag attaaagatt ggagaataat ttatggaaga taaatatatt gtacatttca
     4441 taagtaaaac aaaggctagt atgattaaat tcattgaaaa taaactcagt aaaaatggtt
     4501 taggtgagtt aatacctact catggaaata ttttaactgc actttatgaa aataatggaa
     4561 tacttacaat gaaagaaatt gcagctaaaa taggaaaaga taaatccact gttacagtgt
     4621 tggttaataa acttataaac ctaggatatt tagaaagaca aaaatgtaca aatgacaaac
     4681 gtatcacgta tataaagctt acaaaaaagg cactgcttat agaagatact tttaatagca
     4741 tctcaacaca agttaaagag acggcatatc ataatattac agaaaatgag aaacaagaat
     4801 ttcttagaat tttaaaaaaa attaatgata attttaaaaa tgctgactaa attgagcata
     4861 attatatctc ctattggaat aataaataaa aagaatcaaa tattgtaaaa atttattgtg
     4921 atagagaggt agaatatgaa tttaaaagat agtaaaacta aagaaaattt attaagagct
     4981 tttgcaggtg agagtcaagc tagaaataga tacaatattt ctgcatctgt agcaaaaaaa
     5041 gaaggattat atataataga gtctttattt aattacactg ctgaccaaga aaaatcacat
     5101 gcaaaacaat tcttttctaa attaaaagaa tttgctggtg aaaatataag tatatcagga
     5161 gcataccctg tagatttata tgacaagaca gcacaacacc ttaaagctgc acaacataat
     5221 gagcttcaag agtgggatga tgtatataaa aactttggaa aaacagcacg tgaagaagga
     5281 tttgaatcta tagctaagtt atttgaaaat atagctgaaa tagaaaaagt tcatggtgat
     5341 agatttggta gatatgctac tgatttagaa gaaggtactt tattcagaag aaatgaagat
     5401 atacaatgga tatgtacaca ttgtggccat atacatatag gtaaagaagc tccaaaagct
     5461 tgtcctgtat gtcttcatcc acaaggatat ttcttagatt ttaaaaactc attatttgaa
     5521 taaattaagg caataattct atttaaacaa tttactatat ttatatcaag tatttttata
     5581 aatactgtat tatcttaata acaataaaat gaaccattga tattactata agtagaaaat
     5641 gtagtttaaa tacaatttat agtaattcat catggttcat tttattgttt actaatccct
     5701 ataacctact taaatctatc tttaactttt acatactcac ataaaatctt atctttaaac
     5761 taaatattta aataaagtgt attttaagta tattattata atacattata taagataata
     5821 cactatgata actttatact tatatcattt atttcttttg tcaagtcaat ctcaataatc
     5881 ttaactacat ctttttcaaa ctttactttt ttataatcca gacatcctac tacgaatgga
     5941 actccaaact ttctaaacaa ataaatcttt ccactttcat tgtatattga tgtaaaattt
     6001 tcttctatta tattcactat caattttaac tcttcaaaag ttattataga tttaactaaa
     6061 aacttctcta ttatgctcaa tataagcagt tcttttttac ctatgctttg ctctttttta
     6121 tataaatttt gaaatatttc tttggtataa ttacatataa cttctttact gagaataaaa
     6181 tcaatgtcaa attctttatt aatatccttt ttcataaaca tatttgcaat atcatcaaga
     6241 gaagtctctt ctttcataga caatattaac tctattcttt ctagtatttt atctcttgga
     6301 aagaaagtct cttgacctgt aaaagctgat ttttttataa accattcctc tggtattatg
     6361 ttttttcttt tccatctata taattgacca taagatatat tagttttgct caataaatct
     6421 ttcttagata ttaattcttc cataactttt ctagcccacc tttatactgt tttttacagt
     6481 agaattatct gaaactgata aattatcact gtattcaata tttccaacat cacaattatc
     6541 tactagagat atgcttttac ctcgtatatc ttttattgat gcatcttcta attcaatagt
     6601 atctccctct atcaaattac atttaaactt tcctgaaaaa atattaatga ttttaattaa
     6661 tgaaaaagca tctttgcttc ttcctatttt tatattagtt gcccctatct ctttacaata
     6721 agaacctcct cctgaataaa catatatatt ttctccattt aaaagaccat cacattttat
     6781 tgctccatat acctttatat cttcacattc tatatttgat ttatttctca tttcgccata
     6841 gatttttata tcttgtgcat acatattttc atttacactt aattgtcctc ttattgtaac
     6901 attattacat ttaagtttgc catccacttt ctgttgagca gttataacta agtcatctat
     6961 ttctgcatct ccctctatat taagttgacc attcactctt acacgctctg ctttaagatt
     7021 gcctcttata atagtttttc cgttaacaac aaaatttttt atattgatgt caccttcaaa
     7081 ttttgcatct ccaagaactt ttacttcgtt acttttaaca tttccttttg atttagagct
     7141 tcccacgatt tttatatttt catactcacc actacttata aagccttctc caagtatttt
     7201 tatagaccct ttttccatat tattacctca ttttaaattt tatttttaaa cctacttatt
     7261 acttatcctt ctttaatttt attttttcac ttatattctt tatttcacca actattgaat
     7321 cttcatcaat ctctatactt tcactgtact ccaaactttc tacataacat cccttgccta
     7381 ttttaatatt ttttcctctt acaactttga cttcactatt ttctaagctt atttcatctg
     7441 cttctataat atttgcaaac aatttacttt ctgtatactt tctaattgat aatagaccta
     7501 aacttatcaa atttgaagac actttttcaa agttgatatg ctttttttct agcatacgaa
     7561 attttttgca ataatctcca tgcccctttt ttatatttat actacttgct ccaacttcat
     7621 taaaattaga agttccattt aaactaatat taacttcttc acaattcaaa aatccattac
     7681 actccaagat tccacttaaa ttgatatttt cacaatctat attctcattt gcttttaaat
     7741 atccttctcc atgaataata tcagatttta tacttccttc tacattaata attccactag
     7801 tatcaatttc aacagaatta atatttcctg tacatctaag aagtcccgat atctcaactt
     7861 ttgatgccag tatgtttcct tctactttac ttaaaccaga tgtaaaaaat tcattacatt
     7921 ctgttgtccc aaaaactttt gctgaaccag aagaatcaaa tttactacat tttacacttc
     7981 cttctatttt gcctgttcct gatatattaa cattatcaaa aattccacct ttacattttc
     8041 caacaccatc aaatcttagt gaacttaatt cttcattcat aatgatatcc tttctttacc
     8101 gtattttatc tttaaaccta atataacaaa acattgttac gttgtcaagt atgataataa
     8161 tacttaataa agcaactatc atttattttc tataaatagg cataaaaata atagggaaat
     8221 gctttattta aactataaat ctaatttctt agattgtggt ttaaataaaa tatatcccta
     8281 ttactcaatc tttatatatt cattgtataa acttctaaaa tataagtctt taaattctac
     8341 tgtcaatact ttttatacac tgtttgtgct atcatctcac acacctaaag gagtgggctt
     8401 tccacactat tctgtaacct acaagacact atcttcttct atctattgat aaatttttct
     8461 attacatcag ctagtctctc catatcagtt ggataaactt cacctatgct acctattcta
     8521 aatgtatcta tatcagtcaa tttacctgga tagataacaa atccattatc ttttaaataa
     8581 gtataaaatt ccataaattc aaactttgca tttttaggat ataagaaagt tgttattaca
     8641 ggtgattgag cattatcatt caccaaagta tcaaatccta aagattttaa tcttgaagct
     8701 attgtaaact gattttcttt atatctagca tatctttttt caacagaacc ttcttcttcc
     8761 aattctaata aagcttgata aaaagctctt acaacatgtg taggtgaggt aaatctccat
     8821 ttaccattat ttttctccat agtctcccat tgcgcataca catcaagaga taatgattta
     8881 gctatacctt tacatttaga taatttctct ttattagcta ttataaaacc aaatccaggt
     8941 actccttgta tacatttgtt agaactacta actaaaaaat ctatattaaa atcttcaaca
     9001 tcaatctcaa ttcccccaaa actactcata gcatcaacta tataaatttt gttatattct
     9061 tttgcaagtt tccctacctc ttgtatagga tttaatctac ctgtagtagt ttcacagtga
     9121 accattgata tatgtgttat atccttgttt tcttttaata aattttctac tacatttaaa
     9181 tccactgctt ctatatcttt aaaagtgcag tcaacaaatt gtatgttaag ataattacat
     9241 atatctttca ttctctttcc gtatgctcca tttgcaatta caagaagttt accatctttt
     9301 gaaatagtac ttcctattat agcttctact gaaaaagtcc cacttccttg cattaataca
     9361 cttgtgtatt tatctgtatt ttgggttgct agagatacta atcttcttct aacatcttgt
     9421 actaggttat tatattcaac atcccaagta caccaatctt ttaacataga tgctcttact
     9481 gatttagtag tagatagtgg tcctggtgta agtaatatgt aatcattttc tggtacaaaa
     9541 tctgatttaa tagtttcatt ctctattttt attagtatat cttctaactc agccatagtt
     9601 tctattacaa aatgtgctcc tgcctcttta aatttctttg aaactatact catcttagct
     9661 tttaattctt ccttatccat gttctctact tcttcttgtg taagccctaa ctcacttgaa
     9721 ccttttatta cagcaacact ccacattcct gcatttacgc cttcttttac atcacttatt
     9781 gtatctccta cttttaccat agaactcata ggagacaccc ctaaagcttc agcattttta
     9841 tagcacatcc aaggatatgg tcttccttga gatacttctg atggtgttac aagaaaatcg
     9901 ggtgagtatc ctttctttgc tgcatttggt tcaactatgt tcatcatctc tcttgtataa
     9961 cccgttgtag aacctatttt taatccattt tttctcaact tttcaatagt ttcaacaaca
    10021 tgaggaattg gagtcgtata ctcttctaat gtctcaaata acattggctc aaattcagca
    10081 taaagttcat ttacatcatc ttcagttggc actttaccaa acttatctga ccaaatattc
    10141 tttattctat ccatttcaca catttctctt atatggtcta tttttaattt tcccataggt
    10201 tttcttgctt cttccattgt tacatctata cctcttcttt taaatatctc tataaataca
    10261 ttaagaggtg caaaacatcc ataatctact gttgttccag cccaatcgaa tactactgct
    10321 tttatttttt ctccatatat ctttttcata tttatagcct ccatagattc tttttagaat
    10381 ttttgtgttt ttaattgttt ttacttttaa agtataactt tcatatgtta attatacatc
    10441 atatttaggt taaatatata ttaaatttct gtttttagtt gtatttagtt gtttttattt
    10501 tgtatcatat tcccataaaa tcctaagtta caatctaaaa tttactttct aatcttaatc
    10561 tatgaactga ctatatttta tgaatttagt tgtattgagc atagttgtat tatataaaac
    10621 taagggttta ttttgcttct atccatgtta tatttatctc atttaactta tccttccatt
    10681 cattcggagg ttctacatca caaataacaa aatctaattc ctctaaatct gctatcttat
    10741 acatactagc aattcctatt ttagaactat cacataatac aaaactttcc tttgaatttt
    10801 ttatatatgc ttttgacaac aatgccttat tttggtctat actactaatt ccaaaactat
    10861 caagtatacc ttcactagat ataaaagctt tatctacgta taagtttttc atagcatcta
    10921 ttgatattgg acatgctgtc ctttggtgtt ttaaatttac ttttccacca ataaatataa
    10981 cttctccatc aaacaaacct tgattctcgt aagaaatcaa ttttgacaga actggataag
    11041 agtttgtaat aatttttaaa ttgtttacag atattatata atctacaatc tgcaaattgg
    11101 tagtaccttc atctatgata attgactcat tgtcatttac aaacttagct gcatatttag
    11161 caatactttg ctttttatct aggttagtat tgtttctctt tatatgttct ggttcaatca
    11221 ctccataatt tatttttata gcaccaccat ataccttttt taatttattt tcattttcta
    11281 attcttccaa atatcttctt attgtttctg atgatacttc taatcttttt actaattctt
    11341 tagtgtttac cttccctttt gaatctagta atttaagtat ttcttttttt ctatctatcg
    11401 aatttaaaga cattcatttt cctcctaaat ataatatatt tttctcctat aatattacaa
    11461 tgatacctaa gatttatgaa atcatattta tgtattaaat tttttactta attaaagtta
    11521 ttttcaaaag actttgtatt atcattaaaa aagtccatca aatattagta tcagatggac
    11581 tttgtaaaat tttattttat aaattaatat ttaaagtcta actactaatt tattttcttg
    11641 tctccaagaa ttttactaaa ttatttacag tagacatatc ttttctctct aaatcagttg
    11701 gttgaagctc tatccctaat ctattttcaa tttcaagtaa aacttcaatt atagctaatg
    11761 agtctaaaag ttccgtctca aataaattaa ggtctaaatc ttctcttatc tcatcagtcc
    11821 ctaatacatc ttcaaatatt tctataactg tttcttgcat aaattttcct ccttaaaatt
    11881 aagctaaata acctgagaat atcagcaatc caaaacacac aatatggaat gtaatgaaaa
    11941 tctgcactct ctcgaaccat ttatcttttt tatgtttttt ataaaattta gattttcgct
    12001 gatatatatc agttaacaca agtgccaatc cttggtatac accataagca acataatacc
    12061 aagttagacc atgccaaaat cccattgtta tcatggttat catctgagcc acatgagcag
    12121 cagtagtcct tttcttaaat cttttctttc tcattgatga cataacaaat ctagaaaaaa
    12181 tataatctcc aaaccatctt gaaagactta tatgccatct tgtccagaac tctttcatat
    12241 ctttgctgat aaatggcttg tcaaagttta taggtacttg tattccaaat atgtaccctg
    12301 tacctatagc aaataaacta tatcctgcaa aatcaaagaa caggtataaa ctatatgcgt
    12361 acatataact taaaatattt ataaaactca tatctttagg tattcttgat acccaatatg
    12421 tatttatcaa aaatgctata acaaacttat aacctactcc catgacaata ttttttattc
    12481 ctggcagtaa gtattcttct atatactctt ttctagagat ttgtttttcc aagtcctgtt
    12541 caaatcttct tgacctatca ataggtccag aacttaaagt tggaaaaaat aacataaaat
    12601 aaagcatctt tgaaatttta acttctttta tagctccatc ataaatttca ataaccattt
    12661 gtatagttct gaaatttaag tatgatattc caataaatcc aattattcca aaagaagtaa
    12721 ctggagatat tttatttatt attattggga gcattgatgc aaacaagaat ccccaatata
    12781 tgtatttatt tttagttttt cttcttacat attcatatcc tttaactatt attacttcaa
    12841 gaataataaa tattaccaag tactttagtt ggacatcaat tcctactatt aagaatatca
    12901 taaacaaact tgccaacata ccataatact ttatattctt gcccattaga cctaaaatta
    12961 ctgctggtat tgatgttaat aataatatat aaagataaaa ataatctcca tattgtgaaa
    13021 aaatcattaa atttcctcca taagtttctt tctgtctatt ttaccattga tatttgttgg
    13081 aaactcagag attattgaaa tatttcttgg aatcatatat gaaggtatat actttccaag
    13141 ttcctttttt attatcatcc catttttaat attacttaaa tcattctttt catttaactc
    13201 aacaatacct tttaagtaag caattttttc gtccttatat actggtaaaa ctactgcatt
    13261 ttttacatta tgtacttttc tcaaattatt ttctatatct tctatttcaa ttctaaatcc
    13321 atttaattta atctgaaaat cttttcttcc acaataatat atatttccat ctaaaagata
    13381 tcccatatct ccagttttat aagctctcca ctttacacca tctatttcat catagaaaaa
    13441 tacttcatca gtcttttctt tattattgaa gtaaccttta gaaactgatg gtccaattat
    13501 tataatttca cccttttcat tttctttaag ctcatttcca tcttcatcaa gtatttttat
    13561 tttacaattt gacatagggt atccaactgg aagacttttt tcatcatcta tagccttttg
    13621 agtcatatca tttacactta caccaacagt agcctcggtt ggtccatatc cattgataat
    13681 tcttgtgttt ggaaatctac tcataagttc tttagtaaga ttttttgaaa gtgcttctcc
    13741 tatgaatatc attgactcaa ggttaggaag cattttacta ttaaactctt tttcagttat
    13801 acatactcct gcaaaagaag gagttgacac ccatacagct atatctgaga tactaaattg
    13861 tctaaatagt tctttatagt ctgctaatac atcttttgat attgaaaata atgtagctcc
    13921 atggataaga ccagggtata ttgttgtaac tgaaaggtca aaagaatatg ctggttggtt
    13981 cattattact ttttcacttc catctatgtt tagatatggg cttatccaat ctgaaaagct
    14041 atctaaattg tttgaactta tttgaacccc ttttggcttt cctgtacttc ctgaagtaaa
    14101 tagtatatat gcattttcat catcttttac ccagttttct ttatctaatg attttccctg
    14161 atattcattt attatataat ttaatttatc catatcaatt acattgatat ctccaaaatt
    14221 tctttcatca ctaaagttaa ataatacctt tggttttatc tctttagtga cttcaaaaac
    14281 tctatcaatt ggaaaactaa tatcaagagg cacatacgct ctacctgatt ttaaagctcc
    14341 tatcatacat gccattatca tgttttcttt atttccataa attactatag gagtatcttc
    14401 ttctttgtat acatccttta gaaatactga tatagcatct gaatattcat ttaaatcttt
    14461 ataagaaagt ttatctccat tacacattag tgctgttcta tctgtatttg aatatttttt
    14521 tattccttca ataattttca tataagaatg ctcctttaaa atccgttata aataaatggc
    14581 aattctttaa atggagtaaa tgttagaact cctatcgcca atattataac catagttaaa
    14641 caaatactag ttaacaaatc tttattgttc tttaaatatt ttaaataatc tctcacagac
    14701 atctacccat cctttcgtac caagatgcat tacatccctt aaataatact tatctgaccc
    14761 tttatcttta aggtttagaa cttcaaagcc tttgctttct gctatttttt gtgctttatc
    14821 gtagtactga tttctttctt tttcagaaat accagtcaaa ttatagaatt tatccatact
    14881 tgggattaat acaacaactg gcttaatacc taagtcagta catacattta gcatcagttt
    14941 ataattttca aactccttag atgttaataa atttacatct ttgtctcttc ctttgtattg
    15001 ctctatacca tctttaaaat gctctttata atagtactta tcaatattta gtggattttt
    15061 accaactctt tttttagcat cttcaatggc tttctttctc tcatatgacc aatttattgg
    15121 tctttttctt tttgttgctc tctttttatc tagcttaatt aatcgtttat aaagaatacc
    15181 cttttcttta agagctatac aatactttct tccttgaaaa taaggctcta aaagcacctt
    15241 ttcagctttt tcaggaaatg tcttaggctc atatagctta gcatataatg cttctgcttt
    15301 atactcgtca cttccccata ataacttact tgattttttt gcatattcaa tcttattttg
    15361 tttagatatt tttggattat ctaaaaatcg ataaaattgt attggtgaaa atctagactg
    15421 ataatggtga cttgtgactc cgtctttttc cataaaccat tgcatagaaa ttaacaagac
    15481 aactttctta ttatcaatat taggattcat acttcctaat attgcagcat cttgtaatgt
    15541 ctgagtatag gctctcccaa ttgcaaacac cttattttta ctcctatttg tattaaaata
    15601 gtactttgga tgttgttttg ttgaattact aagttctgat gaccccaaaa tcataatatc
    15661 cttttctctt aaaaaatgat tatttgctgt aaccccttta tcttttatat cacttaaagt
    15721 atcatccata attggaagta gatttttctc cctcaaaagt tcatcagttt tagaatcaag
    15781 aaatttgtct aacccaaata aaaatactac gcctattata aaaggtgtaa taaagtatat
    15841 caattttctc atattttctc tcctctaaaa atattcaaat ttatgttatt attaatcata
    15901 ttagttttga tatgtatatt caactacaaa attgtaataa aatcgtcaaa actttttttg
    15961 atactgttac aaaattgtaa aaaaaaagaa aaaaacgcca aaaataaatt tctttttagc
    16021 actttttcat acttataatt tgacatttta acacttggtt aagtatacac cttaccttaa
    16081 cttaaaatta aatttattta agaatatata ttataaattc ttatattttc taatataaac
    16141 tatatactat cagctggata aacaatacta ctttgtcttc ttatctcatc cataatttcc
    16201 attactatta ttgaattttc atgagaattt atatttgatt ctattttatt gttatttata
    16261 agacttataa actctacaag ttcataatac attccttcta tttctctagg cttttcctct
    16321 gctttttctt ttggaataga tatatcttct tctcttccat ctctgtattt aataatagct
    16381 ttttcaaata gattaagctt ttcaattatt atacttccct cttctccctg tatttcagat
    16441 ggtatataag aatcagctac tttagaatac tgaattatcg catccatatc atcatattga
    16501 aatacagctg aaccttctcc atccactcca gtttgaagta tatgagaaac tgcctttaca
    16561 gtttttggag caccaaataa attcaccata ggatgtatac aatacactcc tatatccatt
    16621 aaagctccat ttgacaactc ttttttaaag gcattttcta taattccatt tttatattta
    16681 tcatatcttg aagaatactg acaatagctt ccaaaaaatc ttcttatttt ccctatttta
    16741 tacaagtttt ctttaactgc tttaaagttt ggaacacatg taattctcat agcttccata
    16801 agcaatacat tattatcttt ggctgttttt atcattgatt tgacttcttt taaattagat
    16861 gctaacgact tttcacaaag cacatgtttt ttgtgtttta aacaagtaat ggtttgcttt
    16921 gaatgtaatg catttggaga agctatgtat acagcatcta tatccttcga tttagccatt
    16981 tgttctaaat catcaaaaaa aatacttgct ccatatagag ttccaaattc tctagctttt
    17041 tctaaatttc tagaatatac agcaaccaat tcaaagtctt taaccctaga tgcagctctt
    17101 agaaatatat ttgctatatt gcttgtccca acaataccaa atcttatttt acccatcata
    17161 aatcactccc cattttctac actttatttt aattttaata aaaaacttta caacttatag
    17221 atatattata aaataatttt atcaaataaa aaagaaagct aattttaaat gatttcacca
    17281 ttttaacata gctttctttt aactacaatc taaattcaac ttatattttt aaagttatct
    17341 ttctactata tctttatttc ccctcaaaaa ttttatagta agaatttcat ccacaaacaa
    17401 tgttactaaa agtatagtta caacaattgg ccaataaggt attataagac tatataaact
    17461 atcaactata tacacttgaa aatatctaac tccaataaat gtcaatatag tccaatatac
    17521 agaaaacttt agacatacta ttcctctact attgtactta taatctgaat aatcccaata
    17581 gaccttatta aaatatactt tcataagtat tcctgtaata tattctacta ctgtcggcac
    17641 tactagacat aataaaagca atgcaaatat attattgggg tcaataaatc ttgagacctc
    17701 tattataatc gacattgcaa ttgcatacat tggtttaaat ggaccattta aaaatccatc
    17761 ttcttgaaaa tgcccttgtt tataataact atataagttt tcaattatcc aacctataaa
    17821 accatacaag aaaaaattaa ataaaaaata taatagagaa cctacattat ccatgaatat
    17881 tcctcctagc tgtttatact tattttttct catattcatg gatttattct aaatcaaaga
    17941 aattatattt aatttattta attaatactt tatattatag attgtgacat tctttagagt
    18001 tcaaactttt taggtattct ctaacttcca gtaaattttc aagtatctta tgtgattgtg
    18061 atttaatttg ctcatctggc tcttttaaat ctggtacatt tatacatctt ataccaccat
    18121 tgtatgcagc ttcaactccc ataggcgaat cctctatgac aatacaattt ttgggattaa
    18181 catttatctt tttagctgct tttaggaata tctcagggtt tggtttcgag tttacaacat
    18241 catctccaca aactatagca tcaaagtaat cttttaaatt tgccttagct aatctcttta
    18301 ctgctctttc tctctttgtt gatgttgcaa cagccatttt gtatccattt tcctttaaaa
    18361 aagagattag ttcattgact cctaatttga taggagctcc cttcctctcc ataaattcaa
    18421 tcatattttt agttttttcg tcatataaat ctattattgg tacagaacta tcgtatatat
    18481 ctgtaagacc ttctattatt cctttacgat ttcttcccat aactgatgta taaatttcct
    18541 tagtcatagt atatccatac ttttcaaacg tctccatcca aaattcaaga gaaattctct
    18601 ctgagtcaaa caaaactcca tccatgtcaa aaataattcc ttctactttt tgcatacaat
    18661 tcctccaata ttttttgata taattatatt acacttttta tgattaattt tacaaccctc
    18721 aatttatcca attctaatat tgtaaaattg taattttcaa aagttacact ttggtttact
    18781 ttaatatttg aaccaagcat ataggatatc catccaccta tactgtcaaa tccatcatgc
    18841 tctatatcaa gtccaaaata cttattaata tagttgatag attcagttcc atcaactaag
    18901 taagaacctg ctcctatttt cttaatatga gtctcttctt tatcaaattc atcttgaatt
    18961 tctccaacta tctcttctag tatatcttct attgttacca caccagatgt accaccatat
    19021 tcatccacaa ctatagcaag ttgaagtttt tcctttctta ttctctcaag agctttatct
    19081 atagttaaat tttcagatat atatataata tctctcaata tttcttctag ttcaatttta
    19141 ttttcattta tcttttgatt gtataaatct cttatatgta caaaacctaa tatatcatct
    19201 ttattttttc tgcatactgg atatcttgta acaccttcct cttttaaaat agctaatatc
    19261 ttttcttcag aatcactttc atatatacat accatatcag ttctaggaac cattatctct
    19321 ctaattttct tttcttcaaa ttcaaaaata ttatcaacta atctttgctc tgattcatct
    19381 ataagtccac ttttataact ttcttctact aatagtctta tttcgtcacc tgtatggggt
    19441 tcatcaacct catcagcttg tgaatatcca aatggtttaa gaaataaatc agtacttaag
    19501 ttgaaaaaat atattattgg atatgttaac ttataaaatc ctactaataa aaaagatgta
    19561 ctcaacatta ttttttctgt attataaagt gctaaagctt taggaaccaa ctctcctatt
    19621 acaacctcca tcattgttat aattaaaaaa gaaatggaaa ttgatatagt atatataata
    19681 ctttcactaa gattaaatac acttactatt ggtaaaatta actctttaac tgtagattct
    19741 cccatccaac ctaatgcaag tgaacaaagt gttataccaa gttgacatgc agaaagatag
    19801 gaatttaagt tgtcttttat tattttacat ctttttgcat tattattacc ttcagttatc
    19861 atggtatcaa tcctagaact acgaagtttt accatagcaa attcacaagc tacaaaaaaa
    19921 gcatttatca aaacaagcat tactataagt gttactttta ataactcccg cataaagtat
    19981 aggttcttat aatgtaagaa atctataaga actcaaagtt ccccccttat attaataaat
    20041 ttaatttata atatatattc tatcatattt attaatatat cctactttat tacaaataat
    20101 ttttataaac taaataaccc cttttaatat ttatgactgg ctatttgata aatattaaag
    20161 gggttattta gttatcattt tttatttcta aaaatctttt ctcaaatgat ttagttatct
    20221 atttatccaa ttctttacat aatttaatga ttaaaaatat taattttttc actataaagt
    20281 ataaatatta tctgattatt aaaataaata ttaatactat aaataaaaac gaagcatgat
    20341 ttttatttaa ataaatctca aacttcgtct ttacttactt agatatttat ttactttcta
    20401 aatcctatta tttttaaaac cttatctttt taatacttca ccacatttat tctcagtaat
    20461 ctctccattt tccaacgcaa tttttccatt tacaattaca tattcaacac cattggctag
    20521 taattgtggc tttgaaaaat caatatcttc tgacctagaa taactatagt tatccatgtc
    20581 aataactgct atatcagcta tcaacccttc tttaagaata cctctatttt ttattttaaa
    20641 ttgcctagct ggtaatgaag taactcttct tacaatctct tccaatctaa caccagactt
    20701 tctgtacata ttgaagaaaa ttggaaaagc tcctcttctt tgtagttcaa accatgacat
    20761 atccccaccc acactaaaca aacaatctga accaaccata acaaatggat tatcaattat
    20821 tttatcatca tgtagtttat ctgggaaatc agctctatac attcctccta aacaaaagat
    20881 aagttcttcg tctccatcta aaagtaaatc gagtaataac ttgtcttcat ctattccttt
    20941 ttgtgtagct atttcacgta ttgatttctt ttccatatta atatctttag tgtttagaag
    21001 tattatactc cccctatctc caagtataaa tgcttctttt aatataagtg ttcttccctc
    21061 ttcatttcta agagcatcca ttaccccatt tatacctaat tcaaatagac tagatgatat
    21121 tgccataata aattgaatta ctcttttttt cttcatacaa tgcccagaac ttcttggtac
    21181 tgtgtcaacc attatttcaa caccattata cctagccttt aatatctcat caaatgcttc
    21241 tatttcaact ggacttaagt gagatacttg aaccctagca ccactttttt gcccaacctc
    21301 tatggcttct tttactgcat tatatcttcc tatgtaatct ctaatatgag atgtatatat
    21361 accatcatgc tctttaatct gctttgcaat atcaacaagt tcatcaatat cagcatactt
    21421 acttggtata tatgccaatc cagtagatat tccaaaagca ccacttttca ttccatcatt
    21481 tattatatct gtaatttcat ttttttcctt ttctgtagga ggtctatcct tagaacctcc
    21541 cataacactc catcttatag tcccatgccc caacaagaat cccatattga cagaaatacc
    21601 acttttagat ataaggtcac aatattctgt aaaattattc caacatttat ttttatctat
    21661 aagatacttt ttttcttctt caagtaatag accattttta tacatatatt catatacatt
    21721 ttcagaagaa tatggtgtta tagaatgtcc acaattacca tttatagttg ttgtaactcc
    21781 ttgttttaga aacttttcaa atttaccatc tagtattgct actatttctt catgaacatg
    21841 agggtcaata aatccaggtg ttataacttt tccacaacaa tcaatctctt tatttgtatt
    21901 gctatttatc ttagaatcta tttttgctat taagttgtct ttaattgcta tatctccata
    21961 aaaaccagga ttacctgtac cacctattat aaatccattt tttaagatta aatcatatat
    22021 caaaatattc cctccttaaa aaccaatttt taaataatct taatgtaatt tttatatttg
    22081 aaaatcaaat tattatattt catatttgaa aattcactat tatttcattg taattagtca
    22141 ctaagcttat ctttatacat agctcttgca attaacatag taccaaatac acatataaga
    22201 actactagag actgtggtat tataccttgc tttgataata taatagtcaa tacagatatt
    22261 acaattgcta ctaggcctaa ttttttatct tgtaaaaata cttgtccaaa aactgaccca
    22321 aatagagctg gtaaaattaa gtttaatttt tctactactt cagctggaat tttagatagt
    22381 acgcttcctc ctaaaattac ccctatagtt agtatactta tattcactaa aatagataca
    22441 gctattccta ttgtagatat tatcgagcct tcttctgtac ctgattcaac ttctgctgcc
    22501 ttttgagctg ctattgaaca tggtagcctc atattagata tattaccaga aagaaaactc
    22561 atataagttc ctgggatacc taagattggt gaataagaaa ctggttctat tatgtaattt
    22621 ggagcactca tactgacaat tgccattgta cttgctaata atgctgatat tggaggcata
    22681 ataccaaatc caaagctcaa aattattcca ggaactaatg ctgctataat ccccaaagat
    22741 agtgttagtc ttccatacct tatcttaaaa ggtaaatatt cttcattgta tatagatttt
    22801 actttactca taaaactccc cccttatatt actgaagcta ttatcattcc gctaaacatt
    22861 gatattgtaa gcccccactc tcttaaccat tttatatttt tcttcttttc aagcatacac
    22921 aatattacca ttatagccat tccacttata catgcaattg ttccattatc aaaacgcaac
    22981 accctatcag catttagata tgcaaatgaa cccaacattg ctcctagaga tattattggt
    23041 ataaatgatt tcttgccact agatataaca ttggttatct tatctagttt atgtccaaat
    23101 agtaatgtga atattatcca tcctaaagaa cctaatatca tagtccaaac tgcatttgta
    23161 aatgcaagtt ttgtcatttc aggagaacct aaagttatac ctaatgcatc tgttccaaat
    23221 ccggctgaca ttgattcaaa aattacagaa cctataaatg ataatctcat ccatgctata
    23281 ggcccaccca tagttactat aagcgatacc attccagcaa atatagtcat tgaaggccca
    23341 atagctgaaa tagcactact cttaacagct gactttattt gtttatctgt tattcccatt
    23401 gttttaccaa ctttgcaaga ttttatagca aatataaggg attgtaccac tactattgat
    23461 actgctactg tactcgctat ccacaaaagt ggatgattag ctaattttaa ataatccatt
    23521 tataaaacct ccctataaat cctcaaattt tattaatatt tctaatatat ctatttccaa
    23581 acctgtttta gtactctaag tatatttcca cctagtacct tctctatttc ctcatcacta
    23641 tatccatgct ttactaaata tctaacaatg ttttttgaag tttctgttgg gttctcaaga
    23701 ccttttacat attctacttt gggatgttct tttgttcctg ttattttttt tatatcaaat
    23761 ttagcagcta gtactgagtg taattttaca tggtcgccat atactgtatc tggtccaaaa
    23821 gctacatggt ctattcctac taaattttta atatactcaa aatgttccat aaatgactct
    23881 attgaatgtt ctttattctt ctctgttatt gtagtatgag gtgctgcttc tacacctata
    23941 acccctcctt ttttagcaca tgctattaat acttcatctg gagttagtct ctttgtgttc
    24001 cataaacttc ttgccccaac atggcttaat attattgggt ccttgctata ttctattaca
    24061 tcaagtgtag tttgaactcc aacgtgagag caatctattg ccattccaat tttattcatt
    24121 ctttcaacag ctttttttcc gaaatttgta agacctccat ctttctcttc ttttagtcct
    24181 gaacctaatg cattggattc gctatatgtt atacccatta accttatacc aaatccatac
    24241 agtatatcta ttctatcaag ttcattttct attggtgctg caccttctaa tgttggtatc
    24301 aatgctactt taccttcact tttagctctg tatatatctt ctactttttc gcactttata
    24361 acaaaatctt gatgagctaa atcacatagt ctcatgccta aatctattaa tatatcatcc
    24421 catttccacc ctgaatttga tgttatcgta catacaccat ccattaaatt atcaaatata
    24481 gcatcataat atcctcttga taatgcttca taagcacatc tttgtttacc ttccctatta
    24541 tattcaaata tatctctttc taggtgttct ggaaataata ctggatgttc atgtaatgat
    24601 ataaatattt tttcatccac tatactttta accttagctt cttgaatatc atctaattca
    24661 ataaggtatt ctttaactct tttatctcct ttacacatct caatagatga aatatctttt
    24721 cctttttcta aataactata ggcttcatat cctttgtaag ctgacttcat aacaacatcc
    24781 tccaagttct acaatttttt atatttttcc tatgtagcaa ttgatgtgcc aaaatataaa
    24841 ttttaattgt ataataaatc ttgcaaaaaa taaaaacagt agtaaggttg atatttacta
    24901 ctgttttatt aaaaataatc ttcttagatt atttattcaa tatttttgaa ttatcttaat
    24961 cttaaagata attttattta tttctatcca ttatagggat ttttttaggg tgttttgcct
    25021 ttttagtccc ctatatcact cccttaattt ttacatatga tataaagttc tttccttcat
    25081 cagttataaa actaccttgt ttttttactc cagataaaag taaaccatgg ctctttaact
    25141 tatctattct ttttctaatt tggtctacac ttaaaactat atctttttct tttaaaatct
    25201 cttgcagttt atttcttcct aataatatat ttttattatt ccaagtttct atactggtca
    25261 atatacatat actttcctca aagaaattag attgtttgaa atctaagata attgaatcga
    25321 aattttcatt aactaaagta ttgttttttt caaatctaaa ttgttctggc aaatgctcgt
    25381 aatctactct atcttcctca actatagtat caatataata aattaaattt ttaagctctc
    25441 ttacatttcc tggccattca tacaatgtta aagcttgcat tgattcctct gtaaaacatt
    25501 tgttgctatt tatttcatct aaaaaatact tacttataag aggtatatct tccttacgtt
    25561 ctctaagtct aggtatctct atatgtaata cattaatcct ataatacaaa tcttctctaa
    25621 aagaaccttc tttaattttt ttctttaaat ctttatttgt tgcagctata attctaacat
    25681 ctattggtat aattttactt ccgcccattc tcataacttc tttttcctgt aatactctta
    25741 gcaatctctg ctgtacatct aaagatatat cacctatctc atctaaaaaa attgttcctg
    25801 tatgtgctct ttcaaatata cccatttttc caccttttat tgctcctgta aaacttcctt
    25861 catcatagcc aaaaagttca ctttcaataa gtgtatctga caaagaagat agattaactg
    25921 caacaaatgg cttgtttttt cttagagatt cattatgtat tgcctgggca aatatttctt
    25981 ttcctgttcc attttctcca agtatcaaca cagaaaagtc tgtagttgct atttttcttg
    26041 caatattaat tttttctttt attattttac tctcacctac aacactctca aatgtatact
    26101 ttgatacaaa accttttgac tgaagtttat tttgaatctt gtcctcaagc acttgaattg
    26161 cacttatatt tttaatgctt ataatactct ttattcgttc attattttca taaacattta
    26221 ctttattaat tatcagtttt ttgttattta aatttactac ttcatcatta acttcatctt
    26281 cttgaaaaaa tatttttttg acaaccttat cactaaataa gtccataaag ttattagata
    26341 taatttcatt ttggtctatt ccaactagat tagaaaatac tttgttgcaa tatataaatt
    26401 ttcctaattt atcaacagaa gcaatacctt catctataat ctccaaaaaa ctcttcatgg
    26461 ttttattcat agttgtataa tacctatatc cacttactgt atcttcattg tatttttcct
    26521 taataatatg tagtttatct atagatatat ttagttttgt aaagatttct ataactgtat
    26581 ttatatcaat taccttatca cctatgtcaa ttatttgctt tatgttttgt ggtatgctgt
    26641 ttctgcttcc cgtaataatt ccaatctcac atttagattt atcacaacct ggataatatg
    26701 gtattagatt aatatgaatt aatcctagtt ttctaattat cttggcagtt tcatctgctg
    26761 attctttata agcatctata accataacat cagaatcatt ttctatactt attatctgat
    26821 ttatattttc aatatttata gtacgatgta ctattacaat aggtatattt ttatcaatat
    26881 tattatgtat atattccttt atatcattgt ctgaacatac tacaagctca tagcttgaca
    26941 gttcaatatt tatcctattt acatatacca agttatctat attacaaaat tctccaaata
    27001 tattttccaa ttgttttgat atatctatat ttattttgtc atcagttgat acaaataaaa
    27061 tattatgttt tttcatagtc ccacctcctg tttaacgagt atagaaagta ataatttggt
    27121 ctattgtagc actttttaaa aaagttttaa atcttaaaaa tcaaattttg taccatttac
    27181 tattattttc cataataaaa taatgtaagc tatctttttt cacatataat ttaatttcta
    27241 aaacggttag tttgacatta ttggaatata aacaaaaatt taatataaat tcgttaatat
    27301 attaatacat ttttaagaat gacaaggaat aaattataac aaattttagg aatatataat
    27361 aatagggtct cagaacttag ttacaagttc taaaacccta tttgtttagt gtaaaaaaca
    27421 tcataaaatt tagcttaaat cttttcacat aatattactc tttttctaag tgataataaa
    27481 atttatctat tcctctaaaa actgtaaaaa tttctgatta aatagtttaa gctcatcata
    27541 gaatatagca tgaccactat actcaaaagt atataaaatt gaatcttcta ttttttcatt
    27601 cataaaaact gcaaattcat acggacatat ttcatctaat ttcccatgaa atataccagt
    27661 aggcactctt acacatttta aatcattaaa taattcttca tctcttaaag atacagcagt
    27721 tccaatagtg ccaatacctg atgcactaaa accaatatca ttaaaccatc ttctaaagct
    27781 ttctggtgga tttgatgcaa atactttttc gccaaaatcg gttaccattt ctggtctatc
    27841 agtacatgct tgtgctatca atttatttac atcttcacgt gtcataccat atggaaattc
    27901 tggaggtctt tgtacaaatg atggtgcagc agctgcagct aataccaatt ttgacactcc
    27961 atatccatta aataaactca tatacctaag tacgattgct cctcccattg aaaaaccaac
    28021 aagggtaaag tcttttaatc caatagcatg taccacctta taaatatcgt ctgctaattg
    28081 gctataagta tatcctcctg atgttgcatc agatttacca aaacctctta aatcaattga
    28141 aactgttcta tatccgagtt ttggcaatat atttgtttga tattcaaata tcttatgtcc
    28201 taagggccaa ccatgtataa aaagtacagt ttttttagca ctcggattca aatcatatac
    28261 tgctatgttt atatcattca catatacata atacatatca acagcaactc ccttcaagaa
    28321 aatgtatgat ggttatttta tatatatgaa taaaatgatg aataactaaa ttttcaaatt
    28381 tatttacaat acttctctat tgccttttca aataaactta catgaagttt ttcatctagg
    28441 attattctat ttaatatagc ttttatataa gggtcttcaa taagacttat atctttataa
    28501 taattattaa tagccacatg ctccaaatgc aaatctagtt ttaatctgtt acaaatagaa
    28561 tttccataac atacaaaacc accattccaa tatgcaccac aagaacttgt agaacctcta
    28621 tatacaggat ttccacccaa taatcttata gtctttgcta atatctccat atgtaacatt
    28681 tctgttatag atatatttat ccacatttca cttaactctc tatgcgtttc atctaaatca
    28741 aaattatggt atagatattg atttacactc gtaaattcac ttgatactcc ggcatagtca
    28801 tccatcaata attctgcata atacttattt ggacctaaaa cttttatctc tggatatggc
    28861 tcatcacttg aatatccatt tcgcttgtgc atgtcataat gtgcatcact cataatatct
    28921 cctcctttaa atttaataca tgatattaat tgtatgcatc acgacttttt catataactt
    28981 agataataaa atctacttaa ataataaaaa gccatattaa ttaaaattaa catgaccttt
    29041 tatccacaaa attacttttt aattattcat cttttccagc tactgatagc tctttaataa
    29101 caactgaagg tgaacctata ctactcattg gaaattctaa atcttcccct atagcttcaa
    29161 tatctttcaa caggtcaaaa tagtttcctg ctactgtaat ttgctctact ggaaatactt
    29221 tttttccttc tttgatataa aagcctttgg cagctaaaga aaagtctcct gttactgaat
    29281 ttgcacctga atgaagtcct gcaaagctag taaccatcaa tccttcatct atatccttta
    29341 taatttcatc taaagattta tctcctttct ctatataaaa attagttgga tatatgctta
    29401 taggtgatga atatgaagat tttattccat ttcctgtagt ctttacacct gccttattag
    29461 ccgtttttaa gttatgaagt aaagttataa gctttccatt taaaacaact tcttttttaa
    29521 atgtagctac tccttcatca tcaaaaggag tagatgccat accattttct aaaagtgggt
    29581 catcaactat tgtaactata ggagatgcta tcatgtctcc ttctctattt ttcaataaag
    29641 ataatccttt ttgagctgaa tctgcattaa atatcccaga aaatgtgcta agcaaagata
    29701 ccatagcttc attaagcaat atagttttat atttacctga tggaatactc ttaccaccta
    29761 ctttagataa agcattatca acaccaagtt ttgctatctc acaaggtttt atttcttcaa
    29821 tagaatttgc tatattatat cctattccat catatttttg tccattgtct tctatgatag
    29881 gaactacaaa ccctataagc atattagttt tattgcttaa attaagacct ttagtattag
    29941 atataccatt acttgataca gaataagata tagtacattt agataaattt accaccttat
    30001 ctgaataagc tttagtctct ctttccattt ctaaagctaa atcaatcaac ttatctgcct
    30061 ctaaattttc tagctcttta gaataagtct ttacatcatt atagtgctta tctccttcat
    30121 atataaattg tacatcttca ttttcaatag tgtttactcc atcttttaca ttttttatca
    30181 acatatcaac agctttatca tctaaaattt ctgtataaga ataacctatc tttccattta
    30241 ccttacctct aaaagataaa ccaaaagatt tatcaagatt gtatttctca acttctcctt
    30301 catatatatt tatacttaaa ttttctcctg tataataata tatttcatac tcttcaaaac
    30361 cttcacttag agccttttta aataatatat ctttaaaatt tttaagttcc acaattatcc
    30421 ctcctatctt ccacctacag taatttcttt tacccttatc ataggttggc ctacattagt
    30481 tggtatactt cctgatgatg agccacacat cccctgagct tgttttacgt tattcccaac
    30541 catatctata ttcataagta tatcgctacc ttttccaatt aaactagcac ctctaactgg
    30601 ctcttgtatt tctccatttt ttattaagta accttctgaa actgcaaaat taaactctcc
    30661 tgttacagga tttacagaac caccacccat ttttttagca taaagtccat ctggtattga
    30721 ctttataata tcttctggtc tatcttctcc agcagcaata taagtgttag tcatccttga
    30781 agttggtgca aatttgtagt tctgtctacg agaacttcct gtaggattca ttcccattcg
    30841 tctaccatta agtttatcta tcatataaga cttcaaaatt ccattttcaa tcagtatatt
    30901 cttttgagtt ggatttcctt catcatctat attcatagaa ccccagtagt ttggtattgt
    30961 accatcatct atagctgtaa tctttgtgga agcaatctgt tgacctaatt tatctgcaaa
    31021 tacagagttc ccctttgcaa ctgatgtagc ttccaaagaa tgtccacaag cttcatgaaa
    31081 tattactcca ccaaatccat tatctattgc taccatcata ttacctgcag gacaattttt
    31141 agcatgcaac atagtatgcg ctactctagc tgattctttt gcataatatt ctgggtctat
    31201 ttcttcaaat atttcaaacc ctttacaacc cccaggacct tcaaatccag tttgattttc
    31261 attaccctta gatgcaattg aacttatccc tagtctggtt cttattcttc tatcctcaac
    31321 atatatacct tcagtgtttg caattaatat tttttggtct ttatccaaat agctaacact
    31381 tacttgagat atatcattac taaattcttt tgcactctta tatgcaacct tcataacact
    31441 tactttatct ttatttccta ttgaatttgg ataaattttt atattatgta tgttatttat
    31501 tttaatactg tcatttaata ttacactttt tccatcttcc aatttaccta aagcaacagc
    31561 agctttgtat gctacatcca acagactatt taatgaattg tcacttgtat aagcatatat
    31621 acttttcaat cctttaaata ttcttattcc tataccataa tttcttccac ctattgcatt
    31681 ttctacttta ttatctatta aactaataga attatttata gtgtcttctt caaaaatctc
    31741 agcaaaatct cctccagtaa ttagacattt ttctaatacc ttagaagcta tattttttga
    31801 aagcataaat ttacctccta ctttaaattt ttaattaact tttattcaat ctttttactt
    31861 gttaacaaac attatatact atattactta aaataaggta attatgaata tattatacat
    31921 atgttttata ctaaaatgtt atcacatttt atctatacat acccatataa ctagataatt
    31981 aaaatgtata atattatttg ctatagaaaa taatacactc atacataata aattttagga
    32041 gtgaagtata tgaatcaaga atatgtaaaa ggaaatccta tttttaccaa tattaataaa
    32101 gttccaagac aatttccata ccttactgat gatattgata ctgatgttat aattgttggt
    32161 ggtggcgtaa ctggatgtat ttgtgcctac tatctagcta aaaacaatat aaagtctgtc
    32221 attcttgaaa aaggaaggat tgcacatgga agcactagcg tgacaacttc tctattacag
    32281 tatgaattag atgacaattt gatagattta acagaggtta tgactctaaa agatgctcta
    32341 aaagcatata acctttgtac ttcagcactt gaagaattag atacatttat agagctatat
    32401 ggaaataagt gtgattatgc caaaagagat actctacttt atactgccaa caaacttgaa
    32461 gttaaggcta tcaaagaaga atataactta agaaaagaaa atggatttga tgttgaatat
    32521 attgatgaat ccacaaaccc ttttaacttt gatttaaaat caggattgat agcaaagaat
    32581 ggaggacgag aattagaccc atataaatat agtcaccatt tgattgatgt aagtttaaaa
    32641 aatggtcttc aagtatatga aaatacagaa gtaaaaaaag tagatttatc aaatgataag
    32701 gttactgctg aagtatcgta tggatacaaa gttcatggta aaaaattaat tgtagctaca
    32761 gggtacaata caagtttatt tacaaaaaga aattttgcaa ctaagtcaaa tacttttaat
    32821 atagcaacga aaccacttaa aaacatagct tcttggaaaa acaacatttt aattagagat
    32881 aactgtgacc catataatta tctaagaact actaaagaca atcgattaat tataggtggt
    32941 gaagatgtaa gttttgatga tatagaaaat gaaactttag ccaatgaaaa gtatgatatt
    33001 ttagaacaaa gattgaaaag tatgtttaag gatataaaag acattgaagt tgaatataaa
    33061 tattgtggtt gttttgcttc aactttagat aatttaggtt ttattggtcc agataataaa
    33121 aataacaatc tatggtattg cttaggttat ggagcaaatg gtatactctt tgcaatatta
    33181 ggaggtataa tgttaagtga attatatctt ggcaaacaaa ataaaaatat gaaattattt
    33241 aaagtagata gatttgataa atagatatta tatattaaaa gactgtaaaa agatgaaact
    33301 ttataattct aaaagttaac tttgatacag tcttttataa tgttcctttt aaaaatactt
    33361 tatttataat taaatataaa gtaaaatgtt aaaatataac tgataaaatt tagtcataag
    33421 ataatattta agtttatttg atgaaatatg gaggaattat tatgaaggaa atactcgtta
    33481 ttgctcccac taaaggaacc tatgaaaaat caattcacat agttaaaaaa aacaaatata
    33541 caaatattga tgttgtattt ggcaatctaa aagaaggtat acctcttgct gaaaaaagta
    33601 ttaatcatgg tactagaatt atcataagcc gaggtggaac ttacaatatg ttaaaagcta
    33661 cttacaatat acctatagtt gaaattaagg tagatgctta tgatattata aaaagttaca
    33721 aagaggtaaa aaattccaac gaaccatttg gaataattgg atttaataat gtcatctacg
    33781 gtttcgatat tatagaagaa atattgaata agaaaataac tatgattgaa attgaaaaag
    33841 aagaagaaat ttatgatgct atagaaaagt acagaaagaa aggtataaac acatatatag
    33901 gagataccac tgttgcacat attgttaaga gacttaattg taagggaata ttaatcgaat
    33961 ctagagaaga aaacatactt agagccattc aacaagcaga acaaatactc gaagcaacca
    34021 aggatgaaca aaaaagaaga ttacagatag aagctatgac agattttgta catgatggaa
    34081 taataacagt tgataaaaat tttaaaataa cattatttaa taagagtgct gaaaaaatat
    34141 ttggtataaa aaaagaaaat gcactttatc ataatgttgt agatgttatc ccaaacacag
    34201 ttcttccaca agtagttgag actatggaac ctcaaattgg tgaaatacaa aatataggga
    34261 gtacaaaaat tattacaaat agagttccaa tcattgttga tggtcagatt caaggggctg
    34321 tttcaacatt tcaagatagc aaggagataa gttcttttga acatacaata agaaggagct
    34381 tattaagcaa aggtctatct gctaaataca cttttgatga tataattcat gctagtgaaa
    34441 agacaaaaga ttgtatagaa cttgcaaaaa aatatgcttg ttatgatact cctatgatta
    34501 ttactggaga atctggagtt ggtaaagaac tattttgtca aagtatacat aactatagta
    34561 agcgtaaaaa tgcacctttt gttgctgtaa attgtgctgc catacctcca tctctaatag
    34621 agagtgagtt ttttggttat gaggaaggtt catttacagg tgctagaaaa aaaggtaaag
    34681 caggtgtatt cgaactagca catgaaggta caatcttcct agatgaaata agtgaaatcc
    34741 ctcttgaact tcaaggtcga ttattgaggg tattgcagga aaaacaagtt atgagaattg
    34801 gtggtgataa agttattcct atagatgtaa aaattatctg tgcttcaaat aaagacttaa
    34861 aaaatatgat gcgcaatggt ttatttagac aagaccttta ttttagaata aatatactaa
    34921 cattatatct tccttcatta aaagaaagaa aagaagatat tataaaatta tcagaatttt
    34981 ttatacataa atattcaagc aaatacaata aaacgccttt aattatcact ccaaatatta
    35041 aaaaggcact tcttgaacga gaatatgaag gtaatataag ggaattggaa ggtatgatgg
    35101 aaagggctgt tattgtggaa tcatttgact cgattttatt agaaaaggtt agcaatgaat
    35161 atacaaataa tatagttgat aaagataata gtgattttga atgcagtaat ttagatttaa
    35221 aaactttaga a
//
LOCUS       DAEPKC010000033        34904 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.033, whole genome shotgun sequence.
ACCESSION   DAEPKC010000033 DAEPKC010000000
VERSION     DAEPKC010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 34904)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34904)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34904
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.033"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(441..2828)
                     /gene="cadA"
                     /locus_tag="KR294_001665"
     CDS             complement(441..2828)
                     /gene="cadA"
                     /locus_tag="KR294_001665"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HBH0239746.1"
                     /translation="MEANNSIKKEFILGGLNCAHCAEEINNKVSKLQEVKSSNLNFIN
                     KKLTVNIKESFNEDTTIEKIIDIIDSTDPGLDIQISSKENAASKTSIKKELILGGLNC
                     AHCAEEINNKVSKLKEVESSNLNFVNKKLTVNISNNFEEDDVINKIKEIINSTEPGLD
                     IQVGSTDKVKGRTTEKSGAVNDTNKKELIPLIIGALVYIFGIYQTATGYESQFSNIVF
                     IVAYVIVGGDVLLRAIRNISKGRVFDENFLMALATVGALTIGELSEAVGVMLFYKVGE
                     YLQGVAVGKSRKSITSLMQIRPDYANLKVNSEVKVVSPEEVNVGDIIVVKPGEKVPLD
                     GVVVDGVSMLDTSALTGESVLREVEKGDEILSGVINKNALLSIEVTKSFGESTVSKIL
                     DLVENSSIKKSKTENFISKFSRYYTPIVVIAALLIAFVPPLVISGEVFSDWLYRGLIF
                     LVVSCPCALVLSIPLSFFSGIGFASKNGILIKGSNYLEALRSVDTVVFDKTGTLTKGV
                     FNVTKLNPEGISEEELLEYAAIAEVNSNHPIAKSILSYYNKKIDLDTIDSYEEIAAYG
                     IRVKHNGNFILAGNEKLMKKENISYSSAKEVGTVVYIAVDKVYRGYIVISDEVKEDSK
                     NAIRSLKEIGVKEVVMLTGDNEKVAKNIAQELELDTVYSNLLPNEKVDRLEDLYEGRT
                     EKEKIAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVLMTDEPSKISKAIEIA
                     NKTNKIVWQNIIFALGVKIIVMILGAGGVATMWEAIFADVGVALIAVVNAMRAMR"
     gene            complement(2851..3216)
                     /locus_tag="KR294_001666"
     CDS             complement(2851..3216)
                     /locus_tag="KR294_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH0239747.1"
                     /translation="MREEINDCNCNIVHEEIVTEAKSTMPDEEMLYDLAELFKVFGDT
                     TRVKILYALFANEMCVCDIASLLNMTHSAISHQLRVLKQARLVKFRREGKTVYYSLDD
                     SHISQIFDCGLNHIRETYK"
     gene            3415..4263
                     /locus_tag="KR294_001667"
     CDS             3415..4263
                     /locus_tag="KR294_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239748.1"
                     /translation="MSNKKKKDLDTSYMPYLDPANYADYITNEEIPQDELRNDPQISN
                     GYTKIPNNQNINNLYPNNVNHYPKSSNSPNNLPNTNNTSGNMNYNTSATNNMPNNMNN
                     NTGMPNNMSNNMNSNMGMPNNMPNNMNSNMGMPNNMPNNMNSNMGMPNNVPNNMNSNM
                     GMPNNMSNNMNSNMGMPNNMSGNMNNNMYGNTGMPNNMNSNMGYNMNNTMGIPNFSCN
                     QNMPPNVLMMIPGVICHNTMQGMPVVMPSTMPPNIYPTPYGSSNMSVQGIPQATNIEE
                     FDEEEM"
     gene            complement(4700..5788)
                     /locus_tag="KR294_001668"
     CDS             complement(4700..5788)
                     /locus_tag="KR294_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239749.1"
                     /translation="MNFNFAKATNSRLMGSLGLIINWIDDENNHFCQYFLLDAEGLGL
                     ADYVSLNNPTQEEAYMEEERLMGGFGSDRVELTKDESLFLVSYFGNKNLYYDKLLPGD
                     KCEYIDIIKNYKTDLTIEKLYNKICKRVDEEVEFINYMTMRFIAWDRESLKYFSGSDE
                     IANMHITNINGTLLKNVVSDKGQGRYISEALYEDNDGYYICKIAFCISKCYETGFRIN
                     SLLVTDKEPMYDFEVFDEISKSEFVSVYSVNSPEEFAGVFYRENPFLLKSNMNEGIFF
                     TRFNFNNDHVKENVYIINNDMKAIYYLMGNKFFIGTYNENDCNYINEISQSNYSDYIK
                     FEEKFFFEQNALYDFAESGSLDFDDFLE"
     gene            5913..6641
                     /locus_tag="KR294_001669"
     CDS             5913..6641
                     /locus_tag="KR294_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family hydrolase"
                     /protein_id="HBH0239750.1"
                     /translation="MKNIAAFFDIDGTLYRDSLMVEHFKKLIKYDIIDQKNWYKHARD
                     TFMDWDKRQGNYDDYLLEICDLYVDSLKGLDKTCINFTSDQVIKLKADRVYKYTRSRI
                     EWHLNQGHIVIFISGSPGFLVEKMAKKYNVTDFLGSDYVFENNIFTGTVIPMWDSISK
                     NNAINDFVVKYDLDLSNSYAYGDTNGDINMLKRVGNPIAINPTKELLSQISLDEEISK
                     NVEIIVERKDIIYSLSTDVNIVDI"
     gene            complement(6843..7334)
                     /locus_tag="KR294_001670"
     CDS             complement(6843..7334)
                     /locus_tag="KR294_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239751.1"
                     /translation="MSIKVAYGGVLLALNVILLTLTNIIPVNTLFIMGLASLLVSIVI
                     MEWGFKSGIAFYIGSIVLGFIVMASKSQWIVYSLTFGIYGIVKYLIEKDRSIYIEYFM
                     KLVFANIMILILYFLLRTIVYIPINIFIIGSFEIAFIVYDYVYSSFIGYYNNRLRKML
                     FKK"
     gene            complement(7345..7788)
                     /locus_tag="KR294_001671"
     CDS             complement(7345..7788)
                     /locus_tag="KR294_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239752.1"
                     /translation="MYSNTYNNENFMRARSFIENSEFKKAYDFLKTLTDKCAEWYYLT
                     GFSAMNIGYYEEGEDFLKRAKFMEPENSEYSDALRSYTQYRNDYSNRADNYNRRRRND
                     LDGCCCCCCDDCCCCLGDDCCENCAKLWCLDSCCECFGGDLITCC"
     gene            complement(7778..8617)
                     /locus_tag="KR294_001672"
     CDS             complement(7778..8617)
                     /locus_tag="KR294_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239753.1"
                     /translation="MFGYVKINKMDLTFREYDYYKAYYCGLCKYLKRNHGEISRFSLN
                     YDITFLIVLLTAVYNPESISTEEVCIVNPFKKKKVITNDITEYAASMNILLTYYKLED
                     NLMDDKRIKDKLAYYIYKNKLKLAYEKYPEKAEYIKQQLNELNKLEKDKNINIDEVSS
                     IFGNIMGEVFVYKKDENERNLRMIGFNIGKYIYLLDAYEDLDEDFKKGRYNPFIEYID
                     KNDELKEKVKKIIVTSLGFLARGIDNLNLNKNVGIIENIIYSGVYLRYINILESRGGK
                     NVQ"
     gene            complement(8836..10221)
                     /locus_tag="KR294_001673"
     CDS             complement(8836..10221)
                     /locus_tag="KR294_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH0239754.1"
                     /translation="MDNLNKKFLMEYIDEIQGELRDISDKIWKNPELQYKEYYASNLQ
                     KECLKKHGFSIEGLEGMDTAFVASYGEGRPVIAVLGEYDALDGLSQKVSTTKEPIVDG
                     GAGHGCGHNLLGTGSIGAVIAVKELIKLKKLKGTIKYYGCPAEEDLSGKVLMIKKGFF
                     DGIDCAFSWHPFDINTPIRIPTLANYSVKFRYNGISAHAAQAPYNGRSALDAVELMNI
                     GCNYLREHIFDNCRVHYVTTNGGKMPNIVPDFAEVWYYIRGVKMEHVRDVFGRIVDIA
                     KGAALMTGTIMEYDIISGVYDYIPNTILTDILSQNMKLVGVQNYNEDDYYFADKLAET
                     VSIDKRSSVSSVLSGNKDITKMNLHDEVTDDTFTHNNCISLSLDIGDVSYIIPTAQCS
                     CSVWPIGISAHTWQSCASAGSDMGFKAMLLASKSISCSINDVMLDELVINKAKKELKD
                     TVGSFKYIPII"
     gene            complement(10394..11137)
                     /locus_tag="KR294_001674"
     CDS             complement(10394..11137)
                     /locus_tag="KR294_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoplasmic protein"
                     /protein_id="HBH0239755.1"
                     /translation="MKKVLIVGESWVKNITHIKGFDTFVTTHYEEAVKWLKEAIESGG
                     YETVHMPAHVAADSFPYKLEELNEYDCIILSDIGSNTFLLSNSTFIDCNSNPDRLELI
                     KEYVNNGGALIMVGGYMSFTGIDAKARFGETAIKDVLPITMIDKDDRVEKPAGIIPEV
                     IDSEHPVLKGIPTEWPKFLGYNKTVARDNCPVLATIGGDPFVAVGEFGKGKSAIFSSD
                     CAPHWGPKEFTDWKYYNKLWVNMLDWLTC"
     gene            complement(11157..12419)
                     /locus_tag="KR294_001675"
     CDS             complement(11157..12419)
                     /locus_tag="KR294_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBH0239756.1"
                     /translation="MKKILLDTLNSKKQEYIDYLKELVSIKTEDVGHGILGGFEKEGQ
                     EYIEKLANYIGFSVDRQEMSEELIKKAKNIYKEGNLGHNYQDRYNLICKYSDDLPGKT
                     IVFNGHVDTMPPGDISKWKYNPYRATEDNGKLYGLGTADMKSGLIASILAVKLIKDSG
                     LNVPGNVKIMSVVDEEGGGNGTINAVMNGIDGDCCIICEPSEQNLIVAHMGFVFFEVE
                     VKGVSLHCGSKWEGVNAIEKAMLLLQDIKELEHNWLMIYKHPLLPSPTINLGVINGGT
                     AGSTVPDKCVFNLCVHFLPNIMSYEQVVNDVTNVIMTRANGDLWLKDNKPNINIYQSG
                     LGFEMDKDSDFVVNAHKILEETLGKKLEIKGSTAGNDARVMKNLAEIPTLILGPGSIE
                     QCHSIDEYVEIKEYLDSILMYASLILNL"
     gene            complement(12603..13601)
                     /locus_tag="KR294_001676"
     CDS             complement(12603..13601)
                     /locus_tag="KR294_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose ABC transporter permease"
                     /protein_id="HBH0239757.1"
                     /translation="MSSITKHKEEKSSPLLTKLTSVFRDQGSAAVGLVIIFIIMSVAS
                     SNFLTLDNLINVGRQISINAILAVGMTFVIITGGIDLSVGAVIALVGTFWATTVVNYN
                     APIWVGMILALAIGTILGVIKGAIISTQKLPPFIVTLAMLTIISGASFVFTGGRPISV
                     NTDAFKMLGRGYIGPIPIPVIIMIIVVIAGHFLLKRTNFGRHVHAVGGNEEAARLCGV
                     KVNKVIVKVYALAGLLTALAGIILSSRLASGSPTVGDGAELDAIAAVVLGGTNMMGGS
                     GSIVGTCIGVGIIGILGNGLNLLSVSSYNQMIIKGLVMLFAIWINNIKLKKSAKSK"
     gene            complement(13585..15096)
                     /locus_tag="KR294_001677"
     CDS             complement(13585..15096)
                     /locus_tag="KR294_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HBH0239758.1"
                     /translation="MSNIILKLSNIAKEFPGVRALDNVNFELFHGEVHALLGENGAGK
                     STMIKILTGAHSKTSGKFIFEGKEIENISPDISKKIGINAIYQELTVFDELTVAQNIF
                     MGKEINGKVLTNDKKMNEEAKKIFDNMGIDINPNSLVKELSIAQKQMVEIARVLSSET
                     KVLIMDEPTSSISKKETEILFRLINDLKESGVSIIYISHRMEELFEICDRITIMRDGK
                     TISTLNTKDVSSEEELVNLMIDRKLDQFFPKRKVEIKEEIMRVENLTKNNVFNDISFN
                     IRKGEILGIGGLVGSKRSEIVEAIFGLRTYDSGKIYLNNEEVKFKTPSDAIENGLGLI
                     TEDRKGTGLFLQMSVKENTTMAGLKKISKFKSIIDRKKEKEILEKYIEALKIKTPHMN
                     QVIQSLSGGNQQKAIIARWLLLQPDILIMDEPTRGIDVNAKAEIYNLMGDLVESGVSI
                     IMISSEIPELISMSDRIMVMREGHISGFLEGEEMVENNVLKLAFGGKINEFNN"
     gene            complement(15150..16112)
                     /locus_tag="KR294_001678"
     CDS             complement(15150..16112)
                     /locus_tag="KR294_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HBH0239759.1"
                     /translation="MRVRKILSLGIAGILAIGMLTGCSMEGPSKSDNKGGSDKKDLTI
                     GVSTITLQHQFFIDIDEGIKEKAKELGVKVIVNDPDQDVAKQTSAIEDFIQQNVDGMI
                     VLGTDNSAIVPAVEGAFEKMPVVTVDAVLNTENITSYVGTVSYDAGKKLGEYTKKYID
                     EKLGGKSEIAIVTDLKSQIQMQRIDGFKDALKGSANVKILNSQPGYDREESLNTVENL
                     IQSNPDVDIIYATAENSVLGAKAALESAKNKDVKIVGFDLTEEASSGITDGTILAMIQ
                     QQPKEMGRLAVEAVVKAIKGEKVEKNIPVPALLYDKENIKDFKN"
     gene            complement(16160..17050)
                     /gene="rbsK"
                     /locus_tag="KR294_001679"
     CDS             complement(16160..17050)
                     /gene="rbsK"
                     /locus_tag="KR294_001679"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HBH0239760.1"
                     /translation="MGNIVVIGSVNMDMVCSVDKRPEKGETVLGNSFFTSPGGKGANQ
                     AISASKLGANVKMISCIGEDGLGEELIRNFRTNKVDYSLVSRNNHKSSGVAVITLCEN
                     DNSIVVVPGTNELVDIELIKKNEEEIKNADIVLLQLEIPLKTINYVVNFCFENRIRVL
                     LNPAPAVKLNEDIIEKVTYLTPNEHEYKIVFDTNEGIEEVLKKYPNKLVITEGKNGAR
                     FYDGEEIKHVSCISVDVQDTTGAGDTFNGALAVAITEGKNLYTAVEYAVVVSGLSVTK
                     LGAQSGMPYKEDVEKYLNNK"
     gene            complement(17092..18105)
                     /locus_tag="KR294_001680"
     CDS             complement(17092..18105)
                     /locus_tag="KR294_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBH0239761.1"
                     /translation="MSITIKEIGELAGVSKTTVSKVINNKDENISQATREKILKIMKE
                     KNYVPNKLAQSLVTKKTNTIGLLIPDIRNPFFTDVSRGVEDKANEEGYNIILCNTDED
                     AKKEYEGIRTLSERMIDGIIFAASSNTNWKEANYKDIKIPTVLIDKKISMNKETLKGI
                     VKINNFEGAYIATKHLLDIGNKKIIYLSGPLQNEIAVDRLEGYKKALIECNLSYNPAY
                     VFEGKYKIEWGQEFIKNLEKIDFDAIFCANDLIAIGVIRGLKERGLSIPNDISVVGFD
                     DIQTSSLISPSLTTVKQPSYDIGYKASEILINCLRGDKKESFDELIFKPELVIRDSTK
                     ESE"
     gene            complement(18333..19310)
                     /gene="bioB"
                     /locus_tag="KR294_001681"
     CDS             complement(18333..19310)
                     /gene="bioB"
                     /locus_tag="KR294_001681"
                     /EC_number="2.8.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin synthase BioB"
                     /protein_id="HBH0239762.1"
                     /translation="MEKYIIKLKNKVLREKEISYEEALNLISLDTNNKNDFDILLKSA
                     NEIREYFMGRKADLCTIMNAKSGKCSEDCKFCAQSSYYKTGVEEYSLLDYNEILNRAK
                     EMESKGVHRFSLVTSGKGMSGKEFNNILNIYEGLRENTNLKLCASLGIIDYEQAKMLK
                     SAGVTTYHHNVETCRDNFHNICTTHTYKDRIKTIKDAKKAGLDVCVGGIIGMNESEEQ
                     RLKMAFEIRELNVKSFPINILNPIKNTPMENYDVLEPMEILKTTAVFRFIIPNVYIRY
                     AGGRLSLKGYDKVGFNGGVNSAIVGDYLTTVGSGIENDKKMIIEQGFEL"
     gene            complement(19516..19779)
                     /locus_tag="KR294_001682"
     CDS             complement(19516..19779)
                     /locus_tag="KR294_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239763.1"
                     /translation="MKIYYEKENSKKANVNNIPSVFAFNFLRNFLTSKEYEETRKEYF
                     INNLTKSQVNQAMKDLKWLFREYEGLEVITMESLDGVKTRIVL"
     gene            complement(19849..20922)
                     /locus_tag="KR294_001683"
     CDS             complement(19849..20922)
                     /locus_tag="KR294_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF362 domain-containing protein"
                     /protein_id="HBH0239764.1"
                     /translation="MEKSKVYFCDLYSNSQNKNVPNNVRRLFDEAGFKDLIEKNDQVA
                     IKLHFGEKGNTTYMSPVAVRQVVDKVKDCEGKPFLTDTNTLYTGSRTNSVDHLTTAIE
                     NGFAYAVVNAPVIIADGLYSRNYENVKIDKKHFESVKIGGEIYNSSAMIVMSHFKGHE
                     AAGFGGALKNLAMGCASAAGKQMQHSDVTPVVKEKKCVGCGKCVNSCPTKAISIVDKK
                     AVIDSDVCYGCGECPTVCPTRAVTIQWESDSDVFVEKMAEYAYGAVSNKKDKVGYITF
                     VMNVTPLCDCVPWSGRPIAHDIGILASTDPVAIEQACYDLICKEMGHDVFKHEHPHVN
                     GTRIIDYACEMGMGSKEYELIKL"
     gene            complement(21181..21939)
                     /locus_tag="KR294_001684"
     CDS             complement(21181..21939)
                     /locus_tag="KR294_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0239765.1"
                     /translation="MREYIAFTKKEFKENLRNYKLFSLIILFLIFGISSPISAKFMPD
                     LIAHFAPTLKVTAAPTALDSWTQFFSNISGLGMSLTLIIFCNILSNEYSKGTLVIMLT
                     KGLSRSSIVLSKFSVTVIIMTIGFWLSFLFAYGYTMYFWPTANLNHIIFSAFNLWLIG
                     IMYISVLILGCVLFRPAFASVLLVLVATLLLSLISIPKQIAPYTPNFLMSKNIDLISG
                     KVAMPEFIIPIIITVLISIVCLLAAVILFNKKPV"
     gene            complement(21936..22853)
                     /locus_tag="KR294_001685"
     CDS             complement(21936..22853)
                     /locus_tag="KR294_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0239766.1"
                     /translation="MNIVSINGLSKGFGNRKIIDNLNFTVPEGSVFGFVGKNGAGKTT
                     TMKMVLGLLKPDSGTIDVCGEKVTYGKTSSNRHVGYLPDVPEFYNYMRPLEYLSLCGE
                     ITGLSKKEIQIRSEELLSLVGLRNEKRRIGGFSRGMKQRLGIAQALLSRPKLLICDEP
                     TSALDPVGRKEILDIMLKIKDSTTVIFSTHILSDVERICDHVAILNKGSIALSGTLSE
                     IKSMHGKDRLLLEFASNDEIQKFKSSDGIKSLLKDSEETNMEIVLHGKDIKAIQKTVI
                     STLAEMNLCPVKMELIELSLENLFLEVVK"
     gene            complement(22853..23053)
                     /locus_tag="KR294_001686"
     CDS             complement(22853..23053)
                     /locus_tag="KR294_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLDc_N domain-containing protein"
                     /protein_id="HBH0239767.1"
                     /translation="MENLMEYLPLLVPVIILDLILIITALVHVLRHPNYKIGNKAIWI
                     IVVLFISLIGPILYFTIGRGEE"
     gene            complement(23058..24152)
                     /locus_tag="KR294_001687"
     CDS             complement(23058..24152)
                     /locus_tag="KR294_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0239768.1"
                     /translation="MNELNIAKTLILKRKEKGITQDELANYIGVSKASVSKWETGQSY
                     PDITFLPQLATYFNITVDELICYEPQMMKEDINKLYNKLCKDFTVKPFDEVMDEIREI
                     IKKYYSCFPLIFRMGLLIVNHYDIVDEKKRELLISEALEIFIRIQETCNDIDICRQAK
                     SMEATCYILLNQPIQVIDLLQNSNFPMINESILLAQGQMMNGQMDEARETFQLGAYQN
                     LISLVQNLVGILQNADKLQMKEIERRILAISDIFELDTLSPAIMLSSYLTQAQINLIH
                     GDNEGAIKSLRKYVDLATRDIYPIIIHGDDFFNKLDRWISEIGTGITRDDTIVKAGIV
                     AAIKNNPMFSVLSENKEYKFLIEKLSLLEE"
     gene            complement(24662..24802)
                     /locus_tag="KR294_001688"
     CDS             complement(24662..24802)
                     /locus_tag="KR294_001688"
                     /inference="COORDINATES: protein motif:HMM:NF021468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2185 domain-containing protein"
                     /protein_id="HBH0239769.1"
                     /translation="MNGEGCILSNKITKECYKVGYMIREKSIDIYPDSGWGFMTWDEN
                     GE"
     gene            complement(25112..26419)
                     /locus_tag="KR294_001689"
     CDS             complement(25112..26419)
                     /locus_tag="KR294_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBH0239770.1"
                     /translation="MDISRSVDNSLNRTIEFLKELIKIDSQQGEPISQCPFGIGPKKS
                     LDKTLDYCASLGFSVKNIDNYIGYAEIGEGEELIGIPMHLDIVPPGEGWSVDPFSGAV
                     IDNIIYGRGVIDNKGAVSMLIHVLKNIEDMYPTINKRIRLIFGTNEETGMKCIKYYLD
                     KGEEIPSMGFTPDAMYPVVNGEKGRVHIRIEKEIKIDKSKPYIIVSGGTKENVVPSHC
                     TAKIINGIISELTTKGVAVHASNPEKGENAISKMVIKIVEDNMDFQHREDIELVSKYL
                     CSDYYGDALGINQYDEVFKNTTLNLGILKVNEEKIVCELDIRYGKNIVLNNIIDRFKK
                     VFCNGWKIEVIVHKDLHYVDESNLVLKKLLEAYEEVTDENGYTIAMGGGTYASWFKDM
                     VAFGPKFLAYKTGGHGVDERVPINHIRKNMEIYTLALIKLLEL"
     gene            complement(26484..26963)
                     /locus_tag="KR294_001690"
     CDS             complement(26484..26963)
                     /locus_tag="KR294_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-2-amino-thiazoline-4-carboxylic acid
                     hydrolase"
                     /protein_id="HBH0239771.1"
                     /translation="MSEKMYTEKEYLEGIRGATGERAVWFYLLMKEAEKLGANPDDIC
                     KEAIYGFGKMRGQKYNVADTPGKMAEMLYNSKGQKVFEMELVENTDENGVLKFHHCPL
                     DAAWKEYGLTKEERKEICRLACYGDYGRVDCAQGVKLDFAQKCAHDDEVCELVFTKK"
     gene            complement(27010..27873)
                     /locus_tag="KR294_001691"
     CDS             complement(27010..27873)
                     /locus_tag="KR294_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBH0239772.1"
                     /translation="MQEIKNKEVKNGQGPTEVNKTRVLTKKDVTKTYLRWWWTAELSN
                     SFERMQALAVCASFTPALEKLYKRKEDLVDALKRHLQFFNTQAIWGGLIHGTVLAMEE
                     EKATEGKIPGEVISGVKNGLMGPLAGIGDTLDFGTFQTIFLALGASFGAEGSVIGAFF
                     PIMFSILLFCEGYYLFHLGYSLGRDSIKKILSGGIVNKIIDGASILGMFMMGALSATT
                     VKLSTPLSFDIGGKAIVVQDTLNMIAPGLLPLGVVFFVYWGMKYKKWTITKLLVILVV
                     LALVGSFIGIF"
     gene            complement(27873..28628)
                     /locus_tag="KR294_001692"
     CDS             complement(27873..28628)
                     /locus_tag="KR294_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH0239773.1"
                     /translation="MESVLMLAIVTGLWYWFAAGLAGYTLFSTLKSPLFIGFSLGLLW
                     GDVTTGMIVGASIEMVYLGMVAAGGNIPSDKCLAALIAIPVALQTGVNAEVAVSIAVP
                     LGVIGVLVNNLRRTGNAVLVHKADKYAEEGNTKGIWRCATLYSLIFGFVLRFPIVFVC
                     NFFGADLVQSLLDVIPQWLMNGLTVMGGILPALGFATTIFTIGKNKFLPMFIIGFFMV
                     QYFEISITAAAIFGVCIALLITFMKEDKRVGEV"
     gene            complement(28655..29143)
                     /locus_tag="KR294_001693"
     CDS             complement(28655..29143)
                     /locus_tag="KR294_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH0239774.1"
                     /translation="MAKITLVRVDHRLIHGQVITKWVKIAQAQKIIIVDDFLGQDEFM
                     ADIYKMAAPSGVEVVILTAEDAGQAFQNNTLGDKNIFILFKNVDMANKAYKAGLKYEK
                     IQLGGIPNEAGKKMVFTAVSLGNEDVEQLNELNENGVEIVLQVIPEESSMTYENALKK
                     FK"
     gene            complement(29161..29562)
                     /locus_tag="KR294_001694"
     CDS             complement(29161..29562)
                     /locus_tag="KR294_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIC"
                     /protein_id="HBH0239775.1"
                     /translation="MNKYKVIILCHGTWGKVLVEETNKNFGLSNQYEVLSLSSEKDVS
                     VFMKEVEEVVDKEDVKIIISDLYGGSTSSVAIAVAIRRGIDAINGLSLQTILIVDEEL
                     SKEDKLHTLPERIVKKNNNLCVDLIKEFKKI"
     gene            complement(29565..30062)
                     /locus_tag="KR294_001695"
     CDS             complement(29565..30062)
                     /locus_tag="KR294_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH0239776.1"
                     /translation="MSLVKYCRCDDRLIHGQVIYKWVKHLGVKKIVVVDDETTNDVIA
                     KGLIKMAAPKNIDLSILTVSESRRYFYNNQADDNVFVLIKNLDTANRMIEEGINIKKL
                     IVGRIPTGIGKKKISQNVYINKKEFLLIDEFIKKNINVSIQMVPDEEEVELNQNINRY
                     KGEFI"
     gene            complement(30086..30490)
                     /locus_tag="KR294_001696"
     CDS             complement(30086..30490)
                     /locus_tag="KR294_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH0239777.1"
                     /translation="MIGIIVMTHGSFSEEIIKSCELIAGPAERTAAIKLNRNDNIEDL
                     NKNFVEKLNELDEGDGVLVLADLLGGSPSNVASLNLKKGGKFHALTGVNLPMLLEALI
                     NREGKSLEELAEACIEAGQTGINNINKVLSSM"
     gene            complement(30720..33287)
                     /locus_tag="KR294_001697"
     CDS             complement(30720..33287)
                     /locus_tag="KR294_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH0239778.1"
                     /translation="MTQKKLSRKEKVLICLKRLTEEHLNFNNGIRFGFDAEYIATEVG
                     INRSNASKELNQLIKESIIIKIKGKPVQYLYKESIESILGKKLNKGIFDNINSINEYS
                     ENDSIKDEYILESIKKENNIFNLVGCDGSLRSQIEQAKAAVIYPPKGLSTLIIGPTGV
                     GKSIFAEYMYKYSLTIKEDSDNAPFIIFNCADYSDNQQLLLAQLFGYVKGAFTGADKD
                     KYGIVHEANNGVLFLDEVHRLSAEGQEMLFLLMDKGIYRRLGEANKVHECRVMIIAAT
                     TEDPETAMLETFLRRIPVTIKIPSLEERGFQERMKLICYFFKEESVRIGVKLKVSKEV
                     IKAFILYKCKGNIGQLKSDIQLICARAFLDYMTYKRECVYVRLSLLPNNIRESLYGNN
                     RKEEFVQNFSFIGKDDIIFLPEEKDFESENLLIENKKYDLDFYGMIKETWNKLQQEGI
                     KESQIRSVIDGDIQKYSYNLMNTFIYNSSNQTAYNNIVNDSIATTVKYILQKHDKWSK
                     REGLDKLIKAIALHIQNLIERIKIGNIVKHPNKDEIMKERAYEYNIAKEILSNMSLMY
                     GVEFPEDEAIFLATFLYLSYVGLNEESIAILVIMHGESTASSMVNVANTLLDCNHAVA
                     INMGLEDRVQDILVQAVEIANKIDKGKGILILTDMGSILTFAKVIRDATGKEVKAIDM
                     VSTPIVIEATRKALTPEMTLEKLYFNIIESIKKHYGDMEVTYAEKDNGGRYFDRLLID
                     NISKTLTFLNGEKAYFILKEVINRISEHYSLVIQDELLVKFIFHCSCMIERVIIKESL
                     VYKSYEERISRNKELYLVIKESFKLVEETFDIIISDMEYANILDIFESQYDTDKFKS"
     gene            33453..34196
                     /locus_tag="KR294_001698"
     CDS             33453..34196
                     /locus_tag="KR294_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase"
                     /protein_id="HBH0239779.1"
                     /translation="MNFLSDLHTHSIVSGHGYSTLLENINYCKENGIKILGTSEHGPK
                     MPGSPHRWYFHNIQNIPRIINNIIILRGCEANILDIKGNIDLEPFVIPRLDYLILSFH
                     EAVFSPNTLENNTKALINAINKHDNIEILGHLGNPNYPIDYELIIKLAIEKNILIEIN
                     NCSIKGVSRNGSSDNCKYIATLCKKYGAKIILTSDAHICFDIGNYEYSENILKEINFP
                     DELIMNYPKKLINHFHQKGKLLDVDYTNI"
BASE COUNT        11337 a         6371 c         3566 g        13630 t
ORIGIN      
        1 cttaaaaata attcgtcaat actttttaaa attatttttt aaaaatattt actttcttat
       61 attacataat ttattgaatg gcagtcatac tgttggttta gagtatttta acacacacat
      121 tttgttgtaa aaattacaac tattaatata atatatatac aatcataagt attataattt
      181 ttatgaatct aatttaaact taatataaac ttattaataa accttctatg tctaaatttt
      241 aaaattacaa tataaaagct ctacactaaa taaatacatt aaataaacat aatggataat
      301 gaatataaat ttatatatgc aaagcgctcc aataaaaagg taccaataaa gttaaaagaa
      361 acttattgat acctttcatt attacatact tcaatatata attataagtt ttttaaatag
      421 tatggattta catttatccc ttatctcata gctctcatag catttactac tgctataagt
      481 gccacaccta catcagcaaa tatagcttcc cacatagtag ctactcctcc agcacctagt
      541 atcataacta taatttttac tcctagagca aatattatgt tttgccacac tatcttatta
      601 gtcttgtttg ctatttcaat tgctttagat atcttgctag gctcatctgt cataagcact
      661 acatctgcag cttcaatagc agcatctgaa cctaagcctc ccatagctat accaacatca
      721 gcacgagcta atactggagc atcatttatt ccatcaccta caaacgctat tttctctttt
      781 tcagttcttc cttcatataa atcttctaat ctatctacct tttcattagg aagtaaattt
      841 gagtaaactg tatccaattc taattcttga gcaatatttt ttgctacttt ctcattatct
      901 ccagttaaca ttacaacttc ttttacccct atttctttta agcttcttat ggcattttta
      961 ctatcttctt ttacttcatc agagataact atataacctc tatatacttt atcaacagca
     1021 atatagacta ctgtgcctac ttctttagct gatgaataag atatattttc ttttttcata
     1081 agtttctcat tacctgctaa tataaaattg ccattatgct ttactctaat tccataagct
     1141 gctatttcct cataactgtc tattgtatct aaatcaattt ttttattata gtaacttaat
     1201 atggactttg ctattggatg atttgaattt acctccgcaa tagctgcata ttctaataat
     1261 tcttcttctg atataccttc aggatttaac ttagttacat tgaacacacc tttagtaagt
     1321 gttcctgttt tatcaaatac tactgtatct acacttctta aagcttctaa atagttactt
     1381 cctttaataa ggataccatt tttagatgca aacccaattc cactaaaaaa actaagtggt
     1441 attgataaaa ctaatgcaca agggcaagaa acgactaaga atatcaatcc tctatataac
     1501 caatcactaa atacctcacc tgagattaca agtggtggca caaatgctat taataaagca
     1561 gctattacta ctattggagt atagtatctt gaaaacttag atataaagtt ttctgtcttt
     1621 gattttttaa tgctagaatt ttcaacaagg tcaagaatct tagaaactgt tgattctcca
     1681 aaactctttg taacttcaat actcaataaa gcatttttat ttataacacc tgataagatt
     1741 tcatctcctt tttcaacttc tctcagcact gactctcctg tgagtgcaga agtatctaac
     1801 atagaaactc catctactac tacaccatct aatggtactt tttcaccagg ttttactact
     1861 attatatcac ctacatttac ctcttctggt gacaccacct taacttcaga attaactttt
     1921 agatttgcat agtctggtct tatttgcata agtgaagtta tagactttct ggatttacca
     1981 actgcaacac cttgtaaata ctctcctact ttatagaaaa gcataacccc tactgcttct
     2041 gataactccc ctattgttaa tgctcctact gttgctagag ccatcaaaaa gttctcatca
     2101 aatactcttc cttttgatat atttcttatt gctcttaaaa gcacatcacc acctactatt
     2161 acataggcaa ctataaatac tatattgcta aactgacttt cataacctgt agctgtttga
     2221 tatataccaa atatatatac aagtgctcca attataagtg gaattaattc tttcttattt
     2281 gtatcattta cagctcctga tttttcagta gttctccctt ttactttgtc agtagaccct
     2341 acttgtatat caagccctgg ctctgttgaa tttattattt cttttatttt atttataaca
     2401 tcatcctctt caaagttatt acttatattt actgtaagtt ttttatttac aaagtttaaa
     2461 ttagaagatt caacttcttt taatttagaa actttgttat taatctcttc tgcacaatga
     2521 gcacagttta atcctcctaa tataagctct tttttaattg atgttttact agctgcattt
     2581 tctttagaac ttatttgtat atcaagacct ggatctgttg aatctattat atctattatc
     2641 ttttctatag tagtatcctc attaaaactt tcctttatat ttactgtaag ttttttattt
     2701 ataaaattta aattggaaga tttaacttct tgtagtttag aaactttatt attaatctcc
     2761 tctgcacagt gagcacaatt taatcctcct agtataaatt cttttttaat tgaattattt
     2821 gcttccatat atattcactc ctctcattta tcatttataa gtctctctaa tatgatttaa
     2881 tccacaatca aatatctgac ttatatgact atcatctaat gagtaataca ctgtttttcc
     2941 ttctcttcta aactttacta atctagcctg ctttaatact ctaagttgat gagatattgc
     3001 agaatgagtc atatttaata aactcgctat atcacataca cacatttcat ttgcaaataa
     3061 tgcatataat atctttactc tagtagtatc cccaaatact ttaaataatt ctgctaaatc
     3121 atataacatt tcttcatctg gcatagttga tttagcctct gttactattt cttcatgtac
     3181 tatattacaa ttacaatcat ttatctcttc tctcattttt aatcctccat tattttaata
     3241 tatgaataac tgttcatatg ttcattatat gttatcattt ctaaatttgc aacaataatt
     3301 tttattaatt taatataaat agaatgcaca tattataaac ttttttaata tatatattat
     3361 tagaataagt ttttgtaaac ttttttatag ttttctagga ggtgcaagtt taatatgagt
     3421 aacaagaaaa aaaaggattt agatactagt tacatgcctt acttagaccc agcgaactat
     3481 gcagattata ttactaatga agaaattccc caagatgaat tgagaaatga ccctcaaatt
     3541 tctaatggtt atacaaaaat acctaataac cagaacataa ataacctata tcctaataat
     3601 gtaaatcatt atcctaaaag tagtaattct ccaaacaact tgcctaacac aaataataca
     3661 tccggaaata tgaattacaa tacatctgct acaaataata tgcctaataa catgaataat
     3721 aatacgggta tgcctaataa tatgtctaac aatatgaata gtaatatggg tatgcctaac
     3781 aatatgccta ataacatgaa tagtaatatg ggtatgccta acaatatgcc taataatatg
     3841 aatagtaaca tgggcatgcc taacaatgtg cctaataaca tgaatagtaa tatgggtatg
     3901 cctaacaata tgtctaataa tatgaatagt aatatgggca tgcctaacaa tatgtctggc
     3961 aatatgaata acaatatgta tggtaataca ggtatgccta ataacatgaa cagtaatatg
     4021 gggtataata tgaacaatac tatgggtatt cctaacttct catgtaatca aaatatgcct
     4081 cctaatgtac ttatgatgat accaggagtt atatgtcata atacaatgca aggtatgcct
     4141 gtagttatgc ctagtactat gcctcctaat atatatccta ctccttatgg ttctagtaat
     4201 atgtctgtac aaggtatacc acaagctact aatattgagg aatttgatga ggaagaaatg
     4261 taatatatat ttttttaagt aagttgtata aaacattaat aattgaccat aataataaat
     4321 gtattcctca taatattccc ccaatattat tataggtata gaaagttgac tgaatatgcg
     4381 cttattcggt caacagatat taacataatc taataagata aacatagaaa aagtcagata
     4441 aaatttaatt ttatctgact ttttcattta aaaatgctct cttgtgttgg tgattcagaa
     4501 tagtatggta ctcgtatttg agactaatat tggcaaacaa cataaagaaa aatataaatt
     4561 ttttataata aactgtataa aattttaata attgaccaca ataataaatg tattcctcat
     4621 aatattcccc caatattata gaaataaatt taagcgagat taaattcagt taatctcgct
     4681 taaataatgt ctaaatttat tattccaaaa aatcatcaaa atctaatgaa cctgattctg
     4741 caaaatcata taatgcattt tgctcaaaga aaaatttctc ttcaaattta atatagtcgc
     4801 tataattaga ttgacttatt tcattgatat aattgcaatc attttcgtta taagtaccaa
     4861 taaaaaactt atttcccatt aagtaatata tagctttcat atcattattt attatatata
     4921 cattttcttt tacatggtca ttattaaaat taaatctagt aaagaatata ccttcattca
     4981 tattactttt taacagaaat ggattttctc tataaaatac tcctgcaaat tcttcaggtg
     5041 aatttacact gtaaacactt acaaattcac ttttagaaat ctcatcaaat acctcaaaat
     5101 catacatagg ttctttatct gtcactaata gagaattaat tctaaaacca gtttcataac
     5161 acttacttat gcaaaaagca attttacata tataatatcc atcattatct tcatataaag
     5221 cttcacttat atatctgcct tgacctttat cacttaccac gtttttaagt aatgttccat
     5281 ttatattagt aatgtgcata tttgcaatct cgtcacttcc agaaaagtac tttaaacttt
     5341 ctctatccca tgctataaat ctcatggtca tatagtttat aaattcaact tcctcgtcaa
     5401 ctcttttaca tattttattg tataattttt ctatagttaa atctgtttta tagtttttta
     5461 taatatcaat atactcacat ttatctcctg gcaatagctt atcataataa agattcttat
     5521 taccaaaata agatactaaa aataaagatt catccttcgt taattcaact ctatctgaac
     5581 caaatcctcc catcaatctt tcttcttcca tataagcttc ttcttgtgtt gggttattta
     5641 aactcacata atccgctaat cctaatccct ctgcatctaa taaaaaatat tgacaaaagt
     5701 gattgttttc atcatctatc caatttatta taagacctaa actgcccata agtctagaat
     5761 ttgtagcctt tgcaaaatta aaattcatat agtcacatcc tttaaactct aaaatacttg
     5821 ttttttaata tataaattat tatacatata ttttaacaac ttagatacaa tttataatat
     5881 aatataagga aatgattaat tgaggtggtc ttatgaaaaa tatagcagct ttttttgata
     5941 tagatggtac tctttataga gactctctta tggttgaaca ttttaaaaaa ttaattaaat
     6001 acgatataat tgaccaaaaa aattggtata aacatgctag agacactttt atggattggg
     6061 ataaaagaca aggtaattat gatgattatc tattagaaat atgtgacctt tatgttgatt
     6121 cactaaaagg attagataaa acctgtatca actttacaag tgaccaagta attaaattaa
     6181 aagcagatag agtttataaa tacacacgtt caaggattga gtggcatcta aatcaaggac
     6241 acatagttat atttatatct ggtagccctg gatttcttgt tgaaaaaatg gcaaaaaaat
     6301 ataatgtaac cgattttcta ggaagtgatt atgtctttga aaacaatata tttacaggca
     6361 cagttattcc aatgtgggat tctataagta agaataatgc tataaacgat tttgttgtaa
     6421 agtatgattt agatttatca aactcgtatg cctatggaga tactaatggt gatataaata
     6481 tgctaaaaag agttggaaat ccaatagcaa taaatccaac aaaggaactt ttatctcaaa
     6541 tatcacttga tgaggaaatt tctaaaaatg ttgagataat agtagaaaga aaagatatta
     6601 tttattctct atctacagat gtaaatatag tggatattta atttatacta tctattttaa
     6661 aaacttatat tatatctaat atttatatct aacatataaa agctttgact aaaaatcaaa
     6721 gcttttatat gttgcactaa gaatatatta aatttagctt tatgctttaa tgtatattca
     6781 tatatatcat ttacacttat ctaaactaca atttcattaa aattaaatat aaaaatcaac
     6841 tattattttt taaatagcat ctttcttaat ctattattgt aataacctat aaaagaactg
     6901 taaacatagt catatactat aaaggctatc tcaaatgaac ctataataaa tatgtttatt
     6961 ggaatataaa ctattgttct taataaaaaa tacaatataa gtatcattat atttgcaaat
     7021 actaatttca taaaatactc aatatatata gacctatctt tttctataag atattttaca
     7081 ataccatata ttccaaaggt aagtgaatat acaatccatt gagacttact tgccatcact
     7141 ataaatccta aaactataga acctatataa aaagcaattc cactcttaaa gccccattcc
     7201 attattacaa ttgatactaa aagtgatgct aaccccataa taaacaatgt atttacagga
     7261 ataatgtttg taagagtcaa caatatcaca tttaatgcta ataaaactcc tccataagca
     7321 acttttatac tcatatttat catcctaaca acaagttatt aaatctccac caaaacattc
     7381 acaacatgaa tctaaacacc aaagtttagc acaattttca caacaatcgt cacctagaca
     7441 acaacagcaa tcatcacagc aacagcaaca acatccatct aaatcattac gtcttcttct
     7501 attataattg tcagccctat tgctataatc atttctatat tgtgtataac ttctaagtgc
     7561 atcactatat tcactatttt caggctccat aaattttgct ctttttaaga agtcttcacc
     7621 ttcttcataa tatcctatgt tcattgcaga aaaaccagtt aaataatacc actctgcaca
     7681 tttgtcagtc aaagttttta aaaaatcata tgctttttta aattcactat tttctatgaa
     7741 tgatcttgct ctcataaaat tttcattatt ataagtatta ctgtacattc tttccacctc
     7801 tactttctaa tatattaata tatcttaaat aaacaccaga ataaattata ttttctatta
     7861 ttccaacatt tttatttaga tttagattat caattcccct agctaaaaat cctaatgatg
     7921 ttactattat tttttttact ttttctttta actcatcatt tttatcaata tactctataa
     7981 atggattata tcttcctttc ttaaaatctt catctaaatc ttcataggca tctagtagat
     8041 atatatactt acctatatta aaacctatca ttcttaagtt tctctcattt tcatcttttt
     8101 tatagacaaa tacttcaccc attatatttc caaatatact agatacttca tctatattta
     8161 tatttttatc tttttctaac ttatttaatt catttagttg ttgttttata tactctgctt
     8221 tttcaggata cttttcatat gctaatttta atttgttttt atatatataa tatgccaatt
     8281 tatcttttat gcgtttatca tccattaaat tatcttccaa tttataatac gttaaaagaa
     8341 tattcatact tgctgcatat tctgtaatat catttgtaat tacctttttc tttttaaatg
     8401 gatttactat acacacttcc tctgtactta tagactctgg gttatatact gctgttaata
     8461 aaacaattaa aaatgttata tcatagttca aagaaaacct agagatttct ccatgatttc
     8521 tttttaagta tttacatagt ccacaatagt aagctttgta ataatcatat tctctaaatg
     8581 ttaaatccat tttgtttatt ttaacatatc caaacataaa tactcctttt tgtactattt
     8641 tttatttaga ttatatatag tataacactt tttatcaaga ttatataatt tacagtattc
     8701 taagaaactt aaaaaattcc ttctaatcat tgtatcttaa atttaaaata attagaaggt
     8761 tgggttaaaa ataatattaa attatatact tatattaact catacaagtt agttatgctt
     8821 atatcaattt aagttttaaa taattggtat atatttaaaa ctacctacag tatccttcaa
     8881 ttcttttttt gctttgttta taaccaattc atcaagcatt acatcattta ttgaacatga
     8941 tatagattta gatgccaata acattgcctt aaatcccata tcagaacctg cactggcaca
     9001 agattgccat gtatgggcag aaataccaat aggccaaact gaacaagaac actgtgctgt
     9061 aggaattatg tagctaacat ctccaatatc taatgataat gatatacagt tattatgagt
     9121 aaatgtatca tccgtaactt catcatgcag attcatctta gtaatatcct tatttccact
     9181 taatacacta gaaacactac ttcttttatc tatagacact gtctcagcta atttatctgc
     9241 aaaatagtag tcatcttcat tatagttttg cacacctact aatttcatat tttgtgatag
     9301 aatatctgtt aatattgtat ttggaatata gtcatatact ccacttataa tgtcatattc
     9361 cataatagta ccagtcatta atgctgctcc ttttgctata tcaacaatcc taccaaatac
     9421 atctcttaca tgctccattt taactcctct tatgtaatac cacacttctg caaaatcagg
     9481 aactatattt ggcatttttc caccattagt agttacatag tgtactctac aattatcaaa
     9541 tatatgttct ctcaaataat tacaacctat attcataagt tctactgcat caagtgcact
     9601 tcttccgtta taaggagctt gtgctgcatg ggcactaatc ccattatatc taaatttcac
     9661 agagtaatta gcaagtgttg gtattcttat tggagtattt atatcaaatg gatgccaact
     9721 aaaagcacaa tcaattccat caaaaaaacc tttttttatc atcaatactt ttccagataa
     9781 atcttcttct gctggacatc catagtattt tatagtccct ttcagctttt ttagtttgat
     9841 taattccttt actgcaatta cagctcctat tgaacctgta ccaagtaagt tatgtccaca
     9901 tccatgacct gcaccaccat ctacaatagg ttctttagta gtggatactt tttgagacaa
     9961 accatctaaa gcatcatatt ctcccaaaac tgctataact ggtctacctt ctccataact
    10021 agccacaaat gctgtatcca taccttctaa tccctctata ctaaaaccat gtttttttaa
    10081 acattctttt tgtaaatttg aagcatagta ttctttatac tgaagttctg gatttttcca
    10141 tatcttatct gatatatctc ttaattctcc ctgtatctca tctatatatt ccatcaaaaa
    10201 ctttttattt aaattatcca tattaattat ataaacctcc ctgtttctaa taacttatcg
    10261 attatcagcc aaaatgacta attttaactg atttaaaaat attttctacc atacaaccat
    10321 tttatacaat aaaacctctt gacttgtaag tttcatttta tcaagtaaga ggttttcaag
    10381 ttttataaaa tttttagcat gttaaccaat caagcatatt aacccataat ttattatagt
    10441 atttccaatc agtaaattct tttggacccc agtgaggtgc acagtcagaa ctaaagatag
    10501 cagattttcc ttttccaaac tcgccaacag ctacaaatgg gtctcctcca atagttgcta
    10561 aaacaggaca attatctcta gctactgttt tgttatatcc taaaaacttt ggccattctg
    10621 ttggtatacc ttttaatact ggatgttcag agtcaataac ttctggaatt attcctgctg
    10681 gtttttcaac tctatcatct ttatctatca ttgttattgg taatacatct ttgatagcag
    10741 tttctccaaa tctagctttt gcatctattc ctgtaaatga catatatcca cctaccatga
    10801 ttaacgcccc accattattt acatactctt tgattagttc aagtctatct ggattactat
    10861 tgcaatctat aaaagtacta ttagataata agaacgtatt agaacctata tcagataata
    10921 ttatacagtc atactcattt aactcttcta atttatacgg aaaactatct gctgctacat
    10981 gtgcaggcat atgaactgtc tcatatcctc cagattctat tgcttctttc aaccacttta
    11041 cagcttcttc ataatgagtt gtaacaaacg tatcaaaccc ttttatatga gttatatttt
    11101 ttacccaaga ttcccctact attaatactt ttttcattta tatattcctc ctacttttat
    11161 aagtttaata ttagacttgc atacataagt atactatcta aatactcctt aatttcaaca
    11221 tattcatcaa ttgaatgaca ttgttctatt gaacctggcc ctaatataag tgttggtatt
    11281 tcagctaaat ttttcattac tctcgcatca ttgccagctg ttgaaccttt tatctctaat
    11341 ttttttccta gagtttcttc tagtatttta tgtgcattca ctacaaaatc agaatccttg
    11401 tccatctcaa aacctaaccc tgattgatat atgtttatat ttggtttatt atctttaagc
    11461 cataaatctc cattagccct tgtcattatg acatttgtta catcatttac aacttgttca
    11521 taactcatta tatttggcaa gaagtgtaca cataaattaa atacacactt atctggcaca
    11581 gtagaacctg ctgttccacc atttattaca cctaaattta ttgtaggtga aggtaatagt
    11641 ggatgtttat atatcataag ccagttatgt tccaactctt ttatatcttg aagcaacaac
    11701 atagccttct caattgcatt tacaccctcc cacttactac cacagtgaag agacacacct
    11761 ttaacctcaa cttcaaagaa tacaaatccc atatgtgcaa ctattaagtt ttgttctgat
    11821 ggttcacaaa ttatgcaaca atctccatca ataccattca taactgcatt tatggtacca
    11881 tttccgccac cttcttcatc tactactgac attattttta cattaccagg tacatttaga
    11941 ccactatctt ttataagctt tacagctaat attgatgcta taagtccaga tttcatatca
    12001 gcagttccaa gaccataaag ttttccatta tcttctgtag cacgatatgg attatatttc
    12061 cacttactta tatcacccgg tggcatagtg tctacatgac cattaaatac aattgtctta
    12121 ccaggtaaat catcactata cttacaaatt aaattatatc tatcttgata attgtgacct
    12181 agatttcctt ctttatatat attttttgct tttttaatta attcttcgct catttcttgt
    12241 ctatccacac taaaacctat gtaatttgca agtttttcaa tatattcctg tccttctttt
    12301 tcaaatccac ctagtattcc atgaccaaca tcttcagtct ttatacttac aagttctttt
    12361 aaataatcta tgtattcttg ttttttacta tttaatgtat ctaagagaat ttttttcata
    12421 tttcctccta agatttattt ttacatttaa aatttcaagt ctaatctcat ctatttaagc
    12481 catagtaaac tttttcactt agcatattct cattcaatgt ataaagatgt atgcaaatta
    12541 aagtataaaa atatatacaa aaacttaata atttttatag tttataagct aaaatttaat
    12601 tactatttag atttagctga tttttttaat tttatattat ttatccatat agcaaataac
    12661 attaccaaac cttttataat catttgatta tatgaagata cacttaataa gtttaatcca
    12721 tttcctaata ttcctattat tccgacacct atacatgtac ctactataga accagaacca
    12781 cccatcatat tagtaccacc aagcacaacg gctgctatag catccaattc tgctccatct
    12841 ccaacagttg gtgaacctga tgccaaacgt gatgatagta ttatcccagc taatgctgtt
    12901 agtagtccag ctagtgcgta tacttttact ataactttat ttacttttac tccacataat
    12961 ctagcggcct cttcatttcc acctactgca tgtacatgac gtccaaaatt agttcttttt
    13021 aatagaaaat gtcctgctat tacaactata atcataatta taactggtat tggtattggt
    13081 ccaatatatc ctctaccgag catcttaaat gcatctgtat ttactgatat aggtcttcct
    13141 cctgtaaata caaagcttgc cccacttatt atcgttaaca tggctaaagt tacaatgaat
    13201 ggaggtagtt tttgtgttga aataattgca ccttttatga ctcctaatat tgtccctatt
    13261 gctaatgcaa gtatcatacc tacccatata ggtgcattat aattcactac tgttgtagcc
    13321 caaaatgtac ctactaaagc aattactgct cctacactta aatctattcc tcctgtaatt
    13381 attacaaatg tcatacctac tgcaagtatt gcatttattg atatttgtct tccaacatta
    13441 attaaattat ctaaagttaa aaagttagat gaagctacac tcattattat aaaaattatt
    13501 acaagtccta cagctgcact cccttggtct ctaaatacac ttgttaattt tgtcaataat
    13561 ggagaagatt tttcttcttt atgcttagtt attgaactca ttaattttac ctccgaaagc
    13621 caattttaat acattatttt caaccatttc ttcaccttct aaaaatccac ttatatgacc
    13681 ttctctcata accattattc tgtcactcat tgatattaat tctggtattt cagaagatat
    13741 cattattata cttacaccac tctccactaa atctcccatt agattgtata tctctgcctt
    13801 agcatttaca tctatacctc tggttggttc atccataatc aatatatctg gttgtaataa
    13861 aagccatctt gctattatag ctttttgttg gtttccacca cttaaacttt gtataacttg
    13921 attcatatgt ggtgttttta tctttaaagc ttctatgtat ttttctaaaa tctctttttc
    13981 cttttttcta tctataattg atttaaactt agatatcttt tttaacccag ccatagttgt
    14041 attttctttg acactcattt gtaaaaacaa tccagtacct tttctatctt ctgttattaa
    14101 tcctagtcca ttttctattg catctgatgg agttttaaac tttacttctt cattgtttaa
    14161 atatattttt ccagaatcat atgttctaag tccaaatata gcttctacta tttcacttct
    14221 cttacttcca actagtccac ctattcccaa tatttcacct tttcttatat taaagctaat
    14281 atcattaaaa acattgttct tagttagatt ttccactcgc ataatttctt cttttatttc
    14341 tacttttctt tttgggaaaa attggtctag ctttctatct atcattaaat taactaattc
    14401 ttcctcagac gatacatctt tggtatttaa agtcgaaatc gttttcccat ctcgcattat
    14461 agttattctg tcacaaatct caaagagttc ttccatccta tgggatatat atattatact
    14521 aactccactc tcttttaaat catttataag tctaaaaagt atttcagtct cttttttact
    14581 tattgaagaa gtaggttcat ccattattaa tactttagtt tctgatgata aaactcttgc
    14641 tatttctacc atttgttttt gagctatact aagctctttg actaaactat ttggatttat
    14701 atctattccc atattatcga aaatcttttt agcctcttca ttcatttttt tgtcattggt
    14761 taagactttg ccatttattt cttttcccat aaaaatattt tgtgctactg ttaattcgtc
    14821 aaaaactgtt agttcttgat atatggcatt tatacctatc tttttagaga tatctgggga
    14881 tatattctct atttctttgc cttcaaaaat aaattttcca gaagttttcg aatgtgcacc
    14941 agttaaaatc tttatcattg ttgatttacc agcaccattt tcacccagta gtgcatgaac
    15001 ttcgccatga aataactcaa aattaacatt atctaatgct ctgacaccag gaaattcttt
    15061 agcaatatta cttaacttca gaattatatt actcataatg acactccttt ttaaatagga
    15121 tttctttcaa ataatctcat tttattttac taattcttaa agtcttttat attttcctta
    15181 tcataaagta aagctggtac tggtatattc ttttctacct tttccccttt tatagctttt
    15241 actactgctt ctacagctaa acgtcccatc tctttaggtt gttgttgaat catagcaaga
    15301 atagttccat ctgttattcc acttgatgct tcttcagtta agtcaaatcc tacaatctta
    15361 acatccttat tttttgcaga ttcaagtgca gctttagctc ctagtacact attttcagct
    15421 gttgcatata ttatatctac atctggatta gattgaatta agttttctac tgtattaaga
    15481 gattcttctc tgtcatatcc tggttgtgaa tttaatatct taacatttgc tgaacctttt
    15541 aatgcatctt taaatccatc tattctctgc atttgtattt gagattttaa atctgtcact
    15601 attgctattt ctgactttcc acctaacttt tcatctatgt attttttagt gtattcccct
    15661 aattttttac cagcatcata actaactgtt cctacataac ttgtaatatt ttcagtattt
    15721 aatacagcat ctactgtaac tactggcatt ttttcaaatg ctccttctac tgctggtact
    15781 atagccgaat tatcagttcc aagtactatc attccatcta cattttgttg tataaaatct
    15841 tctattgctg atgtttgctt agctacatct tggtctgggt catttactat aactttcaca
    15901 cctaattctt tagctttttc ttttattccc tcatcaatat ctataaaaaa ttgatgttga
    15961 agagttattg tagatactcc aatagttaaa tctttcttgt ctgaaccacc tttattatct
    16021 gatttacttg gtccttccat tgaacaccct gttaacattc ctattgctag tattccagca
    16081 attcctaaag ataaaatttt tctcactctc ataattaacc tccattttta atagttttaa
    16141 atttgaacaa attagatttt tatttattat ttaaatattt ttcaacatct tctttataag
    16201 gcataccaga ttgtgcacct agtttagtta cagacagacc tgatactact actgcatatt
    16261 ctactgctgt atataaattt ttcccttctg ttatagccac tgccaatgct ccattaaatg
    16321 tatctcctgc tcctgtggta tcttgaacat caacacttat acaagataca tgcttgattt
    16381 cctcaccatc ataaaatcta gctccatttt ttccttctgt tattacaagt ttatttggat
    16441 atttttttaa tacttcttct atcccttcat ttgtgtcaaa aactatctta tattcatgtt
    16501 catttggtgt taagtaagtt actttttcta ttatatcttc atttagtttt actgctggtg
    16561 ctggatttaa taaaacccta atcctatttt caaaacagaa attcactaca taatttattg
    16621 tttttaatgg aatctctaat tgtagcaata ctatatctgc attctttatc tcttcttcat
    16681 tctttttaat taattctata tctactagct cattagtccc tggtacaaca acaatactat
    16741 tatcattttc acataatgtt ataacagcaa caccagaact tttgtgatta tttctggata
    16801 ctaagctata atcaacttta ttcgttctaa aatttcttat taactcctct cctaagccat
    16861 cttcccctat gcatgatatc atttttacat ttgctcctag tttagaagct gagatagctt
    16921 gattagcccc ttttcctcca ggtgatgtaa aaaaactatt acctaatact gtttctcctt
    16981 tttctggtct tttatctaca gaacatacca tgtccatgtt tacacttcct atgacaacta
    17041 tgtttcccat tacattactc ctttacatat ctatttatgt ctctcgtgct gttattcact
    17101 ttcttttgtt gaatctctta tgaccaattc tggtttgaaa atcaattcat caaacgattc
    17161 ttttttatct cctcttaaac aatttatcaa tatttcactg gctttatatc ctatatcata
    17221 agacggctgt tttactgtgg taagagaagg gcttattaga cttgatgttt gaatatcatc
    17281 aaatcccacg acacttatat catttggtat acttaatcct ctttctttaa gacctcttat
    17341 gacacctatt gcaatcaaat catttgcaca aaatattgca tcaaaatcta tcttttctaa
    17401 attttttata aattcttgtc cccattcaat cttatatttt ccttcaaata cataagcagg
    17461 attgtagctt aaattgcact cgattagagc ctttttatat ccttctaatc tatctactgc
    17521 tatttcattt tgaagtggac cacttaggta tattattttc ttatttccaa tatctaataa
    17581 atgttttgta gctatatagg ccccttcaaa gttatttatt ttaacaattc cttttaaggt
    17641 ttctttgttc atacttatct tcttatcaat caagacagtt ggtattttta tatctttata
    17701 atttgcttct ttccagtttg tatttgaaga tgctgcaaat ataattccat ctatcatcct
    17761 ctctgatagt gttcttattc cttcatattc ttttttagca tcttcatctg tattacataa
    17821 aattatattg tagccttctt cattagcttt gtcttctaca cctcttgata catctgtaaa
    17881 gaatggattt cgtatatctg gtataagaag ccctatagta ttagtttttt tagttactaa
    17941 actttgtgct aatttatttg gtacataatt tttttccttc attattttca aaattttttc
    18001 tcttgttgcc tgacttatat tttcatcttt attattaatg acttttgaca cagttgtttt
    18061 agaaacacca gccaattcgc caatttcttt tatagttata ctcaagaagt tcacccccaa
    18121 aatttaggaa accgttttac ttaaccggtt acctagatac tatcacatct tttttccatt
    18181 tgcaaccatt ttatataaat tttgatattt ttcccttttt tcaaaatatt gcaacttata
    18241 attcaatttt aatatttaaa ttaatctgaa aaaaaaatta atatactttt ataattatct
    18301 aaaagtatat taattaattt aagcagtatt tattaaagtt caaatccttg ctctataatc
    18361 atttttttat cattttcaat cccacttcca acagttgtca aataatcacc aacaattgca
    18421 gaatttactc ccccattaaa tccaactttg tcatatccct ttaatgatag ccttccacca
    18481 gcatacctta tgtacacatt aggaattata aacctaaata ctgctgttgt ttttagtatt
    18541 tccattggtt ctaatacatc ataattttcc attggtgtat tcttaatagg atttaaaatg
    18601 tttattggaa atgattttac atttaattct cgtatttcaa aagccatttt tagtctctgt
    18661 tcttcactct cattcattcc aattataccg cctacacata catctagccc agctttttta
    18721 gcatctttta tagtttttat cctatcttta tatgtgtgtg ttgtacatat attatgaaaa
    18781 ttatctctac acgtctcaac attgtggtga tatgtagtca cacctgctga cttcaacatt
    18841 ttagcttgct cataatctat aatacctaaa gatgcacata attttaaatt agtattttcc
    18901 ctcaatcctt catagatatt taaaatatta ttaaactcct ttcctgacat acctttacca
    18961 cttgtaacca atgagaatct atgcactcct ttactctcca tctctttagc tctatttaag
    19021 atttcattgt aatctaataa tgaatattct tctacaccag ttttataata agaagactga
    19081 gcacaaaatt tacagtcttc actacatttg ccagatttag cattcattat cgtacataaa
    19141 tctgcttttc ttcccataaa atattctctt atttcatttg cagattttaa tagaatatca
    19201 aaatcgtttt tattatttgt atcaaggctt attaaattaa gagcttcttc ataacttatt
    19261 tctttttctc tcaatacttt attttttaat tttattatgt atttttccat atatcctcct
    19321 atttgtcaac ttaatatttt tatgtagttt acttattata tatagtattg catatataac
    19381 atttattggt caactttatt ttagacacaa gtttactata cacaaaaaaa tactgcttca
    19441 aaacaatatt agtatataga ttatacatat tattattaaa gcagtatttt ttattagaat
    19501 ataattctta ctggtttata aaactatcct tgtcttaact ccatccaagc tttccattgt
    19561 aataacttct aagccttcat attctctaaa tagccatttt aaatccttca tggcttgatt
    19621 aacctgactt tttgttagat tatttataaa atattctttt ctagtttcct catactcttt
    19681 gctagtcaaa aagtttctta gaaaattaaa cgcaaataca cttggaatat tgtttacatt
    19741 agccttcttg ctgttttcct tctcatagta aattttcata aatgcatact cctttgatac
    19801 ttttagattt ctcttacaat aattatatgc atttaagtgc tactattctt ataattttat
    19861 taattcatat tctttacttc ccatacccat ttcacatgca tagtctatta ttctagttcc
    19921 atttacatga ggatgttcat gtttgaaaac atcatgaccc atttccttac aaatcaaatc
    19981 atagcatgct tgttcaatag ctacagggtc tgttgatgct aatattccta tatcatgggc
    20041 aattggtcta cctgaccaag gtacacaatc acaaagtgga gttacattca taacaaaagt
    20101 tatataccct accttgtctt ttttatttga tactgctcca taagcgtatt ctgccatctt
    20161 ttcgacaaac acatctgagt cactttccca ttgtatagtt actgctctag ttggacagac
    20221 agttggacat tctccacatc cataacatac atcagaatct ataactgctt ttttatccac
    20281 tatacttata gcttttgtag gacaagaatt aacacacttt ccacaaccta cacacttctt
    20341 ttcctttact actggagtaa catcagaatg ttgcatttgt tttcctgctg cacttgcaca
    20401 tcccatagct aagtttttta atgctcctcc aaaacctgct gcttcatgac ctttaaaatg
    20461 actcattact atcattgcag aagaattata aatttctcca cctattttta cactttcaaa
    20521 atgttttttg tctattttta cattctcata atttctacta tataatccat ctgcaattat
    20581 tactggtgca tttacaactg cataagcaaa tccattttct atagcagttg taagatggtc
    20641 tacagaattt gttctactcc ctgtatacag tgtatttgta tctgttaaaa atggctttcc
    20701 ttcgcagtct ttaaccttat caaccacttg tctaactgcc acaggactca tatatgtagt
    20761 atttcccttt tctccaaagt gaagtttaat tgcgacttgg tcattttttt ctattaaatc
    20821 tttgaatcct gcttcatcaa ataatcttct tacattgttt ggtacgtttt tattttgcga
    20881 atttgagtat aaatcacaaa aatatacttt tgacttttcc atatctacac ccctttaaaa
    20941 tatttactta tactaatttt atcactttta aagtaatttt tagtatattt taacataatt
    21001 aaatattctt atatttattt gatacaaata atattatttg tattattttc tacacttaat
    21061 tctatatatt aaactacacc taaaaatcaa aaagacttga aacttaagtc caagtctttt
    21121 tgatttttag gtgtagtttt taacaacata agattacttt accttgtgat aaaggtatta
    21181 ttaaactggt tttttattaa ataaaataac agctgctagt aaacatacta tagaaataag
    21241 aactgttata ataattggaa taataaattc tggcattgcc actttccctg aaatcaagtc
    21301 tatatttttt gacatcaaga aattaggagt ataaggtgca atctgtttag gaatagaaat
    21361 taaactcaat aagagagttg ctaccaatac aagtaaaaca ctggcaaatg ctggtctaaa
    21421 tagtacacac ccaagaatta atacactaat atacataatt cctataagcc ataaattaaa
    21481 tgctgaaaat ataatatgat taagatttgc agttggccaa aaatacattg tatagccata
    21541 agcaaataaa aaactcaacc aaaaaccaat tgtcataata atcaccgtaa cagagaattt
    21601 agacaatact atagatgaac gtgataaacc tttagtcagc ataataacaa gtgtcccttt
    21661 agaatattca tttgataaaa tattacaaaa aataattaga gttaaactca taccaagacc
    21721 agagatattg ctaaaaaatt gtgtccaaga atctaaagca gttggtgcag cagtaacttt
    21781 taaagtcggt gcaaaatgag caatcaagtc tggcataaat tttgcagaaa taggactact
    21841 tataccaaat attagaaata aaataattaa actaaataat ttataatttc ttaaattctc
    21901 tttaaattct ttttttgtaa atgctatgta ttctctcact ttactacctc caaaaataaa
    21961 ttttcaagtg ataattctat tagttccatc tttactggac aaagattcat ttctgcgagc
    22021 gtagatataa ctgttttttg tattgctttt atatctttac catgcaaaac aatttccata
    22081 ttagtttctt ctgaatcttt tagtaaggat ttaataccat cactagactt aaacttttga
    22141 atttcatcat tacttgcaaa ctccagtaaa agtctatcct ttccgtgcat actttttatt
    22201 tctgaaagtg taccactaag ggcaatgctt cctttgttta atatagcaac atggtcacag
    22261 attctttcaa catctgatag tatatgtgtt gaaaatatta cagttgttga gtctttgatt
    22321 ttaagcataa tatctaatat ttcttttcga ccaacagggt caagtgcact tgttggttca
    22381 tcacaaataa gtaatttggg gcgtgaaagc aaagcttgag ctataccaag tcgttgcttc
    22441 attccacgag aaaacccacc tattcgtctc ttttcatttc taagacccac aagtgataac
    22501 aactcttcac tccttatctg tatttctttt tttgaaagtc ccgtaatttc accacaaaga
    22561 gaaagatatt caagtggtct catataattg taaaactctg gaacatcagg cagataacct
    22621 acatgacgat tagaacttgt tttcccatag gtcactttct caccacaaac atctatagtt
    22681 ccactatctg gtttaagtaa cccaagtacc attttcattg ttgtagtctt acctgcacca
    22741 ttcttaccta caaacccaaa gactgaccct tctggtacag taaaatttaa attatctatt
    22801 atctttcgat taccaaaacc ttttgataat ccatttattg agacaatatt catcattctt
    22861 cacctcttcc tattgtaaaa tacaaaattg gtcctattaa actaataaac agtactacaa
    22921 taatccatat tgccttattt ccaattttat aatttggatg tctcaacaca tgaacaagtg
    22981 cagtaattat aagtattaaa tctaaaataa taacaggaac caaaagtggt aagtattcca
    23041 tcaaattttc cataatctta ttcctccaat aaagataatt tttctataag aaatttgtat
    23101 tctttgtttt cacttaatac agaaaacatt ggattatttt taatagcagc aacaatacct
    23161 gcttttacga ttgtatcatc acgtgtaata cctgttccaa tttcagaaat ccatctgtca
    23221 agtttattaa aaaagtcatc cccatgtatt ataattgggt atatatcacg tgttgctaaa
    23281 tctacatatt ttcgtaatga tttaatagct ccttcattat caccatgtat taaattaatt
    23341 tgtgcctgtg ttaaatatga agaaagcata atagcaggag ataatgtatc aagctcaaat
    23401 atatctgaaa ttgctagaat acgtctttct atttccttca tttgtaattt atctgcattt
    23461 tgcaaaatac ccactagatt ttggactaat gatataaggt tctgatatgc accaagttga
    23521 aatgtttctc ttgcttcatc catttgacca ttcatcattt gcccttgtgc aagaagtata
    23581 gattcattta tcatgggaaa attgctgttt tgcaataaat caatcacttg tatgggttga
    23641 tttaacaata tataacaagt tgcctccata ctttttgctt gacggcaaat atctatgtca
    23701 ttacaagttt cctgtatacg aataaatatt tctaatgctt cactaattaa tagttcacgc
    23761 tttttttcat ctacaatatc atagtgatta actattaaaa gacccatccg aaaaatcaaa
    23821 ggaaaacatg aataatattt ttttatgatt tctcttattt catccatgac ttcatcaaat
    23881 ggtttaaccg taaagtcttt gcacagttta ttatacagtt tattaatatc ttccttcatc
    23941 atttgaggtt cataacatat taactcatca acggtaatgt tgaaatatgt cgcgagttgc
    24001 ggtaaaaagg ttatgtcagg atagctttgt ccagtttccc atttagatac agaagcttta
    24061 gaaacgccta tataatttgc aagttcatct tgtgtaattc ctttttcttt acgctttaaa
    24121 atcagcgttt ttgcgatgtt taattcattc atgtcaatcc ctccttatgt ataattatat
    24181 ccttaaacat gtaaagctaa caagcgattt gaagttgact tttgacgaaa aaatcaacca
    24241 cagagaaaca aataaacaag tatataaaat atatatttaa atttatcttt aatctccttt
    24301 gtaaaatatg taaactttgt aaataaaatc catattatat aaaactaata gttaatctat
    24361 ctaaatacag tttttattta tcacgttttt aaatattttg tgtaaaacct cttttaatat
    24421 aaacacctta ttttcatttc tcatttcata ttctttttaa aatactgaat ataactcttc
    24481 gattttccat ttaatccttt tataaagtta ttattcgtat ttattcctct aattataaca
    24541 ggcaactatc atgtattggt atttgtctat tatataaaaa tctataaaag aaaagcagtc
    24601 aatcatttag attaactgct tgtacatata tcttattaaa ctgtataaac tataattttt
    24661 attattctcc attttcatcc caagtcataa atccccatcc actatctgga taaatatcga
    24721 tagacttttc tctaatcata taaccaactt tataacactc ttttgttatt ttattagata
    24781 gtatacatcc ttctccattt atctaattcc atttaattaa cttttctttt caaccttaac
    24841 ttttataaaa tcatcttttt taataatttc atacttattt tctcttcaac atcatcaaat
    24901 gagggtgtct caaaattaac tttttacttc ataaggcact cttttttgta tgaagtaaaa
    24961 tatattttca tcatttcaac aataagtaag aggcttatct ctattttgag acagccccat
    25021 ttgatggtgt tgaacattta aataaggttg aactcgtttt atctctcttt ttaagatatc
    25081 tgtaaatttg cacataaagt ctcttcttct tttacaattc taatagtttt attaaagcca
    25141 aagtatatat ctccatattc tttcgtatat gatttattgg tactctttca tctactccat
    25201 gaccaccagt tttatacgct aagaacttag gtccaaacgc caccatatct ttaaaccaac
    25261 ttgcatatgt gccaccaccc atagcaattg tatatccatt ttcatctgtt acttcttcat
    25321 aggcttctaa taatttttta agtactaaat tactctcatc cacataatgt aagtctttat
    25381 gaacaataac ctctattttc caaccattac aaaaaacctt tttgaatcta tctattatat
    25441 tgtttaaaac tatattttta ccatacctta tatctaactc acatacgatt ttttcctcat
    25501 ttacttttaa tattcctaaa tttaaggtag tgtttttgaa tacctcatca tattgattaa
    25561 tccccaatgc atctccataa taatcactac aaaggtattt tgaaactaat tctatatctt
    25621 ctctatgctg aaaatccata ttatcctcaa ctatctttat taccatttta gatatagcat
    25681 tttctccctt ttcaggatta cttgcatgta cagctactcc tttagtagtt aactctgaaa
    25741 taattccatt aataattttt gcagtacaat gagatggaac aacattttct ttagttcctc
    25801 cacttactat tatgtaaggt ttacttttgt caattttaat ttctttttct atccttatat
    25861 gaacccttcc tttttctcca ttaaccactg gatacatagc atctggagta aatcccatac
    25921 ttggaatttc ttcaccttta tctaagtaat atttgataca tttcatacct gtctcctcat
    25981 ttgtaccaaa aattaatctt attcttttat taattgtagg atacatatcc tctatgtttt
    26041 tcaatacatg tataagcata gatacagcac ccttattatc tatgacacct cttccataaa
    26101 taatattgtc aattactgct cccgaaaatg ggtctacact ccacccctct cctggtggaa
    26161 ctatatctaa atgcattgga atccctatta attcctctcc ctctccaatt tctgcatatc
    26221 caatataatt atcaatattt ttaacactaa aacctaaact agcacagtaa tctaaagttt
    26281 tatctaaaga ttttttaggt cctataccaa aaggacattg tgaaataggt tcaccttgtt
    26341 gtgaatcaat ttttatcaat tcttttagaa attctatggt tctatttaaa ctattatcta
    26401 cacttctgct tatatccata aatcaaccta ctttctatct ttttaaagcc tgtccttaaa
    26461 gaacaggctt ttagcattaa aaattatttt tttgtaaata ctaattcaca aacttcatca
    26521 tcatgagcac atttttgagc aaaatctaat ttaacacctt gtgcacagtc aactcttcca
    26581 taatccccat aacaagctaa tctacaaatt tcttttcttt cttctttagt taatccatat
    26641 tctttccaag cagcatctaa tggacagtga tggaatttta aaacgccatt ctcatctgta
    26701 ttttctacta attccatttc aaacactttt tgtcctttac tgttatataa catttctgcc
    26761 atttttcctg gagtatctgc tacgttatat ttttgacctc tcattttacc aaatccatat
    26821 attgcttctt tacatatatc atctggatta gctcctaatt tttcagcttc tttcataaga
    26881 agatagaacc atactgctct ttctcctgtt gctcctctaa ttccttctaa atattccttt
    26941 tctgtataca ttttttctga catttctttc tcctcctaaa attaaattct atattttaat
    27001 cactgtgaat tagaatattc caatgaatga ccctaccaat gctaatacaa ccaaaattac
    27061 taataactta gttattgtcc acttcttgta tttcattccc caatatacga agaatacaac
    27121 accaagtggt aataaacctg gagcaatcat atttaatgta tcttgaacaa caattgcttt
    27181 accaccaata tcaaatgata gcggagttga aagcttaact gtagttgcag ataatgctcc
    27241 catcataaac attcctagaa ttgaagcacc atcaattatc ttattgacaa taccacctga
    27301 tagaattttc ttaattgaat ctctacctaa agaatatcct aaatgaaata agtaataacc
    27361 ttcgcaaaat agtaatatac taaacattat tgggaaaaat gcacctataa cacttccttc
    27421 tgctccaaat gaagcaccta aagctaagaa tattgtttga aatgtaccaa aatctaaagt
    27481 atctccaatt ccagccaaag gtcccataag accattctta acacctgaaa taacttctcc
    27541 tgggattttt ccttcagtag ctttctcttc ttccatagct aaaactgtac cgtgaattaa
    27601 tcctccccat atagcttgag tattaaaaaa ttgtaagtgt ctctttaacg catctactaa
    27661 atcttctttt ctcttatata acttttctaa agcaggagtg aaacttgcac aaactgctaa
    27721 tgcttgcatt ctttcaaaag agttggataa ttctgctgtc caccaccatc ttagatatgt
    27781 ttttgttaca tctttctttg taagtactct tgtcttatta acttcagttg gaccttgtcc
    27841 atttttaact tctttatttt ttatttcttg cattatactt cacctaccct tttgtcttct
    27901 ttcataaagg taattaaaag agctatacaa acaccaaata ttgcagctgc agtaattgat
    27961 atttcaaaat attgaaccat aaaaaatcct ataataaaca ttggtaagaa tttattttta
    28021 cctatagtaa atattgttgt tgcaaaacct aatgcaggta atataccgcc cattactgtt
    28081 aatccattca ttaaccattg tggtataaca tctaataatg attgaactaa atctgctcca
    28141 aaaaagttac atacaaaaac tattggaaac cttaaaacaa acccaaatat taaagaataa
    28201 agtgttgcac atctccagat gccttttgta ttaccttctt cagcatactt atctgcctta
    28261 tgaaccaata cagcattacc agttcttctt aagttattaa ctaatactcc tataacacct
    28321 aaaggtaccg caatagatac tgcaacttct gcattaacac cagtttgaag tgctactggt
    28381 attgcaataa gagcagctag acatttatct gatggaatat ttccccctgc tgcgaccatt
    28441 cctagataaa ccatttctat acttgcacca acaatcatac cagttgttac atcaccccaa
    28501 agtaatccaa ggctaaaacc tataaataaa ggagacttta gtgttgagaa aagggtatac
    28561 cctgcaagac ctgctgcaaa ccaataccat aatcctgtta caattgccaa catcaaaaca
    28621 gattccattt ataattcctc ctaatttata ttttttattt aaatttcttt aacgcatttt
    28681 catatgtcat agatgattcc tctggtataa cttgtaggac tatttcaacc ccattttcat
    28741 taagttcatt aagttgttct acatcctcat ttcctaatga aacagctgta aacaccattt
    28801 tctttcctgc ttcatttgga atacctccta attgaatctt ttcatattta agtccagctt
    28861 tataagcctt atttgccata tcaacatttt taaatagaat aaatatattt ttatctccta
    28921 aagtgttgtt ttggaatgct tgtcccgcat cttctgctgt taaaataact acttctactc
    28981 ctgatggtgc tgccatttta tatatgtcag ccataaattc atcttgacct aagaagtcat
    29041 caactattat tattttttga gcttgagcga tttttaccca ttttgttata acttgcccat
    29101 gaattaatct gtggtctact cttactaatg ttatttttgc cattatattc acctcataat
    29161 ttatattttt ttaaattctt taattaaatc cacacaaagg ttattatttt ttttgacgat
    29221 tctttctggt aatgtatgta atttatcttc tttgcttaat tcttcatcta cgattaaaat
    29281 tgtctgtaag ctaagtccat ttattgcatc tattcctctt cttatagcaa cagctattgc
    29341 aacacttgat gtagatcctc catataaatc tgatattata attttcacat cttctttatc
    29401 tactacttct tcaacctctt tcataaatac agaaacatct ttttcagaac ttagtgataa
    29461 aacttcatat tgatttgaca atccaaagtt tttatttgtt tcttctacta agacttttcc
    29521 ccaagttcca tggcacagta tgattacctt atatttattc attgctaaat aaactctcct
    29581 ttatagcgat taatattttg gtttaattct acttcttctt catcaggtac catttgaatt
    29641 gatacattaa tattcttttt aataaattca tctattaaaa gaaactcttt tttattaatg
    29701 tatacatttt gagatatttt cttttttcct attcctgtag gtattcttcc aacaataagt
    29761 tttttgatat taatcccttc ttctatcatt ctatttgcag tatctaaatt tttaattaat
    29821 acaaaaacgt tatcatcagc ttgattatta taaaaatatc tccttgattc acttacagtt
    29881 aatattgata aatcaatatt ctttggtgct gccattttta tcaaaccttt agcaataaca
    29941 tcattggttg tttcatcatc tactactact atctttttta cacctagatg cttaacccat
    30001 ttatatataa cttgaccatg tattaatcta tcatcacatc tgcaatattt tactaaagac
    30061 atttttaatc aaactccttt ttctattaca ttgagctaag aactttatta atattgttta
    30121 taccagtttg tcctgcttca atacatgctt ctgctaactc ttctaaactt tttccctctc
    30181 tattaattaa agcttcaagt agcattggaa gatttactcc agtaagtgca tgaaacttgc
    30241 cacctttttt aaggtttaaa cttgcaacat tacttggcga acctcctaat aggtcagcta
    30301 atactaaaac tccgtcacct tcatctaatt catttaactt ttctacaaaa tttttattta
    30361 agtcttcaat attatcattc ctatttagtt taattgctgc tgttctttct gctggtcctg
    30421 caataagttc acagcttttt ataatttctt cactaaaact cccatgagtc ataactatta
    30481 ttcctatcac caatttcacc tcacttttct tgtcactttt tatataagca attgccgtgc
    30541 caacttatgt gtatcaataa caaatggcta ttttacagga tttaatcaaa actttttact
    30601 caattttttt taaaaactta ttatttcgat atgtatcaaa agattttttc aacctgtatc
    30661 aaatctgtat caaaaaaagt aaaaaaaaga tagccttttg gctattttta aattttgtat
    30721 caacttttga atttatctgt atcatattgt gattcaaata tatctaatat atttgcatat
    30781 tccatatctg aaataattat atcgaatgtc tcttctacta gcttaaaact ttcttttata
    30841 actaaatata attctttatt tctactaatt ctttcttcat atgatttata aactaaagac
    30901 tcttttatta ttactctttc aatcatacat gaacaatgaa atataaactt tactaaaagt
    30961 tcatcttgaa ttactaaaga atagtgttca ctaattctat taattacttc ttttaatata
    31021 aaataagcct tttccccatt taaaaaagtc aaagttttac taatattatc aattagtaat
    31081 ctatcaaaat atctaccacc attatctttt tcagcatatg taacttccat atctccataa
    31141 tgtttcttta tagattctat aatattaaaa tataatttct ctaatgtcat ttctggagtt
    31201 agagcctttc tagttgcttc tattacaata ggtgtactta ccatatctat tgcttttact
    31261 tcttttcctg tagcatcacg aataacttta gcaaatgtta aaatagaccc catatcagtt
    31321 aaaattaaaa ttccctttcc tttatcaatt ttattggcta tttctacagc ttgtactaaa
    31381 atatcctgaa ctctatcttc taatcccata ttaattgcca ctgcatggtt acaatccagt
    31441 aaagtattgg ctacattcac catgctagat gctgtagatt caccatgcat tatgactaat
    31501 attgctatac tctcctcatt taatcccaca tacgataaat aaagaaatgt tgctaaaaaa
    31561 attgcttcat cttctggaaa ctctactcca tacattaatg acatgttaga taatatttct
    31621 tttgctatgt tatattcata tgctctttcc ttcataattt catctttatt aggatgcttt
    31681 actatatttc caatctttat tctttcaatt aaattctgaa tatgtaaagc tatagctttt
    31741 attaatttat ctaatccttc tcttttgctc catttatcat gcttttgtaa aatatatttt
    31801 acagtagttg caattgaatc attaacaatg ttgttataag ctgtttgatt actactatta
    31861 tatataaaag tattcattaa attataggaa tacttctgta tgtctccatc tataacactt
    31921 ctaatttgtg actctttaat accttcttgt tgaagtttat tccaagtttc ttttatcatt
    31981 ccataaaaat ctaaatcata ttttttattt tctattaata aattttcact ttcaaaatcc
    32041 ttttcttctg gtaaaaaaat aatatcatct tttccaataa aactgaaatt ttgtacaaac
    32101 tcctcttttc tattatttcc atataatgat tctctaatat tatttggtag aagagagagc
    32161 cttacatata cacattccct tttataggtc atataatcta aaaaagctct tgcacaaatt
    32221 aattgtatat cgctttttaa ttggcctatg tttcccttac acttatataa aataaatgcc
    32281 ttaataactt cttttgaaac ctttaactta acaccaatcc taacactctc ttctttaaaa
    32341 aaataacata taagcttcat tctctcttga aagcctcttt cctctaaaga cggaatcttt
    32401 atagttacag gtattcttct taaaaacgtt tccaacattg ctgtttctgg gtcttctgta
    32461 gtggctgcaa ttatcataac tctacactcg tgtaccttat tagcctctcc taaccttcta
    32521 tatatccctt tatccataag cagaaatagc atttcttgtc cctctgcaga taatctatga
    32581 acttcatcta aaaacaatac tccattatta gcttcatgta caataccata cttatcttta
    32641 tcagctccag taaatgctcc ttttacatat ccaaaaagct gcgctaataa taattgctga
    32701 ttatcagaat aatcagcaca gttaaatatg ataaatggtg cattatcact atcttctttt
    32761 atagttaaac tatacttata catatattct gcaaatatag atttaccaac tcctgtaggt
    32821 cctattatta atgtactcaa ccccttaggt ggatatatta ctgctgcttt agcctgttct
    32881 atttgggacc ttaaacttcc atcacatcct actaaattaa aaatattgtt ctcttttttt
    32941 atactctcta aaatatactc atctttgata gaatcatttt cactatattc gtttatagag
    33001 ttaatattat caaatatccc tttatttagt ttctttccta aaatactctc aatactttct
    33061 ttatataagt actgaacagg cttacccttt atctttataa taatactttc ttttattaat
    33121 tgatttaatt ccttactagc attacttcta tttataccta cttcagtagc tatatattct
    33181 gcatcaaatc caaatctaat gccattatta aagttcaagt gttcttctgt taaccttttc
    33241 aagcaaatta aaactttttc tttccttgat agcttctttt gtgtcatagt taacctcccc
    33301 tataagcagt aatactgtta aacatttatt attaagctta attctacaat attttaatat
    33361 ttttgtctaa ttatgtaact attgattttc tttcctattc gttttataat ataaattacg
    33421 ttaccctcat cttttataga ggaggaattt atatgaattt tttatcagat ttacacaccc
    33481 actctatagt cagtggtcat ggctatagca ctttactaga aaatattaat tattgtaaag
    33541 aaaatggaat taagatacta ggtacatctg aacatggtcc taagatgcct ggttctcccc
    33601 acagatggta ctttcacaac attcaaaata tcccaagaat cataaataac attataattt
    33661 taagaggctg tgaagcaaat atactagata ttaaaggaaa catagaccta gagccttttg
    33721 taattcctcg cttagattat cttattttgt catttcacga agctgtgttt tctccaaata
    33781 cattagagaa taatactaaa gctttaataa atgcaataaa taagcatgat aatattgaaa
    33841 tattaggaca ccttggaaac ccaaactacc caatcgacta tgaattaatc attaaattag
    33901 ctatagaaaa gaatatctta atagaaataa ataattgttc tattaaaggc gtgtcaagaa
    33961 atggtagctc ggataactgt aagtatattg ctacactttg caaaaaatat ggtgctaaaa
    34021 tcatactgac ttcagatgct cacatttgtt ttgacatagg taactatgag tattctgaaa
    34081 atatcttaaa ggaaattaat tttccagatg aattaataat gaattatcct aaaaaactta
    34141 ttaatcattt tcaccaaaaa ggtaaattac tagatgttga ttatacaaat atctaagtaa
    34201 taatacatgc ttactttaac tcccataaaa attttaatac tatttatatt atatgaaata
    34261 aagaaattat aataaagaag ctatttaata aagcttaatt acttttatga acttgatgga
    34321 ttgatatggt ctatgatagc aatagaaatt ataacatttt taataaactt agttttatat
    34381 accttatagt ataaatctaa aaaagcatca tctaaaaagg agctgtcaca tgagcaaatt
    34441 aaatttgttc tatgatagct ctttttttac ttattttaat taggtatatt tttaattatt
    34501 ttatataaag cttatgttct aagtaaaatt atgcataaca aacaaaggta taaaaatacc
    34561 attttttcag ataatattta attataaata ataaatttag aatacttctt ttaaatgatg
    34621 agagtctaga aatttttatg tgtattcttt aaataaaaat ttccagactc tagccccttt
    34681 ttgaatattt taaaatttaa cttaaactaa gcaaattcta taatagctta tctctaaata
    34741 tttaaattta atttatcata caatattact tattataaaa cttaaaacat ataaaaatat
    34801 attttaaagc aataatttta ttttacttat taaatatttg gagttattaa aatcttttct
    34861 atctaaaaaa tattgatatt aaatatctaa taagaaaatt taat
//
LOCUS       DAEPKC010000034        34390 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.034, whole genome shotgun sequence.
ACCESSION   DAEPKC010000034 DAEPKC010000000
VERSION     DAEPKC010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 34390)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34390)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34390
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.034"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(142..498)
                     /locus_tag="KR294_001699"
                     /pseudo
     CDS             complement(142..498)
                     /locus_tag="KR294_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889008.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            890..1279
                     /locus_tag="KR294_001700"
     CDS             890..1279
                     /locus_tag="KR294_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBH0239780.1"
                     /translation="MKINKLPHAELKLMKYIWGVDDVLASRDIIEDMKLKYDWKKSTT
                     LTFLKNLVDKGFLTTDKVDRCTHYTIAIKEKDYLKVETKSFFSFMHNNSFKSFISALH
                     DDEVLDSKSLDKLEEYFKNLKEGDIDD"
     gene            1599..2108
                     /gene="vanZ1"
                     /locus_tag="KR294_001701"
     CDS             1599..2108
                     /gene="vanZ1"
                     /locus_tag="KR294_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ1"
                     /protein_id="HBH0239781.1"
                     /translation="MKSRKHNITKGLFIVYIIILTWIILFKLQFDISSLETMNLRSIN
                     LVPFAGSLIINNRVDISEIILNVAIFVPFGIYVCMLKEEWSFIKKVIPIFITSLAFET
                     LQYIFALGASDITDLIGNTLGGIIGIAVFMLLSKIFKNNTIKIINVLALIVTIIVVLF
                     LGLVIFANL"
     gene            complement(2210..2404)
                     /locus_tag="KR294_001702"
     CDS             complement(2210..2404)
                     /locus_tag="KR294_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase"
                     /protein_id="HBH0239782.1"
                     /translation="MSVIVMCSRCGKEIDKYRNKYITYYEKNTNAEIKVCINCALDLL
                     EKTRENQELNIQEFQDTIIL"
     gene            complement(2920..3312)
                     /locus_tag="KR294_001703"
     CDS             complement(2920..3312)
                     /locus_tag="KR294_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBH0239783.1"
                     /translation="MAALKSFEKPLTPEEEIEYLTKFKIENDKSAKDTLIERNMRLVA
                     YIAKKYNNSTEDQDDLISIGTIGLIKAIETYNIDKGTRLATYASRCIENEILMNIRSN
                     KKNKTQVSLQDPIGTDKEGNEINTTLYM"
     gene            3879..4241
                     /locus_tag="KR294_001704"
     CDS             3879..4241
                     /locus_tag="KR294_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239784.1"
                     /translation="MKIRKSGFISIECIISIAILYVAVYLVSTSLYNCYSFISRNISD
                     REMLSTAKKYIEDEKYRIQNSKYELIEDKIEKNYINGYEINSRIEQILDYYQCYEINI
                     EIKNEFKKLRFNSYVTRK"
     gene            4225..4932
                     /locus_tag="KR294_001705"
     CDS             4225..4932
                     /locus_tag="KR294_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239785.1"
                     /translation="MLLENKGSILIITLIIFSIISTVCIMCIGLIYTHNNMFELGYKD
                     IQLKEISLSGIEISVSNVLSCVEEAIDISNNEDEFREYFLGNNMIECIKKIKDTSYSS
                     LEELSLKVENNTIYDRGDFFEFDIESNVREKEFLKAIKVRVKIKNPWIGIDIEDYMDK
                     SNNNKIDDKTFNNYKASENNEIINQFKNESENIRNQEVVEFTEEDEEELKQNIIENIK
                     KNFDEKNLVQVYKYRGV"
     gene            4952..5371
                     /locus_tag="KR294_001706"
     CDS             4952..5371
                     /locus_tag="KR294_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239786.1"
                     /translation="MTVIELIVSISIILLIVTLSFPKDNLENHKINLFARQLCSDIRY
                     VRRINMFSNYNTYIYYINQGKHEGYVLRKDGKNIKSIMLPKNAKIARSIEIIKFKSDG
                     SPQKASTIEVYNNRLRKTITITPVSGRVLLKEGKYET"
     gene            5361..5885
                     /locus_tag="KR294_001707"
     CDS             5361..5885
                     /locus_tag="KR294_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239787.1"
                     /translation="MKHKYGYLLLESVVSLSSMVIIILVLYSIFLSTINLKLKVEDKI
                     ELQQQSLEIIKSMEGIISNSMGIMNVSNYEETFKKTTSIKCRYLDENNNEEGISNKEI
                     ILNERRNKLFVNSLNGESSQAGGYEIGDYVDEMYVSITNNGQYVNIKLKLSKCSQKYE
                     TDFKIKVWNFSESI"
     gene            6197..6754
                     /gene="efp"
                     /locus_tag="KR294_001708"
     CDS             6197..6754
                     /gene="efp"
                     /locus_tag="KR294_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HBH0239788.1"
                     /translation="MVSAGDFRKGVTFEKDGQPCLVVDFQHVKPGKGAAFVRTKYKNL
                     KTGAIREESFNPSEKFPKAVIDTRQMQYLYNDGELYYFMDQENFEQIPLNYEQVEDAI
                     KFLKENEVATIRFYQGQPFQVEAPNFAELEVTDTEPGIKGDTASNVTKAATVETGAVV
                     QVPLFINTGDKVKIDTRTGEYLSRV"
     gene            6846..7301
                     /locus_tag="KR294_001709"
     CDS             6846..7301
                     /locus_tag="KR294_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HBH0239789.1"
                     /translation="MKHLYEEVAYLKGLAEGLEISAESKEGKMIHKIVDALEVFADAI
                     VTLDEEQEELQDFVESIDEDLADLEEDIADMEEDLYEEDDDEDDEDFSYIEMECPNCG
                     ELVEIDEDLLYDDEVDVVCPDCKAVILSSEDDCDDDCTCGGCSSCDDRE"
     gene            7464..8174
                     /locus_tag="KR294_001710"
     CDS             7464..8174
                     /locus_tag="KR294_001710"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HBH0239790.1"
                     /translation="MKISKKLLDNIQRFENVINYKFKNKEYILEALTHSSYSNENKKY
                     NFNERLEFLGDSVLGIVISDYLFNEEANLPEGELTKLRANIVCEDSLSEVANDINLGI
                     HMLLGRGEEATGGRHRTSILADAFEAVIAAIYLDGGFESARQFILHHMENIIYDSRKG
                     NIFRDYKTHLQEVLQGNGENNIWYRLIEEKGPDHNKRFVMEVGINDDVLGIGEGKSKK
                     EAEQLAAKIALKKKLWEK"
     gene            8228..9298
                     /locus_tag="KR294_001711"
     CDS             8228..9298
                     /locus_tag="KR294_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBH0239791.1"
                     /translation="MKKRIIPIFVPHKGCPHDCIFCNQKKITGVSTDVTSEDARNIIE
                     ECLETIDKDADVEIAFFGGSFTAIDIDIQKSLLSVAKEYVEKGLVKDIRMSTRPDCID
                     EDILSMLKEYKTSIIELGVQSLDEKVLLDSIRGHQSEIVYKSSKMIKNSGIKLGLQMM
                     IGLPADTEEKCIFTAKKFVELKPDCVRVYPTLVVKDTGLEKLMEQNKYNPFTLEESVN
                     IVKKVLVLFYVNNINVIRVGLQATDDIQIGKAVLAGPYHPAFRELVEADMIKDYLEFV
                     ILQNKNIKQMLVKSNKKNISKIIGNKKTNVKYMEEKFGVLLKTQESDLDINQLEIVLD
                     GKSLISANMRDIHRKLYDIYDL"
     gene            9326..12880
                     /gene="smc"
                     /locus_tag="KR294_001712"
     CDS             9326..12880
                     /gene="smc"
                     /locus_tag="KR294_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HBH0239792.1"
                     /translation="MYLKRLELKGFKSFPVKTDIIFKEGITAIVGPNGSGKSNISDAV
                     RWVLGEQSIKSLRGDKLEDVIFAGTDTKKPMNYCEVALTIDNSENQLELDFTEVTIRR
                     RAYRNGESEFFLNNKSCRLKDIKEVFLDTGIGKDGYSIIEQGKVDEILSNNPLSRRKV
                     FDEACGISKYRYKKQEAERNLSNTKENLERIDDVYIEIENQLKPLFNQQTKAKKYLEI
                     SEKLKTLEVNSFIREIEGIEKELSEVNEHRKVIEKELNEKEEQKNVVEKKQEDINKEV
                     EVLQDVIEKSVDYINSIKGVISKKESQINLIKERIRNFTNEISRKNLEINDIKEKLNE
                     NKQYIKELESNKLSGSEELSTLQENIKVLEASKDKQKIKLESLNNEIELLKESIIDIL
                     NKKQEFSNKLSTLNANKENMNIRDENINSEITELNKNIEIKSSELDTINKEFNMQNEN
                     LKNVNNRHKELSTNLQDSISEHNKLEDEIQKSKYNLNGYNSKLNVYIDMENHYEGFNR
                     GVKEVLKNKNLKGVHGALGQIINVPEKYEKSIEAALGAYMQNIITDNEFSAKSAINYL
                     KQNNLGRVTFLPLNIIKSNKISLGNLKANTKFIGIASDLITFDEKYRNIIENILGRTI
                     LINNIDEGIKFAKETGHRFKIVTLDGEILNPGGSLTGGSLKTNGNILSRKRYINEYTE
                     KISNIKNEISHLELKRESLDKDVKNIKNEIDSHESKIKDLEKSIIIKSTSIKNVESEI
                     ESLKGSITKLENEKNDLNSNLNYTLEKSDDVRKDMEELDDLYNKNKEKIDALNEEIKR
                     YNDLYDKEKSEFDELNLSLVKKTEVYNSIVRDIKRISGENCELEEKNKQLEESLNYEE
                     HEIIKLQDSILTEEKEKENLTKQLGDSNRNLETRKIAKDDLKNSFDEINKELKTIDRQ
                     HIELKESLFKVGGRLERLKTSQDTYINKLFEQYDMTLVQALEIKDEDLDIDRKFLESL
                     KREIRSLGNINIDSIKEYEEIKERYDFYSEQKQDLEESMEEIEKLIHTLEENMKSEFE
                     IKFEEISKNFKYVYKRLFGGGCGELTILDKENLLESDILITAQPPGKKMKNLNLLSGG
                     EKALTAISILFAILITKPTPFCILDEIEAPLDDANIFRFGEFLKDLSKETQFISVTHR
                     RGTMEAADYIYGVTMQEKAISKVISLKLKEAQEITDII"
     gene            12907..14187
                     /gene="ftsY"
                     /locus_tag="KR294_001713"
     CDS             12907..14187
                     /gene="ftsY"
                     /locus_tag="KR294_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HBH0239793.1"
                     /translation="MLKKLFGFGKDKEKEIEKKDAEEEIEVEDSVDNLENLEETIFSG
                     LEEEVIDKVEDVEEKNEESVNNEGTEEIENFEKIEVEMDSNGKEVENISNNDSQEEII
                     EELENYDEIESKEIEDKEDKKVNLFERLKQGLTKAKQGITDRIDEVLKSYTKIDEELL
                     EDLEEILITADVGVNTTMDIIERLRDKIKQKGITEPIKVREELKSIVEDILTNENSTL
                     DIEPVPCIILMVGVNGVGKTTTIGKLANRYKKDGKKVLLAAADTFRAAATEQLEIWAN
                     RTNVDIIKHQEGADPGAVVFDAIKAAKARKTDVLICDTAGRLHNKANLMNELGKVFKI
                     VDREFPEAKREVLLVVDATTGQNAVVQAKTFKEVADITGIVLTKLDGTAKGGVVLAVK
                     SEVDVPVKLIGVGESVEDLQDFNAKSFSDALFGN"
     gene            14290..14658
                     /locus_tag="KR294_001714"
     CDS             14290..14658
                     /locus_tag="KR294_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HBH0239794.1"
                     /translation="MNIEKMVEIGLLFEQYKELLTDKQKEIVALYYEEDYSLGEISEN
                     LNVSRQGVYDTLKRSEKILRDYEEKLHLVSKIQEQEKNIKIIKDKIIDIKEDLLHNRD
                     CANLIPKLENIEDVCREMIK"
     gene            14655..16007
                     /gene="ffh"
                     /locus_tag="KR294_001715"
     CDS             14655..16007
                     /gene="ffh"
                     /locus_tag="KR294_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HBH0239795.1"
                     /translation="MIFEGLSDKLQGAFSKLKSKGKLTEVDVKNAMREVKLALLEADV
                     NFKVVKDFIKKVQERCVGQEVMQSLTPAQHVIKIVNEELTSLMGDVQSKVMISSKPPT
                     ILMMVGLQGAGKTTTAGKLGGYFKKQGKKPLLVACDIYRPAAIKQLQVVGEKLDIPVF
                     NMGDKENPVNIAKAGLSHAIKNANDLVIIDTAGRLHIDEVLMDELKSIKSEVKPHEIL
                     LVVDSMTGQDAVNVAESFNEALGVDGVVLTKLDGDTRGGAALSIRAVTQKPIKFMGMG
                     EKLDDIEPFHPDRMASRILGMGDVLSLIEKAQENIDLEKAKELEQKIKKQELDFEDFL
                     QQMEQIQNMGPLDKILGMIPGMGNVKDQLGDVDLNGKEMKRTKAIIQSMTTYERRNPG
                     VLNASRKKRIAKGSGTSVQDVNRLIKQLNEMKKMMKMFAGSQKSMKKRGGLGGLPFFK
                     "
     gene            16045..16317
                     /gene="rpsP"
                     /locus_tag="KR294_001716"
     CDS             16045..16317
                     /gene="rpsP"
                     /locus_tag="KR294_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HBH0239796.1"
                     /translation="MAVKIRLKRMGANKKPFYRIVVADSRAPRDGKFIEEIGYYNPIS
                     EPKQVRINDEKAIKWLATGAQPTEVVKKLLVKNGVIEKFEASKQAK"
     gene            16382..16609
                     /locus_tag="KR294_001717"
     CDS             16382..16609
                     /locus_tag="KR294_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HBH0239797.1"
                     /translation="MKELVVDIAKALVDNPDSVVVEEFEDNDGIVLKLTVAQEDMGKV
                     IGKQGRIAKAIRTVVRSVANRENIKVSLEIV"
     gene            16717..17232
                     /gene="rimM"
                     /locus_tag="KR294_001718"
     CDS             16717..17232
                     /gene="rimM"
                     /locus_tag="KR294_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA processing protein RimM"
                     /protein_id="HBH0239798.1"
                     /translation="MKEKLTHFKVGQIVNTQGLKGEVRVYPLTDDIERFDELKDFYLG
                     KDLNNKLAVEKVRYKGSMVIMKIKGIDSIEKAEKLKNKFMYVSREDSRELEEGEFFIA
                     DMIGMEVLTVDGKYVGILEDVLQYSANDVYVVKGEEDKEFMIPAIKKFVPTIDIDERK
                     MIIDPIKGMID"
     gene            17241..17936
                     /gene="trmD"
                     /locus_tag="KR294_001719"
     CDS             17241..17936
                     /gene="trmD"
                     /locus_tag="KR294_001719"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HBH0239799.1"
                     /translation="MRFHIMTLFPEIFNSYMDESIMKRAVEKGIIEVHIYNIRDFSNN
                     KHKKVDDYPFGGGAGMVMTPQPIYDTYKHIITTHNINNPSVIYLTPKGKVYNQSMAKQ
                     MSLKEDIILLCGHYEGIDERIIDLIVTDEISIGDYVLTGGELPALIMIDSISRLIPGV
                     LNQEESFEEESFKDNLLEYPHYTRPRDFEGLKVPEVLLSGNHKKIDEWRREESIRITK
                     ERRFDLYKKSNEK"
     gene            18121..18471
                     /gene="rplS"
                     /locus_tag="KR294_001720"
     CDS             18121..18471
                     /gene="rplS"
                     /locus_tag="KR294_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HBH0239800.1"
                     /translation="MNEMLRAIEQEQLKNEVPNFGPGDTVKVHVRIIEGKRERIQVFE
                     GVVLKRQGGGARETFTVRKMSFNVGVERTFPVHSPKIEKIEVTRKGKVRRAKLNYLRG
                     RVGKAAKIKEARNK"
     gene            18792..19688
                     /gene="ylqF"
                     /locus_tag="KR294_001721"
     CDS             18792..19688
                     /gene="ylqF"
                     /locus_tag="KR294_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HBH0239801.1"
                     /translation="MSNEYEEYLMDDNLHINWYPGHMKKTKELVKNNLKLIDVVIELL
                     DARIPFSSKNPDIDRLVGDKPRVVVLNKSDMADRDKLNQWIEYYKKINIKAIPVDTIK
                     GVGINKIIEECKNVTREKMSSLKDKGRKERAIRIMIVGVPNVGKSSLINKLTGRKSTQ
                     TGDKPGVTKGKQWVRLKGNLELLDTPGILWPKFEDQEVALNLAFSRAIKDEILDTETL
                     ALRLIEKLMKIEPEKLKARYKLDCLGETPIETMDMIGHKRGFITGKKELDYTRIATTV
                     LNEFRDGKIGNITLEVPENVKR"
     gene            20077..21369
                     /gene="brnQ"
                     /locus_tag="KR294_001722"
     CDS             20077..21369
                     /gene="brnQ"
                     /locus_tag="KR294_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HBH0239802.1"
                     /translation="MGKTKDVIVFGFALFAMFFGAGNLIFPPYLGIITGPEWLIAFLG
                     FTFADAGLALLAVMATAKFDGNVVEMFKRCGMKLGILIGCADILCIGPFLAIPRTGAT
                     TYEMGIMPLFGTSIPVLLFCILFFALSYVLTIRPSKVVDIVGQFLTPALLIALAFIII
                     KGIISPLGDIVDKPMIPNVFAEGIGQGYQTMDAFAAIALASVLIVSLNDKGYSTISDK
                     LKMIGKAGVLACGGLALVYGGLCFLGATVSTMYGTDAVQSQVIVNITEGLLGNVGKAI
                     LAVVVSLACLTTSIGLTSATGQYFSRLTKGKLSYEKIVLAVSVFSAVVASFGVGTIIK
                     IASPILSIVYPPSIVLIILAFFNEKIKNDNVYKGAVYMSLLVSILTVISSYGVAVPVV
                     NSLPLNSLGFNWVVPVIIAGIIGNFIPSKSQSNTLGTN"
     gene            22487..23779
                     /gene="brnQ"
                     /locus_tag="KR294_001723"
     CDS             22487..23779
                     /gene="brnQ"
                     /locus_tag="KR294_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HBH0239803.1"
                     /translation="MGEKQINFKDVIVIGFALFAMFFGAGNLIFPPYLGVLSGSSWLI
                     AFIGFLFADGGLALLAVIAATKFNGDTSKMFSRAGKGLSIALGCAMVICIGPLLAIPR
                     TAATTYEMGILPTIGSGISPVIFSIVFFALVLVLTIRPSKVVDIVGSILTPALLIALA
                     VLIVKGIISPLGEIRDSSLIQNVFAEGITQGYQTMDALAASVFASIIIMSVIAKGYTG
                     EKEKMKATISAGVIAVIGMALVYGGLCYLGATVSQQYGQDVQQTALIVAITAALLGTT
                     GKILLAIIVALACLTTAIGLSSAAGQYFSTLTDGKLKYEHIVIVVCVFSAIISNFGVS
                     TIIQFSSPILSMVYPATITLVILALFSNKIKNDNVFKCAAYMALLVSVLTVATSFGVK
                     IPLVNSLPFASLGFNWIVPVVIAGIIGNFIPSKSSKTA"
     gene            24353..26542
                     /locus_tag="KR294_001724"
     CDS             24353..26542
                     /locus_tag="KR294_001724"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobalamin-dependent
                     ribonucleoside-diphosphate reductase"
                     /protein_id="HBH0239804.1"
                     /translation="MKYIIKRDGTKELFSKSKIEDAVYKASINSEGGVDRELAYDISR
                     KIANDYNSMEKCLSVEEIQDIVEVLLMESNRKDIAKHYILYRERRSEIRTKAWEFDEL
                     QKSIWKNKYRHNGESFDEWIKRISNNSSRISKLIRQKRFLFAGRILANRGLQKEGKKV
                     TYSNCYVIEPPKDSIEDIFDTAKKLARTFSYGGGVGIDISKLRPKGAKVNNAAKHTTG
                     AVSFMELYSMTTGLIGQRGRRGALMISMDVNHPEIEDFIDIKTDLEKVTKANISVRVT
                     DEFMQAVREKKLYNCTFEVETTGEKIVKIVNAYDLFNKFVKNNWDYAEPGILFWDKIK
                     TYNFMSEDKNFCFSGVNPCAEEPLPSGGSCLLGSINLSEFIIQPFGEHATFDINKLKS
                     CVREAVVALNDVLDEGLNLHPLQEQRDSVHKYRQIGLGVMGIADMLIKMGIRYGSDES
                     LELCDLIGKTMLNEAVKQSALIAKEYGTFSEYKYENISKSKFFIENLNEDTKEMVKKY
                     GLRNSQLLTIPPTGSISTMIGISGGIEPIFNLSYIRKTESLHDEDVYYKVYTPIVKEY
                     MDKKGITDEECLPDFFVTAMNIGYEERINMQKVWQKYIDASISSTINIPFETTVEDVF
                     NIYIKAWEAGLKGVTIFRDGCKRSGILINEKKEENNKEDKKENSKKEYYKNNKKEKDN
                     KDEKAKEIINKNFEEDEKFVCPECGSEGIAHTGGCSICLKCGYSGCN"
     gene            26610..27377
                     /locus_tag="KR294_001725"
     CDS             26610..27377
                     /locus_tag="KR294_001725"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HBH0239805.1"
                     /translation="MQDKSVREIKEIIETLEVEKYMEYIELLRVDERKSVQGLAIKLA
                     KKLDNIRKEEERLETINIFENEGYDKGYLYIGGIDEAGRGPLAGPVVASVVVFKKDTK
                     IEGVNDSKKLSEAKRDELFEVIKEEALDYGIGIVNNEEIDEFNILNATYMAMKKAINC
                     LKKAPDYLLVDAATIPGIDISQNPIVKGDSKSISIAAASILAKVTRDSIMYQYDRVYP
                     EYGFKSHKGYGTKEHYEAIEKYGITPIHRKSFLKNIL"
     gene            27435..28451
                     /locus_tag="KR294_001726"
     CDS             27435..28451
                     /locus_tag="KR294_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HBH0239806.1"
                     /translation="MEYNELLKSARENLNGSCKVCKVCNGVACAGEVPGMGGKGSGSS
                     FIENSKSLEKVKVNMRVIHDVSNPDTSIEMFGKKMSAPIFAAPVTGTTLNMGGKINER
                     DYIEPVVAGCANSGIYAMVGDTAVDAFLMENLDVVKKYNGAGIVFIKPWDNENIIKKI
                     RLAEEAGAFAVGVDIDACGLVTLSLHGKPVLPKNVKQIKELVKSTKLPFILKGIMTVE
                     DALMAVEAGVDAIVVSNHGGRVLDCTPGACEVLPKIADAVKGKVTILADGGVRTGLDV
                     LKMIGLGADAVLIGRPFVTASFGGATDGVETYVNKLQSELSSSMILTGCQTIKDIDGK
                     VIYK"
     gene            28517..28765
                     /locus_tag="KR294_001727"
     CDS             28517..28765
                     /locus_tag="KR294_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239807.1"
                     /translation="MSRKAYEEALVELEKFIDERKEIIKSAEDCIDKYIVDRTLPFDY
                     KDKCVEWQQELLDIAEAQVLEANELSVLLQEKKELEED"
     gene            complement(28941..29438)
                     /locus_tag="KR294_001728"
     CDS             complement(28941..29438)
                     /locus_tag="KR294_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CarD family transcriptional regulator"
                     /protein_id="HBH0239808.1"
                     /translation="MYKIGESVMYPKEGACSVNDIVTKKINHEMQKYYELSVIFNSNL
                     KISIPVLNADRIGIRPVMDGNDVDNFIQSINKTDGVWIFDRKERLKLYQDKFHSGDVF
                     EIVKLIKMLMIQDSSKQLCSTDKEFLNKAQKFALSELAAAQCKSYTMVLEEMKKHILN
                     SKNTN"
     gene            complement(29682..30746)
                     /locus_tag="KR294_001729"
     CDS             complement(29682..30746)
                     /locus_tag="KR294_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0239809.1"
                     /translation="MIRLTIANIKRYLKNHNLLINMVMLPIILIFSLNFFINNSGNQS
                     MYFSPVAIVSDSSGKYEHKLINSSKLKENSFRLNELDKAMNLLKNNKVSAVFVLDKNF
                     SNSIDKLQRPVVKCFKIENGGGSLWAESQIESFITKSLKLKVDKNIDDKLTKTNIIDN
                     KPDKNKGSFLVVFLICYFMYINAAHLASDLFTLKKSNVLKRLISTDNKDIKIIFSIFL
                     GLFFIQSIVYTFALLCFSIIEDFNLSLNVLMIVLANSFVSTGFVFWVARVFKNESSIS
                     LISTFYSLIGLAISISSLIPSMDKLSFMTNLSKFTPFYWTIDAIKNNGSILINIIALI
                     LIGIIFVTAGSLKLRDFAKN"
     gene            complement(30749..31846)
                     /locus_tag="KR294_001730"
     CDS             complement(30749..31846)
                     /locus_tag="KR294_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0239810.1"
                     /translation="MKLYMSVKTMLKSLKSSFILNLIYFLALPLILSWFLGMVTESMF
                     QNPIKTESTPIVIYDKDNTRLSNDLTKYLKNDLSYILTVKKDDSKAELKLTIPKGYES
                     SLLNEKSNTLNIEKLGTRDDIAILLQDILDTYHEKFYLNNSQKISSEDFSKLFNKNSI
                     DTSIINNNVKQNSYEYFALVSLGFLVIIFIMNNILSNYISESKGLSKRLYSMPITRVQ
                     FLIYDFVGLWIYSFIFLLLYVLFFRILGITFKGNFAILLLLCALSSYFMTSISTFVTS
                     FFSKKYGTAIVYALLFLQTIFGGIFSMISDTFTKLTSLSPTYLIGELFSNYETFKTID
                     SIGDLIFTCLIISTILIALAIVKEKYKWREV"
     gene            complement(31860..32795)
                     /locus_tag="KR294_001731"
     CDS             complement(31860..32795)
                     /locus_tag="KR294_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0239811.1"
                     /translation="MDIVRVNNITKRFNDKLVLDNISFSVKKGEIFGLIGPNGAGKST
                     LINIITNLMLPNSGSIQINGLDLSKDYIKAKSIIGLVPQELAIIETLTPFDNLEYFGA
                     FYGLKGKLLKERIIEALEVTGLTEVKKKKVKKLSGGMQRRLNIGIALLNHPKILILDE
                     PTVGVDPQSRNHIFNFIKDISKKHETTVIYTSHYMEEVEHLCSKIFIMDEGKEIAFGD
                     NDYLKSLVSTNTKLIIEIKNINAQLIFDLKNTKGVISVLENNSLLELDIDKKLQLTDI
                     LSVIDKNNSKIMKISYEEPSLEDVFLNLTGKNLRD"
     gene            complement(32924..33571)
                     /locus_tag="KR294_001732"
     CDS             complement(32924..33571)
                     /locus_tag="KR294_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0239812.1"
                     /translation="MNKIKVLIVDDEKLIRKGLKIILSSYNDLEIVGDASNGYEALEF
                     CKMNDVDIVLMDIRMKVCDGVLGTRLIKEYNNSITLLILTTFNDDEYIKDAMKFGASG
                     YLLKDSSDEVLHEGIRSSFFGNIVLDKSVAEKIMTSEKTVKQEHLYDMYNLTEKEISI
                     IRLIANGLNNKEISQELFLSEGTIKNNITNILAKLELRDRTQLAIFAFKNKIVIE"
     gene            complement(33564..>34390)
                     /locus_tag="KR294_001733"
     CDS             complement(33564..>34390)
                     /locus_tag="KR294_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBH0239813.1"
                     /translation="LIISLDKNIYLALESSSILLIITVLSIYIENENLSKLYSQNLYD
                     KLRISKDELKKVNADLETYASSIEELAILKERNRISREIHDSVGHSLSTTIIQLNAIE
                     KLLKDKPLIYDLVHELREFVTESFQDVRRAISELKPVEYENYQSLFKIKELVKSFIKL
                     TNINVKLTISKNTWNLSRNQSITLYRLIQESLSNSSRHGKATEIRIFITFNTSNLIIT
                     ISDNGIGCGNIKKGNGLNSINERIYELNGKVEFDNSNNGFTIRASFPKFSGGDFFE"
BASE COUNT        14028 a         3483 c         5776 g        11103 t
ORIGIN      
        1 gatgctacaa aagttagtat aaaaaatgaa acaaacaata taatgaactt gtgtaattta
       61 cttagttgga atgctttatt acaaaataat aaaattaatg ctgaaacaat tgcaaaaagt
      121 agatatttta taatcatttt atcacctatt gatttctaca gattgtaagt agtatttggt
      181 tacacaagca cctcctttat tataacgtat tttttaaatt taaagatttt tccagatgtt
      241 atatttgact caaggtacat tgtaattaat ctaactataa gtggcaagta ctgtcctata
      301 ccaggaatag caccagccaa aagtcctgaa atccctatac cagcatcagt taaagttaat
      361 gcaactcctt tagaaagata taaattaaaa cctattctag cccaaactat tttatttatt
      421 tcagcttttc tataatataa ttcaagtagt gtcaatatcg ttcttcttaa ggtttttaat
      481 tagcttatat attgttattg tataatataa ttattaaaaa ttaactatat taaatattaa
      541 taaaaaatat agtaaaactt aataatacat acaataaaac ttaatataaa ttaagtatat
      601 gaaataaata tcctgtattt aagcttatag attttattaa atataataca tattataata
      661 ataaaacgaa ctaaaattat cacactaaag cataaaacat actctaatca tgttagataa
      721 atttttgaat atataatcca aaagtactct ctaaagtaga gtacttcttt tttattaatt
      781 atttttatat agaataaatt ggaatttata tttattccaa tctaattgat tatatacact
      841 tattgttata aagtttagtt atacataaat tggtaagagg tgtaaactaa tgaagattaa
      901 taaattacca catgcagaac taaaactaat gaagtatatt tggggagtag atgatgtatt
      961 agcctcaaga gatatcatag aagacatgaa gttgaaatac gattggaaaa agagcacaac
     1021 attgacattt ttaaaaaatt tagtagataa gggcttttta actactgata aggtagatag
     1081 atgtacgcat tatactatag ctataaaaga gaaagattac ttaaaagttg agacaaagag
     1141 tttttttagt tttatgcata acaattcatt taagagtttt atttcagcat tacatgatga
     1201 tgaagtttta gatagtaaga gcttggacaa gttagaagaa tactttaaaa atttgaaaga
     1261 aggagatatt gatgactaat aaagttatca gtatcttttt agtttgagac aattgagagt
     1321 agcgttttga tttaatgtta gttttatgtg atggtagaac attatataaa gaaaagtgat
     1381 tatttcctta gtgtttgata gtaaaaaata tagagaataa taccaattaa aatttaaaga
     1441 tatatgaaat actacaatag cttaaatcat gtaaatatga taaagatatt gaaattataa
     1501 aaggaatata attttagaag aaatagttga cagataaatt accttactat atcattgtat
     1561 taataaaata atacaatgat atagtaagga ggtaataaat gaaatctaga aaacataata
     1621 ttacaaaagg attatttata gtttacataa ttattttaac atggataata ctattcaagt
     1681 tgcaatttga tatttcatcc cttgaaacca tgaatcttag aagcataaac ttagtacctt
     1741 ttgctgggtc acttataatt aataatagag tagatatatc agagattata ttaaatgtgg
     1801 ctatatttgt accatttggg atatatgtgt gtatgctaaa agaagaatgg agctttataa
     1861 aaaaagttat acctattttt ataactagtt tggcatttga aacacttcaa tatatatttg
     1921 cactaggtgc aagtgatata acggatttga taggaaacac actaggagga atcataggaa
     1981 tagctgtttt tatgctatta tcgaaaatat ttaagaataa taccataaaa attatcaatg
     2041 tattggcatt gattgtgaca attattgttg tattattttt aggattagtt atttttgcaa
     2101 acttatagaa ataagtatat atgtttagct taaaatagaa cgtaagatac agttacatat
     2161 aaaattattt acacataaaa agcacctata caggtgcttt cctaaattat taaagaatta
     2221 ttgtatcttg aaactcttgt atgttcaatt cttgattttc tcttgttttt tctaataaat
     2281 ctaacgcaca atttatacaa actttaattt ctgcattggt atttttctca taataagtta
     2341 tatatttatt tctatattta tctatttctt ttccacaacg actacacatt acaattacgc
     2401 tcatatctta gttcctccat ctctaattat tcttaatata ttcaatagta tcacttttct
     2461 gaaaataatg attgttaaaa ctgtatcaaa tttagattta ctttttatta taatgcattt
     2521 taataaaaaa ataaaggtta taggtaaaat atttatagaa aaaagtatat tattgaatag
     2581 attataaaat tttattattt tttagcagta ttaaatacac attaatatct ataaaatgac
     2641 aaaataaaaa atactattta aatagatatt aaaaaattga taccaagtat ttgtttgcta
     2701 tatgaataac aatttattta ggagctttac ttggacactg tataataata aagtaattgc
     2761 taaaaacgtt tgatgatttg gatgtatttt tagaaattag aaaaatatat acttactgac
     2821 taatgataat cttatatgta ttttagtttg agtgatttaa gaaaagtgtt ttgaatgggg
     2881 attattttat agagtaaata aatatataat agtagaaaat tacatataaa gagtagtatt
     2941 tatttcatta ccttctttat ctgttccgat agggtcttgt agagatactt gagttttatt
     3001 ttttttgtta gatctaatat tcattaaaat ctcattttca atacatctag aagcatatgt
     3061 tgctaatcga gttcctttat ctatgttata agtttctata gctttaatta atcctattgt
     3121 acctatggat attaaatcat cctgatcttc cgttgaatta ttatatttct ttgctatata
     3181 agctactaat ctcatgtttc tttcaattaa tgtatctttt gcacttttat cgttttctat
     3241 tttaaattta gttaaatact caatctcttc ttcaggggtt aagggttttt caaaagattt
     3301 aagagctgcc aataggtcac ccccttttca acggtcactt taaattatat gaaggagact
     3361 tatccaagtt gactgttatc taataaaata atatgcatat ttttagaatt taaaacatat
     3421 atttgcaaac ttttgaatgg aatatgacat aaagagtggg aatttaaatt taagtttttg
     3481 ttgtatatat atgaaacaag gcgaagaaat tattgattta taaagtataa attggaattg
     3541 aggtgtcaat aaatataaaa ggaaatagta tttatatatg ttttggtgtt gaagtaaaag
     3601 attaatgcaa agcattagag tctataaaaa tatgaatata ggaggtgtaa ttttacaata
     3661 cttaaaaaag taaatgtaat taattgtttg tataaagttg attacaagca aaagtatcag
     3721 tcatagttaa tactgttaag gatgaaggtg gtgtgttaat ttatatatgt atgggaagaa
     3781 attttgatta caatgaaaaa acttacaaaa gatatttacg aaaaaactta tagttaaatg
     3841 tttatatata aaatattatt taggggttgt ttttattatt gaaaataaga aagagtggtt
     3901 ttatatcaat tgaatgtata ataagtattg ctatattata tgtggctgtt tatttagttt
     3961 ctacatcatt gtataattgt tatagtttta tcagtagaaa tatatctgac agagaaatgt
     4021 taagtacagc aaaaaaatat atagaagatg agaagtatag aatacaaaat agtaagtatg
     4081 agttaattga agataagata gaaaaaaatt acataaatgg atatgaaatt aacagtagaa
     4141 tagagcaaat tttagattat tatcaatgct atgaaataaa tatagagata aaaaatgaat
     4201 ttaaaaaact gaggtttaat agctatgtta ctagaaaata aaggctctat attaataata
     4261 acattgataa tattttctat tataagtact gtgtgcatta tgtgtatagg tttaatttat
     4321 acacataata atatgtttga gttaggatac aaagacattc aactaaaaga aatttcttta
     4381 agtggaatag aaatatcagt aagtaatgta ctttcttgtg ttgaggaagc tattgatata
     4441 tctaataatg aagacgaatt tagagaatat ttcttaggaa ataatatgat tgaatgtata
     4501 aaaaaaataa aagatacatc ttatagtagt ttagaagaac tttctttaaa agtagaaaat
     4561 aatactattt atgacagagg agattttttt gaatttgata tagaaagtaa tgttagagaa
     4621 aaagaatttt taaaagcaat aaaagtaaga gtgaaaatca aaaatccatg gataggaatt
     4681 gatattgaag attatatgga taaatctaat aacaataaaa ttgatgacaa aacattcaat
     4741 aattataaag catctgaaaa taatgaaatt ataaatcaat ttaaaaatga aagtgaaaat
     4801 ataaggaatc aagaggttgt tgaatttaca gaagaagatg aagaagaact taaacaaaac
     4861 ataattgaaa atataaagaa gaattttgat gaaaaaaacc tagtacaggt atataagtat
     4921 aggggtgtat aactttgaaa aaagaaggaa tgtgactgta atagaattaa tagtatctat
     4981 cagtataata ctcttgatag ttacattatc ttttccaaaa gataatcttg aaaatcataa
     5041 aataaattta tttgcacgtc aactttgttc agatataagg tatgttaggc gaattaatat
     5101 gtttagcaac tacaatacat atatatatta tataaatcaa ggtaaacacg aaggttatgt
     5161 attgagaaaa gatggtaaaa acattaaatc aataatgcta cctaaaaatg caaaaatagc
     5221 taggagtatt gaaataataa agtttaaatc tgatgggtcg cctcaaaagg cgtctacaat
     5281 agaggtatat aataatagat taagaaaaac tataacaata acacctgtaa gtggaagagt
     5341 acttctgaaa gagggaaaat atgaaacata aatatggtta cttgcttttg gaaagtgtcg
     5401 tatcattgtc ttcaatggtg ataattatac tagttttata ttctatattt ttgtctacaa
     5461 taaacttaaa gttaaaagta gaagataaga tagaactaca acaacaaagt cttgaaatca
     5521 taaaatctat ggaaggaatt attagcaatt ctatgggaat aatgaatgta tctaattatg
     5581 aagaaacatt taaaaagaca acatctataa aatgtagata tttagatgaa aataataatg
     5641 aagaaggcat aagtaataaa gaaattatat tgaatgaaag acgaaataag ttatttgtaa
     5701 attctttaaa tggcgaaagt agtcaagcag gtggttatga aattggagat tatgtagatg
     5761 aaatgtatgt atcaattact aataatggtc aatacgttaa tattaaattg aaattatcaa
     5821 aatgtagtca aaaatatgag actgatttca aaataaaagt atggaatttt agtgaaagta
     5881 tataaaaata cataaattta agagaaagaa atgacatcaa taagtcatat aaaatataat
     5941 tattgagaac tatataacta aataatatca atatgtaaag tgtatagatt aagaatatag
     6001 aggataataa taaaaatata gaataagtaa tttgccaaat acttgtttat attgtataac
     6061 ttatgatatt atgatattag taaaaatttg taatcctgac ttgacagaat tcaagtaaga
     6121 gatataattt taaaggcata gtaatgtaaa atttactaaa aaataagaaa tttattttaa
     6181 tatggaggaa caaaaaatgg tatcagcagg tgattttaga aaaggtgtta catttgaaaa
     6241 agatggacaa ccatgtttag tagttgattt tcaacacgtt aagccaggta aaggagctgc
     6301 tttcgttaga actaaataca aaaacttaaa aacaggagct ataagagaag aaagtttcaa
     6361 tccaagtgaa aaattcccta aagctgttat agatacaaga caaatgcaat atctatacaa
     6421 tgatggtgag ttatattatt ttatggatca agaaaatttt gaacaaatac cattaaacta
     6481 tgagcaagtt gaagatgcaa ttaagttctt aaaagaaaat gaagttgcta caataagatt
     6541 ttaccaagga caaccattcc aagtggaagc gccaaacttt gcagagctag aagttacaga
     6601 tacagagcca ggcataaaag gtgatacagc aagtaatgta actaaagcag ctacagttga
     6661 aactggagca gttgttcaag ttccattatt tataaatact ggagataaag taaagataga
     6721 tactagaaca ggtgaatatt tatcaagagt ataaaaattt atgtatataa aagcttatat
     6781 gtcttaataa tataagatat atgagctttt agtttatata taaaaaagaa agcgaggggt
     6841 gttacatgaa acatttatat gaagaagttg catacttaaa aggcctagca gaaggactag
     6901 aaataagtgc tgaaagtaaa gaagggaaaa tgatacataa aatagttgat gcattagaag
     6961 tatttgcaga tgctattgta acattggatg aagaacaaga agaacttcaa gattttgttg
     7021 aatctataga tgaagattta gcagatttag aagaagatat tgctgacatg gaagaagatc
     7081 tttatgaaga agatgacgat gaggatgatg aggacttcag ctatatagaa atggaatgcc
     7141 caaattgtgg agagttagta gaaatagacg aagatttgtt atatgatgat gaagtagatg
     7201 ttgtttgtcc tgattgtaag gctgtgatat tatcatcaga agatgattgt gatgatgatt
     7261 gtacatgtgg tggttgttca agttgtgatg atagagagta aaaattcata agaattaaaa
     7321 ctgcctatga tgcctatgag atattttgct tcataggtag ttttattttt atgaggaagg
     7381 gtattatgta ttttggtttt gcaatacttg gacaaaaata gtacactaga atttatagaa
     7441 taggattttg gagggatgta aatatgaaaa taagtaaaaa attactagat aatatacaaa
     7501 gatttgaaaa tgttataaat tataaattta aaaataaaga atatatacta gaagctctta
     7561 ctcatagttc atattctaat gaaaataaaa aatataattt taacgaaaga ttggaatttt
     7621 taggggattc ggttttaggc atagtgataa gtgattattt atttaatgaa gaagctaatc
     7681 tgcccgaagg ggaactaact aaacttagag caaatatagt ctgtgaagat tcattaagtg
     7741 aagtagctaa tgatataaat ttaggtattc acatgttatt aggtagagga gaagaagcaa
     7801 caggaggaag acataggact tcaatattag cagacgcatt tgaagctgta atagctgcta
     7861 tatatcttga tggaggtttt gaaagtgcaa gacagtttat acttcatcat atggaaaata
     7921 taatttatga ttcaagaaaa ggaaatatat ttagagacta caaaacgcat cttcaagagg
     7981 tgttacaagg gaatggagaa aataatatct ggtacaggct tatagaagaa aaaggaccag
     8041 accataataa aagatttgta atggaagttg gaattaatga cgatgtactt ggtataggag
     8101 aaggcaagag taaaaaagaa gctgaacagt tagctgctaa aatagcttta aagaaaaaat
     8161 tatgggaaaa ataaatataa tatgtaaaaa tataaaaaga aatatttata ttagaaggat
     8221 gttgtagatg aaaaagagaa ttatacctat atttgttcct cacaaaggat gtcctcatga
     8281 ttgcatattt tgtaatcaaa aaaaaataac aggtgtgagt actgatgtta ctagtgaaga
     8341 tgcaagaaat ataattgagg aatgtttaga gactatagat aaagatgcag atgtagaaat
     8401 agcatttttt ggtggtagct ttactgctat agatattgat atacaaaaaa gtttattatc
     8461 agttgctaaa gaatatgtag aaaaaggtct tgtaaaagat attagaatgt ctacaagacc
     8521 agattgtatt gatgaagata tattaagtat gttaaaagaa tataagacaa gtataattga
     8581 actaggagta caatccttag atgaaaaagt attattagat agtataagag gtcatcaatc
     8641 tgaaattgta tacaagagtt caaagatgat aaaaaatagt ggaatcaaac ttggattaca
     8701 gatgatgatt ggtcttccag ctgacacaga agaaaagtgt atatttacag caaaaaaatt
     8761 tgtagagcta aaaccagatt gtgttagagt ctatccaact ttggtagtaa aagatacagg
     8821 tcttgaaaag ttaatggaac aaaataaata taatccattt acccttgaag agagtgtaaa
     8881 tatagtaaaa aaagttcttg tactgtttta tgttaataat atcaatgtaa taagagttgg
     8941 gcttcaagct actgatgata tacaaattgg aaaagctgtt ttagcaggac catatcatcc
     9001 tgcatttaga gagttggtag aagcagatat gataaaagat tatttagaat ttgttatttt
     9061 gcaaaataaa aatataaagc aaatgttggt caaatctaat aaaaagaata tttctaaaat
     9121 cataggaaat aaaaaaacaa atgttaaata tatggaagaa aaatttggtg tgcttttaaa
     9181 aacacaagaa tcagatttag atataaatca attagaaatt gtgttagatg ggaaaagttt
     9241 aattagtgct aatatgagag acattcatag aaaattgtat gacatttatg acctttagtt
     9301 ttaataatga agggagagaa aagatttgta tttaaaaaga ctagagttaa agggatttaa
     9361 atcctttcca gtaaaaacag atattatttt taaagaagga ataacagcca tagtaggacc
     9421 aaatgggagt ggaaaaagta atatatctga tgctgtaaga tgggtattag gagaacagag
     9481 tattaagagt cttagaggtg ataaactcga agatgtaata tttgcaggta cagatacaaa
     9541 aaaacctatg aattattgtg aagtggctct tactattgat aattctgaaa atcaattgga
     9601 attagatttt acagaagtaa ctataagaag aagggcttat agaaatggtg aaagtgaatt
     9661 ttttctaaat aataaaagtt gtagattaaa agatataaaa gaagtctttt tagatactgg
     9721 tattggaaaa gatggttatt caatcataga acaaggaaaa gtagatgaaa tattaagtaa
     9781 taatccttta agcagaagaa aagtttttga tgaagcttgt ggcatatcaa aatatagata
     9841 taaaaaacag gaagcagaaa ggaatttaag taatacaaag gaaaatttag aaagaataga
     9901 tgatgtatat atagaaattg aaaatcaatt aaagcctctt tttaatcaac agacaaaggc
     9961 aaaaaagtac ttggaaataa gtgaaaaatt aaagacactt gaagtaaata gctttataag
    10021 agaaattgaa ggaatagaaa aagaattaag tgaggttaat gaacatcgta aggttattga
    10081 aaaggagctc aatgaaaaag aagaacaaaa aaatgttgta gagaaaaagc aagaagatat
    10141 taataaagag gtagaggtat tacaagatgt aattgaaaaa tctgtagatt atataaattc
    10201 aattaaagga gttatatcaa aaaaagagtc ccaaataaat ttaattaagg aaagaataag
    10261 aaattttacg aatgaaatta gtagaaaaaa tttagaaata aatgatataa aagagaagct
    10321 aaatgaaaat aagcaataca taaaagaatt agaaagcaat aaattatcag gtagtgaaga
    10381 actatctacc ttgcaggaaa atataaaagt attggaagca agtaaagata aacaaaaaat
    10441 taagttagaa tccctaaata atgagataga attattgaaa gaaagtataa ttgatatatt
    10501 aaataaaaaa caagagttta gtaataagct gtccacttta aacgcaaata aagaaaatat
    10561 gaatatcaga gatgaaaata taaattcaga gataacagag ttaaacaaaa atattgaaat
    10621 aaaatcatct gaattagata ctataaataa agaatttaat atgcaaaatg aaaatttaaa
    10681 gaatgtaaat aatagacata aagaattatc aactaatttg caggattcaa ttagtgaaca
    10741 caataaacta gaagatgaaa tacagaaaag taaatataat ttaaatggat ataattcaaa
    10801 gttaaatgtc tatatagata tggaaaatca ttatgaagga tttaatagag gagtaaaaga
    10861 agtactaaaa aataaaaatt taaaaggagt tcatggagca ttaggacaga ttataaatgt
    10921 acctgaaaaa tatgagaaat ctatagaagc agctcttggt gcttatatgc aaaatataat
    10981 aactgataat gagtttagtg ctaagtctgc aataaactat ctaaaacaga ataatttagg
    11041 tagagtaaca tttcttccat taaatataat taaatcaaat aaaataagtc taggaaattt
    11101 aaaagcaaat actaagttca taggaatagc aagtgattta attacatttg atgaaaagta
    11161 tagaaatata attgaaaata tacttggaag aacaatactt ataaataata tagatgaggg
    11221 cataaaattt gcaaaagaaa ctggtcatag gtttaaaata gtaactttag atggtgaaat
    11281 cttaaatcca ggaggttctt tgactggggg aagtctaaaa actaatggga atatactatc
    11341 cagaaaaaga tacattaatg aatatacaga aaagataagt aatatcaaga atgaaatttc
    11401 acatctagaa ttaaaaagag aatctttaga caaagatgtg aaaaatatca aaaatgaaat
    11461 tgattcacat gaaagtaaaa taaaagattt agaaaaaagt ataataataa aaagtacaag
    11521 tataaagaat gttgagtctg aaattgaatc gttaaaaggt agtattacta aattagaaaa
    11581 tgagaagaat gatttaaatt ctaacctaaa ttatacactt gaaaaaagtg atgatgttag
    11641 aaaagatatg gaagagttag atgatttata caataaaaat aaagaaaaaa ttgatgcatt
    11701 gaatgaggaa ataaaaagat acaatgattt atatgataaa gaaaaatctg aatttgatga
    11761 attgaactta agtttagtga agaaaacaga agtttacaat agtatagtta gagatataaa
    11821 aagaatatct ggtgaaaatt gtgagctaga agaaaaaaat aaacaattag aagagtcatt
    11881 aaattatgaa gaacatgaaa taattaaatt acaagattct atactcactg aagaaaaaga
    11941 aaaagaaaat ttaacaaaac aactagggga tagtaataga aatcttgaaa ctagaaaaat
    12001 agcaaaagat gatttaaaaa atagttttga tgaaattaat aaagaattaa aaactataga
    12061 tagacagcat atagaactta aagaaagttt atttaaagtt ggtggaagat tagaaagatt
    12121 aaaaactagt caagacacat atataaataa gttgtttgag caatatgata tgaccttagt
    12181 acaagcattg gaaattaaag atgaagattt ggatatagat agaaaattct tagaaagtct
    12241 aaagagagaa ataagaagtc ttggaaatat aaatatagac tctataaagg aatatgagga
    12301 aataaaagaa agatacgatt tttatagcga acaaaagcaa gatttagaag agtctatgga
    12361 agagatagaa aaacttatac atactttaga agaaaatatg aaatctgaat ttgaaattaa
    12421 gtttgaagaa ataagtaaaa attttaaata tgtatataag agattatttg gtggaggttg
    12481 tggagaatta actattttag ataaagaaaa tttattagaa agtgatatac taataacagc
    12541 tcaaccccca ggtaaaaaaa tgaaaaattt aaacctatta tctggtggag agaaagcttt
    12601 aacggcaata agtatattat ttgctatatt gattacaaag ccaacaccat tttgtatatt
    12661 agatgagatt gaagcgccac ttgatgacgc aaatatattt agatttggag aatttttgaa
    12721 ggatttatct aaagagactc aatttatatc agtaactcat aggagaggaa ctatggaagc
    12781 tgctgattat atctacggag ttacaatgca agaaaaagcc atttcaaaag ttattagttt
    12841 aaaattaaaa gaagctcagg aaataacaga tattatataa cttagattga cataggagga
    12901 ataacagtgt taaaaaaatt atttggtttt ggaaaagaca aggaaaagga aatagaaaaa
    12961 aaagatgctg aagaagaaat agaagttgaa gacagtgttg ataatttaga aaacttggaa
    13021 gaaactattt tttcaggact tgaagaagaa gtgatagata aagtggaaga tgttgaagaa
    13081 aaaaatgagg aaagtgtcaa taatgaaggc actgaagaaa tcgaaaactt tgaaaaaata
    13141 gaagttgaga tggatagtaa tggaaaagaa gtagaaaata tttcaaataa tgattctcaa
    13201 gaagagataa tcgaagaatt agaaaattat gatgaaattg agtctaaaga gatagaagat
    13261 aaagaagata agaaagttaa cttgtttgaa agactaaaac aaggattgac aaaagcaaag
    13321 caaggaataa ctgatagaat agatgaagtt ttaaaatcat atacaaagat agatgaagaa
    13381 ttacttgaag atttagagga aattttaata acagcagatg ttggtgtaaa tacaactatg
    13441 gatataattg aaagactaag agataaaata aagcaaaaag gtattactga accaataaag
    13501 gtaagagaag aacttaaatc tatagttgaa gatattctta caaatgaaaa ctctacacta
    13561 gatatagaac cagtaccatg tataatatta atggtgggtg taaatggggt cggtaagact
    13621 actacaatag gtaaactagc aaatagatac aaaaaagatg gtaaaaaagt tttattagca
    13681 gcagcagata catttagagc agcagcaaca gagcaattag aaatttgggc aaatagaacc
    13741 aatgtagaca taataaaaca tcaagaggga gcagaccctg gagctgtagt atttgatgct
    13801 ataaaagctg caaaagctag aaaaacagat gtattaatat gtgatacagc aggaagatta
    13861 cacaataagg ctaatcttat gaatgaactt ggaaaagtat ttaaaatagt agatagagaa
    13921 tttccagaag caaaacgaga agtacttctt gtggtggatg ctacaacagg tcaaaatgca
    13981 gttgttcaag caaagacatt taaagaagtt gcagatataa caggtatagt acttacaaaa
    14041 cttgatggaa ctgcaaaagg tggagtagtc cttgcggtaa aatcagaagt agatgtacct
    14101 gtaaaactta ttggagttgg agaaagtgta gaagacctac aagatttcaa tgcaaaatca
    14161 ttttcagatg cattatttgg taactaatgt tcttttaaaa ataatggttg acaagagtgt
    14221 tgttatgata taaaatacaa tagtgtaaag taaataacct ttacagtata ctgctaggaa
    14281 gtgtaagata tgaatataga aaaaatggtc gaaattggat tgttatttga acagtataaa
    14341 gaattattaa ctgacaagca gaaagaaata gttgctctat actatgaaga agattattct
    14401 ttaggtgaaa ttagtgaaaa tctgaatgta tcaagacaag gtgtttatga taccttaaag
    14461 cgttcagaaa aaatactaag agattatgaa gaaaagttac acttagtatc aaagattcaa
    14521 gagcaggaaa aaaatattaa gattataaaa gataaaatta ttgacattaa agaagattta
    14581 ttgcacaata gagattgtgc taatttaatc cctaagctag aaaatataga agatgtatgt
    14641 agggagatga taaaatgata tttgaaggat tgtctgataa actacaaggg gcatttagta
    14701 agttaaaatc taaaggaaaa cttacagaag tagatgtaaa aaatgctatg agagaagtta
    14761 aacttgctct tcttgaggca gatgttaact ttaaagtagt taaagatttc ataaaaaaag
    14821 ttcaagagag atgtgttggg caagaagtta tgcaaagctt aactccagct cagcatgtaa
    14881 tcaaaattgt aaatgaagag cttacaagtt taatgggaga tgtacaaagt aaagtaatga
    14941 tttcctcaaa gcctcctaca attttaatga tggttggatt gcaaggtgca ggtaagacta
    15001 ctacagcagg aaaacttgga ggatatttta aaaagcaagg taaaaaacct ctattagtag
    15061 cttgtgatat ttatagacca gcagctataa agcaacttca agttgttgga gaaaaattgg
    15121 atatacctgt attcaatatg ggagataaag aaaatccagt aaatattgcg aaagcaggtt
    15181 taagccatgc gattaaaaat gctaatgatt tagttattat agatacagct ggtagacttc
    15241 atatagatga agtacttatg gatgagttaa agtctattaa atcagaagtt aagccacatg
    15301 agatactttt ggttgtagat tctatgacag gtcaagatgc tgtaaatgtt gcagaaagct
    15361 tcaatgaggc acttggtgtt gatggagtag tattaactaa attggatgga gatactagag
    15421 gaggtgctgc actttcaata agagcagtta cacaaaagcc tataaaattt atggggatgg
    15481 gagaaaagct agatgatata gaacctttcc acccagatag aatggcatca agaatattag
    15541 gtatgggaga tgtcttaagt ttaatagaaa aagcacaaga aaatatagat ttagagaaag
    15601 ctaaagaatt agagcaaaaa attaaaaaac aagagcttga ttttgaagat ttcttacaac
    15661 aaatggaaca aatacaaaat atgggacctc ttgacaagat acttggtatg atacctggta
    15721 tgggaaatgt aaaagaccaa cttggagatg tagatttgaa tggcaaagaa atgaagagaa
    15781 caaaagccat aattcagtca atgactacat atgagagaag aaacccagga gtattaaatg
    15841 cttcaagaaa gaaaagaata gctaaaggca gtggaactag tgtacaagat gtaaatagac
    15901 ttataaaaca acttaatgaa atgaaaaaaa tgatgaagat gtttgctggt tcacaaaaga
    15961 gtatgaagaa aaggggcggc ttaggcggtt tacctttttt taaataaaat ataaaaaagt
    16021 aaaaattatt cggaggtgac tgtaatggca gttaaaataa gattaaaaag aatgggagct
    16081 aacaaaaaac ctttctacag aatagtagta gctgattcaa gagctccaag agatggaaaa
    16141 tttatagaag aaataggata ctataatcca atttctgaac ctaaacaagt aagaataaat
    16201 gatgaaaaag ctataaaatg gttagctact ggtgctcagc caacagaagt agttaaaaaa
    16261 ttacttgtaa aaaacggagt aatagaaaaa ttcgaagctt ctaaacaagc aaaataattt
    16321 tttcttggca attagtttaa gtaagggctc attgctaagg ttactttagg agatgaaata
    16381 tatgaaagag ctagttgtag atatagctaa ggctctagtt gataatcctg actcagttgt
    16441 tgttgaggaa tttgaagata atgatggtat cgtcttaaag cttacagttg ctcaagagga
    16501 tatgggtaag gttattggga agcagggaag aatagctaaa gctataagaa ctgtcgtaag
    16561 atctgttgca aatagagaaa atataaaagt ttctcttgag atagtataaa ataggaggat
    16621 taggtataat gcctagtcct ttttatataa atgcgtagtt taagatttta tgatgatatg
    16681 accacataag attaaatttt ttaagaaggt gataacatga aagaaaaatt aactcatttt
    16741 aaggtaggtc aaatagtaaa tacacaaggt ttaaaaggtg aagtaagagt ttatccgctt
    16801 actgatgata tagagaggtt tgatgaatta aaagatttct atctgggaaa agatttaaat
    16861 aataaattgg ctgttgaaaa agtaagatac aaaggttcta tggttataat gaagataaaa
    16921 ggcatagaca gcatagagaa agcagaaaaa ctaaaaaata aatttatgta tgtatctaga
    16981 gaagatagca gagagcttga agaaggcgaa ttttttatag cagatatgat tggaatggaa
    17041 gttttaactg tagatggaaa atatgtagga atactagaag atgttcttca atactcagca
    17101 aatgatgtct atgtagtaaa aggtgaggaa gataaagaat ttatgatacc agctataaaa
    17161 aaatttgtac ctacaataga tattgatgaa agaaaaatga ttatagaccc tattaaggga
    17221 atgatagatt aggtggtaat atgagatttc atataatgac actttttcca gaaatattta
    17281 attcgtacat ggatgaaagt ataatgaaga gagcagttga aaaaggtata attgaggttc
    17341 atatatataa tataagggat ttttctaata ataaacataa aaaagtagat gattatccat
    17401 ttggaggagg agcggggatg gtaatgactc ctcaacctat atatgacaca tataagcata
    17461 taataacaac tcataatata aataacccaa gtgtaattta tcttactcca aaaggtaagg
    17521 tatacaatca atctatggca aagcagatgt ctttaaaaga agatataata ctactatgtg
    17581 gtcattatga aggaatagat gagagaatca ttgatttaat agttactgat gaaatttcaa
    17641 ttggagatta tgtattaact gggggagagc tcccagcact tataatgata gattctatat
    17701 cgagattaat accaggtgta ttaaaccaag aagaatcatt tgaagaagaa tcatttaaag
    17761 acaacttatt ggaatatcct cattacacta gacctagaga ttttgaagga ttaaaagtac
    17821 cagaagtgct tttatcaggg aatcataaga agatagatga gtggagaaga gaagaatcta
    17881 taaggataac caaagaaaga cgatttgatt tatataaaaa gtctaatgaa aaataaaaat
    17941 ataatgaaaa attaatatat atgtatacaa taaagtacct ataaatggaa ttaaaaacat
    18001 aaaagtgctt gtaataacta ttgaagtata gtataatata aaatgttgaa aatacgggcg
    18061 ttcctctgtt tacactggtc gggtagttaa gaacgtctat gatatctagg aggaagaaag
    18121 atgaatgaaa tgctaagagc aattgagcaa gaacaattaa aaaatgaagt tcctaatttt
    18181 ggacctgggg acacagttaa agtacacgtt agaattatag aaggaaaaag agaaagaata
    18241 caagtattcg aaggtgtagt attaaagaga caaggtggag gagcaagaga aactttcaca
    18301 gttagaaaaa tgtctttcaa tgttggtgta gaaagaactt tcccagttca ctctccaaaa
    18361 atagaaaaaa tagaagttac tagaaaaggt aaagtaagaa gagctaaact aaactactta
    18421 agaggtagag taggtaaagc tgctaagata aaagaagcta gaaataaata attaaaaact
    18481 ttacttataa atggggggct gatttatcag tcctctttct attttaatga aaattacaac
    18541 aaataattat actagaaata aatagaaata tttgttgaaa atatagatta tttatctatg
    18601 aatttatagc ttttaaaatg aaaaataaaa ttggtaaata ttgcattata ttttgtaacg
    18661 atattaaaaa taagagaaca gtattatgta aagtatgacg ttaaaaagat gacaatatta
    18721 tagtttgtga agatatattt tttaagtgga attaggatat aataatataa tattaataag
    18781 gagtgataca tgtgtcaaat gaatacgaag agtatcttat ggatgacaat ctacatataa
    18841 actggtatcc aggtcatatg aaaaaaacta aggagttagt aaaaaataac ttaaaattga
    18901 ttgatgtagt aattgaactt ttggatgcta gaatcccgtt tagtagtaaa aatccagaca
    18961 tagacaggct tgtaggagat aagccaagag ttgtcgtact taataagagt gatatggcag
    19021 atagggataa attgaatcaa tggattgaat actataagaa aattaatatc aaagctatac
    19081 cagtagatac aataaaaggt gttggtataa ataagataat cgaagaatgt aaaaatgtaa
    19141 ctagagaaaa aatgagttct ttaaaagaca aagggagaaa agaaagagct atacgaataa
    19201 tgatagttgg cgttccaaat gttggtaaat cgtctcttat aaacaaatta acaggtagaa
    19261 aaagcactca aactggagat aagccaggag taacgaaagg gaaacaatgg gttagattaa
    19321 agggaaatct tgaactttta gatacgcctg gaatactttg gcctaagttt gaagaccaag
    19381 aagttgcatt aaatttagca tttagtagag ctataaagga tgagatttta gatactgaaa
    19441 ctttggcttt aagacttata gaaaaactta tgaaaataga acctgagaag ttgaaagcca
    19501 gatataagtt agattgtcta ggagaaactc caattgaaac tatggatatg attggtcata
    19561 aaagaggatt tataacaggt aaaaaagaac tagattatac acgcatagcc acaactgtat
    19621 taaatgaatt tagagatgga aaaataggaa atataacatt ggaagttcca gaaaacgtta
    19681 aaagatagat tttaaaacaa aatcaaaaat ttaatgttaa aaatttaaaa aagcctttta
    19741 gcaaaggctt ttttattttt ttgaaatata gacaaatatc tccatataaa agtataaatt
    19801 aggttagaaa gcctttaaaa atattaattt aagacaaata tacctaatat tttgaaaatt
    19861 aaaatgagtg tgattattaa aaattttagc atattgactt gcttgtttcg tataatatat
    19921 aataagcaca aataaataca atatattaaa aatttaattt atttaatttt attaatttaa
    19981 taataagttc ttattgttta attcaactta cttatgcaag cgtaaacaat cgagacattt
    20041 tattaattta ataaggttaa aaagggggat tttataatgg gtaagaccaa ggatgttata
    20101 gtatttggat ttgcgttatt tgcaatgttc tttggagcag gtaacttaat atttccacct
    20161 tacttgggaa taattacagg tccagaatgg ttaattgcct tcttaggatt tacgtttgct
    20221 gatgctggat tggcacttct agcagtaatg gctacagcta aattcgatgg aaacgtagtt
    20281 gaaatgttta aaagatgtgg tatgaagtta gggattctta taggttgtgc agatatttta
    20341 tgtataggac cattcttagc tataccaaga acaggtgcaa caacttatga aatgggtata
    20401 atgcctttat ttggaacttc aattccagtg ttattattct gtatactttt ttttgcgctt
    20461 tcatatgtac taacaataag accttctaag gtcgtagata tagttggaca gtttttaact
    20521 ccagctcttt taatagcttt agcatttata attataaaag gtattatatc acctcttgga
    20581 gatatagtag ataaacctat gatacctaat gtatttgcag aaggtatagg tcaaggatat
    20641 cagacaatgg atgcttttgc agcaatagca cttgcatcag ttctaatagt atctttaaat
    20701 gataaaggat attctactat tagtgacaag ttaaaaatga ttggtaaggc gggtgttctt
    20761 gcttgtggag gattagctct agtttatgga ggattatgtt tccttggagc aactgtatca
    20821 acaatgtatg gaacagatgc agtacaatca caagtaatag taaatataac tgaaggattg
    20881 cttggaaatg ttgggaaagc gattttagca gtagtagtat cattagcatg tttaactaca
    20941 tctataggtc ttacatctgc cacaggtcaa tatttctcta gacttacaaa aggtaagttg
    21001 agttatgaaa aaatagtatt agctgtatct gtattcagtg cagtagtagc atcttttggt
    21061 gttggaacta taataaagat agcatctcct atattaagta tagtttatcc accatcaatt
    21121 gttttaataa ttttagcttt cttcaatgaa aaaattaaga atgataatgt gtacaaagga
    21181 gcagtatata tgtcattgct tgtaagtata ctaacagtta tatctagtta tggagtagct
    21241 gttccagtag taaactcttt acctcttaat tcattaggat ttaactgggt ggtgcctgtt
    21301 ataatagctg gaataattgg caattttata ccatcaaaga gtcaatctaa tacacttgga
    21361 acaaactaag ttttatttaa ttaaaatata atcaattgta aataaatgag ttaactaaaa
    21421 gtaaaaggag ttatttgtac aaataactcc ttttattttt agattctata cttaattatt
    21481 tgtatttaat atggaaaaag tataagaaaa tatcaaaaaa atatatagtt tattttttaa
    21541 cgataataga gattaaaaaa gaattttaga gtaattttat aaatttaagt atacatatta
    21601 aatgattttt acaaaaatat aatataaata aaattgtgac aataataaaa taataaaaca
    21661 aaatttaaga catatgatta tataaatgta ttaagtaaat gggtaaattg ttttcattga
    21721 gagatatatt aagaattttt agttaattat gacagataag tatgtaaacg tgaatactag
    21781 caactgcaaa gtttaagtaa gttggaagtt agaaagtaat tgatatgaag aaaaataagt
    21841 tgataaatca taataaggaa ttttcagaaa aaatgatttt aagactaaaa aacaagaggc
    21901 aaatctacat aaatagaata aaaaacgaat aaagttaact gtcaatttag caaaataaat
    21961 acaaaatact acaagaatta acgtaaatag gtgctatgac aaaaggaaaa cgatttttta
    22021 agaatcataa ttttgaaaat taaaaaaatt aaaaatgcta ttgactgctt ttttttcaga
    22081 ttatataata aacacaaaat atttaaaatt taaattgaat taaaaagatt atatgaatgt
    22141 aaaaaaggag agtgatatat acagtatata aagcaataca cttaataaca aatcgaataa
    22201 tctaaaaaat cttaatattt taattattca gaataattaa ttttatcaag aaaaattaga
    22261 gaaaaaacaa aaaaccaact gtgtttaaag tatacaggtt gattttgttt aattaagaaa
    22321 gttgtattaa atattgtgaa gattttataa attatgaaac ataattgaca aatttaagtc
    22381 aaaaatgtat aattaaataa aatctcgtca aaaggttttc atttaatgaa gagattggac
    22441 ttatttttta gtaaaaggta gtaaaattca aatgggggtg ctttaaatgg gtgagaaaca
    22501 aatcaatttt aaagatgtaa ttgtaattgg atttgcacta tttgcaatgt tttttggtgc
    22561 agggaactta atcttccctc catatctagg agttttatct ggaagtagtt ggctaatagc
    22621 tttcatagga ttcctttttg cagatggtgg tttggcatta ttagcagtta tagcagcaac
    22681 taagttcaat ggagacacat cgaagatgtt ctcaagagca ggcaaaggat taagtattgc
    22741 attaggatgt gcaatggtaa tctgtatagg gccactttta gcaataccta gaacagcagc
    22801 aacaacttat gaaatgggta tattacctac aataggttct ggaataagcc cagtaatatt
    22861 ctctatagta ttctttgctc tagtattggt tttaacaata agaccatcaa aagttgtaga
    22921 tatagttggg tcaatattaa ctccagcttt acttatagct ttagcagtat taatagttaa
    22981 aggtatcata tctccattag gagaaataag agacagttct ttaatacaaa atgtatttgc
    23041 agaaggtata actcaaggtt atcaaacaat ggatgcattg gcagctagtg tatttgcatc
    23101 aattataatc atgtcagtaa tagctaaagg ttatacaggt gagaaagaaa agatgaaagc
    23161 cacaataagt gcaggtgtaa ttgcagtaat aggaatggca ttagtttatg gtggattatg
    23221 ttatcttgga gcaactgtgt ctcaacaata tggacaagat gttcaacaaa cagctttaat
    23281 agttgcaata acagcagctt tacttggaac tacaggtaaa attttattgg ctattatagt
    23341 tgcattagca tgtttaacaa cagctatagg tctttcttca gcagctggtc aatatttctc
    23401 aacacttaca gatggaaaat taaagtatga gcatatagtt atagtagttt gtgtatttag
    23461 tgcaatcata tcaaactttg gagtaagtac aataatacaa ttctcttctc ctatactaag
    23521 tatggtatat ccagcaacta taactctagt tatactagca ttatttagta ataaaattaa
    23581 aaatgacaac gtgttcaaat gtgctgcata catggcatta ttagtaagtg tattaacagt
    23641 tgcaacaagt tttggtgtaa aaattcctct agttaatagc ttaccatttg cttcattagg
    23701 atttaactgg atagttccag ttgtaatagc aggaataata ggaaacttta ttccatctaa
    23761 aagcagtaaa actgcataat aataaaaact aattgataat tatggaattg cctttaaatt
    23821 atataggcaa ttccttttta tatttaaaag aattattaaa ttattgtaga taaaagaaca
    23881 ttattaatcc tatttgataa atttaaaaat ttatttttgg agtagtatga tttataaaga
    23941 taataaaata aaaaagattc atttataatt ataaataaaa ttaaattata tattataaat
    24001 gtttagtatt aatataaaaa catcaataca tatttttgta aagaaaaaat aaagaattta
    24061 ttttctaaat acttattaat taatcaaagt taaaatgaaa aaaatataaa aaaataaagt
    24121 atataagagt ataatttgac ttttatatac ttttttatat tatttttgag ttttttagga
    24181 agatatttta caagttaaga aaactataag gagtgttata ttgaatataa aatagtataa
    24241 tatatattat gttagataat taatatgaaa atatacaaat atataaaaag tttgtttaga
    24301 gttatagtta atgtgtgtat taatttaata ctaatttatt ggaggtttaa aaatgaaata
    24361 cataataaaa agagatggta caaaagaact ttttagtaaa agtaagattg aagatgctgt
    24421 ctataaagct agtataaata gtgaaggtgg agtagataga gagttggcat atgatatatc
    24481 aagaaaaata gctaatgact ataattctat ggaaaaatgc ttatccgtag aagaaataca
    24541 agatatagtt gaagtactac ttatggaatc aaatagaaaa gatatagcaa aacactacat
    24601 attatataga gaaagacgct ctgaaataag gactaaagct tgggagtttg atgaattaca
    24661 aaaatcaata tggaagaaca agtatagaca taatggtgag agttttgatg aatggataaa
    24721 gagaatttca aataatagtt caagaatatc aaaactaata agacaaaaaa gatttctatt
    24781 tgctggaaga attttagcaa atagaggatt acagaaagaa ggaaaaaaag taacatattc
    24841 taattgttat gtaatagaac caccaaaaga tagcatagaa gatatatttg atactgcaaa
    24901 aaaacttgct agaactttta gttatggtgg aggagttgga attgatattt caaagctaag
    24961 accaaaagga gcgaaagtta acaatgctgc aaaacatacg actggagcag tctcttttat
    25021 ggaactttac agtatgacaa ctggcttaat tggtcaaaga gggagaagag gagctcttat
    25081 gatttctatg gatgtaaatc atccagagat agaagacttt atagatataa aaacagattt
    25141 ggagaaggtt actaaagcaa atatttctgt aagagtaaca gatgaattta tgcaagctgt
    25201 aagagaaaaa aagttatata attgtacttt tgaagttgaa actactggag aaaaaatagt
    25261 taagatagta aatgcttatg atttatttaa taaatttgtg aaaaataact gggattatgc
    25321 agaaccaggt atattgtttt gggataaaat aaaaacatat aattttatga gtgaagataa
    25381 gaacttttgc ttttcaggag taaatccttg tgcagaagaa ccacttccaa gtggaggaag
    25441 ttgtctactt ggctcaataa acttgtcaga gtttataata caaccatttg gtgaacatgc
    25501 tacttttgat attaataaat taaaatcttg cgttagagaa gctgtagtag ctttaaatga
    25561 tgtcttagat gagggattga acttgcatcc attacaagaa caaagagata gtgtacataa
    25621 gtatagacag ataggtttag gtgtaatggg tatagctgat atgcttataa aaatgggaat
    25681 aagatatggt tctgatgaat ctttagaact atgtgattta attggtaaga ctatgttaaa
    25741 tgaagctgtg aagcaatcag cactaattgc taaagaatat ggaacattta gtgagtataa
    25801 atatgaaaat atttctaaat ctaagttttt tatagaaaat ctaaatgaag acactaagga
    25861 aatggttaaa aagtatgggc ttagaaattc acaactttta accatacctc ctacaggttc
    25921 tatatctaca atgataggta ttagtggtgg aatagaacct atatttaatc tttcatatat
    25981 aagaaaaact gaaagcttgc atgatgagga tgtgtattat aaagtatata ctccaattgt
    26041 taaagagtat atggacaaga aaggtattac agatgaagaa tgtttaccag atttttttgt
    26101 tactgctatg aatataggat atgaagaaag aataaacatg caaaaagtat ggcaaaagta
    26161 tattgatgct tctatatcat ctacaataaa tatacctttt gaaactacag ttgaagatgt
    26221 tttcaatata tatattaagg catgggaggc tggtcttaaa ggagtaacaa tatttagaga
    26281 tggatgtaaa aggagtggaa ttttaataaa tgaaaaaaag gaagaaaata ataaagaaga
    26341 taaaaaagaa aatagtaaaa aagaatatta taaaaataat aaaaaagaaa aagataataa
    26401 agatgaaaaa gccaaagaaa taataaataa aaattttgaa gaagatgaaa aatttgtgtg
    26461 tcctgagtgt ggaagtgaag gaattgcaca tacaggtgga tgtagtatat gtttaaaatg
    26521 tggctatagt ggatgcaatt aaactctaat taaaaaattt taatatattt aaaaattaaa
    26581 tttttaaaaa cgaaagatga gggaatggta tgcaggataa aagtgtgagg gagattaaag
    26641 aaataataga gactttagaa gtagaaaaat atatggaata tatagagctg ttaagagttg
    26701 atgaaagaaa atctgtacaa ggtctagcta taaaactagc aaaaaagctg gataatatta
    26761 gaaaagaaga agaaagattg gaaactataa atatatttga gaacgaaggc tatgataaag
    26821 gttatttata tattggagga attgatgagg cgggaagagg accacttgct ggacctgttg
    26881 tagcttctgt tgtagtattt aaaaaagata ccaaaataga aggtgtaaat gactctaaga
    26941 aactgagtga ggcaaaaaga gatgaacttt ttgaagtaat aaaagaagaa gcactagatt
    27001 atggaatagg tatagtaaac aatgaagaaa tagatgaatt taatatatta aatgctacat
    27061 atatggcaat gaaaaaggct ataaattgtt taaaaaaagc accggattat ttattagttg
    27121 atgcagcaac aataccaggt attgacatat ctcaaaatcc aattgtgaaa ggagattcaa
    27181 aatctatatc aatagcagca gcaagtatac ttgctaaagt tactagggat agtataatgt
    27241 accaatatga tagagtatac ccagaatatg ggtttaaatc tcacaaagga tatggaacta
    27301 aagaacacta tgaagctatt gaaaaatatg gcataactcc tatccacaga aaaagttttt
    27361 tgaaaaatat actgtaaata taatatgata taatgtatat aatataaatt actatagtta
    27421 atgggggatt aaagatggaa tataatgaat tattaaaaag tgctagagaa aatttaaatg
    27481 gaagttgtaa agtttgtaag gtttgtaatg gggttgcttg tgcaggtgaa gtgcctggca
    27541 tgggaggtaa aggaagtggt tcttctttta tagaaaatag caagagttta gaaaaagtaa
    27601 aagtaaatat gagagtaata catgatgtat caaatcctga tacatctata gagatgtttg
    27661 gaaagaaaat gagtgcacct atatttgcag ctccagtaac aggaactact ttaaatatgg
    27721 gtggaaaaat taatgaaaga gattacatag aaccagtagt tgcaggatgt gctaatagtg
    27781 gtatttatgc aatggttggt gatacggcag tagatgcttt tttaatggaa aatttagatg
    27841 tagtcaaaaa gtataatgga gctggaattg tatttattaa accttgggat aatgaaaata
    27901 ttataaaaaa gataagatta gctgaagaag ctggtgcatt tgcagttgga gttgatatag
    27961 atgcctgtgg tctagtaact ttatcattac atggaaaacc agtacttcct aaaaatgtta
    28021 aacaaataaa ggagttagta aagtctacta aactaccatt tatattgaaa ggtataatga
    28081 ctgttgaaga tgctttaatg gcagtagaag caggtgtgga tgcaatagtt gtatcaaatc
    28141 atggaggaag agtgcttgac tgtacaccag gagcatgtga agttttacca aaaattgctg
    28201 atgctgttaa aggtaaagtt acaatacttg cagatggtgg agtgagaact ggtttagacg
    28261 tactaaaaat gataggttta ggtgcagatg cagtattaat aggaagacct tttgtgactg
    28321 cttcttttgg tggtgcaact gatggtgtag aaacttatgt aaataaactt caatcagagc
    28381 taagtagttc tatgatatta actggatgtc aaactataaa agatattgat ggaaaagtta
    28441 tatacaaata aaattttata caaaaaagag gaaaaatcat tttaatgtag aataattgta
    28501 caaaggggga atttatatga gtagaaaagc ttatgaagaa gccttagtag aattagaaaa
    28561 atttattgat gaaagaaaag aaataattaa aagtgcggag gactgtattg ataagtacat
    28621 agttgacaga acgctacctt ttgattacaa agataaatgt gtggaatggc aacaagagtt
    28681 acttgatatt gcagaggcac aagttttaga agcaaatgaa ttaagtgtat tattacaaga
    28741 gaaaaaagaa cttgaagaag attaaatttt attagctaag agtaaatcag taatatgatt
    28801 tactcttagt tttttttatt tgaataaaat acatctatct aattgagata actttattaa
    28861 tattagatta ggcagtttaa aataagctaa agtagcatgg atgattagta taaaaaataa
    28921 aaccagttta aaaaactggt ttaatttgta ttctttgaat ttaatatatg ttttttcatt
    28981 tcctctaata ccattgtata ggatttacat tgagcagcag ctaattctga taaagcaaat
    29041 ttttgagctt tatttaaaaa ctccttatct gtgctacaca attgttttga actgtcttgt
    29101 atcataagca ttttgattaa ttttacaatt tcaaaaacat ctcctgaatg aaatttatct
    29161 tggtacagtt taagtctttc ttttctatca aaaatccata caccatctgt tttattaata
    29221 gattggataa aattatcaac atcatttcca tccataactg gacgtatgcc aattctatct
    29281 gcatttagaa ctggaatcga aattttaagg ttactattaa aaatgacact taattcatag
    29341 tatttttgca tctcatgatt tattttcttt gttacaatat catttacaga gcaggctccc
    29401 tcttttggat acattacact ttcaccaatt ttatacatat gctagttata cctccaaatt
    29461 gaattttaga tattgcaact taggtacaat gctttaatta tctaatgatt aatattataa
    29521 cataaataac ttgacaagtc aaaaatatta atatataata taaggtttag acttggtgat
    29581 gtgtgaaact aaagagaaaa atataagata aaataattta atatgttgaa atattctttt
    29641 acaactatat aaaaatagat actaattata tttaataatt attagttttt agcaaaatct
    29701 cttagtttaa gacttcctgc agttacaaat ataattccaa ttaatattag agctattata
    29761 tttattaaaa tactaccatt gtttttaata gcatctatag tccaataaaa tggtgtgaac
    29821 tttgaaagat tagtcataaa ggataattta tccattgatg gtattagact agagatagat
    29881 atagctagac ctattaaaga ataaaatgta gatataagac ttatagaact ttcattttta
    29941 aatactctag ctacccaaaa tacaaatcca gtggaaacaa aactatttgc tagtacaatc
    30001 atcaatacat tcagactcaa attaaagtct tctataattg aaaaacataa tagagcaaaa
    30061 gtgtatacaa ttgattgaat aaaaaatagt cctaaaaata tactgaaaat tatttttata
    30121 tctttattat ctgtagagat aagtcttttt agcacatttg atttttttaa tgtaaataaa
    30181 tcagaagcaa gatgtgctgc attaatatac ataaaatagc atatcaagaa gactactaaa
    30241 aatgaacctt tattcttatc tggtttgtta tcaattatat ttgtctttgt caatttatca
    30301 tctatatttt tatccacttt caattttaac gatttagtaa taaaagattc tatttgtgat
    30361 tctgcccaaa gactaccacc accattttca attttaaagc atttaactac aggtcgttgt
    30421 aatttatcta tactatttga aaaattttta tctaaaacga atacagcaga aaccttatta
    30481 ttttttaata gattcatagc cttatctagt tcatttaatc taaatgaatt ttcttttaat
    30541 ttagaactat ttattaactt atgttcatac tttcctgaag agtcagatac aattgctact
    30601 ggagaaaagt acattgattg atttcctgag ttgttgataa aaaaattaag tgaaaaaatt
    30661 agtataatag gaagcataac catattaatt aaaagattat gattttttag atatcttttt
    30721 atatttgcaa tagttaatct aatcattatt aaacctccct ccatttatat ttttccttta
    30781 caatagcaag tgcaattaat attgtagaga taattaaaca tgtgaaaatt aaatctccta
    30841 ttgaatctat agttttaaat gtttcataat tactaaacaa ttctcctatt aaataggtag
    30901 gagataaact tgtaagctta gtaaatgtat cacttatcat actgaagata cctccaaaaa
    30961 ttgtctgtaa aaagagtaat gcataaacta ttgctgtacc gtatttttta ctaaaaaagc
    31021 tggttacaaa ggtagatatt gaagtcataa aataagatga taaagcacaa agtaggagca
    31081 atatggcaaa attaccttta aatgttattc caagtattct aaagaataaa acatataata
    31141 ataagaatat aaatgaataa atccataaac ctacaaagtc ataaattaag aattgtactc
    31201 tagttatagg catagaataa agtctttttg aaagtccctt tgattcactt atataatttg
    31261 acaaaatatt gttcattata aaaattatta caagaaatcc tagtgaaact aaagcaaagt
    31321 attcataaga gttctgttta acattgttat ttattataga agtatcaata gaatttttat
    31381 taaataattt agaaaaatct tctgaactta ttttctgaga attatttaaa taaaattttt
    31441 catggtaagt atctaatata tcttgaagca atattgcaat atcatcacga gttccaagtt
    31501 tttctatgtt tagagtattt gatttttcat ttaataaact actctcatag cctttaggta
    31561 tagtaagctt taattctgcc ttagaatcat cttttttaac tgttaatata taagataaat
    31621 catttttcaa atactttgtc aaatcatttg ataatcttgt gttatctttg tcatatataa
    31681 caatgggggt agattctgtt tttatagggt tttgaaacat gctttctgta accatcccaa
    31741 gaaaccaaga taaaatcaga ggcaaagcta aaaaatatat taaattaagt ataaaggagc
    31801 tttttaaact ctttagcata gtttttacac tcatgtataa tttcataaaa tcacctccat
    31861 tagtccctta aattttttcc tgttagattt aaaaatacgt cttctaggct aggttcttca
    31921 taagaaattt tcattatttt tgaattgttt ttgtcaataa cagagagtat atctgtaagt
    31981 tgtaattttt tatctatatc caattctaat aatgaattat tttctaaaac agatataaca
    32041 cctttagtat tttttaaatc aaagataagt tgggcattta tattttttat ttctataatt
    32101 aattttgtat ttgtagatac gagtgatttt aaataatcat tatctccaaa agcaatttct
    32161 ttaccttcat ccataataaa aattttagaa caaaggtgtt caacttcttc catataatgg
    32221 gaagtatata ttacagtagt ttcatgtttt ttagatatat cttttataaa attgaaaata
    32281 tgatttcttg attgggggtc tacacctaca gttggttcat ccaatattaa tattttagga
    32341 tgatttaaga gtgctattcc aatatttaat ctcctttgca taccaccaga taattttttg
    32401 acctttttct ttttgacttc agtaagacct gtaacttcta atgcttcaat gattctttct
    32461 ttaagtagtt ttccctttaa accgtagaaa gctccaaagt actctaagtt atcaaaagga
    32521 gtaagagttt ctataattgc taattcttgt ggaactaacc ctattataga ctttgctttt
    32581 atataatctt ttgataaatc taaaccattg atttgaatac taccactatt tggtaacata
    32641 agatttgtaa ttatatttat aagtgtagat ttacctgcac catttgggcc aataagtcca
    32701 aatatctcac cttttttaac agaaaagctg atgttatcaa gtactaattt atcattaaat
    32761 ctttttgtta tattatttac tctgactata tccatagtaa tccctccaaa ataattttgt
    32821 ataagttaaa aagctataat attataataa agaattgtga attataattc tattactata
    32881 agtcactaaa aaaagtgact taagtcactt tatattttta gatttattct attacaattt
    32941 tatttttgaa agcaaagatt gctagttgag ttctgtcacg aagttctagt ttagctaaaa
    33001 tattagttat attattcttt attgtacctt cagataagaa tagttcttga cttatttctt
    33061 tattattaag tccatttgca attagtctaa ttatagatat ttctttttct gttaaattgt
    33121 acatgtcata aagatgctct tgtttaaccg ttttttcaga ggtcatgatt ttttcagcta
    33181 cacttttatc aagcacaata ttgccaaaaa atgaagaacg aatcccttca tgcaatactt
    33241 catcagagct atcttttaaa aggtatcctg aagcaccaaa cttcatagca tcttttatat
    33301 attcatcatc attaaaagtt gttaaaatta ataatgttat agaattatta tattccttta
    33361 taagccttgt acctagaacc ccatcacata ctttcattcg tatatccata agaactatgt
    33421 ctacatcatt cattttacaa aattctaaag cttcatatcc attagaagca tctcctacaa
    33481 tttctaaatc attataagat gataatataa ttttaagacc ttttctaatt aatttttcgt
    33541 catctactat aagaacttta attttattca aaaaaatcac cccctgaaaa tttaggaaaa
    33601 gaagctctaa ttgtgaaacc attattagaa ttatcaaatt caactttacc atttaattca
    33661 tatattctct cattgatact attaagtcca tttccttttt ttatattgcc acatcctata
    33721 ccattatcac taatagtaat tataagattt gaagtattga atgtaataaa aattctgatt
    33781 tcagttgcct ttccatgcct agatgagttg gaaagggatt cctgtataag tctatataaa
    33841 gttatagatt gatttctgga taagttccaa gtattttttg aaatagttaa tttaacatta
    33901 atatttgtaa gcttaataaa gcttttaact aattctttga ttttaaataa actttggtaa
    33961 ttttcatatt caacaggttt taactcagat atagcccttc ttacatcttg aaaactttca
    34021 gttacaaatt ctctaagttc atgtactaag tcataaatta gaggtttgtc ttttaagagt
    34081 ttttctatag catttaattg tattattgtt gtagaaagag aatgtcctac actatcatgt
    34141 atttctcttg atattcgatt tctttctttt aaaattgcta attcttctat agaacttgca
    34201 taagtttcca aatcagcatt aacttttttt aattcatctt tagaaattct aagcttatca
    34261 taaagatttt gactgtataa ttttgataaa ttctcatttt ctatatatat agaaagtaca
    34321 gttataatta gcaatataga gcttgactcc agtgccaaat atatattttt atctaaacta
    34381 ataataagag
//
LOCUS       DAEPKC010000035        33680 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.035, whole genome shotgun sequence.
ACCESSION   DAEPKC010000035 DAEPKC010000000
VERSION     DAEPKC010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 33680)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33680)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33680
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.035"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            416..1723
                     /locus_tag="KR294_001734"
     CDS             416..1723
                     /locus_tag="KR294_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine dehydratase subunit alpha family protein"
                     /protein_id="HBH0239814.1"
                     /translation="MRDIRKELVEMLKAEVKPAVGCTEPVALALACAKAKELLGEEIV
                     ENRMLVSPSIYKNGMCVGIPGTERLGLKIAAALGIVGGHSENGLSVLETLTKEEVKIA
                     EDYMDNTPLSITPADTREKVFIEVVLKGKNHIAKVRIRTKHDNFTFLEKDGEVLLDNE
                     PKVSASNDAAEKAESLMDTVTIQELIKNVEGIDFKDIEFLLDGVKMNEEMAEYGLKQK
                     TGIGVGYGIKKSIEEGLLGNDVINYAMMLTAGASDARMAGVKMPVMSSNGSGNHGLTA
                     ILPIVAYNKKFPQSDERLAKALAISHLVTGYIKNYTGRLSAVCGCGVAASTGATAGIS
                     WLMNGTEKQIEGAIENMIADLSGMICDGAKAGCALKLSSAASAAIQSAIIAKQDCFVP
                     PLNGIVGSSVEQSIQNLGRVSDKGMSITDEIILNVMNDMNKVD"
     gene            2051..2590
                     /gene="hpt"
                     /locus_tag="KR294_001735"
     CDS             2051..2590
                     /gene="hpt"
                     /locus_tag="KR294_001735"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HBH0239815.1"
                     /translation="MDIETKKWEVLYSEEKIKDKLRELGAIIEKDYKDKNLMVVSLLK
                     GSFIFCADLVRNINLPLRVNFMTTSSYGNNEESTGKVKVVSDVTTDIAGYDVLVVDDI
                     TDSALTMDFVLKHLKAKNPASLKCCVLLDKPSRRKVDLVPDYCGFEIEDKFVVGYGFD
                     FGDYYRNVPYIFNVTDEDR"
     gene            2968..4644
                     /gene="bclA2"
                     /locus_tag="KR294_001736"
     CDS             2968..4644
                     /gene="bclA2"
                     /locus_tag="KR294_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like exosporium glycoprotein BclA2"
                     /protein_id="HBH0239816.1"
                     /translation="MSDISGPSLYQDVGPTGPTGATGPTGPTGPRGVTGATGANGITG
                     PTGNTGATGANGITGPTGNMGATGPNGTTGSTGPTGNTGATGANGITGPTGNTGATGA
                     NGITGPTGNKGATGANGITGSTGPTGNTGATGANGITGPTGNTGATGATGPTGLTGAT
                     GATGANGITGPTGNTGATGANGVTGATGPTGNTGATGPTGSIGATGATGTTGATGPIG
                     ATGATGADGEVGPTGAVGATGPDGLVGPTGPTGPTGATGANGLVGPTGPTGATGANGL
                     VGPTGATGATGVAGAIGPTGAVGATGPTGADGAVGPTGATGATGANGATGPTGAVGAT
                     GANGVAGPIGPTGPTGENGVAGATGATGATGANGATGPTGAVGATGANGVAGAIGPTG
                     PTGANGATGATGATGATGANGATGPTGATGATGVLAANNAQFTVSSSSLVNNTLVTFN
                     SSFINGTNITFPTSSTINLAVGGIYNVSFGIRATLSLAGFMSITTNFNGVTQNNFIAK
                     AVNTLTSSDVSVSLSFLVDARAAAVTLSFTFGSGTTGTSAAGYVSVYRIQ"
     gene            complement(5227..5982)
                     /locus_tag="KR294_001737"
     CDS             complement(5227..5982)
                     /locus_tag="KR294_001737"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HBH0239817.1"
                     /translation="MLKVIISGYNGTMGRVLAECVKKDNELELVCGVARSADEKGHHS
                     DTKLYKTMTDVTEKTDVIIDFSHHDTLEPILSYALKNNTPVVLATTGYDENDLNKIEE
                     ASKNIPILLSSNTSLGVNILIKLVKDASKMLEGFDIEIIEKHHNRKEDAPSGTATMIA
                     NAIREVLPESENTHGRYGRDCKRKPNEIGIHSIRGGNIISDHDVVFAGDNEVLTLSHH
                     SQSDEVFANGSIVAAKFLIGKQSGLYKMSDILG"
     gene            6422..7411
                     /locus_tag="KR294_001738"
     CDS             6422..7411
                     /locus_tag="KR294_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HBH0239818.1"
                     /translation="MLKEEKTYQEKDAKVFNGVAALIMILLFLVVSIGIMVFGIVKLD
                     SGFTGIGSLMLILGLVFIVVDFILFFGLKMINPKEAIVLVLFGNYYGTIKKEGYYWVN
                     PFCSAINPAVSRINVSKSSSDEKVDISTNSRGKKVSLKTMTLNNEKQKVNDLLGNPII
                     IGVVVIWKVIDATKAVFNVDNYNTFLSIQCDSTIRNVSRLYPYDVSEDGDEKSLRGSS
                     QEIADRLKDELQSRVDIAGIEVCEVRITHLSYAPEIAAAMLQRQQAEAIIAARKKIVE
                     GAVSMVEMALTNLSENNVVTLDEERKAAMVSNLLVVLCGNKDAQPVVNSSSIY"
     gene            complement(7863..8579)
                     /gene="dapD"
                     /locus_tag="KR294_001739"
     CDS             complement(7863..8579)
                     /gene="dapD"
                     /locus_tag="KR294_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HBH0239819.1"
                     /translation="MVNLNDAYEIARYIKEVKKKTPVKVYVNTNSLHFQSTDKFKVFG
                     SNGSYIFVGDYEDIMEVLDKHGNDITDTHVEYDRRNSAIPLKNTLSEHARIEPGAIIR
                     DMVTIEKNAVVMMGAVINIGAVIGEGSMVDMNAVIGARGTLGKNVHLGAGAVVAGVLE
                     PPSATPVIVEDDVLIGANAVILEGVRIGKGAVVAAGAVVTTDVEAGAVVAGSPAKVIK
                     MKDEKTADKTKLMEDLRNLD"
     gene            complement(8803..9552)
                     /locus_tag="KR294_001740"
     CDS             complement(8803..9552)
                     /locus_tag="KR294_001740"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HBH0239820.1"
                     /translation="MLKVIATGYDGKMGKILADTIREDNELELVCVAARGLDSYEGDL
                     KIYEDMSTIVEEADVVIDFSHHSNLDNILSYVLKTKTPLVIATTGYNDDEMNKIREAA
                     KVIPVFQSYNMSLGVNVLVKLVKDAAKLLEGFDIEIIEKHHNRKVDAPSGTAVMIANA
                     IKEVLPNVENNYGRYGRSAKRQPNEVGIHAIRGGNIVGEHDALFAGDNEVLTISHQAQ
                     SRGIFASGSIAAAKYLVKQKPGFYNMDSMLG"
     gene            complement(9619..10506)
                     /locus_tag="KR294_001741"
     CDS             complement(9619..10506)
                     /locus_tag="KR294_001741"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HBH0239821.1"
                     /translation="MIFKGSAVALVTPFTKDNKVDFDKLGELVEYQIANGTDAIVSCG
                     TTGEANTMTDEEQLATIKYVVEKVNKRVPVIAGSGSNDTMHSVNLSQEAEKLGVDALL
                     IITPYYNKANKAGLKRHFETIANSVKLPIILYNVPGRTCVNISPSLIVELAKIDNIVA
                     VKEASGDLGQVAEIASLVPDDFAIYSGNDDTILPLLSLGGQGVISVLANVCPQETHDL
                     VAKFFEGDIEGSRKLQLGMDALIAALFIEVNPIPVKTAMNLLGFNVGDLRLPLAEMDP
                     ANLEVLKKELVNFGLKVNA"
     gene            complement(10623..11624)
                     /locus_tag="KR294_001742"
     CDS             complement(10623..11624)
                     /locus_tag="KR294_001742"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HBH0239822.1"
                     /translation="MKKVNVAIIGATGMVGRTFLKVLEERNFPIENLFLFSSSKSAGS
                     KVMFCGKEYIVEELKETSFTDRGIQIALFSAGGSISEKYAPIAASNGILVVDNSSQWR
                     MNPDVPLVVPEVNPEAIKNHKGIIANPNCSTIQAMVPLKALDDKYKIKRVVYSTYQAV
                     SGSGVKGVEDLEKGMNGNPTGFYPHQISYNCLPHIDSFTENGYTKEEMKMVNETMKIL
                     DNYDLKITATTVRVPVKNGHSESINVEFNNPFELDDLVKTLEEAPGVVVVDNPAKNEY
                     PTAVEFDDRDEVFVGRIRRDFSVDNGVNLWVVADNIRKGAATNAIQIAEMALSYDLV"
     gene            complement(12049..12930)
                     /locus_tag="KR294_001743"
     CDS             complement(12049..12930)
                     /locus_tag="KR294_001743"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HBH0239823.1"
                     /translation="MLFKGSAVALVTPFTEDNNVNFEKLGELIEYHIENGTDALVVCG
                     TTGEATTMSESEIFAVIKYTVEKVNKRIPVIAGTGSNNTMLSVHMSQEAEKLGVDGLL
                     IITPYYNKTNEKGLKLHFETIANSVKLPIILYNVPGRTKVNIKPSVVAELAKIDNIVA
                     VKEASGDLAQVAEIAKLVPKDFAIYSGNDDTILPLLSLGGSGIISVLANICPKETHDL
                     VTKFFEGDIEGSKKLQLDMDALIAALFIEVNPVPVKTAMNILGFNVGDLRLPLAEMEE
                     TNLNVLKQELTNFGFKF"
     gene            13253..14446
                     /locus_tag="KR294_001744"
     CDS             13253..14446
                     /locus_tag="KR294_001744"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase"
                     /protein_id="HBH0239824.1"
                     /translation="MDTLKELFKIGSGPSSSHTMGPQRAAERFKNENPDAESFRAILY
                     GSLAATGKGHLTDYIIEKTIAPKKVEIVWEEDIIKDFHPNGMKFEALDKDKNVTAEWT
                     VYSVGGGTIAEEGQRNSKSNSIYHLDTMDEIVKWCKENNKTLVDFVLECEPKDIKDYI
                     KTIKDAMRKSIDDGLSTDEIIPGKLLLKRRASTFYNAYKKDKSFSTLVYAYALAASEQ
                     NASGNIIVTAPTCGSAGVIPGIFFAMQDFYNYDDEKIIEALLVAGIIGNIIKTNASIS
                     GAEVGCQGEVGAACSMAAAAVAYLKGGTIDHIEYAAEIALEHHLGMTCDPVYGYVQIP
                     CIERNAMAAQRAYDAANYALLTDGSHSVSLDQVVETMKETGIDMMDKYKETAKGGLAK
                     HFFSC"
     gene            14652..15770
                     /locus_tag="KR294_001745"
     CDS             14652..15770
                     /locus_tag="KR294_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HBH0239825.1"
                     /translation="MREASYLQEQLYKHRKSLNPIAEIGRKEYKTSKYIRDYLDKLGI
                     EYEVYLETGIVGVIEGKRPKKDIAFRADIDGLHSEEGVKHLCGHDGHATILLGLIEYL
                     NDNKEDLNDNIVFIFQPAEEGPGGAKALIDEGVLRKYNIDEIYGLHIYPELPEGYVGT
                     REGYFMAQIGDIDIEIVSKSGHGAMPQNGIDGIVIASNFVSSLQTIVSRNISPIDNAV
                     LTIGRIEGGARRNIIAENIKMEGTMRCFSPEVYEKMKLRVRELARGFELAYNCKVNIN
                     IIDDYIAVKNDKDLYQEFVEAIGSDTVVELEPLMISEDFSYYQKEVPGLFFMLGSRNE
                     EKGFVNGLHNINFNFDEKICVNALNVYSKLLKYKEAID"
     gene            15901..16146
                     /locus_tag="KR294_001746"
     CDS             15901..16146
                     /locus_tag="KR294_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small, acid-soluble spore protein, alpha/beta
                     type"
                     /protein_id="HBH0239826.1"
                     /translation="MKEKVQREKKITNGKNTKILTNDDIMKYEIASELGLMDKVGERG
                     WAGLTAKEAGRIGGMLTSRKKRLKKIVEEQNKKDESI"
     gene            16133..16879
                     /locus_tag="KR294_001747"
     CDS             16133..16879
                     /locus_tag="KR294_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBH0239827.1"
                     /translation="MSQYSDFAFVYDELMNEVDYNGWVKYIEDIIDSEGVKVKNILEL
                     ACGTGNLTIPLTKKNYDIAGIDISDEMLSVAREKSEKEGVELVLLQQDISELDFEISD
                     LDCVLCACDGFNYITYDDDLENVFSKTYELLKKDGIFIFDISSFYKLANILGNNMYGE
                     NREDIAYMWQNYFDEEENLIEMELTFFIKDECGKFERFEEIHQQRAYTEDEIVDMLEK
                     SGFKDIKYYGDFTFDKPSEESQRIFFVCKK"
     gene            17164..18039
                     /gene="hslO"
                     /locus_tag="KR294_001748"
     CDS             17164..18039
                     /gene="hslO"
                     /locus_tag="KR294_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HBH0239828.1"
                     /translation="MRDYVLRATSGNGQVRAFVATTRNTVEEARRLHETTKVATAALG
                     RTLTATSIMGLMMKNDSDKLTVIIKGGGPIGTIIATSDSKGMVKGYVGNPQVEVEDYP
                     NGKLNVAAAVGTEGVVKVIKDLGLREPYNGTYPLVSGEIAEDFTYYFAVSEQTPSVVA
                     LGVLTKEDEVEFAGGFIVQLMPDAEEETIAKLEENVAKLPSITNMLKEGKSPEDILNI
                     VLDGLEPKILDTCEVGFMCECSKERVKTALVAIGKKSLAQIIEEDKKAEVGCQFCNKK
                     YMYSEEELLEILKEM"
     gene            18430..19230
                     /locus_tag="KR294_001749"
     CDS             18430..19230
                     /locus_tag="KR294_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HBH0239829.1"
                     /translation="MESKTKYIGISILILLMIFLIAKNFNGKLEIPIPESNSRKFKSA
                     AVFYPQHQDDEVLWGGSAIVDAIKQCGVDNVYVVLVSDGSGVNVFKANTKFRNLTRKQ
                     KEELRNNEFKSALRELGVKPQNVIILADIDKKEGTHYELMEKTILDFEHKFKGNVTHI
                     AHHYKYDDHIMHRKNGEVLKKLKREGKIKDDLYFVKPKYVKYIPRNERAIYKAMDFDD
                     YNKVKSACYEYKVVNSKRKMYGIGYISAHSYFEHLLNDPELTSVLSED"
     gene            19757..21997
                     /locus_tag="KR294_001750"
     CDS             19757..21997
                     /locus_tag="KR294_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HBH0239830.1"
                     /translation="MNNEFIILKGCKENNLNNISLKIPKRKITIFTGVSGSGKSSIVF
                     ETIAKESQRQLNERFSTFVRSFLPKYGEVKADCIENLSTPIIIDQSRLGGNSRSTLGT
                     ITDVNSFLRALYSRFGSEYIGNANMFSFNNIDGMCPHCHGLGKKLVPNMNQILDMNKS
                     LNEGAILLSGFGVGSWHWNIFAESGFFDINKRICDYSEVELEKFLHGKAEKIKIENAG
                     QTNMTYEGLMVKFNRLYLSREGEISEATKKKLSKLLIEDRCPICDGRRLNERVYRSLI
                     NGYNIADLTSMQIDELAEVIKSIDEPEAQPLIKGIIEKLNSIIDIGLGYLTLDRETSS
                     LSGGESQRIKMVKYLNSNLVDLMYIFDEPSVGLHPKDVYKLNNLLKKLRDKGNTIIVV
                     EHDPDVIKIADHIVDVGPKAGKYGGEVVYEGSYENLLTSGTLTGNALSKFLPIKESVR
                     EHSGYLEVKNCNKNNLKNVSIKIPKGVLTLVTGVAGAGKSTLIKDEFLKQNPSAVLID
                     QSPVSANSRSSLATYSGIMNNIRSIFSKTNGVNASLFSSNSEGACDNCKGSGIVEMNL
                     AFMESIKSTCNVCEGKKFKKEVLEYRFQGKNIIEVLEMSVLEAIEFFNLKQIKTKLQC
                     IEKMGIGYLTLGQTLDTLSGGECQRLKLASELNKESSVYILDEPTTGLHMADIENFIS
                     IIEEIVDNGNTVIIIEHNIDVIKRADWIIELGPEGGTKGGRVIFEGIPKQLCNNKISL
                     TAKYIV"
     gene            22411..23946
                     /locus_tag="KR294_001751"
     CDS             22411..23946
                     /locus_tag="KR294_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBH0239831.1"
                     /translation="MINDILTLLSERSDFFIKLSIEHLMISIISIIIAIVLGGIIGII
                     VSEFHNSSKPILGTINFLYTIPSISMLGFLIPFSGIGNTTAVIALTIYALLPMVRNTY
                     TGITNVDKNILEAARGMGSTDFQILYKIKLPLALPVIMSGIRNMVIMTIALAGIASFI
                     GAGGLGVAIYRGITTNNTIMTITGSILIALLALIFDFILGLVEKFFQRKRKKKNRKKV
                     FAILGSLILIATIFTSYLFNPSKTQTIHIATKPMTEQYILGEMLDILIEKNTGLNVEI
                     TQGVGGGTSNIQPAMENGEFDIYPEYTGTGWNMVLKKNELYTESMFSKLQSEYKTKLK
                     MQWTGMYGFSNSYALAVRKEVADKYNLKNITDLKDVSSKLTFGAEYDFYEREDGYTPL
                     CNTYGLNFKDTVDLDIGLKYQAINEGKIDVMPIFTTDGQYSVSDVVVLKDDKNFYPSY
                     QCGNVVRLEVLEENPELSKVFKMVGDILTDKEMAKMNYDVENNNLEPREVAREFLNKK
                     GLL"
     gene            23962..24723
                     /locus_tag="KR294_001752"
     CDS             23962..24723
                     /locus_tag="KR294_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0239832.1"
                     /translation="MTPIIQFKNIKKQYNDKTIIDNLNLDIEKGEFLTVIGSSGSGKT
                     TLLKMINGLILPDGGNILINQTDIKNEDLIKLRRRIGYCVQGSVLFPHMTVEENISYV
                     PNLLSKKNKLEVKSAVNKWMEIVGLPNDMKVRYPSELSGGQQQRVGIARALASSPEIL
                     LMDEPFGAVDEITRKQLQKEIKEIHKKTGVTIIFITHDIYEALILGTKTLVLNHGVVQ
                     QYDTPENILNTPANQFVDQLLNIRKSIIDDDNLKE"
     gene            25061..25930
                     /locus_tag="KR294_001753"
     CDS             25061..25930
                     /locus_tag="KR294_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBH0239833.1"
                     /translation="MDNNLITIEKTLDYIEKHLLDEMLDLNVISKEIGYSKYHLHRMF
                     TSVVGFSVHNYIQRRRLTEAARMLIFTEKPIIEIALISGYDTQRSFSRGFKKMFKRSP
                     NFFRRHQDFLPLQLKFDIHNRKKLRGDMVLDVKKVNCADINIVGYSGKVRKGFHIIGK
                     CWRDLHKNKEMIENKVDLGFLIGVSDYSNFKEIENTPTFTYIAGAQVATFGKLPNGME
                     KFVLPKSNYIVFTFIGKNEDSMQNVVEYIYQEWFPNSSCQFNENNLYDFVKYGEKTDE
                     NGLSEIQFWVPII"
     gene            26259..26510
                     /locus_tag="KR294_001754"
     CDS             26259..26510
                     /locus_tag="KR294_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3781 domain-containing protein"
                     /protein_id="HBH0239834.1"
                     /translation="MNVENELLKNLDRLHTTELGVVRIKKNLSLETNDVVNWCKTKIE
                     SPNAIINRKGKNWYISVYDCIITVNAHSYTIITAHKEKK"
     gene            26622..27401
                     /locus_tag="KR294_001755"
     CDS             26622..27401
                     /locus_tag="KR294_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBH0239835.1"
                     /translation="MNDTVKEKLAESLTSDTTDILPYLPYLLQDFWELGSSPEQMLQL
                     FRKHIPFNEDTKVLDLACGKGAVSVKLAKELNIHIKGIDLIPEFIDYARRKAIEYKVD
                     ALCDFEMNDANSSVKIEHDYDCVIFGAVGDILGNYKETISKLLPTIKSKGFILIDDAY
                     VVDKSTNEQLNFERVYPTYNEWCILFKELGLKLIECIPCLELENDVEEEMNWIITRAN
                     ELIKKYPSQKDMFEQYVISQKNEYTDLQQDLVGATWILQKE"
     gene            complement(27536..28186)
                     /locus_tag="KR294_001756"
     CDS             complement(27536..28186)
                     /locus_tag="KR294_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239836.1"
                     /translation="MNIVMINGSPKVNKNNSQYFLSELKQLIQNDNKVFTFKVDNTSK
                     YPDALNAILNCDRLIIASPLYVDGIPSHLLHFLEKCEKFLKTQNKKPIPVYAIVNCGF
                     NEGEHNHLAIQMIEHWCKKINFTWVQGIGIGAGEMFGSLESVPLGKGPKKDLGIALKE
                     LSKNILSDNIHIDDSNKSTIFISPNFPRFLYKLMGNHQWNTQAKSNGLTKSDILKK"
     gene            complement(28183..28686)
                     /locus_tag="KR294_001757"
     CDS             complement(28183..28686)
                     /locus_tag="KR294_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBH0239837.1"
                     /translation="MRLLIHDLTDKELEKLLPKLDDNIKILPNTKEIHKCIGCFGCWI
                     KTPSECVVKDYYSNMGKLINDSDGIIIISRCCYGGFSPFVKNVLDKSINYILPYFVIK
                     DNMMRHKSRYDKQINLKAIFYGDCITEAEKETATKLVNGNAINFNIKEHSVCFYENIQ
                     DIRGESI"
     gene            complement(28735..29250)
                     /locus_tag="KR294_001758"
     CDS             complement(28735..29250)
                     /locus_tag="KR294_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBH0239838.1"
                     /translation="MLEYIILGFLMEKELSGYDLKQIMSESTSYFFDASFGSIYPALK
                     RLETKGYIHYHEVIDGNKLKKLYSITNTGKEVFLEWLKKPINFSKTKQDHLVNIFFYK
                     YLPKEIIETNLKMLITEVELLLNKLSKQKNDAEENHCVDQYTYMYATMIYGVDYYNFV
                     INWCKDLLKNL"
     gene            29530..30054
                     /locus_tag="KR294_001759"
     CDS             29530..30054
                     /locus_tag="KR294_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBH0239839.1"
                     /translation="MHEQIDCCERKKRTIDIKGENMRELLKWVSIINRYNTNYIDRKL
                     ADIGINNSQYFYVLHICNNPGITQDTIFEKILVNPSNITRALANLEKEGFITREPGVK
                     DKRTWHLYPTEKSLGCYDEILKITNGYVEELLSSFEKEEQELFMSMLKKVAFLAIDMN
                     EEAKLEAKENGRKI"
     gene            30038..31441
                     /locus_tag="KR294_001760"
     CDS             30038..31441
                     /locus_tag="KR294_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBH0239840.1"
                     /translation="MEEKYKEPLEYEKVSKLLTKYAIPSIIAMLVSALYNIVDQIFIG
                     QGVGVLGNAATNVTFPLTTICTAIALLLGIGGASKCSLELGAKNSEKATKAAGNSICL
                     MAVFGISLFIVVSIFLTPLLKFFGSTSEILPYAHTYTKITSIGLPFLIMSTGMSKLIL
                     ADGRPKASMFCMLIGAVINTILNPLFIFVFNMGIAGSALATVIGQLISFGISVHYIKN
                     FQHIKLHKKSFKLDSIIYKHIFALGSSSCFNQLAMTVTQIVMNNTLAYYGARSVYGSE
                     IPLACVGIIIKVNMIFISIIIGISQGMQPIIGYNYGAEKYNRVKEAYKFAVGSATIIS
                     VIAFLCFQLFPRQITSIFGNGNETYFIFAEHYFRTFLFLTFINGVQIVSSTFFTSIGK
                     SVLGLFTSLTRQILFLIPLIVILPMFMGIDGVMFAGPIADAAAAMVCIYFAVHEMKSL
                     TIKQNNLMSNHNKIAEV"
     gene            complement(32005..32316)
                     /locus_tag="KR294_001761"
     CDS             complement(32005..32316)
                     /locus_tag="KR294_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239841.1"
                     /translation="MKKIIKSFTFWFFLIALFEIYMHQIGQDSKSIVLIGLNPILSII
                     SRVDSFFVFMDSGMQIPCRTITGSISIYWYIASILSFLIYGIILDLIRIVISKIGNKT
                     K"
     gene            complement(32372..32965)
                     /locus_tag="KR294_001762"
     CDS             complement(32372..32965)
                     /locus_tag="KR294_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBH0239842.1"
                     /translation="MISDSISKRRSIRKYKNQSISHETIEKIIEAGINAPSSKNRQPW
                     RFVVITEKEKESMLKAMSKGIQNEINDNGLLPGSRQHIAGANYTVEIMKQAPVTIFIL
                     NILGKSPLEKLSPEERFYEMANMQSIGAAIQNMSLTAVELGLGSLWICDVYFAYRELC
                     EWLNTDSQLVAAISLGYPDEEPSRRPRLQLSDVTEWR"
BASE COUNT        12619 a         4115 c         5726 g        11220 t
ORIGIN      
        1 aaaaagctat ataaaattta aatttttcta aattcataac tttaaagaaa gctttaaact
       61 tatactataa gtgttttgca gaatcttttt ttatgaatta aaaaatggtt tttataagtt
      121 aaaaaataat atatttgagc cgtctcaaaa tgatatagaa tctcattttg agactttttt
      181 ttgtcttttt gcgaaattgt catatgtttc tccattttaa agaatataaa tactctatac
      241 aaataaaaaa aatacataaa tagaggcagt cataccaatg gttatagaat ataagactaa
      301 aaatataaaa agatataaaa aatatggcat gtattttgct ataaatatag ataagaaatt
      361 atttaattaa ttatttgagt actaaatcta aacttaattg ggaggtttat atataatgag
      421 agatataaga aaagaattag tggaaatgtt aaaggcagaa gttaaaccag cagtagggtg
      481 tactgaacca gtagccttag ctctagcatg tgcaaaggca aaggaattat taggagaaga
      541 aatagttgaa aatcgtatgt tagttagtcc tagtatttat aaaaatggta tgtgcgtagg
      601 tataccaggt actgaaagat taggattaaa aattgcagca gctctaggta tagtaggtgg
      661 acattctgaa aatggattaa gtgtgttaga aactctaaca aaagaggaag ttaaaatagc
      721 tgaggattat atggataata ctccactatc aataacacct gctgatacaa gagagaaagt
      781 atttatagaa gttgtgttaa aaggaaaaaa tcatattgct aaagtgagaa taagaactaa
      841 acatgataat tttacgttct tagaaaaaga tggagaagta ttattagaca atgaaccaaa
      901 agtatcagct tcaaatgatg cggcagaaaa agctgaaagt ttaatggata cagtaactat
      961 acaagaatta ataaaaaatg tagaaggaat tgattttaaa gatatagaat ttttactaga
     1021 tggagtaaaa atgaatgaag agatggctga atatggatta aaacaaaaaa ctggtattgg
     1081 tgtaggatat ggaattaaaa agtctataga agaaggtctt ttaggtaatg atgttataaa
     1141 ttatgcaatg atgttaactg ctggagcttc agatgcaaga atggcagggg taaaaatgcc
     1201 tgttatgagt tcaaatggaa gtggaaatca tggattaaca gcaattcttc caatcgttgc
     1261 ttataataaa aaattcccac aatctgatga aagactagca aaagctttag ctatatctca
     1321 tctagtaact ggttatatta agaactatac aggaagatta tctgctgtat gtggatgtgg
     1381 tgttgctgct tctactggag caactgctgg tatctcttgg cttatgaatg gtactgaaaa
     1441 gcaaatagaa ggagctatag aaaatatgat agctgactta agtggaatga tatgtgacgg
     1501 tgcgaaagct ggttgtgcat taaaattatc ttctgcagca tctgcagcta tacaaagtgc
     1561 tataatagct aagcaagatt gttttgtacc accactaaat ggtatagttg gttcaagtgt
     1621 tgagcaaagt atacaaaact taggtagagt aagtgacaaa ggtatgtcta taacagatga
     1681 gataatctta aatgtaatga atgatatgaa taaagttgac tagtacttta taatatgttt
     1741 tgtattatga ggtataacaa aaatagcata aataaattta attagtaccc tctaataaaa
     1801 tatgattatg tataaattta tgtataatag aaaaaacttg ttaatgcaag ttttttcttt
     1861 ttttgtctaa aatatatagt atgtaattta gtgtggatat atgaactact taaaatataa
     1921 gatacattgt taataattgt tgaatgaaca taaaaactca ataatattga ctaatattga
     1981 ataagagtat tgaaaaagtg agcaatctct tataaaatta agaaggatta ttacaattgg
     2041 aggtcttttt atggatatag aaacaaaaaa atgggaagta ttgtattcag aagaaaaaat
     2101 taaagataaa ttaagggaat taggagcaat tatagaaaaa gattataaag ataaaaatct
     2161 tatggtagtt tctctattaa aaggtagctt tatattttgt gcagacttag ttagaaatat
     2221 aaacttacca cttagagtta attttatgac tacatctagt tatggaaaca atgaagaaag
     2281 tactggaaag gttaaagtag tttcagatgt gactactgat atagcaggat atgatgtttt
     2341 ggttgtagac gatattactg attctgcact tactatggat tttgtgttaa aacatctaaa
     2401 agctaaaaat cctgctagtt taaaatgctg tgttcttttg gataaaccaa gcagaagaaa
     2461 agtcgattta gtgccagatt attgtggatt tgaaatagaa gataagtttg tggttggata
     2521 tgggtttgat tttggtgatt attatagaaa tgttccttat atattcaatg ttactgatga
     2581 agatagataa gcaattatat aattttgtgg atgccttaat atgattttta ttaatcgtgt
     2641 tgaggttttt ttatttaaaa agtaattaaa gtagtattaa attaatttta tgcaatttaa
     2701 ttatctattt tttatagcat aataaaaaaa ttttaaataa ttgatgggaa atgagttttt
     2761 taattgtatt aataattgta aaagagtact aataattgta aaagatttta caaaaaagta
     2821 atgaaattta agaatcaaag catatatgtt gatataagca aatagataca ttatcacata
     2881 agaaattgtc gattcatata attatataga gtaatactca atatttatag agtattactc
     2941 taactttaaa aaaggaggat taattatatg agtgatattt caggtccaag tttatatcaa
     3001 gatgtaggtc caacagggcc aacaggtgct actggtccaa caggaccgac ggggcctaga
     3061 ggtgtaactg gagcgaccgg agcaaatgga ataacaggac caacaggaaa tacaggagca
     3121 actggagcga atggaataac gggtccaaca ggaaatatgg gagcgactgg accaaatgga
     3181 acaacaggtt ctacaggacc aacaggaaat acaggagcga ctggagcgaa tggaataaca
     3241 ggtccgacag ggaatacagg agcaaccgga gcaaatggaa taacaggacc aacaggaaac
     3301 aaaggagcaa ccggagcaaa tggaataaca ggttctacag gaccaacagg aaatacagga
     3361 gcgactggag caaatggaat aacaggtcca acagggaata caggagcaac aggagcaaca
     3421 ggaccaaccg gactaactgg agcaacagga gcaaccggag caaatggaat aacaggacca
     3481 acaggaaata caggagcaac cggagcaaat ggagtaacag gtgctacagg cccaacagga
     3541 aatacaggag caacaggtcc aacaggaagt ataggagcga ctggagcaac aggaacaact
     3601 ggggcaacag gcccaatagg agcaacagga gcaacaggag cagatggaga ggtaggtcca
     3661 acaggagcag taggagcaac aggtccagat ggtttggtag gtccaacagg cccaacaggc
     3721 ccaaccggag caaccggagc aaatggtttg gtaggcccaa caggcccaac cggagcaacc
     3781 ggagcaaatg gtttggtagg tccaacagga gcgacaggag caacaggagt agctggggca
     3841 ataggtccaa cgggagcagt aggagcaaca ggcccaacgg gagcagatgg agcagtaggt
     3901 ccaacaggag cgacaggagc aacaggggca aatggagcaa caggcccaac gggagcagta
     3961 ggagcaacgg gagcgaatgg agtagcaggt ccaataggtc caacaggtcc aacgggagaa
     4021 aatggagtag caggagcaac aggagcgaca ggagcaacag gggcaaatgg agcaacaggc
     4081 ccaacaggag cagtaggagc aacgggagca aatggagtag caggagcgat aggaccaaca
     4141 ggcccaaccg gagcaaatgg agcgacagga gcaacagggg cgacaggagc aacgggagca
     4201 aatggagcaa caggtccaac cggagcgaca ggagcaacag gagtgttagc agcaaacaat
     4261 gcacaattta cagtgtcctc ttcaagttta gtgaataata cattagtgac atttaattca
     4321 tcatttataa atggaactaa tataactttt ccaacaagta gtactataaa tcttgcagtt
     4381 ggagggatat acaatgtatc tttcggtata cgtgccacac tttcacttgc aggatttatg
     4441 tcaattacta ctaactttaa tggagtaact caaaataact ttattgcaaa agcagtaaat
     4501 acacttactt catcagatgt aagtgtaagt ttaagctttt tagttgatgc tagagcagca
     4561 gctgttactt taagttttac atttggttca ggcacgacag gtacttctgc agctggatat
     4621 gtatcagttt atagaataca atagtttata tgatgaaaag attataaaat aataaacaat
     4681 atgatttcat ataccaataa atagaataat atttaatagg tttatatgat gaaaagacta
     4741 taaaataata aacaatatga tttcatatac caataaatag gataatattt aataggttta
     4801 tatgatgaaa agactataaa ataataaaca atatgatttc atataccaat aaattaggat
     4861 aatatttaat aggtttatat gatgaaaaga ttataaaata ataaacaata tgattctata
     4921 taccaataaa taggataata tttaataggt ttatatgatg aaaagactat aaaataataa
     4981 acaatatgat tccatatacc aataaatagg ataatattta ataggtttat atgatgaaaa
     5041 gactataaaa taataaacaa tatgatttca tataccaata aataagataa tatttaagaa
     5101 aaatgattat atttaaaagg taagcataaa atttataaac ttttagaata gaaatctcaa
     5161 tcaattagat attcaaattg atgaatatga atacctaaat agattgagat ttattatgta
     5221 caaaacttat cctaatatat ctgacatttt ataaagccca gattgcttac caattaaaaa
     5281 tttagctgca actatagagc cgtttgcaaa tacttcatca gattgagaat gatggcttaa
     5341 tgtaagaact tcattatcac ctgcaaatac aacatcatgg tcgctgatta tattgccacc
     5401 tcttatagag tgtattccaa tttcatttgg ttttctttta caatctctac catatctacc
     5461 atgtgtattt tcactttcag gcaagacttc tctaattgca ttagctatca tagtagcagt
     5521 tccactaggg gcgtcttctt ttctattgtg atgtttttct atgatttcaa tatcaaaacc
     5581 ttctaacatc tttgaagcat ccttaactaa ttttattaat atatttactc caagagatgt
     5641 atttgatgat aataatatag gaatgttttt tgatgcttct tctattttat ttaagtcatt
     5701 ttcgtcatat ccagtagtag ctaatactac aggtgtatta ttttttagag catatgacaa
     5761 tattggctct aaagtatcat gatgtgaaaa gtctataatt acatcagttt tttcagttac
     5821 atcagtcatt gttttgtaaa gctttgtatc actatgatga cctttttcat cagcagacct
     5881 agctacacca caaaccaact ctaattcatt atcttttttt acacattctg ctaaaactct
     5941 tcccattgtt ccattatagc cactaattat aactttcaac ataaattcct cctatgaaat
     6001 taataaaaat ttgttatatt tctataagtt tattttatca ctaatataat ttatataaaa
     6061 taatattagt gataataagc ttacaattta tcttacatta aaaaatttaa gtggattttt
     6121 caaaatatag ataaatttct ttttcattgt ttaaatgata aaaatatatt tgacttcata
     6181 ccaaaaagag tgccccatga actaaaaagt taattttgaa ataccatatt catatatcat
     6241 atgatttatt tggaaattaa tattaataca ttaaaataac taaatacatg tatgcataaa
     6301 gatgtataaa aaatatataa acatatagta ttaattttaa attcaacaat ttaattgtta
     6361 aaagtgttat tattaaatta gaaatatctt aacttaatat actgagatgg gagtgataga
     6421 tatgttaaaa gaagaaaaaa cttatcaaga gaaagacgca aaagtattca atggagtggc
     6481 agctttgata atgattttat tatttttagt agtttcaata ggtatcatgg tttttgggat
     6541 agtaaaactt gatagtggat ttactggaat aggttcactt atgttaattt tgggacttgt
     6601 atttatagta gtagatttta tcctattttt tgggctaaaa atgattaatc ctaaagaagc
     6661 tatagttcta gttttgtttg gtaactatta tggaactata aaaaaagaag ggtactattg
     6721 ggtgaatcca ttttgttcag caataaaccc agcagtatca agaattaatg tatcgaaatc
     6781 ttcatctgat gaaaaggtag atatatcaac taattcaagg ggcaaaaaag tatctttaaa
     6841 aacaatgact cttaataatg aaaagcagaa agtcaatgat ttattgggaa atccaattat
     6901 aataggagtg gttgtaattt ggaaggttat agatgcaaca aaggcagtat ttaatgtgga
     6961 taattataat acattcttat ctattcagtg tgattctact attcgcaatg tttcaagact
     7021 ttatccatat gatgtatctg aagatggaga tgaaaaatct cttcgtggta gtagtcagga
     7081 aatagcagat agattaaaag atgaattaca atcaagggtt gacattgcag gaattgaagt
     7141 gtgtgaagtg agaattactc atctttctta tgcaccagag attgcagcag caatgttaca
     7201 acgtcaacaa gcagaggcta taatagcagc acgtaaaaag attgttgagg gggctgtaag
     7261 tatggtagag atggcattga ctaatttaag tgaaaataat gttgtgactt tggacgaaga
     7321 acgtaaagca gctatggtaa gtaatctgtt agttgtgctt tgtggcaata aagatgcaca
     7381 accagtggta aacagcagtt ctatttatta aattataaaa agtttaatag tttattttat
     7441 tgatatatag aaaatttagt agttcatttt attaaattat ataaagatta atggtttgct
     7501 ttattgaatt ataaaaagtt taataattta ttctattgat atatagaaaa tttagtagtt
     7561 cattttatta aattatataa agattaatgg ttttcacttt attaaattat aaaaagttta
     7621 atagtttatt acattgatat attgaaaaat tgaaggaaat aaaaatactt gtcagcaaga
     7681 aataaaaatg atataagaat gaataagaga attgtaaaaa aataaaatga ttataaataa
     7741 aagataaaaa tattgtaaaa aagagggtgc ctctggtgaa ttaaattcac acagagacac
     7801 ctttttaatt aattttttaa attagtatat tattgtttaa ttaatagcat agtactattt
     7861 aattaatcta aatttctaag gtcttccata agcttagttt tgtcagccgt tttttcatct
     7921 ttcattttta taactttagc aggagaacca gcaacaacgg caccagcttc tacatcagta
     7981 gttacaacag caccagctgc aacaacagca cctttaccga ttctaacacc ttcaagaata
     8041 actgcattag ctcctattaa aacatcatct tcaactataa caggagtagc agaaggtggc
     8101 tctaaaacac cagcaacaac agcaccagca cctaagtgaa catttttacc aagagttcct
     8161 ctagctccaa taacagcatt catatctacc atagaacctt caccaataac agctcctata
     8221 tttataacag ctcccatcat tacaacagca tttttttcta tagtaaccat gtctcttatt
     8281 attgcacctg gctcaattct tgcatgttca cttaaagtat tttttagagg aatagcagaa
     8341 tttcttctat catattctac atgagtatct gttatatcat ttccatgttt atctaatact
     8401 tccattatat cctcatagtc acctacaaat atataagaac cattacttcc aaatacctta
     8461 aatttatcag ttgattggaa gtgtaaagag ttagtattta catatacctt aacaggtgtt
     8521 ttctttttaa cttcttttat ataccttgct atttcataag catcgtttaa atttaccatt
     8581 tgttaattct ccttgtattt cattatattt cttttattat atacttattt gtcaatttta
     8641 gtatatactt acttcttatt atttatattt tattttagtt agcttttatt gtatagacat
     8701 agtattaaat aaatttatta tatatgtttg atttgtattg catattatta tatatatatt
     8761 gtatatgttt aatttatatt gtgtattatt atatttatac tattatccca acatgctgtc
     8821 catattataa aatcctggtt tttgcttaac taagtatttg gcagcagcta tagaaccact
     8881 tgcaaagata ccacgagatt gagcttgatg gcttattgta agaacctcat tgtctccagc
     8941 aaatagagca tcatgttcgc caacaatatt tccacctctt atagcatgaa taccaacttc
     9001 atttggttgt ctttttgcac tacgaccata tctaccataa ttattttcaa cgtttggcaa
     9061 aacctctttt atagcgttag caatcataac agctgtgcca cttggggcat ctacttttct
     9121 gttgtgatgt ttttctatta tttctatatc aaatccttct agtaatttag ctgcatcttt
     9181 aaccaatttt actaatacat ttacaccaag agacatatta tatgattgga atacaggaat
     9241 aactttagcc gcttcacgta ttttgttcat ttcgtcatca ttatatccag tagtagcaat
     9301 tactaaaggt gttttagtct ttaaaacgta agataagata ttatctaaat tagagtgatg
     9361 agaaaaatct ataactacat cagcttcctc aactatagta ctcatatctt cataaatttt
     9421 aaggtcgcct tcatagctat ccagacctct agctgcaaca caaaccaatt ctaattcatt
     9481 atcttctctt atagtatcgg ctaaaatctt acccattttt ccatcataac cagttgctat
     9541 aacttttaac ataatttcct cctatgatta agggctaact tttgaccaaa cttacttttt
     9601 accatgcatt aatctttact atgcattaac ttttagtcca aagttaacta attctttctt
     9661 taatacttct aaatttgctg ggtccatttc tgctagaggt aatcttaaat ctccaacatt
     9721 gaatcccaat aaattcattg cagtcttaac tggtatagga tttacttcta taaataaagc
     9781 tgcgattaga gcatccatac caagttgtaa ttttctagaa ccttcaatat cgccttcaaa
     9841 gaatttagct accaaatcgt gagtttcttg agggcaaaca ttagcaagta ctgatataac
     9901 tccttgacct cctaaagata ataaaggaag tatagtatca tcattaccag agtagatagc
     9961 aaagtcatct ggaactaaac tagctatttc tgcaacctgt cctaggtctc cactagcttc
    10021 ttttacagca actatgttat caattttagc aagttcaact ataaggctag gacttatatt
    10081 tacacaagtt cttccaggga cattgtaaag tataattgga agtttaacac tgttagctat
    10141 tgtttcaaaa tgacgcttaa gtccagcttt attagcttta ttgtaataag gtgttattat
    10201 taatagagca tctactccta atttttcagc ttcttgactt aagttaactg agtgcatagt
    10261 atcattagaa ccacttccag ctataacagg aactctttta ttaacttttt caacaacata
    10321 cttaatagta gcaagttgtt cttcatcagt catagtatta gcttcaccag tagtaccaca
    10381 agatactata gcatcagtac cattagctat ttggtattca actaattcac ctaatttgtc
    10441 aaaatcaact ttgttatcct ttgtaaatgg tgtaactaga gcaacagcag aacctttaaa
    10501 tatcatataa aatcaatccc ctctttttta tttttgtgtt ttatattaca gttacttcta
    10561 atgcttgttt ttgagttact attaatattt tacaaaatta tatatttata caagtttgta
    10621 tattatacta aatcgtatga taaagccatt tcagctattt gaattgcgtt agttgcagca
    10681 ccttttctta tattatcagc aacaacccaa agatttacac cattatcaac actaaaatct
    10741 cttcttattc ttccaacaaa tacttcatct ctatcatcaa attctacagc agttggatat
    10801 tcgtttttag caggattatc aactactaca acacctggag cttcttcaag tgtttttact
    10861 aaatcatcta actcaaatgg attgttaaac tcaacattta tagattcact atgaccattt
    10921 tttactggaa ctcttacagt agttgcagtt atttttaaat cgtagttatc aagtattttc
    10981 atagtttcat ttaccatttt catttcttct ttagtgtatc cattttcagt gaatgaatct
    11041 atatgaggaa gacagttgta agagatttga tgagggtaga atccagtagg attaccgttc
    11101 attcctttct ctaaatcttc aacaccttta acaccagaac cagatacagc ttggtaagta
    11161 gagtaaacaa ctctcttaat tttgtattta tcatcaagag ctttaagggg aaccatagct
    11221 tgtatagtag agcagttagg attagctatt atacccttat gattttttat ggcttctgga
    11281 ttaacctcag gaactactaa aggcacatct ggattcattc tccattgact agagttatct
    11341 actactaaga ttccatttga agcagctatt ggagcatact tttcactaat acttccacca
    11401 gcagagaata atgctatttg tatgcctcta tcagtaaatg aagtttcctt taattcttct
    11461 actatatatt ctttaccaca aaacattact ttagaaccag ctgatttaga agaagagaat
    11521 aaaaatagat tttctattgg aaaatttctt tcttctaata cttttaaaaa tgttctacct
    11581 accattccag tagcaccaat tattgctaca tttacttttt tcatataaat tcaccccaat
    11641 tttaaattat taaaacatta ttttatttta gttatacaag taagatatgt taatattttt
    11701 atatatccaa aaactttaat attatattaa caactttaat tatatacaaa aaacgtacaa
    11761 aggtatactt tgtacgtcta atttatcact caaagtaaac cctgtagctc atcacctaca
    11821 aaaataagtg acagtattac acatgttatg tgcaatccca gaaaatatta ttgcaagaaa
    11881 tattttcttc ggctgtaaat cctttttcca atcattaaca cctgccagct actattggat
    11941 actcttagtt acagctacct ctaccctagg ttaataggat attaaaattt gattattcta
    12001 ataataatac atatttaaga aaaaatcaac ttatttatat aaatattgct aaaatttaaa
    12061 tccaaaattt gtcaattctt gttttaacac attaagatta gtttcttcca tttcagctag
    12121 aggaagtctt aaatcaccaa cattaaaacc taaaatgttc atggcagttt taacaggaac
    12181 tggatttact tctataaata aagcagcaat taaagcatcc atatcaagtt gtaatttttt
    12241 tgagccttca atatcacctt caaagaattt agttactaaa tcatgtgttt ctttaggaca
    12301 tatgttagca agtacagaga taataccact tccacctaat gataatagtg gtagtatagt
    12361 atcatcatta ccggagtata tagcaaagtc tttaggtact aatttagcta tttctgcaac
    12421 ttgagctaag tctccacttg cttccttcac agcaactata ttatctattt tagcaagttc
    12481 agccacaaca gatggcttta tattcacttt agttcttcct ggtacgttgt ataaaataat
    12541 tggcaactta acgctatttg ctattgtttc aaagtgaagt ttaagacctt tctcattagt
    12601 cttattatag taaggagtta ttattaaaag accatccacc cctaattttt cagcttcttg
    12661 actcatatga acagacaaca tagtattgtt tgaaccagta cctgctataa caggtattct
    12721 cttattaact ttttcaactg tatattttat tacagcaaaa atttcagatt cactcatagt
    12781 agtcgcctca cctgttgttc cacaaacaac tagtgcatct gtgccattct caatgtgata
    12841 ttcgattaat tcacctaatt tttcaaagtt gacattatta tcctctgtaa atggggtaac
    12901 taaagcaaca gcagaacctt taaataacat ataatcaaat ctcctttttt atctaaattt
    12961 aattttttaa gtacaataat aattatagta caaattaatt aattttaata ggtatagtta
    13021 atatcttaac tgtttaaata agatatttat attatattaa tattagaaaa attttaaata
    13081 aatgttttat tctcaaaata tgcatattaa tttaataaaa tataccaaaa tggaaataaa
    13141 aaataaattt tatgagaatt taataactaa taattaatat atttaggtta taataaatat
    13201 gtgcgtaaaa tctaacaata agcaataata ccgtaaattt aggaggaata atatggatac
    13261 tttaaaggaa ctttttaaaa taggaagtgg accttcaagt tctcatacta tgggaccaca
    13321 aagagcagca gagagattta agaatgaaaa cccagatgca gaaagtttta gagcaatatt
    13381 atatggtagt ttggcagcta cagggaaagg tcacttaact gactatataa ttgaaaaaac
    13441 tatagcacct aaaaaagtcg aaattgtttg ggaagaagat attataaaag attttcaccc
    13501 aaatgggatg aagtttgaag ctttagataa agataaaaat gtaacagctg aatggactgt
    13561 atattctgta ggtggaggaa ctatagcaga agaaggtcaa agaaacagta aaagcaatag
    13621 tatatatcac ttagatacta tggatgagat agtaaaatgg tgcaaagaaa ataataagac
    13681 tttggtagat tttgtgttgg aatgtgaacc aaaagacata aaagattata taaaaactat
    13741 aaaagatgct atgagaaaat ctattgatga tggactaagt acagatgaaa taataccagg
    13801 caagttatta ttaaaaagaa gagcaagtac attttataat gcatataaaa aagataagag
    13861 cttctcaaca cttgtatatg catatgcact agcagcttca gagcaaaacg cttctggtaa
    13921 tataatagtt acagcaccaa cttgtggttc tgctggagta ataccaggaa tattctttgc
    13981 aatgcaggat ttctataatt atgatgacga aaaaataatt gaagcactac ttgtagctgg
    14041 aataataggt aatataataa aaactaacgc ttcaatatct ggagcagagg tagggtgtca
    14101 aggtgaagtt ggagccgctt gttctatggc agcagcagca gtagcatact taaaaggtgg
    14161 aactatagac catattgaat atgcggcaga aatagcactt gaacatcatt taggaatgac
    14221 ttgtgaccct gtatatggat atgttcaaat tccatgtata gaaagaaatg caatggcagc
    14281 tcaaagagct tatgatgcag ctaattatgc attattaact gatggctcac attctgtctc
    14341 cttagaccaa gttgttgaaa caatgaaaga aactggtata gatatgatgg ataagtacaa
    14401 agaaacagct aagggtggac ttgctaaaca tttcttctct tgctaaaaat aaaattttcc
    14461 aataataatt cctctgtttt gatttatgaa acaggggaat tattattaat ggtgaattat
    14521 ttaataatgc aaaatatttt tatattcaat ttagcttttt atttttaatt agtataacat
    14581 gctatataat attttaatta taaagaaata tagaaatatt ttttaataaa ttagaaattg
    14641 gaggagatta catgagagag gcatcatatt tacaagaaca actttataaa cataggaagt
    14701 cattaaatcc tattgcagag attgggagaa aagagtataa gacttcaaaa tatataagag
    14761 attatcttga taaattagga attgagtatg aagtttattt agaaacaggt atagtaggtg
    14821 taatagaagg taaaagacct aaaaaagata ttgcttttag agctgacata gatggtcttc
    14881 atagtgaaga aggggtaaaa catttatgtg gtcatgatgg acatgctact atcttacttg
    14941 gattaattga gtatttaaat gataataaag aagacttaaa tgataatata gtatttatat
    15001 tccaaccggc agaagaaggt cctgggggag caaaagcttt aatagatgaa ggagtgctta
    15061 gaaaatacaa tattgatgaa atatatgggc ttcatatata tccagagtta ccagaaggtt
    15121 atgtaggtac aagagagggc tattttatgg ctcaaatagg agatattgac atagaaatag
    15181 tgtctaaaag tggacatggg gctatgccac aaaatggtat tgatggtata gtgatagctt
    15241 caaactttgt aagctcactt caaactatag tgtctagaaa tataagccca atagacaatg
    15301 cagtgttgac tattggcaga attgaagggg gagctagaag aaatataata gctgaaaata
    15361 taaagatgga aggtactatg agatgtttca gcccagaagt gtatgagaaa atgaagctta
    15421 gagttagaga acttgctaga gggtttgaat tggcttataa ctgtaaggtt aatataaata
    15481 ttatagatga ttatatcgct gttaaaaatg acaaggattt gtatcaagag tttgtagagg
    15541 ctattggaag tgatactgtt gtagagttag agccacttat gatatcagaa gatttttctt
    15601 attatcaaaa agaagttcca ggattatttt ttatgttggg ttcaagaaac gaagaaaaag
    15661 gatttgtaaa tggtcttcat aatataaact ttaattttga tgaaaagata tgtgtaaatg
    15721 cattgaatgt ttattcaaaa ttattaaaat acaaagaagc aatagattag gaagataagt
    15781 tataaagatt aaaaagcata aatacctaaa tttaaaaaaa gtgtattaat aaatacccct
    15841 tacatatttg tataaattta ttttaattga caaaaataca aataagaagg ggtgattttt
    15901 ttgaaagaaa aagtacaaag agaaaagaag ataactaatg gcaagaatac taaaatattg
    15961 acaaatgatg atataatgaa atatgagata gcctcagaac taggtcttat ggataaagtt
    16021 ggtgaacgtg gatgggcagg acttacagct aaggaagcag gaagaattgg aggtatgctt
    16081 acatcacgca aaaagaggct taaaaagatt gtggaggagc agaataaaaa ggatgagtca
    16141 atatagtgat tttgcgtttg tatatgatga acttatgaat gaagttgatt ataatggttg
    16201 ggttaaatat atagaagata taatagatag tgaaggtgta aaagtaaaaa atatattgga
    16261 attggcatgt ggcacgggta atcttacaat tccattgact aaaaaaaatt acgatatagc
    16321 tggtatagat atatctgatg agatgcttag tgtagcaaga gaaaagtcag aaaaagaagg
    16381 agtagaatta gttttacttc aacaagatat atcagagctt gattttgaaa tatctgattt
    16441 ggactgtgta ctttgtgctt gtgatggatt caattatata acttatgatg atgatttgga
    16501 aaatgtattt tcaaagacat atgaattatt aaagaaagat ggaatattca tatttgatat
    16561 aagttctttt tataaattag ccaacatatt gggaaataac atgtatggag aaaatagaga
    16621 agatatagcg tatatgtggc aaaattactt tgatgaagaa gagaatctaa ttgaaatgga
    16681 acttacattc tttattaaag atgaatgtgg aaaatttgaa agatttgaag agatacacca
    16741 acaaagagca tatactgaag atgagatagt tgatatgctt gaaaaatctg gatttaagga
    16801 tataaaatat tatggggatt ttacatttga caaacctagt gaagaaagtc aaagaatctt
    16861 ctttgtatgt aaaaaataag atatttttga ctatataaga taattattaa aaataaccat
    16921 gatataaaaa tatagaaaat gcagttttat agattaaaag taaagtgatg atactttatg
    16981 acttttattt tttaataatt ataaagttct atagataaaa attaaaatat aataactatt
    17041 gcttagtaaa attaaaataa aatgggtttt gcccaaggtt aagatagata agtatttata
    17101 gattaaaatt aaggtagtaa tataataaaa ataagacaat taacgggaca tggaggaata
    17161 ttaatgagag attatgtact aagagcgaca tcaggaaatg gtcaagttag agcatttgtc
    17221 gcaactacta gaaatacagt agaagaagct agaagattac atgaaactac aaaagtagca
    17281 acagcagcac ttggaagaac attaacagcc acatctataa tgggattaat gatgaaaaat
    17341 gatagtgata aattgactgt aataataaaa ggtggaggtc caattggaac tattatcgcc
    17401 acatcagact ctaagggaat ggtaaaagga tatgtaggaa atccacaagt agaggttgaa
    17461 gactatccaa atggaaagtt aaatgtagca gcagcagtag gtacagaagg tgttgtaaaa
    17521 gttataaaag acttaggtct tagagaacca tataatggga cttatccatt ggtaagtgga
    17581 gaaattgcag aagactttac ttattatttt gctgtatcag agcagactcc atcagtagta
    17641 gctttaggtg ttcttacaaa agaagatgaa gtagagtttg ctggaggatt tatagttcaa
    17701 ttaatgccag atgcagaaga agagactatt gctaagttag aggaaaatgt agctaaatta
    17761 ccttctataa ctaacatgtt aaaagaagga aaatcaccag aggatatatt aaatattgtt
    17821 ttggatggtt tggaacctaa aatacttgat acctgtgaag ttgggtttat gtgtgaatgt
    17881 tcaaaagaaa gagtaaaaac tgctttggtt gcaattggta aaaaatcatt ggctcaaata
    17941 atagaagaag ataaaaaagc agaagttggt tgccagttct gtaataagaa atatatgtat
    18001 agtgaagaag agttgcttga aattttaaag gaaatgtaga ctataaaaat agttgtattg
    18061 atataagtaa tgttatagtg atatagtaaa gtcgtattga tatagtaatt aaagtataat
    18121 ttattaataa tagacatatt tatattaaaa aataagttta ataaattttt aagcttaata
    18181 aattttaaga attaagaagc tttctggctg taatgtttgc aatgttgcag ttagaaggct
    18241 tttttatttt attatagttc gtgtcaaaga ttgtatgaaa caataaaata ttgtaaaata
    18301 atttgtatat ttagacctga ttggcacaaa ggtttataag gtatttgagt tgattatgcg
    18361 aaattctatg aagtagtaac cctgtgactt taatcatggg aggttcagaa gaaggagaaa
    18421 attttaaata tggaaagtaa aacgaagtac ataggaataa gtatattaat attattgatg
    18481 atatttttaa ttgcaaaaaa ttttaacgga aaacttgaaa tacctattcc tgagagtaat
    18541 agtagaaaat ttaaatcagc agcagtgttt tatcctcaac atcaagatga tgaggtttta
    18601 tggggaggaa gtgccattgt agatgctata aaacagtgtg gtgttgataa tgtatatgtg
    18661 gtattagtat cagatggttc tggagttaac gttttcaaag ctaacacaaa atttagaaat
    18721 ttaactagga agcaaaagga agaacttaga aataacgagt ttaaatcagc tttgagagag
    18781 cttggagtga aacctcaaaa tgtgattata cttgcagata tagataaaaa ggaaggcaca
    18841 cattatgaat taatggaaaa gactatattg gattttgaac ataagtttaa aggcaatgtg
    18901 acccatatag cccatcacta taagtatgat gaccatataa tgcatagaaa gaatggggaa
    18961 gttttaaaga aacttaaacg tgaaggtaag ataaaagatg acttgtattt tgttaagcca
    19021 aaatatgtaa agtatatacc aagaaatgaa agagctatct ataaagcaat ggattttgat
    19081 gactacaata aggttaagag tgcttgttat gaatataagg ttgtaaattc aaagcgtaaa
    19141 atgtatggta taggatatat ttcggcacat agttattttg aacatcttct aaatgaccct
    19201 gaacttacgt ctgtattaag tgaagattaa tttcttataa gtagtaagtt atgtttgata
    19261 agttgattgg aattttctat agttttgaag gtattggaaa tttagtttta tttaaagatt
    19321 taaagataga ggtttttagt gtttaaaatt ttaaagttaa gttgaataat tgtatagaat
    19381 tatttgtgaa agaagaaaca gtgtaaaaca tagtatctta tttatggttt taaaatcata
    19441 ggcaagatac tttttttatg taactaatac cattttgaga ttattaactt aagaatttta
    19501 tataatttaa cactcatata taatgatgat atttaggtag aatagatgca attacgctta
    19561 aataaaataa ctgtattttt tataaaaatc aaaccctaca ctatactacc agataaaatc
    19621 tacatgctat aatttgacct gtgtttataa aaaaaggagt aatctaataa aatagtattt
    19681 cacttatgta taactaacaa ctattattac gattttctct aaataattta aagaaaaata
    19741 atgcaggagg taaaatatga acaatgaatt tataatttta aaaggttgca aagagaacaa
    19801 tttgaacaat atttccttaa aaataccaaa aagaaaaata accatattca caggggtgtc
    19861 gggttctgga aagtcatcta ttgtatttga gacaattgca aaagaatcac aacgccaact
    19921 aaatgaaagg tttagtacat ttgtaagaag ttttttacct aagtatggag aggttaaagc
    19981 tgattgtata gaaaatttgt caacaccaat tatcatagac caaagtagac ttggtggaaa
    20041 ttcaaggtca accctaggta ctattacaga tgtaaattcc tttttaagag ctttatattc
    20101 aaggtttggt agtgagtata taggtaatgc taatatgttt tcttttaata atattgatgg
    20161 tatgtgccca cactgtcatg ggcttggaaa aaagctagtt cctaatatga accaaattct
    20221 tgatatgaat aaatcattaa atgaaggtgc tatattgctt tcagggtttg gagtgggttc
    20281 ttggcattgg aatatattcg ctgaatcagg attttttgat attaataaga ggatatgtga
    20341 ttattcagaa gtagaattgg aaaagttttt gcatggtaaa gcagaaaaga ttaagataga
    20401 aaatgctggt caaactaaca tgacatatga gggattaatg gttaaattta atcgcctata
    20461 cttaagtaga gagggagaaa tatctgaagc tactaagaaa aaattgagta aacttcttat
    20521 agaagataga tgtcctatat gtgatggaag aagacttaat gaaagagtat ataggtcttt
    20581 aattaatggt tataatatag cagatttaac tagtatgcaa attgatgaat tggctgaagt
    20641 tattaaaagt atagatgagc cagaagcaca acctttaatt aaaggaataa tagaaaagtt
    20701 aaacagtatc atagatatag gtcttggata tttaacactg gatagagaga catcttctct
    20761 atcaggaggg gaatctcagc gtataaagat ggttaagtat ttaaatagta atcttgttga
    20821 tttaatgtat atttttgatg aaccaagtgt aggacttcat ccaaaagatg tgtataaatt
    20881 aaataatctt ttaaaaaaat tgcgtgataa agggaataca attatagttg ttgaacatga
    20941 cccagatgtt attaagattg cagaccatat tgtagatgta ggaccaaagg caggtaagta
    21001 tggtggagaa gttgtgtatg aaggcagtta tgaaaatcta cttacaagtg gtactttgac
    21061 agggaatgct ttaagtaaat ttcttcctat taaagaaagt gtaagagaac atagtggata
    21121 tttagaagtt aaaaattgta ataaaaacaa tttaaaaaat gtatcgatta agatacctaa
    21181 aggtgtattg actctagtta ctggagtagc aggagcaggt aaaagtacgt tgattaagga
    21241 tgaattttta aagcaaaatc ctagtgctgt acttatagac caaagccctg tttcagcaaa
    21301 ttcaaggtcg agtttggcaa catatagtgg aattatgaac aacataagaa gcatattttc
    21361 aaaaacaaat ggcgtaaatg cttctttatt cagttcaaat tcagaaggag cttgtgataa
    21421 ctgtaagggt tctggaatag tagaaatgaa tcttgctttt atggagagta taaagagtac
    21481 ctgcaatgtt tgtgaaggta aaaaatttaa aaaagaagtt ttagaatata ggtttcaagg
    21541 gaagaatata attgaagttc ttgaaatgtc tgttttagag gcaattgagt tttttaattt
    21601 aaaacagatt aaaacgaaat tacaatgtat tgaaaaaatg ggtattggat accttacttt
    21661 aggacaaact cttgatactt tgtctggagg agagtgtcaa agattaaagc ttgctagtga
    21721 attaaataag gaaagttcag tgtatatatt agatgaacca acaacaggtc ttcatatggc
    21781 tgatattgag aattttataa gtataattga agagattgta gataatggaa atacggtcat
    21841 aataattgaa cacaatatag atgtaattaa aagagctgat tggattattg agctgggacc
    21901 tgaaggagga acaaaaggcg ggagagtaat atttgaaggt attccaaaac aattatgtaa
    21961 caataaaata tcattaacag caaaatatat agtataataa ataaaatata ataaaattat
    22021 aatgatattt taataaatat aatgggtata taaaatgata attaaactta acagtaataa
    22081 ataatgtgag aaatattcaa atttaattaa ataaagtgtc agaaatttgt ttaaatttta
    22141 gtattttaac ggttctgacc ttttttctta tttttatgga gaatatcgag gatggagtct
    22201 ctaatagtta cttttttgtg tctacttgca agtttgatta aaaaatggct atacacactt
    22261 gtgacttcag tcatgggagg ttcagattat aatcttaata tataatttgt gaaataattt
    22321 gatgacgatt tgctgatgta taaacaataa agattaacta cattaaaatt taaatcttgt
    22381 taagtaaaac ttataaaagg agagagatgg atgataaatg atattctaac cttattatct
    22441 gaaagaagtg atttttttat aaagctatcc atagaacatt tgatgatttc tattatttct
    22501 ataataattg cgattgtttt gggtggtata attggtatta ttgtaagtga atttcataat
    22561 tcttctaaac ctatattggg aactatcaat tttctataca ccattccatc tatttctatg
    22621 ctaggatttc tgataccatt ttccggaatt ggaaatacta ctgctgttat tgcacttacc
    22681 atttatgcat tattgccaat ggttagaaat acatatactg gaattactaa tgtggataaa
    22741 aatattcttg aagcagctag gggaatggga agtacagatt ttcagatatt gtataaaata
    22801 aaacttccgt tagccctacc tgttattatg tctggtatta gaaatatggt gattatgaca
    22861 attgcattag ctggtatcgc ttcatttata ggtgctggag gtctaggtgt agccatatat
    22921 agaggaatca cgacaaataa cacaataatg acaattactg gaagtatact tattgctcta
    22981 ttagctttaa tatttgattt tattttaggg ctggtagaaa aattttttca acgaaaaaga
    23041 aaaaagaaaa ataggaaaaa agtttttgcc attctaggaa gccttattct tatagcaact
    23101 atctttacgt cttatttatt taatccttca aagactcaaa ctattcatat tgctactaaa
    23161 cctatgactg aacaatatat tcttggtgag atgttggata ttttaattga aaaaaacaca
    23221 ggtctaaacg tggaaattac acaaggtgta ggagggggaa catctaatat ccagccagct
    23281 atggagaatg gagaatttga catttatcca gagtatacag gtacaggctg gaatatggta
    23341 cttaagaaaa atgaattata tactgaaagt atgtttagta aactacagtc ggaatacaaa
    23401 actaaactta aaatgcaatg gactggtatg tatggttttt ctaatagcta tgcattagca
    23461 gttagaaaag aagttgcaga taaatacaat ttaaaaaata taacggactt aaaagatgta
    23521 tcttctaaat tgacatttgg agctgaatat gacttttatg agagagagga tggatatact
    23581 ccattgtgta atacatatgg actgaacttt aaagatacag ttgatttaga tattggatta
    23641 aaataccaag ctatcaatga aggtaagatt gacgtaatgc ctatatttac aactgatggt
    23701 cagtatagtg tttcagatgt tgtagttcta aaagatgata aaaatttcta cccatcttat
    23761 caatgtggaa atgttgttcg tttggaagta ttagaggaaa atccagaact atcaaaggta
    23821 tttaagatgg ttggagatat tttgactgat aaagaaatgg ctaaaatgaa ttatgacgta
    23881 gaaaacaaca atttagaacc tagagaagtt gctcgtgagt ttctgaataa gaaaggtctt
    23941 ttataaattg gaggaaatat aatgacacct attatacaat ttaaaaatat taaaaaacaa
    24001 tataatgata aaactataat agataatctt aatttagata tagaaaaagg agagtttttg
    24061 actgtaattg gttcgtctgg ttctggtaag acaacactct taaaaatgat taatggtctg
    24121 attttgccag atggaggaaa tattttgata aaccaaacag atatcaaaaa cgaggactta
    24181 attaaattaa gaagaagaat aggatattgt gtacagggaa gtgttctttt tcctcatatg
    24241 actgttgaag aaaatatttc atatgtacca aatctcctaa gtaaaaagaa taaattagaa
    24301 gtaaaaagtg ctgtaaacaa gtggatggaa atagtgggat tgccaaatga tatgaaagtg
    24361 cgttacccat cagaattgtc aggtggtcag caacaacgtg tagggattgc aagagcttta
    24421 gcttcttctc cagaaatttt attaatggat gaaccttttg gtgcagttga tgagattaca
    24481 cgaaagcaat tacaaaaaga gataaaagaa attcataaaa aaacaggagt tacaattatc
    24541 tttattacgc atgatattta tgaagctttg attttgggaa caaagacttt ggtattaaat
    24601 catggagttg ttcaacagta tgatactcct gagaatattt taaatactcc tgctaaccaa
    24661 tttgtagacc agttattgaa tataagaaaa tctataatag atgatgataa tttaaaagaa
    24721 taaatttaaa tttaaaatca aattgttgtg ataaaaacta ttgatttaga gctaacttca
    24781 agttgtatac ttgaagtgga aaagttagat taaggtatag aagggcattt agcagttggc
    24841 tgtagacgag gtaactgctg aaggtgcttt caataaatgg ctagaacctg tatctgttga
    24901 agattataat aaattgaaat aagaagctca atatacagag tagataggca cttcaaatag
    24961 aagtgtcttt tgtgtgccat aaaataaatc aaaatattag caaagaatgt gaaaaacaaa
    25021 ataaaataat atgctatctt taaaatagga gggatgctat atggataaca atttgattac
    25081 cattgaaaaa actttagatt atatagaaaa acatctttta gatgagatgt tagatttaaa
    25141 tgtaatttct aaagagatag gctattcaaa ataccattta catagaatgt ttacatcagt
    25201 tgtcggattt agtgtacata attatataca aagacgtaga cttactgaag cagcgagaat
    25261 gctaattttt acagaaaaac caattattga gattgcttta atctcggggt atgatacaca
    25321 acgctctttt tcaagagggt ttaaaaaaat gtttaaacgt agtcctaatt tttttagaag
    25381 acatcaagat tttttaccac tacaattaaa atttgatatt cataatagaa aaaaattacg
    25441 tggagatatg gttttagatg ttaaaaaagt taattgtgca gatataaata ttgttggcta
    25501 ttctggtaaa gtaagaaaag gatttcatat tattggaaaa tgctggaggg atttgcataa
    25561 aaataaagag atgatagaaa ataaggtaga tttaggtttt ttaattggag ttagtgatta
    25621 tagcaatttt aaagagattg agaatactcc tacatttaca tacattgcag gtgctcaagt
    25681 agctactttt ggcaaattac ctaatggaat ggaaaaattc gtattaccga aaagtaatta
    25741 tattgttttt acttttattg ggaaaaatga ggatagtatg caaaatgttg tagaatatat
    25801 ctatcaagaa tggttcccta attcaagttg ccagtttaat gaaaataatt tatatgactt
    25861 tgtaaaatat ggagaaaaaa ctgatgagaa tggtttgagt gaaattcagt tttgggttcc
    25921 aatcatttaa aagaaggtat tatgtataaa gtagatggat ttatataggc aaagttttac
    25981 agcagtatgt atttataaat aatttatagt ttgtaggaaa gaaataattt tactataaga
    26041 ttatgataaa atacacaata ctatgacaaa atagtgttaa ataatagatt taattttgca
    26101 taggaaaagt tctataatgg tgtgtattca taaataattt ataatctgta ggaaagaaat
    26161 agttttacta taagattatg ataaaataca caatactatg ataaaatagt actaaataat
    26221 agatttaatt ttgcaaagga taaggtgttt taataaaaat gaatgtagaa aacgaattac
    26281 ttaaaaacct agatagattg catacaacag agttaggcgt tgtaagaatt aagaaaaatc
    26341 tttctttgga gacaaatgat gtagtgaact ggtgtaaaac taaaatagaa tctccaaatg
    26401 ccattattaa tagaaaggga aaaaactggt atataagtgt atatgattgt attataacag
    26461 taaacgctca cagttataca attattacag ctcataaaga aaagaaatga attgcaaaat
    26521 acaaaggtca aaagcatttt ccactgtttg tagtacctat gaagaagtat ataaaataat
    26581 attacttttg aataataatt taaattttgg aggttgaaaa aatgaatgat actgtaaaag
    26641 aaaaattggc agagtcacta acttctgata ctactgatat tttaccttat ttgccttatt
    26701 tattacaaga tttttgggaa ttaggaagtt caccagaaca aatgttacaa ttatttagaa
    26761 agcatatacc ttttaatgag gatacaaaag ttttggattt agcttgtgga aaaggtgctg
    26821 tatctgtgaa gcttgcaaaa gagttgaata tacatatcaa aggtattgat ttgatacctg
    26881 aatttattga ttatgctaga agaaaggcta ttgaatataa ggttgatgct ttgtgtgatt
    26941 ttgaaatgaa tgatgctaat agttctgtaa aaattgagca tgattatgat tgtgtgattt
    27001 ttggagctgt aggggatatt ttaggtaatt ataaagaaac tataagtaag ctattaccta
    27061 caataaaaag taaggggttc attttaattg atgatgcata tgtagtagat aaatctacaa
    27121 atgaacagct taattttgag agggtgtatc ccacttacaa tgagtggtgt atattgttca
    27181 aagaattagg tctgaagcta attgaatgta taccatgttt agaacttgaa aatgatgttg
    27241 aagaggaaat gaattggatt ataactcgtg caaatgagct aattaaaaaa tatccttctc
    27301 aaaaagatat gtttgaacaa tatgttatta gccaaaaaaa tgaatatact gatttacagc
    27361 aggaccttgt tggagcaact tggattttac aaaaagaata agataaatat tagactagat
    27421 aatcaatgtt atagtgaatt atcccatgtc tagtgaatat aaataacata aaaaaccgtc
    27481 aagatgaata gtttattcgt gcttgacggt ttttagtatt tgttgaagta aaattttatt
    27541 tctttagtat atcactttta gtcaatccat ttgatttagc ttgagtattc cattgatgat
    27601 tccccataag tttatatagg aatctaggga agttaggtga aataaaaata gtacttttgt
    27661 tggaatcatc tatatgtata ttatcactaa gtatattttt tgaaagttct tttaatgcaa
    27721 ttcctaaatc ttttttaggt cctttaccca aaggtacgga ttctagtgaa ccaaacatct
    27781 ccccagctcc aattccaata ccttgaaccc atgtaaagtt gattttttta caccaatgct
    27841 ctatcatttg aattgccaaa tgattatgtt caccttcatt gaatccacag ttaactattg
    27901 catacactgg aataggtttt ttattttgtg tttttaaaaa tttttcacat ttctctaaaa
    27961 aatgaagtaa atgagatgga ataccatcta cataaagagg agatgcgatt attaatctat
    28021 cacaattaag tatggcatta agagcgtcag gatacttaga tgtgttatct actttaaatg
    28081 taaaaacttt attatcattt tgaataagtt gttttaattc agataaaaaa tactgtgaat
    28141 tatttttatt tacttttgga ctaccattta tcattactat attcatatgg attcacctct
    28201 tatatcttgt atattttcat agaaacaaac agagtgttct tttatattga aatttatagc
    28261 atttccattt actaatttcg tagcagtttc tttttcagct tctgtaatac aatctccata
    28321 gaatatagct tttaaattta tctgtttatc atatctgctt ttatgacgca tcatattatc
    28381 ttttattaca aagtatggaa gaatataatt aatgctttta tcaagtacgt ttttgacaaa
    28441 agggctaaac cctccgtaac agcatctgct tattataata attccatcag agtcatttat
    28501 aagtttaccc atgttgctgt aataatcttt tacaacacat tcagaaggag ttttaatcca
    28561 gcaaccaaaa caaccaatac atttgtggat ttcttttgtg tttggaagta tttttatatt
    28621 gtcatcaagt ttgggtaata acttttctaa ttctttgtca gttaaatcat gtattaaaag
    28681 cctcataaag tccatctcct tttattatgt atgtttactt ctaaaaatta tatcttatag
    28741 atttttcagt aaatctttac accaattaat aacaaaatta taatagtcaa ctccataaat
    28801 cattgttgca tacatatatg tatattggtc aacacaatga ttttcttctg catcattttt
    28861 ttgtttactt aatttattta gaagtaattc tacttcagtt attaacattt ttaagtttgt
    28921 ttcaattatt tctttgggta gatacttgta aaagaatata ttaacaaggt ggtcttgctt
    28981 tgttttagaa aaatttatag gtttctttaa ccattcaaga aatacttctt taccagtatt
    29041 agttatggaa tatagttttt ttaatttgtt accatctata acttcgtgat agtgtatata
    29101 tccttttgtt tctaatcttt taagtgcagg atagatactt ccaaagctgg cgtcaaaaaa
    29161 gtacgaggta ctttctgaca ttatttgttt taagtcgtat ccacttaatt ctttttccat
    29221 taaaaatcct aaaataatgt attctaacat attacctcct ggtatcaatt agatatatat
    29281 cgattcgata tatttattat tacagataat aaatcttacg tcaagatgct ttttaagata
    29341 agctaaaaag aattaggagt tattgataaa tatgcaaaaa aattaatata aaaggtaatt
    29401 aaatatcaat aaagatttaa aaatagttaa atcaaagtaa gagtctaata tataaaattt
    29461 atagtaactt tatggtttaa atataaactt gtgtgctatt gacaaagtat aaaattagca
    29521 gtagaataat tgcatgagca aatagattgt tgcgaacgca aaaaaaggac aatagatatt
    29581 aaaggagaga atatgagaga gctattaaaa tgggtttcca ttataaatag atacaataca
    29641 aattatattg acaggaaatt ggcggatatt ggaatcaata atagccaata tttttatgta
    29701 ttacacatat gtaataatcc aggtattaca caggacacta tatttgagaa aattcttgtg
    29761 aatcctagta atataacaag agctttggca aatttagaaa aagaaggctt tataacaaga
    29821 gaaccaggtg taaaggataa aagaacatgg catttatatc ctacagaaaa atctttagga
    29881 tgttatgatg aaatactaaa aataacaaat gggtatgttg aggagttgtt gagttcattt
    29941 gagaaagaag agcaagagtt gtttatgtca atgttaaaga aagttgcatt tttggctatt
    30001 gatatgaatg aagaagcaaa attggaggcg aaggaaaatg gaagaaaaat ataaggagcc
    30061 attggaatat gaaaaggttt caaagttatt aactaagtac gcaattccta gtattatagc
    30121 aatgttagta agtgctttat ataacattgt tgaccaaata tttattgggc aaggtgttgg
    30181 tgtattgggc aatgctgcta caaatgtcac ttttccacta acaacaatat gtactgcaat
    30241 tgcattattg ttaggaattg gaggagcgtc taagtgttca ttggaattag gtgctaaaaa
    30301 ttcagaaaaa gctacaaaag cagcaggaaa ttctatatgc ttgatggctg tttttggaat
    30361 aagtttattt atagtagtat caatattttt aacaccacta ttaaaattct ttggctctac
    30421 atcagaaata ctaccttatg cacacacata tacaaaaatt acatcaattg gattaccatt
    30481 tcttataatg tccactggaa tgagtaagtt gatacttgca gatgggagac cgaaagcttc
    30541 tatgttttgt atgttaatag gagcagttat taatacaatt ttgaatccat tattcatttt
    30601 tgtttttaat atgggaattg ctgggtctgc tttagcaact gttattgggc aacttatatc
    30661 ttttggaata agtgttcatt atataaagaa ttttcaacat attaaattac ataagaaaag
    30721 ttttaaatta gatagtataa tttataaaca tatatttgcg ctaggttcaa gctcatgttt
    30781 taatcaatta gcaatgactg taacacagat agttatgaat aatacattgg catattatgg
    30841 ggctaggtca gtttatggaa gtgagattcc acttgcttgt gtcggtatca ttattaaagt
    30901 aaatatgatt tttatatcta taattattgg tatatcacaa ggtatgcaac caattatagg
    30961 gtataattat ggggctgaaa agtataatcg tgtaaaagaa gcatataagt ttgcagtggg
    31021 aagtgcaact attatatctg ttattgcatt cttatgtttc caattattcc caagacaaat
    31081 tacgtctata tttggtaacg gaaatgagac ttattttata tttgcagaac attattttag
    31141 aactttcttg ttcttaacat ttataaatgg tgttcaaata gtatcatcaa ctttctttac
    31201 atcaattggg aaatcagtgt tgggactttt tacttctttg actcgtcaaa ttttattttt
    31261 aattccattg atagtaattt taccaatgtt tatgggaatt gatggagtaa tgtttgcagg
    31321 accaatagca gatgcagcag cggcaatggt atgtatatac tttgcagttc atgaaatgaa
    31381 atcattgact ataaagcaaa ataatttgat gagtaaccat aataagattg cagaggtata
    31441 agacaatatt taagaagtat agaaaattaa tttaaagaag tataataaac taatttagga
    31501 agtatagaaa attaatctaa agaagtataa taaactaatt tagaaagtat agaaaattaa
    31561 tctaaagaag tgtaataaac taatttagga agtatagaaa attaatctaa agaagtgtaa
    31621 taaactaatt taggaagtat agaaaattaa tttaaagaag tataataaac taatttagga
    31681 agtatagaaa attaatttaa agaagtataa taaactaatt caggaagtat agaaagctaa
    31741 tctaaagaag tatagtaaac taatttagga agtatagaaa attaatctaa agaagtataa
    31801 taaactaatt taagaaatat agaaaattaa tttaaagaaa tacaatacat taatttttaa
    31861 gtaacattaa attaatgtaa gtaaaataat gttcatatga agatttaaag gtgcattttc
    31921 tgaagctaag tatatgttgt agagtgttag gtctctctat cctgtgaagt ttaatagctc
    31981 aagaaaatgc actatttatg atgattattt tgttttattt ccaattttgg aaataactat
    32041 tctaattaaa tctaaaatta taccataaat aagaaaagaa agtatagatg ctatgtacca
    32101 ataaatcgaa attgaccctg taattgttct acatgggatt tgcatacctg aatccataaa
    32161 aacaaaaaaa ctatcaactc tggaaataat agacaaaata ggatttaaac ctattagaac
    32221 aatacttttt gagtcttgac caatttgatg catataaatc tcaaataatg caattaaaaa
    32281 aaaccaaaat gtaaaagatt taataatttt tttcatcaaa atacctcaca taatataaat
    32341 tctgtttgca ctatttgctt actacaacta tttatctcca ttcagtcaca tcacttaatt
    32401 gtaatctagg tcttcttgat ggttcttcat caggataacc caaagatatt gctgccacta
    32461 attgactatc tgtatttaac cattcacata attcacgata tgcaaagtat acatcacaaa
    32521 tccaaagact acctagacct aattccacag ctgtaagcga catattctga attgcagctc
    32581 caattgattg catgtttgcc atttcataga atcgttcttc aggggatagc ttttctaaag
    32641 gtgatttacc taatatattt aaaataaaaa ttgttactgg agcttgtttc atgatttcaa
    32701 ctgtgtaatt tgcaccagcg atatgttgac gacttcctgg aagaagccca ttatcattaa
    32761 tttcattttg aatacctttg ctcatggctt taagcataga ttctttttcc ttttcagtga
    32821 tgacaacaaa acgccatggt tgcctgtttt tagatgaagg tgcatttatt ccagcttcaa
    32881 ttattttctc tatagtttca tgtgaaatgc tttgattttt atattttctg atacttcgtc
    32941 tttttgatat agaatcactt atcattttaa gtaacctccg tttatttttt ggaaaaatct
    33001 atttaatttt tattttctat tttaattatt ttagcattaa tcagaaaaaa agtcattgat
    33061 tttagtatac aattattaat gattatatta agaattgtat caaaaagtat gtgattatac
    33121 taagggatta tattaaacat tatatttaaa attgtatgaa aggttgtatt taatattata
    33181 ttgagagata tatatattag gatttatata tattcagatt tattattata ttgagcctta
    33241 tattaaatta aggactataa tttgaaaata agctataaaa acttaatatt gttttgttca
    33301 gagataaaaa aagaatactt taggtgattt ttattaaaaa ttaagagtga taaaattata
    33361 tactttataa atgtaaatat gacgaataaa aatgataaat ataataatat atatatttac
    33421 attaggagtt ttctatacta taattattta aaactaaata taaatgttgg aattatttag
    33481 gacttgaaat tgtctaaaaa taaatacaag tgatgaagag gtgatgtgat gagattagat
    33541 atggatagta tgttatatgt actaatttat atgacattat tggtatctat cattggaagt
    33601 atattttatt tttgtaaaga cctcttaaat cataaaatta agtatgtttt aataagagac
    33661 atatttgtaa atagaattac
//
LOCUS       DAEPKC010000036        32559 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.036, whole genome shotgun sequence.
ACCESSION   DAEPKC010000036 DAEPKC010000000
VERSION     DAEPKC010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 32559)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32559)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32559
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.036"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            192..1406
                     /locus_tag="KR294_001763"
     CDS             192..1406
                     /locus_tag="KR294_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0239843.1"
                     /translation="MQIKIGKVIQCLRKERNLTQEQLAKFIGVSTPAVSKWESGNSYP
                     DIELLPLLADFFNVSIDKLLNYKIDLSEEEVMKIYKELESGFARIEIDLSTEEPKEEF
                     RQDLESVKKLSNMYIEKYPKSYLLKLRICSLYQMYSYKFGKSELNDRVKETMNILEDI
                     VRNTDDIQIKETALIILSNAYCMLEDYEKAELYLNMIHKSIGDTSVNLAMIYLKQNRL
                     EEAEILLQNKLFSNVFNISMDCKGIINVYKNQYKELKKKLENRNFNKNAIEREMEYIK
                     NKLLGYANLSLEIKKMLSEDKGAFFSMYMDYMELSLIFLFFNMKEEAKKALYSLKEIL
                     EKYPIHESLDVSQMRFFDKVESKNLYTFNIYTNLLIVLNDDSYNELREEPIFKDVIEK
                     ILDMEKMLKNKE"
     gene            complement(1826..2347)
                     /locus_tag="KR294_001764"
     CDS             complement(1826..2347)
                     /locus_tag="KR294_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH0239844.1"
                     /translation="MKFKRLRTSENKLCYKAMELYKISFPFHEQRKSSLQEEILKNKE
                     YQFNLIYDKNQFVGIILCWETDDFIYVEHFCIFPEMRNNRYGQRALELLNKKGKTIIL
                     EIDLPIDEISIYRKAFYERVKYKTNNYEHIHPPYHEKFNGHNLIVMSYPEKLSKMEYD
                     KFNHYLRNNVMSF"
     gene            2703..3500
                     /locus_tag="KR294_001765"
     CDS             2703..3500
                     /locus_tag="KR294_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HBH0239845.1"
                     /translation="MEKREKRIIISSLLSVSILMGLVSIYSILNKEDIILTVKGQEQK
                     VSSFKKTVEELLDEQGIKYNSEDKINPSLDTELKDDMKIKVVKVTKSKKEEIEKIPFD
                     TKHVNDSNLLKGKSKVYQEGQEGEKKLVYNLTYHDGKLVKKVLSKEVISKEPTTKIIK
                     YGTKEKVLIASRGANIRGGKHMKVVATAYAGDTITSTGTTPRWGVIAVDPRVIPYGTK
                     VYIPKLGMTFVAEDCGGAIKGNRIDIFMNSEGKASNWGRKSIDIYLH"
     gene            3610..4200
                     /locus_tag="KR294_001766"
     CDS             3610..4200
                     /locus_tag="KR294_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HBH0239846.1"
                     /translation="MKIVCLGDSLTYGFGVSRSNSWTNIVNKETRLEIVNKGINGDTT
                     SGMLARFNEDVVKNSPDIVFIMGGTNDFIAGAGNEIINSNIMAMVHQSYSKNIIPIIG
                     IPLKPDIPNVREDWSCFTDFNIVSQNLESYSYWIKKFCMTFNTNFVDFYSEYNKNMEL
                     EGYKKLYFDGLHPTKEGHRIMADIFINSINKYIEEL"
     gene            4266..5963
                     /locus_tag="KR294_001767"
     CDS             4266..5963
                     /locus_tag="KR294_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HBH0239847.1"
                     /translation="MDYTKTYEEWIKGSYFDEDTKLELENIKNNEKEIEDRFYKDLEF
                     GTAGLRGIIEAGTNRINKYTVRRATFGLANYILENTTKEETSRGVVIAHDNRHKSRQF
                     CIESANTLAACGIKAYIFDSLRTTPELSFAVRSLNAIAGIVITASHNPPEYNGYKVYW
                     EDGAQVMPEIANAITEKVNSIHDYSTIPTLTEANKNLVVLLDESQDTKFIEAVKSQII
                     RKDLVKNVGKSFKIVYTPLCGTGNVPIRRALKEVGFENIIVVPEEENPDPNFAGLDYP
                     NPEEKKALNRGILLAKEKGADLVIATDPDCDRVGVAVKTTTGEYALLTGNQIGGMLTH
                     YIIEGLKENNKLKENPTIIKTIVTSEFGADIAKANNVDVLNVLTGFKFIGEKIKLFEQ
                     NKNRSYVFGYEESYGYLVGTHARDKDGVVSSLLISEMAAFYYSKGMSLYDGLIELYKK
                     YGFFKEQTISLTLKGIEGVEKIKEIISYFRENQIDYINSIKVVDKKDYKNGIDNLPKS
                     DVLKYFLEDESWVAIRPSGTEPKLKFYIAVKGASDIEADKKIQGLKKYIDDMVEKLK"
     gene            6177..7016
                     /locus_tag="KR294_001768"
     CDS             6177..7016
                     /locus_tag="KR294_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HBH0239848.1"
                     /translation="MFGIDKKLIEYIIAKSNYSELSSKSAEVSFFLMLSIFPFLIFTI
                     SSIAYIPILHLNKYIALFRNMMPEGAFAVLSSIIVSAIDNRNLKFLAVSFVLTMWTFS
                     RAVKALIKGMNRAYKVKETRSFFKILSISFLFTIMLLVLIFLSMIFLVYGEKIGYFIF
                     NLVGLDEIFIKIWDILRYTVGIITIIVIFTLLYKYTPNKKLTIKESAPGAIFATFAWF
                     LVSFLYSYYTNYYANYEVIYGSIAEIIVLMTWMYFSSWSIVIGYEVNSRLYFRKIRHE
                     MLK"
     gene            7533..9389
                     /locus_tag="KR294_001769"
     CDS             7533..9389
                     /locus_tag="KR294_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing protein"
                     /protein_id="HBH0239849.1"
                     /translation="MDTHNKYVNFIKNIPVPFLYCRIVKRQEDIEYRVEYISKGMGKV
                     LQLEEGICDKNILDVLPVFKSKKYFKELFSNEVDCIKRYIPTLKNWINIKKQIIGDSY
                     IILYFGKIVFDYRQIIDSFDKKEKVAYIKDEEGIYIDCSENLIPILNNNIKTTKDIFG
                     KNDIEVWGENTGKLFRDDYREGVSSKKRFLQNLFEYEETFFMVEKYFLYDEDELLGTI
                     GIVDNIIYSGYSNRNYNSKDLMKMIEHSIPENMFYKDVYGNYIGFNSGFLNLACMNKE
                     ELLGKNSYKISEEEALIDKIFESDKGVVENKKVVTFELNISMNDENKCIEITKRPFFD
                     SYGSVIGIIGTARDISRRKRLEEEMDKTRMEFFANLSHELRTPINLISSSLQVIEKKE
                     ADLIESNDTLKRNLGIIKQNGNRILRLVNNVIDFTKMQSGYLDFKPEESDIIAFIEEI
                     CMSVADFASQNNIQLTFDTEIEEFSMLFDSEKLERIILNLLSNGIKYNKKDGKINIFL
                     YVKDNVFNMKISDSGIGIPKEKIDKIFNRFEQIDNELSYRVKGSGIGLSLVKSLVELH
                     EGSISLKSQLGIGSEFIVSLPVRSKNNIEKYNHKREISNELSKKLEIEFSDL"
     misc_binding    9472..9712
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    9778..10013
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            10098..11315
                     /locus_tag="KR294_001770"
     CDS             10098..11315
                     /locus_tag="KR294_001770"
                     /EC_number="1.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HBH0239850.1"
                     /translation="MENKVKIGVLGYGVVGSGLIDIIDNNKEKRNIEIVGILVNNLEK
                     HKDKKYSNIITNNIDDIFNKDIDILVEVMGGLEPSLSYIKKALNNKIHVVTANKDLLA
                     ECGDELAKLASENKVSIKFEASVAGGIPVLKPIIESLEGNNIDSINAILNGTTNFILS
                     KMYDENLSYDMALRQAQELGFAEANPESDVLGYDAARKLSILSTLAYDNRVYWKDVYL
                     EGITDIDEKDIEYAKKLNCKIKLIGQSKYENDKVSAFVRPVLVEKDNILARIDNEFNA
                     VIVNGDSVGEVSFVGKGAGSLATGSAVYSDVIDIIDNRVSSIDSFTKDKIQVNKIVRE
                     KCGALLRFKKCNKDEILNIVENCLVKFDILNDDDELAIMVYADSEYEINNSLCLIKDK
                     GYCEKMNKMLKIS"
     gene            11432..11926
                     /gene="cdeM"
                     /locus_tag="KR294_001771"
     CDS             11432..11926
                     /gene="cdeM"
                     /locus_tag="KR294_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exosporium morphogenetic protein CdeM"
                     /protein_id="HBH0239851.1"
                     /translation="MENKKYANGGYSEDWYERGESTAKWFQNDREEYERAAYDEDRER
                     RGSNCGCSDSGENRPRNCERFRREAEIREREAREAFCESSERKKEALAYECEARKLWE
                     EAEKYWDEYSKYNYKGIEYLAEAARLFDEGMECEARRNGNNGGNNNNCCHKCHKCNCN
                     CCRK"
     gene            12191..13456
                     /gene="hisD"
                     /locus_tag="KR294_001772"
     CDS             12191..13456
                     /gene="hisD"
                     /locus_tag="KR294_001772"
                     /EC_number="1.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol dehydrogenase"
                     /protein_id="HBH0239852.1"
                     /translation="MKSIKTSSMKEKVDEKILREQVSSIIEDIRNNKDVALKKYNEKF
                     DRNTRDEFRITKEEIKEAYKHVDDEFINNLKIAAKNIREFAKAQKLSFENPFEKEIYP
                     GVILGQTNIPIESCLAYVPGGQYPLFSTALMLIIPAKVAGVKRIVACSPTMKNTEKIN
                     PKTLVAMDIAGADEIYATGGVQAIAAFTYGTEKINPVDIIVGPGNKFVTEAKRQCYGQ
                     VGIDFVAGPSEVLIIADETSNPVYIAADLLAQCEHDLNARGILLTNSLEVAQKVEKNI
                     ESMLKDLPTKDIAYSSWENNGEIILVDDMEEAIKISNFYAPEHLEVAVNEYNDICDRL
                     TNYGSLFIGNLSAEVFGDYVSGTNHTLPTLKASRYTGGVWVGTFIKTCTKQIFNEKAI
                     QSLAPVAEKLAKEEGLYAHAKAAEVRFKK"
     gene            complement(13659..14411)
                     /locus_tag="KR294_001773"
     CDS             complement(13659..14411)
                     /locus_tag="KR294_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBH0239853.1"
                     /translation="MSYFQYQGNSCFYKEYGQGKPIIFLHGNTGSSNMFKALVPLYVE
                     NFRCILIDFLGNGQSDRVSQFSPDIWHDEALQTIALIEHLNCGKVGLIGTSGGAWAAV
                     NTGLERPDLVEAIIADSFDGRTLNDNFIDNLITGREKSKQDIQARKFYEWCHGKDWEN
                     VVNLDTKALLQCANEKRPLFHKELCKLEMPILFTGSKEDEMCRHNLEEEYKQMATFIS
                     KASIHIFSQGGHPAILTNADEFAQLAKVFFKY"
     gene            complement(14529..14798)
                     /locus_tag="KR294_001774"
     CDS             complement(14529..14798)
                     /locus_tag="KR294_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239854.1"
                     /translation="MSYQNSIDLLPKELIEQVQEYIDGKVIYIPKKQEHKKHWGENTN
                     TKQVLASRNSQICINFQNGMSIKQLSEKYFLTEKSIQRILKQQNL"
     gene            15273..16367
                     /locus_tag="KR294_001775"
     CDS             15273..16367
                     /locus_tag="KR294_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBH0239855.1"
                     /translation="MKNIVGKPQTIKKVNEDLIKNIIKNEGPITKPEISNITELSLAT
                     VNKIVEQLALKNEVKVSGLSESTGGRRAQLFEINANLEHIIALYYYRNCCIGVVANLL
                     GEIIYQEEFNIRMDTYENVNQDTFFVIDTLIKKEKGNNIRAIGIGVPGVVKKGVVKNI
                     PTIKSWEGINLENLIKSKYNTKVFIENDTNITTIGIYQKQYKDKYKNMALMYLEDGIG
                     SGIVINGELYLGSTNFAGELSYLNIEFGKYNSNNLNLEDYIMSLRKRYLESKDNKFKK
                     EILSIISNFIRTLVCVLNPQAMIIQCSILTKSDMEFIEKDVSNNVGEENFPKLIKVES
                     LREGSINGVISMCLKETDYQYSLSNKKGGY"
     gene            16369..17319
                     /locus_tag="KR294_001776"
     CDS             16369..17319
                     /locus_tag="KR294_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine kinase"
                     /protein_id="HBH0239856.1"
                     /translation="MKYLVSIDGGGTKTKFCVSDLDGNILKEHTTGSTNYKSVGIKKT
                     YENINNGFKKILKDLYIDYDDIEYTVFGISGCDSPNDYKIIMDEILKIGINKEKIYLA
                     NDAVLAFYAQADSPGLVIVAGTGSIILGIKEDGEIYRVGGWGYNFSDLGSGYDIGRKL
                     LKKVLLYCDECHEYSDLFSCVLDFFGANSFEQLAYMITDINNNVEIANLASLVIDCAE
                     QGDKLAIEILRESSTELSKLAQVILRKISNPMKVDKSEINIVLSGGTLNKTVYAQMLM
                     NNLKTENTDKNLKFISQENQPVYGGIRLAMALANRRVKHG"
     gene            17312..18496
                     /locus_tag="KR294_001777"
     CDS             17312..18496
                     /locus_tag="KR294_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239857.1"
                     /translation="MDRKKVIVQIFTGGFKAKEIKFNDIKCKLLELLDCIDIEKVIMG
                     WSVDEELYVETKKLLNKYNVELYLWLPCFSEIGLLEKSNLLIDYMGKEVKGYALQEDE
                     NFEFYCPNNKENIKNIKKIYSTYFSDIKFDGIFLDKIRYGSFSNKLNGVFNCFCKDCL
                     NIYEKNNIDKESLMREMNNVSKGVIDNEDTPFGITEYINGKYKFKNKIWEDFFETKNQ
                     NIYKALLEISNYFKSKGLKIGIDTFSPFISYFTGQDLEKLQEVADFIKPMMYRTTKAP
                     AGLPFEFERFIDESIHKNKEIGKRNFLDILGIKEYEGDVYPIEFVLEEIDFMTRNLNK
                     DIYVGVEINKKEIISPVTPKYISENISNINKTTVKGYVLSWDLLSAPKENIDEIIKWF
                     RN"
     gene            18509..20005
                     /locus_tag="KR294_001778"
     CDS             18509..20005
                     /locus_tag="KR294_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HBH0239858.1"
                     /translation="MSKILEMQQIYKSFGKVDVLKGINFELEKGEVRALLGANGAGKS
                     TLIKILGGVHSQTKGKVILTGNEIMFKNPHHSKENGISIIYQELSLIPTLTVLENIFL
                     GREILKGSVFLNKKDMLEECMKICEDFDFNIDPHMVVSNLSVANQQMVEIMKAVSCNS
                     EIIIMDEPTTSLTNNEKDGLFKIISRLKSKGKTIVYISHILEEVFKVCDSASIMKNGI
                     MIGTYDVEDLTKLKITQLMTGNDNHKLIEKKDYTFAKYEEPPVLEVKNISWSNKIKNV
                     SFKVYRGEVVGLAGLVGSRRTEIINLIFGIDNKDSGDIFINGKKVDITSPKVAIKNKI
                     GLIPEDRKNLGLILEQAIYTNSSSVQIDKFKKFLFIDRNKEIEFSKKGVKELGIKVND
                     VKQEVKELSGGNQQKVVVSKWLEKDLDLIIYDEPTKGIDIAAKEDIFNTIKEFSSKGI
                     GVIFISSDLEEVIRVSDRILVTREGSIVDDLKNENIQVQDIMNSIFNV"
     gene            20028..20978
                     /locus_tag="KR294_001779"
     CDS             20028..20978
                     /locus_tag="KR294_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0239859.1"
                     /translation="MKKAFEKLNLRDYGVLLGFLALCIAISIATPSFLGKQNILNLLR
                     QSSIIGIISAGMTFVIISGNFDISVGAVAALAGAITMKFATGGTNLFASMLLGVAICA
                     VIGLINGIVVAKINVPSLIATMAMVTIVRGLLLMLTGGYPITENIPILDYIGNGYLFN
                     IPIPVVIFFIVVLASFIVLNKTKFGRYVYSVGGNQEASKLNGINVDSHKVKVFIINAV
                     LAGIAGIVLTGRLGTATAIAGEGYDMDAIASVVIGGTSVAGGSGSVLKTVIGVLLMSV
                     INNSFNLLGIDVYFQYIFKGLIILAAVGFDSYSKKKLASR"
     gene            20999..21961
                     /locus_tag="KR294_001780"
     CDS             20999..21961
                     /locus_tag="KR294_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HBH0239860.1"
                     /translation="MKKLMKHLALLLSLVMIFGLVGCSNGGDKEKNGEKKIAVLLPGS
                     TGYFVATKQGIDAKSKELGVSVEYADAQWDASKQLSQAEDFMAKGVDMIALCGVDSAV
                     SERIVKAANDSDVPIVAFTNSIGSNPTGEFKGLVTYIGQNEEETGALTGKIAKNLLGE
                     TGGKAVLIEGVPGTTPQVLRKKGLEKELKDSNIEIVYNQTSNWEKEQALKVTEDLIQK
                     KTDFNVIICQDDNSATGAGQALKDAGLKDKVKVIGLGGSKDGLKAITDGLIDGTTYMS
                     AVEEGGLVIEKASKFLKGEKIEPVTQIKQVEVNKDNISEFKGEW"
     gene            22333..22965
                     /locus_tag="KR294_001781"
     CDS             22333..22965
                     /locus_tag="KR294_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBH0239861.1"
                     /translation="MARRLFLERIGLIFLGSAILAFGVYNFYYLNNITEGGVLGILLL
                     LKNLFNIQPAIANVVIDGLLLLVGYKFFGKKFLIYSIVASITFSVLYDLFEAIGPLVP
                     QSQNMLLSTILAGVTVGTGVGIVVKAGCASGGDDALALVISKTTSLNIGQVYLATDVI
                     VLLLSLFYLSAFDIFYSLIAVTISGKVIDFIYYHGKSLDMDISNDIVPEC"
     gene            23376..23468
                     /gene="kdpF"
                     /locus_tag="KR294_001782"
     CDS             23376..23468
                     /gene="kdpF"
                     /locus_tag="KR294_001782"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: protein motif:HMM:TIGR02115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="K(+)-transporting ATPase subunit F"
                     /protein_id="HBH0239862.1"
                     /translation="MEGLPMWFLAVVIIMLIIYLVYALINPEKF"
     gene            23509..25191
                     /gene="kdpA"
                     /locus_tag="KR294_001783"
     CDS             23509..25191
                     /gene="kdpA"
                     /locus_tag="KR294_001783"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015391009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit KdpA"
                     /protein_id="HBH0239863.1"
                     /translation="MFMVQIVIVLAIFMILVIPMGKYLYHIATNQKTFGDRLFDKVDN
                     FIYKVCSIDKKKEMNWKQYALALLFTNAVMVFIGYIILRTQSMHIFNPSGIKSMEQGL
                     SFNTIISFMTNTNLQHYSGESGLSYFSQMTVIIYMMFTSAATGYAAAMAFVRGLVGKK
                     KTLGNFYVDLIRITTRVLLPGALIIGLILVTQGVPQTFAGTETVTTIEGKLQDIARGP
                     VAALESIKHLGTNGGGFFGSNSSHPFENPTIISNIVEILSMMILPGACVVAFGHMIKN
                     KKQGWVVFGAMSIIFLIGLVVCFKAESAGNPILSQLGLNQSMGSMEGKEVRFGIAQSS
                     LFTTVTTSFTTGTVNNMHDTLTPLGGLVPLLNMMLNVVFGGKGVGLMNMLMYAIIAVF
                     LCGLMVGRTPEFLTKKIEGKEMKLIALLIILHPLLILMFSGLSVAIPAGLEGISNPGF
                     HGLSQVLYEFASSAANNGSGFEGLGDNTMFWNITTGIVMFFGRYVSIIVLLAISSLLA
                     SKKAVNESIGTLRTDNFTFTIVLVLVVLIVGALTFFPALALGPISEHLVLWH"
     gene            25216..27273
                     /gene="kdpB"
                     /locus_tag="KR294_001784"
     CDS             25216..27273
                     /gene="kdpB"
                     /locus_tag="KR294_001784"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010966942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit KdpB"
                     /protein_id="HBH0239864.1"
                     /translation="METKKTKFITKDIFKTSIIEAFKKLNPKYMMKNPVMFVVEIGFI
                     VTLILTIVPSLFGDEGNNLRAYNGIVTIILFITVLFANFAEAVAEGRGKAQADTLKKT
                     RKDTVARVIDTLGNEKMISASELKLGDIVLVNAGEVIPNDGEVIEGIASVDESAITGE
                     SAPVMRESGGDFASVTGGTTVVSDWLKIRITTKPGESFLDKMIALVEGASRQKTPNEI
                     ALNTLLVGLTLIFMVVLISLYPMANYAGVKIPISTMIALLVCLIPTTIGGLLSAIGIA
                     GMDRVTRFNVIAMSGKAVEACGDVDTMILDKTGTITYGNRLASEFIAVGNADSKDLIN
                     YSVMCSLKDDTPEGKSIVDLGMKLGSTGKTKEAEEAEFVEFSAQTRMSGINLADGRAI
                     RKGAYDSIIKRVKESGGTVPEDLEENVNRVAKLGGTPLVVCVDNEIYGIIYLKDTVKS
                     GLVERFARLREIGIKTIMCTGDNPLTAATIAREAGVDGFIAECKPEDKIDAIKKEQLE
                     GKIVAMTGDGTNDAPALAQADVGLAMNSGTTSAKEAANMVDLDSDPTKILEVVEIGKQ
                     LLITRGALTTFSIANDVAKYFAIIPAIFTLAIPQMEILNVMKLSTSFSAILSALIFNA
                     IIIPCLIPLAMKGVKYRPMKSQAMLMRNMLIFGLGGVIVPFLGIKLIDLLITPLVMVL
                     NLG"
     gene            27292..27918
                     /locus_tag="KR294_001785"
     CDS             27292..27918
                     /locus_tag="KR294_001785"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="K(+)-transporting ATPase subunit C"
                     /protein_id="HBH0239865.1"
                     /translation="MKTLKPALLVSIVLLVVCGLVYPLVLTGVSQVAFKDKANGSMIE
                     VNGVKVGSELIGQSFTDARFFKGRVSSVNYNTYTKEDLVPDKDGNTSYGGVSSGSFNY
                     GATNPELHDRVQKDIEQFLKDNPTVKREDIPTDLLTASGSGLDPNISPASAKIQIPAI
                     AKASGISESKLQKIVEDNTSKKLFGVLGEDRVNVLKVNVEVAKILGLI"
     gene            28155..29063
                     /gene="cysK"
                     /locus_tag="KR294_001786"
     CDS             28155..29063
                     /gene="cysK"
                     /locus_tag="KR294_001786"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HBH0239866.1"
                     /translation="MLYNNALELIGNTPVVRLNNLGCTNGCSNIYVKLEKVNPAGSIK
                     DRAVYEMLEGLEQRGELKKGDVLVEATSGNTGIALSMIGKLKGYEVVIVMPETMSVER
                     RDLMKAYGANLVLTDGKAGMAGSIEKANELLKENPNYKSLKQFENKDNPNAHYKTTAV
                     EIMNDVKDLDIFVCGVGTGGTLIGTARYLKEQNPNIRVIALEPKKSPAISENKTGPHK
                     IQGIGANFVPENYDSSVVDEVILVDDEDAFDTVKLLAAKEGILVGISSGANIFGAIEM
                     AKKYPDKKIVTVAPDGVDKYMSMGIF"
     gene            29090..29680
                     /gene="cysE"
                     /locus_tag="KR294_001787"
     CDS             29090..29680
                     /gene="cysE"
                     /locus_tag="KR294_001787"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HBH0239867.1"
                     /translation="MFKKINKDIEYIMKNDPAARSKIEVFLLYPSVHAMIMHRMAHAL
                     YKKKKLFTARLISQISRFMTGIEIHPGAKMGEGILIDHGMGVVIGETAEVGNRVTIYQ
                     GATLGATGKDTGKRHPTVGDDVLIGAGTKILGPLNIGSNSKIGANSVVVKDVPNGATV
                     VGIPAKIVKIRNLEPVKKNKKEVSYEYDELDNVYYI"
     gene            29840..30028
                     /locus_tag="KR294_001788"
     CDS             29840..30028
                     /locus_tag="KR294_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HBH0239868.1"
                     /translation="MKANVNQDTCIGCGLCPSICPEVFDMKDDGKSHVIVDEVPSDAE
                     ESAAEARESCPVDAIDVH"
     gene            complement(30082..30951)
                     /locus_tag="KR294_001789"
     CDS             complement(30082..30951)
                     /locus_tag="KR294_001789"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HBH0239869.1"
                     /translation="MKLNRNDSCWCGSTKKYKKCHMDMDNKIDSFAKLGHIVPTHDII
                     KNESQIEEIKKSAVINTKILDYISDKIEIGMSTEDINKLVHDFTLQNGAIPAPLDYNG
                     FPKSVCTSVNNEVCHGIPSKDIILKDGDIINVDVSTIFNGYYSDASRMFMIGNVNENA
                     KKLVQVTKECVQKGLEVAKPWGFLGDIGDVINSYAKKNGYSVVREIGGHGVGLSFHED
                     PFVSYVSKKGTEMLLVPGMIFTIEPMVNEGTHEIFVDEENNWTIYTKDGKLSAQWECM
                     VLVTETGVEILTE"
     gene            complement(31148..32392)
                     /locus_tag="KR294_001790"
     CDS             complement(31148..32392)
                     /locus_tag="KR294_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239870.1"
                     /translation="MENNLNTAKRNNTELLQNDSLKVNLQIGVDFTLLSKSLKAFYKK
                     EKDFYCIALAPCNVSSEKANRKISIYNMIKEINILIESITDKNELLSEELFTNNLSEF
                     YDESLDEIYIDLKQAYLYIKKNTDSLNIEDSIEYVFDVDISNDIKAKENPLINFNSLS
                     LVVWSGETKHILQQMNILDLEDIHSYSIENNTNITIYENNTLQYKFDEESENIKDSSI
                     DIIEQMLILPDDLNYDKDEVENMKNRLAKINIKYLQTLKEKDIKIKLINSNLTDEPEF
                     SDLKYQLPPCWVRSGKTWKDVPGIYRNNSIVAKIGYSNPSYANVHSSKNLELHETAHA
                     IDKNVLNKKSNSEEFMEVFAQERYKLYDPKQVAHAYISKFIEEFFAESFVHYYLDEDS
                     KNTLKENCPLTYDFLEKLELNY"
BASE COUNT        12626 a         3417 c         5752 g        10764 t
ORIGIN      
        1 tgtgaatcta ttaattaggt tatacttaaa cttaattaat agattttata tttcaagcca
       61 atgagatagg gttttagatt aaaatataac caatggttaa attacagaca ttttgttaac
      121 tttccctcga tttactagta aatatttttt ttatatactt aaattacaac agatgtacta
      181 gggaggtata tatgcaaatt aaaataggta aagtcataca gtgtcttaga aaagaacgaa
      241 atttaactca agaacaatta gcaaagttta taggtgtgtc aacaccagca gtatctaagt
      301 gggagagtgg aaattcttac ccagatatag aattattgcc tttattagca gactttttta
      361 atgtgtctat tgataagctt ttaaattaca agattgattt aagtgaagaa gaagtaatga
      421 aaatttataa agaattagaa tcaggctttg ctagaattga aattgattta tcaacagaag
      481 aaccaaaaga agaatttaga caagacttag aatctgtaaa aaagctttcc aatatgtata
      541 tagagaagta tcctaaaagc tatttattga agctaaggat atgttcgctg tatcagatgt
      601 attcatataa atttggtaag agtgaactta atgacagagt aaaagaaaca atgaatattc
      661 ttgaagatat agtgagaaat acagatgata tccaaataaa agaaacagct cttattatat
      721 tatcaaacgc atattgtatg ttggaggatt atgaaaaggc agagttgtat ttaaatatga
      781 tacataagtc aataggggat acaagtgtta atttagctat gatatattta aagcaaaata
      841 gacttgaaga agcagaaata ttgcttcaaa ataaattgtt tagtaatgta tttaatataa
      901 gcatggattg taagggaata attaatgtat acaaaaatca atacaaggaa ttaaagaaaa
      961 aattggagaa tagaaatttt aataaaaatg caattgagag agaaatggag tatataaaaa
     1021 ataagttgct ggggtatgca aatctttctt tagaaataaa aaaaatgctc agtgaagata
     1081 aaggtgcatt ttttagtatg tatatggatt atatggaatt atctctaatt tttttatttt
     1141 ttaacatgaa agaagaagca aaaaaagcct tatatagtct aaaagaaata ttagaaaaat
     1201 atcctataca tgaaagtttg gatgtaagtc aaatgagatt ttttgataag gtagagtcta
     1261 aaaatttata tacttttaat atatatacaa acttgttaat tgtacttaat gatgatagtt
     1321 ataatgagct tagagaagaa ccaattttta aggatgtaat tgaaaagatt ttagatatgg
     1381 aaaaaatgtt gaaaaataaa gaataagtaa aaatttaata taggacttaa agattaatca
     1441 aattaaaaga aagtgtttca aaataaaaat ttgaatcacc ttttttgtcg gtcttaaaca
     1501 gttatttaga aaaatagagg tttcaaaata gaaatctgaa ttatctgtat tattacacaa
     1561 aaatagaaac ctaaatttat aaaaatagaa taaagtttgt tatataaaat gtaattttgt
     1621 ctataaaatc tcacttgttt tcttaacttt aagcgtgaaa aagagaatgt atcatgaatt
     1681 ttttagttca tgatgcatcc ttctttgtat gaaatccaat atatctttat tatttaaaca
     1741 atggaaaaga gccttatttc tattttgaga catctctttt atttaattat gaagttttat
     1801 acagttcaat aaataggaat tatatttaga aactcatgac attatttctt agatagtgat
     1861 taaatttatc atattccatt ttagataact tttctgggta agacattaca atcaggttat
     1921 gcccattaaa tttttcatgg tatggtggat gaatgtgttc ataattattt gtcttatatt
     1981 ttactctttc atagaacgcc ttgcgataaa ttgaaatctc atcaattgga aggtcaattt
     2041 ctaaaataat agtttttcct ttcttattta aaagctctaa cgctctttgt ccatatctat
     2101 tattgcgcat ttctggaaaa atgcagaaat gttctacata gataaagtca tctgtttccc
     2161 aacataaaat tatgccgaca aactggtttt tatcataaat taaattgaac tgatattctt
     2221 tatttttcaa aatttcttct tgcaaagaag attttctttg ttcatgaaat gggaaactaa
     2281 ttttatataa ttccatagcc ttgtaacata atttattttc actggttctt aaccgtttaa
     2341 atttcacttt actcctccta atcacgaaaa ttccaattta tttatgagtt cattttacca
     2401 tagtcagtat ttgcatacaa tgtgttttaa gttgagtgtc atttctttct tttatttatg
     2461 cttatatctc atagactaag agataattgc ttaagacata actaaaaact attatattaa
     2521 gctttgataa tctaaaaaca gtatatttat ggacttttct aggtctaaaa gtaatcttaa
     2581 taattttaga agttacaaaa aagttacata aatttggaaa gctataatat acatatataa
     2641 tataaggtta aaactgtaat gaataatatt aatttaaaat ttgaacatgg aaggagatta
     2701 ttatggagaa aagagaaaag aggataataa tatcatcttt attaagtgta tcaattttaa
     2761 tgggtttggt aagtatatat tctatattaa ataaagaaga cataatttta actgttaagg
     2821 gtcaagagca aaaagtatct tcctttaaga aaacagttga ggaacttttg gatgaacagg
     2881 gtataaagta taattctgaa gataagatta atccaagttt agatacagaa ctaaaagatg
     2941 atatgaaaat aaaagttgtt aaggtaacta aaagtaaaaa agaagagatt gaaaaaattc
     3001 catttgatac aaagcatgta aatgatagta atttgttaaa aggaaaatct aaagtttatc
     3061 aagaaggtca agaaggagaa aaaaaactag tctataattt aacttaccat gatggaaagt
     3121 tagtcaaaaa agtcttatca aaagaagtaa tatctaagga gccaactaca aaaattataa
     3181 aatatggaac taaagaaaaa gtactaatag catcaagagg agcaaatata agaggaggca
     3241 aacatatgaa agtggttgcc actgcatatg caggagatac aataacatct actggtacaa
     3301 ctccaagatg gggtgttatt gcagttgacc cacgtgtaat accatatgga acaaaagtat
     3361 atatacctaa actgggtatg acttttgtag cagaagattg tggaggtgca attaaaggta
     3421 atagaataga catttttatg aacagtgaag gaaaagcttc aaattgggga aggaaaagta
     3481 tagatatata tctacattaa attagtgaat agaataactt tacttgaagg acaaaaaagt
     3541 ataaaatatg aattaactaa actgttagat tattcttaaa acataaaaat atatctaagg
     3601 ggggataaga tgaaaatagt atgcttagga gacagtttaa cgtatggatt tggagtatca
     3661 cgaagtaatt catggacaaa cattgtaaat aaagagactc gattagaaat agtaaataag
     3721 ggtataaatg gtgatacaac aagtggtatg ttagctaggt ttaatgaaga tgttgtaaaa
     3781 aattctcctg atatagtttt tataatgggt ggcaccaatg attttattgc tggtgcggga
     3841 aatgaaatta ttaattctaa tataatggct atggtgcatc agtcatattc aaaaaatatt
     3901 atacctataa taggtatacc attaaaacca gatattccaa atgttaggga agattggagt
     3961 tgttttactg attttaatat agtatctcaa aacttagaat catatagtta ttggataaaa
     4021 aaattttgta tgacatttaa tactaatttc gtagattttt attcagaata taataaaaat
     4081 atggaactag aaggatataa aaaattatat tttgatgggt tacatccaac caaagagggt
     4141 catagaataa tggcagacat ttttattaat tcaattaata agtatataga agagttatag
     4201 attacattaa aatgcttgtt tatgcgtcag ttgcaataaa tacatacagt agagaggggt
     4261 ttattatgga ttatactaaa acttatgaag agtggataaa gggttcatat tttgatgaag
     4321 atacaaagct agagttggag aatataaaaa ataatgaaaa agaaatagag gatagattct
     4381 ataaggattt agaatttggg actgcgggtc ttagaggaat aattgaagca ggaacgaata
     4441 gaataaataa gtacacagtt agaagagcta cttttggatt ggcaaactat atattagaaa
     4501 acacaacaaa agaagaaaca agtagaggag tagtaatagc tcatgataat agacacaagt
     4561 ctagacaatt ctgtatagaa tctgcaaata ctttggcagc atgtggtata aaagcatata
     4621 tatttgatag tttgagaact actccagaat tatcttttgc tgttagaagc ttaaatgcaa
     4681 tcgctggtat agtcataaca gcaagccata atcctccaga atataatgga tataaggtat
     4741 actgggaaga tggagcacaa gttatgccag agattgcaaa tgcaataaca gagaaagtaa
     4801 atagtataca tgattatagt acaataccaa ccttaacgga agctaataaa aatttggtag
     4861 ttttgttgga cgaatcacaa gatactaaat ttatagaagc agtgaaaagc caaattataa
     4921 gaaaagattt agttaaaaat gtaggtaaaa gctttaagat agtttataca cctctttgtg
     4981 gaacagggaa tgttccaata agaagagcat tgaaagaagt tggttttgaa aatataattg
     5041 tagttccaga agaagaaaat ccagacccaa attttgcagg gcttgattat ccaaatccag
     5101 aagagaaaaa agctttaaat agaggtatat tactcgcaaa agaaaaagga gcagaccttg
     5161 taatagcaac tgacccagat tgtgatagag taggtgtagc agtaaaaact actacaggtg
     5221 agtatgcttt acttacagga aatcaaattg gtggtatgct gacacattat ataatagaag
     5281 gattaaaaga aaataataaa ttaaaagaaa atcctacaat aataaaaacc atagttacat
     5341 cagaatttgg agcagatata gctaaagcaa ataatgttga tgtattaaat gttcttacag
     5401 gttttaaatt tattggtgaa aaaataaaat tatttgaaca aaataaaaat agaagttatg
     5461 tatttggata tgaagaaagt tatggttact tagttgggac tcatgctaga gataaagatg
     5521 gtgtagtttc ttcattgtta atatctgaaa tggcagcatt ttactattca aaaggtatga
     5581 gtttatatga tggtttaata gaactttata aaaagtatgg atttttcaaa gaacagacta
     5641 tatctttgac tttaaaaggt atagaaggtg tagaaaagat aaaagaaata atatcttatt
     5701 ttagagaaaa tcaaattgat tatataaata gtattaaagt agttgataaa aaagattata
     5761 aaaatggtat agataatctt cctaaatctg atgttttaaa atactttttg gaagatgaat
     5821 cttgggtagc tataagacca tctggaacag aaccaaaact taaattttac atagctgtaa
     5881 aaggagctag tgatattgaa gcagataaaa agattcaagg tttgaaaaag tatatagatg
     5941 acatggtcga aaaattaaaa taaaatatta ttattttata agataatttt gtaataatat
     6001 ttatttagct gaaaattata atttactttc attgagtaga atatggaaat gttagtagaa
     6061 ttgttatttt cagcttttat ttgtgttatt tttacttaaa taattatatt atagaatgaa
     6121 tctgagtata attaatattg tataatgaaa ttaatttgat agaaaagggg atatttatgt
     6181 ttggtataga taagaaattg attgaatata taattgcaaa atccaattac agtgaattaa
     6241 gttcaaagtc agcagaagta tctttcttct taatgttgtc catatttcct tttttaatat
     6301 ttacaataag ttctatagct tatataccga ttcttcattt aaataagtat atagctttgt
     6361 ttagaaatat gatgccagaa ggtgcttttg ctgtgttatc ttcaatcata gtttctgcaa
     6421 tagacaatag aaacctgaaa tttttagcag tcagttttgt acttactatg tggacatttt
     6481 caagagcagt aaaagctctt attaaaggaa tgaatagagc ctataaagtt aaagaaacta
     6541 ggtctttttt taaaatttta tctatatcat ttttatttac aataatgctt ttggtcctta
     6601 tttttttatc tatgatattt ttagtttacg gtgaaaaaat aggttatttt atttttaatc
     6661 ttgtaggatt ggatgagata tttataaaaa tatgggatat tctaagatac actgtaggta
     6721 taataacaat aatagtgata tttacacttt tatataaata cactccaaat aaaaagttaa
     6781 ctattaaaga atctgcgcca ggtgctattt ttgctacttt tgcttggttt ttagtatcat
     6841 ttttatattc ttattataca aattactatg ctaactatga agtaatctat ggaagtatag
     6901 ctgaaataat tgtacttatg acctggatgt attttagtag ttggtctatc gttattggct
     6961 atgaggtaaa ttcaagattg tattttagaa agataagaca tgaaatgtta aagtaaagta
     7021 tttaaaataa aagagagtat ttagtattat aaatgtaatt gaattaataa agaaatattg
     7081 acatttaagt taaaaagtct agaatttttc tgggcttttt ttatttttag tataacttga
     7141 caaattttat ttaatgggat agttttaatt tataatcatc tttaaaaaga tgactattga
     7201 taagtaagag ataaaattgg taagtatcaa aaaatatact aaataaaaat tatagtccta
     7261 atgagttaat ttctgtattt tcaaataatg cagtatttag tcatgtgttt ttatatgcgc
     7321 ctgtatttct aattagcaat atattagaat aagctactgt aattagattt agaaaaaagc
     7381 gacataaata attataaaca aataataaat tacataaaat taaatttatt cacaagtata
     7441 tcttataaaa tatgttataa ttaatagaaa attgtcatat aattaattaa gtagtattat
     7501 tataaataac attgaaaggt agtggttaga atatggatac ccataataaa tatgtaaatt
     7561 ttataaaaaa tatacctgta ccttttttat attgtagaat tgtaaagaga caagaagata
     7621 tagaatatcg agtagaatat ataagtaagg gtatgggcaa agtattacaa ttagaagaag
     7681 gtatttgtga taaaaatata ctagatgtat tgcctgtatt taagtctaaa aaatatttca
     7741 aagagttgtt ctcaaatgaa gtggattgta taaaaaggta cattccgaca cttaaaaact
     7801 ggataaatat aaaaaaacag ataatagggg attcatacat aattttgtat tttggtaaaa
     7861 ttgtatttga ttatagacag ataatcgatt cctttgataa aaaggaaaaa gtagcttata
     7921 ttaaagacga agaaggcata tatatagatt gtagtgaaaa tttaatacca atattaaata
     7981 acaacattaa aacaacgaaa gatatctttg gtaaaaatga tatagaagta tggggagaga
     8041 atacaggaaa attatttaga gatgattata gagaaggagt atctagtaaa aaaagatttt
     8101 tacaaaatct ttttgaatat gaagaaacat tttttatggt tgaaaaatat tttttgtatg
     8161 atgaagacga acttttaggt actataggga tagtagacaa tataatatat agtggttaca
     8221 gtaatagaaa ttataactca aaagatttaa tgaagatgat agaacactca attccagaga
     8281 atatgtttta taaagatgtg tatggaaatt atattggatt taattcaggt tttttgaatt
     8341 tagcttgtat gaataaagaa gaattattag ggaagaatag ttataaaata tcagaagaag
     8401 aagctttaat agataagata tttgaaagtg ataagggtgt agttgaaaat aaaaaagtag
     8461 ttacatttga gttaaatata agtatgaatg atgaaaacaa gtgtattgag attacaaaaa
     8521 ggccgttttt tgatagctat ggaagtgtta ttggaataat tggaacagca agggatataa
     8581 gtagaagaaa aagattagaa gaggaaatgg ataaaactag gatggaattt tttgcaaatt
     8641 tatcccatga acttagaacg cctataaatt taatatcatc ttcattacaa gtgatagaaa
     8701 aaaaagaagc agatttaata gaatcaaatg atactttaaa aagaaatcta ggtataataa
     8761 aacaaaatgg aaatagaata ttgaggttag taaataatgt tatagacttt acaaaaatgc
     8821 aatcaggata tttagatttt aaaccagaag aatctgatat aattgcattt atagaggaga
     8881 tatgtatgtc tgtagctgat tttgcaagcc aaaataatat acaacttaca tttgatacag
     8941 aaatagaaga attttcaatg ttatttgatt cagaaaaatt ggaaagaata atattaaatt
     9001 tactttctaa tggaattaag tacaataaga aagatggaaa aataaatata tttttatatg
     9061 tgaaagataa tgtatttaat atgaaaatat ctgatagtgg tataggtata ccaaaagaaa
     9121 aaatagataa aatatttaat aggtttgaac agattgacaa tgaactttct tacagagtta
     9181 aaggaagtgg tattggactt tcattagtga aatctttggt tgagttgcat gagggaagta
     9241 tatctttaaa aagtcaactt ggtattggaa gtgaatttat agtttcattg cctgttagaa
     9301 gtaaaaataa tattgaaaaa tataatcata aaagagaaat cagcaatgaa ctaagtaaaa
     9361 aattagaaat agagttctcg gatttataag tttaaatata aaaaataaaa ttttaaaaaa
     9421 gtattgacaa ttgatttaga agggtttaaa ataaattaca acataataaa taaaaaggcg
     9481 atgaatagga agagtaaatc taattcgatt accagagaga agagtccgtt ggctggaaga
     9541 ctttttaaat tagagggatt gaaaactacc taggagctac tttctgaagt catctgcatt
     9601 agtagatttt agtaagaata gtcgttagct gcgttaaagt gtaaagtgag ttttcatgac
     9661 atatgaaaac taaattaggt ggaaccgcgg gaataatact ctcgtcctta tgttataagg
     9721 atgagagttt tttgttattt aaaaatataa acagtaatca taataattat agaaaatata
     9781 aaagcaatga ataggaagag taaatttaat tcgactatca gagaggaaag ttcacaggct
     9841 gaaagacttt ctaagtttga gaaattgaaa actacctagg agctgtggtc tgaagttact
     9901 ttaaaaagtt ttagtaagac taaccgttaa ctgcgttaaa gtgtaaagtg gattttatca
     9961 ataaatgata aaatcaaatt gggtggaacc gcgagtatag actcgtccct ttatataggg
    10021 atgagtctat ttttattgca ataaaagatt gaaaataaaa aaaaatcgga aaattataaa
    10081 tttaggagga aaataaaatg gagaataaag tgaaaattgg agtactagga tatggagttg
    10141 taggaagtgg acttatagat ataatagata ataataaaga aaaaagaaat atagaaatag
    10201 ttggaatttt agttaataat ttggaaaaac ataaggataa aaaatattct aatataataa
    10261 ctaataatat agatgatata tttaataaag atatagatat acttgttgaa gtcatgggtg
    10321 gtttagaacc atcattatct tatataaaaa aagcattaaa caataaaatt catgttgtta
    10381 cagcaaataa agatttgtta gctgaatgtg gagatgagct tgcaaaatta gcaagtgaaa
    10441 ataaagtaag tattaaattt gaagcttcag ttgcaggagg tataccagta ttaaaaccaa
    10501 taatagaatc actagaagga aataatatag atagtataaa tgcaatttta aatggaacta
    10561 ctaattttat attatctaaa atgtatgatg agaatctatc ttatgatatg gcattaagac
    10621 aagctcaaga attaggtttt gctgaagcaa atccagagtc agatgtatta gggtatgatg
    10681 ctgctagaaa actatcaata ttatcaactc tagcttatga caatagagta tattggaagg
    10741 atgtgtattt agaaggaatt acagatatag atgaaaaaga tattgaatat gcaaaaaaat
    10801 taaattgtaa aataaaattg attggtcaaa gtaagtatga aaatgataaa gtaagtgctt
    10861 ttgttagacc tgttttagta gaaaaagata atatccttgc tagaatagac aatgagttca
    10921 atgctgtcat agtgaatgga gattcagtag gagaagtttc ttttgtaggt aaaggcgctg
    10981 gaagtttagc aacaggaagt gcggtttatt cagatgttat agatataata gataatagag
    11041 tttcaagtat agattctttt actaaagata aaatacaagt taataaaata gttagagaaa
    11101 agtgtggagc acttcttaga tttaaaaaat gtaataaaga tgaaattcta aatatagttg
    11161 agaattgttt agtaaaattc gatattttaa atgatgatga tgaacttgct attatggttt
    11221 atgctgattc tgaatatgaa ataaacaaca gtttatgtct aataaaagat aaaggatact
    11281 gcgaaaaaat gaataaaatg ttgaaaataa gttaaaaaag aaaaaatata agtttatatg
    11341 taacatattt tgacgatttt aatactatat agtatgagat gaaacaaaac atctcataaa
    11401 aaaattaaaa ttcaagggag agatatgtta tatggaaaat aaaaaatatg caaatggtgg
    11461 ttattcagaa gactggtatg aaagaggaga atctacagct aaatggttcc agaatgatag
    11521 agaagaatat gaaagagcag catacgatga agatagagaa agaagaggct caaactgtgg
    11581 atgttcagat tcaggagaaa atagacctag aaactgtgaa agatttagaa gagaagcaga
    11641 gataagagaa agagaagcaa gagaagcatt ctgtgaatct tcagagagaa agaaagaagc
    11701 actagcatat gaatgtgaag ctagaaaatt atgggaagaa gcagaaaaat actgggatga
    11761 atattcaaaa tacaactata aaggaatcga atatttagca gaagctgcta gattatttga
    11821 tgaaggtatg gaatgtgaag ctagaagaaa tggaaataat ggaggaaaca ataataattg
    11881 ttgccataaa tgccataaat gtaattgtaa ctgctgtaga aaataaaaaa attaattgac
    11941 aaatcaatag ttaaaatata tcatattatg tataataaag agaaaattca gaaaaaaata
    12001 atgattagaa gaaatataag tatatttatt agacaaatag tgctcagtta gtgaggtgag
    12061 tacaatatga ttaaactccc atcctctagc ttttgataga gggtgggagt ttttatttat
    12121 ttatatatct taaatgagga taatattgta aaataaatga gtatgagatt gtaaaattag
    12181 gaggtaaaaa atgaagagta ttaaaacatc aagtatgaaa gaaaaggtag atgaaaagat
    12241 attaagagag caagtaagtt ctataataga agatataaga aataataagg atgttgcact
    12301 taaaaaatat aatgagaagt ttgatagaaa tacaagagat gaatttagaa ttactaagga
    12361 agaaataaag gaagcttata agcatgtaga tgacgaattt ataaataact taaagattgc
    12421 tgccaaaaat ataagagaat ttgctaaagc tcaaaaacta agttttgaaa acccttttga
    12481 aaaagaaatt tatccaggtg taatcttagg tcaaactaat attccaatag agtcatgtct
    12541 tgcatatgtt ccaggaggtc agtatccatt gttttcaaca gctcttatgc ttataatacc
    12601 tgcaaaagta gcaggagtaa aaagaatagt ggcatgttca ccaactatga aaaatactga
    12661 aaagataaat cctaagacat tggtagctat ggatatagca ggtgctgatg aaatatatgc
    12721 aactggagga gttcaagcta tagcagcatt tacatatgga acagaaaaga ttaatccagt
    12781 tgacataatt gtaggaccag gaaataagtt tgtaactgaa gctaaaagac aatgttatgg
    12841 acaagtaggg attgattttg tcgctgggcc aagtgaagtt cttataatag cggatgaaac
    12901 ttcaaatcca gtttatattg cagctgattt attagcacaa tgtgagcatg atttaaatgc
    12961 aagaggaata ttattgacaa atagcttgga agtagcacaa aaagttgaaa aaaatataga
    13021 aagtatgcta aaagatttgc caacaaagga catagcatat agttcatggg aaaataatgg
    13081 agagataata ttggttgatg atatggaaga agccattaaa ataagtaatt tttatgcacc
    13141 agaacattta gaagttgcag taaatgagta taatgatatt tgtgatagat taactaacta
    13201 tggttcttta tttattggaa atctttctgc tgaggtgttt ggtgactatg tttcaggtac
    13261 caatcataca ttaccaacac ttaaagcatc aagatatact ggtggtgttt gggttggaac
    13321 ttttatcaaa acttgtacaa agcagatatt taatgaaaaa gctatacaat cattagcacc
    13381 tgtagctgaa aagctggcaa aagaagaggg attatatgca catgcaaagg ctgctgaggt
    13441 taggtttaaa aagtagtaaa aaattttatt ttggcagtcg agatttagtg ttagactgag
    13501 ataaggaaaa cgctgagaac ccgaataaat actatatttt gtgggcctcg gcgtttcttt
    13561 tatatctgta tataatagga taatactacc tgtgtgttta aatgctagct taatatttct
    13621 tttctaaata atgtttatga aatagttaat atttttagtt aatacttgaa aaaaactttt
    13681 gctaactgtg caaattcatc tgcattcgtc aatatagcag ggtgtcctcc ctgactaaaa
    13741 atgtgaatac ttgcttttga aataaaagtt gccatttgtt tgtactcttc ttcaagatta
    13801 tgacgacaca tttcgtcttc cttacttcct gtaaataaaa ttggcatttc taatttacac
    13861 aattctttat gaaacaaagg gcgtttctcg tttgcacatt gcaatagagc ttttgtatca
    13921 agattaacaa cattctccca atcttttcca tgacaccatt catagaattt tcgtgcttga
    13981 atatcttgct ttgatttttc ccttccagtg attagattat ctatgaagtt atcattaaga
    14041 gtacgtccat caaagctatc tgctataatt gcttcaacta aatcgggacg ttctaatcca
    14101 gtattaacag ctgcccatgc tcctccactt gttccaatta agccaacttt accacaattc
    14161 aaatgttcaa tcaatgctat tgtctgtaag gcttcatcat gccatatgtc aggagaaaat
    14221 tgagaaactc tatccgactg tccattacct aaaaaatcaa ttaagataca tctaaaattt
    14281 tctacatata atggcacaag tgctttaaac atattagaag aaccagtatt accatgcagg
    14341 aaaattatcg gtttaccttg tccatattct ttataaaaac aagaattacc ttgatactga
    14401 aaatatgaca tatattttcc tcctttttat ttgttaagtt aattataaca atataggtat
    14461 gaatgaaaaa cctcatgttc tttcttagaa taaaaatgtg ccacgcataa aacgtgacac
    14521 atttctaatt ataaattttg ctgtttaagt attctttgta tgcttttctc tgtcaaaaag
    14581 tatttctctg ataactgctt gatactcatt ccattttgga aatttataca gatttgagaa
    14641 ttacgagaag ctaagacttg tttggtgttt gtgttttcac cccaatgctt tttgtgctct
    14701 tgctttttgg gaatataaat cactttacca tctatatatt cttgcacttg ctcaatcagt
    14761 tctttaggca gtaagtcaat cgaattttga tagctcattt tgcacctcct aaataattat
    14821 tctttaggat tagcaaaggc tactgccact cacaattaaa aataaaattt tttattatgt
    14881 acaatagcct ttgctatgca caagttccaa ttcccataaa ctaaatactc ctttctggtt
    14941 tgaaaaattc atctgaacat tgatttcgct tttaagatag agttcaatga caaatttaca
    15001 tttttattat atatattcag atagataatt gcaactgtct ttgtatgagg atattttatt
    15061 atagtcaata ctataatatg tatttatatc atcaaactaa tatgaacagt tgaaaggaat
    15121 atgaacaata aaacttagtc aggaagaata attatgaagc agacaataga gaaatttgat
    15181 tttaaagttt tattgaaaat ttattgacaa atttaacttg taaatattat actaaactta
    15241 ataaataaag tttataaagt aaggtgttgt ctatgaaaaa tatagttgga aaaccgcaaa
    15301 cgataaaaaa agtaaatgaa gatttaataa aaaatattat aaaaaatgaa ggtcctataa
    15361 caaaaccaga aatttcaaac attactgaat tgagtttagc tacagttaat aagattgtag
    15421 agcaattagc tttgaaaaat gaagttaaag taagtggact aagtgaatct actggaggaa
    15481 gaagagctca attatttgaa ataaatgcaa acttagaaca cataatagct ttatattatt
    15541 atagaaattg ttgtataggg gtagttgcca atttattagg tgaaataatt tatcaagaag
    15601 aatttaatat aagaatggat acatatgaaa acgttaacca agatactttt tttgttatag
    15661 atactctaat aaaaaaggaa aaaggaaaca atataagggc tattggaatt ggtgtcccag
    15721 gagttgtaaa aaaaggtgta gttaaaaata taccaactat aaaaagttgg gaaggtataa
    15781 atttagaaaa tttaataaag agtaaataca atactaaagt gtttatagaa aatgatacaa
    15841 atattactac tattgggatt tatcaaaaac agtataaaga caaatataaa aatatggctc
    15901 ttatgtattt agaagatggt attggttcag gtatagttat aaatggtgaa ttgtatttag
    15961 gttctacaaa ttttgctgga gagttaagtt atctaaatat agaatttggt aagtataact
    16021 ctaacaactt aaatcttgaa gattatatta tgagtttaag aaaaagatat ttagaaagta
    16081 aagataataa atttaagaaa gaaattttat ctataatatc aaactttata aggactcttg
    16141 tatgtgtcct aaatccacaa gctatgatta tacagtgtag tatattaacc aagagtgaca
    16201 tggagtttat agaaaaagat gtaagcaata atgttggaga agaaaatttt cctaaattaa
    16261 taaaagtaga gtcattgaga gaaggaagta taaatggagt aattagtatg tgtttaaaag
    16321 aaactgacta tcaatattcc ttatctaata aaaaaggagg atattaatgt gaaatatttg
    16381 gtttcaatag atggaggggg aacaaaaact aaattttgtg taagtgactt agatggaaac
    16441 atacttaaag aacataccac tggttcaact aattataagt cagttggaat taaaaaaaca
    16501 tatgaaaata ttaataatgg atttaaaaaa atattaaaag atttatatat cgattatgac
    16561 gatattgagt acactgtatt tggtatatct ggttgtgatt ctcctaatga ttataagatt
    16621 ataatggatg aaatattaaa aattgggatt aacaaagaaa aaatatatct ggcaaatgat
    16681 gcagttttag ctttttatgc acaagcggat tcccctggtt tagtaattgt ggctgggaca
    16741 ggttcaatta tactgggaat taaagaagat ggagaaatat atagagttgg tggatggggg
    16801 tataatttta gtgatttggg ttctggatat gatataggga gaaaattatt aaagaaagta
    16861 ttgctttatt gtgatgaatg tcatgagtat agtgatttat ttagttgtgt cttggatttc
    16921 tttggagcaa atagttttga acaacttgca tatatgatta ctgatataaa caataatgtt
    16981 gaaatagcaa acttagcttc attagtgatt gattgtgccg aacaaggtga taaattggct
    17041 attgaaatat taagagaatc atcaactgaa ctatctaaat tagctcaagt aatattgaga
    17101 aaaatatcta atccaatgaa agtggataaa agcgaaataa atatagtttt gtctggtggt
    17161 acattaaata aaactgtata tgctcaaatg ttaatgaata atttaaaaac agaaaataca
    17221 gataaaaatt taaaatttat atctcaagaa aatcagccag tgtatggggg gataagactt
    17281 gctatggcat tagctaatag gagggtcaag catggataga aaaaaggtaa tagtacaaat
    17341 ttttactgga ggttttaagg ctaaagaaat aaagtttaat gatataaaat gtaaactact
    17401 agaattattg gactgtattg atatagaaaa ggttatcatg ggatggagtg tagatgaaga
    17461 attatatgta gaaactaaaa aactattaaa taaatataat gttgaactat atctttggtt
    17521 gccatgtttt tctgaaatag gattacttga aaaaagtaat ttgctaattg attatatggg
    17581 gaaggaagtc aagggctatg ctttacaaga ggatgaaaat tttgagtttt attgcccaaa
    17641 taataaggaa aatataaaaa atataaagaa aatatatagt acttatttta gtgatattaa
    17701 atttgatgga atttttttag ataaaataag gtatggttct ttttcgaata aactaaatgg
    17761 tgtttttaat tgtttttgta aagattgttt aaatatatat gaaaaaaata atattgataa
    17821 agagtcgtta atgagagaaa tgaataatgt gtctaaggga gttatagata atgaagatac
    17881 tccatttggt ataacagaat acattaatgg aaaatacaaa tttaaaaata aaatatggga
    17941 agattttttt gaaacaaaaa atcaaaatat atacaaggca ttattagaga taagtaatta
    18001 ttttaaaagt aagggattga aaataggtat agatactttt tctcctttta tttcttactt
    18061 tacaggtcaa gatttagaaa aattacaaga agtagcagat tttataaaac caatgatgta
    18121 tagaactaca aaagctccag ctggtttacc atttgaattt gaaaggttta ttgatgaatc
    18181 catacataag aataaagaga ttggaaaaag aaatttctta gatattttag gaattaagga
    18241 gtatgaagga gatgtatatc ctatagaatt tgtactagag gaaatcgatt ttatgacaag
    18301 aaatcttaat aaagatatat atgtaggagt tgaaataaat aaaaaggaaa ttatatctcc
    18361 tgttacacct aagtacataa gtgaaaatat ttcaaatata aataagacaa cagtaaaagg
    18421 atatgtttta tcttgggatt tgttgtcagc accaaaagaa aatattgatg aaattataaa
    18481 atggtttcgg aattagtgag gtgataaagt gagtaagata ttggaaatgc aacaaatata
    18541 taaaagtttt ggaaaggtag atgttttaaa agggataaat tttgagttag aaaagggaga
    18601 agtaagagct cttttgggag ctaatggagc aggaaaatct acacttatta aaattttagg
    18661 aggagttcat tctcaaacta aaggtaaagt aattttgact ggtaatgaaa taatgtttaa
    18721 aaatccacat cattctaaag aaaatggtat tagtataatt tatcaagaat taagcttgat
    18781 accaacgctt acagtacttg aaaatatttt tcttggtaga gaaattttaa aaggaagtgt
    18841 gtttttaaac aagaaagaca tgcttgagga atgtatgaaa atttgtgagg attttgattt
    18901 taatatagac ccacatatgg tagtttctaa tttaagtgta gcaaaccaac aaatggttga
    18961 gataatgaaa gctgtttcat gtaattctga aattatcata atggatgaac ctacaacatc
    19021 acttactaat aatgaaaaag atgggctatt taaaataata agtagactaa agtctaaagg
    19081 taaaacaata gtctatattt ctcacatatt agaggaagtt tttaaagtat gtgatagtgc
    19141 aagtataatg aaaaatggaa ttatgattgg aacttatgat gtagaggatt taactaaatt
    19201 aaagataact caacttatga caggaaatga taatcacaaa cttattgaga agaaggatta
    19261 tacatttgca aaatatgaag agccaccagt actagaagta aagaatataa gctggtctaa
    19321 caaaataaaa aatgtttcat ttaaagttta tagaggcgaa gttgtaggtc ttgcaggtct
    19381 tgtaggttca agaagaactg aaattataaa tttgatattt ggtatagata ataaagatag
    19441 tggagacatt tttatcaatg gtaaaaaagt agacataact tctcctaagg ttgctataaa
    19501 aaacaaaata ggattgattc ctgaagatag aaaaaatcta ggattaattt tagaacaagc
    19561 tatatacaca aactcatcat cagtacaaat tgataaattc aagaaattct tgtttataga
    19621 tagaaataaa gaaattgagt tttctaaaaa aggtgttaag gaattaggaa taaaagttaa
    19681 tgatgtaaag caagaagtaa aagagcttag tggtggaaat caacaaaaag tagtagtttc
    19741 taagtggtta gagaaagatt tagatttaat aatatatgat gagccgacaa agggaataga
    19801 tattgctgca aaagaagata ttttcaatac aatcaaagaa ttttcaagta aaggaatagg
    19861 agtaatattt atatcttctg atttagaaga agtaataaga gtaagtgata gaattttagt
    19921 aactagagaa ggttctattg tagatgattt aaaaaatgag aatatacagg ttcaagatat
    19981 aatgaacagt atatttaatg tataaaaaat gaaaatggag gactgaaatg aagaaagctt
    20041 ttgagaagtt aaatttaaga gattatggag tattattagg ttttttagct ttatgtatag
    20101 ctataagtat tgcaactcca tcatttttag gtaaacaaaa tatacttaat cttttacgac
    20161 aatcttctat aattggaata atttcagcag gtatgacttt tgttataata tctggaaact
    20221 ttgatatatc agttggagca gtagcagctc ttgcaggtgc tataacaatg aaatttgcga
    20281 ctggtggaac taatttgttt gcatccatgc tcttaggtgt agcgatttgt gcagtaatag
    20341 gattaatcaa tggtatagta gttgcaaaga taaatgtacc atcattaata gccactatgg
    20401 ctatggtcac tattgtaaga ggattgctgt tgatgcttac aggaggatat ccaattactg
    20461 aaaatatacc aatacttgat tacattggaa atggatattt gtttaatata ccaataccag
    20521 tagtaatttt ctttatagtg gtgttagctt catttattgt acttaataaa actaagtttg
    20581 gtagatatgt ttattctgta ggagggaatc aagaagcaag taaacttaat ggtataaatg
    20641 tagattctca caaagtgaaa gtatttatta ttaatgctgt acttgcagga atagctggaa
    20701 tcgtactaac aggaagactt gggactgcaa ctgcgattgc aggtgaagga tatgatatgg
    20761 atgcaattgc atctgtagta ataggaggta catcagtggc aggaggttct ggttctgtac
    20821 ttaaaactgt tataggagta ttacttatga gtgttataaa caacagtttt aatcttcttg
    20881 gaatagatgt atatttccag tacatattta aaggattaat aattttagca gcagttggat
    20941 ttgattctta tagcaagaaa aaacttgctt caagataaaa aataaggggg atttttttat
    21001 gaaaaaatta atgaaacatt tagcattgtt gctatcactt gttatgatat ttggtttagt
    21061 tggttgttca aatggtggtg acaaagaaaa aaatggagaa aagaaaatag cagtattact
    21121 accaggttca acaggttact ttgtagcaac taaacaaggt atagatgcaa aatctaaaga
    21181 attaggtgta agcgtggaat atgcagatgc tcaatgggat gctagtaaac aattatcaca
    21241 agctgaagat tttatggcta aaggggtaga catgattgca ttatgtggag ttgattctgc
    21301 tgtaagtgag agaatagtta aagctgctaa tgattcagac gttcctatag tagcatttac
    21361 aaattctata ggaagtaacc caactggaga atttaaaggt ttagttacat atataggaca
    21421 aaatgaggaa gaaacaggag cattaactgg aaaaattgct aaaaacttat taggagaaac
    21481 tggtgggaaa gctgtattaa tagaaggagt accaggaact actccacaag tattaagaaa
    21541 aaaaggtctt gaaaaagaat taaaagatag taatatagaa atagtttata atcaaacttc
    21601 aaattgggag aaagagcaag ctttaaaggt aacagaagat ttaattcaaa agaaaactga
    21661 ttttaatgtt ataatatgtc aagatgataa ttctgctaca ggtgcaggtc aagctttaaa
    21721 agatgctggt cttaaggata aagttaaagt cataggtttg ggtggaagta aagatggatt
    21781 aaaagctata actgatgggt taatagatgg tacaacttat atgtctgctg tagaagaagg
    21841 tggattagtc atagaaaagg catctaaatt ccttaaaggt gaaaaaatag aacctgttac
    21901 acaaattaaa caagttgaag ttaacaaaga taatatttca gagttcaagg gtgaatggta
    21961 aattgtcata gataataaat aagattttta gagttacttt agaaactata taaagtaact
    22021 ctttttttaa tttaatttag tgataaatta ttgaatagta tttctaaaca aataaaaaat
    22081 taatataaac aaagacttaa ttatactaaa ttataagtaa aactaatata aacttatgga
    22141 aaaaaggaaa acgtctaaag tattggaatt actatagtgt aggtgtggta ttaaaaaaac
    22201 ataaaaaaac ataaaaaaat tgttgaaaaa aatatagaaa ttttgtataa ttaaagattt
    22261 gaaaagtgcg gtatacaaag ccaattcttt tgtatataat atatataaat tcagaaaaag
    22321 gaagggatat gtatggccag gcggttattt ttagaaagga ttggacttat atttttaggt
    22381 tcagcaatat tagcatttgg agtttataat ttttattatt taaacaacat aacagaaggt
    22441 ggagtgttag gtattttact actgttaaaa aatttattca atatacaacc agcaatagca
    22501 aatgttgtaa tagatggttt gctactttta gtaggatata aatttttcgg taaaaaattc
    22561 cttatatatt caatagtagc ttctataact ttttcagtgt tatatgactt atttgaagct
    22621 ataggacctc tagtaccaca atcacaaaat atgcttttat caactatttt ggcaggtgta
    22681 actgttggaa ctggtgtagg tatagtagta aaagcaggtt gtgcatcagg aggagacgat
    22741 gctttagcat tagtaatttc taagactaca tctttgaaca tagggcaagt ttatttagca
    22801 acagatgtta ttgtattgtt gttatcatta ttttatctat cagcgtttga tatcttttat
    22861 tctttgattg ctgttacaat tagtggcaag gtaattgatt ttatttatta tcatggtaaa
    22921 agtttggata tggatataag taatgatata gttccagaat gttaatataa attaaataac
    22981 tttagatttt attaggggtg gcagatttgc cacctttttt gtgtctaaat ctttatagaa
    23041 agtataatcc tatctaggtt tttgcaaatc tcaaatatag aattatgttg aaatgactgg
    23101 gaatacgatt gctagatgtg cattttaaaa acccaatttt atatttatga aatactaatc
    23161 attaatggat gtttcttaat cctatcttta tacctaaaat gataagataa atgaagtagc
    23221 aatacaaaac taaaatttgt aaaagagatt aaattaaatg gaggagctaa aatgttggat
    23281 atagttatga tagcattgtt attcatagga tttgtttcca tgaagttact tgctgattgg
    23341 tgtgggaaac aaactgaaaa aaaataatgt aatgtatgga gggattacct atgtggtttc
    23401 tggcagttgt aattataatg ttaataatat atttggtata tgcgcttatt aatcctgaaa
    23461 aattttaaac agtataaggc taataagtaa gttgaattgg ggggaacaat ttttatggtg
    23521 cagatagtaa tagtgttagc gatttttatg attttagtaa tacctatggg caagtattta
    23581 tatcatatag ctactaatca aaaaacattt ggagatagac tatttgataa agtggacaat
    23641 tttatatata aggtatgtag tatagataag aaaaaagaaa tgaactggaa acagtatgca
    23701 ttagctttat tatttacaaa tgcagttatg gtatttatag gatatatcat acttagaact
    23761 caaagtatgc atatttttaa tccaagtgga attaaaagta tggaacaagg actatcattt
    23821 aatacaataa taagttttat gacaaataca aatcttcaac attattcagg tgaatcagga
    23881 ctttcatact ttagtcagat gacagtgata atatatatga tgtttacatc agctgcaaca
    23941 ggatatgcgg ctgctatggc atttgtaaga ggtctagtcg gtaaaaagaa aacattggga
    24001 aatttttatg tagatttaat taggataaca acaagagtac ttttaccagg agctttaatt
    24061 attgggctta tattagttac acaaggagta ccacaaactt ttgctgggac agaaacagtg
    24121 actactatag aaggaaagct tcaagatata gctagaggtc ctgtggcagc tcttgaatca
    24181 ataaaacatt taggaacaaa tggtggtgga ttctttggtt caaattcatc acacccattt
    24241 gaaaatccaa caataatatc aaatatagta gaaatattat ctatgatgat attaccagga
    24301 gcttgtgttg ttgcatttgg tcacatgata aagaataaaa aacaaggttg ggttgtgttt
    24361 ggcgcaatgt caatcatatt tttaataggt ctagtagtgt gctttaaagc agaaagtgca
    24421 ggaaatccta ttttatcaca attagggctt aatcaaagta tgggaagtat ggaaggtaag
    24481 gaagttagat ttggtatagc acaatcatca ttattcacaa cagtgactac ttcctttacg
    24541 acaggtacag ttaataatat gcatgataca ctgactcctt taggaggatt agtaccactt
    24601 ttaaatatga tgctaaatgt agtatttggt ggtaaaggcg taggtctgat gaatatgttg
    24661 atgtacgcta taatagcagt attcttatgt ggattaatgg taggaagaac accagagttt
    24721 ttaactaaga aaatcgaagg aaaagaaatg aagcttattg ctttacttat tatattacat
    24781 ccacttttaa tactaatgtt ctctggtctt tcagtagcaa taccagcagg acttgaagga
    24841 atttcaaatc ctggattcca tggattatca caggtattgt atgagtttgc atcttcagca
    24901 gccaataatg gttcaggatt tgaaggtcta ggagataaca ctatgttttg gaatataaca
    24961 acaggtatag ttatgttctt tggaagatat gtgtctatta tagtactact agcaatatca
    25021 agtttgttag catctaaaaa agctgtaaat gaaagtatag gaacacttag aacggataat
    25081 tttacattta caatagtttt agtacttgtt gttttaattg ttggtgcttt aacatttttc
    25141 ccagccttag cgcttggacc tatttcggag catctagtgt tgtggcacta aaaaattggg
    25201 agggagtaaa gttttatgga aactaaaaaa acaaagttta ttacaaaaga tattttcaaa
    25261 acttccatta tagaagcttt taaaaaatta aatcctaaat atatgatgaa aaatccagtt
    25321 atgtttgttg tagaaattgg atttatagta acattgatac ttacaatagt acctagtttg
    25381 tttggtgatg aaggcaataa cttaagagct tataatggga ttgtaacaat aatcttattt
    25441 ataacagtcc tttttgcaaa ttttgctgaa gctgtagctg aaggaagagg taaagctcaa
    25501 gcagatacac ttaagaaaac tagaaaagat acagtagcaa gggttataga tacgttagga
    25561 aatgaaaaaa tgataagtgc aagtgagcta aaacttggtg atattgtttt agtaaatgct
    25621 ggagaagtta tcccaaatga tggagaagtt atagagggta tagcttctgt ggatgagtca
    25681 gcaataactg gagaatctgc acctgtcatg agagaatcag gtggagattt cgcatctgtt
    25741 acaggtggta ctacagttgt aagtgactgg ttaaagataa gaataacaac aaaaccagga
    25801 gaatcgttct tagataaaat gatagctctt gtagaaggtg cttcaagaca aaaaacgcca
    25861 aatgagattg ctttaaatac tttgttagta gggttaacac ttatatttat ggttgtttta
    25921 atatctcttt atccaatggc aaactatgca ggtgtaaaga ttccaatttc tactatgata
    25981 gctctcttgg tatgtttaat accaactact ataggtggat tgttgtcagc tattggtatt
    26041 gcaggtatgg atagagtaac tagatttaat gtaattgcaa tgtcaggaaa agcagtagaa
    26101 gcttgtggag acgttgatac tatgattttg gataagacag gtacgattac ttatgggaat
    26161 agacttgcat cagaatttat agcagttgga aatgcagatt caaaagattt aataaattat
    26221 tctgttatgt gttcattaaa agatgataca ccagaaggaa aatctatagt tgatttaggt
    26281 atgaaattag gttcaacagg taagacaaaa gaggcagagg aagctgagtt tgtagaattt
    26341 tctgcacaaa ctagaatgag tggtattaac ttagctgatg gtagagctat aagaaaaggt
    26401 gcttatgata gcataataaa aagagtaaaa gaatctggtg gtacagtgcc agaagattta
    26461 gaagaaaatg taaatcgagt agctaaacta ggagggacac ctttagtagt gtgtgtagat
    26521 aatgagatat atggaattat ctacttaaaa gatacagtaa aatcagggct tgtagaaaga
    26581 tttgctagac ttcgagagat aggaataaag acaataatgt gtacagggga taatcccttg
    26641 acagcagcta caattgcaag agaagctgga gtagatggat ttattgcaga atgtaaacca
    26701 gaagataaaa tagatgcaat aaaaaaagaa caattagagg gtaaaatagt tgcaatgaca
    26761 ggtgatggaa caaatgatgc tcctgcactt gctcaggcag atgtaggtct tgcaatgaat
    26821 agtggtacaa catctgcaaa agaagcagca aatatggtgg atttagattc agacccaact
    26881 aagatattgg aagttgttga aataggaaaa cagcttttaa taactcgtgg ggctttgaca
    26941 acatttagta tagcaaatga tgttgcaaaa tattttgcga ttataccagc tatatttact
    27001 cttgcaatac ctcaaatgga gatattaaat gtaatgaaac tttctacgtc atttagtgcg
    27061 atattatcag ctttaatatt taatgctata attatcccat gtttaatacc tcttgcaatg
    27121 aagggagtaa aatatagacc tatgaaatca caagctatgt taatgagaaa tatgcttata
    27181 tttggtcttg gtggagttat agtaccattt ttaggaataa aattaattga tttattgatt
    27241 acacctttag taatggttct taatttaggt taataaatgg aggatataaa aatgaaaaca
    27301 ttaaagccag cattacttgt aagtattgta ttgttagttg tttgtggact tgtatatcca
    27361 cttgttttga caggtgtaag ccaagttgca tttaaagata aagctaatgg aagtatgata
    27421 gaagtaaatg gtgtaaaagt aggttcagaa cttattggtc aaagctttac agatgcgaga
    27481 ttctttaagg gaagagtatc atcagtaaac tataatactt atacaaaaga agatttagta
    27541 ccagataaag atggaaacac atcttatgga ggtgtatcat cagggtcttt taattatgga
    27601 gctacaaatc cagaacttca tgatagagta caaaaagata tagaacagtt tttaaaggat
    27661 aatccaactg tcaaaagaga ggatatacca acagatttac ttacagcatc aggttcagga
    27721 cttgacccta atataagtcc agcctctgca aaaattcaga taccagctat agcaaaagcg
    27781 tctggaatat cagaaagtaa attacaaaaa attgtagaag ataatacttc caaaaaactt
    27841 tttggagttt taggtgaaga tagagttaat gtattaaagg ttaatgtaga ggtcgcaaaa
    27901 atattaggtc ttatatagta ttttgtggaa ttttagcaac aaaatattac tcaagattta
    27961 atttaaaggt taaattttaa agagtgaaaa tcgataatga ttttcacttt tttatttgaa
    28021 tattactaat atttggaata aagtgattgt aagtataaaa tccaaaaaaa ggttgcatta
    28081 tcaaaatgat aatactataa tatatttatc gttatcaatt tgataataga tttggacata
    28141 taggaggaaa tagtatgtta tataataacg cattagagtt gataggaaac acacctgtag
    28201 taaggctgaa taatttaggc tgtactaatg ggtgttctaa catatatgta aaattagaaa
    28261 aagtaaatcc agcaggaagt ataaaagata gagctgttta tgaaatgtta gagggtttag
    28321 agcaaagagg agaattaaaa aagggagatg tactagttga agcaactagt ggaaatactg
    28381 gtattgcatt atctatgata ggaaaattaa aaggatatga agtagtaatc gtaatgcccg
    28441 aaacaatgag cgttgagaga agagatttaa tgaaggctta tggagcaaat ttggtgctta
    28501 cagatggtaa agctggaatg gcaggttcca tagaaaaagc aaatgaactt ttaaaagaaa
    28561 atccaaacta taaaagctta aaacaatttg aaaataaaga taatccaaat gcacattata
    28621 aaacaacagc agttgaaatt atgaatgatg tcaaagattt agatatattc gtatgtggag
    28681 ttggaacagg tggtacttta ataggaactg caagatattt aaaagaacaa aatccaaata
    28741 taagagtaat tgcacttgaa ccaaaaaaat ctccagctat atcagaaaac aagactggac
    28801 ctcataaaat acaaggaata ggtgctaact ttgttcctga aaattatgat tctagtgtag
    28861 ttgatgaagt aatattagta gatgatgaag atgcatttga tacagttaaa ttacttgcag
    28921 caaaagaggg aattttagta gggatatctt ctggagcaaa tatatttggt gctatagaga
    28981 tggcaaaaaa gtatccagat aaaaagatag ttacagtagc tccagatgga gttgataagt
    29041 atatgtctat gggaatattt taataatttt atttgaggga gtgaatactt tgtttaagaa
    29101 aataaataaa gatattgaat atataatgaa gaatgatcca gcagctaggt ctaagataga
    29161 agttttttta ctttatccat cagttcatgc aatgataatg cataggatgg ctcatgctct
    29221 ttataagaag aagaagcttt ttacagcaag attaatatcc cagatatcca gatttatgac
    29281 tggcatagaa atacatcctg gtgctaaaat gggggaaggt atattgatag accatggaat
    29341 gggtgttgta attggagaga cagctgaagt aggtaatagg gtgacaatat atcaaggagc
    29401 tactttagga gctacaggaa aagatactgg aaagagacat ccaactgttg gtgatgatgt
    29461 attaattggt gctggaacaa aaatactagg acctttaaat ataggttcaa attcaaaaat
    29521 tggtgcaaat tctgttgtcg ttaaggatgt acctaatggt gcaacagttg ttggtatacc
    29581 agcaaaaata gtaaaaataa gaaacctaga acctgtaaaa aagaataaaa aagaagtgtc
    29641 ctatgagtat gatgaattag ataatgtata ttatatatag gatttatata actataaaat
    29701 aaactttata aaaattattt taaaaggtat ttttttcaaa tttgaggaca taataaaaaa
    29761 gaactgaatg ttacagtttt ggttcatcaa tctttgataa acaagatttt aaatttgtag
    29821 cgtctaggag gattttatta tgaaagcaaa tgttaatcaa gatacttgta taggttgtgg
    29881 attatgtcca tcaatatgtc cagaagtatt tgatatgaag gatgatggga aatcacatgt
    29941 tatagttgat gaagtaccaa gtgatgctga agaatcagca gcagaagcta gagaaagctg
    30001 tccagttgat gcaatagatg tgcattaata aaataaatgc ctataaaaat tgaattttca
    30061 atttttatag gcatttgtct tttattcagt tagtatttca acacctgttt ctgtaactaa
    30121 aaccatacat tcccattgag cagataattt accatctttt gtataaatag tccaattatt
    30181 ttcttcatca acaaaaattt cgtgagttcc ttcatttacc ataggttcta ttgtgaatat
    30241 catcccagga accaatagca tctcagtccc ttttttagat acataactta caaaagggtc
    30301 ttcatgaaag cttaatccaa ctccatgacc acctatttct ctaacaacag agtatccatt
    30361 tttctttgca taagagttga taacatcacc tatatctcct aagaatcccc atggtttggc
    30421 aacttcaaga cctttttgga cacattcctt tgtaacttga actaattttt ttgcattttc
    30481 gttaacatta cctatcataa acattcttga agcatctgaa tagtatccgt taaaaatagt
    30541 agaaacatct acatttataa tatctccatc ttttaagata atgtctttac ttggaatacc
    30601 atgacaaact tcattattta ctgatgtaca tacactttta ggaaatccat tatagtctag
    30661 tggagcaggg atagctccat tttgtagtgt aaagtcatga accaacttat ttatatcttc
    30721 tgtagacatt ccaatttcga ttttatctga aatataatcc aaaatttttg tgtttattac
    30781 agcacttttt tttatttcct caatttgact ttcatttttt ataatatcat gagttggtac
    30841 aatatgacct aacttagcaa atgaatctat tttattatcc atatccatat gacatttttt
    30901 atatttttta gtacttccac accaacagct atcatttcta tttaacttca taacttttca
    30961 tccttctttt attatttatt taaattatgg gttacataaa ctattttaaa acataaccat
    31021 tataaatatt ataacataaa tactaagaaa tcctttatag atagtgattt attcaaagta
    31081 taaattatta tatggttatt gttgatgaaa agaggatagt taaatgtatt attggatatt
    31141 agcgcactta atagtttagt tcaagttttt caagaaaatc atatgttaga ggacaatttt
    31201 cctttaaagt attttttgaa tcttcatcaa gataataatg tacaaatgat tctgcaaaaa
    31261 attcttctat aaacttgctt atatatgcat gtgcaacttg cttagggtca taaagcttat
    31321 atctttcctg agcaaatact tccataaatt cttcagaatt tgatttttta tttaaaacat
    31381 ttttatctat agcatgtgca gtttcatgta attctaaatt ttttgatgaa tgtacatttg
    31441 catagctagg gttactataa cctattttag ccactataga attatttcta tatataccag
    31501 gtacatcttt ccaagtcttg cctgatctta cccaacatgg aggtaattga tattttaaat
    31561 cactaaattc tggttcatca gttagatttg aatttattaa ttttattttt atatcctttt
    31621 ctttaagtgt ctgtaaatat ttaatattta tttttgcaag tctgtttttc atattttcaa
    31681 cttcatcttt atcataattc aagtcatcag gaagtataag catttgttca attatatcta
    31741 tactactgtc ttttatattt tcagattctt catcaaattt atattgaaga gtattatttt
    31801 catagatagt tatatttgta ttattttcta tagaataaga gtgaatatcc tctaaatcta
    31861 aaatattcat ttgttgtaaa atatgttttg tttcgccact ccacactact aaagaaagtg
    31921 aattaaaatt aattagtgga ttttcttttg cttttatatc attgcttata tctacatcaa
    31981 atacatattc aattgagtct tctatgttaa gactatctgt attcttttta atatataaat
    32041 acgcttgttt taagtctata taaatctcat ctaaagattc gtcataaaat tctgataaat
    32101 tattagtaaa gagttcttca cttaaaagtt catttttatc agttatactt tcaattaaaa
    32161 tattaatttc ttttatcata ttgtaaatac ttatttttct atttgctttt tcactagata
    32221 cattgcatgg cgcaagagca atgcaataaa aatctttttc ttttttataa aaggctttaa
    32281 gtgattttga taaaagtgta aagtctacac ctatctgtaa gttgacctta agtgagtcat
    32341 tttgtaataa ttcagtatta tttcttttag ctgtatttaa attgttttcc ataatcattg
    32401 cccccttttt attagggtat cataattttt ttatatgtgt caatttgttt ttttgaaaat
    32461 tataattttt ttgaaaattt tattttttat aatttgtgaa ttttttatta tagaaataaa
    32521 tatgttatta ttatgtcaaa atttagcatt agattcatg
//
LOCUS       DAEPKC010000037        31704 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.037, whole genome shotgun sequence.
ACCESSION   DAEPKC010000037 DAEPKC010000000
VERSION     DAEPKC010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 31704)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31704)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31704
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.037"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..673
                     /locus_tag="KR294_001791"
     CDS             <1..673
                     /locus_tag="KR294_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF1648 domain-containing protein"
                     /protein_id="HBH0239871.1"
                     /translation="KKFKIIYLIPILFTLGMSIFIAFNYNQLPDSIATHWNINGSPDV
                     FIDKSFLNVFKLIGTDFCLMVLLYITSIGSIKSRIKIDTNRIEESRVENIKYLNKIGY
                     LFLILMIIMTTQFFTTLLSIKTKLSTAMNITTLLVIIYLIATYINSPNLKFNSSYSPE
                     EDEKYWIAGIMYNNPNDPSLMVNKRFGIGWTINFGNPLGKILYIAIALLLIFSLFSLI
                     KSLLL"
     gene            793..1269
                     /locus_tag="KR294_001792"
     CDS             793..1269
                     /locus_tag="KR294_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBH0239872.1"
                     /translation="MLSKAEIKYFNECASEILSSEKVQLMRTFPHHGNVSCLEHSLSV
                     AYYSYLLCKKLHLSVDIQSVIRGALLHDFFLYDWHYKGDRKGLHGFTHPREALKNATL
                     FFQINEKETDIILKHMWPLTVKPPRYKEAFIVCLLDKFCCLVETLKIHSLLSPYHV"
     gene            1655..2122
                     /locus_tag="KR294_001793"
     CDS             1655..2122
                     /locus_tag="KR294_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HBH0239873.1"
                     /translation="MFKEMRLKKREMTKEDTVEVLKNGEFGTFSTISENGYPYGVAVN
                     YVYFNDSIYFHCARNGHKLDNISKNNKVSFLVVANESVIPDKFSTTYSSAIVFGKACT
                     VENEEKKNALVEIIKKYSKGFFEEGMKYIEKDMNLTTVVKIEIDHISGKASRL"
     gene            complement(2182..2754)
                     /locus_tag="KR294_001794"
     CDS             complement(2182..2754)
                     /locus_tag="KR294_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HBH0239874.1"
                     /translation="MKVAVIFHSVCGSTYLLAREYKEALEEMNIEVDIFRVSDEVAKT
                     LPQYYLINSKEYKDEFESINVIKSGKEILDYDAIFMGSPTYYGNVSGPMKMFMDSFSD
                     IWVGTPLSGKIFGCFATAGSQHGGGELALQAMNIFAQHMGMTLLSVPCSVRGGYPAYG
                     ILHIAGDNSDIRPNDDAKIGIRDYLKRLNI"
     gene            complement(2817..3914)
                     /locus_tag="KR294_001795"
     CDS             complement(2817..3914)
                     /locus_tag="KR294_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HBH0239875.1"
                     /translation="MLLKSLTRKIEKKYPLNLAEDWDNVGLIVGDFDMDVKKVLVSLE
                     ANEDVIDEAISKNIDLIVTHHPFIFGKINKINSGDLKGRLIQKLIKNDISLYSMHTNF
                     DIAFDGLNDYFMEIMEFGNSKVLDITKSENLYKLAVYVPHNYSDELRKVLSNSGAGHI
                     GNYSDCTFSIEGEGQFKPLEGSNPFLGSVNDIETVNEVKIETVVPQKLLGGVISSMLD
                     AHPYEEVAYDLYKLENKGEIFGLGRISKLDKSMTLESLSRKIKEKLNMKHIRVVGNLS
                     TDITKVAVVTGAGSEFVKKAKRQGAEVLITGDVKYHEAQDALDIGMCIVDCGHFDTED
                     IFKNVMKRFLDEFSEIEVIKSNVYLNPFSTI"
     gene            complement(3928..4617)
                     /locus_tag="KR294_001796"
     CDS             complement(3928..4617)
                     /locus_tag="KR294_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HBH0239876.1"
                     /translation="MKLTDRLLKIASLVSDGKKIADIGTDHGYIPVYLLKEGKVPFAV
                     LADVNKGPLDNAHKEVIQNNLLDKVDLRLGSGIEILEIGEVEEVIIAGMGGILISELL
                     EAKKEVAHNVEKLILQPMQAQEELRYYLLNNGYEILEEVLVREDFRIYEIIVAKYTGK
                     NTIIEDEIYYEVGIKLLENKDSLFNDFIEKKIKTYSSIVNKLEGKNGEAIDKKRKESE
                     VAIKKLENLIK"
     gene            complement(4782..5948)
                     /gene="rpoD"
                     /locus_tag="KR294_001797"
     CDS             complement(4782..5948)
                     /gene="rpoD"
                     /locus_tag="KR294_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HBH0239877.1"
                     /translation="MENKSNKKELKKVTAKTLIEKGKKQGSLTLAEIMEAFSETELDK
                     DQVENLYETLGNLGIEITETKNYKADIDFSVADDDLSIGHLDEDAEAISHDDSSAIEI
                     ETVDLSLPKGISIDDPVRMYLKEIGKIPLLKPHEEVEFARRMHEGDEIAKQRLVEANL
                     RLVVSIAKRYVGRGMLFLDLIQEGNLGLIKAVEKFDYTKGYKFSTYATWWIRQAITRA
                     IADQARTIRIPVHMVETINKLIRVSRQLLQELGRDPKPEEIAKEMEMTEDKVREIMKI
                     AQDPVSLETPIGEEEDSHLGDFIPDDDAPAPAEAAAYSLLKEQIEDVLGSLNDREQKV
                     LKLRFGLEDGRARTLEEVGKEFDVTRERIRQIEAKALRKLRHPSRSKKLRDYLD"
     gene            complement(5966..7756)
                     /locus_tag="KR294_001798"
     CDS             complement(5966..7756)
                     /locus_tag="KR294_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HBH0239878.1"
                     /translation="MNDIKDIIEEIKARCDIASIISEYMNIKQSGANYKGLCPFHGEK
                     TPSFYINTSKQIYKCFGCGEGGDVINFVMKMENLDFMDAVKILANKCGIEINTNMNEE
                     TRIKIEKSKKFQDIHTEAARFYLSNLLGSKNLGYEYLRIRGLDDKIIKKFGLGFSLDS
                     WNSLMNTLISKGYKKQDLLECGLIAKNRDGTNCYDKFRNRVMFPIFDYRGNIIGFGGR
                     VLDDSLPKYLNSPDTLIFNKKQNLYGLNFARKNLESKTIVLVEGYMDLISLYQYGIKN
                     VVATLGTALTEQQGILIKRYADTAIISYDSDEAGIKATLRAIDILTKLGINVKVLDLK
                     DAKDPDEFVRKYGLSDYKKAMDVSTHYIKYKIDHLKKEFNIQKDEERVKFAKEASKII
                     KQLTSPVEIDFYTKYLSNQIDINVESIKREVYGKNYNKPYNNKNQKKIEEKVIEKVEV
                     RQDGKQLVEETLIKIMLEDKKIREIALLKVEESDFLLKESKEILNYMIKNQELDKITI
                     DKLKSLNISEEYLKELNSISLNSINLENTKEIEGIITNIRKNSLEEQINSLLREQQEL
                     ENNNDMKEVDGRVMEIALKIVEINKILKSL"
     gene            complement(8011..8796)
                     /gene="aroF"
                     /locus_tag="KR294_001799"
     CDS             complement(8011..8796)
                     /gene="aroF"
                     /locus_tag="KR294_001799"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HBH0239879.1"
                     /translation="MKENLFNNNSKIEINTNNKKITVKKDKLIIAGPCAIESYEQLLE
                     TAKFVKSQGANILRGGAYKPRTSPNSFQGLKKEGLEILKAVKDEVGMAVITELMDVRD
                     MDELYSISDIIQIGSRNMQNFTLLSEVGKQNKPVMLKRGIASTITEWIGASEYIAIEG
                     NSNIIMCERGIRTYNDYTRNTLDLAAVPIIQKETGLPVVVDPSHATGVRYLVKPMSLA
                     SFACGADGIMVEVHPDPENALSDGAQSLCFNEFEDLMKSINNY"
     gene            complement(8777..9283)
                     /gene="folK"
                     /locus_tag="KR294_001800"
     CDS             complement(8777..9283)
                     /gene="folK"
                     /locus_tag="KR294_001800"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HBH0239880.1"
                     /translation="MNKAYLGIGTNMGDRFDNLSRACELLKNSDSIYKVKESSLYETK
                     PWGYTEQADFLNMCVEIETEFEPYELLEYCQEIERELHRERIVHWGPRTIDVDVLFFN
                     DVVSTDERLTIPHPRIQDRAFVLIPLMDLNEELIINEKTIKEHLNLLSAEEREEVKEL
                     VGYERKPI"
     gene            complement(9276..9641)
                     /gene="folB"
                     /locus_tag="KR294_001801"
     CDS             complement(9276..9641)
                     /gene="folB"
                     /locus_tag="KR294_001801"
                     /EC_number="4.1.2.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin aldolase"
                     /protein_id="HBH0239881.1"
                     /translation="MDKILLSNLGFYGYHGVLKEENFLGQKFFVDMELYIDSREAGLS
                     DDINKSVSYAEVYNVVKDITENKQFNLLEALAENIAEEVLNKFILINGVMVRVRKPEA
                     PVNGIYDYFGVEIRRTRDE"
     gene            complement(9652..10443)
                     /gene="folP"
                     /locus_tag="KR294_001802"
     CDS             complement(9652..10443)
                     /gene="folP"
                     /locus_tag="KR294_001802"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HBH0239882.1"
                     /translation="MFDYGKRTYIMGILNVTPDSFSDGGDFNNLDIAIQHAKDMVDQG
                     ADIIDLGGESTRPGHSYVDSDEELRRVIPVIKKLKQELDIPISIDTYKADVAEEALKL
                     GVTMVNDVWGLRKDKNMASVIGKYDAEVCIMHNQDGTNYDKDIMESIKDFFKVSIEMA
                     MSCGVKKEKIVLDPGVGFGKDFEQNIEVLRRLNELKDLGYPILLGTSRKSVIGKVLPV
                     EPKKRLEGTIATTVLGIRDGVDIVRVHDVYENLMAARMTDAIYRK"
     gene            complement(10507..11079)
                     /gene="folE"
                     /locus_tag="KR294_001803"
     CDS             complement(10507..11079)
                     /gene="folE"
                     /locus_tag="KR294_001803"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HBH0239883.1"
                     /translation="MNKVDKEKIQHAVREILEAIGEDPDREGLIETPNRVARMYEEIF
                     SGLSEEPRDHLKVLFADEKHEELVLVKDIPFYSCCEHHLVPFFGKAHIAYLPKGGRLT
                     GLSKLARVIDTLAKRPQLQERITKNAADIIMEELQPYGVLVVVEAEHMCMTMRGVKKP
                     GSKTVTSAVRGIFEKDIASRAEAMSLITMK"
     gene            complement(11105..11806)
                     /locus_tag="KR294_001804"
     CDS             complement(11105..11806)
                     /locus_tag="KR294_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239884.1"
                     /translation="MIGCIYEVYNEEMTKIIENQNTLAVYLVGSSKDVDFTLYDVVIN
                     DIDVFVFVKEGEKQERILFKKKGIEFDVNYFSKDGVKKLLSNREYFFVKEMKDAKVLF
                     DRENISHIIKDISRDIYLEGPSKMSLEEKSFIKQDIGAKILNLKNKEKFDVFEYHFLT
                     NLYLKDIIIGYFNINDKWVPKDKKLLKVLKKENNELFELVSKVSENYDYQRLLDVYNY
                     IFKEIETKEVIKLIF"
     gene            complement(11840..12583)
                     /locus_tag="KR294_001805"
     CDS             complement(11840..12583)
                     /locus_tag="KR294_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class IV"
                     /protein_id="HBH0239885.1"
                     /translation="MKNNVGFDSSLSKFGIGLFETIRVKNGIAVDLDIHIERMLSSIN
                     CLDLDINYKKDFLINEIVTYIKKENVINKALRITVFDEGYNISIRDIPYNQETYEKGF
                     KLAISPIVRGNSLIHRHKTTNYFENIYTKNIANKTGYNDGIFLNSEGVILECSMSNIF
                     FIKGERVYTPSDRLPILNGIIKKRIIEICDELHIELIENEINISEISSFDFVFVTNSL
                     MGAIKVTEIDKIKFNKENVVFDKIVKLLE"
     gene            complement(12573..13922)
                     /gene="pabB"
                     /locus_tag="KR294_001806"
     CDS             complement(12573..13922)
                     /gene="pabB"
                     /locus_tag="KR294_001806"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HBH0239886.1"
                     /translation="MIREINTKLNSFEIFTIFRNEHDSFILDSAMDKEKLGRYSFISS
                     QPFKVLKYKDTDENPLEVLKEELHKYRVVNDTNLPFVGGAVGYLSYDLGNYIENLPRT
                     AVDDIEMPDMYFGFYNHVIVIDHLVQKTYIATPNIDIELEEKIIDDIEQRILKEEKKG
                     IDSICYEEKEVTPIRLKSNFTKEEFKNAVQSVREYIRQGDIYQANLTQRFSGETELTS
                     FELYRDLRRFSPAPFGAFLNFEDAHILSNSPERFIRCVNKRIETRPIKGTRPRGKDKE
                     EDLRLQQELRNSEKDRAELLMIVDLERNDIGRISKTGSVKVPELFVIEPYANVNHLVS
                     TVVGELKDDKDATDVIKATFPGGSITGAPKIRAMEIIDELEPTQRNVYTGSIGYIGFN
                     GDMDFNIAIRTIIKNDKKVYFQVGGGMTWDSDPDEEYQETLDKAKSIMKALRGYYEE"
     gene            complement(13924..14508)
                     /locus_tag="KR294_001807"
     CDS             complement(13924..14508)
                     /locus_tag="KR294_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HBH0239887.1"
                     /translation="MILMIDNYDSFVYNLVQYIEELGEAVVVKRNNEIKISDIEELNP
                     EVIVLSPGPCSPKEAGICIDIVEHFKGKKPILGICLGHQTIGHVFGGDIIKAQQPVHG
                     KVYSINHTNKGVFRGLKNPLNVTRYHSLIVDSNTVPKELEITAITDKGEIMGIRHKKY
                     LIEGVQFHPEAILSEYGHEMLKNFITEARERVHM"
     gene            complement(14532..15251)
                     /locus_tag="KR294_001808"
     CDS             complement(14532..15251)
                     /locus_tag="KR294_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBH0239888.1"
                     /translation="MTSWKKKTVYKCLIAVALFCGIVLISNFSKVSALMMDTNGNVLI
                     KHGSREKKLIAITFDDGPHPKETSQVLDVLKKYNVKATFFIAGKHAKWYKEPLVRASK
                     EGHEIGNHTFNHPDISNLSSSQIEEEIVKCEDILKEVTGKKPTLFRPPFGSYREKDLI
                     EIAKKHDYKVVLWTGVDVKDWKNPGANSIADKIINKVQNGDIILLHDYATNDTVEALD
                     MFIPKMIEKGFKFVTVSELIK"
     gene            complement(15279..16343)
                     /locus_tag="KR294_001809"
     CDS             complement(15279..16343)
                     /locus_tag="KR294_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HBH0239889.1"
                     /translation="MKRLIALVLVVLIVLFYSPELLKEGYDLKEKFFQSEIWNEFLDK
                     ININDNSKKDKKEKSQNLQSNNTEGENLGESDIKNFEKISLGDNLSYVLSSIGKPGRI
                     DISEYGFDWYVYNQYGKEFAMVGLENDEVVALYSNSINSCENQDIKLNQDRQTVRTKI
                     TPLKYKRKGNTRYIINSENQYDIISKEGKYITIFYDIHEENRVCSYLIIDKSTEDEFK
                     NLYPDDSEELKKCFELEVIDLVNSVRNQRGLNSLRYSEQATLSSRKHSEDMRDNNFFD
                     HVNKKNETPFDRMKREGIVYTSAGENIAAGQINAIYAHEAWMNSEGHRKNILGNYNNI
                     GVGVIFGGSYKTYYTQNFYK"
     gene            complement(16487..17296)
                     /locus_tag="KR294_001810"
     CDS             complement(16487..17296)
                     /locus_tag="KR294_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239890.1"
                     /translation="MNLSKEYVNLYDNYLKYINEVNKEIRSIKNMKKRVLKRGDFAPE
                     NEVLELEGKTIRDIDDVDTKKPKNKIYKFSNGDVYVGKFLEGKMEGKGSYTFFVDEGT
                     VMEYIGEFKEDKKNGKGNFIFSNGNEYIGYFEEDMMSGIGNMLYSSKDEYIGTWKNGK
                     KDGKGIYKWSDGCIYAGEFKGGKMEGYGICYNSKGEVLYEGEWKNNLIHGKGTYIWEK
                     GKKYIGEFMHGKKHGQGTFYLNNELVYEGTWKFDKPSIFDRTLDEIFSLRL"
     gene            complement(17538..18404)
                     /locus_tag="KR294_001811"
     CDS             complement(17538..18404)
                     /locus_tag="KR294_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBH0239891.1"
                     /translation="MSEVKNTLQKHPVLRYSTMLFGMLMTSIGINGFLRPAHLLSGGA
                     TGIATSINYLTNINVGLLTFLINIPIFILGFIYLEKEFCISSLVNMIVFSLLLGATQE
                     ISNIIPIHDILLQSVYGGILSGLGVGVVFRTRSSQGGTDIIAAILKIKKNIEMKDTAL
                     AINGLIVLTGSFLFGLDLALYTLIGLFLNAYSMSFIKDAMNYQKSVMVMSNEVDLIAE
                     DIMKSLVRGVTFLDAEGAYTHQKKKIIYTIVSSNEIPKIKDIALKYDKKAFISVNDVT
                     EVKGRGFKAKDL"
     gene            complement(18924..19613)
                     /locus_tag="KR294_001812"
     CDS             complement(18924..19613)
                     /locus_tag="KR294_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HBH0239892.1"
                     /translation="MYNVLQTPVFGIIVTIVFFNLGRYIQRKTSNPICNPLLIAIVGI
                     ILFLSISKIPYENYKIGADSLNFFLGPVTVVLAVPLYKQFELFKKHMFEIIVGIGCGI
                     VISFVSVLIIGKIANSDVSIINSLIPKSITTPMGISLANSLNGVESITVVAIIFTGIF
                     GGMVASTVFKLGNINHPVAKGIALGTSAHALGTTKAFELGEIEGAMSGVSIGVSGTIT
                     VILIPIIMNFI"
     gene            complement(19606..19977)
                     /locus_tag="KR294_001813"
     CDS             complement(19606..19977)
                     /locus_tag="KR294_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HBH0239893.1"
                     /translation="MKVFNQLVIILSIWVIGEYISSFIQGIILIPGSIVGMLLLFLLL
                     QFKVLDLSSIENVSGFFLDNMAIFFIPAGVSLIKSLDLIRENVLVLLLVICLSTLIVM
                     YTTGIIVEKMIKKKEEGQKNV"
     gene            complement(20159..21505)
                     /locus_tag="KR294_001814"
     CDS             complement(20159..21505)
                     /locus_tag="KR294_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBH0239894.1"
                     /translation="MPRKILDISLIEDNKSDLTFFNIEEEDGDETLKALKQSYVTTNY
                     KEETLLNLQGALNSKSDTTSKELKLESYKRYNNALDLAYKNYITSAINMVNKALEINP
                     KDIDILNLRGLLKLLKCDFAKSFESFYTALCYENNHISRKYVNLISSEDFKTFLGRYN
                     HSIRFINEELNYESIHILENIIEEEPELIEPYVILSLLYDKLGNVKKREGYLDKLKEL
                     DKDNPVFEKNEEEKEDTSKKEEIKKVKRKKSILPYIIVGCVLIGMGIYLIQSKKRIEN
                     LNNQISSKEEKLSETDKKLGETSKKLEKTNKELNEVKNKEPEREITVADEEDLYYQAL
                     NLKKNKEYEKAIDNFKSVVSSGKTKKYISESIYQLAITNKLLGNKDEAIKYYKKYINT
                     YTKNDQYYDDSYYELGMFYYDNGDLKNAQQTFYSLRSEVPDSMYNNSKIKEILSEK"
     gene            complement(21687..22280)
                     /locus_tag="KR294_001815"
     CDS             complement(21687..22280)
                     /locus_tag="KR294_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fis family transcriptional regulator"
                     /protein_id="HBH0239895.1"
                     /translation="MNLNNITNYVQSICENISNVLDVDVTLVTKDLTRIAGTGIFRGK
                     IGETISEKSVYSLVLKDGKSYVINKEIEENCNKCANRENCKELADICTPVKMGEHILG
                     ILGIAAFNEEQKEKILSKDKELTAFVRSMSDLISFKLDELYKQEVKTIDDLEREAIEN
                     AIKKYGSNTEGMKKVAEALNIGIATLYRKVKKFNIKS"
     gene            complement(22345..23814)
                     /locus_tag="KR294_001816"
     CDS             complement(22345..23814)
                     /locus_tag="KR294_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanW family protein"
                     /protein_id="HBH0239896.1"
                     /translation="MSNVNKKLVIAIGAVALVVIIFIGIMCMQFKGEKIAKNTYVNGV
                     NIGKLTKSQAKQELAKKYKLENVDFNYNDKSWKVKSKDLNLSTDLDKTVENAYNLNRK
                     SAFFGNLSKTISANFGKKSNLVVAINYDKNKLKAEMEKIAKEIDVDVKDATLDISGEK
                     VKVIPDSDGLKMDISKSMENFDNQTKKGNYKNELVVKATPAKVKKEQLANIDTNLGTY
                     STTFKTSQINRSINIKLATDNISNVLLMPGETFSFNKHTGKRSKENGYKSAPVIMEGE
                     MEEDYGGGVCQVSSTLYNSVLYAGLEIVNVKNHTIPSSYVPKGRDATVADSGIDFLFK
                     NNLKHPVYIKNYVSGNQIVCNIYGSAEDKQNITISTKLDGVSQTTMKRVNDPTMPKGK
                     EKVDKSGRNAYSVSTYRTFNDANGKKIKTEKIANSYYPKKEGIILVGTMEPKPEEKPN
                     TDENKNNQNTNNQNPNNQQKPETPPTDNKPNETQPQPQA"
     gene            complement(23929..25320)
                     /locus_tag="KR294_001817"
     CDS             complement(23929..25320)
                     /locus_tag="KR294_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HBH0239897.1"
                     /translation="MNFRDLFEKAVDFIDEKRKSIVAISLSTLGVIALIIVFFLSSNE
                     FSVGNEANELLKIIEKRQYSIAVDYYTSIEKKFSDSKMERFNKSVSKKINKLLLNSGD
                     KYLDGDISQESFIGLINTVKELNKISIDVDDLLAQADRVREMYKEENTTYDIAINYIS
                     TVSILNGMGSNLDVYKQNIETIKESRDVYDSAVKDQKAYKYYEAIEKYNKVLKEDEKY
                     YSMAQNGKEQCIEEMYDYYISRAEEANTSGDYERALQYIEYLKDDYSDDEKVQSLEKK
                     YKKNLSLYTLTSDDIINVIAKKSGKDKANLSINSLPQMIKNNKYYYAEVYEYDKLINE
                     VLVSAKTKDLYSYKDGKKDYKVDYGDGYFRILEDGSYQFGITKDKAKFVLTNTLDEKE
                     NKYKKIEILDIEKADRYVKSKKSLEELFGKYKNIYYYAVVNKGLFRGKEVYAINIYNE
                     KIYAISENGLNEY"
     gene            complement(25486..25734)
                     /locus_tag="KR294_001818"
     CDS             complement(25486..25734)
                     /locus_tag="KR294_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239898.1"
                     /translation="MMICFAMTFALVLINSVMGVHIGLDYYFLMGSVLTVCLTIGIVL
                     CNARKIFDSKAIHKTRTKTVSNNKKQKSHSRDIKRKIS"
     gene            26000..28129
                     /locus_tag="KR294_001819"
     CDS             26000..28129
                     /locus_tag="KR294_001819"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HBH0239899.1"
                     /translation="MPNLPSLGSKAPDFKANTTNGPIRLSDYKGNWIVLFSHPGDFTP
                     VCTTEFLCFAKYYDEFKKRNTELIGLSVDSNSSHLAWMYNISLLTGVEIPFPIIEDRD
                     MRIAKLYGMISKPMSDTSTVRSVFIIDNNQILRTILYYPLTTGRNIPEILRIVDALQT
                     SDRDNIVTPANWFPGMPVILPYPKNYKELKNRVNSCNKKYSCMDWYLCFVPDNYNDEE
                     VSKKIDNTCSWKKEHTKNIENECNCEHEHHDYLNKALDCKQEHKTDIKDDCNHEKKHT
                     KNTNKVHNSKQDKFKDKSCDEMNFNYDKDESCDKINSSYNKEDSSYEDFYKHNYKNYD
                     YTSEKNTKKIAMKTLKDSKKLVRPQITDPYNPIVENANCPDINPIVAEYVLGNPTNVD
                     AQLLDAVIFAFAEIDQSGNLFIPYPRFLNQLLALKGEKPSLKVIVAIGGWGAEGFSDA
                     ALTPTSRYNFARQVNQMINEYALDGIDIDWEYPGSSASGITSRPQDRENFTLLLTAIR
                     DVIGDDKWLSVAGTGDRGYINSSAEIDKIAPIIDYFNLMSYDFTAGETGPNGRKHQAN
                     LFDSDLSLPGYSVDAMVRNLENAGMPSEKILLGIPFYGRLGATITRTYDELRRDYINK
                     NGYEYRFDNTAQVPYLVKDGDFAMSYDDALSIFLKTQYVLRNCLGGVFSWTSTYDQAN
                     ILARTMSIGINDPEVLKEELEGIYGQF"
     gene            complement(28386..28985)
                     /locus_tag="KR294_001820"
     CDS             complement(28386..28985)
                     /locus_tag="KR294_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease H family protein"
                     /protein_id="HBH0239900.1"
                     /translation="MAKQKFYAVKKGKNIGVYNTWDECKKQVNGFSGAEYKSFSTFQE
                     AKEYIDGSEKLSFQEDKEFIEAYVDGSYEHSVKMYGSGVVILKNNEVIKTYSEKGKEK
                     TLVSMRNVAGEIEASKIAMQYCIDNNVQNLILYFDYEGIEKWCTGVWKTNKEGTIAYK
                     NFYDSIKNKLNVKFTKVKAHSGNKYNEEADKLAKKAIGV"
     gene            complement(29003..>31704)
                     /locus_tag="KR294_001821"
     CDS             complement(29003..>31704)
                     /locus_tag="KR294_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HBH0239901.1"
                     /translation="LTNCNSKVENRALSDAIDIINIVNCLLVKFNNYEKTTLEPLSFK
                     INSYLKKFNLPTWEWSKFLEEANYDLSNNINIKKEYNIFDSKEEKKKERETLKILNEE
                     EKNYEELLKYKTIWENKEGFTYEYRPGQYELTKTIRELFRNSEDEEKIACIEAPTGIG
                     KSVGYLLPAILEARINKKRLLISTDTKELQIQLINKDIPNVLDSLGLNGKVSYGYIKG
                     KNNYICIDRLEAYIDDYESQNPTKGEILSLIFLKRLVEGGKYGDIEEINYLVFDNFKE
                     ISTHLRNVSCDPNMCRPKKCKKDCLYKNRIEELKEEHITVVNHSLLAKWPYKDEKPLE
                     NIIVDEAHNLTEKGYDFFSSIINSKSLRYLLQEIYPYEFIQNSSFIYKKYSRNMRKIK
                     AFDKFYNVLKIGREDKQKIARSINLIIEEIDSILKFGNCNEYNNVSNYNLRWELNLQI
                     DEIVGKLKKDGIDTEISYRAYSEKIKLSCEKIIKNLVSIIIIIYRNIDDDSIDKEADI
                     YKFGKAKTRDLEDIKIIFEIFLEYDEKDDYARIVEIDKNYNDFEFRVVPLKIADLFEE
                     NILSQLEKGIFLSATLSLSESMSYFKNTLGIDRVKNVEKIIEPIFDYKNRVSVVGFSD
                     ICEYRNSEFPNEMSKIISNISKITEGHTLALFNSKDRQEKTYEILKKYLHSFNLEIYA
                     DKKGIRHLNDLNRKCVVLGSKGCFEGVDIPGDGLVCVTLDKLPNLNPKDPLYFTIMKK
                     YGIDYYTINYPQMTIKVKQAMGRILRSKYDYGCFVIFDVGTNISVLKRLEKDLHDCKI
                     SKVNSNEFYTYIRRHLNKYRSLILKSVIFDTIKALNVDAKMDNNDVDKDIIKKDINEN
                     IRQRAVKGEVYHIDIIKKDMKVKYFDRNYLINLDIFMREEDKN"
BASE COUNT         9968 a         5573 c         3214 g        12949 t
ORIGIN      
        1 aaaaaaattt aaaataatct atttaatacc gatactattt actttgggaa tgagtatttt
       61 tatagcattt aattataatc aattgccaga ctcaattgcc actcattgga acataaatgg
      121 gtctcctgat gtttttatag ataaatcatt tcttaatgta tttaaattaa tcggtactga
      181 cttttgttta atggttttat tatatataac ttccattgga tccataaagt caaggattaa
      241 gatagataca aatagaattg aagaaagtag agttgaaaac attaaatatt taaataaaat
      301 tggttatttg tttttaatat tgatgattat aatgacaaca cagtttttta ctactctttt
      361 atcaataaaa acaaaactat caactgctat gaatattaca acgcttttag ttataattta
      421 tttaatagca acatatatta attccccaaa tttaaaattc aactcatctt attctccaga
      481 agaagatgag aagtattgga tagcaggcat catgtataat aatccaaatg acccatcatt
      541 aatggttaat aaaaggtttg gtattggatg gactataaat tttggcaatc ctcttggaaa
      601 aatactatat attgctatag ctttactttt aattttttca ttgtttagcc taataaaatc
      661 tctcttactt taaaatacca taaaaggtat cttacttgta ttattgggta ttatattttg
      721 taggataaga aatatttcat attatcgttg aagtatagta tttatatatt actaagaatg
      781 gagattttca taatgttgtc aaaagctgaa atcaaatatt ttaatgaatg tgcttctgag
      841 atactttctt ctgaaaaagt tcaacttatg agaacatttc ctcatcatgg caatgtttca
      901 tgtcttgaac atagtttgtc agtagcatat tatagttatc tattatgtaa aaaattgcac
      961 ttaagtgttg atattcaaag tgttattaga ggagctttac tacacgactt ttttctttat
     1021 gattggcatt acaaaggtga tagaaaagga ttacatggat ttactcaccc tagagaagca
     1081 ttaaaaaatg caactttatt ttttcaaata aatgaaaaag aaacggacat aattttaaaa
     1141 cacatgtggc cacttactgt taagccacct agatacaaag aagcatttat tgtatgtttg
     1201 ttggataaat tttgctgttt agttgagact ttaaagatac attctttatt atctccttac
     1261 catgtatagg acaattccca caacactttt ataacttaat tttgaagagg tattaagtat
     1321 tatattcaac ttgatacctc tttactattt attattttat ataataatat tttctttata
     1381 atatagttat aaataacaac ttctaccctc gataacttcc ccttcttata gacatgctta
     1441 ctatcttaaa taacaagaaa ccagctatta aatttattag tattgtttat actactctaa
     1501 caataatatc ataaataaac ctccaaatag cttctctttc actacctttt atcttaaact
     1561 atattttttt cttaaaattt gtaaaaaaca tagcataatc tttataaatg ttctaaaatt
     1621 taatttaagc atcaaaatta gaaaggatga tattatgttt aaagaaatga gattgaaaaa
     1681 aagagaaatg acaaaagaag atactgttga agtattaaaa aatggtgaat ttggtacttt
     1741 ttccactata tctgaaaatg gttatcctta tggagttgct gtaaattatg tatactttaa
     1801 tgattctatt tactttcatt gtgcaagaaa tgggcataag ttagataata tatcgaaaaa
     1861 caacaaagtt tcttttttag tagttgctaa tgaaagtgtt attccagata aatttagtac
     1921 tacttattct agtgctatag tttttggaaa agcttgcact gtagaaaatg aagaaaagaa
     1981 aaatgctctt gtagaaataa taaaaaaata ttctaaagga ttctttgaag aaggcatgaa
     2041 gtacatagag aaggatatga acttaacaac tgttgttaaa atagaaattg accatatttc
     2101 tggtaaagct tcacgtttat aattaagtaa aaatacctaa aagtatatac agtcgctttt
     2161 aggtattttt atatgatatt cttatatgtt aagtcttttt aggtaatctc ttatacctat
     2221 cttggcatca tcatttggtc ttatatcaga attatctcct gctatatgaa gtattccata
     2281 cgctggataa cctcctctta ctgaacatgg aactgacaaa agagtcattc ccatatgttg
     2341 ggcaaatata ttcatagctt gcaaagctaa ttctcctcct ccatgttgtg aacctgctgt
     2401 agcaaaacaa ccaaatattt taccactcaa aggagtacct acccaaatat cagaaaaact
     2461 atccataaac atcttcattg gtccagatac atttccataa tatgttggtg aacccataaa
     2521 tatagcatca taatctaata tttcttttcc agatttaatt acatttatac tttcaaattc
     2581 gtctttgtat tctttggaat ttatcaaata atattgagga agtgtttttg caacttcgtc
     2641 acttactcta aatatatcta cctcgatatt catttcttca agcgcttctt tatattctct
     2701 agctaataaa tatgtactcc cacaaacact atgaaaaatt actgctactt tcatcattat
     2761 ccccctaatt aaactcaaat ttatttttta tatagtattt ttattatcaa acactgctaa
     2821 atagtactaa atggattcaa atatacatta ctttttatta cttcaatttc actaaattca
     2881 tctaaaaatc tcttcataac atttttgaat atatcttctg tatcaaaatg accacaatcc
     2941 actatacaca ttccaatatc aagtgcatct tgtgcctcat gatactttac atcacccgta
     3001 attagtactt ctgcaccttg tctcttagct ttttttacaa attctgaacc agctcctgtt
     3061 acaacggcta ctttcgttat gtctgtacta aggtttccaa ctactcttat gtgtttcata
     3121 tttaatttct cttttatttt ccttgaaaga ctttctaatg tcatactttt atcaagttta
     3181 cttattctac ctagtccaaa tatctcacct ttattttcta acttgtacaa atcatatgca
     3241 acttcttcat aaggatgtgc atctaacata gaacttatta ccccacctaa aagcttctgt
     3301 ggtactacag tttcaatttt aacttcattt acagtttcta tatcatttac acttccaaga
     3361 aacggattag agccttctaa tggcttaaat tgtccttcac cttctattga aaacgtacaa
     3421 tcactataat tccctatatg acctgctcct gaattactta aaacctttct aagttcatct
     3481 gaatagttat gtggaacgta tactgctaat ttatacaaat tttcgctttt agttatatct
     3541 aaaacctttg aattaccaaa ttccataatt tccataaaat agtcatttag accatcaaat
     3601 gctatatcaa aattcgtatg catagaataa agtgatatat catttttaat aagtttttgg
     3661 ataagtctgc cttttaaatc tccactatta attttattaa ttttcccaaa tataaaagga
     3721 tgatgtgtca caattaaatc tatatttttg gatatagctt catcaataac atcttcatta
     3781 gcttctaaag ataccaatac cttttttaca tccatatcaa aatctccaac tataagacct
     3841 acattatccc aatcctctgc taagtttaga ggatactttt tttcaatttt tctagttaga
     3901 ctctttaata gcatatatac ctcctattta ttttattaaa ttttcaagtt tttttattgc
     3961 aacttcgctt tcctttctct tcttatctat agcttcccca tttttccctt ctaatttatt
     4021 aactatagaa ctatatgtct ttatcttttt ttctataaaa tcattaaaaa gagaatcttt
     4081 gttttctaaa agctttattc caacctcata atatatctca tcttctatta tagtattttt
     4141 acctgtatat ttggcaacaa ttatctcata tattctaaaa tcttctctca ctaaaacttc
     4201 ttctaaaatt tcatatccgt tgtttaaaag gtaatatcta agttcttctt gtgcttgcat
     4261 tggctgtaat attaattttt ctacattatg tgctacttct tttttagcct cgagaagctc
     4321 acttatcaag attccaccca taccagcaat tatcacttct tctacttccc ctatttcaag
     4381 tatctctata ccagaaccca atcgtaaatc aactttatct aaaagattgt tctgtatgac
     4441 ttctttatgt gcattgtcaa gaggtccttt attaacatcc gctagcactg caaatggtac
     4501 ttttccctct tttaacaaat atactggtat gtatccgtgg tccgtcccta tatcagctat
     4561 ttttttacca tctgacacta atgatgctat tttcaataat ctatctgtta atttcaaata
     4621 taattctcct ttcaattccc tttatttata ggatttaatc caagttatag atattagact
     4681 gaaataacta caaaaataaa attaaatctt tactacaaaa tagccatgag atatcactta
     4741 tctcatggca tttatcacaa aaacatcaat gatgtatctt tttagtctaa ataatctcta
     4801 agtttttttg atctacttgg atgtcttagt tttcttagtg cttttgcttc tatctgtctt
     4861 attctctctc tagttacatc aaactctttt ccaacttcct caagagttct ggctctacca
     4921 tcctcaagac caaatctaag ctttaatact ttttgttctc tatcatttaa tgaaccaagt
     4981 acatcttcta tttgttcttt taataaagaa tatgctgctg cctctgctgg ggctggagca
     5041 tcatcatctg gaataaagtc acctaaatgg ctatcttctt cttctcctat tggtgtttct
     5101 aaagacacag ggtcttgagc tattttcatt atttctctta ctttatcttc tgtcatttcc
     5161 atttcttttg caatttcttc tggttttgga tctcttccaa gttcttgaag tagttgtctt
     5221 gatactctta ttagcttatt tatagtctct accatatgaa ctggtattct tatagttcta
     5281 gcttggtctg caatagcacg tgttatagct tgtcttatcc accatgttgc ataagtacta
     5341 aacttatatc cttttgtata gtcaaatttt tcgactgctt ttataagacc taaatttccc
     5401 tcttgtatta aatccaagaa aagcatacct cttcctacat atctttttgc tatacttaca
     5461 actagtctta agtttgcttc aactaacctt tgttttgcta tctcatcacc ttcgtgcatc
     5521 cttctagcaa attctacttc ttcatgtggt ttaagtagag gaatttttcc tatttctttt
     5581 aagtacattc ttacagggtc atctatactt atcccttttg gtaaagataa atccacagtt
     5641 tctatttcta ttgcagaaga gtcatcatgt gaaattgcct ctgcatcttc atctaagtgg
     5701 cctatactta aatcgtcatc agcaaccgaa aaatctatat cagctttata gttttttgtt
     5761 tctgttattt ctattcccaa atttcctaaa gtctcataaa gattttctac ttgatcctta
     5821 tcaagttcag tctccgaaaa agcttccatt atctctgcaa gtgtcagaga accttgcttt
     5881 tttccttttt ctattaatgt cttagcagta acctttttta actctttttt attcgattta
     5941 ttttccacac tcaaacctcc tttctctaca agctctttaa aattttattt atctcaacta
     6001 tttttaaagc aatttccata actctaccat ctacctcttt catatcatta ttattttcta
     6061 attcttgttg ttctctcaac aagctattaa tttgctcttc taatgagttt tttctgatat
     6121 ttgttattat tccttctatt tcttttgtgt tctctaagtt tatactattc aaagaaattg
     6181 aatttaattc ttttaagtat tcttcggata tgtttaaact tttcaatttg tcaatagtta
     6241 ttttgtccaa ttcttgattt ttaatcatgt aatttaaaat ttctttactt tctttcaata
     6301 aaaaatcact ttcttctact ttaagtaacg ctatttctct aatttttttg tcttctaaca
     6361 ttatttttat tagagtttct tcaactaatt gttttccgtc ttgtctgact tcgacttttt
     6421 caattacttt ttcttctatt ttcttttgat ttttgttatt atatggctta ttgtaatttt
     6481 taccataaac ttctctcttt atagactcga cattaatatc tatttgattg cttaaatact
     6541 ttgtataaaa atcaatttca acaggacttg tcaattgttt tataatttta gaagcttctt
     6601 ttgcgaactt cactcgttct tcatcttttt gaatgttaaa ttctttttta agatgatcta
     6661 ttttatattt tatgtagtga gtagaaacat ccatagcttt tttataatca ctaagtccgt
     6721 attttcttac aaattcatct gggtctttag catcttttaa gtctaacact tttacattga
     6781 tacctaattt agtaagtata tctatagctc ttaaagtcgc ttttattcct gcttcatcag
     6841 aatcataaga tataatagca gtgtccgcat atctctttat taaaatgcct tgttgttcag
     6901 tcaaggctgt tccaagggtt gctactacat tttttatacc atactgataa agcgaaatta
     6961 aatccatata tccttcaact aagactatag ttttactttc taaatttttt ctagcaaaat
     7021 ttaatccgta taagttctgt tttttattaa aaattaacgt gtctggagaa tttaagtatt
     7081 ttggcaaaga atcgtctaat actcttcccc caaatcctat tatatttcct ctataatcga
     7141 atataggaaa cataactcta tttctaaatt tatcatagca attagttcca tctctatttt
     7201 ttgcaattag accgcactcc aataagtctt gttttttata tcctttactg attagagtat
     7261 tcataagtga attccatgaa tccaaagaaa atcctaaacc aaatttctta ataattttat
     7321 catctagtcc tcttattctt aaatattcat acccaagatt tttgcttccc aataagtttg
     7381 aaagataaaa tctagctgct tccgtatgaa tatcttgaaa tttcttagat ttttctattt
     7441 taatcctagt ttcttcattc atgttagtgt taatttctat accgcattta tttgctaaaa
     7501 tttttacagc atccataaaa tccaaatttt ccattttcat gacaaaattt attacgtctc
     7561 caccttcacc acaaccaaaa cacttataaa tctgttttga cgtatttata taaaaagaag
     7621 gtgtcttttc gccatgaaat ggacataatc ctttgtaatt agctccagat tgttttatat
     7681 tcatatattc agatattata cttgctatat cgcatctagc ttttatttct tcaataatgt
     7741 cttttatatc attcatatta tcaccttctg gtgtaatttt ttgtgttaac atttctattc
     7801 tacactatat tctaaatttg tcaatcactc aatatacaca attcgacttt ttttattgat
     7861 atccttctta ttaatcaaaa aatttttatt ttttatatta attctatcaa tattaaatct
     7921 ttatttatat taaataatct aactatcaaa ttataactta taaatttacc ttagcaacga
     7981 ttacgaataa aaaagaggct cttgcctctt ttaataatta ttaattgatt tcattaaatc
     8041 ttcaaattca ttaaagcaaa gagattgagc accatctgac aaagcatttt ctgggtcagg
     8101 atgtacttct accattattc catctgctcc acatgcaaaa gatgccagtg acataggttt
     8161 taccaaatat ctaactccag tggcatggct tgggtctacc acaacaggaa gacctgtttc
     8221 cttttgaata atgggtactg cagctaaatc taatgtattt ctagtataat cattatacgt
     8281 tcttatacct ctctcacaca ttataatatt actatttcct tctattgcta tatattcaga
     8341 agcacctatc cattcagtaa ttgtggaagc tattcctctt tttaacataa caggtttatt
     8401 ttgttttccc acttcactta aaagagtaaa gttttgcata tttcttgacc caatttgaat
     8461 tatatcactt atactataca gttcgtccat atctcttaca tccataagtt ctgtaataac
     8521 agccatacca acttcgtctt taaccgcttt taatatttca agaccttctt tttttaatcc
     8581 ttgaaatgaa tttggagatg ttcttggctt gtatgctcca cctcttaaaa tatttgctcc
     8641 ctgacttttt acaaatttag cagtctccaa aagttgctca taactctcta ttgcacatgg
     8701 tccagctatt ataagtttat ctttttttac agttatcttt ttgttatttg tatttatctc
     8761 tatctttgaa ttattattaa ataggttttc tttcataacc tacaagctcc tttacttctt
     8821 ctctttcttc agcagatagg aggtttaaat gttcttttat tgttttttca tttattataa
     8881 gttcttcatt taaatccata agtggtatca aaacgaaagc tctatcttga atccttggat
     8941 gaggtattgt tagtctttca tcagtggaaa ctacatcatt aaaaaatagt acgtctacat
     9001 ctatagttct tggtccccaa tgaactattc tctctctgtg tagttctctc tctatttctt
     9061 gacaatattc taacaactca taaggttcaa actctgtttc tatttctaca cacatattta
     9121 gaaaatctgc ttgttctgta tatccccatg gttttgtttc gtataagctt gattctttta
     9181 ctttatatat agaatcacta tttttcaaaa gttcacatgc tcttgataaa ttatcaaatc
     9241 tatcacccat gttagtacct attcccaaat aagccttatt catctcttgt tctccttatc
     9301 tcaacaccaa aatagtcata aataccattt acaggagcct caggctttct aactctgacc
     9361 ataactccat ttataagtat aaatttattc aagacttctt cagcaatatt ttccgctaaa
     9421 gcctccaaaa gattaaattg tttattttca gtaatatctt taacaacatt gtaaacctcg
     9481 gcatagctta cagatttatt tatatcgtca ctaagacctg cttctcttga atcaatataa
     9541 agttccatgt cgacaaagaa tttctgacct agaaaatttt cttctttaag aacaccatga
     9601 tatccataga atcctagatt actaagtaat attttatcca ttatattata cctactttct
     9661 atatattgca tcagtcattc tagctgccat taaattttca taaacatcat gtactctaac
     9721 tatatctacg ccatctctta taccaagaac agtagtagct attgtacctt ctaatctttt
     9781 tttaggctca actggaagta cttttcctat tactgatttt ctggatgtcc caagcaaaat
     9841 aggataccct aaatctttta attcatttaa tcttctcaat acttcaatat tttgttcaaa
     9901 atccttgcca aatcctacac ctgggtcaag tactattttt tcttttttta caccacaact
     9961 cattgccatt tctatactta ccttaaaaaa gtcttttatt gactccatta tatctttgtc
    10021 atagtttgtc ccatcttgat tatgcattat acacacttct gcatcatatt ttcctattac
    10081 agaagccata tttttatctt ttctaagacc ccaaacatca tttaccatag tgacacctaa
    10141 ttttaatgct tcttctgcaa catctgcctt ataagtgtct attgatattg gtatatccaa
    10201 ttcctgttta agttttttta ttacagggat tactcttctt agctcttcgt ctgagtctac
    10261 atagctatga cctgggcgtg tagactctcc tcctaggtct attatatctg caccttggtc
    10321 aaccatatct tttgcatgtt gtattgctat gtccaagtta ttaaaatctc ctccatcaga
    10381 aaaactatct ggagttacat ttaatattcc cattatataa gttcttttac cataatcaaa
    10441 cacaattaat gacactccct taaattaaat tttatctcaa taaatgatta tatctataat
    10501 aaattactac ttcatagtaa tcaaactcat agcctcggct ctagacgcaa tgtccttttc
    10561 aaatattcct ctcactgctg atgtaacagt ttttgaacct ggttttttta cgcctctcat
    10621 tgtcatgcac atatgttcag cttctactac tactaagaca ccataaggtt gtaattcttc
    10681 cattattata tctgcagcat ttttagtgat tctttcttgt aattgtggtc tttttgccaa
    10741 tgtatctatt actctagcaa gtttagaaag ccctgtaagt cttcctcctt ttggtaaata
    10801 agcaatatga gcttttccaa agaaaggaac tagatgatgc tcacaacatg aataaaatgg
    10861 aatatctttt accaatacta actcttcatg tttttcatct gcaaaaagaa cttttaaatg
    10921 gtctcttggt tcttcactaa gaccagagaa tatctcttca tacatcctag caactctatt
    10981 tggagtttcg attagacctt ctctatctgg gtcttcccca attgcctcta gtatttctct
    11041 tactgcatgt tgtatctttt ctttatcaac tttattcatt taaactcccc ccattgattt
    11101 gtgactagaa gattagtttt ataacctctt ttgtctcaat ttctttaaaa atataattat
    11161 aaacatctaa aagtctttga tagtcataat tttcacttac ttttgacact agttcaaaaa
    11221 gctcattatt ttcttttttt aaaactttta gcaatttttt gtcttttggt acccatttat
    11281 catttatatt aaagtaccca attattatat cttttaaata taaattcgtc aaaaaatgat
    11341 attcaaaaac atcaaatttt tctttatttt ttaaattcaa tatttttgct ccaatatctt
    11401 gctttataaa agacttttcc tctaatgaca ttttactagg tccttctaag taaatatctc
    11461 tacttatatc ttttataata tgtgatatat tctccctatc aaacagtact ttagcatctt
    11521 tcatttcttt cacaaagaaa tattccctat ttgataataa tttttttaca ccatcttttg
    11581 aaaagtaatt tacatcaaat tctattccct tttttttaaa cagtattctc tcttgttttt
    11641 ccccttcttt tacaaaaacg aacacatcaa tatcgtttat cactacatca taaagagtaa
    11701 aatctacatc tttactagaa cccactaaat atacagccaa agtgttttgg ttttctatta
    11761 ttttagtcat ctcttcattg tatacttcat aaatacaacc tatcatcttt tgtctccaac
    11821 aaattgttaa tattttaatt tattctaata acttcactat tttatcaaaa acaacatttt
    11881 ctttattaaa ttttattttg tcaatttctg taacctttat agcgcccata agactatttg
    11941 tgacaaaaac aaaatcaaaa ctactaattt ctgatatatt aatttcattt tctatcaact
    12001 ctatatgtaa ttcgtcacaa atctctataa tccttttttt tattattcca tttaatatcg
    12061 gtaatctatc actaggagtg tacactcttt ctccttttat aaagaaaata ttgctcatag
    12121 aacattctaa tattacacct tctgaattta aaaatatacc atcattataa ccagtcttat
    12181 ttgcgatatt tttggtatat atgttttcaa aataattagt agtcttatgt ctatgaatta
    12241 aactattccc cctaactatt ggagatatag ctaatttaaa ccccttctca tacgtctctt
    12301 gattatatgg aatatcccta atagatatat tataaccttc atcaaaaaca gtaattctaa
    12361 gtgctttatt aatgacattt tcttttttta tatatgtaac aatttcattt atcaagaaat
    12421 cttttttata gtttatatct aaatccaaac aatttattga gcttagcatt ctttctatat
    12481 ggatatctaa atctactgct attccatttt taactctaat agtttcaaac aaaccaattc
    12541 caaatttact taaactacta tcaaaaccta cattattctt cataatatcc cctcaaagcc
    12601 ttcattatgg atttagcttt atcaagtgtt tcttgatatt cttcatctgg gtcagaatcc
    12661 caagtcattc ctcctccaac ttgaaagtag acttttttgt catttttgat tattgttcta
    12721 attgctatat taaaatccat atcaccatta aaacctatat aacctattga accagtatat
    12781 acatttcttt gcgttggctc taattcgtct ataatttcca ttgctctaat cttaggtgct
    12841 cctgttatag acccccctgg aaaagttgct tttattacat cagtagcatc tttatcatct
    12901 tttaactcac ctacaactgt ggaaactaag tgatttacat ttgcatatgg ttcaattaca
    12961 aatagctctg gaactttaac acttccagtt ttagatattc tcccaatatc atttctttct
    13021 aaatctacta tcataagtag ttcagctcta tctttttcac tatttctaag ttcttgttga
    13081 agtcttaaat cttcttcttt atctttccct cttggacgag taccttttat tggtctagtt
    13141 tctattctct tattaacaca tcttataaat ctttctggag aatttgataa tatatgtgca
    13201 tcttcaaagt ttaagaatgc cccaaatggt gctgggctaa atcttcttaa gtccctatac
    13261 aattcaaagc ttgtaagttc tgtttctcca ctgaaccttt gtgttaaatt agcttgatat
    13321 atatctcctt gtcttatgta ctctctaaca ctttgaactg catttttaaa ttcttccttt
    13381 gtaaaattag atttaagtct tataggtgtt acttcttttt cttcataaca tatgctatct
    13441 ataccttttt tctcttcttt taatattctt tgttctatat catctattat cttttcttct
    13501 aattcgatat ctatgtttgg agtagctata taagtttttt gcacaagatg gtctataact
    13561 attacatgat tataaaatcc aaaatacata tcaggcatct caatatcatc tacagcagtt
    13621 ctaggtaaat tttctatgta attacctaaa tcataagata aatatcccac agcacctcct
    13681 acaaatggaa gattagtatc atttacaacc ctatacttat gtagttcttc ttttaaaact
    13741 tctaaaggat tttcatcagt atctttatac tttaatacct taaatggttg gctacttata
    13801 aaagaatatc ttcccaattt ttctttatcc atagcactat ctaatataaa actgtcatgt
    13861 tcatttctaa aaatagtaaa tatctcaaaa gaatttaatt tagtatttat ctctcttatc
    13921 atattacata tgtacccttt ctctagcttc tgttataaaa tttttaagca tttcatgacc
    13981 atactctgac aaaatagctt ctggatgaaa ctgtactcct tctattaaat atttcttatg
    14041 cctaattccc attatttccc ctttatcagt aattgctgta atttctaatt cttttggaac
    14101 tgtattggag tcaactatta gtgaatgata cctagtgaca tttaaaggat ttttaagtcc
    14161 cctaaaaact cctttattag tatggttgat actatatact tttccatgca caggctgttg
    14221 tgcttttata atatctcctc caaaaacatg tccaatagtt tggtgaccta aacaaattcc
    14281 tagtataggt tttttcccct taaaatgctc aacaatatct atgcaaatac cagcttcttt
    14341 tggagaacac ggtcctggag ataacacaat tacctctgga tttagttctt caatgtcact
    14401 tattttgatt tcattatttc tttttactac aactgcttcc cctaattctt ctatatattg
    14461 gactaggttg tatacaaaag aatcataatt gtctatcata agaatcatac tgtaaatctc
    14521 ccccctaaaa attattttat caactcagaa actgttacaa atttaaaacc tttttcaatc
    14581 atttttggaa taaacatatc taaagcttca actgtatcat tagttgcata atcatgcaaa
    14641 agtattatat ctccattttg tactttatta attattttat ctgcaatgct attagctcct
    14701 ggatttttcc aatctttcac atctacacct gtccataaaa caactttata gtcatgcttt
    14761 tttgcaattt ctattaagtc tttttctcta taacttccga atggtggtct aaataatgta
    14821 ggttttttcc cagttacttc cttcaaaatg tcttcacact taacaatctc ctcttctatc
    14881 tgactagaac ttaaattact tatatcagga tgattgaaag tatgatttcc tatctcgtga
    14941 ccttctttac ttgctcttac taatggttct ttataccatt ttgcatgttt tccagctata
    15001 aaaaaagtag cttttacatt gtatttcttt aatacatcta aaacttgact agtttcttta
    15061 ggatgaggac catcatcaaa ggtaattgct attagctttt tttcccttga accatgttta
    15121 atcaaaacat ttccattagt atccatcatc aaagcagaaa ctttactaaa attagatatt
    15181 aacactattc cacaaaacaa ggctactgct attaagcact tatatactgt cttttttttc
    15241 catgatgtca ttttttaact tcctttcaaa tattttagtt atttataaaa attttgagtg
    15301 taatatgttt tatagcttcc tccaaatatt actccaactc caatattatt atagttcccc
    15361 aaaatatttt ttctatgtcc ttcagagttc atccaagctt catgcgcata tattgcatta
    15421 atctgtcctg ctgctatgtt ttctccagct gaagtatata ctataccttc tcttttcatt
    15481 ctgtcaaatg gagtttcatt cttcttattt acatggtcaa aaaaattatt atctctcata
    15541 tcttcactat gttttcttga actcaaagtt gcctgttcac tgtatctcaa tgagtttaac
    15601 cctctttgat ttctaacact atttacaagg tctataactt caagttcaaa acatttttta
    15661 agttcttcgc tatcatctgg atataaattt ttaaactcat cttcagtgct tttatcaatt
    15721 attaaatatg aacaaactct attttcttca tgaatatcgt agaaaattgt aatatactta
    15781 ccttccttac ttattatatc atattgattt tctgagttta ttatatatct ggtatttcct
    15841 tttctcttat attttaatgg tgtaatctta gttctcactg tttgtctatc ttgatttagt
    15901 tttatatctt gattttcaca tgaattaata gaattactat aaagtgctac tacttcatca
    15961 ttttcaagtc caaccattgc aaattctttt ccatattgat tatatacata ccaatcaaaa
    16021 ccatattcac taatatcaat tctaccaggt ttgccgatac ttgataaaac atagcttaaa
    16081 ttatctccta agcttatttt ttcaaaattc tttatatctg actctcctaa gttctcccct
    16141 tcagtattat ttgattgtaa attttgactt ttttcttttt tatctttctt agaattatca
    16201 tttatattta ttttgtctaa aaattcattc catatttcac tttgaaaaaa cttttctttt
    16261 aaatcatatc cttcttttaa taattcagga ctataaaata aaacaataag tactactaac
    16321 actaaagcaa ttaatctctt caatatatct ctccttctta aaatcaatca aaatttttta
    16381 atattgcatt tattaagtta atattgatag tgtatactaa tcaatatcat tcatacctat
    16441 ttacagtaag tattagaaaa aagctttatc tactaattag ataaagctac agtctcaagg
    16501 aaaatatttc atctaatgtt ctatcaaata tagatggctt atcaaatttc caagtccctt
    16561 cataaaccaa ttcattattt agataaaaag ttccttgccc atgtttttta ccatgcataa
    16621 attcacctat atacttttta cctttttccc atatataagt tcccttacca tgaatcaaat
    16681 tattcttcca ttctccttca taaagtactt cccctttact attatagcaa ataccgtacc
    16741 cttccatctt tccaccttta aattcacctg catatataca tccatcactc cacttataaa
    16801 taccttttcc atcttttttt ccgtttttcc aagttccaat atattcatct ttactactat
    16861 ataacatatt tccaataccg ctcatcatat cttcctcaaa ataacctata tattcatttc
    16921 catttgaaaa tataaagttt ccttttccat tttttttatc ttctttaaat tctcctatgt
    16981 actccataac tgttccttca tctacaaaaa aagtatatga gcctttcccc tccatctttc
    17041 cctctaagaa tttccctaca tatacatccc catttgaaaa tttatagatt ttattttttg
    17101 gtttttttgt atcgacatca tctatatcgc gtattgtttt tccttccaat tctaatactt
    17161 cattttccgg agcaaaatcg ccccttttta aaacacgttt cttcatgttc tttatacttc
    17221 taatctcttt gtttacttca tttatatatt tcaaataatt atcatacaaa ttaacatatt
    17281 ctttagataa attcataatg ccattcctcc aacgttattc ctaggtattt tactaaatct
    17341 attaaattta ttatatccta atagtggtca tgttttctac atattaagta attttttcaa
    17401 ttttaatttt aaaatgatat cttttaaagt gatacacaaa tcattaataa aacctttatt
    17461 ttcgtatact aaatttaaat aagctgagag atataatata caaatttaca ttataaactc
    17521 ccagcttgta aaattttcta taaatctttt gctttaaacc ctcttccctt tacttctgta
    17581 acatcattta cagatataaa ggccttttta tcatacttca aagctatatc ttttatcttt
    17641 ggtatctcat ttgatgaaac tattgtatat ataatcttct ttttttgatg agtgtatgca
    17701 ccttctgcat ctaaaaaagt tacacctcta actaaactct tcattatatc ttctgctatt
    17761 aaatcgactt catttgacat taccataaca gatttttggt aattcattgc atctttaata
    17821 aaactcattg aatacgcatt tagaaataga cctataagag tgtataatgc taaatccaac
    17881 ccaaataaaa aacttcctgt aagtactatc aagccattta ttgctaaagc agtgtctttc
    17941 atttctatat tcttcttaat ttttagtatt gcagctatta tatctgtacc accttgagaa
    18001 gacctagttc taaatacaac tccgactcct aaaccagata atataccacc atatacactt
    18061 tgaagcaata tatcatgtat aggtataata ttacttattt cctgagttgc tcctaataat
    18121 aatgaaaata caatcatatt taccaaactt gaaatacaaa actctttttc aaggtatatg
    18181 aaccctaaga taaatattgg aatattgatt aaaaatgtta ataaacctac atttatattt
    18241 gtcaaatagt ttatagatgt tgctatacct gtagcacctc cactaagcag atgtgctggt
    18301 cttaagaacc catttattcc tatagatgtc atcaacatcc caaatagcat tgttgaatat
    18361 cttaaaactg gatgtttttg tagggtattc ttaacttcac tcatttcttt ctcccttcaa
    18421 tctttctaaa tctttagaat tttaaaagct tactcttaca tatattattc ctgatgtaat
    18481 agataatatt tcaaataaat tttttttata atttcttgaa ctgtcatcta ttacatcatc
    18541 tattatatta tctttttcat atatgtctag tgcaatcttt tatattctaa tctttaaaaa
    18601 cgttcaaatc atctcattta tgccttaaat gaaacttttt ctagcataat atgatactgc
    18661 ttattattta acttgcaata tagtaaattt atagtatttt tttctaaata tctattttag
    18721 cagtaattta ttttatttta gcaaattcaa gtttagtaat tgtctcttta taattaattc
    18781 ctaaatgaaa tttttctttt tataatttca gtacatgatt tttttatttc attatttgca
    18841 tttttttcgt tcagttttta ttttaaattt tttttatttt attttgtttt aagtattcaa
    18901 ggtactcatc ttaattttat tttttatata aaattcatta taattggaat tagtattact
    18961 gtaattgtac cagagactcc aatagaaaca ccactcatag ctccttctat ttctccaagt
    19021 tcaaaagcct ttgtagttcc taaagcatgt gcagatgttc caagagcaat tcctttagca
    19081 actggatgat ttatattccc cagtttgaat actgtagaag caaccatacc accaaaaata
    19141 cctgtaaaaa ttatggctac aactgttatt gattctacac catttaaaga atttgctaaa
    19201 gatattccca ttggtgttgt tatagatttt ggaattagtg aatttattat acttacatct
    19261 gaattagcta ttttgccaat tatcaataca gatacaaaag aaatcactat accacaacct
    19321 attcctacaa taatctcaaa catatgcttt ttaaataatt caaattgttt ataaagtgga
    19381 actgcaagta ctactgtgac aggacctaaa aagaaattta gactatcagc tcctatcttg
    19441 taattctcat aagggatttt agatatgctt aaaaacaata ttattcctac gattgcaatt
    19501 aataaagggt tacatatagg attacttgtt tttcgttgaa tgtatcttcc taaattgaaa
    19561 aaaactattg ttactattat accaaatact ggtgtctgta atacattata catttttttg
    19621 tccttcttcc ttctttttta tcattttctc cacaataatt ccagtagtat acattactat
    19681 tagtgtactt aaacatatga ctaataaaag cactaataca ttttccctta ttaggtctaa
    19741 tgactttata agtgatacac ctgctggaat aaaaaatata gccatattat cgaggaaaaa
    19801 tccacttaca ttttctatac tactcaagtc taaaacttta aattgtagta gtagaaataa
    19861 taatagcata ccaactatac tcccaggaat aagtataatt ccttgtataa aggaacttat
    19921 atactctcct attacccaga tagataaaat tattaccaat tgattgaaaa ctttcatttt
    19981 ccacctccaa aaattaaaga gattgcttca aatcatatat ttgtagtttt atcaacaagc
    20041 aaatatcttt ctttaaaata gaaagttata atttgacaca atctcttttt aaatttattt
    20101 ttattttaat ttaataaaat acatacttgg ttgtttcaaa aaacttaact atataaacct
    20161 atttttcact taaaatttct tttatttttg aattgttata catactgtct ggaacttcac
    20221 ttctcaaact ataaaaagtc tgttgtgcat tttttaaatc gccattatca taataaaaca
    20281 tacccaactc gtaatatgaa tcatcataat actggtcatt tttagtataa gtatttatat
    20341 attttttgta atattttata gcttcatcct tatttcctaa taatttattt gttattgcta
    20401 attgatatat tgactcagaa atatattttt tagttttacc agaagaaact acacttttaa
    20461 aattatctat ggctttttca tattctttgt ttttctttaa atttagagct tgataatata
    20521 aatcttcctc atcagctaca gttatctctc tttctggttc tttattttta acctcattta
    20581 attccttatt cgttttttct aattttttac tcgtttctcc taacttttta tcagtttcac
    20641 ttaacttttc ctctttacta cttatttggt tattcaagtt ttctattctc tttttgcttt
    20701 gaatcaaata tatccccata cctattaaaa cacagccaac tataatatat ggcaaaatac
    20761 ttttctttct ttttactttt tttatttctt cctttttact tgtatcttct ttttcttctt
    20821 catttttttc aaatacagga ttatctttat ctagctcttt aagtttgtct aaatatcctt
    20881 ctctcttttt tacattacct agtttatcat ataacaaaga taaaattaca tatggctcta
    20941 ttagttcagg ttcttcttca attatgttct ctaaaatatg tattgactca taatttaatt
    21001 cttcatttat aaatcttata gaatgattgt atcttcctaa aaaagtttta aaatcttcag
    21061 atgaaattag atttacatat tttctagata tatgattatt ttcataacat aaagcagtat
    21121 aaaaactctc aaatgattta gcaaaatcac attttaataa ttttaaaaga cctctaagat
    21181 ttagtatatc aatgtcttta ggatttatct ccagagcttt attaaccata ttaatggcac
    21241 tagttatata atttttatat gctaaatcca atgcattgtt atatctttta tatgattcta
    21301 attttaactc cttagacgtt gtatctgact ttgaatttaa agctccttgc aagtttaata
    21361 gagtttcttc tttataattt gtagtcacat aactctgttt taatgctttt aatgtttcat
    21421 caccgtcttc ttcttctata ttaaaaaaag tcaaatcact tttattatct tctatcaaag
    21481 atatatctaa aatttttcta ggcatgcttt ctatgtcttg ttttatatct ttaactaaaa
    21541 taatactcac ctccactcta aaatatatat ttaagataac atatttaata tgtcaagtca
    21601 aaactataca tatttttcca ccattctcat aataaaaaag gtaatcctct tcttttcata
    21661 aaaaggttac ctctttttca atactattaa cttttaatgt tgaatttttt tacttttcta
    21721 tagagtgtag ctatacctat atttaatgcc tcagctactt ttttcatacc ttctgtatta
    21781 cttccatatt tctttatggc attttctata gcttccctct caaggtcatc tatagtctta
    21841 acttcttgtt tataaagttc atctagttta aaagatatta aatcagacat actccttaca
    21901 aaagcagtta actccttatc ttttgaaagt atcttttctt tttgttcttc attaaacgca
    21961 gctataccca agattccaag tatatgctct cccattttaa cgggagtaca tatatcagct
    22021 aactctttac aattttctct atttgcacat ttattacagt tctcttctat ttctttattt
    22081 ataacatagg atttcccatc ttttaaaaca agagagtaca ctgacttctc tgatattgtc
    22141 tctcctattt tacctctgaa tattcctgta cctgctatcc tagttaaatc ttttgtaact
    22201 aaagtaacat ctacatccaa gacattagaa atattctcgc aaatactttg aacgtaattc
    22261 gttatattat ttaaattcaa agtaatccct cctatttaga tttatatttt ttattactct
    22321 acataaatcc tattcttgag aactttaagc ttgcggttgt ggttgtgtct cattaggctt
    22381 attatcagtt ggtggtgttt ctggtttttg ttgattattt gggttttgat tgtttgtatt
    22441 ttgattattc ttattttcgt ctgtatttgg tttttcctct ggttttggtt ccatagtccc
    22501 aactaatata ataccttcct tcttaggata atatgaatta gctatttttt cagttttaat
    22561 ttttttacca tttgcatcat taaatgttct atatgttgat acagaatatg catttcttcc
    22621 acttttgtct actttttctt tacctttagg cattgtaggg tcattaactc ttttcattgt
    22681 agtttgtgaa acgccatcta attttgttga tattgttata ttttgtttat cttctgcact
    22741 tccatatata ttgcaaacaa tttgatttcc tgaaacgtaa ttttttatgt aaactggatg
    22801 ctttagatta tttttaaata agaaatctat tccactatct gcaacagttg catctcttcc
    22861 ttttggaaca taacttgatg gtatagtatg attttttaca ttaacaattt ctaaacctgc
    22921 gtatagcaca gaattgtata acgtagatga aacttgacaa actcctccac cataatcttc
    22981 ttccatctca ccttccatta ttacaggtgc acttttatat ccattttcct tacttctttt
    23041 ccctgtatgt ttattaaatg agaaagtttc tcctggcata agtaatacat tacttatatt
    23101 atctgttgct aattttatgt ttatacttct atttatttga gaagttttaa atgttgttga
    23161 atacgtacct aaatttgtat ctatattagc aagttgctct ttttttactt ttgctggagt
    23221 agcttttact actaactcat ttttatagtt acctttttta gtttgattat caaaattctc
    23281 catactctta gaaatatcca ttttaagacc atcagaatct ggtataacct tgactttttc
    23341 accacttata tcaagtgtag catcttttac atctacatct atttctttag ctatcttttc
    23401 catttctgct tttaatttat ttttatcata atttatcgca actactaagt tgcttttttt
    23461 gccaaaattt gctgaaatag tttttgatag attgccaaag aaagcactct ttctatttaa
    23521 attatatgcg ttttctactg ttttatccag gtcagtagat aaatttaaat ctttgctctt
    23581 tactttccag cttttatcat tgtaattaaa atcaacattc tctaatttgt attttttagc
    23641 taattcctgt tttgcttgtg atttagttaa ttttccaata tttactccat taacatatgt
    23701 gttttttgct attttctccc ctttaaattg catgcacatt atgcctataa aaattattac
    23761 tactaatgct acagctccaa tagctataac tagctttttg ttcacattac tcatcccata
    23821 cttctcctta caataaaatt atttatatat ccctattatt atattactac ataatgcgcc
    23881 ttaaaacccc aaaaactttt taattatata ttaatttaat attattaatt aatattcatt
    23941 tagtccattt tctgatatgg catatatttt ttcattgtaa atattaatag cataaacttc
    24001 tttgcctcta aataagcctt tatttactac agcataataa taaatatttt tatattttcc
    24061 aaacaattct tctaaactct ttttactttt tacatatcta tctgctttct ctatatctaa
    24121 tatctcaatc tttttatact tattttcttt ttcatcaaga gtattagtta acacaaactt
    24181 agctttatct tttgtaatac caaattgata acttccatct tctaatattc taaagtatcc
    24241 atcaccataa tctactttgt aatctttttt accatcttta tatgaatata aatctttagt
    24301 ttttgcactt accaaaactt catttattaa tttatcatac tcatatactt cagcataata
    24361 gtatttatta ttttttatca tttgtggaag tgaatttata gatagatttg ccttgtcttt
    24421 gccacttttt ttagctatta catttataat gtcatcagat gttaaagtat acaatgataa
    24481 attcttttta tatttttttt ctaaactctg taccttttca tcatctgaat aatcgtcttt
    24541 taaatactca atatattgta atgctctttc ataatctcca gaagtatttg cctcttcagc
    24601 tctacttata tagtaatcat acatttcttc aatacattgt tctttcccat tttgagccat
    24661 actgtaatac ttttcatctt cttttaatac tttattatac ttttcaatag cttcataata
    24721 cttatatgct ttttggtctt ttactgctga gtcataaaca tctctagact ctttgattgt
    24781 ttctatattc tgtttgtata catctaggtt actacccata ccatttaata ttgaaacagt
    24841 acttatgtag ttaatggcaa tatcataagt agtattttct tctttataca tttctctaac
    24901 tctatcagct tgagctaata agtcatccac atctatactt attttgttta attctttcac
    24961 ggtatttatt aatccaataa aactttcttg acttatgtct ccatctaaat atttatcacc
    25021 actatttaat agcaatttat ttattttttt agaaacagac ttattaaacc tttccatttt
    25081 tgaatcagaa aacttttttt ctatacttgt gtagtaatca acagctatag aatactgtct
    25141 tttctctata atctttaaca actcattagc ttcatttcct acactaaact cgttactact
    25201 taagaaaaat actattatca aagcaattac acctaatgtt gataatgaaa tcgcaactat
    25261 agatttcctt ttttcatcaa taaaatctac agccttctca aataaatctc taaaattcat
    25321 tatagttccc tctccattta ataatcttta tattttatgg taaactaaat ttcttattgg
    25381 ttattatatc ataattcttg aaaaaaaata aaaacacaag ttaaatcgtg tttttatttt
    25441 acctatcaat cattatttta tacataaata tttcctttac ataaattatg atatctttct
    25501 ttttatatcc ctagaatgac tcttttgttt tttattatta ctgacagttt tcgttcttgt
    25561 cttgtgtata gctttgctat caaatatttt tctagcattg cataaaacaa ttccaattgt
    25621 taaacaaact gtaagcacac ttcccatcaa aaagtaataa tccaatccta tatgtactcc
    25681 cataactgaa tttattaaca ctaatgcaaa agtcattgca aaacatatca tcatggagat
    25741 aactaaaatt cttagaattt ttttcaatcc actcacctcg tataatcact aaaattgaca
    25801 ctacccctta tccattacta taccaaatta gtaaaaaaat agcaattact attgtcattt
    25861 atattaggaa aatattaaat ctttttaata aatatctttt tttgacataa ggattactta
    25921 acttttaata aaatagtaac actaatatgt attaattaat agaataaaat aaatgataat
    25981 ttattgaggg gtgatttaca tgccaaattt gccaagttta gggtcaaagg ctcctgattt
    26041 taaagccaat acaacaaatg gtcctattag actctctgac tataagggta attggattgt
    26101 tttattttca catcctggtg attttacacc agtttgtact acagaatttt tatgttttgc
    26161 taaatattat gacgaattta aaaaaagaaa tacagaacta attggtctaa gtgttgatag
    26221 taacagttca catttagctt ggatgtataa tatttcttta cttacaggtg tagaaattcc
    26281 atttcctatt atagaagata gagatatgag aattgccaag ttatacggca tgatatcaaa
    26341 accaatgagt gatacatcaa ctgttcgctc tgtatttatt atagataata atcaaattct
    26401 aagaacgatt ctttattatc cactaactac aggaagaaat attccagaaa tacttagaat
    26461 agtagatgca cttcagacta gtgatagaga taatatagtt actcctgcaa actggtttcc
    26521 tggaatgcca gtgattttac cttatcctaa aaactataag gaattaaaaa atagagttaa
    26581 cagttgtaat aagaaatatt catgtatgga ctggtactta tgttttgtac cagataatta
    26641 taatgatgaa gaagtgagca agaaaattga taatacttgt agctggaaaa aagaacatac
    26701 taaaaacatt gaaaatgaat gtaactgtga acatgaacat catgactacc tgaacaaagc
    26761 tcttgactgt aaacaagaac acaagactga tattaaagat gattgcaatc atgagaaaaa
    26821 acatactaaa aatactaaca aagttcacaa ctccaaacaa gataagttta aagataagtc
    26881 ttgtgatgaa atgaatttta actatgataa agatgaatct tgtgacaaaa taaattctag
    26941 ctataacaaa gaagatagta gttatgaaga tttctataaa cataattata aaaactacga
    27001 ttatactagc gaaaaaaata ctaaaaaaat agctatgaaa actttaaaag attctaaaaa
    27061 attagttaga ccacaaataa cagacccata caatccaata gttgaaaatg caaactgtcc
    27121 agatataaat ccaattgtag cagaatatgt tcttggaaat ccaactaatg tagatgctca
    27181 actattagat gcagttatat ttgcttttgc tgagatagac cagtctggaa atttgtttat
    27241 tccttatcct agatttttaa atcaattact tgctcttaaa ggtgaaaaac ctagcttaaa
    27301 agtaattgta gctattggag gttggggagc tgaaggattc tctgatgcag cattaacacc
    27361 tacatctaga tataattttg caagacaggt caatcagatg ataaatgaat atgctttaga
    27421 tggaatagat atagactggg aatatcctgg aagtagtgca tctggaataa catcaagacc
    27481 tcaagataga gaaaacttta cactcttact aactgccata agagatgtta taggagatga
    27541 taaatggctt agtgtagctg gaacaggaga tagaggatat ataaattcaa gtgctgaaat
    27601 agataaaata gctcctataa tagattattt taatcttatg agttatgatt ttacagcagg
    27661 tgaaacaggc ccaaatggta gaaaacatca agcaaatctt tttgattcag acttatcttt
    27721 gccaggatat agtgttgatg caatggtaag aaatcttgag aatgctggaa tgccttctga
    27781 aaaaatcctt cttggtatac cattttatgg aagattaggt gctactataa caagaactta
    27841 tgatgagctt agaagggatt atataaataa aaatggatat gaatatagat ttgataatac
    27901 tgctcaagtt ccatatttag ttaaggatgg agattttgca atgtcatatg atgatgcttt
    27961 atcaatattc ttaaaaactc aatatgttct tagaaattgt ctaggtggtg tattctcatg
    28021 gacatcaact tatgaccaag caaatatact ggctagaacc atgtctattg gtataaatga
    28081 ccctgaagta ttaaaagaag aacttgaagg tatttatggg caattctaat agaatgtagg
    28141 aaaattttat agttatataa aaagcagatt ttattatatt aaataagttg tatctaatta
    28201 atactattat taattgttta taaattagat acttattttt tcataataca atctgctttt
    28261 ttaatcaaaa tttatttaat tataagttgt ttaattacaa gttgtttaat tacaagttgt
    28321 ttaattataa agtaggaatt tagatatact cttataccat gtaattatgt ataaatattt
    28381 ttttattata caccaatagc ttttttagct aatttatctg cttcctcatt atacttattt
    28441 ccagaatgag ctttaacctt tgtaaatttt acattaagct tattcttaat actgtcatag
    28501 aaatttttat atgctatagt tccttcttta tttgttttcc aaactccagt acaccacttt
    28561 tcaatccctt catagtcaaa gtataaaatc aagttttgaa cattattgtc aatacagtac
    28621 tgcattgcaa ttttagaagc ctctatctct ccagctacat ttctcatact tactaaagtt
    28681 ttctcttttc ctttttcact ataagttttt ataacttcat tattttttaa aatcacaaca
    28741 cccgaaccat acatttttac tgaatgttca taacttccat ctacatatgc ttctataaac
    28801 tccttatctt cttgaaaact caatttttct gacccatcaa tatattcttt agcttcttga
    28861 aaagtagaaa aactcttata ttcagctcct gagaatccat ttacttgttt tttgcactca
    28921 tcccatgtat tatatacacc tatattttta ccttttttca cagcataaaa cttttgtttt
    28981 gccaaatata tcactcccac tcttaatttt tatcttcttc tctcataaat atatctaaat
    29041 ttataagata gtttctatca aaatatttta ctttcatatc tttttttata atatcaatat
    29101 ggtacacttc tccttttaca gctctttgtc ttatattttc atttatatct ttttttataa
    29161 tatccttatc aacatcattg ttatccattt tagcatcaac attcaacgct tttatagtat
    29221 caaatataac agattttagt attaaacttc tatatttatt taaatgtcgc cttatataag
    29281 tataaaactc attgctatta acctttgaaa ttttacaatc gtgtaaatct ttctctaatc
    29341 tctttaacac acttatatta gttcctacat caaaaatcac aaaacatcca tagtcatatt
    29401 tgcttcttaa aattctcccc atagcttgct ttacctttat ggtcatttga ggataattta
    29461 tagtatagta gtctatacca tacttcttca ttatagtaaa atacaaaggg tcttttggat
    29521 ttagattcgg aagcttgtct aaagttacac aaaccaaacc atcccctgga atgtctacgc
    29581 cttcaaaaca tccttttgag ccaagtacta cacattttct atttaaatcg ttaaggtgtc
    29641 taatcccctt tttatcagca taaatttcta agttaaaact atgtaagtat tttttcaata
    29701 tttcataagt tttttcttgt ctatctttac tattaaaaag agctaatgta tgaccttctg
    29761 taatctttga tatattagat ataattttac tcatctcatt tggaaattca gaatttctgt
    29821 actcacaaat atcagaaaat ccaactacag agactctatt tttataatca aaaattggtt
    29881 ctataatctt ttccacattc ttaactctgt ctattcctaa tgtattttta aaataagaca
    29941 tactttcaga taaactcaaa gttgctgata aaaatattcc tttttctaat tgagataaaa
    30001 tattttcttc aaataaatct gctattttta atggcactac tcgaaattca aagtcattat
    30061 aattcttatc aatttcaact atccttgcat aatcatcctt ttcatcatac tctaaaaaga
    30121 tttcaaatat aatctttata tcctctaaat ctcttgtctt tgcctttcca aatttatata
    30181 tatctgcttc tttatctata ctatcatcat caatattcct ataaattatt attattattg
    30241 aaactaaatt ttttattatt ttctcacaac tcaactttat cttttcacta taggctctat
    30301 aacttatttc agtatctata ccatcctttt ttagttttcc cacaatttcg tctatttgca
    30361 aattcagttc ccatcttaaa ttataattac ttacattatt atattcatta caattaccaa
    30421 actttaatat tgaatctatc tcttcaataa tgagatttat acttctagca attttttgtt
    30481 tatcttctct tccaattttt aatacattat aaaatttatc aaaagccttt atttttctca
    30541 tatttctact atatttttta tatataaagc tactattttg aataaactcg taaggataaa
    30601 tttcttgtaa taaatacctt aaagactttg aatttataat gcttgaaaag aaatcatatc
    30661 ctttttcagt caaattatgt gcttcatcta ctattatatt ttctaaaggt ttttcatcct
    30721 tatatggcca tttagctaat agtgaatgat ttactactgt tatatgttct tcttttaatt
    30781 cttctattct gtttttatat aaacaatctt ttttgcattt tttaggtctg cacatatttg
    30841 ggtcacaact tacatttctt aagtgagtac ttatttcctt gaagttgtca aacactaaat
    30901 aatttatttc ttctatatct ccatacttgc caccttcaac taatctcttc aaaaatatta
    30961 aagataaaat ttctccttta gtagggtttt gagactcata atcatctata tatgcttcca
    31021 gtctatctat acaaatatag ttattttttc cctttatata tccgtaactt acttttccat
    31081 ttagacccaa agaatctaac acatttggaa tatctttatt tattaattgt atctgcaatt
    31141 cctttgtgtc agtagaaatt aataatcttt ttttattaat tctagcctct aatattgcag
    31201 gcaataaata tcctacactt ttacctatac cagttggtgc ctctatacat gcaatttttt
    31261 cttcatcttc gctatttcta aacaactctc ttattgtttt agtaagctca tattgaccag
    31321 gtctatattc atatgtaaat ccttctttat tctcccaaat agttttgtat tttaataatt
    31381 cttcataatt tttttcttct tcatttaaaa tttttaaggt ttctctttcc ttcttctttt
    31441 cttcttttga gtcaaatata ttatattctt tttttatatt tatattattt gataaatcat
    31501 aatttgcctc ttctaaaaat ttgctccatt cccatgttgg aagattaaat tttttaagat
    31561 atgaatttat tttaaaactc aatggctcca aagtagtttt ttcatagtta ttaaatttta
    31621 ctaaaaggca atttacaata tttattatat caatagcatc tgataaagct ctattttcca
    31681 ctttagaatt acaatttgtt aaag
//
LOCUS       DAEPKC010000038        31558 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.038, whole genome shotgun sequence.
ACCESSION   DAEPKC010000038 DAEPKC010000000
VERSION     DAEPKC010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 31558)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31558)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31558
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.038"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            50..931
                     /locus_tag="KR294_001822"
     CDS             50..931
                     /locus_tag="KR294_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HBH0239902.1"
                     /translation="MKKRLIIMILSVVLVLSSILTIFAYSNIKYNNNKLIYSNMIDKK
                     TQNSVKEILKENKINEKDIDTFIKAVNNYNKLQVKILQNNINISKSGYSSINAKQVPY
                     NLEKLQDNWVKKFPDYMDVNCRITAFRLFKDFINSNKKFTGDSIDLNVDLDTIMNNKD
                     AKFSIKDVEKFINFFSAIPAKDTDDTIKISEQIKNEWKKRKISFKNNKNISIINGFLR
                     YPETKNVFIGHTGICIKTKNGILFLEKYGVTSPYQVTKFKNKEDVKNYMFNRLKMSEG
                     EIELPDPIIMENDKLMK"
     gene            complement(1244..2023)
                     /gene="hisJ"
                     /locus_tag="KR294_001823"
     CDS             complement(1244..2023)
                     /gene="hisJ"
                     /locus_tag="KR294_001823"
                     /EC_number="3.1.3.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase HisJ"
                     /protein_id="HBH0239903.1"
                     /translation="MKDGHIHSPYCPHGSKDDFEKYVQRAMDVGITEMTFTEHFPYAN
                     GFRDPAPENDSCMSIEDLPKYFNDVKKLKEKYEGKIKINVGSEVDFIEGYEEGIKENL
                     NKYGKELEDSLLSVHIIKIDDDYYCVDYSVEEFQNLIDKLGSIEAVYNKYYETLIKAV
                     NSDLGIHKPKRIGHLNLVRKFNQVFPYDYKGNTILEELIKLIKEKGYELDYNVSGNRK
                     EYCKEPYIDGYLLELVKKYDIPLILGSDSHCAEEINKYDIV"
     gene            complement(2569..2919)
                     /locus_tag="KR294_001824"
     CDS             complement(2569..2919)
                     /locus_tag="KR294_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc transporter"
                     /protein_id="HBH0239904.1"
                     /translation="MIFDKEIVRYHHGHHDHDHCHEHTHGDICHEHPHDHAHDHDHEH
                     SHEESSESKDEKTLKILLVHWINHNETHEEGFREWVEKARAIGKEETAKSIEKAIEYM
                     EEANKMLLEAKKHM"
     gene            complement(2935..3351)
                     /locus_tag="KR294_001825"
     CDS             complement(2935..3351)
                     /locus_tag="KR294_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3842 family protein"
                     /protein_id="HBH0239905.1"
                     /translation="MIIAVIDGMGGGIGAQIVSSLREELPTYVEIYALGTNSIATSSM
                     MKAHANKGATGENAIVVSAKKANIIVAPISVIIPNSMMGEVTCNISEAIADSEALKIL
                     LPIMPENVELVGLEGKPLALLVKDSVNLIKKEFNIK"
     gene            complement(3370..3561)
                     /locus_tag="KR294_001826"
     CDS             complement(3370..3561)
                     /locus_tag="KR294_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CooT family nickel-binding protein"
                     /protein_id="HBH0239906.1"
                     /translation="MCESSAFICKSNNELEKVMENVVNIDPCDGKIYLTDLLGEQKII
                     DGIIKEIRLMDHKIIIQEN"
     gene            complement(3712..4527)
                     /locus_tag="KR294_001827"
     CDS             complement(3712..4527)
                     /locus_tag="KR294_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HBH0239907.1"
                     /translation="MNQWRVIHNKSYEGAMNMAIDEAIFTAYKKGHNKPTLRFYTWEP
                     ACLSIGYFQKLEDEIDLDKCRCMNIDYTRRITGGRAVLHDNELTYSIIIGEDNPLIDK
                     SINLSYRYISEGLVKGLNLSGIETDNLNRGERISRENLSAACFNAHASYEVTINNKKV
                     IGSAQSRKDGVLLQHGSIILDFDVEKLFKLIKTKTPELKERAMKFTAKKASGIENEIG
                     RKIDIDILQKNIVKGLAEQFNVEFVEGDLTDYEKQLVKELYEKYKNEEYNKKR"
     gene            complement(4574..5512)
                     /locus_tag="KR294_001828"
     CDS             complement(4574..5512)
                     /locus_tag="KR294_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBH0239908.1"
                     /translation="MIRLSVGTAIELGILNKKSDIPPTTAYIMIGEKCINKCSFCSQS
                     IESSTRKDKLSRVIWPEFSKEEILDALKAYKGKNIKRICIQSMASEEAHNSVLDFINY
                     ISGKIDMPISLSAKLENDEQIKKFFSVGVDKIGIAIDAANKELYEKIKGNNYDEKLKF
                     ITEMSKSYPNKISTHIIVGMGESHEDIYNLYTYLKENDVTISLFAFTPVRGTKMEKIN
                     QPSIESYRRVQLMSYMINKGYPKEYFKFKNGYLNSIKLDNDILKDINKGYPFEIRGCK
                     DCNRPYYNERPGSTIYNYSRPLNQSEIDLAIREINL"
     gene            complement(5509..6381)
                     /locus_tag="KR294_001829"
     CDS             complement(5509..6381)
                     /locus_tag="KR294_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBH0239909.1"
                     /translation="MNKNLSEKMEIAFDIKLKNFGNKIEFAYPNQTLALSTTSNQCSL
                     KCAHCNGHYLNNMVPIEEYEEKVQSRNITSFLLSGGCSYEGDVPINTHINTIKNLKEQ
                     GYRLNAHLGLMDKDSIVELCKYLDIVSFDLVFDDETIREVYKMKKSKEDYIEVYNTIQ
                     EHTEVAPHICIGLKGGQIKGEYEIIEYLQKNPPNKLTFIVLIPTKGTEYENVEPPELE
                     GVADILCEARINLPDTEINLGCMRPRGVYRKELDQLSIMCGVNRIVLPSRSAKNKAIE
                     MNMTINECKECCVL"
     gene            complement(6406..8334)
                     /locus_tag="KR294_001830"
     CDS             complement(6406..8334)
                     /locus_tag="KR294_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4445 domain-containing protein"
                     /protein_id="HBH0239910.1"
                     /translation="MIKVSFTPNNKEVYCNEGDILLEVARNADIFIDAPCNGNVSCGK
                     CKVKLLNGKVDTEKTRHITDDEWEQGYILACCTKVISDIEIEVPSKVSSSMHGMKIEG
                     SNKKEDREIFERAKKIIEEHNLQFKTNIKKKYIEMEEPNLDDNISDVDRLERYVRNNL
                     GYNEIDFRLDILRKMPTVFRKSDFKVTITYVQKQKKLTIINIEQGNKENSLYGVAIDI
                     GTTSVVVCLVDLYSKEVVDKASSGNAQIKYGADVINRIIYSTKKNGLETLHKAIVEET
                     INPLLKTIYERNGIDKEDVVTLVAAGNTTMTSLFLGVYTDFLRQEPYIPPFLKSPKLM
                     GENVGLFVNDSAYVYLAPSVASYVGGDITAGVLSAGIWSSEENVLFIDLGTNGEIVFG
                     NKDYMMSCACSAGPAFEGGGISCGMRASAGAIEKVIIDKETLEPTLKIIDECAPVGIC
                     GSGIIDLICQMITKGVIDRRGKIYRDLDNKRVRFNEHEIGEYVLAFKEEFDLENDIVV
                     NEVDIDNFIRAKGAIYSGAYTLVDSLGMDFSILDRVYIAGGIGNNLDIENSIIIGLLP
                     DIDREKFTYIGNSSLVGSYLALISKDAKNKLEEIGNQITYVELSVYPSYMDEFISACF
                     LPHTNIEQFPTAKKLLEE"
     gene            complement(8446..8823)
                     /gene="gcvH"
                     /locus_tag="KR294_001831"
     CDS             complement(8446..8823)
                     /gene="gcvH"
                     /locus_tag="KR294_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein GcvH"
                     /protein_id="HBH0239911.1"
                     /translation="MKLLPELKYSKDHEWVKVIDGDVVYIGITDYAQDQLGEILFVET
                     PEVEDTVTKGVDFGVVESSKVASDLISPVNGEVLEVNEKLEDEPECINEDPYENWILK
                     VKLADVAELDTLLSDKEYEAGLE"
     gene            complement(8910..11036)
                     /gene="cdhC"
                     /locus_tag="KR294_001832"
     CDS             complement(8910..11036)
                     /gene="cdhC"
                     /locus_tag="KR294_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CO dehydrogenase/CO-methylating acetyl-CoA
                     synthase complex subunit beta"
                     /protein_id="HBH0239912.1"
                     /translation="MNLYNIIFTGSEQALGAAQAMLAEAIEKNGKEHKVAFPDTAYSL
                     PCIYAATGQKMNTLGDLEGALEVVKSLINRTHLLEHAFNAGLATALAAEVIEALKYST
                     MDAPYSEPCAGHITDPIIRSLGVPLVTGDIPGVAVVLGECPDAESAAKVIKDYQSKGL
                     LTFLVGKVIDQAIEAGVKMGLELRVIPLGYDVTSVIHVVSVAVRAALIFGGLTPGDLN
                     GLLEYTANRVPAFVNAFGPLSELVVSAGAGAIALGFPVITDQTVLEVPMNLLTQKDYD
                     KIVATSLEARGIKIKVTEIPIPVSFAAAFEGERIRKSDMFAEFGGNRTEAWELVVKKE
                     ATEVEDHKIEIIGPNIDEVDADGVLRLPLAVIVKIAGKNMQEDFEPVLERRFHYFLNY
                     IEGVMHVGQRDMAWVRISKDAFDKGFRLEHIGEVLYAKMLDEFESVVDKCEITIITDA
                     EKVSELKGEAIAKYNARDERLASLVDESVDTFYSCNLCQSFAPAHVCVVTPERLGLCG
                     AVSWLDAKATKELDPTGPCQPIEKGECLDDRTGVWNSVNETVNQISQGAVESVTLYSI
                     LEDPMTSCGCFECICGIMPEANGFVVVNREFASVTPVGMTFGELASMTGGGVQTPGFM
                     GHGRHFISSKKFAYAEGGPERIVWMPKELKDYVADKLNATVKEMTGIENFCDMVCDET
                     IADDSEGVLAFLEEKGHPALAMESVM"
     gene            complement(11093..11899)
                     /locus_tag="KR294_001833"
     CDS             complement(11093..11899)
                     /locus_tag="KR294_001833"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HBH0239913.1"
                     /translation="MEKFMIIGERIHCISPSIRKALAERDPAPILKRAKEQLEAGAHY
                     IDFNIGPAERDGEEIMTWGIKLLQSEFNNVPIALDTANKKAIEAGLKVYDRTNAKPII
                     NSADAGSRFDLIDIAAEYEAMVIGLCAKEGIPRDNDERMAYCQEILEKGLMLGMEPTD
                     ILFDPLCLVIKGMQEKQVEVLEAIKMMTEMGLLTTGGLSNVSNGCPKHVRPVLDSAFL
                     AMAMANGFSSAIMNPCDPELMKTVKSCDIINGASLYADSFLELNEGGFAF"
     gene            complement(11949..13316)
                     /locus_tag="KR294_001834"
     CDS             complement(11949..13316)
                     /locus_tag="KR294_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA decarbonylase/synthase complex
                     subunit gamma"
                     /protein_id="HBH0239914.1"
                     /translation="MALKALDIFKLTPKKNCKDCGFPTCMAFSMKVASGAVEVGKCPH
                     MSDDAIAKLSEATAPLMKALKVGAGASEYELGGETVLFRHEKTLVSRNRYAVSFCTCM
                     SDEAVDAKIANMKKVDYVRIGEQMKVEMAVLEYCGDKDAYLKLIDKIKGSGLEVAYIL
                     ACDDAQVVKEAVEVLKDARPMVYGATKENYKDMIEVVKGASLPLGVKAGSLEELYETV
                     ELIQAAGYKELVLDVTGENIKDTYTNAIQVRRTALKEQDRTFGYPSIVFANRLSNSNP
                     MMEVALSSIFTIKYGSIIVIDDISYAKALPLFALRQNIYTDPQRPMRVEPKIYPINNP
                     DENSPVLVTVDFALTYFIVAGDIERSKVPVWLVIPDAGGYSVLTSWAAGKFGGNSISA
                     FIKESKVEEVTNCKDLIIPGKVAVLKGDIEDNLPGWNVVIGPEESMELPKFLKGYQEK
                     ACQTN"
     gene            complement(13347..14291)
                     /locus_tag="KR294_001835"
     CDS             complement(13347..14291)
                     /locus_tag="KR294_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA decarbonylase/synthase complex
                     subunit delta"
                     /protein_id="HBH0239915.1"
                     /translation="MAFKMSTQKYSGKISEVEVGIGEKAIKLGGENVLPFYSFDGEVG
                     NSPKIGIQISDVYPESWTDSYKELYKDVANCPVEWAKYVEANTQADFICLKFDGSDPN
                     GLDKSVDECADVAKAVIEAIKLPLVVAGSGNHEKDGKLFEKLAQTLDGHNCLFMSAVE
                     DNYKGVGASAGMAYAHKVGAESSVDINLAKQLNVLLTQLGVKGENIVMNVGCSAVGYG
                     YEYVASTMDRIRLAAFGQNDKTLQMPIITPVAFEVGHVKEAIAPIEDEPDWGCPEERT
                     IAMEVSTAASVLVGGSNAVILRHPKSIETIKELVNALA"
     gene            complement(14311..15081)
                     /locus_tag="KR294_001836"
     CDS             complement(14311..15081)
                     /locus_tag="KR294_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBH0239916.1"
                     /translation="MGYNIAVAGKGGTGKTSLTGLLIDYLVKDKKGPVLVVDADANAN
                     INEVLGIEVEATIGEIREEVNQREKLGNAFPGGMTKAQYLQFRLNSIIEEGEGYDLLV
                     MGRSEGEGCYCFVNGILREQVNKISGHYKYLVMDNEAGMEHLSRKVTRHVDTLLLVSD
                     CSRRSIQAVARIRDLAEELKLSVGRILLIVNKVPNGVMNDGVKEEIEKHNLELIGVVP
                     MDELIYEYDSTGIPLVNLPEDSKSKVAMKEIFAKLELK"
     gene            complement(15137..16522)
                     /gene="lpdA"
                     /locus_tag="KR294_001837"
     CDS             complement(15137..16522)
                     /gene="lpdA"
                     /locus_tag="KR294_001837"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HBH0239917.1"
                     /translation="MKIVVVGGGPGGYVAAIKASMLGADVTVVEKRRVGGTCLNAGCI
                     PTKALLASSGVLNTVKEAKDFGIEIDGTVKPNFTAIMERKNKVVNQLISGIEFLFEKR
                     GVNLVNGFGKLIDKNTIEVTKDDGTVETIKADKIILANGSVPVVPRMFPYDGKVVITS
                     DEVLGLEEIPESMLIVGGGVIGCEIGQFFRALGTEVTIVEMVDQILLNEDKDVAKQLL
                     RQFKKDKIKVITGIGVQTCEVVDGKAVATLSNGKVIEAQYALVCVGRRPNLDNSGVED
                     IGIEMERGKVVVNEHLETNVEGIYAIGDIIDTPFLAHVASKEGIVAVENALGKTKVVD
                     YRAIPRCVYTEPEVAGVGKTEKQLEAEGVEYNVGQFDFRGLGKAQAIGHFQGFVKVIA
                     DKETDKIIGAAVVGPHATDLLTELSLAVHLGLTVEQVGDAIHPHPSLSEGLMEALHDV
                     HGECVHSVPKL"
     gene            complement(16566..17447)
                     /locus_tag="KR294_001838"
     CDS             complement(16566..17447)
                     /locus_tag="KR294_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase"
                     /protein_id="HBH0239918.1"
                     /translation="MSLLRETLESGKFAVTTEMAPPKGTDLSHLIECAKPLVGRVHAA
                     NVTDFQSAVMRATSLATCKLLKDAGLEPVIQITGRDRNRIAIQGEMLSAGVFGINNLL
                     ALTGDHTSVGDHPQAKGVFDLDSVGILQTAETLMAGTDMAGNKLKGSPDFYLGASVTP
                     EYSPIEVQLLKMKKKIKAGAKFFQTQALYDINTMRKFRELTRDMDCKVLAGIVPLKSP
                     GMAKFMTANVPGIFVPDEQIERLRAAGKENWVSEGIKMAGELIKQLKEEDLCDGVHIM
                     AIGAEENIPAILDAAGL"
     gene            complement(17483..18157)
                     /locus_tag="KR294_001839"
     CDS             complement(17483..18157)
                     /locus_tag="KR294_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase C-terminal
                     domain-containing protein"
                     /protein_id="HBH0239919.1"
                     /translation="MIISENKPLEEVLGYLKDFDKLVLVGCNQCAATCKSGGEEEVLK
                     MKETLEGEGKKILGYVMLDPACNLLKSKKDLKALKEETKEADAVLSLACGDGTQTIVK
                     NLKDKPVYPANNTLFIGEVQRVGEYEEACKACGDCELGWTGGICPVTMCAKGLMNGAC
                     GGAKNGKCEVNSENDCAWIKIYERLEAIGQLDNLAEIRPPKDYSKQNNPRSLSAKKKK
                     EAAANS"
     gene            complement(18194..19066)
                     /locus_tag="KR294_001840"
     CDS             complement(18194..19066)
                     /locus_tag="KR294_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 5,10-methylene-tetrahydrofolate
                     dehydrogenase/5,10-methylene-tetrahydrofolate
                     cyclohydrolase"
                     /protein_id="HBH0239920.1"
                     /translation="MEGMSTKGQIIKGKPVADKISEELIKEVDLLIKEGINPKLTIVR
                     VGARSDDLSYERGALKRCQNIGITTEVLELAEDITQEEYIDVLKRVNDDKNVNGILCF
                     RPLPKHLNEEVIKYVIAPEKDVDCFSPINSAKVMEGDKSGFPPCTPTAVVEILKHYNV
                     DLKGSKVTVLGRSMVVGKPVSMLLLSEHATVTICHSKTKNLSGVAAEADVLIAAIGRA
                     KMVDESFVKDGAVVIDVGINVDEEGNLCGDVDTNAVLDKVSMITPVPAGVGSVTTSIL
                     AKHVVKACKLQNNK"
     gene            complement(19158..19790)
                     /locus_tag="KR294_001841"
     CDS             complement(19158..19790)
                     /locus_tag="KR294_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclodeaminase/cyclohydrolase family protein"
                     /protein_id="HBH0239921.1"
                     /translation="MKIADKTCVDFVEVLSSKEAVPGGGGAAALVGAIGMALGSMVCN
                     LTIGKKKYAEYEESVKEILSKAGKLEKDLLKMIDDDAECFLPLSKAYGLPKETEEEKR
                     IKAETMEKALKVACEVPLNIVRVCYEAIKLHEDLVDKGSRLAISDVGVGVQCLRAAIL
                     GGQLNVVININSIQDKEYVNKVKTEVDKLVEDGVKICDEVYAKVEKALGK"
     gene            complement(19895..21571)
                     /locus_tag="KR294_001842"
     CDS             complement(19895..21571)
                     /locus_tag="KR294_001842"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014355320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HBH0239922.1"
                     /translation="MGFKSDIEIAQEAKPQDIREVAKKLGLGEDDVELYGKYKAKVDY
                     NLLKRETGKKAKLILTTAINPTPAGEGKTTTTIGVADAFAKLDKNVLVALREPSLGPV
                     FGVKGGAAGGGYAQVVPMEDINLHFTGDFHAIGAANNLLAAMLDNHIHQGNALRIDPK
                     KITWRRCVDMNDRQLRNIVDGMGKKGDGAVRQDGFDITVASEIMAAFCLASDISDLKE
                     RLGNIIVGYSYEGEPVTARQLKANGAMAALLKDALKPNLVQTLEGTPSFVHGGPFANI
                     AHGCNSVIATRMAMHFADYVITEAGFGADLGAEKFLDIKCRMANLKPDAVIIVATVRA
                     LKYNGGVAKADLNNENLEALEKGLPNLLKHVENITQVYGLPAVVAINRFPLDTEAELK
                     LVEDKCKELGVNVALSEVWAKGGEGGIAVAKEVLRLLDEEENNFRFCYEDDLSIKDKI
                     NAIATKIYGADGVDYTPEADKEIANLEKLGFTKVPVCMAKTQYSLTDDQTKLGRPTGF
                     RITVRQATISAGAGFIVALTGEIMKMPGLPKVPAAEKIDVDENGVIAGLF"
     gene            complement(21820..22599)
                     /locus_tag="KR294_001843"
     CDS             complement(21820..22599)
                     /locus_tag="KR294_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBH0239923.1"
                     /translation="MKIAITGKGGVGKTTFSSMLSRMFAEDGYRVVAVDADPDANLAL
                     ALGFPKEVYESIVPISEMKKLVSDRTAASVGSFGKMFKMNPKVDDIPENFCKEYNGVR
                     LLTLGTVDSGGTGCVCPEHVLLKRLCSHLILQNKDVVVMDMEAGIEHLGRGTAQGVDA
                     FIVVVEPGERSLQTYRKVKKLGHDIGVNKVFVVGNKIRNKEDEEFIIQNLEDGESLGF
                     IYYNQDVIDSDRANQSPYDSSETTKEQIKAIKDKLMSLKDK"
     gene            complement(22909..24828)
                     /gene="cooS"
                     /locus_tag="KR294_001844"
     CDS             complement(22909..24828)
                     /gene="cooS"
                     /locus_tag="KR294_001844"
                     /EC_number="1.2.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic carbon-monoxide dehydrogenase
                     catalytic subunit"
                     /protein_id="HBH0239924.1"
                     /translation="MDEKMLTIDLNSQKMIAKAREEGVETMYDRKEGFKAQCGFGLQG
                     VCCRICGMGPCRISPKTPRGLCGADEHTIVGRNFARMVAGGTAAHSDHARDIAHTLAL
                     ADPNGNYKIRDEAKLITLAKEWDVETEGRDIYDVAHEVAEIALMEFGKPFGTLRFIKN
                     APEPRQKIWKEYAIEPRAIDREIATIMHSTHIGCTGDIDSLIHMSLRTSMADGWGGSM
                     IGTRLSDILFGTPVPRRTEANLAVLEENKVNIILHGHEPALSEMIVLASEEPDLVALA
                     KEVGADGINLAGMCCTGNEITMRHGVKIAGDFHQQELAIITGAVEAVIVDVQCIFPAL
                     ARVADCYHTKFVTTSPKAKITGSTYIEFREEQALDDAKAIVKEAILNFKNRDKSKVLI
                     PELKSGATVGYSVEAVVNQLDRVVNSHIDPAGTVKPLTDCLKAGVLRGAAGVVGCNNA
                     KGVSNEAHVTIMKELIKNDIIVVTTGCGASAAAKFGLMESDAAEKYAGKGLATVCKLV
                     GIPPVLHMGSCVDISRILDLVGAAANYLDMDMCDLPVVGIAPEWMSEKAVAIGCYVVA
                     SGIDTYLGIMPPIAGSSRAVDILTSELKDKVGATFTVNTNPKELAATIIEDIEKKRVH
                     FEALVEEKMAEKAEA"
     gene            complement(25435..26346)
                     /locus_tag="KR294_001845"
     CDS             complement(25435..26346)
                     /locus_tag="KR294_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional enoyl-CoA hydratase/phosphate
                     acetyltransferase"
                     /protein_id="HBH0239925.1"
                     /translation="MIKKLDDILEQLKGGEKIVLSVAAAHDKEVLMAIKDAVERNIIT
                     PILVGNEGKIREISKEIGFDLSGIKIVDKDDIKECAEIAVKLVSSKEADFVMKGLLDT
                     SVILKEVLNKDYGLRTDSLLSHVMVYELEKYHKLLITTDGGMNIAPDYEQKAKILKNS
                     IKAAKALGMETVKVACLAAKEKVNPKMQATVDADMLAKACKEGEFGENVIVEGPLAFD
                     LAVSKEASEIKGFKSEVSGDVDIILVPTIEVGNGIGKAFTYMADSKSAGIIMGAKAPI
                     VLVSRADSHESKLYSIAYGAIVAKNMK"
     gene            complement(26462..27040)
                     /locus_tag="KR294_001846"
     CDS             complement(26462..27040)
                     /locus_tag="KR294_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HBH0239926.1"
                     /translation="MNINEFLTHINQRKPVSSKSEIHEFMVKLSNEAMKITSKLNSSY
                     HEPEEVRSLFSELIGKKVDESFFMFPPFYTDCGKNITIGKNVFINSSCHFQDQGGIEI
                     GDNTQIGHNVVLATLNHGIAPEKRGTTYPSPITIGKNVWIGANVTVVPGVTIGDNAII
                     AAGAVVTKNVAENTIVGGVPAKLLRAIDEIPE"
     gene            27266..28189
                     /locus_tag="KR294_001847"
     CDS             27266..28189
                     /locus_tag="KR294_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBH0239927.1"
                     /translation="MEIRVLRYFLAIAREESISGAATFLHITQPTLSRQIMELEEELG
                     VKLLVRGNRKITLTNEGRLLHKRAEEIISLVDKVELEFDNPNEIISGDIYIGSGETEA
                     MRLIARTAHHFHQKYPNVRYHLFSGNADDVTEKLDKGLLDFGILIEPANIQKYDYAQI
                     PATDVWGLLMRKDSALASQSTINPKDLCNIPLIISRQTLVDKAISKWLQGSNEKLNII
                     ATYNLVYNASLLVEEGLGYALCLDRLVNTTENSNLCFRPLSPPLEAKLNIIWKKHQIF
                     SKAAEKFLLQIQKDFSSIMLDTSKLDTPKEK"
     gene            complement(28361..29503)
                     /locus_tag="KR294_001848"
     CDS             complement(28361..29503)
                     /locus_tag="KR294_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBH0239928.1"
                     /translation="MDFKIEKYLLKKAEELAFITIKHGGEFKLKSYEVPKGGLDVPIK
                     NEVLVKGIKEKTAQDKLNSMSIADAMIYIIGIDSKFKNNAEYEKFLNALSKDIDLDLK
                     SYMGYMSRKYFEIGEHTDSLIYIKAFITMYPDDLDAMYNYAIVCQEIAKQYQKDMDDK
                     AMNAFLLEAMAKLEKVIDVDENFALGYYHLGYHYYNQGQYLKTKLTWEEALRLGLDAD
                     LVAEVQENLGKMDFKVQYEEGYTLVFQGKFKEGLEKLLPLEEEHMDWWNLLFMIALGY
                     KGMGEIEQAKMYLEKILIIKPNQVDTIVELGLCEAYKNNLDKAIEYFEQAAKIKEDPE
                     ILCNLGMAYLNNGDIDDATYYIERAYELNPQDEITIACLRELGINK"
     gene            complement(29521..31275)
                     /locus_tag="KR294_001849"
     CDS             complement(29521..31275)
                     /locus_tag="KR294_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="B12-binding domain-containing radical SAM
                     protein"
                     /protein_id="HBH0239929.1"
                     /translation="MKILLTTLNSKFIHTNLAIRYLKEFVRDLIEVNMKEYTINNDLD
                     YILKDIYKNEYDIILFSTYIWNVGDIVKLCDNLKKIRPNTKIALGGPEVSYDSYEAMK
                     KYDFVDYILYGEGELIFRDLVLHLQGKMEINDVNGLVYRQGNEIIVNKPMELLQDLDE
                     IPSPYENLNPKEYENRIVYYESSRGCPFNCQYCLSSTIPGLRYFSLDRIKSDLKALID
                     ARVSQIKFIDRTFNANRKVAMEIMDFLMKNDNGYTTYHFEVTAYLIDDKMLEFLADCK
                     EGLFQFEIGVQSTNEKTLDAVGRRDDFKKLSHVVQTVASYRNIHQHLDLIAGLPYEDY
                     KSFENSFNDVFNLGIEHLQLGFLKMIKGTGMRKVADEHGFKYKDYAPYEFLYNNYISY
                     EETLKLKDIEDILERYYNSKNFVLSMRYIIGRFYKKSPFKFFEVFAKYFDENGYFDLA
                     QGKNQLYKILMDFYNEKINIDNDVFNDILKYDYISLGKTSNIPQFFNKLDVDDFKNRC
                     HVFLQDNDNLSTYLPSFVDKPAKHIIKYVHFEPFRFNVVDLKNDINTEIREVENVVLF
                     EYDDKKIFEKSKTHKVEI"
     gene            31411..>31558
                     /locus_tag="KR294_001850"
     CDS             31411..>31558
                     /locus_tag="KR294_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239930.1"
                     /translation="MELIEKVSINSLSKRDLLLIIKSLEYTNENTQISDFIDLRNNIV
                     KELCF"
BASE COUNT         9632 a         6233 c         3573 g        12120 t
ORIGIN      
        1 atatactata aatatgtcga cacaataaat ttaaaaagga gaattaaata tgaaaaaaag
       61 attaataata atgatattgt ctgttgtctt agtactatca agtatactta cgatatttgc
      121 atattcaaat attaaatata ataataataa attgatatat tctaatatga tagataaaaa
      181 aactcaaaat agtgtaaagg aaatcctaaa agaaaataaa attaatgaaa aagacataga
      241 tacatttatt aaagcagtca acaattataa taaattgcaa gttaaaatac ttcaaaataa
      301 tataaatata tctaaatctg gatattcttc aatcaatgca aaacaagttc catataacct
      361 agaaaaattg caagataatt gggtgaaaaa attccctgat tatatggatg taaattgtag
      421 aataactgct tttagacttt ttaaagattt tataaattca aataagaaat ttactggaga
      481 ctctattgat ttgaatgtcg acttggacac tataatgaat aataaagatg ctaaatttag
      541 catcaaagat gtagaaaaat ttatcaactt cttttctgca ataccagcta aagatacaga
      601 tgatacaatc aaaatttcag aacaaataaa aaatgaatgg aaaaaaagaa aaatatcttt
      661 taaaaataat aaaaatatat ctattataaa tggatttctt cgttatccag aaactaaaaa
      721 cgtatttata ggtcatacag gcatatgtat taaaactaaa aatggcattc tatttttaga
      781 aaaatacggt gttacatcac cttatcaagt tactaaattt aaaaataaag aagatgtaaa
      841 aaattatatg tttaatagat tgaagatgtc agaaggtgaa attgaattac ctgaccctat
      901 aataatggaa aacgataaac ttatgaaata ataactttaa acgcaaaata atatttataa
      961 ttactaagtc aatataatag agaaggtcta tagatttgtg taaatacaag cttatctaca
     1021 atcttatata agaatattta tataaataag atagattaat tctaagtcct attattctat
     1081 tgaattttat tattatttta tttagattct attgttattt tacttagaac ttattattat
     1141 tttgtttaag ttctattact attttcaatc atataaattt acaaaagact gtacataaat
     1201 ttattttata caaacttatc tacagtcttt tgtgtgaata tatctaaaca atatcgtatt
     1261 tatttatttc ctctgcacag tgagaatcag aacctaaaat taatggaata tcgtattttt
     1321 ttaccaactc taataagtat ccatctatat aaggctcttt gcagtactct tttctatttc
     1381 cagaaacatt ataatcaagt tcataacctt tttctttaat taactttatt aactcttcaa
     1441 gaattgtatt tcctttataa tcgtatggaa atacctgatt aaactttcta actaaattta
     1501 aatgacctat tctttttggt ttatgtatac ctaaatctga atttacagct tttatcaatg
     1561 tttcataata cttattataa acagcttcaa tacttcctaa tttgtcgatt aaattttgaa
     1621 actcctctac actgtaatct acacaataat aatcatcatc aatcttaatt atatgtactg
     1681 ataaaagaga atcctctaat tcctttccat atttatttaa attctccttt atcccttctt
     1741 cgtatccttc tataaaatcc acttccgacc caacatttat cttgatttta ccctcatact
     1801 tttctttcaa cttcttgaca tcattaaaat actttggtaa atcttcaata ctcatacaac
     1861 tatcattttc aggagcaggg tctctaaatc catttgcata cggaaaatgt tctgtaaatg
     1921 tcatttctgt tattccaaca tccattgctc tttgtacata tttttcaaaa tcatccttac
     1981 ttccatgagg acaataaggt gaatgtatat gaccatcttt cataaataat tcactccttt
     2041 tttaaagaaa aaatctaata taaatgcata aatcttttaa cttcaaaata atatttttaa
     2101 tcatgctaat ttttattata tctaatatta gagtaatttt aaactgcctt ttaagtatct
     2161 tatcattagt actattttca acttaacatt aatattattt tttaacttaa cattaatact
     2221 atctttaaat agtaatactc aatatataat tacttaaaat aaaataactc aaattgcttg
     2281 atgaggcttt tgcagtattt aaagaatata taattattta acattaaata atccaatctt
     2341 gtaataaaat ttactcatta aagtatatta cagaaaatac ctcaaaataa actttttagt
     2401 tcatgatata ctcttttttg catgaaatta gatatatttt tatcatttca acaatgaaag
     2461 ggaggcttat atccatcttt agacaacccc ttagataaaa tttttaataa ttaaacatca
     2521 caaaatataa aaatcgctta tatcaaacgt ataagcgatt aattatattt acatatgttt
     2581 tttagcctct aacaacattt tattagcttc ttccatatac tctatagcct tttcaatact
     2641 ctttgctgtt tcttcttttc caatagctct agccttttca acccactctc taaatccttc
     2701 ttcatgagtt tcattgtgat ttatccaatg tactaaaagt atttttaaag ttttttcatc
     2761 cttagactct gatgattcct catgactatg ttcgtggtcg tggtcgtgag catggtcatg
     2821 tggatgttca tgacatatat ctccatgagt atgttcgtgg cagtggtcat ggtcatgatg
     2881 tccatgatga tatcttacaa tctctttatc aaaaatcatt agttattccc cctgttattt
     2941 tatattaaac tcttttttta taaggtttac agaatctttt acaagtagtg ctaatggttt
     3001 accttctaat ccaactaact ccacattttc tggcataata ggtaaaagta tcttaagtgc
     3061 ctcactgtct gcaatagctt cacttatatt acaagtaact tctcccatca tagaattagg
     3121 tattattaca gaaataggtg caactattat atttgctttt ttagctgata ctactatagc
     3181 attttcccct gtagctcctt tattagcatg agctttcatc atagaactag ttgctataga
     3241 attagtccct agtgcataaa tttctacata tgtaggtaac tcttctctca aagaagaaac
     3301 tatctgggct ccaatacctc cacccattcc atctatcact gctattatca tatgaaattc
     3361 ccctattaat taattttctt gtattattat cttatggtcc atcaatctta tttctttaat
     3421 tatcccatct attatctttt gctctcctaa taaatccgtt aaataaatct ttccatcaca
     3481 agggtctata ttaaccacat tttccataac cttttctaac tcattattac ttttacaaat
     3541 gaaagctgat gattcacaca tataaatctc ctcctaatat gatttttatt aaaaatcaaa
     3601 aaaagattcc cttaggtatt tcaatacacc aaagaaacct tcatgatttc agtttttgta
     3661 tattattata ccttaagtat atcactttaa tttatgtaaa gtcaattaaa gttaacgctt
     3721 tttattatac tcttcattct tgtatttttc atatagttct ttaactaatt gcttctcata
     3781 atcagtcaaa tcgccctcca caaactcaac attaaattgt tcagctaatc cctttactat
     3841 gtttttctgt agaatatcta tgtctatttt tctgccaatt tcattttcta ttccacttgc
     3901 ttttttagct gtaaatttca tagctctttc tttcaattct ggtgtcttag tttttattaa
     3961 tttaaacaat ttttctacat caaaatccag tattattgaa ccatgttgta ataaaacacc
     4021 atcttttctg ctttgagcac ttccaattac cttcttatta ttaatagtaa cttcatatga
     4081 tgcatgtgca ttaaaacatg cagctgataa attttcccta cttattctct cgcctctatt
     4141 taaattatct gtttctatac cacttagatt caacccttta actagacctt cacttatata
     4201 tctataagat aggttgatgc tcttatcgat taaaggatta tcttctccta taattatact
     4261 ataagttagc tcattatcat gtaatacagc tcttccacct gtaattcttc tagtatagtc
     4321 tatattcata catctacact tatctaaatc tatctcatct tccaatttct gaaaatatcc
     4381 tatactcaaa caagctggtt cccatgtata aaatctaaga gttggcttat tatgtccctt
     4441 cttatatgca gtaaatatag cttcgtcaat tgccatattc attgctcctt catatgattt
     4501 attatgtata actctccact gattcatgat tattacgccc ccatttttag tataaatata
     4561 tcctagaaat cctctataga tttatttctc ttattgctaa atctatctca ctttgattta
     4621 aaggtcttga atagttgtat atagtacttc ctggtctttc attatagtat ggtctattac
     4681 aatccttaca acctcttatt tcaaaaggat agcctttgtt tatgtctttt aaaatatcat
     4741 tgtcaagctt tatactattt aagtatccat ttttaaactt aaaatactct tttggataac
     4801 ctttatttat catataagac attaactgta cccttctata actttctatg cttggttgat
     4861 ttatcttttc cattttagtt cctctaactg gagtaaatgc aaataaacta atcgttacat
     4921 cattttcctt taaataagta tataaattgt atatatcttc atgactttca cccataccaa
     4981 ctattatatg tgtacttatt ttattgggat atgattttga catttcagtt ataaatttta
     5041 acttttcatc atagttattt ccttttattt tttcatatag ttctttattt gctgcatcta
     5101 ttgctattcc tattttatca actcctactg aaaaaaactt ctttatctgt tcatcatttt
     5161 ctaattttgc agatagtgaa attggcatgt ctatcttacc acttatatag tttataaagt
     5221 ctaaaacaga gttatgtgct tcttcacttg ccattgattg aatacatatt ctctttatat
     5281 tttttccttt ataagctttt aaagcatcta atatttcttc ttttgaaaac tctggccaaa
     5341 ttactcttga taatttatct tttctagtac tactttctat tgattgagaa caaaaactgc
     5401 atttatttat gcatttttct ccaatcatta tatatgctgt ggtaggaggt atatcgcttt
     5461 ttttgtttaa tatcccaagt tctattgctg tcccaactga tagtctaatc ataaaacgca
     5521 acactcctta cactcattta ttgtcatatt catttctata gccttattct ttgcagacct
     5581 tgatggtaat actattctat tgactccaca cattatagat aattggtcta gctcttttct
     5641 atacactcct cttggtctca tacaacctag attaatttca gtatctggta aattaattct
     5701 agcttcacat aaaatatctg ctaccccttc taactcagga ggttctacat tttcatactc
     5761 agtccctttt gttggaataa ggactataaa tgtaagctta ttaggaggat ttttttgtag
     5821 gtattctata atttcatatt caccctttat ttgtcctcct tttaaaccaa tacatatatg
     5881 tggtgctact tctgtatgtt cttgtattgt attatagact tcaatataat cttctttact
     5941 ctttttcatc ttataaactt ctcttattgt ctcatcatca aacactaaat caaaagaaac
     6001 tatatctaaa tacttacaca actctacaat gctatcttta tccataagac ctaaatgagc
     6061 attcaatcta tatccttgct cttttaagtt tttaatggta ttaatatgag tatttatagg
     6121 gacatctccc tcataactac aaccgccact caatagaaag ctagttatat tccttgattg
     6181 tactttttcc tcatattctt ctattggcac catattgttt aagtagtgac cgttgcaatg
     6241 ggcacatttc aaactacatt gattgcttgt agtactaaga gctagtgtct ggttaggata
     6301 agcaaactct attttatttc caaaattctt taatttaata tcaaatgcta tttccatttt
     6361 ttcagataga ttcttattca tagtttattc cttcttaagt acattttact cttctagtaa
     6421 tttctttgct gttgggaact gctctatatt cgtatgtggt aagaaacatg cagaaataaa
     6481 ttcatccata taacttggat atacactaag ttcaacataa gttatttgat tacctatttc
     6541 ttcaagttta ttttttgcat ctttacttat aagagctaag taagaaccaa caagtgaact
     6601 attccctata taagtaaatt tttctctatc aatatcagga agtaacccta taattattga
     6661 gttttctatg tctaggttgt ttcctatacc acctgctata taaaccctat ctaatatact
     6721 aaaatccata cctaaactat ctacaagagt gtatgcgcct gaatatatag ctcctttagc
     6781 tctgatgaaa ttatctatat caacttcatt gactactata tcattttcta aatcaaattc
     6841 ttctttaaat gctaatacat actctcctat ctcatgctca ttaaatctaa ctctcttatt
     6901 atctaaatcc ctgtatattt tacctcttct atctattacc cctttagtaa tcatttgaca
     6961 gattaaatca attataccag aaccacatat accaactggt gcacattcat caataatctt
     7021 taatgttggc tctaaagttt ctttatcaat aattactttc tctattgctc ctgctgatgc
     7081 tctcattcca cagcttatcc ctccaccttc aaaagcaggt cctgctgaac atgcacagct
     7141 catcatataa tctttatttc caaatacaat ctctccatta gttcctaaat ctataaataa
     7201 aacattttct tcacttgacc atatccctgc tgataataca cctgctgtta tatctcctcc
     7261 tacataactt gcaacagatg gagctaagta cacatatgca ctgtcattta caaaaagacc
     7321 aacattttca cccataagtt ttggagattt taaaaatggt ggtatgtaag gttcttgtct
     7381 taagaagtct gtatacacac ccaagaataa acttgtcata gttgtattcc cagcagccac
     7441 taatgtaact acatcttcct tatctattcc atttctttca tatattgttt ttaatagtgg
     7501 atttatagtt tcctcaacta tagctttatg aagtgtctct aatccatttt tcttagttga
     7561 atatataatt ctatttataa catctgctcc atattttatc tgtgcatttc cagaagatgc
     7621 tttatctact acctcttttg agtataggtc tactaaacaa acaactactg aagttgtacc
     7681 aatatctatt gcaactccgt ataaggaatt ttctttattt ccttgttcta tatttatgat
     7741 tgtaagtttc ttttgttttt gaacatatgt tattgtaacc ttaaaatcac tctttctaaa
     7801 tacagttggc atttttctaa gtatatccaa tctaaaatct atttcattat atcctaggtt
     7861 atttctaaca tatctttcca atctatctac atcacttata ttatcatcta aatttggttc
     7921 ttccatttct atgtatttct tttttatatt tgttttaaat tgaaggttat gttcttcaat
     7981 tattttttta gctctttcaa aaatttccct atcctctttt ttattactac cttctatctt
     8041 cataccatgc atagaagatg atactttaga aggaacttca atttctatat ctgatattac
     8101 ctttgtacaa caagctagta tataaccttg ctcccactca tcatctgtta tatgtcttgt
     8161 tttttctgta tcaacttttc cattcaataa ttttacttta cacttcccac aagacacgtt
     8221 tccattacaa ggagcatcta tgaatatatc tgcatttctt gcaacctcta gtaatatatc
     8281 cccctcatta caataaacct ctttattgtt tggtgtaaaa cttactttta tcatgttatc
     8341 cctcccaatt tgttctatat atgataaaag gaaagtatag ctaaatttgc gtgcactcaa
     8401 attttactat actttcccca attataataa tatcttaatc tttaattatt ctaatccagc
     8461 ctcgtattct ttatcactta ataacgtatc aagttcagcc acatcagcta gttttacttt
     8521 taatatccag ttttcatatg ggtcttcatt tatacattct ggctcatctt ctaatttttc
     8581 attaacttcc aatacctcac cattaacagg agatattaaa tcagaagcta ctttagaaga
     8641 ctcaactact ccaaaatcta ctcccttagt tacagtatct tctacttctg gtgtttcaac
     8701 aaacaatatt tctcctaatt gatcttgagc atagtctgtt atacctatat atacaacatc
     8761 tccatcaatt acttttaccc actcatgatc tttagagtat tttaattctg gtaataattt
     8821 catttcgata gacccccaat attatattat tgattaaatt acttaaatca tattaatatt
     8881 atatcatatt attttaaatt ttccatcaat tacattacac tttccatagc taatgctgga
     8941 tgaccttttt cttctaagaa agctaatact ccttcagaat cgtcagctat agtttcatca
     9001 caaaccatat cacagaagtt ttctattcca gtcatttctt taactgtagc atttaattta
     9061 tcagctacat aatcttttaa ttcttttggc atccaaacta ttctttctgg tccaccttct
     9121 gcataagcga attttttaga agatatgaaa tgtcttccgt gtcccataaa tcctggagtt
     9181 tgaactcctc cacctgtcat agaagcaagt tctccgaaag tcataccaac tggagtaaca
     9241 cttgcaaatt ctctgttaac tacaacaaat ccatttgctt ctggcattat accacagata
     9301 cattcgaagc atccacaaga agtcattggg tcttctagta tagagtataa tgtaacagat
     9361 tcaactgcac cttgagatat ttggtttaca gtttcattta ctgaattcca tacacctgtt
     9421 ctatcatcta agcactcgcc tttttctatt ggttgacaag gacctgttgg gtctaattct
     9481 ttagtagcct tagcatctaa ccagctaact gctccacaaa gaccaagtct ttcaggagta
     9541 acaacacaaa cgtgagctgg tgcaaatgat tgacataagt tacaagaata gaaagtatca
     9601 acactttcat caactaatga agctaatctt tcatctctag cattgtactt agctattgct
     9661 tctcctttta attcagaaac tttttcagca tctgtaatta tagttatttc acacttatca
     9721 actactgatt caaattcatc taacatctta gcatataaaa cttctcctat atgctcaagt
     9781 ctaaatcctt tatcaaatgc atctttagag attcttaccc aagccatatc tctttgtcca
     9841 acgtgcatta caccttctat atagtttaag aagtagtgga aacgtctttc aagaactggc
     9901 tcgaaatctt cttgcatatt tttaccagct attttaacta ttacagcaag tggtaatctt
     9961 aatacaccat ctgcatcaac ttcatctata tttggtccta ttatttctat cttatggtct
    10021 tcaacttctg ttgcttcttt cttaacaaca agctcccaag cttcagttct gtttccacca
    10081 aactcagcaa acatatcgct ctttctaatt ctctcacctt caaatgctgc tgcaaatgaa
    10141 actgggatag gtatttcagt aacttttatt tttattcctc tagcttctaa tgaagtagct
    10201 actatcttat cgtaatcttt ttgagttaat aggttcattg gaacttcaag aactgtttgg
    10261 tcagttataa ctgggaatcc taaagctatt gctccagcac ctgcagatac aactaattca
    10321 cttaatggtc caaatgcatt aacaaatgca ggaactctat tagctgtgta ctctaataat
    10381 ccgtttaaat caccaggagt taatccaccg aatattaatg ctgctcttac tgcaacagat
    10441 acaacgtgta taacagaagt tacatcatat cctagaggta taactcttag ctcaagaccc
    10501 atttttactc cagcttctat agcttggtct ataactttac caactaagaa agttagtaaa
    10561 cctttagatt ggtaatcttt tataactttt gctgctgatt ctgcatctgg acactcacca
    10621 agaacaactg caacaccagg tatatctcct gtaactaatg gtacaccaag tgatctgatt
    10681 atagggtcag ttatatgacc tgcacatggc tcactatatg gagcatccat agttgaatat
    10741 tttaatgctt caattacttc tgctgctaaa gctgtagcta aaccagcatt aaaagcatgt
    10801 tctagtaaat gagttctatt tattaaagat tttactactt ctaaagcacc ttctaagtcc
    10861 cctaaagtgt tcatcttttg tcctgttgca gcatatatac aaggtaatga atatgctgta
    10921 tcagggaaag caactttatg ctcttttcca ttcttttcta tagcttcagc taacatagct
    10981 tgagccgcac ctaaagcttg ttctgaccct gtaaagatta tattatatag attcattcta
    11041 tttccccctt taatatttac acctattttt tattaactat accctaaaaa ccctagaaag
    11101 caaatccacc ttcatttaac tctaagaaag agtctgcata taaagatgcc ccgttgatta
    11161 tgtcacaaga ttttacagtt ttcattaatt ctgggtcaca tggattcatt atagctgaac
    11221 taaatccatt agccattgcc attgctaaga atgcactatc taaaacaggt ctaacatgct
    11281 taggacatcc attagatacg ttagataatc ctcctgtagt taaaagtccc atctcagtca
    11341 tcatttttat agcttctaaa acttctactt gtttttcttg catacctttt ataactaagc
    11401 ataatgggtc aaatagtata tcagttggct ccattcctaa cattaagcct ttttctaata
    11461 tttcttggca gtaagccata cgctcatcat tatctcttgg gataccttct tttgcacata
    11521 aacctataac cattgcttcg tattcagctg ctatatctat taaatcaaat cttgaaccag
    11581 catcagcaga gtttattatt ggttttgcat tagttctatc ataaacttta agtccagctt
    11641 cgatagcttt tttattagct gtatctaatg ctataggaac attgttgaac tcagattgaa
    11701 gtaatttgat tccccatgtc attatttctt cgccatctct ttcggcaggt cctatattaa
    11761 aatctatata gtgtgctcct gcttctaatt gctcttttgc tctttttaag attggagctg
    11821 ggtctctttc tgctaatgct tttcttattg aaggtgatat acaatgtatt ctctcaccta
    11881 taatcataaa tttttccatt tataatgtcc ccctttaaat ttaatattaa tagttagtta
    11941 atattttatt agtttgtttg gcatgctttt tcttggtatc cttttaagaa cttaggtaat
    12001 tccatagatt cctctggtcc tataactaca ttccatcctg gtaagttatc ttctatatca
    12061 cctttaagta ctgcaacttt tcctggaatg ataaggtctt tacaattagt tacttcttct
    12121 accttacttt ctttaatgaa agcagagatt gagtttccac caaatttacc agcagcccaa
    12181 gatgtaagaa ctgaatatcc acctgcatct ggtattacta accatactgg aacttttgat
    12241 ctttctatat caccagcaac tatgaagtaa gttaatgcaa agtcaacagt aactaatact
    12301 ggagaatttt catctgggtt gttgattgga taaatctttg gttcaactct cattggtctt
    12361 tgtgggtcag tgtatatgtt ttgtcttagt gcaaataatg gtaatgcctt agcataacta
    12421 atatcatcta ttactattat agaaccgtat tttatagtga atattgatga taaagcaact
    12481 tccatcatag ggtttgaatt agataatcta tttgcaaata ctattgaagg atatccaaat
    12541 gttctatctt gctcttttaa agctgttctt ctaacttgta tagcattagt gtaagtatct
    12601 tttatgtttt ctcctgttac atctaatact aattctttat atccagcagc ttgaattaat
    12661 tcaactgttt catataattc ttctaagcta ccagctttta cacctaatgg taaacttgct
    12721 cctttaacta cttctatcat atctttgtag ttctctttag ttgctccata taccattggt
    12781 ctagcatctt ttaatacttc aacagcttct ttaactactt gtgcatcatc acaagctaaa
    12841 atataagcta cttctaatcc actgcctttt attttatcta ttaattttaa atacgcatct
    12901 ttatctccac aatactctaa aacagccatt tcaactttca tttgttcacc aattcttaca
    12961 tagtcaactt ttttcatgtt agctatttta gcatctactg cttcatcact catacaagta
    13021 cagaatgaaa ctgcatatct atttctactt actaatgttt tttcatgtct aaataatact
    13081 gtttctccac ctagttcata ctcagatgca ccagcaccaa cttttaaagc tttcattaaa
    13141 ggtgcagtag cctctgataa ttttgctata gcgtcatcag acatatgtgg gcatttacct
    13201 acttctacag ctcctgaagc aaccttcata gagaaagcca tacaagttgg gaatccacaa
    13261 tccttacagt ttttctttgg tgttaattta aatatatcta aagcttttaa tgccattatt
    13321 ttttccccct aaccttaaca atttaattaa gctaatgcgt taaccaattc ttttatagtt
    13381 tctattgatt ttggatgacg aagtataact gcgtttgaac cacctactaa aacacttgct
    13441 gcagttgaaa cttccattgc tatagttctt tcttctggac aaccccaatc tggctcatct
    13501 tctattggag ctatagcttc tttaacatga cctacttcaa aagctactgg tgttatgata
    13561 ggcatttgta atgtcttatc attttgacca aatgctgcaa gtctaattct atccatagta
    13621 gatgcaacgt actcatatcc ataaccaact gctgaacatc caacattcat aactatattt
    13681 tcacctttaa cgcctagttg agttaacaat acgtttaatt gtttagctag gtttatatca
    13741 acagaagatt cagctcctac tttatgtgca taagccatac cagctgatgc tcctactcct
    13801 ttgtagttat cttctactgc tgacataaat aagcagttat gtccatccaa tgtttgagct
    13861 aatttttcaa ataatttacc atctttttca tgatttcctg aaccagctac aactaaaggt
    13921 aattttattg cttcaattac tgccttagct acatcagcac attcatcaac tgacttatct
    13981 aatccatttg ggtcagaacc atcaaatttt aaacaaataa aatctgcttg tgtattagct
    14041 tcaacatatt tagcccactc tactggacaa ttagctacat ctttgtataa ttccttatat
    14101 gaatcagtcc agctttcagg ataaacatct gatatttgta tccctatttt tggagaatta
    14161 cctacttctc catcaaaact ataaaaaggt aatacatttt ccccacctaa tttaattgct
    14221 ttttccccta ttcctacttc aacttctgat atttttccag aatatttttg agtagacatt
    14281 ttaaatgcca tatttttttc ccccttaagc ctattttaat tctaatttag caaaaatttc
    14341 tttcatagcc actttagatt ttgaatcttc aggtaaatta actaaaggaa tacctgtaga
    14401 atcatattca tatatcaatt catccatagg tacaacaccg attagctcta ggttatgctt
    14461 ttcaatttct tctttaacac catcattcat aaccccattt ggaactttat ttacaatcaa
    14521 aagtattctt ccaacactta actttagttc ctcagctaaa tctcttattc tagcaacagc
    14581 ttgtatgcta cgtcttgagc aatcactaac caataaaagt gtatcaacat gtctagtgac
    14641 ttttctactt agatgttcca taccagcttc gttgtccatg actaagtatt tgtaatgacc
    14701 agatattttg tttacttgtt ctctaagtat cccatttaca aaacagtaac atccttcacc
    14761 ttctgaccta cccattacta ataagtcata tccttcgcct tcttcgatta tagaatttaa
    14821 tctaaattga agatattgtg cctttgtcat accaccaggg aatgcattgc ctaacttttc
    14881 tctttgattt acttcttctc ttatttctcc tattgttgct tcaacttcga tacctaatac
    14941 ttcatttatg ttagcattgg catcagcatc tacaactaat actggtccct ttttgtcctt
    15001 aaccaaataa tcaatcaaaa gccctgtgag acttgtttta ccagttccac cttttcctgc
    15061 aacagctata ttgtatccca ttttaagact tcccccttaa atctagccac agagccttat
    15121 gtactctgtc tgtctattat aatttaggta cagaatgaac acattctcca tgtacatcat
    15181 gaagtgcttc cattagccct tcagataaac ttggatgtgg atgtattgca tcccctactt
    15241 gttctactgt taatcctaga tgaacagcaa gtgacaactc tgtcaataaa tctgtagcat
    15301 gaggtcctac tactgctgca cctattatct tatcagtttc tttgtcagct ataactttta
    15361 caaatccttg gaaatgtcct atagcttgtg cttttccaag acctctaaaa tcaaattgac
    15421 ctacattgta ttctacacct tcagcttcaa gttgcttttc agtcttacca acaccagcaa
    15481 cttcaggttc agtataaaca catcttggaa ttgctctata atctactacc ttagtcttac
    15541 ctaaagcatt ttcaactgct acgatacctt ctttagaagc aacatgtgct aggaaaggag
    15601 tatctattat atcgcctatt gcgtatatac cttctacatt agtttcaaga tgttcattaa
    15661 ctactacttt tcctctttcc atttcaattc ctatatcttc tactccagaa ttgtcaaggt
    15721 taggtcttct accaacacat actaatgcat attgtgcttc tataaccttt ccattagaaa
    15781 gagttgcaac agccttacca tcaactactt cacaagtttg tactccaata cctgtaataa
    15841 ccttaatttt atctttctta aattgtctaa gtagttgttt agctacatct ttgtcttcat
    15901 ttaatagtat ttggtcaacc atctcaacta tagttacttc tgttcccaag gctctaaaga
    15961 actgccctat ctcacatcct ataactccac cacctactat taacatagac tcaggtatct
    16021 cttcaagtcc aagaacttca tcactagtta ttacaacttt tccatcatat gggaacattc
    16081 ttggtacaac tggaacagaa ccatttgcta gtattatctt atctgctttt atagtttcta
    16141 ctgttccatc atctttagtt acttctatag tgtttttatc aattaatttt ccaaaaccat
    16201 taactaagtt tactcctctt ttttcaaata agaactctat accacttatt aattggttta
    16261 caactttatt ttttctttcc attatggcag tgaagtttgg cttaactgta ccatctattt
    16321 ctataccaaa atcctttgct tcttttacag tattcaatac tcctgaagaa gcaagaagtg
    16381 ctttagttgg tatacatcct gcatttaagc aagttcctcc aactcttctt ttttcaacaa
    16441 ctgttacatc tgcaccaagc atagaagctt ttatagctgc tacatatcct cctggtccac
    16501 cacctactac tactatcttc atctttaatt cccccaaacc taatataatc tacaatcttg
    16561 caatactata aacctgcggc atccagtata gcaggtatat tctcttctgc cccaattgcc
    16621 attatatgaa caccatcaca taaatcttct tcttttaatt gtttgataag ttcccctgcc
    16681 atttttattc cttcacttac ccagttttct tttccagctg ctcttaatct ttcgatttgt
    16741 tcatctggaa caaatattcc tggtacattt gcagtcataa atttagccat tcctggtgat
    16801 tttaaaggta ctattcctgc taataccttg caatccatat cccttgttaa ttctctaaac
    16861 tttctcattg tatttatgtc ataaagtgct tgtgtttgga aaaatttagc ccctgctttt
    16921 attttctttt tcatttttaa taattgaact tctattggag aatattctgg agttactgat
    16981 gctcccagat aaaaatctgg agaacctttt aacttattac cagccatgtc cgtacctgcc
    17041 attaaagtct cagcagtttg aagtatcccc acagaatcta aatcaaacac tcccttagct
    17101 tgtggatggt ctcctacgct agtatggtct cctgttagtg ccaacagatt gtttatccca
    17161 aatacacctg ctgacaacat ttctccttgt atagctattc tatttctatc tctccctgtt
    17221 atttgaataa ctggctctaa tccagcatct tttaataatt tacatgtagc aagagaagtt
    17281 gctctcataa ctgccgattg aaagtctgtt acatttgctg catgaactct tccaactaac
    17341 ggctttgcac attctattaa atgtgaaagg tcagtccctt ttggaggagc catttcagta
    17401 gtaactgcaa attttccact ttctaatgtt tctcttaata agctcatctc taatccccct
    17461 tttaaccttc taaaaaaaac ttttatgaat ttgctgctgc ttctttcttt ttctttgcac
    17521 ttaaacttct tggattattt tgcttagaat agtcttttgg tggtcttatt tctgctaagt
    17581 tatctaattg tcctatagct tctagtcttt catatatctt tatccaagca caatcattct
    17641 ctgagtttac ttcacactta ccatttttag ctccaccaca agccccattc ataagacctt
    17701 tagcacacat agttactgga catatcccac ctgtccaacc aagttcacag tctccacaag
    17761 ccttacaggc ttcttcatat tctccaactc tttgtacttc ccctataaac aaagtattgt
    17821 tggctggata aactggctta tcttttaaat tcttaactat tgtctgtgta ccatctccac
    17881 atgctaaaga taaaactgca tcagcttcct tagtctcttc ctttagagcc tttaaatcct
    17941 ttttagactt taaaaggtta caagcagggt caagcattac atatcctaag atttttttgc
    18001 cttcaccttc aagagtttcc ttcattttta aaacttcttc ttccccacca cttttacaag
    18061 ttgctgcaca ttgattacaa ccaactaaaa ccagcttgtc aaaatctttt aagtacccta
    18121 gcacttcttc taatggttta ttttcagaaa ttatcatatc tacttccccc ctaaaccttc
    18181 cacatatata tatctattta ttgttttgta atttacaagc cttaactaca tgttttgcaa
    18241 gtatagatgt tgtaactgaa ccaacccccg ctggaactgg agttatcatt gatactttgt
    18301 ctaaaactgc atttgtatca acatctccac ataaatttcc ttcttcatca acatttatac
    18361 caacgtctat aactaccgct ccatctttaa caaaactttc atcaaccatc ttagctctac
    18421 caatagctgc tattagcacg tctgcctctg ctgctacacc tgatagattt ttagtttttg
    18481 aatgacatat tgtaacagtt gcatgttcac ttaataaaag cattgatact ggctttccaa
    18541 ctaccattga tcttccaaga actgttacct tacttccttt taaatcaaca ttatagtgtt
    18601 ttaatatctc aactactgct gtaggtgtac atggtggaaa tccactttta tccccttcca
    18661 ttaccttagc agagtttatt ggactaaaac aatctacgtc tttttccggt gcaataacat
    18721 attttataac ttcttcattt aagtgttttg gaagaggtct aaaacataat ataccattaa
    18781 catttttgtc atcattaact ctctttaata catcaatata ttcctcttgt gttatatcct
    18841 cagctaactc taacacttct gttgttatac ctatgttttg acatctcttt agtgctcctc
    18901 tttcataaga taaatcatca cttcttgccc caactctaac tattgttagt ttaggattta
    18961 taccttcttt aattagtaaa tcgacttctt ttattaattc ttcactaatc ttatcagcta
    19021 caggttttcc ttttataatt tgtcctttag ttgacattcc ttccatacat tcacaactcc
    19081 cctacaagca aacttaaatt aatttattct atataccaca tattaataac atagtatcta
    19141 ctttcgtcat ttaaaaatta ttttccaaga gctttttcaa ctttggcata aacttcatca
    19201 caaattttta caccatcttc aactaactta tctacttctg tttttacctt attaacatat
    19261 tctttatctt gtatagaatt tatatttata actacattta attgtccacc aagtatagca
    19321 gctcttaaac actgaactcc tacaccaaca tcacttatag caagtcttga acctttatca
    19381 actaaatctt catgtaactt aatagcttca tagcaaactc ttactatgtt taatggtact
    19441 tcacaagcaa cttttaatgc cttttccatt gtttctgctt ttattctttt ttcttcttct
    19501 gtttctttag gaagcccgta agcttttgat aatggtaaga aacattctgc atcatcatct
    19561 atcattttta ataaatcttt ttctaacttt cctgccttac ttaatatctc ttttacactt
    19621 tcttcatact cagcatactt cttcttccct attgtaaggt tacataccat actacctaaa
    19681 gccataccta ttgcacctac tagtgcagca gctcccccac cacctggtac tgcttctttg
    19741 gaagatagta cttctacaaa atcaacacaa gttttatctg ctattttcat gataatcctc
    19801 cttgaaagga tgtaggaaaa tatctcaaat tgttcgagat attttacgaa ctattttaag
    19861 atatctccta ctctttattt ataaattaat ttccttagaa taatccagct attactccat
    19921 tttcatcaac atctattttt tctgctgctg gaacttttgg taatcctggc atcttcatta
    19981 tttctccagt aagtgcaact ataaatccag ctcctgctga aattgttgct tgtcttacag
    20041 ttattctaaa tcctgttggt ctacctaatt tagtttggtc atcagttaaa gaatattgag
    20101 ttttagccat acatactgga actttagtaa atccaagttt ttctaagtta gctatttcct
    20161 tatcagcttc aggagtataa tctacaccat ctgctccata aatcttagta gctatagcat
    20221 ttatcttgtc ttttatagat aaatcatctt catagcagaa tctaaagtta ttttcttctt
    20281 catccaataa tcttaaaact tctttagcta ctgcaattcc accttctcca ccttttgccc
    20341 atacttcaga aagagcaaca ttaacaccta attccttaca cttgtcttca acaagtttaa
    20401 gttcagcttc agtatcaagt gggaatctat tgattgcaac aactgctggt aatccatata
    20461 cttgagttat gttttcaaca tgttttaata agtttggaag tcctttttca agagcttcta
    20521 ggttttcgtt atttaagtct gctttagcaa ctccaccatt gtattttaat gctcttacag
    20581 tagcaactat tataacagca tctggtttta agtttgccat tctacatttt atatctaaga
    20641 atttttctgc tccaaggtca gcaccgaaac cagcctcagt tattacataa tctgcaaagt
    20701 gcatagccat tcttgtagct ataacagagt tacatccatg agctatattt gcgaatggtc
    20761 caccgtgtac aaatgatggt gttccttcaa gagtttgaac taggtttggt tttaaagcat
    20821 cttttaataa tgcagccata gcaccattag cttttaattg tctagctgtt acaggttcac
    20881 cttcgtagct gtatccaact attatgtttc ctaatctttc ttttaaatca gatatatcac
    20941 ttgccaaaca gaacgctgcc attatttcag aagcaacagt tatatcgaat ccatcttgtc
    21001 taactgctcc atcacctttt ttacccatac catcaacgat atttctaagt tgtctatcgt
    21061 tcatgtctac acatcttctc caagttattt tcttagggtc tattctaagt gcatttcctt
    21121 ggtgaatatg gttatcaagc atagcagcta aaagattgtt agcagctcct atagcgtgaa
    21181 aatctcctgt gaagtgtaag tttatatctt ccataggaac aacttgtgca tatcctccac
    21241 cagctgctcc acctttaaca ccaaatactg gtcctagaga tggttctctt aaagcaacta
    21301 atacattttt gtctagttta gcaaatgcat cagcaacacc tatagtagta gtagtttttc
    21361 cttcacctgc tggagttggg tttatagctg tagttagtat taacttagct tttttaccag
    21421 tctctctttt tagtagattg tagtcaactt ttgctttgta tttaccataa agttctacat
    21481 catcttcacc tagtcctaat ttttttgcaa cctctctaat atcttgaggc ttagcttctt
    21541 gagctatttc aatgtcagat ttaaatccca taactgaatc tcctcccaca acctaaatag
    21601 atttaaaata taatttttgt aaaaattgta ttaatatgta aaaattatat tttataagat
    21661 aattatacat gtaaaattac ttaaaaacta gctactaagc tattaaaata ttcaaactta
    21721 atagctagtt atttatctaa ttacttactt attacctatc tattgcctat gtctaacctt
    21781 taaccaactt aaaatcccaa atcaaaattt ctatctattt tacttatcct taagtgacat
    21841 taatttatct tttattgctt taatctgttc tttcgttgtt tcactagaat catatggaga
    21901 ttgattagct ctatcagaat caataacatc ttggttataa taaataaatc ctaaagattc
    21961 tccatcttct aagttttgga ttataaattc ttcatcttcc ttatttctaa ttttatttcc
    22021 tactacaaat actttattta cacctatatc atgtccaagt ttcttaactt ttctataagt
    22081 ctgtagactt ctctctcctg gttctacaac tactataaaa gcatctacac cttgggctgt
    22141 tcctcttcct aagtgttcaa ttcccgcttc catatccata accactacat ctttattttg
    22201 tagtattaaa tgtgagcaga gtctcttcaa aagaacatgc tctggacata cacatccagt
    22261 accaccagaa tctacggttc ccaatgtaag taatcttact ccattgtatt ctttacagaa
    22321 attttcaggg atatcgtcta ctttaggatt catcttaaac atttttccaa atgaacctac
    22381 agaagcagct gttctatctg aaactaattt tttcatttct gatataggta ctattgattc
    22441 atatacttct tttggaaaac ctagtgctaa agctaaatta gcatcagggt cggcatcaac
    22501 agcaacaact ctgtatccgt cttcagcaaa catcctagag agcattgaag aaaaagtcgt
    22561 tttacctact ccacctttac ctgttattgc tatcttcata atccctacca ccttttatta
    22621 ctatttgctt tttagtagtt aattttacag ttaaatattt tttatactct atatttttat
    22681 acactaaaaa taaactacag ctagtcctta caggaaccaa ttaaatttac cctactagct
    22741 tttcaaagca gcatgtatag ttttattatt ctttaatatt gtttatattt tatttattca
    22801 gtatattcat tatattttga tgttctttac tttaatattt gactttattc aactttattc
    22861 aaccagaaac ttcttataaa aacgtttatt ctataacttc actatttttt aagcttcagc
    22921 cttttctgcc attttttctt caactaatgc ttcaaagtga acacgttttt tctctatatc
    22981 ttctattatt gtagctgcta actcttttgg atttgtattt acagtaaatg tagctccaac
    23041 tttatctttt aattcactag ttaatatatc cactgctctt gaagaaccag ctattggagg
    23101 cattattcct aaataagtgt ctataccaga agctacaaca tagcatccta tagcaactgc
    23161 tttttctgac atccactctg gagctatacc tacaactgga aggtcacaca tatccatatc
    23221 taagtaatta gctgctgctc caactaaatc tagtatacgg cttatatcaa cacaagaacc
    23281 catatgtagt actggtggga ttcctactaa tttacagaca gttgcaagac ctttacctgc
    23341 atatttttca gccgcatcag attccattaa accaaactta gctgctgctg aagctccaca
    23401 acctgtagta actactatta tgtcgttttt gattaattct ttcattattg ttacgtgagc
    23461 ctcatttgaa actcctttag cattgttaca tccaactaca ccagctgctc ctcttaatac
    23521 tccagctttt aaacagtctg ttaatggctt aactgttcct gctgggtcta tatgagagtt
    23581 tacaactctg tctaattgat ttactactgc ttctacacta tacccaactg ttgcgcctga
    23641 ttttaattca ggtataagta cttttgattt atctctattt ttaaagttta aaatagcttc
    23701 tttaactatt gctttagcat catcaagtgc ttgttcttct ctaaattcaa tataagttga
    23761 acctgttatc ttagcttttg gagaagttgt tacaaattta gtatggtaac aatctgcaac
    23821 tctagctaat gcagggaata tacattgaac gtcaactatt acagcttcaa ctgctccagt
    23881 tattattgca agttcttgtt gatggaagtc tcctgctatt tttacaccat gtctcattgt
    23941 aatctcatta cctgtacaac acatacctgc taagtttatt ccatcagcac caacttcttt
    24001 agctaaagct actaagtctg gctcttctga tgctaaaact atcatttctg ataatgctgg
    24061 ctcatgtcca tgtaatatta tgttaacttt attttcttct aatactgcta aattcgcctc
    24121 tgttcttctt ggcactggag ttccaaataa gatatcgctt agacgagtac ctatcataga
    24181 accaccccaa ccatcagcca tagaagttct aagactcatg tgtattaaac tatctatatc
    24241 accagtacat cctatatgag tagagtgcat tattgttgca atttctctat ctatagctct
    24301 tggctctata gcgtattctt tccatatttt ttgtcttggt tctggtgcat tttttataaa
    24361 tcttaatgtc ccaaaaggtt ttccaaattc cattaatgca atttctgcca cttcatgtgc
    24421 tacatcatag atatctctac cttctgtctc tacatcccat tctttagcta aagtaattaa
    24481 cttagcttcg tctcttattt tatagtttcc atttggatca gctaatgcta atgtatgtgc
    24541 tatatctcta gcatggtctg aatgggcagc tgtcccacca gcaaccattc ttgcaaagtt
    24601 tctacctact atagtatgct catctgctcc acataacccc cttggagtct tagggcttat
    24661 tctacatggt cccattccac atattctaca gcaaacacct tgaagaccaa aaccacattg
    24721 tgccttaaag ccttcttttc tatcatacat tgtttctacg ccttcttctc tagctttagc
    24781 tatcatcttc tggctgttta aatcaattgt taacattttt tcatccatat tcctatcccc
    24841 tttttttgat ttttaaaatc ccccaggtga ctgacttcat gtcataaaat aataaaataa
    24901 atgctttcta agttgattat atactaattt tcagtgcttt gctttagatt taaatatttt
    24961 tttaacaaaa ttagataata cataaaaatt ttattttcta cacttaattt aagttgattt
    25021 tatcgcttgt ttttggctat ttgttaatat ctaaacctac ttttttgata cttcagttta
    25081 attaaattat gttttgattt ttttaaatca aatttgaaat ttttctagtc atttttatat
    25141 tattgcagat tgtttgtgta tttattatct ttcactactg tttggactta ttacagattt
    25201 ttactcccta aacttaatta gtaaaaattt cttagaatag cattttttgg actaattttt
    25261 ttgaattttt ttatttttcc tactttaata ttaattatag cttcaaattg aacatttgta
    25321 tatattcatt tgaagctata attatttttt atataaaact tttttaatac agcattaatt
    25381 tagacatttt gactattttt tctactttaa ttcatttatt tcaagcgatt tatcctattt
    25441 catattttta gctacaatag ccccatatgc aatagaatat aatttagatt catgtgaatc
    25501 agctcttgac actaaaacta taggagcttt tgcacccata attatacctg ctgatttaga
    25561 gtctgccata tatgtaaagg ctttccctat tccattacca acctctattg ttggaaccaa
    25621 tatgatatct acatctccag atacttcact tttaaaccct tttatctcac tagcttcttt
    25681 tgaaacagct aaatcaaaag ccagaggacc ttctacaatt acattttcac caaattctcc
    25741 ttctttacaa gcttttgcta acatatctgc atctacagtt gcttgcatct taggatttac
    25801 tttctcttta gctgccaaac atgcaacttt tacagtttcc attcctaaag cttttgcagc
    25861 ttttatagaa ttttttaata tctttgcctt ttgttcataa tcaggagcta tattcatacc
    25921 tccatctgta gttataagta atttatggta tttttctaac tcatatacca taacatgact
    25981 taataaacta tcagttctaa gaccatagtc tttatttaac acttctttta atatgacaga
    26041 tgtatctaat aatcctttca ttacaaagtc agcttcttta cttgatacta atttaactgc
    26101 tatttctgca cactctttga tatcatcctt atccactatt ttgataccac ttaaatcaaa
    26161 tcctatttct tttgatattt ctcttatttt gccttcattt ccaaccaata taggagtaat
    26221 tatatttctt tctacagcat cctttattgc cattaaaact tctttatcat gagctgctgc
    26281 tacagagagt acaattttct ctcctccctt aagttgttct aaaatatcat ctaatttttt
    26341 tatcaaaagt aacccctccc ttatatatat ttaactaaat aataccatat ttgctatacc
    26401 ttttctcaat ttatttttta tgttataaag aatttatata actaaaagac agtttaatat
    26461 tttattctgg gatttcatca atagctctta aaagctttgc aggaacacca cctacaatag
    26521 tattttctgc aacatttttt gttacaactg ctccagcagc gataattgca ttatctccaa
    26581 tagtaactcc tggaactaca gttacattag caccaatcca tacatttttt cctattgtga
    26641 ttggagaagg ataagttgta ccacgtttct ctggtgcaat accatggtta agtgtagcca
    26701 ataccacatt atgcccaatt tgcgtattat ctccaatctc aatccccccc tggtcttgaa
    26761 aatggcaact gctatttata aaaacatttt ttcctattgt gatgtttttt ccacaatctg
    26821 tataaaatgg tggaaacata aaaaatgatt catctacctt ttttccaatt aactcagaaa
    26881 ataaactacg gacttcttct ggttcatgat aagaagaatt taacttactt gtgattttca
    26941 ttgcctcatt actcaactta accataaatt catgtatttc tgatttacta gaaacaggtt
    27001 ttctttgatt gatatgtgtt aaaaattcat tgatattcat tttatacatc ctttcaatat
    27061 gtgctttaat ttatttgtac attctaaata atattttaat aaaaattaat ttaatttatt
    27121 tttattaaaa tatcattgct tcttttagtg taatatacaa ttatatctat atcaaatatc
    27181 tatattaaat acttaactat acttaaaaag catataaatt gatataatta tataataaat
    27241 aagttaatat tgaggaggga taattatgga aataagagta ttaagatatt ttttagcaat
    27301 tgcaagagaa gaaagtatat ctggtgcggc aaccttttta catataacac aaccaacact
    27361 ttctagacaa attatggaac ttgaagaaga gttgggagtt aaattattgg ttcgaggaaa
    27421 tagaaaaatc accttaacaa atgaaggtag gcttttacat aaaagagcag aggaaattat
    27481 atcattagtt gataaggttg aattagaatt tgacaatccc aatgagatta ttagtggtga
    27541 tatatatata ggaagtggtg aaactgaagc tatgcgactt atagctagaa ctgcccatca
    27601 ttttcatcaa aaatacccca atgtaagata tcaccttttt agtgggaatg ctgatgatgt
    27661 gactgaaaaa ttagacaagg gactgcttga ttttggtatt ttaattgaac ctgcaaatat
    27721 acagaagtat gattatgcac aaattcctgc tactgatgta tggggtttac taatgcgtaa
    27781 agatagtgcc cttgcatcac aaagcacaat aaatccaaaa gatttatgca atatacctct
    27841 tattatttca agacagacac ttgttgataa agcaatttct aaatggcttc aaggcagtaa
    27901 tgaaaaacta aacattattg caacatacaa tttagtttat aacgcttctc ttttggtaga
    27961 agaaggtctg ggctacgctc tgtgtttaga tagactcgtc aatactacag aaaacagtaa
    28021 tctttgtttt agacctctat ctcctccttt agaagctaaa ttaaatatta tatggaaaaa
    28081 acatcaaata ttttcaaagg cagcagaaaa atttttactt caaatacaaa aagatttttc
    28141 ttctatcatg ttggatacat ctaagttgga tacacctaaa gaaaaataaa tcataataaa
    28201 aagtgagagt gtctcaaaat gaactttgca ctgtataagg cactcttttt tatacaaagt
    28261 aaaatatatg ttcatcattt cagcactaaa aaagaggctt atctctattt tgagatagcc
    28321 ccacttaacc aataaaatta aatacaactt aacaatatcc ttacttattt attccaagtt
    28381 ctcttagaca agcaatcgta atttcatctt gtggatttaa ttcataagct ctttctatat
    28441 agtaagttgc atcatcaata tcaccattat ttaaataagc cattcctaaa ttgcaaagta
    28501 tttctgggtc ttcctttatc ttagccgctt gttcaaaata ctctattgct ttatctaaat
    28561 tattcttata agcctcacaa agccccaatt ccactatagt atccacctga ttaggcttta
    28621 ttatcaatat cttctcaaga tacatcttag cctgctctat ttcgcccata cccttatatc
    28681 caagtgctat cataaacagc aagttccacc aatccatatg ttcttcttct aatggaagta
    28741 acttctctaa tccttcctta aacttacctt ggaatacaag tgtatatcct tcttcatatt
    28801 gaactttaaa gtccatcttg cccagattct cttgtacctc agctactaaa tcagcatcta
    28861 accctagcct taacgcttct tcccaagtca gcttagtctt taaatattga ccttgattat
    28921 aataatggta gcctaagtga taataaccta atgcaaaatt ctcatcaaca tcaattacct
    28981 tttcaagctt agccatggct tcaagtaaga atgcattcat tgccttatca tccatatctt
    29041 tttgatactg tttagctatc tcttggcaaa caatcgcata gttatacatt gcatctaaat
    29101 catctggata cattgttata aatgctttta tatatattaa agaatctgta tgttcaccaa
    29161 tctcaaagta ttttctcgac atatatccca tatacgattt caaatccaaa tcaatatctt
    29221 ttgataaagc atttaaaaac ttctcatact ctgcattgtt tttaaactta ctatctattc
    29281 caattatata tatcattgca tctgctatag acattgaatt taacttatct tgagcagtct
    29341 tttcttttat cccttttact aatacctcat tttttatagg tacatctaat ccaccttttg
    29401 gcacttcata gctttttaat ttaaactctc caccatgttt tatagttata aaagctaatt
    29461 cttctgcttt ttttagcaaa tatttttcta tcttaaaatc cattttatcc tcctaaatac
    29521 ttaaatctct actttatgag ttttagattt ctcaaatatt tttttatcat catactcaaa
    29581 taagactaca ttttctactt ctcttatttc tgtatttata tcatttttta aatccacaac
    29641 attaaatcta aatggctcaa aatgaacata ttttattata tgtttagctg gtttatcaac
    29701 aaaactaggt aaatatgttg ataagttatc attatcttgt aaaaatacat ggcatctatt
    29761 cttaaaatca tccacatcta gcttattaaa aaactgtggt atatttgatg ttttacccag
    29821 tgatatatag tcatatttta atatatcgtt gaatacatca ttatctatgt tgattttttc
    29881 attatagaaa tccatcaata ttttatataa ctgattcttt ccttgtgcca aatcaaagta
    29941 gccattttca tcaaaatact tggcaaaaac ctcaaagaat ttaaaagggc tttttttata
    30001 aaatctgcct ataatatatc tcatagataa cacaaagttt ttagaattgt agtatctctc
    30061 cagtatatct tctatatcct ttagcttcaa agtttcttca tagcttatat aattattgta
    30121 taaaaactca tatggagcat aatccttata tttaaaacca tgctcatctg caacttttct
    30181 catacctgtc cctttaatca tctttaaaaa gcctaattgc agatgctcta tacctagatt
    30241 aaatacatca ttaaaagaat tttcaaagct cttataatct tcataaggca gtcctgcaat
    30301 taagtctaag tgttgatgta tatttctata agatgctaca gtttgtacaa catgagacaa
    30361 ctttttaaaa tcatcccttc tacctactgc atcaagtgtt ttttcattcg ttgactgaac
    30421 ccctatttca aattgaaaaa gaccttcttt acaatcagcc aaaaactcaa gcatcttatc
    30481 atctatcaaa tacgctgtaa cttcaaaatg ataagttgta tatccattat catttttcat
    30541 aagaaaatcc atgatttcca tagccacttt tctatttgca ttgaatgtcc tatctataaa
    30601 ctttatttgt gatactcttg catctattaa agcttttaaa tcactcttta tcctgtctaa
    30661 actaaaatac cttagacctg gaatagtaga tgataaacag tattggcagt taaaagggca
    30721 acctcttgat gattcataat acactattct attttcatat tcttttggat tcaagttttc
    30781 ataaggacta ggaatctcat ccaaatcttg aagtaattcc ataggcttat tcactattat
    30841 ctcattgcct tgtctatata caagtccatt tacatcattt atttccatct ttccttgcaa
    30901 gtgaagtact aaatctctaa aaattaattc tccctctcca taaagtatat aatccacaaa
    30961 atcatacttt ttcattgcct cataactatc ataactcact tccggtccgc ccaaagctat
    31021 tttagtatta ggtctaattt tttttagatt atcacaaagt ttaactatat ctcccacatt
    31081 ccagatatat gttgagaata atattatatc atattcattt ttatatatat cctttaaaat
    31141 atagtccaaa tcgttgttta tcgtgtattc tttcatatta acttctatca aatctcttac
    31201 aaattctttt agatatctta tagccaaatt tgtatgaata aacttggaat ttaatgttgt
    31261 taataaaatt ttcaaatatt tctcacctct ttttaagatt atactgtctt tttgtacccc
    31321 ttataggtta aaatagtata tgtaaagtct aaataatatc tatataatta atttattaat
    31381 ttcaagtaat gtgaggaaag gaagtttttt atggaattaa ttgaaaaagt atctatcaac
    31441 tctttatcaa aaagagattt actacttatt ataaagtctc ttgaatacac taatgaaaat
    31501 actcaaatta gtgatttcat tgaccttagg aataatatag taaaggaatt atgttttt
//
LOCUS       DAEPKC010000039        31392 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.039, whole genome shotgun sequence.
ACCESSION   DAEPKC010000039 DAEPKC010000000
VERSION     DAEPKC010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 31392)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31392)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31392
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.039"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(<1..444)
                     /gene="pilM"
                     /locus_tag="KR294_001851"
     CDS             complement(<1..444)
                     /gene="pilM"
                     /locus_tag="KR294_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilus assembly protein PilM"
                     /protein_id="HBH0239931.1"
                     /translation="MAIIKKILNLEINDDYIRLVFLRKSHKKVFIDKSIIKEINFDIK
                     NDSNSIEKIKYIEDVVRFVKEEIGKSKILYKNLYFNIQIQDIVIRNVEVLNTKKKRDI
                     LSMIEFEITQYIPININNYSIKYKVINSKNDKLNIQVILFPKSIIQ"
     gene            complement(497..856)
                     /locus_tag="KR294_001852"
     CDS             complement(497..856)
                     /locus_tag="KR294_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HBH0239932.1"
                     /translation="MINLINKKRKGFTLVEMIVVVTILGVISSIALVKYSKVQESAKL
                     NADYTNAANIVTAASMAINDDEKTIDSLSVETLKEKGYLNTVPVPQSTSGKFELVIND
                     SGTDISVNINSKQFYPK"
     gene            complement(910..1995)
                     /locus_tag="KR294_001853"
     CDS             complement(910..1995)
                     /locus_tag="KR294_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HBH0239933.1"
                     /translation="MRLSKNIFYNLEKFYLVLNRISDKEIRVICKEIGILLESGCEIT
                     KIFEIIESQSSKKAKNLLSIVSNHIQKGNSIAESFQITGIFSKFFISMIKAGETSGNL
                     DIIMSDLSNYYDKEYKLKMKIITISIYPIILIILSILSMLFIFVFVIPNFQVVFTNNG
                     IEPPLITRVLMGISTVVTNNLAYIIFSFILFSIGSIYFFITNDNIKKLINSLKFKIPF
                     IKKINQLVATTRFSRALSVLISSGIQIVEAIDMSASVIDNEFIYERLKISNNYIKKGN
                     SIGKSLNLANVFPKLFISMANTGEESGKLDKSLNVINKFYENELNNKIEQIMKFIEPM
                     LIVFMGLIIGTFILAMVVPMFDAITNF"
     gene            complement(2166..3545)
                     /locus_tag="KR294_001854"
     CDS             complement(2166..3545)
                     /locus_tag="KR294_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HBH0239934.1"
                     /translation="MIKIILEESSLPMLIPEKLAKKYNVFPVEFQDDNLVVEIEDEDI
                     YALQDLRLATGKEIILKKEKKELISEKIEKYYNSFELDEDYAKKLFENLLEKAIKENA
                     SDIHIEPFKEHLIVRMRVDGELKEVSKFLVDVYPSLSTVIKLKASMDITEKRLPQDGR
                     VDIKLGGNLIDIRVSSIPTVYGEKIVLRILNRDTFLKDKLELGFSEEAIKSINRIINK
                     RAGILLVTGPTGSGKTTTVYSLLNDLKGINKNIMTIENPVEYKMDGISQIQVNSKVGL
                     SFDVGLRAILRQDPDIIMVGEIRDAETAKIAVRAAITGHLVISTLHTNDAVSSIARLL
                     EMQIPPYLLNASLIGVISQKLVRKVCNHCSHEIMIKDNFSGDVNTKVAVGCEKCNDKG
                     YFGRTAIYEILEINDDIKTCIRNMEDSSTIKDVAQNNGMITFEDSCKRLINEKITTLE
                     ECLVVNEMI"
     gene            complement(3538..4218)
                     /locus_tag="KR294_001855"
     CDS             complement(3538..4218)
                     /locus_tag="KR294_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF881 domain-containing protein"
                     /protein_id="HBH0239935.1"
                     /translation="MKKQYVFIILASTILGILVGTIFRDYSNEETVYTSKDKSIRKEI
                     KMTRKSIKELTKEKDKLDKEINSMKQNQKNSEEISEIETLRDSLSYSDVKGSGIILSI
                     DAIDEKTGNIANSIDYNKILVKVINELKVNGGKYIEINGQRINQYSEVVLAGSHININ
                     GVPVAQPYEIKCIGDKEKLSNYVDKGSKYLDSIQTNYPMKISIKTEENISMKKMNIPN
                     KLKYIKGD"
     gene            complement(4610..5689)
                     /locus_tag="KR294_001856"
     CDS             complement(4610..5689)
                     /locus_tag="KR294_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH0239936.1"
                     /translation="MEGKVKKAFPGGNTSQGSYSFFDYIIPENVKRVFCLKGGPGVGK
                     SSLMKKIYKEFLHRGYDIDLYHCPSDPSSLDGLVIKKLGVVLMDATAPHTMDPKLPGA
                     LDEIINLGDYWNTEELEKNKQEISVYDKDISNSFKRAFKFLKSAEPIFRDIEEKYSDC
                     MDYGKVNLVTEEFIKRLFDGVKSTGNLKREKHLFGSAITPVGCLDYTENILKDVKKVY
                     YLDGEIGTGKTTLLNKVYKKAIEKGLNVEVYHYPLIPEKIETVLLTDLDIGITISTTF
                     KEEDTIDLNQFLNREKLLKYEEDIKFDEKVLDDLICWAVLNLKRAKSKHDIIESYYSP
                     NMRFDEVGKLRDKLIKRILKYEENL"
     regulatory      5977..6092
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            6267..7637
                     /locus_tag="KR294_001857"
     CDS             6267..7637
                     /locus_tag="KR294_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH0239937.1"
                     /translation="MKQKWIVLIIICIGVFMSTLDGSILNIANPTIAADFKINMSQIQ
                     WVVTAYMLVVTATMLFFGKLGDKVGSNRLYTLGFFIFTIGSFLCSMSNNLSTLISSRI
                     FQAVGASILMATGLGIVSNAFPANEKGKAIGITGAVVGIGNMSGPVIGGIILEHFGWP
                     SIFIINIPIGIIAVFLGIKFLPKPVLDEQNKSFDIPGLLLFASCTTLILLAMNEKGNT
                     RLYLGITALIIFLLLALREVKFEQSFIDLPLFKNRNFTVGNIIGVACYFPQMAVSFLL
                     PFYLEQLKNLSPMMAGYVMTVHPLIMVLIAPIAGSLSDKHGAKNILTASFSFMTISLV
                     GMALLKADSPLYLLIVCLVIFGLGLGAFSSPNNSSILADVPPQKQGYGGSFLATIRNL
                     SFALGTAFFSSFFAQSLTYNQKFKSHTSAYVIASNQSYWIAASVCFVGLILTVFFMRK
                     TDKSIS"
     gene            complement(7903..8514)
                     /locus_tag="KR294_001858"
     CDS             complement(7903..8514)
                     /locus_tag="KR294_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HBH0239938.1"
                     /translation="MKIRSSEITMSAVNKSQYPAEGIPEIALAGRSNVGKSSIINTLL
                     NRRNFARTSQTPGKTRTINFYLINNEFYFVDLPGYGYAKIAKSEKEKWGGIMERYLES
                     RQELCSIFLLVDIRHEPTADDKLMYEWIKHFGYNCVVIATKADKISRGQYQKHISIIR
                     KKLQMESSEKVIPVSSLKKTGVEELWEEIVNQYNQHGYEITVD"
     gene            complement(8504..10867)
                     /gene="lon"
                     /locus_tag="KR294_001859"
     CDS             complement(8504..10867)
                     /gene="lon"
                     /locus_tag="KR294_001859"
                     /EC_number="3.4.21.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase La"
                     /protein_id="HBH0239939.1"
                     /translation="MEQNYTKIDHELPLIPLRGLAIFPYMILNFDIGREISLKALDQA
                     MMDEELIFLTSQKEAEVDEPGEEDFYHVGTICKVKQMIKLPGDTVRVLVEGVSRGRVK
                     KIEQEDGYFRAVIEEIVFDSDNLDSETEVEIEAFVRNVFDAFEEYINIGNRVSPEILI
                     SLADIEDVDRFIDTIAANIYLKSSQKQEILEEFDIRKRLELIYSILLEEIDILKIEKK
                     ITLRVKKQMNKVQKEYYLREQLKAIQKELGEEEDINSEADEYREKLKKIKAPKTTKEK
                     IEKEIDKFSKISSMSPDVSVSRNYLDTIFSLPWNKETKDKLDITKAKDILDEDHYGLE
                     KVKERILEYLAIRTLAKSLKGPIICLVGPPGTGKTSIVKSIARALNRKFVRISLGGVR
                     DEAEIRGHRRTYVGSIPGRIINGVKEAQTKNPVFLFDEIDKMAADYKGDPASAMLEVL
                     DPEQNKDFVDHYLEIPFDLSKILFVTTANSLSNIPRPLLDRMEVIEVSGYIEEEKLNI
                     AKKYLLPKQIKEHALKENFIKIDDETLRSIINHYTREAGVRTLERTIGKICRKVAKKY
                     VEDPTLEEVVINKSDLETYLGKDMFKYQLAEVNPQIGLVNGLAWTEVGGVTLEVEVNV
                     LKGKGEIVLTGKLGDVMKESAKTGISYIRSIVDKFDIDPEFYKTNDIHIHIPEGAVPK
                     DGPSAGITMALAVISALTKRPVPGNIAMTGEITLRGRVLAVGGVKEKLLAAHRAGITK
                     VLIPKECEADLDEIPENVKEKMEFVLVEHMDEVLEQALLKSGENNEN"
     gene            11047..11559
                     /locus_tag="KR294_001860"
     CDS             11047..11559
                     /locus_tag="KR294_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HBH0239940.1"
                     /translation="MLKLFLTFLKIGAFTFGGGYAMVPLIQDELVNKQKLLEQEEFID
                     YLSIAQSYPGVLAVNISVLLGYKLYGIPGVLICTLGSALPSFCIVLVLSYLYFKNSSS
                     KILDGFFKGVAPVVIALILYSFTSMFKKLPKSKTNILLLIIAVLSVGVFNISPIYLII
                     GGGVYSLCQK"
     gene            11547..12074
                     /locus_tag="KR294_001861"
     CDS             11547..12074
                     /locus_tag="KR294_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HBH0239941.1"
                     /translation="MSEIILLFLIFLKIGAFSFGGGYAMLPFIQQEFISKYHFITNQE
                     FLDLLAISQSTPGPVAINSATFVGFKTAGFFGSLAATIGVTIFALIGLTIISKLFSKF
                     KNNKKVENLLTVLRPITLGFILSAAFSSAKEVNWDLYGIIAFIASFYLLYKGKIGSIA
                     IVFVFGILGILLTFL"
     gene            complement(12145..13395)
                     /gene="clpX"
                     /locus_tag="KR294_001862"
     CDS             complement(12145..13395)
                     /gene="clpX"
                     /locus_tag="KR294_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HBH0239942.1"
                     /translation="MSKYEEKRQLKCSFCGKNQDQVRRLIAGPNVYICDECVELCDEI
                     IQEEIEDTIDEDTTSLPKPKEMMEILNDYVIGQEKAKKALSVAVYNHYKRIYSKKSSS
                     KDIEIQKSNILLLGPTGSGKTLLAQTLARTLNVPFAMADATSLTEAGYVGEDVENILL
                     KLIQAADFDIEKAERGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKILEGTVAN
                     VPPQGGRKHPHQEFLKIDTTNVLFILGGAFDGLEKIIQKRGGDKTLGFGAKIESKKEL
                     DLGKLYEKVLPEDLLKYGIIPEFIGRIPVLATLELLDEDALMQILQEPKNALVKQYKK
                     LLELDDVELEFEEGALRAIAKKAIERNTGARGLRSIVESVMMETMFEVPSRDNIKKVI
                     VTEKSVNEDSVNPIIVLKDQEESA"
     gene            complement(13414..13998)
                     /gene="clpP"
                     /locus_tag="KR294_001863"
     CDS             complement(13414..13998)
                     /gene="clpP"
                     /locus_tag="KR294_001863"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HBH0239943.1"
                     /translation="MALVPVVVEQTGRGERSYDIFSRLLKDRIIFLGDQVNDATAGLI
                     VAQLLFLEAEDPDKDIHLYINSPGGSITSGMAIYDTMQYIKPDVSTICIGMAASMGAF
                     LLAAGAKGKRLALPNSEIMIHQPLGGAQGQATDIEIHAKRILKIKETLNEILSERTGQ
                     PLEKIKMDTERDNFMSALEAKEYGLIDEVFTKRP"
     gene            complement(14148..15434)
                     /locus_tag="KR294_001864"
     CDS             complement(14148..15434)
                     /locus_tag="KR294_001864"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HBH0239944.1"
                     /translation="MKAELIKKEGNKVTLKITVDNNKFEAAVNKAYNKSRNKYNIPGF
                     RKGKAPRIVIETQYGKGIFYNDAIEILFPEVYPEAIKELDIDPIDNPDLDIEEISKDN
                     GLVMVLNVEVKPEFELGNYKGIEIAKVENTVSDENVDAKLQEMVEKNARLVSVEDKAL
                     EDGDTAIIDFEGFENGVAFDGGKGENYNLVIGSNTFIPGFEEQLVGKKAGEEVEVNVT
                     FPEEYHSQDLAGKPVVFNVKINDVKVKELSALDDEFAKDTSEFDSLDELKADVRAKLE
                     EEAKNRADAETRNSVVEKVAENTEIEIPEVMIQHQIDNMLNELNYQLQYQGFGLQQLL
                     EMTGRTMEELREERKEDAKKLVKSSLVLEAITKAEGIEATEEEFKAELEKMASAYNME
                     VEKIEASLRDADKEDIKGQIKIRKTIDLLVDNATIA"
     gene            complement(15628..16098)
                     /locus_tag="KR294_001865"
     CDS             complement(15628..16098)
                     /locus_tag="KR294_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBH0239945.1"
                     /translation="MKIGIVSDTHMMIKNMEKTIPYLKECDLIIHAGDNFTDSRYIHS
                     MTNVGIIAVKGNCDFDAVEEEVVFEVANKTIFLCHGDKYGVKYGTHMLEKKATEVDAD
                     IVIFGHTHTPFREIKDGVLYINPGSTSLPRGVSYKSFVIMDIEEDDIKIEEIRI"
     gene            complement(16098..17447)
                     /gene="rph"
                     /locus_tag="KR294_001866"
     CDS             complement(16098..17447)
                     /gene="rph"
                     /locus_tag="KR294_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HBH0239946.1"
                     /translation="MTRSYDRSNEQIRPVKITRDYTKYAEGSVLIEMGETKVICTASV
                     EEKVPPFLRNSGTGWINAEYSMLPRATQQRKIRDASRGKIDGRTQEIQRLIGRAIRSV
                     VDLNKLGERTIWVDCDVIQADGGTRTASITGAFVAVAEAIYKLYKAKIIKEMPITNFV
                     SAISVGIVNGIHMLDLCYEEDSKAQVDMNIIMTDKCEFVEVQGTGEEKPFSRADLNLL
                     LELGEKGNKELIRLQREALGEISDEILGMDYGNEVVIATNNAHKLEEIGEILKDFEYK
                     VYSLKDVDLAGIEIVEDGKTFEHNALIKARTIAKKTKLIAISDDSGLEVDALGKKPGV
                     YSARYAGEHATDEENRKKLLKAMQNIPMSKRNARFVSAIAVVFPDGKEFVVRGICEGM
                     IGFEEKGKNGFGYDSLFIVKGYDKTFGEIPSVIKNSISHRANALKLMKQEFIKRVVK"
     gene            complement(17607..19631)
                     /gene="ligA"
                     /locus_tag="KR294_001867"
     CDS             complement(17607..19631)
                     /gene="ligA"
                     /locus_tag="KR294_001867"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HBH0239947.1"
                     /translation="MSVKDEINKLIETINYHNERYYNQDSPEISDYEYDKLMKELISL
                     EEEHPELKRIDSPTNRVGGKPLDKFNQIVHKTPMLSLSNAFSEQDLRDFDKRVQEYVG
                     ENVEYVVEFKIDGLSVGLTYNNGEFEKGATRGDGVVGEDISQNLMTVKSIPLKINDKK
                     ELIVRGEVYISKDNFRKVNEQQEEQEQPLFANPRNLAAGSLRQLDPKLTAKRPLDIFV
                     FNMENIEEYDLESHSESLEYLEKLGFSVSQSYKVCKSIDEVIEHIEYWTDNRGNLDYE
                     IDGMVIKVNNIKQRDEMGYTAKSPRWAIAYKFPAEKKKTKIVDIIVEVGRTGTITPSA
                     ILEPVRLAGTTVSRATLHNEDYIREKDIKINDTVLVQKAGDIIPQVLEVIKEERTGDE
                     IDFKMPEKCPVCSEPTIRLEGEAAVKCINMSCPAQIRRGIIHFVSRDAMNIDGLGESI
                     ITLLLNEKIIQDVSDLYYIKKEDVVDLERMGEKSADNLINSIEKSKENDLWRLINGLG
                     IKFIGVKAAKILAYNFKDLDEVISATSEQLEELEEFGSIMANSVVEFFKEDKNMNVIN
                     KLKNVGVNTKSLDNTGEKVEKIFEGMKIVLTGTLPTLKRNDAKDMIEKRGGKATSSVS
                     KSTTFVLAGEEAGSKLTKANDLGIKVIDEERFLELLKLSSKDEVKAVLES"
     gene            complement(19817..20755)
                     /locus_tag="KR294_001868"
     CDS             complement(19817..20755)
                     /locus_tag="KR294_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HBH0239948.1"
                     /translation="MKVLFTINYGKEKFDKIRELGYDVIHYSEDSIENNEDVNTADVL
                     VTYNPFERLDISKMKNLQYIQTTSVGIDQLPKEEVLKRNIKIANNRGGYSVPIGESIV
                     LYILEIYKNSAKFFKQQQNKEWKMDFSVSELYGQRVGFLGTGTISSEAAKRLKAFGVE
                     IWGVNTDGSSKKYFDKCFATEDMNIVFEECDIVVVAMPSTKSTDGIVNKDMFKLMKDG
                     SVFINVGRGNTVNQKDLEECVEKFRGVALDVFESEPLNKDNKLWECENVIVTPHNSWV
                     SDKNKERTFNMVYNNLKHYIMENKPVDNVVDISRGY"
     gene            complement(20857..21279)
                     /locus_tag="KR294_001869"
     CDS             complement(20857..21279)
                     /locus_tag="KR294_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3783 domain-containing protein"
                     /protein_id="HBH0239949.1"
                     /translation="MSFEKINNNNLDKIHNRKCIMLVNFNKKELSLIKNVSNFAGIRD
                     HIILSDKNGENIIRDILDGNISNECENGIKSKSVIFNNTPSTQVNAFLEGLKKVRINR
                     PFTAMVTETSIDWTLNNLIENLVQERNAMSLGKTIEHK"
     gene            21467..22750
                     /locus_tag="KR294_001870"
     CDS             21467..22750
                     /locus_tag="KR294_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugated bile salt MFS transporter"
                     /protein_id="HBH0239950.1"
                     /translation="MNTLLNNKFSIKNFSNAWVIVLGCMLIQAVPFSIVASIQPQFIS
                     YVVEGEGFSLASFSLIFTIGTIASAIASPFIGVLFSKVNIKILYLLGCIISSIAFATF
                     SICTELWQFYTVSCIVQIGATIISAIGIPVLISAWFDEESKGKALGFAFAGGSIGSIF
                     LQPLAVRLLATQGYSRSYLIFGIIALIVGIPVILFILRMPKDINEKVKSKGKKEKASD
                     TISPSVWGYTLKEAKKIKYFWIMTIGFIFVGIYVSSLSVQYPTYLRNYLNPILIGTVG
                     STFALFALIGNLFGGLLFDKFGQTKPLIISFVLVLIATLSLLLVDKSSTFAFVFAILK
                     GLSVFAYMIGPAYLTGSFFGQKEFGSIYGIVQLIFAVGFALGSTLFGLLVDNFGYRFS
                     WSIIILSVIIAYTLLIITSIGMKKLNKERLDKLMQ"
     gene            complement(22828..23343)
                     /locus_tag="KR294_001871"
     CDS             complement(22828..23343)
                     /locus_tag="KR294_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HBH0239951.1"
                     /translation="MNYFVIADPDKCIGCRTCMIGCVVAHSDEDIFYQNLDEINFNPK
                     LSVIKTKEVSAPIQCRHCEDAPCAKACPNGGIVRVGNTIKINEENCIGCKTCMLACPI
                     GAIDIVTLKDVDEGKLCFRERMTANKCDFCIESPEGPACVNVCPTKAFTIVKDEDIDS
                     KVKNKRKLAIL"
     gene            complement(23343..24719)
                     /locus_tag="KR294_001872"
     CDS             complement(23343..24719)
                     /locus_tag="KR294_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron hydrogenase small subunit"
                     /protein_id="HBH0239952.1"
                     /translation="MIINIDKDLCTGCRECSKVCPVNAIEGEEGKPQEINLDRCVMCG
                     QCVQTCKSYASVIDEGFEFLQEKKQEREIPESINEPIFAAYNVCDIDKVKKALSDPNV
                     FTMVQCAPAVRVALGEDFGYYLGYLGAGKMAAALRALNFDRVYDTNFAADLTIMEEGS
                     ELIKRVTEGGTLPMFTSCCPAWVKFMEKNYPKLTNHLSSCKSPQQMGGAIFKTYGAEI
                     NNVDASKIFSVSIMPCTCKKYECDREEMDSSGYRDVDVVLTTRELAYLIKDMGIDFKN
                     LREEKFDSPLGSYSGAGTIFGVTGGVMEAAIRTGYELITGESIPDVEVKQVRGENGFR
                     KSTIKIGDLDLRVGVVSGLKNVIPVLEDLEKGKLDVDFIEVMTCPVGCVSGGGQPKIL
                     LEEYKELAYENRTKATYVHDEHLAIRKSHENPDIKKLYDEYLVEPLGEKSHHLLHTTY
                     CIGKEVAK"
     gene            complement(24744..25295)
                     /locus_tag="KR294_001873"
     CDS             complement(24744..25295)
                     /locus_tag="KR294_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HBH0239953.1"
                     /translation="MKNKIGSFVIADPNKCTGCRACEVACFTMHNQHNNVGYTVGTVD
                     IPVIPRLYLVKGDNFCMPIQCRQCEDAPCLNSCPQKAIVKENNIMSVNEEKCIGCKTC
                     LLACPFGAIDLLPQYEDGKEVEQVILDENKKIAYKCDLCKDNEKIACISACPQEALKL
                     VTPIDDKKAKNRQAALSLLLTNK"
     gene            complement(25353..25568)
                     /locus_tag="KR294_001874"
     CDS             complement(25353..25568)
                     /locus_tag="KR294_001874"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239954.1"
                     /translation="MQIHRELSKSENEYMCTKKEEQRYSKCEICGVLIDDTDKVYNNT
                     YNLCKKCKRNISTEKIVKYINIYDESK"
     gene            complement(25537..26370)
                     /gene="fdhD"
                     /locus_tag="KR294_001875"
     CDS             complement(25537..26370)
                     /gene="fdhD"
                     /locus_tag="KR294_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase accessory
                     sulfurtransferase FdhD"
                     /protein_id="HBH0239955.1"
                     /translation="MNNIYSKTKLQENSKDKVFENSYSLVDYKYLNSFNVEVSKINEH
                     EVSIDNEEIIAEYPLSFILNDKYINTFLCTPYNLEELIVGFLKTKGYIENKKSLLKFE
                     INESERFAKVTIQEKQKNQDEQIIFLNSLDYITCAPVKSNIKINYDTIYSIMDRNLNS
                     SELFKNTGGVHSVSVFNFDKKIVTCEDVARHNAMDKAIGFCVLNDITLKDKIVAVSGR
                     ISLEMILKAAMTQIPIVVSKSAPTNLSIELSKKLNITLIGFVRGRRMNIYANPQRVIK
                     K"
     gene            complement(26419..28563)
                     /locus_tag="KR294_001876"
     CDS             complement(26419..28563)
                     /locus_tag="KR294_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:complement(28147..28149),aa:Sec)
                     /transl_table=11
                     /product="formate dehydrogenase H subunit alpha,
                     selenocysteine-containing"
                     /protein_id="HBH0239956.1"
                     /translation="MEKKILTVCPYCGAGCQLYLVVKDNKILRAEPANGRTNQESLCL
                     KGRYGWDFLNDPKILTPRLKKPMIRKQGVLEEVEWDEAINYTASRLNEIKEKYGPDSI
                     MGTGSARGPGNEANYIMQKFMRATIGTNNVDHCARVUHAPSVAGLAYSLGSGAMSNSI
                     PEIENADVLFIFGYNGADSHPIVANRIVKAKKNGAKLIVTDPRVTESARIADIHLPIK
                     GGTNMVLVNAFGNVLIEEGLYNKEFVQNHTQGFDEYKEIVKPYTAKYAEKITGIPEEL
                     IRKAMREYAKGKKAMILYGMGVCQFGQAVDVVKGLASIALLTGNFGRESVGIGPVRGQ
                     NNVQGACDMGALPNVYPGYQNVTDDKIREKFEKAWGVKLSPNNGYSLTQVPNLVLKEK
                     KLKAYYIFGEDPVQSDPDASEVREALDELEFVIVQDIFMNKTALHADVILPATSWGEH
                     EGVYTCADRGFQLMRKAIEPQGDVKPDWQIISEISTAMGYPMNYKNTKEIWDELRQLC
                     PSFLGATYEKIETQGCVQWPCKSESMEDKGTMYLYEGQKFSTPNGKGNLFAAEWRPPM
                     EVEDDEYPFSLCTVREVGHYSVRTMTGNCRTLSSLEDEPGRVQINSNDAEKLGIEDDE
                     LVRISSRRGSVITRATVTDRVKEGATYMTYQWWVGACNELTIANLDPISKTPEYKYCA
                     VKLEKLEDQELAEKCVREEYQSLKDKMTATNI"
     gene            complement(28814..29872)
                     /locus_tag="KR294_001877"
     CDS             complement(28814..29872)
                     /locus_tag="KR294_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HBH0239957.1"
                     /translation="MDRLKNIRKSLLQYTFLFLLIGITIYLVFKTLDIKMLSNVMVMV
                     DKKFLFIGALAIMCHIMLEGVVMKIIIESTHKVNIRFIGFKLAIMGFYYNLITPFASG
                     SQPVQIYVLKKCKMPLSKASAVVTNKSIIFQIVVTFYCTILVLMNFAMLEKQMKMIMP
                     LVFLGIAINSFVLIMIILVILNPKKIKYFMRITIKHLSKIKFLKFLDNKIESIESFID
                     DYSKAINFFAKNKKVLISTIIVTFIQLSAYFSVSFWIYKAFNLQGYSYIYILTLQAFL
                     YMAISPIPTPGNVGANELAFFTIFKSVFPQPLMGYAVFLYGGFMYYLILIGSGIFTVI
                     THYRMKNRIGRNIVLSEN"
     gene            complement(30083..30742)
                     /gene="cprR"
                     /locus_tag="KR294_001878"
     CDS             complement(30083..30742)
                     /gene="cprR"
                     /locus_tag="KR294_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CprR"
                     /protein_id="HBH0239958.1"
                     /translation="MSKILVVDDELDMLKLIENVLKRDGHEVKVISDVEKAMNMDFNY
                     FNLIILDVMMPKMDGFEVCKTIRNKVDCPILFLTAKNMESDIMYGLGIGADDYITKPF
                     GVGELRARITAHLRRESREKKNLLTISNVQFNFLGKEVSIDGKKINFTKSEYLICEFL
                     AKNKGQVFSKERIYESVYGFDGESDISTITEHIKNIRSKLKQYDIYTIETVWGIGYKW
                     V"
     gene            31053..>31392
                     /locus_tag="KR294_001879"
     CDS             31053..>31392
                     /locus_tag="KR294_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3786 domain-containing protein"
                     /protein_id="HBH0239959.1"
                     /translation="MDEKITKNNYNVPFDYVRKKLKELDPHTISNLSNIPFNNDLNRF
                     TLNFFDRQYIIDYPSGEVWNSNGSLCNNFELKILIVRYLINAKGIPRTNKYVTFKEIP
                     GGNVYYPNFLN"
BASE COUNT         9540 a         5624 c         3388 g        12840 t
ORIGIN      
        1 ttgaataata ctctttggga aaagaattac ttgtatattc aatttatcat ttttagaatt
       61 tataacttta tattttattg aatagttatt tatgtttatt ggaatgtatt gtgttatttc
      121 aaattcaatc atgcttaata tgtctctttt tttcttagta tttagaactt caacatttct
      181 aatgactata tcctgaattt gaatgttaaa gtataaattt ttatataata tttttgattt
      241 accaatctcc tcttttacaa atctaactac atcttctata tatttaatct tctcaatcga
      301 attactatca ttttttatat caaagttaat ctcttttata attgatttat ctataaaaac
      361 ttttttatga ctttttctta aaaatacaag ccttatataa tcatcattta tttctaagtt
      421 tagaattttt ttaattatag ccatctcctt cttaaataaa aataatttta aaacttacag
      481 caatcaatat aaaatattat tttggataaa attgcttaga atttatattt acgcttatat
      541 ctgttccgct atcatttatg acaagttcga atttacctga tgtactctga ggaactggaa
      601 cagtatttag gtatcccttt tccttcaatg tctctacact tagagagtct attgtctttt
      661 catcatcatt aattgccatg ctagctgcgg ttactatatt agcagcattc gtatagtctg
      721 catttaattt ggcactttct tgaaccttac tatacttaac taatgctata ctagatataa
      781 cgcctaaaat agttactact acaatcattt caacaagtgt aaatcctttt cgttttttat
      841 ttatcaaatt tatcaattaa atattctctc cttttcaaaa gtttcatcta ataaaattta
      901 tttttctctc taaaaattag taattgcatc aaacatagga acaaccattg ctaaaataaa
      961 agtaccaata attaatccca taaatacaat tagcataggt tctataaatt tcattatttg
     1021 ctctattttg ttatttaatt cattttcata aaatttattt attacattta gacttttatc
     1081 tagtttccca ctttcttctc ctgtatttgc cattgaaata aataattttg gaaaaacatt
     1141 tgctaaattc aaagatttac ctatgctatt tccttttttt atataattat tggaaatctt
     1201 taacctttca taaataaatt cgttgtctat aacactagct gacatgtcta tagcttccac
     1261 aatttgtatt ccactgctaa ttaaaacgga caatgccctt gaaaatcttg ttgtagctac
     1321 taactgatta atttttttta taaaaggtat tttgaatttt aacgaattaa tcaatttttt
     1381 tatattatca tttgttataa agaaataaat gcttcctatt gaaaacaata taaaactaaa
     1441 tattatataa gctaagttat ttgtaaccac tgtagatatt cccattaaaa ctctagttat
     1501 taaaggtggt tcaattccat tgttggtaaa aaccacctga aaattaggta ttacaaatac
     1561 gaatataaac aacattgata agatagataa tattataagt attattggat atattgaaat
     1621 agttattatt ttcattttta atttgtattc tttatcataa taattagata aatcactcat
     1681 tattatatct aagtttccac tagtttctcc tgcttttatc atacttataa agaatttaga
     1741 aaatatacct gttatttgaa atgattctgc tattgagtta cctttttgaa tatgatttga
     1801 tactatacta agcaaattct ttgctttttt acttgactga ctctcaatga tttcaaatat
     1861 ttttgtaatt tcacatccag attccagcaa tatgcctatc tctttgcaaa ttactctaat
     1921 ttctttatca ctgattctat ttaatactaa ataaaacttt tctaaattat aaaatatatt
     1981 tttagataat ctcatgtact ataatacctt ccaaattata ttaattacaa ttaaataaac
     2041 ttaatatttt ctaatttaat gcatttaatt ttatttcact taaatataat ttatactcaa
     2101 acatcttaat taaaatagat taaataaaga caactgacca aacgaagttt aactatacaa
     2161 ttcagttaaa tcatttcatt tactactaaa cactcttcta atgtcgttat tttttcattt
     2221 attagtcttt tacaactatc ttcaaatgtt atcattccat tattttgtgc tacatcttta
     2281 atagtactag aatcctccat atttcttata catgtcttta tatcatcatt aatttctaag
     2341 atttcataaa ttgctgttct tccaaagtat cctttatcat tacatttttc acaccctaca
     2401 gctaccttag tatttacatc tccactaaaa ttatctttta tcataatctc atggctacaa
     2461 tgattgcaga cttttctaac caacttttga gatataacac ctataagaga agcatttaaa
     2521 agatatggtg gtatttgcat ttctagtaat ctagctatgg aagatactgc atcattagta
     2581 tgtaaagtac ttataactaa atgacctgtt atagctgctc ttactgctat cttagctgtt
     2641 tctgcatctc ttatttctcc gaccattatt atatctgggt cttgtcttaa tatcgctcta
     2701 agacctacat caaagctcaa ccctactttt gaatttactt gaatctgact tatgccatcc
     2761 atcttatact ctacaggatt ttctatagtc ataatatttt tatttattcc ttttaaatca
     2821 tttaataagg aatatactgt tgtagtcttt ccactacctg taggacctgt cactaataat
     2881 attcctgctc ttttatttat tatacgattt atagatttta tagcttcctc tgaaaaacca
     2941 agttctaatt tgtcttttaa aaaagtatct ctattaagta tcctcaaaac tattttttca
     3001 ccatagacag ttggtattga tgaaactcta atgtcaatta aatttccacc taactttata
     3061 tccaccctac catcctgagg aagccttttt tctgttatat ccattgatgc ctttaatttt
     3121 ataaccgtag acaatgatgg atagacatca actaaaaact ttgatacttc ctttagttct
     3181 ccatctaccc tcattctcac tattaaatgt tctttaaatg gttctatatg tatatcactt
     3241 gcgttttctt ttatagcttt ttctaaaaga ttttcaaata atttttttgc ataatcctca
     3301 tcaagttcaa agctattata atatttttca atcttttcac ttataagttc ttttttctcc
     3361 ttcttcaata taatttcttt acctgtagct aatctcaagt cctgtagagc ataaatatcc
     3421 tcatcttcta tttctacaac taaattatca tcttgaaact caactggaaa tacattatat
     3481 ttttttgcaa gtttttctgg tattaacatt ggcaaactgc tttcctctaa tataatctta
     3541 atcacccttt atatacttta atttattagg tatattcatt tttttcatag agatattttc
     3601 ttcagttttt atgcttattt tcattggata attggtttgt atgctatcta aatatttact
     3661 acctttatct acataattag atagtttctc cttatctcca atgcacttta tttcatatgg
     3721 ttgtgctaca ggaactccat ttatatttat atggcttcct gcaagtacaa cttctgaata
     3781 ttgattaatt ctttgaccat ttatttctat gtattttcct ccgtttactt ttaattcatt
     3841 tataactttt acaagaatct tattatagtc tatactatta gctatattcc ctgttttttc
     3901 atctatagca tctatactta atattatccc actacccttt acatctgaat atgatagact
     3961 atctctaagt gtttctattt ctgatatttc ttcagaattt ttttgatttt gtttcattga
     4021 attaatttct ttatctaact tgtctttctc tttggttaat tcttttatag attttcttgt
     4081 catttttatt tcttttctta ttgacttgtc tttgcttgta taaactgttt cttcattgct
     4141 ataatctcta aatatggttc caacaagtat acctaaaata gtacttgcta gtattataaa
     4201 cacatattgt tttttcatac tgtattgctc cttacaaatt tatttttata tgataatttt
     4261 ctttaattaa atattaaaca tttacatatg cttattatat caaagttata tattaaaatt
     4321 catctttagt atataatatc atacattgaa ctcctatcac taatttacca atatcaagta
     4381 tgcattttta gatgttctta aaattatata aactttcaat aaacattgtt ttgatattat
     4441 aaaaaaacat aaattaggaa aggaaataat aattatgaaa aacaaataat tgctttggag
     4501 attattaata tcatttttta gcaaaaaaaa gtaaaatggc atagcctcaa agctacacca
     4561 atttactaaa aattatatca ttattaacat taattttaaa catatacgtt tataagtttt
     4621 cctcatattt taaaattctt ttaattaatt tatctcttaa tttccctact tcatcaaatc
     4681 tcatattagg actatagtaa ctttctataa tatcatgttt agacttggct ctcttaagat
     4741 ttagtactgc ccaacaaatt aaatcatcta aaactttttc atcaaattta atatcttctt
     4801 catatttaag tagtttttct ctatttaaaa actgatttaa atcaattgta tcttcttctt
     4861 taaaagtcgt acttatagtt atgcctatat ctaaatcagt taatagtaca gtttcaattt
     4921 tctctggaat aagtggataa tgataaactt ctacatttaa acctttttca atagctttct
     4981 tatatacttt gtttaataat gtagttttcc cagttcctat ttctccatct aaataataga
     5041 ctttctttac atcttttaaa atgttttctg tataatctaa acaccctaca ggagttatag
     5101 ctgaaccaaa taaatgcttt tctcttttta gatttcctgt gcttttaact ccatcaaata
     5161 acctttttat aaattcttct gtgaccaaat ttactttgcc ataatccata caatcagaat
     5221 atttttcttc tatgtctcta aagattggtt ctgctgattt taaaaactta aatgctcttt
     5281 taaatgaatt actaatatct ttatcataaa ctgatatttc ttgtttattc ttttctaatt
     5341 cttctgtatt ccagtaatca cctaaattaa ttatctcatc caaagctcca ggtagctttg
     5401 ggtccatagt atgtggggca gttgcatcca taagtaccac gcctaatttc tttataacta
     5461 aaccatccaa cgaacttggg tcagaaggac aatgatataa atcaatatca tatcctctat
     5521 gcaaaaactc tttataaatt tttttcataa gtgaggattt tcctactcca ggtccaccct
     5581 ttaaacaaaa aactcttttt acattttcag gaattatata gtcaaaaaaa gaatatgagc
     5641 cttgtgatgt atttccaccc gggaatgcct tctttacctt tccttccata ttagcgcctc
     5701 ctcataattt acaatatctc ttaattaaga tattcatatt ataagaattt tattacagct
     5761 ttctgatttt gacaaattta aaacttgcca tctaatacta ataacaggtt aattttatct
     5821 aattattata gattctcata ctgtgcctta ttctatctat aaatacaatt taagtgtcca
     5881 tattgaaata tttgtattgt aatacagctg gatattactt aaatccaatt gtttccatta
     5941 taattttatg ttaaaataat attacaaaat acatctgttt ttcttcataa acgggtgaaa
     6001 ttacctatcg gcggtaaaag cccgcgagcc ttatggcata atttggtcat attccaaagc
     6061 cgacagtaaa atctggatgg tagaagaaaa tagtatatga gtacctttat gtaattttac
     6121 atgagtaatc tatacaaatc cttcaactac cgtatttatt catgaaatta gacacattca
     6181 aggtacctaa tatacaggtg ctttttttgt tgtttatttt acaattatat cgtacttata
     6241 aaatctatta agattggagt gttatcatga aacaaaaatg gatagtattg attatcatct
     6301 gtattggtgt atttatgtct actcttgatg gaagtatact aaatatcgca aatcctacaa
     6361 ttgctgctga ctttaaaatt aacatgtcac aaattcagtg ggttgtaaca gcttatatgc
     6421 ttgttgtaac agctactatg ttatttttcg gaaaacttgg cgataaagta ggttcaaatc
     6481 gtctatacac attaggattt tttatattta caataggttc ttttctgtgt agtatgtcaa
     6541 acaatttatc aacattaatt tcttcaagaa tctttcaggc agttggagca agtattttaa
     6601 tggctactgg gcttggtata gtttccaatg catttccagc aaatgaaaaa ggaaaagcta
     6661 taggaatcac tggagctgta gttggtatag gaaatatgag tggtcctgta attggaggta
     6721 taattttaga acattttgga tggccttcta tttttattat caatatccct attggtatta
     6781 tagcagtctt tcttggcatt aaatttctgc ctaaacctgt tttggatgaa caaaacaaga
     6841 gctttgatat tccaggtctt ctacttttcg catcttgcac tacgcttata ttacttgcaa
     6901 tgaatgagaa gggtaataca agattgtatt taggtataac agcacttata atcttcttat
     6961 tgttggcatt aagagaagta aaatttgaac aaagctttat tgacctccct ctatttaaaa
     7021 atagaaactt tactgtaggc aatatcattg gagtagcttg ttattttcct caaatggcag
     7081 tatcttttct acttccattt tatttagaac aattaaaaaa tttatctcct atgatggctg
     7141 gttatgtaat gactgtacat ccacttatta tggtacttat agcacctatt gcaggttcac
     7201 tttctgataa acacggtgca aaaaacattc taacagcatc tttttcattt atgaccatct
     7261 cactagttgg aatggcactt ttaaaagcag attctccatt gtacctttta attgtatgtt
     7321 tagttatttt tggacttggg ctaggagcat ttagttcacc aaacaatagt agtattttag
     7381 cagatgttcc tcctcaaaaa caggggtacg gaggcagttt tcttgcaact attcgtaatt
     7441 tatcatttgc tcttggaaca gcatttttta gtagtttttt tgcacaaagt cttacataca
     7501 atcaaaagtt taaaagtcac acatcagcct atgttatagc tagcaatcag tcttattgga
     7561 ttgcagcatc agtatgtttt gtagggctta tactaactgt tttctttatg aggaaaacag
     7621 ataaatctat ttcttaaatg ctatttatta ctgactacat aaatcaataa ttttttagtt
     7681 taactatttt atactaattt tcccatacct tactaaaatt tattagtatt tagcaaaatt
     7741 actgatattt attgtttata aacaataagg atgccaaaaa aaagttcatt aaaactattt
     7801 taaggcatcc tatattttac tttaatatta atataattaa aactaactat tattacattt
     7861 attattcaaa taaatcttat gtcaatattt aacattttaa atttaatcta ctgttatttc
     7921 atatccatgt tgattgtatt gatttacaat ctcttcccat aattcttcaa caccagtctt
     7981 ttttagtgaa gaaacaggaa ttactttttc actactttcc atttgcaatt tttttcttat
     8041 tatacttatg tgtttttgat attgtcctct agatatttta tctgccttag ttgcaataac
     8101 tacacagtta tatccaaagt gctttatcca ttcatacata agcttatcat ctgctgtagg
     8161 ctcatgtcta atatctacaa gtaggaatat agaacataac tcttgtctac tttctagata
     8221 tcgttccatt atacctcccc acttttcttt ttcagactta gctatctttg catatccata
     8281 gcctggaagg tctacaaaat aaaattcatt atttattaga taaaaattta tagttctagt
     8341 ttttcctggt gtttgactgg ttctagcaaa gtttcttctg ttaagcaatg tatttattat
     8401 tgatgatttt ccaacatttg acctaccagc caatgctatc tctgggattc cttctgctgg
     8461 atactgtgat ttattcacag cactcatagt tatctctgaa cttctaattt tcattatttt
     8521 caccactctt taataaagct tgttctaata cttcatccat atgttctaca agcacaaact
     8581 ccattttttc ttttacattt tctggtattt catctaaatc agcttcacat tctttaggaa
     8641 ttaatacttt tgttatacca gctctatgag ctgctaataa cttttcttta actcctccta
     8701 ctgctaagac tctacctctt aaagttatct ctcctgtcat tgctatattt ccaggcacag
     8761 gtcttttagt aagtgctgag attactgcaa gagccatagt tataccagct gatggtccat
     8821 cttttggaac agcaccttct ggaatgtgta tatgaatatc attcgtctta taaaattcag
     8881 ggtctatatc aaacttgtcc actattgacc ttatataaga gatacctgtc ttcgcagatt
     8941 ccttcataac atctcctaat tttccagtta atacaatttc gcctttacct ttaagtacgt
     9001 ttacttctac ttcaagtgta actccaccaa cttctgtcca cgcaagacca tttactaatc
     9061 ctatttgagg gttaacttct gcaagttgat acttaaacat gtcttttcca agatatgtct
     9121 ctaggtcaga cttatttata acaacctctt caagagttgg gtcttcaacg tattttttgg
     9181 caacctttct acaaatctta ccaatagttc tttctagtgt tcttacacca gcttctcttg
     9241 tataatggtt gattatactt cttaaagttt catcatctat ttttataaag ttttctttta
     9301 aagcatgttc tttaatttgt tttggaagta ggtatttttt tgctatattt aatttttctt
     9361 cttctatata tccagatact tctattactt ccattctatc taataatggt cttggtatat
     9421 tacttagact atttgctgtt gtaacaaata gtatttttga taaatcaaaa ggtatttcta
     9481 agtaatggtc cacaaaatcc ttattttgct ctgggtctaa tacttctagc attgctgaag
     9541 ctgggtcacc tttataatct gctgccatct tatctatctc atcaaataag aatacaggat
     9601 tttttgtttg ggcttctttt accccattaa ttattcttcc tggaattgaa cctacataag
     9661 ttcttctatg acctcttatt tctgcttcat ctctaactcc acccaaagat attcttacaa
     9721 attttctatt taatgctctg gcgattgatt ttactataga tgtctttcct gttcctggag
     9781 gaccaactag acatattata ggccctttaa gtgacttagc aagagttctt atagctagat
     9841 actctagtat tctctcctta actttttcta atccataatg gtcttcatct aatatatctt
     9901 ttgccttagt tatatctaat ttatcttttg tctctttatt ccatggcaat gagaatatag
     9961 tatctaaata gtttctactt acagatacat ctggagacat agaagatatt tttgaaaatt
    10021 tatctatctc tttttctatt ttctctttag ttgtcttagg tgcttttatt tttttaagct
    10081 tttctctata ctcatctgct tcagagttta tatcttcttc ttcacctaat tctttctgta
    10141 tagcttttaa ttgttctcta agataatatt ctttttgaac cttattcatc tgttttttta
    10201 ctcttaaagt tattttcttt tctattttta atatatctat ttcctctaat aatatagaat
    10261 aaataagttc aagtcttttt ctaatatcaa attcttctaa tatttcttgt ttttggcttg
    10321 attttagata tatgtttgca gctatcgtat ctataaatct atctacatct tctatatcag
    10381 ctaaagatat taatatttct ggtgataccc tatttccaat atttatatac tcttcaaagg
    10441 catcaaatac atttcttaca aatgcttcaa tttcaacttc tgtttcacta tccaaattat
    10501 cactatcaaa tactatttct tctattactg ctctgaaata cccatcttct tgttctattt
    10561 tctttactct accccttgat acaccttcaa ccaaaacacg aactgtatct cctggtaatt
    10621 ttatcatttg cttaacttta cagattgttc ccacatgata aaaatcctct tctcctggct
    10681 catctacctc tgcttctttc tgagaagtta aaaatataag ttcttcatcc atcatagctt
    10741 ggtctaaagc tttaagagat atctctctac ctatatcaaa atttaatatc atatatggaa
    10801 atatagctaa tcctcttaga ggaattaatg gtaattcatg atctatttta gtataatttt
    10861 gttccatcaa cattactcct tttctagtct aattgctttg cttttaatat tatatatttg
    10921 aacaagttaa ttttcaacat taatgataaa ttcttagaat actatcatac tatattatct
    10981 ttttattatg atataatatt aatattagta tacttagatg ttatttatct tttggaggtt
    11041 tctattatgt tgaaattgtt tttaaccttt ttaaaaattg gtgcgtttac atttggtggt
    11101 ggatacgcta tggttcctct tatacaagat gaacttgtaa acaaacaaaa acttttagag
    11161 caggaagaat ttattgatta tttatccata gctcaaagtt atcctggagt actggcagtt
    11221 aatatatctg tattattagg atataaactt tatggtatac caggagttct tatatgtacc
    11281 ttaggctctg ctttaccatc attttgtata gtcttagtct tatcgtatct atactttaaa
    11341 aattcatcat ctaaaatttt agatggattt tttaaaggag ttgcgcctgt tgtaatagct
    11401 cttatattgt attcttttac gagcatgttc aagaaactac caaagtctaa aactaacata
    11461 ctactattaa ttatagcagt tttatctgtt ggtgtattca atataagccc tatttattta
    11521 ataattggag gaggtgtata tagtctatgt cagaaataat actactcttc ttaatattcc
    11581 ttaaaatagg ggcatttagt tttggtggcg gttatgccat gctaccattt atccagcaag
    11641 aatttatatc taaatatcac tttataacta atcaagagtt tttggattta cttgctatat
    11701 cacaatctac accaggtcct gtagcaataa atagtgctac atttgtagga tttaagactg
    11761 ctggcttctt tggttctcta gccgcaacta ttggtgttac aatttttgca ttaataggtc
    11821 taactattat atcaaagtta ttttctaaat ttaaaaataa taaaaaggta gaaaacttat
    11881 tgacagttct tagaccaatt actctaggat tcatattatc agcagctttt tcatctgcca
    11941 aagaagttaa ttgggattta tatggaataa ttgcatttat agcatcattt tatcttttat
    12001 ataaaggaaa aattggttcc attgcaattg tattcgtctt tggtattcta ggtatattac
    12061 tcacattttt ataataatga tacctatttt atatttagca tattaacata aaaaaaggag
    12121 cttttaaagc tccttttcat catcttatgc actttcctct tgatccttaa gtactatgat
    12181 aggatttact gagtcttcgt tcacagattt ctctgttact ataaccttct ttatattatc
    12241 tctagatggt acttcaaaca tagtttccat cattacgctt tcaactatac ttctaagtcc
    12301 tctagctcct gtatttcttt ctatggcctt tttagcgatt gcacgaagag caccttcttc
    12361 aaattctagc tcaacatcat ctaactccaa taacttttta tactgtttta ctagagcatt
    12421 tttaggttcc tgtaatatct gcattaatgc atcttcatcc aacaactcta aagtagctaa
    12481 aactggtatt cttcctataa actctggtat tataccatat tttaataaat cctctggaag
    12541 tactttttca tatagcttcc ctaaatctaa ttctttttta ctttctattt tagctccaaa
    12601 acctagtgtt ttatctccac cacgtttttg aattatcttc tctaatccat caaaagctcc
    12661 acctaatata aataatacat tagtagtatc tatctttaaa aattcttgat gaggatgttt
    12721 tcttcctcct tgtggtggaa catttgcaac agtaccttct aatattttta gaagtgcttg
    12781 ttgaacacct tcaccactaa catctctagt tatagatggg ttttcagatt ttcttgcaat
    12841 cttatctatc tcatctatat atattatacc tctttcagct ttttctatat caaaatcagc
    12901 agcttgaata agttttaaaa gtatattttc aacgtcttct ccaacatatc cagcttcagt
    12961 caatgatgta gcatctgcca ttgcaaaagg tacatttaga gttcttgcta gagtttgagc
    13021 aagtaatgtc tttccagaac ctgtaggtcc taataaaagt atattactct tttgaatttc
    13081 tatatcctta ctactagatt ttttactgta tattctctta taatgattat aaaccgcaac
    13141 tgataaagct tttttagctt tttcttgacc tattacataa tcatttagaa tctccatcat
    13201 ttcctttggt tttggtaaag atgtagtatc ctcatctata gtatcttcta tctcttcttg
    13261 aataatttcg tcacaaagtt caacacactc gtcacaaata tatacatttg gacctgcaat
    13321 taatcttctt acttgatctt gatttttacc gcagaatgaa cactttaatt gtcgtttttc
    13381 ttcatattta gacatattaa cacctctctc tatctacggt ctctttgtaa atacttcatc
    13441 tattaaacca tattctttgg cttctagtgc actcatgaag ttatcacgtt cagtatccat
    13501 tttaattttt tctaatggct gaccagttct ttcagataat atctcattta aagtttcttt
    13561 tatttttaaa attctctttg catgaatttc tatatctgtt gcttgacctt gagctccacc
    13621 taatggttga tgtatcatta tttcactatt tggtagtgct agtctttttc cttttgctcc
    13681 tgctgccaac aagaatgctc ccatagaagc agccatacct atacatatag tacttacatc
    13741 tggtttgatg tattgcatag tatcatatat agccattcca gaagttatac ttcctcctgg
    13801 agaatttata tataaatgta tatctttgtc tgggtcttca gcttctaaaa ataatagctg
    13861 tgctactata agccctgctg tggcatcgtt aacttgatct cctaagaaga ttattctgtc
    13921 ttttaatagt ctagaaaaaa tatcataaga tctttctcct cttcctgttt gttcaacaac
    13981 tacaggtact aatgccatgg tttcataccc cctttattct atataattta cagtagcttt
    14041 ttttaagcta ctgtaaatta ttatacgcat ttaactaaat tatatttgca catcattata
    14101 tactaaacat ttcataacgt caactatatt agttagcgtt tattttatta agctattgtt
    14161 gcattatcaa ctaataaatc tattgttttt cttattttta tttgaccttt tatatcttct
    14221 ttgtcggcat ctcttaaaga agcttctatt ttttctactt ccatattgta agcagaagcc
    14281 attttttcta actcagcctt aaattcttct tctgttgctt caattccttc agctttagtt
    14341 attgcttcta atactaaaga agacttaact aattttttag catcttcttt tctctcttct
    14401 cttaattctt ccatagttct accagtcatc tctagtaatt gttgtaatcc aaatccttga
    14461 tattgtaatt ggtagttaag ttcatttaac atattatcta tttgatgttg tatcataact
    14521 tctggtattt ctatttctgt attttcagca actttttcta ctactgaatt tctagtttct
    14581 gcatctgctc tatttttagc ttcttcttct aacttagctc ttacatctgc ttttaattca
    14641 tctaaagaat caaattcact agtatcttta gcaaattcat catcaagtgc agataattct
    14701 tttactttta catcatttat ttttacatta aatacaactg gttttccagc taaatcttgt
    14761 gagtgatatt cttctgggaa agtaacatta acttctactt cttcaccagc ttttttacct
    14821 actaattgtt cttcaaatcc tggtataaat gtgtttgaac ctataactaa gttataattt
    14881 tcacctttac caccatcaaa agctacacca ttttcaaaac cttcgaagtc tattatagct
    14941 gtatctccat cttctaaagc tttgtcttct acacttacta atctggcatt tttttcaacc
    15001 atttcttgta gtttagcatc aacattttcg tcacttacag tattctcaac cttagctatt
    15061 tctataccct tgtagtttcc taattcaaac tctggtttaa cttctacatt aagaaccata
    15121 accaacccat tgtctttact tatttcttct atatctaaat ctggattgtc tattgggtct
    15181 atgtctaatt ccttgatagc ttctggataa acttctggga ataatatttc tatagcatca
    15241 ttgtagaata taccttttcc gtattgagtc tctataacaa ttcttggagc tttacctttt
    15301 ctaaatccag gtatattgta tttatttctg cttttattat aagccttatt tactgctgct
    15361 tcaaatttat tgttatctac tgttattttt aaagtaactt tattaccctc ttttttaatt
    15421 agttctgctt tcatccttct aatcctccta gtgatattta tgtaataccc gataacggta
    15481 ttataattca ttctatttat aattcaacca cttaattata tcacataagt ttttttattt
    15541 acaagtgttc cattaatatc gttgtactta tttgataaaa tttaattttt tgagcgtttt
    15601 ttgccatttt tttagataaa tacaccttta tatgcgtatt tcttcaattt ttatgtcatc
    15661 ttcttctata tccataatga caaaactttt atacgatact cctcttggaa gtgaagtgct
    15721 tccaggattt atgtaaagta caccatcttt aatttctcta aatggggtat gggtatggcc
    15781 aaatataact atatcagcat caacttcagt tgcctttttt tctaacatat gagttccata
    15841 ttttacgcca tacttatctc catggcataa gaatatggtt ttatttgcca cttcaaagac
    15901 aacttcttcc tcaacagcat caaagtcaca attaccttta actgcaataa tacctacatt
    15961 agtcatgcta tgaatatatc ttgaatcagt aaagttatct cctgcatgaa ttattaggtc
    16021 acattctttc aaatatggta ttgttttttc catattttta atcatcatat gtgtgtcgct
    16081 tactatgcct attttcatta cttcactacc ctttttataa actcttgttt cataagtttt
    16141 agtgcgtttg ctctatgact gattgaattt tttataacac taggtatttc accaaaagtc
    16201 ttatcatatc cttttactat aaataagcta tcatatccaa aaccattttt acctttttct
    16261 tcaaatccta tcattccttc acaaattcct cttactacaa attcttttcc atcaggaaaa
    16321 actactgcta ttgcagagac gaatcttgca tttcttttgc tcattggtat attttgcata
    16381 gcttttaaca gtttttttct attttcttca tctgttgcat gttctcctgc atatctagct
    16441 gaataaacac caggtttttt gcctaaagca tctacttcta agccagaatc atctgatatt
    16501 gctataagtt tagtcttttt tgctattgtt ctagctttta tcaacgcatt atgctcaaat
    16561 gtttttccat cttctactat ctctatacct gctaaatcaa catcttttaa agagtacact
    16621 ttatattcaa aatcttttaa gatttcacct atttcttcta gcttatgagc attattagta
    16681 gcaatcacta cttcattacc ataatccata cccaatatct catctgatat ttcacctaaa
    16741 gcttctcttt gaagccttat taattcttta ttcccttttt cacctaactc taacaataaa
    16801 tttaaatctg ctctcgaaaa aggtttctct tctcctgtcc cctgtacttc tacaaactca
    16861 cacttatcag tcattattat attcatatct acctgtgctt tagaatcttc ttcataacat
    16921 aaatctagca tgtgtattcc atttacaata ccaacactaa ttgcagacac aaaatttgtt
    16981 attggcatct cttttattat ctttgcttta tataatttat atattgcttc tgcaactgct
    17041 acaaatgccc ctgttataga tgcagttcta gttccaccat ctgcctgaat cacatcacaa
    17101 tctacccaaa tagttctttc tcctaattta ttcaagtcta caacagacct tattgctctt
    17161 cctattaacc tctgtatttc ttgtgttctt ccatcaattt ttcccctaga tgcatctctt
    17221 atctttcttt gttgtgttgc tcttggtagc atagaatatt cagcatttat ccatccagta
    17281 ccactatttc ttaaaaaagg aggaactttt tcttccactg atgcagtgca tataaccttt
    17341 gtctctccca tttctataag aacagaacct tctgcatact ttgtataatc tctagttatc
    17401 tttacaggtc ttatctgttc gttacttcta tcataacttc tggtcatttt ttatatcctt
    17461 tctcatattt tttatttttt ataaatttat ttttataatt tttaattttg tcaaatatta
    17521 attattgtca tttttcgtaa tcttattagc ttactgaact attctatcat taattatagt
    17581 agttttctac taaattaagc gactttttaa ctctctaata cagcttttac ttcatctttc
    17641 gatgataact ttaataattc taaaaatctc tcttcatcta taactttaat tcctaaatca
    17701 tttgctttag taagtttaga accagcttct tcacctgcca aaacaaatgt tgtcgattta
    17761 ctaacactag atgtagcttt tccacctctt ttttctatca tatcttttgc atcatttctt
    17821 tttaatgtag gaagtgtacc agtcaatacg attttcatcc cttcaaatat tttttctact
    17881 ttttcacctg tattatccaa tgattttgta tttactccta cattttttaa cttgtttata
    17941 acgttcatat ttttgtcttc cttaaaaaac tcgacaacgc tgtttgccat tatacttcca
    18001 aattcctcta attcttctag ttgctcacta gttgcagaaa ttacttcatc taaatcctta
    18061 aagttatatg caagtatctt agctgcttta actcctataa atttaatacc taatccattt
    18121 ataagtctcc ataaatcatt ttcttttgat ttttcaattg aatttattaa attgtcagca
    18181 gatttttcgc ccattctctc taggtcgact acatcttcct tttttatata atataaatca
    18241 gatacatctt gaataatttt ttcatttaat agcagtgtaa ttatagattc tcccaatcca
    18301 tctatattca ttgcatccct tgacacaaag tgtataattc cccttcttat ttgggctggg
    18361 caagacatat tgatacattt tacagcagct tctccttcta atcttattgt tggctctgaa
    18421 caaactggac acttttctgg cattttaaaa tctatttcat ctccagtacg ttcttctttt
    18481 ataacttcta aaacttgagg tattatgtcc cctgcttttt gaactaatac tgtatcattt
    18541 atttttatat ctttttctct tatataatct tcattgtgaa gtgtagctct acttacagta
    18601 gtacctgcaa gtctgactgg ttcaagaatt gctgaaggtg ttattgtacc agttctccca
    18661 acttctacta ttatatctac tattttagtt ttcttctttt ctgctgggaa tttatatgca
    18721 attgcccatc taggactttt ggctgtatat cccatttcgt ctctttgttt tatattgttt
    18781 acttttatta ccataccatc tatttcgtag tctaaattac ccctgttatc tgtccagtat
    18841 tcaatatgct caataacttc atctatactt ttacaaactt tataactctg acttactgaa
    18901 aatcctagtt tttctaagta ctctagtgat tcactgtgac tttctaaatc gtattcttct
    18961 atattttcca tattaaatac aaatatatct aatggtctct ttgctgttag ttttgggtct
    19021 aattgtctca atgaaccagc tgcaagattc cttggattag caaataatgg ctgttcttgt
    19081 tcttcttgtt gttcatttac ttttctaaaa ttatcttttg atatatatac ttctcctcta
    19141 actattagtt cttttttatc atttatctta agaggtatgc tttttactgt cattaagttt
    19201 tgagaaatat cttctcctac aactccatct cctctagttg ctcctttttc aaactctcca
    19261 ttgttataag ttagacctac agaaagacca tctattttaa attcaacaac atattcaaca
    19321 ttttctccca catattcttg aactctctta tcaaaatctc tcaaatcttg ctctgaaaaa
    19381 gcatttgata aactcaacat aggagtttta tgtacaattt gattgaactt atctaatggc
    19441 ttacctccta ccctatttgt tggagaatca attctcttta gttctggatg ttcttcttct
    19501 aaagaaatta actccttcat taacttatcg tattcataat ctgatatttc tgggctatct
    19561 tgattataat acctttcatt atggtagttt attgtctcta taagtttatt aatttcatct
    19621 tttacgctca ctttttgcac ctcttcatat ttttaaaatt aaattatttt gaaatttccc
    19681 tataattaat tatctcctat ttatatattt tttagtatat cactttttgg gctttaaatt
    19741 tattacaaaa aaaactctta ttagtatctt taatacgact aataagagtt tttattttta
    19801 tcaaaatttt ttatttttaa tagcctcttg atatgtctac aacattatct acaggtttat
    19861 tctccattat atagtgtttc aaattattat aaaccatatt aaatgttctc tctttgtttt
    19921 tatctgacac ccaagaatta tgaggagtta ctatgacatt ttcgcactcc cacaacttat
    19981 tgtccttgtt taaaggttca ctttcaaata cgtctaatgc tacccctcta aatttctcta
    20041 cacattcttc taaatctttc tgattaactg tatttcctct acctacattt ataaatacag
    20101 aaccatcttt cataagttta aacatatctt tgtttactat tccatctgta ctttttgtag
    20161 aaggcattgc tacaactact atatcacatt cttcaaatac aatattcata tcttcagtag
    20221 caaaacactt atcaaagtat tttttactac ttccatcagt attgacaccc catatttcta
    20281 caccaaaagc ttttaatctt tttgctgctt ctgaagatat agtacctgtt cctaaaaatc
    20341 caactctttg tccatacaat tctgatacag aaaaatccat cttccattct ttattttgtt
    20401 gttgtttaaa aaattttgca ctatttttat atatttctaa aatatacaat acaatacttt
    20461 caccaatagg tacactatat ccgcctctat tattagctat cttaatattt ctcttcaata
    20521 cctcttcttt tggaagttgg tctataccta cactagttgt ctgtatatat tgtaaatttt
    20581 tcatcttaga aatatctaat ctctcaaatg gattgtatgt aactagtaca tctgctgtat
    20641 ttacatcctc attattttca atactatctt cagagtaatg tatgacatca tagcctaatt
    20701 ctcttatttt atcaaatttt tcttttccat aatttattgt aaataaaact ttcatctcaa
    20761 atctcctcca tctacccaca tttaaaattt tatattctaa aatataatat gatactcaat
    20821 gtacattagt taaaattact ataagatatc ttaaatttac ttatgttcaa ttgtttttcc
    20881 taaagacata gcattacgtt cttgaactaa attttctatt aaattattca atgtccaatc
    20941 aatagatgtc tctgttacca tagctgtaaa aggtctattt attctcactt tttttagccc
    21001 ttctaaaaat gcatttactt gtgtgcttgg agtgttatta aatattacag acttactctt
    21061 aatcccattt tcacattcat ttgatatatt tccatctaaa atgtctctta ttatattctc
    21121 tccattttta tcacttaaga tgatatggtc tcttattcca gcaaagttac ttacgttttt
    21181 aattaatgat aattcttttt tattaaagtt tacaagcata atacacttcc tgttgtgtat
    21241 tttatctagg ttattattat ttattttttc aaatgacatt ttatccatcc tttcatttat
    21301 ttatatactt taatttaccc catacattta aaataatcaa tttttatagt taatttttat
    21361 attaataccc aaattatatt taaatagttg ggctatccaa aactaatata taaaattaga
    21421 ataattagat taatatctac aaatcataac ctaaaggaga gataccatga atacattact
    21481 aaacaataaa tttagcatta aaaacttttc aaatgcttgg gttatagtac ttggttgtat
    21541 gttgatacaa gctgttccat ttagtattgt agcaagtata cagcctcaat ttataagtta
    21601 tgttgtagaa ggagaaggct ttagtttagc ttctttttct ctaatattca ctattggtac
    21661 tattgcctca gcaattgcat caccttttat aggtgtatta ttttctaaag tcaatattaa
    21721 gatactatat ttattaggtt gtataatttc tagtattgct tttgctactt tttctatatg
    21781 tactgaacta tggcaatttt acactgtatc atgtattgtt caaattggcg ctacaattat
    21841 atctgctata ggaatacctg ttttaataag tgcttggttt gatgaagaaa gcaaaggaaa
    21901 agctttgggc tttgcttttg ctggtggttc tattggtagt atatttctac aaccacttgc
    21961 agttcgctta ttagcaactc aaggatacag tcgttcttat ctaatatttg gaattatagc
    22021 attaatagtt ggtatacctg taatattatt catactcagg atgcctaaag atattaatga
    22081 aaaggtaaaa tctaaaggta aaaaagagaa agcatctgat acaatttctc cttcagtatg
    22141 gggttataca ttaaaagaag ctaaaaaaat taaatatttt tggattatga ctattggatt
    22201 tatatttgtt ggtatatatg tttcatcatt atccgtacaa tatccaactt atcttagaaa
    22261 ttatctaaat cctattctaa taggaacagt aggctccaca tttgctttat ttgctctcat
    22321 tggtaattta tttggaggat tattgtttga taaattcggt caaacaaagc cacttattat
    22381 atcttttgta ttggttctta tagcaacttt atcattacta ttggtagata aatcttctac
    22441 ttttgcattt gtatttgcca ttttgaaagg tctttctgta tttgcttata tgattggtcc
    22501 tgcttattta actggctctt tctttggtca aaaggagttt ggtagcatat atggaatcgt
    22561 acaattaatt tttgcagtgg gatttgcatt aggttcaaca ttatttggat tgttagttga
    22621 taattttgga tacagatttt cttggtctat tataatttta tcagttataa ttgcctatac
    22681 tttacttatt ataacttcta taggaatgaa aaaattgaat aaagaaagat tagataaact
    22741 aatgcaataa ttgattttta gatatataaa tattataata aaaaagatgg agcttttaat
    22801 cataaataaa actccatctt ttttatatta caatatagct aattttctct tatttttaac
    22861 tttactatct atatcctcat ccttaactat agtaaatgcc ttagttggac aaacatttac
    22921 acatgcaggc ccttctggcg attctataca aaaatcacac ttatttgctg tcattctttc
    22981 tctaaagcaa agctttcctt catctacatc ttttaatgta actatgtcta ttgcacctat
    23041 aggacatgct aacatacaag tcttacatcc tatacaattt tcttcattta tttttattgt
    23101 gttcccaacc ctaactatac caccatttgg acatgccttt gcacaaggag catcttcaca
    23161 atgtctacac tgtattggag cacttacttc ttttgtcttt atgacagaaa gttttggatt
    23221 aaaatttatt tcatctagat tttggtaaaa aatatcttca tctgaatgtg caactacaca
    23281 tcctatcata caagttctac atcctatgca tttatcaggg tctgctataa caaaatagtt
    23341 catcacttag ccacttcctt tcctatacaa tatgtagtgt gtaatagatg atgagatttt
    23401 tctcctaatg gttctaccag atattcatca tacagttttt taatatcagg attctcatga
    23461 gattttctaa ttgctaaatg ttcatcatgc acgtatgttg cttttgttct attttcataa
    23521 gccaattcct tatattcttc tagtaaaatt tttggttgac ctccaccact tacacaccca
    23581 acaggacaag tcataacttc aataaaatct acatctaatt ttcctttttc caagtcttca
    23641 agcactggta ttacattttt taatccactt actactccaa ctcttaagtc taagtctcct
    23701 attttaatag ttgactttct aaaaccattt tctcctctta cttgttttac ttctacatca
    23761 ggaatacttt ctccagttat aagctcatat cctgttctta tagcagcttc cataacccca
    23821 ccagtaacac caaagatagt tccagctcca ctataactac ctaaaggact atcaaatttt
    23881 tcttctctta aatttttaaa atcaattccc atgtctttta ttaaataagc tagttctcta
    23941 gtagttaata ctacatctac atctctatat ccactagaat ccatttcttc tctatcacat
    24001 tcatattttt tacatgtaca tggcattata gaaacactaa atatctttga tgcatctaca
    24061 ttatttatct ctgcaccata agttttaaat attgcaccac ccatctgctg aggtgattta
    24121 caagaagata aatgattagt taatttagga taattttttt ccatgaattt tacccaagct
    24181 ggacaacaag atgtaaacat tggaagagtt ccaccttctg tcactctttt aattaattca
    24241 ctaccttctt ccattatagt taaatctgct gcaaaattag tatcgtagac tctatcaaaa
    24301 tttaaagctc taagtgctgc tgccattttc ccagcaccta agtatcctaa ataatatccg
    24361 aaatcttctc ctaaagcaac tctaactgct ggtgcacatt ggaccatagt gaatacattt
    24421 gggtcactta aagctttctt caccttatct atatcacata cattgtatgc tgcaaatata
    24481 ggttcattta tagactctgg tatctctctt tcttgttttt tctcttgtaa aaactcaaat
    24541 ccttcatcta taactgaagc ataagattta caagtttgaa cacattgacc gcacataaca
    24601 catctatcta aatttatctc ttgtggcttt ccctcttcac cttcaatagc atttactgga
    24661 cagacctttg aacattctct acatccagta cataaatcct tatctatatt tattatcata
    24721 aacgtcacct acccctgtat cctttattta tttgttaaca ataaactaag tgcagcttgt
    24781 ctattcttag cttttttgtc atctattgga gtaacaagtt ttaatgcttc ctgaggacat
    24841 gcacttatac aagctatttt ttcattgtct ttacataagt cacatttata agctatcttc
    24901 ttattttcat ctaaaattac ttgttctact tctttaccat cttcatattg tggaagtaag
    24961 tctatagctc caaaaggaca tgctagcaga caagttttac atcctataca cttttcttca
    25021 tttacagaca taatattgtt ttctttaact atagcttttt gtggacatga gtttaaacaa
    25081 ggagcatctt cacactgtct acactgtatt ggcatacaga aattgtcacc ttttactaag
    25141 taaagtctag gtataacagg tatatcaact gttccaactg tataacccac attattatgc
    25201 tgattatgca ttgtaaaaca agctacttca caagctctac aacctgtaca tttgtttggg
    25261 tctgctatta caaaagagcc tattttattt ttcatattat cccacctttc aatttgtata
    25321 tttccaaccc tctagttatt ttcatcatat gtctacttac tttcatcata tatatttata
    25381 tatttcacta ttttctcagt acttatattt cgtttacatt ttttgcacaa attgtatgtg
    25441 ttattataca ccttatcagt atcatcaatt aatactccac agatttcaca ctttgaatat
    25501 ctttgctctt cttttttagt acacatatat tcattctcac tttttgataa ctctctgtgg
    25561 atttgcataa atattcatcc gtcttcctct tacaaatcca ataagcgtta tatttaattt
    25621 tttagaaagc tctattgata aattagtcgg tgctgatttt gatactacaa taggaatttg
    25681 agtcatagct gcttttaata tcatttccaa tgatattctt ccacttacag ccacaatttt
    25741 atcttttaat gttatgtcat ttaaaacaca aaatccaata gccttatcca ttgcattatg
    25801 ccttgctaca tcttcacaag tgactatttt tttatcaaaa ttaaatacag atacgctatg
    25861 taccccacca gtatttttaa ataattctga tgaatttaaa tttctatcca ttatactgta
    25921 aatcgtatca taatttattt ttatattgct ctttacagga gcacatgtta tatagtctag
    25981 tgaatttaaa aatataattt gctcatcttg atttttttgt ttctcttgaa tagttacttt
    26041 tgcaaaacgt tcactctcat ttatctcaaa ttttaataag ctttttttgt tttctatgta
    26101 tccttttgtt ttcaagaatc ctactataag ttcctctaaa ttatatgggg tacataaaaa
    26161 tgtatttata tatttatcat ttaaaataaa actaagtgga tattctgcaa ttatttcttc
    26221 attatctatt gatacttcat gttcatttat tttgcttact tctacattaa aagaatttaa
    26281 atatttgtag tccactagac tataactatt ttcaaaaact ttatccttac tattttcttg
    26341 taatttagtt tttgagtata tattgttcat aaaatattag cctttctgcc ttttataaat
    26401 cttaaatcta ataaatcatt agatatttgt agctgtcatt ttgtctttca aactttgata
    26461 ctcttctctt acacattttt ctgctaattc ttggtcttca agtttttcaa gtttaacagc
    26521 acaatattta tactctggtg ttttagatat aggatctaaa tttgctattg taagttcatt
    26581 gcaagctcca acccaccact gataagtcat atatgttgca ccttccttaa ctctatcagt
    26641 aactgttgct cttgttatta cacttcctct tcttgaacta attctaacta attcatcatc
    26701 ttcaattcct aatttttcag catcattaga atttatttga acacgtcctg gttcatcttc
    26761 taatgaacta agtgttctac aattaccagt cattgttctt actgaatagt gtccaacttc
    26821 tcttacagta cataaactaa atgggtattc atcatcttca acttccatag ggggtctcca
    26881 ttcagcagcg aacaaattac ctttaccatt aggagtagaa aacttttgac cttcatacag
    26941 atacatagtt cctttatctt ccatactttc actcttacaa ggccattgaa cgcatccttg
    27001 agtttctatc ttttcataag tagcacctaa gaaacttgga cataattgtc taagttcgtc
    27061 ccatatttcc ttagtatttt tataattcat aggatatccc attgctgtag aaatttcgct
    27121 tataatttgc cagtctggtt ttacatctcc ttgtggctct atagcttttc tcatcaattg
    27181 gaatcctcta tctgcacatg tatatactcc ctcatgttct ccccaagaag tagctggaag
    27241 tataacatca gcgtgaagtg ctgtcttatt cataaatata tcttgaacaa tgacaaattc
    27301 caattcatct aatgcttctc taacttctga tgcatctggg tcactttgca ctgggtcttc
    27361 tccaaatata taataagctt taagcttttt ctcttttagt actaaatttg gaacttgagt
    27421 taaactataa ccattattag gagataattt taccccccaa gctttttcaa acttttctct
    27481 tatcttatca tcagttacat tttgatagcc aggatataca ttaggaagag ctcccatatc
    27541 acaagctcct tgaacattat tttgtccacg tacaggtcct attccaacgc tttctctacc
    27601 aaaattacct gtaagtagag caattgatgc aagtccctta actacatcaa cagcttgacc
    27661 aaattgacag acacccattc cataaagtat catagctttt ttaccttttg catattctct
    27721 catagctttt cttataagct cttctgggat tcctgtaatc ttttcagcat atttagctgt
    27781 atatggttta acaatttctt tatactcatc aaatccttgt gtatgatttt gaacaaattc
    27841 tttattgtaa agaccttctt ctattaatac atttccaaaa gcatttacta aaaccatgtt
    27901 tgttccacct tttataggta gatgtatatc agcaattctt gcagattcag ttactctagg
    27961 gtcagtaaca attaatttag caccattttt tttagctttt actattctat ttgccactat
    28021 tggatgtgaa tctgctccat tatatccaaa tataaataaa acatctgcat tttctatctc
    28081 tggtatagaa ttagacattg caccactacc taatgagtaa gccagaccgg ctacagatgg
    28141 tgcatgtcag acacgagcac aatggtcaac attattagtt cctattgtag ctctcataaa
    28201 tttttgcatt atatagtttg cttcattacc aggtcctctt gcagaacctg ttcccataat
    28261 agaatcagga ccatattttt ctttaatttc atttagtctt gaagctgtat agtttatagc
    28321 ctcatcccat tcaacctctt ctagtacacc ttgttttctt atcattggct tttttagcct
    28381 aggtgttaga attttagggt catttagaaa atcccatcca taacgacctt ttaaacacaa
    28441 actttcttga tttgttctac cattagccgg ttcagctctt aatatcttat tatcttttac
    28501 tactagatat aattggcatc cagctccaca gtatggacaa actgttaaaa tttttttctc
    28561 catacaattc cccccttaga tttatcccct gataagtaaa atttatctta aagataatga
    28621 gtgtttttat aatatgcaaa atcataaata ttttgcaata ctatctatta aattcaacaa
    28681 ttttctcaca attcctctta aatttcaaaa aaaatatgtc ataataatct ttatatttca
    28741 accatttaat taaaatattc tagttcttat gacatatttt ttaatatact caatatatat
    28801 tctttaaact tatttagttt tcacttaaaa caatatttct gccaattcta tttttcattc
    28861 tatagtgagt aattacagta aatattccac ttccaatcag aatcaaatag tacataaatc
    28921 caccatataa aaatactgca tatcccatca aaggttgagg gaatactgat ttgaatatag
    28981 tgaaaaaggc taattcatta gctcctacat tcccaggtgt tggtattgga gatattgcca
    29041 tatataaaaa tgcttgtaat gtcagtatat aaatatagct ataaccttgt aaattaaatg
    29101 ctttatatat ccaaaatgaa acactaaagt aagcacttaa ttgaataaaa gttactatta
    29161 tagttgaaat taataccttt ttattctttg caaaaaaatt tattgcttta ctataatcat
    29221 ctataaaact ttctatggat tcaatcttat tatctaaaaa ttttaaaaac ttaatttttg
    29281 ataaatgctt tatagtaatt ctcataaaat attttatttt tttaggattt aaaataacta
    29341 atattatcat aattaagaca aatgaattaa tggctatccc tagaaacact agaggcataa
    29401 tcattttcat ttgtttttct aacatagcaa aattcattaa aacaagtatt gtacaataaa
    29461 aagtaactac tatttggaag ataatagact tattggtaac aactgcactt gccttactaa
    29521 gtggcatttt acatttttta agtacatata tctgtactgg ttggcttcct gaagcaaaag
    29581 gagttattaa attataataa aatcccataa tggctagctt aaaaccaata aatctaatat
    29641 taactttgtg agtgctttct ataattatct tcattactac tccttcaagc attatgtgac
    29701 acattattgc caaagcacct atgaataaaa acttcttatc taccataacc ataacatttg
    29761 atagcatttt aatatccaat gttttaaaca ctaggtaaat tgttatacct attaacaaaa
    29821 ataaaaatgt atactgtagt aaactctttc taatattctt tagtctatcc attagaaata
    29881 accatccttt gctcaagatt tatactaaat actatattat tagtatacac tatgaatctt
    29941 aatattttat aacaaaatac cttacaattt tgtcatttac aaaaaatatt aatctataaa
    30001 ttaaatttta atatatagat taatatttta caaacatttt gtagatatat ataatatttt
    30061 cactaaacaa cacttatact tattacaccc atttataccc tatcccccat acagtttcta
    30121 ttgtataaat atcatattgt tttaatttgc ttcgtatatt ttttatatgc tctgtgatag
    30181 tacttatatc actttctcca tcaaaaccat ataccgactc atatattctt tcttttgaaa
    30241 atacttgtcc cttatttttt gctagaaatt cacatattag atattcactt ttagtaaaat
    30301 taattttttt accatcaatt gaaacttctt tgcctaaaaa gttaaattga acatttgaga
    30361 tagttaataa attctttttt tctctacttt ctcgccttaa atgagcagtt atcctagccc
    30421 ttaattctcc tacaccaaaa ggtttggtta tatagtcatc tgcacctata ccaagaccgt
    30481 acataatatc actttccata ttttttgctg tcaaaaacag tattggacaa tcaaccttat
    30541 ttcttatagt tttacatact tcaaaaccat ccatcttagg catcataaca tctaatatta
    30601 ttagattaaa ataattaaaa tccatgttca tagctttttc tacatcacta attaccttta
    30661 cttcatgtcc atctcttttc aacacatttt caatcaactt taacatatct aactcatcat
    30721 ctactactaa tatcttagac ataataactc ctccatttat ccgtttaata gtattctaat
    30781 ttatatattt aataatatct ttaaaattca cattaaccat aatactctca tattatagct
    30841 tacaataatt aattactatt ttacaaataa aatattttag atacaaaaac tttatatttc
    30901 aaaaacttta tattcatttt acacgtattt acttaaatat aaaaatttat ttaacaattt
    30961 attattgtaa tattttgaat atataataaa attaataata agaaaacttt ttataaatat
    31021 acttttaatt gtttaaattg gaggaaaaaa ttatggatga aaagataaca aaaaataatt
    31081 ataatgttcc atttgactat gttcgaaaaa aactcaaaga attagaccct catacaatta
    31141 gtaatttaag taatatacct ttcaataatg atttaaatag attcacactc aatttttttg
    31201 atagacaata tattatagac tatccaagtg gagaagtttg gaatagtaat ggtagccttt
    31261 gcaataactt tgagcttaaa atcttgatag ttagatattt aatcaatgct aaaggtattc
    31321 ctagaactaa taaatatgta acttttaaag aaataccagg aggcaatgtt tattatccaa
    31381 attttttaaa ca
//
LOCUS       DAEPKC010000040        31038 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.040, whole genome shotgun sequence.
ACCESSION   DAEPKC010000040 DAEPKC010000000
VERSION     DAEPKC010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 31038)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31038)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31038
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.040"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(<1..92)
                     /locus_tag="KR294_001880"
     CDS             complement(<1..92)
                     /locus_tag="KR294_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HBH0239960.1"
                     /translation="MKKSVLLLDVDYTVINTDSMIDFFIYSLKN"
     gene            complement(126..1013)
                     /locus_tag="KR294_001881"
     CDS             complement(126..1013)
                     /locus_tag="KR294_001881"
                     /EC_number="2.4.2.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decaprenyl-phosphate phosphoribosyltransferase"
                     /protein_id="HBH0239961.1"
                     /translation="MKQTNTSIRLLTKISDYIKLMRIKQYIKNFFVFSAIIFSNNILN
                     INLFLNTFIAFVCFCLMSSSVYALNDAIDMDKDKKHPKKCNRPVASGRISKKSANILF
                     VVLALISVCLSTVVSFNLSIILSLYLINNILYSLKLKNIILLDVFSISLGFILRVYAG
                     CVAISVSLSNWIILCTFFLSLYLALGKRKKEIETLRDDAVEHRKILEDYDIENLNQMM
                     IVILSSTIVCYALYSTSNPEKPHMIFTTIFVVYGVLRYNYIINTTNENNPTDIVLKDN
                     ALKINVILWIITCLIILIF"
     gene            complement(1042..2280)
                     /locus_tag="KR294_001882"
     CDS             complement(1042..2280)
                     /locus_tag="KR294_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239962.1"
                     /translation="MDGDILMSKILKYKNEMFLFILVVITYLIITKIFFSKTTIFYDL
                     NNTYDVLLDTDTGVLFNLNVFAISQDNSKHILFSAIISIFAYPIYLFCTSIANPGTTD
                     FNSAYGFGLICLQIITSAMSITLVFNHIKKIKMQRLTLILLTMIMIFSFPQLFMTLNV
                     ERFIYSQFSLIFFIVIANKMKGKNSYLVELAAIPLFGITISNIYLYFFNMIFEFKLKI
                     GKMLKHLITFILMAYICVVSTKSYESFMNLGNVIQYDTKFISGEPILEKIAMIIERLL
                     YSVFYFPGASIKKGLFLQNGEVATIPVILTLLALCFCVLSVIENSEKRVPKLCMGIII
                     FNLTLHGIVGYNLVNSSIMAINFSFAVIILLAYFTKALRKNEKNMYNIFLSLLLVTIV
                     ISNVNGFIEILNIGIKSYPV"
     gene            complement(2664..3806)
                     /locus_tag="KR294_001883"
     CDS             complement(2664..3806)
                     /locus_tag="KR294_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBH0239963.1"
                     /translation="MRYVEYGKTGKMVSVVGYGGLRFDLEKSNQENADLVKYAYEKGI
                     NYFDTAPGYCDDRSEDIFGLAFRQMIKEGKTDFYVSTKEKPKACDTSEKAIEAVKKSI
                     ERLGVSKINFYHVWNIRKMEHYELAMRPGGQYEGLLKCKEEGLIDHIVFSSHQPGDEV
                     IDILSENKFEGVTMGINILNFPYRLKGAKYAVDNGYGVVAMNPLSGGTIPKYNKELSF
                     LSKDGESTIESALRFNIGISQISISLIGFNKKQDIDDACKIADENRIYSDEDIHDIET
                     RLNKNMNEICTGCGYCKVCPKGINTPAYMLFYNEKQMFKKSDEEMTKLVYGLGHWNYT
                     MNSKAKAKECISCGKCEVECTQHLPIIDRLKEIKKWEEDGANSVKV"
     gene            complement(3947..4813)
                     /locus_tag="KR294_001884"
     CDS             complement(3947..4813)
                     /locus_tag="KR294_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBH0239964.1"
                     /translation="MDNYKKVKQVLWIILFANFAVALLKIIIGNQIKSYSMTADGFHS
                     LSDGASNIVGLIGIFFASKPKDKNHPYGHKKFEIITSLFISGMLFVIAIKIILSAVLR
                     IANPVVPAITIESLIALIITLFINIFVCMYEYRIGTKLNSYVLISDSLHTRSDIFVSL
                     GVLVTLVGVKLGFPVIIESIVPIIISAFIIYSAYGIFRPSIGILVDRVAVDEDYIKEI
                     VFEFNEVRDVHNIRSRGSKSSIYIDMHVMVDPFISVEQSHDLTHKIEKQIQEEINENA
                     QVIVHIEPFYSF"
     gene            complement(5147..6694)
                     /locus_tag="KR294_001885"
     CDS             complement(5147..6694)
                     /locus_tag="KR294_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBH0239965.1"
                     /translation="MANFFNFILLQKDKIIELLIQHMSLTVTSILIAIIVGVPLGIII
                     SRISSLRKFVLGFVNLVQAVPSMALLGLLVPILGIGSKPAIFMVVVYSLLPIVKNTYI
                     GITSIDPVVLESAKGIGLTRNQTLFKIQFPLALPIIMGGVRISAVTAVGLMTLAAFIG
                     AGGLGYLVFSGVQTVNNNMILAGAIPSCIIALLVDYLFSKIEVAVTPKGLNPKAPKKN
                     YIALKVISVVLVVSMLFVVFSSSFSSKKDTITIGSKDYTEQLILGNVYAELVEKNTNL
                     KVKKNLNLGGSSVAFNAIKSGELDMYVDYTGTLLVNVMKHAPIKDADEAYNVVKDTME
                     KENQLTLLDPLGFNNTYTLAMMPETAEKYGINTISDLTKYGKEFTFSPTLEFENREDG
                     LVGLSRDYGLKFKDVKAMNGSLRYTALDNNESQVIDAFLTDGLIKKFNLKILEDDKNF
                     FVPYYAAPLVREDTLKKYPELEKVMNMLSGKINEETMRELNYQVDELGKSPEEVAHSF
                     LVKEGLV"
     gene            complement(6687..7823)
                     /locus_tag="KR294_001886"
     CDS             complement(6687..7823)
                     /locus_tag="KR294_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0239966.1"
                     /translation="MIEIRNVTKKIGNNVILDDISLVVETGTLVVLIGSSGCGKTTTL
                     KLINKLIKPTSGEIYINGKPISQENEIELRRKIGYVIQNTGLFPHLTIKENIELIPRL
                     KKEKSVEEIEKRTLQLLEMVGLDSDEFLNKYPSELSGGQQQRIGVARAIATDAEIILM
                     DEPFSALDPITRTSLQEQLFSLQDELKKTIIFVTHDMDEALKIADKICIMKDGRIAQY
                     DTPENILRKPANDFVKDFIGEDRVWDNPEYIKARDIMIKNPIAVNSTRTVTQGIEIMR
                     TSKVDSLLIIDRAKTLKGIVTVKDMKDIDDKSILLADIMSSEPLHVNEGDNLVEILNV
                     MNRNSVGYIPVISDENKLVGLITRSSLLSVLSEQFLEMEVSVLG"
     gene            complement(8086..9183)
                     /gene="dinB"
                     /locus_tag="KR294_001887"
     CDS             complement(8086..9183)
                     /gene="dinB"
                     /locus_tag="KR294_001887"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HBH0239967.1"
                     /translation="MKHYRKIIHIDMDAFYASIEQRDNKKLKGRPVIVGGNPQSRGVV
                     ATCSYEARKFGIHSAMPSAVAYNRCPYAVFVRPRFDVYKSVSEQIRDIFYRYTDLVEP
                     LSLDEAYLDVTKNKKNIDSSIEIAKQIKKDIFREVGLTSSAGVSYNKFLAKIASDLRK
                     PNGLTVITEENAQDFLDKLPVNKFFGVGKVTSNTLKNLGIKTGYDLRCLNLFELENIF
                     KKRGYELYKFARGIDDRPVEPNRVRKSVGAETTLSHNLDIDEEETRNILDELCEEVCH
                     RLKNSEKFGKTLTLKIKYEDFTKITRSLSLEHYIDEYNDIRSGVDNLLRNVDVNGKQI
                     RLLGVTISNLSDKKETYKDITLFEYMDSIQM"
     gene            complement(9573..11078)
                     /locus_tag="KR294_001888"
     CDS             complement(9573..11078)
                     /locus_tag="KR294_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003374392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HBH0239968.1"
                     /translation="MKVGFDHKKYLEEQSKYILERVNNFDKLYLEFGGKLMGDLHAKR
                     VLPGFDENAKIKVLQHMKEKVEVVICVYAGDIERNKIRGDFGITYDMEVLRLIDDLRG
                     YELDVNSVVITRFEGQPATTVFINKLERRGIKVYKHYPTKGYPSDVETIVSDEGYGAN
                     EYIETTKPIVVVTAPGPNSGKLGTCLSQLYHENKRGNVVGYSKFETFPVWNVPVKHPL
                     NIAYEAATVDLKDVNMIDSFHLETYGEMSVNYNRDLELFPVLKKIIEKITGKESIFQS
                     PTDMGVNRVGFGIIDDEVIRKASIEEIIRRYFKTACEYKKGQVDKGAYDRMKMIMEEL
                     NLKPEDRNVVLPARNYSNKLKESADKNDTCPVVALELEDGTILTGKGSDLMNGTAAVV
                     LNAIKHLANISDDMHLISPVILEPIINLKTKTLASRNVSLSCQEVLTALSICAVTNPT
                     AQFAMEKLALLKGCQAHSTTILNRDDEQTFRKLGIDVTCDPEYPSQNLYYS"
     gene            complement(11340..11690)
                     /locus_tag="KR294_001889"
     CDS             complement(11340..11690)
                     /locus_tag="KR294_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239969.1"
                     /translation="MAIVDKIFNEIKLMVARLLLGKKYSEYEEKDLVYNTEEEVILIT
                     LKRLVFQGNVNEAEEILFDKAKSVNSENMQYIAIEFYTMLMEKTDEELEAMNFSKQEV
                     YQGIEDIRKVLNLE"
     gene            complement(11913..12104)
                     /locus_tag="KR294_001890"
     CDS             complement(11913..12104)
                     /locus_tag="KR294_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239970.1"
                     /translation="MLDRFFGEGGFGGCAWWIIILFFLFLAFQDCWAEMDLCAWIPFL
                     ILLLILCECGDVFDGGCGC"
     gene            complement(12222..13148)
                     /locus_tag="KR294_001891"
     CDS             complement(12222..13148)
                     /locus_tag="KR294_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBH0239971.1"
                     /translation="MRKIVLKDILFLVTTLSIIVILLLVTNITTNSKIKSTSESYLKS
                     DKNSVRQNGIQRSTKSSTKNTAFKTTILNTGKSDCILVEIGNKVIMIDTGEDKNGKQI
                     VDRLKEKGINTLDYLILTHLDKDHIGGVDSVLSSVKVKNIIQANYKKDSKQYDEYIDS
                     LKKADIEPVLLKDNMNIVINSAEINIHPASKSKYESSNDYSIITNISYGAHKFLFAGD
                     AEEERLSEFINGNTLKYDFVKMPHHGRYDKLTETFLESISPQYAVITCSEKKEPEEGV
                     LKILERLNIKTFLTSNGEVVINSDGKTLSVNQ"
     gene            complement(13282..14778)
                     /locus_tag="KR294_001892"
     CDS             complement(13282..14778)
                     /locus_tag="KR294_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HBH0239972.1"
                     /translation="MFEFETQLKRLKHEVLTAVARLSIEENLTKENIEKIPYEIIKGE
                     KARYRCCVYKEREVVLERAQLALSLTPNSKYGDINPDSVSLDTDEQIIYIVEAACDRC
                     PINEFTVTELCRGCLAHRCKEACKFGAISYINGRAYINHDLCKACGMCKSSCQYDAIS
                     EVVRPCKSVCPTGALDFNRNTMKAMIHEDNCINCGACMSACPFGAISDKSLIAPVAKK
                     LAKKENMYAIVAPAITGQIDSNITYGQLKNAIKSLGFVDMIEASCGADAVTVHESNEL
                     IERIKSGDNYMTNSCCPGFFKYIEKMFPDEKDRISSTVSPMVATGRLVKKIDSDAKVV
                     FIGPCTAKKSEATEKSLKDSVDYVLTFEELMALFEAFNIDLSKCSNEDINDGSIFGRG
                     FGASGGLAKSVQNYIAEKGLSFDFEPIKVSGPRQIKKTMTMAKLGRLEGNFIEGMMCE
                     EGCINGAGKFLSGVKAKNTFDRKNGQSTKKSVLSNDKIKEFEDVNLER"
     gene            complement(15058..16548)
                     /locus_tag="KR294_001893"
     CDS             complement(15058..16548)
                     /locus_tag="KR294_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HBH0239973.1"
                     /translation="MFQFETQIHKLRHDVLTAIARLGKEDNLTREAMDNIQYEIIKGE
                     KPTYRCCVYKERAIISERVNVSMGLQPGQDKIDLDTMDIEEDEQIIYILEAACDSCPI
                     NEFTVTDICRGCLAHRCKEACKFGAITHVGGMAYINHELCKACGMCKKACQYDAISEV
                     VRPCKSVCPTNALGFDRENMKAMIHEDKCLNCGACMSACPFGAISDKSLIAPVARKLV
                     QKEKMYAVVAPAITGQVEANVTYGQIKNAIKSLGFVDVLEAACGADAVTVHESLEFAE
                     RMEKGEAFMTNSCCPGFVGYIEKTYPNHVGKISSTVSPMIASGRFIKSHEPDAKVVFI
                     GPCTAKKSEAAKKELKGAVDYVLTFEEIMALFEAFDIDLAKCSNEDIDDASIFGRGFG
                     AAGGLTKAIENYLAEKGIGVNFEPVKISGSREIKKTMTMANLGKLEGNFIEGMMCEGG
                     CINGSGKFLSGAKVKATFDRKNSQSTKKSVLANTKIKDFSNINLEK"
     gene            17015..17215
                     /locus_tag="KR294_001894"
     CDS             17015..17215
                     /locus_tag="KR294_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000809131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBH0239974.1"
                     /translation="MKNGIVKWFNNEKGFGFISVEGEDDVFVHFSAIQNDGYKTLEEG
                     EKVSFDITQGNRGPQAENVNRI"
     gene            complement(17395..18273)
                     /gene="speB"
                     /locus_tag="KR294_001895"
     CDS             complement(17395..18273)
                     /gene="speB"
                     /locus_tag="KR294_001895"
                     /EC_number="3.5.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatinase"
                     /protein_id="HBH0239975.1"
                     /translation="MKNNFYHMNTFMSMDKNYEESNLIVFGVGFDGTTSNRPGARFAS
                     SSMRKEFYGLETYSPFLDLDLEDYNICDYGDLEISVGSTEQVLKEIYQETYKIVRDSK
                     VPFMIGGEHLVTLPAFKAVHEKYNDIYVIHFDAHTDLREEYNNSKNSHATVIKRIWDI
                     VGDNKIFQFGIRSGTKEEFKFATEEKHTYMEIGGIDTFENIVNMLNGKNIYLTIDLDV
                     LDASVFPGTGTPEPGGVNYREFQEIFKIIKNSNINIVGCDIVELSPDYDTTGVSTVIA
                     CKILRELCLIISDKIK"
     gene            complement(18263..19114)
                     /gene="speE"
                     /locus_tag="KR294_001896"
     CDS             complement(18263..19114)
                     /gene="speE"
                     /locus_tag="KR294_001896"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HBH0239976.1"
                     /translation="MELWYTEEWTENVRFSIKVNKHLFEGKSQFQRIDVFDSDEFGKF
                     LTIDGLMMVTYKDEFIYHEMITHVPMATNLNIKKVLVIGGGDGGTVRELSRYPQIEKI
                     DMVEIDKMVVDVSKEYMDICSCKLDDKRVSLYFEDGVNFVKCAHDKSYDLIIVDSTDP
                     IGPGEGLFSTDFYKDCYRILTDDGILVNQSESPYFDFNAKEMKRANKKLKQIFPISEV
                     YQAHIPTYPSGHWLFGFASKKLNPVKNQDRNGWEKLSLKTKYYNSDIHLGSFMLPQYV
                     KEMLDEE"
     gene            complement(19144..19557)
                     /gene="speD"
                     /locus_tag="KR294_001897"
     CDS             complement(19144..19557)
                     /gene="speD"
                     /locus_tag="KR294_001897"
                     /EC_number="4.1.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylmethionine decarboxylase"
                     /protein_id="HBH0239977.1"
                     /translation="MKFETLGRHILVEYYNCDENVLKDPRLIENFMNDSALNAKATIV
                     DSVFHHFNPWGVSGAVIIAESHLTIHTWPEYGYAAADFFTCGDIDPWKSFELLEQLLK
                     SERSESTEIPRGLTTKIKKYSKKDLGKITHKPEAV"
     gene            complement(19644..21119)
                     /locus_tag="KR294_001898"
     CDS             complement(19644..21119)
                     /locus_tag="KR294_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HBH0239978.1"
                     /translation="MDSEFANAVELSYECAPLLESLKEYSEKDIACFDVPGHVKNRGV
                     AILNKYLGESLMKMDINSSPTMDNVAAPNGIIKNAQDLLAQAYMADEAFFITNGTTQA
                     IHAMILSVIKPGEKVLLPRNIHKSVINALILCGGIPIFIQPEFDEKLGISLNITLEKV
                     RKEIEKDCNIKALFFLNPTYYGVCADLESIIELCHKNNVLVLVDEAHGAHFPFHLDLP
                     PSAISLGADMVAVSIHKTGGALTQSSALLLNRDNVSFEKVLQSINMLQSTSASYLLMA
                     SIDGARVNLVENGEKQLSKALNLSRYAKSKLNKIDGIKVLSTEILKQKGVKFIDETKL
                     CINVKELNLTGFEVYDLLYKNFSIQVELGDSYNILALVSIGTNKSDIDRLVKALSIIA
                     KIYRKESTLNEFNMVQINPIIKLNPREAFYAPKESVGINSCIDRICGESIMAYPPGIP
                     IIAPGELITEEIMEYIIFLKNSNAYLTDVQDKNLDRILVIK"
     gene            complement(21757..22410)
                     /locus_tag="KR294_001899"
     CDS             complement(21757..22410)
                     /locus_tag="KR294_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH0239979.1"
                     /translation="MKVDPLTTQVYDYISKKIQNGEYEANQRITESEICKSIGVSRTP
                     AREALTRLAGENLLEKIPNKGFVVKEFQEKEKLDTYSVIGVLDALAGSSALQNLTESD
                     LVKMEELTEMMAVSIKYKNYNSYLKLSNEFHDIYITKSDNQVLVNLLNSLRYNFMSKS
                     YTSDNEDELYKMLTYSNNQHIEVVKSMRENDLENVERILREHWKTIPIAEMKKEKLL"
     gene            complement(22655..24520)
                     /locus_tag="KR294_001900"
     CDS             complement(22655..24520)
                     /locus_tag="KR294_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 13 protein"
                     /protein_id="HBH0239980.1"
                     /translation="MQSVIEYNSWDKNFKAPFGALKFDEELTICVKVNEGYNIKSISL
                     EINREEEMRTITLNEELDNDKLGKCFCGKIEKFDGTGVYFYYFKVDVEMDGQIKTLFY
                     GKNRDNGYSCEYNYSDINKYQITVYKDFKVPTWYKEGILYHIFVDRFNNGNRSGKVDN
                     PKKNSFIYGNWEDTPMYIKDSQGDVIRWDFHGGNLRGIINKLGYLKKLGVSILYLSPI
                     FEASSNHKYDTGDYKKIDPMFGDEDTFKELIDKAKEKGISIVLDGVFSHTGADSKYFN
                     MYGNYNSLGAYQSKESPYYSWYMFEEFPQKYKSWWDVKTLPNINELEHSYMDYIIYDN
                     DSVINKWVNMGIKGWRLDVADELPTKFIRELKKELKKADDDSILIGEVWEDASNKISY
                     GQRRSYLLGEELDSVMGYPFRNNMFSFLKGEINSYELCNRYMQIKENYPKESFRSNLN
                     LIGTHDVTRAKTELNDDVDLVKLAVAIQMTFEGVPYIYYGDEAGLCGGVDPDNRRTYP
                     WKNEDEDMLNFYRDVIKIRNKNKLLSSGNTEFIYTNNDSVFSFIRVNENNDRMLILVN
                     RSENVESISLCIESSFIEEIPIKYSLKNANSTIQIENNELKVDLDSKSFRIFRVN"
     gene            complement(24525..26945)
                     /locus_tag="KR294_001901"
     CDS             complement(24525..26945)
                     /locus_tag="KR294_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan phosphorylase"
                     /protein_id="HBH0239981.1"
                     /translation="MVTISKKKFKQKFEVKMYSLYAQSIKEATDEQLLNVLCSLLKDE
                     IAKKWVATKLDKKKEVYYFSLEFLIGRQLKSNLLNLNIEEEVREGLSELGINLDDLIE
                     TEVDPALGNGGLGRLAACFLDSMASLNISGQGYGIRYKYGLFEQKFVNGYQVEVPDNW
                     LTEGRYAWETVRPNEATMVKFGGEVELIKEGSHLKVIHKNYLPVMAMPYDIPIIGYQN
                     QCINTLRLFKSEIPKRDFGELTSNALNYSGSYEEALKHKYYTEEISQVLYPDDSNYAG
                     KLLRLKQEYFFVSAGIQDIIRKYKKNKLNINNLFDKVAIHINDTHPTLCIPELMRILL
                     DEENLSWDEAWEITKKTVSYTNHTIMSEAMEKWPVSMMKELLPRIYMIIEEINRRYVE
                     ELNNKGYDQDRIKRMSIIDCDNINMANLCIVTSHSVNGVAKLHTHILETEVLKDFYQD
                     EPNKFNNKTNGIAHRRWLISSNPQLSNLITDLIGDSWKKDTLQLKNIEKFKNDSSVLQ
                     RLDDIKYNNKANLAKFIKDKYDLNVDPSSIFDVQVKRLHAYKRQLLNIFNVLHMYHEL
                     LDNPNLNLDPRTFIFGAKAAPGYYLAKCIIKFINSVASTINNDVRVKDKLKVVFLENY
                     GVSLAEIIIPAANVSEQISTTTKEASGTSNMKFMMNGAITLATLDGANVEICEQVGKE
                     NMFLFGLSAEQVLNYNKYGGYSSLDLYHSNMDIKRVVDDLINGFIPNLGEEGRSIYNS
                     LTTYNDEYFVLRDFENYGQAQADINRLYRDKEKWNKMSLVNIANSGFFSSDRTISEYA
                     KDIWFKRV"
     gene            complement(26959..28401)
                     /gene="glgA"
                     /locus_tag="KR294_001902"
     CDS             complement(26959..28401)
                     /gene="glgA"
                     /locus_tag="KR294_001902"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011053260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HBH0239982.1"
                     /translation="MKVFYVTAECWPFAKTGGLGDVSYALPKELKKEGVDVRVIMPKY
                     STIPSYLKDQLKEIAVFSVRVGWRNQYCGLLEMELDGVKFYFIDNEFYFRREDERKSI
                     YGYGDDAERYTFFTDAVLEAISRIDFYPDVIHINDWHTGMLPLILKERYATLEGYKNI
                     KTMYTIHNLQYQGVFDKHVLYDILDLPQKYFDNGDIEYYGSINFMKAGINFADKIITV
                     SPTYANEIQTSFYGEQLDGLLRKESGKLKGILNGIDYDLNDPAKDKDIFVHYDVDSID
                     KKVENKLRLQDILGLKKDSSIPLIGIVSRLVSQKGFDLIAYMMPELMREDLQIVVLGT
                     GEHQYQSMFNYYDSNFSDKVSARITFNASLAQQIYAASDMFLMPSLFEPCGIGQMLAM
                     RYGSLPIVRETGGLRDTVTPYNKFTGEGNGFSFKNYNAHEMFFCLKNAIKVFKDKEKW
                     IKLVENAMKTDNSWKKSAKEYIETYRDICD"
     gene            complement(28430..29560)
                     /gene="glgD"
                     /locus_tag="KR294_001903"
     CDS             complement(28430..29560)
                     /gene="glgD"
                     /locus_tag="KR294_001903"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HBH0239983.1"
                     /translation="MRNECLGIINLNKKGDPAINKLNYGRPIASTPIAGRYRIIDFAL
                     SNMINSGITKVGIFAKEKYRSLTDHIGSGKDWDLSRKKGGLSIFSPENTKYRNTYSHR
                     EGDIYTILANLDYIEKSEEEYILIAPSYMLCNLNYSQALEYHKKSHNDITIIYKNVNN
                     ANKDFAGNLTLNLDSNNRVINVGNNLGKFPRANICMETYIMKREDFVECIYNIVNKGN
                     YCYLEEFIIEEAENMKIGAYEYTGYLKCVNSVESYFEMSKDLLNLEVADELLYSERKI
                     FTKEKNESPTIYTDSAKVENSFIASGCLIEGTVKDSIIFRKVNVEKGTVIENSIVMQN
                     CVIKSNAKLYNAILDKNTSVSNGKELRGDEKYPLVVEKNTNI"
     gene            complement(29562..30722)
                     /locus_tag="KR294_001904"
     CDS             complement(29562..30722)
                     /locus_tag="KR294_001904"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HBH0239984.1"
                     /translation="MKKEMLAMILAGGQGSRLGVFTKRIAKPAVSFGGKYRIIDFVLS
                     NCSNSGIDTVGVLTQYRPLILNSHIGMGSHWDLDRINGGVYVLQPFMNEKEGNWYNGT
                     AHAIYQNMDFVDTYNPEYVLILSGDHIYKMDYSKMLKFHKEKGSKATIAVIEVPWDEA
                     SRFGIMNTNEDSSIYEFEEKPSEPKSNLASMGVYIFDWKMLRNYFKEAEKNPEINYDD
                     FGKNLIPKMLEDNVGMYAYPFKGYWRDVGTIQSLWDANMDIIKSPETLDLADPKWKIY
                     TNTMAMPPQYIGKNANVHRSMIADGCRILGEVGNSVLSHGVVVGKGSKVIDSVIMPNV
                     VIGENVTIEKAMIGECATINDNVQIKNVNNEINVVSEYENIEPRCVLIEGGL"
BASE COUNT        10107 a         5464 c         3161 g        12306 t
ORIGIN      
        1 ttatttttta aagagtaaat aaaaaaatct atcatgctat cagtatttat aacagtataa
       61 tctacatcaa gtaataatac actttttttc ataagtattt ccccatccta tcactaaaaa
      121 tatcactaaa aaatcaatat tattaaacat gtaattatcc ataagattac gtttattttt
      181 aaagcattat cttttaagac aatatcagta ggattatttt catttgtagt gttaattata
      241 taattatatc taagtacacc ataaactaca aatattgttg taaatatcat atgtggcttt
      301 tctggattac ttgtagaata caatgcataa catacaattg tagaacttaa tataactatc
      361 atcatttgat ttagattttc tatgtcataa tcttccaata tttttctatg ttcaactgca
      421 tcatctctta gagtttctat ttctttttta cgttttccaa gagctaagta cagagataag
      481 aaaaatgtac ataaaattat ccaatttgat aaactaacac ttatggctac acatcctgca
      541 taaaccctaa gtataaaacc aagagatatt gaaaacacat ctaatagtat tatattcttt
      601 agtttaagag aatataatat attgtttatc aaatagagac tgagaattat agaaagatta
      661 aaactaacaa ctgttgataa acagactgaa attaaagcta atactacaaa tagtatatta
      721 gcactttttt tgcttattct tccacttgcc actggtctat tacatttttt aggatgtttt
      781 ttatctttat ccatgtctat agcatcattc agtgcatata ctgatgatga cattagacaa
      841 aaacacacaa acgcaataaa cgtatttaaa aataaattta tatttagtat gttgtttgaa
      901 aaaattatag ctgaaaatac aaagaaattc tttatatatt gctttattct cattaacttt
      961 atataatctg aaattttagt aagaagcctt atacttgtat tggtctgttt cataaactta
     1021 ctaccctttc aatattattt tttaaacagg atatgatttt atccctatgt ttaaaatttc
     1081 tataaatcca ttgacattac tgattactat agtaaccaat aacagcgata gaaatatatt
     1141 atacatattc ttttcatttt ttctaagcgc tttcgtaaag taagccaata aaattataac
     1201 tgcaaaacta aaatttatag ccataatact tgaattgact agattatatc ctactatacc
     1261 atgtaaagtt agattgaata taattattcc catacatagc ttaggaactc ttttttctga
     1321 attttcaata actgataaaa cacaaaaaca taaagctaat aatgtaagaa ttactggtat
     1381 tgtagcaact tctccatttt gcaaaaataa ccctttttta atacttgctc caggaaaata
     1441 aaaaaccgaa tacaataatc tctctataat cattgcaatc ttttccaaaa ttggttctcc
     1501 acttataaat ttcgtatcat actgtattac atttccaagg ttcataaaac tctcataaga
     1561 ctttgttgaa actacacaaa tatatgccat taggataaat gtaattaaat gttttaacat
     1621 ttttcctatt tttaatttaa actcaaatat catattaaaa aaatacaaat atatattact
     1681 aatagttatt ccaaatagag gaatagctgc taattctact aaataagaat tttttccttt
     1741 catcttattt gcaataacta tgaaaaatat taatgaaaat tggctatata taaatctctc
     1801 tacatttaaa gtcataaata actgtggaaa agaaaatatc attatcatag taagtaaaat
     1861 taaagttaat ctctgcattt ttatcttttt aatatgatta aagactaaag ttattgacat
     1921 agcactagtt attatttgta gacaaattag tccaaaccca taggcactat taaaatctgt
     1981 tgtcccagga tttgctattg aagtacaaaa taggtatatt ggatatgcaa aaattgatat
     2041 aattgctgaa aacaatatgt gcttactatt gtcttgactt atagcaaata catttaaatt
     2101 gaataaaact cctgtatctg tatctaacaa tacatcataa gtattgttta aatcataaaa
     2161 tatagtagtc ttagaaaaaa atatcttagt tattattaag taagttatta caactaatat
     2221 aaacaaaaac atctcgtttt tatattttaa tattttactc atcaatatat caccatccat
     2281 tcattatata ggatttgctg acacctacaa tttattcctt atatttaata gccatcttca
     2341 taatgttctt acttgtttta ttgtaattga ataactcttt atttacaacc acaatattta
     2401 ctttattgat gttataatca gtcaagtatt gtttatataa catagattag tgttgtataa
     2461 aatgagaatt tgtaagcaat attaatgtaa aatatttgaa aaactttata taaaaatata
     2521 caatgttgct tatggaatta aactataaca aattaaagca taatttaagg agacaaaatt
     2581 ataatctgtc tccttaaata ttaaaactat attttaaaac attactaaat actatacaaa
     2641 tttcaaatat agtataaaat taattagact ttaacactat tagctccatc ttcttcccat
     2701 tttttaattt cttttaatct atctattata ggtaaatgct gagtacattc aacttcacat
     2761 tttccacaag atatacattc tttagctttt gccttactat tcattgtgta attccaatgt
     2821 cctaagccat aaactaactt tgtcatttct tcatcactct ttttaaacat ctgcttttca
     2881 ttataaaaaa gcatataggc tggggtatta ataccttttg gacatacttt acaataacca
     2941 caacctgtac atatttcgtt catattctta tttaatctag tctcaatatc atgtatatcc
     3001 tcatctgaat aaattctatt ttcgtctgca attttacatg catcatctat atcttgtttt
     3061 ttattaaacc ctatcaaaga tatacttatt tgtgaaattc ctatgttgaa tcttaaagct
     3121 gattctatag tactttcgcc atcttttgat agaaaagaaa gttctttatt atactttgga
     3181 atagttccac cacttaatgg gttcattgcc acaacaccat atccattatc aacagcatat
     3241 ttggcacctt ttagcctata tggaaagttt aatatattta ttcccatagt tacaccttca
     3301 aacttatttt cacttagaat atctataacc tcatctcctg gttgatgaga tgaaaatact
     3361 atatggtcta tcaatccttc ttctttacat ttcaataatc cttcatattg acctccaggt
     3421 ctcattgcta gttcgtaatg ttccatcttt ctaatattcc aaacatgata aaaatttatt
     3481 ttagatacgc ctaatcgttc tattgatttt tttacagcct ctatagcttt ttctgatgta
     3541 tcacatgctt ttggcttttc tttagttgat acataaaaat cggtcttacc ttcctttatc
     3601 atttgtctaa aggctagtcc aaatatatct tcacttctgt catcacaata ccctggtgct
     3661 gtatcaaagt aattaatacc tttttcatac gcatatttga ctaaatcagc attttcttga
     3721 ttactttttt ctaaatcaaa ccttaatcct ccatagccaa ctactgaaac cattttccct
     3781 gtctttccat attcaacgta tctcattgta aattcctcct tagatatatt aagacttaat
     3841 ttctttatag aaaatattat accataaata atttttataa attatttatg gtataatatt
     3901 ttttttataa attatatttt tttataactt gtattttata actaagttaa aaactataaa
     3961 aaggttcaat atggactatt acttgagcat tttcattaat ttcttcttgt atttgtttct
     4021 caattttatg tgttaaatca tgagattgct ctacgcttat aaatgggtct accattacat
     4081 gcatgtcaat ataaatagaa cttttgctac ctctacttct gatattgtga acatccctta
     4141 cctcattaaa ttcaaacaca atttctttta tataatcctc atctacagcc actctatcga
     4201 ccaaaattcc aatagatggc ctaaatattc cataagccga ataaattatg aatgcagaaa
     4261 taataatagg aactatagat tctattatta ctggaaatcc taacttaaca ccaactaaag
     4321 taaccaatac acctagagac acaaatatat cacttcttgt atgcaatgaa tccgaaatca
     4381 aaacataact atttagttta gtcccaattc tatattcata catgcataca aaaatattta
     4441 taaaaagtgt aataattaaa gcaattaaac tttctatagt tatagcaggt acaactggat
     4501 tagctattct taacactgca ctaagaatta tcttaattgc tataacaaac aacataccac
     4561 ttataaataa actggttata atttcaaact ttttatgtcc ataaggatga tttttatctt
     4621 ttggtttaga tgcaaagaaa atacctataa gccccactat attagatgct ccatctgaca
     4681 aagaatgaaa tccgtctgct gtcatactat agctttttat ttgattacca ataatgattt
     4741 ttaataatgc tactgcaaaa ttagcaaata aaattatcca caatacttgc ttcactttct
     4801 tatagttatc cataacaaat tccccctccc ttcgattcaa taaagaaagc tatctatcaa
     4861 tatcaatcaa ccagacaata aaatcgtata taagcacatt tactatattt atattcaaaa
     4921 ttggttgtac ttgttcattc tatttgaaac ttaattataa ataaaaatcg taggtatggt
     4981 tttggtatac ataaaaataa gagactgtct caaaataaag ataatcttct tttttattgt
     5041 tgaaatgata aaatatattt gatttcatat aaaaaagagt gcctcatgaa ctaaaaagtt
     5101 cattttgaga cactccctta aatttttgat ataaactatt aattttttat actaagcctt
     5161 ctttaactaa gaatgaatga gcaacttctt ctggtgattt accaagttca tccacttgat
     5221 agttaagttc tctcatagtt tcttcattta tttttcctga aagcatattc ataacttttt
     5281 ctaactcagg atatttcttc aaagtatctt ctcttactaa tggtgctgca taatatggta
     5341 caaagaaatt tttatcgtcc tctaatatct taagattaaa ctttttaata agaccatcag
     5401 ttaaaaatgc atctataacc tgagattcat tattatctaa agctgtatat cttaaacttc
     5461 cattcattgc ttttacatct ttgaatttta aaccataatc tctagaaagc cctacaagac
     5521 catcttctct attttcaaac tccaaagttg gtgagaatgt aaattcttta ccatatttag
     5581 tcaaatcaga aatagtattt attccatact tttcagcagt ttcaggcatc atagctaatg
     5641 tgtaagtatt attaaatcca agagggtcaa gtaaagttaa ctgattttct ttttccatag
     5701 tatcttttac aacattatat gcttcatcag catctttaat cggagcatgt ttcattacat
     5761 ttaccaaaag tgtacctgta tagtcaacat acatgtctaa ctcaccagat ttaattgcat
     5821 taaacgcaac agatgaacca cctagattta aattcttctt aactttaaga ttcgtatttt
     5881 tttctactaa ttcagcataa acattgccaa gtataagttg ttctgtataa tctttagaac
     5941 caatagttat tgtatctttt ttacttgaaa aactagaact aaaaacaacg aacaacattg
     6001 aaacaacaag cactacagat attactttaa gtgctatata attcttctta ggtgcttttg
     6061 gatttaatcc ttttggagta actgcaactt caattttact aaataaataa tcaactaaca
     6121 gtgcaattat acatgatggg attgcccctg ctaaaatcat attattattt acagtttgaa
     6181 cccctgaaaa tactaaatat cccaaaccac cagcacctat aaatgctgca agagtcatca
     6241 aaccaacagc tgtaactgca gatattctaa ctccacccat tattatagga agcgctaaag
     6301 gaaattgtat tttaaataat gtctgatttc ttgtaagacc aataccttta gctgattcta
     6361 atactactgg gtcaatactt gttataccta tatacgtatt ttttacaatt ggtagtaatg
     6421 aataaaccac taccataaat atggctggtt tacttcctat accaagtata ggtacaagaa
     6481 gacccaaaag tgccatagac ggaactgctt ggactaagtt tacaaatcca agtacaaact
     6541 ttctaagaga tgagattctt gaaataatta ttccaagagg aacaccaact attatagcta
     6601 ttaaaataga tgtaacagtt agactcatat gttgtattaa aagctctata atcttatctt
     6661 tttgtaatag tataaagtta aaaaaattag ccaagaacac tcacctccat ttctaagaat
     6721 tgttcactta aaacagaaag taaactactt ctagtaataa gccctaccag tttattttca
     6781 tcagaaataa ccggaatata tccaaccgaa ttacgattca ttacatttag tatttctact
     6841 aaattatcac cttcatttac atgcaaaggc tcacttgaca taatatcagc aagtaatatt
     6901 gacttatcat caatatcttt catatctttt acagtaacaa taccttttaa tgtttttgct
     6961 ctatctataa ttagtaagct atcaacctta ctcgttctca taatttctat tccttgagtt
     7021 acagttctag tagaattaac agcaatagga ttttttatca taatatctct tgcttttata
     7081 tattctggat tatcccaaac tctatcttct ccgataaaat cttttacaaa gtcatttgca
     7141 ggctttctaa gtatattttc gggagtatca tattgtgcta ttcttccatc cttcataata
     7201 caaattttat cagctatctt taaagcctca tccatatcat gagttacaaa tattatagtt
     7261 tttttcaatt catcttgaag agaaaataat tgttcttgta aagatgttct cgttattggg
     7321 tctaaagcac taaaaggctc atccatcaat attatttcag catcagtagc aatggctctt
     7381 gcaacaccga ttctttgttg ctgtccacca ctaagttctg aaggatactt attcaaaaat
     7441 tcatcactat caagtcctac catctcaagt agttgcaacg ttcttttttc aatttcttca
     7501 acggattttt ccttttttag gcgtggaatt agctctatat tttcttttat tgtaagatga
     7561 gggaataggc ctgtgttctg tataacatat cctatttttc ttctaagctc tatttcattt
     7621 tcctgagaaa ttggtttgcc attaatatat atctcaccag atgtaggttt tattaatttg
     7681 tttataagct tcaaagtagt agtctttcca caaccacttg aaccaatcaa aactaccaat
     7741 gtacctgttt ctacaactag agaaatatca tctaatataa cattatttcc tatttttttt
     7801 gttacatttc ttatctctat cataatttat catccccttt ttcgaacaag caaccttctt
     7861 caatattata agttgttttt ataattatat catactattt tatttatgta aacaaagtac
     7921 gatttttagg tcactatttg tctgaatatt gctacaaata taaagtattt atatatagta
     7981 tataatacat aatgtcaaaa aacaaaaaat ataaaaatat tcataaaata acactagcct
     8041 caattatata gtattaaagc tagtgttatt tcatttaaac aaaactcaca tttggatact
     8101 atccatgtat tcaaataatg taatatcttt ataagtttct tttttatcac ttaggtttga
     8161 tattgtaact cccaatagcc taatttgttt tccattaaca tcaacatttc tcaacaaatt
     8221 atctacacca cttcttatat cattatattc gtcaatatag tgttctaaac taaggcttct
     8281 agttatcttt gtaaagtcct catatttaat ttttaatgtt aatgtttttc caaacttctc
     8341 agagtttttt aatctatgac atacttcttc acaaagttca tcaagaatgt tgcgtgtttc
     8401 ttcttcatca atatccaaat tatgacttaa tgtagtctca gccccaacag attttctaac
     8461 cctatttggt tccactggtc tatcgtctat tcctctagca aatttatata attcataacc
     8521 tctttttttg aatatatttt caagttcaaa taaatttaaa caccttaaat catatccagt
     8581 ttttatacct aaatttttaa gagtatttga agtaactttt ccaacaccaa aaaatttatt
     8641 cacaggtaat ttatctaaaa agtcctgggc attttcttcg gttattacag ttaacccatt
     8701 tggctttctt aagtctgatg caatcttagc aagaaactta ttgtatgaca caccagctga
     8761 agaagtaaga ccaacttctc taaatatatc tttttttatt tgctttgcta tctcaattga
     8821 tgaatcaata ttttttttat tttttgttac atctaagtaa gcttcatcta aagataatgg
     8881 ttcaactaaa tccgtgtatc tataaaatat atctcttatt tgctctgaca cactcttata
     8941 aacatcaaat cgaggtctta caaaaactgc atatggacac ctattgtaag ctacagctga
     9001 tggcatagct gaatggatac caaattttct agcttcataa gaacacgttg caaccacacc
     9061 tcggctttgt ggatttccac cgacaataac aggtcttcct tttaattttt tattatctct
     9121 ttgttctata gatgcataaa aagcgtccat atctatatga attatttttc tataatgttt
     9181 cattattatc accttttaaa gtataaatag attaatttta tttatattac tttttaatta
     9241 taccaaactt atgtttcttt ttggtatttt ttcattattt tctttatata ttcatatttt
     9301 ccataaataa aaccatctat aatccattaa cttcaatata atttataaaa aatccttaaa
     9361 aacacttgca aaaactatat aaaagcttta caataggtat tccaaggaac taaatttaaa
     9421 attccttatg gataacagta tatatattta atttatggga tgttttaaaa acaaaagact
     9481 gtcttatgca agacagccta ctgattttat tataattgta atggactgct caaactatta
     9541 ctttaaaaca gcccatattt ttttatataa ttttaactat agtaaagatt ttgtgaagga
     9601 tattctgggt cacaagttac atctatacca agctttctaa atgtttgttc atcatctcta
     9661 tttaatatag tagtagaatg agcttgacac ccttttaata atgctaactt ttccatagca
     9721 aattgtgcag ttggattagt tacagcacaa atactaagtg cagttaacac ctcttggcaa
     9781 ctaagtgaaa catttctact agctaaagtc tttgttttta agtttatgat aggttctaat
     9841 attacaggtg atattaagtg catatcatca gatatattgg ctaaatgttt aatggcattt
     9901 aatactactg ctgcagttcc attcattaaa tcagaaccct taccagttaa tattgtacca
     9961 tcttctaatt ctaatgcaac tacaggacaa gtatcattct tgtcagcact ttctttcaat
    10021 ttattactgt agtttctagc aggtaataca acatttctat cttctggctt taagttaagc
    10081 tcttccataa tcattttcat tctatcataa gcacctttat caacttgtcc ctttttatac
    10141 tcacaggcag ttttaaagta tcttcttatt atttcttcta tagaagcttt tcttattact
    10201 tcatcatcta ttattccaaa gccaactcta ttaacaccca tatcagttgg agattggaaa
    10261 attgattctt ttccagttat cttttctatt atttttttaa gcactggaaa taattccaaa
    10321 tctctattgt agtttactga catttcacca tacgtttcaa ggtggaatga atctatcata
    10381 ttcacatctt ttaaatcaac tgtagctgct tcataagcta tattcaaagg atgttttaca
    10441 ggtacattcc aaactgggaa tgtctcaaac ttagaatatc caactacatt acctctttta
    10501 ttttcatgat acaactgact tagacaagta ccaagttttc cactattagg tcctggtgct
    10561 gtgactacta ctattggctt tgtagtttct atatattcat ttgctccata tccctcatca
    10621 ctaactatag tctcaacatc tgacggatat ccctttgttg gataatgctt ataaacttta
    10681 attcctctac gttctaattt atttataaat acagttgtag caggttgtcc ttcaaatcta
    10741 gtaattacta cactatttac atctagttca taacctctta aatcatctat taatcttaaa
    10801 acttccatat cataagtgat accaaagtct cctcttattt tgtttctttc tatatctcct
    10861 gcatagacac aaattacaac ttcaactttt tctttcatat gttgtaatac ttttatcttt
    10921 gcattttcat caaatcctgg aagtactctt tttgcatgaa ggtctcccat caattttcct
    10981 ccaaactcta aataaagttt gtcaaaatta tttactcttt ctaagatata tttagactgc
    11041 tcttctaaat attttttgtg gtcaaatcct actttcatct taacacctca ctaaattaaa
    11101 tttcttattg ataacagtat atttatatat atttttttag taaaacatct tataaaaaaa
    11161 tgttaatact ttttcactca aagtaatatt atacaattaa gattaatttt tttcaagata
    11221 gttttatggt aaataagata tacctaatat aactaataaa ataagaatac tatattttta
    11281 tatataagta taatattctc accttagcat taatttattt caatattttc atatatcttt
    11341 tattctaaat tcaatacttt tctaatatct tctatacctt gataaacttc ttgtttagaa
    11401 aaattcatag cttctaattc ttcatcagtt ttttccataa gcatagtata aaattctatt
    11461 gctatatact gcatattttc actatttaca ctcttagctt tatcaaataa aatttcttct
    11521 gcttcgttta catttccctg aaaaactaat ctttttaaag ttataagtat aacttcttct
    11581 tctgtattat acactaaatc tttttcttca tattcactgt atttttttcc caataaaagt
    11641 cttgcaacca taagttttat ctcattgaaa atcttatcca ctatagccat ttttacatct
    11701 cctataaata aattttattt tctttttaat tatatcagac tttatcgtaa aaattattat
    11761 atgtaaatga aataattcaa aaataaattt taacaataaa aaaaagaagg tagcggggga
    11821 tttccgacta ccttcaaaca ctagattgtg attggtttgg tattttattt atacccacca
    11881 taagctttat taaatcatct aaattgattt ttttagcatc cacatcctcc atcaaaaacg
    11941 tcaccacatt cacaaagtat taataataat attaagaaag gtatccatgc acataagtcc
    12001 atttcagccc aacaatcttg gaatgctaag aataagaaga ataatattat tatccaccaa
    12061 gcacatccac caaatccgcc ttcaccaaaa aatctatcca acataatatg ttacctccta
    12121 gtcattttgt atgtggagtt tcagctccta aaatatacta tgtttaaggg gtaatatttg
    12181 ctaatgattt ttttaaattt ttttagatat ttttaaaaaa attattgatt cacactcaat
    12241 gtcttaccat cactattgat aactacctct ccattagaag tcaaaaatgt ttttatattc
    12301 aatctttcca atatttttaa aacaccttcc tctggttctt ttttctctga acatgtaata
    12361 acagcatatt ggggtgaaat agactctaaa aatgtttcag ttaatttgtc atatcttcca
    12421 tgatgaggca ttttaacaaa atcatatttt aaagtatttc catttataaa ctctgacaat
    12481 ctttcttcct ctgcatctcc tgcaaataaa aacttatgtg ctccatagct tatattagtg
    12541 attattgaat aatcatttga actctcgtac ttgctttttg aagccggatg tatgtttatt
    12601 tctgcactat tgattacaat attcatatta tcttttagta gcactggttc tatatcagct
    12661 tttttaagtg agtcaatata ttcatcatat tgcttactat ctttcttata atttgcttgt
    12721 ataatattct ttactttaac actagataac acactatcta ctccacctat atggtcctta
    12781 tctaaatgag ttaaaattaa atagtcaagt gtatttattc ctttttcttt taacctatcc
    12841 actatttgtt ttccattttt atcttctcct gtatcaatca ttatgacttt gttacctatc
    12901 tcaaccaata tgcaatcaga ctttccagtg tttagtatag tagtcttaaa tgcagtattt
    12961 tttgtgctac tctttgtgct cctctggata ccattttgcc tcacactatt tttgtcactt
    13021 tttaaataag attcacttgt tgattttatc ttactattag tagttatatt tgttacaagc
    13081 aataatatta ctattataga taatgtagta actaaaaaca ggatatcttt taatactatt
    13141 ttcctcatcc aaaagctcct ataaatttta tttattacat atttatagta tagcaacctt
    13201 aaatctgtaa aatacacata taaaaagggc aaattttagg catatttgtg gcatgataaa
    13261 aaaatgactg taccaaaaca attatctttc taaatttaca tcttcaaatt ctttaatctt
    13321 atcattagat aaaacactct ttttagtaga ttgtccattt tttctatcaa aagtattttt
    13381 agcttttaca cctgataaaa acttacctgc tccattaata caaccttctt cacacatcat
    13441 tccttctata aaattacctt ctaatcttcc caatttagcc attgtcattg tctttttaat
    13501 ttgtcttgga ccagatactt ttataggttc aaaatcaaaa ctaagcccct tttcagcaat
    13561 atagttctgt actgatttgg caagtccacc agatgctcca aatccccttc caaaaatcga
    13621 accatcattt atatcttcat ttgaacattt tgataaatct atattaaatg cttcaaataa
    13681 tgccattagt tcttcaaaag taagtacata atctactgaa tcttttaaac ttttctctgt
    13741 tgcctcactc tttttagctg tacatggccc tataaataca actttagcat cagaatctat
    13801 tttttttact aatcttcctg ttgctaccat aggagacact gtagatgata ttctatcttt
    13861 ttcatctggg aacatcttct ctatatactt aaaaaatccc ggacaacatg aatttgtcat
    13921 gtaattatct cctgatttta ttctttcaat aagttcattg ctttcatgaa ctgtaactgc
    13981 atctgctcca caggaagctt ctatcatatc tacaaatccc agtgatttta tagcattttt
    14041 taactgacca tatgtaatat tactatctat ttgacctgtt atagctggag ctactattgc
    14101 atacatattt tctttctttg caagtttttt tgcaacaggt gctatcaaac tcttatcaga
    14161 tattgctcca aaaggacatg ctgacataca tgctccacaa tttatacaat tatcttcatg
    14221 tatcattgct ttcatagtgt ttctattaaa atccaaagct cctgttggac aaacgctttt
    14281 acaaggtctt acaacttctg atatagcatc atattgacat gaacttttgc acattccaca
    14341 agccttacat aaatcatgat ttatatatgc tctcccattt atataagaaa ttgccccaaa
    14401 tttacatgct tccttacatc tatgagccaa acaccctcta caaagctctg taactgtaaa
    14461 ttcatttatt ggacatctat cacatgctgc ttcaactata tatataattt gctcatctgt
    14521 gtccaaacta actgaatctg gatttatatc tccatattta ctatttggag ttaaacttaa
    14581 tgcaagttgc gccctttcaa gaactacttc tctctcttta taaacacaac atctatatct
    14641 cgccttttct cctttaatta tttcatatgg aattttttct atattttctt ttgttaaatt
    14701 ttcttcaata gatagtcttg ctactgctgt taaaacttca tgttttaacc tttttagttg
    14761 cgtttcaaat tcaaacataa gtaatcctcc ctataaatca cacctttttg ctatatttct
    14821 actattatgt atattgtatt ttttatttat ttctataaat tattataaca taggcatata
    14881 ctttgttaag ttatatacaa aatattatat atgtaatttt tattttaagt gtatataatt
    14941 tttattttag ttgttcaata attaaatata taaataaaaa tagagttgtc caaaagttaa
    15001 acctcaactt agaacaactc tattaacaat atgtattttt gttgctttgt attatcttta
    15061 tttttctaaa tttatattac taaaatcttt tatctttgta tttgctaaga cacttttctt
    15121 agttgattga gaattttttc tatcaaaagt ggctttaacc tttgcacctg ataagaattt
    15181 accagaacca tttatacaac caccttcaca catcattcct tctataaaat taccttctag
    15241 ctttcctaaa ttagccatag tcatagtttt cttgatttct cttgaaccag aaatctttac
    15301 aggttcaaaa ttaacaccaa tacctttttc agcaagataa ttttctatag cttttgtaag
    15361 accaccagca gctccaaaac ctcttccaaa aattgatgca tcatctatat cttcatttga
    15421 acacttagcc aagtctatat caaatgcctc aaataatgcc attatttctt caaaagtaag
    15481 tacataatca acagctcctt ttaattcttt cttagctgcc tcactctttt tggctgtaca
    15541 tggtcctatg aatacaactt tagcatctgg ttcatgactt tttataaatc taccactagc
    15601 tatcatagga gacactgtag aagatatttt tcctacatga tttgggtatg ttttttctat
    15661 ataaccaaca aatcctggac aacaagaatt tgtcataaaa gcttctccct tttccattct
    15721 ttcagcaaat tctaagcttt catgaactgt aactgcatct gctccacaag ctgcttctaa
    15781 tacatcaaca aatcctagtg attttatagc attttttatt tgaccatatg taacatttgc
    15841 ttcaacttga cctgttatag ctggagctac caccgcatac attttctctt tttgaactaa
    15901 ctttctagct acaggagcta tcaaactctt atcagatatt gctccaaatg gacatgctga
    15961 catacatgct ccacagttta aacatttatc ctcatgtatc atagctttca tattttctct
    16021 atcaaatcct aaggcattag ttggacaaac actcttacat ggtctaacaa cctctgagat
    16081 ggcatcatat tgacaagctt ttttacacat tccacaagcc ttacataatt catgatttat
    16141 ataggccatt cctccgacat gtgttatagc tccaaattta caagcttctt tacatctatg
    16201 tgctagacat cctctacaaa tatctgttac tgtaaattca tttattggac aactgtcaca
    16261 tgcagcttcc aaaatatata taatttgttc atcttcttct atatccattg tatctaaatc
    16321 tatcttatct tgacctggtt gtaaccccat acttacattt actctctcag atattatagc
    16381 tctttcttta taaacacagc atctgtatgt aggtttctca ccttttatta tttcatactg
    16441 aatattatcc attgcttctc tggtaaggtt atcttctttt ccaagtctag ctattgcagt
    16501 taaaacatca tgtcttaatt tgtgtatttg tgtttcaaat tgaaacattt taataccacc
    16561 cccgtaaatg attttatacg ataccattat aacacaatat gtccttttat taatatatac
    16621 ataaaatatt atatgtttaa attttatttt atcgaatata tatagtgttt ttttgtttta
    16681 ttatataata ttattgatat ttctgaaatt tcactatttt tatttttact tttcaatcta
    16741 atatataata ttttttatta tatattttaa ttttgctttt tacttacata cctttttgtt
    16801 acattttttg atattaaatt tattatctac atttacattt tcgtcaaatt ttacaatact
    16861 tatcactgta taatttaaca atttttatta aattctaaaa gtaattaatt tttttaaaaa
    16921 ttttatttgc ttttatttaa aatttatgtt atattaatag aacagactta tttttttagt
    16981 ttgtattttt taataatgcg gaggttttct tataatgaaa aacggaatag taaaatggtt
    17041 taacaatgaa aaaggatttg ggttcatatc tgtagaggga gaagatgatg ttttcgtaca
    17101 tttctcagct atacaaaatg atggatacaa aactttagaa gaaggcgaaa aggttagctt
    17161 tgatataact caaggtaata gaggacctca agctgaaaac gtaaatagaa tataattatt
    17221 taatttaaat atatatattt tagaaaagga gctatcgagg gctctttttt gttgtttatt
    17281 atatttattt ttaattacaa aaataagaag ttactttaga aaagcgtcaa acttaaacta
    17341 acttttttaa aataacttct tatattataa tatatactat ttatataaaa tactctattt
    17401 aattttatca gatattatta agcataactc tcttaagatt ttacaagcta taactgtcga
    17461 tacacctgtt gtatcgtaat cagggcttaa ctctacaatg tcacaaccaa ctatatttat
    17521 attagagttt tttataatct taaaaatctc ttgaaactct ctataattta caccaccagg
    17581 ttctggtgta cctgttcctg gaaacacaga tgcatccaat acatctaaat ctatagttag
    17641 ataaatattc tttccattta gcatattaac tatattttca aacgtatcta ttcctcctat
    17701 ttccatgtat gtgtgttttt cttctgtagc aaatttaaat tcttcttttg tcccagacct
    17761 tataccaaat tgaaatattt tattatcacc tacaatatcc catattcttt taattactgt
    17821 tgcatgagaa tttttactat tattatattc ttccctcaaa tcagtatggg catcaaaatg
    17881 aattacatat atatcattgt acttttcatg tactgcttta aaggctggta atgtaactaa
    17941 atgctctcct ccaatcataa agggtacctt tgaatctcta acaatcttat atgtctcttg
    18001 atagatttct tttaagactt gttctgtact tccaacacta atttctaaat ctccataatc
    18061 acatatatta taatcctcta aatccaaatc taaaaaagga ctatatgtct caagaccgta
    18121 aaattctttt ctcatagagc tacttgcaaa tctagcccca ggtctgttag aagtagttcc
    18181 atcaaatcca acaccaaata ctataagatt agattcttca taatttttgt ccatactcat
    18241 aaaagtgttc atatgataga aattattctt catctagcat ctccttcacg tattgaggta
    18301 acataaacga acctaaatgt atatcactat tataatattt agtttttaaa cttaatttct
    18361 cccatccatt tctatcttga ttttttactg gattaagttt ttttgaagca aatccaaaca
    18421 accagtgacc agatggatat gttggtatat gtgcttgata aacttctgat attggaaata
    18481 tctgttttaa ttttttatta gctcttttca tctctttagc attaaagtca aaatacggac
    18541 tttcactttg atttactaaa attccatcat cagtcagtat tctataacaa tccttataaa
    18601 aatcagttga gaaaagccct tcgcctggtc ctattgggtc agttgaatct actattatca
    18661 ggtcatatga tttatcatgt gcacacttaa caaaattaac accatcttca aaatataaac
    18721 tcactctttt atcatctaat ttacatgagc atatatccat atactcctta gatacatcta
    18781 caaccatttt atctatttca accatgtcaa tcttttctat ttgaggataa cggcttaatt
    18841 ctcttactgt acctccatca cctccaccta tgactaatac tttctttatg tttaaatttg
    18901 tagccatagg aacatgagtt atcatctcat ggtatataaa ttcatcttta tatgttacca
    18961 tcattaatcc atctattgtt agaaattttc caaattcatc actatcaaat acatctatcc
    19021 tttgaaattg agactttcct tcaaatagat gtttatttac ttttatagaa aatcttacat
    19081 tttctgtcca ttcttctgta taccaaagtt ccatataata atcctcactt tctcttgtat
    19141 gttttatact gcttctggtt tatgagtaat cttacctaaa tctttttttg aatatttttt
    19201 aatttttgta gttaagcctc ttggaatttc tgtagactcg cttctttcag actttaaaag
    19261 ttgctctaat aattcaaaac ttttccatgg gtctatatca ccacaagtaa aaaaatctgc
    19321 tgctgcataa ccatattcag gccatgtatg tattgtcaaa tgagattcag caattataac
    19381 agctcctgaa accccccaag gattaaaatg gtggaataca gaatccacaa ttgtcgcttt
    19441 tgcatttaat gctgaatcat tcataaaatt ttctataaga cgtgggtctt taagtacgtt
    19501 ttcatcacaa ttatagtatt ctactagtat atgtcttcct agtgtttcaa atttcatttc
    19561 aaccccaact cctttatact tttaataagt tctatttgat aaactctact taacaaacac
    19621 ttgcccttgc aaaataaagt aatttatttt attactagta ttctatctaa gtttttatct
    19681 tgtacatctg taagatacgc attgctattt tttaagaaaa taatatactc cataatttct
    19741 tctgttatca attctcctgg agcaataatc ggtatacctg gtggatatgc cattattgat
    19801 tctccacaaa ttctatctat acatgaattg attcctacac tttcctttgg tgcataaaaa
    19861 gcttctcttg gattaagttt aataattgga tttatttgaa ccatattaaa ttcatttaat
    19921 gttgattctt ttctataaat ctttgcaatt atagaaagtg cctttactaa tctatctata
    19981 tctgatttat ttgttccaat ggacacaagt gccagtatat tatatgaatc tcccaattct
    20041 acttgaattg aaaaattttt atataataaa tcgtatactt caaatccagt caaatttaat
    20101 tcttttacat ttatacacaa ttttgtttca tctataaatt taacaccttt ttgtttcaat
    20161 atttctgtag ataaaacttt tattccatca attttgttta atttagattt tgcataccta
    20221 gatagattta atgcttttga cagttgcttt tcaccattct caactagatt aactctagca
    20281 ccatctatac ttgccataag caaataagat gctgatgttg attgtagcat attgattgat
    20341 tgaagaacct tttcaaaact tacattatct ctattcaata agagtgctga agattgtgtc
    20401 aatgctcctc cagttttatg tatacttaca gctaccatat cagctcccaa acttattgca
    20461 gaaggaggta aatctaaatg aaatggaaaa tgtgcaccat gagcttcatc aactaacact
    20521 aaaacattat ttttatggca tagttctata atactctcaa ggtctgcaca aactccatag
    20581 taagttggat taaggaaaaa taatgctttt atattacaat ctttttctat ctcttttcta
    20641 actttttcaa gagtaatatt taaacttata cctagttttt catcaaattc tggttgtata
    20701 aatattggta ttcccccaca aagtattaac gcatttatta ctgatttatg tatatttctt
    20761 ggaagtaata ctttttcacc tggttttata acactcaaaa tcattgcatg tattgcttga
    20821 gttgtgccat tcgttataaa gaatgcctca tcagccatat atgcttgtgc tagcaaatct
    20881 tgtgcatttt ttataatccc atttggggca gctacattat ccatagttgg tgatgaattt
    20941 atatccattt tcatgagact ttcacctaga tatttattta atatagctac acctctattt
    21001 tttacatgtc caggcacatc aaaacaagct atatctttct ctgagtattc ctttaacgac
    21061 tctaataatg gagcacactc atagcttaat tcaactgcat ttgcaaactc gctatccatg
    21121 atttcaaatt catctcctct ctatattcaa atatttttaa tatttattat ttattatttc
    21181 tattttttat ttttactttt attaaactca tgatatttat tatattaaca tcccagcatt
    21241 tttacaagtg tttttttgaa gttactcaaa aacatataca ttagctatat caatatttat
    21301 aaacttttta attttttgtt gtttatatta atttttttaa aacttagtat ttataaactt
    21361 tcttattttt tattattttg gtttttttac ttttttgagt tttagtaagc ttttgagttt
    21421 actattttta atttataagt attttattac taaactttta tattattctt atttcacata
    21481 tcaaaattct tggtttagtt ggactaaata attttcctat ttttgtattt taattttaat
    21541 ataaaattta ttaaattttt taattgataa aataaattct atatttatga tattaaaatt
    21601 ctataagttc attgatttat atatgttaat ttaaatacat tattctatcg tagtgcctta
    21661 gagtttttat ttgtatttaa agttaaattt attcttgttt ttcctttaat atttaatagt
    21721 aaaacaacaa aattataaaa aaaataaaga gaaactttat aaaagcttct cttttttcat
    21781 ctctgctata ggtatcgttt tccaatgttc tctcaaaatt ctttcaacat tttctaaatc
    21841 attctccctc atagatttta ctacttcaat atgttgatta ttgctgtatg tcaacatttt
    21901 atataactca tcttcattat cactagtata tgactttgac ataaaattat atcttaaaga
    21961 gttcaataga tttactaaca cctgattatc tgatttagtt atgtatatat cgtgaaattc
    22021 attacttaat tttaaatagc tattgtaatt tttatacttt atagagaccg ccatcatttc
    22081 tgttaattct tccattttta ctaggtctga ttcagttaaa ttttgtaatg ctgaagaacc
    22141 ggctaacgca tccaatactc caattacgga ataggtgtct aatttctcct tttcctgaaa
    22201 ttcttttact acaaatccct tattaggtat tttttctagt aaattttcac ctgctaacct
    22261 agttaatgct tctctcgctg gtgttctact aactccgata gatttacaaa tctcagattc
    22321 agtaattctc tgattagctt catattctcc attttggatt ttctttgata tatagtcata
    22381 tacttgagtt gtaagtggat ctaccttcat aagacgttcc tccatattaa gattataaaa
    22441 gttaaatctc cctacaactt tggtagagag ttcagtttta tcttactaat ttatataata
    22501 tcacaattat gatatttttt atacttcttt gtaatatttt gaaatactaa aattcttatg
    22561 ataatttata caaaaaaagt agaaaaagtt ttgataaaac aaaactcttt ccacattcgc
    22621 cttattttct atttattttt ctaaaaaaag atatttaatt tactctaaaa attctaaatg
    22681 atttagagtc taaatctact ttcaactcat tattttcaat ttgtatagta ctatttgcat
    22741 ttttaagact atactttata ggtatttcct caataaaact actctctata cataatgata
    22801 tactttccac attttcactt ctatttacta aaattaacat tctatcatta ttttcattaa
    22861 ctctaataaa agaaaataca gaatcattat tagtatatat aaattctgta tttccagaac
    22921 ttaaaagttt attcttattt ctaattttta taacatctct ataaaaatta agcatatctt
    22981 cgtcttcatt tttccatgga taagttcttc tattatctgg atcaacacct ccacaaagac
    23041 ctgcttcatc tccataatat atatatggta ctccttcaaa tgtcatctgt atagctacag
    23101 caagcttcac taaatctaca tcatcattta attccgtttt agctcttgta acatcatgtg
    23161 ttccaattaa atttaaatta gacctaaatg attcttttgg ataattttct ttaatctgca
    23221 tatatctatt acaaagttca tatgaattaa tttctccttt taagaaagaa aacatgttat
    23281 ttctaaaagg ataacccata acagaatcta attcttcacc taataaataa cttcttctct
    23341 gaccatagct aatcttattt gatgcatctt cccatacttc acctataaga attgagtcat
    23401 catctgcctt ttttaattcc ttttttaact ctcttataaa cttagttggt aattcgtctg
    23461 caacatctag tctccagccc ttaataccca tatttaccca tttatttata acgctatcat
    23521 tgtcatatat tatataatcc atatagctat gttctaattc atttatattt ggcaatgtct
    23581 taacatccca ccaactttta tatttttgag gaaattcttc aaacatatac catgaataat
    23641 atggagattc tttagattga tatgctccta aactattata gtttccatac atattaaaat
    23701 atttactatc tgctccagta tgactaaaaa ctccatctaa tactattgat ataccttttt
    23761 cttttgcttt atcaataagt tctttaaatg tatcttcatc tccaaacatt gggtcaattt
    23821 ttttatagtc acctgtatca tacttatgat tactagaggc ttcaaatata gggcttagat
    23881 atagtatact tacacctaat ttttttaaat atccaagttt attgattatc cctcttaaat
    23941 ttccaccatg gaaatcccat cttataacat ccccttgact atcctttatg tacataggtg
    24001 tatcttccca atttccatat atgaaactat tttttttagg attatcaacc ttaccactac
    24061 gatttccatt attgaatcta tctacaaata tatgataaag tattccttct ttgtaccatg
    24121 ttggtacttt aaaatcttta taaacagtga tttgatattt attaatatca ctataattat
    24181 attcacaaga atatccatta tctctgtttt ttccataaaa taaagtcttt atttgaccat
    24241 ccatttcaac atcaacttta aagtaataaa aataaacacc tgtaccatca aacttttcaa
    24301 tcttaccaca aaagcacttt ccaagtttat cattatctaa ttcttcattt aaagttattg
    24361 ttctcatttc ttcttctcta tttatttcta gggaaataga cttgatattg tatccctcat
    24421 ttactttaac acaaatggtc aattcctcat caaattttaa agctccaaac ggagccttaa
    24481 aatttttatc ccaagagtta tattctatta cactttgcat ttaatcacac ccttttaaac
    24541 caaatgtctt ttgcatactc agaaattgtt ctatcagaag aaaaaaatcc agagttagct
    24601 atattaacta aagacatttt attccatttt tctttatctc tatataacct gtttatatct
    24661 gcttgagctt gaccataatt ttcaaaatct ctcaatacaa aatactcatc attgtaagta
    24721 gtgagtgaat tataaatact tcttccttct tcgccaagat taggaataaa tccatttatt
    24781 aaatcatcta ctaccctttt tatatccata ttagaatgat ataggtcaag tgaagaatat
    24841 ccaccatatt tattataatt tagtacttgt tctgcactaa gtccaaataa aaacatattt
    24901 tctttaccaa cctgttcaca tatctctaca tttgcaccgt caagtgtagc caaagttata
    24961 gcaccattca tcataaactt catattactt gttccagatg cttccttagt tgtagttgaa
    25021 atttgctcac taacatttgc tgctggtatt attatttctg ctaatgatac tccataattc
    25081 tctaaaaata ctacttttaa cttgtccttt actctaacat cattatttat agtacttgca
    25141 acagaattta taaatttaat tatacattta gccaaataat atcctggtgc tgcttttgcg
    25201 ccaaatataa aagttcttgg gtcaagattc aaattaggat tatcaagtaa ttcatgatac
    25261 atatgaagta cattaaatat attcagtaac tgtcttttat acgcatgcaa tctcttaact
    25321 tgaacatcaa atatcgaact tgggtctaca tttaaatcgt atttatcttt tataaacttt
    25381 gctagatttg ctttattatt gtattttata tcatcaagtc tttgtaaaac agaggaatca
    25441 tttttaaatt tttcaatatt ttttaattgt aatgtatctt tcttccatga atcaccaatt
    25501 aaatctgtaa ttaaattgct aagttgagga tttgaactta taagccatcg cctatgtgca
    25561 attccattag tcttattatt aaatttattt ggttcatctt gatagaaatc ttttaatacc
    25621 tctgtttcaa gaatatgagt atgaagctta gcaactccat ttacactatg acttgtgaca
    25681 atacataagt ttgccatatt gatattgtca cagtctatta tactcattct ttttattcta
    25741 tcttggtcat atcctttatt atttaattcc tctacatatc ttctatttat ttcttctatt
    25801 atcatataaa ttcttggtaa tagctctttc atcatactta caggccattt ttccattgct
    25861 tctgacatta tagtatgatt agtataggac actgtttttt tagttatttc ccatgcttca
    25921 tcccaagata aattttcttc atcaagcaaa attctcataa gttctggtat gcataaggta
    25981 ggatgtgtat catttatatg aattgctacc ttatcgaata aattattaat atttaatttg
    26041 ttctttttat attttcttat tatatcttgt atccctgcac ttacaaaaaa gtattcttgt
    26101 ttcaacctca acaacttacc tgcatagttt gaatcatcag gatataatac ctgtgatatt
    26161 tcctcagtat aatacttatg ttttaaagcc tcttcatagc taccagaata atttagagca
    26221 tttgaggtaa gttcaccaaa atctctcttt ggtatttcac tcttaaacaa tcttaaagta
    26281 tttatacatt ggttttggta tccgattatt ggtatatcat aaggcattgc cattacagga
    26341 aggtagtttt tatgaattac ttttaaatga ctaccttcct tgattaattc tacctcacca
    26401 ccaaacttca ccattgttgc ttcatttggt cttacagttt cccatgcata tcgtccttct
    26461 gtaagccagt tatcaggcac ttctacctga taaccattta caaatttttg ttcaaacaga
    26521 ccatatttat accttattcc atatccttga ccacttatgt tcaaagatgc catagaatct
    26581 aaaaagcaag ctgctaatct accaagtcca ccatttccta aggctgggtc tacttcagtt
    26641 tcaattaaat catccaagtt gattcctaat tcagataaac cttctctaac ttcttcttca
    26701 atatttaaat ttaataaatt agattttaac tgtctcccta ttaaaaattc taaactaaaa
    26761 taataaactt cttttttctt atctaacttt gtagcaaccc atttttttgc tatctcatct
    26821 ttcaatagac tacataatac atttaacaat tgttcatcag tagcttcctt gatagattgt
    26881 gcatataagc tatacatttt tacttcaaat ttttgcttga atttcttttt gcttattgtt
    26941 accaaaaaaa ccactccttt aatcacatat gtctctatat gtttctatat actccttagc
    27001 tgattttttc caactattat ctgttttcat tgcattttca actaatttaa tccatttttc
    27061 tttgtcctta aatactttga ttgcattttt caaacagaaa aacatctcat gagcattgta
    27121 atttttaaaa ctaaatccat tgccttctcc agtaaattta ttataaggtg ttactgtatc
    27181 tctaagccct ccagtctctc taactattgg taaagaacca tatctcatag ctaacatttg
    27241 acctatacca caaggctcaa ataatgatgg cattaagaac atatcacttg cagcatatat
    27301 ctgttgagcc aatgatgcat taaaagtaat tctagctgat actttatctg aaaaattaga
    27361 atcgtaatag ttgaacattg attgatattg atgttctcca gttcctaaaa cgacaatctg
    27421 taaatcttct ctcataagtt ctggcatcat gtatgctatt aaatcaaatc ctttttgaga
    27481 aactaatctc gaaactatac ctatcaacgg aatagatgaa tcttttttaa gtcccaatat
    27541 atcttgtaat ctcaatttat tttctacttt tttgtcaatt gagtctacat cataatgaac
    27601 aaatatatct ttatcttttg cagggtcatt taaatcataa tctataccat ttaatatacc
    27661 ttttaatttt cctgactctt ttctaagtaa tccatctaat tgttcaccat aaaaagatgt
    27721 ttgtatttca tttgcataag taggactaac agttataatt ttatctgcaa aatttatacc
    27781 agctttcata aaatttattg agccataata ctctatatct ccattatcaa agtatttttg
    27841 tggtaagtcc aatatatcat ataaaacatg cttatcaaat acaccttgat attggagatt
    27901 atgtatagta tacatagttt ttatattttt atacccctca agggttgcat atctttcttt
    27961 tagaattaat ggtaacatcc ctgtatgcca atcatttata tgtattacat ctggataaaa
    28021 atcaattcta cttatagctt ctaaaactgc atctgtaaag aaagtatatc tttctgcatc
    28081 atctccatat ccatagatac tctttctttc atcttctctt ctaaaataaa attcattatc
    28141 tataaagtaa aattttacac catctaattc catttctaaa agaccacagt attgatttct
    28201 ccatccaaca cgtacactaa acacagctat ttcttttagt tgatctttta aataacttgg
    28261 tatagttgaa tatttgggca ttattaccct tacatctaca ccttcttttt ttaattcttt
    28321 aggcaatgca taagaaacat ctcctaatcc tccagttttt gcaaagggcc aacactctgc
    28381 tgttacataa aaaaccttca ttagtcattc ccccttctaa aaaatttatt tatatatttg
    28441 tattcttttc cactacaaga ggatattttt catctcctct taattctttc ccatttgata
    28501 cactcgtatt tttatctaat attgcattat atagttttgc atttgacttt attacacaat
    28561 tttgcattac tattgagttc tctataactg ttcctttttc aacatttacc tttctaaata
    28621 tgatactatc ttttacagta ccttctatta aacaaccaga tgctataaag ctattttcta
    28681 ctttagcact atctgtataa attgtaggtg attcattctt ttcttttgta aatatctttc
    28741 tttcagaata taataattca tctgcaactt ctaaatttaa taaatctttg ctcatttcaa
    28801 aatatgattc aacagaattt acacatttta gatatcctgt atattcatag gctcctattt
    28861 tcatattttc tgcttcttca ataataaatt cttctaaata acaataattg cctttattta
    28921 caatgttata tatacattca acaaaatctt cacgcttcat aatatatgtc tccatacata
    28981 tgtttgctct agggaactta cctaaattat ttcctacatt tattacccta ttgttactat
    29041 ctaaatttag agttaagtta ccagcaaaat ctttatttgc attatttaca tttttatata
    29101 ttatagttat atcattatga gattttttat ggtattccaa tgcttgagaa taatttaaat
    29161 tgcatagcat atagcttgga gctattaaaa tatattcttc ttcactcttt tctatataat
    29221 ctagattagc taagatagta tatatatcac cttctctatg tgagtaagta tttctatact
    29281 tagtgttttc tggactaaaa attgataggc cacctttttt tctacttaaa tcccaatctt
    29341 taccactacc tatatggtct gttaatgatc tgtatttttc ttttgcgaat attccaactt
    29401 tagtgattcc tgaatttatc atattagata aagcaaagtc tattattcta tatcttccag
    29461 ctattggtgt agatgctatt ggtcttccat agttaagttt gtttattgct gggtctcctt
    29521 ttttgtttaa atttattatc cctaaacatt catttctcat cttaaagacc tccttctatt
    29581 aatacgcatc taggttcgat attttcatac tcagaaacta catttatttc attatttaca
    29641 ttctttatct gaacattatc atttatagtt gcacactcac ctatcatagc tttttctata
    29701 gttacatttt cacctattac aacatttggc attattactg aatcaattac tttacttcct
    29761 ttaccaacaa caactccatg tgataataca gagttaccta cttcacctaa aattctacaa
    29821 ccatcagcta tcattgatct atgaacattt gcatttttac ctatatattg tggaggcatt
    29881 gccatagtat ttgtatatat cttccactta gggtctgcta aatcaagtgt ttctggagat
    29941 tttattatat ccatattagc atcccataga ctttgtatag ttcctacatc tctccagtat
    30001 cctttaaatg gataagcata cattccaaca ttatcttcta acattttagg tattaaattt
    30061 tttccaaaat catcataatt tatttctgga tttttttctg cttccttaaa ataatttctc
    30121 aacattttcc aatcaaatat gtatactccc atagatgcca aattgctctt aggttcactt
    30181 ggtttttctt caaattcata gatacttgaa tcttcatttg tattcattat cccaaatctt
    30241 gaagcttcat cccaaggaac ttcaatcact gctattgtag ctttagagcc tttttcctta
    30301 tgaaatttta acattttgct ataatccatc ttgtatatat ggtcaccaga taatatcaat
    30361 acatattctg gattataggt atctacaaag tccatatttt gatatatcgc atgtgctgta
    30421 ccattatacc aatttccttc tttttcattc ataaatggtt gtaaaacata gacaccacca
    30481 tttattctgt ccaaatccca atgacttccc atgcctatat gtgaatttaa tatcaacggt
    30541 ctatattgag ttaaaacacc tacagtatca ataccagagt ttgaacaatt gcttaacaca
    30601 aaatctataa ttctatactt acctccaaat gatacagctg gtttggcaat tctttttgta
    30661 aaaacaccta atcttgaacc ttgccctcct gccaaaatca tagctaacat ctcttttttc
    30721 atttaatgac actcccctca tctagtaatt aatatttata attgcatttt tacttttata
    30781 aactttatca gtcaataaat gtcgtgtata aatgttgctt aaataatacc ttaataaaaa
    30841 taaaataata tcaactatac aattgatata atgtataccc cataatggac ttaccgacgt
    30901 atacattatt ttccataagc actatagtat ttattaatat tcaattattg gttaaaaaat
    30961 aatacaaatt ttattttata aatataaaaa cattttttat aaatcctttg tgtcatatga
    31021 acatgcttat tttttaat
//
LOCUS       DAEPKC010000041        30652 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.041, whole genome shotgun sequence.
ACCESSION   DAEPKC010000041 DAEPKC010000000
VERSION     DAEPKC010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 30652)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30652)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30652
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.041"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(70..888)
                     /locus_tag="KR294_001905"
     CDS             complement(70..888)
                     /locus_tag="KR294_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sporulation protein YtxC"
                     /protein_id="HBH0239985.1"
                     /translation="MVEKDNISSMKFLRNNNVNDRLIYTNDIVEVVIDSAKQEVLNKK
                     ILNGTKAEQRALNIDEISTEITSMIISIMKEKLLKEYILKCYGRTYPEDKNNIYIYSL
                     NIFAKKEIFMRETVFTRVRNYIEENDFINVEGFIRFRMREFMKYISAIGDIAVEEYLI
                     KKDQDEFIRVLKYFIDTQEEKIDLLKVHIMEDNTFVLYDKNGNKIDSIDDEEIINMVI
                     RENLNYEDFLISTLLTLCPKKIEILDLLNNNCSKEIIDTVEAIFENKVSIIMEN"
     gene            complement(891..1652)
                     /locus_tag="KR294_001906"
     CDS             complement(891..1652)
                     /locus_tag="KR294_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0239986.1"
                     /translation="MEFTREPFILDDDLCLALVDKRISYLMENELKLRNIEIIKTIEC
                     KELYESIKYHPDICICNLGKGDIIVAPNVYNQYKELLSRYKFNIIKGEANLLNRYPYD
                     IPYNIAIVGDYAIHNFKYTDKAILDYIENNKLKKINIEQGYSKCSICIVDRTSIITSD
                     KGIWKSMKNTEIECLLIEKGHINLFEMNYGFIGGCTGLISKDKLAFCGDVKKHPDYER
                     IKSFVESKNKEIVTLSCENLLDIGSIVPLMTRKER"
     gene            complement(2142..3254)
                     /locus_tag="KR294_001907"
     CDS             complement(2142..3254)
                     /locus_tag="KR294_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HBH0239987.1"
                     /translation="MKIKRILMACFVVVFTIFILAICNFDFGFDKVNKNNSNIDSAKS
                     KQSESKSLPTSAEKDKSNSKSKNKEDDTEDDSYVRKTIGVLLDTENLNNESYNNNVLS
                     ALKRADEDFDVRIKLEKPKTSKSFKESIEKLHKYEPDLIIAVGARFAEPIKEAATEYP
                     KQQFAIVDYTYKVQPANVISVSFQDNVTGYLAGLIAGKMTDTGKVGFIGGVEGSSRDK
                     YESGFRKGLKTSNKDAELLVKYSNIFENPESARTIAKEMRDSDRDVVFSATEDDSKRA
                     IQVARENGGKVIAINKDQYDMAPDNVISSIIKDVEQPVYELIKNVAKDGFKGSKVMEF
                     KIKDGELGLTSKSSRNIPPDVLEYIKKEYNKVKDTY"
     gene            complement(3380..4384)
                     /locus_tag="KR294_001908"
     CDS             complement(3380..4384)
                     /locus_tag="KR294_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HBH0239988.1"
                     /translation="MRFKRILILMLTVAMIAGMLVGCANNPSNNPSSSKDNKSDISDK
                     SNSKKSVSMILDIEGTNNEAMNNSALLALNNAQKKLNIDTNKVESDDSSTFSNSIDIL
                     CNDNYDLIIAVGARFAKPLEMVAKKYPKQQFAIIDYEYDKQPSNITSISYEDNKSGYL
                     AGLIAGKMTESDKVGFIGGTKSSSRDKFESGFREGVKFSNSSIKDISVEYADVFKDSK
                     SVESIAKKMMDNGVDIIFSTTEDDSKAVIDAVRAKNKKVIATNKDQHELAPENVISSI
                     VKDFENPTYNLIQSFVKGNYKGGKVIENTVKSGSTGLAQNSSQNIPPDVLEYVNKNNK
                     "
     gene            complement(4689..5537)
                     /locus_tag="KR294_001909"
     CDS             complement(4689..5537)
                     /locus_tag="KR294_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBH0239989.1"
                     /translation="MKNLKIICDSLSDVPKDLLDKYDIDIVSLTVILEEREYKDRIDI
                     SGDEFYKKLREENVYPKTSQATYAQFKEIFEKYTNEDREILYIAGSATATGTYQSAVM
                     AKNDVDGKIYTYDSNLLCMGTGLLVIKAGELASEGKSVAEILPVLDELKEKAFVIFSV
                     DTLEYLQKGGRISSTKAAIGSILNIKPILEIRDGLVSQISQVRGKKNVISKMMELIKS
                     NCGDDLSDQIVYIGYSDDFKEKEQLSKVMQDELRPKEIRFFQIGVCIGAHAGPGVTGI
                     ICLKNK"
     gene            complement(5573..6043)
                     /gene="trmL"
                     /locus_tag="KR294_001910"
     CDS             complement(5573..6043)
                     /gene="trmL"
                     /locus_tag="KR294_001910"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HBH0239990.1"
                     /translation="MSLNIVLVEPEIPQNTGNIIRTCAATGSTLHLVKPLGFSLDDKH
                     LKRCGLDYWDIADIQYYDSFEELQEKYPNSKYFFSTTKAKQSHSDVKYEENCFIVFGK
                     ETKGLPEPLLKANMDTCIRVPMLDVEKARSLNLSNSVAIVVYEALRQIGYPNMR"
     gene            complement(6237..7454)
                     /gene="nth"
                     /locus_tag="KR294_001911"
     CDS             complement(6237..7454)
                     /gene="nth"
                     /locus_tag="KR294_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HBH0239991.1"
                     /translation="MKNVNLKEINEKDVILEEEINKKGMDKKNIIEKEEINKKGIDKK
                     DIIEKEEINKKGIDKKDIIEKKEINKKGIDKKDIIEKKEINKKEMDKKDIIEKEEINK
                     KGMNKKDIIEKEEINEKEIDKMIGKKDEIIDEKDIENFMDIEEDKKSIKVSKKSTKKG
                     ETEKKTKKSSSNKATQKTSKETKSKFKIKNESANEKDVNKILDELEKLYPDAKCELNY
                     GTAFELLIATILSAQCTDVRVNKVTSELFKKYNTARDFANLSIEEISKEIKSCGLYKS
                     KSQKIKDTSEQLCELYDGEVPDSLEKLIKLPGVGRKTAGVVLSNAFNHPAIAVDTHVF
                     RVSNRIGIVDEPNPQKTEFALMEAIPKERWSHSHHVLIFHGRRMCKARNPECASCPIK
                     EDCNYYKELNETK"
     gene            complement(7652..9889)
                     /locus_tag="KR294_001912"
     CDS             complement(7652..9889)
                     /locus_tag="KR294_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBH0239992.1"
                     /translation="MKYNNTSEINPLDYILGQERAVEAMELGLKINNPAYNIYIAGEP
                     GTGKSTYALKVLNEYASKKNTHKDWCYIYNFENPREPIIVELEKGFGRELKKDMEKLI
                     ESLLEDFKNAFESENFEIEKNKLLDEYEIEKDMLLKQIKKYGEEKGFKLKQSKMGIVF
                     IPLKEEEDESDESDEEFYKAKRELENMAIQVVYKIRNLEEIAEKAVLELEEEIAKLVV
                     EPHIKRLCEKYENYDKIQTYLENIKKDIIEYMYLFYLDEEELKDKYDKEHFIKYKINL
                     FVDNGSSKNKESAPVVVEINPSPANLFGKAEYDYANGNIKTDFTKLLSGAFHRANGGY
                     LVLYADQLLKYTMSWEILKKTLQTKKVILETQTAIKPENMPLDVKLVLIGSHYIYDIL
                     YRYDEDFEKYFKVFVDFDSEMDKNEDNEEGIARFIAYQCDKNNLRHFTKSAVEEVIKF
                     STRLSGDLEKLSTKFNKIMEVVIEGSAYAEFRNSEYTKQCDVKKAISEKRKRINRVET
                     HMDESIENGFTLIETEGRKVGVINGLSVLSTGEYSFGRASRITATTSPGSKGIVNIER
                     EVNMSGSIHNKGVLILGGYLSENFAQDLLLSLNAYVCFEQNYGGIDGDSASSAELYVL
                     LSSLSGVSIKQNIAVTGSINQKGDIQVVGGISEKIEGFYSICKTKGLNGEQGVIIPRK
                     NQRNLVLSDEVNDAVRDGKFKIYTVERVEEAIEILTDVKFEEIKKLVKEKLISFSKIQ
                     TVSKE"
     gene            complement(9995..10909)
                     /gene="queG"
                     /locus_tag="KR294_001913"
     CDS             complement(9995..10909)
                     /gene="queG"
                     /locus_tag="KR294_001913"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HBH0239993.1"
                     /translation="MDNKELKAFCNLIGLNCVGVAGVDKYDNLEKILKNRQQKGYLTG
                     MEEPIIESRINPRHIMKDANSIIVCAFPYHINRQEKNKNSNLSKYCHGKDYHIVVKDF
                     LQQICDYISKTVTDFKYKLFADNGPLVDRYLAYLSGIGYFGINNNIITDEYGSYVFIG
                     YIVNNYKFEEDKPLEKSCFKCGKCVKYCPGNAILGNYDMNPKKCLSYITQKKGDLSEK
                     EKVVLKNGKKVFGCDICQEVCPHNVEIPTTHILEFKENIIDYLDYDEIQNISNKEFKR
                     RYGDRAFSWRGRNIIKRNMEIILDKYDD"
     gene            11750..12154
                     /locus_tag="KR294_001914"
     CDS             11750..12154
                     /locus_tag="KR294_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HBH0239994.1"
                     /translation="MIKITIPGRPISKSNFKLHNINGQAWMPSKGKYSKYLAYENMIA
                     GFINQQYQGETVEENLITVLKLFFPNKRMGDLHNYPKSICDGIEKSGIIKNDKQLKPV
                     LLFDFIDKDNPRVEIELYPVSKYDISYNIFEK"
     gene            complement(12411..13406)
                     /locus_tag="KR294_001915"
     CDS             complement(12411..13406)
                     /locus_tag="KR294_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBH0239995.1"
                     /translation="MRNLGNTNMKIKRVGFGGIPIQRITQDDTNLVINELEKQGINFI
                     DSARGYTISEEAIGIAIEGKRDKFFLATKSMSRDYDSMKRDVEISLNNFKTDFIDLYQ
                     FHNVKEEEYDNLFKDKMAYSALLEAKEQGKIKHIGITSHNLNTIEKAIEDGKFDTIQF
                     PYNIVEGQADEVFKKAHEKGIGIIVMKPLAGGALDNATLAIKYILSKDYIDVVIPGME
                     SVEQVRQNVAVLENLVLDEKDNKEIEEIRNSLGKKFCRRCEYCMPCAVGINIPLSFLC
                     EGYYTRYGLKEWAKEKYEVMDVKPTECIDCGLCESRCPYELPIREMLKTVVEKLG"
     gene            complement(13690..14526)
                     /locus_tag="KR294_001916"
     CDS             complement(13690..14526)
                     /locus_tag="KR294_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HBH0239996.1"
                     /translation="MIKLGTHLSIAKGFANAAETAVYIGANTFQFFSRNPRGGNAKEF
                     DEKDIIKFQEIRKENNFAPLLAHAPYTMNLGGTKDDVYEFATRVIDEDIRRMDSLGIE
                     YMCFHPGSHVGGGVDFGIDRIVKGLNNAIKGDENITILLETMSGKGTEIGFKFEQLKS
                     IIDKIEHKEKIGVCLDTCHIFSAGYDIVNDLDGVLEEFDKVIGIERLKTVHLNDSMMP
                     FGDKKDRHAPIGEGKIGLKALIDFMEHPSLKHLPFFLETPFDDEGHKKELKMIKEILS
                     SK"
     gene            complement(15014..15577)
                     /locus_tag="KR294_001917"
     CDS             complement(15014..15577)
                     /locus_tag="KR294_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0239997.1"
                     /translation="MKEVLVLRDLECIKAIAHPRRIDILKAFDKSPLSAKQLSQLLEE
                     PHAKINYHIKMLYKVGILELVEEKIKSGIVEKYYYPSAKNVVIGNRILNFSLDNGEEK
                     EELYISKFENMSEVFYKAAEEDVLENENIVDYHDISLTHDELVELSDTMKSKIDEILN
                     KRQHNVEGSKYDIAMVIVPTLEEECPS"
     gene            complement(15675..16604)
                     /gene="glsA"
                     /locus_tag="KR294_001918"
     CDS             complement(15675..16604)
                     /gene="glsA"
                     /locus_tag="KR294_001918"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HBH0239998.1"
                     /translation="MNTLDETLLKEIISSNKKYTNYGQVASYIPELKNARRNDLGICI
                     IDSENNLYSAGNCSTKFTIQSISKPIVLAMALMDNDWEDVFSNVGMEPSGDPFNSIMK
                     LEINDTKKPCNPMINAGAIVTTSLINGSCLEEKEERMLSFFRKLAKNDNIGINYDVYK
                     SEKMTGDRNRAMAYLLKSDGFIRGNVEDVLDLYFKQCSIEIDSVDLARIGINLANYGV
                     DIENGEHLMSEMVSRIVKTFMMTCGMYDASGEFAIKVGIPAKSGVGGGIMASVPGRMG
                     IGVYGPALDKKGNSVAGVKVLEELSNKLKLNIF"
     gene            complement(17145..18812)
                     /locus_tag="KR294_001919"
     CDS             complement(17145..18812)
                     /locus_tag="KR294_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside kinase"
                     /protein_id="HBH0239999.1"
                     /translation="MKKINLKIEGKDKEYSLEENSPGIRLGDIAKEFCDEHKGYITLA
                     VVDNKLKELNCRVKKDCEINFLDTTNEDGERVYFRVMSFIFVMACREIFWDSRVTIEH
                     SLSDGLYCEVHIDRKLKEADVENIKNKMKEIVNNDYVIEKIEVTRNEAISIFENNEMY
                     EKAELLKYKEYDSAKVYKCRNYIDHFYGYMLPSTGYIKSFDIKLYNGGVIILGPSEED
                     KTLPMKFVPQPKLSSVYYEAEEWSRLMGIDKVVSLNKIIENNEYGDIIRTFEALHEKK
                     LSQIADMIKDGNKRVVLIAAPSSSGKTSFAHRLSIHLRVNNLNPISISLDDYFIDRKH
                     TPLDEYGNYDFESIYAIDLEKFNLDLKKLLAGEEIDDIRFNFKEGKREYTGKKIKIDS
                     NQPIILEGIHGLNPILTSSIPDEDKFKIYISALTQINLDDHNRIPTADLRMIRRIVRD
                     YNFRGYSADNTILQWASVRRGEKKNIFPYQEEADAIFNSACVYELAVLKRFAKPLLEE
                     IKEDNPAHIEATRLLKFLQYFVELDDTSDIPGISILREFIGGSKIVD"
     gene            complement(18886..19641)
                     /locus_tag="KR294_001920"
     CDS             complement(18886..19641)
                     /locus_tag="KR294_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM barrel protein"
                     /protein_id="HBH0240000.1"
                     /translation="MAVGIASLLFNIEEALNICESIKQITHLEIGIDNISECSELCKY
                     KERISKLGLSIGIHLPMELNTCENIEYIRNSWINFIEKIEFELKGFDLRYFNLHLGYV
                     MTNRVRKNRDKYLGNSVDFLDKLNTNSYVCIENTYSKGGDFSNIGNISYDFEYIFKRI
                     KNSKICFCYDTGHCLIDEDAYVKNLKDKIRLIHLSDNDGINDTHVGIGRGILSEEGIK
                     EVLTLDAEYLVLEINYEDIEDTISKLNNIVGEG"
     gene            complement(19651..20187)
                     /gene="lepB"
                     /locus_tag="KR294_001921"
     CDS             complement(19651..20187)
                     /gene="lepB"
                     /locus_tag="KR294_001921"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBH0240001.1"
                     /translation="MNETIKEEIVEWIKIIITALFFAFIITRFIKPTLVNGESMYPTL
                     KSHDYLVANRMTYKLSEPKCGDIMIFKTDLLQENGRKKELVKRVIGVPGDHLKIKDSK
                     VYINGKLLNEVSYIHDNYTEGDIDMVIPKGKVFAMGDNREVSLDSRYKEVGLVDEENI
                     KGKVILRVFPFTDIGIFE"
     gene            complement(20353..20889)
                     /gene="lepB"
                     /locus_tag="KR294_001922"
     CDS             complement(20353..20889)
                     /gene="lepB"
                     /locus_tag="KR294_001922"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBH0240002.1"
                     /translation="MGEAVKKEVVEWIKVIVIALVLAFAITRFIVPTIVKGESMYPTL
                     VERDYLIVNRIAYKVGEPKYKDIIVFKTDLTEENGKKKDLVKRVIGVPGDHVKIQDSK
                     VYVNDKLLDETSYIHNNRTDGDIDIVVPEGKLFAMGDNREKSLDSRYDEVGLVDEHTI
                     LGKVLVRLYPFSKIGTID"
     gene            complement(20989..22299)
                     /locus_tag="KR294_001923"
     CDS             complement(20989..22299)
                     /locus_tag="KR294_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmB/NOP family class I SAM-dependent RNA
                     methyltransferase"
                     /protein_id="HBH0240003.1"
                     /translation="MTELPNEFLEDIEEILKDEYDDFIKSYEESKTTGLRINTLKIDK
                     KKLFDLELFDLNQIPWAEEGFYYDDKIDRPGRNPLHEAGAYYLQEPSAMSVIPKADIK
                     EGEKVLDMCAAPGGKSTYILSKLNDTGLLVSNEINASRIKALGENLERFGARNCIITN
                     TDSNSLRKTFNGYFDKVIIDAPCSGQGMFRKDEVAISDWSYAKVVECQSIQKEIIRDG
                     YKMLKKDGILIYSTCTFSREENEHVINEFISEYPHAELIEMERLWPHKIKGEGHFVAK
                     IKKLEEEECNVKELKIKNLDKEIKDYREFEKKFLKVDFYSNKKNKFYLRGENLYLLPE
                     IYPDTKKLKVLRYGLHLGVLKKNRFEPSHALSHYLKVEDVKNVENFSVQSESILKYLK
                     GDVVNSNDSRGWVLVSVEGIPLGWGKESSGVIKNHYPKGLRKVF"
     gene            complement(22378..23094)
                     /locus_tag="KR294_001924"
     CDS             complement(22378..23094)
                     /locus_tag="KR294_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HBH0240004.1"
                     /translation="MKLDLFLLAIVPILIGMFWIRSKDRYCREPLIHLIKFFLIGAFL
                     SVIIILLENLLMKFNVFEGYSELIYVSFVVAGLVEEGVKALILIPALIKEKHFTEKLD
                     GIIYSVFLALGFATIENMVYIFSESRNLALQVGINRAVISIPAHVMFAITMGYYISKY
                     KFEGNKNKRREYLFMAVLIPILLHGVFDFILMIEYRWAIILLIVYVIILWKINLDKLE
                     KYMNHSKKVFFGNLRKKKKK"
     gene            23339..24610
                     /gene="sleC"
                     /locus_tag="KR294_001925"
     CDS             23339..24610
                     /gene="sleC"
                     /locus_tag="KR294_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore cortex-lytic protein SleC"
                     /protein_id="HBH0240005.1"
                     /translation="MQDGFLTVSIIDATNNRPIQNAVVNIYSMSNGSQSSSTLYQNLR
                     SNESGQVTGLVLPAPDVDYSLQPSDVRPYSQYIVEAIADGYETVVIEGTQLLATIEAR
                     QGVPMSPRTRSKRSFSRQSELIFDIGEHTLYGTYPPKIPESNLKPLPPPTGFVVLDNP
                     VVPEFIVVHDGLPEDSSAPNYWIPFKEYIKNIASSEIYSTWPEQTIYANVIAIISFTL
                     NRVFTEWYRNKGYNFTITSTTAYDHKFINNRNLFEPINVVVDAIFNTFIKRPPTSRQP
                     LLAQYCDGQKSQCPDQMTQWGSKDLGDQGYDYESILRYFYGDEIVFERAPIVSGVPVS
                     FPGTTLQVGSSGQYVRTIQNQLNAISNSYPAVPKVIEDGIYGTDTENAVKIFQGIFGL
                     PQSGVVDFKTWYEISRVYVATTRIASLNPLI"
     gene            complement(25118..25774)
                     /locus_tag="KR294_001926"
     CDS             complement(25118..25774)
                     /locus_tag="KR294_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240006.1"
                     /translation="MKKGDFIWSGVLICIIAVLAIPSSREVFMEATGAHPYIGGFLKF
                     AVLATMGDLLGARILYKDWKIPVGVFYRAIVWGIIGVVTTYGMSIYSSGVGQAQVDGM
                     LPFEGIAFANALFKSATMNILMSPTVFLFHKVMDCFIDKKYEVGKGIKVKLKDVVNIV
                     DWNAYLGFSVLKTIPFFWIPCHTIVFLFPAEYRVIASAFASIALGLILALANKSKVAV
                     "
     gene            complement(27046..27456)
                     /locus_tag="KR294_001927"
     CDS             complement(27046..27456)
                     /locus_tag="KR294_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240007.1"
                     /translation="MKIKKSLISAMMVSAMVLGGTGAVFANGNDSSNIALPKLESLIK
                     SGITDPTELEKYGVEHYTYEEYAKHIQELKDYAKDPNAVKDVSQKDLEETIKKMEQEL
                     EKIKTEGLKIMKPITIENEDGSQISIAYNYAAID"
     gene            complement(27672..29054)
                     /locus_tag="KR294_001928"
     CDS             complement(27672..29054)
                     /locus_tag="KR294_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HBH0240008.1"
                     /translation="MFIKLLEMSFTSGVLLLIVIFIRACLFKKLPKKVFVLLWLIVLF
                     KLLIPVSLNSGFSIYSIIESTFDVELGNTSTENYTLKKASDSTGKNNSDEFEIMSNIE
                     NIMMLEMLGILSFIVTIMFSILLCFRYFKIINLFKTSIHIKNHEFIKKWMCKNSRFRR
                     FIVCISEFTRTPLTSGILKPRIILPKQMNYANNQTLDFVLTHEMVHINSFDNLLKLFM
                     LVALVVHWFNPLVWVMFFLLNKDIEFSCDEKVMSILGEEYRADYATTLISLAEENNPF
                     SMTICSGFGKTKIEKRIVNIMKFKKSTYVTFLVSTVLVCGTGLVFATENKEINEVESF
                     GLTKNEQSDKIGFSISSKSTDLYSPKVESDILVSKAKSDGETHFSTAKVSVIEFREHE
                     ESSMSKVTNSENSEETYVNKSSNGKDVLYTDSGEVSIEQSGYNDNRFVISRKGNLLAV
                     NKEQYRTWIE"
     gene            complement(29065..29424)
                     /locus_tag="KR294_001929"
     CDS             complement(29065..29424)
                     /locus_tag="KR294_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBH0240009.1"
                     /translation="MEIKLFDSELKVMEVLWERGESKAGELVKILKEETGWNRNTTYT
                     VIKKLVSKGAIERIEPNFVCKALISKEEVQKQETETLINKMFGGSSEKFLSAFINKEN
                     LSSDEITKLKQIVEKLK"
     gene            complement(29629..30408)
                     /locus_tag="KR294_001930"
     CDS             complement(29629..30408)
                     /locus_tag="KR294_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HBH0240010.1"
                     /translation="MVSRQELKRVSKAQLSGNWGICAISMAVYIALIVLISIVGLPFE
                     PLTTIVVAVIAFCVSAGFTCMFLKITKDEKVKIGDIFVSGRIYLRSFGFYLFESIIVY
                     IYSFIITIIGAFLSFGVLLTSGAIEYLSSDNVGIGTVISTGITLVLIILVLMLPVYIL
                     LLYVSQATFLICEDKDNMGVFKSMGASLDMMKGNVLKLFVLNFSFIGWYILSIATLGI
                     GLLWLIPYVGVTNCNFYRQLVKENPDVEDILLDKEKSYTMY"
BASE COUNT         9922 a         5614 c         2878 g        12238 t
ORIGIN      
        1 taagtctttt gtgtcgattt aaaaagaatt tttttaattt tatatggata gcttttatat
       61 gcttagattc tagttttcca taattatact aactttattt tcaaaaattg cttctacagt
      121 atctataatt tcctttgagc aattattatt taacaaatcc aatatttcta tttttttggg
      181 acatagagtt aataaggtac ttattaaaaa gtcctcataa tttaaatttt ctcttattac
      241 catatttata atttcttcat catctatact gtctatctta tttccatttt tatcgtataa
      301 aacaaatgta ttatcttcca ttatatgaac tttaagcaaa tcaatctttt cttcttgagt
      361 atctataaag tattttaaaa ctcttataaa ttcatcttgg tctttcttta ttaaatactc
      421 ctcaactgca atatcaccta tagcagaaat atatttcata aattctctca ttctaaatct
      481 aataaaacct tctacattta taaaatcatt ttcttctata taatttctca ccctagtaaa
      541 tactgtttct ctcataaaaa tctctttttt agcaaatatg ttcagtgaat atatgtatat
      601 attattttta tcttcaggat atgtacgccc atagcatttt agaatgtatt ctttcaaaag
      661 tttctctttc attatactta ttatcatact agttatttcc gttgatatct catcaatatt
      721 taaagctctt tgttcagctt tagtaccatt aagtattttt ttatttaaca cttcttgctt
      781 tgcagaatct atcactactt ctacaatgtc attcgtatat attaatctat cgtttacatt
      841 attattcctc aaaaatttca tggaagaaat attatccttc tcaaccaaag ttatcgctcc
      901 tttcttgtca tgagaggaac tatagaacct atatctagta aattttcaca gctaagtgta
      961 actatctcct tgtttttact ttctacaaaa ctttttatac gttcatagtc aggatgtttt
     1021 ttaacatctc cacaaaaagc tagtttatcc ttagaaatca accctgtaca tccacctata
     1081 aatccataat tcatctcaaa taaatttatg tgaccttttt ctatcaataa acactctatt
     1141 tctgtattct tcatactttt ccaaatacct ttatctgatg ttattataga cgttctatct
     1201 actatacaga ttgagcattt agaatagccc tgctctatat ttatcttttt aagtttatta
     1261 ttttcaatat aatctaatat tgctttgtca gtatacttaa aattgtgtat agcatagtca
     1321 ccaactatcg caatattgta aggtatatca taagggtatc tatttaataa attagcttct
     1381 cccttaatta tattaaattt atatctactt aataactctt tgtattgatt atatacattc
     1441 ggcgcaacaa ttatatctcc ttttcctaaa ttacaaatac atatatccgg gtgatatttt
     1501 atgctttcat ataattcttt acattctatt gtttttatta tctctatatt tcttaatttt
     1561 aattcatttt ccattagata actaattctt ttgtccacca aagctagaca caaatcgtca
     1621 tctagtataa atggttctct tgtaaattcc attttttact cctttttctt ttttttgata
     1681 aattttttat gtgaatataa ataaagtgtg tagcagaatt tttctgccca cacacttatt
     1741 gttataattt tatatagtta atctaagctt aattagtata gctttgtaca gttggttcaa
     1801 atttaataaa tatatctttt tatcactaat ctaaacttaa gcagtatatt ccgtacagtt
     1861 agcacaaatt taataaatat atctttttat tgctaatcta aactcaatca atatattttg
     1921 tacagttaga ctaaatttaa taaatatatc cttttatcac caatctaaac ttaagcagta
     1981 tattccatac tgttaacaca aatttaataa atatatcttt ttatcactaa tctaaactta
     2041 atcaatatat tttgtacagt tagcacaaat ttaataaata tatcctttta tcaccaatct
     2101 aaacttaagc agtatatttt tataatcttc tacatcaata attaatatgt atctttcact
     2161 ttgttatact ctttttttat gtattccaaa acatctggtg gtatatttct actgctcttt
     2221 gaagtcaagc caagttctcc atcttttatt ttaaattcca ttactttact tcccttaaaa
     2281 ccatcttttg caacgttctt tatcagttca tatacaggtt gttctacatc ttttataatt
     2341 gaacttatta cattatctgg agccatatcg tattggtctt tattaatagc tataacttta
     2401 cctccatttt ctcttgctac ctgaatagct cttttactat catcctctgt agctgaaaat
     2461 acaacatctc tatcagaatc tctcatttcc tttgcaatag ttctagctga ttcagggttt
     2521 tcaaatatat ttgaatactt aactagtaac tcagcatctt tatttgaagt tttaagcccc
     2581 tttctaaatc cagattcata cttatctcta ctagaaccct caactcctcc tataaaacca
     2641 accttcccag tatcagtcat tttacctgca ataagtcctg ctaaatatcc agtaacatta
     2701 tcttgaaatg atacagaaat tacattagct ggctgaactt tataagtata gtcaactatt
     2761 gcaaattgct gtttgggata ttcagtagca gcttctttaa ttggctctgc aaatctggct
     2821 ccaactgcta ttatcaaatc tggttcatac ttatgcagtt tttctatact ctctttaaaa
     2881 cttttagaag tctttggttt ttcaagtttt atcctaacat caaaatcttc gtcagccctt
     2941 tttaaggctg atagtacatt gttattatat gattcgttat ttaagttttc ggtatctaac
     3001 aatactccaa tagtttttct tacatatgaa tcatcttctg tgtcatcttc tttattctta
     3061 cttttactat ttgatttatc cttttctgct gaagttggca aacttttaga ctcactctgt
     3121 ttcgatttag cactatctat attagaatta ttcttattta ctttatcaaa cccaaaatca
     3181 aaattacata tagctaatat aaaaattgta aaaactacta caaagcaagc catcaatatc
     3241 ctttttattt tcacaaaatt cactccctga tttagatagg tctgacctac ctctgcatat
     3301 gtctttctat atatgtctat tataacatcc aattcacctc ataactaaag tcataagtat
     3361 tcttggatat tatagtagat tatttattgt tcttattaac atattctaac acatctggag
     3421 gaatattttg agaactattt tgggcaagcc cagtacttcc agacttaact gtgttttcta
     3481 taacttttcc gcctttataa tttcctttta caaaactttg tatcagatta taagtaggat
     3541 tctcaaaatc ttttacaata gaacttataa cattttctgg agctaactca tgttggtctt
     3601 tattcgttgc tataactttt ttattttttg cccttactgc atctattaca gcttttgaat
     3661 catcttcagt agtagaaaaa ataatatcca ctccattatc catcattttt ttagctatag
     3721 attctactga tttgctatct ttaaaaacat ctgcatactc aactgaaata tcctttatac
     3781 tactattaga aaatttaaca ccctctctaa aacctgattc aaatttatct ctactagaac
     3841 tctttgttcc tcctataaaa ccaaccttat cgctttcagt catttttcca gcaattaatc
     3901 cagctagata tccagattta ttatcttcat aagaaattga agttatatta gaaggttgct
     3961 tgtcatactc atagtctata attgcaaatt gttgctttgg atatttcttg gctaccatct
     4021 ccaatggttt tgcaaatcta gctcctacag ctataattaa atcgtaattg tcattacata
     4081 aaatatctat actattagaa aaagttgagg aatcatctga ttccactttg tttgtatcta
     4141 tattaagttt cttttgagca ttgtttaatg ctaataaagc tgaattattc atagcttcat
     4201 tatttgttcc ttcaatatct agtatcattg atacagattt ttttgaatta cttttatcgc
     4261 ttatatcact tttattatct ttgctagagc taggattatt gcttgggtta ttagcacacc
     4321 caaccaacat tccagctatc attgctacag ttaacatcaa tatcaatatt cttttgaaac
     4381 gcattaaatt tcactcctca tacatttacg atatttttat atcctattta cttttacatc
     4441 ctatttactt ttacatccta tttataattt ttttatatac aatttacaag tacattttga
     4501 aattttttta ataaatctta ctataaaaaa gtgtgcaata gattcttatc tatttacaca
     4561 cttccctaca aactaaatct aatatatcaa cacttaattt catccaaaat aaatccaatt
     4621 taacatctca ataattaata ttctatccta atttaataaa aaaataaata atgtcatcca
     4681 aaaatatatt atttattttt taagcatatg ataccagtaa caccaggacc agcatgtgca
     4741 cctatacaca caccaatttg gaaaaatcta atttctttag gtcttaattc atcttgcata
     4801 accttagata attgttcttt ttccttaaaa tcatcactat atcctatata tacaatttgg
     4861 tctgataaat catcaccaca atttgatttt atcaattcca tcatcttaga aattacattc
     4921 ttctttcctc ttacttgaga tatttgcgaa actaatccat ctcttatttc aagaatcggt
     4981 tttatattta atatacttcc tattgctgcc ttagtagatg atattctacc tcccttttgt
     5041 aaatattcca atgtatctac tgaaaatata acaaaagcct tctcttttaa ttcatccaaa
     5101 acaggcaata tttcagcaac agactttcct tcacttgcaa gttctcctgc ttttattaca
     5161 agtaaaccag ttcccataca aagcaagtta gagtcatatg tatatatttt accatctaca
     5221 tcattctttg ccattacagc actttgatac gtacctgtag ctgtggcaga ccctgctata
     5281 taaagtatct ctctatcctc atttgtatat ttctcaaaaa tttccttaaa ttgggcataa
     5341 gtagcttgag aagtttttgg atatacattt tcttctctaa gctttttata aaattcatct
     5401 ccagatatat caattctatc cttgtattct ctttcctcca gtataactgt taatgaaact
     5461 atatctatat catatttatc taacaaatct tttggcacgt ccgataaact gtcacagatt
     5521 atctttagat ttttcattaa gtatgctcct ttctcattta ggcttgttga aactacctca
     5581 tatttgggta tcctatttgt cttaaagcct cgtacactac aatagcaact gaatttgata
     5641 aatttaatga cctagctttt tcaacatcca acataggcac tctaatacaa gtatccatat
     5701 ttgctttcaa caaaggttct ggtaatccct ttgtttcttt cccaaatact ataaaacaat
     5761 tttcttcata tttcacatct gaatgtgact gtttagcctt tgttgtagaa aaaaagtatt
     5821 tactatttgg atacttttct tgtaattctt caaagctatc gtaatattgt atatcagcta
     5881 tatcccaata gtcaagccca catcttttta ggtgtttatc atccaatgaa aaacccagtg
     5941 gttttactaa atgtaaagtt gaacctgttg ctgcacaggt tcttattata tttcctgtat
     6001 tttgaggtat ttctggttct actaatacta tatttaatga cattttaatc ctccctaagt
     6061 atcgctttta tttatcaaat tttattttat aaacagaata acaataatat tatactatta
     6121 tataaaataa tgttaataat aatttttatt tcatgtatat aatagttttt tatctaacat
     6181 tttcacaagt attattatat cagaaaatcc ctcttgtaca acttactttc taaaagttat
     6241 ttcgtttcat taagttcttt ataataatta caatcttctt ttattgggca acttgcacat
     6301 tctggatttc tagctttaca cattcttctt ccatgaaaaa ttaatacatg atgtgagtgt
     6361 gaccatcttt cttttggtat agcttccata agtgcaaatt ctgttttttg aggatttggc
     6421 tcgtccacta ttcctattct attgctaact ctaaatacat gagtatctac agctattgct
     6481 ggatgattaa aagcgttact aagtacaacc cctgccgttt ttcttccaac accaggtaat
     6541 tttataagct tttctaagct atcaggtact tcaccatcat ataattcaca tagctgttca
     6601 gatgtatcct ttattttttg agacttgctt ttgtaaagac cacaactctt tatctcttta
     6661 ctaatttctt caatgctcaa attagcaaag tctctagctg tgttgtactt tttaaacaac
     6721 tctgaagtaa ctttattcac tcttacatca gtacattgtg ctgataaaat agttgctatt
     6781 aaaagttcaa aggctgtccc ataatttaac tcacatttag catctgggta cagtttttct
     6841 aactcgtcta aaatcttatt tacgtctttt tcatttgctg actcattttt aattttaaac
     6901 ttacttttag tttctttact tgttttttgt gtagccttat tagaactact cttctttgtt
     6961 tttttctccg tttcaccttt tttagtactt tttttactta ctttgatact ttttttatct
     7021 tcttcaatat ccataaaatt ctctatatct ttctcatcaa ttatctcatc ttttttacca
     7081 atcattttat ctatttcttt ttcatttatc tcttccttct caattatatc tttcttattc
     7141 attccttttt tatttatctc ttccttctca attatatctt tcttatccat ttctttttta
     7201 tttatctctt tcttctcaat tatatctttc ttatctattc cttttttatt tatctctttc
     7261 ttctcaatta tatctttctt atctattcct tttttattta tctcttcctt ctcaattata
     7321 tctttcttat ctattccttt tttatttatc tcttccttct caattatatt tttcttatcc
     7381 attccttttt tatttatctc ttcttccaaa attacatctt tttcatttat ctcttttaga
     7441 tttacatttt tcataattat cccccttcaa aataccaatt tataaaacgc tatttataaa
     7501 tagtttaatc atatcaacaa aaaaataaac atcaatatat aaaacataca aaataagaat
     7561 ttaatttata tatatttaca aaaaaagcaa aaacctatta aagttcttgc tttttattat
     7621 acataaatac ccattaaatt ctataataaa cttattcttt tgacacagtt tgtatcttgc
     7681 tgaaagatat taatttttct tttaccaatt tctttatttc ttcaaattta acatctgtca
     7741 atatctctat agcctcttct actctttcaa cagtatatat cttaaatttt ccatctcgca
     7801 ctgcatcatt aacttcatct gataaaacga gatttctttg attttttcta ggaattatga
     7861 cgccttgctc accatttaac cctttagttt tacatataga ataaaatcct tctatctttt
     7921 cacttatacc accaactact tgtatatcac ccttttgatt tatagaacct gtaacagcaa
     7981 tattttgttt aattgatact ccactaagag atgataatag tacatataat tctgcagaag
     8041 atgcactatc tccatctatt ccaccataat tttgttcaaa acaaacatat gcatttagtg
     8101 acaatagtaa atcctgtgca aaattctcag aaagatagcc acctaatata agtactcctt
     8161 tgttatgtat agagccactc atatttactt ctctttctat atttactatg cctttacttc
     8221 ctgggctagt ggtcgctgta atccttgaag ctctaccaaa agagtattct cctgtactta
     8281 agactgacaa accatttatc actcctactt ttcttccctc tgtttctatt agagtaaatc
     8341 cattttcaat tgattcatcc atatgtgttt ccactctatt gattcttttt ctcttttcac
     8401 ttattgcttt tttaacatca cactgctttg tatactccga atttctaaac tctgcataag
     8461 cacttccttc tattacaact tccattattt tattaaactt agttgataat ttttctaaat
     8521 caccagataa tctagtgcta aatttaataa cctcttcaac tgctgattta gtaaaatgcc
     8581 ttaaattatt cttatcacat tggtatgcta taaatcttgc tattccttct tcattatctt
     8641 catttttatc catttcacta tcaaagtcta caaatacttt aaaatatttt tcaaaatctt
     8701 catcatatct atataaaata tcatatatat agtggcttcc aatcagtact aatttaacat
     8761 ccaatggcat attttctggt ttaattgctg tttgtgtttc caatattact tttttagtct
     8821 gcaaagtctt tttaagaatt tcccaagaca ttgtatattt tagtaattgg tctgcataaa
     8881 gtactaaata accaccatta gccctatgaa atgctcctga taatagtttt gtgaaatcag
     8941 tctttatatt tccatttgca taatcatact ctgcctttcc aaatagattt gctggacttg
     9001 ggtttatctc tactacaaca ggtgctgatt ctttattctt tgagcttcca ttgtctacaa
     9061 ataggttaat tttatattta ataaaatgct ctttatcata cttatctttt aactcctctt
     9121 catctaaata gaataaatac atatattcta ttatatcttt ctttatattt tccagataag
     9181 tttgaatctt atcataattt tcatattttt cacacaatct cttgatatga ggttctacta
     9241 caagtttagc tatctcttct tcaagctcta acactgcttt ttcagctatt tcttctaagt
     9301 ttctaatttt atatacgacc tgtatcgcca tattttctag ttctctttta gctttgtaaa
     9361 actcttcatc agactcatca ctttcatctt cctcttcttt caaagggata aaaactattc
     9421 ccattttact ctgttttaat ttaaatcctt tttcttctcc atatttttta atttgcttca
     9481 aaagcatatc tttttctatt tcatattcat ccagaagttt atttttttct atttcaaaat
     9541 tttcactttc aaacgcattt ttaaaatctt ctaaaagact ttcaattaat ttctccatat
     9601 ctttcttaag ttctcttcca aacccctttt ctaattcaac tataataggc tctctagggt
     9661 tttcaaaatt atatatataa caccaatctt tatgcgtatt ttttttggat gcatactcat
     9721 ttaaaacctt taaggcataa gtacttttac cagttccagg ttcaccagct atatatatgt
     9781 tgtacgctgg attatttatt ttcaacccta attccatagc ttctacagct ctttcttgac
     9841 ccaatatata atctagtgga tttatttcag atgtattatt atatttcaat attcccccac
     9901 ctccccatat ttaactttaa tgatataata tgacttttac acaacaagtg ttaaagtaaa
     9961 tacacattaa agtatatgaa acagactctt attattagtc atcatactta tctaaaatta
    10021 tttccatatt tctctttatt atatttctac ctctccagct aaaagctcta tctccatatc
    10081 tccttttaaa ttctttattt gaaatatttt gtatctcatc ataatccaaa taatctatta
    10141 tattttcttt aaattccaaa atatgagttg ttggtatttc aacattatgt ggacatactt
    10201 cttgacaaat atcgcatcca aatacctttt tgccattctt taaaacaact ttttctttct
    10261 ctgacaaatc tccttttttt tgagttatat atgataaaca ttttttgggg ttcatatcat
    10321 aatttcccaa tatagcattt cccggacaat attttacaca cttaccacat ttaaaacaac
    10381 ttttttctag tggtttatct tcttcaaatt tataattatt tactatatac cctataaata
    10441 cgtaagaacc atattcatca gttatgatat tattatttat tccaaaatat cctattcctg
    10501 ataaataagc taaatacctg tcaactaatg gtccattatc agcaaataac ttgtatttaa
    10561 aatctgttac tgttttagaa atataatcac aaatttgttg taaaaagtcc tttactacaa
    10621 tgtgataatc ctttccatga caatattttg ataaatttga atttttattc ttttcttgtc
    10681 tatttatatg atatggaaat gcacagacta ttatagagtt agcatccttc attatatgtc
    10741 ttgggttaat tctgctctca attattggtt cttccatacc agttaaataa cctttttgtt
    10801 gtctgttctt aagtatcttt tctaaattat catatttatc tacccctgct actcctacac
    10861 agtttaatcc tattaaatta caaaatgctt ttaattcctt attatccata aaattattcc
    10921 tttttaatct aattgacttt ttaaatttat ttaatttttt tagtcttttt aaccttttct
    10981 agctactaac tcttttaaat acttaatctt tttagctatt caattttctt acctgcttaa
    11041 ctcttttaga tacttcgtct ttttatctat ttaatttttt tacctactaa ctcttttagg
    11101 tacttcgtct ttttacctat ttaatttttt acctactaac tcttttagat acttcatctt
    11161 tttacctatt tagtttttta cctactaact cttttagata cttcatcttt tttatttact
    11221 tatttaactt ttttacctac taactctttt agatacttag cctttttcat ttacttattt
    11281 aactttttta cctacttaac tcttttagat acttagcctt tttaatctat tcaacctttt
    11341 ttacccactt aaccttctta ccttttaata taaactctaa aacttcaaat atcattagtt
    11401 atattttgac attctttcta tagttaagca aaaagattga ttttttctta taattaatat
    11461 cccatttaca ttgccattta ttaagtcttt acttgactta tatggatttc tttttactct
    11521 ctttactaaa cttatactta ttaatattat gaaggtctta taatagtcta atatgaatat
    11581 gcccatcata tatcaaattt taaaatttgt aagcaaaata cttatcttat attactacat
    11641 ctaaagtgga aaattttaca aacaagctct gtaaaaacac tttaaataac aatttgcttt
    11701 taaatcatat acagattata ataaatactg tataaggatg gtgaaaaatt tgattaaaat
    11761 aacaattcca ggtagaccta ttagtaaatc taattttaag cttcataaca taaatggtca
    11821 agcatggatg ccttcaaagg gaaaatattc taagtatctt gcatacgaaa acatgattgc
    11881 aggttttata aaccaacagt atcaagggga aactgttgaa gaaaatctaa taacagtctt
    11941 gaaattattc ttcccaaata agagaatggg ggatttacat aattatccaa aaagtatttg
    12001 tgatggtatt gaaaaaagtg gaataataaa aaatgataaa caacttaagc cagtactttt
    12061 atttgatttt atagataaag ataaccctag ggttgaaatt gaactttatc cagtatctaa
    12121 atacgatata tcctataata tttttgaaaa ataaagattt tatgtgttat tcgacattat
    12181 attgatactc cagtatttga aactatacta atacaacaat aataattgtg ttatgtctat
    12241 actcaaacaa atgtttttaa aaagcattaa gtaaatattt aataagtatt aaacaaatat
    12301 taaatttata taatagctat aactatgtaa atttaatatt tgtatataag accacatcta
    12361 ataaaaagaa atcggagtaa atttaataca ccgatttcaa taaataaaat ctatcctagc
    12421 ttttcaacaa cagtcttaag catttctctt ataggaagtt catatggaca tctactctcg
    12481 caaagcccac agtcaataca ctcagtaggt ttaacatcca taacctcata tttttcttta
    12541 gcccactctt ttaatccata tctagtataa taaccttcac ataaaaaact caatggtata
    12601 tttattccta cagcacaagg catacaatat tcgcatcttc tacagaattt tttacctaaa
    12661 gaatttctta tttcttcaat ttccttatta tctttttcat ctagcacaag attttcaagt
    12721 acagcgacat tttgtctaac ctgttcaaca ctctccatac ctggtataac tacatctatg
    12781 taatctttag atagtatata tttaatagcc agtgttgcat tgtctaaagc acctccagct
    12841 aaaggtttca ttactattat cccaattcct ttttcatgag cttttttaaa cacttcatct
    12901 gcttgtcctt caactatatt gtaagggaat tgtatagtgt caaattttcc atcttctata
    12961 gctttttcta tagtatttaa attgtgacta gttataccaa tatgttttat cttaccttgc
    13021 tcctttgcct ctaaaagggc actataagcc attttatctt taaaaagatt atcatactcc
    13081 tcttctttaa cattatggaa ttgatataaa tctataaaat cagttttaaa attatttaaa
    13141 cttatttcaa catctctctt cattgaatca taatctctgg acatactttt agtagctaag
    13201 aaaaatttat ctctttttcc ttcaatggca attccgattg cttcctcact tattgtatac
    13261 cctcttgcac tatcaataaa gtttattcct tgtttttcta actcatttat aactaagtta
    13321 gtatcatctt gagtaatcct ttgtattgga atgcccccaa agccaactct ctttattttc
    13381 atgttagtat tgcctaaatt tctcatatct ttccccacct aacttttaat aattttttat
    13441 ataatataaa tatgtcatct ttaattatac aacaaattat gagaatcttt gcaatatatt
    13501 tacatactat tcatagtata attatatttt atatcagtct attcataata taatcatact
    13561 ttatacccag ttaatttgta tacaattttt gttattccta tccattaatt taaattatca
    13621 catttcatga ttgtatctcc accctaatta tgttgagggt gaagtatttc acatattttt
    13681 aataaaggtt tatttactag atagtatttc ttttatcatt ttaagctctt tcttgtgacc
    13741 ttcatcatca aaaggagttt ctaagaaaaa tggtaaatgt tttagactag gatgttccat
    13801 aaaatcaatt aatgctttta atcctatctt tccttcccct ataggagcat gtctgtcttt
    13861 tttatctcca aatggcatca tactatcatt tagatggaca gttttcaatc tttctatgcc
    13921 tataacctta tcaaattctt ccaaaacccc atctaaatca ttcactatat cataaccagc
    13981 tgaaaaaata tgacatgtat caagacacac acctattttt tctttatgct caattttgtc
    14041 tattatactt tttaattgct caaatttaaa acctatttca gttccctttc ccgacatagt
    14101 ttcaagaagt atagttatat tttcatcacc ctttatggca ttgttcaatc cttttactat
    14161 tctatctatg ccaaaatcta caccaccacc tacatgactt ccaggatgaa aacacatgta
    14221 ttcaattcct aatgagtcca tccttcttat atcctcatct atcacccttg ttgcaaattc
    14281 gtatacatca tcctttgtac cacccagatt catagtatat ggtgcatgtg caagcagtgg
    14341 tgcaaaatta ttttcttttc taatttcttg aaatttaatt atatcttttt catcaaattc
    14401 tttagcattt cctcctcttg gatttctact aaaaaattga aatgtatttg caccaatata
    14461 tacagctgtc tcagccgcat tagcaaagcc ttttgctatt gaaagatgtg ttcctaattt
    14521 aatcatatta atctcctttt atttgtacta cgacttgtac tcaattttaa ttttgaacta
    14581 ctccacctta actacattta gccaacatat gaagatggag attcctattt gatagtactt
    14641 tttcactaaa aattcgtaag ctctaaggga tgttctatcc caactaatct cattcctctt
    14701 ttaacatatt tctagcattg atttaattta tattaatttt taattttaat atttacactt
    14761 taattatacc cattttaatc aatttcaaat attataatct tacatacttt gtatattatc
    14821 taagcacttc ttagatagtg tatacatctt acactataca tattatttac aaatacaata
    14881 ggtataaaaa aacaaaaaaa tagagattaa aaatcattgt tttacccata ccaaaaacta
    14941 ttttttgatt attaagtaaa ttttgatgtt caatctctaa tattatatct ttaattaatc
    15001 cataattaat tctctaacta ggacattcct cctcaagagt aggaactata accatagcta
    15061 tatcatactt agaaccttca acattgtgtt gtcttttatt taaaatttca tctatctttg
    15121 acttcatagt gtcactaagt tcaactaatt catcatgagt aagagaaata tcatgataat
    15181 caactatatt ttcattttct aaaacatctt cctctgctgc cttataaaaa acttcactca
    15241 tattttcaaa ttttgatatg tacaattctt ctttttcttc cccattgtct aaagaaaaat
    15301 taagtatcct attccctata accacatttt ttgcacttgg ataatagtac ttttccacaa
    15361 tccccgactt tattttttcc tcaactaatt ctaaaatacc aactttgtat aacattttta
    15421 tatggtagtt tatttttgca tgaggttctt ccaataattg agataattgt tttgctgaca
    15481 atggcgattt gtcaaatgct tttagaatat ctattctacg tggatgcgca atagccttta
    15541 tgcactccaa atctcgtaat accaatacct ctttcattga cccctcctaa aaaatttatt
    15601 taattcatat ttctttacaa tttaattata tattaaatta tatgttgttg tcaaaaaaat
    15661 cctttcttaa tattttaaaa aatatttaat ttgagtttat ttgacaactc ctctaaaact
    15721 ttaactcctg cgacgctgtt accttttttg tcaagcgcag gtccataaac accaatcccc
    15781 atgcgtcccg gcacagaagc cattatacca cccccaactc cagattttgc aggaatgcca
    15841 actttaatag caaattcccc agaagcatca tacattccac aagtcatcat aaatgtcttg
    15901 acaatcctag aaaccatttc actcattaaa tgctcaccat tttctatatc tactccataa
    15961 tttgcaagat ttattccaat tctcgctaaa tctacagaat ctatctcaat tgagcattgt
    16021 ttaaaataaa ggtctagaac atcttctaca ttccctctga taaatccatc acttttcaat
    16081 aagtaagcca tagctctgtt tctatctcca gtcatttttt cagacttata gacatcatag
    16141 tttattccta tattatcatt ttttgctaac tttctaaaga aactaagcat tctttcttct
    16201 ttttcttcta aacaactccc atttataagg gaagtggtta ctatagcccc tgcatttatc
    16261 attggattac agggtttttt tgtgtcatta atttcaagtt tcattattga attaaatggg
    16321 tccccacttg gctccattcc aacgtttgaa aaaacgtctt cccaatcatt atccataagt
    16381 gccatagcaa gcacaattgg ttttgaaata ctttgtatag taaactttgt gctacagttt
    16441 ccagcactat aaagattatt ttcgctatct atgatacaaa ttcctaaatc atttcttcta
    16501 gcgtttttta attctggtat gtaactagcg acttgtccat aattagtata cttcttatta
    16561 gaacttataa tttcttttaa taatgtctca tctaacgtat tcatatgcac ctcttatatt
    16621 atgttatata ttctatttta gcacaagttt atactataat aaaacaatgt taaaaaaaat
    16681 tatactttaa aattattttc tacaagaatc aattcatttt tcaaacaatt taaatagttt
    16741 aaagagctta ataatttagt aattcaataa tttaacaacc tagtaattta gcaatccagc
    16801 aatctaataa tccagtaatt taaattttta tgacaccaaa aatttctaac ccaacacctt
    16861 ttactctttt actcttttac tcttttactc ttttactctt ttactctttt actcttttaa
    16921 aaaataatca cataaactaa caaaatatta aacaaaaaag taaaatttaa aataaaaagc
    16981 ttgcttcata caaaagtata aaacaagcct ttttatatat caactcaaac tttaaaatct
    17041 gtatcaattt aattctccac tttacactta atatacttaa cataaaccaa taacactact
    17101 tgctatgcca tttaatcttc ataaaacaat ctataataca cacattaatc aactatttta
    17161 cttcctccaa taaattccct aagaattgaa atacctggta tgtcagaagt atcgtccaat
    17221 tcaacaaaat actgcaaaaa ctttagtaat ctagtagctt caatatgtgc aggattatct
    17281 tcctttatct cttccaacaa aggtttcgca aatcgtttta aaactgccaa ttcatataca
    17341 caagcagagt taaatatagc atctgcctcc tcttggtacg ggaatatatt cttcttttct
    17401 cctcttctaa ctgatgccca ttgtaaaata gtattatcag cactatatcc tctaaaatta
    17461 tagtctctaa caattcttct tatcattctc aaatcagcag tagggattcg attatggtca
    17521 tccaaattta tttgagtaag ggcacttatg tatatcttaa atttatcttc atctggtata
    17581 gatgatgtta aaataggatt tagcccatgt ataccttcta atataattgg ctgatttgaa
    17641 tctatcttta tctttttacc agtgtattct ctcttacctt ctttaaaatt gaatcttata
    17701 tcatcaattt cttcaccagc taaaagtttc tttaagtcta agttaaactt ctctaaatct
    17761 attgcataaa ttgattcaaa atcataattt ccatattcat ctaaaggagt atgttttcta
    17821 tctataaaat aatcatctaa agaaattgaa ataggattta aattatttac tctaagatgt
    17881 attgataatc tgtgagcaaa acttgttttt ccagatgaag atggagctgc tattaaaact
    17941 actctcttat tgccatcctt tatcatatcc gctatttgag atagcttctt ttcatgcaat
    18001 gcttcaaatg tccttattat atctccatat tcattgtttt ctattatttt attaagagat
    18061 actaccttgt caattcccat aagtcttgac cattcttctg cttcataata tacacttgat
    18121 agcttaggtt gaggtacaaa tttcatagga agagtcttat cttcttcact aggtcctaaa
    18181 attataacgc ctccattata aagcttaata tcaaatgatt ttatataacc agttgatggc
    18241 aacatataac cataaaaatg gtctatatag tttctacact tatatacttt agcactatca
    18301 tactctttgt atttcaaaag ctctgccttt tcatacattt cattattttc aaagatagaa
    18361 atagcttcat ttcttgtaac ttcaattttt tctataacat aatcgttgtt tactatctct
    18421 ttcatcttgt tttttatatt ttcaacatct gcttctttaa gctttctatc tatatgaact
    18481 tcacaatata gcccatctga tagtgaatgt tctattgtaa ctctgctatc ccaaaagatt
    18541 tctctacatg ccattacaaa tataaatgac atgactctaa agtaaactct ctctccatct
    18601 tcattagtag tatctaaaaa atttatctca caatccttct taactctaca atttagctct
    18661 tttagtttat tgtctacaac tgcaagtgtt atataaccct tatgctcatc acaaaattct
    18721 tttgctatat ctcccaatct gattccaggg gaattttctt ctaatgaata ttccttatct
    18781 tttccttcta tttttaagtt tatttttttc acttcaacat ctccttcctt ttgatgaata
    18841 taaattttaa ttaatgaggc atatcaacaa gataaagaga ggtatttaac cctctcctac
    18901 aatattattc aatttactta tagtatcttc aatgtcttcg taatttattt ctaatactaa
    18961 atattctgca tctaatgtta agacctcttt aatcccctct tcagataaaa ttcctcttcc
    19021 tataccaaca tgtgtatcat tgataccatc attatcactt aagtgtatca gtcttatttt
    19081 atcctttaag ttctttacat aagcatcctc atcaattaaa cagtgtccag tatcgtaaca
    19141 aaaacaaatc ttagaatttt taatcctctt aaatatatat tcaaaatcat aagatatatt
    19201 tccaatattt gaaaaatccc caccttttga ataagtattc tctatacata catatgaatt
    19261 tgtatttaat ttatctaaaa aatccacact atttcctaaa tatttgtctc tattctttct
    19321 aactctattt gtcataacat atcccaaatg aaggttaaaa taccttaaat caaatccttt
    19381 tagttcaaat tctatcttct caataaaatt tatccatgaa tttcgtatat actctatgtt
    19441 ttcgcaagta tttaattcca taggcaagtg tatccctata gataatccta acttagaaat
    19501 tctctcttta tatttacata actcactaca ttcagatata ttgtcaattc caatctctaa
    19561 atgagttatt tgctttatac tctcacaaat gtttaaagcc tcctcaatat taaacaataa
    19621 ggacgctata ccaactgcca tacaaatcac ctactcaaaa atacctatat ctgtaaaagg
    19681 aaatactctt aaaataactt ttcctttaat attttcttca tctactaatc ccacttcttt
    19741 atatctactg tctaaactaa cttctctatt gtctcccatc gcaaatactt ttcccttagg
    19801 aatcaccata tcaatatcgc cttcagtata attatcatgt atatatgaaa cttcatttaa
    19861 taacttacca tttatataaa ccttagaatc cttaattttt agatggtcac caggaacacc
    19921 tataaccctt tttacaagct cttttttcct tccattctct tgtaataaat cagtcttaaa
    19981 tatcattata tctccacatt ttggttctga taacttatat gtcatcctgt ttgctaccaa
    20041 ataatcatgt gatttaagtg ttgggtacat tgattctcca tttactaatg ttggttttat
    20101 aaaacgagtt ataataaatg caaaaaaaag tgcagtaata attattttta tccactctac
    20161 aatctcttct ttaatagttt cattcattca caaattctcc tttatagtta tattatcttt
    20221 attgataatg tctcttaaac actatctttt agataagtct actaaataag gtgttgtctt
    20281 ttttatatag acaactattg tgtatggtct ggtgatttca gctaatcagc gattgctcca
    20341 aattttatat gtttagtcaa tagttcctat cttagaaaat ggatacaatc tgactagaac
    20401 ctttcctaaa atggtatgct cgtcgaccaa tccaacctca tcgtatctac tatctaaact
    20461 tttttctcta ttatctccca ttgcaaataa ttttccttct ggaactacga tatcaatatc
    20521 tccatcagta cgattattat gtatatagga agtctcatct aacaacttat catttacata
    20581 taccttggag tcttgtattt ttacatggtc accaggaaca cctataactc tttttactaa
    20641 atcttttttc tttccatttt cctctgttaa gtcggttttg aatactatta tatctttgta
    20701 ttttggctct cctaccttgt acgcaattct gttaactatc aaataatcac gttcaactaa
    20761 tgtaggatac attgattctc ctttgactat tgttggcact ataaaacgag ttattgcaaa
    20821 tgccaaaaca agagctatga caatcacttt tatccattct acaacttctt ttttaactgc
    20881 ttcacccact aaaatcgtct cctctgtgtt aaatattaag tcaatctaca gcaaaataat
    20941 ctaccataaa cctacaatat aaatattata cttctttttt ctaatagttt aaaatacttt
    21001 tctaagacct ttaggataat gattcttaat tacaccagaa gattcttttc cccaacctaa
    21061 aggtattcct tcaaccgaaa ccaaaaccca tcctctacta tcattagaat ttacaacatc
    21121 cccttttaaa tatttaagaa ttgattcact ctgtacactg aagttttcaa cattttttac
    21181 atcttcaact tttaagtaat gagatagtgc atgagaaggc tcaaatctat tcttctttaa
    21241 aacccctaaa tgcaaaccat atctcaatac ttttagtttt ttcgtatctg gatatatttc
    21301 aggaagtagg tacaaatttt ctcctcttaa ataaaattta ttttttttat tactataaaa
    21361 atcaaccttt aaaaatttct tttcaaactc cctataatcc tttatttctt tatctaaatt
    21421 ttttattttt aattctttga cattacattc ttcttcttct aattttttta ttttggcaac
    21481 aaaatgacct tctcccttta tcttatgagg ccataatctt tccatttcaa taagttctgc
    21541 atgtggatat tcactgataa actcatttat aacatgctca ttttcctccc ttgaaaaagt
    21601 acaagttgag taaattaaaa tgccatcctt ctttaacatt ttatatccat ctcttataat
    21661 ctctttttgg atggattgac attctactac ctttgcataa ctccaatctg atatggcaac
    21721 ctcatccttc ctaaacatac cttgcccaga acaaggtgca tctataataa ccttatcaaa
    21781 atacccatta aacgtctttc ttaagctatt agaatcggtg tttgttataa tacaatttct
    21841 cgctccaaat cgctctaaat tttcccctag agccttaatt ctactagcat taatttcatt
    21901 agaaaccaat aaacctgtat cgtttagctt agatagtata tatgtagatt ttccaccagg
    21961 agcagcacac atatcgagaa ctttttcacc ctctttaata tctgcctttg gtattacact
    22021 cattgcagaa ggctcttgca aatagtatgc tccagcctca tgcagtggat ttctaccagg
    22081 tctgtcaatt ttatcatcat aataaaaacc ttcttctgcc catggtattt gattcaaatc
    22141 aaacaactcc aaatcaaata attttttctt gtcaattttt aaagtattta ttctaagccc
    22201 agtagtctta ctttcctcat aactttttat aaaatcatca tattcatctt ttagtatttc
    22261 ttcaatatct tctaaaaatt catttggtaa ttctgtcaaa tctataatcc cccttcaatc
    22321 tgctttactt gtgtgtcatt tattatactt taattattta tgtctttcct ttaaatttta
    22381 tttcttcttc tttttcctaa gattaccgaa aaacactttt ttagagtgat tcatatattt
    22441 ctcaagttta tcaagattta tcttccacaa aattattaca taaactataa gtaatataat
    22501 agcccatcta tattctatca tcaatatgaa atcaaaaact ccatgtaata aaattggaat
    22561 taacactgcc ataaacaaat actcacgtct tttattttta tttccctcaa atttatactt
    22621 agaaatatag tagcccatag taattgcaaa cattacatga gctggtatag agataactgc
    22681 cctattaata ccaacttgca gtgctagatt tctactttca gaaaaaatat aaaccatatt
    22741 ttcaattgtt gcaaatccta aagctaaaaa tacagagtaa ataataccat ctaacttttc
    22801 agtaaagtgt ttttctttaa ttagggcagg aatcagtatc agagctttta caccttcttc
    22861 tacaagtcct gcaactacaa atgatacata tattagttct gaataccctt caaatacatt
    22921 aaacttcatc agtaaatttt ctaaaagtat aattataaca cttagaaaag cacctattaa
    22981 aaaaaattta attagatgga ttaggggttc tctacaatat ctatctttag accttatcca
    23041 aaacattcct atcaatatag gaactattgc taataaaaat aaatctagct tcatagatta
    23101 ttttcctttc aaaatttttg atttatttat gatttatatc atctacttat ttttaactta
    23161 ttcgtgtttt aaatacatac taaaatatac attaaattat tttaaattat ttaaatacaa
    23221 atatactcaa atactcaaaa aaatttaaat ttatatctat attatttaac aaattttaag
    23281 ctatattcat atcttgaaat ataagggaac taaattcatt taaagaaagg gtgatttgat
    23341 gcaagatggt ttcttaacag taagcataat tgatgctact aacaatagac ctattcaaaa
    23401 tgcagtagta aacatatatt caatgtctaa tggtagccaa agctcatcaa ctttatacca
    23461 aaacctaaga agtaatgaat ctggtcaagt gactggttta gtattaccag caccagatgt
    23521 agattactct ctacaaccat ctgatgttag accttatagc cagtatatag tggaagccat
    23581 agcagatgga tatgagacag ttgtcataga aggaacacag ttgttagcta caattgaagc
    23641 aagacaagga gttcccatgt ctcctagaac aagaagtaag cgttctttct caagacaaag
    23701 tgagttgatt tttgacatag gagaacatac tctatatggt acttatcctc ctaagattcc
    23761 agaaagtaac ttaaaaccat taccacctcc tactggtttc gttgtattag ataaccctgt
    23821 agtgcctgaa tttatagtag ttcatgatgg tttgccagaa gattcatcag ctccaaacta
    23881 ttggattcca tttaaagagt acattaaaaa catagcatca tctgaaatat attcaacttg
    23941 gcctgaacag acaatttatg caaatgtaat agctataata tcatttactt taaatagagt
    24001 ctttactgaa tggtatagaa ataaaggata taactttaca ataacttcaa caacagcata
    24061 cgaccataag tttataaata atagaaactt atttgaacca attaacgtag ttgtagatgc
    24121 tatttttaat acttttataa aaagacctcc tacatcaaga cagccactat tagcacaata
    24181 ttgtgatgga caaaaatccc aatgtcctga ccaaatgact caatggggca gtaaagactt
    24241 aggtgaccaa ggatatgact atgagagtat actaagatat ttctatggag atgagatagt
    24301 atttgaaaga gcgcctatag taagtggtgt accagtgtca ttccctggta ctacactaca
    24361 agttggttct tctggacagt atgttagaac catacaaaat cagttaaatg ctatatctaa
    24421 ttcttatcca gctgtaccaa aagttataga agatggtatc tatggaacag atacagaaaa
    24481 cgctgttaag atattccaag gaatctttgg tttacctcaa agcggagtag tagattttaa
    24541 aacatggtat gaaatatcca gagtttatgt agctacaact agaatagctt ctttaaatcc
    24601 tttaatttaa agcttgattt agaacataaa ctcaaattat tgaataaaat tattaattta
    24661 aaataaaaat ggctgttatg aactaatata taccataagt attacttata agtattgtag
    24721 tcttaacagc cattttttag ttataacttg tttttttaga atcttaaaac tttaaatggg
    24781 ggattttaag cttcttaaaa acagtgctta gcaacttaga tttctttaaa atattatatt
    24841 tatttttaag tttaataaaa tgctattcta acgaaaaacc tactttttat ttaaaatctc
    24901 acttattatt taaaatgcta cttctcactt agagtattac tccttattat ttaaaacact
    24961 atctatcact tagagtatta cttcttatta tttaaaacac tatccatcac ttagaatatt
    25021 acttcttata taaattatta tttattataa atacaaataa tattaattta aaaagttatt
    25081 cctaatttaa ataatactac tatcttcatc agtgaaccta aactgcaact ttagacttat
    25141 tagctaaagc caatattaga cctaaagcta tagatgcaaa tgcagaagca attactctat
    25201 actcagcagg gaataagaat acaattgtat gacatggtat ccagaaaaat ggtatagttt
    25261 ttaaaacact aaaaccaagg taagcattcc agtccacaat atttaccaca tctttaagtt
    25321 ttaccttaat cccctttcca acctcatatt ttttatctat aaaacagtcc ataaccttat
    25381 ggaataaaaa tacagttggt gacattagta tattcatagt tgcactctta aatagagcat
    25441 ttgcaaaagc tattccctca aatggaagca taccatccac ttgtgcttga cctacacctg
    25501 atgagtagat tgacattcca tatgtggtaa ctacacctat tattccccaa actattgctc
    25561 tataaaatac tcctactggt attttccaat ccttatacaa aattctagca ccaagtaaat
    25621 ctcccattgt agctaataca gcaaacttta aaaaacctcc aatatatgga tgtgcacctg
    25681 ttgcttccat aaatacttct ctactacttg gtattgctaa gacagcaata atacaaataa
    25741 gaactccact ccatataaaa tcgccttttt tcatatttat aaatactatt taatatataa
    25801 atagttctcc tttctattaa agatttattt aatttacaat ctatctacaa ttatttatta
    25861 atcacttatt attagatatt cattttccat atttaaattt attctatccc tttatctatt
    25921 tattttctta ctactctatc caccattatc tatatattta ttttacgatt actctttcac
    25981 cctaaccctt taattatcta ttttttctga tattcttatc taccatcatc catatattta
    26041 ttttacgatt actctttcac cctaaccctt taattatcta ttttttctga tattcttatc
    26101 taccatcatc catatattta ttttacgatt actctttcac cctaaccctt taactatcta
    26161 ttttttctta ctattcttat ccacatcatc catatattta ttttacgatt actctttcac
    26221 tctaaccctt taactatcta ttttttctga tattcttatc caccatcacc catatattta
    26281 ttttacaatt actcttttac cctaaccctt taactatcta tttttttctg gtattcttat
    26341 ctactattat ctgtatattt attttatgat tactctttta acctaccccc tatactttat
    26401 agtaatatgt ttttaacctt tttcattatt cccaatatgc tttataacta caaatactct
    26461 ccccccttaa aaataataat aaaattaatc aataaattta taatcatatt attactctat
    26521 gtattaagca attactatgc caataaactt tgattttttt aaacaaatct taaaaatcct
    26581 aaaatgctaa ttttctttaa cttttaatga atctaataga taacatttaa ttttcgttat
    26641 atttttcaga atatttctat tattattttt aagaaaaaaa aataatgtta acatttctta
    26701 acatacatta aaaaatgtta acattataaa ttgggtttaa tacttttact ttgactcgat
    26761 ttacttttat tctacttctt actttatttt taacttagac tttatttttt tattacttat
    26821 ttgagtctta tttattttat tatcactcca tatgttcaat tacatttgtc taaattcttt
    26881 gatactttta ttacataatt ttaacaagct taagtgttat ttgggtagtg cagttgataa
    26941 ttatttaaat aatcatcaac tgcatgttta tatcattaca gtagcttaat gtatttaatc
    27001 atacttactt aggattttga aatatcttag agattatatt taacattagt caattgctgc
    27061 ataattgtaa gcaattgaaa tttgagaccc atcttcattt tctatagtga taggcttcat
    27121 aatttttaat ccttcagttt ttatcttttc taattcttgt tccattttct taattgtttc
    27181 ctcaaggtct ttttgactta catctttgac tgcattaggg tctttagcat agtcttttaa
    27241 ttcttgaata tgtttagcat actcttcata agtataatgc tcaacaccat acttttccaa
    27301 ttcagtaggg tcagttattc ctgattttat tagagattca agtttaggta aagcaatatt
    27361 agatgaatca tttccatttg caaatactgc tccagttcct cctagtacca ttgcagatac
    27421 catcattgca cttataaggg atttttttat tttcataacc aatcttcctt tcttagagat
    27481 ttatttgggt agtgtagttt gaaatgacta ttgcaatagt tatcaaccac atccttagac
    27541 tatcacagta gtcatgttta tgtcaagcct ttttaaaaaa cttttcaata aaaaatacta
    27601 tctcaaaaca aaattaatta ttttgagata gtattttaat tctaaatctt ttatattact
    27661 aagatttatg gttactctat ccatgttcta tattgttctt tattaactgc taacaaattc
    27721 ccttttcttg atatgacaaa gcgattatca ttatagccac tttgctcaat tgaaacttct
    27781 cctgaatcag tataaagtac atccttacca ttactagatt tatttacata cgtttcttcg
    27841 ctattctcag aattagttac tttgctcata gatgattctt catgctctct aaattcaatt
    27901 acagatactt ttgccgtact aaaatgagtc tctccatcac ttttagcttt actaacaaga
    27961 atatcagatt ctactttggg agaatataaa tcagttgatt tactacttat tgaaaatcca
    28021 attttatcac tttgttcatt ttttgttaaa ccaaaagatt caacctcatt aatctcttta
    28081 ttttctgttg caaaaacaag acctgtccca caaactaata cagttgaaac taaaaaagta
    28141 acataagttg attttttaaa tttcataata ttaactattc tcttttctat ttttgtcttt
    28201 ccaaatccac tacatattgt cattgaaaat ggattattct cctctgctag acttattagt
    28261 gtggttgcat aatcagccct atattcttca ccaagtatac tcataacctt ttcatcacaa
    28321 ctaaattcta tgtctttatt tagtaaaaaa aacatcaccc aaactaaggg attaaaccaa
    28381 tggacaacaa gagctacaag cataaataac tttaacagat tatcaaagct attaatatga
    28441 accatttcat gagttaaaac aaagtctaaa gtttgattat tagcataatt catttgcttt
    28501 ggcaaaataa ttcgtggttt taaaatacca gatgtaagtg gtgtcctagt aaattcagat
    28561 atgcaaacaa taaatcttct aaaacggcta ttcttacaca tccatttttt aatgaactca
    28621 tgatttttta tatgaattga agttttaaaa agattaatta ttttaaaata tctaaagcat
    28681 aaaagtatgc taaacataat agtaactata aaagacaaaa tgcccaacat ttccaacatc
    28741 ataatatttt caatattaga cattatttca aattcgtcag aattgttttt acctgtagag
    28801 tcactagctt tcttaagagt ataattttct gttgatgtat tacccaattc cacatcaaaa
    28861 gtcgattcaa ttatactata aatactaaaa ccagaattta aacttactgg tattagaagt
    28921 ttaaataaaa caatcaacca caataataca aatacctttt taggtaattt tttaaataaa
    28981 catgctctta taaaaataac tattaaaagt aatactccag aagtaaaact catttctaac
    29041 aatttaatga acataaatct tacctcactt taatttttca acaatttgtt taagttttgt
    29101 aatctcatca cttgaaagat tttctttatt aataaaagct gaaagaaatt tttctgaaga
    29161 ccctccaaac attttattaa ttaaagtttc tgtttcctgt ttttgtactt cctctttgct
    29221 tattaaagct ttacaaacaa aattcggctc aattctctct attgcacctt ttgacactaa
    29281 tttttttata acggtatacg tagtgtttct attccatcct gtttcttctt ttaaaatttt
    29341 tactaactct ccagccttgc tttctcctct ctcccataga acttccatta ctttaagttc
    29401 tgaatcaaat aattttatct ccatataaaa tcgctcctca aatatagtta tcacaatagt
    29461 cattactata ataaaaaact atcatagtag tctatactat gtcaatcatt tattttttaa
    29521 taataaaaac tgtcttttta aaaaattctt ataaaagaca gttttatcaa tgttatactt
    29581 taatctttaa ttaaagccat attttattta aatatataac tatatatctt agtacatagt
    29641 ataagatttt tctttatcta atagtatatc ctctacatct gggttttctt ttactaattg
    29701 tctataaaaa ttacaattag taacacctac atatggaatt agccatagta gacctattcc
    29761 aagagtagct attgaaagta tataccatcc tataaaacta aagtttagta caaataattt
    29821 aagtacattt cctttcatca tatctaaact agcacccatt gatttaaata cacccatatt
    29881 atccttgtct tcacaaatta agaaagtagc ttgagaaaca tataatagca atatataaac
    29941 cggtaacata agaacaagta ttataagaac tagagttatt ccagtagaaa taacagtccc
    30001 tattccaaca ttatcacttg ataaatattc aattgctcca ctagtaagta aaactccaaa
    30061 tgataaaaac gctcctataa ttgtgattat aaaagaataa atataaacaa taattgattc
    30121 aaataaataa aaaccaaaac ttcttaaata aattctccca cttacaaaga tatctcctat
    30181 cttgactttt tcatctttag taattttcaa gaacatacat gtaaatcctg ctgaaacgca
    30241 aaaagctatt acagccacta caatagtagt caatggttca aaaggtaatc ctacaattga
    30301 tattaatact atcaatgcaa tatatactgc catagaaatt gcacatatcc cccagtttcc
    30361 agataactga gctttagata ctcgttttaa ttcttgcctt gataccataa aaaacacccc
    30421 tttcatttta taaaaaaact tttaaaaata taaataatct tttaacgtat aatattaata
    30481 tatcatattt tcgactatat aagatacaat tattcaccat gttttatcaa gatataccat
    30541 aattgtatta ctagttttat atagtcaaca ttaccaaata catcaaataa atttgattaa
    30601 ttattcaaca agtaataaaa taatttctat taattatact ttatttagta aa
//
LOCUS       DAEPKC010000042        30430 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.042, whole genome shotgun sequence.
ACCESSION   DAEPKC010000042 DAEPKC010000000
VERSION     DAEPKC010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 30430)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30430)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30430
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.042"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            94..849
                     /locus_tag="KR294_001931"
     CDS             94..849
                     /locus_tag="KR294_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003399531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH0240011.1"
                     /translation="MLQIKNLSKSFPNPYGEPNTIFENLSIDIEDGEFVSIIGSNGTG
                     KSTLLNIISGLIKESSGQITLDSTTITNLAEYKRTQIVSRVFQDPSLGTCPSMTVREN
                     LSLALNKGKLLNLKKCLRHKTNDLEHLLEGISLDLKKYLDIKVQYLSGGQRQSLSLIM
                     SSLASPKVLLLDEHTAALDPKTSNEVIELTDKIVREKNITTLMVTHNLKHALQYGDRL
                     IMLHKGEVVLDVKDKEKKDLTVEEILEKFEYAV"
     gene            946..1983
                     /locus_tag="KR294_001932"
     CDS             946..1983
                     /locus_tag="KR294_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBH0240012.1"
                     /translation="MIKSKKILSLIIAGVLGVSMLTGCSQNDGSNASNENKETDSKKQ
                     KNIGITQLVEHPSLDKAKKGFIKALEDKGYKDGDNIKIDFQNAQNDMPTTQSIASKFV
                     SDKKDLIYAISTPSAQAAYNATKDIPIIMTAVTDPVEAGLVKSLEKPGGNVSGTSDYL
                     SIDKTLELVKTLTPKAKKIGVIYNTSEVNSKIQVDSLHDYAKKNNYEVVEKGISSSSE
                     VNQAISSLVGKIDVLYVPTDNLIVSSMPIVSKVANENKIPIIASEEGSVSSGALACCG
                     IDYEKLGYKAGELAIEVLEGKSVGDIPVTTLDETEIIINEDTLKALDMQKLSADNIKY
                     IKSDENAKSTK"
     gene            2792..3694
                     /locus_tag="KR294_001933"
     CDS             2792..3694
                     /locus_tag="KR294_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0240013.1"
                     /translation="MSGIISVMTQSLILSIMALGVYITYKILDFPDMSADGSYTMGAS
                     IVAFSLTNGISPVVATLMAILCGCTAGLVTGILHIKFKISNLLSGILVMGMLYSINLR
                     IMGKSNIPLFSFKHLFNGEISPIVLALAFVFICKVLLDLFLKTGLGYTLKGVGDNSQM
                     IKSLGINIGSIKILGLMISNGLIALSGSLMAQFLGFSDVNMGIGTLVLGIASIIIGIT
                     LFKKFTFIKDTTAIIVGSFIYQFTIYFAMSLGMLSTDLKLITAIVIISFLATGNLNIS
                     LKKNKCKASTKNKSEKRGVVDVTN"
     gene            3681..4436
                     /locus_tag="KR294_001934"
     CDS             3681..4436
                     /locus_tag="KR294_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH0240014.1"
                     /translation="MLQIKNLSKSFPNPYGEPNTIFENLSIDIEDGEFVSIIGSNGTG
                     KSTLLNIISGLIKESSGQVLLNKHNLSNLAEHRRTQIVSRVFQDPSLGTCPSMTVREN
                     LSLALNKGKLLNLRKCLRYKRDFLENLLEGVSLDLKKYLDVQVKFLSGGQRQSLSLIM
                     SCLTNPSVLLLDEHTAALDPKTSNEVIELTNKIVREKNITTLMVTHNLKHALHYGDRL
                     IMLHKGEVVLDVKGKEKEQLTVEEILEKFEYAV"
     gene            4567..5589
                     /locus_tag="KR294_001935"
     CDS             4567..5589
                     /locus_tag="KR294_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBH0240015.1"
                     /translation="MINKKRLASLILAGALSISMLTGCSQGGDSGNSKQESNSKGKEV
                     KKIGITQLVEHPALDATRTGFVKALEKNGFKDGENIDIDFQNAQNDMPTTQSIASKFA
                     SDKKDLIFAISTPSAQAAFNATKDIPILITAVSDPVAAGLVKTLEKPGTNVSGTSDFV
                     SVDKGLELLKIFAPKAKTIGVMYNTSEVNSKVQVDALKEYASKNGFKVVEKGITTSNE
                     VNQGISSLVGKIDVLYVPTDNLVASSMPIVSKIATENKIPVIAAESGPVEKGALACQG
                     INYEKLGYKTGEMAVKILNGESVSDMPVATSDDTDIIVNEDILKALGMEKPSNENISY
                     VKTKQE"
     gene            complement(5753..6310)
                     /locus_tag="KR294_001936"
     CDS             complement(5753..6310)
                     /locus_tag="KR294_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HBH0240016.1"
                     /translation="MTEKEKMLSGKGYYANDELLVKEREYCKKLTRLFNNTLEDEYEK
                     REDILRQLFGSVGKQINVEQNIRCDYGYNIHVGENFFANYDCIFLDVCKIEIGDNVML
                     APNVQIYTAYHPIDAQLRNSGIEYGSPVKIGDNVWIGGGVIITPGITIGDNVVIGAGS
                     VVTKDIPPNTVAVGNPCRVIKKIEE"
     gene            complement(6316..7392)
                     /locus_tag="KR294_001937"
     CDS             complement(6316..7392)
                     /locus_tag="KR294_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate/molybdate ABC transporter ATP-binding
                     protein"
                     /protein_id="HBH0240017.1"
                     /translation="MSLYVDIEKDLSSFKLKVEIKQEKGTLGFLGESGSGKSMTLKCI
                     AGLEKPTRGKIVLNDRVLFDSEKKINLSTQDRKVGFLFQNYALFPHMTVSQNIELGLL
                     KLSKSEKKEIVARYLDILKLNGFEGRYPWQLSGGQQQRVALARALATSPDILLLDEPF
                     SALDHHLRSNMEKELMNMLKDYKGDILFVTHDIEEAYRVCDDIIVYNKGEGLPKRPKK
                     ELFESPKYLIEAKITGCKNISKLNRLDKNTIYATDWGCELTLNREIGDNIEYVGIREH
                     HIKVLDSNEDLNEKLCFELINIVENPFTYTIYVRKTDLSNECVPIQIELEKSKMRFKK
                     GDRIYLDFPQEYLFCFRYNYNKKE"
     gene            complement(7393..8076)
                     /gene="modB"
                     /locus_tag="KR294_001938"
     CDS             complement(7393..8076)
                     /gene="modB"
                     /locus_tag="KR294_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter permease subunit"
                     /protein_id="HBH0240018.1"
                     /translation="MGTDWSPLWISLKTSILSTIITFVIGIFVSYIMANYRGKWKGLI
                     DGLFTLPLILPPTVVGFFLLLLCGKNGFIGKFLLNFDRTLIFSWTATVISAVVVSFPM
                     MYRTSRSAFEQIDNNMLSAARTLGLNEWKVFFKIAVPLAWPGIIGGLVLSFARALGEF
                     GATLMIAGNIPGKTQTMPIAIFFAVEGGDMNKAMMWVMIIVAISIAMILLLNYWSEFQ
                     QKIIGKRCG"
     gene            complement(8225..9037)
                     /gene="modA"
                     /locus_tag="KR294_001939"
     CDS             complement(8225..9037)
                     /gene="modA"
                     /locus_tag="KR294_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBH0240019.1"
                     /translation="MKKILGILGLVACLTLGTVGCNSNEDKKDDGKQEKTTKSSDSVE
                     LNISAAASLKEAMAKIEEEYKKVDSNVKLTVNYGASGSLQQQIEQGAPCDLFISAGQK
                     QMKALDEEKLLVSDTMKDLVKNDLVLISSADSSVSGMEDLTTDKVKKIAVGEAESVPA
                     GKYADEVLTNLNLKDKLKDKLVFAKDVKEVLAWVQSGNADVGFVYFSDTVNNDKIKVV
                     EKTDEKTHSPITYPVSVIKASKNVDAAKKFEEFLLSESGQKIFEEFGYKKVE"
     gene            9230..10159
                     /locus_tag="KR294_001940"
     CDS             9230..10159
                     /locus_tag="KR294_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0240020.1"
                     /translation="MDSLSSLTPVEVAELLKITKNTVYELIKRGELPSYKVGKKIRVD
                     TKDVEEYINSQKTGKVKDTHFNNKNIDINNNFKIIISGQDVILDILARSVEKKLDGIS
                     TFRSYIGSYNALYELYNGRVSIASSHLWDFETDEYNSTFVKKLLPGIPCVLINLAYRM
                     QGFYVAKGNPKEITTWEDLTKPSITIVNREKGSGTRVLLDGKLRLLNFNGKHIKGYDN
                     EELSHLGVASTVSRGIADVGLGNEKAALQVNNIDFIPLHKERYDLVIKKEDLQNPVYQ
                     TIINIINSPEFKAELQGLGGYDLTDTGKTIAKV"
     gene            complement(10320..10769)
                     /locus_tag="KR294_001941"
     CDS             complement(10320..10769)
                     /locus_tag="KR294_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240021.1"
                     /translation="MKNKNNKDKNMLNIKVLRVLGVLLILFDYTGDTLNFYNFFAKPL
                     VSGNLYKTTGTDCIVFLLFIVECVYLVGRYILKVKINWSEIIENEKGNFINNLLVEKI
                     QEESNIVYNLLNSYVLPNIYKKARGLMFKTYHMLIYIKEKYYYVNIY"
     gene            complement(10972..11952)
                     /locus_tag="KR294_001942"
     CDS             complement(10972..11952)
                     /locus_tag="KR294_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBH0240022.1"
                     /translation="MKNSFKNCISLRNKFIIISIVFLLILLIVSYIFGKLVYNSSVGL
                     EQLIKNEDIVKIFSERKDKPLEKLKNYKTSELMIQSSNNYKLESLFITSNIKTRDTMI
                     LVHGIGSSYYEMLKVAYRYLDKGYNVLVYNQRNTGNSGGDNYTFGLYERYDLDSLVKF
                     VKNKFPEGRLGVHGFSMGAGTAAMHSEINSKDDKVDFYILDSPYSEMKDAIRMGVLEK
                     RIPDILINYVVTCGDLYNKFKSGFWYSDVKPYESVEKSNVPILFIHGTKDTVCNYQNS
                     KKMYDLVKHDKKDLWLIEGIGHVDGFEHDSTVYFNKIFKFIDSNVLSDKS"
     gene            complement(12157..13017)
                     /locus_tag="KR294_001943"
     CDS             complement(12157..13017)
                     /locus_tag="KR294_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-ADP-ribose hydrolase"
                     /protein_id="HBH0240023.1"
                     /translation="MAMKWRDYADDVNLFEDFDKTIKPLTDEQRRKNINTLIAYFSKE
                     VPSKIYNLSNDEIKPRDILRGLLNVYPPKEIAPEILNMLHNLLLIECEERELVDVNDI
                     EEVEEGIAIWRGNITNLRADAIVNAANNKLLGCLQPLHLCVDNEIHSCAGPRLREDCD
                     KIIKKQGHLEYTGDAKITRGYCLPAKFVVHTVGPIVSGGQPSKEQEKQLLHCYKSCLN
                     TIKEIDEIKNIVFCGISTGVFGYPKKEAANLAVSRVRLWLKENPEKNLKVVFNVFTEE
                     EEEKYRRIFK"
     gene            complement(13334..14662)
                     /locus_tag="KR294_001944"
     CDS             complement(13334..14662)
                     /locus_tag="KR294_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010963854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HBH0240024.1"
                     /translation="MEKFSVVIAGGGSTYTPEIILMLLDNLDRLPLRAIKLYDNDEER
                     QNKVAKACEILIKEKDPNIEYLATTCPKEAYTDVDFCLAHIRVGKLEMRELDEKIPLK
                     HGVVGQETCGPGGIAYGMRSIEGVLENIDYMEKYSPNCWMLNYSNPASIIAEAVRRLR
                     PNSRVINICDMPIGMEHNIARIAGLKSRKHMDIRYFGLNHFGWYTSIKDKKGNELLPK
                     LVEHIKEYGFINGEEGMKNDKKDSWFETNLFTKEIVKTDLTTIPSSYLKYYLFPDYVV
                     NHSDVNYTRANEVIDGREKEVFGSCALIEKQGHSKGSGLKIGIHAEFIVDLATALAFN
                     TQERMLLIVQNNGAIENIQDDAMVEIPCIVGKDGYEPLSIGKIPTFQKGLIEQQLAVE
                     KLVVDAWIEKSYNKLWQALMLSKTVPSATVAKELLDDLIEANKNYWPKLN"
     gene            complement(14810..15139)
                     /locus_tag="KR294_001945"
     CDS             complement(14810..15139)
                     /locus_tag="KR294_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBH0240025.1"
                     /translation="MVPEMEEKVFSIISEAGDAKSDVMMSLKEIKKGDYNKAKHLLNS
                     ASEKIQTASKHHLELLSNAMNSEDSGTDFLVVHSEDHYSNALFAHSLVSELVDIFEMM
                     DPRINKN"
     gene            complement(15163..16452)
                     /locus_tag="KR294_001946"
     CDS             complement(15163..16452)
                     /locus_tag="KR294_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH0240026.1"
                     /translation="MEALQNNLRRFLLPIAQKIEKQRHLQAIKEGMISITPIIIVGSL
                     SMLFMALNNMLPEGSAKTLLSENMDTLLIPNKFTMSLLSIYSAFFIAQALAKKYNLNH
                     VEIGMTAVVAQLVVCGQVVDGVLDTSYLDAQGLFVSILVALLVVDITKFMNDKNLVIR
                     FPKEVPSVVNKSFRNLTPMIVCIMLFTAIAAITKNVSGQPLPAIIMNFLAPAISSVDN
                     VFAVTIILFITQLLWFFGLHGAAITSSIWMPIAATYMAENATLIAAGGDPKYVFTIGF
                     YYGFLQVTGSGITLGLVYLMSRSKCKSFNSMGKVVILPSLFGINEPVIFGTPIVMNLY
                     MFVPFVFGPVLVGALNFMALKVGLVGLPIAEPPGFLPPGVAAFLMTLDWKAIVLVFAS
                     IILMTLIYYPFFKIMEKEELNKNAELATTLDDDSFDF"
     gene            complement(16468..16794)
                     /locus_tag="KR294_001947"
     CDS             complement(16468..16794)
                     /locus_tag="KR294_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH0240027.1"
                     /translation="MNILLVCANGASTGVLVEKMKSFCSEHEKLKTKTINIEATSFEN
                     LKSYIEANDTDVVLVAPQIRFKEDDVVEACKNYKIAVGLIDTKHYGRMDAPSVMKSAI
                     ELYKNR"
     gene            complement(16929..17558)
                     /locus_tag="KR294_001948"
     CDS             complement(16929..17558)
                     /locus_tag="KR294_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240028.1"
                     /translation="MQDKILRDKKANDPWARMTTRNGFSADEIISSFQKAIRRNMVEE
                     ACEFAYELYISSPELEDKLWRRILTISVEDIGMGDPSAVIIINNLNQVRKEYSYADGD
                     RPLFFIHAIRYLCACEKDRSSDLLKNIIIKGFAMGKVPEVMDVALDKHTYRGLEMGRD
                     SFHFLNEASIVIPEKEVDNDYKERYLKILEKYKQEEVIDTAFKFNHWQY"
     gene            complement(17774..20431)
                     /locus_tag="KR294_001949"
     CDS             complement(17774..20431)
                     /locus_tag="KR294_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH0240029.1"
                     /translation="MIYKKDKVMKVLESSYRENEKGITANQLSEKTGIARNNISTYLN
                     QLFNEGMVTKIKGRPVYYIPANLNLNKNELLDTQSELLGIKKGTKVENKIKKDSFETL
                     IGKEHSLRPIIEKCKVAMLYPTNGLHTIIYGETGVGKSMIARYMYDYSIDSGIRKNKA
                     PFVTFNCADYANNAQLLMGHIFGVEQGAYTGAESSRKGLLEIANGGILFLDEIHRLPA
                     EGQEMLFTFIDKGTFKRLGDATKERESKVLIICATTENPTSTLLDTFNRRIPMKIEIP
                     SLRDRTMIERMELVKNFFKEESKSISISIKVHKEIIKSLLLYDCKNNVGQLQNDIKLA
                     VANGYLRYKRDNKEPVYIEKKYFDKSINEVSDDYREKSIKADEVITHGIEYFVFTSLG
                     EEEVINYNDINIINAVNTNLNKSVEMNIADASLFNNVKFKSMCESIRQIIKEDEEIDI
                     SESIFKSMAIYIKSVLDKSSSTNNIDLNQIRRNNRSEFKTALKIVGIIENEFDLFLSI
                     ETVAYITLFIVQAKQDEQNKIVNNINIIVAMHGETTASSMVKAVGDIIGKCSAISFDM
                     KLDKSYDEVIVDFKNLINNIDNKDVLLFTDMGSLNSFDEIIKKEKKCGVRVIPMVTTL
                     TVLEAVQKANMGLPLNDVYNSITNTRKHYFGTNEIQNKENLSKTIIIASHVSEGVDNK
                     TRKILEEKMSRYLDGIDIISVPYKTEKDLSLNITKLKESSNIVAVINEQRINIRGIDY
                     ISKKDIDKDENINKLKNIIKISIGYDDVVEGLKTSLKSSNYNRIFKDIKYVSDELFLV
                     FNIEKKYDKVIGLMMHLAFMVDGLIGNTREIEKLDKEKTLDYHKSLSKIKDIVSQLDK
                     KYNIEINEKECYQILLILEYAEIIEKDYQ"
     gene            complement(20790..21734)
                     /locus_tag="KR294_001950"
     CDS             complement(20790..21734)
                     /locus_tag="KR294_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009527644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0240030.1"
                     /translation="MNREKILEIKNLKQYFHLDKSTTVKAVDDISFDIYKGEIFGLVG
                     ESGSGKSTTGKTIIRLHESTGGEVIYKGNCISDKKTYKFIKKDVNKSMQIIFQDSTSS
                     LNPRMTIADIISEPLKIQGICKNKTDRMNKVYEMLKLVGLDRSYANKYPSDFSGGQRQ
                     RIGIARALSVDPEFIIADEPIASLDVSIQAQIVNLFKKLQQEKNLTCLFIAHDLSMVR
                     HISDRIGVMYNGKLVELADSNELYNNPIHPYTKSLLSAIPVPDPRYAKSRNRIEYNSN
                     GYDCSNEKSLSWIEVSDGHFVYSSKSEINKYQQNLKVV"
     gene            complement(21727..22752)
                     /locus_tag="KR294_001951"
     CDS             complement(21727..22752)
                     /locus_tag="KR294_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0240031.1"
                     /translation="MEHLLEVNNLSVSFKVEEGEVQAVRNVSFNLKKGETLAIVGESG
                     CGKSVLCKSLMRILPYNGYIKNGEVLLKSSDLVKKSEKEMEDIRGKNISMIFQDPMTS
                     LNPTISIGKQIAEAVIIHQGISKSEAKKRAIELIELVGIDNPEKRFKQFPHHFSGGMR
                     QRIVIAIALACNPDVLIADEPTTALDVTIQAQIIDLIKDLQHKIGLSIIFITHDLGVV
                     ATIADRIAVMYAGKIVEIGTVEDIFYDPRHPYTWGLLGSLPTLDSQDDYLYNIPGMPP
                     NLLNPPKGDAFAIRNKNALKIDYEKEPPMFKINDTHSAATWLLHPDAPEVDVPVRVNC
                     GRVISNE"
     gene            complement(22827..24395)
                     /locus_tag="KR294_001952"
     CDS             complement(22827..24395)
                     /locus_tag="KR294_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBH0240032.1"
                     /translation="MKLKKLKVLSLVMILSLMAGCSSGGDKDKKADTPKDGKVLVYGS
                     NDYTSINPALYEHGEINSLIFNGLTAHDENNKVVPCLAKDWKFDEATNTYTFNLRDDV
                     KWHDGEKFTANDVKFTIETIMNPDNASEIASNYEDITKIDVVNDNTIKITLKAPNTAM
                     LDYLTVGVLPKHALEGKDIATDEFNQKPIGTGPFKLEKWDKGQSITLVKNSDYFVKEP
                     GLDKVVFKIVPDDKAKAMQLKSGELDLAQITPKDMSNFEKDEKNFKVNIMKTADYRGI
                     LYNFNSKFFKDKKAKGLPNALSYAIDRKAIVDSVLLGHGVPAYSPLQMGPYNNPDIEK
                     FEYNPEKAKQEIEKLGWKLGSDGIYEKEGTKLAFEITAGESDQVRVDMAKICAQQLKE
                     IGVDAKAVVVTETDWANQDAHLIGWGSPFDPDDHTYKVFGTDKGANYSAYSNPTIDKI
                     LQKARETEDKDEKLKLYKQFQVEMTKDMPYTFIAYIDAIYVGKPNIKGLTPDTVLGHH
                     GVGVFWNIADWTIE"
     gene            complement(24508..25419)
                     /locus_tag="KR294_001953"
     CDS             complement(24508..25419)
                     /locus_tag="KR294_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0240033.1"
                     /translation="MKPQYSDFEIVGENYILVAEDEHIETKKTLSKKIKELPYISIII
                     LSIIVIGSVFSSFIMTHEPTYMDLASSNLAPNKTFLFGTDSMGRDIYSMIWYGGKISL
                     FIGLFSTVISTVIGIVYGSISGSASELVDDAMMRFTEIILSIPSILIIIFVQAILGNS
                     NPVSMSIVIGITSWMNISKIVRTEVRQIKNSEYILAAKSMGGGFFYVLKQHLLPNFVA
                     SIMFMVVTNIGAAIGTESTLSFLGIGLPIEIVSWGSMLSLSEEALLSNRWWIILIPGI
                     FLVTTLVCITNIGNYIRKNNNKKSSNL"
     gene            complement(25403..26389)
                     /locus_tag="KR294_001954"
     CDS             complement(25403..26389)
                     /locus_tag="KR294_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0240034.1"
                     /translation="MLKDILKKLLQFILVMFLLSFIVFYMARLAPGDPLISYYGDGVE
                     RMSTQEKENAMKKLGLDEPIYSQYIKWISNASKGEFGISFKYKQNVTSVINDVYINTI
                     ILGGSGYILTFVLALLLGIFCTLHEDKLIDRIICKLGTITNCIPSFWVALVLILIFSI
                     NLSILPSSGAYSMGEESSILSRISHLILPLTVLILSHLWYYTYMIRNKLLEEIREDYV
                     LLCKAKGLNNRTIVFKHCLRNIMPSYISIMAISIPHILGGTYVVEKVFSYPGLGTLCF
                     ESAKYHDYNMLLVLCLITGALVVFGNMLAQIINNKIDPRMKYDRGDTNEATI"
     gene            26749..27150
                     /locus_tag="KR294_001955"
     CDS             26749..27150
                     /locus_tag="KR294_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBH0240035.1"
                     /translation="MLLKELYSKTMYTVEENFKENGLTHQQIIVIKLIAHNQELTISQ
                     LCDEMSLAKGTVSGIISRLEQIGYIEKFKKSNDKRNTYVKFTTTGFEFATNFKIKMQE
                     SFDDIFKNCDENELSDLVKNLRNILAKVKER"
     gene            27153..27551
                     /locus_tag="KR294_001956"
     CDS             27153..27551
                     /locus_tag="KR294_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03987 family protein"
                     /protein_id="HBH0240036.1"
                     /translation="MNYKLILAIVFITSALIFYTIGVFGERKAKILKKKHVIIFWLGF
                     IFDTLGTFTMSNIANSHTFEVKSALSQNLHSITGLLAIVLMLFHASWATFVLYKDDEE
                     KKKFFHKFSIVVWTIWLVPYFIGMFIGMAG"
     gene            complement(28001..28225)
                     /locus_tag="KR294_001957"
     CDS             complement(28001..28225)
                     /locus_tag="KR294_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NifU family protein"
                     /protein_id="HBH0240037.1"
                     /translation="MREKVEKVLEEKIKPVLQRDGGDVELIDVNENGVVLVRLQGACS
                     GCPGATMTIKAIIENVLVSEVPGVTQVLGV"
     gene            complement(28260..29627)
                     /locus_tag="KR294_001958"
     CDS             complement(28260..29627)
                     /locus_tag="KR294_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH0240038.1"
                     /translation="MKEYIINNVEEIREELIDLSKKIWENPELAFEEKYASSIQKEYL
                     KSKGFKIEEVENLPTGFIASFGEGKPVIGILGEYDALPELSQCVSAERKPLVEGKAGH
                     GCGHNLLGVAGVGAVVSIKKLIEENKFNGTIKYFGCPAEEEGGGKTAMCINGCFDDVD
                     CAFTWHPFDINAPWRGGSLANLSVKFKFKGITAHAAQAPHNGRSALDAVEIMNVGANY
                     LREHVIDSIRMHYVITNGGGRPNVVPGFAESWYFIRGKKAKDAEHVLDRLIKVAQGAA
                     MMTETEMEYKVTDGIYDYIPNQCLTDLVYDNMVFVGCPKNTPEEEEFAKKLCDTLTRE
                     ERLGVATSLQNDKSIVESYIHKEIVDGDKDKGLAGSTDVGDVSYVIPVAQFAMAAWPV
                     GIASHTWQSCSSAGSNIGFSAMINSAKVLACSAYDVFMDTKIIDEAKIEFDKSLDGQK
                     FKPLV"
     gene            complement(29711..>30430)
                     /locus_tag="KR294_001959"
     CDS             complement(29711..>30430)
                     /locus_tag="KR294_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240039.1"
                     /translation="DKVIDSEESNIIELIEVDDSFNTEVDSNLDYNDFEEINREIRIN
                     KKITLLLMEAIEVLIKRLSIEDEDVIRYIKKYEKIFIESVLSSIKSNTFKSMVTVSKN
                     KKEHLEDYIVDDESKLDDESFREIFNEILDSTSIIEKIRIIKENINAKKDFIDILESE
                     CLFGEEYLMLFASLSELELAILGSVVFYEDIRMREINILEFMLNEKTETTLWKIEYIK
                     FMKRQSEDKIYSIEEHMNKIN"
BASE COUNT        10039 a         5154 c         3522 g        11715 t
ORIGIN      
        1 ctttcctagc tactggtaac ttaaatattt cactaaaaaa aaacaaatgc aaagctagta
       61 ccaaaaataa atcagaaaaa agaggtgttg tagatgttac aaattaaaaa tctttcaaag
      121 agtttcccta atccatatgg tgaacctaat actatctttg aaaatttatc aatcgatata
      181 gaagatggtg aatttgtaag tatcataggt agtaatggaa ctggtaaatc tactttatta
      241 aatataatat ctgggcttat aaaagaatct tctggtcaaa ttactttaga tagtactact
      301 ataacaaatt tagctgagta taaaagaact caaatagtaa gtagagtttt tcaagaccca
      361 agccttggaa cttgtccttc tatgacggtt agagaaaatt tatctctagc acttaataaa
      421 gggaaattat tgaacttaaa aaaatgtctt cgtcataaaa cgaatgactt ggaacactta
      481 cttgaaggaa tttctttgga tttaaaaaaa tatttagata ttaaagtaca atatctttca
      541 gggggtcaaa gacaatcact atcactaatt atgtctagct tagcaagtcc taaggtctta
      601 ttactagacg aacatacagc agcacttgac ccaaaaacat caaatgaagt aatagagtta
      661 acagataaaa tcgtaagaga gaaaaatata actacactta tggttactca caacttgaaa
      721 cacgctcttc aatatggaga taggttgata atgcttcata agggtgaagt tgtattagat
      781 gtaaaagata aagaaaaaaa agatttaaca gttgaagaaa tcttagaaaa atttgaatat
      841 gcagtataag aaattaaaat cttagtttta atcagaaata tttataatct atcatatgaa
      901 tatatgaaca aatataatta ttaaatttta agggaggaaa ataaaatgat aaaaagtaaa
      961 aaaatattaa gtttaattat agcaggagta cttggtgtat caatgcttac tggatgttct
     1021 caaaatgatg gctccaatgc ttcaaatgaa aataaagaaa cagatagcaa aaaacaaaaa
     1081 aatataggta ttactcaatt agtggaacat ccatctctgg ataaagcaaa gaaaggattc
     1141 atcaaagcac ttgaagataa aggctataaa gatggagata atataaaaat agatttccaa
     1201 aatgcacaaa atgatatgcc tactacacaa agtattgcta gtaagtttgt atccgacaaa
     1261 aaagatttga tatatgctat atctactcca tctgcacaag cagcttataa tgctactaaa
     1321 gatattccaa taataatgac tgctgttaca gaccctgtag aagctggact tgttaaatct
     1381 cttgaaaaac caggtggaaa tgtttctggt acatctgatt atctttcaat tgataaaaca
     1441 ttagaattgg ttaaaacatt gactccaaaa gcaaagaaaa taggggttat atacaatact
     1501 agtgaagtta attcaaaaat ccaagttgat tctctacatg attatgctaa gaaaaataat
     1561 tatgaagtag ttgaaaaagg aatcagctct tcaagtgaag ttaaccaagc tatttctagt
     1621 ttagttggta aaatagatgt tttatatgtc cctactgaca atttaatagt ttcttctatg
     1681 ccaatagttt ctaaagttgc taatgaaaac aagattccta taatagcctc tgaagaaggt
     1741 tctgtatctt ctggtgcttt agcttgttgt ggaatagatt atgaaaaact aggttataag
     1801 gctggagaac ttgctattga agtattagaa ggaaaatctg ttggcgatat accagttact
     1861 acattagatg aaactgaaat aataattaac gaagatacac taaaagcact tgacatgcaa
     1921 aagttatcag cagataatat aaagtatata aagtcagatg aaaatgcaaa atctacaaaa
     1981 taaaacttat taatttcaaa aaataggtaa tatgaagtag gtaatatgaa aactttatat
     2041 aataagtact cttatccacc ctaacccttt gaaaattgtg cttattgtag caatttgaat
     2101 attgcatata aagttattca ttttccataa aagtcgtcta tattgacgac tgattatgaa
     2161 agttatataa ctttctaatc actacttgag ctgtccaaaa gaattttaat attctccaga
     2221 cagctttttt ttatgatatt tgattgatat acatgtctag ttattccata tttagtaaat
     2281 attttgataa aatttccaca ttcacttata acttaggata acgttttttt caaacaatac
     2341 attaatttaa aagtattctg agtatacatt atttagtatt ttaattaaat ttagcagttg
     2401 acttttatta ttgtataatt tataatttat aacaagtcga gaatacatat aattttctga
     2461 ctaattaaaa tattaaaagg gagagataat tatgaatact ttattaaaca atagaaaata
     2521 ttattattat tatagccact atttttaggg tttgtaccta cgttttaaca tagatacaga
     2581 ccccttaaga ctactaaaat tttgggattg tatctatgtt ggctatattg tttataaagt
     2641 tttcatttaa ctatataaga gccacataga ttaaactatg tggcttattc gtgtttttac
     2701 cacatagttt tgtacactat gtggtttttt tatacacaaa attagcaaat aattaaaatt
     2761 ataaaaatat tttcaaagga gtgttttatt tatgtcaggt attatatctg taatgacgca
     2821 aagtttaatt ttatcgatta tggcactggg ggtttatata acttacaaaa tcttagattt
     2881 tccagatatg tctgctgatg gtagctacac aatgggtgct tctattgtag cattttctct
     2941 tactaatggt atttctcctg tagtagcaac tttaatggct atcttatgtg gttgtactgc
     3001 tggtcttgtt acagggattc ttcacattaa gtttaagata tctaacttac tttctggtat
     3061 tttagttatg ggaatgctat actctatcaa tttaagaata atgggaaaat caaatattcc
     3121 tctatttagc tttaaacact tattcaatgg ggaaatatct cctatagttt tagccttagc
     3181 ttttgtattc atctgtaaag tccttttaga tttattccta aaaacaggtc ttggatacac
     3241 tttaaaaggt gttggtgata actctcaaat gattaaatcc ctaggtataa atatcggttc
     3301 tataaaaata ctaggactta tgatttcaaa cggacttata gctttatctg gtagtcttat
     3361 ggctcagttc ttgggattct cagatgtaaa tatgggtata ggaactttag ttcttggaat
     3421 tgcctctatc ataattggta ttacactatt taagaaattt acttttatca aagatactac
     3481 tgcaataatt gttggctctt ttatatacca attcactata tactttgcaa tgagtttagg
     3541 aatgttatca actgacttaa aactaataac tgccatagtt ataatatctt tcctagctac
     3601 tggtaactta aatatttcac taaaaaaaaa caaatgcaaa gctagtacca aaaataaatc
     3661 agaaaaaaga ggtgttgtag atgttacaaa ttaaaaatct ttcaaagagc ttccctaatc
     3721 catatggtga acctaatact atctttgaaa atttatcaat cgatatagaa gatggtgaat
     3781 ttgtaagtat cataggtagt aatggaactg gtaaatctac tttattaaat ataatatccg
     3841 ggcttataaa agaatcttct ggtcaagtat tattaaataa acataacttg tctaatttag
     3901 ctgaacacag aagaactcaa atagtaagta gagtttttca agacccaagt cttggaactt
     3961 gcccttctat gactgttaga gaaaacttgt ctttagctct taacaaagga aaactattaa
     4021 atctaagaaa atgtcttcgt tacaaaagag atttcttaga aaatttattg gaaggtgtat
     4081 ctcttgattt aaaaaaatac cttgatgttc aagtaaaatt tttatcagga ggtcaaagac
     4141 aatcattatc actaattatg tcgtgcttaa caaatccatc agttttatta cttgatgaac
     4201 atacagcagc acttgaccca aaaacatcaa atgaagtaat tgaattgact aataagattg
     4261 taagggaaaa aaatataact acacttatgg ttactcacaa cttaaaacac gctcttcatt
     4321 atggtgatag attgataatg cttcataagg gtgaagttgt attagatgta aaaggtaaag
     4381 aaaaagaaca attaacagtt gaagaaatct tagaaaaatt tgaatatgca gtttaaaata
     4441 atatatctat tgtattaaac tcggctttaa aataaagtta aaattacaat aattatggtt
     4501 actttgtaat aattcatatg aatatatgaa catatataat aataaatttt tgagggggat
     4561 ataaaaatga ttaataaaaa aagattggca agtttgattt tagctggtgc tcttagtata
     4621 tctatgctta cagggtgttc acaaggagga gactctggta attcaaaaca agaaagtaat
     4681 tctaaaggta aagaagttaa aaaaattggt ataactcaac tggttgaaca tccagcatta
     4741 gatgccacta ggacaggttt tgtaaaagca ttagaaaaga acggatttaa agatggagaa
     4801 aatattgata tagacttcca aaatgctcaa aatgacatgc ctactacaca aagtattgcg
     4861 agtaaatttg catctgataa gaaggactta atatttgcta tatctactcc atcagctcag
     4921 gcagcattta atgctactaa agatatacct atacttatta ctgctgtgag tgaccctgtt
     4981 gctgctggat tagttaaaac tcttgaaaag ccaggcacaa atgtatctgg aacatcagat
     5041 tttgtttctg tagacaaagg tttagaactt cttaaaatat ttgctcctaa ggcaaaaact
     5101 ataggagtta tgtacaatac tagtgaagta aattccaaag tccaagttga tgctttaaaa
     5161 gaatatgcat ctaaaaatgg atttaaagtt gttgaaaaag gtataactac ttcaaatgaa
     5221 gttaaccaag gtatttctag tttagttggc aaaatagacg tattatatgt tcctacagat
     5281 aacttagtgg cttcttctat gcctatagtc tctaaaatag ctactgagaa taaaatacct
     5341 gttatagcag ctgaatctgg gccagttgaa aaaggtgctc ttgcttgtca aggtatcaac
     5401 tacgaaaaac taggttacaa aacaggtgaa atggcagtta aaattttaaa tggtgaatca
     5461 gtatctgata tgcctgtggc tacatcagat gatacagata tcattgttaa tgaagatata
     5521 ttaaaagctt taggtatgga aaaaccttct aatgaaaata tttcttatgt aaagactaaa
     5581 caagaataga aagatatttt ctatatacga ttaatatgcc tgtttctata aattaattta
     5641 tagaaacagg catatatttt tattttaatg tattatctat ttaaagatta tatgtaaatg
     5701 ctcttaattt gtttgtataa attttacttg tataaacttt atacaatcat atttattctt
     5761 ctattttctt tattactcta catggatttc caacagctac agtatttggt ggtatatctt
     5821 ttgtgactac acttcctgca cctattacta cattatcacc tatagtaatt cctggtgtta
     5881 tgattactcc cccacctatc catacattat cacctatttt tacaggagaa ccatactcta
     5941 tacctgaatt tctaagttgt gcatcaattg gatgataggc tgtatagatt tgaacgtttg
     6001 gagctaacat tacattgtca cctatttcaa ttttacatac atctaaaaaa atacaatcat
     6061 aatttgcaaa gaaattttcg cctacatgta tgttatatcc ataatcacac ctaatatttt
     6121 gttctacatt tatttgcttg ccaactgaac caaatagttg tcttaaaata tcttctcttt
     6181 tttcatattc atcctctaaa gtattattaa acaatctagt taatttttta caatactctc
     6241 tttcttttac taacaattca tcatttgcat agtatccttt cccagacaac attttttctt
     6301 tttcagtcat atagtttact cctttttgtt ataattgtat ctaaagcaaa ataaatattc
     6361 ctgtggaaaa tctaaatata ttctgtcacc tttcttaaat ctcattttac ttttttccaa
     6421 ttctatttga ataggtacac attcgttaga taaatcagtt tttctaacat atatagtata
     6481 tgtaaaagga ttttctacaa tgttaatcaa ttcgaaacat aacttttcat ttaaatcttc
     6541 attagaatcc aagaccttaa tatgatgctc cctgattccc acatattcta tattatcacc
     6601 tatttctcta tttaatgtca actcgcatcc ccagtctgta gcataaatag tatttttatc
     6661 cagtctattt aatttggata tatttttaca ccctgttatc ttagcttcta taaggtactt
     6721 tggagattca aagagctctt ttttaggtct ctttggaaga ccttctcctt tgttgtacac
     6781 tataatatca tcacaaactc ggtaagcttc ttcaatatca tgagtaacaa atagtatatc
     6841 tcccttgtaa tcttttaaca tattcataag ttctttttcc atattgcttc ttaaatgatg
     6901 gtccaatgct gagaaaggtt catctaaaag taatatatct ggagatgttg ccaatgctct
     6961 agctagtgct accctttgtt gttgaccacc agataattgc caagggtatc tcccctcaaa
     7021 cccatttaat ttaagtatat ctaagtacct tgctactatt tccttttttt cactcttact
     7081 tagttttaaa agcccaagtt ctatattttg acttacagtc atatgtggaa acaaagcata
     7141 gttttgaaat aaaaatccta cctttctatc ttgtgttgat aaatttatct tcttttcaga
     7201 atcaaataga actctatcat ttaatacaat tttacctctt gttggtttct caagccctgc
     7261 tatacatttt aatgtcatac tttttccaga accagattct cccaaaaacc ccagagtacc
     7321 tttttcttgt ttaatttcta cctttagttt aaaagaggat aaatcttttt caatatccac
     7381 gtataagctc aactatccac acctctttcc tataattttc tgctgaaatt ccgaccaata
     7441 atttagtaat aaaatcattg ctatagatat tgctacaata atcataaccc acatcatagc
     7501 tttattcata tctccgcctt caacagcaaa aaatatagct attggcatag tttgagtttt
     7561 tccaggtata tttccagcta tcataagtgt agcaccaaat tctccaagag ctctggcaaa
     7621 cgacagcacc aatccaccaa ttattccagg ccatgctaat ggaactgcaa tcttaaaaaa
     7681 tactttccat tcattaagac ctaatgttct agcagctgac aacatattat tatcaatctg
     7741 ttcaaaagct gaccttgaag ttctatacat cataggaaaa gacaccacta ctgctgaaat
     7801 tacagttgct gtccaactaa atattaaagt cctatcgaaa tttaataaaa actttcctat
     7861 aaatccattc ttcccacata gtaataataa aaagaaacct acaactgttg gtggcaaaat
     7921 tagtggaagt gtaaatagtc catctataag acccttccac ttacctctat agttagccat
     7981 aatatatgac acaaatattc ctattacaaa agttattatt gttgacaaaa tagatgtctt
     8041 aagtgatatc cataagggtg accaatctgt tcccatcttt ccctccttaa ttttaaatgg
     8101 aaatagtgaa actaataact ctattaattt cactatttcc attttattat aatacacaat
     8161 tattttcaat tttcatttat ttatatataa tttatactta attacacata atttatttct
     8221 aagtttattc tactttttta tatccaaatt cttcaaaaat cttttgtcct gactcactta
     8281 ataaaaattc ttcaaatttc ttagcagcat ctacgttttt actagcttta attactgaaa
     8341 ctggatatgt aataggcgaa tgagtttttt cgtctgtttt ttcaactact tttatcttat
     8401 cattattgac agtatcactg aagtaaacga atccaacatc agcatttcct gattgcaccc
     8461 atgctaaaac ttcttttaca tcttttgcaa atactagctt atcttttaac ttatctttta
     8521 aatttaaatt agttaacacc tcatctgcat acttaccagc tggaacactt tcagcttcac
     8581 caacagcaat tttcttcact ttatctgtag tcaaatcttc catacctgat acactactgt
     8641 cagcagaaga aataagaact aaatcatttt ttactaaatc tttcatagta tcagaaacta
     8701 ataacttctc ttcatccaaa gctttcattt gtttttgacc tgctgaaata aataaatcac
     8761 aaggtgctcc ttgttctatt tgttgttgta atgagcctga tgctccatag ttaactgtaa
     8821 gttttacatt tgaatcaact tttttatatt cttcttcaat ctttgccatt gcttctttta
     8881 aacttgcagc agccgatata tttaactcta ctgaatcact acttttagtt gttttttctt
     8941 gttttccatc atcttttttg tcttcattac tattgcaccc aactgtcccc aaagttaaac
     9001 atgcaactaa tcctaatatt cccaatattt ttttcataac aatctccctt tttgtaaatt
     9061 tgatacacat tttaacatgt tttattatgt tttatcatgt tttgttatat atagtttaat
     9121 tatatataca tgataataaa ttttcaagta atttatttac actactttta aatattttgc
     9181 tacattttcc tttttttaat gttaaaataa ccttatatgg aggtggatta tggactcatt
     9241 atcatctttg acacctgtcg aggtagctga attattaaag ataacaaaaa atactgtata
     9301 tgaattaatc aaaagaggtg aacttccttc ttataaagta gggaaaaaaa taagagttga
     9361 tactaaagat gttgaagaat atatcaacag ccaaaaaact ggtaaagtaa aggatacaca
     9421 tttcaacaat aaaaatatag atataaataa taatttcaaa attattattt ctggtcaaga
     9481 tgtaatatta gacattttag ctaggtctgt tgaaaaaaaa ttggatggaa taagtacatt
     9541 tcgctcttat ataggtagtt ataatgcttt gtatgagtta tataatggca gagtttctat
     9601 agcatcatcc catctatggg atttcgaaac ggatgaatat aatagcactt ttgttaaaaa
     9661 gctattgcca ggaataccat gtgtacttat aaatctagct tatagaatgc aaggtttcta
     9721 tgttgctaaa ggaaatccta aagagataac aacctgggag gatttaacaa aaccaagtat
     9781 aaccattgta aatagggaaa aaggttctgg aactagggtt ttactagatg gtaaacttag
     9841 acttctaaac tttaatggta aacatataaa aggttatgat aatgaagaat tatcacatct
     9901 tggagttgca agtactgttt ctcgtggaat agcagatgtt ggtttgggaa atgaaaaagc
     9961 tgctttacaa gtaaataata tcgactttat tcctcttcac aaagagcgct atgatttagt
    10021 tattaaaaaa gaagacttac aaaatccagt ttaccaaact ataattaaca taataaactc
    10081 tcctgagttt aaagctgaac ttcaaggtct tggcggatat gatttaactg atactggaaa
    10141 aactatagca aaagtttaag attaaaatcg caatctattt tataagattt ataatttttc
    10201 acaaaattta taacttaaac acgaaataaa ttgcgatttt agtgtctcaa aaaatttatg
    10261 tctttcattt tatcatccaa tacaaaatat aatataatta attgtgcaat catattatat
    10321 taatatatat ttacataata gtatttttct ttaatgtaga ttaacatatg atatgtttta
    10381 aacatcaatc cccttgcttt cttatatata tttggcaaca catatgagtt taataaatta
    10441 tatacaatgt tgctttcttc ttgtattttt tcaaccaaca agttatttat aaaattacct
    10501 ttctcatttt caataatctc actccaattt atcttaactt ttaatatata tcttcccact
    10561 aggtatacac actctacaat aaataataaa aatacaatgc agtcagtacc tgttgtctta
    10621 tataaattac ccgatactaa tggctttgcg aagaaattat aaaaattcaa agtatcaccc
    10681 gtataatcaa aaagtattaa tagcactcct agaactctca atactttaat attcaacatg
    10741 tttttatctt tattattttt gtttttcata tatactacct ctcttttctt tagatttgat
    10801 tgtaatctaa tactaactct tttatttgag gtataaatga atttaattgg tagttatttt
    10861 catttttact agaaattaat tcacattact aaacaaaact tatatttaaa cataaaaata
    10921 gcctatctat cttttaataa atacaaaaat aaataagcta ctaatattca attaactttt
    10981 atcacttaaa acattactat ctataaattt aaatatttta ttgaagtata ctgtactatc
    11041 atgttcaaat ccatcaacat gaccaatacc ttctataagc cataggtctt ttttatcatg
    11101 tttaactaaa tcatacattt tcttgctatt ttgataatta caaacagtat cttttgttcc
    11161 atgtataaac agtatgggta cattagattt ctcaactgac tcatatggtt ttacatcact
    11221 gtaccaaaat ccagatttaa acttattata taaatctcca caagtcacca cataattgat
    11281 taatatatct ggtattcgtt tttctagtac tcccattcta attgcatctt tcatttcaga
    11341 ataaggagaa tccagtatat aaaaatcgac cttatcatct tttgaattta tctctgaatg
    11401 catagcagct gtccctgccc ccatggaaaa tccatgcaca cctaatctcc cttcaggaaa
    11461 tttatttttt acaaatttaa ctagactatc taaatcatac ctttcataaa gaccaaatgt
    11521 gtaattatct ccaccactat taccagtatt tctttgatta taaactaata cattataacc
    11581 tttatctaaa tatctatatg ctacctttaa catttcatag taactacttc caattccatg
    11641 aacaagtatc atagtatctc ttgtctttat atttgaagtt ataaaaagac tttcaagctt
    11701 gtaattatta gaactttgta tcattaattc agatgtcttg tagtttttta atttctccag
    11761 tggtttatct tttctctcag aaaatatttt tactatatct tcgtttttta ttaactgctc
    11821 taaaccaact gaactattat acactaattt tccaaatata taagatacaa ttaataggat
    11881 taatagaaac acaattgata taattataaa tttatttctt aaactaatac aatttttaaa
    11941 actatttttc atatttattt accatacaat tttcctatat tatattttct aagtaatagc
    12001 ataattgatt atactattct tataatttct attataccta cttatttatt aaaaatacaa
    12061 attatatttt attaattttt actacttgta aattattatc ttatacaatg aatttgtatt
    12121 atataataag tatttttagg attctgttac ataatattat ttaaatattc ttctatattt
    12181 ctcttcttct tcttcagtaa acacattaaa tacaactttt aaattttttt caggattttc
    12241 ttttagccat agtctaactc tacttacagc aagattagct gcctcttttt ttggataacc
    12301 aaatacacct gtagaaattc cacaaaaaac aatatttttt atttcatcaa tttcttttat
    12361 tgtatttaaa catgatttat aacaatgaag cagttgcttt tcttgctctt tacttggctg
    12421 accaccagat acaataggtc caacagtatg tactacaaat tttgcaggta aacaataacc
    12481 tctagttatc ttagcatctc cagtatattc taaatgccct tgttttttta ttattttgtc
    12541 acaatcttct ctaagtctag gacctgcgca tgaatgtatc tcattatcca cgcatagatg
    12601 taatggttgt aaacacccta ataacttgtt atttgcagca tttactattg catctgctct
    12661 taaattcgtt atattacctc tccatatggc aatcccttcc tctacttctt ctatatcatt
    12721 tacatctact aactctcttt cttcacattc aatcaacaat aaattatgta acatattaag
    12781 tatctctgga gcaatttctt ttggtggata tacattcaaa agtcctctaa gtatatctct
    12841 aggcttaatt tcatcatttg ataaattgta tattttagaa ggaacttctt ttgaaaaata
    12901 tgcaattaaa gtgtttatat tttttcttct ttgttcgtca gttagaggct tgatagtttt
    12961 atcaaaatcc tcaaataaat ttacatcatc agcataatct ctccacttca tagccatctc
    13021 tccattcttg tattttagac ttaaaaataa ttatgtattt atgtacatat ttatttattt
    13081 ctataaacac ctacataaat cctgttaaaa gtgtaaattt tttattatac aacttctctg
    13141 gttatttcta ttgattgata gtaaattatt gtacctaaat ttaatccaac taacaagtaa
    13201 ctaaacctac tttcctaact gcaaaataca ctatgtttgc cacttgtatc tcatttgtag
    13261 ataaataaag tccctacaaa tacattaact aggctatgta ctaaactgta ggaactttaa
    13321 aaatatatta ttcttaatta agttttggcc aataattttt atttgcttct attaaatcat
    13381 ctagtaattc ttttgcaact gttgcactag gaactgtctt agatagcata agtgcttgcc
    13441 acaatttatt ataagacttc tcaatccaag catcaactac taatttttca actgctaatt
    13501 gttgttctat taaacctttt tggaatgttg gtattttccc tattgataat ggttcatacc
    13561 cgtcttttcc aactatacat ggaatttcaa ccatagcatc atcttgtata ttttctatag
    13621 ctccattatt ttgaactatc aataacatac gctcctgtgt attaaaagct agagctgtag
    13681 ctaaatccac tataaactct gcatgtattc ctatcttaag cccactgccc ttagaatgtc
    13741 cttgcttttc tatcaatgca catgaaccaa aaacttcttt ttctcttcca tcaataactt
    13801 cattggcacg agtataattt acatcagaat gatttacaac ataatctgga aatagatagt
    13861 actttaagta actacttggt attgtagtta aatctgtttt tactatttct ttagtaaata
    13921 aattagtttc aaaccaacta tctttcttgt catttttcat tccttcttca ccatttataa
    13981 aaccatattc ttttatatgt tctactaatt ttggtaaaag ttcatttcct tttttatctt
    14041 taattgaagt ataccaacca aagtgattta atccaaagta tcttatatcc atatgtttac
    14101 gagatttgag tcctgcaatc cttgctatat tatgttccat acctattggc atatcacaaa
    14161 tatttattac cctagaatta ggtctcaacc ttctaacagc ttccgctatt attgatgctg
    14221 gattagaata atttaacatc caacaatttg gagaatactt ttccatataa tctatgtttt
    14281 caagaacacc ttctatagac ctcattccat aagctattcc acctggtcca caagtttctt
    14341 gaccaactac cccatgtttt agaggtatct tttcatctag ttctctcatt tcaagttttc
    14401 caactcttat atgagctaaa caaaaatcta catctgtata agcctcttta gggcatgttg
    14461 ttgctaaata ctctatatta gggtcctttt cctttattag tatttcacaa gctttagcta
    14521 ccttattttg tctttcttca tcattatcat ataatttgat tgctcttaat ggtaacctat
    14581 ctaagttatc tagcaacatt aatatgattt ctggggtata tgtacttcct cctccagcta
    14641 ttactactga aaatttttcc ataataatat ctccttttct atttaaaaat ttactgtatt
    14701 tataaataaa tttataaata ctagtacttt aaagtaaaag ggagttcatt tattaaatct
    14761 attgatttaa taaactatag ccaaacttca agcactattt acaagaaatt taattcttat
    14821 taattcttgg gtccatcatc tcaaatatat ctacaagttc agatactaaa gaatgagcaa
    14881 ataatgcatt tgaataatgg tcttcagagt gcacaactaa aaaatcagtc ccactatctt
    14941 cactattcat agcatttgat agtaattcta aatgatgctt tgatgctgtt tgtattttct
    15001 ctgaggctga atttaaaagg tgttttgctt tattgtagtc accttttttt atttccttaa
    15061 gagacatcat tacatcactt ttagcatctc ctgcttctga tattatacta aatacttttt
    15121 cttccatttc aggtaccata tccttctcct tctaatgact tgttaaaaat caaagctatc
    15181 atcatctaat gttgtagcta attctgcatt tttatttaat tcttccttct ccattatctt
    15241 aaagaatgga taatatatca aggtcataag tattatactt gcaaatacta atacgattgc
    15301 cttccaatct aatgtcatca aaaatgctgc aacccctgga ggtaaaaagc ctggtggttc
    15361 tgcaataggt aatcctacta atcctacttt taatgccata aaattaagtg ctccaaccaa
    15421 tacaggtcca aatacaaatg gtacaaacat atataggttc ataactattg gtgttccaaa
    15481 tattaccggc tcatttattc caaatagtga tggtaaaatc acaacttttc ccatactatt
    15541 aaaactctta cacttacttc ttgacataag gtacactaat cccaaagtta ttcctgaacc
    15601 agttacttgc aagaaaccat agtaaaatcc tattgtaaac acatattttg ggtctcctcc
    15661 tgctgctatc agtgttgcat tttctgccat atatgtagct gctattggca tccatatact
    15721 tgaagttatt gctgctccat gaagcccaaa gaaccataat aattgagtta taaatagtat
    15781 tatagttact gcaaaaacat tatctacact gcttatagct ggtgctaaga aattcattat
    15841 aatagctggt agtggttgac ctgagacatt tttagttatt gctgctattg ctgtaaataa
    15901 cattatacat actatcattg gagttaaatt tctaaaactt ttatttacta cactaggtac
    15961 ttcttttgga aatctaatta cgagattttt atcattcata aacttagtaa tatcaactac
    16021 taaaagtgct actaatatac ttacaaataa accttgtgca tctaaataac ttgtatctaa
    16081 tacaccatct actacttgtc cacatacaac aagttgtgca acaactgctg tcatgcctat
    16141 ttctacatga ttaagattat attttttagc tagtgcctga gctataaaaa atgctgaata
    16201 tatagataat aaactcatag taaatttatt agggataagt aatgtatcca tattttcaga
    16261 taataatgtt tttgcacttc cttcaggtaa catattgttt aatgccataa ataacatact
    16321 taaagaacca acaattatta ttggggtaat gcttatcata ccttctttta tagcttgaag
    16381 atgcctttgt ttttcaatct tttgtgctat tggaagaaga aatcttctta aattattttg
    16441 aagtgcttcc atttttattc cccccaatta tctattttta tataattcga ttgccgactt
    16501 cataacagaa ggagcatcca tacgaccata atgcttagta tctattaaac caactgctat
    16561 tttgtaattc ttacaagctt caactacatc atcttcctta aacctaattt gtggtgctac
    16621 aagtactaca tctgtatcat tagcttcaat gtatgatttt aaattttcaa atgatgttgc
    16681 ctctatattt atagttttag tttttaactt ttcatgctca ctacaaaaac ttttcatctt
    16741 ttccacaagt acacctgttg aagctccatt tgcacatact aataaaatat tcataattac
    16801 cctcctacaa tatctaacct cttttatttt ctaatttttt atcagccaat tcttactcta
    16861 attcctatca gtttttactt taattcttat tattttattt taattcttat taatatttac
    16921 tctaattctt agtactgcca atgattaaac ttgaaagccg tatctataac ttcttcttgc
    16981 ttatattttt ctaatatttt taagtatctt tctttataat cattatctac ttctttttct
    17041 ggtattacta tactagcttc atttaaaaag tggaatgaat cccttcccat ttctaatcct
    17101 ctatatgtat gcttgtcaag tgccacgtcc ataacttctg gaactttacc cattgcaaat
    17161 ccttttataa ttatattttt taataaatca cttgatctat ctttctcaca tgcacaaaga
    17221 tatcttattg catgtatgaa aaataaaggt ctgtctccat ctgcatatga atattccttt
    17281 cttacttgat ttaaattatt tatgattatt acagctgatg gatcccccat tcctatatct
    17341 tcaactgata ttgtaagtat ccttctccat agcttatctt ctaattctgg tgatgatata
    17401 tatagttcat aagcaaattc acaagcttct tccaccatat ttcttcttat agctttttga
    17461 aatgacgata ttatttcgtc tgcactaaat ccgtttcttg tagtcattct tgcccatggg
    17521 tcatttgcct ttttatctct taatatttta tcttgcatat tatttactcc tttttattta
    17581 aattttaatt atttatatta ctcatttaat aatataagca agtattatgc cagttttttt
    17641 agacacttta aaacactgtt atttcaatca tttttatcat caaaacttag atactttgtc
    17701 taagtatatt tatatgtgtc taatattaat attattttag actaaaaaaa aattaccaaa
    17761 taagttttta tactcattgg taatcttttt cgattatttc tgcatattct aatattaata
    17821 atatttgata gcactctttt tcattaattt ctatattata ttttttatct aattgagata
    17881 ctatatcttt tattttgctt agactcttgt gataatcaag tgttttttct ttatcaagct
    17941 tttcaatttc tctagtattt ccaatcaacc catctaccat gaaagctaaa tgcatcataa
    18001 gtccaattac tttatcgtat ttcttttcta tattaaatac taaaaacaat tcatcagaca
    18061 catattttat atctttaaat attctattat aattagagct ttttaaggat gtctttaaac
    18121 cttcaactac atcatcataa cctatactta tctttataat attttttaat ttattgatat
    18181 tttcatcctt atctatatct tttttgctaa tatagtcaat tcctctaata ttaattcttt
    18241 gttcattgat tactgcaaca atattactac tttctttaag tttcgtaata tttaaactta
    18301 aatctttttc tgttttatat gggacagata taatatctat tccatctaag tacctactca
    18361 tcttttcttc taatattttt cttgttttat tatctacacc ttctgaaaca tgtgatgcta
    18421 taataattgt tttagacaga ttttctttat tttgaatttc attagttcca aaatagtgct
    18481 ttctcgtgtt agtgatagag ttgtatacgt catttaaagg taatcccata ttggccttct
    18541 gaactgcttc taacacagtt aatgtcgtca ccataggaat tactcttact ccacactttt
    18601 tttctttctt tataatttca tcaaaggagt ttaatgaacc catatctgta aatagtaata
    18661 catctttatt gtctatatta ttaattaaat ttttaaaatc tacaataact tcatcatagc
    18721 ttttatctaa cttcatatcg aaagaaatag cactgcactt tccaataata tcaccaactg
    18781 cttttaccat actacttgct gtagtttctc catgcatagc aactataata ttaatgttat
    18841 tcactatttt attttgttca tcttgtttag cttgtactat gaataatgta atatatgcta
    18901 cagtttctat agataaaaat aaatcaaatt cattttcaat tattccaact atttttaatg
    18961 ctgttttaaa ttcacttctg ttatttcttc taatttgatt caaatctatg ttgtttgtag
    19021 agctactttt atccaatacg ctttttatat aaattgccat tgacttaaat attgattcac
    19081 ttatgtctat ttcttcatct tctttaataa tttgtcttat tgattcacac atgcttttaa
    19141 acttaacatt attaaataga gaagcatctg ctatattcat ttctacagat ttattaagat
    19201 tagtatttac tgcattaata atatttatat cattgtagtt aataacttct tcttctccta
    19261 atgacgtaaa tacaaaatat tctattccat gtgttataac ttcatctgct ttaatagact
    19321 tctctctata atcatcactc acttcattta tagatttatc aaaatatttt ttctctatat
    19381 aaactggttc tttattatct cttttatatc ttagatatcc atttgcaaca gctaatttta
    19441 tatcattttg aagttgacct acattatttt tacaatcata aagtaatagt gatttaatta
    19501 tttctttatg tacttttatt gaaatagaaa tactttttga ttcttccttg aaaaaatttt
    19561 tgactaattc cattctttca atcattgtcc tatctctcaa tgatggtatt tctattttca
    19621 ttggtattct tctattgaat gtatctaata gtgttgatgt cggattttct gtagtagcac
    19681 atattattaa taccttagac tctctttctt tcgttgcatc tcctagtctt ttaaatgttc
    19741 ccttatctat aaaagtaaac aacatttctt gaccttctgc tggtagtcta tgaatttcat
    19801 ctaaaaatag tatccctcca tttgcaattt ccaaaagacc ttttctggaa gattctgcac
    19861 ctgtataagc tccttgttct accccaaaaa tatgtcccat aagtaattgt gcattattag
    19921 cataatcagc acaattaaat gttacaaaag gagctttatt ttttctaatt ccactatcta
    19981 tagaataatc gtacatatat ctagcaatca tactctttcc tactcctgtt tctccataga
    20041 taatagtatg aagtccattt gtaggataga gcattgcgac cttgcatttt tctattatag
    20101 gtcttaaact atgttcttta cctattagtg tttcaaaact atcttttttt attttgtttt
    20161 ctacttttgt tccttttttt atgccaagca actcactttg tgtatcaagc aattcattct
    20221 tgttaaggtt aagatttgca gggatataat acacaggtct tccttttatc ttcgtaacca
    20281 taccctcatt gaataattgg tttaaatatg tacttatatt gtttcttgca attcctgtct
    20341 tttctgataa ttggttagct gtaatccctt tttcattttc cctatatgat gattctaaaa
    20401 ctttcattac tttatctttt ttatatatca ttacaagctc ccctacatta tagtatttta
    20461 ttaactaaaa cccctataca cactttattt tttaataaac tcttattctt taactaaggt
    20521 tataatttat caaactttcc ttactttaaa ttatagaaaa ttattgtaga aaaaataaga
    20581 ttattgctca ttttttctac attactattt ttaattttat agtactttct taacaacata
    20641 ctttacttgt ttttaatttt attatatttg aatttattat atttgaaaag tagaaataaa
    20701 aaaccctatt ttggagtagt tttaaaattt ctccaaaaat agggttttag tttgtatttc
    20761 aaataaatac ctgttcaagt atttttatac taaacaactt ttaaattttg ttgatattta
    20821 tttatttctg atttagaaga atatacaaaa tgtccatctg aaacctcaat ccaacttaat
    20881 gacttttcat ttgaacaatc atatccatta gaattatact ctattctatt tcttgactta
    20941 gcatatctag ggtcaggaac aggaattgca gaaagtagtg attttgtata tggatgaata
    21001 ggattattat acaattcatt tgaatctgcc aattctacta attttccatt atacataact
    21061 cctatacggt cactaatatg tctcaccata gataaatcat gagctataaa taaacaagtt
    21121 aaattctttt cttgttgcaa ttttttaaat aaatttacta tttgtgcttg tatagacaca
    21181 tccaaagaag ctataggctc atcagctatt ataaattctg ggtctactga aagagctcgt
    21241 gctatgccaa tacgctgtct ttgtccacct gaaaaatcag atggatactt atttgcataa
    21301 cttctatcaa gtcctactag ctttagcatc tcatatactt tattcattct atctgtttta
    21361 tttttacaga taccttgaat ttttagtggc tctgaaatta tatctgcaat tgtcatacgt
    21421 ggatttaatg atgaagtaga atcttgaaaa ataatctgca tacttttgtt tacatctttt
    21481 tttataaatt tgtacgtttt tttatctgat atgcaatttc ctttgtaaat tacttctcca
    21541 ccagtagatt catgtagtct tattatagtt ttaccagttg tagattttcc tgaacccgac
    21601 tctcctacca atccaaatat ctcaccctta tatatatcaa aacttatatc atcaactgct
    21661 tttacagtag tacttttgtc caaatgaaaa tattgcttta agttttttat ttccagtatt
    21721 ttttctctat tcattagaaa tcacccttcc acaatttact ctaactggta catctacttc
    21781 aggtgcatct gggtgcaata accaagttgc tgcactatgt gtatcattaa ttttaaacat
    21841 tggtggctct ttttcataat ctatcttaag tgcattttta ttccttattg caaaagcatc
    21901 tccttttggt gggttcaata aatttggagg cattccaggt atattatata aatagtcatc
    21961 ctgcgaatct aaagtaggta atgaacccaa caacccccaa gtatatggat gtctagggtc
    22021 ataaaatata tcctctacag ttcctatttc tacaatcttt cctgcataca taactgctat
    22081 tctatcagct atagttgcaa ctactcctaa atcatgagtt ataaatatta ttgacaaacc
    22141 tattttatgt tgtaaatcct ttattaaatc aattatttga gcttgtatag ttacatctaa
    22201 agcagttgta ggttcatcag caatcaatac atctggatta caagcaagtg ctatagctat
    22261 tactatacgt tgtctcattc cacctgaaaa atgatgtgga aattgtttaa atcttttctc
    22321 aggattatca attccaacca attcaataag ctctatggct ctcttttttg cctcactttt
    22381 acttatacct tgatgaatga ttacagcttc tgcaatttgc tttcctattg atatagttgg
    22441 attgagagat gtcatagggt cttgaaatat cattgatata ttctttcctc ttatatcttc
    22501 catctctttt tcagacttct taaccaaatc acttgattta agtaaaacct ctccattttt
    22561 aatatatcca ttgtatggga gtatcctcat caaactctta cacagtacag atttcccaca
    22621 accagattct ccaactatag ccaatgtctc accttttttt agattaaaag atacatttct
    22681 tacagcctga acttctcctt cttctacttt aaaacttaca gatagattat taacctccaa
    22741 taaatgttcc aaaaaccatc aacccctatg ctattcaaac cttagggata tatttttatc
    22801 cctaaggttt ctaattaatt tcagtattat tcaattgtcc agtcagctat gttccagaat
    22861 acacctacac catgatgacc taaaactgta tcaggtgtta atccttttat gtttggtttt
    22921 ccaacatata ttgcatctat ataagcaata aatgtataag gcatatcctt agtcatttct
    22981 acttggaatt gtttatataa ctttaatttt tcatctttat cttctgtttc tcttgctttt
    23041 tgaagtattt tatctatagt aggattagag taagcactgt aatttgcacc tttatctgtt
    23101 ccaaatactt tatatgtatg gtcatctggg tcaaatggac ttccccaacc tattaaatga
    23161 gcatcttgat tagcccaatc tgtttcagtt acaacaacag ctttagcatc aacaccaatt
    23221 tcttttaact gttgtgcaca tattttagcc atatcaactc taacttggtc actctcacct
    23281 gctgttatct cgaaagctaa cttagtacct tctttttcat agattccatc agaacctaat
    23341 ttccaaccta gcttttcaat ttcttgttta gctttttctg gattatattc aaacttttct
    23401 atatcaggat tattatatgg tcccatttgt aaaggtgaat atgctggtac accatgtcct
    23461 aataatacac tgtcaactat tgcttttcta tctattgcat agcttaaagc atttggtaat
    23521 cctttagctt ttttatcttt aaagaattta gaattaaaat tgtataatat acctctatag
    23581 tcggctgttt tcattatatt tactttaaaa ttcttttcgt ctttttcaaa gttagacata
    23641 tctttaggag ttatttgagc taggtctaat tctcctgatt ttaattgcat tgccttagcc
    23701 ttatcatctg gaacaatctt aaagactact ttatctaatc ctggttcttt tacaaaataa
    23761 tcactattct taacaagtgt tatactttga cctttgtccc atttttcaag tttaaatggt
    23821 ccagtaccta ttggtttttg attaaattca tcagtagcta tatccttacc ctccaaagca
    23881 tgttttggta atactcctac tgttaaataa tcaagcattg ctgtatttgg agcttttaaa
    23941 gtaattttta tagtattatc attaaccaca tcaatttttg ttatatcttc ataatttgat
    24001 gctatctcag aagcattatc tggattcatt atagtttcta ttgtaaactt aacatcattt
    24061 gctgtaaatt tctctccatc atgccactta acatcatctc ttaaattaaa agtatatgta
    24121 tttgttgcct catcaaattt ccagtccttt gctagacaag gaaccacctt attattttca
    24181 tcatgagctg ttaatccatt aaatattaac gaatttattt ctccatgttc atatagtgca
    24241 ggatttatac ttgtatagtc attacttcca taaacaagca cctttccatc tttaggcgta
    24301 tctgccttct tatctttgtc tcctccacta gaacaacctg ccattagact aagtatcatt
    24361 actaaactta aaacttttaa cttctttaat ttcatgatgc tccccctttt gctttttata
    24421 aaatattttt caaagctttg accccattta tttaaataga tatttcaaat acctcagtat
    24481 ttgcttattt aatactcaaa tgctgattta taaattacta gattttttat tattattctt
    24541 tcttatataa ttacctatat ttgttataca caccaatgtg gtaaccaaaa atatacccgg
    24601 aatcagtata atccaccatc tatttgaaag taatgcttcc tctgacaaag ataacatact
    24661 tccccaagaa acaatttcta ttggtaaacc aattcctaaa aagctaagtg tcgattcagt
    24721 accaatagct gcgcctatgt ttgttacaac catgaacatt attgatgcca caaaatttgg
    24781 aagtaaatgt tgctttaata catagaagaa tcctcctccc atgctcttag ctgctagtat
    24841 gtattcgcta ttttttattt gtctaacttc tgttctcact atcttagata tattcatcca
    24901 acttgttatc cctattacta tggacataga tactggattt gaatttccaa gtatagcttg
    24961 tacaaatatt ataattaata ttgaaggtat actaagtatg atttctgtaa acctcatcat
    25021 tgcatcatct acgagttcag atgccgaacc acttatacta ccataaacaa ttcctataac
    25081 agttgatatt acagtggaaa atagtcctat aaataaagat atttttcctc cataccatat
    25141 catagaatat atatctctac ccattgagtc tgttccaaat aaaaaagttt tatttggagc
    25201 taaattagaa cttgctaaat ccatgtatgt tggttcatgt gtcattataa aagatgagaa
    25261 tacacttcca atgactatga ttgataaaat aataattgat atatatggta attctttaat
    25321 ttttttagat aaggttttct ttgtttctat atgttcatct tctgctacta aaatataatt
    25381 ttctcctaca atttcaaaat cactatattg tggcttcatt agtatcacct ctatcatatt
    25441 tcattctagg gtctatttta ttgtttataa tttgagctaa catattccca aatactacta
    25501 aagcccctgt tattaagcat aaaactaata acatattata atcatgatac tttgcacttt
    25561 caaaacaaag tgttcctaac ccaggataag aaaaaacttt ttcaactaca taagttcctc
    25621 ctagtatatg aggtatcgaa atggccatta tactaatata tgatggcatt atatttctca
    25681 ggcaatgctt aaaaacaata gttctattat ttaaaccttt tgctttacat aaaagcacat
    25741 aatcttctct tatttcctct agtaatttat ttcttatcat atatgtgtaa taccatagat
    25801 ggcttaatat aagtactgta agaggtaaga ttagatgtga tatcctactt aatatactgg
    25861 actcttctcc cattgaataa gcaccactac ttggaagtat acttaagttt atactaaata
    25921 taagtatgag tactaaggca acccaaaatg atggaataca gttggttatt gttcctaatt
    25981 tgcatatgat tctatcaatg agcttatctt catgtaatgt acaaaatatt cctaacaata
    26041 aggctagcac aaaggtaagt atatatcctg aaccacctaa tattatagtg tttatataga
    26101 catcatttat aacagaagta acattttgtt tatatttaaa tgaaattcca aattcccctt
    26161 ttgatgcatt tgaaatccat tttatatatt gactgtatat tggttcatcc aaaccaagtt
    26221 ttttcatagc attttctttt tcttgtgtac tcattctttc tactccatcc ccatagtaag
    26281 agattaatgg gtctcctgga gcaagtcttg ccatgtaaaa aacaataaaa gataataaaa
    26341 acattactaa aataaactgc aacaactttt tcagtatatc ctttaacaaa ccccaacccc
    26401 cctttgttgc aataaaaaaa accacataaa agcaaacgta aagtaacgtt aaaaccttcg
    26461 tggttccatt atcattaaac aaaattaaat tttctatatt tatctatgag ttaattttag
    26521 catcatttat taactgtgta aacaaacttt ttaaaaattg ttaaaatttc atcaaattat
    26581 tttatttata cctaaaataa aatttttata ttctattctt cattattttc tataaaatta
    26641 taaaatttta ggttgactat ataagaaaag tatattatat tagtttgtat gcaaaccatt
    26701 taagaggtga ttttattgaa aagtaattat gactgtttta gaatagccat gctcttaaaa
    26761 gaactttatt ctaaaactat gtacacagta gaagaaaatt ttaaagaaaa tggattaaca
    26821 caccaacaga ttatagttat aaaactgata gctcataatc aagaacttac aatatcacaa
    26881 ctatgtgatg aaatgtcttt agctaaaggt acggtttcag gcataatcag cagattagaa
    26941 cagattggat atatagaaaa attcaagaaa tctaatgata aaagaaatac atacgttaag
    27001 tttacaacaa caggatttga atttgccaca aattttaaaa ttaaaatgca agaaagtttt
    27061 gatgatattt ttaaaaattg tgatgaaaac gaattgagtg acttagtaaa aaatcttaga
    27121 aatatattgg caaaagtaaa ggagagataa ttatgaatta taaattaata cttgcaatag
    27181 tatttataac atcagcttta attttctaca ctataggtgt atttggagaa agaaaggcaa
    27241 aaattttaaa aaagaaacat gtaattatat tttggcttgg ttttatattt gatactttag
    27301 gaacatttac aatgagtaac atagccaaca gccatacttt tgaagtaaaa tctgctttat
    27361 cacaaaacct tcatagtatt acaggtcttc ttgcaattgt gcttatgctt tttcatgcaa
    27421 gttgggctac ttttgtccta tacaaagatg atgaggaaaa gaaaaaattc tttcataagt
    27481 ttagtatagt tgtatggact atatggttag ttccatattt tataggtatg tttattggta
    27541 tggctggata gtaaaataaa aagtgtgtaa gaaatactgt aggtaaattt gtataagaca
    27601 aatttatcta catccttctt tcacactttt acatatttat ttataatact ccattatttc
    27661 tttcatgttt cttaatacct atatagaata tttaattatt tctatagtat tttattattt
    27721 tctcacactt tttcatatat atattgtttt actatttctt catatgtata tatgaaatat
    27781 tccattattt ctataaatgt tttattatct ttctcatact ttttcatata tatattgctt
    27841 cactattttt tcttatttct tcatatacat atgaaatatt tcattatttc tataatgttt
    27901 tattatcttt ctcatacttt ttcatatata ttgcttcact atttttttta cttctttatt
    27961 aaatacttat gtataacata catttaataa acgctaacta ttaaacacct aatacttgag
    28021 ttactcctgg aacttcactc accaaaacat tttcaataat agctttgatt gtcatagtcg
    28081 ctcctggaca cccactacat gccccttgta gtctaactaa aaccacacca ttttcattta
    28141 catctataag ctctacatct ccaccatctc tttgtaatac tggttttatc ttttcctcaa
    28201 gcactttttc aactttttct ctcatagcta ttccccccag aaatatttta ttagcaaaat
    28261 tataccaatg gtttaaattt ttgtccatct aatgatttat caaattcaat ttttgcttca
    28321 tcaataattt tagtatccat aaatacatca taagcactac aagccagtac tttagctgaa
    28381 tttatcatag cagaaaatcc tatatttgaa cctgctgatg aacatgactg ccatgtatga
    28441 cttgcaattc caacaggcca agctgccatt gcaaattgag ccactggtat tacataactt
    28501 acatctccaa catcagtaga accagctagt cctttatctt tgtcaccgtc aactatttcc
    28561 ttgtgtatat agctttctac aatagattta tcattttgta atgatgttgc tacacctaat
    28621 ctttcttctc tagtaagagt atcacacaac ttttttgcaa attcttcttc ttcaggagta
    28681 tttttagggc aaccaacaaa aaccatattg tcataaacta aatcagtcaa acattggttt
    28741 ggtatatagt catatattcc atctgtaacc ttatactcca tttcagtttc tgtcatcatt
    28801 gctgctcctt gagctacttt tattaatcta tcaagaacgt gttctgcatc ctttgctttt
    28861 ttacctctaa taaagtacca actttcagca aatccaggaa ctacattagg tcttccacca
    28921 ccattagtta taacatagtg cattcttata gagtcaataa catgttctct caaataatta
    28981 gctccaacat tcataatttc aacagcatca agtgcgcttc taccattatg aggagcttga
    29041 gctgcatggg ctgttatccc tttaaattta aattttacag ataagtttgc cagacttcca
    29101 cctctccaag gtgcatttat atcaaaagga tgccatgtaa atgcacaatc tacatcatca
    29161 aaacagccat ttatacacat agctgtcttt cctccacctt cttcttcagc aggacaacca
    29221 aaatatttta ttgttccatt aaatttattt tcttctatta atttttttat agaaacaact
    29281 gctcctacac ctgctacacc caacaggttg tgcccacatc catgtccagc ttttccttct
    29341 accaatggct ttctttctgc acttacacat tgtgatagct ctggtaaagc atcatattct
    29401 ccaagtatgc caatcacagg tttaccctct ccaaaacttg ctataaatcc agtaggtaaa
    29461 ttttctactt cttcaatttt aaatcctttt gactttaggt attctttttg aatgctactt
    29521 gcatactttt cttcaaaggc taattctgga ttttcccata ttttcttaga taaatcaatt
    29581 aattcttctc ttatttcttc aacattattt atgatatact ctttcataat tttcctccaa
    29641 atatatgtat ttttgatatg ctttacagat tatattatat actaacattc tatttattca
    29701 caattttttg ttaattaatt ttattcatat gctcttctat ggagtatatc ttatcttcac
    29761 tttgcctctt cataaattta atgtactcta tcttccataa agtagtttca gttttctcat
    29821 ttaacataaa ttctaatata ttaatttctc tcattctaat atcttcataa aatactacac
    29881 tacccaatat tgccaattct aattcactta atgatgcaaa caacattaaa tactcttctc
    29941 caaataaaca ttcagattca agaatatcga taaagtcttt tttagcattg atattttcct
    30001 ttattattct tattttttca attatagatg tactatctaa tatctcattg aatatctctc
    30061 taaacgattc atcatccaat ttactttcat catcaacaat ataatcttct aagtgttcct
    30121 ttttattttt actcacagtt accatacttt taaaagtgtt actttttatt gagcttagca
    30181 cagattcaat aaatatcttt tcatattttt taatatatct tattacatct tcatcttcta
    30241 tgcttaatct ttttattaat acttcaattg cttccataag tagtaaagtt atttttttat
    30301 ttattctaat ttctctgtta atttcttcaa aatcattata atccaaatta ctatctactt
    30361 cagtgttaaa actatcatct acttcaatca attcaattat attactttct tcagagtcta
    30421 taactttatc
//
LOCUS       DAEPKC010000043        30350 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.043, whole genome shotgun sequence.
ACCESSION   DAEPKC010000043 DAEPKC010000000
VERSION     DAEPKC010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 30350)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30350)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30350
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.043"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            1007..2677
                     /locus_tag="KR294_001960"
     CDS             1007..2677
                     /locus_tag="KR294_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF and EAL domain-containing protein"
                     /protein_id="HBH0240040.1"
                     /translation="MREESNSLSLDHIEIFFELLSQSTEDYIFFWDINRNKFKISSAI
                     FDEFNLSKEIESDLVNCWSKIVYPDDVQIWKDDIQELLHGKKGEHNLEYRLINKYKEI
                     VWISCRGKVYVSDDPKTIFLVGRIKNIGEKNKFDSITGTWNREQFEHKMNYLIKEKIY
                     KNGAMFIMDIDNFKNINEKYGHSYGDKVLRAIATEVLEYLPKDVRLYRLDGDEFAFFY
                     PMCTKETIEKIYEKIQMYTNTQHEIESSKYYCTVTAGVAMYPEDGDNYLDLFKHADIA
                     LDIAKISGKNRIKFFSQELYENKLKVISMQQKLRECVENNFNDFELFFQPQVNAVTKE
                     VIGAEVLLRWHSSTYGEVSPVEFIPILEQSNLIIPVGKWIIKEAVKQCKEWHKINPDF
                     KISVNVSYIQLKEDFFRDFIVECLVEYQLRPEFLILELTENCWIPDINLLNDKFISLK
                     GIGVYIAIDDFGTGYSSLNYLKELSVNIIKIERSFVKNITYNSYEYTFLEYIIKLAHI
                     INLKVCVEGIESYEEYDIVKSLGVDIIQGFLFGRPVSASEFYKFQLSK"
     gene            complement(2799..3533)
                     /gene="pflA"
                     /locus_tag="KR294_001961"
     CDS             complement(2799..3533)
                     /gene="pflA"
                     /locus_tag="KR294_001961"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HBH0240041.1"
                     /translation="MIKGKIHSIETFGTVDGPGIRYILFFQGCPLRCKYCHNRDTWDI
                     KSGKEYTVDEIITDALKYTSFMKFSGGGITASGGESTLQPEFLSELFKKAKENDIHTC
                     LDTSGFVDIETIDPVLDNTDLVLLDLKHMVEEKSIDLTGVGMDKALKLARHLESRNIP
                     VWIRHVLVPGITDDIDNLEKLGQFVATLKNVERFELLPYHSMGIHKWESLGIDYELKD
                     VPDATKEDVQKASEIISKFGVKVYNS"
     gene            complement(3693..5924)
                     /gene="pflB"
                     /locus_tag="KR294_001962"
     CDS             complement(3693..5924)
                     /gene="pflB"
                     /locus_tag="KR294_001962"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HBH0240042.1"
                     /translation="MNAWQGFKTGRWTKEINVREFIQLNYSPYEGNDSFLAGATENTK
                     KLWDEAMVLFKKERENGGTLDVDTKTVSGIAAYAPGYLDKELETIVGLQTDAPLKRAV
                     MPYGGIKMVENSCEAFGYELDPEIKDIFTKYRKTHNQGVFDVYTPEMRAARKSGIITG
                     LPDAYGRGRIIGDYRRVALYGVDALIEDKNEQKKSLEVSCMDEEVIRLREEITEQISA
                     LNELKKMAESYGFDISKPATNSKEAVQWLYFGYLGAVKDQNGAAMSLGRTSTFLDIYF
                     ERDLKAGIVTEEELQEYMDHFVMKLRMVKFLRTPDYNNLFSGDPTWVTECIGGMGIDG
                     RTLVTKNSFRMLNTLYTLGPSPEPNLTVLWSTKLPQGFKDFCSKVSIDTSSVQYENDD
                     LMRAYWGDDYGIACCVSAMRIGKQMQFFGARVNLAKTLLYAINGGVDEKSGVQVGPRF
                     EPITSEYLDYDEVMSKFEPFTDWLATLYVNTLNVIHYMHDKYSYEALEMALHDRDIFR
                     TMACGMAGLSVCADSLSAIKHAKVKTIRNEQGIAVDFEIEGDYPKYGNNDDRVDSIAV
                     ELVESFMNKIRKNKTYRNSYPTQSILTITSNVVYGKKTGNTPDGRRAGAPFAPGANPM
                     HGRDTNGALASLSSVAKLPYEHAQDGISNTFSIVPAALGKDMTERINNLSAMMDGYFA
                     QNAHHLNVNVFDRATLEDAMEHPEEYPQLTIRVSGYAVNFIKLTKEQQLDVINRTFHG
                     KMA"
     gene            6217..7278
                     /locus_tag="KR294_001963"
     CDS             6217..7278
                     /locus_tag="KR294_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium/sodium antiporter"
                     /protein_id="HBH0240043.1"
                     /translation="MEKRKSIHLHKLNIYLIGGGDRLFITVVLFLVGFLLITKGADIF
                     INCTVEIGKKTNISEIILGATIVSFATTLPEFTVSLLASIDGHTTMSLGNAVGSIICN
                     TGLALGLVVFISPFNVDKKMFFSKSLLLIVSVIVLILLSLDGVITRGDSLLLIIILIF
                     YMVNNYRSVVGKSDTKNRNIKNNTIKDISTKKGKNYRGFSVLEIVKILLLFATGLIMM
                     IIGSQILIESGVIIASFLNIPQGIVSLTIIALGTSLPEIVSSITAIRKNHHEISVGNI
                     LGANILNIVSVIAVSAIPNNIPILSQNRQLDIPFMILLLLIVIIPTLKSNRLSRIQGI
                     LMLFTYFLYISILYFMYII"
     gene            7369..8982
                     /locus_tag="KR294_001964"
     CDS             7369..8982
                     /locus_tag="KR294_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBH0240044.1"
                     /translation="MNITKFEDLPISEGIKKAIAEMGFEEPSPIQAQSIPAILSGKDV
                     IGQAQTGTGKTAAFSIPILETIDPNNRSLQAVVLCPTRELAIQVSTEIRKLAKYSHGI
                     KTLPIYGGQPIDRQIKSLKSGVQVVIGTPGRTIDHINRKTLKMDNVKMIILDEADEML
                     DMGFREDIEMILSKIPEERQTTFFSATMPRGILELTKRYQKDPEHIKVVRKELTVSNT
                     KQYYIETRSSNKLEVLCRLVDVYDPKLSVVFCNTKRKADELVGDLQARGYFADALHGD
                     LKQTQRDIVMDKFRNGTIDILVATDVAARGIDVDDVECVFNYDLPQDEEYYVHRIGRT
                     GRAGREGMSFTFVFGKEMRKMKDIERYTKSKLIKHNIPTITDVEEKKVGTFFAQVKQT
                     IEEGHLTKQLQWLEGFCNDEDYAMVDIAAALVKLSLGEEMKEEIIEEKPRRERGDRKG
                     GTGAKDGMIRLFINIGRNQRVQAKDIVGAIAGEVGIPGKVVGTIDIYDKYTFVEIPKK
                     DAKTVIEKMKDIKIKGNKINIEKANKKKK"
     gene            9257..11242
                     /locus_tag="KR294_001965"
     CDS             9257..11242
                     /locus_tag="KR294_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBH0240045.1"
                     /translation="MSMTYMDPRVFLILEMVLEEDTNTLEQFSNVLGVSTRTIRNYIN
                     QINRELKGGIAKIVKNEKGTYSIRIEDESKLIEIVNFNRGKLSNFINLNSPDERINYV
                     LDILTMTNNPITIDDLAEEICIGRTTLIKDLKKADRILAEYDLELKRKPNIGMILVGE
                     EMDIRLLILDRLYENYIDVLENVNQINLVKDYDIECLRDELKKLFKKEELYITEQVLR
                     DVERYIIMSVLRNLNGYKFEKIDKRFEVIRCSDEYTLGLKLKALLEKIFNIVLNEKET
                     IFLTMPLIGRKAPSTKLALSSIKINDSVKEVVDEVTSFLLETSGIDFKEDKKLIENLE
                     YHLYFALNRMRFNIRVKNPLLQEIKERYTFPYSVAKIAAMIIEEKFDLKICDHEIGYI
                     ALHFGSYFEKNSRKVLNVNRVAVVCGTGLGTAQLIRIKIGKILGESVEVNTFSDIEAK
                     ANLDLLKYYDLVFTTVDFKTDLDVPIFRVNALFNEESIKKEIENAILLKNSINLKSIK
                     KIEKNIPFIGKLIEEDKFFILNKSTFMENLEDMLEKLVHKGIIDIEFKKKVLKREKKS
                     STALDNYIALPHSVNTNGENLYLAFGILEKPVIWDTKEIRIIILMIIPDKNVDSTDLI
                     IKSYEEVLEVGRDKKMVEELAKVKSFDEFYKIITKRR"
     gene            11247..11681
                     /locus_tag="KR294_001966"
     CDS             11247..11681
                     /locus_tag="KR294_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator GutM"
                     /protein_id="HBH0240046.1"
                     /translation="MDPVIFIIASLITVYLLNIFLGYLQLKDFNKNYIELKRKGRVAI
                     GRKKGRISSGTIVLILINDDGVIVETRKMQGVTVLARVKSFEGLVGKSLEYIEKSDLT
                     VYNKLLKKAILDAVKQYITFEKNKCEDTNNLSTDEECRMEVV"
     gene            11710..12270
                     /gene="srlA"
                     /locus_tag="KR294_001967"
     CDS             11710..12270
                     /gene="srlA"
                     /locus_tag="KR294_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418408.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HBH0240047.1"
                     /translation="MTQFFQVLASGADSFMNLFRAGGQQFVGFVTDIVPLLVALLVTM
                     NAIINFIGTDRVERLAKKCSANIFTRYLILPVLGTFVFANPMTLSLGRFLPEKFKPSY
                     FAAASFSCHTMNGLFPHINPGELFIYLGIANGITTLGFSTADLAVRYLLVGIVANFIK
                     GVVTDYTTKFVEKQQGIALNSDIKIG"
     gene            12334..12702
                     /locus_tag="KR294_001968"
     CDS             12334..12702
                     /locus_tag="KR294_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sorbose transporter subunit IIB"
                     /protein_id="HBH0240048.1"
                     /translation="MAFNKVKIVKGSGGWGGPLIIEPTEKKNKVVYVTGGAKPETAVK
                     IAELTGCELIDGFSQGVKDDEIACVIINCGGTLRCGIYPQKKIPTINIMKTGKSGPLA
                     MFIKEDIYVSGVKPTNVEQL"
     gene            12727..13293
                     /locus_tag="KR294_001969"
     CDS             12727..13293
                     /locus_tag="KR294_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003374365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HBH0240049.1"
                     /translation="MAYDTKKKISEQSQGIVAKIGIALGNVTSTLFQAGRDTIDTLIH
                     TILPFMAFVAVLIGIINQSGIGNWVANLLTPLIGNVGGLVVLSIICSFPLLSPFLGPG
                     AVIAQIVGVLVGTEIGKGNIPPSLALPALFAINSQAACDFIPVGLGLAEAEPDTVQVG
                     VPSVLYSRFLTGAPTVLLAWLASFGLYK"
     gene            13334..13699
                     /locus_tag="KR294_001970"
     CDS             13334..13699
                     /locus_tag="KR294_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HBH0240050.1"
                     /translation="MELIYSTQINKIGDNANEFLQHNMFVTFKDNAPQELENYCYIHS
                     ENNLVKEILTDDVLSINNVDYKITSVGELVNQNLSELGHITFKFTGEKDGAIGGTLYL
                     EEKEIAPIGVGTILKIIRK"
     gene            13800..14573
                     /gene="srlD"
                     /locus_tag="KR294_001971"
     CDS             13800..14573
                     /gene="srlD"
                     /locus_tag="KR294_001971"
                     /EC_number="1.1.1.140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sorbitol-6-phosphate dehydrogenase"
                     /protein_id="HBH0240051.1"
                     /translation="MRKVALVVGGGRSLGEYLSKHLAKVGYDVAIADLNEDNAKKVAE
                     EIKTEFGCKSVGYSCNAIDERQVISTVKAIENDFDRIDLLVYNAGVAVSKKITDFGYK
                     DFKFIVDVNLNGYFLFAREVSKVMIAKGIEGRIIQINSKSGRVGSKHNSGYSAGKFAG
                     VGLTQSLALDLAEHKITVNALMLGNLLDSDMFESLIPQYAVKLGIPESEVKQVYIDKV
                     PLKRGCRFIDVANMLTFYASKEAEYCTGQSINITGGQVM"
     gene            14922..17360
                     /locus_tag="KR294_001972"
     CDS             14922..17360
                     /locus_tag="KR294_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HBH0240052.1"
                     /translation="MDIIKKLSHGCTLDCHDCCKFNVYTKGNNVVKIEGDKNHPYTKG
                     FICKKGMAHLDRLNHKDRIKTPMLKVDGVWKEISFDKAIEIMAEKLTYYKEKYTSKSV
                     MHYDQYGSGSVLKYIGDIFFNFYGGVSRHKGGPCWSAGMHAQKYDFGVAKSHAIEDML
                     NSKSIFVWGKNPAYTTIHTMQIIKKAKEKGIKIVVIDPIYTKTAQIADKYVQVNPGTD
                     GALAIAMAKIIVEDKLYDEEYINSYVIGFEEYKKYLSSLELSFLIDECGVKENDIREL
                     VDLYTNKYSSINVGYGLQKYKNGGNTIRAIDALGAITGQIGFSGGGVNYANKVYPSVI
                     NSDPYNSQSYGEDREFYVSNISKFIEESLKNTSNKVNYASDELDMALHKVNYISDELD
                     TTSNKVNYVSDELDMALHKVNYVSDELDTTSNKVNYVSDELDMALHKVNGVSDELDMA
                     LHKVNCVSDELDMTSNKVNYVSDELDMTSNKVNYVLDELDITSNKTDYISNELYNLSN
                     KSIKDNIPIKMAVITKSNMLNQLPDLVELERVFSKIEFKVCFDMFITDTVTLCDMFIP
                     CTNTLESEDIIYSSMTNPYITYNERAVKPAHKLMDEYYFFMELAKKMGLNDYPFVEKR
                     TYLEKVIEPLKRFDKNLDIEKLKNNYFTIHNPVAWEDKKFETPSGKYELYSESIKNLG
                     ISPTPVYISNKYKEIEDKNISFRLLTNHHADTLFSQHFMDKKSIAQAYINQRMAKKVG
                     IEEKDIVILRSKKAKINVQINIDDGVGNYIVKMYVGWWKKHGNPNSLTDTGISDFGGQ
                     VTYNESMVEIIRQN"
     gene            17448..17783
                     /gene="spoIIAA"
                     /locus_tag="KR294_001973"
     CDS             17448..17783
                     /gene="spoIIAA"
                     /locus_tag="KR294_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma F factor antagonist"
                     /protein_id="HBH0240053.1"
                     /translation="MVNYSLEHKNLYIEFMCSELDHHVANEIREEIDNLLSVNQVKNV
                     VFNFENINFMDSSGIGVIIGRYKKISNEGGRVSVINISSRVKKIFDLSGLNKIIGIYD
                     TYEEALSSL"
     gene            17797..18225
                     /locus_tag="KR294_001974"
     CDS             17797..18225
                     /locus_tag="KR294_001974"
                     /EC_number="2.7.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma F factor"
                     /protein_id="HBH0240054.1"
                     /translation="MNNIMEVKFSAISENESLARVIVASFAAKLDPTVDELVDIKTAV
                     SEAVTNAIIHGYEEDSSKFVFLRCEIEGNTIKIIVEDEGYGIENVEKAMEPLYTSKPE
                     LDRSGMGFTVMKSFMDDVEVSSVKDNGTRIEMTKKINVPK"
     gene            18248..19012
                     /gene="sigF"
                     /locus_tag="KR294_001975"
     CDS             18248..19012
                     /gene="sigF"
                     /locus_tag="KR294_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigF"
                     /protein_id="HBH0240055.1"
                     /translation="MEVTVAREEKKPLLSHEETLELIEKVQNGDEEAKEILISSNLGL
                     VRSVVSRFLNIGYDREDLFQLGSIGLIKSIYKFDPKFNVKFSTYAVPMILGEIKRYLR
                     DDGMIKVSRSLKQIAVKAKMESEALTKKLGREPSIEELAKAIDVEKEDLVMAMEANFN
                     VEYLQGVIHEEEGSPICLIDKISMKGESEEEKVVDNILLKDILGRLDKRERQIIVLRY
                     FEDMTQSEIGEMLNISQVQVSRIEKKVLSKLKEYIS"
     gene            19292..19729
                     /gene="spoVAC"
                     /locus_tag="KR294_001976"
     CDS             19292..19729
                     /gene="spoVAC"
                     /locus_tag="KR294_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein AC"
                     /protein_id="HBH0240056.1"
                     /translation="MDKNYKKYVDQISPKPTYLKNYTLAFIVGGIICMIGQAINDLYM
                     KVGGLDKLGASSATSITLIFIGAFLTGLGVYDLIGKRAGAGSIIPITGFANSIVSPAM
                     EYKREGYVLGVGANLFKIAGPVLVYGIGSSILCGIIYYIFKMF"
     gene            19896..20909
                     /gene="spoVAD"
                     /locus_tag="KR294_001977"
     CDS             19896..20909
                     /gene="spoVAD"
                     /locus_tag="KR294_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein AD"
                     /protein_id="HBH0240057.1"
                     /translation="MKNKRIGKRTVKLENKPTIISTGTIVGPKEGEGPLKDYFDMIMT
                     DDLYGEKTWELAESKMVETASQQAIQKAGKKLSDVNYMLGGDLINQIVPASFAARELA
                     IPFLGIYGACSTMAEGLCIGSMLIDGGFADLVLSGTSSHYCTAERQFRFPLELGNQKP
                     MTAQWTVTGAGSVLLAPNGDGPKVKYVTVGKVIDEGIDDGNNMGPAMAPAAIDTIYSY
                     FEDTNDDPNSFDIIATGDLGTLGKQIAEDFLKEKGVDISKVYTDCGIEMFNLKEQDVH
                     CGGSGCGCSATVFAGYIYDKLRKKEFNKVMLVSTGALLSPTSTLQKQTIPCVAHAVVI
                     VNE"
     gene            20923..21285
                     /gene="spoVAE"
                     /locus_tag="KR294_001978"
     CDS             20923..21285
                     /gene="spoVAE"
                     /locus_tag="KR294_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein AE"
                     /protein_id="HBH0240058.1"
                     /translation="MLMDYVRVFIVGGIICLIAQVMMDYFKMQTPYVMVTYVTTGVVL
                     TFLGLYEPLVKFAAAGATVPIIGFGYSLATGVIKSIQSDGFLGIFLGGTTATAGGIAA
                     AIFFGYIMSVVFTPKAKP"
     gene            21468..22484
                     /locus_tag="KR294_001979"
     CDS             21468..22484
                     /locus_tag="KR294_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBH0240059.1"
                     /translation="MVTIKDIARNLGISYSTVSRCLNNNPNVSEKTKKKVVEEANRLG
                     FHFNVNARNLAKKETNRIGVIFSNNFNHQDTRKFFSDIMDSSINSIETNKYDFIIQPN
                     NNISGDSNVYKMVNGQMVDGLVIVSQSIKKEEYDFLKDNNFPHVFIYFKPSFIGEVDN
                     FFWDDNVYGGYIATKHLIDHGHKDIITVTSDDKSSKMHEDRTKGYLNAMEEANLKTEV
                     IKSKMDFESQVEFLEKYIDKIKKSSAIFVQQDVPAISIIQELKTTYGINVPEDISIIG
                     YNNIELISYFRSHLSTIDDPREQVIKNGVDSLVNIINKKSTEHIPRKLYPRLIIRNSV
                     KRIK"
     gene            22859..23701
                     /locus_tag="KR294_001980"
     CDS             22859..23701
                     /locus_tag="KR294_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3100 domain-containing protein"
                     /protein_id="HBH0240060.1"
                     /translation="MKEKAGIRNAIIAAFIITILAELIGPISFKVMGINVTLLSILWA
                     IFIGMAVSPHLLGRVIPALKKFIGDNEINVSPYLLSLTLYPLGIMFGINAGPKVGILL
                     QAGPALLLQEFGHMGTMLIALPVGVALGLGRSALGGTFSLCRDTALGIIGDKYGLNSP
                     EGIGTLGTYISGSIFGTLLFSFLAPVGVLLGFHPYALAMASGMGSGSMMGAATASLMN
                     TVPQMSEQILAYSATSGLITAVTGIYIELFLSLPVANYYYSKVAPVIERFRGRKTRRT
                     SNKL"
     gene            23716..24180
                     /locus_tag="KR294_001981"
     CDS             23716..24180
                     /locus_tag="KR294_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240061.1"
                     /translation="MEKTFKTIMEQIKIVLFIYIIICFGQMIALKTQAQDLLIGSVSG
                     FLLVIIAIIIKNFVKKPNLPGFAWATLVAFVLSLPISPVGDIIATNVGKINFMSTVTP
                     LLAFAGISVGNQLDILKTLSWKLVVISFIVMTSTYFGSAFISQTVLRLNGML"
     gene            24167..25339
                     /locus_tag="KR294_001982"
     CDS             24167..25339
                     /locus_tag="KR294_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBH0240062.1"
                     /translation="MECFKEVVNMNELKAKIKEEIKLLSEEKKTSFEKVSDYLFSNPE
                     LAFEEYKSQKALCDLLEENEFNVTKGVGGLETSFEAVYSNGTNGKTVAFLAEYDALPG
                     MGHACGHNIIGTSSVGAGIILKEIMKKHNIEGTVKVFGTPAEERVGGKITMIKEGVFN
                     NVDAALILHPSDASMPDDISFAQVNLKFDFTGKASHAAAFPWEGKSALSGVIALFNSV
                     NSMRLHLKDYARVHGIITDGGSIHNIIPEKSTAIFNVRALSIEYLNEICEMLKNCAKG
                     AAISTGTNVEIVQLDEIYKEIKNDSELVNIVRQNFEVLGEDYVERDLSQGIGSTDTGN
                     LTHEIPAIQAYIKLKENTATHTDEFAVAAGGEEGRVALIKAIKVLAMCGVDILYSK"
     gene            25383..26318
                     /locus_tag="KR294_001983"
     CDS             25383..26318
                     /locus_tag="KR294_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1177 domain-containing protein"
                     /protein_id="HBH0240063.1"
                     /translation="MILKQVIEVYDILDKANANGEEVKTYLQGYGEVDVTVKELSSSK
                     GSTDLVKLTIPGKNGKLKGGDAPTLGILGRLGGIGARPEVIGFVSDGDGALVAIAVAA
                     KLLDMQRKGDILDGDVVISTHICPDAPTKEHYPTPFMDSPIDMMTMNENEVDSSCDAI
                     LSIDTTKGNRVINTRGFAISPTVKEGYILKTSDNLLDIMQTVTGKSPFVFPLSIQDIT
                     PYGNNLYHLNSILQPAVATDAPIVGVAITTEMPVAGCATGATNFSDLDSAGRFAIEVA
                     KLFGRNKCDFYDKEEWEMLIKRYGKLNRFQTFGIQ"
     gene            complement(26592..29285)
                     /locus_tag="KR294_001984"
     CDS             complement(26592..29285)
                     /locus_tag="KR294_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase domain-containing protein"
                     /protein_id="HBH0240064.1"
                     /translation="MNNDNDKNGNKIRRKKVSSSGNTNKPINRTSANKTRSTKNKKKS
                     KKSDKFKKLRVFGIVFLVLLVVGTAGTAGLVFASLRDVTPVTEAVLDKQTNQTTTIKY
                     ANGKTLSTAPSVNKKTPVPLDKISPYLQHAVIAIEDERFYEHKGVDIKGLFRSVLKTL
                     TGTKQGGSTIPMQVSKMLLTTEQQTIPRKIKDIYYAHEMSKTVSKDKILETYLNNFFV
                     GRGLAGAEAGARGYFDKSAADLTLAESALLAGSTKNPSRFSAYKTSKLEGNETKEDLE
                     NKLLFFVNTTDDDLDDPTQVDFDMIEKIKSWELISNDTYRQLKAGTLVVRKAVSNPEA
                     KKRQEIVLKKMLELKYIKQSEYDEAIKAKIEIKLPQSSDKVSSSVEDLIESEVINALM
                     EQGHTNDEAQNLFYNGGLIVNTTIDPKMQDALEEEFDRNSNFPGHMVGPDGVSQPQAA
                     MVILDYKNGEIRALAGGRNISGRKTLNRATNPHQPGSSIKPLAIYTPAIDTLKITQAT
                     ALSDSRGGYKFKENNEWNPRTTTAGHGSMSLRKALAKSSNTIAVKTAEMLGDSYDECV
                     DIMMDYLKNFGITTLKNNHSGSSEASDRKFPSLTLGGMANGITPLQMAAAYGTLANHG
                     IYVEPSIFTTITTFDGQLLVKNAPEEHKVVDPEVAYVVTDMLESVITEGTGGVATLPK
                     GMPVAGKTGTTNSAYDAWFVGYTPYYVGATYIGDDAGRKDDSGNTIKRREVPHGSTST
                     AKLWEKIMEKIHANLTVTEFEVPKNVYFTKINLEDGGKQSSGSKAAFIEGTAPTKVSS
                     QPSSEDTKKPDNNQPEENNNNNNNTGDNGGGSTPPDNGGNNGGGSTTPPDNGGNNGGG
                     STTPPDNGGNNGGGSTTPPDNGGNNGGGSTTPPDGGGTPAT"
     gene            29499..30197
                     /gene="yunB"
                     /locus_tag="KR294_001985"
     CDS             29499..30197
                     /gene="yunB"
                     /locus_tag="KR294_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein YunB"
                     /protein_id="HBH0240065.1"
                     /translation="MNRIVDRKTKNEFRKIIAIFLVILFLSVFIGSFIYIDKTLRPTI
                     TVLAETKALELANRSINKAVAEMVEGKINYEDLMDIQLDNNGKITMIQANTIMMNEIA
                     SAIALEIQDELKKDKTASSYIPIGTALGSPILAKYGPKLEVSIEPIGTVSVNFKTEFE
                     SSGINQTRHRIYLEAQTQVKVVIPLITSTKQIKAQIPICETIIVGDVPESYVNIPEKN
                     LGNVLPNTGKNTNK"
BASE COUNT        11520 a         3603 c         5226 g        10001 t
ORIGIN      
        1 tagatatttt tctaaaaatt atctatgtta atagttaaat ttatgaacat tttttgtttt
       61 tatgttagga tatttcttag aaatgaaata cttcttaatt tgatttgata tgtatatttt
      121 tatagctatt ttattataaa aaaaaagaac ccttttataa caaatggaaa ctatggatgt
      181 aataattaaa ataaaaaata ttattttata tttataaaca ttgacattct aattttgtag
      241 tgtaatcgta ttttttatta attcttacaa aatcaatgaa aataagtata tccattttaa
      301 agtacataaa tttaaaaatc cagaaaaata tacttaaatt atgtaagtaa aagaggggtt
      361 gaatcagttg aaaatgtaat attagcaaat agtacatcaa tcctatatac cctgtaagca
      421 actctatttt catgtactaa aaatgtacct attttattaa ctgaaaagaa taaattaaat
      481 gtaagtacat aagaagatag aaaaaattaa aaacaaaaaa tatttatata aataaatata
      541 aaaaatgata taatccctat taaaaaattt atagatgatg aagaaatatc aaaatcttat
      601 attataggaa gagacacttc tttgccaaaa tctatagaaa aacaatacca aatccaaaga
      661 gaataggcgg agaaaaaaat aaaataaatt caagagtaat agaaaagttt tatagaataa
      721 agaactgata actctttata taacgaaaaa tagaatttta agagaaaatg atttaataac
      781 tgatttaaca tggtgtttta gcaggtaaaa ataaatcacc agtaatgatt atagaaaaat
      841 tactttatga atctcaaaaa acttagttaa gagtaagaga tttgataaga taactaaagt
      901 tggggaaatg tgtttgatga gacaaaaaat tagtaaaata gtataatcta aataaggata
      961 ttttgttgat taaactacac taatagtaat attgtagggg gaaaagatga gagaagaatc
     1021 gaactcttta agtttagacc atatagaaat tttctttgaa cttttatctc aaagtacaga
     1081 agattatata tttttttggg atataaatag gaataaattt aaaatttctt cagcaatttt
     1141 tgatgaattt aacttaagta aagagataga atctgatttg gtcaattgtt ggagtaaaat
     1201 tgtttatcca gatgatgttc aaatatggaa agatgatata caagaattac tacatggaaa
     1261 aaaaggtgag cacaatttag aatataggtt gattaataaa tataaagaaa tagtatggat
     1321 ttcttgtaga ggtaaagttt atgtgtcgga tgacccaaaa actatatttc tagtcgggag
     1381 aataaagaat attggtgaaa aaaataaatt tgattctatc acaggaacgt ggaatagaga
     1441 acaatttgaa cataaaatga attatcttat aaaagagaaa atttataaaa atggtgctat
     1501 gtttattatg gatattgata attttaaaaa tataaatgaa aaatatggac attcttatgg
     1561 tgacaaagtg ttgcgtgcaa ttgctactga agtactggaa tatcttccaa aagatgtaag
     1621 attgtatagg ttagatggag atgaatttgc atttttttac cctatgtgta ctaaagaaac
     1681 tatagagaaa atatatgaaa agatacagat gtatacaaat actcagcatg aaattgaatc
     1741 aagtaagtac tattgcacag tgactgcagg cgttgctatg tatccagaag atggagataa
     1801 ttatttagat ttatttaaac atgctgatat tgcattggat atagcaaaaa ttagtggtaa
     1861 aaatagaatt aagttttttt cacaagagct ctatgaaaat aaactaaagg taatttcaat
     1921 gcaacaaaaa ctaagagagt gcgttgaaaa taattttaat gactttgagc tgttttttca
     1981 accccaggta aatgctgtta caaaagaggt aataggggca gaggtacttt taagatggca
     2041 ttcgagtact tatggagaag tatctcctgt tgaatttata ccaatactag aacagagtaa
     2101 tttaattata ccagttggga agtggattat aaaagaagct gtaaaacagt gtaaagaatg
     2161 gcataaaata aatccagact ttaaaatatc tgtaaatgta tcgtatattc agttaaagga
     2221 agattttttt agagatttta tagtagaatg tttagtagag tatcaattaa gacctgaatt
     2281 tttaattttg gaattaacag agaattgttg gataccagat ataaatttac taaatgataa
     2341 atttattagt ttaaagggta taggagtata tattgcaata gatgactttg gtacaggata
     2401 ttcatcttta aattacctta aagaactgtc tgttaatata ataaaaattg aaagaagttt
     2461 tgttaagaat attacatata atagttatga atatactttt cttgaatata ttattaaatt
     2521 agctcatatt ataaatttaa aagtttgtgt tgagggaata gagtcttatg aagagtatga
     2581 tatagtaaaa agcttagggg tagatattat tcagggtttt ttatttggaa gacctgtaag
     2641 tgcctctgaa ttttataaat ttcagctatc aaagtgatgt atataaaatg agatatatag
     2701 tatataaaaa tagggcaaag tggaagtttt gaagtttatt aaaaatttac actttaccct
     2761 attttgttat gtcttctata aaggattaat atactacact aactattata tactttcact
     2821 ccaaatttag agattatttc actagctttt tggacatctt ccttagtggc atcaggaaca
     2881 tcttttagtt cataatcgat acctaaactt tcccatttgt gtattcccat agaatggtat
     2941 ggtagcaatt caaatctttc tacatttttc aatgtagcta caaattgacc tagtttttct
     3001 aaattatcta tatcatcagt aatgccagga actaaaacat gtcttatcca tacaggaata
     3061 tttcttgatt ctaagtgtct agcaagtttt aatgccttat ccataccaac accagtcaaa
     3121 tcaatagatt tttcctcaac catatgtttt aaatcaagta aaaccaaatc agtattatct
     3181 aaaactgggt ctatagtttc tatatctaca aatccagatg tatccaagca agtgtgtata
     3241 tcattttctt ttgctttttt aaataattca cttaaaaatt ctggttgaag agtggattca
     3301 ccaccagagg cagttatacc tccaccagaa aacttcataa aagaagtata cttaagagca
     3361 tccgttatta tttcatcaac tgtgtattct tttcctgatt taatatccca tgtatccctg
     3421 ttatgacagt atttgcatct aagaggacac ccctgaaaaa ataatatata tcttattcct
     3481 ggtccatcta cagtaccaaa cgtttctata gaatgtatct ttcccttaat catagagttc
     3541 acctcacaat atattttaat aaccttatca atagttataa tatttctcta aaaaaggcca
     3601 tcttatacca gaaataattc aaatataaga tagcctttta tttttatttt ttacacagta
     3661 gtaatcttag ttaaagtata aaaatttaaa gactaagcca ttttaccgtg gaatgttctg
     3721 tttataacat ctaattgttg ctctttagtt aattttatga agttaactgc atatccagat
     3781 actcttatag ttaattgtgg atattcttct ggatgttcca tagcatcttc taaagtagct
     3841 ctatcaaata catttacatt taagtgatga gcattttgag cgaagtatcc atccatcatt
     3901 gcagaaagat tgtttattct ttcagtcata tcttttccta aagcagcagg tactatagag
     3961 aaagtattag atataccatc ttgagcatgt tcatatggta atttagcaac tgaagataat
     4021 gaagctaaag caccattagt atctctacca tgcattgggt tagcaccagg agcaaatgga
     4081 gcaccagctc ttctaccatc tggtgtatta ccagttttct taccataaac aacatttgaa
     4141 gttattgtaa gtatagattg agtaggataa gaatttctat aagttttatt ctttcttatt
     4201 ttattcataa agctttcaac taactctaca gctatactat caactctatc atcattattt
     4261 ccgtattttg gataatctcc ttctatttca aaatcaacag ctattccttg ttcatttcta
     4321 atagttttaa ccttagcatg ttttatagca gataatgagt ctgcacaaac tgataatcca
     4381 gccataccac aagccatagt tctaaatata tctctatcat gtaatgccat ttctaatgct
     4441 tcataagaat atttatcatg catataatgt attacattta aagtatttac atataatgtt
     4501 gctaaccaat cagtgaatgg ttcaaattta ctcataactt catcataatc taagtactca
     4561 gaagttatag gttcaaatct tggtccaact tgaacaccag atttctcatc tacaccacca
     4621 tttatagcgt ataataaagt tttagctaag ttaactctag ctccaaagaa ctgcatttgt
     4681 ttaccaattc tcattgcaga tacacaacaa gctataccat agtcatctcc ccagtatgct
     4741 ctcattaaat catcattttc atactgtact gaacttgtat ctatagatac tttagaacag
     4801 aaatctttga atccttgagg taatttagtt gaccatagaa ctgttaagtt tggttctgga
     4861 gaaggcccta atgtatatag agtatttaac attctaaatg agtttttagt aactaatgtt
     4921 ctaccatcta ttcccatacc tcctatacac tcagttaccc aagttgggtc tccagagaat
     4981 aagttattgt aatcaggagt tcttaggaac ttaaccattc ttaatttcat aacaaaatgg
     5041 tccatatact cttgtaattc ttcttctgtt acgattccag cttttaaatc tctttcaaag
     5101 tatatatcta agaaagtaga tgttctacct aaagacattg cagcaccatt ttggtcttta
     5161 acagcaccta aataaccaaa gtataaccat tgtacagctt cttttgagtt agttgctggt
     5221 tttgatatat caaatccata agattcagcc atttttttaa gttcatttaa agctgatatt
     5281 tgctcagtta tttcttctct taatctgata acttcctcat ccatgcaaga aacttctaat
     5341 gatttctttt gctcattttt atcttctatt aaagcatcaa caccatatag agcaactctt
     5401 ctgtagtcac caattattct acctctacca taagcatctg gaagacctgt tattatacca
     5461 gattttctag cagctctcat ttctggagta taaacatcaa aaactccttg gttgtgtgtt
     5521 tttctgtatt tagtaaatat atcttttatt tctgggtcta attcatatcc aaaagcttcg
     5581 catgaatttt caaccatctt tataccacca tatggcatga cagctctttt taaaggggca
     5641 tccgtttgta acccaactat tgtttctaat tctttatcta aatatcctgg agcatatgca
     5701 gctattccag aaacagtttt tgtatcaaca tctaaagtac caccattttc tctttctttt
     5761 ttaaatagga ccattgcttc gtcccataat tttttagtat tttcagtagc accagctaag
     5821 aaagagtcat ttccctcata tggagaatag tttaattgta taaactctct aacatttatt
     5881 tctttagtcc atcttcctgt tttaaatcct tgccatgcat tcattaagta tttcctcctt
     5941 agatttaaat gataaataat actattaaaa ttaattttta tatacttaat ttattttata
     6001 tattttttta aaaatatatt ttctaatata ataatatcat attattcgta tcctgtatac
     6061 ataaaaaata aaaaattgtc gctttaaagt ataaaacaga ttatatgtta ataatgtggt
     6121 gaaattatac ccatatataa ataaaataaa acaaataaat agctaattaa ggagaaaata
     6181 ttttttattt tttgtttagg ataaataaat tttattatgg aaaaaagaaa aagcatacat
     6241 cttcacaaat tgaatattta tttaataggg ggaggtgata gattgtttat cacagtggta
     6301 ttatttttag taggtttcct attaattact aaaggcgcag atatctttat aaattgcact
     6361 gtagagatag gtaaaaaaac gaatatatca gaaattatac ttggagctac tatagttagt
     6421 tttgcaacaa cattacctga atttacagtg tctctacttg cttctattga tggtcatact
     6481 actatgagtt taggaaatgc agttggttct ataatatgta atacaggatt agcattaggg
     6541 ttggttgttt ttataagtcc atttaatgta gataaaaaaa tgtttttttc taagtcttta
     6601 ctattaatag tatccgttat agttttaatt ttattgagtt tagatggagt tataacaaga
     6661 ggtgattcat tattacttat aataatatta atcttttata tggttaataa ttatagaagt
     6721 gtcgttggaa aatctgatac taaaaataga aatattaaaa ataacactat taaagacata
     6781 tctactaaaa aagggaaaaa ttatagaggt ttttccgtat tagaaattgt aaaaatacta
     6841 ttactttttg ctacaggatt gataatgatg ataataggtt cacaaatcct tatagagagt
     6901 ggagtaataa tagctagttt tttaaatata cctcaaggta tagtaagttt aactataata
     6961 gcacttggaa cttctctgcc agagatagtt tcgtcgatta ctgctataag aaaaaatcat
     7021 catgaaatat cagtaggaaa tattttgggt gcaaacatat tgaatatagt atcagtaata
     7081 gctgtatcag caataccaaa taacatacca atactatctc aaaatagaca attggatata
     7141 ccattcatga tattattatt attaatagta ataataccaa cacttaaatc taatagactt
     7201 agtagaatac aaggtatatt gatgttattc acatattttc tgtacatatc aattttgtat
     7261 ttcatgtata ttatttaact atactgttta aaatattaat tgcagaatat cctaaaaaag
     7321 tatataatgg ataggttaag attaattgat aacggagagg aataatatat gaatataaca
     7381 aagtttgaag atttaccaat aagtgaggga ataaaaaaag ctatagctga aatggggttt
     7441 gaagaaccat ctcctataca agcacagtct atacctgcga ttttgtcagg taaagacgtt
     7501 ataggacaag ctcaaactgg tacgggaaaa acagctgctt ttagtatccc tatactagaa
     7561 acaatagacc caaataatag aagtttacaa gctgtagtgc tttgtccaac aagagaactg
     7621 gcaatacaag tatcaacaga aataagaaag ttagctaagt attcgcacgg aataaagaca
     7681 ttacctatat atggtggtca gccaatagat agacaaataa aatctctaaa gagtggtgtg
     7741 caagttgtaa taggtacacc aggacgtaca atagaccata tcaatcgtaa aacattaaag
     7801 atggataatg taaaaatgat tatattagat gaagcagatg aaatgctaga tatgggattt
     7861 agagaagata tagaaatgat tttaagtaag attccagaag aaagacaaac aactttcttt
     7921 tcagctacta tgccaagagg aattttggaa ttaactaaga gatatcaaaa agacccagag
     7981 catataaaag ttgttagaaa agaacttaca gtttcaaata caaagcaata ctatatagaa
     8041 actaggtcat caaataaatt agaagtatta tgtagattag tagatgtata tgaccctaaa
     8101 ctatctgttg ttttctgtaa tactaagaga aaagcagacg aattggtagg agatttacaa
     8161 gcaagaggat attttgcaga tgcattacat ggtgacttaa aacagactca aagagatata
     8221 gtaatggata agtttagaaa tggtacaata gatatacttg ttgctactga tgttgcagct
     8281 agaggtatag atgttgatga tgttgaatgt gtattcaact atgacttacc acaagatgaa
     8341 gagtattacg ttcatagaat tggtagaact ggtcgtgctg gtagagaagg tatgtcattt
     8401 acttttgtat ttggaaaaga aatgagaaag atgaaagata tagaaagata tactaaatct
     8461 aaactaataa agcataatat accaacaata actgatgttg aagagaaaaa agtaggtact
     8521 ttctttgcac aagttaaaca aactatagaa gaaggtcact taactaaaca attacaatgg
     8581 ttagaaggtt tctgtaatga tgaagattat gcaatggttg atatagctgc tgcacttgta
     8641 aaactatctc taggtgaaga aatgaaagaa gaaataatag aagaaaaacc tagaagagag
     8701 cgtggagata gaaaaggtgg tactggagct aaagatggta tgattagatt atttatcaat
     8761 attggtagaa atcaaagagt acaagcaaaa gatatagttg gtgccatagc tggagaagtt
     8821 ggaataccag gtaaagtagt aggtactata gatatatatg ataagtatac ttttgttgaa
     8881 atacctaaaa aagatgcaaa aacagtaatt gaaaagatga aagatattaa gataaaaggt
     8941 aataagatta atatagaaaa agcaaacaag aagaaaaaat aacgtatagt atacaaaact
     9001 ataattagaa aatatataaa ataatatatt ggatatttaa aaagcctgat gtgttttcaa
     9061 aacagatagt agataatctg taagagttaa cagcataagg cttttcttgt tttatatgat
     9121 gttataattt tccagattgt tgtgaaaaat gtatattagt tccttttttt caaatctgat
     9181 ttgaaaaaga gaatattaat tatctatata gtttagatta taataaaaaa tgtaagataa
     9241 caaaggggag aaaaagatgt caatgactta tatggaccct agggtttttt tgattttaga
     9301 aatggtgtta gaagaagaca caaatactct agaacaattt tcaaatgttt tgggtgttag
     9361 tactaggact atcagaaact atataaacca gattaatcga gaattaaaag gtggtattgc
     9421 taaaatagtt aaaaatgaaa aaggtacata tagtataaga attgaggatg aaagtaaatt
     9481 aattgagatt gtaaatttta atagaggaaa gctatcaaat tttataaatt taaattcacc
     9541 tgatgaaaga ataaattatg ttcttgatat tttaactatg accaacaatc caattaccat
     9601 agatgatttg gctgaagaga tatgtatagg aagaacaaca ttaataaagg atttaaaaaa
     9661 agcagacaga attttagctg aatatgattt agaattaaaa aggaagccaa atataggtat
     9721 gattttagtt ggtgaagaaa tggatataag attattaatc cttgatagat tgtatgaaaa
     9781 ttatattgat gtcttggaaa acgttaatca gataaattta gttaaagatt atgatattga
     9841 atgtcttaga gatgaattaa aaaagttatt taaaaaagaa gaactctaca taacagaaca
     9901 ggtcttgaga gatgttgaaa gatatataat catgtctgtc ttaagaaatc taaatgggta
     9961 caaatttgaa aagatagata agagatttga agtgataaga tgttcagatg aatatacttt
    10021 aggattaaag ctcaaagctt tattggaaaa gatatttaat atagttttaa atgaaaaaga
    10081 aaccatattt ttgacaatgc cattaatagg tagaaaagct cctagtacaa aattagcact
    10141 tagcagtata aagataaatg atagcgtaaa ggaagttgta gatgaagtaa ctagtttttt
    10201 attagagacc tcagggattg attttaaaga agataaaaag cttatagaaa atttggaata
    10261 tcacttgtat tttgcactta atagaatgag attcaacata agggtaaaaa atcctctttt
    10321 acaagaaata aaggaaagat atacatttcc atatagtgtt gcaaagatag ctgcaatgat
    10381 aattgaggaa aagtttgact tgaaaatatg tgaccacgaa ataggatata tagcattaca
    10441 ttttggaagt tattttgaaa aaaattcaag aaaagttcta aatgtaaata gggtagctgt
    10501 tgtttgtgga acaggtcttg ggactgcaca acttattaga ataaagatag gaaaaatact
    10561 tggagaaagt gtagaagtaa atactttttc tgatatagaa gctaaagcta atttagattt
    10621 attaaagtat tatgatttag tatttacaac agtagatttc aaaacagact tagatgttcc
    10681 aatttttaga gtaaatgcgt tatttaatga agaaagtata aagaaagaga tagaaaatgc
    10741 aatacttttg aaaaatagta taaatcttaa gtctataaaa aagattgaaa aaaatatccc
    10801 ttttataggt aaattaattg aagaggataa gttctttata ttgaataaga gtacgtttat
    10861 ggaaaattta gaagatatgt tagaaaaatt agttcataaa ggaattattg atatagagtt
    10921 caaaaaaaag gtattaaaaa gagaaaagaa atcttcaaca gcattagata attatatagc
    10981 attgcctcac tcagttaata ctaatgggga aaatctttat ctggcatttg gaatattaga
    11041 aaaaccagtg atttgggata caaaggaaat tagaataata atattgatga taattccaga
    11101 taagaatgta gatagcacag acctgataat aaaaagttat gaagaagtac ttgaagtagg
    11161 gagagataaa aagatggtag aagaacttgc taaggtaaaa tcatttgatg aattttataa
    11221 aataattacc aagaggaggt aataatatgg acccagtaat ttttattata gcatcactta
    11281 ttacagtgta tttattaaat atttttcttg gatacttaca gcttaaagat tttaataaaa
    11341 attatattga actaaaaaga aaaggaagag tggcaattgg cagaaaaaaa ggaagaattt
    11401 catcaggtac aattgtgttg atacttataa atgatgatgg tgtgattgtc gagactagaa
    11461 aaatgcaagg tgttacagta ttggcaagag taaagtcatt tgaaggtttg gtaggaaaga
    11521 gcttagagta tatagaaaaa tcagatttaa ctgtttacaa taaactactt aaaaaagcaa
    11581 tactagatgc agtcaaacag tacataacat ttgagaaaaa taaatgtgaa gatacaaata
    11641 atctgagtac tgatgaagag tgtaggatgg aagtagttta aaaaaatata tttataagga
    11701 ggagttaata tgacgcaatt ttttcaagta ttagcaagtg gtgcagatag ttttatgaat
    11761 ttatttaggg caggtgggca acaatttgta ggttttgtaa cagatatagt accactttta
    11821 gtagcattat tagttacaat gaatgcaatt atcaacttta ttggtacaga tagagtcgag
    11881 agacttgcaa aaaaatgttc tgcaaatata tttactagat atttgatatt accagtcctt
    11941 ggtacatttg tatttgcaaa cccaatgaca ctatcattag gaagattctt gccagaaaag
    12001 tttaaaccta gttactttgc agcagcaagc ttttcatgcc atacaatgaa tggattattc
    12061 ccacatatca atccaggtga actatttata tatctaggaa ttgcaaatgg tataacaact
    12121 ttgggattct caacagcaga tttagcagtt agatatttgt tagtgggtat agttgcaaac
    12181 tttattaaag gtgtagttac tgactataca acaaaatttg tagagaaaca acaaggaata
    12241 gcattaaatt cagatataaa gattggataa ttactttaag gtataaataa atttttcaaa
    12301 taaaaagata gtgtatagag gaggataaat tatatggcat ttaacaaagt taaaatagta
    12361 aaaggttctg gaggatgggg tggaccattg ataatagaac caacagaaaa gaagaataag
    12421 gtagtatatg tgactggggg agcaaagcca gaaactgcag taaaaatagc tgaacttaca
    12481 ggatgtgagt taatagatgg attttcacag ggtgttaaag atgatgaaat cgcatgtgta
    12541 ataataaatt gtggtggaac attgagatgt ggtatatatc ctcaaaagaa aataccgact
    12601 ataaatataa tgaaaacagg aaaaagtgga ccattagcaa tgtttataaa agaagatata
    12661 tatgtttcag gggtaaaacc aacaaatgta gagcagttat aattgaggta gtaggaggga
    12721 agaaatatgg cttatgatac taaaaagaag ataagtgagc agagtcaagg aattgttgca
    12781 aaaataggta tagcactagg aaatgtgaca agtactcttt ttcaagctgg tagggatact
    12841 atagatacat taatacatac tatactgcct tttatggctt tcgttgcagt cctaataggt
    12901 ataataaatc aatcgggtat aggaaattgg gtagccaatt tacttactcc attaatcgga
    12961 aatgttggag gtttagttgt cttatcaata atatgttcat ttccgttgtt gtctccgttt
    13021 cttggaccag gagctgttat agctcagata gtgggggtat tggttggtac agaaatagga
    13081 aaaggaaata ttccaccaag tttagcatta ccagcattgt ttgcaataaa ctcacaagca
    13141 gcttgtgact ttataccagt aggtcttggt cttgcagaag ctgaacctga tacagttcaa
    13201 gtaggagttc cgtcagtttt atattctaga tttttaacag gtgcaccaac tgttctatta
    13261 gcatggttag caagctttgg gttatataaa tagaagaata ctttataaat aattagagag
    13321 aggttcagtt gatatggaat taatatacag tactcaaata aataaaatag gagataatgc
    13381 aaatgaattt ttacaacata atatgtttgt aactttcaaa gataatgctc ctcaagagtt
    13441 agaaaattac tgttatatac attctgaaaa taatttagta aaagaaatac ttacggatga
    13501 tgtgctatca ataaataatg ttgattacaa aattacttct gttggtgagt tagtaaacca
    13561 aaatctttca gaattaggtc atataacatt taagtttaca ggtgaaaaag atggagcaat
    13621 tggaggaacc ttatatcttg aagaaaaaga aatagcacct attggcgtag gtactatact
    13681 aaaaataatt agaaaataaa atttaaaacg aatctaatca tattataagt aaattataga
    13741 taaaagtcaa tttaactaat caagttaact tttaatgtga taaaaaaggg gaaatgaaaa
    13801 tgagaaaagt ggctttagtc gttggaggag gaagaagttt aggtgaatat ttatctaaac
    13861 atttagctaa agtaggttat gatgttgcta ttgcagattt aaatgaagac aacgcaaaaa
    13921 aagtagctga agaaataaaa actgaatttg gttgtaaatc tgtaggatat agttgtaatg
    13981 ccatagatga aagacaggtt ataagtactg tcaaagctat tgaaaatgat tttgatagaa
    14041 tagatttatt agtgtacaat gcaggagtgg ctgtaagtaa aaaaataact gattttggat
    14101 acaaagattt taaatttatt gtagacgtaa atttaaatgg gtactttcta tttgcaagag
    14161 aagtatctaa agtcatgata gcaaaaggta ttgagggtag aataatacag ataaattcaa
    14221 aatcaggtag agtgggaagc aagcataatt caggatattc agcaggtaaa tttgctggag
    14281 taggacttac tcaaagttta gcgctagatt tggcagaaca taagataact gtaaatgcac
    14341 tgatgctcgg taatttactt gattctgata tgtttgaaag tttaattcct caatatgcag
    14401 taaaattggg aatacctgaa tcagaagtca agcaagttta tatagataaa gtacctttaa
    14461 aaagagggtg tagatttata gatgttgcaa atatgcttac attttatgct tcaaaggaag
    14521 ctgaatactg cactggtcaa tctataaata ttactggtgg acaagttatg taaggttttt
    14581 atggagtgtc tcaagatgaa ctctttagtt catgaggcac ttttttgtat aaaattaaat
    14641 atattttcag catttaaaca atgaaaaaga ggtttatctt tattttgaga tagcctcatt
    14701 tttgtaatta aaaaacatag tgtttaagta aacatataag attgttagtt ttttaaaaga
    14761 gaatttttta ataatattat atttatgaag tatttttaaa cttaatttga taaaatatag
    14821 ctatgtttta tatactgtag ttttgaacat agaaagttta ataaattata gtatatatgt
    14881 taatttttaa taaggtaaga aagtagaaag aaggatattt tatggatata ataaaaaaat
    14941 taagtcatgg gtgtacatta gattgtcatg actgttgtaa attcaatgtt tatactaaag
    15001 gaaataatgt agtaaaaatt gaaggagata aaaatcatcc ttatacaaaa ggttttatat
    15061 gcaaaaaagg gatggcccat ttagatagat taaatcataa agatagaata aagactccta
    15121 tgcttaaagt tgatggagta tggaaagaga tttcttttga taaagctata gaaataatgg
    15181 cagaaaagct tacatactat aaagaaaagt atacatcaaa gtctgtcatg cattatgacc
    15241 aatatggaag tgggtctgtg ctaaaataca taggagatat attttttaat ttttatggag
    15301 gtgttagcag acataagggt ggtccctgtt ggagtgcagg gatgcatgct caaaaatatg
    15361 attttggagt agctaagagt catgctatag aagatatgtt aaatagtaaa agtatatttg
    15421 tttggggaaa aaatccagca tatactacaa ttcatactat gcaaataatt aaaaaagcta
    15481 aagaaaaagg gataaagata gtagtgattg accccatata tacaaaaaca gctcaaatag
    15541 cagataagta tgtacaagta aatcctggaa cagatggagc tttagctata gctatggcaa
    15601 aaattatagt ggaagataaa ttatatgatg aagaatatat aaactcgtat gttattggtt
    15661 ttgaagaata taaaaaatat ttatcttcat tggaattaag ttttttaatt gatgaatgtg
    15721 gtgttaaaga gaatgatata agagagttag tggatttata tactaacaaa tattcaagta
    15781 taaatgttgg atatgggctt caaaaatata aaaatggtgg aaacacaata agagcaatag
    15841 atgctttagg tgctataact ggtcaaatag gatttagtgg tggaggggta aactatgcta
    15901 ataaagttta tccgagtgtt ataaattctg acccttacaa tagccaatca tatggtgaag
    15961 atagggagtt ttatgtaagt aatatcagta aatttataga agaatcttta aaaaatacat
    16021 caaataaagt aaattatgca tcagatgaac ttgatatggc attacataaa gtaaattaca
    16081 tatcagatga acttgataca acatcaaata aagtaaatta tgtatcagat gaacttgata
    16141 tggcattaca taaagtaaat tatgtgtcag atgaacttga tacaacatca aataaagtaa
    16201 attatgtatc agatgaactt gatatggcat tacataaagt aaatggtgta tcagatgaac
    16261 ttgatatggc attacataaa gtaaattgtg tatcagatga acttgatatg acatcaaata
    16321 aagtaaatta tgtatcagat gaacttgata tgacatcaaa taaagtaaat tatgtattag
    16381 atgaacttga tataacatca aataaaacag attatatatc aaatgaattg tataatttat
    16441 ctaataagtc aatcaaagat aatattccta taaagatggc tgtgataact aaaagtaata
    16501 tgctgaatca actgccagat ttagtagaat tggagagggt gttttcaaaa attgaattta
    16561 aagtatgttt tgatatgttt ataactgata cagttacttt atgtgacatg tttataccgt
    16621 gtacaaatac actggagagt gaagatataa tttatagctc aatgaccaat ccatatataa
    16681 cctataatga aagagctgta aagccagcac ataaattgat ggatgaatat tacttcttta
    16741 tggagctagc taaaaagatg ggattaaatg attatccttt tgtagaaaag agaacttatt
    16801 tagaaaaagt gattgaacca cttaagcgtt ttgacaaaaa tctggatata gaaaaactta
    16861 aaaacaatta ctttactata cataaccctg ttgcttggga agataagaag tttgagactc
    16921 catctggaaa atacgagctt tattcagaaa gtataaaaaa cttgggaata agtccaacac
    16981 ctgtatatat aagcaataaa tataaagaaa tagaagataa aaatatttct tttagattat
    17041 taactaatca tcatgcagat actttattta gtcagcattt tatggacaaa aaatctatag
    17101 ctcaagcata tataaatcag agaatggcta aaaaagtagg tattgaggag aaagatattg
    17161 tgatattgag gtcaaaaaaa gcaaaaataa atgtacaaat aaatatagat gatggagtag
    17221 gtaattatat agtaaaaatg tatgttggtt ggtggaagaa acatggaaat cctaatagtt
    17281 taacagacac tggtatatca gattttgggg gtcaggtaac atataatgaa agtatggtag
    17341 aaataatacg acaaaactag ttaaatttca ttgaaggaat aaaaatataa ttatagaatt
    17401 gattaaaagt tactattttt acaaaactat tgaaggaggg atttttgatg gtaaattatt
    17461 ccttagaaca taagaatcta tacatagaat ttatgtgctc agaactagac caccatgtag
    17521 ccaatgaaat aagggaagaa atagataact tattaagtgt aaatcaagta aaaaatgttg
    17581 tatttaattt tgaaaatatt aattttatgg attcttcagg tataggcgtc atcataggta
    17641 gatataaaaa gatttctaat gaagggggac gagtttcagt aattaatata agttcacgag
    17701 ttaagaagat ttttgattta tctgggttaa ataaaattat tggcatttat gatacgtatg
    17761 aagaagctct aagttctttg tagggaggag tatgtgatga ataatattat ggaagttaaa
    17821 ttttcggcaa tatctgaaaa tgaaagttta gcaagagtta tagtagcatc ctttgcagct
    17881 aagttagacc caacagtaga tgagttagta gatataaaaa ctgctgtctc tgaggctgtt
    17941 acgaatgcta taatacatgg atatgaagaa gacagttcta agtttgtttt cttaagatgt
    18001 gagatagaag gaaatactat aaagattata gttgaagatg aagggtatgg aatagaaaat
    18061 gtggagaagg caatggaacc actttataca tcaaaaccag aacttgatag atcaggaatg
    18121 ggattcacag taatgaaaag ctttatggac gatgtagagg taagttctgt aaaagataat
    18181 gggactagaa ttgaaatgac taaaaaaata aatgtgccta aataaagtcc aaaagtgagg
    18241 ttttattatg gaagtaactg ttgccagaga agaaaaaaaa cctcttctta gtcatgaaga
    18301 gactctagaa cttattgaaa aagttcaaaa tggagatgaa gaggcaaaag aaatattaat
    18361 atcaagcaat ttaggtctag ttaggagcgt tgtatctaga tttttaaata taggatatga
    18421 tagagaagat ttatttcagt taggttctat aggcttaata aaatcaatat ataaatttga
    18481 cccaaaattt aatgtaaaat tctctactta tgcagtacca atgattttag gtgaaataaa
    18541 gagatactta agagatgatg gtatgataaa agtatcaagg tcgttaaagc aaatagctgt
    18601 aaaggcaaag atggaaagtg aagctttaac taaaaaatta ggtagagagc cgagtataga
    18661 agaattagct aaagcaatag atgtagaaaa agaagattta gtaatggcta tggaagctaa
    18721 tttcaatgtt gagtatttgc aaggagttat tcatgaagag gaaggttctc caatatgcct
    18781 tattgataaa ataagcatga aaggagaaag tgaagaagaa aaagtagtgg ataacatatt
    18841 gttaaaagac atacttggaa gactggataa gagagagcgt caaataatag ttctcagata
    18901 ctttgaagac atgactcaaa gtgaaatagg agagatgctc aatatatcac aagttcaagt
    18961 atctaggata gagaagaaag tattgtctaa gttaaaagaa tatatatcgt gataatactt
    19021 atgatatgta gaataacaaa atataataaa tatattacta aaataaaatg taataacttt
    19081 ttatgttaag tttttaaatt attaaaagat attaaaataa taaaaagcat taaaaaagta
    19141 aaaatataaa aacaaggtgt ctttatggaa aaatagattt tttctttatt agacatcttt
    19201 tttatttttt gaccaaactt tagatagtca aaataaataa taggtttatt tttttaaaat
    19261 taacaaataa tactttagag aggtgtttag tatggataaa aattataaaa aatatgtaga
    19321 ccaaataagc ccaaaaccta catatttaaa aaactataca cttgcattta ttgtaggtgg
    19381 aattatttgt atgatagggc aagcaataaa tgatttgtat atgaaagttg gaggtcttga
    19441 taaactaggt gctagttctg caacatcaat aacattaata tttatagggg catttttaac
    19501 tggattagga gtctacgacc taataggaaa aagagctgga gctggttcta taattccaat
    19561 aacaggtttt gctaactcaa tagtatctcc agcaatggag tataaaagag aaggctatgt
    19621 attaggtgta ggtgcaaact tatttaaaat tgcaggacca gttttagttt atgggatagg
    19681 ttcttctatt ttatgtggaa ttatttatta tatttttaag atgttttaga tgatttttat
    19741 ttaatttaaa ttttattaat tatgaagaag gtataaaatc tgaaaatagc tactaaagta
    19801 actaattgaa aaataattgt gcagatttaa ttaaaatttt taattaatat taaaaatttg
    19861 aatagtaaaa tgcaaaatta aaaaggtgtg aaaatatgaa aaataaaaga attggaaaaa
    19921 gaacagtcaa gttagaaaat aaaccaacca taatatcaac tggaactata gtaggtccta
    19981 aggaaggtga aggaccacta aaggactatt ttgatatgat tatgactgac gatttatatg
    20041 gtgaaaagac ttgggaatta gctgaaagta aaatggtaga gactgcatct caacaagcta
    20101 tccaaaaggc aggtaaaaaa ttgtcagatg taaattatat gctaggtggc gatttaataa
    20161 atcaaatagt tccagcatca tttgcagcaa gagaactggc tattccattt ttaggtatat
    20221 atggagcttg ttctacaatg gcagaaggtc tttgtatagg ttctatgctt atagatggtg
    20281 gttttgctga tttagtactg tcaggtacat caagtcacta ttgtacagca gaaagacaat
    20341 ttagattccc acttgaactt ggaaatcaaa aaccaatgac agcccagtgg acagttacag
    20401 gagcaggaag tgtattatta gctcctaatg gagacggtcc aaaagtaaag tatgttactg
    20461 ttggtaaagt aatagatgag ggtattgatg atggtaataa tatgggacca gctatggctc
    20521 cagcagcaat agatactatc tattcttact ttgaagatac taatgatgat ccaaatagct
    20581 ttgatataat tgctactgga gatttaggta ctcttggaaa acagatagca gaagactttt
    20641 taaaagaaaa gggtgtagat atatcaaaag tttacactga ctgtggtata gagatgttta
    20701 accttaaaga acaagatgtc cattgtggtg gaagtggatg tggatgttca gctacagtat
    20761 ttgcaggata tatatatgat aagttgagaa aaaaagaatt taacaaagta atgcttgtat
    20821 caacaggagc actactttca ccgacaagta cactacaaaa gcagacaata ccatgtgttg
    20881 cacatgcagt agtaatagta aatgagtagg aagtgatata atatgttaat ggactatgta
    20941 agagtattta ttgtaggtgg aattatatgt ttaatagccc aagtaatgat ggattatttc
    21001 aaaatgcaaa ctccatatgt tatggtaacg tatgtaacaa ctggtgtagt tttaactttt
    21061 ctaggtcttt acgagccatt agttaagttt gcagcagcag gtgcaacagt tcctataata
    21121 ggatttggat attcacttgc tacaggagta ataaaatcaa ttcaaagtga tggtttttta
    21181 ggtatttttt taggaggtac aactgctaca gctggtggaa tagcagcagc tatattcttt
    21241 ggatatatta tgtcagtagt atttactcca aaagcaaaac cataaatctt tattaaaaga
    21301 ataataagtt tttgaaataa taacttttta taaagcaggt ggatatcttt tagattccac
    21361 ctatttttta tataaagaag cgtttacata attgaagttg acaattattt acaacatagt
    21421 gtagtattat attatcaaaa taaaatgaag tgaagtaggg gataaagatg gtaactatta
    21481 aagatattgc aaggaatcta ggtatcagtt attcaactgt ttctaggtgc ttaaacaata
    21541 atcctaatgt atctgaaaaa acaaaaaaga aagtagtaga agaggcaaat agactagggt
    21601 tccattttaa tgtaaatgca agaaatttag caaaaaaaga aactaacagg ataggggtaa
    21661 tcttttcaaa taattttaat catcaagata ctagaaagtt ttttagtgat ataatggata
    21721 gttctataaa ttctattgag actaataaat acgattttat aatacagcct aataataaca
    21781 ttagtggtga tagtaatgta tataaaatgg taaatggaca aatggttgac ggattagtaa
    21841 ttgtgtctca atcaataaaa aaagaagagt atgatttttt aaaagacaat aattttccac
    21901 atgtatttat atattttaaa ccatctttta taggagaagt agacaatttc ttttgggacg
    21961 ataacgtgta tggaggttat atagctacca agcatttaat tgaccatggt cataaagata
    22021 taataacagt aacttcagat gataagagtt caaaaatgca tgaagataga accaagggat
    22081 atttgaatgc tatggaagag gcaaatttaa agacagaagt cattaaatct aaaatggatt
    22141 ttgaatctca agttgaattt ttagaaaaat acattgataa aataaaaaaa tcttcagcta
    22201 tatttgtaca acaagatgta ccagcgattt ctataataca agagttaaaa actacttatg
    22261 gtataaatgt accagaagat atttccataa tagggtataa taatattgaa ttaatatcat
    22321 attttaggtc gcatttatca acaatagatg acccaagaga gcaagttata aaaaatggag
    22381 tagatagttt agtaaatata ataaataaaa agagtacaga acacattcca agaaaattat
    22441 atccaaggtt aataatacga aatagcgtta aaagaataaa gtagtaagct tttaagtatc
    22501 aaaagtttat taaaaatatt atagattatg tgaagttttt taacaaataa tataaataaa
    22561 aattaaaagg agtaggtgta tataagtaca ttgtactcct ttatttattg agatagtttt
    22621 tataatatga atgaataatt ttattcaatt atttgaaaat ccgttatttt aacaatataa
    22681 attaataaat tatttgtatt ttatatcatg aatctataat atttttttga ttcataacta
    22741 aaagtatata aaaatgatga ataaatatat attatacatt atcaatgata ggttatataa
    22801 taaaatcact aacaattata ttataagaaa attataaaaa ttacaaggag gtatagaaat
    22861 gaaagaaaaa gcagggatta gaaatgccat aatagcagcc tttataatca caatattggc
    22921 agaattaatt ggacctattt catttaaagt tatgggaatt aatgtaactt tacttagtat
    22981 actatgggct atattcatag gaatggctgt ttctcctcat ttattaggga gagttatacc
    23041 agccttaaaa aagtttatag gggataatga aataaatgta tctccatatt tattatcttt
    23101 gacactatat ccattaggga taatgtttgg aattaatgca gggcctaaag ttggtatatt
    23161 acttcaagca ggaccagcac ttttattaca agaatttggt catatgggta caatgttgat
    23221 agcattacct gttggagtag cattaggtct tggaagaagt gcattaggtg gtactttttc
    23281 attatgtcgt gacacagcac taggaattat tggagataag tatggattaa actcaccaga
    23341 aggtatagga acactaggaa cttacataag tggtagtata tttggaacat tattattttc
    23401 atttttagca ccagtgggtg tacttttagg atttcatcca tatgctttag caatggcatc
    23461 aggaatgggt agtggttcaa tgatgggagc tgcaacagca tcattaatga atacggttcc
    23521 acaaatgtca gagcagattt tagcatattc agctactagt ggattgatta cagctgttac
    23581 tggaatatat atagaattat tcttatcttt accagtagcc aactactatt atagcaaagt
    23641 agctccagtt attgaaagat ttagaggaag aaaaacaaga agaacaagta ataaattgta
    23701 aaggaggata tatatatgga aaaaactttt aagactatta tggagcagat aaaaatagta
    23761 ttgtttatat atattattat ttgctttgga caaatgatag cacttaagac tcaggctcaa
    23821 gatttgttga ttggaagtgt atctggattt ttgttggtga taattgctat tataataaag
    23881 aattttgtta aaaaacctaa tttaccaggt tttgcatggg ctacattagt tgcattcgtt
    23941 ttatcgcttc caatatctcc agtgggggat atcatagcaa caaatgtagg gaaaatcaat
    24001 tttatgtcta cagtaacacc attattagct tttgcaggaa tctctgtagg taaccaatta
    24061 gatatattaa agactttgag ttggaagtta gtagttatat catttatagt tatgacatct
    24121 acttactttg gttctgcttt tatatctcaa acagttttaa gattaaatgg aatgctttaa
    24181 ggaggtagta aatatgaatg aattaaaagc aaaaattaaa gaggaaataa agttattatc
    24241 tgaagagaaa aagacatcat ttgaaaaagt ttctgactat ttattttcaa atccagaatt
    24301 agcatttgag gagtataagt cacaaaaagc attatgtgat ttgttagaag aaaatgaatt
    24361 taatgtaact aaaggtgtag gaggattaga aacatctttt gaagctgtgt attcaaatgg
    24421 aactaatggg aaaacagttg cttttttagc tgaatatgat gcacttccag gaatgggaca
    24481 tgcatgtggg cacaatatca tagggacaag ttctgttggt gcaggtatca tattaaaaga
    24541 aatcatgaaa aaacataata tagaagggac tgtaaaggtt tttggaacac ctgcagaaga
    24601 aagagtaggt ggaaaaataa ctatgattaa agaaggtgta tttaataatg tagatgctgc
    24661 attaatttta catccaagtg atgcttcaat gcctgatgat atatcatttg ctcaagttaa
    24721 tttaaaattt gattttactg gtaaggcatc acatgctgct gcttttcctt gggaagggaa
    24781 aagtgcctta agtggagtaa tagcactatt taacagtgta aatagcatga gattacatct
    24841 taaagattat gcaagagtac atggaattat aactgatgga ggtagcatac ataatataat
    24901 tcctgaaaaa tctacagcta tatttaatgt aagagcttta agcatagaat atttaaatga
    24961 gatttgtgaa atgcttaaaa attgtgctaa aggagctgca atttctactg gaactaatgt
    25021 agaaatagtt caattagatg aaatatacaa agagattaag aatgattctg aattagtgaa
    25081 tatagttaga caaaattttg aagttttggg tgaagactat gttgaaagag atttaagtca
    25141 aggtataggt tcaactgata caggaaattt aactcatgag atacctgcaa tacaagcata
    25201 tataaaatta aaagaaaata ctgcaactca tacagatgaa tttgctgttg cagctggtgg
    25261 tgaagaaggc agagtagcac ttataaaagc aattaaggtg ttagcaatgt gtggagtaga
    25321 tattttgtat agtaaataat atataatttt aaaatatatt aagaaaggaa atcggattag
    25381 acatgatatt aaaacaagta atagaggttt atgacatttt agataaagca aatgctaatg
    25441 gggaagaagt aaaaacttac ttacaaggtt atggtgaagt agatgtaact gtaaaagaat
    25501 tgtcttcaag taaaggctca acagatttag taaagcttac aattcctggg aaaaatggaa
    25561 aattaaaagg tggagatgct cctactcttg gcattttagg tagactagga gggattggag
    25621 caagaccaga agttataggt tttgtttcag atggtgatgg agcattggta gcaattgcag
    25681 tggctgctaa acttttggat atgcaacgaa aaggggatat attagatggt gatgttgtaa
    25741 tttcaaccca tatttgccca gatgctccaa ctaaagaaca ctatcctact ccttttatgg
    25801 attctccaat tgatatgatg actatgaatg aaaatgaagt tgatagtagt tgtgatgcaa
    25861 tactttctat agatactact aaaggaaata gagtaatcaa tactagagga tttgcaatat
    25921 cgccaactgt taaagaaggc tacatattaa aaactagtga taacctttta gatattatgc
    25981 agactgtaac agggaaatct ccatttgtat tccctttgtc tattcaagat ataacaccat
    26041 atggaaataa tctgtatcac ttaaatagta ttttacaacc agcagtagct acagatgcac
    26101 caatagtagg agtagcaatt acaacagaga tgcctgttgc tggatgtgct acaggtgcaa
    26161 ctaattttag tgatttagat tcagctggga gatttgcaat tgaagttgcc aagctatttg
    26221 gtagaaataa gtgtgatttc tatgataaag aagagtggga aatgcttatt aagagatatg
    26281 gcaaattaaa tagatttcaa acatttggta tacagtaatt agaaaaatat taagtttata
    26341 taatttgtga tataactatt taagaatata taaacaatta ggaataaaag taagaataaa
    26401 gcacttagtt aaaaacttta aaaataaaat atttatttgt ttatataaaa aggaggattc
    26461 tggttattgg gattctcttt tttatgaata caaataatat attgtaatta taaaaaaagg
    26521 agcgtttcaa agtgattttt ttaatcacct tgagacaact ccttatattt ttatttaaat
    26581 tctatttttt attaagttgc tggagttcca ccaccatcag gaggagtagt agagccacca
    26641 ccattatttc caccattatc aggaggagta gtagagccac caccattgtt tccgccatta
    26701 tcaggaggag tagtagagcc accaccatta tttccgccat tatcaggagg agtagtagag
    26761 ccaccaccat tgtttccgcc attatcagga ggtgtagaac cgccaccatt atcacctgtg
    26821 ttattattgt tattattatt ttcttctggt tggttattgt ctggtttttt tgtatcttca
    26881 gatgatggtt gagaacttac tttagtagga gcagtacctt caataaatgc tgctttagag
    26941 ccagaagatt gctttcctcc atcctctaaa ttaatttttg taaaatatac atttttagga
    27001 acttcaaatt cagtaaccgt taaattagca tgtatttttt ccataatttt ttcccatagt
    27061 tttgcagtac tagtacttcc atgtgggact tctctacgtt ttatagtgtt accagaatca
    27121 tcttttctac cagcatcatc tccaatataa gttgcaccaa cataataagg agtgtaaccg
    27181 acaaaccaag catcatatgc actatttgta gtacctgttt tacctgctac aggcattccc
    27241 tttggaagtg tagcaacacc accagtacct tcagtaatta cgctttctaa catatctgta
    27301 acaacataag ctacttcagg gtctacaact ttatgttctt caggagcatt tttaactaat
    27361 aattgaccat caaaggtagt tatagtagta aaaatagaag gttctacata aataccgtga
    27421 tttgccaatg taccataagc agcagccatt tgaagtggag taataccatt cgccatacca
    27481 cctagtgtca atgatgggaa ttttctatca cttgcttcag atgaacctga gtgattattc
    27541 tttaaagttg ttataccaaa gttctttaag taatccatca ttatatctac acattcatca
    27601 taagagtctc caagcatttc agcagttttg acagctatcg tgtttgaaga tttagcaagt
    27661 gctttacgta aactcataga accatgacca gcagtagtag ttcttggatt ccattcatta
    27721 ttttctttaa acttatatcc tcctcgagaa tcacttagag cagttgcttg tgttattttt
    27781 agagtatcaa tagctggcgt atatattgct aaaggtttta tagaagaacc tggctgatga
    27841 gggttagtag cacgatttaa agtttttcta ccacttatat ttcttcctcc agctagtgct
    27901 cttatttcac catttttata atctaagatt accattgcag cttgcggttg gctaactcca
    27961 tcaggaccga ccatatgtcc tgggaaattg ctatttctat caaattcttc ttctaaagca
    28021 tcttgcattt tagggtctat agttgtgttt acaattagac caccattgta gaataagttt
    28081 tgagcttcat catttgtatg tccttgttcc attaaagcat ttataacttc actttcgata
    28141 aggtcttcta cagatgaaga aactttatct gatgattgag gcaattttat ttctatttta
    28201 gctttgattg cttcatcata ttcactttgt tttatatatt tcaattctaa cattttcttt
    28261 aaaacaattt cttgtctttt tttagcttca ggattactta cagcctttct aacaactaat
    28321 gtacctgctt ttaattgtct ataagtatca ttagatataa gctcccaaga ttttattttt
    28381 tcaatcatat caaagtccac ttgagtaggg tcatctaaat catcatcagt tgtgttaaca
    28441 aaaaataata atttattctc taaatcctcc ttagtttcat ttccctctaa cttagaagtt
    28501 ttataggctg aaaatcttga tggattttta gttgaaccag caagaagtgc tgactctgct
    28561 agagtaaggt cagctgcaga cttatcaaaa taaccacgtg caccagcctc agcacctgct
    28621 agacctctac caacgaagaa gttatttaaa taagtttcta gtattttatc tttacttact
    28681 gttttactca tctcatgtgc atagtaaata tcctttattt tacgaggtat agtttgctgt
    28741 tcagttgtta acagcatttt ggatacctgc ataggaatag tactaccacc ttgcttagta
    28801 cctgtaaggg tctttaatac tgacctaaat aaacctttaa tatcgacacc cttatgctca
    28861 taaaaacgct catcttctat tgcaattaca gcatgttgaa gataagggga aatcttatct
    28921 aatggaacgg gtgtcttttt atttacactt ggagctgtag ataatgtttt tccattagcg
    28981 tatttaatag tagttgtttg gttcgtctgt ttatctaaaa cagcttctgt aactggagtt
    29041 acatctctta gtgacgcaaa tactagacca gcagtacctg ctgtaccaac aactagtaaa
    29101 actaaaaata ctatcccaaa tactcttagt tttttaaatt tatcgctttt tttagatttt
    29161 ttcttgtttt ttgttgaacg agtcttgtta gctgaagttc tattaattgg tttatttgta
    29221 ttaccagatg agctaacttt ttttctcctg attttatttc catttttatc attatcgtta
    29281 ttcataagat tttaacctcc ttacttaatg caatattata acacaaatag gagtagtttt
    29341 gtaattaata gaaaaaatga atttgctata atattctgta cattgtatat gtataaacgt
    29401 aatatattaa aaagtctata tttttatttt atttattttt gacaaatatt ataaaaatta
    29461 tgccaaagct acatataaat aaataggagg ggataatttt gaatagaata gtagatagaa
    29521 aaacaaaaaa tgaatttaga aaaatcatag ctattttttt agtaattctt ttcttgtctg
    29581 tatttatagg cagttttata tatatagata aaactttaag accgacaata acagttttag
    29641 cagagactaa agctcttgaa ctagcaaata ggtcgataaa taaagctgtt gctgagatgg
    29701 tagaaggaaa aataaattat gaagatttaa tggatataca acttgataat aatggtaaaa
    29761 taactatgat acaagcaaac actataatga tgaatgaaat tgcatctgca atagctttag
    29821 aaatacaaga tgaattaaaa aaggataaga cagcaagttc ttacatacct ataggaacag
    29881 cattaggaag tcctatatta gctaaatacg gtcctaaact tgaagtatct attgaaccta
    29941 taggaacagt atcagtaaac tttaaaacgg aatttgagtc ttcaggtata aatcaaacta
    30001 gacatagaat atatttagaa gctcaaacac aagttaaagt agtaatacca cttataactt
    30061 caacaaaaca aattaaagct caaataccta tttgtgaaac tataatagta ggtgatgttc
    30121 cagaaagtta tgtaaatatt ccagaaaaaa atctaggaaa tgttttacct aacactggaa
    30181 agaataccaa caagtaatat aaagttgtat atttttaaat aaattcaaaa taatagttta
    30241 taaataaaat ttttggaaat aatattaata taattttaat aaaaatttat attttatact
    30301 atgtaaaata tctaatatat ttggtctgta ggttaaataa aagtaccttt
//
LOCUS       DAEPKC010000044        29897 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.044, whole genome shotgun sequence.
ACCESSION   DAEPKC010000044 DAEPKC010000000
VERSION     DAEPKC010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 29897)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29897)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29897
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.044"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            44..265
                     /locus_tag="KR294_001986"
     CDS             44..265
                     /locus_tag="KR294_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240066.1"
                     /translation="MNVNNHKCPECGEHSKKFEIVEENEDCVIFECYTCGTISILKYC
                     ENCKEFVFVNIPNNVETYEYCCGKCNNKI"
     gene            771..1640
                     /locus_tag="KR294_001987"
     CDS             771..1640
                     /locus_tag="KR294_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBH0240067.1"
                     /translation="MDYKTIILNRKSVREYKNTDIKEEYLSEIKKYSESCKKLVPEID
                     VDVRIMNRSEVFNNLDKVAGYKGNMIDSPSYIIILSDIKDNYIENSGYIGESIIFKVT
                     ELGIGSCWVTFEDGKKVKEKLGINSDKEVTGIIAIGYGENVSNAKVLNATKTGQNYSK
                     SDMQVVTDKGSTRLGVEDVVYMNEWGNVASIEILEERALLDAFHYARLAPSTLNRQPW
                     RFIVDGGTVVLAVRKDGHTNLYEEKIDIGIVMLYFATIISATMFDLKWNLGTPDKDYK
                     VPEDYKIVGYCNI"
     gene            1866..2732
                     /locus_tag="KR294_001988"
     CDS             1866..2732
                     /locus_tag="KR294_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBH0240068.1"
                     /translation="MEWINKLNQAITYIEENLESGVDYAEAAKIACCSTFHFQRMFSY
                     IAEVPLSEYIRRRRMTKAAFELQNSNIKILELSEKYGYDSPTSFNRAFQNIHNISPSA
                     ARAKGVVLKAYPKMTLSIYVKGNIEMQYRIVEKKGFRIVGIKESMNMIVEECFEKVPK
                     LWAKCIKNGTIDKLSELINNEPCGLLGVSVCTNSKGLDYYIAAPTDKPVLEDTHEYLI
                     PSGTWAVFECVSPMPNALAIQELQKRIITEWLPSSGYVYANLPDIELYPNGDINAPDY
                     TTEVWIPIQKPS"
     gene            2924..3121
                     /locus_tag="KR294_001989"
     CDS             2924..3121
                     /locus_tag="KR294_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004631111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0240069.1"
                     /translation="MKNRLEEIRKERGIKQEELASILQVSRQTIGSLENGRYNPSIIL
                     AFKIARYFDMSIEEIFIYEEE"
     gene            3124..3567
                     /locus_tag="KR294_001990"
     CDS             3124..3567
                     /locus_tag="KR294_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240070.1"
                     /translation="MKKNMLYVGIIYFICGILLVLLATFTEFSFEAFIWGLSGAALGP
                     GVCMILQYMYWSKPERAVDYEEKIKNQRIEMNDERRIMLRDKAGRITNQIMCYVLVIL
                     IFIVSILSVFSVMVISKWVLVVLGLLILFQFICSVVVYNKLDKRL"
     gene            complement(3754..3841)
                     /locus_tag="KR294_001991"
     tRNA            complement(3754..3841)
                     /locus_tag="KR294_001991"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(3805..3807),aa:Leu,seq:caa)
     gene            3993..6641
                     /gene="polA"
                     /locus_tag="KR294_001992"
     CDS             3993..6641
                     /gene="polA"
                     /locus_tag="KR294_001992"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HBH0240071.1"
                     /translation="MEKKLIIIDGNSIINRAFYALPEMNNKEGLKTNAIYGFTTMLFK
                     MIDIYKPTHISVAFDRKAPTFRHLEYKDYKAGRKGMPDELAEQLQPLKDLLDKFRINR
                     LEIDGYEADDIIGTVSKKAEENGYKVYIVTGDKDAIQLASDNTTTLITKKGVGEVEEY
                     NFNSVIEKYEMTPTQFIDLKGLMGDKSDNIPGVPGIGEKTGIKLIKEFSSIENLIENT
                     DKLKGSVKKKIEENKEIAIQSKRLATIIRDVPIEVDLDSMIFGDYDKDELLDKFRYFG
                     FTSLLSRLVDLVDSDDTEHVEEKIEILKLKDIEKFIDEVNKKGQVILKTVRGQGNILE
                     KNIIYIFISVDGEKIYYVDSNEVSKLDSIFSNNEIKKYGYNLKDDYISLKPYNINLEN
                     MYFDITIAEYLIDSTSSTSYDCSAIAMKYLSKKVKSKEELLGKGVKSKNYEDLEFEDL
                     AEYMGQIICTVKETVPMMERSLMDMSMDGLFYHVEMPLVEVLGHMEYEGIKVDKSILD
                     ELSVEFKEIIATLEKEIYELSGEPFNINSPKQLGVILFEKLELPIIKKTKTGYSTNAD
                     VLEKLRDKHPIIDKITEYRQIVKLNSTYVEGLLNIINPESNRIHSSFNQTITTTGRIS
                     STEPNLQNIPIKMEMGRKIRKVFIADDNCKLVDADYSQVELRVLAHMSQDENMIEAFK
                     HHEDIHTKTASQVFNVPMEDVTSELRGAAKAVNFGIIYGKSDFGLADDLNIPVPKAKE
                     YIESYFAKYHKIKEFMDTTVEKASEDGYAVTILNRRRYIPEIKSSNFMERNRGKRFAM
                     NAPIQGSAADIIKIAMINVHKKLEENNLKSKLILQVHDELIVEAIDDEIDIVKKIVKE
                     EMENAVNMDVHLDVDLNVGSSWYETK"
     gene            6650..7252
                     /locus_tag="KR294_001993"
     CDS             6650..7252
                     /locus_tag="KR294_001993"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HBH0240072.1"
                     /translation="MLILGLTGGIGCGKSSLSNIFRNLNIPIVDADIISRKIFEDKLL
                     LEKVFVHFGQSIKNDDGTLNRKALGKIVFSDEEKLKELNNLTHPRIREKIISEIEKLR
                     KKGENIVVLDAAILVESGFLDMVDKLLVVTCKQEVQISRIQKRDNCSEQEALSRINSQ
                     MSQEEKSKYGDYIIDNSGTITELESKAHKFIEYMKENWRE"
     gene            7245..7799
                     /locus_tag="KR294_001994"
     CDS             7245..7799
                     /locus_tag="KR294_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HBH0240073.1"
                     /translation="MNSKKVLILSIFIILFGALLMESKVIHKFLYPKKYSEYVEKYSK
                     EFNLDENIVYSVIKAESKFNSSAVSKKEAKGLMQILDITRDWGAEELNLKNVDIFDPE
                     TNIRLGCWYLSKLYKEFGKLDLVIAAYNGGSGNVKKWLENNEYSKDGENLHDIPFKQT
                     SKYVEKVKNNYEHYNKIYGKKGKN"
     gene            7799..9514
                     /locus_tag="KR294_001995"
     CDS             7799..9514
                     /locus_tag="KR294_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBH0240074.1"
                     /translation="MKRIKVLTVVLAITLMVAGCSNTKTKQSSSDSSLQSQSSIDAKY
                     INLTMVTPKTINPITNTDKSVGYIMNLVYDSLFTIDENYNVIPQLVKEYNIAQDGMSI
                     DIKLKDAKWHDGKNITSNDVNYTIGLIQKSADSPYNEFTKNIASVNIKSDKDFTIKFK
                     ARYAFSIDSLIFPIVSQNHLDSKDVNDKNNNMIGNGKYKIESYTEREGMVLSVNKDYY
                     EEVPKTMKNIKVGMVPNEDARTSMVMALDSDITNVTLNDLSKFQEKEFNITKYQGRDY
                     ECVLFNYNNPFFKDVNFRKAIAHSIDKDRIISEGYMDDATPVNFPLNSKSKYYNSEMK
                     DLEFNKDKAIECLAKVEYANVNSVNQNDNKVKNQKKSAKKNSKKLTPEEEAKAKKAEE
                     DRIKKEAEEKKNREKEEVKKSLSEMNLKIIVNRDNSERIKTANIINENLKAIGINSTV
                     NQLSDKDMENALNSKNYDLALVGWKLSIIPDASSIIASSGYTDDKLNGYMSALTSSTS
                     EIETKKAYKDVQTYIKDNATFISLAVRNNYIVSNSRLKGKITPNDFDVYEGISNLDIK
                     SNESN"
     gene            9587..9799
                     /locus_tag="KR294_001996"
     CDS             9587..9799
                     /locus_tag="KR294_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy-metal-associated domain-containing
                     protein"
                     /protein_id="HBH0240075.1"
                     /translation="MKKKLLVEGMSCGHCVNHLKTALTEDIDGIEVLDVDLENKCASV
                     DMKDDVSIEKLKEVIAELGFELKGIE"
     gene            10000..10599
                     /locus_tag="KR294_001997"
     CDS             10000..10599
                     /locus_tag="KR294_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240076.1"
                     /translation="MESRGYKEDLKKMILDMAHKELESYVSQKGAKKYFEGNLDKIIN
                     NNIKKFNQSIGLNRVYLKMLKKCAYQESVTSISRTIKKEALFKSKKELFAFSEYLKLD
                     INKRLSYNQILRKISRYIYYNRSSYAQKYVVFKRGDEEYLLEPEKIKDELISSYRSKT
                     REDMRSIAKLLDIEVEDDYNAEDIRKKVINYIIKEKLKS"
     gene            10827..11198
                     /locus_tag="KR294_001998"
     CDS             10827..11198
                     /locus_tag="KR294_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBH0240077.1"
                     /translation="MKFNFCHNNFNVTNLEKSLDFYKKALGLKEVKRKEAEDGSFILV
                     YLGDGITSHTLELTWLRDWDRPYNLGDNEFHLALEVEEFDEAKKLHKDLDCICFENES
                     MGIYFIADPDNYWIEILPKNH"
     gene            11330..12604
                     /locus_tag="KR294_001999"
     CDS             11330..12604
                     /locus_tag="KR294_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HBH0240078.1"
                     /translation="MKKAIAALGIGAVAVSVSSINASALEKGTVTASALNIRSGPSSD
                     CDKVAKLYKGKTVEILEKSNGWYKVRVSSSVVGWGSAKYISTSGSSEGTSSQNNPTSS
                     GTTISGNGKVNVSSRLNVRSGAGTNYSLVGKANNGDVVKLLEQSNGWYKIKLSNGVTG
                     WASSQYISKTSEDVGTNNSSNSNSTNNSDKKPSSEESIEGKNGKVTSAVSLNVRSGPG
                     TSYSIIGKLNGGDVVELKAKSNGWYKVKLSSGTIGWVSASYISETNEDTKEKPNSSSN
                     QNSQSNSNSKPSFTGNSDKSTAKGSTIVDFAYTLIGIPYQWGASGPDKFDCSGFTQYV
                     FKHSVGVSIPRVSREQANFGSAISMGNYAPGDLVYFDTDGDGTTNHVGIYVGNSKFIH
                     CSGTQTNPNKVKVDNLTSSYWSKVLLGARRFV"
     gene            12715..13659
                     /locus_tag="KR294_002000"
     CDS             12715..13659
                     /locus_tag="KR294_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240079.1"
                     /translation="MNRRKTIYRGFNNNRHKIDLRKYVITIACLCLIGYYSYTKIKDS
                     KILEYVSAKIPFLNNSSDITYKDISDELNSIKKGKKSKSQTNSDDKQETNPEKAVNNT
                     KEPEEVKLATIEGWDMYTIQVAAIDNNDDLKKIQTSLVNNDIPFSVMEKDGVKKIQTY
                     SSFDENDVRKQISSVRKVFPDAFLSHLDAPMLSLEYTSNYAYIESISKELNKLITNFK
                     EESSFWSNAENNVDMEKYNTILTNRKAISQNISKEAEKIDYSEMRLFKDNLIEYVKNV
                     NEKIDTASKAANEEKYSVSKSLLLSSMQEYSMFINSIK"
     gene            13875..15212
                     /gene="rsxC"
                     /locus_tag="KR294_002001"
     CDS             13875..15212
                     /gene="rsxC"
                     /locus_tag="KR294_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxC"
                     /protein_id="HBH0240080.1"
                     /translation="MKLLTFKGGIHPPYRKEYSNTKALEKAQAPKIVYIPLQQHIGAP
                     AKPIVEVGDEVKFGQKIGEQQGFVSCNVHSSVSGKVIAIEQHEVPGGSAQCVVIENDF
                     KEELHESVQPKGQLEDLSKEDIVGIIKEAGIVGMGGATFPNHVKVSPPPDSKAEVVIL
                     NGAECEPYLTADHRLMVENPEDVVFGLRALMKVLDVKKGFIGIETNKPDAIEAIQNVA
                     KDYSEIEVVGLQVKYPQGAEKQLIYACTGKEVPSGGLPIAAGAVVDNVATAAQIAKSI
                     KTGMPLVERITTITGSCIKEPKNLITKVGTLVSEIIEQCGGFKEDKKIGKVIMGGPMM
                     GIAQYTTEIATNKGSSGILCLDEEESRTPDIQNCLRCGRCTDVCPSFLQPLFISAYSL
                     KDDYDTAEYHRAMDCIECGSCSFICPARRPLLQSIRSAKREIGAKRRKQAAQK"
     gene            15235..16212
                     /locus_tag="KR294_002002"
     CDS             15235..16212
                     /locus_tag="KR294_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit D"
                     /protein_id="HBH0240081.1"
                     /translation="MENKLIVSSSPHVRSNEDTSYIMKQVIIALLPAAVAGVYFFRLN
                     ALSAMFFCILGTVGTEFLYQKFTKQKSTIGDFSAVVTGLLLAFNVPASLPWWMCLVGG
                     IFAILVVKMVFGGIGCNFVNPALAARAFLLASFPVAMTAWTQPGVNWIGKNLDAVTTA
                     TPLSFLKNGAAGLADISSNGISLADMMIGNIGGCIGETSAILLLLGGVYLMYKGIINY
                     VIPVFYIATVFILTFLLGGFNITFAIYQLFAGGLMLGGFFMLTDYTTSPMTKKGQIIY
                     AVLAGLITTVIRMYGGYPEGVSYSILLVNCLAPLIDKFVRNRVFGEVAK"
     gene            16212..16781
                     /locus_tag="KR294_002003"
     CDS             16212..16781
                     /locus_tag="KR294_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit G"
                     /protein_id="HBH0240082.1"
                     /translation="MNSMVRLGGTLLAISAIAALALGATNQVTAPVIEQRNIQANNEL
                     RKAVLPEAKEFKEMKEDTYKGLGDGLIAEVYEGLDGSEVVGYTLKAKPSGYGGEIEVM
                     VGISSEGQVTGVDIGNMSETAGLGAKAKDDAFKGQYKGKTAEPLEVAKGSTTADNQIL
                     AISGATITSTAVTTGVNAAIDVFNSALNK"
     gene            16794..17387
                     /locus_tag="KR294_002004"
     CDS             16794..17387
                     /locus_tag="KR294_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit E"
                     /protein_id="HBH0240083.1"
                     /translation="MNLAKVFKNGLIDENPTFVQVIGMCPTLAVTTSAINGIGMGLST
                     AAVLICANLVISLIRKITPDKIRIPIFIVVIATFVTIVGMLLKAYVPALDKALGIYIP
                     LIVVNCLILARAESFAFKTGAMPSIVDGVGQGLGFTVALTIIGAVRELLGNGSLFGMT
                     LFGASFQPVLIFILPPGAFLTLGFLFAGFNKLRSKKA"
     gene            17402..17977
                     /gene="rsxA"
                     /locus_tag="KR294_002005"
     CDS             17402..17977
                     /gene="rsxA"
                     /locus_tag="KR294_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxA"
                     /protein_id="HBH0240084.1"
                     /translation="MNLILLFLSIVLVNNVITSQFLGICPFLGVSKKVDTAVGMGVAV
                     TFVLTLASIITYFIQILLVKTGTGFLQTIAFILVIASIVQFVEMVIQKMSPSLYQALG
                     VYLPLITTNCAVLGIALVNVQKSYNLVETIINGFGAGAGFTLAIVIFAGIRERLELAD
                     IPEAFKGFPITLISAGLMSIAFLGFTGLIKL"
     gene            17993..18964
                     /locus_tag="KR294_002006"
     CDS             17993..18964
                     /locus_tag="KR294_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit B"
                     /protein_id="HBH0240085.1"
                     /translation="MVILTAVLVLGIMGLIFGIVLDFASKKFAVEVDERVEAILGVLP
                     GANCGGCGFPGCGGLANAIVEGNAPVNGCPVGGADVGAKVGEIMGISAEAGEKQVAKV
                     ICKGTCSSAKDKYEYEGISDCRAANVLNSGAKMCKFGCLGLGTCKDACKFDAISIVDG
                     IAVIDEEKCVNCGKCKEVCPKGIIITKPESQEVVVECNSKEFGKAVKEKCTAGCIGCG
                     MCVKACKFDAIIFEDKIAKIDPNKCVGCMQCVAKCPTKVISGDITKKKKVTIDQELCV
                     GCTVCKKQCKFDAIEGELKEKHKVDADKCVGCHLCMEKCPKKAIKIL"
     gene            19184..19768
                     /gene="maf"
                     /locus_tag="KR294_002007"
     CDS             19184..19768
                     /gene="maf"
                     /locus_tag="KR294_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation inhibitor Maf"
                     /protein_id="HBH0240086.1"
                     /translation="MNIILASASPRRKEILENTNVRFDIIKNEIDEIILEGETPKHLV
                     MRLAFEKSMSVASEHNEDVVIGADTVVVLDNAILGKPKDESCARDMLKRLSGREHQVI
                     TGISLINLCEDKKVIDYVISNVKFKTLSEQDIEDYLKTNESFDKAGAYGIQGYGALLV
                     EEIRGDYFNIVGLPISRLGDLLKKYFSINLFYGV"
     gene            19813..20472
                     /gene="radC"
                     /locus_tag="KR294_002008"
     CDS             19813..20472
                     /gene="radC"
                     /locus_tag="KR294_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HBH0240087.1"
                     /translation="MAPEERPREKMLAKGVKSLSNAELLAILLRTGNKNKNAIELANY
                     IINRDIQGIRHLEDMTIEELCNIDGIGLSKSTQIKAALELGSRVASFKPIKYKIRNPW
                     DIQRYYMDSLRYLKKEVFKAVLLNTKNEIISDVDVSIGTLSSSLVHPREVFKEAIRRS
                     ASKIIVMHNHPSGSVEPSREDKNITSRLIKCGEIIGIEIIDHIIIGDGLYFSFKENMI
                     I"
     gene            20593..21603
                     /locus_tag="KR294_002009"
     CDS             20593..21603
                     /locus_tag="KR294_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein"
                     /protein_id="HBH0240088.1"
                     /translation="MTKDMGIDLGTANTLVYIKGQGIVVREPSVVAIRDDSKEVLAVG
                     EEAKKMIGRTPGNIVAIRPMKDGVIADFDITQSMISYFIQKAADKKGVVSPRIAICVP
                     FGVTEVEKRAIEEAARQAGAKDAFLIEEPMAAAIGAGLKVEEPEGNMVVDIGGGTSEI
                     AVISLGGIVTAKSIRIGGDEFDESIVAYVKKEYNLMIGERTAENVKINIGSTFKDDEE
                     INMQIRGRDLISGLPKTIEICSTEVREALKEPVSSIVDAIKSTLERTPPELASDIMEN
                     GIMLTGGGALLRGLDKLITQETGMSVQIAETPLDCVALGTGKSVEDQEIFEKVLMMNT
                     KN"
     gene            21613..22506
                     /gene="mreC"
                     /locus_tag="KR294_002010"
     CDS             21613..22506
                     /gene="mreC"
                     /locus_tag="KR294_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HBH0240089.1"
                     /translation="MALRFDKNKNEKKRINVKVIATGVVAITLIGIVGISIGKFSSGS
                     PVNLGVASDAITSVGKGINDGFSFIKNGFKDVANFKDNSKKVKKLEEENEKLKKNMIA
                     LNAKLDKTESLEELKKTLNFVQEEYKATSISASVVGKNDGNWYESFVIGAGKNSGVKK
                     ESIVMNGSGLVGIVYEVSNNYSKAISLLDSKASVSFKLAKDANAKGTITQNTTLDNKD
                     SYNSKGYLQGYMFDSSYNVIQGDIITTSGLGFFPDGIPIGEVEKVVDDKDKSLKYVVV
                     KPYVDFKNINDVVVIEPRNIG"
     gene            22521..23009
                     /gene="mreD"
                     /locus_tag="KR294_002011"
     CDS             22521..23009
                     /gene="mreD"
                     /locus_tag="KR294_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HBH0240090.1"
                     /translation="MKKVLLCLLGIVLMTIENSITNYIDIFGISFNLVLIYVTIISLY
                     LDELEGGIIAAIIGLIKDITVGGIFGVNALILFIIAYAIGYMRDQLYKGSYIITFVLI
                     FIGSLIDSIVNIGTSSIIYQSYNISTLFVKGLLVAPIVNSLIGLVIYRLSKRAVLKLK
                     ED"
     gene            23021..25999
                     /locus_tag="KR294_002012"
     CDS             23021..25999
                     /locus_tag="KR294_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HBH0240091.1"
                     /translation="MEENKQVDRLKIIKIVMGVIFLAILVKIIYMTTFKYEYYNELAE
                     NKTYKKLAIEAPRGEIKDRYGRLLAGNKNLFTVQVSGNDINKKDANKHSRANEISLKL
                     INLLERNGEEYVDEFPIYVENGKYYYTYDRDIREYKSENGIPNDYNAKESFYYLVDKL
                     ISAGILSQEDKRLDATRLQAKLNENGYYPPILVSKWMFTAERDKRDWLASYKIKETKL
                     SAKEAFEKVRNSDALEIDKSLSDEDARKIMVVRDLIKSKGYSQYNPVTIAKDVGETTI
                     AQIEESAMDLVGVSIAVEPVRYYPNGSLASHMLGYVGKMPSTQIESYLQKGYETGDMV
                     GLAGVEKSNESRLRGTDGYKMVKVDALGRISKEIESKKPKSGDTVYLTLDKDLQEVSD
                     NALKQIIEVASKGGTFKSKFGDKPISAYAGKAQSAALIAIDVKNGEVLASSSYPNYDP
                     NKFAKGISTEDYKALQPKNPNDLLAGSPLLNLVTQGEFQPGSSFKMVTSMAALENGLD
                     PNFTINDPGVIMLGKKSFGDYVWNHGRGNHGMTNLYKAIQESCNIYMATIGTGKTWPD
                     GKSIGIDMNANKILEYAKLFGLDQNTGLQDEVEERAGKVPSTEDKLKSTQALLKSNLE
                     REMANDFVDITREKNPKEYEKRINEIVSWAAEKKTPGRVETMNRLKKLDVKEDRIEEV
                     ADLAVFSYFNFAKWSTADTFNLAIGQGENAYTPAQISRYVAAIANGGNLVELSVVDRA
                     VSSDYSSVKINDQKKVEKIPFKNPDNLKELTKGMKLVARQGTAKSAFADFPIDVAAKT
                     GTAEKSGKIPTDNEYEYLKSHMSSYNVNLNDAIKLADKMKAEKEKELSLAKEKEIKKK
                     LENKDLKDEERKKLEEELEDGVKVRLEDTDKVNSSYLRKAIKELNPKITDDQIDRFKQ
                     DYGSFTWTVAFAPADDPEIAVVCVIPQGDSSVFSLLPTREVIGTYMGLEPTNSKNDNK
                     TNDVNNSSDENINFESQINR"
     gene            26097..26780
                     /locus_tag="KR294_002013"
     CDS             26097..26780
                     /locus_tag="KR294_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum site-determining protein MinC"
                     /protein_id="HBH0240092.1"
                     /translation="MSLREICSQELVEFKGNKRGIIVNIKREAPFEEIQEKIINKLEA
                     YVGFFNGAKISKINSDCLTDMEILELKEGITSRFDVEFVEDQKIEENSNFPTKYVNTL
                     RSGENIEFEGDVVILNDMKPGSKVLSKSNTVVMGDINAGAKVVAGGNVFVMGKIEGFV
                     HAGAEGNEFAYVVAGNLNPKILQIADNIAEAPDDEENYESESEISPEIAFVSNGRIVI
                     ESYLSKLDK"
     gene            26804..27601
                     /gene="minD"
                     /locus_tag="KR294_002014"
     CDS             26804..27601
                     /gene="minD"
                     /locus_tag="KR294_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum site-determining protein MinD"
                     /protein_id="HBH0240093.1"
                     /translation="MSEVIVITSGKGGVGKTTTAANLGTALSLENKKTVVVDADIGLR
                     NLDVVMGLENRIVYDIVDVVEGTCRLKQALIKDKRFDNLYLLPAAQTRDKNAVSVEQM
                     IDLCEKLKESFEYIIIDCPAGIEQGFKNAVAGADRAIVVTNPEISAVRDADRIIGLLE
                     ANEIKEIRLVINRIRNDMVKRGDMMDKQDIIEILAIDLLGLVPDDESIIISTNKGEPA
                     ILDSKSLAGQAYKNIAKRILNEEVPLLDLEVEDGFFGRLKKMFSMAK"
     gene            27619..27903
                     /gene="minE"
                     /locus_tag="KR294_002015"
     CDS             27619..27903
                     /gene="minE"
                     /locus_tag="KR294_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division topological specificity factor
                     MinE"
                     /protein_id="HBH0240094.1"
                     /translation="MLDLFRVFSNEAKTSKSVAKERLKLVLVHDRVDCSPQLLEMIKT
                     DILKVIANYAEIEDDGLEIKMSKCRGEHDDKPVSALVANIPLKNIKDRCM"
     gene            27988..29118
                     /gene="rodA"
                     /locus_tag="KR294_002016"
     CDS             27988..29118
                     /gene="rodA"
                     /locus_tag="KR294_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein RodA"
                     /protein_id="HBH0240095.1"
                     /translation="MKKININYKSTIKLIKQLDWKLIVTVLAIFIFGLVILSSATHAN
                     STGSYNQLIKQGLAFVLGIGMIIVILFFDYNLLGRYYKALYIISLILLAIVLLPGIGT
                     VKGGARSWINLGPLDLQTSEIVKLTFVLSYAKILESKKDKLNTLKEVMPVVVYSLPFI
                     GLLIAQPDLGTGIVFCCMIFAMLFTAGLSSKLIKRGIIILLVSMPLMYLMMADHQKVR
                     IEAFLNPEDVTLKGNYQVMQSLIAIGSGGVTGKGLYNGSQNQEDFLPVQDSDFIFAVV
                     GEELGVIGMAVLIILFMIFLLRLLAIARDAKDFYGTLIVVGVMGMFGYQIIQNIGMTV
                     ALIPVTGVTLPFVSYGGSSLLTSLANLGLVLNVCMRRKKINF"
     gene            29159..29572
                     /locus_tag="KR294_002017"
     CDS             29159..29572
                     /locus_tag="KR294_002017"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HBH0240096.1"
                     /translation="MNIALVAHDQMKNTMVGFCIGYESILKKYGLYATGTTGKRIMDE
                     TELNINRLASGPLGGDQQIGSLIVTQEIDLVIFLRDPLTSQAHETDIQALIRLCDVYH
                     VPIATNLASAEIFIKALDRGELSWREVRKSKSQRI"
BASE COUNT        11814 a         3210 c         5751 g         9122 t
ORIGIN      
        1 ttaagttttt gacatgtaac tatactaata aggaggagta tttatgaatg taaataatca
       61 caagtgccca gagtgtggtg aacatagtaa aaagtttgaa atagtagagg aaaatgagga
      121 ttgtgtaata tttgaatgtt acacttgtgg aactatatct atattaaagt attgtgagaa
      181 ctgtaaagaa tttgtatttg taaatattcc aaataatgtg gagacatatg agtattgttg
      241 tggaaaatgt aataataaaa tttaatataa tataaacata tgtaatttca tatatcattt
      301 ataccaatct catataaaat tcatatataa aatgtattat ataaatatag aaagaactag
      361 cttaaaacat aatataatta ccctaaattt ataatgacaa ctctccctca catcctcaaa
      421 ttatagttgt cattatagaa taacttggct gtttcaaaaa tgtgaaatca ttttagaaac
      481 agcttatttt tttataaaaa taaagaaggc aacgggaagc cttctttcgt gtaaaaaaag
      541 tttaattttt tgttaagatt tgtttgttat tttatattac ctttataata tgtttttatt
      601 tggtggttgg caatggattt tgcacaactg gtcattatta atgtaaaagt ggaatattat
      661 taataaataa taattacaaa attgtaatct ttatttatta aataaatgag taaaataata
      721 tattaatggg tatataatta agacaatact agtttgggga ggataaaatt atggattata
      781 aaacaatcat attaaataga aagtctgtta gagaatataa gaacacagat attaaagaag
      841 aatatcttag tgaaattaag aaatactcag aatcttgtaa gaaactagtt ccagaaatag
      901 atgttgatgt aagaattatg aatagaagtg aagtttttaa taatttagat aaagtagcag
      961 ggtacaaagg aaatatgata gattctccaa gttatattat aatattatct gacataaaag
     1021 ataattacat tgaaaattca gggtacatag gagaaagtat aatctttaaa gtaacagaac
     1081 ttggaattgg ttcttgttgg gttacttttg aagatggaaa aaaggtaaaa gaaaaacttg
     1141 gaattaattc agataaagag gtaacaggaa ttatagctat tggatatgga gaaaatgtaa
     1201 gtaatgctaa agtattaaat gctacaaaaa ctgggcaaaa ttattcaaaa tctgatatgc
     1261 aagttgtaac agataagggg tctactagac taggtgtaga agatgttgtt tatatgaacg
     1321 aatggggaaa tgttgcaagt atagaaatct tagaagaaag agcacttctt gatgcatttc
     1381 actatgcaag attagctcca tctacattaa atagacaacc atggagattt atagttgatg
     1441 gaggcactgt agttttagct gttagaaaag atggtcatac taatttatat gaagaaaaaa
     1501 tagacattgg tatagttatg ctttattttg caacaataat aagtgcaact atgtttgatt
     1561 taaaatggaa tttaggtact ccagacaaag attataaagt gccagaagac tataagatag
     1621 taggatattg taatatataa gatagtgtaa tacttaattt aactacactt aaattaattt
     1681 ttataaaaag ttcaataaca ttttacaata taatgttatt gaactttttt attgtataat
     1741 acaattttta tatttattgt attgattgaa aaatgcttat aaatttaaat gcttacaatt
     1801 ttgtgcatga atagagaggt atattatttt attaaactgt ataatttgct tggaggtaat
     1861 atcaaatgga atggataaat aaattaaatc aagctattac ttatattgaa gaaaatctcg
     1921 aaagtggagt ggattatgca gaagcagcaa aaattgcatg ttgttcaacc tttcattttc
     1981 aaagaatgtt ttcatatatt gcagaagtac cattatctga atatattaga cgaagacgta
     2041 tgactaaggc tgcatttgaa cttcagaaca gtaacatcaa aattttagaa ctatctgaga
     2101 agtatggtta cgattcacca acatctttta atagagcttt tcaaaatata cataacattt
     2161 ctccatctgc agctagagca aagggtgttg ttttaaaagc atatcctaag atgacattaa
     2221 gcatttatgt aaaaggaaat atagaaatgc aatatcgtat tgtagaaaag aaagggtttc
     2281 gtattgttgg tataaaagaa agtatgaaca tgattgtaga agagtgcttt gagaaagttc
     2341 ctaagttgtg ggctaaatgc ataaaaaatg gaacaattga taaactttca gagttaataa
     2401 ataatgaacc ttgtggattg cttggagtta gtgtgtgtac aaatagtaag ggtttagatt
     2461 attatattgc tgctccaaca gataagcctg tattagaaga tactcatgaa tacttaatac
     2521 catcaggcac atgggcagta tttgaatgtg tttctccaat gccaaatgct ctggcaatac
     2581 aggaattgca aaaaagaatt attactgagt ggttaccaag ttctgggtat gtgtatgcta
     2641 atttaccaga tattgaactt tatcccaatg gcgatatcaa tgctcctgat tatactacag
     2701 aagtttggat tccaattcag aaaccaagtt aaaattaata aataatatgg aattaataaa
     2761 taacattaaa attaataaac aacatgaaat tctaaaatta caggctgaaa atagtctgtt
     2821 atttttttgt aaatatggaa agtaagcttt acataaatgg aatatagttg tataattatg
     2881 gaaagtagac tttccgtagt tgagatatta aagggggata gatgtgaaaa atagattaga
     2941 agaaataaga aaagaaagag gcataaaaca agaagaactt gcttctattt tgcaagtatc
     3001 aagacaaact ataggttcat tagaaaatgg taggtataat ccttctatca tcttagcctt
     3061 taagatagct agatactttg atatgagtat tgaagaaata tttatttatg aggaggagta
     3121 aaaatgaaaa agaatatgtt atatgttgga attatatatt ttatttgtgg aattttactt
     3181 gttttattgg ctacatttac tgagttttca tttgaggctt ttatttgggg attatctgga
     3241 gctgctttag gtccaggtgt atgtatgatt cttcaatata tgtattggag taaacctgaa
     3301 agagcagtag attatgaaga aaagataaaa aatcaaagga tagagatgaa tgatgaaaga
     3361 agaattatgt tacgtgataa agctggacgt attactaatc aaatcatgtg ctatgttctt
     3421 gtaattctta tatttattgt ttctatattg agtgtatttt ctgtaatggt aataagcaag
     3481 tgggttttag ttgttcttgg attgcttatt ttatttcaat ttatttgtag tgttgttgta
     3541 tacaataaat tagataaaag gttgtaataa gttatgatat aaaatagaaa attatataaa
     3601 agtaaattag tttttaaatt aatgctagaa gataaattta tataattata taaattttaa
     3661 aaagacacag taatttcaaa aaataactta aaatttaaat caaaaataaa aaaactccta
     3721 atctattgaa taaatagctt taggagtttt taatggtgcc cgaggccgga ctcgaaccgg
     3781 cacggagtat tagtccggtg gattttgagt ccactgcgtc taccaattcc accactcggg
     3841 catgtcatgt atattattat agcaaaaaaa tatattgttt gcaacatatt taattttaat
     3901 atactattat tattatggga atattaaata acactatatt ggtatataat atatatgtta
     3961 caaaaataga taatttttag gagtgatata atttggaaaa aaaattaatt ataatagatg
     4021 gaaattcaat aataaataga gctttttatg ctcttccaga aatgaataat aaagaagggt
     4081 taaagaccaa tgctatatat gggtttacta caatgctatt taaaatgata gatatatata
     4141 aaccaacaca tataagtgta gcttttgaca gaaaagcacc tacatttagg catttagaat
     4201 ataaagatta taaggctgga agaaagggta tgccagatga attggcagaa caattacagc
     4261 cattaaaaga ccttttagat aaatttagaa taaatagact agaaatagat ggttatgagg
     4321 cagatgatat tataggtact gtttctaaaa aagcagaaga aaatggatat aaggtataca
     4381 tagtaactgg agataaagat gctattcaac ttgcttcaga taatacaact acccttataa
     4441 cgaaaaaagg ggttggagaa gtagaagaat acaactttaa ttctgtaatt gaaaaatatg
     4501 agatgactcc aacacaattt atcgatttaa agggtcttat gggagacaag tctgataata
     4561 tacctggagt acctggaata ggtgaaaaaa caggtataaa gcttataaaa gagttttcta
     4621 gtatagagaa tctaatagag aatacagata agcttaaagg tagtgtaaaa aagaaaatag
     4681 aggaaaacaa agaaatagct attcaaagta aaagacttgc aacaattata agagatgtgc
     4741 caatagaagt ggatttagat agtatgattt ttggcgatta tgataaagat gaacttttag
     4801 ataaatttag atactttgga tttacaagtc tcttatcaag attagttgat ttggtcgatt
     4861 cagatgacac agaacacgta gaagaaaaaa tagaaatatt aaaattaaaa gatatagaaa
     4921 aatttataga tgaagtaaac aaaaaaggac aagttatttt aaaaactgtt agaggacaag
     4981 gtaatatact tgaaaaaaat ataatatata tttttataag tgtagatgga gaaaaaatat
     5041 attatgtaga ttcaaatgaa gtgtcaaagt tagatagtat attttcaaat aatgaaatta
     5101 aaaagtatgg atataattta aaagatgatt atatatcttt aaaaccatat aatataaact
     5161 tagaaaatat gtattttgat ataacaatag ctgagtactt aatagattca acttcatcta
     5221 cctcatatga ttgtagtgca atagctatga agtatttatc aaaaaaggtt aaatcaaaag
     5281 aagaattatt aggaaagggt gttaaatcta aaaactatga ggatttagaa tttgaggatt
     5341 tagcagagta tatgggtcaa ataatatgca cagttaaaga aacagttcct atgatggaaa
     5401 gaagtctaat ggatatgagt atggatggtc ttttttatca tgtagagatg cctttagtag
     5461 aagtcttagg tcatatggag tatgaaggta taaaagtaga caaaagtata ttggatgaat
     5521 tgagtgttga atttaaagaa ataatagcta cattagaaaa ggaaatttat gaattatcag
     5581 gagagccatt caatataaat tcaccaaaac aattgggtgt tatattattt gaaaaattag
     5641 agcttccaat aattaaaaaa actaaaactg gatattcaac taatgcagat gttttagaaa
     5701 aattaagaga taagcatcca ataatagata agataactga gtatagacaa atagtaaagt
     5761 taaattctac ttacgttgaa ggacttttaa atataataaa tccagaaagt aatagaatac
     5821 attcatcatt taatcaaact ataacgacta caggaagaat ttcatctaca gaaccaaatc
     5881 ttcaaaatat acctataaaa atggaaatgg gtagaaaaat aagaaaagtg tttattgcag
     5941 atgataactg taagttggtt gatgccgatt actcacaagt agagctaaga gttcttgcac
     6001 atatgagtca ggatgaaaat atgatagaag catttaaaca tcatgaagat attcatacca
     6061 aaacagcttc acaagttttt aatgttccta tggaagatgt tactagtgaa ttgagaggtg
     6121 cagctaaagc tgtaaacttt ggtattatat atggtaaaag tgactttggt ctagctgatg
     6181 atttaaatat acctgttcca aaggcgaaag aatatatcga aagttatttt gctaaatacc
     6241 ataaaataaa agagtttatg gacacaacag tagaaaaggc tagtgaggat ggatatgctg
     6301 taacaatttt aaacagaaga agatatatac cagaaataaa gtcaagcaat tttatggaaa
     6361 gaaatagagg aaagagattt gcaatgaatg caccaataca aggaagtgca gcagatataa
     6421 taaaaattgc tatgataaat gttcataaaa aattggaaga gaacaatttg aaatcaaaac
     6481 ttatactaca agttcacgac gagttgatag ttgaagcaat tgatgatgaa atagatatag
     6541 ttaagaaaat agtaaaagaa gaaatggaaa atgctgtaaa tatggatgtt cacttagatg
     6601 tagatttaaa tgtaggtagt tcttggtatg agacaaagta ggtgatttta tgttgatatt
     6661 aggacttaca ggaggaatag gctgtggaaa aagcagccta tcaaatatat ttagaaatct
     6721 taacattcct atagtggatg ctgatattat atccaggaag atatttgagg ataagttgtt
     6781 attggaaaaa gtatttgtcc attttgggca aagtataaaa aatgatgatg gaactctaaa
     6841 tagaaaagct cttgggaaaa tagtttttag tgatgaagaa aaacttaagg aattaaataa
     6901 cttgactcat ccacgaataa gagaaaaaat aataagtgaa atagaaaaat tgagaaaaaa
     6961 aggcgaaaat atagtagtgt tagatgcggc aatattggta gaaagtggtt ttttagatat
     7021 ggttgacaag ctattagtag ttacttgtaa acaagaagta caaattagta gaatacaaaa
     7081 gagagataat tgcagtgagc aggaagcact tagtaggata aattcacaga tgagtcagga
     7141 agaaaaatcc aaatatggtg attatataat agataattcg ggaacaataa ctgaattaga
     7201 aagtaaagca cataaattta ttgagtacat gaaggagaat tggcgtgaat agtaagaaag
     7261 tattgattct atctattttt ataatcttat ttggggcact attaatggaa agcaaagtaa
     7321 tacataaatt tttatatcct aaaaaatatt cagagtatgt agaaaagtat tcgaaagaat
     7381 ttaatttaga tgaaaatata gtttacagtg ttattaaagc cgaaagtaag tttaatagtt
     7441 ctgctgtttc aaaaaaggaa gcaaaaggat taatgcaaat attagacata actagagatt
     7501 ggggagcaga ggaactaaat ttaaaaaatg tggatatttt cgacccagag actaatataa
     7561 gacttggctg ttggtattta agtaagttat acaaagaatt tggtaaatta gatttagtga
     7621 tagctgcata taatggtggt tcaggtaatg tgaaaaaatg gttagaaaat aatgaatata
     7681 gtaaagatgg cgaaaatcta catgatatac cttttaagca aacttcaaaa tatgtagaaa
     7741 aagtaaaaaa taattacgaa cattataata agatatatgg caagaaagga aaaaactaat
     7801 gaagagaata aaagtcttaa cagtcgtttt agctataact cttatggtag ctggttgtag
     7861 taatactaaa acaaaacaaa gtagtagtga ttcaagttta caaagtcaaa gttctataga
     7921 tgctaagtat ataaacttaa caatggtaac tccaaaaact ataaatccta taactaatac
     7981 tgataagtct gttggttata taatgaattt agtttatgat agtttattta ctatagatga
     8041 gaactacaat gtaattcctc aattagttaa ggagtataat atagctcagg atggaatgag
     8101 tatagatata aagctaaaag atgcaaagtg gcatgatgga aaaaatatta cttcaaatga
     8161 tgtaaactat actattggtt taattcaaaa aagtgcagat agtccatata atgaatttac
     8221 taaaaatata gcttctgtga atattaaatc agataaagat tttacaataa aatttaaagc
     8281 tagatatgct ttttcaattg atagtttaat ttttccaatt gtatctcaaa atcatttaga
     8341 ttcaaaagat gtaaatgaca agaataataa tatgatagga aatgggaaat ataaaataga
     8401 atcatataca gaaagagaag gaatggtttt atctgtaaac aaagattact atgaagaagt
     8461 tccaaaaacc atgaagaaca taaaagtagg tatggtgcct aatgaagatg caaggacatc
     8521 tatggttatg gctcttgata gtgatataac caatgttaca ttaaatgatt taagtaagtt
     8581 tcaagaaaaa gagtttaata taacaaaata tcaaggaaga gattatgagt gtgtattatt
     8641 taattataat aatccttttt tcaaagatgt taattttaga aaagcaattg cacactctat
     8701 agataaagat agaattatta gtgaaggtta tatggatgat gctactccag ttaattttcc
     8761 acttaattca aaatcaaaat actataatag tgaaatgaag gatttagagt ttaataaaga
     8821 taaggcgata gagtgtcttg ctaaggtaga atatgcaaat gtaaactcag taaatcaaaa
     8881 tgacaataaa gtaaaaaatc agaaaaaatc agctaaaaag aactcaaaga agcttacgcc
     8941 agaagaagaa gcaaaagcta aaaaagcaga agaagataga atcaaaaaag aagctgaaga
     9001 gaaaaaaaat agagaaaaag aggaagtaaa gaaaagtctt tctgaaatga acttaaagat
     9061 aatagtaaac agagataata gtgagagaat aaaaactgca aacataataa atgaaaactt
     9121 aaaagctata ggaataaata gtacagtaaa tcagctgtca gataaggata tggaaaatgc
     9181 tcttaattct aaaaattatg atttagcatt agttggatgg aaactatcaa ttataccaga
     9241 tgcaagtagt attatagcga gtagtggata tactgatgat aagttaaatg gatatatgtc
     9301 tgcacttaca agttctacgt ctgaaattga aacaaaaaaa gcatacaaag atgtacagac
     9361 atatataaaa gataatgcaa catttataag tttagctgtg agaaacaact atattgtaag
     9421 taatagtaga ttaaaaggta aaattactcc aaatgatttt gatgtatatg agggaatatc
     9481 taatttagat ataaaatcga atgaatcaaa ttaaatgatt aatttctatt taaaaagtat
     9541 aaactatatg atagaatacc cttatagggt ataaggaggt aattaaatga agaagaaact
     9601 attagtagaa ggtatgagtt gtggtcattg tgtaaaccat cttaaaactg cattaacaga
     9661 agatatagat ggtattgaag ttttagatgt agatttagaa aataagtgtg catctgtaga
     9721 tatgaaagat gatgtatcta ttgaaaaatt aaaagaagtg atagcagaat taggatttga
     9781 actaaaggga attgaataga aattgataaa ctaaaaaaag acctctattg ggggagtaat
     9841 agaggtctaa aaatggggga gattgagtat gtttgatttt acattactat tatctcccct
     9901 tttaaattaa tatatacata aaaagtaaaa aaattttgta atgactcaca tttcttgagc
     9961 tttttgaata tactataaat agctaaggga gggagtatca tggaatctag gggatataaa
    10021 gaggatttaa aaaaaatgat acttgatatg gcccacaaag aacttgagag ttatgtatca
    10081 caaaaaggag caaaaaaata ctttgaaggt aacttggata agattattaa taataatata
    10141 aaaaaattca atcaaagtat tggtcttaat agagtatatt taaaaatgtt aaaaaagtgt
    10201 gcatatcaag aaagtgtaac ttcaatatca agaactataa agaaagaagc attatttaaa
    10261 tcaaaaaaag agctatttgc tttttcagag tacttaaaac ttgatattaa caagcgactt
    10321 tcatataatc aaattttaag aaaaatatca agatatatat actacaatag aagttcatat
    10381 gctcaaaaat acgttgtttt caaaagagga gatgaagaat atcttttaga accagagaaa
    10441 ataaaagatg aattaatatc aagctatagg tcaaagacta gagaagatat gaggtcaata
    10501 gcaaaacttt tggatataga agtagaagat gattataatg ctgaagatat tagaaaaaaa
    10561 gtaataaatt atattattaa agaaaaactt aaaagttaga gttttaaaga ataagttctg
    10621 ccaatttgca tgattaagta taacttgggt ataaattttt tatgcatttg aaagagctta
    10681 ttcttttttt gacatattct tttaaataat ttaccatgat ttggtaattg gtcatcatca
    10741 ttcaaatttt taacttaata tgatttaaat aaatttataa taatgatata atataaaaaa
    10801 aataaaaatt ggagagtgat ttcaaaatga agtttaattt ttgtcataac aatttcaatg
    10861 ttactaattt agaaaaaagt ttagattttt ataaaaaagc tttagggctt aaagaggtaa
    10921 agcgcaagga agcagaagat ggaagtttta tattagttta tttaggagat ggcattacta
    10981 gtcatacatt agaattaact tggcttagag attgggatag accatataat ttaggagaca
    11041 atgaatttca tctggcttta gaagttgagg agtttgatga ggcaaaaaaa cttcataaag
    11101 atttagattg catatgtttt gaaaatgaaa gtatgggaat ttattttata gcggacccag
    11161 ataattattg gattgaaata cttcctaaaa atcactaatt ttaaggatat gtttataatt
    11221 tctttacaat taataagaaa ataagttatc attaaattgt agggactaaa aatggataat
    11281 aatgttatga atttatgact ataaaaattt gttgggggga gtgatagtag tgaaaaaagc
    11341 tatagcagct ttaggaattg gggcagtagc agtatctgtt agctccataa atgcaagtgc
    11401 tcttgaaaag ggaacagtaa cagcaagtgc cttgaatata agaagtggac caagttctga
    11461 ttgcgataag gtagcaaaat tatacaaggg aaaaactgta gagattttag aaaagtctaa
    11521 tggatggtat aaagtaaggg tatcgagttc tgttgttgga tggggaagtg caaaatacat
    11581 atcaacaagt ggttcgtctg aaggtacatc aagtcaaaat aatccaactt caagtgggac
    11641 aactattagt ggaaatggta aagtaaatgt gagttctaga ctgaatgtaa gaagtggtgc
    11701 aggtactaac tattcattag ttggtaaagc aaataatgga gatgtagtaa agttactaga
    11761 acaaagcaat ggatggtata aaataaaact atcaaatgga gttactggat gggctagtag
    11821 ccaatatatt tctaaaacat cagaagatgt tggaacgaac aattctagta attcaaatag
    11881 tactaataat tctgataaaa aaccatctag cgaagaatca attgaaggca agaatggtaa
    11941 ggtaacatct gctgtgagtt taaatgtaag aagtggtcct gggacaagct attctataat
    12001 aggaaaatta aatggtggag atgttgttga attaaaagct aaaagtaatg gttggtataa
    12061 ggtaaagtta tcgagtggaa caattggatg ggtgagtgcc agttatattt ctgagactaa
    12121 tgaggataca aaagaaaaac caaattcatc atctaaccaa aattctcaat ctaatagtaa
    12181 ctcaaagcca tcatttactg gaaattcaga taaatctaca gcaaaaggtt caacaatcgt
    12241 agattttgca tatactctta ttggaatacc atatcaatgg ggagcttcag gacctgataa
    12301 atttgactgt tctggattta cacagtatgt ttttaaacat tctgtaggcg tttctattcc
    12361 tagagtttct agagaacagg ctaattttgg aagtgcaatt tctatgggaa attatgcacc
    12421 aggagattta gtttattttg acactgatgg tgatggaaca actaatcatg taggtatata
    12481 cgtaggaaat agtaaattta tccattgtag tggtactcag actaatccta ataaggttaa
    12541 agtggataat ttaactagtt catattggtc taaagtatta cttggtgcaa gaagatttgt
    12601 ttagtaagta caatttctta ttaaaaaatt agaagaaata attatttata ttcataaatt
    12661 gtgactctta aaaatatact ttattaataa tataattttg ggagggacaa actaatgaat
    12721 agaagaaaaa cgatatacag aggatttaat aataatagac ataagattga tttacgtaaa
    12781 tatgttataa cgattgcttg cttgtgtcta attggctatt attcttatac aaaaataaaa
    12841 gatagcaaga tattggagta tgtatcggct aaaataccat ttctaaataa ttcatcagat
    12901 ataacttata aagatatatc tgatgaatta aattcaataa aaaaagggaa aaaatctaaa
    12961 tcacaaacca attcagatga taaacaagaa actaatccag aaaaagcggt aaataacact
    13021 aaagagccag aagaagtcaa attagctact atagaaggct gggatatgta tactattcaa
    13081 gttgctgcaa tagataataa tgatgatttg aaaaaaatac agacatcatt agttaataat
    13141 gacatacctt tttcagttat ggagaaggat ggagtaaaaa aaatacagac ctattcctct
    13201 tttgatgaaa atgatgttag aaagcagata agcagtgtaa gaaaggtgtt tccagatgca
    13261 tttttatcac acttagatgc acctatgttg tctttagagt atacaagtaa ctacgcttat
    13321 atagagagta tatctaaaga attaaataaa ttaataacaa actttaaaga agaatcaagt
    13381 ttttggtcga atgctgaaaa taatgtagat atggaaaaat ataatactat tttgacaaat
    13441 agaaaggcaa tatcacaaaa tatatcaaaa gaagctgaaa agattgatta ttctgaaatg
    13501 cgtttattta aagataattt aatagagtat gtaaagaatg tgaatgaaaa aattgataca
    13561 gcttcaaaag cagcaaatga agaaaaatat agtgtaagta aaagtctgct tttatcatcc
    13621 atgcaggagt actctatgtt tataaattct ataaaataaa atacagaaaa tttggacttt
    13681 agaaagctat atgaaaagga ttgtttaatt aagcaatcct tttcctcaat ttgacttaat
    13741 atagaggtgt tgatttataa aataaattat aaaaatacgg atattttttt aacaattgtt
    13801 aagatttttt aatatatata gtatacttat agaaggcaga aaaaatgttt ttttatagat
    13861 aagggggtaa aacaatgaaa ctcttaactt ttaagggagg gatacatcct ccatatagaa
    13921 aagagtactc taacacaaag gcacttgaaa aagctcaagc tccaaagata gtttacattc
    13981 ctcttcagca acatataggg gcaccagcta aacctattgt tgaagttggt gatgaagtaa
    14041 agtttgggca aaaaataggt gaacaacaag gttttgtttc atgtaacgtt cattcttcag
    14101 tatcaggtaa agttattgct attgaacaac atgaagtacc aggaggttca gctcaatgtg
    14161 tagttatcga aaatgacttt aaggaagaat tacatgagag tgttcaacca aaaggtcagt
    14221 tagaggattt gagcaaagaa gatatagtag gtatcataaa agaggcagga atagtaggta
    14281 tgggtggagc tacattccct aaccatgtaa aagtatctcc tccaccagat agcaaggcag
    14341 aagtagttat attaaatggt gcagaatgtg aaccatactt aactgcagac cacagattaa
    14401 tggttgaaaa tccagaagat gttgtgtttg gtttaagagc attaatgaag gtattagatg
    14461 tcaaaaaagg atttatagga attgaaacga ataaaccaga tgctatagaa gcaattcaaa
    14521 atgtagctaa agactatagc gaaatcgaag ttgttggcct tcaagtgaaa tatccacaag
    14581 gagcagagaa acaacttatt tatgcgtgta caggcaaaga agttccatct ggtggattac
    14641 caatagcagc aggtgcagtt gttgacaacg ttgccacagc agcacagata gctaagtcta
    14701 ttaaaacagg tatgcctttg gttgaaagaa tcactacaat aacaggtagt tgcatcaaag
    14761 agccaaagaa cctaataaca aaagttggaa cattagtttc agaaataata gaacaatgtg
    14821 gtggatttaa agaagataag aagattggta aggttataat gggtggacct atgatgggaa
    14881 tagctcaata tactactgaa atagcgacta acaaaggttc ttcaggaatt ttatgtttgg
    14941 atgaggaaga atcacgtact ccagatattc aaaactgttt aagatgtgga agatgtacag
    15001 atgtatgtcc atcattctta caaccacttt tcataagtgc atattcttta aaagatgact
    15061 atgacacagc tgaatatcat agagcaatgg attgtataga atgtgggtct tgctcattta
    15121 tttgtccagc aagaagacca ttacttcaat ctataagatc agcaaagaga gaaataggag
    15181 caaagagaag aaagcaagct gctcagaaat aaagaaagtt aagggggaaa aacgatggaa
    15241 aataagttga tagtatcatc ttctcctcat gtgagaagta atgaagatac ttcatatata
    15301 atgaaacaag ttattatagc actccttcca gcagcagtag caggagtata cttctttaga
    15361 cttaatgctt tgagtgctat gtttttttgt atacttggta cagtaggtac tgaattttta
    15421 tatcaaaaat ttacgaagca aaaaagtact ataggagatt tttcagctgt tgtaacagga
    15481 ttattattag catttaacgt accagcatca cttccttggt ggatgtgtct agtaggagga
    15541 atatttgcaa tattagtagt taaaatggta tttggtggaa ttggatgtaa ctttgtcaat
    15601 ccagcacttg ctgcaagagc atttttatta gcatcattcc cagtagcaat gactgcttgg
    15661 actcaaccag gtgttaactg gataggtaaa aatttagatg cagttactac agcaactcca
    15721 ttaagctttt tgaaaaatgg agcagcagga ctggcagata tttctagcaa tggaattagt
    15781 cttgctgaca tgatgatagg gaatattggt ggatgtatag gtgagacatc agcaatatta
    15841 ttattattag gtggagtata cctaatgtat aaaggcataa taaattatgt tataccagta
    15901 ttttacatag caactgtatt tatattaaca ttccttttag gtggatttaa tataactttc
    15961 gcaatatatc aactgtttgc tggaggactt atgttaggtg gattcttcat gcttacggat
    16021 tatacaactt cgcctatgac taaaaaaggt caaataatat acgctgtatt agctggtctt
    16081 ataacaactg ttataagaat gtatggtgga tatccagaag gtgtatctta ctcaatacta
    16141 ttagtgaact gtcttgctcc acttatagat aagtttgtta gaaatagagt atttggggag
    16201 gtggctaaat aatgaacagt atggtgagat taggtggtac tttacttgct ataagtgcaa
    16261 tagctgcatt agctcttgga gctactaatc aggttacagc tccagtaata gaacaaagaa
    16321 atatacaagc aaataatgaa cttagaaaag cagtccttcc agaagcaaaa gaatttaaag
    16381 aaatgaagga agatacttac aaaggccttg gagatggtct tatagctgaa gtgtatgaag
    16441 gtttagatgg ttctgaagtg gttggatata ctttaaaagc taaaccaagt ggatatggtg
    16501 gagaaattga agttatggta ggtatatcat ctgaaggtca agttacaggt gttgacattg
    16561 gtaatatgtc agaaacagca ggtcttggag caaaagctaa ggatgatgca tttaagggtc
    16621 aatacaaagg aaaaactgct gagcctcttg aagtagcaaa aggaagtaca acagcagata
    16681 atcaaatatt agcaatatca ggtgcaacta ttacatctac agcagttact acaggagtaa
    16741 atgctgctat agatgttttc aatagtgctc ttaataaata aggagggtta attatgaatt
    16801 tagctaaagt atttaaaaat gggctaatag atgagaaccc aacatttgtt caagttatag
    16861 gtatgtgtcc aacactagcc gttacaactt cagcaataaa tggaattggt atgggtcttt
    16921 caacagcagc agttttaata tgtgcaaatt tagttatatc tttaataaga aaaattacac
    16981 cagataagat aagaatacct atatttatag tagttatagc tacatttgtt acaatagtag
    17041 gtatgctttt aaaagcatat gttcctgctc ttgataaggc tcttggtata tatataccat
    17101 taatagttgt taactgttta atattagctc gtgcagaaag ttttgctttc aaaacaggag
    17161 ctatgccttc aatagttgat ggtgtaggtc aaggtcttgg atttactgtt gcacttacaa
    17221 taataggtgc agtaagagaa ttacttggaa atggtagttt atttggaatg acattatttg
    17281 gagcatcttt ccaaccagta ttaatattta tattaccacc aggtgcattc ttaacattag
    17341 gattcttatt tgcaggattt aataaattaa gaagtaaaaa agcatagtgg aggtgtaata
    17401 aatgaattta atacttttat ttttaagtat cgttcttgtt aataacgtta taacatctca
    17461 attcttgggt atatgtcctt tcttgggagt ttctaagaag gttgatacag cagtagggat
    17521 gggagttgca gttacgttcg ttttaactct agcttcaatt ataacttatt ttatacagat
    17581 tttattagta aaaactggaa ctggattctt acaaacaata gcttttatat tggttatagc
    17641 ttctatagtt cagttcgttg aaatggtaat tcaaaagatg agtccatctt tatatcaagc
    17701 attaggagtt tatttacctc ttataactac aaactgtgca gttcttggta tagctctagt
    17761 taatgttcaa aaaagttata atttagtaga aacaataata aacggatttg gagccggagc
    17821 tggatttact ttagcaatag taatattcgc aggtataaga gaaagactag aattagctga
    17881 tataccagaa gcatttaaag gtttccctat aacgcttata tcagcaggtt taatgtcaat
    17941 agctttctta ggatttacag gacttataaa gctataaaaa agaggggtga aaatggtgat
    18001 acttacagct gtattagttt taggaattat gggcttaatc ttcgggatag tactagattt
    18061 tgcatctaaa aagtttgctg tagaagtaga cgagagagtg gaagctatac taggagtact
    18121 tccaggagcc aactgtggag gttgtggatt tccaggttgt ggaggtcttg caaatgcgat
    18181 agttgaaggc aatgcaccag ttaatggttg ccctgtaggt ggagcagatg ttggtgcaaa
    18241 agttggagaa ataatgggaa taagtgctga agcaggtgag aaacaagtag caaaagttat
    18301 ttgtaaagga acttgttcaa gtgcaaaaga taaatatgag tatgaaggaa tatcagattg
    18361 tagagcagca aatgttttaa actcaggtgc taagatgtgt aaatttggat gtttaggtct
    18421 tggaacatgt aaagatgctt gtaaatttga tgctatttct atagttgatg gaatagcagt
    18481 aatagatgaa gaaaagtgtg taaattgtgg aaaatgtaaa gaagtttgtc ctaagggtat
    18541 aataatcaca aaaccagaaa gtcaagaagt agttgtagag tgtaatagca aagagtttgg
    18601 taaagctgtt aaagaaaaat gtactgctgg atgtattggc tgtggaatgt gtgtaaaagc
    18661 ttgtaaattt gatgcaataa tatttgaaga caaaatagct aagatagacc ctaataagtg
    18721 tgtaggttgt atgcaatgtg tagcaaaatg ccctacaaaa gtaatatcag gtgacataac
    18781 taagaaaaag aaagttacta ttgaccaaga actttgtgtt ggatgtacag tgtgcaaaaa
    18841 acaatgtaag tttgatgcaa tagagggaga attaaaagaa aaacataagg tagatgcaga
    18901 taaatgtgta ggatgccatt tatgtatgga aaaatgtcca aagaaagcta ttaaaatttt
    18961 gtaatatgga caaaataagg atatggaata atttccatat ctctaatgag tacataaaac
    19021 agaggtatgg aataatttcc atacctctat tttatgtata tttattctaa tggtaataaa
    19081 tataacaata gtgtaacaaa aaaggttcga catttctgtt gaatttttta caatatagtg
    19141 atagactaaa taggtacaaa ttacgtacaa atgaggtgaa taaatgaata taatcttggc
    19201 atcagcctct ccaagaagga aagaaattct agagaatacg aatgtaagat ttgatataat
    19261 taaaaatgaa attgatgaga ttatattgga aggtgaaaca ccaaaacatt tagttatgag
    19321 attagctttt gaaaaaagta tgtctgtagc atctgaacat aatgaagatg ttgttattgg
    19381 agctgataca gttgttgttt tagacaatgc tattttagga aaaccaaaag atgagtcttg
    19441 tgcaagagat atgttaaaaa gactatctgg aagagagcat caagtcataa caggtattag
    19501 cttaataaac ttgtgcgaag ataaaaaggt aattgactat gtaatcagca atgtgaaatt
    19561 taaaacgtta tcagagcagg atattgagga ttatctgaaa actaatgagt catttgacaa
    19621 agcaggagcc tatggtatac agggttatgg agctttgtta gttgaagaaa ttagaggaga
    19681 ttattttaat atagttggtc ttccaatttc aaggttaggc gacctattaa aaaaatattt
    19741 tagtataaat cttttttatg gagtgtgatt tatctgaaaa agtcatttaa ttcaaccatt
    19801 aaggtaaaag aaatggcacc agaggaaaga cccagagaaa agatgcttgc caaaggcgta
    19861 aaaagcttat caaatgctga gttgttggct atacttttaa gaactggcaa caagaataaa
    19921 aatgctattg aattagccaa ctatataata aatagagata ttcagggtat tagacattta
    19981 gaagatatga caatagagga gctgtgtaat atagatggaa ttgggttatc aaaatcaacc
    20041 caaattaaag cagctttaga actaggctct agagtagcta gttttaaacc tataaagtat
    20101 aaaataagga atccttggga tatacagagg tattatatgg atagcctaag gtatttaaaa
    20161 aaagaggttt ttaaagcggt tcttttaaac acaaaaaatg agataatatc tgatgtagat
    20221 gtatctatag ggactttaag ctcgtcatta gtccatccaa gagaggtttt taaagaagct
    20281 ataagaagaa gtgcaagtaa gataatagtg atgcataatc acccttcagg aagtgtagaa
    20341 ccatcaagag aagataaaaa tatcacatca agacttatta aatgtggaga aataattgga
    20401 atagaaataa tagaccatat aattattgga gatggattat actttagctt taaagaaaat
    20461 atgataattt gactttatat gtgataaaat aataggagaa tgttttaaac atgattctta
    20521 atagtaggaa ggagtaaaat catggctaag gaaaaaaaga aagaaaaaaa aggttttttt
    20581 agttttaata agatgacaaa ggatatggga atagatttag ggactgcaaa tacattagtt
    20641 tacataaaag gacaaggtat tgttgttaga gaaccatcag ttgtcgcaat aagagatgat
    20701 agtaaagagg tattagcagt aggtgaagaa gccaaaaaaa tgatagggag aacaccagga
    20761 aatatagtag ctataagacc tatgaaagat ggagtaatag ctgattttga cataactcaa
    20821 tcaatgatta gctattttat acaaaaagcg gctgataaaa aaggtgttgt aagtccaaga
    20881 atagctatat gtgttccttt tggagttaca gaagtagaaa agagagctat agaagaggct
    20941 gcaagacaag caggagctaa agatgcattc cttatagaag agccaatggc agcggctata
    21001 ggggctggat taaaagttga agaaccagaa ggtaatatgg tagttgatat tggtggaggt
    21061 acttcagaaa tagctgtaat atctttagga ggaatcgtta ctgctaaatc tataagaata
    21121 ggtggagacg aatttgacga gtctatagtg gcttatgtaa aaaaagaata taatcttatg
    21181 ataggtgaaa gaactgctga aaatgtaaaa attaacatag gttctacatt taaagatgat
    21241 gaagaaataa atatgcaaat aagaggtaga gatttaatct caggattacc taaaacaata
    21301 gaaatatgct ctacagaagt tagagaagca ttaaaagaac ctgtaagttc aatagtagat
    21361 gcaataaaat ctacactaga aagaactcca ccagaattag cctcagatat aatggaaaac
    21421 ggaataatgc taacaggagg aggcgctttg cttagaggtc ttgataagct tattacacag
    21481 gaaactggta tgtctgtaca aatagcagaa acacctcttg attgtgttgc acttggaaca
    21541 ggtaaatctg ttgaagacca agaaatcttt gaaaaagtat taatgatgaa tactaagaat
    21601 tagaagttgg tgatggcctt gagatttgac aagaacaaaa atgagaaaaa aaggattaat
    21661 gttaaagtga tagcaacggg cgtagttgct atcactttaa ttggaattgt gggtatatca
    21721 attggtaaat tttctagtgg tagtccagta aatttaggag tagcttcaga tgctattaca
    21781 agtgtaggta agggaataaa tgatggattt tcttttatca aaaatggttt taaagatgta
    21841 gcaaatttta aagataattc taaaaaggta aaaaaattag aagaagaaaa tgaaaaactt
    21901 aaaaaaaata tgatagcttt aaatgccaaa ctagataaaa cagaatcgct agaagagtta
    21961 aaaaagacac tgaactttgt acaagaagag tataaggcga caagtatttc agcaagtgtt
    22021 gttggtaaaa atgatggaaa ctggtatgag agttttgtca taggtgcagg aaaaaattca
    22081 ggtgtaaaaa aagaaagtat agttatgaat ggtagtggat tagttggcat agtttatgag
    22141 gtttccaaca attatagtaa ggcaatttca ctattggatt ctaaggcatc tgtaagcttt
    22201 aaactagcaa aggatgccaa tgctaaaggt acaattactc aaaatactac tttagataat
    22261 aaagatagtt ataatagtaa aggatatttg caaggatata tgtttgactc atcatataat
    22321 gtaattcaag gagatataat aacaacatca ggtcttggat tcttcccaga tggtatacca
    22381 attggcgaag ttgaaaaagt ggttgatgat aaagataagt cattaaaata tgtagttgta
    22441 aaaccttatg ttgattttaa gaatataaat gacgttgtag tcatagaacc aagaaatata
    22501 ggataaaggg gataaaaaca atgaaaaaag ttttactttg tctgttgggg attgtgctta
    22561 tgactataga aaatagtata acaaattata tagatatttt tggcataagc tttaatttag
    22621 ttcttatata tgtaaccata atctctcttt atttagatga attagaaggt gggattatag
    22681 cagcaataat agggcttatt aaagacataa ccgttggtgg aatttttggt gtaaatgcat
    22741 taattttgtt tattattgca tatgcaattg gatacatgag agatcagcta tataaaggta
    22801 gttatattat tactttcgtt ttaattttta taggcagttt aattgattca attgtcaata
    22861 taggtacatc tagtataatt tatcaaagct acaacatatc aacacttttt gtaaaaggtc
    22921 tactagtagc accaatagtg aatagtttaa ttggtttagt aatatatcgc ttatctaaaa
    22981 gagcagtttt aaaacttaaa gaagattagt tggtgatttc atggaagaaa ataaacaagt
    23041 tgatagacta aaaataatta agatagtcat gggcgtgata tttttagcta ttttagtaaa
    23101 aataatctat atgactacat ttaaatatga atattacaat gagttagctg agaataaaac
    23161 atataaaaag ttggcaatag aagctccaag aggagaaata aaagatagat atggaagact
    23221 gttggcagga aataaaaact tatttactgt tcaagtttca ggtaacgata ttaataagaa
    23281 agatgcaaat aagcattcaa gagcaaatga aatatcatta aaacttataa atttgctgga
    23341 gagaaatggt gaagaatatg tagatgagtt tcctatatat gtagaaaatg gaaagtacta
    23401 ttatacatat gacagagata ttagggaata taaatcagaa aatggtattc caaatgatta
    23461 taatgctaag gaaagttttt attacttggt ggacaaactt atatcagctg gaatattatc
    23521 tcaagaagat aaaagattgg atgcgacaag attacaggca aaactaaatg aaaatggata
    23581 ttatccacct attttagtta gtaaatggat gttcacagca gaaagagata agagagattg
    23641 gttggctagt tataagataa aagaaactaa actgagtgcc aaagaagcgt ttgaaaaagt
    23701 aagaaatagt gatgcattag aaattgataa aagtttgagt gatgaagatg caagaaaaat
    23761 aatggtcgta agggatttga taaaatcaaa aggatattct caatataatc cagtaactat
    23821 tgctaaggat gtgggagaaa ctacgattgc tcaaattgaa gaaagtgcta tggaccttgt
    23881 tggtgtttca atagcagtag aaccagtaag atattatcct aatgggtcat tagcttctca
    23941 tatgttagga tatgtaggaa aaatgccatc cactcaaata gaatcatacc ttcaaaaagg
    24001 ttatgaaact ggagatatgg taggtcttgc aggagtagaa aagagtaatg aaagtagatt
    24061 aagaggaact gatggttata aaatggttaa agttgatgca ttgggtagaa tcagtaaaga
    24121 aattgaatct aaaaaaccta aatcaggaga tactgtgtat cttacactag ataaagattt
    24181 acaagaagtt tcagataatg cattaaaaca gataatcgaa gttgcttcta aaggaggtac
    24241 ttttaaaagt aaatttgggg acaaaccaat tagtgcatat gcaggaaaag cacagtcagc
    24301 agctcttata gctattgatg ttaaaaatgg agaagtatta gcttcatcaa gttatcctaa
    24361 ttatgaccca aataaatttg caaaaggtat ttctacagag gattataaag cacttcaacc
    24421 aaaaaatcca aatgacttac tagcaggaag tccactttta aacttggtta cacaagggga
    24481 atttcagcca ggttcttcat ttaagatggt aacttcaatg gcagcgttag aaaatggtct
    24541 ggatccaaac tttactataa atgaccctgg ggttataatg ttaggtaaaa aatcttttgg
    24601 tgactatgta tggaaccatg gtagaggaaa ccatggtatg acaaacttat ataaagcaat
    24661 acaagagtct tgtaatatat atatggcaac aattggtaca ggtaaaacat ggccagatgg
    24721 aaaaagcatt ggtatagata tgaatgcaaa taaaatactt gagtatgcaa aattatttgg
    24781 gcttgaccaa aatacagggc ttcaagatga agtagaagaa agagcaggta aagttcctag
    24841 cacagaagat aaattgaaat caacacaagc tcttctaaag tcaaatttag aaagagaaat
    24901 ggcaaatgat tttgttgata taactagaga aaaaaatcct aaagaatatg agaaaagaat
    24961 caatgagatt gtaagctggg cagcagaaaa gaaaactcct ggtagagttg aaacaatgaa
    25021 taggctaaaa aaattggatg ttaaagaaga tagaattgaa gaagtagcag atttagcagt
    25081 atttagttat tttaattttg caaaatggag tactgcagat acattcaact tagctatagg
    25141 acaaggtgaa aatgcttata caccagctca aatatcaaga tatgtagctg ctatagcaaa
    25201 tggaggtaat ttagtagaat tatctgtagt tgatagagct gtttcaagtg attattcatc
    25261 agttaaaatt aatgaccaga agaaagtcga aaaaatacct tttaaaaatc cagataactt
    25321 aaaagaatta acaaaaggta tgaaattggt tgcaagacaa ggtacagcga agagtgcttt
    25381 tgctgatttt ccaatagatg tagcagcaaa aactggtaca gctgagaaaa gtgggaaaat
    25441 acctacagat aacgagtatg aatatttaaa aagtcatatg tcatcttata atgtcaacct
    25501 aaatgatgcg attaaactag ctgataagat gaaagcagaa aaagaaaaag agctttcatt
    25561 agctaaggaa aaggaaataa aaaagaaatt agaaaataaa gatttgaaag acgaagaaag
    25621 aaagaaatta gaggaagaat tagaagatgg agtaaaagtt agattagagg acactgataa
    25681 ggtgaattct tcatatctaa gaaaagctat aaaagaatta aatccaaaaa taacagatga
    25741 ccaaatagat agatttaaac aagattatgg ttcttttacg tggactgttg cttttgctcc
    25801 agcagatgac ccagaaatag ctgttgtatg tgtaattcct caaggtgatt caagtgtatt
    25861 ctcactttta ccaactagag aagttattgg aacttatatg ggattagagc caactaatag
    25921 taaaaatgac aacaagacga atgatgttaa caattcttct gacgaaaata taaatttcga
    25981 gtcacaaatt aatagatagc tcaatctatg tataaacttt agctttatat agaaaaaata
    26041 aaagggttta aagcgtattt gaagaatata aatgatatat cactctggag gttgttatgt
    26101 ctttaagaga aatttgtagt caagaactag tagagttcaa gggtaataaa agagggataa
    26161 tagtaaatat aaaaagagaa gctccatttg aggaaataca ggaaaaaata ataaacaaat
    26221 tggaagcata tgttggcttt tttaatgggg ctaaaattag taaaattaat agtgattgtt
    26281 taactgacat ggagattcta gaacttaaag aaggaattac ttctagattt gatgtggaat
    26341 ttgttgaaga tcaaaaaatt gaagaaaata gtaattttcc aacaaaatat gtcaataccc
    26401 taagatctgg tgaaaatatt gaatttgaag gtgatgtagt tatattgaat gatatgaaac
    26461 ctggttcaaa agtcctttca aaatcaaata cagttgttat gggagatata aatgctggtg
    26521 ctaaggttgt agcaggaggt aatgtttttg taatgggtaa aatagaaggt tttgtacatg
    26581 caggtgcaga aggcaatgaa tttgcatatg ttgttgctgg aaatcttaat cctaaaatat
    26641 tacaaatagc agataatatt gcagaagctc cagatgatga agaaaattat gaaagtgaat
    26701 cagaaattag cccagaaata gcctttgtaa gtaatggaag aattgtaatc gaaagctatt
    26761 tgtcaaagtt agacaaatag aaagaaaaat agggggtagt attatgagcg aagttatagt
    26821 tataacatct ggtaaaggtg gggttggaaa aactactacc gcagcaaact taggaactgc
    26881 gctaagccta gaaaataaaa aaacagtagt tgtggatgca gatattggac ttagaaactt
    26941 agatgtagta atgggtcttg aaaatcgaat agtttatgac atagtagatg tagttgaagg
    27001 aacttgtagg cttaagcaag ctctaataaa agacaaaaga tttgataatc tatatttatt
    27061 accagcagca caaactagag ataaaaatgc tgtctcagtt gagcagatga ttgacctgtg
    27121 tgagaaacta aaagaatctt tcgagtatat aataatagat tgtccagcag gtattgagca
    27181 aggctttaaa aatgcagtag ctggggcaga tagagctatt gtagttacta atccagaaat
    27241 atcagcagta agagatgctg atagaataat aggtctatta gaagcaaatg aaataaaaga
    27301 gataagatta gttataaata gaattagaaa tgatatggtt aagcgtggag acatgatgga
    27361 taaacaagat ataatagaaa tattagcaat agatttgtta ggtcttgttc ctgatgatga
    27421 aagcataatt atatcaacaa ataaaggaga gccagctata cttgattcta agtcacttgc
    27481 tggtcaagca tacaaaaata tcgcaaaaag gatactaaat gaagaagttc ctctacttga
    27541 tcttgaagtt gaagatggat tctttggtag acttaaaaaa atgtttagca tggctaagta
    27601 gcaaaggagg atacatctgt gttagattta tttagagttt tttctaacga ggctaaaact
    27661 agtaaatctg ttgctaaaga gaggttaaag ctagttttag ttcatgatag agtagattgt
    27721 tcaccacaac ttttagagat gataaaaaca gacattttaa aagtaatagc taattatgca
    27781 gaaatagaag atgatggtct tgaaataaaa atgtctaaat gcagaggtga gcatgatgac
    27841 aaacctgtat ctgcattagt tgctaatata ccactaaaga atataaaaga tagatgtatg
    27901 taattagtgc ttaaaagggg gatatcctta ttggtatatg ccccttttat ttaattatat
    27961 gtttaaagat agaaagacgg tgattctttg aaaaaaatca atattaatta taagtcgaca
    28021 attaagttga taaaacagtt agactggaaa cttatagtta cagtattagc tatctttatt
    28081 tttgggcttg ttatacttag tagtgcaaca catgctaatt caacaggttc atataatcaa
    28141 ttgattaaac aaggattagc ttttgtactt gggataggaa tgattatagt catattattt
    28201 tttgactata accttctagg caggtattat aaagcgcttt atataataag tcttattttg
    28261 ttagccatag ttttattacc tggaattggg acagtaaaag gtggagctag gtcgtggatt
    28321 aacttaggac cacttgactt gcagacatct gaaatagtca aattaacatt tgtactaagt
    28381 tatgcaaaga tacttgaatc caaaaaggat aaattaaata cgttaaagga agttatgcct
    28441 gttgtagttt attctcttcc atttatcgga ttattgattg cacaaccaga cttgggaaca
    28501 ggaattgtat tttgttgtat gatatttgca atgctgttca cagcaggtct tagctcaaag
    28561 ttgataaaaa gaggaataat catactatta gtgtcaatgc cactgatgta tttaatgatg
    28621 gcagaccatc aaaaggtaag aatagaagct tttctaaatc cagaagatgt aactctaaaa
    28681 ggaaactatc aagttatgca atctctgatt gcaattggtt ctggaggcgt aactggtaaa
    28741 ggactttaca atggaagtca aaatcaagaa gattttttac ctgtacaaga tagtgatttt
    28801 atatttgctg ttgtaggtga agaacttggt gtaataggaa tggcagtgtt gataatctta
    28861 tttatgatat tcctattaag gcttttagca attgcaagag atgcaaaaga tttttatgga
    28921 accctcatag tggttggtgt tatgggaatg tttggttacc agataatcca aaatataggt
    28981 atgacggttg cgttaatacc agtaactgga gtaacattac cttttgtaag ttatggagga
    29041 agttcgttat tgacatcttt agcaaactta ggattagtac taaatgtgtg tatgagaaga
    29101 aagaaaataa atttctaaat ttaaatacat ctaaacataa attgaggaga ttagatatat
    29161 gaatatagca ttagtagcac atgaccaaat gaaaaacact atggtcggat tttgtatagg
    29221 ttatgaatca attttaaaaa agtatggact atatgcaact ggaactacag gaaaaagaat
    29281 aatggatgaa actgaattaa atataaatag attagcatct ggtcctttag gtggagacca
    29341 acaaataggt tctttaatag taacacaaga aatagattta gttatttttt taagagaccc
    29401 attgacatct caggctcatg aaacagatat acaagcgtta ataagacttt gtgatgttta
    29461 tcatgttcca atagctacaa atctagcttc agcagaaata tttataaaag ctcttgatag
    29521 aggagaacta tcatggagag aagttagaaa aagcaaaagt caacgtattt aaaaaatatt
    29581 aatattacag tctaaagaaa cagatatata agtgtttaat gccctagtct ttctgttgga
    29641 ataaatctag tacctgtaga aatcttatga aagatttaaa tgatgaagag ctaaatttga
    29701 gattaaataa ttaggaaata gattatagat agagtagtag aatttaaact attactctat
    29761 tttaataata tgaaatagaa tcaagtctat tattatatat atttaaactt ataggtaata
    29821 ctatttcaac caagtaaatg ttgttatgac aacattaata aaacaaaaat ttatttttaa
    29881 aatttgataa atagctg
//
LOCUS       DAEPKC010000045        29577 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.045, whole genome shotgun sequence.
ACCESSION   DAEPKC010000045 DAEPKC010000000
VERSION     DAEPKC010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 29577)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29577)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29577
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.045"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..727
                     /locus_tag="KR294_002018"
     CDS             <1..727
                     /locus_tag="KR294_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH0240097.1"
                     /translation="LIRMYEVIQENRNSIAIEKADLQELVSDISHQIKTPIANLKMIN
                     TTLLNQTFKTEIQKDFLMDMENQLDKLDFLMQSMVKTSRLETGIITLSKKKNSIYETI
                     ATALSGILFDAEKKNIEVTVDCDPNLYIIHDKKWTSEAIFNILDNAVKYTSSNGKIRV
                     ATECWVMYTKIDIIDNGKGISESRQAEIFKRFYREEDVHDIEGIGIGLYLSRKIISLQ
                     GGYIKVTSDIGKGSTFSIFLPNK"
     gene            809..1474
                     /locus_tag="KR294_002019"
     CDS             809..1474
                     /locus_tag="KR294_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0240098.1"
                     /translation="MSILQVINLKKYYGQSSNITKALDGVTLSIEKGEFISIVGTSGS
                     GKSTLLNMMGGLDNPTSGKVIIKGKELSTMSDEQLTIFRRRNIGFIFQNYNLVPLLNV
                     YENIILPIGLDGETIDKDFINEIINMLSLEEKLYDIPSNLSGGQQQRVAIARALVTKP
                     AIILADEPTGNLDSRTSSDVLSLLKVTSKKFNQTIVMITHNNEIAQLTDRIIRIEDGK
                     IVN"
     gene            1487..3904
                     /locus_tag="KR294_002020"
     CDS             1487..3904
                     /locus_tag="KR294_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0240099.1"
                     /translation="MFRNNNRTFIRKIALNDLKINKLKTYLSGIIIMISTCLLLTVTL
                     VSYNASVDLVNASPYHAIYKSVDEKAKNILYKNKNFSGVGTYKLIGSNKKTDCIMSIV
                     YADDTAIKLMNFQPLKGKLPTNKNEIAISEKYLQEFGLDKDIGDSIKLNYYDDITNKE
                     VQCDFIIVGFLENYYQDNAKQYYTVVSNDYFKNIASTPLQNKSNTFDESRPDTVDVLV
                     KLSEENTEKDSASIKTQLNKIGLSLGIKKYNIYLNDNYIESNLIDGEQIITVLVVGIV
                     VLFSSVFVIYSIFYISVVNSVQMYAKLKSLGMTSFQLKKIISLQGNILSIIFIPLGVI
                     ASCIIAYIIQPLAWQMIADLFIILILSLVMFLTVRISLFKPARIISKISAIEAMQYTE
                     TKFRKKAKNFSYINIKNLALKNIESNRKKNLIALISLSISGVLFISIANLANSIDFKK
                     QLSQQFVYNEDYIISIKSDNLYEHITEIQQNNPLTDSLKNEIKSIHGVKKLIESKSIK
                     SNIIEPYIKDRDEKQFITLIKGITPELSKSLEEYIVSGKIDYTHLDSDSLIINKYRTK
                     YYGLNLKVGDTVTFNIFSGNDIIKKKMKIIGIIDNSNTGGMFFASDKTLESLTPYNTN
                     LDFSILIDKKHSKEVEEKLLSIIQKNSNLMLYSYEDDYRMITRAFQYIIIASYIFVGL
                     ISCFGILNMTNTLINSVLIRKKEFALLQAVGMTRKQLRNMLYREGLNISIKAICTSST
                     LGYFGSNLLCTFIKDVIRLDFINFKFSIFTILIFSFVLIGIQVLVTELLVRNIEKKSL
                     TERLRSQ"
     gene            complement(4085..4876)
                     /locus_tag="KR294_002021"
     CDS             complement(4085..4876)
                     /locus_tag="KR294_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBH0240100.1"
                     /translation="METKQYLIDFYNTYDEDSRLALKHGMVEFLTTMHYIDKYIKSGD
                     CVLEIGAATGRYSHTLARQGYDVDAVELVEHNIEVFHKNTQSNENISITQGNAMDLSV
                     FPDNKYDITLLLGPLYHLYNKEDKQQALHEAIRVTKPGGVVFAAYVISDGCLIDEGFH
                     RGNINVSEYIEKGLIDPQTFAAKSEPKDLFELVRKENIDDLMSAFNVTRLHYVASDGL
                     ALYMREAVDSMDDDAFALYLKYHLATCEREDLVGVTSHAIDIFRK"
     gene            complement(4909..5496)
                     /locus_tag="KR294_002022"
     CDS             complement(4909..5496)
                     /locus_tag="KR294_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH0240101.1"
                     /translation="MPPKVKITKEMILNTVLDITREVGFEAVNARSIASKLQCSTRPI
                     FTCYENMNELKNEFLAFAYEYYNQYVVNYSNSKSVSPYLLLPLSYIEFAQEETHLFKL
                     LFINDLDLMMEEANDFYKEIDNEKKARLFSESIGIELECAKVIFLDLFLYTHGIAVLT
                     ATKKLTLDRYSAEKMLKNILTAFIRQEKPDWNLSI"
     gene            complement(5673..7064)
                     /locus_tag="KR294_002023"
     CDS             complement(5673..7064)
                     /locus_tag="KR294_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="benzoate/H(+) symporter BenE family transporter"
                     /protein_id="HBH0240102.1"
                     /translation="MERLARREQPHIKFGMFKIRIPFIHYRFEKPEAIQGIISSMTSL
                     GTIGLSTQILGLPYEVAWSMAIINSILYCLHVFMGDPVVPGWITASITLTTAYLLKFS
                     MGIERIQALTALQIDLGIIFILMGITGVAGKLVSKIPNSIKGGILMGVGISTIISEFN
                     PKGRFDSYPISITVGILVACFVMFSERFDTLKVKNKFLFHLGEYGVVSAILVSLIVGI
                     FSKEIEIPRFSFDNLVYIVDFKNLINTVSPFGIGFPSVMLFIQGIPMAFMIYIIAFGD
                     FITGENLVLSESENRKDEYIDFNSNRSNVISGIRNIFMAIFSPYIPMCGPLAATLTGS
                     VAQRYKVGKEAMQSVFSGMGTLVWVSAIFICFYPIAQIATPLIPLALSVTLLVQGYLC
                     TKLSMELCNTGVEKGLIGLMGGVIAAKGGTWGLAVGFILYFILIDSKKRKEKDINSIE
                     DCVYEILDKKKSI"
     gene            complement(7254..8552)
                     /locus_tag="KR294_002024"
     CDS             complement(7254..8552)
                     /locus_tag="KR294_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase/BAAT N-terminal
                     domain-containing protein"
                     /protein_id="HBH0240103.1"
                     /translation="MKVNVYNVESFVDERLKIMVSDLIPNTKLKISVKMEFPWCKGEE
                     FSSYGVFCSNEKGEVDLDLVEPIEGTYKADNCMGLIYSLEKSKTEGKNFAENISIDKP
                     IIMNMIFETSIERKEVELKRIFKSEDITTKYISDEFIGKLFYKQNSNNKTILMLGGSD
                     GNLDALDLLAAPLASRGFNVLTVAYFALEGLPDKLEEVPLEYFEKVFEWISENEITST
                     KEIFVHGTSKGGELAFLLASRYEQIKKVVVSQPHIYCFQALNGLMSGNDTSSWSYKGE
                     PFPYIKVDNDIFFEEQKKNISKDIPFGFNSTYKKSLKRAENRKEARIKIENSKADILM
                     IAGKEDNIWNSYEACLEALEIFEENNYPYNVELLTYNNMGYPLPIPYIMPLKETLCMS
                     MSRGIFSSGGTVEGNSKGQFESWNRTIEFYKKPLSSDLNN"
     gene            complement(8909..9784)
                     /locus_tag="KR294_002025"
     CDS             complement(8909..9784)
                     /locus_tag="KR294_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase"
                     /protein_id="HBH0240104.1"
                     /translation="MITFDVNGAIIRFDDTKNNYNKIRKIFKLYALEISKNFERDCLN
                     SFQNLKQISDRGLSLGEKYIEESFKKGIETIVSFGIITIDIDTFKSVYCEKYLDFKRL
                     FNNLNKTFIIPNKNKKNGHASFLEIESTIKKMSNYLYNDCFKIHYAVVDALIENRITA
                     VHSYIDEESIKKSNALFNNYKDGFIGKADECKVVKQIITLNPYREDVYEFLVKEDGDF
                     SKEIERLTEFLGYDIREYKASLMDIYINELMESDENDVENAKEKIEKYARYIGCSDEN
                     LYVARVNAIYTFANA"
     gene            complement(9977..10663)
                     /locus_tag="KR294_002026"
     CDS             complement(9977..10663)
                     /locus_tag="KR294_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HBH0240105.1"
                     /translation="MFGVIANSLAIAGGCIVGLIIKGGLPQRVSDTIMNGIALCVLYI
                     GISGALEGKNTLVTIISVAVGALIGELIDIDKWVNKLGAFLQSKFSKGNKKDSIAEGF
                     ISSSLLFCIGAMAVVGSLESGLTGSHDTLFVKSVIDGIASIIFTASLGIGVMFSAISV
                     FLYEGIICVGASFLNGFLSDPVVTEMTAAGSLLIIGLGLNVLKLTNIKVANLLPAIFI
                     PILFGVFGII"
     gene            complement(10712..11245)
                     /locus_tag="KR294_002027"
     CDS             complement(10712..11245)
                     /locus_tag="KR294_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HBH0240106.1"
                     /translation="MSDLNNKKEQDENESSMNETKIYDILDKLNVEYDVVEHEAVYTA
                     EQLVILDGITKGCQCKNLFLRNAKGNKYYLIVVKGEKQVDLNSLKDKIGSSRLSFASP
                     ERLYNVLKLLPGSVNPFSLINDTERKVELYIDKDVIKEDYLNFHPNINTKTVNISRKG
                     FEEFLEYLKYPIQSIDV"
     gene            complement(11289..11921)
                     /locus_tag="KR294_002028"
     CDS             complement(11289..11921)
                     /locus_tag="KR294_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclase family protein"
                     /protein_id="HBH0240107.1"
                     /translation="MKVFDLTHVTHNDMPVYAEPNRPDIKKVAIIEENGYQETLISVF
                     SHNGTHMDSPRHMYTKGETLDKLDIENFVGKAYVLELEKGNENIELEYLKKYEDEIKN
                     SDFIIFKSGWSKFWDKKQYYVGYPTLTKEAANYIANTNIKGIGIDMLSVDRYDTSVFE
                     VHHILFEKGKIIIENLTNLENVPEKFLFIAAPFKYNDADGAPVRAIAIVE"
     gene            complement(12011..13090)
                     /locus_tag="KR294_002029"
     CDS             complement(12011..13090)
                     /locus_tag="KR294_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HBH0240108.1"
                     /translation="MKIAIFLGAGASAAENLPIQNELFSEYFKKLNPTNYNTKMNREL
                     YIFFKQMFNIDIVKDNIDNANFPTFEEVLGLLDLAEQRKEAFRNFGLENLNNRSDSIR
                     FLRQYLILLMAEAIHNTPRTDNKYHKLLVENLLENDLLLDTTFISANYDIHIDNTVTG
                     LRDKNDLPIMLDYGVEFTNFKEELNWRKPKEPLIKLYKIHGSLNWLYCPICNSVTLTP
                     HEGGVMKLIENSSETKCLECGELTEPIIVPPTYFKNMSNIFLSNVWNETEKTLRDTDL
                     LIFCGYSFPEADMHIKYMLKRVQTNRKKPPLKIMVFNNHSQKQRITLKKEEGRYKRFL
                     GEDVIFTDNSFQDFSVNPLRFIKNI"
     gene            complement(13223..14569)
                     /gene="pepV"
                     /locus_tag="KR294_002030"
     CDS             complement(13223..14569)
                     /gene="pepV"
                     /locus_tag="KR294_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HBH0240109.1"
                     /translation="MKEQIKEKVNSLQDEMISSIQESVKIPSVISEATENCPFGENVD
                     KALRGILDLCKSLGFKTVYKDGYYGYAEIGQGEKMIGILGHVDVVPEGDLESWNYPPF
                     EAVLEDGKLYGRGTQDDKGPTISAIYAVKALMDLNVDFNKRIRFIFGADEENLWRCIN
                     KYKENNEEIPNYGFTPDSRFPITNAEKGLLQVHLTCDSKSDIELSVGKALNAVPGKAI
                     YIGKYSDKLKKELDKLNFEYTVEGNKICIIGKSVHSAASDTGINAVARLCIALNNIGI
                     DSNIIKFLAEVIGEDANGNNIIPNCKDDVSGKLTVNIGRVTIDNEKEFAGIDVRIPVT
                     YKKDDFVKELKKMTDKYNLNYEEYDFLDSIYVPEDTLLVKTLRKVYEEETGLDGTPLS
                     SGGATYARALDNCVAFGAIFPGKPETEHQANEYLIVEDIIKATQIYALSIYELLKI"
     gene            complement(14638..15918)
                     /locus_tag="KR294_002031"
     CDS             complement(14638..15918)
                     /locus_tag="KR294_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine gamma-lyase family protein"
                     /protein_id="HBH0240110.1"
                     /translation="MLNETKELLKDYYGIDDDTFKLSQEIMEEIKDKFEEIKEIREYN
                     QYKVLKAMQESKLSDMHFNWTTGYGYNDIGREKIEEIYSKVFNTEDALVRPIIVNGTH
                     ALTLCIQGIVRPGDEILSVTGRPYDTLEGVIGIREEKGSLKEYGVTYDDVDFLEDGNL
                     DLEGIKNKINDRTKLVMIQRSKGYSWRKSLSISDIKEAIEVIKSVKPEAIVMVDNCYG
                     EFLDTKEPTDVGADVMAGSLIKNPGGGLALTGGYIAGRKDLIELISYRMTSPGIGKEC
                     GLTFGTTRNVLQGFFLAPYIVSQAVMGAIFCSRAFEKLGYDVLPKYDDLRSDIIQCIR
                     LNNADEVISFCEGIQEAAPVDSYVKPVPWDMPGYESEVIMAAGAFIQGSSIELSADAP
                     IRPPYNVYFQGGLTFDHSKMGTLKAIEFIKKLKK"
     gene            complement(16045..16305)
                     /gene="hfq"
                     /locus_tag="KR294_002032"
     CDS             complement(16045..16305)
                     /gene="hfq"
                     /locus_tag="KR294_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA chaperone Hfq"
                     /protein_id="HBH0240111.1"
                     /translation="MKNTVLNLQDLFLNNARKERIPVTIYLVNGVQVKGLVKGFDSYI
                     ILIEGDNRQQNMIYKHAVSTIQPGKYINLTNQNQNNNNNNNR"
     gene            complement(16419..17354)
                     /gene="miaA"
                     /locus_tag="KR294_002033"
     CDS             complement(16419..17354)
                     /gene="miaA"
                     /locus_tag="KR294_002033"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HBH0240112.1"
                     /translation="MKKIPLIILTGPTAVGKTDLSIKLAKDMNAEIISADSMQIYEYM
                     DIGSAKVTEEEMQGVKHYLIDEVKPDYPFSVSEFQQRAKKYIHEINEKEKCVLVTGGT
                     GLYLNSLIYNMDFAQSDANNELREELQKQLAEKGIDYMHNKLKELDEESANRIHKNNT
                     KRVIRALEVCLSGKKMNDFSSDLKFNEEYQPIIIVLNRDREHLYQRINMRVDIMIKNG
                     LVEEAKKLLSMGFKKDMISMQGIGYKEILKYLDGEYTYEEAIEIIKRDSRRYAKRQIT
                     WFKRYKTAKWFDLDQYENIDELKNEIILYIKDSIK"
     gene            complement(17392..19359)
                     /gene="mutL"
                     /locus_tag="KR294_002034"
     CDS             complement(17392..19359)
                     /gene="mutL"
                     /locus_tag="KR294_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HBH0240113.1"
                     /translation="MKNIINILDDLTINKIAAGEVVERPSSVVKELIENSIDAGANKI
                     SIDIIDGGKSLIKITDNGIGIPSSEVEKSFLRHATSKIKKIDDLYDLYSLGFRGEALA
                     SISAVSKLEMTTKTKDEIIGTKIYVEGGKIISKEPIGSTNGTTIIIKDIFFNTPARQK
                     FLKSTHAETINISDLINKLAIGNPNIQFKYTNNNKQMLNTPGDGKLVNTIRSIYGKEI
                     TENIIDVEFKCNHFKMNGYIGNNNIYRSNKNLQHIYINKRFVKSKIIIDAITESYKSI
                     IPIGKHAVCFLNIEVDPSCIDVNIHPNKLEIKFEKEQEVYIELRDFLKVKLIHSNLIG
                     KYATYSDKKTQPRIAINSREKSTDYKLRNNDLLESTPKNSNITKGKDEVIEVVTLSSE
                     KPINEFQSVSEVLNASVEDDVKNINYLSEDSANDNIQEEFQVDGIKNEGNYYLGDSIK
                     DSEEEYLCSSKRKFSLYGYFVIGVVFNTYIILSKDDSMYLLDQHAAHERILYERYMEK
                     FYRQDINMQILLDPVVIEVSNIDMLQIENNLELFMKFGFELEIFGNNHIMVRCVPTIF
                     GVPETEKFILQIIDNIEEITSNYDLKGERFASMACRSAIKANDKIYDIEIKSLLEQLE
                     KCENPFTCPHGRPIMVEISKTEIEKMFKRIM"
     gene            complement(19370..22213)
                     /gene="mutS"
                     /locus_tag="KR294_002035"
     CDS             complement(19370..22213)
                     /gene="mutS"
                     /locus_tag="KR294_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HBH0240114.1"
                     /translation="MQIDMNKLTPMMKQYLEVKNRYKDCILFFRLGDFYEMFFEDALV
                     ASKALEIALTGKACGLEERAPMCGVPFHSANSYISKLVENGYKVAIGEQMEDPSTAKG
                     IVRREVIRVITPGTVLDGNLLENKKNNYLLSLYKDGTNIGLTYVDISTGETNATCLNE
                     DKVIEEIAKIHPTEIIINDLDFIEKLRDIATVSNIYINESFSDNYLDINILKEYFPDV
                     YLQKLKFDDKGLIKSSLSILLNYIYNTQKQITSNINNINIYNSSEYMVLDMFTRTNLE
                     LTQTIRGNKKKGSLLHVLDKTSTAMGGRLLRKYVEEPLINKSKIENRLDVIEEIKDDF
                     ILREDLNDILKNIYDIERICGKIAFERVTPKELIHLKNSIEKLPNLKDTINLSNAKIL
                     KEYVSEMDKLDDIYNLIDEAILEEPTITIKDGNIIKSDFSDELKELREISKNGAFLVK
                     EIENREREKTGVKSLKIGFNKVFGYYIEITKANFKQAKLDETYIRKQTLSNAERYITP
                     ELKEIEEKILHAEEKIKSLEYEIFVEIRDTIYKNIDRIQKVAKTIANIDVFVSLATVA
                     HINNYVKPAINENNKLDIRNGRHPVVENIVGEENFVPNDTYLNRGENIINIITGPNMS
                     GKSTYMRQTAIIALMAHIGSFVPAESADIPILDRIFTRVGASDDLSQGQSTFMVEMNE
                     VSLILKNATERSLVILDEIGRGTSTYDGISLAWSIVEYIQKNIRCKTLFATHYHELTD
                     LEEEFKEVKNYSIAVKEDGEGIIFLRKIIPQGADKSYGIYVAKLAKLPDEVIERAKYI
                     LKDLEKNHVYNSVAINGDKENNNIINSNLDEELVKVNQSNFKNKYESLKIEHELIVKD
                     YKHIKKDYDKLNSKFKALNDEVALMKQNDDKEKINQEDSVKEVALTQISFDSVNRDIL
                     SEEILNLDILNMTPLDAINSLYNLQRKAKEIKS"
     gene            complement(22374..23108)
                     /locus_tag="KR294_002036"
     CDS             complement(22374..23108)
                     /locus_tag="KR294_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0240115.1"
                     /translation="MLTQMNFYHNKKVKVSIENVSKTYKDIEVLKDISIDVYEGEFVS
                     ILGPSGCGKSTIFNIITKLTDYDSGKVNINGKYSYMYQKDLLLPYKTIIDNVSLPLIL
                     KKEKKSKARSMVKPYFEVFGLSGYEDKYPSELSGGMRQRANFLRTFINSNDIMLLDEP
                     FGALDSLTKTSMQKWLLDVKKKVNSTILLITHDIDEAIMLSNRIYVISKKPSIVKKEF
                     VIDSRKLNEDNLENIIKLKKEIISLL"
     gene            complement(23077..24090)
                     /locus_tag="KR294_002037"
     CDS             complement(23077..24090)
                     /locus_tag="KR294_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBH0240116.1"
                     /translation="MNFKKLGILGLVSVFTLATITGCSSNNNKDKNNDKDTSSKKVTM
                     VLDWTPNTNHTGLFVALDKGYYKEEGLDVEIVQPPESGAETLVATGKADFGISYQEQV
                     TYAKTSEDPLPIKAVATVIQHNTSGFASPKEKNITTAKDFEGKTYGGWGSPSEEAVFK
                     AVMKKNGADFNKLKIVNTGQDDFFAAMKTVDFAWIFEGWDAVKADLIGYDLNFIPVKD
                     LDERLDYYTPLIISNETVLKNNPELAKKFLKATTKGYEYAIKNPEESAKILVKHAPEV
                     DEKLALKSQEYLASKYKDDAPRWGEMKDSVWNNYTSFLKEYKLIDKDMKASDAYTNEF
                     LPQ"
     gene            complement(24112..24882)
                     /locus_tag="KR294_002038"
     CDS             complement(24112..24882)
                     /locus_tag="KR294_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0240117.1"
                     /translation="MKNLEIIDKVKDSIYPIATFLFILILWQSMVGVLEVPQYILPTP
                     VDIINVFFKDYQNLSIHAVVTIGEAILGFIVAIIISLVIGILMDFVSIIKKCLYPIML
                     VTQMIPTIIIAPLFMIWFGFGTMPKVLMVMLTCFFPILISFVDGIENIDKDYLNLFKT
                     MDSNKVNTFIHLKFPMAMDKFFSGLKISATYAVMAATVAEWLGGTKGLGVYMLRSKSA
                     YALDKVFASTILVVIFSLMFVGIVQAVKKVVIRHRLID"
     gene            complement(24857..25147)
                     /locus_tag="KR294_002039"
     CDS             complement(24857..25147)
                     /locus_tag="KR294_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MTH1187 family thiamine-binding protein"
                     /protein_id="HBH0240118.1"
                     /translation="MVIADIAVMPLRPYKGEEEMYKVVDACIAEIEKSGLKCEIGAMS
                     TTVEGDFDEVFELLKKVHKIPFNLGCERVITVARVDEKAGGLTIDEKLRNHR"
     regulatory      complement(25278..25377)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     regulatory      25997..26086
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            26139..26315
                     /locus_tag="KR294_002040"
     CDS             26139..26315
                     /locus_tag="KR294_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240119.1"
                     /translation="MFMDKMDRCTHILTAYICSSRDYCNFIDTQLNDFILEYGENVVE
                     SCLHQVMVLVSRYN"
     gene            complement(26430..26786)
                     /locus_tag="KR294_002041"
     CDS             complement(26430..26786)
                     /locus_tag="KR294_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0240120.1"
                     /translation="MDIDNNFEEFPNIEERQKDFNCSIGFTMTVIGSKWRAIILWHIL
                     KQEPIRYSQLKKEVVHISHKILSQELKYLERDGLIKRISYPTIPPKVEYLSTKRGKSL
                     ESILLELCNWGKQYMR"
     gene            27042..27955
                     /locus_tag="KR294_002042"
                     /pseudo
     CDS             27042..27955
                     /locus_tag="KR294_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007061260.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family isomerase"
     gene            28186..28797
                     /locus_tag="KR294_002043"
     CDS             28186..28797
                     /locus_tag="KR294_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA pyrophosphatase"
                     /protein_id="HBH0240121.1"
                     /translation="MINDIKNKFKNYKPYINGYKNMKRASVLIPIVEINNTHYILFEV
                     RSKNLKHQPSEISFPGGKIESGETPYEAVIRETCEELGTFSDNIEVISSLDLLITPVK
                     FIIHPYLGYIKNINNLNINKDEVDHTFLVPIKYLLENPPNTYSNTVKVFPDENLPYGS
                     IPNQKDYKFESGSYPILFYKYKDYVIWGMTAKILENFLNFLSE"
     gene            29095..29433
                     /locus_tag="KR294_002044"
     CDS             29095..29433
                     /locus_tag="KR294_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3784 domain-containing protein"
                     /protein_id="HBH0240122.1"
                     /translation="MFAVGFVVIIALAFFILSVLLFNGKASMLLAGYNSMSKKEKARY
                     DKKKLCRSSSIVTFIVSIMLFIMAFLGYRIESGQMDEKKMVPFSIIFIIVILSSVFFN
                     ILYSNKKCKK"
BASE COUNT        10021 a         4728 c         3315 g        11513 t
ORIGIN      
        1 attaattaga atgtatgaag ttattcaaga aaatcgcaat agtattgcta tagagaaagc
       61 tgatttacaa gaactagttt ctgatatatc tcatcaaatt aaaactccta ttgcaaattt
      121 aaaaatgatt aatactactc tactaaatca aacatttaaa acagaaattc aaaaggattt
      181 tttaatggat atggaaaacc aattagataa attagatttt ttaatgcaat ctatggtaaa
      241 aacctccaga ctagagacag gtataatcac actatctaaa aagaaaaatt caatttatga
      301 aacaattgct acagcactta gtggaatttt gtttgatgct gaaaaaaaga atattgaagt
      361 tacagttgat tgtgacccaa atttatatat aattcatgac aagaaatgga cttctgaagc
      421 tatttttaat atattagata atgctgtaaa atacacaagt tctaatggta agatacgtgt
      481 agctacagaa tgttgggtta tgtatacaaa aatagatatt attgataatg gaaaaggaat
      541 atcagaaagt cgccaagcag aaatctttaa aagattttat cgtgaagaag atgtccatga
      601 catagaaggt attggaatag gtctctatct ttcaagaaaa attatatctc ttcaaggtgg
      661 ctatattaaa gttacatcag atattggaaa agggtcgact ttttctattt tcttacctaa
      721 taaataaatt tttaaaaatt tcatttgtaa tgattctgca acattttggt tttatactgt
      781 atttacaaga tgttaaggag gtattattat gagtatttta caagtaatta atttaaagaa
      841 atattatgga caaagttcaa acattacaaa agctcttgat ggtgtaactc tatctattga
      901 aaaaggcgaa tttatttcta ttgtaggtac atctggtagt ggcaaatcca cattattaaa
      961 tatgatggga ggattagata atcctacatc tggaaaggtt attataaagg gtaaggaatt
     1021 atctactatg tctgatgaac agcttacaat ctttagacgc agaaatatag gttttatatt
     1081 tcaaaattat aatcttgttc ctttacttaa tgtatatgaa aatattatct taccaatagg
     1141 attggatgga gagaccatag ataaggattt tataaatgaa attataaata tgctttctct
     1201 tgaagaaaaa ttatatgata taccaagtaa tctttctggt ggtcaacagc aacgtgttgc
     1261 tatagctaga gcacttgtaa caaaaccagc tattatacta gctgatgaac caacaggtaa
     1321 ccttgatagt agaactagtt cagatgtact gagtttactt aaagtgacaa gtaaaaaatt
     1381 caaccaaaca attgtaatga ttacacacaa taatgaaatt gcacaactaa ctgatagaat
     1441 tattcgtatt gaagatggaa aaattgttaa ctaggaggtg tagtatatgt ttagaaataa
     1501 taatcgcaca tttataagaa aaatagcttt aaatgattta aaaattaata aacttaaaac
     1561 atatctttca ggtatcatta taatgatttc tacatgttta ttattaacag tgaccttagt
     1621 ttcatataat gcctctgtag atttagttaa tgcatctcca tatcatgcta tatataaatc
     1681 tgtagatgaa aaagcaaaaa atatactata taaaaataaa aactttagtg gcgtaggaac
     1741 ttacaaatta attggaagta ataaaaagac agattgtatt atgtcgattg tttatgcaga
     1801 tgatacagca attaaactta tgaattttca accattgaaa ggcaaactac ctacaaataa
     1861 aaatgaaatt gctatttcag aaaaatattt acaggaattt ggtttagata aagatattgg
     1921 agatagcatt aaattaaatt attatgatga tattacgaat aaagaagttc aatgtgattt
     1981 tattattgtt ggatttctag aaaattatta tcaagataat gccaagcaat actatacagt
     2041 cgtttcaaat gattatttta agaatatagc ttctacacct ttacaaaata aaagtaatac
     2101 ttttgacgag tcaagacctg atactgtaga tgtattagtt aaactatcag aagaaaatac
     2161 agagaaagat tcagcttcaa ttaagacaca gttaaataaa attggtttat ctttaggtat
     2221 taagaaatat aatatatact taaatgataa ctatattgaa tcaaatttaa ttgatggtga
     2281 gcagattatt acagttttag tagttggaat agttgttctt ttttctagcg tttttgttat
     2341 atatagtatt ttttatattt cagttgttaa ttcagttcag atgtatgcta agttgaaatc
     2401 gttaggtatg acttcttttc agttaaaaaa aattatttct ctacaaggaa atattttgtc
     2461 aattattttt attccattag gggttatagc ttcttgtata attgcttaca taattcaacc
     2521 attagcatgg caaatgatag ctgatttatt tataatttta attttatcac tggtaatgtt
     2581 tttaactgtt agaatttctt tatttaaacc agctagaatt atttctaaaa tatctgctat
     2641 tgaagccatg caatatacag aaactaaatt tagaaaaaaa gcaaaaaatt ttagttatat
     2701 aaatataaaa aatctagcat taaagaatat cgagtcaaat agaaagaaaa atttgattgc
     2761 attaatatcg ctaagcatta gtggagtttt atttatttca atcgctaatc ttgctaattc
     2821 aatagatttc aaaaaacaac tatctcaaca atttgtctat aacgaagatt atataattag
     2881 cattaagagt gataacttat atgagcatat tacagaaatc caacaaaata atccactaac
     2941 agattctctt aagaatgaaa ttaaatctat tcatggagta aaaaaattaa ttgaatccaa
     3001 atcaattaaa agtaatatta tagaacctta catcaaagat agagacgaaa aacaatttat
     3061 tactctaatt aaaggtatta cgcctgaact ttcaaaatca cttgaagaat atattgtcag
     3121 tggaaaaata gactatacac atttagattc agatagttta attataaata aatatagaac
     3181 aaaatattat ggattaaatt taaaagttgg agatacagtt acatttaata tctttagtgg
     3241 aaatgatatt attaaaaaga aaatgaaaat tataggaatc attgacaatt ccaatacagg
     3301 aggtatgttt tttgcttcag acaaaacttt agaatctcta acaccatata atacaaattt
     3361 agatttttct attttaatag ataaaaagca ttctaaagaa gttgaagaaa agttgttaag
     3421 tataattcag aaaaattcaa atttaatgct ttattcatat gaagatgatt atagaatgat
     3481 tactagagca tttcaatata taattatagc ttcatacatt tttgttggtt taatttcttg
     3541 ctttggtata ctaaatatga ccaataccct aataaacagc gttttaatta gaaaaaaaga
     3601 gtttgcatta cttcaagccg ttggaatgac aagaaagcaa ctgcgaaata tgctttatag
     3661 agaaggtcta aacataagta tcaaagctat atgtacttca agtacactag gttattttgg
     3721 ttcaaatcta ctttgcactt ttataaaaga tgtaattaga ttagacttta ttaattttaa
     3781 attttctata tttactattt taattttttc attcgtatta attggtatac aagttttagt
     3841 gactgaatta cttgtaagaa atatagaaaa aaaatcactt acagaacgct tacgttctca
     3901 gtaagaatgt atataaaaaa tagccatttt ttatacaagt tttaatatga ttttttaaaa
     3961 gctataggga tagaaaattt tgactttaca taattttcta tccctatact tgtttttatt
     4021 ttatacagat acacttactt atatctccga gcaacatcac cagagacata aacaagcata
     4081 ttccttattt tctaaatatg tcaattgcat gacttgtaac ccctactaaa tcttcacgtt
     4141 cacaagtagc aaggtgatat tttaaatata atgcaaatgc atcatcatcc atagagtcta
     4201 ctgcttcacg catatataaa gccaaaccat ctgatgcgac ataatgcagt ctagttacat
     4261 taaatgcaga catcaaatca tcaatgtttt ctttacgtac aagctcaaac aaatcctttg
     4321 gttcagactt agcagcaaat gtctgtggat caatcaaacc tttttcaata tattcagata
     4381 cattaatatt tcctctatgg aacccctcgt caatgagaca gccatcagat ataacatatg
     4441 cagcaaaaac cacaccacca ggttttgtta cacgaattgc ctcatgtaaa gcttgttgtt
     4501 tatcttcttt gttataaaga tgatatagtg gtcctaacag taacgtaata tcatatttat
     4561 tatctgggaa aacagataaa tccatagcat taccctgagt aatgcttata ttttcatttg
     4621 attgagtatt tttatggaaa acctctatat tatgttcgac taattccact gcgtcaacat
     4681 catatccctg acgtgccagt gtgtgagaat aacgaccagt tgcagcgcca atttcaagca
     4741 cacaatcacc tgattttatg tacttatcaa tgtaatgcat agtagtgaga aattccacca
     4801 ttccatgttt taatgcaagt cgactatctt catcataagt attataaaag tcaattaagt
     4861 attgttttgt ttccataatt tcacctcttc tatattagtt aataaacatc aaatagacaa
     4921 attccaatct ggtttttctt gtcttataaa agctgttaat atatttttca acattttttc
     4981 agcactatat ctatctaatg ttaatttttt tgttgctgtt aagacagcta tgccatgagt
     5041 ataaagaaat aaatctaaaa atattacttt tgcacattcc aactctattc caatgctttc
     5101 cgaaaaaagt cttgcctttt tttcattgtc aatttcttta taaaaatcat ttgcctcttc
     5161 catcatcaaa tctaaatcat ttataaataa caacttaaat aaatgagttt cttcttgagc
     5221 aaattcaatg tatgaaagcg gaagcagtaa ataaggactt acacttttag aattactata
     5281 attaacaaca tactgattat agtattcata tgcaaaagca agaaattcat tttttaattc
     5341 attcatgttt tcgtaacaag taaaaattgg tcgagtggaa cactgtaatt tacttgcaat
     5401 actcctcgca tttacagctt caaatcccac ttctcttgta atatccaaga ctgtattcaa
     5461 aatcatttct tttgttatct ttactttagg tggcatatat gttcacctct ccattaaatt
     5521 tttataaaac acatatgtta tataactata gtaacatatc aagaaattat gtcaagaaaa
     5581 agctttgcat ttttttgcaa ttcctaaaac ttataaataa aacatgagtt gcaattaatc
     5641 tattaataga taacagcaac tcagattttc ctttaaatac tcttcttttt gtctaatatt
     5701 tcatatacac aatcttctat tgaattaata tctttttctt ttcttttttt agaatcaatt
     5761 aaaatgaaat acagtataaa acctacagca agtccccatg ttccgccttt agcagcaatt
     5821 acacctccca taagtccaat caatcccttc tcaacacctg tattacatag ctccattgat
     5881 agctttgtac ataaatatcc ttgaactaaa agtgttactg acaatgctaa tggtataaga
     5941 ggtgtagcaa tctgcgcaat tggataaaaa cagataaaaa ttgctgaaac ccatactaat
     6001 gtacccatgc cactaaaaac agactgcatg gcttcctttc caaccttgta cctttgagca
     6061 acacttcctg taagtgtcgc agctaatgga ccgcacattg gtatatatgg agaaaagatt
     6121 gccataaaaa tatttcttat cccacttata acattagacc tatttgaatt gaaatctata
     6181 tattcatctt ttctattttc actttcagaa agtactaagt tttcacctgt tataaaatca
     6241 ccaaaggcaa ttatgtatat cataaaagcc attggtatcc cttgtataaa taacattaca
     6301 cttggaaaac ctattccaaa aggagatact gtatttatca gatttttaaa atctactatg
     6361 taaactaaat tgtcaaaact aaatctagga atttctattt ctttactaaa tatacctact
     6421 attaaactca ctaaaatagc tgatactaca ccatattctc ctaaatgaaa taaaaattta
     6481 ttcttaactt ttagagtatc aaatctttca gaaaacatta caaaacaagc aaccaaaatt
     6541 cctactgtta tagatatagg ataagaatca aatctccctt taggattaaa ctctgatatt
     6601 atagtcgata taccgacacc cattagtatt ccacctttaa tagaatttgg tatcttacta
     6661 actaactttc cagctacacc agttataccc attaaaataa atattattcc taaatctatt
     6721 tgtaaagctg ttaatgcttg tattctttca atgcccatgc tgaactttaa caaatatgca
     6781 gttgtaagag ttatagaagc tgtaatccag ccaggtacaa ctgggtctcc cataaaaaca
     6841 tgcaaacagt ataatattga gttaatgata gccatactcc atgccacttc atagggtaat
     6901 cccaaaattt gtgtactaag gccaattgtg cctaaacttg tcatacttga tattatacct
     6961 tgaatagctt ctggtttctc aaatctgtaa tgtataaatg gaattcttat cttaaacatt
     7021 ccaaatttta tatgaggttg ttcccttcta gcgagtcttt ccataacttc actccacctt
     7081 tcaataactc ttataagttt acaactttat aattgtttat aaattatcaa tgtcattaaa
     7141 attagtatat aacatgcaaa ttatataaac aataaattaa atctataaaa ttgatagatt
     7201 ttgtgcatat atagaaagac cgcttcattt ttagttactt aaatcactta atattagtta
     7261 tttaaatcac ttgataaagg ttttttataa aattcaatag ttctattcca tgattcaaac
     7321 tgtccttttg aatttccttc tacagttcca cctgaagaaa aaatccctct actcatactc
     7381 atacataaag tctcctttag aggcataata tatggaattg gtaacggata acccatatta
     7441 ttgtatgtta ataattctac gttatatgga taattatttt cttcaaagat ttctaatgcc
     7501 tctaaacaag cttcataact attccatatg ttatcttctt ttccagcaat cataagtata
     7561 tctgctttgg aattttctat ttttattcta gcctcttttc tattctctgc tcttttaaga
     7621 cttttcttat aagtactatt aaatccaaat ggaatatctt ttgatatatt ttttttctgt
     7681 tcttcaaaga atatatcatt gtctactttg atatatggaa atggctctcc tttatatgac
     7741 catgatgaag tatcatttcc actcatcaat ccattaagag cttggaaaca ataaatgtga
     7801 ggttgtgata ctacaacctt tttaatttgt tcatatcttg aagcaagtaa aaaggccaat
     7861 tctccaccct ttgatgtccc atgtacaaat atttctttag tactggtaat ttcattttca
     7921 ctaatccact caaatacttt ttcaaaatat tctaatggaa cctcttctaa tttatctggt
     7981 aacccttcta aagcaaagta tgcaactgtt agtacattga atcctctaga tgcaagtgga
     8041 gctgctaaaa ggtctagagc gtctaaattt ccatcagaac cacctagcat taaaattgtt
     8101 ttattattag aattttgttt ataaaataat tttcctataa actcatcaga tatgtatttt
     8161 gtggtaatat cttctgattt aaatattctc tttaattcaa cttcttttct ttcaatagaa
     8221 gtttcaaata tcatattcat aattattggt ttatcaatag atatattttc tgcaaaattt
     8281 ttaccttcag ttttagattt ttccagcgaa taaattaacc ccatacaatt atcagcctta
     8341 taagtacctt ctataggttc aactaaatct aaatctactt ctcctttttc atttgaacaa
     8401 aacactccat aagatgaaaa ttcttctccc ttacaccatg gaaattccat tttcacactt
     8461 attttaagtt tagtatttgg aattaagtct gaaaccataa tcttaagtct ttcatccaca
     8521 aatgattcta cattgtatac atttactttc ataatctatt tctccttata ataattattt
     8581 atgttttata taaaacagct ttatctaata caagataaat aaatttttaa attaagacac
     8641 catattgact atttcatttt atcaacatat ttcatctttg tcaacatatt gtctttttta
     8701 gtaatttaaa attatggtct atatgaaatc cagttgattt ttggctaatt aaagatagga
     8761 atgctattag gtttagaata tatatattca aaataaaaaa ccactcattt aaagaatggt
     8821 ttttaatata aactatttgt tattaataag gatatttttt tatttaaatt tatataatcg
     8881 aacatctaat atttaatgtt taataaaatt atgcatttgc aaaagtatat atggcattaa
     8941 ctcttgctac atataaattc tcatcactac atccaatata tctagcatat ttttcaatct
     9001 tttcttttgc attttcaaca tcattttcat cgctctccat taactcattt atataaatat
     9061 ccattaatga cgctttatat tctcttatat catagcctaa aaattcagtc aatctctcaa
     9121 tttccttact aaaatctcca tcttctttta ccaaaaattc gtatacatct tccctatatg
     9181 gatttaaagt tattatttgt tttactactt tgcattcgtc agccttccca ataaaaccat
     9241 ctttataatt attaaataag gcattagatt tttttataga ttcttcatca atataagaat
     9301 gtaccgcagt tatacgattt tctataaggg catctacaac agcataatga attttaaaac
     9361 aatcattgta taaataattg ctcattttct ttattgtcga ttctatttct aagaagctcg
     9421 cgtggccatt ttttttattt ttatttggta taataaaagt tttattcaaa ttattaaaaa
     9481 gtctcttaaa atctaaatat ttttcacaat aaacactttt aaaggtatcg atatctatag
     9541 ttataattcc aaaacttact atagtctcaa ttcctttctt aaaagactct tctatatatt
     9601 tttctcctaa acttaaacct ctatcagata tttgctttag attttgaaaa ctatttaaac
     9661 aatctctttc aaagttttta gatatttcta aagcatataa tttaaagatt ttccttatct
     9721 tattataatt attttttgta tcatcaaatc tgataatagc tccatttaca tcaaaagtaa
     9781 tcattgagtt ttaacctccc cattagtttc atcaataaaa taaatttaat ataaacttta
     9841 taatcataat attaaactta tttatactat aattattaat ttgatgataa aagctatttt
     9901 ccttctaaat aaaaaatttg tctaaagttt ctaaaaaatt tagacaaatc ttaggttatt
     9961 actctttaaa ttatttttaa attattccaa atacgccaaa taatattggt ataaatatag
    10021 ctggtaacaa attggctact tttatattcg ttaatttaag tacatttaga ccaagtccta
    10081 taattaataa acttccagct gctgtcattt ctgtgactac aggatcactt aaaaatccat
    10141 ttaaaaatga tgctcccaca catataatac cttcatacaa aaatacagat attgcagaaa
    10201 acattacacc tatacctaaa gaagcagtaa atataattga agctattcca tctataacag
    10261 attttacaaa taaagtatca tgacttcctg taagaccact ttctaatgaa ccaactactg
    10321 ccatggctcc tatacagaat aataaactag atgatataaa accctctgct atagaatctt
    10381 ttttatttcc tttagaaaat ttactttgta aaaaagcacc caacttattt acccatttgt
    10441 caatatctat taattctcct atcagagcac ctacagctac ggatattatt gtcactaatg
    10501 tgttttttcc ttctagtgct cctgatatac caatgtacaa tacacataaa gcaattccat
    10561 tcattatagt atcgcttact ctttgaggta atcctccttt tattataaga cctactatac
    10621 atccacctgc aattgctaga ctatttgcta ttactccaaa cattttttct cccctcgatt
    10681 agctaattga aatttatcct attattaaaa cctaaacatc tatactttgt attggatatt
    10741 ttaaatattc caaaaattct tcaaaacctt ttctagatat atttacagtt ttagtattta
    10801 tgttaggatg aaaatttaag taatcttctt taattacatc tttatctatg taaagctcaa
    10861 cttttctttc tgtatcattt attaatgaaa aaggatttac acttccagga agaagtttaa
    10921 gtacattgta tagtctttca ggtgaagcaa acgataatct agaacttcct atcttatctt
    10981 taagtgagtt taaatcaact tgtttttctc ctttaactac aataagataa tacttatttc
    11041 ctttggcatt tcttaaaaat aaatttttac attgacaccc ctttgttatt ccatctaaaa
    11101 tgactaattg ctctgctgta tatacagctt catgctctac tacatcatat tcaacattta
    11161 atttatccaa aatatcatat attttagttt cattcatgct agattcattt tcatcttgtt
    11221 cttttttatt atttaaatca ctcatacttt tctccttaaa cacttcatca taatatcatt
    11281 gtgaggtatt attctactat agctattgct cttactggag ctccatcagc atcattatac
    11341 ttaaatggtg ctgctataaa tagaaatttt tctggaacat tttctaaatt tgtaagattt
    11401 tctatgatta tttttccttt ttcaaataaa atatgatgca cttcaaatac tgatgtgtca
    11461 tatctatcca ctgatagcat atctattcct atgcctttta tattagtatt agctatatag
    11521 tttgcagctt cttttgttaa tgtaggataa cctacatagt actgcttttt atcccaaaat
    11581 tttgaccaac ctgatttaaa tattataaaa tcactatttt ttatttcatc ttcatatttt
    11641 tttagatatt ctaattctat attctcattt cccttttcaa gttccaatac ataagctttt
    11701 ccaacaaaat tttctatatc caacttatct agggtctcac ctttagtata catatgtctt
    11761 ggtgaatcca tatgagttcc attgtgagaa aatacactaa ttaatgtttc ttgataacca
    11821 ttttcttcaa taatagctac tttcttgata tctggtctat taggctctgc atatacaggc
    11881 atgtcattat gtgtcacatg agttaaatca aaaaccttca tctttatata ccccctatgt
    11941 ttttattttc tattatatac ctaaattcat tttatttcta tcagatttta ttccattata
    12001 taccatacta ctatatattt tttataaacc tcaagggatt taccgaaaaa tcttggaaag
    12061 aattatcagt aaatataaca tcttcaccca aaaaacgttt ataccttcct tcttctttct
    12121 ttaaagtaat tctctgtttt tgtgaatgat tattaaaaac cattatctta agaggaggtt
    12181 tttttctatt agtctgcact ctttttaaca tgtattttat gtgcatatca gcttcaggaa
    12241 atgaatatcc acaaaatatt aaaaggtcag tatctcttaa agttttttct gtttcattcc
    12301 aaacattact taaaaatatg tttgacatat tcttaaaata tgttggtggc actataatag
    12361 gttctgttaa ctcaccacac tctaaacatt ttgtctctga actattttca ataagcttca
    12421 tgacaccacc ttcatgtggt gtaagagtta cactattaca aatggggcaa taaagccaat
    12481 tcaatgaccc atgtatctta tataatttga ttaatggttc ttttggtttt ctccaattta
    12541 actcctcttt aaaatttgta aactccacac cataatcaag cataattggc aaatcattct
    12601 tatctcttaa tccagtaact gtattgtcta tatgtatatc ataatttgca ctaataaaag
    12661 tagtatcaag aagcaaatca ttttccaaaa gattttcaac taaaagttta tgatatttat
    12721 tatctgttct aggtgtatta tgaattgctt cagccattag cagtattaaa tattgtctta
    12781 aaaaacgtat actatcactt ctgttattta gattttctag tccaaaattt ctaaatgctt
    12841 cttttctttg ttctgctaag tctaaaagac ctaaaacttc ttcaaaggta ggaaaatttg
    12901 cattatctat attatctttt actatatcaa tattgaacat ctgtttaaag aaaatataca
    12961 attctctatt cattttggta ttataatttg tgggatttag ttttttaaaa tattcgctaa
    13021 aaagttcatt ttgaataggt agattctctg ctgctgaagc tcctgctcct aaaaatattg
    13081 ctattttcat atagttcctc ctaatataaa tattactcct atttttatat ccattaaata
    13141 tccatatcat ttattttatg atacaacaat aaagctgtct tttactagaa aaaatcctat
    13201 tacaagacag ccttatatta tattaaatct ttaataattc gtaaatagaa agagcatata
    13261 tttgagtagc ttttataata tcctctacta ttaagtattc attagcttgg tgttctgttt
    13321 ctggttttcc tggaaaaata gctccaaatg caacacaatt atctaaagct cttgcgtatg
    13381 ttgctcctcc agatgaaagt ggtgttccat caagaccagt ttcttcttca tatacttttc
    13441 taagtgtctt aacaagaaga gtatcttctg gaacatagat tgaatccaag aaatcatatt
    13501 cttcataatt taaattgtat ttatctgtca ttttctttaa ctcttttaca aaatcatcct
    13561 ttttgtatgt tactggaatc cttacatcta ttcctgcaaa ttctttttcg ttatcaatag
    13621 ttactctacc tatatttact gttagtttac ctgatacatc atccttgcaa ttaggaatta
    13681 tattgtttcc attagcatct tcaccaataa cttctgctaa aaacttaatt atattagaat
    13741 ctatacctat attattaaga gctatacaaa gtctagccac tgcatttata ccagtatcac
    13801 ttgctgctga atggacactt tttccaatta tacagatttt attaccttca acagtatact
    13861 caaaatttaa tttatcaagt tcttttttta atttatcaga gtattttcca atatagattg
    13921 ctttacctgg aactgcattt aaagcctttc caactgacaa ctctatatca cttttgctat
    13981 cacaagtcaa atgaacttgt aaaagacctt tctctgcatt tgttattggg aatctagaat
    14041 ctggagtaaa tccatagttt ggtatttctt cattattttc tttatattta tttatacatc
    14101 tccaaagatt ttcttcatca gccccaaaaa tgaatcttat cctcttatta aagtctacat
    14161 ttaaatccat aagagctttc actgcataaa ttgctgatat tgtaggtcct ttatcatctt
    14221 gtgttcctct tccatacaat ttaccatctt ctaaaacagc ttcaaatgga gggtaattcc
    14281 agctttctaa atcaccttct ggaaccacat caacgtgacc aagtatacct atcatttttt
    14341 caccttgtcc tatttctgca tatccataat atccatcttt gtatactgtc ttaaatccta
    14401 aagatttaca taagtctaat atacctctta aagctttatc tacattttca ccaaatgggc
    14461 aattttcagt tgcttcagat ataacactag gtatttttac actttcttgt attgaagaaa
    14521 tcatttcatc ttgtagagaa tttacttttt ctttaatttg ctctttcata ttatcaccct
    14581 tcaattttca tcataatata ctaataaata ttttgacctt ttaaaaaaaa aatatgctta
    14641 ttttttcagt ttttttataa attcaatcgc ttttaaagtc cccatttttg aatggtcaaa
    14701 tgtaagtcca ccttgaaaat aaacattata aggaggtctt attggagcat ctgcacttaa
    14761 ttctatagaa gaaccttgta taaatgctcc tgctgccatt atgacttcac tttcgtatcc
    14821 aggcatgtcc caaggaacag gttttacata agaatcgact ggtgcagctt cttgtatacc
    14881 ttcacaaaaa cttattactt catcagcatt attaagtcta atacattgaa taatatcact
    14941 tcttaagtca tcatattttg gtaatacatc atatcctaat ttttcaaaag ctcttgagca
    15001 aaagatagct cccattacag cctgagatac tatataaggc gccaagaaaa aaccctgaag
    15061 tacatttcta gttgttccaa aagtaagacc acattctttt cctattccag gagaagtcat
    15121 tctataagat ataagctcaa tcaaatcttt tctaccagct atatatccac ctgtcaatgc
    15181 aagcccacca ccaggatttt ttattaaaga gccagccata acatctgctc caacatcagt
    15241 aggctctttg gtatctaaaa actcaccata acaattatca accattacta tagcttctgg
    15301 tttaacagac tttattactt ctatagcttc ttttatatca ctaattgaaa gtgattttct
    15361 ccaagaatat ccttttgacc tttgtatcat aacgagttta gttctatcat ttattttgtt
    15421 tttaattcct tctaaatcta agtttccatc ctctaaaaaa tctacatcat catatgtaac
    15481 accatactct ttcaatgaac ctttttcttc tcttatgcct ataactccct ctaaagtatc
    15541 atatggtcta ccagtaacag ataaaatttc atctcctggt ctaactatac cttgtataca
    15601 taaagtaagt gcatgtgtac catttacaat tattggtctt acaagagcat cttctgtatt
    15661 aaatacttta gaataaattt cctctatttt ttcacgacca atatcattat atccatatcc
    15721 tgtagtccag ttaaagtgca tatcacttag tttagattct tgcatagctt ttaaaacttt
    15781 atattgatta tattctctta tttcttttat ttcttcaaac ttatctttta tttcttccat
    15841 tatttcttgc gatagtttaa aagtatcatc atctattcca tagtagtctt ttaataattc
    15901 ttttgtctca ttaagcattt tatcacctgt ctctttatta ttttatttaa acatgtaaag
    15961 gagactattt tactaaaaca aataaattat agtttataag ttagtataag tctcctctca
    16021 atcatcttaa attaaattaa ttatctatct gttgttatta ttattgttgt tttggttttg
    16081 atttgttaga ttaatatact ttccaggttg tatagttgat acagcatgtt tataaatcat
    16141 gttttgttgt ctattatccc cttctattaa tattatataa ctatcaaacc cctttacaag
    16201 ccctttaact tgcactccat taactaaata tatagtaaca ggtatccttt ctttccttgc
    16261 attatttaaa aacaaatctt gtaaatttaa aactgtattt ttcattagat ttgtaccctc
    16321 ccaagattaa attgaacttc taaaatattc ctaccttata ttctatataa gttatgacaa
    16381 attttcaata ttaagttgta tacttaaaaa tttatatatt attttataga atctttaata
    16441 tataagatta tttcattttt taattcgtct atattttcat attggtctaa atcaaaccat
    16501 tttgctgttt tatatctttt aaaccatgtt atctgacgtt ttgcatacct tctagaatct
    16561 cttttaatta tttcaatagc ttcttcgtat gtatattctc catccagata ctttaatatc
    16621 tctttataac ctataccttg cattgatatc atatcttttt taaatcccat acttaaaagt
    16681 ttttttgcct cttcaaccaa tccattttta atcataatat caactctcat atttattctt
    16741 tgatacaaat gttctctatc tctatttaga actattatta ttggttgata ttcttcatta
    16801 aattttaaat cacttgaaaa atcattcatt ttcttaccac ttagacaaac ttcaagagct
    16861 cttatgaccc ttttagtatt gtttttatgg attctattag cagattcttc atcaagttct
    16921 tttaacttat tatgcatgta atctattccc ttttcagcaa gctgtttttg aagttcttct
    16981 cttaattcat tattggcatc agattgtgca aaatccatat tatatattaa agagtttaaa
    17041 taaagtcctg tgcctccagt tactaaaaca catttttcct tttcatttat ttcatgtata
    17101 tatttttttg ctctttgttg aaactctgaa actgaaaatg gatagtcagg cttaacttca
    17161 tctataaggt aatgcttcac tccttgcatc tcttcctctg taacttttgc acttccaata
    17221 tccatatatt catatatttg catagaatca gctgaaatta tctctgcatt catatctttt
    17281 gctaatttta ttgacaaatc tgtttttcca acagcagttg gacctgtaag tattataagt
    17341 ggtatttttt tcataacatt cctttccata tattttaaat atccaaatat tttacataat
    17401 tcttttaaac attttttcta tttctgtctt agatatttcg accattatag gtcttccatg
    17461 aggacatgta aatggattct cacacttttc tagctgttcc aataaacttt ttatttcaat
    17521 atcgtatatt ttatcatttg cttttatagc agacctacat gccatagatg caaatctctc
    17581 tccttttaaa tcataattac ttgtaatttc ttctatatta tcaattattt gaagtataaa
    17641 tttctcagtt tcaggtactc caaatatagt aggaacacat cttaccatta tatgattatt
    17701 gccaaaaatt tctagctcaa aaccaaattt cataaataac tccaagttat tttcaatttg
    17761 aagcatatct atatttgata cttcaataac cactgggtct aaaagtattt gcatatttat
    17821 atcttgtcta tagaacttct ccatatatct ttcatatagt attctttcat gtgcagcatg
    17881 ttggtccaac aaatacatag aatcgtcttt gctcaaaatt atataagtat taaatacaac
    17941 tccaattaca aaatatccgt ataaagaaaa cttgcgtttt gaactacaca agtattcttc
    18001 ttcactgtcc ttaatactat ctcctaagta ataatttcct tcatttttaa ttccatcaac
    18061 ttgaaactct tcttgtatat tatcatttgc actatcttca cttagataat taatgttttt
    18121 tacatcatct tctacacttg catttaggac ttcacttact gattgaaatt catttattgg
    18181 tttttcactt gataaagtaa caacttcaat gacttcatcc ttacctttag taatattact
    18241 atttttagga gtagattcta ataaatcatt atttcttaat ttataatctg tacttttttc
    18301 tctactgtta atagcgattc taggttgtgt ttttttatca ctataagtag catattttcc
    18361 aataagattt gagtgtatta atttaacctt taaaaaatct ctaagttcta tatacacttc
    18421 ttgttctttt tcaaatttaa tttcaagttt attggggtgt atatttacat ctatacatga
    18481 tgggtctact tctatattta agaagcacac tgcatgttta cctattggaa ttatagactt
    18541 ataactttct gttattgcat ctatgattat tttacttttt acaaatcttt tatttatata
    18601 gatatgttgt aagtttttat ttgaacggta tatattgtta ttacctatat atccattcat
    18661 tttaaagtga ttgcacttaa actctacatc tattatattt tccgttattt cttttccata
    18721 tatacttcta atagtgttta caagttttcc atcccctgga gtatttagca tctgtttatt
    18781 gttatttgta tatttaaatt gaatgtttgg attacctatt gcaagtttat ttatcaaatc
    18841 acttatgttt atagtttctg catgagtaga ttttaaaaat ttctgtcttg ctggtgtatt
    18901 aaagaaaata tcttttataa tgatggtagt tccattagta gaacctattg gttctttcga
    18961 tattattttt ccaccttcaa catatatttt agttcctatt atttcatctt tagttttagt
    19021 cgtcatttct aattttgata cagctgaaat agatgccaat gcttctcctc taaaaccaag
    19081 agagtataaa tcatacaaat catcaatttt tttaatttta ctagtagcat gtctcaaaaa
    19141 tgatttttca acttcacttg aaggtattcc tattccatta tctgtaatct taattagact
    19201 ttttcctcca tcaattatat ctatggaaat tttatttgca cctgcatcaa tggagttttc
    19261 aataagttct tttactacag aagaaggtct ttctacaact tcacctgctg ctatcttatt
    19321 tatagtcaaa tcatctagga tgttaattat atttttcatt tttacacctc taagatttta
    19381 tttcttttgc ttttctttga agattataaa gagagtttat agcatctaat ggagtcatat
    19441 ttaaaatatc cagatttaaa atttcttctg atagtatatc tctatttaca ctatcaaaag
    19501 agatttgagt taaggctact tcttttacag aatcttcttg attaattttc tctttatcat
    19561 cattttgctt cattaaagca acttcatcat ttaatgcttt aaatttagaa tttaatttat
    19621 cataatcctt ttttatatgt ttgtagtctt ttactataag ttcatgttct atttttagag
    19681 attcatattt attcttaaaa ttactttgat ttaccttaac taattcttcg tccaaattac
    19741 tattaattat attattgttt tctttatctc catttattgc aacactgttg taaacatgat
    19801 ttttttccaa gtctttaagt atatattttg ctctttctat gacttcgtct ggtaatttag
    19861 ctaatttagc aacatatatt ccataactct tgtctgctcc ctgaggaatt atttttctta
    19921 aaaatattat tccttcccca tcttctttga ctgctattga ataattttta acctctttaa
    19981 actcttcttc taaatcagta agttcatgat aatgtgttgc aaataatgtc ttacatctaa
    20041 tatttttttg aatatattcc actattgacc atgctaaact tataccatca taggtactag
    20101 ttccacgacc tatttcatct aatataacta aacttctctc tgttgcattt tttaatataa
    20161 gggatacttc gttcatctct accataaaag tagattgacc ttgagataaa tcgtcactag
    20221 ctccaactct tgtaaatatt ctatctaata ttggaatatc agcagactct gctggtacaa
    20281 atgagcctat atgtgccata agagctatta tagcagtttg cctcatatat gttgatttac
    20341 ctgacatatt aggaccagtt attatgttaa taatgttttc tccacgattt aaataagtat
    20401 catttggaac gaaattttcc tctcctacta tattttcgac aacaggatgt ctaccatttc
    20461 ttatatcaag tttattattt tcatttattg ctggttttac gtagttattt atatgtgcaa
    20521 ctgttgcaag ggacacaaaa acatctatat tagctatagt cttagccact ttttgtattc
    20581 tatctatgtt tttatatatt gtatctctta tctctacaaa tatctcgtat tctaaagatt
    20641 taatcttttc ctctgcatgt agtatctttt cttctatttc ctttaattct ggagttatat
    20701 atctttctgc attactaagt gtttgctttc ttatatatgt ctcatctagc tttgcctgtt
    20761 taaagttggc ttttgttatt tctatataat acccaaaaac tttattaaat cctattttta
    20821 atgatttaac tcctgttttt tctctttccc tgttttctat ttcctttaca agaaaggctc
    20881 cattcttaga aatctctctt agttccttaa gttcatcact aaaatctgat ttaattatgt
    20941 ttccatcttt tatggttatc gtaggttctt ctagaatagc ttcatctatt aaattgtata
    21001 tatcatctaa tttatccatt tctgaaacat actcttttag gatttttgca tttgataaat
    21061 ttatagtatc ttttaaatta ggtaactttt ctatcgaatt ttttaagtga attaactctt
    21121 ttggtgttac tctctcaaat gctatctttc cacatattct ttctatatcg tatatatttt
    21181 taagtatatc atttaggtct tctcttaata taaagtcatc ttttatttct tctattacat
    21241 ctaatctatt ttcaatttta gatttattta tcaaaggttc ttctacatat tttcttaaaa
    21301 gtctacctcc cattgctgta gaagttttgt caagtacatg taataatgaa ccttttttct
    21361 tattccctct tatagtttga gtaagttcta aattagttct agtaaacata tctagaacca
    21421 tatattctga tgaattgtat atatttatat tattaatgtt agatgttatt tgtttttgag
    21481 tattgtatat ataattcaga agaattgata agcttgactt tattagacct ttatcatcaa
    21541 actttagttt ttgtagataa acatctggaa aatattcttt taatatattt atatccaaat
    21601 agttatcact aaaactttca tttatgtata tattacttac agtagctata tctctaagct
    21661 tttctataaa gtctaaatca tttataatta tttcagttgg atggattttt gcaatttctt
    21721 caattacctt atcttcattt aaacatgttg cattagtttc tcctgtactt atatcaacat
    21781 aagttagacc tatattagta ccatccttat acaaagataa taaataatta ttctttttat
    21841 tttcaagtaa atttccatct aaaactgtac caggagtgat gacccttata acctctcttc
    21901 taacaattcc ttttgctgta gatgggtctt ccatttgttc acctattgct actttatatc
    21961 cattttcaac taattttgat atatatgaat tggctgagtg gaaaggaaca ccacacatag
    22021 gagcacgttc ttctaaacca caagcttttc ctgtcaatgc tatttcaaga gcttttgaag
    22081 ctactaatgc atcttcaaaa aacatttcat aaaaatctcc aagtctaaaa aacagtatac
    22141 agtctttata tctatttttt acttcaagat actgtttcat cataggagtt aatttattca
    22201 tatctatttg cattatcaaa cctccttctt ttctaattaa atattatatc atagtagatg
    22261 attattatta acacaatata taaaattttg acatataact aaaaacaatc caaaatgtat
    22321 actcacattt tggattgcta agtttaatgc ttattaaata aaaatatttt tttttacaat
    22381 aaagatatta tttctttttt aagtttaatg atattttcaa ggttatcttc atttaacttt
    22441 ctactatcta taacaaattc tttctttact attgatggtt tttttgaaat aacataaatt
    22501 ctgtttgata gcattatagc ttcgtcaata tcatgagtta taagaagtat tgttgaattt
    22561 acttttttct taacatctaa aagccatttt tgcatggatg ttttagttaa tgaatcaagt
    22621 gccccaaaag gctcatctaa aagcattatg tcattagaat ttataaaagt tctcaagaag
    22681 ttagctctct gtctcattcc tccagaaagt tctgaaggat atttatcttc atatccgctt
    22741 aatccaaaca cctcaaaata aggttttacc attgacctag ctttactctt tttttctttt
    22801 tttaaaatta gtggtagtga cacattatct attatagttt tatatggcaa gagtaaatct
    22861 ttttgataca tataactata cttaccattt atattcactt tgccactatc ataatctgta
    22921 agtttagtta taatattaaa aatagtactt tttccacatc cacttggccc taatatagaa
    22981 acaaactcac cttcataaac atcaatactt atatctttta aaacttcaat atctttataa
    23041 gtttttgata cattttctat agatactttt acttttttat tgtggtaaaa attcatttgt
    23101 gtaagcatca cttgccttca tatccttatc tattaattta tattctttta agaatgatgt
    23161 atagttgttc catacactat ctttcatttc tccccatcgt ggtgcatcat ctttgtactt
    23221 gcttgctaaa tattcttgac tctttaaagc tagtttttca tctacttcag gtgcatgttt
    23281 tactaaaatt tttgctgatt cttctggatt ttttattgca tattcataac cttttgttgt
    23341 agcttttaag aattttttag caagctctgg attattttta agcacagttt cattagaaat
    23401 tataagtggt gtataataat ccaatctctc atctaaatct tttactggta taaagtttaa
    23461 gtcatatcca attaaatcag ctttaactgc atcccaacct tcaaatatcc atgcaaaatc
    23521 tacagttttc atagctgcaa agaaatcatc ttgaccagta ttaactatct ttaacttatt
    23581 aaaatcagct ccatttttct tcataactgc tttaaaaaca gcttcttctg atggagagcc
    23641 ccaaccacca taagtttttc cttcaaaatc tttagctgtt gttatattct tttcttttgg
    23701 tgatgcaaac ccagaagtat tatgttgtat aacagttgct acagctttta ttggaagtgg
    23761 atcttcacta gtctttgcat aagtaacttg ttcttgatag cttataccaa agtcagcttt
    23821 tcctgttgct actaaagttt ctgctccact ttcaggtggt tgtactattt caacatccaa
    23881 accttcttct ttatagtaac ccttatcaag tgctacaaat aatccagtat gatttgtatt
    23941 tggtgtccaa tcaagcacca tagttacttt tttagaagaa gtatctttat cattgttttt
    24001 gtctttattg ttatttgaag aacatccagt tattgttgcc aatgtaaaaa cacttactaa
    24061 acctaatatt cctaactttt taaaattcat aattgcctcc ctcaaatacc tttaatctat
    24121 taatctatgt cttataacaa ctttttttac agcctgtaca attcctacaa acattaaact
    24181 aaatataact actaatatag tagatgcaaa tactttatca agtgcatatg cactttttga
    24241 cctaagcata taaacaccaa gtcctttcgt tccacctagc cattctgcaa cagttgctgc
    24301 cattacagca tacgttgcag atattttaag tccagaaaaa aatttatcca ttgccatagg
    24361 aaatttaagg tgaatgaatg tattaacttt atttgagtcc atagtcttaa ataaatttaa
    24421 ataatcttta tcaatattct caatgccatc tacaaaactt attaatatag gaaaaaaaca
    24481 agtaagcatt accatcaata cttttggcat tgttccaaat ccaaaccata tcataaagag
    24541 tggtgctata attattgtag gtatcatctg tgtaaccaac ataataggat aaagacattt
    24601 ttttattatt gatacaaaat ccatcaatat tccaattacc aatgatatta taattgcgac
    24661 tataaaacca agtattgctt ctcctatagt aaccacagca tgtatggata aattttgata
    24721 atctttaaaa aacacattaa ttatatctac tggtgtgggt agtatatact gaggaacttc
    24781 taaaactcct accatagatt gccaaagaat aagtataaac aaaaatgttg ctattggata
    24841 tatactatct ttgactttat ctatgatttc taagtttttc atctatagtc agacctccag
    24901 ctttttcatc tactctagct actgttatga ctctttcaca tccaagatta aaagggattt
    24961 tatgtacctt ttttaataat tcaaaaactt catcaaaatc accttcaaca gtagtgctca
    25021 ttgctcctat ttcacattta agaccacttt tttcaatttc agcaatacaa gcatctacta
    25081 ctttatacat ctcttcttca cctttgtaag gtcttagtgg cattactgct atgtctgcga
    25141 ttaccattta aatcactcct ttaaaaataa ttaataccta ctaggtatat tttgtttttt
    25201 attaaaaaat tttattacta aaaagatatt atatttaaat aaaagaaaag tcttatccaa
    25261 aataggataa gacttatttt tatcttaact ggtctcccta cactggcatt atccaaacag
    25321 gttcaaaggg tcgagataaa atctcctctc agcacattag ctccccgaaa tatattatat
    25381 cttttctact tgattatact acacttatca tattttaaca aattttttat ttatattaga
    25441 tattttatcc gttcaaaaat atctaatata aattgtacat tattacacca aataaattat
    25501 cttaaaatgg taatttatca acatcttcca aaactagatt aactgaattt tctagttttt
    25561 attttgctat ttcaagcata tttggatgta tatcaattcc atacaaatat tgtgctaaat
    25621 ttctgttttc actcatctaa tttgcaatcg ttacaaatta cagattagaa atagctttta
    25681 gactctactt atctttatct acaaaaaatc cttcaataaa ttcattaata atattcagta
    25741 atctaaaaat aaacctctat ctagattttt aagatacaag ccttttagga agtatctttt
    25801 gtgataatat aaaaattact catcattatc atcaaaatcc tcagcaacca acattttaga
    25861 taagaatcaa actctataat ataattattt tatccaattt atttttgaga aataaaatat
    25921 ttttttaatt tttaaatttt ttaatatgca ccttgaaaaa agaaacgttt tcctatatta
    25981 tggtaatagt agaataaaac taaataggca aaactagaga aatttagtga cgcaaagcta
    26041 tagggactaa gacttatgaa atgagttatg tcagccagtt gccaaagaga tattttcttt
    26101 ttgtttttat gaatgttttt tagggggata tatgatatat gtttatggat aaaatggata
    26161 gatgtacaca tatactaact gcatatatat gcagttcacg cgattactgc aattttatag
    26221 atacacaatt aaatgatttt atactagaat atggagagaa tgtggtagaa tcttgtttgc
    26281 atcaagtgat ggtattggta agcagatata attaaagaaa ttttattttc tagaaaaccc
    26341 tttttagttt tatctacgtt ttataattca ttaaagaact aattaaaata agcttcatta
    26401 tatatttttc ataaagtaaa cagttgagtt tatctcatat actgtttacc ccaattacat
    26461 aattctaata atatagattc taatgattta ccacgtttag tagacaaata ttcaactttt
    26521 ggaggaatag tcggataaga aatcctctta ataagtccat ctctttcaag atactttaat
    26581 tcttgtgaca gtatcttatg acttatatga acaacttctt tttttaattg actgtaacgt
    26641 attggctctt gttttaaaat atgccataaa ataattgccc tccatttact tcctatcaca
    26701 gtcatggtaa aaccaattga acaattaaaa tctttttgtc tttcttcaat atttggaaat
    26761 tcttcaaaat tattatctat atccatctca atcctctctt tcaaaatagt aagtatctaa
    26821 ctaaaaagtg cattcttgtt tagcgtacta attcgtaata taatcttgat tgtagtatag
    26881 agccttacat aatactactt ttttagatgt atatgtttaa actttaatat agacatatgt
    26941 tattttatta attttattta aacagataat aataaataat aatttatctc aagttttcta
    27001 tgtagataaa ctaatctaat gtttagaaag gattatataa tatgaataaa aaatttcgtc
    27061 tttatcaagt tgactcatta caaaagaaaa atttacaggt aatccagctg gtgtaattac
    27121 aaatgctgat ggcttatctg aatcacaaat gcaaaaaata gcaagagaat taaataattc
    27181 agaaactgct tttattttca ataacttggc taaaaatcat caagaaaatt atgatgtaca
    27241 tatcagattt tttacactaa ctaatgaggt tcctatatgt ggtcatgcta ctattgctgc
    27301 ccattatgtt agagcagtag aaaaccaatt caataacaaa acagtatttc aaaaaactag
    27361 tgctggaata ttaccagttg atattataaa aaaagataat gattatgaaa taattatgac
    27421 acaaggaaaa attgaagtat ctccaccgtt acaacaaacc tatcaaaaaa gattacttaa
    27481 tgcatttggt attttaaagg aagatattcg tacagattgt cctattgcca tatcatctac
    27541 aggacattca aaagttatga ttggaataaa ggaattatca acattaaata gtttatctcc
    27601 aaatttatat gaattatcga aaataagtca agaaataaaa tgtaatggat attatatttt
    27661 tacattacat aataaagaaa ctctacaagt tcatggaaga atgtttgctc ctgcaattgg
    27721 tatttcagaa gaccctgtta caggaaatgc taatggaccc ttaggtgcgt accttgtaca
    27781 ttataaagta atacctacac ccaacacaga gtttatattt gaagcagttc aaggagaaac
    27841 aataaaacgc aaaggcaaga tgttagtaaa agtaattatt ttagataata aaccagttga
    27901 agtaaaaata attggaaaag ctgtaattgc attctcaaca aacatagaaa tctaattata
    27961 gattccttct aagtaaattt ttgaactttt taatactaat ttaataacaa actaatttat
    28021 atacaatcaa attaattttt ttattatttg ttaatatata tttatcatta tattatataa
    28081 taatatagat agttactata tcttataatt agataaatca taattatata ttattgttaa
    28141 aactcaatta tataattttt aataatatta ttttaggagg taaaaatgat aaacgatatt
    28201 aaaaataaat tcaaaaatta caaaccatat ataaatggat acaagaatat gaagagagca
    28261 tctgttttaa ttccaatagt agaaataaat aacacacact atatattatt tgaagttcgc
    28321 tcaaaaaatt tgaagcatca acctagtgaa atttcttttc caggtggtaa aatagaatca
    28381 ggtgagactc catatgaagc tgttattaga gaaacttgtg aggaacttgg aacttttagt
    28441 gacaatatag aagtaatatc aagtcttgac ctccttataa caccagtaaa gtttatcata
    28501 catccatact taggatatat aaaaaatatt aataatttaa atataaacaa ggatgaagtt
    28561 gaccatactt ttttggttcc tataaaatat cttttagaga atcctccaaa tacttatagt
    28621 aatactgtaa aagtttttcc agacgaaaat ctaccatatg gttcaattcc aaaccaaaaa
    28681 gattataaat ttgaaagtgg aagttatcct attctgtttt ataaatataa agattatgta
    28741 atttggggaa tgacagcaaa aatactagaa aactttttaa attttttatc agaataacac
    28801 tcataataaa tcatcaaaac ttttacataa gaaatttata aaagtttcta aatttaacaa
    28861 ttctaaaata tcaataacta tattttgtag cactttttta ttttattatt gtttgaatat
    28921 ttgatggttt tcaatgcaat ttcaacataa atactatgta ttagtgtata ctgttgatga
    28981 attaaagtat gataatctat ttaataaagt atgaagtaaa tgattttaat gtgcctttat
    29041 ggtaaaatta ctaataagta ataaaattaa ttaaaatata tggaggtgct tataatgttt
    29101 gctgtaggat ttgttgttat aattgcactt gcctttttca ttttaagtgt actattattt
    29161 aatggaaaag ccagtatgct actagcaggt tataactcta tgagtaagaa agaaaaagca
    29221 cgatacgata aaaaaaaatt atgtagaagt tctagcattg ttacttttat tgtctctata
    29281 atgctattta ttatggcgtt tttgggatat agaatagaga gtggtcaaat ggacgaaaaa
    29341 aaaatggttc ccttttctat aatatttata atagtcatac tttccagtgt attttttaat
    29401 atcctctact ctaacaaaaa atgtaaaaaa taaatagttg taagttgagc agttaattat
    29461 aaaagattga ctgctttttc atgtatattg actactctta ttaaatattt taacatttaa
    29521 aaatctatgt aaaaataatg aatatagtac aaacttctaa taatgatttt acctttg
//
LOCUS       DAEPKC010000046        28916 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.046, whole genome shotgun sequence.
ACCESSION   DAEPKC010000046 DAEPKC010000000
VERSION     DAEPKC010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 28916)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28916)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28916
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.046"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            150..971
                     /locus_tag="KR294_002045"
     CDS             150..971
                     /locus_tag="KR294_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HBH0240123.1"
                     /translation="MIKKEISNFRGSSDYVVSPELMASVNVAIALEKPLLIKGEPGTG
                     KTMLAQAISNELKKDLVIWNIKSTTKAQEGLYVYDTVQRLYDSQFGGEGVDDISKYIK
                     YGKLGEAFSSNQQVILLIDEIDKADLEFPNDLLWELDKMEFYINETKETVRAKQRPIV
                     IITSNAEKELPDAFLRRCIFHYIEFPDRDMMEEIVKVHFDKVEEHLLEQVMTTFYWIR
                     SLKDIQKKPSTSELIDWIQALTLSGMPIEKIEKEVPFAGILLKNNEDIESMQRHL"
     gene            992..2188
                     /locus_tag="KR294_002046"
     CDS             992..2188
                     /locus_tag="KR294_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HBH0240124.1"
                     /translation="MFIEFFYLLRSRGLNVSLNEWMTLIEALDKGLCYSNFSNFYYLC
                     RMILIKSESDFDKFDAVFLEYFKGIEHQEEIPEEIMNWLKKPDIDLEEFERLEQNPNI
                     NLDKLRAKLEERIKEQDSPHNGGNYWIGTGGTSELGHSGKGQTGIRIGGNSTYGRAVL
                     EVAGERKYRDFRDDEVLNMRQFQVALKRLRQFSTRIDAPKTELDLDKTIEETCNNAGY
                     LKLFFEKPRKNTVKLLLLMDSGGSMRGYSTLCNTLFQSVSKSNHFKDVKIYYFHNCIY
                     DRLFTTPECWLSKSINTEWILKNIDKNYKVIIVGDASMSPSELLHIGGNYRGPYNYTP
                     GIEWLKRFKRKYSKIVWMNPELRDGWDSINYWYQTQRMIQSEFNMFPLTVKGLEKALK
                     NLMVSR"
     gene            2355..5753
                     /locus_tag="KR294_002047"
     CDS             2355..5753
                     /locus_tag="KR294_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HBH0240125.1"
                     /translation="MIIINYELIVKYNGDILRLEEELGVSVEILNSSYAIITSSNEED
                     VNILLTYPEIEFIEKPFILQTQDVQSFSSTGITGFKNRTGLTGKGTIIGIIDSGIDYT
                     LPVFRDSDGRSKILYYWDQSIQGNPPEGFREGTLYTNEDINNAIDGSMYIPISTTSLH
                     GTHVAGICATIASDARIIVVRVGNIQTDIFSRSTEFMRAIKFILDRALELRMPVTLNI
                     SYGSNEGSHRGTSLFEQYIDDMCLFWKNNIVVAAGNNADKGGHKRIRLQNNITEEVEF
                     IVGEGERILNINIWPDFVDDFSVHLVNPSNNQTQAISLTSGEIRNTLGETRITGYFYP
                     IAPYSLTRRVTLQLSSNTQITPGLWKIVFEPIDIVTGNVNIYLPTSEGLNRNTRFLIP
                     TQELTVTVPGTASRVITVGSFNSRTDIVSIFSGEGDTQLGVFKPDLLAPGEDIVSFLP
                     GGTSGALTGTSMATPHVTGVCSLFMEWGIVNGNDLFLYSQKLRALLLKGARRLSNQSY
                     PNNSSGFGFLNLSDIDLYTLSNINQDLETEDIGYRSINKSFKDEENSYKFIDGYNMQI
                     HNDLENEIYISKNASRQSGILSGIDIVHTPEFEEELAGLGMSQRFFKISDSLGVLSIN
                     NTDYNSIQRVLQLPSIIRTVSTTKMTLLGEINRGTFGGVVATEEMGVNFFKNNPNINI
                     TGRGTLISIADTGIDYLHPDFIYPDGTSKIVYLWDQTKEGTPPDGFYIGTEYTREDIN
                     RAIAENDPSLSQDEVGQGTMLSGICAGLGNVNSEYAGIAEDSELIIIKLGKIDDFYNS
                     AMLFAASQYAYKKAFELGRPLVINMSLGTSSLAGLTNRSNSEKAFFTRGLCITAGAGN
                     EGNTQTHTSGIIPYVGGSVEVELELNEDEEELSLELWLNRPDKADVIIVSPTGEESKS
                     VGISNYNKVTGLFDLEGTEYSITYIYPTTFSGQQFTNVTLKNAKRGVWKIRLVGVYII
                     TGRYNLYLPNRELLKSGTRFREVDPFYTINYPAIQDDLITIGAYNTINGSLWQSSSRG
                     PTIEDRLKPDIVAPGVNIIAAYPGNTYATITGTAAASAHAAGAAAMYFQYTFVDGRYP
                     NQAYVQKIKTFMQAGARKDSNTVYPNTNSGYGLLDVRGMFDVLR"
     gene            5763..7436
                     /locus_tag="KR294_002048"
     CDS             5763..7436
                     /locus_tag="KR294_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family peptidase"
                     /protein_id="HBH0240126.1"
                     /translation="MEKSYCIIYQGDIESALQENGINRYMVLNSQLAVIYVPLDFDET
                     ILNNIIQVAWWEESEPMSSLIEITNNVNNGETITTAAETDYIYENPYNDITGRGILLA
                     VIDSGIDYLHPDFINDDGTSKVLYLWDQEANTNPPPEGFIFGSEFTRSELNIAINRND
                     GSLSQDNIGTGTLVSGILVGNGRINSQYRGITTESDLIVVKLKSYTDTYYAGRINYSV
                     SDFLAAITYVTNIARTENKPLIINLTIGVKSSAVATTSILDTFNILSSAGVVVVSGAG
                     NQGNTDIHYSGRFSSVGEVQDVIIQDGDDYALDITLNTNGPDKVGAQIISPSGEVSHD
                     IRYSPDFYIYRGKFNLENTTYAMRFIYPYITSGKENLEIRLRDIKPGVWILRLTSELI
                     INGEYDIYLPNKNLIAPDTRFLDPDSVATITMYAASDDVITVGTFNNKTDSMWIGSSK
                     GPIRGRGIKPDIVASGVDIISTYKNGTYNTGTGTGVSSSIVTGVLALLMEYLEKQDNV
                     PRLSLFTQVLKTYLILGATKLEIYTYPNVSQGYGILNLKNTIQQIANTL"
     gene            7709..7903
                     /locus_tag="KR294_002049"
     CDS             7709..7903
                     /locus_tag="KR294_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3787 domain-containing protein"
                     /protein_id="HBH0240127.1"
                     /translation="MESKKARALKGKDNKRLKSSLLVGNESTAAWADVEKLKPHSKVS
                     IPSIKGVEEAKDWVDNGSKL"
     misc_binding    8072..8305
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            8382..9779
                     /gene="asnS"
                     /locus_tag="KR294_002050"
     CDS             8382..9779
                     /gene="asnS"
                     /locus_tag="KR294_002050"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HBH0240128.1"
                     /translation="MQKEFITVKELYREKEQYIGKTVKVAGWIRTSRVSKNFGFIELN
                     DGSFFKNMQIVFDEKVENFKEVGKLAISSSILVEGELVSTEGAKQPVEIHAKSIVVEG
                     ESDSSYPLQKKRHTLEYLRTIAHLRPRSNTFSAVFRVRSIAAYAIHKFFQERNFVYAH
                     SPIITGSDCEGAGEMFRITTMDLNDIPKTEDGKIDYTQDFFGKEANLTVSGQLNAEIM
                     ALSFRNVYTFGPTFRAENSYTGRHASEFWMIEPEIVFADLEDNMELAEDMIKYVISYV
                     LENAPEEMEFFNSFIDKGLLERLNKIVNSEFIRITYTKAVELLIESGHEFEYPVEWGC
                     DLQTEHERYITEQIYNCPVFVTDYPKDIKAFYMRMNEDGKTVRAMDLLVPGVGEIVGG
                     SQREEREDVLLDRINEMGLREEDYWWYLELRKFGTATHSGFGLGFERIIMYMTGMSNI
                     RDVIPFPRTPKNAEF"
     gene            complement(9952..11127)
                     /locus_tag="KR294_002051"
     CDS             complement(9952..11127)
                     /locus_tag="KR294_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBH0240129.1"
                     /translation="MNLEKIKKFFGFPLDKKHKDNVEKELCNYLYHTGKIICIIIVIS
                     QIIMMISISAREGGPFVTPRRQWYFYMYVTLFCVSSVFMFVFSYLWNKKKDCCTFYIN
                     LWIIYVTFFCLWGCVITLLDQLGGNDLSVFSYIMLAAAAFSVLKFGESVIVFGGCFLF
                     LNLFLPGIQTIPGNEFSNIVNTFFITSLAIFVSTMLYRNRVFTYYDKLLISQQYEEIS
                     HINNLLNDKVMTDDLTKMNNRRYLEDILQKKLISHANQEPITGMMIDIDYFKQFNDNY
                     GHQKGDYCLQNIAKVILDFTSSENEHAIRYGGEEFFICIFNCNEADAKLKSECLRKII
                     ESCNFERDDVPLKCVTVSIGVYTKKIGKTITLNEFISNCDKALYTAKEQGRNCVAFY"
     gene            11546..12910
                     /locus_tag="KR294_002052"
     CDS             11546..12910
                     /locus_tag="KR294_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HBH0240130.1"
                     /translation="MGEKKINNMNYSHNNYSKKTGEPTRKIKNSHITLKSKEEKICSS
                     CNKENNTKDNYCKFCGNELYEIASLRPLETKLDLKSKIKELSYHANKRGVFLTTFTTI
                     FILFIIALIFKAIITIQFNDISYLVNPAHIILALNLGQISVSMSTMMGSGFINANIGL
                     LILLIIPILVLLISNLIFMRKRCRDSKTVLANSLGVGIFYGLVLAILSIFTNVKTSSH
                     SMLEYGYALEYSYEFFSVLLNGFVLGFICTYITTYKKSYEKENMYLSLFSNSIRTFIL
                     GYVLVLVILLVLTISDSSYLNELDMSSYSNGLNLFTILPQIASYMWAFANGISVTIIN
                     STVSMFTLSSSSLFGDTKLMFYAMGALSMLILLLNGYKLRFKYNTDSIRPIIVFSIYY
                     AFLMGILALFSTFILDSNINFFNTTNYGTTLIMQFKVLQAIVISFVYSFVISLIGYKL
                     NSAD"
     gene            12932..13423
                     /locus_tag="KR294_002053"
     CDS             12932..13423
                     /locus_tag="KR294_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HBH0240131.1"
                     /translation="MEGNTNNKVDDKFSKVKKKFGSGKFKVELYKEKSKLNREIDDIQ
                     EKKAKIFLEMGILTYQKIREDSINDNSFDKFCDELLELDKLIYEKNMEINEMEMAESN
                     VTCECGYVGNVNDKYCAECGKKFELENECDDFIICGYCESEIDTEAEFCPCCGRKIIM
                     DLE"
     gene            13695..14366
                     /locus_tag="KR294_002054"
     CDS             13695..14366
                     /locus_tag="KR294_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HBH0240132.1"
                     /translation="MLDKVKGRLIVSCQALENEPLHSPFIMGRMAKAAMEGGAVGIRA
                     QGVEDIIEIKKVTGLPVIGIIKRNYEDSDIYITPTKKEVDELLTTGCEMIALDATNRV
                     RPNNEDLKELIKYIKENGVLVMADISNYDEAIKAQEYGVDCVSTTLSGYTPYTKTLEG
                     PDFVLMKRLVKDLEIPVIAEGKVNTPQDLKKVFELGVHSSVVGSAITRPQLITEKFVK
                     AIEIN"
     gene            14451..15317
                     /locus_tag="KR294_002055"
     CDS             14451..15317
                     /locus_tag="KR294_002055"
                     /EC_number="4.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003452648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate lyase"
                     /protein_id="HBH0240133.1"
                     /translation="MKGIYSALLVSFDKEGNINEKGLRQIIRHNIDVCKVDGLYVGGS
                     TGENFMLSTDEKKRIFEIAKDEVKEEIKLIAQVGSVNLKEAVELAKFTTDLGYDAISA
                     VTPFYYKFDFEEIKHYYNTIINSVDNRLIIYSIPFLTGVDMSLDQFGELFENEKIIGV
                     KFTAADFYLLERMRKTFPNKLIFAGFDEMMLPATVLGVDGAIGSTFNVNGVRARQIFE
                     LTKNEKISEALEVQHVTNDLITDILGNGLYQTIKLLLEEQGVEAGYCRQPMKEATDEM
                     KSRAKEIYRKYF"
     gene            15350..16852
                     /locus_tag="KR294_002056"
     CDS             15350..16852
                     /locus_tag="KR294_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003462875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
                     /protein_id="HBH0240134.1"
                     /translation="MVGFTWIDFAILVVYLLAVLFAGLLFSKKEMKGKEFFKGDGTIP
                     WWVTSVSIFATLLSPISFLSLAGNSYGGTWILWFAQLGMFIAIPLTIKFFLPLYSRLE
                     IDTAYEYLEMRYESKGLRVLGALMFIIYQIGRMSIIMYLPSIVLAGLTGIPVNVLIIV
                     MGVIAIIYSYTGGLKAVLWTDFIQGMVLIVGVTGTLFYLIASINGGFGTVMDTLTTGH
                     KFLASNEVMFDKNILSTSAFIIFVGAGLNTFSSYVSSQDIVQRFTTTTDIKQLNKMTY
                     GNGVLSMGLATVFYLIGTCLFIYYTQNPDLAQTVQQDQVFASYIAYELPVGITGILLA
                     AIYAASQSTLSTGLNSVATSWTLDIQTIITKDISMEKQTKIAQYISLGVGILSIAVAI
                     VLANGEIKSAYEWFNSFMGLVLGVLAGIFVLGAFCKKATKMGAYVGFIVSAILVVYLK
                     YRMPEVTSWAYSLITITTSVVVGTIVSAIEAKVKAKVSLPKAETTVYYEK"
     gene            16982..17434
                     /locus_tag="KR294_002057"
     CDS             16982..17434
                     /locus_tag="KR294_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HBH0240135.1"
                     /translation="MIFGNINHSKTYSTLHEDLLRCFEYAKDNSLIDYEKGTYTIDGD
                     DIFVNIVEYKTCEKEDRFWEAHKKYIDVHLMLDGCERIDINFIENLEQKIYEEKGDFL
                     PLDGKNNGYMELRKGDFLVCYPEDAHMTGIKVLEKENIKKAIFKVLVR"
     gene            17594..18397
                     /locus_tag="KR294_002058"
     CDS             17594..18397
                     /locus_tag="KR294_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240136.1"
                     /translation="MENIDVFLLIGQSNARGLGNPKESIIPNENCFEYLSTDEIINMR
                     CELETSEGDGTIAPAFSNEWNKLTGNKVCFIHNAKDGSRIKNWNHDNNWFLNDTIEKF
                     NTGCTTLSKHYNIENKYVIWIQGESDAKYGSDVLYYKESLKKIAYRLKEECMIDKMFV
                     SLTGYWLGEDEYFIRTRRIAAAQESACSECDILCVGSKIAMQFHDRGLTIDDVHYTQE
                     GLNMLGEDLCKNIYKYHITKEKSVLSDTIDLSEARKYICELEKISKRFV"
     gene            18455..19342
                     /locus_tag="KR294_002059"
     CDS             18455..19342
                     /locus_tag="KR294_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBH0240137.1"
                     /translation="MKNYVCIDVGGTSIKYGFIREDGFIIDKSSLDTEAKEKGGEGIL
                     AKIKDIVKKYIEENEISGICISTAGMVDPVEGKILFALEELIPNYKDMQLKKEVEKEF
                     NIKCEVENDVNCAGLGEMWLGAGRGATSSICLTIGTGIGGCIIINNKLINGFSNSAGE
                     VGYMNVNGSSFQELASTSSLIKKVAKIKNLNENDLNGKIIFDLAKNNDEDCLKELDNM
                     IKSLAVGIANICYVINPEVVILGGGIMAQEKFLKPKIDKALKEVLIERVYKNTNIEFA
                     KRQNDAGMLGALYNFLNKI"
     gene            19361..20209
                     /locus_tag="KR294_002060"
     CDS             19361..20209
                     /locus_tag="KR294_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBH0240138.1"
                     /translation="MSILEQLESPTFKVTKSDKLLIAYIKENIDDVFYKPISQIAKES
                     NIGEATITRFVKKMNFNGLQDFKVTLAQEISTINKKNIINKNIQNDEPALDTAKKLLS
                     SNVTTLENTVEIINSKDVHDCARLIINAKKVYFIGIGYSGIIAQDSNYKFMRIGLNCV
                     SFDSSHTMIMMSSIMEEGDLIIAISHSGETEEIIKTVKLARANNAKIISITENKNSEL
                     KDISDVHLSYVSGETVLETGSISSKLAQFFIIDLVYTQVVKELSNEAIERKIKTTNAI
                     KLFKNE"
     gene            20272..20961
                     /locus_tag="KR294_002061"
     CDS             20272..20961
                     /locus_tag="KR294_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBH0240139.1"
                     /translation="MSKLKDYNIDKVIIFNNLSTKTKNQLKEKVKLKRLQKKEILFYE
                     KDSLDSVYILLEGKVSIFKISENGERKVIFILNSGEVINDITLDASKNSTVGCEAFEN
                     SIVAYYSIEEFLEIMQNDFQLTKDIISYMERRIRRLYRQLKNSISIKVDKKLAAKLYR
                     LSREFGVCCGEWTLLNVNITVTYLADMLGCKRETVSRMIKVLQKEELIKIDNKGFYVK
                     ETELSRYFKNN"
     gene            complement(21291..22481)
                     /locus_tag="KR294_002062"
     CDS             complement(21291..22481)
                     /locus_tag="KR294_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009271880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBH0240140.1"
                     /translation="MSNVKRKDSKNRNLRNGESQRKDGRYVYKYTDIYGKPQFIYAWK
                     LVPTDKTPAGKRDDISLREKEAQIKKDLDDGIDTAGGKMTVCQLYDKKNSQRKNIKRA
                     TEKGRQYLMNALKNDPLGMRAIDTVKQSDAKEWAIRMSERGYAYKTIDNYKRSLKASF
                     YMAIQDDCIRKNPFEFKLSDVLEDDTEPKVILTPEQEERLLAFMETDKIYSKYYDEVV
                     LLLETGLRISEFCGLTTHIDMQNRILNIDHQLLRDSEIGYYIDTPKTKNGKRKIPLTE
                     RAYQALQRILKNRVKAQPLVVGGYSNFLFLNREGLPKVAGNYVGMVRGLIKKYNKYHK
                     DKLPNITPHSFRHTYCTNMANKGMNPNTLQYLMGHANITMTLGYYAHGTFQSAKAELE
                     RLAC"
     gene            complement(22559..22762)
                     /locus_tag="KR294_002063"
     CDS             complement(22559..22762)
                     /locus_tag="KR294_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HBH0240141.1"
                     /translation="MNNTDVPIWEKYTLTIEEASKYFRIGEKKLRKLAEENIDAGWVI
                     VNGNRIQIKRKQFEKIIDTLDEI"
     gene            complement(23144..23392)
                     /locus_tag="KR294_002064"
     CDS             complement(23144..23392)
                     /locus_tag="KR294_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004613734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH0240142.1"
                     /translation="MKHTFKKPSYYLLSQAMDGDEKAIEKVLAFYDPYISKCCLRPLY
                     DEYGNVYIVVDMELKGLIREALIKMILGFDIALEIEEE"
     gene            complement(23396..23815)
                     /locus_tag="KR294_002065"
     CDS             complement(23396..23815)
                     /locus_tag="KR294_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005361151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBH0240143.1"
                     /translation="MKPSDFQKTVQCRFESCLKKVVRHVVKDYQQGLKRRKEKEISFC
                     ELPEIMVENLAVWDDYETDYTIFNVCGNDIRVYDDELAEALKQLSERNRETLLMYYFL
                     EMNNEEIAKKQNISRSGVFQNRHNSLALMRKLLKEKR"
     gene            24236..24595
                     /locus_tag="KR294_002066"
     CDS             24236..24595
                     /locus_tag="KR294_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0240144.1"
                     /translation="MRKTKETHTFDFRPLGLAIREAREKAGLSRNDLGDKVFYGERHI
                     ADIENIGSHPSFQLFHDLVTMFNISVDEYFYPAEKVAKSTARRQIETSLDLLSDNELK
                     IIQGTIDGILNSRENKK"
     gene            complement(24714..24902)
                     /locus_tag="KR294_002067"
     CDS             complement(24714..24902)
                     /locus_tag="KR294_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006863419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HBH0240145.1"
                     /translation="MKNEMWVLCPICNNKTRTKVREDTELINFPLFCPKCKTETLINI
                     KHGKVTIIKEPDAKTQSR"
     gene            complement(24924..25148)
                     /locus_tag="KR294_002068"
     CDS             complement(24924..25148)
                     /locus_tag="KR294_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008393106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240146.1"
                     /translation="MIGIKKRDIKKALKAGAKAGGSSYADVLADIEATIDEVMNSTDP
                     EVQANFKKYFGNKRPTPEEYIYKITKKTRV"
     gene            complement(25516..25797)
                     /locus_tag="KR294_002069"
     CDS             complement(25516..25797)
                     /locus_tag="KR294_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBH0240147.1"
                     /translation="MLIVEFTEKEDAVFQQAVEWLSSKLAYTPASFNQQKKGFDIDPL
                     TRTFTNEEGTSIYLTAKEFDLLYFLSSHKGQVFTKEQIYEKVWGYDNFY"
     gene            complement(25791..26306)
                     /locus_tag="KR294_002070"
     CDS             complement(25791..26306)
                     /locus_tag="KR294_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016285890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBH0240148.1"
                     /translation="MKSKPVKVGLRTIKTVLSAFLCFLIDSLRASSVPFYAVIASILC
                     IQPDMENSLSVAKNRELSTIIGGILGMLFLLMERIFLPIQPEILRELTLSILLIPIIN
                     LSVLLKQKKGTFLTCVVFLCVTVTHEKDISPIWFAWNRIVDTSLGIGISLAVNSFPFH
                     KFKVGGTMGKY"
     gene            complement(26296..26796)
                     /locus_tag="KR294_002071"
     CDS             complement(26296..26796)
                     /locus_tag="KR294_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015393784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbhB/YbcL family Raf kinase inhibitor-like
                     protein"
                     /protein_id="HBH0240149.1"
                     /translation="MYISSIGISNGIIEKKYGSHGVQFNENDVPTYSIPFKIENAPDK
                     TVSFAFILEDKDAYPVTGFIWVHWLGANLTRSELKENESQTAKDFIQGANSWTSILGN
                     QQTREQTSCYGGMAPPDKAHIYELHVFALDKLLDLKNGFYLNELYQEMEGHILEEAVL
                     KGLYEK"
     gene            complement(26884..27249)
                     /locus_tag="KR294_002072"
     CDS             complement(26884..27249)
                     /locus_tag="KR294_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009291267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0240150.1"
                     /translation="MKLRDEYTCPLELIHDMIKGKWKPIILWRLRLGATSLSKLENDI
                     DGITQKMLLEHLKELIDYGFVDKKTFSGYPLHVEYFLTEDMGNQILEALRIMQHIGIE
                     YLRKNGMENELTEKHVIPD"
     gene            complement(27233..27784)
                     /locus_tag="KR294_002073"
     CDS             complement(27233..27784)
                     /locus_tag="KR294_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBH0240151.1"
                     /translation="MKKALLIIDVQNDYFPNGKCQLYKPEIALNTIKDLLKIFRKQNL
                     PIIYIRHESIHGTFFNPNTNGVQIHNDIKPLDTETVIVKHYPNSFYETNLQNKLVEIE
                     VTKLVVCGMMTHMCIDTTIRAAKDYGYEITLISNGCATKELKWNGVNIPADTVQSIFM
                     ASLNQKFANVITSTEFLSNEITR"
     gene            complement(27874..28233)
                     /locus_tag="KR294_002074"
     CDS             complement(27874..28233)
                     /locus_tag="KR294_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002583503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0240152.1"
                     /translation="MKLRESYTCPLELVHDIIKGKWKTIIIFQLRNGKCSFSELHHSI
                     AGITQKMLLEQLRELKHFGLIDKKTYDGYPLKVEYFLTGQGEKMLSAIKIMQEIGIDY
                     MVEHGMTEILDEKGICY"
     gene            28371..28730
                     /locus_tag="KR294_002075"
     CDS             28371..28730
                     /locus_tag="KR294_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0240153.1"
                     /translation="MRKTKETHTFDFRPLGLAIREAREKAGLSRNDLGDKVFYGECHI
                     ADIENIGSHPSFQLFHDLVTMFNISVDEYFYPAEKVAKSTARRQIETSLDLLSDNELK
                     IIQGTIDGILNSRENKK"
BASE COUNT        10547 a         3797 c         5025 g         9547 t
ORIGIN      
        1 taaaaattaa atattttaga ggtgatttta tttagatata gaattttaga ataatactat
       61 acaaatgtat tgtattatta tttttatatc aaaaatagta ataaagtcta tatacattta
      121 gaaaatactg tttaaaagga gtaggattta tgataaaaaa agagatatct aactttagag
      181 gaagtagtga ttatgtagta tcaccagaat tgatggcatc agttaatgtt gctattgctc
      241 ttgaaaagcc acttttgatt aagggcgaac ctggaacagg taaaactatg ctagcacaag
      301 caatttcaaa tgaattaaaa aaagatttag taatttggaa tataaaatca actacaaaag
      361 cacaagaagg gctttatgta tatgatactg ttcaaagact ttatgatagc caatttggag
      421 gagaaggtgt agatgatatt agcaagtaca taaaatatgg taaactagga gaggccttta
      481 gctcaaatca acaagtaatt cttttaatag atgaaataga taaggcggat ttagaatttc
      541 caaatgactt gctttgggaa ttggataaaa tggagtttta cataaatgag acaaaagaaa
      601 ctgtaagagc taaacaaaga ccaatagtta ttataacttc aaatgcggaa aaagaacttc
      661 cagatgcttt tttaagaaga tgcatatttc attatataga atttcctgat agagacatga
      721 tggaagaaat agttaaagta cattttgata aagtagaaga acacctattg gaacaagtaa
      781 tgactacttt ttattggatt agaagtttaa aggacataca aaaaaagcct agtacatcag
      841 agttaataga ctggatacaa gcattaactt tgagtggaat gcctattgaa aaaatagaaa
      901 aagaagttcc ttttgcagga atactactta agaataatga ggatattgaa tctatgcaaa
      961 gacacttata gttaatagga gctggataat tatgtttatt gaattttttt atttattgag
     1021 gtcaagagga ttaaatgtat ctttaaatga atggatgact ttaattgaag cattggataa
     1081 aggactgtgc tattcaaact tttcaaattt ttactatctt tgcaggatga ttttaataaa
     1141 aagtgaaagt gattttgata agtttgatgc agtgtttttg gagtatttta aaggtataga
     1201 acaccaagaa gaaattccag aagagattat gaattggctt aaaaaaccag atatagattt
     1261 agaagagttt gaaagattag aacaaaatcc aaatataaat cttgataaat taagagctaa
     1321 attggaggaa cgaataaaag aacaagattc tcctcataat ggtggtaatt attggatagg
     1381 cacaggaggc acttcagagt taggacattc aggaaaaggg caaactggta tacgtatagg
     1441 tggaaattct acttatggta gagctgttct tgaagttgca ggagaaagaa aatatagaga
     1501 ttttagagat gatgaagttt taaatatgcg tcaatttcaa gttgcactaa agagacttcg
     1561 tcaattttct actagaatag atgctccaaa gacagagctt gatttggata agactattga
     1621 agagacttgt aataatgcag gatatttaaa gttatttttt gagaagccaa gaaaaaatac
     1681 agtgaagctt ttattgctta tggattcagg tggttcaatg agagggtata gcactttatg
     1741 taatacatta tttcagtctg taagtaaatc aaatcatttt aaagatgtaa agatatatta
     1801 tttccataac tgtatttatg atagattatt tacaacacct gaatgttggt taagtaaatc
     1861 tattaatact gaatggatat taaaaaatat agataaaaac tataaagtta taattgttgg
     1921 agatgcttct atgtcgcctt ctgagttgct tcatattggt ggtaactatc gtggtccata
     1981 taattacaca cctggtatag agtggcttaa aaggtttaag agaaagtaca gtaaaattgt
     2041 atggatgaat ccagaactta gagatggatg ggattcaatt aattattggt atcaaactca
     2101 aagaatgata caaagtgaat ttaatatgtt tccattgact gtaaaaggtc ttgagaaagc
     2161 attgaaaaat ttaatggttt caagataaag taaatataaa tgatggtatg atttattcaa
     2221 aattgtacca tcattattta tttttttaat atacctatta taaattgtat aactgaaact
     2281 taaaaaatta tatagtctaa tacattttag actcacacaa aacatataca ttaataataa
     2341 ttttagaagt cgaggtgatt ataataaatt atgaattaat tgtaaaatac aatggagata
     2401 tattgaggtt agaagaagaa ttaggtgtat cagtagagat acttaattca tcatatgcaa
     2461 taataacatc aagtaatgaa gaagatgtaa atatactttt aacttatcca gaaattgaat
     2521 ttatagaaaa gccttttata ttacagactc aggatgtgca aagtttttca agtacaggaa
     2581 taacaggatt taaaaataga actggtttaa ctggaaaagg aactataatt ggtataattg
     2641 attcgggaat agattatact ctacctgtgt ttagagatag tgatggaagg tctaagatat
     2701 tatattattg ggaccaatct attcaaggaa atccaccaga aggttttaga gaaggaacat
     2761 tatatactaa tgaagatata aataatgcaa tagatggaag tatgtatata cctatttcaa
     2821 caactagctt acatgggaca catgttgcag gtatttgtgc aactattgca agtgatgcca
     2881 gaataatagt ggttagagtt ggaaatatac aaaccgatat tttttcgaga agtacagagt
     2941 ttatgagggc aattaaattt attttagata gggcattaga attaagaatg cctgttacat
     3001 taaatataag ttatggaagt aatgaaggtt cacatagagg aacatcttta tttgaacaat
     3061 atatagatga tatgtgttta ttttggaaaa acaatatagt tgtagcagct ggaaataatg
     3121 cagataaagg aggtcataaa aggattaggc ttcaaaataa tattacagaa gaagttgagt
     3181 ttatagttgg ggaaggagag cgtatattaa acataaatat atggccagat tttgttgatg
     3241 attttagtgt acatttggta aacccatcaa ataatcaaac acaagcaatc tctctaactt
     3301 caggtgagat aaggaatact ttgggtgaaa ctagaataac tggttatttt taccctatag
     3361 caccgtattc tctcacaaga agagttactc tacaattaag ttcaaataca cagataactc
     3421 ctgggttatg gaaaattgta tttgaaccaa tagatatagt aactggtaat gtaaatatat
     3481 atttgccaac ttctgaaggt ctaaatagaa atactagatt tctgattcct actcaagagc
     3541 ttactgtaac agttcctgga acagcaagta gagttataac agtaggtagt tttaattcaa
     3601 gaacagatat agtatctata ttttctggtg aaggagatac acaattaggt gtttttaaac
     3661 ctgatttatt agctccaggt gaagatatag tatctttttt accaggaggt acaagtggag
     3721 cattaactgg aactagcatg gctacacctc atgttacagg ggtttgttca ttgtttatgg
     3781 aatggggaat tgtaaatgga aatgatttat ttttgtattc acagaaatta agggcattac
     3841 ttctaaaggg agcaaggaga ttaagtaatc aatcttatcc aaataattca tcaggatttg
     3901 gttttttaaa tttatcagat atagatttgt acactctatc taatataaat caagatttag
     3961 aaacagagga tattggatat agaagtatta ataagtcatt taaagatgag gaaaatagtt
     4021 ataagtttat agatggttat aatatgcaaa tacataatga cttagagaat gaaatttata
     4081 taagtaaaaa tgcaagtaga caatcaggaa tactatcagg aatagatata gtccatactc
     4141 ctgaatttga agaagaacta gctgggttag gtatgagtca aaggtttttt aagataagtg
     4201 attcattagg tgtactatct ataaataata cagactataa tagcatacaa cgagttttgc
     4261 aacttccttc aatcataaga actgtatcga ctacaaagat gacattactt ggagaaatta
     4321 atcgaggtac ttttggaggt gtagttgcaa cagaagaaat gggcgtaaat ttctttaaaa
     4381 ataatcctaa tattaatata acaggaagag ggactctaat atcaattgca gatacaggaa
     4441 tagactatct acacccagat tttatttatc cagatggcac ttcaaaaata gtatatttat
     4501 gggaccaaac aaaagaagga actcctcctg atggttttta tattgggaca gaatatacac
     4561 gagaagatat aaatcgagct atcgcagaaa atgaccctag tctatctcag gatgaagttg
     4621 gtcaaggaac tatgttgagt gggatatgtg cagggcttgg aaatgtaaat agtgaatatg
     4681 caggtatagc agaagattct gagctaataa taataaaact cggcaagata gatgattttt
     4741 ataatagtgc aatgctgttt gctgcatctc agtatgcata taaaaaagct tttgaacttg
     4801 gaagaccatt agttataaat atgtctttag gtaccagtag cctagcaggt ttaaccaata
     4861 ggagtaatag tgaaaaagcg ttctttacta gagggttatg tataacggca ggagcaggaa
     4921 atgagggcaa tacacagaca catacatctg gaataatacc atatgttgga ggttctgttg
     4981 aagttgaatt agagttaaat gaagatgagg aagaattatc attagaactt tggttaaata
     5041 gaccagataa agctgatgta ataatagtat ctcccactgg tgaagaaagt aaaagtgttg
     5101 gaatttcaaa ttataataaa gtaacaggtt tatttgattt agaggggact gaatattcta
     5161 taacatatat atacccaaca actttttctg gacagcaatt tactaatgtt actttaaaga
     5221 atgcaaaaag aggtgtatgg aagattcgat tagtaggagt ttatattata acaggaagat
     5281 ataacttata ccttccaaat agagaacttt taaaaagtgg aactagattt agagaggtag
     5341 acccttttta cactataaat tatcctgcga ttcaagatga tttaataacc ataggagcct
     5401 acaatactat taatggtagt ttatggcaaa gttcatcaag agggccaact attgaagaca
     5461 ggttaaaacc agatatagta gcaccaggtg ttaatataat agctgcttat cctgggaaca
     5521 cgtatgcaac tataactggt acagcagcag caagtgcaca tgcagctggt gctgctgcaa
     5581 tgtattttca atatactttt gttgacggta gatatccaaa ccaagcatat gtgcaaaaaa
     5641 taaaaacttt tatgcaagct ggtgctagaa aagattcaaa cacagtatat ccaaatacaa
     5701 attctggata tgggctcttg gatgttagag gaatgtttga tgttttaaga taggagggat
     5761 ttatggaaaa atcttattgt ataatttatc aaggtgatat agaatctgcc ctacaagaaa
     5821 atggaataaa taggtatatg gttttaaata gtcagcttgc agtaatatat gtacctttag
     5881 attttgatga aactatttta aataatataa tacaagttgc ttggtgggaa gaatctgaac
     5941 caatgagcag tctaattgaa ataactaata atgtaaataa tggagaaacc attacaacag
     6001 cagctgaaac tgattatatt tatgaaaatc catataatga tataacaggg agaggaattt
     6061 tattagcagt tatagattct gggatagatt atttgcatcc tgattttata aatgatgatg
     6121 gaactagtaa agttttatat ttatgggacc aagaagcaaa tacaaatcca cctccagaag
     6181 gttttatttt tggaagtgaa tttacaagaa gtgagttaaa tatagccata aatagaaatg
     6241 atgggagttt gagtcaagat aatataggta ctggaacttt agtttctggt atattagttg
     6301 gaaatggaag gataaattct cagtacagag gtattactac agaatcagac ttaatagtag
     6361 ttaaattaaa atcatataca gatacttatt atgctggaag gataaattac agtgtttcag
     6421 attttttagc agctataacg tatgttacta acatagcaag aacagaaaat aaaccactga
     6481 taataaattt gactattgga gttaagtcaa gtgctgtagc aactacttca atactagata
     6541 cttttaatat attgagtagt gctggtgtgg tagtagtgag tggtgcagga aatcaaggga
     6601 atacagatat tcattattct ggcagattta gcagtgtggg agaagttcaa gatgtaataa
     6661 tacaagatgg agatgactat gctcttgata taacactaaa tacgaatggt ccagataaag
     6721 tgggagcaca gataatatct ccttcaggtg aagttagtca tgatataagg tattctccag
     6781 acttttatat atatagagga aaatttaact tagaaaatac tacttatgca atgagattta
     6841 tttatccata tattacctct ggaaaagaaa atttggagat aagattaaga gatataaaac
     6901 ctggagtatg gattttaaga ttgacttcag aacttataat aaatggagaa tatgacatat
     6961 acttgccaaa taaaaatttg atagctccag acacaaggtt tttagaccct gattcagtag
     7021 ctactataac tatgtatgct gctagtgatg atgtaattac agttggtaca tttaacaata
     7081 agactgatag tatgtggatt ggttcttcga aaggaccaat tagaggaaga ggaattaagc
     7141 cagatatagt agcttcaggt gtagatataa tatccacata taaaaatgga acatataata
     7201 caggaacagg aacaggagtg agcagttcta tagtcacagg tgttttagcc ttattgatgg
     7261 aatacttaga aaaacaggat aatgtaccga gattatcatt gtttacacaa gttttaaaaa
     7321 catatttaat attgggtgct acaaaacttg agatatatac atatccaaat gtatcgcagg
     7381 gatatgggat tttaaattta aaaaatacga ttcaacagat agcaaatact ctatagataa
     7441 gaacctatgt aaaattataa ttgattatta gtttaattgt atcaaatact ttagatagag
     7501 tagaaaaata gcataaaaaa taaatatgaa aattaaaaaa cagttttata ttttgaatac
     7561 acaaagtaaa tattttgtat ataaataggt ataaattaag tattgaaaag atatgatgtt
     7621 aatttaaaaa taattataat ttagacttat gaattttatt tgtaaaattg ctaaaactat
     7681 tacaaaataa ataatagagg tgatagtttt ggaaagtaaa aaggcaagag cattaaaagg
     7741 taaagataat aaaagactta aaagttcact tttagttgga aatgagtcga cagcagcatg
     7801 ggctgatgtt gaaaaattaa aacctcatag taaagtttca ataccttcaa ttaagggtgt
     7861 cgaagaagca aaagactggg ttgacaatgg aagtaaatta taaaattttg gaaattgaag
     7921 taataaagaa gtaatgaaga taagtattta ttatcattat gtaaggtaga attattatat
     7981 tttaaataac aatcagtatc aattatataa atttattgac taaaaattta taaattggta
     8041 taattttgtt aattagcaga aataataaaa gataaatact gtgaagagaa gagtagatat
     8101 aaaatgtagt tctagcgagt tgaggatggt gaaagctcaa tacgaggttt atattgaaga
     8161 acatcttgga gtttctaatc gaaagcttat ttagtaagta gacttagacg gaaggcaccg
     8221 ttataggctt taagcattgc ttaactaaga ggtcattatg acaactaggg tggtaccgcg
     8281 agagtaatag tctttcgtcc ctttatatag ggatgaaggg ctttttttat tgaaattata
     8341 tttaaaagaa attaataaca attatactag gaggatttaa aatgcaaaag gaatttataa
     8401 cagtaaaaga attgtacaga gaaaaagaac agtacatagg gaagactgta aaagtagctg
     8461 gatggataag aacatctaga gtatctaaaa attttggatt tatagagcta aatgatggaa
     8521 gcttctttaa aaatatgcag atagtatttg atgagaaagt agaaaatttt aaagaggtag
     8581 gaaaattagc aataagctca tctatacttg tagagggaga gttagtatct acagaagggg
     8641 ctaaacaacc agtcgaaata catgcaaaaa gcatagttgt agaaggggaa tcagatagtt
     8701 catatccact acaaaagaag agacatacgc ttgaatattt aagaacgata gcacatttaa
     8761 gaccaagaag taatactttt tcagctgtat ttagagtaag atcaatagct gcctatgcaa
     8821 tacacaaatt cttccaagaa agaaactttg tatatgcaca ttctccaatc ataacaggta
     8881 gtgactgtga aggtgcagga gagatgttta gaataacaac tatggattta aatgatattc
     8941 caaaaactga agatggcaaa atagactata ctcaagattt ctttggaaaa gaggctaatt
     9001 taacagttag tggtcaatta aatgccgaga taatggcact ttcttttaga aacgtttata
     9061 cttttggacc tacatttaga gctgaaaact cttatacagg aagacatgct tcagaatttt
     9121 ggatgataga gccagaaata gtttttgcag accttgaaga taacatggaa cttgcagaag
     9181 atatgataaa atatgttata agctatgtat tagaaaatgc tcctgaagaa atggaatttt
     9241 ttaatagttt tatagataaa ggattgttag aaaggttaaa taagatagta aactctgagt
     9301 ttattagaat aacgtatact aaagcagtgg aattattaat tgaatctggg catgaatttg
     9361 agtatcctgt tgagtgggga tgtgaccttc aaactgagca tgaaagatat ataacggagc
     9421 aaatatataa ttgtccagtg tttgttacag attatccaaa agatataaaa gctttctata
     9481 tgagaatgaa tgaagatggt aaaactgtta gagcaatgga tttactagtt cctggagttg
     9541 gagaaatcgt aggaggttct caaagagaag aaagagaaga tgtattgtta gatagaatta
     9601 atgaaatggg attaagagaa gaagattatt ggtggtattt agaacttaga aagtttggta
     9661 ctgctactca ctctggattt ggtcttggat ttgaaagaat aattatgtat atgacaggta
     9721 tgtctaacat aagagacgtt atacctttcc caagaactcc taaaaatgct gaattttaat
     9781 aattatatat aataaaactt atataacttt aagtataaac actaaaatga cttgcatatt
     9841 tatctatttt agagatatgc aagttatttt tattgtacta taaatatata atttgattac
     9901 ttttattttg cgatataata cttataggtt tatgtaatag tatgtaacct tttaataaaa
     9961 tgcaacacaa ttacgtccct gttcttttgc agtatataga gccttatcac aattacttat
    10021 aaactcattt aatgttattg tctttccaat tttctttgta taaactccaa tactaacagt
    10081 tacacatttt aaaggaacat catcacgctc aaaattgcag gactctataa tttttcgtaa
    10141 acattctgat ttaagtttag catctgcctc attacagtta aaaatacata taaaaaattc
    10201 ctcaccacca tatcgtatag catgttcatt ttcagaactt gtaaaatcta aaattacttt
    10261 ggcaatattt tgtagacaat agtctccctt ttgatgtcca taattatcat taaattgttt
    10321 aaaataatct atatctatca tcattccagt tataggttct tgatttgcat ggctgattaa
    10381 ttttttttgt agaatatctt caaggtatct acggttgttc attttagtaa ggtcatctgt
    10441 cataactttg tcgttaagta aattatttat atgagatatt tcttcatatt gttgactaat
    10501 taaaagttta tcatagtaag taaatacacg atttctatat agcattgtag aaacaaaaat
    10561 ggcaagggat gttataaaaa atgtgttgac aatattacta aactcattgc ctggtatagt
    10621 ttgaatccca ggtaagaata aattaagaaa caaaaagcat cctccaaaaa ctattactga
    10681 ttctccaaat tttaatactg agaaagctgc agctgctaac ataatataac taaatacact
    10741 taggtcattt ccacctaact ggtcaagtag agtaattaca caaccccata ggcagaaaaa
    10801 agtcacataa attatccata aatttatata aaacgtacag caatcctttt ttttattcca
    10861 aaggtaagaa aatacaaaca taaagacaga agatacacaa aatagtgtta catacatata
    10921 aaaataccat tggcgtcttg gtgtgacaaa agggcctcct tctctagctg agattgatat
    10981 catcataatt atttgagata ttactattat tatgcaaatg attttacccg tatgataaag
    11041 ataattgcag agttctttct caacattgtc tttgtgtttt ttgtctagag gaaatccaaa
    11101 aaattttttt attttttcta agttcatata agcctccatt aaaaataaag cataaaaata
    11161 agtattcctt tctatcatta gatatttgga atacttcgtt tatgatttaa ttatatcaaa
    11221 atatattgtg tgtaacaatc taaaattgtg atagataaaa tttattagat aatgtcgagt
    11281 aactttattg attaatactt tattataatt aagatttaca gatagtttac tactgaaaat
    11341 aaagaataga ataaatttaa attaagcata ataaaatata aataataaag ttcgcattaa
    11401 caaactattt aaatatcaag acctgttaaa aaacaacagc aataaacaaa taaaatagat
    11461 aaatatatcc aattaaggta taattaagtt ttatatgata tagttatatt tgataattta
    11521 caatagtaaa acttggaggg aaaaaatggg tgaaaagaaa ataaataata tgaattattc
    11581 acataataat tattccaaaa agacaggtga accaactaga aaaataaaaa atagccatat
    11641 cactcttaaa agtaaagaag aaaaaatttg ttctagttgc aataaagaaa ataatactaa
    11701 ggataattac tgtaaatttt gtggaaatga actttatgaa atagcatcat taagaccact
    11761 tgaaacaaaa ctagacttga aatctaaaat aaaagagctt tcatatcatg caaataaaag
    11821 aggtgtattt ttaacaacat ttacaaccat atttatattg tttattattg cattgatatt
    11881 taaagctatt ataactattc aatttaatga tattagttat ttagtaaatc cagcacatat
    11941 aatcctagct ctcaacttgg gtcaaattag tgtatctatg tctaccatga tgggttctgg
    12001 gtttataaat gccaatatag gtttgttgat attacttata atccctattt tggtattatt
    12061 aatatcaaac ctaattttta tgagaaaaag atgtagagat tcaaaaactg tattagcaaa
    12121 ttctctagga gttggaattt tttatggatt agttttagct attttatcta tttttactaa
    12181 tgtaaaaact agttcacata gtatgttaga atatggatat gcattagaat atagttatga
    12241 attttttagt gttcttttaa atggattcgt attagggttt atatgtacat acataactac
    12301 ttataaaaaa agttatgaaa aagaaaatat gtatttatct cttttttcaa attctataag
    12361 aacattcata ttaggttatg ttttagtatt agtaatacta ttggtactaa ctatatctga
    12421 tagtagttac ttaaatgaac tagatatgag tagttattca aatggattaa atttatttac
    12481 tatactccca caaatagcta gttatatgtg ggcttttgca aatggaattt cagtaaccat
    12541 aataaactca acagtatcaa tgtttacttt aagttcttca tctttatttg gagatactaa
    12601 attaatgttt tatgcaatgg gagcattgtc tatgttaata ttattattaa atggatacaa
    12661 gctaagattt aagtataata cagatagtat aagacctata atagtattta gtatatatta
    12721 tgcatttttg atgggaatat tggccttatt tagtacattt atactagata gtaatattaa
    12781 tttctttaat acaactaatt atggaacaac tttaataatg caatttaaag tcttacaagc
    12841 tattgtaatt tcatttgtat atagttttgt gatatcttta ataggatata agctaaattc
    12901 agctgattaa atatgattgg agggaatttc tgtggaagga aatactaata ataaagtaga
    12961 tgataaattt tctaaggtta agaaaaagtt tggtagtgga aaatttaaag ttgaattata
    13021 taaagaaaaa tcaaaattaa atagagagat tgatgatatt caagaaaaga aagcaaagat
    13081 attcttggaa atgggaatac tgacatatca aaaaattaga gaagattcta ttaatgataa
    13141 tagttttgat aaattctgtg atgagttact agaacttgat aagttaattt atgaaaaaaa
    13201 tatggaaatt aatgaaatgg aaatggcaga aagtaatgta acttgtgagt gtggttatgt
    13261 tggaaatgta aatgataaat attgtgctga atgtggtaaa aaatttgaat tggaaaatga
    13321 atgtgatgat tttataattt gtggttattg tgaaagtgag atagatacag aggctgaatt
    13381 ttgtccatgc tgtggaagaa aaattataat ggatttagaa taatattggg aaacctatgt
    13441 atagtataca tgggtttttt tattgaaatt atttaaatgg acttataaca gtagttatat
    13501 aaaatgaaaa taaacaccaa aaaaatgaaa taaaatttct tttaaatgta aaaaacaagc
    13561 taatatataa aataaatcag taaaaatata gatgcgagaa aaaatatgaa aaaatattgc
    13621 aaagaaaaag ttttcatgtt attattaata cataaatcaa gaaaataaat ttcagaaacg
    13681 aggtaattta aaaaatgcta gataaggtaa agggaagatt aatagtatca tgccaagctt
    13741 tagaaaatga acctcttcat agtcctttta taatggggag aatggctaag gctgctatgg
    13801 aaggtggagc tgttggaatt agagctcaag gagttgaaga tattattgaa ataaaaaaag
    13861 ttactggact tcctgttata ggtattataa agagaaacta tgaagattca gatatatata
    13921 taacgccaac taaaaaagaa gttgatgaac ttttaacaac agggtgtgaa atgatagcat
    13981 tagatgctac caatagagtt agaccaaata atgaagactt aaaagaactt ataaagtata
    14041 taaaagaaaa cggtgttcta gtaatggcag atatttcaaa ttatgatgag gctatcaaag
    14101 cacaagagta cggtgtagat tgcgtttcaa ctacactatc tggatatact ccatatacta
    14161 aaacattaga aggtccagat tttgtattaa tgaaaagatt agttaaagat ttagaaatac
    14221 ctgtaatagc tgaaggaaag gtaaatactc ctcaagattt aaaaaaggtc tttgagttgg
    14281 gtgttcattc atcagtagta ggttcagcaa taacaagacc acaattaata acagaaaaat
    14341 ttgttaaagc aattgaaatt aattaaaaat taatttataa attaaaaaat tattatattt
    14401 aactatattt gaaaattaaa attggaggta aagatatgag aacaacagat atgaagggaa
    14461 tttattcagc attattagtt tcatttgata aggaaggaaa tataaatgaa aaagggttaa
    14521 gacaaataat tagacacaat atagatgttt gtaaagtaga tggtctttat gtaggaggaa
    14581 gtacagggga aaacttcatg ctttcaactg atgaaaagaa aagaatattt gaaatagcta
    14641 aagatgaagt gaaagaagaa ataaaattaa tagctcaagt tggttcagtt aatttaaaag
    14701 aagctgtaga acttgctaaa tttacaactg atttaggata tgatgcaata agtgctgtta
    14761 caccttttta ctataaattt gattttgaag aaataaaaca ctattataat acaataataa
    14821 attctgtaga taatagatta ataatatact ctataccatt tttaactggt gttgatatga
    14881 gtttagacca gtttggagaa ttatttgaaa atgaaaaaat aataggtgtt aagtttacag
    14941 cagcagattt ctacttatta gagagaatga gaaaaacatt cccaaataaa ttaatatttg
    15001 caggatttga tgaaatgatg ttaccagcta cagttttagg tgtagatggg gcaattggtt
    15061 ctacattcaa tgtaaacggt gtcagagcta gacaaatatt cgaattaact aagaatgaaa
    15121 aaatatcaga agcacttgaa gtacaacatg tgactaatga tttaataaca gatatattag
    15181 gaaatggctt atatcaaaca attaaattac tacttgaaga acaaggtgtt gaggctggat
    15241 actgtagaca acctatgaaa gaagcaactg atgaaatgaa atcaagagca aaagaaatat
    15301 acagaaagta tttttaataa aatactttta gtatgggagg attagtcaaa tggtaggatt
    15361 tacttggata gattttgcaa tactagtggt ttacttattg gcagttttat ttgcaggatt
    15421 gttattttca aaaaaggaaa tgaagggaaa agagttcttc aaaggtgatg gaactattcc
    15481 gtggtgggtt acatcagtat caatatttgc cacattatta agtccaatat catttttatc
    15541 attagcagga aattcttatg gtggtacttg gattttgtgg tttgcacaat taggtatgtt
    15601 tatagcaata cctttgacaa taaaattttt cttacctcta tatagtaggt tagaaataga
    15661 tacagcatat gaatacttag aaatgagata cgaaagtaaa ggtcttagag tacttggagc
    15721 tttgatgttt ataatatatc aaataggacg tatgtctatt ataatgtatc ttccatcaat
    15781 agttctggct ggtcttacag gaatacctgt aaatgtactg ataatagtta tgggtgtaat
    15841 agcaataatt tactcatata caggtggatt aaaggctgtc ttgtggaccg attttataca
    15901 aggaatggta ttaatagtag gtgttacagg gacattgttc tatttaatag caagtataaa
    15961 tggtggtttt ggaacagtaa tggatactct tacaactgga cacaagttct tagcaagtaa
    16021 tgaagttatg tttgataaaa atatactatc tacaagtgca tttataatat ttgttggagc
    16081 tggtcttaat actttttcat catatgtatc gagtcaagat atagttcaaa ggtttactac
    16141 aacaactgat ataaagcaac ttaataaaat gacatatgga aatggtgttt tatcaatggg
    16201 acttgcaaca gtattttatc taattggaac ttgtttattt atatactata ctcaaaaccc
    16261 agatttagct caaacagttc aacaagacca agtatttgca tcatatatag cttatgaatt
    16321 accagtgggt ataacaggaa tactacttgc agcgatatat gcagcttctc aatcaacttt
    16381 atcgacaggg cttaattcag ttgctacaag ttggacttta gatatacaaa ctatcataac
    16441 aaaagatata agtatggaaa agcaaactaa gatagcacaa tatatatcat taggtgtagg
    16501 tatactttct atagctgttg caatagtatt agcaaatgga gaaataaagt cagcatatga
    16561 atggttcaat agttttatgg ggctagtact aggtgtttta gcaggaatat ttgtacttgg
    16621 tgcattttgt aaaaaagcaa ctaaaatggg agcatatgtt ggattcatag tatcagcaat
    16681 tttagttgtt tatttaaaat accgtatgcc agaagtaact tcttgggcat attctctaat
    16741 aacaatcacg acttctgtag tggtaggtac aatagttagt gcaatagaag ctaaagttaa
    16801 agcaaaagta tctttaccaa aagctgagac tactgtttat tatgaaaaat aatatttaaa
    16861 tgataaattg tcttatagag tgattagata aataatttag ttactctata agattgtata
    16921 atatactttg tatacaaaag tataaaaata gactttataa ttatataggg agatagtgct
    16981 tatgatattt ggaaatataa atcatagtaa gacatattca acattgcatg aagatttact
    17041 tagatgtttt gaatatgcta aagataattc attaatagat tatgaaaaag gtacttatac
    17101 aatagatggt gatgatattt ttgtgaatat tgtagagtat aaaacttgtg aaaaagaaga
    17161 tagattctgg gaagctcata agaagtatat agatgttcat ttgatgcttg atggatgtga
    17221 acgaatagat ataaatttta tagaaaattt agaacaaaaa atatatgaag aaaagggcga
    17281 tttcttgcct cttgatggta aaaataatgg atacatggaa cttagaaaag gtgatttttt
    17341 agtttgttat ccggaagatg ctcatatgac aggaataaaa gttttagaaa aagaaaatat
    17401 caaaaaagct atttttaagg ttttggttag ataatgataa tttatataac cactagggct
    17461 gaaaatagtg atttaacttt cagcgattag tgagacttcg taaattttag ttagattact
    17521 attttcagcc ttagtttttt atgagaaaat taaaaataat taaaagctta aaattttgta
    17581 aaggagttaa cttatggaaa atatagatgt attcttatta ataggacaaa gcaatgctag
    17641 aggattggga aatccaaaag agagcatcat tccaaatgaa aattgttttg aatatttgag
    17701 tactgatgaa attataaata tgagatgtga gctagagact tcagaaggtg atggtactat
    17761 agcacctgca ttttcaaatg aatggaataa gcttactgga aataaagttt gttttattca
    17821 caatgcaaaa gatggttcaa gaataaaaaa ctggaatcat gataataact ggtttctaaa
    17881 tgacactata gaaaaattta atacaggctg tactacctta agtaaacatt ataatataga
    17941 aaataaatac gttatttgga ttcaaggtga aagtgatgca aaatatggta gtgatgtatt
    18001 gtactataaa gaaagtctaa aaaaaattgc gtataggctt aaagaagaat gtatgattga
    18061 taaaatgttt gtaagtttaa ctggttattg gcttggagaa gatgaatatt ttattagaac
    18121 aagacgaatt gcagcagcac aggagtcggc ttgtagtgaa tgtgatatat tatgtgtagg
    18181 aagcaaaatt gctatgcagt ttcatgacag aggattaact attgatgatg ttcattacac
    18241 tcaagaaggt cttaatatgt taggagagga cttatgtaaa aatatttata agtatcatat
    18301 aaccaaagaa aaaagtgtat taagtgatac tatagactta tcagaagcaa ggaaatatat
    18361 ctgtgaattg gaaaagataa gtaaaagatt tgtgtaatat aaaattttaa atagagttgt
    18421 taatttataa aaataatttg tatggagata tgttatgaaa aattacgttt gtatagatgt
    18481 tggaggtact tcaataaaat atggttttat tagagaagat ggatttataa ttgataaatc
    18541 aagtcttgat actgaagcaa aggaaaaagg tggagaagga atattagcca aaataaaaga
    18601 tatagtaaaa aaatatatag aggaaaatga aataagtggt atatgtatat caactgcagg
    18661 tatggttgac ccagttgaag gtaaaatact atttgcatta gaagaattaa ttccaaacta
    18721 taaggacatg caattaaaaa aagaagtaga aaaagagttt aatataaaat gtgaagttga
    18781 aaatgatgtt aattgtgctg gacttggtga aatgtggctt ggagcaggta gaggtgcaac
    18841 atcttctata tgtttaacaa taggtactgg aattggtgga tgtattataa taaataataa
    18901 actgataaat gggtttagta atagtgctgg tgaagtagga tatatgaatg taaatggaag
    18961 ttcttttcaa gaattggcat ctactagcag tctaattaaa aaagtagcaa aaataaaaaa
    19021 tttgaatgaa aatgacttaa atggaaaaat aatttttgat ttagcaaaga ataatgatga
    19081 agattgttta aaagaactcg ataatatgat aaaatcatta gcagttggaa tcgcaaatat
    19141 atgttatgta ataaatccag aagtggtaat tttaggtggt gggattatgg cacaagaaaa
    19201 gttcctaaaa ccaaaaatag acaaagcatt aaaggaggtt cttatagaga gagtttacaa
    19261 aaacactaat atagaatttg caaagagaca aaatgatgca ggaatgcttg gagcattata
    19321 taatttttta aacaaaatat aaagaataga agggttttta atgagtattt tagaacaatt
    19381 ggaatcacca acttttaaag tcacaaaatc agataaatta ttaatagctt atataaaaga
    19441 aaatatagat gatgtatttt ataaaccaat atcacaaata gctaaagaga gcaatattgg
    19501 tgaagcaact ataactaggt ttgtaaaaaa aatgaatttt aatggattac aggattttaa
    19561 agttacttta gcacaagaaa tatcaactat caataaaaaa aatattataa ataaaaatat
    19621 acaaaatgat gagccagctt tggatacagc aaaaaaactt ttaagttcaa atgtaaccac
    19681 tttagagaac acagtagaga taatcaatag taaggatgta catgactgcg caaggcttat
    19741 aataaatgca aagaaagttt acttcatagg tattggatat tctggtataa tagcacagga
    19801 ttcaaactat aaatttatga gaataggtct taattgtgta agttttgaca gtagtcatac
    19861 aatgataatg atgtcttcca taatggaaga aggagattta ataattgcaa tttcacattc
    19921 tggtgaaaca gaggagatta taaaaactgt aaagcttgca agagccaata atgctaaaat
    19981 tatatcaatt actgaaaata aaaattctga attaaaggat atttcagatg tacacttatc
    20041 ttatgtatcg ggagaaacag tactggaaac cggttcaata tcttctaaat tagcacaatt
    20101 tttcattatt gatttagtat atacacaggt agtaaaagaa ctttctaatg aagctattga
    20161 aaggaaaatt aaaactacaa atgctataaa attgtttaaa aatgaataaa ataagaaatt
    20221 tgtaatgttt tatagagctc tcttaaaaat ttaggaatgg agagatatta catgtctaaa
    20281 ttaaaagatt ataatattga taaagtaata atttttaata atttaagtac taaaacgaag
    20341 aatcaactta aagaaaaagt taaactaaaa agattacaaa aaaaagaaat tttattttat
    20401 gaaaaagata gcttagacag tgtttatata cttttagaag gaaaggtatc tatttttaag
    20461 ataagtgaaa atggagagag aaaagtaatt ttcatattaa atagtgggga agtcataaat
    20521 gatattacac ttgacgcttc taaaaactct actgttggct gtgaagcatt tgaaaattca
    20581 attgtagctt attatagtat tgaagaattt ttagaaatta tgcaaaatga ttttcaactt
    20641 acaaaggata ttatttctta tatggaaaga agaataagac gtttatatag acagttgaaa
    20701 aattctatat ctataaaagt agataaaaaa cttgcagcaa aattatatag gttaagtaga
    20761 gaatttggag tttgctgtgg agaatggact ttactaaatg taaatattac agttacatat
    20821 ttagctgata tgcttggctg taaaagggag actgtttcca gaatgataaa ggtattgcaa
    20881 aaagaagaac ttattaaaat tgacaataaa ggtttttatg ttaaagaaac tgaattatca
    20941 aggtatttta aaaataatta attatgatta agtaagagta ttattagaat tttaattaaa
    21001 taaaaatatt attaagagaa tctatttata gattcttttt tattgtctaa tttattaatt
    21061 tttattttac cctattgaat tgtataaaaa aacaaataag attctttttt attcaaaaaa
    21121 cttactaaat ttttgattat cttttcataa gttggtaaat gccgatatat cccgtatttg
    21181 agggctttat cggtattttc tttttggaag ataccttgca taagctggca tttaccagca
    21241 tgaaaatgca accaaaagta gtaaatgagt agtaaatata cgttccgata ttaacaagcc
    21301 agtctttcca gttctgcttt tgcagattgg aatgtaccgt gtgcgtagta gccaagcgtc
    21361 atggttatgt tagcgtgtcc catgagatat tgcagggtgt tcgggttcat tcccttgttt
    21421 gccatattcg tacaataggt atgtcggaat gaatgtggtg taatgtttgg taacttgtct
    21481 ttgtggtatt tgttatactt cttaatcagt cctcgtacca tacccacata gtttccagcg
    21541 actttaggca atccctcacg gtttaagaat aggaaattgc tgtaaccacc aacaaccagc
    21601 ggttgagctt ttactctgtt ctttagtatt ctttggagtg cttgataagc cctttccgtc
    21661 aatggaattt ttcgttttcc gttctttgtt tttggagtgt caatatagta gccgatttcg
    21721 ctatctctta atagctggtg gtctatattg agtattctgt tctgcatatc aatatgcgtt
    21781 gtcagtccgc aaaattcaga aatacgaagt cccgtttcca gaagaagcac aacctcatca
    21841 taatacttgc tgtaaatctt atccgtttcc ataaaggcaa gcaggcgttc ttcctgctct
    21901 ggcgtaagaa taactttcgg ctcggtatca tcttccagaa catcacttag cttaaattca
    21961 aacgggttct ttctgataca gtcgtcttgt atcgccatat aaaatgacgc tttcaaggaa
    22021 cgcttatagt tgtcaatcgt tttgtaggca tatcctcttt cactcattct gatagcccac
    22081 tctttagcgt ccgactgttt gacggtatca atcgctctca tacccaatgg gtcatttttc
    22141 agagcgttca taagatactg tcgtcctttt tccgtagctc gcttgatgtt ctttctttgg
    22201 ctgttcttct tgtcgtaaag ctggcagact gtcattttac cgcctgccgt gtcaataccg
    22261 tcatcaaggt ctttttttat ctgtgcttct ttttccctca acgatatatc atcacgtttt
    22321 ccagcaggcg ttttgtctgt cggtacaagt ttccaagcat aaataaactg tggctttccg
    22381 tatatatcgg tatatttata aacgtatctt ccgtcttttc gctggctctc tccattacgc
    22441 aaattgcgat ttttactgtc ttttcgtttc acattagaca tagtgtaaag ctcctttccg
    22501 tcatggaatg agccgtgata cgctatactt attataccat atccacggct ctatgacatt
    22561 agatttcgtc caatgtatct atgatttttt caaattgttt tcgctttatc tgaatacggt
    22621 tgccgttcac gataacccag ccagcgtcaa tattttcttc ggctaattta cgcaacttct
    22681 tttctccaat gcggaagtat ttggacgctt cttcaatcgt cagtgtatat ttttcccaga
    22741 taggcacatc agtattattc ataatttatg cacccccttt actgtgtgtc agtctataag
    22801 ttatataaac aggcagacgg ctttggaaag ctccattagt atttcaacta ttcccattct
    22861 tgtgggcaga accgcaccat gcggaagtat cattatgctg taagggtagg tcatggcaaa
    22921 acgacttttc caacggtcgc tctcggatca ctgcgtgggt cgctcgcttt cttttggaaa
    22981 ggtcatggcg tacagttccc gtggctctct atccttacaa acgtatctgt ctgctttatt
    23041 cagttttcaa agagctgtgg cgaaagcggt atgctttcat gtaaaagcag gagcagagca
    23101 ggaaagaggg gattgaacaa atcatgctct gcgttactgc tggttattct tcttcaattt
    23161 ctaaggcaat atcaaaccct aaaatcattt tgataagtgc ttctcggata agtcctttta
    23221 actccatatc tacaacgata taaacattac cgtattcatc atagagtgga cgcaaacagc
    23281 acttcgatat gtaagggtca taaaatgcaa gtaccttttc aatcgctttt tcgtccccgt
    23341 ccatagcttg tgaaagcaag tagtaagacg gcttcttaaa tgtgtgtttc atttgctatc
    23401 gtttctcctt taatagtttt ctcataagtg ccaatgaatt gtggcggttc tgaaaaactc
    23461 cgcttctgga aatgttttgc tttttggcga tttcttcatt gttcatttcc aaaaagtaat
    23521 acatcaacaa agtttctcgg ttacgttcgg ataactgttt caaggcttct gccaattcat
    23581 catcatagac acgaatatca ttaccgcata cattgaaaat cgtatagtct gtttcgtagt
    23641 cgtcccatac agccaagttt tcaaccatga tttctggaag ttcacaaaag gaaatttctt
    23701 tttcttttct tcgcttcaat ccctgctgat agtccttgac aacatgacgg acaactttct
    23761 tcaaacagct ttcaaaacgg cattgaacag ttttctggaa gtcagacggt ttcatcaatc
    23821 tcaccccctt tccgttatga cgtgaaaagt gtttatccct ctttccgcac catataggga
    23881 atggcaagtg tgatttgtta agttgaaacc agaaaaaatc gaaaaaactt tttagtaaaa
    23941 caaaaacagc ccgtgtgaat gtgaatacac aaacggactg ctttataaat gctatctgta
    24001 tgaattttta actcttgtag agggtagaat gattgtaata ctgaactaaa atattttttc
    24061 agttgggaac agcaaagtat tattccatat acaatcatgg cgtagccccc tttaccagag
    24121 ctataccttg tgccaccaat gaaaaaggac ggctctggct atatccaaaa ccgccccgtt
    24181 atgttttcaa gacgcacaaa agtatatcat ctcggaacgg ttatggtgat ttaaaatgag
    24241 aaaaacaaaa gaaacacata cttttgattt cagaccgcta gggctggcaa tcagagaagc
    24301 ccgtgaaaaa gctgggcttt ctcgtaatga tttaggcgat aaggtattct atggggaacg
    24361 ccatatcgca gatattgaaa atatcggttc acacccaagt tttcaattat tccatgattt
    24421 agttaccatg ttcaatatat cggttgatga atatttctat ccagcagaga aagttgcaaa
    24481 aagcacagct cgccgtcaga tagaaacatc acttgattta ttgagtgata acgaattaaa
    24541 aattattcaa ggtacgattg acggtatctt gaacagcagg gagaataaga agtaatcagc
    24601 ttcttgtttt ccccgttttc tttttagcca tatttcttca agacttattt gttgatctgc
    24661 tttgcaggaa acaaataaga gccgacaatc tataagttac aataacctac aaattatcgg
    24721 ctctgcgtct tagcgtctgg ctctttgata atagttactt ttccatgctt tatattgatt
    24781 aaagtttccg ttttgcactt cggacagaac aaaggaaaat ttatcaattc cgtatcttct
    24841 cgcactttag ttcgtgtctt attattgcaa ataggacata atacccacat ttcatttttc
    24901 acagaaccac ccttactaat tctttaaact cgtgttttct tcgtgatttt atagatatat
    24961 tcctctggtg tagggcgttt atttccaaaa tactttttga aatttgcctg cacttctggg
    25021 tcggtgctgt tcataacttc atcaatcgtt gcttcaatat cagccaaaac atcagcatac
    25081 gaagaaccac cagcctttgc accagctttc aatgcttttt taatatctcg ttttttaatt
    25141 cctatcacaa gaaccaactc cctaaaatac gttaatcttc tttttcaaaa attaaatcta
    25201 tctttcgcat acagcctttt gcgtcaattt ctgtaggcac gaacccgcat agcgataccc
    25261 attttctgca tagctattta taacttcctt atgtttatcg gtgcaaagga atacaacacc
    25321 tttcgcagta taatcaattt ctaaatattc atattttttc atttttcctt tctttttcat
    25381 attttatctg tattttttga ttgccttatt tcttaaagga atacccacac ccaatatcaa
    25441 tactactacc aaaatagata aatccataag cacacctcac ttttctaaaa ttcttttttc
    25501 ttcattattg ccagactaat aaaaattgtc atatccccat accttttcat aaatctgttc
    25561 ttttgtgaac acctgtcctt tgtggctgga aaggaaatat agtaggtcaa attctttagc
    25621 agtcagatat atagacgttc cctcttcgtt ggtaaaggta cgggttaatg ggtctatatc
    25681 aaatcctttt ttctgctgat taaaagaagc aggggtgtaa gcaagtttag aggacagcca
    25741 ttccaccgct tgttggaaaa cagcgtcctc tttttcagta aattcaacaa tcagtatttt
    25801 cccatagtac cacctacctt aaatttatga aaggggaaag agtttactgc cagtgaaata
    25861 ccaatcccta atgaagtgtc aacaatccta ttccatgcga accaaatagg acttatatct
    25921 ttctcatgtg ttactgttac gcataagaat acaacgcacg ttaaaaatgt tccttttttc
    25981 tgtttcaaca gtacagacag attgatgatt ggaatcaata aaatagataa agtcaattcc
    26041 cgaagtattt ctggctgaat gggcaaaaaa attctttcca taagcaaaaa gagcattccc
    26101 agtataccgc cgataattgt tgaaagttcc ctgtttttag caacgctcaa actgttttcc
    26161 atatctggct gtatgcacag tatagacgca atcactgcat aaaaaggaac acttgaagct
    26221 cttaagctat ctatcaaaaa acaaaggaac gcagaaagta ccgtcttaat tgtccgcaat
    26281 ccaactttaa caggcttact tttcatacaa cccttttagt acagcttctt caaggatgtg
    26341 cccctccatt tcttgataga gttcattaag ataaaatccg ttttttaaat caagcagttt
    26401 atcaagggca aatacatgaa gctcataaat atgtgcttta tctggtggtg ccattccacc
    26461 ataacagctt gtctgttctc tggtttgctg attccccaat atgcttgtcc agctattcgc
    26521 accttgtata aagtcctttg ctgtctggct ttcgttttcc tttaattcac ttcttgttag
    26581 attagctcct aaccaatgca cccatataaa acccgtcact ggatatgcgt ctttatcttc
    26641 cagtataaag gcaaaggaaa ccgttttatc tggtgcattt tcaattttga acggaattga
    26701 atacgttggc acatcatttt cattgaattg cactccatga ctaccatatt ttttttcaat
    26761 aattccatta gaaattccta tacttgaaat atacataaat tttcctcctt gtatatcgtt
    26821 taattacaga tatatattaa caaagaggaa gcaaaacgta aattacccac ttttttgtag
    26881 gtattagtct ggaatcacgt gtttctcagt taattcattt tccattccat ttttccttaa
    26941 atattcaatc cctatatgtt gcataattcg taatgcttct agtatttgat ttcccatatc
    27001 ttccgtcaaa aaatactcga catgaagtgg ataaccagaa aatgtttttt tatcaacaaa
    27061 tccataatct ataagttcct ttaaatgttc caaaagcatt ttttgtgtaa ttccatcaat
    27121 atcattctct aatttagata atgaagtagc acctaatcgt aagcgccata aaataattgg
    27181 cttccatttt ccctttatca tatcatgaat taattccaaa ggacatgtat attcatctcg
    27241 taatttcatt tgacaaaaac tccgtgcttg taataacatt agcaaatttc tgatttaaag
    27301 aagccataaa tatgctttga actgtatctg ctgggatatt gactccattc cattttaatt
    27361 ccttggtcgc acaaccattt gatattagtg taatctcata gccataatct ttggcagctc
    27421 ttatagttgt gtcaatacac atatgtgtca tcattccaca aacaaccaat ttcgttacct
    27481 caatctctac cagtttgttt tgcaaattcg tttcataaaa actatttgga taatgtttaa
    27541 caataactgt ttctgtatct aatggtttaa tatcattatg gatttgtaca ccatttgtat
    27601 ttggattaaa aaatgttcca tggatagact catggcgaat gtaaataatt ggcaagtttt
    27661 gctttctaaa aattttcaat aaatctttta ttgtattcaa cgcaatctct ggtttataca
    27721 actggcactt tccattagga aaataatcat tctgcacatc aataataagt aatgcttttt
    27781 tcatactctc atatcctctc ttaattctaa ttaaataata taagataata gtttctaagt
    27841 aaattactta ctttttcgtg tatatgatag agtttaataa caaattcctt tttcatcaag
    27901 gatttctgtc ataccatgct ctaccatgta atctatacca atttcttgca ttatcttaat
    27961 tgctgatagc atcttttctc cctgtccagt taaaaagtat tctactttta gaggatatcc
    28021 atcatatgtt tttttatcaa ttaagccaaa gtgttttaat tcacgcagtt gttccaatag
    28081 cattttttga gtaattcctg ctatactgtg atggagttcg gaaaaagagc attttccatt
    28141 tctaagttga aaaataatta tcgttttcca ttttcccttt ataatatcat gaacaagttc
    28201 taatggacat gtatagcttt ctctaagttt cattttatca tctcctatgt gaaatatctt
    28261 acatgtttaa gctcaatatt tcaaaacata ttttattacc ctaatatatg cacttttaac
    28321 acattctaaa tacgaaccat gaagtataaa ctcatgtatg gtgatttaaa atgagaaaaa
    28381 caaaagaaac acatactttt gatttcagac cgctagggct ggcaatcaga gaagcccgtg
    28441 aaaaagctgg gctttctcgt aatgatttag gcgataaggt attctatggg gaatgccata
    28501 tcgcagatat tgaaaatatc ggttcacacc caagttttca attattccat gatttagtta
    28561 ccatgttcaa tatatcggtt gatgaatatt tctatccagc agagaaagtt gcaaaaagca
    28621 cagctcgccg tcagatagaa acatcacttg atttattgag tgataacgaa ttaaaaatta
    28681 ttcaaggtac gattgacggt atcttgaaca gcagggagaa taagaagtaa tcagcttctt
    28741 gttttccccg ttttcttttt agccatattt cttcaagact tatttgttga tctgctttgc
    28801 aggaaacaaa taagagccga caatctataa gttacaataa cctacaaatt atcggctctg
    28861 cgtcttagcg tctggctctt tgataatagt tacttttcca tgctttatat tgatta
//
LOCUS       DAEPKC010000047        28388 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.047, whole genome shotgun sequence.
ACCESSION   DAEPKC010000047 DAEPKC010000000
VERSION     DAEPKC010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 28388)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28388)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28388
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.047"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            266..970
                     /locus_tag="KR294_002076"
     CDS             266..970
                     /locus_tag="KR294_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0240154.1"
                     /translation="MSKLIYIADDEDNIRNLVKTFLKNEGHDVMDFKTGDELLEQFNI
                     KECDLVILDIMMPGSSGFEVCTKLREKSTVPIIMLTARDTDIDYITGITLGSDDYFTK
                     PFSPMSLVMRVKSIFRRIEFEKKQNYDKYSNSIDMELKFGDVIINKKNKIVTSKNVNI
                     DLTPNEYNLLTYLFENIDRAISRDELLNKIWGYDIEVETRAADDTVKRLRKKILDTNI
                     LIETVWGFGFRLKEKS"
     gene            972..2459
                     /locus_tag="KR294_002077"
     CDS             972..2459
                     /locus_tag="KR294_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH0240155.1"
                     /translation="MKNGNDKNRIGKIKSKFKLKFSKKNISIKTRILLSILCLIIIVF
                     MIILVSFNVFLDTYIKTTANEELTKSTEIVEHMDSNFRPIKPPQDDGKLPPKVLSNFM
                     RNVQDKVRMAETQSDADAMVVDSKYNLIFPTREDDFLKNVDEMELIRECIQNEKLDLN
                     SDANTRISTRNKDYYISTVKITSIYGEQDKYLILFIDISKTLNLAQKINIVLISVMCF
                     AGILAIFTAVILSEKIAKPIKELCEFAKKMGQGDFKRTYFDFSDKELVELSTVMNKSA
                     EYLDKYDNEQKIFFQNASHELRTPLMSIKGYAEAIKYNVIDSKHASDIILEESDRLSD
                     MVEDLLYISKIDNITKDFELVECDLREVLSNCGARQNVRAINKGIKFIYEFDEEMVLF
                     ECDEKNISKAFMNLIENALRYAKSEIKIVCKYNQKNIVVIIEDDGIGIKKEDLPHVFE
                     RFYKGVGGNHGIGLSIVKSIVNKHGGRIYVENGKKGAKFTILFKL"
     gene            2664..4277
                     /locus_tag="KR294_002078"
     CDS             2664..4277
                     /locus_tag="KR294_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HBH0240156.1"
                     /translation="MKEQLIFNITNLVTVVFEAFVIHMFLSDFLGQKEGYIKVVRYAK
                     LGFIICLGFCNLITLNPKITMPLIFILIFSTSFLYKGNLKTRLFTTVLLSIFFILSEI
                     VVTSIFVLFVKEGFEIMLENNSIRVLATILSKIVFLLTCKIICLFKKDVHLDMPIKYW
                     LPLFLIPIFSLFLSVSIFDVSKFFSLESLKFLSLISSVGILYINFIVFYLFKFIIDKT
                     KLSMKYELLEKEIIHKEELRLSNECYKIIVEQTDSVVFEWNIKENKSFVSQAWTEKFG
                     YNNACKNIFKEIKDKDLVHSEDKAIFEGFLESIKKKNMHNQAVYRLKKSNGEYIWCRT
                     SITSIYNDENELLRVVGVIVDVDSDIKKYEELRTRAESDSLTNIYNKGTFEKLVEETI
                     VMNTGDKKDALFIIDLDDFKEINDNFGHPFGDFVLKTFADKIQTSFGSKDLVGRIGGD
                     EFVVYMQDYVTEVNLHKKAKELNRVLSDNYTDLSFSFDASVSIGIARYPQDGTSFFEL
                     FKNADRALYSIKASGKNSYCLFEEELYVQ"
     gene            complement(4640..5470)
                     /locus_tag="KR294_002079"
     CDS             complement(4640..5470)
                     /locus_tag="KR294_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH0240157.1"
                     /translation="MSQVSKNYFTTGEFAKICGINKKTLFHYDDIGLFSPELKKENGY
                     RYYSYHQLSIFGIISSLREVKMPLKEIKAYIDKRTPNLLIELLEKKTIDIKNEIEKLN
                     NIQALMESTISFTKNACNIDANTITLKEHEEEYLVKTPVTYKEQFLGDEEENFLYECI
                     NFMDNYELSDYGTIGSIIKGEDIINKDFESYSYLFTKVNKEYKKYPVSIKPKGLYVTA
                     YHKGSYETIYKAYEKLLNFFNQNNLRIGDFVYEEYLLYDISVRDSNEYLTQISAEVKM
                     "
     gene            5543..7270
                     /locus_tag="KR294_002080"
     CDS             5543..7270
                     /locus_tag="KR294_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0240158.1"
                     /translation="MKKLIHFLKPYRVLIVVVLIFTFLQTLGTLYIPTLTANIVNNGV
                     VKGDIDYIVKTGLMMMIVAGITALSAVLVCKVSANLSSGFCRDIREAVFIKSQDLSIN
                     DFNNIGTASMITRSTSDITLIGQSVFMFIQLVLPAPIITVSGLFLAYSIDKAMTIIIV
                     VVMFLFMLSAFLVGKKLIKLFKMMQIKMDNMNRVLREVVTGVRVIRAFNRSHFEKKRF
                     DRTAIDYSETAISINKIFAVLMPIVMLIMNLGIVSIIWFGGMRVSNGNMEIGHIMALV
                     EYCILILFYLIMGVMVFMYIPRAGACADRVNQILDIEPEIVDGNGHKDTVSERGHLVF
                     KNVTFSYAQSEEPVLNNITFEAKSGEVTAIIGSTGSGKSTIANIIPRFFEIQSGEISI
                     NGQDIKKIPQKELRDKIGFVPQKAFLFSGTIEENIRYGKEDASIEEVKHAASIAQADE
                     FISDMEDKYDSFVAQGGNNLSGGQKQRISIARALVRKPEVYVFDDSFSALDFKTDKRL
                     RKALKNEIKDSSAIIIAQRISTIMDANQIIVLNDGKIVGIGKHKDLLENCEVYKQIAD
                     SQLSKEELA"
     gene            7307..9169
                     /locus_tag="KR294_002081"
     CDS             7307..9169
                     /locus_tag="KR294_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0240159.1"
                     /translation="MSEKRIDEQDIEVLSFEDGMSAEKAKDAKKTTKRLLKYMAKQKF
                     KILIIFISVLISSALTVLAPMVMGKAIDQLFNGIKTAVQTGTKFSVNFSTMGGIVSIL
                     LGLYLISAVFIYIQQYIMSGVAQNLVLSMRKDLSDKLNKLPLKYYDSHKKGETLSIVT
                     NDLEKVADSLQEGLMQLITAVVTVVGSIVMMISISVPLTIVSAITLLVSLGITVVIAR
                     KSQERFSENQKALGELNSNIEEIFTGQIVVKAFSKEKDTIRNFKILNQNLYNASRKAQ
                     FSSYAISPIIRFINLIGYVIIAVVGGIFASTGAMTLGSIQAFIQYVNQASEPTTEISY
                     IVNMLQAAIASAERVFTVMDEVEEIKDEESSKVISMPKGKVQFEHVKFGYSDDFILMK
                     DININLNAGDKIAIVGPTGAGKTTLVNLLMRFYEIQGGRITIDGVNIKDLKRGELRTM
                     FGMVLQDTWLFNGSIKENIAYSKSDATMDEIVRAAKSARVDHFIRTLPQGYDTILTED
                     ASNLSQGQKQLLTIARAILSDPSVLILDEATSSVDTRTEVEIQKAMNNLMKGRTSFVI
                     AHRLSTIRDADLILVMKEGTIIEQGSHKELIEKKGFYEELYNSQFTSEYDEDVV"
     gene            9502..10191
                     /locus_tag="KR294_002082"
     CDS             9502..10191
                     /locus_tag="KR294_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyphosphate polymerase domain-containing
                     protein"
                     /protein_id="HBH0240160.1"
                     /translation="MNKKLNYRFEMKHKITEADVLALKSRLYQIMKKDENASKDGKYL
                     IRSLYFDTPEDKALLDKLNGVAIREKFRIRFYNNDCSYIRLEKKIKHYNMTSKLSTNL
                     TKKEVINILNNDIEFLKESTNCLLREFYLKLKCERLEAKSIVDYNREAFIYPVGNVRV
                     TIDSDIKTSVNSVDLFNKDLPTVSVIDENMTVLEVKYDEFIPDFIKDLIQINKTTSTA
                     VSKYASSRLYI"
     gene            10296..10982
                     /locus_tag="KR294_002083"
     CDS             10296..10982
                     /locus_tag="KR294_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4956 domain-containing protein"
                     /protein_id="HBH0240161.1"
                     /translation="MILIMTFNDIFKSSFIENVSGFSFVDSALALGSAFLVGLFIYMV
                     YKKTYMGIMYSRPFNVSLVALTMLTTFVILAVTSNVVLSLGMVGALSIVRFRTAIKDP
                     MDLVFLFWSLGSGIVLGAGLIPLAVMGSIIMGLILIFFSNKTISETPYILMVNCNNED
                     SEDIATDKIKKVFTKYQIKSKSVTPEKGIELVFEVRMKDGETSLINDLSQVDGVTNAV
                     LVSYNGDYVA"
     gene            10999..12906
                     /locus_tag="KR294_002084"
     CDS             10999..12906
                     /locus_tag="KR294_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CotH kinase family protein"
                     /protein_id="HBH0240162.1"
                     /translation="MKDKKFTLLISIMIIFLCAVVGVYSTSSNKSVDLYSDVYIEKYF
                     NRDKVMEVNIEIDESDLKDMNENAIKEEFKVAKVTVDGDTYGNVGIRTKGNSSLISVA
                     NSDSDRYSYKINFDKYNTSQSMEGLTQLNLNNCYSDPSYMREFLTYSICEEMGLATPE
                     FAYAKVSINGEYHGLYLAVEGLKESYLENNFGNVTGDLYKSDEGSSLQYKGDDPESYS
                     NLIVESDKKTADWSKITKLLKSLDTGEDIEKYLDVDSVLKNIAINTALLNLDSYQGSF
                     AHNYYLYEQDGVFSMLPWDFNMSFGGFSGFGGGSQSIAIDEPTTGNLEDRPLISSLLK
                     NETYKTKYHKYLEEIVTKYLDSDYLENMTTKLHDMIASYVKEDPTAFYTYEEFEKNIT
                     SSIEDSSDNKGFGNKGFDNNNSNNSDSNNNSNSENKRSGNQSDEKEVNAELTSSVVKA
                     NTDNETKNKTTNDSESKNNTDKDKSGNDNNQKLEGPMGKGGKSIPGVLEVAEDMSKTI
                     KSQLSGETSSTKQNSGDESSSGIKGSEKFDEDMSGMPEPPEGMDGKMPPGMGNMDKGD
                     MNGKNGNMNMDRNQDNPIEVGGFGNRGGGSVSKTTTYFKLILGGASMIIMSIMLVGVS
                     RVKRRRFIKSK"
     gene            13357..14046
                     /locus_tag="KR294_002085"
     CDS             13357..14046
                     /locus_tag="KR294_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240163.1"
                     /translation="MLQKVLWKFLKLVVGLFICSVGIVLTINCNLGLSPWDVFHQGLS
                     NHIGITIGTASIIVGSIVVIADVVLGENVGWGTVFNMLLIGFFMDLLLYSNLIPEADN
                     LFVGIIMLILGLVLLSVGMVFYMGSGLGSGPRDGLMVAIQKKTGKSLKLIRGTIEVGA
                     LIVGFLLGGKVGIGTIISAFGLGYFTQMVFGLFKLDCSKIKHRFIVDDIKFIKVYMSG
                     EKKAAVQNIVK"
     gene            14482..15021
                     /locus_tag="KR294_002086"
     CDS             14482..15021
                     /locus_tag="KR294_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007286148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0240164.1"
                     /translation="MDIGEKIKRLRTEKQLTQEELANRCELSKGFISQLENNLTSPSI
                     ATLIDILEILGTNLREFFNEIDDERISFTKEDMFETEDEDLKYKLKWLIPNSQKNEME
                     PIIITLYPGGQYKEEKPHEGEEFGYVLAGSIYVHIGEKKNKVKKGESFYFRPKANHYI
                     SNEGKTTAKVIWVSTPPSF"
     gene            15040..16083
                     /locus_tag="KR294_002087"
     CDS             15040..16083
                     /locus_tag="KR294_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011721317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0240165.1"
                     /translation="MVENIIELRDISKHYEELTVLDNFNLDIKKNEFLTLLGPSGCGK
                     TTTLKIIAGFEYADDGKVLFEGKEINNLPPYERQVNTVFQKYALFPHMDVYENVAFGL
                     KIKKTPKDVIDAKVKEVLKLVALEGFERRQVESLSGGQQQRIAIARALVNEPKVLLLD
                     EPLGALDLKLRQEMQIELKRIQKKLGITFVFVTHDQEEALTMSDTIVVMYKGKIQQMG
                     TPQDIYNEPKNSFVAKFIGESNIFDGIMIEDYKVNFCNRDFECVDKGFEKNENIEVVI
                     RPEDIKMVKPEEGMLKGKVTSTVFKGVHYEIELNENGRLWILHNTKNAEVGTELGMDI
                     YPEDIHIMRKENN"
     gene            16085..16921
                     /locus_tag="KR294_002088"
     CDS             16085..16921
                     /locus_tag="KR294_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0240166.1"
                     /translation="MKRKSFLAYPYVVWSAIFVIIPLILVVFFSFTKESGGGYAFTLE
                     NYKEVIDPIYMKVFGRSILLAGGATLICLIVGYPVAYIISKARVSRRGSLILLFILPM
                     WMNFLLRTYAWVAILGKNGLLNTFLGWFGIQPLAILYTNFAILLGMVYNFLPFMVLPI
                     YTALSKMDNDLINAAHDLGANNMTVFRKIIFPLSLPGVMSGITMVFMPAVTTFAISRL
                     LGGGKIMLVGDLIEQQFTVVGDWNFGSAISIFMMIVILISMSIMSKFGDESDKEGGGL
                     LF"
     gene            17026..17700
                     /locus_tag="KR294_002089"
     CDS             17026..17700
                     /locus_tag="KR294_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0240167.1"
                     /translation="MARWNGFTWKWYGQLLQNESIMSALYYTIVIAILASVISTIVGT
                     ISAIGIHKMRGKSKKLILNVNYLPILNTEIVTAVALMSLFVFVKMEFGFTTMLLAHIM
                     FCLPYVILSVLPKMKQLPDNIEDAAMDLGATPIYALRKVILPQIKPGIVSGFLIAFTM
                     SIDDFIISFFNAGNGVSNLSIEIYGMARRGIKPEINALSTIMFAVVLGLLLLANKKES
                     IVRGIK"
     gene            17700..18752
                     /locus_tag="KR294_002090"
     CDS             17700..18752
                     /locus_tag="KR294_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter
                     substrate-binding protein"
                     /protein_id="HBH0240168.1"
                     /translation="MIKFKKAISLIAVGMMTVTLFTGCNKATDSTKVLNVYNVGDYID
                     ESLIDKFEKETGIDVQYSTYDTNEMMYQKVKSGSTHYDLVFPSDYMVEKMKNEGLLEK
                     LDFKNIPNMKYLDKSFLNPVYDKTNEYSVAYMWGTLGILYNKKEVKDPMDSWNILWNP
                     KYKGNIMMFDSVRDTIGITLKKLGYSMNSVNPKEINEAKNLLMKQKDLVLAYVNDEGK
                     DRLLGGEVAMGMLYSGDAVTLMEQNPDLDYAIPKEGTNKWVDAMCVPTTAQNKKEAEL
                     FINFLLDPENAKVNAEYIGYSTPNTGALKLLDPEITQNPVAYPSKEVLDKCETFEDIG
                     ENIKLYDKAWIELKSK"
     gene            18982..19830
                     /locus_tag="KR294_002091"
     CDS             18982..19830
                     /locus_tag="KR294_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBH0240169.1"
                     /translation="MNRINKKIDLLILALLVFIFLIVGIVILSIRTENKLNVFIMLAI
                     IFFIIMLTYLSNSVVGLITSSIIIFMYTSYILYNNITHNMDVEFISYMWIIATPVSSI
                     IMGNLNKSINELQNTNKKLSEQYKELVTIDSETGLRNLKIFYNDVNMEISKSIRHNTD
                     FSLMIVKLPYYGNLQTIFGENKTNKIVKYIGSNIIECTRNEDIIYSLQKDMIGILMPN
                     TSLEGSKVVKDRIKKRIKELNLDLNNRGKYVNIDVKIAFLQYKSSFGDSINFKNIVEE
                     ELQYDV"
     gene            19820..21484
                     /locus_tag="KR294_002092"
     CDS             19820..21484
                     /locus_tag="KR294_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBH0240170.1"
                     /translation="MMFKIFNKSLLKLVVVLSIVLTISNFSLSSYASEITSSTDKVLI
                     IYDSKKETAYNRDILNIMRTLLGRFSSDIELLKLSNYDGEINKNYYSHIFILGINENS
                     YNNDKNTKNLISSLNSYKGTICWLGYGIENLLEHKKYNLDYVGKTNNIVSVNYRGKSY
                     NLDEHYVFNIVESKDTSNKVIGSINDTLNKYPYIINDKNLFYVSKLDLDGVLFYIFCD
                     SLNDIFNIKTFDKGRIFVRIEDVHAFREPKNLVEIADYLSSKNIPFTIALIPAYVNPK
                     NHKVITLSESPEIVKAIKYMQDKGGTVILHGYTHQYKKEEVSGEGYEFWDGKKDEPLK
                     ENMKIFVKDRVLNGLRVCIENGIYPLAFEAPHYAMESEGYKELKKYFSTYMGQHQNND
                     KKFSTNTYPYIIRDTEEFNIFIPENLGYIDPEDKFTFQNIKENLNKLSIVRGFSGGFF
                     FHSYLNIEYLKNTIEYLEKQNIEFMNLRDFNNWVKVDEIQIRNNGDEIIVNYDKDLDE
                     ITKSDTRFKSISNISKVLIFIVSISVLIFVIIFIYFKRIDKKKFLK"
     gene            21533..22789
                     /locus_tag="KR294_002093"
     CDS             21533..22789
                     /locus_tag="KR294_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003362983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBH0240171.1"
                     /translation="MRDLNVSEYLFVFSLFSIWSLLLINIILAMGGYIFYFKNFDKEI
                     KEIDEYPMISILVPAHNEAKVIGRTVESLLLLNYPKSKMELIVINDNSSDNSKEILEN
                     IKDRYNNYNFTIINTDSLTGGKGKSNALNIGYTISKGDFIAVYDADNTPDKNALRYLV
                     QTIVMNDELGAVIGKFRTRNKNKNLLTKFINIETLSFQWMSQAGRWQLFNLCTIPGTN
                     FILRRSIIEEIGGWDSKAIAEDTEISFRIYKLGYKIKLVPQSITWEQEPETVKVWIKQ
                     RTRWAKGNIYVLMKYIKNIFKQGRNKIVFDIAYFFSVYFLFLTSVIISDILFVLSISK
                     LVEISIPINFFLIWILSYLLFIIEVSISLTIEKGEATIENIFIVAIMYFTYSQLWLFV
                     AIKGMIEYLKDIIFKREVKWYKTERF"
     gene            22812..24893
                     /locus_tag="KR294_002094"
     CDS             22812..24893
                     /locus_tag="KR294_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis cyclic di-GMP-binding
                     regulatory protein BcsB"
                     /protein_id="HBH0240172.1"
                     /translation="MKKFIISIISLVLFFSNISLIYKVNADETKVKNYKFERDITIDG
                     VIGSNSTFFEVNKNWDIEEVLLHLNFSKSQILNGDVSSLTVLINNVPIKSIKLNAKTN
                     YKNTLEVLVPKDYIIQGYNEIKIKTYKTISDKICQDDSNTGNWMVIHKESYISIRYKQ
                     KKVENSINEYPYPYAEIENNHKLDTTIVVPDNMTRGETTAVFNLASAFGKITKNDDLK
                     LDVKLYSEMKNWSDDNIIYIGKPENTAEEILDILSIKEQTLLSSNCIIKQVDSPYNKN
                     KKMMVVIGSNEDDLIKASNLLIENRLSNQVLSSSVLVNKETNIKINREQKLNLGHLTL
                     KDLGYSDFLLEGAFNQQALFDVKIPTGKVLDDGSKIILNLRYSDNLDFEKSLVTVSIN
                     DVIVGSKKLDRSHSNNDKLELKIPKDIDNKNYYQVKLTFNLSIKNSNCVTRESNNPWA
                     YVSNNSYLALSMKENETLSFENYPYPFVRDDEFNDLTVIMPDYSGSQAMTWMFRLGVT
                     LGANINSHNGNINVIRGKEFSDKYKDTNIVVFGVPHNNSVIKMLNNNLNIKFDKNYSN
                     FISNDKISFIDDYGKNISTIQLIKSPYNNQKNIMVISSMNEKNLYLGMDYLLNKSKVN
                     DLKGDTLIIDEYGEVEDLAYNLKSKKEVKDSSWNMSINKTTKVFLMISFITIIVVMIL
                     SMLYIKKYKRR"
     gene            24930..26015
                     /locus_tag="KR294_002095"
     CDS             24930..26015
                     /locus_tag="KR294_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HBH0240173.1"
                     /translation="MRKYMNKFKLKRSILISLIILIFIFIVYFVSIELKDRSLVNNQY
                     KGKIKSANLSVDYEINQVMKDIDKLGLNTVNVPIIINVESINSDIMSIDNNSKEKAIK
                     LIKKLNKKGISTILEAYPWIENGKLYETDWNPINKKRFFYTWQNAILNELIIDVANPL
                     DVNVLNIGSNFVHLEEYQQNWGEIIDFVQSKFDGFVTYRTNWWYTKKDDLSSKLFYEQ
                     KLNNNFFDKLDFISIAAYFELSNKPVNTVDELISALHSSTVNNRGQNIKQEIYNLYKA
                     HRKPIFFGELGFSNRESASSQPWNHTPSKAVNGEEQARCFEAYKKVFENEDWINGFSV
                     FCVGKIDDEKNFYPSKESIKVIKSWYE"
     gene            26069..27193
                     /gene="wecB"
                     /locus_tag="KR294_002096"
     CDS             26069..27193
                     /gene="wecB"
                     /locus_tag="KR294_002096"
                     /EC_number="5.1.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (non-hydrolyzing)"
                     /protein_id="HBH0240174.1"
                     /translation="MNDIKVMTVFGTRPEAIKVAPLIKELEKRENIKSIVCVTAQHRE
                     MLDQVIETFNINVDYDLDIMEKGQSLNDITCKILNKLPLILNKENPNIILVHGDTTTT
                     LATSLTAFYNKTLVGHIEAGLRTYDKYSPFPEELNRQLTGIIADMHFAPTNLARKNLI
                     SEGKPNNNIFVTGNTAIDALKMTIKENYNHPIIDEIGNDRMILLTSHRRENLGKPMKN
                     IFRAIKRIVDDFEDVQIVYPIHLNPKIRTIADEIFGKFPEKIHIIEPLDVADFHNFLN
                     KSYMIMTDSGGMQEEAPSLGKPVLVLRDKTERTEGIEAKTLKLVGTNEDRIYNSVSDL
                     LINKDNYVQMSKASNPYGDGNASKYIVDIIIKKFNCKYLN"
     gene            27271..28245
                     /locus_tag="KR294_002097"
     CDS             27271..28245
                     /locus_tag="KR294_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HBH0240175.1"
                     /translation="MARKLIKNLGKSKSVKRVKLLFKKIFITVFIVASIVAIFNITKY
                     FEELYKVRDLKSTKIEYYMDVADEAGDGKVQLSWKALLAIDMVIHDEDLSNIKKKDTL
                     DIGEKFIVEDKNDKGEKVYKVKKFNKVLSELKFDSSQKSRARKYMKDLEYTYLGNKQL
                     DSSDEKIKFIKKLEDSAIREYIDYGILPSITIGQAILESGWGNSKLTKQSNNLFGIKA
                     DKAWKGKSVEISTSEHYNEKIVASFRSYNSLQDSVKDHSLFLINNKRYRKHGLFEAKD
                     YISQAQSLENAGYSTAEDKKGNRIYAELLIDVIRSYNLQLIDNKVETK"
BASE COUNT        11307 a         2805 c         4864 g         9412 t
ORIGIN      
        1 atatcaccta aagtaattaa aaggcaatta aagtgaagta gttcaagtat ttctaaaata
       61 agtttaataa attctataat aatttatttt ttgccttaaa attgccttaa aatccaaaca
      121 attttaaaac taatgtacta taaaaagctg gtataattta aatatagtaa aaaataagat
      181 ttatcttatc tattgggatt taattattta atcaatatat ttataccatt taatttaaat
      241 aaaaagtcta ttaaggagtg agcttatgag taagttaatt tatatagcag atgatgaaga
      301 taatataaga aatttggtaa agacattctt aaaaaatgaa ggtcatgatg ttatggattt
      361 taaaacgggt gatgaacttt tagaacaatt taatataaag gagtgtgact tagtaatact
      421 agatataatg atgcctggct caagtggttt tgaagtatgt acaaaacttc gtgagaaaag
      481 tacagtccca ataatcatgc ttactgcaag agatacagat atagattata ttacagggat
      541 aaccttaggt agtgatgatt attttacaaa accatttagc ccaatgtctt tggttatgag
      601 agtaaaatct atatttagaa ggatagagtt tgaaaagaaa caaaattatg ataaatatag
      661 taactcgata gatatggaat taaaatttgg tgatgtaata ataaataaaa agaataaaat
      721 cgttacaagt aaaaatgtaa atatagacct tacaccaaat gaatataacc tattgactta
      781 tttgtttgaa aatatagata gagcaatttc cagagatgaa ttattaaaca aaatatgggg
      841 atacgatata gaagttgaga caagggctgc tgatgataca gtgaagagat tacgtaaaaa
      901 aattttagat acaaatattt taatagaaac tgtatggggg tttggattta ggttgaagga
      961 gaaaagttaa gatgaagaat ggaaatgaca agaatagaat tggaaagatt aaatccaaat
     1021 ttaaattaaa gttctcaaag aaaaatataa gcataaaaac taggattttg ttgagtatac
     1081 tttgtttgat aattatagta tttatgataa tattagtatc ttttaatgta tttcttgata
     1141 catatataaa aacaactgcg aatgaagaat tgacaaagtc tacagaaata gtagaacata
     1201 tggatagtaa ttttagacct attaagccac cacaagatga tggaaagctt cctcccaaag
     1261 tattatctaa ttttatgaga aatgtacaag ataaagttag gatggcagaa acacaatcag
     1321 atgctgatgc tatggtagtt gattctaagt ataacctgat atttccaaca agagaggacg
     1381 atttcttaaa aaatgttgat gagatggagc tgattaggga gtgtattcaa aatgaaaaat
     1441 tagatttaaa ttcagatgca aatacacgga tatctaccag aaataaggat tattatattt
     1501 caactgtaaa aattaccagt atatatggtg aacaagacaa gtatcttata ctttttatag
     1561 acatatcaaa aactctaaat ctagcacaaa agataaatat tgtattaata tctgtaatgt
     1621 gttttgctgg aatattagca atatttacag ctgtgatttt atctgagaaa attgctaaac
     1681 cgataaaaga gttgtgtgag tttgcaaaaa aaatgggtca aggagatttc aaaagaacct
     1741 actttgactt ttcagataaa gaattagtag agctctcaac tgttatgaat aagagtgctg
     1801 agtatctgga taagtatgat aatgaacaaa aaatattttt tcaaaatgca tctcatgaat
     1861 taaggacacc acttatgtct attaaaggtt atgcagaagc tataaaatat aatgttatag
     1921 atagtaaaca tgcaagtgat ataattcttg aagaaagtga taggttaagt gatatggttg
     1981 aagatttatt atacatttct aaaatagata atataactaa agattttgaa cttgtagaat
     2041 gtgatttaag agaagtactt tcaaactgtg gagctaggca aaatgtaaga gctataaata
     2101 aggggataaa gtttatttat gaatttgatg aagaaatggt tttatttgaa tgtgatgaaa
     2161 aaaacatttc caaagcattt atgaatctta tagaaaatgc tttgagatac gctaagagtg
     2221 aaataaaaat agtgtgtaag tataatcaaa aaaatatagt tgtgataata gaagatgatg
     2281 gaattggaat caagaaagaa gatttacctc atgtttttga aagattctat aagggagtag
     2341 gaggaaatca tggaattgga ttatcaatag ttaaatctat tgtaaataag catggtgggc
     2401 gtatatacgt agaaaatggc aaaaaaggag ctaaatttac tatattattt aaattgtaaa
     2461 aaaattagag aaaatataga gatgtttgaa gttgtttttt atatatatct gttgtatact
     2521 gttgaaaaaa gaacaatatt aagctgacat atattacgat agttgacatt taaagtaaat
     2581 gcttaaatat agatacgaaa ggaaaagtaa aatctgaagt gtatttaggt ttaagtaagc
     2641 ttcttatttt ataaaaaata tgtatgaaag aacagctgat ttttaatatt acaaatttag
     2701 taacggttgt atttgaagct tttgtcatcc atatgttttt atcagacttt ttaggccaga
     2761 aagaagggta tataaaagtt gtaagatatg ctaaactggg ttttataata tgtttaggat
     2821 tctgtaattt aataacttta aaccctaaaa tcacaatgcc tttaattttc atccttattt
     2881 tttcaacatc atttttatat aaaggaaatt taaagacacg attgtttact actgttttat
     2941 taagtatatt ctttatactg tcagaaattg tagttacaag tatttttgtt ttatttgtaa
     3001 aagaaggctt tgaaataatg cttgaaaata atagtataag agtattggcg acaattttat
     3061 ctaaaattgt ctttttgttg acttgtaaaa ttatttgtct atttaaaaaa gatgtacatt
     3121 tagatatgcc cataaagtat tggctccctt tatttttaat acctatattt agtttatttc
     3181 tgtctgtttc tatctttgat gtaagtaaat tttttagtct tgaaagttta aaatttctaa
     3241 gcttaatatc tagtgttggt attttatata ttaattttat tgtcttttat ttatttaaat
     3301 ttattataga taaaactaaa ctatctatga aatatgaact acttgaaaaa gaaataattc
     3361 ataaggaaga attaagactt agtaatgagt gttataaaat tattgttgaa cagactgatt
     3421 ctgtcgtttt cgaatggaat atcaaagaaa ataaatcatt tgtatcgcag gcttggactg
     3481 aaaaatttgg atataacaat gcatgtaaga atatttttaa agaaattaaa gataaagact
     3541 tagttcattc tgaagataaa gctatatttg aaggttttct tgaaagtatt aaaaaaaaga
     3601 atatgcacaa tcaagcagta tatcgtttaa aaaaatctaa tggtgaatat atttggtgta
     3661 gaacatcaat tacaagcatt tataatgatg aaaatgaact tttaagagtt gtcggagtaa
     3721 ttgtagatgt agatagtgat ataaaaaaat atgaagagtt aagaactaga gcagaaagtg
     3781 actcattgac caatatatac aataaaggta catttgaaaa attagtggaa gaaactatag
     3841 ttatgaatac aggtgataaa aaagatgcat tattcattat tgatttggat gattttaaag
     3901 aaataaatga taattttggt catccatttg gtgattttgt actaaaaaca tttgctgata
     3961 agatacaaac tagttttggt agtaaagact tagtcggaag aattggtgga gatgaatttg
     4021 ttgtatatat gcaagattat gttacagaag taaatttgca taaaaaagct aaagaattaa
     4081 atagagtact ttcggataat tacactgatt tgagttttag ttttgatgct tctgtcagta
     4141 taggtattgc aaggtatcct caagatggaa cttcattttt tgaattgttt aaaaatgcag
     4201 atagagcact ttatagcata aaagcatcag gtaaaaattc atattgttta tttgaagaag
     4261 aactatatgt acagtgaatt tgaatttaga ttttatgtga gagtaagatt tatatatact
     4321 tgtggctgtc tgatttataa aatatgttac tttgtatatt tttatatgtt tcagtaaggt
     4381 taattaacat aagcaaaggt gtaagtaaat ttatattagt ttaagtttac ttacaccttt
     4441 ataaaaatac aaataataga ttcatttaca ttcttaaatg attaaagctc tttaccttct
     4501 aaacatgcat aacatatcgt tataattcca gtaaataaga ctaaaatacc cattcctaag
     4561 attacagttt cattatctat tactccaaat gtttttaaag taacttattt cgctttgtat
     4621 cataataatt tgtctctttt tacattttaa cttctgctga gatttgagtt agatattcgt
     4681 tagaatctcg cacacttata tcatatagaa gatattcttc ataaacaaaa tccccaatac
     4741 gtaaattatt ctgattaaaa aaatttaata acttttcata agccttgtaa atagtttcat
     4801 aactcccttt atgataagca gttacataaa gtccctttgg tttgattgat acaggatatt
     4861 tcttgtactc tttattaact tttgtaaata aatatgaata tgattcaaag tctttattaa
     4921 ttatatcttc acctttaatg attgagccaa tcgtaccata atcactcaat tcatagttgt
     4981 ccataaagtt aatacattca tataaaaaat tttcttcctc atctcctaaa aactgttctt
     5041 tatatgtaac aggtgttttg accaagtact cttcttcatg ttcttttaaa gtaatagtat
     5101 tcgcatctat attacaggca tttttagtga atgaaatagt agattccatt agagcttgaa
     5161 tattatttag tttttcaatt tcatttttaa tatcaatggt tttcttttct aaaagctcaa
     5221 ttagtaaatt aggtgttctt ttgtctatat aagctttaat ttcttttaaa ggcattttta
     5281 cttccctaag tgaagaaatt ataccaaaaa tgctaagttg atggtatgag tagtatctat
     5341 atccattttc tttctttaat tctggtgaga aaagacctat atcatcataa tggaaaagtg
     5401 tttttttatt gattccacaa atctttgcaa attctccagt tgtaaaataa ttttttgaaa
     5461 cttgactcat aattataatt cctccttgac tatcctgtta cagtatagtt tatcatagta
     5521 ttttgtaaag gagtgtgatt atatgaaaaa attaattcat tttttaaaac catatagagt
     5581 tttaattgtt gtagttttga tatttacgtt tttacaaaca cttggaactt tgtatatacc
     5641 aacacttaca gcaaatatag taaacaatgg tgtagtaaag ggagatatag attatattgt
     5701 aaaaacaggt ttaatgatga tgatagtagc tggtataaca gctttatcag ctgtgttagt
     5761 ttgtaaagta tcagcaaatc tttcatctgg attttgtaga gatattagag aagcagtatt
     5821 tataaaatca caagatttat caataaatga ttttaataat ataggtacag catcaatgat
     5881 tactaggagt actagtgata ttactttaat aggtcagtct gtgtttatgt ttattcaatt
     5941 agtattacca gcaccaatta taactgtttc tggtctattc ttagcatatt ctatagataa
     6001 agcaatgaca attattattg ttgtagtaat gtttttattc atgctttcag catttttagt
     6061 tggtaaaaag cttataaagt tgtttaaaat gatgcaaata aaaatggaca atatgaatag
     6121 ggtgttacgt gaggtagtaa ctggagtaag agttataaga gcttttaata ggagtcattt
     6181 tgaaaaaaag agatttgata gaactgcaat agattattct gaaacagcaa tttcaataaa
     6241 taaaatattt gcagtactta tgcctattgt aatgttaata atgaatttag gtatagtaag
     6301 tattatttgg tttggtggga tgagagtcag taatggaaat atggaaatag gtcatataat
     6361 ggcacttgtt gaatattgta tcttaatttt attctattta atcatgggag taatggtatt
     6421 tatgtacata cctagagcag gtgcatgtgc agatagagta aatcagatat tagatataga
     6481 acctgaaatt gtagatggaa atggtcataa agatactgtc tcagagagag gacatttagt
     6541 atttaaaaat gtaacctttt catatgcaca atcagaagaa cctgtgttaa ataatataac
     6601 atttgaagca aaatctggag aagtaactgc aattatagga agcactggct caggcaaatc
     6661 tactattgca aatataatac cacgtttttt tgaaattcaa tctggagaaa tatctataaa
     6721 tggtcaggat attaagaaga ttcctcaaaa agaacttaga gataagattg gatttgtacc
     6781 acaaaaagct tttttattta gtggaacaat agaagaaaat ataaggtatg gaaaagaaga
     6841 tgcaagtatt gaagaagtaa agcatgctgc aagtatagct caagctgatg aatttatttc
     6901 tgatatggaa gacaagtatg actcatttgt agcacaaggt ggaaataatt tgtcaggtgg
     6961 tcaaaaacag agaatatcca ttgcaagagc gttagttaga aagcctgaag tatatgtctt
     7021 tgatgatagt ttttctgcat tagattttaa aacagataaa agacttagaa aagcgttgaa
     7081 aaatgaaatc aaagattcat cagctataat tatagcacaa cgtataagta caatcatgga
     7141 tgctaatcag attatagttt taaatgatgg aaaaattgta ggtattggaa aacataaaga
     7201 tttacttgaa aattgtgaag tttataagca aattgcggat tcacaactta gtaaagaaga
     7261 acttgcataa aatgaagaat taatctgata tttggaggtg tatgatatga gtgaaaaaag
     7321 aatagatgaa caagatatag aagtacttag ttttgaagat ggcatgtcag cagaaaaagc
     7381 taaggatgca aaaaaaacta ctaagagatt attaaaatat atggcaaaac aaaagtttaa
     7441 aatattaatt atttttattt cagtattgat aagttcagcg cttacagttt tagcacctat
     7501 ggttatggga aaagctattg accaactatt taatggaata aaaactgcag tccaaacagg
     7561 tacaaaattc agtgtgaatt ttagtactat gggggggata gtatcaatac ttctagggtt
     7621 gtacttaatt agtgcagtat ttatatatat tcaacagtat attatgtcag gagttgcaca
     7681 aaatctagtt cttagcatga gaaaagattt aagtgataaa ctcaataaac ttcctcttaa
     7741 gtactatgat tctcataaaa agggggaaac acttagtata gtaacaaatg atttagaaaa
     7801 agtagcagat agtttacaag aaggattaat gcaacttatt acagcagtag ttacagtagt
     7861 tggttctatt gtaatgatga taagtataag tgtaccactt acaatagtat cagctataac
     7921 attacttgtt tcattgggta ttactgttgt aattgcaaga aaatcacaag aaagattctc
     7981 tgaaaatcaa aaggcactag gagagttaaa tagcaatata gaagagatat ttactggtca
     8041 aatagtggtt aaagcattta gtaaagaaaa ggatactata agaaacttta aaatattaaa
     8101 tcaaaatctt tataatgcaa gtagaaaagc acagttttcg tcatatgcaa tatctccaat
     8161 tattagattt ataaacctaa ttggctatgt tattatagca gttgtaggtg ggatatttgc
     8221 atcaactgga gcaatgactc ttggtagtat acaagcgttt attcaatatg taaatcaagc
     8281 atcagagcct actacagaaa tatcttatat tgtaaatatg cttcaagcag caatagcatc
     8341 tgcagagaga gtttttacag ttatggacga ggtggaagag ataaaggatg aagaatcttc
     8401 aaaggttatt agcatgccta aaggtaaagt acaatttgag catgttaaat ttggatatag
     8461 tgatgatttt attcttatga aagatattaa tatcaatcta aatgcaggag ataagattgc
     8521 aattgttgga cctacaggag ctggaaagac aactcttgta aatttactta tgagatttta
     8581 tgagatacaa ggtggaagaa ttactattga tggtgttaat ataaaagatt taaagcgtgg
     8641 agaacttaga actatgtttg gtatggttct tcaagataca tggctgttta atggaagtat
     8701 aaaagaaaat attgcatata gtaagtcaga tgccacaatg gatgaaattg taagagcagc
     8761 aaaatcagca agagtagacc attttataag gactttacca caagggtatg acactatatt
     8821 gactgaggat gcttctaatc tatctcaagg tcaaaagcaa cttctaacaa ttgccagggc
     8881 aatactttca gacccatcag tattgattct tgatgaagca acatctagtg tagatactag
     8941 aacagaggta gaaattcaaa aggcaatgaa taacttgatg aagggaagaa ctagttttgt
     9001 tattgcacat agattatcaa ctattcgaga tgctgattta atattagtaa tgaaagaagg
     9061 aactattatt gaacaaggaa gccataagga acttattgaa aagaaaggat tctatgaaga
     9121 actttataac agtcaattta caagtgaata tgatgaagat gttgtatgat tatcaagttt
     9181 taggcaacta aatgattgat aaatattaag ttaaatatag taacatgtaa ggttatatgg
     9241 aataagagta tttctctatt tcatataacc ttttttattt atcaaaataa gataaaattt
     9301 cctttctaaa ttagattgaa gaatgtattt atcaatataa aagtaaaata atcattatta
     9361 ttagtgaagt aaatattgtt tgccacatat atgccataaa gatgcactta ttttacggag
     9421 atttaacaaa gtagtgtaaa gtatactcta aatataaaat aaatcaaata gagttaaata
     9481 aattgagagg tgatataaat agtgaataaa aaattgaact atagatttga aatgaagcac
     9541 aaaataactg aagcagatgt gttagcttta aaatcaagac tctatcaaat aatgaagaaa
     9601 gatgaaaatg catctaaaga tggaaaatat cttattagga gtttatattt tgatactcct
     9661 gaagataaag cacttttgga taaattaaat ggcgttgcaa taagagaaaa gtttaggata
     9721 agattttata ataatgactg ctcttatata aggctagaga aaaaaatcaa acattacaac
     9781 atgacatcaa agctatcaac taatttaacc aaaaaagaag taataaatat actaaataat
     9841 gatattgaat ttctaaaaga gtcgacaaat tgtttattaa gagaatttta tttgaaatta
     9901 aaatgtgaaa gattagaggc aaaaagcata gttgattaca atagagaagc ttttatttat
     9961 ccagttggaa atgtaagagt tacaatcgat agtgatatta aaacttctgt aaattcggta
    10021 gatttattta ataaagattt gccaactgtt tcggtaattg atgagaatat gactgtattg
    10081 gaggttaaat atgatgaatt tataccagat tttataaagg atttaattca aattaataag
    10141 actacctcta cagcagtttc aaagtatgct tcaagtagat tatatattta agaataaagg
    10201 ctatgattta tataaagata tacataaata aggttaaaaa acaaataagt taaaaataaa
    10261 taaaataaaa aataaataag ttaaaaatag gaaggatgat tttaattatg acatttaatg
    10321 atatttttaa atcaagtttt atagaaaacg tatcaggttt ttcatttgtg gacagtgctt
    10381 tagcactagg ttcagctttt ttagtaggtt tgtttatata tatggtctat aaaaagactt
    10441 atatgggaat tatgtattct cgaccattca atgtgtcgct tgtagcactt acaatgctta
    10501 caacttttgt aatattggca gttacttcaa atgtagtttt atccttaggt atggttggtg
    10561 ctttatctat agtaagattt agaacagcaa ttaaagaccc aatggattta gtatttctat
    10621 tttggtcatt gggttcaggt atagttttag gagcaggttt gattccctta gctgtcatgg
    10681 gttcaataat tatgggattg attctaatat tcttttcaaa taaaacaata tctgaaactc
    10741 catatatatt gatggtaaat tgtaataatg aagattcaga agatatagca actgataaaa
    10801 ttaaaaaagt atttactaaa tatcaaataa aatcaaaaag tgttacacca gaaaaaggaa
    10861 tagaattagt gtttgaagta agaatgaaag atggagaaac aagtcttata aatgacttga
    10921 gtcaagtaga tggagttact aatgcagttc ttgtaagtta taatggtgac tatgtagcat
    10981 agagaggagt aatcttttat gaaagataaa aaatttaccc ttcttatctc gattatgatt
    11041 atatttttat gtgctgtagt tggagtttat agtacatcta gcaacaaaag tgttgattta
    11101 tatagtgatg tatatattga aaaatatttt aacagagaca aggttatgga agttaatata
    11161 gagatagatg aaagtgactt gaaggatatg aatgaaaatg ctataaaaga agaatttaag
    11221 gttgcaaaag taactgtaga tggagataca tatggaaacg taggtataag aactaaagga
    11281 aattcaagtc ttatatctgt agcaaatagt gatagtgata gatacagcta taagattaat
    11341 tttgataagt ataatactag tcaaagtatg gaagggctta ctcaattaaa tcttaataac
    11401 tgttactctg acccatctta tatgagagag tttttaacat atagtatttg cgaggaaatg
    11461 ggattagcga ctccagaatt tgcatatgct aaagtctcta taaatggcga atatcatggt
    11521 ttgtatttgg cagtagaagg attaaaagag tcttatcttg aaaataattt tggtaatgta
    11581 actggagact tatataagtc agatgaagga agctcgttgc aatataaagg agatgaccca
    11641 gaaagttact caaacttaat cgttgaaagt gataaaaaga cagctgattg gtctaaaatc
    11701 acaaaactat taaaatcttt ggatacaggt gaagatattg aaaaatatct tgatgtagat
    11761 tctgtcctta aaaatatagc aataaataca gctttattaa accttgatag ctatcaaggg
    11821 agttttgccc ataactatta tttatatgag caagatggag tattttctat gttaccatgg
    11881 gattttaata tgtcatttgg tggatttagt ggttttggtg gaggtagtca atctatagca
    11941 attgatgaac ctacgacagg taatttagaa gacagacctc tcatatcctc gttattaaaa
    12001 aatgagacat acaaaacaaa ataccataaa tatctggaag agatagtaac aaaataccta
    12061 gattcagact atttagagaa tatgacaaca aaattgcatg acatgatagc atcatatgta
    12121 aaagaagacc caacagcatt ttatacttat gaagaatttg aaaaaaatat aacatcttca
    12181 attgaagatt ctagtgataa taagggattt ggtaataaag ggtttgacaa caataactct
    12241 aataacagtg attctaataa taattctaat agtgaaaata agcgctctgg aaatcaaagt
    12301 gatgaaaaag aagttaatgc tgaattaaca tcaagcgtag tcaaagctaa tacagataat
    12361 gaaactaaaa ataaaactac aaatgatagt gaaagtaaga ataatacaga taaagataaa
    12421 agtggaaatg ataataatca aaagctagaa ggtcctatgg gtaaaggagg taagtcaata
    12481 ccaggggttt tggaagttgc agaagatatg agtaaaacta taaaatctca attaagtgga
    12541 gaaacttctt cgacaaagca aaactctggt gatgaaagtt caagtggaat taaaggtagt
    12601 gaaaagtttg atgaggatat gagtggtatg ccagaaccac ctgagggaat ggatggtaaa
    12661 atgccaccag gaatgggtaa tatggataag ggagatatga atggtaaaaa tggcaatatg
    12721 aatatggata gaaatcaaga taatccaata gaagttggag gttttggtaa tagaggagga
    12781 ggctctgtga gtaaaacaac aacatacttc aaattaattt taggtggagc ttcaatgata
    12841 ataatgtcga ttatgttagt aggtgtatca agggtaaaga gaagaagatt tataaagtca
    12901 aaataagatt aaaattgaat ataaataatt ttaatactgt taagtctaaa tatttactta
    12961 gcagtatttt ttagaaaata atgtgtttga ttaataatat aaggtaataa attgataaaa
    13021 attaaataca gcatattaat aatacataat aaagtaataa aaaactgttt aagtataata
    13081 acttatattt agacagtttt tttcatttat aaataatata aatgaaattg aaaacatttg
    13141 aaggatagaa attggttgga taaatgtata aattacttca ccaaaaaata atgacaaaaa
    13201 ctgtaactaa gttgtaataa aatggtagtt atttagcata aaataatgta tcatagaagt
    13261 atattataaa attaataaaa taagattttt gtaagaaaac tgctggcttt tgatatttag
    13321 agtgagtagt taaattatgt ttaggaggag tagaatttgt tgcaaaaagt attatggaaa
    13381 tttttaaagc tagtagtcgg tttatttata tgttcagttg gtatagtatt gacgataaat
    13441 tgtaaccttg gattatctcc ctgggatgta tttcatcaag gactttcaaa tcatatagga
    13501 ataactatag gaactgcttc tataattgta ggctctatag tagttattgc tgatgtcgtt
    13561 cttggagaaa atgtaggatg gggaactgtt tttaacatgc tactaattgg attttttatg
    13621 gatttacttt tatatagtaa tttaattcca gaggctgata atttatttgt aggaataatt
    13681 atgttgatat taggattggt tcttttgtct gttggaatgg tattttatat gggaagtggt
    13741 ttaggaagtg gacctagaga tggtttgatg gttgcaattc aaaagaaaac aggaaaatca
    13801 cttaaattaa taagaggtac tatagaagtt ggagcattaa tagtaggatt tttattaggt
    13861 ggaaaagttg gtataggaac tataataagt gcatttggat tggggtattt cacacaaatg
    13921 gtatttggct tatttaaatt agattgtagt aagattaaac atagatttat agtagatgat
    13981 ataaaattta tcaaagtgta tatgagtggt gagaaaaaag ctgctgttca aaatatagtt
    14041 aagtaattta agaataaatt caacgaaatg ttaagtattt taaattaaca ttttgtttag
    14101 atagataaat tgaatattaa aagaatatta aaatatgagg attgctagaa cactataaaa
    14161 tatagatttc tagcaatttt ttatttgttc aatatttttt tagtactaga agtcttattc
    14221 tctatttaat gaatgaatta atttataatt agagatacta aactttatag atattaatat
    14281 aaacaccttt aaactgtgta ttttccaaag cctttaaaat gcttgtattt attctaaata
    14341 aaaaaataaa aaaatgtcaa aaaaactctt gtattatatc caaattttat atataattac
    14401 ctatgttgtt tagaaatttt aaactcaatg tttagtaaac aaaatgttta gtaaaataaa
    14461 acagaaacta ggaggtgcaa catggatata ggtgaaaaga taaaaagatt aagaacagaa
    14521 aaacaactga cccaggaaga gttagctaat agatgtgaat tgtcaaaggg atttatttct
    14581 caattagaaa ataacttaac atcaccatcc atagctaccc ttatagatat acttgaaata
    14641 ctaggtacaa atttaaggga attttttaat gaaatagatg atgaaagaat cagttttaca
    14701 aaagaagata tgtttgaaac tgaagatgaa gatttaaaat ataaattaaa gtggttaatt
    14761 ccaaattcac aaaaaaatga aatggagcca ataataataa cattgtatcc aggaggacag
    14821 tataaagaag aaaagccaca tgaaggtgaa gaatttggat atgtattagc aggttcaata
    14881 tatgtccata taggcgaaaa gaaaaataaa gtaaaaaaag gagagagttt ttactttaga
    14941 ccgaaagcaa atcactatat atcaaacgag ggcaaaacta cagcaaaagt gatttgggta
    15001 agtacgccac catcatttta gaatagaggt gtttaataat tggtagaaaa tataatagaa
    15061 ttaagggata tatctaaaca ttatgaagaa cttactgttt tagataattt caatttagat
    15121 ataaagaaaa atgagtttct aacattgctt ggaccaagtg gatgtggaaa aactacaaca
    15181 ttaaaaataa tagcaggatt tgagtatgct gatgatggta aagttttatt tgaaggtaag
    15241 gagataaata atttgccacc atatgaaaga caagtaaaca cagtatttca aaaatatgct
    15301 ttatttccac acatggatgt ttatgaaaat gtagcttttg gattaaaaat taaaaagact
    15361 ccaaaagatg taatagatgc taaagtaaaa gaggttttga aacttgttgc actagaaggt
    15421 tttgaaagac gacaagttga atcattgagt ggaggacaac aacaaagaat tgcaatagca
    15481 agagctctag tcaatgaacc aaaggtatta ttactagatg aaccacttgg agcacttgat
    15541 ttaaagttaa gacaagagat gcaaatagaa ttaaagagaa tccaaaaaaa attaggaata
    15601 acatttgttt ttgtaactca tgaccaagaa gaggctctta ctatgtcaga tactattgtt
    15661 gtaatgtata agggcaaaat tcaacaaatg ggaacaccac aagatatata caatgaacct
    15721 aaaaattcat ttgtagctaa gtttataggt gaaagtaaca tatttgatgg aattatgata
    15781 gaagattata aagttaattt ctgtaataga gattttgagt gtgttgataa aggattcgaa
    15841 aaaaacgaaa atatagaagt agtaataaga ccagaagata taaaaatggt aaagccagaa
    15901 gaaggaatgt taaaggggaa agttacatct acagtgttta aaggagtgca ttacgagata
    15961 gaattgaatg aaaatggaag attgtggata cttcataata ctaaaaatgc tgaggttggg
    16021 actgaactag gcatggatat atatccagaa gatatccata taatgagaaa agagaataac
    16081 taagatgaaa agaaaatctt ttttagcata tccatatgta gtttggagtg cgatatttgt
    16141 aataattcct ttaatattag tagtattttt tagttttaca aaagaatcag gtggaggtta
    16201 tgcctttaca cttgagaatt ataaagaagt aattgaccct atatatatga aagtttttgg
    16261 gcgttctatt cttttagcag gaggagctac attaatatgc cttatagttg gttatccagt
    16321 ggcatatata atttcaaagg ctcgtgtaag tagaagaggt tcattaatat tattgtttat
    16381 tcttcctatg tggatgaact ttcttttaag aacatatgca tgggttgcta tattaggaaa
    16441 aaatggactt ttaaatacat ttttaggttg gtttggaata caaccattag caattttgta
    16501 tactaatttt gctatacttt taggtatggt gtataacttt ttaccattta tggttcttcc
    16561 aatatataca gcactatcaa agatggataa tgatttgata aacgctgctc atgacttggg
    16621 tgcaaataat atgacagttt ttagaaaaat tatatttcct ttgagtttgc caggtgtaat
    16681 gtctggaata actatggtat ttatgccagc agtcactact tttgcaatat caagactgtt
    16741 aggtggaggt aaaataatgc tggttggaga tttgattgaa caacagttta cagttgttgg
    16801 agattggaac tttggttcag ctatatcgat atttatgatg atagtaatat taatatctat
    16861 gtctataatg tcaaaatttg gagatgaatc tgacaaagaa ggcggtgggt tactatttta
    16921 aaattaaaga aaataacttc taatatatat ttagcattag tattcttatt tttgtatgca
    16981 cccatatttg ctttggtact attttctttc aatgattcaa aatcaatggc aagatggaat
    17041 ggatttacat ggaagtggta tggtcaatta cttcaaaatg agagtataat gagtgcttta
    17101 tattatacta ttgtaatagc tatattagcg tctgtaatat ctacaatagt aggaactata
    17161 agtgctatag gaatacataa gatgagaggt aagagtaaga aattaatact aaatgtaaac
    17221 tatcttccta ttttaaatac agagatagtt acagcagtag ctcttatgag tctgtttgta
    17281 tttgtaaaaa tggaatttgg atttacaaca atgctattgg cacatataat gttttgtttg
    17341 ccatacgtta tactttcagt tttgccaaaa atgaagcaat tacctgataa tatagaagat
    17401 gcagctatgg acttgggagc aacacctata tacgctctta gaaaagtaat tttaccacaa
    17461 ataaaaccag gtatagtttc tggattttta attgcattta ctatgtcaat agatgacttt
    17521 ataataagtt tctttaatgc tggaaatggt gtaagcaatc tttctataga aatctatgga
    17581 atggctagaa gaggtataaa acctgaaata aatgcattat caacaataat gtttgcagtg
    17641 gttctaggtt tacttttact agctaataaa aaagaatcta tagtaagggg gattaaataa
    17701 tgattaagtt taaaaaagca atatccctta tagctgtagg tatgatgaca gttactttat
    17761 ttacaggatg taataaagca actgattcta caaaagtttt aaatgtatat aatgttggag
    17821 attatataga tgagtctctt atagataagt ttgaaaaaga aacaggaata gatgttcaat
    17881 attcaactta tgatactaat gaaatgatgt atcaaaaagt aaagagtggt agtacacact
    17941 atgatttagt atttccttca gactatatgg tagagaaaat gaaaaatgaa ggtcttttgg
    18001 aaaaattaga ttttaagaat atacctaata tgaaatattt agataagagt tttttaaatc
    18061 ctgtatacga caaaactaat gaatatagtg ttgcatatat gtggggaact cttggaatat
    18121 tgtacaataa gaaagaagtt aaagacccta tggatagctg gaatatactt tggaatccaa
    18181 agtataaggg aaatataatg atgtttgact ctgttagaga tactataggg ataactctta
    18241 aaaaattagg atatagcatg aatagtgtaa atccaaaaga aataaatgaa gctaaaaatc
    18301 ttttaatgaa acaaaaggat ttagtattgg cttatgtaaa tgatgaaggt aaggatagat
    18361 tgcttggtgg agaagtggca atgggtatgc tgtattctgg agatgcagtt acactaatgg
    18421 agcaaaatcc tgaccttgat tatgctatac ctaaagaggg aactaataaa tgggtagatg
    18481 ctatgtgtgt acctacaaca gcacaaaata agaaagaagc tgagctgttt ataaactttt
    18541 tattagaccc agagaatgca aaagtaaatg ctgagtacat tgggtattca acacctaata
    18601 caggagcact aaaattatta gacccagaaa taactcagaa tcctgttgca tatccatcta
    18661 aagaagtact tgataaatgt gaaacttttg aagatattgg tgaaaatata aaattatatg
    18721 acaaggcttg gatagagtta aaatcaaaat agggtcttgt tgttttaagt aaatttactt
    18781 aataaatact taataaaact gttctttttt agaaaattta ttttctaatt attgaacagt
    18841 tttatttttt gtttaagtta tattcatatg caatttaaat agtttattaa taaatgaaaa
    18901 cttatttgta taatgacttt aataataatt agaaaaaatg ggcaacttaa tagaataatt
    18961 ggaggtgtaa atttataaaa aatgaatagg ataaataaaa aaatagattt attaatattg
    19021 gctttgctcg tttttatatt tttaattgtt ggaatagtaa tactatcgat taggacagaa
    19081 aataaattga atgtgttcat aatgttagca ataatttttt ttataataat gttaacttat
    19141 ttatcaaatt cagtagtggg gttgataaca agttcaataa ttatatttat gtatacatcc
    19201 tatattttat ataacaatat tactcacaat atggatgttg aatttatatc atatatgtgg
    19261 ataatagcaa caccagtatc ttcaattata atgggtaatc tgaacaaaag cataaatgaa
    19321 ttgcaaaata caaataaaaa actatctgaa cagtataagg aattagtgac tattgatagt
    19381 gaaactggac ttagaaattt aaagattttt tataatgatg taaatatgga gataagtaaa
    19441 tctattagac ataatactga tttttctctt atgatagtaa aattaccata ctacggaaac
    19501 ctacagacta tatttggtga aaacaaaact aataaaatag taaaatatat tggttcaaat
    19561 attatagaat gtacaagaaa tgaagatata atttatagtt tacaaaaaga tatgataggg
    19621 atactaatgc caaatacatc tttggaaggt tcaaaagttg ttaaagacag aataaagaaa
    19681 aggataaaag aattaaattt agatttaaac aataggggaa aatatgtaaa tatagatgtc
    19741 aaaattgcat ttttacaata taagagtagt tttggagata gtataaattt taagaatata
    19801 gttgaagagg aacttcaata tgatgtttaa aatatttaat aaaagtctat taaaattagt
    19861 agttgtatta tcaatagtac tgacaatatc aaattttagc ttatcttcat atgcatcaga
    19921 aattacttcc agcacagata aggtattaat catatatgat tctaagaaag aaacagctta
    19981 taatagagat attttaaata ttatgaggac tctattggga agatttagtt cagatataga
    20041 gctattaaaa ttgagtaact atgatggtga gataaataaa aattattaca gtcatatatt
    20101 tattttagga atcaatgaaa actcatataa taatgataaa aacactaaaa acttgattag
    20161 ttccttaaat tcatataaag gaactatatg ttggttagga tatggtatag aaaatctttt
    20221 ggaacataaa aaatacaatt tagactatgt aggaaaaaca aacaatatag ttagtgtaaa
    20281 ttatagaggt aaatcatata acttggatga acattatgtt tttaacattg tagaatcaaa
    20341 agatacaagt aataaagtaa taggaagtat taatgatacc ttaaataagt atccatatat
    20401 aataaatgat aaaaatcttt tttatgtatc aaaattagat ttagatggag ttttatttta
    20461 tatattttgc gattcactta atgatatttt taatattaag acgtttgata aaggacgtat
    20521 atttgtaaga atagaagatg tacatgcttt tagagaacca aaaaatcttg tagagatagc
    20581 ggattattta agtagtaaga atataccatt tacgattgca ttaataccag catatgtaaa
    20641 tcctaaaaat cataaggtaa taactttatc agaaagccct gaaattgtca aagcaataaa
    20701 atatatgcaa gataaaggtg gaactgtgat attgcatgga tatactcatc aatacaagaa
    20761 agaagaagtt tctggagaag ggtatgaatt ttgggatggt aaaaaagatg aacccttaaa
    20821 agaaaatatg aagatatttg tcaaagatag agttttgaat ggtcttagag tatgtataga
    20881 gaatggaatt tatcctcttg catttgaagc gccacattat gcaatggaat cagagggata
    20941 taaagaatta aaaaaatatt tttctactta tatggggcaa catcaaaata atgataaaaa
    21001 atttagcaca aatacatatc cttatattat tagggataca gaggagttta atatatttat
    21061 acccgaaaat ttaggatata tagacccaga agataagttt acttttcaaa atataaaaga
    21121 aaatttaaat aaattatcca ttgtaagagg ttttagtgga gggttcttct ttcattcata
    21181 tttaaacata gagtatctaa aaaacacaat agaatattta gaaaaacaga atatagaatt
    21241 tatgaattta agagatttta ataattgggt aaaagttgat gaaatacaaa taagaaataa
    21301 tggagatgaa attatagtca actatgataa ggacttagat gaaataacta aaagtgatac
    21361 tagatttaaa tccatatcca atattagtaa agttttaata ttcatagtat ctataagtgt
    21421 tttaatattt gtgattatat ttatatattt taagagaata gataaaaaga aatttttaaa
    21481 ataaatgatt ttatattaga atcaatattt taaaatattt taggagaaat ttatgagaga
    21541 tttaaatgta tcagagtatt tgttcgtatt tagtctgttt agtatatggt ctttattgct
    21601 tataaatatt attttagcta tgggtggata tatattttat tttaaaaact ttgataaaga
    21661 aataaaagaa attgatgaat atcctatgat atcaatactt gttcctgctc ataatgaagc
    21721 taaagtgata ggtagaactg tggagtcttt gctattactc aattatccta agagtaagat
    21781 ggaacttatt gttataaatg acaattcttc tgataatagt aaagaaattt tagaaaatat
    21841 aaaggatagg tacaacaatt ataatttcac tataataaat acagatagtt taacaggtgg
    21901 aaaaggaaag tctaatgcat taaatattgg atatacgatt tcaaaaggag attttatagc
    21961 tgtttatgat gcagataaca caccagataa aaatgcactt agatatctag tacaaactat
    22021 agtaatgaat gatgaattag gtgctgttat tgggaaattt aggactcgaa ataaaaataa
    22081 aaacctatta accaaattta taaacataga aacattaagc tttcaatgga tgtcacaagc
    22141 tggtagatgg caacttttta atctatgtac aataccagga actaacttta tattgaggag
    22201 aagtatcata gaagaaattg gaggatggga tagtaaagca attgcagaag atacagaaat
    22261 aagttttagg atatataaat tgggatacaa gataaagctt gtaccacaat ctataacatg
    22321 ggaacaagag ccagaaactg ttaaggtgtg gataaagcaa cgtactagat gggcaaaagg
    22381 gaatatatat gtattaatga aatatataaa aaatatattt aaacagggaa gaaataagat
    22441 tgtgtttgat atagcttact ttttttctgt atattttcta tttttaacat ctgtaattat
    22501 atccgatatt ttatttgttt taagtatatc taaactagta gaaatttcta ttccaattaa
    22561 cttttttcta atatggatac tatcttatct tttatttatt atagaagtga gtataagcct
    22621 tactatagaa aaaggtgaag caacaattga aaatatattc atagtggcaa taatgtattt
    22681 tacatactct caactatggc tgtttgtagc tataaaagga atgatagagt atctaaaaga
    22741 tataattttt aaaagagagg ttaaatggta taaaacagaa agattttgat tcatgtacag
    22801 gaggaattaa catgaaaaaa tttattatat caattatatc tttagtattg tttttttcaa
    22861 atatatcact tatatacaaa gtaaatgctg atgagactaa agttaaaaat tataagtttg
    22921 aaagagatat aactattgat ggtgttatag gaagtaatag tacttttttt gaagtaaata
    22981 aaaattggga tattgaagaa gttttattgc atcttaattt tagtaagagc caaatattaa
    23041 atggagatgt ttcaagttta actgtattga taaataatgt accaataaaa tctattaaat
    23101 taaatgctaa gacaaattat aaaaatacat tagaagtatt agttccaaaa gattatataa
    23161 ttcaaggata taatgaaata aaaataaaaa catacaaaac aatatctgat aaaatttgcc
    23221 aagatgattc caatactggg aactggatgg ttattcacaa agaatcatat atatcaatta
    23281 gatataagca gaaaaaggtg gaaaactcaa taaatgaata tccgtatcca tatgcagaaa
    23341 ttgaaaataa tcataaatta gatacaacta tagtagtacc agataatatg actagaggag
    23401 agactacagc agtgtttaat ttggcatcag catttggaaa aataacaaaa aatgatgatt
    23461 taaagttaga tgttaaatta tattcagaaa tgaaaaattg gtcagatgat aatattatat
    23521 atattggtaa acctgaaaat acagcagaag aaattttgga tattttaagt ataaaggaac
    23581 aaaccctatt atcttcaaac tgtataatca agcaagtaga ttcaccatac aataagaata
    23641 agaagatgat ggtggtaatt ggtagtaatg aagatgattt aataaaggca tcaaatttat
    23701 taatagaaaa tagactttct aaccaagttt tatcatcatc agtacttgta aacaaagaga
    23761 ctaatataaa aattaatagg gaacaaaaat taaatttagg tcatttaaca ttaaaagact
    23821 taggatattc tgactttttg ttggaaggag catttaatca acaagctttg tttgatgtca
    23881 aaataccaac gggtaaggta ttagatgatg gttcaaagat tatcttaaat ttaagatatt
    23941 ctgacaattt agattttgaa aaatctttag ttacagtgtc tataaatgat gttattgtgg
    24001 gaagtaaaaa attggatagg tcacattcta ataatgataa gttagaatta aaaataccta
    24061 aagatataga taataaaaac tattatcaag ttaaattgac atttaatttg agtataaaaa
    24121 attcgaattg tgttactaga gagagtaata atccttgggc atatgtatca aataattctt
    24181 atttggcgtt atctatgaaa gaaaatgaaa ccttatcttt tgaaaattat ccgtatccat
    24241 ttgttagaga tgatgaattt aatgatttaa ctgtgataat gccagattat tcagggtcac
    24301 aagctatgac ttggatgttt agattaggtg ttactttagg tgcgaatata aattcacata
    24361 atggaaatat aaatgtaatt agaggaaaag aatttagtga caagtataag gatactaata
    24421 ttgtagtttt tggagtgcca cataataatt ctgttataaa gatgttaaat aataatttaa
    24481 atataaaatt cgataaaaat tactccaatt ttatatcaaa tgataagata agctttattg
    24541 atgattatgg aaaaaatatt tctaccattc aattaataaa atcaccatat aataatcaaa
    24601 aaaatatcat ggtaattagt tcaatgaatg aaaaaaactt atatttagga atggattatt
    24661 tgttgaataa aagtaaagtt aatgatttaa aaggagatac attgataatt gatgaatacg
    24721 gagaggtaga agatttagct tataatttaa aatctaagaa agaagtaaaa gattcaagtt
    24781 ggaatatgag tataaataag acaactaaag tatttttaat gatttctttt attactataa
    24841 ttgtagtcat gatattatca atgctatata taaaaaaata taaaagaaga taatatgata
    24901 aatttattat tttaaaagag gtatataatt tgaggaaata tatgaataaa tttaaattaa
    24961 aaagaagtat tttaatctca ttaataatct taatttttat atttatagtt tactttgtaa
    25021 gtattgagtt aaaagatagg agtctagtaa ataatcaata taaaggtaag attaaatcgg
    25081 ccaatttatc tgtagattat gaaataaatc aagttatgaa ggatatagat aaattgggat
    25141 tgaatacagt aaatgtacct ataattataa atgtagagtc cattaattct gatattatgt
    25201 caatagataa taatagtaaa gaaaaggcaa ttaagttaat aaaaaaatta aataaaaaag
    25261 gtatttcaac aatattagag gcatatccat ggattgaaaa tggaaaattg tatgagactg
    25321 actggaaccc tataaataaa aaaagatttt tttatacttg gcaaaatgcc atattaaatg
    25381 aacttataat tgatgtagca aatccactgg atgtaaatgt tttaaatatt ggttctaatt
    25441 ttgtacattt ggaagaatat caacaaaatt ggggtgaaat aatagatttt gtacaatcca
    25501 aatttgacgg ttttgtaacg tacagaacta attggtggta tacaaaaaaa gatgatttaa
    25561 gtagtaagtt gttttatgaa caaaagctga acaataattt ttttgataag ttagatttta
    25621 tatctatagc agcatatttt gagttaagta ataaacctgt taatacagtg gatgaattaa
    25681 tttctgcctt acactcatct actgtaaaca atagaggaca aaatataaaa caagaaatat
    25741 ataaccttta taaagctcat agaaaaccta tattttttgg agaattaggt ttttcaaata
    25801 gagaaagtgc aagttctcag ccgtggaatc atactccttc aaaagctgta aatggcgaag
    25861 aacaagcaag gtgttttgag gcatataaga aagtttttga aaatgaagac tggataaatg
    25921 gtttttctgt gttttgtgta ggtaaaatag atgacgaaaa aaatttttac ccatcaaaag
    25981 agagtataaa agttattaag tcttggtatg aataattttg aaagtgtaga atttatatag
    26041 attaaataga tgattaggag agacataaat gaatgacatc aaggttatga ctgtatttgg
    26101 aactagacct gaagctatca aagtagcacc tttaataaag gaacttgaaa aaagagagaa
    26161 tataaaaagt attgtttgcg ttacagctca acatagagaa atgcttgacc aagttataga
    26221 aacctttaat ataaatgtag actatgattt ggatataatg gaaaaaggac aaagcctgaa
    26281 tgatataaca tgtaagattt taaataaact tcccttgatt ttaaacaagg aaaatccaaa
    26341 tataatattg gtacatggag atacaaccac aactctagct acaagtttga ctgcatttta
    26401 taataaaact cttgttggtc atatagaagc tgggcttaga acctatgata aatattctcc
    26461 ttttccagag gagttaaata gacaacttac aggtattatt gctgatatgc actttgctcc
    26521 tactaatttg gctagaaaaa acttgatttc tgaaggaaaa cctaataata atatatttgt
    26581 aactggtaat actgctattg atgctttaaa gatgacaata aaagaaaact ataatcatcc
    26641 tataattgat gagattggta acgataggat gattttacta acctctcaca gaagagaaaa
    26701 tttgggtaaa cctatgaaaa atatatttag agctataaag cgaatagtag atgactttga
    26761 agatgtacag atagtatatc ccatacattt aaatcctaaa atacgaacta tagctgatga
    26821 gatatttgga aaatttcctg aaaaaattca tattatagag cctttagatg tagctgattt
    26881 tcataacttt ttaaataaat cttatatgat aatgactgat agtggaggaa tgcaggaaga
    26941 agctccatca ttaggtaagc cagtccttgt gttgcgtgat aaaacagaaa gaacagaagg
    27001 aattgaagca aagacactta aattagtagg tactaatgaa gatagaatat ataattcagt
    27061 gagcgattta ttaataaata aagataacta tgttcagatg agtaaagcat ctaatccata
    27121 tggagatgga aatgcaagca aatatatagt ggatataata attaaaaaat ttaattgcaa
    27181 atatttaaat tagataagac ctaaaacatt aactaattga tataagattt atgataatat
    27241 taaggaatac aatttttaag ggggagtaat atggctagaa aattaataaa aaatttgggt
    27301 aaaagtaaaa gtgtaaagag agtgaaactt ttatttaaga agatttttat tactgtattc
    27361 atagtagcaa gtatagttgc tatttttaat ataacgaaat attttgagga attatacaaa
    27421 gtaagggatt taaaaagtac taaaattgaa tactatatgg atgtggctga tgaagcagga
    27481 gatggaaagg tccaattaag ttggaaggcc ttacttgcta tagacatggt aatacatgat
    27541 gaagatttaa gtaatataaa aaagaaagac acattggata taggggaaaa gtttatagta
    27601 gaagataaaa atgataaagg cgaaaaggtg tataaggtaa aaaagtttaa taaggtatta
    27661 agcgaattga aatttgactc ttctcaaaaa agtagagcaa gaaaatacat gaaagattta
    27721 gaatacacat accttggaaa taaacaatta gatagtagtg atgaaaaaat taaatttata
    27781 aagaagttag aagactcagc tataagagaa tatattgatt atggaatatt gccctctata
    27841 acaattggac aagctatatt agaatctggt tggggaaatt ctaaacttac aaaacagagt
    27901 aataatttat ttggtataaa agcagataaa gcatggaaag gaaaaagtgt agaaatttca
    27961 acttcagagc attataatga aaaaattgta gctagtttta ggtcgtataa ttcattacaa
    28021 gattctgtca aagaccacag tttattttta attaataata aaagatatag aaaacatgga
    28081 ttgtttgagg caaaagatta tattagtcaa gctcaatcat tagaaaatgc aggatatagt
    28141 acagcagaag ataaaaaagg aaatcgtata tatgcagagc tattaataga tgttattagg
    28201 agttataatt tgcaattgat agataataaa gttgagacaa aataattgtt aactttatat
    28261 gaggagataa caagataaga ttcttttcta caaaaagaat agaaaaattg taaaaaaaac
    28321 taaaaaaatg tattgacttg ttatttaaaa ggtgatatta ttattactgt actcgaaaga
    28381 gaacaaaa
//
LOCUS       DAEPKC010000048        27759 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.048, whole genome shotgun sequence.
ACCESSION   DAEPKC010000048 DAEPKC010000000
VERSION     DAEPKC010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 27759)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27759)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27759
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.048"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            211..1815
                     /gene="rho"
                     /locus_tag="KR294_002098"
     CDS             211..1815
                     /gene="rho"
                     /locus_tag="KR294_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HBH0240176.1"
                     /translation="MRRIFLILDDKVLEGLGSKTLVELREIAKELKIKSITTYKKNEL
                     IEIINSKSKNEEKVNEETKEKNEDIKEDIKNRKENIERESIEKEVEYKSPTKSYNKKE
                     IDTQNISQNQEHRNQRNDYNKTTSVNDSNKSSNISNRMVRNNNKNYYMPKQVDESKIV
                     DEFNTSKEDEVVGVLEILPDGFGFLRGSNYLSTEGDVYVSPSQIRRFNMKTGDKIKGI
                     TRHPKSGEKFRALLYVQKINDENPDTAIQRNAFETLTPIFPEERLTLETNRNEIATRI
                     IDLISPIGKGQRGLIVAPPKAGKTVLLKSVANSIAKNHPNVELIVLLIDERPEEVTDM
                     KESIEGDVIYSTFDQVSSHHVKVAEMVLNRAQRLVEHGKDVVILLDSITRLARAYNLT
                     ISPTGRTLSGGIDPGALHGPKKFFGAARNIRQGGSLTILGTALVETGSRMDDVIFEEF
                     KGTGNMELHLDRKLAEKRIFPAIDIYKSGTRRDDLLLDDEEKTALWRLRREMSNNSVM
                     EITDKVIELIKRTKDNKEFVKSIKNL"
     gene            1968..2168
                     /gene="rpmE"
                     /locus_tag="KR294_002099"
     CDS             1968..2168
                     /gene="rpmE"
                     /locus_tag="KR294_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018591942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L31"
                     /protein_id="HBH0240177.1"
                     /translation="MQKEIQPKYNPVEVRCACGNTFVAGSTKDEIKVEICSECHPFYT
                     GKQKNIEKGGRIDKFKKRFKMD"
     gene            2313..3206
                     /locus_tag="KR294_002100"
     CDS             2313..3206
                     /locus_tag="KR294_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1385 domain-containing protein"
                     /protein_id="HBH0240178.1"
                     /translation="MAKQAVGGQAVIEGVMMQSKDKRAVAVRKSDGEIALKEDRIKSW
                     VRDKNIDKIPFVRGSFVMIDTMIQGIKSLNFSSEFFMEEAEEDKFDLFIKKIFKDKAN
                     DIIIIFSLVIAMLLSAGLFIFIPTLVGGAFSKVMPNDFMLNLIEGIIRIAILFAYIVL
                     ISRSKDIERVFQYHGAEHKSIYCYENDLELTVENARKFKRLHPRCGTNFLFIVMAVSI
                     ILFAFFGWPNPILRIFMRIICVPIVAGLSYEVIRVLGKYDNGFTKIIAYPGMMLQYFT
                     TKEPDDEQLEVALEALKAVVD"
     gene            3224..4072
                     /gene="prmC"
                     /locus_tag="KR294_002101"
     CDS             3224..4072
                     /gene="prmC"
                     /locus_tag="KR294_002101"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HBH0240179.1"
                     /translation="MTIKDIIIKYSDKLKDISDTPRLDTELLLQKTLGVDRLYIHLNL
                     NKELTEEQKTKFMGFAEERLNGRPIAYIVENREFMGLDFFVKEGVLIPRPDTETLVEE
                     IIEICREKKDVSILDIGTGSGAITISLAKYIENSKIMSFDISETALEIAKKNAIINEV
                     GEKIKYINSDLFTAISDSNIKFDIIVSNPPYIKKQDIETLHKQVKDYEPYNALEGGED
                     GLDFYRRITEQGKKYLNKCGILAYEVGHNQAEDVINIMKSNGYKKIYTKKDIQGIDRV
                     VIGYNI"
     gene            4116..5180
                     /gene="prfA"
                     /locus_tag="KR294_002102"
     CDS             4116..5180
                     /gene="prfA"
                     /locus_tag="KR294_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HBH0240180.1"
                     /translation="MLKKLEVLEDTYKDLSEKIGDPDVINDQKVWQKYIKEHADLEPI
                     VMKYREYKSVLDSIKESKEILQEESDEELRELAKMELAEMEEKVAPLEEEIKILLLPK
                     DPNDDKNVIVEIRGGAGGDEAALFAGDLFRMYSRYAERRRWKIELLSASDTGVGGYKE
                     VSFMIKGKGAYSRLKYESGVHRVQRIPSTESGGRIHTSTSTVAVLPEVEDVEVEINPN
                     DLRIDVFRSSGNGGQSVNTTDSAVRVTHIPTGEVVSCQDGKSQLKNKEQALKILKARL
                     YDKALAEQHKDIAAERKSQVGTGDRSERIRTYNFPQGRISDHRINLTLYKLDAFLDGD
                     IDEMIDALITVDQTEKMTAI"
     gene            5309..5989
                     /locus_tag="KR294_002103"
     CDS             5309..5989
                     /locus_tag="KR294_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HBH0240181.1"
                     /translation="MILKVTIIGLLAGVIGTGLGGVISAIFKREVDKYLSFFMGLSGG
                     IMLAVVVFDLMKESMDKMGIINTVIFTFVGALITMYIKTKLDVSGNMASGYLIFISIL
                     LHNLPEGLAIGSSFMSTESLGITLAIVIGLHNIPEGLAMALGLVCNKMKLSKVILFTV
                     IAGLPMGLGSFLGVYFGGVFTSLIGVFLATAGGTMMYVVLEEIFPHSKSVYCIIGFLL
                     GTMIVNYI"
     gene            6018..7058
                     /locus_tag="KR294_002104"
     CDS             6018..7058
                     /locus_tag="KR294_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HBH0240182.1"
                     /translation="MKTIISNIDINNIDYEEIKIQAKLLREGKTVIFPTETVYGLGAN
                     ALDENAVKKIYEAKGRPSDNPLIVHIYEKEEVYDLAKDISDKAKLVIEKLWPGPITII
                     LNKKDIIPYKTSGGLDTVAIRMPSNVIARAIIKEAGIPIAAPSANISGRPSPTKAKHV
                     YEEMNGRVDGIVLGGDSNFGLESTVLDLTEETPMILRPGSITKEVLEELLGEVKLDPS
                     LSKKEDNQKAKAPGMKYKHYSPNADVYIISGKRENVATKINDMIKSNRDKGLKTGVMC
                     ISRNREFYDGEVIDLGNSLEEVASNLFDALIEMDKKGVDVIYSEEFPKTGVGQAIMNR
                     LLKSAGYKVIKA"
     gene            7075..7524
                     /locus_tag="KR294_002105"
     CDS             7075..7524
                     /locus_tag="KR294_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight protein arginine
                     phosphatase"
                     /protein_id="HBH0240183.1"
                     /translation="MNILIVCTGNTCRSPMAEAILRKAIKESGRSIEEYSISSAGIST
                     ANGMGASENSIEVLKEIGIDLSNHRSKVITKKLIDESDIILTMTKSHKEILVQAVPKC
                     KEKVYTFKGFANKNEEDISDPFGGNLDIYRSTMREIMYSVNEIVKKI"
     gene            7541..7993
                     /gene="rpiB"
                     /locus_tag="KR294_002106"
     CDS             7541..7993
                     /gene="rpiB"
                     /locus_tag="KR294_002106"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose 5-phosphate isomerase B"
                     /protein_id="HBH0240184.1"
                     /translation="MKIGLGCDHGGYNLKKEIISYLESKGIECVDYGTNNATDSVDYP
                     VYGEIVANSVINKEVDYGILCCGTGIGISLAANKVPGIRCAVVSDVFSAKMSKAHNDA
                     NMLSLGERVLGKGLALEIVEAWINTDFEGDRHARRVNMIKSIEEKHNK"
     gene            8029..8658
                     /gene="upp"
                     /locus_tag="KR294_002107"
     CDS             8029..8658
                     /gene="upp"
                     /locus_tag="KR294_002107"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HBH0240185.1"
                     /translation="MSKVVETNHPLIQHKLTLMRDKNTGSKDFRELLTEIAMLMGYEI
                     TKDIPLKDVEIETPIQKTSSKVVAGKKLAIIPILRAGLGMVDGLVSLMPAAKVGHVGL
                     YRDPETLKPVEYYCKLPQDIGERDIIVVDPMLATGGSAVAAIDLLKSKGAKSIKLANL
                     VAAPEGIAEVQKYHDDVDIYVASVDERLNEHGYIIPGLGDAGDRLFGTK"
     gene            8959..9774
                     /locus_tag="KR294_002108"
     CDS             8959..9774
                     /locus_tag="KR294_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EF2563 family selenium-dependent molybdenum
                     hydroxylase system protein"
                     /protein_id="HBH0240186.1"
                     /translation="MKNCIVVRGAGDLATAVIHKLHNSGFKVVALEIEEPLAIRRQIS
                     FCEAVYEKKVTVEGVECIFCNTEKEIEEVLSQHKVALIIDPKGEKLSKLNPIVLVDGI
                     LAKKNLGTTKDMAPLTIALGPGFCAGEDVDVVIETMRGHNLGRIITNGRAEKNTGVPG
                     AIKGFSKERVMHSQYDGIMENVCKIGDIVEKGDLLCYINNYEKKHEVRATISGVLRGL
                     LKDGAKVNKNLKILDIDPRKEEVKNAFTISDKARCIAGGVLEAILNNGIYPQN"
     gene            10000..10437
                     /locus_tag="KR294_002109"
     CDS             10000..10437
                     /locus_tag="KR294_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dCMP deaminase"
                     /protein_id="HBH0240187.1"
                     /translation="MRPSWDEYFMEIAEVVKKRSTCIRRQVGAVIVRDKQILTTGYNG
                     SPRNLEHCENIGCKRQELNIPSGERHELCRALHAEQNAIIQAAHNGISVDGATLYVTT
                     RPCVLCAKMCINAGILKIVYEGDYPDDMSTELLKEAGIELIKF"
     gene            10622..10849
                     /locus_tag="KR294_002110"
     CDS             10622..10849
                     /locus_tag="KR294_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AtpZ/AtpI family protein"
                     /protein_id="HBH0240188.1"
                     /translation="MSKRNTHTEIAKLFSLISQIGLMIVISILGCTFLGKFLDSKLNT
                     TPVLTIIFLLLGVGGAFSGVYKTLIVYTRRK"
     gene            10854..11240
                     /locus_tag="KR294_002111"
     CDS             10854..11240
                     /locus_tag="KR294_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase subunit I"
                     /protein_id="HBH0240189.1"
                     /translation="MDIKLLNQVRSVTKGIVIFDVVLIVLMLITSTLSKPVLLGLIFG
                     SIIAMLNFRLLAISLEKSVTFPAGKAQAYASAQYAVRLFIMAVVLIASATVPHLNIIG
                     TALGLLSTKFVILSKNFINKLKRKEA"
     gene            11243..11947
                     /gene="atpB"
                     /locus_tag="KR294_002112"
     CDS             11243..11947
                     /gene="atpB"
                     /locus_tag="KR294_002112"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HBH0240190.1"
                     /translation="MNQAHYYLIGNFKISETILVSWGIMAFLAIASYFLTRNLKKVPT
                     SKVQIFLEFAVGGLAKMVTDVMGKNTVKRMPYMIPYIGSLFLFFACSNLSPLLGLRSP
                     TTDLDTTAAWAMITFFMIYFAGVKFKGLSYFKELAQPLAIMLPINIIGELARPISLSF
                     RPFGNILGGTIIMGLFYQLLGFISSLIPGLSIPIGEILIPVPLHLYFDLFAGLLQAYI
                     FIMLTMVFISSAGELD"
     gene            12016..12276
                     /gene="atpE"
                     /locus_tag="KR294_002113"
     CDS             12016..12276
                     /gene="atpE"
                     /locus_tag="KR294_002113"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HBH0240191.1"
                     /translation="METAIVAAASAIGAGIAVATGIGAGIGQGIAAAKAAEAVGNQPE
                     AKGDITSTLLLGVAIAESSAIYGLVISIILLFVNPFFKYLGM"
     gene            12399..12896
                     /gene="atpF"
                     /locus_tag="KR294_002114"
     CDS             12399..12896
                     /gene="atpF"
                     /locus_tag="KR294_002114"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HBH0240192.1"
                     /translation="MEKALVGITWEFVFQIVNTFIIFLLLRKLLFKPVLNIIESREND
                     IKSDLVEGEKAKNEGLALKKEYESKINFAKDEGQEIIKQATIRAEQKSDDIVNTAKKD
                     ALDIKEKANKDIEQERQKVINEIKNDISNIALLAASKVIEKDLDKSKHEELIENFIKE
                     VGEAK"
     gene            12893..13438
                     /locus_tag="KR294_002115"
     CDS             12893..13438
                     /locus_tag="KR294_002115"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HBH0240193.1"
                     /translation="MINVIANRYAEALFQLGEEENSTDVLFKELEKVVDMMTKVSKDF
                     YKVLKSPLVSKSEKKNLVEIIFSKEVSSNIKNFLKVLVDKDRISYLEDIELAYKELLN
                     KKNNVIDGVAISAIPMSETDIKELEVKLSNKYNKNVTIENVVDKTILGGVLVRIGNEQ
                     IDGTVKTRLDKMKEKLSEVIS"
     gene            13455..14957
                     /locus_tag="KR294_002116"
     CDS             13455..14957
                     /locus_tag="KR294_002116"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003405060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HBH0240194.1"
                     /translation="MNLKPEEISSIIKQQIKNYENKVELTDTGSVLTVGDGIASVYGL
                     EKAMSGELLEFPGEIYGMALNLEEEVVGAVILGDDSEIKEGDIVKRTGRIVEVPVGEA
                     LIGRVVNSLGQPIDGKGPIAYTKTRPVESEAPGIIDRRSVYEPLQTGIKSIDSMIPIG
                     RGQRELIIGDRQTGKTSIVIDTILNQKGKDVICIYVAIGQKRSTIAQLVSSLEKGGAL
                     DYTIVVSATASESAPLQYIAPYAGAAMGEEFMYNGKHVLIVYDDLSKQAVAYREMSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDELGGGSMTALPIIETQAGDVSAYIPTNV
                     ISITDGQIYLQPELFYSGVRPAVDPGISVSRVGGSAQIKAMKKVAGTLKLAYSQYREL
                     AAFSQFGSDLDEDTKKRLAQGERIVEILKQGEHQPIKVENQVMIIYAVINNHLEDIPI
                     DNIARFESELYAFVDNNYPEISRKILGGEDFTHDLTDAINEFKEKFVVEV"
     gene            14985..15863
                     /gene="atpG"
                     /locus_tag="KR294_002117"
     CDS             14985..15863
                     /gene="atpG"
                     /locus_tag="KR294_002117"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F1 subunit gamma"
                     /protein_id="HBH0240195.1"
                     /translation="MAGAGIKAIKTRMGTVESTKQITKAMELVASSKLRKAKEKAEDS
                     REYFNTLYNTVKDIAQTTRGIRNEFLKEREVKNKCYVVVAGDRGLAGGYNSNVLKESV
                     SHMKGKKETVITVGKKAHEFFSKRNYNIAKDINSVEACGYEDATEISQTIIDLYKKGE
                     VDEVYIAYTKFKSALSQEVEILKLLPLVFEKDTDEQGMAVKEEKQNRSKVQYIPSAEA
                     VLSYIVPQFISGTVYGGILESFASEQGARRTAMESATDNANEMLSNLELSYNRARQSA
                     VTQEITEIVGGVEALK"
     gene            15876..17270
                     /gene="atpD"
                     /locus_tag="KR294_002118"
     CDS             15876..17270
                     /gene="atpD"
                     /locus_tag="KR294_002118"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HBH0240196.1"
                     /translation="MANVGKVVQIVGAVLDVKFDSEQSLPNLLNALVIKLGDKEIVAE
                     VAQHIGDDTVRCIAMSATDGLVRGMEVVDTGGPISVPVGDETLGRIFNVLGKPVDGKP
                     APKSAPKLPIHRPAPAYDELETTAEILETGIKVVDLLAPYLKGGKIGLFGGAGVGKTV
                     LIQELINNIAKQHGGISVFSGVGERTREGNDLYGEMSESGVINKTALVFGQMNEPPGA
                     RMRVALTGLTMAEHFRDEQGQDVLLFVDNIFRFTQAGSEVSALLGRMPSAVGYQPTLA
                     TEMGALQERITSTKKGSITSVQAVYVPADDLTDPAPATTFSHLDAKTVLSRQISSLGI
                     YPAVDPLESTSRILDPSIVGKEHYEVARGVQSILQRYKELQDIIAILGMDELSDEDKL
                     IVARARKIQRFLSQSFTVAEQFTGNPGQYVPVKETVRGFKEILEGKHDDLPESAFLFV
                     GTIEDAVRKAKGSM"
     gene            17273..17533
                     /gene="atpC"
                     /locus_tag="KR294_002119"
     CDS             17273..17533
                     /gene="atpC"
                     /locus_tag="KR294_002119"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F1 subunit epsilon"
                     /protein_id="HBH0240197.1"
                     /translation="MASEFSLKVVTPSNTFYDGDVEMIVVRTTKGDKGVLKGHIPFVS
                     GIPVGTLKIKKEGSFKEAKIAEGFINVTQDKTVILTESAEWI"
     gene            17995..18375
                     /locus_tag="KR294_002120"
     CDS             17995..18375
                     /locus_tag="KR294_002120"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HBH0240198.1"
                     /translation="MNIFDIGVDIIEIDRIRKAVDKNNRFLEKIFTDREIEYFNSKNF
                     KAESIAGNFAAKEAISKSIGTGIRVFNFKDIEVLRDEMGKPIVKTYNNLAKMCIDYNV
                     LEIKVSISHSKDYAIANAITIIKD"
     gene            18390..18851
                     /locus_tag="KR294_002121"
     CDS             18390..18851
                     /locus_tag="KR294_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBH0240199.1"
                     /translation="MMDKTAKEIMTTDVIVAKQDDSIADVANMLIAEKIGGLPVVDSE
                     NRVVGIISETDILKKEKYIEAPLYINLLQGLIFLDDLKKVEKDIKQVAAYKVGELMSK
                     DIIKVHEDDKFDDVANVMIKKSINRVPVVDDDNKLKGIICRYDIIKALYNE"
     gene            18872..19462
                     /locus_tag="KR294_002122"
     CDS             18872..19462
                     /locus_tag="KR294_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240200.1"
                     /translation="MRKKWTIVCIMFLALVIIVIGCQKRQSTKEEVYKDFQKQISDMN
                     YYSCKAEVEVVGNKSPHNYVLIHTYKKTDNYKLEVISPKHLKGKSIEYQGDKILVKNP
                     KISDVVELPNTGKNNQYLFVGDFIKNYLQNEEMKVKLSKGHLVLETFIPGDNKYFNKQ
                     VLYVNADTKNPEKMEVLDKEGVPRFTVKYKDFEYRN"
     gene            19477..20634
                     /gene="alr"
                     /locus_tag="KR294_002123"
     CDS             19477..20634
                     /gene="alr"
                     /locus_tag="KR294_002123"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HBH0240201.1"
                     /translation="MQKITVPTWAEINLDNLRFNLNNIKNLLEEDIKICGVIKADAYG
                     HGAVEVAKLLEKEKVDYLAVARTAEGIELRQNGITLPILNLGYTPDEAFEDSIKNKIT
                     MTVYSLETAQKINEIAKSLGEKACVHVKIDSGMTRIGFQPNEESVQEIIELNKLEYID
                     LEGMFTHFATADEVSKEYTYKQANNYKFMSDKLDEAGVKIAIKHVSNSAAIMDCPDLR
                     LNMVRAGIILYGHYPSDDVFKDRLELRPAMKLKSKIGHIKQVEPGVGISYGLKYTTTG
                     KETIATVPIGYADGFTRIQKNPKVLIKGEVFDVVGRICMDQIMVRIDKDIDIKVGDEV
                     ILFGEGEVTAERIAKDLGTINYEVLCMISRRVDRVYMENNELVQINSYLLK"
     gene            20667..20954
                     /locus_tag="KR294_002124"
     CDS             20667..20954
                     /locus_tag="KR294_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribbon-helix-helix protein, CopG family"
                     /protein_id="HBH0240202.1"
                     /translation="MYDKSKEKIEVTLPDSLISEVDSIVQMENSNREDFAKAAFQFYI
                     TQKKKIHIKESMKTGYREMGQINLSLAELGMTVEEVSSDDKNEGKIAQGEY"
     gene            20923..21306
                     /locus_tag="KR294_002125"
     CDS             20923..21306
                     /locus_tag="KR294_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBH0240203.1"
                     /translation="MKGRLPKVSTNCEIKRGDLYYADLSPVVGSEQGGVRPVLIIQND
                     VGNKYSPTVIVSAITSQINKAKLPTHVEISSNEYGLNKDSVILLEQIRTIDKKRLREK
                     IGCLDENMMIKVDDGLQISLGLFTF"
     gene            21477..22304
                     /locus_tag="KR294_002126"
     CDS             21477..22304
                     /locus_tag="KR294_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HBH0240204.1"
                     /translation="MRDHKGLNEIARIIRRDIVSMIHRAKSGHPGGSLSVVEILTALY
                     FDEMNVDSSNPKMEDRDRFVLSKGHAAPALYATLAEKGYFDKEELNGLRKIGRMLQGH
                     PDMKGTPGVEISTGSLGQGFSVACGMAMASKLDNAPWNVYTLLGDGEVQEGIVWEAAM
                     SAAHYKLDNLIAFLDNNGLQIDGDIESVMSLGSIVDKFKAFGWNVIEIDGHDFDQIFA
                     ALDIAKSTVKKPTMIVAKTIKGKGISFMENQAGWHGTAPSDEELEKALLELGGADNE"
     gene            22297..23238
                     /locus_tag="KR294_002127"
     CDS             22297..23238
                     /locus_tag="KR294_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HBH0240205.1"
                     /translation="MSKMATREAYGKALVKLGQINDNVVVLDADLSKSTKTHDFYKSF
                     PDRFFNMGIAEQNLIGAACGLSTAGKIPFASTFAMFATGRAFEIIRNSVCYPKLNVKI
                     CATHAGLTVGEDGASHESVEDIAIMRAIPNMTVLVPADGVETEKIIFEIAKYNGPVYV
                     RLGRSSVPVLFDEDYKFEIGKGTVLREGKDVSIIACGIMVNEALLAQEKLQEEGISAR
                     VINMSSIKPIDKDLILESAKETNAIVTVEEHSIIGGLGSAVSEVVGESCPTIVKKVGI
                     KDTFGESGTPNELLKKYELTCDDIIKTVKEAIIAKRM"
     gene            23661..24755
                     /locus_tag="KR294_002128"
     CDS             23661..24755
                     /locus_tag="KR294_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240206.1"
                     /translation="MSEKVNVKTVISFAGAYVATVIGSGFATGQEIMQFFSFYGFAGI
                     IGGIISMVLFSWMGASVMSKGKELQLKEPIKIYRVYCGKYLGIFFEWFGPLFLFGVFV
                     VMISGAGATLTEYYGLNPFVGRVGMAVVALLTVSLGLDKLSKILGGIGPIIIIFTLLV
                     GGISLAKNIGNIGEAAQVLSTVKIAKPVPNAYLSGVIYTTYNTIVVMAFLTGLGASAA
                     NKKEAICGGILGGVALMAAAIMMHLAILSDIGNLYSKAIPSLFLADKISPVIGVLFSI
                     ILILGIYTTAVPLLWSVTNRFVDDKHPKFKLITLIAAILGLIGGFLPFDKLVGILYPY
                     TGYMGVIILVCVLYRQITKTSGYQEGISDK"
     gene            24981..25397
                     /locus_tag="KR294_002129"
     CDS             24981..25397
                     /locus_tag="KR294_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240207.1"
                     /translation="MNVKFNIKGIIYGVIALVFVIGGFIFIPSMFVEKSKPIDYTVLQ
                     RNSIPEKILDVMDKYTNEERALAAKIDNKIYIIVTRGNNKYGIEMDKIESVVEEGKDV
                     LRVKIKYKDKEDSFPYIVVETNMSELPDRIELNATK"
     gene            complement(25579..26148)
                     /locus_tag="KR294_002130"
     CDS             complement(25579..26148)
                     /locus_tag="KR294_002130"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HBH0240208.1"
                     /translation="MKKEFRKKVIESRKNKNANFVLSNSNLITEKLLQMEDIRNATNI
                     MLYLNFNNEVQTDNLIKKLLSLKKIVSSPITIKENHTLIPTQITDLKEGLRIGAYGIR
                     EPNEKSPTIDIKALDVVIVPAVAYDIHCYRLGYGGGFYDRFLENLRKDAITIGIAFDF
                     QIFDSIPKETHDAQLDYIVTETRIITPNS"
     gene            26302..27459
                     /locus_tag="KR294_002131"
     CDS             26302..27459
                     /locus_tag="KR294_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S41 family peptidase"
                     /protein_id="HBH0240209.1"
                     /translation="MYLVISKKKAIFLGVILVIITAMVTSAFQLTLGNKVVISKELYE
                     DYKKYDKLLGLESIIKQDFYKKVSDTDLVNGAAKGLFLGTNDKYSGYYTKDEMENLIN
                     DSEGSYVGVGMYIGASKDGGLVVVPMKDSPAEKAGVKSGDKLVKVNGKSVSYKNSDEA
                     VRMMKGKKGKTVELTILREDKQLNFKVKTDQIIEKSIESKVIDNDLGYIEITQFISST
                     YTDFDKALKELKAKNIKGLVIDLRNNPGGMLDICKEVADELIGEGTIVYTKDNKGNTE
                     YLKSDKEKLGLPIVVLTNGESASAAEILTAAIVDNKEGISVGTTTFGKGLVQSVVRLK
                     DGTGYKLTTAQYFTPNGDYINEKGIKPTIEEKDENKQLDVATKWLREQIDK"
BASE COUNT        10938 a         3029 c         5327 g         8465 t
ORIGIN      
        1 ttataagata taaatatagt gataaattta taaaaacgtg ctaagattgg acttgaaata
       61 cagtaatata gtaggtaata atgttttaaa ttttatttat tgaccataat atataaataa
      121 tgatattatt agacttaact gtttaaataa aacttttctt tttcatgcct tcaatttcca
      181 aaataagtat gtatataaat gaatatatag atgaggagga tttttttgat tttagatgat
      241 aaagtattag aaggattagg tagtaagacc ttagttgagc tacgagagat agctaaagaa
      301 ttaaaaataa aatcaattac tacatataag aaaaatgagt taattgagat tataaattcc
      361 aaaagtaaaa atgaggaaaa agtaaacgaa gagactaaag aaaaaaatga agatattaaa
      421 gaagacataa agaatagaaa agaaaatata gagcgtgaaa gtatagaaaa agaagttgaa
      481 tataagagcc ctaccaaatc atacaacaag aaagaaatag atacccaaaa tatttcccaa
      541 aaccaagaac atagaaatca aagaaatgac tataataaga caacgagtgt aaatgatagt
      601 aataagtcat caaatatatc taatagaatg gtcagaaata ataataaaaa ctattatatg
      661 cctaaacaag ttgatgaatc taagatagta gatgaattta acacatcaaa agaggatgaa
      721 gtagtaggtg tacttgaaat tctgccagat ggatttggtt ttttaagagg ttcaaattat
      781 ttgtctactg aaggagatgt ttacgtttca ccatctcaaa taagaagatt taatatgaaa
      841 acaggagaca agattaaggg aataactaga catccaaaaa gtggagagaa atttagagca
      901 cttttatatg ttcaaaaaat aaatgatgaa aaccctgaca cagctataca aagaaatgcg
      961 tttgagacat taacaccaat atttccagaa gaacgactta cactggaaac taatagaaat
     1021 gaaatagcta caagaattat agatttaatt tcacctatag gaaaaggaca aagaggattg
     1081 atagtagcac ctccaaaagc tgggaaaaca gttcttttaa aaagcgttgc aaatagcata
     1141 gctaaaaatc atccaaatgt tgaacttata gtactcctta tagatgaaag accagaggaa
     1201 gttactgata tgaaagaatc tattgaagga gacgttatat attctacttt tgaccaagta
     1261 tcaagtcatc atgtcaaggt tgcagagatg gtgttaaata gagctcaaag attagttgaa
     1321 catggtaaag atgtagtaat tttactagat agtataacta gattggcaag ggcatataat
     1381 cttacaatat ctcctacagg tagaacttta tctggaggta ttgaccctgg tgcacttcat
     1441 ggacctaaaa agttctttgg tgcagcaagg aatattagac agggtggttc tttgacaata
     1501 ttaggaacag cattggttga aactggttct aggatggatg atgtaatatt tgaggaattt
     1561 aaaggtacag gaaatatgga gctacattta gatagaaaat tagcagaaaa aagaatattc
     1621 cctgcaatag atatttacaa gtctggtaca agaagagatg atttattgct tgatgatgaa
     1681 gaaaagactg ctctttggag attaagaaga gaaatgagta ataattcagt aatggaaatt
     1741 acagataaag tcattgaact tataaagaga actaaggaca ataaagagtt tgtaaaatca
     1801 ataaagaatt tgtaaaatca ataatacaaa tgcaaatatg gattatataa actaatagaa
     1861 aaatcacttg aatggcataa taagttgtgc tataataatg tagttgataa tgtaaaaaga
     1921 aagttaatat aattaatttt tttaaataaa gagaagaggt gactataatg caaaaggaaa
     1981 tacaaccaaa atacaatcca gttgaagtgc gttgtgcttg tgggaacaca tttgttgctg
     2041 gttcaactaa ggacgaaata aaagttgaaa tatgttcaga gtgccatcca ttctatacag
     2101 gaaaacaaaa gaacatagaa aaaggtggaa gaatcgacaa attcaagaaa agattcaaaa
     2161 tggactaatt tttataaaag tggagttgga ggaagccaac tcctatttta ttacaaaaaa
     2221 acattcatat tctactttaa attgtctttt tgtattataa taataaatat gtaaaattga
     2281 gtattctaaa tacaataaaa tgaggtgagt ggatggcaaa acaagctgta ggtgggcaag
     2341 ctgttattga aggtgtaatg atgcagtcaa aagacaaaag agcggtagct gttagaaaaa
     2401 gtgacggaga aatagcacta aaagaagata gaataaaaag ttgggtaaga gataagaata
     2461 tagataagat accttttgtt agaggttctt ttgttatgat agatacaatg attcaaggca
     2521 taaaaagctt aaacttttct tcagagtttt ttatggaaga agctgaagag gataaatttg
     2581 atttatttat aaagaaaatt tttaaagata aggcaaatga tataattata atattttcat
     2641 tggtcatagc aatgttactt tctgctggat tattcatttt tatacctaca ttggtaggag
     2701 gagctttttc taaagtaatg cctaatgatt ttatgcttaa tttaatagaa ggaatcataa
     2761 ggatagctat attatttgca tatatagtat tgatttcacg aagtaaggat atagaaagag
     2821 tctttcaata tcatggagca gaacataaat ctatatattg ctatgaaaat gatttagaac
     2881 ttacagtaga gaatgctaga aaatttaaaa gattacatcc tagatgtggt acaaatttcc
     2941 tatttatagt tatggctgta tcaataatat tgtttgcatt ttttggttgg ccaaatccaa
     3001 ttcttagaat atttatgaga attatatgtg tgcctatagt agcaggttta tcttatgagg
     3061 taattagagt tcttgggaaa tatgataatg gatttactaa aattattgca tatccaggaa
     3121 tgatgttgca atattttaca acaaaagagc ctgatgatga gcaattagaa gttgctttgg
     3181 aagcattgaa agcagtagta gattagagaa aaggatattt gttatgacga taaaagatat
     3241 aattattaaa tattcagata aactaaaaga tataagtgat actccaagat tagatacaga
     3301 gttattgtta caaaaaacat tgggtgttga tagattatat attcacttaa atctgaataa
     3361 agagctaact gaagaacaaa aaacaaaatt tatgggtttt gcagaagaaa gattaaatgg
     3421 aagaccaata gcatatatag ttgaaaatag ggagtttatg ggattagatt tttttgttaa
     3481 ggaaggcgta ttgattccaa gaccagatac agaaacttta gtagaagaaa taattgaaat
     3541 atgtagagaa aaaaaagatg taagtatatt agatatagga actggttctg gagctattac
     3601 aataagttta gcaaagtaca ttgaaaattc taaaatcatg tcttttgata tatcagagac
     3661 agcattagaa atagctaaaa aaaatgctat tataaatgaa gttggtgaaa aaataaagta
     3721 tattaattct gatttattta cagcaataag tgatagtaac ataaaattcg atatcatagt
     3781 ttcaaatcca ccatatatta aaaaacaaga tatagaaact ctgcacaaac aagttaaaga
     3841 ttatgaacca tataatgctc ttgaaggtgg agaagatgga ttagactttt atagaagaat
     3901 aacagaacaa ggtaagaaat atttaaataa gtgtggaata ttagcatatg aagttggtca
     3961 taatcaagct gaagatgtaa taaatattat gaaaagtaat ggatataaaa aaatatacac
     4021 aaagaaggat attcaaggca ttgatagagt tgttataggt tacaatatat gatataatca
     4081 acaattgata tgttacattt aatcgaggtg aaagtatgtt aaaaaaatta gaggtattgg
     4141 aagatacata taaagactta agtgaaaaaa taggtgatcc ggatgtaata aatgatcaaa
     4201 aagtttggca gaaatatata aaagaacatg ctgacttgga acctattgtt atgaaataca
     4261 gagagtataa aagcgtttta gatagtataa aagaatcaaa agaaatttta caagaagagt
     4321 cagatgaaga attaagagaa ttagctaaaa tggagttagc tgagatggaa gaaaaagtag
     4381 cacctctgga ggaagaaata aaaatactat tattgcctaa agaccctaat gatgataaga
     4441 acgttatagt tgaaattaga ggtggagctg gaggagatga agcagctcta tttgctggtg
     4501 atttatttag aatgtactca aggtatgctg aaagaagaag atggaaaata gaattattga
     4561 gtgcaagtga tactggagtt ggtggatata aagaagtatc ttttatgata aaaggtaaag
     4621 gtgcttattc aagattaaag tatgaatctg gagttcatag agttcaaaga ataccatcaa
     4681 ctgaatctgg tggaagaata cacacatcaa cttctactgt tgcagtatta ccagaagttg
     4741 aagatgtaga ggttgaaata aatccaaatg atttaagaat agatgttttc cgttcttcag
     4801 gtaatggagg acaaagtgtc aatactactg actctgctgt tagggtaaca catataccta
     4861 caggtgaagt agtatcttgt caagatggaa aatcacaatt aaaaaataaa gagcaagctt
     4921 taaaaatatt aaaagctaga ctttacgata aagcattggc agaacaacac aaagatatag
     4981 cagcagaaag aaaaagccaa gtcggaacag gagacaggtc agaaagaata agaacatata
     5041 atttccctca aggtagaata agtgaccata gaataaattt aactttatat aagttagatg
     5101 cattcttaga tggagatata gatgaaatga tagatgcttt aattactgtt gaccaaacag
     5161 aaaaaatgac tgcaatataa gtaatgtttt aaagaagctg tttcttccta gaaattattt
     5221 tctattttga aacagctatt ttgcatttta ggtcatgtta tcatattcta ttgtatataa
     5281 ttgttatata caagtatagg agggttatat gatactaaaa gtaacaataa ttgggctttt
     5341 ggcaggtgtt atagggacag gattaggagg agtaatatca gccattttta aaagagaggt
     5401 cgataaatat ctaagttttt ttatgggatt atctggtgga ataatgttgg ctgtagtggt
     5461 gtttgattta atgaaagaat ccatggacaa aatggggata atcaatacag ttatatttac
     5521 gtttgttgga gctctcataa ctatgtacat aaaaacaaaa ttagatgtgt ctggaaatat
     5581 ggcatctgga tatcttatat tcataagtat attactacat aatttaccag aaggactagc
     5641 cattggttct tcttttatgt caactgaaag tttaggtatt acacttgcta tagttatagg
     5701 tctacataat ataccagaag ggttagctat ggcattaggc ttagtttgca ataaaatgaa
     5761 actaagtaaa gttattttgt ttactgtaat agctggatta cctatgggtc taggaagttt
     5821 tttaggtgtt tattttggag gagtatttac ttctcttata ggagtatttc ttgctacagc
     5881 aggaggtact atgatgtatg ttgtattgga agaaattttt ccacattcaa aaagtgtgta
     5941 ttgtataatt ggtttcttgt taggtacaat gattgtaaat tatatataaa attaaaatga
     6001 aagcaggcat acaaaagatg aaaactatta taagtaatat tgatataaat aatattgatt
     6061 atgaggaaat aaaaatacaa gcaaaacttc ttagagaagg taaaacagtt atttttccaa
     6121 ctgagacagt atatgggttg ggtgcaaatg cattagatga aaatgcagta aagaagattt
     6181 atgaagctaa aggaagacct agtgacaatc cattgatagt ccatatatat gaaaaagaag
     6241 aagtatatga cttagccaaa gatataagtg ataaagctaa acttgttata gaaaagcttt
     6301 ggccaggacc tataacaatt atattaaata aaaaagatat aattccatac aaaactagtg
     6361 gagggcttga tacagttgca ataaggatgc cttctaatgt tattgccagg gcaataataa
     6421 aagaagctgg tatacctatt gcagctcctt ctgcaaatat ctcaggtcgc ccatctccaa
     6481 caaaagcaaa acatgtatat gaagagatga atggaagagt ggatggaata gttttaggag
     6541 gagacagtaa ttttggattg gagtcaactg tattggattt aacagaagag actcctatga
     6601 tactgagacc aggaagtata actaaagaag ttttagagga acttcttgga gaagtaaagc
     6661 ttgacccatc attaagtaaa aaagaagata atcaaaaagc taaagctcct ggaatgaaat
     6721 ataaacatta ttctccaaat gcagatgtat atataatatc tggaaaaaga gaaaatgtag
     6781 caacaaagat taatgatatg ataaaatcta atagagacaa aggtctaaag acaggtgtaa
     6841 tgtgtattag tagaaaccga gagttttatg atggagaagt aatcgattta ggaaactctc
     6901 ttgaagaagt tgcaagtaat ctgtttgatg ctcttataga aatggacaaa aagggtgttg
     6961 atgtcatata ttcagaagag ttccctaaga ctggagttgg acaagcaatt atgaatagac
     7021 tactgaagtc agcaggatac aaagtgataa aggcttaaga gggagttgta aaatatgaat
     7081 atacttattg tgtgtacagg taatacttgt agaagtccta tggctgaggc tatactaagg
     7141 aaagcaatta aagaatctgg aagaagtatt gaagaatatt ctatatcatc agcaggtata
     7201 tctacagcaa atggaatggg tgcttctgaa aattctatag aagtactaaa agaaatcggt
     7261 atagacttat caaatcatag aagtaaagta attactaaaa aattaattga tgaatcagat
     7321 ataatactaa caatgactaa atctcataaa gaaattttag tacaagcagt tccaaaatgc
     7381 aaagaaaaag tgtatacttt taaagggttt gcaaataaaa atgaggaaga tatatctgac
     7441 ccatttggtg gaaatttgga tatttataga agcactatga gagaaataat gtattctgtc
     7501 aacgaaatag taaaaaaaat atgaaacgga ggataaacaa atgaagatag gattaggctg
     7561 tgaccatgga ggatataatt taaaaaaaga aataataagc tatttagaaa gtaaaggcat
     7621 agaatgtgta gattatggaa ctaataatgc tacagattct gttgattatc ctgtttatgg
     7681 agaaatagtt gcaaattcag ttataaataa agaagtagat tatggaatat tatgttgtgg
     7741 tacagggata ggaatatctt tagctgctaa taaggttcct gggataagat gtgcagttgt
     7801 atcagatgta ttttctgcaa aaatgtcaaa agcacataat gatgcaaata tgttatcatt
     7861 aggcgaaaga gttttaggaa aaggtctagc acttgagata gttgaagcat ggattaatac
     7921 ggattttgaa ggtgatagac atgctagaag agtaaacatg attaaatcaa tagaagaaaa
     7981 acataataaa taataaaaat tacagtttta tcaggaggaa ttatcaaaat gagcaaagtg
     8041 gtagagacaa accatccatt aatacaacat aaattaactt taatgagaga taaaaatact
     8101 ggttctaaag actttagaga gcttttaact gaaattgcaa tgttaatggg gtatgaaata
     8161 acaaaagata taccattaaa agatgtagaa atagaaactc ctattcaaaa aacatcatct
     8221 aaagtagttg caggtaaaaa attagcaata attccaattt taagagcagg tcttggaatg
     8281 gtagatggat tagtgagctt aatgccagca gcaaaagttg gacatgtagg actatataga
     8341 gacccagaaa cattaaaacc agttgaatat tattgtaagc ttcctcaaga cataggagaa
     8401 agagatataa tagtagttga ccctatgctt gcaacagggg gttctgctgt agcagctata
     8461 gatttactta agtctaaagg agctaaaagt ataaaattag ctaatttagt agctgcacca
     8521 gaaggtatag cagaagtgca aaaatatcat gatgatgttg atatatatgt tgcatcagtt
     8581 gacgaaagat taaatgaaca tggatatata attcctggtc ttggtgatgc tggagataga
     8641 ttgtttggaa ctaaataaaa ataaataact ataaatattt attagggact ttcttatata
     8701 gtgtatataa ttttatgtaa gaaggttctt ttttatatat tttttctcaa aataggaatt
     8761 attgaattga taaatttctc gaattgagaa taaaaagttt ttaccaatta aaaaagattg
     8821 cttattttac aaggttttat agaatagtag tctattttaa tgtggcatgt tagttgctta
     8881 cgattaagat tataggtatt aagtgtatta gttaaattga gaattgaata ttaataatat
     8941 tattgggagt ggtaatacat gaagaattgt atagtagtaa gaggggctgg agatttagca
     9001 acagcagtta ttcataaatt acacaacagt ggttttaaag tagttgcgtt agaaatagaa
     9061 gagccattag ctataagaag gcaaatttct ttttgtgagg ctgtttatga aaaaaaagta
     9121 actgttgaag gtgtagaatg tatattttgc aatactgaaa aagaaataga agaagtttta
     9181 tctcaacata aagtagcctt gattatagac ccaaaaggag aaaaattatc taaattaaat
     9241 ccaatcgttt tggttgatgg aatactcgct aagaaaaact taggtacaac taaagatatg
     9301 gcaccactta caatagcttt aggtcctgga ttttgtgcag gagaagatgt agatgttgtt
     9361 atagagacaa tgagaggtca taatctagga agaataataa ctaatggtag agcagaaaaa
     9421 aatacaggag taccaggagc aataaaaggt ttttctaaag agagagttat gcattcacag
     9481 tatgatggca taatggaaaa tgtatgtaag ataggtgata tagttgaaaa gggagaccta
     9541 ctttgctata ttaataatta tgaaaaaaaa catgaagtta gagcaacaat atctggagtc
     9601 cttagaggtt tattaaagga tggagcaaag gtaaacaaaa atttaaaaat actagacata
     9661 gaccctagaa aagaagaagt taagaatgct tttacaatat cagataaagc tagatgtata
     9721 gctggagggg ttttagaagc catactaaac aatgggattt atccccaaaa ttaatttata
     9781 ttagataaag ctattaatat tttattaaga tgatataata aatttaatag attaaagaga
     9841 gcatatgacg ggtatttaaa atttaaatgg taaaaatgct ctttttttat tggacattca
     9901 attaacatgt gtatataata taaaaataag tatttattta ggttgaaatc taataaatat
     9961 ataataccag tacataagca aagaggagaa aagtaaatta tgagaccatc atgggatgaa
    10021 tacttcatgg aaattgcaga agtagtgaaa aagcgttcaa cttgtattag aagacaagta
    10081 ggagctgtaa ttgtaagaga caaacaaata ttaacaactg gatataatgg ttctccgaga
    10141 aatcttgaac actgtgaaaa tattggatgt aagaggcagg aattaaatat tccctcagga
    10201 gaaaggcatg aattatgcag agcattacat gctgaacaaa atgcgataat acaagctgct
    10261 cataatggta ttagtgtaga tggggcaact ttgtatgtta ctacaagacc ttgtgttttg
    10321 tgtgcaaaaa tgtgcataaa tgcaggtata ttgaaaattg tttatgaagg tgattatcca
    10381 gatgatatgt ctacagaatt attaaaagaa gcaggaatag aactcataaa attttagtgg
    10441 ataaaattta tatgacaata aatgtcaaat tatgacactg aaatacaatg gtatcaaatg
    10501 attaaaagaa agtatttgaa aaatcatcag attagtagta agatatattt tataattaaa
    10561 taaatttatg agatagatta attacatgtt atttatttta taataatgag ggatactatt
    10621 tatgagtaaa agaaatacac atacagaaat tgcaaagttg tttagtttaa taagccaaat
    10681 aggattgatg attgtaatat caatattagg atgtactttc ttaggaaaat ttttagatag
    10741 taaattgaat actactccag ttctgacaat aatattttta ttgttgggtg ttggaggtgc
    10801 ttttagtggt gtttataaaa ctctaatagt atatacacga aggaagtgat atattggata
    10861 taaaattact taaccaggta aggtcagtaa caaaaggtat agtaatattt gatgtagttt
    10921 taattgtgct aatgttgata acatcaacat taagtaaacc agtattatta ggacttatat
    10981 ttggctctat aatagctatg ttaaatttta gattattggc gatatcactg gaaaaatcag
    11041 tgacatttcc tgctgggaag gcacaagctt atgcatcagc acaatatgct gttagattat
    11101 ttataatggc agttgttcta attgcatcag ctacagtacc acatttaaat ataatcggaa
    11161 cagcattggg attattgagc acaaagtttg tcatattatc aaaaaacttt ataaataaat
    11221 taaagaggaa ggaggcataa gtatgaatca agcgcattat tatctcatag gaaactttaa
    11281 gattagtgaa acaatactag taagttgggg aataatggcc tttttagcga tagcatctta
    11341 ttttttgact agaaacttaa aaaaagttcc aactagtaaa gttcaaatat tcttagaatt
    11401 tgcagtaggt ggtcttgcta aaatggttac agatgttatg ggtaaaaata cagtaaaaag
    11461 aatgccatat atgataccat acataggaag cttgttttta tttttcgcat gttcaaattt
    11521 aagcccatta cttggattaa ggtcaccaac aaccgactta gatacaactg ctgcatgggc
    11581 aatgattaca ttttttatga tttattttgc aggagttaaa tttaaggggt tatcatactt
    11641 taaagaattg gctcaaccac ttgccataat gttaccaatc aatattatag gtgagttagc
    11701 tagaccaata tcattaagtt tccgtccatt tgggaatatt ttaggtggaa caataataat
    11761 gggtctgttt tatcaacttt taggttttat ttctagttta ataccaggat tatcaatacc
    11821 aattggagaa atattaatac cagtcccatt acacttgtac tttgacttat ttgcaggatt
    11881 gttacaagca tatatattta taatgttaac aatggtattt atatcaagtg caggagagtt
    11941 agattaagaa atcaacttat attaagataa aaataaaata atttaaaaaa ttaaagtttt
    12001 aaggaggaaa taattatgga aacagcaata gtagcggcag catcagcaat aggagcaggg
    12061 atagcagttg caacaggtat aggtgcaggt ataggtcaag gtatagcagc agctaaagct
    12121 gcagaagcag taggaaacca gccagaagct aaaggtgata taacatcaac tttattacta
    12181 ggagttgcta tagcagagtc ttcagcaata tatggtttgg ttatatcaat aatacttcta
    12241 ttcgtaaatc cattctttaa atacttagga atgtagattt agtccttaaa tattttgaga
    12301 taggtttata ggtaaatcat ctcaaactta taatcatgag atgaacttta tcatctcgtg
    12361 attataagta gttatgattt atggaaagga ggataattat ggaaaaagca ctagtaggta
    12421 taacgtggga atttgtgttc caaattgtta atacttttat aatattttta cttctgagaa
    12481 agcttttatt caagccagta ttaaatataa ttgaatcaag agaaaatgat attaaaagtg
    12541 atttggtaga aggcgaaaaa gcaaaaaatg aaggtttagc tctgaaaaaa gaatatgagt
    12601 caaaaatcaa ttttgccaaa gatgaaggtc aagaaatcat aaaacaagca actataagag
    12661 cagagcagaa atcagatgat atagtaaata ctgcaaagaa agatgctctt gatataaaag
    12721 aaaaagcaaa caaagatata gaacaagaaa gacaaaaggt tataaatgaa atcaaaaatg
    12781 atatatctaa catagcacta cttgcagcat ctaaagttat tgaaaaagat ttagataaat
    12841 ctaaacatga agaattgata gaaaacttta taaaagaggt aggggaagct aaatgataaa
    12901 tgtaatagca aatagatatg ccgaagccct atttcaatta ggagaagaag aaaattcaac
    12961 tgatgtctta ttcaaagaac tagaaaaagt agtagatatg atgactaaag ttagtaaaga
    13021 tttctacaaa gttttaaaat caccattagt ttcaaaatca gaaaagaaaa acttggtaga
    13081 aattattttt agtaaagaag taagttctaa cataaaaaac tttttaaaag ttttagtaga
    13141 taaagataga atatcatatt tagaagatat cgaattagct tataaagaat tattaaataa
    13201 gaaaaacaat gtaattgatg gagtagcaat aagtgctatt ccaatgagtg aaacagatat
    13261 taaagaactt gaagtcaaac tttcaaataa atacaacaaa aatgttacta tagaaaatgt
    13321 tgttgacaag actatactag ggggagttct agttagaatt ggaaatgaac aaatagatgg
    13381 cactgtgaaa actcgtcttg ataagatgaa agaaaagcta tctgaagtaa tatcttaaga
    13441 atggcggtga acccatgaac ttaaaacctg aagaaataag ttctataatt aaacagcaaa
    13501 taaaaaatta tgagaataaa gttgagttga cagatacagg tagtgtttta acagttgggg
    13561 atggtatagc gagtgtatat ggattagaaa aagctatgtc tggtgagttg ctagagttcc
    13621 caggtgaaat atatggtatg gcacttaact tggaagaaga agtagttgga gctgttatcc
    13681 ttggagatga cagtgaaata aaagaaggcg atatagttaa gagaactgga agaatagttg
    13741 aagttccagt tggagaagct ttaataggta gagttgtaaa ctcactaggt cagccaatag
    13801 atggaaaagg acctatagcg tacacaaaaa ctagaccagt tgaatctgag gcacctggta
    13861 taatagatag aaggtctgtt tatgaaccat tacaaacagg aatcaaatca atagattcaa
    13921 tgataccaat tggtagaggt caaagagagt taataatagg tgacagacaa actggtaaaa
    13981 catctatagt tattgacact atactaaatc aaaaaggaaa agatgttatc tgtatatatg
    14041 tagcaattgg acaaaaacgt tctactatag ctcaattagt tagctcttta gaaaaaggtg
    14101 gagctttgga ttatacaata gtagtttcag caacagcatc tgaatcagca ccacttcaat
    14161 atatagcacc atatgctgga gcagctatgg gtgaagaatt tatgtacaat gggaaacatg
    14221 tacttatagt gtatgatgat ttaagtaaac aagctgttgc atatagagaa atgtcattgt
    14281 tacttagaag accaccagga cgtgaggcat atcctggaga tgtattctat ttacattcaa
    14341 gattacttga aagagcagct aagttatctg atgaattggg tggaggttca atgactgcct
    14401 tgcctataat agaaactcaa gctggtgacg tttctgcata tataccaaca aatgttatat
    14461 ctataacaga tggtcaaata tacttacaac cagagttatt ctattcaggt gtaagaccag
    14521 cagttgaccc tggtatatca gtatcaaggg ttggtggttc tgcgcaaatt aaagcaatga
    14581 aaaaagttgc aggaacatta aaacttgcat attcacaata tagagaactt gcagcattct
    14641 cacagtttgg ttctgactta gatgaagata ctaaaaagag acttgctcaa ggtgaaagaa
    14701 tcgttgagat attaaaacaa ggtgagcatc aaccaataaa agttgaaaat caagttatga
    14761 taatatatgc tgttataaat aatcatttag aggatattcc gatagataat atagctagat
    14821 ttgaatcaga attgtatgca tttgtagata ataattatcc ggaaatatca agaaaaatat
    14881 taggtggaga agacttcact catgatttaa cagatgcaat aaatgaattt aaagaaaagt
    14941 ttgttgttga agtataatcc tttttaaaaa aggaggtaaa ttaattggca ggagctggaa
    15001 tcaaagcaat caaaacacgt atgggaactg ttgaaagtac aaagcaaata actaaagcaa
    15061 tggaattagt tgcatcttct aagcttagaa aagcaaaaga aaaggctgaa gattcaagag
    15121 aatattttaa tactttatac aatacagtaa aagatattgc ccaaacaaca cgtggaatta
    15181 gaaatgaatt tttaaaagaa agagaagtaa aaaataaatg ctatgtagta gtagctggag
    15241 acagaggact tgcaggtgga tacaattcta atgtattaaa ggaatctgtc tctcatatga
    15301 aaggtaaaaa ggaaacagtg attactgttg gaaagaaagc acatgaattt ttttctaaaa
    15361 gaaactacaa tatagcaaaa gatataaata gtgttgaagc ttgtggatat gaagatgcga
    15421 cagaaatttc acaaactatt attgacctgt ataaaaaagg tgaagtagat gaagtttata
    15481 ttgcttatac aaaatttaaa tctgctttat cacaagaagt tgaaattttg aaattgcttc
    15541 cattagtctt tgaaaaagat acagacgaac aaggaatggc agtaaaagaa gaaaaacaaa
    15601 atagatcaaa agtacaatat ataccatcag cagaagcagt tttaagttat attgtacctc
    15661 agtttatatc aggtacagta tatggtggaa ttttggaatc ttttgcatca gagcaaggtg
    15721 ctagaagaac tgcaatggaa tcagccacag acaatgcgaa tgaaatgcta tctaatttag
    15781 agttaagtta taacagagca agacagtcag ctgtaactca agaaataaca gagatagttg
    15841 gtggagttga agctctaaaa tagggaggtt aggaaatggc aaatgtaggt aaagtagtac
    15901 agattgtagg agctgtacta gatgttaagt ttgatagtga acaaagccta cctaacttat
    15961 taaatgcgtt agtaataaag ttaggagata aagaaatagt tgcagaagtt gctcaacata
    16021 taggtgatga tactgtaaga tgtatagcta tgagtgcaac agacggactt gtaagaggta
    16081 tggaagttgt agatacagga gggccaataa gtgttcctgt tggagatgaa actttaggta
    16141 gaatattcaa tgttcttgga aaaccagttg atgggaaacc agctccaaaa tctgcaccta
    16201 aattacctat acatagacca gcaccggcgt atgatgaact agaaactaca gcagagatac
    16261 tagaaactgg tattaaggta gttgacttac tagctccata tctaaaaggt ggaaaaatag
    16321 gtctatttgg aggagcagga gtaggaaaga cagttctaat acaagagctt ataaacaata
    16381 ttgctaagca acatggtggt atttctgtat tttcaggagt aggagaaaga acaagagaag
    16441 gtaacgacct ttatggcgaa atgagtgagt ctggagttat aaataaaaca gctctagtat
    16501 ttggtcaaat gaatgaacca cctggagcga gaatgagagt tgctttaact ggacttacaa
    16561 tggcagaaca ttttagagat gagcaaggac aagacgtttt acttttcgtt gataatatat
    16621 tccgtttcac acaagctggt tcagaagttt cagcacttct aggacgtatg ccatcagctg
    16681 ttggttatca gccaacatta gctactgaaa tgggtgcact tcaagagaga ataacatcaa
    16741 ctaagaaagg ttcaataaca tctgttcaag cagtatatgt accagcagat gacttaactg
    16801 acccagcacc agctacaaca ttctctcact tagatgcaaa aacagtttta tcaagacaaa
    16861 tatcatcact gggtatatat ccagcagttg accctcttga atctacatca aggattcttg
    16921 accctagtat agtaggaaaa gaacattatg aagtagctag aggtgtacaa tcaatacttc
    16981 aaagatataa agaacttcaa gatataattg ctatacttgg tatggatgaa ttatctgatg
    17041 aagataagtt aatagttgca cgtgctagaa agatacaaag attcttatct caatcattca
    17101 cagttgctga gcaatttaca ggaaatccag gtcaatatgt tcctgttaaa gagactgtaa
    17161 gaggatttaa agaaattctt gaagggaaac atgatgactt accagagtca gcattcttat
    17221 ttgtaggaac aatagaagac gctgttagaa aagcgaaggg aagtatgtag tcatggccag
    17281 tgaattttca ttgaaagttg taactccaag taatactttt tatgatggag atgttgaaat
    17341 gatagtagtt agaactacaa aaggagacaa aggggtgttg aaaggtcata taccatttgt
    17401 ttcaggtata cctgtaggaa ctttaaagat aaaaaaagag ggaagtttta aagaggcgaa
    17461 aatagcagaa ggattcatta atgtaactca agataaaact gtcatattga cagaatctgc
    17521 tgagtggatt taataaatta atttagagta taaaaagtca ttttgaccaa aaaaactttt
    17581 gggtaaaatg gcttttttgt gttttggtgt taataaaata acgataaaat tgtaagtttt
    17641 tagtgataat aaattcacaa aatgtttaaa tttactgcca aattatgttg taattaataa
    17701 gataaagaag atttagatag cttttatgta agtgaaaaag tcttcatata agaaatacat
    17761 ataaaatttt tataaaattt aaaaaatttg cttagttgtg tagtataata aataatataa
    17821 tagatttgta tataatattc attacaaata attttaaaag ttacagtttt attataatga
    17881 ttattaaatt aagataagta acataaacta aataataatg tgtattatcg atagtaaatt
    17941 tataaattca ttattaatta ttgaaagaag tattataaat tttctggagg aacaatgaat
    18001 atatttgata ttggcgtaga tataattgaa attgatagaa taagaaaggc tgtagacaaa
    18061 aataataggt ttttggagaa gatatttaca gatagagaaa tagagtattt taattctaag
    18121 aattttaaag cagaaagtat agcaggtaat ttcgcagcca aggaagctat aagtaaatct
    18181 ataggtacag gaattagagt gtttaatttt aaagatatag aagttctcag agatgaaatg
    18241 ggaaaaccaa tagtaaaaac ttataataat ctagcaaaaa tgtgcataga ttataatgtt
    18301 ttagaaataa aagtttcaat atcacattca aaagattatg ctatagcaaa tgcgataacc
    18361 ataattaagg actaaggagt gattacatta tgatggataa aacagcaaaa gaaataatga
    18421 caacagatgt aatagtagca aaacaagatg atagtatagc agatgtagct aatatgctaa
    18481 ttgcagaaaa aataggaggt ctgccagttg tagattcaga gaatagagtt gttggaataa
    18541 tttctgaaac agatattctt aaaaaagaaa aatatataga agcacctctc tatataaatc
    18601 tattacaagg attgattttc ttagatgact taaaaaaagt tgaaaaagat ataaaacaag
    18661 tagctgctta taaggttgga gaacttatgt ctaaagatat aataaaggtt catgaagatg
    18721 ataagtttga tgatgtagct aatgtaatga ttaaaaaatc aataaacaga gttcctgtag
    18781 tagatgatga caacaaactt aaaggtataa tttgtagata tgatataata aaagctttat
    18841 acaatgaata aactgaagta ggaggtgtga tgtgagaaaa aagtggacca tagtatgtat
    18901 tatgttcttg gcactggtta taattgtaat aggatgccaa aaacgacagt ccacaaaaga
    18961 agaagtatac aaagattttc aaaagcagat ttctgatatg aattattaca gttgtaaagc
    19021 tgaagtagaa gtagttggaa ataaaagtcc acacaattat gttttaattc atacttataa
    19081 aaaaaccgat aactataaat tagaagtaat ttccccaaaa catttaaaag ggaaaagtat
    19141 agaatatcaa ggtgataaaa tattagttaa aaatccaaag attagtgatg tagtggagtt
    19201 acctaataca ggaaaaaata atcaatatct ttttgtagga gactttataa aaaactatct
    19261 tcaaaatgag gagatgaaag taaagttatc caaaggacat ttggttttag agacttttat
    19321 tcctggggat aataaatatt ttaacaagca agtattatat gtaaatgctg acacaaaaaa
    19381 tcctgaaaaa atggaagtgt tagataaaga gggagtgcca agatttacag taaaatacaa
    19441 agattttgaa tacagaaact aagggggact aaagacatgc aaaaaataac agtgcctaca
    19501 tgggcagaga taaatctaga taacttaaga tttaacttaa ataatattaa aaatttatta
    19561 gaagaagata ttaagatttg tggagtaata aaagctgatg catatggaca tggtgcagta
    19621 gaagttgcaa aattgctaga aaaagaaaaa gtagattact tagcagtagc aagaactgct
    19681 gaaggaattg aacttagaca aaatggcata acacttccta ttttgaactt gggatatact
    19741 ccagacgaag cttttgaaga ttctataaaa aataaaataa ctatgacagt ttattcttta
    19801 gaaacagcac aaaagataaa tgaaattgca aaatctttag gagaaaaagc ctgtgttcat
    19861 gttaaaatag actcagggat gactagaata ggtttccaac ctaatgagga gtcagtacag
    19921 gaaataatag aattaaataa attagaatat atagatttag aaggtatgtt tactcatttt
    19981 gctacagctg atgaagtaag taaagagtac acttataaac aagctaataa ttataaattt
    20041 atgtctgata aattagatga ggctggtgta aaaatagcta taaaacatgt atcaaacagt
    20101 gcagctatta tggattgccc tgatttaaga ttaaatatgg taagagcagg aataatatta
    20161 tatggtcatt atccatctga tgatgtattt aaagatagat tagaattaag accagccatg
    20221 aaattaaaat caaaaatcgg acatataaaa caagttgaac caggtgtagg aataagttat
    20281 ggactaaaat acacaactac aggtaaagaa acaatagcta cagttccaat aggatacgca
    20341 gatggattta ctagaatcca aaaaaatcca aaggttctta ttaagggaga agtgtttgat
    20401 gtagttggta gaatatgtat ggatcaaata atggttagaa ttgacaaaga tatagacata
    20461 aaagttggag atgaggttat actatttgga gaaggcgaag ttacagctga gcgtatagct
    20521 aaagacttag gaactataaa ctatgaagtg ttatgtatga tatcaagaag agttgaccgt
    20581 gtttatatgg aaaataatga gcttgtacaa ataaacagtt atttgctaaa ataaaaccat
    20641 gatattataa tctgggaggc gattttgtgt acgataagag taaagaaaaa atagaagtta
    20701 ctttacctga ctctctgatt tctgaagttg atagtatagt tcagatggag aacagtaaca
    20761 gagaagattt tgcaaaagct gcttttcagt tctatataac tcagaaaaag aaaattcata
    20821 ttaaagaatc tatgaaaacg ggttatagag aaatgggtca aattaatctg tcactagctg
    20881 aattaggtat gacagttgaa gaagtatctt ctgatgataa aaatgaaggg aagattgccc
    20941 aaggtgagta ctaattgtga aataaagcgt ggtgatttat attacgctga tttaagtcca
    21001 gttgttggtt cagagcaggg aggcgttaga cctgttctga taatacaaaa tgatgtaggt
    21061 aataaatata gtcctacagt tatagtatca gctataacat ctcagattaa taaagccaag
    21121 ttacctactc atgtagagat aagttccaat gaatatgggc ttaataaaga ctcagtaatt
    21181 cttttagagc aaattagaac tatcgataaa aagagactga gggaaaaaat tggttgtcta
    21241 gatgaaaata tgatgataaa agtagatgat ggacttcaaa taagtttagg attgtttact
    21301 ttttaaagag ggatttgtct tttattagac aatccctttt ttcttttaaa tatctcttaa
    21361 ggtttaattt taatgtacta tgttaataaa attaaaaata acgcaaaaaa atagcataaa
    21421 agtgatataa taatatggaa ttgatataaa attacgaact caagggaggt aattgcatga
    21481 gagaccataa aggattaaat gagattgcgc gtatcataag aagagatata gtttcaatga
    21541 tacatagagc caaatctgga catccaggag ggtcattatc agtagttgaa atacttactg
    21601 cgttatactt tgatgaaatg aatgtggatt cttcaaatcc taaaatggag gatagagata
    21661 gatttgtatt atcaaaagga catgctgcac cagcattata tgctacattg gctgaaaaag
    21721 gttattttga taaggaagaa ctgaatggat taaggaagat aggaaggatg ttacaaggtc
    21781 atccagacat gaaaggcacg ccaggtgtgg aaatatctac tggttcttta ggtcaaggtt
    21841 tttcagttgc atgtggtatg gctatggcat caaagttgga taatgctccg tggaatgtgt
    21901 atactttgct tggtgatggt gaggttcaag aaggaattgt ttgggaagct gctatgagtg
    21961 ctgcacatta taaacttgat aatttaattg cttttttaga taataatgga cttcaaatag
    22021 atggagatat agaaagcgta atgagtttag gttcaatagt tgataaattt aaagcttttg
    22081 gttggaatgt aattgagata gatggacatg attttgacca aatatttgcg gctcttgata
    22141 tagctaaatc aacagttaaa aaacctacaa tgatagttgc aaaaactata aaaggcaaag
    22201 gaatatcttt tatggaaaat caagcaggat ggcatgggac agctccaagt gatgaggagc
    22261 tagaaaaagc cttgcttgaa ttaggaggtg ctgacaatga gtaaaatggc gacgagagaa
    22321 gcatatggta aagcattagt aaaattgggt caaataaatg acaatgttgt agtattagat
    22381 gcagatttat caaagtctac aaaaacacat gatttttaca agtcatttcc agatagattt
    22441 tttaatatgg gtatagctga acaaaattta ataggcgctg cttgtggatt atcaactgct
    22501 ggtaaaatac cttttgcaag cacttttgct atgtttgcta cgggaagggc ttttgagatt
    22561 ataagaaatt cagtttgtta tccaaagcta aatgtaaaaa tatgtgctac tcatgcaggt
    22621 cttactgttg gagaggatgg agcatctcat gaaagtgtgg aagatattgc tataatgaga
    22681 gctataccaa atatgacagt tcttgttcca gctgatggag ttgaaacaga aaaaattatt
    22741 tttgaaatag ctaagtataa tggacctgtt tatgttagat tagggagaag ttcagtacca
    22801 gttttatttg atgaagatta taaatttgaa ataggaaaag gtacagtctt aagagaagga
    22861 aaggatgtat caattatagc ttgtggaatt atggtaaatg aagctctatt agcacaagaa
    22921 aagttgcaag aagaaggtat aagtgctaga gttataaaca tgtcctcgat aaaacctata
    22981 gacaaagatt taatattaga atcagcaaaa gaaacgaatg ctattgtaac tgtagaagaa
    23041 catagcataa ttgggggatt aggttctgct gtaagtgagg tagtaggaga gtcttgtcca
    23101 accattgtaa agaaagttgg aattaaagat acatttggag aatctggtac tccaaatgaa
    23161 ttgttaaaaa aatatgaatt aacttgtgat gacataataa agactgttaa agaagctatt
    23221 attgcaaaaa gaatgtaaga gatataaatt attcatgttt gttaataata taatatattt
    23281 aaaagagagg tataaagtgt tatattaatt tatatctctc ttttttttat atgatatcaa
    23341 tatatcaaaa atgtaataaa atattcaaat ttttacaaaa atagagaaaa tattcaaata
    23401 tatattgact attcagaaaa atatgactaa tatataattt atagagaaac taattttata
    23461 tataatgact acttagataa aagaatctaa aaaaattatg agaggaggag tagggtataa
    23521 aatcagatta taagttttaa gttattatac taaaaagcta taaaacagtt atcatgtatt
    23581 ttatgttaaa ggaaattgta ggtagtttat cgaattgttt aatcagaaga aaaaatttca
    23641 catggggagg taactgagat atgtcagaaa aagtaaatgt taaaacagtc atcagtttcg
    23701 caggtgcgta tgtagcaaca gtaatcggtt ctggatttgc aacaggacag gaaataatgc
    23761 aattcttctc tttttatggt tttgcaggta ttattggtgg gataatttca atggtattat
    23821 tctcatggat gggtgcttca gttatgtcaa aaggtaaaga gcttcaactt aaagaaccta
    23881 tcaaaattta tcgtgtttat tgtggtaagt atttaggaat attctttgaa tggtttggac
    23941 ctttattctt atttggtgtt ttcgtagtaa tgatttcagg agcaggagca actttaactg
    24001 aatactatgg attaaatcca tttgtaggta gagtaggtat ggcagtagta gcattattaa
    24061 ctgtttcact aggtcttgat aaattatcaa agatactagg tggaataggg cctataataa
    24121 taatctttac acttttagtt ggtggtataa gtttagctaa aaacataggt aatataggag
    24181 aagctgcaca agttcttagc actgtaaaga tagctaaacc agttccaaat gcctatctat
    24241 ctggtgtaat atatactact tataacacaa ttgttgttat ggcattctta actggattag
    24301 gagcaagtgc tgctaacaaa aaagaagcta tttgtggtgg tatattaggt ggagtagcac
    24361 ttatggctgc agctataatg atgcacttag ctattctttc tgatatagga aacttatatt
    24421 caaaagcaat accatcatta ttcttagcag ataagatttc accagtaatt ggagttttat
    24481 tctcaataat tcttatatta ggtatatata caacagctgt acctttatta tggtcagtaa
    24541 ctaatagatt tgtagatgac aaacatccta agtttaaatt aataacttta atagcagcta
    24601 tattaggtct tataggtggc ttcctaccat ttgataagct ggttggtatt ttatatccat
    24661 atactggata tatgggcgtc ataatactgg tttgtgttct ttatagacag attacaaaaa
    24721 catctggata tcaagaagga atcagtgaca aataagtatt ttttaatatt gtaaactcaa
    24781 gagctatatg aaaacaatga aaatgttttc atatagctct ttttattttt tagctcgttt
    24841 attatgaaat agaaaaaaca tgttttttag ttacattaca tatatttata attatgtata
    24901 aatatatact aatcaataat ttagagtcta agataagttt ataaatcata tatttagaat
    24961 atatgggagg agtgataaga ttgaatgtaa agtttaatat taaaggtata atttatggag
    25021 ttatagctct tgtattcgtt atagggggat ttatattcat accaagtatg tttgtagaga
    25081 aatctaaacc catagattat acagtattac aaagaaattc aataccagaa aagatattag
    25141 atgtgatgga taagtataca aatgaagaaa gagcattagc ggctaaaatc gataacaaaa
    25201 tatacattat agtgactaga ggaaataata aatatggtat agaaatggac aaaatagaaa
    25261 gtgtggttga ggaaggaaag gatgttttga gagtcaagat aaagtataaa gataaggaag
    25321 attcttttcc atacatagtt gttgaaacaa atatgagtga acttccagat agaatagaat
    25381 taaatgcgac gaaataagaa ggtattttat aattaaataa ctgcatattg tacaataaag
    25441 tcatggtttt tattaatgta agtaaattgt gtatggttct tattgttgta aaagccatga
    25501 cttaaaatgc ttataaagta agatattaac agtagtattt attactacat taaatggggt
    25561 ctggaaatac ttaatattct aactatttgg agtgataatt ctagtttcag taactatgta
    25621 gtctaattgt gcatcatgag tttcttttgg aatagaatcg aatatctgga agtcaaatgc
    25681 tatgccgata gttatagcat cttttcttaa gttttctaaa aatctatcat aaaatcctcc
    25741 accatatcct aatctatagc aatgtatatc atatgctaca gctggtacaa ttacaacatc
    25801 taaggcctta atatcaattg taggtgattt ttcgttaggt tctcttattc catatgctcc
    25861 aattctcaat ccctctttta aatctgttat ttgagtaggg attaatgtat gattttcttt
    25921 tattgtgatg ggacttgata ctattttctt tagagacaaa agttttttga ttaaattatc
    25981 tgtttgaact tcattgttaa aatttagata aagcattata ttagttgcat ttcttatatc
    26041 ttccatttga agtaattttt cagttattaa atttgaatta ctaagtacaa agtttgcatt
    26101 cttatttttt cttgattcaa taactttttt tctaaattct tttttcataa aataattcct
    26161 cccttaatat gttataatgt gtacagcaat tgtatttaat ataaatttta gtataattta
    26221 ttgtaataaa gcaatatatt tgggtaaatg taataaaaat aacagctagt catataataa
    26281 taatagttta tgtaaaagga gatgtatctt gtgatttcaa agaagaaagc tattttttta
    26341 ggggtgattt tagtaattat aacagctatg gttacatcag catttcagtt gacattgggg
    26401 aataaagttg taatatcgaa agaactctat gaagactata aaaaatatga taagttgtta
    26461 ggactagaat ctattataaa acaagatttt tataaaaaag tatcagatac tgatttggta
    26521 aatggagcag caaaaggtct atttctagga acaaatgata agtattctgg ttattatact
    26581 aaagatgaaa tggagaatct aattaatgat agtgaaggtt cttatgttgg tgtaggtatg
    26641 tatatagggg catcaaaaga tggtggctta gtagtagttc ccatgaaaga ttctccagca
    26701 gagaaagccg gtgtaaaatc aggggataaa ttagtaaaag tcaatggaaa atctgtctca
    26761 tataaaaatt cagatgaagc tgttcgtatg atgaagggta aaaaaggtaa aacagttgaa
    26821 ctgactatat taagagaaga taaacaattg aactttaaag taaaaacaga ccagataatt
    26881 gagaagagta tagaaagtaa agtaattgat aatgatttag gatatataga aattacccaa
    26941 tttatatcaa gtacatatac tgactttgat aaagctttaa aagaattaaa agcaaaaaat
    27001 atcaagggat tagtaataga ccttagaaat aatcctggtg gaatgctaga tatatgtaaa
    27061 gaagttgctg atgagttaat tggtgaagga actatagtat atacaaaaga taataaggga
    27121 aatactgagt acttgaaatc tgataaagaa aaattgggac ttccaatagt agtgttaact
    27181 aatggagaaa gtgcttctgc tgctgaaata ttaacagctg caatcgttga taataaagaa
    27241 ggtatttctg tagggactac aacttttggt aaagggttgg tacaatcagt tgtaagattg
    27301 aaggatggaa caggatacaa gctaactact gctcaatatt ttacacctaa tggggattat
    27361 atcaatgaaa aaggtataaa gcctactatt gaagagaaag atgaaaataa acagttagat
    27421 gtagcaacta agtggcttag agaacagatt gataaatagg atttaatttt tataaactta
    27481 tactataaaa taaagaacat tataaaagag atgtctcaaa atgaactttt tagttcatga
    27541 gggagtctgg aaatatttat gtgtattctt taaataaaaa tttatttttt aagtgataat
    27601 taaattttta cagacagggc tatggtttta aaaatcatag ccttattttg atatttttta
    27661 aaaacatatt gcaacccagt tgttccaaat attatatcat ttacttttaa aatatcgcaa
    27721 actgcatatt atatattcat tataatataa tttatctaa
//
LOCUS       DAEPKC010000049        26717 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.049, whole genome shotgun sequence.
ACCESSION   DAEPKC010000049 DAEPKC010000000
VERSION     DAEPKC010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 26717)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26717)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26717
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.049"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            583..1800
                     /locus_tag="KR294_002132"
     CDS             583..1800
                     /locus_tag="KR294_002132"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase"
                     /protein_id="HBH0240210.1"
                     /translation="MMNVTLTDVKEARETIKNIVKRTDLLESVKLSEKTGANVFYKCE
                     NLQKTGSFKLRGACNKIASLTDEEKANGVIASSAGNHAQGVALGAKMTGIKSTIVMPA
                     TAPLAKVSATKGYGAEVVLNGAVYDDAYAKAVEIQKETGATFLHPFNDKYVIAGQGTI
                     SLEIFEQLDNKVDTILCPVGGGGIISGVAVAAKALNPNVKIVGVQTANIPSMKESIKN
                     GKVTTAFNDTTIADGIAVKTPGDLTFEIINELVDEIVVVEETEIAESILFMMESQKIV
                     SEGAGAVCTAAILSGKYVPAKDENVVCIISGGNIDINTLYRIIGVALAKEGRRYSFST
                     IMEDKPGNFAELTRIISENGGNILSANQGKLSAGEALGKQSAEFILETIDYDHIARIK
                     KAIEEKGFKIIEL"
     gene            1895..2275
                     /locus_tag="KR294_002133"
     CDS             1895..2275
                     /locus_tag="KR294_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HBH0240211.1"
                     /translation="MKHEVIHTNDAPAALGPYSQAIKAGNLLFVSGQVPLVPETMEVV
                     EGDVQAQTAQSLKNLKAILAESGADFSNVVKTTVFIKDMNEFGAINEVYAEYFGENKP
                     ARACVEVARLPKDVKVEIEVIAVL"
     gene            2559..3041
                     /locus_tag="KR294_002134"
     CDS             2559..3041
                     /locus_tag="KR294_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBH0240212.1"
                     /translation="MLNFFKKNKSYKLHAVVSGNSINIEKVNDSVFSKKLMGDGVAII
                     PNSNVVVAPCNGKVTVLTESKHAFGMVSDEGVEILVHIGIDTVSLQGEGFKNEVSQGD
                     TVKKGSPIISFEREKINSQGIDCTTIIIVLNHSEFSEINCMVENEVVAGQDTVIEIMK
                     "
     gene            3062..3877
                     /locus_tag="KR294_002135"
     CDS             3062..3877
                     /locus_tag="KR294_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBH0240213.1"
                     /translation="MRVVKIFNNNALSTVTNDRKEAILLGLGIGFNKRPGDKVNEDKI
                     EKIYYVQDHMQTKFLELLKNVSPEVMDASQQIISLIPGNEGKFNNKGILSLVEHISFA
                     IDRMKNNVFLPNLMLLDIKMMYSKEFELGVKALEIIYRVCHIHLPEDEAGYIALHFVN
                     LQSNDNLAYDTLKFVKGSIDLIKECYGLELDESSLSTLRFRTHLKFLAQRIFKNEICQ
                     DDKMIEMYDYLINNHPKNKEYLEKLNVYIEKEFRYKLDKPEKIYLLLHLTKIL"
     gene            3930..5480
                     /locus_tag="KR294_002136"
     CDS             3930..5480
                     /locus_tag="KR294_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBH0240214.1"
                     /translation="MKEKLLGGLETFAKAMVQPLMYLSSAGILMVVGVLLTNDMLLGV
                     LPFFKWEPIQIFGSLIYNCIMAIINNLAVIFAIGIPAALAKKEKHKAALIGFMSYIIY
                     LTASNTMLTSLGQLAKESKMLGLIGTGQATILGIQVVDTSVFGGIILGYIAGYVFNRT
                     SNKTFKGALQIYSGANFSFICMFFVSILIGVVSNFIWPLAQQGIASLANVIKDTGTFG
                     LFLYGFLERILVPTGLHHLIYTPFQFSDLGGVLKVGADTVSGAYAIVMTEMNLPVERF
                     SDSIYYMATGFTKMFGYIGIGAAFIYTAYKQNKKKVKATIIPLIITAVLASVTEPLDF
                     MFVFCAPLLFFVHAVIAGLFIALLKIFDVTALCGGNLLVSVIMNTTVGVEKTHWPVMM
                     ILGLAQIIVYFVVFSFLIKKFNYKTPGREDESTATGEEQSKQLNLDAGIENIIDGLGG
                     KENINTVENCITRLRVNVKDESKINEDIINLTPNSGIVRKGKDIQIIFGLHVHEVRRA
                     VEDFLEAY"
     gene            5577..6929
                     /locus_tag="KR294_002137"
     CDS             5577..6929
                     /locus_tag="KR294_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HBH0240215.1"
                     /translation="MIITIVGGGSTFTPGIVKSIALREKELELEEIRLFDIDKKRQDK
                     VAVVVNWILKEDVKTDVKLTVTNCEKEAYTDATFIFAQMRVGKYEMREQDEKIPLKYG
                     CVGQETCGCGGMAYGLRTIQPMIKVIDDVEKYAKKDYWILNYSNPAAIVSEACRKLRP
                     NARIINICDMPIAIIDMIAGSLNINDVHNIRYDYFGLNHFGWFTSIDYKHRDLMEEIK
                     EYIKENKILLPKSYIENLNKSRSTGNRHAVSSWIHVWESVYTMLESFPKYLPNTYLTY
                     YLLSKETVEHSNINRTRANEVMESREKDLFEGVRHYLETGEISEKAFYAGSHGDWISD
                     LAVSIKNDTRSRFLVITENRGAIPNMPYDAMVEIPAYIGKDGPEVIARGPIPLFQQGL
                     MMQQLNSEKLIVEAYIENSYEKALQAFTLNKTIPSMNVAKEILDEMIEVNKEYWPELR
                     "
     gene            7060..7818
                     /locus_tag="KR294_002138"
     CDS             7060..7818
                     /locus_tag="KR294_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0240216.1"
                     /translation="MNIINKIFWQEDRIGMITNNLEADTHSHCMLQLFLGIEDSIEIT
                     VNEKLVKCNCIIVDKNISHSFSARKKVYYSAIIEPTSIYAEQLTSKMNDFGYWICDND
                     GLEKLRQQGTFLISNSSKEQYLRFMEMLNNYLNIPITLKHYDDRITELFNLLHTCNCD
                     NHTISSFADKVSLSASRLSHLFKEQIGIPLKSYILFHQMECAFRELLSGKNVTEASMT
                     AGFDTPSHFAGTVKRMMGMPVSLSLKDSEFLKVY"
     gene            7865..8584
                     /locus_tag="KR294_002139"
     CDS             7865..8584
                     /locus_tag="KR294_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="HBH0240217.1"
                     /translation="MNKEYLEETKMLNYNEPQLKLLVSSKNWLELDDFHKIKSIYEFV
                     QNDILFGYNASDMLSATQVLNDGMGQCNTKATLLMALLRAVNIPCRLHAFDVTKDFQR
                     GATSKLISLLAPKYILHTWVEVFYQDRWIALEGVITDKKYLEAIQKKFFNHGGTFKKY
                     AIATNDLKNTSIDWDGKDTFIQKEAIVYDYGIFPSPDVFFSTHSQHMSKLKNFIYVHL
                     IRKIMTKNVCKARNNYIDKNE"
     gene            complement(8708..10108)
                     /locus_tag="KR294_002140"
     CDS             complement(8708..10108)
                     /locus_tag="KR294_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HBH0240218.1"
                     /translation="METQSNNKKGNLIIAIVMTGAFISSLSQTLLSTALPNIMSDFKI
                     TADVGQWLTTIYLLIAGIIVPTTAYLINRFSTRKLFITSMSIFSIGCIIALFSNNFST
                     MLIARVLQAMGSGSLMPLLQVIILYLCPEEKRGAAMSLVGITVGFAPAIGPTLSGWLV
                     DSFGWHSLFLFLSPIAILDVILSFILLRNVGETQKLKLDIPSIVLSSLGFGGLLIGFT
                     NQGNYGWTNIATYLPILIGIMSLILFTLRQLKSKEPFLELRVFKNKPFLISTILIMIV
                     YASMMSATLMIPLYVQSVRGFSALSSGSLMLPGAILMVVLNPIAGRHLDKYGPHALSI
                     LGTGCLFLGTLSFAFLGRDTSLIHVSLMYCIRMIGISMVLMPLTTWGIKTLDRELISH
                     ATAINNTLRQISGAIGSAILITIMTSATKKAHMSSNMLSNIHGIDVAFSIAATLAFTG
                     LIVSICFIKRHQIIRS"
     gene            complement(10112..11020)
                     /locus_tag="KR294_002141"
     CDS             complement(10112..11020)
                     /locus_tag="KR294_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH0240219.1"
                     /translation="MKGDNKVTEKQRLIITIAQKIFDQKGFQNTSISDVVKECKMSKA
                     TFYKHFETKESFICEIINYYDEKFLEIIHSINENNDIPASEKLNRKIIAVWKNIFSRT
                     TINTYIRENFSEEQRKATSKLQTKSRANLLNEYKLSLFDNYGDKIEKIIFDLVFLLDA
                     LIHQFIYIIHVQKREINVYFIAKFTIQILDLVVENMDNLNPLIEKSMFLHKQEDEVYF
                     SLHNKSLFFKMIQDIEELIKTDTSLLENPKLLEAIKKLYVEGKNQQYDSLIMDAMIAY
                     LEKEDTLRPKVLLLNSIKNQLKKETL"
     gene            11281..11928
                     /locus_tag="KR294_002142"
     CDS             11281..11928
                     /locus_tag="KR294_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HBH0240220.1"
                     /translation="MKKKICVAIIFALFIVFVEMFIDSSSEGSKIMTAELSKYRKGVN
                     VLSINNIIVANKKYSLPKDYSPQESSEARDAFYKMNKDAQKSGLNLKAFSTYRSYEYQ
                     DRLFKSYVKEHGEKEANRFSAKPGESEHQTGLAFDIGGDDQSCWANKKFNNTKEAKWL
                     YENAYKYGFILRYPEGKENITGYMYESWHYRYVGTEHSKNFAMNNLTLEEYLHIN"
     gene            12252..14891
                     /locus_tag="KR294_002143"
     CDS             12252..14891
                     /locus_tag="KR294_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBH0240221.1"
                     /translation="MSYKSTYQEVIKNLDSSLSGLSKERAEELLEKNGANELKEADKV
                     PTYKLFLESFKDPLVIILLIAALVQIFLGETVESIIIFAVIIINSVLGVVQTKKAESS
                     LESLKNLSAPNAKVIRDNKKMTIPAKNLVVGDIVFLEAGDYIPADGRLIEAQSLKVVE
                     GMLTGESEPVLKHTEKISEDVSLGDQKNMVFSGAVVVYGRGSFVVTGTGMDTEMGKIA
                     GLLESAENKLTPLQQKIEDFSKKLGVGIVILALLIFIIQVARNYFMAGNGEMTQIILD
                     SFMFSVAVAVAAIPEALSSIVTIVLAVGTNSMAKKQAIIRKLPAVETLGSTSVICTDK
                     TGTLTQNKMTVVDYYMYGTNNDELDKEKVNYSYHAKLLTMVSTLCNDSHITSDGKEVG
                     DPTEVALINYSSKNDLDYDKLRSKYIRINEIPFDSDRKLMSTVNSIYGDYIMFTKGAP
                     DIVFSRCKYALKNGSKVDITDEIIEEYKHKNEEFSNRALRVLAFAIKDVPEEDFIPSI
                     DDEHDMTLVGIMAMIDPPREEVMDAVKEAKSAGIKTVMITGDHKTTAAAIAKEIGIME
                     EGDLALTGKELDALSEEQLYEKLENISVYARVSPENKIRIVKAWQHKNNITAMTGDGV
                     NDAPALKQADIGIGMGSGTDVAKDASAMVLVDDNFASIVNAVEVGRTVYSNIIKSITY
                     LFAGNLGAIVSIVFAVFAGWSNPFTALQLLFINLVNDSLPAIALGFEKSEKNIMNKPP
                     RHPDESILAGGTLKAVAIRGCIIGVVTIIAQYIGLQVSPELGVAMAFSTLILARIMQT
                     LPARSNNQTVIKLGFFSNKYVIGAVLVCLGLYSLTLIPVLRGIFSIPTTFGLYQLGIC
                     LGLALISSILMELNKLINRSEVK"
     gene            complement(14949..16052)
                     /locus_tag="KR294_002144"
     CDS             complement(14949..16052)
                     /locus_tag="KR294_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate aminotransferase family
                     protein"
                     /protein_id="HBH0240222.1"
                     /translation="MKLKINKAIEMQLKKSYAIESGHSEDVFEIDCGEGINTVSYSNK
                     AVEAFNALKFDMIRGYPHSIALKDNIVDYWKDFIALDTDRICLADGSIHVIYLLNRLF
                     IEKGDKVLGYSPQFSEYETDIKMHGATYDYVLLKKEDNFKFNEKEFIEKINPEYKVIY
                     IDNPNNPTGQIIHLSSIENIVKEAAKYDIAVMVDEAYGEYMPKENSAVKLLNNYDNVI
                     ALKTFSKGFGLAGLRAGYAVLPEQLVSPIKKISTPYEVSEISRSIAANLLDDVQFIEE
                     LKEKTKDIKNQLLIPWKNLNIAETSDTVSIMTVEHKNKDIDLQQEFAKLKIRVISGSD
                     FTGLDKNFIRFRMPEEKELPEVIKAFQIIDNIE"
     gene            16413..17234
                     /locus_tag="KR294_002145"
     CDS             16413..17234
                     /locus_tag="KR294_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBH0240223.1"
                     /translation="MGYKLIVTDMDGTLLGNNHKVTDENKTALQKVIKSGINVTLATG
                     RAFDSAKCNVDFLKEDMPIIACNGSLIREQNGNIIYSNKIDTRTCLNILDVLDKYDIY
                     YQCNSIDSMLSKKIEGREDRLSVFLGSETEVIVKDDLREEIFKKDILKFVIIEEKNPS
                     ILDEIRKELRKVQGIKITSSWPNNIEVMNEGVDKGNAVKILAEKMNIDREDIIAFGDN
                     YNDIEMIKFAGLGVAMGNAEELIKQEADYVTDTNQDSGVAKAIYKFLELKESLSS"
     misc_binding    17313..17524
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            17611..18927
                     /gene="argH"
                     /locus_tag="KR294_002146"
     CDS             17611..18927
                     /gene="argH"
                     /locus_tag="KR294_002146"
                     /EC_number="4.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012101354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HBH0240224.1"
                     /translation="MKLWGGRFRKAENQLMEEFNKSFGYDCVLYKKDIEGSVAHVHMQ
                     VKCGLLTEEEGKSITEGLKGILEDVENGKLVLDGEYEDIHSFTEINLIQRIGDVGKKL
                     HTARSRNDQVAVDMRLYAKEKANDLVGLISEFKATIKDVADKNPVMMPGYTHLQRAQV
                     VTFKHHLMAYYSMFDRDEKRIKNAIEILDESPLGCGALAGTTHDIDRSITCEQLGFKK
                     VVDNFMDGVSDRDYLLELMSDFSIIMMHLSRLSEELILWSSQEFGFVEIDDLYTTGSS
                     IMPQKKNPDGAELIRGKTGRVYGNLFGLFTVMKGIPLAYNKDMQEDKEGFFDSVHTLE
                     MCIQIMDRMIATLKVNEDKMKQAVKNGFLNATEVADYLVKNNVAFRDAHGIVGSIVIY
                     CEDNKKAIEDLTLEELHKFSDAFKEDIYDFIDYESILNKGIKKNLK"
     gene            19176..19514
                     /locus_tag="KR294_002147"
     CDS             19176..19514
                     /locus_tag="KR294_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2325 domain-containing protein"
                     /protein_id="HBH0240225.1"
                     /translation="MNLLVIGGHERMEKDYMVMAKKKGYKTKVYTTMSSKLNNSIGRP
                     DAVVILTSTVSHKMSRTVESQAKKQDILIVRHKNSSKVAFNECLDMVDECLGNCSKCK
                     LKDKQKQKNI"
     gene            complement(19641..20930)
                     /locus_tag="KR294_002148"
     CDS             complement(19641..20930)
                     /locus_tag="KR294_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HBH0240226.1"
                     /translation="MKRNLSLLLICLLIFTSFLGSSNISFADNEPAIVAKHAVLMDYE
                     SGKILYNKDGNSKLYPASTTKVWTACLVLKEVKDLNQVIEIKDLPQIDGSSMYLKNGE
                     SFTVKQLLDALLVHSANDAAFVLARYVGGGNVQKFIDLMNSEAKKIGATNTHFNNPHG
                     LPDPNHYTTAHDMALIAREAMNNDTFRQIVKTKSLKFEATKAYPYERYFVNTNKFLTS
                     HDKITYKGQPINIKYDIVDGIKTGYTDAAGKCLLSSAVKDGRRVIVAVFNSTNADLYL
                     DSRILIDYGFDNFKCATIVDKEKYTDTKKVLFTKQHELIYEPKNSYRIFLEKDESQGN
                     YDTKTELNKIDLPIKKGAKVGTLNVYNNGKLENSIDLIAKNNLDSSLPFFTGNNILMT
                     FVKIIAGILVLLVLFIIASNIKKKKRKKARSKKNMKK"
     gene            21010..21714
                     /locus_tag="KR294_002149"
     CDS             21010..21714
                     /locus_tag="KR294_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HBH0240227.1"
                     /translation="MKKKVKFISFFVLFILIISSIIVYKSLIFKDDIYVVSKKNLPNE
                     KTHVVENEIKGEDNNHNKVTKDIDKNFQNNKITIYISGAVNRPGIVTIESDKRLYDAV
                     ELLGGTTKEADLNGVNLSVRLEDEQHYIIPKIGEATSVTSNDDSNKPNQRNESRGEPK
                     NKSNKNISNESKVNINVATIEELDSLPGVGEATANKILQHREENGQFSSIEEIKNVNG
                     IGDKKYENIKDLICVD"
     gene            21806..22852
                     /gene="selD"
                     /locus_tag="KR294_002150"
     CDS             21806..22852
                     /gene="selD"
                     /locus_tag="KR294_002150"
                     /EC_number="2.7.9.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015617929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:21854..21856,aa:Sec)
                     /transl_table=11
                     /product="selenide, water dikinase SelD"
                     /protein_id="HBH0240228.1"
                     /translation="MKKEQKKLTEMTTAGGUAAKIGPEVLASVLSQLPKNDNIENLLV
                     GLDTADDAAVYKLNDDMALIQTLDFFTPMVDDPYVFGQIAASNSLSDVYAMGGKPLVA
                     MNIVCFPSCHDMDVLAEILKGGFDKVKESGALLVGGHTVDDKEPKYGLSVSGIVSPNK
                     VLSNATAKPGDKLIITKPIGVGVLNTAMKEGMVEQHIADKVIEIMIHLNKYAAMSFEK
                     FDVNSVTDITGFGLLGHTLEMAKASEVSIEIESKHVPIIEGAIEMAQMGIIPAGMYKN
                     MHYVSKDVEVVGNIEVAVQDILYDPQTSGGLLISVKEELAEELVKDMKLNGAIEAKII
                     GSVVPKGEKYITVL"
     gene            22870..24282
                     /locus_tag="KR294_002151"
     CDS             22870..24282
                     /locus_tag="KR294_002151"
                     /EC_number="2.9.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-seryl-tRNA(Sec) selenium transferase"
                     /protein_id="HBH0240229.1"
                     /translation="MIVLSKRELFAMLPSVDEVLSDNRIVEIINEYPRSLVLESVREV
                     IDLKRQFILRLKEDASNSVTIEFGEIIESAIERVKLNYSLSLKKVINATGTVIHTNLG
                     RSLLSEDIKDELWCAASRYSNLEYDLDNGERGSRYSHLTSTIKRLTGAEDVLVVNNNA
                     AAVLLVLSTMAKGGEAIVSRGELVEVGGSFRIPSIMALSGAELVEVGSTNKTHLKDYK
                     EAITEDTNVLMKVHTSNYRIMGFTESVSIEELVNLGKKYKLPVIEDLGSGVFIDLSKY
                     GLSYEPTVLDSIRQGADVVTFSGDKMLGGPQAGIIVGKKEYIEKMKKNQLTRALRVDK
                     LTICALEATLRMYLDETKAIENIPTLKMLTYKIEELEVKANKLFEKITALNLNANINI
                     EDGFSQVGGGSMPLETISTKVISITPEHMNVSSLEKKLRLSEAHIIARVYDNKYVLDV
                     RTIFDDEFDVIVEELRKAFN"
     gene            24396..26279
                     /gene="selB"
                     /locus_tag="KR294_002152"
     CDS             24396..26279
                     /gene="selB"
                     /locus_tag="KR294_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenocysteine-specific translation elongation
                     factor"
                     /protein_id="HBH0240230.1"
                     /translation="MKNVVIGTAGHIDHGKTTLIKALTGRETDTLDEEKKRGISINLG
                     FTYFDLPNNRRAGIVDVPGHEKFIKNMLAGASGIDIVLLVVAADEGVMPQTVEHLDIL
                     SFLNIKNGIVVLTKSDTVDDEFRELVKEDICEKIKGTFLEDAEIIEVDSISKRGIDTL
                     IEKIDKMSDDIEDKNENSPARLNIDRVFSIKGFGTVITGTLIEGKISIEDDLVIYPQV
                     LKTKIRSIQVHGENKDTAYAGQRTAINISNVKVDDIKRGDVLAAPNSLEESMMLDVKL
                     SLVNHLDKGLKHWDRLRLYHGTREILCRAVPLDKELIESGESGYVQLRLEESIVSKKG
                     DTFVVRRYSPMETIGGGVIIDPSPKKHKKFDEKVIEALKIKEKGELKDIIEEYLKRNL
                     KNYPNIKEIMSYSGAHEEDVKRALETLISEDKVFIIGNMYMHINQYNKLKENTIKLLS
                     EYHKKYRLRKGILKEEVRSKIESNFKTREMDILLEKLSTENAIKIENNIVSLLDFEVI
                     LNDKQKEIAKKIEKRLKSCGVSSILTIDEVSEGNHNYAEVLESMIGNKVEKLDDLYIM
                     DKDIYENAKNILINYIKENKEITLGEYRDLIDSSRKNCMIILENFDRNKITKRVENKR
                     ILF"
     gene            26384..>26717
                     /locus_tag="KR294_002153"
     CDS             26384..>26717
                     /locus_tag="KR294_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HBH0240231.1"
                     /translation="MKNIIPDVKPDIKEREDMSLLFIIMGSVLLLFIIKDIEKYETLL
                     HAIYTIFLVATGVIIFNTTKFKVDSFSTFLGLIFIATGVLECIYLFNSLGIKTKSIME
                     INITISAIT"
BASE COUNT        10401 a         3006 c         4671 g         8639 t
ORIGIN      
        1 attataatag gtttatagaa aaagtaaagt atgaaattaa aataataact ctatttagcc
       61 ttattaaata tatgttaaaa taaaaaatac cttttaataa aaaatgattg ttatataaaa
      121 taaatattca atttaattat caccttagtt tttttattgt attttattat atatgtatag
      181 ttttctaatt ttgaataaaa ataaagtaaa actttctttt atattgaagt tgtttagtaa
      241 gatatgtatt ttattaattt attaatctta ataatgttaa ataaaatcaa aaaaatagat
      301 tttgggtaaa taaaataata taaaatataa attttaataa aaataataaa gtatatatta
      361 ttgctttaat aagaatgtaa aaaatatttt taaattatca tttaatgtaa tttaaatgaa
      421 ttgaagatat atgtttattg tatgcaattg ttgtattttt aggttttttg tgattaatta
      481 aaaaattata aaaatcgttt acatgttgat ttttaaaaaa aaaagatata gaattatata
      541 gaaagtaata aacaaaaatt ggatttacgg gagtggaatg aaatgatgaa tgttacctta
      601 acagatgtaa aagaggctag agagaccatt aagaacatag taaaaagaac tgacttactt
      661 gaaagtgtta aacttagcga aaaaacagga gcaaatgtgt tctataaatg tgagaatctt
      721 caaaaaacag gttcttttaa attaagagga gcttgtaaca aaatagcgag tttaacagat
      781 gaagaaaagg caaatggagt tatagcttca agtgcaggga atcatgctca aggagttgca
      841 ttgggagcaa aaatgactgg tataaaatct acaatagtaa tgccagcaac tgcgccttta
      901 gcaaaagtta gtgcaactaa aggttatgga gcagaagtag ttttaaatgg tgcggtttat
      961 gatgatgcat atgcaaaagc tgttgaaata caaaaagaaa caggagcaac tttcttacat
     1021 ccattcaatg ataagtatgt tatagcagga caaggaacta tatctcttga aattttcgaa
     1081 caattagaca ataaagttga tactatacta tgcccagttg gtggaggagg aatcatctct
     1141 ggtgttgctg ttgcagcaaa agcattaaat cctaatgtaa aaatagtcgg tgttcaaact
     1201 gcaaatatac cttcaatgaa agagtcaata aaaaatggaa aagtaacaac agcatttaat
     1261 gatactacaa tagctgatgg tatagctgtt aaaactccag gagatttaac ttttgaaata
     1321 ataaatgaat tggttgatga aatagtagtg gttgaagaga cagaaattgc agaatcaata
     1381 ttatttatga tggaaagtca aaaaatagtt tcagaaggtg ctggtgctgt atgtacagct
     1441 gctatattaa gtggtaagta tgtaccagca aaagatgaaa atgtagtttg tataatatct
     1501 ggtggtaata tagacataaa tacgttatat agaataatag gtgttgcttt agctaaagaa
     1561 ggaagaagat attcatttag tacaattatg gaagataagc caggaaactt tgctgagtta
     1621 actagaataa taagtgagaa tggtggaaac attttaagtg ctaatcaagg taaattatca
     1681 gcaggggaag ctctaggaaa acaaagtgcg gaatttatat tagagacaat agattatgac
     1741 catatagcta gaataaagaa agctatagaa gaaaaaggtt ttaaaattat agaattataa
     1801 taaaaagtgt atataatata caagaaaaat agtataatag tgtatgaaga tacattttat
     1861 gtgtattaga ttaacgaatt aggaggattt taaaatgaaa catgaagtaa tacatactaa
     1921 tgatgcacca gcagctttag gaccatattc tcaagctata aaagctggaa acttgttatt
     1981 tgtatctgga caagttcctc ttgtaccaga gactatggaa gtagttgaag gagatgtaca
     2041 agctcaaact gctcaatctt taaaaaatct taaagctata ttagctgaaa gtggagctga
     2101 tttttcaaat gtagttaaga ctacagtatt tataaaagat atgaatgaat ttggggctat
     2161 aaacgaagtt tatgctgaat attttggaga aaataaacca gcaagagctt gtgtagaagt
     2221 tgctagatta ccaaaagacg ttaaagttga aatagaagta atagctgtat tataaaaata
     2281 caatattttt aatttgaaaa ggctgaaaaa ctatattcta gtgattcagc ctttttataa
     2341 aaaaataaat cacaataaag aacatgataa atattgtcga attaaaaaat aaaattaaaa
     2401 taaatattgc aatatttttg agaaggtttt ataatgagta tataatttga aacgtgtaac
     2461 tattaaatta ggcatgagtt cttggatatt tttatcctga ggattcatgc cttttttgta
     2521 ttgaaattca aaaatctatt taataaggag gaagtactgt gttaaatttt ttcaagaaaa
     2581 ataaaagcta taagttacat gcagtagtga gtggtaacag cattaatatt gagaaagtaa
     2641 acgattctgt gttttcaaaa aagttaatgg gagatggagt tgcaattatt cctaatagta
     2701 atgttgttgt agccccttgt aatggtaaag taactgtgct tacagaatca aagcatgcct
     2761 ttggtatggt ctcagatgag ggtgttgaaa tattagtcca cataggaatt gatacagtta
     2821 gtttacaggg tgaggggttt aaaaatgaag tgtctcaagg agatactgtt aaaaaaggta
     2881 gtccaataat aagttttgaa agagaaaaaa taaattctca gggaattgat tgtacaacaa
     2941 taataattgt attaaatcat agcgaatttt cagaaataaa ttgcatggta gaaaatgaag
     3001 ttgttgcagg gcaagatact gttattgaaa ttatgaaata atagaaaggg attaattcaa
     3061 tatgagagta gtaaaaatct ttaataataa tgcattatct acagtaacta atgataggaa
     3121 agaagctatt ttactaggtc ttggtatagg ttttaataaa cgtccaggag ataaagttaa
     3181 tgaagataaa atagaaaaga tttattatgt tcaagaccac atgcaaacaa aatttttaga
     3241 attattaaaa aatgttagtc cagaagtgat ggatgcttca caacaaatta taagtcttat
     3301 accaggaaat gagggaaaat ttaataataa agggatatta tctttagtgg aacatattag
     3361 ttttgcaata gatagaatga aaaataatgt ttttttacct aatttaatgc ttttggatat
     3421 aaagatgatg tattcaaaag agtttgaatt aggagtaaaa gctttagaaa ttatatatag
     3481 agtatgtcat atccatttgc ctgaagatga agcaggttac atagctttac attttgtcaa
     3541 tttacaatca aatgataatt tggcatatga tactttaaaa tttgtaaaag gtagtattga
     3601 tttgattaaa gaatgttatg gattagaatt agacgaatcg agtttaagta cattacgttt
     3661 tagaactcat cttaaatttc ttgctcaaag aatttttaag aatgaaattt gtcaggatga
     3721 taaaatgatt gaaatgtatg attatttaat taacaatcat cctaaaaata aagaatattt
     3781 agaaaagtta aatgtatata ttgaaaagga gtttaggtat aaattagata aacctgaaaa
     3841 aatttatcta ctactacacc taacaaaaat cttataagaa tgagatgaat tagtaataga
     3901 aatatatata attttagggg gggataagat tgaaagaaaa actacttgga ggactggaaa
     3961 catttgcaaa ggcaatggtt cagccattaa tgtatttatc gagtgcagga atattaatgg
     4021 tggtaggtgt actacttaca aatgatatgt tattaggagt acttccattt tttaaatggg
     4081 agccaattca aatatttgga agcctaattt ataactgtat aatggctatt attaataatc
     4141 ttgctgttat atttgctata ggtattcctg ctgcactagc aaaaaaagag aagcacaaag
     4201 cagcgttaat aggatttatg agttatataa tataccttac agcttccaac actatgttaa
     4261 catcactagg tcaactagca aaagaaagca agatgcttgg actgataggg actggacaag
     4321 ctactatttt aggtattcaa gttgtagata caagtgtatt tggtggaatt attttagggt
     4381 atatagctgg atatgtattt aatcgtacaa gcaacaaaac atttaaagga gctttacaga
     4441 tatactcggg agcaaatttt agttttatat gcatgttctt tgtatccatt ttaattggag
     4501 ttgtgagtaa ctttatatgg ccattagctc aacaaggaat agcttctctt gcaaatgtca
     4561 tcaaagatac aggtacattt ggtttattct tatatggttt tttagagaga atattagtac
     4621 caactggact tcatcattta atttatacac catttcagtt ttctgattta ggaggagtgc
     4681 ttaaagttgg tgcagataca gtttcaggag cctatgctat agttatgaca gaaatgaatt
     4741 taccagttga gcgtttctca gatagtatat actacatggc aactggattt acaaagatgt
     4801 ttggttatat aggtatagga gctgccttta tttatactgc atataagcaa aataagaaga
     4861 aggttaaggc aacgattatt ccactaataa ttacggcagt attagcctct gtaacagaac
     4921 cattagactt tatgtttgta ttctgtgcac cacttttatt ctttgtacat gcagttatag
     4981 ctggtctttt tatagcttta ttaaaaatat ttgatgttac tgcattatgt ggagggaact
     5041 tattagtatc agttataatg aatactacag taggcgtaga aaaaacacac tggccagtaa
     5101 tgatgatatt aggacttgca caaattattg tatattttgt agtatttagt tttttaatta
     5161 agaaatttaa ttataaaact ccaggtcgtg aagatgagag tacagctaca ggcgaagaac
     5221 aatcaaaaca acttaattta gatgcaggga tagaaaatat aattgatggg ttaggcggaa
     5281 aagaaaatat taatacagta gaaaattgca tcactagatt acgtgttaat gtaaaagatg
     5341 aaagtaagat taatgaagat ataattaatt taacgccaaa tagcgggatt gtaaggaaag
     5401 gaaaagatat acaaataatt tttggacttc atgtgcatga ggtaagacgt gcagtagaag
     5461 attttttaga agcttattaa agatatatat ttatatagca agggtaaata acagctttaa
     5521 gtgctgttta ctatttatta aagatacata taatttatag aggaggaata attattatga
     5581 ttattactat tgttggtgga ggaagcacat ttactccagg tattgttaag tcaattgcat
     5641 taagagaaaa agagttagag cttgaggaaa ttcgtttatt tgatattgat aaaaaacgtc
     5701 aagataaagt agctgtagtt gtcaactgga tactaaaaga agatgttaaa acagatgtta
     5761 aactaactgt aactaattgt gaaaaagaag cgtatacaga tgctacattt atatttgcac
     5821 aaatgcgtgt tggtaaatat gaaatgcgtg agcaggatga aaaaattcca ttgaaatatg
     5881 gttgtgtagg tcaagaaact tgtggttgtg gagggatggc atacggactg cgtacaatac
     5941 aaccaatgat aaaggttatt gatgatgtag agaaatatgc taaaaaagat tattggatat
     6001 taaattactc taatcctgct gcaatcgttt ctgaagcttg tcgtaagtta agaccaaatg
     6061 caaggattat aaatatctgt gatatgccaa tagctattat agatatgata gcggggtcat
     6121 taaatatcaa tgacgttcat aatatacgct atgattattt tggtctaaat cattttggct
     6181 ggtttacttc aatagattat aaacatagag acttaatgga agagattaag gaatacataa
     6241 aagaaaataa aatattatta ccaaaatctt atatagaaaa cttaaataaa agtcgtagta
     6301 caggaaatcg ccatgctgta agtagctgga tacatgtttg ggaatctgtt tatacaatgt
     6361 tagaaagctt cccaaaatat ctgccaaaca cttatttaac atactatctt ttaagtaaag
     6421 aaacagtgga acattcaaac ataaatcgta ctcgtgcaaa tgaggttatg gaaagccgtg
     6481 aaaaagactt atttgaaggt gtgagacatt acttagaaac tggagaaatt tctgaaaaag
     6541 cattttatgc aggttcacat ggagattgga ttagtgattt ggcagtttca attaaaaatg
     6601 atacacgtag tcgtttttta gttataactg aaaatcgtgg agctatacca aacatgccat
     6661 atgatgcaat ggtagaaatt ccagcatata ttggtaaaga tggtccagaa gttattgctc
     6721 gaggtccaat acctctattt caacaaggat taatgatgca acaacttaac agtgaaaaat
     6781 tgatagtaga agcttatata gaaaatagtt atgaaaaagc tttacaagca ttcacattaa
     6841 ataaaactat tccaagtatg aatgttgcta aagaaatttt ggatgaaatg atagaagtta
     6901 ataaggaata ctggccagaa ttaagatagt aggataaaag aaagggtttt tatttaatca
     6961 ttagatatgt tttcagagtc ttttatcaaa atgtattcac aaacatatgg caatatatta
     7021 aaataaagag tgatattttt agaagaatgg ggtgatgcaa tgaacattat aaataaaatt
     7081 ttttggcaag aagataggat tggcatgatt acaaataatt tagaggcaga tacacatagc
     7141 cactgtatgt tacaactgtt cttagggata gaagacagca ttgaaataac agttaatgaa
     7201 aaattagtta aatgtaattg tatcatagta gataaaaata tctctcattc attttcagca
     7261 agaaaaaaag tttattactc tgctattatt gaacctacat ctatatatgc agaacagctt
     7321 acctcaaaaa tgaatgattt tggctactgg atatgtgaca atgatggatt agagaaatta
     7381 cgtcaacaag gaactttttt gatatctaac tctagtaaag aacaatattt aagatttatg
     7441 gaaatgctta ataactattt gaatatacct ataactctca aacattatga tgacagaatt
     7501 actgaattgt tcaatttatt acatacttgt aattgtgata atcatactat ttcaagtttt
     7561 gcagataaag tgtctctatc agcaagtaga ttatcacatc tgtttaaaga acaaataggg
     7621 atacctttaa aaagctatat cttatttcat caaatggagt gtgcttttag agaattactt
     7681 tctggaaaaa atgttaccga agcttctatg actgctggat tcgatactcc atcacacttt
     7741 gcagggacag ttaagcgaat gatgggaatg cctgtttctt tatctttgaa agatagcgag
     7801 tttttgaaag tatattaaat attctcgtta tataatgaag ttgtactaag aaaggggctt
     7861 tgttatgaat aaagaatatt tagaagaaac aaaaatgtta aattataatg aaccacaact
     7921 taagcttttg gtatcatcaa agaattggtt ggaattagat gattttcata aaataaaatc
     7981 tatttatgag tttgtacaga atgatatttt atttggatat aatgcttctg atatgttaag
     8041 cgcaacacag gtattaaatg atggtatggg acaatgcaat acaaaagcta ctcttttaat
     8101 ggcattatta cgtgcagtga atatcccttg taggcttcat gcttttgatg taacaaaaga
     8161 ttttcaacga ggagctacat ccaaattgat ttcactatta gcaccaaaat atattcttca
     8221 tacttgggta gaggtatttt atcaagatag gtggattgct ctggagggtg tcataactga
     8281 taaaaaatat ttagaagcaa ttcagaagaa attttttaat catggtggaa cgtttaaaaa
     8341 gtatgcaata gctacaaatg atttgaaaaa tacatctatt gattgggatg gtaaagatac
     8401 ttttatccaa aaagaagcta tcgtgtatga ttatggtatt tttccatcac cagacgtatt
     8461 tttttctact cattcacaac atatgtcaaa attaaaaaat ttcatatatg tacatcttat
     8521 cagaaaaata atgacaaaaa atgtatgtaa ggctagaaac aattatattg ataaaaatga
     8581 atgagtgttt aagaggtaac tatataggaa atatatagaa taattaaaac tgtactggtt
     8641 aaaatgaata aaaaggagtt atcacagagc aaacttaaat tgttcatagg ataactcctt
     8701 ttctgtatta acttctaata atttgatgtc tttttataaa acatatagat acaattaaac
     8761 cagtaaatgc aagagtagct gctattgaaa atgcaacatc tattccatga atgttagaca
     8821 gcatgtttga actcatatga gctttcttag tagcacttgt cattatagta ataagtatag
     8881 cagaacctat agctccagat atctgacgga gtgtgttatt aattgctgtg gcatgagata
     8941 taagttctct atctaatgtt ttaattcccc atgtagttaa tggcattaaa accattgaaa
     9001 taccaatcat acgaatacaa tacatcaatg acacatgaat taaagatgta tctctgccta
     9061 aaaaagcgaa ggataaagtt cctaaaaaca aacatcctgt tcctaatatt gatagagcat
     9121 gaggtccata tttatctaaa tgacgtcctg caattggatt gagtacaacc atcaatatag
     9181 caccaggtaa cattaatgaa cctgaagata atgcagaaaa tcctcttaca gattgaacgt
     9241 acagaggaat cattaatgta gcagacatca ttgaggcata tacaatcata attaatattg
     9301 tagaaataag aaatggttta tttttaaaaa ccctcaattc taaaaaaggt tctttagatt
     9361 ttaattgacg caatgtaaat aaaattaatg acataattcc tattaatatt ggtaaatatg
     9421 tggcaatatt agtccaccca taattacctt gattagtaaa tccaattaat aaaccaccaa
     9481 aacctagaga tgatagtact attgaaggta tatctaattt tagtttttga gtttccccaa
     9541 catttcttaa taaaataaat gatagtataa catctaatat agcaataggg gaaagaaaca
     9601 gaaataaact atgccaacca aatgaatcta ctaaccatcc tgataaagtt ggacctattg
     9661 ctggagcaaa tcctactgta ataccaacta aactcatagc tgcaccacgt ttttcctcag
     9721 ggcataaata gagtataata acttgtaaaa gtggcattag agaaccagaa cccattgcct
     9781 gcaacacacg agcaatcaac atagttgaaa aattattaga aaaaagtgca ataatacatc
     9841 ctatagaaaa gatagacatt gatgtaataa ataactttct agtactaaat cgatttatta
     9901 aataagctgt tgtgggtaca ataatacctg caataagtag ataaattgtt gttaaccact
     9961 gaccaacatc agcagtaatt ttaaaatctg acattatatt aggtaatgct gttgacaata
    10021 gtgtttgact gagagaactt ataaaagcac cagtcattac aattgctatt attaaatttc
    10081 cttttttatt gttactttgg gtttccataa tttataacgt ctcctttttt aattgatttt
    10141 taatgctgtt caataaaagt acttttggtc ttaaagtgtc ttctttttct aaatatgcaa
    10201 tcattgcatc cataattaaa gaatcatatt gttgattttt tccctcgacg tataattttt
    10261 ttattgcttc tagtaattta ggattttcaa ggagagaagt atcagttttg attagttctt
    10321 ctatatcttg tatcatttta aaaaatagcg atttattatg aagggaaaag taaacttcat
    10381 cttcttgttt atgtaaaaac attgattttt caattaaagg atttagatta tccatatttt
    10441 ctacaactaa atctagaatt tgtatagtaa atttggcaat aaagtataca tttatttctc
    10501 ttttttgtac atgaataatg tatataaact gatgaattag agcatccaat aagaaaacta
    10561 aatcaaatat aattttttct attttatcac catagttatc aaataagctt aatttgtatt
    10621 cattcaataa gttagctcgt gattttgttt gcaatttact tgtagcctta cgttgctctt
    10681 cagaaaaatt ttctcttata taggtattta tggtagttct agaaaaaata tttttccata
    10741 cagcaattat ctttctgttt aacttttctg atgctggaat gtcattattt tcatttatgg
    10801 aatgtataat ttctaaaaac ttttcatcat aataattgat tatttcgcag ataaaacttt
    10861 ccttagtttc aaaatgcttg taaaaagtag ctttagacat tttacactct tttacaacat
    10921 ccgatattga agtattttga aaaccctttt ggtcaaaaat tttttgtgca atagttataa
    10981 tgagcctttg tttttctgtc actttattat ctcctttcac gcaaaaacgt ttagtactat
    11041 agagtaccta caagttttaa taaatatatt atacatcatt tggaaaaaaa atcaatatat
    11101 agactgtaat atgaaatttt tgaaaaattt gttgttattt ttagtcgtat aaaaaagaaa
    11161 cttaagagtt tcttaagaat tgtttaaaga agttgcaata aattagtggt atgattatag
    11221 tatgaaagag aatgtcttga aatttttctg tatcaaattc caattatgga ggtgtagtat
    11281 atgaaaaaga aaatttgtgt agcaataatt tttgctctat ttatagtttt tgtagaaatg
    11341 tttattgata gctctagcga aggaagtaaa attatgacag ctgaattaag taaatacagg
    11401 aaaggcgtaa atgtattatc aataaacaat attatagtag cgaataaaaa atatagtttg
    11461 cccaaagatt attctcctca ggaaagcagt gaagcgagag atgcttttta taaaatgaat
    11521 aaagatgctc aaaagtcagg attaaattta aaagctttta gtacatatag aagttatgaa
    11581 tatcaagata gattatttaa gtcatatgta aaagaacatg gagaaaaaga agcaaataga
    11641 ttttcagcta aacctggaga gagtgagcat caaactggac ttgcttttga tattggagga
    11701 gatgaccagt cttgttgggc aaataaaaag ttcaacaata caaaagaagc taagtggttg
    11761 tatgaaaatg catataaata tggttttata cttagatatc cagaaggtaa agagaatata
    11821 acaggatata tgtatgaatc ttggcactat agatatgttg gaactgaaca tagcaaaaac
    11881 tttgcaatga ataatttgac tttagaagaa tatttacata taaattaaga gatggtttgt
    11941 taaaattagg ttaaaataaa aaataaccta gactattagc tgtgtaaagt gatataatgt
    12001 aaatacaatt tagataacta ctcgaagggg agtagcttac acgaaagtgg taattaatcg
    12061 tcaagacagt agaaatactc ggttaattag caagggattc cttgatagca agaccttcaa
    12121 aataagcatt aggtatgttt gttttggggt ctttttttat tcaaggaatt tttatttaaa
    12181 aaaatttaaa tttcaagtat acataagagc ccccaaacat aaaataaatt tattgaagag
    12241 gagggcaaca aatgtcttac aaaagtactt atcaagaagt aattaaaaat ttagactcaa
    12301 gtttatctgg tttgagtaaa gaaagagcag aagagttgtt agaaaaaaat ggagctaatg
    12361 aattaaaaga agcagataag gttcctactt ataagctttt cctagaaagt tttaaagacc
    12421 cattagtaat aattctattg atagctgctt tagtacaaat atttttaggt gaaacagtgg
    12481 agtctataat aatttttgca gttattatta taaactctgt tctgggtgtt gtacaaacaa
    12541 aaaaagcaga aagttcatta gaaagtttga aaaatttatc tgcaccaaac gcaaaggtaa
    12601 taagagacaa taaaaaaatg acaattccag caaaaaatct agtagttgga gatattgtat
    12661 tcttagaagc tggcgattac ataccagcag atggaaggct tatagaagca caatctctca
    12721 aggttgtaga agggatgtta actggagaat cagaaccagt tttaaagcat acagaaaaaa
    12781 taagtgaaga tgtaagttta ggtgaccaga aaaatatggt atttagtggt gctgtagttg
    12841 tttatggtag aggttctttt gtagtgactg gaacaggtat ggatactgaa atgggtaaaa
    12901 tagctgggct tttagaaagt gctgaaaata aacttacacc attgcaacaa aaaatagagg
    12961 attttagtaa aaaacttggt gtaggtattg taatacttgc tcttttaata tttataattc
    13021 aagtagcaag aaattacttt atggctggaa atggagaaat gacacaaatt attttagatt
    13081 cattcatgtt ctctgtagca gtagcagtag cagctatacc agaagctcta tcatcaatag
    13141 tcactatagt attggctgtt ggaacaaata gtatggcaaa aaaacaagcc ataataagaa
    13201 aattaccagc agtagaaact ttaggttcaa caagtgtaat atgtactgat aaaacaggta
    13261 ctcttacaca aaataaaatg acagtagttg attattatat gtatggaact aataatgatg
    13321 agttagataa agaaaaagta aactattctt atcatgctaa attattgact atggtttcta
    13381 cattgtgtaa tgactctcat ataactagtg atggtaaaga agttggtgac ccaacagaag
    13441 tagctttaat aaattattca agtaaaaatg atttagatta tgataaatta agaagtaagt
    13501 atatcagaat aaatgaaata ccatttgact cagacagaaa gcttatgtct actgtaaata
    13561 gtatatatgg agattatata atgtttacaa aaggtgctcc agatattgtg tttagtagat
    13621 gtaaatatgc tttgaaaaat ggttcaaaag tagatataac agatgagata atagaagaat
    13681 ataaacataa aaatgaagag ttttcaaata gagcacttag agtattagct tttgcaataa
    13741 aagatgtccc agaagaagat tttatacctt caattgatga cgaacatgac atgacattgg
    13801 ttggaataat ggcaatgata gacccaccaa gagaagaagt aatggatgca gtaaaagagg
    13861 caaagagtgc tggtataaaa actgttatga taactggtga ccataaaaca acagcagcag
    13921 caattgcaaa agagattggt ataatggaag aaggagactt ggctcttact ggaaaagagc
    13981 ttgatgcttt gagtgaagaa caactatatg aaaaactaga aaatataagt gtatatgcca
    14041 gagtctcgcc agaaaataaa attcgtatag taaaagcatg gcaacataag aataatataa
    14101 cagcaatgac tggtgatggt gttaatgatg cacctgcatt aaaacaagca gatataggaa
    14161 tcggtatggg aagtggtact gatgtagcaa aagatgcttc tgctatggta ttggttgatg
    14221 ataactttgc aagtatagta aatgctgttg aagttggtag aacagtatac agtaatataa
    14281 taaaatcaat tacttatcta tttgcaggaa acttaggagc tatagtatcc atagtatttg
    14341 cagtgtttgc aggttggtca aatccattta cagctttaca acttttgttt ataaacttag
    14401 taaatgactc tttaccagca attgcattag ggtttgaaaa gtcagaaaaa aatataatga
    14461 ataaacctcc tagacacccg gatgaaagta tactagcagg aggaacattg aaggcagttg
    14521 ctataagagg ttgtataata ggtgtagtta caataattgc acaatatata ggattacaag
    14581 tatctccaga acttggagta gcaatggcat tttcaacatt gatattagct agaataatgc
    14641 aaacattacc tgcacgttct aataatcaaa cagtaataaa attaggtttt ttcagcaata
    14701 aatacgttat aggagcagtt ttagtctgtc ttgggcttta ctctttaaca ctaataccag
    14761 tgctaagagg aatattctct ataccaacaa cgtttggatt gtaccagttg gggatttgcc
    14821 tagggttagc attaatttca tcaatattaa tggaacttaa caaattaata aatagaagtg
    14881 aagtaaaata atcaaaaaat taaagggcat attgatttta acaatatgcc ttttataaat
    14941 agtctaattt attctatatt atcgattatt tggaatgctt ttataacttc aggtaattct
    15001 ttttcttcag gcattctaaa tcttatgaaa tttttatcaa gtccagtaaa atcacttcca
    15061 gatataactc ttatttttaa tttagcaaac tcttgttgta aatctatgtc cttgttttta
    15121 tgttcaactg tcataattga tacagtatca ctagtttcag ctatattaag gtttttccat
    15181 ggaattaata attgattttt tatatctttt gttttttctt ttaattcttc tataaattga
    15241 acatcatcta ataaatttgc tgcaatacta cgagatattt cagacacttc gtaaggagta
    15301 gaaatctttt taatagggct aacaagttgt tctggaagaa ctgcatatcc tgctcttagt
    15361 cctgctaaac cgaatccttt tgaaaatgtt tttaaagcaa ttacattatc ataattattt
    15421 agaagcttga cagctgaatt ttcttttggc atgtattcac cataagcttc atctaccata
    15481 actgctatat catatttagc tgcttccttt actatatttt caattgatga taaatgtata
    15541 atttgtcctg taggattgtt tggattgtct atgtaaatta ctttatattc tggatttatt
    15601 ttttcaataa attctttttc attaaacttg aaattatcct ctttctttaa aagaacataa
    15661 tcataagttg caccatgcat ttttatatct gtctcatatt ctgagaactg aggtgaatat
    15721 cctaaaactt tatctccctt ttcaataaat agtctattta aaaggtaaat aacatgtata
    15781 gaaccatctg ccaaacaaat tctgtcagta tctaatgcta taaaatcttt ccaataatcg
    15841 actatattat cttttaaagc aattgaatga ggatatcctc ttatcatatc aaattttaaa
    15901 gcattaaaag cttctacagc tttgtttgag taagacacgg tatttatacc ttcaccacag
    15961 tctatctcga atacatcttc tgaatgtcca gattctattg cataactttt tttcaactgc
    16021 atttcaatag ctttgttaat ttttagtttc atactttatc actccttatt tagtcaataa
    16081 taaatgttat aaaagttgct agatttaaaa tattatgaaa atatataata gtaaaaaatg
    16141 aatataaata ttataatagc tcactttatt taatatgatt atatatcata tattgtaaaa
    16201 tttctagcat tataagacta taaattgaaa atattcagaa aaatactaca agaaacgatt
    16261 tattttgctc ttaaaataag ttaaatgaat gttattaatt ttgtaaattg aaatagttta
    16321 agtataaagt tatgatataa tctaataagg gtaattcttt agattatatt aaggaaatat
    16381 aggtatacaa taaaaagtta tggagttgga ttatgggata taaattaatt gtaacagata
    16441 tggatggaac tttattaggc aataatcata aagttacaga tgaaaataaa actgcactac
    16501 aaaaagttat aaaaagcggt attaatgtaa ctttagcaac aggaagagcc ttcgattcag
    16561 ctaaatgcaa tgtagatttt cttaaagagg acatgccaat aatagcttgt aatggttcat
    16621 taataagaga gcaaaatgga aatataatat attcaaataa gattgataca agaacatgtt
    16681 taaacatttt agatgtatta gataaatacg atatttacta ccaatgtaat agtatagatt
    16741 ctatgctttc gaaaaaaata gaaggacgtg aagatagatt aagtgtattt ttaggctctg
    16801 aaacagaagt aattgtaaaa gatgatttga gagaagaaat ctttaaaaaa gatatactaa
    16861 aatttgtaat catagaagaa aaaaatccat ctattttaga tgaaataaga aaagaattga
    16921 gaaaagttca aggaataaag ataacttctt catggccaaa caatattgaa gtcatgaatg
    16981 aaggtgttga taaaggtaat gcagttaaaa ttttagctga aaaaatgaat atagacagag
    17041 aagatataat tgcatttgga gacaattaca atgacataga aatgataaag tttgctggtc
    17101 ttggggtagc tatgggaaat gcagaagaat tgattaaaca agaagctgat tatgttacag
    17161 atacaaatca agacagtgga gttgcaaagg caatttataa attcctagag ttaaaagaat
    17221 cacttagctc ttaaaacagt atataatagg aaaaaatagg ttgactattt tgtagatagt
    17281 aattataata caaatagata aaacataaaa atttagattc agtgaaaaag agagtagata
    17341 tagagaaaat ctcagcgaat tgggggatgg tgtgagccta atgataacac tttatattga
    17401 aaagaacttt ggagaatact acttgaaatt cagtatggta gtaggtaatc tcgccttaag
    17461 agaatagagt gggtaaacat tgtttaccaa ctagagtggt aacacggaat atttcgtctc
    17521 ttggtctttt tgaccaagag attttttagt ttcattgagt tacaagactt ataattaaaa
    17581 tacaaaaaat taaaatatga ggtgaaagtt atgaaattat ggggcggacg ctttagaaaa
    17641 gcggaaaatc aacttatgga agaatttaat aaatcttttg gctatgattg tgtactgtac
    17701 aaaaaagata tcgaaggaag tgtagcacat gttcatatgc aagtaaaatg tggactttta
    17761 acagaagaag aaggaaagtc tataacagaa ggtttaaaag ggatacttga agatgtagaa
    17821 aatggaaagt tagtattgga tggagagtat gaagatatac atagttttac tgagataaat
    17881 ttaattcaaa gaattggaga tgttggcaag aagcttcata cagcacgtag tagaaatgac
    17941 caagttgcag ttgatatgag attgtatgct aaagaaaaag caaatgattt ggtgggttta
    18001 atatctgaat ttaaagctac tataaaagat gttgctgaca aaaacccagt gatgatgcca
    18061 ggctatactc atcttcaaag agctcaagta gtgacattta agcatcactt aatggcatat
    18121 tatagtatgt ttgatagaga tgagaaaaga ataaaaaatg ctatagaaat attagatgaa
    18181 tcacctttag gctgtggagc tttagcagga actacgcatg atatagatag aagtataact
    18241 tgtgaacaat taggatttaa aaaagtagta gataatttta tggatggagt aagtgataga
    18301 gattatttac tagagctaat gagtgatttt tcaattataa tgatgcactt aagtagatta
    18361 agtgaagagt tgatactttg gagttctcaa gaatttggat ttgttgagat agatgattta
    18421 tatacaactg gaagtagtat aatgcctcag aagaaaaatc cagatggtgc agagcttata
    18481 agaggtaaga ctggcagagt atatggaaac ttatttggtc tttttacagt aatgaaagga
    18541 ataccattag catataataa agacatgcaa gaagataaag aaggtttttt cgatagtgta
    18601 catactcttg aaatgtgtat acaaataatg gatagaatga tagccacact aaaggtaaat
    18661 gaggataaaa tgaaacaagc agtaaaaaat ggttttttaa atgcaacaga agttgcggat
    18721 tatttggtta aaaataatgt tgcttttaga gatgcacatg gtatagtagg aagtatcgtt
    18781 atatattgtg aagataataa aaaagcaata gaagatttaa cattagaaga attacataag
    18841 ttttcagatg cttttaagga agatatttat gattttatcg actatgagag tatattaaat
    18901 aagggaataa aaaagaattt aaaataatgt atttattttt aaaagctgta aatttgaatg
    18961 ttatcattta aatttacagc tttttattgt gtaagatttt attatataaa agtaagaaac
    19021 ttaaaagtag tagtatttaa aataaataca aataaaaaat tgttattaaa atgataatta
    19081 atatcaataa gtattgacaa aattatttct aaatactatt atatataata taaataataa
    19141 tgaaaatcaa tatcaaataa atgggaggaa atctaatgaa cttattagtg attggtggtc
    19201 atgaaagaat ggaaaaagat tatatggtta tggccaagaa aaaaggttat aagacaaagg
    19261 tatatactac catgtcatct aaattaaata attctatagg aagaccagat gcagttgtca
    19321 tacttacatc aactgtttca cataagatgt ctagaacggt tgagtctcaa gctaaaaaac
    19381 aagatatatt aatcgtaagg cataaaaata gtagtaaggt agcatttaat gaatgtctag
    19441 atatggttga tgaatgtctg ggaaattgtt caaaatgtaa gcttaaagac aaacaaaaac
    19501 aaaaaaatat ataggtataa aaaatacata aacataaaat taaaagtact gagataatag
    19561 ttataattat tatctcagta cttttagatt tataaggata agtatattat aaatttttta
    19621 ttataatttc caactacttg ttactttttc atattttttt tacttctagc tttttttctt
    19681 tttttcttct ttatatttga agctattata aataaaacta aaagcactag aatacctgca
    19741 ataatcttaa caaaagtcat taaaatatta tttccagtaa aaaatggaag actgctatca
    19801 agattatttt ttgcaattaa gtctatactg ttttctagtt taccattatt atatacattt
    19861 aaagtaccaa ccttagcccc tttttttata ggcaaatcaa ttttatttaa ctctgttttg
    19921 gtatcataat tgccttgaga ttcatctttt tctaagaata tcctataact attttttggt
    19981 tcataaatca attcatgttg ttttgtaaac aatacttttt tagtatctgt gtatttttct
    20041 ttatcaacaa tagtagcaca cttaaagtta tcaaatccat aatcaatcag aatacgtgag
    20101 tctaaatata aatcagcatt agttgaatta aatacagcaa cgataactct tctgccatct
    20161 tttacagcac tcgataaaag acatttacca gcagcatcag tatatccagt ttttatacca
    20221 tcaactatat catattttat atttataggt tgacctttgt atgtaatctt atcatgtgat
    20281 gtcaaaaact tattagtgtt tacaaagtat ctctcataag gatatgcttt tgtagcttca
    20341 aatttaagtg acttagtttt tacaatttgt ctaaaagtat cattattcat agcttctcta
    20401 gctatgagag ccatatcatg agctgttgtg tagtgatttg ggtctggtaa tccatgagga
    20461 ttattaaaat gagtattagt agctccaatt ttttttgcct cagagttcat aaggtcaata
    20521 aatttttgta cattgccacc accaacatat ctagctaata caaaagcagc atcattagca
    20581 gaatgaacca aaagagcatc tagtaactgc tttacagtaa aagattcccc attttttaga
    20641 tacatactag agccatctat ttgaggtaaa tctttaattt ctattacttg atttaaatct
    20701 ttaacctcct ttagaactaa acaagctgtc catactttag ttgttgaagc tggataaagc
    20761 ttagaatttc catccttatt atatagtatt ttgccagact catagtccat taaaactgca
    20821 tgtttagcaa ctatagctgg ttcattatct gcaaaagaga tattagagct tcctaaaaat
    20881 gaagtaaata tcaataaaca gattaataaa agtgataaat ttcttttcat tgtgagcctc
    20941 caaattttaa attcatcttt tagtatagca tatatttgtc aataattaaa agaaaggagt
    21001 gattaatata tgaaaaaaaa agtaaaattt atttcgtttt ttgttttatt tattttaata
    21061 atatcatcaa taatcgttta taaatcgctt attttcaaag atgatattta tgttgtaagt
    21121 aaaaaaaatt tacctaatga aaaaacacat gttgtagaga atgaaattaa aggtgaagat
    21181 aataatcaca ataaagtaac taaagacata gataaaaatt ttcaaaataa taaaataact
    21241 atatacataa gtggagcagt aaatagacct ggaattgtaa ctatagagtc agacaagaga
    21301 ctttatgatg ctgtagaatt actaggagga acgacaaaag aagcagattt aaatggagtc
    21361 aatctatcag taagattaga agatgaacaa cattacataa tacccaaaat aggtgaagca
    21421 acatctgtta caagtaatga tgattccaat aaaccaaatc agaggaatga gtcaagaggt
    21481 gagcctaaaa ataaatccaa taaaaatata tctaacgaat caaaagtaaa tataaatgta
    21541 gcgactatag aagagttgga ttctctacct ggggttggag aagctacagc caataaaatt
    21601 ttacaacaca gagaagaaaa tggacagttc agttcaattg aggaaataaa aaatgtaaat
    21661 ggtattggag ataaaaagta tgaaaatata aaagatttaa tttgtgtaga ctaaaatata
    21721 atacaaaact tacatataga tatgttatta taaatatgta tgtatatgtg tgtacatgtg
    21781 gaaatttagt aaaggaggca cttttatgaa aaaagaacaa aaaaaactta cagagatgac
    21841 aacagcaggt ggttgagccg ctaaaatagg gccagaggtt ctggcatcag ttttatctca
    21901 attgcctaaa aatgataata tagaaaattt attagtagga ctagatacag cagatgatgc
    21961 tgcagtttat aaattaaatg atgatatggc acttatccaa actttagact tctttacacc
    22021 aatggtagat gacccatacg tatttggtca aattgctgca tcaaattcac tatcagatgt
    22081 atatgctatg ggaggcaaac ctttggttgc tatgaatatt gtttgttttc catcatgcca
    22141 tgatatggat gtacttgcag aaatattaaa aggtgggttt gataaagtga aagaaagtgg
    22201 agcacttttg gttggagggc atactgtaga tgacaaagag cctaaatatg gtctttcagt
    22261 ttctgggatt gtaagtccaa ataaagtttt atcaaatgct actgcaaaac ctggtgataa
    22321 gttaattata acaaaaccaa ttggagtggg tgtattaaat acagccatga aagaaggtat
    22381 ggtagaacaa catatagcag ataaagtaat agaaataatg atacatttaa ataaatatgc
    22441 agcaatgagt tttgagaaat ttgatgtaaa ttcggttaca gatataactg gttttggtct
    22501 acttggtcat actttagaaa tggccaaagc ttctgaagta agtattgaaa ttgaatcaaa
    22561 acatgtacca attattgaag gtgcaataga aatggcacaa atgggaatta tacctgctgg
    22621 tatgtataaa aatatgcatt atgtatctaa agatgtagaa gttgtaggaa atatagaagt
    22681 tgcagttcaa gatattttat acgacccaca aacatcagga gggttgttaa tttcagtaaa
    22741 agaagaactt gcagaggaac ttgtaaaaga tatgaaatta aatggagcaa tagaagctaa
    22801 aattataggt tctgtagttc caaaagggga aaaatatatt acagttttat aaaatattat
    22861 agagaaagag tgattgtttt gagcaaaaga gaattgtttg caatgttgcc ttcagttgat
    22921 gaagtattaa gtgataatag aattgtagaa ataataaatg aatatcctag aagtttagtt
    22981 ttagaatctg tgagagaagt aatagattta aaaagacaat ttatattaag attaaaagaa
    23041 gatgcatcaa actctgtaac aatagagttt ggtgaaataa tagaatctgc aatagagaga
    23101 gttaagttaa attactcatt atctttaaaa aaagttataa atgcaactgg tacagttatt
    23161 catacaaatt taggaaggtc tttacttagt gaagatataa aagatgaatt atggtgtgct
    23221 gcttcaaggt attcaaactt agaatacgat ttggataatg gagaaagagg ttcaagatac
    23281 tctcatttaa ctagtacaat aaaaagactt actggagcag aagatgtact agttgtaaat
    23341 aataatgcag cggcagtact tcttgtactt agcacaatgg ctaaaggagg agaagcaatt
    23401 gtatctcgtg gagaattagt tgaagtaggt ggttcattta ggattccaag tataatggct
    23461 cttagtggtg cagaattagt tgaagttggt tcaactaata aaactcattt gaaagattac
    23521 aaggaggcca ttacagaaga tacaaatgta ttgatgaagg ttcatacaag taattataga
    23581 ataatgggat tcacagagag tgtttctata gaagaattgg ttaatttagg taaaaaatat
    23641 aaactacctg taatagaaga cttaggaagt ggagttttta tagatttatc aaaatatggt
    23701 ttatcttatg aaccaactgt attggattct attcgacaag gtgcagatgt agtaactttt
    23761 agtggagata agatgcttgg aggtccgcaa gcaggtatta tagttgggaa aaaagagtat
    23821 atagaaaaaa tgaagaaaaa tcaacttact agagcactta gagttgataa gcttacaata
    23881 tgtgctcttg aagcaacatt gagaatgtat ttagatgaga caaaagctat agaaaatata
    23941 cctactttaa aaatgttgac atataaaatt gaagaattag aagtaaaagc aaataaacta
    24001 tttgaaaaaa taactgcttt aaacttaaat gcaaacataa atatagaaga tggattttca
    24061 caggtgggag gagggtctat gcctcttgaa actataagta caaaggtaat atcaataact
    24121 cctgaacata tgaatgtttc atctttagaa aaaaaactaa gacttagtga agcacatata
    24181 atagccagag tgtatgataa taaatatgta ctagatgtaa gaactatatt tgatgatgaa
    24241 tttgatgtaa tagttgagga attgagaaaa gcatttaatt aaataaattt gagttaataa
    24301 atattaaatt tagaagtata agtatgaagt tttgattaaa aaatagctac acacacttgt
    24361 gactttagtc atagcaggtt tagagggggc aaaaaatgaa aaatgtagta attggaacag
    24421 caggtcatat tgaccacgga aaaactactc ttataaaagc attgactgga agagagactg
    24481 atacgttaga tgaagaaaaa aagagaggta tttcaataaa cttaggattt acttattttg
    24541 atttaccaaa caatagaaga gctggaattg ttgatgtccc aggacacgaa aaatttataa
    24601 aaaacatgtt agctggagca tcaggaattg atatagtttt acttgttgta gcagcagatg
    24661 aaggggttat gccacagaca gttgagcatt tagatattct aagcttttta aatatcaaaa
    24721 atggaatagt ggttctaact aagtctgata ctgtagatga tgaatttaga gagctagtaa
    24781 aagaagatat ttgtgaaaaa ataaaaggaa cttttcttga agatgctgaa ataattgaag
    24841 ttgattctat atctaaaaga ggtatagaca ctcttattga aaaaatagat aaaatgagtg
    24901 atgatataga agataaaaat gaaaactctc cagcaagact taatatagac agagtatttt
    24961 caataaaagg gtttggtact gtaataacag gcactttaat agaaggaaag ataagtatag
    25021 aagatgattt ggttatatat ccacaggtat taaaaacaaa aataagaagt atacaagttc
    25081 atggagaaaa taaagataca gcttatgcag gtcaaagaac agcaatcaat atatcaaatg
    25141 taaaagtgga tgatataaaa agaggagatg ttttagctgc accaaactca ttggaggaat
    25201 caatgatgtt agatgtaaaa ttatcattgg taaatcattt agataaagga ttaaagcact
    25261 gggatagatt aagattgtat catggaacta gagagatact ttgtagagca gttccactag
    25321 ataaagaatt aattgaaagt ggagaaagtg gctatgttca gttgagactt gaagaaagca
    25381 tagtatctaa gaaaggtgat acgtttgtag tgagacgtta ttctccaatg gaaactatag
    25441 gtggaggtgt aataattgac ccatctccta aaaaacataa gaaatttgat gaaaaagtta
    25501 tagaagcatt aaaaataaaa gaaaaaggcg aactaaaaga tataatagaa gagtacttaa
    25561 aaaggaattt aaaaaattat ccaaatataa aagaaataat gagctatagt ggtgctcatg
    25621 aagaagatgt aaaaagagcg cttgaaacac ttatatcaga agataaagta tttattatag
    25681 gaaatatgta tatgcatata aatcaataca ataaattaaa agaaaataca ataaagcttt
    25741 taagtgagta ccataagaag tataggctta gaaaagggat actaaaagaa gaagtaaggt
    25801 ctaagataga gagtaatttt aagactaggg agatggatat tttattagaa aaattgtcta
    25861 cagaaaatgc tataaaaata gaaaataata tagtatctct attagatttt gaggttattt
    25921 taaatgataa gcaaaaagaa atagcaaaaa aaatagaaaa aagattaaaa tcatgtggag
    25981 tttcttctat actgacaata gatgaagttt ctgaaggaaa tcataactat gctgaagtat
    26041 tggagtcaat gataggtaat aaagtagaga aattagatga tttgtatata atggacaaag
    26101 atatttatga aaatgcaaag aacattttga taaattatat aaaagaaaat aaagaaataa
    26161 cattaggaga atacagagat ttgattgatt ctagcagaaa gaattgcatg attatattgg
    26221 aaaacttcga tagaaacaaa ataactaaaa gagtagaaaa caaaagaatt ttgttttagc
    26281 agaaaatgtc tgtttttgct ttaaggtata aagaaggaat tataatgtcg agtatcgtat
    26341 aattaattag tataaaatat taattaagag gaagtgtaaa gtattgaaga atataatacc
    26401 tgatgtaaaa ccagatataa aagaaagaga agacatgagc cttttattta taataatggg
    26461 ctcagtactt ttattattta ttataaaaga tatagagaaa tatgaaactt tattacatgc
    26521 catatatacg atatttttag tagctacagg agtaattata tttaatacta caaaatttaa
    26581 agtagattca ttttctacat ttttaggatt aatttttata gctactggag tattggagtg
    26641 tatatattta tttaattcct tggggattaa aactaagtct ataatggaga ttaacatcac
    26701 aatatcagca ataacag
//
LOCUS       DAEPKC010000050        26478 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.050, whole genome shotgun sequence.
ACCESSION   DAEPKC010000050 DAEPKC010000000
VERSION     DAEPKC010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 26478)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26478)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26478
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.050"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(<1..245)
                     /locus_tag="KR294_002154"
     CDS             complement(<1..245)
                     /locus_tag="KR294_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBH0240232.1"
                     /translation="MNREKLVAFIRYLSLFILVVSYLKNVENTLYPVITMIILFLIII
                     NNQVRFFSLSNENKFILISYFLELILIFILCNYTKTF"
     gene            429..773
                     /locus_tag="KR294_002155"
     CDS             429..773
                     /locus_tag="KR294_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YraN family protein"
                     /protein_id="HBH0240233.1"
                     /translation="MNNKEKGDFGEKVAVNYLLSKGAKILEKNYRLKIGEIDIIAKME
                     DEIIFVEVKSRSNIKFGYPCESVSFKKRKKIIGVANYYIIKNNLNNTPVRFDVIEVYL
                     LEKRINHIMNAF"
     gene            804..2405
                     /locus_tag="KR294_002156"
     CDS             804..2405
                     /locus_tag="KR294_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YifB family Mg chelatase-like AAA ATPase"
                     /protein_id="HBH0240234.1"
                     /translation="MLSIINSSNLVGIDSFLVKVEVDVSNGIPSFNIVGLPGKEIKEA
                     RERVKSAILNSGYKFPSTRIVVNLSPADIKKEGAFLDLSISIGLLRELIKKDENYIRE
                     SMFIGELSLDGKIRKVRGILPIIMGAKTQNIKRIFIPIENIKESLFVDEIDIIPIKSL
                     KECVDFLNEEIKVDKVRIMSFLDDKSRKENEELEKDNSYIDCKYTKINNEESKYDEDF
                     KDVKGNYFVKRSAEIAAAGNHNMFMIGPPGSGKTMIAKRVRTILPDISVEEMIEVSKV
                     YSILGMINETKGIIDKRPFRAPHHTTTKQSLIGGGMDARPGEIALAHRGILFLDEIAE
                     FDRKILETLRQPIEDGYVNISRVKYSAKYPCRVLLVAAMNPCPCGYYMSETECRCRSN
                     EIDRYINKISGPLLDRFDIFVEVNSIKYSDFNSLKQEESSQKIKRRVENARKIQINRF
                     KKDNIKNNSEIKAYNLFKYCKLEKEASKTAEMIFNKYNLSSRSYTKLLKMARTIADLE
                     ERDLINSQCIIEAFSFRKAYYSYFK"
     gene            2424..3524
                     /gene="dprA"
                     /locus_tag="KR294_002157"
     CDS             2424..3524
                     /gene="dprA"
                     /locus_tag="KR294_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HBH0240235.1"
                     /translation="MEKRDTYLWLKSIGGITTKTIEIIENEIVNIEDIFDFSEKEIYN
                     LKNISLNIRKNIVKYRGHAYLENIKELLYKKAIKYICKYDKEYPENLKNIYNAPKLLF
                     YKGDIGLVNNNFNIAIVGSRKPTAYGINCAKTISCQLSQYGVNIVSGLAIGIDAYSHI
                     GCMSGKSKTIAVLGSGVDNPLPKQNLHLSNKILENGGLLLSEYNINSTVAPYHFSNRN
                     RIISGLSDGVVVVEAAIKSGALITVDFALEHGKNVFAIPGNINSQMSRGCHKIIKEGA
                     KLIENIDDILNEYNIFNIIDKKINQKYDNISLNAKSKQIIEAIKREGNLHIDSICDYT
                     GIEIKYVNSIINELVLNELVVEMNNKTYSLNV"
     gene            3557..5644
                     /gene="topA"
                     /locus_tag="KR294_002158"
     CDS             3557..5644
                     /gene="topA"
                     /locus_tag="KR294_002158"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HBH0240236.1"
                     /translation="MAKTLVIVESPAKAKTIEKFLGKSHYTVKASVGHVRDLPKSKLG
                     VDIENNFEPQYINIRGKGDVIKELKKEAKKSKQVYLATDPDREGEAISWHLAHILNLD
                     ESEDCRIEFNEITKDAIKKAIKHPRNIDINLVDAQQARRVLDRLLGYQISPILWQKVR
                     KGLSAGRVQSVTTKLICDREKEIKAFIPKEYWTIDVEAKTVKDKDITLKFYGKNDEKI
                     ELENEEAVNEILKEMEGKDLKVEKIESKSRRKSAPKPFTTSMLQQEGANKLFFTTKKT
                     MMIAQELYEGIDIEGEGTVGLISYIRTDSKRISDEAKEKAKGYIVNNLGENYYKNTGD
                     KKEKKDTKKVQDAHEAIRPTSVDRTPESIKASLSKDQYKLYNLIWRRFVASQMEDSVF
                     DILNVECKIGDIVFKATGSKMKFDGYTKVYNFSEREDKILPSIEKGDILNIENILPDQ
                     HFTQPPARYTEASLVKTLEELGIGRPSTYAPTIATILNREYVEKQGTSLCPTELGIIV
                     TDILENNFHKFIDVDFTADMESKLDVIEEGNTDWKKIVSESYAPLKEAIEEALENIEK
                     VNMDEETDEICENCGSNMVIKYGRFGKFMACKNYPDCKTTRPIMNKIGVKCPKCEEGD
                     IILRKSKRGKAFYGCSNYPNCDFVAWNKPTGEFCEKCGSYMVEKVTKSETKTVCSNKE
                     CNKETKEHNDGKE"
     gene            5809..6594
                     /gene="codY"
                     /locus_tag="KR294_002159"
     CDS             5809..6594
                     /gene="codY"
                     /locus_tag="KR294_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HBH0240237.1"
                     /translation="MASEVLQKTRKINKTLQTSGGSSVSFDLLAGALGDVLSSNVYVV
                     SAKGKVLGLHLNDVQDSSVIEDEYTKQKKFSDEYTQNVLKIDETLENLNGEKILEIFP
                     EEHGRLQKYTTVVPILGSGQRLGTLVLSRYSNSFNDDDLVIAEYSATVVGLEILRAIG
                     EELEEEMRKKAVVQMAIGTLSYSELEAVEHIFAELDGKEGLLVASKIADRVGITRSVI
                     VNALRKFESAGVIESRSLGMKGTHIRILNDKLTDELKKLKNNQ"
     gene            6701..7966
                     /locus_tag="KR294_002160"
     CDS             6701..7966
                     /locus_tag="KR294_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HBH0240238.1"
                     /translation="MPLADKIRPKTMNDVIGQSHIIGNGKILSKILQSNFLPNMIFFG
                     PPGVGKTTVAEIIAERSNKSFYKINATNSSLEDIKKVISELGSINNVNGVLLYIDEIQ
                     SFNKKQQQSILEFMENGSITLIASTTENPYHYVYKALLSRSTVFEFKPLEKLDVEKGL
                     KRAVEVLNEDSYMDIECNNNAIEDIAILSDGDMRRALNILEVVVYSTKPNKDNITYID
                     SDVIRASTFNKIINYDKNGDSHYDILSAFQKSIRGSDPQASIHYLARLIKGGDLISIC
                     RRLLVIASEDIGLAYPNAIVIVKACVDSAMQLGFPEAKIPLAEATILLATSPKSNSAC
                     IAIMKAMDELDKEFVKDIPNSIKDSHYSGSKEIGRGCGYKYPHNFKNHYVKQQYLPDS
                     IKDSIYYIPQENKTEKNIKKYLEYLNSDF"
     gene            7997..8767
                     /locus_tag="KR294_002161"
     CDS             7997..8767
                     /locus_tag="KR294_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH0240239.1"
                     /translation="MIIKLNSTYHSRVMKYLKKEPEYNLFIIGDIERYGYGNNFLNIW
                     ADVGEHGEIKAILLKYFEFMIFYSDGEYDVEGFYNLLRNTNYEEISGKICAVDALAKR
                     LGLNNLKVVDFCKLQTKKFLIDNNCNAKVKRIRLGNLKKTVKLYDLIDEFHSTTLENL
                     KNGLRTGRGYCIEINKQVVSMAKSTSENRTHAMIIGVGTHPKYRAKGLATKCLIKLCS
                     ELLRENKIPCLFYDNEEAGKIYKKLGFENIGKWGIYSK"
     gene            8876..9322
                     /locus_tag="KR294_002162"
     CDS             8876..9322
                     /locus_tag="KR294_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HBH0240240.1"
                     /translation="MKLSTKGRYGLKAMFELALNQDNGPVSLKFIAKKQKISDQYLEQ
                     IFSSLKKSGLVKSVRGAQGGYLLSKNAEDITVGDILVVLEGPVALSDCVLDEDVCENS
                     NMCVTKIVWEKMKKGIEDVIDSITLKDMINDYNKNKLENDITNIKK"
     gene            9340..10533
                     /gene="nifS"
                     /locus_tag="KR294_002163"
     CDS             9340..10533
                     /gene="nifS"
                     /locus_tag="KR294_002163"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase NifS"
                     /protein_id="HBH0240241.1"
                     /translation="MEKRRLYMDYSATTPIKKEVLDAMMPYLTDYFGNASSFHTFGRE
                     AKDALDKAREQVAALINAEPSEIYFTAGGSESDNWTLEGVAYANKNKGNHIITSKIEH
                     HAILHTCEYLAKHHGFEITYLDVDSEGKVDLKQLEDSIKDTTILISIMFANNEIGTIQ
                     PIKEISEIAKKHKILFHTDAVQATGNIPVDVKELGIDLMSMSSHKIYGPKGVGALYIR
                     KGVRLHNFVHGGAQEKSKRAGTENIPAIVGYGKAAELAKENMQNHVETLTRLRNKLID
                     GVLERIPYTRVNGSLDNRLPGNANFAFQFIEGEGILLLLDMLGIAGSSGSACTSGSLD
                     PSHVLLAIGLPHEIAHGSLRLTVGDFTTDDDIDYILENLPKVIERLRSMSPLYDDAKK
                     QGLVK"
     gene            10587..11027
                     /gene="nifU"
                     /locus_tag="KR294_002164"
     CDS             10587..11027
                     /gene="nifU"
                     /locus_tag="KR294_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly scaffold protein NifU"
                     /protein_id="HBH0240242.1"
                     /translation="MQYSDKVMEHFMNPRNMGEIDNASGVGEVGNPTCGDIMKIFLDI
                     DGDVIKDVKFKTFGCGSAIASSSMATEMIKGKTIKDALELTNKAVAEALDGLPPVKMH
                     CSVLAEQAVKAALIDYAQKNNIHIPELDGYVIDDAHDHDVEEEE"
     gene            11316..12395
                     /gene="mnmA"
                     /locus_tag="KR294_002165"
     CDS             11316..12395
                     /gene="mnmA"
                     /locus_tag="KR294_002165"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HBH0240243.1"
                     /translation="MNKKVMIGMSGGVDSSVAAYLLKQQGYDVIGVTMKLWQDDDVVE
                     IEGGCCSLSAVEDARRVANKIGIPFYVLNFREVFKEKVIDYFIDEYLEGKTPNPCIAC
                     NKHIKFDDFYKKARQIGCDYVATGHYAKIEKDESTGRYLLKKSVTDKKDQTYALYNLT
                     QEQLEHTLLPIGDYEKDRVREIAKEMGMAVHNKPDSQEICFVKDNDYANYVKKHSKKR
                     IEEGFFVDTKGNILGKHKGILYYTIGQRKGLGITFGKPMFVIDINPINNTIVLGDNED
                     LFKKELIAKDVNFISIDTLEEPLRVQAKIRYSAKPSPATIHRVGEDTIKIVFDEAQRA
                     ITKGQSVVMYDGDIVVGGGIIEKSL"
     misc_binding    12538..12776
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            12844..15483
                     /gene="alaS"
                     /locus_tag="KR294_002166"
     CDS             12844..15483
                     /gene="alaS"
                     /locus_tag="KR294_002166"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HBH0240244.1"
                     /translation="MEKMGLNEIRSKFLEFFESKGHYVANSYSLVPNNDKSLLLINSG
                     MAPLKNYFSGVEVPPSVRMCTSQKCIRTGDIENVGITARHATFFEMMGNFSFGDYFKR
                     ESIKWGWEFVTEWLNIPEDKIWVTVYEEDDDSYDIWAKEMNFPEERMVRLGKDDNFWE
                     IGTGPCGPCSEIYFDRGEEYGCDNPDCKPGCDCDRYLEFWNHVFTQFDRDEEGNYSLL
                     ENKNIDTGMGLERMGCIMQGVDTIFEVDTIKSILEAVEKLTGVKYGENPKNDISIRII
                     TDHIRAVTFLVSDGVLPSNEGRGYVLRRLLRRAARHGKLLGVKELFLQKLIDEVIKVN
                     DKAYPVLVEKESYIKKVVGIEEEKFNETIDQGTEILNSYIEVLKNEGKTVLSGQEAFK
                     LYDTYGFPIDLTKEILEEEHLSVDEEAFNEEMEKQKERARNARGNMDGESWKEDPLSK
                     LESTVDSTFNGYSEIYGEGTIEAIVKDDELVQSAEEGDKVSIVLDNTTFYPEGGGQVG
                     DCGLITNENLVLEVLNTKKGANNSIKHIGIIKSGRISNGDKVKTLVDRETRMSAARNH
                     SATHLLHKALREVLGEHVNQAGSLVTPERLRFDITHFEAISNEELKVIEEKVNNVILS
                     SLDIKCDIMNIKEAKEKGATALFGEKYGDEVRVVSMGDYSTELCGGTHLTNTSQVGMF
                     KILSEGGVAAGVRRIEAITGKAVYEYLKERDGIISEVCVNLKSKEDNLIQRISSLLEE
                     NKNLSKELHDMKAKMSLQSVDSIFDSKVEVNGVNLITNKFEGMDMDTLRETADNLRDK
                     LGSGVVVLANVVDDKVNFVVTATKDVLDKGIHSGNIVREVAKIAGGKGGGRPNMAQAG
                     ASDVSKVDQALSYASEVIKTQVK"
     gene            15508..15765
                     /locus_tag="KR294_002167"
     CDS             15508..15765
                     /locus_tag="KR294_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HBH0240245.1"
                     /translation="MEKDLDYTMKFEGIPEDRMSVGDTIDFVYKALVEKGYNPINQII
                     GYLLSGDSSYITSHKNARAIIKKFERDEILEEVITHYLNRK"
     gene            15775..17946
                     /locus_tag="KR294_002168"
     CDS             15775..17946
                     /locus_tag="KR294_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240246.1"
                     /translation="MRKKIMSLFAIVIMIFVSTASYGFAEEKGKVIFIDMNRTNLGSM
                     MNIPILKNEIEKRGYVALMNIRGDQGTDDRRSCASMGAGTRASVTTEDYINFQKVDQD
                     TAKAFEVATGQKAKEINDLGINRSINENLEYGEYGANLGSLGKTLSENGLKTSVIGNA
                     DIIENNQLVKNRNLCLVAMDQYGRIDSGNIDNINKKDSKMPFGISTDYDKLLDETKKS
                     YKNSDAIFVELGDTYRLDMYRLNLNDNTYDTMKKNIVKNINKYLEQVFSMVGENDTVY
                     IASAFPSDLDYKNKRRLSPIIKFSGEGKGLLESATTRKAGIVANLDVGVDILGTFGLE
                     NKEMVGRSYTLVNKEDNISYLKSLYERIVSISSIRSTIINGFVGVISASWVIAMFAIF
                     FRNYMPHKERVFKVLKEFIKLGIIMPLSFMLAPLMNFKTPISISLGIFATTLILYLLG
                     RKLFKDNDIKHMGFFATLTILVIVIDSVFGTYLMQNNIMSYDAVIGARYYGVGNEYEG
                     VTIASAVFGLAVLLHYKKVSKLLVVIFSLIILITSAYPSMGANVGGAISECVAYLLFI
                     MLIYDIKIDFKKAVLLAVSAVVVVFAFAALDILSGSESHLGMFVQRIFLNGPGEILQT
                     FGRKIQMNMQLAQTSVWVNILLVGIGVIAVLIFKPSRHFRKIMNNFPILFKGFIASMV
                     GCIITLLVNDSGIVAASTASIYILIPLIIISINMIIFEKNN"
     gene            18152..18577
                     /gene="ruvX"
                     /locus_tag="KR294_002169"
     CDS             18152..18577
                     /gene="ruvX"
                     /locus_tag="KR294_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HBH0240247.1"
                     /translation="MLDGRIMGLDVGDKTIGVAVSDLMGLTAQGVKTIKRVGKKKDIE
                     ELKAIIKEKQVNKIVSGLPKNMNGTLGPQGEKVIKFCELVKAETGIDVEFWDERLSTV
                     AAERSLLEADVSRQKRKKVIDMLAAVIILQGYLDFKINS"
     gene            18655..18942
                     /locus_tag="KR294_002170"
     CDS             18655..18942
                     /locus_tag="KR294_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HBH0240248.1"
                     /translation="MEENIINLIDENGVESQFEIILTLEAEGKEYAILMPLDDEEAEE
                     ALIFRIDEDEEGEILIPLESDEEYETVVAVYTAIMEEEGLNYDEDESNGLN"
     gene            19224..19682
                     /locus_tag="KR294_002171"
     CDS             19224..19682
                     /locus_tag="KR294_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBH0240249.1"
                     /translation="MANTMDLLKDKLKETGFKITPQRRAIVEILLKHDHSHLSSEEIY
                     DLVRVDCPEIGLATVYRTMQLLDEIGLISKLNLDDGCIRYEISLHKEDCHNHHHLICK
                     NCGKIMEAKEDLLDNIEKEIQSLYKFKILDHDVKFYGLCDECNGVSDSEE"
     gene            complement(19799..20536)
                     /locus_tag="KR294_002172"
     CDS             complement(19799..20536)
                     /locus_tag="KR294_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HBH0240250.1"
                     /translation="MRGKTHCAIGILTAIQTSLIFKIPISLVDILVSATFAVLPDLDK
                     SNSMVSNFILKNNVSKYIYRIFIYAVNIIIFFISININDNFYLSAIITFVAIIIIEAK
                     LTHTFLRKVFLSLIFILLAICLYIIEVEIYFTIFCLMLSIFPWLKHRSFSHSIFATII
                     VYFLLKQIELITNINNLSFYGTIGYASHMFLGDLFTKQGIPIFYPLSEKKISLGFLTV
                     GGPFSNFIEKSFIFVLIGLIIFSILKL"
     gene            20753..22429
                     /locus_tag="KR294_002173"
     CDS             20753..22429
                     /locus_tag="KR294_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HBH0240251.1"
                     /translation="MQLFKKNTNKIKVMALGGLNEVGKNMTVVEYKDEIIVIDAGLSF
                     PEDEMLGVDIVIPDITYLVKNRDKIKGIFITHGHEDHIGALPYILKKINVPVYGARLS
                     IGLIQVKLKEHKMNNVKLNVIGPRQVIKLDNMEVEFLKNNHSIPDAYSIAIHTDQGII
                     YHTGDFKIDLTPIDGDVMDMHRICELSKKGVLLMLADSTNAEKPGFTMSEKTVGVGLD
                     ELFAKGNGRRIIVATFASNIHRLQQIINTAEKFNRKVAISGRSMVNVVGVAKELGYLD
                     ISDDMLIDLNDICKYEDSELVIITTGSQGEPMSALARMAFSEHKKVEIKSGDLVIISA
                     HPIPGNEKLISRVINFLFEKGAEVVYSDIADIHVSGHACQEELKLIHALVRPKFFMPA
                     HGEYRMLKRHAEIAEQLGMDKENIFVMQTGDVLELDKNSAKVANRIQTGNILVDGLGV
                     GDVGNIVLRDRKHLSEDGLMIVVVTISKDEGKVLAGPDIISRGFVYVRESEDLMDGAK
                     DIIKNVLNECEEKNIKEWAYLKNNIKENLKEYLYQKTKRNPMILPIIMEV"
     gene            22637..22837
                     /locus_tag="KR294_002174"
     CDS             22637..22837
                     /locus_tag="KR294_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore protein"
                     /protein_id="HBH0240252.1"
                     /translation="MDDVLRQNAIKALKQTKMEIAGEYGMNYEDAFEIIENASNKGVL
                     EGYFKKLEKKKNLGQGISRHLE"
     gene            22891..24054
                     /locus_tag="KR294_002175"
     CDS             22891..24054
                     /locus_tag="KR294_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HBH0240253.1"
                     /translation="MKKLASTALAILIALTPLSFSFANNKENADANQLNISSKSAILM
                     DVGSGQILYEKDAHKKLPPASVTKVMTMLLIVEALDSGKIKLDDEVQVSETASSMGGS
                     QIFLEPGETQKVDTLLKGIAVASANDACVAMAEHLAGSVEGFVDRMNAKAKELNMNDT
                     HFANTNGLPVANHYTSAHDIALMSRELLKHEMISKYLTTWMDKVVVGKKQVTVGLANT
                     NKLIKHYQGATGVKTGFTQEAKYCLSASAKRGNTHLVAATLGAETSPERFNDASSLLT
                     YGFANYESVKLCSKGDNIATLTLDKADENKVKLVAKEDLNALIKKGSSKEFEKKIEIV
                     KNPKMPIKKGTVLGKIKICKDKKVIGEVELINTKDINKASYLQMLQRIIDNMI"
     gene            complement(24265..24687)
                     /locus_tag="KR294_002176"
     CDS             complement(24265..24687)
                     /locus_tag="KR294_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2000 domain-containing protein"
                     /protein_id="HBH0240254.1"
                     /translation="MENKNSKCVMVIDENLPMGIISNTAAIMGITLGKHAPETVGPDV
                     IDKTGNSHLGIIDIPVPILKGNKEIIKDLRKKLYTLEFNDLTVVDFSDVAQSCNLYEE
                     FTQKIASVPEDELQYFGIAIYGNKKKVNKLTGSMPLLR"
     gene            complement(24708..25544)
                     /locus_tag="KR294_002177"
     CDS             complement(24708..25544)
                     /locus_tag="KR294_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBH0240255.1"
                     /translation="MRQEERTVCFDRELKIEAYRFKGIMQKFPNHFHEHYVIGFIEKG
                     QRYLSCKNKEYTTSTGDLLLFNPFDSHTCEQIDDKVLDYRCINIKPEIMKKTVFEITG
                     KNYLPKFNQPVIFRSELVPLLQELHYIIMEEELDFKKEELFFFLIEQLIEEHTEPNLQ
                     SNLENTNIEIQAVCDYLENNYAEHIILDELSTIAGMNKYSLLRNFTKLKGITPYRYLE
                     NIRVNKAKKLLEKGVEPIDAAIQTGFVDQSHFTNFFKNFIGLTPKQYQNIFINDDSNN
                     FK"
     gene            25842..26438
                     /locus_tag="KR294_002178"
     CDS             25842..26438
                     /locus_tag="KR294_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HBH0240256.1"
                     /translation="MLSMNIGEIVASLVGIAMAISIHEFGHAYSAHLLGDDTAKAYGR
                     MTLNPVRHVDPIGLLAMFILKIGWAKPVPVNPNNFKNYKIGNLIVSLAGVFCNVLTAI
                     LCVIINKYVHMYAINTIAEYVFLYSIGFAAFNLLPIPPLDGWGVISTFVPYKWNEYLY
                     KFESMSYIILLIALFTGMYRIILTPIYAVLLKIVYLFV"
BASE COUNT        10649 a         2797 c         4795 g         8237 t
ORIGIN      
        1 ttaaaagttt ttgtataatt acaaagtata aaaattaata taagttctaa aaagtaagaa
       61 ataagtataa atttattctc atttgataaa gaaaaaaatc taacttgatt atttattata
      121 attagaaata atattatcat agttatgacc ggatacaatg tattttcaac atttttcaaa
      181 tagcttacaa ctaatataaa taaagataaa tatcgtataa aagcaactaa tttttctctg
      241 ttcattaaag gcactcctcc aaaaaaataa acttttacta tgaaaactag aataatatca
      301 taaaagaata aagtcaataa aagtatttat taatattgat ggaaataaaa tcaatccaaa
      361 aacttgaata gtaaaattgt atactgacaa taatttaaaa gtgaaaattt aatgtattgg
      421 agtgaataat gaataataaa gaaaaaggtg attttggaga aaaagtagca gttaattatt
      481 tgctatcaaa aggagcaaag atactagaaa aaaattacag attaaagata ggggaaatag
      541 atataatagc aaaaatggaa gatgaaatta tatttgtgga ggtgaaatca aggtctaaca
      601 taaagtttgg ctacccttgt gaatctgtaa gcttcaaaaa aagaaaaaag ataattggag
      661 ttgcaaatta ttatattata aaaaataact taaataacac tcccgtaaga tttgatgtta
      721 tagaggtata tttattagaa aaaagaataa atcacataat gaatgctttt taaaaaagat
      781 aatgtttttg gaaaggatta aatatgttaa gtattattaa ttcaagcaac ttagtaggaa
      841 tcgacagctt tttagttaag gttgaagtag atgtaagcaa tggaatacct agttttaata
      901 ttgttggtct tccaggcaaa gaaattaaag aagcaagaga aagagtaaag tcagcaattc
      961 ttaatagtgg atataaattt ccaagcacga gaatagttgt aaatttatca ccagcagata
     1021 taaaaaaaga aggagctttt ttagatttat ctataagtat aggcctttta agagagttaa
     1081 taaaaaaaga tgaaaattac ataagagaaa gtatgtttat aggagaatta tcattagatg
     1141 ggaaaataag aaaagtaaga ggtatattgc ccataattat gggtgcaaaa actcagaaca
     1201 taaaacgtat ttttatacca attgagaaca taaaagaaag tctatttgta gatgaaattg
     1261 atataattcc tattaaaagt ttaaaagaat gtgtcgattt tttaaacgaa gagataaaag
     1321 tcgataaagt aaggataatg tcttttttgg atgataagtc aagaaaagag aacgaagaat
     1381 tagaaaaaga taatagttat atagattgca aatatactaa gattaataat gaagaaagta
     1441 aatatgatga agactttaaa gatgtaaaag gaaattattt tgtaaagagg agtgcagaaa
     1501 ttgctgctgc tggaaatcat aatatgttta tgattggacc tccaggctca ggaaaaacta
     1561 tgattgcaaa aagagtaagg acaattttac cagatataag tgtagaagaa atgatagaag
     1621 taagtaaggt ctatagtata ttgggtatga taaatgaaac taaaggaata attgataaaa
     1681 gaccttttag agcacctcat catacaacta caaagcaatc tttaattgga ggaggaatgg
     1741 atgcaagacc tggagaaatt gctttagcac atagaggtat cttattttta gatgagatag
     1801 ccgaatttga tagaaaaata cttgagactt taagacaacc tatagaagat ggatatgtaa
     1861 atatatccag agtaaagtac agtgcaaaat atccttgtag agtactgtta gttgcagcta
     1921 tgaatccatg tccatgtggt tattatatgt cagagacaga gtgtagatgt agaagtaacg
     1981 aaattgatag atacataaat aaaatatcag gtccattgtt agataggttt gatatttttg
     2041 tagaagttaa ttctataaaa tattcagatt ttaattcttt aaaacaagaa gaaagctctc
     2101 aaaaaataaa gagaagagta gaaaatgcta gaaaaataca gataaataga tttaagaagg
     2161 ataatataaa aaataatagt gaaattaaag cttacaattt atttaaatat tgtaaactgg
     2221 aaaaagaagc ttcaaaaacg gctgagatga tatttaataa atacaaccta agcagtagaa
     2281 gttatacaaa acttttaaaa atggcaagaa caatagcaga tttagaagaa agagacttga
     2341 taaattcaca gtgtattata gaagcttttt catttagaaa ggcttattat agttatttta
     2401 aatagttttt tgaggtggat tttatggaaa aaagagatac ttatttatgg ttaaaatcaa
     2461 ttggtggaat aacaacaaaa acaattgaaa taatagaaaa tgaaatagta aatattgaag
     2521 atatatttga tttttctgaa aaagaaatat ataatttaaa aaatataagc ttgaatatta
     2581 gaaaaaatat agtaaaatat agaggtcacg cttatttaga aaatataaaa gaactacttt
     2641 acaaaaaagc gattaaatat atttgtaaat atgataaaga atatcctgaa aatttaaaga
     2701 atatatacaa cgctccaaag ttattattct acaaaggtga cataggctta gttaataata
     2761 attttaatat agctatagta ggttcaagaa aacctacagc ctatggaatt aattgtgcaa
     2821 aaacaataag ttgtcaacta tcccaatatg gagttaatat agtaagtgga ttagctatag
     2881 gaatagatgc atactcgcac ataggttgta tgagtggaaa atctaaaact atagcagtac
     2941 ttggttcagg agtagacaat cctcttccaa aacaaaattt acatttatca aataaaatat
     3001 tagaaaatgg gggattatta ttatcagagt ataatattaa ctcgacagta gccccgtacc
     3061 atttttctaa tagaaataga attatcagtg gtttaagtga tggagtagtt gttgtagaag
     3121 cagcaataaa aagtggtgca ctaatcacag tggattttgc tcttgaacat ggaaaaaatg
     3181 tttttgcaat acctggtaat ataaattctc aaatgagtag aggttgtcat aaaattataa
     3241 aagaaggtgc aaaattaatt gaaaatatag atgatatttt aaatgaatat aacatattta
     3301 atattattga taaaaaaata aatcaaaaat atgataatat aagtctaaat gccaagtcta
     3361 agcaaataat tgaagctata aaaagagaag gaaacttgca tatagatagt atttgtgatt
     3421 atactggtat agaaataaag tatgtaaatt caataatcaa tgaattagta ctaaatgagt
     3481 tagtagtaga aatgaataat aaaacgtaca gtttaaatgt ataaattaag attaggtagt
     3541 gggggtgtat ggttttatgg ccaaaacatt agtcatcgta gaatcgcctg caaaagctaa
     3601 aactatagaa aaatttttag ggaaaagtca ttacacagtt aaagcatcag ttggtcatgt
     3661 cagagattta cctaaaagta aattaggtgt agatatagaa aataattttg aacctcaata
     3721 tataaatata agaggaaaag gcgatgtaat aaaagaatta aaaaaagaag ctaaaaaatc
     3781 taaacaagta tatctagcaa ctgaccctga tagagaaggt gaagctatat catggcattt
     3841 agctcatata ctaaatttag atgaatctga ggattgtaga atagagttta atgagataac
     3901 taaggatgca attaaaaaag caattaaaca tcctagaaat attgatataa atttggttga
     3961 tgcacaacag gcaagaagag tgctagacag acttttaggt tatcaaataa gtcctatatt
     4021 atggcaaaag gttagaaaag gtcttagtgc aggtagagtg caatctgtta caacaaagtt
     4081 aatttgtgac agagaaaaag aaataaaggc atttattcca aaagaatact ggacaataga
     4141 tgttgaggct aagacagtaa aagacaaaga tataactttg aaattttatg gtaaaaatga
     4201 tgaaaagatt gaattagaaa atgaagaagc tgtaaatgaa atactaaaag aaatggaagg
     4261 taaagattta aaggttgaga agatagaatc taaatcaaga cgtaaatcag ctccaaaacc
     4321 atttacaaca agtatgcttc aacaagaagg agcaaataag ttatttttta ctactaaaaa
     4381 aacaatgatg atagcacaag aattatatga aggtatcgac atagaaggtg aaggtactgt
     4441 tggtcttata tcatatataa gaactgactc taaaagaata tctgatgaag caaaagaaaa
     4501 agctaagggc tatatcgtaa acaatttagg agaaaactac tataaaaaca ctggtgataa
     4561 aaaagaaaaa aaggatacta aaaaggttca agatgcccat gaggcaataa gaccaacctc
     4621 agttgataga actcctgaga gtataaaagc ctcattgagc aaagaccagt acaagttata
     4681 caatttaatt tggagaagat ttgtagctag tcaaatggaa gattcagtgt ttgatatact
     4741 aaatgtagaa tgtaaaatag gcgatattgt atttaaggca actggttcaa aaatgaaatt
     4801 tgatggttat accaaggtat ataatttttc agaaagagaa gacaaaattt taccaagtat
     4861 agaaaaagga gatatattaa atatagaaaa tatattgcca gaccaacatt ttacacaacc
     4921 accagcaaga tatacagaag ctagtttagt aaaaacacta gaagaactag gtataggtag
     4981 accaagtacg tatgctccaa caatagctac tatactgaat agagagtatg ttgaaaagca
     5041 aggaacaagt ctatgtccaa cagaacttgg aataatagtt actgatattt tggaaaataa
     5101 tttccataaa tttatagatg tagattttac tgctgatatg gaaagtaaac ttgatgttat
     5161 agaagaaggc aatacagatt ggaaaaagat tgtatcagaa tcatatgcac cacttaaaga
     5221 ggctattgaa gaagctcttg aaaatataga aaaagtaaat atggatgaag aaactgatga
     5281 gatttgcgag aactgtgggt ctaatatggt tatcaaatat ggtagatttg gaaagtttat
     5341 ggcttgtaaa aactatcccg attgtaaaac aactagacca attatgaata aaattggtgt
     5401 taaatgtcca aaatgtgaag aaggagatat tatacttaga aaatctaaaa gaggtaaagc
     5461 tttttatggg tgttctaatt atccaaactg tgactttgta gcttggaata agccaacagg
     5521 agagttttgt gagaagtgtg gttcatatat ggttgaaaaa gtgactaaat ctgaaacaaa
     5581 aacagtgtgt tctaataaag aatgtaataa agagacaaaa gagcataatg acggaaaaga
     5641 gtgaaaattg aaaaaaatca cataattctc ttgaaaaagg ttccaatcta tgataatctt
     5701 tcaagtgtaa acaactaata gaaaaataaa ttttcattaa atgtgaaaat aatattagaa
     5761 aatataaaag gttattaaaa ggcctaaatt tcatgaggag atgattaaat ggcaagtgaa
     5821 gtgttacaaa aaacaaggaa aataaataaa acattacaaa caagtggtgg aagcagtgtc
     5881 tcttttgatt tactggccgg agcattgggc gacgttttaa gttctaatgt ttatgtagta
     5941 agtgcaaaag gtaaagtact aggtcttcat ttaaatgatg ttcaagacag ttcagttata
     6001 gaagatgagt atactaagca aaagaaattt tcagatgaat atactcaaaa tgtgttaaaa
     6061 attgatgaaa cattagaaaa tttaaatggt gagaagatat tagaaatctt tcctgaagaa
     6121 catggaagat tacaaaaata tactacagta gttccaatat taggaagcgg tcaaagatta
     6181 ggaacattgg tactttcaag atattcaaat tcattcaatg atgatgattt agtaatagct
     6241 gaatacagtg caactgttgt tggtcttgaa atattaagag caataggtga agaattggaa
     6301 gaagaaatga gaaagaaagc tgtagttcaa atggcaatag gcactctgtc ctactccgag
     6361 cttgaagcag ttgaacatat ttttgctgaa ttggatggaa aagaaggtct acttgtagca
     6421 agtaagatag ctgatagagt tggtataact aggtctgtaa tagtaaatgc acttagaaaa
     6481 tttgagagtg caggtgtgat agaatcaaga tcattaggta tgaaaggtac tcatataaga
     6541 atacttaatg acaaacttac agatgaatta aaaaaattaa aaaacaatca ataatctata
     6601 ttttataggt ttagattaga aaaggtatct atttcaaata gatacctttt ttagacgaat
     6661 tattaaggta atgataagta tattaaaaag gagtgagaaa atgcctttag cagataaaat
     6721 aagaccaaaa acaatgaatg atgtaatagg tcaaagtcat ataataggta atggaaaaat
     6781 attgtctaag atattacaat ctaatttttt accaaatatg atattttttg gtcctcctgg
     6841 tgttggtaaa actacagtag cggaaataat agcagaaaga agcaataaaa gcttctataa
     6901 aataaatgct actaattcat ctttagaaga tataaaaaag gtgatatcag agcttggaag
     6961 tataaataat gtaaatggag tcctattata tatagatgaa atacaaagtt ttaataaaaa
     7021 acagcaacaa tcaatattag aatttatgga aaatgggagt ataactttga ttgctagcac
     7081 tacagaaaat ccatatcatt atgtatataa agctctttta agtaggtcta ctgtatttga
     7141 atttaaacct ttagaaaaac ttgatgtaga aaaaggactg aaaagagctg ttgaagtatt
     7201 aaatgaagat agctatatgg atattgagtg taataataat gctattgaag atatagcaat
     7261 tctttctgat ggagatatga gaagagcctt aaatatttta gaagtggtag tctattcaac
     7321 taaaccaaat aaggataata taacttatat agattcagat gtaataaggg catctacatt
     7381 taataaaatt ataaactatg acaaaaatgg tgatagtcat tatgatattt taagtgcatt
     7441 tcaaaaatct ataagaggaa gtgacccaca ggcatctata cactatctag caagacttat
     7501 aaaaggtggg gatttgataa gtatatgtag gagactttta gtaatagcta gtgaagatat
     7561 aggtttagct tatccaaatg ctattgtaat tgtaaaggca tgtgtagact cagctatgca
     7621 acttggattt ccagaagcga aaataccatt agcagaagct actattcttt tggctacatc
     7681 tccaaagtct aattctgcat gtatagcaat aatgaaagct atggatgaac tggataaaga
     7741 gtttgttaag gatataccaa atagtataaa ggattctcac tattctggtt ctaaagaaat
     7801 aggtaggggt tgtggataca aatatcctca taattttaaa aatcattatg taaagcaaca
     7861 gtatttacca gatagcataa aagatagtat ttattacata ccacaagaaa ataaaactga
     7921 gaaaaatata aaaaaatatt tagaatatct aaatagtgat ttttagactg aactttatgt
     7981 atcgggggta gatattatga ttataaaact taactcaact tatcacagta gagttatgaa
     8041 atacttaaaa aaagaacctg agtacaattt gtttataata ggggatattg aaagatatgg
     8101 atatggaaat aattttttaa atatatgggc agatgtgggt gaacatggtg aaataaaggc
     8161 aatattactt aaatattttg aatttatgat attttattct gatggagagt atgatgttga
     8221 aggtttttat aatctacttc gtaatactaa ttacgaagaa atatctggga aaatatgtgc
     8281 tgtagatgct ttagcaaaga gattaggact taataattta aaggtagttg atttttgcaa
     8341 acttcaaact aaaaagtttt tgatagataa taattgtaat gcaaaggtta aaagaattag
     8401 gcttggaaat ctaaaaaaga cagtgaaact ttatgactta atagatgaat ttcacagtac
     8461 aactttagag aatttaaaaa atggactaag gacaggtaga ggatattgta tagagattaa
     8521 caaacaggtg gtgtcaatgg caaagagtac ttcagaaaat aggactcatg caatgataat
     8581 tggagtagga acacatccta aatatagagc taaaggactt gctacaaaat gcctaattaa
     8641 actatgttca gagttactga gagaaaacaa aattccttgt ttgttttatg ataatgaaga
     8701 ggctggaaag atatataaaa aactaggatt tgaaaacatt ggaaaatggg gaatttattc
     8761 aaaataaaaa attaaaatta atcttgacaa aattagtagg gtataataaa attatcttga
     8821 aagtaattcc tactaaaaca gtatgaatta gatttctata tagaggtgat aatatatgaa
     8881 gttgtctact aaaggtagat atggactaaa agcaatgttt gaattagcat taaatcaaga
     8941 caatggacca gtatcattaa aatttattgc taagaagcaa aaaatatcag atcagtactt
     9001 agaacaaata ttttcatctt taaaaaaatc gggtctagta aaaagtgtga gaggtgctca
     9061 aggaggttat ttgctttcaa agaatgctga agacataaca gtaggagata tacttgtagt
     9121 attagaagga ccagttgcat tatctgactg tgtactagat gaagatgtat gtgaaaactc
     9181 aaacatgtgt gtaacaaaaa tagtttggga aaagatgaaa aagggtatag aagatgttat
     9241 agattcaatt actcttaaag atatgataaa tgactataac aaaaataaat tagaaaatga
     9301 tataacaaat attaaaaaat agatttggag atgaatgtaa tggaaaaaag aagattgtat
     9361 atggattatt ctgcaacaac acctattaaa aaagaagtat tggatgcaat gatgccatac
     9421 ctaacagatt attttggtaa tgcatctagt tttcacacat tcggaagaga agcaaaagat
     9481 gctttggata aagcaagaga acaagtagca gcccttataa atgctgaacc tagtgaaata
     9541 tattttacag caggtggttc agaaagtgat aactggacac tagagggtgt agcttatgct
     9601 aataaaaaca aaggtaatca tataataact tcaaaaatag agcaccatgc aatacttcat
     9661 acatgtgaat acttagcaaa acatcatgga tttgaaataa cttatttaga tgttgatagc
     9721 gaaggaaaag tagacttaaa gcaactagaa gattcaataa aagatactac tatacttata
     9781 agcataatgt ttgcaaataa tgaaatagga actatacagc ctattaaaga aatatccgaa
     9841 atagctaaaa aacataagat attattccac actgatgcag tacaagctac aggtaatatt
     9901 ccagtagatg ttaaagaatt aggaatagat ttgatgagta tgtcttcaca taaaatatat
     9961 ggaccaaaag gtgtaggagc tttatacata agaaaaggtg taagacttca taactttgtc
    10021 catggtggag cacaagaaaa aagcaaaaga gctggtacag aaaatatacc tgcaatagtt
    10081 ggatatggaa aagcagcaga attagctaag gaaaatatgc aaaatcatgt agaaacttta
    10141 actcgtctta gaaataagtt aatagatggt gtgttagaaa gaatacctta cacaagagta
    10201 aatggtagct tagataatag attgccagga aatgcaaact ttgcattcca atttatagaa
    10261 ggtgaaggaa tacttttatt attagatatg ttaggaattg ctggttcaag tggttctgca
    10321 tgtacttctg gttcattaga cccttcacat gtacttcttg caataggttt accacatgaa
    10381 atagcacatg gttcattaag acttacagtt ggagatttta caacagatga tgatatagat
    10441 tatatactag agaacttacc aaaagtaata gaaagactta gaagcatgtc accactttat
    10501 gatgatgcga agaaacaagg tttagtaaaa tagacataaa gataaagcat aaaaaataga
    10561 cataaattga gtaggaggaa aagataatgc aatatagtga taaagttatg gaacatttta
    10621 tgaatccaag aaatatggga gaaattgata atgcaagtgg tgtaggtgaa gttggaaacc
    10681 ctacatgtgg agatataatg aagatatttt tagacataga tggagatgta ataaaggatg
    10741 ttaagtttaa aacatttggc tgtggttcag ctatagcaag ttcttctatg gcaactgaaa
    10801 tgataaaagg aaaaactata aaagatgcat tagaacttac aaataaagct gttgcagaag
    10861 ctttggatgg tttaccacca gtaaagatgc attgttcagt tttagctgaa caagctgtaa
    10921 aagcagccct tatagattat gctcaaaaga acaatatcca tataccagaa ttggatggat
    10981 atgttataga tgatgctcat gaccatgatg ttgaagaaga agaataaaaa taagtgattg
    11041 tgttatgaga agtttacaat gattaaaaag aagtactaat gatataatta ggacataaaa
    11101 aatagctgtt tttaaaatgg ctatttttta ttgcctaaat taagtatttt aacttgattt
    11161 agaggttaat tagttaacaa aataatccat aagattcaaa taataaagat gattattttt
    11221 ttagaaaata gaacaagcta tattttaaat aagtacaata cttgctctat atggtataat
    11281 aataagtaat gcaaaagatg aggtgaaatt tgtttatgaa taaaaaagta atgataggta
    11341 tgagtggagg agttgatagc tctgtagctg catatctttt aaaacaacaa ggatatgatg
    11401 tcattggtgt tactatgaag ttgtggcaag atgatgatgt tgttgaaatt gaaggtggtt
    11461 gttgctcttt atctgctgtt gaagatgcta gaagggtagc aaataaaata ggtataccat
    11521 tttatgtttt aaattttaga gaagtgttta aagaaaaagt aatagattat tttatagatg
    11581 aatatttgga aggaaaaact cctaatccct gtatagcttg taataaacat ataaaatttg
    11641 atgattttta taagaaggct agacaaatag gttgtgatta tgtagctaca ggtcactatg
    11701 caaagataga aaaggatgaa agtacaggaa gatatttgct aaaaaaatct gttacagata
    11761 aaaaagacca aacttatgca ctttataatc ttacacaaga gcaactagag catactttat
    11821 tgccaatagg tgactatgaa aaagatagag taagagaaat tgctaaggaa atgggtatgg
    11881 cagtacacaa taagcctgat agtcaagaaa tttgttttgt taaagataat gactatgcaa
    11941 attatgtaaa aaaacattct aaaaagcgta ttgaagaagg tttttttgta gatactaaag
    12001 gcaatatact tggaaaacat aagggtatat tatattatac tataggccaa agaaaagggc
    12061 ttggaattac ttttggaaaa ccaatgtttg taatagatat aaatccaata aataatacca
    12121 tagttcttgg agacaatgaa gatttattta aaaaggaact tattgctaaa gatgttaact
    12181 ttatatcaat agatacgtta gaagaaccct taagagttca agccaaaata agatattcag
    12241 caaaaccatc accagctact attcatagag taggagaaga tactattaaa atagtttttg
    12301 atgaagctca aagagctatt actaaaggtc aatctgtagt aatgtatgat ggagatattg
    12361 tagtaggtgg aggtataatc gagaaaagtt tataaaaaca tctaaaaaat taaaaaaata
    12421 agcaataaag tatattaaga gtaaataaag tttataaaat aaatttattg tatatgaaaa
    12481 tatagtattg attaattttg taaaatttag taatataatt agtatattaa ttaaaaaaca
    12541 aatacagtga taaggaatag taaaatattt gatgtcttac agagagaggg aaatgctgga
    12601 agcccttaga atatgatatt tgaagcagcc ttttagtagc aatcttgaac aatttatctt
    12661 ttataaagaa gatttaagta gagattgacg gtagttacgt tatagctaag gttttccgaa
    12721 gatatcatac tttgtatgat aattagggtg gtaccgcgat tgtcctcgcc cctataaatt
    12781 tatttatagg gacgaggttt tttatttaaa cgaaaaaata aaatttatta ggaggaacat
    12841 gatatggaaa agatgggatt aaatgaaata agaagtaagt ttttagaatt ttttgagtca
    12901 aaaggtcatt atgtagcaaa tagttattct ttagtaccaa acaatgataa gagtttgtta
    12961 cttataaact caggtatggc acctttgaaa aactactttt caggtgtaga agtacctcca
    13021 agtgtgagaa tgtgtacatc tcaaaaatgt ataagaacag gagatataga aaatgtaggt
    13081 ataactgcaa gacatgctac attctttgaa atgatgggta atttctcatt tggagattac
    13141 tttaaaagag agtcaatcaa atggggatgg gaatttgtta cagaatggct aaatatacca
    13201 gaagataaga tatgggtgac tgtatatgaa gaagatgatg attcttatga tatatgggca
    13261 aaagaaatga atttcccaga agaaagaatg gttagacttg gaaaagatga taatttctgg
    13321 gaaataggta caggtccttg tggtccttgt tcagaaatat attttgatag aggagaagaa
    13381 tatggatgtg acaatccaga ctgtaaacca ggctgtgatt gtgataggta tttagaattt
    13441 tggaaccatg tatttactca atttgataga gatgaagaag gaaattatag tctattagaa
    13501 aacaagaata tagatacagg tatgggtctt gaaagaatgg gatgtattat gcaaggcgta
    13561 gacactatct ttgaagttga tacaattaaa tctatactag aagcagttga gaagttaaca
    13621 ggagtaaaat atggagagaa tccaaaaaat gatatatcaa taagaataat aactgaccac
    13681 ataagagctg taacattctt agttagtgat ggagtgcttc catcaaatga aggaagagga
    13741 tatgttctta gaagactcct tagacgtgct gctcgtcatg gtaagttatt aggagtaaaa
    13801 gaattatttt tacagaaact aatagatgag gttataaaag taaatgataa agcatatcca
    13861 gttttagttg aaaaagaaag ttatattaaa aaagtagttg gaatagaaga agaaaaattc
    13921 aatgaaacta tagaccaagg aacagaaata ttgaactctt atatagaagt attaaaaaat
    13981 gaaggaaaga ctgtcctaag tggtcaagaa gcttttaaac tatatgatac ttatggcttc
    14041 cctatagact taactaaaga aatattagaa gaagaacatc tatctgtaga tgaagaagct
    14101 tttaatgaag aaatggaaaa gcaaaaagaa agagctagaa atgctagagg aaatatggat
    14161 ggagaaagtt ggaaggaaga ccctctatca aaattagaat ctacagttga cagtacattt
    14221 aatgggtata gtgaaattta tggtgaagga actattgaag ctatagttaa agatgatgag
    14281 ctagttcaaa gtgcagaaga aggcgataag gtatctatag tactagataa cactactttc
    14341 tatcctgaag gtggaggaca agttggagat tgtggattga taactaatga aaacttagtt
    14401 ttagaagtat taaatactaa aaaaggtgct aataatagta taaaacatat aggtataata
    14461 aaatcaggaa gaataagtaa tggggacaaa gtaaagacac tcgtagatag agaaactaga
    14521 atgtcagctg caagaaatca cagtgctaca catttacttc ataaggcatt aagagaagta
    14581 ttaggagaac atgttaatca agctggttct ttagtaactc cagaaagact tagatttgat
    14641 attactcact ttgaagcaat atcaaatgaa gaattaaaag taatagaaga aaaagtaaat
    14701 aatgttattt tatcatcttt agacataaaa tgtgatatta tgaatataaa ggaagctaaa
    14761 gaaaaaggag ctacagcact atttggtgaa aaatatggtg atgaggtaag agtagtttct
    14821 atgggagatt attctacaga actttgtgga ggaactcact tgacaaatac ttctcaagta
    14881 ggaatgttca aaatattatc tgaaggtgga gtagcagcag gtgtaagaag aatagaagca
    14941 ataacaggaa aagctgttta tgaataccta aaagaaagag atggaattat ctctgaagtt
    15001 tgtgtaaact taaaatctaa agaagataat ttaattcaaa gaataagttc tttattagaa
    15061 gaaaataaaa acttatctaa agaattgcat gatatgaaag ctaagatgag tttacaatca
    15121 gttgattcta tttttgattc taaagttgaa gtaaatggag ttaatttgat aactaataaa
    15181 tttgaaggta tggatatgga tacactaaga gaaacagcag ataatctaag agataagctt
    15241 ggttctggtg tagtagtact tgcaaatgta gtagatgata aagttaactt tgtagttact
    15301 gccactaaag atgtattaga taagggaata cattcaggta atattgttag agaagttgca
    15361 aaaatagctg gaggaaaagg tggaggaaga cctaatatgg cacaagcagg agctagtgat
    15421 gtatctaagg ttgaccaagc tttaagctat gcaagtgagg ttattaagac acaagttaaa
    15481 taacattcac tcaaggaggt ttttagtttg gaaaaagatt tagactacac tatgaaattt
    15541 gaaggaatac cagaagatag gatgagtgta ggagatacta ttgattttgt atataaagca
    15601 ttagttgaaa aaggatataa ccctataaat caaattatag ggtatctcct ttctggtgat
    15661 tctagctata taactagtca taaaaatgca agagctataa ttaaaaaatt tgaaagagat
    15721 gagatacttg aagaagtaat cacgcactat ctgaatagaa agtaggtcaa ataaatgaga
    15781 aaaaagatta tgtcgttgtt tgcaatagtc attatgattt ttgtatcaac tgctagctat
    15841 ggttttgctg aagaaaaagg caaggtcata tttattgata tgaataggac caatcttgga
    15901 agtatgatga atattccaat cttgaaaaat gagatagaaa agagaggcta tgtagctctc
    15961 atgaatataa gaggggatca aggtactgat gatagaaggt cttgtgcaag tatgggtgca
    16021 ggaacaagag ctagtgtaac tactgaagac tatatcaatt ttcaaaaagt agaccaagat
    16081 actgctaaag cttttgaagt cgcaacaggt caaaaagcta aagaaataaa tgatttaggc
    16141 attaatagat ctataaatga aaatcttgag tatggagaat atggagcaaa tttagggtca
    16201 ttaggaaaaa ctttatcaga aaatggttta aagacatctg taattggaaa tgctgatata
    16261 attgaaaata atcaattagt taaaaacaga aacttatgtt tagtagctat ggaccaatat
    16321 ggaaggattg attcaggtaa tattgataat attaataaga aagattctaa aatgccattt
    16381 ggaatatcta cagattatga taaattacta gatgaaacta aaaaatccta taaaaatagt
    16441 gatgctatat ttgtagaact tggagataca tatagattag atatgtatag attaaatcta
    16501 aatgataata cttatgatac aatgaagaaa aatattgtaa aaaatataaa taaatatctt
    16561 gaacaagtat tttctatggt tggagaaaat gacactgttt atatagcaag tgcatttcca
    16621 agtgacctag attataagaa taagagaaga ctttctccaa taataaaatt tagtggagaa
    16681 gggaaaggtc tactggaatc tgccacaaca agaaaggctg gaattgttgc caatttagat
    16741 gttggagtag atatactagg tacatttggt cttgaaaata aagagatggt aggtagaagt
    16801 tatactttag taaataaaga ggacaatatt agctatctaa aatcacttta tgaaaggata
    16861 gtgtctatat cttcaataag gtcaactatt ataaatggct ttgtaggcgt aatatctgct
    16921 tcttgggtaa ttgccatgtt tgcgattttc tttagaaatt atatgccaca taaagagcgt
    16981 gtattcaaag tacttaagga gtttataaaa ttaggcataa taatgccact atcatttatg
    17041 ttagctcctt tgatgaattt taaaactcca atttcaatat ctttgggaat atttgcaact
    17101 acgctaatat tatacttgtt aggtagaaaa ttatttaagg acaatgatat aaagcacatg
    17161 ggattttttg caacacttac tattttagtc atagttatag attctgtatt tggaacatac
    17221 ttaatgcaaa ataacataat gagttatgat gctgtcatag gagctaggta ctatggtgta
    17281 ggaaatgaat atgaaggtgt aactatagca agtgcagtat ttggcttagc agtattatta
    17341 cattataaga aggtatctaa attacttgtt gtaatttttt cattaataat acttataact
    17401 agtgcatatc cttcaatggg tgcaaatgtt ggtggagcta tatcagaatg tgtagcatat
    17461 ttgttgttta taatgcttat atatgacatt aaaatagatt ttaagaaagc tgtattatta
    17521 gctgtttcag ctgtagttgt cgtttttgca tttgcagctt tagatatact ttcaggtagt
    17581 gaatctcatt taggtatgtt tgtacagaga attttcctaa atggaccagg agagatatta
    17641 caaacatttg gaagaaaaat tcaaatgaat atgcaactag cacagacaag tgtatgggta
    17701 aatattttac ttgtaggaat tggagtaatt gcagtgctta tatttaaacc atctagacac
    17761 tttagaaaga taatgaataa ttttccaatc ttgtttaaag ggtttattgc atctatggtt
    17821 ggttgtataa ttactctttt agttaatgat tctggaatag ttgctgcatc tacagcatct
    17881 atatatatac ttataccact aataataata agtataaata tgataatatt tgaaaaaaat
    17941 aactaaaaaa atttttactg ttcatatagg atttaaataa aaaatgcaat atgattatta
    18001 atgtaaactg gatgcttaca taaaaaatca tattgcaatt tttatgattg ataatgtaaa
    18061 attctatgaa gcagtaagcc tgtgacctta gttatgagag gttcagaata tgtatttaat
    18121 ctatagaata taaatagata aaggaggaac tatgttagat ggaagaataa tgggtcttga
    18181 tgttggtgat aaaactattg gagttgctgt gagtgatttg atgggattaa ctgcacaagg
    18241 tgtaaaaaca ataaaaagag ttggcaagaa aaaagatatt gaagagctaa aagcaataat
    18301 aaaagaaaaa caagtaaata aaattgtatc aggattacca aaaaatatga atggaacttt
    18361 aggtccacaa ggagaaaaag taatcaagtt ttgtgaattg gtaaaagcag aaacaggtat
    18421 tgatgtagag ttttgggatg agaggctttc tacagtagcg gcagagaggt ctttattaga
    18481 agcagatgtt agtagacaaa aaagaaaaaa ggttatagat atgttggcag cagtaataat
    18541 tttgcaagga tatttagatt ttaaaataaa ttcataaaag aactataaaa ttgaatactt
    18601 atgatatata atataaataa taaaaataaa aataaatttg aggtgaatga cattatggaa
    18661 gaaaatataa taaatttaat agacgaaaat ggcgttgaaa gccaatttga aataatatta
    18721 acattagaag cagaaggaaa agagtatgca atattaatgc ctttagatga tgaagaagct
    18781 gaagaagctt taatctttag aattgatgag gatgaagaag gtgaaatctt aatacctttg
    18841 gaaagtgatg aagagtatga aactgttgta gctgtgtata ctgctataat ggaagaagaa
    18901 ggtttaaatt acgacgaaga tgaatcaaat ggacttaact agataagtaa ttaagtttgt
    18961 atataaaaat cagatattta ttatatttgc tttaattaaa ccttattaat tgtaaaagca
    19021 tttatagtat atatctgttt ttttgttttt tattaaaaat accaaaaaat ttatgaattt
    19081 tggtgaataa tatatctttt atgggtatat atttatatta tgagaataaa ttaaatttat
    19141 ttaaatgtct tgacaaaaaa tgaattatca attacaatat tatttaataa agattatcaa
    19201 ttgaaaatag taagggtgat gttatggcaa atacaatgga tttattaaaa gacaagttaa
    19261 aagaaactgg ttttaagatt acgccacaaa gaagagcaat agttgaaata ttgcttaaac
    19321 atgaccattc acatctaagt agtgaggaaa tctatgattt agttagggtt gactgtcctg
    19381 aaataggctt agctactgta tatagaacaa tgcagctatt ggatgaaata ggattaatat
    19441 caaaactaaa cttagacgat ggatgtataa gatatgagat tagtctacat aaagaagact
    19501 gtcataatca tcatcatctt atttgtaaaa attgtggaaa gataatggaa gctaaagaag
    19561 accttttaga caatatagaa aaagagatac aatcattgta caaatttaaa atacttgatc
    19621 atgatgttaa attttatgga ctatgtgacg agtgtaatgg agtaagcgat tcagaagaat
    19681 aaacttctat tgcttaatgt cgatggaaga atagtataga acttttatat tctatgctat
    19741 tcttccattt tttattataa accatctata aaatgcaaat atacagtttt caaagtgatt
    19801 atagttttaa tattgaaaat ataattaatc ctataagtac aaaaatgaat gatttttcta
    19861 tgaaattact aaatggtcct ccaacagtta aaaaccctaa agaaattttc ttttcgctta
    19921 ggggataaaa aattggtatt ccttgctttg taaataaatc tcctaaaaac atatggcttg
    19981 cataaccaat cgtaccataa aaagataaat tattaatatt agtgattaat tctatctgtt
    20041 ttagtaaaaa atatactatt atagttgcaa atatgctatg agaaaaactt ctgtgcttta
    20101 accaggggaa aattgacaac attagacaaa aaattgtaaa atatatttca acttctatga
    20161 tgtataagca tatagctaat agtataaata ttaatgatag aaaaactttt cttagaaatg
    20221 tatgggttag ttttgcttca ataattataa ttgcaacaaa tgtaattatt gcgcttaaat
    20281 aaaaattatc atttatattt attgaaataa agaaaataat aatattaaca gcatatataa
    20341 aaattctata tatgtatttg gatacattgt tttttagaat gaaatttgag accatagaat
    20401 tagatttatc caaatcgggt agtacagcaa aagtagctga aactaaaata tcaactaaag
    20461 atataggaat tttaaatatt aaagatgtct ggatagctgt taagattcct attgcacaat
    20521 gagttttacc acgcataaat cctcctaaat tatccgatat taaatcatat aatatttaga
    20581 ggatatcaaa ataaaatagg tttgtcaaaa taatacgtta aatgtatttt aaatatagct
    20641 taaaatatga tacgaattat ggtacaataa gaataactgg tagcgagtgc gtgatttgat
    20701 attatttatg attgtagaac gtgttaaaaa attaaataga cagaaggaga tgatgcaatt
    20761 gttcaaaaag aacaccaata agataaaggt aatggccttg ggtggactta acgaagttgg
    20821 aaaaaatatg actgttgttg agtataaaga tgaaataatt gttatagatg ctggacttag
    20881 ttttccagag gatgaaatgt taggagtaga tatagttata ccagatataa cttatttagt
    20941 aaaaaatagg gataaaataa agggtatatt tattacacat ggacatgaag accatatagg
    21001 agctcttcca tatatattaa agaaaataaa tgtacctgta tatggggcaa gacttagtat
    21061 aggtcttata caagtaaaac ttaaagaaca taagatgaat aatgttaagt taaatgttat
    21121 aggtcctaga caagttataa agcttgataa tatggaagta gagtttttga aaaataacca
    21181 tagtatacca gatgcttact ctattgcaat acacacagac caaggtataa tataccacac
    21241 aggagatttt aagattgact tgactcctat tgatggagat gttatggata tgcatagaat
    21301 ctgtgagttg agcaaaaaag gagttctttt aatgctggct gatagtacta atgcagaaaa
    21361 accaggattt actatgtctg aaaagactgt tggggtaggt cttgacgaat tatttgcaaa
    21421 aggaaatggc agaagaatta tagttgctac ctttgcatcc aacatacaca gattacaaca
    21481 aataataaat actgctgaga agtttaatag aaaagttgct atatcaggtc gctcaatggt
    21541 caatgtagtt ggagttgcaa aagaattagg atatctagat atttctgatg acatgcttat
    21601 agatttaaat gatatatgta agtatgaaga tagtgaatta gtgataataa caactggttc
    21661 acaaggtgaa cctatgtcag ctcttgctag aatggctttt tcagagcaca aaaaagtaga
    21721 aataaagagt ggcgatttag ttataatatc tgctcatcca ataccaggaa atgaaaaatt
    21781 aatatcaaga gtaatcaatt tcttatttga aaaaggagca gaagtagtat acagtgatat
    21841 agctgatata cacgtttctg gacatgcctg tcaagaagaa ttaaaactta tacatgcatt
    21901 agttagacca aagtttttta tgccagctca tggtgaatat agaatgttaa aaagacatgc
    21961 tgaaatagct gaacagcttg gtatggataa agaaaatatt tttgtcatgc aaacaggaga
    22021 tgttttagaa ttagataaaa actctgctaa ggtagcaaat cgtatacaaa caggaaacat
    22081 attagttgat ggtctaggag taggcgatgt aggtaatata gttttaagag atagaaagca
    22141 tttatcagaa gatggtctta tgatagttgt agttactatt tctaaggatg agggtaaagt
    22201 tttagcaggt ccagatataa tttccagagg attcgtatat gtaagagaat cagaagattt
    22261 aatggatgga gcaaaggata taattaagaa tgttctaaat gaatgtgaag agaaaaatat
    22321 taaagaatgg gcttatttaa agaataatat taaagaaaac ctaaaagaat atttatatca
    22381 aaaaactaaa cgaaatccaa tgatacttcc tatcataatg gaagtataat ataaaaaaac
    22441 tataaatttg aaaattagac ctcttgtaat ttttaaagta atatcaaaaa tccaattgat
    22501 attatcttaa gaattacaag aggtcttttt aatacttgat ttaaaaaaat atatatatta
    22561 cataaaatac caattataac aatcttttat tagtaaaaac tacttatata taaattttac
    22621 tgataggagg attcttatgg atgatgtttt aagacaaaat gctataaaag ctttaaaaca
    22681 aacaaaaatg gaaatagcag gagagtatgg aatgaattat gaagatgctt ttgaaataat
    22741 agaaaatgcg tctaataaag gtgttttaga aggttacttt aaaaagcttg aaaagaaaaa
    22801 aaatttaggt caaggtatat ctaggcattt agaataaaaa aagttaaatg tgagaaaata
    22861 agtttaaata aactttaaga ggtgacatcg atgaaaaaat tagctagtac tgctttggct
    22921 atattaattg cgcttactcc cttaagcttt tcttttgcaa acaataagga aaatgctgat
    22981 gccaaccaac taaatatatc ttcaaaatca gcaattttga tggatgttgg tagtggacaa
    23041 attttatatg aaaaggatgc tcataaaaag cttcctcctg ctagtgtaac taaggtaatg
    23101 actatgctac ttatagtaga agctttagat tcaggcaaga ttaaacttga tgatgaagtt
    23161 caagtaagtg aaactgcatc tagtatgggt ggtagtcaaa tattcctaga gccaggagaa
    23221 actcaaaagg ttgatacatt gttaaaaggt atagctgttg cttctgcaaa tgatgcttgt
    23281 gttgctatgg ctgaacactt agctggaagt gttgaagggt ttgttgatag aatgaatgct
    23341 aaagcaaaag agttaaatat gaatgatact cattttgcaa atacaaatgg acttccagtt
    23401 gcaaaccact atacatctgc tcatgatata gctttaatgt ctagagaact attaaaacac
    23461 gaaatgataa gtaaatactt aactacatgg atggataagg ttgtagtagg gaagaaacaa
    23521 gttacagtag gtcttgcaaa tactaacaaa cttataaagc attatcaagg agcaactggt
    23581 gttaaaactg gctttactca agaagcgaaa tactgtttat cagcatctgc aaagagaggt
    23641 aatactcatc tagttgctgc aactttagga gcagagactt ctccagaaag atttaatgat
    23701 gcctctagcc ttttaaccta tggatttgct aattatgaaa gtgttaagtt atgtagtaaa
    23761 ggtgataata tagcaacact tacattggat aaggctgatg aaaacaaagt taaattggtt
    23821 gctaaagaag atttaaatgc tcttattaaa aaaggaagtt ctaaagaatt tgagaagaaa
    23881 attgaaatag taaaaaatcc taagatgcca attaaaaaag gaactgtttt aggaaagata
    23941 aagatatgta aagataaaaa agtaataggc gaagtggaat taataaatac taaagatata
    24001 aataaggcaa gctatctaca aatgcttcaa agaataattg ataatatgat ataaataatt
    24061 atcagatgaa atataattat aatacacaaa gatatgatta taatacacat aaaaaatacc
    24121 cttatgtaat tatttgccat aggggtattt ttatttacta tatagaagta ttttataatc
    24181 ttatgatttt tatagaaata tagaaaagtt tatgtatctt aaaatatcat ttgatttaat
    24241 atcatatata gggttgttta acaattatct aagtaaaggc atactaccag taagtttatt
    24301 cactttcttt ttattcccat aaattgctat cccaaaatac tgtaactcat cttctggaac
    24361 actagcaatc ttttgtgtaa attcttcata aagattgcaa ctttgtgcta catctgaaaa
    24421 atctacaaca gttaaatcgt taaattccaa agtatataat tttttacgta aatcttttat
    24481 tatttctttg tttcctttta aaataggtac aggaatgtca ataattccta agtggctatt
    24541 acctgttttg tcaattacat ctggcccaac agtttctggg gcatgttttc ctagtgtaat
    24601 tcccattata gctgctgtat tggatataat tcccattggt aaattttcgt ctattaccat
    24661 gacacatttt gaatttttat tttccatttt tatttctcct ttttacctta tttaaagttg
    24721 tttgaatcat catttataaa tatattttga tactgctttg gtgtaagacc aataaaattc
    24781 ttaaaaaagt ttgtaaagtg actttggtct acaaatcctg tttgtatcgc agcatctata
    24841 ggttctacgc ctttttctaa aagcttttta gctttgttta cccgtatatt ttctaggtat
    24901 ctatatggtg taataccttt taatttcgta aaattacgaa gtagagagta cttattcata
    24961 cctgctatag tgcttaattc gtcaagtatt atatgttcag cataattatt ttctagataa
    25021 tcacatactg cttgaatttc tatatttgta ttttccaagt tagattgcaa atttggctct
    25081 gtatgttctt caattaattg ttcaattagg aagaaaaaaa gctcttcctt tttaaaatcc
    25141 aattcttctt ccatgattat atagtgtaat tcttgtagta gaggtactaa ctcactgcga
    25201 aatataacag gttgattaaa ttttggtaaa taatttttac ctgtaatttc aaagacggtt
    25261 tttttcatta tttctggctt aatattaata catctgtaat caagtacttt atcatctatt
    25321 tgttcacaag tatgactatc aaaagggtta aaaagtagca aatctccagt acttgtggta
    25381 tactctttat ttttacaaga taaatatctt tgaccttttt ctataaaacc aattacataa
    25441 tgttcatgaa aatggtttgg gaatttttgc attatgcctt taaatctata tgcttcaatt
    25501 tttaattccc tatcaaagca tactgtgcgt tcttcttgtc tcacttaggt aacctccttt
    25561 catgttatac aaagtgtaac acatattttt ttatacttct tgtataatat tgactaagag
    25621 acaataatgt caattcatgt caatataata ttacacttac agtaggtgta attattatat
    25681 tttcacaatg aatatgatat aataataaaa gttataaaat aaaaagcaaa ttttaatttt
    25741 atgcctagaa gttaaaatta ttataatgta aaataatttt gattataagc tatttaattg
    25801 ttataataat attaaaaatt taatttagga gatgtacatt aatgttaagt atgaatatag
    25861 gagaaatagt agcaagttta gttggtatag ctatggcaat atcaatacat gagtttggcc
    25921 atgcttattc agctcactta ttgggagatg atacagctaa agcttatggt agaatgacat
    25981 taaatcctgt aagacatgtt gacccaatag gtcttttggc tatgtttatc cttaagatag
    26041 ggtgggcaaa gccagtacca gtaaatccaa ataactttaa aaactataag ataggaaacc
    26101 tgatagtttc acttgcaggc gttttttgta atgttttgac tgctatactg tgtgtaatta
    26161 tcaataagta tgtgcatatg tatgctataa atacaatagc tgaatatgtg tttttatata
    26221 gtattggatt tgcagctttt aacttacttc cgatacctcc acttgatgga tggggagtta
    26281 tatctacatt tgtaccatat aaatggaatg aatatttgta taaatttgaa agtatgagtt
    26341 atataatttt attaattgct ttatttactg gtatgtatag aataatatta acaccaatat
    26401 atgcagtgtt gctaaaaata gtatatttat ttgtttaata taataaacag attaaagagg
    26461 gattgatatg aagtataa
//
LOCUS       DAEPKC010000051        26240 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.051, whole genome shotgun sequence.
ACCESSION   DAEPKC010000051 DAEPKC010000000
VERSION     DAEPKC010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 26240)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26240)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26240
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.051"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(<1..1722)
                     /locus_tag="KR294_002179"
     CDS             complement(<1..1722)
                     /locus_tag="KR294_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH0240257.1"
                     /translation="MMIMIGLEYIKSDIQNIAEAIVSVLNIDVTIVNKELFRIAGTGV
                     YIDKIGEKVDKYTAFKKSLTEQITILIDDPKSSDICRECYKSGACVEFAEVCCPIICD
                     GVSHGVIGLIAFTKEQAQIIENNKSGLINFLGKMADLISNKLKAQIKTYELELEKKKL
                     ETLLNNMDKAVVSIDVDGKIDKYNSKFKELFNIKDSITGKNIFVELDFIKKPSINNFK
                     KDKSCSFFYKRYGYDSKGIYNINKIVLKNELKGYVIDFIDKRDAIKNYNKMNKDYRIK
                     LENIIGESVAIRNSKKEALIASKSTSTVLITGESGTGKELFARAIHNHSNRVDNPFIA
                     VNCAAIPDNLLESELFGYEEGAFTGAKKGGKLGMFEVAHKGSIFLDEIGDMSLHLQSK
                     LLRVLQEKELNKIGSKSNVSIDVRIIAATNKDLEKMVQNGTFREDLYYRLNVIPIKLP
                     SLRERKEDIPLIIKHMVKEYSKKLDKNVIDIDSRVVDAMMEYKWPGNIRELQNIIEYS
                     VNMSSSSIITMNVIPQKIKNTSVEELEVKSDRIIPLDELEKIEIIKALNKYKDYKKDK
                     ELTAKALG"
     gene            complement(1719..1856)
                     /locus_tag="KR294_002180"
     CDS             complement(1719..1856)
                     /locus_tag="KR294_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240258.1"
                     /translation="MEINYELIIIVMLFVILMSIQFTLNKIYLILKEIRQILMLKKNK
                     E"
     gene            complement(1934..2503)
                     /locus_tag="KR294_002181"
     CDS             complement(1934..2503)
                     /locus_tag="KR294_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBH0240259.1"
                     /translation="MKSILCQINKQPVKAKYTSDELECFLDTIEYNVGDKILLVGHIG
                     NLGKRLRGLGTSVTILENSNYEDVCYSLVYNENCNVVKGKLEFLPFDDNQFNKIIIVD
                     QFNVITDCEKASSEIQRVLKGNGEVILEDLNLKNLKVKLNYLKHKFCGSVAKIHYPHE
                     VFNIFSRLNFDGMIKESNKLKYIYVGKRR"
     gene            complement(2687..3322)
                     /locus_tag="KR294_002182"
     CDS             complement(2687..3322)
                     /locus_tag="KR294_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBH0240260.1"
                     /translation="MIAVKDENNVVNLRGELDNKLEFSHEIFGEKFYNMKIKINRLSD
                     SFDILPMTVSERLLQDIDLDKQNLVNVVGQLRSYNKTLNNKNRLVLTVFVREIKSIDE
                     ENKDPNSIFLDGYVCKEPVYRKTPLGREITDLLVAINRPYNKSDYIPSIVWGRNAKFA
                     KNLKVGDRIQLWGRVQSREYEKKIDENNVVKKMAYEVSISKIKKLDENNNE"
     gene            complement(3990..4871)
                     /locus_tag="KR294_002183"
     CDS             complement(3990..4871)
                     /locus_tag="KR294_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TSUP family transporter"
                     /protein_id="HBH0240261.1"
                     /translation="MVAILKALYVVFAAIFAVVFGKDVAKANKEGKLEEQSTPKVAVT
                     GFITDFFDTLGIGSFAPTIAMSKALKLNIPDKKMPGTLNVAHTIPVVTEAFIFTSIIP
                     VDGVTLVSMVVAAAVGSYIGAGIIAKMDERKIQLVMGVTLALTAILMLLGHPWINVLP
                     GGGNELGLTGVKLVIGVIGNFILGALMTAGIGLYAPGMAMVYFLGMSAKVAFPIVMGS
                     CALLMPVASMKFIKEDAYTKKASVIIAICGLIGVFVAAYIVKTLPMDILKALVIVVIA
                     YTSATMIMAANKNKKTA"
     gene            complement(4991..5998)
                     /locus_tag="KR294_002184"
     CDS             complement(4991..5998)
                     /locus_tag="KR294_002184"
                     /EC_number="5.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline racemase"
                     /protein_id="HBH0240262.1"
                     /translation="MKFSRSIQAIDSHTAGEATRIVVGGIPNIKGNSMPEKKEYLEEN
                     LDYLRTAIMLEPRGHNDMFGSVMTQPCCPDADFGIIFMDGGGYLNMCGHGTIGAMTAA
                     IETGVVPAVEPVTHVVMEAPAGIIRGDVTVVDGKAKEVSFLNVPAFLYKEGVEVDLPG
                     VGTVKFDISFGGSFFAIIHASQLGLKIEPQNAGKLTELAMKLRDIINEKIEIQHPTLA
                     HIKTVDLVEIYDEPTHPEATYKNVVIFGQGQVDRSPCGTGTSAKLATLHAKGELKVGE
                     KFVYESILGTLFKGEIVEETKVADFNAVVPKITGSAYITGFNHFVIDEEDPLKHGFIL
                     K"
     gene            complement(6018..6500)
                     /locus_tag="KR294_002185"
                     /pseudo
     CDS             complement(6018..6500)
                     /locus_tag="KR294_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428088.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase"
     gene            complement(6518..6985)
                     /locus_tag="KR294_002186"
     CDS             complement(6518..6985)
                     /locus_tag="KR294_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase"
                     /protein_id="HBH0240263.1"
                     /translation="MGIGPSTKETSLHHFRDPLLDIVESDKDVDLLGVIVVGTPDGNE
                     NKTFVGQRTAAWLEAMRVDGAIVSSDGWGNSHVDYANTFEEIGKRDIPVVGVTFNGTQ
                     AKFVVSNQYMDTIVDMNKSKEGIETEVVGENNTNEIDAKKALAFLKLKMRKHG"
     gene            complement(7000..7758)
                     /gene="prdD"
                     /locus_tag="KR294_002187"
     CDS             complement(7000..7758)
                     /gene="prdD"
                     /locus_tag="KR294_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase cluster protein PrdD"
                     /protein_id="HBH0240264.1"
                     /translation="MEEKIMRRLVIKPFHMNEVNFGSKTSIKKDVLTIDLSSIDEIKE
                     REELITDIKVDIIKPGDYDREINTIMDIIPISTKVLGRLGEGITHTLTGVYVMLTGAD
                     EDGNQMHEFGSSEGILKDQMVFGRYGTPSVEDYIIHVDVTLKGGLPFERTLPLAAFRA
                     CDDFIQEIRASLKMEDGRNATQVREYFDKIRPNAKKVVIVKQIAGQGAMYDNQLFSKE
                     PSGFEGGTSIIDMGNVPMIISPNEYRDGALRAMT"
     gene            complement(7838..8563)
                     /gene="prdB"
                     /locus_tag="KR294_002188"
     CDS             complement(7838..8563)
                     /gene="prdB"
                     /locus_tag="KR294_002188"
                     /EC_number="1.21.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:complement(8111..8113),aa:Sec)
                     /transl_table=11
                     /product="D-proline reductase (dithiol) protein PrdB"
                     /protein_id="HBH0240265.1"
                     /translation="MSLTTVQGLQSEIFVPITPPPVWTPVTKELKDMTIALATAAGVH
                     LKSDKRFNLAGDTTFRAIPNTATVDEMMVSHGGYDNGDVNKDINCMFPIDRLHELAAE
                     GFIKGVAPMHYAFMGGGGNQHVFTEETGPAIAAKLKEEGVDGVVMTAGUGTCHRTAVI
                     VQRAIEEAGIPTIIIAALPPVVRQNGTPRAVAPLVPMGANAGEPHNIEMQTHILRDTL
                     EQLVAIPSAGKIVPLPYEYKAHV"
     gene            complement(8601..8885)
                     /locus_tag="KR294_002189"
     CDS             complement(8601..8885)
                     /locus_tag="KR294_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240266.1"
                     /translation="MDRLKYISSETFYEGIIVDIKGGGVTIDLKGRLGQFKIPNRMLI
                     TDYELKIGQEVGFMLSYPEVLSPEPNQEYVENIRREKEKQAEMQSKQEEK"
     gene            complement(8966..10846)
                     /gene="prdA"
                     /locus_tag="KR294_002190"
     CDS             complement(8966..10846)
                     /gene="prdA"
                     /locus_tag="KR294_002190"
                     /EC_number="1.21.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-proline reductase (dithiol) proprotein PrdA"
                     /protein_id="HBH0240267.1"
                     /translation="MSITLETAQAHANDPAVCCCRFEAGTIIAPENLEDPAIFADLED
                     SGLLTIPENGLTIGQVLGAKLKETLDALSPMTTDNVEGYKAGEAKEEVVEETVEEAAP
                     VSEAAVVPVSTGVAGETVKIHIGEGKNISLEIPLSVAGQAGVAAPVANVAAPVASAAA
                     EVAPKVEEKKLLRSLTKKHFKIDKVEFADETKIEGTTLYIRNAEEICKEANETQELVV
                     DMKLEIITPDKYETYSEAVLDIQPIATKEEGELGSGITRVIDGAVMVLTGTDEDGVQI
                     GEFGSSEGELNTTIMWGRPGAADKGEIFIKGQVTIKAGTNMERPGPLAAHRAFDYVTQ
                     EIREALKKVDNSLVVDEEVIEQYRREGKKKVVVIKEIMGQGAMHDNLILPVEPVGTLG
                     AQPNVDLGNMPVVLSPLEVLDGGIHALTCIGPASKEMSRHYWREPLVIRAMEDEEIDL
                     VGVVFVGSPQVNAEKFYVSKRLGMLVEAMEVDGAVVTTEGFGNNHIDFASHIEQIGMR
                     GIPVVGVSFSAVQGALVVGNKYMTHMVDNNKSKQGIENEILSNNTLAPEDAVRIMAML
                     KNAIEGVEVKAPERKWNPNVKLNNIEAIEKVTGEKIVLEENEQSLPMSKKRREIYEKD
                     EN"
     gene            complement(11275..13035)
                     /gene="prdR"
                     /locus_tag="KR294_002191"
     CDS             complement(11275..13035)
                     /gene="prdR"
                     /locus_tag="KR294_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54 dependent transcriptional regulator
                     PrdR"
                     /protein_id="HBH0240268.1"
                     /translation="MFSIPEVKKVEEVMDTKFTTIDEDTRIEDAIKEMIKSNTKTLMV
                     IDSSDQLKGIISMTDIHNLYEMHKKYEGQPVKLIMKKDVIYVNEGLTLDECRDIMILK
                     NIGILPVLRDNKIIGVLKQEHIRDYLYMHLEDYGLTLKYIIGQIKEGICAINNEGVVI
                     LWNKFMEERYDIKSEDIVGRPMNEFLENTISEKVLNSKVGMSDLYFTDKKENMYALVH
                     ANPIFYKEEFIGVVCTEVDVTEAKILALELEKVNDTLKYLKNEVKNLSKGSFDKILGK
                     SYKLEKSKAIAKQVARTNSSIFIWGESGTGKEVFARAIHDYSERKGQFIPVNCSAIPN
                     ELFESEFFGYESGAFTGASKKGRIGIFELAKDGTVFLDEIADLPLSMQAKLLRVLQEK
                     EIRRVGGDTTIKINPRIISATNKDLSKMVKAEKFREDLYYRLNVVEIKIPPLRERKED
                     IGLLVHSFLEEICKQNNKPVLTISKDVIDIFQNYRWKGNIRELKNTIENIVVLSQNSK
                     IDVDDVPSYMMDSTNNSTEEEEYPLDLTKATQKIEIKNITKALKMSNGNKAKAAKILN
                     IPRTTLYYKIDQYKIDVSKI"
     gene            complement(13442..15691)
                     /locus_tag="KR294_002192"
     CDS             complement(13442..15691)
                     /locus_tag="KR294_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-Gln thioester bond-forming surface protein"
                     /protein_id="HBH0240269.1"
                     /translation="MKTKIKKSSIISLVIAFSMVFTAFTPIVSYADEVTSNDTILNGE
                     EQSNGQTSDVEKPSDGQVPDGEKPSDSQVPDVEKPSDGQVPDGEKPSDSQVPDGEKPS
                     DGQVPDGEKPSDGQIPDGEKPSDGQIPDGEKPSDGQIPDGEKPSDGQMPDGEKTSDSQ
                     TPDVEKPSDGQMPDGEKPLDEQTPEEEKPLEEEIVIEEMSLKQDIDKILDMTLSQINK
                     IVYNFWEDEEDVKADEQSEINQVFTSEDSFISLWYDKKAKVKNSCLLKEIDGSDRPYH
                     DLRFDDITKTLTFDYVIKGLVGASSKDDKYVIEGEDGEQTAFCYNNHLRPPSSNGKSP
                     YLPAEDFNGQENQNEEAVKSILYAGSEFDGFGYKQQFNLGGEENELMTYSATQSAIWI
                     ILGQMDEQERLKQYQGSINLCDKLIERAKTEEERAEYQKKKEVAINIKAYLEALLKAG
                     REELKPNNTGKPSLSNGLTKINFEKNEDGTYETEAVALVGYSGVVKLKLPDGVTAYDG
                     DGNIIGTGEVEISTQQKFKLKSVGKPDAKANISAVSYDYIFPKAIQYYKAVLDLGQKD
                     HSSSLPSSKQNLLSYTIEKKNGQEVNFNIGLPTDDDDVVNPPVPPIDDDVVNPPVPPT
                     DDTNGHKPKPSPPIDDTVINPPVPPMDDTIINPPVPPTEDAVLNPPVPPMEDAVLNPP
                     VPPTEDTVLNPPVPSVSDTVEKTPELSRDDTIIKSPKTGDETQLMSYVFISVIAICGL
                     AYQCKIKRN"
     regulatory      complement(16273..16358)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            complement(16762..18075)
                     /gene="prdC"
                     /locus_tag="KR294_002193"
     CDS             complement(16762..18075)
                     /gene="prdC"
                     /locus_tag="KR294_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase-associated electron transfer
                     protein PrdC"
                     /protein_id="HBH0240270.1"
                     /translation="MNKLYSILLKQHVGGPDKPVVSVGDVVKKGTLIAEPTGLGANIY
                     ASVSGKISEINDQAIVIEADEVQEDTFEPLKGEGILDLIKEAGVVGMGGAGFPTHVKL
                     NIDLNGGTILANAAECEPLLAHNIKEIEERPEIVYQGIKYAMEVTNAGKGMLAIKSKH
                     PKAIEAFKKVIKPGDNIEVAELVDMYPMGEERAIVRDVLGKLLEPTQLPSEANAVVIN
                     VETLTRIVEAVEQKRPVISKNITVVGQLNSGKESIVFEDVPIGTTVGELIERAGGIKG
                     EYGEIILGGPFTGKATTLDAPITKTSGGIIVTMPFVNEKRKMGLLVCACGPNEERMRD
                     IATKMGVTDIVSVQKCKQAQEIKGALKCENPGHCPGQAQKCIEFKKAGAEVILIGNCT
                     DCSNTVMGSAPKLKLGVYHITDHVMRTVNHPLIRRIKGDVRLKIK"
     gene            complement(18464..19228)
                     /locus_tag="KR294_002194"
     CDS             complement(18464..19228)
                     /locus_tag="KR294_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBH0240271.1"
                     /translation="MKREVKRTKALIYSVLFFSLLLVLIFVFVYGIKYICSKSDNSKM
                     PIYKVDTNEKKIALSFDVAWGTDNMDDILKILDKHNVKATFFLVGSWVDDNEEIVKAI
                     DEKGHEIGNHSNTHANLKEISKEDITKEIETTSEKIYNITGKRTNLFRPPFGDVNNKA
                     MDICSDLGYKVIKWDVDSIDWKELGPNHVIEKVIKESQPGSIVLFHANINDVDNYLDT
                     IISRLKKDGYSLVKISDLLYKDNYVVDSNGVQKTKN"
     gene            19519..19722
                     /locus_tag="KR294_002195"
     CDS             19519..19722
                     /locus_tag="KR294_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta-type small acid-soluble spore
                     protein"
                     /protein_id="HBH0240272.1"
                     /translation="MSNSNRTVVPEAKAALNQMKLEIANEIGLSNYENIDKGNLTARE
                     NGYVGGYMTKKLVEMAERQMAGK"
     gene            19913..20449
                     /locus_tag="KR294_002196"
     CDS             19913..20449
                     /locus_tag="KR294_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4364 family protein"
                     /protein_id="HBH0240273.1"
                     /translation="MFENSSEELAYHKLLILYILEKIKMDLTNSQITQVVLETEMMNY
                     FSLQQLLSQLMESKFLTTYKDSDREYYALTQRGVESLEYFFNRIPTSVTEKIDKYIDS
                     NKENLLADTQVKSSFVKQSDNEFIVNLRVIENQSNLIDLNLNVSSEKQAKLICNNWKN
                     NASYMYAEVIDLLIRDIH"
     gene            complement(20453..21319)
                     /locus_tag="KR294_002197"
     CDS             complement(20453..21319)
                     /locus_tag="KR294_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YncE family protein"
                     /protein_id="HBH0240274.1"
                     /translation="MKIYISNYLSKSISIVDYSTLELEKEIVLEDNIYPHHFCIEKEK
                     NLIYIPSSSNGILYVLDLSNDKIIDTVSIGGSLSQVVLSDNELFVANEDSNSIYVLDK
                     NTLNPIGIIGVDNMPHGFDFDRESKKLYVPCINSIVCIDTINKNIQKKINMDFRAWHI
                     ELDKQKKEMYISTLDGKLIIIDEVSMDIKKVLYEFLLPVEIRFNYSGKKVYVADLGYN
                     NVRILDYTTSRYIGNIEINGIPQGLEISKDEKLLFVSDTQENSVKVYETANNKLIKEI
                     KVGKEPTTIICL"
     gene            21467..21712
                     /locus_tag="KR294_002198"
     CDS             21467..21712
                     /locus_tag="KR294_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03905 family TSCPD domain-containing
                     protein"
                     /protein_id="HBH0240275.1"
                     /translation="MKVTFNPSGVCCREMIFEVDENNVIVDAEFIGGCNGNLSGLRSL
                     IIGQNALEVADKLNGIDCGGKGTSCPDQLSKAIRQSI"
     gene            complement(21826..23124)
                     /locus_tag="KR294_002199"
     CDS             complement(21826..23124)
                     /locus_tag="KR294_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HBH0240276.1"
                     /translation="MKYEEALEYISQTNKFGIRLGLENIGKLLELLGNPQETLNIIHV
                     AGTNGKGSVCSFVSNILRECGYKVGLYTSPYLETFTERIRVNGQNIPQDDVARIIELI
                     KEKIEIMVKEGYAYPTEFEVVTAMAFYYYSEQKVDFVALEVGLGGRYDATNIITKSLV
                     SVIVSISLDHTGILGDTIEKIAYEKAGIIKENGVVLVYDQTDEAKDVIKSVCKEKKAK
                     YIEVDFDDINIKKSDINSQIYDCTVMKETYRDLEIKLIGEHQINNSILAISVIKYLKD
                     INKLANINEESIRKGLINTKWPGRIEKIKENPIFIIDGAHNEDGAKSLAKALDKNFKG
                     RKLTLLIGMLEDKDIDSVLEILLPHFNKVITTTPSNPRAINSDILREKVLKYVDDVTS
                     KHEIEDAVNYTLETSSEDDIIISAGSLYMIGTVRTLVKKL"
     gene            complement(23257..24288)
                     /locus_tag="KR294_002200"
     CDS             complement(23257..24288)
                     /locus_tag="KR294_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HBH0240277.1"
                     /translation="MENICDMNNKVKVAVLDTGIDKEHDYLKDNLVGGIAFECMHDYI
                     FISDKFDDEDGHGTACASIIKKEYEDVELFVIKILRKDGITNIKVLEEALRYLLDTNI
                     RLINLSLSVIGVESVKGLFEVCYELFRKGKIIVCSLANDFDLSYPAMFNNVIGVRGFT
                     LDGDDSFWYNKKYDVQCVMDSNSYISCDINNSYRLPPKCNSYLSAKLTGKIAKILSEK
                     PGITISDLNDKLESLATRNHWDSCDFDECSRIVNFKLDLYDKENALFMKVADVVRDCL
                     DIEENNEKLFKGSLFNKEIGLVYDNCFNLLKKLEHRFDIKFNYMDISKYDLVSIYTLT
                     ELVERYKNL"
     gene            complement(25334..26044)
                     /gene="rgaR"
                     /locus_tag="KR294_002201"
     CDS             complement(25334..26044)
                     /gene="rgaR"
                     /locus_tag="KR294_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RgaR"
                     /protein_id="HBH0240278.1"
                     /translation="MFRVVICDDEKIQRSILKEFTEKLLSERCLNYQILEFSCGEDLI
                     SKYPEKIDIIFLDIQMKDINGIEVAKKIRKFDEKVEIIFTTAFSEYAPQGYEVRAYRY
                     LVKPIEYSNFAMGVNLCIDNLQRKKERYIVLNSKKGFNRILIDSILYVETVKRDLVVH
                     TIGRDYKANMSMKQAEKLLCENGFFRCHTSFIVNLRRIEDLRDNTITINEQFIPISKY
                     RLKDLKVALTSLLCDIMY"
BASE COUNT         8039 a         4751 c         2897 g        10553 t
ORIGIN      
        1 tccaagtgct ttagctgtta attctttatc ttttttataa tctttgtact tatttaaagc
       61 ttttattatc tcaatcttct ctagttcatc aagtggaatt atcctatcgc ttttaacttc
      121 taactcttct acagaggtat tcttaatttt ttgaggaatt acattcattg taattattga
      181 agaagaagac atattcacac tatattcaat aatattctgc aactctctta tattccctgg
      241 ccacttatat tccatcatag catcaacaac cctgctatct atgtcaataa catttttatc
      301 taattttttt gaatactctt taaccatatg cttgattata agtgggatat cttcttttct
      361 ctctcttaaa cttggtaatt ttataggtat aacatttaat ctatagtata aatcttctct
      421 aaaagtgcca ttttgaacca ttttttctaa atctttattt gtagcagcaa taattcttac
      481 atctattgaa acatttgatt tacttccaat tttattaagt tccttttctt gtaatactct
      541 caataacttt gactgtaaat gcaaactcat atctcctatt tcatctaaaa atatacttcc
      601 cttatgagct acttcaaaca ttccaagctt tccacctttt ttagctccag taaaagctcc
      661 ctcttcatat ccaaataatt cactttctaa taaattgtct ggtatagcag cacagtttac
      721 agctataaaa ggattatcta ctctattgct atggttgtgt atggctcttg caaatagctc
      781 cttacccgtt ccactttccc cagtaataag tactgttgat gttgatttag aagctattag
      841 ggcttccttt ttagaatttc ttatagctac actttctcca attatgtttt ccaattttat
      901 tctataatct ttattcatct tattgtagtt ttttatagca tctcttttat ctataaaatc
      961 aataacatat ccctttaact cattttttaa tactatttta ttgatgttgt atattccctt
     1021 cgaatcatat ccgtatcttt tataaaaaaa actacaggat ttgtctttct taaagttatt
     1081 tatagaaggt ttctttataa aatctaattc gacaaatatg tttttgccag ttatactatc
     1141 ctttatattg aaaagctctt taaattttga attatattta tcaatttttc catccacatc
     1201 aatagacaca acagctttgt ccatattgtt taacagtgtc tctaattttt tcttttctaa
     1261 ttcaagctca taagttttaa tttgagcttt taatttatta gatattaagt ctgccatttt
     1321 gcctaaaaag tttataagac cacttttatt attttctata atctgtgctt gttcctttgt
     1381 aaaggctata aggcctataa caccatgaga gactccatca catataatgg gacaacacac
     1441 ctctgcaaac tctacacaag ccccactttt atagcattcc ctacatatat cactactctt
     1501 tgggtcatca attagtattg taatctgctc tgtaagtgat tttttaaaag ccgtatattt
     1561 atctactttc tcacctattt tgtctatata tactcctgta cctgcaatcc taaataactc
     1621 cttatttact atagttacat ctatattgag tactgatact atagcttcag ctatattttg
     1681 aatatcagat tttatatatt ctaaacctat cataatcatc attccttatt tttctttaac
     1741 ataagtattt gtcttatttc tttaagaatc aagtatatct tatttaaagt aaattggatt
     1801 gacatcagga ttacaaagag cataacaatt attattaact cataatttat ttccatctaa
     1861 acatctcctt ataacaaaag actaggctta acctagtctt ttatattata tccatattta
     1921 tattttaact catttatctt ctttttccca cataaatata ttttaattta tttgactctt
     1981 taatcatacc atcaaagttt aatcttgaaa atatattaaa tacttcatgt ggatagtgaa
     2041 tctttgcaac agaaccacaa aatttatgtt taagatagtt taacttaact tttaaattct
     2101 ttaaatttaa atcctctaat ataacctctc cattgccctt taacactctt tgtatttcag
     2161 atgaagcttt ttcacaatct gtaataacat taaattggtc aactattatt atcttgttga
     2221 actgattatc atcaaatggt agaaactcta acttaccttt aactacattg caattttcat
     2281 tatacactag agaataacag acatcttcat aattactatt ctccagtata gttacagaag
     2341 ttccaagacc tctcaatctc ttgcctaggt ttcctatatg accaacaagc aatattttat
     2401 cacctacatt atactcaatt gtatccaaaa aacattctaa ttcatcagat gtatatttag
     2461 ctttaaccgg ctgtttattt atctgacata atatgctttt cacaatgctt cacctcttca
     2521 tttcctcaat tataaattat gtacagatta cattataata aatggcgagc aactattcaa
     2581 gagatatttc attagtattt ttttaaacaa tctttataca ttttaatatg atattatacc
     2641 aaatttatta ggattttatt cataaaaatc agtctatttt ttatgtttat tcattgttat
     2701 tttcatccaa tttttttatt ttcgatatgg atacttcata tgccattttt ttgaccacat
     2761 tattttcatc tatttttttc tcatattctc tactttgaac cctaccccaa agctgtattc
     2821 tatcaccaac ctttagattc tttgcaaatt tagcatttct accccaaact attgatggta
     2881 tataatcaga tttattataa ggtctgttta tagcaactaa taaatcggtt atttcccttc
     2941 ctaaaggtgt cttcctatac acaggttcct tacatacata tccatctaaa aatatactat
     3001 tagggtcttt attttcctcg tctatgcttt ttatttctct gacaaacact gtaagcacta
     3061 atctattttt attatttaat gttttgttat atgatcttaa ttggcctacg acattgacta
     3121 aattttgttt atcaaggtca atatcttgga gaagtctttc tgatacagtc attggaagta
     3181 tatcaaaaga atcgcttagt ctgtttattt ttattttcat attataaaat ttttctccaa
     3241 atatctcatg gctaaattct agcttattgt ctaactcccc tcttaagttt actacgttat
     3301 tctcatcttt aacagctatc atattttatc cctccacaat tgttaattct tatatttctg
     3361 gtatcagctt atataataaa tatatttata agggatgtat tttattacaa atctttgatt
     3421 gctgtttaaa agtttttatt tagttataaa tttcatttaa tatttcactt ttataattat
     3481 aaaattatta tctttttgta ccacatatac taattaaact acctatttca gttttgtatt
     3541 aattataaaa atcctattat atagttaata agtcatatat aacttaaatt tattcactct
     3601 atataagcaa cttcaacgaa ttaaatttat tcaaataatt cagatgaata ttgagtcatt
     3661 ataaacttat ttttcttaat tataagttat attagactta ttataggtta tatttttatt
     3721 aatctgtatt aatatatgaa catttattga acttattgat tataaaattt aaatatttag
     3781 ctttaaatta tgctttattc tttaaaaata caacgttttt tacattaaat ctactaaatc
     3841 actatatata ttacataatt ggcatgttaa ttgctttata ttaatttagt aaataaaaaa
     3901 ctgccctaaa atattaattc aatattttaa agcagtttat aatctttatt attagctgta
     3961 atatttaata aacactaagt agtctttaac taagcagtct ttttgttttt atttgcagcc
     4021 attatcattg tagcagaagt ataagctata actactatta ctaatgcttt taatatatcc
     4081 attggtagag tttttactat atatgcagct acgaaaactc ctattaaacc acatatagct
     4141 attataactg atgctttttt agtatatgca tcttctttta tgaatttcat acttgcaact
     4201 ggcattaata atgcacaaga acccataact attgggaatg caacttttgc agacattcct
     4261 aagaaataaa ccattgccat acctggagca tataaaccta taccagctgt cattaaagct
     4321 cctagtataa agttacctat tacacctatt actaatttaa caccagtaag acctaattca
     4381 tttcctccac ctggtaatac gttaatccaa ggatgaccta ataacattaa tattgctgtt
     4441 aatgctaaag ttacacccat aacaagttgt atttttctct cgtccatctt agctattatt
     4501 cctgcaccta tatatgaacc aactgctgct gccacaacca tagatactaa agtaacacca
     4561 tcaactggta tgattgatgt aaatatgaat gcttctgtaa caactggaat agtatgtgct
     4621 acgtttaatg taccaggcat ttttttatct ggtatattta actttaaagc ctttgacatt
     4681 gctattgttg gagcaaatga ccctattcct aatgtatcaa agaagtctgt tataaatcct
     4741 gttacagcaa cttttggagt actttgttct tctagtttcc cctctttgtt tgctttagct
     4801 acgtctttac caaacacaac tgcaaagatt gctgcgaata ctacatataa tgcctttaag
     4861 attgctacca taatccatcc tcctattttt ttattttttc atatattctg aatcttatag
     4921 cctaaaagct atagaatagc aaccgacaag tggctactat tctattttaa tttcctaatt
     4981 tatttattac ttatttaaga ataaatccat gtttaagtgg gtcttcttca tctattacaa
     5041 aatgattaaa tccagttata taagcagaac cagttatttt aggtactaca gcattgaaat
     5101 ctgcaacttt agtttcttca actatttcac ctttgaataa agttcctaat atactttcat
     5161 atacgaattt ttctcctact tttaattcac ctttagcatg taaagtagct aatttagcac
     5221 ttgttccagt tccacatgga gatctgtcaa cttgaccttg accaaatata actacatttt
     5281 tgtaagtagc ttctggatga gttggctcat catatatttc aactaagtct acagttttta
     5341 tatgagctaa agttggatgt tgtatttcta ttttctcatt tattatatct ctaagtttca
     5401 tagctagttc agttaattta ccagcatttt gaggttcgat ttttaaacct aattgacttg
     5461 catgtattat agcaaagaag cttccaccaa atgatatgtc aaatttaaca gttccaacac
     5521 ctggtaagtc aacttcaaca ccttctttat ataagaaagc tggtacgttt aagaatgata
     5581 cttctttagc ttttccatct acaactgtaa cgtctcctct tattattcct gctggagctt
     5641 ccataactac atgagttaca ggctctactg ctggaactac acctgtttct atagctgctg
     5701 tcatagctcc tattgtacca tggccacaca tgttaaggta tccgccacca tccatgaaga
     5761 ttattccaaa gtcagcatct gggcaacaag gttgagtcat tacagaacca aacatatcat
     5821 tatgtcctct tggctctaac attatagcag ttcttaaata atctagattt tcctctaaat
     5881 attctttttt ctcaggcata gaatttcctt ttatgttagg tattccacct acaactattc
     5941 tagttgcttc acctgctgta tgagagtcta tagcttgtat acttctgcta aatttcatat
     6001 caaattcccc cttaggttta ttttgcgtct ttacgcattt ttaattttag gaaagccaat
     6061 gcttttttaa catcaacttc atccatgtga ttgtctccaa ctacttctgt ttctatgtag
     6121 cctgttgtct ttttataatc aattatggta gctttatcca actatggatt ggtaattact
     6181 aatccatctg ctcccataat agtaagacct actgtaggta tatctgattt tacaaactct
     6241 gctatagcat ttgtaaaatc aatgtgctgg tttcctgcca tatctaaagt tataatcact
     6301 ccatcaggtc gcaatgattc aatccatctt ccaagtctag ttgctaaaaa tgttttccat
     6361 tcattgtgct ctgatgtccc aactacaacc actcctaaca agtctatgtc agaatcatta
     6421 tctatcaaat ctagtaacgg gtctctaaat atatgaagtg atgtgttttt cattgatgta
     6481 gaaattccca caaaactcat tcccttactt aaatttttta tccatgtttt ctcattttaa
     6541 gttttaaaaa tgccaaagct tttttagcat ctatttcatt tgtgttgttt tctccaacta
     6601 cttctgtctc aataccttct tttgatttgt tcatatcaac tatggtatcc atatattgat
     6661 tgcttacaac aaacttagct tgagtcccat taaatgtaac tccaactaca ggtatatctc
     6721 tttttcctat ttcctcaaat gtgttagcgt agtcaacatg tgagtttccc caaccatctg
     6781 atgaaactat agctccatct actctcatgg cttccagcca agcggccgtt ctttgtccca
     6841 caaaggtttt attttcattt ccatctggag ttcctactac tattactcca agtaaatcta
     6901 catccttatc actttcaact atgtctaaaa gtgggtctct aaagtgatga agagatgttt
     6961 cttttgttga aggtcctatt cccataatat ccacctctct taagtcatag ctctaagggc
     7021 accatctctg tattcattag gagatataat cataggtaca tttcccatat ctataattga
     7081 tgttcctcct tcaaatccac taggttcctt tgagaataac tgattgtcat acatagcacc
     7141 ttgacctgct atttgtttta ctatgacaac cttttttgca tttggtcgaa ttttgtcaaa
     7201 atattcacga acttgagtag catttcttcc gtcttccatt ttcaaagacg ctcttatttc
     7261 ttgtataaaa tcatcacatg ctctgaatgc tgcaagtgga agtgttcttt caaaaggtaa
     7321 acctcccttt aaagttacat ctacatggat tatataatct tcaactgatg gagttccata
     7381 tctcccaaat accatttggt ctttcaaaat tccttctgaa gaaccaaatt catgcatttg
     7441 atttccatct tcatctgcac cagttaacat tacatataca cccgttaaag tatgtgtaat
     7501 accctctccc agtctgccta aaacttttgt tgatattggt ataatgtcca taatagtatt
     7561 aatttctctg tcataatctc caggttttat aatgtctact tttatgtctg ttattaactc
     7621 ttctctttct tttatttcat ctatacttga taaatctatt gtaagtacat ctttctttat
     7681 agaagttttt gaaccgaaat taacttcatt catatgaaac ggttttataa caagtcttct
     7741 cattattttt tcttccataa tatccacctt tgttcttaaa acccctctcc taaccgtgta
     7801 ggagaagggt tctatatttt caaatataaa ttacatttta aacgtgagct ttatattcgt
     7861 atggtaatgg aactatctta ccagcagatg gtattgcaac taattgctct aatgtatctc
     7921 ttaatatatg tgtttgcatt tctatattat gtggttcacc agcattagca cccattggaa
     7981 ctaatggagc aactgctcta ggagttccgt tttgtctaac tactggagga agagctgcta
     8041 ttattattgt aggtattcca gcttcctcta ttgctctctg cacgatcacg gcagttctat
     8101 ggcaagtacc tcagccagct gtcataacta caccgtctac tccctcttcc ttaagtttag
     8161 cagcgatagc aggaccagtt tcttcagtga agacatgttg gtttcctcca ccacccatga
     8221 atgcatagtg cataggagct actcctttga taaatccttc tgcagctaat tcatgtaatc
     8281 tatctatagg gaacatacag tttatatctt tgtttacatc tccattgtca tatccaccat
     8341 gtgataccat catttcatca actgtagctg tattaggtat agctctaaat gtagtatctc
     8401 ctgctagatt aaatctcttg tcagatttta aatgaacacc agctgctgta gctaaagcta
     8461 tagtcatatc ttttaattct ttagttacag gagtccaaac tggaggaggt gttattggaa
     8521 cgaatatttc agattgaagt ccttgtactg ttgtaaggct catatatttc ctctcccttc
     8581 tattttcaaa cgattattta ttatttttct tcttgttttg attgcatttc tgcttgtttt
     8641 tctttttctc tcctaatatt ttctacatac tcttgattag gctctggact taatacctca
     8701 ggatagctta gcatgaatcc aacttcttga cctatcttaa gttcgtagtc agttataagc
     8761 attctattag gtattttaaa ttgtccaagt ctacctttta ggtctatagt cactccaccg
     8821 cctttgatgt caactataat accttcataa aaagtctctg atgagatata ttttaaccta
     8881 tccattataa ttctacctct ctatactgtt ttaaacttgg atctaaattt atgttattgt
     8941 ctaaatctta gttagtatct aaattttagt tttcgtcttt ttcgtatatt tctcttctct
     9001 tcttactcat tggtagagat tgctcattct cttctaatac tattttttct cctgtaactt
     9061 tttctatagc ttctatgtta tttaatttaa catttggatt ccattttctt tcaggagctt
     9121 taacttctac accttctata gcatttttaa gcatagccat tattctaaca gcatcttctg
     9181 gagctaaagt gttgttagat aatatttcat tctctatacc ttgcttagac ttattgttgt
     9241 ctaccatgtg agtcatgtat ttattaccaa caactagagc accttgaaca gctgagaaac
     9301 ttacaccaac tactggtata cctctcatac ctatttgctc tatgtgagat gcgaaatcta
     9361 tatggttgtt tccgaaacct tcagtagtta ctacagctcc atcaacttcc atagcttcaa
     9421 ctaacatacc taatctctta gatacataga atttctcagc atttacttgt ggagaaccaa
     9481 caaatacaac acctactaaa tctatttctt cgtcttccat agctcttatt actaatggct
     9541 ctctccagta atgtcttgac atttcttttg atgcaggtcc tatacaagtt aatgcatgga
     9601 taccaccatc taatacttca agtggagata atacaactgg catgtttcct aagtcaacgt
     9661 ttggttgagc tcctaatgta ccaactggct caactggtaa tattaggtta tcatgcattg
     9721 caccttgtcc cattatttct tttataacaa caactttctt tttaccttct cttctgtatt
     9781 gctctattac ttcttcatca actactaaag agttgtcaac tttctttaat gcttctctta
     9841 tttcttgagt tacatagtca aatgcacggt gagcagctaa aggtcctggt ctttccatgt
     9901 tagttcctgc ttttattgtt acttgacctt tgatgaatat ttcacctttg tcagcagcac
     9961 ctggtctacc ccacattata gtagtattta actcaccttc tgaagaacca aattcaccta
    10021 tttgaactcc atcttcatct gtaccagtta ataccattac agctccatct ataactctag
    10081 ttatacctga acctaattcg ccttcttctt tagtagcgat tggttgtata tctaatacag
    10141 cttcactgta agtttcatat ttatcaggag ttattatttc taacttcata tctacaacta
    10201 actcttgagt ttcattagct tctttacata tttcttctgc gtttctgatg tataaagtag
    10261 ttccttctat tttagtttca tcagcaaatt caactttatc tattttaaag tgttttttag
    10321 ttaagcttct taaaagtttc ttttcttcaa cttttggagc tacttctgct gctgcacttg
    10381 ccactggagc agcaacgttt gctactggag cagcaactcc tgcttgacca gctactgata
    10441 aaggtatctc taagcttatg ttcttacctt cacctatgtg tattttaact gtttcacctg
    10501 caactcctgt gcttactgga actactgctg cttctgatac tggagctgct tcttctactg
    10561 tttcttctac tacttcttct ttagcctctc ctgctttgta tccttctacg ttatctgtag
    10621 tcattggaga aagtgcatct aaagtttctt ttaacttagc tcctagtact tgacctatag
    10681 ttaatccatt ttctggtatt gttaataatc cagaatcctc taagtctgca aatattgctg
    10741 gatcttctaa gttttctggc gctataattg ttcccgcttc aaatctacaa caacaaactg
    10801 ctgggtcatt tgcatgggct tgagctgttt ctaaagttat tgacatagta taaaatacct
    10861 ccttacatta ttttcttatt tattatttta aatctcaatt cctcaacagg taacccctta
    10921 actgagaaat taagtaaatt aaaacctaca taatttgtta tgattaatat tatttttttc
    10981 tcacttaaag tcactttata ttataagcaa ttcctatgcc aacttattaa caaaaagatt
    11041 ttttctataa tagattcttc atctatcgct atttttagcc aaatattata taaatattta
    11101 tttaaaatat gttatttttt gtatttgtaa acattttctc aaacaaaaaa agtgtcaatt
    11161 aatcaacact ttttcatttt ttttaacaca tctatataca caacacttat acaagtgttg
    11221 gctttactag gttttaaatt aaagtttatc attttgtcaa aatttagtca tgtgtcatat
    11281 tttagacaca tctattttgt attggtctat cttataatac aaagttgttc tgggtatatt
    11341 taatatctta gctgctttag ctttatttcc attagacatt ttaagtgcct tggttatatt
    11401 ctttatttca attttttgag ttgccttcgt taaatctaaa ggatactctt cttcttcagt
    11461 actattattt gtagaatcca tcatataact tggtacatca tccacatcta ttttagaatt
    11521 ttgtgacaat acaacaatat tttcaatcgt attttttaat tctctaatat tacctttcca
    11581 tctataattc tgaaatatat ctattacatc tttgctaatt gtaagaacag gcttattatt
    11641 ttgtttacat atctcctcta aaaagctatg aaccaataat cctatgtctt cttttctctc
    11701 tctaagtgga ggaatcttta tttcaacaac atttaatcta tagtataaat cttctctaaa
    11761 tttttctgcc tttaccattt tactcaaatc tttattggta gctgatatta ttctaggatt
    11821 tatttttatt gtggtatctc caccaactct tcttatttct ttttcctgta atactctaag
    11881 caactttgct tgcatactaa gaggtaaatc ggcaatttca tctaaaaata cagttccatc
    11941 ttttgcaagt tcaaatatac ctattcgacc ctttttactt gctcctgtaa atgcacctga
    12001 ttcataccca aaaaactcac tttcaaataa ctcatttggt atggcactac agttaacagg
    12061 tataaattgc ccttttctct cactataatc atgaatagct cttgcaaata cttctttacc
    12121 tgtaccactt tcgccccaaa taaatatact actatttgtt ctagccactt gttttgcaat
    12181 cgctttcgat ttttccaatt tataactttt acctaaaatc ttatcaaaac tacctttaga
    12241 taaatttttg acttcgttct ttagatattt taatgtatca tttacttttt caagttcaag
    12301 agctaatatc ttagcttctg taacatcaac ttctgtacat acaacaccga taaattcttc
    12361 tttataaaat ataggatttg catgaactaa tgcatacata ttttcttttt tatctgtaaa
    12421 atacaagtca ctcattccaa ctttactatt tagtactttt tctgaaatag tattttccaa
    12481 aaattcattc atcggtcgac caactatatc ttcagacttt atatcatacc tttcctccat
    12541 aaacttattc cacaagataa caacaccttc gttatttata gcacaaattc cttctttaat
    12601 ttgacctata atatacttca aagttaatcc ataatcttct aaatgcatat atagatagtc
    12661 cctaatgtgc tcttgtttta gaactccaat aattttatta tctctaagaa caggaagaat
    12721 ccctatattt tttaatatca ttatatctct acattcatct aaggttaaac cttcgttgac
    12781 atatattaca tccttcttca ttataagttt tactggttga ccttcatact ttttatgcat
    12841 ctcataaaga ttatgtatat ccgtcatgga tataatgcct tttaattggt cagatgaatc
    12901 tattaccatt agagtttttg tgttgctttt tatcatttct tttattgcat cttcaattct
    12961 tgtgtcttcg tctatagttg taaattttgt atccattacc tcttctactt tttttacttc
    13021 tggtatcgaa aacataaagt ccccccttta tagtagtacc tcatcaaaac ttatttatat
    13081 atatttattc tagcatatta taataattat ttattaaata attattatta aaatttatta
    13141 agtaattagc atttaaattt atataatcac tttaaaattt ataattaaat ttatacaaat
    13201 gaaatcaaat gaattatacc cttagtatat tattttttca atactatttt caccttcaaa
    13261 acatttttct attcatcaaa caattaatga atgcctgtat ccaataataa atttaagaat
    13321 ataattaaaa tagatatttt taaacaaact atatttgcat attatattta cataaaaaag
    13381 ccccaaaatg acttataaat caatttgaga ctttttattt taaacttaat aataatctag
    13441 attaatttct ttttatttta cattgatacg ctaatccaca aattgcaatg acactaataa
    13501 atacatatga cattagctga gtttcatcac ctgtttttgg tgattttatt attgtatcat
    13561 ctcttgatag ttctggagtt ttttccactg tatcacttac tgatggtact ggtggattta
    13621 acactgtatc ctctgttggt ggcactggtg gatttagcac tgcatcctcc attggtggca
    13681 ctggtggatt taacactgca tcctccgttg gtggtactgg tggatttatt attgtatcat
    13741 ccattggtgg tactggtgga tttattactg tatcatctat tggtggtgat ggttttggct
    13801 tatgtccatt tgtatcatct gttggtggca ccggtggatt tacaacatca tcatctattg
    13861 gtggcactgg tggatttaca acatcatcat catctgttgg taaacctata ttaaagttaa
    13921 cttcttgacc attctttttc tctattgtat aacttaataa attttgcttg ctagatggta
    13981 atgaagatga atggtctttt tgtcctaaat caagcactgc cttataatat tgaatagctt
    14041 ttggaaaaat ataatcataa gatacagcag aaatattagc tttggcatct ggttttccaa
    14101 cactcttaag tttaaatttc tgttgcgttg aaatttctac ttcgcctgta cctattatat
    14161 taccatctcc atcataagca gttactccat ctggtagttt taactttact acaccactat
    14221 aacctactaa ggctacagct tctgtttcat aagtaccatc ttcatttttt tcaaagttaa
    14281 tcttagttaa accattactc aaactaggtt ttcctgtatt atttggcttt aactcttcac
    14341 gacctgcttt taacaatgct tctaaataag cttttatatt tatcgctact tctttcttct
    14401 tctgatactc agctctttcc tcttcagttt ttgctctttc tataagttta tcacaaaggt
    14461 ttatagaacc ttgatactgc ttaagtcttt cttgttcatc catttgtcca agaataatcc
    14521 aaattgcact ttgagtagct gagtaagtca tcaattcatt ttcttctcca cctaaattaa
    14581 attgttgctt atatccaaat ccatcaaatt cagaacctgc atatagtata gatttaactg
    14641 cttcttcatt ttggttttct tgaccattaa aatcttctgc tggtaaatat ggactctttc
    14701 cattactact tggtggtctt aaatgattat tgtaacaaaa tgcagtttgc tctccatctt
    14761 caccttctat tacatatttg tcgtcttttg agcttgctcc tacaagaccc tttattacat
    14821 agtcaaaagt taaagtcttt gtaatatcat caaatcttaa atcatgataa ggtctatctg
    14881 aaccatctat ttcttttagt aaacaagaat tttttacttt tgcttttttg tcataccata
    14941 agctaataaa tgagtcttct gaagtaaaaa cttggttaat ttctgattgt tcatctgcct
    15001 ttacatcttc ttcatcttcc caaaagttat atactatttt atttatttga gataaagtca
    15061 tatcaagaat tttatcaata tcttgtttta aactcatttc ctctataact atttcttctt
    15121 ccaatggttt ttcttcttct ggagtttgct catctaatgg tttctcccca tctggcatct
    15181 gaccatctga tggtttctct acatctggcg tctgactatc tgatgtcttc tctccatctg
    15241 gcatctgacc atctgatggt ttctccccat ctggtatctg accatctgat ggtttctctc
    15301 catctggtat ctgaccatct gatggtttct ccccatctgg tatctgacca tctgatggtt
    15361 tctccccatc tggtacctga ccgtctgatg gtttctcccc atctggtact tgactgtctg
    15421 atggtttctc cccatctggt acctgaccgt ctgatggttt ctctacatct ggtacttgac
    15481 tgtctgatgg tttctcccca tctggtacct gaccgtctga tggtttctct acatctgatg
    15541 tctgaccatt tgattgttct tctccattaa gtattgtatc attgctagtc acttcgtcag
    15601 cataagatac tattggtgta aatgcagtaa ataccatact aaaagcaatt actaaactga
    15661 ttatacttga ttttttaatt tttgttttca aaattctcct gatactaaaa acatatattg
    15721 tattcactta atataattaa aattattaaa tattatatga atcttattca ataatacatc
    15781 tttagtgtgt tcaattaggg tcgttactcc taaccagttc tcctatgaac ttcttaatat
    15841 ttctattaag cacagactat atcattacct aaccataaat taggtactcc ccatttcccc
    15901 acacttgtag gtacgagatt tctctctagt cgttgaagtt tcttcttttc gaagcttacc
    15961 tgctgattat ccattttcaa ggcacttagg atttaacctt atgctatcta actaattttt
    16021 tctactttcg taacctcaag tgcttattaa atgcacactc tatcacactt atccttattt
    16081 catgattatg ttgtggttta gttagcttta ggaacttcca gcaattaaag gagttttggg
    16141 cagatatctg ccactctaca ctcgttatga atgcagggag catttcaaaa atatatttat
    16201 atctatcttc tattaattac ttatttatgt atttatttta tatatttttg acaattaaaa
    16261 gttactccta tttatattta tagcaggttg cactactaac tccatatatc ttttaagtgc
    16321 ccaggtttaa gatatacttc acagtttcta taaataggtt tttaattttt cttttttaac
    16381 tttttaagtg cactttttta acaactcaat aaaatataaa ttagtatcct agatacttat
    16441 ctaataaaag acaaaaatta gtttttataa taaaaaagat actatagagt atcttcaaat
    16501 atcacaaaaa ccttttactc tatcggatag ttgacttaat ataatatgca tattaataca
    16561 aaccacatac ttgagtatca ttatttttgt ccaatattaa ttgtaatagc tattgttatc
    16621 attatacaat atctagcata ttttgtctat tttttccatt tattttacaa tatatatatt
    16681 gccctcaaaa tacattaaaa aacatcctta gaagtaactt ttaagtttta cttctaaaga
    16741 tgtctaactt ctatttatct attattttat ttttaatctt acgtcacctt ttattcttct
    16801 tattaatggg tgattaactg ttctcattac atggtcagta atatgatata cacctaattt
    16861 taattttggt gcagaaccca ttactgtgtt actacagtca gtacagtttc ctattaatat
    16921 aacttctgct ccagctttct taaattcaat acatttttga gcttgtcctg gacagtgtcc
    16981 tggattttca cattttaatg cacctttaat ttcttgagct tgtttacatt tttgaactga
    17041 tactatatca gtaactccca ttttagttgc tatatctctc attctttctt cattaggtcc
    17101 acatgcacaa actaaaagac ccatttttct cttttcatta acaaatggca tagtaactat
    17161 tataccacca ctagttttag ttattggagc atctaaagta gtagctttac cagtgaaagg
    17221 tcctcctagg attatttcac catattcacc ttttattcca ccagctcttt caattaattc
    17281 tccgacagtt gttccaattg gcacatcttc aaacactata gattcttttc cactgtttaa
    17341 ttgaccaact acagttatat ttttagatat aactggtctt ttttgctcaa cagcctctac
    17401 tattctagtt agtgtttcta cgtttattac tactgcatta gcctctgaag gtaattgagt
    17461 tggctcaagt aattttccta gaacatctct tactattgct ctctcttctc ccattgggta
    17521 catatcaact agttctgcaa cttctatgtt gtctcctggc tttattactt ttttgaaagc
    17581 ttctattgct tttggatgct tactttttat tgctagcata ccttttccag cattagtaac
    17641 ttccatagca tattttatac cttgataaac tatttctggt ctttcttcta tttcttttat
    17701 attatgagct aataaaggtt cacattcagc tgcatttgct aatattgttc caccatttaa
    17761 atctatgttt aattttacat gagtagggaa tcctgctcca cccattccta ctactccagc
    17821 ttctttaatt aagtcaagta taccttctcc ttttaatggt tcaaaagtat cttcttgtac
    17881 ttcatcagct tcaattacta tcgcttggtc atttatttca cttatttttc cactaacact
    17941 ggcataaata tttgccccta atccagttgg ttctgcgatt agagttcctt tttttactac
    18001 atctccaaca cttactactg gcttatctgg accaccaacg tgttgtttta ataaaataga
    18061 atatagtttg ttcaactagt acgccccctt aagtatatta atttttttat aagctgttca
    18121 aataatgtta atgctatttt tctattataa ggtcttaaca tattgtttat ttctatagaa
    18181 catatcgctt attaacaaag caatttctat gccaactttt aaacaaactt ataccctttg
    18241 gaaatactgt cttacagcat tcattaattc ttctaaattt ttaaacccat caaaaaaaag
    18301 tcaattatta gacacttttt taatcaattt aatctataat tattgatatt gcatacatgt
    18361 ataaaaagtg tcaaaaaata gacaccgtct ttttatcgac acttttctaa catatactat
    18421 ataatttatc acaactttac ttaaaatata catttattac ttattaattc ttagtttttt
    18481 gcactccatt ggaatcaact acataattat ctttatacaa caaatcagat attttgacta
    18541 gactgtatcc atcttttttt agtcgactta ttatagtatc caaataatta tctacatcat
    18601 ttatattagc atggaataaa actattgaac caggttgaga ttcttttatt actttttcaa
    18661 ttacatgatt tggtccaagc tccttccagt ctatagaatc tacatcccac ttaattactt
    18721 tataacctaa atcactacaa atgtccatag ctttattgtt tacgtcccca aaaggaggtc
    18781 taaataaatt agtccttttt cctgttatat tatatatttt ttctgatgta gtttctatct
    18841 cttttgttat gtcttctttt gatatttcct ttaaattggc atgagtattt gaatgatttc
    18901 caatttcatg tcctttttca tctatagctt ttacaatttc ttcattatca tccacccaac
    18961 taccaactaa aaagaaggtc gcttttacat tatgtttatc taaaattttt aaaatatcat
    19021 ccatattatc agttccccat gctacatcaa aactcaaagc tatttttttc tcatttgtat
    19081 caactttata tataggcatt tttgaattgt cagatttaga acatatgtat tttattccat
    19141 aaacaaaaac aaatattaac actaataata atgaaaaaaa taaaacacta tatatcaaag
    19201 ctttagtcct tttaacttct cttttcatac tattccccct ttgaaataat ttcttctata
    19261 tttaaaattt attttttttc agctcaaaaa agtactgtaa tatttaattt ataagacaat
    19321 aactaaaaaa ataaaaccta tattgaccta attaaactct ctaaaatact catttattta
    19381 atttttttat attttttaca tttttacctt tatttttctg tatatattat ttttattttg
    19441 gagaaattag tattaacatc acataaataa aagtgttgtt agacatcata aactaattat
    19501 ttgaggagga aatttactat gtcaaattca aacagaacag tagttccaga agcaaaagct
    19561 gctttaaacc aaatgaaatt agaaatagct aacgaaatag gtttatctaa ctatgaaaac
    19621 atagacaaag gtaacttaac agctagagaa aatggatatg ttggtggata tatgactaag
    19681 aaattagttg aaatggctga aagacaaatg gctggaaaat aaatagtaaa ttttgacacc
    19741 tgggtatcaa cagggctgct aattagcagc cctgtttttc tatatttatt tataaaattg
    19801 tttttatatg aattattaaa gattaataat acaatacaaa ttgttctttt aattttgtac
    19861 aaattagttt aatatattat atatagaaat agtttgacgg aggatgatat ttatgtttga
    19921 aaactcgtct gaagaattag cctatcacaa acttttaatt ttatatatat tagaaaaaat
    19981 taaaatggat ttaactaatt ctcaaataac tcaagtagta ttagagactg agatgatgaa
    20041 ttatttttca ttacaacagc ttttatctca gcttatggaa tctaagtttt tgactacata
    20101 taaagactct gacagagaat attatgctct tactcaaaga ggcgtagaaa gtctagaata
    20161 cttctttaat cgaataccta ctagtgttac tgaaaaaata gacaagtata tagattctaa
    20221 caaagaaaat ctactagcag atactcaagt aaagtctagt tttgtaaaac aaagtgataa
    20281 tgaatttatt gtcaacctta gagtcataga aaatcagtct aacttaatag atttaaatct
    20341 aaatgtttca tcagagaaac aagcaaaact tatttgcaat aactggaaaa ataatgcatc
    20401 ttatatgtat gccgaagtta tcgatttact tataagagac atacattaaa gcctacaaac
    20461 aaattatagt tgtaggctct tttcctacct tgatttcttt tattaatttg ttatttgcag
    20521 tttcataaac ttttactgaa ttttcttgtg tatctgatac aaatagtaac ttttcatctt
    20581 tagatatttc taatccttgg ggaatcccat ttatttcaat atttccaatg tatctactcg
    20641 ttgtataatc taaaattctt acattattat aacccaaatc agcaacataa acttttttgc
    20701 cactataatt aaatcttatt tctactggta ataaaaattc atataatacc ttttttatat
    20761 ccatgcttac ttcatctatt attataagct ttccatcaag tgttgatata tacatttctt
    20821 tcttttgttt atcaagttct atatgccaag ctctaaagtc catatttatt ttcttttgta
    20881 tatttttatt aattgtatct atacatacta tcgagtttat acacggtaca tataactttt
    20941 tgctttctct atcaaagtca aatccatgtg gcatattatc aactccaata attcctattg
    21001 gatttaatgt gtttttatct agtacatata tactattaga atcttcattt gccacaaaca
    21061 attcattatc gctaagtaca acttgactaa gacttcctcc tatagagaca gtatcaatta
    21121 ttttatcatt acttaaatct aagacataga gtatcccatt acttgaacta ggtatgtata
    21181 ttaaattttt ttctttttct atgcaaaaat ggtgtggata tatattatct tctaatacta
    21241 tttctttttc tagttcaagt gtagaataat caactatgct aatactcttt gataagtagt
    21301 tagaaatata gattttcata taacccctcc tctctacaat acatatacta caataatata
    21361 ttatttcatt agcttgtatt atgctttata gttgcattat tacgcatata tttggtatta
    21421 ttattaatgt taaaaaaaga aataatattt aatggaggtc tttttaatga aagtaacatt
    21481 taatccaagt ggtgtatgtt gtagagaaat gatttttgaa gttgatgaaa ataatgtgat
    21541 tgttgatgct gaatttatag gaggatgtaa tggtaattta tcaggactta gaagcttaat
    21601 aattggccaa aatgctcttg aagttgctga taaattaaat ggtattgact gtggtggaaa
    21661 aggtacttct tgcccagacc aattatctaa agctatacgt caatctatat aattacttat
    21721 ataaacatca gtaaaattat taaaaactta ttttatataa aaagagttgt ccatttttta
    21781 gacaactctt ttttatattt ttatttgtat acttatttta taaaattata atttctttac
    21841 taaagttctc actgtaccaa tcatatataa tgaacctgca cttattataa tatcatcctc
    21901 acttgatgtt tctaatgtat aatttactgc atcctctatc tcatgctttg atgttacatc
    21961 atctacatat tttaatactt tttctcttaa tatatctgaa tttatggctc ttgggttact
    22021 tggtgttgtt gttattacct tattaaaatg tggcaacaat atctctaaaa cactatcaat
    22081 atctttatct tctaacatac ctattaataa ggttaatttt ctacctttaa aattcttatc
    22141 aagtgctttt gccaaagatt ttgctccatc ttcattatgt gcaccatcta ttataaaaat
    22201 tggattttct tttatctttt ctattcttcc tggccattta gtatttataa gtccttttct
    22261 tatagattct tcatttatat ttgctaattt atttatgtct tttagatatt ttattacact
    22321 aattgccaag atagaattgt ttatttgatg ttcgcctatc aattttattt caaggtctct
    22381 ataagtttct ttcattacag tacaatcgta tatttgagaa tttatatctg atttttttat
    22441 gtttatatca tcaaaatcaa cttctatata tttagctttt ttctctttac aaactgactt
    22501 tataacatcc tttgcttcat cagtctggtc atatactagt actactccat tttcctttat
    22561 tattccagcc ttttcgtacg ctattttttc tattgtatct ccaagtatac ctgtatggtc
    22621 caaacttata gatactatca cacttacaag tgattttgtt attatatttg tagcatcata
    22681 tctgccacct aaaccaactt ctaatgccac aaagtctacc ttttgttctg aatagtaata
    22741 aaatgccatt gcagtaacca cttcaaattc tgttggatat gcatagcctt cttttaccat
    22801 aatctctatt ttttctttta ttaactcaat tattctagca acatcatcct gtggtatatt
    22861 ttgtccattt actcttatac gctcagtaaa agtttctaaa tatggagatg tatataaacc
    22921 aactttatat ccacactctc ttagtatatt agaaacaaaa gaacacacag aaccttttcc
    22981 attagttcca gctacatgta ttatattcaa agtttcttgt ggatttccta ataattctaa
    23041 taactttccg atattttcta atcctaatct tataccgaat ttattagttt gtgatatgta
    23101 ctctaatgct tcttcatatt tcattatcta actccccctg tattggcatt ttctcttatg
    23161 ctatctaatt atagtatatt ttttactttt aatctaccga caaagaatac atataattta
    23221 ataccttcta cattaaattt agctacaaat ctttatttat aagtttttat atctttccac
    23281 taattcagtc agtgtatata ttgaaactaa gtcatatttt gagatgtcca tataattaaa
    23341 ctttatgtca aatctatgct ctagcttttt caacagatta aaacaattat cataaaccaa
    23401 gcctatctcc ttattaaaaa ggctaccctt aaagagtttt tcattattct cttcaatatc
    23461 taagcaatcc ctaacaacgt cagcaacttt cataaaaaga gcattttctt tgtcatacaa
    23521 atccaattta aagtttacaa ttctactaca ctcatcaaaa tcacaactat cccaatgatt
    23581 tctagttgct aatgattcaa gcttatcatt taaatcagat attgttatgc ctggtttttc
    23641 tgataatatc ttagctattt taccagtaag ctttgctgat aaataactat tacattttgg
    23701 tggtaatcta taggaattat ttatatcaca acttatatat gaattgctat ccataacaca
    23761 ttgaacatca tattttttgt tgtaccaaaa tgaatcatct ccatctaaag taaatcctct
    23821 tacacctata acattgttaa acatagctgg ataacttaag tcaaaatcat tagcgagtga
    23881 acatactatt atttttcctt ttctaaacaa ttcataacaa acttcaaata agcccttaac
    23941 actttctact cctatgactg ataaacttaa attaattaat cttatgttag tgtctaaaag
    24001 gtatcttaat gcttcttcaa gaacttttat atttgtaata ccatcttttc tcaaaatttt
    24061 tattacaaat aactctacat cttcatactc tttctttatt attgatgcac aagcagttcc
    24121 atgaccatct tcatcatcaa atttatctga tataaagata taatcatgca tacattcaaa
    24181 agcaattcct ccaactaaat tatcttttaa gtaatcatgt tctttgtcta ttcctgtatc
    24241 taatactgca accttaactt tattattcat atcacatata ttctccatta caaaagtttt
    24301 taatatatct atgttaatag ttcatcttaa actttgattt aagttgcaca atttatcttt
    24361 taaatgctat atttcttgct aaaaacataa aataagtaca ccatatattt aatttatatt
    24421 tattatatca attattatca ttaaatggtt aaatgttaag ataaaatttt tagatttata
    24481 tcacaattta gaattatttg taaaaaagga gattatcttt ttattagaca atccccttgt
    24541 atattttatt aatatttatc tatgattaag catcaatttt attttatact ttttgatttt
    24601 aatactatac atctaaatct tatttagggg gaacaattat ttatatgata taaaaatgct
    24661 aatttgaatg aacttgtctt ataatcagtt ttagaaaata caccattcta caaagtatga
    24721 atcaaaaggt gaaaaaatac taaaaataat aaatcaacat caattttaat caatatatga
    24781 aaaacttata ccaagtatgc ataaaaacta atataaatat tattttaaca actaatactt
    24841 acacctttat atattatatc atatttcaat aaataaattg cataaaagga aatcttttca
    24901 tagaattaaa ctatttatta attcattact ataggttcaa taaactataa gatgtcgctt
    24961 taatatttat attgtactcc attaaatatt aatataatta attaaagtat gcatagctaa
    25021 atgaaacaaa tatctataga gttttataaa tagtcattat tttaaaaagg taatcatatt
    25081 ctaaaaatac atataataca tataaaaatc aataatagta tattgataat caagctacta
    25141 attaataatc atgctattat aatggaaact ctacatatac atattaaacc atattaaaag
    25201 tctataaact gctattttgc ataataaaac tgtcttaata taaataacat tttatatatt
    25261 aagacagttt caatcaatag ccctgtgatg acattaaatc ttttttacga tattttcaat
    25321 taccttttta aaattaatac attatatcac ataacaagct tgttaatgct acttttaaat
    25381 ctttaagtct atacttactt ataggtataa attgttcatt aatagtaatc gtattatccc
    25441 taagatcttc tattcttctt aaattaacaa taaaacttgt atgacatcta aaaaagccat
    25501 tttcacacag taatttttct gcttgtttca tgctcatatt agctttataa tctctaccta
    25561 ttgtatgtac aactaaatct ctctttacag tttcaacata taaaatagaa tctatcagta
    25621 ttctattaaa tcctttttta ctatttaaaa ctatataacg ctccttcttt ctttgaaggt
    25681 tatcaataca aagatttaca cccattgcaa agttactata ctctataggc tttactaaat
    25741 atctataagc acgaacttca taaccttggg gggcatactc tgaaaaagcc gttgtaaata
    25801 taatttctac tttttcatca aactttctta tttttttagc cacctcaatt ccattgatat
    25861 ctttcatttg gatatctaaa aatataatat caattttttc tgggtatttg gatattaaat
    25921 cttctccaca ggaaaattcc agtatttgat aatttagaca tctttcagac aaaagttttt
    25981 ctgtaaactc ttttagtatg cttctttgta ttttttcgtc atcacatata actaccctga
    26041 acataatatc acctccaaat ctaaaatatc atttagttta ctttatttca atttccaaac
    26101 tgtactcact agctttcaaa tttaaatttc tttataaatt taaattgtcg attaaactac
    26161 ttatagaaat tctctttaat atttaaactt aaattacgat aaattcctat acttttctag
    26221 atatattatg taaaaaaata
//
LOCUS       DAEPKC010000052        26022 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.052, whole genome shotgun sequence.
ACCESSION   DAEPKC010000052 DAEPKC010000000
VERSION     DAEPKC010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 26022)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26022)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26022
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.052"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(179..676)
                     /locus_tag="KR294_002202"
     CDS             complement(179..676)
                     /locus_tag="KR294_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HBH0240279.1"
                     /translation="MNYEIVEINEKIVIGISKETTNKDGQAINDIGELWKKFMGKGIY
                     NAIKGKKNDKTIGLYTDYQGDFTSPYSFVACCEVNSNSDKEKNLEELNTNNTVGESII
                     SKVIPAGKYAKFVIVGGQKEVGDFWFKFWQMDFDRTYISDFEEYQCNTFDTKKQEIHI
                     YIGIK"
     gene            complement(851..1762)
                     /locus_tag="KR294_002203"
     CDS             complement(851..1762)
                     /locus_tag="KR294_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YafY family transcriptional regulator"
                     /protein_id="HBH0240280.1"
                     /translation="MKINRLTEIIVILLNKKLVTAKELADRFEVSTRTIYRDIETLSM
                     SGVPVYMTKGKGGGISLIEEYSIDKAILSKKDKESLIVALKTLQATKYPEINSVVNKI
                     GSIFGEQNFSNWIEIDFTEWGSNFNEDDKFTKIKEAILRRNTINFNYVNSLSSQTNRT
                     VEPLKLMYKSKTWYLYGFCKLKDDFRIFRISRIRNLSIKDEVFSRKIIEEVCLNDSKV
                     IKENTITLKLRFKEKMLFRVFDDFNKDLITKNEDDTYDVITEFPIGEWIYGYILSFGD
                     NVEVLEPKDVRDNVITRLRELSKIYSL"
     gene            2687..3538
                     /locus_tag="KR294_002204"
     CDS             2687..3538
                     /locus_tag="KR294_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3100 domain-containing protein"
                     /protein_id="HBH0240281.1"
                     /translation="MEINKKHFIQVFLTCLILVVICEFIGQRTIAIGKASIVLFPMLY
                     AVIIGLIITPDLLGKKIKALKKVVGEKEINIAGEVVGIALVMLGIKYGTTVGPNIDKI
                     IQAGPAFIAQEFGHILAPIVALPLALMFGMKREAVGATASISREPSLGVISEKYGINS
                     PEGSGVLGTYLMGTVLGTIYFSVLGSISIYSGLHPYALGMACGVGSGSMMTAAAGSLS
                     TMVPPEMADTILAYAATSNMMSSITGIIFLVFVSLPFTNFMYKILEPKFSRNKKTKEI
                     KSTEGEC"
     gene            3542..4012
                     /locus_tag="KR294_002205"
     CDS             3542..4012
                     /locus_tag="KR294_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240282.1"
                     /translation="MFANLNLKKSSYQLLVMSVIGVIILIGQRISVGTSIVTALPGMV
                     MLILAAMAAMIIKDLFPKSIFPAFGFATIIGLLLSMPYSPTSEVFLTNTNNINFMAIT
                     TPLLAFAGISVGNKIEALKEMSWKIVIISLIVFTTIFFACASIAHIVLSIQGKI"
     gene            4025..5335
                     /locus_tag="KR294_002206"
     CDS             4025..5335
                     /locus_tag="KR294_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH0240283.1"
                     /translation="MNKEQLKSLVIKTIDENREKILKIGQGIYKNPEYGYKEFKTTEA
                     VSNFFEQELNLSVEKNIAVTGCKADANSSKKGPHISILGELDGISCKEHKDANEIGAS
                     HTCGHNIQIAGMLGAAVGLVKSGVLEHLDGKVSFMATPAEEFIELEYREQLKKEGKIT
                     YFGGKQELIKRGYFDDIDISMMFHASDLGEDKALVGPESNGFVGKKVKFIGKESHAGS
                     APHDGINALNAAMLAINNVNALRETFKESERVRFHPIITKGGDIVNVVPADVHMESYV
                     RARTINGMIDANERINKALMAGGMAVGADVEITEIPGYLPILRYKSLDNLFKNNLEDL
                     GLKGKVIDGGDFTGSFDFGDVSHIMPTLHPMIGGVKGALHTRDFEIVDEDLAYIIPAK
                     AMALTVVDLLFDNAKDAKDILDTFTPVMTKEEYLTFLEKHDKTL"
     gene            5547..6293
                     /locus_tag="KR294_002207"
     CDS             5547..6293
                     /locus_tag="KR294_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBH0240284.1"
                     /translation="MFNAGNRIINTWLYPIQDDFVLIDTGYENGFKHFKKRISKFNIK
                     IKDIRYIFLTHAHDDHVGFLNQILDESPNTKIVMHDKALEILYKGQNSFIGGCTSRTA
                     FLFCQIMKLFGKGEHSFSPLKQEFEKRCILVSDNNRKEIEKELNGKIIDTPGHTADSI
                     SLLIDDGVLFCGDSAMNGFPSTHKITIFAESKLEFIQSWRTIINTKPKMIYPGHGKPF
                     EYSKLEQNLIYVNKINLYPLHNSKDIHRFL"
     gene            6654..8195
                     /locus_tag="KR294_002208"
     CDS             6654..8195
                     /locus_tag="KR294_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbgT family transporter"
                     /protein_id="HBH0240285.1"
                     /translation="MNDNVVKKKNFFDRTLNRIETVGNKLPDPVTIFLGLCVLLLILS
                     SLVGSMGISVVHPGTGETITAVNLLTVEQLQILLGNIVSNFQGFAPLGLVLVTMIGAG
                     VCDKTGLMTATIKASVSKIPETRVTLVVMTIGMLANIASDAGTILFPPLAALVYLGVG
                     RHPLIGLFSGYAAVCLGFAANIMISVNDILAASFTVPAAQMIDSGFQANATMNLFFMI
                     ASTFVLILLATWVTEKIVAPRFGKYEGNAELDVDGSLSDVEKKGLKKAGISILIYVAI
                     IVALSVIGKKPFLADPETGDLLSNNAPLMKGMVPIIALAFFIPGVVYGKTIGKIKKDK
                     DVVSIMASAMSDMGGYIILAFAASQFLQLFTNSNLGLILAVKGGEFLKSAGINGPLLL
                     IGFIILSCFINLFIGSASAKWAILAPIFVPMFMMVGYNPALTQMAYRIGDCITNPLSP
                     LFPYFPIILAFTRKYDKDAGMGTVIANMIPYSISFLIVWTILLILFMVFNIPLGPGIL
                     PSYSM"
     gene            8230..9336
                     /locus_tag="KR294_002209"
     CDS             8230..9336
                     /locus_tag="KR294_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HBH0240286.1"
                     /translation="MLDKNRLINNFMDMVRIDSPSNQELEMSKWLVNYLKERNIDAII
                     DDAGEKYGGNTGNVIAYIKGEEGSRPLCLCAHMDQVQPCLGVKPILDGNVVRSDGTTT
                     LGADDKAGIAAILEALEHVITEKIPHRDIYLCFTICEEAGMYGVKNFNPDNLPCKDMV
                     ILDSGGAIGSIAYKAPAQQSIKISFHGKKAHAGIEPEKGLNAILVASHAISNMHIGRI
                     DSLTTSNIGKIEGGGATNIVTDKVTLTAEIRSHIPETLEYELNHMEKCCKDAASKFNT
                     TYTFEHNMSYPSFELSRDSHVFKLSEEAIRQVGVVPNPMVIGGGSDANILANLGYNCA
                     ILSLGMYDVHTVNEYVNIDELYDTAKIVYHMIKL"
     gene            complement(9667..10953)
                     /locus_tag="KR294_002210"
     CDS             complement(9667..10953)
                     /locus_tag="KR294_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBH0240287.1"
                     /translation="MIVGIIGPSDSGFKIKDDLKQIDSDLKTKIYVREKVVDTIEVIS
                     KCEDECDAIIFTGCAVYEFIKSKYEISKPHSFVPRSGTSIMKAFWAIKSANIKLDKFS
                     IDVVDRYVVEDALKEFDIKATSVFCNPFSLEVGESELVEWHIKLFEENKTDIMLTGFG
                     AVYNELKERGYPVFRLQATIQLIKESYDKVKSEYALSKARFSQIAVEILSLIDYKEKI
                     DNYYSDMIKKSDMDKLVVNYVRSIQGSLFLLGRNDYVVFVHKGVADNEYNYDKLFNLK
                     REIKDMGFSLSIGIGTGVTAYQAENNAHKALRHSIDSKEIGIYLVDEDENIRGPLASE
                     NELNYSLMLSDEKVIEISKKTGMSCESVAKIIAINENRKSKIYDSKELAEYLNVSERS
                     ARRILNKIVNAGLGRICAKETSIGGGRPKNITEILF"
     gene            complement(11076..14174)
                     /locus_tag="KR294_002211"
     CDS             complement(11076..14174)
                     /locus_tag="KR294_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HBH0240288.1"
                     /translation="MDVINLIDELDEIVYVSSLDTYELLYINEIGKKAMGLNDISHLK
                     CYKALQGKDSPCEFCTNSILKEDEYYIWENTNTRTNRHFILKDKLIKWEGKHARLEIA
                     LDITEKEDISKSIAEKLEIKELLVGCIKHLITESNFSDAVNLVLTNIGKFHKADRAYV
                     FEVSEDRTKVTNTYEWCNEGVDEQKQALTNLDINELKNWFLLFEQKGFVIIDDIENIK
                     EEQPIEYEILKPQKIESLMTSSLKQDDKVVGFIGVDNPHKAVGDTSLLTSLSYFLLTE
                     MKKRKVENKLNYMSYYDFLTGAYNRNKYIKYIDNFQKGKVKSIGVVFVDINGLKDIND
                     NFGHANGDSAIVSACVIIKKYFHSYNVYRIGGDEFVVLCEDISKQLFEELVSWLSEEF
                     KDEMIYSVAVGSIWSDDNIDIHKLIKVADERMYQDKKRYYNKNKLRNNEMKVISDLAD
                     STNNILFKHKELVDKVYFDDLMIKGYSKAYEKLAYNTYDIILSICIDTNLITPIYQSE
                     SNIFSFPIKENLEKTFSYIKKYLIHPDDIILFNDNHLLKSLDSLNNSKQDDLELNFEY
                     RRLGIDKKYYWALIYMLKISSKNKLGEKQTHILVAIKNIDYLMQLHKNQKDTLTGLYN
                     YESFCEQISLMLKRYPDKRYAIIMMDIDKFKVINDIYGVRGGDKALIYVAELIQKNIG
                     SNGICCRMYADVFCIFYESYSDRDIHKVIYKIKNSLNRKKFEYMLVPCFGVYRILDNH
                     IPITNACEMAGYAHKKVKKQSINNYIFYDDTIRNDALEEKQMEREMEYALENGQFHVY
                     LQPKYNLNANKIVGAEALVRWVHPEKGIIPPIKFISLFEKNGFIIRLDMYVWEQVCSL
                     IRKWIDLGEEPVPISVNVSRLHLHNPHFKEIVLSLINKYSIPKSFLELELTESLFIKN
                     IKLFTKIIADLRMDGIVLNMDDFGSAYSSLNMLKNINIDTLKIDCGFFNEEGITDREK
                     IVLKHTIAMAKDLDMDVVAEGVETKEQAEFLVSLDCVVIQGYYYCKPIPSSDFEKLLY
                     QK"
     gene            14899..15051
                     /locus_tag="KR294_002212"
     CDS             14899..15051
                     /locus_tag="KR294_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240289.1"
                     /translation="MKIFSFLLFVVGICFCIAGFMGHSSAFSGATLSFFATTMIAVRQ
                     VKTKKK"
     gene            complement(15344..16048)
                     /locus_tag="KR294_002213"
     CDS             complement(15344..16048)
                     /locus_tag="KR294_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0240290.1"
                     /translation="MEIKPLVLIVEDDKPICKFIKVSLETQNYRCVETDNGGTAISLI
                     HSLDPDLIILDLGLPDIDGIEVIGRVRACAKTNKIIVVSAREHERDKVEALDGGADDY
                     LTKPFSVTELLARVRVALRNKAQQDNINNDAPKSFEVKNLKIDYENHIVSINGEEIHL
                     TPIEYKIIELMSKYSGRVLTHKFIIDKVWGNYYESENQSLRVFMASIRRKIEKNPAQP
                     EYILTEVGVGYRMADE"
     gene            complement(16039..17646)
                     /locus_tag="KR294_002214"
     CDS             complement(16039..17646)
                     /locus_tag="KR294_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4118 domain-containing protein"
                     /protein_id="HBH0240291.1"
                     /translation="MKKERLQHEDLKEYDYDEDGYLSKKIIIKDFIKTILVMTIATGI
                     SVVFEKVGFNESNIILVYILGVLFATSITYGYFFGILSSVIGVLSFNFFFTHPLYTFL
                     AYRKDYPMTFCIMLMAAIITSTLTSRIKREVRLSHKREKMIRLLYENNKTLLKAKNKN
                     QIIEFCGSNLVNILNRTVIVTIADENNNLGKPSIYICNNDGSENIFHSVLEKEAIKEA
                     FRTGNPVGIGTKYCKNSSAYYFPIKGQESNVLGVIGVACFKIDIITENEKILLEAVST
                     QVALAIDRENLFEKNKKANLEAERERLRGNLLRSISHDLRTPLTSILGSSSTILENDD
                     VIDKETRVELLKNIYEDTSWLTHSVENILSMTRIDEGKLDIEKRPEVVDEIIAESILR
                     VKKFANSRDIKTNIPDEIIIVHVDVLLIEQVLVNLIDNAIRHTPKNSKIELTVKKESN
                     QVLFEVADNGKGIPNEDIGNIFNRFYTKNKSRNLERRGIGLGLEICKSIVEAHGGEIV
                     AFNNPSGGATFRFSIPMYDEEGKDKWK"
     gene            complement(17900..19078)
                     /locus_tag="KR294_002215"
     CDS             complement(17900..19078)
                     /locus_tag="KR294_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240292.1"
                     /translation="MEKLSDKRRVKAVSMETFVFIVLLAVGFGYVGSIMGAGMMFKVI
                     MSTAHALLLDTVFLIMAMAVLAGALSALLSEFGVISLVNKIFKGLMRPIWGLPGASIA
                     GVVATYLSDNPAIIPFAKDKTFTQYFKKYQVPALCNLGTAFGMGLIVTTFMIAQGKEY
                     VLPAIIGNVGAIIGSIISVRIMLTFTKKYYNYDPKNDTEKQINDKGAKLEEFREIRDG
                     NVFQRTLDAILEGGKLGVEMGMAIIPGVLVVCTLVMLLTFGPSTDPATGQAVYTGAAY
                     EGIKLLPAIGDKISFIIEPLFGFTSPEAIAFPVTALGAVGAAISLVPEFIKSGAITPN
                     DIAVFTAMGMCWSGYLSTHIGMMDALDARPLAGKAILSHTIGGLCAGICAHFIFMLVG
                     "
     gene            complement(19304..19798)
                     /locus_tag="KR294_002216"
     CDS             complement(19304..19798)
                     /locus_tag="KR294_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBH0240293.1"
                     /translation="MHLFIEVIAAFFTALSFGVLFNMKGKNLILAGIGGSIAWFSYKF
                     LLNMGVTENLCFFIATVCFAIYCELCARIYMTPATTLSVCCLIILVPGYGIYNTMYSV
                     LTNNYIKAVEYGVSTLSCASSIALGLVFITTVFRKVNLYGVLTKIKENEKYKKSINKI
                     KQQK"
     gene            complement(19799..20560)
                     /locus_tag="KR294_002217"
     CDS             complement(19799..20560)
                     /locus_tag="KR294_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBH0240294.1"
                     /translation="MDIDRILNFSSNAGKAMLQSGGETYRVEETIARICQSFGIDHVD
                     VFATPTAVMASVFVDGKLHSAIKRISSRRVDLNLVHEVNSLSRAISINNLDIELCEKI
                     LDEISEDNYYSDLITIFFAGIAAATFSILFGGNVEEFIAAFTVGILTKFVIMYLSKSS
                     LNDFFVNAIGAVIIASCSILILKLGFIKTLDHLIAGAIMLLVPGLALTNALRDLLDGQ
                     LISGLAKLAEVFFVGVSIAVGMFLVLGLYFKLGGI"
     gene            21282..24116
                     /locus_tag="KR294_002218"
     CDS             21282..24116
                     /locus_tag="KR294_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH0240295.1"
                     /translation="MLRKDKVLLSLHKLCENMTLKDLQSDKTGFTTIEIANHSSLDRS
                     NTSKELNNLYNEKKVLKISGKPILFLHASIIENLIGRTLNSDEFSINNCNELLKSSKN
                     DSEDIFSTLLGHDSSLKLPIEKAKSAILYPPKGLNTLLIGPTGVGKSTFAETMYKYAV
                     ESKIFSSESKFVVFNCAEYAENANLLLSNLFGYVKGSFTGANKDKFGIVAQADGGILF
                     LDEIHRLPPEGQEMLFLLMDKGIYRRLGESDIVHKANVFIVCATTEDIHSSLLGTFLR
                     RIPVTINLPALQDRSLKERLSLIKYFFIIESKYTNATIKVHKDVIKSLLLYDCFGNIG
                     QLKSDIQLMSARAFLNYKTGLKDNIEIDLSLVPDYIYIGLLKLNENRSNLNKLSELDY
                     MLFYEFNGNNLEVEYTKELSKYNIDTSNNGFKYSTEIPYLENDIRSMFINYMEKYSTK
                     LLSISSVTHSDYTSNEIFKVINPKIYYAVEHSLKEAEKISRNKYTKQTYIALSMHISA
                     LIENINQDTYNPKYNLYNDKIFLDKDLNIAKIVLSIIENDLQTSLPKDEVKFISMFLN
                     SMYLEPNNQSESIGVIILAHGNSTASSMCDVANSLLGTNHCNAIDMPLDVKVSTILDK
                     TIELVKECDEGKGVLLLTDMGSLIAFGELISEKTKIKTRSIEMVSTPIVLEAVRKSTL
                     PEMTLDELANSLSSLNPYIGRAAIDSTEINYPEKSREYVIITTCITGYGSAMKVADFI
                     NSSLKNISKYNINLVPHNIESFKMYKNKFSNTKILAVVGSVDFNVANTPFIHIEELLN
                     GYGLDMLNKIIEGTFNANSITNIKETNLSYNSLIINFMTQNLELLDSVKLFNYVNSSL
                     FTIIELIDENLKSKFKLGYILHCSFMIERCFKNTTFPYNNITELISKNHELYSLIREA
                     FKPTEAYFNILIPDEEIAYIIDMINEYLNK"
     gene            24159..25403
                     /locus_tag="KR294_002219"
     CDS             24159..25403
                     /locus_tag="KR294_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HBH0240296.1"
                     /translation="MEDEILKGKIKQLTILALIFIFITPVFAFADTPPVPNSSRAALL
                     IDQETKRILFEKNIDEKMPLASLSKMMTFLLAIEAVDKNQVKETDMVKIDKSTASVGG
                     STCKLKDGDEISLGELMQGLMLVSGNDAAIAIAKHIGKTEKNFVNMMNKKAEEIGMID
                     TYYFNPNGLPIYTDPEHKEPPIENMSTAHDIVTLGKYMYDHYENQVTRITTMQVYNDT
                     KKDFTHYNTNPLLVSVPGVDGIKTGYTDNAGYCLAFSMMVPKDAKNERNHRLIGVVLG
                     DGNKKNRISSSATLLKYGKDNFHSKKIAHKGDIIETPCVDGIDDFKITVKVDKDLYGV
                     VSDNENINPKVVFKNMNYPIHKGDIVGVVKYYNDSGKFVGSVDVKSESNIGCIPLKDK
                     IKIKVAKINKKLEIKNSVCFKA"
BASE COUNT         9086 a         4079 c         3255 g         9602 t
ORIGIN      
        1 atcaataaac aatattaaat gaagaatatg tctgaagatt caaagtgata ctgatactat
       61 taattactaa aaaagcagta aatcttttac agatttactg cttatagtta taaataataa
      121 aactatctat aataaatgta ctatactcaa tacttcattc aatatagtaa taacaaatct
      181 actttattcc tatgtaaata tgaatttctt gtttctttgt atcaaaagta ttacattgat
      241 actcttcaaa atcacttata taagtcctat caaaatccat ttgccaaaac ttaaaccaaa
      301 aatctcctac ttctttttga cctcctacta taacaaactt tgcatactta cctgctggta
      361 taactttact aataatactt tctccaacag tattattagt gtttaattct tctaaattct
      421 tctctttatc agaattacta tttacttcac aacatgcaac aaagctatac ggacttgtaa
      481 aatcaccctg gtaatctgta tatagaccta ttgtcttgtc attcttttta ccctttatag
      541 cattatatat ccctttgccc ataaattttt tccacaattc acctatatca tttatcgctt
      601 gtccatcttt atttgtagtc tccttcgata ttcctataac tattttctca tttatctcta
      661 ctatttcata attcatactt tatacctcac tttgttttta ttaatctatt ttattttgaa
      721 ctaattcaat tataatttat aatatacgac acctttatgt catattttta atataattaa
      781 actcagtgag atattatata ctaaatgcaa gatattatat atttaataaa atctttaatc
      841 tagcattata ttataatgaa taaattttag acaactccct tagtctagtt attacattat
      901 ccctaacatc tttaggttca agtacttcaa cattgtcacc aaatgataaa atatatccat
      961 aaatccattc accaatagga aattctgtaa ttacatcata tgtatcatct tcatttttag
     1021 ttattaaatc cttattaaaa tcatcaaata ctctaaaaag catcttttct ttaaacctca
     1081 atttcaacgt tatagtattt tccttaatta ctttagaatc attcaaacat acttcttcta
     1141 ttatctttct tgaaaatact tcatccttta tagataaatt ccttatccta ctaattctaa
     1201 atatcctaaa atcatctttt agtttacaaa atccatacaa gtaccaagtc ttactcttat
     1261 acataagctt cagtggttcg acagttctat ttgtctggct tgacaaacta tttacataat
     1321 taaaatttat agtattacgc cttaaaatag cttcttttat ttttgtaaat ttatcatctt
     1381 cattaaaatt acttccccat tcagtaaagt ctatttcaat ccagtttgaa aaattctgct
     1441 ctccaaatat tgagccaatt ttatttacta ctgaatttat ttctggatac ttagtcgcct
     1501 gtaatgtttt cagtgccact attaaactct ctttatcttt ttttgacaat atagccttgt
     1561 ctatagaata ttcttctatt aaagatatcc ctcctccttt gcctttcgtc atatatactg
     1621 gtactcccga catagacaga gtttctatat ctctatatat ggttcttgta gaaacttcaa
     1681 atctatctgc caactcttta gctgttacta attttttatt taatagaatt actattattt
     1741 ctgttaatct atttattttc attcattacc acctactaaa attattaaat ttatttaatc
     1801 taaattaatc atactaattt ttaaataaat aaaatcttag aatcttatct aaattattct
     1861 tacatgattt tatttacttt ctattatctt tctcactttg gatattatca tcttaattta
     1921 tttattacta tatcaattta cttattatca tctcatttgt tatcgtctta cttaatttac
     1981 ttatttctat atcaattcac ttattattac ctcacttgtt atcatcttac ttaatttact
     2041 tatttctata tcaatttact tattatcatc tcatttgtta tcgtcttact taatttactt
     2101 attgctatgt caattcattt attattatct cacttgttat cgtcttattt aatttactta
     2161 tttctatatc aattcactta ttatcatctt aattcatttg attattatca tttactttat
     2221 tcaatttcta tatcaaaaat tagtatttgt acttaatact taaaattaat ttaaagtctt
     2281 tacatattat ttatttttta ttgtaatatt aatttccata ctttgctaag ctacttccac
     2341 tcatttattt taaaatttca atttactatt tctcaattct atattattat ttttcaattt
     2401 tatattacta attttaaagc tttttagcta ttattcctac aatatttaaa caatttttta
     2461 ataataaagc tatattacaa tatattcaaa atatgtaata ttttagatat ttttcgttga
     2521 caatgttaaa tttttgtttt atccttaatt aaggacatgt tattgacatt tctgaaactt
     2581 atttgaaata gttttttcat tttatttagg aaaacgtatt atacttaaga aaacgtattt
     2641 tctcatttca gataagtaaa atatttattc ttttggggag gaaatcatgg aaattaataa
     2701 aaaacatttt attcaagtat ttttaacttg cttaatcttg gtagtaatat gtgaatttat
     2761 agggcaaaga actatagcta ttggaaaagc ctctatagta ctgttcccta tgctttatgc
     2821 agttataatt ggacttataa taacaccaga tttattaggt aaaaaaatta aagcacttaa
     2881 aaaagtggtt ggagaaaaag aaataaatat tgctggtgaa gttgttggaa ttgcactagt
     2941 aatgcttggt ataaaatatg gtactacagt tggaccaaac attgacaaaa taattcaagc
     3001 tggaccagcg tttatcgctc aagaatttgg tcatatactt gcaccaatcg ttgcattacc
     3061 tcttgcatta atgtttggaa tgaaaagaga agctgttgga gctactgcaa gtataagtcg
     3121 tgaaccttct ttaggagtta tatcagaaaa atatgggata aactcaccag aaggtagtgg
     3181 tgtacttggt acatatttaa tgggaacagt tcttggtact atatacttta gtgtactagg
     3241 ttcaatatct atttatagtg gtcttcaccc atatgctttg ggaatggcct gtggtgttgg
     3301 tagtggaagt atgatgacag cagctgctgg ttcattatct accatggtac cacctgaaat
     3361 ggcagataca atacttgcct atgctgcaac aagcaatatg atgtctagta taacaggaat
     3421 tatattctta gtttttgtat ccttaccatt tactaatttt atgtataaga ttttagaacc
     3481 aaaattttcg agaaataaaa aaactaaaga aattaaatct acagaaggag agtgctaata
     3541 aatgtttgct aatttaaatt taaagaaaag ttcatatcaa ttattggtta tgtctgttat
     3601 tggagttata attcttatag gacaaagaat tagcgttggt acatctatag ttacagctct
     3661 tcctggtatg gtgatgctaa tattagctgc tatggcagct atgattataa aagatttatt
     3721 tcctaaatca atctttccag cttttggatt tgcaactata atcggccttt tacttagtat
     3781 gccatatagt ccaacatctg aagtattctt aactaacact aataatatta actttatggc
     3841 tataactact ccactactag cttttgcagg aatttctgtt ggaaacaaaa tagaagcttt
     3901 aaaagaaatg tcatggaaaa tagttataat ttcacttatt gtatttacaa ctatattctt
     3961 tgcatgtgcg agtatagctc atatagtttt aagtattcaa ggtaaaatat aggaggaatt
     4021 tattatgaat aaagaacaat taaaatctct agtaataaaa actatagatg aaaatagaga
     4081 aaaaatatta aaaataggtc aaggaatata caaaaatcca gaatatggat ataaagaatt
     4141 taaaactaca gaagctgttt caaacttttt tgaacaagaa ttaaatttat ctgtagaaaa
     4201 aaatatagca gttacaggat gcaaagcaga tgcaaattct agcaagaaag gtcctcatat
     4261 atctatactt ggagaattgg atggtatatc atgtaaagaa cataaagatg ctaatgaaat
     4321 aggtgcttct catacttgtg gacataatat tcaaatagct ggaatgttag gtgctgctgt
     4381 tggtttagta aaaagtggcg ttttagaaca tttagatggt aaagtatctt ttatggctac
     4441 tcctgctgaa gagtttattg agttggaata cagagagcaa ttaaaaaaag aaggaaaaat
     4501 aacttatttt ggtggaaaac aagaattaat aaaaagaggt tattttgatg atatagacat
     4561 atctatgatg tttcatgctt ctgatttagg agaagataag gctctagttg gtcctgagag
     4621 taatggattt gttggaaaaa aggttaaatt tataggtaaa gaatctcatg ctggttctgc
     4681 tccacatgat ggaataaatg ctttaaatgc agcaatgctt gctataaaca acgtgaatgc
     4741 acttagagaa acttttaaag agtctgaaag agttagattc caccctatca tcacaaaagg
     4801 tggagatata gtaaatgttg ttcctgctga tgttcatatg gaatcatatg ttagagctag
     4861 aactataaat ggtatgattg atgctaatga aagaataaat aaggctttga tggctggtgg
     4921 aatggcagtt ggagctgatg ttgagataac tgaaattcct ggatatcttc caatattacg
     4981 atacaaaagt cttgataatt tatttaaaaa caatcttgaa gatttaggtc taaaaggaaa
     5041 agttattgat ggtggagatt ttacaggctc ttttgatttt ggagatgtgt ctcatataat
     5101 gcctactctt caccctatga ttggtggtgt aaaaggagct cttcatacaa gagattttga
     5161 aatagttgat gaagatttag cttacataat tcctgctaaa gcaatggcac ttacagttgt
     5221 agaccttctt tttgataatg ctaaggatgc taaagatata ttagatacct ttactccagt
     5281 tatgactaaa gaagaatatc taacattctt agaaaaacac gataaaactt tataagtcta
     5341 tttttataat agggtggtat ctactgtaaa agttatacca ctctttgttt ttgtaacagt
     5401 atacttcttt tcttttagtt tttagattaa actaagatat attatcctcc ttaaaacttt
     5461 tagagctacg ttgaaatatc agtagaacta tgctatattc tttctaatta atataaattt
     5521 ctattctaat tcaaggtggt gaaaaaatgt ttaatgcagg aaatcgaatt ataaatacat
     5581 ggttgtaccc tattcaagat gactttgtct tgattgatac tggatatgaa aatggtttta
     5641 aacatttcaa aaaacgaatt tctaaattca acataaaaat caaagatatt cgatacatat
     5701 ttctaactca tgctcatgat gaccatgttg gttttctaaa tcagattcta gacgaatctc
     5761 ctaatacaaa gattgttatg catgataaag ctttagaaat tctatataaa ggtcaaaact
     5821 cttttattgg tggttgtacc agccgtactg cctttctctt ttgccaaatt atgaaactat
     5881 ttggaaaagg tgagcatagt ttttctccac ttaaacaaga atttgaaaaa aggtgtattc
     5941 ttgtgtctga caataatcgt aaagaaattg aaaaagaact aaatggaaaa attatagata
     6001 caccaggaca tactgctgat tcaatttcac tactaattga tgatggtgtt ttattttgtg
     6061 gagattctgc aatgaatgga tttccaagta ctcacaaaat taccatattt gcagaaagca
     6121 aactagaatt tattcaatct tggagaacaa tcatcaatac aaaacctaaa atgatttatc
     6181 ctggacatgg aaaaccattt gaatacagta aattagaaca aaatctaatc tatgtaaata
     6241 aaataaattt atatcctcta cataattcaa aagatattca cagatttttg tagaaaatac
     6301 aaagtaaatt tctttgatta attaaaaacc taacacttta ctacgctact tattttaata
     6361 acttaatctt ccactagctt ttcataaaat tttgttttaa aattaatttt aaagtgcata
     6421 tgttatttaa atacattaga tataattcgt cattaatcta cttaaagcat atttaactaa
     6481 caccactcaa ccagaaaatt cagaaaactg cattgacaca ggaaaaagtt tattttatac
     6541 tttttttagg acatattgtg gacacgtctt aaatcgacaa gcagaattta aattgtaaga
     6601 ttaaccacaa tacttatttt ttaattatat ttttaaacat tagggaggat attatgaatg
     6661 ataacgtagt taagaagaaa aacttttttg acaggacatt aaacagaata gaaactgttg
     6721 gtaataaact accagaccca gttacaatat ttttagggtt atgtgtactt ttacttatac
     6781 tatctagtct agttggttct atgggtatat cagtagttca tcctggtact ggagaaacta
     6841 taaccgctgt aaatttattg actgtagaac agcttcaaat tcttttagga aacatagtca
     6901 gcaatttcca agggtttgct cctttgggtc tagttctagt aactatgata ggtgctggtg
     6961 tatgtgacaa aacaggactt atgacagcaa caatcaaagc atcagtaagc aagattcctg
     7021 aaacaagagt aactcttgtt gtaatgacta taggtatgct tgccaatata gcttcagatg
     7081 caggtacaat attatttcca ccattagctg cacttgtata tcttggtgtt ggtagacatc
     7141 cacttatagg tttattttct ggatatgcag cagtctgtct aggatttgcc gcaaacatta
     7201 tgataagtgt caatgatata cttgctgcaa gttttacagt tccagcagct caaatgattg
     7261 attctggatt tcaagccaat gcaacaatga acttattttt tatgatagca tcaacgtttg
     7321 ttctaatact tttggcaaca tgggtaacag aaaaaattgt agctcctaga tttggtaaat
     7381 atgaaggaaa tgcagaacta gatgttgatg gaagtcttag tgatgtagaa aagaaagggc
     7441 ttaaaaaagc tggtataagt atattaatat atgtggctat tatagtagct cttagtgtaa
     7501 tcggtaaaaa accattctta gctgacccag aaacaggaga tttactatca aacaatgctc
     7561 ctcttatgaa aggtatggta cctataatag cactagcatt tttcatacct ggtgttgtat
     7621 acggaaaaac tataggtaaa ataaagaagg ataaggatgt agtctctata atggctagtg
     7681 caatgagtga tatgggtgga tatataatac tagcatttgc tgcttcacaa tttttgcaat
     7741 tattcacaaa tagtaattta ggtctgatac tagctgtaaa gggcggagaa tttttaaaat
     7801 cagcaggaat aaatggacct ttattgttga taggatttat tatattatca tgttttataa
     7861 atttatttat aggtagtgca tctgcaaagt gggctattct tgcacctata tttgtaccaa
     7921 tgtttatgat ggttggatac aatccagcac ttactcagat ggcttatcgt ataggtgatt
     7981 gtataacaaa tccacttagc ccattatttc cgtacttccc tattatacta gcattcacaa
     8041 gaaaatacga taaagatgct ggtatgggta ctgtaattgc taatatgata ccatactcta
     8101 tatcattctt aatagtgtgg actatactac taatattgtt tatggtattt aatattccac
     8161 taggacctgg aatacttcct tcatatagca tgtaatttat ttaaatcttt ctaaaaggag
     8221 aaataattta tgttagataa aaatagactt ataaataatt ttatggatat ggttagaatt
     8281 gatagcccat ctaatcaaga attagaaatg tctaagtggt tggtaaacta cttaaaagaa
     8341 agaaatatag acgccattat agatgatgca ggtgaaaaat atggtggtaa tacaggtaat
     8401 gtcattgcct atataaaagg tgaagaagga agtagaccac tttgtttatg tgcacacatg
     8461 gaccaagttc aaccttgttt aggtgtaaaa ccaatactag atggtaatgt agttagaagt
     8521 gatggaacta ctacacttgg tgcagatgat aaagctggaa tagctgctat acttgaagct
     8581 ttagaacatg ttattacaga aaaaatacca catagagata tttatctttg ttttacaatc
     8641 tgtgaggaag ctggtatgta tggtgtcaaa aactttaatc ctgacaactt gccttgtaaa
     8701 gatatggtga ttttagattc tggtggagct attggttcga tagcatacaa agctcctgct
     8761 caacaatcta taaaaatctc ttttcatgga aagaaagcac atgctggtat agaacctgaa
     8821 aaagggttaa atgctatatt agtagcctct catgcaataa gcaacatgca cataggcaga
     8881 atagattcat tgactacttc aaatataggt aaaatagaag gtggtggagc tacaaatata
     8941 gtaactgata aggttacatt gactgctgaa attaggtctc atatacctga aactttagag
     9001 tatgagctta atcatatgga aaaatgttgt aaggatgctg catctaaatt taatactact
     9061 tatacttttg aacataatat gtcttaccct agttttgaac ttagtagaga tagtcacgtt
     9121 ttcaagttaa gtgaagaagc aataagacaa gttggtgttg ttccaaatcc aatggtaatt
     9181 ggtggtggaa gtgacgcaaa tatattagct aatcttggat ataattgtgc tatattaagt
     9241 ctaggtatgt atgatgtaca cacagttaat gaatatgtaa atatagacga attatatgat
     9301 actgccaaaa tagtttatca tatgattaaa ttataaatat cataatataa ctctttaaat
     9361 tataaaaata aaaacctatg tatcttcaac tttataagtt atatattaaa gttgttttac
     9421 ataggtttta gtattttata taataatttg ttttaacatt tttcataata agcttcaata
     9481 ttttgcataa taatttgttc tagcattttt aataacaagc tttagtattt tatattaata
     9541 atttattcta gtattttaca taatcatttg ttctaatttt tttcataata agctttaata
     9601 ctttatatag taatttgttg tagaatttta tacaatataa tgatttatac agttttataa
     9661 aatatcttaa aacagtattt cagtaatatt ttttggtctt cctccaccaa tactagtctc
     9721 ttttgcacat attcgaccta aacctgcatt tactatttta tttaatatac gtcttgcact
     9781 tctttcactt acatttagat actctgctaa ctcttttgaa tcataaatct tactttttct
     9841 attctcattt atagcaataa tttttgcaac tgactcacaa ctcattccag tctttttaga
     9901 tatttcgatt accttttcat cagatagcat caaagaataa tttaattcat tttcggaagc
     9961 taaaggtcct cttatgtttt catcttcatc taccaaatat ataccaattt cttttgaatc
    10021 tatggagtgt cttaatgctt tatgtgcatt attttcagcc tgatacgcag ttactccagt
    10081 accaattcct atactaagag aaaagcccat gtcttttatc tctctcttta gattgaatag
    10141 cttatcataa ttatactcat tatcagctac ccctttatga acaaatacaa cataatcatt
    10201 tcttccaagt aaaaataagg aaccttgaat acttcttaca tagtttacta caagcttatc
    10261 catatctgat ttttttatca tgtcagaata atagttatct atcttctctt tataatctat
    10321 taaactcaat atttcaacag caatttgaga aaatcttgcc ttacttagag catattcact
    10381 ctttaccttg tcataacttt ctttgattaa ttgtatagta gcttgtaaac gaaatacagg
    10441 atagcctctt tcttttaatt cattatatac tgcaccaaaa ccagttaaca ttatatccgt
    10501 cttattttct tcaaataatt ttatatgcca ttctacaagt tcagactctc ctacttccaa
    10561 agaaaatgga ttacaaaata cactcgttgc tttaatatca aattctttaa gtgcatcttc
    10621 cacaacatat ctatcaacta catctatact gaatttatct aattttatat ttgcactttt
    10681 tattgcccaa aatgccttca ttatactcgt cccacttctc ggtacaaatg aatgtggctt
    10741 acttatctca tacttagatt ttataaattc ataaactgca catcctgtaa atataatagc
    10801 atcacattcg tcttcacatt tagaaataac ttctattgta tctactactt tttctcttac
    10861 atatatttta gtctttaaat cactgtctat ctgttttaaa tcatccttta tcttaaaccc
    10921 agagtctgaa ggacctataa tacccactat cataaacttc gctcctaatc cataaatatt
    10981 atacttttta aaaattatat cctcactatt ttctacttct atttaattat tttgaactac
    11041 tccatcctac ctacatttag aatggaataa ttagcttatt tttgataaag taacttctca
    11101 aaatcagaac ttggaatagg cttacaataa taataacctt gaattaccac acaatctaaa
    11161 ctcactaaaa attcagcttg ttcttttgtc tctacacctt ctgccactac atccatatct
    11221 aaatcttttg ccatggctat agtgtgcttt aaaactattt tttctctgtc tgtgattcct
    11281 tcctcattaa agaaaccaca atctatcttt aatgtatcaa tattaatatt ttttaacata
    11341 tttaatgaag aatatgctga accaaagtca tccatattta aaacaatacc atccattcta
    11401 aggtcggcta ttatcttagt aaataatttt atatttttaa taaataaact ttctgtaagc
    11461 tctaattcta aaaaagattt tggtatacta tatttattta ttaaacttaa aacaatttct
    11521 ttaaaatgtg gattatgcaa atgtaatctt gatacattta cagagatagg aactggctct
    11581 tcacctaaat ctatccattt tctaatcaaa gaacatactt gttcccatac atacatatct
    11641 aatctgataa taaacccatt cttctcaaat agtgaaataa atttaattgg aggtattata
    11701 cctttttctg gatgaaccca tctaaccaat gcttctgcac caacaatttt atttgcatta
    11761 agattatact taggttgtaa atatacatgg aattgcccat tttcaagtgc gtattccatt
    11821 tccctttcca tctgtttttc ttcaagtgca tcatttctta tagtatcatc ataaaatata
    11881 tagttgttga tactttgttt ctttactttt ttgtgagcat atcctgccat ttcacacgca
    11941 tttgtaattg gaatatgatt atccaaaatt ctataaaccc caaaacatgg tactaacata
    12001 tattcaaatt tttttctatt taagctattt ttaatcttat aaattacttt atgaatatct
    12061 ctatcagagt aactctcata aaaaatgcaa aatacatctg catacatacg acaacatata
    12121 ccattagaac caatgttttt ttgaatcaac tctgcaacat atattaaagc tttatctcct
    12181 cctctaactc cataaatgtc attaattacc ttgaacttat ctatatccat cattataatt
    12241 gcataacgct tgtcaggata tcttttaagc attaaactta tttgttcaca aaaactttca
    12301 taattgtata gtcctgttaa tgtatctttt tggtttttat gtagttgcat aagataatct
    12361 atatttttta tagcaactaa aatatgtgtt tgtttctcac ctaacttatt tttactacta
    12421 atctttaaca tataaattaa tgcccaatag tactttttat ctattcctaa acgtctatac
    12481 tcaaaattta gttctaaatc gtcttgcttg ctattattaa gactatcaag agattttaga
    12541 aggtggttat cattaaataa tattatatca tcaggatgaa ttaaatattt ttttatgtat
    12601 gaaaaagttt tttcaagatt ttcctttata ggaaaactaa aaatattgct ctctgattga
    12661 taaattggag taattaaatt cgtatcaatg caaatagata aaattatatc atatgtatta
    12721 taagctaatt tttcataagc tttagaatac ccttttatca ttaaatcatc aaaataaacc
    12781 ttatcaacta actctttatg tttaaataaa atattattcg tcgaatcagc taagtcacta
    12841 attactttca tttcattatt tctaagtttg ttcttattat aatacctctt cttatcttgg
    12901 tacattctct catcagcaac tttaattagc ttatgtatat caatattatc gtcactccaa
    12961 atactgccca ctgctacact atatatcatc tcatccttaa attcttcact taaccaactc
    13021 actaattctt caaatagttg ttttgatata tcttcacata atacaacaaa ctcatctcct
    13081 ccaatacggt aaacattata agaatgaaag tattttttta ttattacaca tgctgacaca
    13141 atagcagaat cgccattagc atgtccaaag ttatcattaa tatcttttaa cccatttata
    13201 tctacaaata caactcctat ggatttaact tttccttttt gaaaattatc tatatactta
    13261 atatatttat ttctattata tgcaccagtc aagaagtcat agtagctcat ataatttaat
    13321 ttattttcta cttttctttt tttcatctca gttaataaaa aataagatag ggatgtcaaa
    13381 agagaggtat ctccaacagc tttatgtgga ttatcaactc caataaaccc tactacttta
    13441 tcatcttgtt ttagtgaaga tgtcattaaa ctttcaattt tttgaggttt taaaatttca
    13501 tattctattg gctgttcttc ttttatattt tctatatcat caattattac aaaacctttt
    13561 tgttcgaata ataaaaacca attctttaat tcattaatat caagatttgt tagtgcctgt
    13621 ttttgttcat caacaccttc attgcaccat tcatatgtat tagttacttt tgttctatct
    13681 tctgatactt caaaaacata tgctctatca gctttatgaa atttaccaat attggttaat
    13741 acaagattta cagcatcaga aaaattagat tctgttataa gatgtttaat acatccaact
    13801 aataactcct ttatctctaa tttttctgct attgacttac ttatatcttc cttttctgta
    13861 atatcaagag ctatttctaa tcgtgcatgt ttgccctccc atttaattaa cttgtccttt
    13921 aatataaaat gtctatttgt tcgagtattc gtattttccc atatgtaata ttcatcttct
    13981 tttaaaatag agtttgtaca aaattcgcag ggagaatctt tcccctgtaa tgctttataa
    14041 cattttaaat gggatatatc attaagtccc attgcctttt tcccaatttc attaatatat
    14101 aaaagttcat atgtatctaa agaagaaaca tatacaattt catccaactc atctattaaa
    14161 tttattacat ccatttatat atatctcctt ttattcattt tccagattga atttttaaag
    14221 cttttaaaat tttgctatat atttggcaat gatattatac ttctttatgt tttaaaatag
    14281 taccttaatg aggttctatt ttttagtaaa tagaattatt attgtgtcaa tcgtacaata
    14341 gagttttgta atacttaatt taatatattt ataattaact atcttattat gtatttacaa
    14401 ttaattctca tataaatgac aaatctccac ctcaattaag tattccaatc atatatgagg
    14461 ataatacttc attcatttaa aaatataaaa ctattatata ttaaaatttc ttcaataata
    14521 aattatttag attgttactt tgatatatta tataatatca caaaggctga tataaaaaga
    14581 caaaaagggc aattttttta tatcaaaaaa aatgttaaat tgatattatc catatataaa
    14641 ttgatattat ccatataggt gctatattta acaattctac ttacttccct tacacttatt
    14701 agcatatagt tattaagagt ttgttgcaaa acaacactta gcacacttta aaaagtgtgg
    14761 tctaataagt aatcaacgaa gaagacataa taaagcataa aataggatat acttttccac
    14821 gtcatcaaaa ttgaggattt tattattaat atatgataaa atatgcttaa taaattaaat
    14881 tttaatggga gaatagttat gaaaatattt agtttcttgt tgtttgtagt gggaatatgt
    14941 ttttgtattg ctggatttat ggggcattcc tcagcttttt ctggtgcaac attgagtttt
    15001 tttgcaacta caatgatagc tgtaagacaa gtcaaaacta agaaaaaatg aaataggcaa
    15061 atcctaactt tataagttaa tattacataa gtaattagtc taaaattaga tactttttct
    15121 attacaaaaa tacatcatcc actttgtatt ctcttaaaaa aaataaaata gctatgtaaa
    15181 ttcaagatta gatagactaa ctctctatcc atttcattgt aaaatataca tagctatttg
    15241 tattcgattt aaaatactta gattttctta cataacaaat aatttctatc tgattattac
    15301 tcatgttcat ttattaacca ctcagcaact aatcatttag tatctattca tccgccatac
    15361 ggtaacctac cccaacctca gtcaaaatat attctggctg agcaggattc ttttcaattt
    15421 tccttcttat acttgccata aaaactctaa gcgactgatt ttcactttca tagtaatttc
    15481 cccaaacttt atctattata aacttatggg ttaagactct tcctgaatac ttagacatca
    15541 actcaataat cttatattcg attggagtta aatgtatttc ttcaccatta attgacacaa
    15601 tatgattttc ataatctatc tttaggtttt taacttcaaa agactttgga gcatcattat
    15661 ttatattatc ctgttgagct ttatttctaa gagccacacg tactctagcc aaaagctctg
    15721 ttacactaaa aggtttagtt aaataatcgt ctgctcctcc atctaaagct tccaccttat
    15781 ctctctcatg ctctctcgct gaaacaacaa ttattttatt agtctttgca catgccctaa
    15841 ctcgtcctat tacctcaatc ccatcaatat ctggtagtcc taaatccaaa attatcaaat
    15901 ctgggtcaag agaatgtata agtgatatag ctgttcctcc attatctgtc tctacacacc
    15961 tataattttg agtttcaaga gatactttta taaatttaca aattggctta tcatcttcta
    16021 caattagaac taatggcttt atttccactt gtctttcccc tcctcatcat acataggtat
    16081 gctaaatcta aatgtagctc ctccagaagg attattaaag gcgacaattt ctccaccatg
    16141 agcttctact atagatttac atatctccaa tccaagacca atacctcttc tttcaagatt
    16201 tctagactta ttcttagtat aaaacctatt aaaaatattc ccgatatctt catttggtat
    16261 tccttttcca ttatctgcaa cttcaaatag tacttgattt gactcttttt ttacagttag
    16321 ttctatctta gaatttttag gtgtatgcct tatagcatta tcaattagat ttactaacac
    16381 ttgttctatt aataatacat ccacatgaac gattattatc tcatctggaa tatttgtttt
    16441 tatgtctcta ctattggcaa actttttgac tcttaatata gattcagcta ttatttcatc
    16501 aacaacctct ggtcgttttt caatatccaa ttttccttca tctattctgg tcatactaag
    16561 tatattctca acagaatgag ttagccaact cgtatcttca tatatatttt tcaataattc
    16621 tactctagtt tctttatcta tcacatcatc attttcaagt attgttgaag atgaacccaa
    16681 tatacttgta agtggagttc ttaaatcatg agaaattgac ctaagcaagt ttcctcttaa
    16741 cctctctctc tctgcctcaa ggtttgcttt tttatttttc tcaaataaat tttctctatc
    16801 aattgccaac gcaacctgtg ttgaaactgc ttctaatagt atcttttcat tttctgtaat
    16861 aatatctatc ttaaaacacg caacacctat aacaccaaga acatttgatt cttgaccttt
    16921 tatagggaaa taatatgcac tgctgttttt acaatatttt gtcccaattc caactgggtt
    16981 acctgtccta aaagcttctt ttatagcttc cttttctaat actgaatgga atatattctc
    17041 acttccatca ttgttacaaa tataaatact tggcttacct agattattat tctcatctgc
    17101 aatagtcact attacagttc tatttaatat atttactaaa ttagacccac aaaattcaat
    17161 aatttgattt ttattttttg ctttaagcaa cgttttgtta ttctcataga gcaatcttat
    17221 cattttttct ctcttatgag aaagtctcac ttctcttttt atcctagaag ttaaagtact
    17281 tgttataatt gctgccatta gcataataca aaaggtcata ggataatctt ttctataagc
    17341 taaaaaagta tataatggat gcgtaaagaa aaaattaaat gatagcactc ctattactga
    17401 agaaagtatt ccaaaaaaat atccataggt tatacttgta gcaaatagta cacctaatat
    17461 gtatactagt ataatattag attcattaaa acctaccttt tcaaaaacta ctgatattcc
    17521 agtagcaatt gtcataacca atatagtttt tatgaagtcc ttaataatta tctttttact
    17581 gagatagcca tcttcatcat aatcatactc ttttaagtct tcatgttgta gtcgttcctt
    17641 tttcatttac tacaattcct ccttattgtt actgtttaaa ttggctctat tttatataat
    17701 acaattttat cataataaat tcaatcaata catttaatta atgtacttaa attactaaaa
    17761 ggtgctgtct taaaatgaaa ataaatctct atttcaaaac agcacctata tatttaaatt
    17821 actaatttag tttttacata cttaaatcaa tagttttatt caatttcata aattataata
    17881 cttcaattat aaaacatttc tatccaacaa gcataaatat aaagtgggca catatacctg
    17941 cacataaacc acctatagta tgcgaaagta tcgctttacc agccaatggt cttgcatcta
    18001 aagcatccat catacctatg tgtgtactta aatatccact ccaacacata cccattgctg
    18061 tgaatactgc tatatcatta ggagttatag cgcctgattt tataaactct ggtactaaag
    18121 atattgctgc tccaacagct cctaatgcag ttacagggaa tgctattgcc tctggtgatg
    18181 tgaatccaaa taatggttct attatgaagc taatcttatc accaatagca ggtaataatt
    18241 ttataccttc atatgcagct cctgtgtaaa cagcttgacc tgtagcaggg tctgtagatg
    18301 gtccaaaagt taataacata actaatgtac aaactactaa aactcctggt attatagcca
    18361 tacccatttc aacacctaac ttaccacctt caagtatagc atccaatgtt ctttggaata
    18421 cattaccatc ccttatttct ctaaactctt caagttttgc acctttatca tttatttgct
    18481 tttcagtatc atttttaggg tcataattat aatacttttt agtaaaagtc aacataattc
    18541 taacactaat aatactacct attattgccc caacattacc tattatagct ggtagtacat
    18601 attctttacc ttgagctatc ataaaagttg ttacaataag tcccatacca aaggctgttc
    18661 ctaaattaca taaagcaggt acttgatact tcttaaaata ttgtgtaaat gttttgtctt
    18721 tagcaaatgg tataatagct ggattatcag ataaatatgt tgcaactact cctgctatac
    18781 tagcaccagg taagccccat ataggtctca taagaccctt aaatatctta ttaactaaag
    18841 atattactcc aaactctgaa agcaatgcac taagtgcacc tgcaagaact gccatagcca
    18901 ttattaaaaa tactgtgtct aataaaagcg catgtgctgt actcattatt actttaaaca
    18961 tcattcctgc acccatgatg cttcctacat atccaaatcc taccgccaat agtacaataa
    19021 atacgaaggt ttccatactt actgccttga ctcttctctt atccgacagc ttttccatct
    19081 tgaaatcttc ccccttttaa ttttaaatta aggttcctaa cattggtaca aattttttgg
    19141 tacaaactga gttctaaaac ttacactcgt aatgcaagtt gtcagttttt tgaaataaaa
    19201 aaaaattacg tttatagaat aagaatatcc tctttaattt ggatactctt attctatttt
    19261 atgttattat attatcatcc ttttgtttaa aagtcaattt tttctatttt tgttgtttaa
    19321 ttttatttat actcttttta tatttttcat tttcttttat ctttgtaagt actccatata
    19381 agttgacttt tctaaataca gtagttataa ataccaatcc taatgcaatt gaacttgcac
    19441 acgataatgt actcacccca tattctacag cttttatata attattggtc aaaacagaat
    19501 acatagtatt atatattcca taacctggca ctaatattat taaacagcaa acacttaatg
    19561 tagttgctgg agtcatataa attcttgcac ataactcaca atatatcgca aaacaaactg
    19621 tagctataaa aaaacataag ttttctgtta ctcccatatt taaaagaaat ttatacgaaa
    19681 accaagctat acttccaccg attcctgcta gtattaagtt ttttcctttc atattaaata
    19741 gcactccaaa gcttaaggca gtaaaaaaag ctgctattac ttctataaac aaatgcactt
    19801 atatcccccc taacttgaag tacaatccaa gtaccaagaa cattcctact gctatagata
    19861 cacctacaaa aaatacttct gctaattttg caagaccaga aatcaactgt ccatctaaca
    19921 aatctcttaa tgcattagtc aaagcaagcc cgggaactaa gagcattatt gctcctgcta
    19981 ttaaatggtc taacgtcttt atgaatccga gctttaaaat taaaattgaa caagaagcta
    20041 taataactgc tccaattgca tttacaaaaa agtcattaag ggaagattta cttaaataca
    20101 taataacaaa cttagtcaga atcccaacag taaatgcagc tataaattct tccacatttc
    20161 ctccaaataa tatcgaaaaa gttgctgctg caatacctgc aaaaaatatt gttattaaat
    20221 ccgagtaata gttatcttca cttatttcat ctaaaatttt ctcacataat tcaatatcta
    20281 aattatttat acttattgct cttgataatg agttaacttc atgaaccaag tttaggtcta
    20341 ctcttcttga gcttattctt ttaattgctg aatgtaattt cccatctaca aatacagatg
    20401 ccattacagc tgttggagtt gcaaatacat ctacgtggtc tattccaaaa gattgacata
    20461 ttctagctat cgtttcttca actctatagg tttctcctcc actttgcaac atagctttac
    20521 ctgcatttga ggaaaagttt aaaattctat ctatatccac aaaacatatc tcccattctt
    20581 ttatagtatt attcatattt taatacaaga tattatttat ttaaactatt ttaaataatt
    20641 catatccaac atttacattt tatgaaaaaa cttgtttttt atgcttgtca aaatcaaatt
    20701 ttaagcttgt ttacaccata aaatggctga attaatattt gacaaacact ttcaaccatt
    20761 tatataacct tctaaattgt ataacttttt actacaaata aaattatatc tcttttaatt
    20821 ctttctcttg agtatttagc ttatagtaac ttcatattta tatatgtaca atataaaaca
    20881 ttatttttat gatacaaaat ataatttgta aatgtatata tgtattaact gtgtatatat
    20941 aaattattct taaccttatc agttttttca tatatcttca tctataccga ccatatatta
    21001 attacattga ccatatatta ataaatgata ttacatagac ttaagtatat taaaaaactt
    21061 aaatttagtt atttaacaac ataatactct aatttaatct ataaaaatcc atacctaata
    21121 taatgcaact cttattttaa caccatctat tacacaaaac aacatattaa aaagtaaaat
    21181 acaaaatatc tactataaac cttattttaa tactgaatat atattataat atatttaatg
    21241 tagcttaaat atagtttaaa cataaagaaa ggaaacggta tatgctaaga aaagataaag
    21301 ttctattatc tctacataaa ttatgtgaaa atatgacttt aaaagacctt caatcagata
    21361 aaacaggatt cactacaata gaaattgcta accattcatc tcttgataga agtaatacca
    21421 gtaaagaatt aaataaccta tacaatgaaa aaaaagttct gaaaatatct ggtaagccaa
    21481 ttttatttct acatgctagt attatagaaa atttaattgg ccgtactttg aacagtgatg
    21541 aattttctat aaataattgt aatgagctac ttaaatcaag taaaaatgac tcagaagata
    21601 ttttttcaac attacttgga catgattcta gtcttaaact acctatagaa aaagctaaat
    21661 ctgctatact ctatcctcca aaaggtctta atacattact aataggacct actggtgttg
    21721 gaaaaagtac atttgctgaa acaatgtaca aatatgctgt agaaagtaaa atcttttctt
    21781 ctgaaagcaa attcgtagta tttaactgtg ctgaatatgc agaaaatgct aacttattat
    21841 taagtaattt atttggttat gtcaaaggtt cttttactgg tgctaataag gataaattcg
    21901 gcatagttgc acaggctgat ggaggcatat tattcttaga tgaaatacac agattaccac
    21961 cagaaggtca agagatgctt tttcttttga tggacaaagg catatacaga cgattaggag
    22021 aatctgacat tgtgcataaa gctaatgtct ttattgtgtg tgccacaaca gaagatatac
    22081 attcttctct gcttggaact tttttaagaa gaatccctgt tacaatcaac ctacctgctt
    22141 tacaggatag gtctttaaaa gaaagattat ctcttattaa atacttcttt attatagaat
    22201 caaaatacac caatgcaact ataaaagttc acaaagatgt aattaaatca ttactccttt
    22261 atgattgttt tggtaatata ggtcagctta aatctgacat acaacttatg agtgcaagag
    22321 ccttcttaaa ttacaaaact ggacttaagg ataatataga aatagattta tcccttgttc
    22381 ctgattacat ctatattggt cttttaaaat tgaatgaaaa tcgtagtaat ctaaataaat
    22441 tatcagaact tgattatatg cttttttatg aatttaatgg taataactta gaagttgaat
    22501 atacaaaaga actatctaaa tacaatatag atacatcaaa caatggattt aaatactcta
    22561 cagagattcc ttatctggaa aatgatataa ggagtatgtt tataaattac atggaaaagt
    22621 actctacaaa attactttcg atatcttcag taactcattc tgattataca agtaatgaga
    22681 tttttaaagt aatcaatcca aagatttact atgctgttga acattcttta aaagaggctg
    22741 aaaaaatatc gagaaacaaa tacacaaaac aaacttatat tgctctttca atgcatataa
    22801 gtgcacttat agaaaatata aatcaagaca catataatcc taagtacaat ttatataatg
    22861 ataaaatttt cttagataaa gatttaaata tagctaaaat agttttaagt ataattgaaa
    22921 atgacttaca aacatcttta cctaaagatg aagtaaaatt tatatccatg tttctaaata
    22981 gcatgtatct tgaaccaaac aatcaatctg aaagtatagg agtcataata cttgctcatg
    23041 gaaattcaac agcaagcagt atgtgtgatg tagcaaattc attgcttggt acaaaccatt
    23101 gtaatgcaat tgacatgcct cttgatgtaa aagtaagtac catacttgat aaaactatag
    23161 agttggtaaa agaatgtgac gaaggtaagg gtgtacttct tttaacagat atgggctctc
    23221 ttatagcttt tggagaactt atttcagaaa aaacaaaaat caaaactcgc tcaattgaaa
    23281 tggtatctac tccaatagtt ttagaagcag taagaaaaag tacactacca gaaatgactt
    23341 tggatgaatt agctaattcc ttaagctctt taaatccata tattggacga gcagcaatcg
    23401 attcaacaga aataaactat cctgaaaagt caagagagta tgtaataata actacttgta
    23461 taacaggata tggttcagct atgaaagtag cagactttat aaattcttca cttaaaaata
    23521 ttagtaaata caatattaat ttagttcctc ataatataga aagttttaaa atgtataaga
    23581 ataaatttag taatactaaa attctggcag ttgttggaag tgtagatttt aatgtagcta
    23641 acaccccttt tatacacata gaggaactac taaatggata tggcctagat atgctaaaca
    23701 aaataataga aggtacattc aatgccaata gtattacaaa tataaaagaa acaaatctat
    23761 catacaacag tttaataata aactttatga cccaaaactt agagcttttg gactctgtta
    23821 aattattcaa ctatgtcaat tcttccttat ttacaataat agaattaata gatgaaaact
    23881 taaagagcaa atttaagcta ggatatatac tacattgctc ttttatgata gaaagatgtt
    23941 ttaaaaatac aacttttcca tataataaca ttactgaatt aattagtaaa aatcatgaac
    24001 tatatagttt aatacgtgaa gcctttaagc caacagaagc ttattttaat attttgatac
    24061 cagacgaaga aattgcttat ataatagaca tgattaatga gtatctaaat aaataaaatt
    24121 tatagcactt attttgtgca tattaattaa tatatgaaat ggaggacgag attttgaaag
    24181 gaaaaataaa acagttaaca atacttgcat taatttttat atttataact cctgtatttg
    24241 catttgcaga tactccacca gtaccaaatt cttcaagagc agcactactt atagaccagg
    24301 aaactaaaag aatattattt gaaaaaaaca ttgatgaaaa aatgccatta gcgagtttaa
    24361 gtaaaatgat gaccttttta ttggcaatag aagcagttga taaaaatcaa gttaaagaga
    24421 ctgatatggt gaaaatagac aagtctacag cttcagtagg aggttctact tgtaaactta
    24481 aagatggtga tgaaatatct ctaggtgagc ttatgcaggg tctaatgcta gtatctggaa
    24541 atgatgctgc tatagccata gctaaacata ttggtaaaac tgaaaagaat tttgtaaata
    24601 tgatgaacaa gaaagcagaa gaaataggaa tgattgatac gtattatttt aatccaaatg
    24661 ggcttcctat atatactgac ccagaacata aagaacctcc tattgaaaat atgtcaactg
    24721 ctcacgatat agttacactt ggaaagtata tgtacgacca ttatgaaaat caagttacaa
    24781 gaataaccac tatgcaagta tataatgata ctaaaaagga ttttacacat tataacacaa
    24841 atcctctgct tgtttcagta cctggtgttg atggaataaa gacaggatat acagataatg
    24901 ctggatattg ccttgcattt tctatgatgg tacctaaaga tgctaaaaac gaaagaaatc
    24961 atagattgat aggtgttgta cttggtgatg gtaacaagaa aaatagaatt tcttcttccg
    25021 ctactttatt gaaatatggt aaagataatt tccattctaa aaagatagca cataagggtg
    25081 atattataga gactccttgt gttgatggta ttgatgattt taagataaca gttaaggttg
    25141 ataaagattt gtatggtgtt gtttcagata acgaaaatat caatcctaag gtagtgttta
    25201 aaaatatgaa ttatcctatc cataagggag atattgttgg tgttgtaaag tattataatg
    25261 actctggtaa atttgttgga agtgttgatg taaaaagtga aagtaatata ggatgtattc
    25321 ctttgaagga taagattaag attaaggttg ctaagataaa taaaaaactt gagattaaaa
    25381 attctgtttg ttttaaagca tagtaaagca tattattaaa agggtatgtt aaatttataa
    25441 agactccact ttgtggagtc tttttgtttt ttacaaaaaa ttaaaatagt ggcaacaatt
    25501 gaggatgtga gggagagttg ccactatttt gtatagggta ttatattatg tttttaagct
    25561 agttttacta tcttctatgt ttatataata actcttgtgt gtgaatttaa ttgataatta
    25621 atatgaaaat tatgtgaagt tttaagttag ttgacttaga ctattgtaaa ttttttcaga
    25681 aaaattctgt tcataagtct attagaccac cgaattattt acctataata ttccgatcaa
    25741 aaaatctatt cttttttaaa agtaaggtca tgattattgt acatatataa aaattccgaa
    25801 aattaatcta cacactagta acattaagta taataaattt attttagtaa aactattaaa
    25861 ataacctcat aagaaactat agattaaatc aatcaatcta atctacagtt tcttgattat
    25921 tccttaatat ttataattta cattatttgt ttattttaaa actatctgtt acaaatctag
    25981 tcaatgttga aaataaattc gctctgaata tagtagatga tg
//
LOCUS       DAEPKC010000053        25760 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.053, whole genome shotgun sequence.
ACCESSION   DAEPKC010000053 DAEPKC010000000
VERSION     DAEPKC010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 25760)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25760)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25760
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.053"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(405..1385)
                     /locus_tag="KR294_002220"
     CDS             complement(405..1385)
                     /locus_tag="KR294_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240297.1"
                     /translation="MGDTSRFYESVKNKYPKLKDGTRVHLWPKENIIIGPIYDEEDGY
                     KKSIGNVDSLSWKQIVILAECDGKNTTDDIINILSNRYRNIHNMKEKVMEFFMFYENV
                     YLTFEDDIQTLSSVFEITGNKSYITPLYFTIEIDGDNNTNDYFSEITSLLNCMYEKGC
                     RFIEVIGEDILKNKSMREIFQYMLDHFDLIVVTKDSFTIDRSLIKELDNYRHKVIWKV
                     YSKNDDTRIKLKEDIKITSLIKRGHTVVRGDREKAIKIEDMRFKDTKERFSKYGAEWS
                     HLYISSDGSVKSYSFQKDKRIYLGNIFNNSVEEIFLEMQNKIDKLEIVYQ"
     gene            complement(1549..2421)
                     /locus_tag="KR294_002221"
     CDS             complement(1549..2421)
                     /locus_tag="KR294_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBH0240298.1"
                     /translation="MIIKVSMTVLVLILLYILYKYETQHIETTEYTIFNKKIPKEFDN
                     FKIVQVSDLHNKVFDKNNKVLIDKIESLNPDVIFITGDLVDGENKNFQVALDLIDNLV
                     EKYEVYHIIGNHEQKSLIKKYKHLYKDYFKELYSKKIINMENESVRIYRGNSHLNLYG
                     LIIPLECYPYLFANNKKLELSDNFVEDNLGKVNENEYNILLAHTPFFFEKYAKWGADL
                     VLAGHVHGGIIRIPFVGGVLSPNREFFPKYDWGKYEKDNSTMILNKGLGGSKVLIRLN
                     CKPEIVKITFKYEK"
     gene            complement(2585..3136)
                     /locus_tag="KR294_002222"
     CDS             complement(2585..3136)
                     /locus_tag="KR294_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH0240299.1"
                     /translation="MDNKFPNVGENLRLLRQEMGISLDKASKMTGVSKAMLGQIERGE
                     SSPTVSTLWKISSGFKINFTTLLNENTNTYEVIKKEEVEPIVEQKGNMKLYPIYPFSP
                     QRRFELFIIELEENCTHVSSTHSHVLEEYVLVIEGKLDLNVDGKTYILESGHSIRFDG
                     TLEHIYKNLNKGKTIFHNIEVYR"
     gene            complement(3156..4058)
                     /locus_tag="KR294_002223"
     CDS             complement(3156..4058)
                     /locus_tag="KR294_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HBH0240300.1"
                     /translation="MSKKGRVVKVQHFSVNDGDGIRTTIFLEGCKLKCKWCSNPDSWS
                     NIVKLGVMKDKCVSCNRCIDVCPQNISSLFDRAQINNKCDLCGECIKVCLKDAICIMT
                     EEMSVEEIVEEVEKDFIFFFESNGGITFSGGEPTLQIDFLRELVDIFYDKGINIAIET
                     CGYFDWNKVNDVFEKIDHIFVDIKSMDDNIHKEYTGVSNKIILDNICRLSKLNKSMVI
                     RVPIIYGVNDSEENIRNTALFVKQNVPGGKMELLPYHKFGIDKYKALGLEDYIYEFDD
                     ICNNHMLKLKEIVELTGVKIIEYK"
     gene            complement(4073..6445)
                     /locus_tag="KR294_002224"
     CDS             complement(4073..6445)
                     /locus_tag="KR294_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase/glycerol dehydratase
                     family glycyl radical enzyme"
                     /protein_id="HBH0240301.1"
                     /translation="MSQTNRIEAFRQEYINSKPMICCERARIFTESHKKTEGEAICIR
                     RAKAFLETCKELPIKIFENELIVGTAGKFRRTGILTPEFSWQWVDKEMDTFDKRTQDP
                     YVISKEQIEFIRKEIFPYWKGKSLEEVFLARIPEDTAKILVDTGIIDNDSKWRQAVGE
                     VTPDYQDILFVKGYKGIKEDADKKIKELDISVSENIEKIDFYKSVSIVAQGIMTLAQR
                     YSNLAKEMSKQETDEKRKLELIKISEICMNVPANPPTNFYEAIQFVWFVQLGGILSEN
                     PLALNLGRFDQYMYPYYENDAREGKITESEAQELIEALWIKLSEWVWTISANTANYFA
                     GYNQFQNLTVGGKKRNGTDGTNDISYMCLKATESVKTHQPGLSVRVSQGAPDNFVMAV
                     AKLVKQGTGFPAIHSDSAGAQMLLQDGYDAEDARDWSNCGCVVPHFRKTGQWTSAVNI
                     NFAAALEYAMNEGKSRLTGEKMGLDTKNITEFTSFEELKDEFLKQLAYLVKSSVIGTT
                     VAQQIHKEMVPRPFLSTCVDGCLDKGVDLSKGGAKYNIGPVLTGIGLGVVSNSLAAIK
                     KLVFEDKVTTLEELTKALNNDWEGYEELRKLALDVPKYGNDNDYVDSLAIEVSDFYYT
                     ETRKYKDIFGSKFNSAFMGISNYVPTGKIVGATPCGRKATKPLTEGVSPFVGTDTTSP
                     LAAMKSASKINHDVHTGGTLLNLRLNQDLVETERGLRNLTSMIKSYFALGGFHVQFNT
                     ISNDTLLKAQENPEEYKDLLVRVAGYSTQFVNLSREMQDAIIARNSHSNF"
     gene            complement(6666..7355)
                     /locus_tag="KR294_002225"
     CDS             complement(6666..7355)
                     /locus_tag="KR294_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240302.1"
                     /translation="MKVKRNINRVAIIVALNLSLALMVGCMSPVYDKNLSSSEQISKD
                     SLKEQVEDKKDESIELFNNYSQKINDAKGREEVKKDLSQRFSKAIIDSGYSITDSKSD
                     GSFVVSINGAEKPPEKNIRSLFYSMSEDDKEGKVTIDILCAKEYPEDDKLSESDKYIK
                     FIYNLFKSLTNTNLTEKEIFSMVEEDFNKGVGVVELPYMKDIHVEVNKVKQSTKVLKL
                     SLVYKFDISNH"
     gene            complement(7596..8975)
                     /locus_tag="KR294_002226"
     CDS             complement(7596..8975)
                     /locus_tag="KR294_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBH0240303.1"
                     /translation="MLNFMTELLVVLSIFIQFSIMNGILIYKKDSKKNEKIVFYIVLF
                     LIYIIIQISRLFNGGNYFSNINYLFYILAFIAWGGYYNYFYKMGYIKYSIFFYLFSVY
                     YKCLDAVIYRILFFAITGNVISSKESLLVPHLESIKIQIYSNLIIILIYLIFSFFRKS
                     IKLISQDKRNYVYLLFALLVNTMNMLVNYVLKKLERFGSLHSEGYYFDNFVNPKLVGA
                     SSIFLILLFKEIIKENRLKSQAELIKNKLDMQYAHYLSIQESHMRVKKLYHDINNHIY
                     CIDNLRNNSKEINEYVNNLKDEIKTFKYIYNTGNMILDIIINEKSEICLKKGIKFTCS
                     INFSKVNFVKPIDVSSIFSNILDNAIEACDKIVDENVNKYIRIKGTMTRSFFVLKCEN
                     SKLNQLTFNKNILLTNKMDKFVHGIGIQSIKSSLQKYNGELLFENSIDKFILNIYIPL
                     DQDTDSWGD"
     gene            complement(8969..9682)
                     /gene="rgbR"
                     /locus_tag="KR294_002227"
     CDS             complement(8969..9682)
                     /gene="rgbR"
                     /locus_tag="KR294_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RgbR"
                     /protein_id="HBH0240304.1"
                     /translation="MIKIAVCEDEKETQLLIEDYLENILKDISIEYEIQKYISGEELL
                     ESNLKDIDILLLDIKMEKLNGMDTARKIREVDNEMEIIFVTSLIDYVQEGYEVRAYRY
                     LLKPIELEELKKHVLTCIKDIEINKESHITIKNKSNTYKIYLNEIKYIEVQKKDMLIH
                     TINKNFDIKYSLGKIEKELNPYKFIRCHKSFIVNLRYVENIKPNTAILESGEEVPISR
                     YRYKEVKEKFLKFLGDTIC"
     gene            complement(9932..10492)
                     /locus_tag="KR294_002228"
     CDS             complement(9932..10492)
                     /locus_tag="KR294_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HBH0240305.1"
                     /translation="MSAMEKKIKFKFDWYSSPDKIEKWLEDIEAKGYNLYKINKFGGI
                     FYFHKGSPRKIKYTVDYYYDVENNYFDEHKSNGWNLVFRSIGSFMGTSAWYIWSKEYK
                     DIPPKLYSDSDKKNKVKSILFMNMFIFFMLVVIFIYLLNIEIRNLYSGYGASVTAIVL
                     QIILLILYAVQLYRRLMYYLRLKKFK"
     gene            complement(10588..11391)
                     /gene="zupT"
                     /locus_tag="KR294_002229"
     CDS             complement(10588..11391)
                     /gene="zupT"
                     /locus_tag="KR294_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc transporter ZupT"
                     /protein_id="HBH0240306.1"
                     /translation="MNNVIFAFLITLLAGLSTGIGSCIAFFAKKTNTKFLSISLGFSA
                     GVMIYVSMIEIFPKAQDALTKSMGEKLGSWSTVIAFFIGMAIIAVIDKLIPQEENPHE
                     IKKMENIEEKNIKKNKSLLRTGIFTAMAIAIHNFPEGLATFISALDDVTIAIPIAIAI
                     AIHNIPEGISVSVPVYYATGDKKKAFYYSFLSGMSEPLGAIIGYVLLRNFLNDITLGI
                     VFAIVGGIMVFISLDELLPSAREYGEHHLSIYGLIAGMGVMAISLLLFK"
     gene            complement(11542..12705)
                     /locus_tag="KR294_002230"
     CDS             complement(11542..12705)
                     /locus_tag="KR294_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH0240307.1"
                     /translation="MDIKEITKSYKDYVIKLRREFHENPEKSMEEVRTSKRVKEELDK
                     IGIPYVSAGGTGVIATIKGANPGKTVALRGDMDALQVVECTDVEYKSKNEGLMHACGH
                     DGHTSMLLGAAKVLNDIKDSINGTVKLFFQPGEEVGKGARAMIQDGAMEGVDSVFGIH
                     LWTDVESGTISVEEGPRMASADFFKITVKGRGGHGSLPHQGVDAVLASSAIVMNLQSM
                     VSREVSPLEPLVVSVGVLNSGTRFNVIASEAVLEGTIRLFNPELRKQIPGILERIAKS
                     TAEAYRADAELEYGYLTPAVINDKECSKIATDAAIKLFGEDCITLFEKVTGAEDLAEF
                     MNIAPGALAFVGARNESKGACYPHHHGCFNIDEDALEIGTALYVQYAVDFLNK"
     gene            complement(12765..13952)
                     /locus_tag="KR294_002231"
     CDS             complement(12765..13952)
                     /locus_tag="KR294_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240308.1"
                     /translation="MEAITAFCLVLVSLTIGDIVSAKTKAFVPSVFVSAIIFIVGFWT
                     FFPENIVDLAALGTPLAQLGMLLLITHMGTMMSIKELAGQWKTIVIALAGIVGICVGA
                     LALGTVVFGWDTAVIATPPLTGGLVASIMMADAATAKGLASLSVLAILMYVAQGFAGY
                     PITALMLKKEGKRLLSDFRSGKVTVNTDEEKVKDLPEQKSRFKIIPDLPEKYDTTYMI
                     ILRLGFVAWLAVQFTNLTNEVVSRYVICLIFGVIASELGIVDRKPLNKSGSFGWLMTS
                     LMAFIFAGLAKATPAMLVEMAVPLVGIIIFGVIGMGIFSIIVGKLLGESKEMAFSVSL
                     TSLYGFPPNYILTEEAVKALAETPEEKEFLMDKMLPKMLVGGFTTVTIASVVIAGIFV
                     NLI"
     gene            complement(14315..16015)
                     /locus_tag="KR294_002232"
     CDS             complement(14315..16015)
                     /locus_tag="KR294_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0240309.1"
                     /translation="MIKQFVKYYKPYKKIFTLDLIAAFLFSLCDLVYPMITRNIMDDV
                     VPNKNLRMLVVFAVALILIFIAKAGLNYFMQYWGHVIGVDMQADMRNEVFTHLQRLPN
                     TYFDNNKSGVTMSRIVNDLMDITELAHHGPEDLFISIVMLVGSFFILIDINIPLTLII
                     FAILPFIIWFAIAKKDKMNIAFMKSRVTIGDVNATLENSIAGMKVTKSFCTEKEELNK
                     FVRSNKLFRRARQDSYKVMAEYYSGMNLYMDILEWVVVIAGGYFTYIGKITLGDFAAY
                     ILYVKMFIQPMKKLINFTEQYQNGMTGFKRFIEIMEQDHQKEAKNPIELENVKGDIEI
                     ENISFTYEDKTQVLDNLSLSIKAGKTIALVGPSGGGKTTLCNLLPRFYEFDKGDIKID
                     GKSIKDVSLKSLRKNIGIVQQDVFLFTGTIRDNILCGNPNATDEEMIAAAKKARIHDF
                     VETLPDGYDTYIGERGVKLSGGQKQRISISRIFLKNPPIIILDEATSALDNVTEREIQ
                     ESLEELSKDRTNLVVAHRLTTIKNADEIIVLTDKGIEERGTHEELVNKNGVYSRLHNN
                     "
     gene            complement(16270..16545)
                     /locus_tag="KR294_002233"
     CDS             complement(16270..16545)
                     /locus_tag="KR294_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH0240310.1"
                     /translation="MKKILVACGAGIATSTIVCDRVERLVKENNIQAEVEQCKIAECS
                     TKQEGADLIVSTTILPTTYDIPTIKATGYITGINTTALDKKILNALK"
     gene            complement(16664..17236)
                     /gene="mobB"
                     /locus_tag="KR294_002234"
     CDS             complement(16664..17236)
                     /gene="mobB"
                     /locus_tag="KR294_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-guanine dinucleotide biosynthesis
                     protein B"
                     /protein_id="HBH0240311.1"
                     /translation="MLLLDSFMKGHNFMYNILSVVSYSGVGKTTLIEGIIKELNKKGY
                     RVGVIKHTCHDFDMDEEGKDTYKHRKSGARKVCIISDKRVAYIEELKEKNPLYKMIQL
                     YEDMDLIIIEGYKNYRFKRLEVTRKGKYEDILSNKSDLIGIVSDIEYKLNIEQFNLND
                     YKNISKYIESCIKNEILSISNVEIKNILKE"
     gene            complement(17220..18401)
                     /locus_tag="KR294_002235"
     CDS             complement(17220..18401)
                     /locus_tag="KR294_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin molybdotransferase MoeA"
                     /protein_id="HBH0240312.1"
                     /translation="MIELEDAIKIIEKNVLPINRVKIVNLIDAVNKVVAEDIYSTIDS
                     PPFDRSPYDGYAYNANSENRNLKVIGTLYAGDVFNRVLNKNEAVKIMTGGKIPQGANC
                     VIKKEDVTVIGDMITLNIKLKEYDNYIFKGEDIKKGQLIINKNQNIGYDGIGVLASLG
                     ISKVTVYDDLKVGILNTGTELQDINETLENGKIYDSNRYTLYSRLLKLGIQADTICNC
                     SDDILELEKKVKNMLQSVDFLITTGGVSVGDKDLIPDVFKKIGATELFWKINIKPGGA
                     CYVGTLGEKLLFGLSGNPHAAIVVFDNVIVPVIEYLTYKKGTHHIKAIFKGEFNKFSN
                     KDRFVSGKLYTSEGKLYVELNDKKDAKARLSATLRSNCMIKIKKNETIKENQLVDVVI
                     R"
     gene            complement(18612..19346)
                     /locus_tag="KR294_002236"
     CDS             complement(18612..19346)
                     /locus_tag="KR294_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240313.1"
                     /translation="MKLKRSLVCVTILGIILVGCHKENTKEKNQVASKATQQKTMTKV
                     QNDVNEIMNKDYKYIIKNMGIPYNTFYYIKPKVLKESNTMQDINTSSYMTLVYPKYTG
                     NDELDGSALYVDINENKVVNVETNSFSSQGISVIDAESSIVIEKSDHEKSAVSLENFR
                     HIDLGEYVGVEDSRINEIVGDANYDLTAYNHEGSKVVKSYRLKEDNKILKKEVLTISI
                     VDNKIKSIKTIESDKIVKIIKGTLLE"
     gene            19708..20613
                     /locus_tag="KR294_002237"
     CDS             19708..20613
                     /locus_tag="KR294_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBH0240314.1"
                     /translation="MDFKQLEVFVAVAKHQSFSKAARELFLTQPTVSAHIQNLERELE
                     TVLINRSNKVITLTKSGEILYEHAIYILNNCKRAIYDIKEYSGKIEGIIDIACSSIPE
                     TYILPDFMKSFSMSYPDVKFSISHYDSQYAISEILNERISFGLVGSKINNPQIEYLDL
                     LDDELVLITPSDFKIDNKNNCIDIGELAYLNFIMRKEGSGTRNLILNTLSKNNFPVSK
                     LNVIAHVESNEAIKEMVRLGLGVSFISYISAIDYLNAGKIKCYKIKDVDFTRKFFFIY
                     SKKKTFSPLEDKFLNRLCEYFEIII"
     gene            complement(20773..21615)
                     /locus_tag="KR294_002238"
     CDS             complement(20773..21615)
                     /locus_tag="KR294_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBH0240315.1"
                     /translation="MTTSSKKLETISPDSKITRKDFWKCFRRSLTLDSSWNYERMQNI
                     AYAYMMAPIIRRLYKDDKEKKSKALKRHLEFMSVTPHISTLLVGISGAMEEENAKNKE
                     FDANSINAVKSSLMGPVSGIGDSFFWGTLKLIAAGVGIALASQGNIMGPILFLLIINV
                     PHFIIRYICLDKGFKYGTQFFKDVSGSSIVSKVMEAASMLGLMVIGGMTASNVMLKLS
                     VNVGSGEWAEPIQTYLDQIMPCMLPAMIFGIMYWLLGKKVKTTTILISVMIICIVLAA
                     IGVV"
     gene            complement(21599..22357)
                     /locus_tag="KR294_002239"
     CDS             complement(21599..22357)
                     /locus_tag="KR294_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH0240316.1"
                     /translation="MEFTQVILITLIAFFAYMHSFVGSTMHNRPIVVAPLVGLALGNL
                     HTGIVIGSTLELVFMGAFPVGASNPPDFVSGSIIATAFVILTGQDVSAAVVLAVPIAT
                     LVLLIDNFLMTVVLTWGAHIADRYAEEGNIEGVERVQLLFGIGNKLILAIIVGIGFSL
                     GVPVIEKILSFIPSYVTHGMDVAAGVIPAIGFAMLARMMLNKKTVAFLLLGFILVAYL
                     NITVTGVALFGLAIALIYVNFVGEKEVIVDDNEF"
     gene            complement(22374..22844)
                     /locus_tag="KR294_002240"
     CDS             complement(22374..22844)
                     /locus_tag="KR294_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH0240317.1"
                     /translation="MIKLVRVDHRLIHGQVAFTWTKFLSTDCILIASDDLLKDELRMA
                     GLKMAKPSNVKLVMKSIADSIKALNSGVTDKYNLLILCESVEDVYRLAKEVKAIKSIN
                     LGGTKSDDNRENISKAVHVSKDDIKMIKELDSEGVNVFVQLVPDDDATNVMKLI"
     gene            complement(22844..23587)
                     /locus_tag="KR294_002241"
     CDS             complement(22844..23587)
                     /locus_tag="KR294_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane biogenesis protein"
                     /protein_id="HBH0240318.1"
                     /translation="MKKKGILSVFKSKKPIIAMIHLKGDTPEDIFERAKKEITIFEEN
                     GVDGIMLENYYGNYYDLERILEYVSKANLSIPYGVNCLNVDTMGFELATKYNASYIQV
                     DSVVGHVKPRDEATLEEFFKLQRSKCPAYLIGGVRFKYQPVLSENDVEEDLKIGMTRC
                     DAIAVTENATGQETSMEKIELFRKNLGDFPLVIAAGVTLENAKKQLKLGDMAIIGSYF
                     KDNYKDFGDVSVEHVKTFMDEIKKIREEL"
     gene            complement(23591..24004)
                     /locus_tag="KR294_002242"
     CDS             complement(23591..24004)
                     /locus_tag="KR294_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH0240319.1"
                     /translation="MKKIILASHGDFSKGLLNAVKMIVGDLADCVSSYGLYPGQSASD
                     FALELEKTISEDKECEYIILSDLYGASVCTAMLRLTNLHNVRLFSGMNLNMVLELLTR
                     FSDELTVEDIDQLVEESRRGIQSVTLQIKEEEEVF"
     gene            complement(24030..24614)
                     /locus_tag="KR294_002243"
                     /pseudo
     CDS             complement(24030..24614)
                     /locus_tag="KR294_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896033.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
     gene            complement(24799..25182)
                     /locus_tag="KR294_002244"
     CDS             complement(24799..25182)
                     /locus_tag="KR294_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBH0240320.1"
                     /translation="MKISKLPEAELKVMRYIWEANKVLTSRELVAAMEEKYEWNESTT
                     FTVLKRLERREFLSTEKIGKLTHYNILVKEKKYLRFETKEFLKNIHKNSISSLISALH
                     SKDDEVDEDKLIELEEHFKNLKEKE"
     gene            complement(25287..25664)
                     /locus_tag="KR294_002245"
     CDS             complement(25287..25664)
                     /locus_tag="KR294_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBH0240321.1"
                     /translation="MKEEILIEKLLRAELIVMEYLWKKDTLMPKKEIVKEIKQIYGWH
                     KSTIKILLKRLIDKGYLARDIIKFQSYYKIIIDNEEYYAFKKKVLKSSKSRKIMRSLT
                     TTHKNVSKEKLDSLEEYYKNLKE"
BASE COUNT         8423 a         4554 c         2563 g        10220 t
ORIGIN      
        1 taataaaaca aattaaataa aaaaaaaacc ataaatttta aatttatgga ttaattcttg
       61 taatgataac tctatttgag gatgtgaggg agggttatca ttacaatagg gtattatatt
      121 atggttttta agctagtctt tctacacctc atatgataca tatgctatat gaattttata
      181 tgatttttac ataaatattt tatgaaattt aaatttttta gtcattttga aatttgtaaa
      241 aagttctcta aaaatccaca gcatcataaa cagccaaaat ttaagtaaaa catcataaaa
      301 aaatttgtcc aataatttta acaagtaatc tcacctcatt ataattattg acacaaactt
      361 aaataaacaa tctataaatc ttctataaat cttaaacttt ccccctattg atacacaatt
      421 tctagtttgt caattttatt ttgcatttct aagaaaattt cttcaacaga attgttaaat
      481 atattgccta aatagattct tttatctttt tgaaatgaat aagattttac actaccatca
      541 gaagaaatat ataaatgact ccactctgct ccatattttg aaaacctctc ctttgtatct
      601 ttaaacctca tatcttctat ttttattgct ttttctctgt ctcctcttac tacagtgtga
      661 ccccttttta ttaaactggt tatttttata tcttctttta atttaatacg tgtatcatca
      721 ttttttgaat atactttcca tatcacttta tgacgataat tatctaattc ctttattaag
      781 cttctatcaa tagtaaaact atctttagtt accacaatta aatcaaaatg gtctaacata
      841 tattgaaata tttctctcat acttttattt tttaaaatat cctcaccaat aacctctata
      901 aatctacagc ctttctcata catgcagttc aataaacttg tgatttcaga aaaataatca
      961 tttgtattat tatctccatc tatttctata gtaaagtaca aaggagtaat gtatgattta
     1021 tttcctgtta tctcaaatac acttgatagt gtctgtatat catcttcaaa cgttaagtac
     1081 acattctcat aaaacataaa aaattccata actttttctt tcatattatg gatatttcta
     1141 tatctattgg ataatatatt tattatatcg tcagtagtat ttttcccatc acattcagcc
     1201 agtataacaa tttgcttcca acttaagcta tccacatttc cgatactttt tttatatcca
     1261 tcttcttcgt cataaatagg accaattata atgttttctt ttggccacag atgaacccta
     1321 gttccatctt ttaatttcgg atatttattt tttacagact cataaaatct acttgtatca
     1381 cccatgattc tttactaccc cccatagttt aaatattcta tgctaaaaat agcactttat
     1441 ttttattaat tcaacaatta ttcaaaattg gtcattatat atgtttaaat ggatttaaca
     1501 tcaaccttat ttatatgtta ttgatgttta tatatgttat ataaaatctt atttctcata
     1561 cttaaatgta atcttaacta tctctggttt acaattaagc ctaattaaaa cttttgagcc
     1621 tcctaagcct ttatttaaaa tcatagtgct attatctttt tcatattttc cccagtcata
     1681 cttaggaaag aactctctat ttggagataa tacacctcca acaaaaggta ttcttattat
     1741 acctccatga acatgtcctg ctaaaaccaa atctgctccc cattttgcat atttttcaaa
     1801 gaaaaatggt gtatgtgcta aaagaatgtt atattcattt tcattaactt tacctagatt
     1861 gtcttctaca aaattgtcac ttagttctaa ttttttgtta ttagcaaata aatatggata
     1921 gcattccaat ggtataatta aaccatataa attaagatgg ctattacctc tatatattct
     1981 tacagattca ttttccatat ttattatttt ctttgaatat agttccttaa aataatcctt
     2041 atatagatgt ttatactttt ttattaaaga tttttgttca tgatttccaa ttatatgata
     2101 tacttcatat ttttcaacca aattatctat taaatctaat gcaacttgaa aatttttatt
     2161 ttctccatct actaaatctc ctgttataaa tataacatct gggtttaatg attcaatttt
     2221 atctatcaat accttattat ttttatcaaa caccttatta tgtaaatcac tcacttgaac
     2281 tattttaaag ttatcaaatt cctttggaat ttttttgttg aaaatagtat attctgtcgt
     2341 ttctatatgc tgagtttcat acttatacag aatatacaat aatattaata ctaatactgt
     2401 cattgaaacc tttataatca tattctcttc ctctttattc tattttgtta atattattat
     2461 aatgctttta tgtttttttt aaaacaataa catcatcaca tacatataaa tcttttcgac
     2521 attataaaaa taagttatcc ttttctaaaa ttttcattta ttttagaaaa ggataactat
     2581 aaaattatct ataaacctct atattgtgaa atatagtttt tcctttattt aaatttttat
     2641 atatatgctc taaagttcca tcaaacctaa tagaatgtcc agactctaaa atataagttt
     2701 tcccatccac attaaggtca agtttacctt ctattacgag cacatattct tctaaaacat
     2761 gactatgtgt agatgaaaca tgagtacagt tttcctcaag ctcaattata aaaagttcaa
     2821 accttctttg agggctaaaa gggtatattg gatataactt catgttccct ttttgctcaa
     2881 caataggctc tacttcttct ttctttataa cctcataggt atttgtattt tcatttaata
     2941 gtgtagtaaa atttatttta aatccagatg aaattttcca taaagtagat actgtcggac
     3001 ttgattcacc tctctcaatc tgtccaagca ttgctttact gacacctgtc atctttgaag
     3061 ctttgtctaa acttatgccc atttcttgtc tcaataacct taaattttct cccacattag
     3121 gaaatttatt atccatgtta aaatcctcct gatagctatt tgtattctat gatttttact
     3181 cctgtaagtt ctactatctc ttttaatttt aacatatgat tgttacaaat atcatcaaat
     3241 tcatatatat aatcttcaag ccctaatgcc ttatatttat cgattccaaa tttatgatat
     3301 ggaagtaact ccatcttgcc tcctggaaca ttttgtttga caaataatgc agtatttctt
     3361 atattttctt cactatcatt tactccataa ataattggca ctcttataac catagattta
     3421 ttcaactttg aaagcctaca tatattatct aatataattt tattacttac tcctgtatat
     3481 tctttatgaa tattatcatc catagatttt atatctacaa atatgtggtc tattttctca
     3541 aatacatcat ttaccttatt ccaatcaaaa tatccacaag tttcaattgc aatatttatg
     3601 cctttatcat aaaaaatatc aactaattct cttaaaaaat caatctgaag tgtaggttca
     3661 cctccagaaa aagttatccc tccattagat tcaaagaaaa atataaaatc tttttcaact
     3721 tcctctacta tttcttcaac actcatttct tcggtcatta tacaaatggc atctttaaga
     3781 cataccttga tacactctcc acataaatca catttattat ttatttgcgc tctatcaaat
     3841 agtgaactta tattttgagg acaaacatct atacatctat tacaggatac acatttatct
     3901 ttcataacac ctaattttac tatgttactc caggaatctg gattagaaca ccacttacat
     3961 tttaatttac atccttctaa aaatatagta gtccttattc catctccatc atttactgaa
     4021 aaatgttgta cttttacaac tctacctttt ttactcataa tctacctcat aattaaaaat
     4081 tgctatgtga atttctagct attatagcat cttgcatttc tcttgataaa ttaacaaatt
     4141 gagtactata tccagcaacc ctcactaata aatctttata ttcttctgga ttttcttgag
     4201 cttttaatag agtatcattt gatatcgtat taaattgtac atggaatcct cctaaagcaa
     4261 aatatgattt aatcatagat gttagatttc taagtcctct ttcagtttcc accaaatctt
     4321 gattcagtct taaatttaga agtgttccac cagtatgaac atcatgattt atttttgatg
     4381 cagatttcat tgctgctagt ggacttgttg tatcagtacc aacaaatgga gaaactccct
     4441 ctgtcaaagg ttttgtcgct tttcttccac aaggagttgc acctactatt tttccagttg
     4501 gtacatagtt tgatataccc ataaatgcac tattaaattt agagccaaaa atatccttgt
     4561 attttctagt ttcagtataa taaaaatcag aaacttcaat tgctaatgaa tctacataat
     4621 cattatcatt tccatactta ggaacatcca acgcaagttt tcttaattct tcataacctt
     4681 cccaatcatt atttagtgct tttgttaatt cttctaacgt agtcacctta tcctcaaata
     4741 ctaatttttt tatagctgcc aatgaatttg aaactacacc taaccctata ccagttaata
     4801 caggacctat attatatttt gctcctcctt tacttaaatc aactccctta tccaaacatc
     4861 catctacaca agtagataaa aatggtcttg gtaccatttc tttatgaatt tgttgagcaa
     4921 cagtagttcc tataacagaa ctttttacaa gatatgctaa ttgctttaaa aactcatcct
     4981 taagttcttc aaaagaagta aattctgtga tattttttgt atctaacccc attttttctc
     5041 cagttaatct actcttacct tcattcatag catattctaa agctgctgca aaattgatat
     5101 ttacggctga agtccactgt cctgtttttc taaaatgagg aactacacaa ccacagttac
     5161 tccaatctct agcatcttct gcatcatatc catcttgtaa taacatttgt gcccctgcac
     5221 tatcgctgtg tatagcaggg aaaccagttc cttgttttac caatttagca actgccatta
     5281 cgaaattatc tggtgctcct tgactcactc taacacttaa tcctggttgg tgagttttta
     5341 cactttctgt agcctttaaa cacatatatg agatatcatt cgttccatca gtaccatttc
     5401 tctttttacc accaacagta agattttgga attgattata tcctgcaaag taatttgctg
     5461 tatttgctga tatagtccat acccattctg ataacttaat ccaaagtgct tctatcaatt
     5521 cttgagcttc tgattcagtt attttacctt ctctagcatc attttcataa tatggataca
     5581 tatattggtc aaatctacct aaatttaatg ccaatggatt ttctgataga ataccaccta
     5641 attgaacaaa ccatacaaat tgtattgctt cataaaaatt agttggaggg tttgctggta
     5701 cattcataca tatctctgaa atttttataa gttctaactt tctcttttca tctgtttctt
     5761 gcttactcat ctcttttgca agatttgaat atctttgtgc caatgtcata ataccctgtg
     5821 caactataga aacagatttg taaaaatcta tcttttcaat attttctgaa actgatatat
     5881 ctaattcttt aattttttta tctgcatctt ccttaatccc tttatatcct tttacaaaca
     5941 atatatcttg ataatctggt gttacttcac caactgcctg tctccactta gaatcattat
     6001 ctattattcc tgtatctact aatatcttag ctgtatcttc tgggattctt gctaagaaaa
     6061 cttcttccaa agattttccc ttccaatatg gaaatatttc ttttcttata aattctattt
     6121 gttcttttga tattacatat gggtcttgag ttcttttatc aaaagtatcc atttctttgt
     6181 ctacccattg ccaagaaaac tctggtgtca atatccctgt tcttctaaat tttcctgctg
     6241 tacctactat taattcattt tcaaagattt ttataggaag ttctttacat gtctccaaaa
     6301 aagctttagc tcttcttata cagatagctt ctccctcagt ttttttatgt gattctgtaa
     6361 aaattctagc cctttcacaa catatcatag gtttagaatt aatatattct tgtctaaatg
     6421 cttctattct attagtttga ctcatttaaa atcccccttt ggataatata tactacattt
     6481 ttgtatgtta taacatactt taattatatt atactgtcct ttagcataaa atggaagcaa
     6541 aataacttat tttttttcat ctaccttgaa cacctatata ttaatacttt ttttgttaaa
     6601 tttataaact ctaaaaaaat tttctatgat atattttcta tattgttata gttatttcta
     6661 atatactaat gatttgaaat atcaaatttg tatactagac ttagttttaa aaccttagtt
     6721 gattgtttaa ctttgttaac ttcaacatgt atatccttca tataaggaag ctctacaaca
     6781 cctactccct tattaaagtc ttcttcaacc atagaaaaaa tttctttctc agttaagttc
     6841 gtattagtca atgacttaaa taaattgtat ataaatttaa tatatttatc actctcagat
     6901 aacttatcat cttctggata ctctttagca cagagaatat ctattgttac ttttccttct
     6961 ttatcgtctt cagacataga atagaataaa cttcgaatat ttttttcagg tggtttttca
     7021 gcaccattta tagatactac aaagctacca tctgattttg agtcagtaat actataacca
     7081 ctgtctatta tagctttcga aaatctttga gataaatctt tttttacttc ttctctacct
     7141 ttcgcatcat taatcttttg tgagtaatta ttaaaaagct cgatagattc atctttttta
     7201 tcttcaactt gttctttcaa cgaatcttta ctaatttgtt ctgagctact taagttctta
     7261 tcatatacag gagacataca ccctaccatc aatgctaagc taagatttaa agccacaatg
     7321 attgccactc tatttatatt cctttttact ttcatacaca atcctcccat cacactaacc
     7381 gctctaaagt attacttatt gcactagaat atgtttatat tttctttata ttaaagattt
     7441 attattcaat acatatcacc ttcctatcca attcttataa cttactatta gtaaaattat
     7501 aagctcctta atacagaaat aaggatgtta tcttttgtta ttaaaagata acatccttat
     7561 ttttttgtat caatacatat gtcccaactg gtaacttaat cgccccaact gtcagtatct
     7621 tggtccaatg gtatatatat atttagtata aatttatcga tactattttc aaataataat
     7681 tctccattat atttttgtaa agaagattta atactctgaa tacctattcc atgtacaaac
     7741 ttatccattt tgtttgttaa caatatattt ttattaaaag taagctgatt tagtttacta
     7801 ttttcacatt taagtacaaa aaatgacctt gtcatagttc ctttaattct aatatattta
     7861 ttaacatttt catccactat tttatcacat gcttctattg cattatccaa aatattagaa
     7921 aatatgcttg acacatctat aggttttaca aaatttactt ttgaaaaatt tatagagcaa
     7981 gtaaatttaa ttcctttttt taaacatatt tcactctttt cgttgattat aatgtctaat
     8041 atcatatttc ctgtattata gatatattta aatgttttta tttcatcttt taaattgtta
     8101 acatattcat taatttcttt gctattgttt ctaaggttgt ctatacaata aatgtgatta
     8161 tttatatcgt gatatagttt cttaactcgc atatgagatt cttgaatact taaataatgc
     8221 gcatattgca tatctaactt attttttatt aattcagctt gagattttaa tctattctct
     8281 tttattattt ctttaaacaa tagtataaga aatatactac tagctcctac caattttgga
     8341 ttaacaaaat tatcaaaata gtatccttct gaatgtaatg acccaaaccg ttctaatttt
     8401 tttaatacat aatttacaag catattcatt gtattaacta ataaggcaaa taataaatat
     8461 acataatttc tcttatcttg gctaattaat tttatagact tcctaaaaaa gctaaatata
     8521 agatatataa gaataattat taaattacta tatatctgaa tttttataga ttctaagtga
     8581 ggtactaata aggattcttt agatgaaata acattacctg taattgcaaa aaatagtatt
     8641 ctatatataa cagcatccaa acatttataa tatacactaa atagataaaa gaaaatggaa
     8701 tacttaatat aacccatctt ataaaaataa ttatagtatc ctccccaagc aataaatgct
     8761 aatatataaa ataaatagtt tatattacta aagtaatttc ctccattaaa taatctactt
     8821 atctgaatta taatataaat aagaaacaag acaatataga atactatttt ttcatttttt
     8881 ttactatcct ttttataaat taaaattccg ttcattatag aaaactgtat aaatatagat
     8941 aaaactacta atagctcagt cataaagttt agcatattgt atcaccaaga aattttaaga
     9001 atttctcctt aacttcttta tatctatatc tactaatagg tacctcttct ccactttcca
     9061 gtattgcagt attaggcttt atattttcaa catatcttaa atttactata aaacttttat
     9121 ggcatcttat aaatttatat ggatttaatt ctttttctat tttgcctaaa ctatatttta
     9181 tatcaaaatt cttgtttatt gtgtgtatta gcatatcttt tttttgaact tctatatatt
     9241 ttatttcatt taaataaatc ttatatgtat tagacttatt ttttattgta atatgacttt
     9301 ccttatttat ttcaatatct ttgatacaag ttagcacatg tttttttagt tcttccaact
     9361 ctattggctt tagtaaatac ctataagctc ttacctcata accttcttgc acataatcta
     9421 ttaatgaagt tacaaatatt atttccattt cattgtctac ttctctaatc tttcttgcag
     9481 tatccattcc atttaatttt tccattttta tatcaagaag taatatatct atatctttta
     9541 aattactttc cagtaactct tctccagata tatacttttg tatctcatat tctatactta
     9601 tatcttttaa tatattctca aggtaatctt ctattaaaag ttgtgtttct ttttcatctt
     9661 cacaaactgc tatcttaatc ataaaatgcc tccttacata atttctagtt aatacaatta
     9721 aaatatttat aatatattta aagataattt tgtatatctg atactttagg ataacatttt
     9781 caaattattt ttatcaatac tcaatcccat ataactatta tttgatattt caatttaaag
     9841 acagaaatta ctataattaa aaacagtact tactgataaa agaagatgtc ttaaactatt
     9901 aaaaaaataa ttttaggaca ccttctttta tttatttaaa ctttttaagc cttaaataat
     9961 acattaatct cctatataat tgtactgcat ataaaatcaa caatataatc tgtagtacaa
    10021 tagcagttac agatgctcca taaccactat ataaatttct tatttcaata ttcaataaat
    10081 atataaatat tactactaac ataaagaata taaacatatt cataaataaa attgacttta
    10141 ctttgttttt tttatcagaa tcactatata atttaggagg tatgtctttg tattctttcg
    10201 accatatata ccatgcagat gtacccataa aactaccaat actcctaaat acaagattcc
    10261 agccatttga tttatgttca tcaaaataat tattctctac atcatagtag taatcaacag
    10321 tgtattttat ttttcttgga cttcccttat gaaaataaaa tattcctcca aatttattta
    10381 tcttatataa attatatcct ttagcttcaa tatcttctaa ccatttctct atcttatcag
    10441 gtgaactata ccagtcaaat ttgaatttta ttttcttttc catagcactc attctccaaa
    10501 atgatatttt taaatagctt aaaaatctat ttaaataatt atatcatttt gatactaatt
    10561 ttaggttaca atcatatatt taaaaagcta tttaaatagt aataaactaa tagccataac
    10621 acccattcct gcaatcaatc cataaataga taaatgatgt tccccgtact ctctagctga
    10681 tggcaataat tcatctagtg atatgaatac cataattcct cctacaattg caaatacaat
    10741 tccaagagtt atatcattta aaaaatttct aagaagtaca tatccaataa tcgctcctaa
    10801 aggctcagac ataccagata aaaaggaata ataaaaagct ttctttttat ctcctgtggc
    10861 ataataaact ggtacagata cagatatacc ttctggtata ttgtgtattg caattgcaat
    10921 tgctatcgga atagctattg taacatcatc aagagctgat ataaatgtag ctaatccttc
    10981 aggaaaattg tgaattgcta tagccattgc tgtaaatata cctgttctca aaagagactt
    11041 attttttttg atattctttt cttctatatt ctccattttc tttatttcat gtggattttc
    11101 ttcttgtgga attagcttat caataacagc aatgatagcc atacctataa aaaaagctat
    11161 tacagttgac caacttccta atttctctcc catagatttt gtcaaagcat cttgtgcttt
    11221 aggaaaaatt tctatcatag aaacataaat cataacacca gcagaaaatc ctaagcttat
    11281 agaaagaaac ttagtatttg tttttttagc aaaaaatgct atacaacttc ctataccagt
    11341 agataaacca gccaataatg ttatcaaaaa tgcaaatatt acattattca aataaatcac
    11401 cttcttttta attgatattg attatcattt tctttatgct atcatatata ttttatatag
    11461 tcaatattta taaaaaatat acacaataaa aaagcagaga tataaactta gtctctgctt
    11521 tttctttata gtatattaaa attatttatt taagaaatcc actgcatatt gcacatataa
    11581 agcagttcca atttctagag catcttcatc tatattaaag catccatgat gatgaggata
    11641 acaagcacct tttgactcat ttctagctcc tacaaatgct agtgcaccag gtgctatatt
    11701 cataaactca gctaaatctt ctgctcctgt tactttttca aatagtgtta tacagtcttc
    11761 tccaaatagc ttaattgctg catctgtagc tatctttgaa cattctttgt catttataac
    11821 tgctggtgtt aagtacccat actctaattc agcatctgct ctatatgctt ctgctgtaga
    11881 ttttgctata cgttctaaaa ttccaggaat ttgctttcta agctctggat taaatagcct
    11941 tattgtacct tctaagacag cttcactcgc aattacgtta aatctagttc cagaatttaa
    12001 aactccaaca ctcacaacta atggttccag aggacttact tctctactaa ccatagattg
    12061 tagattcata actattgctg aacttgcaag cactgcatca acaccttgat gaggaagtga
    12121 accatgacca cctctacctt ttacagtaat tttaaagaaa tcagcagaag ccattcttgg
    12181 tccttcttct accgatatgg tcccagattc tacatcagtc caaagatgta ttccaaacac
    12241 actatctaca ccttccatag caccatcttg aatcatagct cttgcacctt taccaacttc
    12301 ttctcctggc tgaaaaaata attttacagt tccattgata ctatccttaa tatcatttaa
    12361 cacttttgct gcccctagaa gcattgatgt gtgaccatca tgaccacaag catgcataag
    12421 tccttcattt ttagatttgt attctacatc agtgcattca acaacttgta gagcatccat
    12481 atcaccccta agtgctacag tctttcctgg attagctcct tttatagttg caattacacc
    12541 tgtacctcca gctgatacat atggtatccc tattttatca agttcttctt taactctctt
    12601 tgatgttctc acttcttcca tacttttctc aggattttca tgaaattccc ttctaagctt
    12661 aattacatag tctttataac tctttgttat ttctttaata tccattccat acctccaagt
    12721 agtacacatt cttcttattt aaaatacttt ttatcactta aatactatat tagatttaca
    12781 aagatacctg ctattactac agaagctatt gtaactgtag taaatcctcc aacaagcatc
    12841 tttggaagca tcttatccat taaaaattct ttttcttctg gtgtttcagc caaagccttt
    12901 actgcctctt cagttaatat atagtttggt ggaaaaccat aaagtgatgt aagcgaaact
    12961 gaaaaagcca tttctttact ttcacctaaa agcttaccta ctataataga gaatattccc
    13021 atacctatta caccaaatat tatgattcct acaagaggaa ctgccatttc aacaagcatt
    13081 gctggtgtag cttttgctaa ccctgcaaat ataaaagcca tcaatgatgt cattaaccat
    13141 ccaaatgaac cagatttatt aagtggtttt ctatcaacta ttccaagttc tgatgctatt
    13201 acaccaaata ttaaacatat aacatatctt gatacaactt catttgtaag atttgtaaat
    13261 tgtactgcta accatgctac aaatcctaat ctaagtatta tcatatatgt cgtatcatat
    13321 ttttctggta agtctggtat tatcttaaat ctgctttttt gttcaggtaa atccttaact
    13381 ttttcttcat ctgtatttac agttactttt ccacttctaa agtctgataa aagtcttttt
    13441 ccttcttttt taagcattaa tgctgtaata ggataacccg caaatccttg tgcaacatac
    13501 atcaaaattg caagtactga taaacttgca agaccttttg ctgtagcagc atctgccatc
    13561 attatagatg caactagccc tccagtaaga ggaggtgtag ctattactgc tgtatcccat
    13621 ccaaatacta ctgtccctaa tgccaaagca cctacacata ttcctactat tcctgccaag
    13681 gctattacta ttgttttcca ttgacctgct aattccttaa tactcatcat agttcccata
    13741 tgagttatta acaaaagcat acctaattga gctaatggtg ttcctaaagc ggctaagtcc
    13801 acaatatttt ctgggaaaaa agtccaaaat cctactataa atataattgc tgatacaaaa
    13861 accgacggaa caaaagcttt agtttttgct gaaactatat ctcctatcgt cagtgatact
    13921 aaaactagac aaaaagctgt tattgcctcc atacaaaatc ccccctcata ataaatatat
    13981 ttttataaaa tgtatgtata gttatccatt attttactac ttttgaaaaa catttcaagt
    14041 caaaattcga tttttttcat aaaattcgat aaattccata aattaaagtt agttttctaa
    14101 attattcttt ttgtaaaaac gttatcccga ccattggcta tttaactcta ttcttacaaa
    14161 gagaattaaa tgtaatttgc aaaaaataaa acataggata cattttattc ataaaacatc
    14221 ttataaatat aaaatgaatt gtctttatga atcttaatat atcctatgtt tgtaagttta
    14281 atgtgtatgt tagctatggt gtaaaatttg tatactagtt attgtgtaac ctactatata
    14341 ctccattttt gtttactagc tcttcatgag tacctctttc ttcaattcct ttatccgtca
    14401 atactatgat ttcatcagca ttttttatag tagtcaatct atgtgcaaca actaaatttg
    14461 ttctatcttt acttaattcc tctaaagact cttgaatttc tctttctgtt acattgtcta
    14521 aagcagatgt agcctcatcc aatattatta ttggaggatt ctttaaaaag attcttgaaa
    14581 ttgaaattct ttgtttttgc ccacctgata attttacgcc tctttctcct atataagtat
    14641 catatccatc tggcaaagtc tctacaaagt catgtattct agctttttta gcagcagcta
    14701 tcatttcttc atctgtggca ttagggttcc cacaaagaat attatctctt atagttcctg
    14761 taaataaaaa tacatcttgt tgaactatac ctatattttt tctcaatgat tttaaactaa
    14821 catcttttat actctttcca tcaattttta tatcaccctt atcaaattca taaaatcttg
    14881 gcaataaatt acataatgta gtctttcctc ctccagaagg tccaactaat gctatagtct
    14941 taccagcttt tatagataaa cttaaattat ccaaaacttg agtcttatct tcatatgtga
    15001 aagatatatt ttctatctca atgtcacctt ttacattttc aagttcaata ggatttttag
    15061 cttctttttg atggtcttgt tccattatct ctatgaatct tttaaaacct gtcataccat
    15121 tttgatattg ctctgtaaag tttattaatt ttttcatagg ttgtataaac atttttacat
    15181 atagtatata agcagcaaaa tcacccaaag taatctttcc tatataagta aaataaccac
    15241 cagctattac aactacccac tctaagatat ccatgtataa attcatacca gagtaatatt
    15301 ctgccattac cttataagaa tcttgtcttg ctcttctaaa taatttattg cttcttacaa
    15361 acttatttaa ctcttctttc tcagtacaaa aagacttagt taccttcata cctgctatac
    15421 tattttctaa agtagcattt acatcaccta tagtaactct actcttcata aaagcaatat
    15481 tcatcttatc ttttttagct attgcaaacc aaattataaa cggtaatata gcaaatatta
    15541 taagcgtaag aggaatattt atatctataa gtataaagaa tgaaccaacc aacattacta
    15601 tagaaatgaa taaatcttca ggcccatgat gtgcaagttc tgttatatcc attaaatcat
    15661 ttactattct agacatagtt actccagatt tgttattatc aaaatacgta tttggaagtc
    15721 tttgtaagtg tgtaaatacc tcatttctca tatcagcttg catatctaca ccaataacat
    15781 gtccccaata ctgcataaaa tagttaagcc ctgcttttgc tataaatata agtataagtg
    15841 ctactgcaaa aactactaac attcttaagt ttttatttgg aacaacgtca tccattatat
    15901 ttctagttat cataggataa actaaatcac ataaggaaaa tagaaaagct gctataaggt
    15961 ctagtgtaaa aattttctta tatggcttat aatatttgac aaattgtttt atcataagta
    16021 ttaaatccct cctttattag tacttctatt agtacttcta aaaaataccc ataaattagt
    16081 ataacataac aataacttta aatcttttat aaacttacaa agtaataaca atctttttca
    16141 taaaattgaa gatttatatc atatagttgt atacttgaaa caacataaaa agagctatat
    16201 ctctatattt aaaattttat aaagatacaa ctctatattt aatactaaat tttttttata
    16261 aatacaaaac tacttcaatg catttaatat ctttttatct aatgctgttg tatttatacc
    16321 tgttatatat cctgttgcct ttattgtagg tatatcataa gttgttggta gtatagtagt
    16381 agatacgatt aaatcagcac cttcttgttt tgttgaacat tcagcaattt tacattgctc
    16441 aacttctgct tgtatattat tttctttaac caatctttct actctgtcac aaactattgt
    16501 tgatgttgcg attcctgctc cacaggctac taatattttt ttcatatatt gtcctcctac
    16561 aatttcttta atattttata actcaaaata aaattgataa atttcttata tctttattta
    16621 tataaataat tatatcattt tatataagaa gaacatctta aaattattct tttaatatgt
    16681 tttttatttc aacattgctt atacttaaaa tttcattttt tatacaagac tctatgtact
    16741 ttgatatatt tttataatca tttaaattaa actgttcaat attcaattta tattctatat
    16801 cactaacaat acctatcaaa tcagacttat tagataaaat atcctcatac ttaccttttc
    16861 tagttacttc cagtctttta aatctataat ttttatatcc ttctatgata atcaagtcca
    16921 tatcttcata taattgaatc attttatata atggattctt ctcttttagt tcttcaatat
    16981 atgctactcg tttatctgat attatacaga cttttctcgc cccagatttt ctatgtttat
    17041 aagtatcttt tccttcctca tccatatcaa aatcatgaca ggtatgttta ataactccaa
    17101 cacgataccc ttttttattt aattctttta ttatgccttc aatcaacgta gttttaccta
    17161 ctcctgaata tgagacaact gacaatatat tatacataaa attgtgtcct ttcataaaac
    17221 tatctaataa caacatccac taattgattt tcttttattg tctcattctt tttaatctta
    17281 atcatacaat tacttcttag agttgcagat agtctagctt ttgcatcttt cttatcattt
    17341 agctctacat acaatttacc ttcacttgta tatagttttc cacttacaaa tctatcttta
    17401 tttgaaaatt tattaaattc tcctttaaat atagctttta tatgatgtgt tcccttctta
    17461 tatgttaaat actcaataac aggaactatc acattatcaa ataccactat tgctgcatgt
    17521 ggattaccag aaagaccaaa taatagcttt tctcccaatg tacctacata acaagctcca
    17581 ccaggtttaa tgtttatctt ccaaaataat tctgttgccc ctattttttt gaatacatct
    17641 ggaattaaat ctttatctcc aacagaaaca ccacctgtgg taattaaaaa atctacactc
    17701 tgtaacatat tctttacctt tttttctaac tccaatatat catcagaaca attgcatatt
    17761 gtatctgctt gtattccaag ttttaataat cttgaatata aggtatatct attactatcg
    17821 tatattttac cattctctaa agtctcattt atatcttgta gttctgtacc tgtattcaaa
    17881 attccaactt ttaaatcatc ataaacagtt actttggata ttccaagact tgctaatact
    17941 ccaataccat catatcctat attctgattt ttattaataa tcaattgccc cttttttata
    18001 tcctcaccct taaatatgta attatcgtat tcctttaatt ttatatttaa agttatcata
    18061 tcacctataa ctgttacatc ttcttttttt attacacaat ttgcaccctg tggtatcttt
    18121 ccaccagtca ttatcttcac tgcttcattt ttatttaata ccctattaaa tacatctcct
    18181 gcatacaaag tccctataac ctttaaattt ctattttcag aatttgcatt atatgcataa
    18241 ccatcatagg gtgacctatc aaatggagga ctatcaattg ttgaatatat atcttctgca
    18301 actaccttat ttactgcatc tataagattt actatcttga ccctgtttat tggtaaaaca
    18361 tttttttcaa taatttttat ggcatcttct aattctatca ttttaaatac tccccaatat
    18421 attttttatt taagatattt ctatgtaata tattatagat tataaaagtt ggaaatactt
    18481 ttatcttata tttaattata actaatagtt atctataagt gcagttcaaa ttttataaat
    18541 ctaataaaaa aactgttccc agctagaaat ttccttctat cttgaaacag catcatatgc
    18601 tttagaatat tttattctaa taaagttcct tttattattt ttacaatttt atcactttca
    18661 atagttttta tagattttat tttgttatcc acaatactta ttgtaagtac ctcttttttt
    18721 aatattttgt tatcttcttt caatctataa ctcttaacta ctttactgcc ttcatgatta
    18781 tatgctgtta aatcataatt cgcatctcct acaatttcat ttattctgga atcttcaaca
    18841 ccaacatact ctcccaggtc aatatgtcta aaattttcta gtgatacagc cgatttttca
    18901 tggtcacttt tttcaatcac tatactagat tcagcatcaa tgactgatat accttgtgat
    18961 gagaaagaat tggtttcaac attgacaact ttattttcgt taatatcaac atataaagca
    19021 cttccatcta gttcatcatt tccagtatat tttggataaa ctaatgtcat ataacttgat
    19081 gtatttatat cttgcattgt atttgattct tttaaaactt taggttttat ataataaaat
    19141 gtattataag gtatacccat attctttata atgtacttat aatctttatt cataatttca
    19201 ttaacatcat tttgaacttt tgtcatagtt ttttgctgtg ttgctttact tgctacttga
    19261 tttttctctt tagtattttc tttatgacat ccaacaagta taatacctaa aatagttaca
    19321 caaactaatg acctttttaa cttcataaat caatcctcct ttcttaaatt ttatagtatt
    19381 tatctatatc tcaatttaca gttatctctt ttttcaataa ttatatttat tatattataa
    19441 aataattata taatatttat ttgaatttaa taagattaag aagctaattg taatttttct
    19501 gtaataaaaa acactttaaa gttgaatttt gaaaattcaa tttacgatat ttttattgta
    19561 agtaccttac aacattatac caaattattc ctaaacaatc aaaaactcca tgaatattta
    19621 aaggttttct attttaaaaa tcacctttga ctattaattt atcaaatatg ttataatagt
    19681 tttagataat ttaaggagga ttaaataatg gattttaaac aacttgaagt atttgttgct
    19741 gttgcaaaac atcagagttt ttcaaaggct gcaagagaac tttttttaac tcaacctact
    19801 gtaagcgcac acatacagaa tttagagaga gagctagaaa ctgttcttat aaatagaagc
    19861 aacaaagtta ttacactcac aaaatctggt gaaattcttt atgaacatgc tatatatata
    19921 ttgaataatt gcaaacgtgc aatttatgat ataaaagaat attcaggaaa aatagaaggt
    19981 attatagata tagcatgtag ttccatacct gaaacttata ttttacctga ttttatgaag
    20041 agtttttcta tgagttatcc agatgtaaaa ttttccataa gccattatga ttctcaatat
    20101 gctatatcag aaattttaaa tgaacgaata agctttggat tagttggttc taaaatcaat
    20161 aatcctcaaa tagagtacct agacttatta gatgatgaac ttgttcttat cactccttca
    20221 gattttaaaa ttgataataa aaataattgt atcgatatag gagaattggc ttatctaaat
    20281 tttattatga gaaaagaagg gtcaggtaca agaaacttaa tactaaacac acttagtaaa
    20341 aataactttc cagtaagtaa attaaatgta atcgctcatg tagaatcaaa tgaggctatt
    20401 aaggaaatgg ttagattagg tcttggagtg tcctttatat cgtacatttc agctatcgat
    20461 tatctcaatg caggtaaaat aaaatgttat aaaataaagg atgttgattt tactagaaag
    20521 tttttcttca tttactctaa aaagaaaact ttttccccat tagaagataa atttctaaac
    20581 agattatgtg agtatttcga aattataata taataacttt aataaagtag tgcttaattt
    20641 tgagtttata actaattaat aagctaatta taactatcac ataaatgctt ataaattatt
    20701 atgaaccatc tttctttttt atttaattta gtcaaaaaat ccctcgttca aatgaacttg
    20761 ggattttttt atttatacta ctccaatagc agccaatact atacaaataa tcataactga
    20821 aattaatatc gtagttgtct ttaccttttt tcctaataac caatacataa taccgaatat
    20881 catagctgga agcatacatg gcattatttg gtctaagtaa gtttgaatag gctctgccca
    20941 ttctccacta cctacattaa cactaagttt taacattaca ttagatgcag tcatacctcc
    21001 aattaccata agccctaaca ttgaagctgc ttccataact tttgaaacta tacttgaacc
    21061 actcacatct ttaaagaatt gagttccata cttaaatcct ttatctagac atatatagcg
    21121 tataataaaa tgaggaacat ttattattaa aaggaataaa atcggtccca ttatgttacc
    21181 ctgagaagct aaagctatac caaccccagc tgctataagc tttaatgttc cccagaaaaa
    21241 tgaatctcct atcccagaaa ctggacccat taaacttgat ttaacagcat ttatactatt
    21301 agcatcaaat tctttattct ttgcattttc ttcttccata gctccagata tacctaccaa
    21361 aagagtactt atatgaggag taactgacat aaattctaaa tgtcttttta aagccttaga
    21421 tttcttttct ttatcatctt tatataatct acggattatt ggtgccatca tgtatgcata
    21481 tgctatattt tgcatacgtt cgtagttcca agatgaatct aatgtcaatg accttctaaa
    21541 acatttccaa aagtctttcc tcgttatttt actatctggt gaaattgtct ctaacttctt
    21601 agaactcgtt gtcatctact attacctcct tctctcctac aaagttaaca tatattaaag
    21661 ctattgctaa tccaaacaat gcaactcctg ttactgttat gtttaggtaa gcaaccaata
    21721 taaatcctaa taataaaaat gctactgttt tcttattaag catcattcta gctaacatgg
    21781 caaaacctat tgctggaatc acgcctgctg caacatccat tccatgagtt acatatgatg
    21841 gtataaatga aagtattttt tctattactg gaacacctaa tgaaaatcct atacctacta
    21901 ttattgctaa tattaattta tttcctatac caaataataa ttgcacacgt tctacgcctt
    21961 caatattccc ctcttctgca taacggtcag caatatgagc tccccatgta agtactactg
    22021 tcattaagaa gttatctata agcaatacta gagttgctat aggaactgca agtacaactg
    22081 ctgctgatac atcttgaccc gttaatatta caaacgctgt ggcaataata gaaccagaca
    22141 caaaatcagg aggattactt gccccaacag gaaatgcacc cataaatact aattctaatg
    22201 ttgaacctat tactatacct gtatgaagat tacctagtgc taaaccaaca agtggtgcaa
    22261 caactatagg tctattatgc attgtagaac ctacaaaact atgcatatat gcaaagaatg
    22321 caattagagt tatcaaaata acttgtgtaa attccatttt catcccccta aaattatatt
    22381 aatttcatta catttgtagc atcatcatca ggaactaatt gtacaaatac atttacgcct
    22441 tctgaatcta actctttaat catctttata tcatcttttg atacatgcac tgctttagat
    22501 atattttcac gattatcatc tgattttgtt ccaccaaggt ttatagattt aatagctttt
    22561 acctctttag caagtctata aacatcttct acagattcac aaagtatcaa taagttgtat
    22621 ttatcagtaa cacctgagtt aagtgctttt atagaatctg ctatgctttt cattactaac
    22681 ttaacattag atggtttagc cattttaagt cctgccattc tcaattcatc ttttaataag
    22741 tcatcacttg ctatcaatat acagtctgtg cttaaaaact ttgtccatgt aaatgctact
    22801 tgtccatgta taagtctgtg gtctactctt actaatttaa tcattataat tcctccctaa
    22861 tttttttgat ttcatccatg aatgttttta cgtgttctac actaacatcc ccaaaatctt
    22921 tgtaattatc tttaaagtaa cttcctatta ttgccatatc tcctaattta agctgttttt
    22981 ttgcattttc taatgtaact ccagcagcta taaccaatgg gaagtctcct aaatttttac
    23041 gaaacagttc tattttttcc attgatgttt cttgacctgt agcattttct gtaactgcta
    23101 tagcatcaca tcttgtcatt cctattttta aatcttcttc aacatcattt tctgataata
    23161 ctggctgata tttaaaacgt acgcctccaa ttaaatacgc tgggcatttt gaacgttgta
    23221 atttaaaaaa ctcttctaaa gtagcttcat ctctaggttt aacatgacct actacagaat
    23281 caacctgtat ataactagca ttatattttg ttgccagttc aaatcccata gtatcaacat
    23341 ttaaacagtt tactccatat ggtattgata aattagcttt tgatacatat tcaagtattc
    23401 tttctaaatc ataataatta ccatagtaat tttctaacat tattccatct acaccatttt
    23461 cttcaaagat tgtaatctct tttttagctc tttcaaagat atcttctgga gtatctcctt
    23521 ttaagtgtat cattgctata attggttttt tacttttaaa tactgataat attccctttt
    23581 ttttcataaa ctaaaatacc tcttcttctt ctttaatttg taatgtcacg ctttgtattc
    23641 ctcttctaga ttcttccact aattggtcta tatcttcaac ggttaattca tcagaaaacc
    23701 ttgtaagaag ttctaatacc atattcaaat tcattccaga aaataaccta acattatgta
    23761 gattagttaa tcttaacatt gctgtacata cacttgctcc atataagtca gataaaatta
    23821 tatattcaca ttctttatct tctgatattg ttttttctaa ttctaaagca aaatctgaag
    23881 cactttgtcc agggtacaaa ccatacgaac tgacacaatc tgctaaatct cctactatca
    23941 tttttactgc atttaaaagc ccttttgaaa agtctccatg agatgctaat attatctttt
    24001 tcatactcat cctcctacta aattatagat tatatttctg ctgatactgc atatttgtac
    24061 ttatcacttc ttataaattg ctcattgtaa tataagacat cattattttc tgtatacacc
    24121 gattgtctta ctttcaatag tggcatatta cttgcacatt taagatggtc agaatattct
    24181 ttgtttgaat gttttacttc aaatatattt tctactcgtt taggtaatgt gcttatatta
    24241 ttagatataa cctccattaa agatttatct tctaattctt cttttaataa aaacatgtaa
    24301 tctattctaa aatagtcaac ttcaaaaata acaggtactt catctattaa tctaagtctt
    24361 ttaatacata ttaccttctc ttctagttca atacttaaag cttcagctac ttgcttatct
    24421 gcttttttta ttaaaacaga gattattttg gtacttggtt ttgcattaat acgatgacaa
    24481 gaattagtaa aactatttcc tgcacatgtt gcttctattc tctctggtat tgttacataa
    24541 gtccctttac cacgtttttt acataatata tcttctttta caagttcatt aagtgcattt
    24601 ctcacagaaa ttcttatatt ttatttatgt ttatttatat ttatttatgt ttttatgagt
    24661 acatttattt acaacctatc taaaacaatt tctttattct attttattta tatttcttta
    24721 tttgtatttt attttattaa actgtcatgg tggcaaaaaa ggtggcaaaa ataatttgcc
    24781 acctaaaata atctttattt attctttctc ttttaaattt ttaaaatgtt cttcgagttc
    24841 aattaattta tcttcatcca cttcatcatc tttactatgt aacgctgata ttaaacttga
    24901 aattgaattc ttatgtatgt tcttcaaaaa ttctttcgtt tcaaacctta gatatttttt
    24961 ctcttttact agtatattgt aatgtgtaag tttgcctatt ttctctgtgc ttaaaaattc
    25021 tcttcgctct aaccttttta aaactgtaaa tgtcgttgat tcattccatt catatttttc
    25081 ttccattgca gcaactaatt ccctagaagt taataccttg ttagcttccc aaatatatct
    25141 cataactttt aattccgctt ctggtaattt actaattttc atagtctaca cccctttacc
    25201 gatttatgta tatgttaaat tctatatcaa taaagtttta caaacaagag aattaaggta
    25261 aataattcca tccaattttt accatatcat tcttttaagt ttttatagta ctcttctaat
    25321 gagtctaact tctctttact tacattttta tgcgtagtgg taagtgaacg cattattttt
    25381 ctacttttac tagattttag tacctttttc ttaaaagcat aatattcttc attatctatt
    25441 attattttat aataagattg aaattttata atatccctag ccaaataacc tttgtcaatt
    25501 agccttttta gtagtatttt tattgtactt ttatgccatc cataaatctg ttttatttct
    25561 tttacaattt cttttttagg cattagagtg tcctttttcc ataaatactc cattactatt
    25621 aattctgctc ttaataattt ttctattaat atttcttctt tcaatttatg tcacttcctt
    25681 aaattcgtct aacttaaatt aataatagga gctttttaag acaaaaacta gaggtaagtt
    25741 ttaccaaata ttctacatat
//
LOCUS       DAEPKC010000054        25299 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.054, whole genome shotgun sequence.
ACCESSION   DAEPKC010000054 DAEPKC010000000
VERSION     DAEPKC010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 25299)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25299)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25299
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.054"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            173..514
                     /locus_tag="KR294_002246"
     CDS             173..514
                     /locus_tag="KR294_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family transcriptional regulator"
                     /protein_id="HBH0240322.1"
                     /translation="MKEENFINVEYEDKRFSINSKEVLYIEKQEYEVKIYTESGNYEV
                     GENAPCIRKLLKEENFFKCSNSYIVNLDKCEFYLSNNCIFVNNNFIRILGSERKKKLK
                     KKLEKLYDYED"
     gene            665..1078
                     /locus_tag="KR294_002247"
     CDS             665..1078
                     /locus_tag="KR294_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1653 domain-containing protein"
                     /protein_id="HBH0240323.1"
                     /translation="MLELKNNLGISERKLKYPCIYKHFKGKYYATMGLSKAIDHIENI
                     CEIYGKENLIQNRNKYKLVIRHTEREEDIYVYRDLDGNFYHKKEEDTNDLVLYKTLYD
                     DTGIFARPLDMFLEKVDTDKYVNSIQEYRFEEVYK"
     gene            1280..1921
                     /locus_tag="KR294_002248"
     CDS             1280..1921
                     /locus_tag="KR294_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBH0240324.1"
                     /translation="MGNTFYIVRHGQTDWNILGKTQGHGNSDLTPQGIEQAKELSEDI
                     GKYSIDYIFSSDLGRAMQTAQILGDKLNIEVQKTEALREMGFGVWEGLLIKEIQKDYS
                     DIYATWRNEPHLVNIPEGETLKIIKERVDAFIKELNEKYDNKNIILVTHSITLRVMLL
                     SFLESGMENIYRIKQDNTALNIVEFKDYGPVIVKMNDTSHIKNHVKINNSALE"
     gene            1945..3198
                     /locus_tag="KR294_002249"
     CDS             1945..3198
                     /locus_tag="KR294_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBH0240325.1"
                     /translation="MSKVIVVGGGASGMMAALSASKNNNEVILVERNGELGRKLRATG
                     GGRCNFTNNREIEDFFDKVVSNKKFLYSSFYTFTNKDLISYFESRNLEYKIEEENDHK
                     VYTKNDKSIEVIEVLNKDLLNHNVKIMYNKKVIDIITEEIALKDDSNKDKSKYLIKGI
                     ILDNGDKILGDKVIISTGGVSYSKTGSDGSMYKILKKHGHTLNKLYPALVPLTIEEKW
                     IKDLQGISMKNVEISCKIKKRKISKSGDMLFAHFGITGPCVLIMSSYINKIIEKEKVE
                     LNIDFLPNLSTDEISSIIRAFPNKNVLNNLKQILPQNFLKEIFSLLSLVDKKASDLSK
                     ADEIRIIEYIKNMKLTCNGTTGINTGMVTSGGISVKEINSSTMESKLVKNLFFTGEVI
                     DIDAETGGYNLQIAFSTGYLAGISV"
     gene            3244..3894
                     /locus_tag="KR294_002250"
     CDS             3244..3894
                     /locus_tag="KR294_002250"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HBH0240326.1"
                     /translation="MGNLVIAVDGPAGAGKSTIAKIVAKKLNINYIDTGAMYRAVTYK
                     CLKSGIDVNNEKEVIQIAENSDIDFKDNNIYLDKEVINEEIRTIEVSNNVSNVAKIKE
                     VRQLMVEVQRKIGMKNSVILDGRDIGSYVFPDADYKFFLVATPEERGNRRYKELCNKG
                     YNTTLEEVIEDIIRRDEIDSNREFAPLVKANDALEIDTTGKTIEEVVEEVVSKINL"
     gene            3945..4541
                     /locus_tag="KR294_002251"
     CDS             3945..4541
                     /locus_tag="KR294_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HBH0240327.1"
                     /translation="MNFYRFVINIFKGFSKIFFKYEVIGAENIPDRGNIVIASNHKSN
                     LDPIFLAAAIENREIAAIAKKELFKVKPLGFILKKLHVMPINREKPDVSTIKTILRSV
                     RDGYVLGIFPEGTRIKGDSFGKAKAGLSVFTIKSKSKVVPVSIISKYKLFSKVIVYIG
                     EPISFEEHFKEKLSNDDHERISQEILEVIKQNYFKYSK"
     gene            4554..5393
                     /locus_tag="KR294_002252"
     CDS             4554..5393
                     /locus_tag="KR294_002252"
                     /EC_number="1.17.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-3-methylbut-2-enyl diphosphate
                     reductase"
                     /protein_id="HBH0240328.1"
                     /translation="MNIKIAKNAGFCFGVKRAMKMAWDEVEKNDSGIYALGPLIHNKQ
                     AVAKYEEKGLKTVNEIDTIPNHENMIIRSHGVPENIYKEAKDKKLKIVDTTCPFVKKI
                     HTVVSEYHNKGYEIIVIGDMKHPEVIGINGWCENSAIIIKTLEQMENMEFDNSKRYCL
                     VAQTTINPELYISIVNKLSDKLEEIVFNDTICSATKTRQESAKELAKKVDCMIVIGGK
                     HSSNTQKLVKVCEDLVPTFAIETKDELDVNTLKKYKNLGITAGASTPNWIIEEVVTFL
                     ENL"
     gene            5638..6792
                     /locus_tag="KR294_002253"
     CDS             5638..6792
                     /locus_tag="KR294_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenic efflux protein"
                     /protein_id="HBH0240329.1"
                     /translation="MEMLISASEEAFLHVGSMIGFFILLFGYINYKTSGNFTNIISKN
                     RKFQPLIGALIGAIPGCGGSLAIMPLYINGKLSFGAIIASLIASMGDAAFVLISSNIK
                     MYFFVTIVSTITGIITGQLVDYFKLEEKLGLKNRRKSDKYDISKNNPKENKEQHNHDE
                     IILDTLAKSHGNTNRLAFIITHGKGYKIYIGIIVIGFIFMSLAHSGLNLPIIEKLHSL
                     EEVIAVIGILFSIIYMWCFKKVFKNSNQKEEENKKISLREMLIHSVGEISFVITWIFI
                     AYLIYDLIILILGGDEYLVKLVLSTGVISVFIGAGLGLIPGCGIQIVLMSFYLKGTIP
                     LGAVIANSISQDGDALFPLLAMDKKSSLWAMIITTIPAILVGMIVYAFLG"
     gene            7098..7274
                     /locus_tag="KR294_002254"
                     /pseudo
     CDS             7098..7274
                     /locus_tag="KR294_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728625.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
     gene            7923..9041
                     /locus_tag="KR294_002255"
     CDS             7923..9041
                     /locus_tag="KR294_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBH0240330.1"
                     /translation="MIVVEKAYKFRMYPNKKQQELINKTFGCCRFVYNKYLAKRIDVY
                     KKHKETFTYKQCSSDLTNLKKELKWLKEPDKFSLQNALRDLDNAYKKFFKEKAGFPKF
                     KSKKINRFSYKTNFTNGNIMYCGQHIKLPKLGMVKVRDKQVPQGRILNATISKEPSGR
                     YYVSLCCTDVDIGAFENTNNHIGLDLGIKEFCISSCGDFIENPKYLKKSLNKLAKLQR
                     ELSRKTIGSLNRNKARLKVARFQEHIANQRKDFLQKLSTKLIKENDIICIEDLQVKNM
                     IRNRKLSRLISDVSWSEFIRQLEYKANWHGRQIVKVGKFFASSQICNKCGYKNEEVKD
                     LNIREWICPSCNETHDRDINASINILKEGLRLITIQNK"
     gene            9174..10679
                     /gene="ade"
                     /locus_tag="KR294_002256"
     CDS             9174..10679
                     /gene="ade"
                     /locus_tag="KR294_002256"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HBH0240331.1"
                     /translation="MSPGFIDAHMHIESTMVMPIELSKKLLKSGTTTIIADPHELVNV
                     KGVSAIDFLLESTKDIPLNVYIMVPSSVPATSFETNGVGKFSAKDMESYVNNPRILGL
                     GEVMCFNDVINSENEILDKLELFKNKVVDGHAPNINGKSLQTYVCAGIENDHECITFD
                     EVYEKLRAGLKILIREGSAAKNLKSIVSGMLKHNLPIEEFMFCTDDKHLDDIEKQGHI
                     RWNIKCAIDLGMEPVRAIKVATYNSAKAYGLRKIGAIGAGYKADIVVLNDLDKMEVDS
                     VYKDGNLVNEEMFSNYNYEIKDKELLNTVKFKYINKEKIQLKVSEKNYVMEIVPYQIL
                     TNKVYESLPCADGYFVPNKEYSKLCVVERHRMTGNVAVAPLKGFGIKNGAIATTVAHD
                     SHNIIVAGDNDDDILVAINYLKEIQGGYVIVSNGKVLAHLSLQVAGLISTFTAEEVQE
                     ITDNMLEIARKMGVPEYVDPFITLSFMALPVVPQIRLTDLGLFDVEEFKFI"
     gene            11031..11495
                     /gene="bcp"
                     /locus_tag="KR294_002257"
     CDS             11031..11495
                     /gene="bcp"
                     /locus_tag="KR294_002257"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002586316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-dependent thiol peroxidase"
                     /protein_id="HBH0240332.1"
                     /translation="MLSIGTKAPEFTLEDKDGNKVSMSDFKGKKVVVYFYPKDNTPGC
                     TRQACAFRNAYDGFKKEDIQVIGISKDSIKSHQKFAEKHELPFILLSDPDLVAIKAFD
                     VWKEKKMYGKTALGVVRATYIIDENGIIEKVFEKAKPDTNAQEILEYLEKQE"
     gene            11505..12248
                     /gene="yaaA"
                     /locus_tag="KR294_002258"
     CDS             11505..12248
                     /gene="yaaA"
                     /locus_tag="KR294_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HBH0240333.1"
                     /translation="MIIMLSPAKNMKNIEVFDRDLSLPCFIDNTKEIVENIKTFGIED
                     FKNKMKINEKLAVLNKNRFESIKFDRLGNPAILTYDGIQYKNIEAENFTRKDEEFANS
                     CIRIISGLYGVVKPYDSIYEYRLEMQTKLRVGEFKNLYEYWGNRIYKELIKEKTAIVN
                     LSSNEYSKSIEKFIKDSDTYITCTFKVNKNGILKVESTQAKKARGMMTKYIVKNRIRD
                     IEELKKFNLEGYKYKENLSNNSEYIFVKE"
     gene            12376..15033
                     /locus_tag="KR294_002259"
     CDS             12376..15033
                     /locus_tag="KR294_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBH0240334.1"
                     /translation="MENHKQMPWHSRATHEILESLDSSEEGLTDTEAEKRLKENGLNE
                     LRKKPPRTTLQMLWSQITDAMVMILIGAAILSLIFGEFTEAFVILIIVTVNAVIGIVQ
                     EKKAESSLEALKNMNSPTARVMRDGEENVIPASNLVVGDIVFLEDGAMVPADLRLIET
                     SSLKIQEASLTGESVPSEKDADTILPKECVLGDRSNMAYTSSIVTYGRGVGVVVATGM
                     DTEVGNIAHLLDSQDDFDTPIKRKLNTVGKTLSVIGIIVCVVIFAIGAFYQRPLLPMF
                     MIAISLAISIIPEGLPATATIVMALGVQRMAKRNALIRKLPAVETLGGATVICCDKTG
                     TLTLNKMTVTHIAVNGDFESGKVTSIDTASEKHPLVYKEIVYAGALCNDACINPDKTD
                     EILGDPTEGALIFMAKKFGIDQEALEEEYPRVFEQPFDSDRKCMTTVHNIDEKIIAYT
                     KGAVDEILDLCTKILTSKGERNITEVDKKNIHELCLNMSKDALRVLGFAKREISSIPK
                     EDSENIEYDLTFIGMVGMIDPPRTEVIDAVSTCKEAGIRTIMITGDHKVTATTIAHEL
                     GIWSEENTVISGDELDNLSDDELDEAVKNTTVFARVSPFDKLRIIQSLKRIGEVPAMT
                     GDGVNDSPALKSADIGIAMGISGTDVAKDSSDMILMDDSFTTIAYAIKEGRRVYRNIQ
                     KVIQFLLVGNIAEILTLFVAILLNWDTPLLAVHILWVNLATATLPALALGVDPPSRNI
                     MKHQPVKSTTLFEKNLIQRVVTQGIFVAIMTILAYKIGLNIENHSVGQTMAFCVLAFS
                     QMLRAFSQRSNTDSMFNRNNGKNPFLLISFLTSAFLIAVILFAPVFRNAFNLTVLNNL
                     EWLITIVLAIMSVIQVEVGKIIKRKKLKK"
     regulatory      15087..15189
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            15299..16564
                     /locus_tag="KR294_002260"
     CDS             15299..16564
                     /locus_tag="KR294_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
                     /protein_id="HBH0240335.1"
                     /translation="MYNKETICVQGNYKPGNGEPRVLPLYQSTTFKYSSIDQLAELFD
                     LKVDGHIYSRISNPTIQAFEEKISLLEGGVSSVAVSSGQSANMLAVLNICKSGDSILC
                     SSKVYGGTFNLLGPSLKKFGIDLISFDLDSSEDEIVELAKENTKVVFAETLANPTLEV
                     IDFEKIANVAKRINVPFIVDNSLASPVLCNPLKYGANIVTHSTTKYLDGHASSVGGII
                     VDGGNFNWDNGKFPELVEPDPTYHGISYTQKFGNAAYATKARVQLLRDYGNCLSPFNA
                     YLTNLNVETLHLRMERHSENALKIARFLEKHENVDWINYPGLEDNKYYENAKKYLSRG
                     CSGVLSFGVRGGLENAKKFVEKLQIASLVTHVSDVRTCVIHPASTTHRQLTEEQLIAS
                     GVLPSLIRLSVGIENVEDLIADLNQALNF"
     gene            16594..17484
                     /gene="metA"
                     /locus_tag="KR294_002261"
     CDS             16594..17484
                     /gene="metA"
                     /locus_tag="KR294_002261"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HBH0240336.1"
                     /translation="MALILPKGLPVINKLLDEGIDVIYKEDFKKELKYEENIDTKIAI
                     LNLMPIKIDTELDLLRRIDKTGFNVSVEFIKISTRESKRSCNEYVKEFYKTFDEAKGE
                     YFDGFIITGAPVEQMEFEEVDYWNELEEIMDYSKRKTKSTLYICWAAQASLYKYYNVK
                     KLPLSQKCFGVFKHKVDKDSKIVDGFENEFFAPHSRHTTVNIEALKENKELSIVSHSK
                     EAGPYIITNSRDVFVMGHSEYDKYTLDKEYKRDINKGDKISIPQNYYINDDPSEEPTV
                     KWKKHSELLFRNWIKNYLIQ"
     gene            17972..18415
                     /locus_tag="KR294_002262"
     CDS             17972..18415
                     /locus_tag="KR294_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBH0240337.1"
                     /translation="MDEMSFKKELLELTRDINMKFTTLLSDFYQPLGITAVQALILSE
                     LCEHGEKKISDLGKNLNMTNSNVSVICQRLEKNGFLNRIRDIEDQRIVKVKVTNKSLD
                     IQEHISSSIFDSYFENMTSEKLQDMEDIIEGLEKLNKLLTYIDCK"
     gene            18446..20263
                     /gene="ftsH"
                     /locus_tag="KR294_002263"
     CDS             18446..20263
                     /gene="ftsH"
                     /locus_tag="KR294_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HBH0240338.1"
                     /translation="MDEHKPQKRSALYYYTVIIIVVMFLNALIFPSLMDKKMVEIDYG
                     KFLTMLDTGKVKSVEIENNRIAINPSSSKDKNIYITGRMDDPELVDRLKNAKVEFTKV
                     IPKENSPLLSILLTWIIPIGILMLFGNLMMKSMQKRMGGNAMQFGKSNAKMYVSAQSG
                     KRFNDVAGQDEAKEALTEIVDFLHNPEKYKKIGAQMPKGALLVGPPGTGKTLLAKAVA
                     GEANVPFFSISGSEFVEMFVGMGASRIRDLFKQAKEKAPCIVFIDEIDTIGKKRDNGS
                     GLGGNDEREQTLNQLLSEMDGFDGGIGVVILAATNRPDSLDKALLRPGRFDRRIPVEL
                     PDLGGREAILKVHAQNVNVSSDIDYNAIARSTSGASGAELANIVNEAALLAVKSGRDI
                     VEQQDFDESVETVIAGYQRKGAVISDKEKKIIAYHEIGHALVAAMQKHSAPVHKITII
                     PRTSGALGYTMQVAEDESVLMSKEEAIDKITTFTGGRAAEEVIFNTCTSGASNDIEQA
                     TKIARAMVTRLGMSEEFDMVALETVSNQYLGGDTSLACSSDTAAKIDEEVFKIVKACH
                     KNAIEILENNIDKLHELANYLLEKETITGDEFMEILNLN"
     gene            20441..23143
                     /locus_tag="KR294_002264"
     CDS             20441..23143
                     /locus_tag="KR294_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase KdpD"
                     /protein_id="HBH0240339.1"
                     /translation="MDRPNPDILLEKIKNEEEKLSRGQLKIFFGYAAGVGKTYSMLES
                     AQNLKKVGVDVVVGYIEPHTRPETLALLDGLEILPVKEIEYKSIKLKEFDLDAALARK
                     PEVILVDEFAHSNVAGLRHTKRWQDIEELLLAGINVYTTVNVQHLESLNDIVEIITNV
                     SVKETIPDKFLDTNTQLELIDVEPDVLLERFNEGKIYKKEQATRAKNNFFIKDNLVAL
                     REIALRKTAERVNKEVQMTRLSKGDVTVIPTSDTLLACISPSPSSAKVIRTASRISDS
                     TFAKWIALYVETPNTARLPFDEQKQLQNNLKLAKKLGGEIIVLHGENIIEQILRIAKL
                     RNVTKIVIGRNHSSNKRFSKRFKKDIVDKLIDEVDYIDIHIIPYKFASDVKYKPKKDK
                     SSIKSKFKISKVDFIKLIFITLMISILAYAVQSMGFIRENILLIYMLGVVLVSMWTKG
                     YSTGIISSVFNIVLLNYFFTAPLYTLSIADSNYIVTLVVFSIVGIITSTLTSKIQHEA
                     ETAAKREENTKMIYQIIKGFLRLSNKDDIVNKGIELLSLSLSRDVICYLNVDKHNKSK
                     LYKKNTNNKDKNDLDSEDEKAVASWVLSNSTVAGNDTDTLPGSKGYYIPIVGMNLTLG
                     VVGISCIDSKLDTEDISLIETIIAQMAIALDREILSEAKENTNLEIERERLRSNLLRA
                     VSHDLRTPLAGISGAVSTIIKNKGTIGQDIIDELLSGVYEDTQWLIRLVENLLSMTKI
                     DEGKLEVKKHSELVEEIISEALQKIKKRIENALIDINIPEQILFVPMDAKLIEQVLIN
                     LIDNSLKYSKEDCKIEINVYEKDDYVWFEVSDNGPGISKELKKHIFDRFFTGEEGAKD
                     SRKGVGLGLSICKSIIQAHKGEIMVENNKDKGSTFKFSLPKENE"
     gene            23177..23875
                     /locus_tag="KR294_002265"
     CDS             23177..23875
                     /locus_tag="KR294_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0240340.1"
                     /translation="MSKKLILLVEDDKTIRKFISTALLTQDYDVKEAITGKEGISIAV
                     SYSPDVVLLDLGLEDMDGIEVIKAIRQFSNIPIIVVSAREQDRDKVEVFDAGADDYLT
                     KPFSIVELLARVRVAFRHSQVEAQQKDDVKSTFEVDKLLIDFDKRKVIVDDVEVHLTP
                     IEYNILSLLAKYHGKVLTHNFIIKEIWGSVIGNETKSLRVFMATLRRKIEKQPANPRY
                     IITEVGVGYRLNDE"
     gene            24232..25188
                     /locus_tag="KR294_002266"
     CDS             24232..25188
                     /locus_tag="KR294_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CorA family divalent cation transporter"
                     /protein_id="HBH0240341.1"
                     /translation="MYILNLNTRETIEDFRDKFYVAENSYLILSAPKNLKLLKETLDI
                     DEITFNDCLKFDEITKLDLFDNYDFLSLNTFELRDGEAVIEEVNMYLSDNFILVVVNE
                     EHFLFEFVKNIILKNSQLEKNPVINLFKINYLILREVIKNGFESLEKVEELILQIEDE
                     MMDNINKNHVSRISDVRGLTRIIVKNTRPLLYIGDRIVKENIRYLKYSNVKKYNLENF
                     QGIDFGIDKLYNFALSTRELADKLLDIYSSRVGEKTNNLITKLTLLTAISAPLTIITG
                     IYGMNFRYMPELNWIYGYPATLFFMLCIIFVGIIIFKIKKLL"
BASE COUNT        10176 a         2693 c         4487 g         7943 t
ORIGIN      
        1 aaaaaaagtc tttttaactt taaaaattaa tgttaaaaaa taaacttata cattaatatt
       61 aataataatt atttaaatat cttaagtaaa tcagtcttac atatatttcc gatagattat
      121 attgataaaa aacactaaaa ttaaattaat aaaagtactt ggagggatgg aaatgaaaga
      181 ggaaaatttt attaatgttg aatacgagga taaacgtttt tcaattaata gtaaagaagt
      241 tttgtacata gaaaagcaag agtatgaagt aaagatttat actgaaagtg gtaattatga
      301 agttggagaa aatgctcctt gtataagaaa actattgaaa gaagaaaatt ttttcaaatg
      361 cagtaatagt tatattgtaa atctagacaa gtgtgaattt tatctcagca ataattgtat
      421 ttttgtgaat aataatttta taagaatttt aggttcagaa agaaaaaaga aattaaaaaa
      481 gaaattagaa aaattatatg attatgaaga ttaatattgg gaggctgtat tttatacagc
      541 ctctttattt attgattgta ttattaataa attttaaatt atgataaaat ataaaacaag
      601 taacttattt cagaataaaa tactttttaa aagaaaggga cgagatatgg gagattataa
      661 taaaatgctt gaattaaaga ataacttagg tatcagtgaa agaaagttaa aatatccttg
      721 tatctataaa catttcaaag ggaaatatta tgctacaatg ggtcttagca aggctattga
      781 tcatatagaa aacatatgtg aaatatatgg taaagaaaat ttaatccaaa acagaaataa
      841 atataaatta gttattagac atactgaaag agaagaagat atctatgttt atagggattt
      901 agatggaaac ttttatcata aaaaagaaga agatactaat gatttagttt tatacaagac
      961 cttatatgat gatacaggaa tatttgcaag acctttggat atgtttttag aaaaagtaga
     1021 tacagataag tatgtcaatt caattcaaga atacagattt gaagaagtat ataaataata
     1081 taagagaaat atgtttataa atttagaaaa attctttaac agtacaataa tttgcagaaa
     1141 tacaaatgag atttattgta aataatatgt tagattagat tataaaatag aaacaaagta
     1201 aagtattata tgatataatt aagttttgag aagtgataat ttatatttaa taaaaaatag
     1261 gcatatatta ggaggacata tgggaaatac tttttatata gtaagacatg gacaaacgga
     1321 ttggaatata ttgggaaaaa cacaaggtca tggtaattct gaccttacgc ctcaaggtat
     1381 agaacaggca aaagaacttt ctgaagatat tggcaagtat tcaattgatt atatttttag
     1441 tagcgacctt gggagagcaa tgcaaacagc tcaaatttta ggagataagc tcaatattga
     1501 agttcaaaaa actgaggcac ttagagaaat gggattcgga gtttgggaag gccttttaat
     1561 aaaagaaatt caaaaagatt attcagatat atatgcaaca tggagaaatg aaccacactt
     1621 agtaaatata ccagaaggcg aaactcttaa gattataaag gaaagagtag atgcttttat
     1681 aaaggaacta aatgaaaaat atgataataa aaatataatt cttgttacac attcaattac
     1741 attgagggtt atgttgttgt catttttaga atcaggtatg gaaaatatat atagaattaa
     1801 gcaagataat actgctttaa atatagtaga atttaaagat tatgggcctg ttatagtaaa
     1861 aatgaatgat acaagtcata taaaaaatca tgtaaagata aataattctg cactggagta
     1921 ggaatcaatt ataaggagaa atttatgagt aaagttatag tagttggtgg aggagcttct
     1981 ggaatgatgg cagctttgtc agcttcaaaa aacaataatg aagtaatatt agttgagaga
     2041 aatggagaat taggaagaaa acttagggca actggtggcg gtagatgcaa ttttaccaat
     2101 aatagagaga tagaagattt ttttgataaa gttgtcagta ataaaaaatt tctctatagt
     2161 agtttctata catttacaaa taaagacctt atttcgtatt ttgaaagtag aaatttggaa
     2221 tataagattg aagaagaaaa tgaccacaaa gtatacacta aaaatgataa atctatagaa
     2281 gtaatagaag tattaaataa agatttactc aatcacaatg taaagataat gtataataag
     2341 aaagttatag atattataac tgaagaaatt gctctaaaag atgattctaa taaggacaag
     2401 tcaaagtatc taataaaagg gattatttta gataatggag ataaaatact aggagacaag
     2461 gttattatat caactggagg agtgagttat tcaaagacgg gttcagatgg ttcaatgtat
     2521 aagattctta aaaagcatgg acatacatta aacaaactat atcctgcttt agttccactt
     2581 acaatagagg aaaaatggat taaagattta caaggaatat ccatgaagaa tgtggaaata
     2641 tcttgtaaga ttaagaaaag gaaaatatca aaatctggag acatgctatt tgcccatttt
     2701 gggataacag gaccttgtgt tcttataatg tcttcttata ttaacaagat tattgaaaag
     2761 gaaaaggtag aattaaatat agatttctta ccaaatttaa gtactgatga aatctctagt
     2821 ataatcagag catttccaaa taaaaatgtt ctaaataatc ttaagcaaat actacctcaa
     2881 aatttcttaa aagagatttt ttctctatta tctttagttg ataaaaaggc aagtgatttg
     2941 tctaaggcag atgaaattag aattattgag tatataaaaa atatgaagct aacttgtaat
     3001 gggactacag gtataaacac tggtatggtt acttctggtg gtatttcagt taaagaaatt
     3061 aattcttcta ctatggaatc taaattagtt aagaacttat tttttacagg tgaagtaatt
     3121 gatatagatg cagaaactgg tggatataat ttacaaatag cattttcaac tggatatctt
     3181 gcgggtataa gtgtataaat ataatttttt aataattaaa tatgaataaa tagaggtgta
     3241 tatatgggta atttagttat agctgtagat ggtccagcag gagctggaaa aagtacaata
     3301 gccaagatag tagcaaaaaa gctaaatata aattatatag atacaggtgc tatgtacaga
     3361 gcagttactt ataagtgttt aaaaagtggt attgatgtca ataatgaaaa agaagttatt
     3421 caaatagctg aaaattcgga tatagatttt aaagataaca atatatattt ggacaaagaa
     3481 gttataaatg aagaaataag aacaatagaa gtaagcaata atgtttctaa tgtagcaaaa
     3541 ataaaagaag taagacagtt gatggttgaa gttcaacgaa aaataggaat gaaaaattca
     3601 gtaatactag atggtagaga tataggttca tatgttttcc cagatgcaga ttacaaattc
     3661 tttttagtag ctactccaga agaaagagga aatagacgct ataaagaact ttgtaataaa
     3721 ggatataata ctactttaga agaagtaatt gaggatataa taagacgaga tgaaattgat
     3781 tcaaatagag aatttgcacc attggtaaaa gctaatgatg cactagaaat agatactaca
     3841 ggaaaaacta tagaagaagt tgtagaagaa gttgtatcta aaataaatct ttagtttttt
     3901 atgcatcata atgaaaataa atgtagtgtt gaagggagat aaacgtgaat ttttatagat
     3961 ttgtaataaa tatttttaag ggtttttcta aaatattttt taaatatgaa gttataggtg
     4021 cagagaatat tccagataga ggaaatatag taatagcatc aaatcataaa tcgaatcttg
     4081 accctatatt cttggctgct gccatagaaa atagagaaat agctgcaatt gcaaagaaag
     4141 aattgtttaa agtaaaacca ttgggattta tattaaaaaa attgcatgtt atgcctataa
     4201 atagagaaaa accagatgta tctacaataa aaactatttt aaggtcagtt agagacggtt
     4261 atgtattagg aatatttcca gagggtacta gaataaaagg agattctttt ggtaaggcta
     4321 aggcaggtct ttctgtattt acaataaaaa gtaaatctaa agttgttcca gtatcaataa
     4381 tatctaaata taaacttttt agtaaagtaa ttgtatatat tggagaacca atatcatttg
     4441 aagaacattt taaggaaaaa ttgagtaatg atgaccatga aaggatatca caagagattt
     4501 tagaagtgat aaaacaaaat tactttaaat attcaaaata agggggtaaa gttatgaaca
     4561 taaaaatagc aaaaaatgct ggcttttgtt ttggagtaaa aagagcaatg aaaatggcat
     4621 gggatgaagt tgaaaaaaat gattctggca tatatgcttt aggtcctctt attcataaca
     4681 agcaagcagt agcaaaatat gaagaaaaag gtcttaagac tgtgaatgaa attgatacaa
     4741 taccaaatca tgaaaatatg ataataaggt ctcatggagt tcctgaaaat atatataagg
     4801 aagccaaaga taaaaaatta aaaattgtgg atactacatg tccatttgta aagaaaatac
     4861 atacagtagt aagtgaatat cataataaag gctatgaaat aatagttatt ggagatatga
     4921 agcatccaga agttataggt ataaatggat ggtgtgaaaa ttcagctata ataataaaga
     4981 ccttagaaca aatggaaaat atggaatttg ataactccaa aagatattgt cttgttgcac
     5041 agactacaat aaatccagag ttgtatataa gtatagttaa taaactatca gataaattag
     5101 aagaaatagt atttaatgat acaatttgtt cagctacaaa aacaagacaa gaatcagcta
     5161 aagagttagc taaaaaagtt gattgtatga tagttatagg aggtaaacac agttcaaata
     5221 ctcaaaagtt agtaaaggtt tgtgaagact tagtaccaac ttttgcaata gagactaaag
     5281 atgaattgga tgtaaatacg cttaaaaaat ataaaaattt gggtattaca gcaggggcat
     5341 ctacacctaa ttggataata gaagaagttg taacattcct tgaaaattta taatttgata
     5401 ggtaataaaa ataggtggac attgttataa tttatcataa tatccacctt tgatttcata
     5461 ttacatgtgg taaatagata acctaatatc aaaaagtgtg tatcttaaga tgaaaaacta
     5521 agagtataag atgcgcactt tttaatatta gaaattcaaa agaaatattg atattgatta
     5581 tcaatagaaa atagaatata atataattgt tgcaaaatta gtctaggagg taaattaatg
     5641 gaaatgttga tatccgcttc tgaagaggcg tttttacatg taggttctat gattggattt
     5701 tttattttgt tatttggata tattaattat aaaactagtg gaaattttac taatatcata
     5761 tcaaaaaaca gaaaatttca acccttaata ggtgctttaa ttggagctat accaggttgt
     5821 ggcggaagtt tggcaataat gccattgtat ataaatggaa aattaagctt tggagcaata
     5881 attgcaagtt taatagctag tatgggagat gcagcatttg tacttatttc atcaaatatt
     5941 aaaatgtatt tttttgtcac tatagttagt acaattacag gaataataac tggacaatta
     6001 gtggattact ttaaactaga agaaaaatta gggttaaaaa accgtagaaa atcagataaa
     6061 tatgatataa gtaaaaataa ccctaaagaa aataaagaac aacataatca tgatgaaata
     6121 attttagaca ctctagctaa atctcatgga aatacaaata gacttgcatt tataataaca
     6181 catggaaagg gatataaaat ttatatagga attatagtaa tcggttttat atttatgtca
     6241 cttgctcact ctggacttaa tcttcctata attgagaagt tacattcatt ggaagaagta
     6301 atagcagtga ttggaatatt attttcaata atttatatgt ggtgttttaa aaaggtattt
     6361 aaaaattcta atcaaaaaga ggaagaaaat aaaaagattt ctttgcgaga aatgcttatc
     6421 cattctgttg gagaaatatc atttgtaatt acatggattt ttattgcata tcttatttac
     6481 gatttgataa tattaatttt aggtggagat gaatacttag ttaaattagt attatcaaca
     6541 ggtgtaataa gtgtatttat aggtgcaggt cttggactta ttccaggttg tgggatacaa
     6601 attgtgctta tgtcatttta tttgaaggga actataccac ttggtgcagt gatagccaac
     6661 tctatttctc aagatggaga tgcacttttc ccacttttag caatggataa aaaatcttct
     6721 ttatgggcta tgattattac tactatacca gcaatacttg taggtatgat agtttatgca
     6781 tttttaggtt aaatataatt atgaataaag aagtattaaa aaaataataa agcacataaa
     6841 tttatttata agaatagtga agattaaata taaaaataaa aaattcaata tgaattaaat
     6901 tattgcttaa atattaatga gaacatggga gataatatta ttcctcatgt tctctctatt
     6961 taattaaagg aattatggaa caaatttcaa gtgatacttt ctatcaaaac tcatatataa
     7021 tatatattaa taaattaaac tataatacgt aatacagtca gtatattgat ataaaaaact
     7081 taggaggagt tgtaaaaatg ggtaatttaa aaagacagtg tgatgtttca agtggaagag
     7141 aaaaagctga cattgtacta aaaaatggga caatcataaa tgtatttaca gaagagttaa
     7201 taacaggaga tgtagcaata gtaggagaca ctatcgttgg aattggcgat tacaagggca
     7261 atgtagaaat tgattaaaaa atagctacgc acactcgtga ctttagtcat gagttagtag
     7321 ctaaaatagt cagcatatag ggaaacctat atgtagagat aggatagaac ctatccaata
     7381 ctacttgaat tgctggaaac ccctaaagct aatcaaacta aaacataagg atgaaataaa
     7441 cctaagtgtg aaagttacga aagtagaaaa aattggttag atggtataag gttaaaccct
     7501 aagtacttta aaatgggcaa tcagcaggta aactccgaat aggagaaact tcaacgacta
     7561 ttcctcttga gggaagtaca ctacaagcta ttggtagtgg aagtgggtag accttaacgg
     7621 ataatgctga aggataagat atagtctgtg cttgcatgaa agtgtaagaa gttcataaga
     7681 gaactgcata ggtagtagcg aacttatgtg aacgacaacc tcaaaaatga taaaagttaa
     7741 gacttacggt tcttaaatat gttatttaaa attaaatata aaaccttcta aataattgtt
     7801 ttaaataatt acatttgtta acattattat aggtgattaa taaattgttc accacagcat
     7861 tatataatat attaaatatg ataaaatcat taaaaagtgt atcaaaaaac aattaaagtg
     7921 aggtgatagt agtggaaaaa gcttataagt ttagaatgta tccaaataaa aaacagcaag
     7981 agttaattaa caaaactttt ggatgttgta gatttgtgta taataagtat cttgctaaaa
     8041 gaatagatgt ttataaaaaa cataaagaaa cttttactta taaacagtgt agttctgatt
     8101 tgaccaattt aaaaaaagaa ttaaagtggc ttaaagaacc tgacaaattt tcactacaaa
     8161 acgccttaag agatttagat aatgcatata aaaaattctt taaagaaaaa gcaggatttc
     8221 ctaaatttaa atcaaagaaa attaatagat tttcatataa aactaacttt acaaatggaa
     8281 acattatgta ttgtggtcaa catataaaac tacctaaact tggtatggtt aaggtaaggg
     8341 ataaacaagt acctcaaggt agaatactta atgctactat atctaaagaa ccaagtggta
     8401 gatattatgt atcattatgc tgtactgatg tagatattgg agcatttgaa aatactaata
     8461 atcatatagg tttagattta ggaattaaag aattttgtat ctcaagttgt ggagacttta
     8521 tagaaaatcc taagtatctt aagaagtcat taaacaaact tgctaaatta caaagagaat
     8581 tatcgagaaa aacaatcggt agtttaaata gaaataaagc aagattaaaa gttgcaagat
     8641 ttcaagaaca tatagctaat caaagaaagg attttctaca aaaattatct actaaattaa
     8701 taaaagagaa tgatattatt tgcatagaag atttacaagt aaagaatatg attagaaatc
     8761 gtaaactatc tcgcttaatt tctgatgtgt catggtcaga gtttattcgt caattagaat
     8821 acaaggctaa ttggcatggt agacaaattg taaaggtagg taaattcttt gcaagttcac
     8881 aaatatgcaa taaatgtggg tataaaaacg aggaagtgaa ggacttaaat ataagagaat
     8941 ggatttgtcc tagttgtaat gaaactcacg atagagatat aaatgcaagt ataaatatat
     9001 taaaagaagg attaagacta ataacaattc aaaataaata acgtatgtaa gaaccgtagg
     9061 aactacgggg atagcctgtg gagaattagt aagacatatt ttagtatgca aaattctgtg
     9121 aagcaggaac cctgtgactt tagtcatggg aggttcagtg tagcaataaa tatatatcac
     9181 ctggctttat tgatgcacat atgcatattg aatctacaat ggtaatgcca attgaattat
     9241 cgaaaaaatt attaaaatca ggtacgacaa ctatcatagc cgacccacat gagttggtca
     9301 atgtaaaagg agttagtgca atagattttt tattagaatc gacaaaagat ataccactta
     9361 atgtatatat tatggtgcct tcatccgtac ctgcaacaag ttttgaaact aatggagttg
     9421 gtaaatttag tgcaaaagac atggagagtt atgtaaataa tcctagaatt ttaggtttag
     9481 gagaggtaat gtgttttaat gatgttataa attctgaaaa tgaaatcttg gataaactag
     9541 agctttttaa aaataaagtt gtagatggac atgcacctaa tataaatggt aaatcacttc
     9601 agacatatgt atgtgcagga atagaaaatg accatgaatg tataactttt gatgaagtat
     9661 atgaaaaatt gagagcagga ttaaaaattt taataagaga aggaagcgca gcaaaaaatt
     9721 taaagtctat agtaagtggt atgctaaagc ataacttgcc aattgaagaa tttatgtttt
     9781 gcacagatga taagcactta gatgatatag aaaaacaagg tcacataaga tggaatataa
     9841 aatgtgcgat tgatttaggt atggaacctg ttagggctat aaaagttgca acttataatt
     9901 ctgcaaaagc atatgggtta aggaaaattg gagcaatagg tgcgggttat aaggcagata
     9961 ttgttgtatt gaatgattta gacaaaatgg aagtggatag tgtatataaa gatggtaatt
    10021 tggtaaacga agagatgttt tctaattaca attatgagat taaagataaa gaattgctta
    10081 atacagtcaa gtttaaatat attaataaag aaaaaataca gttaaaagta agtgaaaaaa
    10141 attatgtaat ggagattgta ccttatcaaa ttttgacaaa taaggtatat gaatctttac
    10201 catgtgcaga tggatatttt gttccaaata aagagtattc aaaactttgt gttgttgaga
    10261 gacatagaat gactggaaat gtagcagttg ctccactaaa aggatttggc ataaaaaatg
    10321 gagcaattgc tactactgtg gcccatgatt ctcataatat tatagttgca ggggataatg
    10381 atgatgatat tctagtagct ataaattact taaaggaaat acaaggtggt tatgtaattg
    10441 tatcaaatgg aaaagttctt gcacacctaa gtcttcaagt agctggatta attagtactt
    10501 ttacagctga agaagtacaa gaaattactg ataatatgtt ggagatagca agaaaaatgg
    10561 gagttccaga gtatgtagac ccttttatta cactttcttt tatggcactt ccagttgttc
    10621 cacaaataag acttacagat ttaggtctat ttgatgttga ggaatttaaa tttatataga
    10681 taatataaaa gtaataataa atgaggcttt ctcaaaatag ggataagtct ctttttattg
    10741 ttgaaatgat aaaaatatat ttgatttcat acaaaaaaga gcatctcatg aactaaaaat
    10801 tttattttta gatatcctta ttttaattaa tctatcattt aaccttgttt taagcataga
    10861 tatcttaata aaactatttt cagtctattt taacatataa atacatgaaa attatatatt
    10921 tatgaaactt tatacataaa aaataaaata ttttatttat atatagattt atagggtaat
    10981 aatataagca tagtataaaa ttattaataa aaacaaaagg agagatattt atgttgagta
    11041 taggaacaaa agcaccagaa tttacactag aagataaaga tggaaataag gtaagtatgt
    11101 cagattttaa aggcaaaaaa gtagtagtat atttttatcc taaagataat acaccaggat
    11161 gtacacgtca agcttgtgct tttagaaatg catatgatgg atttaaaaag gaagatatac
    11221 aagttattgg gataagtaaa gatagtataa aatcacatca aaaatttgca gaaaagcatg
    11281 aacttccttt tattttactt tctgaccctg acttagttgc tataaaagct tttgatgtat
    11341 ggaaagagaa aaaaatgtat ggaaaaactg cattgggagt tgtacgtgcg acatatatta
    11401 tagatgaaaa tggaattatt gaaaaagtct ttgaaaaagc aaaaccagac acaaatgcac
    11461 aagagattct tgaatatttg gaaaaacagg agtaataaga atttatgatt ataatgttat
    11521 caccagctaa aaatatgaag aatatagaag tatttgatag agatttgagt ttgccttgct
    11581 ttatagataa cacaaaagaa atagtggaaa atataaagac atttggtata gaagatttta
    11641 aaaataaaat gaaaattaat gaaaaattag ctgtattaaa taaaaataga tttgaaagca
    11701 ttaaatttga tagattagga aaccctgcaa tcttaactta tgatggaata caatataaaa
    11761 atatagaagc agaaaatttt acaaggaaag atgaagagtt tgcaaatagc tgtattcgaa
    11821 tcataagtgg attgtatggt gttgtaaaac catatgatag tatatatgaa tatagattag
    11881 aaatgcagac aaaattacga gtaggtgagt ttaagaattt atacgaatat tggggaaatc
    11941 gtatatataa agaactaatc aaagaaaaaa cagctatcgt taatctttca tcaaatgaat
    12001 acagcaaatc catagaaaaa tttattaaag atagtgatac atatattaca tgtactttta
    12061 aagtaaataa aaatggcata ttaaaagtgg aatctacaca agcaaagaaa gctagaggta
    12121 tgatgacaaa atacattgta aaaaatagga taagagatat tgaagaactg aaaaagttta
    12181 atttagaagg ttataagtat aaagaaaact tatctaacaa tagtgaatac atatttgtaa
    12241 aagagtagaa gttttgttaa atattaaatg gcattgttaa atttaggtaa aatatactta
    12301 gtgtgtattg aattgaactt gattttaaaa tataattatt cttaaattaa aaaaagaaag
    12361 gagtggtctt ccaaaatgga aaatcacaaa cagatgcctt ggcattcaag agcaacgcat
    12421 gaaattttag aaagtctaga ttcatcagag gaggggctca ccgataccga ggcggaaaaa
    12481 cggcttaaag agaatggctt aaatgaactt agaaaaaaac cacctagaac aactttacaa
    12541 atgctttgga gtcaaattac agatgctatg gttatgatac taataggagc agcaatatta
    12601 tctttgatat ttggcgaatt tacagaagct tttgtaatac taataattgt aacagtaaat
    12661 gcagttattg gaattgttca agagaaaaaa gcagaatcat cattagaagc attaaaaaat
    12721 atgaactcac ctacagctcg tgttatgcgt gatggtgaag aaaatgttat tccagcaagt
    12781 aatcttgtag taggagatat tgttttttta gaagatggag ctatggttcc agcagacctt
    12841 cgtttaatag aaacatcaag tttaaaaatt caagaggctt ctttaacagg agaatctgtt
    12901 ccatcagaaa aagatgcaga tacaatctta cctaaagaat gtgtattagg agaccgtagc
    12961 aatatggcgt atacatcttc aatagtcaca tatggtagag gtgtaggtgt tgtagtagca
    13021 actggtatgg atacagaagt gggtaacata gcacatcttt tagattcaca agatgatttt
    13081 gatactccta taaaacgtaa acttaatact gttggaaaga cattaagtgt cataggtatt
    13141 attgtatgcg ttgttatatt tgcaataggt gcattttatc agagacctct cttgccaatg
    13201 tttatgattg caatttccct tgccatatca attattccag agggattacc tgcaacagct
    13261 actattgtaa tggctttagg cgtacagcgt atggctaaaa gaaatgcttt aattagaaaa
    13321 ttacctgctg ttgaaacatt aggaggagct acagtaatat gttgtgataa aactggtacg
    13381 ttaaccttaa ataaaatgac tgttacacat attgctgtca atggagattt tgaatctgga
    13441 aaagtgacat caatagatac tgcatctgaa aaacatccat tagtgtataa agagattgtt
    13501 tatgctggtg cactttgtaa tgatgcatgt attaatccag ataaaacaga tgaaatatta
    13561 ggtgacccaa cagagggcgc attaattttt atggccaaaa aatttggaat agatcaagaa
    13621 gctcttgaag aagaatatcc acgtgtattt gaacagcctt ttgattcaga tagaaaatgt
    13681 atgacaactg ttcataatat agatgaaaag attattgctt atactaaagg agcagtagac
    13741 gaaattcttg acctatgtac taaaatatta acttcaaaag gtgaaagaaa cattaccgaa
    13801 gtggataaaa agaatataca cgaattatgt cttaacatgt ctaaagatgc attgcgtgta
    13861 cttggttttg ctaagcgtga gatttcatct ataccaaaag aagatagtga aaatatagaa
    13921 tatgatttaa catttatagg tatggttggt atgattgacc caccaagaac tgaggtaatt
    13981 gatgcagtaa gtacttgtaa agaagcaggt ataagaacca taatgataac aggtgaccat
    14041 aaagttactg ccacaacaat cgctcatgag ttaggaatat ggagtgaaga aaatactgtg
    14101 atatctggtg atgaacttga taatttgagt gatgatgaac tagatgaagc tgttaaaaat
    14161 actacagtat ttgctcgtgt atccccattt gataaactta gaattataca atctctaaaa
    14221 agaattggag aagtaccagc aatgactggg gatggtgtaa atgactctcc tgccttaaag
    14281 tctgctgata ttggtatagc catgggtata agtggtacag atgttgcaaa agattcttct
    14341 gacatgattt taatggacga tagttttaca acaattgctt atgcaataaa agaaggtaga
    14401 cgtgtatata gaaacataca aaaagttata caatttttgc ttgttggtaa tatagcagag
    14461 atacttacgt tgtttgtagc aatattatta aattgggata ctccgcttct tgctgttcat
    14521 attctatggg taaaccttgc aactgctacg cttccagccc ttgctcttgg agttgaccca
    14581 ccaagcagaa atataatgaa gcaccagcca gtgaaatcaa ccactttgtt tgaaaaaaat
    14641 cttatacaaa gagttgttac ccaaggtata tttgtggcaa taatgactat tttagcatat
    14701 aaaattggtc ttaatataga aaatcattct gtaggtcaaa caatggcatt ttgtgtatta
    14761 gcattttcac agatgttacg agcatttagt cagcgttcaa atacagattc aatgtttaat
    14821 agaaataatg gtaaaaatcc atttctttta atctcatttt taacttctgc atttttaata
    14881 gcagtaatac tatttgcacc tgtttttaga aatgctttta acttaacagt tttaaataac
    14941 ttagagtggc ttataacgat tgttttagcc ataatgtctg taattcaagt agaggttggg
    15001 aaaattatta aaagaaaaaa attaaaaaaa tagttgacaa aattaggaaa aatatataag
    15061 atataaaaca tagaaaaatt aaataaatct tatccagaga ggtggaggga ctggccctat
    15121 gaaacccggc aaccagtata tttatataca gtggtgctaa atcctgcggc gaaagctgag
    15181 agatgagtat aattaagctt atacagagcc tgagttatat actcaggctt tatttatttt
    15241 aactctcatc tggtaaatag tttaattttt tttactaaaa tctaaggggg atacaagaat
    15301 gtataataaa gaaacaatat gtgtgcaagg aaattataaa ccaggtaatg gagaaccaag
    15361 agtactacct ttatatcaaa gtacaacttt taaatatagc agtatagacc aacttgctga
    15421 attatttgat ttaaaagttg atggacatat atattcaaga ataagcaatc ctactattca
    15481 agcttttgaa gaaaaaataa gtttactaga gggtggagta tcttctgtag ctgtatcatc
    15541 agggcaatct gcaaatatgt tggcagtttt aaatatatgt aaatcaggag atagtatact
    15601 ttgttcttca aaagtatatg gaggaacatt caatttacta ggacctagtc ttaaaaaatt
    15661 tggtatagat ttaatatcgt ttgacttaga ttcaagtgaa gatgagatag tagaacttgc
    15721 aaaggaaaat actaaggttg tgtttgcaga aacacttgca aatccaactc ttgaagtcat
    15781 agattttgaa aaaatagcaa atgtagctaa gagaattaat gttccattta ttgttgataa
    15841 ttcattagca tctccagtgc tttgtaaccc tttaaagtat ggagcaaata tagttactca
    15901 ttctaccaca aaatatttag atgggcatgc ttcaagtgtt ggaggaatta tagtggatgg
    15961 tggaaacttt aactgggata atggaaaatt tccagaatta gttgagccag acccaacata
    16021 tcatggtata agctatactc aaaaatttgg aaatgccgca tatgcaacta aagcaagagt
    16081 tcagttgctt agagactatg gaaattgttt aagcccattc aatgcgtatc ttactaattt
    16141 aaatgttgaa acactacatc ttagaatgga gagacatagt gaaaatgcac ttaaaatagc
    16201 tagattttta gaaaaacatg aaaatgtaga ttggattaat tacccaggac ttgaagataa
    16261 caagtattat gagaatgcca aaaagtattt atcaagagga tgtagtggtg ttttatcatt
    16321 tggagtaaga ggtgggttag aaaatgccaa aaaatttgtg gaaaaattac agatagcatc
    16381 tttggttaca catgtttcag atgtaagaac ttgtgttata catccagctt caactactca
    16441 tagacaatta acagaggaac aattaattgc atctggagta ttgccttcac taataagatt
    16501 atctgttgga atagaaaatg tagaggattt aatagctgat ttaaatcaag ctttaaattt
    16561 ctaatattct aagagaaaga gaagtgaaaa gatatggctt taatactacc aaagggatta
    16621 cctgttatta ataaattatt agatgaagga atagatgtaa tttataaaga agattttaaa
    16681 aaggaattaa agtatgaaga aaacatagac actaagatag ctatactaaa tctaatgcct
    16741 ataaagatag atacagaatt agatttacta agaaggatag ataaaacagg attcaacgtg
    16801 tctgtggaat ttattaaaat ttcaacaaga gaaagtaaaa gaagttgtaa tgaatatgtt
    16861 aaagaatttt ataaaacatt tgatgaagcc aaaggagagt attttgatgg ctttataata
    16921 acaggagctc cagttgaaca aatggagttt gaagaagttg attattggaa tgaactagaa
    16981 gaaattatgg attattctaa gagaaaaact aaatctacat tatatatatg ttgggcagct
    17041 caagcaagtc tttacaaata ctacaatgta aaaaaacttc cactaagtca aaaatgtttt
    17101 ggagtattta agcataaggt agataaagat agtaaaatag tagatggatt tgaaaatgaa
    17161 ttttttgctc cacattcaag acatactact gtaaatattg aagctttgaa agagaataaa
    17221 gagttgagca ttgtgagtca ttctaaagaa gctggtccct atataattac aaattcaaga
    17281 gatgtgttcg taatgggtca tagcgagtat gacaaataca ctcttgataa agaatataag
    17341 agggatataa ataaaggaga taaaatatct atacctcaaa attactatat taatgatgac
    17401 ccttcagaag agccaactgt aaaatggaaa aaacattcag aattgttgtt tagaaattgg
    17461 ataaaaaact atttgataca ataaatttta agagtatata aatgttaact aaaaaaatat
    17521 agaaatttat aggtataaag ttaatcttaa tgatacttta taccttattt ttttaaaatt
    17581 tgaccttata atagtagttt tatattttaa gaaaatcact ttaggtgtat gtagatagag
    17641 gtggctttaa ttttatatat ggtgcgataa tgggagacta aacctttata gtatcaataa
    17701 atttgtattt taacttttaa aagagattaa aaagggagaa atcagtgtaa aatatatata
    17761 gattttttat taaattttat taaaaatatc ctgtataaaa ttaaatatca ataagataac
    17821 aaaatttcaa ttgaagttac aatattgtaa ttgacaataa atacttaata ctataatatt
    17881 taatacatta aacattatag tgttaagtat ttattacagt atgcacttca gcctaaattt
    17941 gaaataaagt attttcgtag ggagcgtttg tatggatgag atgagtttta agaaagagct
    18001 actagagttg actagagata taaatatgaa atttacaact ttattaagtg atttttatca
    18061 gccacttggt attacagcag tgcaagcttt gattttatct gagttatgtg aacatggaga
    18121 gaaaaaaata agcgatttag ggaagaactt aaacatgaca aatagtaatg tatcagtaat
    18181 ctgtcaaagg cttgaaaaaa atggcttttt aaatcgcata agagatatag aagaccaacg
    18241 aattgtaaaa gtaaaagtta caaataaatc attggatata caagaacata tttcaagtag
    18301 tatttttgat agttattttg aaaatatgac cagtgaaaaa ttgcaagata tggaagatat
    18361 aatagaaggt ttagagaaat taaataaact tttaacttac attgattgca aataacataa
    18421 aaataattta aaggagaata aaattatgga tgaacataaa ccccaaaaaa ggtcagcact
    18481 ctattattat acagttataa taatagtagt aatgttttta aatgctttaa tatttccaag
    18541 tttaatggat aaaaaaatgg ttgagattga ctatggaaag tttctcacaa tgttggatac
    18601 aggaaaggtt aaatctgttg agatagaaaa taatagaata gcaataaatc catctagtag
    18661 caaggataag aatatataca taactggtag aatggatgac ccagaattgg tagatagact
    18721 aaaaaatgca aaagtagaat ttactaaggt tattcctaag gaaaattcac ctcttttaag
    18781 tattttactt acatggataa tacctatagg tattcttatg ctatttggta acttaatgat
    18841 gaagtctatg caaaagcgaa tgggtggtaa tgctatgcaa tttggaaaaa gcaacgccaa
    18901 aatgtatgta tctgctcaaa gtggaaaaag atttaatgat gtagctggtc aagatgaggc
    18961 aaaagaagct ttaactgaaa tagtagattt cttacacaat ccagaaaagt ataaaaagat
    19021 aggagcacaa atgcctaaag gagcactttt agtaggacct ccaggtacag gaaaaacact
    19081 ccttgcaaaa gctgtagcag gtgaagcaaa tgtaccattt ttctcaatat ctggttctga
    19141 gtttgttgag atgtttgtag gaatgggagc ttctaggatt cgtgatttat ttaaacaagc
    19201 aaaagaaaaa gctccatgta tagtgtttat agatgagatt gatactattg gtaaaaagcg
    19261 tgataatgga agtggattag gtggaaatga tgaacgtgaa caaactttaa atcagttgtt
    19321 aagtgagatg gatggttttg atggtggaat tggagtagta atacttgctg ctacaaatag
    19381 acctgacagt cttgacaaag cattacttcg tccaggaaga tttgatagac gtataccagt
    19441 tgaacttcca gaccttggag gacgtgaagc tatattaaag gtacatgctc aaaatgtaaa
    19501 tgtaagctca gatatagatt ataatgcaat tgcaaggtct acatcaggag catcaggtgc
    19561 agaacttgca aatattgtaa acgaagcagc acttttagca gttaagtctg gcagagatat
    19621 agtagaacaa caggattttg atgaatctgt tgaaactgta attgctgggt atcaacgtaa
    19681 aggagctgta atttcagata aggaaaagaa aattatagca tatcatgaaa taggtcatgc
    19741 acttgttgct gctatgcaaa aacattctgc acctgtccat aagattacta taatacctag
    19801 aacttcagga gcattgggat atactatgca agttgctgaa gatgagagtg tacttatgtc
    19861 taaagaagaa gcaattgata aaataactac ttttacaggt ggtcgtgctg ctgaagaggt
    19921 tatctttaac acttgtacat caggagcatc aaatgatata gaacaagcta ctaaaattgc
    19981 aagagctatg gttactcgcc ttggtatgag tgaagagttt gatatggtcg ctcttgaaac
    20041 tgtaagcaat caatatttag gaggagatac ttctcttgct tgttcttccg acactgctgc
    20101 taaaatagat gaagaggtat ttaaaatagt aaaggcttgt cacaaaaatg caattgaaat
    20161 cttagaaaat aatattgata aattgcatga acttgctaat tatttattag aaaaagaaac
    20221 tattacaggt gatgagttta tggaaatact taacttaaac taaaatgatt atacacaaga
    20281 taaaaatgcc tattgttagg catttttatt ttacaactaa attttttaaa ttcatattta
    20341 aatctttaca taatcttaat cattaaaaat acatcttaac tacaatttta tatcggaatt
    20401 gatattataa tagtaatgaa tggtgtaagg aggtttttta atggatagac ctaatcctga
    20461 tattctatta gaaaaaatta aaaatgaaga agaaaaacta agtagaggtc aattaaaaat
    20521 attctttggt tatgcagctg gagtaggaaa aacctactct atgttggaat ctgcacaaaa
    20581 tttaaaaaaa gtgggtgtag atgtagtagt tggatatatt gaaccacaca ctagaccaga
    20641 aacattggct ttacttgatg gcttggaaat tcttcctgta aaggagatag aatataaatc
    20701 tataaaacta aaagaatttg atttagatgc tgctttagca agaaaaccag aagttatatt
    20761 agtagatgaa tttgcccatt ctaatgttgc tgggttaagg catacaaaaa gatggcaaga
    20821 tatagaagaa ttgctgttag caggcataaa tgtctacact actgtaaatg tacaacattt
    20881 agaaagtcta aatgacattg ttgagataat tacaaacgta tcagttaaag agactatacc
    20941 agataagttt ttggatacaa atacacagtt agaacttata gatgttgaac ctgatgtact
    21001 tcttgaaagg ttcaatgaag gtaagatata taagaaagaa caagctacta gagcaaaaaa
    21061 taattttttt ataaaagata acctggttgc acttagagaa atcgcactta gaaaaactgc
    21121 agagagagtt aataaagaag ttcaaatgac cagactatca aagggtgatg taactgtaat
    21181 acctacatca gatacacttc ttgcatgtat aagtccatct ccatcttcag caaaagttat
    21241 tagaactgca tccagaatat cagacagtac atttgcaaaa tggatagctt tatatgttga
    21301 aactccaaac acagcaagac ttccatttga tgaacaaaaa caactacaaa ataacctaaa
    21361 attagctaag aaattaggtg gagaaataat tgttttacat ggtgaaaata taatagagca
    21421 aatacttaga attgcaaagc tgagaaatgt aacaaaaatt gtaataggta gaaatcattc
    21481 aagtaataaa agatttagta aaagatttaa aaaagatata gttgacaaat taattgatga
    21541 agttgattat atagatatac atataattcc atataaattt gcctcagatg ttaaatacaa
    21601 acctaaaaag gataaatcat caataaaatc taaatttaaa attagcaaag ttgattttat
    21661 aaaacttata tttattactt tgatgataag tattttagca tatgcagtac aaagcatggg
    21721 atttataaga gaaaatatat tgttaatata tatgttgggt gtagttttag tttctatgtg
    21781 gactaaaggg tatagtacag gtataataag ttctgtattt aatatagttc ttttaaatta
    21841 ttttttcaca gcaccattat atacattatc tatagcagat tcaaactata tagtaacact
    21901 ggttgtattc tcaatagtag gtataataac tagcactctt acgtctaaga tacagcatga
    21961 agcagaaact gctgctaaaa gagaagaaaa tacaaaaatg atatatcaaa taattaaggg
    22021 atttttaaga ttatcaaata aagatgatat agtaaacaaa ggtatagaac ttttgtctct
    22081 tagcttaagt agagatgtaa tttgttattt aaatgtagat aagcataata aatcaaagct
    22141 ttacaaaaaa aatactaata ataaggataa aaatgatttg gatagtgaag atgaaaaagc
    22201 tgttgcaagt tgggttttat ccaattcaac agtagcagga aatgacacgg atacacttcc
    22261 tggttcaaag ggatactata taccaattgt aggaatgaat ttaactttag gagtagtggg
    22321 aatatcatgt attgattcaa aattggatac agaagatata agcttaattg aaacaataat
    22381 tgctcaaatg gcaatagcgc ttgatagaga aatcttgtca gaagctaaag aaaataccaa
    22441 tcttgagatt gaaagggaaa gattaagaag taatctttta agagcagttt cgcatgacct
    22501 tagaactcca ctagcaggaa tatctggtgc agtaagtaca attataaaaa acaagggtac
    22561 tataggtcaa gatataatag atgaattact tagtggtgta tatgaagata ctcagtggtt
    22621 aataagactt gttgaaaatt tacttagtat gaccaagata gatgaaggga aattggaagt
    22681 taaaaaacat tctgaactgg ttgaggaaat tatatcagaa gcgttacaaa aaataaaaaa
    22741 aagaattgaa aatgcactta tagatattaa tataccagaa cagatattat ttgttcctat
    22801 ggatgcaaaa ttaatagaac aagttttaat taatttaata gataattctt tgaaatattc
    22861 aaaggaagat tgtaagatag agataaatgt atatgagaaa gatgattatg tttggtttga
    22921 agtatctgat aatggtcctg gtatatcaaa ggaacttaaa aagcatatct ttgacagatt
    22981 ttttactgga gaagaaggag ctaaagattc cagaaagggt gttggacttg gattatcaat
    23041 ttgtaaatct ataattcaag ctcataaagg tgaaattatg gtagaaaaca ataaagataa
    23101 gggttcaact tttaagttta gtttgcctaa ggaaaatgaa tagttttaaa ttttaaaatt
    23161 agttttggag gaagaaatga gtaaaaaact tatattgtta gtagaggatg ataagacaat
    23221 aagaaaattt atatctactg cacttttaac acaggattat gatgtcaagg aggctataac
    23281 tggaaaagaa ggtatatcta tagctgtctc atattctcca gatgttgttc ttttagattt
    23341 aggcttagaa gatatggatg gaatagaggt aataaaagct atcagacaat tttcaaatat
    23401 accaataatt gtagtttcag ctagagagca agatagagac aaggtagaag tatttgatgc
    23461 aggggcagat gattacttaa caaaaccatt ctccatagta gagttattag caagagtaag
    23521 agtagcattt agacattcac aagtagaagc tcaacaaaaa gatgatgtta aatctacgtt
    23581 tgaagtagat aaattattga ttgattttga taaaagaaaa gttattgttg atgatgttga
    23641 agtccatttg acacctattg aatataatat tctttcatta cttgcaaagt atcatggaaa
    23701 agtgcttact cataatttta taataaaaga aatatggggt agtgttatag ggaatgagac
    23761 taagtcttta agggtcttta tggcaacgtt aagacgaaaa atagaaaaac aacctgcaaa
    23821 cccaagatat ataattacag aagttggtgt aggatacaga ttaaatgatg aatagttgta
    23881 atatattaat tattagatta tgtgcttatt aatatatatt aaaattatat agtttagtta
    23941 aaataagaat gaagtgtatg tgcttgttgt cagtttagca catgcatttt attttttagc
    24001 ttttttagta tcaataattt tttagtatca ataatatgaa atatgtttta aaataagtat
    24061 atagtgtaat ctgtaataaa aactttggtt aaataataaa tgtatttaac acttacctta
    24121 taataaattt aatataaata ttaaataata attattaaaa tagtgtaaaa taattacagt
    24181 aaggattata aaaaattttt agaatgtaaa ttgaaattta ggagtagatg tatgtatata
    24241 ctgaatttaa atacaagaga gactattgaa gattttagag ataaatttta tgtagcagaa
    24301 aattcttatc ttatattaag tgctccaaaa aatttaaaat tgcttaagga aactttggat
    24361 atagatgaaa taacttttaa tgattgtctt aaatttgatg aaataaccaa acttgattta
    24421 tttgataatt acgatttttt aagcctaaat acatttgaac taagagatgg agaagctgtt
    24481 atagaagagg taaatatgta tttatcagat aattttatat tggttgtagt gaatgaagaa
    24541 cactttttat ttgaatttgt aaaaaatatt attttgaaga actctcaact tgaaaaaaat
    24601 ccagttatta atctatttaa gataaactac ttgattctta gagaagttat aaaaaatggt
    24661 tttgagtctt tggaaaaagt tgaagagtta attcttcaaa tagaagatga aatgatggac
    24721 aacattaata agaatcatgt atctagaata agtgatgtaa gaggattaac aagaattata
    24781 gttaagaata ctagacctct tttgtatatt ggggatagaa tagttaagga aaatataaga
    24841 tatttaaaat attcaaatgt aaaaaaatat aatttagaaa attttcaagg tatagatttt
    24901 ggaattgaca aattatacaa tttcgcattg tcaacacgag agttagcaga taaattatta
    24961 gatatttatt cttccagagt aggtgagaaa acaaataact taattacaaa attaaccttg
    25021 ttaacagcca tatcagcacc acttacaatt ataactggta tatatggaat gaactttaga
    25081 tatatgccag aattaaactg gatttatgga tatccagcaa ctttattttt tatgctatgt
    25141 ataatttttg ttggaattat aatatttaaa ataaaaaaat tattgtaaat tacagatgat
    25201 gtttaattga ttttataaaa atacatcaat tgagaagctg atttaagtaa ataaaaaaat
    25261 attttaaatt gaaaatattt atagaaaata ttgacaatt
//
LOCUS       DAEPKC010000055        24526 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.055, whole genome shotgun sequence.
ACCESSION   DAEPKC010000055 DAEPKC010000000
VERSION     DAEPKC010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 24526)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24526)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24526
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.055"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(483..659)
                     /locus_tag="KR294_002267"
     CDS             complement(483..659)
                     /locus_tag="KR294_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240342.1"
                     /translation="MFIGEIDKCTHILTAYISSSYDYCNFLDTQLDDFISEYGETVVE
                     TCLHQVLLLVSRYN"
     gene            1234..2256
                     /locus_tag="KR294_002268"
     CDS             1234..2256
                     /locus_tag="KR294_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240343.1"
                     /translation="MVNWEIKKLAKSKSMFISLGILVLILMISIFITPVLETESYYID
                     KEKGRIEDTRSGIDIGNEKFQNKINVLKQFSNQTDTGEFSKKIELMSKKKLDNLSVNE
                     YKDISFWKVFNYRVTNSLINVGMLIIISIIISNIYVDEVVTSVKDIILSSKEKKKALN
                     SKIFVALLVPLVIYSVYLMGIFIITCMQQGVPVNGDLESFRIVDNVVALKTNLSITKY
                     VILNIGIELLMFEGWAMIAIFGSFISKSSISSISFFIFIISITKIMSVIHILPKKLLS
                     VVSNVNYYDLIFGFNKIIGNYLGDIMIFKVNIDIVNIAIGLLMAILIGAMSLCFLVIK
                     SDYISR"
     gene            2270..3157
                     /locus_tag="KR294_002269"
     CDS             2270..3157
                     /locus_tag="KR294_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011948651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0240344.1"
                     /translation="MNKLEIENLSKIYGKKVANDKITVTLENGVYGLLGPNGAGKSTL
                     MKQITTLIKPDEGQILYNGEDIFKMDADYRNILGYLPQEFGVYKNFTAKEFLQYIGAL
                     KGLRGKYLNSKIGELLDLVGLYDVRNKSIGKFSGGMKRRAGIAQVLLNDPKIIVLDEP
                     TAGLDPQERARFRNLIAKMSRDKIIILSTHIISDIESVAKETIMIKDGKLLMKGTHKD
                     ILSHMENKVYNVQVKNECEVDDIQSKYKVVSIQSDINSIVLRIVSEDIPSEDNIQPVQ
                     AKFEDVYMFYFDLEDAREV"
     gene            3163..3936
                     /locus_tag="KR294_002270"
     CDS             3163..3936
                     /locus_tag="KR294_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0240345.1"
                     /translation="MMYLVKAEMIKILKSKSVWIIWLFLIFFGFFLIRKFDVLDTYAD
                     IFYKIEGSIPLIGLIMFIITSGNYIKEYDSNMTGLINTTKKGKKSVVLSKLVANGLIL
                     SIINISFILLVGIRGFSFFDFKNLNESIHNLWYFGNSNLNLTVIQMYIIVILTTIFAS
                     FIFAQIGLTLSSIFKSAVIPFILGGLIMAIPYFSVGFIPDKAIKFMSVTPNWIMMSQQ
                     MVKYNVPSILIVFSIVISIILMIVLTKITYENFTSSKRF"
     gene            4048..4773
                     /locus_tag="KR294_002271"
     CDS             4048..4773
                     /locus_tag="KR294_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012450879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0240346.1"
                     /translation="MENRVLIIDDEVEILKLLETVLKKEGLNNIYTAKTKKEGLELFK
                     SINPDLIVLDIMLPDGEGYDICKEIRKTSNSPIIFLSAKTEELDKLLGLAIGGDDYVT
                     KPFSPKEVAFRVKAHLRRLSYFSDAQNESKNLNNNEEKIISFGPYILNESRAELIKDG
                     KSIGLFAKELKILSLFAHNQNQIISKEKLWDKVWGEDYVGFDNTIMVHIRKIREKLED
                     NPSKPEYILTIKGLGYKLAVKED"
     gene            4777..6180
                     /locus_tag="KR294_002272"
     CDS             4777..6180
                     /locus_tag="KR294_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH0240347.1"
                     /translation="MKWKITRNFIFTIVFVAISVVIINIISILYVISTNSFFKVVDSG
                     NNPEEFARSFEKDLYEKDGEFKLSKIGAEKLEKSNSWIQVLNDLGEEVYGVNVPKDTP
                     KKYTPFQMVNNYKYIETKYVNFVLEKYLNKKHLNIIVGIPSRDISRIILTYSQNNIKK
                     TLNKVIIITLVIDSVVALGVGYLFSRKLTKPISSVLWSIETMANGNYSLYLKDRGIYE
                     EVFKNINMLADTLRVNEVERKENEELREEWLANITHDIKTPLASIQGYAEIINDKDYE
                     FEEDEIQEYTEIIYNKSKYIKDLVDDLNLSTRLKNNTIVLDKKKINLVSLVRDIIIDI
                     LNDNRYKNRNIEFESNEDLIEVYVDSILFRRAITNLIFNSIVHNSEGTLISVEIVKKD
                     NIEIIIKDNGIGISKSDLKHIFKKYYRGTNTGEMHKGSGLGMAISKEIIEIHKGKIYV
                     SSEIGIGTKIIIEIKQN"
     gene            6191..7015
                     /locus_tag="KR294_002273"
     CDS             6191..7015
                     /locus_tag="KR294_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraX"
                     /protein_id="HBH0240348.1"
                     /translation="MDFFKKGISGFTIKILALIFMTFDHIAAFMPQTMQIPIWFHWVG
                     RISAPLFIFMAVEGFYHTSNRKKYISRLYIWSVIMAIGNQIINNVFSHPEGAIIINNI
                     FSTLFLIAIYLQAIEFIKKFRKEKEIKYFIIGLLMIIIPIILGIFTVALLFKVTNRVI
                     ALFMILVPVPFLVEGGPIWIILGIIFYLCRGKKFSLSICYVLMCIFIFTTMSNGDYSL
                     KNSILQNYQWMMIASLPLMLLYNGEKGKSMKYLFYLYYPIHVYILYILGIYLINGF"
     gene            complement(7340..7960)
                     /locus_tag="KR294_002274"
     CDS             complement(7340..7960)
                     /locus_tag="KR294_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBH0240349.1"
                     /translation="MKVLLINGSPNQYGCTYTALNEITKVLSKHDIKTEILYLGKETI
                     PGCISCASCFETGKCIRNDKVNKLIEDLDNIDGIIIGSPVYFSSATGQLTSFLDRLFF
                     IAGSRMATKLGASVVSCRRGGASATFDQLNKYFSISNMPIVSSQYWNQVHGFTPEDVM
                     KDEEGLQTMRTLGENMAWLLKCISAGKKAGIKEPQYEETIMTNFIK"
     gene            8226..8558
                     /locus_tag="KR294_002275"
     CDS             8226..8558
                     /locus_tag="KR294_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0240350.1"
                     /translation="MSIDCISNTDLSETGFSYTLSLISGKYKMIILYCLVEFEVVRYN
                     ALKRYINTISYKTLSLSLKELEADNLIIRTEYPQIPPKVEYSLSERGKSLIPILDAMC
                     EWGERNRP"
     gene            complement(8678..9319)
                     /gene="pcp"
                     /locus_tag="KR294_002276"
     CDS             complement(8678..9319)
                     /gene="pcp"
                     /locus_tag="KR294_002276"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HBH0240351.1"
                     /translation="MKILLTGFDPFGGEPINPAQEAVERVNNNINGAEIIKITIPTVM
                     TKSVEAIDKAIQEHNPDIVISVGQAGGRFDITPERVAINIDDFRIKDNEGNQVIDTII
                     KEDGEPAYFSKLPVKAMVKHMNENKIPASVSNTAGTFVCNHVMYGILYMIDKKYPNIR
                     GGFIHIPYTTSQVIDKKNTPFMSLEEIVKGLELAIEACIIYKEDVKEIGGEIS"
     gene            complement(9340..10272)
                     /locus_tag="KR294_002277"
     CDS             complement(9340..10272)
                     /locus_tag="KR294_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HBH0240352.1"
                     /translation="MQNFINISLEIFYALMGFLMIVIAYKSFTTINNNKKYGTSLFWI
                     LISLPFIFGRLIPANIIGIILILSSLLTLSKQVVFAKYEEPDENFGKEQADKLKNKIF
                     IPSLILAFAAVVVAMSLSNFDNSSQFAIGVGSIIALISALIITKAKPATSVQDGSRLL
                     QQMGPASMLPQLLVALGALFTQAGVGEVISTMISGVVPADSRLFGVIAYVLGMVIFTM
                     IMGNAFAAFSVITAGIGIPFVLSQGGNPAIIGALALTAGYCGTLLTPMAANFNIVPAA
                     LLECKNDYIVIKYQAPVALVLIIAHILVMYFLGF"
     gene            complement(10294..10959)
                     /locus_tag="KR294_002278"
     CDS             complement(10294..10959)
                     /locus_tag="KR294_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HBH0240353.1"
                     /translation="MIKLIGILIVVIGFILKIDTLFTVLLAGVATGIVAGLDFNQIFT
                     ILGDSFVSNRGVSLFILTLPVIGVLERYGLKQRAVSLIEKLKRLTTGKVLTIYMIARQ
                     IAGALSIRMSGHPQFVRPLVNPMAQAAGLSNSDELKESDEEAIKALSAASENYGNFYG
                     QNLFAGSSGVLLIASTLTQFGYNVTGLNIVKASTIMAVIALVVATIQFTLYDKKLNKS
                     HKK"
     gene            complement(11529..12002)
                     /locus_tag="KR294_002279"
     CDS             complement(11529..12002)
                     /locus_tag="KR294_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HBH0240354.1"
                     /translation="MNTIIIYSSKYGCTKDCANILKNKLSDNVTIVDINNNNKIELSK
                     FDKIIIGSSIYVGSVSKKIQVLCNDNVELLNKKQVGIFLCCGFSEQADKYLKSNFPSS
                     LLESANAIGIFGSEARLEKMKFLDKLIMKAVSKGNYDSFRISQDNIDNFLINLNS"
     gene            complement(12005..12409)
                     /locus_tag="KR294_002280"
     CDS             complement(12005..12409)
                     /locus_tag="KR294_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein"
                     /protein_id="HBH0240355.1"
                     /translation="MKIRNKATNKKKKYVKISIALFFVFICIIIVIVSNLKPENLVVK
                     DIDINNVKNGIYTGSADNNLVKATVSVEVNNGKIQNINILKHDHLLGKPAEKITTSII
                     KQQSLDVDAITSATYSSNTIRKAVENALRKGE"
     gene            complement(12384..13013)
                     /locus_tag="KR294_002281"
     CDS             complement(12384..13013)
                     /locus_tag="KR294_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH0240356.1"
                     /translation="MSIKERRKNEKEEMKKKIMDASIEIINQHGYENLSIRKIATKIE
                     YSPTTIYLYYKDKAEIISDMTNKLYNTVESNAIDIMNNCSSLPIDKQIIEIMTSFIKT
                     LSSEPEMAKSIMYSRMNIIFASENTNNTPSNNGIKMLDKFLSIGIEQGIFKKNIDKSS
                     WMLISALLGFVLCVVENKLYSLHNFSQLIENFLDILVGGLYNENSQQGY"
     regulatory      13378..13421
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            13522..14490
                     /locus_tag="KR294_002282"
     CDS             13522..14490
                     /locus_tag="KR294_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside hydrolase"
                     /protein_id="HBH0240357.1"
                     /translation="MEKRKVIIDCDPGIDDSLAILLALNSPELEVIGITTCCGNVPAN
                     IGAENALKTLQMCSSLNIPVYIGEEAPLKRKLVTAQDTHGEDGIGENFYQKVVGAKAK
                     NGAVDFIINTLYNHEKVSIIALAPLTNIAKALIKDKKAFENLDEFVSMGGAFRIHGNC
                     SPVAEFNYWVDPHGADYVYKNLSKKIHMVGLDVTRKIVLTPNIIEFINRLDKKMAKYI
                     TEITRFYIDFHWEQEGIIGCVINDPLAVAYFIDRSICKGFESYVEVVEDGIAMGQSIV
                     DSFNFYKKNPNAIVLNEVDEKKFMYMFLKRLFKGYEDIIDSVEGVI"
     gene            14492..15055
                     /locus_tag="KR294_002283"
     CDS             14492..15055
                     /locus_tag="KR294_002283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBH0240358.1"
                     /translation="MKRKICVKTITLIAFGISINIIGAFIAMGLRLPVYLDSIGTIMI
                     ASLLGPKYAVVTGVFGSLISGITFDVYSLYFAPVQISTGLLAGIAFKKNFLRGLKTPL
                     GVLLFAIPTSIISSIISAFLFGGMTSSGSSYIVQILKVLGLGDVFSVFVTQVFTDYGD
                     KLLAVVLVNLGLNAVPKTLKVSLTGGK"
     gene            15063..15752
                     /locus_tag="KR294_002284"
     CDS             15063..15752
                     /locus_tag="KR294_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBH0240359.1"
                     /translation="MDRYSEITNKNQREIVLLKGFPCIWGKCSFCDYIDDNSNLEEEM
                     NKLNLKVLKNVTGKYGVLEVINSGSCFELPKDTLEKIKCIIKEKNIKKLFLESHWSYK
                     NRLKEMREYFEIPVVFKIGVETFDNDFRNNILNKNANFKTPQDVKEYFDSPCIMVGIK
                     GQTKEMIDKDIEIILNTFEKATVNVFINNSSSIKRDEELVKWFVSKYKFLDENPNIEV
                     LYNNTDFGVGD"
     gene            15879..16607
                     /locus_tag="KR294_002285"
     CDS             15879..16607
                     /locus_tag="KR294_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HBH0240360.1"
                     /translation="MMFDRVKWNKLDYNELLEYMMSIQDIKYRDFNKKLIPGTENIIG
                     IRVPNLRKLSKEISQGNWKEFLEVAEDTYYEEVRLQGMVIGNINSNFEETLYYVKRFI
                     PKIDNWSVCDGFCSDLKSMKKYKENMYDILKKYVYSKNPWEIRFALVMFLIYYVDDKH
                     IKEIFEYCNNIQSEEYYVKMGMAWLLSICFIKCEEETFLYIKNNNLDDFTYNKMLQKI
                     IESNRVDLEKKNIIRSMKRKTRRC"
     gene            16621..17295
                     /locus_tag="KR294_002286"
     CDS             16621..17295
                     /locus_tag="KR294_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBH0240361.1"
                     /translation="MNNNEDRIDKFLELQSKGFKFAEIAQNLKISQSTLRTFLNKKGY
                     KSEKGKYIFKDELNYNKSLDNRNLEEEKAKEYEKSKKNTISNRKKVSTKKKISNEKAL
                     SKSVEQIEFNDTGLKNAKPKQNIKPKKDRKINITQEDLDKLCEVYDWYLEVKDYNIKP
                     KKVSNKKDVHIDDEHIDELKTTRIRIDKEIWNDFERLCSNSNFEKHQILTQALKEFMK
                     KYKNLL"
     gene            17321..18157
                     /locus_tag="KR294_002287"
     CDS             17321..18157
                     /locus_tag="KR294_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240362.1"
                     /translation="MNKIVKKSISLMIILTIFIFMLTACEKDEQPDSVDIQTEDKNEI
                     KIDEGNAKVLNIGKSEIINIDEGDKVDTSTKVENNSTFNISNVELIYNEYDENKKIIS
                     SDSKALLDMTLMPGKVAYIECGHKTFVKGVEVYAYEYEAEGKIVYVNLKENTINIRNN
                     NIKLENSSQYEVLSTSELKKVNESNEGITYQVKVKNSSSKDLGNIILKTAEVNENGEY
                     LTVNRVPSYKILKPSEETDIDILCSTKAKSVEIVGYTYDDIKEKANVDIDLKSHKVKI
                     DK"
     gene            18173..18844
                     /locus_tag="KR294_002288"
     CDS             18173..18844
                     /locus_tag="KR294_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0240363.1"
                     /translation="MKVLIVEDNKILLESVVEELSKHFETEKCEDGEEALYLVNQNIY
                     DLVILDLMLPNINGFDILKKMRVNNIDTPVLILTAKETLDDKVEAFTIGANDYLTKPF
                     YMEELVARVYAILRTNGKIKERNGLEFKSLYLDTLEKRVYIEKEEIKLQNKQFNLLEY
                     FVLNKGSILLKEQIYDRIWGIDSDATIEIVEVYVSNLRKKLSKYGYDKYIKTKRKVGY
                     IFDDK"
     gene            18834..20066
                     /locus_tag="KR294_002289"
     CDS             18834..20066
                     /locus_tag="KR294_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH0240364.1"
                     /translation="MINKNVFTSTKNHLIKMYIIVVGSFLIIFSIFIYSYFRGLTYSG
                     IDSEINDELEYIVSQFKRTSFLNPIRLKDPKDMVYVYEDGRISYYTQNEYFDELLPDR
                     RLDKKNSFFKYTENGYTFRELNVDVGRYQIQIIRNIDSEMNSLRQLTSVLIIGILISV
                     IITYFVAVYLTRKALIPIETAWKNQAKFIQDASHELRTPITIVSSKLESMLKSPESTV
                     NDEVETIATAMKETRRLKKMITDLLSLTKEDSIVKVNLEEIDLEKLLEEISEDYIDIA
                     EFQEKRFVFNSKLKNKVIITDKNKLRQLILIFIDNAFKYTKLGDEIALELKEDIEDEV
                     TLLISDTGIGIKKEEIPLIFDRFFRSENVRNKDLEGSGIGLSIARMISLNLSIDINVT
                     SDVDIGTTFELSIPKKLK"
     gene            20216..20533
                     /gene="trxA"
                     /locus_tag="KR294_002290"
     CDS             20216..20533
                     /gene="trxA"
                     /locus_tag="KR294_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HBH0240365.1"
                     /translation="MAKVINTSEFRSSVEGSKGVVVVDFFATWCGPCNMLGPVFAELG
                     EEMKDKARFVKVDIDESLEIAQQFNVSTVPTMIIFKDGKPVETLIGFMPKNKIEMQVK
                     SYL"
     gene            20550..21428
                     /locus_tag="KR294_002291"
     CDS             20550..21428
                     /locus_tag="KR294_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBH0240366.1"
                     /translation="MRYDIAIIGSGPAGLSAAINAKIRNKTIIMFGNDNLSNKLVKAP
                     SIDNYLGFYDISGDELKDKFKSHIDSMDISIENKRINNIYAMGEYFTIMSGNDMYEAT
                     TVILATGVEYTRPIKGEEEFLGRGVGYCATCDAPLYRNKKVAVIGYNEESKEEANFLS
                     ELTSKTYFIPMYKKDNLMRSSDNLDDSIEVIHDRPVQIDGDKLVNKVSFKENHIEVDG
                     VFVIKDSTAPSALVPGIEIDGIHIKVDNNMKTSIDGCFAAGDCVGKPYSYIKAAGQGQ
                     IAALNAVYYLDKLKRA"
     gene            21698..22066
                     /locus_tag="KR294_002292"
     CDS             21698..22066
                     /locus_tag="KR294_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBH0240367.1"
                     /translation="MENLVKIFKALSDETRLNILILVSKRNICQKGISKYLGISDSAV
                     SQHIKILKDVGIITGYKEGYYVLYHINKESFNICVDFINSMLSNSSESFIDVFDVNTI
                     HLGCSKECKSIKKCCKRREK"
     gene            22069..22440
                     /locus_tag="KR294_002293"
     CDS             22069..22440
                     /locus_tag="KR294_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NifB/NifX family molybdenum-iron cluster-binding
                     protein"
                     /protein_id="HBH0240368.1"
                     /translation="MKVCIPVEENKGLDSKPYGHFGSAPIFVVCDLESGEVKSLDNGD
                     LDHEHGKCQPLKALSGTAVDAVVVGGIGQGAIIKLNGMGIKVYRAEGDTISANLDLLK
                     NGKLVEFPSDHTCSHDGCGHH"
     gene            complement(22585..23040)
                     /locus_tag="KR294_002294"
     CDS             complement(22585..23040)
                     /locus_tag="KR294_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240369.1"
                     /translation="MNINTVQGDSIEVLLRQLGATRISKVSSTLYFIKFDLGDGWEIS
                     YTYNINAKDQYFLQRIEPYPIGRGLFNDEYEIVSFISKDLKKFLNAKNSSNFKTFVEV
                     TRKVNSIIDNVEELFLNYNVDGDDLKTLNKELNDILNDIDYIEKHTKKI"
     gene            complement(23079..24344)
                     /locus_tag="KR294_002295"
     CDS             complement(23079..24344)
                     /locus_tag="KR294_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsB/NhaD family transporter"
                     /protein_id="HBH0240370.1"
                     /translation="MEFQQIIAICIFLIVMAAIITEKVNRSVAAVGGALLMIIFNILT
                     LDEGLSHIDFNTIGVLVGMMLFVAVVKNSGLFEYIAIWTAKKAKGDPWKIMICFAIIT
                     AILSAVLDNVTTVLLIGPMTIVITQILGLNPVPFLITQILASNIGGTATLIGDPPNIM
                     IGSAANLSFMDFVINLGPAVIVILAITIICFRFIYGKELVVNERAKNAILKLDEKKSV
                     KDKPLLIKSLILIAFILFGFMFHSTIHIDSSVVALTGASIMLLIGKQDVDEIMAGIEW
                     STILFFMGLFVVVGGLVEVGIINKLAQALIGLTEGHLVFTMLLILWLSAIVSSFLDNI
                     PFVATLIPLILTMQAEGIDVMPLWWATSLGACLGGNGTLIGASANVVLAGIGNKHGHP
                     ISFKEYFKIGFPLMIISIIISTVYLIIKF"
BASE COUNT         9471 a         2713 c         3780 g         8562 t
ORIGIN      
        1 tataaacaaa aaataaaaaa cttatataaa taaaatgctt gtttttcttg tattatttat
       61 ataaatattg aaatttgtct agttatacgt ttttattgac cagttatgca gttgatattg
      121 aatattctaa atattggtgt tattttatag gtggtttaaa catattaggg ggattttata
      181 tatgatttgt atgatttata gagaatgtat aaaatagtaa aggtttagag ccatgtttag
      241 tggattgcag aatatgcata tagaatgatt cttgtaaatt aagttagaca taggaaatat
      301 ataatttgta ttggatgatt aattttatgg tgtatgcttt taacttctat aatgggaaag
      361 taaagatgta ctcccaatac atctttactt tagcagaagt tatagttact tataaagtac
      421 aaaaaattat atatttatta gagtagataa atctaaaaag gtttttctag aaaaatttag
      481 ttttaattgt atctacttac taataataag acttgatgta agcaggtttc aactaccgtt
      541 tctccatatt ctgatataaa atcatctaac tgtgtatcta aaaaattaca ataatcatat
      601 gaactactga tgtaagcagt tagtatatgt gtacatttgt ctatttctcc aataaacata
      661 ttatccatcc ccctaaaaaa tttagtaaaa ataaaaagtc gcattctatt agtcaattaa
      721 cataatttat aaaatttttt agtactagtt tctataactt aactccttaa ggttaaatat
      781 tcccagtttt accaatttag ttttattcta caagtatata atactagaag atgcttcatt
      841 attcaacatg cttgtttgag aatagaaaat attctaaaat tataattgtt tttaaaaata
      901 agattcaaga taaataaagt tatatgcaac tatttaataa tctttccata ataaggacag
      961 taggttctat tcttaaaaaa ctccatcttt aaatttaaag aataactaca atttgaacaa
     1021 caataaaatt tccaatcaat aaaaatatca aaaataataa aaataattga aaatgtataa
     1081 tttcccagaa aaataataaa tgtaactcca ataataaaca cacctataaa ttataaaata
     1141 atttaagctt tatttaaggt tagtattata tttatataag atttaagttt taatatatat
     1201 gtgtaattaa aatgatttag gaggagaaat atattggtaa attgggaaat aaaaaaattg
     1261 gctaaatcta agagtatgtt tatatctcta ggcatattag tgttaatact aatgattagt
     1321 atctttatta cgcctgtttt agaaacagaa agttattata tagataaaga aaaaggacgt
     1381 atagaagata cgagaagtgg tatcgacata ggtaatgaga aatttcaaaa taagattaat
     1441 gttttaaagc agttttcaaa tcaaacagat acaggtgaat tttctaaaaa aattgaatta
     1501 atgtcaaaga aaaaacttga taatctaagt gtgaatgaat ataaggatat tagtttttgg
     1561 aaagtattta actatagagt tacaaattca cttataaatg taggaatgtt aatcattata
     1621 tctataatta tatctaatat ttacgtagat gaagtcgtta cttcggtaaa agatatcata
     1681 ctatcatcaa aagagaagaa aaaagcatta aattctaaaa tatttgttgc tttattagtt
     1741 ccattagtaa tttattctgt ttatttaatg ggaatattta ttataacttg tatgcaacaa
     1801 ggagtacctg ttaatggaga cttagaatct tttagaatag tagacaatgt agttgcattg
     1861 aaaactaatt taagtataac aaagtatgta atattaaata taggcataga gcttttgatg
     1921 tttgaaggat gggccatgat agccatattt gggtctttta taagtaagtc ttcaatatct
     1981 tcaataagtt tttttatatt tattatatct ataactaaga taatgtcggt aatccatata
     2041 ttacctaaaa aattactttc agttgtatca aatgtaaatt attatgattt gatatttggt
     2101 tttaataaaa taataggaaa ttatctaggt gatattatga tatttaaagt gaatatagac
     2161 attgtcaata tagcaatagg acttttgatg gcaatattga taggtgctat gtcattatgt
     2221 tttttagtaa taaaatcaga ttatataagt agataaaagg ggagttaaga tgaataaatt
     2281 agaaatagaa aatctttcaa agatatatgg taaaaaagta gcaaacgaca agattacagt
     2341 aactctagaa aatggagttt atggtcttct aggaccaaat ggagcaggaa aatctacatt
     2401 aatgaaacaa ataacaacgt tgataaaacc tgatgaaggt cagatacttt ataatggtga
     2461 ggatatattt aaaatggatg ctgattatag aaatatttta ggatatttgc cacaagaatt
     2521 tggagtttat aaaaatttta cagcaaaaga atttttacag tatattggag ctttaaaagg
     2581 tttaagggga aaatatttaa atagtaagat aggagaatta ttagatttag taggtcttta
     2641 tgatgtgaga aataagtcta taggaaaatt ttcaggaggt atgaagagga gagctgggat
     2701 agcacaagtt ttactaaacg accctaagat aatagtcctt gatgagccaa cagcaggtct
     2761 tgacccacaa gaaagagcta gatttaggaa tttaatagca aaaatgtcta gagataagat
     2821 aataatactt tctactcata taatttccga tatagaatca gttgcaaagg aaacaataat
     2881 gattaaagat ggcaaactcc taatgaaagg aacacacaaa gacatattaa gtcacatgga
     2941 aaataaagta tataatgttc aagttaaaaa tgaatgtgaa gttgatgata tacaatctaa
     3001 atataaggtt gtaagtattc aaagtgatat taattcaata gtacttagaa ttgtttcaga
     3061 ggatattcca agcgaggata atatacaacc agttcaagca aaattcgaag atgtatacat
     3121 gttttatttt gatttagaag atgcaaggga ggtgtagtag aaatgatgta tttagttaaa
     3181 gctgaaatga taaaaatatt aaaatcaaag agtgtttgga taatttggct gtttttaata
     3241 ttttttggat tttttctgat tagaaagttt gatgttttag atacttatgc agatatattt
     3301 tacaagatag aaggctcaat acctctaata ggtttgataa tgtttataat aacttctgga
     3361 aattacatta aagaatatga ttctaatatg acaggtttaa taaatacaac taaaaaggga
     3421 aaaaaatcag tagtattatc aaaactagta gctaatggat taattttatc tattattaat
     3481 atttctttta tattgttagt aggaattaga ggttttagtt tttttgattt taaaaattta
     3541 aatgaatcga ttcataactt atggtacttt ggaaatagta atttaaatct tacagtaata
     3601 caaatgtata taattgttat attgactact atttttgctt cttttatatt tgcacaaata
     3661 ggcttaacac tttcatctat atttaaatcg gctgtaattc catttatact aggtggattg
     3721 ataatggcaa ttccatactt tagtgtaggt tttataccag ataaagctat aaaatttatg
     3781 tcagtgactc caaattggat tatgatgagc caacaaatgg ttaagtataa tgtaccaagt
     3841 attttgatag ttttttctat agtaatctca attatattaa tgatagtgtt aactaaaata
     3901 acatatgaaa attttacatc aagcaaaagg ttttaactaa aaataatagt aattttattt
     3961 atattttagt ttaattaaaa ataagataaa tgaattttag ataaaatata tgctaatata
     4021 tatgtaaatt attacaggag gttgtttatg gaaaatcgtg ttttaataat agatgatgaa
     4081 gtagaaatat tgaagctttt agaaactgtc ctaaaaaaag aaggccttaa taatatatat
     4141 actgcaaaaa ctaaaaaaga aggattagaa ttatttaaaa gtattaatcc tgatttgatt
     4201 gtattggata ttatgttacc agatggcgaa ggttatgata tttgtaaaga aataagaaaa
     4261 acctccaatt ctccaataat atttttatca gctaaaaccg aagaattaga taagttactt
     4321 ggactagcga ttggaggaga tgattatgtt acaaaacctt ttagccctaa ggaagtggct
     4381 tttagagtta aagcgcattt gagaagatta agttatttta gtgatgctca aaacgaaagt
     4441 aaaaatctaa ataataatga agaaaaaatt atatcatttg gcccatatat attaaatgaa
     4501 agtagggcag aacttataaa agatggaaaa tctataggac tgtttgcaaa ggaactaaaa
     4561 atcctatctt tatttgcaca taatcaaaat caaattataa gtaaagaaaa actatgggat
     4621 aaagtgtggg gagaagatta tgttggattt gacaatacta taatggttca tataagaaaa
     4681 attagggaaa aattagagga taatccttca aaacctgaat atattctgac aataaaaggt
     4741 cttggatata aattagcagt aaaggaagat tagaatatga agtggaagat tactagaaat
     4801 tttatattta caattgtgtt tgtagctata tcagtagtaa ttataaatat catatctata
     4861 ttgtatgtga tttcaactaa tagctttttt aaagttgtag attctggaaa taatcctgaa
     4921 gaatttgcac gttcttttga aaaagattta tatgaaaaag atggagaatt taaactatct
     4981 aagattggag ctgaaaaatt agaaaaatca aattcctgga tacaggtttt aaatgattta
     5041 ggagaggaag tttatggagt aaatgtgcca aaggatactc caaaaaaata tacacccttt
     5101 caaatggtga ataattacaa gtatatagaa acaaagtatg ttaattttgt actagaaaaa
     5161 tatttaaaca aaaaacattt aaacataata gtaggtatac ctagtagaga tatatcaaga
     5221 ataattttaa cctattctca aaataacatt aaaaaaactt taaataaagt tatcattata
     5281 acactagtaa ttgatagcgt ggtagcttta ggtgtaggat atttatttag tagaaaactt
     5341 acaaaaccaa tttcaagcgt actatggagt attgagacta tggctaatgg aaattatagt
     5401 ttatatctta aggacagagg tatatatgaa gaagttttta aaaatataaa tatgttagct
     5461 gatactttaa gagtaaatga agttgagaga aaagaaaatg aagagttgag agaggaatgg
     5521 ctggcaaata taacacatga tataaagaca cctctagcat ctatacaagg gtatgcagag
     5581 ataattaatg acaaagatta tgagtttgaa gaagatgaaa tacaagagta tacagaaatt
     5641 atatataata agtctaagta tataaaagat ttagttgatg atttaaattt atctactcga
     5701 ttaaaaaata atactatagt tctggacaag aaaaaaataa atttagtcag tttagtcaga
     5761 gatataataa ttgatatttt aaatgataat agatataaaa ataggaatat tgaatttgaa
     5821 agtaatgaag atttaattga agtatatgta gattcaatct tattcagaag ggctataacc
     5881 aatcttatat ttaattcaat agttcataat agcgaaggaa ctttgataag tgtagaaatt
     5941 gtaaaaaaag ataatataga aattataata aaagataatg gaattggaat aagcaaaagt
     6001 gatttgaaac atatttttaa aaaatattat agaggtacta atacaggtga gatgcataaa
     6061 ggttcaggtc ttggtatggc tatttctaaa gaaataatag agattcataa aggtaaaatt
     6121 tatgtaagta gtgaaattgg aataggaaca aaaattatta tagagataaa acaaaattag
     6181 gagatatgat atggattttt ttaaaaaagg tataagtggg tttactatta aaattttagc
     6241 attaatattt atgacatttg accatatagc agcatttatg ccacaaacaa tgcaaatacc
     6301 aatttggttt cattgggtag gcagaatatc agcaccactg tttatattca tggctgttga
     6361 aggattttat cacactagta acagaaaaaa atatataagt agattgtata tttggtctgt
     6421 tattatggct ataggaaatc aaataattaa taatgtattt tcacatccag aaggagctat
     6481 aattataaat aacatttttt caacattatt tttaatagcg atttatttac aagcaataga
     6541 gttcataaag aaatttagaa aagagaaaga aattaaatat tttattatag gattattgat
     6601 gataatcatt cctataattt taggaatatt tacagtagct ttacttttta aagtcactaa
     6661 cagagttatt gctttattta tgattttggt accagtacca tttttagtag aaggtggacc
     6721 aatttggatt atacttggga ttatttttta tttgtgtaga ggtaaaaagt tcagtttgag
     6781 tatttgttat gttttaatgt gtatatttat atttacaaca atgtcaaatg gagattatag
     6841 tttaaaaaat tctattttac aaaattacca atggatgatg attgcttctc tacctttaat
     6901 gttactttac aatggagaaa aagggaagag tatgaagtat ttattttatt tatactatcc
     6961 aatccatgta tatatattgt atatcttagg aatatactta ataaatggtt tttgattgta
     7021 agtgatattt ttaatacaaa atgaacagta tgaggattgt tttaggtcta ttaaaattgt
     7081 tatttagatg agatttgtag aatatttaaa tttatgagca gaaattcagt tattgtaatt
     7141 tcaataacat tagaatataa tattataatt tatttagaaa tatatgatgt tatacatggt
     7201 ttggttatta atgtaataat aaaacagagg tttgatataa aattcaatac ctctgtttta
     7261 gtgcttttta tcctacattt atgcttattt tatttataaa ttagtgtttt gttttaatta
     7321 atattagtac attttttatt tattttataa aattagtcat aattgtttct tcatattgtg
     7381 gttctttaat tccagctttt ttacctgctg atatacactt aagaagccat gccatgtttt
     7441 ctcctagagt tcgcatagtc tgtaatcctt cttcatcctt cataacatcc tctggagtaa
     7501 agccatgtac ctggttccaa tactgtgatg atacaatagg catattgctg attgaaaaat
     7561 atttatttag ttggtcaaat gttgcacttg caccaccacg tctacatgac acaactgaag
     7621 cacctaattt tgtagccatg cgacttccag ctatgaaaaa tagacggtca agaaaagaag
     7681 ttaattgacc agttgcacta gaaaagtaaa caggagaacc aataataata ccatcaatat
     7741 tatccagatc ttcaatcaat ttattaactt tatcatttcg aatacatttt ccagtttcaa
     7801 aacaggatgc gcaactaata catcctggga ttgtttcttt acctaaatac agtatttctg
     7861 ttttaatatc gtgtttactc aatactttag taatctcatt tagtgctgta taagtacatc
     7921 catattggtt tgggctaccg tttatcaata aaactttcat tataaatttc ctccaatgaa
     7981 ttttatttaa tagattttct aagagatatt attttttata aaataggatt ttcatgaata
     8041 ttatcaattt atatagaaat gtctaatctt agaatcctat ttaaaataac ttttttttta
     8101 gtaaatacac ctcctattat aaaattgact ttcaattatt cttacactat aattttatta
     8161 taaattattc taaaaacaag tacgcacatt tttgttcaat actaaccaaa aggagagtgt
     8221 aatatatgag tatagactgt atatcaaata cagatttaag tgaaacagga tttagttata
     8281 cactttcact gattagtggt aaatataaga tgataattct ttactgtctt gtagaatttg
     8341 aagttgtaag atataatgca ttaaaacgtt atataaatac tatctcctat aaaactttga
     8401 gtttatcatt aaaagaatta gaagcagata acttgattat tcgtactgaa tatcctcaaa
     8461 tacctcctaa ggtagaatat agtctatcag aaaggggaaa atctctgatt ccaattttag
     8521 atgcaatgtg tgagtgggga gagaggaata gaccttaatt ttgtatctgt agataccata
     8581 aaaagactgt gagtaaaatt gtttgaataa tctactcaca gtctatattt aaattaatag
     8641 ttagtatttt taatttataa aaatactaaa aaatttatta tgaaatttca ccaccaattt
     8701 cttttacatc ttctttatat ataatacaag cttctatagc taattctaag ccttttacta
     8761 tttcttctaa agacatgaat ggtgtatttt ttttatctat tacttgtgaa gttgtatatg
     8821 ggatgtgtat aaatccaccc cttatattag gatatttctt gtctatcata taaagaattc
     8881 catacatcac atgattgcaa acaaatgttc ctgcagtgtt tgaaacacta gctggaattt
     8941 tattttcatt catatgtttt accatagctt ttacaggcaa ttttgaaaaa tatgcaggtt
     9001 caccatcttc ttttataata gtatctataa cctggttacc ctcattatct tttattctaa
     9061 aatcatctat atttatagca actctctcag gtgtaatgtc aaatctacct ccagcttgtc
     9121 caactgatat tactatatct ggattgtgct cttgaatagc tttatctata gcttcaacag
     9181 attttgtcat aactgttggt atagttatct ttatgatttc tgcaccgttt atattattat
     9241 tgaccctttc aactgcttct tgagctgggt ttattggttc tccaccaaat gggtcaaatc
     9301 ctgttaacaa aattttcatt attttacctc ctaattatat taaaatccta aaaagtacat
     9361 tactaatatg tgggctataa ttaataccaa agcaactgga gcttgatatt ttataacaat
     9421 ataatcattt ttacattcta gcaaggctgc tggaactata ttaaaattag cagccattgg
     9481 agtaagtaga gttccacaat atcctgctgt taatgctaat gctccaatta tagcaggatt
     9541 tccaccttga gacaatacaa aaggaatacc aattcctgcc gttatgactg aaaatgcggc
     9601 aaatgcattt cccattatca tggtaaatat aaccatacct aatacataag ctataacacc
     9661 aaataatctg ctatcagcag ggactacacc agatatcatg gttgaaataa cttcaccgac
     9721 tccggcttga gtaaataaag ctcccaatgc aactaaaagt tgtggtaaca tactagcagg
     9781 tcccatttgt tgaagtaatc ttgagccatc ttgaactgat gtagcaggtt ttgccttagt
     9841 tattataagg gctgatatta atgcaattat tgaacccaca cctattgcaa attgagaaga
     9901 attatcaaaa ttagaaaggc tcatagctac tactactgca gcaaatgcta atattaatga
     9961 tggtataaat attttatttt taagtttgtc tgcttgttct tttccaaaat tttcatctgg
    10021 ttcttcatac tttgcaaata caacttgttt agaaagtgtt aataaactag ataatattaa
    10081 tattattcct attatattgg ctggaatcaa tctaccaaat atgaatggca gtgatataag
    10141 tatccaaaat aatgatgtac catatttctt attgttattt atggtagtaa aagacttata
    10201 tgctataaca atcattaaaa atcccattag tgcgtaaaag atttctaatg atatgtttat
    10261 aaaattttgc atttttattc ctcctaaata aaactatttt ttatgacttt tgtttaattt
    10321 tttatcatat aaggtaaact ggattgtagc cactacaagt gctattactg ccataatagt
    10381 actagccttt acgatattaa gtccagttac attgtatcca aattgagtca gagtagatgc
    10441 tataagtaat actccactac tacctgcaaa taagttttga ccataaaaat ttccatagtt
    10501 ttctgatgca gcagataatg cctttatggc ttcttcatcc gattctttta gttcatcact
    10561 attacttaaa ccagcagctt gtgccatagg attaacaagt ggtcttacaa attgaggatg
    10621 tccactcatt cttattgata gagcaccagc tatttgtcta gctatcatgt atatagtaag
    10681 tacttttcct gttgtaagtc tttttaattt ttctattaaa gaaacagctc tttgttttaa
    10741 accatatctt tctaatacac cgattactgg caatgttaat atgaataatg atacacctct
    10801 gtttgagaca aaagaatctc ctaaaattgt aaaaatttga ttaaaatcta atcctgcaac
    10861 aattcctgtt gccactcctg ctaataatac agtaaataat gtgtcaattt taagtataaa
    10921 tccaattaca actatcaata taccgattag ttttatcata aattgttctc cttccatttc
    10981 tatatgtttt aatttaaatt tatttaatgg ataaagttaa actcttttta tagtatttgc
    11041 gttaatagga ctattattat aaaatttaat aaaaaatagg gaagatgttt taaagtatca
    11101 aagtaaataa tggttgtgta taggaatttg aataacaaag attatatttt aagctaatat
    11161 gaattgattt tgtaagtcta tagtttaagt atatgtcaat atttgaaata ggttttaaat
    11221 tagatattat attataaaaa gagaatgtgc caaacataga gacaagtgta tttttcactt
    11281 ttgaaatgat aaaaatatat ttgatttcat acaaaaagag agtgtctaat gaatttttta
    11341 gttcattaga cactctcttt ttgttatgat taataaaaca tatttgttat gattaataaa
    11401 gcatatatta agtgctagtt tcattagatt tcactaagaa aaataaaatt ttgataaagt
    11461 ttaaagacta ttttgagcaa tattacttat aaataaaaga atttatcata gaaataatta
    11521 gttttatttt agctattaag atttattaaa aaattatcta tattatcctg tgatattcta
    11581 aaactgtcat aattaccttt tgaaacagcc ttcataataa gtttatctaa aaatttcatt
    11641 ttttctaatc gagcttcact accaaaaatt ccaatagcat ttgcactttc taataaggat
    11701 gatggaaaat ttgattttaa atatttatct gcttgttcag aaaagccaca gcaaaggaaa
    11761 atgccaactt gttttttgtt taataactct acattatcat tacatagcac ttgtattttt
    11821 tttgaaactg aaccaacata tatagaactt ccaataataa ttttatcaaa ttttgataac
    11881 tcaattttat tattattatt aatatcaaca atagtgacat tatctgatag tttatttttt
    11941 agtatatttg cacagtcttt tgtacaacca tatttacttg aatatataat aatagtattc
    12001 ataattattc tccctttctt aaagcatttt ctacagcttt tcgtatagta ttactgctat
    12061 aagttgcaga agttatagca tccacatcta aagactgttg tttaataata cttgttgtaa
    12121 ttttttcagc aggtttacct aaaagatggt cgtgttttaa gatattaata ttttggattt
    12181 taccattatt aacttcaaca gacacagtag cttttaccaa gttattatca gcacttccag
    12241 tataaatgcc atttttaaca ttattaatat ctatatcttt tactaccaag ttttctggct
    12301 ttaagttgct tacaattaca ataataatgc atataaatac aaagaataga gcaatagata
    12361 tttttacata ttttttcttt ttattagtag ccttgttgcg aattttcatt gtaaagtcct
    12421 cccactaaaa tatctaagaa attttctata agttgagaaa aattatgtaa agaatatagt
    12481 ttattttcaa caacacataa aacgaatcct aacaatgcac ttataagcat ccatgagctt
    12541 ttatctatat tttttttgaa tattccttgt tcaattccaa tggaaaggaa tttatcaagc
    12601 atttttatac cattattgct aggcgtattg tttgtatttt cagatgcaaa tataatattc
    12661 attctactat acatgataga ttttgccatc tctggttcac tagaaagagt ttttataaag
    12721 ctagtcataa tttctatgat ttgtttatct attggtagtg atgagcaatt attcataatg
    12781 tcaatggcat tactttctac tgtgttataa agtttattgg tcatatcgct gataatctct
    12841 gctttgtctt tgtagtaaag ataaattgta gttggagaat attctatttt tgtagcaatt
    12901 tttcttattg ataaattttc atatccatgt tggtttataa tttcgatgct agcatccata
    12961 atctttttct tcatttcttc tttttcattt ttacgtcttt ctttgatact catataatca
    13021 cctctttgct taacggtgtt aagttaattt acactgttat tgtataattt aattttaata
    13081 ctgtcaataa attattaaat aatataagtt aatatatttt tatggataat aaattaatgt
    13141 tattaattgt aatatttaag atattattgt ataataataa tcggtttaaa tgcgccacat
    13201 cttattaaag ttggttcata attctaaata aactttaata agatacatta aaatataata
    13261 aattctttta tgctataaaa tttattttat agctattaaa tcagatgttt aaaaattttt
    13321 taacagtcta tagtttttaa gagtctatag taagtagcct aaaaatatga ttttacatct
    13381 gtacttgttc gagaactcca agtataaaaa actaaggaat tatatagtgg cagtatataa
    13441 ttaataccct tagacacacc tttttgaaag tggaaaaaag atgtgtagtt ctcctcgacc
    13501 acaaatcaag gaggataaaa aatggaaaag agaaaagtaa taattgattg tgacccagga
    13561 attgatgatt ctttggcaat tcttctggct ttaaactcac cagagctaga agtaattgga
    13621 attaccacat gttgtggaaa tgttccagca aatataggtg cagaaaatgc actaaaaaca
    13681 cttcaaatgt gttcttcact aaatattcca gtatatatag gagaagaagc accactaaaa
    13741 agaaaacttg taacagctca agatacacat ggagaagatg gtattggaga aaacttttat
    13801 caaaaggttg taggagctaa agcaaaaaat ggagcagtgg attttataat aaatacttta
    13861 tataatcatg aaaaagtatc aataatagca cttgcaccac ttacaaatat agctaaagca
    13921 cttattaaag ataagaaagc atttgaaaat ctcgatgagt ttgtatctat gggaggagca
    13981 tttaggattc atggaaattg ctctccagta gcagagttta attattgggt agacccacat
    14041 ggagcagatt atgtttacaa gaatttatct aaaaaaatcc acatggtagg tttagatgta
    14101 actagaaaaa ttgtacttac tcctaatatt attgagttta taaatagact tgataagaag
    14161 atggcaaagt atataactga aataactaga ttttatattg atttccattg ggaacaggag
    14221 ggaataattg gctgtgtgat aaatgaccct ctagcagtag cgtactttat agatagaagt
    14281 atatgtaaag gatttgaatc atatgtagaa gttgtagaag atggaatagc tatgggtcag
    14341 tctatagtgg attctttcaa tttctataaa aaaaatccta atgcaattgt tctaaatgaa
    14401 gttgatgaga agaaatttat gtacatgttt ttaaagaggc tttttaaagg ttatgaagac
    14461 attatagact ctgtggaagg agtgatatag tgtgaaaaga aaaatatgtg taaaaactat
    14521 tacacttata gcttttggta tttctataaa tataataggc gcttttatag ctatgggatt
    14581 aagattacct gtatacttag attcaatagg aactataatg atagcttcac ttttaggacc
    14641 taaatacgct gttgttacag gtgtgtttgg aagtttaata agtggaatta cgtttgatgt
    14701 gtattctctc tattttgcac cagttcaaat atcaaccgga ttacttgctg gaatagcatt
    14761 taaaaagaat tttttaaggg gtttaaaaac tccactagga gtacttttat ttgccattcc
    14821 aacatctata ataagttcaa taatttcagc atttttattt ggaggtatga cctcttcagg
    14881 ttcatcatat atagtgcaaa tcttgaaagt gttaggactg ggggatgttt ttagtgtgtt
    14941 tgtaacccaa gtatttactg attatggaga taagctgtta gcagttgttt tagtgaattt
    15001 aggattaaat gcagttccaa aaactttaaa ggtatcattg actggaggaa aatagataga
    15061 aaatggatag atatagtgag ataacaaata aaaatcaaag agaaattgtt ctgcttaaag
    15121 gatttccttg tatatgggga aagtgttctt tttgtgatta tatagatgat aattctaatt
    15181 tagaagaaga gatgaataaa ttaaatctaa aggttttaaa aaacgtaact gggaaatatg
    15241 gagttcttga agtcataaat tctggaagct gttttgaatt acctaaggat actttagaaa
    15301 aaataaagtg tattataaaa gagaaaaata taaaaaaatt atttttagaa agtcattggt
    15361 cttacaaaaa taggcttaag gaaatgagag agtattttga aattcctgtg gtatttaaaa
    15421 ttggagttga aacctttgac aatgatttta gaaataatat tttaaataaa aatgcaaatt
    15481 ttaagactcc acaagatgta aaagaatatt ttgattcacc ttgtattatg gttggaataa
    15541 aaggacaaac aaaagagatg atagataaag atatagagat tatcctaaat acttttgaaa
    15601 aagcgacagt gaatgttttt ataaataatt cttctagtat aaaaagagat gaagagttag
    15661 tgaaatggtt tgttagtaag tataaattct tggatgaaaa tccaaatata gaagttttat
    15721 acaataatac agattttggt gtaggagatt agcattaatt tagtttaaat ttaaaattga
    15781 aaagtttctt atgtttttga aaaagcttct aatagttaga agcttttttt gtagagtttt
    15841 atgttacaat aagaaaaaag gaattaagga gcaattaaat gatgtttgat agggtaaaat
    15901 ggaataaatt ggattataat gaacttttag aatatatgat gtctatacaa gatataaaat
    15961 atagagattt taataaaaag cttatacctg gaacagaaaa tataataggt attagagttc
    16021 ctaatttaag aaagttatca aaagaaataa gccaagggaa ttggaaggaa tttttagaag
    16081 tagcagagga tacatactat gaagaagtta ggctacaagg tatggtaatt ggcaatataa
    16141 atagtaattt tgaagaaact ttatactatg taaaaagatt tatacctaaa atcgataatt
    16201 ggtcagtttg cgatggattt tgttctgatt taaagtctat gaaaaaatat aaagaaaata
    16261 tgtatgatat acttaaaaaa tatgtttatt caaagaatcc atgggaaatt agatttgcat
    16321 tagttatgtt tttaatatat tatgttgatg ataaacatat taaagaaata tttgaatact
    16381 gtaataatat acaaagtgaa gaatattatg ttaaaatggg tatggcatgg ttgctatcaa
    16441 tttgttttat taaatgtgaa gaggaaactt ttctctatat aaaaaataat aatttagatg
    16501 atttcactta taataaaatg ctacaaaaaa taattgaatc aaatagagta gatttagaaa
    16561 agaagaatat aataagaagt atgaaaagaa agacaagaag atgttgacgg aggaatatta
    16621 atgaataaca atgaagacag aattgacaaa tttttagaac ttcaaagcaa aggatttaaa
    16681 tttgcagaga tagctcaaaa tctaaagatt agtcaaagta ctttaagaac ttttttaaat
    16741 aaaaaaggat ataagtcaga aaaaggtaaa tacatattta aagacgaatt aaattataat
    16801 aaaagtttgg ataatagaaa cttggaagaa gagaaagcta aggagtatga aaaaagtaaa
    16861 aagaatacta taagtaatag aaaaaaagta agcaccaaaa aaaagatttc taatgaaaag
    16921 gctttaagta aaagtgttga acaaattgag tttaatgata caggtttaaa aaatgcaaag
    16981 ccaaaacaaa atattaagcc taagaaagat agaaaaataa atataactca agaagattta
    17041 gataagcttt gtgaagtata tgattggtat ttagaagtaa aagattacaa tataaagcct
    17101 aaaaaagtat ctaataaaaa agatgtacat atagatgatg aacacataga tgaattaaaa
    17161 acaacaagaa tacgtataga taaagaaata tggaatgatt ttgaaagatt atgtagtaat
    17221 tcgaattttg aaaaacatca aatacttaca caggcattga aagaatttat gaaaaagtat
    17281 aaaaatctac tataaaatac tactatatga ggtgcttaat atgaataaaa tagtaaaaaa
    17341 atcaatttct ctaatgatta tattaacaat atttattttt atgttgacag catgtgaaaa
    17401 agatgaacag cctgattcag ttgatattca aacagaagat aaaaatgaga taaaaataga
    17461 tgagggaaat gcaaaagtat tgaatatagg aaaatcagaa attataaata tagatgaagg
    17521 tgataaagta gatacatcaa caaaggtaga aaataattca acatttaata tatccaatgt
    17581 tgaattgata tataatgaat atgatgagaa taaaaaaatt atatcttcgg atagtaaggc
    17641 tttgttggac atgactttaa tgcctgggaa agttgcttac atagaatgtg ggcataaaac
    17701 ttttgtaaag ggtgtagaag tttatgcata tgaatatgag gcagagggta agattgtgta
    17761 tgttaattta aaagaaaata ctattaatat aagaaataat aatattaagc tagaaaatag
    17821 tagtcagtat gaggtgctat ctacatcaga acttaaaaaa gtaaatgaat caaatgaggg
    17881 aattacgtat caagtaaaag taaaaaattc atcatcaaaa gatttaggaa atattattct
    17941 taagacagca gaagttaatg aaaatggaga atatttaaca gtaaatcgtg tgccatcata
    18001 taagatttta aagccttcag aagagacaga tatagatata ttgtgttcaa caaaggcaaa
    18061 aagtgttgaa atagtgggat atacgtatga tgatataaaa gaaaaagcca atgtggatat
    18121 tgacttaaaa tctcataaag ttaagataga caaataaagg taggggatac ttatgaaggt
    18181 tttaatagtt gaagataata agatactttt agaaagtgta gtagaagaac ttagcaagca
    18241 ttttgaaact gaaaagtgtg aagatggaga agaagcttta tacttagtaa atcaaaatat
    18301 atatgattta gtcattttag acttaatgct tcctaatata aatggatttg atatcctaaa
    18361 gaaaatgaga gttaataata tagatacacc tgtacttata ttgacagcaa aagaaacatt
    18421 agatgacaaa gtagaagcat ttactatagg agctaatgat tatttgacaa aaccttttta
    18481 tatggaagag ttagtagcta gggtatacgc tatattaagg actaatggaa agataaaaga
    18541 aagaaacgga ttagaattta aatctttata tttagataca ctagaaaaaa gagtgtatat
    18601 tgaaaaagaa gaaataaaac ttcaaaacaa acagtttaac ttgcttgagt attttgtatt
    18661 aaataaaggt tcaattttat taaaagagca gatttatgat agaatatggg gaattgattc
    18721 agatgcgact attgaaatag tggaagtata tgtaagtaat ctaagaaaaa aactaagtaa
    18781 atatggatat gataaatata ttaaaactaa acgtaaggta ggatatatat tcgatgataa
    18841 ataagaatgt atttaccagt actaaaaatc atttaataaa aatgtatatt attgtagtag
    18901 gtagtttttt aataatcttt tctatattta tatactcata ttttagggga cttacatata
    18961 gtggaattga tagtgagata aatgatgaac ttgaatatat agtctctcaa tttaaaagaa
    19021 cttcattttt gaacccaata agactgaaag atcctaaaga tatggtgtat gtgtatgaag
    19081 atggaaggat aagttactat actcaaaatg aatattttga tgagttactt ccagatagaa
    19141 gactagataa aaaaaattcg ttttttaaat acacagaaaa tggatatact tttagagaat
    19201 taaatgtaga tgtaggtaga taccaaatac agataattag aaatatagat tctgagatga
    19261 attctttaag acagcttaca tctgttctta taattggaat attaatttct gtaataatta
    19321 cttactttgt ggctgtatat ctcactagaa aagctttaat tccaatagaa acagcatgga
    19381 aaaatcaagc taagtttata caagatgctt ctcatgaatt aagaacacca ataacaatag
    19441 tttcatcaaa attagaaagt atgttaaaat ccccagaaag tacagtaaat gatgaagttg
    19501 aaacaatagc tactgcaatg aaggaaacta gaagacttaa aaaaatgata actgatttat
    19561 tgtctcttac taaagaggac tctattgtta aagttaattt agaagaaata gatttagaaa
    19621 agttattgga agaaatatca gaagactata ttgacattgc tgagtttcag gaaaaaagat
    19681 tcgtgtttaa ttctaaactt aagaataaag ttataataac agataaaaat aaattaagac
    19741 agcttatatt aattttcatt gataatgcct ttaagtatac aaaattgggt gatgagatag
    19801 cattagaatt gaaagaagat atagaggatg aggtaacttt acttataagt gacactggta
    19861 taggcataaa aaaagaagag atacctctta tatttgatag attttttaga agtgaaaatg
    19921 taagaaataa agatttagaa ggttctggaa taggactttc aatagctcgc atgattagtt
    19981 taaacttatc tattgatata aatgtaactt ctgatgtaga tattggaact acatttgaat
    20041 tgtcaatacc caaaaagtta aaataataaa aatataaaaa attgttttta gaaatgaaga
    20101 atgggtatac taattagtat aaaatataaa aagaccttat aaaagtaaat ttatatttat
    20161 aaatttcata gtataattat atagggataa taaagtttaa taggaggatt taaaaatggc
    20221 aaaagttata aatacatctg aatttagaag tagtgttgaa ggtagtaagg gagtagttgt
    20281 agttgatttc tttgcaactt ggtgtggacc ttgtaacatg ttgggacctg tatttgcaga
    20341 attaggtgaa gagatgaagg ataaagctag atttgtaaaa gttgatatag atgagagctt
    20401 agaaatagct caacaattca atgtatctac agtaccaact atgattatat ttaaagatgg
    20461 aaaaccagta gaaactttaa ttggattcat gccaaagaac aaaattgaaa tgcaagtaaa
    20521 atcatattta taaaaaatgg gtgagtatta tgagatatga tatagctata atcggcagtg
    20581 gtccagctgg attgtctgct gctataaatg caaaaataag aaataaaaca attatcatgt
    20641 ttggtaatga taatttaagt aataagcttg ttaaagctcc ttcaatagat aattatttag
    20701 gtttttatga tataagtggt gatgaattaa aagacaagtt taaatcacat atagatagta
    20761 tggatatttc aattgaaaat aaaagaataa ataatattta tgctatggga gaatacttta
    20821 caataatgtc tggaaatgat atgtatgaag ctactactgt aatccttgca actggggtag
    20881 agtatactag accaatcaag ggtgaagaag aatttctagg aagaggtgtg ggctactgtg
    20941 ctacatgtga tgcaccactt tatagaaata aaaaggtagc agttatagga tataatgaag
    21001 aatctaaaga agaagcaaat tttttaagtg aactcacttc aaagacttat tttataccta
    21061 tgtacaaaaa agataatctt atgagaagtt cagataacct agatgattct attgaagtta
    21121 tacatgacag accagtacag atagatggag ataaacttgt aaacaaagta tcttttaaag
    21181 aaaaccacat tgaagttgat ggagtattcg ttataaaaga tagtacagct ccaagtgcat
    21241 tggttcctgg aatagagatt gatggcattc atattaaagt tgacaataat atgaagacta
    21301 gtatagatgg atgctttgct gctggagatt gtgttggaaa accatattct tatataaaag
    21361 cagctggtca agggcaaata gcagctttaa atgctgttta ctatttagat aaattaaaga
    21421 gggcttaata tttatattga ttaacttttt aaagatattt ataaaaaact gtcttgaaat
    21481 aattttatta tttcaagaca gttttttatt tttaagttat taataaaagt attttaaaat
    21541 ctatatgtaa ttacttttat taataaaact caaagttata ttagtaaaaa ttggaattat
    21601 ttataatata ctccaaaatt taaaaataat ggttgaaaaa tctaattaag agtactataa
    21661 tttaattaag taattactta atcaaaacga ggtacttatg gaaaacttgg ttaaaatatt
    21721 taaagcattg agtgatgaaa ctagacttaa catacttata ttagtatcca agagaaatat
    21781 atgtcaaaag gggatttcta aatatctagg gatttcagat tctgctgttt cacaacatat
    21841 aaaaatatta aaagatgttg ggataataac aggatataaa gaaggatact atgttttata
    21901 tcatattaat aaagaatcat ttaatatatg tgtagatttt ataaattcta tgttaagtaa
    21961 ttctagtgaa agctttatag atgtatttga tgtaaataca atacatctag gatgcagtaa
    22021 agaatgtaaa tctataaaaa aatgttgtaa gagaagggag aaataataat gaaagtatgt
    22081 ataccagtag aggagaataa aggattggat agtaaaccat atggacattt tggttctgct
    22141 ccaatttttg ttgtgtgtga tttagaaagt ggagaagtta aatctttaga taatggagat
    22201 ttagatcatg aacatggaaa atgtcaacca ttaaaagcat tgtcagggac agctgtagat
    22261 gcagtagttg ttggaggaat aggacaagga gctataatta aattaaatgg aatgggaata
    22321 aaagtttaca gagcagaagg tgatactata agtgctaatt tagacttact taaaaatgga
    22381 aaattagtag aatttccatc agaccatact tgctcacatg acggatgtgg acatcattaa
    22441 aaaaaaacag ctgatgaaat atatacttca tcagctattt tttcttttaa taaatacgat
    22501 tttattcttt taaaaccaaa atttagattt ttatattttt tgtagtatcc ttaataatat
    22561 ttcaagttta caagtttact acttttagat tttttttgta tgtttttcta tatagtcaat
    22621 atcatttaat atgtcattga gttctttatt aagtgttttt aaatcatcac catctacatt
    22681 gtagtttaaa aatagttcct ctacattatc aatgatagaa ttgacttttc tagtaacttc
    22741 aacaaatgtc ttaaagttac tactattttt agcatttaga aattttttta aatcctttga
    22801 tataaatgat actatttcat attcatcatt aaatagacct ctaccaatag gatatggttc
    22861 aattctctgt aaaaaatatt ggtctttagc attaatatta taagtataag atatttccca
    22921 accgtctcct aaatcaaact tgataaaata taatgtacta cttacttttg atattcttgt
    22981 ggcaccaagc tgtcttaaaa gaacttcaat cgaatcacct tgaacagtat taatattcat
    23041 atatacacat cccctttagt attattatac tatatttttt aaaattttat aattaaataa
    23101 acagtagata taataataga tataatcata agtggaaaac ctattttgaa atactcctta
    23161 aaagagatag gatgaccgtg tttattacct atacctgcta gtacaacatt agcagatgct
    23221 cctattagtg ttccatttcc tccaagacaa gctccaagag atgttgccca ccatagtggc
    23281 attacatcaa taccttcagc ttgcatagtc aaaataagag gaattagtgt tgcaacaaat
    23341 ggaatattat ctaagaaaga agagactata gctgacaacc ataatatcaa caacattgta
    23401 aatacaagat gtccttctgt aagtccaatc aatgcttgag ccaatttgtt tattatccca
    23461 acttctacta atccaccaac tactacaaat aatcccataa agaataaaat tgtagaccat
    23521 tcaatacctg ccataatttc atctacatct tgttttccta ttaaaagcat tatagatgct
    23581 cctgtcagtg ctacaacaga agaatctatg tggattgtac tgtgaaacat aaaaccaaaa
    23641 agtatgaatg ctattaatat aaggcttttt ataagtagag gtttatcttt aacagatttt
    23701 ttttcatcta gttttaatat tgcattttta gctctttcat tcacaacaag ttcttttcca
    23761 taaataaatc taaagcatat tatagttata gcaagtatta ctataacagc aggacctaaa
    23821 tttattacaa aatccataaa actaagattg gcagcactac caatcataat atttggaggg
    23881 tctcctataa gagtagctgt tcctcctata tttgaagcta aaatctgtgt tattaaaaat
    23941 ggaactggat taagtcctaa tatttgtgta ataactatag tcattggtcc aataagtaag
    24001 acggttgtaa cattatctaa tacagctgat aaaatagctg ttataatagc aaagcaaatc
    24061 attatcttcc atgggtcacc cttagctttc tttgcagtcc agatagctat atattcaaat
    24121 aaccccgagt ttttgacaac agctacaaat agcatcatac caactaatac accaatagta
    24181 ttgaaatcta tatggcttaa tccttcatca agtgtaagta tattgaatat tatcattaat
    24241 agtgcaccac caacagctgc tacggatctg tttacctttt ctgtaataat agctgccata
    24301 actattaaaa atatacatat agctattatt tgttgaaatt ccataatata agtacctcca
    24361 tttgtattat tttgtgccta atgctagtac tatatatagt attacttttt tattgttttt
    24421 tcaatggatg tatgaaagta tattatttaa caaagttttt gaaaaattga cagaatttaa
    24481 agaaaatttt tgttatttaa ataaatttta aaattattcc attgat
//
LOCUS       DAEPKC010000056        24123 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.056, whole genome shotgun sequence.
ACCESSION   DAEPKC010000056 DAEPKC010000000
VERSION     DAEPKC010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 24123)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24123)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24123
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.056"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            382..894
                     /locus_tag="KR294_002296"
     CDS             382..894
                     /locus_tag="KR294_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240371.1"
                     /translation="MKVKKFKSGIVMALTVMAIGASLTNVSAMELNKSKEFETKYNEM
                     KMDFQEEYGKEDKFNITLDDEFTKEEVNGAKGIIKTTNKMNNEVVVLNYFDEMKSGIE
                     FELKPKAEKNAILRDEFQQGYGKEDKFKVVLDDEFTKEEVNGAKGIIKTTDKETGEVI
                     VYNYFDELEK"
     gene            complement(1347..2444)
                     /locus_tag="KR294_002297"
     CDS             complement(1347..2444)
                     /locus_tag="KR294_002297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--glyoxylate aminotransferase family
                     protein"
                     /protein_id="HBH0240372.1"
                     /translation="MKKTYLFSPGPVMVTDKVRNSLLHYDICHRGNEFMDLFKDTQQK
                     INKLYNATSNYYSLIVSGSGTSVNECVLSSIFDKEDAVLLVSNGVFGERLEEILSTYN
                     VKTYKPNFEWAEYPDLDILEKYIIENSDIKVIAMVFHETSSGMINPVPELGKLAKKYN
                     KIFFVDAISASAGEYIDVEEFNIDIITGVGGKALGAFPGSAYLCAKESILQNIKENQC
                     KNVYLNLYKHYKVAKSSSQTPNTPNVTLIFALNEALTEFLEDDSKIERYKECSAILRN
                     GMEELGLTFLLPDKYMSNTVTSVFLPKEINVNEFILGLERESGYVVYPGKGKFLDANI
                     FQVANMGEIYPEDCYKFLDILKSKLEIKKVI"
     gene            2737..4263
                     /gene="glpK"
                     /locus_tag="KR294_002298"
     CDS             2737..4263
                     /gene="glpK"
                     /locus_tag="KR294_002298"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HBH0240373.1"
                     /translation="MKYVLAIDQGTTGTRAVLINEKSEFVFSDYMEHTQIYPQSGYVE
                     HDPIEIWNNTKTVSNNVLQQAFENGINESDIKGIGIDNQGETVMLWDKNTGKPLYNAI
                     VWQCRRTYDYVENLKNIPGLENKIIDKTGLIIDPYFSGTKIKWVIDNVKGVKEKIKNG
                     EVLAGTLDSWLIWKMTGGKSFLTDVSTAARTMLFNIRDMDWDRELLDIIGVPRSILAD
                     IMPTSGDFGTTDKEAFCGVSIKITASMVDQPAALFGNGCFEPGMVKNTYGTGCFLYMN
                     IGEELNIAGNGILTTVAWKIGDKVTYAYDGGVYIAGAAIQWLRDGIGVIKNYSETDDM
                     ANSISSTGGVYFVPAFAGIAAPYWDQYARGTMVGITGSTKKEHIVRATLESVALQVKD
                     VVDSMNLASGKKIKMLRVDGGITKNNFTMQFQSDILGIPIEIAENPETTVLGVGYMAG
                     LSCGVWNSIDEIRSEFTISKKYIPNMTTQKREEILLGWNQAVKRAMNWENDTKKVCAN
                     "
     gene            4304..5419
                     /locus_tag="KR294_002299"
     CDS             4304..5419
                     /locus_tag="KR294_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization protein EutH"
                     /protein_id="HBH0240374.1"
                     /translation="MPFDKIILYIMAVGVLLGALDRIIGNKFGLGEQFEEGFNSMGPL
                     ALGMVGIVCLAPVISDVLGPIIIPIFNLCGADPSMFATILANDMGGYPLAMELAHNKE
                     AGMLAGLVVSSMLGCTLVFSIPVGLGLIEYEDRPFFAKGLLIGLITIPFGGIIGGLIA
                     GFNLSMVIINMIPVIILAVILAVGLKFNSTLMINGSLVFGKFISILITIGLGAAAFQE
                     ITGIVLIKGMTPIREGIQVIGSIAIVLLGTFPILHLLVKVLNKPLTIVGGKLGMDATS
                     AAGLVFTLANSIPVYKMMKDMSPKGKVVNTAWLVCATAALGDHLGFTAGVVPEMITPV
                     VIGKLVGGVLAIALAILMTKDLTLEEEQSIKMKKDAV"
     gene            complement(5700..6464)
                     /locus_tag="KR294_002300"
     CDS             complement(5700..6464)
                     /locus_tag="KR294_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBH0240375.1"
                     /translation="MLPQERYEKILSILKSDNIIKINDIVQMFDISIETARRDLAHME
                     SIGLLKRVYGGAIPVIASSVELNYVKRKKINSNDKKQIAIKCSEFINTNDTIFMDTGT
                     TVLEVSKNLKDKKNLTVITNSILVANELMNTNIKVYVLGGYLRETEGSFSGPLTLSAI
                     EQFNVDKAILGAGGITLENGISDYHLEEALVRKKMIERSRKSIVVVEPPKFGINSFAS
                     VAPIEHIDTIITSASIDHNIIIEFSQKGIPLVIADN"
     gene            6723..6813
                     /locus_tag="KR294_002301"
     tRNA            6723..6813
                     /locus_tag="KR294_002301"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:6757..6759,aa:Ser,seq:gct)
     gene            6901..7689
                     /locus_tag="KR294_002302"
     CDS             6901..7689
                     /locus_tag="KR294_002302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor protein"
                     /protein_id="HBH0240376.1"
                     /translation="MTTLIFFIVGIASLVVAFVIDGGHVGALFVFSSALVVFGGTIGA
                     VGASTPFPVFKKSIKIMLLTFKNKKPNNIENIIYFKEIATKARKEGLLSIDKEISEND
                     ELDPFIRKGLELMVDGVDAVTIRNILESQIQITSKRHKEGIAIFDSAGGYAPTLGIIG
                     TVMGLVHILGNLSSNPDALGPQISVAFLATLYGVGSANLIWLPIASKLKAINQQEVSE
                     RLLVIEAILSILEGDNSNLMTEKLKIFLNSKELIELEEIGGRAE"
     gene            7710..8450
                     /locus_tag="KR294_002303"
     CDS             7710..8450
                     /locus_tag="KR294_002303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HBH0240377.1"
                     /translation="MLYDEDEKEENNERWLLTYSDLITLLMIFFVIMYSMSNVDAEKY
                     KQLSQSLNSAFGGSSGVIEGGNSKIEPVVEPGSNDLDTLQNAKFKKIGEEIQKYLNEN
                     GMANSVSLRVQDRGLVISLKDTILFDTGKAIVKDNSRDKIIQIGKMLNEMNSYMRVEG
                     HTDNMSIKNSEFKSNWDLSVMRATNVVQLLIDNAGIAPDKLSAVGYGEFRPIAENSSE
                     EGRSKNRRVDIVLVDSKYDNVENVSKDK"
     gene            8626..9000
                     /locus_tag="KR294_002304"
     CDS             8626..9000
                     /locus_tag="KR294_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240378.1"
                     /translation="MGNKNKNTKYKDKTRERYNKKVENLNKEKLNKINKQSKKVDKID
                     DIINKSSIVLCVLLVVFSLLYLFKLVQLNIIMILLVITVAIQQGLVSFGAFRNKNYVK
                     ALFSIFVIVCFLIAFKYVVNPV"
     gene            9092..10552
                     /locus_tag="KR294_002305"
     CDS             9092..10552
                     /locus_tag="KR294_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBH0240379.1"
                     /translation="MNRCKFAKLIITSMIVLLLTGCSLKKEDNYKLDPENPTSIQIWH
                     YYNGQQKMAFDKLVKEFNDTVGAEKGIIVEAFSQGNVVDLSEKVLDSANKKVGSEDVP
                     NIFAAYSDTAYEMDKLGLLVDMDKYISKEELNEYIDEYVEEGRINSKDEFKLFPIAKS
                     TEILMLNKTDWDKFAKATNSNINDIKTIEGLVETSKKYYEWTDSLTKEPNDGKAFFGR
                     DALANYIIIGSKQLGVEIFSVKDGKVTLNIDEKVMKKLWDNFYVPYINGYFASYGKFR
                     SDDAKTGDILALVGSSSGAAYFPDRVMLNDNESYNIETSVFQAPRFKGEGKYAVQQGA
                     GMAVTKSTKEEEYASVEFLKWFTDKEPNIKFSIASGYLPVKKKTNDLDVIKEVMKKDN
                     LSLSDKVEGSIASSIEQINSCNLYTNKAFDGGTKARQILEYSMLDKAKEDSNKINELV
                     KSGTSKKDAVAQFNNDKNFKTWFESFKAELENAIKK"
     gene            10605..13634
                     /locus_tag="KR294_002306"
     CDS             10605..13634
                     /locus_tag="KR294_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBH0240380.1"
                     /translation="MENNLRKNNSIMKKMIFPLIIVMLIQTSLFCATILWGGTIKKLN
                     DNSFDILNERVINRKNYIQNEMLQRWSNTSETEATINSSVKKVLNEKNALIEDVGNNE
                     EINKDIIKSISNDLIYLLRKNSVTGAFIILSDKNINDKSIDSKGEISRTGLYIRDLDP
                     KFNPNDNSDLLIERGSSDIARSFGISMDSYWEPKFSFKSENEQDGDDFFYKPFRAAID
                     NPNVSSSNLGYWGSKFLLTNAGDRLMTYTVPLIYEDGTVYGVLGIDLSVNYLRELLPY
                     SEINGNKKGNYILGVDRNNDMAFENVISNGYSLKEKFWDGLHSNLEQKESYKNIYKIK
                     NKDNECGNGNIYASVQYLDLYNSNTPFENERWALLGIIEEKSLLSFSKRVEKLVIISI
                     AISLLIGLIGIYIASRLFTKPIVLLANKVRNSNPSKPVNLDKINISEIDELSSAIELL
                     SANVADSSSKLSQIIEMVDMPIGAFELYKNAENVFCTKEFFSVFTTEIKFEEYGYMEK
                     NKFLKKLRGLDKYLQESYETENTYIYKFESKDKKLKWIRMNIFEDELKVLGVVVDVTK
                     EFIEKRKIEYERDFDILTNLLNRRAFHSQIQEKFKNKDELKIAAFIMWDLDNLKYIND
                     TYGHDAGDEYIRCAADILKKFISWNGIVSRLSGDEFYVFIYGYESKDSIRDIINSVKK
                     QMNNTLLKLHDGTEFKIRASAGISWYPDDSTNYDELMRYADFAMYQIKNTIKGEVSEF
                     DINIYNKDSFLLSNREELNKLIDGQLVEYAFQPIVDCKGKVFAYEALMRPKIKTFSSP
                     IDVIRLARSQSKLYQIERITWFKALKSFKKYKEKFGDCKLFLNSIPNNNLSKVDFEEI
                     EDLYGEYLNRVVLEITENDKINEDFIEKKKAYIDHWNIEIALDDFGTGYNGDAVLLYI
                     MPDYVKIDMSIVRGIDKDENRQKILKNLISYSNERNIKVIAEGVETKGEMETLINLGV
                     DYMQGYYISKPSFIPEDISDKIKKELKICHENRNDVV"
     gene            13711..15777
                     /locus_tag="KR294_002307"
     CDS             13711..15777
                     /locus_tag="KR294_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HBH0240381.1"
                     /translation="MVELIITTNIDIRKLNENQLEAVEHIDGPCMILAGPGSGKTRVI
                     TYRIANMVVNKNIAPTRILAISFTKASSIEMKNRALNLSDDIRLNKVTYGTFHSVFFK
                     ILRYFERYNLDSIFDEKSKRMTIKAILKSLNIENADDDENIGQVINEISYVKNELMDK
                     NEFNSEVLTKDEFLKVYNLYEEQKSKVNKIDFDDMLIRTYYLLLNNKSALEMVRNVYK
                     YILIDEFQDINKVQFEVLKLICSPLNNIFAVGDEDQSIYGFRGARPDFLLEFEQYFNN
                     TKKIILDINYRSKSEIVHTANRLIDKNKNRYEKIIKCSQGDGGSVTYISPHDSEEEAL
                     YIAREIIDEIQKDYVEYSDFAVIYRTNIQSRALVDVFMDMRIPFVVKDSVITIYDHWA
                     SQDILAYLRIGINPKSNKDWLRIINKPFRYISKDSINMVKDEKDFITALINKCNLHPK
                     QVKTINDLEIDLSYLNTLNPKNAISYIRTSLDYDRYVLDYCSNRKIKTNGLVEILNEL
                     ESSATNFNTVTEFLEHIDRVKTELTENNKNKQTEGVIFTTMHSAKGLEFRNVYIIGVN
                     EGTIPHEKSYDICKEEKKEEQLEEERRLMYVAITRAEEKLCISSTLNKYGKKVDKSLF
                     INDIKSPTKKEIDSIGVGDKVYHKKFHEGEIIKKDGIMFTIKFKDRERILDLKTCLLK
                     NIIYTI"
     misc_binding    16160..16370
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            16596..17411
                     /locus_tag="KR294_002308"
     CDS             16596..17411
                     /locus_tag="KR294_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HBH0240382.1"
                     /translation="MKVFKKLLSLGLVLGLTLSLVGCSGGGEKTKLEQIKDNGKLVVG
                     TSAEFPPFEFHKVVDGKDSIKGFDIMLAEEFAKELGVKVEIKDMSFDGLIGALNADQV
                     DIVLAGMSPTPEREKSVDFSELYYLSRNAVIVKDADIDKVKTEDDLKKLRVGVQAGSI
                     QEEYVVNTLKMTTTKSLKAIPDLITELKNGNIDAVVTNEAVSLINVKKYDGIKMANTE
                     VGKDVTEGMAAAIKKSDNNKDFIELLNKKIKELQDGKKIEEFLNEASTEAASN"
     gene            17439..18116
                     /locus_tag="KR294_002309"
     CDS             17439..18116
                     /locus_tag="KR294_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBH0240383.1"
                     /translation="MSLDFSFLSRFGTSFLEGTGVTVSISLVALCFGFIIGIIICMAK
                     ISKSKVLRAISSIYIEVLRGTPLLVQIYIVWFGLPQLGIRFPMLFGIPSEFIASAFAL
                     SVNSGAYVAEILRSGIQSVDNGQMEASRSLGLNYWSTMRYIIIPQAIKNILPSLANEF
                     ITLVKESSIISVIGVVEIMRTADIVKNAAFRALEPLIVAAAIYFVITFTLSRLVGLLE
                     KKLSVSN"
     gene            18175..18897
                     /locus_tag="KR294_002310"
     CDS             18175..18897
                     /locus_tag="KR294_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004398740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBH0240384.1"
                     /translation="MITIKNLSKSFGDLNVLKNIDLEIAKGEIMVIVGPSGSGKSTLL
                     RCMNLLEIPTGGEIIFEGKNLVDKKTNIDEVRQNIGMVFQNFNLFPHKTILDNITLAP
                     IKLKKMTKEEAEKKAEILLSRVGLLDKKDSYPSQLSGGQKQRIAIARALAMEPDMMLF
                     DEPTSALDPEMVNEVLDVIKELAKEGMTMAIVTHEMGFAKEVADRVIFIDGGSILEDN
                     TPEEVFGNPKHERTKAFLAKVL"
     gene            19545..20696
                     /locus_tag="KR294_002311"
     CDS             19545..20696
                     /locus_tag="KR294_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HBH0240385.1"
                     /translation="MEIYLDNSATTKPYQEVIDKMVYALNTEYGNPSSVHRKGVEVEK
                     AIKEVRQDIAKSLGAKEKEIYFTSGGTECNNTIIRGITSLNKKRKNHIISTNIEHPSV
                     LNTLKDLEEDGFEVTYLEVGKDGKINIEDLKNAIKSTTCLVSMMHVNNEIGTIQPIGE
                     VGKYLKGLKEKIYFHVDAIQSYGKINFRLSKYNIDFMSVSAHKFHGPKGIGFMYIKEN
                     NRLKPMLTGGGQEIGIRSGTENVPGIYGLGEAVRILNKDLDVVISKVNNLKNILKNEI
                     IDNIEDIKINSPEDGVCHILNVSFRGTKGEVLLHYLEQKGIYVSTGSACSSKKKGSYV
                     LNAIGLTNEEINGTIRFSLSDMNTEEEMLEAVKVLKESICDLRSIMKRK"
     gene            20742..21917
                     /gene="thiI"
                     /locus_tag="KR294_002312"
     CDS             20742..21917
                     /gene="thiI"
                     /locus_tag="KR294_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HBH0240386.1"
                     /translation="MVYNILIVKYGEIGVKGKNRYIFENRLIRNIRNMLKPIGRFNVY
                     KEYGRIYVDLEDYDYEEVIEEVRKVFGIVGVCPGVRAKKDYDTLKEIALKMLEEKIEA
                     GYKTFKVESRRGDKSFGLTSQEMSMDIGGYLLSKVGDRINVDVRNPEVKIKCEYREFH
                     TMVYSDTIPGYGGLPLGTNGRAMSLLSGGIDSPVATWMVAKRGMEVEAVHFHSYPFTS
                     ERSQEKVKDLAKILAKYCGRVRLHKVNILEIQKAIGENCNEEEATILSRRFMMRIAQR
                     LSEKRHCDALITGESIGQVASQTIQGLTCTNAVVDLPVFRPLIAMDKSDIVDIAKKIG
                     TFETSILPEEDCCSVFSPRKPVTKPRLEKIEKSETALDIEKLVQDAIDKIEVEDIEF"
     gene            22073..22876
                     /locus_tag="KR294_002313"
     CDS             22073..22876
                     /locus_tag="KR294_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HBH0240387.1"
                     /translation="MNKKGFTLIELLVVISIIGILVIVAVPALFRNIEKSKAVTCLSN
                     RENIKTQIVIAMAEESSKGKNEVMKEVLENKDGKYFETEPKCKSGGIYSATFDDGYDG
                     ITGIESIAKVYVTCTKHPDGVEMARDIHQSMKDLIASFSQDPSIIPGASKGNDDFRKY
                     LLDNKYKNGWPTIPDEFKAKYGLSKDTLYIQPYAYSPTKSDATVVVFANNKTGGNWYT
                     SLVYDYDEGRWYKGKNGISVAGRSWDVDTDSVKSVKTEIHSKEGWGPLN"
     gene            23119..23760
                     /locus_tag="KR294_002314"
     CDS             23119..23760
                     /locus_tag="KR294_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase"
                     /protein_id="HBH0240388.1"
                     /translation="MNNNFQDNQTINLIQSRRSIRKFTTEQISDEQVNTLLHCAFAAP
                     SGCNKQPWHITVVQDQKLLKEISDDTLSRIHEVSNVEINKNFKLFYGAPTVLFISYDE
                     SSSWAPYDIGILTGNITTAAQALGLGSCIIGMVRGLFTPVEQGDIEGLVSVLDKEDVK
                     ESESIKMKFDTNKKYRELLDIPEGYSVPFGIAVGIPDGNLPNAREVVYKVSRV"
BASE COUNT         9582 a         2470 c         4339 g         7732 t
ORIGIN      
        1 gaatattcag taaaatgatt ttgatatact ctctatattt tgtatgttaa aagtaaataa
       61 attattgtta aagaaggtaa agacttttaa atttcttatc ataggatttt aagtaaataa
      121 gaaggattgg agtaattaaa aatttttatt ttgcaaaaat aagtatttat ttatatggat
      181 aaatttgatt ttaaatctat aaatatagat aaaatctaat tatttaactt caactattcc
      241 tcaaaaaagc aacttttaag gaatagttga agcaaaaagt ttggttacat aatagtaatt
      301 ttagttacaa gaatgaaact gtaaaactta ggattttctt tatataattt cattgagaac
      361 atttaattta ggaggtaaga tatgaaagta aaaaaattta aaagtggtat agtaatggca
      421 ttaacagtaa tggcaattgg agcatcattg acaaatgtat cagctatgga attaaacaag
      481 agtaaagagt ttgaaactaa atacaatgaa atgaagatgg attttcaaga ggaatatgga
      541 aaagaagaca aatttaatat aacattggat gatgaattta caaaagaaga agtaaatgga
      601 gctaaaggga ttataaagac aactaataaa atgaataatg aggttgtagt attaaattat
      661 tttgatgaaa tgaaatctgg aattgaattt gagttgaagc caaaagcaga aaaaaatgca
      721 attttgagag atgaatttca acaaggttat ggaaaggaag ataaattcaa agttgtgtta
      781 gatgatgaat ttacaaaaga agaggtaaat ggagctaagg gcattataaa gactacagat
      841 aaagagacag gtgaggttat cgtatataat tactttgatg agcttgaaaa ataatgctta
      901 aagattactt tgattgaatg aaaaggtaat tgtgttgaga atataaaatg actgaataaa
      961 aacagttgta tcaaaacaaa caataataga atgtaagaat gattgtgttg aaaatattaa
     1021 atgactgaat aaaaaacgat tgtgtcaaaa ataaaaaata attaagtgta agaatgattg
     1081 tatcaagaat ataaaatgac tgaataaaaa acgattgcgt caaaaataaa aaacaattaa
     1141 atgtaagaat aattatgtca aaaatataaa ataaattaaa agaaaaagat tatattgaag
     1201 gaaaaagatt tgaaataggg gtgaacttta catattatag ttcaccctta tacaaaaata
     1261 taaaatataa tttattatag gaaaatttaa aaaaatcagt ctatttaatt tatactgata
     1321 tattgtagga ttttacaaac aaactgttat ataacttttt ttatctccaa ttttgatttt
     1381 aagatatcta agaatttata acaatcttct ggatatattt ctcccatatt tgctacttgg
     1441 aatatattag catctaggaa tttacctttt cctggataga caacatagcc actttccctt
     1501 tctagcccta atataaactc atttacattg atttctttag gtagaaatac agatgttact
     1561 gtattagaca tatacttatc tggaagtaaa aatgttagac ccaattcttc cataccattc
     1621 cttaaaatag cagaacattc tttgtatctt tctattttac tgtcatcttc caaaaactca
     1681 gttaaagctt cattaagggc aaatattaaa gtaacattag gtgtatttgg tgtttgagaa
     1741 gatgatttag caactttata gtgtttataa agattaagat acacattctt acattgattt
     1801 tctttaatat tttgtaaaat actctcttta gcacaaaggt atgcagaacc tggaaatgct
     1861 ccaagagctt tgccaccaac acctgttatt atatctatat taaactcttc cacatcaata
     1921 tattcacctg ctgaggcact tattgcatct acaaaaaata ttttgttata cttcttagca
     1981 agttttccta gttcagggac tggatttatc attcctgaac tagtttcatg gaacaccata
     2041 gcaattactt ttatatcaga attttcaatt atgtattttt ctaaaatgtc taggtccggg
     2101 tattctgccc attcaaaatt aggtttatat gtttttacat tataagtaga taatatttct
     2161 tctagccttt ctccaaaaac accattacta actagcagaa ctgcatcttc tttgtcaaag
     2221 atagaagata gtacacattc atttacagat gttccagagc cagatacaat taatgagtag
     2281 taattagaag ttgcattata tagtttattg attttttgtt gtgtatcttt gaataaatcc
     2341 ataaactcat ttcctctatg gcatatatca tagtgaagaa gtgaatttct gactttatct
     2401 gtaaccatta ctggtccagg actgaataga tatgtttttt tcattgtaaa gcctccttaa
     2461 aaagttaaat ttaaattttt gaatgactga ttatgtgtaa atattaaaat attatgtgtt
     2521 attttaacta gattatagaa taaaataata aatattgcaa taatatttca ataaaaatac
     2581 ttttttaatc actataatta aaaataacaa aaaatattgt aatgaatatt gcataaatcc
     2641 acatgatgat ataaaatata aataacttga atagattata tattcaaaaa ataaaaaaga
     2701 atttattaat tctgaaaata aagggggaca tttaaagtga aatatgtatt agcaattgac
     2761 caaggaacaa caggaacaag agcagtattg ataaacgaaa aatcagagtt tgtttttagc
     2821 gattatatgg aacatactca aatatatcca caatctggat atgttgaaca tgaccctata
     2881 gaaatttgga ataatacaaa aactgtgagt aataatgtat tacaacaggc ttttgaaaat
     2941 ggaatcaatg aaagtgatat aaaaggaatt ggtatagata atcaaggtga aacagtaatg
     3001 ttatgggata aaaatacagg taaaccactt tacaatgcta ttgtgtggca gtgcaggaga
     3061 acttatgatt atgtggaaaa tttaaagaat ataccaggtt tagaaaataa gataatagat
     3121 aagactgggt taattataga cccatatttc tcaggtacaa aaattaaatg ggtaatagat
     3181 aatgtaaaag gtgtaaaaga aaaaattaaa aatggagaag tacttgcagg aacattagat
     3241 agttggttaa tatggaaaat gacaggagga aaatcttttt taactgatgt atctacagca
     3301 gcaagaacaa tgctttttaa tataagagat atggattggg atagagagtt gcttgacatt
     3361 ataggagtac ctagaagtat tttagcagat ataatgccta cgagtggtga ttttggaact
     3421 acagataagg aggcattttg tggggtttct ataaaaatta ctgcttcaat ggtagaccaa
     3481 ccagcagctt tatttggcaa tggatgtttt gaaccaggaa tggttaaaaa tacttatggt
     3541 acaggatgtt tcctatatat gaatataggt gaggaactaa atatagcagg taatggtatt
     3601 ttgacaactg ttgcttggaa aataggagat aaagttacat atgcttatga tggtggagtg
     3661 tatatagcag gtgctgcaat acaatggctt agagatggca ttggagttat aaaaaattat
     3721 tcagaaactg atgacatggc aaattccata tcaagtactg gaggtgtata ttttgtacca
     3781 gcatttgcag gtatagcagc accttattgg gaccaatatg ctagaggtac aatggttgga
     3841 ataacaggaa gtactaaaaa agagcatata gtaagagcga ctcttgagtc tgttgcactt
     3901 caagtcaaag atgttgttga ttctatgaac ttagcctcag ggaaaaaaat aaaaatgttg
     3961 agagtagatg gtggaattac taaaaataac tttacaatgc aatttcaatc cgacatatta
     4021 ggtataccaa ttgaaattgc agaaaatcct gagacgacag tacttggagt aggatatatg
     4081 gcaggtcttt cttgtggtgt ctggaacagt attgatgaaa ttagaagtga atttacaata
     4141 agcaaaaaat atattccaaa tatgactact caaaaaagag aagaaatatt acttggatgg
     4201 aaccaagcag taaaaagagc tatgaattgg gaaaacgata ccaaaaaggt gtgtgctaat
     4261 taagttacaa tagagtattt tacatgtata ggaggaatta aaaatgccct ttgataaaat
     4321 tatattatac ataatggctg tgggagtgct tttaggagcg ttagatagaa taattggaaa
     4381 taaatttgga cttggcgagc agtttgaaga agggtttaat tcaatgggtc cattggcttt
     4441 aggaatggtt ggtatagttt gtttagctcc agtaatttca gatgtactag gtcctataat
     4501 aataccaatc ttcaatctct gtggagctga cccatctatg tttgcaacta ttttagcgaa
     4561 tgatatggga gggtatccat tggctatgga acttgcacac aataaagagg caggaatgct
     4621 tgcaggattg gttgtgtcat ccatgcttgg atgtacatta gtattttcaa ttccagtagg
     4681 actaggtctt atagaatatg aagacagacc attctttgca aaagggttac tgataggctt
     4741 gataacaata ccttttggag gtattatagg aggattaata gcaggattta acttatcaat
     4801 ggtaattata aatatgatac cagtgataat attggcagta atattggcag taggtttaaa
     4861 atttaattct acgcttatga taaatgggtc attagttttt ggaaaattta tatctatatt
     4921 gataacgata ggtttgggag cagcagcatt tcaagaaata acaggtatag tacttataaa
     4981 aggcatgaca cctataagag aaggtattca agtaattgga agtattgcaa tcgtgttatt
     5041 aggtactttt ccaatattac atttattagt taaagttctt aataaaccac ttacaatagt
     5101 gggtggaaaa ttaggtatgg atgccactag tgcagcagga ttagttttta ctttagccaa
     5161 tagtattcca gtatataaaa tgatgaaaga tatgagtcca aaggggaaag tagtaaatac
     5221 tgcttggctg gtttgtgcta cagcagcttt gggggaccat ttaggattta cagcaggagt
     5281 agttccagag atgattacac ctgttgtaat tggaaaattg gttggaggag tattggcaat
     5341 tgcacttgct atacttatga caaaagattt aaccttggaa gaagaacaaa gtattaaaat
     5401 gaagaaagat gcagtgtaga ataaacaata cttaagtcaa atttaaatta ttttaaagta
     5461 ggagtttaaa taactaaaaa taaattaaaa agacagacaa ttaaaaaata atcgaataac
     5521 taaaacttat aaattaaata aaatggcaat caaataacta aaaatgataa gctaactgaa
     5581 agtagttaca taattaaaat ataaagtata gtttagacat aaatggagct aaataaataa
     5641 ttatttggct ccttaatttt aatttattac atcaaggaac taaaaatcaa tcatataagc
     5701 taattatcag ctatgactaa aggtattcct ttttgagaaa actctattat tatattatgg
     5761 tctatactag cagaggtaat aatagtatct atatgttcta taggagctac tgatgcaaat
     5821 gaatttatac caaacttagg aggttcgaca actactatag attttctaga cctttcaatc
     5881 attttttttc taacaagtgc ttcttctaag tgatagtcag agattccatt ttcaagagtg
     5941 atacctccag cgcctaaaat agctttatca acattaaatt gttcaatagc tgacagtgta
     6001 agcggaccag aaaaagaacc ttcagtttct ctaagatagc ccccaagcac atatactttt
     6061 atattagtat tcataagctc gtttgcaact aaaattgagt tggttattac agttagattc
     6121 tttttatctt tcaaattttt tgaaacttca agtacagtag ttccagtatc cataaaaata
     6181 gtatcatttg tatttataaa ctcactacat ttaatagcaa tctgtttttt atcgtttgag
     6241 tttatttttt ttcttttaac atagttaagt tctacgctac ttgctataac tggtatagca
     6301 ccaccataaa ctctttttaa aagaccgata ctctccatat gggctaaatc tcttcgtgca
     6361 gtttctattg atatatcaaa catttgaact atgtcattta ttttaattat attatctgat
     6421 ttgagaatac ttaaaatctt ctcatatctt tcctgtggta acataaaata tcctccttgg
     6481 actagtatta ttttagtttt ggcataactt acaattaagt cagagtttag gtatatttgt
     6541 taatgtatgt atatttatca aataatatta taagtgttat gcaagataat tttaccatat
     6601 ttaaaactta catttaagca aaaaagtaaa aatagatgtt taataattca aaataactca
     6661 aattttataa aacaattgac taaaatatga ttttattata taatttacta gtatagagat
     6721 atggagaagt actcaagtgg ctcaagagga tcccctgcta agggattagg ctgggtaacc
     6781 ggtgcgaggg ttcgaatccc tccttctccg ccaattatta aaggctattt ttattaaaga
     6841 tagtcttttt ataatgtcat aaatgattag atatgtataa ctaaagaaag gagggaatag
     6901 atgacaactt taattttttt catagtgggg atagcatctt tggtagttgc ttttgttatt
     6961 gatgggggac atgttggagc attatttgta ttttcatcag cacttgttgt gtttggtgga
     7021 actataggag ctgttggagc ttcgactcca ttccctgtgt ttaaaaagtc tataaagata
     7081 atgttattaa cttttaaaaa taaaaagcct aataacatag aaaatataat ctatttcaaa
     7141 gaaattgcaa caaaggctag gaaagagggg cttcttagta ttgacaaaga aataagtgag
     7201 aatgatgaat tagacccttt tattagaaaa gggcttgaac ttatggtaga tggagtggat
     7261 gcagttacta taagaaatat attggaatca cagatacaga taacatcaaa acgacataaa
     7321 gaaggaatag caatttttga ttcagcaggt ggatatgcac ctacactggg gataataggt
     7381 acagttatgg gattagtaca tattttaggt aatctttcaa gtaatccaga tgcattagga
     7441 cctcaaattt ctgttgcatt tttggctact ttgtatggtg ttggttctgc caatttaata
     7501 tggttaccaa tagcatcaaa acttaaggct ataaatcaac aagaagtaag tgaaagactt
     7561 ttggtgatag aagcaatatt atccatactt gagggtgata attctaattt aatgacagaa
     7621 aaattaaaaa tatttttaaa ttcaaaagaa ctaattgaac ttgaagaaat tggtggtaga
     7681 gctgaataat ataaaaggat ggaatgttta tgttgtatga tgaagatgaa aaagaagaaa
     7741 acaatgagcg atggctttta acttattcag acctcataac attacttatg attttctttg
     7801 taataatgta ttctatgagt aatgttgatg cggagaaata taaacaatta tctcaatctc
     7861 taaattctgc ttttggtggt tcttctggag ttattgaagg tggtaatagc aagatagaac
     7921 cagtagttga accaggaagt aatgatttag atactttaca aaatgctaag tttaaaaaaa
     7981 ttggtgaaga aattcagaag tatttaaacg aaaatggtat ggctaattca gtatcattaa
     8041 gagttcaaga tagaggatta gtaataagcc ttaaagatac aatactattt gatacaggga
     8101 aagctattgt gaaggataat tctagagata agattattca aataggtaag atgttaaatg
     8161 aaatgaatag ttacatgaga gtagaaggcc atacagacaa tatgtctata aaaaattcag
     8221 agtttaagtc aaattgggat ttatcagtta tgagagcaac caatgttgtt caacttctta
     8281 ttgacaatgc aggtatagca ccagataaat tatctgctgt aggatatggt gagtttagac
     8341 caatagcaga aaattcatct gaagaaggta ggtcaaaaaa tagaagagtt gatatagttt
     8401 tagttgatag taaatatgat aatgtagaaa atgtttcaaa ggataaatag ttaaattagc
     8461 tgtctcaata cagaattaat tctaaaggag atggcttttt tatgcgaaaa tcaaaaatag
     8521 atacatagta agttaccttt ttgtaggaat atatggtatc ttaaatatat aatatttaaa
     8581 taatgtataa gctcaattaa aaaatttata gaggatggaa aataaatggg aaataaaaat
     8641 aaaaatacta aatataaaga taaaacaaga gaaaggtata ataaaaaagt tgagaattta
     8701 aataaagaaa aattaaataa aattaataag caatctaaga aagtagataa gattgatgat
     8761 attattaata aatctagtat tgtattatgt gtacttctag tagtgttttc attgctttac
     8821 ttatttaaac tggttcaact taatataata atgatacttt tagtaattac agtagctatt
     8881 caacaaggat tggtgtcatt tggtgcattt agaaataaaa attatgtaaa agctttattt
     8941 tctatatttg taatagtatg tttcttaatt gcttttaaat atgttgtaaa tcctgtttaa
     9001 atatatcaat aaacgttcta taattaatat aaatagtgaa gttacagttt taatgctatt
     9061 ataaatttta taatttgaag gagtagattt tatgaatagg tgtaagtttg caaaattaat
     9121 tatcacatca atgattgttt tattacttac aggatgtagt ttaaagaagg aagataatta
     9181 taagttagac ccagaaaatc cgacatcaat acaaatttgg cattattata atggacagca
     9241 gaaaatggct tttgataagc ttgttaagga atttaatgac actgtaggtg ctgaaaaagg
     9301 aattattgtt gaagcattca gtcaaggtaa tgtagttgat ttatcagaga aagttttaga
     9361 ttctgcaaat aaaaaagttg gttctgaaga tgtaccaaat atatttgcag catactcaga
     9421 tactgcatat gaaatggata aattagggtt actagtagat atggataagt acataagtaa
     9481 agaagaatta aatgaataca tagacgaata tgtagaagaa ggcagaataa attctaagga
     9541 tgagtttaaa cttttcccaa ttgcaaaatc aactgaaatt ttgatgttaa ataaaactga
     9601 ttgggataaa tttgcaaaag ctacaaattc aaatataaat gatataaaaa caattgaagg
     9661 attagtagag acatcaaaaa aatattatga atggacagat agtttaacga aagagcctaa
     9721 tgatggtaaa gcattttttg gaagagatgc tttagcaaat tatattatta taggaagtaa
     9781 acaactagga gtagaaattt tttctgttaa agatggtaaa gttacactaa atattgatga
     9841 aaaagttatg aaaaaactat gggataattt ctatgtacca tatataaatg gatattttgc
     9901 ttcttatggt aagtttcgtt ctgatgatgc aaaaacaggt gatatattag ctcttgtagg
     9961 ttctagttca ggagcagcat actttccaga tagagtaatg ctaaatgata atgagagtta
    10021 taatattgaa acatctgttt ttcaagcacc acgttttaaa ggagaaggaa aatatgctgt
    10081 acaacaaggt gcaggaatgg ctgtaacaaa atctactaaa gaagaagaat atgcatcagt
    10141 agaattttta aaatggttta cagataaaga acctaatata aaattctcta ttgcttctgg
    10201 atacttacca gtaaagaaaa aaacgaatga tttggatgtt ataaaagaag ttatgaagaa
    10261 agataatttg agtttatctg ataaagttga aggttcaata gcctcatcta ttgaacagat
    10321 taacagttgt aatttatata ctaataaagc atttgatggt ggaactaaag ctagacaaat
    10381 acttgaatat tcaatgcttg ataaagctaa agaagattca aataaaataa atgaattagt
    10441 aaaaagtgga acttctaaga aggatgcagt agcacaattt aataatgata aaaattttaa
    10501 aacttggttt gaaagtttta aggctgagct tgaaaatgct ataaaaaaat agatgaattg
    10561 gcagttagtg tgttgacgag cacaaaggta taggtggaat gggtatggaa aacaatctaa
    10621 gaaaaaacaa ttcaataatg aaaaagatga tatttcccct aattattgtt atgctaattc
    10681 aaacaagttt attttgtgcc acaattttat ggggaggaac tattaagaaa ttaaatgata
    10741 attcgtttga catcttaaat gaaagagtaa ttaatcgtaa aaattatata caaaatgaaa
    10801 tgttacaaag atggtcaaat acaagtgaaa cggaagctac aattaattcc tctgtaaaaa
    10861 aagtattaaa tgaaaaaaat gccttaattg aggatgtagg caacaatgaa gaaattaaca
    10921 aagatattat aaaaagcata tcaaatgatt taatatatct tttgagaaaa aattctgtta
    10981 caggagcttt tataatccta agtgacaaaa atattaacga taagtcaata gatagtaaag
    11041 gtgaaataag taggacagga ttgtatataa gggatttaga ccctaagttt aatccaaatg
    11101 ataattctga tttgttaatt gagagaggtt catcagatat agcaagaagt tttggaatat
    11161 ctatggacag ttattgggaa cctaagtttt catttaaaag tgaaaatgag caagatggag
    11221 atgatttttt ttataaacca tttagagctg caattgataa tccaaatgta tcaagttcta
    11281 atttaggata ctggggaagt aagtttttat tgacaaatgc aggtgatagg cttatgacat
    11341 atacagttcc ccttatttat gaagatggaa ctgtatatgg agtacttgga atagatttaa
    11401 gtgtaaatta tttaagagaa ttacttccat actcagagat aaatggaaat aaaaagggta
    11461 attatatttt aggtgtagat agaaataatg atatggcctt tgaaaatgta atttcaaatg
    11521 gatactcatt aaaagaaaaa ttttgggatg gtttacattc taatttagag cagaaggaat
    11581 cgtataaaaa tatatataag attaaaaata aagataatga atgtggtaat ggcaacattt
    11641 atgctagtgt acaatacttg gatttatata actccaatac tccatttgaa aatgaacgtt
    11701 gggctctttt gggtattatt gaagaaaaaa gtcttttgtc attttcaaaa agggtagaga
    11761 aattagttat aatatctata gcaatttctt tattaatagg tctaataggt atttacattg
    11821 catcaagatt atttacaaaa ccaattgttc ttttagccaa caaagttaga aacagtaatc
    11881 catcaaaacc agtaaatctt gataagataa atatatctga aatagatgaa ttatcttcag
    11941 ctatagagtt gctcagtgca aatgttgcag attcttcgtc aaaattatca cagattattg
    12001 aaatggtaga tatgccaatt ggggcttttg agttatacaa aaacgcagag aatgtttttt
    12061 gtacaaaaga attttttagc gtgtttacta ctgaaatcaa atttgaagaa tatggatata
    12121 tggaaaaaaa taagttcctg aaaaaattaa ggggactaga taaatatttg caagaaagtt
    12181 atgaaacaga aaatacatat atatataagt ttgaatctaa agataaaaaa cttaagtgga
    12241 taagaatgaa tatctttgaa gatgagctaa aggttcttgg tgttgttgtt gatgtcacaa
    12301 aagaatttat tgagaaaagg aagatagaat atgaaagaga ttttgatatt ttaacgaatc
    12361 ttttaaatag gagagctttt cattcacaga tacaagaaaa atttaagaat aaagatgaac
    12421 ttaagatagc agcatttatt atgtgggatt tagataatct aaaatatatt aatgatacat
    12481 atggacatga tgctggtgat gaatatatta ggtgtgctgc agacatactt aagaagttta
    12541 tatcatggaa tggtatagta tctagacttt caggtgatga gttttatgta tttatatatg
    12601 gatatgaaag caaagatagt ataagagata ttattaattc tgttaagaaa cagatgaata
    12661 ataccttatt aaaacttcat gatggaacag aatttaaaat aagggcatca gcaggaattt
    12721 cctggtaccc tgatgactca accaactatg atgaattaat gagatacgca gattttgcta
    12781 tgtatcaaat taaaaataca atcaagggtg aagttagtga atttgatatt aatatatata
    12841 ataaggattc attcttattg agtaatagag aagaattaaa caagttaatt gatggtcaat
    12901 tagttgagta tgcatttcag cctattgtag attgtaaagg taaagtattt gcatatgaag
    12961 cacttatgag acctaaaata aaaactttta gttcaccaat agatgtcatt agattagctc
    13021 gttcacagtc taaattatat caaattgagc gtattacatg gtttaaagca cttaaatcat
    13081 ttaaaaaata caaagaaaaa tttggcgatt gcaaattgtt cttaaattct attcctaata
    13141 ataatttgtc aaaagtagat tttgaggaaa ttgaagattt atatggtgaa tatttaaata
    13201 gagtagtact agaaataaca gagaatgata agattaatga agattttatt gaaaaaaaga
    13261 aagcatatat agaccattgg aatatagaaa ttgctttaga tgattttggg acaggttaca
    13321 acggagatgc tgtactatta tatataatgc cagactatgt aaagattgat atgtctattg
    13381 taagaggtat tgataaagat gaaaacagac agaaaatatt aaaaaatctt atctcatatt
    13441 ctaacgaaag aaatattaaa gtgatagcag aaggtgtaga aacaaaaggt gaaatggaaa
    13501 cactaattaa tcttggagta gattatatgc aaggctacta tattagtaaa ccatcattta
    13561 tacctgaaga tataagcgac aaaattaaaa aagaactcaa gatatgtcat gaaaatagga
    13621 atgatgtggt ttaatagagg aaaaattaaa tttattttta tgaactttta gtttataatt
    13681 aaaaagaaaa taatataatt ataaatcaag gtggtggagc taataatcac aacaaatata
    13741 gatataagaa agttaaatga aaatcaatta gaagcagttg agcatataga tgggccttgc
    13801 atgatacttg cagggcctgg ttcaggtaag accagagtaa ttacatatag aatagccaat
    13861 atggttgtaa acaaaaacat agcaccaaca agaatcttgg caataagttt taccaaggca
    13921 tcttcaatag aaatgaaaaa tagagctttg aatttaagtg atgacataag acttaataag
    13981 gtaacctatg gtacttttca ctctgtattt tttaaaattc taagatactt tgaaagatac
    14041 aacttagaca gtatatttga tgaaaagtca aagcgaatga caatcaaggc aatcctaaaa
    14101 agtttaaata tagagaatgc tgatgatgat gagaatatag gacaagttat aaatgaaatt
    14161 tcctatgtaa aaaatgaact tatggataaa aatgaattta attcagaagt attaacaaaa
    14221 gatgagtttt taaaagtata caacttatac gaagaacaaa aatctaaagt taataaaata
    14281 gattttgatg atatgcttat aagaacttat tatttacttt tgaacaataa gtctgcacta
    14341 gaaatggtta gaaatgtgta taaatatata ttgatagatg aatttcaaga tataaataaa
    14401 gtacagtttg aagttttaaa gttaatttgt agcccattaa acaatatatt tgcagttgga
    14461 gatgaagacc aaagtatata tggatttaga ggtgctagac cagatttttt gcttgaattt
    14521 gaacaatact ttaataatac taaaaaaata atattagata taaattacag gtctaaaagt
    14581 gagatagtgc atactgcaaa tagacttatc gacaaaaata aaaatagata tgaaaaaatc
    14641 attaagtgta gtcaggggga tggaggaagt gttacctata tttctccaca tgattcagag
    14701 gaagaagcct tatatattgc cagggaaata attgacgaaa tacaaaaaga ttatgtagag
    14761 tattcagatt ttgcagtaat ttatagaact aatatacagt caagagcatt agtagatgta
    14821 tttatggata tgaggattcc atttgtagta aaagactcag taattacaat atatgaccat
    14881 tgggcaagtc aagatatact agcctattta agaataggta ttaatccaaa atcaaataaa
    14941 gattggttga gaattataaa caagcctttt agatatatat ccaaagacag tataaatatg
    15001 gttaaggatg aaaaagactt tataacagca ttaataaata agtgtaatct tcatcctaaa
    15061 caagttaaaa caataaatga tttggaaata gatttaagtt atttaaatac tttaaatcct
    15121 aaaaatgcaa tatcttatat tagaactagt cttgattatg atagatatgt tttagattat
    15181 tgtagcaaca gaaagataaa gactaatgga cttgtagaga tattaaatga acttgagagt
    15241 tcagcaacta attttaatac tgttacagag tttttagagc atattgatag agtaaagact
    15301 gagttaacgg aaaataacaa gaataagcag actgagggtg tcatatttac aactatgcat
    15361 agtgcaaaag gattagaatt tagaaatgtt tatattatag gtgtaaatga aggaacaata
    15421 cctcatgaaa aatcatatga tatttgtaag gaagagaaaa aagaagaaca attagaagaa
    15481 gaaagaagac ttatgtatgt tgctattaca agagctgaag aaaagttatg tataagctct
    15541 actttaaata agtatggtaa gaaagttgat aaatcattat ttattaatga tataaaatct
    15601 ccaacgaaaa aagaaattga cagtattggt gtaggggata aggtatacca taaaaaattt
    15661 catgaaggag aaataattaa aaaagatgga attatgttta caataaagtt taaagataga
    15721 gagcgaatct tggatttgaa aacttgttta ttgaagaata taatttatac tatttaattt
    15781 agaatctaaa tttagataga aatataatgt attatttatt atgtgcaaga caaatagata
    15841 tgtgtaaaat gtattattta acttattaga aaaagaaata agggtttaat atattattta
    15901 tagttgttta gaaaaagcaa caatgtggaa aatattattt agtattatta aagaaaagca
    15961 acaatgtgaa agatattatt tagtattatt taagaaatag ctaaaaatat gaaatatact
    16021 atttataatt acacaaataa tatcaataaa tataaacagt agtatttaga taatttacaa
    16081 gtaaaaatta ttaaaaaaat aaaaaactta ttgacaaaaa tattataagg aagtacaatt
    16141 gtattaacaa tttaaggaaa caaatccaat gatagagaaa gtagcatata tggatttaca
    16201 gcgagttagg ggttggtgta agcctaacaa tgaagtctat gtgaagagag ctctggagga
    16261 gattatcaga aactttagta tgataattgg tttacccgcc ttaagggatt gagaggataa
    16321 gtacttactt atcaaaaaga gtggtaacgc ggatataatt cgtctcttag ctgtaaagct
    16381 aagggacttt tttgatttta aaataaaaat atccatacag cttaaaagct aacagtcaca
    16441 aattttgaaa gtaatataag tatttatcaa taagagtggt aacgcggtaa agtcgtctct
    16501 tagtcattaa agactgagag actttttttg taactcgaaa catttaagta ttaaaatctg
    16561 agggaaatta taattaaaag agaggggtag ttaaaatgaa agtatttaaa aaattattaa
    16621 gtttaggatt agtattagga ttgacattat cgctagtagg atgtagtggt ggaggagaaa
    16681 aaacaaagtt agaacaaata aaagacaatg gaaaattagt tgttggtact agtgcagaat
    16741 ttcctccatt tgaatttcat aaggtagtag atggaaaaga ttcaataaaa ggattcgata
    16801 taatgttggc tgaagaattt gcaaaagagc ttggtgtaaa ggttgaaatt aaggatatgt
    16861 catttgatgg attaataggt gctttaaatg cagaccaagt tgatattgtt cttgcaggta
    16921 tgtctccaac accagagaga gaaaagagtg ttgatttttc agaattatat tatttaagta
    16981 gaaatgcagt tatagttaaa gatgcagata tagacaaagt aaaaactgaa gatgatttaa
    17041 agaaacttag agttggagtt caagcaggaa gtatccaaga agaatatgta gttaacactt
    17101 taaaaatgac aactacaaaa tctttgaaag caatacctga tttaattaca gaattaaaaa
    17161 atggaaacat agatgcagtt gttactaatg aagcagtttc tttaataaat gttaaaaaat
    17221 atgatggaat aaaaatggca aatactgaag ttgggaaaga tgtaacagaa ggtatggcag
    17281 cagcaatcaa aaaatctgac aataacaaag attttataga attattaaac aaaaagataa
    17341 aagaattaca agatggcaag aagatagaag aatttttaaa tgaagcatct actgaagctg
    17401 cttcaaatta gtaagaaagt tatgtgggag atgaaattat gagtttagat tttagttttt
    17461 taagtagatt tgggacttct tttttggaag gaacaggtgt gacagtatca atttctcttg
    17521 tggcattatg ctttggattt ataataggta taattatctg tatggcaaaa atatcaaaga
    17581 gcaaagtatt aagagcaata tcatcaatct atattgaggt tttaagaggg acaccattat
    17641 tagtacagat atatatagta tggtttggtt tacctcaatt aggaataaga ttccctatgt
    17701 tgtttggtat accaagtgaa tttatagcta gtgcatttgc attatcagta aactctggtg
    17761 catacgtggc agagatactt agatcaggta tacaatcagt tgataatgga caaatggaag
    17821 caagtagatc attaggatta aattattggt caactatgag atatataata atacctcaag
    17881 ctataaaaaa tatattacct tcattagcaa atgagtttat tacacttgta aaagaatctt
    17941 caataatatc tgtaatagga gttgttgaga taatgcgtac tgctgatata gtaaaaaatg
    18001 cagcatttag agcattagag ccattaatag tagcagcagc aatttacttt gttataacat
    18061 ttactctatc aagattagtt ggattattag aaaagaaact atctgtgtct aactagatga
    18121 gagcatgttt agcatttagg gaaaacatag aatagtaaaa aggaaagtga taatatgatt
    18181 acaataaaaa atttaagtaa atcttttgga gatttaaatg tattaaaaaa tatagactta
    18241 gaaatcgcta aaggcgaaat aatggttata gtaggtccaa gtggttctgg taaaagtaca
    18301 cttcttagat gtatgaattt actagaaata cctacaggtg gagaaataat atttgaagga
    18361 aaaaatttgg tcgataaaaa aactaatatt gatgaggtta gacaaaatat aggtatggtg
    18421 tttcagaact ttaatttatt cccacataag actattttag ataatataac attagcacca
    18481 attaaattaa aaaagatgac taaggaagaa gcagaaaaaa aagcagaaat tttgttgagt
    18541 agagttggtc ttttagataa aaaagattca tatccatcac aattatctgg aggacaaaag
    18601 caaagaatag caatagctag agcacttgct atggaaccag atatgatgtt gtttgatgag
    18661 ccaacatctg ctcttgaccc agaaatggta aacgaagttt tggatgttat aaaagaactt
    18721 gctaaagaag gtatgacaat ggcaattgta actcatgaga tgggatttgc taaggaagtt
    18781 gcagatagag ttatttttat agatggagga agtatacttg aagataatac tccagaagaa
    18841 gttttcggaa atccaaaaca tgaaagaaca aaagcgtttt tagcaaaagt gctataatat
    18901 ataaaaagga tgttattgat attagaaatt caatacatcc ttttttagtg atggttaata
    18961 ttaattttaa aattaaagtt atattaatat taactttatt tttacgattt tttgcagaaa
    19021 aaaaaagagc tcggggtaag ctcttttttt ccaccgaatt aatttccgtt actaatccga
    19081 tttttaataa atataaaata tatccttatg aaagggtatt gggaatagat atattaacta
    19141 actagggtta ccagggggat aaccttaatt tattataaca aaatgcgaca caaaaatcaa
    19201 tatttttttt gaaataaatt ataaaagtta tttttataac aagtaagctt ataaatttaa
    19261 cttttatagt aaaaataagt atatgtataa tataatatat ttattttata taatatatta
    19321 ttttatcata tattgtattt tataatatat ttttgtaggg tatagtataa gtatattata
    19381 ttttactata aaaatttgta ataaagtgaa aaaactagct tttcatgaaa taatatttta
    19441 taatttaaga ttgtcttttt aataaagatt aacaaaaaaa atactataat tagtggtata
    19501 atagttagag ttgaagattt taaataaagg taggtgtaat taagttggaa atatacttag
    19561 acaatagcgc aactacaaaa ccttatcaag aagttataga taaaatggtt tatgcactta
    19621 atacggaata tggaaatcct tcttctgtcc atagaaaagg tgtagaagtt gaaaaagcta
    19681 taaaagaagt aagacaagat atagctaaat ctctaggagc gaaagaaaag gagatttatt
    19741 ttacatcagg tggtacagag tgtaataata ctataataag aggtattact agtttaaata
    19801 aaaaaagaaa aaatcacata atatctacta acatagaaca tccttctgtt ttaaatacat
    19861 taaaagattt agaagaagat ggttttgaag taacttattt agaggtcgga aaagatggga
    19921 aaataaatat agaggattta aaaaatgcga taaagtcaac tacatgctta gtaagcatga
    19981 tgcatgttaa caatgaaata ggaactatac agccaatagg tgaagttgga aagtatttga
    20041 agggtttaaa agaaaaaatt tatttccatg ttgatgctat tcagtcatat ggaaaaatta
    20101 attttagact atctaaatac aatatagatt ttatgagtgt aagtgcacat aaatttcatg
    20161 gtccaaaggg aattggattt atgtatataa aagaaaataa tcgccttaag cctatgttaa
    20221 caggtggtgg tcaggaaatt ggaattaggt cgggaacaga aaatgtacct ggaatatatg
    20281 gtcttggaga agctgttaga atactaaaca aagatttaga tgttgttatt tcgaaagtaa
    20341 ataacttaaa aaatatatta aaaaatgaaa taattgataa tatagaagat ataaaaatta
    20401 attctccaga agatggagta tgtcatatat taaatgtatc atttagaggg acaaaaggag
    20461 aagttttact tcattactta gagcaaaagg gtatttatgt atcaactggc tctgcatgtt
    20521 cttctaaaaa gaaaggtagt tacgtattaa atgctatagg tcttacaaat gaagaaataa
    20581 atggaacaat aagatttagt ttatctgata tgaatacaga agaagaaatg ttagaagctg
    20641 tgaaagtttt gaaagaatca atttgtgact taaggtcaat aatgaaaaga aaataaagaa
    20701 tactgtatag atagtgataa taaattagtt taagaggtga aatggtgtat aatatattaa
    20761 tagtaaagta tggagaaatt ggagtaaaag gaaagaatag atatatattt gagaataggc
    20821 ttataagaaa cataagaaat atgttaaaac caattggaag atttaatgta tataaagagt
    20881 atggaagaat atatgttgat ttagaagact atgattatga agaagtaatt gaagaagtta
    20941 gaaaagtatt tgggatagtg ggtgtgtgcc ctggagtaag agctaaaaaa gattatgata
    21001 cattaaaaga aatagcttta aaaatgttag aagaaaaaat agaggctgga tataaaactt
    21061 ttaaggtaga gtcaagaaga ggagataagt ctttcgggtt gacttctcaa gaaatgagta
    21121 tggatatagg tggatactta ttatcaaagg taggagatag gattaatgtt gatgtaagaa
    21181 atccagaagt taaaataaag tgcgaataca gagaatttca tactatggtc tatagtgata
    21241 ctatacctgg atatggtgga ttgccacttg gaacgaatgg tagagctatg tctcttttat
    21301 caggaggtat agatagccca gtagctacat ggatggttgc aaaaagaggt atggaagtag
    21361 aggcagttca ctttcatagt tatccattta caagtgaaag gtcacaggaa aaagttaagg
    21421 atttagctaa aatactggca aaatactgtg gtagagtaag gcttcataaa gttaatatct
    21481 tagaaataca aaaagcaatt ggcgagaatt gtaatgaaga agaagctact attctttcaa
    21541 gaagatttat gatgaggata gcacagagac tttctgaaaa aagacattgt gatgctttaa
    21601 ttacaggtga aagtattggg caggttgcat ctcaaactat acaaggactt acttgtacta
    21661 atgccgttgt agacttacca gtgtttagac cacttatagc aatggataaa tcagatatag
    21721 ttgatatagc caaaaaaata gggacttttg aaacatctat attgcctgaa gaagattgtt
    21781 gtagtgtatt ttctcctaga aagcccgtca ctaaacctag attagagaaa atagaaaaat
    21841 ctgaaacagc acttgacatt gaaaaattag tacaggatgc tattgacaaa atagaggtag
    21901 aggatattga gttttagcat acaagttatt taattactaa attgaatatt gagtatatta
    21961 gtagttctgt aagtatatta gtagttctgt tgaaaggatt tatgtagaca atttattaat
    22021 atgtagtatt taaaaataag tactataatt ttatttaatg ggaatgatta ttatgaataa
    22081 aaagggtttt acactaattg aattgttagt agttatatct ataataggca ttttagttat
    22141 agtagctgtt ccagcattgt ttagaaatat agaaaaaagt aaagcagtta catgtctttc
    22201 taatagagaa aatataaaga ctcaaattgt tattgcaatg gctgaggaat caagtaaagg
    22261 caagaatgaa gtcatgaaag aggtattaga aaacaaagat ggtaagtact ttgaaacaga
    22321 accaaagtgt aagtcaggtg gaatatattc agcaacgttt gatgatggtt atgatggaat
    22381 aactggaata gaaagcattg caaaagtgta tgttacttgt acaaaacatc cagatggtgt
    22441 tgaaatggct agggatatac atcaaagtat gaaagatttg attgcatcat tttcacaaga
    22501 cccttctata ataccaggag cctcaaaggg taatgatgat tttagaaaat atttattaga
    22561 caataaatat aaaaatgggt ggcctacaat tccagatgaa tttaaggcaa aatatggatt
    22621 aagtaaggat acactatata tacaaccata tgcatatagt cctactaaat ctgatgctac
    22681 tgtagttgta tttgcaaata ataagactgg gggtaattgg tatacttccc tagtttacga
    22741 ttatgatgaa ggtagatggt ataaaggtaa aaatggtatt tctgttgcag gtaggtcatg
    22801 ggatgttgac acagatagtg ttaagtctgt aaaaacagag attcattcta aagagggatg
    22861 gggtccttta aattaatata tcatgtttta ttaatctggt attgattaaa ctatagaaaa
    22921 gagcagtttc tatagatgac gaataccaga ttttcattta tatatataat tgagatatat
    22981 taaaagtgtt tatattttta agtcttcaca tacaagctaa aaataattat aataatattg
    23041 taaagaaatt taattataag attaattttc tgaagattta gtatttgtac taagaaatac
    23101 ataaaaaggg gaatagatat gaataataat tttcaagaca accaaacaat aaatttaata
    23161 caaagtcgta gaagtatacg aaaatttacg acagaacaaa ttagtgatga gcaagtaaac
    23221 acattattac actgtgcatt tgcagcacct tcaggatgta ataaacagcc ttggcacata
    23281 actgttgtgc aagaccagaa acttttaaaa gagattagtg atgatacttt atctaggatt
    23341 catgaggtga gtaatgttga gataaataaa aactttaagt tattttatgg tgctccaacc
    23401 gttttattta tttcttatga tgaaagtagt tcatgggctc catatgatat aggaatactt
    23461 acagggaata taacaacagc tgcacaagca ctagggcttg gaagttgtat aataggaatg
    23521 gttagaggtt tatttacacc tgttgaacaa ggggatattg aaggtcttgt gagtgtattg
    23581 gataaagaag atgtaaaaga atcagagtca ataaagatga agtttgatac aaataaaaaa
    23641 tacagagaac tacttgatat accagaaggg tattctgtac catttggtat tgctgtaggt
    23701 attccagatg gaaatttacc aaatgctaga gaggtagttt ataaagtttc cagagtttag
    23761 gataaagtat tgcaagaacc aatcagttac ttgaagaatt aaaccagtaa tatacaaata
    23821 aattgatgga agaggaagct atttaaaaag tagtttagat ttttcgttgt aaaataatta
    23881 aataaagaat aaggtgataa gtattttatt tattatctta ttctttttta tttttgtttt
    23941 gtagaatgat aaaaataagg attaagtgta ataaaataga aaacaagtat gttaatttta
    24001 agtatatgct ttaaaattta tccaagttaa aaatttaaga tatcttttca gtataatgga
    24061 aaaaatgtca aaatattgaa atagggaaaa aatagtgata taataagaaa aaatagagaa
    24121 aaa
//
LOCUS       DAEPKC010000057        24016 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.057, whole genome shotgun sequence.
ACCESSION   DAEPKC010000057 DAEPKC010000000
VERSION     DAEPKC010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 24016)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24016)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24016
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.057"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     regulatory      144..245
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            318..1661
                     /locus_tag="KR294_002315"
     CDS             318..1661
                     /locus_tag="KR294_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HBH0240389.1"
                     /translation="MVPNTNNVQPGGNNSSLSFLDKMFKFSERGSSLKTEVIGGVTTF
                     LTMAYIVFVNPAILSEAGMDKAALITVTILATAIGTLIFAILGNAPFALAPGMGLNAF
                     FTYSLVIGAGIPWQTGLGVVFLSGCVFFTLAVTGLRKTIADAIPRELAVASSAGIGLF
                     LAFVGLKNMGVIIANPDTIVSLADFTPTVLIALFALILMAILEYKKVKGGILISIVVA
                     TIISVIFGFVELPTAIISTPPSIAPVAFKLDIVGALKFSLIGPIFSFMFIDMFDSLAF
                     LITCCKQMGLEDENGEIKDLGRMLYADVSSTLIGSFLGTSTVTTFGESASGIAAGART
                     GLASIVTAALFLATLIFTPLLGIVPTYAAAPALVMVGVFMFESIKQIDFADSKIAVPA
                     FVTVLLMPLTYSISIGLCFGFISYIIMHVVAKETDKISITLWIIGLLAVVNLVLS"
     gene            1840..3204
                     /locus_tag="KR294_002316"
     CDS             1840..3204
                     /locus_tag="KR294_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH0240390.1"
                     /translation="MSQLLIKNAYLITMNADREVYENGSILIENNIIKEVGKFDINIV
                     DKDAEIYDAKGKILMPGLVNTHVHLSQQLGRGLADDVVLLTWLRERIWPYESSFNYED
                     SLISSTACCVELIKSGVTTFLESGGQYVDAMVEAVDKTGLRACLAKSVMDTGDGLPEA
                     WQKTTDEEINTQLDLFHKFNNTSNERIKIWFALRTIFNTTEELLVRTKELADKYNTGI
                     HMHIAEIADEISFVKQNNGVGTVEYLDKLGVLGPNLLAAHTVWLTHKEIDLFRLHDVK
                     VSHDPGSAMKVVLGFASIPEMLEKGIPVSIGTDGAPSNNRMDLMRDMYLTSLIHKGRT
                     LNPTVVPAEEVLEMATINGAKCALLEKEIGSLEVGKKADMIILNPDTIHCLPMHNPIG
                     NIVYSMTSENVDSTICDGKWLMKERKVLVVDESELLNKVKKQASKIKDKAEVKIPSKF
                     KIIK"
     gene            complement(3382..5247)
                     /locus_tag="KR294_002317"
     CDS             complement(3382..5247)
                     /locus_tag="KR294_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIRAN domain-containing protein"
                     /protein_id="HBH0240391.1"
                     /translation="MENVFKRLQEFNGYDGYKESFEMNYLCIYESIPLREQVELANNL
                     VDEILNMYKSESNEIYLLEGSNSKSLICYFEIFMKKINTLVKEMIIDEKWLYKLTKEL
                     IYKSKKVEYVKLGLVLSEKYLNVENLREVVDTFSKSGEYVFYLSNTIKKLEFYNTYLF
                     NLSKKATGSIKVFAIVNMENLDSKINSYLIEDGYKDTKYERLLMNYIISIVDLNEYLE
                     KRDLDKEKINNLARLICNYLLSVEFKYIGNKLELVNRFLPTVVNYGTNFESLYSIFLI
                     AINVLKDENIECNKIEFEKEINGILLSEKWKNIYFEALRDASGKTEDIIKMSEIYDVN
                     LSFDDLLPYLNRDIRDFEVYWHISKKGTTSSRLKLLNFFEETFKIDDLIGKMKDIEKD
                     KLTQEYYDDMLFFIVLKGSKSLYPEGKNISLKGIFGNINEVRKESINILKRYREKLSL
                     EELKIVKEAYEKEKNVILKDELRRVLYESNNLKKEFVNIEKIKVDEHGKDIYLTSIAV
                     AGSRFRNREYLEKELEKSKIYYLTREKDNLYDEKAIKIVGETGYVIGYVPRKENYILS
                     NLLDGGKLLYCRVTEYNLYEDCIYANVYLSYKDVIETVENSLKMVLDKSRIKLIN"
     gene            complement(5483..6700)
                     /locus_tag="KR294_002318"
     CDS             complement(5483..6700)
                     /locus_tag="KR294_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH0240392.1"
                     /translation="MNNKKYYPTAIALYFSYFLLGIGISILGQYKPEFSSMWGAKTLS
                     DGTLDVSIVLAVIAALGLGRLISYPFAGPISDKYGRKVSGLIGNFLHAIFFVGIVFSP
                     NFYIAYVFAIIGGAANSFLDTCVTPSCMEIFASLGTIANMFTKFTIALAQFLLPFIIG
                     FVAANSISFKVIFIVTAILIVVDAFLIAVLPFPPANNVIDNKGKTVKSEKMKFTPTSI
                     ALVCIGFTCTSTFVLWLNCNQELGKLYGMADPTKIQSFYSMGVICAVLITSLLIKKYI
                     KPIRILVIYPIIALLMLLVVYFVQTPTICMLGGFVIGYSAAGGVLQLTTSTANEMFPT
                     NKGKITSIVMIASSIANYVILNIAGIITKSGGVNGPKYVVLFNVAITFVGILLALFVN
                     MRYEKEKVYDYDV"
     gene            complement(6900..7763)
                     /gene="aroE"
                     /locus_tag="KR294_002319"
     CDS             complement(6900..7763)
                     /gene="aroE"
                     /locus_tag="KR294_002319"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HBH0240393.1"
                     /translation="MEISGRTGLFALIGTPVGHSKSPVMYNYSFKKLDLDYRYLAFDI
                     TVDKVKEALLAIKTFNIKGANVTMPCKSAVTEYMDELSPAARIIGACNTIVNDNGKLV
                     GHITDGVGYVRNLKENGVEVKGKKITIMGAGGAATAIQVQCALDGAREISIFNPKDDF
                     YKRAEQTVENIKKDVPECVVNLYDLEDTNKLYEEIQSSDILTNATLIGMKPYDNETNI
                     KDTSVLRKDLVVTDVVYNPKKTKMIEDAEANGCKAIGGLGMLLYQGAEAFNLYTGLEM
                     PVEEVNELCFK"
     gene            complement(7845..9767)
                     /locus_tag="KR294_002320"
     CDS             complement(7845..9767)
                     /locus_tag="KR294_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBH0240394.1"
                     /translation="MKISSMFTPIRIGSMTVPNRFVVPPMGNNFANTDGTLSETSKAY
                     YLERALGGFGLITIESSVVDKKAKGGPRKPCLYDDSTIDSFKNVIDACHDAGSKVSIQ
                     LQHAGSEGNEKVAGHPLKAASAIPASNGRNTPLAITTEEIYELIESYGDAALRAQKAG
                     ADAVEVHCAHGYLVSSFISQRTNKRVDEFGGCFENRMRLPRLIIENIRKKVGNSLAIL
                     CRINSTDDVPGGIDVHDSSVIAAYLEDCGIDGLHVSRSIHIHDEYMWAPTTLHAGFSA
                     ELVTEIKKAVSIPVITVGRYTEPQFAELMVRQGRCDLVAFGRQSLADPEMPNKAKNGK
                     LDEMIPCIACLQGCVPNMFQGKPIACLANPILGHEAELKPAEISKEVLVVGGGVGGML
                     AAWVCAKRGHNVTLVEKSEVLGGQMRLAAYPPGKGDITNLVRSYISKCNQYGVKICTN
                     TEATVELIKEKSPDVVIIATGATPLVLPIPGINDSGLIHAVDLLDGKKSCGKKVLVVG
                     GGMVGCEVAAFLGEQEHEVTVIELREEVGADVISEHRKFLMNDFENYNIHTITGAKVS
                     KFYDDGVDYLLTDGTEHDLKGFDSVVLAMGSRNYDPLSEVIKEVVKETYIVGDAVKAR
                     RALDATKEAFEVALNI"
     gene            complement(9831..10679)
                     /locus_tag="KR294_002321"
     CDS             complement(9831..10679)
                     /locus_tag="KR294_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HBH0240395.1"
                     /translation="MNNQKNLNIPITISSYTLGTEVSFRDRVRIAKEAGFDGIGLRAE
                     NYIDAKNAGVTDEEMIAILNEYDMKVTEVEYITQWGREEDRTEAQREKEQNVYHMAHL
                     FNVKHINCGLLEMIPEEQIITALGELCDRAGELIIGLEFMPYSGVPDLATAWRVVKGC
                     NRENAMLILDTWHWARAKQTAEDLAPVPADKIVSIQVCDVLETPYEKLRDESLHDRLA
                     PGEGYGNTEEFVKIIKEHNISPRVIGAEVISDSLISKGLSTAAETVFNATKKVLDKAW
                     SEVSPK"
     gene            11092..11973
                     /locus_tag="KR294_002322"
     CDS             11092..11973
                     /locus_tag="KR294_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBH0240396.1"
                     /translation="MNLYHLRYFVTLAHLEHYTKAAENLSITQPSLSHAISLLENELG
                     VALFEKEGRNIVLTKYGKIFLKDVEKSLEILDSSVKSLKITGTGEGQIDLAFLRTLGT
                     DFIPDIVHKFLKSNPAKSIDFKFHTGVTTDIIQGLKERKYDIAFCSKLEKEKGIEFIP
                     VAKQDLVLIVPYSHPLAAKDTIDLKETIPYPQIVFNQRSGLRYIIDDMFKKINQQPNI
                     VYEVEEDQVIAGLVAKNFGIAVVPNMNMLSFTKVKVIQIIHPSWERNFYLAFIKDRYL
                     PPAIKNFKNFVIKNAQL"
     gene            complement(12181..13044)
                     /locus_tag="KR294_002323"
     CDS             complement(12181..13044)
                     /locus_tag="KR294_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3800 domain-containing protein"
                     /protein_id="HBH0240397.1"
                     /translation="MLSSYVKRVSKIIKKKYIMFIDESGRADINHEDPFTLTGVIFEY
                     KYAVSQGDYVCSLRKEMDAFKEYCFGTSNIGIHLTDISRKSRAFEKFDDSQIKLFYDE
                     LPLFLSRLECTIISVTVDKARLKKYYAPSKEPYVVAFIHVLQNFYSFVNNETVESARI
                     VIESRDDVSNLKVQKAFFDVFNNGTIYLDIDEELRDKVKGFIIAKKEDADYREGLEIA
                     DILCNPLSRARRGLIEANPKCMQYGEKNKIFKSVRNKIYTPTSVNDIRNWGFKEVPIV
                     EPVGPWLEKMR"
     gene            complement(13199..15133)
                     /locus_tag="KR294_002324"
     CDS             complement(13199..15133)
                     /locus_tag="KR294_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp22"
                     /protein_id="HBH0240398.1"
                     /translation="MKKSLKKYLVLALTLVLVFACGVPESSAASKHVIIVNSRKNTLG
                     YFVNNKLVKEFRVATGKKGSETPTGKTKVVNKIKNRPYYKGNIPGGSPRNPLGDRWMG
                     LALKGTYGDTYGIHGNNNESSIGKHISGGCIRMHNKDVRWLFDQVPVGSDVIIDYSND
                     SYVKIAAKYKINLNQTGWKTENGKKYYVKSDGTYQKNSWLKVNGKMYYFDASGVMQTG
                     WKTINNKKYYLGTDGARVSGWKVIDGKTYYFNSDGVMQTGWQEKNGKKYYLGSDGLAV
                     TGWQEIDGNKYYFDKTGIMQTGWQQIDGKSYYLDKDGKMLTGSQKIDGKDYTFNEDGT
                     INPTWDTIIGANRFDTAKKISSVGNWNADSSDTVILVNGNAIADGITATPLASSYDST
                     ILLTNTANLPTETVEEMKLLAPKTVILIGGENAISSKLEQEIKTTFNTETKRIAGQDR
                     YQTATRIAEELGNREEIKTAYMVSGNGEADALSVASKAGEEKQPIILVNKDGITEESY
                     KWLTERKLENAYFIGGPSAINDSVIAKMNDITTEDISGNRIYGDSRVDTNAKVIEKFY
                     GDTDLQAVLVSKSDALVDALSAGPLAVKLHSPIVLMDNSGLSSEQQRVFANKKVETPY
                     QIGGGVSYIVMDKLMDILAK"
     gene            complement(15245..16258)
                     /gene="galE"
                     /locus_tag="KR294_002325"
     CDS             complement(15245..16258)
                     /gene="galE"
                     /locus_tag="KR294_002325"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HBH0240399.1"
                     /translation="MAVLVAGGAGYIGSHTAIELLESGYEVVIVDNLSNSNSIVVDRI
                     KELSKKPVKFYNIDIRNKDEMHVVFKENNIESIIHFAALKAVGESVEKPIEYYSNNLI
                     STLNLFELMREYGVKKFVFSSSATVYGDPHTCPILEDFPLSVTNPYGRTKLMIEQMLV
                     DISKADKSLDIALLRYFNPVGAHKSGRIGEEPNGVPSNLMPYITKIAVGKLKELSVYG
                     NDYPTHDGTGVRDYIHVLDLAAGHVKALQKLEENPGLVVYNLGTGKGYSVLDLVKAFS
                     KASGKEIPYKIVGRRAGDVAMCYADSSKAEKELGWKAKYELEEMCEDSWRWQSMNPNG
                     YEE"
     gene            complement(16282..17151)
                     /gene="galU"
                     /locus_tag="KR294_002326"
     CDS             complement(16282..17151)
                     /gene="galU"
                     /locus_tag="KR294_002326"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HBH0240400.1"
                     /translation="MTVKKAIIPAAGLGTRFLPATKSQPKEMLPIVDKPTLQYIIEEA
                     IESGIEEILIITGRNKKSIEDHFDKSVELELELEQKGKTEMLEMVRDISNMVNIHYIR
                     QKEPKGLGHAIYCAKSFIGDEPFAVLLGDDIVDSDVPCLKQLIDTYNEYKTTVLGVQK
                     IAKEDTNKYGILDVKHIEDRVYKVKDMVEKPAIEEAPSDIAILGRYIITPAIFSILEK
                     QTPGKGGEIQLTDALQTLGKQEAIYAYNFEGRRYDVGDKIGFLEATIDFALKRENLKD
                     DLMDYMRKKVSEK"
     gene            complement(17349..17669)
                     /locus_tag="KR294_002327"
     CDS             complement(17349..17669)
                     /locus_tag="KR294_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240401.1"
                     /translation="MSSKYNVWTFNYEFLGLDSGDEKNNEVYYEIDLDEILNENYIDE
                     DIDSGLDSDGNSILGELISEMDIDEDVSVDMTYQELEVDLEDLDSYLDEDIDSDIKGI
                     LDEI"
     gene            complement(17659..19650)
                     /locus_tag="KR294_002328"
     CDS             complement(17659..19650)
                     /locus_tag="KR294_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240402.1"
                     /translation="MLKLGEKIIYELSDGFELSGISRYSKEYKKLHITNLGNIIISKS
                     DEVNEDTGVKYIYSFSDNKEKLEAVLEDSQIIVYGNNLPFYIKSENSSKNVTANLTMK
                     ITLDEYDLICKSQREFIFYLKDNMTILSLDDNKFYMGGINKDNEKFIFISGKNRFEIN
                     FDDIERYILEDKRVSLKGYFHMEREGIIVRSVSIFNNNIDSVVPSDLNERVKDNQKIG
                     NLPKDCEIVFCKISGNIDGFDYKNTNMLLVKYQDQLIFINKKSKKTIVKSAKDNCSKL
                     NLGEDIILYDNKNVFNLHINDKNREIMQIDDLKDIENEIVGYTLKHAPFFIQEDFDSL
                     TILKSFQKEIISIKNSDIKDIVINKELENENSNFVETEIKFNNQKVLLNLSKSMVQKL
                     MQDVFIYAKQPLLKENSIEVIYKNWSKAMNDMIIFNFFGNIYYMKSEFDKILEKELND
                     EIRIEVINSLYKQIQEQRNNLDLLSAYMPRILENQEIDLFEKYNTKLDVQVFKQIKNL
                     LSDLSYNISSYLNEVEKSLDNIIFVISGEDKKKYNYRMLKESESASLDVFLKQAISRL
                     NHLVENMYPYYVDETSREMFKLFELLWKNYRNIDDDSIKEILFERITNTYVFKQLTLN
                     NSTKERRKDIIEKIYNSVDYGTNKLDENMFFTGGIKYVK"
     gene            complement(19773..22316)
                     /locus_tag="KR294_002329"
     CDS             complement(19773..22316)
                     /locus_tag="KR294_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPOR domain-containing protein"
                     /protein_id="HBH0240403.1"
                     /translation="MKVLSENNIIRNTVLNVTASFLKQESKINEKLDGVLEKKFEKVE
                     FNEAKYAELLKFNILFYKTLARNTEPLIGKWIVDKYIPEIDELEKDLELTTAKCRKYV
                     NKAMKEGLDSLKANDLNSFLAYDKMELSERRRRLEKDYKVLNLYKDLLNISLRKISLE
                     KKECGDLFLKNQADAKRELKREIIFCVNKILASNKDVVPNNVEENNEQNKVEIKATEI
                     EDLQLGKDNSENDMLLNEIKNSKVKHESKSNDIESKFIDKLNSLNNESISQTIHNEYK
                     KLCGLEELHSVEAYGFGKEIIKDFACATVVLEFLKRRNRDLIEGAMRLTIIGEFGPEN
                     FKEFVDYVIKNKTEISEDTWNKAQNLIKDNYSELENHEIASKRTRRNKDIDIEEYIYM
                     IKNADKDICFRSSISIEDDAEEGTKEEVDSNNQDIGDVVEDKDTTDKEYDSNKEDIIE
                     PENKKSKKKAKLFGFIKKDNEEAEQEEENLNDISPDIILDKPVENHQVKSEEIEQNEL
                     KEIKQEEPSQHIEEERSVKIEKPINNNLDEKVSSNNESKLEKESKNLEDKKAKEIKEE
                     KLENEKSVVIPIKKKENSNKKSKNSSKDKYRENKKEMKNYVSDKEDSLDDEEVVSKKS
                     RLKETIIAVVIVVIVGVGYFITVGNNKKNDKENIPKSSTQQQANNKLTEEEKKAQAEK
                     EKKEAEEKAKAEKEAQEKAQAEKKAKEMEAYKDGKGVYYTVYAGSLKVEKTAKETAKE
                     YEAKGISSTIIQENGYYKIKIGDYSQYGEAQEKCNELAKKSIDTYIAMYDKYYDYKLE
                     ELKESAPSLSAEELKQKYEDLRSELKNKSGYREYVKHLDKLYEEIVEGA"
     gene            complement(22594..22928)
                     /gene="rnpB"
                     /locus_tag="KR294_002330"
     ncRNA           complement(22594..22928)
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="KR294_002330"
                     /product="RNase P RNA component class A"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00010"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00010"
     gene            23060..23737
                     /gene="srtB"
                     /locus_tag="KR294_002331"
     CDS             23060..23737
                     /gene="srtB"
                     /locus_tag="KR294_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtB"
                     /protein_id="HBH0240404.1"
                     /translation="MKKLYRIVINIILVLVILYSGFNIYSKLTKYNHDTKISSELQKK
                     EYKKEDLSKINSDFKFWLSVENTNINYPVVQSKDNSYYLDKDFYKKDSISGTLFMDYR
                     NKSIDDKNIIIYGHNMKNKTMFNNLNKFKDADFFKKNNKIKITLNGKEFLYDVFSAYI
                     VESDYDYLKTNFNNESDYQNYINDITSKSLYKSPIKVNSNDKIVTLSTCTYEFDDARM
                     VIHGRLI"
     gene            complement(23897..23971)
                     /locus_tag="KR294_002332"
     tRNA            complement(23897..23971)
                     /locus_tag="KR294_002332"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(23937..23939),aa:Thr,seq:tgt)
BASE COUNT         7667 a         4153 c         2709 g         9487 t
ORIGIN      
        1 gacattatat tcatacatat tcaattattg gaaaaagtaa tttttttcaa taaataacct
       61 taatttttta taaaatcgac aaaaaaacga ataattttat tatatttatt gtaaataata
      121 caatattacg atataataca acagaaaaac aaatagaaaa tgttcatata atattagtaa
      181 tacggtctaa tagtttctac aaactcacct taaatgggtt ttctatgaat agaatgtcaa
      241 ctctgaatat atgttctatt ctatctatat gaatatatat ttttttgttt atatcttaaa
      301 gttttttgga ggtaaaaatg gtaccaaaca ctaacaatgt acaaccaggt ggaaataatt
      361 catcattaag ctttttagac aaaatgttta aatttagcga acgtggctct agccttaaaa
      421 cagaggtaat aggtggagtt actacatttt taacaatggc atacatagtt ttcgtaaatc
      481 cagcaatatt atctgaagct ggaatggata aagccgccct tataacagtt accatactag
      541 ctacagccat tggtacactt atatttgcga ttttaggaaa tgcaccattt gctctagctc
      601 ctggtatggg attaaatgca ttcttcacat actctttggt tataggtgca ggaatcccat
      661 ggcaaacagg tcttggggta gtttttctat ctggatgtgt cttctttaca ctcgcagtaa
      721 caggtcttcg aaagacaatt gcagacgcaa ttcctagaga attggcagta gcatcttcag
      781 caggtatagg tcttttcctt gcttttgttg gtttaaaaaa tatgggtgtt ataatagcta
      841 atccagatac tatagtttca cttgcagatt ttacaccaac agttttaata gctctttttg
      901 ctcttatctt aatggcaata ctagaatata aaaaagttaa aggtggaata ttgataagta
      961 tagtagttgc aacaataata tctgttatat ttggatttgt ggagttgcca acagcaataa
     1021 tctcgacacc tcctagtata gcaccagttg cttttaaatt agatattgta ggtgcattga
     1081 aattctcatt aattggacct atattctctt tcatgtttat agacatgttt gattcattag
     1141 catttcttat tacttgttgt aaacaaatgg gtcttgaaga tgagaatggt gaaataaaag
     1201 atttaggaag aatgttatat gcagatgttt cttctacttt aataggctca ttcttaggaa
     1261 ctagtactgt tacaacattt ggagaatctg cttctggtat tgcagcaggt gcaagaacag
     1321 gacttgcttc aatagtaaca gcagcattat tcttagctac acttatattt acaccattac
     1381 ttggtatagt tcctacttac gctgcagctc ctgcacttgt aatggttggt gtattcatgt
     1441 ttgaaagcat aaaacagatt gattttgctg atagcaaaat agctgtacct gcttttgtta
     1501 cagttttatt gatgccttta acttatagta taagtattgg tttatgcttt ggatttattt
     1561 catatataat aatgcatgta gtagctaaag aaactgataa aatcagtatt acactttgga
     1621 ttataggttt acttgcagtt gtaaacttag ttctaagtta atatttttaa atagttctag
     1681 gtcaatattt taaattatat agaataaaat cttatttatt ttaaatttat aaatagcaaa
     1741 atcactttat atgtaaattg attttgctat taactttgta tagaaaattt attatcataa
     1801 tatatagata taaaaatata tagaaaagga gtggtgttta tgtcacaatt acttataaaa
     1861 aatgcatatc taattactat gaatgcagat agagaggtat atgaaaatgg aagcatactt
     1921 attgaaaata atattataaa agaggttggt aagtttgata ttaatattgt agataaagat
     1981 gcagagatat atgatgctaa aggaaaaata ctaatgccag ggctagtcaa tactcatgtt
     2041 cacttatctc aacaattagg acgtggtctt gcagatgatg ttgtactttt aacttggctt
     2101 agagaaagaa tttggccata cgaaagtagc ttcaattatg aagattcctt gatttcatct
     2161 actgcatgtt gtgttgaatt gataaaatct ggtgtcacta catttttaga atctggtggt
     2221 caatatgtag atgctatggt tgaagctgtt gataaaactg gacttagagc ctgtttagct
     2281 aaatcagtta tggatacagg agatggtctt cctgaggcat ggcaaaaaac tactgatgag
     2341 gaaatcaaca ctcaattaga cttattccat aagtttaata atacatctaa tgagagaatt
     2401 aaaatatggt ttgcattaag aactattttt aatacaactg aagaattact tgttagaact
     2461 aaagaactag ctgataaata caatacaggt atacatatgc atattgctga aatagctgat
     2521 gaaatttcat ttgtaaagca aaacaatgga gttggaacag ttgaatacct tgataaacta
     2581 ggtgtattag gaccaaatct tttagctgct catacagttt ggcttactca taaggaaatt
     2641 gatttattta gattacatga tgtaaaagtt tctcatgacc caggttcagc tatgaaagtg
     2701 gttctagggt ttgcatcaat tcctgaaatg ttagaaaaag gaatacctgt ttcaattggt
     2761 actgatggag ctccttcaaa taatagaatg gaccttatga gggacatgta tcttacatca
     2821 ctaatacata aaggaagaac tttaaaccca actgtcgtac cagctgaaga agtcttagaa
     2881 atggctacta taaatggagc aaaatgtgct ttactagaaa aagaaattgg tagtcttgaa
     2941 gtaggaaaaa aagctgatat gattattcta aatccagata caattcattg tttaccaatg
     3001 cataatccaa ttggaaatat agtttattct atgactagtg aaaatgtaga ctctactatt
     3061 tgtgatggta aatggttgat gaaggaaaga aaagtattag ttgtagatga atctgaatta
     3121 ttaaataaag ttaaaaaaca agcttctaaa ataaaagata aagcagaagt taaaattcca
     3181 tctaaattta aaattataaa ataacataaa tttcaattgt tttgtaaata tgaatatata
     3241 aatatattta tatacatcat atatacaaaa caattgtttt tttattttat attcattagc
     3301 attgctcata aaatacacca taattccaga aaaaataacc aatcagttag gattacatca
     3361 tctaagcaat atataaacgt cttagtttat aagttttatt ctactcttat ctaaaaccat
     3421 ctttaaagag ttttcaactg tttcaattac atctttataa ctcaagtaca catttgcgta
     3481 gatacaatct tcatataaat tatattcagt tactctacaa tacagcagtt ttcctccatc
     3541 taataaattg ctcaaaatat agttttcttt tcttgggaca tagcctatca catatccagt
     3601 ttcaccaact attttaatag ctttttcatc atatagatta tctttctctc tagttaaata
     3661 gtatatctta cttttctcca attctttttc aagatattct ctatttctaa accttgaacc
     3721 agcaacagct attgaagtca aatagatatc cttaccatgt tcatctactt ttattttttc
     3781 aatatttaca aattcttttt ttaaattatt actttcatat aatactcttc ttaattcatc
     3841 cttcaatata acattttttt ctttttcata cgcttcttta acaattttta attcttcaag
     3901 agatagtttc tctctgtatc tttttaagat atttatggat tcttttctta cttcatttat
     3961 atttccaaat attcctttta aagatatatt ctttccttca ggatatagtg atttacttcc
     4021 tttaagcaca ataaaaaata acatatcatc ataatattct tgagtcaatt tatctttttc
     4081 tatatctttc atttttccaa ttaaatcatc tattttaaac gtctcttcaa aaaaatttaa
     4141 taattttaat ctagaacttg tcgttccctt tttagatata tgccaatata cctcaaaatc
     4201 tctaatatct ctatttagat atggcaacaa gtcatcaaaa gataagttta catcataaat
     4261 ttctgacatt tttataatat cttctgtttt tccactagca tctcttaatg cttcaaaata
     4321 tatatttttc catttttcac tgagcaagat accatttatt tctttttcaa attcaatctt
     4381 attgcactct atattttcat cttttaagac gtttatagct attaggaaaa ttgaatataa
     4441 actttcaaag ttagtcccat aatttactac agtaggtaaa aatcgattca ctaattctaa
     4501 tttattacct atatatttaa attctacact tagcaagtaa ttgcatataa gacgtgctaa
     4561 attatttatc ttttctttat ctaaatctcg tttttcaaga tattcattca aatctacaat
     4621 tgaaataata tagttcatca ataatcgttc gtactttgta tccttataac catcttcaat
     4681 tagataggaa tttattttag aatctaaatt ttccatatta acaatagcaa atacttttat
     4741 tgaacctgta gcctttttag ataaattaaa taaatatgta ttgtaaaatt caagtttttt
     4801 aatagtatta ctcagataaa atacgtattc tccagattta gaaaatgtat ctacaacttc
     4861 tcttaagttt tctacattta gatatttctc acttaaaact aaccctagtt ttacatactc
     4921 aactttttta ctcttatata ttaattcttt agttaattta tataaccatt tctcatcaat
     4981 aatcatttct tttaccaaag tatttatctt tttcataaaa atttcgaaat aacaaattaa
     5041 agacttagaa ttactaccct ccaataaata aatttcatta gattcacttt tatacatatt
     5101 taaaatttca tctactagat tatttgcaag ctctacttgt tctcttaacg gtatactttc
     5161 atatatacat aggtaattca tttcaaatga ttctttgtat ccatcataac cattaaattc
     5221 ctgcaatcgc ttaaaaacat tctccaccaa attatcctcc tttacatgat gtaatttata
     5281 ttgattatac tacttatttc atcaagttta catttatacg caaaaaaata ttactagaaa
     5341 ttgaaattct agtaatatcc ttattattaa ttatgtaaat accctatctt ataactgtaa
     5401 ataatatcct tattaatttt aattactttt aataaaaatc tatcctagat ttagacttct
     5461 ctatgcatat attatactaa tattagacat cataatcata cactttttct ttttcatatc
     5521 tcatgtttac aaacaatgca agtaaaattc caacaaatgt tattgccaca ttaaacaata
     5581 caacatattt tggtccatta actccccctg attttgtaat aatacctgct atatttaaaa
     5641 taacatagtt tgctatacta gatgcaatca taactataga tgttattttt cctttattag
     5701 ttggaaacat ttcatttgca gttgacgttg ttaactgaag aacacctcct gctgctgaat
     5761 aacctattac aaatccccct aacatacaaa tagttggagt ttgaacaaaa tatacaacta
     5821 atagcataag taaagctatt ataggatata taactaatat tcttattggt ttaatatatt
     5881 ttttaataag taaagaagtt attaatactg cacatattac tcccattgag taaaaggatt
     5941 gaatttttgt agggtcagcc atcccataca atttacccaa ttcctgatta caatttaacc
     6001 ataatacaaa tgtagatgta catgtaaatc caatacaaac aagagctata cttgttggtg
     6061 taaatttcat cttctctgat ttaactgttt tgcctttgtt atcaataaca ttattagctg
     6121 gtggaaatgg taacacagct atcaaaaagg catctactac aataagaatc gctgttacta
     6181 taaaaataac tttaaatgat attgaatttg ctgcaacaaa tccaattata aaaggaagca
     6241 aaaattgtgc taaagctatt gtaaatttag taaacatatt tgctattgtt cctaaactag
     6301 caaatatctc catacaagaa ggagttacac aggtatctaa gaatgaattt gctgcccctc
     6361 caattattgc aaatacatat gctatataaa aatttggtga aaatacaatt ccaacaaaga
     6421 aaattgcatg tagaaagttt cctataagac cacttacttt tcttccatac ttatctgaaa
     6481 taggtcctgc aaatggataa gatataagtc tccctaatcc tagtgcagca ataacagcta
     6541 aaacaatact tacatccaat gttccatctg ataatgtttt agccccccac attgatgaaa
     6601 attctggttt gtattgtcct aaaattgaaa ttccaatacc aagtaaaaaa tatgaaaaat
     6661 acaacgctat ggcagtagga taatattttt tattgttcat aatttttctc ccattcttgt
     6721 taatttatta acatttttgt gtacaataaa ctcatcccca taatggattt aaagtatagt
     6781 cagttaaaac ttcaaattta actggactat gaggcaaaac ccactatgac aatttgtaat
     6841 ttattattaa aaatattgaa atacgtatgt tttttcattg tttaagatat tactcttatc
     6901 tatttaaagc ataattcatt aacttcttct acaggcattt ctaatccagt atatagatta
     6961 aaagcttctg ctccttggta taataacatt cctaatccac caatagcctt acatccatta
     7021 gcttcagcat cttcaatcat ttttgttttc ttaggattat aaacgacatc tgttactact
     7081 aaatcttttc ttaaaacact agtatctttt atatttgttt cattgtcata aggcttcata
     7141 ccaataagag ttgcatttgt caatatatca cttgattgta tctcctcata aagtttgttt
     7201 gtatcttcta aatcatatag attaacaaca cattctggta catctttttt tatattctca
     7261 actgtttgct ctgctctttt ataaaaatca tccttaggat taaagataga tatttctctt
     7321 gctccatcta aagcacattg tacttgtata gcagttgctg caccaccagc acccataatt
     7381 gtaatctttt tacctttaac ttctacccca ttttctttta aattacgaac atagcctact
     7441 ccatctgtta tatgaccaac taactttcca ttgtcattta caattgtatt acatgctcca
     7501 attatacgag ctgctggaga aagttcatcc atatattctg taacagcaga tttacatggc
     7561 atagtaacat tggctccttt tatattaaaa gtttttattg ctaaaagtgc ctcttttacc
     7621 ttatctactg tgatatcaaa ggctaaatat ctataatcta aatctaattt cttaaaacta
     7681 taattataca tcactggtga tttagagtga ccaaccggtg tacctattaa tgcaaataat
     7741 cctgttctac ctgaaatttc cataactata atctcctctc aatattatca ttttctttgc
     7801 aaataaccta ttcagttatt tacaaagaaa aatttattta ttatttatat atttaatgct
     7861 acttcaaaag cttcttttgt tgcatctaat gccctacgag cttttactgc atcaccaaca
     7921 atataagttt cttttacaac ttcttttata acttcactta atgggtcgta attacgagaa
     7981 cccatagcaa gtactactga atcaaaacct tttaaatcat gctctgtgcc atctgtaagt
     8041 aaatagtcga caccatcatc ataaaattta gaaacttttg caccagtaat ggtatgtata
     8101 ttataatttt caaaatcatt cataaggaat ttacggtgtt ctgaaattac atctgcacca
     8161 acttcttctc taagctcaat aacagtaacc tcatgttctt gttctccaag gaaggctgcc
     8221 acttcacatc caaccattcc acctccaaca acaagtactt ttttcccaca agatttttta
     8281 ccatcaagaa ggtctacagc atgaattaat cctgaatcat tgattcctgg tataggaagt
     8341 acaagtggag ttgctccagt agctataata actacatcag gtgatttctc ctttataagt
     8401 tctactgtag cttctgtatt agtacatatt tttacaccat attgattaca ttttgaaata
     8461 taacttctaa ctaagttagt aatatctcct ttccctggag gatatgcagc taaacgcatt
     8521 tgcccaccaa gaacttcaga tttttcaact aaagttacat tatgtcctct tttagcacat
     8581 acccatgctg caagcatacc tccaacacct ccaccaacaa caagaacttc tttgctaatt
     8641 tcagctggct taagctctgc ttcatgtcct aatataggat ttgcaagaca ggctataggt
     8701 ttgccttgga acatatttgg tacacatcct tgtaagcatg caatacatgg tatcatttcg
     8761 tctagttttc catttttagc tttattaggc atttctgggt cagccaagct ttgtctaccg
     8821 aatgctacta aatcacatct tccttgtctg accattaact cagcaaactg tggctctgta
     8881 taacgtccaa ctgttattac tggtatacta acagcttttt ttatttcagt aactaattct
     8941 gcactgaatc cagcatgtaa agtcgtagga gcccacatat attcatcatg tatatgtata
     9001 ctacgtgaaa catgaagtcc atctattcca caatcttcta gatatgctgc tattactgaa
     9061 ctatcgtgta catcaattcc tcctggaaca tcatcagtgc tgtttatacg acataatatt
     9121 gctagagaat ttcctacttt tttacgtata ttttcaatga taagacgagg taatctcatt
     9181 ctattttcaa aacatccacc aaactcatct acacgcttat ttgttctttg tgatataaaa
     9241 ctactaacca gatatccatg agcgcagtga acttcaacag catctgcacc agctttttgt
     9301 gcacgtaatg cagcatctcc ataagattct ataagttcat atatttcttc tgttgttatt
     9361 gctagtggtg tattacgacc atttgatgca ggtattgcag aagcagcttt taatggatgt
     9421 cctgctactt tttcatttcc ttcagaacca gcatgttgta attgtataga taccttcgaa
     9481 cctgcatcat gacaagcatc tattacattt ttaaaactat ctattgtgct atcatcatat
     9541 aaacaaggct tacgaggacc tccttttgct tttttgtcta caacactaga ttctatagtt
     9601 attaatccaa aaccacctaa agcacgctca agataataag ccttagaagt ttcacttaaa
     9661 gtaccatctg tgtttgcaaa attgtttccc atagggggaa ctacaaaacg atttggaact
     9721 gtcattgaac caattcttat aggtgtaaac atagaactaa tcttcataag gttttccttc
     9781 ctttcaagtt ttatattata atactctgta tatttttata ttatataagt ttattttgga
     9841 gatacttcag accatgcttt atccaaaact tttttagttg cattaaatac agtttcagca
     9901 gcagtggata accctttaga tattagagaa tcagatatta cttctgcccc tatgactctt
     9961 ggtgatatat tgtgttcttt tattattttc acaaattcct ctgtgtttcc atatccttca
    10021 cctggagcca aacggtcatg tagtgattca tccctaagtt tttcataagg agtttctaaa
    10081 acatcacaca cttgaattga tactatctta tctgctggaa caggtgcaag gtcctctgct
    10141 gtctgctttg ctctagccca gtgccaagta tctaatataa gcattgcatt ttcacgatta
    10201 catcctttca caacacgcca tgcagtagcc aaatctggta caccactata tggcataaac
    10261 tcaagaccta taataagttc acctgctctg tcacataatt ctcccaatgc agttataatt
    10321 tgttcttctg gtatcatctc taataatcca caatttatat gtttaacatt aaataagtga
    10381 gccatatgat aaacattttg ctctttttct ctttgagctt ccgttctatc ttcttctctt
    10441 ccccattgag ttatatattc tacttctgta actttcatat catattcatt aagaattgca
    10501 atcatttctt catctgtaac acctgcattt tttgcatcaa tataattttc agcacgcaat
    10561 ccaataccat caaacccagc ttcttttgca atacgaactc tatcacggaa tgaaacttct
    10621 gttcccaatg tataagaact aattgtaatt ggaatattaa gatttttttg attattcata
    10681 gcttaaattt gcccccttta ttttctttat aattaatagt atttttgatt ttatattttt
    10741 atttatccta ctagtagtat tattttacct taaaaataaa agtatttttt gatttctatt
    10801 tatctagatt ttataaattt attgtatcac gagactttac taataacaaa ttgataattt
    10861 cctattaatt catagatttt gtttatagat tttatttata agataattct tgtatttttc
    10921 tattaggtcg tataaatata tttatcttat aattcagaca aaaaacgata aattttttta
    10981 aaagctttta ttcttactct ataatcatat ataataaaaa tgtaaaaata tcttaaaggt
    11041 taacttctac aaatatataa ataaaaatac ctatgaaagg atgaacaaaa attgaattta
    11101 tatcacttac gctattttgt tacattggca catttagaac actatacaaa agcggcagaa
    11161 aatttatcta taacacaacc aagcttaagt catgctattt ctttactaga aaatgaactt
    11221 ggggtggctc tatttgaaaa agaaggtaga aatatagtcc ttactaagta tggaaaaata
    11281 tttttaaaag atgtggaaaa atcattagaa attttagatt caagtgtaaa atcattaaaa
    11341 ataactggta ctggtgaagg acaaatagac ttagcttttc ttagaacact tggtactgat
    11401 tttatcccag acatagtgca caaattttta aaatctaatc ctgctaaatc aatagatttt
    11461 aaatttcata ctggtgtaac tactgacatt attcaaggtc ttaaagaaag aaaatatgat
    11521 attgcatttt gttcgaaact tgaaaaagaa aagggaattg aatttatacc tgttgccaaa
    11581 caagatttag tactaattgt accatatagt catccactag ctgcaaagga tactatagat
    11641 ttaaaagaaa ccatacctta tcctcaaata gtatttaatc agagaagtgg tcttagatat
    11701 ataattgatg atatgtttaa aaaaataaat caacagccta atatagtcta tgaagtagag
    11761 gaagaccaag taattgctgg attagttgca aaaaatttcg gaattgctgt agtcccaaat
    11821 atgaatatgc ttagctttac aaaagtaaaa gtaattcaga ttattcaccc aagttgggaa
    11881 agaaactttt acttagcatt tataaaagat agatatttgc ctcctgcaat taaaaacttt
    11941 aaaaactttg tcattaaaaa cgctcaatta taatttatta ataaaggggt tatttttaaa
    12001 tatcctcttt tattcttttt ataaaataaa aaaatctata cttttaaaag tatagattcc
    12061 taactgacag tcggcatccg agtctcagta attatcgtta tacaacagca actggattca
    12121 gttcctgaat aactaggtta cttacattat atcagatttt ttaaaatttg tcaattgtat
    12181 ctaacgcatt ttttcaagcc atggtccaac aggctctaca ataggaactt ctttaaatcc
    12241 ccaatttctt atatcattca cactcgttgg agtatatatt ttgtttctga cagatttgaa
    12301 tattttgttt ttttctccat attgcataca ctttggatta gcttctatta accctcttct
    12361 tgctctgcta agaggattac ataaaatatc tgctatttct aaaccttctc tatagtcagc
    12421 atcttctttt ttggcaatta taaaaccctt aaccttatct cttaattctt catctatatc
    12481 taagtatatt gttccattat taaatacatc aaaaaacgcc ttttgtactt ttaagtttga
    12541 gacatcatcc cttgactcta taactattcg tgcagattct acagtttcat tatttacaaa
    12601 tgaataaaaa ttctgaagaa catgtataaa agccacaaca tacggttcct ttgaaggtgc
    12661 ataatatttc tttaatctag ctttatctac tgttactgat attatagtac actctaatct
    12721 agatagaaat aaaggcaact catcatagaa taacttaatc tgtgaatcat caaacttctc
    12781 aaatgctctt gattttcttg atatatctgt caaatgtatt cctatgttac tggttccaaa
    12841 acaatactct ttaaatgcat ccatttcttt cctcaaagaa catacataat cgccttgact
    12901 tactgcatat ttatattcaa aaattactcc tgtcaatgta aatgggtctt catgatttat
    12961 atcagctctt ccactttcat caataaacat tatatatttt ttctttataa tcttactcac
    13021 cctcttaaca tatgatgata gcatctatat tcattttata tgagttttaa aaatattcca
    13081 agatttttat ataacttaaa cttaatttta tactaaaaaa ttgagatgta aaacaatcaa
    13141 gcttttattg attgaatttc acatctcaat tataattatt tttcaatata tatttttact
    13201 attttgcaag aatatccatt aatttatcca ttactatata agatactccg cctcctattt
    13261 gataaggagt ttcaactttt ttatttgcaa atactctttg ttgctctgat gataatcctg
    13321 aattatccat taaaactatt ggtgaatgta attttacagc taatggtcca gctgataaag
    13381 catctactaa agcatctgat ttactaacta atacagcctg taaatcagta tctccataga
    13441 atttttctat cactttggca ttagtatcta ctctactatc tccatatatt ctatttcctg
    13501 aaatatcttc agtagttata tcattcattt ttgctattac tgaatcgtta attgcacttg
    13561 gtccacctat aaagtatgca ttttctaatt ttctttctgt tagccattta taagattctt
    13621 ctgtaattcc atctttattg actaatatta taggttgttt ttcttcccca gctttagaag
    13681 ctacagataa agcatctgcc tccccatttc cagaaaccat atatgcagtt tttatttctt
    13741 ctcgatttcc aagttcttca gctattcttg tagcagtttg atatctatct tgacctgcta
    13801 ttctctttgt ttctgtgttg aaagtagttt ttatttcttg ctctaattta gaacttattg
    13861 cattttctcc acctatcaag attactgttt taggtgctaa taacttcatt tcttcaacag
    13921 tttcagttgg taaattagct gtattagtaa gtagtattgt tgagtcatag ctacttgcta
    13981 aaggagttgc tgttatacca tcagctattg cattaccatt tactaatatt acagtatctg
    14041 aactatcagc attccagttt ccaactgaac ttatcttttt agctgtatca aatctatttg
    14101 cacctataat tgtatcccat gtaggattta tagttccatc ttcattaaaa gtataatctt
    14161 tcccatctat tttttgagaa ccagttagca tctttccatc tttgtctaaa tagtaagact
    14221 taccatctat ttgttgccat cctgtctgca ttattcctgt tttgtcaaag taatacttat
    14281 taccatctat ttcttgccat cctgttactg ctaaaccatc agatcctaga tagtatttct
    14341 ttccattctt ttcttgccat cctgtttgca ttactccatc tgagttaaag taataagttt
    14401 ttccgtctat tactttccat ccagatactc ttgctccatc agttcctaaa taatattttt
    14461 tgttattaat tgttttccat cctgtttgca ttactcctga agcatcaaag taatacattt
    14521 ttccatttac ttttagccaa ctattctttt ggtatgttcc atcagatttt acataatact
    14581 tcttaccatt ttctgttttc catcctgttt gatttagatt tatcttatat tttgccgcta
    14641 tctttacata gctgtcgtta ctataatcta taattacatc tgaacctaca ggaacttggt
    14701 caaataacca tctaacatct ttattgtgca ttcttataca tccaccagaa atatgctttc
    14761 ctatagaact ctcattatta tttccatgta ttccatatgt atctccataa gttcctttta
    14821 atgctaatcc catccatcta tctcctaatg gatttcttgg acttcctcca ggtatattac
    14881 ctttataata tggtctattt tttatcttgt taactacttt tgttttccct gttggtgttt
    14941 ctgacccctt tttacctgtt gcaactctaa attcttttac aagtttatta tttacaaaat
    15001 atcctagagt attttttctt gaatttacta taatcacatg tttactggct gcgcttgatt
    15061 ctggtacgcc acatgcaaat actaaaacta aagtcagtgc tagtactaaa tactttttta
    15121 gacttttttt cactataact tccccctctt ttagaaacat tactacatgt gtctaattat
    15181 aacataaaat taccaatacc ttatatttac aaatttgtta catttataca tataagtatg
    15241 tattctactc ttcataccca ttaggattca tactttgcca tctccatgaa tcttcacaca
    15301 tctcttcaag ttcatactta gctttccatc caagctcttt ttctgccttt gaagaatctg
    15361 cataacacat ggctacatct ccagcccttc ttcctacaat cttatatggt atttcttttc
    15421 cacttgcttt agaaaatgct tttactaaat caagaacact ataccccttt ccagttccta
    15481 aattataaac aacaagtcct ggattttctt ctaatttttg taatgctttt acatgaccag
    15541 cagctaaatc taatacatgt atatagtctc taactccagt tccatcatgt gttggatagt
    15601 cattaccata aacactcaat tccttcaatt tacctactgc tatttttgtt atataaggca
    15661 ttagattgct cggaactcca tttggttctt cacctattct accactttta tgagcaccga
    15721 ctggattaaa gtatcttaaa agagctatat ccaatgactt atctgctttt gatatatcta
    15781 ctaacatctg ctctatcata agtttagttc ttccatatgg attggttaca gaaagtggaa
    15841 aatcctctaa tataggacaa gtatgtgggt ctccatatac agtagctgaa gaactaaata
    15901 caaacttttt aacaccatat tctctcatta attcaaataa atttaaggta cttattagat
    15961 tattgctgta atattcaatt ggtttttcta ctgattcacc aactgctttt aaagctgcaa
    16021 agtgtataat tgattcaata ttattttctt taaatacaac atgcatttca tctttatttc
    16081 tgatatcaat attataaaat tttactggtt ttttagataa ttccttgatt ctatcaacca
    16141 ctattgagtt gctattactt aagttatcaa ctataacaac ttcataacct gattctaaaa
    16201 gttctattgc tgtatggctt cctatatatc ctgctcctcc agctactaaa actgccattg
    16261 taattacctc ttttctaata tttatttttc acttactttt tttctcatat agtccattaa
    16321 atcatctttt aaattttctc tctttagagc aaagtctatt gttgcctcta aaaaaccaat
    16381 tttatctccc acatcatatc ttctaccttc aaagttataa gcataaatag cctcttgttt
    16441 tccaagagtt tgaagtgcat ctgtcagttg tatctctcca cctttaccag gtgtctgttt
    16501 ctctaatatg ctaaatattg caggagttat tatatatctt ccaagtatag ctatatcaga
    16561 tggagcttct tcaattgcag gtttttcaac catatcttta actttatata ctctatcttc
    16621 gatatgtttt acatccaata taccatattt attagtatct tctttagcta tcttttgaac
    16681 acctaataca gttgttttat actcattata agtatctatt aattgtttta agcacggaac
    16741 atctgaatct actatatcat cacctaataa tacggcaaaa ggttcatcac ctataaaact
    16801 ttttgcacag taaattgcat gtccaagacc ttttggctct ttttgtctta tataatgaat
    16861 atttaccata tttgatatgt ctcttaccat ttctaacatc tctgtcttac ctttttgctc
    16921 tagttctaac tctaattcaa ctgatttatc aaaatgatct tctatagatt ttttatttct
    16981 acctgttatt ataagaattt cttcaattcc cgattctata gcttcttcta ttatatactg
    17041 taaagttggt ttatctacta taggaagcat ttctttgggc tgtgattttg ttgctggtaa
    17101 aaatctagtt cctagccctg ctgctggtat tattgctttt ttaactgtca tctgcatttt
    17161 ttcacccttc ttcgtaaatt ttctattgta ccaaattaat ataccatatt tatacttttt
    17221 cttcaaactc tatattatcc caatatttaa tgctataaga taatataagg tagatgaaat
    17281 ttcatctacc tttagtttta taagttaata ttgtattgtt tatattttat ccaaaactta
    17341 tacaggtact aaatttcatc taagatgcct tttatatcac tatctatatc ttcatctaga
    17401 taagaatcta aatcttctaa gtcaacttct agttcttgat atgtcatatc aacactgaca
    17461 tcctcatcta tatccatttc tgatattaat tctcctaaaa tactatttcc atcagaatct
    17521 aaaccactat ctatatcttc atctatatag ttttcattta aaatttcatc taaatcaatc
    17581 tcgtaataaa cttcattatt tttttcatcc cctgagtcca atcctaagaa ctcatagtta
    17641 aaagtccaaa cattgtattt acttgacata ctttattcct cctgtgaaaa acatattttc
    17701 atctagttta ttggttccat aatcaacaga gttatatatt ttttcaatta tgtcttttct
    17761 tctttctttt gtactattat ttaatgtcaa ttgtttaaat acatatgtat ttgttattct
    17821 ctcgaataat atttctttta tactatcatc atcaatattt ctatagtttt tccacaataa
    17881 ctcaaataac ttaaacattt ccctactagt ttcatctaca taataaggat acatattttc
    17941 tactaaatgg tttaatcttg atatggcttg ttttaaaaat acatcaagac ttgcactttc
    18001 actttctttt aacattctat aattgtattt cttcttatct tctcctgaaa ttacaaagat
    18061 gatattgtct aaactttttt caacttcatt taaataactg cttatattat atgataaatc
    18121 agacaataga tttttaatct gcttaaacac ttgtacatca agtttagtat tatacttttc
    18181 aaacaaatct atttcttgat tttctaatat tcttggcata tatgctgaca ataaatctaa
    18241 attgtttctt tgttcttgta tttgcttata aagtgaattt ataacttcta ttcttatttc
    18301 atcatttaac tctttttcta aaatcttatc aaattcagat ttcatatagt aaatatttcc
    18361 aaagaaatta aatattatca tatcattcat agctttagac caattcttat atatcacttc
    18421 aatagaattt tctttaagta gaggttgctt tgcatatata aatacatctt gcataagttt
    18481 ttgaaccata cttttactta agtttaaaag tactttttga ttattaaatt ttatttccgt
    18541 ttctacaaaa ttagaatttt cgttttcaag ttctttatta attacaatgt cttttatatc
    18601 actatttttt atagatatga tttctttttg aaaagacttt agaatagtca agctatcgaa
    18661 atcttcttga ataaaaaatg gagcatgttt taatgtatat cccactattt cattttctat
    18721 atcttttagg tcatctattt gcataatttc tctattttta tcatttatat gtaggttaaa
    18781 tacattttta ttatcatata atattatatc ttctcctaaa tttaacttag aacaattatc
    18841 tttcgctgac tttacaatag tcttcttaga tttcttattt ataaaaatta attggtcttg
    18901 atattttact aaaagcatgt ttgtgttttt ataatcaaat ccatctatat ttcctgatat
    18961 cttgcagaat actatttcac aatctttagg aagatttcct attttttggt tatctttaac
    19021 tctctcattt aaatcagatg ggactacact atctatattg ttattaaata tagatacaga
    19081 ccttactata atcccctctc tttccatatg aaagtatccc ttcaatgaca ctcttttatc
    19141 ttctaaaatg tatctttcta tatcatcaaa atttatttca aatctatttt tcccactgat
    19201 aaatataaac ttctcattat ctttattaat tccacccata taaaacttat tgtcatctaa
    19261 acttaatata gtcatattat cctttagata gaatataaat tctctttgac ttttgcagat
    19321 taaatcatat tcatccaaag ttattttcat agtcaaattt gctgtaacat ttttacttga
    19381 attttcactt tttatgtaaa aaggcaagtt atttccatag acaattattt gagaatcttc
    19441 taaaactgcc tctaattttt ctttattgtc tgaaaaacta tatatatatt ttacacctgt
    19501 atcctcatta acttcatctg atttgctgat tattatattc cctagatttg ttatatgaag
    19561 ctttttatat tcttttgagt atctacttat gccactaagc tcaaacccat ctgaaagctc
    19621 atatatgatt ttttctccta atttcaacat accttcacca cctaaacaga attataagta
    19681 ttttataaag gtgaataaaa tgtctcaaaa caaataatat tttttttaat actttttatt
    19741 ctgagacata gtttctcctt ttttataatg ctctaagcac cttcaactat ttcttcataa
    19801 agtttatcta aatgtttaac atattcacga tatccagatt tgttctttaa ctcacttctt
    19861 aaatcttcat atttttgttt aagttcttca gcactcaaag aaggagctga ttcttttaat
    19921 tcttctaact tataatcata gtacttatca tacatagcta tatatgtatc aatagacttc
    19981 ttagctagtt cattacattt ttcttgtgct tctccatatt gagaataatc acctattttt
    20041 attttatagt atccattttc ttgaattatt gttgaagaaa tacctttagc ttcatattct
    20101 tttgctgttt cttttgctgt tttttcaact ttaagtgaac ctgcataaac agtgtaatat
    20161 acacctttac catctttata tgcttccatt tcttttgctt tcttttcagc ttgtgctttt
    20221 tcttgagcct ctttttcagc ttttgccttt tcttctgctt cttttttctc tttttcagct
    20281 tgtgcttttt tctcttcttc agttaattta ttgttagctt gttgttgagt tgatgacttt
    20341 ggaatattct ctttatcatt tttcttattg ttgcctactg ttataaaata tcctacacca
    20401 acaataacca ctataactac tgctataata gtttctttta atctactctt cttagaaaca
    20461 acctcttcat catctaaaga atcttcttta tctgatacat aatttttcat ttctttcttg
    20521 ttttctctat atttgtcctt agaagaattt ttagattttt tattactatt ttctttcttt
    20581 ttaataggta ttactactga tttttcattt tctaattttt cttcttttat ttcttttgct
    20641 tttttatctt ctaagttttt actttctttt tcaagcttcg attcattatt tgaagatact
    20701 ttttcatcta agttattatt tattggtttt tctattttta cactacgttc ttcttctata
    20761 tgttgacttg gttcttcttg ttttatttct ttcaattcat tttgctctat ttcttctgat
    20821 ttcacttgat gattttcaac tggtttatct aaaattatat ctggagaaat atcatttaaa
    20881 ttctcttctt cttgttcagc ttcttcattg tcttttttaa taaatccaaa taatttagcc
    20941 ttctttttac tctttttatt ttctggttca attatatctt ctttattgct gtcgtactct
    21001 ttatctgtag tatctttatc ttctacaacg tcacctatat cttgattatt actatctact
    21061 tcttctttag tcccttcttc agcatcatct tctattgaaa tactacttct aaagcaaata
    21121 tctttatctg cattttttat catgtaaatg tattcttcaa tatcgatatc tttatttctt
    21181 ctagttcttt ttgatgcaat ttcatgattt tctaattcac tatagttatc ttttattaga
    21241 ttctgtgctt tattccatgt atcttcacta atttctgttt tatttttaat tacatagtcc
    21301 acaaattcct taaaattttc aggaccaaat tctccaatta tagtcagtct cattgcacct
    21361 tctataaggt ctctatttct tctctttaaa aattctaata caactgttgc acaagcaaaa
    21421 tctttaataa tttctttgcc aaaaccatat gcttcaacag aatgaagttc ttctaatcca
    21481 cataacttct tatattcatt gtgtattgtt tgagatatac tttcattatt taagctattt
    21541 aacttatcta taaacttcga ttctatatca tttgattttg attcatgttt tacttttgaa
    21601 tttttaattt catttagtag catgtcattt tctgaattat ctttacctaa ttgcaaatcc
    21661 tcaatttcag ttgcttttat ttctactttg ttttgttcgt tattctcttc cacattatta
    21721 ggtaccacat ctttattact agctaatatt ttgtttacac agaatataat ttctcttttt
    21781 aattctcttt tcgcatctgc ttgattttta agaaataaat ctccacattc tttcttttct
    21841 aaacttattt ttctaagaga tatattaaga aggtctttat ataggtttaa aaccttataa
    21901 tccttttcta aacgtcttct tctctctgat agttccattt tatcataagc taaaaaacta
    21961 tttaaatcat tggcttttag agagtctaat ccctctttca tagccttatt tacatacttt
    22021 ctacattttg ctgtagttaa ctctaaatct ttttctaatt catctatttc aggtatgtac
    22081 ttatctacta tccatttgcc aataagtggt tctgtatttc ttgctaatgt cttataaaac
    22141 aatatattaa attttaaaag ctctgcatat tttgcttcat taaattctac tttttcaaat
    22201 ttcttttcca aaacaccatc tagcttttca tttattttag actcttgttt taaaaaactt
    22261 gctgtgacat ttaaaacagt gtttcttatt atattatttt cactcaaaac cttcactcct
    22321 taaatcaatt attttattgt aatatttaca ttgtgcaaag ttgctaattt gattatgata
    22381 tctaaataat tatttactaa atttgctaca tcttatatca tatcatatta tttacatcat
    22441 tttacttttt ctttttatat ctatcttata ttataccatt tttaatatct gtactaactt
    22501 atattacaat attcctcaaa attttaaaag tagattagac aaatttacaa ataaaaaaac
    22561 atcagtttaa actgatgttt ttgactatcg aaataattaa gcaagtctat aagcggagtt
    22621 ctgtattaga taatcatctt tctaggccta ttgtcaccaa taggctcaag cgacctacct
    22681 accggagagt acgagcagca ctctttattc ctatcttggt cttgctccag gtggggttta
    22741 catagccaac tagtcgccta gctgctggtg agctcttacc tcgcctttcc atccttacca
    22801 caatagtggc ggtttatttc tgttgcacta tccttaggat cgctcccact aggcgttacc
    22861 tagcaccctg ctctatggag ctccgacttt cctcatgtaa gattacatgc gattatctgg
    22921 cttacttaat atttatttta cttagttatg ttaacacaaa ttcttttaca tgtcaaagta
    22981 atattatact aaaaatttaa atttattcaa aaatagtgta atatagatat ataaactaca
    23041 tttaactcga ggtgatctat tgaaaaaatt atatagaata gtaattaaca ttatactagt
    23101 attagtaata ctttacagtg gatttaatat atactcaaaa cttaccaaat acaatcatga
    23161 tactaaaata tcctcagaac ttcaaaaaaa agaatataaa aaagaggatt tatcaaagat
    23221 taacagtgat tttaaatttt ggctttctgt tgagaataca aatataaatt atccagttgt
    23281 acaatctaaa gataattctt actatcttga caaagatttt tataaaaaag attctatttc
    23341 tggtacactg tttatggatt atagaaataa atctattgat gacaaaaata tcataatata
    23401 tggacataat atgaaaaata aaactatgtt caacaaccta aataagttta aagatgctga
    23461 cttctttaaa aaaaataata aaataaaaat aaccttgaat ggaaaagaat ttttatatga
    23521 tgttttttct gcttatattg tagaatctga ttatgattat ctaaaaacaa attttaacaa
    23581 tgaatctgat tatcaaaatt acataaatga tattacttct aaatcattgt ataaatctcc
    23641 tattaaggta aatagcaatg ataaaatagt tacactttct acatgtacct atgaatttga
    23701 tgatgccaga atggtgattc atggtagatt gatttaaaac tcacagacac agtttaaaac
    23761 aataatttta aactgtgtca tcttttatac ctataatttg taaattagac cactaaaagt
    23821 atttaataca aaataacaaa tacatcaaac aataaaaaac aataaaaaaa gactatgcta
    23881 aaaacatagt ctttactgga gctggtgata ggaatcgaac ctacaacctg ctgattacaa
    23941 gtcagctgct ctaccgttga gccacaccag cacacctatt ttattgtaaa ttagcaaaac
    24001 taatttttaa aagtta
//
LOCUS       DAEPKC010000058        23434 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.058, whole genome shotgun sequence.
ACCESSION   DAEPKC010000058 DAEPKC010000000
VERSION     DAEPKC010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 23434)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23434)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23434
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.058"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            351..2216
                     /locus_tag="KR294_002333"
     CDS             351..2216
                     /locus_tag="KR294_002333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HBH0240405.1"
                     /translation="MNIPKKIISLLTITIMLSGLSLNTVNASTKESLVGSGRWETAIQ
                     ISKNGWENSKEAVLVNDSSIADALSATPFAKAKNAPILLTQSNSLDARTKAELKRLNV
                     SKVYLIGGNVTLSSNLEYELKSININSERISGDSRYSTSLELAKKIDSINTISKIVVV
                     NGQKGLADAVSVGAAAAQGNMPIILSDTTNGTSTSKDFISKHNITTSYVIGGTNSVSE
                     DIKNSLPNAKRISGENRNQTNAKVVEEFYKGTNLKNLYITKDGMKKQGDLIDSLAVGV
                     LAAKNSSPVLLAGNKLDSVQKDILDTKIFDKITQVGGNGNEDVFKSIQDIQEETKYTV
                     ETISELDTAIKKSDANDIIRFKNDDKITGSIDISTKKAITIEFNGLYSGKVNINIPNG
                     DVYNYGDMTGQMDIKDIKTDTLVNEGSINEITIYDPNGCKIENEKDADIWKITLLDTS
                     KNTYINNSGTITKIVSDASNTTIKNSGKIELISGTKSPAVSGNQATDENIKDNDDKEA
                     GGISVYVDPCSPPKEGKVMLRIPKEPRSSSYNIYYRIVKSRPSAMDVGDTISKRGWTK
                     VTTRDSFMISATDGYYVEAVEIYDSDRKVSKWGRSGSIDDGYNNTTSSATLRSYK"
     gene            2525..2983
                     /locus_tag="KR294_002334"
     CDS             2525..2983
                     /locus_tag="KR294_002334"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240406.1"
                     /translation="MNITNKCVLGISILAILSFGFSAFQGNAQITDRKKDYDIYLKAN
                     SDKSDVKSSLNDISKLEKKYGESDALSISKINLYEKMNDYKNLQSEIEKVYNRYPQTR
                     NTVSFVLLYSEVALKNGNKELSKNMINEAIKLGAQDAYKERVDKVLSQLN"
     gene            2996..4603
                     /locus_tag="KR294_002335"
     CDS             2996..4603
                     /locus_tag="KR294_002335"
                     /inference="COORDINATES: protein motif:HMM:NF016800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HBH0240407.1"
                     /translation="MLDKYYNRGKVEQIDKFILFILLFMMCIIPIITHEYTSTNYSPI
                     FTLTLYSSGERVEIFNFYKTAILYLGTMIVFCFFMYKIFVLKEELKKRKVNIILLILA
                     IGVILSSVFSDYKDIALFGNPDRFEGALAWFCYIVIFFVLYNIKIDVKDLKLFYFGLF
                     PFLVINLFLGLAQFFEIDVLQSKILTTLIGGGTLSGTFWTTLYHFNIMSGIASVIFCA
                     SLVYMLFEKDIKKKIVPLFGAIMSFTIILISNSISGFLTSILLFPIILVLSWRFVNKK
                     ELCVWTIIMVIISSIIYIILNRHNPNVYQETFAMFEKLNQASIFIVPILIVTFILLII
                     IMKFINKKKFFNFVTVCSIVIVSAGLLFFSYTLNKEVSILESNPNANITRIEDSKLFN
                     IINGMSTDRLNIWTKVMNFINERPILGNGFDTFPYKFISTDKNGALSTYGEVIDKPHS
                     WYMSVAYGSGIIGIIGLVGIIIYLTKEVFYSCVDKNNDKFLYIFFIGFLAYSIQGLFN
                     DSLAGSSIISWVFAGLTANRIFTIKSK"
     gene            4802..5761
                     /locus_tag="KR294_002336"
     CDS             4802..5761
                     /locus_tag="KR294_002336"
                     /inference="COORDINATES: protein motif:HMM:NF025025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBH0240408.1"
                     /translation="MNVSIIIPTKNAEKYIENLIKALINQTIEPCEIIVIDTESKDKT
                     VEICMEYDIVKFIQIKQSEFGHGSTRNRAAKLSKGDILVFMTQDALPQNCYFIEELIK
                     PLGKNNIVCTYGRQLPRNNAKTLEVFSRSFNYGNSDIIKSKEDIPKLGVKTFFFSNVC
                     SSFIKRDFFLVDGFPENIIMNEDMIISSKIIYNGKKTCYASKAIVTHSHRYTYLQQFK
                     RNFDIGVAFKENSYYLSEVKSESEGFKFVIEAIKFLFQSNKCYLIPSLFIESGFKFFG
                     YKFGMNYKNMPIKLVKLMSMHSFYFDRKEVMEEYYSENSNNRC"
     gene            5736..6587
                     /gene="rfbD"
                     /locus_tag="KR294_002337"
     CDS             5736..6587
                     /gene="rfbD"
                     /locus_tag="KR294_002337"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HBH0240409.1"
                     /translation="MKIVITGAKGQLGLEIVNQLDNLNNIREKNIYDIVPTDRSNLNI
                     TDLENVNNFIFKEMPDVVINCAAYTKVDLCENDIDNAYKVNALGVRNLATACEKIKAK
                     FVQISTDYVFDGNSNIPYKEDCITFPNSIYGKSKLMGEYFTRQFSSKYFIIRTAWLYG
                     DGDNFVRTMLNLAKNNNEINVVYDQIGSPTSTVELAEAIINLIETDYYGIYHGTCEGE
                     CSWYEFANKIFELSKITVKVNPITSNEFKREAPRPMYSVLDNFMLKLIGLNNFNRWDE
                     ALKKYLE"
     gene            6615..7493
                     /gene="rfbA"
                     /locus_tag="KR294_002338"
     CDS             6615..7493
                     /gene="rfbA"
                     /locus_tag="KR294_002338"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007060455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HBH0240410.1"
                     /translation="MKGIVLAGGSGTRLYPITKCVSKQVLPIYDKPMIYYPISVLMLS
                     GIRDILIISTVRDIKIFKELFGDGSQLGVNIQYAIQEKPNGIAEAFIIGEDFIGDDKV
                     ALVLGDNIFYGYGFSERLERAINRDEATIFGYHVSDPTSFGVVEFDKDFNVLSIEEKP
                     KIPKSNYAVPGLYFYDNEVIKIAKSIKPSKRGELEITSVNNEYLKKGKLKVELFGRGM
                     AWLDTGTHRGLLDASNYVEVVQTRQGLYIACLEEIAYIKGYITKEDLLELAKPLMKTD
                     YGKYLIKIANEFKENK"
     gene            7701..8597
                     /locus_tag="KR294_002339"
     CDS             7701..8597
                     /locus_tag="KR294_002339"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240411.1"
                     /translation="MNSWRDTLYTPTSIEKIDDLYFIVDCWQHRVIYNDNLSDKISNW
                     KTLSDNLEGPHSIASDKEVFLVDNTEKNEIQVFKRKEDNFILTQTIQNVGKRPHKIIY
                     DKNTNLFYSIASTSQDIVVLENINGNVRVKQKTRLDFLDGSYIRSISIIEDKMYFLPG
                     PNKVICTDYKSGKFNVISEYKLPKALEAINHLYKIDNYYYISLYTMGENPNEPKLVRF
                     KNFNELQNNEYEDLTKKLNIKGVPYFFSEFDGKVFFTEIDSYSEIKSFKVNNDNIDSI
                     VNYYDSGKPSKESIERKKSILR"
     gene            8641..9213
                     /gene="rfbC"
                     /locus_tag="KR294_002340"
     CDS             8641..9213
                     /gene="rfbC"
                     /locus_tag="KR294_002340"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003467069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HBH0240412.1"
                     /translation="MSKFNFIETKLKDLYIIEPTIFGDSRGYFMETYNKREFLEAGLD
                     MEFVQENESKSKKGVLRGLHFQTENVQGKLVRVAFGEVYDVAVDLRIGSPTYGLWEGV
                     ILSSENKRQFYVPEGFAHGFLVLSNEAVFNYMCTNYYNADYEGGILWNDKDINIEWPL
                     DKVDSVILSEKDKKLLKLSELDLQFKYGGE"
     gene            9217..10239
                     /gene="rfbB"
                     /locus_tag="KR294_002341"
     CDS             9217..10239
                     /gene="rfbB"
                     /locus_tag="KR294_002341"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HBH0240413.1"
                     /translation="MSKVLITGGAGFIGGNFVHYILDKYPKYEVVNLDLLTYAGNLET
                     LENIKHKHNYKFVKGDISNRNFIFDLFDEERFDIVINFAAESHVDRSIKEPWKFINTN
                     VIGTQVLLDASNKYGVNRFHQISTDEVYGDLPLDRLDLLFTEKTNLNPSSPYSASKAS
                     ADLLTISYYKTYGLPVTISRCSNNYGPYHFPEKLIPLVIHRALENKELPIYGDGKNVR
                     DWLHVYDHCTAIDLIVHKGKSGNIYNVGGHNERSNLEVVKTILDTLGKSEDLISFVAD
                     RKGHDLRYAIDASKLEQELGWKSIYSFDEGIKHTIKWYLENQEWMESIISGEYKNYYS
                     NMYKNE"
     gene            10260..11048
                     /locus_tag="KR294_002342"
     CDS             10260..11048
                     /locus_tag="KR294_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012425455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0240414.1"
                     /translation="MSLVKELYRNRDLILNLSKNDFKTKYAGSYLGIFWAFVQPVVIV
                     LIYWFVFQVGFKAAPVKDFPFILWLIAGIVPWFFFQEALINSTNSLLEYSYLVKKVVF
                     KISILPLVKIISALYVHIFFICFALASYCIYGIYPNIYIIQILYYSFCTMFLALGISY
                     ITASIIPFFKDLSQIISIFLQIGMWATPIMWSYNIMPTKYQWFLKLNPMYYIVEGYRD
                     TLVNNVWFWERYNQTLYFWTISIIIFFVGIILFKKLKPHFSDVL"
     gene            11062..12330
                     /locus_tag="KR294_002343"
     CDS             11062..12330
                     /locus_tag="KR294_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015543312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0240415.1"
                     /translation="MNEIVIKVENISKVYKLYEKPIDRLKETIGLSKKVYHTKHYALE
                     NLSFQVEKGETIGIIGTNGSGKSTLLKMITGVLTPTSGNIIVNGKISALLELGAGFNP
                     EYTGIENIYLNGTMMGYKKEEMDDKIESILEFADIGEFINQPVKTYSSGMFSRLAFAV
                     AINVEPDILIVDEALSVGDVFFQAKCYKKFNDFKKQGRTIIFVSHDMGSIMKYCDKTL
                     LIDRGKFVDMGPSANMIDIYKKILVNQYVPDSDNEEIIEDVMEIEGTNKWYEKLQINP
                     TKLEYGNKKAEIIDFAIVDDKNKINNNINKGTIFNIKMKVKFNENIDNPIYAFTIKDL
                     KGTDVTGTNTMLEHIDTNKYDDKGEVIIVFKQKMDLQGGSYLLSLGCTGYESEDFTVY
                     NRLYDICNINVISLKNSVGYYDMNSEIEIY"
     gene            12358..13266
                     /locus_tag="KR294_002344"
     CDS             12358..13266
                     /locus_tag="KR294_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012060902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBH0240416.1"
                     /translation="MEKYIGNIKLNFDFYKGNDLYSDGVVEDELLDIVKNYSEYEDII
                     KERKEWPIIYHLSKIRENIIEWIPINKTDNVLEVGSGCGAITGILSKKAKQVDCIELS
                     QKRSYINAYRNKSKSNINIFVGNFEDIEKNMTEKYDYITLIGVFEYAESYINSKKPYI
                     EFLRIVKKHLKKNGKIIIAIENRLGLKYWAGCKEDHLGTYFEGLEGYREDKGIKTFSK
                     NELEDIFKLVGFYKYNFYYPYPDYKLPITIYSDEYLPKLGELNNNFRNFDLDRVVTFN
                     ETEVFDSIIKNNLFPIFSNSYLIILE"
     gene            13285..14667
                     /locus_tag="KR294_002345"
     CDS             13285..14667
                     /locus_tag="KR294_002345"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240417.1"
                     /translation="MSKIIYSKYSNERNKKFQIRTSILQNDDGKKIVKKLAIVDESKK
                     HIDDIFENFERLKDNYYLDERVKINLCNKTEDGLEFEYLEGMTLDKIIDDFMENNEYD
                     KSIEIIKDFRNVIFNVSTTCGFNITEDFIKVFGNVDFNSDTKATLLSNIDSSFNNLVI
                     NDAWNIIDYEWVYKFPIPIRYILYRALNIYITTSVYGSKLKDLNIYDILGYSELELSK
                     YEFMEYNFGRYIAGESISLQNLYEDIKTKKYKLEELLISNDFNKRMQIFYDEGNGFSE
                     ENSYYIDLEMKNKITIPLEKDIKSIRIDPASVNCIILINKLDVVFANETIDIKNNLIT
                     NADEKKQDLYTFLSSDPQIYIDLGNRFQKGYINFEYEIKKLDFDTYDIYLEVRNLMLN
                     NQNKLINLNKELEERNMQLDILGKEINQINDRLENTLNELDNAKNKIYILEKRKIKNI
                     LRNMKKRISK"
     gene            14701..15861
                     /locus_tag="KR294_002346"
     CDS             14701..15861
                     /locus_tag="KR294_002346"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240418.1"
                     /translation="MHFFTSITTNYLPKARVLANSVKKNCENSWFILVVCDNLPNDFN
                     LEKEPFDEVWTIESLGLPVENLNMWIFQHTVVELCTAVKGQAMLNLLNKYEKCVYLDP
                     DMVVFDSLKELENLLDSHDIILTPHVTHKEEEEQHIRNNEIASLRYGAYNLGFLAVKR
                     NENGLEFVTWWRDRLCKYCFDDIPGGLFTDQKWIDLAPGLFEGVYILRDPSYNVATWN
                     ITWRKISNLDGKYKVNNIDLKIYHFSGFDSGAQEIMLKVNGGNNQALWNLREQYILEQ
                     EKNGQKELGSLKGKFDTFDNGEIISKDMRVLMRNRLDLQDYFKEKNPFCSVGEKSYYN
                     WYKNNVSFRLDDETLDEKSKKILELENELNRLRKMISPLQQIKKILKKFLKR"
     gene            15872..19420
                     /locus_tag="KR294_002347"
     CDS             15872..19420
                     /locus_tag="KR294_002347"
                     /inference="COORDINATES: protein
                     motif:HMM:NF012744.1,HMM:NF025665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 99-like
                     domain-containing protein"
                     /protein_id="HBH0240419.1"
                     /translation="MNNRDKNILFLIHDYIKYDTPMNVGGTQLHIEDLISKIENETFY
                     ILYKKKNKLILDEYRDSKLINTYNYYCGDLSSVVEYTNPLFKLIYSAILVNFKIDLIH
                     IHHLKNHTFDIIYEAKSLNLPIIITIHDYYLVCPKINLIDRNNCCCVNRETKELCGEC
                     MSEEIGMSFEELHLYREEVSKILLMCNEVIIPNKSVSEVLLIHYYCIKEKIRVIEHGQ
                     TGEVSKYAPTYKNGKFNVAFVGGLKPCKGSKEIIKIIKNCTDKDINFFVFGTIDDKDF
                     DDIPSHNINCTGNYFRKDIYKLLEENEIHIVCILSIWPETFCYTLSESWQCNIPVITV
                     DIGATGERVKNGGGILITGNNIGESTLKSIIELKNDRNKYESLCKTVKNIKLRDIGEM
                     SKDYSNLYFSYMKNVMLDNKISSELILDALKNIDLFQTNNSIKNYELEDLKNEIKYIK
                     GTFAYRVWQKYKDMKIPFKSNISSFFKRKVSLEKDISKNKNIIKRKSEQLNIISNIEY
                     EQVYYENEKLNFYVEGWFFSKYYDMNVSCENCESFSIERLSRPDVQSHFGGKKEAENS
                     GYRIAFIGVEENSKISLVFDIGNLKKYYNFNVDTSQGVVYIGKYPKKLRWKSIPQLFD
                     MTVVEPYKYKKVIDKNSETIENVSLILNATRPIKKEWAEETIRSIINQGFKSLYIISC
                     NENLNLFSEIDNIMLVSSKLLTRKEECLEFLTSKYDFNCEYVSFISIGDKMEVNTIRE
                     MIKEAKKSNSFIVTTNENRFFEEEYFAPFYKQQLYNRFDNPSIDRLCRKSMLISTDKI
                     IDFISGNIKSNEIKIIDKILYNYRLYNDNIDNKVKVLAYYLPQFHTIPENDEWWGEGF
                     TEWVNVNRGRPMFKGHYQPHVPGELGYYNLVKDEGIQKKQSQLANDYNIYGMCYYYYW
                     FNGKKLLEKPLENLIADKSINTNFCICWANENWCRRWDGLENEILIKQEHNVQSDKRF
                     IYDVLPILKDERYITIDNKPILLVYKSDLFPNFISTVESWNKICIENGLEGLEVITVQ
                     TGGLEDPRNMGCKYAVEFPPHNIYSRVLSAKSKVEELDKDFEGTILDYSEVAGIGMNK
                     KAQPYTFFRGVMLSWDNTARRNTQSRIFYGSNPNEYKKWIASVIDFSINFYEEKERMI
                     FINAWNEWAEGTHLEPDEKYGHKYLEVTKEVLGAQY"
     gene            19598..20968
                     /locus_tag="KR294_002348"
     CDS             19598..20968
                     /locus_tag="KR294_002348"
                     /inference="COORDINATES: protein motif:HMM:NF025665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 99-like
                     domain-containing protein"
                     /protein_id="HBH0240420.1"
                     /translation="MNKLNSLIKRLYHMLPLSYEKKILLKNNVYKLLSPFIKNTNMYS
                     IWINSLENPEKYIKDNNPKKGVDNEKDIYIDNLFKRASEKSSNYIEISDTRFQLEKND
                     IKLISFYLPQFHPIVENDEWWGRGFTEWTNVSKAVPQFLNHYQPHLPAELGFYDLRLK
                     EVMKRQIELAKMYGIYGFCFHHYWFAGKRLLERPVNMLLKDKELDIPFCLCWANENWT
                     RRWDGLENEVLIEQKHSKEDDLEFIKDISNYFKDERYIKIDGKPVLIIYRIELLPNPI
                     ETIKLWRKYCLEIGWNDIFIVGAQTFGFEEHIKYGMDAGVEFPPHNINNCPILNKEIN
                     FTNKKFTGLVYDYKKLVDDKLYIKKSHGKVFKTVMPSWDNTARKPNNASIFKNSTPEL
                     YKKWLKDIIYSTKENVLDSDNFIFINAWNEWGEGAHLEPDRKYGYSYLNATREAIIET
                     RSEKNN"
     gene            21009..22805
                     /locus_tag="KR294_002349"
     CDS             21009..22805
                     /locus_tag="KR294_002349"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240421.1"
                     /translation="MDKLKKNNNLKIKIIFFILLQIFFIFFLVVNFKTPLLGEDYALL
                     YNGPFKDIGDYFSTIMAALEKQMSTWMVRMGNPLTIIWLSFDKSIYNIAVSFVSMIFF
                     FLIFFYGNARKPNVNNLGDLIGFFVPASLMMFLSPSIGDLFFWCNGSLNYLWPLCILL
                     LCAIPYRLYLSEKNINIKNPILIILYCIACFISGFTNENTPPVIITLVAALIIRDLYL
                     KKKPPKWIVFSFISICAGWIGLVVNSTTRFRSMYYRNMFGLPEHATINELINNVLRVG
                     YLFLKSGFAFVIIFLILSLLFIFILKSQKTENEFKYKHLFAENMFFILLTFISAAALV
                     FAPYTELRSFTLIHTIILATISNLLVNLYEISSHKQRLGLSSISIITLLSTFLLFINI
                     YNEYNDYYKFDTQRTCDIKSQVAAGKTTVYASKNFIENRTMNNREFYIYGNDLGQGGN
                     FYSDYFGAKKIIWYDKIDSNIDPATINLSSESTDVNVELINGNSEQDNSSLLSDGIFN
                     VSGWAIDKVAGNSPSKVFIKIDDKYYQARTVIREDVAKYFDNKKYKKAGFECSIPTKD
                     IKKGKHKVTLCVISNDGEKRYEVDSGKSIEFK"
     gene            22836..>23434
                     /locus_tag="KR294_002350"
     CDS             22836..>23434
                     /locus_tag="KR294_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiA family prenyltransferase"
                     /protein_id="HBH0240422.1"
                     /translation="MASLIKQRKYNRNILLEYIKLMRPKQYIKNGFVLAALIFSNNIL
                     NPSLALKSILSFIAFCMISSSAYILNDILDIEKDKMHPKKCKRPLASGSIGKKGAISL
                     GIVLVLSSILLSLLIHKNLCVIILLYLFNNIMYSLKLKNIILIDVFSIAIGFILRVCA
                     GSIAINVSLSSWIILCTFFLSLYLGFGKRKKEIILLKEDA"
BASE COUNT         9444 a         2150 c         3864 g         7976 t
ORIGIN      
        1 cttttatgta tacataaata tatgccaata ttttacatgg aaaaaaatga ttaatttttg
       61 tataatgaaa taaagattct aataaagcca gagttatcat atacattgaa ataatattat
      121 atttgtatta taatttatag ataataagta attttaaaaa tagaaatata cataattcat
      181 atatctaaac aaagtttatc tatgctatgc aatatcaaat attttaatgt tgtgtatgat
      241 gattctagag tcttgaaatt tttataatta caatttatat tgacacttaa gttgtttaat
      301 aagtaagagc attaaatgaa atatattaga aattgagggg agtacaagtt atgaatatac
      361 caaaaaaaat tatatcgtta ttgacaataa caataatgtt aagcggatta tctttaaata
      421 cagtaaatgc ttcaacaaaa gaatctttag ttggtagtgg aagatgggag actgctatac
      481 aaataagtaa aaatggttgg gaaaattcaa aagaagcagt attagtcaat gatagttcaa
      541 tagcagatgc attatcagca acaccattcg caaaagctaa aaatgctcca attttattaa
      601 cacaaagtaa tagtctggat gcaaggacta aagctgaatt aaaaagatta aatgtatcaa
      661 aggtctattt aataggagga aatgttacac taagttctaa tttagagtat gagttgaaaa
      721 gtataaatat taactcagaa agaatatctg gagatagtag atattctact tcgttagaat
      781 tagctaaaaa gatagatagt ataaacacta tttctaaaat tgttgttgta aatggtcaaa
      841 aaggtttagc tgatgctgta agtgttggag ctgcagcagc tcaaggaaat atgcctataa
      901 tactttcaga tactactaat ggaactagca cttcaaaaga ttttataagt aaacataata
      961 taacgacatc ttatgtaatt ggtggtacta attctgtatc tgaggacatt aaaaattcgc
     1021 ttcctaatgc taaaagaatt tctggagaaa atagaaacca aactaatgca aaagttgtag
     1081 aagaatttta caagggtaca aatttaaaaa atttatatat aactaaagat ggtatgaaaa
     1141 aacagggtga cttaattgat tcgctagctg ttggtgtttt agctgctaaa aatagttcac
     1201 ctgttctttt ggcaggaaat aaattggact cagttcaaaa ggatatacta gataccaaaa
     1261 tttttgataa gattacacaa gttggtggaa atggaaatga agatgttttt aagtcaatac
     1321 aagatattca agaagaaact aagtacacag ttgaaacaat ttctgaactt gatacagcta
     1381 taaaaaaatc agatgctaat gatattataa gatttaaaaa tgatgataaa ataactggct
     1441 caattgatat aagtacaaaa aaagctataa caattgaatt caatggatta tatagtggaa
     1501 aagtaaatat aaatatacca aatggagatg tatataatta tggagatatg actggccaga
     1561 tggatattaa agatataaaa actgacactt tagtaaatga agggtcaatt aatgagataa
     1621 ctatatatga cccaaatggt tgtaaaatag aaaatgaaaa agatgctgat atttggaaaa
     1681 taacattact ggatacatct aagaatacct atataaataa tagtggaact ataactaaaa
     1741 tagttagtga tgcatcaaat acaactataa aaaattcagg aaagattgag ttaataagtg
     1801 ggactaagtc tccagcagta agtggtaatc aagccactga tgaaaatata aaagataatg
     1861 atgacaaaga agcaggagga atttctgtat atgtagatcc atgttctcct ccaaaagaag
     1921 gaaaggtaat gttaagaata ccaaaagaac caagaagttc tagttataac atatactaca
     1981 gaattgttaa atctagacca tctgcaatgg atgtaggaga tactatatca aaaaggggtt
     2041 ggactaaagt gactactaga gattcattta tgattagtgc gacagatgga tattatgtag
     2101 aagctgtaga aatctatgat tctgatagaa aggtaagtaa gtggggaaga tcaggaagta
     2161 tagatgatgg atataacaat acaacttcat cagcaacatt aagaagttat aaataaaata
     2221 ttgatatgca tataaattaa gaaggatttt ttgtggttgt tagtttctat gtatttatga
     2281 tataaataat ttaaaaatga gttatataaa cttgttacat taattaattt taattattgt
     2341 gaagttatta tatagcttat ttttatgaaa aagtttaatg tacaatttaa ggtgagtata
     2401 ctacttttga tataaaactt ttaaaattat tattcaataa agttttaata atttcaaaag
     2461 tagtgtatac tcattttatg aagaatttta atgaaataag aataaataag gaggaaagag
     2521 taagttgaat ataactaata aatgtgtttt aggaatatct attttagcta ttttgagttt
     2581 tggattttca gcgtttcaag gtaatgctca aattactgat agaaaaaaag attatgatat
     2641 atatctaaaa gcgaactctg ataaaagtga tgtaaaatcg tctttaaatg atatttctaa
     2701 gttagagaaa aaatatggag aaagtgatgc gttgagtata tctaagatta atttatatga
     2761 aaagatgaat gattataaaa atttacaatc tgaaattgag aaagtttaca atagatatcc
     2821 tcaaactaga aatacagttt catttgtact tttatattct gaagttgctt taaaaaatgg
     2881 aaacaaagaa ttgtcaaaga atatgattaa tgaagcaatt aaattaggag cacaagatgc
     2941 ttataaagaa agagtggata aggtattatc acaattaaat taaaaggaga aatatatgtt
     3001 agataaatat tacaatagag gaaaagttga acaaatagat aaatttattt tgtttatatt
     3061 attatttatg atgtgtatta ttccaataat aactcatgaa tatacttcta caaactatag
     3121 tcctattttt acattaacat tgtattcttc aggagaaagg gtagaaatat ttaattttta
     3181 taaaacagca atattgtatt tggggacaat gatagttttt tgttttttta tgtataaaat
     3241 ttttgtactt aaagaagaat taaaaaaaag aaaagttaat ataatattgc ttatcttagc
     3301 aataggagta atattatcgt ctgttttttc tgattataaa gatatcgctt tatttggaaa
     3361 tcctgataga tttgaaggag ctttggcttg gttttgctat atagttatat tttttgtgtt
     3421 gtataatatt aagatagatg taaaagattt gaaattattt tattttggat tgtttccttt
     3481 tttagttata aatttattct taggattagc tcaatttttt gaaattgatg ttttacaatc
     3541 taaaatttta actactctta ttggtggagg aactttatct ggaacatttt ggacaacttt
     3601 ataccatttt aatatcatga gtgggatagc atctgtcatt ttttgtgcta gcttagtata
     3661 tatgttattt gaaaaagata ttaagaaaaa aatagtacca ttatttggag caattatgtc
     3721 atttacaata attcttatat cgaattctat aagtggtttt ttaacatcta tattattatt
     3781 cccaattata ttagttttat cttggagatt tgtgaataaa aaagaattat gtgtatggac
     3841 aattattatg gttataatta gttccattat atatattata ttaaatagac ataacccaaa
     3901 tgtttatcaa gaaacatttg ctatgtttga aaaattaaac caagcatcaa tatttatagt
     3961 tcctatattg atagtaacat ttatattgtt gattattata atgaaattta taaataaaaa
     4021 gaaatttttt aattttgtta ctgtatgttc tattgttata gtctcagctg gattattatt
     4081 tttttcatat acactaaata aagaagtcag tattttagaa agtaatccaa atgctaatat
     4141 tactagaata gaagattcta aattatttaa tataataaat ggtatgagta cagatcgttt
     4201 aaacatatgg actaaagtta tgaattttat aaatgaaaga cctatattgg gaaatggatt
     4261 tgatactttt ccatataaat tcattagtac agataaaaat ggtgctttaa gtacatatgg
     4321 agaggttata gataaaccac atagctggta tatgagtgtt gcatatggaa gtggtataat
     4381 tggtataatt ggtttagtgg gtataataat atatttaact aaagaagttt tctatagttg
     4441 tgtggataaa aataatgata aatttctata tatatttttt attggctttt tagcatattc
     4501 tattcaaggg ttatttaatg atagccttgc aggatcttca ataataagtt gggtttttgc
     4561 tggtttaact gctaatagaa tatttacaat aaagtctaaa taaattttaa aaatggcata
     4621 gtggactaat tatagaaaac tatgtcattt tattttaaaa aaatagatat tatttttagt
     4681 tagtatttta atctatctac aaataatata aaataataga tgtatgttta taatttaaaa
     4741 aaaatcaaaa tctaaagtaa aatgtgtaga atcattaaat aaatcaaaag gggatgatag
     4801 tttgaatgtg agtataataa taccaactaa gaatgcagaa aagtatatag agaatcttat
     4861 aaaagcacta ataaatcaaa ctatagaacc ttgtgagata atagttatag atactgaatc
     4921 gaaagataaa actgtagaaa tttgtatgga atacgatatt gtcaaattta tacaaataaa
     4981 acaaagtgaa tttggtcatg gttcaactag aaatagagct gctaaattaa gtaaaggtga
     5041 tattctagtt tttatgacac aagatgcttt gccacaaaat tgttatttta tagaggaact
     5101 aataaaacct ttaggtaaaa ataatattgt atgtacttat ggaagacaat tgccaagaaa
     5161 taatgcaaaa acactagaag tattttctag aagctttaat tatggaaata gtgatataat
     5221 aaaatctaaa gaagatattc ctaaacttgg agtaaagact tttttcttta gtaatgtttg
     5281 ttcttctttt ataaaaagag actttttttt ggttgatgga tttccagaaa atataataat
     5341 gaatgaagat atgataatat cttctaagat tatatataat ggtaaaaaaa cttgttatgc
     5401 atctaaggct attgttacac attcacatag atatacatac ttacaacaat ttaaaagaaa
     5461 cttcgatata ggtgttgcat ttaaagaaaa tagttattat ttaagtgaag taaagtctga
     5521 gtcagagggg tttaagtttg tcatagaagc cattaagttt ttatttcaaa gtaataaatg
     5581 ttatttgatt cctagcttgt tcatagaaag tggatttaaa ttttttggat ataaatttgg
     5641 tatgaattat aaaaatatgc ctataaaatt agttaaattg atgagcatgc attcttttta
     5701 ttttgataga aaagaagtta tggaggagta ttatagtgaa aatagtaata acaggtgcta
     5761 agggacaatt aggtttagag atagtaaatc aattggataa tttgaataat ataagagaaa
     5821 aaaatatata tgatatagtt ccaacagata gaagtaactt aaatattact gacctagaaa
     5881 atgttaataa ttttattttt aaagagatgc cagatgtcgt tataaattgt gctgcttata
     5941 ccaaggtaga tttatgtgaa aatgatatag ataatgcata caaagtaaat gccttaggtg
     6001 ttagaaattt ggctacagcc tgtgaaaaaa taaaagctaa atttgttcaa atatctactg
     6061 attatgtatt tgatggaaat agcaatatac cttataagga agactgtatt acttttccaa
     6121 attctatata tggaaagagt aaattaatgg gtgagtattt tacaagacaa ttttcttcaa
     6181 aatattttat aattagaaca gcttggttat atggagatgg tgataacttt gttagaacca
     6241 tgcttaattt agcaaaaaat aataatgaaa ttaatgttgt ttatgatcag attggaagtc
     6301 caactagtac tgttgaatta gctgaagcta taattaattt gattgaaaca gattattatg
     6361 gaatatacca tggtacctgt gaaggtgaat gtagttggta tgaatttgcc aacaaaatat
     6421 ttgagttaag taaaattact gttaaagtta atccaataac aagtaatgaa ttcaaaagag
     6481 aagcacctag accaatgtat tcagttttag ataattttat gttaaaatta attggattaa
     6541 ataattttaa tagatgggat gaagctttaa aaaagtattt agaataaaaa ataaatttgt
     6601 ttggaggata aattatgaaa ggaattgtgc tagcaggcgg atctgggact aggttatatc
     6661 ctataactaa atgtgtgtct aaacaagtac taccaatata tgataagcca atgatttatt
     6721 atcccatatc agtgcttatg ctttcaggta taagagatat actaataatt tctactgtca
     6781 gagatataaa aatttttaaa gaattgtttg gagatggatc tcaattagga gttaatatac
     6841 aatacgctat tcaagaaaaa ccaaatggta ttgcagaagc atttattata ggagaggact
     6901 tcattggaga tgataaagta gctcttgttt taggagataa tatattttat ggttatggat
     6961 ttagtgaacg attagagaga gctattaata gagatgaagc tactatattt ggatatcatg
     7021 taagtgaccc gacatctttt ggtgtagtag aatttgacaa agattttaat gtactatcaa
     7081 tagaggagaa acctaaaata cctaagtcta actatgctgt tccaggtctt tacttttatg
     7141 ataatgaagt tataaagatt gctaagagta taaaaccttc taaaagagga gaattagaaa
     7201 taacttctgt aaataatgag tatttaaaaa agggaaagct taaagtagaa ctttttggac
     7261 gtggtatggc ttggctagat actggcacac atagagggct attagatgca tctaattatg
     7321 tagaagttgt tcaaacaaga caagggttat atattgcttg tttagaagaa attgcttata
     7381 ttaagggata tataacaaaa gaagatttac tagaacttgc taagccatta atgaaaaccg
     7441 attatggtaa atatttgata aaaatagcta atgaatttaa agaaaataaa tgaaaataag
     7501 ataattatta aaactgtatg aatactataa tataaaaatg acaacttagt ttatataata
     7561 tttgattgta taaattaagt taaattatgt actaaatatt taaacaataa gaaggtgtaa
     7621 ttttgaatat taaaaaaaaa tttaaaattt gtattctact tatacttgta tgtatgttat
     7681 ttttaggagc ttggtctaaa atgaattctt ggagagacac attatataca cctacatcaa
     7741 tagaaaaaat agatgattta tatttcatag tagattgttg gcaacaccgt gttatatata
     7801 atgacaatct tagtgacaaa atatctaact ggaagacttt aagtgacaat ttagaaggtc
     7861 ctcattctat tgcaagtgat aaagaagtat ttctggtaga taatacagaa aagaatgaaa
     7921 tccaagtttt taaaagaaaa gaagataatt ttatattaac tcaaactatt caaaatgttg
     7981 ggaaaagacc acataaaatc atatatgata agaatacaaa tttattttac agtattgcta
     8041 gtacctcaca agatatagta gttcttgaaa atatcaatgg gaatgtaaga gttaaacaaa
     8101 aaactaggtt agattttctt gatggatctt acataaggtc aatttctatt attgaagata
     8161 aaatgtattt tttaccaggt cctaataagg tgatttgtac agactataaa agtggaaaat
     8221 ttaatgtgat ttctgaatat aagcttccaa aagctttaga agcaataaat catctttata
     8281 aaatagataa ttattattac atatcacttt acacaatggg tgaaaatcct aatgaaccta
     8341 aattagttag atttaaaaat tttaatgaac ttcaaaataa tgaatatgaa gatcttacaa
     8401 aaaaactaaa tattaaagga gtaccttact ttttttcaga gtttgatggg aaagtatttt
     8461 ttacagaaat agactcttat tcagagatta aatcatttaa agtaaataat gataatatag
     8521 atagtattgt gaattattat gattcaggca aaccatcaaa agaatctatt gaaagaaaga
     8581 aaagtatttt aagatagata tcaatgatta aatattattg tataataaag gagaaatact
     8641 atgagtaagt ttaattttat agaaacaaaa ttaaaagatt tgtatataat agaacctaca
     8701 atatttggag atagtagagg atattttatg gaaacctaca ataaaagaga gtttttagag
     8761 gctggacttg atatggagtt tgttcaggaa aatgaatcta aatctaaaaa aggtgtttta
     8821 agaggattac attttcaaac tgaaaatgtt caaggaaaac tagttagagt agcttttgga
     8881 gaagtgtatg atgtagctgt tgatttaaga attggttctc caacttatgg actatgggaa
     8941 ggtgttatac tatcatcaga aaataaaaga caattttatg taccagaagg ttttgcacat
     9001 ggatttttag tactatctaa cgaagctgtc tttaattata tgtgtactaa ttattataat
     9061 gctgattatg aaggtggcat attatggaat gataaagata taaatataga atggccttta
     9121 gataaagtag acagcgttat attatctgaa aaagataaaa aactattaaa gttaagtgaa
     9181 ttagatttac aatttaaata tggaggtgag tagaaaatga gtaaagtttt aattactgga
     9241 ggcgcgggat ttattggtgg aaattttgtt cattatatct tagataaata tcctaaatat
     9301 gaagttgtaa atttggattt gttaacttat gctggtaact tagaaacatt agaaaatata
     9361 aaacataaac ataattataa atttgtaaag ggtgatattt caaataggaa ttttatattt
     9421 gatttatttg atgaagaaag atttgatata gtcataaatt ttgcggctga atcacatgtg
     9481 gataggtcta tcaaagaacc gtggaaattc attaatacaa atgttattgg aacacaagta
     9541 ctgctagatg cttctaataa atatggtgta aatagatttc atcaaatttc cactgatgaa
     9601 gtttatggag atttgccact tgatagattg gatttacttt ttactgaaaa aactaactta
     9661 aatccaagtt caccatattc tgcttctaaa gcatcagcag atttattgac tatttcatat
     9721 tataagacat atggattacc tgttactata tcaagatgtt caaataatta tggaccatat
     9781 cattttcctg aaaaactaat acctctcgta attcatagag cattagagaa taaagagtta
     9841 cctatttatg gagatggaaa aaatgtaaga gactggttgc atgtatatga tcattgtaca
     9901 gcaattgatt taatagttca taaaggtaaa agtggaaata tttataatgt aggtggacac
     9961 aatgaaaggt ctaatttaga agtagttaaa actattttag atactttagg taaatctgaa
    10021 gatttaatat ctttcgttgc agatagaaaa gggcatgatt taagatatgc tatagatgca
    10081 agtaaattag agcaagaatt aggatggaaa agtatatata gttttgatga aggtataaaa
    10141 catacaataa agtggtattt agaaaatcag gaatggatgg aaagcataat atctggagag
    10201 tataaaaatt attatagtaa tatgtataaa aacgaataat attgattgga gaaattaaaa
    10261 tgtcattagt aaaagaatta tataggaata gagacctgat attaaactta tctaaaaatg
    10321 attttaaaac taagtatgca ggttcatatc ttggaatatt ttgggcattt gtacaaccag
    10381 tagttatagt tcttatatat tggtttgttt ttcaagttgg ttttaaagcg gcacctgtaa
    10441 aagattttcc tttcatatta tggttaattg caggaatagt cccttggttc ttttttcaag
    10501 aagcactcat aaattccaca aatagtttgc ttgagtatag ttatttggtt aaaaaagttg
    10561 tatttaaaat aagtatacta ccattagtaa aaatcatatc tgctttatat gtacacatat
    10621 tttttatttg ttttgcacta gcttcttatt gcatatatgg tatatatcca aatatctata
    10681 taattcaaat attatattat tctttttgta ctatgttttt agctcttggg atatcataca
    10741 taacagcttc tataattcct ttttttaaag atttaagtca aattataagt atatttttac
    10801 aaattggaat gtgggctaca ccaataatgt ggagttataa tataatgcca acaaaatatc
    10861 aatggttttt aaaattaaat cctatgtatt atattgtgga aggttataga gatacattag
    10921 taaataatgt ttggttttgg gaacgttata atcaaacatt atacttctgg actatatcta
    10981 taatcatatt ttttgttgga ataatattat ttaagaaatt aaaaccgcat ttttcagatg
    11041 tgctgtagaa gaggtataca tatgaatgag attgttataa aagttgaaaa tataagtaaa
    11101 gtgtataaat tatatgaaaa gccaatagat agactaaaag agactatagg gttatcaaaa
    11161 aaagtatatc atacaaagca ttatgcatta gaaaatcttt cgtttcaagt tgaaaaagga
    11221 gaaactatag gcatcatagg tacaaatggt tccggaaaat ctactttatt aaagatgata
    11281 acaggagtat taactccaac aagtggtaat ataattgtca atgggaagat atcagcctta
    11341 ttggaattag gagctggatt taatcctgaa tatacaggta tagaaaatat ctacttaaat
    11401 ggtacaatga tgggatataa aaaagaagaa atggatgata aaatagaatc aatactagaa
    11461 tttgcggata ttggtgaatt tattaatcaa cctgttaaaa cttattcaag tggtatgttt
    11521 tctagattgg cttttgcagt agcaattaat gttgaaccag atatacttat agtagatgaa
    11581 gcacttagcg taggagatgt tttttttcaa gcaaaatgct ataaaaaatt taatgatttc
    11641 aaaaaacagg gtagaactat tatatttgta agtcatgata tgggaagtat aatgaaatat
    11701 tgtgacaaga cattgcttat tgataggggc aaatttgttg atatgggccc atcagcgaat
    11761 atgattgata tatataaaaa aatattagtg aatcagtatg ttcctgatag tgataatgaa
    11821 gaaattattg aagatgttat ggagattgaa ggtacaaata aatggtatga aaaattacaa
    11881 atcaatccta caaaacttga atatggaaat aaaaaagcag aaataattga ttttgctatt
    11941 gtagatgata aaaataaaat taataataat ataaataaag gtacaatatt taatataaaa
    12001 atgaaagtta aatttaatga aaatatagat aatccaattt atgcattcac aataaaggat
    12061 ttgaaaggta ctgatgtaac aggaacaaat acaatgttgg aacatattga tacaaataaa
    12121 tatgacgata agggtgaagt tataatagta tttaagcaaa aaatggattt acaaggaggt
    12181 tcatatttat tatcattagg atgcactgga tatgaaagtg aagattttac agtatataac
    12241 aggttatatg atatatgtaa tataaatgta atatcattaa aaaatagtgt tgggtactac
    12301 gatatgaatt ctgaaatcga aatttattaa gttataattg aaaggtagtt ttagaatatg
    12361 gaaaaatata taggtaatat aaaattaaat tttgattttt ataaaggaaa tgatttatat
    12421 tctgatggag tagttgaaga tgaacttttg gatattgtaa aaaattatag tgaatatgaa
    12481 gatattataa aagaaagaaa agaatggcca attatatatc atttatctaa aataagagaa
    12541 aatattattg aatggattcc tatcaataaa acagataatg ttttagaagt aggttcaggg
    12601 tgtggtgcaa ttacaggaat attatcaaaa aaagcaaaac aagttgattg tatagaatta
    12661 tctcaaaaaa gaagttatat caatgcatat aggaataaaa gtaaaagtaa tataaatata
    12721 tttgttggaa attttgaaga tatagaaaaa aatatgactg aaaagtatga ttatataact
    12781 ttaataggag tatttgagta tgcagagagt tatattaatt ctaaaaaacc atatattgaa
    12841 tttcttagaa tagtaaagaa gcatctaaag aaaaatggta aaattattat tgcaatagaa
    12901 aataggttag gattaaaata ttgggctgga tgcaaagaag atcatttagg aacatatttt
    12961 gaaggtttag aaggatatag agaagataaa ggtataaaaa ccttctctaa aaatgaactt
    13021 gaagatatat ttaagttagt tggtttttat aagtacaact tttattatcc atatccagac
    13081 tacaaattac caataacaat ctattcagat gaatatctac ctaaattagg agaacttaat
    13141 aataatttta gaaattttga tttagataga gtagttacat ttaatgaaac tgaagtattt
    13201 gattctatta ttaagaataa cttatttcct attttttcaa attcttattt aataatatta
    13261 gaataaaagg aagtgaaaat ccagatgagt aaaattattt acagtaaata ttcaaatgaa
    13321 agaaataaaa aatttcaaat aaggacaagt atattacaaa atgatgatgg aaaaaaaatt
    13381 gtaaaaaaat tggctattgt agatgaatct aaaaaacata ttgatgatat ttttgagaac
    13441 tttgagagat taaaggataa ttattatctg gatgaaagag taaaaataaa tctatgtaat
    13501 aagactgagg atggtttaga gtttgagtat ttggaaggta tgacattaga caaaataata
    13561 gatgatttta tggaaaataa tgaatatgat aagtctatag aaattattaa agattttaga
    13621 aatgtcattt ttaatgtgag tactacttgt ggttttaata ttactgaaga ttttataaaa
    13681 gtatttggta atgtagattt caattctgac acaaaggcca cactattaag caacatagat
    13741 tcttccttta ataatcttgt tattaatgat gcttggaata taattgatta tgaatgggta
    13801 tataaattcc ctataccaat aagatatatt ttatacagag ctttaaatat ttatataact
    13861 acatcagttt atggaagtaa gctaaaagat ttaaatattt atgacatatt aggatatagt
    13921 gagttagaat tatctaagta tgagtttatg gaatataatt ttggacgtta tattgctggt
    13981 gaatctatat cattacaaaa tttatatgaa gatataaaaa caaaaaagta taagttagaa
    14041 gagttattga ttagtaatga ttttaataaa aggatgcaaa tattctatga tgaaggcaat
    14101 ggctttagtg aagaaaactc atattacatt gatttagaaa tgaagaataa aattacaatt
    14161 ccattagaaa aagatattaa atctattaga atagaccctg cttctgttaa ttgtattatt
    14221 cttataaata aattggatgt agtttttgca aatgaaacta tagatataaa aaataattta
    14281 attactaatg cagatgaaaa aaaacaggat ttatatactt ttcttagcag tgaccctcaa
    14341 atatatatag acttagggaa taggtttcaa aaaggctata taaactttga atatgagatt
    14401 aaaaaacttg attttgatac atatgatatt tatttagagg tcagaaattt aatgttaaat
    14461 aatcaaaata agttaataaa tctaaacaaa gaacttgaag aaagaaatat gcaattagat
    14521 atactaggta aagaaatcaa tcaaataaat gatagattag aaaatacact aaatgaactg
    14581 gataatgcaa aaaataaaat ttatatatta gagaaaagaa aaataaagaa tatattgaga
    14641 aatatgaaaa aaagaattag taaataatta ttttatttca aaagaaggag tattaaaaat
    14701 atgcattttt ttacaagtat tactacaaac tatttgccaa aagctagagt attagcaaat
    14761 tctgtaaaga agaattgtga aaactcatgg tttattttag ttgtatgtga taatctacca
    14821 aatgatttta atttggagaa agaacctttt gatgaggttt ggactattga gagtttagga
    14881 ctacctgttg aaaatttaaa tatgtggatt tttcaacata cagtagtaga attgtgtact
    14941 gccgtcaaag ggcaagccat gcttaattta ttaaataaat acgaaaagtg tgtgtattta
    15001 gatcctgata tggtagtatt tgatagtttg aaggaacttg aaaatctttt agacagtcat
    15061 gatataatat taacaccaca tgtaactcat aaagaagaag aagaacaaca tattcgtaat
    15121 aatgaaattg catcactacg ttatggtgca tataatttag gatttttggc tgtaaaaaga
    15181 aatgaaaatg gtttagagtt tgttacatgg tggagagata gactttgtaa atattgcttt
    15241 gatgatatac caggaggact ttttactgac caaaaatgga tagatcttgc accagggcta
    15301 tttgaggggg tatatatatt acgagatcct tcatataatg tagctacttg gaatattaca
    15361 tggagaaaaa tcagtaattt ggatggaaaa tacaaagtta ataacattga tttaaaaata
    15421 tatcactttt caggttttga ttctggagca caagagataa tgttgaaagt aaatggagga
    15481 aataatcaag cgttatggaa tctaagagaa cagtatattt tagaacaaga aaagaatggt
    15541 caaaaagagt taggaagttt aaaaggtaaa tttgatacat ttgataatgg agaaatcata
    15601 tcaaaagata tgagagtatt gatgagaaat agattagatt tacaagatta ttttaaggaa
    15661 aagaatccat tctgctctgt tggagaaaaa agttattata attggtataa aaataatgta
    15721 tcttttaggc ttgatgatga aactttagat gaaaaaagta aaaaaatttt agaacttgaa
    15781 aatgaactaa atcggctaag aaaaatgata agcccactac aacaaataaa aaaaatcttg
    15841 aaaaaatttt taaagagata ggaggaaaat cttgaataat agagataaaa atattttgtt
    15901 tttgatacat gattacataa aatatgatac tcctatgaat gtaggcggaa cccagttaca
    15961 tatagaagat ttaatttcaa aaatagaaaa tgagacattt tatattttat ataagaaaaa
    16021 aaataaatta atcttagatg aatatagaga ttcaaagtta ataaatacat ataattatta
    16081 ttgtggagat ttatcttcag tagtagaata cacaaatccg ttatttaaac ttatatactc
    16141 tgctatactt gtcaacttca aaatagattt gattcatata catcatttaa aaaatcacac
    16201 atttgatata atatatgaag ctaaaagttt aaacttacca attattatta ctatacatga
    16261 ttattattta gtatgcccta agattaatct gattgataga aataattgtt gttgcgtaaa
    16321 tagagagact aaagaactct gtggagaatg tatgtctgaa gaaataggta tgtcatttga
    16381 agaactacat ttgtatagag aggaagtaag taaaatatta ttgatgtgca atgaggttat
    16441 tataccaaat aaatctgtta gtgaagtact tttaattcac tattattgca taaaagaaaa
    16501 gataagagta atagaacatg gacaaacagg tgaagtatct aaatacgcac ctacatataa
    16561 aaatggaaag tttaatgttg catttgtagg aggattgaaa ccatgtaaag gtagtaaaga
    16621 aattataaaa ataattaaaa attgtactga taaagatatt aatttttttg tatttgggac
    16681 aatagatgat aaagattttg atgatattcc aagtcataat ataaattgta caggaaacta
    16741 ttttagaaaa gatatatata aattattaga agaaaatgaa atacacattg tttgtatatt
    16801 atcaatttgg cctgaaactt tttgttacac tttaagtgaa tcttggcaat gtaatatacc
    16861 tgtgattaca gttgatattg gagctacagg agagagagtg aaaaatggtg gaggtatttt
    16921 aattactgga aataatattg gagaaagtac tctaaaatca attatagagt taaagaatga
    16981 tagaaataaa tatgaaagtt tgtgtaagac agttaaaaac ataaaactac gagatattgg
    17041 agaaatgtct aaagattatt ctaacctata ttttagttat atgaaaaatg ttatgttaga
    17101 taataaaatt tcttcagagc taatattaga tgctttaaaa aatatagatt tatttcaaac
    17161 aaataacagt attaaaaatt atgaacttga agatctaaaa aatgaaatta agtatataaa
    17221 aggtactttt gcctatcgtg tttggcaaaa atacaaggat atgaagatac cttttaagag
    17281 taatatatct agtttcttta aaagaaaagt atctttagaa aaagatatat caaaaaataa
    17341 aaatattata aaaagaaagt ctgaacaatt gaatataata tcaaatattg aatatgaaca
    17401 agtttattat gaaaatgaaa agttaaactt ttatgttgaa ggttggtttt tcagtaaata
    17461 ttatgatatg aatgtatctt gcgaaaattg tgaaagtttt agtatagaaa ggttaagtag
    17521 accagatgta caatctcatt ttggtgggaa aaaagaagct gaaaatagtg gatatagaat
    17581 tgcttttata ggggtagagg aaaatagcaa aatatcactg gtttttgata taggtaattt
    17641 gaagaaatat tataatttta atgttgatac ttcacaggga gttgtatata ttggaaaata
    17701 tcctaaaaaa cttagatgga agagtatacc acaattattt gatatgacag tagtagagcc
    17761 ttataagtat aaaaaggtaa tagataaaaa tagtgaaaca attgaaaatg tttctctgat
    17821 attaaatgca actcgtccaa taaaaaaaga gtgggctgaa gaaaccatta gaagtataat
    17881 aaatcaagga tttaaatcct tatatataat ttcttgtaat gaaaatttaa acttattttc
    17941 agaaatagat aatattatgc tagtgagttc taaattgtta accagaaaag aagagtgttt
    18001 ggagttctta actagtaaat atgattttaa ttgtgagtat gtttctttta tatctattgg
    18061 ggataagatg gaagttaata caattagaga aatgataaag gaagcaaaaa aaagtaatag
    18121 ttttatagta actacaaatg aaaatagatt ttttgaagaa gaatattttg ctccatttta
    18181 caaacaacaa ctttataata gatttgacaa tccatcaata gatagattat gtagaaagag
    18241 tatgttaatt tctactgata aaataattga ttttattagt ggaaatataa aaagtaatga
    18301 gattaagatt attgacaaga tattgtataa ttatagatta tataatgaca acatagataa
    18361 taaagtaaaa gtattggcat attatttacc acaatttcat actattcctg aaaatgatga
    18421 gtggtgggga gagggattta cagaatgggt aaatgtaaat cgtggacgac ctatgttcaa
    18481 aggtcattat caaccacatg ttccagggga gttaggctat tacaatttag taaaagatga
    18541 aggaattcag aagaagcaat ctcagctagc aaatgattat aatatatatg gaatgtgcta
    18601 ttattactat tggtttaatg gtaaaaaatt attggagaaa ccgttagaaa atcttatagc
    18661 tgataagagt ataaatacaa atttttgtat ttgttgggca aatgaaaatt ggtgtagaag
    18721 atgggatgga cttgaaaatg aaatacttat aaaacaagaa cataatgttc agagtgataa
    18781 aagatttatt tatgatgtat taccgatact aaaggatgaa cgttatataa ctatagataa
    18841 caaaccgatt ttactagttt ataagtcaga cttattccca aattttatat caactgttga
    18901 aagttggaat aaaatttgta tagagaatgg tctagagggt ctagaagtaa ttactgttca
    18961 aactggaggt ctagaggatc caagaaacat gggctgtaaa tatgcagttg aatttccacc
    19021 acataatatt tattcaagag tcttatctgc aaaatcaaag gtagaagaat tagataaaga
    19081 ttttgaagga actatattag actatagtga ggttgcaggc ataggaatga ataaaaaagc
    19141 tcagccatat acatttttta gaggtgtaat gctaagttgg gataatacag cacgacgaaa
    19201 tacacaatct cgtatttttt atggctcaaa tccaaatgaa tataaaaaat ggattgcatc
    19261 cgtaattgac ttttcaataa atttttatga agaaaaagaa cgtatgattt ttataaatgc
    19321 atggaatgag tgggctgaag gcacacattt agaaccagat gaaaaatatg gacataaata
    19381 tttagaagtg acaaaggaag ttttaggagc acaatattag tagatacctt taataaatag
    19441 gtttttaaat caaaatatat agttttacta taattagaag ttgtagatta taatctctta
    19501 atacaatttg tatagaaatt gtgttaagag gttatttaca tgctaatcac ctattaatgt
    19561 tttctgagtt aattaaaatt ttcaaggagg tattttattg aataaactaa atagtttaat
    19621 taaaagatta tatcacatgt taccattgag ttatgaaaaa aaaattctgt taaaaaataa
    19681 tgtgtataaa ctattatctc catttataaa aaatacaaat atgtatagca tttggattaa
    19741 tagtttagaa aatccagaaa aatatataaa agataataac ccaaagaagg gtgtagataa
    19801 tgaaaaagat atttatatag ataatttatt taaacgagct tcagagaaat ctagtaacta
    19861 tattgaaata agtgatacaa ggtttcaatt agaaaaaaat gatataaagc tgatatcttt
    19921 ttatttacca cagtttcatc caattgtaga aaatgatgaa tggtggggaa gaggatttac
    19981 agaatggaca aatgtgagta aagcagttcc tcaattttta aatcattatc aaccacatct
    20041 accagcagaa ttgggttttt atgacctgag attaaaagaa gttatgaaga gacaaataga
    20101 gttagcaaaa atgtatggga tatatggttt ttgttttcat cattattggt ttgcaggtaa
    20161 aagactttta gagagaccag taaatatgtt attaaaagat aaagaattag atattccctt
    20221 ttgtctatgt tgggcaaatg aaaattggac aaggcgttgg gatggtttgg aaaatgaagt
    20281 tttaatagaa caaaagcact caaaagaaga cgatttagaa tttattaaag atataagtaa
    20341 ttattttaaa gatgagagat atataaaaat tgatggaaag ccagttttga ttatttatag
    20401 aatagaatta ttaccaaatc caatagaaac aataaaattg tggagaaaat attgcctaga
    20461 aattggctgg aatgatatat tcattgtggg agcacaaaca tttggatttg aagaacacat
    20521 taaatatgga atggatgcag gtgttgaatt tcctcctcat aatataaata attgtcctat
    20581 attaaataag gaaataaatt ttacaaataa aaaatttact ggtttagttt acgattataa
    20641 aaaattagtt gatgataaat tatatataaa aaaatcacat ggaaaggtat ttaaaactgt
    20701 gatgccttct tgggataata cagctagaaa gccaaataat gcaagtatat ttaaaaattc
    20761 tacaccagag ttatataaaa aatggttaaa agatattata tattctacaa aagaaaatgt
    20821 tttagatagt gataacttta tatttataaa tgcttggaat gaatggggag aaggtgcaca
    20881 tcttgaacca gatagaaaat atggctactc atacttaaat gcaacaagag aagctataat
    20941 agagactagg agtgagaaaa ataattaaaa attagttatt taaatagatg tttaaggaga
    21001 gttaaaatat ggataagtta aaaaaaaata ataacctaaa aattaaaata atatttttta
    21061 tattattaca aatatttttt atattttttt tagttgtaaa tttcaaaact cctcttttgg
    21121 gagaagatta tgctttacta tataatggtc catttaaaga tataggtgac tatttttcga
    21181 caattatggc agctcttgaa aagcagatgt caacttggat ggttagaatg ggaaatccat
    21241 taacaataat atggctaagc tttgataaaa gcatatataa catagcagtt tcatttgtat
    21301 caatgatttt cttttttctt atattttttt atggaaatgc aagaaaacca aatgtgaata
    21361 atctgggtga tttaataggt ttttttgttc cagcatcact tatgatgttt ttgagtcctt
    21421 ctatagggga tttgtttttt tggtgcaatg gcagtcttaa ttatttatgg cctctttgta
    21481 tattactttt gtgtgcaatt ccttatagac tttatttatc agagaagaac ataaatatta
    21541 agaatcctat tttgattatt ttatattgta tagcttgctt tatatctggt tttacaaatg
    21601 aaaatactcc accagttatt ataacattag tagctgcatt gataataaga gatttgtatt
    21661 taaaaaagaa accacctaaa tggatagttt tttcctttat atctatttgt gcagggtgga
    21721 taggattagt agtgaattca accaccagat ttagaagtat gtattatagg aatatgtttg
    21781 gcttaccaga acatgctact ataaatgaac ttataaataa tgttttaaga gtaggatatt
    21841 tattcttgaa aagtggattt gcatttgtaa ttatattttt aattttaagt ttgttattta
    21901 tatttatatt aaagtctcaa aaaactgaaa atgagtttaa atataagcat ttgtttgcag
    21961 aaaatatgtt ttttatttta ttaactttta tctctgcagc agcattagtt tttgcaccat
    22021 atacagaact tagatcattt acacttattc atacaatcat attagcaaca ataagtaatt
    22081 tattagtaaa tttatatgaa atatctagtc ataaacaaag acttggactg agtagtatta
    22141 gtataattac tttactttct acttttttac tttttattaa catatacaat gaatataatg
    22201 actattataa atttgatact caacgtactt gtgatataaa gtcacaagta gcagctggga
    22261 aaactacagt atatgcttca aaaaatttta ttgaaaatcg tactatgaat aatagagaat
    22321 tttatatcta cggaaatgat ttaggacaag gtggaaattt ttactcagat tactttggag
    22381 ctaaaaaaat aatctggtat gataaaattg atagtaatat agatccagct actattaatt
    22441 tatcaagtga atctacagat gtgaatgtag aacttataaa tggaaactct gaacaagaca
    22501 atagttctct attatctgat gggattttta atgtttctgg ttgggcaata gataaggtgg
    22561 ctggaaactc tccaagtaaa gtatttataa aaatagacga taagtattat caagctagaa
    22621 cagtaatacg tgaagatgtt gctaaatatt ttgacaataa aaagtataaa aaagcagggt
    22681 ttgagtgttc tataccaact aaagatataa aaaaagggaa gcataaagtg acactttgtg
    22741 tcataagtaa tgatggagaa aaaagatatg aagtagattc aggaaaatct atagaattta
    22801 aataaaagct ataaaatgga aaggaggaca tgtaaatggc aagtttaatt aaacaaagaa
    22861 aatataatag aaatatatta ttagaatata ttaaattaat gagaccaaaa caatatatca
    22921 aaaacggatt tgttttagct gcattaatat tttcaaacaa tatactcaat ccatcattag
    22981 cgttaaaatc tatattatct tttatagcat tttgtatgat atcatcatca gcctatatac
    23041 taaatgatat tttagatata gaaaaagata agatgcatcc taaaaagtgc aagagacctc
    23101 tagctagtgg atcaattgga aagaaggggg caatttcatt aggtattgta ttagttttat
    23161 cttcaatttt attatcctta ttaatacata aaaatctatg tgtaataata ttattgtact
    23221 tatttaacaa tattatgtat tcactcaaat taaaaaatat aatattaata gacgtatttt
    23281 ctatagccat aggattcata ctgagagttt gtgctgggtc tatagcaata aatgttagtt
    23341 tatcaagttg gataatttta tgcacattct ttttatcttt atatttaggt tttgggaagc
    23401 gaaaaaaaga aataatatta cttaaagaag atgc
//
LOCUS       DAEPKC010000059        23277 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.059, whole genome shotgun sequence.
ACCESSION   DAEPKC010000059 DAEPKC010000000
VERSION     DAEPKC010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 23277)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23277)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23277
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.059"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            115..861
                     /gene="cdtR"
                     /locus_tag="KR294_002351"
     CDS             115..861
                     /gene="cdtR"
                     /locus_tag="KR294_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family response regulator CdtR"
                     /protein_id="HBH0240423.1"
                     /translation="MDILIFDNDVCFGMKLKEKINNILIKEGFDNDVVRLYHNANLLL
                     KELTEKNKVRIYFIVVDAKYKISNELCDGLWIAQKIRESDYISPIIFLTNHIEMILGI
                     FDYRLEVMDFILKHDMEIAESKIKACIKIAHKRYIKEKNYRSNFFTIYSDFSLWKISF
                     DEVIYFETSTIPHKIKLVTTSRIFEFYKSLKSLPDLDACFIRVHKSFVVNKYHIVSLD
                     LKKNNIKMSNGHICRISNTYRNILKNIIKT"
     gene            1250..1432
                     /locus_tag="KR294_002352"
     CDS             1250..1432
                     /locus_tag="KR294_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240424.1"
                     /translation="MKKFRKHKSISNCISILLILYLTLGSLLPNNIYAQDLQSYSGKV
                     CNTTYKAPIERSEGFF"
     gene            1768..3335
                     /locus_tag="KR294_002353"
                     /pseudo
     CDS             1768..3335
                     /locus_tag="KR294_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021426623.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iota toxin protein Ib"
     gene            complement(3987..4988)
                     /gene="trpS"
                     /locus_tag="KR294_002354"
     CDS             complement(3987..4988)
                     /gene="trpS"
                     /locus_tag="KR294_002354"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HBH0240425.1"
                     /translation="MSEKKVILSGAQPSGKMTLGNYLGAIKNWTELQDNYDCYYSIVD
                     LHAITVPQDPKVLRANTIELLAQYIACGLDPEKNTIFIQSHVKEHVELMWVLNTMTYM
                     GELSRMTQFKDKSQKSEANLNAGLFTYPVLMAADILLYQTDLVPVGDDQKQHLELARD
                     LANRFNNRFSPTFVVPEGYYPKGGARVMSLQEPTKKMSKSDSNENAFILLADDSDSIK
                     RKIKRSVTDSLGVVKYNDEQPGIKNLIDIYSNLSKKSVEEIVNMYEGKGYGIFKEDVA
                     EVVSEALRPIREKYVDLLNNKDYLEKIYSMGAEKAEKQARKTLRKVYKKVGFIERRY"
     gene            complement(5011..5709)
                     /locus_tag="KR294_002355"
     CDS             complement(5011..5709)
                     /locus_tag="KR294_002355"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HBH0240426.1"
                     /translation="MNVIGIIGAMDEEVSILVDLMDIRETIKKASLEFYKGILEGKNV
                     VLVKCGIGKVNSALCAQILISEFKVDAIVNTGVAGALNEKLDVNDIVISTDAIQYDVD
                     TTAFGDPKGVIPRMKTSVFKADERLIDAAYKSSVEEVKTHKVLKGRVVTGDKFINSKE
                     LKEELVNDFGGYCGEMEGGAIAHVCYLNNTPFVIIRAMSDKADGSADVTYDVFVHDAA
                     NNSKDIVLNMLKSI"
     misc_binding    complement(5752..5992)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(6083..7486)
                     /locus_tag="KR294_002356"
     CDS             complement(6083..7486)
                     /locus_tag="KR294_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBH0240427.1"
                     /translation="MEKKKIGLWSLVFMNVSALYGIRWIAKSTASSFGLGLGAIPMWL
                     LFSFIYFVPGALICAELASTYQKGDGGLYDWVKEAFGEKYGFLVSWLNWTAKIFWYSS
                     FLTFLAVNVSYTIGNPALADNKMFVLILSLIIFWALSLIATKGISFTKIFTNTGALGS
                     TIPSAILIIFSFVAVFVLKKHDIASTYTIASMTPKLNMDAFVAISAIMFGLAGAETAA
                     NFITEIDKPEKNFPKAILISAGIVASLYVLGSIAITMIIPPDQITASKGVLDALSAVC
                     ASLGIGSWLVQLIAFGIAFSVLGAIVLYIASPIKMLFGSVKKGIFPDSLVEVNEHKIP
                     SKAVILQAIIVTIILLVTTLMPSVDAIYNVLVTMTALTALFPYVLLYASYIKLRKERP
                     DEIRPYTMAKSTSTCLGLAKMVLVVTVVGILLSAAPVMPTFAENVIYEIEMIGGGLLV
                     ILSGLWLWNRYEKKTAK"
     gene            7983..9059
                     /locus_tag="KR294_002357"
     CDS             7983..9059
                     /locus_tag="KR294_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBH0240428.1"
                     /translation="MKAQRLNAVLEQMKKDDISQMLVSDPTSIFYLTGVLIHPGERLL
                     ALYLNLNGNNKLFINELFPVSEDLGVEMVWFNDTQNPVEIITEHIDKNATMGVDKNWP
                     ARFLLNLIELGGGSKFVNSSYIIDTLRMCKDEEEKELMRIASKLNDKAMEQLKATVSG
                     ELTEKQLVGKLSKIYEDLGTDGFSFDPIIGFGPNGANPHGEPGNALVKPGDAIILDIG
                     CIKDNYCADMTRTVFYKEIPEKGREIFEIVLEANKRAEAIVKPGVRFCDIDAAARDYI
                     TEKGYGQYFTHRTGHSIGLEVHDKGDVSSINTDTVQPGMIFSIEPGIYLPGEFGVRIE
                     DLVLVTEDGCEILNKHDKEICVVG"
     gene            complement(9176..10018)
                     /locus_tag="KR294_002358"
     CDS             complement(9176..10018)
                     /locus_tag="KR294_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBH0240429.1"
                     /translation="MDKIKLIVDSACDLPDDIIEKYNIEVVGLNVSFGEESYISGKEI
                     DNETFYRKMSESKVLPKTSCPSPDKFLEAYHCQEESVLVINISSGLSGTYNSALLAKD
                     MFEKEGNNKKVEVIDSLSGSIGIGQLVLKAAILIKEGKEIEEIVSIINKYKDNPPFFG
                     TLETLENAIKGGRINPIAGKIINTLNFKAIIQVADGVVTPIDKARGEGNSLKKLITLV
                     ESKIKDKEEKVLFIGHANCPEKAQKVREVMEKDVKYKDVVICEVGSVMGTYTSKGAIL
                     ITAI"
     gene            10202..10774
                     /locus_tag="KR294_002359"
     CDS             10202..10774
                     /locus_tag="KR294_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH0240430.1"
                     /translation="MKTNNMKQAILSSATNLIAKNGVQNTSLADIAKDVNISKGTLYY
                     HYASKDDIIYDIADTHLEVITSAILNCVKNVKSKNSQIEMVNLILEKISTIESRGRVH
                     MYLICEAITSNNDLKERIRLKYIEWRTTLKSEIVESLEKYNSSENEQDAESFSFLLMS
                     IVDGLVVQSLLKTEKIPYENIASFLVNHWI"
     gene            complement(10937..11209)
                     /locus_tag="KR294_002360"
     CDS             complement(10937..11209)
                     /locus_tag="KR294_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240431.1"
                     /translation="MLRERFVVRNHHNPHTSGCCGTGGEGCCGGDNHEHSHQHSHSHG
                     HEHEHVNGVGHDHNHDDGFSGTHEHSHEHTHTHGHEHSDGHTHEHK"
     gene            complement(11336..12208)
                     /locus_tag="KR294_002361"
     CDS             complement(11336..12208)
                     /locus_tag="KR294_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBH0240432.1"
                     /translation="MYGESKKLSIDNNIFLQYCLIILGMILSTLGINLYLAPAKLLSG
                     GVAGICVILYKLFGINQGISSFLMNIPIFIIARKYFDNKFLLISFVNMLLFSLALGLT
                     QDIAKYFPIDDTMLQCIYGGALTGIGMGLTFKARATAGGLDIIAAIMKRKYDIPMKNT
                     FLFINFFVVCAGAFLFGAKLVMYTLITMYIISFTMDIGKDCFDRKKSILLISNKYDEI
                     SKVIMNKMGRGVTFLEAEGAYTQNKKKMIYCIISANEIGKFKDLIYDMDSEAFISVNN
                     VEEVKGGGFKDKFL"
     gene            complement(12495..15602)
                     /locus_tag="KR294_002362"
     CDS             complement(12495..15602)
                     /locus_tag="KR294_002362"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HBH0240433.1"
                     /translation="MAKFKPLVDSSVKQAEAQVFDYWKDINILEKTLEKGKDDPSFVF
                     YEGPPTANGNPGVHHVLSRTLKDSVCRYKTMSGYQVKRKAGWDTHGLPVEIQVEKELG
                     LTSKQQIEEYGIAEFNQKCRESVFSFEKQWRIMTERMAYEVDLDNPYITLDNNYIESV
                     WWILNKFNKEGYIYEGHKILPYCPRCGTGLASHEVAQGYKEVKTNTVIAKFKKKDADE
                     YFLAWTTTPWTLPSNVSLTVNADVDYLKVKKGDEVYYVSKPLADKVLGEDYEVLEEMK
                     GKDLEGLEYEQLMPFVEVDKKAFFITVGDYVTTEDGTGIVHTAPAFGEDDYNTGKRYD
                     LPVIQPVDETGKFTSTPWEGRFVMEDGLDVEIIKWLASENKLYSKEKVVHNYPHCWRC
                     QTPLVYYAKPSWYIEMTKLKDKLIENNNGVKWFPSFVGEKRFGNWLENLNDWAISRTR
                     YWGTPLPIWRCECGHTDSVGSRAELAEKAIEDVNPETVELHRPYVDDIHLKCEKCGKP
                     MTRVTEVIDCWFDSGAMPFAQHHYPFENKENFDQLFPADYISEGIDQTRGWFYSLLAV
                     STFVLGKAPYKSVLVPDLVLDKDGKKMSKSRGNTVNPMELFDQYGADALRWYLLYVSP
                     PWTPTKFDMDGLKEIQSKFIGTMKNVYNFFTLYANTDDINPTEFFVEYKDRPELDRWI
                     LSKFNNLMKDVEENLAIFELNKTLRMIQDFINDDLSNWYIRRSRRRFWATELTEDKKA
                     VYNTTYELLHGLCRAIAPFAPYMSEEMYRNLTGEVSVHLAEYPKCNEELVDTKLEEKM
                     DLAKNLVTLGRASREVERIKVRQPLQKVLVDGKFEDTISDVVDLIKEELNVKEVIFAK
                     DLDEYMNFSLKPNFKEAGPLLGSKMNLFVGALSKLNAHETANKLEKGETLTVDLDGEA
                     FEFNKDLVLIGITAKEGFNVSVENNLFVILDTKLTEELINEGYAREFISKVQQLRKSN
                     NFEVLDNIVIEYCGDDEIAKAVDHFNEYIKSETLALEINRVDDKSLEEQNLNDHMTGI
                     KVIKK"
     misc_binding    complement(15695..15927)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(16102..16629)
                     /locus_tag="KR294_002363"
     CDS             complement(16102..16629)
                     /locus_tag="KR294_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HBH0240434.1"
                     /translation="MLTPIEIENKEFKKGLRGYRDEEVDEFLDIIKEDYESLCRENTA
                     LKEKLGLYQDQVNKYENIEETLKATLITAQSAAEDTCSAANKKAKIIVEEADLKARQI
                     IEQANNRVIEIRKEYDALVKEFKIFRNKFKSLLEDEIRSVDEIFYDVDEKCVNAFEGT
                     TVYNYSNDEAATTLE"
     gene            complement(16664..17449)
                     /locus_tag="KR294_002364"
     CDS             complement(16664..17449)
                     /locus_tag="KR294_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HBH0240435.1"
                     /translation="MDKLKLTNHIKDIDLKNKMFKVIDKANSCIKNYDVKSTEFLNPY
                     EVKNAVAILNSTNEIKYSVDGGYEQAERSTVFIYPFYMEYEDIEDTLRFLQIEGNFKF
                     KNISHKDYLGSILGLGIKREKIGDIIIHDSFCQVVVSSDICDFIIVNLEKVSRNNVIV
                     KEISRENIVNSSSKYKEVSFTVSSDRLDCVISGIYNISRQDSAKYINGEKVHVNYEKI
                     TSTSKIVKNDDLISIRGKGRAKVTQIGDITKKGKIKVQARLIV"
     gene            complement(17459..17716)
                     /locus_tag="KR294_002365"
     CDS             complement(17459..17716)
                     /locus_tag="KR294_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HBH0240436.1"
                     /translation="MGTIRIALYYLLDIIAWMIVIKSLMTWFPNGRQSKIFDILENLT
                     EPIEGPIRSIMYKYTNGPIDFSPLIAIVLLMFLRQLVLVIF"
     gene            complement(17735..18193)
                     /locus_tag="KR294_002366"
     CDS             complement(17735..18193)
                     /locus_tag="KR294_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HBH0240437.1"
                     /translation="MSNGIISKFKNWIVDEEEDYIEDEYESGMDDIVQEEEMNSGFST
                     AKANKIVNLHTTSQMKVVIVEPKVYDEAATIADHLKQRRAVIVNLEGLTNSEVRKSIF
                     NFMNGAVYVLDGSIQKVSKSIFILAPNNVDIDANMKKELESKAFFPWQNK"
     gene            complement(18233..18937)
                     /locus_tag="KR294_002367"
     CDS             complement(18233..18937)
                     /locus_tag="KR294_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HBH0240438.1"
                     /translation="MGSIKDNLSEIRNKIDKAAKKVDRDSKEITLLAVTKTVDVDLVN
                     EAMREGITSVGENKPQELARKYDIIGDKLNWHLIGTLQTNKVKYIIDKVCMIHSLDRI
                     ALCEEIQKRAEQINREIDCLVQVNISKEESKHGLDREEVVDFVKEVSEKYKNIKIKGL
                     MTMAPFIEDEDEIRGVFKGLKDLSKQIKELNIPNVGMDVLSMGMSHDYEIAIEEGATI
                     VRVGTSIFGERNYNKK"
     gene            complement(18947..19582)
                     /locus_tag="KR294_002368"
     CDS             complement(18947..19582)
                     /locus_tag="KR294_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240439.1"
                     /translation="MKKVKYTRLVILGILIYLVFNILVMIISKNVDTLVLKNEKVDAK
                     IHVKGTIEKDANDQSNYLSTYISKEDSNNFEKNQNVIIEYHEQKLDAKVYKIYENNNK
                     IMVKLKISNQIVANQDTSVEEFDIIYNQMECLKIPKTSIKTKDNKRGVYVIDEQSQSV
                     KFVILEGITYENESSVFVDYYKNDINGVTSVNLYDKIILRPNSINTNIRIK"
     gene            19963..21003
                     /locus_tag="KR294_002369"
     CDS             19963..21003
                     /locus_tag="KR294_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH0240440.1"
                     /translation="MSEILLGTGLLLLVLCCFTIFSYKAPYGMKAMGALANAACATFL
                     VEAFNLSLLGDVLGMEFFRSVGAANGSLGGVAAAILVPLALGVSPVYAVLIGLSCLDF
                     SILSGFVAGYFVSFLIKFIEKKVPPGVDLVVVILLCAPLSRLIASNVDPLVNSTLLQI
                     GQVLIEATNISPIIMGIILGGLITVVGTSPLSSMALTSIIGLTGLPMAIGALGAFGSA
                     FMNSTLFAKLKLGSKKDIISVAIEPLTQSDIISANPIPIYSTNFFGGAFSGIIVALMG
                     LVNMTPGTATPVAGFAIMFAYNPVQQVLITAGLCALFNVIAGFLGSKIFSTFKVLTAG
                     EIRGTDVEEEIA"
     gene            complement(21466..22821)
                     /locus_tag="KR294_002370"
     CDS             complement(21466..22821)
                     /locus_tag="KR294_002370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009170073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HBH0240441.1"
                     /translation="MNVGNILETIKMIDEEQLDIRTITMGISLLDCIDPDGDKAREKI
                     YNKIMSSAKDLVKVGKDIEREFGIPIVNKRVSVTPISIIAGATDENDYVKFAQTLDKA
                     AEDLGIDFIGGFSALVQKGYTKGDKILIKSIPKALASTNKVCASVNVGSTRCGINMDA
                     VKEMGEIIKETAELTKDAKGFGCAKLVVFCNAVEDNPFMAGAFHGVGEADRIINVGVS
                     GPGVVKRALEKVKGEPFDVVSETVKKTAFKITRVGQLVAKEASSRLDVPFGIIDLSLA
                     PTPAIGDSVANILEEMGLEVVGTHGTTAALALLNDAVKKGGVMACSHVGGLSGAFIPV
                     SEDAGMIDAVIKGALSIDKLEAMTAICSVGLDMIAVPGNTTAGTLGAMIADEAAIGMI
                     NNKTTAVRIIPAPGCDVGDMVEFGGLLGRAPVMPINTNSSELFTQRGGRIPAPIHSFK
                     N"
     gene            complement(22847..23116)
                     /locus_tag="KR294_002371"
     CDS             complement(22847..23116)
                     /locus_tag="KR294_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010963800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HBH0240442.1"
                     /translation="MKAILTVIGKDKPGIVAGISDELYKQNINIVDISQKILQDYFTM
                     IMIVDLEKSLNSFEKTVEDLVERGKKLSVDVKIQREEIFNSMHNL"
BASE COUNT         7859 a         3827 c         2712 g         8879 t
ORIGIN      
        1 tataccttaa ttctaactat ccttaatctt atttatctcc tagtgttatt ttatgtattt
       61 tctataaaat acttttgttt ttttactttt gaatttttta taggagggta tttagtggat
      121 atattaatct ttgataatga tgtttgtttt ggaatgaaac taaaagaaaa aataaataat
      181 attttaataa aagaaggttt tgataatgat gttgtaagat tatatcataa tgcaaatttg
      241 ttattaaaag agcttactga aaaaaataaa gtaagaatat attttatagt tgtagacgca
      301 aaatataaga taagtaatga attatgtgat ggattatgga tagcacaaaa aattagagaa
      361 tcagattata ttagtccaat catatttctt acaaatcata tagaaatgat tttagggatc
      421 ttcgattata ggttagaagt tatggacttt atactaaaac atgatatgga aattgctgaa
      481 agtaaaataa aagcttgtat taaaattgct cacaaaagat acattaaaga aaaaaattat
      541 cgctctaatt tttttactat ctattcagat ttctcactat ggaaaatttc atttgatgaa
      601 gttatatatt ttgaaacaag cactattcca cataaaataa aattagtgac tacttctaga
      661 atatttgaat tctataaaag tttaaagtct ttaccagatt tagatgcatg ctttatccgt
      721 gtacataaat cttttgtagt taataaatat catattgttt ctctcgacct aaagaaaaat
      781 aatattaaaa tgagtaatgg ccatatatgt cgtatatcta atacatatag aaatatttta
      841 aagaatatta ttaaaacata ataaatagaa aaaggagatg tctcaagata aaaatttgaa
      901 ccatctcttt tttatacaaa aagagtaatc cctaagaatc ctctatataa taatcatatt
      961 gtgaaaaaac acatactgac tatatcatat ataactacta ttagatatta taacaattgt
     1021 tcctagatta tgattcgata agatagctca ttaaatcata aaagtacgaa atagtctctt
     1081 taaaatattc agttgttatt ttgtactgac atatcatata aatacatatt tttatgatat
     1141 atacctacat attttatgaa atttatataa aaaattctta tttagattat ataatctaaa
     1201 taaattaaaa ttcaaaagtt aactaaacta atatttgtag ggagaataaa tgaaaaaatt
     1261 taggaaacat aaaagtatta gtaattgtat atctatattg ttgatattat atctaacttt
     1321 aggtagtttg ttacctaata acatttatgc acaagattta caaagctata gtggaaaagt
     1381 ttgtaatact acttacaagg ctcctataga aagatcagaa ggattttttt aaagataaag
     1441 aaaaggctaa agaatgagaa agaaaagatc aaaaacttga aaaatctgaa aaagaagtat
     1501 taggatcata taaaaaagat tctatagaga taagcaaata ttctcagaca agaaattatt
     1561 tttatgatta tcaaatagaa gcaaattctt gagaaaaaga atatagagaa cttcgaaatg
     1621 ctatatcaaa aaataaaata gataaaccta tgtatgtata ttattttgaa tctccagaaa
     1681 aatttgcatt taataaagta ataagaacaa aaaatcaaaa cgaaatttca ttagaaaaat
     1741 ttaatgagtt taaagaaact atacaagaca aattattacc atacaacaga taattcaact
     1801 gctgttcaaa atagcaatgg ataatcatga aatactggat taagtataaa caaaggagaa
     1861 tctgcatata taaatgcaaa tattagatac tacaacacag gtactgcacc tatgtacaaa
     1921 gtgacaccaa caacaaattt agtgttagat ggagatgcat tatcaactat caaagcacaa
     1981 gaaaatcaaa ttggcaataa tctatctcct ggaaatactt atctcaaaaa aggattttca
     2041 cctatggctc ttaacacaat gtatcaattt agttctagac tgattcctat aaattataat
     2101 taattaaaaa aattagatga tggaaagcaa attaaattag aaacaacaca agtaagtgga
     2161 aattttggta caaaaaatgg ttctggacaa atagtaacag aatgaaatag ttggtaagac
     2221 gatataggtc aaattgacag tatttctgta tctattatat tagatacaga aaatgaatct
     2281 tacaaaagaa gaattactgc taaaagttta caggtcccag aagataaaac acctgaactt
     2341 acaattggag aagcaattga aaaaactttt ggcactacta aaaaagatgg tttgttatat
     2401 tttaataata taccaataga tgaaagttgt gttgaactca tatttgatga taatataggc
     2461 aataagatta aagacagttt aaaaactttg tctgataaac aaatatgtaa tgttaaactt
     2521 gaaagaggaa tgaatatact tataaaaaca ccaacttact ttactaattt tgatgattac
     2581 aataattacc ctagtatatg gagtaatgtt aatactacaa atcaagatgg tttaaaaggc
     2641 tcagcaaata gattaaatgg tgagacgaag attaaaatac ctatgtctga actaaaacct
     2701 tataaacgtt atgtttttag taaaattcaa aaaatccttt aacatataat tcaataattg
     2761 taaatataaa agtaaaagaa gaaaaaacgg attatttggt actagaacaa ggatatacaa
     2821 aatttagtta tgaatttgaa actactgaaa aagattcttc taatataaat atagcattaa
     2881 ttgatagtga tacaatatac ttagataact tatctattac agagctaaat agtactcctg
     2941 aaatacttga tgaaccagaa gttaaaattc caactgttca agaaataata gttacacata
     3001 aaatatattc tgcagatttt aaatttaatc caagtacaat aaaggcttat ataaatggta
     3061 tgtattttac accaacataa actaataaag aagctctcga ttatgtccaa aaatatagag
     3121 ttgaagctac tttacaatat tttggattta aagatattga aactaaagat aaagaattgc
     3181 gtaattattt aggagataca aatcaaccta aaactgattg tgttaatctt aggagttatt
     3241 ttacaggtgg agaaaatatt atgacataca agaaattaag aatatataca attactcaag
     3301 atgatagaga gttattggtt cttagtgttg attagtatca aatgatttaa atttatcccc
     3361 acaatacaat atgtatttac cttataaagt attaaaaaat taactttata aggtattttt
     3421 tatttaaata ttatcttctt ctaatatatt cttttttaga actatattgt attaaaaaga
     3481 taattatctg tatcatatca cctatatata aacataaatt catttaatta tataaattta
     3541 aaaaatattt ttttgatata ttattgacaa ttttcattat aagagttaaa attaactcat
     3601 aaattacata ttgggtataa aatacaatgt atgttagaag ttgtttcaga aggctatggt
     3661 tttctgattt ttttatgctc agtagtgata tgcaaaaaag acaaagttga catcagttaa
     3721 cttttacctt tattctactt tccccaaagt aagaataatc taaccccttt gagatgagca
     3781 aaagctcatc tttttttatt atcaaaagat gctgtctcaa aatagagata atcctctttt
     3841 tcattgttga aatgattaaa atatatttta tttcatacaa aaaagagtgc ctcatgaaca
     3901 aaagttcact ttgagactct ctctttcata tcatatacct ttttaataac tttaaaattt
     3961 atttatcaag taaagatagc taataattag tatcttctct ctataaatcc aactttttta
     4021 taaacttttc taagagtttt tctagcttgt ttttcggctt tttctgctcc catactatat
     4081 attttttcta aataatcttt attattaaga aggtcaacat atttttctct tataggtctt
     4141 aaagcttctg atactacttc agccacatct tctttaaata tgccataacc ctttccttca
     4201 tacatgttta caatctcttc tacactcttt ttacttaaat tagaatatat atcaattagg
     4261 tttttaatac ctggttgttc atcattgtat tttacaacac ctaaagaatc agtaacactt
     4321 ctttttatct ttctctttat agaatctgaa tcatctgcta atagtataaa tgcattttca
     4381 tttgaatcgg atttactcat ttttttagtt ggctcttgca aactcatcac tcttgctcca
     4441 ccttttgggt agtatccttc tggaactaca aaagtaggtg aaaatctatt attaaaccta
     4501 tttgctaaat cacgagctaa ttctaaatgt tgtttttggt catctccaac tggaactagg
     4561 tcagtttgat acaacaatat gtcagcagcc ataagaactg gatatgtgaa taaacctgca
     4621 tttagatttg cttcactctt ttgtgattta tctttgaatt gagtcattct acttaattca
     4681 cccatataag tcatagtatt caatacccac ataagttcaa catgctcttt gacatgtgat
     4741 tgtataaata tagtattttt ttctgggtct aatccacaag ctatatattg agcaagtaat
     4801 tctatagtat tggctcttaa aactttaggg tcttgaggta ctgttattgc atgcaaatca
     4861 actatactat aataacaatc ataattgtct tgaagttcag tccagttttt tatagctcct
     4921 aaataatttc ctaaagtcat tttgcctgat ggctgtgcac cacttaatat aacttttttt
     4981 tcactcattt ttttgtacct ccttatatat ttatattgat tttaacatat ttaaaactat
     5041 gtctttagag ttattggcag catcatgtac aaatacatca taagtaacat cagcacttcc
     5101 atctgcctta tcagacattg ctcttattat tacaaatgga gtattattta aatagcatac
     5161 atgagctata gctccacctt ccatttctcc acaatatcca ccaaaatcat ttactaattc
     5221 ttcttttaat tctttagaat ttataaattt atctcctgta actactcttc cttttaatac
     5281 tttatgagtc tttacttctt ccacagaaga tttgtaagca gcatctataa gtctttcatc
     5341 tgctttaaat acagaagtct tcattcttgg tataactccc ttagggtctc caaatgctgt
     5401 agtgtctaca tcatactgta tagcatcagt tgatattact atatcattaa catcaagttt
     5461 ttcgtttaaa gctcctgcaa cacctgtatt aacaatagca tcaaccttaa attcgcttat
     5521 tagtatctgg gcacaaagag cagagttaac cttacctatg ccacacttta ctaacactac
     5581 attcttacct tccaaaattc ccttataaaa ttctaagcta gcttttttta tagtctctct
     5641 aatatccatt aaatcaacta aaatactaac ttcttcatcc attgcaccta taattcctat
     5701 tacgttcatt tttcctccta aattttctat attaaaaaat ccgtcctaaa tcaataggac
     5761 ggatatattt tccgtggtac cacctaaatt tatatacact caaaattgaa tatatatatc
     5821 ttaatatatg ctataacgtg catacacgat atcaaatact ctgtaatctt aaattacatt
     5881 tcattttact cctcaaagac ccattcaata aatacttttt attaagttct cagcatcctt
     5941 aattctctgt gcaaaaatat atttatttac tatttcttat ctcaggattt aatttattaa
     6001 tttctttatt ttataatatt ccttacacta taaattgtca actatatatt ataatatcca
     6061 aaagaaattt ttaaaataca ttttatttag ctgttttctt ttcatatcta ttccataacc
     6121 atagaccaga taatataact agaagacctc caccaatcat ctctatctca tatataacat
     6181 tttcagcaaa tgtaggcata actggtgctg cagataataa tatacccact acagttacaa
     6241 ctaaaaccat ttttgctaaa cctaggcaag tacttgttga ttttgccata gtataaggtc
     6301 taatttcatc tggtctctct tttcttagtt taatataaga agcatataac aatacatatg
     6361 ggaataatgc agttaatgct gtcatagtta caagaacatt gtatatagca tcaacagaag
     6421 gcattaatgt agtcaccaat agtattatag taactattat tgcttgaagt ataactgctt
     6481 tagaaggtat cttgtgttca tttacctcta ctaaactatc tggaaatatt ccttttttaa
     6541 cactaccaaa taacattttt attggtgatg ctatgtaaag aactattgct cctaatactg
     6601 aaaaagctat accaaaagct attaattgaa ccaaccaaga accaattcct aaagacgcac
     6661 aaacagcaga aagtgcatct aatacacctt tagaagcagt aatttggtct ggtggtatta
     6721 tcattgttat tgcaattgaa cctaatacat ataatgaagc tactattcca gctgatatta
     6781 atattgcctt agggaagttc ttttcaggct tatctatttc tgttatgaag ttagcagcag
     6841 tctctgctcc tgctaaacca aacattatag ctgatatagc aacaaatgca tccatattaa
     6901 gttttggagt cattgaagct attgtgtatg tagaagctat atcatgtttt ttcaatacaa
     6961 atactgctac aaatgaaaat attataagta tagcacttgg tattgttgaa cctaatgcac
     7021 ctgtattagt aaatattttt gtaaaactta ttcctttagt tgctataaga gataatgccc
     7081 agaatattat taaagataat ataagtacaa acatcttatt atcagcaagg gctggatttc
     7141 ctattgtata agaaacattt actgctaaga aagttaaaaa tgaagaatac caaaatattt
     7201 tagctgtcca gtttaaccaa gaaactaaaa atccatactt ttctccaaag gcttccttaa
     7261 cccaatcgta aagacctcca tcaccttttt gatatgtaga agctaattca gcacaaatta
     7321 aagctcctgg tacaaagtat ataaatgaga ataataacca cataggtatt gcacctaatc
     7381 ctaaaccaaa gcttgatgct gtagatttag ctatccatct tataccatat aaagctgata
     7441 cattcataaa taccaaactc cataggccta tttttttctt ttccatccta atttaatttc
     7501 ccctctctat taattatttt aaatttaatt tcaaaattaa taaaatagat tcattattat
     7561 taaactgata tttttcaaaa tatttgcata ttcaaaaaca gttttaataa taaaccttaa
     7621 atactttgaa atcaaatctt attaaaaatg ataaatttaa aagttttacc actttaattc
     7681 taatgatact aaatttttaa aattgtttca atattatttt attataaaat tttatttatt
     7741 atttttcatt agtatataaa aagataaaat acataacttt atagacttaa tttattactt
     7801 ttatagaatt ttcacaataa aaagtcattt tacttccgta tttaatgcaa aagtagagat
     7861 taaacttaat ataaaaaata tataacaaat tttttttata tttctagaag aaaagtatac
     7921 tcttttttgt ttaataatgc taaaattgat ttgtattgaa ttttgattag gaggaaatta
     7981 ttatgaaagc tcaaagatta aatgctgtac ttgaacaaat gaaaaaagat gatatttctc
     8041 aaatgttagt aagtgaccct acttctatat tttatcttac aggagtacta atccatccag
     8101 gcgaaagact attagcatta tacttaaatt taaatggcaa taataaatta tttataaatg
     8161 aattattccc agtttcagaa gatttaggtg ttgaaatggt ttggttcaat gatactcaaa
     8221 atccagtaga aataataact gaacatatag acaaaaatgc tactatgggt gttgataaaa
     8281 actggccagc tagattctta ttaaacttaa tagaattagg tggaggaagt aagtttgtaa
     8341 attcatctta tataatagat actttaagaa tgtgtaaaga tgaagaagaa aaagagttaa
     8401 tgagaatagc ttcaaaatta aatgacaagg ctatggaaca acttaaagct actgtttctg
     8461 gtgaacttac agaaaaacaa cttgttggta aattatctaa aatatatgaa gacctaggta
     8521 ctgatggatt ttcatttgac cctattatag gttttggacc taatggagct aatccacatg
     8581 gtgaacctgg aaatgcactt gtgaaaccag gagatgcaat aatcttagat ataggttgta
     8641 taaaagataa ctattgtgct gatatgacaa gaactgtatt ctataaagaa atacctgaaa
     8701 aaggtagaga aatatttgaa atagttcttg aagctaataa gagagctgaa gctattgtaa
     8761 aaccaggtgt tagattctgt gatatagatg ctgctgctcg tgactacata actgaaaagg
     8821 gatatggaca gtacttcact catagaactg gtcactctat aggacttgaa gttcatgata
     8881 aaggagatgt atcttctata aatacagata ctgtacaacc aggaatgata ttctctatag
     8941 agccaggtat atatttacca ggtgagttcg gagttagaat agaagattta gtacttgtta
     9001 ctgaagatgg ttgtgagata ttaaacaaac atgacaaaga aatatgtgta gttggttaat
     9061 tctaaaatca atttgataaa attaaaaagc catataaaaa tgttttaaac atttttatat
     9121 ggctttaatt tctcaatcta tgatttattt caatccatta tttatattgc agtatttata
     9181 ttgcagttat taagattgca ccctttgaag tatatgtccc catcactgaa ccaacttcac
     9241 agattacaac atctttgtat tttacatcct tttccataac ttcccttacc ttttgagcct
     9301 tttctgggca attagcatgt cctataaata aaaccttttc ttctttatct ttaatttttg
     9361 actctactaa agtaatcagc tttttcaaac tgtttccttc acctcttgcc ttatctatag
     9421 gagttacaac gccatctgca acttgtatta tcgccttaaa atttaaggta tttataattt
     9481 ttcctgctat tggatttatt ctaccaccct taatagcatt ttctaaagtt tcaagtgttc
     9541 caaaaaatgg aggattatct ttatatttat ttattattga aacaatctct tcaatttctt
     9601 ttccttcttt tattaatatt gctgctttta acactaattg tcctattcca attgacccac
     9661 taagtgaatc tataacctca actttcttgt tatttccttc cttttcaaac atatcttttg
     9721 ctaaaagtgc actattataa gtcccagata atcctgaact tatattaatc actaatacac
     9781 tttcttcctg acaatggtat gcttctaaaa atttatcagg agaaggacat gatgtttttg
     9841 gtagtacttt actctcactc atttttctat agaaagtttc attatctatt tcctttccag
     9901 atatataact ttcttctcca aaagatacat ttaaaccaac aacttctatg ttgtattttt
     9961 ctattatatc atcaggtaag tcacatgcac tgtccactat caattttatt ttatccatat
    10021 taacctcact ataagatatt attttattta ttcagtcggt cgtacgaccg atttaattat
    10081 tattttatat attgaatgaa aaaaagtcaa tagatataga ttctcgcttt attgacaata
    10141 aatatccata agcttataat gttattaatt tgttataaat atacatggaa aggtaggttt
    10201 tatgaaaaca aataatatga aacaggctat tttatcatct gcaaccaatt taatagccaa
    10261 aaatggagtt caaaatacta gccttgctga tattgcaaaa gatgtaaata taagtaaagg
    10321 tactttgtat tatcactacg catctaaaga tgatattata tatgatattg cggatactca
    10381 tttagaagtt ataactagtg ctatactaaa ctgtgtaaaa aatgtcaaat caaaaaattc
    10441 tcaaatagaa atggttaact taatcttaga gaaaatatct actatagaaa gtcgtggtag
    10501 ggtacatatg tatcttattt gtgaggcaat tacttcaaat aatgatttaa aggaaagaat
    10561 aagattaaaa tatattgaat ggagaactac tcttaaatct gaaattgttg aatcactaga
    10621 aaaatataat agtagcgaaa atgaacagga tgctgaatca ttttcttttt tactcatgtc
    10681 aatagttgat ggtttagttg tccaaagttt attaaaaaca gaaaaaatac cttatgaaaa
    10741 tatagcttct tttttagtta atcattggat ttaaacttaa tacttagata attaataaaa
    10801 gtgaactatt taagttatct actttaacag ttcactttct tatttattct caataatttt
    10861 tacttaaaac attcaatttt tatttaaacc ttcatggaat cacaaaataa aaatctctta
    10921 taaatttaaa atgtttttat ttatgttcat gtgtatgccc atctgaatgt tcatgaccat
    10981 gtgtatgtgt atgctcatgg ctatgctcat gagtacctga aaaaccatca tcatgattat
    11041 ggtcgtgacc tacaccattt acatgctcat gttcatgccc atgactgtga gaatgttgat
    11101 gtgaatgttc atggttatct cctccacagc atccttctcc tccagtccca caacacccac
    11161 ttgtatgtgg attatgatga tttcttacta caaatctctc tcttaacata attcttatac
    11221 ctcctagtat attattgagt acttcatgta ccccattaac tatggtatac atctaactag
    11281 gtataatctc aatacatatg tcatttttta acatatataa ttaacatata taatcttaaa
    11341 gaaatttatc cttaaaacct ccacctttta cttcttcaac gttattgaca gaaataaaag
    11401 cttcactatc catatcataa attaaatctt taaatttacc tatttcattt gcagatatta
    11461 tgcaataaat catctttttc ttattttgtg tatatgcacc ttctgcctcc aaaaaagtga
    11521 ctcctctacc cattttattc attatcactt tggatatttc atcatattta tttgatatta
    11581 aaagtataga tttttttcta tcaaagcaat cttttcctat atccatagta aaagaaatta
    11641 tatacattgt aattaaagtg tacatcacca atttagctcc aaataaaaaa gctcctgcac
    11701 atactacaaa aaaattaata aataaaaatg tatttttcat aggtatatca tactttcttt
    11761 tcattatggc tgctattata tcaagtcctc cagcagtagc tcttgcttta aaagttaacc
    11821 ccatacctat accagttaat gcaccaccat aaatacactg tagcatagta tcatctattg
    11881 ggaaatattt agcaatatct tgtgttagcc ccagtgctag agaaaatagt aacatattga
    11941 caaaacttat tagcaaaaat ttattatcaa aatactttct agctataata aatattggta
    12001 tgttcatcaa gaaacttgat attccctgat ttataccaaa taatttgtat aatataacac
    12061 aaattccagc tactcctcca cttaataact tggctggtgc tagatataaa tttattccta
    12121 aggttgatag aatcataccc aatataatca gacaatattg taaaaatata ttattatcaa
    12181 tacttagctt tttactttca ccatacatca aaacgcaccc ctttgcataa taaataaacc
    12241 accctgcata acacacgata aatttacaaa taaatttatc agaagtagtt tcctaaaaat
    12301 attattcatc ctcacttaaa cgtttattca ttaatattct atcacatgac ataaataatt
    12361 tatatgattt atacagattt atttattgta aattttggaa tattaaaaca ttttattgaa
    12421 tagataatta tattacataa aaaatcccta tagaaatcta taaactaatt tctataggga
    12481 ttttgattaa ctaactattt ttttataact tttatacctg tcatatggtc atttaagttt
    12541 tgttcctcta aagatttatc atctactctg tttatttcta aagctaaagt ttcagacttg
    12601 atatattcat taaaatggtc aacagcttta gcaatttcat catcaccaca gtattctatt
    12661 actatattat ctaatacttc aaagttatta gattttctta attgctgtac tttagatata
    12721 aattctctag cataaccttc attaatcaac tcttcagtta gcttagtatc tagtataaca
    12781 aaaagattgt tttcaacaga tacattaaat ccttccttag cagttatacc tattaatact
    12841 aaatccttat taaattcaaa agcttcacca tctaaatcaa ctgttaaagt ctcacctttt
    12901 tcaagtttat tagcagtttc atgagcattt aatttactta atgctccaac gaataaattc
    12961 atcttagaac ctaataatgg ccctgcttcc ttaaagtttg gttttaaact aaaattcata
    13021 tactcatcta aatctttagc aaatattacc tctttaacat taagctcttc ttttattaaa
    13081 tcaactacat cacttattgt atcttcaaac ttaccatcta ctaacacttt ttgtaatggt
    13141 tgacgaactt ttattctttc tacttctctt gaagctctac ctaaagtaac taagttttta
    13201 gctaaatcca ttttttcttc taatttagta tctactaact cttcattaca tttaggatat
    13261 tcagctaaat gaacagatac ttctcctgtt aagtttctat acatttcttc tgacatatat
    13321 ggtgcaaatg gagctatagc tctacaaaga ccatgtaaca attcataagt tgtattgtac
    13381 actgcttttt tatcttctgt taattcagtt gcccaaaatc ttcttcttga acgtcttata
    13441 taccagttag ataaatcatc atttataaaa tcttgtatca ttcttaaagt tttatttaac
    13501 tcaaatatag ctaaattttc ttctacatct ttcattaaat tattgaactt agataatatc
    13561 catctatcaa gttctggtct atctttatat tctacaaaaa attcagttgg atttatatca
    13621 tctgtgtttg catataaagt aaagaagtta tatacattct tcatagtacc tataaattta
    13681 ctttggattt cttttaatcc atccatatca aatttagttg gagtccatgg tggagaaaca
    13741 tatagtaaat accatcttaa tgcatctgct ccatattggt caaataattc cattggattt
    13801 actgtatttc ctcttgattt actcattttc ttaccatctt tatcaagtac aaggtctgga
    13861 actaaaacac tcttatatgg tgcttttcct aatacaaatg ttgatactgc aagtaatgag
    13921 tagaaccaac ctctagtctg gtctatacct tctgatatat agtcagctgg gaacaattgg
    13981 tcaaagtttt ccttattttc aaatggatag tggtgttgag caaatggcat agccccacta
    14041 tcaaaccaac agtctataac ctctgttact cttgtcattg gttttccaca tttttcacat
    14101 tttaagtgta tatcatctac atatggtcta tgaagttcaa ctgtttctgg atttacatct
    14161 tctatagctt tttcagctaa ttcagctctt gaaccaactg aatctgtatg accacattca
    14221 catctccata taggaagtgg agttccccaa tatctagttc ttgatattgc ccagtcattt
    14281 agattttcta accagtttcc aaatctcttc tctcctacaa aacttgggaa ccattttaca
    14341 ccattattat tttctattaa tttatcttta agtttagtca tctctatata ccagcttggt
    14401 tttgcatagt atactaatgg agtttgacat ctccagcagt gtggataatt atgaactact
    14461 ttttctttgc tatataattt attttcagaa gctagccatt ttattatttc aacatctagc
    14521 ccatcttcca ttacaaatct accttcccaa ggagtagatg taaatttacc agtttcatct
    14581 actggttgaa taactggtaa atcatatctt ttacctgtgt tgtagtcatc ttcaccaaat
    14641 gctggtgctg tatgaactat accagttcca tcttcagtag ttacataatc tcctactgta
    14701 ataaaaaatg cttttttgtc aacttctaca aaaggcatta attgttcata ttctaaacct
    14761 tctaggtctt tacctttcat ttcttctaaa acttcataat cttcacctag tactttatca
    14821 gctaaaggtt tagatacata atatacctca tcaccttttt taacttttaa ataatctaca
    14881 tcagcattta ctgttaatga aacatttgat ggtaaagtcc atggagttgt tgtccatgct
    14941 aagaagtatt catcagcatc ttttttctta aatttagcta taactgtatt agtttttact
    15001 tctttatatc cttgtgcaac ctcatgacta gcaagaccag ttccacatct tgggcaataa
    15061 ggaagtattt tatgcccttc atatatatat ccttctttgt tgaatttgtt tagtatccac
    15121 catacagact ctatatagtt attatctaaa gttatatatg gattatctaa atcaacttca
    15181 taagccattc tctcagtcat tattctccat tgtttttcaa atgagaaaac tgactctcta
    15241 catttttggt taaattcagc tattccatat tcttctattt gttgcttact agtaagtcct
    15301 aactctttct ctacttgtat ttcaactggt aatccatgtg tatcccaacc agcttttctc
    15361 tttacttgat aaccagacat tgttttatat ctacaaactg aatctttaag cgttctagat
    15421 aaaacatggt gtactccagg atttccatta gctgttggag gtccttcata gaatacgaaa
    15481 cttgggtcat ctttcccttt ttctaaagtt ttttcaagta tatttatgtc tttccaataa
    15541 tcaaaaactt gtgcttctgc ttgttttaca gaactgtcta ccaatggctt aaatttcgcc
    15601 atgtaaatca ccctttccta ctaaatatta taattccaaa attttttatt ctttcacata
    15661 aatttaaata ctaaaaaact cgcccccttt aaaccaaagg gacgagttat aaatcgcgtt
    15721 accaccctaa ttctatatgt aaactaaata ctagctacat ataacactct aatagtataa
    15781 cggtactaac cggcacagct tagtagaatt taatcgttca gcctgcagct caagagtgat
    15841 ttttatcttt ataaattcat tggttctcag catacccaat tctctgtaaa attatctaaa
    15901 gataaatgtc tctatcaacg cttttaaaaa tttatctgtg tttatatgaa attctataac
    15961 aaataatttg aatagtcaat atatttttga aaaatataat aatttctatt tttcttacat
    16021 ttttatccta tttttaatct ttgttataga tttctcaaac tcacacaatt attctacata
    16081 aaaaataaac aaattacaag cttattctaa agttgtagca gcttcatcat tactataatt
    16141 atacactgtt gttccttcaa atgcgtttac acatttttca tctacatcat aaaaaatctc
    16201 atcaacactt cttatttcat cttctaacag tgatttaaat ttatttctaa atatcttaaa
    16261 ttctttgact aaagcatcat actcttttct tatctctata acacggttat tagcttgttc
    16321 tataatttgt ctagctttta aatcagcttc ttcaacaatt atcttagcct ttttattagc
    16381 cgcgctacaa gtgtcttctg ctgcactttg agcagttatt aaagtagctt ttagtgtttc
    16441 ttcaatattt tcatacttgt ttacttggtc ttgatataac cctaattttt ctttaagagc
    16501 tgtattttcc ctacatagag attcataatc ttccttgatg atatctaaaa attcatcaac
    16561 ctcttcatct ctataccctc ttaaaccttt tttaaactct ttattttcta tctcaattgg
    16621 agttagcatt acatttcctc ccagctataa tttaaattag tccttataca attaatcttg
    16681 cttgaacttt tatttttcct tttttagtaa tatctcctat ttgtgttacc ttagctcttc
    16741 ctttgcctct aatagaaatc aaatcatcat tttttactat tttagaagtt gaagttatct
    16801 tttcataatt gacatggact ttttctccat ttatgtattt tgcactatct tgtctagata
    16861 tattgtaaat accacttatc acacaatcta acctatctga agatactgta aatgatactt
    16921 ctttatattt tgaagaacta ttaacaatat tttctctgga aatttccttt acaattacat
    16981 tatttcttga aaccttttct aagtttacaa ttataaaatc gcaaatatca ctacttacaa
    17041 ctacttgaca aaagctatca tgtataatta tatctccaat tttttctctt tttataccta
    17101 gacccagtat tgaccctaag taatctttat gagatatatt tttaaatttg aaattccctt
    17161 ctatttgtaa aaatctaaga gtatcttcta tatcttcata ttccatgtaa aatggataaa
    17221 taaatacagt gcttctttca gcttgttcat aacctccatc cacactgtat tttatttcat
    17281 ttgtagaatt taatattgct acagcatttt tcacttcata tggattaaga aactccgtag
    17341 acttaacatc atagtttttt atacaactat tagccttgtc tatcacttta aacattttat
    17401 ttttcaagtc tatatccttt atgtgatttg ttagttttaa tttatccatc ctatcacctt
    17461 agaatataac caatactaat tgtcttagga acatcaataa tactattgca attaaaggag
    17521 aaaaatctat aggtccattt gtatatttat acattataga ccttattggc ccttctattg
    17581 gctctgtaag attttccaaa atatcaaaaa ttttactttg tcttccattt ggaaaccaag
    17641 tcatcaagct ttttataact atcatccatg ctattatatc taaaagataa taaagtgcaa
    17701 ttcttattgt tcccatatat taaccgcctt tttactattt attttgccaa gggaagaatg
    17761 ctttactttc taattctttt ttcatatttg catctatatc cacattatta ggagctagta
    17821 taaatattga tttagaaacc ttttgtatac ttccatctaa gacataaact gccccattca
    17881 taaagttaaa tatagattta cgaacttcag aattagtcaa tccttccaaa ttcactataa
    17941 ctgcccttct ttgttttaga tggtctgcta tagttgcagc ttcatcataa accttaggtt
    18001 caactattac aactttcatt tggctagttg tatgtaaatt tacaatttta tttgcttttg
    18061 cagtactaaa gccactgttc atttcttctt cttgaactat atcgtccatg ccactttcat
    18121 attcatcttc aatgtaatct tcttcttcat caactatcca attcttaaat ttagatatta
    18181 ttccatttga cattattaac ttcctcctta aaatttattc aaatttgagt aattattttt
    18241 tattgtagtt tctttctcca aagattgatg ttccaactct aacaatggta gccccttcct
    18301 ctatagcaat ttcataatcg tgactcattc ccattgacaa aacatccatc cctacattag
    18361 ggatgtttag ttcttttatt tgttttgata aatctttaag acctttaaat acacctctta
    18421 tctcatcttc atcttctata aaaggtgcca ttgtcattag accctttatt tttatatttt
    18481 tatatttttc tgacacttct ttgacaaagt ctacaacttc ttctctatca agtccatgct
    18541 tagactcttc tttagatata ttcacttgta ctaagcaatc tatttctctg tttatttgtt
    18601 ctgcacgttt ttgaatttct tcgcataatg caattctatc taaagagtgt atcatacaaa
    18661 ctttatcgat tatgtactta actttattgg tttgcaaagt tcctatcagg tgccagttta
    18721 atttatcacc tataatatca tactttctag ctaattcttg gggtttattt tcaccaacag
    18781 aagtgattcc ttccctcatt gcctcattaa ctaagtctac atcaacagtc tttgtgactg
    18841 ccaaaagggt aatctctttg ctgtctctat ctactttttt tgcagcttta tcaattttgt
    18901 ttcttatctc agacaaattg tctttaatag aacccattat tatcacctac tttatcctta
    18961 tatttgtgtt tatactgtta ggtcttaaaa ttattttgtc atatagatta acacttgtaa
    19021 ctccatttat gtcattttta taataatcca caaatacaga agattcattc tcataagtta
    19081 ttccttctaa tatgacaaat tttacacttt gtgattgttc atcaattaca tatacaccac
    19141 gtttattgtc ttttgttttt atagaagttt taggtatttt taaacattcc atctgattat
    19201 atattatatc aaattcttcg acacttgtat cctgatttgc aacaatttgg ttacttattt
    19261 ttaattttac cattatttta ttattatttt catatatttt gtaaactttt gcatctaatt
    19321 tttgctcatg atattcaatt attacatttt gatttttttc aaagttatta gaatcttctt
    19381 tactgatgta tgtagataga taattactct ggtcattggc atctttttct atagttcctt
    19441 ttacatgaat ctttgcatca actttttcat tttttaacac caacgtatct acatttttgc
    19501 taattatcat tactaatata ttaaatacta aatatataag aataccaagt atcactaatc
    19561 tggtatattt tacctttttc aaagactctc cccctataaa attactttca ttataagtac
    19621 ttcttctaaa aaatgtttat tcctttttta taagctaata ttttacgttc taataattat
    19681 tttttccata ttaaatttat tttttatcaa tcttcctata caagactgca ttatttatat
    19741 ataattgtat tataaagtat aagtttaatt tacattttat acgttaagct tactttatat
    19801 gtttttatag ttatttttat ttttagatgc aatataaaac caattaagat ttaaaataac
    19861 ttttgttatg ttgacattta tttaggtaat catttatgaa ttaggataac gttatcataa
    19921 caaaagttta tgtcctaaaa aaaatacaag gaggattttc ttatgtcaga aattttatta
    19981 ggaacaggtt tacttttatt ggttctatgt tgtttcacaa tttttagtta caaggcccca
    20041 tatggtatga aggctatggg agctctagca aacgctgcat gtgctacttt cttagtagag
    20101 gcattcaacc tttctttact tggtgatgtt ttaggtatgg aattttttag aagtgttgga
    20161 gctgctaatg gtagtcttgg tggagttgct gctgctatac ttgtgccttt agccttaggt
    20221 gtatctccag tttatgcagt tttaatagga ttatcttgtt tagatttttc tatattatct
    20281 ggattcgttg ctggatactt tgtttctttc ttaattaagt ttatagagaa aaaagtgcca
    20341 cctggagtgg atttagtggt tgtaattctt ctatgtgcac cgctatctcg tcttatagca
    20401 tcaaatgtag acccattagt taatagtaca ctactacaaa ttggacaagt tttgatagaa
    20461 gctaccaaca ttagccctat aataatggga attatactag gaggtctaat aacagtagtt
    20521 ggaacgtctc cacttagttc aatggctctt acatctataa ttggtcttac tggtcttcct
    20581 atggcaatag gagcattagg tgcttttggt tcagctttta tgaactcaac actatttgca
    20641 aaattgaaat taggttctaa aaaagatatt atatctgttg ctattgaacc attaacccaa
    20701 tcagacataa tttcagctaa tccaatacct atatattcta ctaatttctt tggaggagcc
    20761 ttttctggta tcattgtagc cttgatgggt cttgtaaaca tgacaccagg tacagctaca
    20821 cctgtggctg gttttgctat aatgtttgct tataatccag ttcaacaagt tcttataaca
    20881 gctggtttat gtgctttatt caatgtaatt gcaggatttt taggttcaaa aatattcagt
    20941 acctttaaag ttcttactgc tggtgaaata cgtggtactg atgtagaaga agaaattgct
    21001 taaaaaacaa taagatttat aaatttatat ctcaagtagt agagttttat attgtaggca
    21061 attttattaa ttgcaaacgt tttatttttt atttatgttt atgattatta tgtgtgttga
    21121 atatttagat aaatttttat ttattatttt tatttagatt tttgtttagt tttttatttg
    21181 gttgatatat taggaataaa aattagtata gtttattact agttagatag cataactttt
    21241 tagatacata aaaaatttta tattaattag atattattaa aataaaagcg atacatgaat
    21301 ttttaaatgt ccatgtatcg ctttattttt gccataatct taacaactga tttttaaagt
    21361 ttattatctt aacaaagttc attatcttat ataatattta aatgcataga cttctttaat
    21421 ttaaccatct aaatatttaa ttaaatatta ttatatgtaa tataactaat ttttaaatga
    21481 atgtatagga gctggaatcc ttcctcctct ttgagtaaat aattcagatg aatttgtatt
    21541 tataggcatt actggtgctc gtcctaaaag tcctccaaat tctaccatat cacctacatc
    21601 acatcctggg gctggtataa ttctaacggc tgtagtctta ttattaatca tacctattgc
    21661 tgcctcatca gctatcatgg ctccaagcgt acctgctgta gtatttcctg gcacagctat
    21721 catatcaaga cctacagaac aaatagcagt cattgcttca agcttatcta tacttaaagc
    21781 acctttaata acagcatcaa tcatacctgc atcttcagat actggtataa acgctccact
    21841 aagtcctcca acatgtgaac atgccattac tccacctttt ttaacagcat catttaaaag
    21901 tgctaatgct gctgtagtcc catgagtacc aacaacttca agacccattt cctctaatat
    21961 atttgctacc gaatcaccaa tagcaggtgt aggagctagt gataagtcta ttatcccaaa
    22021 tggaacatcc aatctactag aagcttcctt tgccacaagt tgtccaactc ttgtaatttt
    22081 aaatgcagtc tttttaactg tttctgaaac aacatcaaaa ggctctccct ttactttctc
    22141 taaagctctc ttaacaacac cagggccact tacaccaaca tttataattc tatcagcctc
    22201 accaacacca tggaaagctc ctgccataaa tggattatct tctactgcat tacaaaatac
    22261 tactaatttt gcacaaccaa aaccttttgc atcttttgtt aattctgcag tttcttttat
    22321 gatttctccc atttctttca ctgcatccat atttatacca catcttgtag aacctacatt
    22381 tactgaagca catactttat tagtacttgc tagagctttt ggaattgact taattagtat
    22441 cttatcacct tttgtatatc ccttttgaac taatgctgag aatccaccaa taaaatctat
    22501 acctaaatct tctgcagcct tatccaatgt ctgtgcaaac tttacatagt cattttcatc
    22561 tgttgcacct gcaataatgg aaattggagt tactgatacc cttttattta caattgggat
    22621 accaaattca cgctctatat cttttccaac cttcaccaaa tctttagcag aactcataat
    22681 cttattgtat attttttctc tagctttatc tccatcaggg tctatacaat ctaataaaga
    22741 aatccccata gttatagttc ttatatccaa ctgttcttca tctatcatct ttattgtttc
    22801 aagtatattt cctacattca ctattatcac ctccccttac tgtctactac agattatgca
    22861 ttgaattaaa tatttcttct cgctgaattt ttacatccac tgataatttc ttacctcttt
    22921 caaccaagtc ctcaaccgtt ttctcaaaag aatttaatga tttctctaaa tcaactatca
    22981 taatcatagt aaaataatcc tgtaatattt tttgtgatat atctactatg ttgatatttt
    23041 gcttgtataa ttcatcacta attcctgcca ctatacctgg tttatccttt ccaattactg
    23101 ttaaaattgc tttcataata atatcctccc ttattttttt ataaatctta tatttttaca
    23161 aattgaacta tgtgttaaca tatatttcat ttatttgtta gtaaaccact ttttatgtat
    23221 atatttaata tattttaata cctatacatt catttgtcaa ttttttttca atattct
//
LOCUS       DAEPKC010000060        23124 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.060, whole genome shotgun sequence.
ACCESSION   DAEPKC010000060 DAEPKC010000000
VERSION     DAEPKC010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 23124)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23124)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23124
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.060"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            94..1326
                     /locus_tag="KR294_002372"
     CDS             94..1326
                     /locus_tag="KR294_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosine permease"
                     /protein_id="HBH0240443.1"
                     /translation="MQEREELVLNPVPKEERVGWLAPLFNMLGSNIAISELMVGGTLI
                     LGMTLSNMIITSIIGNLILVAIIMIQGYIGYKEGLNTYVLAKGAFGEIGGKYLISLLL
                     GITSFGWFGVQAGVAGLSVQKIFPSVNLTLVTVILGLFMVVFALYGFKAMAKFNYLVI
                     PPLMILMVWGVFKAFSTYGVEAIYNYTPQTTMSMVEGLNIVVGLVIVGAIISPDQLRY
                     TRRVKDIWIISFLGLGIISLFQQVAAGVMSMGAPTWDITEVLANLGFGWVAFVILILA
                     SWSTNVSNAYSGGLALKTIFPNVKRNVLTLVAGLIGTIIAATGIIFKFQSFLSFLGIA
                     VPAIAGIMWCEYYFIQGRTYKHREGINWIAVISWLIGFAASYYSSKINFLIPPINGIV
                     VSMVIYYILMKCFGIKDK"
     gene            1340..2146
                     /locus_tag="KR294_002373"
     CDS             1340..2146
                     /locus_tag="KR294_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase"
                     /protein_id="HBH0240444.1"
                     /translation="MGRKVKIGIIQQHSVLGDVKKNIEKAVEMIDDLGKQGADIICLP
                     ELFATGYNLESLGGVKTLELIREHNKYIEESMSEAAKRNNVYLISPYGTLEKGSTHVY
                     NSAVIFDRKGKIMGEYCKNHLWSLEAVYFKGGEKVEVYDADFGRFGVMICYDAGFPEV
                     SRELTLKGSEIIFIPSAWRIQDEDMWDLNVSQRALENTVYTVGVNLVSNDSNLILFGK
                     SKICNPRGTVITQLDTYREKYVLSEIDLDEIKKYREDIPYLKDRKSSYNI"
     gene            complement(2258..3127)
                     /locus_tag="KR294_002374"
     CDS             complement(2258..3127)
                     /locus_tag="KR294_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBH0240445.1"
                     /translation="MDLLHLKYFQTVARMEHITKASHKLNIAQPALSKTISSLEKELG
                     VQLFDRKGRYIVLNEYGRLFLKRVDSILDLVESSKKELQDTSLENSGEVKILSPAAAN
                     VLPSLLSNFRKLYPNITFNVSHTLPSSYKKSDFDLYISSSFTKLNSENSITLTCEEIL
                     LGVSINHPLSLKDEVYLSEVSDENFIVITKGENYREVIDILCESANFKPKIAFESDSP
                     YTIYALIKSLQGVGFICGKSWGLSQDPEIKLLHIKDIEFKRYLNLSWFSENYESKAVL
                     LFKNFLINYFKNI"
     gene            3499..4926
                     /locus_tag="KR294_002375"
     CDS             3499..4926
                     /locus_tag="KR294_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp14"
                     /protein_id="HBH0240446.1"
                     /translation="MKLTKSISSMLCLSLVLSLSPVAYANEISRTTVENTLVGQDRYQ
                     TAVEVSKKGWSSANEAVVVNSESIVDALAVTPFAKLKNAPILLTEKNNLNSQTEKELK
                     RLGVKKVYIIGLSSSVSNDVQKQLESNNLTTDRVGGSDRYQTALSIAKKIEGLKDISE
                     IAVVNGYTGLADAVSIGSVAATNGMVILPVSDASGISSFKDFIESKNINKSYIIGSTN
                     AVSDKIKQSLPNSERIGGADRNETNGKVIEKFYTSNKLNNVFVAKDGMKNQNQLIDAL
                     AVGVLASKENSPVLIVGEQLSATQKSVFSNKNATSITQVGSGGNENAFKELKDLQANS
                     NNKRVMYVTNTDKVNIRNDATIEASVIGYLNNGDEVEVLDVLKTGWVKIKYNEGIGYV
                     SGSYLTNNKPDNSNENIKIKYVKEKDGLNVRKGPSTEDEKIGHLSYGSKVETIEMFAT
                     GWVKIKYNGGYGYVSNDYLSDTPVI"
     gene            complement(5003..5272)
                     /locus_tag="KR294_002376"
     CDS             complement(5003..5272)
                     /locus_tag="KR294_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240447.1"
                     /translation="MKFEYYYLIQDIAGILLAFIGLRMSIIGFRILSMRGLSINTLLI
                     VIKYCLFTIAGLNLLISKFGIRHWIWSVCMLIISIIINPRIKVSK"
     gene            complement(5275..6717)
                     /gene="nhaC"
                     /locus_tag="KR294_002377"
     CDS             complement(5275..6717)
                     /gene="nhaC"
                     /locus_tag="KR294_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HBH0240448.1"
                     /translation="MKMNTERKIPSFRYSLLVMLAIIALTSVGIVVFNASITTMFLLS
                     WLIVVPAAMKLGYTNDEIEAFGFEVGKDAFQSNLIILSVGVLIAAWIAAGTIPTVVYS
                     GLTIITPKYFLLTTLIVCSLTSVATGTSWGTLGTSGIAMMSIGTSMGIPLGLTAGAVI
                     SGAFFGDKMSPLSDSTNLAAAVCKTDVITHMKHMFYTTGPAYVICIVLYTVIGFKYSN
                     NTIDYVQINQIKDVLNSNFHIGLVAMIPIIFLLLLLLLQKPPIISILSSAIMGLIIAV
                     FQEGEKIGDVLNYMLSGFTIDTGFVYADKLLNRGGIMSMAETVLLVFVVFVIAGILQK
                     TGFLEVLLQPLITKIGKSRTKLVGSTFIVSYFANAFSSSMMFTSVFVGTLMSPIYKEF
                     KLKPQNLSRIIEDTATLGGPLIPWNSNAVFCAQTLGVSPLEFIPYCFLSWITPIISFI
                     YGVTGFTMLTYTDDEIEELEIFDTAQRRVD"
     gene            complement(6742..7908)
                     /locus_tag="KR294_002378"
     CDS             complement(6742..7908)
                     /locus_tag="KR294_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBH0240449.1"
                     /translation="MNYNFNEIVDRSNNFSSKWSEMEKKYGTNDLLPMWVADMDFKAA
                     PCIIDSLKNRLEQEIYGYTTRPDSYNESIVNWLDRRHNWKIKSEWLIYSPGVIPAISL
                     LINELTKANDKIMIQEPVYSPFNSVVKNNNRELIISPLQKLENGNYIMDYEDIENKIK
                     DVKLFILCNPHNPVGRVWTKDELKKLGDICLKHNVKIISDEIHSDIILKKHKHIPMAS
                     ISKEFEKNTITCMAPTKTFNIAGLQSSYVILPDEKYYKLLDDAFTRIDIKRNNCFSLV
                     ATEASYNNGESWLESFLEYLESNIDFAIKYINENMPKLKVRKPEGTYLLWVDFSALGL
                     SDEELESILVQKGKVALNQGNSFGIGGSGYQRINLACPRSMLEEALIRIKNAIN"
     gene            complement(8133..10253)
                     /locus_tag="KR294_002379"
     CDS             complement(8133..10253)
                     /locus_tag="KR294_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH0240450.1"
                     /translation="MKQMELAIVSLKKDAGEIYENQIRQFLGDNLKINLYSFEEGNLK
                     FFKEKLILLSAYLKYDEIVKLSHYDAQIIVPKLTFEKNSIDMISKLEKDKIIYVYNLS
                     KDMAIETISLIHRLGIDNINILPCYPEIEFTPTDAVILTPGEKILPKFKNCEVIDLKY
                     RIIDLSCIVEIATKTKLKHLIKDDLIKKYVEKIIPTSYSTGELLLDANKFERQFDLLL
                     SIIDDGIICTNNDGIIQFYNHMARKILSINANEMIDSFVGDCIKDINFQSILTNKTPF
                     FEKLIKINHIDINLEIKHIQLNVFDGFILKMTKFSQLEKKQAKLRAQLVNSGNISKYT
                     FDDILGSSIQTINTKKIANKMAQSNSSILIIGESGTGKELFAQSIHSASRRKDGPFVA
                     VNCSTFQENLLQSELFGYDEGAFTGAKKGGKIGLFELANNGTIFLDEIGEMDLNSQSK
                     LLRVIQEKQVRRIGSNNVIDIDVRIIAATNRNLKELVSKNMFRRDLYFRLNVLPLKIH
                     PLRERPADIFEIFGSLKYDIPCNFILSEEVKEIFKMYRWEGNVRELRNLGEYFCYLEK
                     DIIEICDLPEYILDTIDSNYSRTVCNKVSNNIKKYQFNIGKDKNIMKYDYNFKRSLDE
                     YIFILDNLKKAYDLKERIGRKSLCKIALEENRFLTEQQIRNMLLELQDFGLVDILVGR
                     GGSIITSKGVEFLKNINRSNKLNS"
     gene            10486..10887
                     /locus_tag="KR294_002380"
     CDS             10486..10887
                     /locus_tag="KR294_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240451.1"
                     /translation="MKKCLYCNRDIKSPNNKLAIKYDDNMNIYPCRAECKEKIEEYIA
                     KKPTYKFINILEVLLGVGGIFCFLSKWTIAAQVVLGIDALVIFLFPLAGFKMNGKLSM
                     EQTKNQSRSIAISILAFIVIITVLYFKQIGK"
     gene            10930..11223
                     /locus_tag="KR294_002381"
     CDS             10930..11223
                     /locus_tag="KR294_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HBH0240452.1"
                     /translation="MEERKLAPNNEREALIKRLKRIEGQVKGIQKMVEQERYCVDILV
                     QISAIRSAINRVGTIILENHIKGCVAESIKHDDADKTEEMIKELMDTINKFTK"
     gene            11238..11678
                     /locus_tag="KR294_002382"
     CDS             11238..11678
                     /locus_tag="KR294_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SoxR reducing system RseC family protein"
                     /protein_id="HBH0240453.1"
                     /translation="MNQQGFIMEIVDDRTAKLKMQRHSACAACGKCATTNSAESKEIL
                     VEVDNTIGAKVGDHVEVSMDNMNVLKAAVMAYIIPLIALLVGTIGTYYILGAIGMTTG
                     VEAISGLVGICLTIICYLYLKKNDKKFRDSREFIPVITRILIDL"
     gene            complement(11770..12243)
                     /locus_tag="KR294_002383"
     CDS             complement(11770..12243)
                     /locus_tag="KR294_002383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBH0240454.1"
                     /translation="MTDMSMILHFLFSGVATAGFAVFFNAPLYLLLPAGVTGGIGWIV
                     YVYLFNFTTNAVFAGFIAAALVSACSETLARKLKQPAIVFVIPGILPLIPGIGLYNTM
                     LSLIQKNYSLAMSKGTDALFLSAAIALGVLVVTSFVRTLNLLKIRKNFIPYRKSK"
     gene            complement(12243..13031)
                     /locus_tag="KR294_002384"
     CDS             complement(12243..13031)
                     /locus_tag="KR294_002384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBH0240455.1"
                     /translation="MNQNEELEYKKNILKLALFVGELMIKNGAETSRVEDSVLRICRS
                     RGFYHVNIFTTPTVIIISDEKFDGFSFMKTIQSRGINLNKISLLNSFSREFVSDKEYD
                     IDNAIARLYEIQDVKPYPLWLFYSCTGIASACFACLLGGNYVLNFILTFIIAIFAAIT
                     YDKTMKISAISAFSCLVSSFLIALSGVLLVEIGILDDPKMLIVGAIMPLLPGVAFIKA
                     IRDLISGNLISGISRAFDAAMIIIAIASGVGFVLDTWYRIGGPF"
     gene            13359..14603
                     /locus_tag="KR294_002385"
     CDS             13359..14603
                     /locus_tag="KR294_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HBH0240456.1"
                     /translation="MFENLKKADPEIYESMKRELKRQQRNIELIASENIVSVPVMETM
                     GSHLTNKYAEGYSGKRYYGGCEYIDEVETLAIDRIKKIFGAEHANVQPHSGANANIGV
                     YFAMLKPGDVVMGMNLSQGGHLTHGAPVNISGQYYKFYEYGIDKDSGLIDFDEVRKIA
                     HEVKPKMIVAGASAYPREIDFKKFREIADEVGALLMVDMAHIAGLVAAGLHQNPCEVA
                     DFVTTTTHKTLRGPRGGVILCKEKYAKDIDKAIFPGIQGGPLEHIIASKAVCFKEALS
                     DEFKEYQVQVAKNAKALAEELIKRDFKLISGGTDNHLILLDLTNKNITGKAAEKRLDD
                     AYITANKNTIPFDPNGALVTSGIRLGTPAVTTRGMKEEDMAIIAEAIDLCLTYDEESK
                     ARTLVVGLTEKYPLYEEYNIMD"
     gene            14926..16023
                     /locus_tag="KR294_002386"
     CDS             14926..16023
                     /locus_tag="KR294_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-diphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HBH0240457.1"
                     /translation="MKVLILTGKFGMGHYSASNSLSEDIKAKFDNSEIIIKDIFEYIM
                     PNYSDKMYKTFSILVNRGSSLYNLFYKCAENGKKDIKFTFSDYFLNKLDTLLHEVQPT
                     VVISTFPFCSQLVSRYKEKYNSNLPLITCITDISSHSEWISKNTDCYLVASKSTKEEL
                     VFKGIDESKIKVNGIPVKKEFKRIEHVNHSTKKNILIMGGGLGLLPKSEQFYKELNSL
                     EGVKTTVITGNNKKMYYKLYGRYENIEVVGYTNEVYKYMKDSDLIISKPGGITLFETI
                     YSELPILAFNPFLQQEIDNASFILNNEIGRILGKNKKYYVDEIKDLIYDDATLKEMSS
                     NMKELKKQFDNNTLENILFSLDEQGACRECM"
     gene            16014..16712
                     /locus_tag="KR294_002387"
     CDS             16014..16712
                     /locus_tag="KR294_002387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBH0240458.1"
                     /translation="MYVVGLIIVVALIFLVHSIIPTYYNKLLNKEVLKNMAGENEIAL
                     TFDDGPDKRYTEKLLDVLKENDIQAMFFVVAKNAEKEPEIIKRMLRENHIVGLHSLEH
                     RNAWLYSYSYVKKDFIESTNIMKNLGVDVNYYRPPWGHTNIFSNSFVKKYNLKMTLWD
                     VMAEDWEKDSTVDIIINKLMSRTKENSIICLHDAGENSGGAVGAPERTIEALKIAIPK
                     LKASGLKFVTPERM"
     gene            16715..17779
                     /locus_tag="KR294_002388"
     CDS             16715..17779
                     /locus_tag="KR294_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HBH0240459.1"
                     /translation="MISKTEKKNKCLGSVAFLVLLMGITGYFVFRGQSVESLIKSLKG
                     ASPMFILIGFAMMFIYVACEGINIYLGMKALNQKTTLLKCMGYAFIGFYFSSITPSAS
                     GGQPAQVYYMKKDDINISYSSLILLVIVVIHQVVILAYSGIMFIMEREFILNNVSGMN
                     ILLIYGVITNVALVIGVIAIIFSKKLVNNFIISITNLLGKLRIIKDVESSRKVIISQI
                     EEYVKGAQYIKQNPKLVVQILVITIVQITSMFLVPFFVYKAFHLSTYTVFEILAIQSL
                     LNIAVSSLPLPGAVGASENSFMTLFKIFFPGHLLVPAMLLSRGISFYAFVAISGLICI
                     VVHVKSSEKVKAVKKVAYVR"
     gene            17962..18666
                     /locus_tag="KR294_002389"
     CDS             17962..18666
                     /locus_tag="KR294_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0240460.1"
                     /translation="MNKEIPKKILVADDNPEIREIVEILLTGEGYEVIMATNGEEAVN
                     LVDSTIDLIILDVVMPVKTGFVACNEIREKTTAPILFLTAKTQDSDKVIGFSAGGDDY
                     LSKPFSYSELISRVKSLLRRYYIYQGKEKEREPNILKTKELCVNLDTQDVTLNGEPVF
                     LTTIEYSILILMLKNRKKVFSSENLYETIWDEQYFYTANNTIMVHIRNLRKKLEKDQK
                     NPQYIKTAWGKGYYID"
     gene            18659..19981
                     /locus_tag="KR294_002390"
     CDS             18659..19981
                     /locus_tag="KR294_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH0240461.1"
                     /translation="MINKIKPSKLGVILLIYVVISAAVAFILNIPFYSAVESIVKDVS
                     EGKVYFKREVNQLMDNFQTYVNNNGIRADDGDDIAKWNSDNWFVSMKIYKGNKVFYDT
                     LYYPNEVPDKSEENEFYSSPMARNYEIQFSDIKANIVVVALFRFRFQNFIEAISITFM
                     ALTFIITFLLLFSRKIKYLRKIEMGIKIVESGSLKYRIPVKGNDELSSLASSINEMSH
                     TLENQLIKEREMKNKNKDIVTSISHDVRTPLTSVICYLDLIKDHKYNSPEQLEQYIKN
                     VRSKAYQIKDLTDDLFTHFVNSGEEVSKGYEKINANEFIFQLLLDSSYTLEEKGFHIT
                     IENELYNQYHIYVDVTQFRRIFDNLCSNIIKYARKDKPIVFLIKVEDSKLLIIQKNRV
                     SNFSKNVESFGIGIKNCEKIVAYHNGSINVNSDDKEFAIEISIPAKES"
     gene            20168..21541
                     /locus_tag="KR294_002391"
     CDS             20168..21541
                     /locus_tag="KR294_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240462.1"
                     /translation="MVLTGAHYIYILFMVIILITMIMKKDTIVPCILGVFFMGLFFEK
                     NIFGAITAVFNSFIISLNELGPIILIIAIMVALSKALEANNAIQYMVRPFSRVIKNSN
                     TAFFVTGFVMLVLSWFFWPTPAVALVGAVFLPVAMRAGLPAIGVAVALNLFGHGLALS
                     TDFVIQGAPSITAGAAGVAVSYVINDGMILFWVMGIVTISMAFYTLKRDINKGMFREE
                     LKGFESEEVEAFNGKSKIATILVALGFLADIIAMYVFDLKGGDASALLGGTAVFLIII
                     INVINFGKDSLENVCENIIDGFVFGIKIFGAIIPIAAFFYMGEVAPLTGVFGKVLAPG
                     SQGLLSDIGIALSQTIPLNKFAVSGIETVVGAITGLDGSGFSGISLVGSLASVFGTAI
                     NASVGALAALGQISGIWVGGGCLVPWGLISAAAICGVSPIELAKRNFVPVITGLVVTT
                     IVAMFII"
     gene            complement(21913..22851)
                     /gene="pdaA"
                     /locus_tag="KR294_002392"
     CDS             complement(21913..22851)
                     /gene="pdaA"
                     /locus_tag="KR294_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="delta-lactam-biosynthetic de-N-acetylase"
                     /protein_id="HBH0240463.1"
                     /translation="MFRKVLHYLTLLSISIFFIVGCSNSQNNQNENQNKETQLQEDKE
                     KIDSGKDTSNVIVSDGTDKPSKATTNNDNNKLDVSSLDNTTLDWFYIPNNKHKTPEVN
                     TDIEFKFSDYDALYNGPTKDGQKTLYLTFDEGYENGYTTKILDTLKQNQVKAVFFVTA
                     PYIKENKDLVKRMVSEGHIVGNHSKTHPSMPTKTSNLKNFNDELYDVEKLYKDVTGKD
                     MVKFFRPPMGKYSEKSLAMTKNLGYKTVFWSFAYRDWDTDKQPSHEEATQKIMDNLHD
                     GSILLLHAVSKTSTEILNDFISNARKLGYEFELLEY"
BASE COUNT         8506 a         2883 c         3669 g         8066 t
ORIGIN      
        1 attacaatta tataaagaaa aattctatta atagtgaaaa aaaagtagaa aaaagtagaa
       61 attattcttt tataaagaaa gggagggata atattgcaag agagagaaga attagtttta
      121 aatccagttc caaaagagga aagagttgga tggttagctc cattgtttaa tatgcttggt
      181 tctaacatag ctatatctga actaatggtt ggaggaactt taattttagg aatgactctt
      241 tctaatatga ttattacatc aattataggg aacttaatat tagttgcaat tattatgata
      301 caaggttata taggttacaa agaagggtta aatacgtatg tattagctaa gggggcattt
      361 ggagagatag gaggaaagta tcttatatct ctattacttg gtataactag ttttggatgg
      421 tttggtgtac aagcaggggt tgcaggacta tcagtacaaa agatatttcc aagtgtaaat
      481 ctaacattag ttacagttat acttggatta tttatggttg tttttgcact gtatggcttt
      541 aaagctatgg ctaaatttaa ttacttagtt ataccaccac ttatgatatt aatggtgtgg
      601 ggagttttta aagctttttc tacttatgga gttgaagcta tttataatta tactcctcaa
      661 acaactatga gtatggttga aggtcttaat attgtagtag gtcttgttat agttggtgca
      721 attatatcac ctgaccagtt aagatatacg agacgagtaa aagatatttg gattatcagt
      781 tttttaggtc tagggattat ttcattattc caacaagttg cagctggtgt aatgtctatg
      841 ggagcaccta cttgggatat aacagaagta ttggctaatt taggttttgg atgggtagcg
      901 tttgttattt taatacttgc atcttggtct acaaacgtat caaatgctta ttctggtgga
      961 ttagcattaa aaactatttt tccaaatgta aaaagaaatg ttttgacttt agttgcaggt
     1021 ctaataggta caataatagc agctactggt ataatattta aatttcagtc atttttatct
     1081 ttcttgggaa tcgcagttcc tgcaatagct ggaattatgt ggtgtgagta ttattttata
     1141 caaggaagaa cttataagca tagagaagga ataaattgga ttgcagtaat aagctggtta
     1201 ataggttttg cagcgtcgta ttatagttca aaaataaatt tcttaatacc tccgataaat
     1261 ggaattgtag tgagtatggt tatttattat atattaatga aatgttttgg aatcaaagat
     1321 aaataaaggg ggcaattaca tgggtcgtaa ggtgaaaata ggtataattc aacaacacag
     1381 tgtacttgga gatgttaaaa aaaatataga aaaggcagta gagatgatag atgacttagg
     1441 aaaacaaggg gcagatataa tttgtttacc agaactattt gctacaggat ataatttaga
     1501 gtctttaggt ggagttaaaa cattagaatt aataagagaa cataataagt acatagagga
     1561 atcaatgtca gaagctgcta aaagaaataa tgtatacctg atatctccat atggaacctt
     1621 agaaaaaggg tctacacatg tttataattc agcagttata tttgatagaa aaggtaagat
     1681 tatgggagaa tactgtaaaa atcatctgtg gtcattagaa gcagtatact ttaaaggagg
     1741 ggaaaaagta gaggtatatg atgctgattt tggtagattt ggtgtaatga tatgttatga
     1801 tgcaggtttt ccagaagtat ccagagaatt gacattaaaa ggttctgaaa taatatttat
     1861 accatctgca tggagaatac aagatgaaga tatgtgggat ttaaatgtat ctcaaagagc
     1921 tttagagaac actgtatata cagtaggtgt aaatttagta agtaatgact ctaatttaat
     1981 actatttgga aagagtaaaa tatgcaatcc tagaggtact gtaataactc aattagatac
     2041 atacagggaa aaatatgtat tatcagagat tgatttagat gaaataaaaa agtataggga
     2101 agatatcccc tatttgaaag acagaaaaag tagctataac atataattct atactataat
     2161 acaagttcaa tataaaatga taaaaagagg atgtatcaat attaagatta aatttattat
     2221 actttgatat atcctcttta atattatcaa ctttgattta aatattttta aaatagttga
     2281 taagaaagtt tttgaacaac aacacagctt tagattcata gttttcgcta aaccatgaaa
     2341 gatttaaata tcttttaaat tcaatatctt tgatatgtaa caacttaatc tcagggtctt
     2401 gagataatcc ccatgatttt ccacatataa atccaactcc ttgaagtgat tttataagag
     2461 cataaattgt atatggtgaa tcagactcaa atgctatttt gggtttgaaa ttagctgatt
     2521 cgcacaggat atcaattacc tctctataat tctcaccctt cgttataact ataaagtttt
     2581 catctgaaac ttcgcttaga tatacttcat cctttaatga taaaggatgg tttattgaaa
     2641 ctcctaatag tatttcttcg catgttaaag ttatgctatt ttctgagttt agctttgtaa
     2701 atgaagaaga tatgtacaaa tcaaaatcac tttttttata agatgatggc aaagtatgtg
     2761 acacattaaa agtaatattg ggatatagtt ttctgaaatt actcaaaagt gatggtaaca
     2821 cattagccgc tgcaggagat aatatcttta cttctcctga attttctaaa gaagtgtctt
     2881 gtaactcctt ttttgaactt tctactaaat ctaaaatgct atctactctt tttagaaaca
     2941 atcttccata ctcatttaaa acaatatatc ttccttttct gtcaaataac tgaactccaa
     3001 gttctttttc taaggaagat atagttttgc ttaaagctgg ctgtgctata tttaacttgt
     3061 gtgatgcttt tgttatgtgc tccattctag caacagtttg aaaatactta agatgcaata
     3121 aatccatagt ataaaataca cctcttttaa tatgacttga gttatatcaa ttttataatc
     3181 aactccacat tatacattat aatataaagt ttatataata aactacaata tattaaaaag
     3241 ttatttaaat tgttatttat attttgtaca taatctaatt aaaaaaagta actttaaatg
     3301 attaactaag gaaatgttgt tacaaacttt agttatataa aaaattcatt tgatgagcaa
     3361 agtactaata tcaagtaaga ataaaagctt attagataag aaaaataata ttttataata
     3421 atgatgttac ttaaattatt atgttatact attttaaata ggaaaaattt agatactata
     3481 attttagggg gagtcaagat gaaattaact aaatcaatat catcaatgct gtgcttatct
     3541 ctagttttaa gcttatcacc agtagcatat gcaaatgaaa taagtagaac aacagttgag
     3601 aatactttag taggtcagga tagatatcaa actgctgttg aagtaagtaa aaaaggatgg
     3661 agtagtgcaa atgaggctgt agttgtaaat agtgaatcta ttgtagatgc attagctgta
     3721 acaccatttg ctaaattaaa aaatgctcct atattattga cagaaaaaaa taatctaaat
     3781 tcacaaactg agaaagaatt aaaaagatta ggagttaaaa aagtttatat aattggtcta
     3841 tctagttctg tatcaaatga tgtgcaaaaa cagttagaat ctaataattt aactactgat
     3901 agagttggtg gtagtgatag ataccaaaca gctttgagta tagctaaaaa aatagaagga
     3961 ttaaaagata tatcagaaat agctgtagta aatgggtaca caggtcttgc agatgcagtt
     4021 agtataggtt ctgtagctgc tactaatgga atggttatac ttccagtatc tgatgcatct
     4081 ggtatatcta gctttaaaga ttttatagaa tctaagaata taaataaatc atacataata
     4141 ggctctacta atgctgtatc agataaaata aaacaaagtt tacctaattc agaaagaata
     4201 ggtggagcag atagaaatga aactaatggt aaagtaatag aaaagtttta tacatctaat
     4261 aaattaaaca atgtatttgt ggctaaggat ggaatgaaaa atcaaaatca acttatagac
     4321 gctctagcag taggagtact agcatcaaaa gaaaattctc ctgtactaat cgtaggagaa
     4381 caattaagtg caacacaaaa gagtgtattt tcgaataaaa atgctacctc tataactcaa
     4441 gttggtagtg gaggaaatga aaatgcattt aaagaattaa aagatttaca ggcaaatagt
     4501 aacaataaga gagtaatgta tgtaactaat acagataagg taaatataag aaatgatgct
     4561 acaatagaag cttctgttat aggatatcta aataatggtg atgaagtaga agttttagat
     4621 gtgttaaaaa ctggatgggt aaaaataaaa tacaatgaag gtattggata tgttagtggg
     4681 tcttatttga caaataataa gcctgataat agtaatgaaa atataaaaat aaagtatgta
     4741 aaagaaaaag atggtctaaa tgttaggaaa ggaccaagta cagaagatga aaaaataggt
     4801 cacctttcat atggaagcaa agtagaaaca atagaaatgt ttgctactgg atgggtaaaa
     4861 ataaagtaca atggtggata tggttatgta agtaatgatt acttatctga tacaccagtt
     4921 atttaattat aagtaacaat aaaaaaactg ctttaatttg taaagcagtt tttttataaa
     4981 aatttaagtc taataactat ttctattttg ataccttaat cctgggattt attattatgg
     5041 atattatcaa catacaaaca ctccaaatcc agtgtctaat tccaaactta gatattaata
     5101 aattcagtcc tgctatggta aataagcagt atttaattac aattaaaagt gtatttatag
     5161 aaagccccct catagaaagt atcctaaatc caataataga cattctaagt cctataaatg
     5221 ccaataatat acctgcaata tcctgaatta agtaatagta ttcaaatttc atattcaatc
     5281 aactcttctc tgagcagtat caaatatttc taactcttca atttcatcat ctgtgtatgt
     5341 aagcatagta aaaccagtta caccataaat aaatgaaatt ataggtgtaa tccaacttaa
     5401 gaaacaatat ggaataaatt ctagtggact tacaccaaga gtctgagcac agaaaacagc
     5461 atttgaattc catggtatta atggaccacc aagtgtagct gtatcttcta taattctaga
     5521 tagattttgt ggttttaatt taaattcttt gtatattgga gacattagag ttccgacaaa
     5581 tacagaagtg aacatcattg atgaactaaa tgcatttgca aagtagctta ctataaaagt
     5641 agacccaacc aatttagttc ttgattttcc tattttagtt ataagaggtt gaagcagtac
     5701 ttctaagaat ccagtttttt ggagaatacc agcaataacg aaaactacaa atactagtaa
     5761 aacggtttca gccatactca ttattccacc acgatttaat agtttgtcgg catagacaaa
     5821 tccagtatct atagtaaatc ctgatagcat gtaatttaaa acatcaccta ttttttctcc
     5881 ttcttgaaat actgctataa taagtcccat gatagctgaa cttagtatag atataatggg
     5941 tggcttttgt agcaataaaa gtaataataa aaatattatt ggaatcattg ctactaaacc
     6001 aatatgaaag tttgaattta atacatcctt gatttgattt atttgaacat agtctatagt
     6061 attatttgaa tacttaaatc caattactgt atacagaact atacatatta cgtatgcagg
     6121 tcctgtggta taaaacatat gcttcatatg tgtaattaca tctgtcttac aaactgctgc
     6181 agctaagttt gtagaatctg atagaggtga catcttatct ccaaagaaag caccagaaat
     6241 gactgcacca gctgttaaac caagaggaat acccatacta gtaccaatac tcatcattgc
     6301 tataccagaa gttccaagag tcccccaaga tgtaccagta gcaacagaag ttaatgaaca
     6361 tacgattaat gttgtaagca gaaaatattt aggggttatt attgttagtc cactatatac
     6421 tactgttggt attgtaccag cagctatcca agctgctatt agtacaccaa cagaaagtat
     6481 aattaagttt gattgaaagg catctttgcc aacttcaaat ccaaaagctt ctatttcatc
     6541 attagtataa ccaagtttca tggctgcagg aactactata agccatgaaa gtaaaaacat
     6601 tgtagttata gaagcattaa atacaactat accaactgat gttagagcta ttattgcaag
     6661 cattactaac aaggaatatc taaatgaagg tatttttctt tctgtattca ttttcatagt
     6721 gcaaattctc cttaaatatt tttagttaat tgcatttttt attcttataa gagcttcttc
     6781 aagcatactt cttggacaag ctaagtttat tctttgatac ccacttcctc caatgccaaa
     6841 gctgtttcct tgatttagag caactttacc tttttgtaca agtatacttt ctagttcctc
     6901 atcacttaat ccaagtgcac taaagtctac ccataataaa taagtacctt ctggttttct
     6961 aactttaagt tttggcatat tttcatttat atattttata gcaaaatcta tattagattc
     7021 taaatattct aaaaatgatt ctagccaaga ttcaccatta ttatatgaag cttcagttgc
     7081 aactaagcta aagcaattat ttctctttat atcaattctg gtaaaggcat catctaacaa
     7141 tttatagtat ttttcatcag gtagtattac atatgatgat tgaagaccag ctatattaaa
     7201 agttttagtt ggagccatac aagtaattgt atttttttca aattctttag aaatagatgc
     7261 cataggaata tgcttatgtt tttttaatat aatgtcacta tgtatttcat cagatatgat
     7321 ttttacatta tgcttaagac aaatatctcc tagttttttt aattcatctt ttgtccatac
     7381 tctaccaact ggattatgag gattacaaag tatgaataat tttacatctt taatcttgtt
     7441 ttcaatgtct tcataatcca ttatgtagtt tccattttct aatttttgta atgggcttat
     7501 aattagttct ctattgttat tttttacaac actattaaaa gggctgtaaa ctggttcttg
     7561 tatcattatt ttatcatttg cttttgtgag ttcatttatt aaaagactta tagctgggat
     7621 aacacctgga ctataaatta accactcact ttttattttc cagttatgtc tcctatctag
     7681 ccagtttact atagattcat tgtaagaatc tggtcttgtt gtgtagccat aaatctcttg
     7741 ttctagtcta ttttttaaag aatcaattat acaaggtgca gccttaaaat ccatgtcagc
     7801 cacccacata ggaagtaaat cattagttcc atactttttt tccatttctg accatttaga
     7861 tgaaaaatta ttgcttctat caacaatctc attaaaatta taattcattg taaatacctc
     7921 cagtaatttt aattttatgt taataatatt aagcaaacaa cgtgccaata ttgataataa
     7981 aaaatattta ttcacaagtt aatatttaat attaagtaat ttcagagcat agataagata
     8041 aaaatattaa ttatacttaa aactttgtgg aaaaggttat ttctaataaa tttttaaata
     8101 tatgaaaatg taattaaata ggttaaatag gtttaactgt ttaacttgtt agacctattt
     8161 atatttttta gaaactctac tccctttgat gttataattg aacctccacg accaacaagt
     8221 atgtctacaa gcccaaagtc ttgtagttct aaaagcatat ttctaatctg ttgttctgtc
     8281 aaaaatctat tttcctctaa agctatttta cataagcttt ttctacctat tctttctttt
     8341 aaatcataag ccttttttaa attatccaat ataaatatgt attcatctag tgacctttta
     8401 aaattatagt cgtatttcat gatgtttttg tctttgccaa tgttgaattg atactttttt
     8461 atattattac ttactttatt acaaacggtt ctactataat ttgaatctat agtatctaat
     8521 atatattcag gtaaatcaca tatttctata atatcttttt ccaagtaaca gaaatattct
     8581 cctaagtttc ttaattctct tacatttcct tcccatctat acattttaaa gatttctttt
     8641 acttcctcac ttagaataaa attacatgga atatcatatt ttaatgaacc aaaaatttca
     8701 aatatatcag caggtctttc cctaagtgga tgtattttaa ggggaagaac attcaaccta
     8761 aaatataaat ctcttctaaa catattttta gatacaagtt cttttaaatt tctattagta
     8821 gctgcaatta ttcttacatc aatgtcaatg acattattag aaccaatacg tcgtacttgt
     8881 ttttcttgta tgactctaag taatttagat tgagaattta aatccatttc tccaatttcg
     8941 tctaaaaata tagttccatt gttggctaat tcaaataaac caattttccc acctttttta
     9001 gcaccagtaa aagccccttc atcatagcca aataattcac tttgcagtag attttcttga
     9061 aaagtactac aatttactgc gacaaaagga ccatcttttc tcctagaagc actatgaatg
     9121 gattgagcaa ataattcttt accagtacca ctttcaccaa ttataaggat agatgaattt
     9181 gattgagcca ttttattagc aatttttttt gtattaatag tttgtatact agaacctaat
     9241 atatcatcaa atgtgtattt actgatatta ccagagttta ctagttgtgc tcttaattta
     9301 gcttgctttt tttctaattg agaaaacttt gtcatcttta gtataaatcc atcaaataca
     9361 tttaattgta tatgtttaat ctctaaattt atatcaatat gatttatttt aatcaatttc
     9421 tcaaaaaatg gagttttatt ggtcaatatg ctttgaaaat tgatgtcttt tatgcaatca
     9481 ccaacaaatg agtcaatcat ttcatttgca tttatagaca aaatttttct agccatatga
     9541 ttatagaatt gaattattcc atcgttattt gtgcatataa ttccatcatc aattatagat
     9601 agtaacaaat caaattgtct ttcaaactta tttgcatcta acaataactc acctgtacta
     9661 taacttgtag gaattatttt ttctacgtat ttttttatta ggtcatcttt tattagatgt
     9721 tttaatttgg tttttgtagc aatttcaaca atacaactta aatctattat tctgtatttt
     9781 aaatctataa cttcacaatt tttaaactta ggcaagattt tttcgccagg agttaggatt
     9841 acagcatctg tgggagtaaa ctcaatctct ggatagcagg gcaggatatt tatattgtct
     9901 attcctaatc tatgtattaa agaaattgtt tctattgcca tatctttact taagttatat
     9961 acataaataa ttttatcttt ttctaatttg gatatcatat caatactgtt cttttcaaat
    10021 gtcaacttag gaacaatgat ttgagcatca tagtgagata attttactat ttcatcatat
    10081 tttaaataag cagataggag tataagtttt tctttaaaaa actttaaatt tccttcttca
    10141 aatgagtata aatttatctt tagattatca cctaagaatt gtcttatttg attttcataa
    10201 atttctccag cgtctttttt taaacttaca atagctaatt ccatttgttt cattttaacc
    10261 tctcatacaa atttgactta ttttagatta cataataatt aaattagatt aaataatatt
    10321 atttaattat tattataaat ttattataga ctacacattg aagtaaaaga agtagctaaa
    10381 attattcctt ttatttttgt tttttgtatc tatttggtat aatagtatta gagcgtataa
    10441 taatttaggc aaaatttttt aaggaagact agaggagaat ataaaatgaa aaaatgtctt
    10501 tactgtaata gggatataaa gtcaccaaat aataaattag ctataaaata tgatgacaat
    10561 atgaatatat atccatgtcg tgcagaatgt aaggaaaaaa ttgaagaata tatagcaaaa
    10621 aaacctacat ataagtttat aaatatatta gaggttcttt taggtgtggg cggaatattc
    10681 tgctttttga gtaaatggac tattgcagcc caagttgtac ttggaattga tgcactggtt
    10741 atatttttat tcccattggc aggatttaag atgaatggaa agttaagtat ggaacaaact
    10801 aagaatcaaa gtaggtctat tgcaatatca attttggcat ttatagtaat aataactgta
    10861 ttatatttta aacaaattgg taagtagagc ataattgtat aagacatcat tagagtatga
    10921 ggtgagttta tggaagaaag aaaattagca ccaaacaatg agagggaagc tctcataaaa
    10981 agattaaaaa gaatagaagg tcaagttaag ggtatacaaa agatggtgga acaagaacgt
    11041 tattgtgttg atatattggt tcaaatatct gctataaggt ctgctataaa tagagtaggc
    11101 acaattatct tagagaatca tataaaagga tgtgtagcag aaagcattaa acatgatgat
    11161 gctgataaaa ctgaagagat gataaaagag cttatggata ctataaataa atttacaaaa
    11221 taaggaggcg gttagttatg aatcaacaag gatttattat ggaaattgtt gatgatagaa
    11281 ctgcaaagtt aaaaatgcaa agacattcag cttgtgctgc ttgtggaaaa tgtgctacta
    11341 caaattcagc agagtcaaaa gaaatattag tagaagtaga caacacaatt ggcgcaaaag
    11401 ttggtgacca tgtagaagtg agtatggata atatgaatgt attaaaagca gctgtaatgg
    11461 cttatataat acctcttata gcacttcttg taggaacaat agggacttat tatatattgg
    11521 gggcaattgg aatgacaact ggagttgaag ccataagtgg attagttgga atttgtctta
    11581 caataatctg ttatttatac ttaaagaaga atgacaaaaa atttagagac agtagagaat
    11641 ttataccagt aataacaaga atattaattg acctttaaga taattataat taaaaaatag
    11701 caatgtgctt cttaaataaa tactcaatac gtatttgtag agtttaagta cattgctatt
    11761 tttatatttt tattttgatt ttctgtaagg aataaagttt tttctgattt tcaaaagatt
    11821 caatgttctt acaaaagaag ttacaactaa tacaccaagt gctattgcag cacttagaaa
    11881 tagcgcatct gtaccttttg acatagccaa agaataattt ttctgaatca aagacaacat
    11941 tgtattatat agcccaattc ctggtattag aggaagaata cctggaatta cgaacacaat
    12001 agctggttgc tttagttttc ttgctaaagt ctcactgcac gctgagacca aagcagcagc
    12061 gataaaacct gcaaaaactg catttgtagt aaaattaaat aaataaacat atacaatcca
    12121 accaattccg ccagttactc cagctggaag aagtagatat agtggagcat taaagaaaac
    12181 agcaaatcca gcagttgcaa cacctgaaaa taaaaaatgc aaaatcatag acatatcagt
    12241 cattagaaag gacctcctat tctataccat gtatcaagga caaaaccaac tccagaagca
    12301 attgcaataa taatcatagc agcatcaaaa gcacgagaaa ttcctgatat taaattccct
    12361 gatattaaat ctctaatagc ttttataaaa gcaactcctg ggagtagtgg cattatagcg
    12421 ccgactataa gcattttagg gtcatctaaa atgcctattt caactagtag aactcctgaa
    12481 agtgcaatta aaaaagaaga tactaaacag gaaaatgcag atattgcact tatcttcatc
    12541 gttttatcat aagtaattgc agcaaagatt gctattataa acgtaagtat aaaatttaat
    12601 acataattcc ctccaagcaa acaagcaaaa caagcagatg caattcctgt acaagagtaa
    12661 aataaccata aaggataagg ttttacatct tggatttcat aaagacgtgc aatggcatta
    12721 tcaatatcat actctttgtc actaacaaat tctcgagaaa aactgtttaa taaagaaatc
    12781 ttatttaagt ttatacctct tgattgaatc gttttcataa acgaaaagcc atcaaatttc
    12841 tcatctgaaa taattattac tgtaggagtt gtaaaaatat ttacatgata aaaccctctt
    12901 gacctgcata ttctaaggac actgtcttca accctagatg tttcagctcc attttttatc
    12961 atcagttccc ctacaaatag agctagtttt agaatatttt tcttatattc aagttcctca
    13021 ttttgattca taaatacacc tccaaattaa aaaacgtaat attgaaatta tatcaaattt
    13081 ttaagtaata ttccttaata tctatacaaa tatattatct tttttttgtt tcaaaatagt
    13141 cacatttaaa ttatatccaa ttaaaagaat tagacaatat tatttattat attttaactt
    13201 aaaaataaag aaagtaacta tgttaaatat ggaaaaatgg caaaacactt gactattaat
    13261 tggtaaagga ctataataat aaattatcat attgataaaa acgaaaatta tgaaatgtct
    13321 gtaaaaataa aatttaaata ataactagga ggagtaatat gtttgagaac ttgaaaaaag
    13381 cggaccctga gatttatgaa agtatgaaaa gagagttaaa aagacaacaa agaaatattg
    13441 aattaatagc atctgaaaac atagtatcag ttccagtaat ggaaactatg ggaagtcatc
    13501 ttacaaataa gtatgcagaa ggttactcag gcaaaagata ttatggtgga tgtgaataca
    13561 tagatgaagt tgaaactctt gcaatagata gaatcaaaaa aatatttgga gcagaacatg
    13621 ctaatgttca acctcattct ggagcaaatg caaatattgg tgtatatttt gctatgttaa
    13681 aaccaggtga tgttgttatg ggaatgaatt tatctcaagg tggacattta actcatggtg
    13741 ctccagttaa tatttctggt caatattata aattttatga atatggtata gataaagaca
    13801 gtggacttat agattttgat gaagttagaa agatagcaca tgaagtaaaa cctaaaatga
    13861 tagttgcagg agcaagtgca tatcctagag aaatagattt taaaaagttt agagagatag
    13921 ctgatgaggt tggagcattg cttatggtag atatggctca tatagcaggt cttgtggctg
    13981 ctggtcttca ccaaaatcca tgtgaagtgg ctgattttgt tacaacaaca actcacaaaa
    14041 ctttaagagg acctcgtggg ggtgttattc tttgtaaaga aaaatatgct aaagacatag
    14101 acaaagcaat attccctggt attcaaggtg gacctcttga acatataatt gcttctaagg
    14161 cagtttgctt taaagaagct ttaagtgatg agtttaaaga atatcaggta caagttgcta
    14221 aaaatgcaaa agccttagct gaagaactta ttaaaagaga ttttaaattg atttctggag
    14281 gtacagataa tcatttaata ctattagatt tgactaataa aaatataact ggtaaagcag
    14341 cagaaaagag attggatgat gcttatataa cagctaataa aaatacaatt ccatttgacc
    14401 caaatggtgc tcttgttaca agtggaataa gacttggtac tccagctgta actactagag
    14461 gtatgaaaga agaagatatg gcaataatcg ctgaggctat agacctatgt ttaacttatg
    14521 atgaagaatc taaggctaga acattggttg ttggtttaac tgaaaaatat cctttatatg
    14581 aagaatataa tattatggat taattataaa gaacaactaa ataaaataca tttaaataat
    14641 tacaatgatt gtgtatgtat ttgaatatat ttagatataa aaaaggtgtc tcaaaatgaa
    14701 ctttttagtt tatgaggcac ttttttgtat ggaatcgaac atatttgtat tatttaaata
    14761 ataaaaaata tggttatctc tatttttaga tggtctcttt gtatttttta attaaaactt
    14821 taagatttct taagaattat actaggtttt tctaaagatt taaagtctat acttataagt
    14881 atagtaatca tatgaaaaga aaagctttaa cgaggaggga atcttatgaa ggtattaatt
    14941 cttacaggaa aatttggtat gggtcattac tcagcatcaa attctttaag tgaagatata
    15001 aaagcaaaat ttgataattc agaaataata attaaagata tatttgagta cattatgcct
    15061 aactattcag ataaaatgta caagactttt tctattcttg taaatcgggg aagtagtctt
    15121 tataatttgt tttataaatg tgctgaaaat ggaaagaaag atataaaatt tactttttca
    15181 gattattttt taaataaatt agatacatta cttcatgaag tacaaccaac agtagttatt
    15241 tcaacttttc cattttgttc tcaattagta tcaagatata aggaaaaata taactcaaat
    15301 cttcctttaa taacatgtat aactgatata agtagtcact cagaatggat tagtaaaaat
    15361 acagactgtt atttagtagc tagtaaatct actaaggaag aacttgtttt taaaggaata
    15421 gatgaatcta agattaaagt taatggtatt ccagtaaaaa aagaatttaa aagaatagaa
    15481 catgtaaatc attcaactaa aaaaaatatt cttataatgg gtggaggatt aggattactg
    15541 cctaaatcag aacaatttta caaagaatta aatagtttag aaggagtaaa aactactgta
    15601 ataactggta ataataaaaa aatgtactat aaactatatg gtagatatga aaatatagag
    15661 gtagtaggtt acaccaatga agtatataaa tatatgaaag attctgacct tattatttct
    15721 aagccaggtg gaataacact atttgaaaca atttattcag aacttccaat attggcattt
    15781 aatccatttt tacaacaaga gatagataat gctagtttta tattaaataa tgaaattggg
    15841 agaatacttg gtaaaaataa aaaatactat gtagatgaga taaaagattt aatttatgat
    15901 gatgctactc ttaaagaaat gagcagtaac atgaaagaat taaaaaaaca atttgataat
    15961 aataccttag agaatatttt attttcactt gatgaacaag gagcgtgtag agaatgtatg
    16021 tagtaggttt aattatcgtt gttgcattga tttttttagt ccattcaatt atacctacat
    16081 actataataa actattaaat aaagaggtat taaaaaatat ggctggagaa aatgaaattg
    16141 cacttacatt tgatgatggt ccagataaga gatatacaga aaaattacta gatgtgttaa
    16201 aagaaaatga tatacaagct atgttttttg tagtagcaaa gaatgctgaa aaagagcctg
    16261 aaattataaa aagaatgttg agagaaaatc atatagttgg tttacattca ttggaacaca
    16321 gaaatgcatg gctttatagt tatagttatg ttaaaaaaga ttttattgaa agtacaaata
    16381 taatgaaaaa tttaggtgta gatgtaaact actatcgtcc accatggggt catactaata
    16441 tattttcaaa ttcatttgtt aaaaaatata atctaaaaat gactttgtgg gatgtaatgg
    16501 cagaagattg ggagaaagat agtacagtag acattattat aaacaagtta atgagtagaa
    16561 caaaagaaaa ttctataatt tgtttacatg atgcaggtga aaattcaggt ggtgcagtag
    16621 gtgcacctga gcgtactatt gaagctttaa agatagctat tccaaaactt aaagccagtg
    16681 gtttaaagtt cgtaacacca gaaaggatgt agttatgata agtaaaactg aaaagaaaaa
    16741 taaatgccta ggtagtgtag cttttttagt tttactaatg ggcataacag gatattttgt
    16801 ttttagaggg cagtcagttg aatcattgat aaaatcatta aaaggtgcaa gccctatgtt
    16861 tatactaatt ggatttgcaa tgatgtttat atatgttgcc tgtgaaggta taaatatata
    16921 cttaggtatg aaagctttaa accaaaagac tactctttta aaatgtatgg gatatgcttt
    16981 tattggattt tattttagtt ctattacgcc ttcagcatca ggtggtcaac cagcacaagt
    17041 ttattatatg aaaaaagacg atataaatat atcatattct tcacttatac tattagtcat
    17101 tgttgttatt caccaagtag ttatactggc atatagtgga ataatgttca ttatggaacg
    17161 tgagtttata ttaaataatg taagtggtat gaacatttta ctaatatatg gtgtaataac
    17221 aaatgttgct cttgtcattg gagtaattgc aattatattt tcaaaaaaac ttgtaaacaa
    17281 ttttataata tcaataacaa atttattagg taagttaaga ataataaaag atgttgaaag
    17341 ttcaagaaaa gttataatat ctcaaattga agagtatgtt aaaggtgctc aatatataaa
    17401 gcagaatcca aaacttgtag tccaaatttt agtcataact attgtacaaa taacatctat
    17461 gtttttagtt cctttctttg tatacaaagc ttttcatcta tcaacatata ctgtatttga
    17521 gatattagcg atacaatcct tgcttaatat tgctgtttct tcattaccat tgccaggggc
    17581 tgttggagct tctgaaaata gttttatgac attatttaag atatttttcc ctggtcactt
    17641 attagttccg gcaatgttac ttagtagggg aataagtttt tatgcatttg tagctataag
    17701 tggattgata tgtatagtag tacatgtaaa atcttctgaa aaagtaaaag cagtgaaaaa
    17761 agttgcttat gtaagataat attatataga ttatttttat taatatgtca atttgtgtgt
    17821 atattttaat taagctttaa acatgtttac aggagtagaa actattaaaa cgtgtgacat
    17881 tgctaagctt ttgctaataa agtataatat tttatatagt ttgaaatatt taagaaatat
    17941 agcaaaaaaa ggagcttggt gatgaataaa gagattccaa aaaaaatttt agtagctgat
    18001 gataatcctg agattaggga aatcgtagaa atacttttaa ctggtgaagg ttatgaagtt
    18061 attatggcaa cgaatggaga agaagctgta aacttagtag atagtacgat tgatttgatt
    18121 attttggatg ttgtaatgcc tgtaaaaaca ggatttgttg catgtaatga aattagagaa
    18181 aaaacgacag caccaatatt atttttaact gcaaaaactc aagactctga taaagttatt
    18241 ggattttcag caggaggaga tgactattta tcaaagcctt tttcatattc tgaactaatt
    18301 tcaagggtta agtcgctact tagacgttat tatatatacc agggaaagga aaaggaaaga
    18361 gagccaaata tattaaaaac aaaagagtta tgtgtcaatt tagatactca agatgttaca
    18421 ctaaatggag aacctgtgtt tttgacaact atagaatata gtatattaat tcttatgttg
    18481 aaaaatagaa aaaaagtttt ttcgtctgaa aatttatatg aaactatttg ggatgagcag
    18541 tatttttata cagcaaataa tacaataatg gttcatatta gaaatttaag aaaaaagtta
    18601 gaaaaagacc aaaaaaatcc acaatatata aaaaccgcat ggggaaaggg gtattatatt
    18661 gattaacaaa attaagccat ctaagttggg agttatacta ttgatatatg tagtaatctc
    18721 agctgcagtg gctttcattt taaatatacc attttactct gctgttgaat ctatagtaaa
    18781 agatgtatca gaagggaaag tatattttaa aagagaagta aatcaactta tggataattt
    18841 tcaaacttat gtgaataaca atggtataag agcagatgat ggagatgata tagcaaaatg
    18901 gaatagtgat aattggtttg tttctatgaa gatatataaa ggaaataagg ttttttatga
    18961 tacattatac tatcctaatg aagtacctga taagagtgag gaaaatgagt tttatagcag
    19021 tcccatggct agaaactatg agatacaatt ttctgatatt aaagctaata tagttgtagt
    19081 agctttattt agatttagat ttcaaaattt tatagaagca atttctatta catttatggc
    19141 acttacattt attataacat ttttactgtt gtttagtaga aagataaagt acctaaggaa
    19201 aatagaaatg ggtataaaga tagtagagag tggcagttta aagtatagaa tcccagtaaa
    19261 aggtaatgat gaattatcat cacttgcatc tagtattaat gagatgagtc atacattgga
    19321 gaatcaactt ataaaagaaa gggagatgaa gaataaaaat aaagatatag taacttcgat
    19381 atcacatgat gttagaactc cattaacgtc agtaatttgt tatttagatt tgattaaaga
    19441 ccataaatac aatagtcctg agcaattgga acaatacata aaaaatgtaa ggtctaaagc
    19501 atatcaaata aaagatttaa cagatgacct ttttacgcat tttgttaatt ctggagagga
    19561 agtttcaaaa gggtatgaaa aaataaatgc taatgaattt atttttcaat tacttttaga
    19621 tagttcatat acattggagg agaaaggatt tcatataaca atagaaaatg aactttataa
    19681 ccaatatcat atttatgtag atgttacaca atttagaagg atatttgata atttatgttc
    19741 taatataata aaatatgcta ggaaagataa gcctatagta tttttaatta aagtagagga
    19801 ttctaaatta ctaattatac aaaaaaatag agtaagtaat ttttctaaga atgtagaaag
    19861 ttttggaatt ggtataaaga attgtgagaa aatagttgca tatcataatg gaagcataaa
    19921 tgtaaattca gatgataaag aatttgctat tgaaatatct attccagcaa aagaatcata
    19981 aaaatttaaa ttatatattg tgtaattgct attatatatt gtgtaattgc ttatgtaaaa
    20041 ttctatgaag caggaagcat gtgactttag ttatgggatg ttcaatattg tgtacctcta
    20101 ggcaagtaac aagtttactt acaagaccat ataatattat tatcttaaaa aaaggggaca
    20161 taataatatg gttttgacag gagcacatta tatttacatt ctatttatgg taattatatt
    20221 aattactatg attatgaaaa aggatacaat agtaccatgt atattaggtg ttttttttat
    20281 gggattgttc tttgaaaaaa acatctttgg tgctataaca gcagtgttta actcttttat
    20341 tatatcttta aatgagttgg gtccaattat cttgattata gctattatgg ttgcattatc
    20401 taaagcccta gaagccaata atgctataca gtatatggtg agaccatttt cgagagttat
    20461 aaaaaattct aatacagcat tttttgtaac tggatttgtt atgttagttc tttcttggtt
    20521 tttctggcca actccagctg ttgccttagt tggagctgta tttttacctg ttgctatgag
    20581 agctgggcta ccagcaattg gtgttgcagt agcattaaat ttatttggtc atggtcttgc
    20641 cttatctaca gactttgtta ttcaaggagc tccaagtata acagctggtg cagcaggtgt
    20701 tgcagtatca tatgttataa atgatggtat gattttgttt tgggtgatgg gaatcgtaac
    20761 catatctatg gcattttata cattaaaaag agatattaac aaaggaatgt ttagagaaga
    20821 actaaaaggt tttgaaagtg aagaagtaga agcgttcaat ggaaaatcta aaatagcaac
    20881 tattttagta gctttgggat ttcttgctga tataattgct atgtatgtat ttgacctaaa
    20941 aggaggagat gcatcagctc ttttgggtgg aacagcagta tttttaataa taattataaa
    21001 tgttataaat tttggcaaag atagtcttga aaatgtatgt gagaatataa ttgatggttt
    21061 tgtgtttggg ataaaaatat ttggagcaat tataccaata gcagcatttt tctatatggg
    21121 tgaagttgca ccattgacag gtgtatttgg aaaagtatta gcaccaggtt cacaaggttt
    21181 attatcagat ataggcatag ctctttctca aacaatacca cttaataaat ttgccgtatc
    21241 aggtatagaa actgtagtgg gagcaataac tgggcttgat ggttctggat tttctgggat
    21301 ttcattagtt ggttcacttg cctctgtatt tggaactgct ataaatgcaa gtgttggtgc
    21361 attagctgca ttaggacaaa tcagtggtat atgggtaggt ggaggctgtc tagttccttg
    21421 gggtcttatt tcagcagcgg caatttgtgg ggttagtcca atagaattgg caaagcgaaa
    21481 ctttgtccca gttataaccg gattggttgt aacaaccata gtagcaatgt ttattattta
    21541 ataaatcgaa taaatcttta attgtataaa ttaaaaatag atgtgtagct ataatttatt
    21601 ataattgttt tactaattct aagccataca tctattttta ttgatatttt tattagtatt
    21661 ctttaataaa gtaatatttt tcattatatt atacataaca tctaaatata acatctaaaa
    21721 tactgttatc tatatttaat atcttgccaa attttttgat gttttattgc cctgtcccac
    21781 caacatatat aagctatcac aagtttttac ctatactatc accaaacaaa aattctaatt
    21841 ttaatttatt attttataac ctatattata ttaactatat tagtttgtag actttagatg
    21901 taattataaa tattaatact ccaagagttc aaattcatat cctagttttc ttgcatttga
    21961 tataaaatca tttaaaattt ctgtactagt tttggaaact gcatgtagta acaagataga
    22021 accatcatgt agattatcca ttattttttg cgttgcttct tcatgtgatg gttgtttatc
    22081 agtatcccag tctctgtatg caaaactcca aaatacagtc ttgtatccta aatttttagt
    22141 cattgccaag cttttttctg agtattttcc cataggaggt ctaaaaaatt taaccatatc
    22201 tttcccagtt acatctttat ataacttttc aacatcatat aattcgtcat taaagttttt
    22261 tagattgctt gtttttgttg gcatagatgg atgggtttta ctatgatttc caactatatg
    22321 tccctcagaa accattcttt ttactaaatc tttattttct tttatatatg gagctgtaac
    22381 aaaaaaaact gctttaacct ggttttgttt tagagtgtcg agtatttttg tagtgtatcc
    22441 attttcataa ccttcatcaa atgtaagata tagtgttttt tgaccatctt ttgtaggtcc
    22501 attgtatagg gcatcatagt cagaaaattt aaattcaatg tccgtattta cttctggtgt
    22561 tttatgctta ttgtttggta tataaaacca atcaagagta gtgttatcta aagaagatac
    22621 atctaattta ttattatcat tattagtagt ggcttttgat ggtttatctg ttccgtctga
    22681 aactattaca ttggaagtat ctttaccact atctattttt tccttatctt cttgtaactg
    22741 tgtttcctta ttttgatttt cgttttgatt gttttgtgaa tttgaacatc caacaataaa
    22801 aaaaatagaa atagaaagta gtgttaaata atgcaatact tttctaaaca ttttgaagct
    22861 cctttctaaa ttaataataa ttgcatataa taataattat atgattaatt acaattgcat
    22921 atagtattat tataattgga aattactatt aataatagtt atatctttaa aaataaagtc
    22981 acaatagtat gacaaagggt gaataatcaa taaatttaaa aaaaaatgaa aaaaatagtt
    23041 gaccatatta tgagaagatg ttattataat aaatgtgctc aacaagaagt aacaaaataa
    23101 caagcacaaa gaagttaatt gaat
//
LOCUS       DAEPKC010000061        23103 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.061, whole genome shotgun sequence.
ACCESSION   DAEPKC010000061 DAEPKC010000000
VERSION     DAEPKC010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 23103)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23103)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23103
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.061"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(<1..896)
                     /locus_tag="KR294_002393"
     CDS             complement(<1..896)
                     /locus_tag="KR294_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009243519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HBH0240464.1"
                     /translation="MKLKHIAIIGSLFPILFSIVLFFGVLMSADSDDENSNFSSGITG
                     MNLSAEVLKHQPMVEKYAKEYGISEYVNVLLAIIQVESGGTAKDVMQSSESLGLPPNS
                     LDTESSIKQGCKYFASLLSSCKNQGINDLNVAIQSYNYGGGYVGYVAGKGKKHTFNLA
                     ESFAREKSGGKKVTYTNPIAVAKNGGWRYGYGNMFYVELVNQYLTVPQVSGELAQKVM
                     NEALKYQGWKYVYGGSNPNTSFDCSGLTQWCYGKAGISLPRTAQMQYDATQHIPLSQA
                     KAGELVFFHSTYNAGSYVTHVG"
     gene            complement(893..3085)
                     /locus_tag="KR294_002394"
     CDS             complement(893..3085)
                     /locus_tag="KR294_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBH0240465.1"
                     /translation="MKERIQSAFTKKKIFHFLKMALFVVALSLILLSLLGTVAHATGL
                     VDDTINAENLYSKYPLSNYQLDFYVDNSWAWLPWNWLDGIGKSVQYGLYCITNFVWTI
                     SLYLSNATGYVVQEAYKLDFINDMADSIGQSIQTLAGVTSSGFSTSGFYVGFLLLIIL
                     VVGLYVAYTGLIKRETSKALHAVINFVVVFILSASFIAYAPDYIKKINEFSSDISTAS
                     LDLGTKIMLPNSDSEGKDSVDLIRDSLFSIQVEQPWLLLQFGNSNAEEIGTDRVEALV
                     SASPENEDGKTREEVVKTEIESNDNNNLTIPQVVNRLGMVFFLLFFNLGITIFVFLLT
                     GMMLFSQILFIIFAMFLPISFLLSMIPSYESMAKQAIVRVFNTIMTRAGITLIVTVAF
                     SISSMFYNISTDYPFFMVAFLQIVCFAGIYMKLGDLMSMFSLNANDSQSMGRRIFRRP
                     YLYMAHRARRMERRLAGAVTAGGVAGAVAGSTVSNARTTRNNSAKDNRGNTSSSMGQR
                     AGSKVGAVLDTKNKVKDKANAMKETVKDIPTQTAYAVHSAKEKAKTSVSDFKRGMVQE
                     QQSRQSGRLEKQEQHKKNIADKRMELQKAQEARQARKTDGSATTGATRPHERPVTASA
                     IPKTNVEKTQEVKRPATTSTSKAGEPVKTNSVKERPLSSGTSDGKIPQSAQTVHSKNV
                     EKVVSHETHQNYKAERTTKAQTVEQAKRTTEHTEKNRNLVTKKGQKKK"
     gene            complement(3085..5535)
                     /locus_tag="KR294_002395"
     CDS             complement(3085..5535)
                     /locus_tag="KR294_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH0240466.1"
                     /translation="MFPIKYIDNNLVWNKDNEVFAYYELIPYNYSFLSAEQKFIVHDS
                     FRQLIAQSREGKIHALQIATESSIRSMQEQSKRLVTGKLKEVAYQKIDEQTEALVSMI
                     GDNQVDYRFFLGFKLMVTEEQLNLKNLKKSAWLTFKEFLHEVNHTLMNDFVSMPNDEI
                     NRYMKMEKLLENKISRRFKVRRLEINDFGYLMEHLYGRDGIAYEDYEHQLPKKKYKKE
                     TLIKYYDLIRPTRCVIEESQRYLRLEHEDKESYVSYFTVNAIVGELDFPSSEIFYFQQ
                     QQFTFPVDTSMNVEIVENRKALTTVRNKKKELKDLDNHAYQAGSETSSNVVDALDSVD
                     ELETDLDQTKESMYKLSYVIRVSADDLDELKRRCDEVKDFYDDLNVKLVRPAGDMLGL
                     HSEFLPASKRYINDYVQYVKSDFLAGLGFGATQQLGENTGIYMGYSVDTGRNVYLQPS
                     LASQGVKGTVTNALASAFVGSLGGGKSFCNNLLVYYSVLFGGQAVILDPKSERGNWKE
                     TLPEIAHEINIVNLTSDKDNAGLLDPFVIMKNVKDAESLAIDILTFLTGISSRDGEKF
                     PVLRKAVRSVTQSETRGLLHVIDELRCEDTAISRNIADHIDSFTDYDFAHLLFSDGTV
                     ENAISLDNQLNIIQVADLVLPDKDTTFEEYTTIELLSVSMLIVISTFALDFIHSDRSI
                     FKIVDLDEAWAFLNVAQGEILSNKLVRAGRAMQAGVYFVTQSSGDVSKESLKNNIGLK
                     FAFRSTDINEIKQTLEFFGIDKEDENNQKRLRDLENGQCLLQDLYGRVGVVQIHPVFE
                     ELLHAFDTRPPIQRNEVE"
     gene            complement(5522..5911)
                     /locus_tag="KR294_002396"
     CDS             complement(5522..5911)
                     /locus_tag="KR294_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009274602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBH0240467.1"
                     /translation="MKKIRSYTGIWNVEKVLYAINDFNLPFPVTFTQITWFVITEFII
                     ILFGDMPPLSMIEGAFLKYFGIPAFLTWFMSQKTFDGKKPYSFLKSQITYALRPKITY
                     AGKAVKLQKEIFNETITAVRSVSYVPD"
     gene            complement(6029..6532)
                     /locus_tag="KR294_002397"
     CDS             complement(6029..6532)
                     /locus_tag="KR294_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBH0240468.1"
                     /translation="MIDDMAVYIANLGKYNEGYLVGAWFTFPIDEEDVKEKIGLNEQY
                     EEYAIHDTDNFPIEIGEYVSIDELNEMYEMIEELPDYIVDCLDEFIGHYGTLEEVVEH
                     KDDIYYYPDCETMTDVAYYYIDELQALGDIPPSLQNYIDYEAYGRDLDMGGCFIATSR
                     GMCEIPY"
     gene            complement(6535..7038)
                     /locus_tag="KR294_002398"
     CDS             complement(6535..7038)
                     /locus_tag="KR294_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBH0240469.1"
                     /translation="MQETRVLVETKRTTGEETTSYWFDLPIEVAEFEEKLGVSTESQD
                     YRIIEKLLPYADEVHEHTSVYQLNELDYMYRQLSSDMQEEYTMLHTVYENLEALYICR
                     NVITLYPDCKSMIDVARQKLMNDPTFKHLSEDCQEYYFDFETYASHLQEHGKFLVTEH
                     GIFELPE"
     gene            complement(6957..7253)
                     /locus_tag="KR294_002399"
     CDS             complement(6957..7253)
                     /locus_tag="KR294_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005339688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBH0240470.1"
                     /translation="MNDIFRDMQAKVGCENISDLPSYKRKVWHEMKQLNLADYEEKQL
                     EDFSKYVFGMSCQTLKDVMKQQKGREEQCRKQGYWWKRKEQLAKKQHHTGSTCR"
     gene            complement(7350..7952)
                     /locus_tag="KR294_002400"
     CDS             complement(7350..7952)
                     /locus_tag="KR294_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBH0240471.1"
                     /translation="MDKVVIYIHGKGGNAEESSHYKPLFSDCDVVGLNYTAQYPWEAK
                     EEFPSLFDLICKHYKSVQIVANSIGAYFAMNALSDKQIEKAYFISPIVNMEKLIADMM
                     YWANVTEDELRDKKEIKTTFGETLSWEYLCYVKENPTTWKIPTNILFGEKDNLTSYAT
                     ISEFTKQTNATLTVMRNGEHWFHTEEQMKFLDEWINKSAR"
     gene            complement(8037..8198)
                     /locus_tag="KR294_002401"
     CDS             complement(8037..8198)
                     /locus_tag="KR294_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240472.1"
                     /translation="MAIVVIGIYLGFKREFSKLIGFLVVALVAVGLVFNAGGVKDVLL
                     ELFNKIIGA"
     gene            complement(8365..10275)
                     /gene="ltrA"
                     /locus_tag="KR294_002402"
     CDS             complement(8365..10275)
                     /gene="ltrA"
                     /locus_tag="KR294_002402"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HBH0240473.1"
                     /translation="MPKNKNETLCVEDLRHAEYYEMQNTFDDLYAKSKNGDIFTHLMD
                     IILSRENILLAYRNIKANAGSKTAGTDGTIIKDIGKLPAETVVKKVRYIVAGSPHGYR
                     PKPVRRKEIPKPNGKTRPLGIPCMWDRLIQQCIKQVLEPICEAKFSENSYGFRPNRSV
                     ENAIKATYNRLQISQLHYVIEFDIKGFFDNVNHSKLIKQIWAMGIRDKHLIFILKRIL
                     KAPIKMTNGTITYPEKGTPQGGIISPLLANIVLNELDHWVESQWQENPVTKNYVVHIN
                     KSGSPCKSNAYKEMKKTKLKEMYMVRYADDFRVFCRYKESAEKAKIAITQWIEQRLKL
                     EVSQEKTRIVNVRKRYSDFLGFKIKMIPRRKKLVVKSHISDKQFKNQKDKLVSQAKKI
                     ASPSKGKTELEETRLYNSMVLGMQNYYQIATNVNLDCMKLNRAVMAIFTNRLGTNKRG
                     RLRKTGRQLTTKEATRYGKSKMLRYVAGEGEPIFPVGYIQHRKPMAKVYLANCYTLEG
                     RKFIHTNLSVDKLLMYQLMKLSLENRTIEYADNRISLFSAQHGKCAITLEEFQQANEI
                     HCHHIVPTGAGGNDDYKNHILVKEAVHRLIHAKTEETIQKYIALLKLNKVQLIRLNKY
                     RVLAGNQELNLI"
     gene            complement(11017..11151)
                     /locus_tag="KR294_002403"
     CDS             complement(11017..11151)
                     /locus_tag="KR294_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017143882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HBH0240474.1"
                     /translation="MWELLKDLLLVSFGMGIGVVLMCILTVGKEADRCMEEIKEREDN
                     "
     gene            complement(11159..12358)
                     /locus_tag="KR294_002404"
     CDS             complement(11159..12358)
                     /locus_tag="KR294_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HBH0240475.1"
                     /translation="MNETDFLTALKEKRCAYGVSQTRLAIMANISREHLSRIEAGKVT
                     LTEDMKHTLLEAVEKFNPNNPMFLLFDYVRIRFPTMDIKHIIKDILKLNIGYMLHEDY
                     GHYKYTEHYHIGDVFVYVSQDEEKGVLLELKGKGCRQFESYLLAQERSWYDFFTDALV
                     EGGVMKRLDLAINDRTGLLDIPELIRKCENEECISKFRSFKSYGSGELVKHNETDKYG
                     MGHTLYIGSFSSEVYFCCYEKNYEQYAKLGIPIEEVPIKNRFEIRLKNERAYYAVVEL
                     LTHYDAELTAFSIINQYIRFADKEPDKRKSDWKTNVRWAWFIGEGRPPVKLTTQPEPY
                     TLERTLNWLQRQVAPTLKMLKQIDKDNQTEYLETIEKQAKLTERHYQIIKQQTATVEE
                     MVANVKE"
     gene            complement(12560..13954)
                     /locus_tag="KR294_002405"
     CDS             complement(12560..13954)
                     /locus_tag="KR294_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008787614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH0240476.1"
                     /translation="MKMILNKGHRIRASDKNLVYHFSIGTLLFVFIAVILLLNMKQLM
                     RTDWEHFSLLDNGLTLSTYNFITLLIATGVCALVAFLYYRFCYDSFKKLLHRQKLARM
                     ILENKWYEADTVQDSGFFTDLQSRSREKIIWFPKIYYQMEKGLLHIRCEITLGKYQDQ
                     LLRLEDKLESGLYCELTDKTLHDGYIEYTMLYDMIANRITIDEVKAENGCLRLMKNLV
                     WEYDALPHALIAGGTGGGKTYFLLTLIEALLHTNAVLYILDPKNADLADLGTVMGNVY
                     HTKEEMIDCVNAFYEGMVQRSEEMKRHPDYKTGENYAYLGLPPCFLIFDEYVAFFEML
                     GTKESVSLLSQLKKIVMLGRQAGYFLIVACQRPDAKYFSDGIRDNFNFRVGLGRISEL
                     GYGMLFSSDVKKQFFQKRIKGRGYCDVGTSVISEFYTPLVPKGHDFLQTIGSLAYARQ
                     DGTATCEAKGDGTD"
     gene            complement(14071..14556)
                     /locus_tag="KR294_002406"
     CDS             complement(14071..14556)
                     /locus_tag="KR294_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006776881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240477.1"
                     /translation="MAKEKGSFKEFLSAIAPEHQAFVEKLNTKLIEQGCDLVIKEAKS
                     GYTASYQLEKKTVMNWVFRKTGVFARIYGDNAGKYEDIIASLPADMQKKMTTSRDCKR
                     LIDPNACSDTCVKGFVYALNGDTHKKCRNDGMLFVLTNETAEHIAGLVCAEVNVRKSA
                     L"
     gene            complement(14654..15037)
                     /locus_tag="KR294_002407"
     CDS             complement(14654..15037)
                     /locus_tag="KR294_002407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014080829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBH0240478.1"
                     /translation="MRLANGIVLDKEKTFGVLKFSALRHEVRAENDDGSTSEEITRRT
                     YDLKCSVQERMIQVSIPADIPVKDYPYNAEVELVNPVADTVANASYRGVNVDWYIKAD
                     DIILKNKGGQVGNPQNHAPQGQPKK"
     gene            complement(15052..15378)
                     /locus_tag="KR294_002408"
     CDS             complement(15052..15378)
                     /locus_tag="KR294_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005337695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBH0240479.1"
                     /translation="MELKYVVPNMAQTFGNLEFAGENKIEQQRINGRFTPVSRSYNLY
                     SDVQRADDIIVTIPAKAGEKHFKPEQRVKLINPKITADGKAVKGRGFTNYILTADDML
                     PAEESK"
     gene            complement(15614..18658)
                     /locus_tag="KR294_002409"
     CDS             complement(15614..18658)
                     /locus_tag="KR294_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SrtB-anchored collagen-binding adhesin"
                     /protein_id="HBH0240480.1"
                     /translation="MKKILKRLCTGVLAFATVVTALPTTLVHAESKQYWTESEERVGI
                     VEKVMNDGSIGSTFNEGHLTVEGEDAYCIDINTDFKNGYKTRADASSRMSADQISDVA
                     LSIEYVKQYTDNHNGISKNHAYLLRQLVVWQRLSVHLGWQCDNVRASYDEIPKATQDE
                     VFAGAKAFVKENKGRYECGGYIYSGEGQELGQFWAKLNVGNAKLQKTSNNTSITNGNG
                     NYSIAGATYGVFSDKDCTKQIATLTTDDSGNTEVAEVKATTVYIKELSAPLGYKVDTT
                     VYSLKVEAGKTATLKVSDTPKVTDTLIELFKIDMETQKANPQGNASLEGAEFTWKYYA
                     GFYNKDNLPAEATRTWVTKTTAETDSNGTTHYITKLADAYKVSGDSFYMQDGKAFLPL
                     GTLTVEETKSPTGYLLDGAYMQANGSEEQIKALYLTQITEDGDLAVLTGSNQFSVSDK
                     VIRGGVKIQKRDLETKDTKPQGSATLKDTAFDIISLNDNAVLVEGKIYKKNEVVKTIH
                     TDIEGIASTSADLLPYGNFRIVEKQAPNGYLTDGAKPIDFTITENGKIVDLTDEAHSI
                     YNQIKRGDIEGVKIGAGTHKRLADVPFRITSKTTGESHVVVTDDNGQFSTSSKWASHK
                     HNTNAGKTSEDGVWFGTSEPDDSKGALPYDTYIIEELRSDSNKGMELIPPFEIVVSRN
                     NLVIDLGTLTDEYEKEITIHTTATSKDGEKTILAGKEVTIVDTVKLDGLTKGTKYQLK
                     GWQMLKEENAEIIIDGKRVESDYTFVADDEEMKVEISYTFNASELGGKNLVTFEELYD
                     LSNPDEPMKVAEHKDIEDDGQTVLITERIIKIHTTATDKDGNKELEAGKDVTIIDTVT
                     LEGLEVGTKYKLVGWQMLKEENAELLINGKRVESDYTFIADSETMKVEVTFTFDATSL
                     DGKQLVTFEELYDLSNPNEPKKVTEHKDIEDEGQTITFKEKPEVPEKPETPTTPEKPS
                     RPTDSPKTGDNTNVMAFLVMLLTSAGGLAGTYLYKRRKMKKS"
     gene            19186..20193
                     /gene="asrA"
                     /locus_tag="KR294_002410"
     CDS             19186..20193
                     /gene="asrA"
                     /locus_tag="KR294_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfite reductase subunit AsrA"
                     /protein_id="HBH0240481.1"
                     /translation="MKLKLDSSKFNEGLNYLKKDYKIFAPVLIPFKGTFSDTDVIRYK
                     EVNAFEEMEFAKKANFSPKDVVLPINQVLFYFTEKEFKESDLDNKKILIFLRACDING
                     IKRLDEIYLNNGEEKDYFYKNIRDKVKFALVGCKESFRNCFCVSMDSNKTDNYSIGLN
                     IEGDTLYLDIKDSEFEVFNGEATEFNVDYVTDNLISVDVPENIDSNEMIGNSIWDEYD
                     TRCIGCGRCNFVCPTCSCFTMQDIFYKENENVGERRRVWASCQVDGYTDIAGGNSFRK
                     KQGERMRFKTMHKIHDFKKRFGYHMCVGCGRCDDACPQYISFSKCIEKINDLVISKEE
                     V"
     gene            20194..20985
                     /gene="asrB"
                     /locus_tag="KR294_002411"
     CDS             20194..20985
                     /gene="asrB"
                     /locus_tag="KR294_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfite reductase subunit AsrB"
                     /protein_id="HBH0240482.1"
                     /translation="MNPYIPVSAKILDIVKHTDKEWTFRVNCNTKGVLPGKFYEISIP
                     KYGESPISVSGYGEDYIDFTIRNVGKVTSELFNYKEGDSFFIRGPYGNGFDVSLYEGR
                     EIVVVAGGSALAPVRGIVEYFYNNKEKCEKFKLIVGFKSPKDILFADDLKRWSKKLDI
                     LVTVDGAEEGYSGNVGLVTKYIPELDMKDINNTSIVVVGPPMMMKFTVEEFLKRDLDE
                     KNIWVSYERKMCCGIGKCGHCKMDDTYICLDGPVFDYSYAKNLID"
     gene            20998..21969
                     /gene="asrC"
                     /locus_tag="KR294_002412"
     CDS             20998..21969
                     /gene="asrC"
                     /locus_tag="KR294_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite reductase subunit C"
                     /protein_id="HBH0240483.1"
                     /translation="MIRDLNTKKVMKNAYRITKTKYETSLRVRVPGGLIDPESLAVVS
                     KIASEYGNGQVHITTRQGFEILGINMEDMEEINKIIQPVIEKMNINQSEKNAGYPAAG
                     TRNIAACIGNKVCPKAQYNTTEFAKRIEKAIFPNDLHFKVALTGCPNDCIKARMNDFG
                     IIGMALPIYEKDRCVNCGACVKKCSKISVGALKTENNKVVRDKDKCIGCGECVLNCPT
                     NAWTRDEKKYYRLAIMGRTGKKNPRLAEDFLLWVDEDSIIKIILNTYRYVEKYIDKDA
                     PGGKEHIGYIIDRTGFMEFKKWALEGVELPEITKMYENIYWSGIKYL"
     gene            22026..22802
                     /locus_tag="KR294_002413"
     CDS             22026..22802
                     /locus_tag="KR294_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HBH0240484.1"
                     /translation="MHKETLDKLTNAAINKINLLNTSKVKYLVSSAFAGLYVGIGILL
                     IFTIGGLLTDAGSPMTKIVMGLSFAIALSLVIMTGTELFTGNNMVMSAGMLNKGVSIK
                     DTSKIWAYSWVGNLIGALVLGIIFVGTGLVDKGPVAEFFANTAASKASMPFTALFFRG
                     ILCNILVCVSVLCSFRTNSDTAKIIMIFLCLFAFITSGFEHSVANMTIYSVSLFSPTI
                     STVTIGGAIYNLVAVTLGNIVGGALFMGLGTYILGKEKLN"
BASE COUNT         6525 a         4656 c         4318 g         7604 t
ORIGIN      
        1 attcccacat gggtaacata cgaaccagcg ttataggttg aatggaaaaa gaccaactcc
       61 ccagcttttg cctgcgataa agggatatgc tgggttgcgt catattgcat ttgtgccgtt
      121 ctcggtaaag agataccagc ttttccataa caccattgcg tcagtcccga acagtcaaag
      181 gaagtgttgg gattgctacc gccatacaca tatttccagc cttgatattt caacgcttca
      241 ttcattacct tttgtgccag ttctcccgat acctgcggaa cagttaaata ctgattgact
      301 aattccacat aaaacatatt tccatagcca taccgccagc ccccattttt cgcaacggct
      361 atcgggttgg tgtaggttac ttttttaccg ccagatttct cacgggcaaa gctctctgca
      421 aggttaaaag tatgtttctt tccttttcct gccacatatc ccacatagcc accgccatag
      481 ttataggact gtatcgccac attcaaatca tttattcctt gatttttgca ggaagaaagc
      541 agggacgcaa aatatttaca cccctgcttg attgagcttt ctgtatctaa cgagttgggc
      601 ggtaaaccaa gactttctga actctgcatg acatcttttg ccgtaccgcc actttctact
      661 tgaatgatag ccagtaacac attcacatac tcagaaatac cgtattcttt agcgtacttt
      721 tccaccatag gctgatgttt caagacttct gcggataaat tcatacccgt aatgcccgaa
      781 gaaaagttgc tgttctcgtc gtcgctgtcc gcactcatca gtaccccaaa gaaaaggact
      841 atggaaaaga ggataggaaa cagactgcca atgatagcga tatgtttcaa tttcattttt
      901 tcttctgtcc tttcttcgtt acaaggttac ggttcttttc agtatgttct gttgtacgct
      961 ttgcttgttc aactgtttgt gcctttgtgg tacgttctgc tttgtaattc tggtgtgttt
     1021 catgcgatac cactttttct acatttttac tatgtactgt ctgtgccgat tgtggaattt
     1081 ttccgtcaga tgtacccgaa gataagggac gttctttcac actatttgtt ttgactggct
     1141 cgcctgcttt ggaagttgaa gttgtagcag gacgtttgac ttcctgtgtt ttctcaacat
     1201 ttgtttttgg aatggctgaa gctgtgactg gtcgctcatg gggacgggta gctcccgttg
     1261 tcgctgatcc gtccgtcttt cgtgcctgcc ttgcttcttg tgctttttga agttccatac
     1321 gcttgtcagc gatattcttc ttatgctgtt cctgcttttc caagcgtccc gactgtctgg
     1381 attgttgttc ctgcaccatg ccacgcttga agtccgatac acttgttttt gctttttcct
     1441 ttgcggaatg gacggcataa gcggtctgtg tcggtatatc cttgaccgtt tctttcatag
     1501 cgtttgcctt gtctttgacc ttattcttcg tatctaagac agcacccacc tttgaaccag
     1561 cacgttgtcc catgctggaa gatgtattcc ctcggttgtc ttttgctgaa ttattccttg
     1621 ttgtccttgc attagaaacc gtactgccag ccaccgcacc agcaacaccg ccagcggtaa
     1681 cagcaccagc aagccgtctt tccatacgcc tagccctatg tgccatataa agatacggtc
     1741 tgcggaaaat tcttcgtccc atgctttgac tgtcgttagc gttcaaagag aacatactca
     1801 ttaaatcgcc taacttcatg tagataccag cgaaacacac tatctgcaag aacgccacca
     1861 taaagaacgg gtagtctgtg gaaatgttat aaaacatact ggaaatgcta aatgccaccg
     1921 ttacaatgag cgtaattcct gcccttgtca ttatggtatt aaataccctc acgattgcct
     1981 gctttgccat gctttcatag ctcggtatca tggatagtaa aaagctgata ggtaaaaaca
     2041 tggcgaagat aataaaaagt atctggctga acaacatcat acccgtaagc aagaatacaa
     2101 atatcgtgat acctaagttg aagaacaaga ggaagaacac catacctaaa cggtttacga
     2161 cttgcggtat cgtcagattg ttgttgtcgt tactttcgat ttctgttttc acgacttcct
     2221 ctctggtttt gccgtcctcg ttctctgggc ttgccgatac aagagcttct acacggtctg
     2281 tcccgatttc ctctgcgttg ctgttcccaa actgtaagag tagccacggc tgttccactt
     2341 gaatagagaa taggctgtcc cttatcaagt ccacgctgtc cttgccctcg ctgtcagagt
     2401 ttgggagcat gatttttgtt cccaagtcca aagaagcggt actgatgtcg cttgaaaatt
     2461 catttatctt tttgatgtag tcgggagcat aggcaataaa tgaagccgac aaaataaaca
     2521 ccacaacaaa gttgataacg gcgtgaagtg ccttgctggt ttctctttta atcagtcccg
     2581 tataggcaac atatagtccc accactaaga taatgagaag caggaaaccg acatagaagc
     2641 cagaggttga aaaaccgctt gaggtaacgc ctgcaagggt ctgtatgctc tgcccgatac
     2701 tgtctgccat atcattgatg aagtccagct tgtaggcttc ctgcactaca tagcccgtgg
     2761 cattacttaa atataaactg atagtccaga caaaattagt gatacagtac aaaccatatt
     2821 gtactgattt tccaatcccg tccagccagt tccacggcaa ccaagcccag ctattatcca
     2881 catagaagtc aagctgatag ttggaaagcg gatatttgga atatagattt tctgcgttta
     2941 tcgtatcgtc cacaagcccc gtcgcatgag ccaccgtccc cagaagtgaa agcaggataa
     3001 gggagagtgc caccacgaac agagccattt tgagaaagtg gaaaatcttc ttttttgtga
     3061 acgcactctg tatcctttct ttcatcactc cacctcattt ctctgtatag gcggtctggt
     3121 atcaaaggcg tgtagcagtt cttcaaagac ggggtgtatc tgtaccacgc cgacacgccc
     3181 gtataagtcc tgcaacaagc attgtccgtt ctccaaatca cgaagtcgct tctgattgtt
     3241 ttcgtcctct ttgtcgatac cgaaaaattc taaagtctgt tttatctcgt tgatgtcagt
     3301 agaacggaaa gcgaatttta agccgatatt gtttttcaga ctttcctttg acacgtcccc
     3361 agaagattgc gtaacgaaat acacacctgc ctgcatagct cgtccagcac gcaccagctt
     3421 gttagataaa atttcgcctt gtgccacatt taagaacgcc cacgcttcat caaggtctac
     3481 gattttgaag atagagcggt cgctgtggat aaaatctaag gcaaaggtac taatcacaat
     3541 cagcatggaa accgatagta attcaatggt cgtgtattcc tcaaaagtcg tgtccttatc
     3601 tggcagtaca aggtcggcta cttgaatgat attgagctga ttatctaaac tgatagcatt
     3661 ttccaccgtt ccgtctgaaa acagaagatg tgcaaaatca tagtctgtaa agctgtcgat
     3721 atggtctgcg atattgcgtg aaattgcggt atcttcacag cgtaactcgt ctatcacatg
     3781 aagcaagccc cttgtttcac tctgggtaac agaacgcacc gccttacgaa gtacggggaa
     3841 tttttcgccg tccctagagg aaataccagt taaaaaggtt agtatgtcga ttgccagact
     3901 ttcagcgtct ttcacattct tcataatcac aaacgggtca agaagccctg cgttgtcctt
     3961 gtcgcttgtt aggtttacga tattgatttc atgggcgatt tctggaagtg tttctttcca
     4021 gtttccacgc tctgattttg ggtctaagat aaccgcttga ccgccaaaca aaacagaata
     4081 gtacacaagc aggttattac agaatgactt cccaccgcca agcgaaccaa caaaagcaga
     4141 agcaagggca tttgtaactg taccttttac gccttgactg gcaagggacg gttgcagata
     4201 tacatttctt cccgtatcaa cggaatagcc catatagata cccgtgtttt cccctaactg
     4261 ctgtgtcgca ccaaaaccaa gcccagctaa gaagtctgat tttacatact gcacataatc
     4321 attgatatat cgcttgctgg ctggtagaaa ttcagaatga agccccagca tatccccagc
     4381 aggacgtact aacttcacat tcaaatcgtc ataaaaatct ttgacttcat cacaacggcg
     4441 tttcagttcg tccaaatcat cagcagacac acggataaca taagagagct tatacatact
     4501 ttcttttgtc tggtctaaat cggtttccag ctcgtccacg ctgtctaaag cgtctactac
     4561 atttgagctg gtttcacttc cagcttgata agcgtgatta tcaaggtctt tcagttcctt
     4621 tttcttgttg cggacggtcg ttaatgcttt tcggttttcc acgatttcta cattcatgct
     4681 cgtatcaacg ggaaaggtaa attgctgttg ctggaaatag aagatttcac tagacggaaa
     4741 atcaagctcg cctacaatcg cattgacggt aaaataggac acataacttt ccttgtcctc
     4801 atgttccaat cgtaaatatc gctggctttc ctcaatcaca caccttgtcg ggcggataag
     4861 gtcgtaatac ttgataagtg tttctttctt atactttttc tttggtagct ggtgctcata
     4921 atcttcatag gcgataccgt ccctgccgta aagatgttcc ataagatacc caaagtcatt
     4981 gatttccaga cggcgaacct taaagcgacg ggagatttta ttttccagta acttttccat
     5041 tttcatgtaa cggttgattt catcattcgg catggaaaca aagtcgttca tcagcgtgtg
     5101 gttcacttca tggagaaact ctttgaacgt cagccacgcc gattttttaa ggttcttcag
     5161 attgagctgt tcttccgtaa ccatgagttt aaagccaaga aaaaagcggt agtccacttg
     5221 attgtcccca atcattgata ctaacgcttc ggtctgttcg tctatcttct ggtaagcgac
     5281 ttcctttaat ttccccgtaa ccaatctttt tgactgctcc tgcatacttc ttatagagct
     5341 ttccgtggca atctgcaaag catgaatttt accctcacgg gactgtgcga ttagctgtcg
     5401 gaaactgtca tgcacgataa atttctgttc tgcggataag aaagaatagt tatacggtat
     5461 cagctcatag taggcgaaca cctcattgtc cttgttccag acaaggttgt tgtcaatata
     5521 tttaatcggg aacataactc acactcctta ctgccgtgat tgtttcgttg aatatttctt
     5581 tttgcagttt tacggctttt cctgcataag tgattttcgg tcgcaacgca taggttatct
     5641 gtgatttcaa aaagctgtat ggcttctttc cgtcaaaggt tttctgcgac ataaaccaag
     5701 tgaggaaagc aggaataccg aagtatttta aaaatgctcc ctcaatcatg gaaagtgggg
     5761 gcatatcccc aaacagaatg atgataaatt ctgtaatcac aaaccatgta atctgtgtaa
     5821 aggtaacggg aaagggcaag ttaaagtcat tgattgcata caagactttt tctacattcc
     5881 agatacccgt gtagcttcta atctttttca agttctttca actcctctca taagtttcta
     5941 aatggaaaag gacagccctg tttcagactg tcccttaaag agaaatacgc cgtcagtagc
     6001 aacaatgctt gtcgctgatc ttccagcgtt aatatggtat ctcgcacatt cctcggcttg
     6061 ttgcaatgaa gcaaccgccc atatccaaat ctcgcccgta tgcttcatag tcaatatagt
     6121 tctgcaagct agggggaata tcgccaagtg cctgcaattc atctatgtag taataggcaa
     6181 catctgtcat ggtttcacag tcgggataat agtaaatatc gtccttgtgt tccacgactt
     6241 cctccagcgt cccataatga ccaataaatt cgtccaaaca atccacgata tagtcgggaa
     6301 gttcctctat catttcatac atttcattga gttcatcaat ggaaacatac tccccaatct
     6361 caatcgggaa gttatcggta tcatggattg cgtattcttc atactgttca ttcaagccga
     6421 ttttttcttt cacatcttcc tcgtcaatag ggaaagtaaa ccaagcaccg actaaatagc
     6481 cctcattata cttgccaaga ttagcgatat aaactgccat atcatcaatc atacttactc
     6541 tggcaattca aagataccgt gttccgttac taaaaatttc ccgtgttcct gcaagtgtga
     6601 agcataggtt tcaaagtcaa aatagtattc ttgacagtcc tcggataaat gtttgaatgt
     6661 agggtcattc atcagctttt gccttgcaac atcaatcatg cttttacagt cgggataaag
     6721 cgtaattaca ttcctgcaaa tataaagtgc ttctaaattt tcatacaccg tatgaagcat
     6781 tgtatattct tcctgcatat cgcttgaaag ctggcgatac atataatcta attcattgag
     6841 ctggtacacg cttgtatgct catggacttc atcagcataa ggcaacaatt tttcaataat
     6901 gcggtaatct tgactttctg tactgacacc taacttttct tcaaactcgg caacctctat
     6961 cggcaggtcg aaccagtatg atgttgtttc ttcgccagtt gttcttttcg tttccaccag
     7021 tacccttgtt tcctgcattg ttcctcacgt cctttctgtt gtttcatcac atcttttaaa
     7081 gtctggcatg acataccaaa cacatatttt gaaaaatctt ctaactgttt ttcttcatag
     7141 tcggcaaggt tcagttgctt catttcatgc cacaccttac gcttgtaaga gggcaggtct
     7201 gaaatgtttt cacaaccaac ttttgcctgc atatctctaa aaatatcgtt cattacatca
     7261 ctccaatctg aaatttaggt aagaaaaaag cagtcaatcc taagactaac tgctttgtgt
     7321 gtatggatat gaagttgtca aactgggatt tatctggcag acttgtttat ccactcatca
     7381 agaaatttca tttgttcttc cgtgtgaaac caatgctctc cgtttctcat aacagtaagt
     7441 gttgcattag tttgttttgt aaattcagat atagttgcat aagaagtcaa gttatctttc
     7501 tcaccaaata aaatatttgt tggaattttc catgtagttg gattttcttt tacataacag
     7561 agatattccc atgagagtgt ttctccaaaa gttgttttaa tttctttttt atctcgaagt
     7621 tcatcttctg taacatttgc ccaatacatc atatctgcaa tcagtttttc catattcaca
     7681 ataggtgaaa taaaatatgc tttttctatt tgcttatctg ataaggcgtt catagcgaaa
     7741 taggcaccta tgctatttgc aactatttga acagatttgt aatgtttgca aatcaaatca
     7801 aaaagtgatg gaaattcttc ttttgcttcc catggatatt gtgcagtata gttgagtcca
     7861 accacatcac aatcactaaa aagaggtttg taatgtgaag actcctctgc atttccacct
     7921 ttaccatgta tataaataac tactttatcc ataatagttg tcctcctcaa cttcaaattt
     7981 gtcgctttct tcatatccac attatatcat tctcatatca gcaccacaat aaaattttac
     8041 gcaccgataa tcttattgaa cagctctaac agtacgtctt tcacaccgcc agcattgaat
     8101 accaatccaa cggcaacaag ggcaactacc aagaagccga taagtttaga aaactcacgt
     8161 ttgaacccta agtagatacc aataaccaca atcgccataa gcactaagct ctgggcgttg
     8221 cttaaaaacc atgtgtatat ggataggtaa gttcctgata ttataaatat ctcaaacttt
     8281 tccccccatt cacacggagc gtgcgacttt caacgcactc cgcgttccat cgtgtttata
     8341 ttgaaaagta tttatgtagt agacctatat caagtttaat tcttgattgc cagctaatac
     8401 tctatattta tttagtctta tgagctggac tttatttagc ttcaatagag ctatatattt
     8461 ttgtattgtt tcttctgttt tagcgtgtat tagacggtgt accgcctctt ttaccaaaat
     8521 atgattttta taatcgtcat ttccaccagc tccagttggt acaatatgat gacaatgtat
     8581 ttcattagct tgttgaaatt cttccagagt tatagcacat tttccatgtt gagcagaaaa
     8641 tagcgaaatt cgattgtctg cgtattctat tgtgcgattt tccaaagata atttcattaa
     8701 ctggtacatc agtaatttat caacacttag attggtgtgg ataaattttc ttccctctag
     8761 agtgtagcaa ttcgctaaat acacctttgc cattggtttt ctgtgttgga tatatccaac
     8821 agggaaaata ggttcgccct cgccagcaac ataccggagc attttagatt taccatatct
     8881 tgttgcctcc tttgtcgtaa gttgtctgcc tgtttttctc aatctgcccc ttttgtttgt
     8941 acctaatctg ttagtgaaga tagccattac agctctattc agtttcatac aatccagatt
     9001 tacattcgtt gcaatctgat aataattttg catacctaat accattgaat tataaagtct
     9061 tgtttcttct aattccgttt tcccttttga gggagaagca attttctttg cctgtgatac
     9121 cagcttgtct ttttggtttt tgaattgttt atcacttata tgtgatttaa caactaactt
     9181 ctttcttctc ggtatcattt taatcttgaa accaagaaag tcggagtatc tttttctaac
     9241 atttacaatt cttgtttttt cttgtgatac ttccaatttt aatcgttgtt caatccattg
     9301 agtgattgct attttggctt tttcagcact ttccttgtag cggcagaaaa ctctaaaatc
     9361 atctgcataa cgaaccatat acatttcctt taactttgtt ttcttcattt ctttgtaagc
     9421 gttgctttta catgggctac cgcttttatt gatatgaacc acatagtttt ttgtaacagg
     9481 attttcctgc cattggcttt ctacccaatg gtctaactca ttaagaacaa tgtttgctag
     9541 tagtggggat attattcccc cttgcggagt tcctttctct ggatatgtta ttgtaccgtt
     9601 agtcattttg attggagctt ttaatatcct ttttaaaatg aatatcaagt gcttgtcccg
     9661 tattcccata gcccatatct gttttatcag cttggaatgg ttcacgttgt caaagaaacc
     9721 cttaatatca aattcaatca cataatgtag ctggctgatt tgtaggcggt tataggttgc
     9781 ttttattgca ttttcaactg acctattagg tctgaaacca tagctgtttt cactaaattt
     9841 agcttcgcag attggttcta atacttgttt tatacattgt tgtataagcc tgtcccacat
     9901 acaaggaata cctagaggtc tggttttacc atttggtttt ggtatttctt ttcgcctcac
     9961 tggcttaggt cgatacccat gtggactgcc tgcaacaatg tatcttactt ttttgacaac
    10021 tgtttctgct ggcaatttgc caatatcttt aattattgta ccgtctgttc ctgctgtttt
    10081 actgcctgca tttgctttga tatttcgata tgccagtaat atattttctc tcgataggat
    10141 aatatccata agatgagtga aaatatctcc attcttactt ttggcatata aatcatcaaa
    10201 ggtgttttgc atttcgtaat attcagcgtg tcttaaatct tctacacaca atgtttcatt
    10261 tttattttta ggcataaggc ttcactcctt tgcttgaaat tgagtgagct tttttatctt
    10321 actcgtaatc cttattgaaa caacataata cttttctaat atatacacga cttgagggca
    10381 ttcctccatt ctcattacaa gaatttctta ggttcgccct ctgcttttca gcattagttc
    10441 aactgcttat tgttcttcgt cagtttattc tcttgatgag aacccaatac ctttcctcgt
    10501 tccgataatc ttatctatac atatatatcc ttaggtcact agctataagc ctgctggctt
    10561 gataccgcct gtaacgttat atggcatttc ataacctata ttcttacttt gccacaccag
    10621 ctacgatttc tcgtaccttt gcatttctac aaagttcaaa tttagacccg tacattcgct
    10681 gtttcgtcag ttccttatag aacattctaa ccatagatat tttatagacc cccgacctgt
    10741 tggatacgct acccgcctct ggatagtttt cgatagaaga tatatgttca tcaactatta
    10801 cggtatcttt cagccgtctt taccaagctt caaacattct gagtttcctc atacaatgct
    10861 tgtcggaggc tcagggcagg cgtttcagag cgttacttca tcattccacc tgtcagatta
    10921 tcagttctcc taataaccaa actttttcgt tcttttatta gtgccttagc ttttcactaa
    10981 ggaacgagtc gcacataaat tttgtccgaa attcatttaa ttgtcctctc tttctttgat
    11041 ttcttccata catctgtcag cttctttgcc gacagttaaa atgcacatca agactacacc
    11101 gatacccatt ccaaatgata ccagcaataa gtctttcaat aattcccaca ttttttcatc
    11161 actcctttac gttggcaacc atttcttcaa ccgtggctgt ctgttgcttg attatctggt
    11221 agtgtcgttc ggtcagtttt gcctgctttt caatcgtttc cagatactcc gtctgattgt
    11281 ccttgtctat ctgcttcaac atcttcaagg tcggtgcaac ctgcctttgt agccagttga
    11341 gtgtacgctc cagcgtgtaa ggttctggct gtgttgtcag ctttacgggc ggtcgcccct
    11401 cgccaatgaa ccaagcccag cgtacattgg ttttccagtc gctttttcgc ttgtctggtt
    11461 ctttatcagc gaagcggata tattgattga taatagaaaa tgctgtcagt tctgcgtcat
    11521 aatgtgtcag cagttccaca acagcataat aggcacgttc atttttcaaa cgtatctcaa
    11581 atctattttt tatggggact tcctcaatcg gtatgccaag tttggcgtac tgttcgtaat
    11641 tcttttcata acagcagaag tacacttcac ttgaaaatga accaatatac agcgtgtgtc
    11701 ccataccgta tttatccgtt tcattatgct ttaccagctc tccagaacca tagcttttga
    11761 aagaacggaa tttagaaata cattcctcat tctcgcattt tcgtatcagc tctggaatat
    11821 caagtaagcc cgttcggtca ttgattgcca aatcaagacg cttcattaca ccgccctcaa
    11881 ccaatgcgtc cgtgaagaag tcataccaac ttcgctcttg tgccagcaga tagctttcaa
    11941 actggcgaca gcctttgcct ttcagttcca gcaggacacc tttttcttcg tcctgcgata
    12001 catacacaaa cacatctccg atatggtaat gctcggtgta tttgtaatgt ccgtaatctt
    12061 cgtgaagcat atagccgatg ttgagcttca atatatcctt gatgatatgc tttatatcca
    12121 ttgtgggaaa acggatacgc acataatcaa acagcaggaa catgggattg ttgggattga
    12181 atttttccac cgcttctaaa agcgtatgtt tcatgtcctc ggtcagcgtt acctttcctg
    12241 cttcgatacg gctcaaatgt tcacggctga tatttgccat gattgcaagc cttgtctgcg
    12301 atacgccgta tgcacagcgt ttttctttca aggcggttaa aaaatcagtt tcattcagtt
    12361 gtcatacccc caatcgtgat aattttgtga tattgtgata atttcaaggc tttatcacaa
    12421 aaggcgaaat gtacgaaaaa cccttatttc atgcggtctt gcaaaggttt ttgtggaagt
    12481 ttccgccgta attgtgcccc tctgttagat aatgaggggc ttgtatctgc tggcgtggct
    12541 aacgccacac cagcaacggc tagtccgtgc cgtcgccttt cgcttcgcac gtcgccgtcc
    12601 cgtcctgcct tgcgtatgca agtgagccta tggtctgcaa aaaatcatgt ccttttggaa
    12661 ctaagggtgt gtaaaattca cttatgacgc ttgttcccac atcacaatag ccacgtccct
    12721 tgatacgctt ctggaaaaac tgttttttca catcagaact gaacagcata ccgtaaccta
    12781 attcgctgat acgccccaag ccaacacgga aattaaaatt atctctgata ccgtccgaga
    12841 aatattttgc gtctggacgc tggcaggcaa caataaggaa atatcctgct tgtcgtccta
    12901 acatgacgat tttctttagc tggctaagta ggctcacact ttcttttgtc cccagcattt
    12961 caaaaaacgc cacatattca tcaaagataa gaaagcaggg cggtaaacca agataggcat
    13021 agttttcgcc cgttttatag tctgggtgtc gcttcatttc ttcgcttctt tgtaccatgc
    13081 cctcataaaa ggcattgaca caatcaatca tttcttcttt ggtgtgatac acatttccca
    13141 ttaccgtacc taaatctgca aggtcagcgt tcttcgggtc taatatgtaa agaacagcgt
    13201 tcgtatgtaa cagagcttca ataagcgtca gcagaaaata cgttttaccg ccaccagtcc
    13261 caccagcaat cagagcgtga gggagtgcgt catattccca tacaagattt ttcatcagcc
    13321 taagacagcc gttttctgct ttcacttcat caatggtaat gcggttcgct atcatatcat
    13381 aaagcatggt gtattcgata taaccgtcat gtaacgtctt gtcggtcagc tcacaataca
    13441 agccactttc caatttatcc tctaaccgta agagctggtc ttgatatttt cctaatgtaa
    13501 tttcacagcg gatatgaagc agtccttttt ccatttgata ataaatcttt ggaaaccaga
    13561 tgattttttc ccttgatctg ctttgcaggt cagtaaaaaa accgctgtct tgtacggtgt
    13621 ctgcttcata ccacttgttt tccagtatca ttcgtgccag cttttgacgg tgcaggagct
    13681 tcttgaaact gtcataacag aagcggtaat acagaaaagc gaccaatgca caaacaccag
    13741 tcgctatcag tagggttatg aagttgtaag tggaaagcgt caaaccgttg tctaataagc
    13801 tgaaatgctc ccaatcggta cgcatgagct gtttcatatt cagtagcagg ataaccgcaa
    13861 tgaatacaaa cagaagcgtc cctatggaaa agtggtagac aaggttcttg tcgctggctc
    13921 tgatacggtg tcctttgttt aaaatcattt tcataaatca atcactcctt tctgggtacg
    13981 aaaaaagcag tcaatcctaa gactaactgc tttgtgtgta tggatatgaa gttgtcaaac
    14041 tgggatttat tgttcttaac ttttctgtcg ttataaagct gacttacgca cattaacctc
    14101 tgcacagacc agcccagcta tatgctccgc tgtttcattt gtcagtacaa agagcattcc
    14161 gtcattacgg cattttttat gtgtgtcgcc attcaaggca taaacaaaac cttttacaca
    14221 ggtatcacta caggcattag ggtcaatcag tctcttgcag tcacgagaag tagtcatttt
    14281 cttttgcata tcagcaggaa gcgaagcgat tatatcctca tactttccag cgttgtctcc
    14341 gtaaatccgt gcaaaaacac ctgtcttgcg aaacacccaa ttcattactg ttttcttctc
    14401 tagttggtat gaagcggtgt aaccgctttt tgcttccttt attacaaggt cacagccctg
    14461 ctcaataagt ttggtattaa gtttctcgac aaacgcttgg tgttctggcg cgattgccga
    14521 tagaaattct ttgaatgaac ctttttcttt tgccattatc tttttcctcc acaaatttca
    14581 atttatccgt ttcttcatac acatattata acagttgctt atatccgcta caatgaaaat
    14641 ctagtttgcc agcttatttc tttggttgcc cctgcggtgc atggttctgt ggattgccta
    14701 cttgaccgcc tttattcttc aagataatat cgtcagcctt gatataccag tccacattga
    14761 cacctcgata gctggcgttt gctaccgtat cggctacggg attgacaagc tctacctctg
    14821 cattatacgg atagtccttg acgggaatat cagcaggaat tgatacttgt atcatacgtt
    14881 cctgcacact acatttcaaa tcataggttc ttcgtgtgat ttcttcactt gttgaaccgt
    14941 cgtcattttc tgctcgcacc tcatgtctga gggcagagaa cttcaataca ccgaaagttt
    15001 tttccttgtc taatacaata ccgtttgcta atctcataat catttacccc cttacttgct
    15061 ttcctcggct ggcaacatat catcagccgt taagatatag tttgtgaacc ctcgtccttt
    15121 gaccgcttta ccgtctgcgg taatctttgg attgataagt tttactcgct gttctggttt
    15181 gaaatgcttt tcgcctgctt tcgctggaat ggttacgata atatcatcag ccctttgtac
    15241 gtcagagtac aagttgtagc ttcttgatac gggcgtaaag cgtccgttaa tgcgttgctg
    15301 ttcaatcttg ttttcgccag caaattccaa gtttccaaaa gtctgtgcca tgttcggcac
    15361 tacatatttt aattccatag tgttttacct cgtttctttc ttctttttta agtttgttga
    15421 ttgtgctttc ttattctggg aattagggaa ataccagtaa tcccccagat agtaaagggt
    15481 aaatcaatgc ttcgcaccct tgactatccg tgtgcttgca ggttgttggc agacaagcca
    15541 gaataagtaa acgtctgccg tttgacagct tcggcagaga gcgtgatttt tcttttctca
    15601 taccgttacc gccttatgat ttcttcattt tacggcgttt gtaaagatat gttccagcca
    15661 gtccaccagc agatgtaagc aacattacca gaaatgccat gacatttgtg ttgtcgcccg
    15721 ttttaggact gtctgttggt ctgctcggtt tttctggtgt tgttggcgtt tcgggtttct
    15781 ctgggacttc tggtttttcc ttaaaagtaa tcgtctgtcc ctcgtcctca atgtccttat
    15841 gctcagtaac ttttttcggc tcgtttggat tgcttaaatc atacaattct tcaaaagtta
    15901 caagctgttt gccgtcaaga gaagtagcgt caaaggtaaa ggtaacttcc actttcatag
    15961 tttcgctgtc agcgataaac gtataatcac tttccacacg ttttccattt ataagaagct
    16021 ctgcattttc ttctttcaac atctgccagc ccacaagttt atactttgta ccaacttcca
    16081 agccctctaa ggttacagta tcaatgattg ttacgtcttt tcctgcttca agctctttgt
    16141 taccgtcctt atcggtagca gttgtatgta ttttgatgat acgttctgta ataagtaccg
    16201 tctgcccgtc gtcctcaata tctttatgct ccgcaacttt catgggttcg tctggattgc
    16261 ttaagtcgta taattcctcg aatgttacca gatttttacc gccaagctcg gacgcattga
    16321 atgtataaga aatttccact ttcatttctt catcatcagc aacaaaggta taatcgcttt
    16381 ctacacgttt cccgtcaatg ataatctcgg cgttttcttc ctttaacatc tgccagcctt
    16441 ttaactgata cttagtgcct tttgtaagtc cgtctaattt gacagtatca acgattgtta
    16501 cctcttttcc tgcaaggatt gtcttttcgc cgtctttact ggttgctgtg gtatggatag
    16561 tgatttcctt ttcgtattca tcagtcaaag tccctaaatc aatcacaaga ttatttcttg
    16621 ataccacgat ttcaaatggt gggataagtt ccatgccttt gttgctgtca gagcgtaatt
    16681 cttcaataat gtaagtatcg taaggcaacg cacctttgct gtcgtctggt tcagaagttc
    16741 caaaccatac accgtcctcg cttgttttgc cagcgttggt attgtgcttg tgcgaagccc
    16801 attttgaaga agtggagaat tgcccattat cgtcagttac cacaacatga ctttcgcccg
    16861 ttgtcttgct tgtgatccta aagggaacat cagcaagacg cttgtgtgtg cctgcaccga
    16921 ttttcacgcc ctcaatatcc ccacgcttaa tctgattgta gatagagtgg gcttcgtctg
    16981 ttaagtccac gatttttccg ttttctgtga ttgtaaaatc aatcggcttc gcaccgtctg
    17041 tcaagtaacc gtttggagct tgtttctcaa cgatacggaa attcccgtaa ggcaaaaggt
    17101 cagcagaagt agaagcgata ccctcaatat ccgtatggat tgtttttaca acttcgtttt
    17161 tcttgtatat cttgccctca accaataccg cattatcatt taaggaaatg atgtcaaagg
    17221 cagtatcttt caaagtggca cttccttgtg gtttggtatc tttggtttct aaatctcgtt
    17281 tctgaatttt gacaccgcca cgaatgactt tatctgatac ggaaaactgg ttacttccag
    17341 ttaatacggc aaggtcgccg tcctcggtaa tctgcgtaag gtataaggct tttatctgtt
    17401 cttcactacc attcgcctgc atatatgcac cgtctagtaa gtagcccgtt ggcgatttcg
    17461 tttcttcgac cgttagtgta ccaagaggta aaaacgcttt tccgtcctgc atatagaagc
    17521 tatcgccaga taccttgtat gcgtctgcta attttgtgat gtaatgggtt gtcccgttac
    17581 tgtctgtttc agcggttgtc tttgtaaccc atgtacgagt agcttcggca ggaagattgt
    17641 ctttattgta gaagcctgca taatatttcc atgtaaactc cgccccctct aaagaagcgt
    17701 tcccttgtgg gttggctttc tgtgtttcca tgtcaatttt aaaaagctca atcaaagtat
    17761 cggtaacttt tggcgtatca gatactttca aagtcgctgt ctttccagct tcgactttta
    17821 aggaatacac cgtagtatca actttatacc ccaatggtgc agataattct ttgatatata
    17881 cggtagtagc tttgacttct gcaacctctg tatttccgct gtcgtcagtc gtaagggtag
    17941 caatctgttt ggtgcaatcc ttatcggaaa agacaccgta agtcgcacca gcgatagagt
    18001 aatttccgtt accgttagta atgctggtat tattggaagt cttttgaagt ttggcatttc
    18061 cgacatttaa cttcgcccag aattgcccta attcctgccc ctcgccagag tagatataac
    18121 cgccgcattc atagcgtcct ttgttttctt tcacaaaggc ttttgcacca gcaaacactt
    18181 catcttgtgt tgcctttggt atttcatcat aagaagctcg cacgttatca cattgccagc
    18241 ctaagtgaac actcaatctt tgccacacaa caagctgtct taaaaggtag gcgtgatttt
    18301 tgcttatccc attgtggttg tcggtgtatt gcttcacata ttcgatagat aaggcaacat
    18361 cacttatctg gtcggcactc atacgggagc ttgcgtcagc tctggtcttg tagccgttct
    18421 taaaatctgt gttaatatcg atacaataag cgtcctcgcc ctcaacggtc aaatgcccct
    18481 cgttaaaggt agaaccaatc gaaccgtcat tcattacttt ttcaacgata ccgacacgtt
    18541 cttcactttc cgtccagtat tgcttgcttt ctgcatggac aagtgtagtc ggtaaagcag
    18601 taacgacagt cgcaaaggca agtacgcccg tacacaatcg tttcaatatc tttttcataa
    18661 ttctaaatgc tcctttcatt ttgggtaata aaatagccgt ccataatgaa cggctggaaa
    18721 tagaaaagga acgtcaattt aggcgttcca tagtctatga aatattcaat ttttttcttg
    18781 cttcaatact gatgtgccgt accatatctt tgcatatcta ggaaaacttg cgtatcaagg
    18841 ctcattcatt ggtagtaaat tagtagtaaa ttgatgtgtt tgtttccttg aaaatgctga
    18901 tagatactat gttttagcgg ataatcaact ttttagtatg ttttttgcat aaaaattgag
    18961 tagatagtag ttttattgta cttaatgatt gtatttaagt gattagattt gaaattgaat
    19021 aatgtagata ataaaaaaat attaacagaa cttaataaac tccattaata tttttttatt
    19081 atttttgaaa ctgtgataat tatcacggaa gcatagaaaa taaagtgtta agatttaaac
    19141 aagatagtaa gtaagtaaaa ctaaaatata agaaaggtga taaaaatgaa actaaaatta
    19201 gattcatcta agttcaatga aggtctgaat tatctaaaaa aagactacaa gatatttgca
    19261 ccagttttaa taccatttaa aggtactttt tcagatactg atgttataag atacaaggag
    19321 gtaaacgctt ttgaagaaat ggaatttgct aagaaagcaa acttttcacc aaaagatgtt
    19381 gtacttccca taaatcaagt attgttttat tttactgaaa aagagtttaa ggaaagcgat
    19441 ttagacaaca agaaaatttt aattttctta agagcttgtg acataaatgg tataaaaaga
    19501 cttgatgaaa tatatctaaa taatggtgaa gaaaaagatt atttttataa aaatatcaga
    19561 gataaagtaa agtttgcact tgtagggtgt aaggaaagtt ttagaaactg tttttgtgtg
    19621 agcatggatt ctaacaaaac tgataattat tcaattggat taaatataga aggagataca
    19681 ctgtacttag atataaagga tagtgaattt gaagtattta atggagaagc aactgaattt
    19741 aatgttgatt atgtaactga taatttaata tctgtagatg tgccagagaa tattgattca
    19801 aatgaaatga taggaaattc aatatgggat gaatatgata caagatgtat aggatgtggt
    19861 agatgtaatt ttgtatgtcc aacatgttca tgttttacaa tgcaggatat tttctataag
    19921 gaaaacgaaa atgtaggtga gagaagaagg gtttgggctt cttgtcaagt agatggatat
    19981 acagatatag caggtggaaa ttcttttaga aaaaaacaag gcgaaagaat gagatttaaa
    20041 actatgcata aaatacatga ttttaaaaaa agattcggat atcatatgtg tgttggctgt
    20101 ggaagatgtg atgatgcctg tccgcaatac atatcatttt caaagtgtat agaaaaaata
    20161 aatgatttag taattagtaa ggaggaagta taaatgaacc catatatacc agtaagtgca
    20221 aaaatactag atatagttaa acatactgat aaagaatgga cttttagagt aaactgcaat
    20281 acaaaaggtg tattgcctgg aaagttttat gagatatcta tacctaaata cggtgaaagt
    20341 ccaatatcag tatcaggata tggagaggat tatattgact ttacaataag aaatgtagga
    20401 aaagtaacta gcgagttgtt taattataaa gaaggagatt ctttttttat aagaggtcct
    20461 tatggaaatg gatttgatgt atccctttat gaaggaagag aaattgtagt agtggcagga
    20521 ggaagtgcat tagcccctgt aagaggaata gttgaatatt tttataataa taaagaaaaa
    20581 tgcgaaaagt ttaaattaat agtaggattt aaatcaccaa aagatatttt atttgcagat
    20641 gatttaaaga gatggagtaa aaaacttgat attttagtta ctgtagatgg agcagaggaa
    20701 ggatatagtg gtaatgtagg attagtaaca aaatacatac cagaattgga tatgaaagat
    20761 ataaacaata cttctatagt tgtagttgga cctccaatga tgatgaaatt tacagtagaa
    20821 gaatttttaa aaagagattt agatgaaaag aacatttggg tttcttatga aagaaaaatg
    20881 tgttgtggaa taggtaaatg tggacattgt aaaatggatg atacttacat atgtttagat
    20941 ggaccagtat ttgattattc atatgctaaa aatcttattg attagggggt gaagtttgtg
    21001 ataagagatt taaataccaa aaaagtaatg aaaaatgctt atagaattac aaaaacaaaa
    21061 tatgagactt ctttaagagt tagagtacct ggaggtctta ttgaccctga gagtttagct
    21121 gtagtttcta aaattgcaag tgagtacggc aatggacagg tgcacataac tacaagacag
    21181 gggtttgaaa tattaggaat aaatatggaa gatatggaag aaataaataa aattatacaa
    21241 cctgttattg aaaaaatgaa tataaatcaa agtgagaaaa acgcgggtta tccagcagca
    21301 ggtacaagaa atatagcagc ttgtatagga aataaagtct gtccaaaggc tcaatataat
    21361 acaactgaat ttgctaaaag aatagaaaaa gctatatttc caaatgattt acattttaaa
    21421 gtggctttaa ctggttgtcc aaatgattgt ataaaagcta gaatgaatga ctttggaatt
    21481 attggtatgg ctttaccaat atatgaaaag gatagatgtg taaattgtgg agcatgtgta
    21541 aaaaaatgtt ctaagatatc tgttggagca ttaaaaacag aaaataataa ggtggtaaga
    21601 gataaagata agtgtatagg ctgtggagag tgtgtactaa attgcccaac aaatgcatgg
    21661 actagagatg agaaaaaata ctatagatta gctataatgg gtagaacagg aaagaaaaac
    21721 cctagactag cagaagattt tcttttatgg gtagatgagg acagcataat aaagataata
    21781 cttaatactt atagatatgt agaaaagtat atagataaag atgcaccagg aggaaaagaa
    21841 catataggat atataattga tagaacagga tttatggaat ttaaaaaatg ggcacttgaa
    21901 ggtgtagagc ttccagaaat aactaaaatg tacgaaaaca tatactggag tggaattaaa
    21961 tatctataaa ttgagtaaaa catatatttg aataaattaa aatttaatag aaggaagagg
    22021 gagttatgca taaagaaact ttggataaat taactaatgc agctataaat aagataaatt
    22081 tattaaacac aagtaaagta aaatatttgg tatcttctgc gtttgcagga ctttatgtag
    22141 gtataggtat acttttgata tttactattg gaggactttt gactgatgca ggttcaccta
    22201 tgactaagat agtaatgggg ttatcatttg caatagcact aagtttggtt ataatgacgg
    22261 gaacagagtt atttactgga aacaatatgg ttatgtctgc tggtatgtta aataaaggtg
    22321 taagtataaa agatacttct aaaatatggg catacagttg ggtaggtaat ttaatcggag
    22381 ctttggtttt aggcattata tttgtaggaa ctggtctagt agacaaagga cctgtagctg
    22441 aattttttgc aaatacagca gctagtaaag catccatgcc atttacagct cttttcttta
    22501 gagggatttt atgtaatatt ctagtatgtg tatcagtgtt gtgttcgttt agaactaata
    22561 gtgatactgc aaaaataatt atgatattct tatgtttatt tgcttttata acatcaggtt
    22621 ttgagcatag tgtagcaaat atgacaattt atagtgtttc attattttca ccaacaataa
    22681 gtacagttac tattggagga gctatttata atttagtagc tgtaacactt ggaaatattg
    22741 ttggaggagc tttatttatg ggtcttggaa cttatatatt aggtaaagaa aagcttaatt
    22801 aaatttattg tataaattat aactctcttg ataaatacat ttttagtatt gttgagagag
    22861 ttatttttat atttttgaaa aaatatttga aacaaaaaaa atatgggagc atacgaaaat
    22921 atatcggtta tatatataaa aaatacgttt atatatgaat tatatagttc taaatataaa
    22981 aaaagttaaa gtcctaccgt aaaaaagcgc attttgaata agataacaaa tatgataaaa
    23041 ttggtcttgt tgaaattttt aggggggata tgatgacaaa gaaactagta atatcaaaaa
    23101 caa
//
LOCUS       DAEPKC010000062        23023 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.062, whole genome shotgun sequence.
ACCESSION   DAEPKC010000062 DAEPKC010000000
VERSION     DAEPKC010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 23023)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23023)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23023
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.062"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            148..3694
                     /locus_tag="KR294_002414"
                     /pseudo
     CDS             148..3694
                     /locus_tag="KR294_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453516.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
     gene            3879..5813
                     /locus_tag="KR294_002415"
     CDS             3879..5813
                     /locus_tag="KR294_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgiQ family radical SAM protein"
                     /protein_id="HBH0240485.1"
                     /translation="MENKFLPISKQDMIDRGWEELDFVLVTGDAYVDHHSFGTAIISR
                     VLESAGYKVGIIAQPDWRTTDDFMKLGKPRLAFLVNAGNMDSMVNHYSVSKKHREKDM
                     YSPGGKMGYRPDRATIVYCNKIREAYSDVAIVIGGIEASLRRFAHYDYWSDKVRKSML
                     IDSGADLLVYGMSEKQIVEVANALNDGYDPKYIRHIDGTCYISDTLEEIYDKYILIPS
                     YKEICEDKMKYVEAFKIQYDEQDPFRGNIIVQPHGSKYLVQNKPEKPLSREELDEVYG
                     LPYQKTYHPVYEKFGGIPAIEEVKFSIVSSRGCFGSCSFCAITFHQGRAVQSRSEKSI
                     IDEAIGITNLDDFKGYIHDVGGPTANFRRPACKKQITKGACKNRQCLSPSPCKNLDAD
                     HSEYLHLLRAVRKLPKIKKVFVRSGIRYDYVMADKNNKFLRELIEHHVSGQLKVAPEH
                     ISEEVLKYMQKPAGKTYDKFRQKFFAINEELGKKQYLIPYLMSSHPGSTLNSAIELAE
                     YLRDTHYQPEQVQDFYPTPGTLSTTMFYTGIDPLTMKPVYVPKSKRDKAMQRALLQYR
                     APRNYDLVYSALVEAGREDLIGFGHRCLIKPKNEKPYFNRNNSKKNVSKGTNKNKKTN
                     TNNRSNKNQQKSSTKKKKKH"
     gene            5919..6914
                     /locus_tag="KR294_002416"
     CDS             5919..6914
                     /locus_tag="KR294_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBH0240486.1"
                     /translation="MKKYISIILLVVLTMVVLVGCSPGKDNPKNKELSVVKQVKVAVP
                     DGLPAVAIAKLANENPEIKEGYETVYSIEKTPEAISTRVMKKDADIAIVPSNMAAIAY
                     NKTSSYNIVGTVGMGSLYLVSTENIKDYSDLVGKEVGCTGKGLTPDITIKSLLLQKDI
                     NYSDIKFNYVNSASELVPLLATGKVKTGIVPEPALSALMSKNPDIKIIKSLNDSWKEV
                     SGSKDGYPQSTLIVKSEFLRDNKDFVDSFVGQLSNSIDWANKNPEELGAYSEKIKIST
                     ESKIIGKSLERANLKYIPVKDMIKDYKNYYEKLANFDDKTLGGKVPDEAIYFVEK"
     gene            6886..7671
                     /locus_tag="KR294_002417"
     CDS             6886..7671
                     /locus_tag="KR294_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBH0240487.1"
                     /translation="MKQYTLLRNKKNKEQFIDKMEVTLSCVILLFLWQIIALKIDNDI
                     FLPTVGQVFNSIKEIMLNSSFYIDILYSMGRCFFSFLLAMIFAIILSIVSYLNRFFRN
                     LLKPINALTRSIPTMILVVLALIWFEKDSTPFIVGFTIVFPILYDNVLGAILNIDKNL
                     LEMANVYKIRFIDKVLKIYLPAIKFQIISILVSTFSLSLKVAIAGEVYSQPTYGIGTM
                     IQTEKINFNTSGIFAWIIIVLLISAILQIAQKFLARRAFLWKR"
     gene            7659..8357
                     /locus_tag="KR294_002418"
     CDS             7659..8357
                     /locus_tag="KR294_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0240488.1"
                     /translation="MEKIKLSIENINKRYDSRIIFRDFNIDFYVNEVNCILGKSGCGK
                     TTLLNIISGIIKNDTNNLNIKENLNRVGNKLEASYIFQDDRLIDWLTVEENIKIVVNK
                     YYNKTQLNKICDEYLELVGISDYKKFYPQMLSGGIRQRVNIARAFIYPSKNIIMDEPF
                     KSIDAKNTQLIMDNFRNILRKEKRTVLFVTHNIEEALFLADRIFILGDSPIRIKKILK
                     NSKELEKNEVLKLI"
     gene            8480..8953
                     /gene="ybaK"
                     /locus_tag="KR294_002419"
     CDS             8480..8953
                     /gene="ybaK"
                     /locus_tag="KR294_002419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HBH0240489.1"
                     /translation="MVKTNAMRILDSNKIDYKVMSYEVKSEHVDGVEVAHDIGRDVNE
                     VYKTLVTQGVSKNIYVYVIPVHENLDLKKAAKVAKEKSVEMIHVKDINKLTGYIRGGC
                     SPIGMKKLYKTFVNESAKNLDTIIVSAGKIGYQIELSPFDLQRLIKVEFVDVIKK"
     gene            9150..9989
                     /locus_tag="KR294_002420"
     CDS             9150..9989
                     /locus_tag="KR294_002420"
                     /EC_number="4.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate hydratase"
                     /protein_id="HBH0240490.1"
                     /translation="MRKIKSEQIVEQVKKLCIEASLYLGEDVLSCIKEKAKSEKSEVG
                     KNILNILVENAEIAKEKNIPICQDTGMAVFFVEIGQEVLIEGDTLTDAINEGVRQGYE
                     EGYLRKSVVSPINRVNTKDNTPAVIHYDMVKGDKIKIEFAAKGFGSENMSKMKMLKPS
                     DGLEGIKKFIIDTVSEAGPNPCPPMVIGVGIGGTVDKCAQIAKKALFRELGEFNKDEN
                     IAKLESELLTAINKLGIGPQGLGGTTTALGLNIETFPTHIAGLPVVVNINCHASRHKK
                     VVI"
     gene            10002..10550
                     /locus_tag="KR294_002421"
     CDS             10002..10550
                     /locus_tag="KR294_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S-containing hydro-lyase"
                     /protein_id="HBH0240491.1"
                     /translation="MIKITTPVNEIDIAKLNCGDTISLSGILYTARDAAHKRLIDCIN
                     KGEELPFDVYGQGIYYVGPTPTKPGEVIGAAGPTTSYRMDDLTIPLLERGLRLMIGKG
                     KRSDEVIEGMQKYGAVYLAAIGGAGAYISNSIKSCEIIAYEDLGAEAIRKIVVEDLKL
                     TVAIDSYGNNIYEQGRAIYECK"
     gene            10616..11797
                     /locus_tag="KR294_002422"
     CDS             10616..11797
                     /locus_tag="KR294_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent malic enzyme"
                     /protein_id="HBH0240492.1"
                     /translation="MSKDYAKLALEMHEINKGKVSVESKVEVKTKDDLSTAYTPGVAE
                     PCLKIHENQDDVYRYTSKGNLVAVVSDGSAVLGLGNIGAEASIPVMEGKAILFKQFAD
                     VDAFPICLKTNDVDEIVKSVELMEPVFGGINLEDISSPRCFEIEERLKKSLSIPVFHD
                     DQHGTAIIVAAAIINSIKLIENKKIEDLEIVINGAGAAGIAIAKILLNMNVKNIILCD
                     RSGALEASIENLNYVQKEMLKVTNIRNEKGPLKDIIKGKDVFIGVSGPGAVTKEMVES
                     MSEKPIILAMANPAPEIMPEEAKLGGAFIMGTGRSDFPNQVNNVLAFPGIFRGALDVK
                     AKEINEEMKIAAAYAIANTISDEEICPEYILPDVFNKNVVKNVAKAVKEAAIKTKVNR
                     I"
     gene            11965..12351
                     /locus_tag="KR294_002423"
     CDS             11965..12351
                     /locus_tag="KR294_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009248914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH0240493.1"
                     /translation="MEYKVNDQELNASMFIPFVNRIWPGDYDTDKTQTALSKTLNITA
                     YDDKVLVGCLRVLSDGYYFGTITELLVLPEYQKQGIGSKLFQLAKENTPTMLYFGAQP
                     GVEEFYEKNGCQRSLQSYIIKKKDSY"
     gene            12501..12764
                     /locus_tag="KR294_002424"
     CDS             12501..12764
                     /locus_tag="KR294_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HBH0240494.1"
                     /translation="MEETKFCQCCAMPMGQTDELYGTNKDGSKSTDYCSYCFKDGEFT
                     ADISMEEMIEVCIPHMLQSNKDMTEDEARTMMNNFFPTLKRWK"
     gene            13290..13973
                     /locus_tag="KR294_002425"
     CDS             13290..13973
                     /locus_tag="KR294_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0240495.1"
                     /translation="MSSILLVEDDLSLIYGLEFSIQKSGFSIDIARTVKEAMQMYEEK
                     NYDLLLLDVSLPDGNGFQICEKVREVSNIPIIFLTASDEEVNVVMGLDMGGDDYITKP
                     FKLNELISRIKALLRRYNVASNVNELSSNNITIKLLENRVFKGKFEVELTTAEYKLLC
                     LFMKNKNIVLTRKNILDKLWDGNGSFIDDNTLSVYVRRLRNKIEDNPENPKFLLTVRR
                     MGYKWNVIK"
     gene            13984..15225
                     /locus_tag="KR294_002426"
     CDS             13984..15225
                     /locus_tag="KR294_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH0240496.1"
                     /translation="MKIFSNKDIKIFFLMLISILVMFIIVGQIVVISITNNYKKTLIE
                     HDYNIAGYLYSIGVDKSKIPSAFVAHEDKYILKGKEILDTAGYGFDIDVSFTPSVKLF
                     QSKYIKTMSIYLLVFFTMIIFILYMYFFRQQSKIEEASYKIDLFMNGNINERLNTYEE
                     GSLSKLFSSIDVMSTSLNTHILKEKQSREFLKNTISDISHQLKTPLTALIMYNQILQE
                     ESHNSDVVEAFVQKSQSELERIETLIKNLLKITKIDSKTIILNKNNVNLKNLIVKILY
                     SFETRAEKEGKVISVNGSENTLLFCDYEWMSEALSNLIKNALDNTKENDKITIEWFET
                     TITTIVSVKDTGNGIHVEDIHHIFKRFYRSKFSKDNQGLGLGLPLVKSIVEQHNGTIS
                     VESKLSQGSIFTISFLKLTNM"
     gene            15297..15980
                     /locus_tag="KR294_002427"
     CDS             15297..15980
                     /locus_tag="KR294_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002574824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0240497.1"
                     /translation="MDILVVNNLCKTYGNGYTKVEALKDVSFTVSKGEFVTVVGESGS
                     GKSTLLNLLGGLDTPTSGRIFIDGKEICSMKEEKQTIFRRRNIGFIFQAYNLIPELTV
                     EQNIIFPLLLDYKKPDTIYLDEVLTILGLKDRKNHLPNQLSGGQQQRVAIGRALITKP
                     SIILADEPTGNLDSKNSNDVISLLKVTAEKYNQTIIMITHNTNIASTADRILQVSDGV
                     LTDLGVNRE"
     gene            15977..18307
                     /locus_tag="KR294_002428"
     CDS             15977..18307
                     /locus_tag="KR294_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0240498.1"
                     /translation="MRSYLELVPQYAKVHKKKNRTTILCIIIAVCLVTAIFGLADMAI
                     QCQKIQFIKDDGNWHIVIRNIDEKFISEINSRVDIAHHGRGQVVDNGEFKSKEILIQG
                     LDEEVAKQFNLEIIRGRYPIGENETLIDEDAVKSFNLKIGDFIKIKLADGRNKNYKIV
                     GEYSSISSLRATDKHGLILSILGTQAIKKSETYDYYYITFKEKVNIRKATSDIKNTFN
                     LSDKQIGKNERLLSIIGQGDSDFSKPLYLTAGLLFVLVLVASIIMIYNSFNMSVIERV
                     KFFGLLRCLGSSKHQVKKFVVLESLILSIKAIPIGLVLGSLVTIISSIFLKYVNELFS
                     SMPILKVSFIGIAFGIIVGFLTVILSAIIPAKKASRVSPLSAVRGNLMSKEILNNGKT
                     SKVANIGSFKIETSMGLNHAFSRKKSFVLMTSSFAISIILFLGFSVLIDLMYQGLKPM
                     KPEAPHISIVDPNFKSVLTKEDINEISNIKGVKKVYSRMMTDIEATYNGKKTKSQLIS
                     YEKYQFNWAKKYLLKGEVNENKLQSENLALVEEGHGFDIGDKIYIKNGNAEKELEVGG
                     ILSSIPFEAKDKYIGNIITSENTFTNITGIKGYIIMDIQVDKDTPGDLIENIRRVVDD
                     NLEVRDKRQSNLEVKNSFYTMATFVYGFVFIIAIISMFNIINSMNISVTSRKNYYGVM
                     RAVGISNRQLRRMVIVEAGSYAVSGCLLGSILGLILHRYMFISLVSSMFHLEWQVPFN
                     LLLITVLTMIIITLLSVRKPIKKICELDIIDSINAQ"
     gene            complement(18488..19330)
                     /locus_tag="KR294_002429"
     CDS             complement(18488..19330)
                     /locus_tag="KR294_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBH0240499.1"
                     /translation="MINIGDFNKLTVKRKTEFGYFLDGQTNNTKDDILLHNRLIGKNE
                     INIGDEVNAFIFKDSDDRTAATLIPPLAKVGDVAHLKVVDNTDIGTFIDMGLPKDILV
                     PFKAKTYPLFRDEKYLFYIYLDKSKRIAATTDIDSYLLTDHTYNVGDIVTGVVYGFQT
                     NNSAMICVDNKYAGVILHNEYFTELKTGDVLENLHVIKIYEDGKLGLSPRGNRKDELD
                     TLENKILSYLEGSDGYMRFNDKSDPKDISILFNSSKKNFKRALGVLMKKGLIYQDEEG
                     TYLK"
     gene            19625..20359
                     /locus_tag="KR294_002430"
     CDS             19625..20359
                     /locus_tag="KR294_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH0240500.1"
                     /translation="MKIVNKSSNIPLHTQLSSIIREMIETGELKEGDAIMPERELCNI
                     QNVSRMTVNKTIVGLVTEGLLYRVQGKGTFVAKQKKKYQFSNVKGFTDVMKEKGVNIK
                     TDILSFEMELPDDLVKRKLGISDNTTNIYKIVRLRYTDGEPFGLEIVYLSEEMCKGLT
                     KGILDNSSLYRVLNEKYGYKIQKAEQVMEPVILSDEESKLLETDEGALALKLHRNSYN
                     REGRPIEYTISIFRTDKYQYEIVLSE"
     gene            20369..21502
                     /gene="nagA"
                     /locus_tag="KR294_002431"
     CDS             20369..21502
                     /gene="nagA"
                     /locus_tag="KR294_002431"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HBH0240501.1"
                     /translation="MKCLINGKIILKNQILENKVLVFDEKIIDIADSVPKDCEVIDAD
                     GKYISPGLIDIHIHGNMGKDTMDSTDESIETISKSIMRHGVTSFLPTTMTMDKEHVYD
                     ALEVIKKAQNRKLEGAQVLGAHLEGPFINENYKGAQNEKFIINSKYEFIKEYKDVIKV
                     ITYAPEKDIDFDFTREIKRCTDIVLSIGHSNANYDQAKEAINLGVTNVTHMFNAMTGL
                     NHRDPGVVGAALTTNVYSELIADTIHINKDLFQFILNNKGKERLILITDSIEAGGLED
                     GNYSLGGQKVIVKGNEARLENGALAGSVLSLNKMVFNFLNNTNLKVNEAINLASLNPA
                     TSLGINDKKGSLEIGKDADIAVFDENLDCKMTLCLGEVVYKNI"
     gene            21601..22350
                     /gene="nagB"
                     /locus_tag="KR294_002432"
     CDS             21601..22350
                     /gene="nagB"
                     /locus_tag="KR294_002432"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012425552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HBH0240502.1"
                     /translation="MRVLVCKDYDGMSKKAAEMIAAQIVLKPNSILGLATGSTPVGMY
                     RDLVKKYNDNIVDFSDVMSFNLDEYYKLPISNDQSYDYFMKENLFNHVNIKPENTHLP
                     NGMADDIEKECMNYEASIDAAGGIDVQVLGIGRNAHIGFNEPDTKFAKRTHVVELTES
                     TIEANARFFKSREDVPKKAVSMGIGSILKSKKILLLASGEEKADAVYNTVYGDITPEV
                     PGSILQLHKDTIVIVDEAAASKLNPKDYKLV"
     gene            22502..22774
                     /locus_tag="KR294_002433"
     CDS             22502..22774
                     /locus_tag="KR294_002433"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240503.1"
                     /translation="MLKIIMFSGILSSIIKLPIIGILPTGNIKKNTGISDSKKDGKQR
                     RSNLGISIYQLPSFLYSLINNSVPSNKPIPPEEIKLIKMYLLKSCI"
BASE COUNT         9172 a         2426 c         4035 g         7390 t
ORIGIN      
        1 ataaatctta agctatctta tttaattcta atacaggaag aaggtaaatg tatattgaaa
       61 aaatcataga aatagaagta aacaatttaa ataaatacaa aggtttgcaa aagaagtaat
      121 ataattatat acaatgagga tgtgagtatg atgaacagac taaagccaag aattttaggt
      181 attagtatct tgtttattat tataattatt ttaacatgtg gagctgtttt caagtttaaa
      241 tttaaattag ataataaatt aaaagaaacc acacatacat atttgtctga gtttacagaa
      301 cacaatataa ttaatctcaa gacaagactt agtggtcaat ttgacatgct tgaatctatt
      361 gctaacttca taggaaactt gaataatata aatgatgaaa tggtgattga tttaatggat
      421 tctgatgtaa agcgaagttc tttaattaga atgactatct ctacattaga tggggaatgt
      481 tattctaatg atggaattac ccataatgtt caagatagag attattttaa aaaagctaaa
      541 aatggagaaa agaatatatc agagccttta aaatctattg ttaataataa agaaataata
      601 gttttatcta ccccagttta taaaagtggg aaaatagttg gtgttttaag tggaatttat
      661 gattcaaaaa agttaaatga attattagga ttatctgcat ttgatgaaaa agcagatgtt
      721 tttgttgcaa agaaaaatgg agatataatt gctcaaaaaa caaataaaaa tagtaagacg
      781 atatcatgta tatttcagct ttttgacaaa gataattgtg atgaagttga ttgtctaaaa
      841 actataaaag aaaatatgaa aaatgataag tctgagtatt ttaattataa cttagataat
      901 gaaaaattta tgttaaacta tcagccactt ggagttaatg attggtatgt tttttctgtt
      961 gtgccaaata aaatagtgtc tattcagtca gagaatatat cttatgatgt atatattttt
     1021 gcatgaaata ctactagtta tattaatttt tataatatat atagcatgta ttataaataa
     1081 taacaccaaa attattataa atgaaaaaga aaaatttaaa gtactcactg ataatatact
     1141 aggaggggtt aaaacctgtt taaaagatga atatatgact atgacatatg taagtcaggg
     1201 gtttttagag cttacaggtt actcttgtga agatttaaat aaaatattta aaaatagatt
     1261 taaagacatg atttataaag atgatttaga caagtttaat tgtattattc taaaccaatt
     1321 agaaaaacaa gataaaattg aagttgaata tagaattgta agaaaagatg gaagtataat
     1381 ttggattttg gagagaagta agtctataaa tgataataaa ggaagtgagt gtattcaggg
     1441 agttttaact gatataacag aatttaagaa aatacaagaa gagttagatt caaaaagatt
     1501 tgaaatacag gctatcaatg atagtattgt tggtggaata gtgataactg agataaatga
     1561 tgattttgat agtatatatt taaatgaagg ttatttaaat atgattggat atacacgcaa
     1621 acaactgaaa gatgagctaa ataataaatt aatcaaactt atttttaaag atgatagaac
     1681 agaattaatt aatagtataa acaaacaact caaattaagt gatacatttg catctgaaca
     1741 aagagttgaa aaaagggatg gcactattat atggatttta ttaaaaggaa gaaagatgat
     1801 ttatgataat ggaaaatctg tactttgttg tgttattgta gatattactt ctgctaaatt
     1861 attagagcaa gaacttaaaa agagtgaaga acgtcatgaa atcattctaa agcagacgca
     1921 aaatattata atagaatggg atatagaaaa agataaaatg aatatatcac ctaattggta
     1981 taataagttt aaatatgacc ctataactga aaacgcaaca aaaaatataa ttaaatcagt
     2041 agatatatat catgatgata tggataagtt tatttcatta attaaactta cttcacaagg
     2101 tagtgagtat gaagagtgtg aaattagact tagaactaga gatactattt acgcttggtt
     2161 tagtataaag gcaacaactt tatttgataa taatggtaaa ccttataaag tagtaggaag
     2221 tttgactgat attgatgaat caaaacgaga agctgaaaag ttgaaagaaa gggcagaaaa
     2281 agaccctctt acagatttgt ataataaaaa agcatcacaa tcacttatag aagagtacat
     2341 aacattggat aaaaaaagaa aaggtgcttt aatgattatt gatattgatg actttaaagg
     2401 aataaatgat aatttaggac atttatatgg ggatgctgta ttaagtgaag ttgcaaatga
     2461 cctaataaat ctatttagag caaccgatat agtaggcaga attggtggag atgagtttat
     2521 tgtatttata aaagatattt ctaaaacaag agatattata aataaagcag aagaattggt
     2581 aaaaacattt gaaaggtctt ttttaggtaa aggacgaaat tataaaatat cattaagtgt
     2641 aggaattgct aagtttccac aagatggtat ggactatatg acactattta gaaatgcgga
     2701 tatagctctt tactcagcca aagggaaggg caagaattgt tatacattgt atgataaaaa
     2761 aattgataaa gtccaatata taactaatac aagaaatgca ggagatagtg ataatgtaga
     2821 gatgtctttt aaagaacata tcacaaatta tatatttgat atactatatg aatcaagtga
     2881 tatagaagtg gcagtaaatt taattctaag tattgtaggt aaacacttta atgtgagtcg
     2941 catgtatata tttgaaaatt cagatgataa tcgagtatgt aaaaatacat ttgaatggtg
     3001 taacgaaggt ataacctcgg aaattaataa tcttaaaaat atttgttaca aggatttagg
     3061 caactatctt ttaaatttta atgcagatgg gttattttat tgtaatgata ttgaaaattt
     3121 aggtagtgat gtgaaaaaag tacttaagcc acaaggcata cgttcaatat tacaatgtaa
     3181 aattttagag ggtaatgaat ttagagggtt cataggattt gatgaatgtt catataatcg
     3241 tatgtggact aatgatgaag tgaacacttt gacatttata tctaaaacgc tcaatatgtt
     3301 tttattaaaa atgcgtattc agagtaagct agaagagtct ttaacaattc aaaaatctgt
     3361 gatggataat atggatatat gggcatatgt tgttgacagg aatacctatg aattactatt
     3421 tatcaataaa aaaatgcttg agtcagcacc aaacactcat gtaggtgatt tatgttataa
     3481 agcgatatgg aataatcaag ataaaccttg taaaaaatgc cctatgatat atttaaaaga
     3541 tggtgatgat acttataaat cattcatgca taataaaaag tttgaggtac aggcaaatat
     3601 aactacaact actttgaaat ggtttgatgg taaagatgca tgtttaatat ttggaagtga
     3661 aataactagt attgaagctg aagaaaatac ttaaaatact gtgttatata tatacttaaa
     3721 atcgcaattt gaatttatta gacttaaaat gtctatataa atcatttaag ttgtggtttt
     3781 aagtattttt tatgatataa ttaagcgtta agaacaaaat taaaagatac ttttgtataa
     3841 aaaaatattt gttaaatata tattgagcag gtgataatat ggaaaataag tttttaccaa
     3901 taagcaaaca agatatgata gatagaggat gggaagaatt agattttgtt ctagttacag
     3961 gagatgctta tgtggaccat catagttttg gaacagcaat aatatctaga gttttagaaa
     4021 gtgctgggta taaagttgga ataatagctc aaccagactg gagaactaca gatgatttta
     4081 tgaagctagg aaaacctaga cttgcatttc tagttaatgc aggaaatatg gattcaatgg
     4141 tcaatcatta ttctgtaagt aaaaagcata gagaaaagga tatgtattct ccaggtggga
     4201 aaatgggtta tagaccagat agagctacta tagtatattg caataaaata agagaagcat
     4261 acagtgatgt tgcaatagta ataggtggaa ttgaagcgag cttaagaaga tttgcacact
     4321 atgattattg gagtgataag gttagaaagt ctatgttaat agatagtgga gcagatttat
     4381 tagtttatgg tatgagtgaa aagcagattg tagaagtagc caatgcactt aatgatggat
     4441 atgacccaaa atacattaga catattgatg ggacatgcta tatttcagat acattggaag
     4501 aaatatatga taaatatata ttaattccat catataaaga aatttgtgaa gataaaatga
     4561 agtatgtaga agcttttaaa attcaatatg atgagcaaga cccatttaga ggtaatataa
     4621 ttgttcaacc tcatggaagt aagtatctgg ttcaaaataa gccagaaaaa ccacttagta
     4681 gagaagaact agatgaagta tatggattac catatcagaa gacataccat cctgtgtatg
     4741 aaaaatttgg aggaatacca gctatagaag aagtaaaatt tagtatagta agttcaagag
     4801 gctgttttgg tagttgttca ttttgtgcaa taacatttca tcaaggtaga gcagtgcaaa
     4861 gtagaagtga aaaatcaatt attgatgaag caataggaat aacaaattta gatgatttta
     4921 aagggtatat acatgatgtt ggaggtccaa cagctaattt tagaagacca gcatgtaaaa
     4981 aacaaattac taaaggtgct tgtaaaaata gacaatgctt atctccatca ccatgtaaaa
     5041 atttagatgc agaccacagt gaatacttac atttacttag agctgtaaga aaattaccta
     5101 aaataaaaaa ggtgtttgtg cgttctggaa ttagatacga ttatgtaatg gcagataaga
     5161 acaataaatt tcttagagag ttgatagagc atcatgtaag tggtcagtta aaggtagccc
     5221 cagaacatat atcagaagaa gttttaaagt atatgcaaaa accagcagga aaaacttatg
     5281 ataaatttag acagaaattt tttgctataa atgaagaatt aggtaaaaag cagtatttga
     5341 taccctattt aatgtctagt caccctggtt ctaccttaaa tagcgctata gagttagcag
     5401 agtatttaag agatactcac taccaaccag agcaggttca ggatttttat ccaactccag
     5461 ggactctatc tacaaccatg ttttatacag gtattgaccc gcttacaatg aagccagttt
     5521 atgttcctaa atcaaaacgt gacaaggcaa tgcaaagggc tttattacaa tatagagcac
     5581 ctagaaatta tgatttggta tactctgcgt tagttgaagc aggaagagaa gacttaattg
     5641 gttttggaca tagatgtctt ataaagccaa aaaatgaaaa gccttatttt aatagaaata
     5701 attctaaaaa aaatgtatct aaaggaacaa ataaaaacaa aaaaactaat acaaataaca
     5761 gaagtaataa aaatcaacaa aaaagttcaa ctaaaaaaaa gaaaaaacat taaagtataa
     5821 ataaaaatac ttaaaaaaga aggattattc gataaattaa cagaaattag tataaataaa
     5881 tataattatt ttaatgacgt tacctttggg aggaagagat gaaaaagtat atttctataa
     5941 tattattagt ggtgttgact atggttgttt tggtaggatg ttcaccagga aaagataacc
     6001 ctaaaaataa ggagctatca gttgtcaaac aagtaaaagt agctgttcca gatggactac
     6061 cagcagtggc aatagctaaa cttgcaaatg aaaatccaga gattaaagaa ggatatgaaa
     6121 cagtgtatag cattgaaaag acacctgaag cgatttccac tagagtgatg aaaaaagatg
     6181 cagatatagc tatagttcct tcaaacatgg ctgcaatagc gtataataaa acttcatcat
     6241 ataatattgt tggaactgta ggaatgggtt cactttattt ggtgtcaaca gaaaatataa
     6301 aagattactc tgatttagtt ggtaaagaag ttggatgtac tggaaaagga cttactccag
     6361 acataactat aaaaagtctt ttgttacaaa aggatataaa ttattcagat ataaaattta
     6421 attatgtaaa ttcagcaagt gaactggtac cattattggc tactggtaaa gttaaaacag
     6481 gtattgttcc agaacctgca cttagtgctt tgatgtctaa aaatccagac ataaaaatta
     6541 taaaaagttt aaatgactca tggaaggaag taagtggttc aaaagatggt tatcctcaat
     6601 ctactttaat tgtaaagtct gaatttttaa gagataataa agattttgtt gattcttttg
     6661 taggtcaatt atcaaatagt atagattggg caaacaaaaa tcctgaagaa ttaggtgcat
     6721 attctgaaaa aataaaaata tctactgaat caaagataat aggaaaatct cttgaaagag
     6781 ctaatttgaa atatattcca gttaaggaca tgattaaaga ttataaaaat tactatgaga
     6841 aattagctaa ttttgatgat aagacattag gaggcaaagt accagatgaa gcaatatact
     6901 ttgttgagaa ataaaaaaaa taaagaacaa tttatagata aaatggaggt aacactttct
     6961 tgtgttatcc tcttattttt atggcaaatt attgctttaa aaattgataa tgatattttt
     7021 ttaccaacag taggtcaagt gtttaatagt ataaaagaga ttatgctaaa ttctagtttc
     7081 tatatagata tactttactc tatggggaga tgttttttta gttttttact ggctatgatt
     7141 tttgctatta tactttcaat agtgtcttat ttaaatagat tttttagaaa cttattaaag
     7201 ccaatcaatg ctttgacacg ttcaatacca actatgatat tggtagtact tgcacttatt
     7261 tggtttgaaa aggatagtac cccttttata gttggattta ctatagtttt tcctatattg
     7321 tatgataacg ttttgggcgc tatattgaat atagacaaga acttattaga aatggctaat
     7381 gtgtataaaa taaggtttat agataaggtg ttaaaaattt atttaccagc cataaaattt
     7441 caaattatat ctatactagt atcaacattc tctttaagtt tgaaagttgc tatagcagga
     7501 gaggtatata gtcaacctac atatggtatt ggaactatga tacagactga aaaaattaac
     7561 tttaacacat ctggaatatt tgcatggata attattgttc ttttaatatc tgctatttta
     7621 caaatagctc aaaagttttt agcaaggaga gcttttttat ggaaaagata aagttgagta
     7681 ttgaaaatat aaataaaaga tatgatagtc gtattatatt tagagatttt aatattgatt
     7741 tttatgtaaa tgaggtaaat tgtatccttg gaaaatctgg ttgtggaaaa actacactct
     7801 tgaacataat aagtgggatt attaaaaatg acaccaacaa tctaaatatc aaagaaaatt
     7861 taaatagagt aggaaataag cttgaagcta gttacatatt tcaagatgat agacttatag
     7921 actggttaac agtagaagaa aatataaaga tagttgtaaa taaatactat aataaaactc
     7981 aattaaataa aatttgtgat gaatacttgg aattggttgg aattagtgat tataaaaaat
     8041 tctatcctca aatgcttagt ggaggtatta gacaaagagt aaatattgct agagctttta
     8101 tatatccatc aaaaaacatt ataatggatg aaccttttaa atctattgat gcaaagaata
     8161 cacagcttat aatggataat ttcagaaata tattaagaaa agaaaagaga actgtgttat
     8221 ttgtaactca taatattgag gaagcattgt ttttagcaga taggatattt attttaggag
     8281 actctccaat tagaataaaa aaaatattaa aaaattctaa ggaattggaa aaaaatgaag
     8341 ttttgaagtt gatatagagt tataataata ctgtcgtttt aaaatatatt tggttaaaat
     8401 ctataagact atattaaaat agtacagaat attcaaaact gtgtataatg ttcgtatttt
     8461 ataaaaagga agtgaatgta tggttaagac taatgctatg agaatattag attcaaataa
     8521 gattgattat aaagtaatgt cttatgaagt gaaaagtgaa catgtggatg gtgttgaggt
     8581 ggcacatgat ataggaagag atgtaaatga agtgtataag acattagtaa ctcaaggagt
     8641 tagtaagaat atatatgtat atgtaatacc agtacatgaa aacttagact taaaaaaggc
     8701 tgcaaaagta gctaaagaga aaagtgtaga gatgattcat gtaaaagata taaataagct
     8761 tacaggttat attagaggcg gatgttctcc tataggtatg aaaaagcttt ataaaacttt
     8821 tgtaaatgaa agtgcaaaga atttagatac aattattgtg agtgcaggaa aaataggata
     8881 tcaaatagaa ctatctccat ttgatttaca aagacttata aaagtagaat ttgtagatgt
     8941 aataaaaaaa taagaattac atataaaata tagagcttat attctcaata ataggtgttg
     9001 taatattaat aaaatgaata ataattttaa aataaatatt cagttactta tgtgtaattg
     9061 gtataaaaat attgagaaat tttaaaaaca atggtaaagt gtaagtataa tcacgaatat
     9121 tttttataaa gtaatggagg gatgttcgct tgagaaaaat aaaatctgaa caaatcgtcg
     9181 agcaggtaaa aaaactttgt atagaagcga gcctatattt aggagaagat gttttaagtt
     9241 gtataaaaga aaaagcgaaa agcgaaaaga gtgaagttgg aaaaaatata ttgaatatat
     9301 tagttgaaaa tgctgaaata gctaaagaaa aaaatatacc aatatgccaa gatactggta
     9361 tggctgtatt ttttgttgaa ataggacaag aagttttaat tgaaggagac acacttactg
     9421 atgctataaa tgagggagta agacaagggt atgaagaagg ctacttaaga aaatctgttg
     9481 taagtccaat taacagagta aatacaaaag ataatacacc tgctgttatt cattatgata
     9541 tggtaaaagg tgataaaatt aaaatagaat ttgcagctaa gggatttgga agcgaaaata
     9601 tgagtaagat gaaaatgtta aagccatcag atggattgga aggaattaaa aaattcataa
     9661 tagatacagt ttcagaagct ggacctaacc catgccctcc tatggtaatt ggagttggta
     9721 taggtgggac tgtggacaaa tgtgctcaaa tagctaaaaa ggcacttttt agagaactag
     9781 gtgaatttaa taaggacgaa aatatagcaa aacttgaaag tgaactatta acagctatta
     9841 ataaacttgg tataggacct caaggcttag gtggtactac aacagctttg ggattaaaca
     9901 tagagacttt tcctacacac atagcaggtc tacctgttgt tgtaaatata aactgccatg
     9961 catcaagaca taagaaggta gtaatttagg aggaaaataa aatgataaaa ataactacac
    10021 ctgtaaatga aattgatata gcaaaattaa attgtggaga tacaattagt ttgagtggta
    10081 tactttatac agcaagagat gctgctcata aaagattgat agattgtata aataaaggtg
    10141 aagaattacc atttgacgta tatggtcaag gaatatatta tgtaggacct actcctacaa
    10201 agccaggaga agttataggt gctgcaggtc caacgacgag ttatagaatg gatgatttga
    10261 ctatacctct tttagaaaga ggtcttagat tgatgatagg caagggaaaa agaagtgatg
    10321 aagttataga aggtatgcaa aaatacggag cagtttatct tgctgcaata ggaggagctg
    10381 gagcgtatat ttcaaattca ataaaatcat gtgaaattat tgcatatgaa gatttaggag
    10441 ctgaagctat aagaaagatt gtagtagaag accttaagct tacagtagca atagatagct
    10501 atgggaataa tatatatgag caaggtcgag caatttatga atgtaaataa tgtttagaaa
    10561 taaatatgaa tatcaaaatt aaaaatagtt gtgtatattt taaggaggaa aattgatgtc
    10621 taaggattat gcaaaattgg cattagaaat gcatgaaatc aacaaaggga aagtaagtgt
    10681 agaaagcaag gtagaagtta aaactaagga tgatttatca acagcatata caccaggggt
    10741 tgcagaacct tgtttaaaaa tacatgaaaa tcaagatgat gtttatagat acacttctaa
    10801 agggaatcta gtagcagtag ttagtgatgg aagtgctgta cttggattag gtaacattgg
    10861 tgctgaagca tctatacctg ttatggaagg taaagctata ttgtttaaac aatttgcaga
    10921 tgtagacgct tttccaatat gtttaaagac taatgatgta gatgagatag ttaaatctgt
    10981 agagttgatg gaacctgtat ttggaggtat aaatttggaa gacatatctt ctccaagatg
    11041 ttttgagata gaagagagat taaaaaaatc tttaagtata cctgtttttc atgatgacca
    11101 acatgggaca gcaataatag ttgcagcagc cataataaac tcaataaagt taattgaaaa
    11161 taaaaaaata gaagatttag aaatagttat aaacggagca ggagctgctg gtatagccat
    11221 agcaaagata ctacttaata tgaatgttaa aaatataatc ttatgtgata gaagtggagc
    11281 attggaagct agtatagaaa atctaaacta tgttcaaaaa gaaatgttaa aagtaacaaa
    11341 tataagaaat gaaaaaggac ctttaaaaga tattataaaa ggaaaagatg tatttattgg
    11401 tgtttcaggt ccaggagctg ttacaaagga aatggttgaa agtatgtctg agaagccaat
    11461 aatattggca atggcaaatc ctgctccaga gataatgcca gaagaagcaa aattaggtgg
    11521 agcatttata atgggaacag gtcgttcaga cttccctaat caagtcaata atgtattggc
    11581 ttttcctgga atatttagag gagcattaga tgttaaggct aaagagataa atgaagaaat
    11641 gaagatagct gctgcatatg caattgctaa tacaataagt gatgaggaaa tatgcccaga
    11701 gtatatatta ccagatgtat ttaataagaa tgtagtaaaa aatgttgcta aggcagttaa
    11761 agaagcagct ataaaaacta aagtaaatag aatataaatt tttatatgct catatattct
    11821 tacttttata tacatatctt tatgattaaa cgtgttagaa aacgtagtaa atttatacta
    11881 tcagacttta cctttattac ttaaaatgat ataatatgaa tattataaat taataaattt
    11941 aaatttattg aggtgcaaga gataatggaa tataaagtta atgaccaaga acttaatgct
    12001 tcaatgttta tcccattcgt taacaggata tggccaggag attatgatac ggataaaaca
    12061 cagactgcat tatcaaaaac tttgaatata actgcttatg atgataaagt gcttgtagga
    12121 tgtctgcgag ttctttcaga tggttattat tttggaacaa ttacagaatt gcttgttctt
    12181 ccagagtatc agaaacaagg cattggtagt aagcttttcc agcttgctaa agagaataca
    12241 ccaactatgc tatattttgg tgcacagcca ggagtagaag agttctatga aaaaaatgga
    12301 tgccaaagaa gtcttcaatc ttacataata aaaaagaaag atagttatta aagttccagc
    12361 tttcaataat cttaaaagta caatatttta gtggaatcat ttcatttttt attactaata
    12421 tgacataaac atgtcatatt agtattgata tacttttaat atggttaaga gccaaagaaa
    12481 aatataagga gtgatttaaa atggaagaaa ctaaattttg ccaatgctgt gcaatgccaa
    12541 tgggacaaac tgatgaatta tatgggacaa ataaagatgg aagtaaaagt actgattatt
    12601 gtagttattg ttttaaagat ggtgagttta cagctgatat aagtatggaa gagatgatag
    12661 aagtttgtat ccctcatatg cttcaaagta ataaggatat gactgaagat gaagcaagaa
    12721 caatgatgaa caatttcttt ccaacattaa aacgctggaa ataattttat gcaaaattag
    12781 ttatatgcaa aacatgaaat atggtgttga gaataagggg tggtgtgctt tatagcatac
    12841 cacctgtttt gttacttgct agttcaggta ttcttgtatg cttaaatatg ttctcatctc
    12901 tctttctatt ttaaattgta aaaatctaaa atatgttatt tatattctac ttctttatcc
    12961 atgtcttttt ctaccacaag tcaaatccaa ctacaaaatc atcattttca attcactgtt
    13021 taatagaatt aacagataaa gagttataaa attttctatt ttttatataa aataatacag
    13081 gtcaagctga cttctagcta cttgggatag tgtatatatt tatgatagtt ataggagtaa
    13141 taccaatcat tagactgttg atttgtgtag tcttttgtaa aaacatttgt tttaatatat
    13201 tgagtttttg aaaaagtaaa attataatta taataaatta agtgtaataa tgtattagaa
    13261 gtaaaaataa ttaaaataga ggtgattaaa tgagtagtat attgttagtt gaagatgatt
    13321 taagcttgat atatggatta gagttctcta tacaaaaaag tggatttagt atagacatag
    13381 caaggacagt aaaagaagct atgcaaatgt atgaggaaaa aaattatgac ttattgcttt
    13441 tagatgtatc cctacctgat ggtaatggat ttcagatttg cgaaaaagta cgagaggttt
    13501 ctaatatacc cattatattt ttgactgctt cagatgaaga ggtaaatgta gtgatgggtc
    13561 ttgatatggg tggagacgat tatataacaa aaccttttaa attaaatgaa ttaatttcaa
    13621 gaataaaagc attacttaga cgttataatg ttgcaagtaa tgtgaatgaa ttaagttcaa
    13681 ataatattac tattaaatta cttgaaaatc gtgtttttaa aggtaaattt gaggtggaac
    13741 ttaccacagc agaatataaa ttattgtgct tatttatgaa aaataaaaat attgtactta
    13801 ctagaaaaaa catattggac aagttatggg atggaaatgg tagctttata gatgacaata
    13861 cattatcagt atatgtaaga cgattgagaa ataaaattga agataatcct gaaaatccta
    13921 agtttctatt gaccgttaga agaatgggtt ataagtggaa tgtaattaag tgagggtatt
    13981 aatatgaaga tattttctaa taaagatata aaaatatttt ttttaatgct tatatctatt
    14041 ttagtaatgt ttattatagt agggcaaata gtggttataa gtataactaa caattataaa
    14101 aaaacgttga tagagcatga ttataatata gctggatact tatatagtat aggtgttgat
    14161 aaatctaaaa taccatcagc atttgttgca catgaagata aatatatttt aaaaggaaaa
    14221 gaaatactag atacagctgg atatggattt gatatagatg ttagctttac accaagtgta
    14281 aaattgtttc aaagtaaata tataaaaact atgtctatct atttattagt attttttact
    14341 atgattattt ttatactata tatgtatttt tttaggcaac aaagtaagat agaagaggct
    14401 agttataaaa ttgatttatt tatgaatgga aatataaatg aaagactaaa tacatatgaa
    14461 gaaggtagct tatcaaaatt atttagttca atagatgtta tgtcgacatc tttaaataca
    14521 catatattaa aagaaaaaca gagcagagaa tttcttaaaa atacaatttc ggatatatcg
    14581 catcaattaa aaactccact tacagcttta ataatgtaca atcagatact acaagaagaa
    14641 agtcataata gtgatgtcgt tgaagctttt gtacaaaaaa gtcaaagtga actagaacgc
    14701 attgaaacat tgattaagaa tttattaaag attacaaaga tagattcaaa aacaataatt
    14761 ctcaataaaa ataacgttaa tcttaaaaat ttaattgtca aaattttgta tagctttgaa
    14821 actagggcag aaaaagaagg aaaggttatt tctgtaaatg gttcagaaaa tacattgttg
    14881 ttctgcgatt atgaatggat gtcagaggct ttaagtaatc ttataaagaa tgcattagat
    14941 aatacaaaag agaatgataa aataacgata gagtggtttg agacgactat aaccaccatt
    15001 gtttcagtta aagatactgg aaatggaatc catgttgagg atattcatca tatatttaaa
    15061 aggttttata gaagtaagtt ttcaaaagat aatcaaggtt taggactggg attaccacta
    15121 gttaaatcta ttgtggaaca acataatggt actatttctg tagaaagtaa actatcacaa
    15181 ggaagtatat tcaccataag ttttttaaag cttactaata tgtaagataa aatacatctt
    15241 gcagtaaggt atatagatta ttattatatt aatcaattag aaaggtgaga gagaaaatgg
    15301 atattcttgt ggttaataat ttatgtaaaa catatggaaa tggatataca aaggtagagg
    15361 cattgaaaga tgtatccttt acagtttcaa aaggagagtt tgtgactgta gttggagaat
    15421 ctggttcagg aaagagtaca ctattaaatc tcttaggagg tcttgatact ccaacatcag
    15481 ggagaatatt tattgatggt aaagaaatat gttcaatgaa agaggaaaaa cagactattt
    15541 ttagacgtcg taacataggg tttatatttc aggcatataa ccttatacca gaactaactg
    15601 tggagcaaaa tataatattc ccattgttat tagattataa aaaaccagat actatttact
    15661 tagatgaagt attgactatt ttaggtctta aagataggaa aaatcatctt ccaaatcaat
    15721 tatctggtgg tcaacaacag agagttgcaa ttggaagggc tttgattaca aagccaagta
    15781 ttatactggc agatgagcca acgggaaatc ttgacagtaa aaatagtaat gatgtaattt
    15841 cacttttaaa agtgactgca gaaaagtata atcaaaccat tattatgata actcataata
    15901 cgaatatagc ttctacagca gatagaatac tacaggtttc tgatggtgtg cttacagacc
    15961 tgggggtgaa tagagaatga gaagctactt agaattagta ccacaatatg caaaagtaca
    16021 taagaaaaaa aatagaacta caattttatg tattattatt gcagtatgct tagttactgc
    16081 tatctttgga cttgcagata tggctataca atgtcaaaag atacaattta ttaaagatga
    16141 tggaaattgg cacatagtaa ttagaaatat tgatgaaaag tttatatcag aaataaatag
    16201 tagagtagat atagctcacc atggtagggg gcaagtcgtt gacaatggag agtttaaatc
    16261 aaaggagatt ttgatacaag gtttagatga agaagtagca aagcaattta acttagaaat
    16321 aataaggggt cgttatccta ttggggagaa tgagacttta atagatgagg atgcagttaa
    16381 aagctttaat ctaaaaatag gagattttat caaaataaaa ttagcagatg gtagaaataa
    16441 aaattataag atagtaggtg aatattcatc aatatcaagc ttaagagcta cagataaaca
    16501 tggattaata ctttcaatat tgggtacaca agctattaaa aaatcagaaa cgtacgatta
    16561 ttattatatt acatttaaag aaaaggttaa tattagaaaa gccacttctg atattaaaaa
    16621 taccttcaat ttaagtgata aacaaattgg taaaaatgaa agattacttt ctattatagg
    16681 tcaaggtgac tctgactttt ctaaaccatt gtatttaaca gcaggattac tttttgtact
    16741 tgttttagta gcaagtatta tcatgatata taatagtttt aacatgagtg taattgagag
    16801 agttaaattt tttggtctgt tacgttgtct agggtcatca aaacatcaag ttaaaaaatt
    16861 tgttgtttta gaaagtttaa ttttaagtat aaaagctatt ccaataggct tagtattagg
    16921 aagtcttgta actattatat cttctatatt tcttaagtat gttaatgagt tattcagctc
    16981 aatgccaatt ttaaaagtta gttttattgg tattgcattt ggaataattg tagggttttt
    17041 aactgtaata ttatcagcta ttattccagc aaaaaaagct tcccgtgtat ctccacttag
    17101 cgctgtacgt gggaatctaa tgtccaaaga aattttaaat aacgggaaga caagtaaagt
    17161 tgcaaatata ggaagtttta aaattgagac ttctatggga ttaaatcatg ctttttcaag
    17221 aaagaaatct tttgtactta tgacttcttc atttgccatt agtattatac tatttttagg
    17281 ttttagtgtg cttatagacc ttatgtatca aggacttaag cctatgaagc cagaagctcc
    17341 tcatatatct attgttgacc ctaattttaa gtctgtttta actaaggaag atattaatga
    17401 aataagcaat atcaaaggag taaagaaagt atacagtaga atgatgacgg atatagaagc
    17461 tacatataat gggaagaaga caaaatcaca attaatttct tatgaaaagt atcaatttaa
    17521 ttgggcaaaa aaatatctat taaaaggaga agttaatgaa aataaactac agtcagaaaa
    17581 ccttgcatta gtagaagagg ggcatggatt tgatatagga gataagatat atattaaaaa
    17641 tggaaatgct gaaaaagagt tagaggtagg aggtatactt tcctcaattc catttgaggc
    17701 taaagataaa tatattggaa atattataac atctgaaaat acttttacga atataacagg
    17761 tataaagggt tatataataa tggatattca ggttgataaa gatactcctg gagatttaat
    17821 tgaaaatata agacgtgtag tagatgataa cttagaggtc agagataaaa gacaaagtaa
    17881 cttagaggtt aaaaattcgt tttatactat ggcaacattt gtatatggat ttgtgtttat
    17941 tattgcgatt ataagcatgt ttaatatcat aaatagcatg aatataagtg ttacaagtag
    18001 aaagaattac tatggtgtta tgcgtgcagt tggcatatcc aacagacaat taagaagaat
    18061 ggtaatagta gaggcaggtt catatgcagt gagtggttgt ttattaggta gtatactagg
    18121 attaatatta cataggtata tgtttatatc gttagtaagc tcaatgtttc atttagagtg
    18181 gcaagtacct tttaatttac tacttatcac tgtactaact atgataataa taactttatt
    18241 atcagtaaga aaaccaatca aaaagatttg tgaattagat ataatagact caataaatgc
    18301 acaataaata taggtattga tttaaattaa aaaaacgaag taaaaatgaa atagaaaata
    18361 tttttcattt ttacttcgtt ttttatatta taaaattttt gttatgttac aaaatttcta
    18421 taaagatgat gtgaatctaa acattatatg acaacgtgag catttaagtt aaaatatttt
    18481 aaatatacta ttttagataa gttccctctt catcttgata aattaatcct tttttcataa
    18541 gcactccaag agctcgttta aaatttttct tacttgaatt aaataatata gaaatatctt
    18601 tagggtcaga tttatcatta aatctcatat atccatcaga accttctaaa taacttaaaa
    18661 tcttattttc taaagtatca agttcatcct ttctatttcc tctaggagaa agaccaagtt
    18721 ttccatcttc atatattttt atgacatgta aattttcaag aacatcacca gtttttagtt
    18781 cagtaaagta ctcattatga agtattacac cagcatattt attgtctaca catatcattg
    18841 cagaattatt agtttggaat ccatatacaa ctccagttac aatatctcct acattgtaag
    18901 tatggtctgt taataagtat gaatctatat ctgtagtagc agcaattctt ttgcttttgt
    18961 ctaaatatat ataaaataaa tatttttcgt ctctaaatag tggataagtc ttagctttaa
    19021 aaggaactaa tatgtcttta ggaagtccca tatctataaa agtaccaatg tctgtattat
    19081 caactacttt taaatgtgct acatccccaa ccttagctaa aggcggtatt aaagttgcag
    19141 cagttctgtc atcagaatct ttaaatatga aagcatttac ttcatcacct atgtttattt
    19201 cattttttcc gattaatcta ttatgaagaa gtatatcgtc ttttgtgtta ttagtttgtc
    19261 catccaaaaa atatccaaat tcagtttttc tttttactgt aagtttatta aaatcaccta
    19321 tgtttatcaa attaaaatca tcctctcatt ttatatttat aatttagcca taatatactt
    19381 atgtagtagt ttgtcacagt atctatatta gtattagtga aatttacaat aaataatata
    19441 gttatttatg tatttttcaa ttctctagct tcttatatag tataaactcc aatttctttt
    19501 ttgtctttag gttttattaa aatttttaca aaataagtta aaaagtattg aaataaaatt
    19561 tcttttaaag tataattggt atataccaaa attggtatat accatatcga aaagtggtga
    19621 ctatatgaaa atagtaaata aatctagtaa tataccattg catactcaat taagttcaat
    19681 aataagagag atgatagaaa ctggtgagct taaagagggc gatgcaataa tgccagaaag
    19741 agaactttgc aacatacaaa atgtaagtcg tatgacagta aataaaacca ttgttggatt
    19801 agttacagaa ggacttcttt atagggtaca aggtaaaggg acattcgttg caaagcaaaa
    19861 aaagaagtat cagttttcaa atgtaaaagg ttttactgat gttatgaaag aaaagggagt
    19921 aaacataaaa acggatatat tatcctttga gatggaacta ccagatgatt tagttaaaag
    19981 aaagcttgga ataagtgata atactacaaa tatatataag attgtcagac ttagatatac
    20041 tgatggagag ccatttggat tagaaatagt atatctatca gaagaaatgt gtaagggtct
    20101 aacaaaaggg atattggata attcttcatt atatagggtt ttaaatgaaa aatatggcta
    20161 taagatacaa aaagctgaac aggtaatgga gccagtaata ctttcagatg aagaaagtaa
    20221 gcttcttgaa acagatgaag gtgctttagc tcttaaactt catagaaatt cctataatag
    20281 agaaggtaga cctatagaat ataccatatc aatatttaga acagataaat atcaatatga
    20341 aatagtattg agtgagtagg tgaataatat gaaatgttta attaatggaa agataatatt
    20401 aaaaaatcaa atcttagaaa ataaagtatt agtatttgat gaaaaaataa ttgatatagc
    20461 tgatagtgta ccaaaagatt gtgaagttat agatgctgat ggaaaatata tatctccagg
    20521 gcttattgat attcatatac atggaaacat gggaaaagat acaatggatt cgactgatga
    20581 atctattgaa acaatttcaa aatcaattat gagacatgga gtaacatctt ttcttccaac
    20641 tacaatgact atggataaag aacatgttta tgatgcactt gaagttatta aaaaagccca
    20701 aaatagaaag cttgaagggg cacaagtatt aggagcacat ttagaaggac cttttataaa
    20761 tgagaattat aagggagcac aaaatgaaaa atttataata aattcaaaat acgaatttat
    20821 aaaagaatat aaagatgtta taaaagttat aacttatgct ccagaaaaag atattgattt
    20881 tgattttact agagaaataa aaagatgtac agatatagtt ttatctattg gtcatagtaa
    20941 tgcaaattat gaccaagcta aagaagctat aaatttagga gtaactaatg taactcacat
    21001 gttcaatgca atgactggtt taaaccatag agacccaggc gttgttggtg cagcacttac
    21061 aactaatgtg tacagtgagt taatagcaga tacaatccat ataaataaag atttatttca
    21121 atttatacta aataataaag gaaaagaaag actgatttta ataacagatt ctatagaagc
    21181 tggtggtctt gaagatggca attattctct tggaggtcag aaagtcatag ttaagggtaa
    21241 tgaagctaga cttgaaaatg gagcattagc tggaagtgtg ttgtctttaa ataaaatggt
    21301 atttaacttc ttaaataata caaaccttaa agtgaatgaa gcaattaatt tagcttcttt
    21361 aaatccagca acatctttgg gaataaatga caaaaaagga agcttagaaa taggtaagga
    21421 tgcagatata gctgtatttg atgagaattt agattgtaaa atgacacttt gcttggggga
    21481 agtagtatat aaaaatatat agtatacaaa acaaacctta aagacagtaa aaacaatata
    21541 aaaaataata aattaaactt acattagtaa aagtagtagt taaaatttag gaggaataag
    21601 atgagagtat tagtgtgtaa agattatgat ggaatgagta aaaaagccgc tgaaatgata
    21661 gcagctcaaa tagttttaaa accaaattca atactgggac tagctacagg aagtacacca
    21721 gtaggtatgt atagagattt agtaaaaaaa tacaatgata atatagtaga tttttcagat
    21781 gtgatgagct ttaatttaga tgaatattat aagttaccaa tatctaatga ccaaagctat
    21841 gattatttta tgaaagagaa tctatttaat catgtaaaca taaagccaga aaatactcat
    21901 ctaccaaatg gaatggctga tgatattgaa aaagagtgta tgaactatga agcttctata
    21961 gatgcagctg gtggtataga tgtacaagta cttggaatag gtcgtaatgc tcatataggt
    22021 tttaatgaac ctgatactaa atttgcaaaa agaactcatg tagttgaact tacagaatct
    22081 acaatagaag ctaatgcaag attctttaaa tcaagagaag atgttcctaa aaaagctgta
    22141 agtatgggaa taggttcaat attgaagtct aagaaaatat tgcttttagc ttcaggagaa
    22201 gaaaaagctg atgcagtata taatactgtt tacggagata taactccaga agttcctggt
    22261 tctatacttc aacttcataa agacactata gttatagtag atgaagcagc agcaagtaaa
    22321 ttgaatccaa aagattataa attagtataa gaatagaatg tagtttaaat aaaaaatagc
    22381 tatcattgaa taatcaaatt tatttaatga tagctatttt tatttaaatt agttattatt
    22441 gtttaaatta cttgcttatt actttttacg aaaactcgtt atcaagaagt atccaaataa
    22501 gatgttaaaa attattatgt ttagtgggat tctatcaagc ataataaaat tacctataat
    22561 tgggatatta ccaactggaa acataaagaa gaatacaggc atcagtgata gtaaaaaaga
    22621 tggaaaacaa agaagaagta atcttggaat atcaatatac caactaccat cctttttgta
    22681 ttctctaatc aataattcag ttcctagtaa taaaccaata ccaccagagg aaattaaatt
    22741 aataaaaatg tatcttttaa agtcttgcat ataaccagtg taaaattgag tatagaaatc
    22801 ataatttaat ttaacggcta aaaaatacat aagcaataga atgattaaaa ataaaagata
    22861 tctaagagct tttttcattt taaattctcc cttcagaaat actttattta gttttatttt
    22921 gttggaatct gattttatca tttagtttaa gaaatccata atattagtga agaatgaaat
    22981 aagtattata tatgaataaa tatttttaga attaaggtga att
//
LOCUS       DAEPKC010000063        22316 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.063, whole genome shotgun sequence.
ACCESSION   DAEPKC010000063 DAEPKC010000000
VERSION     DAEPKC010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22316)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22316)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22316
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.063"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..369
                     /gene="tuf"
                     /locus_tag="KR294_002434"
     CDS             <1..369
                     /gene="tuf"
                     /locus_tag="KR294_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887863.1"
                     /note="EF-Tu; promotes GTP-dependent binding of
                     aminoacyl-tRNA to the A-site of ribosomes during protein
                     biosynthesis; when the tRNA anticodon matches the mRNA
                     codon, GTP hydrolysis results; the inactive EF-Tu-GDP
                     leaves the ribosome and release of GDP is promoted by
                     elongation factor Ts; many prokaryotes have two copies of
                     the gene encoding EF-Tu; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HBH0240504.1"
                     /translation="DNIGALLRGVQRNEIERGQVLAKTGSVKAHTKFTAEVYVLKKEE
                     GGRHTPFFDGYRPQFYFRTTDVTGACKLPEGIEMVMPGDNVTMEVDLINSIVVEEGLR
                     FSIREGGRTVASGVVATIIE"
     gene            741..1052
                     /gene="rpsJ"
                     /locus_tag="KR294_002435"
     CDS             741..1052
                     /gene="rpsJ"
                     /locus_tag="KR294_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HBH0240505.1"
                     /translation="MAKNEKIRIRLKSYDHKLLDFSAGKIVETAKKAGSQVSGPVPLP
                     TEKQVVTILRAVHKYKDSREQFEIRTHKRLIDIANPTPKTVDSLMRLDLPAGVDIEIK
                     L"
     gene            1144..1773
                     /gene="rplC"
                     /locus_tag="KR294_002436"
     CDS             1144..1773
                     /gene="rplC"
                     /locus_tag="KR294_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HBH0240506.1"
                     /translation="MKGILGKKVGMTQIFTDKGVVIPVTAVEAGPMVVTQIKTVDKDG
                     YNAIQIGFEDAKEKALNKPKKGHLAAANVLKKHLKEFRVDSVEGYTVGQEIKADVFEA
                     GAKIDVTGISKGKGFQGPIKRHGQSRGPETHGSRYHRRPGSMGACSYPGRVFKNKKLA
                     GHMGSVKVTVQNLEVVKVDADKNLILVKGAIPGAKGSVVTIKEAIKVSK"
     gene            1803..2426
                     /gene="rplD"
                     /locus_tag="KR294_002437"
     CDS             1803..2426
                     /gene="rplD"
                     /locus_tag="KR294_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001127258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HBH0240507.1"
                     /translation="MPKLNVLNVSGQNVGEIELSDSIFGVEVNGHVLYEVVKNQLANK
                     RQGTQSAKTRAEVRGGGRKPWKQKGTGRARQGSTRSVQWVGGGVAFAPKPRSYKYTLP
                     KKVRRLAMKSALSSKVQNSEVIVLDALNMDAPKTKEFAQILNNINAAKKALVVIADKN
                     DNVIKSARNIEGVQTALVNTMNVYDILKYDSFIITTDAVKKVEEVYA"
     gene            2426..2716
                     /gene="rplW"
                     /locus_tag="KR294_002438"
     CDS             2426..2716
                     /gene="rplW"
                     /locus_tag="KR294_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HBH0240508.1"
                     /translation="MTNPHDVIIRPVVTEHSMAEMGEKKYTFVVAKDANKTEIKKAVE
                     KVFGVSVDKVNTLNYDGKVKRMGRTQGRTSSFKKAVVKLTADSKEIEFFQGM"
     gene            2746..3576
                     /gene="rplB"
                     /locus_tag="KR294_002439"
     CDS             2746..3576
                     /gene="rplB"
                     /locus_tag="KR294_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HBH0240509.1"
                     /translation="MAIKKFRPTSPALRQMTVLVSDEITCNQPEKSLLVNLKKNAGRN
                     VHGRITVRHRGGGQKRKYRIIDFKRDKDGIPAKVATIEYDPNRTANIALLNYADGEKR
                     YILAPVGINVGDTILSGLGADIKPGNCLALKDMPVGTIIHNIELKPGKGAQLVRSAGV
                     SAQLMAKEGKNALLRLPSGEMRLVSINCKATIGQVGNIEHGNVVIGKAGRKRHMGIRP
                     TVRGSVMNPNDHPHGGGEGRSPIGRPSPVTPWGKPALGYKTRKKNKASNKLIVSRRTK
                     "
     gene            3611..3892
                     /gene="rpsS"
                     /locus_tag="KR294_002440"
     CDS             3611..3892
                     /gene="rpsS"
                     /locus_tag="KR294_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003454422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HBH0240510.1"
                     /translation="MSRSTKKGPFVHARLLKKIEAMNASGNKEVIKTWSRSSTVFPQM
                     VENTIAVHDGRKHVPVYITEDMVGHKLGEFVPTRTFKGHKDDEKSNKRK"
     gene            3924..4259
                     /gene="rplV"
                     /locus_tag="KR294_002441"
     CDS             3924..4259
                     /gene="rplV"
                     /locus_tag="KR294_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HBH0240511.1"
                     /translation="MEAKATAKYVRVSPRKAGQICDLVRGKNVDEALAILKFTPRGAA
                     SIIAKVVKSAKANAENNHEMDTEKLYIASIVANQGPTMKRFMPRAMGRATTIRKRTSH
                     IEVVVKEKK"
     gene            4282..5097
                     /gene="rpsC"
                     /locus_tag="KR294_002442"
     CDS             4282..5097
                     /gene="rpsC"
                     /locus_tag="KR294_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HBH0240512.1"
                     /translation="MGQKVNPHGLRVGVIKDWDSRWFATDKKEFGNLLLEDHNIRKFL
                     KKRLYSAGVAKIEIERSANKIKMDLHVAKPGVVIGRAGAGIEALKAELEKMTKKTIIV
                     NIVEVRSTDKNAQLVAENIALAIERRVAFRRAMKQAIQRAMKSGAKGIKVSASGRLGG
                     AEMARTEGYSEGNVPLQTLRADIDYGFAEADTTYGKIGIKVWICNGEVLPTRDGVNPR
                     EESRKSDRRDNKRDNRRNDRRGNDRRGNDNRGNYRGQRPQGGSRPQRTENKGN"
     gene            5133..5564
                     /gene="rplP"
                     /locus_tag="KR294_002443"
     CDS             5133..5564
                     /gene="rplP"
                     /locus_tag="KR294_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HBH0240513.1"
                     /translation="MLMPKRVKRRRVHRGSMAGQAHKGNKVTYGEFGLVALEASWITS
                     NQIEAARIAMTRYIKRGGKVWIKIFPHKPVTRKPAETRMGAGKGSPEYWVAVVKPGRV
                     MFELAGVSEDKAREAMRLAAHKLPIKCKFVKKEDLEVKGGE"
     gene            5566..5769
                     /gene="rpmC"
                     /locus_tag="KR294_002444"
     CDS             5566..5769
                     /gene="rpmC"
                     /locus_tag="KR294_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005810148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HBH0240514.1"
                     /translation="MKAKELRDLTSEELMNKLNDFKSELFSLRFQLATGQLENTARIK
                     FVKKDIAKVKTVLAERKLYETRA"
     gene            5793..6047
                     /gene="rpsQ"
                     /locus_tag="KR294_002445"
     CDS             5793..6047
                     /gene="rpsQ"
                     /locus_tag="KR294_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HBH0240515.1"
                     /translation="MERGRRKVRIGRVVSDKMDKTIVVAVEEFVRHPLYNKRVKRTKK
                     FKAHDEKNICNIGDRVKIMETRPLSKDKRFRLVEVVEKVK"
     gene            6073..6441
                     /gene="rplN"
                     /locus_tag="KR294_002446"
     CDS             6073..6441
                     /gene="rplN"
                     /locus_tag="KR294_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007885948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HBH0240516.1"
                     /translation="MIQQESRLRVADNSGAKELLCIRVLGGSKRRYGNIGDVIVATVK
                     SATPGGVVKKGKVVKAVIVRSKQGVRRNDGSYISFDENAAVIIKDDKTPVGTRIFGPV
                     ARELRDNEFMKIVSLAPEVL"
     gene            6465..6770
                     /gene="rplX"
                     /locus_tag="KR294_002447"
     CDS             6465..6770
                     /gene="rplX"
                     /locus_tag="KR294_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HBH0240517.1"
                     /translation="MRVKKGDTVVVIAGKDKGKKGSVLKVYPKTSKVLVEGVNVITKH
                     QKPSAMNQQGGIINKEAPIHISNVMPFDPETGKGVRVRYEVKDGNKVRVSAKSGKEL"
     gene            6800..7342
                     /gene="rplE"
                     /locus_tag="KR294_002448"
     CDS             6800..7342
                     /gene="rplE"
                     /locus_tag="KR294_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HBH0240518.1"
                     /translation="MASRLQEKYMKEVAPALMEKFGYKNVMEIPKLNKIVINMGIGDA
                     RENPKGLEKGVEELEMISGQKPVITKARKSVANFKLREGMPIGTKVTLRADKMFYFMD
                     KLVSVSLPRVRDFRGVNPNAFDGRGNYALGVKEQLIFPEIEYDKIDKVRGMDIIFVTT
                     AKTDEEARELLKLLGMPFSK"
     gene            7360..7545
                     /locus_tag="KR294_002449"
     CDS             7360..7545
                     /locus_tag="KR294_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HBH0240519.1"
                     /translation="MARKAMVVKQQRKQKYATREYTRCTICGRPHSVLKKFGICRICF
                     RELAYKGQIPGVRKASW"
     gene            7578..7976
                     /gene="rpsH"
                     /locus_tag="KR294_002450"
     CDS             7578..7976
                     /gene="rpsH"
                     /locus_tag="KR294_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012158382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HBH0240520.1"
                     /translation="MTMTDPIADMLTRIRNANVVKHETVDVPASNMKKELARILLEEG
                     FIRGYDVIEDGKQGIIRIQLKYGQEGERVITGLKKISKPGMRVYAANHEIPKVLNGLG
                     ISVISTSKGILTDKQARKENVGGEVICYVW"
     gene            8007..8549
                     /gene="rplF"
                     /locus_tag="KR294_002451"
     CDS             8007..8549
                     /gene="rplF"
                     /locus_tag="KR294_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HBH0240521.1"
                     /translation="MSRIGVKPIIIPAGVEVTIAEGNLVTVKGPKGTLTKQLSAELNI
                     KKEENTIMVERPTDNKKHRSLHGLTRTLLDNMVVGVNTGFEKKLELKGVGYRAQKQGK
                     KLVMNLGFSHPVEMEDPEGITVEAPNQTELIVKGIDKQLVGNYAAKIRAWRKPEPYKG
                     KGIKYVDEVIRRKEGKTGKK"
     gene            8585..8953
                     /gene="rplR"
                     /locus_tag="KR294_002452"
     CDS             8585..8953
                     /gene="rplR"
                     /locus_tag="KR294_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HBH0240522.1"
                     /translation="MLKKADKNANRLQRHKRVRRKISGTSQRPRLCVFRSANNIYAQI
                     IDDTKRVTLVAASSLEAEVKSAVNHTGNKEAAKKVGELVAKKAVEKGITEVVFDRGGY
                     LYHGRIQELAEGAREAGLKF"
     gene            8974..9483
                     /gene="rpsE"
                     /locus_tag="KR294_002453"
     CDS             8974..9483
                     /gene="rpsE"
                     /locus_tag="KR294_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011109776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HBH0240523.1"
                     /translation="MLRRKPIDAGQLDLQEKVVEVRRVTKVVKGGRNFRFAALVVVGD
                     ENGHVGIGAGKAMEVPDAIKKAVEDAKKNLIVVPIVGTTIPHEVRGHFGAGNILIMPA
                     VEGTGVIAGGPARAVLELAGLKDVRAKSLGSNNPRNMVNATIEGLNSLKTVEDIAKLR
                     GKKVEELLG"
     gene            9498..9683
                     /gene="rpmD"
                     /locus_tag="KR294_002454"
     CDS             9498..9683
                     /gene="rpmD"
                     /locus_tag="KR294_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HBH0240524.1"
                     /translation="MAKLQIKLVRSVIGTTPNQKKNVEALGLRKREQVVVKEDNAQTR
                     GMINKVSHLLEVTEIAE"
     gene            9716..10159
                     /gene="rplO"
                     /locus_tag="KR294_002455"
     CDS             9716..10159
                     /gene="rplO"
                     /locus_tag="KR294_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HBH0240525.1"
                     /translation="MKLHELKPAEGAVRAKRRLGRGTATGQGKTAGRGQKGQWSRSGG
                     GVRVGFEGGQMPLARRLPKRGFNNIFKKVYTEVNVEVLNRFENGTEITAELLKSTKTI
                     SKIGKDGIKILGEGNLEKALTVKAAKFTASAQEKIEKAGGKAELV"
     gene            10203..11471
                     /gene="secY"
                     /locus_tag="KR294_002456"
     CDS             10203..11471
                     /gene="secY"
                     /locus_tag="KR294_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HBH0240526.1"
                     /translation="MLSKLKQAWKIKAVRKKVMYTLMMIVIFRIGTTIPVPGIDTSII
                     QKMVGGNSLLSLYNMFTGGAFSNFSLFALGISPYITASIIIQLLTVGFESLAELQKSG
                     EEGKKKINKYTKYTALALAVVQALGITLGIVRSALISNSVFFITTVVITLVSASMLVM
                     WIGDKITEKGIGNGSSVIIFAGIISRIPTDVIKISQQVKSGEVAPWVIVILAVVILLT
                     VTGVTFIQEATRKIPVQYAKRVVGRKMYGGQSSHIPMKVNQSGVMPIIFASSLLAFPQ
                     TIAMFMGPNAQAFVQKYLSMATEQGFWTYRSIEILLIIFFSYFYTTVSFNTEDISKNM
                     KNNGGFIPGIRPGEPTMDYLNRILTRLTLAGATFLAIIAMVPALTTHYMKVNMSLAGT
                     SLLIVVGVALELKRQLESNLVMRSYQGFLK"
     gene            11488..12138
                     /locus_tag="KR294_002457"
     CDS             11488..12138
                     /locus_tag="KR294_002457"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HBH0240527.1"
                     /translation="MRIILLGPPGAGKGTQAAGIVEKYNIPHISTGDIFRKNIKEGTE
                     LGKKAKEYMDQGLLVPDELTVGLVTDRISQEDCKNGFMLDGFPRNVAQGEHLDIFLKN
                     AGISLDKVVNIEVDKSILVSRAVGRRICKSCGATYHVEFNPPKVEGVCDVCQGELYQR
                     ADDNEETVSKRIQVYLDETKPLVDYYSKQGIIADIKGDQAIDKVFEDIVAALGSGK"
     gene            12139..12885
                     /gene="map"
                     /locus_tag="KR294_002458"
     CDS             12139..12885
                     /gene="map"
                     /locus_tag="KR294_002458"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HBH0240528.1"
                     /translation="MIILKSKKEIELLREAGKIVADTHEVLRKAISPGISTLELDKIA
                     EENIRKYNAEPSFKGYGGFPGSICASINREVVHGIPGETILQEGDIVSLDIGAYYKGY
                     HGDSAKTHGVGMISEEDRKLIEVTRESFYEGIKFAKLGYRLSDISHAVQTHVEKHGFS
                     VVRDLVGHGVGANLHEDPQVPNYGLPGKGPRLREGMVIAIEPMVNAGRYHVKTLSDGW
                     TTVTIDGKKSAHYEHTIAITEHEPLILTKL"
     gene            12907..13176
                     /locus_tag="KR294_002459"
     CDS             12907..13176
                     /locus_tag="KR294_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KOW domain-containing protein"
                     /protein_id="HBH0240529.1"
                     /translation="MLSDNLSIGQVVKVSLGRDKGNLFFVVKIINNEYVLIADGKKRK
                     LDKPKLKKVKHLKKYNFINDEVRKRVVSGQEITDSFLRAELTKLN"
     gene            13214..13432
                     /gene="infA"
                     /locus_tag="KR294_002460"
     CDS             13214..13432
                     /gene="infA"
                     /locus_tag="KR294_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001029884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HBH0240530.1"
                     /translation="MAKKDVIELEGTVSEALPNAMFKVKLENGHEILCHISGKLRMNF
                     IRILEGDKVNVELSPYDLTRGRITWRKK"
     gene            13468..13581
                     /gene="rpmJ"
                     /locus_tag="KR294_002461"
     CDS             13468..13581
                     /gene="rpmJ"
                     /locus_tag="KR294_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HBH0240531.1"
                     /translation="MKVRPSVKPICEKCKVIKRKGKVMVICENPKHKQKQG"
     gene            13734..14105
                     /gene="rpsM"
                     /locus_tag="KR294_002462"
     CDS             13734..14105
                     /gene="rpsM"
                     /locus_tag="KR294_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005810116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HBH0240532.1"
                     /translation="MARIAGVDLPREKRAEIGLTYIYGIGKATANEILAKAEINPDTR
                     IKDLSEDQVNELRKVIDDDFLVEGDLRREIALNIKRLRDIKCYRGIRHAKGLPLRGQR
                     TKTNARTRKGPRKTVSRKKKK"
     gene            14141..14539
                     /gene="rpsK"
                     /locus_tag="KR294_002463"
     CDS             14141..14539
                     /gene="rpsK"
                     /locus_tag="KR294_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006440523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HBH0240533.1"
                     /translation="MAKPKKKVTRIRRRERKNIERGHAHIQSTFNNTIITLTDVHGNA
                     ISWASSGQLGFKGSRKSTPFASQMAAETAAKAAMEHGLKSVEVFVKGPGSGREAAIRA
                     LQATGLEVTMIKDVTPIPHNGCRPPKRRRV"
     gene            14571..15194
                     /gene="rpsD"
                     /locus_tag="KR294_002464"
     CDS             14571..15194
                     /gene="rpsD"
                     /locus_tag="KR294_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HBH0240534.1"
                     /translation="MARYTGASCRQCRREGMKLFLKGDRCYTDKCAIVKRNYAPGQHG
                     QGRKKVSNYGLQLREKQKVKRIYGVLETQFRNLYERAENMPGKAGENLLSLLERRLDN
                     VVYRMGLASSRKEARQLVTHGHFTLNGNKVDIPSLIVKVGDVIEVKEKSRSSAKFKNL
                     VEVNSRIAPKWLEANVEGMTAKVVGVPTREDIDLEIAEHLIIELYSK"
     gene            15272..16219
                     /locus_tag="KR294_002465"
     CDS             15272..16219
                     /locus_tag="KR294_002465"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HBH0240535.1"
                     /translation="MIEIEKPKVDIVELSEDYRYGKFVIEPLERGYGITIGNALRRIL
                     LSSLPGVAVNAIKIDGVLHEFSTIPGVKEDVTEIILTLKELSATIDGEGSRTLKIEAQ
                     GPCSITGADIICPPDVEILSKDLAIATLDDNAKLNMEIFVDKGRGYVSAEENKTENVP
                     IGVLPVDSIYTPVEKVSYHVENTRVGQKTDYDKLVLEVWTNGSINPQEGISLAAKVLV
                     EHLNLFIDLTEHVSSVEIMVEKEEDQKEKVLEMTIEELDLSVRSYNCLKRAGINTVEE
                     LANKSEDDMMKVRNLGKKSLEEVIQKLEELGLGLKPSEE"
     gene            16240..16581
                     /gene="rplQ"
                     /locus_tag="KR294_002466"
     CDS             16240..16581
                     /gene="rplQ"
                     /locus_tag="KR294_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003357477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HBH0240536.1"
                     /translation="MAKYRKLGRETAHRNLMLRNLVTCLLRSGRIETTVTRAKETRRM
                     AEKMITLAKRGDLHARRQVLAYVMDETVVNNLFTDLAPKYAERNGGYTRIIKIGPRKG
                     DAAEMAFIELV"
     gene            16701..17534
                     /locus_tag="KR294_002467"
     CDS             16701..17534
                     /locus_tag="KR294_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HBH0240537.1"
                     /translation="MDNIVKVNNISFEYITDEAKLKAIDNLSLDVKKGEFVAIIGHNG
                     SGKSTLSKNLNAILMPTEGNILIDDMDTKEEERLWDIRQTAGMVFQNPDNQIVATIVE
                     EDVAFGPENLGIEPKEIRRIVEESLKSVGMYDLRDRQPHLLSGGQKQRVAIAGIIAMR
                     PKCIIFDEATAMLDPSGRKEVMKTIKRLNKEENITVIHITHFMEEAVEADRVVVMEKG
                     KKILEGTPREVFSKIKMLKEIGLDVPCMTELSSLLIEEGINISSDILTVDEMVMELCQ
                     L"
     gene            17522..18388
                     /locus_tag="KR294_002468"
     CDS             17522..18388
                     /locus_tag="KR294_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HBH0240538.1"
                     /translation="MSIIVKNLTHIYNEGMPFASKALDDVSFEIKDRDFVGLIGHTGS
                     GKSTLIQHLNGLLKPSSGEIFINDFNITDKNLNLTEIRKRVGVVFQYPEYQLFEETID
                     KDIAFGPSNLGLEESEIHNRVKASMEAVGLDYEGFKDKSPFELSGGQKRRVAIAGVIA
                     MNPEVLILDEPTAGLDPGGRDEIFNLIKDLHEKKNMTIILSSHSMDDMAKLAKTLIVM
                     NHGSVEFMGTPREVFKSNASKLKDIGLDIPQVLELALKLREKGFDISEDILTLEEAKQ
                     EILKVVRGRGLC"
     gene            18382..19185
                     /locus_tag="KR294_002469"
     CDS             18382..19185
                     /locus_tag="KR294_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HBH0240539.1"
                     /translation="MLKDITIGQYYPTSSAIHKLDPRIKLVATIVFMVSIFVVNKFWP
                     YIVVLLCLLAMIKLANIPVKYIVKGVKPLKWIILFTFLINIFFLPGDEIWSFGFLAIT
                     KQGLRQAIFMAIRLIFLVVGTSLLTLTTSPIELTDGIERLLNPFKKIGLPVHELAMMM
                     TIALRFIPTLLDETDKIMKAQMSRGADFESKNLINRAKNLVPLLVPLFVSAFRRADEL
                     AMAMEARCYRGGHNRTKMRESVISRRDYMACVFQVVYLGAIIATRFIAI"
     gene            19217..19948
                     /gene="truA"
                     /locus_tag="KR294_002470"
     CDS             19217..19948
                     /gene="truA"
                     /locus_tag="KR294_002470"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003514691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HBH0240540.1"
                     /translation="MRNIKIKIQYNGKNYCGWQKQPDSLGIQGTIERAIYDITKEETS
                     LIGSGRTDSGVHAIGQIANFKINSGISIESIPMALNAKLPKDISVIEACEVNDDFHSR
                     YSAKGKTYKYLVYNSKFRNPILSEISYQVKYELDFDKMCSEAKSLLGTHDFKGFMSSG
                     SSVKDTVRTIYDIDISKKDDLITFEISGNGFLYNMVRIIVGTLVDMGRGRINEPFLDI
                     IQSKTRSRCGHTAPAQGLFLKKVHY"
     gene            20068..20499
                     /gene="rplM"
                     /locus_tag="KR294_002471"
     CDS             20068..20499
                     /gene="rplM"
                     /locus_tag="KR294_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HBH0240541.1"
                     /translation="MKSYIAKPADVQRKWYLVDAEGKTLGRLATEIATVLRGKHKPTF
                     TPHVDGGDFVVVVNAEKIVLSGKKLDQKYYRYHTGYVGGLKEISYRDMMDKKPEEVIS
                     HAVSGMLPKNKLRSRMMTRLRVFAGAEHTHAAQNPEVLNFK"
     gene            20528..20920
                     /gene="rpsI"
                     /locus_tag="KR294_002472"
     CDS             20528..20920
                     /gene="rpsI"
                     /locus_tag="KR294_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003515879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HBH0240542.1"
                     /translation="MANVQYYGTGRRKSSVARVRLVAGEGNILVNGRALENYFNYETL
                     IRDVKQPLVLTGNENKYDVIVKVEGGGFTGQAGAIRHGISRALLKADLDLRPALKKEG
                     FLTRDARMKERKKYGLKAARRAPQFSKR"
     gene            21379..22131
                     /gene="cwlD"
                     /locus_tag="KR294_002473"
     CDS             21379..22131
                     /gene="cwlD"
                     /locus_tag="KR294_002473"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase CwlD"
                     /protein_id="HBH0240543.1"
                     /translation="MEYYSVFISIHIQGDVVRKYIKHIIFSFAMICLVVVSIFEIKNI
                     SEDVIKYMPVTNKTIILDAGHGGIDPGALNKDKSTSEKDINLAITLKLRELIESSGGL
                     VILTREDDSSLYKEENNKTTRQKYNENLKNRKEIISNSNANMFVSIHLNAFEQSKYYG
                     AQTFYPKDKQDSKELSKCIQEELKRVVDKTNNREVKPRDDIYLLKENNIPSVLIECGF
                     LSNEKECKLLTDETYQEKIAWAIYIGIQKYLS"
BASE COUNT         8972 a         2609 c         4585 g         6150 t
ORIGIN      
        1 gataatatag gagcattatt aagaggagta caaagaaacg agatagaaag aggacaagta
       61 ctagcaaaga ctggatcagt aaaggcacac acaaagttta cagcagaagt atatgtactt
      121 aaaaaagaag aaggtggaag acatacacca ttctttgatg gatatagacc acaattctat
      181 ttcagaacaa cagacgtaac aggagcttgt aagttaccag aaggaataga gatggtaatg
      241 cctggagata acgtaacaat ggaagtagac ttaataaact caatagttgt agaagaggga
      301 ttaagattct caataagaga aggtggaaga acagtagctt caggagttgt tgctacaata
      361 atagagtaat cctttactaa actaatggat ttaatataaa aaaagagggg ggtaactcct
      421 ctcttttttg ttttttgttg acaagtagcg ctaaagcata tatactaaac tagtgccttg
      481 agacagatta acaatcaagt ttaaggttat gatgttgtaa tagaaaataa aattgaaaaa
      541 aacagaaaaa aaacttgaaa aaatgtaaca gatgatataa aatataatag tgtgcttgag
      601 agattaagaa aataataatt aaatcctagt gaaatacgaa ctgatatcga tttaaaagtt
      661 acaacacacc cggagcagtg tatcggtatt ggttgtacgc aacttgaaaa ttaaacacgt
      721 gataaaggag ggaaaacaaa atggctaaga atgaaaaaat aagaataaga ttaaaatcat
      781 atgatcacaa attattagat ttttcagcag gtaaaatagt tgaaactgct aaaaaggctg
      841 gatcacaagt ttcaggacct gtgcctctac caacagaaaa acaagttgta actatattaa
      901 gagctgtaca taagtacaaa gactctagag aacaatttga aataagaact cataaaagac
      961 taatcgacat agctaatcca acacctaaga cagttgactc attaatgaga ttagacttac
     1021 cagcaggtgt agatatagaa ataaaattat aagaacccct aagatattat cctatagatg
     1081 attatcttag aatgattact ctaaaagatg taatccgctg taagaattat aggaggtgct
     1141 aatatgaaag gaatattagg caaaaaagtt ggtatgactc aaatattcac tgataaaggt
     1201 gtagttatac ctgtaacagc tgttgaagca gggcctatgg tcgttactca aataaaaaca
     1261 gttgataaag atggatacaa tgctatacaa ataggttttg aagatgctaa agaaaaagct
     1321 ttaaacaaac ctaaaaaagg acatttagct gctgctaatg ttttaaagaa acatttaaaa
     1381 gaatttagag tagattctgt agaaggatac acagtaggac aagaaataaa agctgatgta
     1441 tttgaagcag gtgcaaaaat agatgttact ggaataagta aaggtaaggg attccaaggt
     1501 ccaataaaaa gacatggaca aagtagaggt cctgaaactc acggttctag ataccacaga
     1561 agaccaggtt caatgggagc ttgttcttac ccaggtagag tatttaaaaa caaaaaatta
     1621 gctggacata tgggaagcgt aaaggtaaca gttcaaaact tagaggttgt taaagtagat
     1681 gctgacaaga accttatatt agttaaagga gctataccag gagctaaagg ttcagtagta
     1741 actataaaag aagctataaa ggtttctaaa taatgactaa cctagagaaa ggaggaataa
     1801 caatgccaaa attaaatgta ctaaatgtta gtggacaaaa cgttggagaa atagaattat
     1861 cagattctat atttggcgta gaagttaatg gacatgtttt atacgaagtt gtaaaaaatc
     1921 aattagcaaa taagagacaa ggaactcaat ctgctaaaac tagagcagaa gttagaggtg
     1981 gcggaagaaa accttggaaa caaaaaggaa caggtagagc aagacaaggt tctacaagat
     2041 ctgtacaatg ggtaggtgga ggagttgctt ttgcacctaa accaagaagc tacaaatata
     2101 cattacctaa gaaggtaaga agattagcta tgaagagtgc tttatcttca aaagttcaaa
     2161 atagtgaagt tatagtatta gatgcattaa acatggatgc tcctaagact aaagaatttg
     2221 ctcaaatatt aaacaatata aatgctgcta aaaaagcttt agtagttata gctgacaaaa
     2281 acgataacgt aataaaatca gctagaaata tagaaggtgt tcaaactgca ttagttaata
     2341 ctatgaatgt atatgatata ttaaaatacg attcatttat aataactaca gatgctgtta
     2401 aaaaagtgga ggaggtgtac gcataatgac taatccacat gatgtaataa taagaccagt
     2461 tgtaactgag cacagtatgg ctgaaatggg tgaaaaaaaa tacacttttg ttgtggctaa
     2521 agatgcgaac aaaactgaaa taaaaaaagc agtagaaaaa gtattcggag ttagtgttga
     2581 taaagtaaat actttaaact acgatggaaa agttaaaaga atgggtagaa ctcaaggaag
     2641 aacatcaagc tttaagaaag cagtagttaa attaactgct gatagtaaag aaatagaatt
     2701 cttccaagga atgtagtatt ataacaaacg aaggagggaa aacagatggc tataaaaaag
     2761 tttagaccaa cttctcctgc cttaagacaa atgacagttt tagtttctga tgaaataaca
     2821 tgtaatcaac cagaaaaatc tcttttagtt aacttaaaga aaaatgctgg tagaaacgta
     2881 catggtagaa taactgttcg tcatagaggt ggaggacaaa aaagaaaata tagaataata
     2941 gattttaaaa gagataaaga tggtatacct gctaaggttg ctactataga atatgatcca
     3001 aacagaactg caaatatcgc attattaaac tatgctgatg gagaaaaaag atatatatta
     3061 gctccagttg gaattaatgt tggagatact atattatcag gattaggtgc tgatataaaa
     3121 ccaggaaact gtttagcatt aaaagatatg ccagttggta ctatcattca taatatagaa
     3181 ttaaagccag gaaaaggagc tcaattagtt agatctgctg gagtttctgc acaattaatg
     3241 gctaaagaag gaaaaaatgc tttattaaga ttaccatcag gtgagatgag attagtaagc
     3301 ataaactgta aagctactat aggtcaagtt ggaaatatag agcatggtaa cgtagttatc
     3361 ggtaaagcag gtagaaaaag acatatggga ataagaccta ctgtaagagg ttctgtaatg
     3421 aaccctaatg accatccaca cggtggaggg gaaggtagat ctccaatagg tagaccatct
     3481 cctgttactc catggggtaa accagctctt ggatacaaaa ctagaaagaa aaataaagct
     3541 tcaaataaac taatagtatc aagaagaact aagtagtaaa tttatttttg ctcggaaagg
     3601 aggaatataa atgtcaagat caactaaaaa agggcctttt gtccatgcaa gacttttaaa
     3661 gaagatagaa gctatgaatg ctagtggaaa taaagaagtt ataaaaactt ggtcaagatc
     3721 ttcaactgta tttccacaaa tggtagaaaa cactatagct gttcatgatg gaagaaaaca
     3781 tgttccagta tatataacag aagatatggt tggacataaa ttaggtgagt tcgttcctac
     3841 tagaactttc aaaggacata aggatgacga aaaatctaat aagagaaaat aattaaatta
     3901 tgactaagaa aggaggaata acaatggaag caaaagctac tgctaaatac gtacgtgtat
     3961 caccaagaaa agcaggccaa atatgtgacc ttgttagagg aaagaatgtt gatgaagcat
     4021 tagcaatatt aaagtttact ccaagaggag cagcttcaat aatagctaag gttgtaaaat
     4081 cagctaaagc taacgcagaa aacaatcacg aaatggatac tgaaaaatta tatatagcat
     4141 caatagttgc taatcaagga ccaacaatga agagattcat gcctagagct atgggtcgtg
     4201 caactacaat aagaaaaaga acttctcata tagaggttgt tgttaaagaa aaaaaataat
     4261 taatagatag gagggaaagt aatgggtcaa aaggttaatc cacacggctt aagggtcggt
     4321 gttataaaag attgggactc aagatggttc gctactgata aaaaagagtt cggaaactta
     4381 ttattagaag accataatat acgtaaattc ttaaagaaaa gattatactc agctggagtt
     4441 gctaagatag aaatagaaag atcagctaac aaaataaaaa tggacttaca cgttgctaag
     4501 cctggtgtag ttataggaag agctggtgca ggaatcgaag cattaaaagc tgaattagaa
     4561 aaaatgacaa agaaaactat aatagttaat atagtagaag taagaagtac agataaaaat
     4621 gctcaattag tagctgaaaa tatagcttta gctatagaga gaagggttgc tttcagaaga
     4681 gcaatgaaac aagctataca aagagcaatg aaatctggtg ctaaagggat aaaagtttct
     4741 gcttcaggaa gattaggtgg agctgaaatg gctagaactg aaggttatag tgaaggaaat
     4801 gtgccactac aaactttaag agcagatata gattatggtt tcgctgaagc tgatacaact
     4861 tatggaaaaa tcggtataaa agtttggata tgtaatggtg aagttttacc aactagagac
     4921 ggtgtaaatc caagagaaga aagcagaaag agcgatagaa gagacaacaa gagagataat
     4981 agaagaaacg atagaagagg aaatgacaga agaggaaatg ataacagagg aaactacaga
     5041 ggacaaagac ctcaaggtgg atcaagacct caaagaactg aaaacaaagg aaattaataa
     5101 tagttaggtt caaggaagga ggaaaaatac tcatgttaat gccaaaaaga gtaaagcgtc
     5161 gtagagttca tagaggaagc atggctgggc aagctcataa gggtaataaa gttacttatg
     5221 gtgagtttgg attagtagca ttagaagctt cttggataac ttctaatcaa atagaagctg
     5281 ccagaatcgc gatgactaga tatataaaaa gagggggaaa ggtttggata aaaatattcc
     5341 ctcataaacc agtaacaaga aaaccagcag agactcgtat gggtgcaggg aaaggttctc
     5401 cagaatattg ggtagctgta gttaagccag gaagagttat gtttgaatta gcaggtgttt
     5461 ctgaagataa agcaagagaa gctatgagac ttgctgcaca taaattacca atcaaatgta
     5521 aatttgttaa aaaagaagat ttagaagtaa agggtggtga ataggatgaa agctaaagaa
     5581 ttaagagatt taacaagcga agagctaatg aacaaattaa acgacttcaa aagtgaatta
     5641 tttagcttaa gattccaatt agctactggt caattagaaa atacagctag aataaagttt
     5701 gttaagaagg atatagcaaa agttaaaact gttcttgctg aaagaaagtt atacgaaact
     5761 agagcttaat ttggaaagga ggctttttaa acatggaaag aggaagaaga aaagttagaa
     5821 taggccgtgt tgttagtgat aagatggata aaacaatagt agtagctgtt gaagaattcg
     5881 tacgtcatcc actatataat aaacgtgtta agagaactaa gaaattcaag gctcatgatg
     5941 aaaagaatat atgtaacatc ggagatagag ttaaaataat ggaaactaga ccattatcta
     6001 aagataagag attcagacta gttgaagttg ttgagaaagt taagtagttt ttgaagaagg
     6061 agggattacg atatgataca acaagaatca cgtctaagag ttgctgataa ctcaggagct
     6121 aaagaacttt tatgtatacg tgttctaggc ggaagtaaaa gaagatatgg taacataggc
     6181 gacgttatag ttgctactgt taaaagtgca acacctggtg gagttgtaaa aaaaggtaag
     6241 gttgttaaag ctgttatagt aagaagcaaa caaggcgtaa gacgtaatga cggaagctat
     6301 atatcttttg atgaaaatgc tgctgttata ataaaggacg ataaaactcc agtaggaact
     6361 cgtatattcg ggcctgttgc tagagagtta agagacaatg aattcatgaa aatagtttct
     6421 cttgctccag aagtactata attaaggagg tgcaatagga catgatgcgt gttaaaaaag
     6481 gtgacactgt tgtagttata gcaggtaaag ataaaggtaa aaaaggttca gttttaaagg
     6541 tatatcctaa aactagcaaa gtgttagttg aaggtgtaaa tgtaataact aaacatcaaa
     6601 aaccaagtgc tatgaaccaa caaggtggaa taataaataa agaagcccca atacacatat
     6661 ctaatgtaat gccatttgat cctgaaacag gaaaaggcgt tagagtaaga tatgaagtaa
     6721 aagatgggaa caaagtaaga gtatcagcaa agagcggaaa agaattataa taaatattgc
     6781 ttgaaaggag ggaccttaaa tggcttctag attacaagaa aaatacatga aagaagttgc
     6841 tcctgcttta atggagaaat ttggatacaa aaacgtaatg gagataccta agttaaataa
     6901 aatagttatt aacatgggta taggtgacgc tagagaaaat ccaaaaggat tagaaaaagg
     6961 cgttgaagaa ttagaaatga tatcaggaca aaagcctgtt ataactaaag ctagaaaatc
     7021 tgttgctaac ttcaaattaa gagaaggaat gccaatagga acaaaagtta cattaagagc
     7081 tgacaaaatg ttctacttca tggacaaatt agtttcagtt tctttaccaa gagttagaga
     7141 ctttagagga gttaacccta atgcttttga tggtagagga aattatgctt taggagttaa
     7201 agaacaatta atattccctg aaatagaata tgataaaata gataaagtaa gaggaatgga
     7261 tataatattt gttactacag caaaaactga cgaagaagct cgtgaattat taaaattatt
     7321 aggaatgcca ttttctaagt aagcaaagga gggattcccg tggctagaaa agcgatggtt
     7381 gttaagcaac aaagaaagca aaagtacgct actagagaat acactagatg tactatatgc
     7441 ggaagaccgc attcagtttt gaaaaaattt ggtatatgcc gtatatgctt tagagaatta
     7501 gcttataaag gtcaaatacc tggtgttaga aaagcaagct ggtagaagct tgattagaat
     7561 ggaaggaggg caacaaaatg acaatgacag atccaattgc agatatgctt actcgtataa
     7621 gaaatgctaa tgttgttaag catgaaactg tagatgttcc agcttctaat atgaagaaag
     7681 aattagctag aatcttatta gaagaaggtt tcataagagg ttatgatgtt atagaagatg
     7741 gaaaacaagg tatcataaga atacaattaa agtacggaca agaaggcgaa agagttataa
     7801 caggtcttaa gaaaatatct aagcctggaa tgagagttta cgctgctaac catgagatac
     7861 caaaagtatt aaacggatta ggaatatcag ttatatctac ttcaaaagga atattaactg
     7921 acaagcaagc tagaaaagaa aatgttggtg gagaagtaat ctgctacgtt tggtaattaa
     7981 tatgaacaat gtaaggaggt gcgaccatgt caagaatagg tgttaagcca ataataatac
     8041 cagcaggtgt tgaagttact atagctgaag gaaatttagt tacagtaaaa ggtccaaaag
     8101 gaactttaac taaacaatta agtgctgagt taaacataaa aaaagaagaa aatacaataa
     8161 tggttgaaag accaactgat aataaaaaac atagatcttt acacggacta actagaactt
     8221 tattagataa tatggttgta ggtgtaaata ctggtttcga aaagaaatta gaattaaaag
     8281 gtgttggata tagagctcaa aaacaaggaa agaaattagt tatgaactta ggtttctctc
     8341 atccagttga gatggaagat ccagaaggaa taactgttga agctccaaac caaacagagt
     8401 taatagtaaa aggtatagac aagcaattag tagggaatta tgctgctaag ataagagctt
     8461 ggagaaagcc agagccatac aaaggtaaag gtataaaata cgttgatgaa gtaatcagac
     8521 gtaaagaagg aaaaactggt aaaaaataat accaaaactt aaacgctaga aaggagtgag
     8581 ctaggtgtta aaaaaggctg ataaaaatgc taatagactt caaagacata agagagttcg
     8641 tagaaaaata agcggtactt ctcaaagacc aagattatgt gtatttagaa gtgctaacaa
     8701 tatatatgct caaataatag atgacacaaa aagagtaact ctagttgctg catcttcttt
     8761 agaagcagaa gttaagagtg ctgtcaatca tacaggaaac aaggaagcag ctaagaaagt
     8821 tggagaatta gttgctaaaa aagctgttga aaaaggaatc actgaagttg tatttgacag
     8881 aggtggatac ttatatcatg gaagaattca agaattagct gaaggtgcta gagaagctgg
     8941 tcttaagttc taatacgaag gagggaaaaa tacatgctac gtcgtaagcc gatagatgca
     9001 ggacaacttg acttacaaga aaaagttgtt gaagtaagac gtgttactaa ggttgtaaaa
     9061 ggtggtagaa atttcagatt tgcagcatta gtagttgttg gagatgaaaa cggacacgtt
     9121 ggtataggtg ctgggaaagc aatggaagta ccagacgcta taaaaaaagc agttgaagat
     9181 gctaagaaaa atctaatagt agtgccaata gttgggacta caattcctca cgaagtacgc
     9241 ggacactttg gtgctggaaa tatattaata atgcctgctg tagaaggtac aggagtaata
     9301 gctgggggac ctgctagagc cgtacttgag ctagctggac taaaagacgt tagagctaaa
     9361 tctttagggt ctaacaatcc aagaaatatg gtaaatgcta caatagaagg acttaattct
     9421 ctaaaaacag ttgaagatat agctaaactt agaggtaaaa aagttgaaga acttctaggg
     9481 taaggaggta gtgtaaaatg gctaaattac aaataaagtt agttagaagt gttataggaa
     9541 ctactcctaa ccaaaaaaag aatgttgaag cgttaggatt aagaaaaaga gaacaagttg
     9601 ttgtaaaaga agacaatgct caaacaagag gtatgataaa taaagtaagt cacttattag
     9661 aagtaactga aatagctgaa taatttttat aaagtagtgc aaggaggtgc aatccatgaa
     9721 gttacatgag ttaaaacctg ctgaaggtgc agtaagagct aagagaagat taggtagagg
     9781 tactgcaact ggacaaggta aaactgcagg acgtggacaa aaaggtcaat ggtctcgttc
     9841 tggtggtgga gtaagagtag gatttgaagg tggacaaatg ccactagcta gaagacttcc
     9901 taagagaggt ttcaataaca tatttaagaa agtttacaca gaagttaatg ttgaagtttt
     9961 aaacagattt gaaaatggaa cagaaataac tgcagaatta ttaaaatcta ctaaaactat
    10021 aagcaaaata ggtaaagacg gaattaaaat cttaggtgaa ggtaatttag agaaagcttt
    10081 aactgttaaa gctgctaaat ttacagcttc agctcaagaa aaaatagaaa aagctggtgg
    10141 aaaagcagag ttagtataat aacctgctaa tctcctagcc agtacaggcg gggtgaatta
    10201 gcgtgctgtc aaaattaaaa caagcttgga agattaaagc agtaagaaaa aaagtaatgt
    10261 atacacttat gatgatcgtg atattcagaa taggtactac tataccagtt ccaggcatag
    10321 acactagtat tatacaaaag atggtaggcg gcaatagtct actttctctg tataatatgt
    10381 ttactggtgg agcatttagt aacttttcac tatttgcttt aggtataagt ccatatatca
    10441 ctgcatcaat cataatacaa cttctaacag taggttttga aagtttagca gaacttcaaa
    10501 aatctggtga agaaggaaag aaaaaaatca ataagtacac taaatataca gcactagctc
    10561 tagcagttgt acaagctttg ggaattacat taggaattgt aagaagtgct ttaatatcaa
    10621 atagtgtgtt ttttatcaca actgttgtaa taacattagt ttcagcaagt atgttagtaa
    10681 tgtggattgg ggacaaaatt actgaaaaag gaatcggtaa tggtagttca gtaataatat
    10741 ttgcaggtat aatatcaaga atacctacag atgttattaa aatatcgcaa caagttaaat
    10801 ctggcgaagt tgcaccttgg gttatagtga ttctagctgt agttatatta cttacagtaa
    10861 caggagttac atttatacaa gaagcaacta gaaagatacc tgtacaatat gctaaaagag
    10921 ttgttggaag aaaaatgtat ggaggacaaa gttctcatat accaatgaaa gttaaccagt
    10981 caggagttat gcctataatt tttgctagtt cacttttagc tttccctcaa acaatagcta
    11041 tgtttatggg tccaaatgct caggcttttg ttcaaaaata cttaagtatg gcaacagaac
    11101 aaggattttg gacatataga tcaattgaga ttctacttat aattttcttc tcatattttt
    11161 atacaactgt atcatttaat acagaagaca tatctaaaaa tatgaaaaat aatggtggat
    11221 ttataccagg tataagacca ggtgagccta ctatggatta tttaaataga attttaacta
    11281 gattaacttt agctggagct actttcttag caataattgc tatggtgcca gctcttacaa
    11341 cacattatat gaaagtaaat atgagtctag ctgggacttc attgctaatc gttgttggag
    11401 ttgctttgga gcttaagaga cagttagagt caaacttagt tatgagaagc tatcaaggtt
    11461 tcttaaaata aaatggagat ggataatatg agaataatat tacttggacc tccaggtgct
    11521 ggtaaaggta ctcaggcggc aggaatagta gaaaaataca atatacctca tatatcaaca
    11581 ggagatatat tcagaaagaa tataaaagag ggaacagaac ttggaaaaaa agctaaagaa
    11641 tacatggacc aaggtttatt agtaccagat gagttaactg taggtttagt tactgataga
    11701 atatctcaag aagattgtaa aaatggattt atgttagatg gatttccaag aaatgtagca
    11761 caaggagaac atttagatat cttcttaaaa aatgctggta tatcactaga taaagttgtc
    11821 aatattgaag ttgataagag tatattagtg tctagagcag ttggtagaag aatatgtaag
    11881 tcttgtggag ctacttacca tgttgagttt aatcctccta aagtagaagg tgtatgtgat
    11941 gtatgccaag gagaattata tcaaagagct gatgataatg aagaaactgt atctaagaga
    12001 atacaagttt atctagatga aactaagcct ttagtagatt attatagcaa acaaggtata
    12061 atagcagata taaaaggtga tcaagcaata gataaagtat ttgaagatat tgtcgcagcc
    12121 ttaggaagtg gaaaataaat gattatcttg aaatcaaaaa aagaaataga acttttaaga
    12181 gaagcaggta aaatagttgc tgacactcat gaagttttaa gaaaagctat ttctccggga
    12241 atatctactt tagaattaga taaaatagct gaagagaata taagaaaata caatgcagaa
    12301 ccttctttta aaggatatgg aggttttcca ggaagtatat gtgcttctat caatagagag
    12361 gtagtacatg gtattccagg agaaactata ttacaagaag gtgacattgt aagtttggat
    12421 ataggagcct attataaagg atatcatggt gattctgcga aaactcacgg agtaggcatg
    12481 atatctgaag aagataggaa attgatagaa gtaactagag aaagcttcta tgaaggaata
    12541 aaatttgcta aattaggata tagactttca gatatctcac acgcagtaca aacacacgtt
    12601 gagaaacatg gtttctcggt agttagagat ttagtgggtc atggagttgg agcaaatctt
    12661 catgaagacc cacaagtacc taattatgga ctcccaggaa aaggaccaag acttagagaa
    12721 ggaatggtta ttgctataga gccaatggtt aatgcaggtc gttatcatgt aaagactcta
    12781 tcagatgggt ggacgactgt tacaatagat ggaaaaaaat cagctcatta tgagcatacg
    12841 atagcaatta ctgaacatga acctttgata ttgacaaagt tgtaatttaa aaagtaggtg
    12901 aaaaaagtgc tatcagataa tttaagtata ggtcaagttg ttaaagtttc attaggacga
    12961 gataaaggaa atttattctt tgtagtcaaa ataattaata atgaatatgt attaatagct
    13021 gatggaaaaa agagaaaact tgacaaacct aagttaaaga aagtgaagca cttaaaaaaa
    13081 tataatttta ttaatgatga agttagaaaa agagtagtat ctggacaaga gattacagat
    13141 tcttttttaa gagctgaact tactaagtta aattagataa tttaacttat tgaaatggag
    13201 ggctggttag ttaatggcca aaaaagatgt tatagaatta gaaggtacag tttcagaagc
    13261 tttacctaat gctatgttca aagttaaact agaaaatgga catgagatat tatgccacat
    13321 ttctggaaag ctaagaatga acttcataag aattcttgaa ggtgacaagg tgaatgttga
    13381 actttctcca tatgacctta caagaggaag aattacttgg cgtaagaagt agactatatt
    13441 aatatttagt ctaaggaggg attaataatg aaggttagac catcagtaaa accaatatgt
    13501 gaaaaatgta aagtaataaa aagaaaagga aaagtaatgg ttatctgtga aaatccaaag
    13561 cataagcaaa agcaaggata agaaattatt actagcattt tgttaaattt tatagtataa
    13621 tactatattg tgatgttaac aaaagaacgt taaaatcgtt gaacaatctg gcgtaggatt
    13681 ggcatatgat gtgaagtttt aaacactaaa aactatgtgt aggaggtgcg atcatggcaa
    13741 gaatagctgg ggtagattta cctagagaaa aaagagcgga gataggctta acttatatat
    13801 atggtatagg taaagcaact gctaacgaaa tattagctaa ggctgagata aatccagata
    13861 ctagaataaa agatttatca gaagatcaag ttaatgagtt aagaaaagtt atagatgacg
    13921 atttcttagt tgaaggtgac ttaagaagag aaattgcttt aaacataaag agattaagag
    13981 atataaaatg ttatagagga ataagacacg ctaaaggtct tccattaaga ggacaaagaa
    14041 ctaagactaa tgctagaact agaaaaggtc ctagaaaaac agtatctcgt aaaaagaaaa
    14101 aataaataaa taataactag atgaaggagg gaaaaggaaa atggctaaac caaaaaagaa
    14161 agttacacgt attagaagaa gagaacgtaa aaatatagaa cgtggtcatg ctcatataca
    14221 atcaactttc aataatacaa taataacttt aactgacgtt cacggaaatg ctatatcttg
    14281 ggcaagttct ggacaattag gattcaaagg atcaagaaaa tcaactccat ttgcatctca
    14341 aatggctgct gaaacagctg caaaagctgc gatggaacac ggactaaaaa gtgttgaggt
    14401 attcgtaaag gggccaggtt caggaagaga agctgcaata agagctttac aagcaactgg
    14461 actagaagta actatgataa aagacgttac tccaatccca cataacggat gcagaccacc
    14521 aaagagaaga agagtgtaat taataagagt acaataggag gtgtagataa atggcaagat
    14581 atacaggtgc atcatgtaga caatgccgta gagagggaat gaaattattc cttaaaggtg
    14641 atagatgtta tacagacaaa tgtgctatag taaaaagaaa ctatgctcca ggtcaacatg
    14701 gccaaggaag aaagaaagtt tctaactatg gattacaatt aagagaaaaa caaaaagtta
    14761 aaagaatata tggagtttta gagactcaat ttagaaattt atatgaacgt gctgaaaata
    14821 tgcctggtaa agcaggtgag aacttattaa gtttattaga gagaagatta gataatgtag
    14881 tttacagaat gggactagca tcttctagaa aagaagctag acaattagtg actcatggtc
    14941 atttcacttt aaatggaaat aaagtagaca taccttcatt aatagttaag gttggagatg
    15001 ttatagaagt taaagagaaa tcaagatctt ctgcaaaatt caaaaattta gtagaagtta
    15061 actcaagaat agctcctaag tggttagaag ctaatgtaga aggaatgaca gcaaaagtag
    15121 ttggtgttcc aacaagagaa gatatagatc ttgagatagc agagcactta atcatagaac
    15181 tttactctaa ataataagca cacttttaaa aattatttta aaattttgtt taccctcagt
    15241 ggattactga attttaagga gggttttgtc catgatagaa atagaaaagc caaaagtaga
    15301 tatagttgag cttagcgaag actatagata tggtaagttt gttatagagc ctctagaaag
    15361 aggatatgga ataactatag gtaacgcatt aagaagaata ttattatcat cattaccagg
    15421 tgtagcagtg aatgctataa aaatagatgg agttcttcat gaattttcaa caatacctgg
    15481 tgttaaagaa gatgttactg agataatatt aactttaaaa gagctttcag caactataga
    15541 tggtgaagga agtagaacac ttaaaataga agctcaagga ccatgctcta tcacaggtgc
    15601 agatataatc tgtcctccag atgttgaaat attaagtaaa gatttagcaa tagctacatt
    15661 agatgataat gctaaactta atatggagat atttgtagat aaaggtagag gttatgtttc
    15721 tgctgaagaa aataaaacag agaatgttcc aataggtgtt ttacctgtgg attcaatata
    15781 tactcctgtt gagaaggtta gttatcatgt ggaaaacaca agagttggtc aaaaaacaga
    15841 ttatgataaa ttagtattag aagtttggac taatggtagt ataaatcctc aagagggaat
    15901 atcattagct gcaaaggtat tagttgagca tttaaactta tttatagact taactgaaca
    15961 tgtaagtagt gttgaaatca tggtagaaaa agaagaagat caaaaagaaa aagttcttga
    16021 aatgactata gaagaattag atttatcagt tagatcatat aactgtttaa agagagcggg
    16081 aattaataca gttgaagaat tagctaataa atctgaggat gatatgatga aggttagaaa
    16141 cctaggtaag aagtcattag aagaggtaat acaaaaacta gaagaacttg gattgggatt
    16201 aaaaccaagt gaagaatagc gagcaaagga gggataagaa tggctaagta ccgtaaatta
    16261 ggacgtgaaa cagctcacag aaaccttatg ttaagaaact tagtaacttg cttactaaga
    16321 agtggaagaa tagaaactac agtgactaga gcgaaagaaa ctcgtagaat ggctgaaaag
    16381 atgataactc ttgctaagag aggagatctt catgctagaa gacaagtttt agcttatgtt
    16441 atggatgaaa cagtagttaa taacttattc acagatttag ctccaaaata tgctgagaga
    16501 aatggtggat acactagaat aataaaaata gggccaagaa aaggcgatgc tgctgaaatg
    16561 gcttttatag aattagtata gtaaggaaag gattaggctt gatggcttaa tctttttttt
    16621 atttttttga ctaaggtatg atataataat gtgtaaaatg atttttataa gttattgctt
    16681 actaaaagga gtatgagtta atggataata tagtaaaggt aaataatatt tcgtttgagt
    16741 atattacaga tgaagcaaaa cttaaagcaa tagataattt aagcctagat gttaaaaaag
    16801 gagaatttgt tgcgataata ggacataatg gttctggtaa gtctacttta tctaaaaact
    16861 taaatgctat tcttatgcct actgaaggaa atattcttat tgatgatatg gatactaaag
    16921 aagaagaaag attatgggat ataagacaaa ctgcaggcat ggtatttcaa aatccagata
    16981 atcaaatagt tgctactata gtagaagaag acgttgcatt tggacctgag aacttaggta
    17041 tagaaccaaa agaaataaga cgaattgtag aggagtcttt aaaaagtgta ggtatgtatg
    17101 atttaagaga tagacagcct catttgttat caggaggtca aaagcaaaga gttgcaatag
    17161 caggaattat tgctatgagg cctaaatgta taatatttga tgaagcaaca gcaatgttag
    17221 atccatctgg aagaaaagaa gttatgaaaa caataaaaag acttaataag gaagaaaata
    17281 taactgttat acatataacg cactttatgg aagaagcagt agaagctgat agagttgtag
    17341 ttatggaaaa aggaaagaaa atcttagagg gaactcctag agaagtattc agtaaaataa
    17401 agatgttaaa ggaaatcggt ttagatgtac cttgtatgac agagttatct agtttattaa
    17461 tagaagaagg tataaatatt agtagtgata tattaactgt ggatgagatg gtgatggaat
    17521 tatgtcaatt atagtaaaga atttaacaca tatatataat gaagggatgc cttttgcaag
    17581 taaggcactt gatgatgttt cttttgagat taaagataga gattttgttg gtcttatagg
    17641 tcatacaggc tcaggaaaat ctacattaat acaacattta aatggattac taaagccttc
    17701 ctcaggagaa atatttataa atgattttaa tataacagat aaaaacttga atttaactga
    17761 gattagaaaa agagtagggg ttgtatttca atatccagaa taccaattgt ttgaagaaac
    17821 gattgataaa gatatagctt ttggaccctc taatttaggc ttagaggagt ctgagataca
    17881 taacagggta aaagcatcaa tggaagctgt aggacttgat tatgagggat ttaaagacaa
    17941 atctcctttt gaattatctg ggggacaaaa gcgtagagta gcaattgctg gagttatagc
    18001 catgaaccca gaagttctca tattggatga accaactgct ggtcttgacc ctggtggaag
    18061 agatgaaatt tttaacttaa taaaagactt acatgaaaaa aagaatatga ctataatact
    18121 atcatcacat agtatggatg atatggcaaa gttagcaaaa actttaattg ttatgaatca
    18181 tggtagcgta gaatttatgg gaactcctag agaagtgttt aaatcaaatg ctagtaaatt
    18241 aaaagatata ggattagata ttccacaagt tttagaactt gcattgaaat tgagagaaaa
    18301 aggctttgac atcagtgagg atatattgac tttagaagaa gcaaaacagg aaatattaaa
    18361 agttgtgaga ggacgaggat tatgttaaaa gatataacta tagggcaata ctacccaaca
    18421 agttctgcta ttcataaatt agatccaagg ataaagcttg tagcgacaat tgtatttatg
    18481 gtatctatat ttgtagtaaa taaattttgg ccttatatag tagttttatt atgtttatta
    18541 gctatgataa aattggctaa tataccagtc aaatatattg ttaagggtgt taaacctctt
    18601 aaatggatta ttttgtttac atttcttata aatatttttt tcttaccagg tgatgaaata
    18661 tggtcatttg gatttttagc tattacaaaa cagggtctaa gacaagcaat ttttatggca
    18721 ataagattaa tatttttagt agttggtaca tcattgctta ctttaacaac ttcaccaata
    18781 gaattaactg atggaataga gagattgttg aatccattta agaaaattgg tttgccagtt
    18841 catgaacttg caatgatgat gacaattgct ttacgtttta ttcctacatt gttagatgag
    18901 acagacaaaa taatgaaggc tcagatgtct agaggtgcag attttgaaag taagaatctt
    18961 ataaatagag caaagaattt agtaccactt ttggtacctt tatttgtaag tgcatttaga
    19021 agagctgatg aattggctat ggccatggag gccagatgtt acagaggtgg acataatagg
    19081 actaagatga gagagtctgt tatatcaaga agggattata tggcatgtgt atttcaggtt
    19141 gtttatctgg gagcaattat agctactaga tttatagcaa tttaattaat aagttataga
    19201 tataatgagg taaagtatga gaaatataaa aattaaaatc caatacaatg gtaagaatta
    19261 ttgtggatgg caaaagcaac ctgattcttt agggatacaa ggtacaattg aaagggctat
    19321 atatgatata acaaaagaag aaaccagtct tatagggtct ggtagaactg attcaggagt
    19381 tcatgctatt ggtcagattg caaattttaa aattaattca ggtataagta tagaaagtat
    19441 accaatggca ctaaatgcca agttgccaaa agacatatca gttatagaag catgtgaagt
    19501 aaatgatgat tttcactcca gatacagtgc aaaaggtaaa acatataaat atttagtata
    19561 taatagcaag tttagaaatc caatacttag tgagatatca tatcaagtaa aatatgaact
    19621 tgattttgat aaaatgtgtt cagaagcaaa aagtttatta ggaacacatg attttaaagg
    19681 ttttatgagt tctggttcat ctgtaaaaga tacagttaga acgatatatg atattgatat
    19741 aagtaaaaaa gatgacttga ttacttttga gattagtggt aatggttttt tatataacat
    19801 ggtgaggatt attgttggaa cacttgttga tatgggtcgt ggcagaatta acgaaccatt
    19861 tttagatata atacaatcaa aaactaggtc aagatgtgga catacagctc cagcacaagg
    19921 attatttctc aaaaaagttc attattaact tgacacacca ggctacatgt attaaaatat
    19981 atgagaatgt gttaataagt ccacttgccc cggacttgac ataaacggta aaaaaatttt
    20041 atgaaaagta gttaaggagg gacagttatg aaaagttata tagctaagcc agctgatgta
    20101 caaagaaaat ggtacttagt tgatgctgaa ggaaaaacat taggtcgttt agcaacagaa
    20161 attgcgacag tattgagagg taaacataaa ccaacattta ctcctcacgt tgatggtgga
    20221 gattttgttg ttgtagtaaa tgcagaaaaa atagttttaa gtggtaagaa attagatcaa
    20281 aaatattaca gataccatac tggttatgta ggtggattaa aagaaatatc ttacagagat
    20341 atgatggata agaaaccaga agaagttata tcacatgctg taagcggtat gttacctaaa
    20401 aataaattaa gaagcagaat gatgactaga ttaagagtat ttgcaggtgc tgagcacact
    20461 catgcagctc aaaatccaga agttttaaac tttaaataag attaataggt gaaaggagga
    20521 gtttataatg gctaacgttc aatattatgg aactggaaga agaaaaagtt ctgttgctag
    20581 agtaagacta gttgcaggtg aaggaaatat attagtaaat ggaagagcat tagaaaatta
    20641 ttttaattat gagacattaa taagagatgt taaacaacca ttagttttaa ctggtaatga
    20701 aaataaatat gatgttatag taaaagttga aggtggagga ttcactggac aagctggagc
    20761 tataagacat ggaatatcta gagctttatt aaaagctgat ttagatttaa gacctgcttt
    20821 aaagaaagaa ggtttcttaa ctagagatgc aagaatgaag gaaagaaaga aatacggatt
    20881 aaaagcagca agaagagctc cacaattctc aaaaagataa ttacttattt ttttggaaaa
    20941 gcaaaatcct ttatttactg ttattcagaa agtattggta ttttaaaaat gttgggttaa
    21001 gttaattatt gatatataat aaaataataa gatatcttat taggatgttt ttcattaaga
    21061 agaacatcct ttttattttg actatttaat aaaaaacata tgctaataag atttaaattt
    21121 tatttttata atattgtaat ttaaaagttt atataaggtt atatatttta agatattatt
    21181 taacaatata aattctgaat atacgttatc aaagtttata atataaacta agtataattt
    21241 attgtatagt attgaatgtt agataaacat agtgaattaa ataggggcag aaatataata
    21301 tcattacata ataatatatt aataccaata aataaagata tatcaatatt aaaaaaattt
    21361 aaatgtttgt actaatatat ggaatattat agtgttttta taagtataca tatacagggt
    21421 gatgttgtga gaaagtacat aaaacatata atttttagtt ttgcaatgat atgtctagta
    21481 gtagtatcca tatttgaaat taaaaatatt tctgaagatg ttatcaagta tatgccagta
    21541 acaaacaaaa ctataatttt agatgctggt catggaggca ttgatccagg tgcattaaat
    21601 aaggataaga gtacatctga aaaggatatt aacctagcaa taacacttaa gcttagagag
    21661 cttatagaat caagtggtgg ccttgtaata ttaactcgag aagatgacag tagcctttat
    21721 aaagaagaaa ataataaaac tacaagacaa aaatataatg agaatttgaa aaatagaaaa
    21781 gaaataatat ctaattctaa tgccaatatg tttgtctcta tacatcttaa tgcatttgaa
    21841 caatcaaaat actatggagc tcaaactttt tatcctaaag acaaacaaga cagtaaagaa
    21901 ttatcgaagt gtattcaaga agaacttaaa agagtagtag ataagacaaa caacagagaa
    21961 gtcaaaccaa gggatgatat atatcttttg aaagaaaata atattccatc agtactgata
    22021 gaatgtggtt ttttatcaaa tgaaaaagag tgtaaactct taactgatga aacatatcaa
    22081 gaaaaaatag catgggcaat ctacatagga atacaaaaat atttaagttg aaataactat
    22141 aaaaataggt ctaaatatgt aaatagcttg tattaaagca gttaaaatgc attaatatag
    22201 gctattttta ttttgacaaa aaaatattta aaataaaagt taaaaagttg ttgacttaga
    22261 ataatataga tgatattata tatgagtgcc caaaaggagc accaaaataa gacaaa
//
LOCUS       DAEPKC010000064        21913 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.064, whole genome shotgun sequence.
ACCESSION   DAEPKC010000064 DAEPKC010000000
VERSION     DAEPKC010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21913)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21913)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21913
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.064"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            161..943
                     /locus_tag="KR294_002474"
     CDS             161..943
                     /locus_tag="KR294_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBH0240544.1"
                     /translation="MMILPLSSVSIAKFYTEGRNNDKYNFYSSVILFFIIYFFIFIIE
                     SLKLISINQFQLMYLMLILISSLCVIVYSYKITSLYIFKNFKIGILLFFYFLFSQIIF
                     GLIISDNQFDYKNFLNYILLPIISLVYIYPFLCEEYGWRSFLQSILFDRFGKKIGIVM
                     VGTCWSLWHLPLQFTLYSPQTPIIGAIANLIYGIGLSIFLGYVYMKTKNIWFCSIMHV
                     LINSLGLIFNDSEIIINYHSIIQRLIFILLFYTPFLFTKEYK"
     gene            1323..2849
                     /locus_tag="KR294_002475"
     CDS             1323..2849
                     /locus_tag="KR294_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBH0240545.1"
                     /translation="MNESYWFLNSSPKEYNKLGENIKTDCLIVGGGITGLTTAYLLAK
                     EGKKVVLVEADKIGYGTSGRNTGKVTCQHDIFYSKIEKKYGLDKAKSYYNANNEALNL
                     VEQIIEENNIKCDFKRETSFVFTEKEDTIKDIKDEYRTCKKIGINCEYHETIENIPLD
                     IKGAISFTNQGQFNPKKYIDGLAKAAVNLGLKIYENTPVVDLEKGKICRVKTREDNII
                     EAENVIISSHSPWYDGLNFYFAKEYAERAYLMVAVLENKLADGMFISIDDPSITFRQY
                     NDGSENLLIFGGGDHKVGQGGTEKEIFDDLEHYGKEVFKVKDFKGKWSAQDNMSFDNV
                     PYIGYINKREDNIYVATGFSKWGITNGTAAGIIIKDLIINNNSDYKDTFNPSRLGSYF
                     SKDFIKENANVAINYVSGKLKIGSGDMPKNNGEGKIVNIDGKRYGVYKDDNGDFYIVD
                     TTCTHLGCELNFNSEEKTWDCPCHGSRFDYKGNILEGPALKPLKLYGHGDNDVNPKLL
                     "
     gene            2877..3434
                     /locus_tag="KR294_002476"
     CDS             2877..3434
                     /locus_tag="KR294_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240546.1"
                     /translation="MNKLLKPITILLYIVYILSAVFFVANKEYGSLGLVAISLVGTFI
                     LSFINKQTERLLSKELYIMLALFIMFSSLLGTCFNFYDINYYDDFLHLWSGIISCIVA
                     FSIIKYFYTQREISKMSKVFLVIFLFMFSMGVASLWEIGEFLMDTFVGTTTQAGGLED
                     TMIDMVDALIGTIITIPFIVKKSNI"
     gene            3956..4999
                     /locus_tag="KR294_002477"
     CDS             3956..4999
                     /locus_tag="KR294_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240547.1"
                     /translation="MLKKWFGIVKKRQKSESAKEEGEVILKNEKILSEEKLIDEEGVV
                     VNIDNEILTKVEVVNDDNEIEEKIIEEDWLISENTIKLDDKEAIINDKNIELCKKEVQ
                     VESEKIGLNKFEGLDQNENYNLEKNVIEEKKVSECLTEEDLEYIKEIKIKRGKSIKAI
                     NLYTKEEWVFDTHIQCSKKLKVPLGYIRENLKYGYMDYFGDAINYLSEVLNIDEYCKS
                     EWSYLDNSKSPSEIFNILNNKIFSIRLSNEKRNEILTNDKIEALKMNYRFECIDEEYD
                     EYFKKYKSIIKRGGKKKVELVNKKGDILEIFKSLEECAIYLQKEKNEVIQMLKYGDTK
                     VGRNFIRYSLRSI"
     gene            5110..6252
                     /locus_tag="KR294_002478"
     CDS             5110..6252
                     /locus_tag="KR294_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBH0240548.1"
                     /translation="MSEEKNPKENTLDESKNSDNVNSKKDDVSDEKNTDNKVKKREIK
                     LNNKTLKAIVAIVAVGAICLGGGYVFGKEAGRKLPATSKHYNSSEVVATIGDKKITGE
                     MLRKRMEPLFYLNAKTTMTDDEIRSYESNMIETMITSDILSSEAAKEKISITNDQLDA
                     QYNNLMSSIESAMGMTKEEFLKQFDLTEKYIKDDMKKELVASKYLNEKSKVTDKEAEN
                     YYNKNKSNYLQVRASHILIKTVDDKGKQVSSSKKAELKKEAEEILKKAQAGEDFATLA
                     KKYSEDSSAESGGDLGFFGKGQMVESFEKAAFALKKGEVSNKLVESDYGYHIIKKTDE
                     KYQPFEEVKSDLVSSLTSEKQNLLIQNLKEKYNVKITDKYQMKAKE"
     gene            6706..8097
                     /locus_tag="KR294_002479"
     CDS             6706..8097
                     /locus_tag="KR294_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HBH0240549.1"
                     /translation="MSSTESVSKKSGHPKSFWLICMTILWERFSYYGLTALLVLFFTA
                     SVAQGGLGLSTQEATSMFGLFTGLIYLTPLVGGWLADKVLGQQKCISIGALLIAIGDF
                     VLFASSTSIAMVWVGLSIIILGNGFFKSSCSNIVGDIYPKTDVSRKDAAYSLFYMAVN
                     VGAFIAPIICGLLSDNVFAVRGASGDIVSYGYKMAFLICGIGMMLGMIIFTLLAPKLL
                     NEVGKYPVTKGNKGEKIEYGPLTKLEKNRIIAMVILFLFVVLFWTAYYQTQSSFMIYV
                     RDNVNRTLFGFEMPVAWLTSLNAILCVALCPVLATLWVKLSHTKRGDFSIPVKMGLGM
                     IIMGVGFIVMVFATLANGPDGMVKASILFIVLTYIFTTVGELFLSPIGLAMFNKLAPA
                     KYATLSMGAWYLTSFFASLLSGKIAGFTATLGFLQIFGGIATVLIIFGLILLGIRNVL
                     TRLMAMDLLTKEK"
     gene            8350..10143
                     /locus_tag="KR294_002480"
     CDS             8350..10143
                     /locus_tag="KR294_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBH0240550.1"
                     /translation="MNIKDRLSGLRKFMEEKNIDAYMIPSSDNHQSEYVGDYFKSREF
                     ISGFNGSAGTVIVTKDEAGLWTDGRYFIQAESQLEGSTIKLFKMGQEGCPTTDEYLYK
                     NIPEGGTLGFDGRVISAREGATLAEKLSKKGIKIEYQYDLIDSIWPDRPALSDSKAFL
                     LDVKYCGESFSSKLARLREKMSEKGTSTHVITTLDDIAWLFNIRGGDVKYNPVVLSYA
                     VITLKEVYLFVDESKLNEEILNELAKENVQIKPYNDVYEFVKNIDKTEKVLLDGTKLS
                     YTIYNNIPCEVEKVDEFNPVMFFKAQKNEVELENIRNSHVKDGVAFTKFMYWLKKNVG
                     KMEITEISATQKLEDLRREQEGFFEPSFNTIAAYKEHAAMMHYSATPESNYKLEAEGL
                     FLVDSGGQYYDGTTDITRTTVLGPISDELKLHFTSVARGMINLSKAKFLHGCRGYNLD
                     ILSRSCMWNMGIDYQCGTGHGIGFVLNVHEAPNGFRWRVVPERFDSAVLEEGMVTTNE
                     PGIYIEGSHGIRTENEIVVRKAEKNFYGQFMEFEVVTLAPIDLDGIVPELMNKDEKDY
                     LNWYHKLVYDKISPFLTDEEREWLKVYTRAI"
     gene            complement(10224..11606)
                     /locus_tag="KR294_002481"
     CDS             complement(10224..11606)
                     /locus_tag="KR294_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HBH0240551.1"
                     /translation="MSVLKTQEKLKQPRDLYFCCSIFTFVGLAYYGMKLVLLLFLAEQ
                     VSKGGLGLTPAESASMLASFLAWTYFSPVIGGWVSDRFLGPKNCIILGMLMVSIGYFL
                     GYIANSKMDINIMIFLSGLGIGFYKGNLHTMVGNLYTNDDPRKDGAFSITYMATNLGT
                     LFGPLICGLVANEWFAMKSGLSISMYGYRYVFLFSSITVLIGLFFFIFGNRKFYKPLN
                     NDPSNGRESIRKSLEYKKMLASRPLTLIEKKRIIVILVLAFFTVFFWIAYNQASMSIA
                     LYTKEHINLTVGNFQIPTSWIDSYNGLLCVILGPISALVWVKLSQTKKGDLSVPKKMS
                     LGFILLAIAFLFMIVAVIQTGTDPNSIHKASVFWVVGFLTFQSIGEICFSPVGYGMVN
                     KLSPEKYISFLMGVWFLGKFAANKLSGYTQAIIDQLGMLQVFIVIPSFLLIFGIILLI
                     MNKKLVELSN"
     gene            11864..12211
                     /locus_tag="KR294_002482"
     CDS             11864..12211
                     /locus_tag="KR294_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HBH0240552.1"
                     /translation="MIRKKSELQVEVKENLNGGIGKVKLENIIQNEELKGKGRLFKRV
                     ALPVGSSIGVHDHTTDFEVYYILKGKGKVFDNGEFVEVNEGDVVYTADGEKHSIENIG
                     EEDLEFVALVLYM"
     gene            12229..13263
                     /locus_tag="KR294_002483"
     CDS             12229..13263
                     /locus_tag="KR294_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240553.1"
                     /translation="MTGKIEEIKDKINRFCNSNLNQEYKDISFKILQNLLDNNKEIIH
                     SSRADIWSSAILNIVLEQNLLYNKKHPLHITKKEFSKQIGVSLNTINNKSSLIKDVCS
                     IDFLNQDTIAISNVEFWVKETNSKSKSVDLDLEKKKILYKRYIKLSQDANSDIESIRY
                     MEEAVNIGKSMITKEDKELGFWKGLSTRAYMIALESLARKLESINNLKESKKVLEYLI
                     EINPSDEQGIRYKLLNVLIRLNDRTSINKLFELYKEEKSATWMYSKALYYFKNKSMFL
                     ANDSIKVARSKNKYVGLYLLDWRNAFGREFVTEEEKAEAVYYYDENIVIWNEVKGSMD
                     WLLKKMLEFS"
     gene            complement(13312..14361)
                     /locus_tag="KR294_002484"
     CDS             complement(13312..14361)
                     /locus_tag="KR294_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH0240554.1"
                     /translation="MEINYKKRNFKSFAKRKNIEISVQRYLIDALSYMALGLFSSLLI
                     GTIFNTLGDNFNISLFTEVISPLAKQVTGPAIAVAIAYGLQAPPLVLFSCALVGACGN
                     ELGGPVGAFVATLFAVEVGKLVSKETKIDILVTPAVTILIGVLVAELIGPAVSAFMTS
                     FGNIIMQATTMQPIIMGALVSALVGIALTLPISSAAICMMLSLGGLAGGAATVGCCCQ
                     MVGFAVMSFRENGVGGLVAQGLGTSMLQVPNIIKNWKIWIPPTVASILLGPLSTTIFK
                     MENIPIGSGMGTCGLVGQFGTVTAMQSAGKGGISMWVGILLLNFILPAIVTLLISEFM
                     RKKGLIKPEDLKLDV"
     gene            14636..16171
                     /locus_tag="KR294_002485"
     CDS             14636..16171
                     /locus_tag="KR294_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240555.1"
                     /translation="MIFVKNKKYRKIAIIISIPILLVAQYYLFKFGILRPMVKGVEIE
                     IVDGEYVKDIDKYVVKLNETVTLSTGEYIKVPSYAKNPNIWFNVLDNSGTLKIDGNKM
                     TALKVGYSSVGIMKNSRVLKKATIKVVDPEVESLDMEINGDLKHVGDSATIESTIEVD
                     YDKFKKSYKPVYKSSNENILKIKGNKVSAVGVGKATIYAKCGNKEIERTFRIQARVAE
                     INMDDIKIEVDQNEKLKPDIITSPPGLEPPKIYYELVDSKLPVERAISLSSNGNVVGL
                     REGKDRVRITCGDKSKVITVTVVKETITNDYIQNLVGSHKIVNNKVIIKLEWDYMKDV
                     FDYDIYLKDKLSGESFKKIKSITINESDLGKSNKVYATIEVDMKGNQNIDFDIYVIGK
                     KDSDTTKPSNVINITNGNGNSNNDNNIKDMRVENISANVDRDNNVIRVNWSSISHKDC
                     TYSIYVKNNTNGDGEFTLYQSDIQGNEHTISIPEGDLNLDIYVVANYNGNSSQNSDVI
                     NVR"
     gene            complement(16356..17042)
                     /locus_tag="KR294_002486"
     CDS             complement(16356..17042)
                     /locus_tag="KR294_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate/glutamate racemase family protein"
                     /protein_id="HBH0240556.1"
                     /translation="MKTIGLIGGMSWESTITYYQVINTVIKERLGGLHSSKCILYSVD
                     FQEIEECQSSGNWEKSAKILADAAIKLQEAGADFIVICTNTMHKVSDKIQESIHIPLL
                     HIADVTATVLREKEIKKVALLGTKYTMEQDFYKNVIINNGIEVLIPNEEDRIIVNDTI
                     FNELCLGIISESSKKAFLSIIDKLGKQGAEAVILGCTEIGLLIKQNDTSIPLFDTTVI
                     HAIEAALSSI"
     gene            17167..18549
                     /locus_tag="KR294_002487"
     CDS             17167..18549
                     /locus_tag="KR294_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBH0240557.1"
                     /translation="MPINSFENYPMTWKPKLDNRKPPIYKTLAMLLEEDIKRGNLNPG
                     DKLPPQRELADFLDLNLSTITRAFKLCEEKGLICAKVGKGTFISSDVNVSNTLLYQTE
                     SKDIIELGTVHPPYEQNTYIIDFIKNVLKQPEMDRFLQYMSPSGTYMQKKSIAKWIER
                     NNVYTSEENILLSTGGQNAICATLLGLFKAGDRIATDSLSFSGIKSIAKMIGIQLVPI
                     PQENNEISIEYLESYCKNENIKGIYLIPDYHNPTTHTMSDLSRKKIAKIAKQYNIIII
                     EDAINSIFRDGIQTPIFSLASDNTIYIFSTSKFLCAGLRVAFVVAPKRYIENLENALY
                     NMNLMVSPFTAEIVHRLLYSPIIDKIIEEKRDAIIERNEVADKVLSDYNLIGDKNCSF
                     RWLLLPDELDGKSFEISAKNLGVQVYCAERFSVGNSTVPKAVRICVTAPKDVEELEKG
                     LNIIKSLLKS"
     gene            18951..20219
                     /gene="eam"
                     /locus_tag="KR294_002488"
     CDS             18951..20219
                     /gene="eam"
                     /locus_tag="KR294_002488"
                     /EC_number="5.4.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 2,3-aminomutase"
                     /protein_id="HBH0240558.1"
                     /translation="MNEQTRISLERAAELKSKIDDYIQARKTINRGLEKEEEINKRKQ
                     KILSILNGTEEDWNNYKWQLSNRITDVDTLSKIITLTKKEKEYIKEVGTQFRWAISPY
                     YLSLIDPEDICDPIKLLSIPTHIELEDEQEDLDPMGEEYTNPAGCITRRYPDRLIINV
                     TNECAMYCRHCQRRRNIGQQDSHKSKAIIQESIDYIRENEEIRDVLVTGGDALTLKDD
                     YLEWILSQLKEIPHVDYVRLGTRTLVTMPQRITDEFCNMLKKYHPVYINTHFNHPMEI
                     TKESKEACEKLANAGVPLGNQAVLLNGINNDKFVMRCLNQELLKIRVKPYYIFQSKHV
                     KGTKHFNTSVDDGLEIMEYLRGYTSGMAIPTYIVNAPKGGGKTPLLPQYLVSKGTDYV
                     MLRTWEGKVIKMEDEPAVDIKKLIKEQAQD"
     gene            complement(20312..20668)
                     /locus_tag="KR294_002489"
     CDS             complement(20312..20668)
                     /locus_tag="KR294_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240559.1"
                     /translation="MKKALISLLVLSCLLLTAPVNESSYADSQKNVPVSQNTKLTQEQ
                     AKELLVKYNNEVDYIYQGNASDFEALKAKNLNGYVFLPDADGDIGYFVNENTSEIYYF
                     HPSGYLELVNQQQNNK"
     gene            complement(20819..21913)
                     /locus_tag="KR294_002490"
     CDS             complement(20819..21913)
                     /locus_tag="KR294_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBH0240560.1"
                     /translation="MQDKKIYLNIVLTVVVSYILIKVIDNYKYFFGVISLLMSLLTPF
                     IIAFVLAYIFNPLVKFLESKLNFKRIYSLLLTYGVLIVILISFILFTVPSIVNSLADL
                     VAQIPTYIDKTEQFLFDLGKSLQSVDPNTLKEYGDKIMSVMPKFSNLLIGSLGGIFST
                     TFSVGKFIVQFLLGFIICFYILLEKEKFLLFTKKVVYISLGKKYGDFIIELCQSLNLN
                     IGKYFTGKILDSFIVGVLSGIGLYFLKSEYALLFGTLMGVMNMVPYFGPVIGMAPVVI
                     INLFSNPTIALTSLIYLIIIQQVEVTFIEPKIVGGQLGLSPFFTILAVTVGGGFFGIP
                     GMILSAPVMGVIKIYFCEFVNRRHDKIQME"
BASE COUNT         8655 a         2453 c         3562 g         7243 t
ORIGIN      
        1 ggtaaacttt ttaaagccaa catatgtcag tgatgaaata aaaagaaaaa aactacaagt
       61 tataatattt ttttctataa cttatggttt atcttattca ctaggtttat tagcaatatg
      121 ttttaatcat ttaatagatt cagaaatttt agctcaattt atgatgatat tgccattatc
      181 ttcagtttct attgcaaaat tttacacaga gggaagaaat aatgataaat ataatttcta
      241 ttcatcagta atattatttt ttattattta cttttttata tttattattg aatcattaaa
      301 gttaataagt attaatcaat ttcaattaat gtatcttatg ttaattttaa taagtagttt
      361 atgtgttatt gtttattctt ataaaataac aagtttatat atttttaaaa attttaagat
      421 aggtattttg ctattttttt actttttgtt ttctcaaatt atttttggat taataataag
      481 tgataatcaa tttgattata agaatttctt gaattatatt cttcttccta taatatcatt
      541 agtatacatt tatccttttt tatgtgaaga gtatggttgg agatcttttt tgcaaagtat
      601 tttatttgat agatttggca aaaaaatagg gattgtaatg gtaggcactt gttggagttt
      661 atggcactta cctttacaat ttacactata tagtcctcaa actccaataa ttggagctat
      721 agccaatttg atatatggta ttggactttc tatattttta ggttatgttt atatgaaaac
      781 taagaacata tggttttgct ctataatgca tgttctaatt aatagcttag gattaatttt
      841 taatgattct gaaataatta ttaattacca tagtattata caaagattga tatttatact
      901 attattttat actccttttc tatttacaaa agaatataag taagaattac aattaattta
      961 tataaaataa atttttaagt aaatattttt atagagagat tgttatatta catatcagaa
     1021 aaatattaaa ctaactaaat caataaaaaa gttggtggat aacaatttat aattgttagc
     1081 acaacatcat cttatgtatt gaaatctaaa atatcctcat ttttacttag cataaatact
     1141 attaattaag aaaataatat agaaattata aatatatata agtttagtct ggtgtataaa
     1201 acaagaaaac taagtgattt ttaatttaac tttttattaa gcttattttt tatactattt
     1261 ataataaata aactccatga tgggaaaact attactattt aatatgtaaa ggagtatttt
     1321 aaatgaatga atcatattgg tttttaaact caagtccaaa agaatataac aaattaggtg
     1381 aaaatataaa aacagattgt cttatagtag gtggtggaat aactggattg acaactgcat
     1441 atttattagc aaaagaaggt aaaaaagtag tgcttgttga ggctgataaa ataggatatg
     1501 gaacttctgg aaggaatact ggtaaggtaa cttgtcagca tgatatattt tactctaaga
     1561 tagagaaaaa atatggatta gataaagcaa aatcatatta taatgcaaat aatgaagctt
     1621 taaatttagt tgaacaaata atagaagaaa acaatataaa atgtgatttt aaaagggaaa
     1681 cttcttttgt atttacagaa aaagaggata ctataaagga tattaaagat gaatatcgta
     1741 catgtaaaaa aataggaata aattgtgagt atcatgaaac tatagaaaat attccattag
     1801 atataaaggg ggctattagt tttactaatc aaggtcaatt taacccaaag aagtatattg
     1861 atggattggc aaaagcagca gtaaatttag ggctaaaaat atatgaaaat acaccagtag
     1921 tagaccttga aaaaggaaaa atatgtaggg ttaaaacaag agaggataat ataatagaag
     1981 ctgagaatgt tataatttca tctcatagtc catggtatga tggattgaat ttttattttg
     2041 caaaagaata tgcagagcgt gcttatttaa tggttgcagt tttggaaaat aaattagcag
     2101 atggtatgtt tataagtata gatgacccat caataacttt tagacaatat aatgatggaa
     2161 gtgaaaattt actgattttt ggaggaggag accataaagt tggtcaggga ggaactgaga
     2221 aagaaatatt tgatgattta gagcattatg gtaaagaagt ctttaaggta aaagatttta
     2281 aggggaaatg gtctgctcaa gacaatatga gttttgacaa tgttccttat attggttata
     2341 tcaacaaaag agaagacaat atttatgtag ctacagggtt ctctaaatgg ggaattacta
     2401 atggaactgc tgctggaata ataataaaag atttgataat aaataataat tctgattata
     2461 aagatacttt taatccatcc agattaggta gctacttttc aaaagatttt ataaaggaaa
     2521 atgcaaacgt agcaataaat tatgtaagtg gaaaattaaa aataggtagt ggagatatgc
     2581 ctaaaaataa tggagaagga aagattgtta atattgatgg aaaaagatat ggtgtatata
     2641 aggatgataa tggagatttt tatattgtag acactacatg tactcattta ggatgtgaac
     2701 ttaatttcaa cagtgaagaa aaaacatggg actgtccatg tcatggttct agatttgact
     2761 ataagggaaa tatacttgaa ggaccagctc ttaagccatt aaaactttat ggacatggtg
     2821 ataatgatgt taatcctaag ttattataaa attattttta ggaaggtaaa gtgtatatga
     2881 ataaactttt aaagccaata actatactat tgtatatagt ttatatttta tctgccgtat
     2941 tttttgtagc aaacaaagaa tatggaagtc taggtctggt agcaattagt ttagttggta
     3001 ctttcatttt gagttttata aataagcaaa cggaaagatt attgagtaaa gaattatata
     3061 taatgcttgc tttatttata atgttttcat cattgttagg tacttgtttt aatttttatg
     3121 atataaatta ttatgatgat tttttgcatt tatggtcagg tataatatct tgtattgtgg
     3181 ctttttctat aattaaatac ttttatacac aaagagagat aagtaaaatg agtaaagtgt
     3241 ttttagttat atttttattt atgtttagta tgggagtagc gagtttatgg gaaataggtg
     3301 aatttttaat ggatactttt gttgggacta ctacacaggc cggagggtta gaagatacta
     3361 tgattgatat ggtagatgct ttaataggca caattataac tattcctttt atagtaaaaa
     3421 aatctaatat atagttttaa attttttata ttaattataa tggatttaat taatcatgtt
     3481 gagtttcaag gtctatatga ttaattaaat ccatttttgt tatttataat tattattgaa
     3541 tatattttta catataagat ataaggtgat agatagaaat tgttggatta tgtaaataat
     3601 taatatataa taccattatg ggcaataaat acaaatcaaa tgataatata gtctatttat
     3661 gtaaatgtta tattgtatac taagtataat agtaagtttt ttgatagtgg tgtagaaagt
     3721 aaaaatctac tagcctaaat tgatgtatgg attagtttag gaacagtaat tgcatatctt
     3781 aagtttgatg tcatgttggg ctactagaaa taggtcatct ttttcacttg aatatctttt
     3841 ctttaaacat ggagagtatc atatcaaaaa catatgaaaa ttaagtgatt tataagaaca
     3901 gtaatatttt atatgatagt atagaatagt aataaagtat taggaggaac attgagtgtt
     3961 aaaaaagtgg tttggtattg tgaaaaaaag acaaaaaagt gagtcagcaa aagaagaagg
     4021 tgaagtaata ttaaaaaacg aaaaaatatt atctgaagaa aagttgatag atgaagaagg
     4081 agttgtagtt aatattgata atgaaatatt aactaaagta gaagtagtaa atgatgataa
     4141 tgaaatagaa gaaaaaataa tagaagaaga ttggttaatt agtgaaaata ccataaaatt
     4201 agatgataaa gaagcaatta ttaatgataa aaacatagaa ttatgtaaaa aagaagttca
     4261 agttgaaagt gaaaaaatag gtttaaataa gtttgaagga cttgaccaaa atgaaaatta
     4321 taatctagaa aaaaatgtta ttgaagaaaa aaaagtaagt gaatgtttga cagaagaaga
     4381 tttagagtac ataaaagaaa ttaaaataaa aagaggaaaa agtataaaag ctataaactt
     4441 gtatactaaa gaagagtggg tttttgacac tcatatacag tgtagtaaaa aactcaaagt
     4501 tccattaggg tacataagag aaaatttaaa atatggatat atggattact ttggagatgc
     4561 aataaattat ttaagtgaag tattaaatat agatgaatac tgcaaaagtg aatggagcta
     4621 tctcgataat agcaaatctc catctgagat atttaatatt ctaaacaata aaatatttag
     4681 tataaggctt tctaatgaaa aaagaaatga aattttgaca aatgataaaa ttgaagcatt
     4741 aaaaatgaat tatagatttg aatgtattga tgaagaatat gatgaatatt ttaaaaaata
     4801 taagtctata atcaaaagag gtggaaagaa aaaagttgaa ttagtaaata aaaaaggtga
     4861 cattttagaa atatttaagt ctttagaaga atgtgccatt tatttgcaaa aggaaaagaa
     4921 tgaagttata caaatgttaa aatatggaga tacaaaagta ggaagaaact ttataaggta
     4981 tagtttgaga agtatttaat ttcattttaa attcataaga gtttcatttc tgattcacac
     5041 atttaatatt attttaatgt aaaataataa aggtgaagta ttgcacaatt aaaattaagg
     5101 agggtattaa tgtctgaaga aaaaaatcca aaagaaaata cattagatga atctaaaaat
     5161 tcagataatg taaattctaa aaaagatgat gtgtcagatg aaaaaaatac tgataacaaa
     5221 gttaaaaaaa gggaaataaa gctaaacaac aaaacactta aagctattgt agcaattgtt
     5281 gcagtaggag ctatatgttt aggtggaggc tatgtttttg gcaaagaagc tggaagaaaa
     5341 ttgcctgcta cttcaaaaca ctataatagc agtgaggtag tagctactat tggggataaa
     5401 aaaataacag gtgaaatgtt aagaaagaga atggagccat tattttattt aaatgcaaaa
     5461 actactatga ctgatgacga aatacgttca tatgaatcaa atatgattga aactatgatt
     5521 acatctgata tattatcctc tgaagcagca aaagagaaaa taagtataac taatgaccaa
     5581 ctagatgctc agtataataa tttaatgagt agtatagaat cagcaatggg aatgactaaa
     5641 gaagagtttt taaaacagtt tgatttgact gaaaaatata taaaagatga tatgaaaaaa
     5701 gagctagtag catcaaaata tttaaatgaa aaatcaaaag ttactgataa agaagcagag
     5761 aactattaca ataaaaacaa gagcaattat ttacaagtta gagcttcaca tattttaata
     5821 aaaactgttg atgataaagg taagcaagtt agtagtagca aaaaagctga acttaagaaa
     5881 gaagctgaag aaatacttaa aaaagcccaa gctggggaag attttgctac tctagctaaa
     5941 aaatactctg aagatagtag tgcagaatca ggtggagatt taggtttctt tggtaaaggt
     6001 cagatggtgg aatcttttga aaaagcagcc tttgcattga agaagggaga ggtatctaac
     6061 aaacttgtag aaagtgatta tggatatcat ataattaaga aaactgatga aaaatatcag
     6121 ccatttgaag aggtaaaatc agatttagta agcagtttaa catcagaaaa acaaaaccta
     6181 cttatacaaa atctaaaaga aaaatataat gttaaaatta cagataaata tcaaatgaaa
     6241 gctaaagaat agataaagtc aatttattaa aaaaaagaaa aattaactgt atggataaaa
     6301 gctattttta ctcttaatat agagagtata aaatagcttt tattattttg caataaaatc
     6361 tatttatata tatgaagtga caaagaaata acatgcaaaa agatattaaa aagaaatatt
     6421 tttaatttga attttttcaa taaaaattta caaaaatgaa aaaacaaaca aaaaagaatt
     6481 gaagatttaa gttgttattt aaatatatat atattaagat tttctgctga agatactaaa
     6541 aaaataatat ttttcataat tttaaaaata ataataaaaa aatgaaaata caggcgataa
     6601 tctattgagt aaacatagaa aagatgatat tataagtatg tgctaaaatg gttaaagcaa
     6661 tattaatatt aaatttaact ataaaacaaa agggggcgtt tttttatgtc aagtacagaa
     6721 agcgtatcta aaaaaagtgg tcatccgaag agtttttggc ttatttgcat gacaattttg
     6781 tgggaaagat ttagttatta tggtttaaca gctttattgg tattattttt tacagcaagt
     6841 gtagctcaag gtggtttagg tctttctact caagaagcaa catccatgtt tggcttattt
     6901 acaggtctta tatatcttac accattagtc ggtggctggt tagcagataa agttttaggt
     6961 caacaaaaat gtatttctat aggtgcactt ttaatagcaa taggagattt cgtactattt
     7021 gcttcatcta catctattgc aatggtttgg gtaggtctat caataattat tttaggaaat
     7081 ggttttttta aatcaagttg ctcaaatata gttggggata tatatcctaa aactgatgtg
     7141 tcaagaaaag atgcagcata cagtttattc tatatggcag taaatgtagg agcatttata
     7201 gctccaataa tatgtggatt gctttctgat aatgtatttg cagtaagagg agcaagtgga
     7261 gatatagtat cttatggata taagatggca tttttaattt gtggtatagg catgatgtta
     7321 ggtatgatta tatttacact tcttgcacca aaattattaa atgaagtcgg aaaatatcct
     7381 gtgactaaag gtaataaagg tgaaaaaatt gagtatggac cacttactaa gttggagaaa
     7441 aataggataa tagcaatggt tattttattt ttatttgtgg tcttattctg gacagcatac
     7501 tatcaaacac aaagttcttt tatgatttat gtaagggata atgtaaatag aactctattt
     7561 ggatttgaaa tgccagtagc atggcttaca tcactaaatg ctatattatg tgtggcttta
     7621 tgcccagtat tagctaccct atgggttaaa ttatctcata ccaaaagagg tgatttctct
     7681 attccagtta aaatgggatt aggaatgata ataatgggtg ttgggtttat agttatggta
     7741 tttgctacat tagctaatgg tccagatgga atggtaaagg ctagtatatt gtttatagta
     7801 ttgacttata tatttacaac agtaggtgaa ttattcttat ctcctatagg acttgcaatg
     7861 ttcaataaat tagctccagc taagtatgct acgttgtcta tgggagcctg gtatctaaca
     7921 agtttttttg caagtttatt atcaggaaag attgctggtt ttacagccac acttggtttt
     7981 ttacagatat ttggaggaat agcaacagtt ttaataatat ttggtttaat attattggga
     8041 ataagaaatg tattaacaag attaatggct atggatttac taacaaaaga aaaataattc
     8101 atgacgaatt attgtaaata aatgaattac tttaaataaa ggaagttaca tttaaatata
     8161 aaattaaatg taatttcctc tttgattatg aaaaaaagct ttacacaaat agatattata
     8221 attaaaatta taattgtgat aattagagtg tataagattt atataaatta tacaaaaaat
     8281 atttatgtaa taaactttac atacttatat atttagttat tcaaactatt atttcgagga
     8341 ggtcttgttg tgaatataaa agatagatta agtggattaa gaaaatttat ggaagaaaaa
     8401 aatatagatg cctatatgat tccatcttct gataatcacc aaagtgaata tgtaggagat
     8461 tacttcaaat caagagaatt tatatcaggg tttaatggtt cagcagggac ggttattgtg
     8521 actaaagacg aagctgggtt atggacagat ggaagatatt ttatacaggc agaatctcaa
     8581 ttagaaggaa gtacaataaa attattcaaa atgggacaag aaggttgccc aactacagat
     8641 gaatatttat ataaaaatat tcctgaagga ggaactttag gatttgatgg tagagttata
     8701 tctgctagag aaggagctac attagctgaa aaattatcta aaaaaggtat aaagatagaa
     8761 tatcagtatg atttaataga tagtatatgg ccagatagac ctgctttatc agatagtaaa
     8821 gcatttttat tagatgttaa atattgtgga gaaagtttta gctcaaaatt agctagatta
     8881 agagaaaaaa tgagtgaaaa aggtacttct actcatgtaa taactactct tgatgatata
     8941 gcatggttat tcaatataag aggtggagat gttaaatata atccagttgt actttcttat
     9001 gcagtaataa ctttaaaaga agtttatcta tttgttgatg aaagtaagtt aaatgaagaa
     9061 atactaaatg aactagctaa ggaaaatgtt caaataaagc catataatga tgtgtatgaa
     9121 tttgtaaaaa atatagacaa aactgaaaaa gttttattag atggaactaa gcttagttat
     9181 acaatttaca ataatatacc ttgtgaagtt gagaaagttg atgagttcaa tccagtaatg
     9241 ttttttaaag ctcaaaaaaa tgaggtagaa ttagaaaata taagaaattc acatgtaaaa
     9301 gatggtgtag ctttcactaa atttatgtac tggttaaaga aaaatgtagg taagatggaa
     9361 atcactgaaa taagtgctac tcaaaaatta gaggacttaa gaagagagca agaaggtttc
     9421 tttgagccaa gtttcaatac aattgctgca tataaagagc atgctgcaat gatgcactat
     9481 agtgcaactc cagagtcaaa ttataaatta gaggcagaag gattattttt agtagattca
     9541 ggtggacaat attatgatgg aactactgat ataactagga ctacagtttt aggacctata
     9601 agtgatgaat taaaactaca ctttacttct gtagcaagag gaatgataaa tctttctaag
     9661 gctaagttct tgcatggttg tagaggatat aacttagaca tactatctag aagttgcatg
     9721 tggaatatgg gaattgatta tcaatgtgga actggacatg gtataggatt tgtgctaaat
     9781 gttcacgaag ctccaaatgg atttagatgg agagtagtac ctgaaagatt tgatagtgca
     9841 gttcttgaag aaggaatggt aactactaat gaaccaggta tatatataga aggttctcat
     9901 ggtataagaa cagagaatga aattgtagtt agaaaagctg aaaagaattt ctatggtcaa
     9961 tttatggaat ttgaagttgt tacgttagct cctattgact tagatggtat agtaccagaa
    10021 ttaatgaata aggatgaaaa agattattta aactggtatc ataagttagt ttatgataaa
    10081 atatcacctt tcttaactga tgaagaaaga gaatggttaa aagtttacac tagagctata
    10141 tagtttgtac tagatacaat aaaaatcgag gtattataat gcctcgattt tttattgtat
    10201 attttattaa ctttaaaaaa tttttaattt gataattcta ctaatttttt attcattata
    10261 agtagtataa ttccaaatat caataaaaat gatggtatca ctatgaagac ttgtaacata
    10321 ccaagttggt ctataatagc ttgcgtatag ccagataatt tatttgctgc aaatttgcct
    10381 aaaaaccaaa cacccattag gaatgaaata tacttttcag gcgaaagttt atttaccata
    10441 ccatacccga ctggagaaaa gcaaatttct cctatacttt ggaatgttaa aaatccaact
    10501 acccaaaata cacttgcttt gtgaattgaa ttagggtctg ttcctgtttg tataactgct
    10561 actatcataa acaaaaatgc tatggctaat agtataaaac ctaagctcat tttttttggc
    10621 acacttaaat cgcctttttt agtttgagat aattttaccc atactaaagc agagataggt
    10681 ccaagaataa cacaaaggag accattgtat gaatctatcc atgaagtagg aatttgaaaa
    10741 ttgccaacag taagatttat gtgttccttt gtatagagtg caatagacat agaggcttgg
    10801 ttatatgcta tccaaaaaaa tactgtgaaa aaagctaaca ccaatattac tattattctt
    10861 tttttctcaa tcaaagttaa aggtcttgaa gctagcattt tcttatattc tagtgatttt
    10921 cttatagact ctctcccgtt actagggtca ttattcaaag gtttataaaa ctttctgttt
    10981 ccaaatataa agaagaataa acctattaga accgtaattg atgaaaataa aaatacatat
    11041 ctatatccat acatacttat agataatccg cttttcatag caaaccattc attagcaact
    11101 aaaccgcata ttaaagggcc aaataaggta cctagattag tagccatata cgtaatagag
    11161 aaagctccat cttttcttgg gtcatcattg gtatataagt ttccaaccat agtatgtaag
    11221 tttcctttat aaaaacctat tcctaatcca gataaaaata tcatgatgtt tatatccatc
    11281 ttactatttg ctatgtatcc tagaaaataa ccaattgaaa ccattagcat tccaagtata
    11341 atacagtttt tgggacctaa aaatctatca ctgacccatc caccaataac tggagagaaa
    11401 taagtccatg ctaaaaaaga tgcaagcatt gatgcggatt ctgctggtgt taaccctaaa
    11461 ccacctttgg agacttgttc agctaaaaac aataataata ccaatttcat accatagtat
    11521 gcaagtccta caaaggtaaa tattgaacag cagaaatata aatctctagg ttgtttaagt
    11581 ttttcttgcg tttttaaaac tgacatatgt cgagaacctc cagataaata gtttaacaaa
    11641 attttaccat actatatgag tatatgtttt tttcatatag acgtcaactt gtaagataat
    11701 ttaattaagt cgaaatatat gtaaaaatag tatcattttt gtgtattcag taatattttt
    11761 ttatgataat atatgttatt attatattaa aatacaaaca tatttatgga aaggatatgc
    11821 caatttagta gttagattga ttgtttggca ggtgggatga gctatgataa gaaagaaatc
    11881 tgaattacaa gtagaagtaa aagaaaattt aaatggtggt ataggaaagg ttaagcttga
    11941 aaacataata caaaatgaag agcttaaagg aaaaggaaga ctatttaaaa gagtagcttt
    12001 accagtagga agttcaattg gtgtgcatga ccatacaaca gattttgaag tatattatat
    12061 actaaaggga aaaggtaaag tatttgataa tggggaattt gtagaagtaa atgagggtga
    12121 tgtagtgtat acagctgatg gcgaaaaaca ttctatagaa aatataggag aagaagatct
    12181 tgagtttgta gcactagttt tatatatgta aaatatggag gaggagtcat gacaggcaag
    12241 atagaagaaa ttaaggacaa gataaataga ttttgcaact ccaatttaaa tcaagaatac
    12301 aaagatataa gctttaaaat tttgcaaaac cttttagata ataataaaga gataattcat
    12361 tcttctagag ctgatatatg gtcttcagct atactaaata tagttttaga acaaaatctt
    12421 ttatacaata agaagcatcc actacatata acaaaaaaag agttttcaaa acaaataggt
    12481 gtttctttaa atactataaa taataaatcg tctttaataa aagatgtttg tagtattgac
    12541 tttttaaatc aagatactat agctatttct aatgtagaat tttgggtaaa agagaccaat
    12601 tccaaatcaa agtctgtaga tttagattta gaaaagaaaa aaatactata taaaagatat
    12661 attaagctat cacaagatgc gaatagtgat attgaatcaa ttagatatat ggaggaagct
    12721 gtaaatatag gtaaaagtat gattactaaa gaagataaag aacttggatt ttggaaaggt
    12781 ttatctacca gagcctatat gatagcactt gaatcccttg ctagaaagtt agaaagtatt
    12841 aataatctaa aggagtccaa aaaagtatta gaatatttaa tagaaattaa tcctagtgat
    12901 gagcagggaa taagatacaa attattaaat gtattaatta gattaaatga tagaacttca
    12961 ataaataaat tatttgaact ttataaagaa gaaaaatctg ctacatggat gtacagtaaa
    13021 gctctttatt actttaaaaa taaaagtatg tttttggcaa atgattctat taaggttgct
    13081 agaagtaaaa ataagtacgt tggattatat ttgttagatt ggcgaaatgc ttttggtaga
    13141 gaatttgtta cagaggaaga aaaggcagaa gctgtctatt actatgatga aaacatagtg
    13201 atttggaatg aagttaaagg ttctatggat tggctattaa aaaaaatgtt ggaattttca
    13261 taaaaaaaac tactccttac ttttatataa gtaaaaggag tagtttttaa tttatacatc
    13321 tagttttaaa tcttcaggtt ttattagacc tttttttctc ataaattctg aaatcaacaa
    13381 agttacaata gcaggaagta taaaattaag taaaagtata ccaacccaca tagatatacc
    13441 tccttttcca gcactttgca tagcagttac tgttccaaat tgtccaacca atccacaagt
    13501 acccatacca gaaccaatag gaatattctc cattttgaat attgttgtag ataatggtcc
    13561 aagtaatatt gaagctacag taggtggtat ccaaattttc caatttttta ttatattagg
    13621 tacttgcaac atagatgtcc caagaccttg tgccacaagg ccgccaactc cattttctct
    13681 aaagctcata acagcaaagc ctaccatttg gcaacaacaa cctacagttg ctgcaccacc
    13741 agcaagacca cctaaactta acatcataca aatagctgca ctacttatag gtaatgtaag
    13801 agctattcca acaagtgcag agactaaagc tcccattatt ataggttgca tagttgtagc
    13861 ttgcattatt atatttccaa atgaagtcat aaaagcagaa acagctggac caataagttc
    13921 agctacaagt actccaatta gtattgttac agcaggtgta accaatatat ctatttttgt
    13981 ttcttttgaa actaattttc caacctctac agcaaaaagt gtagcgacaa atgctccaac
    14041 aggtcctcct aattcattac cacaagctcc aacaagtgca caagaaaata gtacaagtgg
    14101 aggtgcttga agtccatacg caatagccac tgctatagct ggaccagtaa cctgtttagc
    14161 aagagggctt ataacttcag taaaaagaga aatattgaaa ttatctccta atgtattgaa
    14221 aattgttcca attaaaaggg acgaaaaaag accgagtgcc atataactta gtgcgtcaat
    14281 aagatacctt tgaacagaaa tttcaatatt ttttctttta gcaaatgatt tgaaatttct
    14341 ttttttataa ttgatttcca atttaaaatc ctcctcatat aatataagta taatttcttt
    14401 ttaattaatt atataacttt tcagctgaca agacaaatgt tatttcacta aaattagact
    14461 attgtaatag taagaaatta acattaattt tagttttaaa ttttaaattt atggtttata
    14521 attagtatag ggatattctg aaatataata attttccagt ttatcccaat atttaactta
    14581 ggtagattgc ttacaaaaca aatgattata tattaggcta aaaggaagtg gatagatgat
    14641 atttgtaaaa aataagaaat acagaaaaat tgccataatt atatctattc ctatattgct
    14701 tgttgcgcag tactaccttt ttaaatttgg aatacttaga ccaatggtaa agggagtaga
    14761 aattgaaatt gtagatgggg aatatgttaa agatatagat aaatatgtag taaaattaaa
    14821 tgaaacagtt actttgtcta caggtgaata tattaaggtt ccttcgtatg ctaaaaatcc
    14881 aaatatttgg tttaatgtat tggataactc agggacttta aaaatagatg gaaataaaat
    14941 gacagcatta aaggttgggt attcttctgt gggtatcatg aaaaattcaa gagtattaaa
    15001 aaaggctact ataaaagtag tagacccaga ggtagaatca ctagatatgg agattaatgg
    15061 ggatttaaaa catgttggtg atagtgctac tatagaaagt acaatagaag ttgattatga
    15121 taagtttaaa aaatcatata agccagttta taagagtagc aatgaaaata ttttaaaaat
    15181 caaaggaaat aaagtaagtg cagttggagt tggtaaagct acaatatatg ctaagtgtgg
    15241 aaataaagaa attgagagaa catttaggat tcaagctaga gttgctgaaa taaatatgga
    15301 tgatataaaa atagaagttg accagaatga aaaattgaaa ccagatataa taacttctcc
    15361 acctggttta gaaccaccaa aaatatatta tgagttagta gattcaaaat tacctgtaga
    15421 aagagcaata agtttaagta gtaatggaaa tgttgtaggg cttagagaag gtaaagatag
    15481 ggtgagaata acttgtggag ataaatctaa agtaataaca gtaacagtag tcaaagaaac
    15541 tataacgaat gactatatac aaaacttggt tggttcacat aaaatagtaa acaataaagt
    15601 tattattaaa cttgaatggg attatatgaa agatgtcttt gattatgata tatatcttaa
    15661 agataagttg tcaggagaat catttaagaa aattaaatct ataactataa atgaaagtga
    15721 tttaggtaag tctaacaagg tatatgcaac tatagaagta gatatgaagg gtaatcaaaa
    15781 tatagatttt gatatttatg tcataggtaa aaaggattca gatacaacta agccaagtaa
    15841 tgtaataaat attaccaatg gaaatggaaa ttcaaataat gataataata ttaaagatat
    15901 gagggtagaa aatatatcag ctaatgttga tagagataat aatgtcatta gagttaactg
    15961 gagtagtata tctcataagg actgtactta cagtatatat gtaaaaaata atactaatgg
    16021 agatggagaa tttactctat atcaaagtga tatacaggga aatgagcata ctataagtat
    16081 tcctgaagga gatttaaatc tagatattta tgttgttgca aattataatg gaaatagctc
    16141 tcaaaatagt gatgttataa atgtaagata gatttgtata caaattgaaa gtgttgagtt
    16201 tatttaaata ttaaattaag aaaaaggata gtatagggta attatactat ccttttttgt
    16261 tacaatatat aggtttaaaa tctctagtaa tataaattat aaaaagtctt atttacacaa
    16321 atctatagat atttttttta ttaatcaata ttgtcttaaa ttgaacttag tgcggcttct
    16381 attgcatgta ttactgtcgt atcaaatagt ggaatagaag tgtcattttg tttaattaaa
    16441 agacctattt ctgtacatcc taatataaca gcctctgcac cttgtttgcc aagcttatct
    16501 ataatagata agaaagcttt ttttgaagat tcagatataa ttcctaagca aagttcatta
    16561 aatattgtgt catttactat tatacggtct tcttcatttg gaattaagac ttcaattcca
    16621 ttattaataa ttacattttt ataaaaatct tgttccattg tatatttagt acctaataag
    16681 gccacttttt ttatttcttt ttcccttaat accgtagcag ttacatctgc tatgtgaagt
    16741 aatggaatat gtatactttc ttgtatttta tctgatacct tatgcatagt attagtacag
    16801 ataacaataa aatctgcccc tgcctcttgt aatttaattg cagcatcagc taaaattttg
    16861 gcgctttttt cccaatttcc actagattgg cattcttcaa tttcttgaaa atctacactg
    16921 taaagtatac atttagaaga gtgtagtcca cctaatcttt cttttattac tgtattaata
    16981 acttgataat atgtaatggt actttcccaa ctcataccac caattaagcc tatagtcttc
    17041 atattatacc tctcttattt atttattttg aaatagctat ttacaaatac aagtatagca
    17101 tctaaaatag aagcatacaa taataaaatt gtatggagta caattataat taagaggagt
    17161 aattatatgc caataaattc ttttgaaaac tatcctatga catggaaacc aaagttagat
    17221 aaccgaaaac caccaatata taaaacttta gcaatgttat tagaagaaga tattaaaaga
    17281 ggaaatttaa atcctggaga taaattgcct ccacaacggg aattagcaga ttttctagat
    17341 ttaaacttaa gtacaataac acgagcattt aaactttgcg aagaaaaggg actaatatgt
    17401 gcaaaagtgg gaaagggaac attcatttct tctgatgtaa atgtaagtaa tacattatta
    17461 tatcaaacgg aatcaaaaga cataattgag ttggggacag ttcatcctcc gtatgagcaa
    17521 aatacatata ttattgactt tattaaaaat gtactaaaac aaccagaaat ggataggttt
    17581 ttacaataca tgtctccatc tggcacatat atgcaaaaaa agtcaattgc aaaatggata
    17641 gaaagaaata atgtatacac cagtgaagaa aatatattat tatctacagg agggcaaaat
    17701 gctatatgtg caactttact aggattattt aaagctggtg atagaattgc tacagattct
    17761 ttaagttttt ctggaattaa gtcaatagct aaaatgatag gtattcaatt agtcccaatt
    17821 cctcaagaaa ataatgaaat atcgattgaa tatcttgaaa gttattgtaa aaatgaaaat
    17881 ataaaaggca tatatcttat accagattat cataatccaa cgacacatac tatgtctgat
    17941 ttatctcgta aaaagatagc caagatagca aagcaatata atataataat tattgaagat
    18001 gctataaata gcatttttag agatggtata caaactccca tattttcttt agctagtgat
    18061 aatactatat atatttttag tacatctaaa tttttatgtg ctggtcttag agtagcattt
    18121 gtagttgctc caaaacgata tatagaaaat ttagaaaatg cactatataa tatgaatcta
    18181 atggtttctc catttacagc agaaatagta caccgtttat tatattctcc tattatagat
    18241 aaaattatag aagagaaaag agatgcaatt atagaaagaa atgaagttgc tgataaagtt
    18301 ttgtcagatt ataatttgat tggtgataag aattgcagtt ttcgttggtt acttcttcct
    18361 gatgaattgg atggaaaatc atttgaaatt tctgcaaaaa atctaggagt tcaagtatat
    18421 tgtgccgaac gattttcagt aggaaactct acagttccaa aagcagttcg tatttgtgta
    18481 acagctccaa aagatgtaga agaattagaa aaagggctta atataataaa gtcacttctt
    18541 aagagttaaa tttattttac tattatttaa ttaaataaat aaaaaggcgg agaaatttat
    18601 tataataaac ctccgctttt attatttaat gaaatacttt actttttatt aaaaaattta
    18661 attttaataa tcttgaaaat ataatcgttt tatggtaaaa taattcttaa aaatagaaaa
    18721 aattaatcat ttgttaaaaa aaatgcataa tttattgtaa tttattgacg aaggttgaaa
    18781 aatattcata aatgtgcgaa ataacagaaa aaatgcaaaa attaattcaa tttcatttgt
    18841 tataaaatct atatggcaaa attaaatctg cctatcagaa tgatataaac acatcagaaa
    18901 ggaggacgct atcaaataat acaagtagtt aactttgata gcaaaaaatt atgaatgaac
    18961 aaactagaat atccttagag agagctgctg aattaaaatc aaaaattgat gattatattc
    19021 aggctagaaa aacgattaac agaggtcttg aaaaagaaga agagataaat aaacgaaaac
    19081 agaaaatatt aagtatctta aatggaactg aagaggattg gaataactac aaatggcaat
    19141 tatcaaatag aataacagat gtagatactt tatcaaaaat tataactcta actaaaaaag
    19201 aaaaagaata tataaaagag gttggtactc aatttagatg ggcaatatct ccatattatt
    19261 tgagtcttat agacccagaa gatatatgtg acccaataaa attactgtct ataccaacac
    19321 atatagagtt ggaagatgag caagaagatt tggacccaat gggagaagag tatacaaacc
    19381 cagcaggatg tataactaga agatacccgg atagattaat aataaatgta acaaatgagt
    19441 gtgctatgta ttgtagacac tgtcagagaa gaagaaatat tggacaacaa gattctcata
    19501 agtcaaaagc tattatccaa gaatctatag actatatcag agaaaatgaa gaaataagag
    19561 atgtactagt aactggtgga gatgctctta cattaaaaga tgattattta gagtggattc
    19621 ttagccaact taaagagata ccacatgttg attatgttag attaggtact aggactcttg
    19681 ttacaatgcc acaaagaatt acagatgaat tttgcaatat gctaaaaaaa tatcaccctg
    19741 tatatataaa tactcatttt aatcatccaa tggaaataac taaggaatct aaagaagctt
    19801 gtgaaaagtt agcaaatgca ggcgttccat taggaaatca ggcagtatta ttaaatggaa
    19861 taaataatga taaatttgta atgagatgtt taaatcaaga attactgaaa ataagagtaa
    19921 aaccttatta tatattccaa agtaaacatg taaagggaac aaaacatttc aatacatcag
    19981 tagatgatgg tcttgaaatc atggagtatt taagaggata tacatcagga atggctatac
    20041 caacatatat agtaaatgct ccaaaaggag gaggaaagac tcctttgctt cctcaatacc
    20101 ttgtatcaaa aggaacagat tacgttatgc ttagaacatg ggaaggaaaa gttataaaaa
    20161 tggaagatga acctgctgta gatataaaga aacttataaa agaacaagca caggattaaa
    20221 aaaatattta aagtttataa aaagaaacaa ctttaaaata aaaagaaaat ggatgtcaaa
    20281 tttatatcaa tttgcatcca ttttttatta gttatttatt attttgttgt tgattaacta
    20341 attcaagata tccacttggg tggaagtaat atatctcaga agtattttca tttacaaagt
    20401 aaccaatatc accatctgca tctggtaaaa atacataacc attaagattt ttagctttta
    20461 atgcttcaaa atcactagca tttccttgat atatgtaatc aacttcattg ttgtatttta
    20521 ctaaaagttc tttagcttgt tcttgagtca atttagtatt ttggcttaca ggaacattct
    20581 tttgagaatc tgcataagaa gattcattta ctggtgcagt taataacaaa caagataaaa
    20641 ctaataaaga tataagtgct tttttcatac taaaaccctc tttcatgttt aattatataa
    20701 gattcattac ttaataatat tgtatgtttc ctataattaa atattaccat taaagagaat
    20761 aatattacag ttacacagct gtaacttttg attacaaaat cgtaattaaa ttgtattttt
    20821 attccatttg tattttatca tgtctacgat ttacaaactc acagaagtat atctttataa
    20881 cgcccatcac aggagcagat agaatcatac caggtatacc aaagaatcct ccaccaacag
    20941 taactgctag gattgtaaag aatgggctaa gacctagttg tccacctacg atttttggct
    21001 ctataaatgt aacttcaact tgttgaatta ttattaagta aattaaagaa gttaaagcaa
    21061 ttgttggatt ggagaataaa ttaattatta caactggtgc catacctatt actggaccaa
    21121 aatatggaac catattcatg acacccataa gtgtaccaaa taatagtgca tattcagatt
    21181 ttaaaaagta aagaccaatt ccagaaagta ctccaactat aaaagaatct aaaatcttac
    21241 ctgtaaagta tttaccaata tttaaattta agctttgaca tagttctatt ataaagtctc
    21301 catatttttt acctaaggaa atataaacta ctttttttgt aaacagtaag aatttttctt
    21361 tttctaataa tatatagaaa caaattataa aacctaaaag aaattgtact ataaattttc
    21421 caactgaaaa tgtagtgcta aatatcccac caagtgaacc aataagcaag ttactaaatt
    21481 taggcattac actcataatt ttgtcaccat actcttttaa tgtattaggg tcaactgatt
    21541 gtaaactctt gcctaagtcg aataaaaact gctctgtttt atctatgtat gtaggaattt
    21601 gagcaactaa atcagctaaa ctatttacta tggatggaac tgtaaataat ataaacgaaa
    21661 ttagtataac tatgagtaca ccataagtaa gaagtaacga atatattctc ttaaaattta
    21721 atttactttc taagaacttt actagtgggt tgaatatata tgctaataca aatgctatta
    21781 taaatggtgt tagtagtgac attaataaac ttatcactcc aaaaaaatat ttgtaattat
    21841 caataacttt aatcaagata tatgaaacaa ctacagtgag tacaatattt agataaattt
    21901 ttttatcttg caa
//
LOCUS       DAEPKC010000065        21719 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.065, whole genome shotgun sequence.
ACCESSION   DAEPKC010000065 DAEPKC010000000
VERSION     DAEPKC010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21719)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21719)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21719
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.065"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(<1..839)
                     /locus_tag="KR294_002491"
     CDS             complement(<1..839)
                     /locus_tag="KR294_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240561.1"
                     /translation="MNDELLKKVYTSSFSSASRALKDLTIINTKSLIDDKTQRCVYID
                     ENRLRDELIYYRFYGEKIGNINFLNILLPLILSNTNIQKSEDEVIKLIKKYVIYFKKE
                     ELLFDYLLGSVVYNSIMHNLINNSKIEYVELLQSIKDKIIGFSIELDKSDVVKFQMAR
                     IKAIQLIDKYIDLKSEDYDEESILLNVLNVLYDVYMEDRTVENEGINSIKKSILSILG
                     EDSKLNEDNIDFIFSMSEYVVKLRKYKIGVKAYNKSIDPRSLIRLEEGNTIVDPIFNQ
                     ITV"
     gene            complement(1093..2793)
                     /locus_tag="KR294_002492"
     CDS             complement(1093..2793)
                     /locus_tag="KR294_002492"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HBH0240562.1"
                     /translation="MQDFKVAISNCLKEKIEDLSKEEIEALIEVPPNKDMGDYAFPCF
                     KLAKVFRKAPNMIASELAESIEPSGEITKVIQLGGYVNFFVNKSQLAETVIKKVLDEK
                     ENYGHSDFGKDKTVIVEYSSPNIAKPFHIGHIRTTVIGNALYKIYDSQGYKTIRINHL
                     GDYGTQFGKLIVAFKKWGEKEVVESNPIPELLKLYVRFHDEAEQHPEMEDEARAWFNK
                     LENGDEEAQELWQWFRNESLKEFNRVYKLLDIEFDSLAGESFYSDKMNRVIELLEEKN
                     LLKESKGARIVDLEEYKMPPALITKNDGSTLYMTRDLAAAIYRKETYDFDKCIYVVGS
                     QQNLHFQQWFKVIELMGYDWAKDLIHVGFGMVALEEGTMSTRKGRVVFLEDALNQAID
                     KTKEIILAKNPNAKNVDEISKQVGVGAVVFQELSNSRIKDYTFSWERTLSFDGETGPY
                     VQYTHARCCAVLRKAEVEVTSDIDYSLLADEDSAEVLRVIESFNKNILLALKKNEPHI
                     VTRFMLDLAQAFNKFYHDNPILVENLEIRKARLALVLATKQTLENSLKLLGMHAPERM
                     "
     gene            complement(3203..3616)
                     /locus_tag="KR294_002493"
     CDS             complement(3203..3616)
                     /locus_tag="KR294_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HBH0240563.1"
                     /translation="MILVSACLIGINCKYSGDNNDNEKVKEYLKGKEFTLVCPEQLGG
                     LSTPRPPAEIVDGKVITKDNKDVTENFVRGANETLKIANLYVCSEAILKEGSPSCGCN
                     LIYDGSFSGKKIPGKGITARLLEEEGIKVKSEKDL"
     gene            complement(3682..6060)
                     /locus_tag="KR294_002494"
     CDS             complement(3682..6060)
                     /locus_tag="KR294_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HBH0240564.1"
                     /translation="MNEKSLRVLEYNKIIDLLKKKASSSLGLKYIENLVPNTDFVEVK
                     SMLEETSEAQSIIIKRGSVGLEGIHDIEDKVKRAYIGASLDPGSLIMIADTLRVARRL
                     RNSLSSSDEEDFNYPIIQSLSNSLYVYKDIEDQIYNAIISEVEISDNASSTLRDIRRR
                     IAQKNQSIRSKLNSIISSTTYQKYLQDAIISLRGDRFVVPVKSEYRSQVAGIVHDQSS
                     SGATLFIEPMTIVEMNNELRQLKLGEQEEIERILSELSAMVGEVSEDLISNQEILGRL
                     DFAFSKGKLSIQMRGIEPTLNEDKYLNIKNGRHPLLDKKKVVANTIYLGRDFHTLVIT
                     GPNTGGKTVTIKTVGLFALMTQSGLHIPADYGSSMCVYDNVFADIGDEQSIEQSLSTF
                     SSHMTNIVSILQNVTADSLVIFDELGAGTDPVEGAALAIAVLEDINSVGAKCIATTHY
                     SELKNYALTKPGVENAAVEFDIETLSPTYKLLIGVPGKSNAFEISRKLGLSDYVISRA
                     KEYINTENIALEDVLQNVEKNRIKAVEDREEAERLKEEIEKLKVEYDEKLEKLVSQRD
                     KMIEKAKSEAFSIIRQAKEEVDIIIKELRSLEQERASKEKNRKIEELRKELTSSMGSL
                     QPTVKSMIVPKVSNKEIKDLKPGEEVKVITLNQNGSVVSVDKKRKEAVVQIGIMKMTL
                     PFKSLQKTRKDVSTNVTKSTRNIIRSKSGSVKNEVDLRGLNLEEAIMEVEKYLDDAYV
                     AGLESVTVIHGIGTGVLKAGLQDILRRNRHVKSQRGGQYGEGGAGVTIVKLK"
     gene            6379..7830
                     /locus_tag="KR294_002495"
     CDS             6379..7830
                     /locus_tag="KR294_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-histidine dipeptidase"
                     /protein_id="HBH0240565.1"
                     /translation="MGNVLEGLKPESVFKNFEKISQIPRGSGNEKGISDFLLSFGKNL
                     GLETIQDESLNIIIRKPATKGYENCPGVVLQGHMDMVCEKEKNVEHDFLKDPIKLRID
                     GDMIYATGTTLGADNGIAVAMGMAILEDNTLEHPALEVLVTVNEEDGMNGADALDPSL
                     IKGQYILNMDSEEEGYLLVSCAGGKTCVVSLPVEYKEVKGDKQGLLVEVTGLLGGHSG
                     MEIVLQRANANKAIARVLSVLNVDYELASVDGGTKHNAIPREAKCVIAVNKADVESAK
                     KQINDILTAFKHEFTTSDPGMTYSVAETSVDKVLTKDCKEKVVQMSCLTPHGVQSVSL
                     DIEGLVESSTNFAIIETKESTIEFLTSVRSSVMSIRDEIADRIRLLAQALGANYDLIA
                     QYPAWEFKKGSKLEKICSETYEKLTGKVPTVMALHAGLECGLLLDKLPHAEAISIGPD
                     MFDVHTPNEHVSIPSVANVWDYVIEILKSMNQY"
     gene            complement(8034..10547)
                     /locus_tag="KR294_002496"
     CDS             complement(8034..10547)
                     /locus_tag="KR294_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HBH0240566.1"
                     /translation="MEDCVVNLKKLLLLIIVITSIFTSCIFSFGINAIGNDNRTIRVA
                     YPIQKGLTEIDEQGNYFGYTYEYLLEIAQYTGWNYEFVQVPGEINESITKLMKMLENG
                     EIDIMGGMLYNEPMQKIYNYAGNNYGVANTVLQALYENTDIDNIMSSQDVKKIRIAVI
                     ENSDTRLKELDEYCKMNLMSPELVYCKTNDEQLEALKSGKADVLLNVSMNPIEGVRTV
                     AKFSSKPFYFITPKGSTNLTQKLNSAINNIEQKDPYFSTTLYEKYFTPENNQMFLSDE
                     ETNYIKETEKLKVGVLLNKPPFQNIDKDTGELRGISIDLLNHICDKTGLEFELVPVKS
                     QEDLENMTKKREIDIVAGMIYDYEYSREHNIAMSRPFLSTQYTMMINNKLNENSLDGK
                     RVALAKGINYYGQFEENIVWYDNLEECIEAVNKGYADYTYGEGYSMQYYMNQPKYKNV
                     RLVPQTYKAKSICFGIIKKDKQELLNIFNKAIISISSEKMQSIVYQNTTYRQDFSLLY
                     IMQQNPIETIFIVASLLICIIGFMAFGLHTRTSMNEKISLELKKHTQLYEMTSEYFFE
                     YDYKQDKLIISMPEKGIETYYGLDKNDKESENGNIENERDKIRKEYNKKFFDVIKSQE
                     NGTTEMYSIMLDDTFHWIRVTSKIIYNDRKIPMYVIGKICNIDSEKEEKNRLLDKAQR
                     DSLTNIYNAAYIRKLTSQNLLNLSTEKNGALLIIDIDYFKSINDTYGHLLGDKVLIDV
                     AKALDESFAKNDIVGRLGGDEFSVYINDIINKEELINKCNDVYNHIHLIKLPNGESLS
                     ISMGVVIAKPGQEYDELYQIADNALYDSKRQGRNRFKIV"
     gene            complement(10770..11591)
                     /locus_tag="KR294_002497"
     CDS             complement(10770..11591)
                     /locus_tag="KR294_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBH0240567.1"
                     /translation="MIDINLEKCVGCGMCESDCLVNAIKVKDDKAKVKNILCINCGHC
                     MAICPTDAIEMQGFDKNEVIEYNRESFELEPEKLLNFIKFRRSIRQYKDIEVEEEKIK
                     NIVEAGRYTPTGGNRQPIRYILVKEKLKEVKELAIQGLYNLALDTDDNDPVRSIYKNT
                     FKKMYKRYKENGNDSLFYDAPLLMVVVGDMSLGGSAYVDGGLAASNMELMAYSQGLGI
                     CYNGFFVMASNVEPKIKELLGMSENEAVITSFILGYPDVKYKRTVNRNTAKFEVR"
     gene            complement(12109..12585)
                     /locus_tag="KR294_002498"
     CDS             complement(12109..12585)
                     /locus_tag="KR294_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HBH0240568.1"
                     /translation="MKLTTICYIEKDDKTLMLYRNKKKDDIHEGKYVGVGGKFEQGET
                     PEECVIREVKEETGLTLKSLSYKGLITFPKFKDEEDWYMFLYFSDEFEGELSEKDLND
                     CKEGNLIWVDNDKIFDLNMWEGDRLFLNWAKTGNIFSAKIVYDNGKLKDYNVSFLD"
     gene            complement(12620..13198)
                     /locus_tag="KR294_002499"
     CDS             complement(12620..13198)
                     /locus_tag="KR294_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBH0240569.1"
                     /translation="MREEALEILFKYLETDRMRKHCYAVEAVMRELAKRLEPEKEEEW
                     AVAGLLHDLDSDIVGRKPGEICEGHATTTVELLKKENFGNEEMYRAILGHHDGMGVTR
                     TSLMEKAIYAADPITGFITAIALVYPDKKLTSVKTKSVIKRMKETRFASNVNRDAMRS
                     IEDIGIPFDEFAELSLNAMKNISDVLESAENN"
     gene            complement(13302..15902)
                     /locus_tag="KR294_002500"
     CDS             complement(13302..15902)
                     /locus_tag="KR294_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HBH0240570.1"
                     /translation="MKKIELLAPVGSFDSLKAAVQNGANAVYLGGKDFSARASANNFD
                     RNELIEAVKYSHIRGVQVFVTVNTLIKQYEIEDFVEYVKFLYDIDIDALIVQDIGMAR
                     LIKKLLPDFELHASTQMVAHSLEDVKYLQSVGFDRVVLARELNVDEIKWICENTTVDI
                     EVFVHGALCVCYSGQCLMSSMIGNRSGNRGRCAQPCRQKYELIDINTGEVVKSNGDYL
                     LSPRDLSTIEDLDKIIEAGVLSLKIEGRMKKPEYVATVVSGYREAINEFVDKKKISIS
                     EEIINNLYTIFNRKFTKGYILGEVGKDIMNSNRPNNQGLYIGKVLDYNRKNKRLRVML
                     ENTLKKGDGINLGGGTIGRIIKDGEITTIAHKGDLIELDFVGEAKRNQLIYKTSDSEL
                     MDRVQATFQQDKEFIKTNIRAKVSIKLGKKPELFISDFCGNKSVVEGDKIVEKAIKVA
                     LSKEKIETQIQKLGNTPYKLKEIEIDLDEGVSMPISVLNQMRRDCIELLDEERIKIKD
                     RKFKKNRLKYQPNRVNKQKKLDTAPKIRVKVKNLEQLEAVLNYNVDLIYYEDINTLSK
                     ALQMVSSISIDSNISIDSSISMDLDTSSSLGTPKELMGSNTNNIDTLSNTSKIDTLNK
                     NHSNTAVTDKKLIYSAPRIVRNKEYKQFEILDNIKGINKVQIGNWGSMEYFKKKDLNI
                     DCYLNVFNSESINHFKEEGASTVCLSQELNLNEIKQTLKYTDVEIEAVIYGYAPMMVT
                     EYCPMGVVVRDCKKDKRVAKCKESSYALRDFTDASYRITQDIFCRSTIYNSKVTCMLD
                     NLYELEEIGIDVFRIDFTVEDSEMVKKVIEAHIEVLSNNYKLGKKATDLYKKLDEIGT
                     VAGHYYKGVE"
     gene            complement(16394..17077)
                     /locus_tag="KR294_002501"
     CDS             complement(16394..17077)
                     /locus_tag="KR294_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HBH0240571.1"
                     /translation="MTSKSQMSESFFLCSLLAITGGFLDIYTYVVRGKVFANAQTGNI
                     VLFGLNIAEGNVKESFYYLIPILAFMLGVFIAEKIRKYFTNNKTKIHWRQVIIIIEMI
                     TILIVSFIPRGRFNMFVNVAISFICSMQVESFRKVNGNSFATTMCTGNLRSATETLFH
                     YIHTKNIFMIKKSLQYYAVIIFFISGAILGTFFTKIFVEKSILICFFILAVVFGIMFI
                     NKDDSFNEN"
     gene            complement(17253..17843)
                     /gene="zapA"
                     /locus_tag="KR294_002502"
     CDS             complement(17253..17843)
                     /gene="zapA"
                     /locus_tag="KR294_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HBH0240572.1"
                     /translation="MNKVMVKIHGAEYPMVGDKSEKFMISIADFVDKEMDKITRQNPK
                     LSLSVAAILTALNISDLLFECSDENEKLIKANEELSKKVGASNEELQLEIKSLKLTIA
                     EKEAENREAETKMKELIEIIENKKQEIFELSNTTEGSRAELDAYKNKIEELSTQLEEA
                     NERATIAENLASEFQNKAYDLQLKCTGLNNDAKNVE"
     gene            complement(17868..20261)
                     /locus_tag="KR294_002503"
     CDS             complement(17868..20261)
                     /locus_tag="KR294_002503"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HBH0240573.1"
                     /translation="MLVSLKWLRDYVDIDMDVKEFADKMTMTGTKVETIDYYGEEIEN
                     ILVGKILEIKQHPNADKLVVTKVDIGDKVVQIVTGATNISEGDYIPVAVNGSKLPGGV
                     EIKQTDFRGELSDGMMCSAAELGIDEHYIEEYKRGGIYILDHEDSYELGKDIKDVLGL
                     KDALIDFELTSNRPDCKCMMGIAREAAATIGTKVKYPEIEVKESDEEIDFKVEIDNPD
                     LCRRYVARMVTDVKIEPSPYWMQRRLTEAGVRPISNIVDITNFVMLELGQPLHAFDIN
                     QVETGRIVVRNAKDGEKLVTLDDVERTLDKDMLVITNGEKSLGLAGVMGGANSEITSN
                     TKTVLFESANFKPENIRMTAKKVGIRSEASSRNEKDLDPNLAEIAANRAAQLVEMLGA
                     GKVLKGVVDVYPNKPEPKKLVVNPQRINHLLGVDVPMEQFVGILESLEFKCNLVANDK
                     LEIDVPSFRTDMEQEADVWEEIARIYGFENIPSVQLEGNTTAGIKTSKQKFMDALKDN
                     STAVGLNEILTYSFVSPKGVDKIRVPEGNAKRNFVKLLNPLGEETSVMRTTLIPNMLD
                     VLSTNVSHKIEEVSAFECGHIFIPQDSELPKEENRMCVGMYGKDVDFFALKGTIETIL
                     VNVGFKGYEIEPQDNNTTFHPGRCAKIVYNNKYVGTLGELHPDVIENYNLGQRVYVAE
                     IDIDFVFDNSDRTKNYVPLPKYPSTSRDIALIVKDDVFVKQIEDIIKENGQGLVESYK
                     LFDVYKGSQIEAGYKSIAYSITYRSKDKTLTDEDVAKVHDKILSELSEKLNANLRSN"
     gene            complement(20278..21297)
                     /gene="pheS"
                     /locus_tag="KR294_002504"
     CDS             complement(20278..21297)
                     /gene="pheS"
                     /locus_tag="KR294_002504"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HBH0240574.1"
                     /translation="MQEKLLALREAALAEIKEAQSIESVESLRVKYLGKKGEITAILK
                     EMGKLSAEERPVVGKVANEVRENIELSINSKKEEINAIEKERKLKEEVIDVTQPGKVL
                     KVGKKHPITQIIDEVTDIFIGMGFSIAEGPEVETVENNFDALNAPKDHPSRDMSDTFY
                     INDGVLLRTQTSPVQVRTMRSQELPIKVIAPGRCFRSDSPDATHSPMFHQIEGLVVGK
                     DVTMAEFKGTMDIFVEKLFGSDIKTKFRPHNFPFTEPSAEVDVTCFKCGGKGCPMCKY
                     EGWIEILGSGMVHPNVLRNCGIDPEVYSGFAFGVGVERLAMLKYEIDDIRLLFENDMR
                     FLNQF"
     misc_binding    complement(21347..21581)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
BASE COUNT         6666 a         3989 c         2387 g         8677 t
ORIGIN      
        1 ataactgtta tttgattaaa tatagggtct actatagtat taccttcttc aagtcttata
       61 agacttcttg ggtctatgct tttattatat gccttaactc caattttata ttttctcaat
      121 ttaacaacat attcggacat agaaaaaata aaatctatat tatcttcatt taatttacta
      181 tcttcaccca aaatggataa tatagatttt tttatgctat taattccttc attttctaca
      241 gttctatctt ccatatatac atcatataga acatttaaaa catttaataa aatactttct
      301 tcatcataat cttcagattt caaatcaatg tacttatcaa ttaattgtat tgctttaatc
      361 cttgccatct gaaactttac aacatctgat ttgtctaatt ctatagaaaa tcctattatc
      421 ttgtctttaa tactctgtag taattcgaca tactctattt tactattatt tataagattg
      481 tgcataatgg aattatacac cacagaacct aataaataat caaataaaag ttcttctttt
      541 ttaaaataaa taacatactt ttttattagt ttaataacct catcttcact tttttgaata
      601 ttagtatttg ataaaattag tggtaataaa atatttaaaa aattgatatt tcctattttt
      661 tctccataaa atctatagta aataagttca tctctcagtc tattttcgtc tatatacaca
      721 catctttgcg ttttatcatc tattaaggat tttgtattta ttatagttaa atctttaaga
      781 gccctacttg cactactaaa agaagatgtg tagacttttt ttagtaattc gtcattcata
      841 aatatatcct ttctgaaaaa ttgaatgtaa ataaattgtt attaaaaaaa aagagacagc
      901 ccgtttaaga agctgtcata tataggggga tagtagtgta caaaaatcat tgtaatctac
      961 tatctatata ttattatacg atactacttt tttatatgta aagcatcagt tttcgacatc
     1021 cctatatttt acagttatac aaattgcgta ctaagttcaa ttttattctt tttatttcaa
     1081 cattttatca tgctacattc tttcaggagc gtgcattccc aacaatttca gagaattttc
     1141 taaagtttgt tttgttgcta aaactaatgc aagtcttgct tttcttattt ccaaattttc
     1201 tactaaaatt ggattgtcat gataaaattt attaaacgct tgagctaaat ctagcataaa
     1261 tctagtcact atatgtggct catttttctt tagagcaagt aaaatattct tattgaatga
     1321 ttctataact ctaagaactt ctgcactatc ttcatcagct aatagactat aatctatatc
     1381 agaagtcact tctacttctg cttttcttaa aactgcacag catctagcat gtgtatactg
     1441 aacatatggt ccagtctcac catcaaaact aagcgttctt tcccaagaga aggtatagtc
     1501 tttaattcta ctattagata actcttggaa tactactgcc ccaacaccta cttgcttaga
     1561 tatttcatcc acatttttag catttgggtt tttagctagt ataatttcct tagttttatc
     1621 tatagcttga tttaaagcat cttctaaaaa tactactctt ccttttctag tcgacatagt
     1681 accttcttca agtgcaacca taccaaatcc aacatgaatt aaatcttttg cccaatcata
     1741 tcccataagc tcaattacct taaaccattg ttggaaatgt aagttttgtt gagaaccaac
     1801 tacatatata cacttgtcaa aatcataagt ttcttttcta tatattgcag cagctaaatc
     1861 tcttgtcata tataacgttg aaccatcatt cttagtaata agtgctggtg gcattttata
     1921 ctcttctaaa tcaacaattc ttgctccttt agactctttt aaaagatttt tctcttctaa
     1981 tagttcgata actctgttca ttttatcaga ataaaaactc tctcctgcta aagaatcaaa
     2041 ttctatatct aaaagtttat aaactctgtt aaactctttt aaactctcat ttctaaacca
     2101 ttgccataat tcttgtgctt cttcgtcacc attttctaat ttattaaacc atgctcttgc
     2161 ttcatcttcc atttctgggt gttgttcagc ttcatcatgg aatcttacgt ataattttag
     2221 taattctgga attggattag actctactac ttctttttct ccccactttt taaaggccac
     2281 tattaactta ccaaactgag ttccatagtc acctaaatga tttattctta tagtcttgta
     2341 tccttgcgaa tcatatatct tatataaagc attacctata actgtagttc ttatgtgccc
     2401 tatatggaaa ggttttgcta tatttggaga agaatattca actattacag ttttatcttt
     2461 tccaaaatca ctatgtccgt aattttcttt ttcatctaaa acttttttaa ttacagtttc
     2521 tgctaattga gatttattta caaagaaatt tacatatccg cctaattgta ttacttttgt
     2581 tatctctcca cttggttcta tactttccgc caattcactt gctatcatgt ttggagcttt
     2641 tctaaacact ttggctaatt taaagcatgg aaaagcatag tcccccatat ccttatttgg
     2701 tggaacttct ataagtgcct ctatctcttc tttcgataaa tcttctattt tttctttaag
     2761 gcaatttgat attgccacct taaaatcttg cattctgttg ctcctctcta cattgttcct
     2821 ggtttatatt gtgcttatct ctttatgtta aatcaaattt cgtgtttttt caagtatttc
     2881 attacagtgt aaaacacttt agtaattatg ttttctgtat atattaaaaa tactataatt
     2941 tcagttttta atcacactat tattgatttt ttataagact tttttctatt ttattgtttc
     3001 ttgtactatc cagttgactt tatatacttt ttttaatctt ttatctgttt tcatacatca
     3061 atgtcagctt tatatacatt tttttaatct tttatctatt ttcatacatc aatgtcagct
     3121 ttatatactt tttttacttt tttatctatt tttatacatc aatattagct ttatatactt
     3181 tttttactct tttatctatt ttctataaat ctttttcact cttaactttt attccttctt
     3241 cttctaatag ccttgctgtt atacctttcc ctggtatctt tttacctgaa aaactaccat
     3301 catatattag attacatcca caagaggggc taccctcttt tagtattgct tcgctacata
     3361 catataaatt tgctattttt agagtttcat tagcccctct tacaaagttt tctgttacat
     3421 ccttattatc tttagtaatt acttttccat caactatctc agcaggtggt cttggtgtag
     3481 atagaccacc taactgctct gggcatacaa gtgtaaattc tttgcctttt aaatattcct
     3541 tgactttttc attatcatta ttatcgccac tatatttaca atttattcct attaaacatg
     3601 cagataccaa tatcataaaa atgtgctcct atacaaatta tatatattct catacaaatt
     3661 actaatgtat tcttatacaa attattttaa tttaacaatt gttactcctg ctccaccttc
     3721 tccatattga ccacctcttt gtgattttac atgtctattt cttcttaaaa tgtcttgtag
     3781 ccctgctttt aatactcctg tacctattcc atgtattact gttacagact ctaaacctgc
     3841 cacatatgca tcatcaagat acttttctac ttccattata gcttcttcta ggtttaaccc
     3901 tctaaggtca acttcatttt ttacactacc agattttgac cttataatgt ttctcgttga
     3961 tttagttaca tttgttgaaa catctttgcg tgttttttgt aaagatttaa aaggtagagt
     4021 catcttcatt ataccaattt gcactactgc ttcttttctc tttttatcta ctgaaactac
     4081 actaccattt tgatttaaag ttattacctt aacttcttca cctggcttta agtcttttat
     4141 ctccttattt gatacctttg gaactatcat actttttact gttggctgaa gacttcccat
     4201 agagctagtc aattcttttc taagttcttc tatcttacga ttcttttctt ttgaagctct
     4261 ttcttgttca agacttctaa gttcttttat tataatatct acttcttctt tagcttgtct
     4321 tataattgaa aatgcttctg atttagcttt ttcaatcatc ttatctcttt gactgaccaa
     4381 tttttcaagt ttttcgtcat actctacttt cagtttttca atctcttctt ttaatctttc
     4441 agcttcttct ctatcttcta ctgctttgat tctattcttt tcaacattct gtaacacatc
     4501 ttctaaagct atgttttctg tatttatata ttctttagca cgtgaaatca cataatcact
     4561 tagcccaagt tttctagaaa tctcaaacgc atttgatttt ccgggaacac ctataagtaa
     4621 cttatatgtt gggcttaaag tttctatatc aaattcaact gctgcgtttt ctacacctgg
     4681 tttagtaaga gcataatttt taagctcact atagtgagtg gtagctatac atttagctcc
     4741 tacagaattt atatcttcta atactgctat tgcaagggca gctccttcaa cagggtctgt
     4801 tcctgctcct aactcgtcaa atataactaa agagtctgct gttacgtttt gtaatataga
     4861 tactatattc gtcatatgag atgaaaatgt tgatagactc tgttcaatac tctgctcatc
     4921 tcctatatct gcaaatacat tatcatatac acacatacta cttccataat cagcaggtat
     4981 atgaagtcca ctttgtgtca taagtgcaaa tagacctaca gtttttattg taacagtctt
     5041 accacctgtg tttggacctg ttatcaccaa tgtatggaag tctcttccta aataaatggt
     5101 atttgctact accttctttt tatccagcag tggatgtctt ccatttttta tgtttaaata
     5161 tttatcctca tttaaagttg gttctattcc tctcatctgt atagaaagtt ttccctttga
     5221 aaatgcaaag tccaatcttc caagtatctc ttgattagag attaaatctt cgctcacttc
     5281 tccaaccata gcagaaagct ctgataaaat tctttctatt tcttcttgct cacctagttt
     5341 taactgtctc aattcattgt tcatctctac tatagtcatt ggctctataa aaagtgtcgc
     5401 accagaagat gactggtcat gcactatacc agctacttgc gacctatatt cagattttac
     5461 aggtactaca aatctatcac ctcttagaga aattattgca tcttgtaagt acttttgata
     5521 agtagttgaa cttattattg aatttaattt tgacctaatg gattgatttt tttgggctat
     5581 tcttcttctg atatctctaa gtgtacttga agcattgtca gatatttcta cttcactaat
     5641 tatagcattg tatatctggt cttctatgtc cttgtataca tatagagaat ttgatagaga
     5701 ttgtattatt ggataattaa aatcttcttc atcactacta gataagctat ttcttaatct
     5761 tctagccact cttaaggtat ctgctatcat aatcagactt cctgggtcaa gagaagcacc
     5821 tatataagct ctctttacct tatcttctat atcatgaata ccttccaacc ctactgaacc
     5881 tctctttata ataattgatt gagcttcact agtttcttct agcatagatt tcacttctac
     5941 aaaatcagta tttggtacta aattttctat atattttaga cctaaagaag atgaggcttt
     6001 cttctttaac aaatctatta ttttattgta ttctagaact cttaacgatt tctcattcat
     6061 tttctatatt caccatcctc gatattttaa cttttttatt taattttaaa aatgtatgtt
     6121 ttcaagcatt tccaataaaa actgcaagtt ttatttcttt ttcatttcta aaattattat
     6181 attttttctc ttttagatat attttacaca tattttgtat tatactatgt atgtagctat
     6241 ctatatatta tacataaaca tgctttattt gtaatataat ctgttaaaaa atcttcttta
     6301 atatttttaa aggagtttat tttagcttat aaaaaaaaat agctacttat atagataaat
     6361 taaggaggaa catgagtcat gggaaacgta ttagaaggat taaaaccaga aagtgttttt
     6421 aaaaactttg agaaaatatc tcaaattcct agaggttctg gaaatgaaaa aggcataagt
     6481 gattttttac ttagctttgg taaaaattta ggtcttgaaa ctattcagga tgaaagctta
     6541 aacataataa taagaaagcc tgctacaaaa ggatatgaaa attgtccagg tgtagttctt
     6601 caaggacata tggatatggt ttgcgaaaaa gaaaagaatg ttgaacatga ttttcttaaa
     6661 gaccctataa aattaagaat tgatggtgac atgatatatg ctactggaac tactctagga
     6721 gctgacaatg gtatagctgt tgctatgggt atggctatat tagaagataa tactttagag
     6781 catcctgcac tagaagtttt agttactgtt aatgaagaag atggtatgaa tggtgcagat
     6841 gcactagacc ctagcttaat taaaggtcaa tatatcctaa atatggactc cgaggaggaa
     6901 ggatacttat tagttagctg tgctggtggt aaaacttgtg ttgttagttt acctgttgaa
     6961 tacaaggaag ttaaaggtga caaacaagga ttattagttg aggttactgg actattaggt
     7021 ggacactctg gtatggaaat tgttttacaa agagcaaatg ctaacaaagc aatagctaga
     7081 gtattaagtg tattgaatgt tgattatgaa ttagcttctg ttgatggtgg tactaagcac
     7141 aatgctatac ctcgtgaagc taaatgtgta atagctgtta ataaagctga tgttgaatct
     7201 gctaaaaaac aaataaatga cattttaact gcatttaaac atgagtttac tacttctgac
     7261 cctggcatga cttactcagt agctgaaact tctgtagaca aagttcttac taaagattgt
     7321 aaagaaaaag ttgttcaaat gtcttgctta actcctcatg gagttcaatc agtaagtctt
     7381 gatatagaag gattagttga aagttctact aacttcgcta taatcgaaac taaagaatct
     7441 actattgaat ttttaacttc tgttagaagt tctgttatgt ctattagaga tgaaatcgct
     7501 gatagaataa gacttttggc tcaagcttta ggtgctaatt acgaccttat agctcaatac
     7561 ccagcttggg aatttaaaaa aggctcaaaa ttagaaaaaa tatgcagtga aacttatgag
     7621 aaattaactg gtaaagttcc tactgttatg gctctacatg ctggtcttga gtgtggatta
     7681 ttacttgata aacttcctca tgctgaagct atctctatag gaccagatat gtttgatgtt
     7741 catactccaa atgaacatgt tagtatccct tctgtagcta atgtttggga ttatgttatt
     7801 gaaatattaa aatctatgaa ccaatattaa atttaagttt tgattctaag tagattttaa
     7861 ttttaagtaa tctatataaa attaactctg taaattaata ctacggttag tataatattt
     7921 actttcaata ttaacttata gaaataaagc ctaatgatag ataataacat gtatcattag
     7981 gctttattgt aatttaaata ttattaagct ttattctgtt ttaaaattaa ttcttatact
     8041 attttaaatc tatttcttcc ttgtctctta gaatcataaa gagcattatc tgctatttga
     8101 tacagttcat catactcttg accaggcttt gctataacta cccccatact aatagataaa
     8161 ctttctccat ttggcaactt aatgagatga atatgattgt atacatcatt acatttatta
     8221 ataagttctt ccttatttat tatatcattg atataaacac taaattcatc tccacccaaa
     8281 cgacctacta tatcattttt tgcaaaactt tcatcaagtg cctttgcaac atcaataagt
     8341 actttatctc ctaacaagtg accataagta tcattaatcg atttaaaata atcaatatct
     8401 ataatcaata aagcaccatt tttttcagtt gataaattca acaaattttg tgaagttaat
     8461 tttctaatat atgctgcatt ataaatattg gttaaactat ccctttgagc cttatctaac
     8521 aatctattct tttcctcttt ttcagaatca atattacata ttttcccgat tacatacatt
     8581 ggtatttttc tatcattata aattattttt gaagtaactc taatccaatg aaaagtatca
     8641 tcaagcataa tagaatacat ttcagttgtt ccattttctt gtgattttat tacatcaaaa
     8701 aactttttat tatattcttt ccttatttta tctctttcat tttctatatt gccattttca
     8761 ctttccttat catttttatc caaaccataa taagtctcaa tacccttttc tggcatagaa
     8821 attatcaatt tatcttgctt ataatcatac tcaaaaaagt attcacttgt catttcatac
     8881 aactgagtat gttttttgag ttctaaagat atcttctcgt tcatacttgt acgagtatgt
     8941 aaaccaaatg ccataaatcc aataatacaa attaataaac tggctacaat aaaaatagtc
     9001 tcaattggat tctgttgcat aatataaagc aacgagaaat cttgtctata tgtagtattt
     9061 tggtagacaa ttgattgcat tttttctgat gaaatactta taatagcttt attaaatata
     9121 ttcaataatt cttgtttatc ttttttaatt ataccaaaac aaatactctt tgctttatag
     9181 gtttgaggaa ctagacgcac atttttatac ttaggttgat tcatatagta ctgcatagaa
     9241 taaccttcgc cataagtgta atctgcatag cctttattaa cagcttctat acactcttct
     9301 aaattatcat accaaactat attctcttca aactgaccat aataattaat acctttggct
     9361 agagctacac gttttccatc taaactattc tcatttaatt tattattaat catcatagta
     9421 tattgagtag aaagaaaagg ccgagacata gctatattat gttcacgaga gtattcataa
     9481 tcataaatca ttcctgctac aatatcaatt tcacgctttt tagtcatgtt ttctaaatct
     9541 tcttgagatt ttacaggcac aagttcaaat tctaagcctg ttttatcaca tatatgattt
     9601 aacaaatcaa ttgatatacc tcttaattca cctgtatctt tatctatatt ttgaaatggt
     9661 ggtttgttta aaagtactcc tacttttaat ttttctgtct ctttaatgta attagtttct
     9721 tcatcagata aaaacatttg attattctct ggtgtaaagt atttttcata taaagtagtt
     9781 gaaaaatatg ggtctttctg ttcaatatta ttaattgctg agttaagctt ttgagttaaa
     9841 tttgtactac ctttaggagt aatgaaataa aatggttttg atgaaaattt tgctacagta
     9901 cgtacacctt ctattgggtt catactcaca ttaagaagta catctgcttt accactcttt
     9961 agtgcttcta gttgctcatc atttgtttta caatatacca attcaggtga cataagattc
    10021 attttacaat actcatctaa ttctttaagt ctagtatcag aattttctat tacagcaata
    10081 cggatttttt tcacatcttg tgaactcatt atgttatcaa tatctgtatt ttcatataat
    10141 gcttgtagta ctgtatttgc tactccataa ttattccctg cataattata tattttttgc
    10201 attggttcat tgtataacat acctcccatt atatcaattt caccattttc taacatcttc
    10261 attaattttg taatagattc atttatctct ccaggaactt gaacaaattc ataattccat
    10321 ccagtatact gtgcaatttc tagtaaatat tcatatgtat acccaaaata gttaccttgc
    10381 tcatctattt cagttaaacc tttttgaata ggataagcaa cacgaatggt acgattatca
    10441 ttacctatag cgttgatacc aaaagaaaat atgcaagaag tgaatataga tgtaattaca
    10501 ataattaata aaagtaattt ttttaaattc actacacaat cctccatata gttaagattt
    10561 acagtataaa ttactgcata aacttgtaga catgtaaaaa tagattagta tataaaagga
    10621 tatataaatc tacttagaaa tttaaatatc cttaatatat acaatatatt taaattataa
    10681 ctcatttata tgtctattac aacaaattta ccctgctaaa tacctactct atatcccata
    10741 attttacaag ttgtagtgaa gtttaagttc tatctcacct caaatttagc agtgtttcta
    10801 tttacagttc ttttatattt cacatctgga taacccaata taaatgaagt gataactgct
    10861 tcgttctcgc tcattcctaa cagttctttt atctttggct ctacatttga tgccataaca
    10921 aaaaatccat tataacaaat tcctaatcct tgagaatagg ccataagttc catattagat
    10981 gcagccaatc ctccatctac ataagcactt ccacctagag acatatcacc tacaactacc
    11041 ataagtagtg gggcatcata aaataaagaa tcatttccgt tctctttgta tcttttgtac
    11101 attttcttaa atgtattttt atagatagaa cgtacagggt cattgtcatc agtatctaat
    11161 gccaaattat aaagaccttg tattgccagt tctttcactt cttttagctt ttcttttact
    11221 aatatgtatc ttataggctg tctattacca cctgttggtg tgtatctacc agcttccact
    11281 atgtttttta ttttttcttc ttctacctct atatctttat attgtcttat acttcttcta
    11341 aatttaataa aattcaataa cttttcgggt tctaattcaa aactttcacg attgtattct
    11401 attacttcat ttttatcaaa tccttgcatt tctattgcat ctgttgggca aattgccata
    11461 cagtgaccac agttaataca gagaatattt ttaacctttg ctttatcatc cttaactttt
    11521 attgcattta caagacagtc tgattcacac atcccacagc ctacacattt ttctaaattt
    11581 atgtctatca ttccaaatta ttcctccttt taaaaaattt actttagtat aaaacaaata
    11641 gttgtctaag tcaattttta tttttttaac aatatactag ccttaactac actttaatgg
    11701 agaaaaatat acataaattg gaacttaaat tagaacttat tcaaagtaaa agataaaaga
    11761 agtagatgtc taaaagtgaa ctttttagtt aattagatat tctttattgt atgaaatcaa
    11821 gtggatattt atcatttcaa caataaaaaa ggcttacctc tattttggat atgtccctgt
    11881 caagtagaca gactaaaaaa aggctatctt tatgcactga gatagcccct tttcccaact
    11941 actattgttt atcttaatat tagtcaataa atttaatttg ctataacctg taagttacat
    12001 tttaatttga tgtaacttta aattacattt ttaagtaata tctttaaatt atattcttaa
    12061 aatatatcat taaactacat tttaattaat ctaaaaacta tatcttaatt aatctaagaa
    12121 acttacatta taatctttta gtttcccatt atcatataca atctttgcac taaagatatt
    12181 tccagtctta gcccaattta agaacagcct gtcaccttcc cacatattta aatcgaatat
    12241 tttatcatta tcaacccaaa ttaaatttcc ttctttacaa tcatttaaat ctttttcaga
    12301 taattcacct tcaaactcat ctgagaaata caaaaacata taccaatctt cttcatcttt
    12361 aaattttgga aaagttatca accctttata tgacaatgat ttaagagtaa gaccagtctc
    12421 ttcttttact tctctaatta cacattcttc tggagtctct ccttgctcaa actttcctcc
    12481 aactcctaca tacttacctt catgtatatc atctttcttt ttatttctgt acaacatcaa
    12541 agtcttgtca tctttttcta tataacaaat agttgtaagt ttcatgtatc tcgccttgct
    12601 ttctctttta tattctcaac taattatttt cagcactttc aagcacatca cttatattct
    12661 tcattgcatt aagagaaagc tctgcaaatt catcaaatgg aatccctata tcttctatac
    12721 ttctcattgc atctctattt acatttgaag caaatctcgt ttctttcatt cttttaataa
    12781 cagacttagt ctttacactg gtaagttttt tatctggata aactaaagct atagcagtta
    12841 taaacccagt tatagggtct gctgcatata ttgctttttc cattaggcta gttcttgtaa
    12901 ctcccattcc atcatgatga ccaagtattg ctctatacat ttcttcgtta ccgaagtttt
    12961 cttttttaag cagttctact gttgttgtag catgtccttc acatatttct cctggctttc
    13021 ttccaactat atctgaatcc aaatcatgta aaagacctgc cactgcccac tcttcttctt
    13081 tttctggctc tagtcttttg gctaattctc tcataacagc ttcaacagca taacaatgtt
    13141 ttctcattct atcagtttct aaatacttaa ataaaatttc taaagcttct tctctcattt
    13201 tcaccaatcc ccctgttttt tcacatatat gatattttta tatattaata cacataaatt
    13261 caagctttta tatatattca tgtatatttt tcatgttata tctattctac acctttatag
    13321 tagtgtcctg caactgttcc aatttcatct aatttcttat acaagtctgt agcctttttt
    13381 ccaagtttat aattattact cagtacctca atgtgagctt caataacctt tttaaccatc
    13441 tcactatctt caactgtaaa atctatccta aatacatcta ttccaatttc ctctaactca
    13501 tatagattgt ccaacataca agtaaccttc gaattgtaaa ttgtacttct acagaatata
    13561 tcttgtgtta tcctataact tgcatccgta aagtctctta aagcataact actttcctta
    13621 catttagcaa ctctcttgtc ctttttacaa tctctaacaa ctactcccat aggacagtat
    13681 tctgtaacca tcataggagc atatccatat attactgctt caatttctac atctgtatat
    13741 tttaaagttt gtttaatttc atttaagttt agttcttgtg acaaacaaac tgtacttgct
    13801 ccctcttctt tgaagtgatt tatactttca ctattgaata catttaagta gcaatctata
    13861 tttaagtctt ttttcttaaa gtattccata gagccccagt taccaatttg aaccttatta
    13921 attcctttta tattatccaa tatctcaaat tgcttgtact ctttatttct aacaatcctt
    13981 ggtgctgaat agattaattt tttgtcagtg actgctgtat tagagtggtt cttattcaaa
    14041 gtatctattt tacttgtatt tgacaaagta tctatgttat ttgtatttga acccattagt
    14101 tctttaggag tacctaaaga cgaagaagta tctaaatcca tagaaatact tgaatctata
    14161 gaaatatttg aatctataga gatacttgag accatttgta aagcttttga taatgtattt
    14221 atatcttcat aatagattaa atctacatta taatttaata ctgcttctaa ttgctccaag
    14281 ttcttaactt taactctaat cttaggagct gtatcaagtt ttttctgttt atttactcta
    14341 tttggctggt attttaatct attcttctta aattttctat cttttatctt tattctttct
    14401 tcatctaaaa gctcaataca atcccttctc atttgattta acacacttat aggcatactt
    14461 acaccttcat ccaggtcaat ttctatctct tttaacttat atggtgtatt tccaagcttt
    14521 tgaatttgtg tttctatttt ttctttactt aaagccacct ttatagcttt ttcaactatt
    14581 ttgtctcctt ctaccaccga tttatttcca caaaaatcac ttataaaaag ctctggcttt
    14641 ttacctagtt taatactcac ttttgcacgt atattagttt ttatgaactc tttatcttgc
    14701 tgaaatgtag cttgtactct atccattaat tcgctgtcag aagtcttata tataagctga
    14761 tttctctttg cttctccaac aaaatctaat tctatcaaat cccctttatg tgctattgta
    14821 gttatctctc catcctttat tattcttcca atagtacctc cacctaagtt aattccatca
    14881 cctttcttaa gcgtattttc tagcattact ctaagtcttt tgttctttct attataatct
    14941 aaaacttttc caatatatag cccttgatta ttaggtctat tagagttcat tatatcctta
    15001 ccaacttcac ctaatatata tccttttgta aactttctat taaatatggt atacaaatta
    15061 tttattattt cctcagaaat acttattttt ttcttatcta caaattcatt aatcgcttct
    15121 ctatatcctg aaaccacagt agctacatac tctggctttt tcattctacc ttcaattttt
    15181 aaagataata cacctgcttc aattatttta tccaaatctt ctatagtact taaatctcta
    15241 ggactcaaca aataatctcc attacttttt actacttctc ctgtatttat atctatcaac
    15301 tcatactttt gtctacatgg ctgtgcacac ctacctctat ttccagacct attgcctatc
    15361 atactactca taaggcattg acccgagtaa catacacata aagctccatg tacaaaaact
    15421 tctatatcta cagttgtatt ttcacaaatc cattttatct catcaacatt taattctctt
    15481 gctaaaacaa ctctatcaaa ccctacactc tgaaggtatt ttacatcttc taaggaatgt
    15541 gctaccattt gagtgcttgc atgtagttca aagtcaggta atagtttttt tataagtctt
    15601 gccattccta tatcctgtac tattaaagca tcaatatcta tatcgtataa aaattttaca
    15661 tactctacaa aatcttctat ttcatactgt tttatcaatg tatttacagt aacaaagact
    15721 tgcactcccc ttatatgaga gtatttaaca gcctcaatca gctcatttct atcaaagtta
    15781 tttgcagatg ctctagcact aaagtcttta ccacctaaat acacagcatt tgctccgttt
    15841 tgaactgctg cttttaatga atcaaaagag cctactggtg caagtaattc tatttttttc
    15901 atatttttct cctctattta tacttgttag gttaatataa ttatatctat aacttaaata
    15961 tttgtattaa atttatatat ttcttactat attttaaatt cttcaatcaa tttatatatt
    16021 agttatttat atttggttca tttgagttaa catatacatt atttactata tttagtatat
    16081 ttctattaac ttatatattg attactgtat tttaaattct tcaattaatt tatatactgc
    16141 ttactaaatt taaaacattt taattaattt gtacactgtt tactatactt gaaatacttc
    16201 tattaatcta tatattgcct actatactta agacatttta attaatttat acactgctta
    16261 ctatacttaa aatacttcta ttaacttata cattgcttac tatattttaa attctttaat
    16321 taatctatgc aatatttgct atatataaag tatatcaaat aacagcttca tttttttgta
    16381 aatttacaga aagttaattt tcattaaatg aatcatcttt attgataaac ataattccaa
    16441 agaccactgc caaaataaaa aaacatatta gtattgattt ttccacgaaa atttttgtaa
    16501 aaaaagttcc taaaatagct ccagatataa agaatataat aacagcataa tactgtaaac
    16561 tcttttttat cataaaaata ttcttagtat gtatataatg aaataaagtt tctgtagcac
    16621 ttcttaaatt tccagtacac attgtcgttg caaaactatt cccatttact tttctaaaac
    16681 tctctacttg cattgaacaa ataaaagaaa tagcaacatt tacaaacata ttaaatcttc
    16741 ctctaggaat aaatgaaaca ataagtattg taatcatttc aattataatg ataacctgac
    16801 gccaatgaat ctttgtctta ttatttgtaa aatactttct tatcttctcg gctataaata
    16861 cacctaacat aaatgccaaa ataggaatca aataataaaa tgattccttt acattacctt
    16921 ctgctatatt aagcccaaac aaaactatat ttccagtttg tgcattagca aagactttac
    16981 ctcttaccac ataagtataa atatccaaaa atcctcctgt tattgccaac aaagaacata
    17041 aaaagaatga ttcagacatc tgactcttgc ttgtcatata taaacctctc gctttctaat
    17101 gatagataca aaatcaaaat cattttagat tctatttttc attgatataa aaaaattatt
    17161 tatatttaaa tattgtctat atttatacat catttatatt tatacattaa aagaagctgt
    17221 ctcaaaaaac aagagacagc aaatctttta gtttattcca cattttttgc atcattattt
    17281 aaccctgtac attttaactg taaatcataa gctttgtttt gaaactcaga agctaagttt
    17341 tcagctatag tagctctttc atttgcttct tcaagttgag tacttaactc ctcaatcttg
    17401 tttttataag catctaactc tgctctagaa ccttctgtcg tattactaag ttcgaatatt
    17461 tcttgctttt tattttctat aatctcaatt aactctttca tcttagtttc agcttcacga
    17521 ttttctgctt ctttttctgc tatcgtaagc tttaaagact tgatttctaa ttgaagctct
    17581 tcattagatg ctccaacctt cttactcaat tcttcattag ctttaatcaa cttctcattc
    17641 tcatctgaac attcaaataa aaggtctgat atatttaatg cagttaatat cgcagcaact
    17701 gataagctca atttcgggtt ttgacgtgtt attttatcca tttctttgtc tacaaaatca
    17761 gcaatactaa tcataaactt ctctgatttg tctccaacca ttggatattc agcgccatgg
    17821 attttaacca ttactttgtt catcctaacc tcccccgaca ttagttgtta atttgatctt
    17881 aagttagcat ttaatttttc gcttaattca cttaatatct tatcatgcac cttagctaca
    17941 tcttcatctg ttagagtttt atctttactt ctataagtta ttgaatatgc aattgacttg
    18001 tatccagctt ctatttgaga acctttgtaa acatcaaata acttgtagct ttctactaat
    18061 ccttgaccat tttcctttat tatatcttct atttgtttta caaatacatc atctttaaca
    18121 ataagagcta tatctcttga tgtagatgga tattttggta atggcacata attctttgtt
    18181 ctatcagaat tatcaaatac aaagtcaata tctatttcag cgacataaac tctttgacct
    18241 agattgtagt tttctataac atctggatgc aattcaccta atgtacctac atatttatta
    18301 ttatacacta ttttagcaca tctaccaggg tggaaggtag tattattatc ttgaggttca
    18361 atttcataac ctttaaatcc gacatttaca agtatagttt ctatagttcc ttttagtgca
    18421 aagaagtcaa catctttacc atacatacct acacacattc tattttcttc cttaggtaat
    18481 tctgaatctt gtgggatgaa tatatgtcca cactcaaatg cagatacttc ttctatttta
    18541 tgagatacat tagttgataa aacatctaac atatttggta ttaaagtagt tctcattaca
    18601 gaagtttctt ctcctaatgg gttaagtaat ttaacaaaat ttctctttgc attaccttct
    18661 ggtactctta tcttatctac tcccttaggg cttacaaatg aatatgttaa tatttcattt
    18721 aatcctacag cagttgaatt atcttttaaa gcatccatga atttttgttt tgaagtttta
    18781 attcctgctg tcgtatttcc ttctaattgt acagaaggta tattctcaaa tccataaatt
    18841 ctagctattt cttcccatac atcagcttct tgttccatat ctgttctaaa gcttggtaca
    18901 tctatttcta atttatcatt agctaccaaa ttacatttaa actctaatga ttctaaaatt
    18961 cctacaaact gctccattgg tacatctaca cctaatagat ggttaattct ttgaggattt
    19021 actaccaatt ttttaggttc tggtttattt ggatatacat ctacaacacc ttttaaaact
    19081 tttcctgctc ctaacatttc aacaagctgt gcagctctat ttgctgctat ctctgcaaga
    19141 ttagggtcta agtctttttc atttcttgaa gatgcttctg acctaatacc aactttttta
    19201 gctgtcattc ttatgttttc tggtttgaaa ttggcacttt caaaaagtac agtcttcgta
    19261 ttagaagtta tttctgagtt agcaccaccc attacaccag ctaaaccaag tgatttttct
    19321 ccatttgtta taactagcat atctttgtct aatgttctct caacatcatc taatgttaca
    19381 agtttctctc catctttagc atttcttact actattcttc cagtctctac ttgatttata
    19441 tcaaaagcat gaagtggttg accaagctct aacattacga agtttgttat atcgactatg
    19501 ttacttatag gtcttactcc tgcttctgta agtcttcttt gcatccaata tggagaaggt
    19561 tctattttta catctgtaac cattctagca acatatcttc tacataaatc tggattatct
    19621 atctcaactt tgaaatctat ctcttcgtca ctttctttta cttcgatttc aggatatttt
    19681 acttttgttc ctatagttgc agctgcttct ctagctatac ccatcatgca tttacaatca
    19741 ggtctgtttg aagttaattc aaaatctatt aaagcatctt ttaatcctaa aacatctttt
    19801 atatcttttc ctaattcata agaatcttcg tggtctaaaa tatatatacc acctctttta
    19861 tactcctcaa tgtaatgttc atctatacct agttcagctg ctgaacacat cataccatct
    19921 gataattcac ctctgaaatc agtctgtttg atttcaactc ctccaggtaa cttagaacca
    19981 tttacagcta ctggaatata atctccttct gatatatttg tagctcctgt aactatttga
    20041 acaactttat ctccaatatc tactttggtt acaaccaact tatcagcatt tggatgttgt
    20101 tttatttcta aaatctttcc aaccaatata ttttctattt cttcaccata ataatctatt
    20161 gtttcaactt tagttcctgt cattgtcatt ttatcagcga actcttttac atccatgtct
    20221 atatcaacat agtctctaag ccattttaaa gatactaaca tctacatacc ctcctaatta
    20281 aaattgattt aagaatctca tatcattttc gaataataat ctaatatcat ctatttcgta
    20341 tttaagcatt gcaagtcttt caaccccaac tccaaatgca aatccactgt aaacttctgg
    20401 gtctattcca caatttctaa gcacatttgg atgaaccata cctgaaccta atatttctat
    20461 ccaaccttca tatttacaca ttgggcaacc tttaccacca catttgaaac aagtaacatc
    20521 aacctctgca cttggttctg taaatgggaa gttgtgaggt ctaaacttag ttttgatatc
    20581 agaaccaaac aatttttcaa cgaagatatc catagttcct ttaaattctg ccatagtaac
    20641 atcttttcca acaacaagcc cttctatctg atggaacatt ggtgagtgtg tagcatctgg
    20701 cgagtctgac ctaaaacatc tacctggtgc aattactttt attggtaact cttgacttct
    20761 catagttctt acttgaactg gagatgtttg agttctaagt aataccccat cattgatata
    20821 gaatgtatcg ctcatatctc ttgatggatg gtctttagga gcgtttaatg cgtcaaagtt
    20881 gttttcaaca gtctcaactt ctggcccttc tgctatagag aatcccattc cgataaatat
    20941 atctgttact tcatctataa tttgagttat tggatgcttc ttcccaacct ttaaaacttt
    21001 tcctggttga gtaacatcta tcacttcctc ttttaatttt ctttcttttt caatagcatt
    21061 tatttcttct tttttagaat ttatgctaag ttcaatgttt tctcttacct cattggcaac
    21121 cttaccaact actggtcttt cttcagcaga taatttaccc atttctttaa gtatggcagt
    21181 tatctcacct ttttttccta agtacttaac tcttaaactt tctacacttt ctatgctttg
    21241 tgcttctttt atttcagcca aagctgcttc acgtaaagca agtaattttt cttgcacaca
    21301 tatcaccctt tcgttttttt gtataaaaaa agcccctcaa tccctgtcta gggacgaaag
    21361 gctatagttt cgcggtacca ccctagtagt ttaacaattt aaaaatcatc aaaccacctc
    21421 taacaaactt aacgcgtttt tgacgtcaaa gcctactgta aaatttcagc tctgttactc
    21481 cagagggaac ttctcatgac ctcttagaaa acactcccag cctaggtgtt tatctcttta
    21541 ctaagtttaa tcaaaatact ttcctctttc attgcattta caatattata ttgtttattt
    21601 tagtattata tcatttccat tcaaattatg tgactatttt taatatatat ccaatacata
    21661 attaatttaa ttatttttta tataatatac atctaatgca taattaactc aattatttt
//
LOCUS       DAEPKC010000066        21698 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.066, whole genome shotgun sequence.
ACCESSION   DAEPKC010000066 DAEPKC010000000
VERSION     DAEPKC010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21698)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21698)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21698
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.066"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(<1..239)
                     /locus_tag="KR294_002505"
     CDS             complement(<1..239)
                     /locus_tag="KR294_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240575.1"
                     /translation="MESKGTLSKNKVYILANGLFLVIALLNINLYTVSINMYRIILLW
                     IFGYSIVYISSFKTDEFINILKVGCLVLVFVSILGV"
     gene            complement(387..1178)
                     /locus_tag="KR294_002506"
     CDS             complement(387..1178)
                     /locus_tag="KR294_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011987989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HBH0240576.1"
                     /translation="MKLKKLLSVALVSAIAISAVGCSNKEDKKILVGASSNPHAKILE
                     VAKPLLKEKGYDLEVKIFDDYVLPNTALDEGSLDANFFQHIPFLEETVKEKGYKLTYT
                     SKVHIEPMGFYSEKVKSLDELKDGAVIAVPNDATNGARALKLLAKNKLIEVKDGELIT
                     KKDITKNPKNIVIKEMNAEQLPTVLKDVDGAVINSNYALTANLNPTKDAIVIESSDSP
                     YVNIIACRENNKDSDKIKALSEAMNSKEVKKFIQDEYKGSIVPAF"
     gene            complement(1214..1870)
                     /locus_tag="KR294_002507"
     CDS             complement(1214..1870)
                     /locus_tag="KR294_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0240577.1"
                     /translation="MNSLIDFLTTLFPNALLQTLYMVIVPTIVATILGFILAIILVVT
                     KPDGLKPNSTINSALGFIVNIFRSFPFMILIVAMIPITRLIVGTSIGETAAIVPITIG
                     AAPFIARIIESSLNEVDKGLIEAAKSFGATKRQIVFKVMIKEAMPSIVSGITLSIISI
                     LGYTAMAGAVGAGGLGNIALIYGYQRFDTAVMVYTVIALIILVQIIQGVGNLAYKKLK
                     "
     gene            complement(1863..2828)
                     /locus_tag="KR294_002508"
     CDS             complement(1863..2828)
                     /locus_tag="KR294_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HBH0240578.1"
                     /translation="MISIKNVNKYYGKIQVLKDVSIEIESGEIFGIIGHSGAGKSTLL
                     RCINGLEEYQEGSVLVSDKEVKSLNEKQMRDLRKELGMIFQHFSLLERKTVFDNVALP
                     LECFGYSKAEIKKRVLELLEVVGISEKKNDKPRNLSGGQKQRVAIARALALNPQVLLC
                     DEATSALDPNTTKSILSLLEDINKNLGITIIVVTHQMEVIKQICGRVAIMENGEVLEV
                     GDTEEIFLRNTKGLRKLIGEESIILPKGTNIKILFPKDISNEAIITTMARELNIDVSI
                     IFGKLEQFKDDILGSLIINISDKSGEQVKQYLTSKGIRWEEMINE"
     regulatory      complement(2934..3040)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            complement(3330..4274)
                     /locus_tag="KR294_002509"
     CDS             complement(3330..4274)
                     /locus_tag="KR294_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YafY family transcriptional regulator"
                     /protein_id="HBH0240579.1"
                     /translation="MSRAERLIELMITINAKRSFTAGELAEEFSVSKRTILRDLQVLE
                     SIGFPLYSKVGAAGGYHVLKERILPPIAFSESEVKSIFFAYQSLEYYNDLPFEQETIS
                     VLKKFLNCIPNDIQYNIENIRRKFVFWTPDRHCSTPLLKELFNIVMNESTIKIEYSSK
                     QKNSVRTIVPIGLYAMNGLWYCPAYCIKSASIKEFRVDRIVKILSIENLSSKKYKVLS
                     SIHDYLKNMEVGTDYHIKINLTDEGVKRCETEFLLARGLKILSKGGYIDMYIPKSTLN
                     WVAEYFLTFGKNATIIEPIELKHLVKSKVLELYNHHCI"
     gene            4385..4852
                     /locus_tag="KR294_002510"
     CDS             4385..4852
                     /locus_tag="KR294_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240580.1"
                     /translation="MENNTIKADDIINYCLSNLDDVLLMNSWGERAIYYNPNGILKRG
                     VYVLTIKEKDSNHDKGSLVSRPNVYRVNIGLKKETFIEMFGYIPKRPGVGQIVDMDFD
                     FTKLDTIMPHPIYSWMGWICVLSPTEKTFENFKTLIGESYNFAKQKFKKRKNK"
     gene            complement(5022..5621)
                     /locus_tag="KR294_002511"
     CDS             complement(5022..5621)
                     /locus_tag="KR294_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240581.1"
                     /translation="MKLKRTLFVGLALVLAIGITACTKNNEKPSENTGKNPNESVNNN
                     EGYMNYYSTSYNDYIAGLNRYSIYDTPESINNQFKDKEYPGNEKYLSDVKAAYKDSRD
                     KIQSFVTSLKKDGKTEDTELKKMNDDLIAEGERLVKDIDKRIEKLDKVSDEDMKKGQN
                     DFIKLVHGTEDVGNDIGSGFRKMIKDMNDRLGITGNNKK"
     gene            5867..6463
                     /locus_tag="KR294_002512"
     CDS             5867..6463
                     /locus_tag="KR294_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3793 family protein"
                     /protein_id="HBH0240582.1"
                     /translation="MSCCNSQFCCKNKIESSYIKWLLEVLGPVFLGSKPAEIINISFT
                     DVNREEKINDIYKYLYKCKKIDFIVIDKEKKGLKILFVNKKALSEKLKCKKTVNFLKF
                     LGYKQNTNVNAYLEHLVDKLKSDVFPDEIGIFLGYPLKDVIGFMGYSNYEVSMIKYWK
                     VYGDTKQSEDTYSKFLLHRKKMRKLLDYISVDKIVSCF"
     gene            complement(6561..7520)
                     /locus_tag="KR294_002513"
     CDS             complement(6561..7520)
                     /locus_tag="KR294_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NrtA/SsuA/CpmA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HBH0240583.1"
                     /translation="MTSLIMVLVGTVGCSTTNDKKDEPAKKEASLPKEINLTYVKSPL
                     NVPSILEKKDDLFGKEFKKDNIKVNFHELTTGPEQTQALAAGELDFLHALGGTSAIIA
                     ASNGVGLKITNIYSRSPKGYMLITNNDNIKSIKDLKGKKIVGPKGTILHQLLIAALAK
                     EGYTIDDVEYVNMDIPSAASALESKSADVAMLAGPVALKTINSGAKMIVNGEGLVSGI
                     IVTAVSDDFAEKYPELVKRFMKVHEETLKYMNENKDEVMDVVSKEVGLSLDETKEMYS
                     WYDFSSKITDKDIKELEDTQEFLMSNGMQQKKINIKDMLYNQN"
     gene            complement(7554..8285)
                     /locus_tag="KR294_002514"
     CDS             complement(7554..8285)
                     /locus_tag="KR294_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0240584.1"
                     /translation="MVRSGFLLENIYKKYLVDNKEHLVLDNISLNISSEEITVILGES
                     GCGKTTLLRILAGLENATSGNIYFFNNDKKCTPKVGMVFQESRLMPWLNVSENILLHT
                     EKDNRNKVDLDKYLKMMKLEKFKNSYPNELSGGMAHRVSIARALSFNPDILLMDEPFA
                     ALDYFTRRKMQKEVVNIHKNTKKGVVFVTHNIEEAMEIAKKIIVFSKNKRIKQFSVED
                     EYNRDLTKNYYINLKKEILRELGEF"
     gene            complement(8278..9048)
                     /locus_tag="KR294_002515"
     CDS             complement(8278..9048)
                     /locus_tag="KR294_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0240585.1"
                     /translation="MFEKIHKRLKGYYIFLIILILWKIVCVLGIWSSYILPPPEIVLD
                     TFIKMIYDGSIFLNVYASVRRILIGFLISSLMAIPLGVLFGVNKKMYEYFKPLFEFMR
                     STPPLALVPMLILWFGIGEESKIIIIILASFFPIFLNTLKGIKNCDNKLIEVGKSFNL
                     SKKRIFYKIIIPNSMLDIVVGLSLGLGYSFRAIIGAELIAASSGLGYLISDGKDMSRT
                     DVVLVGIFVIGFLGILSDYLFSKIITKFSKGKQVDLNG"
     gene            complement(9133..9843)
                     /locus_tag="KR294_002516"
     CDS             complement(9133..9843)
                     /locus_tag="KR294_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AIM24 family protein"
                     /protein_id="HBH0240586.1"
                     /translation="MFKFDVTNELMCIARGSGKFFAKKGAMVAFKGNFNFEKLLLGPS
                     NGGGLGRALLGHVQRSLTGEQMPIMVVEGEGEIYLAQNAYHVDVISIDPGDSIYVESE
                     NLLAFSEQLNYSVKLIGSGVISQKGLFTTHLVNKTGQNQDVAIITDGNPLILEGPCCV
                     DPDALVAWTGREPYPKVSKLSWKTFIGQTSGESYHMEFVEPGQIVIIQPSERLSGLKT
                     DSTPSDRMSSGGLRLGID"
     gene            complement(10023..10175)
                     /locus_tag="KR294_002517"
     CDS             complement(10023..10175)
                     /locus_tag="KR294_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HBH0240587.1"
                     /translation="MATFIIAAIVVVLMALAVMYMVKNSKKNGSSCGCGCSGCSSSKS
                     CHSAKR"
     gene            complement(10201..12357)
                     /gene="feoB"
                     /locus_tag="KR294_002518"
     CDS             complement(10201..12357)
                     /gene="feoB"
                     /locus_tag="KR294_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HBH0240588.1"
                     /translation="MSIKIGLIGNPNCGKTTMFNGLTGSSQYVGNWPGVTVEKKGGKL
                     KGNKDVEIVDLPGIYSLSPYTLEEVVTRNFMLDDKPDAVINIVDASNIERNLYLTTQV
                     LELGIPTVIALNMMDIVNKNGDKINIKELSEVIGCPVVEVTAVKGQGIMEAAEKAVEL
                     ASSNNKLNFKLPFVDESKDAIEKIEKIIEEKTPYIDVETRWLAIKLFERDENVIQKLD
                     ISKTILNSIEEITRNCEDELDDDSESIITANRYEFISSIISSIIKKNRKGKETVSDKI
                     DKIVTNRILALPIFALIMWGVYYIAVSSLGTIATDWTNDVLFGEIIQGNVSNFLASLN
                     VAEWLQGLVVDGLIGGVGAVLGFVPQIMLLFLLLSILEDCGYMSRVAFIMDRIFRKFG
                     LSGKSFIPMLISSGCGVPGVMSTRTIENDRDRKMTIMLTTFIPCGAKIPIIALFAGAL
                     FGGASWVAPSMYFLGIAMIIICGIILKKTSLFAGEPSPFVMELPQYHIPSAKGVLIHM
                     WDRGKAFIIKAGTIIFVACGVIWFLQSFNWSLQMVDAGDSILASLGNIVAPIFAPLGF
                     GNWQSSVATVTGLVAKENVVGTFGVLFGISDATEQDPTLLASVASMFTVASAFAFMAF
                     NMLCAPCFAAIGAIKREMGSWKWTWITLGFQTLTAYIIALLINQVGSLVLGTGGSIAG
                     AIISIFIAVAVVFVVLTYSNKNMKKEKMGKLSYMKN"
     gene            complement(12457..12678)
                     /locus_tag="KR294_002519"
     CDS             complement(12457..12678)
                     /locus_tag="KR294_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HBH0240589.1"
                     /translation="MNRLKDIKCGETVKVKKLEGEGATRRRIMDMGITRGVNIFIRKV
                     APLGDPIEVTVRDYELSIRKSDAEKIIVE"
     gene            complement(12691..12903)
                     /locus_tag="KR294_002520"
     CDS             complement(12691..12903)
                     /locus_tag="KR294_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HBH0240590.1"
                     /translation="MMPLILSNTGEEVVIKKISGSDKTRTFLNSIGFVVGTNVKIVSK
                     IDGNLIIDVKDTRVALDKKMASRIII"
     gene            complement(13224..16121)
                     /locus_tag="KR294_002521"
     CDS             complement(13224..16121)
                     /locus_tag="KR294_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBH0240591.1"
                     /translation="MKAFKKHFLILSLIFLLIISCFNNILCFADESENSKKIRVGYCD
                     DYGIISSSKEHSYTGYGYDYLREISKYTRWEYEFVKGSWEECLDRLEKGEIDLLGPLQ
                     KNDERNKLFNFPKLNSGYEYSVLYTKDSNNNMFYEDISSFKGMRVAVLRGNFHNIAFE
                     KYREENNFSVEYIYCNSIDELIESVNEKKADAFVCGSIINAKGMKIVSKFSVEPFYFA
                     TAKYKPNLVKELDYALKELKINDMYYELELYKKYFKREVNNSIAFTRQEMNFIKANPK
                     LTMVYDSEWSPVEYYDKESNSFKGISSNLMSIISKKCGIKFEYIKTKNYNESLDYIKS
                     GKANMLCGSINENDKAKRFNMKLTNPYINIPMIMVGKLDTNLNNDLNIALTSSYKSID
                     SYIEKSFENAKTTSYKSIESCLNAINEGKANLMILSSYQFDELLREGKSENLSVISVL
                     DTSYGMRIGVSNKTDPILVSILNKSIDKITEEELSDCIYSNTIDKPYKVPFGVIFKEY
                     SIQIISFVCILFLIAIKYIIYNKKKKEDYLKKIAYTDPLTGADSIDKFKINSNKLFAK
                     NNPEEYALFYIDVDKFKYINDMFGYDMGNDTLIHISNTIASELKEDEIFARVSADHFV
                     LLIKYKTDDDIKTRLNNIYNKVQILSNPKINYYKLILDCGIYKISKSDNDINTIMDRA
                     NTARKTIKGGHKNSFAFYDKEMHKKILKEKEIENSMVDALNNGEFIVYFQPKYSLSDY
                     QIIGAEALVRWDNPQKGLIPPIEFIPVFERNGFIVNIDFYVFEEVCKKIREWMDEGQK
                     VVPISVNLSRMHFVNSNFIEKFKLIVDKYKIPTRLIELELTETAVLDNIEGLLDTMNN
                     LKEKGFVISMDDFGTGYSSLNLLKELPVDILKLDRAFFTEKDESNNEKIVISNVIKMA
                     KELKMKVISEGVETISQVEFLKQIGCDMVQGYLFSKPMPVKEFEKIAFKKE"
     gene            complement(16448..17056)
                     /locus_tag="KR294_002522"
     CDS             complement(16448..17056)
                     /locus_tag="KR294_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dienelactone hydrolase family protein"
                     /protein_id="HBH0240592.1"
                     /translation="MVDNLIKYIHKSYVAIVVLHEIYGINSFIEDVCQKYYKYGYDVF
                     CPELLGEKRVFPYSKVQEAYDFFINNVGFDIYKKVEKLINDLKSEYKYVFVAGYSVGA
                     TIAWRCSEDSFCDGIICCYGSRIRDYMDVIPKCPTLLVFAKHDSFDVDSISYQLSRKQ
                     NIQIEILDANHGFIDRYSNNYSDIQTKVFTIKEKSFLSKYLA"
     gene            complement(17316..17861)
                     /locus_tag="KR294_002523"
     CDS             complement(17316..17861)
                     /locus_tag="KR294_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH peroxidase"
                     /protein_id="HBH0240593.1"
                     /translation="MKKFVCTVCGYIHEGDAAPAQCPVCKVGADKFEEMKGEKNWADE
                     HRIGVAQGVDEEIIEGLRANFVGECTEVGMYLAMSRQADREGYPEVGEAYKRIALEEA
                     EHAAKFAELLGEVVVADTKENLRVRVDAEYGATDGKLKLAKKAKELGLDAIHDTVHEM
                     CKDEARHGKAFLGLLNRYFGK"
     gene            complement(17979..19802)
                     /locus_tag="KR294_002524"
     CDS             complement(17979..19802)
                     /locus_tag="KR294_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0240594.1"
                     /translation="MNLSTGNQKVSRLKKKEKPKDFKKTFKRIFMYFKKDKKITRFIF
                     LLVIIDSIISTVIPYTIGKVVDIIDIDTYSKSIFLKGIIILLSFYIIEFSVKLSKGIC
                     TARLSQSIVREMRSNLFLKFKNLPITFFDKSSTGDIMSRVTNDVDNISTGISNSLVQL
                     ITGILNILMTFIMMFVLSPILTFCSVILIPIVMFVSNFIAKRTRVFFKQQQVELGKLN
                     AHIEEMISNINVVKSFNYERKSVNDFKEVNDRLLNISLKSQIYTSLLMPIMNVISNIG
                     FATICIIGGILASKDIITIGVIASFLSYVRQFTRPLNELANLFNTLLSAIAGCERVFE
                     IIDEQEEQEVHNMFKSEINDNKDGNLNSHFVKGEIELKDVSFSYDSKKKILDNINLKI
                     KSGTSNAIIGETGSGKTTIINLITNFYHIDEGSIFLDGKDIYSINRNYLRTCFGVVPQ
                     EGYIFNDTVMENIRYGNLEATDEEVIYASKIANAHKFIVKMREGYSTVLSDRGEDLSE
                     GQKQLISIARAVLKNAPILILDEATSNIDIATEAKIQEAINNLTYGKTSIIIAHRLST
                     ISNCDNIIVLENGRIVESGNHKELIKLKGHYYRNILLTQGK"
     gene            complement(19815..21590)
                     /locus_tag="KR294_002525"
     CDS             complement(19815..21590)
                     /locus_tag="KR294_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0240595.1"
                     /translation="MRYFKKYIKKYIVLFLTAVFFLTLEAFCDLAQPTIMAKIIDIGV
                     SNKNLDYILSTGAIMIGITFLGAIFAIIRSVISARVSQHFSYDLRQDVFEKINTYSLK
                     QIDKFGRASLITRITNDINQMQQFVNGMMRVFIKSPIMCIGSLIIAIKLNLKMSIIIL
                     IAVLIIFIIILLNMKIGYRLFKNVQESTDKVNSKLRQFLSGIKVVKLFCRYDYENQSF
                     EELNDELFKNSRKATTMMSFFRPTITIIINVSIIIILLIGRHLIYSGEIKIGIIVAYV
                     NYMTRILTSLIMISHVFNVFVRAKASYERISEVLVDENEEVIEREESLDVGEKDLKFV
                     NCDIIFENVDFSYNKNTDEKILKNVSFKIEEGQNIGVIGQTGSGKTSLVNLIQKLYII
                     DKGDIKIGGRSIYSISEESLRARIGVVFQNSSVFGKSILENVVMGNRDICKEDVVKSC
                     EIANANQFITKLENTYDEVLFQRGKNLSGGQRQRITIARAIAKKPQILILDDCFSAMD
                     INTETIIRKNIKEYISNLREKESKKCTVITISQKISSIIDCDKILVLDEGEVVGFATH
                     EDLLVSSPIYKKIFALQNLVSEDVN"
BASE COUNT         7171 a         3805 c         2173 g         8549 t
ORIGIN      
        1 actcctaaaa tacttacaaa aactaataca agacacccta ctttcaatat atttataaat
       61 tcatctgttt taaagctact tatataaact atagaatatc caaatatcca aagtaaaatt
      121 attctataca tatttataga aactgtatac aaatttatat ttaaaagtgc aataaccaaa
      181 aataacccat tagctagtat atagacctta ttcttactta aagttccttt agattccata
      241 ttccccacca cttcttcatt tttatatagt tttacctata aatatgttac cacaattctt
      301 ccaaaaaatt tgtcactttc tagttataaa aaaaaatgag taaatatttt taattttact
      361 cattttgtag attttgtata ttcagtttaa aaagctggaa ctatacttcc tttatattca
      421 tcttgtataa attttttaac ttctttacta ttcatagcct ctgataaagc cttaatctta
      481 tcactatctt tattattttc tctacaagct attatattta catatggaga atcacttgat
      541 tctattacta ttgcatcctt agtaggattt aagttagctg ttaaagcata attagaattt
      601 attactgctc cgtcaacatc ttttaatact gttggtaatt gctctgcatt catttctttt
      661 attactatat ttttaggatt tttagttata tcttttttag ttataagctc tccatctttt
      721 acttctatca atttattttt tgctaataat ttaagtgctc tagctccatt agttgcatca
      781 tttggcacag ctataacagc tccatctttt aattcatcta atgacttaac tttttctgaa
      841 tagaatccca ttggctctat atgaacttta gatgtataag taagtttata tcctttctcc
      901 ttcacagttt cctctaaaaa tggaatatgt tgaaagaagt tagcatccaa agacccttca
      961 tctaaagctg tatttggaag tacataatca tcaaatattt ttacttctaa atcatatcct
     1021 ttttctttta acaaaggttt tgcaacttcc aatatctttg catgtggatt tgatgaagct
     1081 cctactagta tttttttatc ctctttgttt gaacaaccta ctgctgatat tgctattgct
     1141 gacaccaatg ctactgataa taatttcttt aatttcattt ttactccccc tctttaaaat
     1201 gtttataatt aatttatttt agtttcttat aagccagatt tcctactccc tggattatct
     1261 gaactaatat tataagtgct attacagtat ataccattac tgctgtatca aatctttgat
     1321 atccataaat aagtgctata ttacctaatc ctccagctcc tactgcacct gccatagctg
     1381 tataaccaag tatagatatt attgataatg taattccaga tactattgaa ggcatagctt
     1441 cctttatcat aactttaaat actatttgtc tttttgtagc tccaaaagat tttgctgctt
     1501 ctatcaatcc tttatcaact tcatttaatg agctttctat aattctagcg ataaacggtg
     1561 ctgccccaat agttattggc actattgcag cagtttcccc tatacttgtt ccaacgatta
     1621 atctagttat tggaatcatt gcaactataa gtatcataaa tgggaaactt ctaaatatat
     1681 ttactataaa tcctaatgca ctatttattg tgctatttgg ttttaatcca tctggttttg
     1741 taactactaa tatgattgct aatataaatc ctaatattgt tgccactata gttggtacta
     1801 taaccatata caaagtttgt aacaatgcat ttggaaatag tgttgttaaa aagtcaatta
     1861 aactattcat ttatcatttc ctcccatctt atgcccttac tagttagata ttgttttact
     1921 tgctctccac ttttatctga aatgtttata ataagtgaac ctaaaatatc atctttaaat
     1981 tgttctaatt tcccaaatat tatagacaca tctatattta gttctcttgc catagtcgta
     2041 ataatagctt cattagaaat atctttaggg aatagtatct ttatatttgt tccttttggc
     2101 aatattatac tttcttcacc tattaatttt ctaagtcctt tagtatttct taagaatatt
     2161 tcttctgtat ctcctacctc taatacttct ccattttcca ttattgctac tcttccacaa
     2221 atctgcttta taacttccat ttgatgagtt acaactatta ttgttattcc caaattttta
     2281 tttatatctt caagcaatga aagaattgac tttgtagtat ttgggtctaa tgctgaagtt
     2341 gcttcatcac aaagaagtac ttgtggattt agtgctaaag ctctagcaat tgcaaccctt
     2401 tgtttttgtc cgccacttag atttctgggt ttatcatttt tcttttcaga tattccaact
     2461 acttctaata actctaaaac tcttttttta atttctgcct ttgagtatcc aaaacattct
     2521 aatggcaatg ctacattatc aaatacagtt tttctttcaa gcaatgaaaa gtgttgaaaa
     2581 atcattccta actcttttct taaatctctc atttgctttt cattcaatga ctttacttct
     2641 ttatcagaaa caagtacact gccttcttgg tattcttcta atccgtttat acatctcagt
     2701 agtgttgatt tccctgcacc actatgacct attattccaa aaatttctcc agattctatt
     2761 tcaatactta catctttaag cacttgaatc tttccataat acttattaac attttttatg
     2821 ctaatcataa aatttcctcc catatattct gctcagtttt tatgtttatc ctctcttatg
     2881 tattacaaca aaataaaagc ccgagtataa actcaggctt agaaagctat ttatactcat
     2941 ctatcaacta tattagttgc aggatttagc accaatgtat ataaaatata ctggttgccg
     3001 ggtttcaaag ggccagtccc tccaccactc ttgataagac gttatttaat ttaattctat
     3061 tatcatttgt tgctatgtta tatatgatat attcattaat agtatttgtc aataaattta
     3121 tttaaatttt ttatttttta ttatcgttaa ttaactattt ttaattagtt ttctagctcc
     3181 taacacttta tattttaatg tctatataac tatagaacat cattataaga aataaattaa
     3241 ataacatcaa tctatctaaa tcatctgtaa agtaaattaa gaaaattaac attttatcca
     3301 aactctatcc tactattaaa taaaataatt taaatacaat gatgattata tagctctagt
     3361 actttagact ttaccaaatg tttaagttct ataggttcta ttattgtagc atttttccca
     3421 aaagttaaaa aatattcagc cacccagtta agtgtagatt ttggtatata catatctatg
     3481 tatccacctt tagacaagat tttcaaccct cttgccaaca aaaattctgt ttcacaacgt
     3541 tttactccct catctgtcaa attaatttta atatgataat ctgtacctac ttccatattc
     3601 ttaagataat catgtataga agataaaacc ttatatttct tacttgataa gttttctata
     3661 ctcaaaatct tcacaattct gtctacacga aattccttaa tagatgctga ttttatacag
     3721 taagctggac aataccaaag tccattcatg gcatacaaac caataggaac aatggtacgt
     3781 acactatttt tttgctttga tgaatattca attttaattg tagattcatt cattactata
     3841 ttaaacaatt ctttcaataa tggtgttgaa cagtgcctat ctggtgtcca aaaaacaaat
     3901 ttacgcctta tattctcaat attatattga atatcatttg gtatacaatt taaaaatttt
     3961 tttaaaacag aaatagtttc ttgctcaaat ggcaaatcat tataatattc tagtgactga
     4021 tatgcaaaga atatagattt tacctcactt tctgaaaatg caatcggtgg aagtatacgc
     4081 tctttaagta catgatatcc accagccgct ccaacttttg aatataatgg aaatccaata
     4141 ctctccagca cctgtaagtc tcttaatata gtacgttttg atacagaaaa ttcttctgct
     4201 aattctcctg ctgtaaaact tctttttgca tttattgtta tcatcagttc aattaaacgc
     4261 tcagctcttg acatatttat actcctaatt taaatatagt gacaataatt gtcactatta
     4321 tatgataaga tattcttaca tttaaagcaa taataatagt aaagaaagaa gggactgata
     4381 ctttatggaa aataatacta ttaaggctga tgatattatc aattattgtc tatcaaactt
     4441 agatgatgtt ttattaatga atagttgggg ggaacgagca atttactaca atcctaatgg
     4501 tattttaaag cgaggagtat atgttcttac cattaaagaa aaagacagta atcatgataa
     4561 aggttcgttg gttagtcgcc caaatgtata ccgtgtgaat ataggattaa aaaaagaaac
     4621 ttttattgaa atgtttggat atattccaaa acgtccaggt gtaggtcaaa tagttgatat
     4681 ggattttgat tttacaaaat tggacacaat catgccacat cctatctact catggatggg
     4741 atggatatgc gtcctaagcc ctactgaaaa gacatttgag aactttaaaa ctttaatagg
     4801 agaatcttac aattttgcaa aacaaaaatt taaaaagaga aaaaacaagt aaaaacgtat
     4861 gaaaataatc cctaaataaa ttataataaa aatattaagg ttacaagata aaaattaata
     4921 tcttaataac atgcaaaaaa gcgaagccaa aaaatgtatt atttataagg cttcgctata
     4981 tctcaaataa tttatttcaa atttcaaaac tatttattct attatttctt attatttcct
     5041 gttattccta atctatcatt catatctttt atcatttttc taaaaccact acctatatca
     5101 tttccaacat cttcagttcc atgaactaat tttataaagt cattttgacc ttttttcata
     5161 tcttcatcag ataccttatc taatttttct attctcttat ctatgtcttt tactaatctt
     5221 tccccttcag cgattaggtc atcattcatt ttctttaact ctgtatcttc tgttttacca
     5281 tcttttttaa gagatgttac aaatgattgt attttatctc tactatcttt atatgcagcc
     5341 tttacatcac ttagatattt ttcatttcct ggatattctt tatctttaaa ctgattattt
     5401 atactttctg gagtatcata aatagaatat ctatttagac ctgctatata atcattatag
     5461 cttgttgaat aataattcat atatccttca ttattattta cagattcatt aggatttttt
     5521 cctgtatttt cacttggttt ttcattattt ttagtacatg cagttatacc tatagctaat
     5581 actagtgcta atcctacaaa taaagttctt tttaatttca tttttattac cctcctagat
     5641 gttttatact ataaaaaatt ttaataattt tctttcttaa tttagtattt ctatattttt
     5701 atattttatt tactaaaatt aaacaagtta taatttattt ttttggaaat cataatgaat
     5761 aaataattaa ataaaaaaat tataatttta ttattgatat tgattatcat tcatagtata
     5821 atctaattac ttgatattaa ttttcatttg aaggaggtta tcttttatgt cttgttgtaa
     5881 ttcacaattt tgttgtaaaa ataaaattga atcatcatat ataaaatggc ttttagaagt
     5941 tttaggtcca gtctttttag gctctaaacc tgctgaaata ataaatattt cgtttactga
     6001 tgtaaataga gaggaaaaaa ttaatgatat ttataaatat ctatataaat gtaagaaaat
     6061 agattttata gttattgata aagaaaaaaa gggattaaaa atcttatttg taaataaaaa
     6121 agcattatca gaaaaattaa aatgtaaaaa aacagtaaac tttttaaagt ttttaggata
     6181 caaacaaaat acgaatgtta atgcttattt agagcattta gtagataaac ttaagagtga
     6241 tgtttttcct gatgaaatag gtattttttt aggatatcct cttaaagatg tgattggatt
     6301 tatgggatat agtaattatg aagtttctat gattaaatat tggaaagttt atggtgacac
     6361 aaaacaatcc gaggacacat attcgaagtt tttacttcac cgtaagaaaa tgagaaaatt
     6421 actagactac ataagtgtag ataaaatagt aagctgtttt taattgtatt tttgtataat
     6481 aataaaaata caccctcttt taccatatag tttccataat aaataagggt gtattttcca
     6541 ctttaatatt ttaaagtatt ctaattttga ttgtacaaca tatctttaat atttattttc
     6601 ttttgttgca ttccattaga cattaaaaat tcctgtgtat cttctaattc ttttatatcc
     6661 ttgtccgtta ttttagaact aaagtcatac caagaataca tttcttttgt ttcatctaaa
     6721 gataaaccaa cttctttaga tacaacatcc atcacttcat ccttgttttc attcatatat
     6781 tttaaagttt cttcatgaac cttcataaat ctttttacta attcaggata tttttcagca
     6841 aagtcatcac ttacagcagt aactattatt ccacttacta atccttctcc atttacaatc
     6901 attttggcac ctgaatttat cgttttcaat gccactggac ctgcaagcat tgctacatca
     6961 gcacttttac tttctaatgc agaagcagca ctaggaatat ccatatttac atattcaaca
     7021 tcatctatag tatagccttc tttagcaagt gcagcaatca acagttgatg aagtatagtc
     7081 ccttttggac ctacaatttt tttacctttt aagtctttta tagatttaat attatcatta
     7141 ttagttataa gcatatatcc ttttggtgaa cggctataaa tattcgtaat tttaagacca
     7201 acaccatttg atgcagctat tattgcagac gttcctccta atgcatgtaa aaagtctagc
     7261 tcacctgctg ctaatgcttg agtttgctct ggtcctgttg tcaattcatg gaaattgact
     7321 tttatattgt cctttttaaa ttcctttcca aataaatcat cctttttttc taatatacta
     7381 ggaacattaa gtggtgattt tacataagtt aaatttattt ccttaggtaa actagcctct
     7441 ttttttgcag gttcatcttt cttatcattt gttgttgaac atcctacagt cccaaccaac
     7501 accattatta aagatgtcat tactgctaaa atctttttgt ttcttttaat caattaaaac
     7561 tcccccaatt cccttaatat ttcttttttc aagtttatat aatagttttt agttaaatct
     7621 ctattatatt catcttcgac actaaattgt ttaatccttt tatttttact aaaaacaatt
     7681 attttctttg ctatttccat agcttcttca atattgtgag ttacaaatac tacacctttt
     7741 ttagtatttt tatggatatt tacaacttct ttttgcattt ttcttcttgt gaagtaatct
     7801 agtgctgcaa atggttcgtc catcagcaaa atatcgggat tgaaggaaag tgctcttgct
     7861 atacttactc tgtgagccat tcctcctgat aattcatttg gatatgagtt tttaaacttt
     7921 tcaagcttca tcatttttaa atacttgtct aaatcaactt tatttctatt atctttttca
     7981 gtatgtaaaa gtatattttc acttacattc agccatggca taagtctact ttcttgaaat
     8041 accattccta cttttggagt acacttttta tcattattaa aaaaatatat gtttccacta
     8101 gtagcatttt caagccctgc taaaattcta agtagcgttg ttttcccaca tccactttca
     8161 cctaatataa cagttatctc ttcactagat atatttaaag atatattatc aagaactaaa
     8221 tgctctttat tatcaactaa atatttctta tatatattct ctagcaaaaa tccacttcta
     8281 accatttaaa tcaacctgct tccctttgct aaattttgtt attatctttg aaaatagata
     8341 atctgaaagt atacctaaaa atccaataac aaaaattcct accaatacaa catcagttct
     8401 agacatatct tttccatcag aaatcaaata tcctagtcct gaagaagctg caataagctc
     8461 tgctccaatt atagccctaa aactataccc aagccctaaa ctaagtccaa caacaatatc
     8521 cagcatagaa ttagggatta ttattttata aaaaattctc tttttagata aattaaaaga
     8581 tttacctact tctattaatt tattgtcaca attttttata cctttcaatg tatttaaaaa
     8641 tattggaaaa aaggatgcca aaataataat tataatttta gattcttcac ctataccaaa
     8701 ccataaaata agcattggca ccaaagctag tggaggtgta cttcgcataa attcaaatag
     8761 tggtttgaaa tattcataca tttttttatt tactccaaat aaaactccaa gtggtatagc
     8821 catcaatgaa cttattaaaa aacctattaa tatccttctt acactggcat aaacatttaa
     8881 gaaaatagaa ccgtcatata tcatttttat aaaagtatct aagactattt caggaggagg
     8941 cagaatatag ctactccata tacccaaaac acatactatc ttccataaaa ttaaaattat
     9001 taaaaaaata taatatcctt taagcctttt atgaattttc tcaaacatat aaaactcctt
     9061 ttaacatatc tatccctgct acccttttta ttttttaata tcttaaataa taattaagct
     9121 atatcataag atttaatcta tgccaagtct taatccacct gaactcattc tatcagaagg
     9181 tgtagaatct gtttttaagc cagacaatct ttcagatggt tgtataatga ctatttgtcc
     9241 aggttcaaca aattccatat gataagattc tcctgaagtc tgaccaataa aagtcttcca
     9301 tgatagtttt gatactttag gatatggttc tcttccagtc caagctacta atgcatctgg
     9361 gtcaacacaa caaggtcctt caagaattag aggattacca tctgttatta tagcaacatc
     9421 ttgattttga cctgttttat ttactaaatg tgtagtaaaa agaccttttt gagatattac
     9481 ccctgaacca atcaatttta cactgtaatt taattgttca gaaaatgcca ataagttttc
     9541 actctcaaca taaatggaat cacctgggtc aattgatatt acatctacat ggtaagcatt
     9601 ttgagctagg taaatttcac cttcaccttc aaccaccatt attggcattt gttctcctgt
     9661 caatgacctc tgaacatgac ctaataatgc tcttcccaat ccaccgccat tacttggacc
     9721 taacagcaat ttttcaaaat taaaatttcc tttaaaggct accatagcac ctttttttgc
     9781 aaaaaattta ccacttcccc ttgctataca cataagctcg tttgtaacat caaatttaaa
     9841 cataatattc acttatattg cttaatttag caataatccc tcctaatcat atatttatat
     9901 ataattatac agtaaaatta cagcatagtc taacctactt caaatatgaa atttgttatt
     9961 tatacaaaaa ataagaacct gataataaag caatttaact ttttatcagg ctcttatcct
    10021 atttatctct tagcgctatg acaactctta ctacttgagc atccagaaca accacatcca
    10081 caactgctac cattcttttt tgaattttta accatataca ttacagctag tgccattaat
    10141 actactacaa tagctgctat aataaatgta gccatattca tcactcctta tttatatgaa
    10201 ttaatttttc atataactta atttacccat tttttctttt ttcatatttt tatttgaata
    10261 agttaaaact acaaagacta ctgctactgc tataaatata gatattattg ccccagcaat
    10321 acttcctcca gtacctaaaa ctaaacttcc aacttgattt ataagaagag caattatata
    10381 cgctgttaaa gtttggaatc ctaatgtaat ccatgtccat ttccatgaac ccatttctct
    10441 ttttatggct ccaatagctg caaaacaagg tgcacaaagc atattaaatg ccataaatgc
    10501 aaacgcacta gctactgtaa acatgcttgc aactgaagca agaagtgttg ggtcttgctc
    10561 tgttgcatct gatataccaa ataaaactcc aaatgttcca actacatttt ccttagctac
    10621 tagacctgta actgttgcta ctgatgattg ccaatttcca aatccaagag gagcaaatat
    10681 tggtgcaact atatttccta agctagctaa tatactatct ccagcatcta ccatttgtaa
    10741 tgaccaatta aatgattgta agaaccagat tactccacaa gcaacaaata taattgttcc
    10801 tgctttgatt ataaatgctt ttcctctatc ccacatatgt attaaaacac cttttgcact
    10861 tggaatatga tattgaggta attccataac aaatggagat ggttctcctg caaataaact
    10921 agttttcttt aatataattc cacaaatgat tatcattgca atacctaaga aatacattga
    10981 tggagctacc catgaagcac ctccaaataa tgcccctgca aataatgcta ttattggaat
    11041 cttagctcca catggaatga atgtagttaa cataatagtc atttttctat ctctatcatt
    11101 ctctatagta cgagttgaca taactcctgg aactccacaa cctgaactta taagcattgg
    11161 tataaatgat tttcctgaaa gaccaaactt acggaaaatt ctatccatta taaaagctac
    11221 acgtgacatg tacccacaat cttctaatat tgataataat aagaataaaa gcatgatttg
    11281 tggtacaaat cctagtactg ctccaactcc accaattaga ccatcaacta caagtccttg
    11341 taaccactct gctacattta aagaagctag aaaattactt acattgcctt gaataatttc
    11401 tccaaacagt acatcatttg tccaatcagt tgctatagta cccaatgaac ttactgctat
    11461 atagtaaact ccccacatta taagtgcaaa aataggtaat gctagtatac gatttgttac
    11521 aatcttatct atcttatctg atacagtttc cttacctttt cgattcttct ttattatact
    11581 tgaaattatt gaactaataa attcataacg attggctgtt attatacttt cactatcatc
    11641 atccaattca tcttcacaat ttctagttat ttcttcaata ctattcaata ttgttttaga
    11701 aatatcaagt ttttgtataa cattttcatc tctctcaaat agctttatag ctaaccagcg
    11761 tgtttctaca tctatatatg gagtcttttc ttctattatt ttttcaattt tttctattgc
    11821 atccttactt tcatcaacaa agggtaattt gaaatttaat ttattgttac tacttgcaag
    11881 ttcaactgcc ttttcagcag cctccataat tccttgacct ttaactgctg ttacttctac
    11941 cactgggcaa cctataactt cagatagttc tttaatattt atcttatcac cattcttatt
    12001 tacaatatcc atcatattaa gagctataac ggtcggtata cctagctcta aaacttgagt
    12061 tgtaagatat aaatttctct ctatatttga tgcatctaca atatttatta ctgcatccgg
    12121 cttatcatct agcataaaat tacgtgtaac tacttcttct aatgtatatg gagataaaga
    12181 ataaatacct ggtaaatcta ctatttccac atctttattt ccttttaatt ttccaccttt
    12241 tttttcaact gttactcctg gccagttacc aacatattgt gatgagcctg taagcccatt
    12301 gaacattgtt gtcttaccac agttaggatt tcctatgaga cctattttta ttgacatttc
    12361 cattccctcc attattattt aaatacatca ctattcatga tatagaaaat cattctcatt
    12421 atataattac attaactcta ctctaattaa tctttattat tccacaataa ttttttctgc
    12481 atctgactta cgaattgata gttcataatc tctgactgtt acctcaattg ggtcaccaag
    12541 aggagctact tttcttataa atatattaac gcctcttgta atccccatat ccattatacg
    12601 tcttcgtgta gctccttctc cttctaactt tttgactttt acagtctctc cacacttaat
    12661 atccttcagt ctgttcatgt cattacctcc ctatattatt attctacttg ccattttttt
    12721 atctaatgca actctagtat cttttacgtc tattattaag ttaccatcta tcttagaaac
    12781 tattttaaca tttgtaccta ctacaaaacc tatactattt aaaaaagtcc tcgtcttatc
    12841 acttcctgaa attttcttta taactacttc ttcacctgta tttgatagta tcaatggcat
    12901 catataatat ccctcctctt aaactaattt aaatctacaa gcaatcgtta tcttatatat
    12961 aaattacaat accttaaatc ttaatctatt aaaataatat cctatttttt ccttcttttt
    13021 acaattccta attttgattt aagtctatca caatagtata ttttttgcaa gtgattattg
    13081 tattcttttg attttttttc tcatttgatt tattttatta ataaaatcgt aaaaattaat
    13141 acaaaaataa agatgctcta aaatagtata ctcaactaat attaaagcac ctttattata
    13201 tatatcatta cttacacatt gctttattct tttttaaaag caattttttc aaactctttt
    13261 acaggcattg gcttagaaaa caaatatcct tgtaccatgt cacacccaat ttgctttaga
    13321 aattctactt gcgaaatagt ctctacacct tctgatatta ctttcatttt caattccttt
    13381 gccattttaa tgacattaga tataacaatt ttttcattat tactctcatc tttttctgta
    13441 aaaaatgctc tatctagttt taatatgtca acaggcaatt cttttaaaag attaagagag
    13501 gaatatcccg taccaaaatc atccatagag attacaaatc ccttttcttt caaattgttc
    13561 attgtatcaa gtaacccttc tatattatct aatactgctg tttctgttag ctctaattct
    13621 ataagtcttg tcggaatttt gtatttatct acaattaatt taaacttctc tataaaatta
    13681 ctatttacaa aatgcattcg agacaagttt acagatatag gtactacttt ttgtccttca
    13741 tccatccatt ctctaatctt tttacacact tcctcaaata catagaaatc aatatttaca
    13801 ataaaaccat tcctctcaaa tacaggaata aattctattg gtggtattag acctttttgt
    13861 ggattatccc atcgaacaag agcctctgcc cctataattt gataatctga aagactatat
    13921 ttaggttgaa aataaacaat aaattctcca ttattaagag catctaccat tgaattttca
    13981 atttctttct cttttaatat ttttttatgc atttccttat cgtaaaaagc aaatgaattt
    14041 ttatgaccac cttttatagt ttttcttgca gtattagctc tatccataat agtatttatg
    14101 tcattatcac ttttacttat tttatatata ccacaatcta aaatcaattt ataatagttt
    14161 attttaggat tactaagtat ttgaacctta ttgtaaatat tgtttaacct tgttttaata
    14221 tcatcatctg tcttatactt aataagaaga acaaaatggt cagcagaaac tcttgcaaaa
    14281 atttcatctt cctttaattc acttgcaata gtatttgata tatgtatcaa agtatcattt
    14341 cccatatcat atccaaacat atcatttata tatttaaatt tgtcaacatc tatataaaac
    14401 aatgcatatt cttctggatt atttttagca aacagtttat tcgaatttat tttaaattta
    14461 tctatactat ctgctcctgt caatgggtct gtatatgcta tcttctttag ataatcctct
    14521 ttcttctttt tattataaat tatatattta atagcaatta agaataaaat acatacaaaa
    14581 gaaataattt gtattgaata ttctttaaaa atcacaccaa atggtacttt ataaggtttg
    14641 tcaatagtat tagaatatat acaatcactt aattcttctt cagtaatttt gtctattgat
    14701 ttatttaaaa tagatactaa tatagggtca gttttatttg atacccctat acgcatccca
    14761 tagcttgtat ctaaaacaga tataacagat aaattctcac tctttccttc tcttaaaagt
    14821 tcatcaaact gataagaact aagtatcatt aagtttgctt taccttcatt tatagcgttt
    14881 agacaacttt ctatactctt ataagatgtt gtcttagcat tttcaaaact tttttctata
    14941 taagaatcga tagacttata actactcgtt aaagcaatat ttaaatcatt attgagattg
    15001 gtatccagtt ttcctaccat aatcattgga atatttatgt atggatttgt caatttcata
    15061 ttaaatcgtt ttgccttatc attttcattg attgagccac atagcatatt tgccttacca
    15121 ctttttatgt aatcaagact ctcattataa ttttttgttt taatatattc aaattttata
    15181 ccacattttt ttgatataat tgacattaaa ttggaactta tacctttaaa cgaattgctt
    15241 tccttatcat aatactctac aggagaccac tctgaatcat ataccatagt aagttttggg
    15301 tttgctttaa taaaattcat ttcttgccga gtaaatgcta tggaattatt gacctctctt
    15361 ttgaaatatt ttttatataa ttccaactca taatacatat catttatttt taattctttt
    15421 aaagcataat ctaattcttt taccaaatta ggtttatatt ttgcagtagc aaaataaaaa
    15481 ggctctactg aaaatttgct aactattttc attcctttag catttataat acttccacag
    15541 acaaatgcat ctgccttttt ttcattgaca gactcaatta attcatcaat agaattacag
    15601 tagatatatt caactgaaaa attattttct tctctatact tctcaaatgc aatattatga
    15661 aagtttcctc taagtacagc tactctcatt cccttaaagg aacttatatc ttcataaaac
    15721 atattattgt tactatcttt tgtatatagt acactatatt catatcctga atttagttta
    15781 ggaaaattaa atagtttatt tctttcatca ttcttctgta aaggtccaag taagtctatt
    15841 tcaccttttt ctagtctgtc taaacattct tcccaagacc cttttacaaa ttcatattcc
    15901 catcttgtat attttgagat ttctcttaga taatcataac catatcctgt ataagaatgc
    15961 tcttttgatg aggatattat tccgtagtca tcacaatatc caactcttat tttttttgaa
    16021 ttttcagact catcagcaaa gcatagtata ttgttaaaac atgatataat aagtaaaaat
    16081 atcaaagaaa gtatcaagaa gtgcttttta aatgctttca tatttaaaaa cctccaattt
    16141 gccaacttac tttaacttat ttggttttct agttgtaact acttttattg taatggtaaa
    16201 tatatcaaat tgcaatattc tcatataata ttcttattca actataatga atttattatt
    16261 atctatttaa atacactatc taatattagt ttcttataag tcataaaagc acaactaaca
    16321 ctataattct agtgattaat tttatttcaa aaaatataat aacactacta atattttaaa
    16381 tatcaatagt gtcataaaaa cttttcagat taattaaatc tttctatata ttttataata
    16441 atctaaatca tgctaaatat ttagacagaa aacttttttc tttaatagta aatacttttg
    16501 tttgaatatc agaataatta tttgaatatc tatctataaa accatgattt gcatctaaaa
    16561 tctcaatttg gatattttgt ttcctagaaa gttggtaaga aatagaatca acatcaaatg
    16621 aatcgtgctt tgcaaatact aataaggtag gacattttgg aattacatcc atgtaatctc
    16681 gaatccgaga gccataacaa caaattatgc catcacaaaa agaatcttca ctgcatctcc
    16741 atgcaatagt tgctcccaca ctatacccag caacaaatac atatttatac tctgatttta
    16801 aatcatttat aagcttttca acttttttat aaatatcaaa accaacatta tttataaaaa
    16861 aatcatatgc ctcttggact tttgaatatg gaaaaactct tttttctccc agaagttcag
    16921 gacaaaatac atcatatcca tatttataat acttttgaca aacatcttct ataaagctat
    16981 taatcccata gatttcatgt aaaacaacaa tagctacata acttttatgt atatacttta
    17041 tcagattatc caccaccttt acaaaacagc aaatttttta tacttagttt aatatattct
    17101 tctttacatg tcaatttact tttctaaaat caaatttatt tttggattaa tcatttattt
    17161 ttaaaagttg tgcattatta ctattaaatt attctctatt attaaaaata taatcgttag
    17221 aaataaaaaa taaagtacaa ataattaaaa aatatctcac tcataacttt aaaaattgta
    17281 agtgagatac tcctaaaatc tactttatat taaatttatt ttccaaaata tctatttaat
    17341 aatcctaaga atgctttacc atgtctagct tcatctttac acatttcatg tactgtatca
    17401 tgtatagcat ctaatcctaa ttcttttgct ttcttagcta attttaattt tccatcagtt
    17461 gcaccatact cagcatcaac tctaactctt aagttttctt ttgtatctgc aactacaact
    17521 tctccaagaa gttctgcaaa tttagcagca tgttcagctt cttcaagagc tattctctta
    17581 taagcttctc ctacttctgg ataaccttct ctatcagctt gtctactcat tgctaaatac
    17641 attcctactt ctgtacactc accaacaaag ttagctctta atccttcgat tatttcttca
    17701 tctacacctt gagctactcc tattctgtgc tcatcagccc aatttttttc gcctttcatt
    17761 tcttcaaatt tatcagctcc aactttacat actggacatt gtgctggtgc agcatctcct
    17821 tcatgtatat atccacatac tgtacaaaca aatttcttca taattacttt cctcctaaat
    17881 tttatatatc aaattaaatt ttttatttat taagttagtc tatatatacc cgcaccatat
    17941 acctttaaac aattttttta aaagtttttt ctaaatactt attttccctg tgtcaataat
    18001 atgtttctat aataatgtcc ctttaatttt atcaattctt tatgatttcc tgattccaca
    18061 attctaccat tttctaaaac tattatatta tcacaatttg atatggtact taatctatga
    18121 gctataatta tacttgtctt tccataagtt aaattattta ttgcttcttg aattttagct
    18181 tctgttgcta tatctatgtt acttgtagcc tcatccaaaa taagtattgg agcatttttt
    18241 aatactgctc tagcaatact tattaattgt ttttgacctt cacttaaatc ttcaccccta
    18301 tccgataata cagtactata tccttcacgc attttaacta taaatttatg tgcatttgct
    18361 attttactag catatataac ttcttcatca gtagcctcca gatttccata ccttatattt
    18421 tccataactg tatcattgaa tatataacct tcttgtggaa ctactccaaa acaagttctc
    18481 aaatagtttc tgttaataga gtatatatcc ttaccatcta aaaatatact tccttcatct
    18541 atatgataaa aatttgtaat tagatttata atagttgttt ttccacttcc cgtctctcct
    18601 atgatggcat ttgatgtgcc agatttgatt tttaggttta tattatctaa aattttcttt
    18661 tttgaatcat aagaaaaact tacatcttta agctcaattt ctccctttac aaaatgagag
    18721 tttaaattac catctttatt atcgttaatc tcacttttaa acatgttatg cacttcttgc
    18781 tcttcttgtt catctataat ttcaaaaact ctttcacatc cagctatggc tgaaagtaat
    18841 gtattaaata gatttgctaa ttcatttaaa ggtcttgtga attgtcttac ataacttaaa
    18901 aaactagcta taacccctat ggttataata tctttagatg caagaatgcc tcctataata
    18961 catatagttg caaatcctat attactaatc acattcataa taggcattaa aagagaagtg
    19021 taaatttgcg atttaaggga aatatttaga agtctatcat tgacttcttt aaaatcattt
    19081 acagattttc tttcataatt aaaagatttt actacattta tgtttgatat catttcttca
    19141 atatgtgcat ttagttttcc caactcaact tgttgttgct taaaaaaaac tctagttctc
    19201 tttgcaataa aattactcac aaacattact atcggtatta atattacact gcaaaaggtt
    19261 aaaattgggc ttaatacaaa catcataata aaagtcatca atatgtttaa gattcctgta
    19321 attaactgta ctaatgaatt tgatattcct gtactgatat tatcgacatc atttgtcact
    19381 ctactcataa tatctccagt agaactttta tcaaaaaagg ttattggtag atttttaaat
    19441 tttaaaaata aattacttct catttctctg actatacttt gagataatct agctgtacat
    19501 attcccttag acagtttaac tgaaaactca attatataaa atgaaagtaa aataattatt
    19561 ccttttaaga aaatggattt tgaataagta tcgatatcta ttatgtcaac tacctttcca
    19621 atagtatatg gtattacagt tgatataatt gaatcaatta ttactagcaa aaaaataaat
    19681 ctagtaatct tcttatcttt tttaaagtac ataaaaattc ttttaaacgt ttttttaaaa
    19741 tctttaggct tttctttttt ctttaatcta ctgaccttct gatttccagt acttaaattc
    19801 aatatacttc ctccttaatt tacatcttca cttactaaat tttgcaacgc aaaaattttt
    19861 ttataaattg gagaactaac cagtaaatct tcatgtgtag caaatccaac cacctcaccc
    19921 tcatccaaga ctaaaatctt atcacagtca attatagaac taatcttttg tgaaatagtt
    19981 attacagtac atttcttact ttccttttct cttaaattac ttatatactc ttttatattc
    20041 tttcttataa ttgtctctgt attaatatcc attgcactaa aacaatcatc aagaattaat
    20101 atttgtggtt ttttggctat agctctagct atagtaattc tttgtctctg tcctcctgat
    20161 aaatttttac ccctttggaa taaaacttca tcataagtat tttcgagttt tgttataaat
    20221 tgatttgcat ttgctatttc acatgatttt acaacatcct ctttgcatat atctctattt
    20281 cccataacta cattctccaa tatacttttt ccaaacacac tactattttg aaatactaca
    20341 cctattcttg cccttaaact ttcttcagaa atactgtata tactacgtcc tccaatctta
    20401 atatcacctt tatcaattat atataatttt tgaattaaat ttactaaaga agtctttcct
    20461 gaaccagttt gaccaatcac accaatattt tgaccttctt ctattttaaa ggatacgttt
    20521 tttaatattt tttcatctgt atttttgtta tacgaaaaat ctacattttc aaaaattata
    20581 tcacagttta caaactttaa atctttttct ccaacatcta aactttcttc tctctcaatt
    20641 acttcttcat tctcatcaac caaaacctca cttattctct cataagatgc ttttgcccta
    20701 acaaaaacat taaaaacatg tgaaatcatt ataagagatg ttaatattct agtcatatag
    20761 tttacataag caactataat cccaatttta atttctcctg aataaattaa atgccttcca
    20821 atcagtaata ttattattat ggaaacatta atgattattg taattgtcgg tctaaaaaat
    20881 gacatcatag ttgtagcttt tctactattt ttaaaaagtt catcatttaa ctcttcaaag
    20941 ctttggttct cataatcgta tctacaaaat agtttaacta cttttattcc acttaaaaac
    21001 tgtcttaatt ttgaatttac tttatctgta ctttcttgta catttttaaa taatctatac
    21061 cctatcttca tattaagcaa tattataata aatataatta aaactgcaat tagaataatt
    21121 attgacatct ttaaatttaa ttttatagct ataattaaac ttcctataca cattattggt
    21181 gactttataa aaactctcat cattccatta acgaattgtt gcatttgatt gatatcatta
    21241 gtaattcttg ttattaatga agctctacca aatttatcta tttgttttaa tgagtatgta
    21301 tttatctttt caaatacatc ctgtcttaaa tcataagaaa aatgctgaga aactcttgcc
    21361 gagattacac ttcttattat tgcaaatatt gcacctaaaa aagttatacc tatcattata
    21421 gctcctgttg atagtatgta gtctaagttc ttatttgaaa cccctatatc tattattttt
    21481 gccattatag ttggttgagc taaatcacaa aaagcttcca atgttaaaaa aaatactgct
    21541 gttagaaata atactatata tttttttatg tattttttaa aatacctcat tcaatcatcc
    21601 cttcatagaa ttttctcatt accaaaagta tatcataatg gctaatttaa ttgattatat
    21661 caattataaa tatttgattt attattaatt tttatacc
//
LOCUS       DAEPKC010000067        21611 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.067, whole genome shotgun sequence.
ACCESSION   DAEPKC010000067 DAEPKC010000000
VERSION     DAEPKC010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21611)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21611)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21611
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.067"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..282
                     /locus_tag="KR294_002526"
     CDS             <1..282
                     /locus_tag="KR294_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HBH0240596.1"
                     /translation="LKTTSITLIIMPLLLTVPILLNFEKSFIIFHKLLFRNDYWIFNP
                     DLDPVINILPEEFFFHSGMMILILILLVSIVLFVMYKLCKSLSIKIFQC"
     gene            complement(424..684)
                     /locus_tag="KR294_002527"
     CDS             complement(424..684)
                     /locus_tag="KR294_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich small domain-containing protein"
                     /protein_id="HBH0240597.1"
                     /translation="MGENYKFFNHKDCEFFPCHKTNKPEEFNCLFCYCPLYALGENCG
                     GNFKYTDKGIKDCSSCILPHKKDNYNYIMSKFQDLVKITSKK"
     gene            901..2184
                     /gene="hflX"
                     /locus_tag="KR294_002528"
     CDS             901..2184
                     /gene="hflX"
                     /locus_tag="KR294_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HBH0240598.1"
                     /translation="MKEIQEKALLVGLNLTTIVKKNDDIDTNESMEELKELTKAAGAE
                     VVGSLIQNKHSVDAAYYIGKGKVEEIRAYSDSLDATLVIFNDELSGAQIRNIENVVGR
                     KVIDRTTLILDIFAQRALSKEGKLQVELAQLKYRLPRLYGMGGEMSRTGAGIGTRGPG
                     EQKLEIDKRHILNKAADIRRELKEVKKNRETQRVKRLKSNIPIVALVGYTNAGKSTLL
                     NELIKTHKDYEQEKEVFVKDMLFATLDVTLRKALLPNKKEFLVVDTVGFVSKLPHDLV
                     EAFKATLEEVQYADLILHVIDATNTSYELQKSTTEGVLKELGVNDKKHILVYNKVDKL
                     ELDIYPKSQEDIVYISAKQGINMDKLLNMIEIALMENTYSVSLMLPYERGDIFSRIKD
                     KYNVENFEYGESGITLDVDLDEEDFNIYREYILEK"
     gene            2192..2869
                     /locus_tag="KR294_002529"
     CDS             2192..2869
                     /locus_tag="KR294_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HEAT repeat domain-containing protein"
                     /protein_id="HBH0240599.1"
                     /translation="MDINWENIDNLEDYFITYLLYKESKTVSQISKIRNISSTEASEQ
                     LIQAKLKIKEMQKDDFEASKDILDKFLELDKIKRLDFMDSLDDEKMVYFKRKVFKRIL
                     VEKNAEDLIVLIWATGELKDDRFLKLLHQLTNHRHSDIRRITYSAIRKIESPSSREVL
                     QKGLYDKNAQTRQYCAKALSKLGDENSLKILQQLKDKNKNFEKEYVLRAYDKAIKSLE
                     NAKNLKK"
     gene            2955..3398
                     /locus_tag="KR294_002530"
     CDS             2955..3398
                     /locus_tag="KR294_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBH0240600.1"
                     /translation="MIVRRCAGGVVFYANKVLIVKNDRGEWTLPKGKILGGGLPYESA
                     VQRVKVETGIDAKMIDVAGDTMYEFFSRSRQQEVCNAIMWYVMEACNTDCVLAPEFQE
                     GGFYKVKDALEMLSHHKEQALVEVSYKKFKELKKLVSEGDDVPAN"
     gene            3703..4347
                     /locus_tag="KR294_002531"
     CDS             3703..4347
                     /locus_tag="KR294_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HBH0240601.1"
                     /translation="MSNYRTLHEFGMDEITIEKSVFIGYAKPIKSEEEALEFINEIKK
                     KHKDATHNVWAYTVGKNMNIQRYSDDGEPQGTAGIPTLEVIKKEDLRDVAVVVTRYFG
                     GTKLGAGGLVRAYTKGAKLGLEAGKIIYKVMYQEVKVKIDYTQLGKVQNELMNLGYFI
                     KDTVYEDNVEIVVYSRLEDVEKLSEKMIDITSGTGKIVLGEEFYLSEQNGEILI"
     gene            complement(4433..4810)
                     /locus_tag="KR294_002532"
     CDS             complement(4433..4810)
                     /locus_tag="KR294_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HBH0240602.1"
                     /translation="MLFALIGFFAGIIGGMGMGGGTILIPALVLLAGIDTKIAQSVNL
                     LSSIPMTLIALAIHIKNKNVIFKLVIPIAVFGVLGAVFGSLLANYLSSDILKKIFGIF
                     LLLVGLFEVKKGFCAKSDKKPLN"
     gene            complement(4810..5196)
                     /locus_tag="KR294_002533"
     CDS             complement(4810..5196)
                     /locus_tag="KR294_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HBH0240603.1"
                     /translation="MKKTDDLKKKYFDFNLKNTIIGVFTGFINGVFGSGGGTLLVPIL
                     NDIVKVEEHKSHATALSIIIFLTTASSVLYVSKGTYDVNLTIKVAVGSILGGIIGAKL
                     LNKVTGKFLRISFGIIMIIAALRMVF"
     gene            5375..6130
                     /gene="nadE"
                     /locus_tag="KR294_002534"
     CDS             5375..6130
                     /gene="nadE"
                     /locus_tag="KR294_002534"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+) synthase"
                     /protein_id="HBH0240604.1"
                     /translation="MSNIKIQIDKTVEWLINKVNEANAKGLIVGVSGGIDSAVVANLI
                     KKAFPENSMGVIMSIKSNPQDREDALKVIEGCDIEYLDLDLIEPQSAILDMVVGNLKD
                     KHLYREEYLKMTDANLRARVRMSTIYTIANNLGYLVVGTDNAAEIHTGYFTKFGDGGV
                     DILPIANLTKGEVYEWAKELGVHEDLINKAPSAGLWEGQTDEDEMGTTYNMIDAVLEG
                     RLDEVPKRDQEIIERLHRLSEHKRKTPAQPPKF"
     gene            6213..6932
                     /locus_tag="KR294_002535"
     CDS             6213..6932
                     /locus_tag="KR294_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBH0240605.1"
                     /translation="MGRIGNIINRKGKQDAQRAKIFTKHARAIAVAAKEGGADPEYNA
                     ALKTAIEKAKADNMPNDNIDRAIAKGAGAGAGEDYETIVYEGYGPGGVAVIVETLTDN
                     KNRTAGNVRYYFDKNGGNLGTSGCVSFMFDKKGQILVGLGDGVSEEELMDVALEAGAE
                     DFITEEDGYEIITTPEDFSSVRDELKAKGYEFISADVKMIPQTTTVLTEESHLKMMNK
                     LVDMLEEDDDVQDIYHNWEVE"
     gene            complement(7099..8103)
                     /locus_tag="KR294_002536"
     CDS             complement(7099..8103)
                     /locus_tag="KR294_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HBH0240606.1"
                     /translation="MATIKDIAKDCGLSSATVSYVLSGKGNERRIPLHTQELILNSAD
                     KLGYKRSTPIKHNNIKIAFYWQDEGFELASTNILQAINHIISLEHLNINIIIRPYKVG
                     HLCDDEYFFANNYYDGIVLTGINADDIEYLVKNKPKIPVVVVNREIPGFSSVSIDNEE
                     TGRIAALHAIQNGKNDIAVVFNPTSFTCMTLRGKSFLKTCKEHGIHLSDSIYYCSNKI
                     DSGYDIAQKMLAKNSLKKVIFCNHDVVALGMMNAFHESGIVIGEDIQIFAASNGPSRL
                     MARSIPPLTVIDLKMEETAERSLRMIIDTVTGRINGIQQQVIYPSIIYRQSSPAQNLL
                     "
     gene            8369..9265
                     /locus_tag="KR294_002537"
     CDS             8369..9265
                     /locus_tag="KR294_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA lyase"
                     /protein_id="HBH0240607.1"
                     /translation="MSKVNIFEVGPRDGFQNLKEFLETDKKLKIIDGLIASGIKQLEI
                     SSFVSPKAIPQMKDAKEVATYCVEKYPDVKLYALVPNLYGAKVAWECGIRDISYVISL
                     SETHNKKNINRTHEESIDELKKIMNTYPDMNICIGMATVFGCPFEGLPKIEDAIRFAK
                     RLWENGIREMNLADTIGIADPKQVRETISALVEALPECRWQVHIHDTRNMGMVNTLVA
                     IESGITTVQSTLGGLGGCPFAPGASGNTATEDLVYMLERMGYDTGVDFVKLLELSKYQ
                     KSFVNGVYSGHHVNIKSDSCNC"
     gene            9403..10665
                     /locus_tag="KR294_002538"
     CDS             9403..10665
                     /locus_tag="KR294_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240608.1"
                     /translation="MDIIALLLFLGVIIIAFVRKNNAGILALAIGVIAVRIFGMDDKE
                     LYGAISNSMFTTLVGITLLFAIVNSTGALKLVAEKIVAASGKRVWLIPIAVFIAGFVV
                     AGVGPGAIPALAIIPAMAVPVAITVGYNPVMLALIGECGLMAGRMTPITPEGQIITTV
                     AEGVGIENVMPTILACQTLSTIVFSIVLFIIFKGYKLKKPINVIDSKQIEKFNIKQII
                     SLISIVVMIAFIIIFDMNVGLAAFAVSAVLIFFNIADEGECIKSIPWSTIVMVLGVGA
                     MMTIVDAAGGIDLMSNALSSLMNSKTATPIMSISAGLMSMVSSALAVVYPTMMPMCVD
                     IAKAVGGVDPLALIAAVGVGGSLAGVSPLSTGGALILAAMGSSKKDFNKEEQNKVFVQ
                     LFIMSAVGLLVIAVVSILSFNAITHLMN"
     gene            10741..11934
                     /locus_tag="KR294_002539"
     CDS             10741..11934
                     /locus_tag="KR294_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase"
                     /protein_id="HBH0240609.1"
                     /translation="MKKGALSNIKVLDLTRVLAGPYCTMMLADFGADVIKIEMPRKGD
                     DTRGFGPFVNGESLYYANINRNKKGITLNLKSEEGKNIFLEMVKHADVVVENYRPGVM
                     EKLGLGYDELAKVNNQIIYGAVSGFGCYGPYSERPGYDIIAQAMGGLMSITGQEGGEP
                     TRVGNAMGDVLGGMNLTIGILTALNARKIIGKGQRVDVSLVDSVVSSLETGIQRYFDS
                     GQPELMGNRYASAYPYDSFKASDGSFVIGCGNDKLFEKLCKKVLFREDLLIDERFKTN
                     LNRCEHYKALKPEIEKWSIKHTIKEAVDLISEAGVPAAPIYNLDCVTTDEHIAKAREM
                     IVDISHPIIGNMKVNGNPVKLMTTKAKIDMPAPSLGESNEEIYNGWLGFDSDKIKDLK
                     ENGVI"
     gene            12563..13357
                     /locus_tag="KR294_002540"
     CDS             12563..13357
                     /locus_tag="KR294_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="HBH0240610.1"
                     /translation="MESVMENLNNLKVEVKDKVCVITINRPKALNALNSDTLRELSQV
                     IDVVSENEAILGVIITGEGKVFVAGADIRQMQNYKSEEGRKYAGYAQGVFDKIEALEK
                     TVIAAVNGYALGGGCELAMSCDIRIASEKAIFGQPEVNLGVIPCFGGTQRLSRLVGTG
                     IAKELIFTGRQVNAEEAKSIGLINKVVPSDLLLEESMKMMNQIVEKAPIAIRYAKVVI
                     NKGIDMDLKNALELEKDIAGLTFATRDKQEGMNAFIEKRKPVFENK"
     gene            13452..14792
                     /locus_tag="KR294_002541"
     CDS             13452..14792
                     /locus_tag="KR294_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HBH0240611.1"
                     /translation="MNTGVIISLVGIIIALSLLVVMVMKGINIFIIAIVCSSLVAITG
                     SLNVYDALKVDYMTGFVGFLQANFFIFLTGTLMGKIMEITGGAKSIAKMIVRWIGKDK
                     ALLSIPIACGILAYGGVSVFVVSFAVFPIALEIFKEADLPRRFIPAALTFGCSTFAMV
                     APGAPQIQNIVPASTLGTDIMAGAVNGFISCAVMFIVGSTILYKMVSKEKANGGHFIA
                     HESDIFDEAEATNSKRENGPNGVIALIPLIVSILIINVKVNGKAIVPIEVGVFIGALL
                     VYLLLNKYQDNTKIVGHVGDACKTTVVAICNTCAVVAFGSVVKSAVGFDFIVNAMTNI
                     PGPPIAGAAVGTTVIAGICGSASGGLGIAAPLLGPVFLAKGVSAAALTRTMAISSAAL
                     DSLPHNGYIVTVTNGLCKETHKDAYMPIFWVTVLTPFIGTIVAVLLFTMFPGLP"
     gene            14929..16161
                     /locus_tag="KR294_002542"
     CDS             14929..16161
                     /locus_tag="KR294_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase"
                     /protein_id="HBH0240612.1"
                     /translation="MLNKPLEGVKVIDLTYFVAGPGTSKILADWGADVIKVEPSFGDP
                     GRKTGATMTMPIDDYNNPFYSTYNSNKRGLSINLKSETGIEIMDKLLSEANVFVSSYR
                     TGALKRLGLDYESLSKKHPHLIWGQINGFGDFGPAKDNAGFDTVAFWARSGAMLDIAE
                     KDTSPINPPIAFGDATTSCSLSGGICAALYQQAKTGKGQKVMASLFGQAIWNASSLLA
                     STQFSDEYPKTRKNAISPVINSYRCKDGKWIFLSILEHERYFEALCRLFGREDLIKEE
                     KFASSVESKKNATELINILDGEFAKFTQNEMVEKLTAADIAHEKIQHVNDVVTDEQAI
                     ANNYIYEHTSKDGNKTMLASTPVKFGNIEVNMTCDAPLIGEHSDEILRELGYSDSDIE
                     ALIESGIVTMNKEACEIC"
     gene            16201..17343
                     /locus_tag="KR294_002543"
     CDS             16201..17343
                     /locus_tag="KR294_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="HBH0240613.1"
                     /translation="MDFRLTEAQLMLQRVAKEFAENEIAPIAAETDKTGIFPRELFSK
                     MAKIGFNGIGTPVEYSGSGGADIEKVIVVTEIAKKCAASAAILSIHTIYAQAILKFGT
                     EEQKKKYLPMMAEGGCVGAFALTEPNAGSDAARAATTAIIDEETDEYVLNGTKCFISG
                     GGQAESLIIFALTDPSKGIKGMSAIIVDKGTPGFSIGKIEEKMGIHGSETAELIFDNC
                     RVPKSNLLGKEGKGFNIAMTCLDGARIGVGAQAVGIAEGALEESIKYSKERVQFGKPI
                     SALQGIQWYIADMATMVESAKLLVYYAADLKARGEKHTKEAAMAKYNASRTAREVTNL
                     ALQIHGGYGYMKDYPLERMYRDAKITEIYEGTSEIHKVVISRAVLG"
     gene            17354..18148
                     /locus_tag="KR294_002544"
     CDS             17354..18148
                     /locus_tag="KR294_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HBH0240614.1"
                     /translation="MNIVVCLKQVPDTNEVKINKETGTLIRDGVPSIINPDDRNALEE
                     ALKMKDELGAVIKVISMGPPQAKSALKEALAMGADEAYLISDRAFGGSDTWATSTIIA
                     AAIEKVGKYDVIFCGRQAIDGDTAQVGPEVAEFLGIPQVTYAKEVKVQDDKLLVTRYT
                     ETGDYLIEAKMPVLLTAIKELNNPRYPSVKGILEAYNNGDAKITVLTLADLDVDTTQI
                     GLKGSPTNVYKSFVPVKDKHNEIIEGINKKEKAEKLIEILFDLKLV"
     gene            18159..19181
                     /locus_tag="KR294_002545"
     CDS             18159..19181
                     /locus_tag="KR294_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HBH0240615.1"
                     /translation="MMRAKVNQGINLNDYNGVWVIGEQREGKINPVTIELIGEGRKLA
                     DQLGKELAVVIAGYEVEKEVKELLHYSVDKVYYINDPLLKDFTTDGYAISIANLIERK
                     KPEVVLVGATSIGRDIAPRIAGKVGTGLTADCTKLEIDSTDNKLLQTRPAFGGNLMAT
                     IVCPKNRPQMSTVRPGVMAKAVRNESETGILEVVTPELTEKMIRTRLVEILPQEKKSV
                     NLTDARIIVSGGRGLKRAEGFELIKELADKLGAEIGASRAAVDSGWIEHSHQVGQTGT
                     TVRPELYIACGISGAIQHLAGMSDSKYIVAINKDAKAPIFSICDYGIVGDLYEIIPEM
                     IESLNR"
     gene            19280..20656
                     /locus_tag="KR294_002546"
     CDS             19280..20656
                     /locus_tag="KR294_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent Fis family transcriptional
                     regulator"
                     /protein_id="HBH0240616.1"
                     /translation="MKEQWYKDIFARVLSMTDDGFIVVNRSGVIIDINDKYCDFLGKE
                     RKDIIGQNIQSIIPNTKMLDVMKNKYCEEGAIHHYSGGNTKEKSVIVSRSYVENDNGE
                     VVAGVAQVKFRLQSFDVAKKLMSEYMELQYYKEQFKDNCGFDKLIGENRDFIELKKTG
                     VKASKTNFPVLLTGETGTGKEVFARAIHNNSSRSDKPMVSINCAAIPEELLESELFGY
                     DEGAFTGAKKGGKKGKFLVANNGTIFLDEIGDMPLTMQAKLLRVLQESEIEPVGGLKT
                     IKIDVRVISATRKNLSKMVEEGLFREDLYYRLNVINIHMMELKDRQDDILLLANYILN
                     KLNVEYKELKVLSDKVKNCFINYTWPGNIRELQNVIKSAYAVSDDMVIMMCDLPSKMD
                     NISRVAQCNVDSNCSIHEMVENYEKSLIIDVLRKYNWKCSKAAEVMGIHKSLLYKKIK
                     KYEIELNN"
     gene            complement(20988..21332)
                     /locus_tag="KR294_002547"
     CDS             complement(20988..21332)
                     /locus_tag="KR294_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240617.1"
                     /translation="MDQIKRLHELQQKSYLTKEEFEELKNNTYIERFELRDECDNSYI
                     YTFYTNDKCNDIKFIKSQFIVTLIKIGFLCECGGVFRQKKIVDEYDYGYNAIYKCDSC
                     GKELDKEVENYD"
BASE COUNT         8120 a         2545 c         4130 g         6816 t
ORIGIN      
        1 ttaaaaacta catcaataac acttataatt atgccattat tattaacagt tccaatttta
       61 ttaaattttg aaaagtcatt tattattttt cataaattat tatttagaaa tgattattgg
      121 atatttaatc ccgatttaga cccagttata aatatattgc cagaggaatt tttttttcac
      181 tctggaatga tgattttaat attaattttg ttagtaagta tagtactgtt tgtaatgtat
      241 aaattatgta aatctttatc aataaaaata tttcaatgtt aaatagaggg atatttttat
      301 ttccaaaata agataataaa aaaggattag attaaaagtt atacaataaa aatagctgtg
      361 caataatatt tagactatga aagtagttaa aaaatattta tgcacagcta tttataatag
      421 aatttacttt ttactagtga ttttaactaa atcttgaaat ttactcataa tgtaattgta
      481 attatctttt ttatgaggta atatacaact actgcaatct ttgatacctt tatctgtata
      541 cttaaagttt ccaccacagt tttctcctaa agcatacaaa ggacaatagc aaaatagaca
      601 gttaaactct tctggtttat tagttttatg acaagggaaa aattcgcaat ctttgtgatt
      661 aaaaaactta taattttcgc ccatattttc ctcctaatta aataaaattt aaatttttta
      721 tactatataa gattttggtg ataatataat tatactaaat aattttatga atagtcgata
      781 atatagtatt attaatcata gtattaatgg tataattagt caacagaaaa ataatgtaaa
      841 aataatgtaa gtgtattttg taattagaat atgttttata acaaaaaatg aggtgattaa
      901 gtgaaagaaa ttcaagaaaa agcacttctt gtaggtctga atttgactac aatagtgaaa
      961 aaaaatgatg atatagacac taatgaatct atggaagaat taaaagaact aacaaaagct
     1021 gctggggcag aagttgtagg tagcttaatt caaaataaac actctgtaga tgcagcttat
     1081 tatataggaa aaggtaaagt agaagaaata agagcctata gtgactcttt agatgctact
     1141 ttagtaattt ttaatgatga attatctggt gctcaaatca gaaatataga gaatgttgtt
     1201 ggaagaaaag taatagatag aactacttta attttagata tatttgctca aagggcactt
     1261 agcaaagaag gtaaattaca agttgaatta gcacaattaa agtatagatt gccacgactt
     1321 tatggaatgg gtggtgagat gagtagaaca ggtgcaggga ttggtactag aggtcctgga
     1381 gaacaaaaac tagaaataga taagagacat atacttaata aagcagcaga tataagacgt
     1441 gaacttaaag aagtaaaaaa gaatagagag acacagagag ttaagcgttt aaagtcaaat
     1501 ataccgattg tagcacttgt tgggtataca aatgcaggaa aatctaccct gttgaacgaa
     1561 ttaataaaga cacacaagga ttatgaacaa gaaaaagaag tttttgtaaa agatatgctt
     1621 tttgcaactt tagatgtaac cttgagaaag gctcttttgc cgaataaaaa agaattttta
     1681 gtagtagata ctgttggatt tgtaagtaaa cttccccatg atttagtaga agcgtttaag
     1741 gcaacattgg aagaagtaca gtatgcagat ttaatcttac atgtaattga tgcaacaaat
     1801 actagttatg aattgcaaaa aagtacgact gaaggtgtat taaaagaact tggtgtaaat
     1861 gataaaaaac atatacttgt atataataaa gtggacaagc tagaattgga tatatatcct
     1921 aaaagtcaag aagatattgt gtatatttct gcaaaacaag gcataaatat ggataagtta
     1981 ttaaatatga tagaaattgc tttaatggaa aatacttatt cagtaagttt gatgttacct
     2041 tatgagagag gtgatatatt tagtagaata aaagataaat ataatgtgga gaattttgag
     2101 tatggggaaa gtggtataac gctagatgta gatttagatg aagaagattt taatatctat
     2161 agagagtaca tactagaaaa ataggttgaa tatggatata aactgggaaa atatagataa
     2221 tcttgaagat tattttataa cctatcttct ttataaagaa tctaaaacag tatctcaaat
     2281 tagtaaaatt agaaatattt caagtactga agcaagtgag caacttatac aagcaaagtt
     2341 aaaaataaag gaaatgcaaa aagatgattt tgaggcatct aaggatattt tggataaatt
     2401 tctagaacta gataaaatta agagacttga ttttatggat agcttagatg acgaaaaaat
     2461 ggtatacttt aagagaaagg ttttcaaaag aatccttgta gaaaaaaatg ctgaagattt
     2521 aattgtttta atttgggcga caggtgagct aaaagatgat aggtttttga aattgcttca
     2581 tcagctcaca aaccacagac actcagatat tagaagaata acttattcag caatcagaaa
     2641 gattgaatca ccaagtagta gagaagtact gcaaaaaggt ctctacgaca aaaatgcaca
     2701 gactaggcag tactgtgcaa aagctctttc aaaattggga gatgaaaaca gtttaaagat
     2761 tttacagcag ttgaaagaca agaataagaa ttttgaaaaa gaatatgtgc ttagagctta
     2821 tgacaaagcc attaagtcat tggaaaatgc aaaaaatttg aaaaagtaat tttttattaa
     2881 agcaatttgt ttacttaatg atgtatttct aaagtttaac aaggtaataa ataaattaat
     2941 gggaggggtt tcaaatgata gtaagacgtt gtgcaggtgg agtagtgttt tatgctaata
     3001 aagtacttat tgtaaaaaat gataggggtg aatggacact tccaaaagga aagatactag
     3061 gagggggact tccatatgag agtgctgttc aaagagttaa agtagaaact ggcatagatg
     3121 ctaaaatgat agatgtggct ggcgatacta tgtatgaatt tttctcaaga agtagacaac
     3181 aagaagtttg taatgcaata atgtggtatg ttatggaagc ttgtaacact gattgtgtac
     3241 ttgctcctga atttcaagaa ggtggatttt ataaagtaaa ggatgcttta gaaatgttat
     3301 cacatcataa agagcaagct ttagtagaag tatcttataa aaagtttaag gaattaaaga
     3361 aattagtttc agagggcgat gatgttccag caaattaatt gtgaatttag aggattctga
     3421 ggaagggata gccccttcct tttttaattg aagcagtttt aagcgtaaat tatatagtct
     3481 ctttaaacta tgatttatca atttagagat ttagtagttt atatttaaaa tcagtaagat
     3541 atatttaaaa taaaaattaa aaagtataca attttattat ataattgtct tatgatgttg
     3601 attaaagaat tattaaaagt ccatttattt ttaaatagaa taattttata aatatatatt
     3661 tgatgtgtat attagaaaat gattaaaata ggaggaaata caatgagcaa ttacaggaca
     3721 ttacatgaat ttggaatgga tgaaataacg attgaaaagt ctgtttttat tggatatgct
     3781 aagcctataa agagtgaaga agaagcatta gagtttataa atgaaataaa gaaaaagcat
     3841 aaagatgcaa ctcacaatgt gtgggcttat actgtaggta aaaatatgaa tatacaaaga
     3901 tatagtgatg atggagaacc acaaggaaca gctgggatac ctacattaga ggttataaaa
     3961 aaagaagatt tgagagatgt agcggttgtt gttactaggt attttggagg aacaaaatta
     4021 ggtgcaggtg gtctagttag agcttataca aaaggtgcta aactgggact tgaagcaggt
     4081 aagataattt ataaggtaat gtatcaagaa gttaaggtta agatagatta tactcaactt
     4141 ggaaaagtgc aaaatgagtt aatgaatttg gggtatttta taaaagatac tgtatatgag
     4201 gataatgttg aaatagtagt atattcaaga ttagaagatg tagagaaatt atcagaaaaa
     4261 atgattgata taacaagtgg aacaggaaaa atagttttag gagaggaatt ttatttgtct
     4321 gaacaaaatg gagaaatttt aatataatct aaaaggttat tagaatagtt aatacctcaa
     4381 atagccaatt agtattttta agtgaaaagc cattaaattg atttaatcta aatcaattta
     4441 atggcttttt atcggatttt gcacagaatc ctttttttac ttcaaataaa ccgactaaaa
     4501 gtaaaaatat cccaaatatt ttttttaata tatctgaaga cagataatta gctaatagtg
     4561 aaccaaatac agctcctaaa accccaaaca cagctatagg tataaccaat ttaaaaatta
     4621 catttttatt ttttatatgt atagcaagtg ctataagtgt catagggata gatgaaagta
     4681 aatttacgct ttgtgctatt ttagtgtcta tgccagcaag taaaacgagt gcaggtataa
     4741 ggattgttcc tccacccatt cccattcctc caataattcc tgcaaaaaat ccaattagag
     4801 caaataacat taaaacacca tccttaatgc tgcaattatc ataattattc caaaagaaat
     4861 tctaagaaac tttccagtaa ccttatttag taatttagct cctataatac caccaagaat
     4921 acttccaact gcaactttaa ttgttaagtt aacatcataa gtacctttag atacatataa
     4981 aacagaactt gctgtcgtta agaatattat tatagaaaga gcagttgcat gagatttatg
     5041 ttcttctacc ttaacgatgt catttaatat tggaactaaa agagtacctc ctccagaacc
     5101 aaaaactcca tttataaatc ctgtaaaaac tccaattatc gtatttttta agttaaaatc
     5161 aaagtatttt ttctttaaat catcagtttt tttcataaaa atcaccttct gaaatagttt
     5221 taccaaaata ggcaaattat atttatataa aataagatta aatataatct ttcatgtttg
     5281 tttaattttg cataaaaaaa aacatattaa aacaacatat taatatatgg tataatatat
     5341 taaaacaaag tagcaaattt gagaggagat aacaatgtca aatataaaaa tacaaataga
     5401 caaaactgta gaatggctta taaataaggt taatgaggca aatgcaaaag gattaattgt
     5461 tggtgtatct ggaggaattg attcggcagt agttgctaat ttaattaaaa aggcatttcc
     5521 agaaaactct atgggagtta taatgagcat aaaaagtaat cctcaagata gagaagatgc
     5581 acttaaggtt atagagggat gtgatataga ataccttgat ttagacctta tagaaccaca
     5641 aagtgctata ttagacatgg tagtaggaaa tttaaaagat aaacatttat atagagaaga
     5701 atatttaaag atgacagatg caaacttaag agcaagagta agaatgagta caatttatac
     5761 aattgctaac aatctaggat atctggttgt tggtacagac aatgctgcag aaatacacac
     5821 aggatatttt actaaatttg gtgatggtgg agttgatatt ttacctattg caaatttaac
     5881 taaaggagag gtgtatgaat gggcaaaaga gcttggtgtt catgaagatt taataaacaa
     5941 agctccttca gcaggtcttt gggaaggtca aacagatgaa gatgaaatgg gaactactta
     6001 caatatgata gatgctgtgt tagaaggtag attggatgaa gttcctaaaa gagaccaaga
     6061 gataattgaa agacttcata gattaagtga acacaagaga aaaacgcctg cacaacctcc
     6121 taagttctaa tttactattt ataagatttg tgataaaatt tacaagtgat gaaaattaga
     6181 ataattaatt gtacgtatta aggagtggaa atatgggacg tataggtaat ataattaata
     6241 gaaaaggtaa acaagatgct caaagagcaa agatatttac taaacatgct agagcaatag
     6301 cagttgcagc taaggaaggt ggagcagacc cagagtacaa tgcagcgtta aaaacagcta
     6361 tagaaaaagc taaggcagat aatatgccaa atgataatat agatagagct atcgctaaag
     6421 gtgctggagc aggtgctgga gaagactatg aaactatagt ttatgaagga tatggacctg
     6481 gtggagttgc tgttatagta gaaactttaa ctgacaacaa aaacagaact gctggtaacg
     6541 taagatacta ttttgacaaa aacggaggaa acttaggaac tagtggatgt gtgtctttta
     6601 tgtttgataa aaaaggacaa atattagttg gtttaggaga tggagtttca gaagaagaat
     6661 tgatggatgt tgcattagaa gcaggagctg aagatttcat aacagaagaa gatggttatg
     6721 aaataataac tacaccagaa gatttttcta gtgttcgtga tgagttaaaa gctaaaggat
     6781 atgagtttat atctgctgat gtgaagatga tacctcaaac tacaactgta ttgactgaag
     6841 aatctcattt aaaaatgatg aataaattag ttgatatgct tgaagaagat gatgatgttc
     6901 aagatatata tcataactgg gaagtagaat aaatagtata agcatattga aatttataag
     6961 tattgaatca attttaacat gtgataaatt ttatagaata agaaacacta aaatagacat
     7021 acgcacctct aacctatatt tgcataataa tatgtaagca taggtaaggg gtgtttttat
     7081 atttataggt taagaaattt aaagtaaatt ttgagctgga ctcgattgtc tataaataat
     7141 tgatgggtat ataacttgtt gctgaatacc atttatacgc ccagttactg tatcaataat
     7201 catcctaaga ctacgttctg ctgtctcttc catttttaaa tctataactg tcaaaggagg
     7261 aatacttctt gccattagtc gtgaaggtcc attacttgct gcaaatattt gaatatcctc
     7321 tccaattaca attcccgatt catgaaatgc attcatcata ccaagagcta ccacatcatg
     7381 attacaaaaa attacttttt ttagtgaatt ttttgcaagc attttttgag caatatcata
     7441 tccactatct attttattag aacaataata tatagaatct gatagatgta ttccatgttc
     7501 tttacatgtt tttaaaaaag atttacccct taaagtcata catgtaaagg aagttgggtt
     7561 gaatacaaca gcaatatcat ttttaccatt ttgaatagca tgtaaagctg ctatacgacc
     7621 agtttcctca ttatcaatag atacacttga aaaaccaggt atttcacgat ttacaacaac
     7681 tacaggaatt ttaggtttat tttttactag atattctata tcatcagcat tgatacctgt
     7741 taaaacaatt ccatcataat aattatttgc aaaaaagtat tcatcatcac atagatgacc
     7801 aactttgtaa ggtcgtatga tgatatttat gtttaaatgt tctaaagaaa ttatgtggtt
     7861 tattgcttga agtatattgg ttgatgccaa ctcaaatccc tcatcctgcc aataaaaagc
     7921 tattttaata ttattatgtt taataggagt agagcgttta tatccaagct tatcagctga
     7981 atttaatata agctcttgtg tatgtagcgg aatcctgcgt tcatttcctt taccacttaa
     8041 gacgtacgag acagttgctg aagaaagacc acagtctttt gcaatatctt tgattgttgc
     8101 catgataaaa tcctccttaa atagttgctt aaatttgctt ataccaataa tcttaacata
     8161 tattcaacta aagaacaata ttctacaagg tgcatatttt acagaattag aataaataaa
     8221 tttaaaaaaa cttcttactt atgttgacat aatttagttt ataggattat aatatgctta
     8281 aataagctta ttattaactt aaattaagca aagttaagca ggaacatgca atgctagctt
     8341 gcaatgtgac tgtaaagggg gaaaaggtat gagtaaggta aatatatttg aagttggtcc
     8401 tagagatgga tttcaaaacc tgaaagagtt tttagaaact gataaaaagc ttaagattat
     8461 tgatggtctt attgcttcag ggattaaaca acttgaaatt agttcatttg taagcccaaa
     8521 agcaatacct cagatgaaag atgcaaaaga agtagcaact tattgtgtag aaaaatatcc
     8581 tgatgtgaaa ctttatgcat tagttccaaa tttatacggt gctaaagttg catgggagtg
     8641 tggtataaga gatatatcct atgttatatc tttgagtgaa actcataata aaaaaaatat
     8701 aaatcgtacc catgaagagt ctattgatga gcttaaaaaa ataatgaata cttatccaga
     8761 catgaatata tgtattggaa tggctactgt atttggatgt ccttttgaag gtttaccaaa
     8821 aattgaagat gccataagat ttgctaaacg cctttgggaa aacggtatca gggagatgaa
     8881 tctagcagat acaataggga ttgctgaccc taagcaagta agagaaacta ttagtgcatt
     8941 agttgaagct ttaccagagt gcagatggca ggtacatatt catgatacta gaaatatggg
     9001 aatggttaat actcttgtgg ctattgaatc tggaattact actgttcagt ctacacttgg
     9061 aggattagga ggatgcccat ttgctcctgg agcatctggc aatactgcaa ctgaagattt
     9121 agtatatatg cttgaacgta tggggtatga tacaggagtt gattttgtta aacttcttga
     9181 attatcaaag tatcagaaga gttttgtaaa tggagtatat agtggtcatc atgtaaatat
     9241 aaagtctgat agttgtaatt gttagttcta ttgattaatc gattaaaaaa atatgttgat
     9301 taaaaaaata tgctgattgg taaaatagat ttattgataa aaaatataaa ttataaaata
     9361 cattatctaa taaaacaaat aaaaaaattg agggggatta gtatggatat tatagcttta
     9421 cttttatttt taggagttat tattattgca tttgtacgta agaataatgc aggtattttg
     9481 gctctagcta ttggtgtcat agctgttaga atttttggaa tggatgataa agaactttat
     9541 ggagctataa gcaactcaat gtttactaca cttgttggta taacactact ctttgcaata
     9601 gtgaactcaa caggagcatt aaagcttgtt gcagaaaaaa ttgtagctgc ttctggtaaa
     9661 cgtgtttggc ttatacctat agcagttttt atagcaggat ttgttgttgc tggtgttgga
     9721 cctggggcaa ttccagcact tgcaattatc ccagcaatgg ctgttcctgt agccataacg
     9781 gttggttata atcctgtaat gcttgcactt ataggtgaat gtggattaat ggcaggtcgt
     9841 atgactccta ttactccaga aggtcaaatt ataacaaccg ttgcagaagg ggttggaatt
     9901 gaaaatgtta tgcctactat cttagcctgt caaactcttt ctacaattgt attttcaata
     9961 gtattgttta taattttcaa aggatataaa cttaaaaaac ctataaatgt tatagatagt
    10021 aagcaaatag aaaaattcaa tataaagcag ataatttctc taataagcat agtagttatg
    10081 attgctttta tcataatttt tgatatgaat gttgggcttg cagcttttgc agtttcagct
    10141 gtacttattt ttttcaatat tgctgatgaa ggagaatgta tcaaatcaat tccatggagc
    10201 acgatagtaa tggttcttgg agtaggtgca atgatgacaa tcgtagatgc agcaggaggt
    10261 attgacttga tgagtaatgc attatcatca ctgatgaata gtaaaacagc tactccaatt
    10321 atgagtattt cagcaggact tatgtctatg gttagttctg ctttagcagt agtttatcca
    10381 actatgatgc ctatgtgtgt tgatatagct aaggcagttg gaggagtaga cccactagca
    10441 cttattgctg cagttggtgt tggaggttct cttgctggtg taagcccact ttctactggt
    10501 ggggcattga ttttagcagc tatgggttca agtaagaaag actttaataa ggaagaacaa
    10561 aataaggttt ttgtacagct tttcattatg agtgcagttg gcttattggt tattgcagta
    10621 gtatcaatat tatcatttaa tgcaataaca catttaatga actaattaga ataactgaaa
    10681 ataaatcatt aaatttaact tttaatatta atcaatataa tataatttgg aggggaagtt
    10741 atgaaaaaag gagcattaag caatataaag gtacttgacc ttacaagagt tcttgcaggt
    10801 ccatattgta caatgatgtt ggcggatttt ggagctgatg ttataaaaat agagatgcca
    10861 agaaaaggtg atgatacaag aggttttgga ccttttgtaa atggagagag tttatactat
    10921 gcaaatataa atagaaataa aaaaggtatc actctaaacc ttaaatcaga agaaggaaaa
    10981 aatatatttt tagaaatggt aaaacatgct gatgttgtag tagaaaatta cagaccaggt
    11041 gtaatggaaa agttaggtct gggttatgat gagttggcta aagttaacaa tcaaataatt
    11101 tatggagctg tatcaggatt tggatgttat ggaccatatt cagaacgtcc aggttatgat
    11161 attattgcac aggcaatggg tggtcttatg agtataacag ggcaagaagg aggagaacca
    11221 acgagagttg gtaatgctat gggtgatgta ctaggtggaa tgaatttaac tattggtata
    11281 ctcacagcac tcaacgctag aaaaataata ggaaaaggac aaagagtaga tgtttccctc
    11341 gttgattctg ttgtatcgtc tctcgaaact ggtatacaga gatactttga ttcaggacaa
    11401 cctgaactta tgggtaatag atatgcttca gcctatcctt atgactcttt taaggcaagt
    11461 gatggaagtt ttgtaatagg ctgtggtaat gacaaacttt ttgaaaagtt atgtaaaaaa
    11521 gttcttttta gagaagacct tttaatagat gagagattta aaacaaatct taatcgttgt
    11581 gaacattaca aggctcttaa accagaaata gaaaaatggt ctattaagca tacaataaaa
    11641 gaagcagttg acttaatatc agaggctgga gttcctgctg ctcctatcta taatcttgat
    11701 tgtgttacaa cagatgaaca tatagcaaaa gcaagagaaa tgattgtaga tattagtcat
    11761 cctattatag gaaatatgaa agtcaatgga aatccagtta agttgatgac aacaaaagct
    11821 aaaattgata tgccagcacc atctctaggg gaaagtaacg aggagattta taatggttgg
    11881 cttggttttg atagtgataa aataaaagat ttaaaagaaa atggagttat ttgattaaaa
    11941 aatagctaaa cacacttgtg actttagtca ggggaggttc agttagaata atatcaaaaa
    12001 atattaaatc aatactgtaa atcaaatata gaattgtcag aagcatttaa gatgggaaaa
    12061 gctacttaga cattgagtct ttgtggcttt tcctattttc attaagaatt ttatattatc
    12121 agaatagata tgtactaaac taaagtatta acaatttaaa ttaatagaaa ataaactacc
    12181 taattatgtt gaataaagac tactttagtg aaaataaact tatagagatg ctatttaaat
    12241 tattttaatg gaaatatcaa aaatgagact gcattctcaa aaatgagact gcgtttttta
    12301 agtattttct cgaaaatgag acaaaaatat tgttttatgg gttttattga agaaaaattc
    12361 ttctgtgaat tacaatttaa tcaattttaa agttgaaaat tattaaaaat ttagtgaaat
    12421 ttatgtatat ttcgtttatt ttattaaaaa taacaatttt ttactaaaaa taaagaactt
    12481 caatggtgat tggcatagta cttgctattt tatattaaca agaaatgtag aaaaaataac
    12541 aatgtataat ggggggaata tgatggaatc tgtaatggaa aatttgaaca atcttaaggt
    12601 ggaggttaag gacaaagtct gtgttattac tataaataga cctaaagctt taaatgctct
    12661 taatagtgac actcttaggg aactatcaca agttattgat gtagtatcag aaaatgaggc
    12721 aatattagga gttattatta ctggagaagg taaagttttt gtagccggtg ctgatatacg
    12781 ccagatgcaa aactataaaa gtgaggaagg cagaaaatat gcaggttatg ctcagggagt
    12841 ttttgataaa attgaagctc ttgaaaaaac agtaatagca gcagttaatg gatatgcatt
    12901 aggtggtgga tgtgaacttg ctatgagttg tgatattaga attgcatcag aaaaggctat
    12961 atttggacaa cctgaagtta atttaggagt tattccatgt tttggtggaa ctcaaagatt
    13021 atcaagactt gttggaactg gaatagctaa agagttaatt tttacaggga gacaagtaaa
    13081 tgcagaagaa gctaaatcta ttgggcttat taataaagtg gttccaagtg atttactttt
    13141 agaagagtct atgaagatga tgaaccaaat agttgaaaaa gcgccaatag caataagata
    13201 tgcaaaagtt gttattaaca aagggataga tatggattta aagaatgctc ttgaactaga
    13261 gaaagatatt gcaggtttaa cttttgctac aagagataag caagaaggaa tgaatgcatt
    13321 tatagaaaag agaaagccag tttttgaaaa taagtagcta ttataactaa aattggaaca
    13381 atgtagaata tattcaaaat ctaaatttcg tgaaaaaata catatagttt aattttaaaa
    13441 ggagttaatt tatgaatacg ggagtaatta taagtttagt agggattatc atagctctat
    13501 ctcttctagt tgtaatggtt atgaagggaa taaatatttt tattatagca attgtatgtt
    13561 catcattagt tgctataaca ggaagcctaa atgtgtatga tgcacttaaa gtggattata
    13621 tgacagggtt tgttggattt cttcaggcaa atttctttat tttcctaaca gggacattaa
    13681 tgggaaaaat aatggagatt actggtggag caaaatctat tgctaagatg attgtaagat
    13741 ggattgggaa ggataaagca ctactttcta ttccaatagc ttgtggaata ttagcctatg
    13801 gtggagtaag tgttttcgtt gtaagttttg cagtgtttcc gatagcttta gaaattttta
    13861 aagaagctga tttgccacga agatttatac cagcagcttt gacttttgga tgctcaactt
    13921 ttgctatggt tgcaccaggg gcaccacaaa ttcagaatat tgttccagca tcaacattag
    13981 ggacagatat tatggctgga gcagtaaatg gttttatatc atgtgcagta atgtttatag
    14041 ttggaagtac aattttgtac aaaatggttt caaaagaaaa agccaatggt ggtcatttta
    14101 tagcacatga atcagatata tttgatgaag cagaagcaac taattctaag agagaaaatg
    14161 gtcccaatgg tgtaattgcc ttaattccat tgatagtgtc aattttaata attaatgtaa
    14221 aagttaatgg aaaagcgata gtaccaattg aggtgggagt atttattgga gctttattag
    14281 tatatttatt gttaaataaa tatcaagata atactaaaat agttggacat gttggtgatg
    14341 catgtaaaac tacagtagta gcaatatgta atacttgtgc tgtagttgca tttggttcag
    14401 tagtaaaatc agcagttggt tttgacttca tagttaatgc tatgactaat attcctggtc
    14461 ctcctattgc aggggctgca gttggaacta cagttattgc aggtatttgt gggtcagctt
    14521 caggtggact aggaattgca gctccacttc ttggaccagt atttttagcc aagggtgttt
    14581 ccgctgcagc attaactagg actatggcaa tttcatcagc agcattagat tcacttccac
    14641 acaatggata tattgttact gtaacaaatg gtctttgtaa agaaacacat aaggatgcct
    14701 atatgccaat attctgggta actgttttaa ccccatttat tggaaccata gtagcagtcc
    14761 tactgtttac aatgttcccg ggattgccat aagagaaaag ataaaaggta taaattatat
    14821 tttgatgtta taaaatcaat tttcaaaata tatacaataa atttcatgtt ttaatactgt
    14881 aaatatgtat ttaaaataac aaattgacca tataaggagg aattgaaagt gttaaataaa
    14941 ccattagagg gagttaaggt tattgaccta acgtattttg tagcaggtcc agggacttct
    15001 aaaatattag ctgactgggg tgctgacgtt attaaggtag agccaagctt tggagaccca
    15061 ggaagaaaga caggggcaac aatgacaatg ccaatagatg attataataa tcctttttac
    15121 agcacatata attcaaataa aagaggtttg tctataaatc ttaagagtga aactggaatt
    15181 gaaattatgg ataagctttt aagcgaagca aacgtatttg tttcaagtta tagaacagga
    15241 gcattaaaaa gactaggtct tgattatgaa tcattaagta aaaagcatcc acaccttatc
    15301 tggggtcaga taaatggttt tggcgatttt ggacctgcta aggataatgc aggatttgat
    15361 acagttgcct tttgggcaag aagtggggct atgcttgata tagcagaaaa agatacaagt
    15421 ccaataaatc cacctatagc ctttggagat gcaacaactt cttgtagttt atctggagga
    15481 atatgtgcag ctttgtacca gcaagctaag actggaaaag gacaaaaagt aatggcatct
    15541 ttatttgggc aagcaatatg gaatgcatca tctttattag catctacaca gtttagtgat
    15601 gagtatccaa aaactagaaa aaatgctatt tcaccagtaa taaattctta tcgttgtaag
    15661 gatggaaagt ggatattctt aagtatttta gagcatgaaa gatattttga ggcactttgt
    15721 agattatttg gaagagaaga cttaataaaa gaagagaaat ttgcatcttc agtagaaagt
    15781 aagaaaaatg ctacagaact tattaatatt ttagatggtg aatttgcaaa gtttactcaa
    15841 aatgagatgg ttgaaaaact tactgctgct gatatagctc atgaaaaaat tcaacatgtt
    15901 aatgatgtag tgactgatga acaggctatt gctaataact atatatatga acatacaagt
    15961 aaagatggaa ataagacaat gcttgcatct actccagtta aatttggaaa tattgaagtt
    16021 aacatgactt gtgatgctcc acttatagga gaacattcag atgagatatt gagagaactt
    16081 ggatacagtg attctgatat agaggctcta attgaatctg gaattgtaac aatgaataaa
    16141 gaagcatgtg aaatatgtta ataaacatgt gaagtatgtt aataaatagg agggaatttt
    16201 atggatttta gattaacaga agcacaatta atgcttcaaa gagtagcaaa agaatttgca
    16261 gagaatgaaa tagcaccaat agctgctgaa acagataaaa caggtatttt tccaagggag
    16321 ctttttagca aaatggctaa aataggattt aatggaattg gaacacctgt agagtatagt
    16381 ggttctggtg gggcagatat agaaaaggta attgttgtta ctgagattgc caaaaaatgt
    16441 gcagcatctg cagcaatatt atcaatacac acaatatatg ctcaagctat tttgaaattt
    16501 ggtactgagg aacaaaagaa aaaatacctt ccaatgatgg ctgaaggtgg gtgtgtaggt
    16561 gcttttgcct taaccgaacc taatgctggt tcagatgctg cgagagctgc aacaactgca
    16621 attattgatg aagaaactga tgaatatgtt ttaaatggaa ctaagtgttt tatttctggt
    16681 ggaggtcaag cagaatcatt aataatattt gcattgacag acccatcaaa gggaataaag
    16741 ggaatgtctg ctatcattgt cgacaaaggt acgccaggtt tttcaatagg aaaaattgaa
    16801 gaaaaaatgg gtattcatgg ttcagaaact gcagagttaa tatttgataa ctgtagagtt
    16861 ccaaagtcta acttattagg aaaagaaggt aaaggattta atatagctat gacttgttta
    16921 gatggagcaa gaattggagt tggagctcaa gctgtaggaa ttgctgaagg ggctttagaa
    16981 gaaagtatca aatattctaa agaaagagtc cagtttggca agccaatttc agctttgcaa
    17041 ggtattcaat ggtatatagc agatatggcg acaatggtgg aatcagcaaa attattagta
    17101 tattatgctg cagatttgaa agctagagga gaaaaacaca ctaaagaagc tgctatggca
    17161 aaatacaatg cgtcacgtac tgcaagagag gttacaaatt tagcccttca aatccatggt
    17221 ggatatggat atatgaagga ttatccatta gagagaatgt acagagatgc caaaataaca
    17281 gaaatttacg aaggtacttc agaaatacac aaagttgtta tttcaagagc agtactagga
    17341 taggaggaaa agaatgaata tagttgtttg cttaaagcaa gttccagata ctaatgaagt
    17401 taaaataaat aaagagacag gtactctaat aagagatggt gtaccaagta taatcaatcc
    17461 agatgataga aatgctttag aagaagctct aaaaatgaaa gatgaactag gagcagtgat
    17521 taaggttata agcatgggac ctcctcaagc taaaagtgct ttaaaagaag ctttggcaat
    17581 gggagctgat gaagcttatt taatctcaga tagagctttt ggtggttcag atacttgggc
    17641 tacatctaca attattgctg ctgctataga gaaggttgga aagtatgatg taatattctg
    17701 cggaagacaa gctatagatg gagatacagc tcaggttgga ccagaggttg cagaattttt
    17761 agggatacca caagttactt atgcgaaaga agtaaaggtt caagatgaca aattactagt
    17821 aactcgttat acagagacag gggattattt aatagaagca aagatgccag ttttattaac
    17881 tgctataaaa gagttaaaca atccaagata tccaagtgtc aagggaatct tagaagctta
    17941 taataatgga gatgcaaaga ttactgtatt aacacttgca gatttagatg ttgatacaac
    18001 tcaaattgga ttaaagggtt cacctacaaa cgtttataag tcttttgtac cagttaaaga
    18061 caagcataat gaaataatag aaggtataaa taaaaaagaa aaagctgaga aactaataga
    18121 aatactattc gatttgaaac tagtatagga gtgttaagat gatgagagca aaagttaatc
    18181 aaggtataaa tttaaatgat tataatggtg tttgggtaat aggagagcaa agggaaggta
    18241 aaattaatcc tgttacgata gaacttattg gtgaaggaag aaagcttgct gaccaattag
    18301 gaaaagagct tgcagttgtg atagctggat atgaagtaga gaaagaagtg aaggaattac
    18361 ttcactatag tgttgataaa gtatattaca tcaatgaccc tcttcttaaa gatttcacta
    18421 ctgatggata tgcaatttca attgcaaatt taatcgaaag aaaaaagcca gaggttgtat
    18481 tggttggtgc tacttctata ggaagagata tagcgcctag aattgcaggt aaggttggaa
    18541 caggtctaac tgctgactgt acaaaacttg aaatagattc aacagataat aagttattac
    18601 aaacaagacc agcatttggt ggaaatttaa tggccactat tgtttgtcca aaaaatagac
    18661 cacagatgtc aacagttcgt ccaggagtta tggcaaaagc tgtaagaaac gaatcagaga
    18721 ctggaatttt agaagttgtt actccagaac ttactgaaaa aatgattaga actagattag
    18781 tagagatact tccacaagaa aagaaatctg taaatctaac tgatgctaga ataatagtat
    18841 caggaggaag aggattaaaa agagcagaag gatttgagct tataaaagaa ttggctgata
    18901 aattgggggc agagattggt gcttcaagag cagcagtaga ttcagggtgg atagaacatt
    18961 ctcatcaagt gggacaaaca ggaactactg ttagaccaga actatacatt gcatgtggaa
    19021 tatctggagc aatacaacat ttagcaggta tgagtgattc taaatatata gttgctataa
    19081 ataaagatgc aaaagcccct atttttagta tatgtgacta tggaatagta ggagatttat
    19141 atgaaattat acctgaaatg atagaatcat taaataggta acttttagaa aacattgaat
    19201 atgtagaatg ataagtctta taatattgta ttgtaagact tattattttt gctgaaggtt
    19261 atagtgggga gatgaaacaa tgaaagagca gtggtataag gatatatttg caagagtatt
    19321 atctatgact gatgatggtt ttattgttgt aaatagaagt ggagtaataa tagatattaa
    19381 tgataaatat tgtgactttt taggaaaaga aagaaaagat ataataggac aaaatataca
    19441 aagtattata ccaaatacaa aaatgctaga tgttatgaaa aataagtatt gtgaagaagg
    19501 agctatacat cattattcag gtggaaatac aaaagaaaaa agtgtaatag taagtaggtc
    19561 ttatgtggaa aatgacaatg gagaagtagt tgcaggagta gctcaagtta aatttagatt
    19621 gcaatcattt gatgtagcta aaaagttaat gtcagaatat atggagctcc aatattataa
    19681 agagcagttt aaggataact gtggttttga caagctcata ggtgaaaata gagacttcat
    19741 agaacttaag aaaacaggtg tgaaagcttc taaaacaaac tttccagtac ttttaacggg
    19801 tgaaacaggt acaggaaaag aagtctttgc tagagcaatt cacaataata gcagtaggtc
    19861 agataaacct atggttagta taaactgcgc tgcaatacca gaagaattat tagagtcaga
    19921 gctatttggc tatgacgaag gagcttttac aggagcaaaa aagggtggta aaaaaggtaa
    19981 atttttagtt gcgaataatg gtacaatctt tttagacgag ataggtgaca tgcctttgac
    20041 catgcaagca aaacttttaa gagttcttca ggaaagtgag atagaaccag tgggaggtct
    20101 taaaactata aagatagatg taagagtaat ctctgccaca agaaagaatt taagtaaaat
    20161 ggttgaagag ggattattta gagaagacct atactataga ttaaatgtaa taaacattca
    20221 tatgatggaa ttgaaggaca ggcaagatga tattttattg ctagcaaatt atatattaaa
    20281 caaattaaat gttgaataca aggaattgaa ggttttaagt gataaggtta aaaattgttt
    20341 tattaactat acttggccgg gaaatataag agaactacaa aatgtaataa aaagtgccta
    20401 tgctgtaagt gatgatatgg tcattatgat gtgtgacctt ccatctaaga tggataatat
    20461 cagcagagta gctcaatgta atgtggatag caattgttca attcatgaaa tggttgagaa
    20521 ttatgaaaag agcttaatta ttgatgtgtt aaggaagtat aattggaaat gttctaaggc
    20581 agcagaggtt atgggaatac acaagagtct tttatataag aaaataaaaa agtatgaaat
    20641 tgaattaaat aattaagata aattgaatta aggcaatgct aaaaaaacgc ccttattcaa
    20701 agcgaactgt ataaactgtt ttatgcagtt aaaacgtgta aaagtagatg tgaagtacta
    20761 atgtcaatca ttagtacttt tttattatat ttataattac tatctatatt tcagtatctt
    20821 ttgatatcta agattattat gtttaattta ggatataaca aaaccctctt agttatggac
    20881 agttttttat attttaactg tctactaaga ggggatagtt tagtttaaat ttagagtaaa
    20941 ttttatctag catttataaa aaatattttg aatagctttt ttgttattta atcataattt
    21001 tctacttctt tatcaagttc tttgccacaa gaatcacact tatatatagc attgtatccg
    21061 taatcatatt catcaactat tttcttttgt ctaaatacac caccacactc acataggaaa
    21121 ccaattttta taagtgtaac gataaattgt gattttataa attttatatc attacattta
    21181 tcgttagtgt aaaatgtata aatataagag ttatcgcact catctcttaa ttcaaatctt
    21241 tcaatatatg tgttattttt taattcctca aattcttctt tagttaaata tgatttttgt
    21301 tgcaattcat gtaaacgctt aatttggtcc attatttata tcctcccaat aattttagta
    21361 ttttaagctt agataaggaa tctaagtttt attaaattta tcccaaggaa ttatttaaat
    21421 catatttagt tttattaatt acaacatata taaattacac gaaaataaaa ctaattgtaa
    21481 aaataatatc ctgtgaaaac ctaaactact aaccccttac taacccgaaa actaaaaaaa
    21541 gaaaatatat ccaaatataa gtgatatata aataaagatg tttcatataa atttaacttt
    21601 aaatattctg a
//
LOCUS       DAEPKC010000068        21375 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.068, whole genome shotgun sequence.
ACCESSION   DAEPKC010000068 DAEPKC010000000
VERSION     DAEPKC010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21375)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21375)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21375
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.068"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            409..4542
                     /locus_tag="KR294_002548"
     CDS             409..4542
                     /locus_tag="KR294_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF11 domain-containing protein"
                     /protein_id="HBH0240618.1"
                     /translation="MATVSGQIVFDRNRSATIDSGDSGIANIPVVLQDIATGVRLVVL
                     TDASGNYVFTNVPNGNYRIVEAFGTTGGVPTPGNFATAIVGPVPIAEMPPISPPIGST
                     NLDGTTPNTLLITVAGSDITNQNILNGPVIYTPIENILDSCVSVSNINLITDADNGTF
                     GFFPPGTPSNTGPEIEPYPNVTPDFTYVVPDPTKFTPLDGEYTVQNIMTNAMSNVIGA
                     WWRIADHTTGNETGRMMVVNGFNPGAVFFKSTVQVTPNTNYLFSTWILNLFKVTGYPP
                     PQLGVRIFDQNNNILYQATLGAQIPVNTNAPEWKEVGTVINSQNNNQLTVEFFSEGES
                     AIGNDYAIDDVSLREIAVPTFTPIKTSNTETANVGDIITYTVTLDNTCDSPLTNVFFR
                     DLIPNGLEFIPGTVTVDGVSVPGVDPNTGFSLPDIGGGTGVEVTFDVVVESIPNPNPT
                     NNIANIDYSYTPVEGGIPNDFSVDSNPVPVEVISADIEVTKLSEPTIVNPGEELIYTI
                     KVVNNGPFPSENVVLTDDVPASIINPEYSLDGGVTFQPWTGSLNIGTLEVGETRVIII
                     RGIVNPSTVGIITNTAVVSSTTADPNLNNNTSTIETEVNLLADILVMKTAEPNSAVPG
                     TLLRYTIQVENLGPANAENVILNDDIPASIINPEYSLDGGASFQPWNGSLNIGTLNSG
                     ISLTVLIQGTVSLNSSEYIVNTATVSSTTPDPDLSNNISTIITPVNPQAGISIIKVAD
                     EDVAVPGEEFVYTIEIFNEGPSNATNVVLTDDIPDVILNPEYSLDGGATFQPWNGSLN
                     IGTVAPGQLIRIIIKGLVSSTATGDITNTAEVSADVPEPVTDSSTVTTPIVPSADIEV
                     IKTSNMDTAVPEETFSYTITVTNLGPSAAQSIVLTDDIPDVILNPEYSLDGGVTFQPW
                     NGNLSIGTLDAGEIRSIIIRGTVSQTAVGTIINTATISSPTPDPNPDNNTSTDETDIS
                     PLADISVIKGNEPVAIPGGRFIYGIEIANAGPSFAENVTLTDNIPASILNPEYSIDNG
                     VTFQPWNGSLNIGTLDAGEIRNIIIRGTVSQTAIGTIINTATVSSTTPDPNLNNNTST
                     SEAEVSSSADISVVKRSNQTVVVPGDVLDYTIEVRNAGPSTAQNVTLTDNIPASILSP
                     EYSIDNGVTFQPWNGSLSIGTLDAGEIRNIIIRGIVSQTAIGTIINTATVSSTTPDPN
                     PDNNTSTSEIDISSSADISVIKLANKTEACVGEQIDFVIVVSNAGPENAQNVTLIDNV
                     SDKLKKAVFSLDRGVSFQPWTGSLNIGTLPAGTLRVIILRGIIKSTCLDRLTNIAEVT
                     STTPDSNLNNNISRVQVEIKQFCCNDCGCKDCCCNCCCNDCGCKNCCCNCCKNDFWC"
     gene            4999..5346
                     /locus_tag="KR294_002549"
     CDS             4999..5346
                     /locus_tag="KR294_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HBH0240619.1"
                     /translation="MHENKKNLLDGSLAQYNDTAVPKIPVFAGNDITSEVYYFKPNQV
                     LNAHRHPNGEQIFVFLKGEGKMKLGEHECDVKNGDTVFVPTGEWHEITNGSNEEMVAV
                     QITKINAGAEYRG"
     gene            complement(5496..6545)
                     /locus_tag="KR294_002550"
     CDS             complement(5496..6545)
                     /locus_tag="KR294_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBH0240620.1"
                     /translation="MFKKIVAIASSIIVSTICLTGCDFNSNDKKDESSSSKNLDKVTI
                     AEVTHSVFYAPQYAAITKGFFEDEGIKIDLINTQGADKTMAALISGEANVGLMGPEAS
                     IYVYNQNKNDYAVNFAQLTKRDGSFLVARKKMPNFSYNDLKGTEILGGRKGGVPLMTF
                     EYVLKEKGLTIGENLKAGNVNVRTDVQFGVMAGAFAGGEGDFTTAFEPTATAMEKEGS
                     GYIVTSIGKDSGEIPFTAYSTTRSYMKNNKDLIQRFTNAVYKGQLWIQQASSKEVAKA
                     MQPFFEDISLEDLTTVVDRYKSIDAWSQNPVLKEEGLKKLMTVMKEAKELDKEAPYKD
                     IVNTEFANNAIKNIK"
     gene            6931..7665
                     /locus_tag="KR294_002551"
     CDS             6931..7665
                     /locus_tag="KR294_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBH0240621.1"
                     /translation="MKQNKYDDDRFFNKYSKMERSTNGLAGAGEWHVLKKMLPDFKGK
                     RVLDLGCGFGWHCQYAVENGAISAVGVDISEKMLKEARNKTQLDNINYICMPIEDINF
                     PKDSFDVVISSLAFHYIQSFEDICKNISNCLSNKGNFVFSVEHPIFTAYGSQEWYCDK
                     DGNNLHWPVDRYFEEGVRRSNFLGEEVIKYHKTLTTYLNALMKTGFEILEIIEPQPEE
                     KLLDTIPDMKDELRRPMMLLVSAKKR"
     gene            complement(7808..8299)
                     /locus_tag="KR294_002552"
     CDS             complement(7808..8299)
                     /locus_tag="KR294_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HBH0240622.1"
                     /translation="MNNQQQEVYKKLDELSIPYEAVNHPPVYTIEEMEELKTLHMEFV
                     VKNLFLRDAKGKEHFLVVLGKDKKADLKDIRQQIDSKPLSFASEERLQKYLKLTKGAV
                     TPFGILNDKEAVVKVVFDKDLLKMDKIGIHPNDNTATVFLKFEDMKKLIEENGNEIYY
                     VEV"
     gene            8648..9031
                     /locus_tag="KR294_002553"
     CDS             8648..9031
                     /locus_tag="KR294_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240623.1"
                     /translation="MSTDKVVGIIDEETAELAGIEYTGKIYASSGVIKHIKKKHRCQL
                     SKDIFNDIIDTIKMVLKSPEYIGSHPKKPGKSVEFIKKIDDYILVATELDTKKGYLYV
                     SSMYAIKEAKLESRVNSGRVKQYDG"
     gene            9539..9922
                     /locus_tag="KR294_002554"
     CDS             9539..9922
                     /locus_tag="KR294_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBH0240624.1"
                     /translation="MNLSKKIEDKRKAKQRAEKVKKAKIATAGVVLGAVTGAVSGVLL
                     APKSGKETREDIKDASQQIAEKINMKTVDVKGKVSEKLEDKKGNFIESKKKIKKYIDN
                     KKSVENSSEEDKIIDIVEPVSVTEE"
     gene            9924..10274
                     /locus_tag="KR294_002555"
     CDS             9924..10274
                     /locus_tag="KR294_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240625.1"
                     /translation="MDNTITINISIIYVLLAILACIALVYLIIVLVKLHKILNNVGTM
                     LNENTQNINTTLNNLPNVVETFGEVGENMKDVTEVVTEVTADFLVTKDSVKSNMDVIV
                     DILTIIKNIFVDKK"
     gene            complement(10375..10833)
                     /locus_tag="KR294_002556"
     CDS             complement(10375..10833)
                     /locus_tag="KR294_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240626.1"
                     /translation="MIRTKVVELIATVCRENKPHKWVDENYTPYDKSGKVELMSIEDL
                     NELISSSGRADFLYSSRLQKLLNEVYINQSRASYISGCGLFWSSYWDILEEKFEEWLY
                     NSYIFFDEDDEYLEGMEDFELECKDVLMDVIETTSIDIYVQMIKRNITNY"
     gene            complement(10878..11666)
                     /locus_tag="KR294_002557"
     CDS             complement(10878..11666)
                     /locus_tag="KR294_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBH0240627.1"
                     /translation="MKVVIIPGHTLIGKGTGAVGYINESKETRILNDLIVKWLKIGGA
                     TVYTGRVDESSNHLADQCAIANKQETDLAVQIHFNSNATTSTPVGTETIYKTNNGKTY
                     AERVNTRLATVFKDRGAKSDVRGLYWLNHTIAPAILIEVCFVDSKADTDYYVNNKDKV
                     AKLIAEGILNKSISNSQGGGENKVYENVIVYTGDADKVAAQILHWQLKDSLIIEASSY
                     KQGLGKKVYVVGGEANKLVKGDVVINGADRYETVKLALQEIDKL"
     gene            complement(11805..12242)
                     /locus_tag="KR294_002558"
     CDS             complement(11805..12242)
                     /locus_tag="KR294_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HBH0240628.1"
                     /translation="MNKKLENRCSWQEYFMRLCETVAERGTCDRAYVGAIIVNSENRI
                     VSTGYNGSISGDKHCSEVGHEMRDGHCIRTIHAEQNALYYCAKEGISVKNCSIYVTHF
                     PCLNCTKAIIQAGIKHIYYRTGYRIDEYAIKLLQSSNVLYTKL"
     gene            13064..13573
                     /locus_tag="KR294_002559"
     CDS             13064..13573
                     /locus_tag="KR294_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH0240629.1"
                     /translation="MLSENIKTIRKSKGLSQQELAIKLNVVRQTISKWEQGLSVPDSD
                     MLISISEVLETPVSTLLGETIVESEVDNLKVISEKLEIINLQLAQRKNMRRKMFHWLF
                     ILLCAVILIVFVVLGRLNSPYLDWNYTDPETAVFGVAFHAFEWLFVRLVPIVLIGAII
                     GIFLTRKKI"
     gene            13987..14418
                     /locus_tag="KR294_002560"
                     /pseudo
     CDS             13987..14418
                     /locus_tag="KR294_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016295744.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            complement(14605..14798)
                     /locus_tag="KR294_002561"
                     /pseudo
     CDS             complement(14605..14798)
                     /locus_tag="KR294_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227347.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
     gene            14900..15406
                     /locus_tag="KR294_002562"
     CDS             14900..15406
                     /locus_tag="KR294_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBH0240630.1"
                     /translation="MKNEKKITVALLIVYLLILSWIILFKLQFSFSALDHIRQINLIP
                     FGGSVIANGKIDFDEIINNAIVFIPVGAYFSLLFKNKSVLKAIGSVLGISFVYEIIQF
                     IFAIGASDITDLISNTLGGIIGIALVYVLSIVLKDKTHKILNRIAIVCTVLVVAFLFM
                     LLAVNNIF"
     gene            15411..15687
                     /locus_tag="KR294_002563"
                     /pseudo
     CDS             15411..15687
                     /locus_tag="KR294_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436830.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4865 family protein"
     gene            15956..16528
                     /locus_tag="KR294_002564"
                     /pseudo
     CDS             15956..16528
                     /locus_tag="KR294_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902350.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
     gene            16631..17446
                     /locus_tag="KR294_002565"
     CDS             16631..17446
                     /locus_tag="KR294_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HBH0240631.1"
                     /translation="MFKIGEFSKLTQVSTRMLRYYDETGLLKPAKIDSLTGYRMYSAE
                     QISTLNRIIYLRDSGFNVAEIALALNFSNNAIIEQLDRKSIEIMDNIQKEQEKLKKIE
                     IAKKEVLHGKSELYFNITIKEIPSYCVLSLRKEIPNYYYEGELWKELSAFAKENKINI
                     SDETFSIYHNEEYKEKDVDVELCAIVNKIGKATGDFKFRFTEPVSMMACTMVYGDFSN
                     ISYAYRSFAKWLQENSQYKMKGSSRQIVHRGPWNEKNPENYLTEIQIPLENLL"
     gene            17527..18003
                     /locus_tag="KR294_002566"
     CDS             17527..18003
                     /locus_tag="KR294_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002608187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HBH0240632.1"
                     /translation="MTTYKVNSIGTICNNEKGAFIQLEAPYILALRALDGFSHINVLW
                     WFSDFDNTNFRSVLETEQPYKNAPEKMGIFATRSPVRPNPIALSAVEIIDIDYMSGLI
                     QIAYIDANDKTPILDIKPYTPSLDRVENPQVPDWCSHWPHSLEESASFAWESEFNF"
     gene            18017..18580
                     /locus_tag="KR294_002567"
     CDS             18017..18580
                     /locus_tag="KR294_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH0240633.1"
                     /translation="MSLQDYIFEKPVIETEHLILRTMNKNDIDDLKEWISDISLYEYW
                     GKRPSKSEKNPELLFDKSKKSTKSFHWGIVHKQDSKVIGEIWIYLIENNRMAKVAFRL
                     SKHYQGNGLMSEVLKNVIEFCFSKTELQKIWTDVHILNHASYKTLEKVGFQREGHIRG
                     GKMVNTYCDYYLYGILKSDYITRWCYG"
     gene            18835..19746
                     /locus_tag="KR294_002568"
     CDS             18835..19746
                     /locus_tag="KR294_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBH0240634.1"
                     /translation="MYAYENIEMSLNYIEQHLSEKIETEKLAEIACLSTFYYQRLFKR
                     LVKKSVQEYIKLRRLAMVIAELNNSEERILDIALKYGFSDHANFTRAFKEVYHITPDE
                     YRKNVPMLNTFDKPELSSRYIMIDENVPLIVGNIVLEIQRKTLRTKETYFGFEKTVNI
                     SEQIPAGESTGIDVPGQLWREFHAKKLQTENAIFNNDIELGVSHLASPDKGTFLYFAG
                     GMVSSTDVCPKNMVQHTLPAGEYIVCKIEAESFEELVTTALNQANKYLFETWLPNHNL
                     VTKPFMAEKYYKGNAEINYMEIWIIPV"
     gene            19824..20258
                     /locus_tag="KR294_002569"
     CDS             19824..20258
                     /locus_tag="KR294_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3788 domain-containing protein"
                     /protein_id="HBH0240635.1"
                     /translation="MINIKDINYVPNISEISVYIENSAFDELYQHMNNEYKAVCKIEY
                     SKDVWARGWNVKFKKSGKSLCVVYPKKNYFTVLVVVGNKEKEDVENLLPRLSEYVQEI
                     YRNTREGNGQRWLMIDLKSKNNVYQDVLRLIEIRYAIKCVKP"
     gene            20726..21375
                     /locus_tag="KR294_002570"
                     /pseudo
     CDS             20726..21375
                     /locus_tag="KR294_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009243519.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
BASE COUNT         7812 a         3009 c         3493 g         7061 t
ORIGIN      
        1 taagtttaaa ttttacgata ttttgtttga ttatttataa tataaaagca tactcttaat
       61 cttcaaaatt taaaaagagt aaaaaataac aaaaaaatca ctgacatttc actgacaaat
      121 tgtaattttg ttattataaa tacattgaaa atacttgatt attgaaaaat ggcataaaat
      181 aatacatttt atgccattta ctattatttg atagttttta acttatgaca taagatattt
      241 tttaacacat acaataaaat ataaaaaaat tgatattgca aataaaaaaa atacatatta
      301 gatgttatag aaaaaaagcg cacttatagg cttaaaatgt cacataaaag agttttaaag
      361 aataatatat tatgaacaca aattttgtaa tcacaaagga gtgataatat ggcaacagta
      421 tcaggacaaa tagtttttga tagaaataga agtgctacca ttgattctgg agactcagga
      481 atagccaata taccagttgt attacaagat atagcaactg gagttagact tgtggttctc
      541 acagatgcat caggaaatta tgtttttact aatgttccaa atggtaacta tagaattgta
      601 gaagcttttg gaactacagg aggagtacca acaccaggga attttgcaac agcgatagta
      661 ggtccagttc caattgcaga aatgccacct attagtcctc ctattggttc aacaaactta
      721 gatggtacaa cacctaacac actattaata acagtagcag gttcagatat aacaaatcaa
      781 aatatattaa atgggcctgt gatttataca cctatagaga atatattgga ttcttgcgta
      841 tctgtatcta atataaacct tattacagat gcagataacg gaacattcgg tttttttcca
      901 ccaggtacac caagtaatac aggacctgaa atagaacctt acccaaatgt gacgccagat
      961 tttacgtatg ttgtaccaga cccaactaag tttacacctt tagatggaga atatacagta
     1021 caaaatatta tgacaaatgc aatgagtaat gttataggag cttggtggcg tattgctgac
     1081 catactacag gaaatgaaac aggaagaatg atggtggtaa atggttttaa tcctggagct
     1141 gtatttttta aatcaacagt acaagttaca cctaacacta attatttatt tagcacttgg
     1201 attttaaacc tttttaaggt aacaggatat ccaccaccac agctaggtgt aagaatattt
     1261 gaccaaaata ataatatact atatcaagca acattaggag ctcaaattcc agttaataca
     1321 aacgcaccag aatggaaaga agtaggtact gtgattaatt ctcaaaataa taatcaactt
     1381 acagtagaat tttttagtga aggagaaagc gccattggaa atgattatgc tatagatgat
     1441 gtttctttaa gagaaatagc tgttccaact tttactccaa taaaaacaag taacacagaa
     1501 actgctaatg taggtgatat aatcacatat acagttacat tagataatac ttgtgatagc
     1561 cctttaacta atgtattttt tagggattta attccaaatg gtttagagtt tatacctgga
     1621 actgtaacgg ttgatggagt atctgtacca ggagtagacc ctaatacagg tttctcactt
     1681 ccagatattg gaggaggaac aggggttgaa gtaacttttg atgttgtggt tgaaagtatt
     1741 cctaacccaa atcctactaa taatatagct aatatagatt actcctatac acctgtagaa
     1801 ggcggtatac caaatgattt ttcagtagat tctaatccag ttcctgttga agtaatatca
     1861 gcagatattg aagttacaaa attatctgaa cctactatag tgaatccagg agaggaatta
     1921 atatacacta taaaagtagt aaataatgga ccattcccat ctgaaaatgt ggttttaaca
     1981 gatgatgtac cagcttctat tataaatcca gagtattcat tagatggagg agtaactttt
     2041 caaccatgga ctggaagttt aaatataggg acattagaag taggagagac aagagttatt
     2101 ataattaggg gtattgtaaa tccatcaaca gtaggaatta taacaaatac agctgtagta
     2161 tcttcaacta cagcagaccc aaaccttaat aataatacat ctacaataga gacagaagtg
     2221 aatttattag cagatatttt agtaatgaaa acagcagaac ctaattcagc tgttccaggt
     2281 actttattga gatatactat tcaagtagaa aacttaggac cagcaaatgc tgaaaatgta
     2341 atattaaatg atgatattcc agcttctatt ataaatccag aatattcatt ggatggagga
     2401 gcaagttttc aaccatggaa tggaagtctt aatataggaa ctttaaactc tggaatttca
     2461 ttaacagttt taattcaagg aacagttagt ttaaattctt cagaatatat agtaaataca
     2521 gcaacagttt cttcaactac acctgaccca gatttaagca acaatatatc taccattatt
     2581 acaccagtta acccacaagc aggtatttct attataaaag tagctgacga ggatgtagct
     2641 gttccaggag aagaatttgt atatacaatt gaaattttta atgaaggacc atctaatgct
     2701 acgaatgtag ttttaacaga tgatatacca gatgttattt taaatccaga atattcattg
     2761 gatggaggag caactttcca accatggaat ggaagtctta atataggtac agttgcacca
     2821 gggcaattaa taagaattat cataaaggga ttagtaagtt caactgctac aggagatatt
     2881 actaatacag cagaagtaag tgcagatgta ccagaaccag ttacggattc atcaacagtg
     2941 acaactccta tagttccatc agcagatata gaagtaataa aaactagcaa tatggataca
     3001 gcagttccag aagaaacttt cagttatact ataacagtta caaatttagg accatctgct
     3061 gcacaaagta tcgttttgac agatgatata ccagatgtta ttttaaatcc agagtattca
     3121 ttggatggag gagtaacttt ccaaccatgg aatggaaatc ttagtatagg cactttggat
     3181 gctggagaaa taagaagtat tataataaga ggaacagtga gccagacagc agtaggtaca
     3241 attataaata cagcaacaat aagttcacct acacctgacc caaatccaga taataatact
     3301 tcaacagatg aaacagatat aagtccatta gcagatattt ctgtgataaa aggcaacgaa
     3361 ccagttgcta taccaggagg aagatttatt tatggaattg aaattgcaaa tgcaggacca
     3421 tcttttgcag agaacgtaac tttaacagat aatataccag cttctatttt aaatccagag
     3481 tactcaatag ataatggagt gactttccaa ccatggaatg gaagccttaa tataggtact
     3541 ttagatgctg gagagataag aaatatcata ataaggggaa cagtaagtca aacagcaata
     3601 ggtacaatta taaatacagc aacagtaagt tcaactacac ctgacccaaa tctaaataac
     3661 aatacttcaa catcagaagc agaggtaagt tcatcagcag atatttctgt agtaaaacga
     3721 agcaatcaga ctgttgttgt accaggagat gtactagact atacaattga ggtgagaaat
     3781 gcaggaccgt ctactgctca gaacgtaact ttaacagata atataccagc ttctatttta
     3841 agtccagaat attcaataga taatggagtg acttttcaac catggaatgg aagtcttagt
     3901 ataggcactt tagatgctgg agagataaga aatatcataa taaggggaat agtaagtcaa
     3961 acagcaatag gtacaattat aaatacagca acagtaagtt caactacacc tgacccaaat
     4021 ccagataata atacttcaac atcagaaata gatataagtt catcagcaga tatttctgta
     4081 ataaaattag caaataaaac agaagcatgt gtaggagagc aaatagattt tgtaatagta
     4141 gtatcaaatg caggaccaga aaatgctcaa aatgttactt taatagacaa tgtttcagat
     4201 aagcttaaga aagcagtatt ttcacttgat agaggtgtaa gtttccaacc atggactgga
     4261 agtcttaata taggtacact accagctgga actttaagag tgattatatt aagaggaatt
     4321 ataaaatcaa catgtcttga tagattaaca aatattgcag aagttacttc aacaacacca
     4381 gattcaaacc ttaacaataa tatatcaaga gtgcaagtag aaataaaaca attttgttgt
     4441 aatgattgtg gttgtaaaga ttgttgctgt aattgttgtt gcaatgattg tggttgtaaa
     4501 aattgttgct gtaattgttg taaaaatgac ttttggtgtt gattttataa aataattttg
     4561 tataccttaa attaaactga aataaaaaat aaattcacat atgagtaaaa tattttataa
     4621 atattaataa attttctatc tttgatatgg accacattcg taatactagt tattaaatga
     4681 agtggtcctt tttaattcat taaaattatt tattctaatt aaattttaaa tgtattaaat
     4741 aattttaatt ttttataaaa aatattcata tgttatttat attaaagttt agatatctaa
     4801 aaatactttt agaatttatt atattatgtt aattttttat atcttataag gattgtattt
     4861 ttctaactat aaaaatagta ttatacttat atttaaaaat aaaagaattt tattcctatt
     4921 gtgtaaagtg agaatactat tttcttatat tggtataata atagtaaatc tataatatag
     4981 aaaagaggta tttctagtat gcatgaaaat aaaaaaaatc tattagacgg aagcttagct
     5041 caatataatg atacagcagt tccaaaaata ccagtatttg ctggtaacga tataacttca
     5101 gaagtttatt attttaaacc taatcaagtt cttaatgctc atagacaccc taatggtgaa
     5161 caaatatttg tgttcctaaa aggagaaggt aaaatgaaac ttggtgagca tgaatgtgat
     5221 gtaaaaaacg gagatactgt atttgtacca acaggagagt ggcatgaaat tactaatgga
     5281 agcaatgaag aaatggtagc cgttcaaatt acaaaaatta atgctggagc agaatacaga
     5341 ggatagatat ataagtacag ttagtacttt aatatctatt ttattatata aactttaatc
     5401 tcaaatataa aaagagtctt ttaaaaggct ctttttatat ttttgttaat tttcattata
     5461 aaaacaagaa aatatctagc taaaactaat atattttatt taatattttt tatagcattg
     5521 tttgcaaact cagtatttac gatatcttta taaggtgctt ccttatctag ttctttagct
     5581 tctttcataa cagtcatcaa tttcttcaaa ccttcctctt ttaatacagg attttgagac
     5641 catgcatcta ttgatttata tctatctaca actgttgtta aatcttctaa agatatatct
     5701 tcaaagaaag gttgcatagc cttagctact tctttgctag atgcttgttg aatccataat
     5761 tgacctttat aaacagcatt tgtaaatctt tgaattaaat ctttattgtt tttcatgtat
     5821 gatctcgtag tagagtatgc tgtaaaaggt atttctccag aatcttttcc tatagatgta
     5881 actatatatc cactaccttc tttttccatt gctgttgctg taggttcaaa tgctgttgta
     5941 aagtcaccct ctccacctgc aaaagctcca gccattacac caaattgtac atcagttctt
     6001 acattaacat tgcctgcttt tagattttct ccaatagtaa gacctttttc ttttagaaca
     6061 tattcaaaag tcattagtgg aactccacct tttctaccac ctaatatttc ggttcctttt
     6121 aaatcattgt aagagaaatt aggcattttt ttcctagcaa ctagaaaact accatctctt
     6181 tttgtcaatt gagcaaagtt cactgcataa tcgtttttgt tttgattata tacatatata
     6241 gatgcttcag gacccattaa acctacgttt gcttcacctg aaatcaaagc tgccatagtt
     6301 ttatctgcac cttgggtatt tataaggtca atctttatac cttcatcttc aaagaatcct
     6361 ttcgtaatag cagcatactg tggagcataa aaaacagagt gagtaacttc tgctatagtt
     6421 actttatcca gatttttaga cgaagaagat tcatcttttt tgtcattaga gttaaaatca
     6481 catccagtta gacatattgt acttacaatg atagagcttg ctattgcgac tattttttta
     6541 aacataataa atacctccca taagacatac gaatagtata tagtattaaa tatttattgt
     6601 agttgttaca aaaatgtatc tatacttata atatttctac aaaaacttaa taataatttt
     6661 cagttttatg tttagttttt tcagtaatgt gtaatattgg ataaattata ttgattattt
     6721 ataaactaag taataaaatt aaaataatat cacttttttg tctattatat ataaggaaaa
     6781 attttttaat aatataaatc atattcattt atattattaa aaaatttgtt tatagaaact
     6841 tttattattt tatataaaag tgataaaaac ttatattttg tatttaatag agtgttgcta
     6901 agtgaatata tttaaaatgg aggaaacttt atgaaacaaa ataaatatga tgatgataga
     6961 ttttttaata aatacagtaa aatggaacgt tctacaaatg gattagcagg tgctggagag
     7021 tggcatgttt taaaaaaaat gttacctgat ttcaaaggaa aaagagtttt agatttagga
     7081 tgtggatttg gatggcattg tcaatatgca gttgagaatg gagcaatttc tgctgttgga
     7141 gttgatattt cagaaaaaat gttaaaagaa gctagaaaca aaacgcaact tgataatata
     7201 aattacatat gtatgcctat tgaagatatt aattttccaa aagatagttt tgatgtagtt
     7261 attagttcct tggcatttca ttatattcaa tcatttgaag atatatgtaa gaatataagt
     7321 aattgtcttt caaataaagg taattttgta ttttctgttg aacatcctat atttactgca
     7381 tatggaagtc aagagtggta ctgtgataaa gatggaaata atctacactg gccagtagat
     7441 agatattttg aagaaggagt acgtaggtca aattttctag gagaagaggt tataaaatat
     7501 cataaaacat taacaactta tttaaatgcg ttaatgaaaa caggatttga aatattagaa
     7561 attattgaac ctcaaccaga agaaaaactg ttagatacaa ttcctgatat gaaagatgag
     7621 ctacgtagac ctatgatgtt acttgtatct gcaaaaaaaa gataagtaaa tataaataat
     7681 cattattgta gaaaaaaagt tgtagaaaat aattacacta atggagatga ttataccagt
     7741 ggtattaatt acaccagtag taaggaggca aaagcattcg ttgcttttgc cattttttaa
     7801 gttgcaatta tacttctacg tagtatattt cgtttccatt ttcttctata agctttttca
     7861 tatcttcaaa ttttaaaaat acagtagcag tattatcatt tggatgtata cctattttat
     7921 ccatttttaa taaatcctta tcaaatacaa cttttacaac agcctcttta tcatttaata
     7981 taccaaaagg agtcacagct cctttagtaa gtttcaagta tttttgaagt ctttcttctg
     8041 atgcaaaact aagaggttta ctatcaattt gttgacgaat atcttttaaa tctgcttttt
     8101 tgtctttacc taatacaact aaaaaatgtt cttttccttt agcatcacga agaaataggt
     8161 tttttacaac aaattccata tgtaatgttt ttaattcttc catttcttca attgtataaa
     8221 ctggtggatg atttacagcc tcataaggta tgcttaactc atctaatttt ttatatactt
     8281 cctgttgttg attgttcatg atttcctccc attagaaatt tattttatat ataaataata
     8341 ttatcacaga aaactttaaa agaaaacgtt ttatataata tagacaatag attatatttt
     8401 tataaagaag caagaatact caataaaact taaagaaatt aaacgatttc taaaaatacc
     8461 ttgaaaatag aaccttattt gccatttata aattatataa aaagggatta tataaagtca
     8521 tatatgaaaa aactatatta tactatcttt tctttttgga ataaactata ctttaaatat
     8581 agatatttaa tttaaataaa ttttacagta ttaatagtaa attatcttag aaaggaatgt
     8641 gctttatatg tctacagaca aagttgttgg aatcatagat gaagaaacgg cagaacttgc
     8701 aggaattgaa tatactggta aaatttatgc ttcttctggt gttataaaac atataaagaa
     8761 aaaacataga tgtcaactga gtaaggatat ttttaatgat ataatagaca ctataaaaat
     8821 ggtattaaag tcacctgaat atataggaag tcatcctaaa aaacctggaa aaagtgtgga
     8881 gtttataaaa aaaattgatg attatatttt agtagctaca gaattagata caaaaaaagg
     8941 atatttatat gtatcttcaa tgtatgctat aaaagaagca aaattagaaa gtagagtaaa
     9001 cagtggaaga gtaaaacaat atgatggtta acataatatt attaattttc cctaaaatat
     9061 tgaaaaatat tattatataa gttataatat taatatacac gtagatattt attagttaga
     9121 tttgaggttg gaaaaggcac ccaatacgct actatagagt agttaataga gatgcaggat
     9181 acgccgccct gccaaatcta attaaattaa aaagagagga ttaattcctc tcttattgtt
     9241 tttttgagat actaatttaa tctataatag aaagattgaa ggtcgtttat acaaaaaaat
     9301 tttcagttat atacattaaa ctaattaaat aagatattta taatctatat gtgatacata
     9361 ttatatatta ataaaagaaa aatatataga aaatccttat aaaaatttaa attgtaatga
     9421 ataggaagta attaaaaaga atttttattg atttttaaaa atttagttag aaactatatc
     9481 attatggtaa aaaatgtatt ataatgttta gaaatattat aataaggagc gattaaacat
     9541 gaatctatcg aagaaaatag aagataaaag aaaagctaaa cagagagctg aaaaagttaa
     9601 gaaagctaaa attgctacag ctggtgtggt attaggagct gttactggtg cagtgagtgg
     9661 agtacttttg gctcctaaat ctggaaaaga aacaagagag gatataaaag atgcttcaca
     9721 acaaattgct gaaaagataa atatgaaaac tgtagatgta aaaggcaaag tatctgagaa
     9781 gctagaggat aaaaaaggaa actttataga atcaaagaaa aaaataaaaa aatatataga
     9841 taacaaaaag agtgttgaaa attctagtga ggaagataaa ataatagata tagttgaacc
     9901 agttagtgtt actgaggaat aatatggaca atacaataac gattaacata agtataatat
     9961 atgtattatt agctatactt gcttgtattg ctttagttta tttaattatt gtacttgtta
    10021 aactacataa gattttaaat aatgttggaa ctatgttaaa tgaaaatact caaaatataa
    10081 atacaacttt aaataatctt cctaatgttg tagaaacttt tggagaagta ggagaaaata
    10141 tgaaagatgt aacagaagta gttactgaag ttacagcaga ttttcttgtt actaaagaca
    10201 gtgtcaaatc aaatatggat gttatagttg atatattgac tataattaaa aacatttttg
    10261 tagataaaaa ataataagtt aatataaaat aagcctataa gatataattt aaacgacctt
    10321 aaaatagcat ttataaggtc gttttttatt agcttgattt gacactatgt gtttttaata
    10381 attggtaata ttcctcttta tcatttgaac atatatatct atgcttgttg tttcaattac
    10441 atccataaga acatctttac attcaagctc aaaatcttcc attccttcta aatattcatc
    10501 atcttcatca aaaaagatat aagaattata tagccattct tcaaattttt cttcaagtat
    10561 atcccaatac gaactccaaa ataatccaca acctgatata taagatgctc tactttgatt
    10621 tatataaact tcatttagaa gcttttgtaa tctactgcta taaagaaaat ctgctcttcc
    10681 actgcttgat attaattcat ttaaatcttc tattgacatt aattcaactt taccactttt
    10741 atcataagga gtataatttt catcaaccca tttatgtggt ttgttttctc tgcatactgt
    10801 tgctatcaac tctacaactt ttgttcttat cattttttta tcctaactta tttatttttt
    10861 ataaaataat catgatttta taatttatct atttcttgta atgctaattt aacagtttca
    10921 tatctatcag caccatttat tactacatca ccttttacaa gtttattagc ttctccacct
    10981 acaacataaa cctttttacc taaaccttgc ttataactag acgcttcaat tattaaagaa
    11041 tctttcaatt gccaatgtaa aatctgagca gccactttat cagcatcacc tgtataaacg
    11101 attacatttt catacacttt attttcccct cccccttgag aatttgatat agatttgttt
    11161 agtatacctt ctgctatcaa tttagcaact ttatctttat tattaacata ataatctgta
    11221 tctgctttac tatctacaaa acatacttct attaatattg ctggtgcaat agtatgatta
    11281 agccaataaa gacctctaac atcagacttt gcacccctat ctttgaatac tgtagctaac
    11341 ctagtattca ctctttctgc ataggttttg ccattattag tcttatatat tgtttctgtc
    11401 cctactggag ttgaagttgt agcatttgaa ttaaaatgaa tctgaacagc caaatcagtt
    11461 tcctgtttat ttgctatagc acattggtct gctaaatgat tacttgattc atcaactctt
    11521 cctgtataaa cagtagctcc acctatttta agccatttaa caattaagtc attcagtatt
    11581 cttgtttctt tgctttcgtt tatataccca acagctcctg taccttttcc aattaaagtg
    11641 tgccctggta ttattactac tttcaaacta acatctcctt tacaattaaa tttaacttct
    11701 atttaatata tgcataacct agaattttgt ttctttttat atcttatact tttattataa
    11761 cccattttgt aaaaatatag aatattaagt aaataatgtt aaaattataa ttttgtatat
    11821 aagacattac ttgattgcaa taattttata gcatattcat ctattctata tccagttcta
    11881 taatatatat gtttaattcc agcttgaatt atagccttag tacaatttaa gcatggaaag
    11941 tgagttacat aaatagagca atttttaact gaaatacctt cttttgcaca ataataaagg
    12001 gcattttgtt cagcgtgaat ggttctaata caatgtccat ctctcatttc atgaccaact
    12061 tcactacaat gcttatctcc agaaatacta ccattatatc cagtagacac tattctgttt
    12121 tctgaattga caattatagc tcctacataa gctctatcac aagttcctct ttcagctact
    12181 gtttcgcaca gtctcataaa atattcttgc catgagcatc tattttcaag ttttttattc
    12241 aaatcatata cctccaaaat ttatatctaa tatataagat ttatacctta aaaataatat
    12301 taaaaacaaa tttatatgat aaataaaatt tattaatact gtttttagtc taaattattt
    12361 cattttaaat taaagttaca aggaatctaa gattatatat atctttcttc gtaatatgaa
    12421 tgttacaata taaaaaactg tctcaataaa atagagacag ttttacagtc aaagtttata
    12481 atacaagttc atatttttct ttaaattctt ttacagcttc gggccatgcc ttttgttctg
    12541 taataccttt ttctttagct attttaattg caatctctct tatcattgca gcgccttcta
    12601 atattcccat ttttaatctc ccttcaaata tctttttgta tagaatataa atagtgctaa
    12661 gatttattac atgctgcata tacaatatct atacaacaca taacttgtaa attcctttta
    12721 ttttcatacg tctttaaccg acatataatt atattcaata agttttaaaa ttatgaactc
    12781 aattataatt atttttattt ttttagaatc taaacactaa aaattgtagg taaatttgtc
    12841 ttatgccttt ataaatattt ctacagtttt aattactgga catatctatt tttattataa
    12901 aaagcgatta aaaatggaga atatcctcat aaaaactata tataagcaaa acggttaaag
    12961 gaaaaagaag aaatttactt gaatgttaaa atgcgttgct tgaagcaatg ggcagttttg
    13021 cctataatat cggtaacaac tgaaagaaag gtggttagcc ctaatgttaa gcgaaaacat
    13081 taaaacaatc aggaagtcaa aaggactttc acaacaagaa cttgctataa aactgaatgt
    13141 agtgcgacaa acaatatcta aatgggaaca aggactgtcg gttcccgatt ctgatatgtt
    13201 gatttccata tcagaggtgc ttgaaacgcc cgtaagcact ttacttggag aaactattgt
    13261 tgagtcggaa gttgataact taaaagtgat ttctgaaaaa ttagagatta taaacttgca
    13321 acttgcacaa agaaaaaaca tgagaagaaa aatgtttcat tggttattta ttttattatg
    13381 tgcagtcata ttaatagttt ttgtggtctt agggagacta aatagtcctt acttggattg
    13441 gaattatacc gaccctgaaa ccgctgtttt tggagtagct tttcatgctt ttgagtggct
    13501 atttgtcaga ttagtaccga ttgtccttat aggagcaatt attggaatct ttttgacacg
    13561 taagaaaata tgaagtaact ctgcttttta taatacagca agcgttcctt aaaagcgtca
    13621 ttctacatgg caatcgagga cgactatgta aggaagaacc tttttgattt ccaactaagc
    13681 gaagttattg aggacgacag taggcccaaa accgcattaa gtaaagtaca ggaagcaaga
    13741 ctgctggact tatactctca tgcgtcagat gcaggaaatg cgaggtctgg tagcatgatt
    13801 tacaacgatt tgtacaacga ctacgagtag aaatatatgg agataagtat tatctacgaa
    13861 atcagaaaag aaatgacttg ataatttact catgttataa ttattgatgt gaaattaata
    13921 aatcgaaatt ccttttttgg atttaacaat actgagtaag gaaaaagtga attacttttg
    13981 caaggaggtg ttatttggat ggtgctagca ggtattttga ttgtagtaca aggctttttg
    14041 actggtcctt tagcaaaaaa aattggtgag aagcgactaa tactgatagg tatgttttgc
    14101 aaagccttag tagcgtttgc catggtattg acaactgggt ttgttagtgt gttggtggtt
    14161 tttggcttat ttgcggtatc ttctgctatt acagtaccca cattaaacgc aaccctttca
    14221 aaaactgaca atcagcataa aggaacactg atgggatttg ccagtaccgc cggaaatctt
    14281 agcaaagtta ttgctccttt attaactggg tatctgtatg aaagcaatat tgaattacca
    14341 tatataacca cgggagggat agccttaatc ggagtggtta tctgctatat ctggataaaa
    14401 aatcaaaaga acaaatgatg gaagaggacg tttatatgga ggttatacac agtaactaat
    14461 ctggtataga aattcaattg aggcttttct gctttattaa agtcttgcta ctacttaacc
    14521 ctataatatc cttaattcat tatgacaaat tccaattcaa cagttttgat acacataagg
    14581 aggtaacaat actatggaaa attatcaatg aagtgctaat tctttatcag tgaagttatc
    14641 cataagtttt tctacctgta atcgtctggt gctttttgcc agatcattgg taggtaagaa
    14701 aaattcatca acagacacat gaagtaatga tacaaggtca cttgtatgct tggatgttgc
    14761 cctttatttt caatattagt taagtaacgt gggtcaatat ttgtaattcg attttaggga
    14821 aatatttaaa gaaatatttt cgttttattt ctttaaatct tcaagaatat tgatagtttt
    14881 ttgaaagtag gtgtgtatta tgaagaatga gaaaaaaatt acagtcgcat tgctcattgt
    14941 ttatttattg attttatcat ggattatttt atttaagcta caattttcat tttctgcgtt
    15001 agaccacata agacaaataa acttaattcc ttttggtggt tcagttattg caaatggaaa
    15061 aattgacttc gatgaaatta taaacaatgc cattgttttt atccctgtag gtgcatattt
    15121 cagtttgctt tttaaaaata aatctgttct aaaagcaata ggttctgttt taggaattag
    15181 ctttgtatat gagataattc aatttatatt tgctatcgga gcaagtgata ttacagactt
    15241 aattagcaac acattagggg gtataattgg aattgcatta gtatatgtat tatctattgt
    15301 tctaaaggat aaaacacata agatattaaa tcgaatagca atagtatgta ctgtattagt
    15361 agttgccttc ttatttatgc ttcttgctgt aaataatata ttttaatgcc atgttaatta
    15421 catgttgttt tggaaaagac tttaatctgt caaagtttgc ttttgaaatt gaacatgaaa
    15481 ttacaccaat ggaacaaatg aaagctataa atttttcatt ggagaaagat gactgtacaa
    15541 gtaaagtatt aatatacaat ccagacaaat ggaaatatgt agaatactat ttctataaag
    15601 atagacctat taaaaaaact attggaaaaa tttattcaat tttgcatttg tcacaataaa
    15661 atatgttttg aaatattgaa tacttaaata tgcaaaaaaa caaatgtaac tggctatggg
    15721 gctatatcta ctaaaaagct atgtgatagg ttgggattaa atttaaacat cacttctaga
    15781 aggcatgaat acacaaggct gacaaactat acagttatga ttaaacgata ccaacgggat
    15841 tgaaaatttc gtgaagaact ttgagaagtc ctattacaca tgagcaacag caacgaagct
    15901 attgaagcaa ggacgcaggc aatctagcgg ttatctgaca aaggagttgt aggacttgaa
    15961 tgtagatact atcagaacgg atataccgac cagctctgcg gttacagatg tgattgtgta
    16021 gaatatcgag cagtcgggaa cggacacttt atctgctacc tacgaagtag atcagcagat
    16081 aaaagagaga gaacagacaa cagcggtcaa ggcaacctat accgtaaaag tccatgtgga
    16141 cgctgacggg gatatggtaa tcgttcagaa ccttactctt gcaccagcaa tcgaaaaatc
    16201 agactatgag ccaaagatat cagaaacaga cgcaagcgtg gacgctgata ccgttaatga
    16261 cgctaccgca tttctggaaa cattctttga ggtgtacccg acagccacag aaaaagaact
    16321 tgcctattat gtatcggaaa atgtgattga acctatcggc agggactacc tttattctga
    16381 attggtaaac ccagtcttta caaaggacgg ggacaatgtg aaagtcaagg tagctgtgaa
    16441 attccttgat aatcagacaa aggcaacgca ggtgtcgcag tatgatcttg tactccaaaa
    16501 ggatagcaac tggaagattt taggataaca tggaaatggg cttgtatcat aattatagtg
    16561 tgcaagccct tttcatattg aagtatcaat aatcaataat tataattagg tacatgaatg
    16621 gagggataaa atgttcaaaa ttggtgagtt ttcaaaattg acacaagttt ctactcgtat
    16681 gttgcgttat tatgatgaaa cgggtttatt aaaacctgct aaaattgatt cattaactgg
    16741 atatcgtatg tattcagcag aacaaatctc aactttaaat agaattatat atttacgtga
    16801 tagtggcttc aatgtcgctg aaattgcatt agccctcaat ttcagtaata atgccattat
    16861 agaacagctt gatagaaagt ctattgaaat tatggataat atacaaaaag aacaagaaaa
    16921 actaaagaaa attgagattg ctaaaaaaga agtgttacat ggcaaaagtg aattgtattt
    16981 taacataacc attaaagaga taccgagtta ttgcgtttta tctttaagaa aagaaatacc
    17041 aaattattat tatgagggcg aactctggaa agaactctct gcttttgcta aagaaaataa
    17101 aataaatatt tctgatgaaa cattctcaat atatcacaat gaagaatata aagaaaaaga
    17161 tgttgatgta gaattatgtg ccattgtaaa taaaatagga aaagctacag gagattttaa
    17221 gtttcgtttt accgaaccag tttctatgat ggcttgtact atggtatatg gagatttttc
    17281 taatatttct tatgcttatc gttcatttgc aaaatggctt caagaaaaca gtcaatataa
    17341 gatgaaaggt tcaagccgtc aaatagttca tcgtggaccg tggaacgaga aaaatccaga
    17401 gaactatcta acagaaatcc aaattccttt agaaaatctc ttgtaaaaaa tgataatctg
    17461 ccttgacttt aacatggtgt taaggtttat cgtttattta tcaagaagaa aacggaggaa
    17521 aatataatga caacttataa agtaaattca ataggtacta tctgcaacaa tgaaaaaggt
    17581 gctttcattc aactagaagc accatatatt ctagcattaa gggcattaga cggattcagt
    17641 catataaatg ttttatggtg gttcagtgat tttgataata cgaattttag aagtgtattg
    17701 gaaacagaac agccttataa aaatgctcca gagaaaatgg ggatttttgc aacaaggtcg
    17761 ccagtacgcc caaatccgat tgctttatca gcagtagaaa ttatcgatat tgattatatg
    17821 agtgggctga tacaaattgc ttatattgac gctaatgaca aaacgcctat cttggatatt
    17881 aaaccataca cgccgagttt ggatagagtg gaaaatccgc aagttccaga ttggtgtagt
    17941 cattggcctc acagcttaga agaatctgct tcttttgcat gggaaagcga attcaatttt
    18001 taaggagtga tgaaccatga gtttgcagga ctacattttt gaaaaaccag taattgaaac
    18061 agaacatctt attttaagaa caatgaataa aaatgacata gatgatttga aagaatggat
    18121 tagtgatatt tctttatacg agtattgggg gaaacgtccc tcaaaaagcg aaaaaaatcc
    18181 agaattactc tttgataagt caaaaaaatc tactaaaagt tttcattggg gtattgtcca
    18241 taaacaagat agcaaagtga ttggtgaaat atggatatat cttattgaaa ataatagaat
    18301 ggcaaaagtg gctttcagac tttctaagca ttatcaaggt aatggactaa tgagtgaagt
    18361 gttgaaaaac gtaattgaat tttgtttttc aaaaacagaa ttacaaaaaa tatggacaga
    18421 tgtgcatatt ttaaatcatg cttcttacaa gacattggag aaagtcggtt ttcaaaggga
    18481 aggacatatt cgagggggga aaatggtaaa tacctattgc gactactacc tatatggaat
    18541 tttaaaatct gattatatca ctaggtggtg ctatggctaa tattgaagcg acgattggcg
    18601 aagcaatgaa caatacagtt ccaaaggtct atgatacgaa aagcattaaa agatatgtga
    18661 tgaatttatt agatatggct cattaaaaag taccaaagaa ataaaagtta ccatatagac
    18721 aaaattggtt ttttatatct tttgatttct tataagataa tggcattgtg cgacaagcta
    18781 tgcaaaaaat tttcatgtat actttgatta taatttatac aaggaggtac tgatatgtac
    18841 gcatatgaaa atattgaaat gtcattaaac tatattgaac aacatttaag tgagaaaatc
    18901 gaaacagaga aactggcgga aattgcctgt ctttctacat tttattacca acgcttgttt
    18961 aaaaggttag ttaagaaatc agttcaagag tatatcaaac ttcgccgttt agcaatggta
    19021 atagcagaat tgaataattc agaggaaaga atattagaca tagctttaaa atatggattt
    19081 tcagaccatg ctaacttcac aagagcattt aaagaagttt accatattac tcccgatgaa
    19141 tacagaaaga atgttcctat gttaaataca tttgacaagc cagaactttc ttcacgttat
    19201 atcatgattg atgaaaatgt cccattgatt gtaggaaata ttgttttgga aattcaaaga
    19261 aaaacattaa gaacaaagga aacatatttt ggttttgaaa aaacagtaaa tatttctgaa
    19321 caaattcctg ctggagaaag tacaggaatt gatgttccag gtcagctatg gcgcgaattc
    19381 catgcaaaga aactgcaaac cgaaaatgcc atttttaaca atgatattga acttggtgta
    19441 tctcacttag caagtccaga taaaggaaca ttcctttact ttgcaggagg tatggtttca
    19501 tcaacagatg tatgtcctaa aaatatggta caacatacat taccagcagg tgagtatatt
    19561 gtatgcaaaa ttgaggcaga atcttttgaa gaacttgtta ctactgcttt aaatcaagca
    19621 aataagtatc tgtttgaaac ttggcttcca aatcataatt tggttacaaa gccattcatg
    19681 gcagaaaaat attacaaagg aaatgcagag attaattata tggaaatatg gataattcct
    19741 gtgtaaacag taaatgctaa ataggaatta tctgacgtaa taaaaaggaa atagaaagct
    19801 tataaaggag ggcatagtcc gttgtgataa acataaaaga tataaattat gtacctaata
    19861 ttagtgaaat aagcgtttat attgaaaact ctgcatttga tgagttgtat cagcatatga
    19921 acaatgaata taaagcagtt tgcaaaatcg aatacagtaa agatgtctgg gcacgaggtt
    19981 ggaacgtaaa gtttaaaaaa tctgggaaat cattgtgtgt tgtctatccg aagaagaact
    20041 actttactgt attggtggtt gtaggtaata aagagaaaga agatgttgaa aacttgttac
    20101 ctaggctttc tgaatatgta caggaaattt atcgtaacac tagagaggga aatggacaaa
    20161 ggtggcttat gatagactta aaatctaaaa ataatgtata tcaagatgta ttaaggctta
    20221 ttgaaattcg ttatgccata aaatgtgtaa aaccgtaata aaaatatttt tcacatacgt
    20281 aatctcaagg tattatcgtt gagacaagta acctatataa ttatgggaaa tgagattttt
    20341 agatacttaa gaaagtactt tagggggctt gcgttatgga aagatttaag tacaattcca
    20401 cacaatcaaa tacaatctaa taaaacttta ctaaaaattg aatgcaatac agctttaaag
    20461 gctcgtacaa actatatgtt ttgtgcgggc ttttttcatt taataggaat ttggattcgt
    20521 cagagagtat attataaaaa taaaacgata agggtacctt aaaaataagg tacctcaggc
    20581 tgtagacaaa gtcccggact ctcgtctggg cttttcttat atttgagtta tccacaattc
    20641 aactttttaa gagttatctt attaagaaaa aagtgtatgt tttccaccct atagttttac
    20701 ttctgtgata tttgcagatg ccactcaagt agaaagtggt ggtacggcag aagatgtcat
    20761 gcagagttca gaaagtctgg gactaccgcc taattcctta gacacggaaa gctcaatcaa
    20821 gcaggggtgt aagtattttg cgtccctgct ttcttcctgc aaaaatcaag gtatcgacga
    20881 tttgaatgta gcgatacaat cttacaacta tggcgggggt tatgtgggct atgtggcagg
    20941 aaaagggaaa aagcacactt ttaatcttgc agagagcttc gcccgtgaga aatcgggtgg
    21001 aaagaaagta acctacgcca acccgatagc cgttgcaaag aacgggggct ggcggtatgg
    21061 ctatggaaat atgttttatg tggaattagt caatcagtat ttaactgttc cgcaggtgtc
    21121 gggggaactg gcacaaaagg taatgaatga agcgttgaag tatcaagggt ggaaatatgt
    21181 gtttggggga agcaatccca acacttcctt tgattgtagc ggacttgtgc aatggtgcta
    21241 tggaaaagct ggtatctact taccgagaac ggcacaaaca cagtatgacg caacccagca
    21301 tatcccttta tcgcaggcaa aagctgggga gttgttcttt ttccattcaa cctataacgc
    21361 tggttcgtat gtaac
//
LOCUS       DAEPKC010000069        21085 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.069, whole genome shotgun sequence.
ACCESSION   DAEPKC010000069 DAEPKC010000000
VERSION     DAEPKC010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21085)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21085)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21085
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.069"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(183..1574)
                     /locus_tag="KR294_002571"
     CDS             complement(183..1574)
                     /locus_tag="KR294_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HBH0240636.1"
                     /translation="MYKLIDKKDIDFLIDTCGEENVLVGSDINEDFSHDELGGIEKYP
                     EVLVNVLETEQVSKIMKYAYKNNIPVTPRGQGTGLVGAAVAINGGIMINLCKMNKILE
                     VDYENLTLTVEPGVLLMTIGQYVQDRDLFYPPDPGEKSATIAGNINTNAGGMRAVKYG
                     VTRDYVRGLEVVLPNGEIINVGGKVVKNSSGYSIKDLLVGSEGTLGIVTKAILKLLPL
                     PKKSISLLIPFPDLSMAIETVPKIIKSKSIPTAIEFMERDVILAAEEFLGKKFPDNTS
                     DAYLLLTFDGNSTEDIEKEYEKVANLCLENGALDVFISDTQERNDSIWSARGAFLEAI
                     KASTTQMDECDVVVPRDKIAEFIRYTHELQDKLKIRIKSFGHAGDGNLHIYILKDGMD
                     DNTWKIRLKETFDYMYKKSRELSGQVSGEHGIGYAKKEYLHESNSDAYMMLIKNIKLA
                     FDPKNILNPGKIY"
     gene            complement(1585..2805)
                     /locus_tag="KR294_002572"
     CDS             complement(1585..2805)
                     /locus_tag="KR294_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding protein"
                     /protein_id="HBH0240637.1"
                     /translation="MSKIVVNQDKITDLKRILEICPFGAIEEKSGIVEISAGCKMCKL
                     CVKSGPKGAFEFIESSKVQINKDEWRGIAVYVEHHNGNIHPVTYELIGKAREMASKIK
                     QPVYCVFVGKDIKDKCSNLISYGVDEVFVYDEDEFKDFRIEPYSKAIENFIDKIKPTI
                     VLVGGTTLGRSLAPRLAARFRTGLTADCTILDIQSNTDLDQIRPAFGGNIMAHINTPN
                     NRPQFATVRYKIFSAPEKIENTTGKITLCKVEKKELKSKIKVLSVKEKNKEVGLEEAE
                     VIVVASRAIKKQEDMEMIYKLADKLNAQVAGTRPVIEAGWIDAKKQIGLSGRTVKPKL
                     IITCGVSGAVQFVAGMQGADYIVAINKDDKAPILDVAHLALIGDIYDIIPKLIEKIEN
                     NKDNNQKYMASAAK"
     gene            complement(2819..3607)
                     /locus_tag="KR294_002573"
     CDS             complement(2819..3607)
                     /locus_tag="KR294_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003402402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HBH0240638.1"
                     /translation="MEILTCIKQVPGTTSVEVDETTGVLKRDGVDSKMNPYDLYALET
                     ALRIKEDKKANLKVLSMGPPQAKKVIEESFMMGADEGALISDRRFGGADVLATSYTIS
                     QGIKKMGKVDLIICGKQTTDGDTAQVGPEVAEFLDIPHVTNVTKLIEVKDESIVVEID
                     MPNDLQVCEIEYPCLITVEKDIFQPRLPSFKLKLNTKDREIPVYSLDDFEDKNENNYG
                     LNGSPTQVVRIFPPKPNTDKNIVRGNADELSFALVNKLEELKLV"
     gene            complement(3624..4898)
                     /gene="larA"
                     /locus_tag="KR294_002574"
     CDS             complement(3624..4898)
                     /gene="larA"
                     /locus_tag="KR294_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel-dependent lactate racemase"
                     /protein_id="HBH0240639.1"
                     /translation="MVKLKVPYSKQGMILEIPDERFLGVLESKSDNYIEHKTQEEIVE
                     ESMNNPIGSNSLEELVKGKKNVVIITSDHTRPVPSRITMPIILRRIRNVNPEIDVKII
                     VATGFHRPSTREELIYKMGEEIVDNEDIVMHISTDDKSMCKVGILPSGGDLYINKLAY
                     EAELLIAEGFIEPHFFAGFSGGRKSVLPGIASAKTIMYNHCSDFIDSDNSRTGKLNNN
                     PIHEDMVYAAKVAKLAFILNVVIDKDKKIIASFAGDVEKAHTKGCRFVTELSKVNSIK
                     SDIVVTTNGGYPLDQNIYQSVKGMTAAEATCKDGGVIIMISACNDGHGGQSFYENVAN
                     ADSPKQLLDKIRSVDRVDTIPDQWEFQILARILSKYTVIMVTDKCNPEMIKKMHMKHA
                     FNFKEALEMANSIVGKESKVVVIPDGVSVIVK"
     gene            complement(5016..5729)
                     /locus_tag="KR294_002575"
     CDS             complement(5016..5729)
                     /locus_tag="KR294_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HBH0240640.1"
                     /translation="MFNSIASKKVYEQVIEQIQYKILNGELKKGDKLLSERELSEQMN
                     VSRTSIREAIRVLETMGVIESRQGEGNFICTNIEKTLIEPLSMIFKLNNGTLEDILEL
                     RIILEIEIAKLASKRITSSEVIELKHIIDEMRVETNKKDNNRVLVLLDQKFHSKLATL
                     SKNYLIQSLFMTASKLFDGFIEDAREKIIAEPFNENILLKQHEAIYNAVVENDVELAC
                     EKAKEHMDFISKNYRKNEN"
     gene            5854..7113
                     /locus_tag="KR294_002576"
     CDS             5854..7113
                     /locus_tag="KR294_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation integral membrane protein YlbJ"
                     /protein_id="HBH0240641.1"
                     /translation="MKKNKIIAFFAPSIIVGVLVLGIILYPNEAIKSAREGFSIWSNV
                     LVPSLLPFIIGANLIVDLKIVDIIGFIINPITRFVFNVSGKSALAFAISTVSGYPVGV
                     SLASEFRSNGQISKYEAQRLVSFCSTSGPLFIIGSVGTGMFQNSNLGYLMILCHYLGT
                     ILVGLFFRNYGNENLPKTKLDLKTNIKNVINIRNSSGNGFFVLFGNAVFNGVNTLLTV
                     GGFVIVFSVVFKILSLFNVISLIASVIYLPLSFLGVSKELCQAFVSGLFEITIGCNKV
                     SSITSSPEILRASLASFLIGFSGLSILAQCCTFLSKTDIDLKLYILSKFAHGVLAAIF
                     IFILYPIANSAVLVSSFADTYNVIYNNLIWFYYLSYYDTILQIVVIIYLISAVFIAKK
                     HMKTLSTNGKLMRYKNTFFTKKFSRKK"
     gene            7393..7959
                     /locus_tag="KR294_002577"
     CDS             7393..7959
                     /locus_tag="KR294_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBH0240642.1"
                     /translation="MATRPIEIDEYKKIMELLHTGFTYSENGVEKRFRKNPKVALALM
                     LEANLGLRISDILRLKIGNFKGNMLEINEKKTGKLQYRPVNKNIIESINEHARKYNLK
                     SNDYLVNIKTKAIQKQLRIICKHLNLYNISTHSFRKLYATTQFEKSNNNLELVKELLN
                     HSSVATTQRYIRVTQQAINEASENFFIG"
     gene            complement(8160..9365)
                     /locus_tag="KR294_002578"
     CDS             complement(8160..9365)
                     /locus_tag="KR294_002578"
                     /EC_number="1.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HBH0240643.1"
                     /translation="MKIAILGYGTVGSGLIDLIENNTSKRDIEVVGILVKNKEKHKYK
                     KYFDKITTDIEDIFDKDIDILVEVIGGLNPAFDYVTRALNKKIHVVTANKDLLAEKGS
                     DLIELANLNNVSIKFEASVAGGIPVLKPLIESLEGNNIKSINAILNGTCNFILSKMYD
                     ENLPYDVALKQAQELGFAEVNPDADVLGYDSARKLSILSTLSYGKIVYWKDLLLEGIT
                     SIDEKDIEYAKKLNCKIKLVARSKYESGEVSGFVRPALVDNNNMLSKIDNEFNVVILV
                     GDSVGELSFVGKGAGRGATGSAVYADIIDIIDNRSSNIKSFSKGKLDLSGLIEDECSA
                     VVRFGGYNNKDGILECLDKYVDSYDIIDDEELAIFVSAKSEHEIDRVLEIVKRNNYSE
                     SAKKLLKID"
     regulatory      complement(9468..9574)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            complement(9666..10034)
                     /locus_tag="KR294_002579"
     CDS             complement(9666..10034)
                     /locus_tag="KR294_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhbY family RNA-binding protein"
                     /protein_id="HBH0240644.1"
                     /translation="MLKGKQRAYLRSLANTLKPTTQIGKEGVTESFLEQLDGMLRTRE
                     LVKVTILENAGLDTKETANAVCEALRAEFVQAIGFKFTIYKRNIEEPKILFPGHEQAK
                     AKTKNNNVTKKGKPTKRAVR"
     gene            complement(10086..11363)
                     /gene="obgE"
                     /locus_tag="KR294_002580"
     CDS             complement(10086..11363)
                     /gene="obgE"
                     /locus_tag="KR294_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000469293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HBH0240645.1"
                     /translation="MFIDKARIFVKAGNGGNGSVAFRREKYVPAGGPDGGDGGRGASI
                     IFEVDLGLRTLMDFKYQKKYQAQNGGDGSKGKRAGKNGENLVLKVPAGTVIRDEATGL
                     VLADLKKEGDTAIVAKGGIGGKGNQHFANAVRQAPAFAKSGTDGEERWITLELKMIAD
                     VGLLGFPNVGKSTFLSVVTKAKPKIANYHFTTLTPNLGVVQTKFGDSFVLADIPGIIE
                     GASEGIGLGHEFLRHVERTKVLIHIVDISGLEGRDPIEDFDKINDELKLYNEKLSKRP
                     QVVVANKFDILEDESKFEKFKSELEGRGYTVFKMSAATRQGIDEVIAYVSKMLKEVED
                     VELVSEEEMYRPELDIGTEEELSIDIEDGVYVVTGKALRRIMYSVNFDDMESLQYFQK
                     AMESQGVFDRLREMGIEDGDVVKIYELEFEFYN"
     gene            complement(11474..11764)
                     /gene="rpmA"
                     /locus_tag="KR294_002581"
     CDS             complement(11474..11764)
                     /gene="rpmA"
                     /locus_tag="KR294_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HBH0240646.1"
                     /translation="MLNMNLQLLASKKGVGSSKNGRDSISKRLGVKRFDGQLVTAGSI
                     IVRQRGTKIHPGTNVGKGSDDTLFALVDGTVKFERKDKKRKKVSIYPVAIAE"
     gene            complement(11778..12095)
                     /locus_tag="KR294_002582"
     CDS             complement(11778..12095)
                     /locus_tag="KR294_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HBH0240647.1"
                     /translation="MIKVKYYYNDDFLLQGFCLKGHADFAEIGYDIVCAAVTSNAIAV
                     INSLDKLQKIEFEKVVGEEGHIECIVKDTHVKDAQLLLNHFQLAVKEIKREYPKNIKI
                     LKK"
     gene            complement(12110..12421)
                     /gene="rplU"
                     /locus_tag="KR294_002583"
     CDS             complement(12110..12421)
                     /gene="rplU"
                     /locus_tag="KR294_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012063435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HBH0240648.1"
                     /translation="MYAIVKTGGKQYKVSEGDVLFVEKLEANAGDVVTLNEVLACSKD
                     GELKLGSPVVEGASVQAKVVEQGKAKKVIVFKYKAKKDYRRKQGHRQSYTKIVVEKIN
                     A"
     gene            complement(12522..13943)
                     /locus_tag="KR294_002584"
     CDS             complement(12522..13943)
                     /locus_tag="KR294_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rne/Rng family ribonuclease"
                     /protein_id="HBH0240649.1"
                     /translation="MKKIVIESLIGSQKTAVLEDERLTELFVEDNLNKKTVSNIYRGI
                     VKKVIPGIEACFVDIGFKKLAYLQLKKGSTIKSGQDILVQINKEEIGTKGAKLNTEIS
                     ISGRYIVYIPSNDRTTISNKITDEKERFRLKKITKAVNKENLGLIIRTEAQGCTHDEI
                     KKDIEELKLKYENILKEYKLGIGPKLLYKSLDFATKYVKDNVNDDIESIITNSYDKYS
                     ELKSILRGIDKTYVDKLCLEENRDVFDLYRIESKIEKLLNKKVWLKSGGYLIIEKTEA
                     LTVIDVNTGKFIGTGKLDETVYKTNLEAAKEIVRQLRIRDIAGIIIIDFIDMHKKKHQ
                     KEILHILEEEFNKDKRKAEVLGMTKLGLVEVARRREKESIDKYYLMSCPCCDGEQTIK
                     SVHYILDSIEKEIMRISEHTVYKNIMVEFNDFIFEQIKEYYMDIIDKIGEKYNIKISL
                     NANSTLKHNKTNVIFDKIVDNKM"
     gene            complement(13961..14662)
                     /locus_tag="KR294_002585"
     CDS             complement(13961..14662)
                     /locus_tag="KR294_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2344 domain-containing protein"
                     /protein_id="HBH0240650.1"
                     /translation="MSKIIRVKFKKEGDMIYISHLDLQRLLQRAFRRAEINLSHSQGF
                     NPHPKMSYGNALALGTESQGEYVDIEIEEDDLSVEEFLNKVSIQLPDGIDFIKAKEID
                     RQTPSLSSVIDYGEYLFNIDLKRPMTKEFVKRKVIDFMNNKEIIITKKNKKGKMVEVD
                     IRPMIRTFDVLNLEDEHITLTATIATGSKTNLNTNILIPKILEMFELDIDPLDVDILR
                     RDLYVLEDGELVTPM"
     gene            complement(14664..16508)
                     /locus_tag="KR294_002586"
     CDS             complement(14664..16508)
                     /locus_tag="KR294_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03960 family B12-binding radical SAM
                     protein"
                     /protein_id="HBH0240651.1"
                     /translation="MNKVDLKKILKKVEKPARYLGNEINSIHKDTSNSELIRYAHCFP
                     DLYEVGMSHLGSHILYDVINKDEDVFCERVYSPAVDMENIMREKSIPLFALESREPIT
                     NFDFVTFTLQYELSYTNILNILDLANIPILKEERTLEDPFIMVGGPCAYNSEPLADFV
                     DVVILGEGEEVNLEVVNEYKEWKKNKTTREDFLYKISSIEGVYIPSFYDVKYNEDGTV
                     QSVTPNREGITKNPTKRIIKDVETVDYPEKLIVPYIDTVHDRIVLELFRGCTRGCRFC
                     QAGMIYRPIREKSVKRLKEILDKLVKNTGYDEISLSSLSTSDYSKLSELTDYLVDEYA
                     SNNIGISLPSLRLDNFSMEIADKIQQVRKSGLTFAPEAGTQRLRDVINKGVTEEDLEN
                     ATERAFEMGWNSVKLYFMIGLPTETYEDLDGIAKLAYKVIDIYRKVNGGKLKRSFSVT
                     VSTSTFVPKPFTPFQWHGQDTTEEVINKQRHLVNKLRNNNIKYNYHDSKTSLMEAVVA
                     RGDRRIGKVIYDAFRLGAKFDGWAEHFNLDIWKEAMEKNNLSIDFYAHRNRNYEEVFP
                     WDHIDVGISKKFLIREDENAKKEKITSDCRHNCNGCGINIHDIGRGLC"
     gene            16827..18020
                     /locus_tag="KR294_002587"
     CDS             16827..18020
                     /locus_tag="KR294_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FprA family A-type flavoprotein"
                     /protein_id="HBH0240652.1"
                     /translation="MSKVFEVKKDIYFTGVVDEGLKVFDIIMETEFGTTYNSYLIKDE
                     KTVLFDTVKANFKDEFLSNLSEVTDIAKIDYVVIHHTEPDHAGSLKYLLDINPNIEVY
                     CTKAAKLYLDGQINRPFNCHVIKDGEILNIGKRNLRFITAPFLHWVDTMFTYIEEDKT
                     LLTCDAFGCHFASVDAEVVNSEDYLKSAKHYYDCIVKPFAKHVLSAVDKVVGLNIEFD
                     TILTSHGPMLTKDPMAAVKRYVEWSTEAVNTTNQNQVSIFYLSAYSNTLEMAKKIKEG
                     LDKEGAKAELYDLEDMTLTEMHDTLVVSKVILLGSPTINKTMVKPMWDLFSVIDPMAN
                     QGKIAGVFGSFGWSGEGITMAETLLKSMSFKMPVESLKKKFFPSEETLKECMAFGAEF
                     AKLVK"
     gene            complement(18232..19314)
                     /locus_tag="KR294_002588"
     CDS             complement(18232..19314)
                     /locus_tag="KR294_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="HBH0240653.1"
                     /translation="MKKIRKLATKLLIAMMVLTSCMSVTVYGMTAKDVTAKTPKSYVA
                     GTNSIYGPKLSQAQLNSVAQATADFMNKKITKNMTTDAKIRVAYNHIKNNTTYVNWNA
                     AEGANTAYTLVTKKGACSGMCRSLKALCDAMGIECYYVHSTTNDHQWNLIRFEDGRLY
                     HVDIDANKSAGADIIYKSLTHPLPFDKKAYPAVGEVVKTQNPTPTVKKPTPAKPSAPV
                     GPGNHTMIADQQGAILDEVYGNNLRPKIEMYEGVPCSLINSSINTIKFTSKNSNLDPS
                     KHTVTVIGFMNTPYGMVALAPDGVPDEYPFEYDKPFSLDFTGKNLSAAELSKKCKENN
                     VIIKVEIGETASNSGRGMVAYARYVN"
     gene            complement(19878..20669)
                     /locus_tag="KR294_002589"
     CDS             complement(19878..20669)
                     /locus_tag="KR294_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240654.1"
                     /translation="MKLIDEYLDKLYKKCDNKSTIELKQEMRCHLIESANEFKLEGLD
                     EEEACKKAIERFDDGDEMQYELCNIIKELSLSLDRHKSIVMGFKKVLGYISIIAFLIS
                     GFMWYYNNSLQHNMYNLGKELDGEIKQLAERHDMTKIGEYKLELEKILDKDKYSKVKA
                     LRLYVIDMKDGNTNLSSSGLNANMVYEREADYNNISNFIQHLGYNGKDFLDKNGNIVN
                     PDIFLEYFFYFESEMLIPVAFAFGLLCIIAYFILRFKISLIKNNN"
     gene            complement(20673..21002)
                     /locus_tag="KR294_002590"
     CDS             complement(20673..21002)
                     /locus_tag="KR294_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0240655.1"
                     /translation="MQLNKEVLKGYIDILIVSILEKKDCYGYEIAKQVRERSEFELKE
                     GTMYLALKRMESKNLIKSYYSNEQSSGGRRKYYNLTNEGKDFLEIKKQEWRFIKKVMN
                     QFLGEVD"
BASE COUNT         6642 a         3814 c         2347 g         8282 t
ORIGIN      
        1 gtacacatgc ttttaggatg acaacatcaa cttaaatatt atgttacttt ctaaatttaa
       61 gtaaatattg ccatcctaaa aattttacaa tttagcttca gatttaaaag taaagtttaa
      121 aatattatat ttaaatctaa tttaatattt tttgttttgt aaatattatt aaattaatat
      181 ttctaatata ttttccctgg atttaaaata tttttagggt caaaagctaa ctttatattt
      241 ttaattaaca tcatataagc atctgaattt gattcatgta agtactcttt tttagcatat
      301 cctatgccat gttcaccaga aacttgacca ctaagttctc tagatttttt atacatatag
      361 tcaaaagttt cttttaatct tattttccat gtattatcat ccataccatc ttttaaaata
      421 tatatgtgta gatttccatc tcctgcatga ccaaaacttt ttattcttat ttttaatttg
      481 tcttgaagct cgtgagtgta tcttataaac tctgctatct tatctcttgg aacaacgaca
      541 tcacattcat ccatttgtgt cgtagatgcc tttatagctt ctaaaaatgc acctctggct
      601 gaccatatag aatcgtttct ttcttgtgta tctgatataa atacatctaa tgcaccattt
      661 tctaaacata aattagctac tttttcatat tctttttcta tatcttcagt gctatttcca
      721 tcaaatgtaa gcaaaagata agcatctgat gtattatctg gaaacttttt acctaaaaat
      781 tcttctgctg ccaatatcac atctctttcc ataaattcta tagccgttgg tattgatttt
      841 gattttatta ttttaggaac agtttctatt gccattgata aatctggaaa tggtataagc
      901 aaacttatac ttttctttgg taaaggaagc aattttaata tagctttagt aactattcct
      961 aaagtacctt ctgagcccac taataaatcc tttatactat atccagaact atttttaacc
     1021 acctttccac ctacatttat aatttctcca tttggtagta caacttcaag acctcttaca
     1081 taatcccttg taacgccata ttttactgct ctcataccac ctgcattagt gtttatatta
     1141 cctgcaattg tagcactttt ttcacctggg tcaggtgggt aaaataaatc tctatcttga
     1201 acatattgac ctattgtcat caataaaaca cctggttcta ctgtcaatgt taaattttca
     1261 taatcaactt caagtatttt attcatttta catagattaa tcattattcc accatttatg
     1321 gcaacagcag cacctacaag accagtacct tgacctcttg gtgtgactgg tatattattt
     1381 ttatatgcgt atttcattat tttagatact tgttcagttt caagtacatt tactaaaact
     1441 tcagggtact tctcaatccc tccaagttca tcatgtgaaa aatcttcatt tatatcactt
     1501 ccaactaata cattttcttc tccacaagta tctattaaaa aatctatatc ttttttatcg
     1561 attaatttat acatttctat ccccctattt agctgctgat gccatatatt tttgattatt
     1621 atctttgtta ttttctattt tttcaatcaa tttaggaata atatcataaa tatcacctat
     1681 taaagctaaa tgtgctacat caagtatagg cgctttatca tctttattta ttgctactat
     1741 atagtcagca ccctgcatcc ctgcaacaaa ttgaacagct ccagatacac cacaagttat
     1801 tatcaattta ggttttacag ttctaccact aagacctatt tgttttttag catctatcca
     1861 acctgcttct attacaggtc ttgttcctgc cacttgagcg tttaacttat cagctaattt
     1921 atatatcatc tccatatctt cttgtttttt tattgctcta cttgccacaa ctatcacttc
     1981 agcttcttcc agaccaactt ctttattttt ttcttttaca ctcagtacct taattttaga
     2041 ttttagttct tttttttcta ctttacataa agttatcttt cctgtagtat tctctatttt
     2101 ttctggtgct gaaaatattt tatatcttac agtggcaaat tgtggtctat tattaggtgt
     2161 gtttatatga gccattatat ttccaccaaa tgctggtctt atttggtcta aatcagtatt
     2221 tgattgaata tcaagtattg tacaatctgc tgtaagacct gttctaaatc tagcggcaag
     2281 tcttggagct aatgacctac ctaatgtagt tccaccaact aatactatcg ttggttttat
     2341 tttatctata aagttttcta ttgcttttga atatggttct atcctaaaat ctttaaattc
     2401 atcttcatca tatacaaata cttcatccac cccataagaa atcaaattac tgcacttatc
     2461 ttttatgtct tttcctacaa atacacaata cacaggttgt tttatttttg atgccatctc
     2521 acgagcttta cctataagct cgtacgttac aggatgtata tttccattat gatgttcaac
     2581 atatactgca attcccctcc attcatcttt attaatttgt actttactac tctctataaa
     2641 ttcaaatgcg ccttttggtc cacttttgac acacaacttg cacatcttac agccagcact
     2701 tatttctact atacctgact tttcttctat agccccaaaa ggacatattt ctaaaattct
     2761 ctttaagtca gttattttat cttgatttac aactatcttt gacatttatt actccccctt
     2821 acaccaactt taattcctct aatttattta caagtgcaaa acttagttca tctgcatttc
     2881 ctcttacaat atttttatct gtatttggct ttggaggaaa tattcttaca acttgagtag
     2941 gagaaccatt aagtccatag ttattttcat ttttatcttc aaagtcatct aagctatata
     3001 caggtatttc tctatcttta gtattaagtt ttaatttaaa tgaaggtagt cttggttgaa
     3061 aaatgtcttt ttctacagtt attaaacatg gatattcaat ctcacatact tgtaaatcat
     3121 ttggcatatc tatttcaaca actatacttt catctttaac ttcaattaat tttgtaacgt
     3181 tagtaacatg aggtatatct aaaaattcag ctacttcagg tcccacctgt gctgtatcac
     3241 catcagtagt ttgttttcca caaattatta ggtctacctt tcccatcttc ttaatacctt
     3301 gtgatatggt ataggaagta gccaatacat ctgctcctcc aaatctccta tcacttatta
     3361 atgctccttc atcagctccc atcataaaac tttcttcaat taccttcttt gcctgaggag
     3421 gacccatgct aagtactttt agattcgctt tcttatcttc ctttattcta agagctgttt
     3481 ctaaagcata taggtcatag ggattcattt ttgaatctac tccatctctt tttagtactc
     3541 ctgtagtttc atcaacttct actgaagtcg ttccaggaac ttgtttaata catgtcaaaa
     3601 tttccataaa gtacactcct tttttattta actataactg atactccatc aggtataact
     3661 actactttgc tctccttacc aactatacta ttcgccattt ctaaagcttc tttaaagtta
     3721 aatgcatgtt tcatatgcat tttttttatc atttcaggat tacacttatc tgttaccatt
     3781 atcacagtat atttagataa tattctcgct agtatctgaa attcccattg gtctggaatc
     3841 gtatctactc tatcgacact tctaatttta tctaaaagtt gttttggaga atctgcattt
     3901 gctacatttt cataaaaaga ttgacctcca tgaccatcat tacatgctga aatcattatt
     3961 attactccac cgtctttaca agtagcttca gctgctgtca ttcctttaac agattgataa
     4021 atattttggt ctagtggata tccaccattt gtagttacaa caatatcaga ttttatagaa
     4081 tttacttttg ataactctgt tacaaatcta catcctttag tatgtgcttt ttcgacatca
     4141 ccagcaaagg aagcaattat ttttttatct ttatctatta caacattcaa tatgaatgct
     4201 aattttgcaa ctttagctgc atataccata tcctcatgaa taggattatt attcaatttt
     4261 ccagttcttg aattatcact atctataaag tcactacagt gattgtacat tatagtcttt
     4321 gcagatgcga ttcctggaag tacgcttttt ctgccacctg aaaaacctgc aaagaaatga
     4381 ggttctataa aaccttctgc tatcaaaagt tctgcctcat atgctagttt gtttatatat
     4441 aaatctccac ctgaaggcaa tatccctact ttacacatag atttatcatc agtagatata
     4501 tgcataacta tatcttcatt atctactatt tcttctccca ttttataaat tagctcttcc
     4561 cttgtacttg gcctatgaaa tccagttgcc actataatct tcacatcaat ttctggatta
     4621 acattcctaa tccttcttaa tataattggc atagttattc tacttggtac aggtcttgta
     4681 tggtcacttg taattatgac tacattcttt ttccccttaa ccagttcttc cagagaatta
     4741 gagcctatag gattattcat agattcttca actatctctt cttgagtctt atgttctata
     4801 taattatccg attttgactc caaaacaccg agaaaacgtt catcaggtat ttctaaaatc
     4861 attccttgtt ttgaatacgg tacttttaac tttaccattt ttaatctccc attataataa
     4921 actataaaat tggtatgtgg tcataccagt tttacattta tataatagta ccattatcta
     4981 ccatttgcaa gaataattta ttttataaca aacttttaat tttcattttt tctataattt
     5041 ttacttataa aatccatatg ttcctttgct ttctcacatg caagttctac atcattttct
     5101 acaactgcat tgtatatagc ttcatgctgt ttaagcaata tattttcatt aaaaggttct
     5161 gcgattattt tttctcttgc atcttctata aatccatcaa ataattttga tgctgtcata
     5221 aaaagacttt gaattaaata atttttactt aatgttgcta gtttactgtg aaatttttgg
     5281 tctaataata ccagtactcg attattatct tttttattag tttctaccct catttcatct
     5341 attatatgtt tcaattctat aacttcagaa gaagttattc tctttgaagc aagttttgca
     5401 atctcaattt ctaggattat tctaagctct aatatatctt caagtgtacc attattaagt
     5461 ttaaaaatca tagataaagg ttctattaaa gttttttcta tatttgtaca tataaaattt
     5521 ccttcaccct gtctgctttc tatcactccc atagtctcta ataccctaat agcttccctt
     5581 atggaagttc tactcacatt catttgttca gacagttctc tttctgatag taatttatcc
     5641 ccctttttta actctccatt tagtatttta tattgtattt gctcaattac ttgttcataa
     5701 acttttttac tagctatact attaaacatt ttttcctcca atatgataat cgttgttgta
     5761 atatatatct attatatatc ttaagccatt acattcatat atttttatta cttttaatat
     5821 aatatcttat aactcaaatt tacaggtgat attatgaaaa aaaataaaat tattgctttt
     5881 tttgctccat ctatcatagt tggagttcta gttttaggga ttatcctata cccaaatgaa
     5941 gctataaaat ctgcaagaga aggcttttct atatggtcta atgttttagt tccatcacta
     6001 ctaccattta taattggagc aaacttaatt gttgatttaa aaatagtgga tattataggg
     6061 tttatcatca atcccataac tagatttgta tttaatgttt caggaaagag cgctttagct
     6121 tttgctatat ctacagtatc tggttatcca gtaggagtaa gtttagcttc tgaatttagg
     6181 agtaatggac aaatttctaa gtatgaagca caaagacttg tgtctttttg ttctacatca
     6241 ggacctttat tcataatagg ttcggttggt acaggtatgt tccaaaattc aaacttaggt
     6301 tatttaatga ttctctgcca ttatctagga actatattgg ttggtctttt ctttagaaat
     6361 tatggtaatg aaaaccttcc aaagacaaaa ttggatttaa aaacaaatat aaaaaatgta
     6421 atcaacatta gaaattcaag tgggaatggt ttttttgttt tatttggaaa tgctgtattt
     6481 aatggagtaa acacattact tacagttggt ggatttgtaa ttgttttttc agtagtattt
     6541 aaaatactat ctctttttaa tgtaatctca ttaatagcat cagttatata tttgcctctt
     6601 tcatttttag gtgttagtaa agaactctgt caagcatttg taagtggtct atttgaaatt
     6661 actataggat gcaataaagt atctagtata acaagttctc cagaaatttt aagagcatct
     6721 ttagctagtt ttttgatagg atttagtgga ttatccatcc tagctcaatg ttgtacattt
     6781 ctatcaaaaa cggacataga tttaaaatta tacatactaa gtaaatttgc gcatggagtt
     6841 ttagctgcta tctttatatt tatactttat ccaattgcaa actctgctgt gttggtttct
     6901 agctttgctg atacatacaa cgttatatat aataatttaa tctggtttta ttaccttagc
     6961 tattatgata caattcttca aattgtagta ataatttatc taatctcagc cgtatttatt
     7021 gcaaaaaaac atatgaaaac tttatctaca aatgggaaac taatgcgata taaaaatact
     7081 tttttcacta agaaattttc acgaaaaaaa taaaactaaa aataaaacta ataaaactta
     7141 actaaatact tccatttttt tattatattt gtcataattt taataacctt tttaattagt
     7201 ttaacagcat agttatttca tcacaattta ataattttat tagaaatatt tttcaaaaaa
     7261 ttctccttaa tcacatatat cacacttgta taagtttact gggaaatttt tccattatat
     7321 aatatttcat ttatattata taataaatac cgacctaaac ttaccaaatc aaactaagag
     7381 gagtggttga aaatggcaac aagacctata gaaatagacg aatataaaaa gataatggaa
     7441 ctattacata ctggctttac ttatagtgaa aatggcgttg aaaaaagatt tagaaaaaat
     7501 cctaaagttg cattggcact aatgttagaa gctaatttag gtctaagaat atcagatatt
     7561 ttaagattaa agataggtaa ttttaaaggt aatatgttgg aaataaatga aaaaaagacg
     7621 ggcaaattac agtatagacc agttaataaa aatataattg agtccataaa tgaacatgca
     7681 agaaagtata atcttaaatc aaatgactac ttagtaaata taaagacaaa ggctattcaa
     7741 aaacagttga ggataatttg taaacactta aatctgtata atataagtac acatagcttt
     7801 agaaagctct atgctactac tcaatttgaa aagagtaaca ataatttaga gttggttaaa
     7861 gaacttttaa atcacagctc tgtagccact acacagcgat atataagggt aactcagcaa
     7921 gctattaatg aagctagtga aaatttcttt attggttaat tataacgtat acatttttct
     7981 attatcttat taattcacca gatattaaaa aagagtgtct caaaatgaac tttttagttc
     8041 ataagacact ctttttttat aaaatcaaat atatttttat tatttcaaca ctggaaaaaa
     8101 ggcttatctc tctattttga gacaccctat taaattttca taattcttgc ataaacatat
     8161 taatctatct tcaataattt tttagctgat tcactgtaat tatttctttt tacaatttcc
     8221 aaaactctat caatctcatg ttctgacttt gcacttacaa aaatcgccaa ttcttcatca
     8281 tctataatat cataactatc tacatattta tctaaacatt ctaaaattcc atctttatta
     8341 ttatacccac caaatctaac tactgcacta cactcatctt ctataagtcc acttaaatcc
     8401 aatttccctt ttgaaaaaga ctttatattt gaacttctat tatctattat atctataata
     8461 tctgcataaa cagcacttcc tgttgcacct cttccagctc ccttacctac aaaagaaagt
     8521 tcacctactg aatcacctac taaaataact acgttgaact cattatctat ctttgaaagc
     8581 atattattat tgtccactaa tgctggtcta acaaatccac ttacttctcc tgattcatac
     8641 ttacttctag caaccaattt tatcttacaa tttaattttt ttgcatattc tatatctttt
     8701 tcatctattg aagttattcc ttctaataat aaatctttcc aatatactat ttttccataa
     8761 gataaagtag acaatataga taactttcta gcactatcat atcctaaaac atctgcatct
     8821 ggattaactt ctgcaaatcc caactcttgt gcctgtttta aagcgacatc atacggtaaa
     8881 ttttcatcat acatctttga taatataaaa ttacaagtcc catttaaaat agcgtttatg
     8941 ctctttatat tgttgccttc cagtgattct atcaatggtt ttaaaactgg aataccacct
     9001 gccacagatg cttcaaactt gatgctaaca ttatttaagt tagctaattc tataaggtca
     9061 ctaccttttt cagccagtaa atctttatta gctgtcacta catgtatttt tttatttaac
     9121 gctcttgtta cataatcaaa agctggattt aatcctccaa ttacttcaac tagtatatca
     9181 atatccttgt caaatatatc ttctatatca gtagttatct tatcaaagta cttcttatac
     9241 ttgtgttttt ctttattttt aactaaaatt ccaacaactt ctatatctct ttttgaagta
     9301 ttattttcta ttaaatcaat taatccactt cctactgttc cataccctaa tattgctatc
     9361 ttcactgtaa cataccccca tcattttgat tatattaaat tatttatata tataaatata
     9421 ccaataaaaa aagcttgagt ataaactcaa gccatatgac gggtttatac tcatctttca
     9481 gcataaatgc tgcaggattt agcaccaatg tataattaaa tatactggtt gccgggcttc
     9541 acagggccag tccctctgcc actcttgata agattgctaa tttaaattta tgtttaatag
     9601 tataatacaa tttcttccaa ttgtcactat ttttttaact tatttcccta aaaggatata
     9661 aactattatc taacagctct tttagttggt ttaccctttt ttgtaacatt attattttta
     9721 gtctttgctt tcgcctgttc atgtcctgga aaaagtattt taggctcttc aatattcctc
     9781 ttgtaaatag taaatttaaa accaatagcc tgcacaaatt cagctcttaa agcttcacat
     9841 actgcattag cagtttcttt agtatcaaga cctgcatttt ctaatatagt aacttttact
     9901 aattctctag ttcttaacat accatctaat tgctctaaga aactctctgt aacaccttct
     9961 ttaccaattt gtgtagtagg ctttaaagta tttgccaaag atcttaaata cgccctttgt
    10021 tttcctttta acatattctc acctctataa ttctatactt aaattatcta taatctatat
    10081 ttaaattaat tgtaaaactc aaattctaat tcataaattt taaccacatc tccatcttct
    10141 attcccattt ctctaagcct atcaaaaaca ccttgactct ccatagcttt ttggaaatat
    10201 tgaagggatt ccatatcatc aaaatttaca gaatacatta ttcttctaag tgctttacct
    10261 gtaactacat acacaccatc ttcaatatct atacttaact cttcttcagt accaatatca
    10321 agttctggtc tatacatttc ttcttctgaa actagctcca catcttctac ttcttttagc
    10381 attttagaaa cataggctat tacttcatct atgccttgac gagttgctgc tgacatttta
    10441 aatactgtat atcctctgcc ttctaattca ctcttaaact tctcaaactt actctcatct
    10501 tctaatatat caaatttatt tgcaactaca acttgtggtc tctttgaaag cttttcattg
    10561 tacaatttaa gctcatcatt tatcttgtca aaatcttcaa tagggtctct tccctctaat
    10621 ccagatatat ctacaatatg tatcaatacc tttgttctct caacatgtct taagaactca
    10681 tgacctaatc ctatgccttc agaagcaccc tctataattc caggtatatc tgcaagtaca
    10741 aaactatctc caaacttagt ttgaacaaca cctagatttg gtgtaagtgt tgtaaaatga
    10801 tagtttgcaa ttttgggttt agctttagtt acaactgata gaaatgttga tttacctaca
    10861 tttggaaatc ctaaaagacc aacatctgct atcattttaa gttcaagagt tatccatctt
    10921 tcttctccat ctgtaccaga ttttgcaaaa gctggagctt gtcttactgc atttgcaaag
    10981 tgttggttac ctttaccacc tataccacct tttgcaacta tagctgtatc tccttctttt
    11041 tttaaatctg ctaatacaag acctgtagcc tcatctctta ttactgtacc tgctggtact
    11101 tttaatacta aattttctcc atttttacca gctctttttc ctttgcttcc gtcgccacca
    11161 ttttgagctt gatatttttt ctggtactta aagtccatta gagttctaag ccccaaatca
    11221 acttcaaata tgatgcttgc tccacgacca ccatctccac cgtctggacc accagctgga
    11281 acgtattttt ctcttctaaa tgctaccgaa ccatttccac catttccagc cttaacaaat
    11341 attcttgcct tatctataaa caaattcttc acctacttaa ttaaaaactt ttaattagca
    11401 ttaccaaaaa taccattata aattcatcag tattataaga aaaaggagtg cctcaacact
    11461 ccttttatgt atattactca gctatagcta ctggatatat actaactttt tttctcttct
    11521 tgtcttttct ttcgaattta acagtaccat caactaatgc aaataaagta tcatcactac
    11581 cttttccaac attagttcct ggatgtattt tagttcctct ttgtctaact attatacttc
    11641 cagcagttac taattgacca tcgaatctct taacacctaa tcttttagat atagaatctc
    11701 taccattttt agaagaacct accccttttt tagatgctaa taattgtaaa ttcatgttta
    11761 acatatggag tcacccccta cttttttaaa atttttatat tttttgggta ttcccgttta
    11821 atttctttaa ccgctaattg aaagtgattt agtaataatt gtgcgtcttt tacatgtgta
    11881 tctttgacta tacactctat atgaccttct tctcctacta ctttttcaaa ttcaatcttt
    11941 tgtaatttgt ctaaagaatt tataactgca atagcattag atgtaactgc agcacatact
    12001 atatcatagc ctatttcagc aaaatcagca tgtcccttta aacaaaaacc ttgcaacaag
    12061 aaatcatcat tataataata tttaactttt atcataactt aaccaataac taagcgttta
    12121 ttttttctac aactatctta gtgtatgatt gacgatgtcc ttgttttctt ctgtaatctt
    12181 tttttgcttt atacttgaaa actataactt tcttagcttt accttgttca acaactttag
    12241 cttgaacaga tgctccttct actactggag aacctaattt taattctcca tctttagagc
    12301 aagctaatac ttcgtttaaa gtaacaacat cacctgcgtt agcttctaat ttttcaacga
    12361 ataatacatc accttcagaa actttatatt gctttccacc agtctttact atagcgtaca
    12421 ttaaatacac ctcctcggcc tcaaactcgc cagtacaagg tacttcattt gaagatttaa
    12481 acctttactg tgcggcatta caattattaa ttataaaata tttacatttt attgtcaact
    12541 attttatcga aaataacatt ggttttattg tgctttaatg tactatttgc gtttaaagaa
    12601 atctttatat tatatttttc accaatttta tcaattatat ccatataata ttcttttatt
    12661 tgttcaaaaa taaaatcatt aaattctacc attatgtttt tgtaaacagt atgttcactt
    12721 attctcataa tttctttttc aatactatct agtatataat gtacagattt tattgtttgt
    12781 tcaccatcac aacatggaca agacattaaa taatacttat caatggattc tttttctcta
    12841 cgcctagcaa cttctactaa accaagtttt gtcataccta atacttcagc ttttctttta
    12901 tctttattaa attcttcttc taggatgtgt aaaatctcct tttgatgctt ctttttatgc
    12961 atatcaataa aatcgattat tattatccca gctatgtctc taattctaag ctgtcttaca
    13021 atttcttttg cagcttcaag attagtttta taaacggttt catcaagttt accagttcca
    13081 ataaacttac ccgtatttac atctataacc gtaagagctt ctgttttttc aattattaaa
    13141 taacctccac tctttaacca tactttttta tttaataatt tttctatttt agattctatt
    13201 ctgtataaat caaatacatc tctattttcc tcaagacaca gtttatcaac ataagtctta
    13261 tctatacctc ttaaaataga cttaagttca gagtacttat cataactatt ggtaattata
    13321 gattcaatat catcattcac attatctttt acatatttag ttgcaaaatc taaagactta
    13381 tataataatt tcggacctat accaagttta tattctttta aaatgttttc atactttaat
    13441 ttcaactctt ctatatcttt ctttatttca tcatgagtgc aaccttgagc ctcagtcctt
    13501 attattaatc ctagattttc cttatttact gccttagtaa ttttttttaa tctaaatcgt
    13561 tctttttcat cagtaatttt atttgatatt gtagttctat cattggaagg tatatagaca
    13621 atataccttc cagaaatact aatctcagtg tttaattttg cgcctttagt tcctatttct
    13681 tctttattta tctgaaccaa aatatcctga ccagatttta tagtacttcc cttttttaat
    13741 tgtaaataag caagtttctt aaatccaata tctacaaaac aagcttctat tcctggtata
    13801 acttttttta cgattccacg atatatattg gatacagtct tcttatttaa attgtcttca
    13861 acaaaaagtt ctgttaatct ttcatcttca agtactgctg ttttctggga ccctattagg
    13921 gactcaataa ctatcttttt cacaacttca cctctcgagc ttacatagga gtcactaatt
    13981 ccccatcttc taatacatat aaatctcttc tcaatatatc aacatctaat gggtcaatat
    14041 caagttcaaa catctctaat atctttggta taagtatatt agtatttaaa ttagtttttg
    14101 agcctgtagc tatagtagca gtaagagtaa tatgttcatc ttctaaattt aaaacatcaa
    14161 aggttcttat cataggtctt atatctactt caaccatctt acctttttta ttcttttttg
    14221 ttatgattat ttctttatta ttcataaagt caattacttt tctttttaca aactctttcg
    14281 tcataggtct tttcaaatct atattaaaca aatattctcc atagtctatc acagaagaaa
    14341 gagaaggtgt ttgtctatca atttcttttg ctttgataaa atctatccca tctggaagtt
    14401 gaattgatac tttatttaaa aattcctcta ctgataaatc atcttcttct atttcaatat
    14461 ctacatactc accttgactt tctgtcccta aagccaaagc attgccataa ctcattttag
    14521 ggtgaggatt aaatccttga gaatgtgata agtttatttc agctcttcta aacgctcttt
    14581 gtaacaatct ctgaaggtca agatgtgata tatatatcat gtcgccttcc tttttaaatt
    14641 ttactcttat tatcttactc atattagcaa agcccccttc ctatatcatg tatatttatt
    14701 ccacaaccat tgcagttatg tctacaatca gaagtgattt tttctttttt agcattttcg
    14761 tcttctctaa ttaagaattt tttactaata cctacatcta tatggtccca aggaaatacc
    14821 tcttcatagt ttctatttct atgtgcataa aaatctatag aaagattatt cttttccata
    14881 gcttctttcc atatatctaa attaaaatgt tctgcccatc catcaaattt agcacctagt
    14941 ctaaatgcat catatataac ttttcctatt cttctatcgc ctctagctac tactgcttcc
    15001 atcaaactag tctttgaatc atgataattg tattttatat tgttatttct taatttattt
    15061 actaaatgtc tctgcttatt aataacttct tctgtagtat cttgaccatg ccattggaaa
    15121 ggtgtaaatg gctttggtac aaatgtagaa gtactcactg taacactaaa acttctcttt
    15181 agctttcctc catttacttt tctataaata tcaataactt tataagctaa tttagctata
    15241 ccatctaaat cttcataagt ctcagttggt aaaccaatca taaaatacaa cttaacacta
    15301 ttccacccca tctcaaaagc tctttctgtt gcattttcca aatcttcttc tgtaacacct
    15361 ttatttataa catctctaag tctttgagtt cctgcttctg gagcaaaagt aagtccagat
    15421 tttcttactt gttgtatttt atcagcaatt tccattgaaa aattatctaa tctaagggat
    15481 ggaagcgaaa tcccaatatt attagatgca tattcatcta ccaaataatc agtcaactct
    15541 gataacttac tataatcact cgtactaagt gatgataatg atatttcatc atatccagta
    15601 ttcttaacta atttatctaa tatttcttta agtcttttaa cactcttttc tcttattggt
    15661 ctgtatatca tacctgcttg acagaatcta catcctctag tacatcctct aaataattct
    15721 agtactattc tatcatgaac agtatctata taaggtacta ttagtttttc tggataatct
    15781 acagtctcaa catcttttat tatcctttta gtaggatttt tagtaatccc ttctctatta
    15841 ggagttacac tttgaactgt accatcttca ttgtacttga catcataaaa acttggtatg
    15901 tatactcctt ctatgctaga tattttatat aaaaaatctt ctctagtcgt tttatttttc
    15961 ttccattctt tatactcatt tactacttct aaattaacct cttcaccttc acctaatatt
    16021 actacatcta caaaatctgc taatggttcg gaattataag cacaaggacc accaaccatt
    16081 ataaatgggt cttccaaagt tctttcttct tttaatattg gtatattggc taaatctaat
    16141 atatttaaga tattagtgta tgaaagttca tattgaagtg taaaagtgac aaaatcaaag
    16201 tttgttatag gctctcttga ctctaatgca aataatggta tacttttttc tctcattata
    16261 ttttccatat caactgcagg agaatacact ctctcacaaa atacatcttc atccttattt
    16321 attacatcat ataatatatg actccctaag tgactcatac caacttcata taaatctgga
    16381 aagcaatgtg catatcttat caattcacta ttactagtat ctttatgaat tgaatttatt
    16441 tcatttccaa gatatctagc aggcttttct acttttttta agattttttt caagtctact
    16501 ttattcattt attaaaattc ctccaaacaa gctctttatt tttattctta tttataagta
    16561 atattataca cgataaaata ttttctatca aaaatataac taaaatattg aatttaaaat
    16621 acatattatt cacaaaatag aatagctaaa aatatttaag aatattttct attaaatttt
    16681 tattgaaata caattttttt acaaagtatg atatattata aacataaaac tattgtttta
    16741 catgacttat catgacatct tttgtttcat tcacctcaaa atggggtatg ttacttatat
    16801 aatgataaat tttaggaggg ttaaaaatga gtaaagtttt tgaagtaaaa aaagatatct
    16861 actttactgg agtagtagat gaaggtttaa aagtattcga cataataatg gaaactgagt
    16921 ttgggacaac ttacaactct tatttaatca aggacgaaaa aacggtttta tttgacactg
    16981 taaaggcaaa ttttaaagat gagtttttaa gtaatttatc agaggttact gatatagcta
    17041 aaattgacta tgttgtaatt catcacacag aaccagacca tgcaggtagt ttaaaatact
    17101 tattagatat aaatcctaat atagaagttt attgtactaa agctgctaaa ctatacttag
    17161 atggtcaaat aaatagacct tttaactgtc atgtaataaa agatggtgaa attttaaata
    17221 tcggtaaaag aaatcttaga tttataactg ctccattctt acattgggtt gatacaatgt
    17281 ttacttacat tgaggaggac aagactcttt taacttgtga tgcatttggt tgtcactttg
    17341 caagtgttga tgcagaggta gtgaatagtg aagattatct aaaatcagct aaacactact
    17401 atgattgtat agttaagcca tttgctaaac atgttttaag tgctgtagat aaggtggtag
    17461 gactaaacat agaatttgat actatattga cttctcatgg tccaatgctt actaaagacc
    17521 caatggctgc tgttaaaaga tatgttgagt ggtctacaga agctgttaat acaactaatc
    17581 aaaatcaagt ttctatattc tacttatcag cttatagtaa tactttagag atggctaaaa
    17641 agataaaaga aggacttgat aaagaaggtg caaaggctga attatatgat ttagaagata
    17701 tgacattaac agaaatgcac gatacattag tagtgtcaaa agtaatatta ctaggttctc
    17761 caactataaa caaaactatg gttaaaccta tgtgggattt attctctgtt atagacccaa
    17821 tggctaacca aggcaagata gcaggagtat ttggttcatt tggttggagt ggtgaaggta
    17881 taactatggc tgagacttta cttaaatcta tgtcattcaa aatgcctgta gaatctctta
    17941 agaaaaaatt cttccctagt gaagagacat taaaagagtg tatggcattt ggtgcagaat
    18001 ttgcaaaatt agttaaatag ccattaatca aacataatat tatttaaaat aaatgatttt
    18061 atatttaaaa ataaattaaa atggagttgt ctcaaaatta atttttctaa tctaatttta
    18121 agttcaactc cttttttatt ttctaaaatg actgatataa tgataaatgc accctttgtg
    18181 cgagggtgca ttatttataa tatgttctat ttgtacacta gtatatttgt attaattcac
    18241 atatctagcg tatgctacca tccctcttcc agaattagat gccgtttcac caatttccac
    18301 tttaataatt acattatttt ctttacactt ttttgataat tctgctgcag aaaggttctt
    18361 accagtaaaa tctaaagaaa atggcttatc atattcaaaa ggatactcat caggtacacc
    18421 atctggagct aatgcaacca taccatatgg tgtattcata aaccctatta cagtaactgt
    18481 atgctttgat gggtctaaat ttgaattttt gcttgtaaac ttaattgtat ttattgatga
    18541 gttgattaaa ctacacggaa ctccctcata catttcaatt tttggacgta gattatttcc
    18601 ataaacttca tcaagtattg ccccttgttg atctgctatc atagtgtgat tcccaggtcc
    18661 aactggcgca gaaggcttag ctggcgtagg tttcttaaca gttggcgttg gattctgtgt
    18721 ctttactact tcgccaacag ctggatatgc tttcttgtca aatggtaatg ggtgagtaag
    18781 actcttgtat atgatgtctg ctcctgctga tttgttggca tcaatatcta catgatacaa
    18841 acgtccatcc tcaaaacgaa taagattcca ctgatggtca tttgttgtac tatgtacata
    18901 ataacattca attcccatag catcacataa agctttcaag ctcctacaca ttccagaaca
    18961 agcacctttt ttagtaacca atgtataagc agtattggct ccctctgctg cgttccagtt
    19021 aacatatgtt gtgttgtttt taatgtgatt ataagcaacc ctaatcttag catctgtggt
    19081 catgttcttt gtaattttct tgttcataaa gtctgctgtt gcttgtgcta ccgaattaag
    19141 ttgagcttgt gataactttg gaccatatat actgttggtt ccagctacat aacttttcgg
    19201 tgtctttgca gtaacatctt tagctgtcat accataaact gttacactca tacatgaggt
    19261 taaaaccatc attgcaatca atagtttagt agctaatttc ctgatttttt tcatattagc
    19321 attctccttt ataatatatt ttactttcaa ttccctacca ttaattaagt tcattttaga
    19381 tttaaaatat ggattatcaa catgtatgca tagcaattca cgtggtcata gaatatttag
    19441 atttcttgga aaatctgttc tatatttcct atatagttcg tatacaatcc aactcacaaa
    19501 cctgcatttt tgatatcatc acaataaaat gataataatt aatatattca aaaatgttgg
    19561 tctgtaacag gtatgtcaat tttccaatta ttggtaatgg cgagagtgag gagaattgtc
    19621 aataatacat ttaaaattaa aattgtatac acttcataca ttctccccta acaacattat
    19681 acagattata atttgtatat tcaatacatt ttttggaaag tataattata tcaaaatatg
    19741 tgattatgta tagatacaat ccactatgga gaaatataaa agaaaagagt ataacaaaca
    19801 ataaaaaata agatgattca aattttattt tgaaacatct tatttactct acaaattaag
    19861 attatttggt gaattattta attattattt tttattaaag aaattttaaa tcttaatata
    19921 aaatacgcta ttatacataa taatccaaat gcaaatgcta ctggaattaa catctccgat
    19981 tcaaaataaa agaaatattc taagaaaata tctggattta ctatattccc attcttgtct
    20041 aaaaaatctt ttccattata tcctaaatgc tgtataaaat tacttatgtt attataatct
    20101 gcttccctct catataccat attagcattc aatccagaag aacttaaatt agtgtttcca
    20161 tctttcatat ctattacata tagtctaaga gctttgactt tactatactt atctttatca
    20221 agtatttttt caagttctaa cttatattca ccaatctttg tcatatcatg tctttctgcc
    20281 aattgcttta tttctccatc aagttctttt cctaaattat acatattatg ttgtaaacta
    20341 ttattgtaat accacataaa tccagaaatt aaaaatgcaa ttatacttat gtaacctaat
    20401 acttttttaa accccattac aattgattta tgcctatcca atgataaaga tagttctttt
    20461 attatattac ataattcata ctgcatttca tcaccatcat caaatctttc aattgctttt
    20521 ttacatgctt cttcttcatc taatccttct aatttaaatt catttgcaga ttctataaga
    20581 tggcatctca tttcctgttt taattctata gtacttttat tgtcacattt tttatatagt
    20641 ttatctaaat attcatctat tagtttcata aattaatcca cctctcccaa aaattgattc
    20701 ataacctttt taataaatct ccattcttgt ttctttattt ctaaaaaatc tttaccttca
    20761 ttagttaaat tataatattt tcttcttcca cctgaacttt gttcattgct ataataagat
    20821 ttaattaaat ttttagattc cattctttta agtgcaagat acattgttcc ttcttttaat
    20881 tcaaactcac ttctttctct tacttgcttt gcaatttcat atccataaca atctttcttt
    20941 tctaatatag aaacaattaa tatatcgata taacctttta acacttcttt atttaactgc
    21001 attatgtacc accgcctttt cacctactac tctataatgt atagtactta tatttactat
    21061 aatattacat agtactctat attgc
//
LOCUS       DAEPKC010000070        21078 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.070, whole genome shotgun sequence.
ACCESSION   DAEPKC010000070 DAEPKC010000000
VERSION     DAEPKC010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21078)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21078)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21078
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.070"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(467..1339)
                     /locus_tag="KR294_002591"
     CDS             complement(467..1339)
                     /locus_tag="KR294_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBH0240656.1"
                     /translation="MEETNEMKDSKHLISNIQSQYTRLSKGQKLIAQYILNNYDKVAF
                     MTACKLGETVGVSESTVVRFANALGYSGYPKLQAALQELIKNKLTTVQRVEMAHDYSD
                     DFAILNKVLKSDIDNIRSTLEEIDERAFKEASNKLLRARKIYILGMRSSFVVAQYLGF
                     YLDIILDNVHIIRMDMGDAFEQIVRINEEDVIVAISFPRYSKKSYQIVNYAKEKGAHV
                     ISLTDSLFAPVASLADNTLLVKSNMASFVDSLVPALSISNALAISVGMKEKEDIKQHF
                     DDLEQIWKRYSVYE"
     gene            complement(1733..2311)
                     /locus_tag="KR294_002592"
     CDS             complement(1733..2311)
                     /locus_tag="KR294_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBH0240657.1"
                     /translation="MAYAKYLTKITDINKFYLENIINEGDIVIDATMGNGYDTRYLAE
                     KVGEKGFVYAFDIQEEAIKSTRKKLEKEGYTDRVKLIFDGHEKMNQYIKEEVSCVLFN
                     LGYLPRAKHSIITKPDTTLKAIKLSLEMLKENGVISIAIYTGHDGGQEEKDCIYNLVN
                     NLNQDEFNVLESKFLNQVNNPPQLILIEKKKA"
     gene            complement(2369..3085)
                     /locus_tag="KR294_002593"
     CDS             complement(2369..3085)
                     /locus_tag="KR294_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HBH0240658.1"
                     /translation="MRINKYIASCGIASRRKAEEIILGGRIKVNGSVVKELSFNIDEE
                     KDIVEFDNKKVKPSENYIYIVLNKPEGYITTVKDQFNRPSVIDILKDVRERVYPIGRL
                     DYETSGLLILTNDGDLTYKLTHPKHEIDKMYVASVKGIISDDEIRQFETGLKIEDYTT
                     APAKIRVTKENKEKNYSVCEITIHEGRNRQVRKMCKAINHPVLNLRRISVGKIVLKDT
                     KVGEYRYLTEDEIKYLKSIK"
     gene            3276..4361
                     /locus_tag="KR294_002594"
     CDS             3276..4361
                     /locus_tag="KR294_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBH0240659.1"
                     /translation="MIIISKENIKYYLIVVFIGILFFKFINTPSDFISSIEGFLKFFS
                     PFLLAILLALLLNPLVMLFEIKFKAHRLLAIFLSYIFIGFILAFAIRLLIPSIANTLN
                     RLINEMPMYTDYIDSFIEKNMSNIYFLKTLIPHIQHSLDNLLKEASNFVGKIPKNFLI
                     YTLSISSMLFNMTMGFILSIYIIYDKEKIALGFKRFLYSSTARNKADNIIEFFRTTHD
                     IFYDYLLGRILDSLIIGIIAFLGFQFVIRIENALFLASIIFLGNIIPYFGPFIGAIPP
                     IAMTILYSPQKTIWVIAFLFILQQLDGNFIEPKVMGNQVGIGAIWVISAILVGQSLFG
                     FIGVFLSVPIAAVVKTYVDKYIDNRLQ"
     gene            complement(4516..5175)
                     /locus_tag="KR294_002595"
     CDS             complement(4516..5175)
                     /locus_tag="KR294_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240660.1"
                     /translation="MRGRVILLISILSIFLVGCSFNKKDEINLVEQGKTYLEKHNYKK
                     AMESLSSALEEDSTNENARAMYMQAMRMSNMTEFEELKNYEGAIKELKLIEKIKNGSS
                     VIKEEATKKKEELTKLEKEQNEAEEQRKKKAKDTAGEDRYRVESDARKSSYSGSSKNN
                     KSSSKNNDKKSDSNKSDNSNSSSQNQEKPNNSNPTPAPTPQDTTGGSDSGGNSQNSNN
                     Q"
     gene            complement(5392..6684)
                     /gene="lysA"
                     /locus_tag="KR294_002596"
     CDS             complement(5392..6684)
                     /gene="lysA"
                     /locus_tag="KR294_002596"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HBH0240661.1"
                     /translation="MKLHGTMTVNNDELYIGGVSCLELSKKYQTPLYVFDEALVRQNC
                     REYVEYFKAREGKNKVAYAGKAFLPLYMCNLINEEQMCLDVVSGGELYTAYKSNFPME
                     KVFFHGNNKTKEEINMGLDLGVGKFVVDNFYELDLLEALCEDKGKTQEIYFRITPGIE
                     AHTHDYIKTGQIDSKFGFALVNGDLFRAIEKLSEYKNIKLVGLHAHIGSQIFDVEPYI
                     DTVDIMMNLVKEIKEKFNIQLTEIDLGGGVGVYYSEGDKPKTIKEFCETIITKAETSC
                     KELGIEVPTLVIEPGRSIVANAGSTLYTVGSIKDIKDVRVYVSVDGGMTDNVRPSLYQ
                     ASYECSIVNKINHEAMNHVTIAGKCCESGDILIGDINIMDIKSGDILITTSTGAYGYS
                     MSSNYNKIPRAAVVSVFDGNDKIICKRQSYEDLLALEI"
     gene            complement(6702..7895)
                     /locus_tag="KR294_002597"
     CDS             complement(6702..7895)
                     /locus_tag="KR294_002597"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HBH0240662.1"
                     /translation="MSIIVQKYGGSSVADTEKIKSIAENIIERRKENPQMVIVVSAMG
                     KSTDEYITLAKELSNEPSKRELDALMSTGEMISASLLSIALNALGCKAISYNAYQLNI
                     KTSGLHGKSQIDDINVNRIKNSLDEGNVVIVTGFQGINEDGDVTTLGRGGSDTSAVAL
                     AVKLNGKCEIYTDVDGIYFTDPRKYSKASKLDEIEYEEMLELASLGAQVMHSRSIELA
                     QKYGVEIYVGRTCGTEKGTYIRGGKDMKLEDKVITGLATSDDDSSITIKDFKAENISS
                     LFEDIATIGISVDMISQTAPILDKISVSFTVPKEELGECKKIVSKYTDEEHVVIDNNI
                     TKFSLVGLGMKNTSGVAAKVFKIFNENGIMIKLITTSEIRITCAINSDDKQVAIEKIA
                     EVFNI"
     gene            complement(8256..8873)
                     /locus_tag="KR294_002598"
     CDS             complement(8256..8873)
                     /locus_tag="KR294_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240663.1"
                     /translation="MTNMEKEILLLISRVRCVTESQFRKIYGDQKRYNKKNFKKTLRK
                     MCSEYTLKKYPCDVDYYNYKDLSYVYYLNGSKLFKGDDLIKALVGSELVVRINTAGCD
                     VKRFYRNVSVDDVKYDLFIEYTDQFGNIKQVLVDVDLNNEIDISKYENLSKKIDKSTI
                     PFFKVPNVLVVTPDNLSELNDLERYDNEYSINFIDLGLNKLFNCI"
     gene            complement(9043..10743)
                     /locus_tag="KR294_002599"
     CDS             complement(9043..10743)
                     /locus_tag="KR294_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240664.1"
                     /translation="MKRYLKTYGVALIIVIIYAFIKLPVLRLDFTSLFSVGIIFFVVA
                     GILDMMLDRNERASKMAKYNFSIAIALLVYIVVVPFITSTPVLHAKSYRELLGKVTES
                     KFTDDISPVSVNDIRLVDEDMAMKLGDKKLGEVPAIGSVSKLGKFHIQNVDGELYWVA
                     PLVHRDIIKWITSLSGTSGYVKVSASNPQDVQLVQEIDGKPIKIVYQPEAYLHQDLQR
                     HLYIHGIVNVGMTDFTLEINDEGRPYWVVSLYEHKIGYGGANATGIATVDAETGKINV
                     YDVKNTPKWVDRIQPQSFVTDQIKDWGVYVNGFLNSVISEKGVLVPTEGTSLVYGNDN
                     RSYWYTGITSSGGDESTIGFMLVDSRTKEARLYKQPGATETAAMKSAEGNVQEKNYEA
                     TFPVMYNILGQPTYVSSLKDKAGLVKRVAFVSVEDYNVLGIGEDKNEALRNYKDALES
                     KGNDLKLDNDLKDEVLEGTVTRISPDVRGGNTNYYVTLDSNKDIIFRATSKVSSELPL
                     TQVGDKVKISYSKEESGVIEMSEFDNLNIANFEDKKAKEKTGTDENTDSKDSENQGNV
                     "
     gene            complement(11140..11703)
                     /locus_tag="KR294_002600"
     CDS             complement(11140..11703)
                     /locus_tag="KR294_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240665.1"
                     /translation="MNKVYIVTTYTGTILSYLIRNISKKLYTHVSISLNENLKPMYSF
                     GRLNPRNPFIGGFVEENINQGLYAIRKNTVCRVYSLEVDNLQYENLYKNIKLISDYRE
                     DYYYDTMALIYLLMNIQRQSEYKYVCSNFVADMLEKSEIDILNKQAFEVTPNDFYNLS
                     GLTLEYEGLLSEYNSRQHSYVSKIANI"
     gene            complement(11862..12575)
                     /locus_tag="KR294_002601"
     CDS             complement(11862..12575)
                     /locus_tag="KR294_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2140 domain-containing protein"
                     /protein_id="HBH0240666.1"
                     /translation="MGKVAKILLSLIVIVLVLVGIVVYILTPKERYDVSSQNNKIIDE
                     EYLSKGSYINSMEVVKNPLRMVGKISVSEEEFKNLIYTLMQKHGINELENNFVEMKNG
                     KIKVAGPYKVFGLVNSQYELELRPTLKDGNLVVSLENVKIGKFKLSDKMLEKILSNYN
                     KKVPFEVNGNKITLEKSYLYPITLKNISIKKGNVDLDMEVEIDLKSQINGALGYLKDS
                     GKVQDILNHLINLKKTSVG"
     gene            12867..14531
                     /locus_tag="KR294_002602"
     CDS             12867..14531
                     /locus_tag="KR294_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--tRNA ligase/YqeY domain fusion
                     protein"
                     /protein_id="HBH0240667.1"
                     /translation="MSNETNSSNFIKNIIINDLETGKHDSIITRFPPEPNGYLHIGHA
                     KSICLNFGLAKEFNGKANLRFDDTNPLKEDVEYVESIKEDVKWLGFDWNELNFASNYF
                     DEMYKRALILIKKGKAYVCDLTQEEMREYRGTLTEPGKESPHRNRTIEENLDLFERMK
                     NGEFKDGEKTLRAKIDMSSPNINLRDPIIYRISHSTHHNTGDKWCIYPMYAFAHPIED
                     AIEGITHSICTLEFEDQRPLYDWFVKECEMENIPRQIEFARLNINNTVMSKRKLKQLV
                     DEGIVDGWDDPRVPTISGIRRKGYTAEALRNFCSEIGVSKVNSTVDSQMLDYFLRENL
                     QPKAPLTMGVLRPLKLIITNYPEDKIEMLEIENNAKDESQGKRLVPFSRELYIEQDDF
                     MEEPVKKYFRFFPGNEVRLKGAYFVKCTDVIKDENGNVVEIHGTYDPETKSGSGFTGR
                     KVKSTIHWVDAKSAIPCEFRLFEPLILDDIPENEGKHFLEQINPNSLEILQGFVEPTQ
                     IKDAKPFDKFQFVRNGFFSIDNKYTTDEKFVFNRIVPLKSSFKPGK"
     gene            complement(14638..15537)
                     /locus_tag="KR294_002603"
     CDS             complement(14638..15537)
                     /locus_tag="KR294_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegS/Rv2252/BmrU family lipid kinase"
                     /protein_id="HBH0240668.1"
                     /translation="MKKVKLIYNPNSGEKKILSNLDTIIELYQEKNYLLIPYRLTIKE
                     PVKNAFKEVDSSYEHILIAGGDGTVDLVVNAMKELDIKIPIGILPTGTANDFSNALQI
                     SFDIKEAINEIINSKPKKIDIGKVNNKYFINVASAGMFTDVSQRINTDLKNSFGRISY
                     YIKGIEEALYMRKFKIKVSSEEMYYDGDMYLMLIFNGKTAGNINLAYKAEIDDGYLDV
                     IIFKGMPIPKSIPVLISVLRGDYLDQYNGNEILYFKTKKVHIECEDSLITDIDGEKGP
                     DFPLNIECIKDGIEVMGICSEKS"
     gene            complement(15564..16202)
                     /locus_tag="KR294_002604"
     CDS             complement(15564..16202)
                     /locus_tag="KR294_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003356606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate utilization protein"
                     /protein_id="HBH0240669.1"
                     /translation="MDQNLNWLNEKRIEKTIKSLENNNMKGYLVSNKEELLKKIEEIV
                     KAGSLVGCGGSMTLFETGVIDFIREKYNFLDRYAKDIKPEEMKEIYRKSFSADAYFTS
                     TNAITEDGELYNLDGNGNRVAAMIYGPDKVIVIAGVNKIVKDVDEAIKRTKTIAAPAN
                     CKRLSTNTGCKTTGICIDCSSPGRICCSYTLIKRQLTPERIHVIFLNEDFGY"
     gene            complement(16539..17537)
                     /locus_tag="KR294_002605"
     CDS             complement(16539..17537)
                     /locus_tag="KR294_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4003 domain-containing protein"
                     /protein_id="HBH0240670.1"
                     /translation="MEQSFINGKVNLLIENYKALNEVKGSWQMGLIQHSCALAFTLKN
                     KKISPRLVEERIELIKKNTGLFSNFRGYNMFYMATLLSFESNPESSFKMILDIYKELK
                     SEKFWGDTYLPLTASIVYENREKMDYLTCISKMKIIYDYMRKKHPFLTSSDDYCNIAL
                     IAIHSKNLDEDLEYIEKCYEFLNENGFYKGNDLQALSQILLFSDDRTMLKCKKTIELK
                     KAFKENDCKMNYYGYPIIGAISLLDYREDEIIEEIKNVSNKLKEEKGFGNWSLGKSNR
                     VMISSAIVASIYADLIRNENNIGSITNNIFLNIVVAIQIACVMAATSAAIASSSSN"
     gene            complement(17635..18210)
                     /locus_tag="KR294_002606"
     CDS             complement(17635..18210)
                     /locus_tag="KR294_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240671.1"
                     /translation="MKLKEALITCVVCSVCLTPLLVNGETKIDADHCKESIVNIDTIV
                     KSGKSFNSKYNQGMEDYKNSDEYKLKVQKEKLQNQLGIKIKKLVPITFEVSYYTSLNQ
                     ENGYGAITATGDDLEDGFVANNHLSFGTKIIVDGKLKTVMDRGSSKYFSNSNAIDVFV
                     PKWSNESESEYYDRVNNMGRHYKKGYIIVEE"
     gene            18526..18789
                     /locus_tag="KR294_002607"
     CDS             18526..18789
                     /locus_tag="KR294_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240672.1"
                     /translation="MIKNTKQITVEVNEILLQEMSKITNYENNILTDLINESIVNYIL
                     ENKKHNIENKDLEEVIKFYKKENTEKPKSAARAIAEAKTHTLY"
     gene            complement(19226..19603)
                     /locus_tag="KR294_002608"
     CDS             complement(19226..19603)
                     /locus_tag="KR294_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBH0240673.1"
                     /translation="MTITKIPPAELKVMKFIWSSDFTVASKDVIEAMEKLYNWKQTTT
                     LTLLSRLVNKQFLSARKIDRHTHYTVLIGEEEYLHFETKTFLDNMHGSSIESFMKSLF
                     KKGVNEEELNSVEKWVKDIKKDE"
     gene            19944..21056
                     /locus_tag="KR294_002609"
     CDS             19944..21056
                     /locus_tag="KR294_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBH0240674.1"
                     /translation="MNAFIRKRNKNYVVYLEFEDEKTGKRKQKNMGTFDKKREASKRL
                     NEVKESLYNDGFLVPSEITVSEFLLDFLNKYSENISLATYNNYVSICKNYINPSIGKY
                     KIQDLHPVHIQNYIDKLSYKLNPQSIKIHINILKLAIKRAYRLKLIKENVMDSIEAPR
                     YKKFKNEIYDREQMIKLLDLAKNTEMELPINLAIGLGLRISEVLGLTWDNIDFEENTI
                     TVNKITSRINGSVILKEPKTESSVRKISSPKELMSLLKEYKIKQNKNLLKSSIRNNNN
                     LLFFNKKCEPIAEDVMSKKFKRFLEKNELPHIRFHDLRHSHVTLLINSKVPIKVISER
                     VGHSNISTTLSVYSHVLKEMDKEASDKISESLFNAN"
BASE COUNT         7086 a         3367 c         2227 g         8398 t
ORIGIN      
        1 ttctaaaaaa gtttcccttt ccccaaaaat ggctacttaa aaaatcaaga tttcatacct
       61 aactactaat tctatgattt ttaaattttt caacttcttt gtcaaagtta aaataaaata
      121 ctaaaagaca catattatag tgaacaaaaa agatagaaat acatatttta atagaatttt
      181 aataagatat tatatactta aatacaaata aaattaattt tataattgtt aattaaggaa
      241 atgatattgt ttagagaaat aaaaaaagca ctctccatga agggaaatgc tttctttaat
      301 aaattagttg atgtagtaaa gatatattca gaatacatct ttatgttttg agtctcgaaa
      361 tatttatttg tattatttaa acgaaaattt attttttaag tgataatcta gtatttatta
      421 ataaggctat gattctcaat ttcatagcct tattaataca caaactttac tcatacacag
      481 aatatctttt ccaaatttgc tctaaatcat caaaatgctg tttaatatct tctttttcct
      541 tcatcccaac agatatagca agagcatttg aaatactaag agctggaact agagaatcta
      601 caaatgaagc catattactc ttaactagaa gagtgttatc tgcaagtgat gctactggcg
      661 caaataagct atctgttaat gatattacat gggctccttt ttctttagca taattgacaa
      721 tttgataaga tttcttagaa taacgaggga aactaatagc aactattaca tcttcttcat
      781 ttattcttac aatctgctca aaagcatctc ccatatccat tctaattata tgaacattgt
      841 caagtattat atctaagtaa aaacctaaat attgagctac tacaaaagaa ctcctcattc
      901 caagtatata tatttttctc gctcttaaaa gtttgttaga agcttcttta aacgctctct
      961 cgtcaatttc ttctagtgta gaccttatat tatctatatc actttttaaa actttgttta
     1021 gtattgcaaa atcatcggaa taatcatgtg ccatttcaac tctttgtact gtagttagtt
     1081 tattttttat gagttcttga agtgcagctt gtaatttagg atatccacta taacctaatg
     1141 catttgcaaa tcttacaact gtagactcac ttactcctac agtttcaccc aatttacatg
     1201 cagtcataaa tgcaacttta tcataattat ttaaaatgta ttgtgctata agtttttgac
     1261 ccttactcaa tctcgtatat tgagattgta tatttgatat caaatgttta ctgtccttca
     1321 tttcatttgt ttcttccatt tttttctcct tttagttata taaactattt tgttttatta
     1381 acactgtctt tttctctaaa aattttattt tttatctcaa tttcatctta gtttttatca
     1441 tagcttctta aactcataaa attctaactt ttctgtacct tatacttcac atagtatttt
     1501 cgattaaatt tattatacca tctttccttg cattttttaa tatttatcca atatttcttt
     1561 taaatttttc aatttttact catttaaaag ttatctatct tattttgcat atttagatgt
     1621 atattttgtt ttgagaataa actgttgtat acttattatt taaagtattt ttaataggtc
     1681 acactatata tattaactct taatacaatc ttgtcaagtt ttttagtatt tattatgctt
     1741 ttttcttttc aattaaaatc aattgtggtg ggttattgac ttgatttaaa aacttagatt
     1801 ctaaaacatt aaattcatct tgatttaaat tattgacaag gttatatatg caatcttttt
     1861 cttcttgacc tccatcatgc cctgtatata tggcaatgct tattactcca ttttctttta
     1921 acatttctaa acttaacttt atagccttta aagttgtatc tggtttggtt ataattgaat
     1981 gtttcgctct tggaagataa cccaaattaa ataaaacaca tgaaacttct tcttttatat
     2041 attgattcat tttttcatgc ccatcaaata tcaattttac tctatctgta tatccttctt
     2101 tctctagttt ctttcttgta gactttattg cttcttcttg tatatcaaaa gcatatacaa
     2161 agcccttttc tccaaccttc tcagctagat accttgtatc atacccattt cccatagtag
     2221 catcaattac tatgtcacct tcatttataa tattttctaa ataaaattta tttatatctg
     2281 taattttagt taaatacttt gcatatgcca taatactatt tctccctact attaacttta
     2341 tttcattttt tctcaattta tttttatctt attttattga ttttaaatat tttatttcat
     2401 cttctgttag gtatctatat tctccaactt tggtgtcttt taatactatt ttccccacag
     2461 aaatccttct taaatttaaa actggatgat ttatagcttt gcacattttt cttacttgtc
     2521 tatttctacc ctcatgtata gttatttcac acactgaata atttttttct ttattttctt
     2581 tagttaccct tattttggca ggtgccgttg tgtaatcttc tatttttagt cctgtttcga
     2641 attgtcttat ctcatcatca cttataattc ccttcacact tgccacatac attttatcaa
     2701 tttcatgctt tggatgggta agcttatatg ttaaatcgcc atcattagta agtattaata
     2761 aaccactagt ttcataatct aatctcccta ttggatatac tctttccctt acatctttaa
     2821 gtatgtctat tacactgggt ctattgaatt ggtcttttac tgtagttata tatccctctg
     2881 gtttatttaa tactatatat atataatttt cacttggttt tactttttta ttatcaaatt
     2941 ctactatgtc tttttcttca tcaatattaa aagataactc ttttactaca cttccattta
     3001 cctttattct tcctccaaga attatttctt ctgcttttct tcttgatgct attccacaag
     3061 aagctatata cttattaatt ctcatactta atccttcctt atcttaaatt atgtgtgttt
     3121 aatattttta tcaatgttaa ttttgctaca ttattatact atactagacc ttaattaaaa
     3181 acaagcaaaa aaattattta attttcctaa ataattgtaa tttcttttca catactatta
     3241 atatgtaata gctgactaaa cactatttta aggaagtgat tattatttca aaggaaaata
     3301 taaaatatta tttaatagtc gtgtttattg gaattttatt ttttaaattt attaatactc
     3361 catcagactt tatatctagt attgaaggat tcttaaagtt ttttagccca tttttattag
     3421 ctattttact tgctttactt ttaaatccac ttgtgatgct ttttgagata aaattcaaag
     3481 cacatagact tttagccatt tttttatctt atatatttat aggttttatt ttagcctttg
     3541 ccattaggtt attaattcca tcaatagcta atacattaaa tagattgata aatgaaatgc
     3601 ctatgtatac tgattatata gatagtttta tagaaaaaaa tatgtcaaac atatattttc
     3661 taaaaacttt aattcctcat atacaacata gtttagataa tttattaaaa gaagcaagta
     3721 attttgttgg taaaattcct aaaaacttct taatctatac acttagtata tcttctatgc
     3781 tatttaatat gacaatggga tttatactat ctatatacat tatatatgac aaagaaaaaa
     3841 ttgcattggg atttaagaga tttctatatt cttctactgc tagaaacaag gcagataaca
     3901 ttatagaatt ttttaggact actcatgata ttttctatga ttatttactt ggtagaatat
     3961 tagactctct tattattggt ataattgcat ttttaggatt tcaatttgtt atcagaatag
     4021 aaaatgcttt atttttagct tcaataatat tcttaggtaa tataattccc tattttggtc
     4081 cttttattgg tgcaatccct ccaatagcca tgactatatt atatagtcca caaaaaacta
     4141 tatgggtcat tgcatttcta tttatattgc aacaattaga tggaaatttt atagaaccaa
     4201 aagttatggg taatcaagtt ggtataggag ctatatgggt aatatctgct attttggtgg
     4261 gacaatctct atttggtttc ataggagttt ttctttcagt accaatagct gctgttgtaa
     4321 aaacttatgt tgataaatat atagataatc gtttacaata gcttatctct actgtgactt
     4381 taatttttag tttaaaattt aactgttatt tattaaatta tttctcaaaa aatatctctt
     4441 agtaagaaaa aattgctaag agatattttt tataatatat aatttgttca ttaaatttat
     4501 gcatatattt tatacttatt gattatttga gttttgagaa tttccaccac tatctgaacc
     4561 accagtagta tcttgtggag ttggtgctgg tgttggatta ctattatttg gcttttcttg
     4621 attttgagaa gaactgttac tattgtcaga cttattacta tctgattttt tatcattatt
     4681 tttagaacta gatttattat ttttactact tccactataa gaagatttcc ttgcatctga
     4741 ttcaactcta tacctatctt ctccagccgt atcttttgcc tttttctttc tttgttcctc
     4801 tgcttcgttt tgttcttttt ctaatttagt taactcttct ttctttttag ttgcctcttc
     4861 tttaataaca gaggaaccat ttttgatttt ctctataagt ttaagttcct tgattgcacc
     4921 ctcataattt tttaattctt caaactccgt catatttgac attctcatag cttgcatata
     4981 catagctctt gcattctcat tagtactatc ttcttccagt gcagaggata atgattccat
     5041 agctttttta tagttatgtt tttctaaata tgtttttcct tgctctacta aatttatttc
     5101 atctttttta ttaaatgaac atcctacaag aaatatagat aatatcgata ttaataaaat
     5161 tactcttcct ctcattaaat ccctccttgt catatacttt aaattttatc ataattataa
     5221 agtttttaaa atattttata tttattacaa gaaatttgtt agtaaaacaa aaaataagca
     5281 gatatgctac gaacgataca ataaaccaaa aattaattta gagatacata tcctagcaaa
     5341 tctgctcata ataaacttta atatttaatt tttattatat acttctccat tttatatctc
     5401 taaagctaat aagtcctcat agctttgtct cttacaaatt atcttatcat ttccatcaaa
     5461 tactgatact actgctgctc ttggtatttt attataattt gaagacattg aatatccata
     5521 tgcaccagtt gatgttgtta taagtatatc tccactttta atatccatta tgtttatatc
     5581 tccaattaat atatctccac tctcacaaca ttttccagct attgttacat gattcatagc
     5641 ctcatgatta attttattca caatactaca ctcataacta gcttggtaca acgaaggtct
     5701 tacattatct gtcatacctc catctacact tacataaacc ctaacatctt ttatatcttt
     5761 tatagaacct actgtataca atgtacttcc tgcatttgca actattgacc ttcctggttc
     5821 tattaccaat gtaggtactt ctattccaag ctctttacat gaagtttctg ctttagtgat
     5881 tatggtttca caaaactctt ttatagtttt aggtttatct ccttcgctat aataaacgcc
     5941 aactcctcca cctaggtcaa tttctgttag ttgtatgttg aatttttctt ttatttcttt
     6001 taccaagttc atcattatat ccactgtatc tatgtatggt tctacatcaa atatttgtga
     6061 acctatatga gcgtgaagac ccacaagttt aatattttta tattcactta atttttctat
     6121 tgctctaaat aaatctccat ttactaaagc aaatccaaat ttagaatcta tctgtccagt
     6181 ttttatataa tcatgtgtat gagcttctat accaggagtt attctaaagt atatctcttg
     6241 agttttacct ttatcttcac ataatgcttc aagcaaatct aattcataaa aattatccac
     6301 cacaaattta cctacaccta aatctaatcc catgtttatt tcttctttag tcttattgtt
     6361 tccatgaaag aaaacttttt ccataggaaa atttgattta taagctgtat ataactcgcc
     6421 tcctgaaact acatctaaac acatttgttc ttcatttata agattacaca tgtaaagagg
     6481 taaaaaagct ttccctgcat aagcaacctt attttttccc tctctagcct taaaatattc
     6541 tacatattct ctacaatttt gtctaactaa agcttcatca aatacataaa gtggagtttg
     6601 atatttttta ctaagttcta aacaactcac tcctccaata tataattcat cattatttac
     6661 agtcatagtt ccatgaagtt tcataatagc ctccccaaat tttatatatt aaatacttct
     6721 gctatttttt ctatagctac ttgcttatca tcagaattta tagcacaagt tatacgaatc
     6781 tctgatgtag ttataagttt tatcattata ccattttcat tgaatatctt aaatacttta
     6841 gcagcaactc cagaagtatt tttcatacca agacctacta aagaaaattt agtgatatta
     6901 ttatcaatca ctacatgttc ttcatctgta tatttagata ctatcttttt acattctccc
     6961 aactcttctt ttggaactgt aaatgataca cttatcttat ctaaaatagg tgcagtttgg
     7021 cttatcatat ctacacttat acctatagtt gctatatctt caaataagct agatatattt
     7081 tcagctttaa aatcttttat tgttatagaa ctgtcatcat cactagtagc taatcctgtt
     7141 attactttat cctctaattt catgtctttt ccccctctta tatatgttcc tttttctgta
     7201 ccacatgtac gtccgacata gatttcaaca ccatattttt gtgcaagctc tatacttctt
     7261 gaatgcatta cttgtgctcc taaactcgct aactcaagca tttcttcata ttcaatctca
     7321 tcaagtttac tagcctttga atattttctt gggtctgtaa aataaattcc atcaacatct
     7381 gtatatatct cacattttcc atttaattta accgcaagag ctacagcaga tgtatctgaa
     7441 ccacctcttc caagagtggt tacatcacca tcttcgttga ttccctgaaa tccagttact
     7501 atcacgacat ttccttcatc taaactattt ttaattctgt ttacgtttat atcatcaatt
     7561 tgagactttc catgaagacc actcgttttt atatttaact ggtaagcatt ataacttata
     7621 gctttacatc caagtgcatt taatgctatt gataataaag atgctgaaat catttcacca
     7681 gtagacatta aagcatctaa ttccctctta ctaggttcat tactcaattc ctttgctaaa
     7741 gttatatatt catcagtgga ttttcccatg gcagacacaa ctattaccat ttgtggattt
     7801 tcttttcttc gttctattat attttctgct attgatttta ttttttcagt atctgctact
     7861 gaacttccac catatttttg aacaattata ctcatgcttt ctccccctca agctaaattt
     7921 tgataaataa aaacgcccaa aggtatactt tggacgtgta aatttcatag accaagtaac
     7981 cttgtagctc accactttaa aagtgacagc cttatgcata ttctgcataa gtccagaaaa
     8041 tttgtccgtc aacaaaattt cttcggctat ataccctttc atcaattatc aacgcttacc
     8101 agctcctatt gaatactatt gaatacagct acctctaccc taggctcatt atttttaatt
     8161 aatttattaa tatagtttta tcatattcta tataatattg caacaattat tttacaaaat
     8221 gtggcaaatc gatagttttc ttttctaaag ttagcttata tacaattaaa tagtttattt
     8281 aatcctaaat ctataaaatt tatgctatac tcattatcat atctctctaa atcatttaat
     8341 tcggatagat tatctggtgt aactaccaaa acgtttggta ctttaaaaaa tggaattgta
     8401 gatttatcta tttttttaga aagattttcg tatttagaaa tgtctatttc attatttaag
     8461 tcaacatcaa ctaaaacttg ctttatatta ccaaattggt ctgtatattc aataaataaa
     8521 tcgtatttca catcatctac actaacattt cggtaaaatc tttttacatc acaacctgca
     8581 gtattgattc taacaactaa ttctgatcct actagagcct ttattaaatc atctccctta
     8641 aaaagtttac taccgtttaa atagtataca taagagaggt ctttataatt ataataatcc
     8701 acatcacaag gatatttttt tagtgtatat tcactacaca tttttctcaa agttttttta
     8761 aaattttttt tattgtatct tttttggtct ccataaattt ttctaaattg agactctgta
     8821 acacatctaa ccctgctaat taaaagtaat atctcttttt ccatattcgt catagtacat
     8881 tctccttgaa gtattatttg caaagttgta ctaatattat attaatttta tgacattaaa
     8941 tttacaaaga attaaaataa aatagctaat ttttatagaa ttaaattcta taaaaattag
     9001 ctatcactat gttaaatact attatcaatc tttttattta aattatacat taccttgatt
     9061 ttcagaatct ttggaatctg tattttcatc agttcctgtt ttttcttttg cttttttatc
     9121 ttcaaagttt gcaatattta ggttatcaaa ttctgacatt tctattacac cagattcttc
     9181 ttttgaatac gatattttga ctttatcacc aacctgagtc aatggcaatt cgctagatac
     9241 ttttgaagta gccctaaata ttatatcttt atttgaatct aaagttacat aataattagt
     9301 gttaccacct cgcacatctg ggcttattct tgtcactgtg ccttctaata cctcatcttt
     9361 taaatcatta tcaagtttta aatcattacc cttagattct aatgcatcct tatagtttct
     9421 taatgcttca ttcttatctt cacctattcc aagtacatta taatcttcaa cagatacaaa
     9481 tgcaactctc ttaacaagac cagccttatc ttttaatgat gatacatatg ttggctgacc
     9541 caatatatta tacattacag ggaacgtcgc ttcataattt ttttcttgaa cattaccttc
     9601 agctgatttc attgcagccg tttcagtagc tcctggttgt ttatataatc tagcttcttt
     9661 tgttctagaa tcaactaaca taaatccaat tgtagattca tctccacctg aagatgttat
     9721 acctgtatac caataagacc tgttatcatt gccataaact agtgatgtac cttctgttgg
     9781 tactaaaact cccttttctg atataacaga gtttaaaaat ccattaacat aaacacccca
     9841 gtctttaatt tggtctgtta caaagctttg tggttgtatt ctatccaccc atttaggcgt
     9901 gtttttaaca tcataaacat ttatttttcc agtttctgca tcaacagtgg ctattcctgt
     9961 tgcatttgct cctccatagc caattttatg ttcatataaa cttacaaccc aataaggtct
    10021 tccttcatca tttatttcaa gagtgaaatc tgtcatacca acatttacaa taccatgtat
    10081 gtataaatgt ctttgtaaat cctgatgtaa gtaggcttct ggttggtaaa ctatctttat
    10141 tggctttcca tctatttctt gaactaattg gacgtcttga ggattactag ctgatacttt
    10201 tacataacca cttgtaccac ttagagatgt tatccattta attatgtctc tgtgaacaag
    10261 aggcgctacc cagtacaact ctccatctac attttgtata tgaaattttc ctaatttgga
    10321 tacactccct attgcaggaa cttctccaag ctttttgtca cctaatttca ttgccatatc
    10381 ttcatctaca agacgaatgt catttacact gacagggcta atgtcatcag taaatttact
    10441 ttcagttact tttcccaata gttctctata tgattttgca tgaagtacag gtgtagaagt
    10501 tataaaggga actactacaa tatacacaag caaagctatt gctattgaaa aattatattt
    10561 agccatttta gatgctcttt catttctatc taacatcata tctagtattc ctgctacaac
    10621 aaagaaaatt attcctactg aaaataaaga tgtaaaatct aatcttagta caggtaattt
    10681 aataaatgca taaattatta caattattaa tgcaactcca tatgttttaa gatatcgttt
    10741 catttaatac tcctctctaa aaaatgttat tattactatt atatccatat atttacaaaa
    10801 aataaatatt tatcatattt attatatatt aagatatctt tatatattta tagttctgct
    10861 tattcaacta tatttaacat tatacgtgta tgtataaata ctttttatac actgtttgta
    10921 ctatccatcc cgcacctaaa ggagtgggat ttttgcacta ttctgtatta tatatatcca
    10981 aaaatattat aaaaatacaa atattagcag aaatttaaaa actgaagaaa gtattctaac
    11041 taagatttac aaattcttaa tcctatcgaa gttaaactac tatcttcagc ctaattatct
    11101 agcaatattt ttttatatga aaaactctaa atcaagtttt taaatgtttg cgatttttga
    11161 tacataagaa tgttgtctag aattatattc tgataataaa ccttcatact ctaaggttaa
    11221 gccagataaa ttataaaaat catttggcgt tacttcaaat gcttgtttat ttaaaatgtc
    11281 tatctcactt ttttctaaca tgtcagcaac aaaatttgaa catacatatt tatattcaga
    11341 ttgtctctga atattcatta gtaaatatat taatgccatt gtatcgtaat agtaatcttc
    11401 tctataatca ctaattaatt ttatattttt atatagattt tcatattgta aattatctac
    11461 ttctaacgaa tataccctac acacagtgtt ttttcttata gcatataatc cttgatttat
    11521 attttcttca acaaatcctc caataaatgg attccttgga tttagccttc caaaagaata
    11581 cattggtttt agattttcat ttaatgatat tgacacatgt gtatacagct ttttacttat
    11641 attccttatt aagtaagata atatagttcc tgtatatgtt gttacaatat agactttatt
    11701 catcatttcc ccccaatcta gtaactaaat aatattatac acttacaatt taatatcata
    11761 agatattcta acataataaa tgtggtttta caaattttga ttttaaggta ctttaatatt
    11821 atataatata ataaaaatat aaatataagt tttctatatt tttaaccaac agatgttttc
    11881 ttcaaattaa tcagatgatt tagtatatct tgaacctttc cagagtcctt taaatatcct
    11941 aatgccccat ttatttgtga ttttaaatct atttctactt ccatatccaa atcaacattt
    12001 ccttttttta tagatatatt tttaagtgtt attggataaa gataactttt ttccaaagta
    12061 atcttatttc cattaacctc aaatggaact tttttattgt agttacttaa tattttttct
    12121 agcattttat cacttagttt aaattttcca attttcacat tctcaagact tacaactaag
    12181 tttccatcct ttaaagtagg tctcaattca agttcatatt gactatttac caaaccaaat
    12241 accttatatg gtcctgctac ctttatttta ccatttttca tttcaacaaa attattttca
    12301 agttcattaa ttccatgctt ctgcatcaat gtatatatta aatttttaaa ctcttcctct
    12361 gaaacagata tttttccaac cattctaagt ggatttttta ctacctccat agaatttata
    12421 tatgagcctt ttgataaata ttcttcatct atgattttat tattttgtga actaacatca
    12481 tatctttctt ttggtgtcaa gatatataca acaattccta caagtactaa aacaataaca
    12541 attaaactta acaaaatctt tgcaaccttt cccataatcg tctcctttac aaatctgtca
    12601 tcagatttaa aataaattta gataactaac ttcacataat attcttaaca atatacatac
    12661 tataatacag tcttttaaaa attaattcaa ccaatctaat gttttgtaaa taaactgtaa
    12721 aaacatgttt ttagtataaa agttaatatt ttgcataata ctcttaatta cacctttatt
    12781 tttttctaat cttggattaa aattaatatt atgcaataca gtgtagtgtt ctgtattata
    12841 atcaaattaa ataggaggta tagaatatgt caaatgaaac gaactcatct aactttataa
    12901 agaatattat tataaacgac ttagaaacag gaaaacatga cagtatcata actcgttttc
    12961 cacctgagcc aaacggatat ttacatattg gtcatgcaaa aagtatatgt cttaattttg
    13021 gattagctaa ggagtttaat ggaaaagcta atttaagatt tgatgataca aacccattaa
    13081 aagaggatgt tgaatatgta gagtccataa aagaagatgt aaagtggtta ggatttgatt
    13141 ggaacgagtt aaattttgca tctaactact ttgatgaaat gtataagaga gctttaatac
    13201 taataaaaaa gggtaaagct tatgtatgtg atttgacaca agaggaaatg agagaatatc
    13261 gtggtactct aactgaacca ggaaaagaaa gtcctcatag aaacagaact attgaagaaa
    13321 accttgattt atttgaaaga atgaaaaatg gtgaatttaa agatggtgaa aaaacattaa
    13381 gagccaaaat agatatgtct tctccaaata taaaccttag agacccaatt atatatagaa
    13441 tatctcattc aacacaccat aatacaggag ataaatggtg catatatcct atgtatgctt
    13501 ttgctcatcc aattgaagat gcaattgaag gaataactca ctctatatgt actttagagt
    13561 ttgaagacca aagacctctt tatgattggt ttgttaaaga atgtgagatg gaaaatatac
    13621 ctagacaaat agaatttgct agacttaata taaataatac tgtcatgagt aaaaggaaat
    13681 taaaacaact tgtagatgag ggtattgttg atggttggga tgaccctcgt gttcctacaa
    13741 tatccggaat cagacgtaag ggatatactg cagaagcatt gcgcaatttc tgtagtgaaa
    13801 taggggtatc aaaagttaac tctacggtag atagtcaaat gcttgattat ttcctaagag
    13861 aaaacttaca accaaaggct cctcttacta tgggagtttt aagaccttta aaacttatta
    13921 taactaatta cccagaagat aagattgaga tgcttgaaat agagaataat gctaaagatg
    13981 aatctcaagg aaagagatta gttcctttct ctagagaatt gtatatagaa caagatgatt
    14041 ttatggaaga acctgttaag aaatatttta gatttttccc aggaaatgaa gtccgtttaa
    14101 aaggtgctta ttttgtaaaa tgtactgatg taattaagga tgaaaatgga aatgtagttg
    14161 aaatacatgg tacttatgac cctgaaacta agagtggctc tggctttaca ggacgtaagg
    14221 taaaatctac aatacattgg gttgatgcta aatcagctat cccatgtgaa tttagattat
    14281 ttgaaccatt aattcttgat gatatacctg aaaatgaagg taaacatttc ttagaacaaa
    14341 taaatcctaa ttcattggaa atattacaag gttttgttga acctacacag ataaaagatg
    14401 ctaaaccttt tgataaattc caatttgtta gaaatggatt ctttagtata gataataaat
    14461 atacaactga tgaaaaattt gtatttaata gaatagttcc tctaaaaagt tcttttaaac
    14521 caggtaaata atcttacaat caaaaaatga agacttaaaa tataaattac ttctactata
    14581 aataaactta gttagaagta attttttatt tgagtcttca tcatttactt taaatgatta
    14641 acttttttca ctacagattc ccatgacttc tattccatct tttatgcatt ctatgttaag
    14701 aggaaaatct ggtccttttt ctccgtcaat atctgttata agtgaatctt cacattctat
    14761 atgcaccttt ttagttttaa agtatagtat ttcatttcca ttatattgat ctaaataatc
    14821 acctctaagc acacttatca aaactggtat tgattttggt attggcattc ctttaaaaat
    14881 aattacatcc aaatatccat catctatttc agccttatat gctagattta tatttcctgc
    14941 tgttttgcca ttaaaaatca acataagata catatctcca tcataataca tttcctcaga
    15001 agatactttt atcttaaatt tcctcatata caatgcttct tctattccct ttatataata
    15061 agaaattctt ccaaatgaat tttttaagtc tgtgtttatc ctttgtgata catccgtaaa
    15121 cataccagca cttgcaacat ttataaagta cttattattg actttcccta tgtctatttt
    15181 ctttggtttt gaatttatga tttcatttat agcttctttt atatcaaatg aaatttgaag
    15241 agcatttgaa aaatcatttg cagttcctgt aggcaaaatt ccaattggaa tttttatgtc
    15301 taattctttc attgcattta ctactaaatc tacagtacca tcaccaccag ctatcaatat
    15361 gtgttcataa gaactatcaa cttccttaaa tgcattcttt acaggttctt taatagttaa
    15421 tctatagggt atcaataaat aatttttttc ttgatataat tctatgatag tgtctaaatt
    15481 tgataatatc tttttttcac ctgaattagg attgtatata agttttactt ttttcattat
    15541 ttctccttac tcattttatt cttttagtat ccaaaatctt catttaaaaa aatcacatgt
    15601 attctttctg gtgttaattg tctttttata agtgtataac tacagcatat tcttcctgga
    15661 cttgaacagt ctatacatat accagtagtc ttacatccag tatttgtact taatctttta
    15721 caattggctg gagcagctat tgtttttgtt ctttttatag cttcatctac atctttaact
    15781 attttattta ctcctgctat aactattact ttatcaggtc catatatcat agcagcaact
    15841 ctattcccat tcccatctaa attgtaaagt tctccatcct ctgttatcgc attagtactt
    15901 gtaaaataag catctgcaga aaatgacttt ctatatattt ctttcatttc ttctggtttg
    15961 atatcttttg catatctatc aagaaaatta tatttttctc ttataaaatc aatcactcct
    16021 gtttcaaata aggtcataga acctccacat cctactagag aacctgcttt aactatttct
    16081 tcaatttttt taagaagctc ttctttgtta cttactaaat accctttcat attattgttt
    16141 tccaaagatt ttattgtttt ttctattctt ttttcattaa gccaatttaa attttgatcc
    16201 attttaactt cccccttatt tttaatatgt acttaattat ttataaactt tattttcttt
    16261 ataagtttat tttagtacat ctaaaaaaaa atacaatata aaacttaaat agttttacat
    16321 aattttttcc aaaataactt actcaatcaa aaaaggaaag tagatgtact attctacttt
    16381 ccctatattg tatgtagtat ttattgccta aaatctatat attaattata tgtttcatat
    16441 tatataatat cacagttaat taaaatgtaa tactatcttc tttttaaaca tataaattgt
    16501 attattaaat ttaatatatc caacttcaat aaatcttatt aatttgatga agaagatgct
    16561 atagctgcac ttgttgctgc cattacacat gcaatttgaa tagcaacaac aatatttaaa
    16621 aatatattat tagttataga gcctatatta ttctcatttc gtatcaaatc tgcataaatt
    16681 gaagctacaa tagcagaact aatcattact ctattacttt ttcctaaaga ccaatttcca
    16741 aagccttttt cttctttaag tttatttgaa acatttttta tctcttctat tatttcatct
    16801 tctctataat ctaataatga aattgctcct attattggat atccataata attcatttta
    16861 caatcatttt ctttaaatgc ttttttaagt tcaatagtct ttttacattt aagcatagtt
    16921 ctatcatcac taaataaaag aatttgggat aatgcttgta aatcatttcc tttataaaaa
    16981 ccattttcat ttagaaattc ataacatttt tctatgtatt ctaaatcttc atctaaattt
    17041 tttgaatgaa ttgcaataag tgctatatta caatagtcat cactagaagt tagaaatgga
    17101 tgttttttcc tcatgtaatc atatattatt ttcatttttg atatacatgt aagataatcc
    17161 attttctctc tattttcata aactattgat gctgtaagtg gtaaatatgt atcgccccaa
    17221 aacttttcac ttttaagttc tttgtatata tctaaaatca tcttaaaact actttctgga
    17281 tttgattcaa acgaaagtag tgttgccata taaaacatat tatatcctct aaaattagag
    17341 aataatccag tatttttttt aataagctct attcgttctt ccactaatct aggacttatt
    17401 ttcttgttct taagggtaaa tgcaagtgca caactatgtt gtatcaatcc catttgccaa
    17461 gaacctttaa cttcatttaa tgctttgtaa ttttctatta ataagtttac ttttccattt
    17521 ataaacgatt gttccatatt gccctcctag taatatatct cattgtacta atagttttat
    17581 atttattata tatatattaa atactacaat caatacatat tacttcaaag aacatcattc
    17641 ttcaacaata atgtagcctt ttttgtaatg tcttcccata ttattgactc tatcatagta
    17701 ctctgattca ctttcattac tccatttggg cacaaataca tctattgcat tagaattact
    17761 aaaatactta ctagaccccc tatccataac agtttttaat tttccatcta caataatctt
    17821 agttccaaaa cttaagtgat tgtttgctac aaaaccatct tctaaatcat ctcctgtagc
    17881 agttatcgct ccatatccat tttcttgatt aagacttgtg taataactaa cttcaaaagt
    17941 tataggtact aacttcttta ttttaatacc taactgattt tgtagtttct ccttttgtac
    18001 tttcaactta tactcatcac tatttttata atcttccata ccttgattat acttggaatt
    18061 aaagctttta cctgacttta ctatagtatc tatatttact atagattctt tacaatgatc
    18121 tgcatctatt tttgtttctc catttaccaa taatggagtt aaacatacac tacatacaac
    18181 acatgtaatc aatgcttctt taagcttcat aaattccccc cttattattt tgatatatta
    18241 gcatatttaa tattatatgt ctacatttag atttaaatac cacacccatt tgctttaaga
    18301 agttgtctta tatttaattc accttaaaca cttataaatc ctctatctta gaatcatata
    18361 gaataaagct tttatcatta aatatttttt attaatcttt taaaatctaa aactacttta
    18421 tctaattttc tcttttttag aatttaagaa ttaaaattct ataattttaa aacatattga
    18481 atttattttt ttgagatgat ataattttct taagaggtgg ttgatatgat aaaaaataca
    18541 aaacaaatta cagtagaagt taatgaaatt ttattacaag aaatgtctaa gataactaat
    18601 tacgaaaata atattttgac agatttgata aatgaatcaa ttgtaaatta tattcttgaa
    18661 aacaaaaaac ataatattga aaataaagat ttagaagaag tgattaaatt ttataaaaaa
    18721 gaaaatactg aaaaacctaa aagtgcagca agagctatag ctgaagcaaa aactcatact
    18781 ctgtattaat caaataaaaa agttcctaaa aactaggaac ttttttatat taataattat
    18841 taatatatct caatatttat ctcaaatcta tcaatataag catgtttaat acaatctatt
    18901 gtatacttat cttaccctag aaataatcaa aacaaaaata aaattatgcc ctttatatct
    18961 aaaacaatta atttacatga ttaatataca aaaattctga cttttaaatt cgtatacaat
    19021 atcaaactaa aataatatta atgacaaacc caatataaat taaattcaaa caggtttgat
    19081 tttacatcaa acttattgta ttaatattaa ataacaagac aaaaatattt ataaaaatca
    19141 caaattttac ataaaacttt atatttgatt catttaacta attattgtaa aaactattta
    19201 ttttatgata attaactaca ccaaattatt catctttttt aatatcttta acccattttt
    19261 caacagagtt caattcttct tcatttaccc cctttttgaa caaggatttc ataaaactct
    19321 caatagaact tccatgcata ttatctaaaa aagtttttgt ttcaaaatgt aaatactctt
    19381 cttctccaat aagaactgta taatgtgtat gtctatcaat ttttcttgca cttaagaatt
    19441 gcttatttac taatcttgat aaaagtgtta gtgttgtagt ttgcttccaa ttatatagtt
    19501 tttccatagc ttcaatgaca tcttttgatg ctactgtaaa atctgaactc caaataaatt
    19561 tcatgacttt taattctgct ggtggtatct tagtaatagt catatgattt tacactcctc
    19621 tcaaacttct acataattaa atactatatt aatagacttt tcgagtcaaa ggttttattt
    19681 aaaatatctc atccaaattt attaatacaa aaaatttata tttttattca aaattaaaca
    19741 cacaatctat taatataaag ataaatatct attctataag tataacagat tatcaaatta
    19801 aaattctaat atttgacata atatatacat tttttaaata aatatataca atgtattaaa
    19861 atgtatgcaa ctctatttca aaattatttt gtgatatata tatgttataa taaatgtata
    19921 aaattttgat tggtgggtta tatatgaatg catttattag aaaaagaaat aaaaactatg
    19981 ttgtttacct ggaatttgaa gatgaaaaaa caggtaaaag aaaacaaaaa aatatgggta
    20041 cttttgataa aaaaagggaa gcaagtaaaa gactaaatga ggtaaaagaa agcttatata
    20101 atgatggttt tttagtacca agcgaaatta cagtgtcaga atttctatta gattttctaa
    20161 ataaatatag tgaaaatata tctttagcta catataataa ttatgttagt atttgtaaga
    20221 attacattaa tccatctatt ggaaaatata aaatacaaga cttacatccg gttcacatac
    20281 aaaactacat agataaacta tcttataaac taaatcctca atcaattaag attcatataa
    20341 atatattgaa acttgcaata aaaagagctt atagactcaa attaataaaa gaaaatgtta
    20401 tggatagtat agaggctcca agatataaaa aatttaaaaa tgagatttat gatagagaac
    20461 aaatgataaa attattagat ttagcaaaaa atacagaaat ggaattacct attaatttgg
    20521 ctattggatt aggtcttaga atttcagaag ttttaggtct aacttgggat aatattgatt
    20581 ttgaagaaaa tacaataaca gtaaataaga taacttcccg aattaatggt tctgttattc
    20641 tcaaagagcc aaagacagaa agctctgtta gaaaaatatc ttctcccaaa gaattaatgt
    20701 ctttattaaa agaatataaa ataaaacaga ataaaaattt attaaaatct tccattagaa
    20761 ataataataa tttgttgttt ttcaataaga aatgtgaacc tattgctgaa gatgttatga
    20821 gtaaaaaatt taaaagattt ttagaaaaga atgaattacc tcatattaga ttccatgatt
    20881 taagacactc acatgttact ttacttataa attctaaagt acctataaag gttatatccg
    20941 agagagtagg acactcaaat ataagtacta ctctaagcgt ttattctcat gtacttaaag
    21001 aaatggataa ggaggcttct gacaaaattt ctgaaagttt atttaatgct aattaatatt
    21061 aatttatctt agctttaa
//
LOCUS       DAEPKC010000071        20976 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.071, whole genome shotgun sequence.
ACCESSION   DAEPKC010000071 DAEPKC010000000
VERSION     DAEPKC010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20976)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20976)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20976
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.071"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(<1..1742)
                     /locus_tag="KR294_002610"
     CDS             complement(<1..1742)
                     /locus_tag="KR294_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0240675.1"
                     /translation="MTLFRIAMQNVKNSFFNYLMYFISIVFSVFVFFSFKSIEYNEAL
                     SSLGEKTRMSINTSSIVIVVFVFLFIYYSNSFFFNRRRREVGTYSLLGMRKNQIGKIF
                     LYETFLMGIVAILIGIFLGLLFSKLMTMMLVKLMNEMIVVNMNLSIKALVQTLAVFLI
                     IFIVIGIRNTIVIRNKRIIELFNKYPEKYKFKKFIKLKCVLGVLLIAISYLMSISYFI
                     AENIMLSVFILVTIIPGTFLFFSSTMYMIIDAVKKRKSFYYKGQNLIAFSELGFKLKS
                     NSSVLAVIAILIATSVTMLGFTISLYYDIDRNISENYKYSYTINLGNSYVNNEIDKLL
                     YKYKKDNKIIFDKIIELIDKDINIEMYYKNRNSYIEDRTSVDIIRESDFKKLRQYQNN
                     NYEELTSKESVYYVSDSYKKIFFKDFEIEKINLHIKDANEYDINLFKVQKSILEPEIN
                     SQATFDLIVVKDDVFNQLKLHGNSRLIRLIDIKNEKKELDLTLKLKNIVSENMKFTYP
                     FNFTSSIESYDNLIKLSGLMLFIGIFLSVVFLLCTGSIILFKQLSNIYDDKERYIMLI
                     KLGANNKDIEKIIS"
     gene            complement(1729..2496)
                     /locus_tag="KR294_002611"
     CDS             complement(1729..2496)
                     /locus_tag="KR294_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003722224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0240676.1"
                     /translation="MEEILSVENIKKEYGRKGSKHEALRGITFKVYKGEFVGIMGSSG
                     AGKSTLLNIISTIDLPSSGDIYINGKNTIKMKQNELADFRRDNLGFVFQDSNLLDTLT
                     IKENIMLPLSLKNERVSVIENRIKEISKELNIESILDKYPGEVSGGQKQRGAVCRAIA
                     TKPSLVLADEPTGALDSKSARDLLNCLLKLNKDSNKTILMVTHDAISASFCNRILFIK
                     DGIIFTEIVKGESNREFYNKIVNTVSLIGGVNKNDFI"
     gene            2784..3458
                     /locus_tag="KR294_002612"
     CDS             2784..3458
                     /locus_tag="KR294_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0240677.1"
                     /translation="MFKIMVVEDDVSLKNIIAKCLTKWGHDVHQIENLENIIEEFKNY
                     NPELVLLDINLPFYDGFHWCNEIRKISKVPIIFISSRNSNMDVIMGVNLGADDYIQKP
                     FSVDVLVAKVNALLRRTYNFVDNNSNQIIHNGVTLDLSTATINYEDNTIELTKNEIKI
                     LHELMKYKGQIVSRNKLMKKLWDNDWFVDDNTLTVNVNRIRSKLNEIGLEDFIETKRG
                     LGYIIS"
     gene            3482..4486
                     /locus_tag="KR294_002613"
     CDS             3482..4486
                     /locus_tag="KR294_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH0240678.1"
                     /translation="MSFKDFLKDKLGFLVYNFTFLIFTVSVIIFSPVDVFLTDTILYI
                     LVVNVVFLFLYLFISYIKKNKFLDKIKNDTFKINMNDIELARCKNEEKIYLNIIKNHQ
                     YQCNNIINNNIEKFEENKEILNMWVHDVKIPIAIIKLILEQNENLIDEKISDDIDSEI
                     FRIENSVEKILYLSRLEDFHKDFLIQEVNIEKIIRNIIKKYSKYFISKKIILDLNNLN
                     FKVLSDEKWLYFIFEQLLSNSLKYSSLGDNISIYCKRTKNYLQLRVEDTGCGIKKEDL
                     NRIFNKGFTGNNGRNNSKSTGLGLYLVKELCDKLGHKIDVDSEYNQYTKFTITFKCDL
                     "
     gene            4598..5827
                     /locus_tag="KR294_002614"
     CDS             4598..5827
                     /locus_tag="KR294_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HBH0240679.1"
                     /translation="MSFLKKFKNKRFRNNSFKSNNFRNSSFGSSGFKSKNKGFKNNPF
                     KNKRFKIYAGIAVIILLILGVLAYVDSKNTELQANENFIETYTIPENEKIFINGMVVP
                     KQTKDFNISGDYELSDVNVTNGQKVNQGDLLFTAKNPTIIAEIDSLKSQLSQYKKQKI
                     SLSDIAENKDAIASINAQITALNSQIASLDKKAYDRVTAPFDGTVYLNDQTGNPDQPV
                     SFMTIQGLEFYMKGQASEQDLPKMKIDQMVNILVFSTDQKLTGRISFISDKPSTPNTE
                     MGAQQNTLSYYDINIAFDNQEGLVNGFHLQASLEVANSSFKIPASCVLKDNKHSYVFK
                     DLDGILKKQIVDVASQNDDFAVVRGGLEQGDIIIKHPTKEMKEGDPVQGDGVTAGSNN
                     GDTTPNKKVEEVTMDVN"
     gene            5835..6509
                     /locus_tag="KR294_002615"
     CDS             5835..6509
                     /locus_tag="KR294_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0240680.1"
                     /translation="MLIKLENIQKYYKVGKDELHVLKSLNLEIESGEFVMIMGKSGSG
                     KTTLLNILGFLDVFDEGRYIFDGTDVTNLSENERSVFRNINIGFVFQQFNLIETLNVY
                     QNVELPLIYNKALKKSNREEIVKDKLSSVGLLDKLKQKPLQLSGGQQQRVAIARCLAN
                     DPQIIFADEPTGALDSETSREIMELLTRLNKQGKTIIMVTHDQDLTKYATKVIRLKDG
                     VFTSEV"
     gene            6512..7744
                     /locus_tag="KR294_002616"
     CDS             6512..7744
                     /locus_tag="KR294_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0240681.1"
                     /translation="MSLLKNSLANLKGHKLRVFVALLWIIIGITSVILVSSIGNGFQK
                     EIKKSVNNVNPNKTTISFESADNTGLTDDMSIFLKPFNAKDLEELSFVEGVERIAPSR
                     DGFNLDSVYSSQASFDKKTTYVDVGPVKKDSKINLICGRDFSLDDEKRKVILLTLQST
                     SEIFENPEDALGHGININGTIFEIIGVLDDSQQNQAGGFFGGYQDMQFTTSLVPKKAF
                     DTLMSQNSYSNEIYQLDLVSSKGYNVNEVANNVIAKLYEMHPGINGSYTTPDPTEQTA
                     YLESINSNVNKYVSIITVVAMFVGGIGVMNIMYVSVMERQREIGIRRAIGAKPRSILF
                     QFLVEAVFITVCGGILGTIVGFAATNYVSKYIGFEAIPSLNSLFYAIVATILTGVVFG
                     LIPAFKASKLDPIKAIYK"
     gene            complement(8030..9295)
                     /locus_tag="KR294_002617"
     CDS             complement(8030..9295)
                     /locus_tag="KR294_002617"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HBH0240682.1"
                     /translation="MILIKNGRVIDPKSQRDENIDLIIKENKIYKIGKFDESDEYEKI
                     IDASGNVVAPGLVDVHVHFRDPGFTYKEDIESGAKSAARGGFTTVICMANTNPIVDNE
                     DTFNYVKEKSKNACINVLQAAAITKGFEGKELVDMEALKKAGVPGFTDDGLPLMDSNL
                     IMEAMIKAKELDVPLSFHEEDPSLVGNPGVNAGKVASELGLKGASSVAEDVMVARDCM
                     LALKTGAKVDIQHISSGVSVDMVRFAKYLGANVVAEASPHHFTLTEEDVLEFGTNAKM
                     NPPLRSKWDRDKIIEGLNDGTIEIIATDHAPHSKEEKDREFIKAPSGIIGLETSLALG
                     ITNLVHKNHLSMMQLIEKMSINPAKLYNLNIGFIEEGAVADIVIFNPEEEWTVESFVS
                     KADNSPFKGKSLYGKVNYTICNGEIVYNA"
     gene            complement(9348..10496)
                     /locus_tag="KR294_002618"
     CDS             complement(9348..10496)
                     /locus_tag="KR294_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF362 domain-containing protein"
                     /protein_id="HBH0240683.1"
                     /translation="MKSVSVRSCKTYNYEEVKLSIEKNLEDIGGIDKFVKKGSKVLIK
                     PNLLMKKKPEEATTTHPMVVKVVCEKLLELNCDITIADSPGGPYNQSSLKSIYKASGI
                     EEVANELGIKLNYDVSDVKIHSEKAHVLKYMDIIKPIVDSDYIINLCKLKTHIMATFT
                     GGTKNLYGCIAGLKKAEIHYRFPTEELFCENVLLDICDYIKPTLTIMDGIVGMEGDGP
                     SAGTTREIGVLLASQNPYAIDVVACKIISLLPNKVATIRGAIKRGYIQEDFSDIEILG
                     EDIKDLIIKNYKIPNVSKDLRLFSVKLPKFLNEPISKLITPKPVVRFQDCIKCGKCKE
                     ACPASTIEIGTKGAIIDLSKCIRCYCCHELCPKKAIDVKRNFVFKYVK"
     gene            complement(10596..11141)
                     /locus_tag="KR294_002619"
     CDS             complement(10596..11141)
                     /locus_tag="KR294_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH peroxidase"
                     /protein_id="HBH0240684.1"
                     /translation="MKKFVCTVCGYIHEGDAAPAQCPVCKVGADKFEEMKGEMVWADE
                     HRIGVAQGVDAEIIEGLRANFTGECTEVGMYLAMSRQADREGYPEVAEAYKRIAFEEA
                     EHAAKFAELLGEVVVADTKENLRVRVDAEYGATDGKLKLAKRAKELGLDAIHDTVHEM
                     CKDEARHGKAFLGLLNRHFGK"
     gene            complement(11364..12308)
                     /locus_tag="KR294_002620"
     CDS             complement(11364..12308)
                     /locus_tag="KR294_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HBH0240685.1"
                     /translation="MQKNKKEGALLKKYFGEIGLIFIAIIWGSGFVATQFALDGGLTP
                     LQIITLRFFLAAIIMNLLFFKQIRANMGKKLLKAGGILGIFLFLAFTVQTIGLMYTTP
                     SKNAFITAANVVIVPFIGFILYRRKLDKIGIISSLVALIGIGILSLEADFSINFGDFL
                     TLICSFGFAFHIFFTSEFAKDNNPMALTAIQFTVAFLMSVVVQTFAGQLKMEAELSGY
                     MGTMYLAVFSTTIGFLFQTICQKRVDGTRTAIILSTEAVFGTIFSIIILKELITAKLV
                     IGSILIFVAIITAETKLSFLKSKKVKLKDSEESSLESI"
     gene            12694..13575
                     /locus_tag="KR294_002621"
     CDS             12694..13575
                     /locus_tag="KR294_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase"
                     /protein_id="HBH0240686.1"
                     /translation="MVKKRKKKTVTLTILVVIVIGIFSMAWADMSRKKEMKETQERLK
                     AERLEKERIEKEKNEPIIGAKKEAVKEYGYDAKIVWDKLNKYDYSNNGEKIVFLTFDD
                     GPSTTNTPQVLDILKRHGVRGTFFIKGDSLERKGANEILKRTFDEGNAIAHHSYTHDY
                     KKLYPNRSLNLDTFVNELNKTDEAMKKVLGKNFSSNVVRCPGGYMSWKNMEPLGNYLK
                     EKNMASIDWNALNADAEGKKKNAQELFEHAKKSSEGKEMVVLLMHDTYGKQETVNALD
                     QIITYFKDNGYQFKILI"
     gene            complement(13636..14844)
                     /locus_tag="KR294_002622"
     CDS             complement(13636..14844)
                     /locus_tag="KR294_002622"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HBH0240687.1"
                     /translation="MKSIDEQMRIIMKGVDDLIDEKELREKLIKSEKEGKPMIVKLGL
                     DPSAPDIHLGHTVVLRKMKQLQDLGHQIVIIIGDFTGKIGDPTGKSKARKALTTEQVL
                     ANAKTYEEQIFKVLDKEKTIVRFNSEWLAKLNFEDVIKLAATITVARMLEREDFKKRY
                     EGQMPISVHEFFYPLMQAYDSIALEADIELGGTDQRFNLLMGRSLQREFGMESQIVIM
                     MPLIEGLDGKEKMSKSLGNYIGIDEEAGIMYQKSMEIPDELIIKYYNLVTDVHPDEVN
                     KIESQLKEGSVNPRDIKMNLAREIVTLYHGEESAKEAEERFKSVFQKGQIPEDIQTIQ
                     VKEDGFDLIEVLVSNEIVKSKSEVRRLASQGGVKVNGEKVEDLSTIVKESELVVQIGK
                     KKFVKIELVK"
     misc_binding    complement(14917..15169)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(15321..16310)
                     /locus_tag="KR294_002623"
     CDS             complement(15321..16310)
                     /locus_tag="KR294_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2232 domain-containing protein"
                     /protein_id="HBH0240688.1"
                     /translation="MIYGGSVLNTTKKLTEAALLSSLFIVVTIIAVSTGFGYAIYLDF
                     IVPVFFCIICLKCDLKYTILSGITSLLIISLVLGNLGTAIWASQSVLLGIMCGYLINK
                     PTMVMDDLVYGSVFGVIVMVFIDIYASTLIGYSFMKEFQGYSKWIYFNGYTNFIYYLM
                     IALFPFGMVFCIYLLSLILGNKLHILDSNSLKKFLIFKNFRNLNQFLCCSKKAFYICV
                     SYLAIFEVLKLLNVKVDSVYLKTIFISITYISVYFIIRDSCMSLQNFIIAKFRKLLYA
                     RILFLIIILLLFFIFDVTVISLIIINAFLNKKINIRLSQSNIVNKQINLLIEK"
     gene            16462..16902
                     /locus_tag="KR294_002624"
     CDS             16462..16902
                     /locus_tag="KR294_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH0240689.1"
                     /translation="MFKIKHFNDLSLDEFYEIAKSRYEVFACEQKIFSLNDYDDIDKS
                     SYHIFLKENGLICAYARIIPKEYSSYNDVSIGRVLVLSSHRRKGLAKQMMDCAIDFIK
                     VNLHENNITLSAQTYIKNLYLSCGFKEISEVYDEAGIEHIKMRL"
     gene            17229..17456
                     /locus_tag="KR294_002625"
     CDS             17229..17456
                     /locus_tag="KR294_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HBH0240690.1"
                     /translation="MKNLNDIQVKKTVKVEDILSSGNLRERMLALGLTRGAVIDVVRK
                     GPKNNLTVYKIRGSKIALRQEESSLILVSDI"
     gene            17482..19602
                     /gene="feoB"
                     /locus_tag="KR294_002626"
     CDS             17482..19602
                     /gene="feoB"
                     /locus_tag="KR294_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HBH0240691.1"
                     /translation="MGLTHNSTKMSSLKDMFDIDNKEDQFVIALAGNPNTGKSTVFNH
                     LTGLRQHTGNWPGKTVATARGNFKYKNTEYALIDLPGTYSLFALSQEEIVARDFICFG
                     NPDAVIVVCDATCLERNLNLVFQVMELTDKVILCINLIDEARKKGITIDKKLLEDSLG
                     IPVILTAARNGSGMDELLDTLNDVSFDKYKLNNKPVRYNENIENVVKSIQPELDNIIP
                     GINSRWLGLRLIDGDESIFESMSNYIDKDSIDAINEVKKKIPDNINKQKIRDEFTKIN
                     YDYAKKLSDECCSNVAKKSTDREEKVDKILTSKIFGLPIMLLLLGTILWITIEGANYP
                     STLLSNLLLGFEPSISGILNSINCPSWLNDMLVLGLYRTLAWVISVMLPPMAIFFPLF
                     TLLEDFGYLPRVAFNLDHLFKKACAHGKQCLTMCMGFGCNAAGVIGCRIIDSPRERLI
                     AILTNNFVPCNGRFPTLIAISTIFFSSVITNSFVSSVATALCITLLIILGVIITLLVS
                     YTLSKTLLKGVPSTFTLELPPYRVPQIGRTLYTSIIDRTIFVLGRAVMVAIPAGVITW
                     IFANIYIGDLSILSHVANFLDPLAKLIGLDGFILLAFILGFPANEIVVPILLMAYLAT
                     GSMIELDSFSALGQVLREHGWTYLTALNVMLFSLLHWPCATTLLTIKKETGSLKWTAL
                     GFLMPTILAFVVCFLTTTVYNLFI"
     gene            complement(19735..20553)
                     /locus_tag="KR294_002627"
     CDS             complement(19735..20553)
                     /locus_tag="KR294_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH0240692.1"
                     /translation="MEKQYFTTGEFAKLCGISKQTLIFYDKIGIFSPEYKDKNNYRYY
                     SVYQYDTLDILQSLREIGMSLEEIKEYIQNRTPQLCVKMLKEEEKKIREKIKKLRKIS
                     SKMQNRINITVEGISKMNSEEIYISKKFEEYLVLSSDLSNMSNSDFMMELIDFTNYCK
                     SKNLYQGYELGVIVSNENIKNGDYLSISSFYLKIDKKIKDKKLYVKPEGMYACIKHIG
                     KYEDSYKSYEKLKKYIYENEYKIVGNSYEESILDFFCESNEDNYMTEISIQVSR"
BASE COUNT         7444 a         3133 c         2634 g         7765 t
ORIGIN      
        1 tttgatatta ttttctcaat atctttatta tttgctccaa gttttattaa cataatatat
       61 ctttccttat catcatatat atttgataat tgtttaaata agattatact acctgtacat
      121 aaaagaaata ctacagacaa aaatatgcct ataaacagca ttagaccact taattttatc
      181 aagttatcat aactttcaat acttgatgta aaattaaaag gataagtaaa tttcatattt
      241 tcacttacta tattttttaa ttttaaagtc aaatccagtt cttttttttc attttttata
      301 tcaattaatc ttattaatct agaatttcca tgtaatttta actgattaaa tacgtcatct
      361 tttactacaa ttaaatcaaa cgtagcttgt gaatttattt ctggctccaa gatgcttttt
      421 tgtactttaa acagatttat atcatactca tttgcatctt taatatgcaa gtttattttt
      481 tcaatctcaa agtctttaaa aaatattttt ttgtatgaat cagaaacata gtacacagat
      541 tcctttgaag ttaattcttc ataattgtta ttctgatatt gtcttaattt tttaaaatca
      601 ctttctctaa taatatctac agacgttcta tcttctatat aactatttcg atttttataa
      661 tacatttcaa tatttatatc tttgtctata agttctatta ttttatcaaa gattatctta
      721 ttatcttttt tatatttata taataatttg tcaatttcgt tatttacata agaatttcct
      781 aaatttatgg tataactgta tttataattt tcacttatgt tcctatctat atcgtaataa
      841 agtgatatgg taaaccctag catagttaca cttgtagcta ttaatattgc tattacagcc
      901 aatacactac tattgctctt taatttaaat ccaagttcag aaaatgcaat taaattctgt
      961 cccttataat aaaaactttt tctcttctta acagcatcaa taatcatata catagttgat
     1021 gaaaaaaata aaaaagttcc aggtattatt gtaactaata taaaaactga aagcataata
     1081 ttttcagcaa taaaataact aattgacatt aaataagaaa tagctattaa taaaacacca
     1141 agtacacatt ttaactttat aaatttttta aacttatact tttctggata tttattaaat
     1201 aactctataa ttctcttatt tctgataact atagtatttc ttattccaat aactatgaat
     1261 attattaaaa ataccgctag tgtctgaact aaggccttta tacttaagtt catatttact
     1321 actatcattt cattcattaa ttttacaagc atcatagtca taagctttga aaataacagt
     1381 cctaaaaata tacctattag tattgcaact atacccatca aaaaagtttc atataaaaat
     1441 atttttccta tctgattttt cctcattcca agtaaactat aagttcctac ttctcgccta
     1501 cgtctattga aaaaaaatga gtttgaataa tatataaata aaaatacaaa taccactatt
     1561 acaattgaac ttgtattaat actcatccta gttttctctc caagtgaact caacgcttca
     1621 ttatactcta tagatttaaa actaaaaaat acaaatacac taaatacaat tgaaataaag
     1681 tacattaaat aattaaaaaa actattcttt acattttgca ttgcaattct aaataaagtc
     1741 atttttatta actcctccaa ttaaggaaac tgtatttact attttattat agaactctct
     1801 gttactttct ccctttacaa tttctgtgaa tattattcca tcctttataa agagtattct
     1861 attgcaaaaa ctcgcactta tagcatcatg agttaccatc aatattgttt tattgctgtc
     1921 tttgtttaat tttaatagac aattcaacaa atccctagca gatttagaat ctaatgctcc
     1981 tgtaggctca tctgcaagta ctaatgatgg ttttgttgct atagctctac atacagctcc
     2041 tctttgcttt tgtccaccag aaacttcgcc agggtattta tctaatatag attctatatt
     2101 taattctttt gaaatctctt ttattctatt ttctattact gatactcttt cattttttaa
     2161 agaaagaggc aacattatat tttcttttat tgtaagtgta tccaaaagat tagaatcttg
     2221 aaatacaaag cctagattat cacgtctaaa atctgccaat tcattttgct tcattttaat
     2281 agtattcttt ccatttatat aaatatctcc tgatgaaggt aaatctattg tagaaataat
     2341 atttaaaagt gttgatttac cagcaccgga agaccccata ataccaacaa attctccttt
     2401 ataaaccttg aaagttattc ctcttagagc ttcatgtttt gaaccttttc ttccatactc
     2461 cttttttata ttttcaacag ataatatttc ttccatagtt aataatcacc tttcatcaca
     2521 attagttatt tatcaattct cacaaatata ttatatatat taaaatggct tttaaacatt
     2581 taattatatt aatttaaggt tacattttcg taagtattaa ttatatttct tcaaatttat
     2641 tgcaattatg tttaaaatat aatttatcaa gtaaaatata gttatattaa tataattatt
     2701 ttaggtaata aggtagaaat attttaattt atcaagtaga atatagttat gttaatataa
     2761 ctattttgaa ttaggaggta agaatgttta aaataatggt agttgaagat gacgtctcat
     2821 tgaaaaatat catagcaaag tgtcttacta aatggggaca tgatgttcat caaatagaaa
     2881 atcttgaaaa tataatagaa gagttcaaaa actataaccc agaattagtt ttattggaca
     2941 taaaccttcc attttatgat ggttttcatt ggtgtaatga aataagaaaa atttcaaaag
     3001 ttcctataat ttttatttct tcaagaaatt ctaatatgga tgtaataatg ggtgtaaatt
     3061 taggtgcaga tgattatata caaaaacctt tttctgtaga tgtcttagta gctaaagtta
     3121 atgccctttt aagaagaact tataattttg ttgataataa ctcaaatcag attattcaca
     3181 atggtgttac tttagattta tcaactgcaa caataaacta tgaagataat actattgagc
     3241 taacaaaaaa tgaaatcaaa attctccatg agcttatgaa atataagggg cagatagtaa
     3301 gtaggaataa actcatgaaa aaattatggg ataatgattg gtttgtagat gataatacat
     3361 taactgtcaa tgtaaataga atacgctcaa aattaaatga aattggttta gaagatttta
     3421 tagaaacaaa aagaggattg ggttatataa tcagttaaaa caattctaag taggtgaatt
     3481 tatgagcttt aaagattttc tcaaggataa actaggtttt ttagtataca attttacttt
     3541 cttaattttt acagtatcag ttattatatt ttctcctgta gatgtttttc tgactgatac
     3601 tattttatat atattagttg taaatgttgt gtttttattt ttatatctat ttattagcta
     3661 catcaagaag aacaaatttt tagataagat aaaaaatgat acattcaaaa ttaatatgaa
     3721 tgatatagaa ttagctagat gtaaaaatga agaaaaaata tacttgaaca ttattaaaaa
     3781 tcatcaatat caatgtaata acataataaa taataatatc gagaaatttg aagaaaacaa
     3841 agagatttta aatatgtggg tacatgatgt aaagatacct atagctataa taaaactcat
     3901 tcttgaacaa aatgaaaatt taattgatga aaaaatttca gatgacatag atagtgaaat
     3961 atttagaatt gaaaactccg ttgaaaaaat tttatattta tcaagactcg aagattttca
     4021 taaggatttt ttaattcaag aggtaaatat tgaaaaaatc attagaaata ttataaaaaa
     4081 atactcaaaa tattttattt caaaaaaaat tattttagac ttaaataatt tgaattttaa
     4141 ggttttatct gatgaaaaat ggctatactt catattcgag caattattga gtaattccct
     4201 aaaatactcc tcattaggag ataatatatc tatctattgc aaaagaacca aaaattattt
     4261 acaattaaga gtggaagata ctggttgtgg tataaaaaag gaagatttaa atcgaatatt
     4321 caataaggga tttacaggta ataatggaag aaacaattct aaatctacag gtcttgggct
     4381 ttatttagta aaagaacttt gtgataagct tggtcataaa attgatgtag attcagagta
     4441 caaccaatat acaaaattta ctattacatt caaatgtgat ttatagtatc ttattattga
     4501 tagtttattt tcattaactt atattcaact tcttatagta attctatatg tacatcccag
     4561 tatataatta agtagttttt ataaaaagga ggaagacatg tcttttctaa aaaaatttaa
     4621 aaataaaaga tttagaaata acagttttaa aagtaacaac tttagaaata gcagttttgg
     4681 aagtagtggc ttcaagtcta aaaataaagg ttttaaaaac aatcccttta aaaataagag
     4741 attcaaaata tatgcaggaa tagcagtaat catactttta attctaggag ttcttgctta
     4801 tgttgattcg aaaaacactg aattacaagc taatgaaaat tttatcgaaa catatactat
     4861 tcctgaaaat gaaaaaatat ttataaatgg gatggttgtt cctaagcaaa ctaaggactt
     4921 caatatatct ggagattatg agttaagtga tgttaatgtt acaaatggtc aaaaagtaaa
     4981 tcaaggagac cttcttttta ctgctaaaaa tccaactata atagcagaaa tagatagttt
     5041 aaaatcacaa cttagtcaat acaaaaaaca aaaaatatca ctttctgata ttgctgaaaa
     5101 taaagatgct attgcttcta taaatgcaca gataactgct ttaaactctc agatagcttc
     5161 tctggataaa aaagcttatg acagagttac tgctcctttt gatggcacag tatacttgaa
     5221 tgaccaaact ggaaatccag accaaccagt ttcatttatg actattcaag gtctagagtt
     5281 ttatatgaaa ggacaagcaa gtgaacaaga tttacctaaa atgaagattg accaaatggt
     5341 caatatacta gttttttcaa ctgaccaaaa gcttactggt agaataagtt ttatatctga
     5401 taaaccatct actccaaata ctgaaatggg agctcagcag aatacactat cttattatga
     5461 tataaacata gcatttgata atcaagaagg attagtaaat ggattccatc ttcaagcatc
     5521 acttgaagta gctaattcaa gctttaaaat accagcatct tgtgtactta aagacaacaa
     5581 acactcatat gtatttaagg atttagatgg tatattgaaa aagcaaattg tagatgtagc
     5641 aagtcaaaat gatgattttg ctgtagttag aggcggtctt gaacaaggcg atataataat
     5701 aaaacaccct actaaagaaa tgaaagaagg agacccagtt caaggcgatg gcgtaactgc
     5761 tggttctaat aatggagata ctactccaaa caaaaaagta gaagaagtta ctatggatgt
     5821 gaattaattt acatatgtta attaaattag aaaatattca aaaatattac aaagtaggga
     5881 aagatgaatt acatgtttta aaatccttaa atttagaaat tgaatctgga gaatttgtca
     5941 tgataatggg taagtctggt agtggtaaaa ctactttact taatatctta ggttttctag
     6001 atgtatttga tgaaggaaga tatatatttg atggaacaga tgtaactaat ttgagtgaaa
     6061 atgaacgttc tgtttttaga aatattaata ttggatttgt tttccaacaa tttaatttaa
     6121 tagaaactct aaatgtatat caaaatgtag agttgcctct aatttacaat aaagcactaa
     6181 aaaaatctaa tagagaagaa attgttaaag ataaattaag ttctgttggg cttttggaca
     6241 agcttaagca gaaaccactt caattatctg gtggtcaaca acagcgtgta gccattgcac
     6301 gttgcctagc aaatgaccct cagataatct ttgctgacga accgactggg gcattagata
     6361 gtgaaactag cagagaaatt atggagcttt taacaaggct caacaaacaa ggtaagacta
     6421 taataatggt tacacatgat caagatttaa ctaagtatgc aactaaggtt atacgactta
     6481 aagatggtgt gtttacttcg gaggtgtaat catgagttta ttaaaaaatt ctttggccaa
     6541 tttaaaaggt cacaagcttc gtgtatttgt agctttactc tggattataa taggaataac
     6601 ttcagtaata cttgttagtt ctataggtaa tggatttcaa aaagaaatta agaaatctgt
     6661 aaacaatgta aaccctaata aaactactat ttcgtttgaa tcagccgata acacaggtct
     6721 tactgatgat atgagtattt ttttaaaacc ctttaatgca aaagatttag aagaattatc
     6781 atttgttgaa ggagtagaaa gaatagctcc ttcaagagat gggtttaacc ttgattcagt
     6841 ttactcttca caagcatctt ttgataaaaa aactacgtat gttgatgttg gaccagtaaa
     6901 aaaagattct aaaataaatt taatttgtgg tagagatttt tctttagatg atgaaaaaag
     6961 aaaagtaatt ttacttacat tacaaagtac aagtgaaatt tttgaaaatc cagaagatgc
     7021 cttaggtcat ggtatcaaca taaatggaac tatatttgaa ataatagggg tattagatga
     7081 ttctcagcaa aaccaagctg gaggattctt tggaggttac caagatatgc aatttactac
     7141 ttccctagta cctaaaaagg cttttgacac tttaatgagt caaaattctt attcaaatga
     7201 aatttaccag ttagacttag tttcttctaa aggctataat gtaaatgaag ttgcaaacaa
     7261 tgttatagct aaattatatg agatgcaccc tggtatcaat ggttcttata ctacaccaga
     7321 cccaactgaa cagacagctt atcttgaaag cattaattcc aatgtaaaca aatatgtatc
     7381 tataataact gtagttgcaa tgtttgttgg tggtattggt gtaatgaata taatgtatgt
     7441 atctgttatg gaaagacaaa gagaaattgg tataagacgt gctattggag caaaacctag
     7501 gtctatatta tttcaatttt tagttgaagc tgtttttata acagtatgtg gtggaatttt
     7561 aggaactata gttggatttg ctgctactaa ctatgtttct aaatatatag gttttgaagc
     7621 tatacctagc ttaaatagct tattttatgc aattgtagct actatattga ctggagttgt
     7681 atttggtctg attccagcct ttaaagcttc taaactagac cctataaagg caatttataa
     7741 gtagaaattg tataaagatt ttcgattttt agattagttt atataaaaca tacttaaata
     7801 tataacgcac tattatatat gatagattag gaacttaatc tttccaaata taatagtgcg
     7861 ttctttcata aaaaggattc tcttccttac tatatctaaa ttaccaagat gttatgttct
     7921 aattgttcaa actaatactt ccaattttga ttaatcaatc tcattctcct aatatacaat
     7981 cttttacttt caatcattgt acactccgcc ttaaaaaaat aatcttaaat taggcgttat
     8041 atacaatctc cccattacat attgtataat taacctttcc atataaagat ttacctttaa
     8101 atggtgaatt atcagcttta gaaacaaagc tttcaactgt ccattcttct tctggattga
     8161 atataacaat gtctgctaca gccccttctt ctataaatcc aatatttaaa ttgtacaatt
     8221 ttgcaggatt tatagacatt ttttctatta actgcatcat actaagatga tttttatgca
     8281 ccaaatttgt tattccaaga gctaaagaag tttcaagccc aataattcca cttggagctt
     8341 ttataaactc tctatctttt tcttctttac tatgaggtgc atggtctgtt gctattattt
     8401 caatagtacc atcatttaat ccctctataa tcttatctct gtcccattta cttcttagag
     8461 gtggattcat ttttgcattt gttccaaact ccaatacatc ttcctcagtc aatgtaaagt
     8521 gatgtggtga agcttctgca actacatttg cacctaagta ttttgcaaat ctaaccatat
     8581 caacagatac acctgaactt atatgttgta tatcaacttt agcaccagtc tttagtgcca
     8641 acatacaatc tctggctacc ataacatctt ctgctacact tgatgcacct tttaatccaa
     8701 gttctgaagc tacctttcct gcatttacac ctggatttcc aactaaagaa gggtcttctt
     8761 catgaaaact aagtggtaca tccaactctt ttgccttaat cattgcctcc ataattagat
     8821 tgctatccat taaaggtaat ccatcatcag taaaccctgg tacaccagct tttttaagag
     8881 cttccatatc aactaactct ttaccttcaa aacctttagt tatagctgct gcttgtaaaa
     8941 catttataca tgcatttttt gacttttctt taacataatt aaaagtatct tcattatcta
     9001 caataggatt agtatttgcc atacatataa cagttgtaaa tccacctcta gcagcagatt
     9061 tagctccact ttctatatct tctttatatg taaacccagg gtctctaaag tgtacatgta
     9121 catccactaa acctggagca actacattac cactagcatc tattattttt tcatattcat
     9181 cactttcatc aaacttgcct attttataaa ttttattttc ttttataatt aagtcaatat
     9241 tctcatctct ttgactttta gggtctatta ctctaccatt tttaattaaa atcatattat
     9301 ttctccttta tatttttaat ttatatagac tcatataata ttatacatta ttttacatac
     9361 ttaaatacaa aattacgttt gacatcaata gcctttttag gacaaagttc atggcaacag
     9421 taacatctta tacatttact taagtctata atagcaccct tagtccctat ctctatagtg
     9481 gatgcaggac aagcttcctt gcattttcca cattttatgc aatcttgaaa tcttaccaca
     9541 ggctttggtg ttataagctt tgaaataggt tcatttaaaa attttggtag ctttacggaa
     9601 aacaatctta aatctttact tacatttgga atcttgtaat tttttataat taaatctttt
     9661 atatcttcac ctaaaatttc aatatctgaa aaatcttctt gtatatatcc tctcttaata
     9721 gcacctctaa ttgtagcaac tttatttgga agtaaactta taatcttaca tgcaacaaca
     9781 tctatagcat atggattttg tgatgctaat aaaactccta tttctcgagt agtaccagct
     9841 gaaggtccat caccttccat acctactata ccatccataa ttgtcaatgt tggttttata
     9901 taatcacaaa tatctaaaag tacattttcg caaaacaact cttctgtagg aaatctataa
     9961 tgtatctctg cttttttcaa tccagctatg catccatata agttttttgt accaccagta
    10021 aaagttgcca ttatatgagt ctttaattta caaagattta ttatataatc tgaatctact
    10081 attggtttaa taatatccat atattttaga acatgtgctt tttcactatg tatcttaaca
    10141 tctgaaacat cataatttaa cttaatgccc agttcatttg ctacttcttc aattccagat
    10201 gccttataaa tgctcttaag agaactttga ttatatggac caccagggct atctgctatt
    10261 gtaatatcac aatttaactc taaaagtttt tcacatacaa cttttacaac cataggatgt
    10321 gtagttgtag cttcttcagg cttttttttc attaataaat ttggttttat aagtactttg
    10381 cttccttttt taacaaactt atctatacca ccaatatcct ctaaattttt ttcaatagat
    10441 aactttactt cttcataatt gtaagtttta caactcctaa cagataccga cttcatatta
    10501 tctccatcct tctatcacaa cagtttattt atataattta aaaaaggaga aaccaaagtt
    10561 tctcctttta atctatgttt taattgtttt aattattatt ttccaaaatg tctgtttaat
    10621 aatcctaaga atgctttacc atgtctagct tcgtctttac acatttcatg tactgtatca
    10681 tgtatagcat ctaatcctaa ttctttagct ctcttagcta attttaattt tccatcagtt
    10741 gcaccatact cagcatcaac tctaactctt aagttttctt ttgtatctgc aactacaact
    10801 tctccaagaa gttctgcaaa tttagcagca tgttcagcct cttcaaaagc tattctctta
    10861 tacgcttcag ctacttctgg ataaccttct ctatcagctt gtctactcat tgctaaatac
    10921 attcctactt ctgtacactc accagtaaag ttagctctta atccttcgat tatttctgca
    10981 tctacacctt gagctactcc tattctatgt tcatcagccc aaaccatttc gcctttcatt
    11041 tcttcaaatt tatcagctcc aactttacat actggacatt gtgctggtgc agcatctcct
    11101 tcatgtatat atccacatac tgtacaaaca aattttttca taattaattt cctcccaatt
    11161 ttatataatt aaatttttat ttttaagttt aataacttgc tacaagaata tatatacccc
    11221 agactttata gcttaaacac taaaaataaa atttatttcc taattaattt tatcactttg
    11281 aaacaccagt atcaaccaag ttttgatgtc aaatttctac ataatacata atttatttga
    11341 ttaattagga aatagttgtc atattaaata ctttctaatg aagactcctc tgaatcttta
    11401 agtttcactt ttttgctctt taaaaaagat aatttagttt ctgcagttat gattgcaaca
    11461 aatatcaaga tactaccaat aaccaatttt gctgtaataa gctcctttaa aattattata
    11521 gaaaatattg taccaaatac agcctctgtg gataatatta tagctgttct agttccatca
    11581 actctttttt gacatatagt ctgaaataaa aatccaattg tagtactaaa tacagctaga
    11641 tacatagttc ccatgtaacc agataattca gcttccatct ttaattgacc tgcaaatgtt
    11701 tgaactacaa cagacattaa aaacgctact gtaaattgaa tagctgtcaa tgccattggg
    11761 ttgttatctt ttgcaaactc acttgtaaag aatatatgaa atgcaaatcc gaatgaacat
    11821 ataagtgtta gaaaatctcc aaaattaata gagaaatcag cttctaaaga aagtatccca
    11881 attcctataa gagctaccaa actacttatt attcctattt tatcaagttt tcttctataa
    11941 agtataaatc ctatgaatgg aactattaca acattagctg ctgttataaa cgcattttta
    12001 gatggtgtag tgtacataag tccaatagtt tgtactgtga atgctagaaa taaaaatatt
    12061 cctaaaatcc ctcctgcttt taataatttt ttacccatat tggcacgaat ctgtttaaaa
    12121 aacagtaaat tcataattat agctgccaag aaaaatctta aagttatgat ttgtagaggt
    12181 gtaagcccac cgtctaatgc aaattgggtt gctacaaagc cacttcccca tataattgct
    12241 ataaatatta gtcctatttc tccaaagtat tttttcaata aagctccctc ctttttattt
    12301 ttttgcaaaa ttataaaccc cctaaacagc aagagagttt ttctataagc attactataa
    12361 attaatatag taaatttttt cagtatttta aatctaaatt tacatacatt ttgagctcaa
    12421 atttatatcc actatttaac agtaatatat taatcatttt ttgtaaacac ctttttaata
    12481 aatttttata ttttttatat ttttttacct atactaaatt tttttataga tatttttaat
    12541 atatatgata ctttaatatt atgcaaataa tgtcatataa gttacacttt agttatctta
    12601 gttacaactt tgtcggttta ctttttctac tttcttcgat ataattataa tatatttttg
    12661 atacaattcg acaaaagggg gaatgctgta attatggtaa aaaaaagaaa aaagaaaact
    12721 gttacactta ctatacttgt tgtaatagtt attggtattt tttctatggc atgggcggac
    12781 atgtctagaa aaaaagaaat gaaagaaact caagaaagac ttaaagctga aagattagaa
    12841 aaagaaagaa ttgaaaaaga aaaaaatgaa cctattattg gtgcaaaaaa agaagctgta
    12901 aaagaatatg gatatgacgc aaaaatagtt tgggacaaac ttaacaaata cgactattca
    12961 aacaatggag aaaagatagt ctttcttaca tttgatgatg gaccatctac tactaatact
    13021 ccacaagttc tagatatctt gaaaagacat ggtgttagag gaactttctt tattaagggt
    13081 gattctcttg aaagaaaagg agctaatgaa attttaaaaa gaacatttga cgaaggaaat
    13141 gcaatagccc atcactctta tactcatgac tataaaaaac tatatcctaa cagaagccta
    13201 aatctcgata cattcgtaaa tgaacttaac aaaactgatg aagctatgaa aaaagtctta
    13261 ggaaagaatt tttcctcaaa tgtagttaga tgcccaggcg ggtacatgtc atggaaaaat
    13321 atggaacctc taggaaacta cttaaaagag aaaaacatgg catcaattga ttggaacgct
    13381 ttaaatgctg atgcagaagg taaaaagaaa aatgcacaag aattatttga acatgcaaag
    13441 aaatcttctg aaggcaaaga aatggttgtt cttttaatgc atgatactta tggaaaacaa
    13501 gaaacagtaa atgcattgga ccaaattata acatatttta aagacaatgg ttatcaattt
    13561 aaaattttaa tataataaaa aagcaagttt attgaatgta cattttatac tcaatagact
    13621 tgcttttact ttactctatt ttactagctc gatttttaca aattttttct ttcctatttg
    13681 aacaactaat tcactctctt ttacaatagt gcttaaatcc tctacttttt caccatttac
    13741 ctttactcca ccttgagaag ctaatcttct aacttcactc ttactcttaa caatctcatt
    13801 agaaactagt acttcgatta agtcaaatcc atcttcctta acttgaattg tttgtatatc
    13861 ttcaggtatt tgaccttttt ggaatacaga tttaaatctt tcttcagctt ctttagcaga
    13921 ttcttctcca tggtataatg ttactatttc tcttgctaag ttcatcttta tatctcttgg
    13981 atttactgaa ccctctttca actgagattc tattttatta acttcatcag gatgaacatc
    14041 tgtcactaaa ttgtagtatt taattataag ttcatcagga atttccatag atttttggta
    14101 cattattccc gcttcttcat ctattccaat atagttacct aaactcttac tcattttttc
    14161 tttaccatct aatccttcta ttaaaggcat cattattact atttgagact ccataccaaa
    14221 ttctctttgt aatgatcttc ccattagtaa attgaatctt tggtcagttc caccaagttc
    14281 tatatcagct tctaatgcta tagagtcata tgcttgcatt aatgggtaga agaactcatg
    14341 tactgatatt ggcatttgtc cttcatatct ctttttaaaa tcttctcttt ctaacattct
    14401 cgcaacagta atagttgctg ctaattttat tacatcttca aaatttaact tagctaacca
    14461 ctcgctatta aatcttacaa tagttttttc tttatctaaa actttgaaaa tttgttcttc
    14521 ataagttttt gcatttgcaa gaacttgctc tgttgttaaa gcttttctag ctttagattt
    14581 tccagttggg tctccaattt ttcctgtaaa atctccaatt attattacta tttgatgacc
    14641 taaatcttgt aattgtttca tctttctaag aactactgta tgccctaaat gtatatctgg
    14701 agcacttggg tctagaccca attttactat cataggcttt ccttcttttt ctgatttaat
    14761 aagcttttcc cttaactctt tctcatctat taaatcatct acacctttca taattattcg
    14821 catttgctcg tctatcgatt tcatttttca ttcctcctaa aatatttata taatctataa
    14881 tttttatttt tataataaaa aaagctttca tcctcttaaa aggacgaaag cattgcttac
    14941 gtgttaccac cttagttcat caatatctca cgatattaat ctcttagagt acaattacat
    15001 atactcgtgt actataacgt gtactaatcc gatatctctt aatggttgtt atctttcaga
    15061 gatagtgctc tgagatgtat tcaaactaaa tcaatttatt ccatttcacc aaactggaac
    15121 tctctgttaa ataaaatcta gccctacttc ttctcttcat agcatttata tattcagatt
    15181 atttcatcaa ttacaagaaa tttttcttaa cttactcata atatattatt atttttatat
    15241 tttgtcaacc ttttttatta ttatatacat gtttttttac attatactac ttttttatat
    15301 tttttaccaa tacccaaaat ttatttttca atcaaaagat ttatttgttt attgactata
    15361 ttactctgac tcaatcttat atttattttc ttatttaaaa atgcgtttat aattattaaa
    15421 ctaataactg ttacatcaaa tataaaaaac agcaataaaa ttattatcaa aaataaaatt
    15481 ctagcatata ataattttct aaacttagct attataaagt tttgtagtga catacatgag
    15541 tctctaatga taaaatagac acttatatag gttattgata taaagattgt ttttaaataa
    15601 acagaatcaa ctttaacatt caacagtttt agaacttcaa aaatggctag ataagaaaca
    15661 catatgtaaa aagctttttt tgagcaacat aaaaattggt ttaaatttct aaagttctta
    15721 aatattaaaa atttttttaa agaattagaa tctaaaatat gcaatttatt ccctaaaatt
    15781 aaacttaata aatatatgca aaacaccata ccaaaaggaa acaatgctat cattaaataa
    15841 taaataaaat ttgtataccc attaaaataa atccatttgc tatatccttg aaattctttc
    15901 ataaaactat aacctattaa tgttgaagca tatatatcaa tgaaaaccat tacaataacc
    15961 ccaaatactg aaccatatac taaatcatcc ataaccattg taggcttatt tattagatag
    16021 ccacacatta taccaagtaa tacactctga cttgcccaaa tagcagttcc tagatttcca
    16081 agtaccagag aaattattaa aagcgaagta attccagata aaatggtata ctttaaatca
    16141 catttcaagc agattataca aaaaaatact ggcactataa aatctaagta aatagcatat
    16201 ccaaatccag tactcacagc tataattgtt actactatga ataaagatga caataaagct
    16261 gcttcagtta attttttagt agtattcaaa acactgcctc cataaatcat aaattttcta
    16321 actaaagttt tgtttttaat atagtatatc actttttaaa aatattttta ataaatataa
    16381 attttaataa aggtatttat gttaaaaatg gtataatgta tcttaatatt cagtttttta
    16441 agatgctagg aggtaattac tatgtttaaa attaaacact ttaatgattt gagtttagat
    16501 gaattttatg aaatagcaaa atcaagatat gaggtatttg cttgtgaaca gaagatattt
    16561 tcattaaacg attatgatga tatagataaa agctcttatc acatattttt aaaagaaaat
    16621 ggattgattt gtgcttacgc tagaataatt cctaaagaat acagctctta taatgatgtt
    16681 tccattggta gagttttagt tctttctagt catagaagaa aaggattagc aaaacaaatg
    16741 atggattgtg ctatagattt tataaaagtt aacttacacg aaaataatat aaccttatca
    16801 gcacaaactt atataaagaa cctttactta tcttgtggtt ttaaagaaat ctcagaagta
    16861 tacgacgaag caggtattga acatattaaa atgagattat agtgttgaca agctaatatt
    16921 gttaatatat aatttaagta taaattaaat attgaattga tatttaggta tttgaaaata
    16981 ccttacatag agtcagaagg cttttgcttt ctgacttttt tattatcaaa attcaataat
    17041 tatatggatt caaagtgtta atttttattc tatattctac tttccccaaa agtaagaatt
    17101 atacccaact ttgtatgata ggcatcttgc ctatcttttt tttgtaaaag taacaaggta
    17161 ataatataat gcatagttta aaataagaag attagcccag gctaaatttc aagcatggag
    17221 gtgctattat gaaaaacctt aacgatattc aagtgaaaaa aactgtcaaa gttgaagata
    17281 tattatctag tggtaattta agagaaagaa tgttagcgct tggtcttact agaggagctg
    17341 ttatagatgt agttagaaaa ggtccaaaaa ataatttaac tgtctataaa atcagaggta
    17401 gcaagatagc tctacgacaa gaagaaagta gcttaatatt agtttctgac atttaaaaat
    17461 ttctagcagg aggatattaa tatggggttg acacataact caactaaaat gagttcttta
    17521 aaagacatgt ttgatataga caataaggaa gaccagtttg taattgcatt ggctggcaat
    17581 ccaaatacag gtaaaagtac tgtatttaat catcttacag gacttagaca gcatactgga
    17641 aactggccag gaaaaactgt agctacagct cgtggtaatt ttaaatataa aaataccgaa
    17701 tatgcattaa tagatttacc aggaacatat tctttatttg ccttatcaca agaagaaatt
    17761 gtagctcgtg attttatatg ttttggtaat ccagatgcag taatagtagt atgtgatgct
    17821 acatgtcttg aaagaaattt aaatttagta tttcaagtga tggaacttac agataaagtt
    17881 attttgtgta ttaatttaat agatgaagct agaaaaaaag gcattactat tgataaaaaa
    17941 cttttagagg attctcttgg tattccagtt attttaactg ctgcaagaaa tggctctggt
    18001 atggatgaac tattggatac tttaaatgat gtatcttttg acaaatataa attaaataat
    18061 aaacctgtta gatacaatga aaatatagag aatgtggtaa aatcaattca accagaattg
    18121 gataatatta taccaggtat aaattctaga tggttgggac ttagacttat tgatggcgat
    18181 gaaagtatat ttgaatctat gagtaattat atagacaaag attctataga tgctattaat
    18241 gaagtaaaga aaaagattcc agacaatata aataaacaga aaataagaga tgagtttact
    18301 aaaatcaact atgattatgc taaaaaactg agtgatgagt gttgttctaa tgttgctaaa
    18361 aaatcaactg atagagaaga aaaagtagat aaaatattaa catctaaaat atttgggctt
    18421 ccaataatgc tcttattatt aggtactata ttgtggatta ctatagaagg agctaactat
    18481 ccatccactt tattatctaa tttattactc ggatttgagc caagtatttc gggtatatta
    18541 aatagtatta attgtccatc atggttaaat gatatgttgg ttttaggatt atacagaaca
    18601 ttagcatggg taatctctgt aatgctacct cctatggcaa tattttttcc attatttacc
    18661 ctacttgagg attttggata tttgccaaga gttgcattta acttagacca cctatttaaa
    18721 aaagcttgtg cacatggaaa acagtgtttg actatgtgta tgggatttgg atgtaatgca
    18781 gctggagtta ttggttgtag gataattgac tctccaaggg aaagacttat agctatactt
    18841 acaaacaact ttgttccttg taatggtcgt tttcctactt tgatagctat atctacaata
    18901 ttttttagct cagttataac caactctttc gtatcaagcg tagcaactgc actttgcata
    18961 actttactga taattctagg tgttataata acattgttgg tttcttatac tctttctaaa
    19021 acgctattaa aaggagttcc gtctacattt acattagaac ttcctcctta tagagttcct
    19081 caaataggaa gaactttata tacctctata atagatagaa caatatttgt tttaggaagg
    19141 gctgtaatgg tagccatacc tgctggtgtc ataacttgga tatttgcaaa tatatatata
    19201 ggagatttaa gtatattatc acatgttgca aactttttag accctttagc taaattaatt
    19261 ggtcttgatg gttttatatt acttgctttt attcttggat tcccagcaaa tgagatagtt
    19321 gtacctatac ttttaatggc ttacctagca actggttcta tgatagaatt agatagcttt
    19381 agtgctttag gtcaagttct tagagaacat ggatggactt atttgacagc tttaaatgtt
    19441 atgctgttca gtttactgca ttggccttgt gcaacaacac ttttaacaat aaaaaaagaa
    19501 actggtagtt taaaatggac tgccttagga ttcttaatgc ctactatact tgcttttgtt
    19561 gtttgttttt taacaactac agtttacaat ttatttatat aattagtatt aactgacagt
    19621 agacatatat tagagaaacc atttaaaaat ttatatactt tattataaag catagagata
    19681 tattcaatga taagtaaaat tacttaacat ttgaatatat ctctatttta attcttatct
    19741 ggatacttgg attgaaattt cagtcatata attatcttca ttactttcac aaaaaaagtc
    19801 aagtatactc tcctcatacg aatttccaac aattttatat tcattttcat atatatattt
    19861 tttcaatttt tcgtaagatt tatatgaatc ctcatatttt ccaatatgtt ttatgcaagc
    19921 atacattcct tctggcttta catatagctt tttatccttt atttttttat ctatcttcaa
    19981 ataaaaactt gatatactta aatagtcccc attttttata ttttcattac ttactattac
    20041 tcccaactca tatccttgat acaaattttt cgatttacaa taattggtaa aatctattaa
    20101 ttccatcata aaatcactat tactcatatt actcaaatcg cttgatagaa ctaaatattc
    20161 ttcaaacttt ttggatatat aaatttcttc actattcatt ttagaaattc cttcaactgt
    20221 tatatttatt ctattttgca tcttagaact tatctttctt agttttttta ttttttctct
    20281 tatctttttt tcttcttctt taagcatttt cacacaaagc tggggagttc tattttgtat
    20341 atactctttt atttcctcta aactcattcc tatttctctt aatgattgta atatatcaag
    20401 tgtatcatat tgataaactg agtaatatct ataattattt ttatctttat attcaggaga
    20461 aaaaatacct attttgtcat agaaaattaa tgtctgctta gatataccac acaatttagc
    20521 aaattcacct gttgtaaaat actgtttttc caagggttat acactccttt tctttttgtt
    20581 gtctatatag ttactatatt ctttattatt tactaaatca agtagttatt attttagaaa
    20641 atcaatatgg ttttgatttt aaagcttaaa tatcagttag atgtcagtta taaatatttt
    20701 acccattccc atcataaaaa agatatcccc tcttaacttt tggatggaat attatattta
    20761 tacttgttag agtgaaaatt gtaataggtg ctacaataag atatttaatt aaacataaag
    20821 ttaattattg taataaaaaa tctttagata aattagagtt aaagtatgga aatatagata
    20881 gagaaaaagc tgttaaacta gaaatatttt atcaatattt aatagaactt gaatatatag
    20941 aaatgagttt attaataaga agattagata ctgcaa
//
LOCUS       DAEPKC010000072        20398 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.072, whole genome shotgun sequence.
ACCESSION   DAEPKC010000072 DAEPKC010000000
VERSION     DAEPKC010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20398)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20398)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20398
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.072"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..609
                     /locus_tag="KR294_002628"
     CDS             <1..609
                     /locus_tag="KR294_002628"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240693.1"
                     /translation="KNETVGKDTYLSNIMKQKQELNDRIRDLKYRQEVYTKKINDAIK
                     NLCKSEIRETTNNFSNIEIGIKNSIIEEKNKSTMLDENSTYLNTNDEKESLITKESNE
                     KIEEEILNDEKLEELEQKKDYKEDSNKKEKVSEDLSLVGKTREELENMLKNFINLTQE
                     EIMKLESRIEKLDKNAEEYKQNSKTNIFDKTDEQKKHINVLI"
     gene            787..1677
                     /locus_tag="KR294_002629"
     CDS             787..1677
                     /locus_tag="KR294_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240694.1"
                     /translation="MKKNILTTMITMIIILMMSMTVMAEPYQEDETSSLKKQSANERN
                     QTNIGTMDGRVQTNAISKGANYDPKYPLKGMLTQLGLNTTGKEGWDLLYGGNPNGVEL
                     RADGKYYYINKGMEGLGFYAAALSGGSYQRIGFGKLDPIEVIADGNWISYKQAQDTLT
                     VIRNFLNSFDWRNASEMERANRAAKLVTEAKYADSKYCNIVYGNLVDKRGVCGSFASS
                     FHLLTRLMGMDSLSILNPSLNHAWNYIQIDGKWYRFDGSEISAFGGSLDFDYRKLKDA
                     TREMTTYYDAKALSILGFNQ"
     gene            complement(2070..3026)
                     /locus_tag="KR294_002630"
     CDS             complement(2070..3026)
                     /locus_tag="KR294_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HBH0240695.1"
                     /translation="MENNTIQKQLRDLSKKIWHIYILNPEEENLKFIISLLDDNLALI
                     GTGKHEFYETLEEFIIGLEKDQTESEQIDFEIIDEWYSCTKVTDEAFIVYGTLWVIEK
                     DYLEKDIYVEMDTRFTMVYRVTDDMIKLIHVHHSIPNFDQMKDEYYPKTITEKAQEAL
                     AMANEFKLKSEKDLMTGLYNRHFFEVHIKEMLKTVSHGYFYIFDLDNFKQVNDIFGHV
                     RGDEILIHFSNILTKVFVNDAIIGRLGGDEFAVFEYSNQSKENVENKAKKVLELCLES
                     NSCSIGISKLENNSDTFQSLYKQSDYALYYSKRNNKGNFSWF"
     gene            3729..4724
                     /locus_tag="KR294_002631"
     CDS             3729..4724
                     /locus_tag="KR294_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH0240696.1"
                     /translation="MSIIELNELTKSYRRFEKKAGFMGSVKSLFNRKYTEKTAISSFD
                     LKIEEGEFVGLIGQNGAGKTTLIKMLTGIIAPSSGEISVMGYYPNKLENNFKKQYAVV
                     MGQKSQLFFELTPADTFLLFKELYDISNEEYKKNLDYFIELFEVSDYLNVQVRTLSLG
                     ERMKMELIVALLHNPKILFLDEPTIGLDAIAQKQIRYFLKEVNETKGTTIILTSHYME
                     DIKSLCSRSIVVENSRKIYDGSTEKLFNYFQKYKKITVSFSNETNIVFPKDCKVVEQT
                     NHKISVIVPKERGNETIKWIFDKYDVKDVMIEEEDIGSIVERIYKKGSDEYYEQL"
     gene            4702..5565
                     /locus_tag="KR294_002632"
     CDS             4702..5565
                     /locus_tag="KR294_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HBH0240697.1"
                     /translation="MSIMSNYNEASSNDSMFYKFKQSIRRYYEVAKINFKVQLIWRFD
                     VVVNMVFTIVKILFAYILWKAIFGENKIVSGFTFNSMLSYYIISSFLAGIDMSKSTSE
                     EICNRVKLGTFSKYMIIPINVQNYFIAKNFGMTCFYFVFNMISAFVWIFIFKIDFAFT
                     SNPVQILISILMIFLGFIFMMKLHFFIGILSFKFLEISFLKMIIENIVEFITGTMIPL
                     VLLPETIVTVMKVFPFYYTTYLPSMLLIGRNSNEAIQGLIILALWVLFFSVVNKVMYK
                     RMRTLFDGVGI"
     gene            5562..6356
                     /locus_tag="KR294_002633"
     CDS             5562..6356
                     /locus_tag="KR294_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HBH0240698.1"
                     /translation="MMKKNLKIIFMLLKMKLSKMMVFRFDFFGAFFVDSSLFILQLLM
                     FNSIYSHVDSIGGWQQGEMLIFIGTFSLINAINMTIFFFGIYDIPRKIQEGELDYYIT
                     KPLDPLFRLTFENINIGSSPLILASILIVLYGISELNSEITLVMIIIYIFMVLLMTLL
                     FYDVCIILRTVSFFVISSSAIMRLEDNLLPMNMKIPGVIYEGIFKVLFYLILPYGIMS
                     TIPTQILAGTITINGLIYSILIVFLFTLFMWRFWKLGMRHYKSASS"
     gene            6641..8020
                     /locus_tag="KR294_002634"
     CDS             6641..8020
                     /locus_tag="KR294_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBH0240699.1"
                     /translation="MSDVYYSENHEQDNLYEQDNLLAQRFNLFTLLKFAFPTIFMMIF
                     MGLYTIVDTIFVSRFINTNALSAINIVCPIINLIVGIGTMLATGGSAIVARKMGNGDI
                     EGANKAFSLIVLSGVVIGVIITGIGIVFMDYIIIWLGASEVLIKYCRSYLFIILVFAS
                     ANILQVLFQCLFVTAGKPQFGLWLVLGAGCANIILDYVFIVLLQMGISGAALATGVGY
                     LIPTISGMVFFSKNKGLLKFCIPRLDKRILFEACFNGSSEMVGQLSTAVTTFLFNAMM
                     MKLIGEDGVAAITIIIYSQFLLTSLYIGFSMGVAPIISYNYGSENNTQLNHVFKICIL
                     FISVASLLVFIFSISCSPIIVEIFSQRGSRVYEIARSGFYIFSFSFIFCGYNIFTSSM
                     FTALSNGKVSAILSFLRTFGFITIGLLILPNILNINGIWLAVPSAEILTLFLTVFCIF
                     KYKNRYKYM"
     gene            8468..9181
                     /locus_tag="KR294_002635"
     CDS             8468..9181
                     /locus_tag="KR294_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0240700.1"
                     /translation="MDTCFNKKILLVDDEKDIVDLIEEVLINDGFKNIIKAYNGLDAI
                     SLCKIACPDVVILDIMLPDIDGIEVCKKIREFSYCSILFLSSKNDDIDKILGLSSGGD
                     DYITKPFSPREIAFRVKAQLRRQQYQSIVPSDSEVIKIGDITIDIEGNRVYKDRNEIE
                     LTGREYHLLSYMAQNVNKIIGKERLYEQVWGVYSSICDNTIMVHIRHIREKIEDNPSN
                     PKILITVKGLGYKLVNRID"
     gene            complement(9453..10991)
                     /locus_tag="KR294_002636"
     CDS             complement(9453..10991)
                     /locus_tag="KR294_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBH0240701.1"
                     /translation="MSLLKVTNLSQCFMDKSLYEKANFDLFKGEHIGVVGQNGTGKST
                     LIKILLGEVVPDSGEIKWQPNINIGHLDQYAEINRDTTISLYLHTAFEELYKIEKEMN
                     LLYQKSAISENEQYLIKASDYQEQLIASNFYSIDNEINKIANGLGLDSIGMNRVVREL
                     SGGQRAKVILAKLLLSNHDVLLLDEPTNFLDKEHVEWLSNYLNTFNGAFIVVSHDFDF
                     LEKISTGILDIEFGMIKKYHGKYSEFLKQKSHLREDYIRRYQAQQKKIEKEETFIRKN
                     KAGVNSKIARGRQKQLDKIERIAPPSFTGKPNIQFSEIEISAQNALTITNLEVGYYYS
                     LLPKLNFSVDGGQKIVITGFNGIGKSTLLKTLVKDIPRISGDFQFSEQVKIGYYEQDL
                     KWENPDKTPLQIVADKYPKLNTKEIRRHLARCGVKEEHVSRSVSTLSGGEQSKVKLCC
                     MMLSPCNFLILDEPTNHFDAETKDALQNALKQFRGSIILVSHEEKFYKGWIDKVFNIE
                     KQLV"
     gene            11873..12328
                     /locus_tag="KR294_002637"
     CDS             11873..12328
                     /locus_tag="KR294_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HBH0240702.1"
                     /translation="MDEIDLKIINSLKKNSRASTSEISRQINLSVPAVSERIRKIEQS
                     NLIQKYTIQINREKTKYKLLAFIFINTDLSKSMKEFKKTILEYDTVLECHHISGEYDY
                     LIKVLAEDTSNLEEFISVTLKEIGGIQKANTTIVLSTIKEEFNTIKDIF"
     gene            12377..12961
                     /locus_tag="KR294_002638"
     CDS             12377..12961
                     /locus_tag="KR294_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HBH0240703.1"
                     /translation="MKVLVFLAKGFETMEFSVFVDVMGWARNDYGHDIDVVTCGFKKQ
                     VMSTFNIQVLVDKTIEEVCVDDYDALAIPGGFEEFGFYDEAYDSSFLNLIREFNSKEK
                     IIASICVAALPVGKSGVLKNRKATTYHLKNGKRQRQLSEFDVNVVNEPIVVDKNIITS
                     YCPETAPHVAFKLLEMLTSKEQMDEVKLAMGFKL"
     gene            complement(12966..13289)
                     /locus_tag="KR294_002639"
     CDS             complement(12966..13289)
                     /locus_tag="KR294_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0240704.1"
                     /translation="MKKCLDNYSCPIEATLALIGGKYKTLILWHLKDTILRFNELKKL
                     IPKATPKMLTQQLRELESDGLIIRVVYPVVPPKVEYSLSDFGKSIIPILDSMCDWGSD
                     YLENL"
     gene            13441..13959
                     /locus_tag="KR294_002640"
     CDS             13441..13959
                     /locus_tag="KR294_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBH0240705.1"
                     /translation="MNFVELAKKRYSCRNYQDRKVEKEKLEKVLDVARIAPTGGNRQP
                     QRLIVIQEKEGINKLSKAANIYDAPLAILVCGDKDKVWTRPFDGKQLTDIDTSIVTDH
                     MMLQATELGLASVWVCYFNPDIIREEFSLPDNLEPINILLMGYESKIPESPERHEKTR
                     VPLSEIVSYETL"
     gene            complement(14135..14803)
                     /locus_tag="KR294_002641"
     CDS             complement(14135..14803)
                     /locus_tag="KR294_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-binding protein"
                     /protein_id="HBH0240706.1"
                     /translation="MLEVSHKVKEIYPNIKFGVMVINITHSKPNKENFLVLKNSTIKN
                     IIEQHPEYNRKEKIKTEPVSSYIKYYKKFKKTYPVLLQLESILLKSKGIPDVGVTIES
                     MFLAELKNLLLTAGHDLDKMELPLKIELANGSEHFYGIGGKEHILTKDDLFLSDNIGI
                     LSSILNGPDNRTAITKDTKNIMYFVYGPDKISEKQIQDHLNDIKHYISSAFPDLKVNS
                     IDIF"
     gene            14918..16333
                     /locus_tag="KR294_002642"
     CDS             14918..16333
                     /locus_tag="KR294_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBH0240707.1"
                     /translation="MWITINRNSNISLSRQIYCEIKDMILDGSLKFEQKLPSSRTLSK
                     ELSVSRNTVLDAYNQLIAEGYLETRNGYGTIVAKGISGHKVDFKLNDTFRDEKDLHTN
                     KQKNYIDFRSGVPELKLFPRKELSKLYKQILYDLSDSDFRYGSTAGVWVLRVEISKYL
                     FRTRGIRCNPKNIMIVSGSTQGLSLISQLLYKSNKKVAVEDPIHKGLLKVISSIGYSV
                     VGIKVDDKGMNTNLIKSIKGISFVYTTPSHQYPLGGILPIQRRLELIKCATENDYYII
                     EDDYDSEFRYEGQPISSLYELSPNKVIYIGSFSKILSPAIRVGFMLLPDNILESYKTL
                     KMYSDVHTETILQHVLAEFIGNGGLEKYIFRMKKLYNRKRKYLIKVLNTEFKNEFKIK
                     GEAAGLHIVAHFYNVKFTESLIHKIFEAGIKVYPIQQYAIENILEYDYEIILGYAHLS
                     FDEIEKGVKILSKIIHMNQGT"
     gene            16556..17014
                     /locus_tag="KR294_002643"
     CDS             16556..17014
                     /locus_tag="KR294_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0240708.1"
                     /translation="MEIIDYIEENLTENLNLDKIAYIANYSKYHLHRMFTNVVGCTIH
                     QYIQRRRLTEAARQLIFTDKYIIDIAITVGYSTHQSFTLAFRNLYKESPQVYRNKDEF
                     YPIQQRFVLNLNHQIQSEKCISYANMNYKQRRDEINSYLNFNINCEVKVA"
     gene            17011..17595
                     /gene="clpP"
                     /locus_tag="KR294_002644"
     CDS             17011..17595
                     /gene="clpP"
                     /locus_tag="KR294_002644"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HBH0240709.1"
                     /translation="MSLVPHVIEQTGQGERSYDIYSKLLKDRIIFIGEEINDAIASLV
                     VAQLLFLESEDPDSDIIIYINSPGGSATSGFAIYDTMNYVRCDVSTICIGMAASMSAF
                     LLAGGTHGKRCALPNSEIMIHQPMGGAKGQATDVKIAVDNILKIKERLDKILSENTGK
                     SIEDIRRDTDRDNFMTALEAKEYGLIDYIMNRNE"
     gene            17907..18983
                     /locus_tag="KR294_002645"
     CDS             17907..18983
                     /locus_tag="KR294_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBH0240710.1"
                     /translation="MITISLCMIVKNEEEVIGRCLECVKDIVDEIIIVDTGSTDSTKE
                     IVSKYTDMVYDFEWIDDFSAARNFSFSKASKDYTMWLDADDIILEADREKLLKIKESL
                     DTSIDIVMAKYNVSFDENGNPTLSYYRERLFKRSSNHKWVDPIHEVVPLFGEVFYSDI
                     AISHKKLHRQDPLRNLRIFEKMISEGKTLEPRHQFYYSRELYYNARYKEAIEGFTKFL
                     DSSRGWIEDCISACRDLATCYYLINDEKSALYSLFRSFEFDEPRAEICCDIGKHMFDR
                     QKYKEAIFWYKVALTRDKNDTNGGFKSNDCYGYIPSIQLSVCYDRLGESDKAIYYHEK
                     TKEIKPNDSAVLHNENYFSKFKNS"
     gene            19050..>20398
                     /gene="bclA3"
                     /locus_tag="KR294_002646"
     CDS             19050..>20398
                     /gene="bclA3"
                     /locus_tag="KR294_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like exosporium glycoprotein BclA3"
                     /protein_id="HBH0240711.1"
                     /translation="MLLIMSRNKYFGPFDDNDYNNGYDKYDDCNNGRDDYNSCDCHHC
                     CPPSCVGPTGPMGPRGRTGPTGPTGPTGPGVGATGPTGPTGPTGPTGNTGNTGATGLR
                     GPTGATGATGPTGATGAIGFGVTGPTGPTGATGATGADGVTGPTGPTGATGADGITGP
                     TGATGATGFGVTGPTGPTGATGVGVTGATGLIGPTGATGTPGATGPTGAIGATGIGIT
                     GPTGATGATGADGATGVTGPTGPTGATGADGVTGPTGATGATGIGITGPTGPTGATGI
                     GITGATGLIGPTGATGTPGATGPTGATGPTGVGVTGATGATGATGADGATGVTGPTGA
                     TGATGANGLVGPTGATGAAGTPGATGPTGATGPTGVGITGATGATGATGPTGADGATG
                     PTGATGNTGADGVAGPTGATGATGNTGADGATGPTGATGATGADGATGPTGATGATGV
                     "
BASE COUNT         7581 a         2458 c         3384 g         6975 t
ORIGIN      
        1 aaaaatgaaa ctgtaggaaa agacacttat ttatctaata ttatgaaaca aaagcaagaa
       61 cttaatgata gaattagaga tttaaaatat agacaagagg tttatactaa aaaaataaat
      121 gacgcaatta agaacttatg taaatcagaa ataagagaaa caactaataa tttttctaat
      181 atagaaatag gtattaaaaa tagcattata gaagagaaaa ataaaagtac aatgttagat
      241 gaaaattcaa cttatctaaa tacaaatgat gaaaaagaat ctttaatcac taaagagtct
      301 aatgaaaaaa ttgaagaaga aatattaaat gatgaaaaat tagaagagtt agaacaaaaa
      361 aaggattata aagaggattc taataaaaaa gagaaagtat ctgaggactt atctttagta
      421 ggtaaaactc gtgaagagct tgaaaatatg cttaaaaatt ttataaattt aacacaagaa
      481 gaaataatga aacttgagtc gagaatagaa aagttagata aaaatgctga agaatacaaa
      541 caaaattcaa agactaatat atttgataaa acagatgaac aaaaaaaaca tataaatgta
      601 ctgatttaaa caatatgttt taaaaaaata agtttattat ataatgaaaa tataaaggta
      661 caatttcaat acacttctat taaaccaata atttatgaat cagatttaat ttcaatttac
      721 taataaccat atatttatga gttaataatt ttatgtttta aaaagaatta aataaggggg
      781 agtagtatga agaagaatat attaactact atgattacca tgattattat attgatgatg
      841 agtatgacag taatggcaga gccatatcaa gaagatgaaa catctagctt gaaaaaacag
      901 agtgcaaatg aacgtaatca gactaatata ggcacaatgg atggcagagt gcaaacaaat
      961 gcaataagta aaggtgctaa ttatgaccct aaatatcctc ttaaaggaat gttaacacaa
     1021 cttggtctta atacaacagg taaagaggga tgggatttac tctatggagg aaatcccaat
     1081 ggagttgagc ttcgagcaga tggtaaatat tattatataa ataagggtat ggaagggcta
     1141 ggattttatg cggcagcatt gtcaggtggc tcatatcaga gaataggctt tggaaaactt
     1201 gaccctatag aagtaatagc tgatggaaat tggatttctt acaaacaagc tcaagataca
     1261 cttacagtaa tcaggaattt tttaaatagc tttgactgga gaaatgcatc tgagatggaa
     1321 agagctaata gagctgcaaa attggtaacc gaagcaaaat atgcagactc taaatattgt
     1381 aacatagtct atggtaatct ggttgataaa cgtggtgtat gtggaagttt tgcaagtagc
     1441 tttcatttat taacaaggtt aatgggaatg gattcactat ctatattaaa tccatcatta
     1501 aatcatgctt ggaactatat acaaattgat gggaaatggt ataggtttga tgggtctgaa
     1561 atatcagctt ttggtggatc attagacttt gattaccgta aattaaagga tgcaacaaga
     1621 gagatgacta cttactatga tgctaaggca ttgtctatat taggatttaa tcaataaaaa
     1681 tagggggagg cttcttatag agcctttttt tattgatttg aaatttaata aggaatttta
     1741 tatgaaaatt taatcaataa aagcaaaaaa ggctctttat aaagcctttc taagtgtttt
     1801 tttaagtaaa attttttata tcaacatcag ttttaatcaa aacatataac attttggact
     1861 tacttttaaa aataaaatta ttaaaatata atattaatca tgtttttagt ttattatatt
     1921 ctataatagt ggtcatgttg actattgtag ttttattaag aatagttggt ttatataaat
     1981 atatgcaaag atagcttgtt gtttacttta cttattagta tataggacaa gatactctaa
     2041 taaatttgcc tattttaata tcttttgtac taaaaccaac taaagtttcc tttattattt
     2101 cgttttgaat aatacaaagc ataatccgat tgtttgtata aagactggaa agtatcagag
     2161 ttattttcta atttagatat acctatagaa caagaattac tctctaggca taattctaaa
     2221 accttctttg ccttattttc aacattctct tttgattgat tactatattc aaaaacagca
     2281 aattcatctc caccaagtct tccaataata gcatcattta cgaatacttt agtcaaaata
     2341 tttgaaaaat gtattagtat ttcatctcct cgaacatgac caaagatatc atttacctgt
     2401 ttaaaattat ctaaatcaaa gatgtaaaag tatccatgtg aaacagtttt aagcatttct
     2461 tttatgtgta cttcaaaaaa atgtctattg tatagtccag tcataaggtc tttttctgat
     2521 tttagtttaa attcatttgc cattgctagt gcttcttgtg ctttttcagt tattgtttta
     2581 gggtaatact catctttcat ttggtcaaag tttggaatag aatggtgaac atggataagt
     2641 ttaatcatat catctgtaac tctgtatacc atagtaaatc gagtatccat ttctacatag
     2701 atatcttttt ctaggtaatc tttttctatt acccaaagag taccatatac tataaaagct
     2761 tcgtctgtaa ctttggtaca tgaataccac tcatctataa tctcaaagtc tatttgctct
     2821 gattctgttt ggtctttttc aagacctata ataaattctt ctaatgtttc gtaaaattca
     2881 tgttttcctg ttccaattaa tgcaaggttg tcatctaata aggaaataat aaatttaagg
     2941 ttttcttctt ctggatttaa aatataaata tgccaaattt tttttgataa atctcttaat
     3001 tgtttttgta ttgtattatt ttccatagat taccccctta agatttacag tttatatttt
     3061 aatgtattat aagttgaact cttattacaa tattattata atatagaact aaagaaatta
     3121 catcctgtat aagtaaaagt atatctttta taataaaaat attacagtaa aataaccagt
     3181 tttaatatac gtattatatt tttaatttat aaacgaatat tataaatgaa atttaaattc
     3241 aaccctgaag aaataagcta aatgtattag tatataaatc catacttgaa cataaataac
     3301 ctttatgata tgatatcaat aataatatta tgagaggagt gccttgatgt cggagttata
     3361 taatggtaac caacaattaa atagttggag acacatatat tctgtataat cagaaatttc
     3421 aagtgtattt ttaatacatt taatttttgt gtcttattct gcctttatag ataactgaca
     3481 tatgacaaca aatagtattt aaaatatata ttactttgtt aaattatggt gtagtaggct
     3541 ttaatctgct acacttttat taattttgta tagtattatt ttgataacta ttttgaaata
     3601 gagagcatta atttttctag tccacaggag ttttctgttt ttgtgctgtt aaatataagc
     3661 acagagaaag gcagatatat acctgtggac tttttttata taaattatga aatatggagg
     3721 tagttaaaat gagtataatt gaacttaatg aactgactaa atcttataga agatttgaga
     3781 aaaaggcagg atttatgggg agtgtaaagt ctttatttaa taggaaatat acagaaaaaa
     3841 cagctatatc gtcatttgat ttaaagatag aagaaggaga atttgttgga ttaataggtc
     3901 aaaatggagc tggcaaaact actcttatta agatgttaac tggtattatt gcaccgtctt
     3961 ctggagaaat atctgtaatg ggttattacc ctaacaaatt agaaaataat tttaaaaaac
     4021 aatatgctgt tgttatgggc caaaaaagtc aactattctt tgaattgaca ccagcagata
     4081 cgtttctttt atttaaagaa ttatatgata tatctaatga agaatataag aaaaacttgg
     4141 attactttat cgaattattt gaggtatctg actatttaaa tgttcaagtt aggacgcttt
     4201 ctttaggaga aagaatgaaa atggaactaa tagtagccct tctacataat ccaaaaatat
     4261 tatttttgga tgaaccaact ataggcttag atgctatagc ccaaaaacaa attaggtatt
     4321 tcctaaaaga agtaaatgaa acaaaaggaa ctactattat acttacttct cattacatgg
     4381 aagatattaa gagtctctgt agtagaagta ttgttgtaga aaatagccgt aaaatatatg
     4441 atggttctac agagaaacta tttaattatt ttcaaaaata taaaaaaata acagttagtt
     4501 tttccaatga aactaacatt gtatttccaa aagattgtaa agttgttgaa caaacaaatc
     4561 ataagatatc agtaattgtg ccaaaagaaa gaggaaatga aacgattaaa tggatttttg
     4621 ataaatatga tgttaaagat gtaatgattg aagaagaaga tataggtagt attgtagaga
     4681 ggatatataa gaaaggaagt gatgagtatt atgagcaact ataatgaagc aagttcaaat
     4741 gattcaatgt tttataaatt taaacagagt attagaaggt attatgaagt agccaaaatt
     4801 aactttaaag tgcaacttat ctggagattt gatgtggtgg ttaatatggt gtttacgatt
     4861 gtaaaaattt tatttgctta tattttatgg aaagcaattt ttggtgaaaa taaaatagtc
     4921 tctggtttta catttaactc tatgttatct tactatataa taagctcatt tttagcaggt
     4981 attgatatgt caaagagtac cagtgaagag atatgtaatc gtgtaaaatt gggcaccttt
     5041 tcaaagtaca tgattattcc aattaatgtt caaaattatt ttattgctaa aaattttgga
     5101 atgacatgtt tttattttgt atttaatatg atttctgcat ttgtatggat ttttatattt
     5161 aaaatagatt ttgcctttac atcaaatcca gttcaaatat taatttcaat tttgatgatt
     5221 tttctagggt ttatttttat gatgaaactc cacttcttta ttgggatttt gtcatttaaa
     5281 tttcttgaga ttagtttttt aaaaatgata attgaaaata ttgttgaatt tattacagga
     5341 acaatgatac cacttgtact cttaccagaa actatagtaa cagttatgaa ggtatttcca
     5401 ttttattata caacatattt gccatctatg ttactaatag gtagaaacag caatgaggca
     5461 atacaaggat taattattct agcattatgg gttttatttt tttctgtagt aaataaagtt
     5521 atgtataaaa gaatgagaac attatttgat ggggtgggta tatgatgaaa aaaaatttga
     5581 aaataatatt tatgttatta aaaatgaaat tatcaaagat gatggtattt agattcgatt
     5641 tttttggagc attttttgta gatagttcat tatttatatt acaacttcta atgtttaata
     5701 gtatatattc tcatgtagac tcaatagggg gatggcaaca aggagagatg ttaatattta
     5761 taggaacttt ctcattaata aatgcgataa atatgacgat tttctttttt ggtatttatg
     5821 atattccacg aaaaatccaa gaaggagaat tagactacta tattacaaaa ccattagacc
     5881 cactatttag gttaacattt gaaaatatta atattggttc atcaccatta attctagcaa
     5941 gtatacttat tgttttatat ggaatatctg agttaaactc agagataact ttagttatga
     6001 taataatata tattttcatg gtgttattga tgacattact tttttatgat gtatgtatca
     6061 tacttagaac agtttcattt tttgttatat catcttctgc gataatgaga ttagaagata
     6121 atttattgcc aatgaatatg aaaattcctg gtgtaatata tgaaggtatt tttaaagtat
     6181 tattctattt aatcttacca tatggaatta tgtcgacaat tccgactcaa attttggctg
     6241 ggacaataac aattaatgga ttaatatact caattttaat tgtatttttg tttacattgt
     6301 ttatgtggag attttggaag ttaggtatga gacattataa aagtgcaagt agttaataaa
     6361 ttagtaaaaa tagacaatgt ataactatat ataaatacgt ttcatatgac actaaactat
     6421 gtgaacaagt atttgcgcta aaggcactga aagctataaa atgattaaag taaggattta
     6481 aaagtttctt tagtagaaat ataattgtgt aaaaaagcaa gattaattaa aactatatcc
     6541 aaataattag atataattct tatgcagaaa ggaggtctgt aaatgtctaa ttgtttggaa
     6601 tatattttaa aaataattaa tgtacagaaa aataaacaaa atgagtgatg tatattattc
     6661 agaaaatcat gaacaagata atctttatga gcaagataat ttactggcac aaagatttaa
     6721 tttatttact ctattgaagt ttgcatttcc tactattttt atgatgattt ttatggggtt
     6781 gtatacaatc gtagatacta tatttgtatc aagatttatt aatacaaatg ctctatcagc
     6841 aattaatatt gtatgtccaa ttattaatct tatagttgga attggaacta tgcttgccac
     6901 tggaggaagt gctattgtag cacgtaagat gggaaatggt gatattgagg gagcaaataa
     6961 agctttttct ttaatcgtat tatcaggagt tgtaattggg gtaataatta ctggtatagg
     7021 tattgtattt atggattata tcattatatg gttaggagca agtgaagttt taattaaata
     7081 ttgtcgttca tatcttttta ttatcttggt ttttgcttct gcaaatatac tacaagtatt
     7141 atttcaatgt ttatttgtaa cagctggaaa gcctcaattt ggattatggc tagtgttagg
     7201 tgctgggtgt gctaatataa ttcttgacta tgtgttcatt gttctgttac aaatgggtat
     7261 tagtggagca gcacttgcaa ctggagtagg atacctaatt cctaccattt caggtatggt
     7321 tttcttttca aaaaataaag ggttacttaa attttgtata cctagactag ataaaagaat
     7381 attatttgaa gcttgtttta atggttcatc tgaaatggtg ggtcaactat caacagcagt
     7441 tactactttt ttatttaatg ctatgatgat gaaattaatt ggtgaagatg gggttgcagc
     7501 tattacaata attatttatt ctcaatttct tttaacttcg ctttatatag gtttctcaat
     7561 gggtgttgca ccaataataa gttataacta tggaagtgaa aataatacgc agttaaatca
     7621 tgtttttaag atttgtatat tatttatttc agtagcatct ttattggtat ttatcttttc
     7681 tatatcatgt tcaccaatca ttgtagagat tttttctcaa agaggaagcc gagtttatga
     7741 aattgcaagg tccggatttt atatattttc ttttagtttt attttttgtg gatataatat
     7801 ttttacctca tctatgttta cagcattatc aaatggaaag gtgtctgcaa tattatcttt
     7861 tctacgtaca tttggattta taactatagg tttattgata ttgccaaata tattaaatat
     7921 aaatgggata tggttagcag taccaagtgc tgagatttta accttatttt taactgtttt
     7981 ttgtatattt aagtataaga atagatataa atatatgtag atattaaata aatagcttag
     8041 atagatattt tatgttttaa taagtaattc aattagtggt agatatatac tattgaaaat
     8101 taaagttata attgatataa agaattaata aaaataacat ataaaagttt aaaagggagt
     8161 tgaacttaaa gtttgattag aaaaagtcaa ttttaagaca actcctttta ttttactatt
     8221 gtattaatct gtatctgtaa gtgtattagt ctaatattat aaactttgga tgaaattaat
     8281 tttctatagg ttttaatgta tcatacactt tattttaaag aaacttatct taattttcat
     8341 agtgattgaa tttgtctatt agagatgtta ctattagtaa tgtaaaagca agagtagtga
     8401 atataaaaaa caagatagtg atactgcaag attagaatat aataaatttt tatggagaga
     8461 tttcaatatg gatacatgtt ttaataaaaa aatattactt gttgatgatg aaaaggatat
     8521 agtagattta attgaagaag tactcataaa tgatggtttt aaaaacatta ttaaagctta
     8581 taatggtcta gatgctattt cgctgtgtaa gatagcatgt ccagatgttg tcattcttga
     8641 tataatgtta ccagatatag atggtataga agtgtgtaaa aaaattcgag agttttcata
     8701 ctgttctatt ctttttttat catcaaaaaa tgatgatatt gacaaaatac taggtcttag
     8761 tagtggggga gatgactata taacaaagcc attcagtcca agagaaattg cttttcgagt
     8821 taaagcgcaa ttacgtagac aacagtatca aagcattgta ccatcagata gtgaagttat
     8881 taaaatagga gatattacta ttgatataga aggaaaccgt gtatataaag atagaaatga
     8941 gattgagtta actggaaggg agtatcatct tttaagctac atggctcaaa atgtaaataa
     9001 aattatagga aaagaaagac tctatgaaca agtatgggga gtatatagta gtatttgtga
     9061 caatacaatt atggtgcata tacgacatat aagagaaaaa attgaagata acccctcaaa
     9121 tcctaaaata cttataacag ttaaaggact aggatataaa cttgtgaata gaatcgatta
     9181 gaatagattt taatattaat gaagatatct caagttgaat ttttagttaa tgaggcattc
     9241 ttttatgggt gaaatcaaat gtattttcgt tatctcaaca atgaagaaga ggtctatctc
     9301 tattttgaga tagcctcatt aagtttatat cctggtaatg tactttatgt tctaataaaa
     9361 tttttttagt ttatttgcag tgaaacatta actagaacat taaaatttgc attgaaatac
     9421 caattaaata atattgtata ttgtgtataa acttatacta attgtttttc tatattaaat
     9481 actttatcaa tccaaccttt ataaaatttt tcttcatggg aaactaggat tatacttcct
     9541 ctaaactgtt tcaaagcatt ttgtaaagca tcctttgtct ctgcatcaaa gtgattggtt
     9601 ggttcatcca gaataagaaa attacaagga gataacatca tacaacataa tttaacctta
     9661 gattgttcac caccacttaa agtagataca ctccttgaaa catgctcttc cttcacacca
     9721 catctggcta gatgacgtct aatctctttt gtatttaatt ttggatattt atctgctact
     9781 atttgaagtg gggttttatc aggattttcc cattttaaat cttgctcata ataaccaatt
     9841 ttaacttgtt ctgaaaactg gaaatctcca gatatacgag gaatatcttt gactaatgtc
     9901 tttaacaagg tagatttacc gattccatta aaaccagtta taactatttt ttgacctcca
     9961 tcaacagaga aatttaattt tggaagtaaa gaatagtagt atccaacttc aagatttgtt
    10021 atagtaagag cattttgagc cgatatttca atttctgaaa attgaatatt tggttttcct
    10081 gtaaaactag gaggagctat tctttctatt ttatccaatt gtttttgtct tcctcttgca
    10141 atttttgaat ttactccagc tttattttta cgtataaatg tttcttcttt ttctattttc
    10201 ttttgttgtg cttgatacct tctaatataa tcttctctta aatgtgattt ttgtttaagg
    10261 aactctgaat attttccatg atatttctta atcatgccaa attctatatc aagaatacct
    10321 gtagaaattt tttctaaaaa gtcaaaatcg tgggaaacta caataaatgc cccattaaat
    10381 gtatttaaat aatttgagag ccattcaaca tgctctttat ctaaaaagtt tgttggttcg
    10441 tctaataata gaacatcatg gttagaaagt agtaattttg ctaaaattac ctttgccctt
    10501 tgaccaccac taagctctct aacaacacga ttcattccta ttgaatctaa tccaagacca
    10561 tttgctattt tatttatttc attatctata gaatagaaat tacttgctat tagttgttcc
    10621 tgataatctg atgctttgat tagatattgc tcattttcag atatagcact tttttgatag
    10681 agtaaattca tttccttttc tattttataa agttcttcaa atgcagtgtg taaatagagt
    10741 gatattgttg tatctctatt gatttctgca tattggtcta aatggcctat attgatatta
    10801 ggttgccact tgatttctcc tgaatctgga acaacttctc ccaataaaat tttaattaat
    10861 gtacttttac ctgtaccatt ttggccaact acacctatat gttcaccttt gaataaatca
    10921 aagttagctt tctcatacag tgatttatcc ataaaacatt gtgataaatt agttactttt
    10981 aataaactca taattcaaac tccttttctt ttattaaaaa atttatggaa ataaaaaaag
    11041 cagaggaatg gcattgtaaa atgccgacct ctgcttttgg aaaaacaaaa ggtcatagac
    11101 aagcattgtt gtctatgacc agaaaatcta tattatctat cggcaaatag gtaattttaa
    11161 ataagcatag ccaaaaaact atactaaacc tatatttgcc gatgaagata gaaagcttta
    11221 agctttcaga ttaacctcta cacaacgctt catcgtatac atttgtgtag agttaagttt
    11281 tctaacaagt ttaactaatt ctatataaat cataattatt cacatcctaa tcttagtatt
    11341 aattctagtt tatctgtatt taaattgtac ttttgtactt tgtggattat cttatttatt
    11401 taaaatatgt tttattaatt atagcttaag ttatgttatc ataatactta gttatagtca
    11461 ataagaaagt tatatttact attattatat taatttagta aatctatcat tacaaagtta
    11521 tttgaagact cgctatcaat aaaattttat agtctataag aaaattaaga ttatgagttt
    11581 tataattttg atatagggat actattttca taaatattac aacatgtaga agtatatgtc
    11641 tattattgtt gaattttcaa tgatatatta aggttctaat atattataca aaataaaaac
    11701 attaattcaa cttaaataat tttaagtatt atatgtgttt tgattaaaga aaactaaaat
    11761 tttaaggaaa aataacatat ttgtattaaa ttttattgaa atgattaaat ttatttactt
    11821 aatgtaaatt attagctaaa attgtattaa ataattaagg aggtgagtag ctctggatga
    11881 aatagattta aaaataatta attctctaaa aaagaatagt agggcttcaa cctctgaaat
    11941 aagcagacaa attaatttat cagtaccagc agtctcagag cgtataagga aaattgagca
    12001 gtcaaattta attcaaaagt acactattca aattaatcgg gaaaaaacaa aatataagct
    12061 tttggctttt atatttatca atactgattt atctaaaagt atgaaagaat ttaagaaaac
    12121 tatattggaa tatgatactg tattagaatg tcatcatatt tcaggagagt atgattactt
    12181 aataaaagta ttagcagaag atacaagtaa tcttgaagag tttatatcag tgactttgaa
    12241 ggaaattggg gggattcaaa aagctaatac aaccattgtt ttatctacaa ttaaagaaga
    12301 atttaataca ataaaagata ttttttaaat aatttactag taaagtgtta attatatttt
    12361 aggaggaaaa tagaatatga aagttttagt ttttttagca aaaggttttg aaactatgga
    12421 atttagtgta tttgtagatg ttatgggatg ggctcgtaac gattatgggc atgatattga
    12481 tgtagtgact tgtggattta aaaaacaagt tatgagcaca tttaatatac aagtattagt
    12541 tgataagacg atagaagaag tatgtgttga tgattatgat gctctagcta ttcctggagg
    12601 atttgaagaa tttggatttt atgatgaagc atatgattca tcttttttaa atctaataag
    12661 ggagtttaat tcaaaagaaa aaataatcgc ttctatttgt gtggcagcat tgccagttgg
    12721 aaaaagtggt gttttaaaaa atcgtaaagc tactacatat catttgaaaa atggtaaaag
    12781 acaaagacag ttaagtgagt ttgatgtaaa tgtagttaat gaaccaattg ttgtagataa
    12841 aaatattata acctcatatt gtccagaaac agctccacat gtagctttta agcttttaga
    12901 aatgttgaca tctaaagaac aaatggatga agttaaatta gcaatgggat ttaaactgta
    12961 atggtttata gattttctaa gtaatcagaa ccccagtcac acatggaatc taaaattgga
    13021 ataatactct ttccaaaatc agatagcgag tattctactt ttggaggaac aacaggataa
    13081 accactctta taattaaacc atctgattct aattcacgta attgttgagt taacatctta
    13141 ggcgttgctt taggaattaa tttttttaat tcattgaacc tcaatatagt gtctttaaga
    13201 tgccaaagta taagtgtctt atatttacca ccaatcaatg caagtgttgc ttctattggg
    13261 caactgtaat tatctaaaca ttttttcatt tttgggctcc tttatttatt ttaaagtatc
    13321 tttttaggta ctatattaca aaaaagtgca ttattgtaat atagtaccat agtgataaaa
    13381 ttatagcata ggttaaataa atcatcaact tagcctaata aaacaatagg gggtaaataa
    13441 atgaatttcg ttgaacttgc aaaaaaaaga tattcttgcc gtaattatca agatagaaag
    13501 gttgaaaaag aaaaacttga gaaggtttta gatgttgcaa gaatagctcc aactggtggt
    13561 aatcgtcaac ctcaaagatt gattgttatt caggaaaaag aaggtataaa taaactttct
    13621 aaggctgcca atatatatga tgcgccatta gcaattcttg tatgtggaga taaagacaaa
    13681 gtttggacaa gaccttttga tgggaaacaa cttacagata ttgacacaag tatagttaca
    13741 gaccatatga tgttacaggc aactgaactt ggattggcaa gtgtttgggt gtgctatttt
    13801 aatccagata taattagaga agagtttagt ttgccagata atctagaacc aataaatata
    13861 ttattgatgg gatatgaatc taagatacca gagagcccag agagacatga aaaaactcgt
    13921 gttcctttaa gtgaaattgt ttcttatgaa actctttaat tataaaatta agttattcat
    13981 aggataaatg taataaagtg tttgttataa acaaaattca aaataaataa tatctacata
    14041 taattaattt tagtgaagta tatctagttt aactagaatg tatacttcac taatttattt
    14101 attcaaaata tttatgagga ttttaatata ttaactaaaa tatatcaatt gaattaactt
    14161 ttaaatctgg aaaagcactt gaaatatagt gttttatatc atttaaatgg tcttgaattt
    14221 gcttttctga tattttatca ggtccatata caaaatacat aatattttta gtatcttttg
    14281 ttatagctgt tcgattatca gggccattaa gaatactaga taatatacca atattatctg
    14341 ataaaaataa atcatctttt gttaaaatat gttctttacc acctatacca taaaaatgtt
    14401 cacttccatt tgctaattct attttcaaag gtaattccat tttatcaagg tcatgacctg
    14461 ctgttagaag aagatttttc aattctgcta aaaacattga ctcaattgtt acacctacat
    14521 ctgggatacc ttttgatttt aatagaatag attctaattg aagcaataca gggtaagttt
    14581 tcttgaattt tttataatac tttatataac ttgaaacagg ctctgtttta attttttctt
    14641 tgcgattgta ttctgggtgt tgttctataa tatttttaat tgtagagttt ttaagaacta
    14701 aaaaattttc tttattaggt tttgaatgtg taatatttat aaccataact ccaaatttaa
    14761 tattgggata aatttcttta actttatgtg atacctctaa cataatatag actccttttt
    14821 attttatatt ttatgatata atcttagcaa attaaaagtg gattttatag ttccattttt
    14881 atagtaattt tatagaacca cttttggagg tattagaatg tggattacga ttaatagaaa
    14941 tagtaatata tcattatcaa gacaaattta ttgtgagata aaagatatga ttctggatgg
    15001 aagcttaaag tttgagcaaa aactgccatc atctaggact ttatcaaaag aactatctgt
    15061 atctcgtaat acagttttag atgcatataa tcaattaatt gcagaaggat atttggaaac
    15121 aaggaatgga tatggaacaa ttgtagctaa aggaatatca gggcataaag ttgattttaa
    15181 gttaaatgat acttttagag atgaaaaaga tttacatact aataaacaaa aaaattatat
    15241 agattttcgt tcaggagttc cagaattaaa actatttcca cgcaaagaac tttcaaagct
    15301 atataaacaa atactgtatg atttatcaga ttcggatttc agatatggaa gtacagctgg
    15361 tgtatgggtt ttaagagtgg aaatatctaa gtatttattt cgtactagag gaattagatg
    15421 taatcccaaa aacattatga ttgtttctgg ttcaacacaa ggtttatctt taatttcaca
    15481 gcttttatac aaaagtaata aaaaggttgc tgtagaagac cctattcata aaggcttatt
    15541 aaaggttatt tcatctattg gatattcagt tgttggaatt aaagtagatg ataagggaat
    15601 gaataccaac ttaataaaat caataaaggg gatttctttt gtttatacta caccttctca
    15661 tcaataccca ttaggaggga ttttacctat tcaaagaaga ctagagctta ttaaatgtgc
    15721 aacagagaat gattactata taattgaaga tgattatgat agtgaattta gatatgaggg
    15781 tcaaccaatt agttctcttt atgaacttag cccaaataaa gtaatttaca taggttcttt
    15841 tagtaaaata ttatctccag ctattcgtgt tggatttatg ttattaccag acaatatttt
    15901 agaaagctat aaaaccttaa aaatgtactc tgatgttcat acagaaacaa tattgcaaca
    15961 tgtattagct gaatttattg gaaatggagg tttagagaag tacatattta gaatgaagaa
    16021 gttgtacaat agaaaacgta agtacctcat aaaagtttta aacacggaat ttaaaaatga
    16081 atttaaaata aaaggtgaag cagcagggct tcatatagtt gctcatttct ataatgttaa
    16141 atttacggaa agtttaattc ataaaatttt tgaagcaggt ataaaagttt atcctataca
    16201 acaatatgca attgagaata tattagaata tgactatgaa attatactag gttatgctca
    16261 tcttagtttt gatgaaattg aaaaaggtgt aaaaatactc agcaaaataa tacatatgaa
    16321 tcaaggtaca tagataaaac atgtagcaat ctacatataa tagatgtaat taagtttaaa
    16381 ctttaaaaga aatatatatt aatatttttg tataaaaata cctgatattt ttttatcgat
    16441 actttattgc tatacactaa attaagatag caatttatat taagaaaaaa ctttttgcat
    16501 aggttataat acttaaaagg agaggataga gttgaaaaca aatacagatg ttattatgga
    16561 gataattgat tatatagaag aaaatcttac agaaaatcta aatttagata aaatagctta
    16621 tattgctaat tattcaaaat accatttaca cagaatgttt acaaatgttg taggatgtac
    16681 tatccatcaa tacatacaga ggaggagact tactgaagca gctagacaac ttatatttac
    16741 agacaaatat attatagaca tagctattac agtaggatat tctacacatc aatcttttac
    16801 actagcattt agaaatttat ataaagaatc tccacaagta tatagaaata aagatgaatt
    16861 ttatcctatt caacagagat ttgttttaaa tctaaatcat caaattcaaa gtgaaaaatg
    16921 tatttcttat gcaaatatga attataaaca aagaagagat gaaatcaatt cttatcttaa
    16981 ctttaatatt aattgtgagg tgaaagtagc atgagtttag tgccacatgt aattgaacaa
    17041 acaggtcaag gggaaaggtc ttatgatata tattcaaaat tattaaaaga tagaattata
    17101 tttataggag aagaaattaa tgatgctatt gcaagtttag tagtagctca attactgttt
    17161 ttagaatcag aagacccaga ttcagatata attatatata taaatagccc tggtggctct
    17221 gctacatcag gatttgctat atatgatact atgaattatg tcagatgtga tgtatcgact
    17281 atttgtattg gtatggctgc aagcatgagt gcttttttac ttgcaggagg aacacatgga
    17341 aaaagatgtg ctttacctaa ttcagagatt atgattcatc agccaatggg aggagctaaa
    17401 ggtcaagcaa cagatgtaaa aatagctgta gataatatat tgaaaataaa agaacgatta
    17461 gataaaattc tttctgaaaa tacaggtaaa tcaatagaag atattaggag agatacagat
    17521 agagataatt ttatgactgc actagaggct aaagagtacg ggctgattga ttatataatg
    17581 aataggaatg aataaagtat caaagtatca tattaaaatg tctgttttac aaatatatat
    17641 ataatattaa ataagagtgt ctcaaaatga actttttagt ttatgggaca ctcttttttg
    17701 tatgaaatta aatatggttt tatcatttca acaattatta ccaaatttca agtttaataa
    17761 attctactat aaaaaataca taaaagataa ggttctttag taactttctg tcgtcaaaag
    17821 tttttataaa tttaataaca aaacaagaga aaataccata tattacttat gtctgcaata
    17881 tatagaagac aaaggagttg tacattatga ttacaataag tttgtgcatg attgttaaga
    17941 atgaggaaga agttataggc agatgcttag aatgtgtaaa ggatatagta gacgaaatta
    18001 taattgtaga tacaggttct acagattcca caaaagaaat agtctcaaaa tatacagaca
    18061 tggtgtacga tttcgaatgg atagatgatt tctctgctgc aagaaatttt tcattttcta
    18121 aagcttctaa agactatact atgtggcttg atgcagatga cataatttta gaagctgata
    18181 gagaaaaatt attaaagatt aaagaaagct tggatacttc cattgatatt gttatggcaa
    18241 aatacaatgt atcctttgat gaaaatggta acccaactct ctcgtattat agagaacgat
    18301 tgtttaaaag aagttctaat cataaatggg ttgaccctat tcatgaagta gtacctcttt
    18361 ttggagaggt attttattct gacattgcaa tatctcataa aaagcttcat agacaggacc
    18421 ctctaagaaa tcttagaatt tttgaaaaaa tgatttcaga aggaaaaaca ttggagccaa
    18481 gacaccaatt ctattattct agagagttgt actataatgc taggtataaa gaagcaatag
    18541 aaggttttac taagttttta gactcatcaa gaggatggat tgaggattgt atcagtgctt
    18601 gcagagattt agccacatgt tattacttaa ttaatgatga aaaaagtgcc ttatattcat
    18661 tgtttagaag tttcgaattt gatgagccaa gagcagaaat ttgttgtgac ataggaaagc
    18721 atatgtttga tagacaaaaa tataaagaag ccattttttg gtataaggta gcattaacaa
    18781 gagataagaa tgatactaat ggaggtttta agtcaaatga ttgttatgga tatataccat
    18841 ctatacaatt aagtgtctgt tatgacaggt taggagaatc agataaagct atttattatc
    18901 atgaaaaaac aaaagaaatc aaacctaacg atagtgctgt tttgcacaat gaaaattatt
    18961 ttagtaaatt taaaaatagt tgataggtca caatcatact aaatttgaca tattatatat
    19021 agagcttaaa agctcaaata tatcaggagg tgcttttaat aatgagtaga aataaatatt
    19081 ttggaccatt tgatgataat gattacaaca atggctatga taaatatgat gattgtaaca
    19141 atggtcgtga tgattataat agctgtgatt gccatcattg ctgtccacca tcatgtgtag
    19201 gtccaacagg cccaatgggt ccaagaggta gaaccggccc aacaggtcca acgggtccaa
    19261 caggtccagg agtaggggca acaggcccaa caggaccaac cggtccgact ggtccaacag
    19321 gaaatacagg gaatacagga gcaacaggat taagaggtcc aacaggagca acaggggcaa
    19381 caggcccaac aggagcgaca ggagctatag ggtttggagt aacaggtcca acaggcccaa
    19441 caggagcgac aggagcaaca ggagcagatg gagtaacagg tccaacaggt ccaacgggag
    19501 caacaggagc agatggaata acaggtccaa caggagcaac aggggcaaca ggatttggag
    19561 taacaggtcc aacaggccca acaggagcaa caggagtagg agtaacagga gcaacaggat
    19621 taataggtcc aacaggagcg acaggaacac ctggagcaac aggtccaaca ggggcaatag
    19681 gagcaacagg aataggaata acaggtccaa caggagcaac aggagcaaca ggggcagatg
    19741 gagcaacagg agtaacaggc ccaacaggcc caacaggggc aacaggagca gatggagtaa
    19801 caggcccaac aggagcaaca ggagcaacag gaataggaat aacaggccca acaggtccaa
    19861 caggagcaac aggaataggg ataacagggg caacgggatt aataggtcca acaggggcaa
    19921 caggaacacc tggagcaaca ggtccaacag gagcaacagg cccaacagga gtaggagtaa
    19981 caggagcaac aggagcaaca ggggcaacag gagcagacgg agcaacagga gtaacaggtc
    20041 caacaggagc aacaggggca acaggagcaa atggattagt aggcccaaca ggagccacag
    20101 gagcagcagg aacacctgga gcaacaggtc caacaggagc aacaggccca acaggagtag
    20161 gaataacagg agcaacaggg gcaacaggag cgacaggtcc aacaggagca gatggagcaa
    20221 caggtccaac aggagcaaca ggaaatacag gagcagatgg agtagcaggt ccaacaggag
    20281 caacaggagc aacaggaaat acaggagcag atggagcaac aggtccaaca ggagcaacag
    20341 gggcaacagg agcagatgga gcaacaggtc caacaggagc aacaggagca acaggagt
//
LOCUS       DAEPKC010000073        20302 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.073, whole genome shotgun sequence.
ACCESSION   DAEPKC010000073 DAEPKC010000000
VERSION     DAEPKC010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20302)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20302)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20302
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.073"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            5..892
                     /locus_tag="KR294_002647"
     CDS             5..892
                     /locus_tag="KR294_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBH0240712.1"
                     /translation="MIIRIILFRDVPIYAIFKGTFRNVNLIPFYTIYQFIVDSNLDFM
                     KATVNIIENIGIFIPMGIFLPIVCKNLNKKTIIIVIILVSLAFELTQYIFALGSSDID
                     DVILNSLGGIIGINIYINMNKLFPNDINRFKAIIGTSLVLGVIGLGVISKNYHNLLTF
                     KFRPDRKISKILIEENREIIKDINKDTVDIVGTFESFKKGIITIKAGSNNKVKRPENL
                     IDSDGNIRIYLNENTKLVSYIITKESKMDIVKYEEFDVKNLDLLRRYDTINVWIDKEN
                     QPKDKHGIMASKLLIGLYE"
     gene            1007..1792
                     /locus_tag="KR294_002648"
     CDS             1007..1792
                     /locus_tag="KR294_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240713.1"
                     /translation="MEIIKYILYFFIYSFLGWTVESIGCSIASKRIINRGFLNGPICP
                     VYGFGAVIVISLLGRFNNVVIVFLLGMILTTILEYFTGFILETLFHAKWWDYSDKKFN
                     IKGRVCLKNAIYFGVMSVLIIRFIHPFIKYFVSIIPYRILISMAIITTLWTILDLIVT
                     IITLKKLDIKLNLLDDIITDLNDINVKLDKFDRGEIQALFKTINNDELEVREKINKIN
                     SKLDRIESNIILQKRVIKAFPHIKHKKQQEQLEHFKKIINEKR"
     gene            2084..3403
                     /locus_tag="KR294_002649"
     CDS             2084..3403
                     /locus_tag="KR294_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class III-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBH0240714.1"
                     /translation="MSEITSQMISTEEKKYVAKTQKIPYYPVAFKSGDGAMLYDYEGN
                     EYVDFLASAGSANVGHGNKEISQAVKEQMDDITQYTLAYFHSDPPVKLAEKLVEIAPG
                     DNDKKVLYSATGSACIDAAIKLARGYTGRTKIISMCESYHGSTYGAISISALSTNMRR
                     KMGPLLPEVYHFHYPDKNRTAKECLDEIEYAFAHYLPAEEVAAIFIEPIAGDAGIIVP
                     PVEWVQGLSKICKENGILLVSDEIQQGMGRTGKWFGIENFGVEADLIVLGKSVGGGLP
                     LGAVVGRTEIMQSLDAPAHLFTLAGNTTVCVAALKSIEIIEKENLLQKSIEMGDYIKA
                     GFEKLKEKYDIIGEIRGIGLSIGVDIVKGKGSNEKHPDATAKICYRCIQTGLIMIFLG
                     QSTLRVQPPLVITKEQVDKAMNIIDSAIDDYLNGRIGDEVYEVTQGW"
     gene            complement(3478..3906)
                     /locus_tag="KR294_002650"
     CDS             complement(3478..3906)
                     /locus_tag="KR294_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240715.1"
                     /translation="MKDNNNTNKTIQFGEKKASLENNIQKNKNIKLDNTHKVIPYPKN
                     RKKDDKKKGNKKKNTNTSKVNKNNYGHSFFNNKYKYKRKPYVIALYTVILILLAILII
                     TKLTDSTNKGNYSRNTVSDTHKNDIRNIVFNESNNFLICG"
     gene            complement(3997..5373)
                     /gene="hydG"
                     /locus_tag="KR294_002651"
     CDS             complement(3997..5373)
                     /gene="hydG"
                     /locus_tag="KR294_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[FeFe] hydrogenase H-cluster radical SAM
                     maturase HydG"
                     /protein_id="HBH0240716.1"
                     /translation="MFINHELINSLLEDAKNSTSDDIEKVLDKADRREKLSYKDIATL
                     LEVEDKKQLDRLFSIAGQIKNEIYGNRVVLFAPLYVSNYCVNECVYCGFSKCNKFKRK
                     KLTMEEIREEVKILEKMGHKRLALEAGEDPKNCDINYILDCLDAIYSTYNENGNIRRV
                     NVNIAATSVDEYKLLKEKGIGTYILFQETYHKPTFIKMHGQSIKNDYYYHLTAFDRAM
                     EAGVDDVGAGVLFGLSDPKFEVLGLMMHNEHLEEKFGVGFHTISFPRLKKAEGMSLED
                     FPHLVSDDMFKKIVAITRLAVPFTGIIMSTRETAEMRNELLKYGVSQISAGSLTGVGG
                     YKAYEDGDNTEQFEVGDHRSPVEVLKELITDGYIPSYCTACYRKGRTGDRFMSLAKSR
                     QIHNVCTPNALTTLNEFLIDYGDEELKIMGKKLIAEEIGKIEREDIRNIVSNNMTALE
                     RGERDLYL"
     gene            complement(5374..6459)
                     /gene="hydE"
                     /locus_tag="KR294_002652"
     CDS             complement(5374..6459)
                     /gene="hydE"
                     /locus_tag="KR294_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[FeFe] hydrogenase H-cluster radical SAM
                     maturase HydE"
                     /protein_id="HBH0240717.1"
                     /translation="MTKNKIKYFIDKLYSINSLSFDELLYLIENIDNEEYNFEQNLRN
                     YLYKQASDMRNKHYGNRVYLRGLIELTNYCKNNCYYCGIQSSNKNIIRYRLSLDEILE
                     CCDIGYKIGYRTFVLQGGEDAYFTDDKICEIVSSIKNKYEDCAITLSLGEKSYDSYKK
                     YFLCGADRYLLRHETATDSHYKKLHPPNIELRTRKECLKNLKEIGYQVGAGFMVESPF
                     QNNEDLVRDLLYLKELNPHMVGIGPFIPHHDTIFKDYKHGDLEKTLLMLSITRLLLPK
                     VLLPATTALASINPSGRNAGLLAGCNVIMPNLSPQEFRKQYSLYDNKAFTGQEACEYH
                     QSLEENIKSLGLEVDYSRGDNIEWRRL"
     gene            complement(6495..7703)
                     /gene="hydF"
                     /locus_tag="KR294_002653"
     CDS             complement(6495..7703)
                     /gene="hydF"
                     /locus_tag="KR294_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[FeFe] hydrogenase H-cluster maturation GTPase
                     HydF"
                     /protein_id="HBH0240718.1"
                     /translation="MSLNSTPQSVRVHIGLFGKRNAGKSSIINAITNQSAAIVSDIAG
                     TTTDPVFRPMEILPIGPCVLIDTAGLDDVGELGELRIGKSLDVLEKTDIALLVVDCQI
                     GISQEDLSLIEKFNDKNIPHILILNKIDTIKNQSEILNLTKNKVKCPVVSVSSTDKIG
                     IENLKNEIIKVLPKDSTEFKLVSDLIEPNDLIVLVVPIDKAAPKGRLILPQQQVIRDI
                     LDSGAISIVTKEDSLKETLSNLGKKPKLVITDSQVFPQVDKDTPKDIPLTSFSILFAR
                     QKGDLKELINGAYALENLKDGDKILMAEGCTHHRQTDDIGTVKIPNMIRKKTGKNITF
                     EFSSGVSFTEDINKYALVVHCGACMMNRAGMLSRIEKAKSFNVPIVNYGILIAYVKGI
                     LERSLELFNY"
     gene            complement(7718..7969)
                     /locus_tag="KR294_002654"
     CDS             complement(7718..7969)
                     /locus_tag="KR294_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003361768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-only hydrogenase system regulator"
                     /protein_id="HBH0240719.1"
                     /translation="MKKVAVISAILEEPKECQFKFNEVVSGFKGIIKGRMGIPCEEEG
                     VSIVCIAVVGEMDTINSLTGKLGNIPHVSVKTSISKKEV"
     gene            complement(8350..9390)
                     /locus_tag="KR294_002655"
     CDS             complement(8350..9390)
                     /locus_tag="KR294_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HBH0240720.1"
                     /translation="MNLNLTNTINLMKKYLDIPSPAGYTENAVLEIKKDFENLGLDTI
                     LTKKGALIATLPGEDDSNQITISAHMDTLGAIVKEISSDGTLKYHKVGGGCWAAIEGE
                     NCTVITRKGKKIRGSVVFKYASTHIYGQTKAATERNEETMIIRLDEKVFTKQDVLDLG
                     ISVGDFVCLDHRFEATESGFIKSRYIDNKSAVAMVLEICRYFKENNLTPKHTTNFYIS
                     NYEEIGHGVSKCLPEKTKEFVAIDIAPTGPSQTSSEHGVTIVAKDNLSLYDFNLRNKL
                     VDVAEDNNLDYAVDVFTFYGSDASEAIRWGEDVQIACVGPGTNNSHHYERTHIEAIEN
                     TLKLLINYMLKE"
     gene            9860..11020
                     /locus_tag="KR294_002656"
     CDS             9860..11020
                     /locus_tag="KR294_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF819 family protein"
                     /protein_id="HBH0240721.1"
                     /translation="MIETGFVYCSFLVVFVGVIFFMVDKLKWKVFDVINPMLLIYLGS
                     AILGSFGLFAQNEDVGTYQNIITVNFLPLMLVFLLIQCDLRKILKMGPKMLLSFFCAT
                     FTFMLGFVIAFIIFKNSMGADSWKILGAASGSWIGGSSNMIAAANALGVAEEGLSYAI
                     LMGSIGYTVWMSVCLMSVKFGPKFNKWTKCDTSFIDEVTSKLEKENKDNTAPTFVELM
                     ILLSVGFGVASFAQIVSKILPTSGILNETMWVVLVASTVSILLGMTKISKLKGSTLVG
                     NVFMYLLLAATGSKANFFGLSEAPVYIMFGLVVVLVHAISFIGLAKLFKLDLFTCEVG
                     SIANIGGVTTAPMIAGVHNPVLIPVGVLMGLLGNIIGTYCALMVTQILHMLA"
     gene            11363..11524
                     /locus_tag="KR294_002657"
     CDS             11363..11524
                     /locus_tag="KR294_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240722.1"
                     /translation="MIIPSRRIQDITLTNLKNGEVTLIELDEIYKKMGFLFVVSEGKL
                     KKIKKENHH"
     gene            11717..12346
                     /locus_tag="KR294_002658"
     CDS             11717..12346
                     /locus_tag="KR294_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HBH0240723.1"
                     /translation="MKIVTYNIHKGMDSNNRLTLTKMGLYLKQLDCDVICLQEVLYPQ
                     FLALKAVLNMGGVFATNVKKVNMIYGICTFTTSKMLNSNHFFLTSKKEQRGALCITID
                     AYGRIINVINTHLGLDRQERAKQLDEIIDYRNRLVGIVILCGDFNEKNVFLSMFNDMA
                     ISLNKSYLPTFEKSNSRIDYIFVNKNTELKGYTVEKIYLSDHYPVIGYI"
     gene            12586..13845
                     /locus_tag="KR294_002659"
     CDS             12586..13845
                     /locus_tag="KR294_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanW family protein"
                     /protein_id="HBH0240724.1"
                     /translation="MGRRTTRVSRLGKEKKRSVLIVLAALVLIMGGFTYFFNSKFLYN
                     GKIAKNVYIEGVNVSDMTKAEALKAITDKYTPEDLNLAYDGKKYTISPKDIDLKYDTE
                     DVVKDAYESTKKGSYFQNLKKYIDIRVNKANMKIKAEYDEAKLSSKVSSIADSINVKM
                     KNASISVGSGGLSYTDSVVGREFDLAANKESIYNMIKNKEHKTLELKVNLQKPDITTE
                     QVKTVNSVIGQYSTTYSQAVEGRSYNVGLSARKTSDVLLMPGEEFSYNKLTGPSNKAN
                     GYKDAPVIVYGKLEQSAGGGVCQTSSTVYNAALLSGMEITQVTNHSSASTYVPKGRDA
                     TVSDGGLNLKFKNPYKHPVYIKNYAGGGSVSSVIYGNSGDKPNISIEVKQTGQNKYST
                     YRIFKDSSGKVIKKEHISNSSYKELKK"
     gene            14104..15099
                     /locus_tag="KR294_002660"
     CDS             14104..15099
                     /locus_tag="KR294_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase"
                     /protein_id="HBH0240725.1"
                     /translation="MYEEVTWLNFIGNRYEVVNSDDVLEINKIYKARDVFYRKNVLIK
                     VIKHNNYICEDFVSNLIDESTALDEINSPYILKIIDVGIHCTEETTLYYVVSEDFNGI
                     GLDELILGNYLHLEAIVNIMIQVLKALEMIHRNHSYHGSLKSSSIIVDTEYNIKICDF
                     GITKANNGVNTRSYGNRRYLCPHQLCINYTDKESDFFATGLILFESIFKKLPFGESNS
                     EEKMLQSIDKGLDWNSIKAINGNTELINVIKRLLGRNNKYTRANDIIIDLSKVMYEKA
                     YIEVEDEKEEEQKQDKVIQVKKEYKSKMRKKLHKKLVVAGLAIVMISMIIISSII"
     gene            15345..16412
                     /locus_tag="KR294_002661"
     CDS             15345..16412
                     /locus_tag="KR294_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA ligase RtcB family protein"
                     /protein_id="HBH0240726.1"
                     /translation="MSNIKIIASNKCWIEDIARKQLEDISKLNGILRVVGLPDLHAGK
                     IPVGLAVETKNIIYPHIIGNDIGCGMTLFKTGVLKKKFKKDKWIKSLSKIKDLSDIEI
                     KNTYKEECPILNLGTIGSGNHFVEIQCISEIYNKEQFEQLKFSSDDIMMLVHCGSRNY
                     GEDILKKFYDKDGLEVESEKAIDYIKKHDNALMWAERNREAISKKIMQSIGTSGDVET
                     IFSINHNFIEKREDKFIHRKGAVSSERGAVIIPGSRGSLSYIVMPTENTEISLYSLSH
                     GAGRKWSRSVCKSRLKSKYNKDTIKQTKFKSQIICNDVNLLFQEAPEAYKNIEQIIES
                     LIEYELIQVVATMKPLITYKG"
     gene            16946..18856
                     /locus_tag="KR294_002662"
     CDS             16946..18856
                     /locus_tag="KR294_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HBH0240727.1"
                     /translation="MNSNTFERLQLNEVKELIKIHCVSSLGKNLIDKLTPSGNIGVVR
                     RKLAENKEARKIIENSNHIPLEGLFNAGSTIDKIEKGMIIEPVELVNIEDFLRGCRKM
                     KAFMLEKEFYSPTLSSYALNITECKSIEDEINYCIKSNKVDSNASKELKKIRRNIEIT
                     EGKIKDRLNKFITSTVNKKYIQEFIISKRNDRYVIPIKSSYKNEVNGTILDTSSKGNT
                     VFIEPISVSNLSTELTMLKADETIEEYKILSYLTELIFEKISQIKLNIEILSEYDMVF
                     AKAKYSQKIKGITPKINNNGYIKIIKGKHPLLTGDAVPLDFEIGKNYRSLIITGPNAG
                     GKTVTLKTVGLLTLMVQCGFDISAKEGSEFSVFEKVFVDIGDNQSIENALSTFSSHIK
                     NIAEIMSLSNNSTLVLFDEIGSGTEPNEGAGLAISLLEEFYKMGCITIASTHYGEIKK
                     FATLHPEFENAGMMFDKETLEPLYKLTIGKSEDSNALFISKKMGIKNRVLDRAKEYVI
                     DRNYNLDLVKRSKLQSNIEDKNSSEVILNYTDYNVGDKVKLLDEDDFGIVYKPMDKFN
                     NVEVLFNDNFISVNIKRLQLSIKASELYPEGYDLDVLFTSFKERKLEKDIQRGSKKAL
                     KKIQKEIRENRK"
     gene            complement(18919..19542)
                     /gene="ytaF"
                     /locus_tag="KR294_002663"
     CDS             complement(18919..19542)
                     /gene="ytaF"
                     /locus_tag="KR294_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation membrane protein YtaF"
                     /protein_id="HBH0240728.1"
                     /translation="MIESILLVTSLCIDAFVTSFGYGVNKVKVPLYSNIIISVVCSAI
                     LAISLFAGTIVRDFLPQNITMLICFFILFLLGSARLIESFFKSYFKKKSIHSKNYNFN
                     MLDLKLNFNVSIEPDVLDTSKSKVLKSAEAFTLALALSLDGLAIGFGSGLVGVNYIQV
                     ILFSLISNIIAVLLGCLLGNMFVKNVNLNLSWLSGLILLVIGFMKIC"
     gene            19730..>20302
                     /locus_tag="KR294_002664"
     CDS             19730..>20302
                     /locus_tag="KR294_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0240729.1"
                     /translation="MEQHSKVGNFGDLLKVLLDEKELSMGELSKKSGIDKSTISRIAN
                     NKQKPNINHLEKMAIHLNINLEELLKASGYEFRNSNNQIFNADSDFSNFDDILGFANL
                     INDKNFNGNIEKELSKCKLYVQTDEGKKLLFDNFNKKIDSIEKQGQFTDRLRQMYADF
                     CTDGLTIKKYLLIGSMLLYFVISTDVIPDFV"
BASE COUNT         7813 a         2382 c         3100 g         7007 t
ORIGIN      
        1 tttaatgatt ataagaataa ttttatttag agatgtacca atttacgcta ttttcaaggg
       61 aacgtttagg aatgtaaatt taattccatt ttatacaata tatcaattta tagtagatag
      121 taatcttgac tttatgaaag ctactgtaaa tattatagaa aatataggta tatttattcc
      181 tatgggaatt tttttaccta tagtatgtaa aaatctaaat aaaaaaacta taattatagt
      241 aattatactt gttagcctag catttgaatt aacacaatat atttttgctc ttggaagtag
      301 tgatatagat gatgttattt taaattcatt aggtggcata attggaatta atatttacat
      361 aaacatgaat aaattatttc ccaatgatat taacagattt aaggctataa taggtactag
      421 tttagtttta ggagttatag gattaggagt tatttctaaa aattatcata acttactaac
      481 ttttaaattt agacctgata gaaaaatatc aaaaatatta attgaagaaa atagggaaat
      541 aattaaagat ataaataaag atacagtaga tatagttggg acatttgaga gctttaaaaa
      601 aggaataata actattaaag caggttctaa taacaaagta aagagaccag agaatttaat
      661 tgattctgat ggaaatataa gaatttattt aaatgaaaat acaaaattag tatcttatat
      721 aattaccaaa gaatcaaaaa tggatatagt taaatatgag gaatttgatg tgaagaattt
      781 agatttatta aggagatatg atactattaa tgtttggatt gataaagaaa atcagccaaa
      841 ggataaacat ggtattatgg ctagtaaatt attaattgga ttgtatgaat aaaatattaa
      901 acaagaataa aagaataaca aatataaaaa acgaaaaaac tatttctata attattttta
      961 cgttgtgcat aaaataagaa cattagtgaa ggagtagaga taaattatgg agataataaa
     1021 atatatcttg tactttttta tatattcatt tttaggatgg acagtagaaa gtataggatg
     1081 ttctatagca agcaaaagaa taatcaacag aggtttttta aatggtccaa tatgccctgt
     1141 ttatggtttt ggagcggtaa ttgtgatatc actattggga agatttaata atgtagtaat
     1201 agtatttcta ttaggaatga ttttaactac gatactagaa tattttacag gatttatttt
     1261 agaaacctta tttcatgcta aatggtggga ttattctgac aaaaaattca atataaaggg
     1321 tagagtatgt ttaaaaaatg caatatactt tggtgtaatg tctgttttaa taataagatt
     1381 tatacatcca tttataaaat attttgtaag tataattcca tatagaatat taatttcaat
     1441 ggctataatt acaacacttt ggactatact tgatttgatt gttactatta taacacttaa
     1501 aaaattagat ataaagttaa acttattaga cgatataatt acagacctta atgatataaa
     1561 tgtgaaattg gataaatttg atagaggaga aatacaagct ttatttaaaa caataaataa
     1621 cgacgaatta gaagttagag aaaaaataaa caaaataaat agtaagttgg accgtataga
     1681 gtctaatatt attttacaaa aaagagttat aaaagctttt ccacatataa aacataaaaa
     1741 acaacaagag caactagaac attttaaaaa aattattaat gagaaaaggt aattatacaa
     1801 tttaatgaag acgaatagaa taatggtatt tataagatga ttttcagagg actctataaa
     1861 aatagaatag agtcctttat tttttgaaaa ataatgttta tttgataaaa ataaaatata
     1921 ttgtttctga ataacaaata ttttgaaaat tataaaaaca tatattgaca atttgtgtca
     1981 aaaatactaa cattaagtat ataaagaatt ttatatgaga atatctttat aaatcgcaat
     2041 aattttaaaa cataaattta tttaaagagg ggatgatttg ccaatgagcg agataactag
     2101 tcaaatgata agtacagaag aaaaaaaata tgttgctaaa actcaaaaga taccttatta
     2161 tccagtagca tttaaatcag gtgatggtgc aatgctatat gattatgaag gtaatgaata
     2221 tgtagatttt ttagcaagtg caggctctgc aaatgtaggt catggtaata aggaaatctc
     2281 acaagcagtt aaagaacaaa tggatgatat aacacaatat acacttgcat atttccatag
     2341 tgatcctcct gtaaaattag ctgagaagct tgtggaaata gcccctggag ataatgataa
     2401 aaaagtacta tacagtgcaa ctggttctgc ttgtatagat gctgctataa aattagcaag
     2461 agggtatact ggaagaacaa agataatatc tatgtgtgaa tcttatcatg gaagtactta
     2521 tggagctata tctatatctg ctttaagtac aaatatgaga agaaaaatgg gtccattgtt
     2581 accagaagtt tatcacttcc attatcctga taaaaataga acagctaaag aatgtttaga
     2641 tgagatagaa tatgcttttg cacactatct accagcagaa gaggtagctg caatatttat
     2701 agagccaatt gcaggagatg caggaataat agtgcctcca gtagagtggg tacaaggttt
     2761 aagtaaaata tgtaaagaaa atggaatatt acttgtaagt gatgaaatac aacaaggtat
     2821 gggaagaaca ggtaagtggt ttggtataga aaattttggt gttgaagcag accttatagt
     2881 tcttggaaaa tctgttggag gtggattacc tctaggagca gttgttggaa gaacagaaat
     2941 aatgcaaagt cttgatgcac cagcacattt atttacttta gctggaaaca caacagtatg
     3001 tgtggctgct ttaaaatcta tagagataat tgaaaaagaa aacttacttc aaaagagtat
     3061 agaaatggga gattatatta aagcaggatt tgaaaaacta aaagaaaaat acgatataat
     3121 tggagaaata agaggcatag gattatctat aggagttgat atagttaaag gaaaaggttc
     3181 taatgaaaaa catccagatg ctacagctaa gatatgttat agatgtatac aaactggatt
     3241 aataatgata ttcttaggac aatctacttt aagagtgcaa ccacctctag taataactaa
     3301 ggagcaagta gataaagcaa tgaatatcat agattctgca atagatgatt atttaaatgg
     3361 tagaattggt gatgaagtat atgaagtaac tcaaggttgg taaaataaat attaaatgaa
     3421 aataggagtt atctcaattt tagaaaatta tttctgaaaa gagataactc ttttaagtta
     3481 cccacaaata agaaaattgt ttgattcatt aaagactata tttcggatgt cgtttttgtg
     3541 agtatcagag acagtattac gagaataatt acctttattc gtactatctg ttaatttagt
     3601 tataattaag atagctaaaa gaataagaat tactgtgtat aaagcaataa catatggttt
     3661 tcttttatat ttgtatttgt tattgaaaaa agaatggcca taattatttt tatttacttt
     3721 agatgtattt gtattctttt tcttgttacc tttcttttta tcatcctttt ttctattttt
     3781 agggtaagga atgactttgt gtgtattatc aagtttgata tttttatttt tttgaatatt
     3841 gttttccagg ctagcttttt tttctccaaa ttgaatagtt ttattggtat tgttgttatc
     3901 tttcaatgtt aatctccctc ccttaaactt tccctttaga taatattact actaacctat
     3961 ggaatataca ataaataata tataagtaat aaaattttat aggtataaat ctctttctcc
     4021 acgctctaag gcagtcatat tgttagatac tatgtttctt atatcttctc tttctatctt
     4081 acctatttct tctgcgataa gttttttacc cataatttta agttcttcat ctccataatc
     4141 gattaaaaat tcatttaatg tagtaagagc atttggtgta catacattat ggatttgtcg
     4201 acttttagct aagctcatga atctatcgcc agttctacct ttacgataac aagctgtaca
     4261 ataactaggt atatatccat cagtaatcag ttctttaagc acctcaacag ggcttctatg
     4321 gtctccaact tcgaattgtt ctgtattgtc accatcttca tatgctttat atcctccaac
     4381 acctgttaga gaacctgcac taatttgtga tacaccatat tttagtaact catttctcat
     4441 ttcagcagtt tctctagtgg acattatgat tccagtaaaa ggaacagcta atctagttat
     4501 agctactatt tttttgaaca tatcgtcaga aactaagtga ggaaaatctt ctaagctcat
     4561 accttcagct tttttcaatc tagggaaaga tatagtatgg aaacctacac caaatttttc
     4621 ctctaagtgt tcgttgtgca tcataagtcc tagaacttca aatttagggt cagataaacc
     4681 aaataaaact cctgcaccaa catcatcaac accagcttcc atagctctat caaaagctgt
     4741 taaatggtaa taatagtcat tttttataga ttgaccatgc atttttataa atgttggttt
     4801 gtgataagtt tcttggaata atatataagt tcctattcct ttttctttta gtaatttata
     4861 ctcatctaca cttgtagctg ctatgttaac gtttaccctt cttatatttc cgttttcatt
     4921 atatgttgaa taaattgcat ctaagcaatc taagatgtaa tttatatcac aatttttagg
     4981 gtcttcacca gcttctagag caagtctttt atgacccatt ttttctaata ttttaacctc
     5041 ttcccttatc tcttccatgg taagtttttt tcttttaaat ttgttgcatt tactaaaacc
     5101 gcaataaaca cattcattta cacagtagtt tgatacataa agaggggcaa ataaaaccac
     5161 tctattacca tatatttcat tttttatttg cccagctata ctaaataatc tatctagttg
     5221 ttttttatct tctacttcaa gaagtgtagc tatatcttta taactaagtt tttcccttct
     5281 atcagcctta tcaagtacct tttcaatatc atcagaagtt gaattttttg catcttctaa
     5341 taaagaatta ataagttcat ggtttatgaa catttacaaa cgcctccatt caatattatc
     5401 accgcgagaa tagtcaactt caagtcctaa tgacttgatg ttttcttcta aactttggtg
     5461 atattcacaa gcttcttgac cagtaaaggc tttgttatcg taaagagaat attgttttct
     5521 aaattcttga ggagaaaggt ttggcataat tacattgcaa ccagctaaaa gacctgcatt
     5581 tctaccacta gggtttatag atgccaaggc tgttgtagcg ggtaataaaa cttttggaag
     5641 tagaagtctt gtaattgaaa gcataagtaa tgtcttctct aaatctccat gtttataatc
     5701 cttaaaaatt gtatcatggt gtggaatgaa aggtcctatt ccaaccatat gaggatttaa
     5761 ctcttttagg tataataaat cacgaacaag gtcttcgttg ttctgaaatg gtgattcaac
     5821 cataaatcca gcacctacct gataaccaat ttctttaagg ttttttaggc attcttttct
     5881 agttctaagc tcaatgtttg gcggatgtaa ttttttataa tgactgtctg tagcagtttc
     5941 atgtcttaaa agatatctat ctgcaccaca taaaaagtat tttttatacg aatcataact
     6001 cttttctcct agtgatagag ttatggcaca atcctcatat ttatttttta tacttgaaac
     6061 aatttcacat attttatcat cagtaaaata tgcatcttca ccaccttgca aaacgaatgt
     6121 tctgtatcct attttataac ctatatcaca acattcaagt atttcatcaa gtgaaagcct
     6181 gtatcttatg atatttttat tagaagattg tattccacaa tagtagcaat tatttttaca
     6241 atagtttgta agctctataa gtcctctcaa gtagactcta tttccataat gtttatttct
     6301 catgtcgcta gcttgtttat aaagatagtt tcttaaattt tgttcgaagt tatattcctc
     6361 attgtcgata ttttctatta aatatagtag ttcatcaaaa cttaatgaat taatgctgta
     6421 aagtttatct ataaagtatt taatcttatt tttagtcata ttcaaatata taattattaa
     6481 gtatagttaa atttttaata attgaaaagt tcaagtgatc tttccaaaat accttttaca
     6541 tatgctatta agataccata gtttacaata ggtacattga aagattttgc cttttctatt
     6601 ctagataaca ttccagctct attcatcata caagctccac agtgaactac aagggcatat
     6661 ttatttatat cttcagtgaa ggatactcca gaactaaatt caaaagtaat gtttttgcca
     6721 gttttctttc taatcatatt aggaattttt actgttccaa tatcatcagt ttgtctatga
     6781 tgggtacatc cttcggccat caagatttta tcaccatctt ttaaattttc taaagcataa
     6841 gcgccattaa tcaattcttt aaggtctccc ttttgtctag caaacaatat agaaaaagat
     6901 gtaagaggaa tatcttttgg tgtatcttta tctacttgtg gaaatacttg agagtcagta
     6961 ataacaagtt ttggtttttt gcctaaatta gatagagttt cttttaaact atcttctttt
     7021 gtaactatag aaattgcacc actatccaaa atatctctta taacttgctg ttgaggaagt
     7081 ataagtctac cttttggagc tgctttatct attggaacaa ctaaaacaat taaatcattt
     7141 ggttcaatta aatctgatac caatttgaac tcagtgctat ccttaggcaa aacttttatt
     7201 atttcatttt ttaaattttc aattccaatt ttatctgttg atgagacaga aacaactgga
     7261 catttaactt tatttttagt taagtttaaa atttctgatt gattcttaat agtatcaatt
     7321 ttgttgagaa ttagaatatg agggatattc ttatcattaa acttttcaat tagtgacaaa
     7381 tcttcttgtg atataccaat ctggcaatcc actactagta aagctatgtc tgtcttttct
     7441 aaaacatcta gtgatttacc tattctaagt tcaccaagtt caccaacatc atcaagacca
     7501 gcagtatcta taagaacaca aggtcctata ggaaggattt ccattggtct aaatactggg
     7561 tctgtagtag ttccagcaat atctgagact attgcagcac tttgatttgt tatagcattt
     7621 attatgctag atttacctgc atttctttta ccaaagagac ctatatgtac tcttaccgat
     7681 tgtggagtag aatttagact catttgtact caccacctta aacttctttt tttgatatac
     7741 tagtttttac agatacatga ggtatgttgc ccaatttacc agtcaaacta ttaatagtat
     7801 ccatttcgcc aacaactgct atacatacga ttgagacacc ttcttcttcg caaggaatgc
     7861 ccattcttcc tttaataata cctttaaaac ctgatacaac ctcattgaat ttaaattgac
     7921 attcttttgg ctcttccaaa atagcactta taactgcaac ctttttcata aatatcctcc
     7981 taactcagaa aatatgtctt aaacaaatcc aaaatcaaaa aacttttctt tgtaaagaaa
     8041 agtttctaca aaagaaaagt tattaattac acaagtataa tgtgctatat taaactattt
     8101 ccttacagat tagataactc ttttctggta gggttagctt gtaaaaattt aatttaacaa
     8161 caagtaactg aagaaaattt ttatacaatt tatataaatt ataataaaaa ttaactaaag
     8221 aaaattgaag ttacttatat aatagtagta aattgaaatt aagtctatag aaaaaccaat
     8281 ttttgtataa aaataaaaat taaagttaat tatttgttaa gaattgactt tggtaaaata
     8341 tataattaat tattctttaa gcatataatt tataagtaat tttagtgtat tttcaatagc
     8401 ttctatatgt gttctttcat aatggtgact attgtttgtt ccaggaccaa cacatgctat
     8461 ttgaacatct tctccccaac gaatagcttc tgaagcatct gaaccataga aagtaaatac
     8521 atcgacagcg tagtctaaat tattgtcttc tgcaacatca acaagcttgt ttcttaaatt
     8581 aaaatcatat aatgataaat tatcttttgc aactatagtt acaccatgtt cactagatgt
     8641 ttgacttggt ccagtaggtg ctatatctat tgctacaaat tcttttgttt tttcaggtaa
     8701 acatttagaa acaccatgtc caatttcttc ataattactt atataaaagt tagtagtatg
     8761 cttaggtgtt aaattgtttt ctttaaaata tctacatatt tcaagaacca ttgctacagc
     8821 tgatttatta tctatatatc tagattttat aaaaccagat tctgtagcct caaatctatg
     8881 gtctaggcat acaaaatccc caacacttat tcctaaatct aatacatctt gctttgtaaa
     8941 tactttttca tcaagtctaa taatcattgt ttcttcattt ctttcagtgg cagcttttgt
     9001 ttgaccatat atatgagtag aagcatactt aaatacaaca cttcctctga tttttttacc
     9061 ttttctagtt ataacagtac agttttctcc ctctatagct gcccaacatc caccaccaac
     9121 tttatggtat ttaagagtac catcagatga tatttctttt actatagctc caagtgtatc
     9181 catatgtgca gatattgtta tttgatttga atcatcttca ccaggaagag tagctataag
     9241 tgcacctttt tttgtaagaa tagtgtcaag acctaaattt tcaaaatctt ttttgatttc
     9301 taaaactgca ttttcagtat atccagctgg gcttggaatg tccaaatatt ttttcattaa
     9361 atttatagta ttagttaaat ttaaattcat attgtttcct cctaaataaa tatatttata
     9421 caaattataa cataaataca aatgttctga aaactaaaat taaaagaata gaatctaaac
     9481 atatttaaaa aaaaagtata taaaataaat ttgatttata ttatatagat ttaaagtaaa
     9541 aatagtttta tttaataatt aataaaaata aatacaaaac aaaataaata aataataaaa
     9601 tatttagttt aattatcttt acaaataaaa attttagtaa taaaataatt gttgaaaaag
     9661 attttaaatt cagattattc atttctaaag taattaatgt gcaaatcttt attaatatat
     9721 gtcaatagtt aggtatatat gtatttaatt agcatgatat agataaaagt atttatttta
     9781 attgtctatt atctgaaaaa gtctttactt agaaatcata aaaatcaaat taattaggaa
     9841 aagaaagggt gtgtataatg tgattgagac tggatttgta tattgtagtt tcttggttgt
     9901 attcgtaggt gtaatttttt ttatggttga taaattgaaa tggaaggtat ttgatgttat
     9961 taatccaatg cttttaatat acttaggttc agctatactt ggatcatttg gtttatttgc
    10021 acagaatgaa gatgttggaa cgtatcaaaa cataataaca gtgaacttcc ttccattaat
    10081 gttagtgttt ttgttaattc aatgtgattt aagaaaaata ttaaagatgg ggcctaaaat
    10141 gttattatca tttttctgtg ctacatttac atttatgctt ggatttgtta tagcattcat
    10201 aatttttaaa aattcaatgg gtgcagattc atggaaaatt cttggggcag catctggttc
    10261 atggataggt ggctcatcaa atatgattgc agcagctaat gctctaggag ttgcagaaga
    10321 aggacttagt tatgcaatac ttatgggttc tataggatat acagtatgga tgtctgtttg
    10381 tctaatgtct gtgaaatttg gacctaaatt taacaaatgg acaaagtgcg atacaagttt
    10441 tatagatgag gttacatcaa aacttgaaaa agaaaataaa gataatacag cacctacgtt
    10501 tgtagaactt atgattttac tttctgttgg gtttggagtt gcgtcttttg cacaaattgt
    10561 atccaagata cttccaactt caggtatact taatgaaact atgtgggtag tacttgttgc
    10621 atctacagta tcaatattat tgggtatgac aaaaatatca aagcttaaag ggagtacact
    10681 ggtaggaaat gtgtttatgt atttactcct tgcagctaca ggtagtaaag caaatttctt
    10741 tggattgtca gaagcacctg tttacataat gtttggattg gtagtagtcc ttgtacatgc
    10801 tatttcattt atagggcttg ctaaactatt taaacttgat ttatttactt gtgaagtagg
    10861 aagtatagct aatataggag gagtaactac agctccaatg attgctgggg ttcacaatcc
    10921 tgtattaata ccagtaggtg tacttatggg gcttctagga aatattatag ggacttattg
    10981 tgctcttatg gtaactcaaa tattacatat gttagcttaa tgaaaatatg gtataaaatt
    11041 aataatttaa ataagaaaag tcatttcaat ttaagcagaa gcttttactg aaatggcttt
    11101 ttttgtttga caagataatc tatttcaaga agatgttttg acatatttag tgtataatat
    11161 tgtaaaattt actaaaaacg agatatattt aatttttata ttgaatcgaa cgtctgtatg
    11221 atgtataata aatatacaga acgaatgttt gcggaacggg tgttttttga atttatttta
    11281 ataatttatg aatatatatc agaatgcata aatatattta aatataaaga ttaaaaagaa
    11341 tttaaaggag tgttgataac ttatgataat tccatcaaga agaatacaag atataacatt
    11401 aacaaattta aaaaatggtg aagtaacttt aattgaattg gatgaaatat acaagaagat
    11461 gggattttta tttgttgtta gtgaaggcaa attgaaaaag ataaaaaagg agaatcatca
    11521 ttagaaatga atgaaataat aaatattata atagtttata aaacctaact tatgtagaat
    11581 ataaatactt aagttaggtt tttttgtgat aaagtttata agtactcaat tttataagat
    11641 aaataatggt tttaagtgaa aagtaaataa gtttaaattt tagtaagtat tatattgcat
    11701 aagaggtgat attattatga aaatagtaac ctacaatatt cataaaggta tggattcaaa
    11761 taatagatta actctaacta aaatggggtt atatttaaaa caattggatt gtgatgtaat
    11821 ttgtttgcaa gaagtattat atcctcaatt tttagcttta aaagctgttt taaatatggg
    11881 tggtgtcttt gctacaaatg taaaaaaagt aaatatgata tatggtattt gtacatttac
    11941 aacatctaaa atgttaaaca gtaatcattt tttcttaact agcaaaaaag aacaacgggg
    12001 agctctttgt ataactatag atgcatatgg aagaattata aatgtaataa atactcactt
    12061 gggacttgat aggcaggaga gagcaaaaca attagacgaa ataatagact ataggaacag
    12121 attagtgggg atagttattt tatgtggtga ttttaatgag aaaaatgtct ttttaagtat
    12181 gtttaatgat atggctattt cactaaacaa gtcttactta ccaacatttg aaaaatcaaa
    12241 ctctagaata gattacattt ttgttaataa aaatactgaa ctaaaaggat acacagtaga
    12301 aaaaatttac ctgtcagacc attatcctgt aataggttac atttaaattt caatataaat
    12361 gaaattagtt gttataaaat aaacaatttt tttgttaaga aatagtaaaa gaaatataat
    12421 aaaaaatatc aaaaataaaa ctaattataa gacataaatt tacaataaag ttacatttga
    12481 ttaaattcct tgtttaacaa aagctattca aatataatct aaggtagttt tgaaatggga
    12541 actctattat gcaaatttaa gctagtgtta aaatgaggtg aagttatggg cagaagaaca
    12601 acaagagttt caagattagg taaagaaaaa aaacgaagtg ttttaattgt attggcagct
    12661 ttagttctaa taatgggtgg atttacttat ttttttaaca gtaaatttct gtacaatggg
    12721 aaaatcgcta aaaatgtata tatagaagga gtaaatgtat ctgatatgac taaagcagag
    12781 gcattaaaag ctataacaga taagtatact ccagaagact taaatcttgc ttatgatggg
    12841 aaaaaatata caatatcacc aaaagatatt gatttaaaat atgatacaga agatgttgta
    12901 aaagatgctt atgaaagtac aaaaaaaggg tcctattttc aaaacttaaa aaaatatatt
    12961 gatataagag tgaataaggc aaatatgaag ataaaagctg aatatgatga ggcaaaactt
    13021 agttccaaag tgtcttctat agcagatagt ataaatgtta agatgaaaaa tgcttctatt
    13081 agtgttggaa gtggtggact aagttataca gactctgttg taggtagaga atttgatttg
    13141 gcagcaaata aagagtctat atataatatg ataaaaaata aagagcataa aactttagaa
    13201 cttaaagtaa atcttcaaaa accagatata acaactgaac aagtaaaaac tgtaaattct
    13261 gttataggtc aatattcaac tacttattca caagctgtag agggtaggtc atataatgta
    13321 ggattatcag caagaaaaac tagtgatgta ttattaatgc caggtgaaga attttcatac
    13381 aataaactta caggacctag taataaagca aatggttaca aagatgcacc tgttatagtt
    13441 tatggtaagc tagaacaatc agcaggagga ggtgtttgtc aaacatcttc aacagtttat
    13501 aatgctgctc ttctttcggg tatggagata actcaagtta caaatcattc atctgcatct
    13561 acttatgtgc ctaaagggag agatgctact gtgagcgatg gaggattaaa cttaaagttt
    13621 aaaaatccat ataagcatcc tgtatatatt aaaaattatg caggtggagg aagtgtatca
    13681 tcagtaatct atggtaattc tggtgacaaa ccaaatatat ctatagaggt aaaacaaact
    13741 ggtcagaata aatattctac atatcgaata tttaaagatt caagtggaaa ggtcataaaa
    13801 aaagaacata tatcaaatag ttcttataaa gaattaaaaa aatagataat tttttagaga
    13861 aatatttgta atataaaagg gagtgtctca aaatgaactt tttagtttat gaggcactct
    13921 ttttctgtga aatcaaatat attttcatca tttcaacaat acaaaagaag cgtatctcta
    13981 ttttgagaca gccttttttg taaaaattaa cactattagt tcttgtttta atattacaat
    14041 cattaatata tagaaaatat tcctatatat tggtataatt gtaaatagat ttagttatat
    14101 aaaatgtatg aggaggtgac atggttgaat tttataggca atagatatga ggtagtaaat
    14161 tctgatgacg ttttagaaat taacaaaatc tataaagcta gagatgtttt ttacaggaaa
    14221 aatgtgttaa taaaagttat aaagcacaat aattatatct gtgaagattt tgtttcaaat
    14281 ttaattgatg aaagtactgc tttagatgag ataaactctc cttatatact aaaaataata
    14341 gatgttggga ttcactgtac agaagaaaca acattatatt atgttgtaag tgaagacttt
    14401 aatggtatcg gactagatga attaattcta ggtaattatc ttcatttaga agcaattgta
    14461 aacataatga tacaagtttt aaaagcttta gaaatgatac ataggaatca ttcatatcat
    14521 ggtagtttaa aatcgagtag tataatagta gatacagaat acaatataaa aatttgtgat
    14581 tttggaatta caaaagcaaa taatggggtt aatacaagaa gctatggaaa caggagatat
    14641 ttatgcccac atcaactatg tataaattat actgataaag aaagtgattt ttttgcaaca
    14701 ggtcttattc tatttgaatc tatatttaaa aaattgcctt ttggagaatc aaattcagaa
    14761 gaaaaaatgc tacaatctat tgataaggga ttagattgga atagtataaa agcaattaat
    14821 ggaaatactg aacttataaa tgttataaaa aggcttcttg gaagaaataa taagtatact
    14881 agagccaatg atattattat tgatttaagt aaagtaatgt atgaaaaagc atatatagaa
    14941 gttgaagatg agaaagaaga agagcagaaa caagacaaag ttatacaagt taaaaaagaa
    15001 tataaaagta aaatgagaaa aaaattacat aaaaaacttg ttgttgccgg tctagctata
    15061 gtcatgattt caatgattat tattagttcc ataatataaa aattgtatat taagtatttt
    15121 aaaatcaatg tctataaagg atatacatag aaattttagt gtagtcttaa attatgaaag
    15181 gaagtggtta ttatgttaac aaaaaataat gaggtattaa acgtctagga gtattttaac
    15241 aaatagccac ctgcttttac agtttagaat aaaaaagctg tggctaaagg tcacagcttt
    15301 ttgctacttt ttaaaggcag gagaatatta aaaaggagca aattatgagc aatataaaaa
    15361 taatagcaag taataaatgt tggattgaag atatagcaag gaaacaactt gaagatattt
    15421 caaagttaaa tggaatttta agagtagtag gattacctga cttacatgca ggtaaaatac
    15481 ctgtaggttt agcagttgag actaaaaata ttatttatcc acatataatt ggaaatgata
    15541 taggatgcgg aatgacttta tttaaaactg gggttctaaa aaagaaattt aaaaaagaca
    15601 aatggattaa gtcacttagt aagattaaag atttgtccga tatagaaata aaaaacacat
    15661 ataaagaaga atgtccaatt ttaaatttag gaactatagg gagtggaaat cattttgtag
    15721 aaattcaatg tataagtgaa atttataata aagaacaatt tgaacaatta aaattttcat
    15781 ctgatgatat tatgatgtta gttcactgtg ggtcaagaaa ttatggagaa gatattttaa
    15841 aaaaatttta tgataaagat ggacttgaag ttgaaagtga gaaagctata gattatatta
    15901 aaaaacatga taatgcttta atgtgggcag agcgtaatcg tgaagctatc agtaaaaaaa
    15961 ttatgcagtc aataggtaca tctggagatg ttgaaacaat attctctata aatcataatt
    16021 ttatagagaa aagggaagat aaatttatac atagaaaagg tgctgtttca agtgaaagag
    16081 gagctgtgat tataccaggt tcaagaggca gtctatcata tatagttatg cctactgaaa
    16141 atacagagat atctttatat tctctatcac atggagcagg tagaaaatgg tctcgttcag
    16201 tttgtaaatc tcgccttaaa agtaagtata ataaagatac tataaaacaa actaaattta
    16261 aaagtcagat tatatgtaat gatgtaaatt tattatttca agaagctcca gaggcatata
    16321 agaatataga gcagattatt gaaagtttga tagaatatga acttattcaa gtagtggcaa
    16381 ctatgaagcc attgattact tataaaggat aatttttaaa gttaaaaaag attaaaatta
    16441 tattataaat agctaatttt atggaacatt taaaagtgtt ttattattag ctattttttt
    16501 attttgtaga gacgataatt tatagagcta aattctttga tatataatga ttacaaagtt
    16561 agactgtatt ggaaaatgca catacatgaa ttgatgacaa tataagtgat tcccaaatat
    16621 aaatgaaagt ataagcttat tttcactata aaaattttca ctgtacaaaa acattaatga
    16681 cattattttt attgacataa atatataatt tatggaataa tattagaagc actgatataa
    16741 gtgtttaaat aagaatagaa aaggagaagt gttttatgaa aaaaaatact aacattaatg
    16801 agtccggagt taaacttctt aataaataag gagtttgata tataataact ccttatttat
    16861 taagttgttc gcaaaataac tattatcaaa gtaaatgata gggtgattta aaagacgata
    16921 acttataaat aaaggagaaa aaataatgaa tagtaataca tttgaaagat tacaactaaa
    16981 tgaagttaaa gaattaataa aaatacattg tgtaagttca ctaggaaaaa atttaataga
    17041 taaattaact cctagtggga atattggagt agtaagaagg aaattagcag aaaataaaga
    17101 agctagaaag ataattgaaa atagtaatca cataccactt gaaggattgt ttaatgcagg
    17161 ttctacaata gataaaattg aaaaaggaat gataatagaa cctgttgaac ttgtaaatat
    17221 tgaagatttt ttaagaggtt gtaggaagat gaaagctttt atgttagaaa aagaatttta
    17281 ttcacctaca ttaagttctt atgccttaaa tataacagaa tgtaaaagta tagaagatga
    17341 gataaattac tgtataaaat ctaataaagt tgattctaat gctagtaaag aattaaaaaa
    17401 gataagacga aatatagaaa ttacagaagg aaagataaaa gatagattaa ataaatttat
    17461 aacatcaact gtaaataaaa agtatataca agagtttata ataagtaaaa gaaatgatag
    17521 atatgtaata ccaattaaat cttcttataa aaatgaagtt aatggtacta tattagatac
    17581 atcatcaaaa ggaaatacgg tatttattga acctattagt gtttcaaatt taagtacaga
    17641 gttaactatg ttaaaagctg atgaaactat tgaagaatac aaaatattat cttatttaac
    17701 agaacttata tttgagaaga taagtcagat aaaattaaat atagagatac tttcagaata
    17761 cgatatggta tttgcaaaag ctaagtatag tcaaaaaata aaaggaatta ctccaaaaat
    17821 aaataataat ggctatataa aaataattaa aggtaaacat ccacttctaa caggagatgc
    17881 agtaccttta gattttgaaa taggcaaaaa ttatagaagt cttataataa caggtcctaa
    17941 tgcaggagga aaaactgtaa cccttaagac tgttggttta ctaactttaa tggttcaatg
    18001 tggatttgat atttctgcaa aagaaggtag tgaatttagt gtatttgaaa aagtttttgt
    18061 agatataggg gataatcaaa gtattgaaaa tgccttaagt actttttcat cacatataaa
    18121 aaatattgca gagattatga gtttatcaaa taattctact cttgttctgt ttgatgaaat
    18181 aggaagtgga actgaaccta atgaaggagc tggtttagca atatcattat tagaagagtt
    18241 ttacaaaatg ggatgtataa ctatagcatc aactcattat ggagagataa aaaagtttgc
    18301 tacattgcat ccagaatttg aaaatgctgg tatgatgttt gataaagaaa cgttagaacc
    18361 attgtataag ttaactattg gaaaatctga agatagtaat gctcttttta tttctaaaaa
    18421 aatgggaata aaaaatagag ttttagatag agctaaagaa tatgtaattg atagaaacta
    18481 caatttagat ttagttaaaa gaagtaagct acaatctaat attgaagata aaaatagttc
    18541 tgaagtcatt ttaaactata cagattataa tgtaggggat aaggtaaaat tactagatga
    18601 agatgatttt ggaattgtat ataagcctat ggacaagttt aataatgtag aagtattgtt
    18661 taatgataat tttatttcag taaatataaa aagattacaa cttagcataa aagcatcaga
    18721 attgtatcca gaagggtatg atttagatgt attatttact agttttaaag aaagaaaatt
    18781 agaaaaagat attcaaagag gttcaaaaaa agctcttaaa aagattcaga aagaaattag
    18841 agagaataga aaataaatat aaaaagcaca aaagaaagca atctaaagag aaaagtttat
    18901 ctttagattg ctttcttatt aacatatctt cataaatcca atgactaaca agattaaacc
    18961 acttaaccaa gataagttta aatttacgtt tttaacaaac atatttccta gtaaacaacc
    19021 aagtaatact gcaattatat ttgatattaa agaaaataga ataacttgta tataattcac
    19081 acctacaagg ccactaccaa aaccgatagc taatccatct aaacttaaag caagtgcaag
    19141 tgtaaatgct tcagcagatt taagcacttt agatttactt gtatctaaga catcaggttc
    19201 aatacttaca ttaaaattta atttaaggtc taacatatta aaattataat tctttgagtg
    19261 tatagatttt ttcttaaaat aagatttaaa aaaactttca attagtctag cacttcctaa
    19321 taaaaataaa ataaagaaac atattaacat tgttatattt tgaggtaaaa agtctctaac
    19381 tattgtacct gcaaaaagcg atattgctaa aatagctgaa caaactacgc tgataattat
    19441 atttgaatat aagggaactt taactttatt tacgccatat ccaaagcttg tcacaaaggc
    19501 atctatacaa agagaagtaa ctaataaaat tgattcaatc acagtagatt aacatccttt
    19561 ctcttaaatt ttgtacttat attagttata gtattgtaaa aatggataaa ttgttacaga
    19621 taatccaata aattgttgat aaaattccaa catcatacaa cacctaaata acaaaagaat
    19681 catatcatat aataatataa aaccaatcat aataaagcag gtgaaaataa tggaacaaca
    19741 tagtaaggtt gggaatttcg gtgatttgtt gaaagtttta ttagatgaaa aagaattatc
    19801 aatgggagaa ctaagtaaaa aaagtggaat tgataaatct actatatctc gtatagctaa
    19861 taataaacaa aagccaaata taaatcattt agaaaagatg gcaatacatt taaatattaa
    19921 cctagaagaa ctgttgaaag cttcaggata tgaatttaga aacagcaata atcaaatatt
    19981 taatgcagat agtgatttta gtaactttga tgatattctt ggatttgcaa atttaatcaa
    20041 tgataagaac tttaatggaa atattgaaaa agagttaagt aagtgtaagt tatatgtcca
    20101 aacagatgaa ggtaaaaaat tactttttga taattttaat aaaaaaatag attctattga
    20161 aaaacaaggt caatttacag atagattaag acaaatgtat gctgattttt gtacagatgg
    20221 acttacaata aagaaatatt tattgattgg aagtatgcta ctttactttg ttatatcaac
    20281 agatgtgatt ccagacttcg tg
//
LOCUS       DAEPKC010000074        19849 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.074, whole genome shotgun sequence.
ACCESSION   DAEPKC010000074 DAEPKC010000000
VERSION     DAEPKC010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 19849)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19849)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19849
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.074"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            339..1742
                     /locus_tag="KR294_002665"
     CDS             339..1742
                     /locus_tag="KR294_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBH0240730.1"
                     /translation="MKMLNNFFKKINNPAPVFAQTKMERDNQTDDSLSTKPKTTFRDV
                     AGLDEVKEELFEIVDFMKSPQKYQKMGAKIPKGVLFYGPPGTGKTLLASAVAGETNSS
                     FFNVTGSEFVEKYVGVGAKRVRTLFEKARKEAPSIIFIDEIDAVGAKRHLESNNEKDQ
                     TLNQLLVEMDGFNKDSNVLIIGATNRLDLLDEALLRPGRFDRHIHIGAPNYHTRFEIL
                     KVHTDDKPIDKSVNLELLAKKTHGFNGAHLSNIANEAAIFAVRDDSECITSEHFDKAL
                     ERVIAGLESKNSALVEKEKKIVAYHEAGHALVSDIVGICPIQKISIVPRGQALGYVLQ
                     LPDEDRYIYTKDELIGKIKILLAGKASEELIFNHKSTGAKDDLKKVTEIANQMVCEYG
                     MSNLGFMTIDGNDKTFLCDKVQKEANRIVEICYKETLEMLKDNLEDLHSVSKFLFEKE
                     TMTHEELKDLIGKEAVN"
     gene            complement(2162..3184)
                     /locus_tag="KR294_002666"
     CDS             complement(2162..3184)
                     /locus_tag="KR294_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBH0240731.1"
                     /translation="MNQKKVHYNKSATSKDVARLAGVSQSSVSRAFGSANGKGVKPEV
                     RERIFRVANEIGYVPNLVARGMISGKTNVIGLIVGDSLGPFYNRIINLFVEKIQEIGK
                     QCLVFKVPRQQSIDSIISKVIQFQVEAVIITASAMNKVMAETCEENNIPVILFNRFIP
                     GIKISTVYVDPIEGGGMAAEYLLKKGHKNIGYIQFTRETSEEMEKKIGFYSKLRQSGI
                     HNLKEESANYDYDSGYEAGKRMLALSNPPTAIFCTSDLIAIGVMDAARFEYKLRVPED
                     LSVIGYDDIQMASWKSYNLTTIRQPLDLLIEKTINILKSLLNEENPESVVEMLKPELI
                     ERGSTL"
     gene            complement(3219..4817)
                     /locus_tag="KR294_002667"
     CDS             complement(3219..4817)
                     /locus_tag="KR294_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
                     /protein_id="HBH0240732.1"
                     /translation="MISSIDVCIIIGYLLLMLVIGYYSGKDNKNQEDYFLAGRSMPWI
                     PIALSVAATMISANGFIGGPGWAYVDGMYPVMVNITVPLAIFFALSITTPVIYKLKIT
                     SIYEYMGLRLGNYSRGLTIIQFFINSLIQASSMVYIPVLIIQMITGWSLYALVPIVVL
                     VSIIYTLLGGIKAVIWTDSIQMIVVISAVFIVIIVALKGMNLSFFDTLQIAQQSGKLN
                     TFDFSRDISVTNTFWATLIGGTVMWIRYFCFDQSQVQRVLTSKSLKCAKNSFVVSAFV
                     MNLVYYFMLLVGVILFVFYGGRTFETSNEIMITFILNELPVGAIGIIIAGVFAAAMSS
                     IDSILNSMTTVFTKDIYEFYFKKDNKESSLKVTMIITVVIGVVMTGFIIMGFGGSIKS
                     ILDLVGNYISYFAGPATGAFVLAMFTYKANDKGVSIGFIVGLVLGFFISNKYNVSWLW
                     NPAIGATITLIFGYIFSVILKKNHNADDIKKYTAFGMRNHLISQGMDKVDGVSIVPFS
                     LGKQELIVLAFFIIQYIILFLIQF"
     gene            complement(4859..6124)
                     /locus_tag="KR294_002668"
     CDS             complement(4859..6124)
                     /locus_tag="KR294_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH0240733.1"
                     /translation="MKTTVEIENDIILGKDYSNLKRGIAFFSIALIYFFYCYNFMVGT
                     FIKPTMIYALADGGFGFSLKQTEEIFAVMSFGTIPGTFIFGVISTKIGKKRTLISVAL
                     LIGLTTFIPMLSPTNIMLWKIARLCTGVVLGGVFGTAMPLVADMFPSKYRGKLAAILT
                     ALFSLAMIFGGKVYGVLGDANWQILMYTAIIPPIVGAILAIFFVPDDLEYTKELVKKG
                     KETGEKISYISMYKGKYLWIGLGTILLSGANFTAYSAFSNNATTYLVTGIGMSAAVAG
                     SIYSLQGIGQLVGYLFWGSIADKFGRKIPFIGMALAAVFVFIYTKLGGDNTTTFYMIS
                     VLLGVAVGYSGAWGAYYTELFPSKYRSLSSGMSFNGGRIISTFAIPAIAGTASGTLGM
                     MTIFYISIAVFVAGAIVWLFLPETLNNKK"
     gene            complement(6268..7695)
                     /locus_tag="KR294_002669"
     CDS             complement(6268..7695)
                     /locus_tag="KR294_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ester cyclase"
                     /protein_id="HBH0240734.1"
                     /translation="MASTNKNNATSKEEEKEVSTSGLESCTVKENKAKMNQTNFSNIN
                     ENQTNENKTNTYKRNIDKGNIDKGNIDKTNTNKSDINKVNIDTVDTDKLNTNTLTEKN
                     KKIIFKGEDNMSSTKIYYGDSLEVTPVGVMDYNDFSKQTKREQEIPGFDSKYRDFVDY
                     IMKITHNIWEEKGIGVIYDTYHNNVTMHCGSSNLVGIKDVISNTLQTLHAFPDRRLIG
                     QNVIWSNFGADGFLSSHRVLSTATNLGDSNFGPATGRKINFRTVIDCATTNNRIHEEW
                     LVRDNLWIVTQLGLNPQEVAKSMAKASESKVLSLQSTYGICESMDGQFMPTKYQAKDD
                     SVGEMMLEMTSRIYNYKYINEVKKYYHDNAVVHFICDKDLNGYDEIQGMIVSLLASIP
                     NGSYEVERVTCNQREKNEGYDVSVRWRLRGINEGIGFFGQPSGKHIEVMGINHYHILQ
                     GKVKEEWITFDGMDVLKQMYMGVEE"
     gene            complement(7733..8740)
                     /locus_tag="KR294_002670"
     CDS             complement(7733..8740)
                     /locus_tag="KR294_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HBH0240735.1"
                     /translation="MGKYQDSKKVVRNYFEALENATGDEVENVLKQHMKSDYNWKGVY
                     PFREQEGTENVADVFWKPLKKSLSNMQRRQDIFIAGTNEIDNSEWVMSMGHFMGLFDK
                     DWLGIKHTRKMISLRYAEFNCVQDGKIAKTGLFVDIIGFMIQAGVNPLPPQTGSYFVY
                     PGPIDHNGLLFEDADEVEGVKTLALVNKMVDDLSELNESGAMGCPPEILEKSWAKDMI
                     WYGPGGIGASYTIPRYQEQHQLPFRNNLKGKTFNGHVCRFAEGNFACFFGWPNLTNVP
                     CGGFLGLPGGEVKADMQVVDVYYRKGDKLQENWVLIDIPYWLKQQGLDILERTKSIFN
                     A"
     gene            complement(8937..10259)
                     /locus_tag="KR294_002671"
     CDS             complement(8937..10259)
                     /locus_tag="KR294_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240736.1"
                     /translation="MKILYVGPGMVIDKILAVSKKNFPNIEADFLRYDRYIEVPDLLE
                     KYRGRVDAVLFTGKSPFKFFEKRQKDFVLSDYIPRHETTLYRVLLEITYLLKFDISRL
                     SIDTYDKAMMKRLYKEIGVEFKDEHMFFAEQKYLEEDYIKFVLEFHKYNYQNNDVCCC
                     ITGLEEAYHIMKKDNIPVVLALPSEDVMVQSIKNIQMRYIAKKNNENQIIVLAIKLNM
                     PSEYSLMKEDEYAYLSQRIKILDKLYHFNSRIDGVLVEQSRSEFMIFTTKKILELETK
                     KYRDIYLLDMIREVSVINTYIGIGYGKTANEAKFNAYESIKMAQSQKNDAAYVVFENG
                     EIMGPLKPNPTVKEKNSFDERFYQIAIETGLSANTVYKVFNKIINSGKTEFTSKELAT
                     ICGVSIRTMDRIILRLCDSGYCEVVSEQLMSKYGRPSRILRFKPFLLF"
     gene            complement(10617..12257)
                     /locus_tag="KR294_002672"
     CDS             complement(10617..12257)
                     /locus_tag="KR294_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacylase"
                     /protein_id="HBH0240737.1"
                     /translation="MFDVKIVNGIIVDGTGNSRYKSDVGIVGDKIMAIGDLSQKEAKE
                     TIDATGKFVSPGFIDFHTHSDLSLVYDKYTRSRIHTGVTTDVIANCGIGVAPIREEKK
                     QELIDYLGTRIIGTIPTKLELHWNTMQEYFDYLTENSPAVNVVAYVAQGPVRINEMGF
                     SKEPATLEQLKNMKLEVRKAMEAGCVALSSGLVYLPGAYTKKEEMAELCKELIPYNGY
                     YISHIRDEGDEEMEALDEAIYIAKTAGVPLHISHLKVMGHKNFGTIDEVFKKLDEAEA
                     DGLEVTFDCYPYTAGMTSLGALLPPWAFEGGVENMVKRLEVQENRDRIIKELEEGIPG
                     WQCFYQLAGGWNGVVLASVMTEANKYVEGKTLMEVAKINGENPFDTFFRLLIEEKSKI
                     QVVVHTQGQEDTDKVVCHPKSCIGSDSMDLSTEGLLSLGKPHPRAFGTFGRIFSYYVR
                     EKGMLTFEEAVKKITYLSAKRLGIYKERGLLKENYFADIVVFDPDTIEDKATYSNPKQ
                     YTVGVEYVLVNGKIALAGGKQTDVCAGRVIKNPLSIAK"
     gene            complement(12566..13222)
                     /locus_tag="KR294_002673"
     CDS             complement(12566..13222)
                     /locus_tag="KR294_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240738.1"
                     /translation="MYDKKMIKIGRISIGLAIIANFIPAIYVGIRFGQMPMLSVIFQI
                     WGLVAATYGVSWIVQPIAYYPTLGAPGSYIGWLAGSVGDIRMPAASMAQKIAGVEAGT
                     HEGEVVGTIGTCCSIFVSASMITIFTIVGYKVIPLLPEFVTNSFNYILPALFGAIYVD
                     IARKDIRAGGCTIAVALAIMYFGEKIGIPGGLLTLFIVLAGILITRVFFVIDNNKTKE
                     "
     gene            complement(13248..13949)
                     /locus_tag="KR294_002674"
     CDS             complement(13248..13949)
                     /locus_tag="KR294_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5058 family protein"
                     /protein_id="HBH0240739.1"
                     /translation="MKFQEMINSPGLWIVSSFLVIISVVQAIVFMKAALKEASNLGIE
                     RKGIKAAIRSASVTAIGPSLSPVITLLSLVAVIGAPTTWMRLCDVGAARTELGVISLT
                     SNLSGVEVGSAAFGAEAFSYALWGMALNNLGWLFVVFILGHRMRGIVEKMNMKYNPTW
                     VKKLLAGATVGLFAYLLSNQIKTFEIPKLTPAIISAIVMLVLTTLFKKNQRLQELSLG
                     IAMLIGMFGTQIILS"
     gene            14759..15238
                     /locus_tag="KR294_002675"
     CDS             14759..15238
                     /locus_tag="KR294_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBH0240740.1"
                     /translation="MDKTTFTNNILESEQTLYRVSKSILGNDHDCEDAVNNAILKAYE
                     KLDFLKEEQYFKTWLIRIVINECNSLRRKRLKSLSFEDVFKNKKIDEKDDYSDLYTAI
                     QSLPKKIKIPIVLYYIEGYSVDEVKEILDIPQGTVKSRLSRGRRLLKTKLENTEVII"
     gene            15235..16014
                     /locus_tag="KR294_002676"
     CDS             15235..16014
                     /locus_tag="KR294_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240741.1"
                     /translation="MNKNILNNSFPEIPESFHNSLSKTLNSLPEREENYKMINNKTHK
                     LPFGKGLVATLAITLILGTTALAVGQISSLVGKSSTKATYTSIPTTEQVKKDFNFTPN
                     IVSEFSNGYKFKGAYTVNEKALDKEDNVLGELKTLSFEYKNGNDEISLDTANDVLGKS
                     SDNLKVVDTYKDINISYEAFAQKFVPEGYKMTEQDKIDEKSGKYTFSVGPNNESDKVE
                     VNKFKFLTWKQDGVYYSFTVQDSNLSMNDLIKMAHEVIDAK"
     gene            complement(16306..16806)
                     /locus_tag="KR294_002677"
     CDS             complement(16306..16806)
                     /locus_tag="KR294_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH0240742.1"
                     /translation="MIEGIKFIKAEEKYIYSYWQTFDKIAKERKYLAMDEAFPFEETV
                     EFIKNIINKNLPQLFIIDLESDNCIGWCDVLPKTEKVGYLGMGILKEYREKGIGSNLL
                     KQIIDLSKEYGYEKIELDVFKSNSRAIHVYKSLGFVEVNTISSGFTWNDRPVKEEVIQ
                     MELTLI"
     gene            complement(17417..18124)
                     /locus_tag="KR294_002678"
     CDS             complement(17417..18124)
                     /locus_tag="KR294_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBH0240743.1"
                     /translation="MIFTKSNKYDKDFLMKNMMGPNCIKILEELTSKIKLEKGMRILD
                     LGCGKGISSIFLAKEFDATVFATDLWIEPTENYKRFKEFKLDDKIFPIQAEAHELPYA
                     EGFFDAVISIDSYHYFGNKEGFLDNHISPLVKEGGILAMAMPGLKEDFVDCIPDELIP
                     FWQDNMNFHSITWWNKLWSESESVIVEKCEALNCHDEAWKDWINCDNSYAINDKKMME
                     VENGKYFNTISLIARTK"
     gene            complement(18976..19845)
                     /locus_tag="KR294_002679"
     CDS             complement(18976..19845)
                     /locus_tag="KR294_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HBH0240744.1"
                     /translation="MVIIKAIELYKKLDLEFNIKNINDDWSFMNFENDFITPEFRKKY
                     IGLVLDNAQNINKVYTTTFPDKEIIKQVIDKDEKDILIFSHHAMGYIASDEGFPFHDI
                     PLSYMEEMKNRRISFYVLHSPLDNYSDYSTSVSFAKALGLEIVKPFCKYDDKIEVGVI
                     CKTSLKSIEEIKELIKKSVGHDVKLYDYGDSVLKDGLVAIAAGGGSYPFVAREVAELG
                     INLYITGFTKPLKHFEPVLEFHQIAKDNLINVIGATHYSTEKFACMGMVDYFKNLGLE
                     SEFLQGKYYLEDL"
BASE COUNT         6889 a         3514 c         2262 g         7184 t
ORIGIN      
        1 caatttctct atttatatga tttgtaaaat atagtacaag attttttatc attttcattt
       61 caactaaatt tgtaatattt tattcaatac ttaatcaata catgctttat aatactttac
      121 tcaatatata atcaatacat aatttataat ttgtaatact ttattcaata cataagtaga
      181 aatctctata tacataaatt cattttttca tacatcttac aaatttattt ttatttagat
      241 aacatgtata ttttttccat gaaaaataaa taataaaaaa tagtaaatat ggaaaatata
      301 aaattgatta acaataatta attacctgag gtgtgaatat gaaaatgcta aacaactttt
      361 ttaagaaaat caacaatcca gctcctgtct ttgcacagac aaaaatggaa agagataatc
      421 aaacagatga ttcactttct acaaaaccaa agactacatt tagagacgtt gctggattag
      481 acgaagtaaa agaagaacta tttgaaatag tcgattttat gaagtcacca caaaaatatc
      541 aaaaaatggg tgcaaaaata cctaaaggag tattatttta tggtcctcca ggaacaggta
      601 aaaccctact tgcatctgct gtagctggtg aaacaaactc atcatttttc aatgttaccg
      661 gttcagagtt cgttgaaaaa tatgtaggtg tgggagcaaa aagagttaga actctatttg
      721 aaaaagctag aaaagaagct ccaagtataa tatttataga cgaaatagat gctgtaggag
      781 caaagagaca tcttgaaagt aacaacgaaa aagaccaaac actaaaccaa cttttagttg
      841 aaatggatgg atttaataaa gattccaatg tattaataat aggtgctacc aatagacttg
      901 acttattaga tgaagcttta cttagaccag gaagatttga cagacacatt catataggtg
      961 caccaaacta tcacactaga tttgaaattc taaaggtaca tacagatgac aaacctatag
     1021 acaaatctgt aaatctagaa cttttagcta aaaaaactca tggtttcaat ggggctcatc
     1081 tttcaaatat agcaaatgaa gcagctatat ttgcagttag agatgacagt gagtgtatta
     1141 catcagaaca ttttgacaag gcacttgaaa gagttattgc agggttagaa tctaaaaact
     1201 ctgcactggt tgaaaaagag aaaaaaatag tagcatatca tgaagctgga catgctcttg
     1261 taagtgatat agtaggaatt tgtcctatac aaaaaatatc tatagttcct agaggacaag
     1321 cattaggtta tgttcttcaa ttacctgatg aagatagata tatttatact aaggatgagt
     1381 tgattggaaa aataaaaata ttacttgctg gaaaggcttc agaagaatta atatttaatc
     1441 ataaatctac tggtgcaaag gacgacttaa agaaagtcac tgaaatagct aaccaaatgg
     1501 tttgtgaata tggtatgagt aacttaggat ttatgactat tgatggaaat gataagactt
     1561 tcttatgtga taaggttcaa aaggaagcaa atcgtatagt tgaaatttgt tataaagaga
     1621 ctttggagat gttaaaggat aatcttgaag atttacattc tgtttctaaa ttcttatttg
     1681 aaaaagaaac tatgactcat gaagagttaa aagatttgat aggaaaagaa gctgtaaact
     1741 aatatagttt taaaaatttg aggctgtctc aaaatagaga taagcctctt tttattgtta
     1801 aagttataaa aatacatttg attttataca aaaaagtgcc tcataaacta aaaatttcat
     1861 tttgagacac ttacatattt taattacata ttttaatttt gtctatttac agaatattat
     1921 atctacataa aactaaactg atgtaaactt aactacctcc agtaatgttt gaagtggtat
     1981 aaaagctagt agcctagttt ctacacttat aatttatatt ttacataact aaatttagta
     2041 gatttttata ctcacaattt agaacgattg aaaacttaaa aatttcttat cagatatcta
     2101 caacttaatt aggtatctac cacttaatta aatatctacc acttaattaa atatctacca
     2161 cttaaagtgt agaacctctt tcaatcaatt caggttttaa catttcaaca actgactctg
     2221 gattttcttc atttaataag gacttaagta tgttaattgt tttttcaatc aacaaatcta
     2281 gtggctgtct aatcgtcgtt aaattataac tcttccatga agccatttga atatcatcat
     2341 atcctatcac tgataaatcc tctggcaccc tcaacttgta ctcaaacctt gcagcatcca
     2401 ttacaccaat agctatcaag tcacttgtgc aaaaaattgc tgttggagga tttgataatg
     2461 ctaacattct cttacctgct tcatatccag aatcataatc atagtttgca gattcttctt
     2521 taaggttatg aatcccactt tgtcttaact tagaataaaa tccaattttc ttttccattt
     2581 cttcacttgt ttctctcgta aattgaatat atcctatatt cttatgacct ttcttaagca
     2641 gatattcagc agccattccc ccaccttcaa ttgggtctac atagactgta cttattttta
     2701 taccaggtat aaaacgatta aaaagaatca caggaatatt gttttcttca caagtctcag
     2761 ccatcacctt attcatggcc gaagctgtaa taatcacagc ttctacttga aactgaatta
     2821 cttttgaaat tatactatct atactttgtt gtctaggaac tttaaaaacg agacactgtt
     2881 tacctatctc ttgaattttt tctacaaata aattgataat tctattgtaa aatggaccta
     2941 gactatcacc aactatcaat cctataacat tagtttttcc actaatcatt ccccgtgcta
     3001 ccaaattagg aacatatcct atttcgtttg ctacacgaaa aattctttct cttacttcag
     3061 gttttacgcc ctttccattt gcactaccaa atgctcttga aacagatgat tgagatactc
     3121 ctgccaatct tgcaacatct tttgaggtag ccgatttatt ataatgaact ttcttttgat
     3181 tcatttagta tttctcctta aatatctagt atttcttctt aaaattgtat caaaaataat
     3241 ataatatatt ggataataaa aaaagctaat acaattaatt cttgtttacc taaagaaaat
     3301 ggcactatag atactccatc tactttatcc attccttgag aaataaggtg atttctcata
     3361 ccaaatgcag tgtatttttt aatatcatct gcattatgat ttttctttaa aatgacacta
     3421 aaaatatatc caaatatcaa tgttattgta gcacctattg ctggattcca caaccaactc
     3481 acattatatt tattagaaat aaaaaatcct aaaactaacc ctacaataaa accaatagat
     3541 actcctttat cattagcttt atatgtaaac attgctagta caaatgcacc tgtagctggt
     3601 ccagcaaagt atgagatata gttaccaaca aggtcaagaa ttgatttgat gcttcctcca
     3661 aatcccataa taataaaacc tgtcataaca actcctataa ctacagttat aatcattgta
     3721 acttttaatg atgattcttt gttatctttt ttgaaataaa actcataaat atccttcgta
     3781 aaaacagttg tcatactgtt taatatagag tcgatactag acattgctgc tgcaaacaca
     3841 cctgcaataa taattccaat ggctcctact ggaagttcat ttaaaataaa agtaatcatt
     3901 atttcatttg aagtttcaaa tgtccttccc ccataaaaaa caaataaaat tactcctacc
     3961 aatagcataa agtagtaaac taaattcata acaaatgcac taactacaaa agaatttttt
     4021 gcacatttta aagatttaga tgttaaaact ctttgtactt gagattggtc aaaacaaaag
     4081 tatcttatcc acattacagt tccaccaatt aaagtagccc aaaaagtatt tgtcactgaa
     4141 atatccctac tgaaatcaaa tgtatttaat tttccactct gttgtgcaat ttgtaatgta
     4201 tcaaagaaac ttagattcat tccttttaag gctacaataa ttactataaa tacagcactt
     4261 attactacta tcatttgaat actatcagtc catataactg ccttaatccc acctaataga
     4321 gtgtatataa ttgatacaag tacaactatt gggactaaag cataaagtga ccagccagta
     4381 atcatttgaa taataagcac tggaatatat accatagaac tagcttgaat caatgaatta
     4441 ataaaaaatt gaataatagt taatcctctt gaataatttc ctaaacgaag tcccatatat
     4501 tcatatatag aggttatttt taatttatag ataactgggg tggtaatgct cagtgcaaaa
     4561 aatattgcta aaggtactgt aatattaacc attactggat acattccatc tacatatgcc
     4621 catccaggac cacctataaa gccatttgca ctaatcatag tagctgcaac tgataaagca
     4681 attggaatcc atggcattga cctacctgcc aagaaataat cttcttgatt tttattatct
     4741 tttcctgaat aataaccaat aactaacatt aatagcaaat atcctattat aatacataca
     4801 tcaattgatg aaatcataag ccaccccttt ctaagtaaca aaataaattc ctagtatttt
     4861 attttttatt atttaacgtc tctggtaaga ataaccatac aatagcacct gctacaaaga
     4921 ctgcgattga tatgtaaaag atagtcatca tacctaaagt accagaagct gtaccagcta
     4981 tagcaggtat tgcaaacgta gatataatcc ttcctccatt aaatgacata ccagatgaca
     5041 acgaacgata tttacttggg aacaactctg tgtagtatgc tccccatgct ccagaatatc
     5101 caacagcaac acctagtaat actgatatca tatagaatgt tgttgtatta tctccaccta
     5161 attttgtata tataaaaaca aatactgctg ctaatgccat acctataaaa ggtatttttc
     5221 ttccaaattt atctgcaatt gaaccccaga ataaatatcc tactaattga ccaattcctt
     5281 gtaaactata tatagaccca gccactgctg ctgacattcc tattcctgtc actaggtatg
     5341 tagttgcatt atttgaaaat gctgaatatg ctgtaaaatt tgcacctgat aaaagaatcg
     5401 ttcccaatcc aatccataag tattttccct tatacatact tatatagcta atcttttcac
     5461 cagtttcttt tcccttttta actaattcct ttgtatactc caaatcatct ggcacaaaga
     5521 agattgctaa gatagctcca actataggtg gtataatcgc agtatacatc aatatttgcc
     5581 aatttgcatc acctaaaacg ccatatactt tcccaccaaa aatcattgct aatgaaaata
     5641 aagcagttaa tatagcagct aacttaccac gatatttact tggaaacata tctgcaacta
     5701 aaggcatagc tgttccaaat acgcctccca acactactcc tgtacacaaa cgtgctattt
     5761 tccataacat aatattggta ggagataaca ttggtataaa tgttgtcaat ccaatcagta
     5821 aagcaacgct aattaaagtc ctcttcttcc caatttttgt agaaatcacc ccaaaaataa
     5881 atgtacctgg aattgtacca aaagacataa ctgcaaatat ttcttctgtt tgttttaatg
     5941 aaaaaccaaa tcccccatct gctaaagcat aaatcattgt tggtttaata aaagtaccca
     6001 ccataaaatt gtagcaataa aaaaagtata ttaaagcaat tgaaaaaaat gcaattcctc
     6061 tttttaggtt tgaatagtct tttcctaata tgatatcatt ttctatttca accgttgttt
     6121 tcatattttt ataattcccc cttttaaatt tagtcataat tttgctaaaa gtttaaacat
     6181 ctatttttca tatacattcc ccacttaaat tttataaagc aatacttccc tatatatatt
     6241 tcaaaactat ttatactcta aacagcttta ttcttctact cccatataca tttgttttaa
     6301 tacatccata ccatcaaaag ttatccactc ctcctttact ttaccttgta gtatatgata
     6361 atgattgatt cccattactt ctatatgctt tccagaaggc tgtccaaaaa atcctatacc
     6421 ttcatttatt ccacgtaatc tccatcttac agatacatca taaccttcat ttttttctct
     6481 ttgattacaa gttactcttt ccacttcata acttccattt ggaattgatg caagtaaact
     6541 tacaatcatt ccttgaatct catcataacc atttaaatct ttatcacata taaaatgtac
     6601 tactgcatta tcatgatagt attttttaac ttcatttata tatttataat tataaatacg
     6661 gcttgtcatt tcaagcatca tttcgccaac agaatcatct tttgcttgat acttagttgg
     6721 cataaattga ccatccatag attcacagat accataagtt gattgtaaac taagcacttt
     6781 agattcactt gcctttgcca tactctttgc tacttcctga gggtttaatc ctaattgagt
     6841 aacaatccat aaattatctc taaccaacca ttcttcgtgg attctattgt tagttgtggc
     6901 acaatcaatt acagttctaa agtttatttt tctacctgtt gctggtccaa aattactatc
     6961 acctaagtta gttgctgtag acaaaacacg gtgagaagat aaaaaaccat cagcaccaaa
     7021 gttagaccat attacatttt gaccaattaa tcttctatca ggaaacgcat gtaatgtttg
     7081 aagagtattg gaaataacat ctttaatacc aactaaattt gaagagccac aatgcattgt
     7141 aacattattg tgatatgtat cataaataac gcctatacct ttttcttccc agatattatg
     7201 tgtaatcttc ataatataat ctacaaaatc tctatactta gaatcaaatc caggtatttc
     7261 ctgttccctt tttgtctgtt ttgaaaaatc attgtaatcc attactccaa caggcgttac
     7321 ttctaatgaa tctccatagt aaatttttgt agatgacata ttatcttccc ccttaaatat
     7381 aattttttta tttttttcag taagagtatt tgtatttaat ttatctgtat ccactgtatc
     7441 tatgttaact ttatttatgt cggatttatt tgtgtttgtt ttatctatat tccctttatc
     7501 tatatttcct ttatctatat ttcttttata tgtgttcgtt ttattctcat ttgtttgatt
     7561 ttcatttata ttactaaaat tagtttgatt cattttagct ttgttttctt taaccgtaca
     7621 tgattcaagc ccacttgtag aaacttcttt ttcttcttct ttacttgttg cattattttt
     7681 gttggtagat gccactttat atcccccttt gttttagaat acgtatgcat aactaagcat
     7741 taaaaatact tttagttctc tcaagaatat caagcccttg ttgtttcaac caataaggaa
     7801 tatcaattaa cacccagttt tcttgaagtt tatcgccctt acgataataa acatcaacaa
     7861 cttgcatatc tgctttaacc tctccacctg gtaatcctaa aaaacctcca catggtacat
     7921 tagtcagatt aggccatcca aagaaacaag caaaattacc ttctgcaaat ctacatacat
     7981 gcccattgaa agtctttcct tttaaattat ttctaaatgg tagctggtgt tgctcttgat
     8041 atctaggtat agtataagaa gcaccaattc cacctggacc ataccaaatc atatctttag
     8101 cccaagattt ttcaagtatt tctggtgggc atcccatagc accactttca tttaattcag
     8161 ataaatcatc taccatttta tttactaatg ctaaagtttt tactccttca acttcatctg
     8221 catcttcaaa aagtaatcca ttatggtcaa ttggccctgg atatacaaaa tatgaacctg
     8281 tttgtggtgg caatggatta actcctgctt gaatcataaa cccaattata tctacaaata
     8341 atccagtttt agcaatttta ccatcttgaa cacagttaaa ttctgcatat cttaaactaa
     8401 tcattttgcg agtatgttta atgccaagcc aatccttatc aaaaagtccc ataaaatgcc
     8461 ccatactcat tacccattca ctattgtcaa tctcatttgt tcctgcaatg aaaatatctt
     8521 gtcgtctttg catattactc aatgattttt ttaaaggctt ccaaaataca tctgctacat
     8581 tttcagtgcc ttcttgttca cgaaatggat acacaccttt ccagttataa tctgatttca
     8641 tatgttgctt taagacattt tcaacctcat ccccagtagc attttctaat gcttcaaaat
     8701 aatttcttac aacttttttt gaatcctgat attttcccat aattatctcc tcccagattt
     8761 atttaagtta taaattaact ttctcatttt atgcatacga tttccttttt aatgattttt
     8821 tagctgtttt aactttattt tatgaataca tatgcatttt tctaaatatt aacatatatc
     8881 taaaaaattg taaagaaaat gttatcataa aaatttaatt tttgacttat atctatttaa
     8941 aacaacagaa aaggtttaaa acgtaatatt ctactgggtc taccatactt gctcataagc
     9001 tgttcactca ctacctcaca ataaccagaa tcacacaatc taagtataat cctgtccata
     9061 gttctaatac ttacaccaca tatagtagct aattcctttg atgtaaattc agtttttcca
     9121 ctatttatta ttttattgaa tactttatat acagtattag cacttagccc tgtctctata
     9181 gcaatttgat aaaaacgttc atcaaaacta tttttctctt tgacagtagg atttggcttt
     9241 agtggtccca taatttctcc attttcaaaa actacatatg ctgcatcatt tttttgactt
     9301 tgagccatct taatactctc ataagcgtta aatttagctt catttgctgt ttttccataa
     9361 ccaattccta tataagtgtt tataactgaa acttcacgaa tcatatccaa caaataaata
     9421 tctctgtatt tctttgtttc taactcaagt atttttttag ttgtaaaaat cataaattca
     9481 cttctactct gctctaccaa aacaccatct atacggctat tgaaatggta tagtttatca
     9541 agaatcttaa tcctttgtga aagataagcg tactcatctt ccttcattag tgaatattct
     9601 gaaggcatgt tcagtttaat agcaagaaca ataatctgat tctcattgtt tttctttgca
     9661 atataacgca tctgaatgtt ttttatactt tgcaccatta cgtcctcaga aggcaaggct
     9721 aaaactactg gaatattatc ttttttcatt atatgatagg cctcttcaag acctgtaata
     9781 caacaacata catcattatt ttgataatta tatttatgaa attcaagcac aaactttata
     9841 tagtcctctt ctaaatactt ttgctctgca aaaaacatat gttcatcctt aaattcaact
     9901 ccaatttctt tatacaatct cttcatcata gccttatcat aagtatctat actaagtcta
     9961 ctaatatcga atttaagcaa atatgtaatt tcaagcaaca ctctgtacaa tgttgtttca
    10021 tgtctaggaa tataatcaga caatacaaaa tctttttgtc ttttttcaaa aaatttaaat
    10081 ggcgacttac ctgtaaaaag aactgcatcc actctacctc tatatttttc caataaatca
    10141 ggtacttcaa tatatctatc atatctaaga aaatctgctt caatattagg aaaattcttt
    10201 ttacttactg ctagtatttt atcgattacc atacctggtc ctacataaag tattttcatt
    10261 tcgtctctcc tttcctaatg atactattat ctcttaaaac attttctaaa cctaccatga
    10321 ctaaaggcac aggactcctg attcatagaa ttttgaataa tcaattatac ctaatataaa
    10381 aagttacttt aagtttttta attacgacta tctgttgaaa catttttgta tttaaatttt
    10441 tgtatttaaa tcttattcat taatattaat tacattttac aattaatata ttgttttttc
    10501 tacttaaagt taaattcttt agaaaacaca agtagagtaa tctttattaa tttaacaaaa
    10561 atagccttcc ttaatattca aagaaagact atttttataa aagttcttaa tgtattctat
    10621 tttgctatgc taagaggatt tttaattaca cgtccagcac atacatcagt ttgctttcct
    10681 cctgccaatg caattttacc attcaccaac acatattcca ctcccactgt atactgttta
    10741 ggattactat aagtcgcttt atcttctatt gtatctgggt caaataccac aatgtcagca
    10801 aaataatttt ctttaagtag acccctttct ttataaatgc ctaagcgttt tgctgaaaga
    10861 taagttatct ttttaactgc ttcctcaaaa gtcaacatac ctttttctct aacatagtaa
    10921 gagaaaattc gtccaaaagt accaaatgca cgaggatgag gctttccaag agaaagtaaa
    10981 ccttctgtag aaaggtccat actatcagaa cctatacatg actttggatg gcaaacaacc
    11041 ttatctgtat cctcttgacc ttgtgtatga acaactactt gaattttact tttttcttca
    11101 atcaaaagcc taaagaacgt atcaaatgga ttttcaccat tgattttggc tacctccatt
    11161 aaagttttac cctctacata tttatttgct tcagtcatta cagaggctag tacaacaccg
    11221 ttccacccac ctgctaattg gtagaaacat tgccatccag gaatcccttc ctccaactct
    11281 tttataattc tgtctctatt ttcttgtact tctaatcgtt ttaccatatt ttctacaccg
    11341 ccttcaaaag cccaaggagg taaaagtgca cccaaagatg tcattccagc tgtatatggg
    11401 taacaatcaa aagttacttc caaaccatct gcctcagctt catctagctt tttaaatacc
    11461 tcatcaatag ttccaaaatt cttatgaccc ataactttta aatgagaaat atgtagagga
    11521 actcctgcag tcttagctat ataaattgct tcatcaagag cttccatttc ttcatcacct
    11581 tcatctctaa tatgagatat atagtatcca ttgtatggta tcaattcctt acataattca
    11641 gccatttctt ctttctttgt gtatgctcct ggtaaataaa ctaatcctga tgaaagagct
    11701 acacatccag cttccatagc ttttctaact tccaacttca tatttttaag ttgctctaaa
    11761 gtagctggtt cctttgaaaa tcccatttca ttgatacgta caggtccttg tgctacataa
    11821 gctacaacat tgactgctgg agaattttca gttaagtaat caaaatattc ttgcattgta
    11881 ttccaatgaa gctctaattt tgttggaatt gtaccaatta tcctagttcc aagatagtca
    11941 attaactctt gcttcttctc ttctcttatc ggagcaactc ctataccaca gtttgcaata
    12001 acatctgttg ttacacctgt atggatacgg cttcttgtgt atttatcata cacaagagat
    12061 aaatcagaat gagtatggaa atctataaaa ccaggtgata caaattttcc agttgcgtct
    12121 atagtctctt tagcctcttt ttgacttaaa tctccaatag ccatgatttt gtctcctaca
    12181 atccctacat cacttttata tcttgaattt cctgtaccat caacgattat tccattgaca
    12241 attttaacat caaacatgct ttttctcctt tcaagactta tttatattca tatttcttaa
    12301 taaacaatcc tattcttttt ctcaacaaat aattctagtc tttctcctta ataaacaatc
    12361 ctattcctta ttctcaacaa ataattctag tctttctcct taataaacaa tcctattctt
    12421 tttctcaaca aataattcta gtctttctcc ttaataaaca atcctattct ttttctcaac
    12481 aaataattct agtctttctt cttaataagc aatcctattc tttttctcaa caaataattc
    12541 tagtctttct tcttaataag caatcctatt cttttgtttt attgttatca attacaaaga
    12601 agacccttgt gataagtatc ccagctaaca caataaacaa tgttaataat ccacctggta
    12661 taccaatttt ttcaccaaag tacataattg ctaacgctac agcaatcgta catccaccag
    12721 ctcgaatatc cttacgtgca atatcaacat aaattgctcc aaataatgct ggaagtatat
    12781 aattaaatga attagtaaca aattcaggta acaaaggaat tactttatag cctacaatgg
    12841 taaaaatggt aatcatagaa gctgatacaa agattgagca acatgtacca attgttccaa
    12901 caacttcacc ctcatgagtt cctgcttcta cacctgcaat tttctgtgcc attgatgctg
    12961 caggcatacg tatatctcca acagaacctg caagccaacc tatataagaa cctggagctc
    13021 ctagtgtcgg ataataagct ataggttgaa caatccaact aaccccataa gttgcagcga
    13081 ctaaccccca aatttgaaat ataacagaaa gcattggcat ctgaccaaag cgaataccta
    13141 catagatagc tggaataaag tttgcaataa ttgcaagacc tatggaaatt ctccctattt
    13201 ttatcatctt tttatcatac ataattatca cctcttatcc tttttaatca cgataatata
    13261 atctgtgtac caaacatacc aattaacatg gcaataccta aggataattc ttgtaatcgt
    13321 tgattctttt taaataaagt tgtcaatact agcataacta tagctgaaat aattgctggt
    13381 gtaagttttg gtatttcaaa tgtttttatt tgatttgaaa gaaggtaagc aaataatcca
    13441 actgtagctc ctgcaagtag ttttttaacc caagtaggat tatacttcat gttcatcttt
    13501 tcaacaattc cacgcattct atgacccaaa ataaatacaa caaacagcca acctaagttg
    13561 tttaaagcca ttccccatag tgcatatgaa aaagcttctg ctccaaatgc agcactacct
    13621 acttctaccc cagataaatt ggatgtaaga gatattactc caagctctgt tctagctgct
    13681 cccacatcac agagcctcat ccaagtcgta ggagcaccaa tcacagctac cagtgataat
    13741 aatgtaataa caggagatag agaaggtcca atggctgtaa cactagctga gcgaattgct
    13801 gctttaattc ctttcctttc aataccaaga tttgaagcct cttttagcgc cgctttcata
    13861 aatacgattg cttgaacaac tgaaataatt actaaaaaac tagaaacaat ccaaagacct
    13921 gggctattaa tcatttcttg aaacttcata ctttattcct cctttaaaat aaatttttca
    13981 gcattttatt gtgagctttc tttctgtaat cttgttatgt ttttatattg ttttaattta
    14041 ttttatctaa gatatcgtat ctttaatagg agattatctg tcttaaagtc tcactaaaaa
    14101 cattaatact taaatatttt attgataatt agtaaatatc agaaaattca catattattt
    14161 ttttaacctg caattaactt ataaggtctt ttattatttt gacatttcaa tataaaactt
    14221 ttaatcaaaa aactttatta ttttaaaaaa aattattatt tttataattt atatttttta
    14281 agtttattta tgttcatctc tatctaaaat aatgacattt ctaactctta attctcattt
    14341 aagtttcatt gttttttctt aaaagcctac ttttagtcaa gatactgtta tctttactca
    14401 ttaattaaag aacttatttt aaatctatac atgaagtaaa taatccaaaa gcattatttt
    14461 ctaactactc aacattaaat acttactatt ttctaattac tcaatataaa cacttactat
    14521 aaaactaaat atataaatgg cttctaaaat ttaatatatc tacatggctt tatatatgac
    14581 gagaaaaaat actagaaaaa aatatattat agaatatttg tatagaatag acaaaacttt
    14641 caaacttaaa tttattaaat aatcataaaa aaagtgaacc atctatagta aaattttatc
    14701 taataagtga aaggcaaaaa agtagcgcta cgatttgcat agaaaggaag gaactcagtt
    14761 ggataaaact acatttacaa acaatatact tgaatcagaa cagactttgt atcgagtatc
    14821 taagtctatt ctaggaaacg accacgactg tgaagatgcc gtcaacaatg ccatcttaaa
    14881 agcatatgaa aagttggatt ttcttaagga agaacaatac tttaaaactt ggttgattag
    14941 aatagtcata aatgaatgta attcattaag acgaaaacga ttaaaatcac tatcatttga
    15001 agacgtcttc aaaaacaaaa aaattgatga aaaagatgac tacagcgatt tgtatactgc
    15061 tattcaaagt ctacctaaaa aaattaaaat tccaatagtc ctttactata ttgaaggtta
    15121 ttcagtagat gaagttaagg aaatattaga tatacctcaa ggaactgtaa aaagtagatt
    15181 atcaagagga agaagattat taaaaactaa attagaaaac acggaggtaa tcatatgaat
    15241 aaaaatatat taaataattc gtttccagaa attccagaaa gttttcataa tagtttaagt
    15301 aaaacactaa atagtttacc agagagggag gaaaattata aaatgattaa taataaaaca
    15361 cataaattac catttggaaa aggcttagtt gcaactttgg ccattacttt aatattgggc
    15421 acaacagccc ttgcagtagg acagatatcc agtctagttg gaaaatcaag tacgaaagct
    15481 acctatacat ctatcccaac tacagagcaa gtaaaaaaag actttaactt tacccctaat
    15541 atagtttctg aatttagtaa tggatataaa tttaaaggtg catatactgt aaatgaaaaa
    15601 gcacttgaca aagaagataa tgttttagga gaattaaaaa cacttagttt tgagtataaa
    15661 aatggtaatg atgaaatatc tcttgacaca gcaaatgatg tacttgggaa gagttctgac
    15721 aatctaaaag ttgtagatac ttacaaagat attaatattt cttatgaagc attcgcacaa
    15781 aagtttgtac cagaaggtta taaaatgaca gaacaggata aaattgatga aaaatcaggc
    15841 aaatacacat ttagtgtagg gccaaataat gaatcagaca aagttgaagt taataaattt
    15901 aagtttttga catggaaaca agatggagtt tactattctt ttacagttca agactcaaat
    15961 ttatctatga atgacttaat taaaatggct catgaagtaa tagatgcaaa ataaacataa
    16021 gtaataataa gttgtttatg agtttattat ttatgacttt aattttttta ttagtaaaca
    16081 tggttgtatc ttccatcttt atattttctt taaatttaat atataaaatt ttagatattt
    16141 agctaccttc aaaagaacca ttattaaaaa gcccttaaaa atatttcttt tatatggaat
    16201 tttaagggct ttaactttat tttatacaag tgtatatgga atttcaaggg ctttaacttt
    16261 attttataca agtgtatatg gaattttaaa gactttaact ttattttata taagtgtaag
    16321 ctccatttga attacttctt cttttacagg tctatcattc catgtaaaac cactagatat
    16381 tgtatttacc tctacaaacc ctaaagattt ataaacatga atagctctac tattactttt
    16441 aaatacatca agctcaattt tttcataccc atattctttt gataaatcaa taatttgttt
    16501 taaaagatta cttccgatac ctttttccct atactcttta agaataccca tgcctaaata
    16561 accaactttt tcagttttag gtaaaacgtc acaccaacca atacagttat ctgattctaa
    16621 atcaattata aacagttgtg gtaagttttt atttataata ttttttataa attcaactgt
    16681 ttcttcaaaa ggaaaggctt catccatagc tagatatttc ctctcttttg ctattttatc
    16741 aaaagtttgc caatacgaat aaatatactt ttcttctgcc tttataaatt ttatgccttc
    16801 tatcaactta acatttcccc tttttaattt gtgattgtag ttaacttatt ttatatgatt
    16861 ctagtttata atgctatata aattactata tattagctta aaatatcttt gtatatttct
    16921 ataaaattaa aaccaatata tctatctctt gtatctctat taaaataatt tttaatagta
    16981 taataaatat agctctttaa tcttttgagt atatatactt aatcattttg aaatttgatt
    17041 taaagtataa taaaatatat aaaaaaatat ataaaatggt actataaaat ttttaatctt
    17101 catcaatacc ttttttgctt tcattgttaa aactattttt tctattagtt tatttcttat
    17161 aaaacaaaca tttagtatta aaatatatat cacacaatag tatttgcaat ttaactttaa
    17221 aaaataaaaa tacccaactg acctaagcaa ctcgattggg tataaataat ctaaaaaatc
    17281 atttttgtat aaactcttta tttaacttac atttttattt accttctact ttaattcaac
    17341 ttatatttct atgcttctta tactctcatt caacttatat ttctatgctt cttatacttt
    17401 tataaattca tcacaattat ttagttctcg ctatcaaaga aattgtatta aaatactttc
    17461 cattctctac ttccatcatt tttttgtcat ttatagcata tgaattatca caatttatcc
    17521 aatccttcca agcttcatca tgacaattta aagcttcaca tttctctaca atcacagatt
    17581 ccgattcaga ccaaagttta ttccaccatg taattgaatg gaagttcata ttatcttgcc
    17641 aaaatggaat gagttcatct ggtatacaat ccacgaaatc ttcttttaat ccaggcattg
    17701 ccatagcaag tattcccccc tcttttacaa gaggtgatat atgattgtct aaaaatcctt
    17761 ctttgtttcc aaaatagtga taagaatcga tacttatcac cgcatcaaag aaaccttctg
    17821 cataaggtag ttcatgtgcc tctgcctgta ttggaaatat tttatcatcc aatttaaact
    17881 ctttaaatct tttatagttt tcagttggtt ctatccataa atctgttgca aatacagtag
    17941 catcaaattc ctttgctaaa aatatcgaag atataccttt accacaacct aagtctaaaa
    18001 tacgcattcc cttttctagt tttatcttac ttgttaattc ttccaatatt tttatacaat
    18061 taggtcccat catatttttc atgagaaagt ccttatcgta tttattactt tttgtaaata
    18121 tcattctatc tttcctttcc ctatcagtta ttatttatta aattttatac gtttgatttt
    18181 ttatttttta tatgcttctt atattgagca atctcttttt tattcattct ttaacagaca
    18241 attttaatgt gtaattttat ccactctgtg atagtaactt taatgaataa tcttatctac
    18301 tgtgatagtt aactttgatg ggtaatttta tctactctac aataatcacc ttaatgagta
    18361 tcttatctac tctatgataa ttattttagt gagtaatttt atctactcca cagcaatcgc
    18421 tttaatgagt aatcttatcc actctatgat agttatttta gtgagtaatt ttatctactc
    18481 cacagtaatc gctttaatga gtaatcttat ccactctata atagtcactt taatgagtaa
    18541 tcataatttt tatatcattt tagatactta ctctaataag aagtcatttt ctaatactta
    18601 ataagtttta attacttcca ctttaaccta tatactaatt aacttattta atttagtgca
    18661 tatttgacac tttacctttt attataccat ttattatcat aaatataata attctatttt
    18721 tttaaaataa atatttataa attctaatca atcgtaaata ataatctaaa atacatcaaa
    18781 aaataaacta aaaaatatcg aaaaataatt taaaagacat caaaactaaa tcttctaatc
    18841 agcaattaaa agtctatttt cttagtttaa aaaataaaga tagatttttt caaaacacta
    18901 gataaatagg taaaaaaata aacagttagt aaaataaatt tttactaact gtttattttt
    18961 attgtttaat atgtcctata aatcctctaa gtaatatttt ccttgcaaaa attctgattc
    19021 taaacctaga tttttaaaat aatcgaccat gcccatacac gcaaattttt ctgtagaata
    19081 atgagtagca cctataacat taattaaatt atcttttgct atttgatgga actctaatac
    19141 tggttcaaaa tgttttaaag gcttagtaaa cccagtaata tatagattta taccaagttc
    19201 agcaacttct cttgctacaa atggataact tcctccccct gctgcaatag caactaaacc
    19261 atcttttaat acagaatctc cataatcata caatttcaca tcatgaccaa cagatttttt
    19321 aattaattcc ttaatctctt ctattgattt tagtgatgtt ttacatataa ctcctacctc
    19381 aattttatcg tcatatttac aaaatggttt gactatttct aaacccagag cttttgcaaa
    19441 actaacagaa gttgaatagt cactatagtt gtctagtgga gaatgtaata cataaaaaga
    19501 aattctacga tttttcatct cttccatata agatagtggt atgtcgtgaa atggaaaacc
    19561 ttcatctgat gctatgtatc ccattgcatg atgtgaaaaa attaaaatat ctttttcatc
    19621 tttatctata acttgcttaa ttatttcttt atcaggaaaa gtagttgtgt atactttatt
    19681 aatattttga gcattatcta atactaatcc tatgtatttt tttctaaatt ctggagtaat
    19741 aaaatcattt tcaaaattca taaaactcca atcatcatta atatttttaa tattaaattc
    19801 taaatctaat tttttataaa gttcaattgc cttaataata accactcct
//
LOCUS       DAEPKC010000075        19404 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.075, whole genome shotgun sequence.
ACCESSION   DAEPKC010000075 DAEPKC010000000
VERSION     DAEPKC010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 19404)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19404)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19404
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.075"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            325..903
                     /locus_tag="KR294_002680"
     CDS             325..903
                     /locus_tag="KR294_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_126936537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HBH0240745.1"
                     /translation="MGITLSKGQKVDLTKGNPGLKNILVGLGWDTNKYDGGFDFDLDT
                     AAFLTGASGSVTNDGDFVFYNNLKHTSGAVEHLGDNRTGEGDGDDEQIVVDLSKIPGE
                     ISKISFTVTIHDATERRQNFGQVSNSYIRIVDKDTNEELIKYELGEDFSIETAIVVAE
                     IYKHNGEWKFNALGSGFEGGLAALCGNFGINL"
     gene            942..1520
                     /locus_tag="KR294_002681"
     CDS             942..1520
                     /locus_tag="KR294_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_126936537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HBH0240746.1"
                     /translation="MAIVLKKGQKIDLTKGNPGLKNIKLGLGWDTNSFDSGYDYDLDV
                     SVFMVGESQRVEKDEDFIFYNNLKHPSGAVEHLGDNRTGEGDGDDEEILVNLETMPKH
                     IQKIAVTVTIYEAAERRQNFGQVSNSYIRVLNSENDEEILRYDLGEEFSIETAITVCE
                     IYKYNGEWKFSAVGAGFEGGLEALCRNYGLNV"
     gene            1606..2235
                     /locus_tag="KR294_002682"
     CDS             1606..2235
                     /locus_tag="KR294_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HBH0240747.1"
                     /translation="MSINLSKGDKIDLKKSNPGLSNILVGLGWDPVQQSGGGFFKSLF
                     GGGQADIDCDASVFMLNQEGKLSGIKDLIYFGNLKSACKSVLHTGDNLTGEGTGDDEQ
                     ILVNLDKVPSNIHKLLFVVNIYNCVDRKQHFGMIENAYIRVEDQGNKKEIAKYNLSDN
                     YSEKTTLIVGAIYRKDGSWQFKAIGEGTKDAGLKEVMQNLDRIECAYGI"
     gene            2225..4984
                     /locus_tag="KR294_002683"
     CDS             2225..4984
                     /locus_tag="KR294_002683"
                     /EC_number="7.2.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-translocating P-type ATPase, PMCA-type"
                     /protein_id="HBH0240748.1"
                     /translation="MEFNNDIKYYNVDKEEVTKDLSVNPEKGLSESEVKTRREKYGLN
                     EFTPKEEGSFWDDLKESLSEPMIVILIIAAVVSAVIGETHDAIGIVGAIAIGIAIGMI
                     TEGRSKKAAEALSKLTENIEVKVLRDGEVHQISKSELVPGDIVYIETGDMVPADGRLI
                     ESINLKIREDMLTGESDDVSKKCDVVVSMEEIESKGAVVVQEPIPAKQINMVFGGTLV
                     AYGRGALVVTSIGDNSEMGKIAQNLSETDEQTPLQIKLGNLGGLIAKVSSAVAGLLFI
                     FMVFQMISKNVLNVDMSGILPFLESIDPVKTAFTVCVALIVAAVPEGLPTMINMTLAI
                     TMQKMAKINALVTKKEACETIGSVSVICSDKTGTLTENRMTVEVAYVDGRYIESSEEE
                     INSYFEENCMINSTADVEHNDGDIKYLGSATECALLLYYKNVDYRQVRKNSNIVAQNP
                     FTSDSKRMTSVIGQDNHHVLLSKGAPEVLLELCSHIQRGKDIVPLTENIKHEILEEIK
                     KLQIKSMRTLGFAYKEISQAEEEAAVTAESDAMNVSAMENNLVFSGFVGIRDPLRKDV
                     IESVNTANKAGVSVKMLTGDNINTARAIGEELGLLKNNMRVVEASYIDTLDDEELKQE
                     IQSISIVARSKPDSKMRIVSALQKSGDVVAVTGDGINDAPALSKADVGIAMGISGTEV
                     SKNAADIILTDDSFSTIVKGIKWGRGIYDNFQRFVQFQLTVNVIAFLVAIISQVMGQE
                     MPFTTIQLLWVNIIMDGPPALALGLEPVRDHVLNRKPVDRKANIISKSMVYTIVLNAF
                     YITAILMLQSTFNFLGVDEAHKGTVMFALFAFSALFNAFNCREFNADSIFPNFTHNKL
                     ALQIIVLTGIAQVIFTQLFQDFFNSVAMDFMTWVKVLCVAASVIVVNEVVKCIIRLVK
                     PKKTA"
     gene            5071..6633
                     /locus_tag="KR294_002684"
     CDS             5071..6633
                     /locus_tag="KR294_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceG family protein"
                     /protein_id="HBH0240749.1"
                     /translation="MGDSKVFEKIFSSQSDRGNYTPSKGYLSYFISYIGLEDEVLYNL
                     EIFKTKQNIDSKKDIALFTDVIANPSDFDIINYFKSGLQKYRTSMEDVDINILGFEEI
                     DYKIKQAMDRVLKEEEKEFTNDRVKQNFIVKIMAWIKIYIGALDINKNEAPKVIFYGD
                     IKKHEVYLLLILYLAGFDVLYLNPNSKSNIDILKSERYNIEFEEANIIEEKISFEERV
                     ILGEKIDKSSVKKAFTVGAEASKRISEELLNDAGFIKPWQLQDRKIKNLLLSSTVDEI
                     SIYWNQPLKLRPGFKFNDAIVEAPNFLSKINGIYNDKNEYIKFLDLLRDSESSTFIEF
                     NGDVDRFSKAFTREAFSLSFLLDSKGAIDKNSVLNNKDYSISTLALNQQIMILEKVEE
                     LLEGSMFLNGLSGEDKIKGLFTVLHMDKKFVHMMNNFDYSLINPKLIIYMYKSIVFDK
                     EIVFLMLLLSKIGFDIIILCPGGENNIENVINNQLIDVHRLDKMVYDLKLNSLENDIP
                     LLKKIFGKRRRF"
     gene            6634..7770
                     /locus_tag="KR294_002685"
     CDS             6634..7770
                     /locus_tag="KR294_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HBH0240750.1"
                     /translation="MGININSFSKDKNSVEVTENLPTAVQEENFDIMEYTNNKKNELR
                     KSKEVEALTSLIEVENPDTILQFGRKASEGVARVSDSLLNTIKLNRNEENSKMLVHLT
                     KIMDKFDLDDFQETKEPNFVQKLFKKANNAIEMMFQKYETLGGEVEKIQIELEQYERD
                     IALSNKQIGAMLNENFEFYNELQKYIVAGEMAIEEMDNEILPFFKQKSETSGDQMDVV
                     NYQELLKVYDMLNQRVYDLRIAENIAIQTIPMLRGMQHNNYGLIRKINSAFVVTLPVF
                     KQCLSQAILLKKQELQAKSLKALDDKTNELLLRNAQNVSTQSAQIARMAGTSSVQIET
                     LEKMYNTIKSGIDETMRIEENNRALIKDNTKRLEELNTTIIYNK"
     gene            7834..8910
                     /locus_tag="KR294_002686"
     CDS             7834..8910
                     /locus_tag="KR294_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HpcH/HpaI aldolase/citrate lyase family protein"
                     /protein_id="HBH0240751.1"
                     /translation="MKYFDYICKDDLERIFLKEPEDFSAKTEKDVLKYALGAFLYVPA
                     TQYNMIYKSIIGDVKGVRPLAICLEDAVGVNGELEAIENLRLILKNISNESITNKDGI
                     PLIFVRIKDVEQLLRIKEIIIKNRHSITGILIPKANSELIENCIEALDSMNLQDMYVI
                     PIIETKEFIYNEKKELSFTNLYNAILRHKSRILSIRVGITDILGMYGIRRDKNFSIYN
                     NLICSSFILDIITYLQRPELDIPISGGVSEFFDMTNKDIRNKYIEEILLDKYHGLIGK
                     TVIHPMQIQIVQALSTVSYEDFTDALDILDSTDSKYGVSKGVLGERMNETNPHFLWAK
                     KTLILSKIYGVLNKGVDYEELLKF"
     gene            8888..10126
                     /locus_tag="KR294_002687"
     CDS             8888..10126
                     /locus_tag="KR294_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosyltransferase family protein"
                     /protein_id="HBH0240752.1"
                     /translation="MKNCLNFNCEIDIIDNPLNLELNDFLDVGIRNNSKRRFLFISKK
                     LGKHLACKPSEMDNLGKLMATIYNEKNKEESNGTVIAFAETGTAVGHSFFDYLCGDYE
                     FIHTTREQFDELENLEFLEEHSHATDQNLYFGMLNNFKFGDEIILVDDEITTANTCMN
                     IIRKIQSIYPKKKYTICSILNWVSDENLSKVTRLERELDCKIDFVYLFKGNFKFYIDE
                     DIISNYNDNYSITKLETISSDKVNLVVNHIYVDLEDYIGNKKYVKYTGRFGINRREQF
                     RLKEIVKRESKKITMASKESLKNEKEKILFLGTEEFMYIPMLFAKEKENQYDIYYHST
                     TRSPIINIDKNNYPIKSKFMLKSFYNIDIQNYIYNIDKHNFSKCYLFVELNKSENSYL
                     EFIDIIKKTSIKELTIVCCS"
     gene            10180..11268
                     /locus_tag="KR294_002688"
     CDS             10180..11268
                     /locus_tag="KR294_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine protease StiP family protein"
                     /protein_id="HBH0240753.1"
                     /translation="MRDFSTYSKDDVIFLLKDISNLIEEEGNKERELKIQNGRHYSEM
                     IPIEYEVSEDYLNLYHEKLRENKDKLAFSIGVMCEKIIKKNGNDVVLVSLARAGTPIG
                     ILAKRYIRSKYNVSLPHYTISIIRDKGIDMNAIEYIVKNHPSSKIQFLDGWTGKGTIS
                     KELEKACDELNVKFKKYFDSTLAVLADPAGYSGLYGIREDFLIPSACLNSTVSGLVSR
                     TVLREDLISKNDFHGAKFYRHLKDKDESMNYIETIEECFKNQFKNISDEVENWESDII
                     TRDGYFDVLNIKEKYNITDINFIKPGVGETTRVLLRRVPYKILVKDLNDKSLDHIFIL
                     AKEKNVEVEQMDLKAYKCCGIIKNMKDI"
     gene            11296..12087
                     /locus_tag="KR294_002689"
     CDS             11296..12087
                     /locus_tag="KR294_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HBH0240754.1"
                     /translation="MIVFSDLDRSIIYSNKFLNADSKYANIEIYREKEISYISLDTIN
                     LIKQIQYYGMFIPTTTRTVEQFKRIEFNKYGIYFPWSITSNGGVILKDNEILKSWSEK
                     IDKLKSDYEPIESMIHKFKDYLNVDGITNFKVAEDTFFYIVVDLSRFNLDSIKEYTNI
                     LESKNWKFYVSGRKIYFIPKEISKENAIKYLTKELGIEYFYAVGDSIMDYGMLNISNK
                     SYVLKHGDINKNEIENSFISSSFNGMSGTEEILSNILDENCLLNI"
     gene            complement(12202..12756)
                     /locus_tag="KR294_002690"
     CDS             complement(12202..12756)
                     /locus_tag="KR294_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HBH0240755.1"
                     /translation="MNIDVGSKIRSLRKSKNISISTLAKNSDLSTGLISQIERNMVVP
                     SIVAMWKISKALDINIGYFFEEIGREDSDIVVKKNNRKKIVTNDSTKFYELLVPNLSG
                     KKIEFILVTLDGHTHKNSEFVTHEGEECGYIIKGKMKITLGNKEYLLEEGDSFYFNST
                     IPHVYENYDDEVCISVWAMTPPSF"
     gene            12952..14154
                     /locus_tag="KR294_002691"
     CDS             12952..14154
                     /locus_tag="KR294_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF819 domain-containing protein"
                     /protein_id="HBH0240756.1"
                     /translation="MKSFVSPDNIWVLWAVVTGWAAFSIYLEQKYNWASKVSGAIIAL
                     VGAMLLSNLNIIPVESVVYDQVWGYVVPLAIALLLYQCNIKKIWKESGRLLIIFLVGS
                     VGTVLGAMIGFLALKNVVPDLNIVAAMMTGSYIGGNVNFAAMSGAFDAPGELVSATVV
                     ADNLLMALYFFVLIAIPSIGFFRKHFKHPHVDEMESIGITEGETVAANYWGRKEISLK
                     DIAIAIGSAFIIVAVSVELSTWFKAIIPLSNPFLAMLNTLFGNQYLIITTLTMLFATF
                     MPNFFGDIKGAQELGTFLIYIFFVVVGVPASITLIIQKSPLLLLYCGIMVLINMLVTF
                     IVAKIFKFSLEEAILASNANIGGPTTAAAMAISKGWSKLVGPILIVGTFGYIVGNYFG
                     LLVGNILI"
     gene            14211..15191
                     /locus_tag="KR294_002692"
     CDS             14211..15191
                     /locus_tag="KR294_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HBH0240757.1"
                     /translation="MIFDGHSDTWADVTIRRLNGEKDVFRRIHLDNFKRANIEGAIFV
                     IWIDPPYDKEPEKRVKQIISSIKDEIEDMKDVVNIVKKYSDIDKGISENKINILIGLE
                     GLSHIGRNIDLLDYFYKEVGARHASLTWNEQNELATGCLGDENRGLTEIGKKAVNKME
                     KLGMIVDVSHLNEKSFWDLMSVASKPVIASHSNARSLCDAKRNLTDNQLKEISNTGGL
                     VGINSFRGFTNSNPKKQDLIHLVDHIDYMVNLIGIEHVSFGFDFSDYLGKETIGSFTG
                     NASVPSVDGLESTHTAQNIVVELENRGYKKKDIELISSGNFYRLFKDILK"
     gene            15439..16392
                     /locus_tag="KR294_002693"
     CDS             15439..16392
                     /locus_tag="KR294_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HBH0240758.1"
                     /translation="MKKRYLVIGIIILSYFSLFIGAEDINIMHIFAKNQHKLMIFIMS
                     RIPRLISILIAGVGMSIAGLIMQQISKNKFVSPTTGATIDAAQFGIVICMLLVPTASI
                     FTKTIIAFVFSLVGTFTFMKIIGKLQFKNIIFVPLVGIMFGNIIGSMTDFIAYKYDLS
                     QNVSSWMQGDFSMILKGNYEILYITIPLIILAYIYANKFTVVGMGMDFATNLGLSYKR
                     IVNIGLIIVALVTVCVVVTAGNIPFIGLIVPNIVSLYMGDNIRASIWYTGLLGAIFVL
                     ICDIFGRIIIYPYEISIGLTVGVIGSILFLYLILRRNVNEA"
     gene            16382..17338
                     /locus_tag="KR294_002694"
     CDS             16382..17338
                     /locus_tag="KR294_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HBH0240759.1"
                     /translation="MKLSLNQKIYFVSILLFISIALFIIYGIDMNHLEYALSQRIPKI
                     FAMVLGGGCIAFTTVVFQTITNNQILTPSVLGLDSLYVMIQTIIVFIFGSSSSLIINE
                     NYNFIINVAMMIGASLLLYKTLFEKNKNNIFFLILVGMIFGTLFKSATTFIQVMIDPN
                     EFLALQTSIMASLNNINTNVLLIAFIIIIAIIPFIYDEIKYLDVLSLGKEQAINLGVD
                     FDKAVKKMIILIAILVSISTALIGPMTFLGLLLANITREIFKTYKHTYLISGSMLIGM
                     ITLIIGQFFIQHVFKFDTTLSVVINFIGGIYFIQLLLKGANR"
     gene            17335..18090
                     /locus_tag="KR294_002695"
     CDS             17335..18090
                     /locus_tag="KR294_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH0240760.1"
                     /translation="MIEIKNIFKRYKNKNVVDDVSFSIEKGKITSFIGPNGAGKSTVL
                     SIVTRLIGGDGGEVIIEGKSLTNYSNKELAKKIAILKQSNNITLKLTIRELVGFGRFP
                     YSEGNLTKEDENYIDEAIEYMKLTDIQHKYLDELSGGQRQRAYIAMVIAQDTEYILLD
                     EPLNNLDMNHSVQMMKVLRSLCDELDKTIVLVMHDINFASCYSDNIVALKNGKVKKVG
                     RTDEIVNEKVLEDIYEMNFNIKNINGNRICIYF"
     gene            18182..19147
                     /locus_tag="KR294_002696"
     CDS             18182..19147
                     /locus_tag="KR294_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HBH0240761.1"
                     /translation="MNKKAAIVAAVAIIGLVTVFALGGSKKNESKTSENSNNTMKITH
                     NLGETDVKLNPKKVVVFDYSALDTMDALGVAENLVGLPKASLPASLEKYKDDKYADLG
                     GLKEPDLEGIKSANPDLIIINGRQEDFYEQLSKIAPTISTSKDDKKYLESVKNNIDKI
                     AKIFGVEEKANQEFSKIEKKIETLNKKVTDKNLNALTIMVNEGNLSVFGEESRFSILY
                     NSFGFENKDKNIKESSHGQNITFEYIAKQNPEVMFVIDRGIATGSDVKESSTAKSVLN
                     NDIIKSMDAYKNDNIIYLDSPTWYVNDGGLTSLNKMIDDASKAVN"
BASE COUNT         7711 a         1961 c         3431 g         6301 t
ORIGIN      
        1 tttctcctat aataagatga tataatctat tataaaacaa cttaaaacaa tatagtacaa
       61 taattttgta gtttcaaaat aaaatatgta cttgtttata taaatgatat ataattacat
      121 attaaacata gcttttatgc atttaataaa gtatgtaaaa tctatgtaaa aagtaagaaa
      181 tataaacatt tttttaatta tattttaaaa atatcaagca agttttattc acaaatgaat
      241 aaaaaatgtt ataatatgat taaagaaaaa gataaataat tagcaagatt tgtttagcta
      301 aaattaacaa gggagcgata aattatgggt ataacattat caaaaggcca aaaggttgat
      361 ttaactaaag gaaatccagg tcttaaaaat attttagtag gtttaggatg ggatactaac
      421 aagtatgatg gtggatttga ctttgattta gatacagcag catttttaac aggagcaagt
      481 ggaagtgtta ctaatgatgg agattttgta ttttacaaca atttaaaaca tacatctgga
      541 gcagttgagc atctaggaga taacagaact ggcgaaggtg atggagatga tgaacaaata
      601 gttgttgatt tatctaagat tcctggagaa ataagcaaga tttcttttac tgttacaatt
      661 catgatgcaa cagaaagaag acaaaatttt ggacaagtaa gtaattctta tataagaata
      721 gtagataaag acacaaatga agagttaata aagtatgaat taggagaaga ttttagtata
      781 gaaacagcta tagtagtagc tgaaatatat aagcacaatg gagaatggaa gtttaatgca
      841 ctaggttctg gctttgaagg tggtcttgct gcattatgtg gaaactttgg aataaactta
      901 taatttcaac tataacaata aactaaaggg ggatattttc catggctata gtattaaaaa
      961 aaggacaaaa aatcgattta actaagggaa atccaggtct taaaaatata aaacttggac
     1021 taggatggga tacaaattca tttgatagtg gctatgatta tgatttagat gtaagtgttt
     1081 tcatggttgg agaatctcaa agagttgaaa aagatgaaga ttttatattc tacaataact
     1141 taaaacatcc atctggagca gttgaacact taggtgataa tagaactggt gaaggtgatg
     1201 gagatgatga ggaaatatta gtgaatttag agacaatgcc aaagcatata caaaagatag
     1261 ctgtaacagt tacaatatat gaggctgctg aaagaagaca aaattttgga caagtaagca
     1321 actcatatat aagagtatta aattctgaaa atgatgaaga aatattaaga tatgacttag
     1381 gtgaagaatt tagtatagaa actgcaatta cagtatgtga gatatataag tataatggag
     1441 aatggaagtt tagtgcagtt ggagcaggat ttgaaggtgg cttagaagca ctttgtagaa
     1501 actatggctt aaatgtttaa tttaagcaat ataatatatt aaatataaat aacctataca
     1561 aataatgtat aggttatatt atataaaatt ttgtggaggt ttagtatgtc gattaattta
     1621 tcaaaaggtg ataaaataga tttaaaaaaa tctaacccag gactgagtaa catacttgta
     1681 ggtctaggat gggaccctgt gcaacaatct ggcggaggtt tttttaaatc gttatttggt
     1741 ggaggacaag ctgatataga ttgtgatgca tctgtattta tgcttaatca agaaggtaaa
     1801 ttaagtggaa taaaagattt aatttatttt ggaaatctaa aaagtgcctg taaatcagtt
     1861 ttgcatacag gagacaatct aactggtgag ggtacaggtg atgatgaaca aatcctagtt
     1921 aatttggata aagttccatc aaatattcat aaattattgt ttgtagtaaa tatatacaat
     1981 tgtgtagata gaaaacaaca ctttggaatg atagaaaatg cctatataag agttgaagac
     2041 caaggtaata agaaagagat agcaaaatac aatctatctg ataattattc tgaaaaaact
     2101 actcttatag taggagctat atatagaaaa gatggaagtt ggcaatttaa agcaattggt
     2161 gaaggaacaa aagatgcggg tcttaaagaa gtaatgcaaa atttagacag gattgagtgt
     2221 gcatatggaa tttaataatg atatcaaata ttataatgta gataaagaag aagttacaaa
     2281 agacttatct gttaatcctg aaaaaggttt atcagaatca gaagtcaaga ctagaagaga
     2341 aaaatatggt ttgaatgaat ttactccaaa agaagagggt agtttttggg atgatttaaa
     2401 ggaaagttta agtgaaccaa tgatagttat cttgattatt gcagcagtag taagtgcagt
     2461 aattggggaa actcatgatg caatagggat tgtaggtgct atagcaatag gtatagcaat
     2521 aggtatgatt acagaaggtc gttctaagaa agcagcagag gctctttcta agttgactga
     2581 aaacatagaa gtaaaagtat tgagagatgg ggaagtacat caaatttcta agagtgaatt
     2641 ggtaccaggt gatatagtat atattgaaac tggtgacatg gtacctgctg atggtagact
     2701 tatagaaagt ataaacctta aaattagaga agatatgtta acaggagaat ctgatgacgt
     2761 atctaaaaag tgtgatgtag tagtttctat ggaagagata gaatctaaag gagcagtagt
     2821 agtacaggaa ccaatacctg caaaacagat aaatatggtg tttggtggta cacttgtagc
     2881 ttatggtaga ggagctctag ttgtaacttc aattggagat aatagtgaaa tgggtaaaat
     2941 tgctcaaaac ttatcagaaa cagatgagca aactccactt cagataaaac ttggaaattt
     3001 aggtggtttg atagccaaag tttctagtgc agtagcagga ttactattta tatttatggt
     3061 tttccaaatg ataagtaaga atgtattaaa tgtagatatg tctggaatat taccgttttt
     3121 agaatcaata gacccagtta aaacagcatt tacagtatgt gttgcgttga tagttgcagc
     3181 agtgccagaa ggtcttccaa ctatgataaa tatgacactt gcaataacaa tgcaaaaaat
     3241 ggctaaaata aatgcattgg ttaccaaaaa agaagcttgt gaaacgatag gttctgtttc
     3301 tgtaatatgt tcagataaaa ctggtacatt aactgaaaat agaatgactg tagaagttgc
     3361 atatgttgat ggcagatata ttgaaagttc agaagaggaa ataaatagtt attttgaaga
     3421 aaactgtatg ataaactcta cagctgatgt agagcacaat gatggtgata ttaagtattt
     3481 aggaagtgct actgaatgtg cattgctttt atattacaaa aacgtagatt atagacaagt
     3541 tagaaaaaat tctaatatag tagctcaaaa tccttttact tcagattcaa agagaatgac
     3601 ttctgttata ggtcaagata atcatcatgt actattatca aaaggagcac cagaagtctt
     3661 acttgaatta tgttcacata ttcaaagagg aaaagacata gttccattaa ctgaaaatat
     3721 aaaacatgag attttagaag aaataaagaa attgcaaata aaatcaatga gaactttagg
     3781 gtttgcatat aaagaaatct cacaagctga agaagaagca gcagtaactg ctgaaagtga
     3841 tgctatgaat gtaagtgcaa tggaaaacaa tttagtattt agtggttttg ttggtataag
     3901 agacccactt agaaaagatg ttatagagtc tgtaaataca gcaaataaag ctggtgtttc
     3961 tgtaaaaatg cttacaggag ataatataaa tacggcaaga gctataggtg aagagttagg
     4021 cctattaaaa aataatatga gagtggttga agcttcatat atagatactt tagatgatga
     4081 agaattaaaa caagagatac aaagtatttc aatcgtggca agaagtaaac cagatagtaa
     4141 aatgagaata gtttcagctc tgcaaaagag cggagatgtt gttgcagtaa caggtgatgg
     4201 tataaatgat gctccagcac tttcaaaagc agatgttggt atagcaatgg gtatatctgg
     4261 tacagaggta tctaaaaacg cagcagacat aattttaact gatgatagtt ttagtaccat
     4321 tgtaaaaggt attaaatggg gtagaggaat ttatgataac ttccaaagat tcgttcaatt
     4381 ccaattaact gtaaatgtaa ttgcattttt agtggctata atatctcaag ttatgggaca
     4441 agagatgcca tttactacaa tacaattatt atgggtaaac atcattatgg atggaccacc
     4501 agcactagca ttaggtttag agccagttag ggaccatgtg ttaaacagaa aacctgttga
     4561 tagaaaagcc aatataattt ctaagtcaat ggtgtataca atagtattaa atgcatttta
     4621 tataacagca atactaatgt tacaatctac atttaatttc ttaggagttg atgaagcgca
     4681 taagggaaca gtaatgtttg cgttatttgc ttttagtgca ctgtttaatg catttaactg
     4741 tagagagttt aatgcagata gtatcttccc taattttaca cataacaaat tagcactaca
     4801 aataatagtg ttgacaggaa ttgcacaagt aatatttact cagctattcc aagatttctt
     4861 taactctgta gcaatggatt ttatgacatg ggtaaaagtt ttatgtgtag cagcaagtgt
     4921 aattgtggtt aatgaagttg taaaatgtat aataagactg gtaaaaccaa aaaagactgc
     4981 ttaaaacaaa ttttttagaa gaaaacagac tgactcaaaa tatgaatttt gggtcagttc
     5041 tgaataaaca tttaaattgg gaggatagtt atgggtgact caaaggtatt tgaaaaaata
     5101 ttctccagcc aatcagatag aggaaattac actccttcaa agggatatct aagttatttt
     5161 atttcgtata ttggtttaga agatgaagtt ttgtacaatc tcgagatatt taaaacaaaa
     5221 caaaatattg atagcaaaaa agatattgct ttatttactg atgttatagc aaatcctagt
     5281 gattttgata ttataaatta ttttaaaagt ggacttcaaa aatatagaac tagcatggaa
     5341 gatgtagata taaatatttt gggatttgaa gagattgatt ataaaataaa gcaagcaatg
     5401 gatagagtgt taaaagaaga ggaaaaagaa tttactaatg atagagttaa acaaaatttt
     5461 atagtgaaaa taatggcatg gataaaaatt tatatcggtg ctttagatat aaataaaaat
     5521 gaagctccaa aagtaatatt ttatggagat ataaaaaaac atgaagttta tttactctta
     5581 atattatact tggcaggttt tgatgtttta tatcttaatc caaattcaaa gagtaatata
     5641 gatattttaa aatcagaaag atacaatata gagtttgaag aagccaacat aatagaagaa
     5701 aaaatttctt ttgaagaaag ggttatttta ggggaaaaaa tagataaaag ttctgtaaaa
     5761 aaagctttta ctgttggggc agaagcatca aagcgtataa gtgaggaatt gttaaatgat
     5821 gcaggattta taaaaccttg gcaactccaa gatagaaaaa taaaaaatct acttctaagt
     5881 tcaactgttg atgaaatatc aatatactgg aatcaaccac ttaaattaag accaggattt
     5941 aagtttaatg atgctattgt agaagctcca aattttcttt ctaagattaa tggaatatat
     6001 aacgataaga atgaatatat taagttttta gatttattaa gagattcgga aagttcaaca
     6061 tttattgaat ttaatggaga tgtagataga ttttcaaaag cttttacaag agaagctttt
     6121 agtttatcct ttttattgga ttcaaaaggt gcaatagata aaaactctgt tttaaataat
     6181 aaagattatt ccatatcaac attagcattg aatcaacaaa ttatgatttt agagaaagtg
     6241 gaagagttgt tagaaggaag tatgtttttg aatggtttaa gtggagaaga caagataaaa
     6301 ggtctattta cagtacttca catggataag aaatttgttc atatgatgaa caatttcgat
     6361 tactcactta taaacccaaa attgattata tacatgtaca agagtattgt atttgataaa
     6421 gaaatagttt ttcttatgct tttacttagt aagattggat ttgatattat catattatgt
     6481 ccaggaggag aaaacaatat agagaatgtt ataaataacc aattgattga tgtacacaga
     6541 ttggataaaa tggtatatga ccttaaatta aattcgcttg aaaatgatat acctttactt
     6601 aaaaaaattt ttggaaagag gagacgattt tagatgggga taaatataaa tagtttttca
     6661 aaagataaga actctgtaga ggttactgag aatttgccta cagcagttca agaagaaaac
     6721 ttcgatataa tggaatatac aaataataaa aaaaatgaac tgagaaagtc taaggaagtt
     6781 gaggcattga catctcttat agaagtagaa aatccagata cgattttaca gtttggtagg
     6841 aaagcatctg aaggagtagc aagagtttct gatagccttt taaatacaat aaaattaaat
     6901 agaaatgaag aaaattctaa aatgctggtt catttaacta aaataatgga caagtttgat
     6961 ttagacgatt ttcaagaaac taaggaacca aatttcgttc aaaaactttt caaaaaagct
     7021 aataatgcca ttgaaatgat gtttcaaaag tatgaaacat tgggaggaga agttgagaaa
     7081 attcaaattg agcttgaaca atacgaaaga gatatagcac tttctaataa gcaaataggt
     7141 gctatgttaa atgaaaactt tgagttttac aatgaacttc aaaaatatat tgttgctgga
     7201 gaaatggcaa tagaagaaat ggataatgaa atactacctt tctttaaaca aaaatcagag
     7261 actagtggag accaaatgga tgttgtcaat tatcaagaac tattaaaagt ttatgatatg
     7321 ttaaatcaaa gagtctatga tttaaggata gcagaaaata tagctatcca aacaatacct
     7381 atgcttagag gtatgcaaca taataattat ggtttaatta gaaaaataaa tagtgcattt
     7441 gtcgtaactt taccagtatt taaacaatgt ttatctcaag ctatattact taaaaagcaa
     7501 gaattacaag caaaatctct aaaagcactt gatgacaaaa ctaatgaatt attgcttaga
     7561 aatgcacaaa atgtaagtac tcaaagtgca caaatagcta gaatggctgg aacaagttct
     7621 gttcaaatag aaacattgga aaaaatgtac aatactatta aatctggtat agatgaaact
     7681 atgagaatag aagaaaacaa tagagcttta attaaggata atacaaagag attggaagaa
     7741 ttaaatacga ctataattta taataagtag tattatatta agggctaatt tgtataaagt
     7801 tggccctttc tatgtatatg aggaggctag acattgaaat atttcgatta tatctgcaaa
     7861 gatgatttgg agagaatttt tttgaaggag ccagaagatt ttagtgctaa gactgaaaaa
     7921 gatgtgttga aatatgcact gggcgctttt ttatacgttc cagctactca atataatatg
     7981 atttataaga gtattatagg ggatgttaag ggagttagac cattagctat ttgtttagaa
     8041 gatgctgttg gagtaaatgg agagttagag gctatagaaa atcttagatt aattttaaaa
     8101 aatattagca atgaaagtat aactaataaa gatggaatac cactaatttt tgtaagaata
     8161 aaagatgtgg agcaactgtt gagaattaaa gagattataa ttaaaaatag acattctata
     8221 acaggaatat taattcctaa agcaaattcg gagttaatag aaaattgtat agaagcttta
     8281 gattctatga atcttcaaga tatgtatgtt attccgataa tagagacaaa agaatttata
     8341 tataatgaaa aaaaagaact tagttttact aatttgtaca atgctatttt aagacataag
     8401 tcaagaatat taagcattag agtaggcata actgatatat tagggatgta tggtataagg
     8461 agagataaga acttctctat atataataat ttgatttgtt cttcatttat attagatata
     8521 atcacatatc ttcaaagacc agagttagat atacctataa gtggtggagt atcagaattt
     8581 tttgatatga cgaataagga tataagaaat aagtatatag aagaaatatt attggataaa
     8641 tatcatggat taattggaaa gaccgtaatt catccaatgc aaattcaaat tgtacaagcg
     8701 ctatctacag tatcatatga agattttact gatgctttgg atatactgga tagtacagac
     8761 agtaagtatg gtgtgagcaa gggtgtatta ggagagagaa tgaatgaaac aaatccacat
     8821 tttttatggg ctaaaaaaac attgattcta tctaaaatat atggtgtatt aaataaagga
     8881 gtagactatg aagaattgct taaattttaa ttgtgagatt gacattattg ataatccatt
     8941 gaatttagaa ctaaatgatt ttttagacgt aggaataaga aataatagca aaagacgttt
     9001 tttgtttatc tcaaagaaac tcggtaaaca tttagcatgt aagccaagtg agatggataa
     9061 tttgggaaaa ttaatggcta caatttataa tgaaaaaaat aaggaagaat caaatggtac
     9121 tgttatagct tttgctgaaa ctggtacagc tgttgggcat agtttttttg attacttatg
     9181 tggagattat gaatttattc atactactag agagcagttt gacgagttag aaaatctgga
     9241 atttttagag gaacattccc atgcaacaga ccagaattta tactttggta tgcttaacaa
     9301 ctttaaattt ggagatgaga taatattggt tgatgatgag attaccacag ccaatacatg
     9361 catgaatata attaggaaaa ttcaaagcat ttatcctaaa aagaaataca ctatatgctc
     9421 aatactcaat tgggtaagtg atgaaaattt aagtaaagtt actcgtttag aaagagagct
     9481 agattgtaag atagattttg tatacttatt taaaggaaac tttaaatttt atatagatga
     9541 agatattatt tcaaattaca acgataatta tagtattact aaattagaga ctatttcaag
     9601 tgataaagta aatttagtag taaatcatat ttatgttgat ttagaagatt atattggaaa
     9661 taagaaatat gtaaaatata caggaagatt tggaattaat agaagagaac aatttagatt
     9721 aaaagaaatc gttaagagag aaagtaaaaa aataactatg gccagtaaag aatctttaaa
     9781 aaatgaaaaa gaaaagattc tatttttagg tactgaagaa tttatgtata tacctatgct
     9841 gtttgcaaaa gaaaaagaaa atcaatatga tatatactat cattcaacaa caagaagtcc
     9901 aattattaat attgataaga ataattatcc tattaaaagt aaatttatgc taaagagttt
     9961 ttataatata gatattcaaa attatattta caatatagat aaacataatt tttctaagtg
    10021 ttatttattt gtagagctga ataaaagtga aaattcttat ctagaattta ttgatataat
    10081 taaaaaaaca agtataaaag aattaactat agtatgttgt agctaaagtg ttttaacagg
    10141 ataaaatata tcacgatttt aagataggag ttgagtcata tgagagattt tagcacgtat
    10201 tctaaagatg atgttatttt tttattaaaa gatatatcaa atttaattga agaagaagga
    10261 aataaagaaa gagaattaaa aatacaaaat ggtagacatt attcagaaat gataccaata
    10321 gagtatgaag ttagtgaaga ttatctgaat ttatatcatg agaaactaag agaaaataaa
    10381 gataaacttg cattttctat aggagttatg tgtgaaaaaa taattaaaaa aaatggaaat
    10441 gatgtagtac tagtttcact tgctagagca ggaacaccta ttggtatttt ggcaaaaaga
    10501 tatataagaa gcaagtataa tgtaagttta cctcactata caatctctat aataagagat
    10561 aagggaatag atatgaatgc aattgaatat atagtaaaga atcatccgag ctcaaaaatt
    10621 caatttttag atggatggac tggtaaagga actatatcaa aagaacttga aaaagcatgt
    10681 gatgaactta atgttaaatt taaaaaatat tttgactcaa cacttgctgt attagctgac
    10741 cctgctggat attcaggact ttatggaatt agagaagatt tcttaatacc aagtgcatgt
    10801 ttaaattcaa cagtttctgg tttagtaagt agaactgtac taagagagga tttaattagt
    10861 aaaaatgact ttcatggagc taagttttat agacatttaa aagataaaga tgaatctatg
    10921 aactatatcg aaactataga agaatgtttt aaaaatcaat ttaagaatat atctgatgaa
    10981 gttgaaaact gggaaagtga cattataaca agagatggat actttgatgt tttaaatata
    11041 aaagaaaagt ataacataac agatattaac tttatcaaac caggtgtagg ggaaacgact
    11101 agggttttac ttagaagagt tccgtataag attcttgtta aagacttaaa tgataaatct
    11161 ttagaccata tattcatatt agctaaggag aaaaatgttg aagttgaaca aatggattta
    11221 aaagcctata aatgttgtgg aataataaaa aatatgaaag atatttagga aatatattag
    11281 acaggagaat attgaatgat tgttttttca gatttagaca ggagtatcat ttactccaat
    11341 aaatttttaa atgctgatag taaatatgct aatatagaaa tttataggga aaaagaaata
    11401 tcttatatat ctttagatac tataaattta ataaagcaaa tacaatatta tggtatgttt
    11461 atacctacaa ctactagaac agtggagcaa tttaagcgta tagaatttaa taaatatggg
    11521 atttattttc cttggagtat aacttcaaat ggaggagtta tacttaaaga taatgaaata
    11581 ttgaaatcat ggagtgaaaa aatagataaa ctaaaatctg attatgagcc cattgaaagt
    11641 atgattcata aatttaaaga ctatttgaat gtagatggaa taactaattt taaagttgca
    11701 gaagatacat ttttttatat agttgttgat ttatcaagat ttaatttgga ttcaatcaaa
    11761 gaatatacaa atatattgga atcaaaaaat tggaagtttt atgtgagtgg cagaaaaata
    11821 tattttatac caaaagaaat ttcaaaagaa aatgctataa aatacttgac taaagaatta
    11881 ggaatagaat atttttatgc agttggagat tctattatgg actatggtat gcttaatatc
    11941 tcaaataaat cctatgtatt gaagcatggt gatataaata aaaatgaaat agaaaattca
    12001 tttatatcaa gttctttcaa tggaatgagt ggaactgaag agatactatc taacatttta
    12061 gacgagaact gcctacttaa tatataatga ctgatatata aataataaac tagaaaaatc
    12121 tgaaataaat tatagtaaag tttatcatac taatttattt cagattttta tcaatttata
    12181 tttaagtaag aactcaatat gttaaaatga aggtggagtc attgcccaga ctgagataca
    12241 tacctcatca tcataatttt catacacatg tggtatagta ctgttaaaat aaaaactatc
    12301 tccttcctcc aatagatatt ccttatttcc aagtgttatc ttcattttac cttttattat
    12361 atagccacat tcttctcctt cgtgtgtcac aaattcactg tttttgtgtg tatgaccatc
    12421 tagtgtaaca agtataaatt ctattttttt cccagataaa ttaggaacaa gaagttcgta
    12481 aaattttgta gaatcattag ttactatttt ttttcgatta tttttcttta ctactatatc
    12541 agagtcttct cttccaatct cttcaaaaaa ataacctata tttatatcaa gagcttttga
    12601 tattttccac attgctacaa tagatggaac aaccatatta cgctcaattt gacttattaa
    12661 gcctgtactt aaatctgaat tttttgctaa agtagagata cttatatttt tagattttct
    12721 aagagatcta attttgcttc caacatctat attcattaga tacaaacccc ctcagacatg
    12781 attataacat ataatttata aagattaata aaataaaaaa aaagttttac aatacaagta
    12841 ttttttatgc tatattgaat tttctgaaaa gatgcattat aatagtatta atattcaata
    12901 tattgaatat tgataacgat attttaattt aatgaaatgg aggtaattaa gatgaagagt
    12961 tttgtaagtc ctgataatat ttgggtatta tgggcagttg taactggatg ggcagcattt
    13021 agtatttatt tggaacaaaa gtacaattgg gcatcaaaag tgtcgggagc aataatagct
    13081 cttgtaggag caatgttatt atcaaatcta aatattatac cagtagagtc tgttgtatat
    13141 gaccaagtat ggggatatgt tgttccttta gccatagctt tattgttata tcaatgtaac
    13201 attaaaaaga tatggaaaga aagtggaaga ttgctcatta tatttcttgt aggttctgta
    13261 ggaactgtac ttggagctat gattggattt ttagcattaa aaaatgtagt accagattta
    13321 aatattgttg cagctatgat gacaggttct tatataggtg gaaatgtaaa ctttgctgct
    13381 atgtcagggg cgtttgatgc gccaggagaa ttagtatcag caacagttgt agcagataat
    13441 cttttaatgg cattatattt ctttgtctta atagctatac catcaattgg attttttaga
    13501 aaacatttta aacatccaca tgtagatgaa atggaaagta taggtataac tgaaggagaa
    13561 acagtagcag caaattattg gggaagaaaa gaaatatctt taaaagatat agcaatagcc
    13621 attggtagcg cttttataat tgtcgcagta tctgtagaac tatcaacttg gtttaaagct
    13681 ataataccat tatcaaatcc ttttttagca atgttaaata ctttatttgg aaatcaatat
    13741 ctaataataa ctactttgac tatgttgttt gccacattta tgcctaattt ctttggtgat
    13801 ataaaaggag cacaggaatt gggtacattt ttaatatata tattctttgt tgtagtaggt
    13861 gttcctgctt caataacatt aataattcaa aaatcaccat tactactttt atactgcgga
    13921 ataatggtac taataaacat gctagttaca tttatagttg caaaaatatt taagtttagt
    13981 ttagaagaag ctattcttgc atctaatgca aatattggtg gtcctacaac agcagcagct
    14041 atggcaatat caaaaggatg gtctaagcta gtagggccaa tacttatagt tggaacattt
    14101 ggatacatag tcggtaatta ttttggtctt ttagtaggaa atattttgat ataattttac
    14161 gtgaaaaaaa gttgtttttt agaaagattt ttatttaatt ggaggttgtt atgattttcg
    14221 atggacattc agatacttgg gcagatgtaa caataagaag gcttaacggg gaaaaagatg
    14281 tatttagaag aatccatctt gataatttta aaagagcaaa tatagaagga gctatttttg
    14341 taatatggat agacccacca tatgataaag agcctgaaaa aagagttaaa caaattataa
    14401 gctctataaa agatgaaatt gaagatatga aagatgttgt aaacatagta aaaaaatatt
    14461 cagatataga taaaggtata agtgaaaaca aaataaatat tttaattggt cttgaaggat
    14521 taagccatat tggaagaaat atagatttac tagattattt ttataaagaa gttggtgcaa
    14581 gacatgcatc attaacttgg aatgaacaga atgaacttgc tacaggatgt ttaggggatg
    14641 aaaatcgtgg tttaactgaa ataggtaaaa aagcagtcaa taaaatggaa aaattgggca
    14701 tgatagtaga tgtgtcacat ttaaatgaaa aatcattttg ggatttaatg tctgttgcaa
    14761 gtaagccagt tatagcttct cattctaatg ctaggagttt atgtgatgct aaaagaaatc
    14821 ttacagataa tcaattaaaa gaaatttcaa atacaggtgg attagttgga ataaatagtt
    14881 ttagaggatt tactaatagt aatcctaaga agcaagattt aatacatttg gttgaccata
    14941 tagactatat ggtaaatctt ataggtatag aacatgtatc ttttggtttt gattttagtg
    15001 attacttagg gaaagagact ataggttctt ttactggaaa tgctagtgtg ccaagtgtag
    15061 atggtcttga aagcacacat acagcacaga acatagtagt agagcttgaa aatagaggtt
    15121 ataaaaagaa agatatagag ttaatctcta gtggtaattt ttataggctc tttaaagata
    15181 tactaaaata atataataaa gaacttaaat ttataaaata gtatatttat acaaataata
    15241 tctacatatt taaattggcg ttcataattt attaaattaa attttaatgt tactagaagt
    15301 ttcaattcta gtaacatttt ttatgttaaa aacagatata gatatatatt gacaatgata
    15361 attattattg ataaactata aaagtgaaaa tgataataat tttcatttta attaataaaa
    15421 gatttttaag gagggagaat gaagaaaagg tatttagtca taggaataat aattttgtct
    15481 tatttttctt tatttatagg agctgaagat ataaatataa tgcatatatt tgccaaaaat
    15541 cagcataaac ttatgatatt tatcatgagt agaataccaa gattaataag tatattgatt
    15601 gctggtgtag gaatgagcat agcaggtctt ataatgcaac agataagtaa gaataaattt
    15661 gtatcaccta caacaggtgc tacaatagat gcagcacaat ttgggatagt aatatgtatg
    15721 cttttagtac caactgcctc tatttttaca aagacaataa tagcatttgt attttctctt
    15781 gtagggactt ttacgtttat gaaaataata gggaagttac aatttaaaaa tataatcttt
    15841 gtaccattag taggtataat gtttggaaat ataataggtt ctatgacgga ttttatcgcg
    15901 tataaatacg atttgagtca aaatgttagt tcttggatgc aaggtgactt ttctatgata
    15961 cttaaaggaa attatgagat attatatatc acaatacccc ttataatatt agcatatatt
    16021 tatgcaaata aatttactgt tgttggtatg ggtatggatt ttgcgacaaa cttaggtctt
    16081 agttacaaaa gaattgtcaa tataggtctg ataatagtag cacttgttac agtatgtgta
    16141 gtcgttacag ctggtaatat cccttttata ggtctaatag ttcccaatat cgtatccttg
    16201 tatatgggtg ataatataag agcaagcata tggtatactg gtttacttgg agcgatattt
    16261 gtacttatat gtgatatttt tggaagaatt attatttatc catatgaaat atctataggg
    16321 cttacagttg gagttatagg aagtatacta ttcctttatt taatattaag gaggaatgta
    16381 aatgaagctt agtctcaatc aaaaaattta ctttgtaagt atattactat tcatatcaat
    16441 agcacttttt ataatttatg gaatagacat gaatcattta gaatatgcat tatcacaaag
    16501 aataccaaaa atatttgcta tggtattagg tggaggatgt atagcattta ctactgtagt
    16561 gtttcaaaca attacaaaca atcaaatatt aacaccaagt gtactaggtt tagattcatt
    16621 gtatgtaatg attcaaacta taatagtatt catatttggt tcaagcagta gtctgattat
    16681 aaatgaaaat tataatttta ttattaatgt agctatgatg attggagctt cattgttatt
    16741 atataagacg ttatttgaaa aaaataaaaa taatattttc tttttaatcc tagtaggaat
    16801 gatatttgga accttattta aaagtgcaac aacatttatt caggtaatga tagaccctaa
    16861 tgaattttta gctttacaaa ctagtataat ggcaagttta aacaatataa acactaatgt
    16921 attgttaata gcatttataa taattattgc cataatacct tttatatatg atgaaataaa
    16981 gtatttagat gtattgtcgt taggtaaaga acaagcaatt aatttaggtg tagattttga
    17041 taaagcagtt aaaaaaatga taatattaat agcaatttta gtctcaatat caacagcact
    17101 tattggacct atgacatttt taggactttt acttgctaat ataacaagag aaatttttaa
    17161 aacatataag catacatact tgatttcggg ttctatgttg atagggatga ttacattgat
    17221 aataggtcaa ttttttatac aacatgtatt taagtttgat acaactttaa gtgtagtaat
    17281 aaattttata ggaggaattt actttattca attactatta aagggggcaa atagatgata
    17341 gagataaaaa atatatttaa aagatataag aataaaaatg ttgtagatga tgtctctttt
    17401 agtatagaaa agggaaagat aacatctttt ataggaccaa atggagctgg aaaaagtaca
    17461 gtactatcaa tagttacaag acttatagga ggtgatggtg gagaagtaat aatagaagga
    17521 aaaagcttga ctaattatag caataaagaa ttagcaaaaa aaatagctat tcttaaacaa
    17581 tctaacaata taactttaaa gcttacaata agagaattag ttggatttgg aagatttcca
    17641 tatagtgaag gtaatctaac taaagaggat gaaaattata ttgatgaagc aatagaatat
    17701 atgaagttga ctgatataca acataagtat ttagatgaat tgagtggagg tcaaagacaa
    17761 agagcttata tagcaatggt aatagctcaa gatacagagt acatattact tgatgaacca
    17821 ctgaacaatt tggatatgaa ccattccgta cagatgatga aggtacttag aagtctttgt
    17881 gatgagttag ataagactat agtattagta atgcatgata taaattttgc atcatgttat
    17941 tcagataata tagttgcatt aaaaaatgga aaagttaaaa aagtaggtcg tacagatgag
    18001 atagtaaatg aaaaagtttt agaagatatt tatgagatga attttaacat taagaatata
    18061 aatggaaatc gaatctgtat ttatttttaa aatattgtat atgaaaataa acttgctata
    18121 tgatttttta taaagttttt aaattaaaat aaagattaat aggagagagg aaaatattga
    18181 tatgaataaa aaagcagcaa tagtagcagc agtagctatt ataggattag tgacagtgtt
    18241 tgcattaggt ggaagtaaaa agaatgaatc aaaaacatca gaaaattcaa ataatactat
    18301 gaagataact cataacttgg gagaaacaga tgtaaaatta aatcctaaaa aagtagtggt
    18361 atttgattat tcggctttag atacaatgga tgcattaggt gtagctgaga atttagtagg
    18421 acttccaaaa gcgagtttac cagcatcctt agaaaaatat aaggatgaca agtatgcaga
    18481 tttaggagga ttaaaagaac cagatttaga gggtataaag tcggcaaatc cagatttaat
    18541 tataataaat ggaagacaag aagattttta tgagcaattg tcaaaaatag caccaacaat
    18601 aagtacaagt aaagatgata agaagtactt agaatctgtt aaaaataata tagacaaaat
    18661 agcaaaaata tttggagtag aagaaaaagc aaatcaagaa tttagtaaaa ttgaaaagaa
    18721 aatagaaact ttgaataaaa aagtaacaga taaaaattta aatgctttaa ctataatggt
    18781 aaatgaaggt aatttaagtg tatttggtga agaatcaaga tttagtatat tatacaatag
    18841 ttttggattt gaaaataaag ataaaaatat aaaagaatca agtcatggac aaaatattac
    18901 ttttgaatat atagctaaac aaaatccaga agttatgttc gttatagata gaggaatagc
    18961 tactggcagt gatgtaaaag aaagctcaac tgcaaaatct gttttgaaca atgatataat
    19021 aaaatctatg gatgcatata agaatgataa tataatatat ttagattcac caacatggta
    19081 tgtaaatgat ggtggtctaa catctttaaa taaaatgata gatgatgctt caaaagcggt
    19141 aaattaataa tccgatataa tcaaaatata ttttttataa aatgattatc aaataaacta
    19201 ggagttttta agaactccta gtttattttt tgcataaaaa agatatagtt taaacaataa
    19261 tattatctat aataagataa atctattcaa aatctaataa aatatgaagt tatactagac
    19321 aaaaagaata actcttaaat ataattaagt tatataataa tatataatta taatgatata
    19381 attttaatag gtggtttgta atta
//
LOCUS       DAEPKC010000076        19344 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.076, whole genome shotgun sequence.
ACCESSION   DAEPKC010000076 DAEPKC010000000
VERSION     DAEPKC010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 19344)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19344)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19344
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.076"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            110..739
                     /locus_tag="KR294_002697"
     CDS             110..739
                     /locus_tag="KR294_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240762.1"
                     /translation="MNKYLLINPVAERMYGEKFHLIKANLIKKGYIITECEPQLEYVK
                     KQYKEYTKKTENTMLDCRCPESISLLKRNNLINNFEVPMIEPILVRTCRVLYDKYIKS
                     KDDMLVVTCPCTQLRDFASEKFKDKGNAMFYTWKEFAEQEGVKSLGKIDESPIPLGYF
                     KDTFEKVLEVSSEDEILSEIQKIRNGFEDKYDIVEMFYCKDGCNNGDGL"
     gene            740..1522
                     /locus_tag="KR294_002698"
     CDS             740..1522
                     /locus_tag="KR294_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0240763.1"
                     /translation="MVNKFNNKFLRLVKSVLIFFIILLLWKITNYLGIWSDYILPSPE
                     KVYSTFLNMISDGSIFINVYASMKRVLIGFAISTAIGVPLGIFFGIYSGVYEYFKSLI
                     NFLRNTPPLALIPMLILWFGIGEESKIIIIVLASFFPIFTSTLKGIKNCDSKLIEVGR
                     VFEFSKLQIIFKIIIPNAILDIAVGLKLALGYSFRAIIGAELVAASSGLGYLISDGKE
                     MSRTDVVIVGIIVIGLLGIITDYIFSIIVKKVSKGKMVEAYE"
     gene            1515..2393
                     /locus_tag="KR294_002699"
     CDS             1515..2393
                     /locus_tag="KR294_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0240764.1"
                     /translation="MNNLVCDSGYIIRNLYKSYKVDNKEHVVLSDISLNIDRNHITVI
                     LGESGCGKTTLLRAIASLEGINSGEIRFINDNKEYRPNVGFVFQESRLMPWLNVSENI
                     AFHNQRKNTILNKVLRKFKHNKRIRSKIINDNFRSLETNDNLNKSNKYNRKSNIDVEK
                     YLKMMNLQKFKNSYPNELSGGMAQRVSIARALSFNPDMLLMDEPFSALDYFTRIDMQN
                     EVIRIHKSTNKGVIFVTHDIDEALKIGKKIVVFTDERKVKEFNIEDGYNRDLTSDYYI
                     KLKKDILMTMKSNKGI"
     gene            2426..3385
                     /locus_tag="KR294_002700"
     CDS             2426..3385
                     /locus_tag="KR294_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NrtA/SsuA/CpmA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HBH0240765.1"
                     /translation="MKLKKLLIGITILTLATASLAGCAKKNNGEKLSEINLTYVKSPL
                     NVPSIIQKQDDLFGKEFKKDNIKVNFHEITTGPEQTQALAAGEIDFLHALGGTSALIA
                     ASNGVELKILNTYSRSPKGFMILTNNNSIKSAADLVGKKVAGPKGTILHQVLISALDK
                     EGLSMDDVEFVNMGIPEASAALSDGSVDAALIAGPAALKAMKSGSKLVANGEGLVDGI
                     IVTAVSTDFAEKHPEIVERFMKVEKETLEYVNNNFDEAMEKVAKEVDLSLEETKELYA
                     WYDFSLDITDKDISSLEDTQDFLIKNKLQEKKVNIKELIYNAK"
     gene            3699..4391
                     /locus_tag="KR294_002701"
     CDS             3699..4391
                     /locus_tag="KR294_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011987369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0240766.1"
                     /translation="MSYKVYIVEDDISISTLLKDYIEKYGFEVIVEENFDDIMITFES
                     FKPHLVLLDVNLPKFDGFYWCRCIRQQSNLPIIFISARDGNVDQIRALESGADDYITK
                     PFYYDVVMAKIKSHIRRVYGEYSPKIDERIVELDGLKFYPERLELELNGENLIITKKE
                     GILIECLIKRYPKVVSRDYLLEKIWDDIEFVEENTLNVNVSRIRKRFEELGIDNAVQT
                     VRGLGYKLNKNW"
     gene            4401..5405
                     /locus_tag="KR294_002702"
     CDS             4401..5405
                     /locus_tag="KR294_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH0240767.1"
                     /translation="MKLFLKDYKGYIFIYYIGIVMTIIYCNLMKFISFGESLYILLFS
                     SFILLCFLIYKYYKNREVYNLFEKGVHSLEESFLYLGSSFLGRNISVILKQQHKLYQS
                     MIQEHKKIHSEHLTFINQWIHQMKTPISVISLQLQDYEGEEVTENIRKEIDRLNKGLD
                     MAMHFARADNFQKDFIVEKAKLNEIVSSIVNEEKRLFIKSGMIPKIQVDKFTYVYTDV
                     KWMKFIIGQLITNGVKYSKDYSNYLTIKSEENNKYVILSIIDEGIGIVSKDLKRVFAP
                     FFTGENGRKFGESTGMGLYLVKKVCDDLGHKVSIKSEVGKGTEVSIYFNKGVNSLIKM
                     "
     gene            5653..6504
                     /locus_tag="KR294_002703"
     CDS             5653..6504
                     /locus_tag="KR294_002703"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HBH0240768.1"
                     /translation="MSLDVIFILKSVIIAIVEGLTEFIPVSSTGHMILVGNLIDFKGQ
                     FAEMFEVVIQLGAILAVVVLYWKKIKDSVIEFFKFIFTGGKEGKIGFRFGMNVIIGCI
                     PFAIIGVLFYDNIKSLFNLQSVIIGFIVGGILLLVVETLFRKKNHSTDNIDKITPIQA
                     LKVGTLQVLSAWPGMSRSASTIMGGWIAGLNSPTAAEFSFFLAVPAMVASSGKDLFEF
                     DYSIMTPTLWIALVVGFIVAFIVSIIVMEKFVNFLKKKPMRVFAVYRIIMGVVLAVLA
                     FTNIISV"
     gene            6608..7354
                     /locus_tag="KR294_002704"
     CDS             6608..7354
                     /locus_tag="KR294_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001637630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0240769.1"
                     /translation="MKILTVNNLSKVYGKKIIFNALNDINFSIEDGEFVGIMGPSGSG
                     KTTLLNMISTIDKPTTGTMELKGKNPLLLRGEELALFRRRELGFVFQDFNLLDTLTIG
                     ENIVLPLTLDKVSVKEQDERLNEVSTILGIKDLLGKRTFEVSGGQAQRTAIARALINN
                     PSILLADEPTGNLDSKSSKVVMELFQKINKENKVTTMMVTHDPLAASYCSRILFIKDG
                     SIYNEIYKGSSREQFYQEIMDVLTLLGGDN"
     gene            7354..9270
                     /locus_tag="KR294_002705"
     CDS             7354..9270
                     /locus_tag="KR294_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0240770.1"
                     /translation="MNIKQFAINNISRNIKAYLGYLASIVISSSLLFSFIMFTSHPDL
                     DVSQFPDYLKEGLKMSKIIAYLFLFFFVFYSVSVFLKSRYKEFGILYITGISKRQVMK
                     LIFIENMIINIVSSVIGIIIGLIFAKIFLVVMSTFLELSPLKFYIPFNAILSTLIYFM
                     ILAVLTSIFTSFIVKENQVLKLLKGTKTPKPEPKTSLMLAILSICLFIIAYYNAITST
                     DQYTTYLRLVPVTSLTIVATYLFFSQFSVFFMKKLKLNKRFYRKNTNMLWISNLIYKV
                     KDNARIFFLITITSAVAFTAIGTVYSFWKDVERQINLIYPNTIYYSTMTLHNDPKKPD
                     SKEKDKERMMFIENNLKKENVDYTRINGEFKTVFPKKSDFNVRIMKESKYLEITETIG
                     VKPISFEDNECISLLSSSLPGNKNVKENIIVGNRGLKVAKQVEECVMPAYYKNMYVVK
                     DNFYDSIESKFIVDRFTAFEVEDSSKTIEICREFENKFNNESGMQPYLFFSKELMIGT
                     GKLMYSTFIFLAIFIGLIFFVTTSSFLYNKFYMDCQVDKKKYEQLNKLGMTYNEIKKA
                     STIEIGIVFLFPYVVAVIHSIFALTALKNSFDIEVASSAVLVMGSLFLVQIVYFLIVR
                     NNYLKEIRLNLVNF"
     gene            9549..10466
                     /locus_tag="KR294_002706"
     CDS             9549..10466
                     /locus_tag="KR294_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing protein"
                     /protein_id="HBH0240771.1"
                     /translation="MMILIQSRGKMKCKELSEELEVSERQIKSYKMYLEQAGIFINST
                     PGIYGGYEIDKCNSISLIKLLDSEVSILDMINSQLEYNNDIYKNEFNNIVEKIKAVLN
                     TGEKSDTYMDYFTVQAQRNCDYESEKNKCNEIIRAYTTKHKFWIEYYSLNSGNSERIV
                     HPYGLFNYKSDTYMVAFCEKRFKFIDFKLCRIKDYKVLEEKYNVDKSFSWDEYSKNSI
                     GIYKGEEINVVIKISHPFSTIIKEKVWVNNQQIIEYDDKSIMFKAKMRGYEEIKSWIL
                     SMGAYVEVVEPDRLRNDILLEIEKMKKIY"
     gene            10544..11281
                     /gene="cas6"
                     /locus_tag="KR294_002707"
     CDS             10544..11281
                     /gene="cas6"
                     /locus_tag="KR294_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endoribonuclease Cas6"
                     /protein_id="HBH0240772.1"
                     /translation="MKMKIEFSTGCIPISYNSLFMSIIKEAIRKSNEDYYKNMYYYKE
                     KNNKKTKNFTFSVYIKKYSIEGDNFIIEDKVILNISTPDLELGFHIYNGLMTSKKCLY
                     KDYELTRIRIDLSREKKVTEERVLFNALSPICVKSKEGKFLEITDDRYIEELNYITNE
                     VVKNYRGNGLKRKLEFENIGLKKVVVKESLREFKKITGKEYQYINGYKGKFILKGDID
                     DLNLIYNLGIGFRRAQGFGDVDILEWR"
     gene            11287..13137
                     /gene="cas8a1"
                     /locus_tag="KR294_002708"
     CDS             11287..13137
                     /gene="cas8a1"
                     /locus_tag="KR294_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated protein Cas8b1/Cst1"
                     /protein_id="HBH0240773.1"
                     /translation="MKLRVYRGDWFFNMGIVGFLNIIKKADKQAEIFIMEDYIEFDSL
                     FLENFHEYYFNYFMDEYDVSKRIKKNIDYSINFIKSKPDRIKDGIKKIKDSVKQQNDK
                     IKKFDEEKFNMIKEKLDSMSKIKSYDEFDSLEALVDETIDIFKIKSINDRLTANLYKY
                     VVQDNYFGQVSFFNVAKAKLDLDGLKQVMFNDYLRQIIYFGELEDLLEENDYDKLKNY
                     LNDRLNSIAKDINEKKVSKSSINTIEKIMKEINKNFIKKNKSIEDIKKYMDSLEVCEM
                     CGLYKGILDEYSESNFAPLGVSTNNARNMFWNQAYVPSICDICKLILFCTPAGATYTR
                     KNYLINEENEFYLFVNMDTCINELFERNNSLKAQKSEYSDSKDENPFNQLIKSIVEEN
                     TLKSEWQLRNILFVEFKASIDSKKCKINYFNIPTYLAKFFVKENKKIQSIYDYKLKSN
                     VLDLILKSKDLKHLINNTLRNIVKSNLESNNKSNISGLSCFNVVQLRTILNNYKRGVY
                     KMDYKKLRKIYESGCEIHDYYIDKNAKNKIEGITYKILNLIKVGNKNDFMQTILRIFS
                     PSEKTPPEEILQIFVEEDLDFESVGYAFVTGLISGKYEGKDKLPNEKEEK"
     gene            13139..14053
                     /gene="cas7i"
                     /locus_tag="KR294_002709"
     CDS             13139..14053
                     /gene="cas7i"
                     /locus_tag="KR294_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated protein
                     Cas7/Cst2/DevR"
                     /protein_id="HBH0240774.1"
                     /translation="MKRGLTFTVIAQAQSLNYGEGIGNISELKKLSRDDGNIYTFASR
                     QCLRYDIVRLAAELFNWNLQVVDKEKGTIQFKDNISIRESEEMDLFGYMKTNKKDEKD
                     KKGGSLTREATVRLSNAISLEPYRSDMDFLNNKGLADRIGEHPNLANIEQHLSYYTYT
                     VTIDLSKIGKDGDIELDNKEKCRRVVEFLEIIKVLNRNIRGRQENLSPLFVVGGVYEI
                     ANPFFLGRIKLKGDKNGFKINKQAIEEVIQGTFLGKDLKEFTYVGMVDGVFINKEEFK
                     GLFEDNFLSVDKFFGQLVKEVKEYYGVN"
     gene            14055..14756
                     /gene="cas5b"
                     /locus_tag="KR294_002710"
     CDS             14055..14756
                     /gene="cas5b"
                     /locus_tag="KR294_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated protein Cas5"
                     /protein_id="HBH0240775.1"
                     /translation="MKVLKLDLFQETACYKKPFAMKITETYPLPPYSTINGLIHKILN
                     ATEYIPFNISVQGTYESIFNNYQTTYFYKKDSITSMPMNSHMLLNVNLIIHIGGDFDL
                     LEEIYDSLLNYDEHLSLGRKEDLVRINDIRFVEVNKFEVDEDIQLDDYENYKLSECNI
                     RMPIYIPKTSLQDTDIDGISYRLNNYYDNNAVEDKKRVWNKVDSYYVEDGNTISIGDI
                     LLDNEGDLLYFNNIN"
     gene            14767..17088
                     /locus_tag="KR294_002711"
     CDS             14767..17088
                     /locus_tag="KR294_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated helicase/endonuclease Cas3"
                     /protein_id="HBH0240776.1"
                     /translation="MLYAKSNPVETLREHTDELLKQMNVLRESYGKNINSLDFLEEEI
                     FWQLLDFVIEFHDIGKAFSPFQELIKSRMDTKINEPKIVTYLENNVGHNYLSPAFIDY
                     SYIDRKKNKELRAVLNQVIVYHHERDIFIDKDFKNLIQKILDEDLINKVYELQHEFKV
                     RYPIKTEKLSKVYLQSVEKRIDKNHKYYNLYIMLKGILHRLDHSASAHEVVECNNVIN
                     IGEQTENYLMKEFGSLREAQSFAKSNRNKNIILIASTGMGKTETALIWIDKDKAFFTL
                     PLRVSINALFDRAKNIVGVGESNDTFLGLLHSTAIDYLEESNQENSSEIVDLAKLLSC
                     KLTFSTIDQIFKFPFLYRGYEKVYSTLAYSKVVIDEIQAYSPEIAAVLVKGIEMIHKI
                     GGRFMIMTATMPTIYIDELKKRGVMNSNLAELTCNTEKIRHCVSIVENSIDENLGKII
                     QSGMNKKVLVIVNTVKSAVEKYELIEEIVKPKGIDVNLNLLHSMYIQEDRAKLEKYIK
                     EFANSDRNGIWITTQLVEASLDIDFDELHTENSTLDSLFQRFGRCYRSREYEENSPNI
                     FIYTEKATGIGSIYDKDIVEKGLELLKTFINGKECVKMKEKYKVEMVKILYSKESLEG
                     TAFEKRFTSALNILDTITPYSLGSKDAQNILRNIEGYTVIPEDIYNKIEETLIKDYEE
                     LGQELINAYSNDDRQLINKIKSKRKKARREIIKKTVNLPIYKAKQNVIDIQVKGLEDL
                     KILLYKYDIYENKHTKQIFGKGVLISNEIDQFI"
     gene            17103..17654
                     /gene="cas4"
                     /locus_tag="KR294_002712"
     CDS             17103..17654
                     /gene="cas4"
                     /locus_tag="KR294_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated protein Cas4"
                     /protein_id="HBH0240777.1"
                     /translation="MWLKFTKEGDFVPIDLEVLKVQGVKINYYYVCKRKLWLFSKGIT
                     MEQNSSRVLSGKIVHEDSYKRMKNKEILIDDILKLDIIKDEYVKEVKISSKMKEADEM
                     QLYYYLYYLKNSMGIEKKGTINYVKEKKQEELILTEEKERIIENTLININEINMQLSP
                     PKIEKKHYCTKCAYYEFCFVKEE"
     gene            17657..18637
                     /gene="cas1b"
                     /locus_tag="KR294_002713"
     CDS             17657..18637
                     /gene="cas1b"
                     /locus_tag="KR294_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated endonuclease Cas1"
                     /protein_id="HBH0240778.1"
                     /translation="MYKDYYIISNGDIKRKENTIYYYNLEGEKKILPVEQVDDIHIYG
                     EVDLNTKLINYISKYGVMLHFYNYYGYYSGTYYPRKKNVSGFSLVCQSACYLDKNERL
                     YLAKSFVESASYHILRNMRYYKVDESLIDTIKDELNDLNDVKEISELMGKEGRIRKTY
                     YKSFNQILKDDFEFYKREKRPPKDPVNALMSFGNSIMYTNVLSEIYKTQLDPTISFLH
                     EPSTKRFSLSLDIAEIFKPIIIDTIIFSLINNKRINKNDFEYQDKICYLSEKGKKKFL
                     QEFENKMQTTIKHRNLNRKVSYRMFIRLECYKLIKHFINDERYKVLKVWW"
     gene            18640..18906
                     /gene="cas2"
                     /locus_tag="KR294_002714"
     CDS             18640..18906
                     /gene="cas2"
                     /locus_tag="KR294_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endonuclease Cas2"
                     /protein_id="HBH0240779.1"
                     /translation="MFVIVTYDIVEARSLNRIRRILRKYLTWTQNSVFEGNITEGKLH
                     KCISEIENIIDNSEDSIYVYEIKNPNSIKKKCYGIDKYSDEMFI"
BASE COUNT         7915 a         1681 c         3375 g         6373 t
ORIGIN      
        1 tagataaaaa ttgttttatt aagaaaaaat taatatattg acaaaattta agtgctcatt
       61 taaactatta attgataata atattcaata ttaaataata ggaggcgtta tgaataaata
      121 tcttctaata aatccagtgg cagaaagaat gtatggagaa aagtttcacc ttattaaagc
      181 aaatttgata aaaaaggggt acataataac agaatgtgaa ccacagttag aatatgtaaa
      241 aaagcagtac aaagagtata caaaaaagac tgaaaataca atgttggatt gtagatgtcc
      301 agaaagtata agtcttttaa aaagaaataa tttgataaat aattttgaag tacctatgat
      361 agaaccaata ttagtaagga cttgtagggt tttatacgat aaatatataa aaagtaaaga
      421 tgatatgttg gtagtaacct gtccatgtac acaattaaga gactttgcaa gtgaaaagtt
      481 taaggataag ggtaatgcta tgttttatac atggaaagag tttgctgaac aagaaggtgt
      541 aaaatcactt ggaaaaatag atgaatcacc aattccatta ggatatttca aagatacttt
      601 tgaaaaagtt cttgaagtat caagtgaaga cgaaatatta agtgaaatac aaaaaataag
      661 aaatggtttt gaagataagt atgacatagt agaaatgttt tattgtaaag atggttgtaa
      721 taatggagat ggtttgtaaa tggtcaataa atttaataat aagtttttaa ggctagtaaa
      781 gagtgttctg atatttttta taattctttt attatggaaa attacaaatt atcttggtat
      841 ttggagtgat tatatattac catcacctga aaaggtatat agtacatttt taaatatgat
      901 aagtgatggt tcaatattta ttaatgtata tgcaagtatg aaaagagttt tgataggttt
      961 tgcaataagt actgctatag gtgtgccttt agggatattc tttggaattt atagtggagt
     1021 atacgaatac tttaaatctc taataaattt tttaaggaat acacctcccc ttgctttaat
     1081 accaatgctt atattatggt ttggtatagg agaggaatca aaaattataa ttatagtttt
     1141 agcatctttt ttcccaatct ttacaagcac attgaaaggg attaaaaatt gtgactcaaa
     1201 actgattgaa gtgggtagag tatttgagtt ttcaaagctt cagataatat ttaaaataat
     1261 aataccaaat gccattcttg atattgctgt tgggttaaag ttagctcttg gatatagctt
     1321 tagagcaatt attggggcag aacttgtagc agcttcatct ggtcttggat acttgatatc
     1381 tgatggaaaa gaaatgtcta gaacagatgt tgttattgta gggataatcg taattggact
     1441 tttaggaata attacagatt acatattttc gattattgtg aagaaggtaa gtaagggaaa
     1501 gatggtggaa gcatatgaat aatttagtat gtgactctgg atatataatt agaaatttat
     1561 ataaaagtta taaagttgac aataaagaac atgtagttct tagtgatatc tctttaaaca
     1621 tagatagaaa ccatataaca gtaattttag gtgaaagtgg ttgtggaaag actaccttgc
     1681 ttagagcaat tgcatcactt gaaggtataa atagtggtga aattaggttt attaatgata
     1741 ataaagagta tagacctaat gttggttttg tttttcagga gagtagatta atgccttggt
     1801 taaacgtaag tgaaaatata gcttttcata atcaaagaaa aaatactatt ttaaacaagg
     1861 tgcttagaaa atttaaacac aataaaagaa ttaggagtaa aattataaat gataatttta
     1921 gaagcttaga aacaaatgat aatttgaaca aatcaaataa atataatagg aaaagtaata
     1981 ttgatgtaga aaaatatctt aagatgatga acttgcagaa atttaaaaac tcttatccaa
     2041 atgaattgtc aggaggtatg gcgcagagag taagcatagc tagagctctt tctttcaatc
     2101 cagatatgtt gcttatggac gagccttttt cggcattaga ttattttaca aggattgata
     2161 tgcaaaatga agttataaga atacataagt caactaataa aggcgtgata tttgtaactc
     2221 atgatattga tgaagcgtta aagataggca agaaaatagt tgttttcaca gacgaaagaa
     2281 aagtaaaaga atttaatata gaagatggtt ataatagaga tttaacttca gattactata
     2341 ttaaattaaa aaaagatatt ttaatgacaa tgaagtcaaa taaaggcatt taaagaaatt
     2401 aataatattt taaggagtaa agtaaatgaa attaaaaaag ctattgatag gtataacgat
     2461 attaacactt gcaacagcat ctttagctgg atgtgctaaa aaaaataatg gagaaaaact
     2521 ttcagaaata aatttaactt atgtaaaatc accattaaat gttccttcta taattcagaa
     2581 acaggatgat ttatttggaa aggaatttaa aaaggataat ataaaagtta acttccacga
     2641 aattactaca ggtccagagc aaacacaagc tttagctgct ggagaaatag acttcttaca
     2701 tgcactaggt ggtacatcag ctttaatagc tgcatctaat ggagtagagt taaagatatt
     2761 aaacacttat agcaggtcac caaaaggatt tatgattttg actaataata attcaataaa
     2821 atcagcagca gatttagtag gtaagaaggt ggcaggccca aaagggacta tattacatca
     2881 ggtattgatt tcagcacttg ataaagaagg attaagtatg gatgatgtgg aatttgttaa
     2941 tatgggtatt ccagaggcat cagcagctct ttctgatggc agcgtagatg ctgcattgat
     3001 tgctgggcca gcagctctta aagctatgaa gtcaggtagt aaacttgtag caaatggtga
     3061 aggtttagta gatggtataa tagtaactgc tgttagcaca gactttgcag agaaacatcc
     3121 agaaatagtt gaaagattta tgaaggttga aaaggaaact ttagaatatg taaataataa
     3181 ttttgatgaa gctatggaaa aagtagctaa agaagttgat ttaagtcttg aagaaactaa
     3241 agaattatat gcttggtatg attttagttt agatataaca gataaagaca tatcttcgct
     3301 tgaagataca caagacttct taataaaaaa taagttacaa gagaaaaaag tgaacataaa
     3361 agaattaatc tataatgcta agtagaaact atgataaaat aatactaagt aagaaatata
     3421 ataaaagttt aagttacctt attaaggtaa ctttttctat tttgaattag taatttcaat
     3481 ttattttaga atgattagtt gataataatg attaattaat cataaaaaga tactttttta
     3541 tagagtttta ttaagatgtc taataatatg gttatactta tgaagtcagt aattgtgaag
     3601 ttagtaatat gattaaattt atatattgta aaaagattat aatatattaa aattggactg
     3661 ttatatgatg agtaaatagg tatattagga ggaattatat gagttataaa gtatatattg
     3721 tggaagatga catatcaata agtacattac ttaaagatta tattgagaaa tatggatttg
     3781 aagtgattgt tgaagagaac tttgatgata taatgattac atttgaaagt tttaagccac
     3841 acttagttct attagatgta aatttaccta aatttgatgg tttctactgg tgtagatgta
     3901 ttaggcaaca gtcgaattta cctataattt ttatatcagc tagagatggt aatgtagacc
     3961 aaattagagc tttagaaagt ggagcagatg attatataac aaaacctttt tactatgatg
     4021 tagtaatggc aaaaataaag agtcatataa gaagggtata tggtgaatat tcacctaaaa
     4081 tagacgaaag aatagtggag ctagatggat taaaatttta tccagaaagg ttagaactag
     4141 aattaaatgg tgagaatcta attataacta aaaaagaagg tatactgatt gaatgtctta
     4201 tcaagagata cccaaaagta gtaagtagag attatctttt agaaaagata tgggatgata
     4261 ttgagtttgt agaggaaaat actttaaatg taaatgttag caggataagg aaaagatttg
     4321 aggaattagg tatagataat gctgttcaga ctgtccgagg gttaggatat aaattaaata
     4381 agaattggta aggagaaagt atgaagttat ttttaaaaga ttataaaggt tatattttta
     4441 tatattatat aggcatagtt atgacaatta tttactgtaa tcttatgaag tttattagtt
     4501 ttggagagag tttatatatt cttttattta gttcttttat attgttatgt tttttaatat
     4561 ataagtatta taaaaataga gaagtatata atctgtttga aaaaggagta cattctttgg
     4621 aggagtcatt tttgtattta ggaagctcat tcttggggag aaatatatca gttattttaa
     4681 aacaacaaca taaattgtat caatcaatga tacaagagca taaaaagata catagtgaac
     4741 atttaacttt catcaaccaa tggattcatc agatgaaaac accaatatca gttataagcc
     4801 ttcagctcca agattatgag ggagaagaag taactgaaaa tataagaaaa gaaatagata
     4861 gattgaataa agggttagat atggctatgc attttgcaag ggcagataat tttcagaaag
     4921 actttatagt tgaaaaagcc aaattaaatg aaattgtatc tagtattgta aatgaagaaa
     4981 aaaggttatt tataaaaagt ggaatgattc ctaagattca agtagacaag tttacttatg
     5041 tttatacaga tgtaaaatgg atgaaattta taataggtca attaattaca aatggagtga
     5101 aatattctaa agattatagt aactacctaa ctataaaatc tgaagaaaat aataaatatg
     5161 taattttaag tataatagat gaaggaattg gaattgtttc taaagattta aaaagggtat
     5221 ttgccccatt ttttacagga gaaaatggtc gtaagtttgg agaatctaca ggtatgggtc
     5281 tttatctagt aaaaaaggta tgtgatgatt taggtcataa agtaagtata aaatcagaag
     5341 taggaaaagg tacagaagtt tcaatctact ttaataaagg tgtaaatagt ttgataaaga
     5401 tgtaaattat ctgttacaat agggttttta gttaattgta cttttttatt atacaattta
     5461 ttaaatgaaa tattcatagt taaataatca aaatttaaga gagtttattt gcaaacctta
     5521 catagatgta aggtttgtgt aatgtttgca gatagttaaa ttttctaatc taaattacaa
     5581 ttaatataag aaataacata agagaaataa cataaaaaaa gaaattttgt aaaaaaggaa
     5641 ggatgtttat tgatgagttt agatgttatt tttatattga aatcagtcat aatagctata
     5701 gtagaggggc ttacagaatt tattccagtt tcatctacag gtcatatgat tttggttggt
     5761 aatttaatag attttaaggg gcaatttgct gaaatgtttg aggttgtaat acaacttggg
     5821 gctatattag cagtagtagt actttattgg aaaaagataa aagatagcgt tatagaattt
     5881 tttaaattta tatttactgg tggaaaagaa ggaaagattg gttttagatt tggaatgaat
     5941 gtaattatag gttgtatacc atttgcgatt ataggagttc tattttacga taatataaaa
     6001 tcattgttta atttacaatc tgtaattata ggatttatag tgggtgggat tttattatta
     6061 gtagtagaaa ctttgtttag aaaaaagaat cattccacag ataatataga taaaattact
     6121 ccaatacaag ctttaaaggt tgggacatta caagttttgt ctgcatggcc aggtatgtca
     6181 aggagtgcat ctactattat gggtggatgg atagcaggac ttaattctcc tacagcagct
     6241 gagttttctt tctttttagc agtaccagct atggtggctt cttcaggaaa agatttattt
     6301 gaatttgatt attcaataat gacaccaaca ttgtggattg ctttggtagt tgggtttata
     6361 gtagctttta ttgtatcaat aatagttatg gaaaaattcg tgaatttttt aaagaaaaaa
     6421 ccaatgagag tgtttgctgt atacagaata atcatgggtg tagtacttgc agtattagct
     6481 tttactaaca taattagtgt atagaaaaaa tagatttatt atctataaaa attaaactaa
     6541 gataaattat aattaacaat tatatatatg ttatttcaaa aattaaatta ggaaggatag
     6601 ttaaataatg aaaattttaa ctgtaaataa tttaagtaaa gtatatggta aaaaaataat
     6661 tttcaacgca ttaaatgaca taaattttag tatagaagat ggagaatttg taggaattat
     6721 gggtccatct ggtagtggaa aaactactct tttaaatatg atttctacta ttgacaagcc
     6781 aactacagga actatggaat taaagggcaa gaatccttta ttgttaagag gtgaggaact
     6841 tgcattattt agaagaagag agttaggttt tgtatttcag gattttaatt tattggatac
     6901 attaactata ggagaaaata tagtattgcc attgacatta gataaggtca gtgtaaaaga
     6961 gcaagatgag agattgaatg aagtatctac aatattaggt ataaaagatt tattaggaaa
     7021 aagaactttt gaagtatcag gtggtcaagc tcagaggact gctattgcta gagcattgat
     7081 taacaatcca tcaatacttt tagcagatga accaacaggt aatttagatt caaagtcatc
     7141 aaaggttgta atggagctat ttcaaaagat aaataaagaa aataaagtta ctactatgat
     7201 ggtaactcat gacccattag cagcgagcta ctgtagtaga atcttattca taaaagatgg
     7261 gtctatatat aatgaaatat ataagggtag tagtagagag cagttttatc aagagataat
     7321 ggatgtactt acattattgg gaggcgataa ctaatgaata taaaacagtt tgctattaac
     7381 aatatttcaa gaaatattaa agcgtattta ggatacttag caagtattgt tatatcatct
     7441 tcactgctat tttcttttat tatgtttaca agtcatccag atttagatgt atctcaattt
     7501 cctgattatt taaaagaagg tctcaagatg agtaagataa ttgcatatct attcttattc
     7561 ttctttgtgt tttattcagt tagtgtgttt cttaaaagta gatataaaga atttggaata
     7621 ctttatatta caggtatatc aaagcgccaa gtaatgaaat taatctttat agaaaatatg
     7681 ataataaata tagtatcttc tgtaattgga ataataatag gcttaatctt tgcaaagata
     7741 tttttagtgg ttatgtctac ttttttagaa ttatcaccat taaaattcta tataccattt
     7801 aatgcgatat tgtctacttt aatctatttt atgattttag ctgtattaac atcaatattt
     7861 acttctttta tagttaaaga aaatcaggtg ttgaagttac ttaaaggtac aaaaactcca
     7921 aaaccagagc ctaaaacatc actaatgctt gctatattaa gtatttgttt gtttataata
     7981 gcgtattata atgctattac ctcaaccgac caatatacaa catatctgcg cttagttcca
     8041 gttacatccc ttactatagt agcaacttac ttgttctttt ctcaatttag tgtatttttt
     8101 atgaagaagc taaaattaaa caagagattt tatagaaaaa atacaaatat gctttggatt
     8161 tcgaacttga tttataaggt aaaggataat gctagaatat ttttcttgat aactataact
     8221 tctgcagtgg catttactgc tataggtaca gtttattcct tttggaaaga tgtagagcgt
     8281 caaattaatt taatatatcc taacacaata tattattcaa caatgacatt gcataatgac
     8341 cctaaaaagc ctgatagcaa agaaaaagac aaggaaagaa tgatgtttat agaaaataat
     8401 ctaaaaaaag agaatgtaga ctatacaagg attaatggtg aatttaaaac tgtatttccc
     8461 aagaaaagtg attttaatgt cagaattatg aaagaatcta agtacttaga aattacagaa
     8521 actatagggg ttaagcctat aagttttgaa gataatgaat gtatatcatt attatcatca
     8581 agtttaccag gaaataagaa cgtcaaagaa aatattattg tagggaatag aggtttaaag
     8641 gtggcaaaac aagtggaaga atgtgttatg ccagcgtatt acaaaaatat gtatgtggta
     8701 aaggataatt tttatgatag tatagaatca aaatttatag tggatagatt tactgcattt
     8761 gaagtagagg attcaagtaa aactatagag atatgcagag aatttgaaaa taaatttaat
     8821 aatgagtcag ggatgcaacc atatttgttt ttctctaaag aattaatgat aggaactggg
     8881 aaattaatgt attctacatt tatattttta gcaatattta taggtttaat tttctttgtt
     8941 actacaagta gttttttata taataaattt tatatggatt gccaagttga taagaaaaag
     9001 tatgaacagt taaataaatt gggtatgaca tataatgaga ttaaaaaagc ttcaacaatt
     9061 gagattggaa tagtattttt gtttccttat gtagtggctg ttatacattc aatatttgca
     9121 cttactgcac tgaaaaattc ttttgatata gaagtagcat catcagctgt tttggtaatg
     9181 ggaagcttgt tcttggttca aatagtttat tttttaattg taagaaataa ttatttaaaa
     9241 gagataaggt taaatttagt caatttttag ttactattat taaatgataa taaaaagggt
     9301 ttagaattaa ttaatattac tggaattata gatgtttatt ttttcagtaa tattttttat
     9361 tgtattaact attaaaattt tgtacaaata taaaatataa tatggtaaat gtcaaaatta
     9421 taaaaaaatt ctacttatat aaaatataaa gaggttatat gtacatatgt gtagaaataa
     9481 ataataaaaa tatcaattaa tgttattagg gggggttact cattagtaaa ttagctaata
     9541 cacttagaat gatgatatta attcaaagca gaggcaaaat gaaatgcaaa gaattatcag
     9601 aagagttgga agtaagtgaa aggcaaataa aaagttacaa gatgtattta gagcaagctg
     9661 gtatatttat aaattcaaca cctgggattt atggtggtta tgaaatagat aaatgtaata
     9721 gcatctcatt aattaaatta ttagatagtg aagtttcaat tctagatatg ataaattcac
     9781 agttagagta taataatgat atttacaaaa atgaatttaa taatattgta gaaaaaataa
     9841 aagcagtatt aaatacagga gaaaaaagcg atacatatat ggattatttt acagttcaag
     9901 cacaacgtaa ttgtgattat gagtctgaaa aaaataagtg taatgaaata attagagcat
     9961 ataccacaaa acacaaattt tggatagaat attattcatt aaattcagga aatagtgaaa
    10021 gaattgttca tccatatggt ttatttaatt ataaatcaga tacttatatg gtagcttttt
    10081 gtgaaaaaag atttaagttt atagacttta aattatgtag gattaaagat tataaggttt
    10141 tagaagaaaa atataatgta gataaaagtt ttagttggga tgaatatagt aaaaatagta
    10201 taggaattta taagggagaa gaaattaatg ttgttataaa aattagtcat ccattttcaa
    10261 caattataaa ggagaaagtt tgggttaata atcaacaaat catagaatat gatgataaat
    10321 ctataatgtt taaagctaaa atgagaggtt atgaggagat aaaaagttgg attttaagta
    10381 tgggagctta tgttgaggtt gtagaaccag atagacttag aaatgatata ttgttagaga
    10441 ttgaaaaaat gaaaaaaatt tactgatttt ttcaaataat ttatacttgg accaatatac
    10501 ttcacggtct agtgttaata tattaattga gagaggtgat attatgaaaa tgaaaattga
    10561 atttagtaca ggttgtatac caatatctta taattcgctc tttatgagta ttataaaaga
    10621 agcaataaga aaatctaatg aagattacta taaaaacatg tactattata aagaaaagaa
    10681 taataaaaaa actaaaaatt ttacattttc ggtttatata aaaaagtata gtattgaagg
    10741 tgacaatttt attatagaag ataaagtaat attaaatata agtactccag atttagaatt
    10801 gggttttcat atatacaatg ggttaatgac ttctaaaaaa tgtttatata aagactacga
    10861 acttacaaga attagaatcg atttatcaag agaaaagaag gtaacagaag aaagggtact
    10921 atttaatgca ttgtctccaa tctgtgtaaa gtctaaagaa ggaaaattct tggagataac
    10981 tgatgataga tacatagaag aactaaacta tataactaat gaagtggtta aaaattatag
    11041 ggggaatgga ttaaaaagaa agttagaatt tgaaaatata ggtctcaaaa aggtagtagt
    11101 taaagagagt ttaagagaat ttaaaaaaat aacaggtaaa gagtatcaat atattaatgg
    11161 ttacaaaggt aaatttatat tgaaaggtga tattgatgat ttaaatctta tctacaatct
    11221 aggaattggt tttagacgtg ctcagggatt tggagatgta gatattttag aatggaggtg
    11281 agataaatga agttaagagt ttatagagga gattggtttt ttaatatggg tatagttgga
    11341 tttttaaata taataaagaa agcagataaa caagctgaaa tatttattat ggaagattat
    11401 atcgaatttg atagcttatt tcttgaaaac tttcatgagt attattttaa ttactttatg
    11461 gatgaatatg atgtatcaaa aagaattaaa aaaaatattg attacagtat aaattttatt
    11521 aaatctaagc ctgatagaat caaagatgga attaagaaaa ttaaagatag tgtgaaacaa
    11581 caaaatgata agattaaaaa atttgatgaa gaaaaattta acatgataaa agagaagcta
    11641 gatagtatgt ctaagataaa aagttatgat gaatttgata gtttagaagc tttagtagat
    11701 gagactatag atatatttaa aataaaatca ataaatgaca ggcttacagc aaatctttat
    11761 aaatatgtag ttcaagataa ttattttgga caagttagtt tttttaatgt tgctaaggcg
    11821 aaattagatt tagatggatt aaaacaggta atgtttaatg attatttaag acaaattata
    11881 tattttggag agttagaaga tttattagaa gagaatgact atgacaagtt gaaaaactat
    11941 ttaaatgata gattaaatag tatagctaag gatataaatg aaaaaaaagt tagtaagtct
    12001 agtataaata ctatagaaaa aattatgaag gaaataaata aaaactttat aaagaaaaat
    12061 aaaagcatag aagatataaa aaagtatatg gatagtttag aagtatgtga aatgtgtggt
    12121 ttatataagg gaatattaga tgaatactca gaaagtaatt ttgctccact tggagtaagc
    12181 accaataatg ctaggaatat gttttggaat caggcgtatg taccatcaat atgtgatatt
    12241 tgtaagctaa tattgttctg tactccagca ggggctactt atacaagaaa gaattattta
    12301 attaatgaag aaaatgagtt ttatttattt gttaacatgg atacttgtat aaatgagctt
    12361 tttgaaagaa ataatagttt aaaagctcaa aaaagtgagt attcagattc caaagatgaa
    12421 aatcctttta atcagcttat aaaaagtata gtagaagaaa atacattaaa aagtgaatgg
    12481 caacttcgta atatactttt tgtggaattt aaagcaagta tagattctaa aaaatgtaaa
    12541 ataaattatt ttaatattcc aacttattta gcaaagtttt ttgtaaaaga aaataaaaaa
    12601 atacaaagta tatatgatta taaacttaaa tcaaatgtgt tagatttaat tttaaaaagt
    12661 aaagacttaa aacatttaat taataacact ttaaggaata tagttaagag taatttagaa
    12721 agcaataata aatcaaacat atcagggtta tcttgtttca atgttgttca attaagaaca
    12781 atattaaata actataagag aggagtgtat aaaatggact ataaaaagtt gagaaagatt
    12841 tatgagtcag gttgtgaaat acatgattat tatattgata agaatgctaa aaataaaata
    12901 gaaggaataa catataaaat tttaaattta attaaggttg gtaataaaaa tgattttatg
    12961 caaacaattt taagaatttt ttcaccaagt gaaaaaacac caccagaaga aattttacag
    13021 atatttgttg aagaagattt agattttgaa tctgtagggt atgcatttgt aacaggatta
    13081 atttctggaa aatatgaagg aaaagataaa ctaccaaacg aaaaggagga aaaataagat
    13141 gaaaagaggg ttaacattta cagtaatagc acaggctcaa agtttaaact atggggaagg
    13201 gataggtaat atatcagaat taaaaaaatt aagtagagat gatggaaata tatatacatt
    13261 tgcatctcgc cagtgtttaa gatatgacat agtacgatta gcagcagaat tgtttaattg
    13321 gaatttacag gttgtcgata aagaaaaagg cactattcaa tttaaagaca atataagtat
    13381 aagagaatca gaagaaatgg atttatttgg atatatgaaa acaaataaaa aagatgagaa
    13441 agataaaaaa ggaggttctt tgactagaga agctactgta agattaagta atgcaatttc
    13501 ccttgagcca tatagaagtg acatggactt tttaaataat aaaggattag cagatagaat
    13561 aggagaacat cctaatcttg ctaacataga gcaacattta agttattata catatacagt
    13621 gactatagat ttatctaaaa taggtaagga tggagatata gaacttgata ataaagagaa
    13681 atgtagaaga gtagtagaat ttttagaaat aataaaagta ttgaatagaa atattagagg
    13741 tagacaagaa aatttatctc ctctatttgt agtaggagga gtatatgaaa tagcaaatcc
    13801 atttttcttg ggtagaatta aattaaaagg agataaaaat ggatttaaaa taaataagca
    13861 agctatagaa gaagtaattc aaggtacttt tttaggaaaa gatttaaaag aatttaccta
    13921 tgttggaatg gtagatgggg tatttataaa taaagaagaa tttaagggat tgtttgaaga
    13981 taatttttta agtgtagata aattttttgg acaactagtt aaagaagtaa aggaatatta
    14041 tggggtgaat taatatgaag gttttgaaat tagatttatt tcaagaaact gcatgctaca
    14101 aaaaaccatt tgctatgaag attacagaga catatccact gcctccatat tctacaataa
    14161 atggattaat tcacaaaata ttaaatgcta cagaatatat accatttaat ataagtgtac
    14221 agggaacata tgaaagtata tttaataatt accagacaac atatttttat aaaaaagata
    14281 gtattacatc tatgccaatg aatagtcata tgctattgaa tgtaaatttg ataattcata
    14341 taggtgggga ttttgattta ttggaagaaa tatatgatag tttattaaat tatgacgagc
    14401 acttatcatt aggtagaaaa gaagatttag taagaattaa tgatattaga tttgtagaag
    14461 tcaataaatt tgaagtagat gaggatatac aattagatga ttatgaaaat tataagttat
    14521 cagaatgtaa tataagaatg cctatatata taccaaaaac aagtttacaa gatacagata
    14581 tagatggtat aagttacaga ctcaataatt actatgataa taatgctgtg gaagataaaa
    14641 aaagggtttg gaataaggta gatagttatt atgttgagga tggaaatact atatcaattg
    14701 gagatatatt attagataat gaaggagatt tattatattt taataatata aattaggagg
    14761 gagattatgt tatatgctaa atctaatcca gtggaaacac ttagagaaca tactgatgaa
    14821 cttttaaaac aaatgaatgt attaagagaa agttatggaa aaaatataaa tagcttagat
    14881 tttctagaag aggagatatt ttggcaatta cttgactttg ttatagaatt tcatgatatt
    14941 ggaaaagcat tttcaccgtt tcaagagtta ataaaaagca gaatggatac taaaataaat
    15001 gaacctaaaa tagtaactta tttagaaaat aatgtaggcc ataattatct ttctcctgca
    15061 tttattgatt atagttatat agacaggaaa aaaaataaag aacttagagc agtattaaat
    15121 caagttattg tatatcatca tgaaagagat atctttatag ataaagattt taaaaattta
    15181 atacaaaaaa tattagatga agatttaata aataaagttt atgaactaca gcatgaattt
    15241 aaagttagat atccaataaa aacagaaaaa ttgagtaaag tatatctaca aagtgtagaa
    15301 aaaagaatag ataaaaatca caagtactat aatttatata ttatgttaaa aggaatacta
    15361 catagactag accatagtgc ttctgctcat gaagttgtgg aatgcaataa tgttataaat
    15421 ataggagaac agacagaaaa ttatttaatg aaagagtttg gtagtttgag agaggctcaa
    15481 tcatttgcta aatctaatag aaataagaat ataatactga ttgcatctac aggaatggga
    15541 aaaacagaaa ctgccttaat ttggatagat aaagacaagg cattttttac acttccatta
    15601 agagtaagta taaatgcatt atttgataga gcaaaaaata tagttggtgt tggagaatca
    15661 aatgatacat tcttaggttt gttacattca acagcaatag attatctaga agaaagtaat
    15721 caagaaaatt caagtgagat tgtagattta gcaaagttat tatcttgcaa actgacattt
    15781 tctacaatag accaaatatt taaatttcct tttttgtata gagggtatga aaaagtgtac
    15841 tcaacattag catattcaaa agtagtaata gatgagatac aagcatattc accagaaata
    15901 gcagctgtat tggtaaaagg tatagaaatg atacataaga taggtggcag atttatgata
    15961 atgacagcta ctatgccaac catatatata gatgaattaa aaaaaagagg tgtaatgaat
    16021 agtaacttag ctgaattgac atgtaataca gaaaaaataa gacattgtgt ttctattgta
    16081 gaaaattcaa tagatgaaaa cttaggtaaa ataatacaaa gtggaatgaa taaaaaagtt
    16141 cttgtaatag taaatacagt taaaagtgct gtagaaaaat atgagttaat agaagaaata
    16201 gttaaaccaa aaggaataga tgtcaactta aatcttttac attctatgta tatacaagaa
    16261 gatagagcaa aattagaaaa atatataaaa gaatttgcca atagtgatag aaatggaatt
    16321 tggattacaa cacaattagt agaggcatct cttgatattg attttgatga gcttcataca
    16381 gaaaattcaa cacttgacag tctatttcaa cgatttggta gatgttatag aagtcgtgag
    16441 tatgaagaaa atagcccaaa tatatttata tatacagaaa aagctacagg aataggtagt
    16501 atttatgata aggatattgt agaaaaagga cttgagctac tgaaaacttt tataaatgga
    16561 aaagaatgtg tgaagatgaa agaaaaatat aaggtagaaa tggttaagat actatactct
    16621 aaagaaagtc tagaaggtac agcttttgaa aagagattta ccagtgcttt aaatatttta
    16681 gatactataa cgccatatag tttaggttct aaagatgcac aaaatatact tagaaatatt
    16741 gaaggatata cagtaattcc agaggatata tataataaaa ttgaagaaac tttaatcaaa
    16801 gattatgaag agttgggaca agagcttata aatgcatata gtaatgatga tagacaattg
    16861 ataaataaaa taaagtctaa gagaaaaaaa gcaagaagag agataattaa aaaaactgta
    16921 aatttaccaa tatataaagc taaacaaaat gtaattgaca tacaggtgaa aggtcttgaa
    16981 gatttaaaaa tacttttata taaatatgat atatacgaaa ataagcatac aaaacagata
    17041 tttggtaaag gtgtgcttat aagtaatgaa atagaccaat ttatttgatt tttatattaa
    17101 caatgtggct aaaatttact aaagaaggtg attttgtgcc aatagattta gaagtattaa
    17161 aagttcaagg tgtaaaaata aattattatt atgtatgtaa aagaaaacta tggctatttt
    17221 ctaaaggaat aaccatggaa caaaatagta gtagagtatt gtctgggaag atagtacatg
    17281 aagattcata taaaagaatg aaaaataaag aaatattgat tgatgatatc ttgaagctag
    17341 atataataaa ggatgagtat gtaaaagaag taaaaataag ttcaaagatg aaagaagcag
    17401 atgaaatgca gttatactat tacttatact atttaaagaa tagtatgggt atagagaaaa
    17461 aaggtactat aaattatgtt aaggaaaaga aacaagaaga attgatattg acagaagaaa
    17521 aagaaagaat tattgaaaac acacttataa atataaatga aataaatatg cagttatctc
    17581 ctcccaaaat tgagaaaaaa cattattgta caaaatgtgc ttattatgaa ttttgttttg
    17641 tgaaggagga gtaacaatgt ataaagacta ttatattata agtaatgggg atataaaaag
    17701 gaaagaaaat acgatttact attacaattt agaaggtgag aaaaaaatat taccagtaga
    17761 acaagttgat gatattcata tatatggaga agtagattta aatacaaaac ttataaatta
    17821 cataagcaaa tatggggtga tgcttcattt ctacaattac tatggatatt attcaggtac
    17881 atattatcca aggaagaaaa atgtatcagg attcagttta gtatgtcaat cagcctgcta
    17941 tttagataaa aatgaaagat tatacttagc aaaatccttt gtggaaagtg catcatacca
    18001 tattttaaga aatatgagat attacaaagt tgatgaaagt ttaattgata ctataaagga
    18061 tgaactaaat gatttgaatg atgtcaaaga aatatcagaa cttatgggta aagaaggcag
    18121 aataagaaaa acatactata aatcatttaa tcaaatatta aaagatgatt ttgaatttta
    18181 taaaagagaa aaaagacctc ccaaagaccc agtaaatgct cttatgtctt ttggaaatag
    18241 cataatgtat acgaatgttt taagtgagat atataagaca caacttgacc ctacaataag
    18301 ctttttacat gaaccatcaa caaagagatt ttctttaagt ttagatattg cagaaatttt
    18361 taagccaatt ataattgaca caataatttt tagcctgatt aataataaaa gaattaataa
    18421 gaatgatttt gaatatcaag acaaaatttg ttatttaagt gaaaaaggaa agaagaaatt
    18481 tttgcaagaa tttgaaaata agatgcagac aactataaaa catagaaatc taaatagaaa
    18541 agtttcatat agaatgttta taaggttaga gtgttataaa ttaattaaac attttataaa
    18601 tgatgaaagg tacaaagttt taaaggtgtg gtggtaagta tgtttgttat tgttacttat
    18661 gatattgttg aagcaaggtc gttaaataga attagaagga tacttagaaa atatttgact
    18721 tggacgcaaa attctgtttt tgaaggcaat attactgaag gaaagttaca taaatgtatt
    18781 tctgaaatag aaaatattat tgataatagc gaggattcaa tctatgttta tgagataaaa
    18841 aatcctaatt caattaaaaa gaaatgttat gggattgata agtattctga tgaaatgttt
    18901 atataggttt gcagtgagcg atatttatgc taaaataggt gttaacagtt ggaatataag
    18961 ggattgaagg tgtatgataa ttgttatcaa ttgcactact gctcgctcac tgcaaatttt
    19021 gatgttttta ttgaattata attgcttgat tgaagtgttt tcaatgtatt caaatatacc
    19081 tattttgggg ttttatatta actaagtggt atgtaaataa ttttttcgga tatttaataa
    19141 tttattttaa atttagtttt atattaacta agtggtatgt aaatctcaac agtatctaca
    19201 agaacttcta tatcttctaa gttttatatt aactaagtgg tatgtaaatt aatttagggt
    19261 aacttttata ttattttctt ctatcgtttt atattaacta agtggtatgt aaatttggtt
    19321 gatatagata ttagtcctat tatt
//
LOCUS       DAEPKC010000077        19108 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.077, whole genome shotgun sequence.
ACCESSION   DAEPKC010000077 DAEPKC010000000
VERSION     DAEPKC010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 19108)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19108)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19108
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.077"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..6896
                     /gene="tcdB"
                     /locus_tag="KR294_002715"
                     /gene_synonym="toxB"
     CDS             <1..6896
                     /gene="tcdB"
                     /locus_tag="KR294_002715"
                     /gene_synonym="toxB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_074049122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="glycosylating toxin TcdB"
                     /protein_id="HBH0240780.1"
                     /translation="KALKKFKEYLVTEVLELKNNNLTPVEKNLHFVWIGGQINDTAIN
                     YINQWKDVNSDYNVNVFYDSNAFLINTLKKTVVESAINDTLESFRENLNDPRFDYNKF
                     FRKRMEIIYDKQKNFINYYKAQREENPELIIDDIVKTYLSNEYSKEIDELNTYIEESL
                     NKITQNSGNDVRNFEEFKNGESFNLYEQELVERWNLAAASDILRISALKEIGGMYLDV
                     DMLPGIQPDLFESIEKPSSVTVDFWEMTKLEAIMKYKEYIPEYTSEHFDMLDEEVQSS
                     FESVLASKSDKSEIFSSLGDMEASPLEVKIAFNSKGIINQGLISVKDSYCSNLIVKQI
                     ENRYKILNNSLNPAISEDNDFNTTTNTFIDSIMAEANADNGRFMMELGKYLRVGFFPD
                     VKTTINLSGPEAYAAAYQDLLMFKEGSMNIHLIEADLRNFEISKTNISQSTEQEMASL
                     WSFDDARAKAQFEEYKRNYFEGSLGEDDNLDFSQNIVVDKEYLLEKISSLARSSERGY
                     IHYIVQLQGDKISYEAACNLFAKTPYDSVLFQKNIEDSEIAYYYNPGDGEIQEIDKYK
                     IPSIISDRPKIKLTFIGHGKDEFNTDIFAGFDVDSLSTEIEAAIDLAKEDISPKSIEI
                     NLLGCNMFSYSINVEETYPGKLLLKVKDKISELMPSISQDSIIVSANQYEVRINSEGR
                     RELLDHSGEWINKEESIIKDISSKEYISFNPKENKITVKSKNLPELSTLLQEIRNNSN
                     SSDIELEEKVMLTECEINVISNIDTQIVEERIEEAKNLTSDSINYIKDEFKLIESISD
                     ALCDLKQQNELEDSHFISFEDISETDEGFSIRFINKETGESIFVETEKTIFSEYANHI
                     TEEISKIKGTIFDTVNGKLVKKVNLDTTHEVNTLNAAFFIQSLIEYNSSKESLSNLSV
                     AMKVQVYAQLFSTGLNTITDAAKVVELVSTALDETIDLLPTLSEGLPIIATIIDGVSL
                     GAAIKELSETSDPLLRQEIEAKIGIMAVNLTTATTAIITSSLGVASGFSILLVPLAGI
                     SAGIPSLVNNELVLRDKATKVVDYFKHVSLVETEGVFTLLDDKIMMPQDDLVISEIDF
                     NNNSIVLGKCEIWRMEGGSGHTVTDDIDHFFSAPSITYREPHLSIYDVLEVQKEELDL
                     SKDLMVLPNAPNRVFAWETGWTPGLRSLENDGTKLLDRIRDNYEGEFYWRYFAFIADA
                     LITTLKPRYEDTNIRINLDSNTRSFIVPIITTEYIREKLSYSFYGSGGTYALSLSQYN
                     MGINIELSESDVWIIDVDNVVRDVTIESDKIKKGDLIEGILSTLSIEENKIILNSHEI
                     NFSGEVNGSNGFVSLTFSILEGINAIIEVDLLSKSYKLLISGELKILMLNSNHIQQKI
                     DYIGFNSELQKNIPYSFVDSEGKENGFINGSTKEGLFVSELPDVVLISKVYMDDSKPS
                     FGYYSNNLKDVKVITKDNVNILTGYYLKDDIKISLSLTLQDEKTIKLNSVHLDESGVA
                     EILKFMNRKGNTNTSDSLMSFLESMNIKSIFVNFLQSNIKFILDANFIISGTTSIGQF
                     EFICDENDNIQPYFIKFNTLETNYTLYVGNRQNMIVEPNYDLDDSGDISSTVINFSQK
                     YLYGIDSCVNKVVISPNIYTDEINITPVYETNNTYPEVIVLDANYINEKINVNINDLS
                     IRYVWSNDGNDFILMSTSEENKVSQVKIRFVNVFKDKTLANKLSFNFSDKQDVPVSEI
                     ILSFTPSYYEDGLIGYDLGLVSLYNEKFYINNFGMMVSGLIYINDSLYYFKPPVNNLI
                     TGFVTVGDDKYYFNPINGGAASIGETIIDDKNYYFNQSGVLQTGVFSTEDGFKYFAPA
                     NTLDENLEGEAIDFTGKLIIDENIYYFDDNYRGAVEWKELDGEMHYFSPETGKAFKGL
                     NQIGDYKYYFNSDGVMQKGFVSINDNKHYFDDSGVMKVGYTEIDGKHFYFAENGEMQI
                     GVFNTEDGFKYFAHHNEDLGNEEGEEISYSGILNFNNKIYYFDDSFTAVVGWKDLEDG
                     SKYYFDEDTAEAYIGLSLINDGQYYFNDDGIMQVGFVTINDKVFYFSDSGIIESGVQN
                     IDDNYFYIDDNGIVQIGVFDTSDGYKYFAPANTVNDNIYGQAVEYSGLVRVGEDVYYF
                     GETYTIETGWIYDMENESDKYYFNPETKKACKGINLIDDIKYYFDEKGIMRTGLISFE
                     NNNYYFNENGEMQFGYINIEDKMFYFGEDGVMQIGVFNTPDGFKYFAHQNTLDENFEG
                     ESINYTGWLDLDEKRYYFTDEYIAATGSVIIDGEEYYFDPDTAQLVISE"
     gene            7018..7518
                     /gene="tcdE"
                     /locus_tag="KR294_002716"
     CDS             7018..7518
                     /gene="tcdE"
                     /locus_tag="KR294_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holin-like glycosylating toxin export protein
                     TcdE"
                     /protein_id="HBH0240781.1"
                     /translation="MHSSSPFYISNGNKIFFYINLGGVMNMTISFLSEHIFIKLVILT
                     ISFDTLLGCLSAIKSRKFNSSFGIDGGIRKVAMIACIFFLSVVDILTKFNFLFMLPQD
                     CINFLRLKHLGISEFFSILFILYESVSILKNMCLCGLPVPKRLKEKIAILLDAMTDEM
                     NAKDEK"
     gene            7847..8029
                     /locus_tag="KR294_002717"
     CDS             7847..8029
                     /locus_tag="KR294_002717"
                     /inference="COORDINATES: protein motif:HMM:NF022413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240782.1"
                     /translation="MRDEGQNDIENKYQTLINDLIDSLKVIGKIYKEIKTLKKYKICL
                     QITIRQSPYLIEESIN"
     gene            8246..16378
                     /gene="tcdA"
                     /locus_tag="KR294_002718"
                     /gene_synonym="toxA"
     CDS             8246..16378
                     /gene="tcdA"
                     /locus_tag="KR294_002718"
                     /gene_synonym="toxA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021394011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin TcdA"
                     /protein_id="HBH0240783.1"
                     /translation="MSLISKEELIKLAYSIRPRENEYKTILTNLDEYNKLTTNNNENK
                     YLQLKKLNESIDVFMNKYKNSSRNRALSNLKKDILKEVILIKNSNTSPVEKNLHFVWI
                     GGEVSDIALEYIKQWADINAEYNIKLWYDSEAFLVNTLKKAIVESSTTEALQLLEEEI
                     QNPQFDNMKFYKKRMEFIYDRQKRFINYYKSQINKPTVPTIDDIIKSHLVSEYNRDET
                     LLESYRTNSLRKINSNHGIDIRANGLFTEQELLNIYSQELLNRGNLAAASDIVRLLAL
                     KNFGGVYLDVDMLPGIHSDLFKTISRPSSIGLDRWEMIKLEAIMKYKKYINNYTSENF
                     DKLDQQLKDNFKLIIESKSEKSEIFSKLENLNVSDLEIKIAFALGSVINQALISKQGS
                     YLTNLVIEQVKNRYQFLNQHLNPAIESDNNFTDTTKIFHDSLFNSATAENSMFLTKIA
                     PYLQVGFMPEARSTISLSGPGAYASAYYDFINLQENTIEKTLKASDLIEFKFPENNLS
                     QLTEQEINSLWSFDQASAKYQFEKYVRDYTGGSLSEDNGVDFNKNTALDKNYLLNNKI
                     PSNNVEEAGSKNYVHYIIQLQGDDISYEATCNLFSKNPKNSIIIQRNMNESAKSYFLS
                     DDGESILELNKYRIPERLKNKEKVKVTFIGHGKDEFNTSEFARLSVDSLSNEISSFLD
                     TIKLDISPKNVEVNLLGCNMFSYDFNVEETYPGKLLLSIMDKITSTLPDVNKNSITIG
                     ANQYEVRINSEGRKELLAHSGKWINKEEAIMSDLSSKEYIFFDSIDNKLKAKSKNIPG
                     LASISEDIKTLLLDASVSPDTKFILNNLKLNIESSIGDYIYYEKLEPVKNIIHNSIDD
                     LIDEFNLLENVSDELYELKKLNNLDEKYLISFEDISKNNSTYSVRFINKSNGESVYVE
                     TEKEIFSKYSEHITKEISTIKNSIITDVNGNLLDNIQLDHTSQVNTLNAAFFIQSLID
                     YSSNKDVLNDLSTSVKVQLYAQLFSTGLNTIYDSIQLVNLISNAVNDTINVLPTITEG
                     IPIVSTILDGINLGAAIKELLDEHDPLLKKELEAKVGVLAINMSLSIAATVASIVGIG
                     AEVTIFLLPIAGISAGIPSLVNNELILHDKATSVVNYFNHLSESKKYGPLKTEDDKIL
                     VPIDDLVISEIDFNNNSIKLGTCNILAMEGGSGHTVTGNIDHFFSSPSISSHIPSLSI
                     YSAIGIETENLDFSKKIMMLPNAPSRVFWWETGAVPGLRSLENDGTRLLDSIRDLYPG
                     KFYWRFYAFFDYAITTLKPVYEDTNIKIKLDKDTRNFIMPTITTNEIRNKLSYSFDGA
                     GGTYSLLLSSYPISTNINLSKDDLWIFNIDNEVREISIENGTIKKGKLIKDVLSKIDI
                     NKNKLIIGNQTIDFSGDIDNKDRYIFLTCELDDKISLIIEINLVAKSYSLLLSGDKNY
                     LISNLSNTIEKINTLGLDSKNIAYNYTDESNNKYFGAISKTSQKSIIHYKKDSKNILE
                     FYNDSTLEFNSKDFIAEDINVFMKDDINTITGKYYVDNNTDKSIDFSISLVSKNQVKV
                     NGLYLNESVYSSYLDFVKNSDGHHNTSNFMNLFLDNISFWKLFGFENINFVIDKYFTL
                     VGKTNLGYVEFICDNNKNIDIYFGEWKTSSSKSTIFSGNGRNVVVEPIYNPDTGEDIS
                     TSLDFSYEPLYGIDRYINKVLIAPDLYTSLININTNYYSNEYYPEIIVLNPNTFHKKV
                     NINLDSSSFEYKWSTEGSDFILVRYLEESNKKILQKIRIKGILSNTQSFNKMSIDFKD
                     IKKLSLGYIMSNFKSFNSENELDRDHLGFKIIDNKTYYYDEDSKLVKGLININNSLFY
                     FDPIEFNLVTGWQTINGKKYYFDINTGAALTSYKIINGKHFYFNNDGVMQLGVFKGPD
                     GFEYFAPANTQNNNIEGQAIVYQSKFLTLNGKKYYFDNNSKAVTGWRIINNEKYYFNP
                     NNAIAAVGLQVIDNNKYYFNPDTAIISKGWQTVNGSRYYFDTDTAIAFNGYKTIDGKH
                     FYFDSDCVVKIGVFSTSNGFEYFAPANTYNNNIEGQAIVYQSKFLTLNGKKYYFDNNS
                     KAVTGWQTIDSKKYYFNTNTAEAATGWQTIDGKKYYFNTNTAEAATGWQTIDGKKYYF
                     NTNTAIASTGYTIINGKHFYFNTDGIMQIGVFKGPNGFEYFAPANTDANNIEGQAILY
                     QNEFLTLNGKKYYFGSDSKAVTGWRIINNKKYYFNPNNAIAAIHLCTINNDKYYFSYD
                     GILQNGYITIERNNFYFDANNESKMVTGVFKGPNGFEYFAPANTHNNNIEGQAIVYQN
                     KFLTLNGKKYYFDNDSKAVTGWQTIDGKKYYFNLNTAEAATGWQTIDGKKYYFNLNTA
                     EAATGWQTIDGKKYYFNTNTFIASTGYTSINGKHFYFNTDGIMQIGVFKGPNGFEYFA
                     PANTDANNIEGQAILYQNKFLTLNGKKYYFGSDSKAVTGLRTIDGKKYYFNTNTAVAV
                     TGWQTINGKKYYFNTNTSIASTGYTIISGKHFYFNTDGIMQIGVFKGPDGFEYFAPAN
                     TDANNIEGQAIRYQNRFLYLHDNIYYFGNNSKAATGWVTIDGNRYYFEPNTAMGANGY
                     KTIDNKNFYFRNGLPQIGVFKGSNGFEYFAPANTDANNIEGQAIRYQNRFLHLLGKIY
                     YFGNNSKAVTGWQTINGKVYYFMPDTAMAAAGGLFEIDGVIYFFGVDGVKAPGIYG"
     gene            complement(16713..17411)
                     /gene="tcdC"
                     /locus_tag="KR294_002719"
     CDS             complement(16713..17411)
                     /gene="tcdC"
                     /locus_tag="KR294_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin anti-sigma factor TcdC"
                     /protein_id="HBH0240784.1"
                     /translation="MFSKKNEGNEFSNEGKGSSKKIIKFFKSTKGIALLAFILGVFFG
                     NISSPACSEDHEEVISNQTSVIDSQKTEIETLNSKLSDAEPWFKMKDDEKKAIEAENQ
                     RKAEEAKKAEEAKKAEEQRKKEEEEKKGYDTGITYDQLARTPDDYKYKKVKFEGKVIQ
                     VIEDGDEVQIRLAVSGNYDKVVLCSYKKSITPSRVLEDDYITIRGISAGTITYESTMG
                     GNITIPGIAVEKIN"
     gene            17837..18082
                     /locus_tag="KR294_002720"
     CDS             17837..18082
                     /locus_tag="KR294_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pathogenicity locus"
                     /protein_id="HBH0240785.1"
                     /translation="MGELQKIPGVGKATEKSLIMLGYTTIKSLKDANPAQMYEKECLM
                     RGQHIDRCQLYVYRCAVYFASTENPEPEKLKWWYWKD"
     gene            complement(18300..18569)
                     /locus_tag="KR294_002721"
     CDS             complement(18300..18569)
                     /locus_tag="KR294_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HBH0240786.1"
                     /translation="MFESRCGVCCDSCTKKEQVNCTGCPTMEKPFWGGECKVKTCCES
                     KELNHCGECDTFPCDMLLNKGKDQGFDPMVNIEQCRKWLEETVSN"
BASE COUNT         7526 a         2206 c         2918 g         6458 t
ORIGIN      
        1 ataaagcctt aaaaaaattt aaggaatatc tagttacaga agtattagag ctaaagaata
       61 ataatttaac tccagttgag aaaaatttac attttgtttg gattggaggt caaataaatg
      121 acactgctat taattatata aatcaatgga aagatgtaaa tagtgattat aatgttaatg
      181 ttttttatga tagtaatgca tttttgataa acacattgaa aaaaactgta gtagaatcag
      241 caataaatga tacacttgaa tcatttagag aaaacttaaa tgaccctaga tttgactata
      301 ataaattctt cagaaaacgt atggaaataa tttatgataa acagaaaaat ttcataaact
      361 actataaagc tcaaagagaa gaaaatcctg aacttataat tgatgatatt gtaaagacat
      421 atctttcaaa tgagtattca aaggagatag atgaacttaa tacctatatt gaagaatcct
      481 taaataaaat tacacagaat agtggaaatg atgttagaaa ctttgaagaa tttaaaaatg
      541 gagagtcatt caacttatat gaacaagagt tggtagaaag gtggaattta gctgctgctt
      601 ctgacatatt aagaatatct gcattaaaag aaattggtgg tatgtattta gatgttgata
      661 tgttaccagg aatacaacca gacttatttg agtctataga gaaacctagt tcagtaacag
      721 tggatttttg ggaaatgaca aagttagaag ctataatgaa atacaaagaa tatataccag
      781 aatatacctc agaacatttt gacatgttag acgaagaagt tcaaagtagt tttgaatctg
      841 ttctagcttc taagtcagat aaatcagaaa tattctcatc acttggtgat atggaggcat
      901 caccactaga agttaaaatt gcatttaata gtaagggtat tataaatcaa gggctaattt
      961 ctgtgaaaga ctcatattgt agcaatttaa tagtaaaaca aatcgagaat agatataaaa
     1021 tattgaataa tagtttaaat ccagctatta gcgaggataa tgattttaat actacaacga
     1081 atacctttat tgatagtata atggctgaag ctaatgcaga taatggtaga tttatgatgg
     1141 aactaggaaa gtatttaaga gttggtttct tcccagatgt taaaactact attaacttaa
     1201 gtggccctga agcatatgcg gcagcttatc aagatttatt aatgtttaaa gaaggcagta
     1261 tgaatatcca tttgatagaa gctgatttaa gaaactttga aatctctaaa actaatattt
     1321 ctcaatcaac tgaacaagaa atggctagct tatggtcatt tgacgatgca agagctaaag
     1381 ctcaatttga agaatataaa aggaattatt ttgaaggttc tcttggtgaa gatgataatc
     1441 ttgatttttc tcaaaatata gtagttgaca aggagtatct tttagaaaaa atatcttcat
     1501 tagcaagaag ttcagagaga ggatatatac actatattgt tcagttacaa ggagataaaa
     1561 ttagttatga agcagcatgt aacttatttg caaagactcc ttatgatagt gtactgtttc
     1621 agaaaaatat agaagattca gaaattgcat attattataa tcctggagat ggtgaaatac
     1681 aagaaataga caagtataaa attccaagta taatttctga tagacctaag attaaattaa
     1741 catttattgg tcatggtaaa gatgaattta atactgatat atttgcaggt tttgatgtag
     1801 attcattatc cacagaaata gaagcagcaa tagatttagc taaagaggat atttctccta
     1861 agtcaataga aataaattta ttaggatgta atatgtttag ctactctatc aacgtagagg
     1921 agacttatcc tggaaaatta ttacttaaag ttaaagataa aatatcagaa ttaatgccat
     1981 ctataagtca agactctatt atagtaagtg caaatcaata tgaagttaga ataaatagtg
     2041 aaggaagaag agaattattg gatcattctg gtgaatggat aaataaagaa gaaagtatta
     2101 taaaggatat ttcatcaaaa gaatatatat catttaatcc taaagaaaat aaaattacag
     2161 taaaatctaa aaatttacct gagctatcta cattattaca agaaattaga aataattcta
     2221 attcaagtga tattgaacta gaagaaaaag taatgttaac agaatgtgag ataaatgtta
     2281 tttcaaatat agatacgcaa attgttgagg aaaggattga agaagctaag aatttaactt
     2341 ctgactctat taattatata aaagatgaat ttaaactaat agaatctatt tctgatgcac
     2401 tatgtgactt aaaacaacag aatgaattag aagattctca ttttatatct tttgaggaca
     2461 tatcagagac tgatgaggga tttagtataa gatttattaa taaagaaact ggagaatcta
     2521 tatttgtaga aactgaaaaa acaatattct ctgaatatgc taatcatata actgaagaga
     2581 tttctaagat aaaaggtact atatttgata ctgtaaatgg taagttagta aaaaaagtaa
     2641 atttagatac tacacacgaa gtaaatactt taaatgctgc attttttata caatcattaa
     2701 tagaatataa tagttctaaa gaatctctta gtaatttaag tgtagcaatg aaagtccaag
     2761 tttacgctca attatttagt actggtttaa atactattac agatgcagcc aaagttgttg
     2821 aattagtatc aactgcatta gatgaaacta tagacttact tcctacatta tctgaaggat
     2881 tacctataat tgcaactatt atagatggtg taagtttagg tgcagcaatc aaagagctaa
     2941 gtgaaacgag tgacccatta ttaagacaag aaatagaagc taagataggt ataatggcag
     3001 taaatttaac aacagctaca actgcaatca ttacttcatc tttgggggta gctagtggat
     3061 ttagtatact tttagttcct ttagcaggaa tttcagcagg tataccaagc ttagtaaaca
     3121 atgaacttgt acttcgagat aaggcaacaa aggttgtaga ttattttaaa catgtttcat
     3181 tagttgaaac tgaaggagta tttactttat tagatgataa aataatgatg ccacaagatg
     3241 atttagtgat atcagaaata gattttaata ataattcaat agttttaggt aaatgtgaaa
     3301 tctggagaat ggaaggtggt tcaggtcata ctgtaactga tgatatagat cacttctttt
     3361 cagcaccatc aataacatat agagagccac acttatctat atatgacgta ttggaagtac
     3421 aaaaagaaga acttgatttg tcaaaagatt taatggtatt acctaatgct ccaaatagag
     3481 tatttgcttg ggaaacagga tggacaccag gtttaagaag cttagaaaat gatggcacaa
     3541 aactgttaga ccgtataaga gataactatg aaggtgagtt ttattggaga tattttgctt
     3601 ttatagctga tgctttaata acaacattaa aaccaagata tgaagatact aatataagaa
     3661 taaatttaga tagtaatact agaagtttta tagttccaat aataactaca gaatatataa
     3721 gagaaaaatt atcatattct ttctatggtt caggaggaac ttatgcattg tctctttctc
     3781 aatataatat gggtataaat atagaattaa gtgaaagtga tgtttggatt atagatgttg
     3841 ataatgttgt gagagatgta actatagaat ctgataaaat taaaaaaggt gatttaatag
     3901 aaggtatttt atctacacta agtattgaag agaataaaat tatcttaaat agccatgaga
     3961 ttaatttttc tggtgaggta aatggaagta atggatttgt ttctttaaca ttttcaattt
     4021 tagaaggaat aaatgcaatt atagaagttg atttattatc taaatcatat aaattactta
     4081 tttctggcga attaaaaata ttgatgttaa attcaaatca tattcaacag aaaatagatt
     4141 atataggatt caatagcgaa ttacagaaaa atataccata tagctttgta gatagtgaag
     4201 gaaaagagaa tggttttatt aatggttcaa caaaagaagg tttatttgta tctgaattac
     4261 ctgatgtagt tcttataagt aaggtttata tggatgatag taagccttca tttggatatt
     4321 atagtaataa tttgaaagat gtcaaagtta taactaaaga taatgttaat atattaacag
     4381 gttattatct taaggatgat ataaaaatct ctctttcttt gactctacaa gatgaaaaaa
     4441 ctataaagtt aaatagtgtg catttagatg aaagtggagt agctgagatt ttgaagttca
     4501 tgaatagaaa aggtaataca aatacttcag attctttaat gagcttttta gaaagtatga
     4561 atataaaaag tattttcgtt aatttcttac aatctaatat taagtttata ttagatgcta
     4621 attttataat aagtggtact acttctattg gccaatttga gtttatttgt gatgaaaatg
     4681 ataatataca accatatttc attaagttta atacactaga aactaattat actttatatg
     4741 taggaaatag acaaaatatg atagtggaac caaattatga tttagatgat tctggagata
     4801 tatcttcaac tgttatcaat ttctctcaaa agtatcttta tggaatagac agttgtgtta
     4861 ataaagttgt aatttcacca aatatttata cagatgaaat aaatataacg cctgtatatg
     4921 aaacaaataa tacttatcca gaagttattg tattagatgc aaattatata aatgaaaaaa
     4981 taaatgttaa tatcaatgat ctatctatac gatatgtatg gagtaatgat ggtaatgatt
     5041 ttattcttat gtcaactagt gaagaaaata aggtgtcaca agttaaaata agattcgtta
     5101 atgtttttaa agataagact ttggcaaata agctatcttt taactttagt gataaacaag
     5161 atgtacctgt aagtgaaata atcttatcat ttacaccttc atattatgag gatggattga
     5221 ttggctatga tttgggtcta gtttctttat ataatgagaa attttatatt aataactttg
     5281 gaatgatggt atctggatta atatatatta atgattcatt atattatttt aaaccaccag
     5341 taaataattt gataactgga tttgtgactg taggcgatga taaatactac tttaatccaa
     5401 ttaatggtgg agctgcttca attggagaga caataattga tgacaaaaat tattatttca
     5461 accaaagtgg agtgttacaa acaggtgtat ttagtacaga agatggattt aaatattttg
     5521 ccccagctaa tacacttgat gaaaacctag aaggagaagc aattgatttt actggaaaat
     5581 taattattga cgaaaatatt tattattttg atgataatta tagaggagct gtagaatgga
     5641 aagaattaga tggtgaaatg cactatttta gcccagaaac aggtaaagct tttaaaggtc
     5701 taaatcaaat aggtgattat aaatactatt tcaattctga tggagttatg caaaaaggat
     5761 ttgttagtat aaatgataat aaacactatt ttgatgattc tggtgttatg aaagtaggtt
     5821 acactgaaat agatggcaag catttctact ttgctgaaaa cggagaaatg caaataggag
     5881 tatttaatac agaagatgga tttaaatatt ttgctcatca taatgaagat ttaggaaatg
     5941 aagaaggtga agaaatctca tattctggta tattaaattt caataataaa atttactatt
     6001 ttgatgattc atttacagct gtagttggat ggaaagattt agaggatggt tcaaagtatt
     6061 attttgatga agatacagca gaagcatata taggtttgtc attaataaat gatggtcaat
     6121 attattttaa tgatgatgga attatgcaag ttggatttgt cactataaat gataaagtct
     6181 tctacttctc tgactctgga attatagaat ctggagtaca aaacatagat gacaattatt
     6241 tctatataga tgataatggt atagttcaaa ttggtgtatt tgatacttca gatggatata
     6301 aatattttgc acctgctaat actgtaaatg ataatattta cggacaagca gttgaatata
     6361 gtggtttagt tagagttggg gaagatgtat attattttgg agaaacatat acaattgaga
     6421 ctggatggat atatgatatg gaaaatgaaa gtgataaata ttatttcaat ccagaaacta
     6481 aaaaagcatg caaaggtatt aatttaattg atgatataaa atattatttt gatgagaagg
     6541 gcataatgag aacgggtctt atatcatttg aaaataataa ttattacttt aatgagaatg
     6601 gtgaaatgca atttggttat ataaatatag aagataagat gttctatttt ggtgaagatg
     6661 gtgtcatgca gattggagta tttaatacac cagatggatt taaatacttt gcacatcaaa
     6721 atactttgga tgagaatttt gagggagaat caataaacta tactggttgg ttagatttag
     6781 atgaaaagag atattatttt acagatgaat atattgcagc aactggttca gttattattg
     6841 atggtgagga gtattatttt gatcctgata cagctcaatt agtgattagt gaatagataa
     6901 aaatatgtta aatatatcct cttatactta aatatataaa aataaacaaa atgatacact
     6961 acataaagtg ttctatctaa tatgaagatt taccaataaa aaggtggact atgatgaatg
     7021 cacagtagtt caccttttta tatttctaat ggtaacaaaa tattttttta tataaaccta
     7081 ggaggcgtta tgaatatgac aatatctttt ttatcagagc atatatttat aaagttagta
     7141 attttaacta tatcatttga tacattatta ggatgtttaa gtgcaataaa aagtcgtaaa
     7201 tttaattcta gttttggaat agatggagga atcagaaaag tagcaatgat agcatgtata
     7261 ttttttttat cagtagttga cattcttaca aagtttaact ttttatttat gttaccacaa
     7321 gattgtatca attttttaag actaaaacat cttggaatat ctgaattttt ctctatttta
     7381 tttattttat atgaaagtgt aagtatatta aaaaatatgt gcttatgtgg attaccagta
     7441 cctaagagat taaaggaaaa aatagcaatt ttactagatg caatgacaga tgaaatgaat
     7501 gctaaggatg aaaagtaagt aatggtagat ataataaaga tattaacaaa taaaaagtgt
     7561 tatccaaata agaatagctg aaagttatca taattcatga aactaataat gaaaacgagg
     7621 gagcagatgc caagagacac acaagtatta aatacatata atttcgaagc aagtgttcat
     7681 tactatatag atgacaaggt agtatatcaa acattggttc acaaagatgg tgcatggtca
     7741 gttggtaaaa tctattaagc tacattagtt acagatatca caaactataa tagttaaaca
     7801 tagaaatatg tgtaaattgt gatggaaatt attcaaaaac acaaaaatac gtgatgaagg
     7861 acaaaatgat atagaaaata agtatcaaac cttaataaat gatttaattg atagtttaaa
     7921 agttatagga aaaatatata aagaaataaa aacattaaaa aaatataaga tatgtttaca
     7981 aattactatc agacaatctc cttatctaat agaagagtca attaactaat tgagtatctt
     8041 taaattgaaa tgttaggaag tgatttaaat atgaaaactt aaattataaa aaatcaatat
     8101 taatttattt ttaaaaaata gaaaggagtg tataagattt attttcaaag tttaaaaaca
     8161 agaaaatcaa tttaaatttc agaaggaata aatgtggtta tagaagtgga tttattatca
     8221 aaaataataa tactaggagg tttttatgtc tttaatatct aaagaagagt taataaaact
     8281 cgcatatagc attagaccaa gagaaaatga gtataaaact atactaacta atttagacga
     8341 atataataag ttaactacaa acaataatga aaataaatat ttacaattaa aaaaactaaa
     8401 tgaatcaatt gatgttttta tgaataaata taaaaattca agcagaaata gagcactctc
     8461 taatctaaaa aaagatatat taaaagaagt aattcttatt aaaaattcca atacaagtcc
     8521 tgtagaaaaa aatttacatt ttgtatggat aggtggagaa gtcagtgata ttgctcttga
     8581 atacataaaa caatgggctg atattaatgc agaatataat attaaactgt ggtatgatag
     8641 tgaagcgttc ttagtcaata cactaaaaaa ggctatagtt gagtcttcta ccactgaagc
     8701 attacagcta ctagaagaag agattcaaaa tcctcaattt gataatatga aattttacaa
     8761 aaaaaggatg gaatttatat atgatagaca aaaaaggttt ataaattatt ataaatctca
     8821 aatcaataaa cctacagtac ctacaataga tgatattata aagtctcatc tagtatctga
     8881 atataataga gatgaaactt tattagaatc atatagaaca aattctttga gaaaaataaa
     8941 tagtaaccat gggatagata tcagagctaa tggcttgttt acagaacaag agttattaaa
     9001 tatttatagt caggagttgt taaatcgtgg aaatttagct gcagcatctg acatagtaag
     9061 attattagca ctaaaaaatt ttggcggagt atatttagat gttgatatgc ttccaggtat
     9121 tcactctgat ttatttaaaa caatatctag acctagctct attggactag accgttggga
     9181 aatgataaaa ttagaggcta ttatgaagta taaaaaatat ataaataatt atacatcaga
     9241 aaactttgat aaacttgatc aacaattaaa agataatttt aaactcatta tagaaagtaa
     9301 aagtgaaaaa tctgagatat tttctaaatt agaaaattta aatgtatctg atcttgaaat
     9361 taaaatagct ttcgctttag gcagtgttat aaatcaagcc ttgatatcaa aacaaggttc
     9421 atatcttact aacctagtaa tagaacaagt aaaaaataga tatcaatttt taaaccaaca
     9481 ccttaaccca gccatagagt ctgataataa cttcacagat actactaaaa tttttcatga
     9541 ttcattattt aattcagcta ccgcagaaaa ctctatgttt ttaacaaaaa tagcaccata
     9601 cttacaagta ggttttatgc cagaagctcg ctccacaata agtttaagtg gtccaggagc
     9661 ttatgcatca gcttactatg atttcataaa tttacaagaa aatactatag aaaaaacttt
     9721 aaaagcatca gatttaatag aatttaaatt cccagaaaat aatctatctc aattgacaga
     9781 acaagaaata aatagtctat ggagctttga tcaagcaagt gcaaaatatc aatttgagaa
     9841 atatgtaaga gattatactg gtggatctct ttctgaagac aatggggtag actttaataa
     9901 aaatactgcc ctcgacaaaa actatttatt aaataataaa attccatcaa acaatgtaga
     9961 agaagctgga agtaaaaatt atgttcatta tatcatacag ttacaaggag atgatataag
    10021 ttatgaagca acatgcaatt tattttctaa aaatcctaaa aatagtatta ttatacaacg
    10081 aaatatgaat gaaagtgcaa aaagctactt tttaagtgat gatggagaat ctattttaga
    10141 attaaataaa tataggatac ctgaaagatt aaaaaataag gaaaaagtaa aagtaacctt
    10201 tattggacat ggtaaagatg aattcaacac aagcgaattt gctagattaa gtgtagattc
    10261 actttccaat gagataagtt catttttaga taccataaaa ttagatatat cacctaaaaa
    10321 tgtagaagta aacttacttg gatgtaatat gtttagttat gattttaatg ttgaagaaac
    10381 ttatcctggg aagttgctat taagtattat ggacaaaatt acttccactt tacctgatgt
    10441 aaataaaaat tctattacta taggagcaaa tcaatatgaa gtaagaatta atagtgaggg
    10501 aagaaaagaa cttctggctc actcaggtaa atggataaat aaagaagaag ctattatgag
    10561 cgatttatct agtaaagaat acattttttt tgattctata gataataagc taaaagcaaa
    10621 gtccaagaat attccaggat tagcatcaat atcagaagat ataaaaacat tattacttga
    10681 tgcaagtgtt agtcctgata caaaatttat tttaaataat cttaagctta atattgaatc
    10741 ttctattggt gattacattt attatgaaaa attagagcct gttaaaaata taattcacaa
    10801 ttctatagat gatttaatag atgagttcaa tctacttgaa aatgtatctg atgaattata
    10861 tgaattaaaa aaattaaata atctagatga gaagtattta atatcttttg aagatatctc
    10921 aaaaaataat tcaacttact ctgtaagatt tattaacaaa agtaatggtg agtcagttta
    10981 tgtagaaaca gaaaaagaaa ttttttcaaa atatagcgaa catattacaa aagaaataag
    11041 tactataaag aatagtataa ttacagatgt taatggtaat ttattggata atatacagtt
    11101 agatcatact tctcaagtta atacattaaa cgcagcattc tttattcaat cattaataga
    11161 ttatagtagc aataaagatg tactgaatga tttaagtacc tcagttaagg ttcaacttta
    11221 tgctcaacta tttagtacag gtttaaatac tatatatgac tctatccaat tagtaaattt
    11281 aatatcaaat gcagtaaatg atactataaa tgtactacct acaataacag aggggatacc
    11341 tattgtatct actatattag acggaataaa cttaggtgca gcaattaagg aattactaga
    11401 cgaacatgac ccattactaa aaaaagaatt agaagctaag gtgggtgttt tagcaataaa
    11461 tatgtcatta tctatagctg caactgtagc ttcaattgtt ggaataggtg ctgaagttac
    11521 tattttctta ttacctatag ctggtatatc tgcaggaata ccttcattag ttaataatga
    11581 attaatattg catgataagg caacttcagt ggtaaactat tttaatcatt tgtctgaatc
    11641 taaaaaatat ggccctctta aaacagaaga tgataaaatt ttagttccta ttgatgattt
    11701 agtaatatca gaaatagatt ttaataataa ttcgataaaa ctaggaacat gtaatatatt
    11761 agcaatggag gggggatcag gacacacagt gactggtaat atagatcact ttttctcatc
    11821 tccatctata agttctcata ttccttcatt atcaatttat tctgcaatag gtatagaaac
    11881 agaaaatcta gatttttcaa aaaaaataat gatgttacct aatgctcctt caagagtgtt
    11941 ttggtgggaa actggagcag ttccaggttt aagatcattg gaaaatgacg gaactagatt
    12001 acttgattca ataagagatt tatacccagg taaattttac tggagattct atgctttttt
    12061 cgattatgca ataactacat taaaaccagt ttatgaagac actaatatta aaattaaact
    12121 agataaagat actagaaact tcataatgcc aactataact actaacgaaa ttagaaacaa
    12181 attatcttat tcatttgatg gagcaggagg aacttactct ttattattat cttcatatcc
    12241 aatatcaacg aatataaatt tatctaaaga tgatttatgg atatttaata ttgataatga
    12301 agtaagagaa atatctatag aaaatggtac tattaaaaaa ggaaagttaa taaaagatgt
    12361 tttaagtaaa attgatataa ataaaaataa acttattata ggcaatcaaa caatagattt
    12421 ttcaggcgat atagataata aagatagata tatattcttg acttgtgagt tagatgataa
    12481 aattagttta ataatagaaa taaatcttgt tgcaaaatct tatagtttgt tattgtctgg
    12541 ggataaaaat tatttgatat ccaatttatc taatactatt gagaaaatca atactttagg
    12601 cctagatagt aaaaatatag cgtacaatta cactgatgaa tctaataata aatattttgg
    12661 agctatatct aaaacaagtc aaaaaagcat aatacattat aaaaaagaca gtaaaaatat
    12721 attagaattt tataatgaca gtacattaga atttaacagt aaagatttta ttgctgaaga
    12781 tataaatgta tttatgaaag atgatattaa tactataaca ggaaaatact atgttgataa
    12841 taatactgat aaaagtatag atttctctat ttctttagtt agtaaaaatc aagtaaaagt
    12901 aaatggatta tatttaaatg aatccgtata ctcatcttac cttgattttg tgaaaaattc
    12961 agatggacac cataatactt ctaattttat gaatttattt ttggacaata taagtttctg
    13021 gaaattgttt gggtttgaaa atataaattt tgtaatcgat aaatacttta cccttgttgg
    13081 taaaactaat cttggatatg tagaatttat ttgtgacaat aataaaaata tagatatata
    13141 ttttggtgaa tggaaaacat cgtcatctaa aagcactata tttagcggaa atggtagaaa
    13201 tgttgtagta gagcctatat ataatcctga tacgggtgaa gatatatcta cttcactaga
    13261 tttttcctat gaacctctct atggaataga tagatatata aataaagtat tgatagcacc
    13321 tgatttatat acaagtttaa taaatattaa taccaattat tattcaaatg agtactaccc
    13381 tgagattata gttcttaacc caaatacatt ccacaaaaaa gtaaatataa atttagatag
    13441 ttcttctttt gagtataaat ggtctacaga aggaagtgac tttattttag ttagatactt
    13501 agaagaaagt aataaaaaaa tattacaaaa aataagaatc aaaggtatct tatctaatac
    13561 tcaatcattt aataaaatga gtatagattt taaagatatt aaaaaactat cattaggata
    13621 tataatgagt aattttaaat catttaattc tgaaaatgaa ttagatagag atcatttagg
    13681 atttaaaata atagataata aaacttatta ctatgatgaa gatagtaaat tagttaaagg
    13741 attaatcaat ataaataatt cattattcta ttttgatcct atagaattta acttagtaac
    13801 tggatggcaa actatcaatg gtaaaaaata ttattttgat ataaatactg gagcagcttt
    13861 aactagttat aaaattatta atggtaaaca cttttatttt aataatgatg gtgtgatgca
    13921 gttgggagta tttaaaggac ctgatggatt tgaatatttt gcacctgcca atactcaaaa
    13981 taataacata gaaggtcagg ctatagttta tcaaagtaaa ttcttaactt tgaatggcaa
    14041 aaaatattat tttgataata actcaaaagc agtcactgga tggagaatta ttaacaatga
    14101 gaaatattac tttaatccta ataatgctat tgctgcagtc ggattgcaag taattgacaa
    14161 taataagtat tatttcaatc ctgacactgc tatcatctca aaaggttggc agactgttaa
    14221 tggtagtaga tactactttg atactgatac cgctattgcc tttaatggtt ataaaactat
    14281 tgatggtaaa cacttttatt ttgatagtga ttgtgtagtg aaaataggtg tgtttagtac
    14341 ctctaatgga tttgaatatt ttgcacctgc taatacttat aataataaca tagaaggtca
    14401 ggctatagtt tatcaaagta aattcttaac tttgaatggt aaaaaatatt actttgataa
    14461 taactcaaaa gcagttaccg gatggcaaac tattgatagt aaaaaatatt actttaatac
    14521 taacactgct gaagcagcta ctggatggca aactattgat ggtaaaaaat attactttaa
    14581 tactaacact gctgaagcag ctactggatg gcaaactatt gatggtaaaa aatattactt
    14641 taatactaac actgctatag cttcaactgg ttatacaatt attaatggta aacattttta
    14701 ttttaatact gatggtatta tgcagatagg agtgtttaaa ggacctaatg gatttgaata
    14761 ttttgcacct gctaatacgg atgctaacaa catagaaggt caagctatac tttaccaaaa
    14821 tgaattctta actttgaatg gtaaaaaata ttactttggt agtgactcaa aagcagttac
    14881 tggatggaga attattaaca ataagaaata ttactttaat cctaataatg ctattgctgc
    14941 aattcatcta tgcactataa ataatgacaa gtattacttt agttatgatg gaattcttca
    15001 aaatggatat attactattg aaagaaataa tttctatttt gatgctaata atgaatctaa
    15061 aatggtaaca ggagtattta aaggacctaa tggatttgag tattttgcac ctgctaatac
    15121 tcacaataat aacatagaag gtcaggctat agtttaccag aacaaattct taactttgaa
    15181 tggcaaaaaa tattattttg ataatgactc aaaagcagtt actggatggc aaaccattga
    15241 tggtaaaaaa tattacttta atcttaacac tgctgaagca gctactggat ggcaaactat
    15301 tgatggtaaa aaatattact ttaatcttaa cactgctgaa gcagctactg gatggcaaac
    15361 tattgatggt aaaaaatatt actttaatac taacactttc atagcctcaa ctggttatac
    15421 aagtattaat ggtaaacatt tttattttaa tactgatggt attatgcaga taggagtgtt
    15481 taaaggacct aatggatttg aatactttgc acctgctaat acggatgcta acaacataga
    15541 aggtcaagct atactttacc aaaataaatt cttaactttg aatggtaaaa aatattactt
    15601 tggtagtgac tcaaaagcag ttaccggatt gcgaactatt gatggtaaaa aatattactt
    15661 taatactaac actgctgttg cagttactgg atggcaaact attaatggta aaaaatacta
    15721 ctttaatact aacacttcta tagcttcaac tggttataca attattagtg gtaaacattt
    15781 ttattttaat actgatggta ttatgcagat aggagtgttt aaaggacctg atggatttga
    15841 atactttgca cctgctaata cagatgctaa caatatagaa ggtcaagcta tacgttatca
    15901 aaatagattc ctatatttac atgacaatat atattatttt ggtaataatt caaaagcggc
    15961 tactggttgg gtaactattg atggtaatag atattacttc gagcctaata cagctatggg
    16021 tgcgaatggt tataaaacta ttgataataa aaatttttac tttagaaatg gtttacctca
    16081 gataggagtg tttaaagggt ctaatggatt tgaatacttt gcacctgcta atacggatgc
    16141 taacaatata gaaggtcaag ctatacgtta tcaaaataga ttcctacatt tacttggaaa
    16201 aatatattac tttggtaata attcaaaagc agttactgga tggcaaacta ttaatggtaa
    16261 agtatattac tttatgcctg atactgctat ggctgcagct ggtggacttt tcgagattga
    16321 tggtgttata tatttctttg gtgttgatgg agtaaaagcc cctgggatat atggctaaaa
    16381 tatatgtttg ataaaaaatt attcctgtgc tactaagaaa ttatttttat ataataaata
    16441 ttgagattta attaaaagtc atgtgttatt gtaatacatg acttttagtt aaaatttttc
    16501 tatcatttaa taatctatta ttcttgacta ttttataata aaattcatat atggaaatat
    16561 taatactaaa taattaatag ttgataaaaa atagataata tgctaaaagc aaaaactaat
    16621 ttagagcctt gtaactgttt atttgcaatt ataaaaacat ctttaaacat attgactata
    16681 atataaaata ttaactataa tacaaaacaa tattaattaa ttttctctac agctatccct
    16741 ggtatagtta tatttccacc catagttgat tcataagtta tagttccagc acttatacct
    16801 cttatagtta tgtaatcatc ctctaatact cttgaaggag ttattgattt tttataacta
    16861 catagtacaa ccttatcata atttccagac acagctaatc ttatttgcac ctcatcacca
    16921 tcttcaataa cttgaataac cttaccttca aattttacct ttttgtactt ataatcatca
    16981 ggtgttctag ctaattggtc ataagtaata ccagtatcat atcctttctt ctcctcttct
    17041 tcttttttgc gttgttcttc agccttttta gcttcttcag cttttttagc ttcttcagct
    17101 ttacgttgat tttcagcttc aatagctttc ttttcgtcgt ctttcatttt gaaccatggt
    17161 tcagcatcag acaatttgct atttaaagtt tctatttctg ttttttgaga atctataact
    17221 gatgtttggt tagaaatgac ctcctcatgg tcttcagaac aagctggtga ggatatattg
    17281 ccaaaaaaca cgcctaaaat aaatgccagt agagcaatac cctttgtgct cttaaagaat
    17341 ttaattattt tcttagagct tccttttcct tcattactaa attcgttacc ctcatttttt
    17401 ttagaaaaca taatacaatc tcccttttat tagatatatt ttattttaaa agttaaaaac
    17461 ttaaaataac tagttgacta aaaattatat attcatattt tcctaaaata tatttcccct
    17521 aagcataatt ttacaaaata aagtaagaag attcaatata ttttgagaaa ataagataaa
    17581 aatgtcagat tataatataa ttttcttgaa ggtgaatttt atatattaaa ttaaacataa
    17641 agtattttat ttgtataaaa ctatattatg atgtaattaa gtgactcagt gatttagagg
    17701 tggtaaaata tatatatatg aaagagcata aataaattga tataataaaa aattaaatat
    17761 taaatattaa ctataataaa aaaatatctg gtaataggta taatataaaa agaatatacc
    17821 agaaagaagg tgaagtatgg gagaactaca aaaaattcca ggggtaggga aagcaacaga
    17881 aaaatcttta atcatgttag gatatacaac tattaaatca cttaaagatg caaacccagc
    17941 acaaatgtat gaaaaggaat gtttaatgcg tggacagcac atagacagat gtcagttata
    18001 tgtatacaga tgtgcagtat attttgcatc aactgaaaat ccagaaccag aaaaattaaa
    18061 gtggtggtat tggaaagatt aaaaaatcaa aaaagttaga cataaaaaag agttgaatat
    18121 ccgttttaaa taataaaaac taatactcaa ctctttttta gtcgtaaatt ttatgtaaat
    18181 ctatttgtat ggctaaatat acccatcaat aaatgtataa atataccaat caacaaatga
    18241 ctaaacatac tacctaacaa aggattaaat aaattactta acaaagcatt ctaaaacaat
    18301 taattagaaa ctgtttcttc aagccatttt ctacattgct caatatttac catagggtca
    18361 aaaccttggt cttttccctt atttaaaagc atatcacaag ggaaagtatc acattcacca
    18421 caatgattaa gttccttact ttcacagcaa gttttaacct tacattctcc accccaaaat
    18481 ggtttttcca tagttgggca accagtgcaa tttacttgtt ctttttttgt acaactgtca
    18541 caacagacac cacatcttga ttcaaacatg ttcaaacatc ctttccatta tttaaaaata
    18601 ttataaaatg attttagatg aatacaaaag tgcaaatagt tgattttagg tcatctaaat
    18661 gttaaacata aaattattag tactggtaaa tttataaaaa ctattccaaa aatctttttg
    18721 aatatttcaa aacacaataa attacttcaa atccctttga atatatttta cagcattata
    18781 gattgcttta aatctctttg aatattctac aagactatag attagtttaa atccctttga
    18841 atatatttta caacattata gattgtttta aatctctttg aatattctac aagactatag
    18901 attagtttaa atccctttga atatttcaaa acaccataga ttactttaaa tccctttgaa
    18961 tattctataa cactataaat tacttttaac ttttatataa ccataaagtt tttatctggc
    19021 actttaaatg gagttttata tcaaatttgc cttccatcga ataaccaaac ttaatttaat
    19081 tacacattcc aagagtcaaa tattcatt
//
LOCUS       DAEPKC010000078        18433 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.078, whole genome shotgun sequence.
ACCESSION   DAEPKC010000078 DAEPKC010000000
VERSION     DAEPKC010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18433)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18433)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18433
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.078"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(183..863)
                     /locus_tag="KR294_002722"
     CDS             complement(183..863)
                     /locus_tag="KR294_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0240787.1"
                     /translation="MQTKILIIDGDKDNCQKLKGFLEEKGISIDLAYNCEEAIGKIFS
                     NKYDLIFLEIILSDGDGWTLCKKIRNVTTCPIVYMTYINEDQSILNALNSGGDDYLIK
                     PLNLEILYAKVKAILRRMNSYVNNNENNTKLEEYNRTSGVIKLEDKIIKLTPTENKLL
                     NFFIENPEKTLTTKEIYEHVWMNEYLEDNYSVVVAVNGLRKKIEKDYKNPQKIITIRG
                     AGYYFNKE"
     gene            complement(913..2928)
                     /locus_tag="KR294_002723"
     CDS             complement(913..2928)
                     /locus_tag="KR294_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBH0240788.1"
                     /translation="MKKYNILKGTLIVLIVSLLAITGLNLLYKYDNKYTYKSIRASNG
                     ILTIDNDTFTKGKLVFLIDDWEFYNHKIFKPNDFTEQDIKPEYVFIGQYPDFSMRKGT
                     QSPYGNATYRMRIKNEGKDKLLSLELPEIFSASEVWINGEMVSKLGDVGTEKYRPKIK
                     NSVVSFIAKKNTEIIINVSNFSHYYSGLYYPPALGETKDISNMMFYRLLFYSIICFTT
                     FAIAIFSLSVWFLSNKSKIYLYFGCMCVFFAIHVSYPFVHLLGLPLVSFTYAVEDLSY
                     FMVVLCIICINGSISKIEENKVYRFLILPLGITMSIISIVIPIILLPYDMYFVNIYGK
                     LIDIYKYIVFIYILMSSLVSIYKKTCSEHISSYILVSVNTVFGISILFDAVTSNRFEP
                     IFTGWQTEYCGFVIVILFSVMMINRNRIIIKENEKLTRNLEHEVEVRTNELTTLLNER
                     KRFLADVAHDLKAPVSAIQAFIDLIKVGNIHVDEETRTYLYAINQKSNEVQNRVRSLQ
                     EFTSQDKSIGISEKICLNNFIKEIYENNLPDTQACGVNFETYVLEKKIYAKINKEMLT
                     RAFENLIYNALTFTPFDGKIILSMDKEDGFAIIKISDNGKGIPPENIPKVFDRFFTER
                     DNNEPKGQGLGLYIVKSIIREHGGEIFVDSELGKGTVFTIKLSLCFL"
     gene            complement(3000..3677)
                     /locus_tag="KR294_002724"
     CDS             complement(3000..3677)
                     /locus_tag="KR294_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0240789.1"
                     /translation="MYNLLVVDDDVDILNINQIYFSNIGFNVYTSETAKDAMDIVESI
                     VLDCIILDISLPDIDGYKMCNDIKEKVNIPIIFLSNYEHEEEKVRGFLAGGDDYITKP
                     YSLKELELRIYARMRQYKNITSVPNVLKFSALVINVNSRKVTFDGESIDLTTMEFEIL
                     LFLAENKEQVFSKIEIYNQVWKMPDIGDQHTVQVHIAQMRKKINSLSREHQYIQTVWG
                     KGYKFVP"
     regulatory      complement(4257..4340)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            complement(4573..5415)
                     /locus_tag="KR294_002725"
     CDS             complement(4573..5415)
                     /locus_tag="KR294_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBH0240790.1"
                     /translation="MFKKKIGVLLASTMLVGALAVGCSSNSGGSGDSGDSSKVSVSGS
                     TSIGPLMETIGEKFQEKNQGVSVEVQQIGSSGGIKNAIEGTSEIGMSSRDLKDEEKSA
                     GLKETKIAIDGIALITNTANSVKNLTMDQVKGIYTGKITNWKEVGGNDAPIVIVSREE
                     GSGTRDGFQEIVGFDSEELTKDAQISDGSGNIKTTVEGNENAIGYISFGYVDEKVNSL
                     KINDVEATDANVIANKYPISRPFILVNKEDGLSEKGKALIDYILSDEGQALVSEKGFI
                     KVNQ"
     gene            complement(5667..7451)
                     /gene="pepF"
                     /locus_tag="KR294_002726"
     CDS             complement(5667..7451)
                     /gene="pepF"
                     /locus_tag="KR294_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HBH0240791.1"
                     /translation="MGTDRSTIEEKYKWKIDKMYSSKEEIEKDISKVKNLIQEVKEYK
                     GKLSESKENLYKVLNISENASRIVQNLYVYTHMKQHEDTRINDNQGRATKTEMLSTDL
                     GVATSYIVPEILAIEENKLSEYLKDEKLSFYTKYIKDILRDKPHTLSEREEEILAATS
                     ELSTIPENVYDMLAYADMEFPEIEDEEGNKVKLSHSNYSLFIKSKNSRVRKDAFEGEF
                     STYEKYKNTFASTLYGGIKSEIFYAKTRKYNSAIEASLFSDDVSLDVYNNLISAIDKS
                     IPNLNKYVELKKKFLGLNEIHMYDLYVPLTDKFDMDIPYDKAQDIILEALKPLGEEYL
                     KVIKSAFDEGWIDVYDNEGKKGGAYSWGSYDSHPYILMSYKNDLNSLFTLVHELGHSV
                     HSHYSRTSQPFLYSDYKIFVAEVASTLNELLLINYLLENSKSKDETIYLLNYYLEQFR
                     TTVHRQTMFAEFEKIVHQRVESGEPLTADEFTNIYYKLNEKYYGKSAIVDKQIGIEWA
                     RIPHFYSNFYVYKYATGFSAASALSQQILSEGSTAVDRYINFLKSGGSEYPLEQLKSA
                     GVDMTKKESIEEALNVFAELVNKLEKEL"
     gene            complement(7517..8182)
                     /locus_tag="KR294_002727"
     CDS             complement(7517..8182)
                     /locus_tag="KR294_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HBH0240792.1"
                     /translation="MIDIGSKEIAIRLLLALIIGGIIGLEREKIRQFAGFRTHILIAI
                     GSCIVSITSIQLFFDYNLYTNADPARMPAQVLSGIGFLGAGAILKNKGGVKGLTTAAG
                     MWATACIGIAVGYGYYELAILGGLFVMIALFVLRIINTFLFSQEKNVLILKLSNLDSI
                     PFLYDKFEKNQLIVRNMEIECRNEEYWKVNFFVSYAKRIHLHDVMKEINMIEGVINVD
                     YLD"
     gene            complement(8333..8494)
                     /locus_tag="KR294_002728"
     CDS             complement(8333..8494)
                     /locus_tag="KR294_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartyl-phosphate phosphatase Spo0E family
                     protein"
                     /protein_id="HBH0240793.1"
                     /translation="MANNELEALKNEIEAVREEINTYIEYPEIFQEELVESSKKIDIL
                     INKYMYLSK"
     gene            complement(8572..9081)
                     /locus_tag="KR294_002729"
     CDS             complement(8572..9081)
                     /locus_tag="KR294_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HBH0240794.1"
                     /translation="MKTRKMTFLGLMIGYSLALYVLETYIPNPLIVIFPGAKLGLSNI
                     ITLISLMLLGVKDTVIIVTIRVILSSIFAGPLSYLLFSIGGAYLSLLFMYLASKIKDL
                     SLIGISIIGAIGHNIGQLIVASLIIENILAIGYLPFMLMASLVTGMFVGLVSRYTIPK
                     LKHFYSKFY"
     gene            9287..9505
                     /locus_tag="KR294_002730"
     CDS             9287..9505
                     /locus_tag="KR294_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HBH0240795.1"
                     /translation="MTVYDLKIGEKGFINSIDGDIKLSKRLLALGCINSTEIEVKKVA
                     PLGDPIIIRFRGFDLAIRKSDAKNISLQ"
     gene            9523..11469
                     /gene="feoB"
                     /locus_tag="KR294_002731"
     CDS             9523..11469
                     /gene="feoB"
                     /locus_tag="KR294_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HBH0240796.1"
                     /translation="MINVALLGNPNVGKTTVFNLLTGSNQYVGNWPGVTIEKKEGFLG
                     KEIKVVDLPGIYAMDTFSNEEKVSKSYLENEDVDVIVNVVDASNLSRNLYLTTQLMQF
                     NKPIVILLNMLDIAESKGVNIDAKKLSEELGVIVVPIIAKKKNGVDRIEEEIKGATQK
                     AFIYQKNFGSETETYKKLESILSRCTKTTYTQKKSISDKIDNIVLNPILAYPIFIGVL
                     FLLFKFTFDWVGGPLQEGFASLIEAYISAPVSDMLSNSSPWFKSLIVDGIIGGVGGTL
                     PFFPLIFTLFFGISLFEDSGYMSRTAFLMDKVMRKVGLSGKAFIPIVMGMGCSSPAIM
                     ATRTLESEKDRRVTALIAPLMTCGAKLPIYALFVAIFFPHNAALVTTSLYLVGIVMAI
                     VVALFLNKTAFKTEAEPFILELPEYRIPTIDALIKNTWNKSKGFLIRVVTVMFAMSVV
                     IWGLSSFNVFGYTEDINVSFLATLGHIISPIFKPLGFDDWRTSVAILSGLGAKEIVVN
                     SLNILYGNLTVVLPTIFNGVTAYTFLIFTALYTPCIAALATMKKEYGNKMMFTSFAYQ
                     FILAWIMAFIVKSIGGVLFMGNSIMEALIGGIIIVLALFILFNKFKSTKNGNVCSGCS
                     ICSGCPSANSCSSKEDSNKKNNAH"
     gene            complement(11648..12703)
                     /locus_tag="KR294_002732"
     CDS             complement(11648..12703)
                     /locus_tag="KR294_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBH0240797.1"
                     /translation="MTIQDYMLETPVRMREIISNADSLFNEVKRTNLKKIIITGSGTS
                     YHSGVQVQPYLQNLLDIDVVKMYPFMITEDTFKFDNENTLVVGVSQGGSSYSTYNAMK
                     LAEDKGCKIASMAGCKNALIDEISDYILTVNCGEEKSGAKTKGYYCTKLNLMLLGLQI
                     AREKGIISSEKYNEEINKILDAINRFEAVYKLSKQWIERNKEKLVNSKEIRIIGHSDI
                     YGDTLEAALKLLETMRIPVTGYEFEEFIHGIYNAINSDSTIFILDTGKEPRVTKMIDV
                     LSGWTENVFAIGRDVTENDKNLKIDITDNPYYQTFNFIVPIQLICGEIPTLRGVDPSV
                     PKDTRFHMKLGSKKLNK"
     gene            complement(12751..13551)
                     /locus_tag="KR294_002733"
     CDS             complement(12751..13551)
                     /locus_tag="KR294_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBH0240798.1"
                     /translation="MNKLTKKELRSMFWRSFALQGAFNYERMQNLGYCYSMLPAIKKL
                     YNKKENQAKAIERHLEIFNTTTVVVPAILGITAAMEEENANNPEFDESSISAVKTALM
                     GPLAGIGDSLFWGTFRIIAAGVGVSLAKEGNIFGPLLFLLLYNIPAFALRIFGLKYGY
                     QVGVNSLERIQREGLMEKIMSMATTVGLFVVGGMVATMLSITTPLKFNLNGAEVILQD
                     ILDKIIPNMLPLTFAFVIYYMLKRKVSVTKLTIGTIVTGIALHAIGLL"
     gene            complement(13544..14335)
                     /locus_tag="KR294_002734"
     CDS             complement(13544..14335)
                     /locus_tag="KR294_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH0240799.1"
                     /translation="MLVQATMLAIIAGVGILDGRIFGQSMLDRPIVTGMLVGLVLGDI
                     KSGIMIGAQLELIWMGIAGIGAATPPDVVTGGVLGTAFAILSGNGAEVALAVAVPVAV
                     LAQSLGVLVRIINSYFSQKAVFYAKQADFKKVTIMMWLPVILFFLSTSVPTFLAIMIG
                     ADKVTALINAIPKVILDGLGVAGTLLPAVGFALLMDMLLSKKMSVFFFIGFLLASYGG
                     LDITAIALFGVCVAFVLNFYINNKENNQNPQLAINTLTEGEIDFE"
     gene            complement(14375..14797)
                     /locus_tag="KR294_002735"
     CDS             complement(14375..14797)
                     /locus_tag="KR294_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HBH0240800.1"
                     /translation="MKKFLIATHGELSRELVDTSKLIIGSLTNIEYFCMTTDKSADDA
                     EKEIRSILSNNKDSEEFVVLTDVFGGSVANICTNLLLQGFKFELLTGVNLPMLLSILL
                     LVEEDTKLIVKSGLEEAKNGIVYVNELLENQNKIKNVM"
     gene            complement(14813..15292)
                     /locus_tag="KR294_002736"
     CDS             complement(14813..15292)
                     /locus_tag="KR294_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH0240801.1"
                     /translation="MVSLMRIDDRLIHGQVAYGWATSLGINVILVANDEAKNDQMKAM
                     SLNLAKPSNVTLYIRGVEESGEIVEKFASSKKSNVLVLVKNTKDALVVAKNSGGVLKE
                     INVGGLRYEEGKKKLTDLVAVDDDDINNFKQIGDLGIDIEFRMLPRDKKKQLSDLIK"
     gene            complement(15424..18180)
                     /locus_tag="KR294_002737"
     CDS             complement(15424..18180)
                     /locus_tag="KR294_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH0240802.1"
                     /translation="MRDEILSFVNECVLFNSFDELKKESGIITEDIVKKFNLSRTQSS
                     RLLNDLVKSDNLIKINSRPVIFLPKNKINDVVGPTKKSIYENLDELKNECKLLKQETV
                     FNSIIGYDNSLKEVIEQIKTAVLYPNGGLTIMLTGESGVGKTFLAKIIYKYSVSSNVL
                     EKNSPYNVLNCAQYYNNLELLSSLLFGHVKGAYTGANESRAGLIEQSDGGVLFLDEVH
                     RLNSEGQEKLFTFMDTGTFSRIGENGVIRKARVRLIFATTESLSEFLQTFLRRIPINI
                     YVPNIEERGTIEKRKIVEHFIYEESKVLGLPIEITQITLNAILKIKFKGNIGECKNVI
                     KYACGRAYAKNQRRNGNIFVTLQDLPRNLYIENVDIFQFQSGKSKSIIFSPKQFSIEM
                     SNGRNKRNIIYQSFIKCLDYFDRLEKNEITKEKFSKKSSNLMIRLMDNLVFSNNDENN
                     NVLMELIISIMQDIFRNLEVNNNIKYDGNNVLAFSSYLYLKDESYQLSDEYKALENKL
                     LIYLKKESYKEYSIISKISTLITNRLDMYLNNVDTIIMIIFIKSTIIRMKFNQVNATI
                     IAHGYATASSMANVCNRMLGKNIFTAIDMPIDATIADVSKQMSRYLEGDRIKNGLIVL
                     FDMGSLNLIYEDLKNKINSPMLFIDQISTISALEVGNLLMQGKNIEEIAEIMDEETKP
                     NIQLYYPQKNKEYAIISSCFTGIGIAIKIQHLLSESLIGIVDVKIIPYDYDSLVSMGD
                     KEPVFEMYDVMAIVGTANPNVNGVDFILLEDIISGKGEDDVFRIFSRVVENEKIKNIN
                     DSIVKNFSLIRVIDSLTILDSKKIIERIEEGINAIENIQKKKLSNDKKISLYVHLSCM
                     IERLVRQTEIEEYTDMDLLIKNHHSEVKLIKNAFSVLEKSYSVQIPISEIGYIYNIIY
                     GLPQ"
BASE COUNT         6037 a         3152 c         2029 g         7215 t
ORIGIN      
        1 tataaaataa tagttccatt acgcattttt ttatataata aaactgactg taatttaact
       61 ggcaaagtct agaagaatag gatttatcaa ttaaattaca gtcagctatt ttataataat
      121 ttagtttaga tatcgttagt atttcacatt tataacaatt attaatgata ttaatatatt
      181 tattattcct tattaaaata atatcctgct cctcttattg ttataatttt ctgaggattt
      241 ttataatctt tctctatttt ctttcttaat ccattcactg caactaccac actatagtta
      301 tcctctaagt attcattcat ccatacatgt tcatatatct ctttagtagt caaagtcttt
      361 tcaggattct ctataaaaaa gtttaacaac ttattttctg ttggagtcaa ttttattatt
      421 ttatcttcta actttattac tccactagtt ctattatatt cctctaattt tgtattattt
      481 tcattattat ttacatatga gttcattctt cttaaaatag cttttacttt tgcgtataat
      541 atttctaaat ttagaggctt tattaagtaa tcgtctccac cagaatttaa agcatttaaa
      601 atgctttggt cttcatttat ataagtcata taaacaattg gacaagtagt tacatttcta
      661 atttttttac aaagagtcca tccatcacca tcacttagaa ttatttctaa aaatattaaa
      721 tcatatttat tgctaaatat ttttccaata gcttcttcac aattatatgc taaatctata
      781 cttattcctt tttcctccag aaatcctttt agcttctggc aattatcctt gtctccatct
      841 attatcaata tcttagtttg cattataatc actcccaaat atcattattc ttttatatta
      901 aataagctat tattataaaa aacatagact taattttatt gtaaaaacag ttccttttcc
      961 tagttctgaa tctacaaata tttctccacc atgctctctt ataatggatt tgacaatata
     1021 tagccctaac ccttgccctt ttggctcatt attgtctctt tctgtaaaga atctgtcaaa
     1081 tacctttggt atattttctg gaggtatacc ttttccatta tcagaaattt taataattgc
     1141 aaatccatct tctttatcca ttgataaaat tatctttcca tcaaatggag taaaggtcaa
     1201 agcattataa attaaattct caaatgctct tgtaagcatc tctttattta tctttgcata
     1261 tatttttttc tccaatacat aagtttcaaa gtttacacca catgcttgtg tatctggcaa
     1321 attattttca tatatctctt taataaaatt attcagacat attttttcac taataccaat
     1381 gcttttatct tgtgatgtaa attcttgcaa actacgtact ctattttgta cttcatttga
     1441 cttttgattt atagcataaa gataggttct tgtctcttca tctacatgaa tattaccaac
     1501 ctttatcaaa tctataaatg cttgtatagc cgaaacaggt gcctttaaat catgtgctac
     1561 atctgccaag aatcttttac gttcatttaa caatgttgta agttcattag ttctcacttc
     1621 aacttcatgt tcaagattcc ttgtaagttt ttcattctct tttattatta ttctattcct
     1681 gtttatcatc ataacagaaa ataaaataac aattacaaac ccacaatatt ctgtttgcca
     1741 ccctgtaaat ataggctcaa atctattact cgtaactgca tcaaataata tgctaattcc
     1801 aaaaacagtg tttactgaaa ctaaaatata agaacttata tgctcagagc atgtcttttt
     1861 atatattgaa accagcgaag acattaatat atatataaat acaatatatt tatatatgtc
     1921 tattaacttc ccatatatgt tgacaaagta catatcatat ggaagaagaa taattggtat
     1981 cactatagat atgatactca ttgtaattcc taatggtaaa attaaaaatc tatacacttt
     2041 attttcttct attttggata tacttccatt tatacaaata atacataaaa ctaccataaa
     2101 atatgacaaa tcttcaaccg catatgtaaa gcttaccaaa ggcagtccta acaaatgtac
     2161 aaagggatag gatacatgga tggcaaagaa aacacacata catccaaaat ataagtaaat
     2221 tttacttttg tttgaaagaa accatacaga caatgaaaat atagctattg caaaagttgt
     2281 gaagcaaatt atactataaa aaagtaatcg ataaaacatc atattactta tgtcctttgt
     2341 ttctcctaat gcaggcggat aatacaaacc actataataa tgtgaaaaat tcgatacatt
     2401 gattataatt tctgtatttt tctttgcaat aaaacttact actgaatttt taattttggg
     2461 tctatatttt tctgttccta catctcctaa tttagaaacc atttctccat ttatccatac
     2521 ttcacttgcg gaaaaaatct caggaagctc taaacttagt agcttatcct tgccttcatt
     2581 ttttattctc atacgataag tagcattccc atatggtgac tgagtccctt ttctcataga
     2641 aaaatctgga tattgaccta taaaaacata ttctggtttt atatcttgct ctgtaaaatc
     2701 attcggttta aatattttat gattataaaa ctcccagtca tctatcaaaa agacaagttt
     2761 acctttagtg aaagtatcat tatctatagt taaaattcca ttacttgctc taatagactt
     2821 atatgtatat ttattatcat atttatacag aagatttaat cctgttattg ccagcagaga
     2881 gactatcaat acaatgagag ttccttttag tatattatac tttttcattg tatcaaccac
     2941 atctctttca tagtagtatt aaataaaaca agaactattt attaattaca gtatctcact
     3001 tatggtacaa acttatatcc ttttccccat acggtttgaa tgtattgatg ctccctgctt
     3061 aaagaattaa ttttttttct catctgtgca atatgaacct gcactgtatg ttgatctcca
     3121 atatcaggca ttttccaaac ttggttatat atctctatct ttgaaaatac ttgttctttg
     3181 ttctcagcta gaaacaataa tatttcaaat tccatagtag ttaaatctat actttctcca
     3241 tcaaaagtta cttttcttga atttacattt attactaacg ctgaaaactt taacacatta
     3301 ggaactgatg taatattttt gtactgcctc atacgagcat atattctaag ttcaagttct
     3361 tttaaactat aaggttttgt tatataatca tcccccccag ctaaaaatcc ccgaactttt
     3421 tcttcttcat gctcataatt agataaaaat attataggta tgttaacctt ttcttttata
     3481 tcattgcaca ttttatatcc atctatatct ggcaatgaaa tatccaaaat tatacagtct
     3541 aaaactatac tctctactat atccatagca tctttagcag tctctgatgt atatacatta
     3601 aaacctatat tagaaaaata aatttgattt atgtttaaaa tatcaacatc atcatctaca
     3661 accagtaaat tatacattac accactccat tcaaaggtat tttaattata attccaagtt
     3721 ttatagttat tacaaattat aatgttttat tttcatatat aactggtatt attattttat
     3781 aatatcttta caaactagac tataatactt aagtattttt gaataattct tgaatattgt
     3841 attaaacatt aagattcatt attaaatact aattaaagtc tccgattgtt ggagaatgga
     3901 gcttaaagtc attttcacgt ataaatttat tatttttcta gaaacttgtc tattggctag
     3961 tttgagtatt gatttatatg atttatatgg ttataatata aaataaattg tattattttg
     4021 gtaaatatat tgttacaaaa ggtttatatt ctgcatctca atgtttataa aaactttatt
     4081 ttcttattat aatactatta ttcttttaaa aaaatttccc ttttccaaca aatggctact
     4141 ttaaaagcca aaattttacc tatcaataaa aatcttaacg actaatactc ttattttcaa
     4201 attttgcaac atttttgtta attttaaaac aaaaaaagac tatgcaatat aaaaattata
     4261 ttcatagccg gttgcaccac taactccata tatctctaga tgcccaataa taagatatac
     4321 ttctcagttt ctaaaatatt tttattaaaa atcttttata tattttcata aatttctttt
     4381 ttattctaac attgtaatat tattttgtca atatttccat attcttagag ataagatact
     4441 aaaataccta ttttatctaa agatatttat atttctacat tcaataatag acaataccct
     4501 gcaagttaaa gcatcatttt tatgagctta tctcacaggg tattatatgt ttactttata
     4561 ttataactct tgttattgat taactttaat aaatcctttt tctgaaacaa gtgcttgtcc
     4621 ttcatcactt aatatataat ctattaaagc tttacctttt tctgacaaac catcttcttt
     4681 attaactaat ataaatggtc ttgatattgg atatttatta gctattacat ttgcatcagt
     4741 tgcttcaaca tcatttattt ttaaactatt tactttctca tcaacatatc caaatgatat
     4801 atatcctata gcattttcat ttccttcaac tgtagttttt atatttcctg aaccatcact
     4861 tatttgtgca tctttagtta gttcttctga atcaaaccct acaatttctt ggaatccatc
     4921 tctagttcct gaaccttctt ctcttgatac tattactatt ggtgcatcat ttcctcctac
     4981 ttctttccag ttagtaatct ttcctgtata tataccttta acttggtcca ttgtcagatt
     5041 ttttactgag tttgcagtat tagttatcaa tgctatacca tctattgcta ttttagtttc
     5101 ctttaatcca gcactttttt cttcatcttt taaatctctt gaactcattc ctatttcaga
     5161 tgttccttct atagcatttt ttatacctcc agaagaacca atctgttgta cttctacact
     5221 aacaccttga tttttttctt gaaacttttc tccgatagtt tccataagag gacctattga
     5281 agttgaacct gaaacagaaa ctttgcttga atctcctgaa tcacctgaac ctcctgagtt
     5341 agaactacat cctactgcta aagctccaac taacattgta ctagctaaaa gaacgcctat
     5401 tttcttttta aacattttac ttacccccgc ttatatttta attttttgtt gtcatttttc
     5461 tatattttaa taatacagat tctttgttaa atgaatatta gagcagggtt aagtaaatgt
     5521 aaatattgtt aaatacatgt aaaaacttaa ttttatatga tttattctta attagattaa
     5581 ctttttaaag ttactttagg cagatataaa cataatacaa ctcatattat cagaagtctt
     5641 cattgaagct atcaacctat cacatcctat aattcttttt ctagtttatt aactaattca
     5701 gcaaatacat ttaaggcttc ctctatagat tcttttttcg tcatatctac accagcagat
     5761 tttaattgtt ctagtgggta ttctgaccct ccacttttta agaagtttat atatctatct
     5821 actgcagtac ttccttctga aagtatctgt tgacttaaag cacttgcagc agaaaaccct
     5881 gtggcatact tatatacata gaagtttgaa taaaaatgag gtattctcgc ccattctatt
     5941 cctatttgtt tatctactat tgcagatttt ccgtaatact tttcatttaa tttgtagtat
     6001 atattagtaa attcatcagc agtaagtggt tctccactct ctaccctttg atgtacaatt
     6061 ttttcaaatt cagcaaacat agtttgtcta tgaactgtag ttctaaattg ttctaaataa
     6121 taatttaata agtatatagt ttcatcctta gacttagaat tttctaataa ataatttata
     6181 agaagtaatt catttaatgt agatgcaact tctgcaacga atatcttata gtccgaatat
     6241 aaaaatggtt gacttgttct tgaataatga ctgtgaacag agtgccctaa ttcatgaact
     6301 aaagtgaata gagaattaag gtcattttta tagctcatta atatataagg atgtgaatca
     6361 taacttcccc aagaataagc tcctcctttt ttaccttcat tatcatatac atcaatccac
     6421 ccttcatcaa aagcactttt tatgaccttc aagtattctt ctcctaaagg tttaagtgcc
     6481 tctaatatga tatcctgtgc tttatcatat ggtatatcca tgtcaaattt atctgtcaaa
     6541 ggaacataca aatcatacat gtgtatttca ttcaatccta aaaatttctt tttaagctca
     6601 acatatttat ttagattagg aatactttta tctatagctg atataagatt attgtaaaca
     6661 tctaaactta catcatctga aaataaagac gcttctattg ctgaattata ctttctagtt
     6721 tttgcgtaaa atatctctga ttttattcca ccataaagcg ttgaggcaaa tgtattttta
     6781 tatttctcat atgttgaaaa ttcaccttca aaagcgtctt ttctaactct actattctta
     6841 ctttttataa ataaagagta gtttgaatga gaaagcttaa ccttattccc ctcctcatct
     6901 tctatctcag gaaattccat atctgcatat gctaacatat cgtatacatt ttctggaatt
     6961 gtcgataatt ctgatgtagc tgcaagtatt tcttcctctc gttcactcaa agtatgtggt
     7021 ttatctctca atatatcctt tatatatttt gtataaaagg atagcttctc atcttttaag
     7081 tattcactta acttattctc ttctatcgcc agtatttctg gaactatata agaagtagcc
     7141 acacctaaat cagtagataa catttctgtc ttagtggctc ttccttgatt atcattaatt
     7201 ctagtatctt catgttgttt catatgagta tatacatata aattttgaac aatcctagat
     7261 gcattttcag agatatttaa tactttatat aagttctcct tactctcaga aagcttccct
     7321 ttatattctt ttacttcttg gataagattt tttactttac ttatgtcttt ttcaatttcc
     7381 tctttactgg agtacatctt atctatcttc catttgtact tttcttctat tgtacttcta
     7441 tcagttccca tatcatacac ctctatttta atttgtttta tattttattc actttacaaa
     7501 atatattgta tatattttag tccaaataat ctacatttat tactccttct atcatattta
     7561 tttctttcat aacatcgtgt aagtgtattc tcttagcata agatacaaaa aaattaacct
     7621 tccagtattc ttcattacga cattctattt ccatatttct tacgataagt tgattttttt
     7681 caaatttatc atataaaaaa ggtatagagt ccaaattgct taattttaat atcaatacat
     7741 tcttttcttg gctaaataaa aacgtattga ttatcctaag cacaaataat gctatcatta
     7801 caaataatcc acctagaatt gccaattcat aataaccata tccaactgct ataccaatac
     7861 atgcagttgc ccacatccca gcagctgtag taagcccttt taccccacct ttatttttta
     7921 aaattgctcc tgcacctaaa aaaccaattc cagataatac ttgagcaggc attcttgctg
     7981 ggtcagcatt tgtatacaaa ttataatcaa agaataattg aatcgaagtt attgaaacaa
     8041 tacaagaacc tattgcaatt agtatatgtg tcctaaatcc tgcaaactgt cttatttttt
     8101 ctctctctaa gcctattatt cctcctatta ttagtgctaa tagtaacctt attgctatct
     8161 ccttacttcc tatatcaatc ataatataaa accctcctga cttaattaca acttatgtcc
     8221 tacagataat ttacacatca gaaatactat tttatatctt aatattatta ttaatatatg
     8281 taaaatatag ccatctgtta atttttgata caaaaaaacc cacaactgtg ggctatttgc
     8341 ttaggtacat gtatttattt attaatatat ctattttctt acttgattct actaactctt
     8401 cttgaaatat ttctggatat tctatgtatg tatttatctc ttccctaact gcttcaatct
     8461 cattttttaa cgcttctaat tcattgttcg ccataataat caccactatt acaaatttgt
     8521 atatttttat atacatttta tcaaacaata ttatattttg tcaatattat gtcaataaaa
     8581 cttactataa aaatgcttta atttaggtat tgtatacctg gatactaagc ctacaaacat
     8641 accagttact aatgatgcca ttaacataaa tggtaagtac cctatagcaa gtatattttc
     8701 tatgattaaa cttgcaacta ttaattgacc tatattatgc cctattgcac ctataatgct
     8761 tatccctatt agtgataaat cttttatttt actcgctaaa tacataaata aaagactcag
     8821 ataagctcct cctatactaa atagtagata tgataaaggg cctgcaaata ttgatgacaa
     8881 aattaccctg atagtaacaa ttataacagt atctttgaca cctaacaaca ttaatgaaat
     8941 taaagttata atattgctca aacccaattt tgcccctgga aatataacta taagaggatt
     9001 tggtatatat gtctctaata catataaagc taaactatac cctatcataa gacctaaaaa
     9061 tgtcattttt ctagttttca ttaagttaac tcctccaaat tttatctatc atcttacatt
     9121 ataatacaaa atatataaaa acacctaatt tagactaaaa tatttttaat ctatttagaa
     9181 taaatattag ttatttcaat gtgcaattac ctctataaat cttgactttt tgtatcatac
     9241 ttgttacaat tttaatgata atgaatttca ttaggaggtg ttaataatga ctgtttacga
     9301 tttaaaaata ggagaaaaag gatttattaa tagtatagat ggagatatta aattatctaa
     9361 aagattgctt gcacttggat gtataaatag tactgaaata gaagttaaaa aggttgcccc
     9421 acttggagac ccaattataa ttagatttag aggctttgac cttgcgatta gaaaatctga
     9481 tgctaaaaat atttctttac aataatagag gaggagctac ccgtgattaa tgtagcatta
     9541 ttaggaaacc caaatgtcgg taaaactact gtttttaatc tacttacagg ttcaaatcaa
     9601 tatgtaggta actggcctgg tgttactata gaaaaaaaag aaggatttct tggaaaagag
     9661 ataaaggttg tcgatttacc tggtatatat gcaatggata ctttctcaaa tgaagaaaag
     9721 gtttctaaat catatttaga aaatgaagat gttgatgtaa tagtaaatgt agttgatgct
     9781 tctaatttat caagaaacct ttacttaaca actcaactta tgcaatttaa caagcctata
     9841 gttatattgc ttaatatgtt agacattgca gaatctaaag gagttaatat agatgccaaa
     9901 aaattaagtg aagaacttgg agtaattgtt gttccaatta tagcaaaaaa gaaaaatggt
     9961 gttgatagga tagaagaaga gattaaggga gctacgcaaa aagcttttat atatcagaaa
    10021 aactttggaa gtgaaacaga aacatataaa aaattagaat ccattttatc gagatgtaca
    10081 aaaactacat atacacaaaa gaaatctatc agtgataaga tagacaatat agtcttgaat
    10141 cctatattag catatccgat atttattggt gtattgttcc tcttatttaa atttaccttt
    10201 gactgggtcg gaggaccact acaagaggga tttgctagtc ttatagaggc ttatatttct
    10261 gcacctgtta gtgatatgtt atctaactct agcccatggt ttaaatcact tatagttgat
    10321 ggaataattg gaggtgttgg tggtacttta ccattcttcc ctttaatatt tacattattc
    10381 tttggtatat cgttgtttga agatagtgga tacatgtcaa gaacagcatt tttaatggat
    10441 aaagttatga gaaaggttgg tctatctggt aaagctttta tacctatagt tatgggtatg
    10501 ggatgttctt ctccagctat aatggcaact agaacattgg aaagcgaaaa agatagaaga
    10561 gttacagctc ttattgcacc acttatgact tgtggagcaa agctacctat atatgcacta
    10621 tttgtagcta tattctttcc acataatgct gctttagtaa ctacatcact gtatttggtg
    10681 ggtatagtta tggcaattgt agttgcatta ttcttaaata aaacagcctt taaaacagag
    10741 gctgaaccat ttatattaga attaccagaa tatagaatcc ctactataga tgcacttatt
    10801 aaaaatactt ggaataaatc aaaaggtttc ttgataagag ttgttactgt catgtttgca
    10861 atgtcagtcg taatttgggg actttcttca ttcaatgttt ttggatatac agaagatata
    10921 aatgtaagct tcttggctac tctaggtcat attatatctc ctatattcaa acctcttggt
    10981 tttgatgatt ggagaacttc agttgctatt ttaagtggtc ttggagcaaa agaaatcgta
    11041 gtaaactctt taaatatact atatggtaat ctaactgttg tcttaccaac aatatttaat
    11101 ggagttactg catatacatt cttgatattt actgctttat atactccatg tatagctgca
    11161 cttgcaacta tgaaaaaaga atatggcaat aaaatgatgt ttacatcatt tgcatatcaa
    11221 tttatactag catggataat ggcttttata gttaaaagta taggtggagt actatttatg
    11281 ggtaattcaa taatggaagc tttgataggt ggaataatta tagtccttgc actctttatt
    11341 ctgtttaata aattcaagtc tacaaaaaac ggaaatgtct gtagtggatg ttctatttgt
    11401 tctggatgtc caagtgctaa ttcttgctca agtaaggaag acagcaataa aaaaaataat
    11461 gcacactaat atataaatat tttagtttaa aataagataa aagtgggtgt ctcaaaatta
    11521 actttttagt tcatgaggca ctctttttta tataaaatca aatatatttt catcatttca
    11581 acagtaaaaa agagcttatc tagtaaaaaa gaggcttatc tctattttga gacaacctct
    11641 ttttttgtta cttattcagt ttcttgctac ctaacttcat gtggaaccta gtatcttttg
    11701 gaacacttgg gtctacacct cttaatgtag gtatttcccc acatattagt tgtataggta
    11761 ctataaaatt aaatgtttga tagtaaggat tatctgtgat atcaatcttt aaatttttat
    11821 cattttctgt aacatctcta cctatagcaa atacattttc cgtccaacca gaaagtacat
    11881 caatcatctt agttactcta ggttcttttc ctgtatctag tataaatata gtagaatcac
    11941 tatttatagc attatatata ccatgtataa actcttcaaa ctcataccca gttacaggta
    12001 ttctcattgt ttccaataat tttaatgctg cttctaatgt atctccatat atatcagagt
    12061 gacctattat tcttatttct ttagaattaa ctaacttttc tttgtttctt tcaatccatt
    12121 gtttagagag cttatacact gcttcaaatc tattaattgc gtctaatatc ttatttattt
    12181 cctcattgta cttttcacta gatattatac ctttttctct agctatttga agacctaata
    12241 acattaagtt taactttgta caataatatc cttttgtttt agctccagat ttttcttcac
    12301 cacaatttac tgttaatata taatcagaaa tctcatctat taaagcattc ttacaacctg
    12361 ccatagatgc tattttacag cccttatctt cagctaactt catagcgttg tatgtagaat
    12421 aactactccc accttgagat acacctacta ctagggtatt ttcattatca aacttgaatg
    12481 tatcttcagt tatcataaat ggatacattt tcacaacatc tatatctaat aaattttgta
    12541 aatatggttg cacctgcact cctgagtgat agctagtacc tgaacctgtt attataatct
    12601 tttttagatt tgttctctta acttcattaa ataagctatc tgcattagat ataatttctc
    12661 tcattctaac tggtgtttct aacatataat cttgtattgt cattttatac accttcctta
    12721 tctatatatt caataaatta taattaattt ctataacaaa cctatagcat gtaaagcgat
    12781 tcctgttact atagtgccta tagttaattt tgttacactt acctttctct ttaacatgta
    12841 gtatattaca aatgcaaagg ttaaaggtaa catattaggt attattttat ctagtatatc
    12901 ttgtaaaatt acttctgcac catttaagtt gaatttcaga ggagtagtta tactcaacat
    12961 agttgcaacc attcctccta caacgaataa accaacagtt gtagccatag acattatttt
    13021 ctccataagt ccctctcttt gtattctttc aagagaattt acccctactt gataaccata
    13081 cttaagtcca aatattctaa gggcaaatgc tggtatattg tataatagta agaataatag
    13141 tggtccaaag atattacctt cttttgcaag tgatactcct actcctgctg ctataatcct
    13201 aaatgttccc cagaataatg aatcaccaat tcctgcaaga ggtcccataa gagctgtttt
    13261 aacagcacta attgaacttt catcaaattc tggattatta gcattctctt cttccatagc
    13321 ggctgttata cctaatatag caggaactac cactgtcgtt gtattaaaaa tctccaaatg
    13381 cctttctatt gcttttgctt gattttcttt cttattgtat agcttcttta ttgcaggtaa
    13441 cattgaataa cagtaaccta agttttgcat tctttcgtaa ttaaatgcac cttgaagagc
    13501 aaatgaacgc caaaacatac ttcttaattc tttttttgtt aatttattca aagtcaatct
    13561 ctccttccgt taaagtattg attgctaatt gaggattttg attattttct ttgttattga
    13621 tataaaagtt tagtacaaat gctacacata ctccaaataa agctatagca gttatatcta
    13681 atccaccata agatgctaac aaaaacccta taaagaaaaa tacagacatc ttttttgaaa
    13741 gtaacatatc cataagcaat gcaaaaccta ctgctggcaa caatgttcct gcaacaccca
    13801 atccgtctaa tataacttta ggtattgcat ttattaatgc tgtaacttta tcagcaccaa
    13861 tcataattgc taaaaaggtt ggaactgatg tacttaaaaa gaataatatt actggcaacc
    13921 acatcattat ggtaactttc ttaaaatcag cctgtttagc atagaaaact gccttttgag
    13981 aaaagtacga atttattatt ctaactaata ctccaagaga ttgtgctaag actgctactg
    14041 gtactgctac tgctaaagca acttctgcac cattacctga taatatagca aaagctgtac
    14101 ctaatacacc tcctgttact acatctggag gagtagctgc acctattcct gcaattccca
    14161 tccaaattaa ttcaagctgt gcaccaatca taattcctga ttttatgtct cctaaaacta
    14221 atcctactaa catacctgta actattggcc tatcaagcat agattgacca aatatacgcc
    14281 catctagtat accaactcct gctataatag ctaacatagt agcttgtact aacatattga
    14341 acctccattt taacttagtt taatttacat taaattacat tacatttttg attttgtttt
    14401 gattttctaa taactcattt acataaacaa ttccattttt tgcttcctct aatcctgatt
    14461 taactattag ttttgtatcc tcctcaacta ataaaagtat agataaaagc attggtaaat
    14521 ttactcctgt caataattca aatttgaacc cttgtaaaag taagtttgta catatgtttg
    14581 ccacacttcc accaaacaca tctgttaaga caacaaattc ttcactatct ttattatttg
    14641 ataatatact tctaatttct ttctcagcat catctgctga tttatccgtt gtcatacaaa
    14701 aatactcaat attagttaat gaaccaatta ttaatttact tgtgtcaaca agctctctgg
    14761 acaattctcc atgtgttgca attagaaatt ttttcattct ctttctccta aattatttta
    14821 ttaaatctga tagttgtttc tttttgtctc taggtaacat tctaaattct atatcaatcc
    14881 ctaaatcacc tatttgttta aagttattta tatcatcatc atcaacagca actaaatctg
    14941 taagtttctt cttcccttcc tcatatctta atcctcctac atttatttct tttaatactc
    15001 ctcctgaatt tttagctaca actaaagcat ctttggtatt ttttactaac actaatacat
    15061 tgcttttctt tgaagaagca aatttttcta ctatttctcc agattcctct acccccctta
    15121 tatataaagt tacattgcta ggtttcgcta agttcagtga catagctttc atttggtcat
    15181 tttttgcttc atcatttgca actagtatta catttatacc tagtgatgtt gcccatccat
    15241 atgcaacctg accatgtatc aatctgtcat caattctcat caaagatacc attttcccca
    15301 aatcctccat catacattaa aatttttatt gtttatactc tcatttatct ataaaagcaa
    15361 aaagtatgcc aaatactggc atactttttt aaatttcatt cacttatttt gtaatcttgt
    15421 attttactgt ggtagaccat agataatatt ataaatatat cctatctctg aaattggtat
    15481 ttgcacacta taactctttt ctagcacact aaatgcattt tttattagtt ttacttcact
    15541 atgatggttt ttgattaaca aatccatatc agtatactct tcaatttcag tttgtctaac
    15601 taatctttca atcatacaac ttaagtgaac atataaagaa atctttttat catttgaaag
    15661 ttttttcttt tgaatatttt ctatagcatt aattccttct tctattctct ctattatctt
    15721 ttttgaatct aaaatagtta gactatctat tactctaatt aatgaaaaat tctttacaat
    15781 agaatcattt atgttcttta ttttttcatt ttctactact ctgctaaata ttctaaaaac
    15841 atcatcttct ccttttcctg atattatatc ctctaataat ataaaatcta ccccattcac
    15901 atttggattg gcagttccta ctatagccat cacatcatac atttcaaaaa ctggttcttt
    15961 atctcccata gaaacaagac tatcataatc ataaggtatt attttgacat caactattcc
    16021 aattaaactt tcggaaagta gatgttggat ttttatagca atacctatcc ctgtaaaaca
    16081 agatgatatt atagcatatt ctttattttt ttgaggataa tacaattgta tattaggttt
    16141 agtttcttca tccataattt ctgcaatctc ttcaatgttt ttaccttgca ttaataaatt
    16201 tcctacttct agtgcagaaa tagtggatat ttggtctata aataacattg ggctatttat
    16261 cttattcttt aaatcttcat atataagatt aagagagccc atatcaaata atacaattaa
    16321 accattcttt atcctatctc cctctagata tctagacatt tgttttgata catcagcaat
    16381 agtagcatct ataggcatat caatagctgt aaatatattt ttacccaaca tccgattaca
    16441 tacattcgcc atactactgg cagtagcata tccatgtgct ataatagtcg cattaacttg
    16501 attaaatttc attcttataa ttgttgattt aataaatata atcattatga ttgtatctac
    16561 attattaaga tacatatcca atctattcgt tattaatgtt gatattttac ttattataga
    16621 gtattctttg taactctctt tttttaaata tattagtaat ttattttcta aagctttata
    16681 ctcatcagac aattgataag attcgtcctt caaataaaga taagacgaaa atgccaatac
    16741 attattccca tcatatttta tattgttatt aacttctaaa tttctaaata tatcctgcat
    16801 tatcgatatt ataagctcca taagtacgtt attattttca tcattatttg aaaagactaa
    16861 attgtccatt agtctaatca ttagattaga actcttttta ctaaattttt cctttgttat
    16921 ttcatttttt tctagtctat caaagtaatc taaacatttt atgaaacttt gatagattat
    16981 atttctttta tttcttccat ttgacatttc aatactaaat tgtttaggag aaaagataat
    17041 gcttttgctt ttaccacttt ggaattgaaa tatatctaca ttttctatat aaagatttct
    17101 aggaaggtct tgaagagtaa caaaaatatt tccatttctt ctttgatttt ttgcataagc
    17161 tcgtccacat gcatatttta ttacattttt acattcacct atattcccct tgaattttat
    17221 ctttaaaatc gcatttaatg taatttgagt tatctctata ggcaaaccaa gtaccttact
    17281 ttcttcataa ataaaatgtt ctacaatctt tcttttttca atagtccctc tttcttctat
    17341 attgggaaca taaatattta tgggtattct tcttaaaaag gtttgtaaaa attcagatag
    17401 actttctgtt gtagcaaata ttaatcttac cctagctttt ctaattactc cattctctcc
    17461 aatcctagaa aacgtacctg tatccataaa tgtaaataac ttttcctgac cttcactatt
    17521 taatctatgg acttcatcta aaaataaaac accaccatct gattgttcta ttagacctgc
    17581 tctagattca tttgctccag tatatgctcc ttttacatgc ccaaataata gactagacaa
    17641 taactccaaa ttattataat actgcgcaca gtttaacaca ttgtatggag aatttttttc
    17701 taatacatta ctgcttacac tatatttgta tattatcttg gctaaaaaag tttttcctac
    17761 tccactttca cctgtcagca ttattgtaag tccgccattt ggataaagta cagcggtttt
    17821 tatttgttcg attacttctt ttaagctatt atcatatcct atgatactat taaacacagt
    17881 ctcttgcttt aataatttac actcattttt aagttcatct aaattttcat aaatactttt
    17941 ttttgtaggt cctactacat catttatttt atttttaggt aaaaaaataa caggtctact
    18001 gtttatcttt ataagattat cagattttac taaatcattt aataatctac ttgattgagt
    18061 tctacttaaa ttaaactttt ttactatatc ttctgttatt atgccacttt cttttttaag
    18121 ttcatcaaag ctgttaaata atacacattc atttacaaaa cttaaaattt catccctcat
    18181 gttcaacctc caatacaaat atcaataata ctataatatt agtatatcat ttatatattt
    18241 atgaaaaaga taattatatt cctatcttga ttctcttttg taaggttgta aaatcaaact
    18301 ttttataagt ataaaatcta gattttttaa cataatctca aggttcttat ctttccatat
    18361 atctgacata gaatttatat aagaatatat ttattgtatt tattataata aaaagtaaaa
    18421 cattataggt att
//
LOCUS       DAEPKC010000079        18276 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.079, whole genome shotgun sequence.
ACCESSION   DAEPKC010000079 DAEPKC010000000
VERSION     DAEPKC010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18276)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18276)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18276
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.079"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..612
                     /locus_tag="KR294_002738"
     CDS             <1..612
                     /locus_tag="KR294_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBH0240803.1"
                     /translation="LSIITDRLSSIEDSLDIKNQVAKINFLVNSILYSSRSNTMFEDV
                     FINKFNLEKLVKMSIKNNSFLLIKNNVEVSLNELENDVYTDSKCMSYVLDQIINNAIK
                     YSKEVGKIEFNSKKLENGVVLSIKDFGIGINEEDISRVFDKGFTGKNGRNQLYKSTGM
                     GMYFVKKMIDSLGHEIEVCSKIGSYTIFNIYFYDISDYLSIDS"
     gene            1043..2203
                     /locus_tag="KR294_002739"
     CDS             1043..2203
                     /locus_tag="KR294_002739"
                     /EC_number="2.7.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anhydro-N-acetylmuramic acid kinase"
                     /protein_id="HBH0240804.1"
                     /translation="MITMYSVGLMSGTSLDGVDAVLAEISGNGRNTKVKQIEFITLEI
                     PKDIKDEIRKCCIEEESSVDLICSLNFKLGYLFSKAVKSVCHKANFHIANLDFIASHG
                     QTIFHIPRSYNNFVSSTLQIGEPAVIAYETNTKVISNFRVMDIAAGGEGAPLVPYSEF
                     LLYSDNNKNLALQNIGGIGNITIIPKSCNIDDVFAFDTGPGNMIIDGVCQRLFNRKYD
                     KNGYFASKGKINEEMLKDLMSHKYLSQAPPKSTGREVFGQVYLDNMLNKYKHVDKYDL
                     IATVTMFTAKAIYYNYKNFILPKVNVDTLLIGGGGAHNLTLIGYIKELLLEVEVLTQD
                     EYGYSSDAKEALAFVILGNETLNNSFSNVISATGAKNKVILGNITPKPFGGK"
     gene            2205..2603
                     /locus_tag="KR294_002740"
     CDS             2205..2603
                     /locus_tag="KR294_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240805.1"
                     /translation="MSNNKKKKRKKNNNYKNAKSTKSNKNTKKQMEKNQRTDYNIPTI
                     SFKSGLILIVSSLVSTVVFPLLLSIFGIDNRFGVVIGNSLITSFAVAYTRYFVETKRG
                     FSLGFFRLYILFALSFAIIGYFWIYKGIHI"
     gene            2865..3173
                     /locus_tag="KR294_002741"
     CDS             2865..3173
                     /locus_tag="KR294_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH0240806.1"
                     /translation="MRVLFVCSSGMSSAIAVNALQKEGAKNGIDIDVLAVGTQEFENE
                     VKNGWDIAMVAPQVRHRFDYLKAFADEVSVPCALIQAQAYSPLGGPKLLKQVQELLSK
                     "
     gene            3262..4608
                     /locus_tag="KR294_002742"
     CDS             3262..4608
                     /locus_tag="KR294_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH0240807.1"
                     /translation="MLDKFTEFLDTKLSTSMARLAEQRHLRAVRDGIVASLPLIIVGS
                     FFLILAFPPLPDSWGVTQYLKENAVTILLPYRMTFFIISVYSTFGIGYSLAKSYKLDG
                     LTGGLLATATFLLTIVPTAIEGLTPELLKIVEKSPELLAWYNSIPQGWQMPMANLGGG
                     SMFVAIVTSIIGVEIYRFTDKSKFKITMPEAVPASVTRSFEALTPAALIIILMAIVTY
                     FLGFDWHGFIAKLVTPLVSATDTLPSVIILIFLITFFWSFGIHGVSIIGSLARPLWIQ
                     LLDANTASYAAGQAVPGIAAEPFFQWFIWIGGSGATIGLALLLAFRAKSAYGKSLGKA
                     TVIPAIFNINEPIIFGAPIVLNPILIIPFVVAPIVMATVSWFAMSANLVSRVVVTAPW
                     TLPGPVGAYLATGGDWRASVLNLLCIAISIIIYYPFVKMYDKRLLHEEKVEEQEAY"
     gene            4841..5938
                     /locus_tag="KR294_002743"
     CDS             4841..5938
                     /locus_tag="KR294_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBH0240808.1"
                     /translation="MGRLGISIYPEKTTSKEIYDYIDKAAENGFTRIFSCLLSVKDTK
                     ENIIKKFKRINEYAKFKGFEVILDVNPRVFGELEISYKDLTFFKKTKADGIRLDIGFT
                     GSEEALMTFNPQNLKIEINMSNNTNYIDTIMDYQPNKENLTGCHNFYPHRYSGLNLEH
                     FIKCTERFNKYGLRTAVFVTSQNETTFGPWPVTDGLPTIEMHRNLPIDIQVKHIIAMN
                     NINDIIISNCYPTYEELKVLGSMRKDMVTFDVAIEENIREVEKKILFEEIHFNRGDIS
                     DSLIRSTQSRVKYKGYKFELFNTPKIIKRGDIVIESSEYGHYAGELQIALTDMKNSGK
                     SNVVGYIRKEELFILDYIKPWQKFNFKPSTK"
     gene            6037..6951
                     /gene="murQ"
                     /locus_tag="KR294_002744"
     CDS             6037..6951
                     /gene="murQ"
                     /locus_tag="KR294_002744"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HBH0240809.1"
                     /translation="MLIKTLENLVTEGRNKNTLQIDKEDTLGIIELINNEDKTVAYAV
                     EEQKESIAKAVNIIVDRMKQGGRLFYIGAGTSGRIGILDATECPPTYGVDFELVQAII
                     AGGNQAIFKAIEGAEDDKELGKQDIIDRGVTSKDVICGIAASGRTPYVIGAMEYAKEL
                     GCAVLSITMNPNSEMSKKADLPINIIVGAEVIMGSTRMKSGTAQKMVCNMLTTASMVK
                     MGKVYSNLMVDVKTSNEKLVERAKRIIMIATNVKYDVAEKFLEEADNSVKLAIFMIKS
                     GLDKDSAKSILDRQEGYISEALKSIEKL"
     gene            7061..7981
                     /locus_tag="KR294_002745"
     CDS             7061..7981
                     /locus_tag="KR294_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA reductase"
                     /protein_id="HBH0240810.1"
                     /translation="MYFLGVDGGGTKTTFTLVDEELNIVGTITKGTCHYNQIGFDNLT
                     KLLITGLEEVCKDAKINVEEITYAFVGLAGYGKIKEVLYALEVATKNAYSHINYTLGN
                     DVEIALAGSLNGEKGINIIAGTGSIAQALDKDGNLHRCGGWGYVLGDEGSAYYIGMAT
                     LKMFTMQSDGRCSKTKLYDLIKRHLNIENDYDIIKYVNDEIQGDRIEIAKFATICLKA
                     VIEGDNTASKIFDDAAYELSRLIIGLEHHFEQGTKIKVSYSGGVFKSGDLILEPLKKY
                     LNKTRFGIVRPVLTPDLGACLLAKKKYYSK"
     gene            7998..8849
                     /locus_tag="KR294_002746"
     CDS             7998..8849
                     /locus_tag="KR294_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBH0240811.1"
                     /translation="MSCILKLKQIYEDLTEVDKKIADYILNNTEAISKLSVSELASNS
                     KTSTASIVRFSRKMGYSGFGDLKIEIAKDLMGKENEYTYVDENYDCNIDSVINKITNK
                     NIETINQTRLLNEKDIIKEAVEQIIKAKNVYIFGVGGSALVALDLQMKLLRINKQAFT
                     SLDSHTQLMVSSNVDKEDIAIAISYSGESKEVIKSIENAKLKGCKVICITKYSDNHLS
                     KISDLKLVVPNIEKRLREGAISSRIAMLTLIDIIYISIIQENLNEAEQKLQETKRILD
                     YLNINNA"
     gene            9461..10522
                     /locus_tag="KR294_002747"
     CDS             9461..10522
                     /locus_tag="KR294_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="HBH0240812.1"
                     /translation="MKKIRKLTTKLLITTIVLISGMSMTVYGMTAKEVTAKTPKSYVT
                     GTNSVYGPKLSQAQLNSVAQATADFMNKKITKNMTTDAKILVAYNHIKNNTTYVDWNA
                     VEGANTAYTLVTKKGACSGMARSMKALCDAMGIESYYVHSTSNDHQWNLIRFGDGRLY
                     HVDIDANKSAGKDIIYKSLSHPLPFDKTAYPKVGAIVQTVKPEQTQKPAPPGKHTMLP
                     HQEGAKAVGNFGKKGEDINEKHVMYEGVRCSVVNSSVNTITFTGSESNLDPSNLTIAV
                     IGFMNTPYGMFALAPEGKPVEYPFKYDKPFSLDFSGKNRSGAELAKYCKKNDVTIKIE
                     ITDEKANIGLGQIMYVRYE"
     gene            complement(10638..11612)
                     /locus_tag="KR294_002748"
     CDS             complement(10638..11612)
                     /locus_tag="KR294_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240813.1"
                     /translation="MNNINSLKVIKLSLGCSLAIFIAWLLKLEYSMVAGVIVLLTVKD
                     TKRETLKGSIGKIYGFLLCTIFSYLCFNILGYNLTSFSIFIFIIIPLCFLLNIQDVIA
                     MCVVIASHYYLQGETSIKWILNEAGIFAVGTGIGVLINMYIPTNIHKIHEVQKKLQEE
                     VSIVLIDIADIIVNPKKENGYSRDLYTLNSLIDSSISETYDNINNTLLSDTRFFLEHM
                     DIIKSQRDILENLYSYVSQLNSTPPQAHILSAFIHKIGYTEFEAETGNLLLEELKRLM
                     LSMKNQPLPVDRTEFENRAILFLCLTELKQFLVNRKHAQILRDNNFYK"
     gene            12068..12949
                     /locus_tag="KR294_002749"
     CDS             12068..12949
                     /locus_tag="KR294_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline iminopeptidase-family hydrolase"
                     /protein_id="HBH0240814.1"
                     /translation="MKITEGYMPFKGFKTYYRIVGENTEGKKPLVLLHGGPGSTHNYF
                     EVLDKIAESGRQVIMYDQIGCGNSFVEGHPELFNADTWIEELIELRKHLGLDEIHLLG
                     QSWGGMQAIWYAIEYKPKGIKSYILSSTLSSAKLWEKEQKRRISYMSEVDQKALLDAV
                     NTGDYSSKEYNDALERFMEMYCAGEVTEDSPECLRRPKKSGSEAYIVGWGQNEFSPTG
                     TLSGYEFTDRLHEIKEPCLVTSGAIDLCSPYIAKTMYDRIPNSKWELFEYSRHMPFVE
                     ENEKYIKVLTEWLNAND"
     gene            13331..14134
                     /locus_tag="KR294_002750"
     CDS             13331..14134
                     /locus_tag="KR294_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240815.1"
                     /translation="MEKLRVIEMIKNNPNIIATIDNPTDEMKLLAIKENGLVLEYINN
                     PTREMQELAIDNNIRAIKFIDNPTEDMMIKAVNEGWSILDYIKNPTDKVIEMAINQAG
                     WAIKYAKNPSEELQLLAVRKNYDSIKFIKQPYESVQEEAVRISYDALRYIDSPSYNAE
                     LIAIKNNEAAISFITDLDKNKMLEFLKVNILVIKYILKKVSKDELESVLKEVLSKEDV
                     EEKYIRDFLNCSVIDRNSESIPIDKIMFIYKYGSKTAKKIAVDEKLKIM"
     gene            14146..15276
                     /locus_tag="KR294_002751"
     CDS             14146..15276
                     /locus_tag="KR294_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH0240816.1"
                     /translation="MNFIDTLKSVDLILSTGEVPLIVGESGIGKTALANKLAKENDWS
                     LIVIDGNLLKEGEIGGLPTIESYVGVNSNGYKTEKKTTVYAVHNKLREIDEEISKSKT
                     VLLFIDEINRCEHTVQQELMNLILNREINGYKLHDDVKILAAMNPSSKYGSDFDYQVV
                     DMDAAQENRFVWLNMESDHTQWIKWAIDEGIERKVIEFISTFPEYLHKINEDDVRATP
                     RSYERVSKIYKVYKEKNNSIPRAVFLNVVKGNVGKVIAEEFISFIESNSEPLISYEDV
                     FLGESIDESIVERVKNESHTRLYLSAMNILKDLELNIKNDKYESNHYINRFIEFLKMY
                     PVDLMIGIMKDIRNSYIEVYKKAIENEEFVKSYFESYSLIRG"
     gene            15280..16689
                     /locus_tag="KR294_002752"
     CDS             15280..16689
                     /locus_tag="KR294_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240817.1"
                     /translation="MENYFDKQAKELYNKASEIINTHSMLKANRANEKFDIDIPQDFK
                     YEFFSLVDKVNLSLMEEEDNFYGYFLFQMSREIRFDISSPTGVNFKGAKYVIYFNPII
                     FLTLDIKQMETTIKHEIHHILSMHLMRAKELKGKYSTLAINMAMDIVVNKFLNNLPPY
                     ATTLEWVNLKYSLKLEPYEPFEYYVEKIQTELDLMEVDEDGEEDDSDKYGDIEIDYSP
                     ERTHDIWDESNEIDENTLREFTEKFINSSQKGKVPAYLESMISSLKNSKGELPWNLYL
                     NRIMGTVENNKKKTITRRNRRQPNRLDLRGELRSHKSEIAVALDVSGSISDEEFKQAI
                     KEVLSIVKNYNHEITIIECDNEIRRVYKVRTEKDIKDRIRIGGGTRFSPVFEYANNKK
                     INLLVYFTDGKGENKLQVIPRGYKILWVISGRGDKISLKEPYGAVKKLTKVKTNDEIL
                     EINDVRNDGYSMNSQAPIL"
     gene            16900..17409
                     /locus_tag="KR294_002753"
     CDS             16900..17409
                     /locus_tag="KR294_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CarD family transcriptional regulator"
                     /protein_id="HBH0240818.1"
                     /translation="MVMFLFKIDDYIMYGMTGVCKVMDITNERFTNGIKKEYYVLSPI
                     YSNNTVIKIPVDNEKVPMRKLLSKINVLSLINDIPNMDTSWIDNEKLRSEQFKKILRG
                     GKCEELIKLVRSIDNNREYVKSIGKKTHQADDNIMKEAERLLNEEFATILDISPNEVS
                     SYISSHIPQ"
BASE COUNT         7305 a         1879 c         3197 g         5895 t
ORIGIN      
        1 ttaagtataa ttacagatag gttaagtagc atagaagata gtttggatat taagaatcag
       61 gttgcaaaga taaatttttt agtaaactct attttgtata gtagtagaag caacactatg
      121 tttgaagatg tatttataaa taaatttaat ttagaaaaat tggtaaaaat gtctataaaa
      181 aataattcat ttttgcttat aaaaaataat gtagaagtta gtttgaatga attagaaaat
      241 gatgtttaca cagattctaa atgcatgtca tatgttttag accaaattat taataatgct
      301 ataaagtatt caaaggaagt tggtaagatt gaatttaatt caaaaaagtt agaaaatgga
      361 gtggtattat ctataaaaga ttttggtata ggtataaatg aggaagatat atctagggtt
      421 tttgacaagg gatttacggg gaaaaatgga agaaatcaat tgtataagtc tactggaatg
      481 gggatgtatt ttgtaaagaa aatgatagat agtttagggc atgagattga ggtatgttcg
      541 aaaattggtt catatacaat ttttaatatc tacttttatg atatatcgga ttatttaagc
      601 atagatagtt aggttattag actataaaat ctatcatcat atacaaatcg acatatacaa
      661 taagaataaa tttagttctt gaaaatagtg aagatttaat tagtgcctta aatgatgctc
      721 catctatatt ataaaataat aattattata tatgaaaaac atatcagata ggtacctggt
      781 atgtttttta tttgtagtaa ctattttaat atggtttttg gagagagaat atgttttgtt
      841 tgtgaaaaaa aattacatgg tattacattg acactgaaaa taaattaatg taagatttag
      901 ctaaggtaaa aaacgtgtat aagattaact cgattaattt cgtaagagta aattatcgta
      961 attaaagatg aaataagatt aattctaaaa ttattaaact taataccttg atttggggag
     1021 gaataactat aaacttaaaa ggatgataac tatgtatagt gtaggtttaa tgtcaggaac
     1081 ttccttagat ggagttgatg cagtactagc tgaaattagt gggaatggta gaaatactaa
     1141 agttaagcaa atagaattta taactctaga aattcctaaa gatataaaag acgaaataag
     1201 aaagtgctgt atagaagagg aatcgagtgt tgatttaatc tgtagcttaa attttaagct
     1261 tggatattta tttagtaaag ctgtaaaatc agtgtgtcat aaagcaaact ttcatatagc
     1321 aaatttggat tttatcgcat ctcatggtca aacaatcttt catataccaa gaagttataa
     1381 taattttgta tcttcaacgc ttcaaatagg tgaaccagca gttatagcat atgaaacaaa
     1441 tacaaaggta atatctaatt ttagagtaat ggatatagca gcaggtggag aaggtgctcc
     1501 attagtacca tatagtgaat ttttattata tagtgataac aataaaaatt tagcacttca
     1561 aaatattggt ggaataggaa atattactat aatacctaaa tcatgtaaca tagatgatgt
     1621 atttgcattt gatacaggac caggaaatat gataatagat ggagtatgtc aaagattatt
     1681 taatagaaag tatgataaaa atggatactt tgcatcaaaa ggtaaaatta atgaagaaat
     1741 gttaaaagat ttgatgagtc ataagtatct tagtcaagcg ccacctaaaa gcactggaag
     1801 agaggtattt ggacaagttt atttggataa catgcttaac aaatataaac atgtagataa
     1861 atatgatttg atagcaacag taactatgtt tacggcaaaa gctatatatt ataattataa
     1921 aaacttcata cttccaaagg ttaatgtaga tactttatta attggaggtg gaggagctca
     1981 taatctaact ttaataggat atataaaaga gttattatta gaggttgaag tattaactca
     2041 agatgaatat gggtattctt ctgatgcaaa ggaggctttg gcatttgtaa tcttgggcaa
     2101 tgaaacatta aataattctt tttctaatgt aatatctgca acaggggcta aaaataaagt
     2161 tattttaggg aatataacac ctaaaccttt tggaggtaaa tgacatgtct aataataaaa
     2221 aaaagaaaag aaagaaaaat aataattata aaaatgcaaa aagtacaaaa agtaataaaa
     2281 atactaagaa acaaatggag aaaaatcaaa gaacagatta taatattcca actataagtt
     2341 ttaaaagtgg attaatacta atagtttcat ctcttgtaag tactgtagtt tttcctttgt
     2401 tattatctat atttggaata gataatagat ttggagttgt tataggaaat tcattaatta
     2461 catcttttgc agttgcatat acaagatact ttgttgaaac taagagaggt ttttctttgg
     2521 gattttttag actgtatatt ttatttgctt tatcatttgc aataataggt tacttctgga
     2581 tatataaagg aatacatatt taaaaaagta ttgagactat tttatgttaa taataagata
     2641 gtcttttttc ttttttaaga aaagatatga gtattttaag tagtgtgtaa ttttagacaa
     2701 aagaatgatt agataaataa agcaattaaa gcaagatata aatgcatgaa ataaaattac
     2761 aatttaaaat gtaaaatatg aaaaaatata tacaaacgta ttcctgtaat caaaaataca
     2821 tgctataatg attgaaaaga aataaaaaaa cagggggaat caatatgaga gtattatttg
     2881 tttgttcatc agggatgtca agtgctatag cagttaatgc attacaaaaa gaaggagcaa
     2941 aaaatggaat agatatagat gttttggctg ttggtactca agagtttgag aatgaagtta
     3001 aaaatggatg ggatattgct atggtagctc cacaagtcag acatagattt gactatttaa
     3061 aagcttttgc tgatgaggtt agtgtaccat gtgcattaat acaagcacaa gcttatagtc
     3121 cattaggagg accaaagtta ttaaaacaag ttcaagaact gttgagtaaa tagtagttgc
     3181 agtgttgtta gattagaaga aagttgattt tataaaaatt ttaatgataa taaaaataaa
     3241 tattaattaa ggagagaaaa gatgctagat aaatttacag aatttttaga cactaaatta
     3301 tcaacttcta tggccagatt ggcagaacaa cgtcacttaa gagctgtaag agatggaatc
     3361 gtagcttcat taccacttat aatagttggg tcatttttct tgatattagc atttcctcca
     3421 ttaccagatt catggggggt aactcagtat ctaaaggaaa atgcagttac aatattacta
     3481 ccatatagaa tgacattttt tattatatca gtatattcta catttggcat aggttatagt
     3541 ttggcaaagt catataagtt agatggattg acaggaggtt tattagctac agctacattc
     3601 cttttgacaa tagttcctac tgcaatagag ggtcttaccc ctgagttatt aaagatagtt
     3661 gaaaagagtc cagaactttt agcttggtat aattcaattc ctcaaggatg gcaaatgcca
     3721 atggctaatc ttggtggagg ttcaatgttt gttgctattg taacatctat aataggtgtt
     3781 gagatttata gatttactga caaatctaaa ttcaagataa ccatgccaga agcagttcca
     3841 gcatcagtca caaggtcttt tgaagctctg acaccagccg cattaataat aattttaatg
     3901 gctattgtta cttatttcct agggtttgat tggcatggct tcatagctaa attagtaact
     3961 ccattagttt cagccactga cacattacca tcagtaatta tactaatatt tttaataacg
     4021 tttttttggt catttggaat acatggtgta tcaataatag gttcattggc aagaccttta
     4081 tggatacaat tattagatgc taatacagct tcatatgctg cgggtcaagc agttccaggt
     4141 attgctgctg aacccttttt tcaatggttt atatggattg gaggttctgg agctacaata
     4201 ggcttagctt tacttcttgc atttagagca aaatcagctt atggaaagtc tttaggaaaa
     4261 gcaactgtaa taccagcaat attcaatata aatgaaccaa taatatttgg agcaccaata
     4321 gtattaaacc caatattaat aataccattt gttgtagcac caatagtaat ggcaacagtt
     4381 tcatggtttg ctatgagtgc taatttagta tccagagtag tagttactgc tccttggaca
     4441 ttaccaggac cagtaggggc atatttagcc actggtggag attggagagc ttcagttctt
     4501 aacttattat gtatagctat atcaataata atttactatc catttgtcaa gatgtacgat
     4561 aagagattgc ttcatgaaga aaaagttgaa gagcaagaag cttattaatt agaaactata
     4621 ttggaaatta aaaactatat tagattagta taaatttcaa agtataacag ttatgaaata
     4681 agtaacgaag atattttgtt gattgtttat aaaaaaagaa aaggtaaact tttctttttt
     4741 tataaatata tatgaaactt tttttcacca aatttttaaa aaagtttcgt gtaattcgaa
     4801 ataaatttaa acacatatag gatataagga gatgacacag atgggaagat taggaatatc
     4861 aatttatcca gaaaaaacaa catctaagga aatatatgat tatatagata aagctgctga
     4921 aaatggattt acacgtatat tttcatgttt attatcagtt aaagatacta aagaaaatat
     4981 aattaaaaaa tttaaacgta taaatgaata cgctaagttt aaaggttttg aggtaatact
     5041 tgatgtaaat cccagagtat ttggtgaatt agaaataagc tacaaagatt tgactttttt
     5101 taaaaagacg aaggcagacg gaataaggct tgatatagga tttacaggtt ctgaagaggc
     5161 attaatgact tttaatcctc aaaatcttaa aatagaaatc aatatgagta ataatactaa
     5221 ttatatagat acaataatgg actaccaacc aaataaagaa aacttgacag gatgtcataa
     5281 cttttatcca catagatata gtggattaaa tttagaacac tttataaaat gtacagaaag
     5341 atttaataag tatggattaa gaacagcagt ttttgtaaca agtcaaaatg aaactacatt
     5401 tggaccatgg cctgtaactg atgggcttcc aacaattgag atgcacagaa atctacctat
     5461 agatattcaa gtaaagcata taatagctat gaataatata aatgatataa taatatcaaa
     5521 ttgttatcca acatatgagg agctaaaggt attaggttct atgagaaaag atatggttac
     5581 atttgatgta gcaatagagg aaaatatacg agaagttgag aagaagatac tctttgaaga
     5641 aatacatttt aatagagggg acatatctga cagtctgata aggtctactc aatctcgtgt
     5701 taaatataaa ggatacaaat ttgaactatt taatactcct aaaataataa aaagaggaga
     5761 tatagtaatt gaaagtagtg aatatggtca ttatgcaggg gagttacaaa tagccttgac
     5821 tgatatgaaa aacagtggta aatcgaatgt agtaggatat ataagaaaag aagaattatt
     5881 tatattagat tatattaaac catggcaaaa gtttaatttt aaaccctcaa caaaataatt
     5941 tattatgaaa atattaattt attataaaaa tataattatg aaagttggaa ttaaaatgtg
     6001 tttaaaaatt taatattaag aaaatgagga aatgatatgt taataaaaac tttagaaaat
     6061 ttagttacag aaggtagaaa taagaataca ttgcaaatag ataaagaaga tacattaggc
     6121 ataatagaat taataaataa cgaagataaa actgtagcct atgctgttga agaacaaaag
     6181 gagagtatag caaaagctgt taatataata gtagatagaa tgaagcaggg aggtagatta
     6241 ttctatatag gagcaggcac cagtggtagg ataggaatac tagatgccac agaatgtcct
     6301 ccaacttacg gagtggattt tgagcttgtt caagctataa tagctggtgg aaatcaagca
     6361 atatttaaag caatagaagg tgctgaagat gataaagaac ttggaaagca agatataata
     6421 gatagaggag ttacatctaa ggatgttata tgtggtatag ctgcatcagg aaggactcct
     6481 tatgttatag gtgcaatgga gtatgctaag gaattggggt gtgcagtact atcaataact
     6541 atgaatccga atagtgaaat gagtaaaaaa gcggatttac caataaacat tatagtaggg
     6601 gcagaagtaa taatgggttc aactagaatg aaaagtggta cagctcaaaa aatggtatgt
     6661 aatatgttaa caacagcttc tatggttaag atgggaaaag tatactcaaa cttgatggta
     6721 gatgttaaga catcaaatga aaagttggtt gaaagagcaa aaagaataat aatgatagct
     6781 acaaatgtaa aatatgatgt tgcagaaaaa ttcttagaag aagcagataa tagcgttaaa
     6841 ttggctatat ttatgataaa aagtggttta gataaggata gtgcaaagag tatcctagat
     6901 agacaagaag gttatataag tgaagcttta aaatcaatag aaaaattgta aaataaataa
     6961 tagtactgat aacctttcaa tattaaaaaa acagcattgg aaggttattt ttagatatta
     7021 agtattgaaa gaattattaa agatattgta ggaggatagt atgtattttt taggtgtaga
     7081 tggtggagga acgaaaacaa catttacatt agtagatgaa gaattaaata tagtaggaac
     7141 cataaccaaa ggaacttgtc attataatca aataggattt gataatctaa cgaaattatt
     7201 aataactggg ttggaagaag tttgtaaaga tgctaagata aatgtagaag aaataacgta
     7261 tgcatttgtt ggacttgctg gatatggaaa aataaaagaa gtattgtatg cattagaagt
     7321 agcaacaaaa aatgcatata gtcatataaa ttatactcta ggtaatgatg tagaaatagc
     7381 attagcaggt tctttaaatg gggaaaaagg tataaatata attgcaggta ctggttcaat
     7441 agcacaggct ttagataaag atgggaatct tcacagatgt ggaggatggg gctatgtatt
     7501 aggagatgaa ggttcagcgt attatatagg aatggctacc ttaaaaatgt tcacaatgca
     7561 gtctgatgga aggtgttcaa aaacaaaatt atatgattta ataaaaagac atcttaatat
     7621 agagaatgat tatgacataa taaaatatgt aaatgatgaa atacaaggag atagaataga
     7681 aatagcaaag tttgctacga tatgtttaaa agcagttatt gaaggtgata atactgctag
     7741 taaaatattt gatgatgcag cttatgaatt aagtaggctt ataataggat tagagcatca
     7801 ttttgaacaa ggtacaaaga taaaggtatc ttattcaggt ggagtgttta agtcaggaga
     7861 tttaatatta gagccactta aaaaatattt gaataaaacg agatttggta tagtgagacc
     7921 agtgttgact ccagatttag gagcatgttt acttgctaag aagaaatatt atagtaaata
     7981 ggtagaggtg atagagtatg agttgcattt taaaattaaa acagatatat gaagatttaa
     8041 cggaagtaga taaaaaaata gctgattaca tacttaataa tacagaggct ataagtaagc
     8101 tttctgtatc agaattggcg tcaaactcaa aaacaagtac agcaagtata gttaggtttt
     8161 ctagaaaaat gggatattcg ggttttgggg atttaaaaat tgagatagct aaagatttga
     8221 tgggcaaaga aaatgaatac acatatgtag atgaaaacta tgattgtaat atagatagtg
     8281 ttataaacaa aattacaaac aaaaacatag agactatcaa ccaaacaagg ttgttgaatg
     8341 aaaaagatat aataaaagaa gcagttgaac agataataaa ggctaaaaat gtatatatat
     8401 ttggagtagg tggttcggct ttagttgcac tagatttaca gatgaaactt ttaaggataa
     8461 ataaacaggc atttacctct ttagatagtc atacacaact tatggtatct tcaaatgtag
     8521 ataaagaaga tatagctata gcaatatctt actctggaga atcaaaagaa gtaataaagt
     8581 ctatagaaaa tgcaaaatta aaaggatgta aggtcatttg tataactaaa tatagtgaca
     8641 atcatcttag taagattagt gatttaaagc tagtagtacc aaatatagaa aaaagactta
     8701 gagaaggagc tatttcttca agaatagcaa tgcttacgtt gatagatata atatatattt
     8761 ctataattca agaaaactta aatgaggcag aacagaaact acaagaaaca aaaaggatac
     8821 ttgattattt aaatattaat aatgcttaaa actaggttat atatcaacta aacaaataag
     8881 ttaggctata agcgtaagtc aataagaaat agataaatat ctaaaatatt gacttactta
     8941 ataataatat atagcatttt tataatacaa atgagttgtc ttaaaattga ttttttttaa
     9001 tcaaatttta agttcaactc cttttttata tttttataga tatatcctat attttcccag
     9061 aaaacgtatt gaatatacaa attataagaa gtataatgtt gttgggagag aatgtatgaa
     9121 atgtatacaa agttgatttt aactgtatta ttgataattc tctttactct taccattatt
     9181 aatgattgaa gacaatggta tttattatag gtcaaagatt ccgaatgtat taatcatcat
     9241 cattttctca aactaacagc aaataccctg atttgcgagt tgtattgtat acaaattatc
     9301 tagaaaatat ctattagatt ttccataaaa tttaaatatt tcacgaatgt atgaatggag
     9361 aaatatacat gttgacaatc caccttttta aatactaaat taattttatt aatggtagag
     9421 aataggaagt aacaatgttt tataaaggag aatattaagt atgaagaaaa ttaggaagtt
     9481 aactaccaag ttattgatta caacaatagt tttaatctca ggtatgagta tgacagttta
     9541 tggtatgaca gccaaagagg taacagcaaa aacaccaaaa agctatgtca ctggaaccaa
     9601 tagcgtatat ggtccaaagc tgtcacaagc ccaactaaac tcagtagcac aagcaacagc
     9661 agattttatg aacaagaaaa tcacaaagaa tatgaccaca gatgctaaga ttttagttgc
     9721 ctacaatcac attaaaaata acacaacata tgttgactgg aatgcagtag agggagcaaa
     9781 tactgcctat acattggtta ctaaaaaagg tgcatgctca ggaatggcta ggagcatgaa
     9841 agctttgtgt gatgctatgg gaattgaatc ttattatgta cacagcacat caaatgacca
     9901 ccagtggaat cttatccgtt ttggtgatgg gcgtttgtat catgtagata ttgatgctaa
     9961 taaatcagca ggaaaggata tcatatacaa gagtcttagc cacccattac catttgataa
    10021 gacagcatat ccaaaagttg gtgcaatagt acagacggta aaaccagaac agacacagaa
    10081 accagcacca cctggaaagc acactatgtt accacatcaa gaaggggcaa aggctgttgg
    10141 aaattttgga aaaaaaggag aagatataaa tgaaaaacat gtaatgtatg aaggtgttag
    10201 atgtagtgta gttaattcat cagtaaatac aattacattt acaggtagtg aatcaaattt
    10261 agacccatca aatcttacga ttgctgtaat aggatttatg aacacaccat atgggatgtt
    10321 tgcattagca ccagagggta aacctgttga atatcctttt aaatatgata agccattttc
    10381 tttagatttt agtggtaaaa atcgttctgg tgcagaatta gcgaagtact gtaaaaaaaa
    10441 tgatgtgact attaaaatag aaatcactga tgaaaaagct aatattggac ttggtcaaat
    10501 aatgtatgtt cgatatgaat aatgatttaa tcatgacagt agaataagtt ataaacattg
    10561 cgccctctta ctaggggcgc atttaatatt atatctgata ttttgtagtc aggtcaactg
    10621 ctagatttct ccccttttta tttataaaaa ttattatctc taagtatctg agcatgttta
    10681 cgattaacta aaaactgttt taactcagtc aagcatagga ataaaatagc tctattttca
    10741 aactctgttc tgtcaacagg cagaggctgg tttttcatac taagcattag tctctttaat
    10801 tcttcaagaa gaagattgcc tgtttcagct tcaaattcag tataacctat cttatgtata
    10861 aaagcagata gaatatgagc ttgtggtggt gtagaattta gttgagatac ataactatac
    10921 aaattttcta agatatcccg ttggcttttt ataatatcca tatgttctaa gaagaatcta
    10981 gtatcactta ataaagtatt attaatatta tcgtaagttt cagaaatact gctgtcaata
    11041 agtgaattta atgtatataa atctctacta tatccatttt cttttttagg atttacaata
    11101 atatctgcaa tgtctataag tacaatactc acttcttcct gtaacttttt ttgaacttca
    11161 tggattttat gtatatttgt tggaatatac atatttatta agacacctat tccagttcct
    11221 actgcaaata ttccagcttc atttaaaatc catttgatag aagtttctcc ttgaaggtag
    11281 taatgggatg ctatgactac acacatagca ataacatctt gaatatttaa caaaaaacaa
    11341 agtggtataa ttataaatat aaatattgaa aatgaagtca aattatatcc taaaatatta
    11401 aaacataaat atgaaaaaat agtacataaa agaaaaccat aaatctttcc aatggagcct
    11461 ttaagagttt ctcttttagt gtcctttact gtaagtagta ctataactcc agcaaccatt
    11521 gaatattcta attttaatag ccaagcaata aatatagcaa gagaacatcc aagagataat
    11581 tttattactt taagtgaatt aatattattc aaatgcaaac ctcctgtaaa tcaatataat
    11641 aaaattctaa cataaaacta atattgcttg aaaggtaagt aactatactt aattatttta
    11701 ttgccctatt tgtttagata caatcaatat aattttattt tatgaaaatt ttttgtaaaa
    11761 ttttaaattt agagactaac atgagaccac aaagaggaag tttattataa gaagaaaact
    11821 taaaattgat tttaaatagc aaatgaaaat aatcaaatat gtatatacta ttattaaaaa
    11881 ataaaattat atagttaata taattttata attggtttag tatagagatt tttaactttt
    11941 atgttatact atttataaaa gtaggtataa agattaaaat acataatcaa atatgtataa
    12001 gaggttttaa atagtattgt taatgaactt gattattgtt tataattaca aattggagga
    12061 gataaacatg aaaattactg aaggatatat gccttttaaa ggttttaaaa cgtattaccg
    12121 tatagtagga gaaaatacgg aagggaagaa gccattagta ttacttcatg gaggtccagg
    12181 ttctacacac aactattttg aggtattgga taagatagct gaaagtggta gacaagtaat
    12241 aatgtatgac caaattggtt gtggaaattc atttgtagaa gggcatcctg agctatttaa
    12301 tgcagatact tggatagagg agcttattga actaagaaaa catctaggac ttgatgaaat
    12361 tcatctgtta ggtcaatctt ggggaggtat gcaggctatt tggtatgcta ttgaatataa
    12421 accaaaaggt attaagtctt acatcctttc atctactctt tcttctgcaa aactttggga
    12481 gaaagaacaa aaaagaagaa tatcatatat gagtgaggtt gaccaaaaag cattacttga
    12541 tgcagtaaat actggagatt actctagcaa agaatataat gatgcattag aaagatttat
    12601 ggaaatgtat tgtgcaggtg aagtgacaga agattctcca gagtgcctga gaagacctaa
    12661 aaaatcaggt tctgaagcat atattgtagg atggggacaa aatgaatttt ctcctacagg
    12721 aactctttct ggatatgaat ttacagatag attacatgaa ataaaagagc cttgtctagt
    12781 aactagtgga gcaatagatt tatgttcacc atatattgca aagactatgt atgatagaat
    12841 acctaatagt aagtgggaat tatttgagta ttcaagacat atgccattcg ttgaagaaaa
    12901 tgagaaatat ataaaagtct taactgagtg gttgaatgcg aacgattaaa aactatataa
    12961 acttatataa aaaaatgagt gtctcaaaat gaacttttta gttcattagg cactcttttt
    13021 gcatgaaatc aaatatattt tcattatttg aacgataaaa tgaggcttat atctactttg
    13081 ggaaagtaat tttttattac tagcgttaga ttctaatcta attgtatacg tattgaaata
    13141 atagaaatat attggtgttt ataacttaat tttattgttt tttagaaatt tttttatata
    13201 ttggtataat tattctgttt aaatttgatt aaaaagtata ttaattataa taagaaacaa
    13261 ttatataaat aggaatagat tattataatt aatatagata taaaaataat tatagaaaga
    13321 aaggcacatt atggaaaaat tgagagttat tgaaatgata aaaaataatc ccaatattat
    13381 agctacaata gataatccaa ctgatgaaat gaaattgtta gctattaaag aaaatgggct
    13441 tgtactagaa tatataaata atccaaccag agagatgcaa gaactagcaa tagataataa
    13501 tattagagca attaaattta tagataatcc aacagaagat atgatgataa aagcagtaaa
    13561 tgagggatgg agtatactgg attatatcaa aaacccaact gataaagtta ttgaaatggc
    13621 tataaatcaa gcaggatggg caattaaata tgctaaaaat ccaagtgaag aattacaact
    13681 gttagcagta agaaaaaatt atgattcgat aaagtttata aaacaacctt atgaaagtgt
    13741 acaagaggag gcagtgagaa taagttatga tgccttgaga tatatagatt cacctagtta
    13801 taatgcagaa cttatagcta taaaaaataa tgaagcagct attagcttta taactgattt
    13861 agataaaaat aaaatgttgg aatttttaaa agtgaatatt ttagtgatta agtacattct
    13921 gaaaaaagta tctaaagatg aattagagag tgtattaaaa gaagtattat ccaaagaaga
    13981 tgttgaggaa aagtatatta gagatttttt gaattgtagt gttatagata gaaatagcga
    14041 aagtatacca atagataaaa ttatgtttat ttataaatat ggaagtaaga cagcaaaaaa
    14101 aatagctgta gatgagaaat taaagattat gtaggagaga gaaaaatgaa ttttatagac
    14161 acattaaaaa gcgttgactt aatattatcc actggagaag tacctttaat agtaggtgaa
    14221 agtggaatag gaaaaacagc tttagcaaat aagcttgcca aagaaaatga ttggagttta
    14281 attgttattg atggaaactt acttaaagag ggtgaaatag gtggtcttcc aactatagaa
    14341 tcttatgtag gagttaattc taatggatat aagactgaaa agaaaacaac agtgtatgct
    14401 gttcataaca aattaagaga aattgatgaa gagatatcta aaagtaagac agttctttta
    14461 tttatagatg agataaatcg ttgtgagcat acagtacagc aagaacttat gaatttaatt
    14521 ttaaatagag aaattaatgg atataaactg catgatgatg taaagatttt agcagcaatg
    14581 aatccatcaa gtaaatatgg ttcagatttt gattatcaag tggtagatat ggatgcagcc
    14641 caagaaaata ggtttgtttg gttaaatatg gagagtgacc atacacaatg gataaaatgg
    14701 gcaatagatg agggtattga aagaaaagtt atcgagttta tttccacttt tccagaatat
    14761 ctgcataaaa taaatgaaga tgatgtaaga gccactccta gaagttatga gagagtatct
    14821 aaaatttata aagtttataa agaaaaaaat aattctattc ctagagcagt atttttaaat
    14881 gttgtaaagg gtaatgtagg taaagttatt gcagaagaat ttataagttt tattgaatca
    14941 aactctgaac cattaatatc ctatgaagat gtttttttag gagaatctat tgatgagtct
    15001 attgtagaaa gagtaaaaaa tgagagtcat acaagacttt atctatcagc tatgaacatt
    15061 ctaaaagact tagaattaaa tattaagaat gataaatatg aatcaaacca ctatattaat
    15121 agatttattg aatttttaaa aatgtatcct gtagatttaa tgataggtat tatgaaggat
    15181 attagaaaca gttatattga agtatataaa aaagctatag aaaatgaaga gtttgtaaaa
    15241 tcatattttg aatcttatag tttaataagg ggataatgta tggaaaatta ttttgataaa
    15301 caagcaaaag agctttataa taaagcaagt gaaattataa atactcattc tatgctaaag
    15361 gcaaatcgtg ctaatgagaa atttgatata gatataccac aagattttaa gtatgagttt
    15421 tttagtcttg tagataaagt gaatttaagt cttatggaag aagaagataa tttttatgga
    15481 tattttttgt ttcagatgtc aagagaaata agatttgata taagtagtcc tacaggtgtg
    15541 aattttaagg gagctaaata tgttatatat tttaatccaa taatcttttt aacgcttgac
    15601 ataaagcaaa tggagactac aattaaacat gaaattcatc atatattatc tatgcatttg
    15661 atgagagcaa aggagttaaa aggaaagtat agtacattag caattaatat ggcaatggat
    15721 atagtagtaa ataaatttct aaacaattta ccaccatatg caactacctt agagtgggta
    15781 aatttaaagt attccttaaa acttgaacca tatgaacctt ttgaatatta tgtagaaaag
    15841 attcagactg aattagattt gatggaagtg gatgaagatg gtgaggaaga tgatagtgat
    15901 aaatatggag atatagaaat tgattatagc cccgaaagaa ctcatgatat atgggatgaa
    15961 tccaatgaga tagatgaaaa tacccttaga gaatttactg aaaaatttat taacagttct
    16021 caaaaaggta aagttcctgc ttatttagaa agtatgatat catcacttaa aaatagtaag
    16081 ggtgaattgc catggaattt atatcttaat agaataatgg gaacagttga aaataataaa
    16141 aagaagacta taacaagaag aaatagaaga caaccaaatc gtttagattt gaggggagaa
    16201 cttagaagtc ataagtcaga aatagcagtt gcacttgatg taagtggaag tattagtgat
    16261 gaagagttta aacaagctat taaagaagtt cttagtatag tgaaaaacta taatcatgaa
    16321 attacaatta tagaatgtga taatgaaatt agacgtgtat ataaagtgag aactgaaaaa
    16381 gatataaaag atagaattag gataggtgga ggtactagat tttctccagt ctttgagtat
    16441 gctaataata aaaagattaa tttgttagtc tactttactg atggtaaagg tgaaaataaa
    16501 ctacaagtaa tacctagagg gtataaaatt ttatgggtta tttctggaag aggagataaa
    16561 atttcattaa aagaacctta tggagcagtt aaaaaactta ctaaggttaa aacaaatgat
    16621 gaaatattag aaataaatga tgtaagaaat gatgggtact caatgaatag ccaagcacca
    16681 attttatagg tattcacagg agataagctg tattaattta ttttgatatg cttgttataa
    16741 aaatctaaaa aatacattaa tcaatggtta atgtattttt taattttaat aatataagtt
    16801 ttacttacat ttaagtctta aaatgtgtta aaatataata tatagcagat agttttggca
    16861 aggtggattt agttgtcaaa actatttttt ttattaagga tggtgatgtt tttgtttaag
    16921 attgatgatt atataatgta tggtatgaca ggagtctgca aagtcatgga tataacaaat
    16981 gaacgattta caaatggaat aaaaaaagag tattatgtat tgagtcctat ttattctaat
    17041 aatacagtaa taaaaattcc tgtagataat gaaaaagtac caatgagaaa gttactttct
    17101 aaaattaatg tgctttcatt aataaatgat attcctaata tggatacatc atggatagat
    17161 aatgaaaaat tgagaagtga gcaatttaaa aaaatactca gaggtggtaa atgtgaagag
    17221 ttaataaaat tagtaagaag tatagataat aacagagagt atgtaaaatc tattggtaaa
    17281 aaaacacatc aagcagatga taatataatg aaagaagctg aaaggttatt aaatgaagaa
    17341 tttgcaacta ttttagatat ttctcctaat gaagttagtt catatatttc aagtcatata
    17401 cctcaataaa gtgttttagt atcctttatt taatctattt taagtattat ttatgtatgc
    17461 tggttttggt aaaataaaat atataattaa attatataaa aaataatgat gattgtattg
    17521 aagaattaca gaatagtgcg gagagcctac tcctttaggt gtgagatgga tatcacttaa
    17581 agatttaaat tgttattgta gatgttttta atataaaaca agattaataa gtgtattgta
    17641 agctttaagt gaaattgata ctataatgag ttacttagat tttaaaatat ataatattat
    17701 aaaaaatcct tttaggtttt gaatgaataa gatggatact atgttgaata gaatccatct
    17761 tatttaagtt ttatttatgt tgtttatttg taagcattat ttttgtacat gaaaacacag
    17821 tgtaaaaata tgcttagaat tatgaagttt tattaaaaag atattcgaca aaataagact
    17881 aaaaatattc ttaaacttat aactaagata aagattgtat atttatagtg tagcctgaaa
    17941 aattgtggat gtacgaaatt tatttagtat tttattgaaa caaagtagaa gaagtactat
    18001 agtttatctt tgaatagatt gttatttttt agtgaaaaag ttattaggtt aatacataaa
    18061 tataatagct tataaatagt ttaagcatgt taaaaaagta gttattagag atatatagtt
    18121 acattgctta taagatactt aaaatgatag cattcactta tatttagaaa attaagataa
    18181 aaaatcattt ttatatagta aagcatacct aaatttagaa aataattgaa tttataaaat
    18241 taattaaata cataaaaaag tattcaatca acttaa
//
LOCUS       DAEPKC010000080        17774 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.080, whole genome shotgun sequence.
ACCESSION   DAEPKC010000080 DAEPKC010000000
VERSION     DAEPKC010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17774)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17774)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17774
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.080"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..246
                     /locus_tag="KR294_002754"
     CDS             <1..246
                     /locus_tag="KR294_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HBH0240819.1"
                     /translation="IVSILDSNFENSVFQEVKGDNLVFEYTNLKKANFNGTKLSGIDF
                     TTNNIEGIEIGIDDIRGAIFDVSQAIDLTKLMGIIIK"
     gene            387..1658
                     /gene="brnQ"
                     /locus_tag="KR294_002755"
     CDS             387..1658
                     /gene="brnQ"
                     /locus_tag="KR294_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HBH0240820.1"
                     /translation="MRDIFIVGFALFSMFFGAGNLMFPPFLGMESGKDWLIPLIGFVV
                     ADAGIAMLVIIATARCKGSMDDVLRRAGKGLARVMSVAALACLALLVIPRTCATTYEM
                     GIMPIFGDHGPVAKAVFSIIFFGLTLAFTIRSSKVIDIIGKYLTPALLLVLFVLIVKG
                     IISPAGPMSPEHMIDKNLFGEGISQGYQTMDALGAASMATIMLMSIIAKGYTSDKDQI
                     GMTIKAGFVACVFLAVVYGGLTYLGATVSTLYDTSIPQASLLVEITSILLYGQVGKVI
                     LGVIVALACLTTSTGLTASISTYFEGISKASYKQLVIGICVASMLISNLGVDSIIAIS
                     VPILQTIYPVLLAIVVMELAGKHIKNDNAFKGAAYVTLVISLLSAINGMTGAVPFIQS
                     LPLAGLGFNWVIPAILGGIVGNFIKSNKQVA"
     gene            1860..3047
                     /locus_tag="KR294_002756"
     CDS             1860..3047
                     /locus_tag="KR294_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3798 domain-containing protein"
                     /protein_id="HBH0240821.1"
                     /translation="MLRKITAFMLSICLIIGLTGCSLLVGKKDKEKIIDDFKVAVVTQ
                     PLSENKVQYNMVEEMAKEYEEENKIDKDKDGQTKVKQTIKHVVLPENFTSNIDSAINK
                     IVKLADDKEVQAIVVSTDQAGLLPALQKVKEKRPEIITISAPMGDDKNQLSQFVDVNL
                     GVSAEERGKVLAERSKEMGAKAFIHYASTDDLKDVNIAKRLEMIKETCKNIGLPFVQV
                     NTPNINTEEDKNKVKQFLNEDIEKQVKKYGKDINVFGVNEYMDEVILTKALELKYIVA
                     EQSNPSPIQTYPSVMGLKISEKDAQNYDKINDMISEKAKAFGMSNRLGGYPMPMDAFL
                     PSVAIYLATEMVKQDLTQEDVCDPDYLEAFTELRFGIGSEFTPLTEVLYNYQSVILSQ
                     LIY"
     gene            complement(3277..5301)
                     /locus_tag="KR294_002757"
     CDS             complement(3277..5301)
                     /locus_tag="KR294_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH0240822.1"
                     /translation="MDKKKLILITHDKLNSDHYKEELTNFFGDEIIIETQNILDGIKE
                     NLEGDVVLSLSPLTSNFLIKHFKEDIEIIHGTKALSKLGYEKMMKLPPGTKSLLMTTN
                     KTSAFEMATYLYKIGINHIDFVPTYPDCDEIYDLDTAITPGQIRFIPKYIKNIVDLGW
                     RKISLDTYMSLLVVLKLKNEKFIEKLYKLSKETLSHDFLNTSLDNISKLKTILYMTID
                     EIGDGLIFFNTFNKVTFVNKSLLNMLGLDEKLIKSPSLMEYMPNSFLDKITKNLNIDN
                     MIIYIDEIDKKFILSKKPFYLYKNIEGCLITLKDVNNIEILEQKIRSDSVKRGYVAKY
                     KFNNIIGNSSIIKDCIKKAKKMALTDNPILITGETGTGKEAFTQSIHNHSNRKNKPFV
                     AINCASLPSELLESELFGYEDGSFTGAKKGGKKGLFELAHTGTIFLDEIGDMPHDLQV
                     KLLRVLQEKEIRKIGGTSIIPIDVRILAATNKDLEKLIIENKFRMDLFYRISMFTLDL
                     PPLRKRLEDIPLLLESFLKELPYKNIKLDKSLLEALNSYTWMGNIRELRNCIEYMAYM
                     GSNYLTINDLPQNISSKLNNNHMSSNMSIFNDLNQYDKNICISILKSLHMKPMGRTKL
                     MKFMEYNVTEYEVRNMLEYLTRNGYLISSKGRKGSSITEKGIKIIENNII"
     gene            5691..6359
                     /locus_tag="KR294_002758"
     CDS             5691..6359
                     /locus_tag="KR294_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240823.1"
                     /translation="MSKLESTTEKVEVKWYGYVALILGALFFSGIFKDAPGPLKVLDF
                     NNVLGSFGTLGTINDGVGTLAANFRGDGGTGPRDGWLYALTLIPSVMFALGVVRVIDH
                     LDGMKAAQKLLSPLLKPLLGLPGFAGLTLIASLQSTDAAASMTKELKDDGYIDEKQKA
                     VFCAFQFSGASAITNFFASGAALFPFIGDVPIFIPLALILIMKFVGANLLRLYLNKFD
                     KGEA"
     gene            6361..6846
                     /locus_tag="KR294_002759"
     CDS             6361..6846
                     /locus_tag="KR294_002759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjiG family protein"
                     /protein_id="HBH0240824.1"
                     /translation="MSEVAKKEVKVKKGNVIDAFIGGARNGFQISTNSMAPNVIFGFA
                     IISVFNLTGLLDVIGTIFTPVMSIFGLPGVAATAIMTIFISMGGASGVIAGLFTAGQI
                     SQAHVAILLPMLLLSGAQIQFMGRLLGTAELKTKYYPHMFVIATLNGCIAMLIMNYFV
                     V"
     gene            6907..8028
                     /locus_tag="KR294_002760"
     CDS             6907..8028
                     /locus_tag="KR294_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 peptidase aminoacylase family protein"
                     /protein_id="HBH0240825.1"
                     /translation="METNKDYIEYVHKVYDYLHTIPEKGFEEYKTSEFVLKELEKMGF
                     ENINKGIAGTGIIVTIDSKKEGPVFAIRADMDALEFIIDGEKKMIHACGHDGHTSMLL
                     TAAKLIKERNLVKRGKLKILFQPGEEKLYGALRVIDSGLLDDVEEMVGMHLRPGQDCR
                     LGKAIPAMYHCASCIMEFTIKGITCHGSKPHLGVNAVDAVCLAVNAINAIRVNPAIPN
                     SIKVTNISVKGETYNNIPDEAFMALDIRAESNDIIEELKEKAIHAVKTAVSSINAEAV
                     LISKDGVPAAEFDEELVNLAEETIKDVLGADASIGIFKNSGGEDFHYYTQKLKCKTTY
                     IGLGADATPGFHNPNVTFDTKALEYGVDIWCRLVEKRLG"
     gene            8309..9499
                     /locus_tag="KR294_002761"
     CDS             8309..9499
                     /locus_tag="KR294_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBH0240826.1"
                     /translation="MSKYNFDRVIDRVGTDCVKWDFRTNCSTKAQKDGLPFWIADMDF
                     ECAEPIIEALRKKVEHKIFGYSSNDSDKYFNAVCDWYKRRFNWEINRKDIIFSPGVVP
                     AVAILVRILTNSNEGVIVQKPVYYPFEAKIKSNNRDVVNNPLIYENGTYRMDYDDLEE
                     KAKCSNNKVLILCSPHNPVGRVWREDELKKVVEICKKYDLWIIADEIHSDLIRKGFKH
                     TPLQSLCPEYKDKIVTCIAPSKTFNLAGMQLSNIIVNNDELKKKYQEEVTAVGVATSP
                     NPFAIVATIAAYNESEDWLNELNDYLDNNIQFIDEYLKENLPKVKLVYPEGTYLAWLD
                     FTAYGLNEVELEDLMFKKANVLFDEGYIFGKEGIGFERINVACPQSLLKECMDRLKTI
                     FENL"
     misc_binding    9633..9888
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            9947..10948
                     /locus_tag="KR294_002762"
     CDS             9947..10948
                     /locus_tag="KR294_002762"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HBH0240827.1"
                     /translation="MSTIIPKDYKSSLNVIDTQIAIKKLKDFFEMRLSNELNLIRVSS
                     PLFVLPETGANDNLNGEKAVSFDIPFMNKNAEIVQSLAKWKRLALKKYGFEVGSGLYT
                     DMNAIRKNEELDNIHSLYVDQWDWELVIDKSSRNEKTLKDVVKRLYGVFKDTEIFVCS
                     MYEGIKEILPEEITFITSQELEDMYPELSPKEREDKIVKEKKAVFITQIGKTLISGEK
                     HDGRSPDYDDWELNGDILFYNPVLDSALELSSMGIRVDEESLDRQLKLAGCEERKEFD
                     YHKMLLNGELPYTIGGGIGQSRICMYFLQKAHIGEVQVGVWPQDMIQNCSSAGIELL"
     gene            11052..11441
                     /locus_tag="KR294_002763"
     CDS             11052..11441
                     /locus_tag="KR294_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1232 domain-containing protein"
                     /protein_id="HBH0240828.1"
                     /translation="MEFLKIIINIVLDILKKILVRFKNAKFGLVFVFDLLKLPDFMTD
                     KRINIVDKIKVISVLIFTISYFVSGVDIIPEMIAGAFGFIDDAIVLIWSIGIVNEEIN
                     KYRVIAKKDKHSNIIENVEFSIKDEEE"
     gene            11602..12810
                     /locus_tag="KR294_002764"
     CDS             11602..12810
                     /locus_tag="KR294_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dicarboxylate/amino acid:cation symporter"
                     /protein_id="HBH0240829.1"
                     /translation="MKKKIGLVPKLIIGIIVGILIGSYAPEIIVQILVTVSTLFSAFL
                     KFVIPFIIIGFVTAGIADLATGAGKLLGITTGIAYGSTLIAGLLSFAVSTLIFPNFID
                     ASVASQIGDPEAGMLAPIFTIPLEPMVDVTAAIVFAFVMGLGISALRNHGKGETLFNF
                     FQEFQGIVTKTLSTVIIPLLPLYIAGTFANITIAGEVWTILGVFWKVYLVVIPLHFVY
                     MACQFTAAGVFSGKNPVRMLKNQVPGYLTAIGTQSSAATIPVNVGCAEKNGVSKQIRE
                     FVVPLCATIHLSGSMISITGFTTAVLMMNGMPHGIGVLFPYIAMLGIAMVAAPGAPGG
                     AIMSALPFLPMVGIPSDGGLASLMIALYLTQDSFGTACNVSGDNAIAVVVDKINDGMS
                     KKGNKEEQSA"
     gene            complement(12896..13972)
                     /locus_tag="KR294_002765"
     CDS             complement(12896..13972)
                     /locus_tag="KR294_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003415975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBH0240830.1"
                     /translation="MSTNHGANLYSLSSKYGFSKEEFMDFSSNINPFGTSSLAKQYIV
                     NNIDMVSMYPDPDYIDLKTSISNYCKCSIDNIVLGSGATELISSFIHTINPKQALLLS
                     PAYSEYEKELSKINCSIEKYFAKEEDNFHINLENLIKTINAKDYDLVVICNPSNPTGF
                     AFTKVEVREILKNTDSFLMIDETYVEFTDTDTYSCTQLVDDYSNLFVIRGTSKFFSTP
                     GIRLGYGLISNTNVKNEINKNLDLWNINIIASKMGEIMFSDLDFISNTISLMNTERDY
                     LLKELKNIKSLDIYNTKGNFILCKIKTKELTAKSLREQLLPQKIIIRDCCSFEGLDEY
                     FFRVCILKPNENKLLISSLKAIFK"
     gene            14201..14728
                     /gene="hpt"
                     /locus_tag="KR294_002766"
     CDS             14201..14728
                     /gene="hpt"
                     /locus_tag="KR294_002766"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HBH0240831.1"
                     /translation="MYKVTGKMLTEEQIKEKVYELGKKIEEDFKGEDLLVVGILKGAS
                     VFVSDLIRCIDLDVNIDFMSVTSYGNSTESSGTVKILKDLDVDIEGKNVLIVEDIIDS
                     GLTLSNLVAALKTRNPKSLKLCTLLDKPQRRKANIPVDYVGFVIEDKFIVGYGIDYAE
                     KYRNLPYIGIVEDVE"
     gene            14817..15749
                     /locus_tag="KR294_002767"
     CDS             14817..15749
                     /locus_tag="KR294_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HBH0240832.1"
                     /translation="MDIQLNILLFFQNLRNPILNFIFLVFTISTEAPLLILITTIIYW
                     CINKKCGQKILFAIIGNFVVNLGIKEFVKAPRPIGIKGLESLRVSTAGGYSFPSAHTQ
                     TATTFWVSIMTIFKKRYLHLIGAVMVLGVGLSRLYLAVHWPIDVIAGWILGIFFTVVF
                     VKIFDYIDDNKNYILLVVLLIPFIIVAIFLNSPEYFEKFGIIVGFVFGYMVEDRFVKF
                     NTDNNNKKINFSNKNKGSKNIIFSRICRFLVGIVTIGMLYIGIKLFISMLIVTLNISD
                     STMSIIFMNFIKNTVVVFYGIAGAPALFKLLKLN"
     gene            15811..17037
                     /locus_tag="KR294_002768"
     CDS             15811..17037
                     /locus_tag="KR294_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBH0240833.1"
                     /translation="MKKVVIIGGGPAGMIAASTACEKGYDVTLIEKNHKLGKKLAITG
                     KGRCNITNACEIEELIENVPTNGKFLYSAFYTFTNDDVISMFNNLGVKTKTERGKRVF
                     PESDKAFDIVNALERQLKSKKVNILLNSKVEKIISKNNKIEKVILNDKKEIKCDSVVV
                     ATGGLSYPLTGSTGDGYKFAISQGHTIIDTKPSLIGIEVQESFTKDLEKLSLRNVEIR
                     VFNSKQKKVYSDFGELEFTKFGLDGPIIKSASCRMKDTRKENYTILLDLKPALDEEKL
                     DKRVQKDFQKYTNKKFEKALDDLLPKKLIPIIINLSEINPNTVVHQISREQRKNLVHL
                     LKNLKFTVKRYRPIEEAIITSGGVKVNEINSSTMESKLVEGLFFAGEVIDIDAYTGGF
                     NLQIAFSTGYLAGFNC"
     gene            17121..17342
                     /locus_tag="KR294_002769"
     CDS             17121..17342
                     /locus_tag="KR294_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000002841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta-type small acid-soluble spore
                     protein"
                     /protein_id="HBH0240834.1"
                     /translation="MASNNNNNRTVVPGAKEALNQMKLEIANELGMSNYQQVDKGNLT
                     ARENGYVGGYMTKKLVEMAEQQMAGKSNR"
     gene            17531..17701
                     /locus_tag="KR294_002770"
     CDS             17531..17701
                     /locus_tag="KR294_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240835.1"
                     /translation="MSSVNFEDLKNKFINSDLDEKIRIYTTTEGLSVEQFKELLKYYP
                     IQHLSKLEKALG"
BASE COUNT         6688 a         1959 c         3065 g         6062 t
ORIGIN      
        1 atagtttcta tcttagattc aaattttgaa aattctgtat ttcaagaagt aaaaggtgac
       61 aatctagtat ttgagtatac aaatttaaaa aaagcaaact ttaatggaac taaactttct
      121 ggcatagatt ttactactaa taatattgag ggaattgaga ttggtataga tgatattaga
      181 ggagcaattt ttgatgtgtc acaagcaatt gatttaacga aattgatggg aattatcata
      241 aaatgaaaaa aatattcata aaataaattg ggaaaacgtt aacaatgtgt gaatttttac
      301 cagattgaca tttttctgaa aataaagtaa gattatctta atattcaaaa tattttcaaa
      361 gggggtaatt tagtgtgagt aagcagatga gagatatttt tatagttggt tttgctttat
      421 tttctatgtt ctttggtgca ggaaatctta tgtttcctcc atttttaggg atggaatccg
      481 gcaaagactg gttaattcct cttattggat ttgttgttgc agatgctggt atagcaatgc
      541 ttgttattat agcaacagca agatgtaagg gaagcatgga tgatgtactt aggagagctg
      601 gtaaagggtt agcaagagta atgagtgtag ctgctctagc atgtttagca cttcttgtaa
      661 taccaagaac ttgcgcaaca acatatgaaa tgggtattat gcctatattt ggagaccatg
      721 gtccagtagc taaagctgta ttttcaataa tcttctttgg gctaacttta gcatttacta
      781 ttaggtcttc taaggttata gacataatag gtaagtattt aactccagcg ttattattag
      841 tattatttgt tttaatagta aagggtataa tttctccagc aggacctatg agtcctgagc
      901 atatgataga taaaaatcta tttggtgaag gtatatcaca aggttatcaa acaatggacg
      961 ctctaggtgc agcatctatg gcaactataa tgttgatgtc tataatagct aaaggatata
     1021 catcagataa agaccaaata ggaatgacta ttaaagctgg ttttgtagcc tgtgtatttc
     1081 tagcagtagt atatggtggt cttacttatt taggtgcaac agtttcaact ttatatgata
     1141 ctagtatacc tcaagcatct ttattagttg aaataactag tatattgtta tatggtcaag
     1201 taggaaaggt aattttaggt gtaattgtgg cacttgcctg tctgactact tctacaggtt
     1261 taacagcatc aatatcaact tattttgaag gaataagtaa ggcgagttat aaacaactgg
     1321 ttataggtat atgtgtagct agtatgctta tatcaaattt aggtgttgat tctataatag
     1381 ccatatcagt tccaatccta caaactatat atcctgtttt attagcaata gttgttatgg
     1441 agttggctgg taaacatata aagaatgata atgcttttaa aggtgcagca tatgttacat
     1501 tagtgattag tttattatca gctataaatg gaatgacagg agctgttcca tttatacaaa
     1561 gcttgccact tgcaggtttg ggctttaact gggtaatacc agctatattg ggtggaatag
     1621 ttggtaactt tataaaaagc aacaaacaag tagcataata atttgtaatt aatttaattt
     1681 tataatatat taatttttag tactatgggt aggtttaatc taaacctaat ctacccatag
     1741 tactttttag attggattat aatagcatgt atataatttt ttataatata atttttcttt
     1801 gaagtatgat aaaattagta atagtgataa gaatgtacaa atttaggagg ttttaattaa
     1861 tgcttagaaa aataacagca tttatgctat ccatatgttt aattattgga cttacaggtt
     1921 gtagtttact tgtaggcaag aaagataaag agaaaattat agatgatttt aaagttgcag
     1981 tggtaactca accattatct gaaaataaag tacaatacaa tatggtggaa gagatggcaa
     2041 aagaatatga ggaagagaat aaaattgata aagacaaaga tggtcaaact aaagttaaac
     2101 aaactataaa gcatgttgta ttgccagaga attttacttc taatatagac agtgctatta
     2161 ataagatagt aaagttggct gacgataaag aagttcaggc tattgtagtt tcaactgacc
     2221 aagcagggct tttacctgct ttacaaaagg taaaggaaaa gcgtccagaa ataataacta
     2281 tttctgcccc tatgggagat gataaaaacc aattaagcca atttgttgat gtgaatctag
     2341 gggttagtgc agaggaaaga ggaaaagtat tagctgaacg ttcaaaagaa atgggagcaa
     2401 aagcttttat tcattatgcc tctacagatg atttgaaaga tgttaatata gccaaaagat
     2461 tagaaatgat taaagagact tgcaaaaata taggattgcc atttgtacaa gttaatactc
     2521 caaatataaa tactgaagaa gacaaaaaca aagttaagca gtttttaaat gaagatattg
     2581 aaaaacaagt taaaaaatat ggaaaagata taaatgtatt tggtgtaaat gagtatatgg
     2641 atgaagttat attgactaag gctttagaat taaagtatat agttgcagag caaagcaatc
     2701 catcaccaat acaaacatat cctagtgtta tgggtctaaa aatatctgaa aaagatgctc
     2761 aaaattatga taaaataaac gacatgataa gtgaaaaggc taaggctttt ggcatgtcaa
     2821 atagacttgg tggatatcct atgccaatgg atgcttttct accatcagta gcaatttatc
     2881 ttgctactga aatggtgaaa caagatttaa cacaagaaga tgtatgtgac ccagattatt
     2941 tagaggcgtt tacagaatta agatttggaa tcggttcaga atttactcct ttaacagagg
     3001 tactttataa ttatcaatca gtaattttaa gccaattaat ttattaatat taaggaagtg
     3061 tctcaaaatg aactttttag tttatgaggc actctttttc tattaaatca aatatatttt
     3121 tatcttttta acaattaaaa agaagcttat ccctatattg agatagcttc gtttttaata
     3181 taaataagtt ttattatttt ataaaaaatt tatagaaaaa taaaaaatta taattatata
     3241 taaattttga taaagtaaag atgaattact ataggtttaa attatattat tttctattat
     3301 ttttatgcct ttctcagtta ttgatgagcc ttttcttcct ttactagaaa ttaagtatcc
     3361 attgcgtgtc aaatattcta gcatatttct tacttcgtat tctgtgacat tatattccat
     3421 aaatttcatt aactttgtcc tccccattgg tttcatgtgc aatgatttta ggatagaaat
     3481 gcatatgttt ttgtcatatt ggtttaaatc attgaatatg gacatattac ttgacatatg
     3541 attattattt aattttgaag atatgttttg aggtaaatca tttattgtaa gataattgga
     3601 acccatgtaa gccatatatt caatacaatt tctcagttct ctaatattcc ccatccaagt
     3661 gtatgaattt aaagcttcta aaagactctt atcgagtttt atgtttttat agggaagttc
     3721 ttttaaaaat gattctaaaa gaagaggtat atcttctaat ctctttctaa gaggaggtaa
     3781 atctaaagtg aacatactta tcctataaaa taaatccatc ctaaatttat tttctataat
     3841 taatttctct aaatctttat ttgtggcagc taatattctc acatcaattg gaataatact
     3901 tgtaccacca atttttctaa tttctttttc ttgtaagact cttaaaagtt taacctgtaa
     3961 atcatgtggc atatctccta tctcatctaa aaatatagtg ccagtgtgag ctaattcgaa
     4021 taatcctttt tttccacctt tttttgctcc agtaaaagaa ccatcttcat atccaaatag
     4081 ttcactttca agtaattcac ttggtaatga agcacaattt attgctacaa aaggtttatt
     4141 ttttctattt gaatgattgt gtattgactg agtaaaggct tctttacctg ttcctgtttc
     4201 acctgttatt aatataggat tatctgtaag agccattttt tttgcctttt taatacaatc
     4261 ttttataata gaactatttc caataatatt attaaattta tatttagcta cataacctct
     4321 tttgacagaa tcacttctta ttttttgttc taatatttct atattgttta catctttcaa
     4381 tgtaattaag caaccctcta tatttttata aagataaaat ggttttttag aaagtatgaa
     4441 ttttttatct atttcgtcta tgtatataat catattatcg atatttaagt tctttgtaat
     4501 tttatctaag aaactatttg gcatatattc cattaaggaa ggtgatttta taagtttttc
     4561 atctagtccc aacatattaa gtaaagactt atttacaaaa gtaaccttgt taaaggtgtt
     4621 gaaaaatatt agaccatcac ctatttcatc aatggtcatg taaagtatag tttttaattt
     4681 agatatatta tctaatgatg tatttaagaa atcatgactt agtgtctctt tggacaattt
     4741 gtatagtttt tctataaatt tctcattttt tagttttaat actactaata atgacatata
     4801 tgtatctaat gagatttttc tccaacctaa atcaacaata ttttttatgt attttggtat
     4861 aaatctaatc tgacctggtg ttatagctgt atctaaatca tatatttcat cacaatctgg
     4921 atatgtcggt acaaaatcta tatgatttat accaatttta tatagataag tagccatctc
     4981 aaatgctgaa gttttattgg ttgtcataag taacgatttt gtacctggag gtagtttcat
     5041 cattttttca tatccaagtt ttgaaagtgc tttcgttcca tgaataattt caatatcttc
     5101 cttaaaatgt tttattaaaa aattactagt taaaggtgat agagaaagca ctacatctcc
     5161 ctctaaattt tcttttattc catcaagtat attttgtgtt tctatgatta tttcgtctcc
     5221 aaaaaagttt gttaattctt ctttgtagtg gtcactattc aatttatcat gtgttataag
     5281 gattaacttc tttttatcca ttttatttct cctaacaaaa tagtatttat ttttaaagta
     5341 tttaaagtat aaggcaagtt atattataca acaaatagta gtataaattt atatatttga
     5401 ttaaataata ggttttttta ggattttatc ctataaaaac ctattttaaa attatttttg
     5461 caagataagg aaaatagctt tttatattgt aatgtatatt ttaaataatt aataaaaaaa
     5521 tattatattt ttaaacttga aaagtaagta attataagct atttaatcac tggaataaat
     5581 ttacaataaa aaaataaata caaaggcttt atcattaagg tattggcata agttttgctt
     5641 attaaacaag tatactaata aaattcattt aaacaggagg gagaatttat atgagtaaat
     5701 tagaatcaac aacagaaaaa gttgaggtaa aatggtatgg gtatgtagca ttaatattgg
     5761 gagcattatt tttttcagga atatttaaag atgcaccagg accattaaaa gtattggatt
     5821 ttaacaatgt attaggttct tttggaacat tgggaacaat taatgatggt gtaggtacat
     5881 tagctgcaaa ctttagaggt gatggaggta ctggccctcg agatggatgg ctatatgcat
     5941 tgacattaat accatcagtt atgtttgcac ttggagtagt tagagttata gaccacttag
     6001 atggaatgaa ggcagctcaa aagcttctta gtccactatt aaagccatta ttagggttac
     6061 ctggatttgc aggactaact ttgatagcta gtttacagtc tacagatgca gctgcatcta
     6121 tgactaaaga acttaaagat gatgggtata tagatgaaaa acaaaaagct gtattttgtg
     6181 catttcaatt ttcaggtgcg tctgcaatta cgaatttctt tgcttctgga gcagcactat
     6241 ttccatttat aggagatgta ccaatattta taccacttgc tttaatatta attatgaagt
     6301 ttgttggggc gaacttactt agattatatt taaataaatt tgacaagggg gaagcttaac
     6361 atgagtgagg tagcaaaaaa agaagtaaaa gttaaaaaag gaaatgtgat agatgcgttt
     6421 attggaggag ctagaaatgg attccaaata agtacaaatt caatggctcc aaatgtcatc
     6481 ttcggttttg ctataatttc tgtgttcaat ttaacaggtc ttttggatgt aatagggaca
     6541 atatttacac ctgtaatgag tatctttgga cttccaggtg ttgcagcaac agctataatg
     6601 acaatattta tatcaatggg aggagcatct ggagtaatcg caggtttatt tacagcaggt
     6661 caaataagtc aagcacatgt tgcaattcta ttgccaatgt tattgctttc aggagcgcag
     6721 atacaattta tggggagact tttaggaaca gctgagttaa aaactaaata ttatccacat
     6781 atgtttgtta tagcaacttt aaatggttgt attgcaatgc ttataatgaa ttatttcgta
     6841 gtataggtaa ttataataaa gatttaatat aaatggaaag tttaaatttt aaggaggagc
     6901 tagattatgg aaactaacaa agactatatt gagtatgtac ataaagtgta tgattatcta
     6961 cacactatac cagaaaaagg atttgaagaa tataagacat cagagtttgt tttaaaagag
     7021 cttgaaaaaa tggggtttga aaatattaat aaaggaattg caggaactgg tattatagta
     7081 actatagatt ctaaaaaaga aggaccagta tttgctataa gagcagatat ggatgcattg
     7141 gaatttatca tagatggaga aaagaaaatg atacatgctt gtggtcatga tggtcatact
     7201 tctatgcttt taacagctgc aaagttaata aaagagagaa atttagtaaa aagaggtaag
     7261 ttaaaaatac tttttcaacc aggtgaagaa aaattatatg gagcattaag agtaattgat
     7321 tctggtttgt tggatgatgt agaagaaatg gtagggatgc atttaagacc tggacaagat
     7381 tgtaggttgg gaaaggcgat acctgcaatg taccattgtg ctagctgtat aatggaattt
     7441 acgattaaag gtatcacttg tcatggttct aaaccacatt taggagtaaa tgcagtagat
     7501 gctgtctgtt tagcagtgaa tgcaataaat gcaataagag taaatccagc tataccaaat
     7561 tctataaaag taacaaatat atcagttaag ggagaaactt ataataatat accagatgaa
     7621 gcatttatgg ctttagatat aagggcagaa agtaatgata taatagaaga attaaaagaa
     7681 aaagcaatac atgctgtaaa aactgctgta agttctataa atgcagaagc tgtactaatt
     7741 tccaaagatg gagtaccagc agcagaattt gatgaagaac ttgtaaactt ggctgaagaa
     7801 actataaaag atgtattggg agctgatgca tctataggta tatttaaaaa ttctggtgga
     7861 gaagatttcc attattatac acaaaaacta aaatgtaaaa ctacatatat tggattagga
     7921 gctgatgcta caccaggatt tcataatcca aatgtaacat ttgatacgaa agctttagaa
     7981 tatggtgtag atatatggtg tagattggtt gaaaagagat tgggataaca tccaaactaa
     8041 taattctaca tttaaaatta taattataga agttatagaa aaagattgct tatgttaatt
     8101 agaaaataat taatatgagc aatcttattt tgatataatg aaactgattt tggaatattg
     8161 aaaaaatatg atggaaaagt aattatattt taaatctatt ggacaaaaaa gtgatattat
     8221 tataatatta agaattgtaa aataatacca aagtgcatct agtaatagac ttaacaatta
     8281 taaaaatttt attcttagga gggaaaaaat gagtaagtat aattttgaca gagtaataga
     8341 tagagtagga acagattgtg taaaatggga ttttagaact aattgttcaa caaaagcaca
     8401 aaaagatggt ttgccttttt ggattgctga tatggatttt gaatgtgcag aaccaataat
     8461 agaagcatta cgtaaaaaag ttgaacataa aatatttgga tatagttcaa atgatagtga
     8521 taaatacttt aatgcagttt gtgattggta taaaaggaga tttaactggg aaataaatag
     8581 aaaagatatt atttttagtc ctggtgttgt acctgctgtt gctattttag taagaatatt
     8641 aactaattct aatgaaggtg taatagtcca aaaaccagtg tattacccat ttgaagctaa
     8701 gataaagagc aataataggg atgttgtaaa caatcctctg atatatgaga atggtactta
     8761 taggatggat tatgatgatt tagaagaaaa agctaagtgt agcaacaata aagtactgat
     8821 actttgtagt cctcacaacc ctgttggaag agtttggaga gaagatgaat taaaaaaggt
     8881 tgtagaaata tgtaaaaaat atgacctatg gataatagct gatgagatac attctgattt
     8941 aattagaaaa ggatttaaac atactccttt acagtcatta tgcccagagt acaaggataa
     9001 aatagttaca tgtatagctc caagtaaaac atttaatctg gcaggaatgc agttgtctaa
     9061 tataatagtg aataatgatg aactaaaaaa gaaatatcaa gaagaggtta cagctgttgg
     9121 agttgcaact tcaccaaatc cctttgctat tgtagctaca atagcagcat ataatgaaag
     9181 tgaagactgg cttaatgaat taaatgatta cttagataat aatatacaat ttattgatga
     9241 atacttaaaa gaaaacctac caaaagtaaa acttgtttat ccagaaggaa catatctagc
     9301 atggttagat tttactgctt atggattaaa tgaagtagaa cttgaagatt taatgtttaa
     9361 aaaagctaat gtattatttg atgaaggtta tatatttgga aaagaaggaa taggatttga
     9421 aagaataaat gtagcttgtc cacagtcttt attaaaagaa tgtatggaca gattaaagac
     9481 tatatttgaa aatttataaa gtataggtaa aaatttataa agtgtttaaa aataaaaaaa
     9541 taataaactt gacaaatttt aactaatcac ttatcatact attatgaata aatagaaaac
     9601 ataagagagc taaattttat tgaattaaac tcttaaagac tttgaaagga agagtagtta
     9661 tagaatgtaa ttaaagcgag ttggtgatgg tgtgagacca atatgaagtc tataatgaag
     9721 aacatcctgg agttgctaac cgaaatttta aaagagtagg cttagtcgga accaaaccgt
     9781 tatcatattg gggtgtatcg agtaatatct gtacattgtg agctgggttt gaatttattt
     9841 caaactaatc agggtggtac cgcggaaaag caacctttcg tcccttttat atagggatga
     9901 agggtttttt taatggaaaa atatataaat atagggagtg aatgatatga gcacaataat
     9961 accaaaggat tataaaagta gtttgaacgt aattgataca caaatagcta taaaaaaatt
    10021 aaaagatttt tttgaaatga gactaagtaa tgaattaaat cttataagag tttcttctcc
    10081 gttatttgta ttgccagaaa caggtgcaaa tgataattta aatggagaaa aggctgtaag
    10141 ctttgatata ccatttatga ataaaaatgc agaaattgtt caatcacttg caaaatggaa
    10201 aagattagcc cttaaaaaat atgggtttga agttggtagt ggtttatata cagatatgaa
    10261 tgcaataaga aaaaatgaag aattagacaa tatacattct ctttatgtag accaatggga
    10321 ttgggaattg gttatagata aaagtagtag aaatgaaaag actctaaaag atgttgtaaa
    10381 aagattgtat ggagtattta aagatactga aatttttgta tgtagtatgt atgaaggtat
    10441 aaaagaaata ttaccagaag aaataacttt tataacatca caagagttag aagatatgta
    10501 tccagaatta tcaccaaagg aaagagaaga taaaattgta aaagagaaga aagcagtatt
    10561 tataactcaa ataggaaaaa cattaatatc aggagaaaaa catgatggaa gaagccctga
    10621 ttatgatgat tgggaattga atggggatat attattttac aatcctgttt tagattcagc
    10681 attagaatta tcttcaatgg gaattagagt tgatgaagaa tctcttgata gacaattgaa
    10741 acttgctgga tgtgaagaga gaaaagagtt tgactatcat aagatgcttt taaatggcga
    10801 acttccgtat acaattggtg gaggaattgg tcagtcaaga atatgtatgt atttcttaca
    10861 aaaagctcat ataggagaag tacaagttgg agtatggcca caggatatga ttcaaaattg
    10921 tagtagtgca ggaattgaat tattataatt taaatataaa ctaattgata aaatttatat
    10981 ctaatatgtt catcaaatta attatatcgg ttataatgta gaataaccta taattataag
    11041 aggtgataaa tatggagttt ttaaaaataa tcattaatat agttttagat attttaaaaa
    11101 aaattttggt cagatttaaa aatgctaaat ttggtttggt ttttgtattt gatttactta
    11161 aactacctga ttttatgaca gataaaagaa tcaatatagt tgataaaata aaggtaattt
    11221 ctgtattaat ttttactata tcctactttg tatctggggt tgatataatt ccagagatga
    11281 ttgcaggggc atttggtttt atagatgatg ctatagtttt aatttggagt ataggtatag
    11341 tgaatgaaga aattaataag tatagagtta tcgcaaaaaa agataaacat tcaaatataa
    11401 ttgaaaatgt agaattttct ataaaagatg aagaagaata acaatttata tatgttattc
    11461 ttttttttat taacaaaaaa tggttaaatt gttgacggag aggtaaaact ctattatcat
    11521 aataagtgga tatccaatat ttaactaagt attcaatgtg caagaatgct taatttaaaa
    11581 aagttatgga gggtaaatat tatgaagaaa aaaataggtt tagtgcccaa actaatcatc
    11641 ggtatcatag tcggtatttt aatcggaagt tatgcaccag aaataatagt acaaatatta
    11701 gtaacagtta gtactttatt ctcagcattc ctaaaatttg ttataccatt tataattata
    11761 ggttttgtaa cagcaggtat agctgattta gcaacaggtg caggaaagtt attggggata
    11821 actacgggaa tagcatatgg ttctacctta atagcaggat tattatcatt tgcagtatct
    11881 acattaatct tcccaaattt tattgatgca agtgttgcaa gtcaaattgg agacccagag
    11941 gcaggaatgt tagctccaat attcacaatt ccattagagc ctatggtaga tgtaacagct
    12001 gcaatcgtat ttgcatttgt aatgggactt ggaatatcag ctttaagaaa tcatggaaaa
    12061 ggagagactt tatttaattt cttccaagaa tttcaaggaa tcgtaacgaa aacgttgtca
    12121 acagtgatta tacctttatt acctttatac atagcaggaa cttttgcaaa tataactata
    12181 gcaggggaag tatggacaat attaggggta ttctggaaag tatacttagt agtaatacct
    12241 ttacattttg tatatatggc atgtcaattc acagcagcag gtgtattttc aggaaaaaat
    12301 ccagtaagaa tgttaaaaaa tcaagtacct ggatatttaa cagctatagg aactcaatct
    12361 tcagcagcaa ctataccagt taatgttggt tgtgcagaaa aaaatggagt aagtaagcaa
    12421 ataagagaat ttgttgtacc tctttgtgca acaatacatt tatcaggtag tatgatatca
    12481 ataacaggat ttacaactgc agttttaatg atgaatggta tgccacatgg aataggtgta
    12541 ttattccctt atattgcaat gttaggtata gcaatggttg cagcaccagg agcaccaggt
    12601 ggggctataa tgagtgcact tcctttccta ccaatggttg gaataccatc agatggtggg
    12661 cttgcaagtt taatgatagc tttatactta actcaagaca gttttggtac agcatgtaat
    12721 gtatcaggag ataatgcaat agcagtagta gtagataaaa taaatgatgg aatgagtaaa
    12781 aaaggaaata aagaagagca aagtgcttag ttttttaata atcaaaaatg agttatctca
    12841 aatagagata gctcattttt tatggtataa aaaattataa aataaagtga tttttttatt
    12901 taaaaattgc tttaagagat gatattaata atttattttc attaggtttt aatatacata
    12961 ctctaaagaa atactcatct agaccttcaa atgaacaaca atctcttatt attatttttt
    13021 gtggaagcaa ttgttctcga agagatttag cagtcaattc ctttgtcttg attttacaca
    13081 atatgaaatt gcctttagta ttgtatatat ctaagctttt tatattctta agctctttaa
    13141 gcaggtaatc tctttcagtg ttcattaagg aaatagtatt tgatataaaa tctaaatcac
    13201 taaacatgat ttcacccatt ttagaagcta ttatgtttat attccataaa tctagatttt
    13261 tatttatttc atttttgaca ttagtgttag atataagacc atatccaagc cttattccag
    13321 gcgttgaaaa aaattttgat gtacctctta taacgaataa attagaataa tcatcaacta
    13381 attgagtaca agagtatgta tctgtatcag taaactctac ataagtctca tcaatcatta
    13441 aaaatgagtc tgtatttttt aaaatttctc tcacttctac tttagtaaat gcaaatccag
    13501 ttggattact aggattacag attactacca aatcataatc tttagcattg atagttttta
    13561 taagattttc taaatttata tgaaaattat cttcttcttt tgcaaagtat ttttctatag
    13621 aacaattaat tttagataac tctttttcat actctgaata ggctggagag agtaaaagag
    13681 cctgtttagg gttaattgta tgtataaatg atgaaattag ttctgtagct ccactgccaa
    13741 gtactatatt atctatagaa catttgcagt aattggatat agaagttttt aagtctatgt
    13801 aatcagggtc aggatacata gataccatat ctatattgtt tacaatgtat tgtttggcta
    13861 aacttgatgt accaaaagga tttatatttg agctaaaatc cataaattct tcctttgaaa
    13921 agccatactt actagataaa ctatataaat tagctccatg gtttgtgctc ataaaagtac
    13981 ctccaaaaat aaaattatat aatcgataaa aataactgat taatatatgt acatatagat
    14041 tataatacaa aggaatcgtt attccaaatt tttaatggaa aaagcaaaaa agtatggata
    14101 agctgttaat ttaggtttaa aaatgatgaa aaagatttta attgatattt tggtatgcta
    14161 taatatataa gttaatagaa ggaaagcggg aggatacaaa atgtacaaag ttacaggaaa
    14221 aatgttgaca gaagaacaaa taaaagaaaa agtttatgaa ttaggaaaaa agatagaaga
    14281 agactttaaa ggcgaagatt tactagtggt aggtatactt aaaggagcta gtgtatttgt
    14341 ttcagattta ataagatgta tagatttgga tgtaaatata gattttatga gtgttacaag
    14401 ttatggaaac tcaacagagt cttctggaac agttaaaata ttaaaagatt tagatgtaga
    14461 tattgaagga aagaatgtgt tgattgtaga ggatataata gattctggtt taacattaag
    14521 taatctagtt gcagctttaa aaactagaaa tccaaaatct ttaaaactat gtactctact
    14581 tgacaaacct cagagaagaa aagctaatat acctgtagac tatgttggat ttgttataga
    14641 agacaaattt attgttggtt atggaataga ctatgctgaa aagtatagaa atttacctta
    14701 tataggtata gttgaggatg tagaatagat ttaaatgtga atcaaaagca ctaatttcta
    14761 agggagttag tgctttttag ttaattatat aaaattttag taaaggagac atctatatgg
    14821 atattcagtt aaatatatta ttatttttcc aaaatttaag aaatccaatt ttgaacttta
    14881 tatttcttgt ctttacaata agcacagaag caccgttatt aatattaatt acaacaatta
    14941 tatactggtg tataaataaa aaatgtggac agaaaatact gtttgctata attggaaatt
    15001 ttgttgtaaa tttaggcatc aaagagtttg taaaagctcc cagaccaata ggaataaaag
    15061 gtcttgaatc attgagagtt tctactgctg gtggttattc ttttccaagt gctcatactc
    15121 aaactgcaac aacattttgg gttagtatta tgactatatt taaaaagaga tatcttcatt
    15181 taataggtgc agttatggtt ttaggagtag gattgtctag gctgtattta gctgttcatt
    15241 ggccaataga tgtgatagcg ggttggatat taggaatatt ttttacagtt gtatttgtaa
    15301 aaatatttga ctatattgat gataataaaa attatatttt acttgtagtt ttacttatac
    15361 catttataat agtggctata tttctaaata gccctgaata ttttgaaaaa tttggtataa
    15421 tagtaggatt tgtatttgga tatatggttg aggatagatt tgttaaattt aatacagata
    15481 ataataacaa aaaaataaat tttagtaata aaaataaggg gagtaaaaat ataatttttt
    15541 caagaatatg taggtttttg gttgggatag taacaatagg aatgttatat attggcatta
    15601 agttgtttat ttcaatgtta atagtcactt taaatataag tgactctact atgagtataa
    15661 tttttatgaa ttttattaag aatacagtag ttgtttttta tggaatagca ggagctccag
    15721 cattatttaa acttttaaaa ttaaattgat tttaaggtat agagtcaata gtttaaatta
    15781 aaaaaattaa gggtagaaaa gagtgattat ttgaagaagg tagtaataat aggtggtgga
    15841 ccagcaggga tgatagccgc atcaactgca tgtgagaaag gctatgatgt aacattaatt
    15901 gagaaaaatc ataaattagg aaaaaaactt gcaataacag gaaaaggtag atgtaatatt
    15961 actaacgctt gtgaaataga ggaattaata gaaaatgtac ctacaaatgg aaaatttctt
    16021 tatagtgctt tttatacttt tacaaatgat gatgtaataa gtatgtttaa taatcttgga
    16081 gtaaagacta aaacagaaag aggaaaaagg gtttttccag agagtgataa agcatttgat
    16141 attgtaaatg ctcttgaaag acaacttaaa agtaagaaag taaatatatt attaaattcg
    16201 aaagtagaaa aaataatatc taaaaataat aaaattgaaa aagtaatttt aaacgataaa
    16261 aaagaaatta agtgtgattc agttgtagta gcaactggtg gattaagtta tccacttact
    16321 ggttctactg gtgatggata taaatttgca atttcacagg ggcacacaat tatagataca
    16381 aaaccatctt taattggtat agaagtacaa gaaagtttta caaaagattt agaaaaatta
    16441 tcattgagaa atgttgaaat aagggtgttt aatagcaaac aaaagaaagt ttatagtgat
    16501 tttggagaac ttgaatttac taaatttggt ttagatggac ctataatcaa gtctgcaagt
    16561 tgtagaatga aagatacaag gaaagaaaat tacactatat tattagattt aaaacctgca
    16621 ttagatgagg aaaaattgga taaaagagtt caaaaagatt ttcagaagta tacaaataaa
    16681 aaatttgaaa aagcattaga tgatttactt ccaaaaaaac taatacctat aataataaac
    16741 ttaagtgaaa ttaatccaaa tacggttgtt caccaaattt ctagagagca gagaaaaaac
    16801 ttagtccatt tattaaaaaa tttaaagttt acagtaaaga gatacagacc tattgaagaa
    16861 gctataataa cttctggtgg tgtaaaagta aacgaaataa attcaagtac aatggaatca
    16921 aaattagtag aaggtttatt ttttgctgga gaagtaatag atatagatgc atatacaggt
    16981 ggattcaatt tgcaaatagc tttttctact ggatatttgg caggttttaa ttgctaaaaa
    17041 ttacctgaat taaaaatgtt taaaatcaca taatattatc agcaacacaa aataaattaa
    17101 acagaaggaa ggtaatcaac atggcaagta acaataacaa caacagaaca gtagtaccag
    17161 gagcaaaaga ggctttaaac caaatgaaat tagaaatagc taatgaactt ggtatgagta
    17221 attatcaaca agttgataaa ggaaacctta ctgcaagaga aaatggttat gtaggtggat
    17281 acatgactaa aaaattagtt gaaatggctg aacaacaaat ggctggaaaa agcaacagat
    17341 agttataaat aattatttat aactattggc tattagttta gctagagcta tctcaaatat
    17401 agaaagtaat ttctaaattg agatagcttt tttttattaa attattaaat agatatattt
    17461 ttatgtaata aattttatgt atttggataa aataatacaa atgaatatgt tacataagga
    17521 gtgatgtaaa atgagtagtg taaattttga ggatttaaaa aacaaattta ttaatagtga
    17581 cttagatgaa aaaataagaa tatatacaac aacagaaggt ttatcagtag aacaatttaa
    17641 agagctacta aaatattatc caatacaaca tttatctaaa ctagaaaaag cacttggata
    17701 gcagtattta atccaaaatt aaaaaggcaa tttatttaat attaaaaata ttttttatta
    17761 aataaattgc cttt
//
LOCUS       DAEPKC010000081        17700 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.081, whole genome shotgun sequence.
ACCESSION   DAEPKC010000081 DAEPKC010000000
VERSION     DAEPKC010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17700)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17700)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17700
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.081"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            129..1010
                     /locus_tag="KR294_002771"
     CDS             129..1010
                     /locus_tag="KR294_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBH0240836.1"
                     /translation="MPAYLFDSNSIANIYRVFPISFSFIVTGLYFSYKNNKNNKINFE
                     AVLEDKKNLIFLLSLMFGMYLYLCLSLSIYYTVGNVLILKLYGIKSAIIVLVGNYIAE
                     RYSFRITQIKGYDIKNQIEYVESVKTEYEINKLNDIVYTDLLTGFYNRPFVNQKLSEW
                     TSNHYKFTLCFTDLNSLKPVNDKFGHQFGDKYISTTAQIIKKLINVENSLLFRYGGDE
                     FLFLLQNTSCVEAEKIMININYELSKISNTDEYPYALSISYGLVEWDGISDIETLISK
                     ADSLMYENKLKNKSTLN"
     gene            1201..1368
                     /locus_tag="KR294_002772"
                     /pseudo
     CDS             1201..1368
                     /locus_tag="KR294_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418025.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
     gene            complement(1628..4195)
                     /locus_tag="KR294_002773"
     CDS             complement(1628..4195)
                     /locus_tag="KR294_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002602373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate, phosphate dikinase"
                     /protein_id="HBH0240837.1"
                     /translation="MIYYVLPLEHKQATIEIVGGKGMSLSKLLTAGIPVPDGFHVTTA
                     SYQIFVETNHIQSRINKLLDGIDSNNTSQLEDVSKKIGELFHNGEMPQEVSDAIKMAY
                     AGLGNISVAVRSSATAEDLPDASFAGQQETYLNIQGEDKVIDSVKRCWASLWTARAIA
                     YRVKNNIKHEIVALAVVVQKLAFSDSSGIMFTLNPINGRRSEMIINAAWGLGEAVVSS
                     LVTPDTIVVDKDSERIISYEVANKEIMTVRTSEGTEETMVPERLRKKYALTRNQVMQL
                     IQLGKKIEKYYQMPMDVEWALEKDKLYIVQARPITVLPPEWVLPEQDVVYTKGSLAEH
                     LPNPVTPLFATLGLEIVNRASELLWIDMFGKSAKKLLPKNGAYTVINGYVYLSAKSNP
                     LLIAIKSLSPRSLRRTLMNSVARWETARKGYEDAIKQWEEKPLHTMNAHQIMEGIQTI
                     FYAACIYFTRIQLTLPAASISETLFTKLFQGAVRRAGITDTSVFLLGFDTIVLQSEKE
                     LWGISEWVKQNNSINLYLQNSPAIKIAEDFMSSVVPVGVSQEVWIEWKNRINKYFKEF
                     GRTAYEFDFAHSTPQETLTPTFESVKTFVEGKGESPFLRQTTFEKRRKHAEEEILQHI
                     GGLRKKLFFKLLHWAQETSPMRENAIYLMGMGHPLIRCMFQEISERFIRGGAISHLDD
                     IYWLTKSELEVLIEQLDKNKSLSDMNGIIPVRKAELKKYMGYVSPSKLPEKNKKTISQ
                     AQQKQKDGKIVLTGIGTSTGVVTAPACVLNSPADFESFQPGSVLVAVTTTPAWTPLFS
                     SASAIVTDIGGPLSHSSIVAREYGIPAVMATHIATRAIKSGQMITVDGLAGTVTFDE"
     gene            complement(4198..4803)
                     /locus_tag="KR294_002774"
     CDS             complement(4198..4803)
                     /locus_tag="KR294_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002591427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH0240838.1"
                     /translation="MPKGIVLTPEQQAERREKIVAVALSLMAENGFQKTSMREIAVLA
                     NMGKSSLYDFFKTKDEIVVYAVEKEIEKTIQQVHRIIDGEPSPQQCLRKIMLNHLRFP
                     EQYRTVLMWLNTESDYLEEEYRKRLKDARYAYQDIIKSVIDNGVTTGIFRKTDTALVT
                     RLLINSMLSISYTSRPLDSSEKMLDETMNIFLHGIMNDGGE"
     gene            complement(5177..6637)
                     /locus_tag="KR294_002775"
     CDS             complement(5177..6637)
                     /locus_tag="KR294_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HBH0240839.1"
                     /translation="MFNELKTKENVYKNLINGKWVESNSRKPIEIYSPIDNSLVGKVQ
                     SMTKHEVDEVIKNTKESIKVWAEMPVYKRANIFHKAADLLLENIDEIANILVLEIAKD
                     IKSARAEVERTADFLRYTADVGKNMEGEAISGDNFPGGTRNKMSYVSRVPLGTVLAIS
                     PFNYPVNLSMSKIAPALIGGNAVVLKPATQGAISALHVVEIMRKAGIPDGVLNTITGR
                     GSEIGDYVVTHKGINFINFTGSTEVGQHISKISGMVPLLLELGGKDAAIVLEDADLDF
                     AAKNIVSGAYSYSGQRCTAVKRILVQESVADKLVGKIKPLVEKLTIGNPMDEVVITPL
                     IDNKATDFVQGLVDDALHKGAKLITGNVRKNNLFYPTLLDNVNVDMKIAWEEPFGPVL
                     PIIRVKDINQAIEIANQSEYGLQSSVFTSDIDKAFYIADKLEVGTVQINNKTERGPDH
                     FPFLGVKASGMGTQGVKYSIEAMTRPKAVVVNVREL"
     gene            6991..7569
                     /locus_tag="KR294_002776"
     CDS             6991..7569
                     /locus_tag="KR294_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH0240840.1"
                     /translation="MAKSFTEIEKDNIRKRLISECEINWSKYGYKKTNIDELCSKSGI
                     AKGSFYTFFDSKEKLFFEVLNGIQNRLISSVDEILSNMPPKEGFAKALKMLYRLYDKN
                     PFLYSPNNTDYITLLNKIPKEMLSQLEYSNVQSFYSLIERHNLKLKIEKEKAFGVCNA
                     LLSSLLLKEDIGYDYIEVFDFMVDNLVEHILE"
     gene            7620..7853
                     /locus_tag="KR294_002777"
     CDS             7620..7853
                     /locus_tag="KR294_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240841.1"
                     /translation="MIELIQRLNDIIYKINDKLNIHTKLVDPSSELMPLYSMLSIIVS
                     IFLIILGIKVRKKFLIIIAIISIIINILIILDR"
     gene            7862..9112
                     /locus_tag="KR294_002778"
     CDS             7862..9112
                     /locus_tag="KR294_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH0240842.1"
                     /translation="MVKSSNTFNKNFNLMILGQIISLFGASILKFALSLYILDITGKA
                     EIFATILAVSSIPIIVFSPIGGAIADIFNRRNLMVIFDFSSSLTVLILAVFLFNNNGS
                     ILLVGIIMTILSVISTMYQPTVQSSTPLLVDNEHLMNANGIVAGVASLTNIAGPVLGG
                     VLYGVIGINAIIVISCVSFFLSAIMEIFIQIPFIKQEQNSNIIKTIFTDIKDGIVHIC
                     KENRFILKILFLAIAINLFLSSMLIVGIPYIVKITMGASNFLYGLAEGAISFSSLVAA
                     VSIGIFSKHLKITNLHISFIICAVMFIPMAVSVYPFILNTGFPVPFLIFIVSSMLIFF
                     TTTLISIYVITVTQLKTPNELLGKVMSILFAGTAIAMPLGQVMYGKLFDLLSDRVYII
                     ILGVGFITLLIAFVSKITLRNENL"
     gene            9273..9842
                     /locus_tag="KR294_002779"
     CDS             9273..9842
                     /locus_tag="KR294_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HBH0240843.1"
                     /translation="MSYMPTLEQAWEILRKYNKEEFHIRHAQIVSGVMRYYAKEYDPE
                     RVEFWEIVGLLHDLDFEMYPDEHCVKQRELMTELDLDKSIIDSTISHGYGLTGSDVKP
                     EQFMEKVLFAVDELTGLIGAAAIMRPSKSVSDLELKSVKKKFKDKSFAAGCSRDVIRS
                     GAEMLGWELDKLIQTTIEAMRSLIPEMAI"
     gene            complement(10481..11821)
                     /locus_tag="KR294_002780"
     CDS             complement(10481..11821)
                     /locus_tag="KR294_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBH0240844.1"
                     /translation="MIKSSLFWNIFIAISFMIEWFLCKKMLDYTSEKRISNKKINFCV
                     VGIIVFADIIYFFDVPPNIRVIISMIITIAFYKISYDVGFIKSVLISLIYWMLLIATD
                     ALSISLTVWLNSINDMSSMGTGDIYRIESIILGKILLIVSLLLYRALKIKLNIEINKR
                     TLFYIVIPIVANIASFFVIFEYIFNPGSGSLIHNFQFVMISVVLLISSITLVLIAKKL
                     QQYNTLVVENNMIKNTLKYENEYYEDIEKKYLKTRLLSHDMKNHILCINAMIKKGIDV
                     TSYLNNLQVEIQSNDLLFNTGNFILDAILSEKKEVCDKNDIELKIGINFSCCEAVELV
                     DICHIFSNILDNAIEACNKIDSGNRVICVKGDVMQNFYLIRVENTKMNKIITKNGDIL
                     TDKKGSLHGLGIKSVKNSVNKYGGNVVIEYDDKKFVVKIAIPLRNVKKAVNHVI"
     gene            complement(12491..13582)
                     /locus_tag="KR294_002781"
     CDS             complement(12491..13582)
                     /locus_tag="KR294_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HBH0240845.1"
                     /translation="MIEKVEEKSKIIKTSKEYKRTIIEEKDKEWTKKLNDILSRSSFS
                     NDELDKIKALIPKEILTNENVGEVVTEDGYAKPEYDEVFKSLFTLNNEYDLLVNFIND
                     ILKDAPYANRNIKPFTQIKRIIRVETDPTINYIGEKRPKLDILAEDEENNHINIEMQR
                     AFENDYLERAEYYLSRVHGRKLEEGKEYKEIGKTIGIHILNHVKYNHIEDYVNCLRLT
                     MDGHPDIYSSKTALYFIELPKIHKSDYIVNRIMLWGKLISNPSNLDVRVIAKNDSIIK
                     KALDRLKELGSNEEYLLNLKRGAYIMNKSRNFKEEIERETAIRVAKEKDYKIIIMLKK
                     NGFKLDDILNKFNDFDLSEDEIKEVYENN"
     gene            complement(14350..16269)
                     /gene="thrS"
                     /locus_tag="KR294_002782"
     CDS             complement(14350..16269)
                     /gene="thrS"
                     /locus_tag="KR294_002782"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HBH0240846.1"
                     /translation="MIKVALKDGSIKEFENAISVMDVAKSISEGLARNVVAASVNGEV
                     VGLDHIIDTDCDLNLFKFEDKEGKEVFRHTSAHILAQAIKRLYPEAKLAIGPSIENGF
                     YYDIDLDHRLVPEDLEKIEAEMKKIAKEDLKIERFELPRNEALELMKEQGEDYKVELI
                     SDLPESEIISFYKQGDFTDLCRGPHLPSTKKVKAVKLQSVAGAYWRGDENNKMLQRIY
                     GTSFEKNKDLEEYLHLLEEAKKRDHRKLGKELGLFMIPEEGPGFPMFLPKGMELKNEL
                     LKFWREIHRKAGYIEIESPIILNRKLWETSGHWYHYKENMYTVKIDDEDYAIKPMNCP
                     GGLIYYNSQLHSYRDFPMRVAELGRVHRHELSGALQGLMRVRAFTQDDSHIFMLPEQI
                     KDEIKGVANLIDGIYKTFGFEYNLELSTRPENSMGSDEEWEAAENGLREALEELGLPY
                     TINEGDGAFYGPKIDFHLKDCLGRTWQCGTIQLDMQLPRQFDNTYIGQDGEKHRPVMI
                     HRVAFGSIERFIGILIEHYAGKFPVWLSPTQVKILPISDKFMDYANEVKKELFDKGIR
                     VELDDRAEKIGFKIREAQLEKVPYMLIVGEKEVADNNVSVRSRDKGEIGSIKLDEFIA
                     SISKEIESRESIIQD"
     misc_binding    complement(16333..16570)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(17029..17631)
                     /locus_tag="KR294_002783"
     CDS             complement(17029..17631)
                     /locus_tag="KR294_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF445 family protein"
                     /protein_id="HBH0240847.1"
                     /translation="MDNLIRILILAVIGGFIGYVTNVVAIRLIFRPIEPIKIPILNIE
                     IVGLIPKRRAEIAANVGEIIQEEFLSMDEILANIITDEDKEEVVRYIKARVKIIIHEK
                     VSFIPSGIKNMIQDYLGEIIESEVKQSIDELSKNIINKANERIDIQKMVEDKINELDL
                     YELEEIIIRIAKKELKHIEFLGLVLGFLIGIAQGLITMFI"
BASE COUNT         5967 a         3048 c         2164 g         6521 t
ORIGIN      
        1 tattcataca aattaaagta acttataaaa tctccacaat aaaaaacatt ttttattcac
       61 taaactgctc catcattggt ttagcaataa atatattttt taggtcttta atgtcaatag
      121 tgttaaatat gccagcatat ttatttgata gtaattctat tgcaaatatt tacagagtat
      181 ttcctatatc atttagcttt atagttacag gactatattt cagttataaa aataataaaa
      241 ataataagat taactttgag gcagttttag aggacaaaaa aaacttaatt ttcttattga
      301 gccttatgtt tggaatgtac ttgtatctat gtttgagttt gtcaatatac tatactgttg
      361 gaaatgtatt gattttaaaa ttatatggaa tcaagtctgc cataatagtt ttggtaggta
      421 actatattgc agaaagatat agctttagaa ttactcaaat aaaaggttat gatattaaaa
      481 atcaaataga atatgtagaa agtgtaaaga cagagtatga gattaataaa ttgaatgata
      541 ttgtatatac agatttactg acaggtttct acaatagacc ttttgtgaat caaaaactat
      601 cagaatggac atcaaatcac tacaaattta ccttatgttt tactgattta aatagcttaa
      661 aacctgtaaa tgataaattt ggacaccaat ttggtgataa atacatatcc actactgctc
      721 aaataataaa aaaacttata aatgtagaaa attccttact atttagatat ggtggagatg
      781 aatttttatt ccttttacag aatacaagtt gtgtagaagc agaaaagata atgattaata
      841 taaattatga attatcaaaa ataagtaata ccgacgagta tccttatgct ctttccataa
      901 gctatggatt agttgagtgg gatggaatat ccgatattga aactttaata tcaaaggcag
      961 attctttgat gtatgaaaat aagcttaaaa ataaatctac tttaaactag ctagttcaga
     1021 tattctacaa aatatatatt ataagatagt actaagaatg tcaaaatata tagattttgc
     1081 aaatattgaa tacagtttac taatgaatgc actggatgta agtgttagta aacacctatt
     1141 agatgaacac tttactgttg tttgggctaa tgaccgttat tatgaaatgt tcggctatac
     1201 ctagctaaaa agttaaaaat gaccactgta gccgagggaa tagagactag ttttcaaaaa
     1261 gatttcttgc aagaaataga ctgtgatatg ttacaaggat acgtgttctc tagaccttta
     1321 ccaataaaag actttgaaaa acttatgttt caaaactcct ccaattaaca atataaaatt
     1381 gcttattata agtgatatta ttgtatcaac aaataaagga attgtctcaa aattgatttt
     1441 ttctaatcaa atttttattt tgagacattc tcattttttt gcataagaaa atacccacca
     1501 agctacggtt tttcttaccg ctgttcggtg ggtattagta gtattatgaa atctgaaaac
     1561 tttaagtatt actacttccg ctagcgcaat cacaaaggtc gaaagcttca aagcgaaaat
     1621 aggcttttta ctcatcaaac gtcaccgtac ctgccaaccc gtccaccgtt atcatttgtc
     1681 cgctcttaat agctcgtgtg gcaatgtgtg tagccataac ggctgggatg ccatattcac
     1741 gtgcgacaat gcttgaatgg ctaagaggac caccaatgtc cgttacaatc gcacttgcag
     1801 atgaaaataa tggtgtccat gctggagttg tggtaactgc aaccaaaaca cttccaggtt
     1861 gaaagctttc aaaatctgct ggactattca gtacacaagc tggagccgtc acaacaccag
     1921 tactggtacc aatgcccgtc aacacaattt tcccatcttt ctgcttctgt tgtgcttgtg
     1981 atatagtttt tttgtttttc tctggcaact tggatggtga cacataaccc atgtattttt
     2041 taagttcagc ttttcgaaca ggtattatcc cgttcatatc agatagagac ttgtttttat
     2101 ccaactgctc tataagtacc tccaattccg attttgtgag ccaataaata tcatctaaat
     2161 gtgaaatagc tcctcctcgt atgaatcgtt ctgagatttc ctgaaacata caacgaatca
     2221 gaggatgtcc cattcccatc aaataaatag cattttcacg cataggagag gtttcctgtg
     2281 cccaatggag caacttaaaa aatagttttt tacgcaatcc acctatgtgt tgtaaaatct
     2341 cttcttctgc atgttttcta cgcttttcaa acgtggtctg gcgtaaaaaa ggactttccc
     2401 cttttccttc cacaaatgtt tttacggatt caaaagttgg tgtaagtgtt tcctgcggtg
     2461 tggaatgcgc aaaatcaaac tcataagcgg tacgaccaaa ctctttaaag tacttattga
     2521 ttcgattttt ccattctatc catacttcct gtgaaactcc aacaggcaca actgaagaca
     2581 tgaaatcttc tgctatcttt attgcaggac tgttttgcag ataaaggttg atgctgttat
     2641 tttgctttac ccattctgaa ataccccaca actccttttc cgattgcaga acaatcgtat
     2701 caaacccaag caggaaaacg gaagtatccg ttataccagc acgtcgaact gctccttgaa
     2761 ataattttgt aaataatgtt tcactgatag aagcagcagg caatgtaagc tgaatccttg
     2821 tgaaataaat acatgcggca taaaatattg tctgaatacc ctccataatt tgatgggcgt
     2881 tcatagtatg caggggcttt tcttcccatt gtttaatagc atcctcatat ccttttcgtg
     2941 ccgtttccca gcgtgcaacg ctgttcataa gtgtcctacg taaagagcgt ggggaaaggg
     3001 atttgatagc aatcaaaagt ggatttgatt tagcagaaag ataaacatat ccattaataa
     3061 ccgtatatgc cccgtttttt ggtaataatt ttttcgcact tttaccaaac atatctatcc
     3121 ataaaagctc tgatgcacgg tttacgattt caagaccaag cgtggcgaac aaaggtgtaa
     3181 caggatttgg caaatgttct gccaaacttc cctttgtgta tacaacatcc tgttctggca
     3241 atacccattc tggtggcaga acagtaattg gacgagcctg aacaatgtac aatttatctt
     3301 tttccagtgc ccactctaca tccataggca tttgataata cttctcaatt ttctttccaa
     3361 gctgtatcag ttgcattacc tgattacgag taagagcata tttttttctc aacctttcag
     3421 gaaccatggt ttcttctgtt ccttctgaag tacgaaccgt cataatctct ttatttgcca
     3481 cttcatacga tataattcgt tcggagtcct tatccactac gattgtatcg ggtgtaacta
     3541 agctagaaac caccgcttca ccaagccccc atgcagcgtt aataatcatt tcgctacgtc
     3601 taccattgat tgggtttaac gtaaacataa taccagatga atcggaaaat gcaagctttt
     3661 gtactacaac agcaagtgcg acaatctcgt gctttatatt attcttcaca cgataagcaa
     3721 tagcacgagc tgtccataag gaagcccagc atctctttac agagtcaata actttatctt
     3781 caccttgtat gttaagataa gtttcctgct gacctgcaaa agaagcgtca ggtaaatctt
     3841 cagcagtcgc agacgaacgg acagccaccg atatgttccc taatccagca taagccattt
     3901 taattgcgtc cgacacttcc tgtggcattt ctccattatg gaaaagctcc cctattttct
     3961 tagatacatc ttcaagttgg ctggtattat tggaatcaat accatctagc agtttattaa
     4021 ttcgagactg aatatggttc gtctcaacaa aaatctggta tgaagcagtc gtaacatgaa
     4081 aaccgtctgg cacagggatg cctgctgtca atagttttga taaagacatc ccttttccac
     4141 caacaatttc aatggttgct tgtttatgtt ccagtggcaa gacataataa atcataatca
     4201 ttcacctcca tcattcataa ttccgtgcag aaatatattc attgtttcat ccaacatttt
     4261 ttccgaacta tccaatggtc gtgacgtgta gctgattgat aacatggagt taattaacaa
     4321 acgtgtcaca agagcggtat ccgttttgcg aaagatgcct gtggtcacac cattatcaat
     4381 taccgatttt ataatatctt gatatgcata acgagcatct ttaagtctct ttcgatactc
     4441 ttcttctaaa taatcagatt ctgtatttaa ccacatcagt acagttctat actgctctgg
     4501 aaatctaaga tgattaagca tgatttttct aaggcactgt tgtggtgaag gttcaccatc
     4561 aataatccta tgaacttgtt ggatagtttt ttctatttct ttctcaactg catatacaac
     4621 aatctcgtct ttcgttttga aaaaatcgta tagacttgac tttcccatgt tggctaaaac
     4681 tgcaatttct ctcattgatg ttttttggaa tccattttca gccataagac tcaaagcaac
     4741 agcaactatt ttttctcggc gttctgcttg ttgttcgggt gtaagcacaa ttccttttgg
     4801 catagggcga tacctccttt tagcgaccac tggtcgtttc ttttttattt atcatacagc
     4861 gaccaacggt cacttgtcaa ggttaatttt tttcattgta tatggtactc gagataaaaa
     4921 tgttcatttt agaaattgct ctatttaagt agaaataggc ttcatcatta gaaaacaaga
     4981 ctataaattt gagatattta tcatgttcaa atttcatcaa tatcaaagtt taagatatta
     5041 ataaaaaaag aattactaag aaataacata taaagattca aaaaaggagt tgaacttaaa
     5101 attcaattac aaaaaatcaa atttaagaca actcctttat tctttatctc tactattctt
     5161 tatctctatt tatttattac aactccctaa catttaccac tactgcctta ggtctagtca
     5221 tagcctcgat tgaatactta acaccttgag ttcccatacc agatgccttt acacctaaaa
     5281 atgggaagtg gtctggacct ctttcagtct tattatttat ttgaacagta ccaacttcaa
     5341 gtttatcagc tatataaaat gccttatcaa tatcacttgt aaatactgat gattgaagcc
     5401 catactctga ttgattagca atttcaattg cttgatttat atctttaact cttataattg
     5461 gaagtactgg accaaatggt tcttcccaag caattttcat atcaacattt acattatcta
     5521 acaatgttgg atagaataaa ttattttttc taacattgcc tgttattaac tttgctcctt
     5581 tatgtaatgc atcatcaacc aacccttgaa caaaatcagt tgctttatta tctataagag
     5641 gagtgataac tacttcatcc attggatttc caattgtcaa cttctctacc aatggcttta
     5701 tttttccgac taatttatcc gccacactct cttgtactaa aattctcttt actgccgtac
     5761 atctttgtcc tgaatatgaa tacgctccag atactatatt cttagctgca aaatctaagt
     5821 ctgcatcttc taatactata gccgcatctt ttccaccaag ctccaataat aatggtacca
     5881 ttccagatat tttagatata tgctgaccaa cttcagtact accagtaaag ttaataaaat
     5941 taattccttt atgcgttaca acataatctc ctatctcact acccctacct gtaatagtat
     6001 taagtactcc atctggtatc ccagcttttc tcataatttc taccacatga agtgcgctaa
     6061 tagccccttg tgtagcaggt tttaatacaa ctgcatttcc accaataagt gctggagcaa
     6121 tctttgacat tgataaattt acaggataat taaaaggaga tatagctaaa acagtaccta
     6181 atggaaccct tgaaacataa gacatcttat ttcttgttcc accagggaaa ttatctccac
     6241 taatggcttc accctccata ttttttccca catcagctgt gtatcttaaa aaatctgctg
     6301 ttctctcaac ttctgccctt gcagatttta tgtctttggc tatttcaagt accagtatat
     6361 tagctatctc atctatattt tctaacaata aatcagcagc cttatgaaat atattggctc
     6421 tcttatatac aggcatttca gcccatactt ttatactctc ttttgtgttt tttataacct
     6481 catctacctc atgttttgtc atagattgta ctttcccaac aagagaatta tctattggtg
     6541 agtaaatttc tattggcttt ctcgaattag attctaccca ttttccattt attaaatttt
     6601 tatatacatt ttcttttgtt ttaagttcat taaacatatt tttattcctc tctctgatat
     6661 aactttgtgt atttaaatta tagccattta ttcgttatgt aaacatttct ttttttcata
     6721 aacgtttacc tataaaaaaa ttttaagtta acgtttttct acattcttct attttaataa
     6781 catactcgct ccaaatctat ataggtcaca ctttaatatc aatatactaa tataccaata
     6841 taccaatata ccaatatacc aatataccaa tataaatatt ataaacataa atcacttgac
     6901 aaatttataa gtagacaata ttatatatct atgacttaaa atatttttaa agtcatagat
     6961 atcatatata gatagaaagg attgataaaa atggctaaaa gttttacaga aatagaaaaa
     7021 gacaatataa gaaaaagact aatttcagaa tgtgaaatca actggtctaa atatggatac
     7081 aaaaaaacta atattgatga actttgttca aaatcaggaa ttgcaaaggg ttcattctac
     7141 acattctttg attcaaaaga aaagttattt tttgaagtat taaatggaat ccaaaacaga
     7201 cttatatcat cagtagatga aattttaagt aacatgcctc caaaagaagg ctttgcaaaa
     7261 gccttaaaga tgttgtatcg attatatgat aaaaacccat tcttatattc accaaataat
     7321 actgattaca tcactttatt gaataagata cctaaagaga tgctttcaca acttgaatac
     7381 agcaatgtac aaagttttta tagcttaatt gaaagacata atctcaagtt aaaaatagag
     7441 aaagaaaaag cctttggtgt ttgcaatgcc ctactgtcaa gcctattgct aaaagaagat
     7501 attggatatg actacattga agtatttgat tttatggtag acaatcttgt agaacacata
     7561 cttgagtaat aatttaaaat aaattttcta aacatttctt tataactagg aggagtaata
     7621 tgattgaatt aatacaaaga ctaaatgata ttatttacaa aataaatgat aaactaaata
     7681 tccacacaaa acttgtagac cctagcagtg agctcatgcc actttactct atgttatcta
     7741 taatcgtttc tatatttcta ataatattag gtattaaagt aagaaaaaaa ttccttataa
     7801 taattgctat tatatcaatt attataaata ttttaataat cttagatagg taggtacata
     7861 tatggtaaaa tcctcgaaca cttttaataa aaacttcaac ttgatgatat taggtcaaat
     7921 aatctcattg tttggtgcat caatacttaa atttgcttta tctttataca tacttgatat
     7981 aactggtaaa gcagaaatat ttgctactat actagcagta tcttcaatcc caattatagt
     8041 attctcccct attggtggag ctattgcaga tatattcaac agaagaaact taatggttat
     8101 ttttgatttt tcaagtagtc ttacagtact aatcttagca gtattcttat tcaacaataa
     8161 tggttcaata ttacttgtag gaattattat gaccatatta tcagtcataa gcacaatgta
     8221 tcaaccaact gttcagtcaa gtacacccct tttagttgat aatgagcatt taatgaatgc
     8281 aaatggtatt gtagctggag ttgcatctct tacaaatatt gcaggacctg tattaggagg
     8341 tgtcttgtat ggtgtgattg gaattaatgc aattatagtt ataagttgtg taagtttctt
     8401 tctatctgca attatggaga tatttataca gattcctttt atcaaacaag agcaaaacag
     8461 caacattata aaaactatat ttactgatat aaaggatggt attgttcata tatgtaaaga
     8521 aaatagattt atactaaaaa tacttttttt agctatagca ataaacttat ttttaagctc
     8581 tatgttaata gttggtatcc cctatatagt aaaaatcact atgggagcta gtaacttctt
     8641 atatggtcta gcagaaggag caatttcttt tagttcactg gtagctgctg ttagtattgg
     8701 tattttctca aaacatctaa aaatcactaa tttgcatatt tcctttatta tatgtgcagt
     8761 tatgttcata ccaatggcgg tttcagtata tccatttata ttaaacacag gatttccagt
     8821 tccattttta atctttatag tatcatctat gctaatattt tttacaacga ctcttatctc
     8881 aatatatgtt ataacagtca cacaattaaa aactccaaat gaactcttag gaaaagtaat
     8941 gtcaattctt tttgcaggaa cagcaattgc aatgcccctt ggtcaggtta tgtatggtaa
     9001 actttttgat ttattatcag atagagtgta catcattata ctaggagttg gatttattac
     9061 attacttata gcatttgtat caaagataac attgaggaac gaaaatcttt agatacaaag
     9121 aatttagata taaagattta attttcacta atttctgaat ttaaatgcaa aattgtgtat
     9181 cagtatgttg acgttttaga aattgattga tataatcaat ggaaaataaa ctttataaaa
     9241 attcaaaata ttcagctaga ggagtgataa aaatgagtta catgccaact ttagaacaag
     9301 catgggaaat attaagaaaa tacaataagg aagaatttca tataagacat gctcaaattg
     9361 tatctggagt tatgagatac tatgcaaagg agtacgaccc tgaaagagta gaattttggg
     9421 aaatagttgg acttttacat gatttagatt ttgaaatgta tcctgatgaa cattgtgtta
     9481 aacaaagaga attaatgaca gagcttgatt tagataaatc aataatcgat tctacaataa
     9541 gtcatggata tggattaact ggttcagatg ttaaaccaga gcaatttatg gagaaagtat
     9601 tatttgctgt ggatgaactt actggtttaa ttggtgctgc tgcaataatg cgtccttcaa
     9661 agagcgtttc tgatttagaa ttaaaatctg ttaagaagaa atttaaagat aaatcatttg
     9721 ctgctggctg ttctcgagac gttataagaa gtggtgcaga aatgcttgga tgggaacttg
     9781 ataagcttat ccaaacaact atagaagcta tgagaagctt gattccagag atggcaatat
     9841 agctcctcca tacatatacc atagaagtta catctttaaa gagcatttct ctttttgatg
     9901 caacttcttt ttatattttg tagaataaaa agtttaatat tttaaactca ctatataatc
     9961 tataataaat actataaata atataatgta taatagtcat aaactttcta accttaaaag
    10021 tttctaataa tcaataaaca attctaatat acaaatgtca ttatatgatt taattatata
    10081 tcttcaattt atatattaaa ataaatatat atatattaaa ttcttataca ccaaattttt
    10141 acattaaact tctatgcacc acatttatac atattaaatt cttatatatt aaatttctat
    10201 gcatcacttt tatacatatt aaattcctat atattaaact tttatgcatc acttttatac
    10261 atattaaatt cctatatatt aaacttttat gcatcacttt tatacatatt aaattcttat
    10321 atattaaact tctatacatc acttttatac attaattctt atatattaaa cttctataca
    10381 tcacttttat acattaattc ttatatatta aacttctatg catcactttt atacattaat
    10441 tcttatatat taaatttcta cacatcaaat ttatatacat ttaaatcaca tgattaactg
    10501 ctttcttcac atttctaagt ggaatagcaa ttttaactac aaatttttta tcatcatatt
    10561 caattacaac attaccacca tacttattta cagagttttt tacacttttt attccaagtc
    10621 catgaagaga accttttttg tctgtcaaaa tatctccatt tttagtaata atcttattca
    10681 tcttagtatt ttcaactctt attaaataaa aattttgcat aacatcacct ttaacacaaa
    10741 taactctatt tccactatca attttattac atgcctcaat tgcattgtct aaaatatttg
    10801 aaaatatatg acatatatcc actaattcaa cagcttcaca acaactaaaa tttattccta
    10861 tttttagttc tatatcattc ttatcacaaa cctctttctt ttcacttaat atagcatcta
    10921 atataaaatt accagtatta aataacaagt cattactctg aatttctacc tgcaaattat
    10981 ttaaataaga agtaacatca ataccttttt taatcatagc atttatacac aagatgtgat
    11041 ttttcatatc atgacttagt aatctagttt ttaaatattt cttttctata tcttcataat
    11101 actcattttc atacttcaaa gtatttttaa tcatattatt ttctacaact aaagtattat
    11161 attgctgtaa ttttttagca attaaaacta aagtgatact tgatataagc aatacaacag
    11221 aaatcataac gaattggaaa ttatgtatta agctaccaga ccctggatta aatatgtatt
    11281 caaaaattac aaaaaaagat gctatattag cgactatagg aataactata taaaataatg
    11341 tccttttatt tatttctata ttaagtttta tctttaaggc tctatataaa agcaaagaca
    11401 caatcaaaag tatctttccc aatattatag actcaattct gtatatatct cccgtcccca
    11461 tactactcat gtcatttata gaattaagcc aaactgttaa agatatactc aaagcatctg
    11521 tggcgattag taacatccaa taaattaagg atattaatac agactttata aaccccacat
    11581 catatgagat tttataaaat gcaatagtaa ttatcataga tataattact cttatatttg
    11641 gaggtacatc aaaaaaatat attatgtcag caaaaacaat aatacctacc acacaaaagt
    11701 ttattttttt gttagaaatc cttttctcac ttgtataatc tagcattttc ttacaaagaa
    11761 accattctat cataaaggat atcgcaatga aaatattcca aaataagctt gactttatca
    11821 taatactttc tcctaacgta ttactaaatt atttttttat attttatgta taatttaatt
    11881 atatacgact ctacacgtgt agtaaataga ttgtcaaaat tattccaaat aagtccatat
    11941 ttcttttctt ttttaattat atcactaaat ttgctaaatt gaattaaact ttttattgct
    12001 ttttttaata ataactatat aaatttatct ataactaggt ataaaatata ttatttataa
    12061 agtttttaca ttatttccat aataaaatct tataaatatt acaataaaat atttttttcc
    12121 atgatatacc ttgataaaat ctctgcttct ttaagcagta actttgagtt gaatcattat
    12181 agtgatttat aacatttata gaaatgctgt tatagattta tatttaaaca ctacaaatgg
    12241 aaatttaact attataaaaa acaatcatta gataaaatga ttcttacaac aaaagcattt
    12301 ctattgtaga tttattagta aataataaat ctacaataga aaaaactaga agtacagtat
    12361 cataaaaata taattaactg tacttctaaa ttattgtttt taaaataaat tttcattcat
    12421 taaaaaatac acataaatat ttccagactc cgattcagca aacttatata agttcacttt
    12481 ttatttatca tcaattattt tcatatactt cttttatctc atcttcactt aagtcaaaat
    12541 cattaaattt atttaatatg tcatctaatt taaaaccatt ttttttcaac attataatta
    12601 ttttataatc tttttctttt gcaactctaa ttgctgtctc tctttcaatc tcttctttaa
    12661 aatttctact tttattcatg atataagcac ctcttttcag atttaataaa tattcttcat
    12721 tgctacctaa ttcttttaat ctatcaagtg cttttttaat aatagaatca ttcttagcta
    12781 taactcttac atctaagtta gaaggattac taataagttt tccccatagc ataattctat
    12841 ttactatata gtcagattta tgaatttttg gaagctctat aaaatataat gcagttttac
    12901 tagaataaat atctggatgc ccgtccattg ttaatctcag gcaatttaca taatcttcta
    12961 tgtgattata ttttacatga tttagtatat gtattccaat agtttttcca atttctttat
    13021 actctttacc ttcttctaac tttctaccat gtacacgact aagataatat tcagctcttt
    13081 ccaaataatc gttctcaaaa gctctttgca tctcaatatt tatatgatta ttttcttcat
    13141 cttcagccaa aatatcaagt ttaggtcttt tctctccaat gtaattaatt gttggatcag
    13201 tttcaactct aattattctc tttatttgag tgaacggttt gatattcctg ttagcatatg
    13261 gagcatcttt tagaatatca tttataaaat ttacaagtaa atcatattca ttatttaaag
    13321 tgaacaatga tttaaatacc tcatcatact cgggcttagc atatccatct tcagtcacaa
    13381 cttctccaac attttcatta gtcaaaatct cttttggaat taacgccttg attttatcta
    13441 attcatcatt agaaaaacta cttctactaa gtatatcatt taattttttg gtccattctt
    13501 tatctttttc ttcaattata gttcgcttat attcttttga tgttttaata atcttagatt
    13561 tttcttctac tttttctatc atttcaacac ctctcttttt cctcttttgt atttatcatt
    13621 tcttgaaatt aaactaagtc actacctctt ttaaaagttc ttgctccata aacactttct
    13681 taaactctaa tgtctgtgta tgtacttgac attctctctc tatctaaagt taaataaatt
    13741 aatctatgta tagagggtaa gtccaaaaat aacataaaac actaattaat catttataaa
    13801 gcattaatta atcactgaca atgctgttat tgtcaccaca tagcaccaac atagattctt
    13861 ctattatagg gcaattatct atgaaaaata gactcataag attagaaaat gtacttaaat
    13921 tttagttcat ttaaatattc attttgaaga aagaaattta actttagact aaaaaggaaa
    13981 tatttcaaga ggattaagaa attttcttaa agggataata atttttatga aaatggaaca
    14041 aatatgaaaa taaagttatg atttttacag ccataacctt accaacaagc acttaattat
    14101 cactcaaaaa ataaacgttt atttaaagaa tgcacataaa tatttccatg ttcaaaacac
    14161 ttctatgata tatttattaa taaatctacc atacaaaaaa ctagaggtac attaatcata
    14221 aaaatatgat taactgtacc tctaattata ctcatctttt cataaattta atcactatgc
    14281 atcaacatat caacatattg attaaactta tcttatataa caatatctta gctactaata
    14341 taatatatat tagtcttgaa taatactttc tcttgattca atttcttttg aaatactagc
    14401 tataaattca tctaatttaa tactacctat ttcaccttta tctcttgatc taacagaaac
    14461 attattatca gctacttctt tttcacctac tattagcatg tatggcactt tttcaagctg
    14521 agcttctctt atcttaaatc caattttttc agctctatca tctaattcaa ctcttatacc
    14581 cttatcaaat aactctttct taacttcatt tgcataatcc ataaatttat cagatatagg
    14641 aagtatctta acttgagttg gagataacca aactgggaat ttaccagcat aatgctctat
    14701 taatatacct ataaatcttt ctatactacc aaaagcaacc ctatgaatca taactggtct
    14761 atgcttttca ccatcttgac caatataagt attatcaaat tgtcttggaa gctgcatatc
    14821 taattggata gtaccacatt gccaagttct tcctaaacaa tcttttagat ggaagtctat
    14881 cttaggacca tagaatgctc catcaccctc attaatagta tatggtagac ctaactcttc
    14941 taaagcttct cttaatccat tttctgctgc ttcccactct tcgtcgcttc ccatagagtt
    15001 ctctggtctt gtagataatt ctaaattata ttcaaatcca aaagttttgt atataccatc
    15061 tattaagtta gctactcctt ttatttcgtc cttaatttgc tctggtaaca tgaatatatg
    15121 tgaatcgtct tgagtaaatg ctctaactct cattaatcct tgtaatgcac cagataactc
    15181 atgtctatga actctaccaa gctctgcaac tctcattggg aaatctctat atgaatgtag
    15241 ttgagagtta taataaatta atccaccagg acagttcata ggttttatag cataatcctc
    15301 atcatctatt ttaactgtat acatattttc tttgtaatga taccagtgtc ctgaagtctc
    15361 ccataatttt ctatttaata tgattggaga ttctatctca atatatccag cttttctgtg
    15421 tatttctctc cagaatttta ataattcatt tttaagttcc ataccttttg gtaaaaacat
    15481 agggaatcct ggaccttctt caggtatcat aaataatcct aattctttac ctaattttct
    15541 gtggtctctc tttttagctt cttctagtaa atgtaagtac tcttctaagt ctttgttttt
    15601 ctcaaaagaa gttccatata ttctttgaag catcttatta ttttcgtcac cacgccaata
    15661 tgcacctgct acactttgta atttaacagc ttttaccttt ttagtagatg gtaaatgtgg
    15721 tcctctacat aaatcagtaa aatcaccttg cttgtagaaa gatattattt cactttcagg
    15781 taaatcagat ataagttcta ccttatagtc ttctccttgt tctttcataa gctctaaagc
    15841 ttcatttcta ggaagttcaa atctttctat ttttaaatct tctttagcta tttttttcat
    15901 ttcagcttct attttctcta ggtcctctgg aactaatcta tggtctaaat ctatatcata
    15961 gtagaatcca ttttctatac ttggtcctat agcaagcttt gcttctgggt aaagtctttt
    16021 tatagcttga gctaatatat gtgctgatgt atgtctaaaa acttccttac cttctttatc
    16081 ttcaaactta aataaattca agtcacaatc agtatctata atgtggtcca gacctacaac
    16141 ctctccgttc acagacgctg ctaccacatt tctagctaat ccttcactaa tggatttagc
    16201 tacatccata acagaaatag cattttcaaa ttcttttatt gagccatctt ttaaagcaac
    16261 tttaatcatt gttttttcct ccttattgaa ataattttta gattttttgt aataaaaaat
    16321 cgccccaaat atgtttggga cgatattaat tcgcggttcc acccaagttg gcgtatacaa
    16381 gtatatacaa ccctcttgat gactataagg tcgtcacccg agcactttca cgtatagtac
    16441 aaaacaaata ctgctaataa gctcagctcc aaggtagttt tcaaatagac ctattacatg
    16501 ggctctcagc catagaccca aattctctga gaatggtttc tactctactc ttcctcttca
    16561 acactatgat ttttaatata ttttcattat aacagatagt tatacatcaa tcaacattaa
    16621 tgtaatatat taattaccca ttatttttca tctcaatcag ctgtaaacca atattcttat
    16681 atttttatat taaattaatc tcttgattta tagtgatatt ataatatttt cataaattta
    16741 aaatttttaa aacgtatcca catgcatgat agatatgact agataaatac taaaactaat
    16801 ttttattaaa actaacttct aatttttgta ctctttttag gttttgtata cttaaataca
    16861 atcaatactt aatatagtta ataagtagta cagtaaatac ttaaatacta ttaataagta
    16921 acacaatcaa ataaataaat acaattaata tctaaatgct attaataagt aattcactca
    16981 aataggtaaa tataattagt acttaaataa atgctacttc tcatatattt aaataaacat
    17041 agtaattaac ccttgagcta tacctattaa aaaccctaag acaagcccca aaaactctat
    17101 atgttttaat tctttcttag ctattcttat tattatctct tccaattcat ataaatctag
    17161 ttcattaatc ttatcttcga ccattttttg tatatctata cgttcatttg ctttatttat
    17221 tatattttta ctcaattcat ctatactttg cttaacttca gactcaatta tctctcctag
    17281 ataatcttgt atcatgtttt ttataccact cgggataaat gaaactttct catgtattat
    17341 aatttttacc cttgctttta tgtatcttac aacttcttcc ttatcttcgt cagtaatgat
    17401 atttgcaagt atttcgtcca tagaaagaaa ttcttcttga attatttctc ctacatttgc
    17461 tgctatttct gctcttctct ttggtataag acctactatt tctatattta aaataggtat
    17521 tttaataggc tctattggtc taaatatcag tcttatagca actacattcg taacataacc
    17581 tataaatcca ccaataacag ctaatatcag tatcctaatt aaattatcca ttataaaatt
    17641 actccttatc aattgtatat ttgccagcta tattgtatta atcaagtaga tattctttat
//
LOCUS       DAEPKC010000082        17621 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.082, whole genome shotgun sequence.
ACCESSION   DAEPKC010000082 DAEPKC010000000
VERSION     DAEPKC010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17621)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17621)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17621
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.082"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(467..991)
                     /locus_tag="KR294_002784"
     CDS             complement(467..991)
                     /locus_tag="KR294_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBH0240848.1"
                     /translation="MENKNPIVTIEMENGKEIKIELYPNIAPNTVKNFVSLVNEGYYN
                     GIIFHRVIPGFMIQGGCPNGTGMGGPGHSIKGEFSGNGFTNNLKHERGVISMARTMAP
                     NSAGSQFFIMHKNSPHLDGQYAGFGRVIEGMDTVDEIASVRTDSADKPQTPQIMKSVT
                     VETFGIDYSDVEKN"
     gene            complement(1056..1808)
                     /locus_tag="KR294_002785"
     CDS             complement(1056..1808)
                     /locus_tag="KR294_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HBH0240849.1"
                     /translation="MKLGLCLEGGGAKGAYQAGVVKALYDGGINKFYSISGTSIGAIN
                     GYYLYTGNVDNLEKMWTNIKDIQNGNVKIVNNTVDNSPAIDNLRELDDSNIEEMNFYV
                     NYVEVDNKVVSEKIVDVSKMPRNEAIISISYSGLLPSNPNATLGFKEQFVKDVQEGIY
                     DGFKLDGGLIRSALIEPLIGDNVDKIILISTKYNYELPEDIKKVYDEDKIIVVRPNTQ
                     FAPKDTLNFDDEFCKTIYQEGYEIGKNILDRL"
     gene            complement(1839..3137)
                     /locus_tag="KR294_002786"
     CDS             complement(1839..3137)
                     /locus_tag="KR294_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M18 family aminopeptidase"
                     /protein_id="HBH0240850.1"
                     /translation="MDSINFAKNLIDFIYDSPSSFHAVKSTKEILDKNGFEELVLNQR
                     WNLRVGGKYYVTKNLSAIVAFVVNSEDIERDGFRIIGSHSDSPTFSIKPNAEIEAEKS
                     YLKLNTECYGGAILSTWLDRPLGIAGRVVLKGDSILKPNERLIDFKKPICIIPNLAIH
                     LNRSINDGHSYNKQKDMLPLVGMLNDTLEKDNFLIKQIASNLDVNMDDIIDFDLFLYE
                     FEKGSLIGANDEFISIGRQDNLAMVHASLNALVNTKGQHGVNVMAVFDNEEVGSSTKQ
                     GADSNMLLNILERICISMGKDREGFFESIYSSFMISSDLAHAIHPNIPEKHDPTNKPI
                     MGKGPVIKINASQAYTSDGYSIAIYKNICREANVEYQEFVNRSDERGGSTIGPISSTH
                     IDIPSVDVGSPILAMHSIRELGNVEDHYSIYKTFSKFFEI"
     gene            complement(3154..5418)
                     /locus_tag="KR294_002787"
     CDS             complement(3154..5418)
                     /locus_tag="KR294_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3553 domain-containing protein"
                     /protein_id="HBH0240851.1"
                     /translation="MNLDTLNPAQREAVEKTEGPVLILAGAGSGKTKVLTTRIAYLIE
                     DKGVQAPNILAITFTNKAANEMRERVEQNIGPETKDMWISTFHSCCVRILRKDINKIG
                     YNRSFVIYDSADQVTLVKDCLKELNLSDKVFEPKAVISAISGAKDKLYTPKQFKDINM
                     ADNRMVKIADIYALYQDRLKRNSALDFDDLILKTVELFKANDEVLAYYRSRFRYIMVD
                     EYQDTSKAQYELIKLLAREHQNICVVGDDDQSIYGWRGADIRNILEFEKDYDNVHVVK
                     LEQNYRSTQVILDAANKVISNNIERKRKKLWSEKKEGELIKIQLTGSEIEEADFIADS
                     IAQIARKENRPYKDFAVLYRANAQARPVEDALNRSQIPYNIYGGTKFYERKEIKDLLA
                     YLRVIQNPQDDISIKRIINVPRRGIGLRTIEKIEDRANLKQESIYSVLIDIETNSDIS
                     TKARASISGFVDIIGTLRTIKEVYPVSKLIEKVLDTTGYMDELVEIRNKNEKDLTGKG
                     EEAQDRIDNLREFISIALEFESSNDDTYENKDLETFLTSIALTSESNDEEDNDRVSLM
                     TIHTSKGLEFPVVFLTGMEEGLFPISRAIKSMSDSQIEEERRLCYVGITRAKEELYMS
                     LTEKRTLYGKTNVAIASRFMEELPEECIERLYKVKKELSYSKASYNMLDKYTKKYMST
                     ISKSKVADKVNATIKDSNKETNPDDIKLGSKVHHPKFGVGTVVSIIGTDVTIAFDQQG
                     IKKINKEYTTLNIL"
     gene            complement(5673..6491)
                     /locus_tag="KR294_002788"
     CDS             complement(5673..6491)
                     /locus_tag="KR294_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HBH0240852.1"
                     /translation="MFKINNLTYQYEKNTNALLNINMDFSKGNVIGIIGSNGSGKSTL
                     FMNLMGILKPTSGEILFKEEKLKYDKRSLYNLRKNVGIVFQDPEKQIFYSKVYDDIAF
                     AMRNIGMDEKTIKERINKALVAVNGIDFIDRPVHFLSYGQKKRVAIASVIAMENEIVL
                     LDEPTAGLDPVSTRSIVDIIKGLNKNNIKIVISSHDMNLMYEICDYIYVLDKGILIDE
                     GKAENVFINENNIIQAGLESPWLVKVHRNMNLPLFKKEEDLYKYWKERELNTNK"
     gene            complement(6484..7182)
                     /gene="cbiQ"
                     /locus_tag="KR294_002789"
     CDS             complement(6484..7182)
                     /gene="cbiQ"
                     /locus_tag="KR294_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ECF transporter T component CbiQ"
                     /protein_id="HBH0240853.1"
                     /translation="MLIIDKYAYTNRLSKVNPNKKVAIGVIFLIASMVIQNIFILSGI
                     MILMSILVVCVAGIDLKNYLKLLRIPMYFLFLSIGITLVNISFNKADLLYSFEFFSFN
                     VGISKASIDMSIHVLFRAMSCLTCVYFCILTTPFNQLIFFFKKLHLPDTFVELSMLIY
                     RFIFIFLEEFSEIYKSQELRFGYINLKTSYKSLGILGSMLYKRLMTRYDDMCISLDIK
                     LYDGKFHIVGDNDV"
     gene            complement(7185..7463)
                     /locus_tag="KR294_002790"
     CDS             complement(7185..7463)
                     /locus_tag="KR294_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     substrate-binding protein"
                     /protein_id="HBH0240854.1"
                     /translation="MSAKTKTNILLLLLVVALIIFPLLVNSGAEYGGADGQAESEITK
                     INPNYKPWFSSPYEPPSGEIESLLFSAQAALGAGVIGYILGLQKGKRS"
     gene            complement(7453..8205)
                     /locus_tag="KR294_002791"
     CDS             complement(7453..8205)
                     /locus_tag="KR294_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006440549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter permease"
                     /protein_id="HBH0240855.1"
                     /translation="MKQNIKLGVIAALMLIILTPVTSNAMHIMEGYLPVKWSIAWGVI
                     FIPFFLFGLKSIGKIVKQDPKKKVLLALCGAFVFVLSALKIPSVTGSCSHPTGVGLGA
                     IMFGPSVMFVLGTIVLIFQALLLAHGGITTLGANAFSMAIIGPIVSFLIFKALKKKDG
                     NNAIPVFLAAAIGDLATYTITSIQLALAFPDPSGGVMASAIKFLGIFFMTQIPIAIAE
                     GILTVIVYNLITENGEKSILENNDKGVKANEC"
     regulatory      complement(8387..8579)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            complement(8711..10483)
                     /locus_tag="KR294_002792"
     CDS             complement(8711..10483)
                     /locus_tag="KR294_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitric oxide reductase activation-like protein"
                     /protein_id="HBH0240856.1"
                     /translation="MKWIYDDYEFENRANNLSWTIAGDYNESIDISEKDYSSKEIGLY
                     FAIIAGARRKYVDWDIVKKYLTNRIRKGYNKDIILGLIQVILNTIVEEKVIKDRPGIE
                     DIRRNAYKDIVSRFTKIHNDNIMDKIKYTFVLYSMDKHPALDSMTRRIVNDIRNIDTN
                     QDIMEILKALDVIYLTYFEYILNGEENSLIDENNVESVEVNFDTFADFMYEELYSDEE
                     ENIIESDIDSISSSMLVEGVGDFDDSKCSNSADRVIYVDEDTANKIYSKIEHYYGKTY
                     LSKGEIKKIETQNCRNVHEGCRIHFTDGVLRSECNNVFQLKYVTRQKENNLGKFREHA
                     RMYRQQIKRLKESLSRILIEENAKSRVYSDCGTILANRAWRVGRSNNNKIFYKDIENE
                     KGKYVIDILLDASGSQSRNQGNVAIQAYIIANALTEVGIPNRVMGFSSFLDYTILKRF
                     KDYDDSIKNSENIFEYFCAGNNRDGLAIKSICSGLINRDEENKILIVLSDGRPNDVKI
                     GKSSERTLRGEKAYRGIVGLRDTANEVRKARKQNILVLGVFTGKESELEAERLIYGND
                     FIYSRDITRFSDVVSMYLKKIIRN"
     gene            complement(10497..11426)
                     /locus_tag="KR294_002793"
     CDS             complement(10497..11426)
                     /locus_tag="KR294_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBH0240857.1"
                     /translation="MDIIDNLRVQGVDEKLIEDVLYFRNYYGLEKDLEYRVTKSKTYF
                     YGKDILSMCIAAILEEENILLSGPKATGKNLLADNLGEIFNRPQWNTSFHINTDSSTL
                     IGTDTFIDNEVKLRRGSVYECAINGGFGVFDEINMAKNDAIVVVHSALDYRRIIDVPG
                     YERVNLHPATRFIGTMNYEYAGTKELNEALVSRFMVIDIPPIEEDKLMMILKNEFSDA
                     DEEKLIHFAGIFLDLQLKSQNGEISSKAIDLRGLMASLKTIRRGLKPTLAINMGLTGK
                     TFDVYEKEMVGDVIKTRIPNKWESIDVFPISHI"
     gene            11655..11843
                     /locus_tag="KR294_002794"
     CDS             11655..11843
                     /locus_tag="KR294_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH0240858.1"
                     /translation="MEYMSCPEVAKKWGISERRVQKLCEESRIPGVSKLGYMWLIPKN
                     AEKPVDGRTKRRKEVQYE"
     gene            11836..12537
                     /locus_tag="KR294_002795"
     CDS             11836..12537
                     /locus_tag="KR294_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0240859.1"
                     /translation="MNSVLIIDDDKELCALMKKCVEQENLSAITAHGGAEGLHLVDKN
                     RHTLSLVILDIMMPDIDGFQVLKKIRETSNIPVIMLTAKNDEDDKVSGLRLGADDYLT
                     KPFSINELMARVNSLIRRYTMLNPAFITDTDFIIINGMIIDKTNRIVSVNNIPVQLTS
                     KEFDLLAFLASNKGRVFTKKQIYTQVWEEEYAFDDSNIMSFISKLRKKIEPDPNHPFY
                     ILTVRGVGYRFNKEA"
     gene            12539..13462
                     /locus_tag="KR294_002796"
     CDS             12539..13462
                     /locus_tag="KR294_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH0240860.1"
                     /translation="MNTSVYLLLILALSLIIIAYLVSVLLRVRIQLTLIKDALEDIKN
                     GNLNRRILTDENDITKQICYDINEIAINSQFQLIQQKQSEQAYKQLMTSLSHDVKTPL
                     ASLVGYLEAVESKIVVGEEKDEYIHVASNKAHYLKNFVENLFEWVKLDSKEQVFHFDI
                     FDLNELSRNIISDWIPVLESSHFEYEFDIPEIEYFLRIDANAYTRIINNLLQNIITHS
                     SGNKMTLRIFENKEQAQIIITDNGKGISSDNLPHIFERLYQCDHSRASKGNGLGLAIA
                     KELINAHKGNITANSTPGMGTEFTILLPKAL"
     gene            13619..14542
                     /locus_tag="KR294_002797"
     CDS             13619..14542
                     /locus_tag="KR294_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019639192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0240861.1"
                     /translation="MNDFVIETKQLTKIYGNQTVVDKVNLHVKKGRIYGLLGRNGAGK
                     TTIMKMILGLTSITYGEVDVFGENIKGREKQVYPRIGAIIETPGFYPNLTGTENLEIF
                     AKLRGTAAPNSVKRALEIVGLPYKNKKLFSKYSLGMKQRLGIANAILHDPELLVLDEP
                     TNGLDPIGIAEMRKFIRDLSVEHGKTILISSHILSEISLLADDIGIIDHGVLLEESSM
                     SELEKKNSKYILLQVSDIPKTSLILERQFNTKDYSVQDDYTLHLYNTNLDMGEINKAL
                     VMQNVTVISSQLCNDTLEDYFKKITGGEGIA"
     gene            14535..15272
                     /locus_tag="KR294_002798"
     CDS             14535..15272
                     /locus_tag="KR294_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0240862.1"
                     /translation="MLKLIQTEFLKLRRRKLIWLMLLSALIMPFFALLYFNYFGKTGV
                     EPIKFYKWSAFGYTLWIILPVVLGIFCTMLIHEENQYDMLKQLWIVPISKMGYFFSKF
                     FVVLIYSICFMLITAVASVLFSVLSGYVVFSWASILYLLKKCLEIGVITAFVMLPILA
                     IATSQKGYILPICITLVYAFSGFVIMTINMYLHPLSSMGVIIMRNKDIPGLIFSQEIN
                     VPLAFLCICIWSIVSVLFANIALGRRK"
     gene            15283..16056
                     /locus_tag="KR294_002799"
     CDS             15283..16056
                     /locus_tag="KR294_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0240863.1"
                     /translation="MWKLLWAECQKIRRSKIVWITVFASIMIAVIVFAGGQDVYNDPD
                     LHYGLKSVYDGSRYIDNAGWYMDAVQPWSTFFVLPAVIALLGSYIICREEEEDTIKSL
                     RLIPINETNLTIAKMIITFIFSILLYLLLFTITFLTESVLHFSDLSTKLVLSCMKEYF
                     LDGIGVFFAISPIIALVSRMKKGYWLALVFTEVYSIAGLFAGMSNVLQTFFPIAAIFN
                     ISGYYITTGEKIMGSIMSLLLCACLSAFILKGLKHNEKN"
     gene            complement(16597..17205)
                     /locus_tag="KR294_002800"
     CDS             complement(16597..17205)
                     /locus_tag="KR294_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HBH0240864.1"
                     /translation="MSVINSFILQYGLISVFVLIMIEYACFPLPSEVVLPLCGAIAAR
                     NHFGFLTILILSIIAGILGSIFCYTVGNWGGKSIINKIIEICPKAKKGIFASQDYFNK
                     YSSISVCVCRLIPLCRTYISFIAGIAGQNIITFVISSIVGITIWNTSLISIGYIFSES
                     WVRIMSHYNDYKFLVLIIPISIIFIGFVIKSFIHKKHHKIRL"
     gene            complement(17383..17499)
                     /gene="rrf"
                     /locus_tag="KR294_002801"
     rRNA            complement(17383..17499)
                     /gene="rrf"
                     /locus_tag="KR294_002801"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         5719 a         3030 c         2202 g         6670 t
ORIGIN      
        1 aactaaacca gtctttctaa aatattaagc acttttttct tattatgttt tttaggattt
       61 attgtctata ttattgtaaa ccaaagttat aaaattgtaa atagaatata ttaccataac
      121 aatatttttt tataagtaaa aattataaaa aactttattt ttgttaaatg gaataaataa
      181 aataagttta aaaaatactg aaataagtgt tttccacata ttttatatat ttatttaata
      241 cattattatt taaaaataaa tatataaaca atcataataa aattttttta ataaaacttt
      301 attttttagt taaaatcata caatatatag atttccacaa tacaaataaa ttaaaaagtg
      361 aaatgtattt gtctaaaaac ataataacat ttcactttat cctcattttt aagtaatata
      421 tatttttaat ttttatttat aactaaatct agtttttata taaattttag tttttttcta
      481 catctgagta atctattcca aaagtttcta cagtaacaga tttcataatt tgtggagttt
      541 gtggcttatc agctgaatct gttctaactg atgctatttc atcaactgta tccatacctt
      601 ctatcactct accaaaacct gcatactgac catctaagtg tggtgagttt ttatgcatta
      661 tgaaaaattg agaaccagct gaattaggtg ccatagttct agccattgat atgactcctc
      721 tttcatgttt taaattgtta gtaaatccat taccactaaa ttcacctttt attgagtgac
      781 ctggaccacc cattcctgta ccatttgggc atcctccttg tatcataaat cctggtatta
      841 ctctatgaaa tattattcca ttgtaatatc cttcatttac taatgataca aagtttttaa
      901 ctgtatttgg agctatattt ggatataact caattttgat ttcttttcca ttttccattt
      961 ctatagttac tataggattt ttattttcca taatttatta ccttcctttt cattagttaa
     1021 attacataat tacatttatt atattatact ctaaattaaa gtctatcaag tatatttttt
     1081 cctatttcat atccttcttg ataaatagtt ttacaaaact catcatcaaa gttaagcgtg
     1141 tctttaggag caaattgagt attaggtcta actactatta ttttatcttc atcatatact
     1201 tttttaatat cttctggcaa ctcataatta tattttgtgg atattaaaat aattttatcc
     1261 acattatccc caattaatgg ttcaattaat gcactcctaa ttaaacctcc atctaatttg
     1321 aaaccatcat aaattccttc ttgcacatct ttcacaaatt gttctttaaa tccaagagtt
     1381 gcgtttggat ttgatggtaa caacccactg tatgaaatgc tgataatggc ttcattacga
     1441 ggcatttttg atacatcaac aatcttttct gatactactt tattatcaac ttcaacataa
     1501 ttaacataaa agttcatttc ttctatatta ctatcatcta gttcccttag gttgtctata
     1561 gcaggagaat tatccacagt attatttact atttttacat ttccattctg gatatctttt
     1621 atatttgtcc acattttctc caagttatca acattccctg tgtacaaata atatccattt
     1681 attgctccta ttgatgtccc tgaaatcgaa taaaatttat ttattcctcc atcatacaag
     1741 gctttaacta ctcctgcttg ataagcccct tttgctcctc caccttctaa acataatcct
     1801 aatttcatag tctcatctcc aaattgttta tcttatattt atatttcaaa aaacttacta
     1861 aatgttttat atatactata gtggtcctca acatttccta attctcttat agaatgcatt
     1921 gctaaaattg gacttcccac atccacagat ggtatatcta tatgagtaga agatattgga
     1981 cctatagtac ttcctcctct ttcatctgac ctattaacaa attcttgata ctcaacatta
     2041 gcttctctac atatattttt ataaatagct atagaatatc catcactagt atacgcctga
     2101 ctagcattta tctttataac cggacctttt cccattattg gtttattagt tgggtcatgc
     2161 ttttctggaa tgtttggatg aatagcatga gctaaatctg atgatatcat aaaagatgaa
     2221 taaatagact caaagaatcc ctctctatcc ttacccattg atatacaaat tctctccaat
     2281 atatttaaca acatgtttga atctgcacct tgtttagtag agctaccaac ttcttcattg
     2341 tcaaatacag ccattacatt tacaccatgt tgacctttag tattaacaag agcattcaaa
     2401 ctagcatgta ccattgcaag attatcttgt ctcccaatag atataaattc atcattagcc
     2461 cctattaaac ttcctttttc aaattcatat aaaaataaat caaaatctat aatatcgtcc
     2521 atatttacat ctaagttaga tgctatttgc tttataagaa aattatcttt ttctaatgta
     2581 tcatttaaca tcccaactaa aggtaacata tctttttgct tattatatga atgaccatca
     2641 tttatacttc tatttaaatg tattgctaga tttggtatta tacaaattgg ctttttaaag
     2701 tctataagcc tttcatttgg ttttaatata ctatcacctt ttaaaactac tctaccagct
     2761 atcccaagag gtctatccaa ccatgtactt aatattgctc ctccatagca ttctgtattt
     2821 aacttcaaat aagatttttc agcttctatt tctgcatttg gtttaatact aaatgtagga
     2881 gaatctgaat gagagcctat tattctaaat ccatctcttt ctatatcttc tgaatttact
     2941 acaaaagcta ctatagctga taaattctta gtaacataat actttccacc aactcttaga
     3001 ttccatcttt gattcaaaac taattcttca aatccatttt tatctaagat ttccttagta
     3061 ctcttgactg catgaaaaga cgacggacta tcatatatga agtctattaa gtttttagca
     3121 aagtttatac tatccattcc tcatttacct ccattataaa atatttagtg ttgtatattc
     3181 tttatttatt tttttaattc cctgttggtc aaaagctata gtaacatctg taccaattat
     3241 agaaaccact gtcccaaccc caaatttagg atgatgtacc ttagaaccaa gttttatatc
     3301 atctggatta gtttctttat tagaatcttt tattgtagca ttaactttat ctgcaacttt
     3361 agatttgctt atagtactca tatacttttt agtatattta tctaacatat tataacttgc
     3421 tttagaatag cttagttctt tttttacttt gtacaatctt tctatacatt cttctggcag
     3481 ttcttccata aatcttgaag ctattgcaac atttgtttta ccatataatg ttctcttctc
     3541 tgtcaatgac atatatagct cttctttagc tctagttata ccaacataac aaagtcttct
     3601 ctcttcttct atttgtgaat cactcataga ttttatagct cttgatatag gaaataaccc
     3661 ttcttccata cctgttaaaa acacaacagg gaactctaaa cctttagatg tatgaattgt
     3721 cataagcgaa accctatcat tgtcttcttc atcatttgat tcagatgtaa gtgctatact
     3781 tgttaggaat gtctctaagt ctttattttc ataagtatca tcattactac tttcaaactc
     3841 caaagctata gaaataaatt ctctcaaatt atcaattctg tcttgagctt cttcaccttt
     3901 gcctgttaaa tctttttcat ttttatttct tatctctaca agctcgtcca tatatcctgt
     3961 agtgtccaag actttttcta taagtttgct aacaggataa acttctttta tagttctaag
     4021 agtccctata atatcaacaa atccacttat acttgccctt gccttagtag atatatctga
     4081 atttgtttct atatcaatta atactgagta tatactttcc tgttttaagt tagctctatc
     4141 ttcaattttt tctatggttc taagccctat acctcttcta ggaacattta taatcctttt
     4201 tatagatata tcatcttgtg gattttgaat aactcttaaa tacgccaaca aatcctttat
     4261 ttcttttctc tcatagaatt ttgtaccacc atatatattg tatggaattt gacttctatt
     4321 taaagcgtcc tctacaggtc ttgcctgtgc atttgctcta taaagtactg caaaatcctt
     4381 ataaggtcta ttttcttttc tagctatttg tgcaattgaa tcagcaatga aatcagcctc
     4441 ttctatttca ctaccagtta attgtatctt tataagttct ccttcttttt tttcactcca
     4501 aagctttttt ctttttcttt ctatattatt agatataact ttattagctg catctaatat
     4561 cacttgtgta gacctataat tttgttccaa ctttacaaca tgtacattgt cataatcttt
     4621 ctcaaattca agtatgtttc ttatatctgc acctctccat ccataaatac tttggtcatc
     4681 atctccaaca acacaaatat tttgatgttc tcttgctaat aattttatca attcatattg
     4741 agctttactt gtatcttggt actcatctac cattatgtat ctaaatctac ttctgtaata
     4801 tgctaacact tcatcattag ccttgaaaag ttctacagtt ttaagtatta aatcatcaaa
     4861 gtcaagtgca ctatttcttt ttaaacggtc ttgatatagc gcataaatat ctgcaatctt
     4921 aaccattcta ttatctgcca tattgatatc tttaaactgc tttggagtat aaagtttatc
     4981 ttttgctcct gaaattgcac ttataactgc ttttggttca aacactttat cacttaaatt
     5041 taattctttt agacagtctt taaccaatgt aacttggtct gctgaatcat aaattacaaa
     5101 acttctattg taaccaatct tatttatatc ttttcttagt atacgaacac agcaagaatg
     5161 gaatgtactt atccacatat ccttagtttc aggacctata ttttgttcaa ctctctctct
     5221 catttcattt gcagctttgt ttgtaaatgt tatagctaat atatttggtg cttgtacacc
     5281 tttatcttct ataagatatg ctattcttgt tgttaatacc ttagttttac ctgaaccagc
     5341 accagccagt ataagtactg gaccttcagt cttttctact gcttctcttt gagcaggatt
     5401 taatgtatct aaattcatat ttctcctcct gttaacagcc ataaatatat tttaatctaa
     5461 aatatgaatt acttcaaatt ataattatgt attatattaa tagattattt ccaatatatt
     5521 acaattaaat aacatttttc catataattt atttcattgt ttaataaaaa aaataacctt
     5581 atgatttggg gaatcataag gcacctttaa ggggtctagg ttaagggtta ttatatataa
     5641 atctattttt ttaaaatagg tttagggctt aattatttat ttgtattaag ttctctttcc
     5701 ttccaatact tatacaaatc ttcttctttc ttaaataagg gtaaattcat atttctatgt
     5761 acttttacta accatgggga ttctaggcca gcttgtataa tattattttc atttataaac
     5821 acattttctg cttttccttc atcaatcaaa atccccttat ccaatacata tatgtaatca
     5881 catatttcat acattaaatt catatcatga ctggatatta ctatttttat attattttta
     5941 tttaatccct ttattatatc tacaatagac ctagtactta ctgggtctaa accagctgta
     6001 ggttcatcaa gtaatacaat ttcattttcc attgctataa ctgatgctat tgccactctt
     6061 tttttctgtc catagctaag aaaatgtact ggcctgtcta taaaatctat tccattaaca
     6121 gctactagag ctttgtttat tctctcttta attgtttttt catccatacc aatgtttctc
     6181 attgcaaagg ctatatcatc atatactttt gaataaaaaa tttgtttttc tgggtcttgg
     6241 aacacaatac ctacattttt tctaaggttg tataaacttc tcttatcata ttttaacttt
     6301 tcttctttaa aaagaatttc tccagatgta ggctttaata tacccattaa attcataaat
     6361 aatgttgatt ttcctgaacc atttgaacct attataccta taacatttcc ctttgaaaaa
     6421 tccatattaa tgtttaatag tgcattggta tttttttcat attgatacgt taaattattt
     6481 attttaaaca tcattatccc ctactatgtg aaatttacca tcatacaatt ttatgtctaa
     6541 tgatatacac atatcatcat accttgtcat aagtcttttg tacagcatac ttccaagaat
     6601 acctaaggat ttatatgaag tttttaaatt tatatatcca aatcttagct cttgtgactt
     6661 gtatatttct gaaaattctt ctaaaaatat gaatataaac ctatatatta acattgataa
     6721 ctcgacaaaa gtgtcaggta aatgaagttt tttaaaaaag aatattaatt gattaaaagg
     6781 tgttgtaagt atacaaaaat acacacaagt caaacaagac atcgctctaa ataacacatg
     6841 aatagacatg tcaatagacg cctttgatat tcctacatta aaactaaaaa attcaaaact
     6901 atataataaa tctgctttat taaaagatat atttacaaga gttattccta tactaagaaa
     6961 taaaaagtac attggtattc taagtaattt taaataattt tttaaatcta ttccagccac
     7021 acaaacaacc aaaatactca ttaaaatcat aattccactt aaaataaata tattttgtat
     7081 taccatagaa gcaatcagaa aaattactcc tatggctact tttttgtttg gatttacttt
     7141 actcaatcta tttgtatatg catatttatc aattataagc atgattaact tctctttcct
     7201 ttttgaagac ctaatatgta tcctattaca ccagccccta aagctgcttg tgcagagaat
     7261 aataaacttt ctatttctcc acttggtggc tcatatggac tgctaaacca tggtttgtaa
     7321 tttggattta tcttagtaat ttcactttca gcttgaccat ctgctcctcc atattcagca
     7381 cctgagttga caagtaatgg gaatataata agagctacta ctaataaaag taataatatg
     7441 ttagtttttg ttttagcact cattagcttt aactccttta tcattatttt ctagtatgct
     7501 tttttctccg ttttctgtaa ttaaattata tacaattaca gtaagtatac cttctgctat
     7561 tgctattggt atttgagtca taaagaaaat tcctaaaaat ttaattgctg aagccattac
     7621 cccacctgat gggtctggga aagccagtgc taattgtatt gaagttattg tatatgtggc
     7681 taagtctcct attgctgctg caagaaatac tggaatagca ttatttccat cttttttctt
     7741 taaagcctta aatattagga atgatacgat tggccctatt atcgccattg aaaaagcatt
     7801 agctcctaaa gtagttattc ctccatgtgc taataacaat gcttggaata ttaaaactat
     7861 agttccaaga acaaacatta cgcttggtcc aaacattatt gctccaagac ctacaccagt
     7921 aggatgtgaa caacttcctg ttactgaagg tatttttagt gctgataata caaacacaaa
     7981 tgctccacat aaagctaata atactttctt tttagggtct tgctttacta ttttacctat
     8041 tgattttaat ccgaataaga aaaatggtat aaatataact ccccatgcta tagaccattt
     8101 tactggtaag taaccttcca ttatatgcat tgcatttgat gtaactggag ttaaaatgat
     8161 taacataagt gcagctataa cccctaattt aatattctgt ttcatcttag tatccctctc
     8221 tccctttcta ataattaaaa cataataata catgtctgat ttatttaata aaataaaaaa
     8281 gcctaactcg atggttaggc ttctaatttt ccacaatcta aatacaaaca cataaaacaa
     8341 acatatctgt ataattatta taagaaactt tctccatccc cgaagaaatt actttaatat
     8401 tttaggcagg tctcctgact tagcttcatc ctactcctct tccttcccat gagatataaa
     8461 aaatatcatc atagtggcta acaaaagttt cgtctgcatc acagtagcgg gggctgtaaa
     8521 ggaatttaac ctttttccct attaatcttg cttaaagaac ctataatatt atatatttaa
     8581 tttttaaatt cttcttaaat tattttctat ataaatcatt gtataccttt tctgtgaaaa
     8641 tttctacatt ttttataaat tttattcatt tttatatttt tatgtatata aattcttttt
     8701 tgtaagttta ttaatttcta attatcttct ttaaatacat tgaaactaca tcagaaaatc
     8761 tagttatatc tcttgaatat ataaaatcat ttccatatat taatctttca gcttcaagtt
     8821 ctgattcttt tcctgtaaat actcctaata ctaatatatt ttgctttcta gcttttctca
     8881 cttcattggc tgtatctctc aaaccaacta tacccctata agccttttct cctcttaatg
     8941 ttctctcact actttttcct atctttacat catttggtct tccatcactg agaactatca
     9001 ggattttatt ttcttcatct ctatttatta gaccactaca tatagatttt attgccaaac
     9061 catctctatt attaccagca caaaaatatt caaatatatt ttcactattt tttatactat
     9121 catcataatc tttaaatctt tttaatattg tatagtctaa aaaactagaa aatcccatca
     9181 ctctatttgg tatgccaact tctgttagag catttgcaat tatgtaagct tgaattgcca
     9241 catttccctg atttctactt tgagagccac ttgcatccaa taatatatca ataacgtatt
     9301 tccctttttc attttctata tctttataaa atattttatt attattactt ctaccaactc
     9361 tccaagctct attggctaat atagtaccac aatcagaata tactctactt ttagcatttt
     9421 cttctattaa aattcttgat agactttctt ttaatctctt tatttgctgt ctatacattc
     9481 tagcatgttc tctaaatttt cctaaattat tttctttttg tcttgttaca tattttagtt
     9541 gaaatacatt attacactca cttctaagaa ctccatctgt aaagtgtatt ctacaacctt
     9601 catgaacatt tctacaattt tgtgtctcaa tttttttaat ttcaccttta ctcaaataag
     9661 tttttccata ataatgttct atttttgaat atatcttatt tgcagtgtct tcatcaacat
     9721 atataactcg gtctgctgaa ttgctacatt tagaatcatc aaaatcccct acaccttcta
     9781 caagcatgga tgaagatatt gaatctatat cactttcaat aatattttct tcttcatcac
     9841 tataaagttc ttcatacatg aaatcagcaa atgtatcaaa atttacttct acactttcta
     9901 cattattttc atcaataaga ctattttctt ctccatttaa tatgtattca aaataagtta
     9961 aatatataac atctaatgct tttaaaatct ccataatatc ttgattggta tctatatttc
    10021 ttatatcatt aactattctt ctagtcatac tatctaatgc tgggtgcttg tccatactat
    10081 aaagtacaaa tgtgtattta attttatcca taatattatc attgtgtatt ttggtaaaac
    10141 gtgaaacaat atctttataa gcatttcttc ttatgtcttc tatccctggc ctatctttaa
    10201 tgaccttttc ttcaactatt gtatttaata taacttgaat tagacccagt ataatatctt
    10261 tgttgtatcc ttttcttatt ctatttgtaa gatatttttt aactatatcc caatctacat
    10321 actttcttct agcacctgca attattgcaa aatatagacc tatttctttt gaagagtaat
    10381 ctttttctga tatatctata ctttcattgt aatcaccagc tattgtccat gataagttat
    10441 tagctctatt ttcaaattca taatcatcat atatccattt cataatctca cctatattaa
    10501 atatgactta ttggaaacac atctatactc tcccatttat taggtattct agttttaatt
    10561 acatctccaa ccatttcttt ctcatataca tcaaaagtct ttcctgtaag tcccatatta
    10621 attgcaagag ttggttttaa tcctcttctt atagtcttaa gagatgccat aagaccacgt
    10681 aaatcaatag ctttactaga tatctctcca ttttgagact tcaattgtaa atctaaaaat
    10741 attcctgcaa agtgtattag tttttcttca tcagcatctg aaaattcatt ttttaaaatc
    10801 atcattaact tatcttcttc tataggagga atatctatta ccataaatct agataccagt
    10861 gcttcattaa gttcttttgt tcctgcatat tcataattca tagtcccaat aaatcttgtt
    10921 gctggatgta gattgactct ctcataccca ggtacatcaa ttattcttct atagtctaaa
    10981 gctgaatgta ccacaactat agcatcattt tttgccatat taatttcatc aaacacccca
    11041 aaacctccat taatagcaca ctcataaact gagcctcttc taagtttaac ttcattgtct
    11101 ataaatgtat ctgtacctat aagtgttgaa ctgtctgtat ttatatgaaa tgatgtattc
    11161 cactgaggtc tattaaatat ttcccctaga ttatcagcaa gtaagttttt tcccgttgcc
    11221 tttggtcccg ataataatat attttcttct tctaaaatag ctgctataca catagacaag
    11281 atatctttac cataaaaata agttttagac tttgttactc tgtattctaa atctttttct
    11341 aatccataat aatttctaaa atacagtaca tcttcaataa gtttttcatc taccccttgc
    11401 acccttagat tatctattat atccatattt ttaccccttt tatataaata gtatttgttt
    11461 catttcttat caccatttta gcataaaagg atataagcta aaattgattt tttaatctcc
    11521 cccattttaa gtaaaaccat gcaccatttt atcactacaa aattaagagt actacttact
    11581 gatatttctt gattttattc gtctatacgt atataatata tactgataaa ttatgaggaa
    11641 aggatgattg aaatatggaa tatatgtctt gcccagaagt agcaaaaaaa tggggtattt
    11701 ctgaaagaag agtacaaaaa ctatgtgaag aaagtcgcat accaggagtt tcaaaactcg
    11761 ggtatatgtg gctgatacca aagaacgcag aaaagcctgt tgatggtaga acaaaaagaa
    11821 gaaaggaagt acaatatgaa tagcgttttg attatagatg atgacaaaga actttgtgct
    11881 cttatgaaaa aatgtgttga gcaagaaaat ttatctgcta ttactgcaca tggtggtgca
    11941 gaaggtctac atttagtcga taaaaataga cacacactct ctcttgtaat tttggacata
    12001 atgatgccag atatagacgg ttttcaagtt ctgaaaaaaa ttagagaaac aagtaatatt
    12061 ccagtaatta tgcttactgc taaaaatgac gaggatgata aagtttccgg actacgttta
    12121 ggtgctgacg attacctaac aaaaccgttc agcataaacg aacttatggc tcgtgtcaat
    12181 tctcttattc gtcggtatac tatgctaaac cctgctttta taacagacac agatttcata
    12241 ataataaatg gcatgattat tgacaagaca aaccgaattg tttctgtcaa taatattcct
    12301 gttcaactta caagcaaaga atttgattta cttgcttttc tggcttctaa taagggacgg
    12361 gtgtttacca aaaaacagat ttatacacaa gtatgggaag aagaatatgc ttttgacgat
    12421 agtaacatca tgtctttcat cagtaaattg agaaaaaaga ttgaaccaga ccccaaccat
    12481 ccattttata ttttgacagt tcgtggtgtc ggttatcgtt ttaataagga ggcttaacat
    12541 gaatacaagt gtctatctgc ttttgatatt ggctcttagc ctgattatta tagcgtacct
    12601 tgtttctgtc ctgctacgtg tccgaataca acttacactt ataaaagatg ctttagagga
    12661 tataaaaaat ggaaacctta atcgacgtat tttaacagat gaaaacgaca ttacaaaaca
    12721 aatttgctat gatattaacg aaatagcaat caatagccaa tttcaactta ttcagcaaaa
    12781 acaatcagaa caagcctaca aacagctaat gacaagtctc tcccatgatg taaaaactcc
    12841 acttgcttct ttggtcggtt atttggaagc agtagaaagt aaaattgttg taggagagga
    12901 aaaagacgag tatatccatg ttgcgtctaa taaggctcat tacttaaaga attttgtaga
    12961 aaatctattt gaatgggtaa aattggattc taaggaacaa gtttttcatt ttgatatttt
    13021 tgacttgaat gaattatccc gtaatattat atctgattgg atacctgttt tagaaagcag
    13081 tcattttgaa tatgaatttg atataccaga aatagagtac ttcttacgta tagacgcaaa
    13141 tgcatatacc cgtatcatta ataacctatt acaaaatatt attacccata gtagtggaaa
    13201 caaaatgaca ttgagaattt ttgaaaacaa agagcaagct caaattataa taacagataa
    13261 tgggaaaggt atatcttcag acaatctccc acatattttt gaaaggttgt accaatgcga
    13321 ccattcacga gcttcaaagg gaaatggttt aggcttggcg attgcaaagg aacttattaa
    13381 cgctcataag ggaaatatta ccgccaacag cactcccggt atgggaacag aatttacaat
    13441 attgcttcct aaagccctgt aaaagtacga ggctttctta ctctaaaaca agataaaagc
    13501 aagattatgg caaggttttg gcaaggttca tgttttataa ttctaattgt agttgatttt
    13561 gacgttgtat caactatctt ttgtagaaac aaatttatta aaagtgagga aattatatat
    13621 gaatgatttt gtgattgaaa caaagcaact tacaaaaatt tatgggaatc aaacagtagt
    13681 tgacaaagtc aatctccatg taaaaaaagg ccgaatatat ggtctgttag gacgcaacgg
    13741 agctgggaaa accacaatta tgaaaatgat tttaggattg acttcaatca cgtatggcga
    13801 ggtagatgta tttggagaga atattaaggg acgtgaaaaa caagtatatc cccgtatcgg
    13861 tgcaattatc gaaacgccag gattttatcc taatctgaca ggaacggaga acttggagat
    13921 ttttgcaaaa ctgcgtggta cagccgcccc taattctgta aaaagagcat tggaaattgt
    13981 aggcttacct tataaaaata aaaagctgtt tagtaaatat tcacttggca tgaaacagcg
    14041 acttggtatt gccaacgcta tcctgcatga cccagaactg ttagttttag atgagccaac
    14101 caatggtctt gaccctattg gtattgcgga gatgagaaag tttattaggg acttgagcgt
    14161 tgagcatgga aagacaattc ttatttccag tcatattctt tcagaaatct cattgttggc
    14221 tgatgatatt ggaattatcg accacggtgt tcttttggaa gaaagtagta tgagtgaact
    14281 agaaaagaaa aacagtaaat atatcctgct acaagtttca gatattccga agacatcact
    14341 tattttagag cgtcaattta acacgaagga ttattccgtt caagatgact acacgttaca
    14401 cctttataac actaatctgg atatgggtga aatcaataaa gcacttgtaa tgcagaatgt
    14461 aactgttatt agttctcaac tttgtaatga tactttagag gactacttta aaaaaatcac
    14521 aggaggagag ggcattgctt aaacttattc aaacagaatt tcttaaactg cgtcgtagga
    14581 aacttatttg gctgatgttg ttgtctgctc tcattatgcc gtttttcgca ctactatact
    14641 tcaattattt tggtaaaaca ggtgttgagc caataaagtt ttataaatgg tctgcatttg
    14701 gttatacact ttggattatt ttgcctgttg ttttgggtat attttgcacc atgcttatac
    14761 acgaagaaaa ccagtatgat atgctcaaac agctttggat tgtacctatt agtaaaatgg
    14821 gatacttttt tagtaaattt ttcgttgttt tgatttactc tatttgtttt atgctgatta
    14881 cagccgttgc ttctgtgtta tttagtgtac tttctggata tgtcgtattt agctgggcaa
    14941 gcattttata tttgttgaaa aaatgtttag aaattggtgt aatcactgct tttgtaatgt
    15001 tgccgatttt ggcaatcgct acatctcaaa aaggatacat tctcccaatt tgtatcacat
    15061 tggtatatgc cttttccggt tttgttataa tgacaataaa tatgtattta cacccattat
    15121 ccagtatggg agttattatc atgagaaata aagacattcc aggtcttata ttttcacagg
    15181 aaattaatgt cccattagca tttctttgta tttgtatttg gagtattgta tcagtattgt
    15241 ttgcaaatat tgcactagga agaagaaagt gaggtgtaga taatgtggaa attactttgg
    15301 gctgaatgtc aaaaaattcg tcgttcaaaa attgtttgga ttacagtttt tgcatccatt
    15361 atgatagcag tcatagtttt tgcagggggg caggatgtat ataatgaccc agatttacat
    15421 tatggcttaa agagcgttta tgacggttca cggtatatag acaatgcagg ttggtatatg
    15481 gacgcagtac aaccttggtc aacttttttt gttcttcctg ctgtcattgc cctattagga
    15541 agctatatta tttgtcgtga agaagaggag gacactatta aatccctgcg tcttattccc
    15601 ataaatgaaa caaatttaac catagcaaaa atgattatta cttttatatt cagtatactt
    15661 ctttatttgt tactctttac tataacattt ttgactgaat ccgttttaca tttttccgat
    15721 ttatcgacaa aattggtttt aagttgcatg aaagagtatt ttcttgatgg cataggtgta
    15781 ttctttgcaa tttctcccat tattgccttg gtatcgcgca tgaaaaaagg atattggctt
    15841 gcattagtat tcacagaagt ttattctatt gctggactat ttgcgggtat gtcaaatgtc
    15901 ttacaaacct tttttcctat tgcggcaata tttaatattt ctggatacta tataactact
    15961 ggagaaaaaa ttatggggag tatcatgagt ttattacttt gtgcctgcct ttctgcattt
    16021 atacttaaag ggctaaaaca caatgaaaaa aattgaaata ggtatatcaa aatgaaaaag
    16081 ataaaaaaac tgattattct aattgtattc ttgtttcttt ttggcatgtt acactgttat
    16141 actgaatgga aattcaacaa taacccacct aaaggggtaa tagaaagaat aaatgagtgg
    16201 actgataaga ttggactgga ttagtaactt atgttaatta tagtgaatgt aatattagca
    16261 agttattgtt tcgtatttta atactataac tttaaatatt tggttttaat cttccaaacg
    16321 aatataaaaa aactgtcaca gaggcaacat atttttgaat atttataaag tggtagtttt
    16381 gattttcaaa gctaccgcct tttcttctat ataagcaaac ttatcctcaa caaagtgtaa
    16441 aacatggtgc attttaagaa aaaagtacca cagacacaag caataaaaga aacgccgaga
    16501 acctacaaaa acgtagtgct tatgcagatt tacgacgcct tctattttct caaccgtctt
    16561 aatgaccttg tacaaaagaa atttttctaa tattttttat aatcttatct tgtgatgttt
    16621 tttatgtata aatgacttaa taacaaatcc aataaaaatt atggatattg gtataattag
    16681 aacgaggaat ttataatcat tataatgtga cattattctt acccaactct cagaaaaaat
    16741 atatcctata ctgattaatg aagtattcca tatggttatt cccacgatag atgatattac
    16801 aaaagttata atattttgac ctgctatacc tgctataaaa gatatgtatg ttctacataa
    16861 agggattaat ctacatacac aaacagaaat agaagagtat ttattaaaat aatcttgaga
    16921 tgcaaatatt cctttctttg cctttggaca tatctctatt attttattta tgatagattt
    16981 acctccccaa tttcccactg tataacaaaa tatcgaacca agtatacctg caattatact
    17041 taaaattaaa attgtcagaa atccaaaatg atttcttgca gcaattgctc cacataaagg
    17101 taaaacaact tcgctaggta atggaaaaca agcatactca atcataatta atacaaatac
    17161 agagattaat ccatattgta aaataaaact attgattaca gacacttact tatctatctc
    17221 ctttcttatt taaaggtttt aagggtacat gttctaagga ttctcaccct atatttaaag
    17281 aatcaatctc tttaaactat tatatgtatt tacacaaagc atttataaca tactttaaaa
    17341 atagtacctt aaaataagaa acttaataaa taaaaaaaga ttacgtggct acgtcctact
    17401 ctcccaggca gtttcccacc aagtaccatc agcgctagag agcttaactt ctgtgttcgg
    17461 aatgggaaca ggtgtatcct ctctgctatt gtaaccacat aatctttatg cttaatattt
    17521 ccattaagtt tttaataagt ttatagaacc tagtaatact agtttcttta gagttagcac
    17581 tctaaaaact acacatatat cttaatgaat gaacatcaaa t
//
LOCUS       DAEPKC010000083        17405 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.083, whole genome shotgun sequence.
ACCESSION   DAEPKC010000083 DAEPKC010000000
VERSION     DAEPKC010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17405)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17405)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17405
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.083"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(34..654)
                     /locus_tag="KR294_002802"
     CDS             complement(34..654)
                     /locus_tag="KR294_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBH0240865.1"
                     /translation="MQYIQELLDLTQNYWVLATIIGLLSAFIESFIPALPLVAIVTAN
                     AAIQGLFIGCLLSWIGSGLGTTSLFLLISRFNDSKLFNKLRNSKTEKAISWMDKQGFK
                     LLFIAYACPFMPGCLVTIASAFGKKDLKDFVPAMLAGKFVMFIVISYVASDIEGFITS
                     PLKIASFILLVFLSWKIGNRVNKNLENHNYDFHHKKHHNDKDDKMI"
     gene            complement(968..3106)
                     /gene="vanT"
                     /locus_tag="KR294_002803"
     CDS             complement(968..3106)
                     /gene="vanT"
                     /locus_tag="KR294_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine racemase VanT catalytic subunit"
                     /protein_id="HBH0240866.1"
                     /translation="MIRNKSYAGLDYFRIIAALLIIAIHTSPLLSYSKMADFVLTSII
                     ARIAVPFFFMLSGFFLISTYNYNCNKLKSFLKNVLFIYGIAIVIYIPLNIYTGYFSMN
                     NLVPNIIKDIVFDGTLYHLWYLPASIIGASIAYFLVKKLGLKYSLVITIVIYVIGMFG
                     DSYYGFLEKIPLLKNLYGYIFEVSDYTRNGIFFAPVFFILGGIISNKSNYMSTKNSLI
                     GFLISFLLMLCEGMFLHKLGVQRHDSMYIMLLPCMYFLFTALTFLKGSRARLLRTSSL
                     IIYIIHPMMIVVIRMFSKIFGIQTVLVDNSLIHYIVVSIASFIASIIIILILKPLKKD
                     LKGEHKVNTNRAWIEIDLNNLEHNVKMIQKAMPEDCELMAVVKANAYGHSAFEVATCA
                     NQIGVKAFAVATIDEGIDLRRYGILGEILILGYTNPIRAKELHKYNLTQSVIDLNHAI
                     SLNKQKYNIKSHIKIDTGMHRLGFDVNDVRSILKAFKLKYLDICGIFTHLCVSDSLKD
                     EDVDFTNKQIECFYKLIDFLLKKGIKIPKVHIQSSYGFFNYPNLKCNYVRIGIALYGI
                     LSFPNDTTKLQLDLRPVLSLKSQVILIRKIQKDDSFGYGRVFIASRDSVIAILSIGYA
                     DGIPRNLSCGKSYVIINGCRAAIVGRICMDQLAVDITDIPNVEVGNTAIIIGRDNLSE
                     LSVSEVANNSCSISNELLSRVGRRLNVIKK"
     gene            complement(3124..3930)
                     /locus_tag="KR294_002804"
     CDS             complement(3124..3930)
                     /locus_tag="KR294_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HBH0240867.1"
                     /translation="MMNNILLDKNKEDKMTNTILLTKDKVYDGNLILVNAFLPVKTSE
                     DIDLIPVDTRFPSILMKREATNILQNILKSICGINEIVPVSGYRTAEEQQDIYSSSLR
                     DNGKDFTKKFVALPNHSEHQTGLAIDLGLKKEVIDFICPEFPYNGICNEFRKAALHYG
                     FIERYQCKKEEITGISQEPWHFRYVGYPHSEIINKMNLALEEYIEYIKRFSYTNCLKI
                     EDKEKIIEIFYVPIHTKEEVRISIPEQCVYQISGNNKDGFIVTFWRNRKD"
     gene            complement(3927..5027)
                     /gene="vanG"
                     /locus_tag="KR294_002805"
     CDS             complement(3927..5027)
                     /gene="vanG"
                     /locus_tag="KR294_002805"
                     /EC_number="6.3.2.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-serine ligase VanG"
                     /protein_id="HBH0240868.1"
                     /translation="MNNKKIAVIFGGNSTEYDVSLQSAFAVLENLNTEKYDIIPIGIT
                     REGNWYHYIGDYNNIQNNTWFERDTDIIPVIVSQNRVKNGIIEFLIPDAVSQNHIPNS
                     AIESCENDIKYTKLDFVFPVLHGKNGEDGTVQGLFELAGIQVIGCGTLSSALCMDKDK
                     SHKLVHSEGIKVPKSILLKYSDKFNVAELSKDLTYPLFIKPVRAGSSFGISKIYKKEE
                     LQVAVDLAFEHDNEVIIEENIDGFEVGCAVLGNNDLLVGRVDEIELSKGFFDYTEKYT
                     LKSSKIHMPARIDLDCEKRIQETAKIIYRTLGCSGFARVDMFLTPSGEIIFNEVNTIP
                     GFTSHSRYPNMMKGIGLSFEEILDKIIEVYIK"
     gene            complement(5288..6370)
                     /locus_tag="KR294_002806"
     CDS             complement(5288..6370)
                     /locus_tag="KR294_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBH0240869.1"
                     /translation="MRTALMAFIAIIFIWILYSFILYGKFSIWIVSFFENAFRMEYKA
                     ALNLYQQIFRNSMELFMILAMVIVFFIIFRVYLNWFTKYFSEINQGIDSLIKEDVGEV
                     ALSPELLAIEKKINSIKHILEQRKFETQMAEQRKNELIVYLAHDLKTPLTSVIGYLTL
                     LRDESQISEELRKKYLSISLDKAERLEDLINEFFEITRFNLSNISLEYSTVSLTRMLE
                     QLTYEFKPTLMSKNLKYTLNVTPNMMIRCDVNKMQRVFDNLLRNAVYYSFEDTTIEIT
                     AVQEDDYIKLKFINHSNTIPEEKLERIFEQFYRLDTSRNSNSGRAGLGLAIAKEIVEL
                     HNGTITAHSENNIITFKVIIPIVGNL"
     gene            complement(6420..7121)
                     /locus_tag="KR294_002807"
     CDS             complement(6420..7121)
                     /locus_tag="KR294_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanG-Cd-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HBH0240870.1"
                     /translation="MNENILIVDDEKEIADLIEVYLKNEGFTVYKFYTGKEALECIES
                     KNLDMAILDIMLPDIDGFHICQKIREKYYYPIIMLTAKIEDIDKIMGLTIGADDYITK
                     PFNPLEVVARVKTQLRRYMRYNNSYEQQSIIVNEYDIKGLIINKETHKCSLFGKEVAL
                     TPIEFSILWYLCEHQGKVVPSEELFEAVWGEKYLDNNNTVMAHIGRLREKIHEPSKNP
                     KFIKTVWGVGYTIEK"
     gene            complement(7555..10086)
                     /locus_tag="KR294_002808"
     CDS             complement(7555..10086)
                     /locus_tag="KR294_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBH0240871.1"
                     /translation="MSLKSLKIKENLYWVGSLDPDLRVFDIIMYTPYGTTYNSYVLKG
                     TEKTVLFETVKDKHFDNYIERLNDLNIDFEKIDYIVVSHTEPDHAGSVEKLLDLAKNA
                     KVVASETAIKYLKEIVNKDFEYVAVTDGDTLSIGDKTLEFFSVPMLHWPDTIYTYIKE
                     DKTLVTCDSFGSHYSNDKIVNTLDEDEEKDYLDALRYYYDCIMGPFKPSMVTAIEKIK
                     DLDIDTVCPGHGPVLTENPRKIIDLYYNWSVNEQIKLEKEVTICYVSAHGYTKIMAEA
                     IKAYIEKNSNYKVNLFDVIEHKQEDILAKIAVSQGVLFGTPTILGDALKPIWDILISL
                     NPVLHGGKVASVFGSYGWSGEGIENAMERISQLRMTAVKPFAVNFKPSNEEIDKLHSY
                     TGKFLDKLNSTFGSKKKTKKFKCVICNEVFEGDSAPSVCPVCGAKEDQFIEVEEDEVT
                     FRKDTDEYFVIVGNGAAGFYAADAIRKRNKTCKITMISNEDELTYYRPALSDGINEEL
                     GSDFYMEDKDWYDKNNIVVILGTNVDKLDEVNKTIIVNDGAIKFDKLVIATGSRNFIP
                     PIKGHDLENVFTLRNIKDLYSVKEALEKSKKVVVIGGGLLGLEAAWEFRLKGLEVVVV
                     EAMDSILSKQLDKEGSKILEQCVRDTGIDVRLGVAVDGIEGDGKAQKVVFKDGDSVDC
                     DMVVFSIGVRANTQMVQDTSVKIDRGIVVDKTLQTNVKDIYACGDVAQVGNISLAIWP
                     SSVEMGKIAGANASGDNLTFESEVYPVSLDAMNVKVFSIGNIQNFDKEISSKDEGQRI
                     YKKLFMKDGSLVGAILINDLSCTVKLIRLISEKGDFEDIMKADIL"
     gene            complement(10194..10811)
                     /locus_tag="KR294_002809"
     CDS             complement(10194..10811)
                     /locus_tag="KR294_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HBH0240872.1"
                     /translation="MCKKMYLLVVGILIAGLLTACNGSPTKDSEQAQDNTKKEANVSN
                     NALKDEKNNENLMEQDFKVPYTDAINIFKDKYKDADIVDLSLERDLNKFVYTVEGVDD
                     NNEYKMKIDANTKDVLEDKTEKLDSEDLNGVARKEKLDFNDIMTPQQAMEIALKEQNG
                     MVKEWSLDKDLDVTFYKIRIDKDKNEYDIKVDSKKGTVLKVEKED"
     gene            complement(11170..12054)
                     /locus_tag="KR294_002810"
     CDS             complement(11170..12054)
                     /locus_tag="KR294_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HBH0240873.1"
                     /translation="MDTTKIDDISKLDLNNLDINKMDMGGIMESLLEWATTSGVKLII
                     GILILSIGFKIIKKFVNHVMLLLSKRDIDLTLRRFLKSLLLSVLKVAVIIIVLEYWGM
                     SLSSFAAVIASAGVAIGLALQGSLSNFAGGFIILLIRPFKVGDYVEAAGHGGTVEQIG
                     LFYTQLVTPDNKQILIPNGSVSNDSLINYSAKNTRRVDLTFSVGYEDDILHVRRVLKD
                     IVNNHKLIINEPEPFIGVVEHGDNAIKFATRVWCKTEDYWTIYLDLLEEVKVRFDEEG
                     ITIPYPKMDLTVKELNKI"
     gene            complement(12247..13497)
                     /locus_tag="KR294_002811"
     CDS             complement(12247..13497)
                     /locus_tag="KR294_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH0240874.1"
                     /translation="MKSYTKAKWSVWGIITFSFVLVLFLRMSTAVVSDNLANELGFNS
                     IQISNIASFCLYAYAFMQIPAGILIDKYGARKISSLGIIMASLGSILFGLIQSIELAY
                     ISRVIVGAGTSVILLCILKIQGRWFNKSEFASATAKFSFVGNLGGVLATFPLVFLSEL
                     VGWRNSFLLIGIIGVVIGCFMYIIVRDTPKEYGFNIDTEPYEKSEKVNIVDGIKSVIK
                     NKSTWYNSMIMFSFVGLTSAFISLWGVRYIMDVYGVSKSFSAFIVSFFTYGFIFGSII
                     MDFVFAKIRSSKFNIIKFGAMIDLFIWIVIVVVYQVKPPIIVLPISFFIMGCIVMSHL
                     QVFNDAKYKNKEIYSGLATSVINTFEFIGSGIINLIIAISLQVNSYNIVDGYKKGFVV
                     FIVLSIITIVSSHIGVKNDDFKAI"
     gene            complement(13719..14483)
                     /locus_tag="KR294_002812"
     CDS             complement(13719..14483)
                     /locus_tag="KR294_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0240875.1"
                     /translation="MLGKLLKYELKASGRIFIPLYIAILIVAVFNGIFMNTNILQVQG
                     IGILVLTSLFMALGVLTIVVTIQRFRKNLLGDEGYLMFTLPVSTSSLILSKCITALIY
                     AVLSFIVAVFTFGVLMLFGTSGILLPEILDLFNTSFKWISENFLDILLLVVVMFISYS
                     SFILLLYTSISMGQLPKFNKHRNIVAFASFIAINIVISIVGDAVGSILPNEDTNMVYH
                     LYQSPSFMLAILGSLVVAIALFFATKFILDKKLNLE"
     gene            complement(14477..15202)
                     /locus_tag="KR294_002813"
     CDS             complement(14477..15202)
                     /locus_tag="KR294_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0240876.1"
                     /translation="MDKNISNVSQDGIVEFKGVNKSYGTKNVLKNIDLNIPKGKIVGL
                     LGPNGSGKSTMIKLMNGLLQPDNGEIMINGMKPSIDTKKIVSYLPERTYLNDWMKVSD
                     LLKFFYDFYSDFDVRRANEMIKSLDIDVNEKLKTMSKGTKEKVQLILVMSRNASIYIL
                     DEPIGGVDPAARSYILKTILKNYSEDSTLLIATHLISEIENICDEIIFISKGEIVLQG
                     DVEAIREEKGKSIDALFREEFKC"
     gene            complement(15204..15572)
                     /locus_tag="KR294_002814"
     CDS             complement(15204..15572)
                     /locus_tag="KR294_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH0240877.1"
                     /translation="MEWELDNNKPIYIQLVEHLKLKIISGEIKIGSKLETVRALAEDA
                     EVNPNTMQKALTELERQGLVYSQRTKGRFVTDDKEKIKAMKEEIANVEINTLKVTLEK
                     LGYDRDEMLKLITENLKGEL"
     gene            complement(15748..17292)
                     /locus_tag="KR294_002815"
     CDS             complement(15748..17292)
                     /locus_tag="KR294_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HBH0240878.1"
                     /translation="MRNLQKKLMFFLFICIILQITYTTPVYSLCKLYKNNSINNFESI
                     VSNNQLISKHAIQIILIMAIICVILIFYIIYDKLNFKIKLQRIAYTDNLTGANTIDKF
                     VIDANKILCKNTQVKYALLYIDIDKFKYINDLFGYEVGNEILRNLTKIIKRNIFEEEM
                     FARISADNFIIIMKYIEEEDITKRLKTIFEELDLFNNNQEEKYKLVLSCGIYFILPED
                     RDINSIIDRANIPHKMAKGGHKSSYAFYDNKIHDQEIKEKEMENTMFSSLENKEFIIY
                     LQPKIELNTGEIQGSEALVRWKRPDKGLIPPNEFIPFFERNGFVINLDLYVLEEVCIY
                     LRKWIDAGINPVTVSVNVSRIHLYCNNFIETYKNIIDKYNIPAKYIELELTESIIFDN
                     FDILIDIMNNLKKIGFLISMDDFGSGYSSLNMLKEIPMDILKLDQKFIMETYNSKRSK
                     IIVTKVIEMAKELGMKVISEGVETEEQFKLLKEVKCDMAQGYLFGKPMPIEEFEHLIV
                     SNLVRG"
BASE COUNT         5959 a         3077 c         1747 g         6622 t
ORIGIN      
        1 aatcatttta agatacgttt tatttcgtac aagctaaatc attttatcat ctttatcatt
       61 gtgatgtttt ttatgatgga aatcataatt atgattttca agatttttat ttactctatt
      121 tccaatcttc catgacaaaa acaccaataa tataaatgat gctatcttta aaggacttgt
      181 tataaaacct tctatatcac ttgccacgta acttataact ataaacatta caaattttcc
      241 tgccaacatt gctggcacaa aatcttttaa atctttttta ccaaaagctg atgcgatagt
      301 aactaaacaa ccgggcataa atggacaggc atacgctata aataataact taaatccctg
      361 tttatccatc caacttattg ctttttcagt tttactattt ctcaacttat taaaaagctt
      421 actatcatta aatctgctta ttaataagaa taatgaagtt gtcccaagtc ctgagccaat
      481 ccatgataac aaacatccaa taaataatcc ttgtattgca gcatttgctg taactatagc
      541 aacaagtggt aaggctggta taaagctttc tataaatgca cttaataagc cgattattgt
      601 ggctaacacc caataatttt gagtcaaatc aagtagttct tgtatatact gcatattgct
      661 tttccccttt tttaacttta actattatta tatactctat atgtttatta tataccaatc
      721 tcaaaaaatg aatctaatat taaaaagtaa ataatctata taagtttaca gttaaggtat
      781 aattatttta ttatatatta taacaaaaaa ggtgatgttt caaaataaaa atctgaaaca
      841 tcaccttttt ataacttaaa ttgtcatgta agttataaaa aatatatatt agacataata
      901 ttactaaaaa tgtctagtca gagtaaaata aattacacag tacaacaaat attactattt
      961 aattgagtta cttctttata acatttaacc ttcttcctac tctgctcaat aattcattcg
     1021 atatactaca tgagttattt gcaacttcag aaacagataa ttcagataaa ttatctcttc
     1081 ctattattat tgccgtatta ccaacttcta cattaggtat atctgtaata tcaacagcaa
     1141 gttggtccat gcaaattcga cccactattg ctgctctaca accatttatt attacgtaac
     1201 tttttccaca ggataaattt ctaggtatac catcggcata gccaatagat aatatagcaa
     1261 ttacgctatc tctgcttgca ataaagactc ttccatatcc aaaactatca tctttttgta
     1321 tttttctaat aagaattact tgtgatttta aggataaaac aggtcgtaaa tcaagttgca
     1381 atttagtcgt atcatttgga aaacttaata tcccgtataa tgcaattcca attcttacat
     1441 aattacactt aagattggga taattaaaaa aaccataact actttgaata tgtactttag
     1501 gaatttttat accttttttt aacagaaaat caattaactt ataaaaacat tcaatttgtt
     1561 tatttgtaaa gtctacatct tcatctttca gactatctga aacacacaag tgtgtaaata
     1621 tgccacatat atctaagtat tttaatttaa atgcctttaa aattgacctc acatcattaa
     1681 catcaaaacc cagtctgtgc atacctgtat caattttaat gtgtgatttt atgttgtatt
     1741 tctgtttgtt taaagagata gcatgattaa ggtcaataac actctgtgta agattgtatt
     1801 tatgaagttc ctttgccctt attgggttag tatatccaag aatcaatatt tctcctagta
     1861 ttccatatcg acgtaaatca atcccctcat ctattgttgc tactgcaaat gcttttacac
     1921 ctatttggtt tgcacaagtc gctacttcaa aagcactatg accataggca ttagctttta
     1981 caactgccat caattcacaa tcttctggca tagctttttg tatcatcttt acattatgtt
     2041 ccaaattatt taaatcaatt tcaatccaag ctctattggt atttacctta tgttctcctt
     2101 tcaagtcttt ttttagaggt ttaagaatca atataataat tatagaagct ataaaagatg
     2161 ctatacttac cactatataa tgaataaggc tattgtcaac caagacagtt tgtattccga
     2221 atattttaga aaacatacga ataacaacaa tcatcatagg atgtataata taaataatta
     2281 atgatgatgt tcgcaataac ctagctcgag aacctttcaa aaatgttaag gctgtaaata
     2341 agaaatacat acatggcaat aacataatat acatgctatc atgacgctgt acccctagtt
     2401 tatgtaaaaa cattccctca cataacataa gtaagaatga tataagaaat ccaatcaagc
     2461 tatttttagt tgacatataa ttagatttat tagatattat tccaccaagt atgaaaaata
     2521 caggtgcaaa aaatatacca tttcgtgtat aatctgatac ttcaaaaata tacccatata
     2581 aattctttaa tagtggtatt ttttctaaaa aaccataata actatcacca aacataccaa
     2641 ttacataaat aacaatagtg attactagtg agtactttaa acctagtttt tttacaagaa
     2701 agtatgcaat acttgcacca ataattgatg caggaagata ccataaatga tataaagtcc
     2761 catcaaatac aatgtcctta ataatattgg gcactaaatt attcatggaa aaatatccag
     2821 tgtaaatatt taagggaata taaattacaa tagctatccc gtaaataaat aatacatttt
     2881 ttagaaaaga tttcagttta ttacaattat aattatatgt tgaaattaga aaaaagcctg
     2941 atagcataaa aaagaatggc acagcaatac gagcaattat actagttaac acaaagtcag
     3001 ccattttact atatgataat aatggagatg tatgaattgc aattataagt aatgcagcta
     3061 taatcctaaa ataatcaagc cctgcataag atttattcct aatcattctt gttcctccat
     3121 ttcttagtcc tttctatttc tccaaaatgt cacaataaaa ccatccttat tgttacccga
     3181 tatttgatat acacattgtt caggtataga gattctcact tcttctttag tatgaatagg
     3241 cacataaaag atttctataa ttttttcttt atcttctatt tttaaacaat ttgtatacga
     3301 aaatctctta atatattcta tatattcttc aagagcgaga ttcattttat tgataatctc
     3361 agaatgcgga tatcccacat aacgaaaatg ccatggttct tgagatattc ctgttatttc
     3421 ttctttttta cactgataac gctctataaa accataatgt agtgctgcct tacgaaactc
     3481 attacaaata ccattataag gaaattcagg gcagataaaa tctataactt ctttctttaa
     3541 ccctaaatca atagcaagcc ctgtctgatg ttcactgtga tttggaagtg ctacaaactt
     3601 tttagtaaag tcttttccat tgtcacgcag agaacttgaa tatatatctt gttgttcctc
     3661 tgcagtacga tatccactta caggtactat ttcatttatt ccacatatac tttttaaaat
     3721 attttgtaaa atgtttgtag cttcacgttt cataagaata cttggaaacc ttgtatctac
     3781 aggaattaaa tctatatctt cagatgtttt aactggtaaa aaagcattta ctagaattag
     3841 attcccatca taaactttat ctttagtcaa taagatagta tttgtcattt tatcttcttt
     3901 atttttatct aataaaatat tattcatcat tttatgtaca cctcaattat cttgtccaat
     3961 atttcttcaa aagacagtcc aatacctttc atcatatttg gataacgact atgagaagta
     4021 aagccaggaa ttgtattgac ttcattaaaa ataatttcac cagatggagt taaaaacata
     4081 tctactctag caaatccaga acatccaaga gttctataaa taatttttgc tgtctcttgt
     4141 attcttttct cacaatccaa atcaattcta gctggcatat gaatttttga acttttcaat
     4201 gtatattttt ctgtataatc aaaaaatcct tttgacaatt ctatttcatc tactcttcca
     4261 acaagtaagt cattgtttcc taaaactgca caccctacct caaaaccatc aatattttcc
     4321 tcaattatta cttcattatc atgttcaaaa gccaagtcta ctgctacttg taactcttct
     4381 tttttataaa ttttactaat accaaatgat gaacctgcac gcacaggttt tataaataat
     4441 ggataagtta agtcttttga cagttcagcc acattaaatt tatctgagta ttttagtaat
     4501 attgattttg gtactttaat accttctgaa tgaacaagtt tatgtgattt gtctttgtcc
     4561 atacataatg ctgaagaaag agtaccacat ccaataacct gtatacctgc caattcaaat
     4621 aacccctgca ctgttccatc ttctccattt tttccatgca gtacaggaaa cacaaaatca
     4681 agtttagtgt atttaatatc attttcacat gattcaatag cactatttgg aatatgattc
     4741 tgagaaacag catcaggaat taaaaattca ataataccat ttttgacacg gttctgcgaa
     4801 acaataactg gaattatatc agtatccctt tcaaaccaag tgttattctg gatattatta
     4861 taatctccaa tataatgata ccaattaccc tcccttgtaa ttccaattgg tataatatca
     4921 tatttttccg tattcaaatt ctcaagtact gcaaaagctg attgtaatga tacatcatat
     4981 tctgttgagt ttccaccaaa tataactgca atttttttat tattcatctt tgattctcct
     5041 ttgttgattt atttattttt atacaatcta cagaaacatg ttaaaatact ttttctattt
     5101 caaatccaat caaccttcac ttacaattgc atctgttcca cataatatat tttcacattt
     5161 ttctattgat ataattactg tatcaaaata aaagcactct tgttttgata cagtaattat
     5221 atcaataaca agagtgctct ttatttattt atcctaaaga atttcctatt tttttatact
     5281 taaattctta caaatttcct acaatcggaa taataacctt aaaggtaatt atattgttct
     5341 cgctatgagc tgttattgtc ccgttatgaa gctccactat ttctttagct atagcaagtc
     5401 ccaacccagc tctaccactg tttgaattac gagatgtatc caacctgtaa aattgttcaa
     5461 aaatacgctc aagtttttcc tctggaatcg tattgctatg atttataaat ttaagcttta
     5521 tataatcatc ctcctgtaca gctgttattt caatagtagt atcttcaaaa ctataataaa
     5581 cagcatttcg taataagtta tcaaatacac gttgcatttt attaacatca caccttatca
     5641 tcatatttgg tgtaacattc agtgtatatt ttaaattctt actcatcaaa gtaggtttaa
     5701 actcatatgt tagttgttca agcatacgag ttaagcttac tgtactgtat tcaagtgata
     5761 tatttgataa attaaacctt gtaatttcaa agaattcatt aattaaatct tcaagacgct
     5821 ctgccttatc caacgaaata gataaatatt tttttcgcag ttcttcagaa atctgacttt
     5881 catctcgaag tagtgtcaga taccctataa ctgatgtaag tggtgttttt aaatcatgtg
     5941 caagataaac aataagttca ttcttacgtt gttctgccat ttgtgtctca aatttacgtt
     6001 gttcaagtat atgtttaatt gagtttattt tcttttctat tgccaataac tctggagata
     6061 aagccacttc tccaacatct tctttgataa gagagtcaat accttgattt atttcactaa
     6121 aatattttgt aaaccaattt aaataaacac ggaatattat aaaaaacaca atcaccatag
     6181 ctagtatcat gaagagctcc atactattac ggaaaatctg ctgatataaa ttcaatgcag
     6241 ctttatattc catacgaaaa gcattttcaa agaatgatac tatccagata gaaaacttac
     6301 catacaatat aaaagaatat aaaatccata tgaaaataat ggctataaat gccattaaag
     6361 ctgttctcat aaaaatttta tttctcactt gagtaaagtc aggattgact ttaatatttt
     6421 tacttttcaa ttgtataacc tactccccat acagttttta taaatttcgg gtttttagaa
     6481 ggttcatgaa ttttttcacg taatcgccct atatgagcca taactgtgtt attattatca
     6541 agatattttt ctccccatac agcttcaaac aattcttcag aaggaaccac ttttccttga
     6601 tgttcacata aataccaaag aatagaaaat tcaatcggtg ttaatgctac ttctttccca
     6661 aataaactac atttatgtgt ttctttattg ataatcaatc ctttaatatc atactcatta
     6721 acaattatcg actgttgttc ataagaatta ttatatcgca tatatcttct taattgtgtc
     6781 tttactcttg caacaacttc caaagggtta aatggctttg ttatataatc atcagcacct
     6841 atggttaaac ccattatctt gtctatatct tcaattttag ctgttaacat aatgatagga
     6901 taatagtatt tttctcgaat tttctggcaa atatgaaatc catcaatatc aggaagcata
     6961 atatctaaaa tagccatatc caaattttta gattcaatac attctagagc ttccttacct
     7021 gtataaaact tgtatactgt aaaaccttca ttttttaaat atacttcaat taaatctgct
     7081 atttcttttt catcatccac aatcaaaata ttttcgttca tagattattt ttcactctcc
     7141 ttattatcga ggtcatcatt tataatattg gtaaatttac atatcaaata attacaagca
     7201 tatttgtaac taatttttat aagaaaagaa ctactacatc agaatgtgtt gatgctacta
     7261 ttggaacaca aaaactgaga ttaattgtta ttataaaaac tcccctaaca cgtccttatt
     7321 atcgcataac aggtattaac tttcaataaa aatatctatc agtcaaacac aattcaattt
     7381 attataccag agacaatcca tataaaaaac aattaaacct atgtatgtaa ccacagacat
     7441 tactaaaatt tccatgttat tttatataaa aattcaaaaa aggagttgaa tttaaaattt
     7501 gattagaaaa aaatcaattt taagacaact cctttttatt ttaatgtatt taaattatag
     7561 tatatcagcc ttcataatat cctcaaaatc acctttttca gatattaatc ttatcaattt
     7621 aacagtacag cttaaatcat ttataagtat agctccaact aatgaaccat ctttcataaa
     7681 taatttttta tatattcttt gaccttcatc ttttgatgaa atttctttat caaaattttg
     7741 tatattacca atactaaata cttttacatt cattgcatct aatgaaactg gatatacttc
     7801 actttcaaat gtcaaattat ctccacttgc atttgcccct gctatttttc ccatttctac
     7861 tgaagatggc catattgcta aactaatatt tcccacttgt gcaacatctc cacaagcata
     7921 tatatcttta acatttgtct gtaatgtctt atctacaaca atacctctgt caatttttac
     7981 agatgtatcc tgaaccattt gagtgtttgc tcttacacca attgaaaata ctaccatatc
     8041 acagtcaaca ctatctccat ctttaaatac aactttttga gcttttccat caccttcaat
     8101 accatcaact gctacaccca atcttacatc tattcctgta tctcttacac attgttctaa
     8161 tattttactg ccttctttat caagttgttt tgatagtatg ctatccatgg cttcaactac
     8221 tactacttct aatcctttta gtctaaattc ccatgcagct tcaagtccca ataaaccgcc
     8281 accaatcact acaactttct tagatttttc tagtgcttct tttacactat ataaatcttt
     8341 tatatttcta agagtaaaca cattttctaa atcatgaccc ttaattggtg gtataaagtt
     8401 tctacttcct gtagctatta caagcttatc aaatttaata gctccatcat tcactataat
     8461 agttttattc acttcatcta atttatctac attcgttcct aatattacta ctatattatt
     8521 tttatcatac caatctttat cttccatgta gaaatctgaa ccaagttctt catttatacc
     8581 atcagaaagt gcaggtctat agtaagtcaa ctcatcttca ttagaaatca tagttatctt
     8641 acaagtttta tttctttttc ttatagcatc tgctgcataa aaaccagctg ctccatttcc
     8701 tactattacg aaatattcat cagtatcttt tctaaaagta acttcatctt cttcaacttc
     8761 tataaattgg tcttccttag ctccacatac agggcataca ctaggagcac tatcaccttc
     8821 aaaaacttca ttacaaatta cacatttaaa tttcttagtt ttctttttac ttccaaaagt
     8881 agaatttaac ttatctagga atttacctgt ataagaatgt aatttatcaa tctcttcatt
     8941 tgatggttta aagttaacag caaaaggttt tactgctgtc attctaagct gacttattct
     9001 ctccatagca ttttctatac cttctccact ccatccatat gaaccaaata ctgaagcaac
     9061 ttttccacca tgaagaactg ggtttaacga tattaatata tcccatatag gctttaacgc
     9121 atctcctaat attgttggtg ttccaaataa tacaccttgt gatactgcta tttttgccaa
     9181 aatatcttct tgcttatgct ctattacatc aaataaattt actttatagt tgctattttt
     9241 ttcaatatat gcttttatag cttctgccat aatctttgta tatccatgtg cagaaacata
     9301 acaaattgta acttcttttt ctaactttat ttgttcattt acactccagt tgtaataaag
     9361 gtctataatt tttctaggat tttcagttaa tactggacca tgacctggac atacagtatc
     9421 tatatctaaa tcttttatct tttctatggc agttaccata gatggtttaa atggtcccat
     9481 tatacaatca taatagtatc tcaaagcatc caagtaatcc ttttcttcat cttcatcaag
     9541 tgtatttact atcttatcat tactatagtg actaccaaat gaatcacatg ttacaagagt
     9601 tttatcctct tttatatatg tgtatatggt atctggccaa tgaagcatag gtacagagaa
     9661 aaattctaaa gttttgtccc caattgataa tgtatctcca tctgtaactg caacatattc
     9721 aaagtctttg tttacgattt ccttaagata tttaattgct gtttctgaag ctactacttt
     9781 tgcattttta gctaaatcca aaagcttttc aacgcttcct gcatggtctg gttcagtatg
     9841 acttacaaca atatagtcta ttttttcaaa atctatattt aaatcattta atctttcaat
     9901 ataattgtca aaatgcttat ctttaactgt ctcaaataaa actgtttttt ctgttccttt
     9961 taatacatat gaattataag tagttccata aggtgtatac ataattatgt caaatactct
    10021 taaatcaggg tcaagcgaac ctacccaata taaattttct tttattttta gcgatttcaa
    10081 tgacataccg tactcctcct aaaatagtta tttagtctct ttatacccta cttgttatat
    10141 tttaaacaaa ttttattcaa aaaagaaatt attttaaaga tagtttaaat cttctaatct
    10201 tctttttcta ccttcaatac agttcccttt ttagaatcta cttttatgtc atattcattt
    10261 ttatctttat ctattcttat tttataaaaa gtaacatcta aatctttatc taaactccac
    10321 tctttaacca ttccattttg ttcttttaat gcaatttcca tagcttgttg aggtgtcatt
    10381 atgtcattaa aatctaattt ttcttttcta gcgactccat ttaaatcttc tgaatccaac
    10441 ttttctgttt tatcttctaa tacatctttt gtattagcat caattttcat cttatattca
    10501 ttattatcat ctacaccttc cacagtataa acaaatttat ttaaatctct ctcaagactt
    10561 aaatctacta tatcagcatc tttgtatttg tctttaaata tgtttattgc atctgtgtat
    10621 ggcactttaa aatcttgttc cattaaattt tcattatttt tttcatcttt taaagcgtta
    10681 tttgatacat ttgcctcctt ttttgtatta tcttgtgctt gttctgaatc cttagttgga
    10741 ctcccattac atgcagttaa taaacctgct ataagtatac ctaccactaa taaatacatt
    10801 tttttgcaca taaaaaccct ccttaaataa ttaatttatt ctatattatg ccctctaaac
    10861 cctttattta cccttttata ttaaaattcc tcctatttta gtagttttaa aactttatac
    10921 tcattaagat taaatctaca taaaaataat attgtctcaa aatagaaaca gacctctttt
    10981 ttattgttga aataataaaa atatatttga tttcatacaa aaagagtgcc tcatgaacta
    11041 aaaagttcat tttgagacac tcccattttt tatattttca cttacaaaat aacaggactt
    11101 attaattttt cacaaatctt ataaatatat ctatataata ttcttaaatt taaacactac
    11161 ataaaaaaat taaattttat ttaattcttt taccgttaaa tccattttag gatatggaat
    11221 cgtaattcct tcttcgtcaa acctaacttt aacctcttct agtaaatcaa gataaattgt
    11281 ccaataatct tctgtcttgc accaaactct agttgcaaat ttaatagcat tatctccatg
    11341 ttctactact cctataaatg gttctggttc atttattatt aatttatgat tattaacaat
    11401 atctttaagt actcttctaa catgtagtat atcatcttca taccctacac taaaagtcaa
    11461 atcaactcgt ctagtattct ttgctgaata gtttattaga ctatcatttg atacagaacc
    11521 attaggtata agtatctgtt tattatctgg agtaaccaat tgtgtataaa aaagtcctat
    11581 ttgttcaacc gttcctccat ggcctgctgc ttctacgtaa tctcctactt taaaaggtct
    11641 aatcaatagt ataataaatc ctccagcaaa atttgataga ctaccttgta aagccaaacc
    11701 tattgctacc cctgctgatg ctatcacagc agcaaaactg gacaaactca ttccccaata
    11761 ttccagaaca atgattataa cggcaacttt aagtacactc aaaagaagag acttcaaaaa
    11821 ccttcttaaa gttaaatcaa tatctctttt actaagtaat aacataacat ggtttacaaa
    11881 tttttttatt attttaaatc caatagaaag tataagtatg cctattataa gttttactcc
    11941 gcttgtagta gcccattcta atagactttc cattatacct cccatatcca tcttattaat
    12001 atctaaatta tttaaatcta acttgcttat atcatctatt ttcgtcgtat ccataaaaaa
    12061 ctccttacct tatattttag aaccaatatt atagtttaaa gttcttattt tctatttaat
    12121 ataatacaat accatttgta catagtaaac aagatttata ttccaattat acatcttagg
    12181 aaaatgcaaa ctatttgtta tatatatatg caaaatataa tactaaatta aactattaat
    12241 aaaacactat atagccttaa aatcatcatt ttttacccct atatgagatg atactatagt
    12301 tataatactt agtactataa atactacaaa acctttttta tatccatcaa ctatattata
    12361 tgaatttact tgtaaagaga tagctataat caaattaata attccacttc ctataaattc
    12421 aaaagtatta ataacactag ttgccagtcc agaataaatt tctttatttt tatacttggc
    12481 atcattaaaa acctgtagat gtgacataac tatacatccc ataataaaga atgatattgg
    12541 taaaactata attggtggtt ttacctggta tacaactaca attacaatcc atataaacaa
    12601 atctatcatt gccccaaatt ttattatatt aaatttgcta gaccttattt tagcaaatac
    12661 aaaatccata attattgaac caaatataaa tccatatgta aaaaatgata ctataaacgc
    12721 agaaaaactc ttactcacac cataaacgtc cattatgtat cttactcccc acaagcttat
    12781 aaatgcactt gtaagaccca caaaagagaa cattatcatt gaattatacc atgttgattt
    12841 gttctttata acagacttaa taccatcaac aatattaacc ttctctgact tttcataggg
    12901 ttcagtatct atattgaatc catactcttt tggtgtatct ctaacaataa tatacataaa
    12961 acatccaatt acaacaccaa ttataccgat taataaaaat gaatttctcc aaccaacaag
    13021 ttcagacaaa aacacaagtg gaaaagtagc aagaactcca cctaaatttc ctacaaatga
    13081 aaatttagct gttgcagaag caaattctga cttattaaac catctccctt gaatttttaa
    13141 aatacaaagt aatattactg atgttcctgc ccctacaatt acacgagaaa tatatgctaa
    13201 ttctatactt tgaatcaaac caaataaaat tgaccctaaa cttgccatta ttattccaag
    13261 actgctaatt tttcttgctc catatttatc aatcaaaatt cctgcaggta tttgcataaa
    13321 tgcatatgca tataggcaaa aggatgctat atttgaaatt tgtatagaat taaaacctaa
    13381 ctcatttgct aaattgtctg aaacaacagc agttgacatc cttaaaaata atactaaaac
    13441 aaatgaaaat gtaattatac cccaaacact ccacttagcc tttgtataac ttttcatatc
    13501 ttctccctca aatccatata tttttaaatt ttcttgatat aacttatata aagtgtatag
    13561 ttattcttac aaatttttac acgcaatatc attatacaac atatgtatat atttaactag
    13621 aaataaaaca ctattcatat tatatacatg aattaactac ataaataata agagccatct
    13681 tttaacatta ctcaaaagat ggctccatat aaaaacattt attctaaatt taatttttta
    13741 tctaatataa attttgtagc gaaaaataac gctattgcaa ctacaagact accaagtatt
    13801 gcaagcataa aactaggact ctgataaaga tgatatacca tatttgtatc ttcatttggt
    13861 aagatgcttc caactgcatc tccaacaatt gatattacta tatttatagc tataaaagaa
    13921 gcaaatgcca ctatgtttct atgtttattg aattttggta attgtcccat tgagattgat
    13981 gtatataata acaaaataaa tgatgaatat gaaataaaca ttactactac taataataaa
    14041 atatctaaaa agttttcaga aatccattta aaactagtgt taaacaaatc taaaatttca
    14101 ggtagtaaaa ttccagaagt accaaaaagc ataagaactc caaaagtgaa tactgcaact
    14161 ataaaactaa gtacagcgta tataagtgct gttatacatt tagataatat aagtgaacta
    14221 gtgctaacag gaagagtaaa cattaaataa ccttcatccc ccaaaagatt ttttctaaac
    14281 ctttgaattg taactacaat agttaaaact cctaatgcca taaaaagact tgttaatact
    14341 agtattccta ttccctgtac ctgaagtata tttgtattca taaatattcc gttaaataca
    14401 gctactatca atatggctat atataacggt ataaatattc ttccacttgc ttttaactca
    14461 tattttaata atttacctaa catttaaatt cctccctaaa taatgcatct atagattttc
    14521 ctttttcttc tcttattgct tcaacgtctc cttgtaacac tatttctcct tttgatatga
    14581 atattatctc atcacatatg ttttctattt cacttattaa atgggtagca atcagtaaag
    14641 tactatcttc agaataattt tttaatatag tcttaagtat atatgacctt gcagctgggt
    14701 caacaccacc tataggttca tccaatatat atatgctcgc atttcttgac attactaaaa
    14761 taagttgaac tttttcttta gttcctttag acattgtctt tagcttttca tttacatcaa
    14821 tatctaagct tttaatcatc tcatttgctc ttctaacatc aaaatcacta taaaaatcat
    14881 agaaaaactt aagtaaatct gataccttca tccaatcatt taaataagtt ctttctggta
    14941 aatatgaaac tattttttta gtatctatgg atggtttcat tccatttatc ataatttcac
    15001 cattatcagg ctgtaataat ccattcatta gcttaatcat tgtacttttg ccacttccat
    15061 taggtcctaa cagcccgact atttttccct ttggtatatt taaatcaata ttttttaaaa
    15121 cattcttagt tccataactc ttgtttacac ctttaaattc aactattcca tcttgagaaa
    15181 cattgcttat atttttatcc attttataat tctcctttca gattttctgt aataagtttt
    15241 agcatttcat ctctatcata tccaagcttt tctaaggtta cttttaatgt atttatctcc
    15301 acattagcta tttcctcttt catagctttt attttttcct tatcatctgt tacaaatctt
    15361 cctttagttc tctgactata aactaaacct tgtctttcaa gttctgttag agccttttgc
    15421 attgtatttg gattaacttc cgcatcttct gctagtgctc tcactgtttc taatttagat
    15481 cctattttaa tttcccctga aattattttt aactttaaat gttctactaa ttgtatatat
    15541 ataggtttgt tattatcaag ttcccattcc atgttcatgc ctccttatta tattattgta
    15601 ttaagttgtt aatacaataa tataataata caaagtatat gtcaattact ttttagtaaa
    15661 agtataaaaa attttacaaa aaaaatgaac actacattag agtccatttt taacacaatt
    15721 tattaaattc tttatattac agattaatta ccctcttacc aagttagata caattaaatg
    15781 ttcaaattct tcaattggca ttggctttcc aaacaaatat ccttgtgcca tatcacactt
    15841 tacttctttt aaaagtttaa actgttcttc tgtctcaact ccttctgata tgactttcat
    15901 acccaactct tttgccattt ctattacttt agtaacaatt attttgcttc ttttactatt
    15961 ataagtttcc ataataaatt tttggtcaag ttttaagata tccataggaa tttcttttaa
    16021 catatttaat gatgagtacc ctgagccaaa atcatccata gatattaaaa atcctatttt
    16081 ttttaaatta ttcattatat caattaaaat atcaaaatta tcaaatatga tactctccgt
    16141 taattcaagt tctatatact ttgcaggtat attgtattta tcaattatat ttttgtatgt
    16201 ttctataaaa ttattgcaat ataaatgtat ccttgaaaca ttaactgaaa cagtaactgg
    16261 atttattcct gcatcaatcc attttctaag gtatatacat acttcttcaa gcacatataa
    16321 atctaaattt ataacaaaac cgtttctttc aaaaaatggg ataaattcat ttggaggtat
    16381 tagcccttta tcaggacgtt tccacctaac aagtgcttct gaaccttgta tctctcctgt
    16441 attaagttct atcttaggtt gtaagtatat aataaattct ttattttcta gacttgaaaa
    16501 cattgtattt tccatctctt tttcttttat ctcttggtca tgaatcttat tatcataaaa
    16561 tgcatatgaa cttttatgtc ctccctttgc cattttatga ggtatattag ccctatctat
    16621 gattgagttg atatctctat cttctggaag tataaaatag attccacaac ttaaaactaa
    16681 cttatatttt tcttcttgat tattattaaa caagtctaat tcttcaaata tagtttttaa
    16741 cctctttgtt atatcttctt cttctatata tttcataatt ataataaaat tatccgcaga
    16801 tattcttgca aacatttcct cttcaaatat attcctctta ataatctttg ttaaattacg
    16861 caaaatttca ttcccaactt catatccaaa taaatcattt atatatttaa atttatcaat
    16921 atctatatat aataaagcat actttacttg agtattttta catagtattt tgttagcatc
    16981 aattacaaat ttatctatag tatttgctcc tgtaagatta tctgtatatg ctatcctttg
    17041 caatttaatt ttaaaattta atttatcata tattatatag aatataagta ttacacatat
    17101 tatagccata ataagtatta tttgtattgc atgtttgcta ataagctgat tattagacac
    17161 aatagactca aagttattta tggagttgtt tttatagagt ttgcataaag aatagactgg
    17221 tgttgtgtat gtaatttgta aaattataca aataaataaa aaaaacatca attttttttg
    17281 taaattcctc ataaaaattt cctcccatta aaacacctct attttattag caaataagta
    17341 catctcaaaa gtttccattt cttgtaaaat ggatagttta tatctacttt aattttgtaa
    17401 aattt
//
LOCUS       DAEPKC010000084        17356 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.084, whole genome shotgun sequence.
ACCESSION   DAEPKC010000084 DAEPKC010000000
VERSION     DAEPKC010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17356)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17356)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17356
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.084"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..927
                     /locus_tag="KR294_002816"
     CDS             <1..927
                     /locus_tag="KR294_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3810 domain-containing protein"
                     /protein_id="HBH0240879.1"
                     /translation="ISIFLFLCCTLSTIFNKKKKLNIYLKNSILNILSIVSIVYFLFV
                     VLWGINYNRIPLETTLINNYNLKNNTSIQSKQYSVKELTKLYKFLVIKANETRKLTLQ
                     DKNGIVKSNTDYNGVINRAQLGYDNILDILPGVSGSYSKPKYIISSNLMCYTGITGIY
                     FPFTGEANVNIAIPDLYIPCTVEHEMAHQRGFASEDEANFIAYLTSIKHPNIDFNYSG
                     YILALNYTASALSKVDYNAYVDISAGISDSVRRDLKNESEFWQKYEGKINEISNEFNN
                     SYLKANSVTEGTQSYGKMVDLLLTYYELYPYN"
     gene            complement(1401..2225)
                     /locus_tag="KR294_002817"
     CDS             complement(1401..2225)
                     /locus_tag="KR294_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240880.1"
                     /translation="MRYKKISSLPILVVALLITGTTTTFSLSTTNSEKTNVYLANTVS
                     TVTKKVSDIQSSKGLVYNENIPLFINNSKIQYDDTPYHWPSNVISLTNSSEKAIMDYE
                     ITCLAYDKNGKPLELYWDAQNVAADGEVGSVGFSPAGVDYGIVTGISPVSPKSYSHTY
                     RKMQQSPPQDIISMFEKQQGKAWVENWLKEWKQMEKEYAKQNAIAPGKNQNDAFLLFD
                     KWKQSTGEHGVKYIISCVKQVTFNDGSVWKNSAYENWLKSFQGKEVSNSVLENYYK"
     gene            complement(2573..3628)
                     /gene="ispG"
                     /locus_tag="KR294_002818"
                     /gene_synonym="gcpE"
     CDS             complement(2573..3628)
                     /gene="ispG"
                     /locus_tag="KR294_002818"
                     /gene_synonym="gcpE"
                     /EC_number="1.17.7.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin-dependent
                     (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase"
                     /protein_id="HBH0240881.1"
                     /translation="MSYERRKTREVSVGTVKIGGENPISIQSMTNTDTRDADATIAQI
                     KRLEEAGCDIVRVAVPDIKAAKNIAKIKSSVNIPIIADIHFDYKLALEAIEQGVDGIR
                     INPGNIGSIERVKMVVEKCKERNLKIRIGVNGGSLEKELLKKYGSATAEALVESAMGH
                     IKILEDLDFHNIVISLKSSDIYKTVDAYELISKKVDYPLHIGITESGSVHKGTIKSSI
                     GVGALLLKGIGDTVRISLTGDPVEEVIVGKQILRSLGLLNDKIKVISCPTCGRCNIDL
                     ISVVNEVEEKIGSMEKNITVAIMGCAVNGPGEAREADIGIAGGKGEGLLFKKGEIVRM
                     IDGNKLVDELLEEIEKL"
     gene            complement(3810..4814)
                     /gene="rseP"
                     /locus_tag="KR294_002819"
     CDS             complement(3810..4814)
                     /gene="rseP"
                     /locus_tag="KR294_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HBH0240882.1"
                     /translation="MTIIAALILFSIIVLIHELGHFIFAKRSGIKVNEFSIGMGPKIY
                     SVKKDTEYSIRALPIGGYVSMEGEDEEQISPNSFGNKSILQRFSTIVAGPIFNIILAA
                     ILLVPVFLYIGSPTTKLGKIMPDTPAQAVGLQVGDKINKINGNSVKTWDEVANIINTS
                     SGGELKLSITRDGSDKVVNVTPKNNNGKYEIGIQPQREKDFLGSIVNACKTTVDMTKQ
                     MLTFLGQMITGRVPGGIGNAVAGPVGVIGMVSDAARTGIINVVYLAAVISLNLGIVNL
                     LPIPALDGWRILMLLLEAVRGGKKLDPNKEGMINVVGFGALMLFMLFITYKDILRLFQ
                     "
     gene            complement(4827..5981)
                     /locus_tag="KR294_002820"
     CDS             complement(4827..5981)
                     /locus_tag="KR294_002820"
                     /EC_number="1.1.1.267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate reductoisomerase"
                     /protein_id="HBH0240883.1"
                     /translation="MKKISILGSTGSIGKQTLDVVRDNRDKFEIVAISANSNIELLLE
                     QIVEFKPKYVTVFEENKALKLKEMLPKNIEIEVLAGMEGLKIISSLDEVDVLLTAVVG
                     MIGLVPTLCAIKKGIDIALANKETLVTAGELVMKEAEKYNVNILPVDSEHSAIFQCLN
                     GENKKNIEKIILTASGGPFRGKKKGELANITKNEALKHPNWSMGRKISIDSSTLMNKG
                     LEVIEARWLFGVEQENIDVVVHPQSIIHSMVQYTDSSIIAQLGCPDMRLPIQYALTYP
                     DRMESSFERMNFSKFSTLTFEEPDLETFPCLKLAYECLKMGGTYSSVLNSANEVLVSE
                     FLEDKIGFYDIPYYIEKTLEVHSSISEPTLEEILETDRWSRAYVANLIKK"
     gene            complement(6145..6348)
                     /locus_tag="KR294_002821"
     CDS             complement(6145..6348)
                     /locus_tag="KR294_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH0240884.1"
                     /translation="MISYAPLWKLLIDRKIKKMEFVNISGISISVLGRLGNDKSVSMD
                     TMEKICLALDCKIEDVVEIKKSI"
     gene            6685..7266
                     /locus_tag="KR294_002822"
     CDS             6685..7266
                     /locus_tag="KR294_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240885.1"
                     /translation="MLYLLKINQFEKSYDIGIFKNEQSIYKFIAKIPFVKKDNSNFNY
                     TNYYMEFEDIPEYYEVNFNNYLYIITRFSFIPDGTEIFFTWEEIHCWDEKVATEKTFI
                     NGETLVDSYNFPNNEVKDYIQKRESLYIETKKYYEEKGLKIERHALGSEDGEYVELTN
                     DSILYLLDIEAVEIREQSKNIEEFLYKYKKRFK"
     gene            complement(7354..9165)
                     /locus_tag="KR294_002823"
     CDS             complement(7354..9165)
                     /locus_tag="KR294_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HBH0240886.1"
                     /translation="MKKKYDFLIYSAIWLVIIILFIFSLYHSIEHIKIISHTGTIRSE
                     TQKVVKQELNNERNDDLIKRLDNILIKLRTGNGENGFQRCDNKEFQQKLNQMDSMWES
                     MKKEIIKVRNGASGDKLYKLSEEYSVLSNQIVFISEKHSNAKLYSFATALFIYLIFST
                     ISLLIWEYYNKKRFKRIFYTDNLTKIKNQVAFENRAIEILHNASNKEYVLLNIDIDNF
                     KYINDTHGYEYGDKVLIIVAAALSKTFNIKETCARIGSDNFVILAKYRDSLLEDIREM
                     LTNAIISELDMNVTQTISYCIGAYLVEIDNLGYKSINSIMDKANIAHKVSKTRGISST
                     VWYNENLLKQLQMENSIYNYMYKAIENEEFHMYLQPKFQISSLNVVSAEALVRWFSPE
                     LGFLSPDEFIPLFEKSGFIIELDFYMLKKACSFVRKTFMKKNQYTYPIAVNFSRVTIY
                     QNSFYQRFLDTVKEYEIPFKYIEIEVTESAFNEISQPVISILEELKKLGFLISMDDFG
                     SGYSSLSLLCSLSINGLKLDKSLLKETFNREKVYSIIQCIIEMSHRIGMSVVCEGIET
                     KKDLEFLNTVKCDVGQGFYFSKPIEEKEFFNKYVTKK"
     gene            complement(9989..10768)
                     /locus_tag="KR294_002824"
     CDS             complement(9989..10768)
                     /locus_tag="KR294_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HBH0240887.1"
                     /translation="MLTRIIASLALVPLFLFVVYGGIPLYIAETAIVYIALHEFYKAF
                     KIKDVHPIFIIGYLFSIYLAVKNIFNLPLEYTYAVIFILFLASIIYMLMGKNNVIDVS
                     ITFLGVFYIGVFLDFIIITINGFEKGSIYVWLIFVISFMTDIFAYFSGYLLGKHKLIP
                     KVSPKKTIEGAIGGIIGSTLCCILFGYLFGIDLLQLAIIGSIGSVIAQLGDLFASSIK
                     RYVGIKDYGKIIPGHGGILDRFDSVILVAPFVYSAIKFFIR"
     gene            complement(10781..11515)
                     /locus_tag="KR294_002825"
     CDS             complement(10781..11515)
                     /locus_tag="KR294_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HBH0240888.1"
                     /translation="MNNNIIYDIDLNNIPTHIAIIMDGNGRWAKARFLPRTAGHKAGV
                     ETIRDIVKECSKLGVKHLTLYAFSTENWKRPKLEVDTLMNLLSTYLRNEIAELHQNNV
                     KVTAIGDISALPKTCIRELNSAKELTKNNTGVNLNLALNYGSRADIKNALIDIVKNCE
                     SGKIDINNIDEDIIKNYLSTKSIPDPDLVIRTSGEQRLSNFLLWEVAYSEFYFTDIHW
                     PDFKKEELQKAIYVYQRRDRRFGGLK"
     gene            complement(11544..11747)
                     /locus_tag="KR294_002826"
     CDS             complement(11544..11747)
                     /locus_tag="KR294_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240889.1"
                     /translation="MKKYYNLLGLHVDEVKQYFDEQNINYTVKSIEGKKDKEKLVVPR
                     VIKISEIGDSVELIITYFSDSLV"
     gene            complement(11750..12307)
                     /gene="frr"
                     /locus_tag="KR294_002827"
     CDS             complement(11750..12307)
                     /gene="frr"
                     /locus_tag="KR294_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HBH0240890.1"
                     /translation="MKLEIHKQLEEKMNGTIDALKFEFGTIRAGRANAQMLDKIRVDY
                     YGTPTPINQIGAISVPEPRILMISPWDKSAMHEIEKAIANSDLGLNPSNDGEVIRLSV
                     PALTEERRKELAKKASKAAEEFKVRIRNERRDANEKIKKMEKGGELTEDELKKAQDEV
                     QKMTDKFIKEIDTLLSKKEKDIMEV"
     gene            complement(12333..13037)
                     /locus_tag="KR294_002828"
     CDS             complement(12333..13037)
                     /locus_tag="KR294_002828"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HBH0240891.1"
                     /translation="MDKPMYKRVLLKLSGEALAGERGFGINNDVVNDIAIAIKKIQEI
                     GVEVAVVVGGGNFWRGRTSEGMDRTTADYIGMLATVMNAMALQDALENIDVATRVQTA
                     IDMRQIAEPYIRRRAVRHLEKERVVIFGAGTGNPYFTTDTTAALRAAEMEAEVILLAK
                     NVDAVYDKDPKVHADAKKFTELSYMEVIQKELKVMDSTATSLCMDNKIPIKVFELTTE
                     NIIRAVKGENIGTTVK"
     gene            complement(13122..14033)
                     /locus_tag="KR294_002829"
     CDS             complement(13122..14033)
                     /locus_tag="KR294_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HBH0240892.1"
                     /translation="MANITAQMVKELRESTGAGMMDCKKALQEAEGNMEKAVDLLREK
                     GLSKAAKKAGRVAAEGLVAIEMNDDNTVASMVEVNSETDFVAKNEDFKVFVKDAACMA
                     LATDKEDIASLLGETHKEGITLQEVLNNRVAKIGEKLDFRRFAKVVTNGQVAGYIHGG
                     GKIGVLVEMETEARDAKVLELGKDVAMQVAAMNPKYVSRDEVDAEYIAHETEVLTQQA
                     LNEGKPANIVEKMVKGRLEKELKEVCLLEQTFVKNPDITVKQLVADVAKAVGSDIKVV
                     KVVRFEVGEGIQKREENFAEEVAKQLK"
     gene            complement(14112..14825)
                     /gene="rpsB"
                     /locus_tag="KR294_002830"
     CDS             complement(14112..14825)
                     /gene="rpsB"
                     /locus_tag="KR294_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HBH0240893.1"
                     /translation="MSVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIYIIDLQ
                     KTVKKVEEAYKFTKEVAETGKPILFVGTKKQAQDAIKDEAERCGMYFVNERWLGGMLT
                     NHKTIKTRINKLRELEKMEEEGVFNVLPKKEVIKLRAEKEKLEKYLGGIKDMPELPGA
                     MFVVDPRKENIAIQEAHRLGIPVVGIVDTNCDPEQLDFAIPGNDDAIRAVKLITGAMA
                     TAVIEGRQGAEEEVAEDQE"
     gene            complement(15032..16216)
                     /locus_tag="KR294_002831"
     CDS             complement(15032..16216)
                     /locus_tag="KR294_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HBH0240894.1"
                     /translation="MKNALKKIISLAMILVFIIPNYSYADDKSVDKYSKTSILIDQET
                     GRVLYSKEPDMKVPLASLSKMMTFLLAIEAIENKEVKETDKVKIDKSIASVKGSSYKL
                     KDGEEVPLIELMRGLMIVSGNDAAIAIAKHVCKTKEAFVDRMNKKAKEIGMSNTHFLN
                     PNGLPIYDLSNPKKPAKENISTAKDIAILGKYMFDHYEKQVTAITDMETYTNSDRSFE
                     KSNTNALLRIIPEVDGIKTGYTGNAGYCLSFSMVVNKNDKNEKKRRVIGVVLGTNHKN
                     KRTSASLALLKYGKENFNMKKVIDKDSFIGKKYIKGTKELEVTLKAKDELYTILKDDE
                     SIKSEVKIKNIEYPVKKGDTMGIIKYYTNSGDLLGSVDIVSNNSIDNVSLKTKLKMKF
                     AN"
     gene            complement(16320..>17356)
                     /locus_tag="KR294_002832"
     CDS             complement(16320..>17356)
                     /locus_tag="KR294_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="potassium channel family protein"
                     /protein_id="HBH0240895.1"
                     /translation="IDERKKCHREADSSGYCIFHKENKSDEEIQLMMDTLHKEEISEF
                     NGFVFENEFNAEEILTYNYKILDFSESIFKQKANFKKYIFKKNIIFNYTEFRDKVLFN
                     GCVFLENCDFNRTIFSKHYINDRIFEKVKFKGPDLVVNKVENFPRMDGIIFSMCTKFV
                     LKNVEYGKSEYEHGKINYRIARNQATKIGEYEMIGFYYYKERIYSSKIMKRSNYPTFS
                     DYLVEKFFDQIARYTTGYGEKPWNILLVIIAIISVFALLYLFVGIESSNSTLVALDIN
                     NIGDYSLSEIFKMYMDLWYFSMATFSTVGYGDMVATSLIGKALAGIEVFFGVTIGAIW
                     ASVIIKRMIR"
BASE COUNT         5659 a         3037 c         1770 g         6890 t
ORIGIN      
        1 atatctatct tcttattttt atgttgtact ttatctacaa tttttaataa gaaaaaaaaa
       61 ttaaacatat atttaaaaaa ttccatttta aatatattat ccattgtatc aatagtctac
      121 tttctttttg tagtgctttg gggaataaac tataatagga ttccactaga aaccacactt
      181 ataaataact ataatttaaa aaacaatacc tctatccaat caaaacaata tagtgttaaa
      241 gagcttacta aattatataa attccttgta attaaagcaa atgaaactag aaaactcaca
      301 ttacaagata aaaatggtat tgtaaaatct aatacagatt ataatggtgt cataaataga
      361 gctcaactag gatacgataa tatcttggat atattacctg gtgttagtgg tagttattct
      421 aagcctaagt atattatttc atcaaatcta atgtgctata caggaataac tggtatatac
      481 tttcctttta caggtgaggc aaatgtaaat atagcaatac ctgacttata tattccttgt
      541 acagttgaac atgaaatggc acatcaaagg ggatttgcta gtgaagatga ggctaatttt
      601 atagcgtatc ttacttctat aaaacacccc aatattgatt ttaactattc tggatatatt
      661 ttagctttaa attatactgc ttctgcttta agtaaggttg attataatgc atatgttgat
      721 atttctgctg gcatttcaga ttctgtccgt agagatttaa aaaatgaaag tgaattttgg
      781 caaaaatatg aaggtaaaat taatgaaatt tctaatgagt ttaacaattc ttacttaaaa
      841 gctaatagcg ttactgaagg tactcagagt tatggtaaaa tggttgattt attgctaact
      901 tattatgaat tatatccata taactaaaca ctacaattca aaattttatt catatacagc
      961 tgatattaaa tcagctgttt tctatttaaa taaattattt aacttcaagc aatcttatat
     1021 aatttgatag tacttatact atctgtataa catttcaatt ctaactattt tagttaaaac
     1081 atttctatta tcttttttaa taaatgtttt aactaaaatt tttaaaacat aaaacttcca
     1141 cattatttca ctatctatat aaaaatctaa aaattcacat ataaaattac ataactaaaa
     1201 aatcataaat ttatagaaaa catatattca aaataaaaaa gcatgtatca aaacttgaca
     1261 catgcttata atcttatgta tatatatcat tttgtcacaa taaaaattta cttgtaacac
     1321 tgatattttt aaacaaaata gtccttattt aattaaatta acattaatta aattcgtact
     1381 cattttgcta tcattaaaca ttacttatag taattttcta atacactatt tgaaacttcc
     1441 ttcccttgaa aacttttcaa ccaattctca tatgctgagt ttttccatac actaccatca
     1501 ttaaatgtta cttgttttac acaagatata atgtacttta caccatgctc tccagttgat
     1561 tgtttccatt tatcaaacaa tagaaaggca tcattttgat tcttacctgg tgctattgca
     1621 ttttgctttg catattcttt ctccatttgt ttccattctt tcaaccaatt ttctacccat
     1681 gccttgcctt gttgtttttc aaacatactt attatatcct gtggtggtga ttgttgcatt
     1741 tttctataag tatgtgaata tgattttgga gacacaggag atatgcctgt aacaatacca
     1801 tagtctacac cagctgggct aaatccaaca cttcctactt cgccatctgc tgccacattt
     1861 tgagcatccc aatatagctc aagtggtttt ccatttttat catatgctaa gcatgtaatt
     1921 tcataatcca taattgcctt ttcactgcta tttgttaagc ttataacatt gctaggccaa
     1981 tgatatggag tatcatcata ctgtattttg ctattattta taaataatgg aatattctca
     2041 ttataaacaa gacctttact actttgaata tctgatacct tctttgtgac agtacttacc
     2101 gtatttgcta agtatacatt tgttttttct gaattggtcg tactaagaga aaatgttgtt
     2161 gtcgttccag taatcagcaa agcaacaact aaaataggta agctagatat ttttttatat
     2221 ctcacaattc ttcacctctt tttctattaa cttataataa aacaatttac caaaacatta
     2281 aaatctatgt taacataatt taccaactgt tctagtaact atatcctatc atagttacta
     2341 tcaagtttca atactattga tggaaatttt cactatatta aatctttttt taattttata
     2401 aatttacaat atgatttaac tcatacatat atagtcaaat tagaatataa gtttcttaca
     2461 tttaatgaag tttataaaat aaaaaatgac tagataatta aatactgtaa ataaaaactt
     2521 attacaaaag tatttaaaaa tctagtcaat taatatatat atgaattgta tactataatt
     2581 tttcaatctc ttctagcaac tcatcaacta atttgttacc atcaatcatt ctaactattt
     2641 cacccttttt aaataaaaga ccttcacctt tacccccagc aatacctata tctgcctctc
     2701 tggcttcacc aggtccattt acagcacagc ccataattgc aacagtgata tttttttcca
     2761 tactaccaat cttttcttca acctcattta caacactaat taagtctata ttacatctac
     2821 cacatgtagg gcatgatata actttaatct tatcatttaa aagtcccaaa cttcttaaaa
     2881 tctgtttacc aacaataacc tcttcaacag ggtcgcctgt taaagatatt ctaacagtat
     2941 ctccaattcc tttaagaaga agtgctccta cccctataga agactttatt gttcctttgt
     3001 gaacacttcc agattctgta attccaatat gaagaggata atcaactttt tttgatatta
     3061 attcatatgc atcaacagtt ttataaatat cggatgattt tagagatata actatattat
     3121 gaaaatctaa gtcttcaaga atcttaatat gtcccattgc actttcaact aatgcttcag
     3181 cagttgcaga gccatacttt tttaaaagtt ctttctctaa agaacctcca ttaactccaa
     3241 ttctaatttt taaatttctt tccttgcatt tctcaactac catcttaact ctctctatac
     3301 ttccaatatt accaggattt attcttattc catccacacc ttgttctata gcttcaaggg
     3361 ctagcttata atcgaaatgt atatctgcaa taattggtat atttacacta gactttatct
     3421 ttgctatatt tttagcagct ttaatatcag gaacagcaac tctaactata tcacaaccag
     3481 cttcctctaa tctctttatt tgagctattg tagcatctgc atctcttgta tcagtatttg
     3541 tcatagattg tatacttata ggattttctc ctcctatttt tacagttcct acacttactt
     3601 ctctcgtctt tcttctctcg taactcatat tccacctcta tatattattt tatattgaat
     3661 ctctttaaat attaaaatat tataacctac atgtatatta taaattaaaa agctatctag
     3721 ttaaataaga ataaatttca tatataaaaa ttaatttatt cttatttaaa actacatagc
     3781 ctattttctt aaaatctcta aaaactaaat cattgaaata atcttagtat atctttatat
     3841 gtgataaaaa gcataaataa cattaaagct ccaaaaccaa caacatttat catgccttct
     3901 ttatttgggt cgagtttttt accacctcta acagcttcta gtaacagcat aagtattctc
     3961 catccatcaa gtgctggtat tggtaataga tttactatac ctaaatttaa gcttatgaca
     4021 gctgctaaat acactacatt tatgatgcct gtacgagcag catctgatac cataccaata
     4081 acacctactg gtcctgctac agcattgcca atccctcctg gtacacgtcc tgtaatcatt
     4141 tgacctagaa atgttagcat ctgttttgtc atatctacag tagttttaca tgcatttact
     4201 attgacccca aaaagtcttt ttctctttgt ggttgaatcc ctatttcata ctttccattg
     4261 ttatttttag gtgttacatt tacaacttta tcacttccat ctctagttat actaagtttt
     4321 aattctccac cagaagaagt atttattata tttgcaactt catcccaagt cttaacagaa
     4381 ttaccattaa ttttatttat cttatctcct acttgaagcc ctacagcctg tgcaggagta
     4441 tctggcatta tctttcctaa tttagtcgtt ggagaaccta tatacaaaaa tactggaact
     4501 aaaagtattg ctgctaatat tatattgaat attggtcctg ctacaatagt actaaatctt
     4561 tgtaatatag acttgtttcc aaaagaattt ggacttattt gttcttcatc ttcaccttcc
     4621 atgctgacat atccaccaat tggaagtgct cttatagaat actctgtatc tttttttaca
     4681 ctatatatct taggccccat acctatagaa aactcattta ctttgatacc acttcttttt
     4741 gcaaatataa aatgtcctaa ctcatgtatt aatacaatta tactaaatag tattaatgcg
     4801 gctattatag tcataaattc accttcctat ttttttatca gatttgcaac ataagctcta
     4861 ctccatctat ctgtttctaa gatttcttct aatgttggtt cacttatgct actatgaact
     4921 tctaaagtct tctctatgta atatggtatg tcatagaaac caattttatc ctctaaaaat
     4981 tcacttacta aaacttcatt tgctgaattt aaaacagagg aataagttcc tcccattttt
     5041 aaacactcat atgccaattt taaacatgga aaagtttcta aatctggttc ttcaaaagtt
     5101 aaagtactaa attttgaaaa attcattctt tcaaagctac tttccattct atctggatat
     5161 gtaagagcat actgtattgg tagtctcata tctggacatc ctaattgagc aattattgag
     5221 ctatctgtat actgcaccat tgaatgaatt atgctttgtg ggtgaactac tacatctata
     5281 ttttcttgtt ctactccaaa taaccatcta gcttctatca cttcaagtcc tttattcata
     5341 agcgttgaag aatcaatact tatttttctt cccatactcc aatttggatg cttcaaagct
     5401 tcatttttag ttatatttgc aagttctccc tttttctttc ctctaaatgg accaccagat
     5461 gctgtaagta ttatcttttc tatatttttt ttattttctc catttagaca ttgaaatata
     5521 gcactatgtt cactatcaac aggaagaata tttacattgt atttttctgc ttctttcatt
     5581 acaagttcac cagcagttac caacgtttct ttattcgcta atgctatgtc tattcccttc
     5641 tttatagcac aaagagttgg gactaatcct atcataccta ctacagcagt taaaaggaca
     5701 tccacttcat caagtgatga tattattttt aatccttcca ttcctgctaa aacttctatt
     5761 tctatatttt taggcaacat ttcttttaat ttcaatgctt tattttcctc aaaaactgtt
     5821 acatatttag gtttaaactc tactatctgt tctagcaata attcaatatt actgttagct
     5881 gatattgcaa ctatctcaaa cttatctcta ttatctctaa ctacatccaa agtttgttta
     5941 cctatagagc ctgtagaacc taaaattgat atctttttca tataataatc ctttctaata
     6001 ataaatatac cctgtcaaaa cattataaca ctactaaaac aattattttt actattcata
     6061 gaaatttcat atattattcc acagattaaa attaatctat tattttttgt attttgtgga
     6121 atattataaa atattctagt attattaaat gctctttttt atttccacaa catcttctat
     6181 tttacagtct agtgctaaac atatcttctc cattgtatcc atagaaacag atttatcatt
     6241 tcctagtctg cctaaaacag aaatacttat acctgatata tttacaaatt ccattttctt
     6301 tatttttctg tcaattaaca atttccataa tggagcgtat gaaatcatgt tatcacctcg
     6361 caaaatatat tctatcacat tttatctatt ttggaaaatt ttcatctatt tagataaata
     6421 attatttatc taaatagatt tcaattatag tttattaaat ataaatatgt taaaataaaa
     6481 caaaagcata agttcaaaaa ttaaacttta tatatattta tctcattatt ttactaaaac
     6541 ataactatat aaaaaatatt tactattata tatctattta aaacacatta ttatagtatc
     6601 atataaacat atgtaaatat ataattaaaa aagctaaaga ttagtaaatt tataaaaatt
     6661 atattttgaa taaaaggaga aagaatgttg tatttattaa aaattaatca atttgaaaaa
     6721 agttatgata taggaatttt taaaaatgaa caatcaatat ataaatttat tgcaaaaata
     6781 ccctttgtaa aaaaagataa tagtaatttt aattatacaa attactatat ggaatttgaa
     6841 gatattcctg aatattatga agtaaatttc aataattatt tatatattat taccaggttt
     6901 tcattcattc cagatggaac tgagatattt tttacttggg aagaaatcca ttgttgggat
     6961 gaaaaagttg ctaccgagaa aacttttata aatggcgaaa cattagtgga ttcatataac
     7021 tttccaaata atgaagtgaa agactacata caaaagcgag aatcattata tatagaaaca
     7081 aaaaaatatt atgaagaaaa aggattaaaa attgagagac atgcactcgg ttcagaagat
     7141 ggtgaatatg ttgaacttac aaatgattct atactttatt tactagatat agaagcagtt
     7201 gaaataagag aacaatcaaa aaatatagaa gaatttctat ataagtataa aaaacgtttt
     7261 aaataattta tattttaaaa tacataacag tacattgagt catttaacga gatataaaat
     7321 gactcaatgt atagactgat aaaaataatt atattatttt ttagttacat atttgttaaa
     7381 aaattctttt tcttctatcg gtttagaaaa ataaaaccct tgtcctacat cacatttaac
     7441 tgtatttaaa aattccaagt cttttttagt ttcaatacct tcacatacaa cagacatgcc
     7501 tatacgatgt gacatttcaa taatacattg aataatacta tatactttct cccggttaaa
     7561 ggtttcttta agtaagcttt tatctaactt caatccatta atagatagag aacataaaag
     7621 acttaatgaa gagtatcctg aaccaaaatc atccattgaa attaaaaatc ctaacttttt
     7681 aagttcctct aaaattgaaa taactggttg agatatttca ttaaaagcac tttcagttac
     7741 ctctatctct atatacttaa aaggaatttc atattcttta acagtatcta aaaacctttg
     7801 ataaaaacta ttttggtaaa tagtaaccct tgaaaaatta actgcaatcg gatatgtata
     7861 ttgatttttt ttcataaacg tttttcttac aaatgaacac gcttttttta acatataaaa
     7921 gtccaattca ataataaatc cacttttttc aaacaatgga ataaattcat ctggtgataa
     7981 aaaaccaagt tctggagaaa accatcttac aagagcttct gcgcttacaa catttaaaga
     8041 agatatttga aatttaggtt gcaaatacat atgaaattct tcattttcta tcgctttata
     8101 catataatta taaatactat tttccatttg taactgtttt aacagatttt cattatacca
     8161 tactgtggag gaaattcctc ttgttttact taccttgtgt gcaatatttg ccttatccat
     8221 tatagaattg atggatttat aacctaaatt atcaatttca actaagtacg ctcctataca
     8281 ataagatata gtttgagtta cattcatatc taattcagag attatagcat tagttagcat
     8341 ttcccgaata tcctctaaaa gagaatctct atattttgca agtattacaa aattatctga
     8401 accaattctt gcacaagttt ctttgatatt aaaagtttta gaaagtgcag ctgcaactat
     8461 tattagaact ttatctccat attcatatcc atgtgtatca ttaatatatt taaaattgtc
     8521 aatatcaata tttagcagta catactcttt gttagatgca ttgtgcaaaa tttcaatcgc
     8581 tctgttttca aatgcaacct gattttttat ttttgttaaa ttatcagtat aaaatattct
     8641 tttaaacctt tttttattat aatattccca aattaaaaga cttattgttg agaatataag
     8701 ataaataaat agtgcagtag caaaagaata caattttgca ttagagtgtt tttcagatat
     8761 aaaaacaatt tgattagaca acacagaata ctcttcactc aatttatata atttatcacc
     8821 tgaagcacca tttctaactt ttataatttc tttcttcata gattcccaca tagaatccat
     8881 ttgatttagt ttttgttgaa attctttatt atcacatctt tgaaatccat tttctccatt
     8941 acctgttctt agctttatca gaatattatc cagtcgtttt atcaagtcat catttctttc
     9001 attattcaat tcttgcttaa caaccttttg agtttcactg cgaatagtac cagtgtgact
     9061 tataatttta atatgctcta tactgtgata tagagaaaat ataaaaagaa taataataac
     9121 tagccaaata gcagaataaa ttaaaaaatc atattttttc ttcattattg ttacctcatt
     9181 tgtaatatat ataatttgca aataatcaat ctcttataaa aaatgattat caatatttta
     9241 cagtgatatg tatttatctt aaatagttta atcatttata tcctataaat tatacaaatt
     9301 catcacctcc aacacaaaca gcaatatacg tttttctaaa atttcttttt aaacattcat
     9361 caacactatc attaaatcat ttttaaattg ctcaattaat ttactgcatc acttcttttc
     9421 ttataaaata tcaccccaat aatatatttg tataatgtct ttatgtctct ttttaaattt
     9481 ggcatataca taatctatat tttaataaat aattaaaata ctatttacct acaatttaac
     9541 tctttgaatt tattttatca tattatgtaa atatattcct tttttttggt atattactta
     9601 aattatatct atttttgtgt aataagacca ataatttact tatttcttat taattatatt
     9661 taaaaataaa atttataaat ggataataaa ttagttacat ttatacatat atattataaa
     9721 tatataatat agctaaaaat atcgaaatta ttaaacaaaa aaatattttt taatgatagt
     9781 tatagtataa aaaatatact cactacaaat atagtatact attataaagt aatacctatt
     9841 cttatacaat tccccaaggt cttctaaatt tttgaacaat gaaaatagcc atgtaactaa
     9901 taactgcaga atatctctgc atttaaaagt tacatagcta ttttcattac tagcaattat
     9961 agattgctct tttaaatcca accaatcttt atctaataaa aaatttaatc gcactatata
    10021 caaaaggtgc aactaatata acactatcaa atctatctaa tataccccca tgaccaggta
    10081 ttatctttcc ataatccttt atccctacat atctctttat agaagatgca aataaatctc
    10141 ctaattgagc tattacactt cctatacttc ctattatcgc taattgaagc aaatcaatgc
    10201 caaataaata tccaaataaa atacaacaaa gtgtacttcc tattattcct ccaatagctc
    10261 cttctatagt ctttttagga ctaactttag gaattagctt atgttttcca agtaaataac
    10321 cactaaaata tgcaaatata tctgtcataa aagatatcac aaatataagc catacatata
    10381 tactaccttt ttcaaatcca tttatagtta taattataaa atctaaaaat actcctatat
    10441 aaaaaactcc taaaaacgta atcgaaacat ctataacatt gtttttgccc atcaacatat
    10501 aaattatact tgctaaaaat aaaataaaaa ttactgcata agtatattct aatggtaaat
    10561 taaaaatatt ttttacagct aaataaatag aaaataaata tcctataatg aatattggat
    10621 gtacatcttt tattttaaat gccttataaa actcatgcaa tgcaatataa actattgctg
    10681 tctcagctat atatagagga atacctccat atacaacaaa tagaaataat ggaaccagag
    10741 ctagtgaagc aataattctt gtaagcataa aataatctcc ttacttaagt cctccaaatc
    10801 ttctatccct tctttgatat acgtatatag ccttctgtag ttcttctttt ttaaaatcag
    10861 gccaatgtat atcagtaaag taaaactcag aataagcaac ttcccaaagt aaaaagttac
    10921 tcaatctttg ttcaccactt gttcttatta ccaagtctgg atctggtata gactttgtgc
    10981 ttaaatagtt ttttataata tcttcatcaa tattgtttat atctatttta ccactttcac
    11041 aattttttac tatatctata agagcatttt ttatatctgc tctacttccg tagtttaatg
    11101 ctaaatttaa gttaactcct gtattgtttt ttgtcagttc cttagctgag tttaattctc
    11161 ttatacaagt ttttggtaaa gcacttatat ctcctatagc agttactttt acattgtttt
    11221 ggtgaagttc agctatttca tttcttaagt atgtagataa taagttcata agtgtgtcaa
    11281 cttcaagttt cggtcttttc cagttttctg ttgaaaatgc atataatgtt aagtgcttaa
    11341 cacctaattt tgagcattct tttactatat ctcttatagt ttctactcca gccttatgtc
    11401 ctgcagttct tggaagaaat ctagcttttg cccatcttcc atttccatcc attataatag
    11461 caatatgagt aggtatgtta tttaagtcta tatcatatat aatgttgtta ttcatatttt
    11521 gcctccaata ttgttctgac tccttaaact aaggagtcag aaaagtatgt gattatcagt
    11581 tctacactat cacctatctc agatattttt ataactctag gaactacaag tttttcttta
    11641 tcctttttac cttcaataga ttttacggta taatttatat tttgctcatc aaaatattgt
    11701 tttacctcat ctacatgaag acctaaaagg ttataatatt ttttcaatat tatacctcca
    11761 ttatgtcctt ttctttttta gataataatg tatctatttc ttttataaat ttatcagtca
    11821 ttttttgaac ttcatcttgt gcttttttta attcatcttc agttaattct ccgccttttt
    11881 ccatcttttt aattttctca ttggcgtctc ttctttcatt tcttattcta actttaaatt
    11941 cttctgcagc tttactagct tttttagcta attcttttct tctttcttct gttaaagcag
    12001 gtacagaaag tcttataacc tcaccatcat ttgatggatt taatcctaag tctgagttag
    12061 ctatcgcttt ttctatttca tgcatagcag atttatccca aggagatatc attaatattc
    12121 ttggttctgg tacagatata gcacctattt gatttattgg agttggagtt ccataataat
    12181 caactcttat tttgtctagc atttgtgcat tagctcttcc tgctcttata gttccaaatt
    12241 caaactttaa agcatcaatt gtcccattca ttttctcttc taattgctta tgtatttcca
    12301 gtttcataat tttactcctc cttcattctt cattatttta cagtagttcc tatattttcg
    12361 ccttttactg ctcttattat attctctgtt gtaagctcaa atacctttat tggaatttta
    12421 ttatccatac ataaagatgt agctgtagaa tccattactt ttaattcttt ctgtataact
    12481 tccatgtaac ttaattctgt aaatttctta gcatctgcat gtacttttgg atccttgtca
    12541 tatactgcat caacattttt agctaacaat ataacttctg cttccatctc agcagcacgt
    12601 aaagcagcag ttgtatctgt tgtaaagtaa gggtttcctg ttcctgcacc aaatataaca
    12661 actctttcct tttctaagtg tctaactgct cttcttctta tatatggttc tgcaatttgt
    12721 ctcatgtcta tagcagtttg aactcttgta gcaacatcta tattttctag tgcatcctgt
    12781 agcgccattg cattcataac tgtagctaac attcctatat agtcagcagt agttctgtcc
    12841 attccttcac tggttctgcc tctccagaag tttcctccac ctactactac agctacttca
    12901 acacctattt cttgtatttt ttttatagca atagcaatat cattaactac atcattattt
    12961 ataccaaaac ctctttctcc tgctaatgct tctccactta attttaacaa tacccttttg
    13021 tacattggtt tatccatcag aaacctccta tttcaatcct tcatatccaa ttttttctat
    13081 tttttaaaaa agagaacacc tgcgtgttct ctctttggtt attacttaag ttgcttagca
    13141 acttcttctg caaagttttc ttctctcttt tgtatacctt caccaacttc gaatctcaca
    13201 actttaacaa cttttatatc agaacctact gccttagcaa catcagcaac taattgttta
    13261 acagttatat ctggattttt aacgaaagtt tgctctaata aacaaacctc ttttaattct
    13321 ttttctaatc ttcctttaac cattttttca actatattag ctggttttcc ttcatttaaa
    13381 gcttgttgag ttaatacttc tgtttcatgt gctatgtatt cagcatctac ttcatctctt
    13441 gaaacatact taggattcat agcagcaact tgcatagcta catctttacc taattctaaa
    13501 actttagcat ctctagcttc tgtttccatt tcaacaagaa cacctatttt tccaccaccg
    13561 tgaatgtatc cagcaacttg tccattagtt acaactttag caaatcttct aaagtctaat
    13621 ttctcaccta tttttgcaac tctattattt aaaacttctt gtaaagttat tccttcttta
    13681 tgagtttcac ctaataaaga agctatatct tctttatcag tagctaatgc catacaagca
    13741 gcatctttaa cgaacacttt gaagtcttcg tttttagcaa cgaaatctgt ctctgagtta
    13801 acttctacca tagaagcaac tgtattatca tcattcattt ctattgcaac tagaccttca
    13861 gcagcaactc taccagcttt tttagcagct tttgataatc ctttttctct taataaatct
    13921 actgcttttt ccatgtttcc ttcagcttct tgtaaagctt tcttgcagtc catcattcct
    13981 gcgcctgtac tttctcttaa ctcttttacc atttgagcag ttatattagc cattttttaa
    14041 gtttcctcct acttattcta ttccatatta taaatggtaa gggcgaccct taccatttaa
    14101 ttgtcaaatt attattcttg gtcttcagct acttcttcct cagcaccttg tctaccttca
    14161 attacagctg ttgccatagc accagttatt aattttacgg ctcttatagc gtcatcattt
    14221 cctggtatag caaagtctaa ttgttctggg tcacagttag tatcaactat accaactact
    14281 ggtataccta atctatgagc ttcttgaata gctatgtttt cttttcttgg gtcaactacg
    14341 aacattgcac ctggtaattc aggcatgtct tttattccac ctaagtattt ttctagtttt
    14401 tctttttcag ctcttaattt tataacttct tttttaggaa gaacattaaa tacgccttct
    14461 tcttccattt tttctaattc tcttaattta tttattcttg tttttatagt tttgtggttt
    14521 gttaacattc cacctaacca tctttcatta acaaagtaca ttccacatct ttcagcttca
    14581 tcttttatcg catcttgagc ttgtttttta gttcctacga ataagattgg ctttcctgtt
    14641 tcagctactt ctttagtgaa cttgtaagct tcttcaactt ttttaactgt tttttgtaag
    14701 tcgattatat atattccatt tctctctgtg aatatatact tagccatttt agggttccat
    14761 cttcttgttt ggtgaccaaa gtgaacacct gcttctaata attgtttcat tgatattact
    14821 gacatatctt acctcctggt tttatacctc cagcttgatc ttctccctaa aaaaccatgt
    14881 aataggcacc ttttaaggat cccaatgctg tgtgtgattt attttatttt ttcacctcta
    14941 gtagtatatc acagaggtga agaaataaca atattttttc catattttct atttttatat
    15001 ttttttgtgt attttatacc attttttgaa tttaatttgc aaatttcatt tttaattttg
    15061 tttttaatga tacgttatct atactattat tacttactat atctacactt ccaagtaagt
    15121 cacctgaatt agtataatat tttataatac ccatagtatc acctttttta acagggtact
    15181 ctatattttt aatcttaact tctgacttta tactttcatc atcttttaat attgtataaa
    15241 gttcatcttt tgcttttaat gtaacctcta actctttcgt tccttttata tatttcttac
    15301 caataaagct atctttatca attacttttt tcatattgaa attttctttt ccatatttca
    15361 gtagagctaa tgaagcagag gttcttttat ttttatggtt agtacctaat acaaccccta
    15421 ttactctacg ttttttctca tttttatcat ttttatttac aaccatagaa aatgataagc
    15481 aatatccagc attgccagta tatccagttt ttataccatc tacttctggt ataattctta
    15541 ataatgcatt tgtattgctt ttttcaaaac ttctatctga atttgtatat gtctccatat
    15601 cagttatagc tgttacttgt ttttcataat ggtcaaacat gtattttcca agaatagcta
    15661 tatcttttgc agtagagata ttttcttttg ctggtttttt ggggttgctt aaatcgtata
    15721 ttggaagacc atttggattt agaaaatgtg tattactcat tcctatttct tttgcttttt
    15781 tattcattct atctacaaat gcttctttcg ttttacaaac atgttttgct atagcaattg
    15841 ccgcatcatt tcctgataca atcataagac ctctcataag ctctataagt ggcacttctt
    15901 caccatcttt aagtttataa cttgaccctt ttactgatgc aatagatttg tctattttta
    15961 ccttatcagt ttcttttact tctttatttt caatagcttc tattgcaagt aaaaaagtca
    16021 tcatcttact taaactagct aatggtacct tcatatcagg ttctttacta tataaaactc
    16081 tacctgtttc ttggtctata agtatagatg tttttgaata cttgtctaca gatttatcat
    16141 ctgcatatga ataatttggt attataaaaa ctagaatcat ggctaatgat ataatttttt
    16201 ttagtgcatt tttcaaattt ttcaccttct tggattatta agtatattta tatttaaatt
    16261 ttccctattt agtccaattt atatctagta attaatacct atccatattt acacaaatat
    16321 taccttatca ttcttttaat aatcacagat gcccaaattg ctcctattgt aactccaaaa
    16381 aatacttcta tacctgccaa tgctttccca atcaaacttg tagcaaccat atctccatat
    16441 cctactgtac taaatgtagc catgctaaaa taccataaat ccatatacat tttgaaaatc
    16501 tcacttagtg agtaatcacc tatattattt atatctaaag ctacaagtgt gctatttgaa
    16561 ctttctatgc ctacaaataa gtataataaa gcaaaaacac ttattattgc tataataact
    16621 aataatatat tccatggctt ttctccataa cctgttgtgt aacgtgctat ttggtcaaaa
    16681 aatttttcaa ctaaataatc actgaaggta ggataattag aacgtttcat tattttacta
    16741 ctataaattc tttccttata atagtaaaat cctatcatct catattctcc aatttttgtt
    16801 gcttgatttc tagctattct ataatttatc ttgccatgct catactcact ttttccatat
    16861 tcaacattct ttaacacaaa ttttgtacac atgctaaaaa ttattccatc cattcgtgga
    16921 aaattttcta ctttattaac taccaaatca ggtcctttaa atttcacttt ttcaaatata
    16981 cggtcattta tatagtgttt actaaatatg gttctattaa aatcacagtt ttctaagaat
    17041 acacaaccat taaataaaac tttatctcta aattctgtat agttaaaaat aatattcttt
    17101 ttaaaaatat attttttaaa atttgctttt tgtttaaata tggattcaga aaaatccagt
    17161 attttataat tgtaagttaa tatttcttcc gcattaaatt cattttcaaa aacaaatcca
    17221 ttaaattcac ttatctcttc tttatgaaga gtatccatca tcaattgtat ctcttcatca
    17281 gacttatttt ctttatgaaa gatacaatat ccagaagaat ctgcttctct atgacatttt
    17341 tttctctcat ctattt
//
LOCUS       DAEPKC010000085        17231 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.085, whole genome shotgun sequence.
ACCESSION   DAEPKC010000085 DAEPKC010000000
VERSION     DAEPKC010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17231)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17231)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17231
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.085"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            342..1670
                     /locus_tag="KR294_002833"
     CDS             342..1670
                     /locus_tag="KR294_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBH0240896.1"
                     /translation="MGSNELKKTLGVSAALSTVVGSVIGAGVFFKPQAVYTLTGGAPG
                     LGILAWLIAGIITITAGLTAAEVSVAIPKTGGMMVYIKEIYGEKLGFLTGWMQIVLFY
                     PGMMAALGVIFGEQASALIGSPSLLLPIAIGIIVIVAGLNMLGSKTGGVIQTVSTICK
                     LIPLILIMVVGFIKGGGNNPILTPMVGEGLSLGSVLGQVLIAILFAFDGWMNVGTLAG
                     EMKNPGKDLPKAIIGGLSVVMAVYFIINLAYLWVLPANELANYASPASAVAEVIFGSM
                     GGKIISVGILISVFGALNGFLLTGSRVAYTLATDKTLPKYGIFSKLNSAQVPANAIAL
                     VSVIASIYALSGQFNLLTDLAVFATWIFYVLTFIGVMKLRKTHPNIPREYKVPLYPIV
                     PIIAIASGIFVVVNQLCFAGMKTTMISIGGLVITAIGLPVYAYMTRGVKR"
     gene            2423..3256
                     /locus_tag="KR294_002834"
     CDS             2423..3256
                     /locus_tag="KR294_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase"
                     /protein_id="HBH0240897.1"
                     /translation="MRNKKKKINRKKLYLLLSAIVVCLAFIVVGVRVSSLNMKENEIS
                     RNAKLSSSTITDIVSNTSIEVSKGPSKSSGKIAYITIDDGPSKFTDEMIKTLNKYNVK
                     ATFFMIDGNMKEYPQQVKNIIKNGNTAGFHSVSHDIHKLYVTSTSAKEEFDTNDQTFY
                     KITGKHSKVIRIPYGSKPYTPQASYQALVDAGYKIWDWDLDTEDWRSNSSQIVQNVKN
                     HIKNRKGEDKDQLVVLMHEKKQSAEALDSVLKFLSDEGYEFAPVDQNQIPKNYWLRNL
                     E"
     gene            3349..4281
                     /locus_tag="KR294_002835"
     CDS             3349..4281
                     /locus_tag="KR294_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBH0240898.1"
                     /translation="MVGILSLMMVGCNKSLAKVNDVEITKEQYKKTKAVLSATNNYIN
                     GQSLDELEKTLDKKGRNKLENVIISFMVDNELLYQEAKDKGLTPSKSEVDSKYQELED
                     KMNLNTSYKEKMDKAGVDKDYLKQEISRDLAIDKNKKAFEDRINISDNDMEAYYTSHK
                     KDFNVEEVSASQILISTLDKNKKEVSKDKKEALKKKADNILTKIKNGESFESLAKKYS
                     DDKATGKNGGQLGYFTKDDKNAEFTKEVFKLKKNEVSNVFETSYGYHIVKVTDKRERQ
                     KSFNECQSLIRESILNEKYIEHIKKLNEDAKIDR"
     gene            4333..4815
                     /locus_tag="KR294_002836"
     CDS             4333..4815
                     /locus_tag="KR294_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBH0240899.1"
                     /translation="MFKSLKRTKVEKYIIDNKDSFYRIAYSYTKNEEDALDVVQEAMY
                     KALYSVENIKEVNYIKTWFYKILVRTSIDFIRKNRKYNNMTDIDLIDETGEYDKYTDL
                     DLRRALEELPIEYKSIIILRFFEDLKIEEVAIILDENVNTVKTRLYTALKKLKLKIEE
                     "
     gene            4827..5696
                     /locus_tag="KR294_002837"
     CDS             4827..5696
                     /locus_tag="KR294_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HBH0240900.1"
                     /translation="MTSKERLNKLKDEYHKIPIPKKLDTIINHEKIENIYREKNKKVN
                     RLRFKVAIAFACIFTVLVNISPVFADNFSKIPVIGAIVEVITIKNYSLKSENYEAEID
                     IPKIRGLKDKNLEQRLNSSFMEDGKRLYHQFQERMEKIQSSKNKGYKSLSLSYSVKNN
                     SKKFLSIEMTKNEIEASSYVSKVHYTIDKKRQIVLTLPMLFKDDKYIKVISDNIKEQM
                     REQMKKDSTKSYFIDQKKDLPVEDFKTINKYQDFYFNKNEDLVICFDEYEVAPGYMGA
                     VEFVIPYKVIKDL"
     gene            5739..6494
                     /locus_tag="KR294_002838"
     CDS             5739..6494
                     /locus_tag="KR294_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HBH0240901.1"
                     /translation="MTTYKKLKKSIFKIAIFSICLLVSLVDTNPIFAGSSFNETSNSD
                     TIKVLNAKSINFKQDNYEVNVSIPKIKGLKDKTLENKLNNEFLQDGKKIYSEFQNKMK
                     KENNKGHRYLNVIHNVKNNSKDFLSIEMTKEEIEASSSITKKHYTVDKNRGILLNLPI
                     FFKDSRYIRAISDNIKEQMRNQIKKDDTKSYFIDQDKDSPVKDFESINKYQDFYFNKN
                     GNLVISFDEYEVAPGYMGAVEFVIPNKVIKRLR"
     gene            6536..7357
                     /locus_tag="KR294_002839"
     CDS             6536..7357
                     /locus_tag="KR294_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine dehydrogenase accessory factor"
                     /protein_id="HBH0240902.1"
                     /translation="MNIYEQAIRLIENNEDFAFATITSHSGSTPRETGAMMIVKNDST
                     IFGSVGGGSVEAECIKHAINVIKNRESMLYKFTLNKSDVAKLGMICGGTGEIQIDFID
                     SKLKSNIEKFNKRLKENTSKAYIFGAGHISRDVAVILSLLEFRTVVIDDREEFANHER
                     FPESEVVVLDSFENIPDFPTDENSYIIILTRGHLYDSSALEWALKREAGYIGMIGSRT
                     KIGLTYEKLMKKGFKKEELSKVHAPIGIKLNAQTPAEIAVCIAAELINCRANKEK"
     gene            7362..8123
                     /locus_tag="KR294_002840"
     CDS             7362..8123
                     /locus_tag="KR294_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M48 family metallopeptidase"
                     /protein_id="HBH0240903.1"
                     /translation="MNTGSKDIDTLKVNFRGIEIKAVLVYKNRKNISIKIDPFGKITV
                     MSPPKISKKIIKDIIIEKGDWILKKSEKCKGREEVYKQRMFITGEKFLYLGEEYHLVI
                     KELLRDSVKKSNCRITINEYQIVVQTNDTSTDFIKKSLKSWYKMESERIVLERIDFLK
                     LNCEIMKQLVPASVKVKEQNKRWGSCTAQKNIYINSKISMARLDVIDYVIIHEFSHLA
                     HMNHSKKFYDLVKSIMPDYKDKENWLKINGYKIII"
     misc_binding    8284..8541
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            8654..8893
                     /locus_tag="KR294_002841"
     CDS             8654..8893
                     /locus_tag="KR294_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HBH0240904.1"
                     /translation="MENTVYAKLNQGIDSFLRVAMTLRRREVDIQSISMTVDNMNNSG
                     IKLIVNEEKTSLDSVLNHMKKLHDIREITVERMRH"
     gene            9197..10192
                     /gene="ilvC"
                     /locus_tag="KR294_002842"
     CDS             9197..10192
                     /gene="ilvC"
                     /locus_tag="KR294_002842"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HBH0240905.1"
                     /translation="MKMARMYYEKDVDLEVLKNKKVAVLGYGSQGHAHAQNLRDNGVH
                     VVIGLYDGSKSAQKAKEDGFEVKSVAEATKESDLTMMLMPDEKQKKVYEESVKDNLKE
                     GQTLAFAHGFNIHYNQVQPPEFVDVVMVAPKGPGHLVRNVFTKGSGVPALFAVYQDYT
                     KKATETVLAYAKGIGATRAGVLETTFKEETETDLFGEQSVLCGGISELIKLGYKTLVD
                     AGYQKEVAYFECLHEMKLIVDLIYEGGFERMRYSISDTAEYGDYVSGKRVITDAAKQG
                     MQNVLEDIQNGKFAKAWIKENEEGRENFLKTREEEYNTEIAEVGRNLRSMMSFLK"
     gene            10245..11933
                     /gene="ilvB"
                     /locus_tag="KR294_002843"
     CDS             10245..11933
                     /gene="ilvB"
                     /locus_tag="KR294_002843"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biosynthetic-type acetolactate synthase large
                     subunit"
                     /protein_id="HBH0240906.1"
                     /translation="MSGAKVILECLKKEGIDTIFGYPGGAVIPLYDALYDYSDDFKHI
                     RTSHEQGLVHAADGYARSTNTVGVCFTTSGPGATNAITGIATAFMDSSPMVVISGQVP
                     TSLLGKDSFQEIDITGATLSMTKHNYLVRNTKELVPTIKEAFRVANSGRKGPVLVDVP
                     KDLFLAEMDFSGEDYDLCQIDDYMDYKSDFDLDDETNIKLLNEAIDIIKESKKPIIYA
                     GGGVKSSDSEEILEKFATKIDTPVLNTLMGLGNIDRKNELSLGMVGMHGSRESNLALS
                     NSDLVIAIGARFSDRVISKSSEFAKNAKIIHIDIDPSEISKNIESNVSLVGDVKLVLS
                     LLIERVESKNNSNWKEEIKRFRKSEGVQTYEFHPQNILKKINEKYETLKKPTVVVTDV
                     GQHQMWAAKYWNFKGNKSFITSAGLGTMGFGLGAAIGTKVGNVDKNVVLVTGDGSFRM
                     NCNELATVANYNVPMLILLLNNRTLGMVRQWQKLFSNQRYSQTDINENVDYVKLVNAY
                     NIDGYKVSSMEELGKALDMIDFNKPVFLQCDIDKDYDVYPIVAPNDALENLICN"
     gene            12144..12821
                     /locus_tag="KR294_002844"
     CDS             12144..12821
                     /locus_tag="KR294_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HBH0240907.1"
                     /translation="MFKHDKALLKEVKVERPNPQYAVLMQEQLGGANGELKAAMQYLS
                     QSFRIKDPQIKDLFLDIAAEELSHMEMVAQTINLLNGHDVDYNSVNTGEIETHVLTGL
                     SPVLINSSGAPWTANYVTVTGDLVADLLSNIASEQRAKVVYEYLYRQIDDKYVKETID
                     FLLNREEAHNALFRDALNKVKDTGSNRDFGVTEDSKLYFDLSTPGPNHDTKIDINPPS
                     FEKPLKK"
     gene            12995..15031
                     /locus_tag="KR294_002845"
     CDS             12995..15031
                     /locus_tag="KR294_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin domain-containing protein"
                     /protein_id="HBH0240908.1"
                     /translation="MDSNRKPNNLINEKSPYLLQHAYNPINWYSWNDEAFKKAKEEDK
                     PIFLSVGYSTCHWCHVMEKESFEDEEVAEIMNRNFVAIKVDKEERPDVDSVYMTVCQA
                     MTGSGGWPMTIIMTPDKKPFFAGTYFPKYSRYNRPGVIDLLENVSEKWNTSRDILIKS
                     GDEIIEALKDDFGVKNTEGDLSKEMLSSSVRVFKAIYDEKYGGFGNAPKFPSPQNLMF
                     LMKYYSIEKDKDVLKMVEKTLDGMYRGGLFDHIGFGFSRYSTDKKWLAPHFEKMLYDN
                     AMLTIAFLDAYKITKKELYKEIAIKTIDYVVREMKDKEGGFYSAQDADSEGEEGKFYT
                     FNPLEIIEVLGEEDGIFFNNYFDITSSGNFEGKSIPNLIKNKEYERHNEKIADLSKKV
                     FEYRKERTSLHKDDKILTSWNALMIVALTKAYSTLKNDIYLEYSNKCLNFINNNLVNE
                     SGRLLARYRDGSSDYLAYLDDYAFLIWAYIELYESTFNMKYLEKALNLNESCINLFWD
                     YEKSGFYIYGKDSENLIARPKDLYDGAIPSGNSVQLYNLIRLAKITGDNRLEEMSYKQ
                     LKLYVDNVKSSPTGYSFYMLSLMFELYSTKEIICIFKEDSDLIAFKELISENFIPNAT
                     FLAKKYNEENTIIGFLNNYILKDDKTSYYVCQSNSCSQPINDLQKLKDMILGVE"
     gene            complement(15222..15788)
                     /locus_tag="KR294_002846"
     CDS             complement(15222..15788)
                     /locus_tag="KR294_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBH0240909.1"
                     /translation="MDYSNELKELFLMNQTYATLFTLTNKIQIEGDKYFGILTSRQYM
                     TILSILHLPEEETTLNNIARKMGTSKQNINRLVANLEKNGYVDVIPSPHDKRAINVKV
                     TDLGKKVMVTCSRTGINFMADVFHEFTKDELETLWSLLKKMYRFNGEEQDGFEEDANF
                     MEYEEIDKIKSEALEEFAKRRNRVNKKD"
     gene            16076..17011
                     /locus_tag="KR294_002847"
     CDS             16076..17011
                     /locus_tag="KR294_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBH0240910.1"
                     /translation="MKCTNFTFKGEEGLDIYTYKWEDENIKKPKAVIQIAHGMAETAQ
                     RYETFAKVLTKNGYIVYINDHRGHGKTAKIIENVGHLAEKEGFRCLVEDMYTLTNIIK
                     KENEDLPIYLFGHSMGSFASQRYIMDYSNNLSGLILCGSNGKQGIILNLAHLIINREI
                     KKYGRRSKSNKINNLIFGGEIIRRNEKTKFDWLSRDKEQVEKYINDPFCGVVCSCGFF
                     YDLVQGLKEIEDKENLKKVPLDIPIYIISGDKDPIGKNGKGVLRLRDRYIKLGVKDVT
                     CKLYKDGRHELLNEINREEVFEDIICWLNNKIEIL"
BASE COUNT         6992 a         1709 c         3011 g         5519 t
ORIGIN      
        1 cagaaagaag ccaaaatgtt tttgaaaaaa atgaaatttt attgcaaaaa aatcaaaatg
       61 aatttaactt aatagttata atctattttt agtgttacaa atatacaatg tatattatac
      121 aatataaaaa atacatttac ttagaagtat tattatattt ggatttttgg tttttataat
      181 ttttttatat ttaaacatag ctaaaaataa aagattacga aagctaagta gagtttattt
      241 tattttaata aataataaag ctatttttct atatattggc ataatatatg cttatttaac
      301 tatgaaatta aaattaaata ggattaatga ggaggaaaaa aatgggaagt aatgaactga
      361 aaaagactct tggcgtatca gcagcattat caactgttgt tggttccgtt ataggagcgg
      421 gcgtattttt taaaccacaa gcagtctata cattaactgg aggagctcca ggtcttggta
      481 tattggcatg gttaatagct ggaatcataa ctataacagc tggtcttaca gctgcagagg
      541 tatcagttgc gataccaaaa actggtggaa tgatggtata tataaaagaa atttatggag
      601 aaaaattagg ttttttaact ggatggatgc aaattgtatt attttatcca gggatgatgg
      661 cagcattagg tgttatattt ggagaacaag catcagcact aattggtagt ccatcacttt
      721 tacttccaat agcaattgga attatagtaa tagttgcagg gcttaatatg ttaggttcaa
      781 aaactggagg agtcatacaa actgtttcta caatttgtaa gttaatacca cttattttaa
      841 taatggttgt tggatttatt aaaggtggtg gaaataatcc aatacttaca cctatggttg
      901 gtgaaggatt aagcctgggt agtgtactag gtcaagtttt aattgctata ttatttgctt
      961 ttgatggatg gatgaatgtt ggtactttag ctggagaaat gaagaatcct ggaaaagacc
     1021 ttccaaaagc tataataggt ggattgtcag ttgttatggc tgtttatttt ataataaatt
     1081 tagcgtatct ttgggtatta ccagctaatg aattagcaaa ttatgcttct cctgcatcag
     1141 cagttgctga agttatattt ggttcaatgg gtggaaaaat aatatctgta ggtatattaa
     1201 tttcagtgtt tggagcatta aatggatttt tactaactgg ttcaagggtg gcatatactt
     1261 tagctacaga taagacttta ccaaagtatg gtatattttc taaattaaat tctgctcaag
     1321 ttccagcaaa tgcaatagca ttagtatctg ttattgcatc tatatatgct ttgtcaggtc
     1381 aatttaattt attaactgac ttagctgtat ttgctacttg gatattctat gtattaactt
     1441 ttataggggt tatgaaactt agaaagactc atccaaatat accaagagag tataaagttc
     1501 cattatatcc tattgttcct ataatagcta tagcaagtgg tatatttgtt gtagttaatc
     1561 aattgtgttt tgcaggtatg aaaactacta tgatatctat aggaggtctt gtaataacag
     1621 ctataggctt accagtgtat gcttatatga ctagaggagt aaaaagataa accaagtagt
     1681 ttacaaatgc ttcataatta aaataaaaga gactgtctca aatagagata agtctctttt
     1741 ttattgttaa aatggtaaag atatgtttaa ttttacaaaa aaagagcgtt ccatgaacta
     1801 aaaagtttat tttaaggtat tcattttatt tttagttttt tgattataaa attaaacatc
     1861 taaaaaatta tttattttaa aatactttat tttaaagtgt tttttatcaa actaagtggt
     1921 atctgtacaa caaatattat acatagcttt tatgaaaatt aaatctttct gttatatata
     1981 atagaatatt gtattatata gaaaatatta cctgattaat atagtgattt ataaatgaga
     2041 ttagaaaatt ttatttgata acaaaaatta gataatatga atatataatg tatgtattaa
     2101 aaatgtggca aatagttgtt ttgctattta ttatttgttt aatatttcta atttataaaa
     2161 aaaaaattat aaattttaaa aattataaat gacattttaa ctagaattaa ttgtaaaaaa
     2221 cactatataa tactcaattt tcaacattct atacaattat acagaaatta tacagcataa
     2281 taatcaccga aataacaaat tttaaaaatt aagcaaaact ttttgtcgaa gttcaacgtc
     2341 tatatatatg tagtgtaaat ttttgggata aaatactaca aaaatataaa tgtaaaaata
     2401 tagtaatatt ggaggtcgaa cgatgagaaa taaaaagaaa aaaataaata gaaagaagtt
     2461 gtatttgctt ttaagtgcta ttgtagtgtg tctggctttt atagtagttg gtgttcgcgt
     2521 cagctcttta aatatgaagg aaaatgaaat tagtagaaat gcaaaactgt caagttctac
     2581 tattacagat atagtatcta atacatcaat agaagttagt aaagggccaa gtaaaagttc
     2641 tggaaaaata gcatacataa ctatagatga tggtccatct aaatttactg acgagatgat
     2701 aaaaacttta aataaataca atgttaaagc aacttttttt atgatagatg ggaatatgaa
     2761 ggaatatcca cagcaagtta aaaatataat taaaaatggg aacacagcag gttttcatag
     2821 tgtatcacat gatattcaca agctttatgt tactagtaca tcagcaaaag aggaatttga
     2881 tacaaatgat caaacttttt ataagataac tggtaaacat tcaaaagtaa taagaatacc
     2941 ttatggaagc aaaccatata caccacaagc ctcttatcag gctttagttg atgctggata
     3001 taaaatttgg gactgggact tagatacaga agactggaga tctaattctt ctcaaattgt
     3061 acaaaatgta aaaaatcata ttaagaatag aaaaggtgaa gataaagacc aacttgtagt
     3121 tttaatgcat gagaaaaaac agagtgcaga agctttagat tcagttttaa aattcttatc
     3181 agatgaaggt tatgaatttg cgccagtaga tcaaaaccaa ataccaaaaa attattggtt
     3241 acgtaattta gagtagttaa aatataagaa tattgattga tatttttaga aattgagaat
     3301 aaaaatgagt gaggtgtagg tatattgaat aaaaaacttt atataggaat ggtcggaata
     3361 ttgtctttga tgatggttgg ttgtaataaa agtttagcaa aagtaaatga tgtggaaatc
     3421 acaaaagaac agtacaaaaa aacaaaagca gttttatctg ctactaataa ttatataaat
     3481 gggcagtctt tagatgaatt agaaaaaact ttggataaaa aaggtagaaa taaattagaa
     3541 aatgttataa tatcgtttat ggtggataat gaacttttat atcaagaggc taaggataaa
     3601 ggactaactc caagtaaaag tgaagtagac tcaaaatatc aagaactaga agataagatg
     3661 aatttgaata caagctataa ggaaaaaatg gacaaagcag gtgttgataa agattattta
     3721 aaacaagaaa tatctagaga tttagcaata gataaaaata aaaaggcctt tgaagataga
     3781 ataaacataa gtgataatga tatggaagcc tactatacaa gtcataaaaa agattttaat
     3841 gtagaagaag taagtgcttc tcagatactt atatcgactt tagataaaaa taaaaaagaa
     3901 gtaagcaaag ataaaaaaga agctttgaag aagaaggcag ataatatatt gactaaaatc
     3961 aaaaatggag aaagttttga aagtttggct aaaaaatatt cggatgataa agcaactgga
     4021 aaaaatggag gacagctagg atattttaca aaggatgata aaaatgctga gtttacaaag
     4081 gaagtgttca aattaaagaa aaatgaagtt tcaaatgtgt ttgaaactag ttatggatat
     4141 catatagtca aagttactga taaaagagaa agacaaaaaa gttttaatga gtgtcagagt
     4201 ttaataagag aatctatttt aaatgaaaag tatattgagc atataaaaaa actgaatgaa
     4261 gatgctaaaa tagacagata gaatttctaa cagctcaatc ctagcctgta atcggaggga
     4321 gattttacag gaatgtttaa gagtttaaag agaacgaaag ttgagaaata cattatcgat
     4381 aataaagact ctttttatag aatagcatat agttatacga agaatgaaga agatgcctta
     4441 gatgtggttc aagaagccat gtataaggca ctatactcag tggaaaatat taaagaagta
     4501 aattatataa agacatggtt ttataaaatt ttagttagaa cgagtataga ttttattaga
     4561 aaaaaccgta aatataataa tatgacagat attgacctta tagatgagac tggagagtat
     4621 gataaatata ctgatttgga tttaagaaga gctttggaag aattacctat tgaatacaaa
     4681 tctattataa tattaagatt ttttgaagat ttaaagattg aagaagtagc aataatattg
     4741 gatgaaaatg tgaatactgt taaaactagg ttatatactg ctttaaaaaa actaaaatta
     4801 aaaattgaag agtagggata aaaagaatga caagcaaaga aaggttaaat aagttaaaag
     4861 atgagtatca taaaattcca atacccaaga aattagatac tataataaat catgaaaaaa
     4921 tagaaaacat atatcgagag aaaaataaaa aagtaaatag attaagattt aaagttgcaa
     4981 tagcctttgc atgtatattt acagtattag taaatataag tcctgtattt gcagacaatt
     5041 tttctaagat acctgtaatt ggagcaatag tagaagtaat aactataaaa aattatagtt
     5101 taaaaagtga aaattatgaa gctgagattg atattcctaa aatacgaggt ttaaaagata
     5161 aaaacttaga acaaagatta aacagtagtt ttatggaaga tggaaaaagg ctttatcatc
     5221 aattccaaga gagaatggag aagatacaat catcaaagaa taaaggatat aaatctttaa
     5281 gtttgagtta tagtgtaaaa aataattcta aaaaatttct atcaatagag atgacaaaaa
     5341 atgagataga ggcttcatca tatgtgagta aggtacatta tactattgat aaaaaaagac
     5401 aaatagtttt gactttgcca atgcttttta aagatgataa gtatataaaa gttataagtg
     5461 ataatataaa agaacaaatg agagaacaaa tgaaaaagga tagtacaaaa tcctatttta
     5521 tagatcaaaa aaaagacttg cctgttgaag attttaaaac aattaataag tatcaggatt
     5581 tttattttaa taaaaatgaa gaccttgtaa tttgttttga tgaatatgaa gtagcacctg
     5641 gttatatggg cgcagttgag tttgtaatac catataaagt aataaaagat ttgtaaattg
     5701 aatagtagtt tatatataaa tcttttaagg aggacaatat gactacatat aaaaaactta
     5761 aaaaatctat atttaaaatt gctatatttt caatatgctt attagtttca ttagtagata
     5821 caaaccctat atttgcaggt agttccttta atgaaacttc aaatagtgat acgataaagg
     5881 tgttaaatgc taagagtatc aactttaaac aagacaatta tgaagtgaat gtgagtattc
     5941 ctaaaataaa aggtttaaaa gataaaactt tagagaataa attaaacaat gagtttttgc
     6001 aagatgggaa aaaaatttac agtgaatttc aaaataaaat gaaaaaggaa aataataagg
     6061 gtcatagata cctaaatgta atccataatg tcaaaaataa ttctaaggac tttttatcaa
     6121 tagaaatgac aaaagaagag atagaagctt cctcatctat aactaagaag cattacactg
     6181 ttgataaaaa tagaggaata ctattaaatt taccaatatt ttttaaagat agtagatata
     6241 ttagagctat aagtgataat ataaaagagc agatgagaaa tcaaattaag aaagatgata
     6301 caaaatctta ttttatagac caagataaag actcgccagt gaaagatttt gaatctataa
     6361 ataagtatca agatttttat tttaataaaa atggaaatct tgtgattagt tttgatgaat
     6421 atgaagtagc tcctggttat atgggagcag tagaatttgt gataccaaat aaagtaataa
     6481 aaagactaag atagatatat agaagatttt tagatagact ggtaaggaga attatatgaa
     6541 tatatatgaa caagcaataa gattaataga aaataatgag gatttcgcat ttgctacaat
     6601 aacgtctcat tcaggttcaa caccacgtga aactggagca atgatgattg tgaaaaatga
     6661 ttctactata tttggctcag taggaggagg tagtgtagaa gcagaatgta taaaacatgc
     6721 aattaatgtt ataaaaaaca gagaatcaat gttgtataaa tttactctaa acaaatctga
     6781 tgtggcaaaa ctaggaatga tatgtggagg tactggagaa atacaaatag attttataga
     6841 tagtaaatta aaaagtaata tagaaaaatt taataagaga ctaaaggaaa atacaagtaa
     6901 agcatatata tttggtgcag gtcatatttc aagagatgtt gctgtgatac tatctctttt
     6961 agaatttaga acagtagtaa tagatgatag agaagaattt gctaatcatg aaaggtttcc
     7021 agaatcagaa gtagtagttt tagattcttt tgaaaacata ccagattttc ccactgacga
     7081 aaatagttat ataattattt taacaagagg tcatctatat gattcaagtg ctttagaatg
     7141 ggctcttaaa agagaggctg gttatatagg tatgattgga agtagaacaa aaattggatt
     7201 gacttatgaa aaactcatga aaaaaggttt taagaaggaa gaattatcaa aagtacatgc
     7261 accaataggc ataaaattga atgctcaaac accagctgaa atagctgtat gtatagctgc
     7321 tgaacttata aattgtagag ctaataagga aaaataaact aatgaacaca gggagtaaag
     7381 atattgatac tttaaaggtt aattttagag ggattgaaat aaaagcagtt ttagtatata
     7441 aaaatagaaa aaatatttct ataaaaatag atccatttgg caaaataact gtaatgagtc
     7501 ctcctaaaat atccaaaaaa ataataaaag atataattat tgaaaaagga gactggatac
     7561 ttaaaaagtc agaaaaatgt aaaggaagag aggaagtata taaacaaaga atgtttataa
     7621 ctggcgaaaa atttctttat ttaggtgaag agtaccatct agttataaaa gaactgttga
     7681 gagattctgt caaaaaaagt aactgtagaa taactattaa cgaatatcaa atagttgttc
     7741 agacaaatga tacaagtaca gattttatta aaaaatcttt aaaatcttgg tataagatgg
     7801 aaagtgaaag aatagtatta gagagaatag attttcttaa attaaattgt gaaataatga
     7861 agcaattagt tccagcgagt gttaaggtaa aagaacaaaa taagagatgg ggaagttgta
     7921 cagctcaaaa aaatatttat ataaactcaa aaatatctat ggcaagatta gatgtaattg
     7981 attatgtaat aatacatgag tttagccatt tagcacatat gaatcactct aaaaaattct
     8041 atgatttagt aaaatccatt atgcccgatt ataaagataa agaaaattgg ctaaaaataa
     8101 atggatataa aataataatc tgaaaacgat tattccaaaa tataggcgta aagtataaaa
     8161 gaagtattat tgtgaaaaaa ataaataatc tgaaaatttt aaaaaaagtc attgacattg
     8221 taaatgatag agaatataat ctatattaac aacaaaacag aattgaaata taaaattaaa
     8281 aaattaaaag caatgacaga gacaacaata ctaatagtgt tatccacaga gaaccaatgt
     8341 tgctgagaat tggtgttaac agtagtataa tgatcactct ggagcttttg tactgaatat
     8401 ttttagtaag tacaaacgta tgtcaacgtt acatgactaa ggttaaggta attaattacc
     8461 cgacctgaaa aaagaggggt agatgtattt tttatatcta caaataaggt ggtaccgcgg
     8521 aatataactt tcgtccttat aagtaatatt tatattgctt ataaagatga aagttttttt
     8581 attttaagtg atataaataa atttaatcca tataaaatta ataaaaaaat aataaaaata
     8641 aggagggatt tttatggaaa atactgtata tgctaaatta aaccaaggaa tagattcttt
     8701 tttaagagtg gctatgactc taagaagaag agaggttgat atacaatcaa taagtatgac
     8761 tgtagataat atgaataatt caggtataaa attaatagta aatgaagaaa agacatcctt
     8821 agattctgtc ttaaaccata tgaaaaaact acatgatata agagagataa ctgttgaaag
     8881 aatgagacat taattaaata tattttataa aactaaagat aaatatgctt attttaaaat
     8941 aaaaaactaa agataaatat taaataagaa aaatcttaga ttaaaatata agtgtcattg
     9001 aatttattag tttatcacag ttaataaatt tattagtttg ttgtagctaa taaaaactga
     9061 aaattctaaa attataattg taagattata taaatttaga atttaaatct gttgaataat
     9121 attaaaacaa tgataatgag tatgaatttc taataaaaat aaatatcata aaaataagaa
     9181 aaagtattgg gaggaaatga aaatggcaag aatgtattat gaaaaagatg tggatttaga
     9241 ggttttaaaa aataaaaagg ttgcagtttt aggttatgga agtcaaggac atgcacatgc
     9301 acaaaatctt agagataacg gtgtacatgt agtgataggt ctttatgacg gaagtaaatc
     9361 agcacaaaaa gcaaaagaag atggatttga agttaagagt gtagcagaag ctacaaaaga
     9421 aagtgatttg acaatgatgt taatgcctga tgaaaagcaa aagaaagttt atgaagagag
     9481 tgtaaaggat aacttaaaag aaggtcagac attagctttt gctcatggat tcaatataca
     9541 ttataatcaa gtacaaccac cagaatttgt tgatgttgta atggtagctc ctaaaggacc
     9601 tggtcactta gttagaaatg tatttacaaa gggaagtgga gttcctgcac tatttgcagt
     9661 atatcaagac tacactaaaa aagctacaga gacagtttta gcatatgcaa aagggatagg
     9721 agcaacaaga gcaggtgttt tagaaactac ttttaaagaa gaaacagaaa cagatttatt
     9781 tggagaacaa tcagtacttt gtggtggaat aagtgaactt ataaaattgg gatataaaac
     9841 gcttgtagat gcaggttatc aaaaagaagt agcatatttt gaatgtttac atgaaatgaa
     9901 actaatagtc gaccttatat atgaaggtgg atttgaaaga atgagatata gcataagtga
     9961 cacagcagaa tatggagatt atgtatctgg taaaagggta ataactgatg ctgcaaaaca
    10021 aggtatgcaa aatgttttag aggatataca aaatggaaaa tttgcaaaag cgtggattaa
    10081 agaaaatgaa gaaggacgtg aaaacttcct aaaaactaga gaagaagaat ataatacaga
    10141 aattgccgaa gttggtagaa atctaagaag tatgatgtca ttcttaaaat aaatatatat
    10201 taaatggatt agtttgaggg aaagagtggt gtatagtagt gcgtatgagt ggagcaaagg
    10261 taattttaga atgtttaaag aaagagggaa ttgacacaat atttggatat cctggtggag
    10321 ccgtgatacc tctttatgat gctctatacg attattcaga tgattttaaa catataagga
    10381 catcccatga acaaggttta gttcatgctg cagatgggta cgcaagaagt actaatacag
    10441 taggagtttg ttttacaaca tctggtccag gagcaacaaa tgccataact ggaatagcaa
    10501 cagcttttat ggattcttca cctatggttg taatttcagg gcaggtgcca actagtttat
    10561 taggaaaaga ttcttttcaa gaaattgaca taactggagc aacattatct atgacaaaac
    10621 ataattattt agttagaaac actaaagaat tagttcctac aataaaagaa gcttttagag
    10681 ttgcaaattc aggtagaaaa ggacctgtac ttgtagatgt tccaaaagat ttatttttag
    10741 cagaaatgga ttttagtggt gaggactatg atttatgtca aatagatgat tatatggatt
    10801 ataagagtga ttttgatcta gatgatgaaa ctaatattaa gcttttaaat gaagcaatag
    10861 atatcataaa agaatctaaa aagcctataa tatatgcagg tggaggtgtt aaatcttcag
    10921 acagtgagga aattcttgaa aaatttgcaa ctaagataga tacacccgta ctaaatacac
    10981 ttatggggct tggaaatata gatagaaaga atgaattatc tcttggaatg gttggaatgc
    11041 atggaagtag agaaagtaat ttagcacttt ctaattcaga tttagtaata gcgataggtg
    11101 cgagatttag tgatagagtg ataagtaaaa gttctgaatt tgctaaaaat gcaaaaataa
    11161 tacacataga catagaccca tctgaaataa gtaaaaatat agaatctaat gtatctttgg
    11221 ttggagatgt aaagctagtc cttagtttat taattgaaag ggttgaaagt aagaataata
    11281 gcaattggaa agaagagata aagagattta gaaagagtga gggtgtacaa acatatgaat
    11341 ttcatccaca aaatatacta aaaaaaataa atgaaaaata tgaaacatta aagaaaccca
    11401 ctgtggtagt aactgatgtc ggtcaacatc aaatgtgggc tgctaagtac tggaatttta
    11461 aaggtaataa aagttttata acatcagcag ggttaggaac tatgggattt ggtttaggtg
    11521 cagctattgg aactaaagtt ggtaatgtag ataaaaatgt agttttagtc actggtgatg
    11581 gaagttttag aatgaactgt aatgaactag ctacagttgc aaattataat gtacctatgc
    11641 ttattttatt actcaataat agaacattag gaatggtaag gcaatggcaa aagttatttt
    11701 ccaatcaaag atactctcaa actgacatta atgaaaatgt ggattatgtt aaactcgtaa
    11761 atgcatataa tattgatgga tataaggtat ccagtatgga agaattagga aaggcgctag
    11821 atatgataga ttttaataaa cctgtatttt tgcaatgtga tatagataag gattatgatg
    11881 tttatcctat tgtagcacct aatgatgcat tggaaaattt gatatgtaac taaaacttat
    11941 actgaatatt gataaaattt tttattaaat ttttattggt attcagtttt tgttgtttag
    12001 agatagattg gcatttttta tttttgcaaa taaatcaatg actatataat taagaactta
    12061 ttaaatttta attatacaat ttagaatagt attacaactt aagtaaataa taattttgaa
    12121 taataattta cggaggtatt catatgttta aacacgataa agcattatta aaagaagtaa
    12181 aagtagaaag accaaatcct caatatgctg ttttaatgca agaacagttg ggtggtgcaa
    12241 atggagagtt aaaagcagct atgcaatact tgtcccaaag ttttagaata aaagaccctc
    12301 aaataaaaga tttatttctt gatatagcag cagaagagct tagccatatg gaaatggtag
    12361 cacaaactat aaatttatta aatggacatg atgttgatta taattcagtt aatacaggcg
    12421 aaatagaaac acatgtatta actggtctat caccagtctt aataaactca tcaggagctc
    12481 cttggactgc taattacgtt acagttacag gggatttagt agctgactta ctttcaaata
    12541 tagcttctga acaaagagct aaggtagttt atgagtactt gtatagacaa atagatgata
    12601 aatatgtaaa agaaacaata gatttcttac ttaatagaga agaagcacat aatgctctat
    12661 ttagagatgc tttaaataaa gttaaagata caggttcaaa tagagatttt ggagttacag
    12721 aagattctaa attatatttc gatttgtcta ctccagggcc aaatcacgat actaagatag
    12781 atattaatcc tccttctttt gaaaaacctt taaaaaaata atttgatatt ttttatgttg
    12841 ttttgtttta gtagttataa aaattattta ctaggagaat taattatatg aaaaattaaa
    12901 tatgtatggt taaaaatggg tatacactta ttataagtgt atatctattt gtttattgca
    12961 aaacatataa taaaataaca aatgaggtgg tattttggac agtaatagaa aacctaataa
    13021 tctaataaat gaaaaatctc catatctttt acagcatgca tataatccta taaactggta
    13081 tagttggaat gatgaggctt ttaaaaaagc aaaagaagag gataagccaa tatttttaag
    13141 tgtaggatat tcaacatgtc attggtgcca tgttatggaa aaagaatctt ttgaagatga
    13201 agaagttgct gaaataatga atagaaactt tgtggcgata aaagtagata aagaggaaag
    13261 acctgatgta gatagcgtgt atatgacagt ttgccaagcc atgacaggta gtggtggatg
    13321 gccaatgacc ataataatga caccagataa aaaacctttt tttgcgggaa catatttccc
    13381 aaaatattca aggtataata gacctggagt tatagattta ttagagaatg tatctgaaaa
    13441 gtggaataca agcagggata tattaataaa atctggagat gaaataatag aagctcttaa
    13501 ggatgatttt ggtgtaaaaa atactgaggg tgatttatca aaagagatgt tgagttcatc
    13561 agttagagta tttaaggcta tttatgatga aaagtatggt ggttttggta atgctcctaa
    13621 atttccaagt cctcagaatc ttatgttttt aatgaaatat tatagtatag aaaaagacaa
    13681 agatgtgtta aaaatggtgg aaaaaacttt agatggaatg tatagaggag gcttgtttga
    13741 tcatattgga tttgggtttt caagatactc tactgataaa aagtggttgg ctcctcattt
    13801 tgaaaaaatg ctatatgata atgctatgct tactatagct tttttagatg cgtataaaat
    13861 aacaaagaaa gagttatata aagaaattgc tataaaaact atagattatg tagttagaga
    13921 gatgaaggat aaagaaggtg ggttttattc agcacaggat gctgatagtg aaggtgaaga
    13981 aggtaaattt tatacattta atcctcttga gataattgaa gttttgggtg aagaagatgg
    14041 aattttcttt aataattatt ttgatataac tagtagtgga aattttgaag gcaaaagtat
    14101 tcctaatctt ataaaaaata aagaatatga gagacataat gaaaagatag ctgaccttag
    14161 taaaaaggta tttgaatata gaaaagaaag aacatctttg cataaagatg acaagatact
    14221 tacatcatgg aatgcattga tgatagttgc tttaacaaag gcatatagta ctttaaaaaa
    14281 tgacatatat ttagagtatt caaataagtg tcttaacttt ataaataata atcttgtaaa
    14341 tgagtcaggt agattattag ctagatatag agatggaagt tccgactatt tagcatattt
    14401 agatgattat gcttttttaa tctgggcgta tatagagctt tatgagtcaa catttaatat
    14461 gaaatattta gaaaaggctt taaatttgaa tgaaagctgt atcaaccttt tttgggatta
    14521 tgaaaaaagt ggattttata tatatggtaa agatagtgaa aatttaatag caagaccaaa
    14581 agatttgtat gatggagcta ttccatcagg aaattctgtt caattataca atcttataag
    14641 acttgcgaaa attactggag ataatagact tgaagaaatg tcatataaac aattaaaact
    14701 gtatgtggat aatgtaaaga gttctccaac tggctacagc ttttatatgc tttcattgat
    14761 gtttgaactt tattctacta aggaaattat atgtattttt aaggaagatt ctgatttaat
    14821 tgcatttaaa gaattgataa gtgaaaattt tataccaaat gcaacttttt tagcaaagaa
    14881 atacaatgaa gaaaacacta ttataggttt tttaaataac tatatattga aggatgataa
    14941 gactagttat tacgtgtgtc aaagtaatag ttgtagtcaa ccaattaatg atttacaaaa
    15001 attaaaagat atgattttag gagtagaata atcataatag cgaaaaagga gatgctttaa
    15061 aataaaagtc taatcatctc ctttttttgt ataaaaaaca gaaaaagagt tcctaagaac
    15121 acctaatcta tgtaatgatt gttttgttaa aaaataaaaa tgacattata gttatataaa
    15181 atattgtact ataaaaaagt ggtattatag atgcgatagt attaatcttt tttatttacc
    15241 ctatttcttc tttttgcaaa ttcttcaagt gcttcagatt taattttatc tatttcttca
    15301 tattccataa aattagcatc ttcttcaaag ccatcttgtt cttcaccatt aaaacgatac
    15361 atttttttta gtaaactcca taaggtctct aattcatctt tggtaaattc gtgaaataca
    15421 tctgccataa agtttattcc agtcctacta catgttacca taaccttttt tcctaagtct
    15481 gtaactttaa cattaattgc tctcttatca tgaggacttg gaattacatc aacatatcca
    15541 tttttttcaa gattagcaac tagtctattt atattttgtt tacttgtacc catttttctt
    15601 gcaatattat ttaatgttgt ttcttcctct ggtaaatgaa gaattgataa aatagtcata
    15661 tactgtcttg aagtaagtat accaaaatat ttatctcctt ctatttgtat tttgtttgta
    15721 agggtaaaaa gagttgcata tgtttgattc attaaaaaga gctcttttag ttcatttgaa
    15781 taatccatga aatatatctc ctttattttt agatgttgtt ttgtcgaaaa cagaatatca
    15841 tgaattaatt ctaatgtcaa tatggtgtca aaatatatta aagtattact tttttatgta
    15901 actattaatt aattaaatta ttgtataatt ttatgtaaaa acttctatgt accaatgata
    15961 atttctatga ggaattaata attcttaaat tttttagaaa gattttgact tgaaaatact
    16021 tgtaatataa tatataaatt aatatactga ataaaatcaa tctggaggga taattatgaa
    16081 gtgtacaaac tttactttca aaggagagga aggtttagat atatatacat ataaatggga
    16141 agatgaaaat ataaaaaaac caaaggcagt tatccaaatt gcacatggaa tggctgaaac
    16201 tgcacaaagg tatgagactt ttgccaaggt acttactaaa aatggttata tagtatatat
    16261 caatgaccat agaggtcatg gaaaaactgc aaagataata gaaaatgttg gacatttagc
    16321 tgaaaaagaa ggatttagat gtcttgtaga ggacatgtat actttaacaa atattataaa
    16381 gaaagaaaat gaagatttgc caatttatct atttggacac agcatgggtt catttgcaag
    16441 tcaaagatat ataatggatt acagtaataa tttatctggt cttatactat gtggttcaaa
    16501 tggaaagcaa ggaatcattc taaatcttgc tcatctgata atcaatcgtg agattaaaaa
    16561 gtatggaaga cgttctaaaa gtaataaaat aaataatttg atatttggtg gcgaaataat
    16621 aagaagaaat gaaaagacta agtttgactg gttaagtaga gataaagaac aagttgaaaa
    16681 atatataaat gacccatttt gtggagtagt gtgtagttgt ggcttttttt atgatttagt
    16741 tcaagggtta aaagaaattg aggataaaga aaacttaaaa aaagtgccac ttgatatacc
    16801 tatttacata atatctggag ataaagaccc cataggaaaa aatggtaaag gagtcttaag
    16861 actaagggat agatatataa aattaggagt aaaagatgta acttgcaaac tttacaaaga
    16921 tggaaggcat gaattgttga atgaaataaa tagagaagaa gtttttgagg atataatttg
    16981 ttggttaaat aataaaatag aaatattgta ataaaaaaat ataatgatat atttgcttta
    17041 aatttattta tatataatat ttgaaaagtg gattatgtat atgcaaagta gaaaagagag
    17101 agcctagaag tgattttttg ctataatgcc atttattgaa taggtgggtg ttattataaa
    17161 taaattatta acactcagta tgattatcat tgtatatgga atttatttta tttaaaattc
    17221 cttgaaagtt t
//
LOCUS       DAEPKC010000086        16854 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.086, whole genome shotgun sequence.
ACCESSION   DAEPKC010000086 DAEPKC010000000
VERSION     DAEPKC010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16854)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16854)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16854
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.086"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(<1..273)
                     /locus_tag="KR294_002848"
     CDS             complement(<1..273)
                     /locus_tag="KR294_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBH0240911.1"
                     /translation="MNFKKFSFSSIYLIIAVGIIFTAILFSISIYLITGDLKLIALLL
                     IYTMVLCGFIALIIFLLHKKIVIFCSKICHTLDSMMNSEDNIEIELE"
     gene            complement(263..949)
                     /locus_tag="KR294_002849"
     CDS             complement(263..949)
                     /locus_tag="KR294_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0240912.1"
                     /translation="MEKILVVEDDSILNKTLSYNLIEDGYIITSKFTAKSALKSIFEC
                     EFDLIILDINLPDKSGFELCNEIKENYNIPIIFLTANDMECDMIKGYELGALDYITKP
                     FNINIFKQKIKAFLNHLTIKTKQDYYKDGYLEINFSELSANINGNQIIFTPLEYRTLK
                     LLTENPKSILTRKVLLEKLWDIDANFVDEHTLTSVISRIRSKIEKDNLKYIKTVYGMG
                     YMWLGERNEF"
     gene            complement(1107..2171)
                     /locus_tag="KR294_002850"
     CDS             complement(1107..2171)
                     /locus_tag="KR294_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S ferredoxin"
                     /protein_id="HBH0240913.1"
                     /translation="MKRVDERNTMFARANYKKDSTAYNDYYKKNPDKKEIDDSIRNRP
                     NLCSEGTMTYNELNSPMASSAFDFLSDIKSLCEGKVSDTKVDVDAKSMTKKIKGLAKQ
                     YGASVVGITKLKDYHIYTNRGRHEENYGEEINLTHKYAIVFGCEMDKEMINRAPMICE
                     VIETSKCYVDASIVGMILSYYIRNLGYDARNHMDANYLVMPVFIARDAGLGDIGRNAI
                     LTNKDYGSRLRLGVVTTDIPLLEDEYVDFGLEDFCKVCKKCSFNCPSHSLSNDIKIGD
                     DGKYNWVIEHETCYIKWRYLGTDCGMCISACPFSQNLETIKNTTSFKGNNELIQKALD
                     EYTSKFGKRIFIPGNPSWLK"
     gene            2433..3104
                     /locus_tag="KR294_002851"
     CDS             2433..3104
                     /locus_tag="KR294_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0240914.1"
                     /translation="MNLLIIEDDINLNEGLFYAFENDGFNVFKAYTKQEGLNIFNSKN
                     IDFIILDCNLPDGDGFDVCQIIREKSDIPIIMLTARDSEIDEVKGLEIGLDDYITKPF
                     SLSVLKARVKVAIRKKSNNKVIYSNGIKLDQKLLKVYKNKECLELSSVEYKLLSYLIE
                     NKGQILLKEQILHHIWDSEENYVDDNIVSVNIRRLRVKVEDDPSNPKYIKTAYGMGYL
                     WNEVE"
     gene            3106..4014
                     /locus_tag="KR294_002852"
     CDS             3106..4014
                     /locus_tag="KR294_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH0240915.1"
                     /translation="MFILAFIICTVVIFIVSTKINRKRYDELNLMLNQILEGKEVTYP
                     DTKDTRASKISHQVKKIKDMIEIEVEQSKSEKEAIKGLISNMSHQLKTPLSNITIYCE
                     LLENINISTLQKKEFLQKMKNETFKIDWLLQSLFKMTKLEDGVIEFEVEELLIKDTLI
                     QSISTIFNKAEAKNIRINLEPFSDIKLVHNKKWTIEAIVNVLENAIKYSPSDSTITIS
                     VIKMELYTKITIKDEGIGIDSRELNDIFKRFYRSKNVENQNGTGIGLYLTRLILEKEN
                     GNIIVESKLGSGCCFSIFLQNCKSLN"
     gene            4091..4777
                     /locus_tag="KR294_002853"
     CDS             4091..4777
                     /locus_tag="KR294_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0240916.1"
                     /translation="MSILVTNNLVKHYGKGETKVKALNGVSIEIERDTFTAIVGTSGS
                     GKSTLLNIIGGLDNPTSGDVIIKGKNISKIGKKDLTVFRRRNIGFIFQNYSLMPVLNT
                     YDNIALPVTLDKGNHIDHEYIEMLMKTLGIWDKRLKFPSELSGGQQQRVAIARALANK
                     PALILADEPTGNLDSKTTMEVVCLLKESSAKFHQTILMVTHNENIAQVCDSIIHIEDG
                     VVVNTGGELL"
     gene            4774..7329
                     /locus_tag="KR294_002854"
     CDS             4774..7329
                     /locus_tag="KR294_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HBH0240917.1"
                     /translation="MMSLVKFSIQYIKHYKKQSISIVLSIVLSVALLTGIGSLVHSAD
                     KSRIEKIREDSGDYHYFYKVDKEQLNKIKENKKSKEYTVDRLGVTKPKNQIDEPFIIE
                     FLNADSSYLDMTGRKLLKGTLPSKDGEIVLDTYSLNNLNVNKEIGTEINLDGKIYKLC
                     GILSSLSNPETALEGFVNDYFQPKEKDSYIVYVKYDENKNIKKQNYKFMKKFNISKEK
                     TYINWSLSVEFGVKPPKNIEKYNIFEFLKNLELNTNAIILLVGVFGAAAVYSIFHVSI
                     LQRISQYGVLEVLGANNKQLLFLLFLELFLLFIVGFPIGCFLGIGVASTIYEQFPHIF
                     LSSDIVPGAFFISEKSIYLGFLFILLLLILIAVRVVHQLNKYSSIESMKNFKITNKKK
                     RILESVKHSNMTKVLSHKYMTQKKGMFIGILFSLSLGGIIFLCSSYSIQLTKNNNELT
                     MKADDGLNSDYQITMQTTDFDVGIPKDKISRLNNVEGISKVYPVRYLFGAMQIKEEQL
                     FWKNFFKPLEKDYRIKTFFDGICTKQNEGGYLLKTNIYGYNNGMLEGLNSYIIDGEIN
                     THDMVKNNKVIVRLPMDGTGMYDAVDINPGDTIKVKVPKTMKPTDEIVKFKEENKNDY
                     TTKEFVVAATVKRVMANNIYFIGDYGMDIVMTNGQMKNNFDIENYNSVSIKKTEDSNS
                     EELSENIKSVVSDVKRCIVTDYTIAIEKNNTYLNQKLLFIYGIVFVLLAISLFHIINT
                     VSYLIFSRRHEFGILRAMGITDNKFLLMMIREGFLYGFYASIIMVIGSVIGQFMIYFM
                     VKRVYLYINPILKINTPLYIGMIILNITISIVAVIIPVRQILKSDIISEINKN"
     gene            complement(7523..8722)
                     /locus_tag="KR294_002855"
     CDS             complement(7523..8722)
                     /locus_tag="KR294_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003493023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coenzyme F420-0:L-glutamate ligase"
                     /protein_id="HBH0240918.1"
                     /translation="MDRLVGTVSRGVRAPIIRQGDDLVKIVVDSVLNASKSENFEVRD
                     KDVIAVTEAVVARAQGNYAHVDNIAKDVKDKFGDDTVGVIFPILSRNRFAICLKGIAK
                     GCRKVVLMLSYPSDEVGNHLISIDELDDKGINPWSDVLTEEKYRELFGYNKHTFTGVD
                     YVDYYKNLIKDCGAEVEIVFANNPKTILNYTTSILTCDIHTRQRTKRILRQNGAKKVY
                     SLDDIMTASVDGSGYNDQYGLLGSNKATEETVKLFPINCDEVVNKIQGNIKEITGKDV
                     EVMVYGDGAFKDPVGKIWELADPVVSPAYTKGLEGTPNEVKLKYLADNDFADLSGDEL
                     KEAISKYIVEKDNKSDDLTGNMVSQGTTPRRLTDLIGSLADLTSGSGDKGTPIIYIQG
                     YFDNYTK"
     gene            8841..9728
                     /locus_tag="KR294_002856"
     CDS             8841..9728
                     /locus_tag="KR294_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBH0240919.1"
                     /translation="MNIKLELYKVFNAVVNNKSFSLAAKELFMSQPAVSQSIKQLEEQ
                     LDTLLFYRNNKGVKLTPEGKILSEHVTTALKLISSGEDRINKFKKLEYGSLKIGVGDT
                     AARFFLLKYLEIFHKKYPHIHVSTINRTSRELISLLKDGNIDIAIINMPIEDDTLNIV
                     ECIEIHDIFVCANDYIEYKGRKISLEELNTLPLIMLENKANSRLYVNEYFLSKGIKLN
                     PDIELGSHELLLEFAYINLGVSCVIEEFSIDYLENEKLFKLDIKEPIPKRNIGYCHLK
                     DISLSLATKEFLSMISNNI"
     gene            9918..10475
                     /locus_tag="KR294_002857"
     CDS             9918..10475
                     /locus_tag="KR294_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH0240920.1"
                     /translation="MSDSEYPQMKTLETRNCILRPASLDDVEDFFDCYKNKIVVKHLP
                     FSEHKSLEDTRKFIKSFFLNPYKKGKIGHFAIVYKRDNKVIGNMGFNNINPKALEAEI
                     GICINPSYWGHDFATEITKRVIQYGFRELNLNKIIAITYEENQNSTKSLDLLGFKCTG
                     KYIKKIHTGNTVKNVPCYQYELKKQ"
     gene            complement(10714..11574)
                     /locus_tag="KR294_002858"
     CDS             complement(10714..11574)
                     /locus_tag="KR294_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBH0240921.1"
                     /translation="MKKQKSPILLEMLGLFFGCISMSIGINMFLKPHTIAPGGLSGLS
                     LVLNKVTGLPVSAIMLIIGVPLVILAFRIMGTKNSLKTLFGTVVFSAIVQLTDPLSKL
                     RFTNDLLLSSIAGGILVGIGLGIMFKSDASTGGTDLIALILSKKFPGIKATKFMSCLD
                     GMVVISSGIVNRSLETALYSGIALCVLIKIADMIMEGFDHSKAFFIISDEPESLRQAI
                     TEELDRGLTILDGKGGYTRENKEVLLVVVSKKQELYLKRLVKRTDPTAFVIVTDVHEV
                     LGEGFKNLEN"
     gene            12067..13470
                     /locus_tag="KR294_002859"
     CDS             12067..13470
                     /locus_tag="KR294_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH0240922.1"
                     /translation="MHKPSYKTVFHSYIIFFMIFICLILTVIGIFLSLITIQKPNGEF
                     IRSDWPKKFTENFNEQIVFIDNKPQVKQSGLEKLRENQLWLQILDSSGNRVYGFLEPK
                     EHKDYYSNSELLALANQNNSSNGTVYFNTIKNNKNDYIYIIYFPLNISKVNMFFDGGK
                     FIGGKSIVFSIIGIIFLIILVSGIAYGYWVTKCISNITSAVSDISKRSYLPVNIKGVF
                     ADIYNSLNILNEEIHRSDEIQNKTDIMREEWISNITHDLKTPLSPIKGYAELLTDSST
                     NYSPEKVYKYASIMLKNIEYTNTLINDLKLTYQLKNGIIPLNKNNYDLVRFLKELSID
                     ILNYPEYESNIVEFKSNIDNINFDFDCTLLKRAFSNLIVNAFTYGDKNTKVCVHITLN
                     ERIEIIISDNGKGMSREEASNLFNRYYRGSNTKQKIEGTGLGLAITKQIIEVHGGNIS
                     VESIPGLGSSFYITFPI"
     gene            13689..16166
                     /locus_tag="KR294_002860"
     CDS             13689..16166
                     /locus_tag="KR294_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HBH0240923.1"
                     /translation="MKIILKYIFTNIKERKIRTAVMLLSIVLSTVLLFVSFSIGLSYE
                     SAQRKMAKGMYGTATISVQSKNPDILTNLEDIPDLNAIKSKVGVLESSAIYNKGGYYE
                     EFSLISADLSQLNKINKPRLENGDSITDFSGDKIILPNRFTSKYKIKKGDSITLQIYG
                     KSYTFQVSDIASYDTVFLRNTRGVNALLPKETLSKIINKGSGYTRVLIESEEEITENL
                     VNKLSKELSTEKYMVSNTINETKIISDARQKTMPFFLISFFALTLSIFIIYSSYKVIT
                     LERLPFIGTFRSIGANEKTVTRILMLESILYGSIGGLIAIPIGVVVLNLMLHGLGNSL
                     EQGISIPVVISPIGVIISVIVAIIVSSFSAYIPVKKASHLPIKNIVLGTVEEKNVSNR
                     SILFIGSIMFILSILLPRISPENTLYLAGGFSLLGLIVATIVLIPLITDIMSIVFEFV
                     YKNILGNEGKLAARNMKNNKNIIQNITLLFISISAVIAISVVGNFVKTYITDVFRDAE
                     LQGFADGKMNEEFIEDVRHMDGIKKILPLYVMNNEISGNGVTLSRLEGTDNIKLYNSM
                     FGINYTNFEIKKQVIEAFNDKRSVILNEDTLKKVGLSIGDTITLSNDKYDFSYKIVGS
                     FKSRANDVEAVIPSHYAVNDFDKTNYGFLVYTAVNPDAVMIQIRYLFGDTYNWSRTVE
                     EFNNDSLNTISSFLSPMNKMTYFIFLLATVGIINNLLINYIQKRRSIAMYKSIGLSNK
                     QNIKVTLIEGFTSGLLGAVIGIVISILEIQTIFIVAGPKISMKPDLDFKTFIIVGLLG
                     IIVTLIGSIVPIIKGKKMKLIEEIKFE"
     gene            16181..>16854
                     /locus_tag="KR294_002861"
     CDS             16181..>16854
                     /locus_tag="KR294_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0240924.1"
                     /translation="MKITHNSLAVEAKNIIKEYKIGNTTTRVLKEVSLQVMKGEFVSI
                     MGQSGSGKSTLLYILGGLDTPTSGKVYMNGADISHFNDEKMSIIRRRNIGFVFQFYNL
                     IPNLNVEENIMLPLLLDGKNLKDYKNQLDEILDIVGLTDRRKHTPRELSGGQQQRVAI
                     ARALIGKPEILFADEPTGNLDSKTGIEIIDLLNKINRDNGQTIIMVTHSPEAAKSSSR
                     TITVSDG"
BASE COUNT         6456 a         2051 c         2431 g         5916 t
ORIGIN      
        1 ttctaattca atttcaatat tatcttcact attcatcata ctatctaaag tgtgacatat
       61 tttagaacaa aatataacta tttttttatg aagtaaaaat attattaatg ctataaatcc
      121 acaaagtacc attgtatata ttaataatag agcaattagt tttaaatcac cagttattag
      181 ataaattgag atactaaata aaatagctgt aaaaattata ccaacagcaa ttattaaata
      241 aatagaacta aaagaaaatt ttttaaaatt catttctttc acctaaccac atatatccca
      301 taccatatac cgttttgata tacttaagat tgtctttttc aattttgctt ctaatcctac
      361 ttataacaga tgttaaagta tgttcatcta caaagttagc atctatatcc cagagttttt
      421 ctaaaagtac tttccttgtt aaaatacttt taggattttc agtaagcagt tttaaagtac
      481 gatattctaa tggtgtaaat ataatttgat ttccatttat attggcagat aactcagaaa
      541 agttaatttc aagatatcca tccttatagt aatcttgttt tgtttttatt gtaagatgat
      601 ttaaaaaagc tttaattttt tgtttaaata tattgatatt aaatggtttt gttatataat
      661 ccaaagctcc aagttcatag cctttaatca tatcacattc catatcatta gcagttaaaa
      721 aaattattgg tatattgtaa ttttccttta tttcattaca taattcaaac ccacttttat
      781 ctggtaaatt aatatccaaa attattaaat caaattcaca ttcaaaaata gactttagtg
      841 cagatttagc tgtaaatttt gaagtaatta tatatccatc ttcaattagg ttatatgata
      901 gagttttatt taatatagaa tcatcttcta ctactaatat tttttccata cagttactcc
      961 ttttagttta atattttata atgtcaatta tagactaaaa acattgctga attgttataa
     1021 acgagaaaaa gtatttaaaa atttatatat ttaataaaga acctgtccta tgataaattc
     1081 tagtacagat tctttattaa ataaaattat ttcaaccaag atggatttcc aggtataaat
     1141 attcttttac caaattttga agtatactca tctaaagctt tttgaataag ctcattatta
     1201 cccttaaatg aagtagtatt ctttatagtt tcgagatttt ggctaaatgg gcaagcagat
     1261 atacacatac cacaatctgt acctaaatat ctccatttaa tatagcatgt ctcatgttca
     1321 attacccaat tatattttcc atcatcacca attttaatat cattagaaag cgaatgagaa
     1381 gggcagttaa aagagcattt tttacagacc ttacaaaaat cttctagtcc aaaatcaaca
     1441 tattcatctt ctaaaagagg aatatctgta gtaacaacac ctaatctaag tctagagcca
     1501 taatctttat ttgtaagtat agcatttctt cctatatctc ctaaaccagc atcacgagct
     1561 ataaaaacag gcattactaa ataattagca tccatatgat ttctagcatc atatcctaaa
     1621 tttcttatat agtaacttaa aatcatgccg acgatagatg catccacata gcactttgat
     1681 gtttctataa cttcacatat cattggagct ctatttatca tttctttatc catctcacat
     1741 ccaaatacaa ttgcatactt atgagttaga ttaatttctt caccgtaatt ttcttcatgt
     1801 ctacccctat ttgtataaat atgatagtct tttaatttag ttataccaac tacagaagct
     1861 ccatactgct ttgcaagacc cttaattttt tttgtcattg actttgcatc tacatctact
     1921 ttagtatcag aaacttttcc ttcgcataaa gatttgatat cagataaaaa atcgaatgca
     1981 ctacttgcca ttggagagtt taactcattg taagtcattg ttccttcact acataaattt
     2041 ggtctatttc ttatactatc atcaatttct tttttgtcag gatttttctt ataatagtca
     2101 ttataagcag tactatcttt tttgtaattt gctcttgcaa acatagtatt tctctcatca
     2161 acccttttca attctattcc ccctagtaaa aatatattta aaaaatataa ctttattgtt
     2221 gtataattta attatataag aataaagtta tattttcaat ttaagcgtaa ttaaattggg
     2281 aaatatataa ctatatgctt gattataatg tttttatttt gaaaacaaat ttaaatacaa
     2341 tctttttagt gaaataaata aaattaaaat atttttagta tgataatgca agaaaataat
     2401 tatttatcta aaaaatctaa aggagagtaa aattgaactt attaattatt gaagatgata
     2461 taaacttaaa tgaaggtctt ttttatgcat ttgagaatga tggatttaat gtatttaagg
     2521 cttatacaaa acaagaagga ttaaatatat ttaatagtaa aaatatagat tttataatct
     2581 tagactgcaa tcttccagat ggagatggat ttgatgtatg tcaaataata agggaaaagt
     2641 cagatatacc aattataatg cttactgcaa gagactcaga aattgatgaa gtaaaaggat
     2701 tagaaatagg gcttgatgat tatattacaa aaccattttc tttatctgta ttaaaggcaa
     2761 gagtcaaagt agcaataaga aaaaaatcga ataataaagt aatatattcc aatggaataa
     2821 aattggacca aaagttacta aaagtatata aaaataaaga atgtttggaa cttagctctg
     2881 tagaatataa gcttctaagt tatctaattg aaaataaagg tcaaatatta ttaaaggaac
     2941 aaattttaca ccatatttgg gacagcgaag aaaattatgt tgatgataat attgtatctg
     3001 taaatataag aagacttaga gtaaaagtag aggatgaccc atctaatcca aaatatataa
     3061 aaacagctta tggaatgggt tatttatgga atgaggtaga ataatatgtt tatattagcc
     3121 tttataatat gtacagttgt tatatttata gtatctacta aaataaatcg aaaaagatat
     3181 gatgaattaa atttgatgtt aaatcaaata ttggaaggta aagaagttac ttatccagat
     3241 acaaaggata caagagcgtc aaaaatttct caccaagtaa aaaaaattaa ggatatgata
     3301 gaaatagagg tagaacagtc aaagtcagaa aaagaagcga ttaaaggttt aatatcaaat
     3361 atgtcacatc aattaaaaac tccactttca aatataacca tttattgtga acttctggag
     3421 aatataaata tttccacatt acagaagaag gagtttttac aaaagatgaa aaatgaaact
     3481 tttaagattg actggctgtt acaatcctta tttaaaatga ctaaattaga ggatggagtt
     3541 atagaatttg aagtagaaga actactaatt aaagatactc ttattcaaag tatcagtact
     3601 atctttaata aagcagaagc taaaaatata aggataaatc tcgaaccatt ttcagacata
     3661 aaattagttc ataataaaaa gtggaccata gaagcaattg taaatgtttt agaaaatgca
     3721 ataaaatact caccatcaga tagcacgatt actatttctg taataaaaat ggaactatat
     3781 acgaagatta ctattaaaga tgagggaata ggtattgata gtagagaact aaatgatatt
     3841 tttaaaagat tttacagaag taaaaatgtt gaaaaccaaa atggcacagg gattggtcta
     3901 tatcttacaa gattaatttt agaaaaagaa aatggaaaca ttatagtaga atctaaacta
     3961 ggaagtggat gttgttttag tatcttctta cagaattgta agagtttaaa ctaattttgt
     4021 aggatgagtg taattatcgt cacttacaat attttataga acatatatct gtattgaaag
     4081 gagaaattaa atgagtatat tagtgacgaa taatttagta aaacactatg gaaaaggtga
     4141 gactaaagta aaagccttaa atggagtaag tatagaaatt gaacgagata catttactgc
     4201 tatagttgga acttctggtt ctggaaaaag cacattgtta aatattatag gtggattaga
     4261 taatccaacc tcaggtgatg taataattaa aggaaagaac atatctaaaa taggaaaaaa
     4321 agatttgaca gtgtttagaa gaagaaatat aggatttata tttcaaaact acagtttaat
     4381 gcccgtatta aacacttatg ataatatagc tcttcctgtt acattagata aaggaaacca
     4441 tatagaccat gaatatattg aaatgctgat gaagacattg ggaatttggg ataagcgttt
     4501 aaaatttcca agcgaactat ctggtggtca acaacagagg gtagcaattg ctagagcttt
     4561 ggcaaataaa cctgcgctta tattagcaga tgaaccaaca ggaaatctcg atagtaaaac
     4621 tacaatggaa gtggtatgtt tattaaaaga aagtagtgca aaattccatc aaacgatact
     4681 tatggtaaca cacaatgaaa atatagcaca agtatgcgac tcaattatcc atattgaaga
     4741 tggagttgtg gttaatactg gtggtgaatt actatgatgt ctctagtaaa attttcaatt
     4801 caatatataa agcattataa aaaacaatct atatctatag ttttaagcat agtactatca
     4861 gtagcattat tgacgggaat tggttcttta gttcatagtg cagacaaaag tagaattgaa
     4921 aagataaggg aagatagtgg agattatcat tatttctata aagtagataa ggaacaactt
     4981 aataaaatta aagaaaataa aaaatcaaag gaatacactg tagatagact tggcgttaca
     5041 aaacctaaaa atcagataga tgaacctttt attatagaat ttttaaatgc tgattcttca
     5101 tatttagaca tgacaggtag aaaattatta aaaggaactc ttcctagtaa agatggagag
     5161 atagtacttg acacatattc tctaaacaat ttaaatgtaa acaaagaaat tggaacagaa
     5221 atcaatttag atggtaaaat ctataagtta tgtggtattt tatcaagtct ttcaaaccca
     5281 gaaactgctc tggagggatt tgtaaacgat tattttcagc ctaaagaaaa ggattcttat
     5341 atagtttatg taaaatatga tgaaaataaa aatattaaaa agcaaaatta taaatttatg
     5401 aaaaaattca acatatcaaa agaaaaaact tatataaact ggtctctttc agttgaattt
     5461 ggagtaaaac caccaaaaaa tatagaaaaa tataatatat ttgagttctt aaaaaattta
     5521 gaactaaata caaatgcaat tatattgctt gttggagtgt ttggtgcagc agcagtatat
     5581 agtattttcc atgtttcaat acttcagaga atatcacaat atggggtttt agaagtatta
     5641 ggcgctaata ataaacaact tttatttcta ctatttttag agttattttt actttttatt
     5701 gttggatttc ctataggttg cttcttaggt attggagtag cgtctacaat atatgaacaa
     5761 tttccacata tatttttgag tagtgatatt gttccaggag cattttttat aagtgaaaaa
     5821 tctatttatt taggcttttt atttatctta ttgttgttaa ttttaattgc tgtacgtgtt
     5881 gtacatcagt tgaataaata ctctagtata gaatctatga aaaactttaa gattactaat
     5941 aagaaaaaga gaatattaga aagtgtaaaa cactctaaca tgacaaaagt attatctcat
     6001 aaatacatga ctcaaaaaaa gggaatgttt attggaattt tgttttcatt atcacttggt
     6061 ggaattatat ttctatgttc tagttactct atacagctta ctaaaaataa taatgaactt
     6121 acaatgaaag ctgatgatgg tttaaattct gactaccaaa taactatgca aacaacagat
     6181 tttgatgtag gtataccaaa agataaaatt tcaagattaa acaatgttga gggaatatca
     6241 aaagtctatc cagtaagata tttatttgga gctatgcaaa ttaaagaaga acaactattt
     6301 tggaaaaatt tctttaaacc tcttgaaaaa gattacagga taaagacttt ttttgatggt
     6361 atttgtacaa agcaaaatga aggtggctat cttttaaaaa caaatattta tggttataac
     6421 aatggtatgt tagaaggatt aaattcttat attatagatg gggagattaa tacccatgat
     6481 atggttaaaa ataataaggt tatagttaga ctacctatgg atggaactgg gatgtatgat
     6541 gcagttgata taaatccagg agatacaata aaagttaaag tgccaaagac aatgaaacca
     6601 acagatgaaa ttgttaaatt taaagaagaa aataagaatg attatacaac aaaagaattt
     6661 gtagttgctg ctactgtaaa acgtgtgatg gcaaataaca tatatttcat tggtgattat
     6721 ggtatggata tagttatgac gaatgggcaa atgaaaaata actttgatat cgaaaattat
     6781 aattcagtaa gtataaaaaa gacagaagat agtaacagtg aggaattgtc tgagaacata
     6841 aaaagtgttg taagtgatgt aaaaagatgt atcgtaacag attataccat tgctattgaa
     6901 aaaaataata cctacttaaa tcaaaaactc ttatttatat atggtattgt atttgtactt
     6961 cttgcaataa gtttgttcca tataatcaat acagtaagct acttaatttt ttcaagaaga
     7021 catgagtttg gaattttaag agctatgggt attacggata ataagttttt acttatgatg
     7081 ataagagaag gttttttata tggattctat gcaagtatta taatggtaat tggaagtgtt
     7141 attggacaat ttatgattta ttttatggta aaacgtgtat atttatatat aaatccaatt
     7201 cttaaaataa atacacctct atacataggt atgattattt taaatatcac tattagtata
     7261 gttgctgtaa ttattccagt aagacaaatt ttgaagagtg atattatttc agaaataaat
     7321 aagaattaga gttatataaa tttttaagat tatataactt tctgacaatc ttgtttaaat
     7381 tatttaaata tatcttatct gtgaacatta aataaacctc ttaatagata taactcttga
     7441 aaagtcatat ctattaagag gttttaataa attttcatgt taatatatat aatccaaaaa
     7501 aattaaatct tattaaaaca tactattttg tatagttatc gaaatatcct tgtatgtaaa
     7561 taataggagt acccttatct ccacttccag atgttaaatc tgctaaagaa cctataaggt
     7621 ctgttaatct tcttggagta gtaccttgag aaaccatgtt tcctgttaaa tcatcagatt
     7681 tattatcttt ttcaactatg tattttgaaa ttgcttcttt taactcatca ccagataagt
     7741 cagcaaaatc attatctgct aagtatttta attttacttc gtttggagtt ccctctagcc
     7801 cttttgtata agcaggagat actactgggt cagctaattc ccatatttta cctacagggt
     7861 ctttaaaagc tccatctcca taaaccatta cttctacatc tttccctgtt atttctttta
     7921 tattaccttg gattttgttt acaacttcat cacaatttat agggaataat tttactgttt
     7981 cttctgtagc tttgtttgaa cctaaaagtc catactggtc attgtaacca ctaccatcta
     8041 cacttgctgt cattatatca tcaagtgaat atactttttt agctccattt tgtcttaaaa
     8101 ttctctttgt tctttgtctt gtatgtatat cacaagttaa aatacttgtt gtatagttaa
     8161 gaatagtttt tggattgttt gcaaatacta tttctacctc tgcaccacaa tccttgatta
     8221 aattcttata ataatcaaca taatctacac cagtaaatgt atgcttgtta tatccaaata
     8281 gttctctgta tttttcttct gttaaaacat ctgaccaagg atttattccc ttatcatcaa
     8341 gttcatcaat acttattaag tgatttccaa cttcatcaga agggtagctt aacattaata
     8401 cgacttttct acatcctttt gcaattcctt ttaaacatat agcaaaacga tttctactta
     8461 aaattgggaa tataacccca acagtatcat ctccaaattt atcttttaca tcttttgcaa
     8521 tattgtcaac gtgagcataa tttccctgtg ctctagctac aacagcttct gtaacggcaa
     8581 ttacatcttt gtccctaact tcaaagtttt cactttttga cgcatttaaa acagaatcaa
     8641 caactatttt aactaagtca tctccttgtc ttataatagg tgctctaacc cctcttgaaa
     8701 cagttccaac taatctatcc attatctaaa atcctcctaa agaattaata ttgtcatatt
     8761 agtaccatgt atattataat tcaaatataa ttataagtaa aataaataat actaatattt
     8821 gacataagga gtaattatat atgaatataa aacttgaact ttataaggtt tttaatgcag
     8881 ttgtaaataa taagagtttt tctcttgctg ctaaggaatt gtttatgtca cagccagctg
     8941 taagccagtc aataaagcaa ttagaagaac aattagatac tttattattt tatagaaaca
     9001 ataagggagt aaaattaact ccagagggga aaattctaag tgaacatgtc actactgcat
     9061 taaagttaat atcatcagga gaagatagaa taaataaatt taaaaaatta gaatacggtt
     9121 ctctgaaaat aggagtagga gatacagctg cacgtttttt cttgttaaaa tatttagaaa
     9181 tttttcataa gaagtatcca catatacatg tatctacaat aaatagaacg agtagagaac
     9241 ttatatcttt actcaaagat gggaatatag atatagcaat tataaacatg ccaatagaag
     9301 atgatacact aaatattgtt gagtgtattg aaatacatga tatatttgta tgtgcaaatg
     9361 attacataga atacaaaggt aggaaaatat cattggaaga attaaacaca ttgcctttaa
     9421 taatgctaga aaataaagca aattcaagac tttatgtaaa tgaatatttt ttatcaaaag
     9481 gtataaaact aaacccggat atagaattgg gttctcatga attactttta gaatttgcgt
     9541 atataaatct tggagtgtct tgtgttatag aagaatttag catagattat ttggaaaatg
     9601 agaaattgtt taaattagat ataaaagagc caatacctaa gagaaatata ggttactgcc
     9661 atttaaaaga tatatcttta tccttagcaa ccaaagaatt tttaagcatg atatctaata
     9721 atatataatt tagaatacat atttcacaag taatttaata taaaaataga gataaattcg
     9781 taaatttgaa agattcatat agtaattagt ttttattaaa aataaaaata aggttaattt
     9841 gagaacattt atataattaa tatcgtattt taaatatgaa cagtatattt agattaatgt
     9901 ataaaggggg attagaaatg tctgattctg aatatcctca aatgaaaacc ttagaaacta
     9961 gaaattgtat actaagacct gcatcattag atgatgttga agattttttt gactgttata
    10021 aaaataaaat agtagtaaaa catttaccat ttagtgagca taaatcttta gaagatacaa
    10081 gaaagtttat aaaatcattt tttctaaatc catataaaaa agggaaaatt ggccactttg
    10141 ctatagtata taaaagagac aataaagtta ttgggaatat ggggtttaat aatataaatc
    10201 ctaaagcatt agaagcagaa ataggtatat gtataaatcc aagctattgg ggacatgatt
    10261 ttgctactga gataacaaaa agagtaatac agtatggatt tagagaacta aacttaaata
    10321 aaataattgc aataacctat gaagaaaacc aaaattctac aaaatcatta gatttattag
    10381 gatttaaatg tacaggaaag tatatcaaaa aaattcatac tggaaatact gtgaaaaatg
    10441 ttccttgtta tcaatatgaa ttgaaaaaac aatagatata atcatttaat atctatgctg
    10501 gttatttagt aatgattgtt ttctaaataa aatttcaata aagtggttgc ctcaaaatat
    10561 agataatcct gtttttattg ttaaaatact gaaaatgcat ttgattttat acaaaaaaga
    10621 gtgtctcatg aactaaaaag tttatgagac actctttttg aataaatcgt attttaatta
    10681 aaatagtata tatacttaaa atattaattt ttattagttc tctaaatttt taaatccttc
    10741 tccaagaacc tcatgtacat ctgtaacaat aacaaatgca gtagggtcag ttcttttaac
    10801 taatctcttt agataaagtt cttgtttttt agaaactacg actaatagaa cttctttatt
    10861 ttctctagtg tatccacctt taccatcaag aatagtaaga cctctatcaa gttcttcagt
    10921 tatagcttgt cttaaacttt caggctcatc agagataata aaaaatgctt ttgaatggtc
    10981 aaatccttcc attatcatat ctgctatttt tattaataca caaagtgcta taccagagta
    11041 aagagcagtt tctaaactac gatttactat accagaagat ataacaacca ttccatctag
    11101 gcatgacatg aattttgtag cttttattcc tgggaatttc ttactaagta tgagtgcaat
    11161 taagtctgtt cctccagtag aagcatctga tttaaacatt attcctaaac ctataccaac
    11221 taggattcct cctgcaatag aagacaataa taagtcatta gtaaatctta gttttgataa
    11281 tgggtctgtt aattgaacta tagctgaaaa tacaactgtt ccaaataaag tttttaatga
    11341 attttttgta cccataattc taaaagcaag tattactaat gggacaccta taattaacat
    11401 gatagctgat actggaagtc ctgtaacctt gtttagtact aatgatagac cactaagtcc
    11461 tccaggagca attgtatgtg gttttaaaaa catatttata ccaatactca ttgatataca
    11521 accaaaaaat agtccaagca tttcaagtaa aattggcgac ttttgttttt tcatataaac
    11581 acctccatga acttgtcaca atttaatatt ataacatatt tgaccagttt atattatata
    11641 aaatttcttg atataagcaa tttcaagtat ttcattattc ttaatatttt tgaattttta
    11701 tatagtgttt tcatattttt actgatgttg ttactctcct atgaagtttt tatatattat
    11761 aattttttta ttcttttata aagtatcccc tataaagatg gttctatgaa aattttctct
    11821 atactgttta acgtatatag agattttgtg tataattata aggtatttaa tggaaaaatt
    11881 tatcttactt ttatatgtta tcaaaaggat ttattaaata caacagatag cttgataaca
    11941 tataattata taaatataat ttatgtagat agttgtattt ttaaataaat ttttacatat
    12001 caataattat tgtctatttt atataagcaa taatcaaaat aaaagtttaa gaaaagagtt
    12061 gattaaatgc ataaacctag ttataaaaca gtatttcatt catacattat ttttttcatg
    12121 atttttattt gcttaatcct gacagtaata ggtattttct tatcacttat tactattcag
    12181 aaaccaaatg gggaatttat tcgtagtgac tggccgaaaa aatttacaga aaactttaat
    12241 gaacaaatcg tatttataga taataagcca caagtaaaac agtctggatt agaaaaactt
    12301 cgagaaaatc aattgtggtt gcaaatttta gattctagtg gaaatagagt ttatgggttt
    12361 ttagaaccaa aagagcataa agattattat tctaattctg aattattagc attagctaac
    12421 caaaataatt caagtaatgg aactgtatac tttaatacaa ttaaaaataa taaaaatgac
    12481 tatatttata ttatatattt tccattaaat atatctaaag tgaatatgtt ttttgatgga
    12541 ggtaaattta taggtggtaa gtcaattgta ttttcaatca tagggattat atttttaata
    12601 attttggttt ctggaattgc ttatggttac tgggtaacaa agtgcatatc aaatattaca
    12661 tctgctgtta gcgatatttc aaaacgaagc tatcttccag ttaatattaa aggtgttttt
    12721 gctgatatat ataatagttt aaatatttta aatgaagaaa ttcatagaag tgatgagata
    12781 caaaataaaa ctgatattat gagagaagag tggatttcaa atataactca tgatttaaaa
    12841 actccacttt caccaataaa agggtatgca gagcttctta cagatagtag tactaattat
    12901 tcacctgaaa aagtatataa atatgcttca atcatgttaa agaatataga atatacaaat
    12961 acacttataa acgatttaaa attaacctat caattaaaaa atggaataat ccctttaaat
    13021 aaaaataatt atgatttagt aagatttttg aaagaattat ccattgatat tttaaactat
    13081 ccagaatatg aatcaaatat agttgaattt aagagtaata tagataatat taactttgat
    13141 tttgattgta cactattaaa acgagctttt agtaatctta ttgtcaatgc ttttacatat
    13201 ggagataaaa atactaaagt ttgtgtacat ataacattaa atgaaagaat tgaaatcatt
    13261 atatctgata atggaaaagg gatgtcaaga gaagaagcat caaatttgtt taatcgttat
    13321 tatagaggaa gcaatacaaa acaaaaaata gaaggaactg gtttaggact agcaataacg
    13381 aagcaaatta ttgaagttca tggagggaat atatctgttg aaagtatacc tggattaggt
    13441 agctcatttt atatcacctt tcctatttaa ttaaggttaa ttaaggtcaa ataaaaaata
    13501 tattaaggtt gatagattat tatatttata tagtagttta tcaatctttt ttatttaagg
    13561 ggtgatttga ttaaaaatat tataaataga atgataaaag tatggaggag tctattagag
    13621 atttaattta gattaaagta taaaaatatt agattgaaat atcttagata aggaaagaag
    13681 gtgtaaattt gaaaattata ttaaagtata ttttcacaaa tattaaagaa cgaaaaatta
    13741 gaacagcagt tatgttattg tccatagttt tatcaacagt tttacttttt gtttcattct
    13801 caattggatt atcttatgaa agtgcacaaa gaaaaatggc aaaaggtatg tatggtacag
    13861 cgactatatc tgtccaaagt aaaaatccag atatattaac caatttagaa gacatacctg
    13921 atttaaatgc tataaaatca aaggttggtg tattggaaag ctctgctatt tataataaag
    13981 ggggatacta tgaagaattt agtcttatat cagcagactt aagtcaacta aataaaatca
    14041 acaagccacg attagaaaat ggcgatagta ttactgattt ttctggtgat aaaattattc
    14101 ttccaaatcg ctttacatca aaatataaaa taaaaaaagg tgattctatt actttgcaga
    14161 tttatggaaa gtcttatact tttcaagtta gtgatattgc atcttatgat acagtatttt
    14221 tgaggaacac aagaggtgta aatgcactgc tacccaaaga gactctatca aaaattataa
    14281 ataaaggcag tggatataca agagttctta tagagtcaga agaagaaatt acagaaaatc
    14341 tagtaaataa attatccaaa gaactttcta ctgaaaaata tatggtatca aatactataa
    14401 atgaaactaa gataatttca gatgctagac aaaagacaat gcctttcttt ttaataagtt
    14461 tttttgcatt aacccttagt atatttataa tatacagcag ttataaggtt attacattag
    14521 aacgtcttcc ttttattgga acatttagaa gtattggtgc caatgaaaaa actgtaactc
    14581 gtatattgat gcttgaaagt atattatacg gaagtatagg aggattaatt gctattccta
    14641 ttggtgtagt tgttttaaat ttaatgcttc atgggttagg aaattctctc gaacaaggaa
    14701 tatcaattcc agtagtaata tcacccattg gagtgattat atctgttata gtagcaataa
    14761 tcgtttcttc atttagtgca tatatacctg ttaaaaaagc tagccatttg ccgataaaaa
    14821 atattgtact aggaacagta gaagaaaaga atgtttcaaa tcgttctata ctttttatag
    14881 gaagtataat gtttatttta tctattttac ttccaagaat atcccctgaa aatacattgt
    14941 atctagctgg tggattttca ttactgggat taattgtagc tactattgtg ttgattcctc
    15001 ttattactga tatcatgtct atagtttttg agtttgttta taaaaatatt ttagggaatg
    15061 agggtaaatt agctgctaga aatatgaaaa ataacaaaaa tataatacag aatatcactt
    15121 tactatttat aagtatttct gcagttattg caataagtgt tgttggtaac tttgtcaaaa
    15181 cttatataac agatgtgttt cgtgacgcag aattacaagg ttttgcagat ggaaagatga
    15241 atgaagagtt tattgaagat gttagacata tggatggaat taaaaaaata ttacctcttt
    15301 atgttatgaa taatgagatt tctggtaatg gtgtaacatt atcaagacta gagggtacag
    15361 ataatataaa actatataac tctatgtttg gaatcaatta tacaaatttt gagataaaaa
    15421 aacaagtaat agaagctttt aatgataaac gttctgttat tttgaatgaa gatactctaa
    15481 aaaaagtagg cttatctata ggagatacaa taactctatc taatgataag tatgattttt
    15541 cttataaaat agtaggtagt tttaaatccc gcgcaaatga tgtagaagct gttataccat
    15601 cacattatgc agttaatgat tttgataaaa ctaattatgg ttttttagta tatacagcag
    15661 tcaatccaga tgctgttatg attcagataa gatatttatt tggagataca tataattgga
    15721 gtcgtacagt tgaagaattt aataatgatt ctttaaatac tataagtagt tttttgtctc
    15781 ctatgaataa gatgacctat ttcatttttc ttcttgctac agtaggtatt attaataatc
    15841 tactgattaa ttatattcaa aaaagacgtt ctatagctat gtataaatct ataggactaa
    15901 gtaataaaca aaatataaaa gtgacattga ttgaagggtt tacttcaggt ttacttggag
    15961 ctgttattgg tattgtgata tctatacttg agattcaaac tatctttata gttgcaggac
    16021 caaaaatttc aatgaaacca gatttagatt ttaaaacatt tattattgtt gggttattgg
    16081 gaattatagt aactttaata ggttcgatag tgcctattat aaaagggaag aaaatgaaac
    16141 tgatagaaga aattaagttt gaataattat ggaggttaat atgaaaatta cacataatag
    16201 tttagctgta gaagcaaaaa atattatcaa agaatataaa attggaaata caacaactcg
    16261 agtgttaaaa gaggtatctt tacaagtaat gaaaggtgaa tttgtttcta tcatgggtca
    16321 atctggttct ggcaaaagta ctcttttata tattttaggt ggtttagata ctccaacgag
    16381 cggaaaagtg tatatgaatg gagctgatat atcacatttt aatgatgaga aaatgagcat
    16441 aatacgtcgt agaaatatag gattcgtatt tcaattttat aacttaatac caaatttaaa
    16501 tgtggaggaa aatataatgc ttcctttgtt attagatggt aaaaatttaa aagattataa
    16561 aaatcaatta gatgaaatct tagatatagt tggtttaact gatagacgta aacatacacc
    16621 acgagagtta tctggtggtc agcaacaacg tgttgctata gctcgagctt taattggaaa
    16681 accagagatt ctatttgctg atgagcctac tggaaattta gatagtaaaa cagggataga
    16741 aataatagat ttactgaata aaataaacag agacaatgga caaactataa ttatggtaac
    16801 tcactcacca gaagcagcca aaagtagtag tcgtactatt acagtttcag atgg
//
LOCUS       DAEPKC010000087        16787 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.087, whole genome shotgun sequence.
ACCESSION   DAEPKC010000087 DAEPKC010000000
VERSION     DAEPKC010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16787)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16787)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16787
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.087"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            150..326
                     /locus_tag="KR294_002862"
     CDS             150..326
                     /locus_tag="KR294_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240925.1"
                     /translation="MEINVIEIFPKDKAKLNKIEMDKASWFVNIISKKYPKEALNEAF
                     STLEKELNISKANT"
     gene            500..1630
                     /locus_tag="KR294_002863"
     CDS             500..1630
                     /locus_tag="KR294_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003462216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HBH0240926.1"
                     /translation="MNNFEIKTRIKFGEGSLKALQELKNKNVLIITDPFMVKSKTIDK
                     ITSNLINSTYQVFEEIVPDPPIEVVVAGIEAFKSINPDVIIALGGGSAIDAAKSIMDF
                     SKKILKINEVEFIAIPTTSGTGSEVTSFAVITDSQKKCKYPLVSDDLLPDMAILDPEL
                     VKTVPNFITADTGMDVLTHAIEAYVSTNSNDFSDALAEKAIKLVFKYLIKAYKDGNDI
                     EAREKMHNASCLAGMAFNQASLGINHSIAHVLGGKFHIPHGRTNSILLPHVIEYNSSI
                     VGYTNTTYSATAKKYAQIAELVGLGSANIRISVRNLVNEIKKLQKEMNMPTKLTQCKL
                     SLEDITNEEREIAKLAIKDTCTLTNPKVPTEDDIINILKNIK"
     gene            1871..2221
                     /locus_tag="KR294_002864"
     CDS             1871..2221
                     /locus_tag="KR294_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003453843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMC domain-containing protein"
                     /protein_id="HBH0240927.1"
                     /translation="MTEESKQRVIQEYVPGKQVTLAHIIANPNEDIYKKLGLVLDKKD
                     AIGILTITPSEASIIAADVATKASNVSLGFIDRFSGSVVISGDVSSVESALNDVLEVL
                     GNMLNFSSTKITRT"
     gene            2229..2678
                     /locus_tag="KR294_002865"
     CDS             2229..2678
                     /locus_tag="KR294_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EutP/PduV family microcompartment system
                     protein"
                     /protein_id="HBH0240928.1"
                     /translation="MKNIIFMGKTGSGKTTLCQKLDQLELKYKKTQSVELYNNAIDTP
                     GEYMENRNLYNALITTSADAKIIAIVYDATQEENYIAPGFASMFCKDVIGIITKINKA
                     TENEVNIAYERLSLAGASQIFKIDTVDNIGLEKLFKYLEKYKNIDEV"
     gene            2780..3355
                     /locus_tag="KR294_002866"
     CDS             2780..3355
                     /locus_tag="KR294_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBH0240929.1"
                     /translation="MGKKILLVDDEPLLRMDTKDILESHGYEIIGEASDGFEAVEMCK
                     KHKPDLVIMDIEMPILDGIKAGKIICKENIAGGVLLLTSFEDKEYVEKAKSIGAYGYL
                     VKTASEKSLIPTIEMCLNKVNEFEKMKKDLEKVNSKLNERKLVERAKGILIREFKISE
                     DEAYTRIRKLSMDKRTTMMEIAKMIIIGYDD"
     gene            3348..4757
                     /locus_tag="KR294_002867"
     CDS             3348..4757
                     /locus_tag="KR294_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase N-terminal domain-containing
                     protein"
                     /protein_id="HBH0240930.1"
                     /translation="MTNTIKKISTAQTYLNNNEIEKIIEVSKSLDLMASFYEADVFID
                     VLSKFDDEAIVVAHGRPKEKSMYCENVIGKKALIENEPGVIKCLKTGERVRDIKALTQ
                     EYKLVKQNIQPITLDDKVLAVLIVEKDISSEVKNEFNASEDEENKNLHQFIKLIGNND
                     FLVDNLNSAILIFDKNGKLKIKNRIATEIYKNLGFGYDIQDMHYNDLDIETNTFENIL
                     MDENYDETNEVSIGNMFFKIKTIYIKDDEFKVCKIVQDISDLKRKEEELVLKTVAIRE
                     AHHRVKNNLHTVISIIKKQSRLSQNDEVKQCLDNIINRVFAILSTHYLLSKEVDNNIS
                     IREGINLLVSNIQGGYLFSKDIDIRITGEDFKISGEKATAILLVINEILQNCYDHAFS
                     DREHGTIQILINKDNDYRNIAIIDDGIGFDSNNINKNSLGTYIIDSYITQMLKGNIER
                     KSSENGTEVLITIPTQINI"
     gene            4941..6374
                     /gene="eutA"
                     /locus_tag="KR294_002868"
     CDS             4941..6374
                     /gene="eutA"
                     /locus_tag="KR294_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004458698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase reactivating factor
                     EutA"
                     /protein_id="HBH0240931.1"
                     /translation="MREELLSVGIDIGTSTTQLIFSKLIVENTESNFSVPRISIVDKE
                     IIYKSKVYFTPLISNNEINGQQIKDIVENEYKKANISKEDIHTGAVIITGETARKENA
                     NDVLHTLSGFAGDFVVATAGPDLESIISGKGAGAHIYSKEHSTTIVNIDIGGGTSNIA
                     SFKRGEVTDTGCLDIGGRLVKIDKISKKITYISPKIDKIIKDNNLNLQVGTMATVENT
                     KPIVDIMVDLLMESIGLKKQTPLFDFIITNKSISIDENIKNVSFSGGVADYIYYDGEI
                     KDYFEYGDLGILLGQAIKNCEYLKKVNVVKSMETIRATVVGAGSHTTEVSGSTITYTS
                     EKFPLKNLPVLKLSIDEETGTSKQISEAIKNKLNWFKLENDLQKVAIAMIGKKNPTFL
                     DIQEYAKGFVDGMQQIIENDLPFIVIVENDMAKVLGQAIYALLNYEKEIVCIDSVKVE
                     NGDYIDIGKPIVEGKVLPVVIKTLVFN"
     gene            6392..7756
                     /locus_tag="KR294_002869"
     CDS             6392..7756
                     /locus_tag="KR294_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003454054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase subunit EutB"
                     /protein_id="HBH0240932.1"
                     /translation="MILNTKLFGRTYQFKGLYDVMAKANEEKSGDKLAGLAAESAEER
                     IAAKVVLSHIKLEDIRNNPAVAYEEDEVTRIIQDAVNEKVYEEIKNWTVSELREWLLD
                     SNTTSLDIRRISRGLTSEMIAAVAKLMSNMDLVYAAKKIKVTAHCNTTIGEQGTLSAR
                     LQPNHPTDDPDGILASLLEGLTFGIGDAVLGLNPVDDSVESVTKVLKRFEEVKQKYQI
                     PTQTCVLAHVTTQMEAIRNGAPADLIFQSIAGSEKGNEAFGFNGDTIEEARQLALKHG
                     TATGPNVMYFETGQGSELSSEAHHGIDQVTMEARCYGFAKKYEPFLVNTVVGFIGPEY
                     LYDAREVVRAGLEDHFMGKLHGLPMGVDVCYTNHMKADQNDMENLAILLTTAGCTYFM
                     GIPHGDDVMLNYQTTGYHETASLREMFGLTAIKEFDAWMEKMGFSKDGKLTELAGDAS
                     VLLG"
     gene            7769..8650
                     /gene="eutC"
                     /locus_tag="KR294_002870"
     CDS             7769..8650
                     /gene="eutC"
                     /locus_tag="KR294_002870"
                     /EC_number="4.3.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014952556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase subunit EutC"
                     /protein_id="HBH0240933.1"
                     /translation="MNEKDLKALVEQLVGQMLGELDTNVVSETVKKATEVVVDNNACI
                     DDITEVDIRKQLLVKNPKDAEAYLDMKAKTPARLGIGRAGTRYKTETVLRFRADHAAA
                     QDAVFSYVDEEFIKENNMFAVETLCKDKDEYLTRPDLGRKFSPETINNIKSKFGTNQK
                     VLILVGDGLSSAAIEANLKDCVPAIKQGLKMYGIDSSEILFVKHCRVGAMDHLGEELG
                     CEVICMLVGERPGLVTAESMSAYIAYKPYIGMAEAKRTVISNIHKGGTTAVEAGAHIA
                     ELIKTMLDKKASGIDLK"
     gene            8670..9323
                     /gene="eutL"
                     /locus_tag="KR294_002871"
     CDS             8670..9323
                     /gene="eutL"
                     /locus_tag="KR294_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003761789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutL"
                     /protein_id="HBH0240934.1"
                     /translation="MKNDVIRPNILGIKIISNISPEMAQKLELKSHHKSLGLITADCD
                     DVTYTALDEATKASEVDVVYAKSMYAGAANASTKLAGEVLGIIAGPSPAEVRSGLNAV
                     VDFLEYGATFISANDDDSIAYYAHCVSRTGTYLSEVAGIREGEALAYLVAPPLEAMYA
                     LDAAMKAADVKMCELFAPPTETNFGGALLTGSQSACKAACDAFAEAVKSVADNPTGF"
     gene            9334..10035
                     /locus_tag="KR294_002872"
     CDS             9334..10035
                     /locus_tag="KR294_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMC domain-containing protein"
                     /protein_id="HBH0240935.1"
                     /translation="MDAIGLIEVIGYVAAIEASDACLKSANVNIVRVDKVGAGIVTLT
                     ICGDVGAVKAALEAGEIAASRVGTLRTSHIIPRIHNEVTNALFKTKEPKVCEVSEDKE
                     KNFEITLEIADNVSKNLSEKENVILDVNENSGDTENLYSDIDKTNKKIETVDDSLTEA
                     NEEKIENTNDKEVLEQVKIENSDFDRDDLSKNSVKKLKAMAKKLDSSITYKDLNVLKK
                     EELINLVKKLSRRDR"
     gene            10038..11507
                     /locus_tag="KR294_002873"
     CDS             10038..11507
                     /locus_tag="KR294_002873"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetaldehyde dehydrogenase (acetylating)"
                     /protein_id="HBH0240936.1"
                     /translation="MTLLDKDLVSIQEVRTLVRRSKVAQEKLSKMSQEQIDKIVKAVV
                     DAAFNNATKLAKMANEETGFGKWEDKVIKNTFASMGVYETLKNTKTIGIIGEDKEANT
                     IDIATPVGVVAGLIPSTNPTSTVIYKTIISLKAGNTIVFSPHPNAKNCILETVNIISE
                     AAIKAGAPEDSILCITNPSIVGTNELMKHKDTNLILATGGEAMVRAAYSSGTPAIGVG
                     PGNGPAFIDKSANVKLAIKRIIDSKTFDNGVICASEQSIVIEKSMEETVLKELKNQGA
                     YVLNEEESERLAKFILRANGTMNPQIVGKSVEVIANLADLTNVPKNTKVLVARENKVG
                     HNVAYSREKLTPILAFYVEENVEAIMNRCREILLNEGAGHTFSMHVNDEELVKRFALN
                     MPVSRILVNTPSALGGIGASTNLVPALTLGCGAIGGSSTSNNIGPLDLINVKRVAYGI
                     KEIEELGRDKSQVEKSMFDSMDKEELINLLVQKLVKELA"
     gene            11603..11890
                     /locus_tag="KR294_002874"
     CDS             11603..11890
                     /locus_tag="KR294_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMC domain-containing protein"
                     /protein_id="HBH0240937.1"
                     /translation="MASANALGMIETKGLVGAIEAADAMVKAANVQLVGKEQVGGGLV
                     TVMVRGDVGAVKAATDAGATAAERVGELISVHVIPRPHFEVDAILPKVSAE"
     gene            12017..12778
                     /locus_tag="KR294_002875"
     CDS             12017..12778
                     /locus_tag="KR294_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin adenosyltransferase"
                     /protein_id="HBH0240938.1"
                     /translation="MGVLTENEVKRKIGKNKNNITEFYIEKGQIITPSAKSYLAERSI
                     ELKYVDKLSDVNNEPKEVVKEVVKEKKYKYTTVFGAKLDEKPEHMTQLNGNLLVFKDH
                     KRIILRGKIDSLESEILKVQILCQKLDMPKLVKELQEVLDFVRNIMRCEVLDEKLGDF
                     KLLGLTPQELREQSHYPKKYFGIGHEFPSYEMGEVVVAINSIRSNTREVELAAYEAFK
                     GEYGNVHREDLIKALNRLSSVFWIMIYKVRTNKYK"
     gene            12791..13420
                     /locus_tag="KR294_002876"
     CDS             12791..13420
                     /locus_tag="KR294_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate propanoyltransferase"
                     /protein_id="HBH0240939.1"
                     /translation="MENLLNEIVEEVITRVKKEAFIEVEASGRHVHLSREDVDKLFGE
                     GYTLTKLKDLSQPGQYACKERVTITGPKGSIKNVVVLGPCRNETQVEISLTDGSTLGL
                     KAPIKQSGDLEGTLSIKISTQYGEVELDKGLMVAKRHIHMTPKDAEKFNVCDKEIVEA
                     KVMGQRPLTFDDVVIRVSDSFKTYMHIDYDEANACGYSKGTVAKIIKKA"
     gene            13462..14187
                     /locus_tag="KR294_002877"
     CDS             13462..14187
                     /locus_tag="KR294_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02536 family ethanolamine utilization
                     protein"
                     /protein_id="HBH0240940.1"
                     /translation="MNYDNLVDLITEEIYKKINSNEIKISNKPKAVIVFEQDNNKFNL
                     LKDGFEIVEFDKSIRECEIVIVSRLCMRGLSNIALGNSTSDEERFILKMIMNGKKVYV
                     LDEGIEYKKYKDTAPKALYKKFMSFEDEICKFGVEIIKDLNVITKNKLNIKKELESTR
                     GSKKEDTKVLDKDILNLTSVESVKIDNEFSLDLRNKKLISEADLRKPTINGVKNILVN
                     KKSIITPLAVDFMRIHHLKLKKL"
     gene            14200..14472
                     /locus_tag="KR294_002878"
     CDS             14200..14472
                     /locus_tag="KR294_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EutN/CcmL family microcompartment protein"
                     /protein_id="HBH0240941.1"
                     /translation="MDIGKVVGNVWATRKDEKLCGQKLLVVKILKTKDTYKEGFMVAA
                     DNAGAGNGDLVLISKGSSARESIEKSHVPVDATIVGVVDSFEVFDE"
     gene            14465..15016
                     /locus_tag="KR294_002879"
     CDS             14465..15016
                     /locus_tag="KR294_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMC domain-containing protein"
                     /protein_id="HBH0240942.1"
                     /translation="MNKSIGAIEFKSIAKGIEVSNEMIKKSSVDVLYLKSICPGKFLI
                     IVGGETSYINECVDYGIKLGEGYIVDNFVINAISQEILDGFKNKYQKLDSIVSIGVVE
                     SSKICAGIKMLDKTLKSGDLVLVKLQLSFAIGGKLVYIVAGDLSSLEYALKESENVVR
                     EKEVIYKTVIPSVDSQIIKSLIK"
     gene            15028..16119
                     /gene="eutH"
                     /locus_tag="KR294_002880"
     CDS             15028..16119
                     /gene="eutH"
                     /locus_tag="KR294_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization protein EutH"
                     /protein_id="HBH0240943.1"
                     /translation="MSINEIIIYVMVVFMVLGAIDKCIGNKFGLGEQFEEGIMAMGSL
                     AVAMVGVICLAPVLADVLRPIVVPVFNILGADPAMFAGSLLANDMGGAPLALELAKDP
                     NAGLFGGLIVGAMMGPTIVFIIPVALGIIEKEDQKFLATGILAGIITIPIGAFVGGLV
                     AGFEVMMVLRNLVPIIIFAVVIALGLLKFENAMIKGFTYFGKGVVIVITLGLAAAIVE
                     ALTGIVVIPGMKPISEGIEIVGDIAIVLAGAFPLVFVITKVFNKPLMALGKVLGMNDV
                     SAAGLVASLANCIPMFGMMKDMDNRGKIINVAFSVSAAFVFGDHLGFTAGFNSNMITP
                     MIVAKLVGGITAVLLAMVIANKTLKKENV"
     gene            16121..16594
                     /locus_tag="KR294_002881"
     CDS             16121..16594
                     /locus_tag="KR294_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF861 domain-containing protein"
                     /protein_id="HBH0240944.1"
                     /translation="MDISNIDKNLIETLVRQIIEEKISGTKDTVDFVRNKDISGITSI
                     KLPTVKVSESDRLDTGNPSDVVYTKDLFTLEESPRLGCGMMEMKETTFDWTLNYDEID
                     YVIDGTLDIIIDGRKVSASSGELIFIPKGSKIQFSVPDYARFIYVTYPADWASQN"
BASE COUNT         6924 a         1882 c         3123 g         4858 t
ORIGIN      
        1 gatatttaat tgtatcagga caaatctcta atttcataga ttattaatat aaaatcatag
       61 gttagtgtga aaaagttgaa atttaaatat tttaaaagat aatttttttg aactaatagg
      121 tataacaaaa atttataggg ggattgcata tggaaatcaa tgttatagaa attttcccta
      181 aagataaagc taaacttaat aaaatagaaa tggataaagc tagttggttt gtaaatataa
      241 taagtaaaaa atatcctaaa gaagctttaa atgaagcatt tagtacttta gaaaaagaat
      301 taaatataag taaagctaat acataagctt tgattattga ttttatatac tattggtttt
      361 atacgctatg acttgacatt atattaatca aatagtatat ttttaaatat agcacaatga
      421 agtgttaaaa gagcaatgga gctccataga taaagtctat ggagcttttt tgcgtattta
      481 acttaaggag gataggactt tgaataactt tgagattaaa actagaataa aatttggaga
      541 aggctcacta aaagctttgc aagaattaaa aaacaaaaat gtactaataa taacagaccc
      601 ttttatggtg aaatcaaaaa caatagataa aataacatct aatttaataa actcaacata
      661 tcaagttttt gaagaaatag taccagaccc accaatagaa gtagtagtag caggaataga
      721 agcatttaaa tctataaatc cagacgtaat aatagcatta ggtggtggtt ctgcaataga
      781 tgcagcaaaa tctataatgg acttttctaa aaaaatatta aaaattaacg aagtagagtt
      841 tatagcaata ccaacaacaa gtggaacagg ttcagaagta acatcatttg ctgtaataac
      901 agatagtcaa aaaaaatgta agtatccatt agtgagtgat gatttacttc cagatatggc
      961 aatactagac ccagaacttg taaaaactgt accaaatttt ataacagcag atacagggat
     1021 ggatgtattg acacatgcta tagaagctta cgtatctaca aattctaatg acttttcaga
     1081 tgcactagct gaaaaagcta taaagttagt atttaaatac ttaataaaag catataaaga
     1141 tggaaatgac atagaagcta gagaaaaaat gcacaatgca tcttgtttag caggtatggc
     1201 atttaaccaa gcatcacttg gcataaatca ttctattgca catgtattag gtggaaaatt
     1261 ccatatacca catggaagaa caaactctat attacttcct catgtaatag aatataattc
     1321 atcaatagta ggatatacta acacaactta ctctgctaca gctaaaaaat atgcacaaat
     1381 agcagaatta gtaggacttg ggagtgctaa tataagaata tctgttagaa atttagtaaa
     1441 tgaaataaag aaactacaaa aagaaatgaa tatgccaact aaattgacac aatgcaaatt
     1501 aagtttagaa gatataacta atgaagaaag agaaatagca aaacttgcta taaaagatac
     1561 ttgtacatta actaatccta aggtaccaac tgaagatgat ataataaaca tattaaagaa
     1621 cattaaataa ctacatttta ttacatgtaa atataatatt atacaaatag ggaaaatgtt
     1681 tttaaaaata taaattatat attgacaaat ataaaacata aaactataat gaaagtatca
     1741 caaaggcgtg atactttagt agaaagcaat ggagcttctt aggaatatta atattattct
     1801 tatggagctc cttttatttt aatcaaatag ctttttaata aactatattc aaagaaagca
     1861 gggaataaat ttgactgaag aatctaagca aagagttatt caagaatatg ttcctggaaa
     1921 acaggttaca ttagcacata tcatagctaa ccctaatgaa gatatatata agaagttagg
     1981 attagtactt gataaaaaag atgcaatagg aatacttaca ataacaccaa gtgaagcgtc
     2041 aataatagca gcagatgttg ctacaaaggc ttcaaatgta tctttaggtt ttatagatag
     2101 atttagtggt tcagtagtaa tatcaggtga tgtaagttct gtagaatcag cgttaaatga
     2161 tgttttagaa gtcttaggaa atatgttaaa cttctcatct acaaaaatca caaggacata
     2221 ataatacaat gaagaatata atatttatgg gaaagacagg tagtggtaaa actaccttat
     2281 gtcaaaaact agaccagtta gaattaaagt ataaaaaaac tcaatcagtg gaactttata
     2341 ataatgcaat agacactcct ggtgagtata tggaaaatag aaacctatat aatgccttaa
     2401 taacaacatc agcagatgct aaaattatag caatagtgta tgatgccaca caagaagaaa
     2461 attatatagc accaggtttt gccagtatgt tttgcaaaga cgtaatagga attataacta
     2521 aaataaataa agctactgaa aacgaagtca atatagctta tgaaagacta tcactagcag
     2581 gagcaagtca aatctttaaa atagacacag ttgataatat tggacttgaa aaattattta
     2641 aatatctaga aaaatataaa aatatagatg aagtttaagg ggaaatattt ttttattcaa
     2701 aaatattatt aaagtatgat aaaataaaaa aatgtataaa ctattttaag aagatttaat
     2761 ctttaagcga ggtaggaaca tggggaaaaa aatactattg gttgatgatg aaccactgtt
     2821 aaggatggat acaaaagata tattagaaag tcatggctat gaaataatag gcgaagcaag
     2881 tgatggattt gaagctgttg aaatgtgtaa aaaacacaaa cctgatttag ttataatgga
     2941 tatagagatg ccaatacttg atggtataaa ggcaggcaaa ataatatgta aagaaaatat
     3001 agctggtgga gtacttttat taacttcatt tgaagataaa gaatacgtag aaaaggctaa
     3061 aagtataggt gcttatggat atttagtaaa aacagcaagt gaaaaatcac ttatcccaac
     3121 catagaaatg tgtttaaata aggtaaatga atttgaaaaa atgaaaaaag atttagaaaa
     3181 agtaaattct aaattgaatg aaagaaaatt agtagaaaga gcaaaaggta tacttataag
     3241 agagtttaag atttctgagg atgaagcata cactagaata agaaaattaa gtatggataa
     3301 aagaactaca atgatggaaa ttgccaaaat gattataata ggatacgatg actaatacga
     3361 taaaaaaaat atcaactgca caaacatact taaataataa cgaaattgaa aaaattatag
     3421 aagtatcaaa atccttagat ttaatggctt ctttttatga agctgatgtt tttatagatg
     3481 tactaagtaa atttgatgat gaagcaattg ttgtggcaca tggtagacct aaagaaaagt
     3541 caatgtactg tgaaaatgtt ataggtaaaa aggctttaat tgaaaatgaa ccaggagtta
     3601 taaagtgctt aaaaacagga gaaagagtaa gagatattaa agctttaaca caggaatata
     3661 aactggtcaa acaaaatatt cagccaataa cactagatga caaagtttta gcagtactaa
     3721 tagttgaaaa agatataagt agtgaagtta agaatgagtt taatgctagt gaagacgaag
     3781 aaaataaaaa tttacatcag tttataaaac ttattggaaa taatgacttt ttagttgata
     3841 atttaaattc agccatatta atatttgata aaaatggaaa attaaaaatt aaaaatcgta
     3901 ttgcaactga gatatacaaa aatcttgggt ttggatatga tatacaagat atgcattaca
     3961 atgatttaga tatagaaacc aacacctttg aaaatatatt aatggatgaa aattatgatg
     4021 agacaaatga agtttcaata ggtaatatgt tttttaaaat aaagaccata tacatcaaag
     4081 atgatgaatt taaggtttgc aaaatagtac aagatataag tgatttaaag agaaaagaag
     4141 aagaattagt tttgaaaaca gtggctataa gagaagctca tcatagagta aaaaataatc
     4201 ttcatacagt aatatctata ataaaaaaac aaagtagatt atctcaaaat gatgaagtaa
     4261 agcagtgttt agataacata ataaataggg tatttgcaat actttcgact cattatttac
     4321 tatctaaaga agttgataat aatatatcta tacgagaagg tatcaattta ttagtgtcaa
     4381 atattcaagg tggctattta tttagtaagg atatagatat acgtataact ggtgaagatt
     4441 ttaaaattag tggagaaaaa gcaacagcaa tacttttggt tataaatgaa atactacaaa
     4501 attgttatga ccatgcattt tcggatagag aacatggtac tatacaaata ttaataaata
     4561 aagataacga ctatagaaat attgctatta tagatgatgg aattggattt gatagtaata
     4621 atataaataa aaatagctta gggacatata taatagatag ttatataaca cagatgttaa
     4681 aaggaaatat agagagaaaa agtagtgaga atggtacaga agtattaatt actataccta
     4741 cacaaattaa tatttaaata ataactcatc tacaaagtag tagttttaat tgagcaaaga
     4801 ggcttaaggt tattaataga ttaagttaat tgaatgtatt tataaaaatt ataagtatat
     4861 attcaattta acaggtattt attataactt taagcctctt tgcttgttta agacatactt
     4921 aaattttagg aggtgagaaa atgagagaag agttattaag tgttggtatt gacattggaa
     4981 caagtactac tcagttaatt ttttctaaat taatagtaga aaatactgaa tcaaattttt
     5041 cggtacctag aataagtata gtagacaaag aaattattta taaaagcaaa gtttatttca
     5101 cccctcttat ttcaaataat gaaataaatg gtcaacaaat aaaagatata gttgaaaatg
     5161 aatataaaaa agcaaatata tctaaagaag atatacatac aggagcagta ataataactg
     5221 gtgaaacagc tagaaaagaa aatgcaaatg atgtacttca tactttgagt ggatttgctg
     5281 gggacttcgt tgttgcaaca gcaggacctg atttagaaag tataatatca ggaaaaggag
     5341 ctggagctca tatttattca aaagaacatt caactacaat tgtaaatata gacataggtg
     5401 ggggaactag taacatagcc tcatttaaaa ggggagaagt aaccgatact gggtgtttgg
     5461 atataggtgg aaggcttgta aagatagata aaataagtaa aaaaataact tatatatcac
     5521 ctaaaataga taaaatcata aaagataata atttaaatct tcaagtaggt acaatggcta
     5581 ctgtagaaaa tacaaagcca atagtggata taatggttga cttattaatg gaaagcatag
     5641 gactaaagaa acagacacct ttgtttgatt ttataataac caataaatca ataagtatag
     5701 atgaaaatat taaaaatgtt tcattctctg gtggagtagc tgattatatt tactatgatg
     5761 gagaaataaa agattatttt gaatatggtg acttgggaat tttacttggg caagcaataa
     5821 aaaattgtga ataccttaaa aaagtaaatg tagttaaatc tatggaaaca ataagagcca
     5881 cagtggttgg agcaggttct catactactg aagtaagtgg aagtacaata acttacacta
     5941 gcgaaaagtt tccacttaag aacttgccag ttttaaaatt atcaattgat gaagaaacag
     6001 gtacttcaaa acaaatcagt gaagctataa aaaataaact taattggttt aaactagaaa
     6061 atgatttaca gaaagttgct atagccatga taggaaagaa aaatccaacc tttttagata
     6121 tacaagagta tgctaaaggg tttgtagatg gaatgcaaca aatcatagaa aatgatttac
     6181 cttttatagt aattgttgaa aatgatatgg caaaagtgtt aggtcaagca atatatgcat
     6241 tattaaatta tgaaaaagaa attgtttgta tagacagtgt caaggttgaa aatggagact
     6301 atatcgacat tggaaaacct atagttgaag gtaaagtttt acctgtggta ataaaaacat
     6361 tagtttttaa ttaatagaag gaggtaagta aatgatttta aatacaaaat tatttggacg
     6421 tacttatcag tttaaaggct tatatgatgt aatggctaaa gctaatgaag aaaaatcagg
     6481 agataaatta gcaggtcttg cagcagaatc agctgaagaa agaatagcag caaaagttgt
     6541 tttatcacac ataaaattgg aggatataag aaataatcct gcagtggcat atgaagaaga
     6601 tgaagtaaca agaataatac aagatgctgt aaatgaaaaa gtttatgaag aaataaaaaa
     6661 ttggacagtg tctgaactta gagaatggct attggattca aatactacaa gtcttgatat
     6721 aagaagaata tcaagaggat taacttctga aatgatagca gcagttgcaa aattaatgtc
     6781 aaatatggac ttagtttatg cagctaaaaa gataaaggtt actgctcact gtaatacaac
     6841 tataggagaa caaggaacat tatcagcaag acttcaacct aatcatccaa cagacgaccc
     6901 agatggaata cttgcatcac ttcttgaagg tttaactttt ggtataggag atgcagtact
     6961 tggattaaat ccagttgatg actctgttga gagtgttact aaagtattaa aaagatttga
     7021 agaagtaaaa caaaaatatc aaataccaac tcaaacatgt gtattggcac acgttactac
     7081 acaaatggaa gcaataagaa atggtgctcc tgcagattta atattccaat ctatagcagg
     7141 ttctgaaaaa ggaaatgaag catttggatt taatggcgac actatagaag aagctagaca
     7201 gttagcctta aaacacggta cagctacagg acctaacgtt atgtattttg aaactggaca
     7261 aggttcagaa ttatcttcag aagcacatca tggaatagac caagttacta tggaagctag
     7321 atgctatgga tttgctaaaa agtatgaacc attcttagta aatacagttg ttgggtttat
     7381 aggacctgag tacttatatg atgctagaga agttgtaaga gcaggacttg aagaccactt
     7441 tatgggtaaa ctacatggct taccaatggg tgttgatgtt tgttacacta accatatgaa
     7501 ggctgaccaa aatgatatgg aaaacttagc catactatta acaacagcag gatgtacgta
     7561 ttttatggga atacctcatg gagatgatgt tatgcttaac tatcaaacaa caggatacca
     7621 tgaaacagca tcacttagag aaatgtttgg actaacagca ataaaagaat ttgatgcttg
     7681 gatggaaaag atgggattct ctaaagatgg taagttaaca gagttggcgg gagacgcatc
     7741 tgtattatta ggataggagg tatttaatat gaatgagaag gatttaaaag cattggtaga
     7801 acaattagtt ggacaaatgc ttggagaatt agatactaat gttgtgtctg agactgttaa
     7861 aaaggcaact gaagttgtag tagacaacaa tgcttgtata gatgatataa cagaagttga
     7921 tataagaaag caattactag taaaaaatcc taaggatgca gaagcttatt tagatatgaa
     7981 agcaaaaaca cctgcaagat taggtatagg aagagctggt actagatata aaacagaaac
     8041 agttttaaga tttagagcag accatgctgc tgcacaagat gctgtattct cttatgtaga
     8101 tgaagaattt ataaaagaaa ataatatgtt tgcagtggaa actttatgta aagataaaga
     8161 tgaatactta acaagaccag atttgggaag aaaattttct ccagaaacta taaataatat
     8221 aaaatctaaa tttggtacaa atcaaaaggt tttaatatta gttggagatg ggcttagctc
     8281 agctgcaata gaggcaaatt taaaagactg tgtgccagct ataaaacagg gtctaaaaat
     8341 gtatggtata gattcaagtg aaattttatt tgttaaacat tgtagagttg gtgctatgga
     8401 ccacttaggt gaagaattag gttgtgaagt tatatgtatg ttggttggag aaagaccagg
     8461 attagttact gctgaatcaa tgtcagcata tatagcttat aagccatata taggaatggc
     8521 agaagcaaaa agaacagtta tatcaaacat tcacaaaggt ggaacaactg cagttgaagc
     8581 aggtgctcat atagctgaac ttataaaaac tatgttagat aaaaaagctt caggaataga
     8641 ccttaaataa agtcgaggga gtgtagaata tgaaaaatga tgtaattcgt cctaatatac
     8701 taggaattaa aataatttca aatataagtc cagaaatggc acaaaaacta gaattaaaat
     8761 cacatcacaa aagcttaggt ttaataactg cagactgtga tgatgttacg tatacagctc
     8821 ttgacgaagc aactaaagct tcagaagttg atgttgtata tgcaaaatca atgtatgcag
     8881 gtgctgcaaa tgcttcaaca aaacttgctg gtgaagtatt aggaataata gcaggtccaa
     8941 gcccagcaga agtaagaagt ggtctaaatg cagtagttga ttttctagag tatggagcaa
     9001 cttttataag tgcaaatgat gatgattcaa tagcatacta tgctcactgc gtatcaagaa
     9061 caggtacata cctttcagag gtagcaggaa taagagaagg tgaagcatta gcttatttag
     9121 tagcaccacc acttgaagca atgtatgcac tagatgcagc aatgaaagct gcagatgtta
     9181 agatgtgtga attatttgca cctccaactg aaacaaactt tggtggagca ttacttacag
     9241 gttctcaatc ggcttgtaaa gcagcatgtg atgcatttgc agaagcagta aaatcagttg
     9301 cagacaatcc aacaggattt taaggatagt tagatggatg ctataggctt aatagaagta
     9361 ataggatatg ttgctgcaat agaagcttct gatgcttgtt taaaatctgc aaatgttaat
     9421 attgtaagag ttgataaggt tggggcaggt attgttactt taacaatatg tggagatgtc
     9481 ggtgctgtaa aagctgcttt agaagcgggt gaaatagcag cttccagagt tggtacatta
     9541 agaacatcac atattatacc gagaatccat aatgaagtaa caaatgcttt attcaaaact
     9601 aaagaaccta aagtctgtga agtttcagaa gataaagaaa aaaactttga gattacattg
     9661 gaaatagctg ataatgtatc gaaaaattta tcagaaaaag aaaatgtaat tttagatgtc
     9721 aatgaaaaca gtggagatac tgaaaattta tatagtgata tagataaaac aaacaaaaaa
     9781 attgaaacag ttgatgatag tttaacagaa gctaatgagg aaaaaataga aaacactaat
     9841 gataaagaag tattggaaca agttaaaata gaaaattccg attttgatag agatgaccta
     9901 tcaaagaaca gtgtaaaaaa acttaaagct atggctaaaa aattagattc ttcaataact
     9961 tataaagact taaatgttct taaaaaagaa gaattaataa acttagttaa aaagcttagc
    10021 agaagggata gatagttatg acacttttag ataaagattt agtatctata caagaagtaa
    10081 gaactcttgt aagaagatct aaagtggctc aagagaaact ttctaaaatg agtcaagagc
    10141 aaatagataa aatagtaaaa gctgttgtag atgcagcatt taataatgct actaaattag
    10201 ctaaaatggc aaatgaagaa actggatttg gaaaatggga agataaagta attaaaaata
    10261 cttttgcatc tatgggagtt tatgaaactt taaagaacac aaaaactatt ggaataattg
    10321 gtgaagataa agaagccaat acgatagata tagctacacc agttggagtt gttgcaggtc
    10381 ttataccttc aacaaaccca acatcaacag taatatacaa aactataata tctctaaaag
    10441 caggaaatac tatagttttc tctccacatc caaatgcaaa aaactgcata cttgaaacag
    10501 ttaatataat aagtgaggct gctataaagg ctggagctcc agaggattca atattatgta
    10561 taactaatcc aagtatagtt ggaaccaatg aattgatgaa acataaagat acaaacttaa
    10621 tactagcaac tggaggagaa gcaatggtta gagctgctta ctcttcagga acaccagcta
    10681 ttggagttgg accaggaaat ggaccagcat ttatagataa atcagcaaat gttaaattag
    10741 caatcaaaag aataatagat tctaaaactt ttgataatgg tgttatatgt gcatcagaac
    10801 aatctatagt aatagaaaaa tctatggaag aaactgtttt aaaagagctt aaaaatcaag
    10861 gtgcatatgt tttaaatgaa gaggaaagtg aaagattagc aaaattcata ttaagagcta
    10921 atggtactat gaatccacaa atagttggta aaagtgttga ggtaatagca aatttagcag
    10981 acttaacaaa tgtacctaaa aatacaaaag ttctagttgc aagagaaaat aaagttggtc
    11041 acaatgtagc ctattcaaga gaaaaactta caccaatact agcgttctat gttgaagaaa
    11101 atgtagaagc tattatgaac agatgcagag aaatattgtt aaatgaaggt gcaggtcata
    11161 cattctcaat gcatgtaaat gatgaagaat tggtaaaaag atttgccctt aatatgccag
    11221 tatcaagaat acttgtgaat actccttcag cacttggagg aataggtgca tcaacaaacc
    11281 ttgtaccagc actaacactt ggttgtggtg caataggtgg aagttcaact tcaaacaata
    11341 taggaccact tgatttaata aatgttaaaa gagtagctta tggaatcaaa gaaatagaag
    11401 aacttggaag agataaatct caagttgaaa aatcaatgtt tgactcaatg gataaagaag
    11461 aattaataaa tcttcttgtt caaaaactag tcaaagaact agcataacta aaataaacaa
    11521 tgaaacttat ggctatcgct ataaatttct aaaaatataa actataaaaa actataaaat
    11581 taaatttttg gaggataaga ttatggcaag tgcaaacgca ttaggaatga tagaaactaa
    11641 aggattagta ggagcaatag aagcagcaga tgcaatggtt aaagctgcaa atgtacaatt
    11701 agtaggaaaa gagcaagtag gtggaggatt agttactgta atggtaagag gagatgttgg
    11761 agctgttaaa gctgctacag atgcaggagc tacagctgcc gagagagttg gagaactaat
    11821 atcagttcat gttataccaa gaccacactt tgaagtagat gctatattac caaaggtatc
    11881 agctgagtaa tataagaata attataaaat ttaaattttg attgaaaaag aggctatctc
    11941 aaaaatgagt cttactaata aactcaatgt attttgaggt agtctttttt atacatctaa
    12001 taggagatgt gataaaatgg gtgttttaac agaaaacgaa gtaaaaagaa aaattggaaa
    12061 aaacaaaaat aatataactg aattttatat agaaaaaggt caaataataa ctccttctgc
    12121 aaaatcttat ttagctgaga gaagtattga gcttaaatat gttgataaac tttcagatgt
    12181 aaacaatgaa cctaaagaag ttgtaaaaga agtagttaaa gagaaaaaat ataaatatac
    12241 tactgtattt ggcgccaaat tggatgaaaa accagaacat atgactcaat taaatggaaa
    12301 tcttttagtt tttaaagacc ataaaagaat aatattgaga ggaaaaatag attctcttga
    12361 atcagaaata ctaaaggtac agatactttg tcagaaacta gatatgccaa agcttgttaa
    12421 ggaattgcaa gaagtattag actttgtaag aaatataatg agatgtgaag ttttagatga
    12481 aaagctaggg gactttaaac ttttaggatt aactcctcaa gaacttagag aacaatctca
    12541 ctatcctaaa aaatactttg gtataggaca tgagttccca agttatgaaa tgggagaagt
    12601 agtagtagct ataaatagta taagaagtaa tacacgagag gttgaacttg cagcctatga
    12661 agcatttaag ggtgagtatg gaaatgttca cagagaagat ttaataaagg cacttaatag
    12721 attatcgtca gtattttgga taatgatata taaggttaga actaataagt ataagtagtt
    12781 ggaggacata atggagaatc tattaaatga aatagtggaa gaagtaataa ctagagttaa
    12841 aaaagaagca tttatagaag ttgaagcatc aggaagacac gttcacttaa gtagagaaga
    12901 tgtcgataaa ttatttggag aaggatatac tcttacaaaa ctaaaagacc tatctcaacc
    12961 aggtcaatat gcatgtaagg aaagagttac aataactggt cctaaaggaa gtataaaaaa
    13021 tgtagttgta cttggaccat gtagaaatga aactcaggta gaaatatctt taacagatgg
    13081 ttcaactctt ggactaaaag ctcctataaa acaaagtgga gacttagaag gtactttaag
    13141 tattaaaata tcaacacaat atggtgaagt tgaacttgat aaggggctaa tggttgctaa
    13201 aagacatata cacatgactc ctaaagatgc tgaaaaattc aatgtatgtg ataaagagat
    13261 agttgaagct aaggtgatgg gtcaaagacc tttaacattt gatgatgtag taataagagt
    13321 gagtgacagt tttaaaactt atatgcatat agactatgat gaagccaatg catgtggtta
    13381 ttcaaaagga actgttgcta aaataataaa gaaagcataa atttaaccta ctatataaat
    13441 tacctctagg gaggatttaa tatgaattat gataaccttg tagatttaat aacggaagaa
    13501 atctataaaa aaataaatag taatgaaata aaaatatcta ataaacctaa agctgtgatt
    13561 gtatttgaac aagataacaa taaatttaac ttattaaaag atggatttga aatagtagaa
    13621 tttgataaaa gtataaggga atgtgaaata gtgatagttt caagactttg tatgaggggg
    13681 ctatcgaata tagcacttgg aaattcaaca agtgatgaag aaagatttat actaaaaatg
    13741 attatgaatg gcaaaaaagt atatgtccta gatgaaggaa ttgaatacaa aaaatataag
    13801 gatactgcac caaaagcact atataagaaa tttatgtcat ttgaagatga aatatgtaaa
    13861 tttggtgtag aaattataaa agacttaaat gttataacta aaaataagtt aaatataaag
    13921 aaagaactag aaagtactag aggttctaaa aaagaagata caaaagtttt agataaagat
    13981 attttaaatt taaccagtgt agaaagtgta aaaatagata atgaatttag tttggattta
    14041 aggaataaaa aacttatatc ggaagctgac ttaagaaaac caactataaa tggagttaaa
    14101 aacatattag ttaataaaaa aagtataata acaccattag ctgtagattt tatgagaata
    14161 caccatctca aactaaagaa actgtaagga ggtaatttta tggatatagg aaaagttgta
    14221 ggtaatgttt gggctacaag aaaagatgaa aaattatgtg gccaaaaact tttagttgta
    14281 aaaattttaa aaactaaaga cacatacaag gaaggcttca tggttgcagc cgataatgca
    14341 ggagcaggaa atggagactt agttcttata tccaaaggtt cctcagctag agagtcgatt
    14401 gaaaaatctc atgttccagt agatgcaact atagttggag tagtcgattc gtttgaggtg
    14461 tttgatgaat aaaagtatag gagctataga gtttaaaagc attgctaaag gtatagaagt
    14521 atccaatgaa atgataaaga aatcttcagt tgatgtattg tacttaaaaa gtatttgccc
    14581 aggtaaattt ctaataatag taggtggaga aacttcttat ataaatgaat gtgtagatta
    14641 tggaataaaa cttggagaag gatatattgt agataacttc gtaataaatg caatttcaca
    14701 agaaatatta gatggattta aaaataagta tcaaaagcta gatagtatag tctctatagg
    14761 cgttgttgaa agtagtaaaa tatgcgctgg aataaaaatg cttgataaga ctttaaaatc
    14821 tggcgactta gtattagtaa aacttcaatt atcttttgct ataggtggca aattagtata
    14881 tatagtagca ggagatttaa gtagtttaga atatgcatta aaagaaagtg aaaatgtagt
    14941 aagagaaaaa gaagtaatat ataagactgt aataccatca gtagacagtc aaataataaa
    15001 aagtctaata aaataatggg gggaattatg agtataaacg aaattataat ctatgtaatg
    15061 gtagtcttca tggtacttgg agctatagat aaatgtatag gtaacaaatt tggtcttgga
    15121 gaacaatttg aggaaggtat aatggcaatg gggtcacttg cagttgcaat ggttggtgtt
    15181 atatgtttag caccagttct tgctgatgta ttaagaccaa ttgtagtacc agtatttaat
    15241 atacttggag ctgacccagc tatgtttgct ggaagtttat tagctaatga tatgggtggt
    15301 gcgccacttg cacttgaact tgcgaaagac cctaatgctg ggttatttgg tggattaata
    15361 gtaggggcta tgatgggacc tacaatagta tttataatac cagttgcgct tggaataatt
    15421 gaaaaagaag accaaaaatt cttagcaaca ggaatacttg caggtataat aacaatacct
    15481 attggagcat tcgttggtgg attagttgca ggattcgagg taatgatggt tcttagaaac
    15541 ttagtgccaa taataatatt tgcagtagtt atagcacttg gattattaaa attcgaaaat
    15601 gctatgataa aaggattcac atactttgga aaaggtgtag taatagttat aactttagga
    15661 cttgctgctg ccatagttga agctttaaca ggaatagttg taatacctgg aatgaaacca
    15721 atcagtgaag gtatagaaat agttggagat atagcaatag ttttagcagg agcattccca
    15781 ttagtgtttg ttataacaaa ggtatttaat aaaccattaa tggctttagg aaaagttctt
    15841 ggaatgaatg atgtatcagc agcaggcctt gttgcaagtt tagctaactg tataccaatg
    15901 tttggtatga tgaaagatat ggacaataga ggaaaaataa taaatgtagc attctctgta
    15961 tcagcagcat tcgtatttgg agaccactta ggatttacgg caggatttaa ttctaatatg
    16021 ataacaccaa tgatagttgc taaattagtt ggtggtataa cagcagtatt gttagctatg
    16081 gttatcgcaa ataagacact aaagaaggag aatgtataag atggatatat caaatataga
    16141 taaaaattta attgaaacat tagtaagaca aataatagaa gaaaaaataa gtggaactaa
    16201 agacacagta gattttgtta gaaataaaga cattagtgga ataacttcta taaagttacc
    16261 aactgtaaaa gttagtgaat ctgatagatt agatacaggg aatccaagtg atgtagttta
    16321 cacaaaagat ttatttacat tagaggaaag cccaagatta ggttgtggta tgatggaaat
    16381 gaaagaaaca acttttgatt ggactctaaa ttatgatgaa atagattatg taatagatgg
    16441 aactttagat ataataatag atggaagaaa ggtttctgct tcttcaggtg aattaatatt
    16501 cataccaaaa ggaagtaaga tacaattttc tgtacctgat tatgctagat ttatatatgt
    16561 aacatatccg gcagattggg catctcaaaa ttaataaaaa tcaagttaag ttaataatca
    16621 aataaataat ttaaaataca aactcttaaa taagcacgca tatttaaaaa agctatgaat
    16681 taaaattcat agcttttttt ataaagaatg ttatatttta gacgtatttt ttctatattt
    16741 actgggagat atattatatt ttttattaaa taatctaata aaatgct
//
LOCUS       DAEPKC010000088        16670 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.088, whole genome shotgun sequence.
ACCESSION   DAEPKC010000088 DAEPKC010000000
VERSION     DAEPKC010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16670)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16670)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16670
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.088"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..369
                     /gene="tuf"
                     /locus_tag="KR294_002882"
     CDS             <1..369
                     /gene="tuf"
                     /locus_tag="KR294_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887863.1"
                     /note="EF-Tu; promotes GTP-dependent binding of
                     aminoacyl-tRNA to the A-site of ribosomes during protein
                     biosynthesis; when the tRNA anticodon matches the mRNA
                     codon, GTP hydrolysis results; the inactive EF-Tu-GDP
                     leaves the ribosome and release of GDP is promoted by
                     elongation factor Ts; many prokaryotes have two copies of
                     the gene encoding EF-Tu; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HBH0240945.1"
                     /translation="DNIGALLRGVQRNEIERGQVLAKTGSVKAHTKFTAEVYVLKKEE
                     GGRHTPFFDGYRPQFYFRTTDVTGACKLPEGIEMVMPGDNVTMEVDLINSIVVEEGLR
                     FSIREGGRTVASGVVATIIE"
     gene            619..768
                     /gene="rpmG"
                     /locus_tag="KR294_002883"
     CDS             619..768
                     /gene="rpmG"
                     /locus_tag="KR294_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004402360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HBH0240946.1"
                     /translation="MRVKVTLACTECKQRNYNTTKNKKNNPDRIELQKYCRFCKKHTT
                     HKETK"
     gene            794..1015
                     /gene="secE"
                     /locus_tag="KR294_002884"
     CDS             794..1015
                     /gene="secE"
                     /locus_tag="KR294_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HBH0240947.1"
                     /translation="MAAQKNDGAKTKKRFSLFGYLKETKQELKRVTWPTKKELFKNTS
                     IVLTVVISCTILVWGIDTILSGALALLLK"
     gene            1035..1577
                     /gene="nusG"
                     /locus_tag="KR294_002885"
     CDS             1035..1577
                     /gene="nusG"
                     /locus_tag="KR294_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination factor
                     NusG"
                     /protein_id="HBH0240948.1"
                     /translation="MSELQEASWYVVHTYSGHENKVKATIEKAVKTRGMEDCIRQVVV
                     PTEEVVETTKTGKEKTRQRKVYPSYVLVKMIITDESWYVVRNTKGVTGFVGPGSKPVP
                     LSEDEVKAMGIDTTDPKVVNSDIDFEIGDTVKVSQGPFSGQIGNIEEIDLENREVKVC
                     INAFGKRTLFVIELEGIEKI"
     gene            1616..2041
                     /gene="rplK"
                     /locus_tag="KR294_002886"
     CDS             1616..2041
                     /gene="rplK"
                     /locus_tag="KR294_002886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012158357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HBH0240949.1"
                     /translation="MAKKVIGQIKLQIPAGKATPAPPVGPALGQHGVNIMGFTKEFNA
                     KTADQAGMIIPVVITVYQDRSFSFITKTPPAAVLIKKALNLKSGSGEPNKKKVAKMTS
                     AQVREIAELKMPDLNAASVEAAMSMIAGTARSMGVVIED"
     gene            2112..2810
                     /gene="rplA"
                     /locus_tag="KR294_002887"
     CDS             2112..2810
                     /gene="rplA"
                     /locus_tag="KR294_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HBH0240950.1"
                     /translation="MAKKGKRYAGALQKVDRTKFYDASEALTLVSDIAGAKFDETVEA
                     HIKLGVDSRHADQQVRGAVVLPHGTGKTKRVLVFAKGEKAKEAEQAGADFVGAEELVQ
                     KIQGENWFDFDIVVATPDMMGVVGRLGRVLGPKGLMPNPKSGTVTFDVAKAIDEIKAG
                     KVEYRLDKTNIIHVPVGKVSFGGEKLTENFTALMDAIIKAKPAAAKGQYLRSITVASS
                     MGPGVKINPARTAE"
     misc_feature    2862..2990
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            3033..3539
                     /locus_tag="KR294_002888"
     CDS             3033..3539
                     /locus_tag="KR294_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HBH0240951.1"
                     /translation="MRKAIEIKSEVVSEIVEKLQKSSAAVVVDYKGLTVEEVTELRKQ
                     MREAGVDYKVYKNTLVRRAAKEVGIEQFNDELLVGTNAIAFGYDDPVAPARILKGFMD
                     SHPKMKLKMGIVEGAFYDESKIVEMANIPSREVLIAKLLGSLKAPVSNFAYLIDAIAK
                     KAEGQEEA"
     gene            3597..3962
                     /gene="rplL"
                     /locus_tag="KR294_002889"
     CDS             3597..3962
                     /gene="rplL"
                     /locus_tag="KR294_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000159736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HBH0240952.1"
                     /translation="MTIEQILEAIENMKVLELNELVKAAEEKFGVSASAPVMVAGAAA
                     GGPAAEEKTEFDVVLTDVGSSKVGVIKAVREITGLGLKEAKEVVDNAPKTVKEGASKE
                     EADQIKEKLEAAGAKVEVK"
     gene            4354..5142
                     /locus_tag="KR294_002890"
     CDS             4354..5142
                     /locus_tag="KR294_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBH0240953.1"
                     /translation="MEKLQGKIAVVTAATKGIGLASAEILAKNGATVYLAARSEELAN
                     EVINKISAEGGCAKFVYFNAREEETFTSMIEEVVKKEGKIDILVNNFGSTNPSLDKDL
                     VTGDTDNFFDTVNTNLKSVYLPCKAAIPHMIKNGKGSIVNISSIGSVLPDLSRIAYCV
                     SKAAINSLTQNIATQYAKDNVRCNAVLPGLIATKAALDNMSPEFIKEFLKHVPLNRIG
                     EPDDIAKAVLFYASDDSSFITGDLLEVAGGFGLPTPQFADNILG"
     gene            5613..9329
                     /locus_tag="KR294_002891"
     CDS             5613..9329
                     /locus_tag="KR294_002891"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HBH0240954.1"
                     /translation="MPHPVTIGKRTRMSFSKIKEIADVPNLIEIQVDSYEWFLKEGLK
                     EVFDDISPIEDYTGNLILEFVDYSLDDKPKYDIEECKERDATYCAPLKVKVRLINKET
                     GEIKEQEVFMGDFPLMTERGTFVINGAERVIVSQLVRSPGVYYAEERDKTGKRLISST
                     VIPNRGAWLEYETDSNDVISVRVDRTRKQPVTVLLRALGIGTDAEIIDLLGEDERLSA
                     TLEKDNTKTVEEGLVEIYKKLRPGEPPTVESASSLLNALFFDPKRYDLAKVGRYKFNK
                     KLALCYRIMNKISAEDIINPETGEVFVKAGEKISYDLAKAIQNAGINVVNLLMDDDKK
                     VRVIGNNFVDIKSHIDFDIDDLNIKEKVHYPTLKEILDGYSDEEEIKEAIKSRIKELI
                     PKHILLDDIIASISYEFNIFYNIGNIDDIDHLGNRRIRSVGELLQNQVRIGLSRMERV
                     IKERMTVQDMEAITPQALVNIRPVSAAIKEFFGSSQLSQFMDQTNPLSELTHKRRLSA
                     LGPGGLSRERAGFEVRDVHHSHYGRMCPIETPEGPNIGLINSLGTYAKINEFGFIESP
                     YRKFDKETSTVTDEIHYLTADEEDLFVRAQANEPLTEDGKFVNHRVVCRTVNGAVEMV
                     PESRVDYMDISPKQVVSVATAMIPFLENDDANRALMGANMQRQAVPLVRREAPIIGTG
                     IEYRAAKDSGAVVVARNSGIAERVTADEIIIKREDGNRDRYNLLKFKRSNSGTCINQT
                     PIINKGDQIVKGDVIADGPATDLGEVALGRNCLIAFMTWEGYNYEDAILINERLVKED
                     RLSTIHIEEYECEARDTKLGPEEITRDIPNVGDSAIKNLDDRGIIRIGAEVDSGDILV
                     GKVTPKGETELTAEERLLRAIFGEKAREVRDTSLKVPHGESGIIVDVKVFTRENGDDL
                     SPGVNELVRCYIAKKRKIKVGDKMAGRHGNKGVISRVLPEEDMPFMENGTPLDIILNP
                     QGIPSRMNIGQVLEVHLGLAAKTLGWYVATSVFDGANEYDIMDALEEAGYPRDGKLTL
                     YDGRTGESFDNRITVGYMYYLKLHHLVDEKLHARSTGPYSLVTQQPLGGKAQFGGQRF
                     GEMEVWALEAYGAAHILQEILTVKSDDVVGRVRTYEAIVKGENIPEPGIPESFKVLIK
                     ELQSLCLDVKVLTDEDQEIEVRESVDEDDTIGEFELDVVNHMGEVEESNIIEEIEDDF
                     AENAEDEDIENLEEFTEDDLFEEEIDFDSDDFDM"
     gene            9371..12856
                     /gene="rpoC"
                     /locus_tag="KR294_002892"
     CDS             9371..12856
                     /gene="rpoC"
                     /locus_tag="KR294_002892"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HBH0240955.1"
                     /translation="MFELNNFESIKIALASPEKIRQWSRGEVKKPETINYRTLKPEKD
                     GLFCERIFGPQKDWECHCGKYRRVRYKGVVCDRCGVEVTKSKVRRERMGHIELAAPMS
                     HIWYFKGIPSRMGLLLDMSPRSLEKILYFASYVVVDPGETGLNEKQLLTEKEYRTALE
                     KYGYTFTVGMGAEAVKTLLQNIDLEQQSKDLRAELKDSTGQKKVRTIRRLEVVEAFKK
                     SGNKPEWMILDAIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRLLELGA
                     PDIIVRNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSDMLKGKQGRFRQNLLGK
                     RVDYSGRSVIVVGPELKFYQCGLPKKMALELFKPFVMDKLVKEGYAHNIKSAKSIVEK
                     VKPEVWDVLEDVIKSHPVLLNRAPTLHRLGIQAFEPILVEGKAIKLHPLVCTAYNADF
                     DGDQMAVHVPLSVEAQAEARFLMLSVNNILAPKDGSPITTPSQDMVLGCYYLTIEAQD
                     GAKGTGMVFKDFNELLLAYYNKSVHLHALVKLKVTLEDGRSSLVESTVGRFIFNENIP
                     QDLGFVDRKENPFALEVDFLADKKSLGKIIDKCFRKHGNTETAELLDYIKALGFKYST
                     LGGITVAVDDMSVPEEKKVFIAEAEAKVDKYEKAYRRGLISDEERYEKVIETWTETTD
                     KVTDALMGGLDRLNNIYIMAHSGARGSKNQIRQLAGMRGLMANASGKTVEIPVKSNFR
                     EGLSVLEYFTSSHGARKGLADTAIRTAESGYLTRRLVDVSQDVIVREIDCGTEDTTEI
                     YAIKEGNEVIEEIYDRIVGRYTIDPILNPETGEVIVEADSMIQEDEAETIVALGIEKI
                     RIRTVLNCKTNHGVCSKCYGRNLATGKEVNIGEAVGIIAAQSIGEPGTQLTMRTFHTG
                     GVAGADITQGLPRVEELFEARKPKGLAVITEVSGRVEIDETGKRKEVNVIPEEGETQT
                     YVIPYGSRLKVKQGQMLEAGDPLTQGFINPHDIVRVNGVKGVQEYIVKEVQRVYRLQG
                     VDVNDKHIEVIVRQMLSKVKVEDPGDTDLLPGGYEDVLTFNECNKDAIDKGLRPAVAK
                     RVLLGITKASLATDSFLSAASFQETTRVLTEAAIKGKEDHLIGLKENVILGKLIPAGT
                     GMKKYRNIAVEKIED"
     gene            13145..13567
                     /gene="rpsL"
                     /locus_tag="KR294_002893"
     CDS             13145..13567
                     /gene="rpsL"
                     /locus_tag="KR294_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HBH0240956.1"
                     /translation="MPTINQLVRKSRKALEKKSTAPALQKGYNSLNKKVTDASAPQKR
                     GVCTSVKTVTPKKPNSALRKVARVRLTNGIEVSAYIPGEGHNLQEHSVVLIRGGRVKD
                     LPGVRYHILRGTLDTAGVDKRRQSRSKYGAKRPKEAKK"
     gene            13691..14161
                     /gene="rpsG"
                     /locus_tag="KR294_002894"
     CDS             13691..14161
                     /gene="rpsG"
                     /locus_tag="KR294_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001137493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HBH0240957.1"
                     /translation="MPRKGNIPKREVLPDPMYGSKVVTKLINNLMVDGKKGKSQRIVY
                     DAFAIVAEKTGEEALEVFNKAMDNIMPVLEVKARRVGGANYQVPIEVRPERRQTLGLR
                     WLVKYTRARGEKGMVEKLAKEIMDAANNTGASVKKKEDTHKMAEANKAFAHYRW"
     gene            14210..16276
                     /gene="fusA"
                     /locus_tag="KR294_002895"
     CDS             14210..16276
                     /gene="fusA"
                     /locus_tag="KR294_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HBH0240958.1"
                     /translation="MARKFPLERTRNIGIMAHIDAGKTTTTERILFYTGQTHKIGETH
                     EGASQMDWMEQEKERGITITSAATTASWKDHRINIIDTPGHVDFTVEVERSLRVLDGS
                     VAVFCAKGGVEPQSENVWRQAETYGVPRIAFVNKMDILGADFYNVVSMMKSRLNSNAV
                     PMQLPIGKEDSFIGIIDLLKMDAVIYKDDLGVEMEETDIPEDMKELAAEWREKLVESV
                     AETDEELMMKYLEGEELTIDELKVAIRKATIACEMNPVFCGTAYRNKGVQLVIDAVLD
                     YLPAPTDIPAIKGILADGEEAERHSSDEEPFSALAFKIMTDPFVGKLAFFRVYSGTLE
                     SGSYVLNATKNKRERIGRILQMHANTREEITKVYAGDIAAAVGLKDTTTGDTLCDPAN
                     PIILESMEFPEPVISVAIEPSSKAAQEKMGIALQKLAEEDPTFTVKTDQETGQTIISG
                     MGELHLEIIVDRLLREFKVEAKVGAPQVAYRETITQPVDVEYKYSKQSGGRGQYGHVK
                     IRVAPQEPGEGYKFTNKTVGGSVPKEYVGPVDMGIQGAMQSGIVAGYPVVDVAVELYD
                     GSYHEVDSSEMAFKMAGSMAFKDAMKKGNAVLLEPYFKVEVVTPEDYMGDVMGDLNSR
                     RGLIQGMEARSGAQVINAFVPLSEMFGYSTDLRSSTQGRATYTMIFDHYEQVPASVAK
                     KIAEGK"
     gene            16369..>16670
                     /gene="tuf"
                     /locus_tag="KR294_002896"
     CDS             16369..>16670
                     /gene="tuf"
                     /locus_tag="KR294_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887863.1"
                     /note="EF-Tu; promotes GTP-dependent binding of
                     aminoacyl-tRNA to the A-site of ribosomes during protein
                     biosynthesis; when the tRNA anticodon matches the mRNA
                     codon, GTP hydrolysis results; the inactive EF-Tu-GDP
                     leaves the ribosome and release of GDP is promoted by
                     elongation factor Ts; many prokaryotes have two copies of
                     the gene encoding EF-Tu; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HBH0240959.1"
                     /translation="MAKAKYERTKPHVNIGTIGHVDHGKTTLTAAITKTLYDRYQLGE
                     AVDFANIDKAPEERERGITISTAHVEYETPNRHYAHVDCPGHADYVKNMITGAAQM"
BASE COUNT         6554 a         2091 c         3403 g         4622 t
ORIGIN      
        1 gataatatag gagcattatt aagaggagta caaagaaacg agatagaaag aggacaagta
       61 ctagcaaaga ctggatcagt aaaggcacac acaaagttta cagcagaagt atatgtactt
      121 aaaaaagaag agggtggaag acatacacca ttctttgatg gatatagacc acaattctat
      181 ttcagaacaa cagacgtaac aggagcttgt aagttaccag aaggaataga gatggtaatg
      241 cctggagata acgtaacaat ggaagtagac ttaataaact caatagttgt agaagaggga
      301 ttaagattct caataagaga aggtggaaga acagtagctt caggagttgt tgctacaata
      361 atagagtaat tctttactaa actgatggat taaaaggaat aacaaaaaga ggggttatgc
      421 tcctcttttt ttaacataga aatacaaaaa cattgacaca gcataggatt ttgtgataac
      481 ttatacaagg taatgattat aggaagttaa taatatcttg aatactgtag atttttaata
      541 aatacatatt ttaaagatat tatattcaca tatattaaca atatatatta ttgtattaca
      601 aagttggagg tgtatcagat gagagttaaa gtaactttag catgtacaga gtgtaagcaa
      661 agaaactaca acactactaa gaataagaaa aataatccag acagaataga attacaaaaa
      721 tattgtagat tctgtaaaaa gcatacaact cataaagaaa caaaatagtt ttttataagg
      781 atgtgagtat ggaatggctg cccaaaaaaa tgacggtgca aaaactaaaa aaaggtttag
      841 tttgtttgga tacttaaaag aaactaaaca agaattaaaa agagttacat ggccgacaaa
      901 aaaggaactg tttaaaaaca caagtatagt tttaactgta gttatttcat gcactatatt
      961 agtatggggt atagacacta tattatctgg tgcactagcg ttattactaa aatagacgaa
     1021 aagaggtaag ttaaatgtca gaattacaag aagcaagttg gtatgtagtt catacctatt
     1081 cgggacatga aaataaagtt aaagctacaa ttgagaaagc agttaaaaca agaggtatgg
     1141 aagactgcat aagacaagta gttgttccaa cagaagaagt agtggaaact actaaaactg
     1201 gaaaagaaaa aactagacaa cgtaaagttt atccaagtta tgttttggtt aaaatgataa
     1261 taactgatga atcttggtat gtagtaagaa atactaaggg agttacaggt ttcgttggac
     1321 ctggttcaaa accagtgcca ttaagtgaag acgaagtcaa agctatgggg atagacacaa
     1381 cagaccctaa agtagtaaat agcgatattg attttgaaat aggagataca gtaaaagtat
     1441 ctcaaggacc atttagtgga caaataggta acatagaaga aattgactta gaaaatagag
     1501 aagtcaaagt atgcataaat gcatttggta aaaggactct atttgtaata gagcttgaag
     1561 gtatagaaaa aatctaatac tatattatag aaaaatctga ggaggtgcgc tcaaaatggc
     1621 taaaaaagtt ataggtcaaa taaaattaca aatacctgca ggaaaggcta ctccagcgcc
     1681 accagttgga ccagcattag gacaacatgg tgttaatata atgggattca caaaagaatt
     1741 taatgctaaa actgcagatc aagctggaat gataatacca gttgttataa ctgtatatca
     1801 agatagatca ttcagtttta taacaaaaac tccaccagct gcagttttaa ttaaaaaagc
     1861 attaaactta aaatcaggtt ctggagaacc aaacaagaaa aaagttgcta aaatgacttc
     1921 agctcaagta agagaaatag ctgaattaaa gatgcctgac ttaaatgctg catcagtaga
     1981 agctgctatg agtatgatag ctggtactgc tagaagcatg ggtgttgtaa tcgaagacta
     2041 gttaaaagat acactttttt ttataaagtg ggaggctaga agccgaaatt aaccacgagg
     2101 aggaaaataa aatggctaaa aaaggtaaaa gatatgcagg tgcattacaa aaagtagata
     2161 gaactaaatt ttatgatgca tcagaagcat taacattagt ttcagatata gctggagcta
     2221 aatttgatga gacagtagaa gcacacatta aattaggtgt tgactcaaga catgctgacc
     2281 aacaagtaag aggtgcagtt gtattacctc atggaactgg taaaacaaaa agagttttag
     2341 tttttgctaa aggtgaaaaa gctaaagaag ctgaacaagc tggtgctgac tttgtaggag
     2401 ctgaagaatt agttcaaaaa atacaaggtg aaaactggtt tgactttgat atagtagttg
     2461 ctactccaga tatgatgggt gtagtaggta gattaggtag agtattagga cctaaaggtt
     2521 taatgccaaa ccctaaatca ggaacagtta catttgatgt agctaaagct atagatgaaa
     2581 taaaagctgg taaagttgaa tacagattag acaaaactaa cataatacac gttccagtag
     2641 gaaaagtatc atttggtgga gaaaaattaa ctgaaaactt tactgcatta atggatgcta
     2701 taataaaagc taaaccagct gctgctaaag gacaatattt aagaagtata acagtagctt
     2761 cttcaatggg acctggagtt aaaataaacc cagcaagaac agctgaataa taaaactgtt
     2821 gacacaggtt gacaaaaatg ttattatatc acttgtcaat gtaaaaaaga atagatttgc
     2881 cgtagatagt gggtgcgaaa gcttaatatc ccgccgaggt tttagataaa ttgagattac
     2941 taaagctttt gatgtctact tttggcaaca aaagcttttt ataatgttgc ggtaaatact
     3001 aagcctattt ggtgaaggag gtgcacatct atatgagaaa agctatagaa attaaatcag
     3061 aagttgtttc tgagatagtt gaaaagttac aaaaatcttc tgctgctgtt gttgtagatt
     3121 acaaaggatt aacagttgaa gaagtaactg agttaagaaa acaaatgaga gaagctggtg
     3181 tagattacaa agtatacaaa aatactttag ttagaagagc agctaaagaa gttggtatag
     3241 agcaatttaa tgatgaatta ttagttggaa ctaatgccat agcatttgga tatgatgatc
     3301 cagttgctcc agctagaata ttaaaaggat tcatggattc tcatccaaaa atgaaattaa
     3361 agatgggtat tgtggaaggt gcattctatg atgaatctaa gattgttgaa atggctaaca
     3421 taccatcaag agaagttctt atcgctaaat tacttggtag cttaaaagct ccagtatcaa
     3481 acttcgcata cttaatagat gcaatagcga aaaaggcaga aggtcaagaa gaagcttaat
     3541 tgcttaacta aaaaattata aatattaatt tgaaataaaa ttcggaggtg ctaaaaatga
     3601 caatagaaca aatattagaa gctatagaaa atatgaaagt tttagaatta aatgaattag
     3661 ttaaagctgc tgaagaaaaa ttcggtgtat cagcttcagc tccagtaatg gtagctggtg
     3721 cagctgctgg tggaccagct gctgaagaaa aaactgagtt tgatgtagta ttaactgacg
     3781 ttggttcttc aaaagttgga gttataaaag cagttagaga aataacagga ttaggattaa
     3841 aagaagctaa agaagtagtt gacaatgctc ctaagacagt taaagaagga gcttctaaag
     3901 aagaagctga tcaaataaaa gagaaattag aagctgctgg agctaaagta gaagttaagt
     3961 agtttcttta aaaagatacc cattgggtat ctttttttat ttataaaaaa ctataaagaa
     4021 agtatttgga attataaaga aagtattttt ataaaataaa aaaaatttat ataatagtac
     4081 taaattaagg gtatcatata tggtgtaatg gtattttaat ttaacattat tatcaaatta
     4141 aaatataaac aattgttgta atgtctatat ataaagtata taattaaact aaaatgtaaa
     4201 attttacatt ttagtttaaa aaaatacacg aatgttttat aaataaaatg taataaataa
     4261 ttaattaaca aatataaatt ttaaaataag ttagatattt agaaaaatcg aaatttgtag
     4321 gatttaaagg acatattcaa ggaggagtta ataatggaaa aattacaagg aaaaattgca
     4381 gtagttactg cagcaacaaa aggtattgga ttagcatcag cagagatatt agcaaaaaat
     4441 ggagcaactg tgtacttagc agctcgttca gaagaattag ctaatgaagt tataaataaa
     4501 ataagtgcag aaggtggttg tgctaagttt gtttacttta atgctcgtga agaagagacc
     4561 tttacctcaa tgatagaaga ggtagttaaa aaagaaggta agatagatat acttgtaaac
     4621 aattttggtt caacaaaccc ttctcttgac aaagaccttg taactgggga tacagataat
     4681 ttctttgaca cagtaaatac taatttaaaa agtgtgtatt taccatgtaa agcagcaatt
     4741 cctcatatga taaagaatgg aaaaggaagt atagtaaata tatcaagtat aggttcagta
     4801 ttacctgatt tatctagaat agcttactgt gtatcaaaag cagcaatcaa ctcattaact
     4861 caaaatatag ctacacaata tgctaaagac aatgttagat gtaatgctgt acttccaggg
     4921 cttattgcaa ctaaagcagc attagacaat atgtctccag agttcataaa agaattttta
     4981 aagcatgttc ctttaaatcg tataggggaa ccagatgata tagcaaaagc tgttctattc
     5041 tatgctagtg atgactcatc atttataaca ggggatttac ttgaagttgc aggaggattt
     5101 ggtttaccta ctccacaatt tgcagataat atattaggat aattaaatta ctaatatgca
     5161 atgaaagctt atgcattagt tatagtagaa atgatatttt tataaaggcc atagatataa
     5221 tttatattgg aaaggtttga ggttcaaaat tccaagttaa atttatttat ggtctttatt
     5281 ttgtatattt taataaattg tatatatttg tataaatgta attatttaca atcattttaa
     5341 tatggaatta taattaaata ggggggatgg tacttgtata aaatttttta tagaaaatta
     5401 gacctataaa tgaaaaatat ggattttata ttggaaaatt gtacataata cataatatat
     5461 gcttaaaata atttacaaaa aatcaaaaat aatgcatagt ttacatataa gataaaaaat
     5521 atattgaaaa atacttgaca ttatgctaaa attattagat gcgttagaat gaactattgt
     5581 tttattttta attattgaga ggtgaaaagt gaatgccaca tcctgtcacg ataggtaaaa
     5641 gaactagaat gagcttttct aaaattaagg aaatagctga tgtgccaaat cttatagaaa
     5701 ttcaagtaga ttcctatgag tggtttttaa aagaaggttt aaaagaagtg tttgatgata
     5761 tttcaccaat agaagattat actggtaatc ttatattgga atttgtcgac tattctctag
     5821 atgataaacc aaagtacgat atagaagagt gtaaagagag agatgctaca tattgtgcac
     5881 ctctaaaggt taaggtaaga cttataaata aagaaacagg tgagataaaa gaacaagaag
     5941 tgtttatggg tgacttccct ttaatgacag aaagaggaac tttcgttata aatggagcag
     6001 aaagagttat agtaagtcaa ttagttagat ctcctggtgt ttactatgcg gaagaaagag
     6061 ataaaacagg taagagattg atttcatcta ctgtaattcc taatagagga gcatggttag
     6121 aatatgaaac agattctaat gatgtaatat ctgtaagagt tgatagaaca agaaaacaac
     6181 cagttacagt tttacttaga gctttaggaa taggaacaga tgcagagata attgaccttt
     6241 taggagaaga tgagagatta tctgctacat tagaaaaaga taatactaag acagtagaag
     6301 aaggtcttgt agagatatac aaaaaattaa gaccaggtga acctcctact gtagaaagtg
     6361 catcatcttt attaaatgct ttattctttg acccaaaaag atatgaccta gcaaaagttg
     6421 gtagatataa attcaataag aaacttgctt tatgttacag aataatgaat aaaatttcag
     6481 cagaagacat aataaatcca gaaactggag aagtatttgt aaaagctgga gaaaaaataa
     6541 gctatgattt ggctaaagcc atacaaaatg caggtataaa tgtagtaaat ctactaatgg
     6601 atgatgataa aaaagttaga gttataggaa ataattttgt ggatattaag tctcacattg
     6661 attttgacat agatgattta aacataaaag aaaaagtaca ttatccaact ttaaaagaaa
     6721 ttttagatgg atatagtgat gaagaagaaa taaaagaggc tataaaatca agaattaaag
     6781 aacttatacc aaaacatata ttattagatg atataatagc ttcaataagt tatgagttca
     6841 atatattcta taatatagga aatattgatg atatagatca cctaggaaac agaagaataa
     6901 gatctgtagg tgaattgtta caaaatcaag ttagaattgg tctttcaaga atggaaagag
     6961 ttataaaaga aagaatgacg gttcaagata tggaagctat aacgcctcaa gcgttagtta
     7021 acataagacc agtttcagct gcaataaaag aattttttgg tagttctcag ttatctcagt
     7081 tcatggatca aacaaatcct ctatctgagt taacgcataa gagaagatta tcagcccttg
     7141 ggcctggagg tctttcaaga gaaagagctg gattcgaagt gcgtgacgtt caccattcac
     7201 actatggtag aatgtgtcca atagagactc cagagggacc aaatatcggt cttataaact
     7261 ctctaggaac ttatgcaaaa ataaatgaat ttggatttat agaatcacca tatagaaaat
     7321 ttgataaaga aacatcaaca gttactgatg aaatacatta tttaactgct gacgaagaag
     7381 atttattcgt aagagctcag gcaaatgagc cattaacaga agatggtaaa ttcgtaaacc
     7441 atagagttgt ttgtagaact gtaaatggtg ctgttgaaat ggttcctgaa agtagagtag
     7501 attacatgga tatatctcct aagcaggttg tatctgttgc cactgctatg atacctttct
     7561 tagaaaatga tgatgccaac cgtgccctta tgggagcgaa catgcagcgt caggcagtgc
     7621 ctctagttag aagagaagca ccaattatag gaactggtat agaatacaga gcagcaaaag
     7681 actctggagc agttgttgtt gctagaaatt ctggtatagc agaaagagta acagcagatg
     7741 aaataattat aaaaagagaa gatggaaaca gagatagata taatctactt aagtttaaac
     7801 gttcaaactc aggtacttgt ataaatcaaa cacctataat aaataagggt gaccagatag
     7861 taaaaggtga tgttatagca gatggtccag caactgattt aggagaagtt gcacttggaa
     7921 gaaactgtct tatagcattc atgacttggg aaggttataa ctacgaggat gctatattaa
     7981 taaatgaaag attagttaaa gaagatagat tatcaacaat tcatatagaa gaatatgaat
     8041 gtgaagctag agatacaaaa ctagggccag aggaaataac tagagatata cctaatgttg
     8101 gagatagtgc aattaagaac ttagatgaca gaggtataat aagaataggt gcagaagtag
     8161 actcaggtga tatattagtt ggtaaagtaa ctccaaaagg agaaactgaa cttactgctg
     8221 aggaaagatt acttcgtgca atatttggag aaaaggctag agaagttaga gatacttcac
     8281 ttaaagtgcc tcatggtgaa tctggtataa tagttgatgt aaaagtattt actagagaaa
     8341 atggagatga tttatctcca ggagtaaatg aattagtaag atgctatata gctaaaaaga
     8401 gaaaaataaa agttggagat aaaatggctg gtcgtcatgg taataaaggg gttatctcaa
     8461 gagtattacc tgaagaagat atgccattca tggaaaatgg aacaccacta gacataatac
     8521 ttaacccaca aggtatacca tcacgtatga acattggtca ggttttagaa gttcatttag
     8581 gacttgctgc taagacatta ggatggtatg tagcaacatc agtattcgat ggtgctaatg
     8641 agtatgacat aatggatgct cttgaagaag ctgggtatcc tagagatggt aaattaactt
     8701 tatatgatgg tagaacaggt gagtcttttg acaacagaat aactgttgga tatatgtact
     8761 acttgaaact acatcactta gtagatgaaa aactacatgc aagaagtact ggaccatact
     8821 cattagttac tcaacagcca ctaggtggta aagcacaatt tggtggacaa agatttggag
     8881 agatggaggt ttgggctctg gaagcatatg gagctgctca catacttcaa gaaatactta
     8941 ctgttaagtc tgatgacgtt gtaggtcgtg ttagaacata tgaagctata gttaaaggtg
     9001 aaaatatacc tgaaccagga atcccagaat catttaaggt tcttataaaa gaacttcaaa
     9061 gtttatgctt agatgtaaaa gtattgacag atgaagacca agaaatagaa gtaagagaat
     9121 ctgtggatga agatgataca ataggtgaat ttgagctaga tgttgtaaat catatgggag
     9181 aagttgaaga aagtaatata atagaagaaa ttgaagatga ttttgcagaa aatgcagaag
     9241 atgaggatat agagaattta gaagaattca ctgaagatga tttatttgaa gaagaaatag
     9301 attttgatag tgatgacttt gatatgtaaa tttaattaat gtaaatctca aatagaaggg
     9361 agagaactcc ttgtttgaat taaacaattt cgagtcgata aaaatagcat tggcttctcc
     9421 agaaaaaata agacaatggt ctaggggaga agttaaaaag ccagaaacta taaattaccg
     9481 tactttaaaa ccagaaaaag atggtctttt ctgtgaaaga atatttggac cacaaaaaga
     9541 ctgggagtgc cactgtggta aatatagaag agttagatat aaaggtgtag tttgtgatag
     9601 atgtggagta gaagtaacta aatcaaaagt aagaagagag agaatgggac atatagagct
     9661 agcggctcct atgtctcaca tctggtactt caaaggtata ccaagtagaa tgggactttt
     9721 acttgatatg tcaccaagat cgttagaaaa aatattatac tttgcctcat atgtggtagt
     9781 tgatccagga gagactggat taaatgaaaa acaattgctt acagaaaaag aatacagaac
     9841 tgctcttgaa aagtatggat atacttttac tgtaggaatg ggtgctgaag ctgtaaagac
     9901 attactacaa aatatagatt tagagcaaca aagtaaagac ctaagagcgg agttaaaaga
     9961 tagtacaggg caaaagaaag ttagaacaat aagaagatta gaagttgtag aggcatttaa
    10021 aaagtctgga aataaaccag aatggatgat tttagatgca ataccagtaa taccaccaga
    10081 tttaagacca atggtacaac ttgatggtgg aagatttgcg acttcagacc taaatgattt
    10141 atatagaaga gttataaata gaaacaatag acttaaaaga ttattagagc ttggagctcc
    10201 agatataatt gtaagaaatg aaaaaagaat gcttcaagaa gctgttgatg cattgataga
    10261 taatggtaga agaggtagac ctgtaacagg acctggaaat agaccactta aatctttatc
    10321 agatatgtta aaaggtaagc aaggtcgttt ccgtcaaaac ttacttggta agcgtgttga
    10381 ctactcagga cgttctgtta tagttgttgg accagaactt aaattttatc aatgtggact
    10441 tccaaagaag atggcattag aattattcaa gccatttgtt atggataaat tagttaaaga
    10501 aggttatgca cataatataa aaagtgcgaa atctatagta gaaaaagtta agccagaagt
    10561 ttgggatgtt ttagaagatg ttataaaaag tcatccagtt cttcttaacc gtgcaccgac
    10621 tctacataga ttaggtatac aagcatttga accaatctta gttgaaggta aggctataaa
    10681 actacatcct cttgtatgta cagcttataa tgcagacttt gatggtgacc aaatggcagt
    10741 tcatgtacct ttatcagtag aagcacaagc agaagcaaga ttcttaatgc tttctgtaaa
    10801 taatatactt gctcctaaag atggttcacc tataactact ccatctcagg atatggtttt
    10861 aggttgctat tatctaacaa tagaagccca agatggagct aaaggaacag gtatggtatt
    10921 taaagacttt aatgaactat tacttgctta ttacaataaa tcagttcatc tacatgcatt
    10981 agtgaaactt aaggtaacac ttgaagatgg aagaagttca ttggttgaaa gtactgttgg
    11041 tagatttata tttaatgaaa atatacctca agacttaggt tttgtagata gaaaagaaaa
    11101 tccatttgca cttgaagttg atttcttagc agataaaaaa tctcttggta aaataataga
    11161 taaatgcttt agaaaacacg gaaatacaga aacagctgaa ttactagatt atataaaagc
    11221 tctaggattt aaatattcta cattaggtgg cataacagtt gctgttgatg atatgagtgt
    11281 cccagaagaa aagaaagtat ttatagctga ggcagaagct aaagttgata agtatgaaaa
    11341 agcatacaga agaggtctaa tctctgatga agaaagatat gaaaaagtta tagagacatg
    11401 gacagaaaca actgataaag ttactgatgc tcttatgggt ggactagata gattaaataa
    11461 tatatatata atggcacatt caggagccag aggttctaaa aaccaaatta gacagctggc
    11521 aggtatgcgt ggtcttatgg caaatgcatc tggtaaaaca gttgagatac cagttaaatc
    11581 taatttccgt gaaggtttat cagtactaga atactttaca tcttcacatg gtgccagaaa
    11641 aggtcttgcc gatacagcta tacgtacagc tgaatctgga tatttaacaa gaagacttgt
    11701 tgatgtaagt caagatgtta ttgtaaggga aatagattgt ggaacagaag atactacaga
    11761 gatttatgct ataaaagaag gaaatgaagt tatagaagag atatatgata gaattgtagg
    11821 aagatatact atagacccta tattaaatcc tgaaactgga gaagttatag ttgaggctga
    11881 ttcaatgata caagaagatg aagcagaaac tatagtagct ttaggaattg aaaaaattag
    11941 gataagaaca gttcttaact gtaaaactaa tcatggagtt tgttctaagt gttatggtag
    12001 aaacttggca acaggaaaag aagttaatat aggtgaagca gttggtataa tagcagctca
    12061 atctatcggt gagccgggta ctcagcttac aatgcgtaca ttccatactg gaggagttgc
    12121 aggagctgat ataactcaag gtctaccaag ggttgaagaa ttatttgaag ctagaaaacc
    12181 aaaaggatta gctgtaataa ctgaagtatc tggtagagtt gaaattgatg aaacaggaaa
    12241 gagaaaagaa gtaaatgtaa taccagaaga aggcgagact caaacatatg taattccata
    12301 tggttctaga ttaaaagtta agcaaggtca aatgctagag gctggagacc ctctaacaca
    12361 aggatttata aatcctcatg atatagtaag agtaaatggt gttaagggag ttcaagaata
    12421 tatagttaaa gaagttcaaa gagtgtatag acttcaaggg gttgatgtta atgataagca
    12481 tatagaagtt atagtaagac aaatgctatc taaagtaaaa gttgaagacc caggagatac
    12541 agatttattg ccaggtggat atgaagatgt attaacattc aatgaatgta ataaagatgc
    12601 tatagataaa ggtctaagac cagcagttgc taaaagagtt ttacttggta taactaaagc
    12661 atctcttgca actgattcat tcttatcagc agcttctttc caagaaacaa caagagtatt
    12721 aacagaggca gcaataaaag gtaaagaaga ccacttaata ggacttaaag aaaatgttat
    12781 attaggtaag ttaataccag caggaacagg aatgaagaaa tatagaaata tagctgttga
    12841 aaaaattgaa gattaatagc atatagagta aagaaatctt gacaaccatt atttgtggtg
    12901 ttaaaatagt aaagtgtgtt gtttaaaagt acactaaggg cttgaacaag ttcttagtga
    12961 cttttagatg gcaataaatg agaactaaaa agcatcaagc tagaaaagtg ctaatatcac
    13021 atatttatgt gttatagaca ttaaattgta agtaacgaat gttacaatca gtcagtatga
    13081 atattcatat tgatgtagtt ggcggtcact gataagatcg aaaatttgga aggaggtgca
    13141 gatgatgcca acaattaacc aattagttcg taaaagtaga aaagcgctag agaagaaatc
    13201 tactgctcca gcattacaaa aaggttacaa ctctttaaat aagaaagtaa ctgacgctag
    13261 tgccccacaa aaaagagggg tttgtacttc agtaaaaaca gttactccta agaagcctaa
    13321 ctcagcttta agaaaagttg ccagagttag attaactaat ggtatagaag tttctgctta
    13381 tataccagga gaaggacaca acttacaaga gcatagtgtt gttcttataa gaggaggaag
    13441 agtaaaagac cttccagggg ttagatacca tatactaaga ggtactctag atacagcagg
    13501 tgttgataag agaagacaat caagatctaa atacggtgcg aagagaccta aagaagctaa
    13561 aaagtaaaaa caattaatga ttgattatag ttcggtgctt taaatatata tatatttacg
    13621 gcatcacggc attaaatgat ttatgtcgag tacctatgat ttaagttaaa taattaagga
    13681 gggaagcgaa atgccaagaa aaggtaatat tccaaaaaga gaagttttac cagatcctat
    13741 gtatgggagt aaggtagtta ctaaattaat aaataatcta atggtagacg gaaaaaaagg
    13801 aaagtctcaa agaatagttt atgatgcttt cgcaattgtt gctgaaaaga caggagaaga
    13861 agctttagaa gtatttaata aagcaatgga taatataatg cctgttttag aagtaaaagc
    13921 aagaagagtt ggtggggcaa actaccaagt gccaatcgaa gttagacctg aaagaagaca
    13981 aacattaggt ttaagatggc tagtaaaata tactagagct cgtggagaaa aaggaatggt
    14041 tgaaaagcta gctaaagaga taatggacgc agctaacaac actggagctt cagttaagaa
    14101 aaaagaagat actcataaaa tggcagaagc taataaagca tttgctcatt acagatggta
    14161 ggatatatag atatcttata aaattgagga tatcataagg aggataacca tggctagaaa
    14221 gtttcctttg gaaagaacta ggaatatagg aatcatggct catatagatg caggaaaaac
    14281 tactactaca gaaagaatcc tgttttatac tgggcaaact cataaaatag gagaaactca
    14341 tgaaggagct tctcaaatgg actggatgga gcaagaaaag gaaagaggta taacaataac
    14401 ttctgccgct actactgctt catggaaaga ccatagaata aacataatag atactcctgg
    14461 acacgtggac ttcacagttg aggttgaaag atctctaaga gttcttgacg gttcagttgc
    14521 tgtattctgt gcaaaaggtg gggttgagcc tcaatcagaa aatgtatgga gacaagctga
    14581 aacttatgga gtacctagaa tagcttttgt aaataaaatg gatatattag gtgcagattt
    14641 ctacaatgtt gtaagcatga tgaaatctag attaaattct aatgcagttc ctatgcaatt
    14701 accaataggt aaagaagatt catttatagg tataatagac ttattaaaaa tggatgctgt
    14761 tatatacaaa gacgacctag gggttgaaat ggaagaaaca gatataccag aagatatgaa
    14821 agaattagct gctgagtgga gagaaaaatt agttgaatca gtagctgaaa ctgatgaaga
    14881 attaatgatg aaataccttg aaggtgaaga acttactata gatgaattaa aagttgctat
    14941 aagaaaagct actatagctt gtgaaatgaa cccagttttc tgtggtacag cttatagaaa
    15001 caaaggtgtt cagttagtaa tagatgcagt tttagattac ttaccagcgc caactgatat
    15061 accagctata aaaggtatat tagcagatgg agaagaagct gaaagacatt cttctgatga
    15121 agagccattc tctgcattag cattcaaaat aatgactgac ccattcgttg gaaaactagc
    15181 gttcttcaga gtttattctg gaacattaga atcaggttct tatgttttaa atgcaactaa
    15241 gaataagaga gaaagaattg gtcgtatatt acaaatgcat gctaatacaa gagaagaaat
    15301 aactaaagtg tatgctggag atatagcagc agcagtagga ttaaaagata ctactactgg
    15361 agacacatta tgtgaccctg ctaatccaat aatacttgaa tctatggaat tccctgagcc
    15421 agttatatct gttgctatag aaccaagttc taaagcagct caagaaaaaa tgggtatagc
    15481 tcttcaaaaa ttagctgaag aagacccaac tttcacagtt aagactgacc aagaaacagg
    15541 acaaactata atatctggta tgggtgaatt acacttagag ataatagtag atagattatt
    15601 aagagaattt aaagtagaag ctaaagttgg tgcaccacaa gttgcatata gagagactat
    15661 aactcaacca gttgatgttg aatacaagta ctctaagcaa tcaggtggta gaggacaata
    15721 cggtcacgtt aagattagag ttgctcctca agagccaggt gaaggataca aattcacaaa
    15781 caaaactgtt ggtggatcag taccaaaaga atatgttggt ccagttgaca tgggtataca
    15841 aggagctatg caatctggta tagttgctgg atatccagtt gtagacgttg ctgttgagtt
    15901 atatgatggt tcttaccatg aggttgactc ttctgagatg gcgtttaaga tggctggttc
    15961 aatggcattc aaagatgcta tgaagaaagg taatgcagtt cttttagagc cttacttcaa
    16021 agtagaagtt gttactccag aagattacat gggagatgtt atgggtgact taaactcaag
    16081 aagaggatta atccaaggta tggaagctag aagtggtgca caagttataa atgcattcgt
    16141 tccactttca gaaatgtttg gatactcaac agacctaaga tcttcaactc aaggtcgtgc
    16201 aacttacaca atgatattcg atcactatga gcaagttcca gcttcagttg ctaagaaaat
    16261 agctgaagga aaataattta aaaataatta ataatataaa tataaaaaat aatcagctag
    16321 atgagagata tctctcatct agcacaagat aaagggagga aattcaaaat ggctaaagct
    16381 aaatacgaaa gaacaaaacc tcatgttaat atagggacaa taggacacgt agaccacggt
    16441 aaaactacat taacagcagc aataacaaaa acattatatg acagatatca attaggagaa
    16501 gcagtagatt tcgcaaacat agataaagct ccagaagaaa gagaaagagg aatcacaata
    16561 tcaacagcac acgttgagta tgaaacacca aatagacact atgcacacgt tgactgccca
    16621 gggcatgctg actacgttaa gaacatgata acaggagcag cacaaatgga
//
LOCUS       DAEPKC010000089        16543 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.089, whole genome shotgun sequence.
ACCESSION   DAEPKC010000089 DAEPKC010000000
VERSION     DAEPKC010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16543)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16543)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16543
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.089"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            124..1983
                     /locus_tag="KR294_002897"
     CDS             124..1983
                     /locus_tag="KR294_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBH0240960.1"
                     /translation="MKRFLRRIILVLFILLIFISFISIKLIHNVGDYGKLINYVGIVR
                     GASQRLTKLEMNHQPNDELIEYIDEILQELITGHGDYGLVITDCNEYNEDLLLLEKKW
                     EDLNIEIKKVRMKEQNNQLLSISEEFFSLANDTVFKIENFSKEKSNYLMTLIIIISII
                     GILACIILILQYSKKMVRLEKLNVDLKNIAYKDELTGVNTIEKFKLDANQNICIHKDK
                     KFAVFYIDFENFKYINDIFGYDYGDMILKRYANLMMNDIGKYEIFAREIADRFVALRC
                     YVDKEDLVVRQRDVDNELINITNEIKNKHSITVVSGICCIEDVNEKLSIDGLINRANF
                     AQKTVKNKPGTNYAFYNDSIRKKMIEENTIKSRIHEAIEKREFIVYLQPKVNLHSQKI
                     NCAEALVRWLTPDKGIISPAIFIPVLEKNFFIALVDKYVFEEVCKWIRKRLDENKPFV
                     QISVNVSRIQFYNTKFVETYSNIQNKYRIPKNTIEIEFTESVAFENQKHLLEIIHDLH
                     ENGFTCSLDDFGKGYSSLSVLKDLPFDVLKLDSMFFKASLDKDKEKIVIKNIVHMLKE
                     LNITTVAEGIECKEQVEFLRDIGCDLVQGFVFYKPMPILEFEKILDKEFVYNS"
     gene            complement(2275..2874)
                     /locus_tag="KR294_002898"
     CDS             complement(2275..2874)
                     /locus_tag="KR294_002898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HBH0240961.1"
                     /translation="MAIELKKGQKINLTKKENSDLGEILVNLNWNQKVQKKGFFGSLR
                     SSNIDLDLGCLFEMKNGVKGAVQALGNAFGSLDNPPFAQLDGNDRTGSNTQGENLRIN
                     GNKIKDIKRILIYAFIYEGVANWSEADGIVTIKQKQDSDLVVKLDEHKNGYNMCSIAL
                     IENVNDETFSVEKVVKYFKGHREMDTEFHWGLKWVAGRK"
     gene            complement(2977..3774)
                     /locus_tag="KR294_002899"
     CDS             complement(2977..3774)
                     /locus_tag="KR294_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBH0240962.1"
                     /translation="MKFKKLLCLLLCLVLTLAVVGCSKAKDDKKIVVGATLVPGGELL
                     EELKPLIKEKGYTLEVKNFDDYILPNEALNNGEIDANLFQHEPYLKEAVKAKGYKIMA
                     GKKLYVCPAILYSYKIKSVDEFKKGDTIAISNNPSSCSKNLRYLESIGLLTLPKGDGL
                     VSPKDIIENPKGIQFKELDIAQIPSSLPDVTAAFIDTTYAVPAGLDAKKNGIYTAPIN
                     DEYANLLAFRTEDKDSEKIKVLQDVLTSDKARSLIEEKYKGIVIPTF"
     regulatory      complement(3887..3992)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            complement(4084..5070)
                     /locus_tag="KR294_002900"
     CDS             complement(4084..5070)
                     /locus_tag="KR294_002900"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HBH0240963.1"
                     /translation="MLLIYNEKTNPYFNLAMEEYLLKNFDEDLFILWRNEPSIIVGKN
                     QNTLSEINLEYIKEYSIPVVRRQSGGGAVFHDLGNINFTFIACNNNNFSDFRRFTQPI
                     IDLLKTLDVNAEFSGRNDLLIDGKKFSGNAQYNYKNKVMHHGTLLFSSEINDLSKALK
                     VKPIKFEGKGIKSVKSRVTNISEHLHSKMDILEFKDAIMDYLSKTNTDNTNYCLSEHD
                     IKQIEKLTKSKYETWDWNFGNSPKYTLSNELKYSGGNVEFNLNVDKGIITSIKFFGDF
                     FGKCDVAFVENKLIGIRHEENALRNTLDSIEINDYFLGADTDILVSGILGVK"
     gene            5554..7284
                     /locus_tag="KR294_002901"
     CDS             5554..7284
                     /locus_tag="KR294_002901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC family protein"
                     /protein_id="HBH0240964.1"
                     /translation="MRNKKINIIFLTTIMFIMSTVMVFAEEDIDTIALANAEKFGILT
                     LIPPLVAIILAFITKNVIISLLIGILSGSFIIKASGINVFATFIQAFLDLVDRALVSL
                     ADPWNAGIILQVLAIGGVINLVAKMGGAKAIAEALAKRAKSAKGTQLITWFLGLLVFF
                     DDYANSLIVGPMMRPVADKMKISREKLAFIIDATAAPVAGLAIISTWIGLEVGLIHDA
                     FESISIDVDAFGIFLNTIPFRFYNILILAFIVISALLLKEFGPMRKAEIKSRSRKISI
                     DLDEGVEELDDLAPKNGVKLSVWNAIIPIGTLIIVALASFYYSGYTSIMGGDDKALIQ
                     LFTNSPYSFEAIKEAFSASDASRALFQSALVASLVAIIMAVVKKIFTISEAIDVWIDG
                     MKSLVITGVILILAWSLSSVIKELGTAKFLIHLLSGSLPPFLLPSLIFGLGAIISFAT
                     GTAYGTMGILMPLAIPLAYSLNPDMSYVIVSTSAVLTGAIFGDHCSPISDTTILSSMG
                     AGCNHIDHVNTQMPYAIFTAVITIVFGYIPAGLGLPIYIVLPVAIAAIFVGIQIIGKK
                     VDEAEIELVE"
     gene            7394..7474
                     /locus_tag="KR294_002902"
     tRNA            7394..7474
                     /locus_tag="KR294_002902"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:7428..7430,aa:Leu,seq:tag)
     gene            7809..8324
                     /locus_tag="KR294_002903"
     CDS             7809..8324
                     /locus_tag="KR294_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HXXEE domain-containing protein"
                     /protein_id="HBH0240965.1"
                     /translation="MEKYIWLFPLLFIFHDMEEIIGFGIWLKKNKSMLDKKYPFISKV
                     YENYSTEGMAFAVFEEFILCIIFCILTVITENQYVYLLWLGSFIAYTLHLVIHIGQSI
                     IIRKYIPSLITSIICLPISIWCISKSIYIVDCEMSTTILYSIIGIIIVALNLKFAQSL
                     IGKFTKWMSNI"
     regulatory      8816..8920
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            9130..11604
                     /gene="gcvPA"
                     /locus_tag="KR294_002904"
     CDS             9130..11604
                     /gene="gcvPA"
                     /locus_tag="KR294_002904"
                     /EC_number="1.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminomethyl-transferring glycine dehydrogenase
                     subunit GcvPA"
                     /protein_id="HBH0240966.1"
                     /translation="MNELKRVSLYNIHKELGAKLVEFAGWEMPLEYEGINKEHEKVRK
                     SAGIFDVSHMGEVQIKGAESEKFIQNLVTNDISALKINDIIYTPMCYENGGVVDDLLI
                     YKFGEEDYLLVINAGNIDKDVAWIIKQSEGYNVDIKNISSEVSQLAIQGPKAEEILQK
                     ITDIDLNSIKFYKSIPSTKVCGCPCLVSRTGYTGEDGFEIYCKNKYVEIIWNEVLKVG
                     GEDICPAGLGCRDTLRFEAALPLYGHEINEHISPIEGGLSIFVKTNKESFIGKSILSK
                     EKESGAKRKLVGFEMQGKGMPRNGYDIRIGDKTVGFVTTGCASPTTGKILGMGIIDSE
                     YAKVGNEIGIAIRKKVVPAVIVKKPFYKKQYKKDNIILNKENKFSYIPATSEDKSKML
                     KVVGLNSVDELFSDIPEEVKLKRDLNLEIGKSELEVSKIVKRLSEENLSLEDLTCFLG
                     AGAYDHYIPSIIKHITSRSEFYTAYTPYQAEISQGTLQVVFEFQSMIAEITGMEIANA
                     SMYDGATAAIEACIMAMNQTRKSKIVVSKTIHPETLSILRTYLQYKDCEIVEIDFCNE
                     YGTTDIEKLKASVDKDTACVLIQTPNFFGIIEEMEEIEKITHENKAMLIMSVDPISLG
                     VLKTPGEIGADIVVGEAQSLGNPLNFGGPYVGFLASKSKYTRKMPGRIVGQSLDVEGK
                     IAYVLTLQTREQHVRREKATSNICSNQALNALVASIYIATMGKEGFKEVGMQSMKKAH
                     YTYNKLVQTGKYKPIFKGKFFKEFAVQGNLNIETINDKLLEENILGGYNLEYNYPELK
                     NSTLLCVTEKRSKEEIDKLVGIMEGL"
     gene            11604..13061
                     /gene="gcvPB"
                     /locus_tag="KR294_002905"
     CDS             11604..13061
                     /gene="gcvPB"
                     /locus_tag="KR294_002905"
                     /EC_number="1.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminomethyl-transferring glycine dehydrogenase
                     subunit GcvPB"
                     /protein_id="HBH0240967.1"
                     /translation="MKEYNSLLIDISKKGRKAYSLPKLDIDDIKIENMIDQDMARQSE
                     LNLPEVGELELVRHYTLLSNKNFGVDTGFYPLGSCTMKYNPKINEDMAALPNFTGMHP
                     YQSSDTAQGSLSLMYDLSRRLAEITGMDEVTLQPSAGSHGEFTGLMIIKAYHENRGDH
                     KRTKVIIPDSAHGTNPASAAMANFDVIQIASDKNGAVDINALKEVLNDEVAALMLTNP
                     STLGLFEKNIKEIATLVHEAGGLLYYDGANMNAIMGITRPGDMGFDVVHLNLHKTFST
                     PHGGGGPGAGPVGVKKELVPFLPIPVIERKEDKYVLNYDREKSIGKIKNFYGNFGVLV
                     RAYTYILTMGRDGLKEASEMAVLNANYIKESIKDDYILPIDTLCKHEFVLGGLPRGEA
                     NIKTIDIAKRLLDYGYHPPTMYFPLIINEALMIEPTESESIETLDSFIEAMKSVAKEA
                     KEEPELLKTAPHNTLVKRVDDARAVKKPILTWSQR"
     gene            13484..15841
                     /locus_tag="KR294_002906"
     CDS             13484..15841
                     /locus_tag="KR294_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HBH0240968.1"
                     /translation="MDKVNLERYSCDINVGLNKNQLQSRIDDNLINAFDNGKTKTYKQ
                     IFKDNIFTLFNLINIVLVCLLVSVGSFKNTLFIFIAVINTIIGVIQEIRAKRLLDNLS
                     VIVSNKVSVIREKEKKEIDVQELVLDDIMILKTGNQICADSKVLNGKLEVNESLVTGE
                     SDIIIKNKGDFLYSGSFVVSGEAFVRVENIGKDNYANKIANDAKISKKHNSQLRNSLN
                     AILKIVGIIIIPLGIILFAKQHFGNGDSIATSVVGTVAAVNGMIPEGLTLLTSIALAV
                     GTIKLASHKTLVQELYCVETLARVDTLCLDKTGTITEGKMQVDDIVMLEEVDINEIMG
                     NICNSLKDDNATLNAIRDKYNVLDTYKAKNLIPFSSERKYSGVTFENKGTYLLGAFEF
                     IFKEKNKKLRIEVERYSKKGNRVIVLAHSDSYMEDNNIPEDIKPLAFILILDKIRDEA
                     KETLEFFYNEGVDIKIISGDNPITVSEVARKAGLKTASNFIDATTLKNDSDIYKAVDK
                     YSVFGRVSPQQKKQMILALKKQNHTVAMTGDGVNDVLALKEADCSIAMASGSDVTKNV
                     SNLVLLDSNFASMPKVVMEGRKVINNIQRASSLFLVKTIFSFFLSLLTLFFFSRQYPF
                     VPIQLSLIGAVTVGIPSFFLALEANKSRISGNFLLNILKNALPGALCVTVNVIIVYNI
                     VEYLGYSSSVFSTMCAILTGVCGLLILRQQCLPFNKERLFLIVSMTIAFVIGILFLGG
                     LFSFVALSRELILITMALAILMPIMIKVMLFVLDEILETIVPDLN"
     gene            complement(15927..16244)
                     /locus_tag="KR294_002907"
     CDS             complement(15927..16244)
                     /locus_tag="KR294_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine/purine nucleoside phosphorylase"
                     /protein_id="HBH0240969.1"
                     /translation="MSEFKNVTAVKKANVYFDGKVSSRVIILPNGERKTLGLMLPGEY
                     TFSTREEEIMEMLAGSMDVKLPGSNEFVTYKEGQKFNVPSDSSFDLKVNEVVDYCCSY
                     IAD"
BASE COUNT         6249 a         1919 c         2704 g         5671 t
ORIGIN      
        1 aaacaaggtt tatatattct aattgtatag aaaatttatt gtaaacgcat gtatattatt
       61 agaaaaaata gtttgaaggt attcaataaa cataaaaaac aatatagggg ataaaggtgt
      121 tttatgaaga gatttttgag gagaattatc ttagttttat ttattttgtt gatttttata
      181 agttttattt ctattaaatt aattcataat gttggagatt atggaaaatt gattaattat
      241 gttgggattg ttcgtggagc tagccaacgt ctaactaaac tagagatgaa tcatcaacca
      301 aatgatgaat taatagaata tattgatgaa atcctacagg agttgattac agggcatgga
      361 gattatggtt tagtaatcac tgattgtaat gaatacaatg aggacttact tttattagaa
      421 aaaaagtggg aagatttaaa tattgaaatt aaaaaagtaa gaatgaaaga acagaataac
      481 cagttattaa gtataagtga agagtttttt tctcttgcaa atgatacagt gtttaaaata
      541 gaaaactttt ctaaagaaaa aagtaattac ttaatgactt taataataat tatatctatt
      601 ataggtatat tagcatgtat catattgatt ttacaatata gtaaaaaaat ggttagactg
      661 gaaaaattaa atgtagattt aaaaaatatt gcatataaag atgaactaac aggagtaaat
      721 actatagaaa aatttaaatt ggatgcaaat caaaatattt gtatacataa ggataagaaa
      781 tttgctgtat tctatattga ttttgaaaac tttaaataca ttaatgatat atttggatat
      841 gattatggtg acatgatact gaaaagatat gctaatctta tgatgaatga catagggaaa
      901 tatgaaatat ttgcaagaga aattgcagat agatttgttg cgttaagatg ctatgtagat
      961 aaggaagatt tagtggtaag acaacgagat gtagacaatg aactaattaa tataacaaat
     1021 gaaattaaaa ataaacatag tattactgtt gttagtggaa tttgttgtat tgaagatgta
     1081 aatgaaaaat taagtataga tggtttaata aatagagcaa attttgcaca aaaaactgtt
     1141 aagaataaac caggtactaa ttatgctttt tataatgaca gtattcgtaa aaaaatgatt
     1201 gaagaaaata ctatcaagag tagaatacat gaagctattg aaaaaagaga atttatagtt
     1261 tatttacagc ctaaagttaa tttacatagt caaaaaataa attgtgcaga agctttagtt
     1321 cgttggctta ctccggataa aggtattata tcgccagcaa tatttattcc agtacttgag
     1381 aagaattttt ttattgcctt agtagataag tatgtttttg aggaggtttg taaatggatt
     1441 agaaagaggt tagatgaaaa taaacctttt gttcagatat cagttaatgt ttcaagaata
     1501 caattttata acactaaatt tgtagaaact tattccaata tacaaaataa atacaggata
     1561 cctaaaaata ctatagaaat tgaatttaca gagagtgttg cttttgagaa tcaaaaacat
     1621 cttttggaaa ttatacatga tttgcatgaa aatggattta cttgttcttt agatgatttt
     1681 ggaaaaggtt attcgtcttt aagtgtttta aaagatttac catttgatgt tttaaagctt
     1741 gattctatgt ttttcaaggc tagtttagat aaagataaag agaaaatagt aataaaaaat
     1801 attgtacata tgttaaaaga acttaatatc acaactgttg ctgagggcat tgaatgcaag
     1861 gaacaagttg aatttcttag ggatattggg tgtgatttag ttcagggatt tgtattttat
     1921 aaaccaatgc caatattaga atttgaaaaa atattggata aagagtttgt ttataatagc
     1981 taaaatgtac tttataaaat atgaactaat taagtaaaat tattttgtac tgaataaatt
     2041 tttactttat ttacagaata atgattattt acagaaaagc gcgaaaagtg tattccttta
     2101 agtgtgggat ggatagcaca aatagaggag aaaaaatatt ggccatataa gaatgcataa
     2161 taatataaat atttgaaagg tcagcattat ataaaaatta aaaagaaaat aaataatttt
     2221 tctataaaaa agagactatg agaaaattta ctcatagtct cctaaataat gtatttattt
     2281 tcttcctgca acccatttta atccccaatg aaattcagta tccatttctc tatgaccttt
     2341 gaagtattta actacttttt caacactgaa tgtctcatca tttacatttt ctatcaatgc
     2401 tattgaacac atattatagc catttttatg ttcatcaagt ttgacaacta agtctgaatc
     2461 ttgtttttgt ttgattgtta caattccatc agcttcagac cagttagcta caccttcgta
     2521 tataaaagca taaataagta ttctttttat atcttttatt ttattaccat ttattcttaa
     2581 attttctcct tgtgtattac ttcctgttct gtcatttcca tctaattgag caaaaggtgg
     2641 attgtctaaa ctaccaaagg catttcctaa tgcttgaaca gctcctttta caccattttt
     2701 catctcaaat aggcaaccca aatctaaatc tatattactg cttcttaaag agccaaaaaa
     2761 accctttttt tgtacttttt gattccaatt taaattaact aagatttcac ctaaatcgct
     2821 attttccttt tttgtaaggt ttattttttg tccctttttt aattctatag ccatagtaat
     2881 cttcctccac aaacatagat ttatttaaat ggtagcactt aataagtcaa tattcaacaa
     2941 gattagaata ataatattaa aattatacta aatatactaa aaagtaggaa tcacaatacc
     3001 tttgtatttt tcttcaatta agcttcttgc tttatctgat gtaagaacat cttgtagaac
     3061 tttaatcttt tcactgtctt tatcttcagt tctaaatgct aaaagatttg catactcgtc
     3121 atttatagga gctgtataaa ttccgttttt cttggcatca agaccagcag gtacagcata
     3181 agtagtatct ataaatgcag cagtcacatc tggaagagaa gatggaattt gagcaatatc
     3241 taactctttg aattgtattc cctttggatt ttctattatg tccttaggac taactaatcc
     3301 atccccttta ggtaacgtta aaagtccaat actttcaagg tatctaaggt tcttagaaca
     3361 agaagatggg ttattgctta ttgcaattgt atctcctttt ttaaattcat caacagattt
     3421 tatcttataa gagtaaagta ttgctgggca tacatatagt tttttaccag ccattatttt
     3481 gtaacctttg gccttaacag cttcttttag ataaggttca tgttgaaata gatttgcatc
     3541 aatttcacca ttatttaaag cttcgtttgg aagtatgtaa tcatcaaagt ttttaacttc
     3601 taaagtatat cctttttctt taataagtgg ttttaattct tctaataact ctcctcctgg
     3661 aactaaagta gcaccaacaa caattttttt atcatcttta gctttagaac atccaaccac
     3721 agctaaagtt aatactagac ataataacaa acataataat tttttgaatt tcatataaat
     3781 tccctcctga atataattga ttagttaaaa ataaaatacc attctttatc acactgcaaa
     3841 ataaaaataa gcctgagttt aaactcaggc tttaaaagct aatttagact catctttcag
     3901 tataatactg caggatttag caccaatgta tataaaaata tactggttgc tgggtttcat
     3961 agggccagtc ccttcaccac tctggataag aagtatcaat ttttaattat gttataaata
     4021 ttatcatgat tttttacgtc tgtaaacata attttataaa tattttaaaa tctttaatgt
     4081 attttattta acacctaaaa ttccagaaac tagaatatca gtatcagcac ctaagaaata
     4141 gtcatttatt tcaatagaat ccagagtatt tctcaaagca ttttcttcat gccttatacc
     4201 aataagttta ttttctacaa atgcaacatc acattttcca aaaaaatctc caaaaaattt
     4261 tatactagtt attatgcctt tatcaacatt taaattaaac tcaacatttc caccagaata
     4321 ttttaattca tttgaaagag tatattttgg tgaattacca aaattccaat cccaagtttc
     4381 gtattttgat ttagtaagct tttctatttg ttttatatca tgctcactca aacaataatt
     4441 agtattatca gtatttgttt tagaaagata atccattata gcatctttaa attctaatat
     4501 gtccattttt gaatgtaaat gttcacttat attggttaca cgagatttta cagattttat
     4561 tccttttcct tcaaatttta taggtttaac ctttaatgct tttgagaggt catttatttc
     4621 agatgaaaat aaaagagtac catgatgcat tactttgttt ttgtagttgt attgagcatt
     4681 tccagaaaat ttcttgccat ctataagaag gtcatttctt ccagaaaatt cggcattgac
     4741 atctagtgtt ttaagtaaat ctattatggg ctgagtgaat cttctgaaat cactaaaatt
     4801 attattgtta caagctataa atgtaaaatt tatatttccc aaatcatgaa atacagctcc
     4861 accaccagac tgtctcctaa cgacaggtat agaatattct tttatatatt ctaaatttat
     4921 ttcagaaagt gtgttttggt tttttccaac aattatagaa ggttcattcc tccataaaat
     4981 aaataagtct tcatcaaaat tttttagaag atattcttcc attgctaaat taaaataagg
     5041 gtttgttttt tcattataaa ttaataacat taaagtagtt cctccataga attgataaaa
     5101 tttttattat gaatacaatt aattttataa ttcgacaata atataaaaac tcctttaaat
     5161 tagaaatttt aaaaactacc ttgcaaagtt taaataaata atatatactc aaaatatgtt
     5221 taataaaagt gaatagaagg gtagaggcgc aataatctat cagtactaat aaggagttaa
     5281 gcacagagat ttattaggaa aggagatatt gccgaagttt tataatcgat gctttaagat
     5341 tatattgctg ggggtacata gaaaatatgt acaactgtca caggtttatt tgtggtgagc
     5401 tatcatttaa ggaattatat tatatttatt tttactattg ttgatatatt gtaatgttta
     5461 agccttgagt gtttaccact caaggctttt ttagttttat tgtaacataa taccctgtac
     5521 agttcacaaa attaaaagga gagggagatt tatatgagga acaaaaaaat taatattatt
     5581 tttctgacga caatcatgtt cataatgtca acagtaatgg tttttgcaga agaagatata
     5641 gacactattg cactagccaa tgcagaaaaa tttgggattt taactttaat accaccatta
     5701 gttgctataa tacttgcatt tataactaaa aacgtaataa tttctttact tataggtatt
     5761 ctttctggta gttttataat taaagctagt ggtattaatg tttttgcgac atttatacag
     5821 gcatttttag atttagtaga cagagcttta gtatctttag cagacccttg gaatgcaggg
     5881 ataatactac aggttttggc aattggagga gtaataaatc ttgttgctaa aatgggagga
     5941 gctaaagcta tagctgaagc acttgctaaa agagcaaagt cagcaaaagg gacacagctt
     6001 ataacatggt ttttggggct tttagtattc tttgatgatt atgccaattc actaatagta
     6061 ggtcctatga tgagacctgt tgcagataaa atgaaaatat cgagagaaaa gctagcattt
     6121 ataatagatg ccacagcagc accagttgct ggtttagcta taatatctac atggataggt
     6181 cttgaggttg gtttaataca tgatgctttt gaaagtataa gtatagatgt agatgcattt
     6241 ggtatatttt taaatacaat accatttaga ttttacaata tattaatatt agctttcatt
     6301 gtaatatcag cattattatt aaaagaattt ggtccaatga gaaaagctga gataaaatct
     6361 agaagtagaa aaattagtat agaccttgat gaaggcgtag aagagttgga tgatttagct
     6421 ccaaaaaatg gagtaaaatt gagtgtatgg aatgctataa tcccaatagg aacattgata
     6481 atagttgcat tagcatcatt ttattatagt ggatatacat ctataatggg aggagacgat
     6541 aaggctctga tacaactatt tacaaattct ccatattctt ttgaagcaat aaaagaagca
     6601 tttagtgcat ctgatgcatc tagagcatta ttccagtctg cacttgttgc aagtttagtt
     6661 gctattataa tggctgtagt aaaaaagatt tttacaatat cagaagcaat tgatgtttgg
     6721 atagatggaa tgaaaagttt agtaatcact ggtgtaatat taatacttgc atggtcatta
     6781 agttcagtaa taaaagagtt aggtacagct aaatttttaa tacacctatt atcaggttca
     6841 ctaccaccat tcttattacc aagtttaata tttggtttag gagcaataat atcttttgct
     6901 actggaacag cttatggaac aatgggtata cttatgccac ttgcaattcc attagcatac
     6961 tcattaaatc ctgatatgtc ttatgtaata gtaagtacta gtgcagtttt aacaggtgca
     7021 atatttggag accattgttc tccaatttca gatacaacaa tactttcttc aatgggagct
     7081 ggctgtaatc atatagacca tgttaacact caaatgccat atgctatatt tacagcagta
     7141 atcactattg tatttgggta tataccagct ggacttggat tgccaatata tatagtatta
     7201 ccagtggcaa tagctgctat atttgtaggt attcaaataa ttggtaagaa agttgatgaa
     7261 gcggaaatag aacttgtaga ataaagatat aaataagttt caccttttat tatcactatt
     7321 ttgttagttt ttagataatt ttaaaaagtt attgaaaata atggcgaaat atagtaaaat
     7381 aaaagagtga taagcggatg tggcggaatt ggcagacgca ctagacttag gatctagcgc
     7441 cattggcgtg ggggttcgac tcccttcatc cgcactttac agtacttaat tgtactgaaa
     7501 aaaactgggg ttgctggctt tcggagtggg ctatcccgtt tttatttttt tgtatatata
     7561 atagattggc actttagtat aaggtgcttt ttttataggc aaaaacagta catttatttc
     7621 tgttttatta tcattcatct attagaatat actttagtta agaatgtgtt aataagcagt
     7681 gttcacattc ttgataaaat gtggaataat atgtattttt actaagacgg aaatgaaata
     7741 attaaaccat taaataatat tataagatga tgaataagta gataaatcaa attttgtagg
     7801 aggatattat ggaaaaatat atatggttgt ttccattact ttttattttt catgatatgg
     7861 aagagataat aggttttgga atatggctta aaaaaaataa atcaatgctt gataagaagt
     7921 atccatttat cagtaaagtt tatgaaaatt atagtactga aggcatggca tttgctgtgt
     7981 ttgaagaatt tattttatgc attattttct gtatacttac agttataaca gagaatcagt
     8041 atgtatatct actatggtta ggtagtttta tagcatatac cttacatttg gtaattcata
     8101 tagggcagtc aatcataata agaaaatata taccttcact tattaccagt atcatatgct
     8161 taccaataag catttggtgt ataagtaaga gtatttatat agttgattgt gaaatgagta
     8221 caacaattct gtacagtata attggcatta taattgtagc attgaattta aagtttgcac
     8281 agtcgctgat tggaaaattt acaaagtgga tgtcaaacat ataaatttta gtttattgga
     8341 cagttcaagg aatcagaaat tggaatttta tagtattaat attttatggt attaatataa
     8401 tgtataaaat tttatagcaa tgtatttcat aagtataaag tgactagaat tttaagaaat
     8461 atacaaattc tataaaaact aaataatttc aagtatattt taaaaatctt atttttcaca
     8521 agtttaaaat tgtaaacgat ttcatcaagt ctatgaatat acttttaaca tgttatagta
     8581 aatctcaata taaatttaca tttggttctt tgtgtgttat tttaataata aattaagtga
     8641 aaatgttatt ttacattaat atataatatc tttgcataag agtgaataat ataaaagaga
     8701 aataattgat aataaaaact taacaaaaaa attaatacat aaaaaaaaat aaatataatg
     8761 tgttgacatt taattgaaat attcatacaa taaaattgaa aataaatatt tccaaatgag
     8821 attagcgaga gagtccttta tacgaaaagg cgccgaagaa gaaatttaag aaatgccaat
     8881 ttttagagaa gctttcaggc aaaaatatcg ctaattgatg ggactctgga gagacttaag
     8941 ttaagatact ataagtcacc gaagaagcaa aataatatta aattattaaa tctttcaggt
     9001 atacaaacag ggatatatag gctaggatta ttttccatgc tgatatatct tttttttatg
     9061 aaaaagtaca ggaaataata tcaaagttac ttaaatacag taggtctaat tttctaggga
     9121 gggttatata tgaatgaatt gaaaagagta tctttgtaca atatacacaa agagcttgga
     9181 gcaaaacttg ttgaatttgc tggttgggaa atgcctttag aatatgaggg tataaataaa
     9241 gagcatgaga aggtcagaaa aagtgcaggt atatttgatg tatctcatat gggagaggta
     9301 cagataaagg gagcagagtc agaaaaattt atacaaaacc tagttacaaa tgatataagc
     9361 gcattaaaga taaatgatat tatatataca cctatgtgtt atgaaaatgg tggagtagtt
     9421 gatgatttat taatatataa atttggtgaa gaagattatt tattagtaat aaatgcaggt
     9481 aatatagata aagatgtagc atggataata aaacaaagtg aaggatacaa tgtagatata
     9541 aaaaatatat ctagtgaagt gagtcaatta gcaattcaag gacctaaagc agaagaaatt
     9601 cttcaaaaaa tcacagatat agacttaaac tcaataaaat tttataagtc aattccatca
     9661 acaaaagtat gtggttgtcc ttgtttagtt tcaagaacag gatatactgg ggaagatggg
     9721 tttgagatat actgtaaaaa taaatatgta gaaataattt ggaatgaagt tctaaaggtt
     9781 ggaggagaag atatatgtcc agctggtcta ggttgtaggg atactttgag atttgaagca
     9841 gctctacctc tatatggaca tgaaataaat gaacacatat ctccaattga aggtggttta
     9901 tctatctttg tgaaaacaaa taaagaatca tttattggca aatcaatttt atcaaaagaa
     9961 aaagaaagtg gagctaaaag aaagttagta ggatttgaaa tgcaaggtaa aggaatgcct
    10021 agaaatggat atgatataag gattggtgat aaaacagttg gatttgtaac aacaggatgt
    10081 gcatctccaa cgacaggaaa aattttaggt atgggaatta tagattctga atatgcaaaa
    10141 gtaggaaatg aaataggtat agcaatcaga aaaaaagttg ttcctgctgt gatagttaag
    10201 aaaccttttt ataaaaaaca atataaaaaa gataatatta tattaaacaa agaaaataaa
    10261 ttttcatata tacctgctac aagtgaagat aaatcaaaaa tgttaaaagt agttggatta
    10321 aattcggttg atgaattatt ttcagatata ccagaagaag taaaattaaa aagagattta
    10381 aatttggaaa ttggaaaatc tgaattagag gtaagcaaaa tagtaaaaag attgtcagaa
    10441 gaaaatttaa gtttagaaga cttgacttgt tttcttggtg ctggtgcata tgaccattat
    10501 ataccatcaa ttataaaaca tataacttca agatctgaat tttatacagc atatactcca
    10561 tatcaagctg aaataagtca gggaacttta caagtagttt ttgaatttca atctatgatt
    10621 gcagaaatta caggtatgga aattgcaaat gcatcaatgt atgatggagc aactgctgca
    10681 atagaagcat gtataatggc aatgaatcag actagaaaaa gtaaaatagt agtgtcaaaa
    10741 actattcatc ctgaaacttt gtcaatatta agaacttact tacaatataa agattgtgag
    10801 atagtagaaa ttgacttttg taatgaatat ggcactacag atatagaaaa attaaaagct
    10861 tctgtagaca aagatacagc atgtgttctt atacaaactc ctaatttctt tggaattatt
    10921 gaagaaatgg aagaaataga aaagataact catgaaaata aggctatgtt aattatgagt
    10981 gtagacccaa tatcattagg agttttaaaa acaccaggtg agataggtgc agatattgtt
    11041 gttggagaag ctcaatcact tggaaaccct cttaattttg gaggtcctta tgtaggattt
    11101 ttagctagca aatctaaata tactagaaaa atgccaggaa gaatagttgg gcaaagttta
    11161 gatgtagaag gtaaaattgc atatgtatta actttacaaa ctagagaaca gcatgtaaga
    11221 agagaaaaag caacttctaa tatatgttca aatcaagctt taaatgctct tgtagcttca
    11281 atatatatag ctactatggg taaagaagga tttaaagagg ttggtatgca gtctatgaaa
    11341 aaagcacatt atacttacaa taagcttgta caaactggaa aatataagcc aatatttaaa
    11401 ggtaagtttt tcaaagaatt tgctgtacaa ggaaatctta atatagaaac tataaatgat
    11461 aaactcttag aagaaaatat attaggtggt tataatttag aatacaatta tccagaatta
    11521 aaaaattcaa ctttgctttg tgtgactgag aaaagaagca aagaggaaat agataagtta
    11581 gttggaataa tggagggatt ataatgaaag aatacaatag tttgttgata gatatatcta
    11641 aaaaaggtag gaaagcatac tcacttccaa agttagatat agatgatata aaaatagaaa
    11701 atatgattga ccaagatatg gcaagacaaa gtgagttgaa tttgccagaa gttggtgaat
    11761 tagaattagt tagacattat acattattat caaataaaaa ctttggagtt gatacaggtt
    11821 tttatccttt gggttcttgt actatgaaat ataatcctaa aataaatgaa gatatggcag
    11881 cacttccaaa ctttactgga atgcatccat accaatcttc ggatacagct caaggttctc
    11941 tttctttgat gtatgattta tcaagaagac ttgcagaaat tacaggtatg gatgaagtta
    12001 cactacaacc ttcagcaggt tctcatggtg agtttacagg gcttatgatt ataaaagcat
    12061 atcatgaaaa tagaggtgac cataagagaa ccaaagtgat aattccagat tctgcacatg
    12121 gaacaaatcc agcaagtgca gctatggcaa actttgatgt gattcaaata gcatctgata
    12181 aaaatggagc tgtagacata aatgcattaa aagaggtttt gaatgatgaa gtagcagctc
    12241 ttatgcttac taatccaagt actcttggtt tatttgaaaa aaatataaaa gaaatagcta
    12301 ctcttgtaca tgaagcagga ggacttttgt actatgatgg tgcaaacatg aacgctatta
    12361 tggggataac aagacctgga gatatggggt ttgatgtggt tcatcttaat cttcataaga
    12421 ctttttcaac tcctcatgga ggtggaggtc caggagctgg tcctgttgga gttaaaaaag
    12481 aattagtacc ttttttacca ataccagtaa ttgaaagaaa agaagataag tatgtactaa
    12541 attatgatag agaaaaatct attgggaaaa ttaaaaattt ctatggtaat tttggagttc
    12601 ttgtaagagc ttacacatat atactaacta tgggaaggga tggacttaaa gaggctagtg
    12661 aaatggcagt tttaaatgct aattatataa aggaaagtat aaaagatgat tatattttgc
    12721 caatagatac cttgtgtaag catgagtttg tattaggtgg attgccaaga ggagaggcca
    12781 atataaaaac tatcgatatt gcaaaaagac tactagatta tggataccat cctccaacaa
    12841 tgtactttcc tcttattata aatgaggcac ttatgataga acctacagaa agtgagagta
    12901 tagagacatt agatagtttt atagaagcta tgaaaagtgt tgctaaagag gcaaaggaag
    12961 aaccagaact attgaaaact gctccacata atactttggt caaaagagta gatgatgcaa
    13021 gggcagtaaa gaaacctata ctaacatggt cacaaagata aatagttaaa aagtagagat
    13081 ttaaagtata aagagaatta aatttgtaag aaaaagctat ctaacttaat ctagtttaga
    13141 tagctttttt gtatattagt atgtatggta ttttctatat aaagttttaa attatattag
    13201 tgcttatata gaatattgat atgatgatta tgtatagata ttaataagaa ttgttgaatt
    13261 tatcttgcct taactttatt tactctttta tattaagaaa aacttaacta aaatatagcg
    13321 aaattcataa aaatttagga aatcttaaga attataatat ttaaatcttt agatttatat
    13381 tttattatat aaactataga ataataaaat aaaaaaattg agaattttat aatatatttg
    13441 tagatttgag tataaaaaag tgctaagttg aaaggagtaa aatatggata aggttaattt
    13501 agaaaggtat agttgtgata taaatgttgg tttaaataaa aatcaacttc aaagtagaat
    13561 agatgataat ttaattaatg catttgataa tggaaaaacc aaaacatata aacaaatttt
    13621 taaagacaat atatttacac tttttaatct cataaatatt gttttagtct gtttattagt
    13681 ttcagttggt tcttttaaaa ataccttatt tatatttatt gctgtaatta atactattat
    13741 aggagtaata caagagataa gagctaaaag attattggac aatctatctg ttatagtttc
    13801 aaataaggta tctgtcataa gagaaaaaga gaaaaaagag attgatgtac aagaattagt
    13861 attagatgat attatgattt taaaaacagg taatcaaatt tgtgcagatt caaaagtttt
    13921 aaatggaaaa ttagaggtaa atgagtcttt ggttacaggt gaatctgata ttattataaa
    13981 aaataaaggc gattttttat attctggaag ttttgtagtt tctggagaag cttttgtaag
    14041 agttgaaaat ataggaaaag ataactatgc aaataagata gctaatgatg caaagatttc
    14101 taaaaaacat aattctcaac ttagaaattc attaaatgca atattaaaaa ttgtaggtat
    14161 aataataatt cctttaggaa ttatattgtt tgcaaaacaa cattttggaa atggagattc
    14221 tatagctaca tctgtagtag gtacagtggc agctgtaaat ggtatgatac cagagggatt
    14281 aacattactt acgagcattg ctctagctgt aggaactata aaacttgcta gtcataaaac
    14341 tttagtgcaa gaactgtact gtgtagagac tcttgctaga gttgatacac tatgtcttga
    14401 taagacaggt acaattacag aaggtaaaat gcaagttgat gatatagtaa tgttggaaga
    14461 agtggatatt aatgaaataa tggggaatat atgtaattct ctcaaagatg ataatgcaac
    14521 actaaatgca ataagagata agtataatgt tttagatacg tataaagcta agaatttaat
    14581 accattttct tcagaaagaa aatacagtgg ggttaccttt gaaaataaag gtacatattt
    14641 attaggtgca tttgagttta tatttaagga aaaaaataaa aaacttagga tagaagttga
    14701 aagatattct aaaaaaggaa acagagtaat agttttagct catagtgatt cttatatgga
    14761 agataataat attcctgaag atataaagcc actagctttt atattgatat tggataaaat
    14821 tagagatgaa gctaaggaaa ctttagaatt tttttacaat gaaggtgtag atataaaaat
    14881 tatatctggt gacaatccta taacagtaag tgaggtagct agaaaagcag gtcttaaaac
    14941 agctagtaat tttattgatg caacaacact taaaaatgat agtgatatat acaaagcagt
    15001 tgataaatac agtgtttttg gaagggtaag cccacaacag aaaaaacaaa tgattttagc
    15061 attaaaaaaa caaaatcata cagtagctat gactggagat ggtgtaaatg atgtactagc
    15121 acttaaagaa gcggattgta gcattgccat ggcatctgga agtgatgtta ctaagaatgt
    15181 gtctaattta gtcttattag attcaaactt tgcatcaatg ccaaaggttg ttatggaggg
    15241 aagaaaagta attaataaca ttcaaagagc atcttctttg tttttagtaa agacaatttt
    15301 ttcattcttc ttgtcgttat taacattatt cttcttcagt agacagtatc catttgttcc
    15361 tatacaatta tcactcattg gggctgtaac agtgggtata ccatcattct tcttagctct
    15421 tgaagcaaac aaaagtagaa tttcaggaaa ttttttactc aatatattaa aaaatgcttt
    15481 accaggagca ctatgtgtga cagtaaatgt aattattgtt tacaatatag ttgaatattt
    15541 aggttatagt tcaagtgtat tttccacaat gtgtgctata ttaactggtg tatgtggtct
    15601 tttaatattg agacaacaat gtttgccatt taataaagaa agattatttt taatagtaag
    15661 tatgactatt gcatttgtta ttgggattct atttttaggt ggattattct catttgtagc
    15721 attgagtaga gaattaattc tcataactat ggcattagca atattaatgc caattatgat
    15781 aaaagttatg ttatttgtct tagatgagat attagagaca attgttccag atttaaatta
    15841 attttaaaat gatataaata agagcagttt tagttgaact gctcttttta gatgtgttta
    15901 attttatgta agaatatgta tttttattaa tcagctatat atgagcaaca gtagtcaaca
    15961 acttcattaa cctttaagtc aaaacttgaa tcactaggaa cattaaattt ttgcccttct
    16021 ttataagtta caaactcatt gcttccaggc agttttacat ccatacttcc agcaagcatc
    16081 tccattattt cttcttctct agtagaaaaa gtgtattctc ctggcaacat taatcctaaa
    16141 gtttttcttt ctccattagg cagtattatt actctgctac ttaccttacc atcaaaataa
    16201 acgtttgcct tctttactgc agtaacattc ttaaattcac tcattagata aaacctccaa
    16261 aattatttgt acatatatat tatataaaaa taatgtaaaa aatgctatat atttacaaaa
    16321 aaatttagta tttattaaaa aaattaataa gaataaaaaa gaggtgaaat tgcttaaatt
    16381 gataaaaaat ataaaataaa ttgcaaagta agcaagaaaa gaataagttg aagagttata
    16441 tattataaat attaaaaatt ttagtattaa taaaaaagat attacattaa tatgaaaata
    16501 taggagatta gaagtgtttg attaaaaaat agctacacac act
//
LOCUS       DAEPKC010000090        16293 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.090, whole genome shotgun sequence.
ACCESSION   DAEPKC010000090 DAEPKC010000000
VERSION     DAEPKC010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16293)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16293)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16293
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.090"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            177..827
                     /locus_tag="KR294_002908"
     CDS             177..827
                     /locus_tag="KR294_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic nucleotide-binding domain-containing
                     protein"
                     /protein_id="HBH0240970.1"
                     /translation="MKAEKTSIYPIIKNNLNKISIVEYKKGQRFVASDKDLQEVFFII
                     EGVALVECTTRGGNKFLVDIVPENEFIGKISYIYEHNLKCDIFAKTNIKLFRFEKNVF
                     EEFYLKPDFIALFHRKCTRRIYELYKTRMVRELFSCTEVIAYCISNKQENNVCNIKAI
                     RNFSEIYSISRKSRYHSLLKLTEKEIVKKMGNTYEILNYDELHKLAFEVKEFLEDE"
     gene            complement(967..2343)
                     /locus_tag="KR294_002909"
     CDS             complement(967..2343)
                     /locus_tag="KR294_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBH0240971.1"
                     /translation="MQELFSLKDENKRFYKILLSLCIPIIIQNLISTSVNVIDTIMIS
                     SLGETSVASVGVANQFFFLFNMSLSGITGGAGVFISQFYGKKDVSNIRKVTGLTCVLA
                     IVLSFVFVIPALLTPKPIIHIFSYDSEVVKLCIDYFSIAVFSYPLIAVSTVFSTGSRG
                     VRNPKLGMICSAFALVTNVILNYGFIFGNFGLPALGVKGAALATVIARICELILMITY
                     VYLYKKDYILKFGLKNLKAIDKIFIKSFSSKSFPIFVNDSVWAIGTVLYSVAYARAGT
                     SAIAASQIATSTGNFFIMTAVCIASGASIMLGNELGADHIKRAIEYAKKFSILVFSAG
                     LILGIILILNIPLLLKMFSVSDSLASDITKIFFIMGILMALKSFNTLVIIGILRSGGD
                     TKYALFLELGCMWLASIPLTFIAAFKGAPIFVLVLLTYSEEVVKFIFGVPRALSKKWA
                     INIVKEID"
     gene            complement(2359..4272)
                     /locus_tag="KR294_002910"
     CDS             complement(2359..4272)
                     /locus_tag="KR294_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBH0240972.1"
                     /translation="MIVLSCNNLNKSFGIDSILENISFTVNEGDKIGIIGVNGTGKTT
                     LFKIISGIYGYDSGDIYTSKDCEIGYLEQNTNFYSDNTILEEVLEVFKNLIEMESYLR
                     ELEVKISEESTKTNSPIIEKIMDEYSHKLELFSDLNGYGYKSEAKGVLKGLGFSDNDM
                     DKPISILSGGEKTRVLLGKLLLKKPTLLLLDEPTNHLDSEAIEWLEVFLKQYKGTVML
                     ISHDRYFLDQSVNRIFEVHNKKLKVYNGNYSKFVELSKIEKELELKKFEDQQKEIKKQ
                     EESIERLKAYGREKHLKRARSKEKALDKVDVLDKPEAYRKKARIQFTPSVQSGNDVLQ
                     IRDVSMGYGERILFKDLDLDIYRGEKVALIGANGVGKSTLFKIITNELQPLSGNIKFG
                     TNVHVSYFHQEQKTLNLDNTIIDEIWENNTHLTQTTLRNMLGAFLFVDEEVFKKISTL
                     SGGERARVAILKLILSNANLLLLDEPTNHLDIDSKEVLEEALTNYDGTIFTISHDRYF
                     LNTVVDKILVLDENGITEYLGNYDYYIDKKRQIQEMSIIEEKEEKTRTQIKDEKRKER
                     EQREIEKKNRIKRQNIEKEIEKLEIEIEKLDILLCQEEVYSNPDKAKEVSQEKINLEN
                     NLASLYDEWEEFM"
     gene            4408..5040
                     /locus_tag="KR294_002911"
     CDS             4408..5040
                     /locus_tag="KR294_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HBH0240973.1"
                     /translation="MLGNKNISMAVIRRLPKYHRYLGDLLDRDIQRISSKELSDIIGF
                     TASQIRQDLNNFGGFGQQGYGYNVEALHTEIGKILGLDRPYNAVLVGAGNLGQAIANY
                     AGFRKAGFEIKALFDANPRMIGLKIREFEVLDSDTLEDFIKNNNIDIAVLCIPKNGAQ
                     EVINRVVKAGIKGVWNFAPLDLEVPKGVIVENVNLTESLFTLSYLMKEGK"
     gene            5179..5718
                     /locus_tag="KR294_002912"
     CDS             5179..5718
                     /locus_tag="KR294_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraR/DksA C4-type zinc finger protein"
                     /protein_id="HBH0240974.1"
                     /translation="MVFVEELWKKAIEFHGHECPGLAIGFKAALAAKKYLGCKQSGDE
                     EIVCISENDACGIDGIQVVLSCTMGKGNLLLRMTGKSVYHFFNRENGKSIRIYVKSKP
                     FEMDREGYKRYLLESDFEEIFEITDTKLRLPEKARIFKSLKCEVCGEFASEQYIRIEE
                     GKKVCLDCFDKYERFYEEY"
     gene            complement(5894..6064)
                     /locus_tag="KR294_002913"
     CDS             complement(5894..6064)
                     /locus_tag="KR294_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004619190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBH0240975.1"
                     /translation="MAYKITDACISCGACEAECPVSCISAGDDAYVIDAGSCIDCGSC
                     AGACPVDAPQPE"
     gene            6349..7416
                     /locus_tag="KR294_002914"
     CDS             6349..7416
                     /locus_tag="KR294_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HBH0240976.1"
                     /translation="MKNKLVYICIMSLLLFVVGCSNNPNKESTIKKDSKNNQSQVKEE
                     KREPVKKDITISFAGDVTMGNYKGSSYYGSFDHEFKRQGEDYNYFLKNVKPVFEKDDL
                     TVVNLEGPLTTASNAKEKKFAFKGKPGYVNILKSGSVEAVSIANNHSEDYFEEGMKDT
                     QFILDENKINYFGLGKDAVVDVKGIKVGLLGYNGLSTEYNEKNLKQMEDDIKSLKKKS
                     DVVVVYFHWGIELDYYPDKKQKDFAHYAIDKGADLVMGSHPHVIQGIEKYKNKYIAYS
                     LGNFCFGGNKNPSDTDSYIYQQTFTFSDNKLTSIKEPNIIPTSITSSNSRNNYQPKIL
                     DGSEKDRVLNKLEKISKDLNK"
     gene            7586..9487
                     /gene="cooS"
                     /locus_tag="KR294_002915"
     CDS             7586..9487
                     /gene="cooS"
                     /locus_tag="KR294_002915"
                     /EC_number="1.2.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic carbon-monoxide dehydrogenase
                     catalytic subunit"
                     /protein_id="HBH0240977.1"
                     /translation="MACNTCKMCESADKKLESFVASKDVETAFHRTEDQKVKCGFGLQ
                     GVCCRLCSNGPCRVTPKSPRGICGADADTIVARNFLRAVASGAACYLHVVENTAKNLK
                     NVGITKGVVKGEKTLNQLAEMFGIESDEKYDKCIKVADKVINDLYKSRDDKMELVEKI
                     AYAPRVKKWKELGIMPGGAKSEVFDAIVKSSTNLNSDPVDMLVNCLNLGISTGLYGLT
                     LTNLLNDVMLGEPVIRMAPVGFNVIDPDYINIMITGHQHSTFANFQDRLKDEDVIKLA
                     QSVGAKGFKLVGCTCVGQDLQLRGEHYQEVFAGHAGNNFTSEAVLSTGAIDIVLSEFN
                     CTIPGLEPIADKYKVKMVCLDDVAKKANAECIGLDRSKLDELSNTLIEKALESYKERR
                     GSIEIDIPKDHGFEQSLTGVSEKNLKAFLGDSWKPLINLIAEGKIKGVAAVVGCSNMT
                     AGGHDVNTVELTKELIKKDIIVLSAGCSTGGLENVGLMSPGAEELAGENLKEVCKTLG
                     IPPVLNFGPCLAIGRLEIVATELAAELGIDLPQLPLVLSAPQWLEEQALADGAFGLAL
                     GLPLHLALPPFITGGKLVTEVLTEKLKDLTGGHVIVNPDPKSSANQLEEIIIDRRKNL
                     GLKDVECNA"
     gene            9480..9953
                     /locus_tag="KR294_002916"
     CDS             9480..9953
                     /locus_tag="KR294_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HBH0240978.1"
                     /translation="MHRIFINKDLCTGCKSCVLACMLKHNKDYDMYTLDLENIDNDSR
                     GHIELDSRHNNPVPILCRHCDEPECVLACMSGAMHKDSESGIVSYDEEKCGSCYMCVM
                     SCPYGLLKPDDRSKQNILKCDLCKDEEYPRCVANCPSGAIELQKEENDELCSVRG"
     gene            9928..11154
                     /locus_tag="KR294_002917"
     CDS             9928..11154
                     /locus_tag="KR294_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBH0240979.1"
                     /translation="MNYVVLGASAAGINAVKTLRELDKDSNIVVISKDENVYSRCMLH
                     HVISEHRTLKQINFVDEDFMEQNNVKWIAGKTVKGIDINKKVVQTEDITVNYDKLLIA
                     TGASSAIPPIKNLRDGNFVYSVRNIDDIYKIKEKAQNSKNVVIIGAGLVGIDALVGLF
                     KYEQLNISVAFMEKYILDRQLDEYTASVYENKFKEKGVKFYPSASIQEIVLDNSKNVT
                     GVAFSNGEVLDADMVIVATGVKPNADFLDGTGIEYDRGIIIDDMCQTTQKDIYAAGDV
                     VGKNAIWPLAVKQGIVAAYNMVGKDKKIEDEFAFKNSMNFMDIPTISIGMNTPVDDSY
                     KVLTRHGINDYKKFVFKDNVIYGAVIQGDISYVGVLTYLIKNKVEIYDLENRIFDICY
                     ADFFNIKENGEFCYSV"
     gene            complement(11293..12480)
                     /locus_tag="KR294_002918"
     CDS             complement(11293..12480)
                     /locus_tag="KR294_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBH0240980.1"
                     /translation="MNITKNFLKDYLEKFGETPFLVRLKDEEEFLIGEGSPQFKVIVN
                     NDISKSELLKSTSLALGEAYINRDIEVEGDLFLTLNLLLKQIDKFNIDNSAVKHLLHS
                     SNSMRHQKKEIHAHYDIGNDFYSLWLDKTLSYSCAYFRNDNDTLYDAQVNKVHHILTK
                     LNLEEGMSLLDIGCGWGFLLIEAAKKYKIHGVGITLSEEQFKEFNARIKEENLQDYLE
                     VRLMDYRELKKSDLMFDRVVSVGMLEHVGRENYELFIKNVNAVLKDGGLFLLHYISGL
                     QESYGDPWIKKYIFPGGVIPSLREMIHICSDYKYHTIDVESLRLHYVKTLLYWQKNFS
                     ENLPKIKEMFDDKFIRMWDLYLCSCAAAFNTGIIDIHQILFTKGIKNDLPLTREYMYN
                     CSK"
     gene            12753..13577
                     /locus_tag="KR294_002919"
     CDS             12753..13577
                     /locus_tag="KR294_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HBH0240981.1"
                     /translation="MEVYALVGSSGTGKSFKALEFAYENDIEYIIDDGILIYKNKVLA
                     GISAKQANTTIEAVKRAIFYNLEHRQEVREAIKKENIRKILIIGTSKKMVNQIVERLS
                     IGRVCKFINIQDISTKYEIEIAKQARKEGNHVIPVPAVEIKSMASGLSINSLKRLFRK
                     GNNRNMVVLEKTIIRPTFSYIGKFYISADVIKQIIEYEVYNFGSIDRINKINIENCNN
                     FMNIFVSININDLETIKKIEDIQQTIKKSIEKMTLVNVQKIDINIHKIKKINFLQC"
     gene            13706..14971
                     /gene="gluD"
                     /locus_tag="KR294_002920"
     CDS             13706..14971
                     /gene="gluD"
                     /locus_tag="KR294_002920"
                     /EC_number="1.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-specific glutamate dehydrogenase"
                     /protein_id="HBH0240982.1"
                     /translation="MSGKDVNVFEMAQSQVKNACDKLGMEPAVYELLKEPMRVIEVSI
                     PVKMDDGSIKTFKGFRSQHNDAVGPTKGGIRFHQNVSRDEVKALSIWMTFKCSVTGIP
                     YGGGKGGIIVDPSTLSQGELERLSRGYIDGIYKLIGEKVDVPAPDVNTNGQIMSWMVD
                     EYNKLTGQSSIGVITGKPVEFGGSLGRTAATGFGVAVTAREAAAKLGIDMKKAKIAVQ
                     GIGNVGSYTVLNCEKLGGTVVAMAEWCKSEGSYAIYNENGLDGQAMLDYMKEHGNLLN
                     FPGAKRISLEEFWASDVDIVIPAALENSITKEVAESIKAKLVCEAANGPTTPEADEVF
                     AERGIVLTPDILTNAGGVTVSYFEWVQNLYGYYWSEEEVEQKEEIAMVKAFESIWKIK
                     EEYNVTMREAAYMHSIKKVAEAMKLRGWY"
     gene            15184..15774
                     /locus_tag="KR294_002921"
     CDS             15184..15774
                     /locus_tag="KR294_002921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M56"
                     /protein_id="HBH0240983.1"
                     /translation="MHFKSKDLNLKYLVLFLKIVYWFNPFICIMEKYMDLDCELYCDE
                     RVLKNCTVQQKQEYALTIVNSMKRSTNFSNKFVAGLNKQSDIRKRVINMFSEKHKNGI
                     LRALIISLFSSITFFKFDSTSIIEENDFLERSRYTFEGRQEDMFVTIDFIYADVPIKL
                     RKEHEENCRVNGIVPKDSDSIEIIPRFYKDCMDLKK"
     gene            16104..>16293
                     /locus_tag="KR294_002922"
     CDS             16104..>16293
                     /locus_tag="KR294_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M56"
                     /protein_id="HBH0240984.1"
                     /translation="MSNFILNGIFRTVIVSSLSILLILIFKKNVFKRFSKKFNYYIWM
                     IVVIKLFLPFTYYTFTINI"
BASE COUNT         6240 a         1937 c         2664 g         5452 t
ORIGIN      
        1 aattatatta aaataaatta tatatgaaaa tatatatgta taagtttatt ctgcgtgagt
       61 agaatggatt tgtcaagttt aatttagttg taattctatc ttttattaaa aataacataa
      121 attaaaacat ataaataaaa tattttatac aatatattgt aaaggaggta actttgatga
      181 aagcagaaaa aacaagtata tatccaatta ttaaaaataa tttaaacaaa atatcaattg
      241 ttgaatataa aaagggtcaa agatttgtag catcagataa agacttacaa gaagtgttct
      301 ttataataga gggagttgca ttagtggagt gtactactag aggaggaaat aaatttcttg
      361 ttgacattgt acctgaaaat gaatttatag gcaaaattag ttacatatat gaacataatt
      421 tgaaatgtga tatatttgca aagactaata taaaattatt tcgatttgaa aaaaatgtat
      481 ttgaagagtt ttatctcaaa ccagatttta ttgcactatt tcacagaaaa tgtacaagaa
      541 gaatatatga attatataaa accagaatgg taagagaact attttcttgc acagaagtta
      601 ttgcctattg tatatcaaat aaacaagaaa ataatgtctg caatataaaa gctattcgta
      661 atttcagtga aatctattca attagtagaa aaagtagata ccattctctg ctaaagttaa
      721 ctgaaaagga gatagtaaaa aaaatgggta atacatatga aattttaaac tatgatgaat
      781 tacataaatt ggcatttgaa gtaaaagaat ttttggaaga tgagtaaaaa ttgttactta
      841 atcaaaataa agtataataa tttctgtaaa aaatagaaat agtctcactg aaaatcaaaa
      901 atactttagt tattttcaat gagactgttt agaaatattg tatacttata atgtatagta
      961 taattattaa tcaatttcct ttactatatt aatagcccat tttttagata atgctctagg
     1021 aacaccaaat ataaacttaa ccacttcttc actataagtg agcaaaacga gtacaaatat
     1081 aggtgcacct ttaaatgcag ctataaaagt tagaggaata gaagctaacc acatacatcc
     1141 taattctaaa aatagagcat atttagtatc tcctccactt cttaaaatac caattataac
     1201 caatgtatta aaagatttaa gagccattag tattcccatt ataaagaata tcttagttat
     1261 atcagaagct aagctatcag aaacactaaa catttttaat aataatggta tatttaaaat
     1321 taaaataatt ccaagtatta aaccagctga aaatacaagt atagaaaact ttttagcata
     1381 ttcaatggct cttttaatat ggtcagctcc aagttcattt ccaagcataa tagatgcacc
     1441 agatgcaata catacagctg tcattatgaa gaaattacct gtactggttg ctatctggct
     1501 agctgctata gcagaagtac cagctcttgc atatgcaaca gaatacagga cagttccaat
     1561 tgcccataca gagtcattta caaatatagg aaagcttttt gatgaaaaag attttataaa
     1621 aattttatca atagctttta gattttttag accaaacttt aatatatagt cttttttata
     1681 aaggtaaaca taagtaatca ttaaaattaa ttcacatatt ctagcaataa cagtagctag
     1741 agcagcacct tttacaccca atgcaggaag accgaagtta ccaaatataa atccataatt
     1801 taaaataaca tttgttacaa gtgcaaatgc actacaaatc atacctaact taggatttct
     1861 aacacctctt gaaccagtac taaatacagt acttacagca attaatggat aactaaatac
     1921 tgcaatacta aagtaatcta tacaaagttt taccacctca gaatcatacg aaaatatgtg
     1981 tataattggc tttggtgtta gtaaagcagg aataacaaat acaaaactta aaacaattgc
     2041 caatacacaa gtaagacctg tgacttttct tatattactc acatccttct ttccataaaa
     2101 ctgtgaaata aaaactccag cacctcctgt gataccagat aaggacatat taaaaagaaa
     2161 gaaaaattgg tttgcaactc caactgaagc tacagatgtt tcccccaaac tacttatcat
     2221 aattgtatct attacattta cagaagtaga aattaagttc tgtatgataa taggtataca
     2281 taaagataga agtattttat aaaatctttt attttcgtct tttaaagaaa atagttcttg
     2341 caaataatcc tctccttttt acataaattc ttcccactca tcatatagag aggcaaggtt
     2401 attttctaaa ttaatttttt cttggctaac ttctttagct ttatctggat tagagtatac
     2461 ttcttcttga cataaaagta tatctaattt ttcaatttca atctctaact tttcaatttc
     2521 tttttctata ttttgtcttt ttattctatt tttcttttct atttctcttt gttctctctc
     2581 ttttcttttt tcatctttta tttgagttct agttttttct tctttttctt ctataatact
     2641 catctcttgg atttgccttt ttttatctat ataataatca taatttccca gatattcagt
     2701 aattccattt tcatctaaaa ctaaaatttt atcaacaaca gtatttagaa agtatctatc
     2761 atgtgatatt gtaaatatag tcccatcata attagttaag gcctcttcaa ggacttcctt
     2821 agaatcaata tctaggtgat tagtaggctc atctaataac aataagtttg catttgatag
     2881 tataagttta agtatggcaa ctctagctct ttctccacca ctcaatgtag aaatcttctt
     2941 aaaaacttct tcatctacaa ataaaaatgc ccctaacata tttctcaaag tagtttgagt
     3001 aagatgagta ttattttccc aaatctcatc aattattgtg ttatctaaat taagagtttt
     3061 ttgttcctga tggaagtagg aaacatgtac attagttcca aatttaatat tgccactaag
     3121 aggttgtagt tcattagtta ttattttaaa taatgtagat ttgccaacac catttgcacc
     3181 tataagtgca actttttccc ctctatatat atctaaatcc aagtctttaa aaagtattct
     3241 ttctccataa cccatagata catctctaat ttgaagaaca tcattaccac tctggacaga
     3301 aggcgtaaat tgtatacgag cttttttcct ataagcttct ggtttatcta aaacatctac
     3361 tttgtctaat gctttttctt tacttcttgc acgctttagg tgtttttctc taccataagc
     3421 ttttagtctt tcaattgatt cttcttgctt ttttatttct ttttgttggt cttcaaattt
     3481 cttaagctct agttcttttt ctattttaga taactcaaca aatttagagt agttaccatt
     3541 atatacttta agctttttat tgtgaacttc aaaaattcta tttacggatt ggtctaagaa
     3601 atatctatca tgagatatta acatgacagt ccctttatat tgttttaaaa atacttctaa
     3661 ccattctatt gcttcagagt ctaagtggtt agtaggttca tcaagtaaca atagagttgg
     3721 tttcttaaga agtaattttc ctaaaagaac tctagttttt tcaccaccag aaagtatgct
     3781 tattggctta tccatatcat tgtcactaaa tcctaatccc tttagaactc ctttggcttc
     3841 agatttatat ccatatccat ttaaatctga aaataattct agtttatgtg aatattcatc
     3901 catgattttt tctataattg gagagtttgt ttttgtactt tcttcagata ttttaacctc
     3961 caattctctt aaataggatt ccatttctat caaattttta aaaacttcta gtacttcttc
     4021 caaaatagta ttatccgaat aaaaattggt attttgttct aaatatccga tttcacaatc
     4081 tttagaagtg taaatatctc cactatcata tccataaatt cctgaaatta ttttaaataa
     4141 agtagttttt ccagtaccat taacaccgat tataccaatt ttatcgcctt catttactgt
     4201 aaaactaata ttttctaata tagaatctat accaaaactt ttatttaagt tattacatga
     4261 caaaacaatc ataaatttct acctccttga actatctaaa attataatgt tttgatataa
     4321 tataatcaag gttatatgta ttagttttga aaaagaaata ttttattgtg aatcaaacaa
     4381 aaaagaggac acttttagga ggtgaagatg ttgggaaata aaaatatatc aatggcagtt
     4441 ataagaaggc tcccaaaata tcatagatat cttggagact tattagatag ggatatacaa
     4501 agaatatctt ctaaagaatt gagtgatata atagggttta ccgcttctca aataagacaa
     4561 gatttaaaca actttggtgg atttggacaa caaggatatg gttataatgt agaagctctt
     4621 catactgaga taggtaaaat tcttgggttg gatcgaccat acaacgcagt tcttgtagga
     4681 gcaggtaact taggacaagc tatagccaat tatgcaggat ttagaaaagc tggattcgag
     4741 ataaaagctt tatttgatgc aaatcctaga atgataggtt taaagataag agagtttgaa
     4801 gtattagatt cagatacttt agaagacttt ataaaaaaca ataatataga tattgctgta
     4861 ttatgtatac ctaaaaatgg agcacaagaa gttattaata gagttgtaaa agctggaatc
     4921 aaaggtgtat ggaattttgc acctttagat ttagaagttc cgaaaggtgt tatagttgaa
     4981 aatgtaaact taacagaaag tttatttacc ttatcgtatt taatgaaaga aggaaagtag
     5041 acaacttaaa catattaata atgagcagtt gtaaagagta ttgagaaagt cagaagattt
     5101 aatattaaat cctctggctt tttgaaatat taggataaaa atttaaataa tgtatggaaa
     5161 taaacaatat taaggagagt ggtttttgtg gaggaattat ggaaaaaggc aattgaattt
     5221 catggtcatg aatgtccagg gttagctata ggatttaaag cagcacttgc agcaaaaaaa
     5281 tatttaggat gtaaacagtc aggagatgag gaaattgtat gtatttctga aaatgatgct
     5341 tgtggaatag atggtataca agtagtgcta agttgcacaa tgggtaaggg aaatttacta
     5401 cttaggatga ctggaaaatc agtatatcat ttctttaata gagaaaatgg aaaatctata
     5461 aggatatatg taaagtcaaa accatttgag atggatagag aaggatacaa aagatattta
     5521 ttagaaagtg attttgaaga aatatttgag attacagata ctaagttaag acttcctgaa
     5581 aaagcaagaa tatttaaatc ccttaaatgt gaagtgtgtg gtgaatttgc atctgagcaa
     5641 tatataagga ttgaagaagg aaagaaagta tgtcttgatt gttttgataa atatgaaaga
     5701 ttttatgaag agtattaaaa ttataaatta gattaaagtt aaaagtatta gatatgtgct
     5761 aacagtattt taagatgaat taggtagcaa cataataaag tatataaata atattaattg
     5821 aatcatacat aattaaaaag aggctgatta gtatttataa aataaaatca gtctctttat
     5881 gaataacgaa ttattattct ggttgaggtg catctacagg acaagctcct gcacaagaac
     5941 cacagtctat acaagaacca gcatctataa catatgcgtc gtctccagct gatatacagc
     6001 taacagggca ttcagcctca caagcaccac agcttataca agcgtcagta attttatatg
     6061 ccattttgaa atcctccctt ttatatgtat tgtaattcaa taacattata acaaatatta
     6121 ttgaatataa caattaaatt aattctacaa caaaaacttt attatgatat tcttgtttta
     6181 aagttttaca ataaagttta atctgcttat atttttattt attttaaaga agtttatttt
     6241 aaaaataaaa ttaaatttaa aaagttatgt attgattata tttaaaaatg ttatactcta
     6301 aaaaagtata ttttatttaa aaatttatta atacaaagga gatttactat gaaaaataaa
     6361 ttagtttaca tatgtattat gagtctattg ctatttgtag taggatgttc taataatcca
     6421 aataaggaaa gtaccattaa aaaagactct aagaataacc aaagccaagt taaagaagaa
     6481 aaaagagaac ctgtgaaaaa agatataact ataagtttcg ctggtgatgt aactatgggg
     6541 aactataaag gttcatcata ttatggcagt tttgaccatg aatttaaaag acaaggagaa
     6601 gattacaatt attttcttaa aaatgtaaaa cctgtatttg aaaaagatga cttaacagtg
     6661 gttaatttag aaggtccact tactacagcg tcaaatgcaa aagaaaaaaa atttgcattt
     6721 aaaggaaagc ctggatatgt aaatatttta aaatctggaa gtgtagaggc agtaagtatt
     6781 gcaaataatc attcagaaga ttattttgaa gaaggaatga aagatacaca gtttatattg
     6841 gacgagaata aaataaatta ttttggatta gggaaagatg ctgttgtaga tgtcaaagga
     6901 attaaagtgg gtctattagg gtataatgga ttatcaactg aatataatga aaaaaattta
     6961 aaacaaatgg aagatgatat taagtcctta aaaaagaaat cggatgttgt tgtagtgtac
     7021 tttcattggg ggatagaatt agattattat ccagataaaa aacaaaaaga ttttgctcat
     7081 tatgctatag acaagggagc agatttagtt atggggtctc acccacatgt gattcaagga
     7141 atagaaaagt ataaaaataa gtatatagct tatagtctag ggaatttttg ctttggagga
     7201 aataagaatc cttctgatac agatagttat atatatcaac aaacctttac tttttcagat
     7261 aataaattaa cttcaattaa agagccaaat ataataccaa cttcaataac atctagtaac
     7321 tccagaaata attatcaacc aaaaatattg gatggaagtg agaaggatag agttttaaat
     7381 aaacttgaaa aaataagcaa agatttaaat aaataaaatg taaaaaaaaa taaatatata
     7441 tatttatttt aataatttat attttgttta gggtatggta aatcgtggta ttaaataagt
     7501 agattttaat agttaaatta tagtcaatta taataaagct atttaatcta cttttttaat
     7561 ataaaaatat aagggggaat ttgtaatggc ttgtaacact tgtaaaatgt gcgaaagtgc
     7621 agacaagaaa ttagaaagtt ttgtagcttc aaaggatgtt gaaacagcat ttcatagaac
     7681 agaagatcag aaagttaagt gtggttttgg acttcagggg gtttgttgta gactctgttc
     7741 aaatggacca tgtagagtaa ctcctaaatc accaagaggt atatgtggag cagatgcaga
     7801 cactatagta gcaagaaact ttttaagagc agtagcatca ggagcagctt gttatttaca
     7861 tgtggtagaa aatacagcta agaatttaaa aaatgttgga ataactaaag gtgttgttaa
     7921 aggagaaaaa acattaaatc aattagcaga gatgtttgga atagaaagtg atgaaaagta
     7981 tgataaatgt ataaaggttg cagacaaagt tatcaacgat ttgtataaat caagagatga
     8041 taaaatggaa ttagtagaaa aaatagctta tgcacctaga gtgaaaaagt ggaaagagtt
     8101 aggtataatg cctggtggtg caaagtcaga agtttttgat gcaatagtaa aatcatcaac
     8161 aaatttaaac agtgacccag tagacatgct agttaattgt ttgaacttag gtatatcaac
     8221 aggattatat ggtcttacac taactaatct tttaaatgat gttatgttgg gagaaccagt
     8281 tataagaatg gctcctgtag gatttaatgt aatagaccca gactacataa atataatgat
     8341 aacaggtcat caacattcaa catttgcaaa tttccaagat agattaaaag atgaagatgt
     8401 tataaaatta gctcaatctg ttggcgcaaa aggatttaag ttagtaggat gtacatgtgt
     8461 tggtcaagat ttacaattaa gaggagaaca ttatcaagaa gtatttgctg gacatgcagg
     8521 taacaatttt acaagtgagg ctgttttatc aactggagca atagatatag ttctttcaga
     8581 atttaactgt actataccag ggcttgaacc aatagcagat aaatataaag taaaaatggt
     8641 ttgtttagat gatgttgcta aaaaagcgaa tgcagaatgc ataggtttag acagaagtaa
     8701 attagatgaa cttagtaaca ctttaataga aaaagcattg gagtcttata aggagagaag
     8761 aggaagtatt gaaatagata taccaaaaga ccatggattt gaacaatctt tgactggtgt
     8821 aagtgaaaag aacttgaaag cgtttttagg agattcatgg aaacctctta ttaatttaat
     8881 tgcagaagga aaaattaaag gtgttgcagc tgttgtagga tgttcaaata tgacagcagg
     8941 aggacatgat gtaaatactg ttgaacttac taaagaattg attaaaaaag atataatagt
     9001 actatctgca ggatgttcta ctggaggatt agaaaatgtt ggtcttatgt cacctggagc
     9061 agaagaattg gcaggagaaa acttaaaaga agtatgtaag actttaggaa taccaccagt
     9121 attaaacttt ggaccatgtc tagctatagg aagactagaa atagtagcaa cagaattagc
     9181 agctgaactt ggaattgacc taccacaatt accattagtg ctttcagctc cacaatggtt
     9241 ggaagaacaa gcattagctg atggagcttt tggtcttgcc cttggcttac ctcttcattt
     9301 agctttacct ccatttataa caggaggaaa attggtaaca gaagtattaa cagaaaaatt
     9361 aaaagactta acaggaggac atgttatagt gaatccagac cctaaatctt cagctaatca
     9421 attagaagaa ataataatag atagaagaaa aaatttaggg ttaaaggatg tggaatgcaa
     9481 tgcatagaat ttttataaat aaagatttat gtacaggatg taagagctgt gtactagcat
     9541 gtatgctaaa acacaataaa gattatgaca tgtacactct tgatttagaa aatatagata
     9601 atgatagtag agggcatata gaattagata gtagacataa taatccagtt ccaattcttt
     9661 gtagacactg tgatgaacct gaatgtgtat tagcatgtat gagtggtgca atgcataaag
     9721 atagtgaaag tggaatcgtt tcatatgatg aagagaaatg tggttcatgt tatatgtgtg
     9781 taatgtcttg tccatatgga ttattaaagc cagatgatag aagcaagcag aacatactta
     9841 aatgtgattt atgtaaagat gaggagtatc ctagatgtgt agctaattgc ccaagtggag
     9901 caattgaatt acagaaggag gaaaatgatg aattatgtag tgttaggggc tagtgcagct
     9961 ggtataaatg cagtaaaaac attaagagaa ttagataaag attcaaatat agtagtaatt
    10021 tctaaagatg aaaacgtata ttcaagatgt atgttgcatc acgttatatc tgaacacaga
    10081 actttaaaac aaataaattt tgttgatgaa gattttatgg agcaaaataa tgtaaaatgg
    10141 attgcaggta agactgttaa aggtatagac ataaataaaa aggtagttca gacagaagac
    10201 attactgtaa attatgataa acttttaata gctacaggtg catcttctgc tattcctcct
    10261 ataaaaaatt taagagatgg aaattttgta tattctgtga gaaacataga tgatatttat
    10321 aaaataaaag aaaaagcaca aaattctaaa aatgtagtta taataggtgc tggtttagtt
    10381 ggtatagatg cattagtggg attatttaaa tatgagcagt taaatatttc tgtagctttt
    10441 atggaaaagt acattttaga tagacaattg gatgaatata cagcatcagt gtatgaaaat
    10501 aagttcaaag aaaaaggtgt aaaattttac ccaagtgcat caatacaaga aattgtattg
    10561 gataacagta aaaatgttac aggtgttgca ttttcaaatg gtgaagtttt agatgcagac
    10621 atggtaattg tagctacagg ggttaaacca aatgctgact ttttagatgg aacaggaata
    10681 gaatatgata gaggtataat aatagatgat atgtgccaaa caacacaaaa agacatatat
    10741 gcagcaggag atgttgtagg taaaaatgct atttggcctc tggcagtaaa gcaaggaatt
    10801 gtagctgcct ataatatggt tggaaaagat aagaagatag aagatgaatt tgcttttaaa
    10861 aatagtatga atttcatgga tataccaact atttctatag gaatgaatac acctgtagat
    10921 gatagctata aagtattaac cagacatgga attaatgatt ataaaaagtt tgtttttaaa
    10981 gataatgtaa tctatggagc agttatacaa ggagatattt catatgtagg tgtattaact
    11041 tatttaataa aaaataaagt tgaaatatat gatttagaaa ataggatatt tgatatatgt
    11101 tatgcagact tttttaatat aaaagaaaat ggagaatttt gttatagtgt atagtatata
    11161 cgtggagtaa ggtttataaa tacagtaaat caataaatag agttattcta aaataagaaa
    11221 aatgacaaat cttatttaga aatagctcta ttttttgtaa ttaaatttaa attatattca
    11281 atttgtaaaa tattattttg aacaattata catatactct ctagttagag gtaaatcatt
    11341 ttttatacct ttagtgaaaa gtatttgatg tatatctata ataccagtgt tgaaagcagc
    11401 agcacaagaa caaaggtata aatcccacat tcttataaac ttatcatcaa acatttcttt
    11461 aatctttgga agattctcag agaaattttt ttgccagtat agtaaggttt ttacataatg
    11521 taatcttaaa ctttctacgt ctatagtatg atatttgtaa tcactacaaa tatgtatcat
    11581 ttctcttagg ctaggaataa ctcctcctgg gaaaatatat ttttttatcc aagggtctcc
    11641 ataagattcc tgcaatccac ttatatagtg aagtaaaaac aatccaccat cttttaaaac
    11701 agcatttacg tttttaatga aaagttcata gttttctcta ccaacatgtt caagcatccc
    11761 aacgcttaca actctatcaa acataaggtc tgattttttt aattctctat agtccataag
    11821 tcttacctca agatagtctt gaaggttctc ttctttaatt cttgcgttaa attccttaaa
    11881 ttgctcttcg ctaagtgtaa ttccaacgcc gtgaatttta tatttttttg cagcttctat
    11941 tagtaaaaat ccccaaccac aaccaatatc gagaaggctc ataccttcct ctaaatttag
    12001 tttagttaat atgtggtgaa ctttattgac ttgagcatca taaagagtat cattatcatt
    12061 tctaaagtat gcacaagaat aactaagtgt cttatctaac cataagctat aaaaatcgtt
    12121 gccaatgtca tagtgggcat gtatttcttt cttttgatgt ctcattgaat ttgatgagtg
    12181 caatagatgt tttacagctg aattatcaat attgaatttg tctatttgtt ttaaaagtag
    12241 atttaaagtt aagaataaat ctccctcaac ttcaatgtct ctatttatgt aggcttctcc
    12301 aagtgctaaa gatgtacttt ttaatagttc agacttgcta atatcattat ttactataac
    12361 tttgaactga ggggagccct ctccaattag aaattcttcc tcatctttaa gcctaactag
    12421 aaatggtgtt tcaccaaatt tctctaaata gtcttttaaa aaattttttg taatattcat
    12481 attaccagct ccttctaatg taaatccagt aagtttccct gcttaaaata tattatagtc
    12541 ctttttttaa aaaagtaaaa ttttttcaat aaatttttta tttaaaggaa atttattttt
    12601 tgtaaagaaa tttcatgttg tagtatattt tttgcttata aattttggta ctggatataa
    12661 tattaaactg ttaatgatat aataaattta atctataaag taaataaaat tttgtaataa
    12721 atagttaaag ctattttata aggagatata tgatggaagt atatgctttg gttgggtcaa
    12781 gtggcacagg gaagagcttt aaggctttag agttcgcata tgaaaatgat atagaatata
    12841 taattgatga tgggatttta atatacaaaa acaaggtttt agctgggata tcggcaaaac
    12901 aagcaaatac tactatagaa gcagttaaaa gggctatttt ttataatctg gagcatagac
    12961 aagaagttag agaagcaatt aaaaaagaaa atataagaaa aattcttatt attgggacat
    13021 caaaaaaaat ggttaatcaa attgtagaga gattgtcaat tggaagggtt tgcaagttta
    13081 taaatataca agatataagt actaaatatg aaatagaaat agcaaaacaa gctagaaaag
    13141 aaggaaatca tgtaattcct gttccagcag ttgagataaa aagtatggca agtggtctta
    13201 gtataaattc tttgaagaga ctttttagaa aaggaaataa taggaatatg gtagttttag
    13261 aaaaaacaat tataagacca acttttagtt atataggaaa gttttatatt agtgctgatg
    13321 taattaaaca gattattgaa tatgaagtat acaactttgg aagcattgat agaataaata
    13381 aaatcaatat agagaattgc aataatttta tgaatatttt tgtaagtata aatatcaatg
    13441 atttagaaac tataaaaaaa attgaagaca tacaacagac aataaaaaag tctattgaga
    13501 aaatgacttt agttaatgta caaaaaatag atattaacat tcataaaatt aaaaaaataa
    13561 acttcctcca atgttaaaaa ataaactgag aaaatgatat actaatttgc aataaagtgt
    13621 gctataatta aactgtaaat ttaggaaatg gttttttcta aatggagtat acataattat
    13681 aacgtattta taagggggct ttcaaatgtc aggaaaagat gtaaatgtct tcgagatggc
    13741 gcaatctcaa gtaaaaaatg catgtgataa attaggtatg gaaccagcag tttatgaatt
    13801 attaaaagaa cctatgagag ttatagaggt ttcaattcca gtaaaaatgg atgatggttc
    13861 tataaaaact tttaaaggat ttagatcaca acataatgat gcagtagggc caacaaaagg
    13921 tggaataaga ttccatcaaa atgtttcaag agacgaagta aaagctttat ctatatggat
    13981 gactttcaag tgttctgtaa caggtatacc atatggtgga ggtaaaggtg gaataatagt
    14041 agatccatca actttatctc aaggtgaatt agaaagatta agtagaggat acatagatgg
    14101 aatatataaa ttaataggtg agaaagttga cgttcctgca ccagacgtaa atactaatgg
    14161 tcaaataatg tcttggatgg ttgatgagta caataaatta actggacaaa gttctatagg
    14221 tgttataact ggtaagccag ttgaatttgg tggttcttta ggaagaacag ctgctactgg
    14281 atttggtgtt gctgttactg caagagaagc tgctgctaaa ttaggaatag atatgaaaaa
    14341 agctaaaata gctgttcaag gtataggaaa cgttggttct tatacagttc ttaactgtga
    14401 aaaacttggt ggtactgttg tagctatggc tgaatggtgt aaatcagaag gttcttatgc
    14461 tatatacaat gaaaatggtt tagatggtca agctatgtta gattatatga aagaacatgg
    14521 taacttatta aacttcccag gagctaagag aatatcttta gaagagttct gggcttcaga
    14581 tgttgatata gtaataccag ctgcattaga aaactctata actaaagaag ttgctgaatc
    14641 tataaaagct aaattagttt gtgaggctgc taatggacca actactccag aggctgatga
    14701 agtatttgct gaaagaggaa tagttcttac tccagatata ttaactaatg ctggtggagt
    14761 tacagtttct tacttcgagt gggtacaaaa cttatatgga tactactggt cagaagaaga
    14821 agtagagcaa aaagaagaaa tagctatggt taaagcattt gaatctattt ggaaaatcaa
    14881 agaagagtac aatgttacaa tgagagaagc tgcttacatg cattcaatta agaaagttgc
    14941 tgaagctatg aaattaagag gatggtacta agatttactc ttaataaata ataggatata
    15001 attatttaag atataaaggg gctgtacata gtacagccct taaattatgt ggcttacaat
    15061 gaagtaagct atttttgttt taacttataa ataacttgat aaattatgta atttagaatg
    15121 tattttttac caccacatga ttacaaatta gaggagttag attgaatttt tagacatgaa
    15181 cttatgcatt ttaaaagcaa agaccttaat ttaaagtatc tagtattatt tttaaaaata
    15241 gtatattggt ttaatccatt tatatgtata atggaaaaat atatggattt ggattgtgaa
    15301 ctttattgtg atgagagagt tttaaaaaat tgtactgtac aacaaaagca agaatatgct
    15361 ctaactattg taaattcaat gaaaagaagt acaaattttt caaataaatt tgtagctgga
    15421 ttaaataaac aatctgatat tagaaaaaga gtaataaaca tgttcagtga aaaacataaa
    15481 aatggtatct taagggcttt gattataagc ttgttttctt ctattacatt ttttaaattc
    15541 gattcaacta gtattattga agagaatgat ttcttagaga ggtcaagata tacgtttgaa
    15601 ggaaggcaag aagacatgtt tgtaacaata gattttatat atgcagatgt acctataaaa
    15661 cttagaaaag agcatgaaga aaactgtaga gtcaatggaa tagtaccaaa agattcagat
    15721 tcaatagaaa ttattcctag attttataaa gattgtatgg atttaaaaaa ataagttaga
    15781 cttaatattg atgttgatat tatgaatttt ttatatttaa gcaattgaaa attttattat
    15841 agattcaatt ttatatgtgt ttaagtatga aatttataga tagttgaaat aattaaatat
    15901 gattgatgca taggaatcat tactaagcta taattaatta taggggagtt taaataaatt
    15961 atgagttaca caatcataaa atgataaaaa tagttatctg ttacaaaaaa tgtatctttt
    16021 taattaataa agataatatg aaaacttaaa aggcaaataa acttaaatat aaaatactct
    16081 taaataagat aggagaaaaa tgtatgtcta actttattct aaatgggatt tttagaacag
    16141 ttatagtaag tagtctaagc attcttctga tattgatttt caagaaaaat gtatttaaaa
    16201 gatttagcaa aaaatttaat tattatatat ggatgatagt tgttattaaa ttatttttac
    16261 catttacata ttatactttt acaataaata tct
//
LOCUS       DAEPKC010000091        16222 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.091, whole genome shotgun sequence.
ACCESSION   DAEPKC010000091 DAEPKC010000000
VERSION     DAEPKC010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16222)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16222)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16222
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.091"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            274..816
                     /locus_tag="KR294_002923"
     CDS             274..816
                     /locus_tag="KR294_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBH0240985.1"
                     /translation="MKICITVGHSILKGGKSTGVNGIVDEYNYNKKLAPMLAEMLISQ
                     GNTVDVIICPERHFMSEREEFFYRVPKVNSGKYDLLVELHLNKADGTQCGTEVLYYGT
                     EGLEYAKRVSNRLGELFENRGAKKRENLYILRNTNPVAIQIESFFCDNVNDCNKANES
                     GYDYIARLITEGILNKDINM"
     gene            1144..2637
                     /locus_tag="KR294_002924"
     CDS             1144..2637
                     /locus_tag="KR294_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBH0240986.1"
                     /translation="MKYTFEKFKLNEKILKSLKSLGYNIPSRVQREVIPKLLKGQNLV
                     VRSKTGSGKTASFAIPLCENINVDYNNIQALIVVPTRELALQVKDEISDIGRLKKVRC
                     SAIFGKQSIKDQIAELKQRVHIVVATPGRILDHINRGSIKLENVKYLVIDEADKMFNK
                     GFVEQMEKILLNLPKEKIVSLFSATIDEEIKYICEKYMLDYSVINIEENESDTNQKTR
                     QIDDKIIKANGREKYILLKELIYSENPKSVIIFCNTKEKVSKLYNKMSKEGFLIRELH
                     ADLSQERRIFVIKDFKNQKFNVLVSSDVASRGIHIDDISLVINYDVPQDKENYIHRIG
                     RTGRKGNSGKAITIVTEKDEKYIENIETYIGYKINELKDIEKSRITHGKILFEEYSKG
                     ILKKVSKRKKVDKNSYNSKDIKLNIESEVVKLYLNAGKKKKIRVLDIVGAFSNIKGIT
                     NDDIGVIEVQDLCSYVDILNYKGDLILKKYKEIPIKKKMVKVKRDIR"
     gene            2711..2944
                     /locus_tag="KR294_002925"
     CDS             2711..2944
                     /locus_tag="KR294_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0240987.1"
                     /translation="MKAEDMKRKVSPIDLERILVTGGVIKHEDSIWLLDFWGNKDIAG
                     ILLMPPTRHVILHLNDCCKWKEYFRTKKKFYRS"
     gene            3100..3864
                     /locus_tag="KR294_002926"
     CDS             3100..3864
                     /locus_tag="KR294_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBH0240988.1"
                     /translation="MAYFNYNDKQCYYNEIGDGTPLLFLHGNTASSKMFNDIIDFYKD
                     EYKVILIDFVGHGKSQMVDKFSADLWFDEAMQVICFLEAMNYKKVNIIGSSGGALVAL
                     NVALERPDLVNKVIADSFEGEVPLESFVQNVKIEREASKQDDGAKAFYIYNQGENWEK
                     VVDNDTEAIFEHYKTIGKFFHKPLETMQPEVLLTGSREDEFVSLISSDFFENTFSLLL
                     EKIKNGKMYLFDKGGHPAILSNGLDFSNVAKKFLEE"
     gene            complement(4149..7328)
                     /locus_tag="KR294_002927"
     CDS             complement(4149..7328)
                     /locus_tag="KR294_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBH0240989.1"
                     /translation="MKIDMIYKLIRRNTEPSRWSRGVKYYTNQLVDYIDIDIDDLQNN
                     LLTFRGGVNSEDNYSFYFNSITIDIKHFKIIENDCSCADCQSKGKSIFICKHIVAIVI
                     KSLKQIKNKKDVPPILIDILGADKDKLSNTNSKTSLDLSKQLLSLLDNTKRERVNLDV
                     LINVDSNKAIAEFKIGIDKMYILKNITEFAYSKLNGYELDFGKKFTYNPNTHYFADED
                     EKLVDIIEEYGTNLSYNFSSSHSKKFMEINASSLKQFLNAIKYKDFTLIFSKEEYHPK
                     ILNDTLPVRFDFKNIEDKIVLYSKDSLPVPLTKKNDVLLYDGNIYLLSHKKAHDYSKI
                     YQILSKTKELKFDKEDSKDVLGLLVPRLKSISQEVHLDDNIKNNITKDFKSEFYFDMI
                     DGNICCDVKYIYDDEDKKFVLPNIQKEATIENKLTSSQFTKENNHYVFKGTDHDLFTF
                     LDLQLESLKEFGDIYYSEKFKLKKIYNASSIQASINQTNQNYLEFNFNISDINPREYK
                     DILKAFQEKRTFYKLKDGNFIDLSERETKDFFELVENLDIMDKSKNNKIHKNKALYIN
                     DVIRSKNLKFIDGKKELDSICEKFRNFDSINLEIPANLNANLRDYQINGLNWFKVLDY
                     YKFGGILADEMGLGKTIQTIAFLLSLSNKKSLIVTPTSLIYNWKNEFEKFAPDIKVLL
                     IHGNKRDREKCFMELENFDVILTTYGTLRNDLEKYSEIKFDYCILDEAQNIKNPVALV
                     TESVKSINAENKFALTGTPMENNLLELWSIFDFIMPGYLYSKAKFQELFINKEDNVKN
                     LKKLIKPFILRRSKKQVMKELPDKIEKNFFVELNKEQKKIYSVYSKDIQDKMKDKNLK
                     KDKIVIFSYLTKLRQLCLDPSIVVKDYNKKSSKIETCLEILRDSINENHKILLFSQFT
                     SVLKNISKELDKYKIKYHYIDGKTNAKERLELVDEFNNSMDKKVFLISLKAGGTGLNL
                     TSADMVIHFDPWWNPSVENQASDRAHRFGQKNSVQVIKLIAKGTIEEKIIKLQESKKE
                     LINQFINGELSNEGVLKSLSDEEIINLFN"
     gene            7609..9786
                     /locus_tag="KR294_002928"
     CDS             7609..9786
                     /locus_tag="KR294_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HBH0240990.1"
                     /translation="MYNKYNNLYLLLGKENVNMDSYRQLKAKIPCKETGIEIKRTLCD
                     ICSPGVHCGIDAYVKDGKVIKIEGTKEHPMNKGLLCTKGLCNREYIYREDRIKTPLKR
                     IGKRGEGKFKPISWDEAYREIAEKLNRVKSEYGAKHVAFFTGYGKWYRPFLQRFASSF
                     GSPNYGTESSSCSTSAQMAGNVATGRNFTMQDMENAKTYLGWGFNPYYSKFLNSVNLI
                     KLKEKGLKFIIVDPRITPTTQKLADLHLRIKPGTDGALALGMANLFIQKDLIDREYIE
                     KHVHGFNEYKEYVKLFDLDTVSRITGVSKDNIVKAVEMLSQGPFCINESAAPIVHHQN
                     GFQNYRAMMSLSAITGNYDRIGGNIPKQDYFAGKIGGFQTLEKEFVKEVLPKNINERI
                     GGERFPLWNEMVTQFQAMDLPRQIEEKTPYEIRALFCHGINARMFTNSGRLFKALNSV
                     DFFVNIDLFMTDTSKYADILLPACTSFEREECKSYPGGYITYTKKVIDKLYDSKSDVE
                     ILSDLANAMNIDDDLLKAGYEASIRHMFKNTCVDVDKLKESDLPLKCKDFKPYIVGSY
                     TREGYDTSTSRFELKSTIIEKYKDFGLDALPTYRGFNDNIDDEYTHLLTSGARISNAL
                     HSRLHDIKLSRILKNEASCDISSLDAKELGVISGDYIKITTKIGSLDVKVNVTDRVLY
                     KNIHMYHGYREADINSIICDNFDPYSGFPAYRSCKCKIEKMNR"
     gene            9800..10222
                     /locus_tag="KR294_002929"
     CDS             9800..10222
                     /locus_tag="KR294_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBH0240991.1"
                     /translation="MKSLFKFNKELCTACGACLLACIDQNDNNIDNGELFRHVFTIEE
                     GENIEYFSLACIHCNEPKCLGVCPKNCFKKEEGFIVLDNQNCIGCKLCEKACEYGALI
                     YGNDGKANKCNGCIERYKCGMDSPCVMVCPTGALKFNK"
     gene            10630..11433
                     /locus_tag="KR294_002930"
     CDS             10630..11433
                     /locus_tag="KR294_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HBH0240992.1"
                     /translation="MKKLKLIIMFALVSALLVTGCSSGNNKNKEEQKVIRVATSGTYY
                     PFAFKDKDKLKGFEVDFWDEFAKRTNCKVEWVLTDFSGLFGLLEADKADVVSAQLTAT
                     PEREKKYAFSDAYNYSGTNIIVREDDTSIKSIDDLVGKKVGVGTGAVANEILKEKYPN
                     DEIKIVNYSSATLKGNYQDLEMGRLDAVVAQDVEALIAIKEQKLNLKMIEPPIQFGAC
                     SFALQKNEKGEKWTKEINEVIEEMYKDGTLTKISENWLGKDITKEPINE"
     gene            11426..12094
                     /locus_tag="KR294_002931"
     CDS             11426..12094
                     /locus_tag="KR294_002931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBH0240993.1"
                     /translation="MSNFNFEFCLSIFPFLIKALGITILISIVAFFLSILLGVILAFF
                     TQTKSKVLQYITRVYVSFFRGTPLLIQIFFFYFGFPMIFSFMKDCSPYLAIVICLGVN
                     SSAYMAEIIRASIESVDKGQQEACYAFGLSKYQSMVKIILPQAATSAVPPIVSCTLDI
                     IKGSSLGLTIGIQDLMGVAQVEAASSFKYFEIYMITILIYWAVSIILSNIQSKVEKRI
                     RRAY"
     gene            12330..12992
                     /locus_tag="KR294_002932"
     CDS             12330..12992
                     /locus_tag="KR294_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBH0240994.1"
                     /translation="MAFNMKYFLELFPTIMKSFNVTVILAISSLVFSLIIGTIVALSS
                     YYKVKVLNQICKVYVSIFRGTPLMPQLFFLYFGLAYMSDFVKNMDPVFATSIVLSLNM
                     GAYMSETIRASILSIDTGQIEAAYAMGLTNLQTMKRIVIPQAVRVALPSLFNNFIDLI
                     KGSSVAFVVGVNDIMGAAKSQGALSFKFFEVYGAVMVIYWCIITPLGWGQKKLEKKIS
                     NY"
     gene            13052..13849
                     /locus_tag="KR294_002933"
     CDS             13052..13849
                     /locus_tag="KR294_002933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HBH0240995.1"
                     /translation="MIKRNIIKCLVAVLSLTFVITGCSKKEEVKNEKVITVASSNSAD
                     PYSYVDNGEHKGFEVDMWKEIGKRSGYKIKMEPTGFSSIFGMLDSGKVDVAANFFGMS
                     KERLEKYDASIPYGSDSVCIAVKDGNNEINKLEDLKGKVVAVSEGSQGQQVATSVNKD
                     NLFQEKVYGDGTSGLQDLDLGRVSAWIDAELTIVGDAKKANMKVRVLDKKLSATNIAY
                     FFKKNDDKSKTIKEDVNKAIEEMLADGTVKKISEKWFGMDVSADIQK"
     gene            13967..15157
                     /locus_tag="KR294_002934"
     CDS             13967..15157
                     /locus_tag="KR294_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH0240996.1"
                     /translation="MEVLQMIETKIKSIALKNREKIIKIRRQIHSNPELAFKEYKTSK
                     LIKEELNKLNIEYINIAGTGVLATIKGKNNGGKTILLRADMDALPIKEENDLEFKSIN
                     DNMHACGHDAHVSWLLGTAMILNDIKEELNGNVKLLFQPGEEKGGSDIVIKENVLEGV
                     DALATGHCWPTIESGKIGIARNCAMAATNTFEITIIGKGGHGAEPHNCIDPIAVGNAV
                     YSSIQQIVSRKIDPVVPVVVSVCSFNSGVSKNIIPDVCTLQGTIRAISKEQVIEVSKI
                     LEYIVKNVCKAHGADCKFEKSTGGDAVINDKNMIEIGRESACKILGAENVEIIDFPAM
                     TGEDFAIYMKEKPGLFMYIGVGDKEKNINYRLHSNKFNIDEKCLSIAPSLFSQLTVDY
                     LCQL"
     gene            15266..16015
                     /locus_tag="KR294_002935"
     CDS             15266..16015
                     /locus_tag="KR294_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBH0240997.1"
                     /translation="MIKVENLHKSFKGTEVLKGINLEISQSEVVAILGSSGTGKSTLL
                     RCLNYLVEPTKGKIMIGDVKVDVEKATKKDITNLRKHTSMVFQNYNLFKNKTALENVM
                     EALIVVHKKSKKEAREISLKLIDKVGMLDRKDFYPSKLSGGQQQRIGIARAMAVNPNV
                     ILFDEPTSALDPELVGEVLSVIKSLAKEGITMLIVTHEINFAKEVADKIIFMDNGVIA
                     EEGTPDEIFNNPKNERTAKFLNIIRKEEVFS"
BASE COUNT         6326 a         1691 c         2667 g         5538 t
ORIGIN      
        1 acttaaactt attaaaatag catttggtta aaggaaaata gatattgata tatttatcat
       61 atatataaat gattaattaa acaattataa ataataagta tattataata tttaaaaaat
      121 atagatttat gataaaataa gacaaatatg ttaaaaaaat gataatcacg gagaactttt
      181 accttcttca attaatatat tattattagt aataacttta aaattatatt actattatat
      241 aaaaattggc ttaaaagaag gtgaaaaaag taaatgaaaa tatgcataac agtaggtcat
      301 agtatactaa aaggtggtaa aagtacaggt gtaaatggta tagttgatga atacaattat
      361 aataaaaaat tagctcctat gttagctgag atgcttataa gtcaaggtaa tacagtagat
      421 gtaataattt gtccagaaag gcactttatg tcagaaagag aagaattttt ctatagagtt
      481 ccaaaagtaa acagtggtaa atacgattta ttagtagagc tacatttaaa taaagctgat
      541 ggaacacaat gtggtacaga agtgctttac tatggcactg aaggattaga atatgctaaa
      601 agagtatcta atagacttgg agaattattt gaaaatagag gagctaaaaa aagagaaaat
      661 ttatatatat tgagaaatac aaatccagtt gcaatacaga ttgaaagttt tttctgtgat
      721 aatgtgaatg attgtaacaa agcaaatgaa tcaggttatg attatatagc acgattgatt
      781 acagaaggta tattgaataa agatataaat atgtgagatt atggtgattt aggtattgat
      841 taataccttt taatattaga tataaataaa aatacaatgt attagtataa tttaaacttt
      901 caaaagatag attagtttga ttattgacaa gagatacctc cttgaaaata ttgatttatc
      961 agtatattta aggaggtatt taaatataaa aatttaatta atttgctact aaactatagg
     1021 tttatagagt atatattttt atcttcagtc taataaataa tataaaaata gtagaacctt
     1081 gtattataat aatataatgt agaaaaatat atagataaga taaatataat aaggtggtaa
     1141 tatatgaaat atacatttga aaaatttaag ttaaatgaaa agatacttaa gtcattgaag
     1201 agtttaggat ataatatacc ttctagagta caaagagaag ttattccaaa attattaaaa
     1261 ggtcaaaact tagtagttag gtcaaaaaca ggaagtggaa agacagcaag ttttgcaata
     1321 cctttatgcg agaatataaa tgtagattac aataatattc aagctcttat agtggttcca
     1381 acaagagaat tagccttgca agtaaaagat gagatatcag atatagggag actaaagaag
     1441 gtgagatgta gtgctatatt tggtaaacaa tctataaaag accaaatagc tgaattgaaa
     1501 caaagggttc atattgttgt agctactcca ggcagaatac ttgaccatat aaatagaggt
     1561 tctattaagt tggaaaatgt aaagtattta gtaatagatg aggcagataa aatgtttaat
     1621 aaaggttttg ttgaacaaat ggaaaaaata ttattaaatt tacctaagga gaaaatagta
     1681 agtctttttt cagctacaat agatgaagag ataaaatata tatgtgaaaa atatatgcta
     1741 gattacagtg ttataaatat agaagaaaat gagagcgata ctaatcaaaa aacaagacaa
     1801 atagatgaca aaataatcaa ggcaaatgga agagagaagt acatcctttt aaaagaatta
     1861 atatacagcg aaaatccaaa gagtgtgata atattttgta ataccaaaga gaaagtatct
     1921 aaattatata acaagatgag taaagaaggt tttttaataa gagagttaca tgcagattta
     1981 tcacaagaaa gaagaatttt tgtaattaag gattttaaaa accaaaaatt taatgtatta
     2041 gttagtagtg atgtagcgtc cagaggaata catattgatg atatttcttt agtaataaat
     2101 tatgatgtgc cacaagataa agaaaactat atacatagaa taggtagaac tgggagaaaa
     2161 ggaaatagtg gaaaggcaat tactatagta actgaaaagg atgaaaaata tatagagaat
     2221 atagaaacgt atataggata taaaataaat gaattaaaag atatagaaaa aagtagaatt
     2281 acacatggca aaattttgtt tgaagaatat tcaaaaggaa tcctaaaaaa agtatcaaag
     2341 agaaaaaaag ttgataaaaa ttcttacaat agtaaagata taaaactaaa tatagaaagt
     2401 gaagttgtta aattatattt aaatgctggt aagaagaaga aaataagagt tttagatata
     2461 gttggtgcat ttagtaatat aaaaggtata actaatgatg atataggtgt aattgaagtt
     2521 caagatttat gttcatatgt agatatatta aattataagg gagatttgat attaaaaaaa
     2581 tataaggaga tacctataaa gaaaaaaatg gttaaagtga aaagagatat acgataattt
     2641 agtcaatatt gatgaattgc tttgttatcg aaatgaagtt gcaaaaaaca caatagaagt
     2701 tgttaaggat ttgaaagctg aagatatgaa acgaaaggtc tctccaattg acttagaaag
     2761 gattttggtg actggaggag taataaagca tgaagattct atttggttgt tggacttttg
     2821 ggggaataaa gatattgctg gaattttgct tatgcctcct actcgtcatg ttatacttca
     2881 tttgaatgat tgttgtaaat ggaaggaata ttttcgtaca aaaaagaaat tttacagaag
     2941 ttaaattata ataaattaga caaacaatag ataaattagc aaggaatgtt gattttatct
     3001 acattctaag ttatactatt tttaagtggc taatggaata gtcattttaa atataagtaa
     3061 taaatatata cctataggga tattaaaggg gggaaatata tggcatattt taactataac
     3121 gacaaacagt gctactataa tgaaattggg gatggtacac cattactttt tttacatgga
     3181 aatacagcct cttccaagat gtttaatgat ataatcgatt tttataaaga tgaatataaa
     3241 gtaatattaa ttgattttgt aggtcatgga aaatctcaaa tggtcgataa attttctgct
     3301 gacttatggt ttgatgaggc tatgcaagtg atatgttttt tagaagcaat gaactataaa
     3361 aaagtaaaca taattggtag tagtggagga gctcttgttg cattaaatgt tgcacttgag
     3421 agacctgatt tagtgaataa ggtaattgca gatagttttg aaggagaagt tcctctagag
     3481 tcatttgtac aaaatgtgaa aatagagcgt gaagcatcta agcaagatga tggtgcaaaa
     3541 gctttttata tttataatca aggagaaaac tgggaaaaag ttgtagataa tgatacagaa
     3601 gctatttttg aacattataa aactatagga aaattttttc ataagcctct agaaactatg
     3661 caaccagagg tgcttttaac aggaagtaga gaagatgagt ttgtatctct aatatctagt
     3721 gatttttttg aaaatacttt ttcattactt cttgaaaaga ttaaaaatgg taaaatgtat
     3781 ttgtttgata aaggtggtca tcctgcaatt ttatcgaatg gattagattt ttcaaatgta
     3841 gcaaagaaat ttttagagga ataatttaac caaaatttat aataatgaaa actgtaaaat
     3901 ggattgcaaa acttacaaaa gtgagtgtac atatacttca ttattatgat gaaatagtat
     3961 tgttaaaaca aaatattcta atagtcaagt tattacattt gtatatgcaa tatgtataga
     4021 aagagatatc attagattgt aaagttggga ttaaataaca atattaaatt ttatttattc
     4081 agatatttta gcttaactat ataaatgtta gaacaaattt atatagttaa gctgtaggat
     4141 taaataattt agttaaataa gtttattatc tcctcatcag atagactttt taatacacct
     4201 tcattagaaa gttctccatt tataaattga tttataagct cttttttact ttcttgtaat
     4261 tttattattt tttcttctat agtcccttta gcaatcaatt ttataacttg tactgaattt
     4321 ttttgaccaa atctatgagc tctatcacta gcttgatttt ctactgatgg attccaccat
     4381 gggtcaaagt gaattaccat gtcagcagat gtaagattta aaccagttcc gcctgctttt
     4441 aaagatatta aaaaaacttt tttatccata ctattattga actcatctac aagttcaagt
     4501 ctttctttgg cattagtttt accatctata taatggtatt taattttata cttatcaagt
     4561 tccttactta tgttcttaag cacagaagta aattgtgaaa acaataatat tttgtggttt
     4621 tcgtttatac tatccctaag tatttctaaa catgtttcaa tttttgaact ttttttattg
     4681 taatctttta ctactatact tgggtctaaa caaagttgtc ttagtttagt taaataagaa
     4741 aatataacta ttttatcttt ctttagattt ttatctttca ttttatcttg tatatctttt
     4801 gaatatacac tatatatctt tttctgctct ttattcaatt caacaaaaaa gtttttttca
     4861 atcttatctg gaagttcttt cataacttgt tttttacttc ttctaagaat aaaaggtttt
     4921 atcaattttt tcaggttttt aacattatct tctttattta taaacaattc ctgaaacttt
     4981 gctttactat atagatagcc aggcattata aaatcaaata tagaccataa ttctagtaga
     5041 ttattttcca taggtgtacc agtgagtgca aatttatttt ctgcatttat actttttaca
     5101 gactcagtta ctaaagctac tggatttttt atattttgag cttcatctaa tatacaataa
     5161 tcaaacttta tttcactata tttttctaaa tcatttctaa gagtaccata tgttgtaagt
     5221 attacatcaa aattttctaa ttccataaaa catttttctc tatctctttt atttccatgt
     5281 atcaataaaa cttttatatc tggagcaaac ttttcaaatt catttttcca attataaatg
     5341 agtgatgtcg gtgtaacaat aagacttttt ttattagata atgataataa aaatgcaata
     5401 gtctgtattg ttttaccaag acccatttca tcagctaata taccaccaaa tttataataa
     5461 tctaaaactt taaaccaatt gaggccattt atttgatagt cacgaaggtt tgcatttaaa
     5521 tttgcgggaa tttctaaatt tatgctatca aaatttctaa atttttcaca tatactgtct
     5581 agttcttttt taccatctat aaactttaaa tttttactac gtattacatc atttatatat
     5641 agagctttat ttttatgaat tttattattt tttgatttat ccattatatc tagattttca
     5701 actaattcaa aaaaatcttt tgtttctctt tctgataaat ctataaagtt tccatcttta
     5761 agtttataaa aagtacgttt ttcttgaaaa gctttcaaaa tatccttgta ctctcttgga
     5821 tttatatcag atatattaaa attaaattct aggtaattct ggttagtctg attgattgaa
     5881 gcttgaattg atgaagcgtt atatattttt ttcaatttaa acttctcaga ataatatata
     5941 tctccaaatt cctttagaga ttctaattgt aaatctaaaa atgtaaatag gtcatggtca
     6001 gttcctttaa acacataatg attattttcc tttgtaaatt gtgaagaagt aagtttattt
     6061 tcaatagtag cttccttttg tatgttgggg agcacaaatt ttttatcttc atcatcatat
     6121 atatacttta catcacaaca tatgttgcca tcaatcatat caaagtagaa ctcagattta
     6181 aaatcttttg ttatattatt ttttatgtta tcatctaaat gaacttcttg agatatagat
     6241 tttaatctag gaactagcaa tcctaaaaca tccttagaat cctctttatc aaattttaac
     6301 tctttagtct ttgataatat ttgatatatt tttgaataat catgagcttt tttatgtgat
     6361 aataaataga tattgccatc atataaaagt acatcatttt ttttagtaag tggaacaggt
     6421 agtgaatctt tagaatataa gactatttta tcttctatat ttttaaaatc aaaccttaca
     6481 ggtagagtat catttaatat ctttggatga tattcctctt tagaaaaaat aagggtaaaa
     6541 tccttgtact taatagcatt taaaaattgt tttaaagagc ttgcatttat ctccataaat
     6601 ttttttgaat gtgatgaaga aaagttgtat gaaagatttg tcccatattc ttctataata
     6661 tctactaact tctcatcttc atcagcaaaa taatgagtgt tggggttgta agtaaatttc
     6721 ttcccaaaat ctaattcata tccattaagt tttgaatatg caaattcagt aatgtttttt
     6781 aaaatgtaca ttttatcaat tcctatttta aattcagcaa ttgctttatt tgaatccaca
     6841 tttatcaata catctaaatt aaccctttct cttttagtat tgtctaacaa agaaagtaat
     6901 tgcttgctta aatctaagct ggttttagaa tttgtattag aaagcttatc cttatctgca
     6961 cctaatatat ctattagaat aggaggaaca tcttttttat tttttatttg ttttaagctt
     7021 tttatcacaa tagcaactat atgcttacat ataaaaatac ttttgccctt tgattgacag
     7081 tcagcgcaac tacaatcatt ttcaattatc ttaaagtgct ttatatctat agttattgaa
     7141 ttaaaataaa agctataatt atcttcagaa ttgactccac cacgaaatgt caacaggtta
     7201 ttttgtaggt catcaatatc tatgtctata taatcaacta attgattagt ataatatttt
     7261 acacctcttg accatcttga tggttctgta tttcttctta ttagtttata tatcatatct
     7321 attttcatat tattcacctt acctcactgt atatattata atctaaatgc attcaattta
     7381 cactctaaat ttaagactaa aattaaggca gatatgaata gcttttatct atcacaatat
     7441 atgtgtaaat aacaatttac tattagattt ttattgaatt atcttataaa ctatgaatga
     7501 aaaataatta tataaataga ttattaataa atataaaatc ttattattaa aaatattctt
     7561 agaaattaca ctatataaaa tataaagtat gatatttgaa taaaaagaat gtataataag
     7621 tataataatt tgtatttatt attgggaaag gaaaatgtta atatggatag ttatagacaa
     7681 cttaaagcta aaataccctg taaggaaaca ggtatagaaa taaagaggac tttatgtgat
     7741 atttgttctc caggagtaca ttgtggaatt gatgcatatg ttaaagatgg taaagtaata
     7801 aaaatagaag gtacaaaaga acatccaatg aataaagggt tgttatgtac caaaggtctt
     7861 tgcaatagag aatatatcta tagagaagat agaataaaaa cacctctaaa aagaattgga
     7921 aaaagaggtg aaggaaaatt taaaccaata tcatgggatg aagcttatag agaaatagca
     7981 gaaaaattaa atagagtaaa atctgagtat ggagcaaagc atgtagcttt ttttacgggt
     8041 tatggaaagt ggtatagacc ttttttacaa aggtttgcat cttcatttgg ttcacctaat
     8101 tatggtacag aatctagttc atgttcaaca tcagcacaga tggctggaaa tgttgctact
     8161 ggaagaaact ttacaatgca agatatggag aatgcaaaaa cttatttagg gtggggattt
     8221 aatccatact actctaaatt tttaaatagt gtgaatctaa taaaattaaa agaaaaaggt
     8281 ctaaaattta taattgtaga ccctagaata acaccgacaa ctcaaaaact agcagattta
     8341 catttaagaa ttaaacctgg aactgatgga gctttagctc ttggaatggc gaatctattt
     8401 atacaaaagg atttaataga tagagaatac atagaaaagc atgtacatgg atttaatgaa
     8461 tataaagaat atgtaaaatt atttgattta gatactgtaa gtagaattac aggagtttct
     8521 aaagataata tagtaaaagc tgtcgagatg ttgtcacaag gtccattttg tataaatgaa
     8581 agtgcagctc caatagttca ccatcaaaat ggatttcaaa attatagagc aatgatgtct
     8641 ttatccgcta taacaggtaa ttatgataga ataggtggaa acataccaaa acaagattac
     8701 tttgctggta agataggtgg attccaaaca ctagaaaaag agtttgtaaa agaagttcta
     8761 cctaaaaata taaatgaaag aattggtgga gaaagatttc ctctatggaa tgaaatggtg
     8821 actcaatttc aagctatgga tttacctagg caaatagaag aaaagacacc atatgaaata
     8881 agagctttgt tttgtcatgg gataaatgct agaatgttta ctaattcagg gagacttttt
     8941 aaagcgttga atagtgtaga tttttttgtg aatatagatt tatttatgac agatacatca
     9001 aaatatgcag atatactttt acctgcatgt acatcatttg agagagaaga atgtaagagt
     9061 tatccaggag ggtatattac atataccaaa aaagttattg ataaattata cgattcaaaa
     9121 tcagatgtag aaatactttc agatttagca aatgctatga atatagatga tgatttatta
     9181 aaagcaggtt atgaagcaag tataagacat atgtttaaaa atacatgtgt agatgtagat
     9241 aaacttaaag aaagtgattt accattaaaa tgtaaagatt ttaagccata tatagtaggt
     9301 tcatatacaa gagaagggta tgatactagc acttctaggt ttgaattaaa atctacaatt
     9361 attgaaaaat ataaagattt tgggctggat gcactaccaa catatagagg atttaatgat
     9421 aatatagatg atgaatatac tcatttattg acatcaggag caagaatttc aaatgcacta
     9481 cattcaagac ttcatgacat caaactttca agaatattaa aaaatgaagc tagttgtgat
     9541 atttctagct tagatgcaaa agaattgggt gttatcagtg gagattatat aaaaataact
     9601 actaagatag gaagtttgga tgtaaaagtc aatgttactg atagagtctt atataagaat
     9661 atacatatgt atcatggata tagagaagct gatataaata gtattatttg tgataatttt
     9721 gacccttata gtggattccc tgcgtataga agttgtaagt gtaagattga aaaaatgaat
     9781 agataaatgg agagatataa tgaaaagttt atttaaattt aataaagaat tatgtacagc
     9841 atgtggagca tgtttgcttg catgtataga ccaaaatgat aataatatag acaatggtga
     9901 actttttaga catgtattta caatagagga aggtgaaaat atagaatatt tttcattagc
     9961 atgtatacat tgtaatgagc caaaatgttt aggtgtatgt cctaaaaatt gttttaaaaa
    10021 agaagaagga ttcattgtat tagacaatca aaactgtata gggtgtaaac tttgtgaaaa
    10081 agcttgtgaa tatggagcct taatttatgg aaatgatggt aaggcaaata agtgtaatgg
    10141 ttgtattgag agatataagt gtggtatgga ttcaccttgt gtaatggtat gtcctacagg
    10201 agcattaaaa tttaataaat aaattaaata tagagaatga cttatactta ggtataagat
    10261 atttttacaa aaagctgtat tgagtttgtt ataatgaaaa ctcaatatag cttttttatg
    10321 gatatagttg gatactataa tgtgattctt agtaatagtt ttttgctatt ggacaaagac
    10381 tgtaaaacat attaaactta tgttgttcaa agtcgaagta taatataata actagaaaat
    10441 tggtttatag tgctataaaa gcaaatttag taaggtataa aatcagaggc aatcctttac
    10501 tataatatca atatttggga gttctgttat tgcagagcta ttaaacaatt ataatggtac
    10561 aagtgattca acctttgaaa atgtattata taaaaaatta aaataagatt aaaaaggaga
    10621 gaataaatta tgaaaaaact taaattaatt attatgtttg ccttggtatc agcactgtta
    10681 gttacaggat gttcatcagg aaataataaa aataaagaag aacaaaaagt tataagagtt
    10741 gcaacatcag gaacatatta cccttttgct tttaaagata aagataaact taaagggttt
    10801 gaagtagatt tttgggatga atttgctaaa cgaactaatt gtaaagttga atgggtatta
    10861 actgatttta gtggattatt tggattatta gaagctgata aagcagatgt tgtatctgct
    10921 caacttactg caacacctga aagagagaaa aaatatgctt tttcagatgc ttataattat
    10981 agtggaacaa acattattgt tagagaagat gatactagta taaaatcaat agatgattta
    11041 gttggcaaga aagtaggtgt gggtactgga gcagtagcaa atgaaatatt aaaagaaaaa
    11101 tacccaaatg atgaaataaa aatagtaaat tattcaagtg cgactcttaa agggaattat
    11161 caagacctag aaatgggaag attagatgca gtagttgcgc aggatgttga ggctttaata
    11221 gctataaaag aacaaaaatt aaatcttaaa atgatagaac ctccaattca atttggtgcc
    11281 tgttcttttg cgcttcaaaa aaatgaaaaa ggtgaaaaat ggacaaaaga aattaacgaa
    11341 gtaattgaag agatgtataa agatgggact ttgactaaaa tatctgaaaa ctggctagga
    11401 aaagacatta ctaaggagcc tattaatgag taattttaat tttgaatttt gtctaagtat
    11461 atttccattt ttgattaaag cattgggaat aacaatacta atatctattg ttgcattttt
    11521 tttatcaata ttattaggtg taatacttgc ctttttcaca cagacaaaat caaaagtttt
    11581 acaatacata acaagagtgt atgtttcatt ctttagagga acaccacttt taattcaaat
    11641 atttttcttt tattttggat ttccaatgat attttctttt atgaaagatt gttcacctta
    11701 tttagcaata gtaatttgtt taggtgtaaa ttcatctgca tatatggctg aaattatacg
    11761 agcatctatt gagagtgttg ataaaggaca acaggaagca tgttatgctt ttgggttaag
    11821 taaatatcag tcaatggtta aaataattct acctcaagca gctacatctg cagtacctcc
    11881 tattgtaagc tgtacactgg acataattaa aggttcttct ttaggtttaa ctataggaat
    11941 acaagattta atgggagtag ctcaagtaga ggctgcttca agttttaaat attttgagat
    12001 atatatgata acgatattaa tttactgggc agtatctata atattgagta atatacaaag
    12061 caaagttgaa aaaagaataa gaagagcata ttagatttca atatttaaaa atgggatgat
    12121 atagatatat tattacttgt aaataaattt ttaattttag aaaaataaac ttagtaatct
    12181 aaattattga gaaaatatag tatcaaaatg gactgtataa tcaagttaaa aaatagtttt
    12241 tctattgaaa aaataaataa aattctattg taatttaata tgcgataaag ttttataaaa
    12301 aacaacatta agctaggggg acttatttta tggcttttaa tatgaaatat tttttagaat
    12361 tatttccaac aataatgaaa tcgttcaatg taactgtgat tttggcaata agttcattag
    12421 tattttcatt aattataggt acaatagtag cgttatcatc ttattacaaa gtgaaagtat
    12481 tgaatcaaat atgtaaagta tatgtatcta tttttagagg tacacctctt atgccacagt
    12541 tattcttttt atattttgga ctagcatata tgagtgattt tgttaaaaat atggacccag
    12601 tatttgcaac atctatagta cttagtttaa atatgggagc ttatatgtct gaaacgataa
    12661 gggcatctat actttcaatt gatacaggtc agatagaagc agcatatgca atgggattaa
    12721 caaatttaca aacaatgaaa aggatagtga taccacaggc cgtaagagtt gcactgccat
    12781 cattattcaa taattttata gatttaatta aagggtcttc tgtagctttt gttgttggag
    12841 taaatgatat aatgggtgct gccaaatcac aaggagcgtt gagttttaag ttttttgaag
    12901 tgtatggagc agttatggta atttactggt gtataataac tcctttaggt tgggggcaaa
    12961 aaaaattaga aaagaaaata agcaattatt aagttattaa gaaaatacat aaaagtattt
    13021 ttatataaaa aatggtgtga ggagaagaga tatgataaaa agaaatatta taaaatgttt
    13081 agtggcagtt ttatcgttaa cgtttgtaat tactggttgt tcaaaaaaag aggaagtaaa
    13141 gaatgaaaaa gttataactg tagcttcatc taattcagct gacccatatt cttatgttga
    13201 taatggtgag cataagggtt ttgaagttga catgtggaaa gagattggta aaagaagtgg
    13261 atataagata aaaatggaac caacaggttt tagttctata tttggtatgt tagattctgg
    13321 taaagttgat gtggcagcca acttctttgg aatgtctaaa gaaagattag aaaaatacga
    13381 tgcttctata ccttatggtt ctgattctgt gtgtatagct gtaaaagatg gaaataacga
    13441 aattaataag cttgaagatt taaagggaaa agttgtagca gtttcagaag gttctcaagg
    13501 tcaacaggtt gcaactagtg ttaataaaga taatttgttt caagaaaagg tttacggtga
    13561 tggaactagt ggtcttcaag atttagattt gggaagagtt agtgcatgga ttgatgcaga
    13621 gcttactatt gtgggagacg ctaaaaaagc taatatgaaa gtaagagtat tagataaaaa
    13681 attatcagct actaatatag catacttctt taagaaaaac gatgataaat ctaaaacgat
    13741 aaaagaagat gtaaacaaag caatagaaga aatgcttgca gatggaacag tgaaaaaaat
    13801 atctgaaaaa tggtttggaa tggatgtaag tgctgatata caaaaataaa tactttaaaa
    13861 ttaaaatgta aaactgtgat aactatagat aagtatacta aatttatcta tagttatctg
    13921 tgtattacaa tgtatttaga ttagtcttta taaatcaaaa tgagttatgg aggtattgca
    13981 aatgattgaa actaaaataa aatccattgc actaaaaaat agagaaaaaa ttataaaaat
    14041 aagacgacag atacacagta atccagagtt agcatttaaa gaatataaaa catctaaact
    14101 tataaaagaa gagctaaata aacttaatat agaatacata aatattgctg gtacaggagt
    14161 attagctact ataaaaggaa aaaataatgg tggaaaaact atattactca gagcggatat
    14221 ggatgctctt ccaatcaaag aggaaaatga tttagaattt aaatcaataa atgataatat
    14281 gcatgcttgt gggcatgatg cacatgtttc atggttgtta ggaacagcaa tgattttaaa
    14341 tgacataaaa gaagaattga atggaaatgt aaaattacta tttcaacctg gcgaagaaaa
    14401 aggtggttct gatattgtaa ttaaagaaaa tgtacttgaa ggtgtggatg cattagcgac
    14461 tggtcattgt tggccaacta ttgagtcagg aaaaattgga atcgctagaa attgtgctat
    14521 ggcagcgact aatacttttg aaataacaat aattggcaag ggtgggcatg gagcagagcc
    14581 tcataattgt atagacccaa ttgcagttgg aaatgcagta tattcatcca ttcaacagat
    14641 agtttcaaga aaaattgacc cagttgtacc tgtagtagtg tctgtttgtt cttttaattc
    14701 tggtgtttct aaaaatataa taccagatgt atgtacactt caagggacta ttagagcgat
    14761 aagcaaggaa caagtaattg aagtaagtaa aattctagaa tatatagtaa aaaatgtatg
    14821 taaagcacat ggagcagatt gcaaatttga aaagagtaca ggaggagatg ctgttataaa
    14881 tgacaaaaac atgatagaga taggaagaga aagtgcttgc aaaatacttg gagctgaaaa
    14941 tgttgaaata attgattttc ctgcaatgac aggtgaggat tttgctattt atatgaaaga
    15001 aaaacctggt ttatttatgt atataggtgt aggagataaa gaaaaaaata taaattacag
    15061 attgcatagt aacaagttta atatagatga aaaatgtctt agtatagcac cttcattatt
    15121 ttcacaactt acagtagatt atttatgtca actatagagt acattcataa aaatatattt
    15181 agcctatttt taaatttaat gctagtatat taattttgat gtagaacata ttatttatta
    15241 tatttattta aaaaggtgga taacaatgat aaaagtagaa aatttacata aaagttttaa
    15301 agggacagaa gttcttaaag gtataaattt agagataagt caaagtgaag tagtagctat
    15361 acttggatca tctggaacag gtaaatctac gttacttaga tgtttaaatt atttagttga
    15421 gcctacaaaa ggaaagataa tgattggtga tgtaaaagta gatgtagaaa aagcaacaaa
    15481 aaaagatata accaatttaa gaaaacatac atctatggtg tttcaaaatt ataacttatt
    15541 taaaaataaa acagcattag aaaatgtaat ggaggcattg atagtagttc ataaaaagag
    15601 taagaaagaa gctagagaaa tatctttaaa attaatagat aaagtaggta tgttggatag
    15661 gaaagatttt tatccatcaa agttgtctgg gggacagcaa caaaggatag gtatagcgag
    15721 agcgatggca gtaaatccaa atgtaatatt atttgatgag cctacatctg cacttgaccc
    15781 agaacttgtt ggagaagttt taagcgttat aaaatctctt gcaaaagaag gtataacgat
    15841 gcttattgta actcacgaaa taaattttgc aaaagaagtt gctgataaaa ttatatttat
    15901 ggataatggt gtaatagctg aagaaggaac tcctgatgaa atatttaata atcctaaaaa
    15961 tgaaagaaca gcaaaatttt taaatatcat taggaaagaa gaagtattta gttaaaagtg
    16021 tataaattaa gcattagaag atatgtaaga tacccccatt aaatttataa gttagataat
    16081 aaatttaatg ggagtatatt tttattatta gatttattat ttaatttaaa attagaaatg
    16141 taactatttg aaaattcttt ttaaaagtat atcaaaatat caaatacata aaaaaataat
    16201 atttgacaaa gtatcatatg tg
//
LOCUS       DAEPKC010000092        15666 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.092, whole genome shotgun sequence.
ACCESSION   DAEPKC010000092 DAEPKC010000000
VERSION     DAEPKC010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15666)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15666)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15666
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.092"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            982..1743
                     /locus_tag="KR294_002936"
     CDS             982..1743
                     /locus_tag="KR294_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896901.1"
                     /note="N-terminal region resembles flavodoxins. C-terminal
                     ferrodoxin region binds two 4Fe-4S clusters; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EFR1 family ferrodoxin"
                     /protein_id="HBH0240998.1"
                     /translation="MIGIYFSGTGNSRYCVEKFLQEYDITANSYSIEDNELLQHINNH
                     ENIIFSYPVQYSNVPKILKDFIINHSTLWNGKRVFIIATMALFSGDGSGVLSRILKKY
                     GAITVGGLHVKMPDSIGDEKVLKHSLEYNRKLVIKAEKKVTKAAKKLKHGSPPKEGLG
                     FLSHIVGLFGQRLYFINKTNMYTDKLKINTEECIVCGKCVNLCPMKNLVIKNCMIVAN
                     GQCTMCYRCVNNCAKKAITLLGKKVVEQSNIKKYM"
     gene            1808..2590
                     /locus_tag="KR294_002937"
     CDS             1808..2590
                     /locus_tag="KR294_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HBH0240999.1"
                     /translation="MEYYIVDSFATKLFKGNPAGVCVLDRRIPLELMQKIAEENNLPE
                     TAFVVKGKGNYELRWFTPKAEIDLCGHATLAAAYVISNFIDVNVKRIDFFTQSGKLEV
                     TRNGNLYEMIFPEIMPIEIELSPQQANLIGCVPSAVYSSRDLILLLNSEQEVINYKPN
                     YAQLRKLTDWLGIIITAQGSNTDFVSRYFCPELDSEDPVTGSSHCNLIPYWSEKLGKH
                     KMVAAQLSNRGGIIQCEVLKDNTVKISGEAVLFMQGTIKIDI"
     gene            2857..3276
                     /locus_tag="KR294_002938"
     CDS             2857..3276
                     /locus_tag="KR294_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjdF family protein"
                     /protein_id="HBH0241000.1"
                     /translation="MDKISGKLTVLFEEPFWVGIFERQDGKKYEACRVVFGAEPKEVE
                     VYEFILERFFSLDFGSIKLEKNVTKDNIGYKRMQRKVKKEQEKETIGTKAQNALKLQY
                     EERKQDRKNLAKNRKEEEKERLFNLKQEKRKAKHKGH"
     gene            complement(3379..3645)
                     /locus_tag="KR294_002939"
     CDS             complement(3379..3645)
                     /locus_tag="KR294_002939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HBH0241001.1"
                     /translation="MKNFILIYFIVINSIAFFSMYIDKKRAIRNEWRIKEATLMSIAV
                     IGGSIGSIIGMYSFRHKTKHIKFTFGIPFILFLQFLLVYFYILK"
     gene            3872..4573
                     /locus_tag="KR294_002940"
     CDS             3872..4573
                     /locus_tag="KR294_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241002.1"
                     /translation="MKFIVEKEVFDKLENVCFGVVVAKGIDNTKEIERISNLLDISID
                     RVEDYFKDKKVKESEEIIPYREAFRSLGMNPNKFMSSIEAMTTRVAKNKKLPHINPIV
                     DLGNSISLKYLLPMGAHDMDFRNDDVYVRFSKKGDKFVPFGETDVELMEEGELIYSVG
                     DMVKTRRWIWRQGEEGKITNSSKNIFFPIDGFTDANLDKVMSAREELAKLLKEIFNCE
                     IKVGFVDKDNPEMEI"
     gene            4655..5263
                     /locus_tag="KR294_002941"
     CDS             4655..5263
                     /locus_tag="KR294_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBH0241003.1"
                     /translation="MKKTIIKNVNPMIENKFIGLFEIEYKNKLDEDKVWMVASRKSSE
                     QLKNIYLKNEEDSVDAVVIVGLHKSSKKLILIRQFRVPINGYIYELPAGLVDEGESID
                     ISVERELREETGLTLLEIKKNKSIDKVYLSPGMSDESVAFVYCICDGDITDEFLEPDE
                     EIEALLISQEDAKEILQSNHKIDTKAFLILQMFVSLGAKLFE"
     gene            5587..6051
                     /locus_tag="KR294_002942"
     CDS             5587..6051
                     /locus_tag="KR294_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4624 domain-containing lipoprotein"
                     /protein_id="HBH0241004.1"
                     /translation="MKKLVIILISIISMVSLTACKKSNESKYNNLNNKESGQTTIEMD
                     LDKNYDTSDPFVNARLFCVSNDIDVLDTEISFKMDGDSGIVEIKDNKTDETLWSNTWH
                     GSVDNDTFTISLSNIQKEKEYAICFTGIKINHAVVKVTFESNLVKEKEKPSK"
     gene            6688..7704
                     /gene="gap"
                     /locus_tag="KR294_002943"
     CDS             6688..7704
                     /gene="gap"
                     /locus_tag="KR294_002943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011948756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HBH0241005.1"
                     /translation="MKIKVGMNGFGRIGRAVLRIAQEELGDNIEIVAINARATTESLA
                     HLFTYDSCYGTFRGEVEAKDEDTLVVNSKEIKILRYNDPEELPWKELGVDIVIESTGL
                     FTQREKAEKHIKAGAKKVIITAPGKNEDITIVIGVNEKEYDNEKHNIISNASCTTNCL
                     APFAKVLDEKFGIVKGLMTTVHSYTNDQRILDKSHKDLRRARAAAESIIPTTTGAAKA
                     VSRVLPQLEGKLNGFSLRVPTPTVSLVDLVCELKENVTSEQVNSVLKDAAEGELKGVL
                     GYCDKPLVSIDYKGDSRSSIIDALSTMVIEDNMVKVVSWYDNEWGYSSRTVDLVKYVA
                     EKLK"
     gene            8099..9268
                     /locus_tag="KR294_002944"
     CDS             8099..9268
                     /locus_tag="KR294_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241006.1"
                     /translation="MEKLTDRRQVKAVSMETFIFLILLVVGFGYVGSIMGAGMMFKVI
                     MSTAHALLLETVFLIMAMAVLAGALSALLSEFGVIALINKIFAVFMKPLYGLPGASIA
                     GAITTYLSDNPAIIPFAKDKTFTQYFKQYQVPALCNLGTAFGMGLILTTFMISQGTEY
                     VLPALIGNLGAIIGSVISVRIMLTFTKKFYKYNPEEDKATGTLEKKDEFREIREGNVF
                     QRALDAILEGGKMGVDMGMAIIPGVLVVCTLVMLLTFGPSTDPVTGQEVYTGAAYEGI
                     KLLPVIGDKLGFILEPLFGFTSPEAIAFPITSLGAVGAAMSLVPEFIKSGAITPNDIA
                     VFTAMGMCWSGYLSTHIGMMDALNARQLAGKAILSHTIGGLCAGAAAHFIFTLVG"
     gene            9648..13901
                     /locus_tag="KR294_002945"
     CDS             9648..13901
                     /locus_tag="KR294_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyacyl-CoA dehydratase"
                     /protein_id="HBH0241007.1"
                     /translation="MDELFHIGIDVGSTTVKVVVLNNSNNIVHKEYRRHYSDVKKSVK
                     EVLNGIYEKLGDINTTIIITGSGGIGISKKLGVKFVQEVISSTKSIEYFHPETDVVIE
                     LGGEDAKITYLSGGIDQRMNGICAGGTGAFIDQMASLLKTDASGLNELAKGYNVIYPI
                     ASRCGVFAKTDIQPLINDGANQTDIAMSIFNAVVVQTVSVLSCGRKIEGNVAFLGGPL
                     YFLSELREAFKRVLDLKDENIIFPENAQLYIAIGAGLLSVDEDNIQLKSLIEKLDSIK
                     NIEDGEVNLLEPLFKDKNEYEEFSRRHEKEKINYVDINSIKSNCYLGIDAGSTTTKAA
                     LIDEDGRLVYSYYNSNEGNPLKTTIKVINEVYDILPKNIKILSSTVTGYGEGLIKKAL
                     KIDNGEIETIAHYKAAKFFNKDVDFILDIGGQDMKCLKIKDGVIDNIILNEACSSGCG
                     SFLETFASSLSMTIEEFAHEGIYSQNPVDLGSRCTVFMNSRVKQAQKEGASVGDISAG
                     LSYSVIKNALFKVIKIRDLNEIGNNIVVQGGTFYNDLVLRSFEKLIGKNVIRPNISGI
                     MGAFGSALIAKEKYESGYKTSLLSKEELNNIKLEASVTRCKGCSNHCLLTINKFSDNE
                     IFISGNRCEKGEAIYGDKKIGLEKKKPINLFKYKYNRIFRYKPLEKEEAKNGEIGIPR
                     VLNMYEDYPFWFTFFNAMGFRVVLSDRSSKQLYETGITSIASETVCYPGKLVHGHIEN
                     LIAKGIKNIFYPSVTNENKEDSNADNYYNCPVVISYSEVIKNNVENIRNKNINYINPF
                     ISLNDKEKLKKRLYDELSRHFSDIKITKEEVNHAVDKATDEQNLFKMEIQAAGERALK
                     EIKERNMKGIVLCGRPYHIDPEINHGMPELINSLDMAVLTEDSICHLANVQRPLRVVD
                     QWVYHSRLYKAASFVRDKNYLELVQLNSFGCGLDAVTTDQVQEILNEKSKIYTIIKID
                     EGNNLGAAKIRMRSLKAAMFERESKNIDVKNIKVNRIQYAKNNQITNKHTILAPQMSP
                     IHFQFLEKAVNLSGYNIEILKDTDSSVIEEGLRYVNNDACYPAIIVVGQLITALKSGK
                     YDLNNTSVTITQTGGGCRATNYIGFLRKAIYDAGFKDIPVIALSVNGIEDSGIMDNIS
                     LKLINRLFMSVVYGDLLMKVLYRVRPYEKVTGSANALYEKWVDICKSSLVKAKISVFT
                     RNIKDIVKEFDNLEILDIKKPKVGLVGEILVKFHPIANNNLVDILEREGAEAVVPDLT
                     NFFLSCAFNTIYKHTHLEGSRKSRMIGEAFIYITGIYQRVYKKALDKSERFYAPANIK
                     NVAKSTEPVVSLGNQTGEGWLLTGEMVELLNEGVENIICMQPFGCLPNHIIGKGSIKE
                     LKRLYKNANIIPIDYDPSASEVNQLNRIKLMLSKAFKNI"
     gene            14050..14544
                     /locus_tag="KR294_002946"
     CDS             14050..14544
                     /locus_tag="KR294_002946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HBH0241008.1"
                     /translation="MSLVYDVYKSKLGNLYILSEDGFIVSIYIGDEKFNNLKNECIKK
                     GIDIKRSKEDLKEAISQIDDYFNGKRKVFNLNIRIEGTEFQKSVYREMLKIPYGETLC
                     YSDIARNINNPKSVRAIGQASKSNKIPIIIPCHRVVGKKDIGGYMGNHSDLKEILLNL
                     ERQS"
     gene            14660..15037
                     /locus_tag="KR294_002947"
     CDS             14660..15037
                     /locus_tag="KR294_002947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="monooxygenase"
                     /protein_id="HBH0241009.1"
                     /translation="MCDKVIASKYHEKGFNCAESVIKAYNEEFNTDIPVCLGSGLGSG
                     CGVASLCGAVNASNIIIGYVKGRNHEDESTKAKVYAKDLTTTVRKEYGSELCIDLKKD
                     LVACREIMDFAYDSLKETLKKEL"
     gene            15243..>15666
                     /locus_tag="KR294_002948"
     CDS             15243..>15666
                     /locus_tag="KR294_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SufBD protein"
                     /protein_id="HBH0241010.1"
                     /translation="MKNLNLLINKLYSKNHNEAYKTFLFLENESLKSNITYCFFDSFL
                     EMIDNENSYIRTRGLLLISANAQWDIDNKIEINIDSILSHIVDKKPSVSRMFIKSIPN
                     ITKYKENLINRIKMELSNADISIYNNNMKPLVEKDINDT"
BASE COUNT         6389 a         1539 c         2735 g         5003 t
ORIGIN      
        1 tacatattga aaaatggaaa cttttatgtt atttttagta cattacaaat ttgcttatat
       61 aaaaatcaat acttgaatta ttatttttat gtgaaattta tctatagtat atttttataa
      121 acaagtaatg ttattaaaat taagtatgta gttaaaagtg tatagcaaaa aggctgttat
      181 attaatgtta gaggttcagg gaaaatatat aaagcaaagt atttacagat aatgtagatt
      241 gcacagctat aagttagata atagaattat gtaatcaaga atttacaaca aagtataaga
      301 taaggataat gctaaattgc catacaggtg ctagatgtgt aaatggattt aattaatact
      361 attgataaag tgcaacaagc acataaacca attgatgaga ttattaaaac tataagagat
      421 atagttgaca taattaaaat attggaactt gtttataatt ttaaatcaaa tcaataatga
      481 ttaagattaa aataatatta aggcatcaat gttataagag tacaatataa ggagtactat
      541 atagtactcc ttacttatac atattaggca ataggaaatt ttttcatagt taaattttca
      601 agtatttttt aggaaacttt ataattgaga attaagggta tagtatgtga tgaacttact
      661 gaatttataa ttaggttata taatggaata atcatcaata gttttacttt agggaaaata
      721 tatgcttaag gaagtatagc ttactaatat tattaaaatg tatatttaaa atgataaaaa
      781 aagaattaga caagtattta gtaaattgac tatgcaaaat tctatcaagc aggaacccta
      841 tgactttagt catgggaggt tcagtaggta acttgttgaa ttaagtttat attatttaaa
      901 taaactactt aatttagata atataaaaag tcagaatttt aagaatagag ctatataatc
      961 ttagctatta ggagaattac tatgatagga atatatttta gtggaacagg aaattcaaga
     1021 tactgtgtag aaaaattttt acaagaatat gatataacag caaattctta ttctattgaa
     1081 gataatgaac ttttacagca catcaataat catgagaata ttatttttag ttatccggtg
     1141 caatatagta atgtgccaaa aatattgaaa gattttataa taaatcattc aactttgtgg
     1201 aatggtaaac gtgtttttat tattgcaact atggctctat ttagtggaga tggctctggt
     1261 gtgttatcta gaatattaaa aaaatacggt gctataactg ttggtggatt acatgtgaag
     1321 atgccagata gtataggaga tgaaaaggta ttaaaacatt ctttagagta taatagaaag
     1381 cttgtaataa aagcagaaaa gaaagtaact aaagctgcta aaaaactgaa acatgggtca
     1441 ccaccaaaag aagggttagg ttttttgagt catattgtag ggttatttgg acaacgattg
     1501 tattttatca acaaaacaaa tatgtataca gataaactaa aaattaatac tgaggaatgt
     1561 attgtatgtg gtaaatgtgt taatttatgt ccaatgaaga atctagtaat taaaaattgt
     1621 atgattgttg caaatgggca atgtacaatg tgttatcgtt gtgtaaataa ttgtgctaaa
     1681 aaagcaatta cattgttagg taaaaaagtt gttgaacaga gtaatattaa aaaatatatg
     1741 taagaaattt aaagttttat tgaatgtaaa ttgatgtata ttttatgtta gaaagagagg
     1801 ttaaataatg gaatactaca tagttgattc atttgcaact aaactattta aaggaaatcc
     1861 tgctggagtt tgtgttcttg acagaagaat acctttagag ttaatgcaga aaatagcaga
     1921 agaaaacaat ttaccagaaa cagcatttgt agttaaaggt aaaggaaatt atgaattacg
     1981 atggtttact cctaaagcag aaattgattt atgtggtcat gcaactttag cagcagctta
     2041 tgtaatatca aattttattg atgttaatgt aaaaaggata gatttcttta ctcaaagtgg
     2101 aaagcttgaa gttacacgaa atggaaatct atatgaaatg atatttccag aaataatgcc
     2161 tattgaaata gagttatcac cacaacaagc taatttgata ggctgtgtac caagtgctgt
     2221 ttattcttca agagatttaa tcttattgct aaacagtgaa caagaagtta taaattataa
     2281 acctaattac gcacaattgc gtaaattgac agactggtta ggtataataa tcacagcaca
     2341 aggaagtaat acagattttg tatcaagata tttttgtcca gaattagatt cagaagaccc
     2401 tgttactggt tcatcacatt gtaatcttat tccatactgg tctgaaaagt tgggaaaaca
     2461 caaaatggta gctgctcaac tttctaatcg tggtggtata attcagtgtg aagtgttgaa
     2521 ggataatact gtgaaaattt ctggtgaagc agtcttgttt atgcagggaa caataaagat
     2581 tgatatttaa ataagtataa taactaattt attatgaaaa ataattaatt ttcttagtgt
     2641 taacaataat aaagtagagt taaaaaactt gatttcactt aaatcaatat gatagatgtt
     2701 gatactaaga ttgacaagca tgattaaaaa agataatatt taatctataa agataaaaac
     2761 acagtctggt tggtagtcca gacgcagcaa tagctgtcag taacctgcct ccttggttgt
     2821 ccgttcttta gaaagtaatt taaggaggaa ctagcaatgg acaaaattag tggaaaatta
     2881 acagtcttat ttgaagaacc attttgggta ggtatatttg aaagacaaga tggtaaaaaa
     2941 tatgaagcat gtagggtagt ttttggagca gaacctaaag aagtagaagt gtatgaattt
     3001 atacttgaaa gatttttctc attagatttt ggtagcatta aattagaaaa aaatgtgacc
     3061 aaagacaaca ttggatacaa aagaatgcag agaaaagtaa aaaaggaaca agaaaaagaa
     3121 actataggga ctaaggctca aaatgctctt aagcttcaat atgaagaaag aaaacaggat
     3181 agaaaaaacc tagctaaaaa tagaaaagaa gaagaaaaag aaagactatt taatttgaaa
     3241 caagaaaaga gaaaagctaa acataagggt cattaatttt aattaaatat ctttttaata
     3301 attgctagaa aaaggtgtat aaaattttta attttataca ccttaattta ttgaaaagaa
     3361 taaggtttta tatttcaatt actttaaaat ataaaaatat actaataaaa attgtaaaaa
     3421 tagtataaat ggtataccaa atgtaaattt aatgtgttta gttttatgtc taaaagaata
     3481 cattccaatt atagaaccta tactacctcc aattactgct atagacataa gagtagcttc
     3541 ttttattctc cattcgtttc taattgctct tttcttatct atgtacattg aaaagaaagc
     3601 aatagaatta atcactataa aatatattag aataaaattt ttcacagtct tgcctccata
     3661 aaaatatatt atacattata aaacaagata tttgttttgg aaagttaaat ttgtaattag
     3721 tacatataaa atatttgata agaacaaata taatattaat tggaaaattt aaaaaaatta
     3781 aacaattagc aaataggggg tatatttata agacacaaag tgataaaatc tatttagaaa
     3841 ataatgtaaa ataacaggag gataaagcaa aatgaaattt atagtagaaa aagaagtttt
     3901 tgataaatta gaaaatgtat gctttggtgt agtagttgca aaaggaatag ataatactaa
     3961 agaaatagaa agaataagca accttttaga tataagtata gatagagtag aagattactt
     4021 caaagataaa aaagtaaagg aatcagaaga aattatacca tatagagagg catttagaag
     4081 tctaggcatg aacccaaata aatttatgag ttcgatagaa gcaatgacaa caagggttgc
     4141 taagaataag aaacttcctc atataaatcc tattgtagat ttaggaaact ctatttcttt
     4201 aaaatattta cttccaatgg gtgctcatga tatggatttt agaaatgatg atgtatatgt
     4261 tagattttct aaaaaagggg ataaatttgt accatttgga gaaactgatg ttgaattaat
     4321 ggaagaagga gaattaattt attcagttgg agacatggta aaaactagaa gatggatatg
     4381 gagacaagga gaagaaggaa aaattactaa tagctcaaaa aatatatttt ttcctataga
     4441 tggttttact gatgctaatt tagataaggt aatgagtgca agagaagaat tagcaaaatt
     4501 gttaaaggaa atatttaatt gtgaaattaa agtaggtttt gtagataaag ataatcctga
     4561 aatggaaata taataagttg ttgaatactt gttaagatat tatatttact taatgatgtt
     4621 aaaaaggtat taaaaaagaa aggtcgtagt aaatttgaaa aaaactataa taaagaatgt
     4681 aaatccaatg attgaaaata agtttatagg actttttgaa atagagtata aaaacaaatt
     4741 agatgaagat aaggtttgga tggtagcatc aagaaaaagt agtgagcaat taaaaaatat
     4801 ttatttgaag aatgaagaag atagtgtaga tgcagttgta atagttgggc ttcataaaag
     4861 tagtaaaaaa ttaattttaa taagacaatt tagagtacct attaatggat atatatacga
     4921 gttaccagca ggtcttgttg atgaaggaga gtctatagat atttccgttg aaagagaact
     4981 tagagaagaa acaggactta ctcttttaga aattaaaaaa aataaaagta ttgataaagt
     5041 ttatttatct cctggaatga gtgatgaatc tgttgccttt gtttattgta tatgtgatgg
     5101 tgatataaca gatgaatttt tagaaccaga tgaagagatt gaagcgcttt taatttcgca
     5161 agaagatgca aaagagattt tacaaagtaa tcataagata gacacaaaag catttttgat
     5221 tttacaaatg tttgtgagtt taggagctaa attatttgaa tagatatata gaaaagaggt
     5281 tatatagaag agtaaaataa taaagtttat tttacttgtg taaattataa tctctttttt
     5341 tatacaataa agtataattt tgtgtatttt taaataagtg atttgactct taaattttca
     5401 taatatgtta taaaccaatt taagatacta caataattaa aattccaaaa ttatttaaca
     5461 tatttgcaat taaaatgaga aaatgtaaag gctgaatgat tgaaaaattt gatgtaaaat
     5521 agtagcttag tttaatacta tagtttgtag ggttaaaaat tagaaattgt aagggagata
     5581 aattctatga aaaaattagt tattatttta attagtatca ttagtatggt tagcttgaca
     5641 gcttgtaaaa aaagcaatga aagtaaatat aataatttaa acaacaaaga atccggacaa
     5701 acaaccattg aaatggactt agataaaaat tatgatactt cagacccatt tgttaatgca
     5761 cgtttgtttt gtgtgtctaa tgatatagat gttttagaca cagagatttc ttttaaaatg
     5821 gatggagata gtggtattgt ggaaataaag gacaataaaa cagatgaaac tttatggagt
     5881 aatacatggc atggaagcgt tgataatgat acattcacaa tttctctttc taatatacaa
     5941 aaagagaaag agtatgctat atgctttact ggaattaaaa taaatcatgc agttgtaaag
     6001 gttacttttg aaagcaattt agttaaggag aaagaaaaac cctcaaaata aattccagct
     6061 tttctataac ttgatattca gtacataaaa gcagttgata tttatgattg actgcttttt
     6121 cttatcaaaa aggataggtt gtgcattttt acttgaaata gtttatgcac atcaaaagtt
     6181 ggtgagcatg atattggaaa tggtaagcat gaaatcttga taatacaagg aaataaattt
     6241 aagttttcaa ttaagtatat ttccataatt tagttaacaa taagctaatt attatttata
     6301 ttttgatata taaataataa ttgtagcaaa ttttaaaaaa tcatatattt tttgaactaa
     6361 ataaaaattt atttttatta ttttaaatta gaggagattc ttgaagatat attattttta
     6421 aaaataagta tagtttaaaa attcaaaaaa aagatggcaa aatatgtccc aagggacatt
     6481 gagtaaaata aatgatttca gcttatttac actaaaaagt acatactaaa tgaggggtaa
     6541 aataaagaaa aatgatatac taattgtctt ttgataataa aaaaacatgg aatttgatta
     6601 tttaatcaag aaaaagtatt gaacaaatga tttatttagt gtacaataat catgtaaaaa
     6661 catagtaatg gagggagaca tttcataatg aaaattaagg taggaatgaa cggatttgga
     6721 agaataggaa gagctgtatt aagaatagct caagaagaat taggagataa tatagaaatt
     6781 gtagccataa atgcaagagc aacaacagaa tctttggcac atttatttac atatgattca
     6841 tgctatggaa cttttagagg tgaagtagag gcaaaggatg aagacactct agtagtaaac
     6901 tctaaagaga taaaaatatt aagatataat gacccagaag aattaccttg gaaagaattg
     6961 ggggttgata tagtaataga atcaacagga ttatttacac aaagagaaaa ggcagaaaaa
     7021 catattaaag caggagcaaa aaaagtaatt ataacagctc caggaaaaaa tgaagatata
     7081 actatagtta tcggagttaa tgagaaagaa tatgataatg aaaagcacaa tataatttca
     7141 aatgcatctt gtactacaaa ttgtctagct ccttttgcta aagtattgga cgaaaaattt
     7201 ggtatagtaa aagggttaat gactacagta cattcatata ctaacgatca aagaatatta
     7261 gataaaagcc ataaagattt gagaagagca agagcagcgg ctgaatctat aatacctacc
     7321 actacaggag cagcaaaagc tgtgtcaaga gtactaccac aattagaagg aaaattaaat
     7381 ggtttttcac ttagagtacc aacaccaaca gtttcacttg ttgatttagt gtgcgaactt
     7441 aaagaaaacg ttacatctga gcaagttaac tctgtgttaa aagatgctgc tgaaggagaa
     7501 ttaaaaggtg ttttaggata ttgtgacaag ccacttgttt ctatagatta taaaggagat
     7561 tcaagatcat ctattataga cgctctatcc acaatggtta tagaagacaa tatggttaag
     7621 gtagtttctt ggtatgataa tgaatgggga tattcttcaa gaactgttga cttagtaaaa
     7681 tatgtagctg aaaaattaaa ataatatata tttcttaaag caaattttaa aaaaattttt
     7741 taaaaaaatt atataaaact aaaaaaaaag attatgaaaa atattgaagg aaaaattttt
     7801 tcataatctt ttttctttca tgcaaaaaga tacaagttac aacttatatt tgcatattag
     7861 gtcgttagag aagtatatat atatttagta aggaatcata ctttttataa aatgaaagat
     7921 aagatgtcga aaacttgcat aaatctgaaa aatttttatt attaaaatac tgatttccat
     7981 tttaaaaatg ataaaaaaat gacaaataaa gttgcaaata gtaatactta taagtataat
     8041 taaaaaagag aaaaggtttt gttaaacttt ataacaaaaa aagaagggat gattcaaaat
     8101 ggagaagtta acagacagga gacaggttaa ggcagtaagc atggaaacct tcattttcct
     8161 aatattacta gtagttggtt ttgggtatgt tggtagtatt atgggagcag gaatgatgtt
     8221 caaagtaata atgagtacag cacatgcttt actattggag acagttttct taattatggc
     8281 tatggcagtt cttgcaggcg cattaagcgc actactttca gagtttggag taatagcgtt
     8341 aattaataaa attttcgctg tatttatgaa gcctttatat ggactacctg gtgctagtat
     8401 agcaggagct ataacaactt atttatcaga taatccagct attatacctt ttgctaaaga
     8461 taaaacattc acacagtatt ttaaacaata ccaagttcca gcattatgta acttaggaac
     8521 agcctttggt atgggactta tcttaacaac atttatgatt tctcaaggta cagaatatgt
     8581 acttccagca ttaattggta atttaggtgc aattataggt agtgtcataa gtgttagaat
     8641 aatgttgaca tttactaaga agttttataa atacaatccg gaagaagata aagcaacagg
     8701 aacattagag aaaaaggatg aatttagaga aatcagagaa ggaaatgtat ttcaaagagc
     8761 tttagatgca attcttgaag gtggtaaaat gggggtagat atgggaatgg ctataattcc
     8821 tggagtccta gtagtatgta cattggtgat gttattaact tttggaccat ctacagatcc
     8881 tgttacaggt caagaagttt atacaggagc tgcatatgaa ggaataaaat tacttccagt
     8941 tattggagat aaacttggat ttatattaga accattattt ggatttacat caccagaggc
     9001 aatagcattc cctataactt cattgggagc tgttggcgca gcaatgtctc tagttccaga
     9061 gtttataaag tcaggagcta taactcctaa tgatatagca gtatttacag ctatgggtat
     9121 gtgttggagt ggatatttaa gtacacatat tggtatgatg gatgcattaa atgctagaca
     9181 gttggcaggt aaagctattc tttctcatac aataggtggt ttatgtgcag gagcagctgc
     9241 tcactttata tttacactcg taggataaat gtaatcagct aagataaaaa ataatataca
     9301 aaaaatggtt gttgatatgt aataagaatt tacatatcaa caaccatttt tttctgacta
     9361 aagataattt ataatacata aacattaagt ggatattaga gttaagttat atttatgtaa
     9421 aaagtaacaa aaatctgtag aaatttatga caaaatttag tacactaact atatgttctt
     9481 atttaaaatt taaggttaga attaggaatt acctagtaga gtaagctttg attaataaaa
     9541 gaatcataaa ataaaaatat tagtcataaa gattataaat aacttactta aaataaagcc
     9601 atagaactta caaaaattaa aaaagcatat aaatatggag gggtacaatg gatgaattat
     9661 ttcatatagg aattgatgta ggttctacaa cggtgaaggt tgtggtactt aataatagta
     9721 ataatatagt tcataaagaa tatagaagac attattctga tgtaaaaaaa tcagttaaag
     9781 aagtactaaa tggtatatat gaaaaattgg gagatataaa tactaccatt ataataactg
     9841 gttcaggtgg aattggaata tcaaaaaaat taggtgtaaa atttgttcag gaagttatat
     9901 ctagtacaaa atcaatagag tattttcatc ctgaaactga tgttgtcata gaacttgggg
     9961 gtgaagatgc aaagataaca tatctaagtg gaggaataga ccaaagaatg aatggaatat
    10021 gtgcaggtgg cactggagca ttcatagacc agatggcatc acttttaaag acagatgcca
    10081 gtggattaaa tgaacttgct aaagggtata atgttatata tcccatagct tcaagatgtg
    10141 gtgtttttgc taaaacagat attcaacctc ttataaatga tggagccaat cagactgata
    10201 tagcaatgag tattttcaat gcagttgtcg tacaaactgt gagtgtcctt tcttgtggaa
    10261 gaaaaataga aggaaatgtt gcgtttttgg gtggtccatt gtacttttta tctgaactta
    10321 gagaagcatt taaaagagta ttagatttaa aagatgaaaa cataatcttc ccagaaaatg
    10381 cacaacttta tattgctatt ggagcaggat tattatcagt agatgaagat aatatacaac
    10441 taaaatctct aatagaaaaa ttggatagta taaagaatat tgaagatgga gaagtaaatt
    10501 tattagaacc tttatttaaa gataaaaatg agtatgaaga attttcaaga agacatgaaa
    10561 aagaaaaaat aaattatgtg gacataaatt caataaaaag caattgttat ttaggaattg
    10621 atgcaggctc aactacaact aaagcagcac ttattgatga ggatggaaga cttgtatatt
    10681 cttattataa tagcaatgaa ggaaatccat taaaaacaac cattaaagtt ataaatgaag
    10741 tatatgatat attaccaaaa aatattaaaa tattgagttc aactgtaact ggatatggag
    10801 aaggtcttat taaaaaagct cttaaaatcg ataatggaga gatagagact atagcacatt
    10861 acaaagctgc taaatttttc aacaaagatg tagattttat acttgatatt ggtggtcaag
    10921 atatgaagtg cctaaaaata aaagatggag taattgataa tataatatta aatgaggctt
    10981 gttcatcagg ttgtggctca tttttagaga catttgcaag ttctttatct atgacaatag
    11041 aagaatttgc gcatgaaggt atttattctc aaaatcctgt agatttaggt tcaagatgta
    11101 ctgtatttat gaattctaga gtaaaacaag ctcaaaaaga aggtgcaagt gttggagata
    11161 tatcagcagg gctatcttat tcagtaataa aaaatgcttt atttaaagta ataaagatta
    11221 gagatttaaa tgagattggt aataatattg ttgtacaagg tggaaccttt tataatgatt
    11281 tggtgcttag aagctttgaa aaactaattg gaaaaaatgt aattagacct aatatttcag
    11341 gaattatggg agcttttggt tcagcactta tagctaaaga aaaatatgaa agtggataca
    11401 aaacatcctt gttatctaag gaagagttga ataatatcaa gctagaagca agtgtaacta
    11461 gatgtaaagg ttgttcaaat cattgtcttc ttacaataaa taaattttct gataatgaaa
    11521 tttttatttc aggtaataga tgtgagaaag gtgaagctat ttatggtgat aaaaaaatag
    11581 gattagaaaa gaaaaaacca ataaatttat ttaagtacaa atacaataga atttttagat
    11641 acaaaccatt ggaaaaagaa gaagcaaaaa atggggaaat agggatacca agagtattaa
    11701 atatgtatga agattatcca ttttggttta cttttttcaa tgctatgggc tttagagttg
    11761 tactttcaga taggtcatca aaacagttat atgaaactgg tataactagt attgcatctg
    11821 aaacagtttg ttatccagga aaattagttc atggacatat agaaaattta attgcaaaag
    11881 gtataaaaaa tatattttat ccaagtgtaa caaatgaaaa taaagaggat tcaaatgcag
    11941 ataattatta taattgtcct gttgtaatat catattctga agtaataaaa aacaatgtag
    12001 agaatataag aaataagaac ataaattata taaatccatt tataagtcta aatgacaagg
    12061 aaaaattgaa gaaaagactc tatgatgaat tatcaagaca tttttctgat ataaaaataa
    12121 ctaaagaaga agttaatcat gcagttgata aagctactga tgaacagaat ttatttaaaa
    12181 tggagataca agcagcaggt gaaagagcac ttaaagaaat aaaagaaaga aatatgaagg
    12241 ggattgtgtt atgtggaaga ccatatcata tagacccaga aataaatcat ggaatgccag
    12301 agcttataaa ttcattagat atggcagtgc ttactgaaga ctctatatgt catttagcca
    12361 atgtacaaag accacttaga gttgtagacc aatgggtata tcattcaaga ttgtataaag
    12421 cagctagttt tgtaagagat aaaaactatt tggaacttgt tcaacttaat tcatttggct
    12481 gtggattaga tgcagtaact acagaccagg ttcaagaaat acttaatgaa aaatcgaaga
    12541 tatatactat tataaagatt gacgaaggca acaatttagg agcagctaag ataaggatga
    12601 ggtccttaaa agcagctatg tttgagagag aaagcaaaaa tatagatgta aaaaatataa
    12661 aggtaaacag gatacagtat gctaaaaata atcagataac gaacaaacat actatattag
    12721 caccacaaat gtctccaata catttccaat tccttgaaaa agctgttaac ttaagtggtt
    12781 ataatataga aattctaaaa gatactgata gtagtgtaat tgaagaaggg ttaagatatg
    12841 taaataatga tgcatgttat ccagctataa tagttgtagg tcagctaata acagcattaa
    12901 aatctggcaa atatgattta aataacactt ctgttactat aactcagact ggtggaggtt
    12961 gtagagctac aaattatatt ggattcttaa gaaaggctat atacgatgct ggatttaaag
    13021 atattcctgt cattgcactt agtgtaaatg gaatagaaga tagtggtata atggataata
    13081 tatcactaaa attaatcaat agactcttta tgtctgttgt ttatggtgat ttgctgatga
    13141 aagtactata tagagtaaga ccatatgaaa aagttactgg aagtgcaaat gctctatatg
    13201 aaaaatgggt tgatatatgc aaatcttctc ttgttaaagc aaaaatttct gtatttacta
    13261 gaaatataaa agatatagta aaagaatttg ataatttaga gatactagat atcaaaaaac
    13321 caaaagtagg tttggttgga gaaatattgg tgaaattcca tccaattgca aataataatt
    13381 tagtagatat attagagcga gaaggtgctg aagcagtcgt gccagacctt acaaatttct
    13441 tcttaagttg tgcctttaat actatataca aacacactca tttagaagga agtagaaaga
    13501 gtagaatgat aggagaagca tttatataca taactggaat atatcaaaga gtatataaaa
    13561 aagcacttga taagagtgag agattttatg ctccagccaa tataaaaaat gttgctaaaa
    13621 gtacagaacc agtagtgtca ttaggtaatc aaactggaga aggttggctt ttaacaggtg
    13681 agatggttga attattaaat gaaggtgtag aaaacattat ttgtatgcaa ccttttggat
    13741 gtttacctaa tcacataatt ggtaagggtt ctataaaaga attaaagagg ttgtataaaa
    13801 atgcaaatat aatacctatt gattatgacc cttctgcaag tgaggtaaat caacttaaca
    13861 ggataaaact tatgctttct aaggctttta aaaatatata agatttatat tttgatatgt
    13921 taaaagttaa tgaatttaaa aatatactct atattaagta tctataaaaa agagttatcc
    13981 tattttttag ggtaactctt tattagttaa aaaattatat gtatactgat attaaagggg
    14041 ggaagtaata tgagtttagt atatgatgtt tataaatcaa aattaggaaa tttgtacata
    14101 ttaagtgaag atggttttat agttagtata tacataggag atgaaaaatt taataattta
    14161 aaaaatgaat gtattaaaaa aggaattgat ataaagagaa gtaaggaaga tttaaaggaa
    14221 gcaataagcc agatagatga ttactttaat ggaaaaagaa aagtctttaa tttaaatatt
    14281 cgtattgaag ggactgaatt tcaaaaatca gtttataggg aaatgttaaa aataccttat
    14341 ggagaaacat tgtgttattc agatatagca agaaatataa acaatccaaa atcagtaaga
    14401 gcaataggac aagcaagtaa aagtaataaa attccaataa taataccttg tcatagagta
    14461 gttggcaaaa aagatattgg tggatatatg gggaatcatt ctgatttgaa agagatacta
    14521 ttaaatttag aaagacagag ttaacttaga aagaaatgtt tttattgtta atatttgata
    14581 taataatagt aaaaagaagt attttttaca aaaacaatga agaatttatt ttaatttata
    14641 aaaatgaggg ggaattttaa tgtgtgataa agttatagca tcaaaatatc atgagaaggg
    14701 atttaattgt gcagaatcag ttataaaagc atataatgag gaatttaata cagatatacc
    14761 agtttgttta ggaagtggac tgggttcagg gtgtggggtt gctagtttat gtggtgcagt
    14821 aaatgcatca aatataataa ttggatatgt aaaaggcaga aaccacgaag atgaaagtac
    14881 taaagctaaa gtatatgcta aagatttaac tacaacagta agaaaagagt atggttcaga
    14941 gttatgtata gacctaaaaa aagatttagt tgcttgtaga gaaataatgg atttcgcata
    15001 tgatagtcta aaggaaactt taaaaaaaga attataagaa aataagctat caagtataaa
    15061 ttatttgata gcttattttt atagtcgata ctaaataaat caaatatatt ttagaattat
    15121 tatttgtaaa taaacagcaa ataattttag gatttttatt taatatagtt tttatttata
    15181 tttatttttg aatatgttat actttgttta aataaatatt tgtaatgagg gagatgagaa
    15241 gattgaagaa tctcaattta cttattaata aattatattc aaaaaatcat aatgaagcat
    15301 ataaaacttt tttattctta gaaaatgaaa gtttaaaatc aaatattaca tattgttttt
    15361 ttgactcatt cctagaaatg attgataacg aaaactcata tattcgaaca aggggattgt
    15421 tattaatctc tgcaaatgct cagtgggata ttgataataa aattgaaata aatatagata
    15481 gtatactaag tcatatcgta gataaaaaac cttctgtatc aagaatgttt attaaatcca
    15541 tacctaatat tacaaagtat aaagaaaatc ttattaatcg cataaaaatg gaattaagta
    15601 atgcagatat aagtatttat aataataata tgaaaccatt agtagaaaag gatataaacg
    15661 atacat
//
LOCUS       DAEPKC010000093        15515 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.093, whole genome shotgun sequence.
ACCESSION   DAEPKC010000093 DAEPKC010000000
VERSION     DAEPKC010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15515)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15515)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15515
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.093"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(321..1571)
                     /locus_tag="KR294_002949"
     CDS             complement(321..1571)
                     /locus_tag="KR294_002949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1015 domain-containing protein"
                     /protein_id="HBH0241011.1"
                     /translation="MATIKPFKAIRPNKYIVDKVAALPYDVMNSKEARRIAEGNPYSF
                     LHIDKSEIDLDENIDLYDEKVYLKARENLDEFRKQEILVKDDKECIYIYKQIMDGRAQ
                     VGIVACISVDESLNGTIKKHEYTRPEKEIDRTKHIKYCDANTGTILVTYKHQRVIDDI
                     INDFMDNNEPLYDFITDDKIEHTVWKIDNDDIIDNLVDKFEKLDYLYIADGHHRTASA
                     ENVAKEMRAKNPNYTGKEEFNYFIAMIAPDENLMVLDYNRVIKDLNGLSEEEFINKIK
                     ENFELEEIEGKEKYKPDKKGTFGMYLGDKWYKMKANKNLLEIEDPVDSLDISILQDYV
                     IDAILGIDNPRVDKRIDFIGGIRGLEELEKRVNEDMKVAFAMYPTSIEDLIRVADANK
                     IMPAKSTWFEPKVRCGLFLHEINE"
     gene            complement(1604..2545)
                     /locus_tag="KR294_002950"
     CDS             complement(1604..2545)
                     /locus_tag="KR294_002950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-3-phosphoglycerate dehydrogenase"
                     /protein_id="HBH0241012.1"
                     /translation="MYNILVTDGIEKEAARKLRELDFNVIEQFYEKDVLGDKLKDVDV
                     LVVRSATKVTKDVIDKALEGKKLKLIVRGGVGLDNIDVKYAQANGIKVMNTPNASSIS
                     VAELTIGQLFVLARFINTANVTMRDGKWEKKKYKGTEINGKTLGLIGFGRIAKEVAKR
                     AELLGMNVIYTDIMGEAQGFNNYKFCDMEEVLENADFLSLHIPFDKNKGAVITEKEIN
                     KMKKGAYLINCARGGLVDEKDLLKALDEGKLSAAAIDVYEQEPTLNLDLVNHPRVSPT
                     PHIGASTVEAQERIGDEIVNVIQDFFLDFNNLIGVAL"
     gene            complement(2785..3861)
                     /locus_tag="KR294_002951"
     CDS             complement(2785..3861)
                     /locus_tag="KR294_002951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--glyoxylate aminotransferase family
                     protein"
                     /protein_id="HBH0241013.1"
                     /translation="MSKKLFIPGPIDVKEEVLQKMATPMIGHRGKDASMLQKSISEKM
                     QKLFYTNNTILLSTSSGTGLMEGSIRSCTSKKAAVFSCGSFGDRWYKMAVANNVPADI
                     FKVELGEATTPEMVDKVLSTGEYDLITVTHNETSTGIRNPIEEIGEVVKKYEDVIYCV
                     DTVSSAGGIKVEVDKIGIDICITSVQKALGLPPGMSICTFSQKAIDRAKQVPFRGVYL
                     DLLAMYEYLIKKNYQYPSTPSLSHMFALDFQLDNILDEGLDNRFNRHEDMANLVRNWA
                     KKHFQIFTNENHLSNTLTVIENTQGISVSNLNSKLQERGFQIANGYGDLKEKTFRISH
                     MGDYTVEDVQELLDNIDDILGFNK"
     gene            complement(4234..4749)
                     /locus_tag="KR294_002952"
     CDS             complement(4234..4749)
                     /locus_tag="KR294_002952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HBH0241014.1"
                     /translation="MDFLAKYKVLKKQNSSKSCLVCGTQNELGLKADFYELENGELVS
                     ICNTKDWHQSYPGRVHGGMSAAILDETIGRAVSINDDQIWGVTVSLELKYKKPVPTDA
                     TIKVVGRITKENRKLFEGTGEIILPNGDIAVTATGKYMKMPIGQIAEGDFSNEEWFFE
                     ESKEKVEYIEL"
     gene            complement(5112..6182)
                     /gene="leuB"
                     /locus_tag="KR294_002953"
     CDS             complement(5112..6182)
                     /gene="leuB"
                     /locus_tag="KR294_002953"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HBH0241015.1"
                     /translation="MNCNIAVIKGDGVGPEIIDEGIKVLNKICCKFNHRFDCEYVLAG
                     GCAIDETGEPLPNKTVETCRKNEAVLLGSVGGPKWDKCKGDKRPESGLLKLRESLGLF
                     ANLRPATMYESIKEASPLRTDIVEKGIDFVVVRELTGGIYFGERGRKIIDGIENAYDV
                     EIYNENEIRRIGKRAFEIARNRNKKLISVDKANVLESSRLWRSIMEDLAKEFEDVELS
                     HMYVDNAAMQVVKDPSQFDVIVTNNIFGDIISDEASMITGSIGMLPSASLREDSFGMY
                     EPIHGSAPDIAGKDIVNPIATILSVSMMLRHSFNLEEEAKCIEDAVQSVLNKGYRTID
                     IYNGVGNVVGTREMGELIVNEI"
     gene            complement(6189..6680)
                     /gene="leuD"
                     /locus_tag="KR294_002954"
     CDS             complement(6189..6680)
                     /gene="leuD"
                     /locus_tag="KR294_002954"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HBH0241016.1"
                     /translation="MIANGSVFKFGDNIDTDVIIPARYLNIADYKELATHCMEDIDDK
                     FISKVKKGDIIVATKNFGCGSSREHAPIVIKESGVSCVIASTFARIFFRNSINIGLPI
                     LECEEAANNIDEGDNIEVDFSTGVIKNITKGKEYKAEPFPEFMQNIILNEGLINSIKA
                     NRG"
     gene            complement(6695..7972)
                     /gene="leuC"
                     /locus_tag="KR294_002955"
     CDS             complement(6695..7972)
                     /gene="leuC"
                     /locus_tag="KR294_002955"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase large subunit"
                     /protein_id="HBH0241017.1"
                     /translation="MGMTMTQKILAKHAKLNEVKKGQLIEADLDVVLGNDITSPVAIR
                     EFEKLGIEDVYDKTKVVMVLDHFTPNKDIKSAEQCKFTRSFAKSKGVVNFFDVGDMGI
                     EHVLLPEKGIVTAGDVIIGADSHTCTYGALGAFSTGVGSTDMGAGMATGKCWFKVPGA
                     IKFVLKNKPNKWISGKDIILHIIGEIGVDGALYKSMEFCGDGVEYLSMDDRFTICNMA
                     IEAGAKNGIFPVDDKTMEYINSHKCSTMTKDVNIYEADEDAVYDEVYEIDLAELKETV
                     AFPHLPENTRTVDEIDKDIKIDQVVIGSCTNGRISDLEVVAEIMKGKKVADGVRVMIF
                     PGTQKVYLEAIEKGYITTFIEAGAAVSTPTCGPCLGGHMGILAAGEKSISTTNRNFVG
                     RMGHVDSEVYLASPAVAAASAITGKISKPSEII"
     gene            complement(7929..9671)
                     /gene="leuA"
                     /locus_tag="KR294_002956"
     CDS             complement(7929..9671)
                     /gene="leuA"
                     /locus_tag="KR294_002956"
                     /EC_number="2.3.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HBH0241018.1"
                     /translation="MKCGKYKKYDKMQIVNRKWPDNEIFKAPIWCSVDLRDGNQSLPT
                     PMSVNEKVRMFKMLIDTGFKEIEVGFPSASNTEYTFLRKLIDENMIPDDVTIQVLTQS
                     RAHLIEKTFESIRGCKKAIIHLYNSTSVLQRDVVFNMSKQEIIDIAVEGAKLFNEEVK
                     KYPETEFTFEYSPESFTGTEMDYALEICEAVIDVWKPTPQKKVIINLPSTVEMATPNV
                     YADQIEWFCKNISCRDSIILSLHTHNDRGTCTAASELGLLAGADRLEGTLFGNGERTG
                     NMDIVNVGLNLYTQGIDPELDFSNIDKIIGIYEDCTKLMVHDRHPYAGNLVHCAFSGS
                     HQDAIRKGMIAMKNRDNDYWEVPYLPIDPHDIGREYKEIIRINSQSGKGGAVYIMETD
                     YGFMIPKNMHSDFGNVVKMESDRIGEELSSEAIFNLFKKEYIEVESPYKVKKYKIKSM
                     DELNYENDDSNDTNMIEMTARISYMGNEQRIVGIGNGPVDSFNNALKQCGMKDYKFRY
                     YWEHALEEGSHSRGVAYVGIEHNNEVYFGVSISENINTAAINALMNAINKSYIEEEIK
                     NGDDYDAENISQTC"
     misc_binding    complement(9795..10041)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(10189..10635)
                     /locus_tag="KR294_002957"
     CDS             complement(10189..10635)
                     /locus_tag="KR294_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241019.1"
                     /translation="MSKNKFIYMNYYDNGYFKKGMTIYMVLALIILATIFIYSTTILY
                     ILCIITAVFLFKQGRDFSNKYEGKVYITLDNHSILINNQCIFSIKSKQSQKFNYKIIE
                     KIEVVKNILNIYTNESNYKIRLRALSLEDEKKLLNIIDEKMKKFKA"
     gene            complement(10656..11375)
                     /locus_tag="KR294_002958"
     CDS             complement(10656..11375)
                     /locus_tag="KR294_002958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase"
                     /protein_id="HBH0241020.1"
                     /translation="MKKSIMDVHCHTLISGHAHSTFKENVEEASKKNIKYLGISDHGP
                     NMPGGPHPFYFYNLHLLPREVQGVKILRGIEGNIMDYNGNLDVQEDMLQHLDYIIASL
                     HRPCIASGTKEENTNAILKVMDKPKVKIIGHPDDSRYPLDYEPIVKKAKDKNILLEIN
                     NSSLSSNSHRTGTWENVSHMLTLCKTYGARVILGTDSHICYSIGEFENAEKVLEAVDF
                     PDELVINYHEDEIIEFFDINF"
     gene            complement(11493..12767)
                     /locus_tag="KR294_002959"
     CDS             complement(11493..12767)
                     /locus_tag="KR294_002959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HBH0241021.1"
                     /translation="MFIMENDLTMQELLDQQEQVFSKVKVGELTTGKITAVRNDEVQL
                     GLDYGFDGIIPISELNIEKNQYIEDIYHIGDEITAVITKVSQKDGTITLSKLQLDKRN
                     DFAELQKAYDEHRIITVNVEKNIDKGVFANYNTYTFFIPISQLDTKFITDTSKFVGLN
                     LEVYIKELDVRKNRLVASHRDVLQERINKEREERRAQIKAEKEAERARIKQEREEEKA
                     RIKAAKEDLFNSLEVGQKRDGKVTKIMPYGAFVDIGGIEGLAHINNLAWTRVESVEDV
                     VSEGQEVEVYVLDVNKETKKIALALKDINNDPWDLIAKEVQIDDVVNAKVLRIIEKGA
                     FVQIKEGVDAYLPISELSDTRVAKVTNVVNIGDEVKVKILDFKPKTKRMLVSIKEATR
                     EPEEDITEYLEVEESLGSIGELFKDKFKDLEV"
     gene            complement(12967..14334)
                     /locus_tag="KR294_002960"
     CDS             complement(12967..14334)
                     /locus_tag="KR294_002960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBH0241022.1"
                     /translation="MENSNTNLGSESVGKLLFKLATPAIIAQIVNVLYNIVDRIFIGR
                     MENGEVAMAGVGVAFPIIIIITACSYLIGMGGGPLAAIKMGEQNNDEAEKIMSNSFSV
                     LVILAILLTIGFKIGKEPLLWMFGASESTIGYSMDYLNIYLIGTVFVQISMGMNTFIN
                     TQGFATTGMMTVAIGALINIILDPIFIFGFNMGVKGAALATIIAQGVSAIWVLMFLFG
                     KKSILKIKKKYMIPKASIILPVLGLGISPFIMQSTESLVLIALNSKLQMYGGDLAVGS
                     MAIMSSIMQILMLPNMGVTQGAQPIISYNYGSGQLDRVKKTFKLCLLSCFTYSTILWL
                     LLMIFPAFFVSIFNKNPQLLSMTSWSIKIYFAGAFMFGIQIACQQTFLALGKATISLV
                     LALLRKIVLLIPLIFILPTFFNEKLFAVILAEPVADITAATITAISFFIFYKCFLSKP
                     KAIKE"
     gene            complement(14584..15048)
                     /locus_tag="KR294_002961"
     CDS             complement(14584..15048)
                     /locus_tag="KR294_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small multi-drug export protein"
                     /protein_id="HBH0241023.1"
                     /translation="MSLRIGGNSLGYLHILILSMVPVTELRGAIPIGIAMGLNPIWVY
                     VFSVIGSTLVSIPLILTFRHVLQFLRGKKLFKGIADVIDRKINSRMKKLKSVSIIGII
                     LFVGIPLPTTGTWTASAIASILKMRIKDAFMGVFLGNLLSGVIVSALSLHII"
     gene            complement(15053..>15515)
                     /locus_tag="KR294_002962"
     CDS             complement(15053..>15515)
                     /locus_tag="KR294_002962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HBH0241024.1"
                     /translation="KKAKEAIFYPIVDFSEEDLKKFFDDCIMKKINESMKKVIYKNKE
                     EDNVIIMITASPYAYMKYFKYYGLADEVIGTEFFYENSRYKNKFIGENCKGIEKVKRI
                     KAVLGKLGIEIDYENSYAYSDSKSDLPMLSLTKNAFLVSKKDGEVIEQINS"
BASE COUNT         4853 a         2935 c         1592 g         6135 t
ORIGIN      
        1 aattatattt ataaaaataa aatataaatt tcaaaatcac tttttttatt aactttttta
       61 taattataat aaaaatatat aacagtacta ttataaatac acatttaaaa ccttataaat
      121 atacaaatac aattatatga attttcatcc tcaattatag catagaatat gactatctat
      181 atcctaaaat tatccatttc taaaaaaaag gtaactatta ttaagaatat caacttatag
      241 aatttatatt ccacatacga ttttcaatca aaaaaacaag ggctaaaaag tgaattgtgc
      301 actttttagc cctttattaa ttattcattt atttcatgta agaatagacc acatcttact
      361 ttaggttcaa accatgttga cttagctggc attatcttat ttgcatctgc tactcttatt
      421 aaatcttcaa tactagtagg atacattgca aatgctactt tcatatcttc attaactctt
      481 ttttctaatt cttcaagacc tctaattcca ccgataaaat caattctttt atctactcta
      541 ggattatcaa ttcctaaaat agcatcaata acatagtctt gtaatataga aatgtctaat
      601 gagtcaacag ggtcttctat ttctaataaa tttttatttg ctttcatttt ataccactta
      661 tcacctaggt acattccgaa agttcctttt ttgtcaggtt tatatttttc ttttccttct
      721 atttcttcta gttcaaaatt ttcttttatt ttatttataa attcttcctc gcttaaacca
      781 tttaagtctt tgataaccct attataatcc aaaaccatta aattctcatc tggtgcaatc
      841 attgctatga agtaattaaa ttcttctttt ccagtataat ttggattttt agctctcatt
      901 tctttggcta cattttctgc tgaagctgtc ctatgatgac catctgcaat gtatagataa
      961 tctaattttt caaatttatc tactaggtta tctattatat catcattatc aatcttccat
     1021 actgtatgct ctatcttgtc atctgttatg aaatcatata aaggttcatt attatccata
     1081 aaatcattga ttatatcatc tatcaccctt tgatgtttgt aagttacaag tatagttccc
     1141 gtattagcat cacagtattt tatgtgttta gttctatcaa tttccttttc tggtcgagtg
     1201 tactcatgtt tttttattgt tccattcaag ctttcatcaa ctgatataca tgctactata
     1261 ccaacttgag ctctaccatc catgatttgt ttatatatat atatacactc tttgtcatct
     1321 tttactagaa tttcttgttt tcgaaactca tctaaatttt ctcgcgcttt taaataaact
     1381 ttttcatcat ataaatctat attttcatct aaatcaattt ctgatttatc tatatgcaaa
     1441 aatgaatatg gattcccttc tgcaattctt ctagcttctt tactattcat aacatcgtaa
     1501 ggaagtgctg ctactttatc tactatatat ttatttggtc taatcgcctt aaatggttta
     1561 atcgttgcca ttactaattt cctccctaat tatacaaaat attttataat gctaccccta
     1621 ttagattgtt gaagtcaaga aagaaatctt gaatcacatt tactatttcg tctcctattc
     1681 tttcttgagc ttctactgta gatgccccaa tatgaggtgt aggagaaact cttggatgat
     1741 ttactaagtc taaatttaat gtaggttctt gttcataaac atctatagca gctgctgata
     1801 atttaccttc atctaatgct tttagtaaat ctttttcatc aactaaaccg cctcttgcac
     1861 agtttattaa ataagcccct ttcttcatct tatttatttc tttttcagtt attactgccc
     1921 ccttattctt atcaaatggt atgtgtaaag ataagaaatc tgcattttct aaaacttctt
     1981 ccatatcaca gaatttataa ttgttaaagc cttgcgcctc acccattatg tcagtatata
     2041 taacattcat acctaataat tctgctctct ttgcaacttc ttttgcaatt cttccaaaac
     2101 ctataagtcc aagtgtcttt ccattaattt ctgtaccttt atactttttc ttctcccatt
     2161 ttccatctct catagttaca tttgcagtat ttatgaatct tgcaagaaca aataattgac
     2221 ctattgtaag ctctgcaaca gatatactgc ttgcatttgg agtattcata acttttatgc
     2281 cattagcttg agcatattta acatctatat tatccagacc tactccacct cttactatca
     2341 acttcaactt tttaccctct aatgctttat ctattacatc tttagtaact ttagtagctg
     2401 aacgtactac aagtacatca acatctttaa gtttatctcc taaaacatct ttttcataaa
     2461 actgctctat cacattaaaa tctaactctc tcaattttct cgctgcttct ttctctattc
     2521 catcagtaac taatatatta tacataacaa actcctccaa tttttattca cttaattttt
     2581 ccaattttta ttttttaaag tattttcatc aataaaaaac tttacttaat ttaactttct
     2641 gtttatataa ttttcaaaat atttttttat taaagtcata tcaaattttc ctattgtttg
     2701 ttaaaaattt aatatgtaat ttttataaaa tattatttat tatatattct aaatttatct
     2761 taaaacatac atatttttac aatattattt attaaaacct aatatatcat caatattatc
     2821 taataattct tgtacatctt cgacagtata gtcacccata tgtgaaattc taaaagtttt
     2881 ttcttttaaa tctccatagc catttgctat ttggaatcct cgttcttgta attttgaatt
     2941 taaatttgat acactaatac cttgagtatt ttctataaca gtaagtgtat tggataagtg
     3001 attttcattg gtaaaaattt ggaagtgttt tttagcccag tttctaacta agtttgccat
     3061 gtcttcatgt ctgttgaatc tgttatctag gccttcatct aatatattat ctaattggaa
     3121 atctaaagcg aacatgtgag aaagagatgg tgttgaaggg tattggtagt ttttcttgat
     3181 taagtattca tacattgcta acaaatcaag atatactcct ctaaaaggta cttgcttagc
     3241 tctatcgatt gctttttgag aaaatgtgca aatagacatt cctggtggta atcccagtgc
     3301 tttttgtact gatgttatac aaatatctat tccaatctta tcaacctcga cttttattcc
     3361 accggctgaa cttacagtat ctacacagta gattacatct tcatactttt taacaacttc
     3421 tccaatttct tctattggat ttcttattcc agttgaagtt tcattgtgag ttacagttat
     3481 taaatcgtat tctccggtag aaagcacctt atcaaccatt tctggcgttg ttgcctctcc
     3541 taattcaact ttaaatatat ccgctgggac attattagcc actgccattt tgtaccatct
     3601 atcaccaaag gatccacagg aaaatactgc tgcctttttg gatgtacagg aacgaatgga
     3661 gccttccatt aaaccagttc cggatgacgt ggataaaagt atcgtgttgt ttgtatagaa
     3721 tagtttttgc atcttttcac ttatactctt ttggagcata gatgcatctt ttcctctatg
     3781 tcctatcatt ggtgtagcca tcttttgcaa gacttcttct ttaacatcaa taggaccagg
     3841 aataaataat ttcttactca ttataattcc ccccttttta gtttgtaata tggatagcgt
     3901 ttttactgtc cttattttta ataactataa tatcaagctg aattaactat gtcaacataa
     3961 aatttatttt ttatatataa tttattttat atattttatg aaaacattca ttttctacct
     4021 tttcataagt ctgaattttc tgaattattc tctcaaaaaa aatatacttt ttatctatat
     4081 aaattaattt ttttagtatg taaatttgac gctattacga taaatctttt tagtataact
     4141 aatttatttt tatcttgtat ttttattgta tttttgaatt ttattttttc taaatataaa
     4201 atttatgttt taaaatgtaa aatttttatt taatcaaagt tcaatatatt ccactttttc
     4261 tttcgattct tcaaaaaacc attcttcatt agaaaaatca ccttctgcaa tttgtccaat
     4321 aggcattttc atatactttc cagttgctgt cactgctata tctccatttg gtagaattat
     4381 ttctcctgta ccttcaaata attttctgtt ttctttagtt attcttccaa caacttttat
     4441 agtagcatct gttggtactg gtttcttata tttcaactct aaagatactg ttactcccca
     4501 tatttggtca tcatttatac ttacagctct tccaatagtc tcatccaata ttgcagcaga
     4561 catacctcca tgaactctcc caggataact ttgatgccaa tcctttgtat tacaaattga
     4621 tacaagctct ccattttcaa gttcataaaa atctgcttta agtcctagct cattttgtgt
     4681 tccacaaact aaacaagatt tactactatt ttgcttcttc aaaactttat actttgccaa
     4741 aaaatccatc tcctaaccga cattagtagt cgcttaatat taaataattc taaaatatat
     4801 tatataatat taataaaatc cctgcaaact tctaataata aaaataggct acttcaatat
     4861 gataagttta atttaaagta ttattttcca aaaaataact ttatcaaaat agaaactcaa
     4921 agtagatata aacctctttt tcgttattaa aatagtaaaa atatatttga cttaatataa
     4981 aaaagagtgt ctcattaact aataaagttt attttgagac acccctcata aaacaaatta
     5041 tactacaata gatttttact aattctacaa gttatatatt taaattatat tattcaaatt
     5101 aaactataat tctaaatttc atttactatt aattcgccca tttcccttgt tcctacaaca
     5161 tttcccacac cattatagat atcaatagtt ctataacctt tattgagtac actttgtaca
     5221 gcatcttcaa tacacttagc ttcttcttct aagttaaaac tatgtcttaa catcatgctt
     5281 acagatagaa tagtcgcaat tggatttaca atatcttttc cagctatatc aggtgcactt
     5341 ccatgtattg gttcatacat accaaaacta tcttctctaa gtgatgctga tggtaacata
     5401 cctatagaac ccgtaatcat agatgcttca tcagatatta tatctccaaa tatattatta
     5461 gtcactatta catcaaattg gctagggtct tttacaactt gcatagcagc attatcaaca
     5521 tacatatgtg acagttctac atcttcaaac tctttagcta agtcttccat tatacttctc
     5581 caaagtcttg aactctcaag cacatttgcc ttatctacac ttataagttt tttatttcta
     5641 tttctggcta tttcaaaagc tctcttacca attcttctta tttcattttc gttatatatt
     5701 tctacatcat aagcattttc gataccatca atgatttttc ttccacgttc tccaaaataa
     5761 atgccccctg ttaattccct tacaacaaca aaatcaatgc ctttctcaac tatatccgtt
     5821 ctaagtggtg aagcttcttt tatactttca tacattgtag ctggtcttaa atttgcaaat
     5881 aaacccaatg actctcttaa ttttaaaaga ccagactctg gtcttttatc tcccttacat
     5941 ttatcccact ttggtcctcc aacagaacca agcaatacag cttcgttttt tcgacaagtt
     6001 tcaacagttt tattaggtag aggttctcca gtttcatcaa tcgcgcatcc tccagctaat
     6061 acatattcac aatcgaatct atgattaaat ttacaacaaa ttttatttag aacctttata
     6121 ccttcatcta taatttccgg tccaacacca tcacctttta tgactgctat attacaattc
     6181 atactccact accccctatt tgcttttatt gagttaatta agccttcatt taatataata
     6241 ttttgcataa actcaggaaa tggttctgct ttatattctt ttccttttgt tatatttttt
     6301 atcacacctg tagaaaaatc tacttctata ttatcccctt catctatgtt attggcagct
     6361 tcttcacatt caagtatagg aagccctata tttatagagt ttctaaaaaa tattctagca
     6421 aaagtagaag caatcacaca ggatactcca ctttctttta ttacaattgg tgcatgttct
     6481 cttgatgaac cacaaccaaa gtttttagtt gcaactataa tatctccttt ttttacctta
     6541 gaaataaatt tatcatcaat atcctccata caatgcgttg ctagttcttt ataatcagct
     6601 atatttaaat atctagctgg tattattaca tctgtatcta tattgtcacc gaatttaaaa
     6661 acacttccat tggcaatcat aaattttacc tcccttaaat tatttctgat ggttttgata
     6721 tttttccagt tatagctgat gctgctgcta cagctgggct tgcaagatac acctctgaat
     6781 caacatgccc cattcttcct acgaaattcc tatttgttgt tgaaatggat ttttctcctg
     6841 ctgcaagtat acccatatgt ccccctagac atggaccaca agttggtgta gaaactgctg
     6901 ctcctgcctc tataaaagtg gtaatatacc ctttttctat agcttcaaga tatacttttt
     6961 gagttccagg aaatatcata actctaactc catctgctac ttttttgcct ttcattatct
     7021 cagctactac ttcaaggtct gatattcttc catttgtaca agagcctatt acaacttggt
     7081 ctatctttat atccttatct atctcatcta ctgttctagt attttcagga agatgaggaa
     7141 aggctactgt ttcttttagt tcagctaaat ctatttcgta tacttcatca tagactgcat
     7201 cttcatctgc ttcatatata tttacatctt ttgtcatagt tgaacactta tgtgaattta
     7261 tatattccat agtcttatcg tctactggaa aaattccatt ttttgctcct gcttctattg
     7321 ccatattaca aatagtaaat ctatcatcca tagataagta ttctactcca tctccacaaa
     7381 attccattga cttgtaaagt gctccatcaa cacctatctc ccctattata tgaagtatta
     7441 tatctttacc acttatccat ttatttggtt tattcttcaa aacaaatttt attgctccag
     7501 gaaccttaaa ccaacatttt cctgtagcca tacctgctcc catatcagtt gaacctacac
     7561 cagtagaaaa tgctcctaat gctccatatg tgcaagtatg agagtcagca cctataatta
     7621 catctccagc agttactata cctttttcag gaagaagaac atgctctatt cccatatctc
     7681 ctacatcaaa aaaatttaca actccttttg attttgcgaa acttcttgta aatttacatt
     7741 gttctgcact ctttatatct ttattaggtg taaagtggtc taaaaccatc actactttag
     7801 tcttatcata aacatcttca attcctaatt tttcaaattc tctaatggct actggtgatg
     7861 ttatatcatt acctaaaact acatctaaat ctgcttcgat taattgccct ttcttaactt
     7921 catttaattt agcatgtttg gctaatattt tctgcgtcat agtcatcccc attttttatt
     7981 tcctcctcaa tataactttt atttattgca ttcataagtg cattaatagc tgctgtattt
     8041 atgttttccg atatacttac accaaaatag acttcattat tgtgctctat tcctacataa
     8101 gctacccctc ttgaatgtga cccttcctct aatgcatgtt cccagtaata tctaaattta
     8161 taatctttca tgccacattg ctttagtgca ttattaaatg aatctacagg tccatttcct
     8221 ataccaacaa tcctttgttc atttcccata taacttattc ttgcagtcat ctcaatcata
     8281 ttagtatcat tagaatcatc attttcatag tttaattcat ccattgattt tattttatac
     8341 ttcttaactt tataagggct ctcaacttca atatattctt tcttaaacaa attaaatatt
     8401 gcttcactac taagttcttc cccaattcta tcagattcca ttttgactac atttccaaaa
     8461 tcagaatgca tatttttagg tatcataaat ccataatctg tttccattat ataaacagct
     8521 cctccttttc cagattggct atttatcctt ataatttctt tgtattctct tccaatatca
     8581 tgagggtcta ttggtaaata tggaacttcc cagtaatcat tatctctgtt tttcattgct
     8641 atcatgcctt ttctaatagc atcttgatgt gaacctgaaa aagcacaatg tacaagatta
     8701 cctgcatatg gatgtctatc atgtaccata agttttgtac agtcttcata tatacctatt
     8761 atcttatcta tattgctaaa atctagctct gggtctattc cttgtgtata aagattaagt
     8821 cccacattta ctatatccat attcccagtt ctttcaccat ttccaaatag tgttccttca
     8881 agtctatcgg caccagccaa taatccaagt tcacttgcag ccgtacaagt tcctctatca
     8941 ttgtgagtat gcaaacttag tataatagaa tccctacaac ttatattttt acaaaaccat
     9001 tctatttggt ctgcatatac gtttggtgtt gccatttcaa ctgttgatgg aagatttatt
     9061 attacttttt tttgaggagt tggtttccaa acatctatca ctgcctcaca tatttcaagt
     9121 gcataatcca tctctgttcc tgtaaaactc tctggtgaat attcaaaagt aaattctgtt
     9181 tctggatatt tttttacttc ttcattaaat aattttgctc cttcaactgc tatatctatt
     9241 atttcttgtt tactcatatt aaaaaccaca tctctttgaa gaacagatgt agagttatat
     9301 aaatgtataa ttgctttttt acatcccctt attgattcaa atgttttttc tataagatga
     9361 gccctagatt gtgtaagtac ttgtatagtt acatcatctg gaatcatatt ctcatctatt
     9421 aattttctta aaaatgtata ctctgtattt gatgctgatg gaaatcctac ctctatttct
     9481 ttaaatcctg tatcaataag cattttgaac attctgactt tttcatttac actcataggt
     9541 gttggcagtg actgatttcc gtctcttaaa tcgacactac accaaattgg agccttaaat
     9601 atttcattat ctggccattt acgatttact atttgcattt tatcatattt tttatacttt
     9661 ccacacttca tgttatttcc ccctttttct gttttttgta ttcagtatac ctcatatcga
     9721 cgcaatcctg cacaattcat aaggataaat gtcaatttta tcattagaat aaaaaaaacc
     9781 tcatctctaa taaaattaga gacgaggttt tgctcgcggt accactctat ttagctttct
     9841 aaaaagctcc cttagtaata gccaatacaa taattataat gactatattt cctataacgt
     9901 ggaattactc cgattattct aagatttaaa tcttagaaaa cagctcctag acaagttcag
     9961 aactatcaac tactaaatca caccatcctt tagctctctg aaagtttcat tgttcttact
    10021 acttctattc atcacttttt taatcattta aattttctaa atattttgat ttaatagtta
    10081 ttatatacac attaaaatgt attgtcaaca caaaaaataa ttatctcaat tttttatttt
    10141 tgataagcaa ttctataaaa catgctaact attgaaaaca gtatgatatt atgccttaaa
    10201 ctttttcatc ttttcatcta tgatattcaa taattttttt tcatcttcca aactcaatgc
    10261 ccttaatcta attttataat tagattcgtt agtgtatata tttaatatat tttttactac
    10321 ttctattttt tctattatct tataattaaa cttttgactt tgtttagatt ttatactgaa
    10381 tatacattga ttatttatta atattgaatg attatcgaga gtaatatata cttttccctc
    10441 atatttattt gaaaaatcac gaccttgttt aaatagaaaa actgctgtta ttatacataa
    10501 aatatataat attgtcgttg aatatataaa aattgtagct aaaattataa gtgctaaaac
    10561 catatatata gtcattcctt ttttaaaata accattgtca taataattca tatagataaa
    10621 cttattttta ctcaaatttt ttcactccca agattctaaa aatttatatc aaaaaattct
    10681 ataatttcat cttcatgata atttatgact aattcatctg gaaaatctac tgcttctaaa
    10741 actttttctg cattttcaaa ttctcctata gaataacata tatgagagtc agtaccaaga
    10801 attactcttg caccatatgt tttacacaat gtcaacatat gacttacatt ttcccaagta
    10861 cccgttctat gagagtttga acttaatgat gaattattta tttctaaaag gatattttta
    10921 tctttagctt tttttactat aggttcataa tctaaaggat acctactgtc atctggatgt
    10981 ccaattattt ttaccttagg tttatccata acttttaaaa tagcatttgt attttcttct
    11041 tttgtaccag aagctataca aggtctatgc aaacttgcga ttatataatc caaatgttgc
    11101 aacatatctt cttgaacatc taaattacca ttataatcca ttatatttcc ttctattcct
    11161 ctaagaatct ttacgccttg cacttcacgt ggaagcaaat gcaaattata aaaatagaat
    11221 ggatgtggtc ctcctggcat attaggtcca tggtctgata ttcctaagta ttttatattc
    11281 ttcttactcg cctcttcgac attttccttg aaagtactat gtgcatgtcc acttattaga
    11341 gtgtgacaat gtacatccat aatagacttt ttcattaaat ttcctcctaa tattttacat
    11401 aaattcgtga aaatagctaa agggctattt caaaactaaa gctgtcataa tagacagtgt
    11461 aacgttttaa aacagcccca ttttcaatta ttttacactt ctaaatcttt aaatttatct
    11521 ttaaataatt ctccaatact tcctaaagat tcctctactt ctaggtattc tgttatatcc
    11581 tcttctggct ctctagttgc ttcttttatt gaaaccaaca ttctcttagt ctttggttta
    11641 aaatcaagaa tcttaacttt aacctcatct ccaatattaa caacattagt aactttagcc
    11701 actctagtat cactcaattc agatattggt aaatacgcat ctacaccttc tttaatttga
    11761 acaaaagccc ctttttctat tattctaaga actttagcat tgacaacatc atcaatttgt
    11821 acttcttttg ctattaaatc ccaagggtca ttatttatgt cttttaatgc caaggcaatt
    11881 tttttagtct ctttatttac atccaacaca taaacttcta cttcttgtcc ctctgaaaca
    11941 acatcttcaa cactttcaac tcttgtccaa gctaaattat ttatatgtgc taatccttca
    12001 atcccaccaa tatccacaaa tgcaccataa ggcattatct ttgtcacctt accatctctt
    12061 ttttgtccaa cttcaagaga attaaataag tcttctttag ctgctttgat acgagctttt
    12121 tcttcttctc tttcttgctt aattcttgct ctttcagctt ctttttctgc cttaatttga
    12181 gctcttcttt cttctctctc tttatttata cgctcttgta atacatctct atgagatgct
    12241 acaagtctat tttttctaac atccaattct tttatataaa cttctaagtt aagaccaaca
    12301 aatttagatg tatctgtaat aaattttgta tcaagttgag aaattggtat aaaaaatgta
    12361 tatgtattgt aattagcaaa tacaccttta tctatattct tttcaacatt tacagttatt
    12421 attctatgtt catcataagc cttttgtaac tcggcaaaat catttctttt gtcaagttgt
    12481 aatttagata aagttattgt accatctttt tgagatactt ttgttattac agcagttatt
    12541 tcatcaccta tgtggtatat atcttctata tattgatttt tttctatgtt caattcactt
    12601 ataggtatta ttccatcaaa cccatagtct aatcctaatt gtacttcatc atttctcact
    12661 gcagttattt ttccagttgt caattctcca actttcactt tgctgaatac ttgttcttgc
    12721 tggtcaagta attcttgcat tgttaaatca ttttccatta taaacatcct ttcctcttat
    12781 tgattatcat atctgtaaat attataccat taatattgca aatacttaca tttttcttac
    12841 tataattttt aaaataaatt caacttcata tatttataca ttatagaaaa tatcttatta
    12901 aattaaaata caaattctaa tttttatcta ataaaatatt ttcataaaaa atttatattg
    12961 tatatcttat tcttttattg ctttaggttt tgatagaaaa catttataaa atataaagaa
    13021 agaaattgct gttatagtag cagctgttat atctgcaact ggctctgcta aaattactgc
    13081 aaaaagtttt tcattaaaga atgttggaag tataaatatt aaaggtatta aaagtacaat
    13141 ctttctaagt agagctaaaa ccaaagatat tgttgctttt ccaagtgcta aaaatgtctg
    13201 ttgacaagct atttgaatcc caaacataaa agcaccagca aaatatattt ttatactcca
    13261 actagtcata ctaagtaact gcggattctt attaaatata ctaacaaaaa atgcaggaaa
    13321 tatcattaat aaaagccata aaatagtaga atatgtaaaa catgacaaca aacacaactt
    13381 aaatgtcttt tttactctat caagttgacc tgaaccataa ttataactta ttattggttg
    13441 tgctccttgt gtaaccccca tattaggaag cataagaatt tgcattatac tgctcattat
    13501 agccattgaa cctactgcta aatctcctcc atacatttgt aatttactat ttaaggctat
    13561 aagtactaaa ctttctgtag attgcattat aaatggagag attcccaaac caagcactgg
    13621 taagatgata cttgcttttg gtatcatata cttctttttt attttaagta tacttttctt
    13681 tccaaagaga aacataagta cccaaatagc agaaacgcct tgtgcaatta tagtagctaa
    13741 tgcagctcct tttacaccca tattaaagcc aaatataaaa atcgggtcaa gtattatgtt
    13801 tattaaagca cctatagcaa ctgtcatcat tccagttgta gcaaaccctt gggtatttat
    13861 aaaagtattc atacccattg aaatctgaac aaacactgta cctattaaat aaatatttaa
    13921 atagtccatt gaatatccaa ttgtagattc acttgctcca aacatccaaa gtaaaggctc
    13981 ttttccaatc ttaaaaccta tagtcaaaag tattgctaaa atcaccagta cagaaaaact
    14041 gttactcatt attttctctg cctcatcatt gttttgctca cccattttta tagcagctaa
    14101 tggacctcct cccataccga ttaaataact acatgcagtt attataatta ttattggaaa
    14161 tgccactcca acaccagcca tagcaacttc tccattttcc attctaccaa taaaaatcct
    14221 atcgactatg ttgtataaaa catttacaat ttgtgcgata atagcaggtg tagcaagttt
    14281 aaataataat ttacccacac tttcactacc taagttagtg tttgaatttt ccattttaaa
    14341 acctcctcaa tccaataatt aaaatgtatc actaaaattt tattctatat aaaaatttca
    14401 ttttattagc agacaaattt agagtacttt ccctacaagt aatactatac tatatttctt
    14461 ttgccatagt aaacatttta gaactaactg aagttaaata ctttatctca ttttttattt
    14521 attattaaaa atttttcaca catactcata aaaaaactat ccaagtatat tacttagata
    14581 gttttatatt atatgtaaag aaagagctga aactataacc cctgataaca aattgccaag
    14641 aaatactccc ataaaagcat cttttattct catttttaat atggaagcta tagcagatgc
    14701 agtccacgtt cctgtagttg gcagtggtat acctacaaat agtattatac caattatcga
    14761 aacacttttt aatttcttca ttcttgagtt tatttttcta tcaattacat cagcaatccc
    14821 tttaaatagt ttcttccctc ttaaaaattg taatacatgt ctgaatgtca atatcaaggg
    14881 aatcgatacc aatgtagaac ctattacact aaatacataa acccatatag gatttaagcc
    14941 cattgcaata cctataggaa tggctcccct caattctgtt acaggaacca tagataaaat
    15001 taatatgtgt aaatatccca aactattccc tcctattcta agtgacatta agttatgaat
    15061 ttatttgctc tataacctca ccatcctttt tactaactaa aaatgcattt ttagtcaatg
    15121 aaagcattgg taaatcactc ttagagtctg aatatgcata tgaattttca taatcaatct
    15181 ctatcccaag tttacctaat acagccttta ttctttttac tttttcaatt cccttacagt
    15241 tttctccaat gaatttattt ttatatcttg aattttcata aaaaaactcc gtgcctataa
    15301 cctcgtctgc aagaccataa tacttaaaat atttcatata tgcatatgga gatgcagtta
    15361 tcataattat aacattatct tcttctttat ttttgtaaat aacctttttc atagattcgt
    15421 taattttttt cattatgcaa tcatcaaaaa acttttttaa atcttcttca ctaaaatcta
    15481 ctattggata aaagattgcc tcttttgcct tcttc
//
LOCUS       DAEPKC010000094        15325 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.094, whole genome shotgun sequence.
ACCESSION   DAEPKC010000094 DAEPKC010000000
VERSION     DAEPKC010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15325)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15325)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15325
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.094"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..1886
                     /locus_tag="KR294_002963"
     CDS             <1..1886
                     /locus_tag="KR294_002963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBH0241025.1"
                     /translation="LERDLTISPIKNLLKYLAINIILGILSFFAVQNMYLGVLLNFIA
                     LFIIGYVFSYDLKRAVYVPFGLMYIFMVSIPVGKSEFPMRLSALAVGAVIIMIAQFVM
                     NRNRMKNVGDKELISICDELLEKISLLKNTINDDSSIIKSSMRKIDSCNYRINSISKN
                     LKMVIFDNRKDDFYISIRGIDIMNILFSLERISLILERYKKDSKEFEDEDIKNILEES
                     SINSKSDVLVVATKEINYIKMCLENKDTITDKEILGFRDYVIAQDTKNINLKEIYSVL
                     ENLYEFLVDYKKVKSRDEKKAERKSKIPHEFKRLSIYKKNFNLNSIRFSYAVKIALAT
                     AVAGFIMDYFHLRDGRWIMLTVFSLTQPYAENCIQRSRKRIEGTFIGAVIFIVLFSII
                     KDSTLRSLIVLLAGYINSYVVDYRKLMVCVTVSALGSAVVMGDPNVLTISRISYVALG
                     AIIALIVNKFILPYDAKTGYQHVIEMYKGIVKNIIDEVNKSIENVADVYYIKNLLLIP
                     SLIEDRLMLINAIYKDKHQEDFLENQKLLISNMYNLYINVNKNKIKDEDVEKILRDTN
                     YISNYNVDKYDEGRSVILESIVNTKSLGDKIICLNLLQTLNGVKEMYRISNITKVSIK
                     EAA"
     gene            2101..2958
                     /locus_tag="KR294_002964"
     CDS             2101..2958
                     /locus_tag="KR294_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBH0241026.1"
                     /translation="MSKDVKVKRNKKYDTFSITMELERPLLYDEVENKDDKNNNRKFN
                     IKNKIFKGIGILFVLILLGFFIWINKTYEPQKLAKEALVSNSKVEVTVNENISFTPKG
                     RKVSKGLILYPGAKVEIESYAPLARKIAESGYEVVIVKMPLNLAILGTNKAQKVMDSY
                     NNIEHWVIGGHSLGGVAASNFARDNKLIEGVVFLASYPMGDELKELGKKVISIWGSKD
                     GVVNFKSLVESKQKLPDDTTYVEIEGGNHAQFGDYGKQKGDNDAIISQEKQLNITANS
                     IIKFLKNIS"
     gene            3055..3924
                     /locus_tag="KR294_002965"
     CDS             3055..3924
                     /locus_tag="KR294_002965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBH0241027.1"
                     /translation="MEYDMPLYRPPSEAYSLIIQVTLGCSHNKCTFCSMYKSKKFKIK
                     PLEVIKNEIDIFRRYYKHVERIFLADGDALIIPMEKLRDIILYIKEVFPECERITMYG
                     SPKSIEKKSDDELKELRKLGVKMIYLGLESGSNEVLEDIKKGFSSEQLIKVGRKVKKS
                     GIKLSATVIAGLGGTKKTHQHAVDTGKMLGAISPDYVGVLSLMVEPNTELYDLLKAGE
                     FTILEDKAVLQEIKEMIKNIDANEKIVFRSNHASNYANLKGVLPDDKQRLIDEIDYYL
                     SNQKLKREEYRRL"
     gene            complement(4295..4927)
                     /locus_tag="KR294_002966"
     CDS             complement(4295..4927)
                     /locus_tag="KR294_002966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CatB-related O-acetyltransferase"
                     /protein_id="HBH0241028.1"
                     /translation="MTIPSSNKVYPRSNDYQTVYLKNVITRENIEVGDYTIYNDFYND
                     PRDFEKNNVLYHYPINNDKLIIGKFCSIACNAKFLMTSGNHSMKSKSTYTFPIFYEEW
                     KLDINHITDAWDNKGNIIIGNDVWIGYDSIIMSGVNIGDGAIIGTRAVVTNDVPPYSI
                     VGGVPAKIIKKRFNNDTISKLLEIKWWDWPYKKIQSNIKHIQSGNIDKLV"
     gene            complement(4999..5352)
                     /locus_tag="KR294_002967"
     CDS             complement(4999..5352)
                     /locus_tag="KR294_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase DNA-binding domain-containing protein"
                     /protein_id="HBH0241029.1"
                     /translation="MSTEKRRDNKDRILRTGESQRKDGRYAYKYVYSFGKPQFVYSWK
                     LVPTDKPPKGKRDDISLRDKEKAIQNDLDDSIDTIGKKMTVCQLYAKKNGLRKNIRLN
                     TKKGRHYLMKILNKE"
     gene            complement(5430..5633)
                     /locus_tag="KR294_002968"
     CDS             complement(5430..5633)
                     /locus_tag="KR294_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HBH0241030.1"
                     /translation="MNNTDVPIWEKYTLTIEEASKYFRIGEKKLRKLADENLDSGWVI
                     MNSNRIQIKRKQFEKIVDTLDFI"
     gene            complement(6023..6253)
                     /locus_tag="KR294_002969"
     CDS             complement(6023..6253)
                     /locus_tag="KR294_002969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH0241031.1"
                     /translation="MKPTKEVLPFTIILLAVHGDVNAINGILKHFEHYIIRLSQKTLF
                     DEYGNPYIHVEEETKRMLGTKLITAILRFNLS"
     gene            complement(6255..6662)
                     /locus_tag="KR294_002970"
     CDS             complement(6255..6662)
                     /locus_tag="KR294_002970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBH0241032.1"
                     /translation="MVDEKTIEHQFDSFCKTVLRNYARDIYDENKRRNDYLVSLESLS
                     LAELSKLSILDDYDSNYICMVSYDYNIRIEDVLMAQAIGKLTKRKQDIILLSFFLNMT
                     NADIATLMDLAENTIHYHKTNALKELKELMEEH"
     gene            complement(7022..7471)
                     /locus_tag="KR294_002971"
     CDS             complement(7022..7471)
                     /locus_tag="KR294_002971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH0241033.1"
                     /translation="MELIEWNYAYITDLVEFANDKEIAKNLRDNFPHPYREQNARDFV
                     SFCLATPDVKQLSYAIFYQERAIGSISLTFEEDTSINKNAELGYWLARNYWGKGIATN
                     AVKEICKIAFEKYNLNKIHANVYSYNRGSSKVLEKCGFKIEEYCHNS"
     gene            complement(7485..8411)
                     /locus_tag="KR294_002972"
     CDS             complement(7485..8411)
                     /locus_tag="KR294_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241034.1"
                     /translation="MSDILSRITNKIGDKNIVDKLSALSKSDLNSLLLEVFDRQANTL
                     TATDILKSYQLNRFTIPSGIDPEEIHALESKLLRKAFNMDIKTIMLSPSAPLGSCSVF
                     GSVDQYNVVSALRGTETLADPSNMLAIIIADKLKRKEENNTIPIHMATTARVIRAQNF
                     VGKGLYSHFGLYCMVSSGIDTGSYTCEKMLLEKHLNYYKDILSEIENVRFSIILRKRN
                     GYKDNDGFFDRMVETIKLIFPNIELSIHNDDVDNNYYKGINFKLSVKQGNETVEIVDG
                     GFVDWTYQMLGNKKERCLISGIGLERFLVAVS"
     gene            complement(8536..8940)
                     /locus_tag="KR294_002973"
                     /pseudo
     CDS             complement(8536..8940)
                     /locus_tag="KR294_002973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433844.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="oxalate:formate antiporter"
     gene            complement(9090..9710)
                     /locus_tag="KR294_002974"
     CDS             complement(9090..9710)
                     /locus_tag="KR294_002974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBH0241035.1"
                     /translation="MHLIDFMNEDIKKKLVKKTYKKKETILFAEQENEYVILMIDGIA
                     EAFILNVKGNISTIHLYRSGSFFGEMEQFNDGKKPVEIVAFTDCNVYKLHRDDFLNWL
                     RGDFEATKFLIREISSKLVVNAELIEELSSLSVKERLLRCISLHYYRSELNLLTKKQL
                     ASEVNAPIRSINRAINECVQEHLIAYENKRFSVINQREVLKNLPTT"
     gene            complement(9809..11077)
                     /locus_tag="KR294_002975"
                     /pseudo
     CDS             complement(9809..11077)
                     /locus_tag="KR294_002975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331151.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            11169..11984
                     /locus_tag="KR294_002976"
     CDS             11169..11984
                     /locus_tag="KR294_002976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage integrase family protein"
                     /protein_id="HBH0241036.1"
                     /translation="MVKLSDAKSWAIRMSEDGCAYKSIDNYKRSLKASFFMAIQDDCI
                     RKNPFNFQLSDVLEDTTEPKIALTPEQEMGLLSFMESDKTYCKYYDDVVILLETGLRI
                     SELCGLTLELDMKNKAIMVDHQLLSDTKIGYYVEVPKTTQGKREIPMTERAYQSFERI
                     VERRKNAKAEPIIVDGYQNFLFLKQDGLPKQATHYQSMLRALVKKYNKTHEDKLPKIT
                     PHTFRHTLCTNMANKGMSPNILQYIMGHKNITMTLGYYAHGSFSSSRAEMERL"
     gene            12656..13423
                     /locus_tag="KR294_002977"
     CDS             12656..13423
                     /locus_tag="KR294_002977"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HBH0241037.1"
                     /translation="MKRKVQVKNITIGEGRPKICVPIIGKNKKDIIKEAKELKDACLD
                     IIEWRVDFFENVENIKEVKEVLYELRSYIHDIPLLFTFRSVVEGGEKLISRDYYTTLN
                     KEISNTGLVDLIDVELFMGDEVIDEVVNFAHKKEVKVIISNHDFNKTPKKEEIVSRLC
                     RMQELGADLPKIAVMPQNEKDVLVLLEATNEMFKIYADRPIITMSMSGMGVISRLCGE
                     IFGSALTFGAAKSVSAPGQISFKELNSVLNLLHKSIN"
     gene            complement(13751..14428)
                     /locus_tag="KR294_002978"
     CDS             complement(13751..14428)
                     /locus_tag="KR294_002978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241038.1"
                     /translation="MIVIEGSDKFKIAKEYIDVEYTLFSKVTFRYEKLKFKDNAELEK
                     IKMFKYKNGYIPNKLNLSFGYGFSSYKKQIIRETVDTLRLTEIFSSENIEDIKFIKDG
                     TKKLEISIEKVVKFKRRKKRNYVCCYCPDMYRDIKLDKESINKIYNRKIKIEREVNIF
                     EDEDVIINKKVLKFPKSWTKNMQKYWLSENKYPIHSTVIDDDRYKCCNVQYTKNRVII
                     LYYIYNH"
     gene            complement(14578..14895)
                     /locus_tag="KR294_002979"
     CDS             complement(14578..14895)
                     /locus_tag="KR294_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0241039.1"
                     /translation="MNYIGKRLKEERKKANLTSKEFANMVGVSPWYITQIESGKKNPS
                     LKTFIKFVNILNISADVLIKDITSTGKTYLENDINEELKDLNSRELNLISQIIDIIKK
                     NKI"
     gene            complement(14917..15255)
                     /locus_tag="KR294_002980"
     CDS             complement(14917..15255)
                     /locus_tag="KR294_002980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0241040.1"
                     /translation="MANIGKIIGDRIKVYRTKLGYSQEFLAEKAGLHPTYIGQIERAE
                     TNTSINIIMKIATALDIPLELLFANIITTEGVDNSVPLECYEMINKLTEKEQIAMLEL
                     IKCIIKYKEI"
BASE COUNT         5444 a         2141 c         2303 g         5437 t
ORIGIN      
        1 tcttggaaag agatttaact atttctccaa ttaaaaattt actgaagtat ttagcaataa
       61 atataatctt aggaatacta tcattttttg cagtacaaaa tatgtattta ggagttttat
      121 taaattttat agcattattt ataatagggt atgtatttag ttatgactta aaaagagcag
      181 tatatgtacc ctttggtcta atgtatatat ttatggtaag tatacctgta ggaaaaagtg
      241 aatttcctat gagattgtcg gctttagctg ttggagcagt tataataatg attgctcaat
      301 ttgttatgaa tagaaatagg atgaaaaatg tcggagataa agaactgata tctatatgtg
      361 atgaattatt agaaaaaatt agccttttaa aaaatactat taatgatgat agttctataa
      421 ttaaatctag tatgagaaaa atagatagct gtaattatag aataaattct atatctaaaa
      481 atttgaaaat ggttattttt gataatagaa aagatgactt ttatatcagt attagaggta
      541 tagacataat gaatatttta ttttcattag aaagaataag tttaatcctg gaaagataca
      601 aaaaggatag taaagaattt gaagatgaag atataaaaaa tattttagaa gaaagtagca
      661 taaatagtaa atcagatgtt ttagttgtag caacgaaaga aataaactat attaagatgt
      721 gtttagaaaa taaagatacc ataactgata aagagatatt aggatttaga gattatgtta
      781 ttgctcagga tactaaaaat ataaatttaa aagaaattta tagtgtttta gaaaatttat
      841 atgagttttt agtagattat aaaaaagtaa aatcaagaga cgaaaagaaa gctgaaagaa
      901 aatcaaagat acctcatgaa tttaaacgac tatcaatata taagaaaaac tttaatttaa
      961 attctataag attttcttat gcagtaaaga ttgctttagc tacagctgta gcgggtttta
     1021 ttatggatta tttccattta agagatggaa gatggataat gttaactgtc ttttcattaa
     1081 cacaacctta cgcagaaaat tgtatacaaa ggtctagaaa aagaatagaa ggtacattta
     1141 taggagctgt aatatttatt gtattatttt caataataaa agatagtaca ttaaggtcgt
     1201 taatagttct tttagcaggg tatataaact cttatgtagt tgattataga aaattaatgg
     1261 tatgtgtaac tgtttcagct cttggttcag cagtagttat gggagaccca aatgttttaa
     1321 caataagcag gatttcatat gtagcattag gagcaattat tgcattaata gtaaataagt
     1381 ttatattacc atatgatgct aaaacaggct atcaacatgt tatagaaatg tataaaggaa
     1441 tagttaaaaa tataattgat gaagtcaata agtctataga aaatgtagct gatgtttact
     1501 atataaaaaa tttattattg ataccatcac ttattgaaga tagacttatg ttgataaatg
     1561 ctatatataa agataaacat caagaggatt ttttagaaaa tcagaaatta ctaataagta
     1621 atatgtataa tctatatata aatgttaata aaaataaaat aaaagatgaa gatgttgaaa
     1681 aaatattgag agataccaat tatatttcaa attacaatgt agataagtat gatgaaggaa
     1741 gaagtgtaat tttagagagt attgtaaata ctaaaagtct aggtgacaag ataatatgtc
     1801 taaacttact gcaaactcta aatggtgtca aagaaatgta tagaataagt aatataacta
     1861 aagtttcaat aaaagaagca gcttagatat taaattatag aatagccata tatttaaaat
     1921 aaagtatatg gctatttgtt ttataaaata ctaaaagaaa ataatatata aaaaacaaaa
     1981 aacatatatt tatgaatttt atatgaaaat agttaaaata ttgatttttt tcattggttg
     2041 aaaaaacaat ttacttagga taaactataa tagtattcaa atattatggg ggttagattt
     2101 atgagtaaag atgtaaaggt aaagcgtaat aagaaatatg atacatttag tataactatg
     2161 gaacttgaga gacctttact ttatgatgag gttgagaaca aagatgataa aaataataat
     2221 agaaaattta acataaagaa taagatattt aagggaatag gtatactatt tgtattgatt
     2281 ttgcttggct ttttcatatg gataaataaa acatatgaac ctcaaaagct ggcaaaagaa
     2341 gctctagtca gcaatagtaa agttgaagta actgtaaatg aaaacatttc atttacacca
     2401 aaaggaagaa aagtttctaa aggtttaatt ttgtatccag gagctaaagt agaaatagaa
     2461 tcttatgctc cacttgcaag aaaaatagca gaaagtggat atgaggttgt aatcgtaaag
     2521 atgccactta atctagctat acttggaact aataaggcac agaaagttat ggattcttac
     2581 aacaacatag aacattgggt aataggaggt cattcattag gaggagttgc agcatcaaat
     2641 tttgcacgtg ataataaatt aattgaaggc gttgtatttt tagcttctta tccaatgggt
     2701 gatgagttga aagaattagg aaaaaaagtt atatctatat gggggagcaa agatggagta
     2761 gtcaatttta aaagtcttgt agaatcaaaa caaaaacttc ctgatgatac aacttatgtt
     2821 gagattgaag gaggaaatca tgcacaattt ggagattatg gaaaacaaaa gggagataat
     2881 gatgctatta taagtcaaga aaaacaactt aatattactg ccaatagtat cattaaattt
     2941 ttaaagaata tatcttaaac taaaatttaa aaaatataat tttataagtt attatttaaa
     3001 gtaaatatta ataatataat agaatgaata ttttattaca agggggattt taatatggaa
     3061 tacgatatgc cactttacag accaccaagt gaggcttata gtcttataat acaagtcaca
     3121 ctaggatgtt ctcataacaa atgtacgttt tgtagtatgt acaaatctaa aaaatttaaa
     3181 ataaagccac tagaagtaat aaaaaatgaa attgatatat ttagaagata ttataagcat
     3241 gtagaaagaa tattcttagc agatggagat gcattgataa taccaatgga gaaattaaga
     3301 gatattatct tatatataaa agaagttttt ccagagtgtg aaagaattac tatgtacggc
     3361 tctcctaaat ctatagagaa aaaatctgat gatgaactta aagaattaag aaaacttggt
     3421 gttaaaatga tttatctagg gcttgaaagt ggaagcaatg aagtattaga agatattaag
     3481 aaaggtttta gtagtgaaca attaataaaa gttggtagaa aagttaaaaa aagtgggatt
     3541 aaattatcag ccactgtaat agcaggtctt ggaggaacta aaaaaacaca tcagcatgca
     3601 gttgatacag gaaaaatgtt aggagcaatt tcaccagatt atgtgggtgt acttagttta
     3661 atggtagaac ctaatactga actttacgat ttacttaagg caggagagtt tacaatacta
     3721 gaggataagg ctgtgttaca agaaattaaa gagatgataa agaatataga tgctaatgaa
     3781 aaaattgtat ttagaagtaa tcatgcatca aattatgcta atttaaaagg tgtattacct
     3841 gatgataaac aacgtctaat tgatgaaatt gattactatc taagtaacca aaagctaaaa
     3901 agagaagaat atagaagact atagtttttg atatatcaat ctatattgat aggtaaatac
     3961 taagattatt tagatacaaa aaatcatgct acattaatag ttgcttacta ttgatgtagc
     4021 atgatttttt tattaaaaaa caaaatggta tattcatata taatatatca ataataatga
     4081 aaatgtgaac tagtttaata gaattttacc tattataata aaaacaggaa tttaaataat
     4141 aaaaagtaaa gtaacttttt attaagtaac tttacttttt attttattta atgttgtatt
     4201 aaatttatat atattaaaat aatatacaaa ttttgaaaaa gctcttataa aatgattatt
     4261 aaagtaaagt ttaatataaa taaattataa aatattaaac taatttatca atatttcctg
     4321 attgaatatg cttaatgttt gattgaattt ttttatatgg ccaatcccac catttaattt
     4381 ctaataattt tgaaattgta tcattattaa atctcttttt tataattttt gcaggtactc
     4441 ctccaacaat agaatacggt ggaacgtcat tagtaactac tgctcttgtt ccaataattg
     4501 caccatcacc aatatttaca cctgacataa ttatagaatc ataacctatc cacacatcat
     4561 ttccaattat aatgttaccc ttattgtccc aagcgtccgt tatatggttg atatcgagtt
     4621 tccattcttc ataaaagatg ggaaaagtat atgtggattt tgatttcatt gagtgatttc
     4681 cactagtcat tagaaatttt gcattacatg ctattgagca aaacttacca attattaatt
     4741 tatcattgtt tatagggtaa tgatacaata cattgttttt ctcaaaatct cttgggtcat
     4801 tataaaagtc attatatatt gtgtaatctc caacttctat attttccctt gttattacat
     4861 ttttaagata tacagtttga taatcattac ttcttggata taccttattt gaacttggaa
     4921 tagtcatatt taaatctctc ctttaatata tattatgttt ttgactattc cactactaca
     4981 atacatctct tcacagaatc actccttgtt aagaatcttc ataagataat ggcgtccttt
     5041 tttagtgtta agtcggatat tctttcttag tccattcttt ttagcgtata actgacaaac
     5101 tgtcattttc ttaccaatag tgtcaatgct atcatcaagg tcattttgta ttgctttttc
     5161 cttatccctt aatgatatat catcacgttt tccctttggg ggtttatcag taggtacaag
     5221 tttccaagag taaacaaatt gtggtttacc aaatgaatat acatacttat atgcgtatct
     5281 tccatctttt ctctggctct ctccagttct taaaattcta tctttattat ctcgtctttt
     5341 ttcagttgac atgataagaa gctcctctca ataaccgaat tgagcttgat acgtcatatg
     5401 aatattataa catataaggc tcaatttcat tagataaagt caagtgtatc aacgattttc
     5461 tcaaattgtt ttctctttat ttgaatgcga ttgctattca taatgaccca gccagaatca
     5521 aggttttcat cagcaagttt acgtaatttt ttctctccaa tacgaaagta ttttgacgct
     5581 tcttcaatcg tcaaggtata tttttcccaa ataggtacat cagtattgtt catagaatgt
     5641 atcactcctt tctatgttcg tagttcagaa gtagatagat ggctttggta agctccattg
     5701 gtattttaac caatcccatt cttatgggca gaaccgtgtc atacaggtgt atcattatac
     5761 tgtggtacag gttacggcaa aacaaccgtt ccaaaggtta ttcacaaatc actatatagt
     5821 agctctcttg attaaggtca tggcgtatag tatttgttgg ctatctgtat cacaaacgta
     5881 tctatctact ttattcagtt gtcaaagaac agtcggcatt gatttgtcta taaaaaatca
     5941 caatagctta tgggctttta tagacaaata attagtgatt ctccatgtac caaatagctt
     6001 gatacatgga gagagggcga gattaagaca aattaaatct caaaatagca gtgattagtt
     6061 ttgttcctag cattcgcttt gtttcttctt ctacatgaat atagggattt ccgtattcat
     6121 caaataaagt tttctgtgaa agacgaatga tatagtgttc aaaatgttta agtattccgt
     6181 ttattgcatt tacatcgcca tgtacagcaa gtaaaataat tgtaaaaggt aatacttctt
     6241 tagtaggttt catttcaatg ttcctccatg agttctttca actcttttag tgcatttgtt
     6301 ttgtgataat gtatggtatt ttctgctaaa tccatcaatg ttgctatgtc agcatttgtc
     6361 atgttgagaa agaatgaaag tagaattata tcttgttttc tttttgtaag ttttccgatt
     6421 gcttgtgcca ttaatacatc ttcaattcgt atgttgtagt cgtaagaaac catacagatg
     6481 tagttagaat cataatcatc taaaatactc aatttactta attctgcaag tgacaaagat
     6541 tcgagagata ccaaataatc atttctgcgt ttattttcgt cataaatatc tctagcatag
     6601 ttacgcaaaa ctgttttaca gaaactgtcg aattgatgtt caattgtctt ttcatcaacc
     6661 ataagatttc accctctttc catcgcaagg agttaaataa ccttgcttac tcctatcacg
     6721 gtgggagggc gttaaatctt cgataaattt caaaaaaaag agaaaaaaat acacactctg
     6781 cctatagggc aaaaatgtgt attctttaaa acgtatttaa tttatattgg ttgtaagcca
     6841 ccaccatatt gatgtatgga aatatgcatt ggctagcttt tcataaaaat acaaagatgc
     6901 ataagaaatt aatagagggg aaaaacttat tctgttatta aaaagtaggt taattctaat
     6961 aaatgctatt gcggtcgaat taaactatat acatggcaat caatcatgtt tctattcttt
     7021 attatgaatt gtgacagtat tcttcaatct taaaaccaca tttttccaat actttacttg
     7081 accctctatt gtaggaatat acattagcat gaattttgtt aaggttgtat ttttcaaagg
     7141 caattttgca tatttctttt actgcatttg ttgctatccc tttgccccaa tagttcctag
     7201 caagccagta acctaattca gcatttttat taatagaggt atcttcttca aatgttaggc
     7261 tgatacttcc aatagccctt tcttgataaa aaatagcata gctaagttgt ttaacatctg
     7321 gagttgccaa acaaaaacta acaaaatctc tagcgttttg ctccctataa gggtggggga
     7381 agttgtcacg aagattcttt gcaatttctt tatcattcgc aaactcaact aaatcggtaa
     7441 tataagcata attccactct ataagttcca tttttcttct ccttttatga aacagctaca
     7501 agaaatcttt ctaagccaat accacttatc aaacagcgtt cttttttatt tccaagcatt
     7561 tgataagtcc agtcaacaaa tccaccgtca actatttcaa cggtttcatt tccttgtttg
     7621 accgataatt tgaaattgat acctttataa taattattat caacatcatc attatgaatt
     7681 gataactcta tattaggaaa aataagtttg atagtttcaa ccattctgtc gaaaaatccg
     7741 tcattatctt tgtatccgtt tcttttgcgt agaataatag agaaacgaac attttctatt
     7801 tcacttaata tatctttata atagtttaag tgcttttcta acaacatttt ttcacaagtg
     7861 taagaccctg tatctatacc agatgaaacc atacaatata agccaaaatg tgaatataaa
     7921 cctttaccta caaaattttg tgctcttatt accctagcag tagtagccat gtggataggt
     7981 atggtattat tttcttcttt tctttttaat ttatcagcaa taattattgc caacatattt
     8041 gaggggtctg caagtgtttc tgtccctcgt agagcactta ctacattata ttgatctacg
     8101 gagccaaaaa cgctacagct acctaatgga gcagagggag aaagcataat cgtcttgata
     8161 tccatattga atgcttttct caataatttt gactccaaag catgaatttc ttctggatct
     8221 ataccgctag ggatagtaaa tctatttagt tggtatgact ttagaatatc agttgcagtt
     8281 aaagtatttg cttgtctatc aaacacttct aatagaagtg agttcaaatc tgattttgat
     8341 agagctgata acttatcaac tatattctta tccccaattt tatttgtaat tctacttaaa
     8401 atatcactca tagttatcct ccatactgtt actttcaaaa taattataga atggttacaa
     8461 caactaatct aggtcatttg accaaaaatg aaaaaacact gaatatttac tattcaatat
     8521 ttttttactt tgggtttatt tgattaaatc ttgaaaatac tgtaatgcaa ccctttcagc
     8581 ttcaaccttt cggacaatag gactttgtga taattcctct cttaactcaa gatacaggtt
     8641 gatagtagcc tgcaatgcat taacacagct tttatattca tggttagcaa ccgtcttttc
     8701 taatgcttca atatattggg gtgcgtccaa ttcaattttt ctaactccac gaggtaattt
     8761 acctaagaga agctgtatta atggggcaag tactgattgt cttaaaaaag ataaaaaatc
     8821 aattgtttca aatagttctc tacgtccaat cttagtgcaa gcgtaatgaa cccaaatcca
     8881 aaatctatct tcaatccact gtaagtctgg agttgggaag tatgcttctt ttttagtata
     8941 acacctctca ctttctttta ttagctatca atccaacata attatgcata ggagtattat
     9001 ataatgaaaa aataaaaaaa aataggtcac ttgacccgaa ataaaaaagc attgaataat
     9061 tattattcaa tacttttttg aaattatact tatgttgtag gaagattctt taatacctct
     9121 cgctgattaa ttacactaaa tcttttgttt tcataagcaa ttagatgttc ttgtacacat
     9181 tcatttatag cacgattaat gcttctaatt ggagcgttta cttcgctagc aagctgtttt
     9241 ttggtaagca gatttaattc acttctataa tagtgtaagg atatacacct cagaagtcgt
     9301 tctttaacac ttaaagatga taattcttca attaattcag catttacaac taatttacta
     9361 gatatttctc gaatcagaaa ttttgtagct tcaaaatctc cccttaacca gtttaaaaaa
     9421 tcatctctat gaagtttata tacattacaa tctgtgaaag cgacaatttc aacgggtttt
     9481 ttcccatcat taaattgttc catttctcca aaaaaactac cacttctata aagatgaata
     9541 gttgagatgt ttcctttcac atttaagatg aatgcttctg caataccgtc aatcataaga
     9601 attacatatt cattttcttg ctcagcaaaa agaatagtct ctttcttttt atacgttttt
     9661 ttaacaagct tctttttaat atcttcattc ataaaatcaa ttaaatgcat attcatccct
     9721 ccttaccaaa tctttgatta aattatatca tctttcaatt agttaggtaa gatagtaaaa
     9781 atatatttac atagaaacta ttccattatt attttccagt tgtcattttt ctgcaaagta
     9841 agctcaaact gagaaagctg ttgacaatag aactagtagg aatatatgag cgaaccattt
     9901 cagtattcaa ctgttgtagg ttttcagtca gataattctt caaacgttca attcgtttgt
     9961 cctgtgaatc ttgcgatgct ctaaccagtt tcatagatag cgttttacct tgtgccacct
    10021 gcaaaaaaga ccatgcttcg tcaaggtcaa ctatcttgaa gctagagcgg tcagtatgaa
    10081 taaagtctaa tgcaaaggta ctaataacaa tcaacatagc aacactaaga agttctattg
    10141 ttgtatattc ttcaaagcta gtgttggcat ctggcaatac gaggtcagca acttgaataa
    10201 tattcagctg tttctccaag ctgatagact gcttcacatt tccgtcacca aacagtagat
    10261 gtgcaaaatc atagtctaca aaactttcga tatggtcggc tatgctgtta ctgatagaag
    10321 tatcttcttt tcgtaattca tcaatgacaa gtaataaccc tcgctgttca ctttgggtta
    10381 cattgcggat tgcttttcta agcactggga acttatcact gtcacgactg gagataccag
    10441 caaggaatgt taggatatca atcgctaaac tttcagaatc atttttacgg ctcaaaatga
    10501 cgtaagggtc aagcaatcct ttgttttcat cattactggt taaattgaca atgtttatct
    10561 catgggctat ttctggtagc gtttctttcc atttgccgcg ttctgcttta gggtcaacta
    10621 tgaccgcctg tccgccgaat agtaccgcat agtaaacaag catattgtta ctgaataatt
    10681 taccaccacc caatgaaccg ataaacgcag acgctaacac attggtaata gaacccttta
    10741 cccattgact agcaagggca ggttttagat agacattctt tccagtgtcc agattgtagc
    10801 caagatagat atcctcatgt tcgccaaggg tttgtgtcgc tccaaaacca agtccagcca
    10861 aaaaatccga agtgacatat tgaatataat cattgatgta acgtttgctg acaggaataa
    10921 attcgccatg caatcccaac atatccccaa agggacgcac gagcttgagt gataagtcgt
    10981 cgtaaaagtc tttgacttca tcacaacgcc tttttagctc gtcaagatcc tttgtagata
    11041 cacggacaac atagctaagt ttatacatag attctttaca gttaaaagtc tgtttttaaa
    11101 aaaatgtata aattataaat caaaatatag atactatcaa tgacccacta ggtgcaaaaa
    11161 gcattgatat ggttaaatta tcagacgcta aaagctgggc tatccgaatg agtgaagatg
    11221 ggtgtgctta taaatccatt gacaattata agcgctcact gaaagcgtcg tttttcatgg
    11281 caattcaaga cgactgtatt agaaagaatc catttaattt tcagttaagt gatgttttgg
    11341 aagatacaac agaaccaaaa atcgctctaa caccagaaca ggaaatgggc ttattatcct
    11401 ttatggagag cgataagact tattgtaaat attatgatga tgttgttatc ctcttagaaa
    11461 caggactacg catttctgaa ttatgcggtt tgactttaga attggatatg aaaaataaag
    11521 ccattatggt agaccatcaa ttgttgagtg atactaagat tggctattat gtagaagttc
    11581 caaagaccac acagggtaag cgagaaattc caatgactga aagagcttat caatcatttg
    11641 aacgtatcgt ggaacggcgt aagaacgcta aagcagaacc aatcattgtt gatggttacc
    11701 agaacttcct atttcttaaa caagatggat taccaaaaca agcaactcat tatcaaagca
    11761 tgttaagagc gttagtcaag aagtataata agacccatga ggacaagcta ccaaagatta
    11821 cgccacatac ctttaggcat acactctgta caaatatggc taacaaagga atgagtccta
    11881 atatattgca atatattatg gggcataaaa acattactat gacgcttggc tattatgcac
    11941 atggttcatt tagttcttcg agagctgaaa tggaacggtt ataatcctag tagtatgact
    12001 agagtttact acttatttac tacttttgat ggcattctta tacggttaaa tgccaactta
    12061 tgcaaagtat cttccaaaaa gaaaatgccg atactccttg tagatacagg atatatcgac
    12121 atttaccaac ttatgaaaag ataatcaaat ttaatataag tttttcaaat aaaaagatac
    12181 caaattcttt ttcgagaatc tatataacat tacttaagct tggttggggt ataaacaatt
    12241 gagtagctac ttttgtatgg tgttcaactt tagtcaaaac tcttaagtaa tgcaaatgat
    12301 ttagattcat taatattcaa tctcttcata agtagtgaaa ttcgagttat ttctgcataa
    12361 ttatactatg atttatagat taattctatt agcatccaga ataatattgt ttatatgagt
    12421 aaaatttaaa gaatattgtg aaaattatag gatgttaaaa taaatttagg taaaaaagaa
    12481 gtgtttgtat attatagagt accttttcta aaatatgtgg gattgtttta agaattagaa
    12541 taaaaattat ttttaaatta gtatttttat aatgtatagt atttttaatg tataattaaa
    12601 ttgtgcagaa aatagaattt aaagtcctat agaatttctg attatggagg agaatatgaa
    12661 aagaaaagtt caagtaaaaa atattactat tggagaaggt agacctaaaa tttgtgtacc
    12721 aattattggg aaaaataaaa aagatattat aaaagaggct aaagagttaa aagatgcatg
    12781 tttggatatt atagagtggc gagttgattt ttttgagaat gtagaaaata ttaaagaagt
    12841 taaggaagtt ctctatgaat taagaagtta tatacatgat atccctttat tattcacatt
    12901 tagaagtgta gtagaagggg gagaaaaatt aatatcaaga gattattata ctactttgaa
    12961 taaagaaatt tctaatacag gtttagtaga tttaatagat gtagagttat ttatgggaga
    13021 tgaggtcata gatgaagtag ttaattttgc tcataaaaaa gaagtgaaag taattatatc
    13081 taatcatgat tttaataaaa ctccaaaaaa agaagagatt gtatctcgtt tatgtagaat
    13141 gcaggaattg ggcgcagatt tacccaaaat agctgttatg ccgcaaaatg aaaaagatgt
    13201 gttagtgcta cttgaagcta caaatgaaat gtttaaaatt tatgcagata gaccaataat
    13261 aacaatgtca atgtcaggaa tgggtgttat aagtagattg tgtggtgaaa tatttggttc
    13321 tgcattgact tttggagctg caaaaagtgt ttcagcacca gggcaaatat catttaaaga
    13381 gttaaattca gtacttaatc tattacataa gagtattaat taaattaatt atatagaaat
    13441 attagacggt atttttgaag atataaatta aatataaaaa acttttcaga tagtaaaatt
    13501 taaattgggc aattatatct gaaaagcaac tatttagtgt gtattttgaa agtgatatag
    13561 aaaatcttat aaatcaacta tggcatattt aaaatatgcc attaaaacct actagacatt
    13621 agattataga tggtatacta gcatttctat tatttataga tagtaagttt tcataataac
    13681 tgttttatct aaagtagaag atatatttgt attatgtata tttgtcatta tttttttgta
    13741 attatgtata ttaatggtta tatatgtaat ataatattat cactctattt tttgtatatt
    13801 gtacattaca acatttatat ctatcatcat caattacagt agaatgtatg ggatacttat
    13861 tttcacttaa ccaatatttt tgcatattct ttgtccaaga ctttggaaac ttcaatactt
    13921 tcttgtttat tataacatcc tcatcttcaa aaatattaac ttctctttct atttttattt
    13981 ttctgttgta tatcttattg atagattctt tgtcgagttt tatgtctcta tacatatcag
    14041 ggcaatagca acaaacataa tttctttttt ttcgacgttt aaatttcaca actttctcta
    14101 tgctaatttc taattttttt gtaccatctt ttataaattt aatatcttct atgttctcgc
    14161 ttgaaaaaat ttctgtcaat cttaaagtat ctacagtttc tctaattatt tgctttttat
    14221 aagaagagaa tccatatcca aaagaaaggt ttaatttatt agggatgtag ccatttttat
    14281 atttaaacat cttaattttt tccaattcag cattatcttt aaatttcaac ttttcatacc
    14341 taaaagttac tttgctaaaa agagtatatt ctacatcaat atattctttt gcaatcttaa
    14401 atttatcgct accttcaatc acaatcatag cctatctcca atcgttttat attaaaataa
    14461 ggccatagaa catggtctaa tagtactcat tagcactata agacaatgtt aacacaaaaa
    14521 gacaaaaaaa ggttatttat ttcaaataac cttttttttt atataaaata taaagaatta
    14581 tattttattc ttttttatga tgtctataat ctgtgatatc agatttagtt ctcttgaatt
    14641 taagtctttt aactcttcat ttatatcatt ttctaaatat gtttttccag tggaagtaat
    14701 atcttttata agaacatctg cagaaatatt taatatattt acaaatttta tgaatgtttt
    14761 aagacttgga ttctttttac cactttcgat ttgagttata taccaaggcg atactccaac
    14821 catatttgca aattcttttg aagttaaatt tgcttttttc cgttcttctt taagtctttt
    14881 acctatataa ttcattattg ttactatttc cctcacttat atttctttgt atttaatgat
    14941 gcactttatt aactctagca ttgcaatttg ttctttttca gttaatttat taatcatttc
    15001 ataacattct aaaggtacag agttatcaac gccttctgtt gtaataatat ttgcaaataa
    15061 caattcaagt ggtatgtcta aagcagtagc aattttcatt ataatattga tagatgtatt
    15121 tgtctcagct ctttcaatct gaccaatata tgttggatgt aaacctgcct tttctgctag
    15181 aaactcttga ctatatccca attttgttct atagactttt attctatctc ctattatttt
    15241 tcctatattt gccaattatt atccctccac tttagattat attcatagtt taagttgttt
    15301 tatatagact atttatactt tttta
//
LOCUS       DAEPKC010000095        15233 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.095, whole genome shotgun sequence.
ACCESSION   DAEPKC010000095 DAEPKC010000000
VERSION     DAEPKC010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15233)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15233)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15233
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.095"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            367..1005
                     /locus_tag="KR294_002981"
     CDS             367..1005
                     /locus_tag="KR294_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241041.1"
                     /translation="MSNQRKDFDITNDMFQESIPITTKIILEDMPSNDELNHVFSKGC
                     ERKMKKRKIVLITLLLIGVLLLGSILYNLFLGKTANISMLKESWNFDIPIPNKEIEVF
                     DTQDSINGDGQSYFIQGFSEKNFKKVFNLKGGIVVSKDNINEIEKYIDKFKRDSVNIN
                     KSNKNKIEEDFKKYKLEVKKDDKYIYKRNYENYVVLIIKKDEQKLYSLIWNQ"
     gene            complement(1494..3254)
                     /locus_tag="KR294_002982"
     CDS             complement(1494..3254)
                     /locus_tag="KR294_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBH0241042.1"
                     /translation="MQEVEVIKAKNVLARQARGKAIERLRVAAYCRVSTDSEDQLNSY
                     KSQVQYYTDMIKKNKEWVLADIYADEAITGTQVTKREDFQRMINDCMNGEIDMVFTKS
                     ISRFARNTLDTLKYVRMLKERNIAVYFEDEKINTLTMDGELLLVVLSSVAQQEVENIS
                     ANVKKGLKMKMKRGELVGFQGCIGYDYHPEDKTITVNQEEAEIVRYIFNRYVDGAGGS
                     VIGQELESLGYKTKYGSSTWAPSTVIGIIKNEKYKGDILLGKTFTVDPISKRRLENMG
                     EEDKFYMKDHHEPIISEEVFEKAQEILNRRNKNRTTVGSGKREKYSRKYAFSCMLECG
                     FCGGTLTRRNWHSGSKYSKVIWQCVTATKKGKKFCKHSKGIPETAIEEAFVESYRLLC
                     DDNKDVLEEFLQRMDDTLSSSVVSKQLAKAEKEIDALEKKKSKLVDMRLEEIIDKETY
                     ESKYADLVSKQEQLVEERQKLQETSDNEKDIKKRLKEFKKTLEQNEVLDKFDRYVFES
                     IVEKVIVGGLDENGNVDPAQLTFVYKTGLKNSVDGAKFKTQRKNARGRHRTNELCSHD
                     SNEVDKMCSDSSNDTCGNCS"
     gene            complement(3317..3460)
                     /locus_tag="KR294_002983"
     CDS             complement(3317..3460)
                     /locus_tag="KR294_002983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBH0241043.1"
                     /translation="MNNIIRYSMQIAMLKQLLARKLISEKEYTLVKQRLMKDYKVLSD
                     ITA"
     gene            complement(3779..4018)
                     /locus_tag="KR294_002984"
     CDS             complement(3779..4018)
                     /locus_tag="KR294_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002592280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH0241044.1"
                     /translation="MMKSTKKCPSFSTISSAADGNEVAIEKILNHYDAYISKASLRPF
                     YDEHGNMYIVLDMELKGRIRAALIKVILGFEVKVK"
     gene            complement(4023..4439)
                     /locus_tag="KR294_002985"
     CDS             complement(4023..4439)
                     /locus_tag="KR294_002985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002592281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBH0241045.1"
                     /translation="MKPSSFEGAIRLQFDCLARKVVGRTVKNYDRELGRRARRETPFC
                     DLSEMELNQIGAMDEYCVEFTSFDVFGSEVHIYDERLCEAIKELTESRRNILLMSYFL
                     EMTDAEIAEVMEMERFSVCRNRLHTLKLIKDMYEEE"
     gene            complement(4436..4735)
                     /locus_tag="KR294_002986"
     CDS             complement(4436..4735)
                     /locus_tag="KR294_002986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBH0241046.1"
                     /translation="MKHLHIQQLSTIGSSLKKHLNSTEHNAPICGFLQHITGIICLAQ
                     DQYVCIALVLFYCIKLFQKIFAVGYQIPPFMVSVSAKRGRSLFALATFAGKGVRL"
     gene            complement(5786..5953)
                     /locus_tag="KR294_002987"
     CDS             complement(5786..5953)
                     /locus_tag="KR294_002987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002587909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241047.1"
                     /translation="MNWKELWMTLFGTTEWLGLNIGFWVAMAVVLLIVIVMNVVFWSM
                     KPKKDTKESYK"
     gene            complement(5966..8731)
                     /gene="mgtA"
                     /locus_tag="KR294_002988"
     CDS             complement(5966..8731)
                     /gene="mgtA"
                     /locus_tag="KR294_002988"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002571344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HBH0241048.1"
                     /translation="MNKKENRMAIRQTVEKAVIRDEQNRRIQFAATNPIKEVLKKLHT
                     TLRGLEVDEVSVSRAKYGTNKVTHEKKKSLAKRLVGAFINPFTAILFCLALVSTITDM
                     IFPYFSLFGSVPEDFDSLTVVIILTMVFISGTLRFVQESRSGNAAEKLLAMITTTCTV
                     TRRNYEKKELPMDDLVVGDIVHLSAGDMIPADVRILDAKDLFVSQASLTGESEPIEKT
                     PNVSAQKESVTDYTNIAFMGSNVISGSATAVVVCVGDHTLFGSMASAVAGEAVETSFT
                     KGVNAVSWVLIRFMLIMVPLVFFVNGITKGDWLAAFLFGVSIAVGLTPEMLPMIVTTC
                     LAKGAVSMSKKQTIVKNLNSIQNFGAIDILCTDKTGTLTQDKVVLEYHLNVNGEDDTR
                     VLRHAYLNSYFQTGYKNLMDLAIIHKTEEEEAADSRLIDLSENYVKVDEIPFDFTRRR
                     LTTVVQDNKGKTQMVTKGAVEEMLSICAFAECNGGVQPLTDDVRYRILETVDNLNDKG
                     FRVLAIAQKSNPSPIGAFGVKDECDMVLIGYLAFLDPPKESTADAIKALKDHGVITKI
                     LTGDNDKVTRTICKQVGLEVRNMLLGSDLEQMGDAELARVAESTDVFAKLTPDQKARV
                     VSVLRENGHTVGFMGDGINDAAAMKAADIGISVDTAVDVAKESADIILLEKDLMVLEQ
                     GIIEGRKTYANMIKYIKMTASSNFGNMFSVLAASALLPFLPMMSVHLIFLNLIYDLSC
                     TAIPWDNVDEEFITKPRKWDASSVGSFMIWIGPTSSIFDFTTYIFMYFVFCPLFVSNG
                     VLFNDLPAHFSGAELAMLQAQYIGMFQAGWFVESMWSQTLVIHMIRTPKLPFVQSRAS
                     APVTLLTMTGIIVLTIIPFTVFGTMLGFVALPAAYFAYLIPCILLYMTLATSLKKAYV
                     RHFGELL"
     gene            complement(8897..9208)
                     /locus_tag="KR294_002989"
     CDS             complement(8897..9208)
                     /locus_tag="KR294_002989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3784 domain-containing protein"
                     /protein_id="HBH0241049.1"
                     /translation="MDFTCIFFGILFTLAGFWLAFGKGYRHLSLWKNMPQEEKDKINI
                     VPLCRNVGEMIALNGIIFLMKGFLPGFSNHWFVFAIIAWLIVAGFDVWYIEKSVRYRN
                     Q"
     gene            complement(9455..10132)
                     /locus_tag="KR294_002990"
     CDS             complement(9455..10132)
                     /locus_tag="KR294_002990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018597221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HBH0241050.1"
                     /translation="MFYTDFILRIALSLTLGFLIGLERQLTGHPAGIRINVLICMGTS
                     FFTLFPMLYGSDQVFRVGSSIISGVGFLCSGVIFKDRGTVRGMNTAATLWCTAAIGIL
                     ASTGMYAMAITAATILIGSNLILRPFARKFHPITSSDESEKQYRISVTCQEKAEQDIR
                     LLLINSNSCKTLFLNNLESGDVVGDKVEIVAEYCSVGKSKNNILEGIVGQVLVIPEVI
                     SAGWEVL"
     gene            complement(10270..10773)
                     /locus_tag="KR294_002991"
     CDS             complement(10270..10773)
                     /locus_tag="KR294_002991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006566797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBH0241051.1"
                     /translation="MKKNISYIPMDSALEIWLLEKLLRDPPDSDCAKDLLSGIQEMIR
                     GEVSSLLLGASEESDWPVGTLSDRILAGDLEIYPRGRKVLIKGSEVNLTPKEFDILYF
                     LVQNKGEVFTKEQIYRAVWEEDYILDNSNIMAFIRKLRKKIEPAPDCPTYILTIWGIG
                     YKFNDQI"
     gene            complement(10789..13452)
                     /gene="mgtA"
                     /locus_tag="KR294_002992"
     CDS             complement(10789..13452)
                     /gene="mgtA"
                     /locus_tag="KR294_002992"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016440611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HBH0241052.1"
                     /translation="MSKATLFDSRIKKYAYCRTSEIYRDIGSSPDGLSIEQIGSMREK
                     YGANSFNGRKNDTTMQRLRRAFINPFHVILFVLGIVSLVTDVFVASNFARNATTAIII
                     FSMIVISGVIRLIQELRAKSAAAQLDRLVHESVTVRRDGKLIEIPGEELVVGDIVLFS
                     AGDRVPADIRLTKITDLFISQAAITGESAIIEKSCRKLSYGEQDTLTQLENLAFMATT
                     VISGKGEGIVLAVGKDTLYGGFTKPDSDDKNSFKKGADSIAWVMIRFMAILVPIVFIL
                     LGITDGKWMESFAFALSVAVGLMPEMLPMVITACLAKGSLAMSKKQTIIKDINAMQSF
                     GSMDVLCMDKTGTLTNESILLEYYMDIFGNENAEVLDLAYLNSCYHSGVCNTIDNAIL
                     ACNTMPGREAHYANLLTKFQKADEIPFDYARKFVSTLVQDSNGNSQLIMKGDIEHIFS
                     RCNHVEYRGKLLPMGQDARQSVSSVVGEMLQDGMKVIAVARKNVGAQKKITPDDEWGM
                     TLVGYLSFFDAPKQTAKESVTALKRLKVIPKILTGDQAAIAVSVCRRVGIYTERILTG
                     TQLDEMTDCELKKAVEHTHVFAELTPGHKVRLVSAMQDNGHSVGFLGDGVNDIPALNE
                     ANVGISVDTAVDAAKDAADVVLLQKDLNVLEQGVMEGRKTFTNMLKYIKITASSNFGN
                     IFSIICASAFLPFLPMTSIQILLLNLLYDTLCIVLPWDNVDEEEMLSPRDWSGKTLRQ
                     FMLSFGPISSLFDIVTFLFLYYFLCPMLCGGATYLQLTDPSLQLQYVALFQTGWFLES
                     MWTQVLILHFLRTSKIPFFQSRASAPVISITLVGIIAFTSLTFVGGASLFGLTKLPLW
                     YFVFLLLVVSLYMLLNSVAKYFYKKKYQELI"
     gene            complement(13545..13754)
                     /locus_tag="KR294_002993"
     CDS             complement(13545..13754)
                     /locus_tag="KR294_002993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241053.1"
                     /translation="MVKVKTKKKFVSTHMCQGEMPIYVRERYEKMLAVSIRAPNLEGM
                     VENFDKDLSRPNETDLIELKNAISK"
     gene            13704..14039
                     /locus_tag="KR294_002994"
     CDS             13704..14039
                     /locus_tag="KR294_002994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241054.1"
                     /translation="MTHMSADKLLLGFHLDHVSNLNELLRKVAHNNICIMSDRMTKVA
                     VWKPSVKTIQLVCMEYLNYIIDHSVIYEKIQCANWNGTEETNSIFNNSPSPLITLIYS
                     CDLQQNKTT"
     gene            complement(14238..15140)
                     /locus_tag="KR294_002995"
     CDS             complement(14238..15140)
                     /locus_tag="KR294_002995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBH0241055.1"
                     /translation="MFKKNKKQTENVKEKKVRTVKVGTHKKTVIALWVVLIASVSFGV
                     YKNFTAIDQHTTHEKEVIELRLQDTNGIENFVKNFAKSYYTWSNSKEAIDARTQAISG
                     YLTKELQDLNMDTIRTDIPTSSAITDVIVWSIEQSGTDTFSATYEVDQQIKEGEQTTA
                     VKATYTVKVHVDAGGNMVIIQNPTLAPAIEKSDYEPKTPEADASVDADTINDATAFLE
                     TFFKLYPTATEKELAYYVSGNVLESIGRDYLYSELVNPIFTVDGDNVKVKVAVKFIDN
                     QTKATQVSQFELVLHKESNWKIIG"
BASE COUNT         4825 a         3210 c         2462 g         4736 t
ORIGIN      
        1 ttaaatagcc ttatgttaga aagctaatta agatagattt ctagtattca taattttatt
       61 ttttatttaa aatacatata ataaagatgt aaatttgtat caaataataa atatgagaac
      121 ttaaattctc ttatctatgt gaaaataaac atctcttaaa atgaaattct gtaaatataa
      181 atgatttttt agtttgaagg attagattaa caaaattata aatttgcaaa taagctatat
      241 taaaaaatat aataattttt tatataactt attcttttat aacttttaat tttaaaagag
      301 gagaatgtat ataagagtat tcaatgtact agaaaaaatc aaaagaaata ttagaagaaa
      361 tggatattga gtaatcaaag aaaagatttt gatattacaa atgatatgtt tcaagaaagc
      421 attcctatca caacaaaaat tattcttgaa gacatgcctt caaatgatga attaaatcat
      481 gttttttcaa aaggttgtga acgaaaaatg aaaaagagaa aaattgtatt aatcacacta
      541 ctattaatag gtgttttgtt attaggaagt atcctatata atcttttttt aggaaaaaca
      601 gctaatattt caatgctaaa ggaatcttgg aattttgata taccaatacc taacaaagaa
      661 attgaagtat ttgatactca agatagtatt aatggagatg gacaaagtta ttttattcaa
      721 ggattttctg aaaaaaattt caaaaaagtt tttaatttaa aaggtggtat agttgtaagc
      781 aaagataata ttaatgaaat agaaaaatat attgataaat ttaaaagaga ttctgttaac
      841 attaataaaa gtaataaaaa taaaattgaa gaagatttta aaaaatataa gttagaagtt
      901 aaaaaagatg ataagtatat atataagaga aattatgaga actacgtagt tttaattata
      961 aaaaaagatg aacaaaaatt atacagttta atatggaatc agtaggtaca tatgtattat
     1021 taagaattat aaataataaa aataaatttt agtcaatata caaaaacctt ttaaattgtc
     1081 tggaaatcac ctcttcattt gttataaaaa catacaacaa atgaagaggt gattttatgg
     1141 ttttaaaaaa aataattata agtggatatg tgctttcaca tgtttatcaa catttgtaat
     1201 gcctatattt gctaatgaat tataaaaata ttaaataata ttcaactata gattatgtaa
     1261 attactctat gaaaaaaatg agttgtataa aatctggcta ctgtagattg actatttctt
     1321 ttaaaattac aattataata agttttatag aattaaaaat aaaactttag agatttttga
     1381 taacattgta gactaaattt gccaccgaaa tcgctttaca gtggcaaatc ggtggcaaat
     1441 acaatatatt attagtatat aatctatata aacattacta ttgtttgatt atcttagcta
     1501 cagtttccac atgtgtcgtt actactatcg gaacacattt tatcaacctc gttgctgtca
     1561 tgtgaacaca attcattagt cctatgccgt cctcttgcat ttttcctttg tgttttaaat
     1621 ttagcaccat ctacgctatt cttcaagcct gttttataaa caaaggtcaa ctgtgcaggg
     1681 tcaacatttc cgttttcatc aagtccacct acaattactt tttcaacaat gctttcaaac
     1741 acatagcggt caaatttatc aagaacctca ttctgttcca gagttttctt aaactctttc
     1801 aaacgttttt ttatgtcttt ctcattatca gaagtttctt gtaacttttg tctttcttca
     1861 acaagctgtt cttgtttact tactaaatca gcatatttac tttcgtaggt ttccttatca
     1921 ataatttctt ccagacgcat atccacaagt ttactttttt tcttctctaa tgcgtctatc
     1981 tccttttccg cttttgcaag ttgttttgac accacactac tactaagagt atcgtccatt
     2041 ctctgcaaaa attcttccag aacatcttta ttatcatcac ataataaacg ataactttct
     2101 acaaatgctt cttcaatagc tgtttctgga atacctttgc tatgtttaca aaatttcttt
     2161 cctttcttcg tagccgttac acattgccat ataaccttgc tgtattttga gccactgtgc
     2221 caattacgtc ttgttaaagt accaccacaa aagccacatt ctagcataca gctaaatgcg
     2281 tatttcctgc tatacttctc acgcttaccg ctgcctaccg ttgttcggtt cttatttctc
     2341 cgattaagaa tttcctgtgc tttttcaaaa acttcttcac taataatcgg ctcatggtga
     2401 tctttcatat aaaatttatc ttcttcaccc atgttttcaa ggcgacgttt ggaaatcgga
     2461 tcaacagtaa aagttttgcc taagagtata tcacccttgt atttctcatt cttaataatt
     2521 ccaataaccg tagatggtgc ccatgtggaa ctcccatact tcgttttata acctagactt
     2581 tcaagctcct gtccaataac agaaccacca gcaccatcaa cataacggtt gaaaatatat
     2641 ctgacaatct ctgcttcttc ttgatttaca gttattgtct tatcctctgg gtgataatca
     2701 tatccaatac aaccttgaaa acctaccagc tcgccgcgct tcattttcat tttcaaccct
     2761 ttttttacat tggctgaaat gttctcgact tcctgctgtg caacagaact aagaacaaca
     2821 agcaataact ctccatccat tgtaagtgta ttgatttttt catcttcaaa ataaacggcg
     2881 atatttctct cttttagcat acgaacatat ttcaatgtgt ctaaagtatt tctggcaaat
     2941 cttgatatgg attttgtaaa taccatgtca atttcaccat tcatacagtc atttatcata
     3001 cgctgaaaat cttctcgttt tgttacttgt gtccccgtaa ttgcttcatc agcataaatg
     3061 tcagctaaca cccattcctt gtttttctta atcatgtcag tataatactg aacttgtgat
     3121 ttataactgt ttaactgatc ttcgctatct gtacttacac ggcaatatgc agctacacgc
     3181 aaacgctcaa tggcttttcc acgggcttgt cttgccaaaa cattttttgc ttttattact
     3241 tcaacttcct gcatagtaca cctccttatt ttgtgttcct ttcatattgt tattgtacta
     3301 ctttaaaaaa cacaattcaa gcagttatgt cagaaagcac cttatagtct ttcatcagcc
     3361 tttgttttac aagagtgtat tctttttcag aaatcagttt acgggcaagc agttgtttta
     3421 acatagcaat ttgcatacta tacctaatta tattattcat taaaaccctc cttgcttttt
     3481 tatttatgga agtaatcaga cggcttcggc agctccactg gactttcacc attcccattc
     3541 tgatgggtga accgtgtcat acgggtgtat cattattcag atatacgagt catggcagca
     3601 acctttccaa agatcgcttg cggttcactg gcataatcgc tcgctgcttt ccccatttca
     3661 gtggtcgtgg cgttccagtc cgctggctcg tcgtatatca aacgtatctg attactgtat
     3721 tcacttgtca aagaacggaa aagagttaaa atgaggtggt agatactctc tgttatattt
     3781 acttcacttt gacttcaaac cctaagatta ctttaatcaa cgctgcccgt atcctgcctt
     3841 tcagttccat atcaagcacg atatacatat tcccgtgttc gtcatagaac gggcgtaggc
     3901 tggcttttga tatgtaagcg tcataatggt tcaaaatctt ttcaattgcc acctcgttac
     3961 cgtcagctgc agaactgatg gtcgagaatg atggacactt ttttgtagac ttcatcatgt
     4021 ttttattcct cctcgtacat atccttaata agctttaatg tgtgcagcct gtttctacat
     4081 acggaaaatc gttccatttc cataacctct gcaatttcag cgtcggtcat ttcaagaaag
     4141 taggacataa gcagaatgtt acgtcggctt tctgttaatt ctttgatagc ttcacataag
     4201 cgttcatcat agatatggac ttctgaacca aatacatcaa atgacgtaaa ctcaacgcaa
     4261 tattcgtcca tggcaccgat ctggtttaac tccatttcag ataaatcaca gaacggcgtt
     4321 tcacgtcttg cacgtctgcc aagctctcgg tcatagttct ttacagttcg tcctacaacc
     4381 ttgcgagcta gacaatcaaa ttgaagtctg atagcgccct cgaaagaaga tggtttcata
     4441 atctcacccc ctttccagcg aaagttgcta aagcgaaaag acttctacct cttttcgcac
     4501 taacactcac catgaaaggt gggatttgat acccaaccgc aaaaattttt tgaaaaagtt
     4561 ttatgcagta aaaaagcaca agggcaatac agacgtactg atcttgtgct aaacaaatta
     4621 ttcctgttat atgctgtaaa aaaccacata taggagcatt atgttccgta gaatttaaat
     4681 gtttttttaa tgaactaccg atggtcgaaa gttgttgaat atgtaagtgt ttcatacggc
     4741 tacccctaga gccgataaaa caagaccatc cagtaatttg tccaacgtta ggcaaaaata
     4801 aaacggcggc tatataaccg tcgtcttatt caaaagttca aaaagaacta aactaaaccc
     4861 tctaaagcag tatgtattta taatcagtct tgcaaaataa caaagtagaa ttgaaatata
     4921 aggtagcaat ccttgtgcat ctaataaact tataggggtt acagcagacc acggaataat
     4981 attttgtata ctttcagatc aatatagtcc aacaaaacca attcccgata tttagtaact
     5041 aaaaagtaaa ctagagtaga aaacatttct ttgcaaaaca caaataataa gtaatggact
     5101 cattgacaat agattgagaa atccagtttt ttagacttag atagattatc tcacttgtaa
     5161 atgatttaag ttctttgact tcatatatag cggtataatc tgtcaacgtg atcattacaa
     5221 accataatgc ctatataaca tactttccaa gcaaaaactt tattctatta gttggggaat
     5281 acaaaatatt tatcattgtg cgttcaacat attctttttg tataaaaatg taattacaaa
     5341 acaccactca atataagata gataataatt tgaataggaa ttatcaatct acgtaaccat
     5401 tcattacctg tcattgttgt tacaatagat ttgggattct gtttccatta cataattttt
     5461 ttatccttct ttcagatatc tcctcatttt atcgaagctt cttctacaga catacattcc
     5521 ataataaaat ctacctttga atattatttc acgatttcgt tatagacgcg taaacaaaca
     5581 ataaaaaacg aaatttcttt taagtaccat aatttttata tcgaaattac aattatccac
     5641 ttatatacag catttatagg taattcaatg ataaaaaaac acatacttta ctactaaatt
     5701 gccacaattg aatgcgcctt gatatgatag ggagattcca caataaaaaa ctgtgcatct
     5761 cccttgattc attcatactg atatcttatt tataagactc ttttgtgtct ttttttggtt
     5821 tcatggacca aaatactaca ttcattacaa taacaatcag caacacaact gccatagcca
     5881 cccaaaagcc gatattaaga ccaagccatt cggtagttcc aaaaagggtc atccaaagtt
     5941 ctttccagtt catcattcca cctccttaaa gcagttctcc gaaatgacgg acataggctt
     6001 tttttaaact tgttgccaaa gtcatataca gcagaataca tggaatcaga taagcaaagt
     6061 atgctgcagg caatgcaaca aatccaagca tagttccaaa cacagtaaac ggaataatgg
     6121 tcagaactat aattccagtc attgttagca aagtcaccgg agctgatgca cgactctgaa
     6181 caaaaggtag ctttggagta cgaatcatgt gaatgactaa tgtctggctc cacatagatt
     6241 ccacgaacca ccctgcttgg aacatcccga tatactgtgc ctgaagcatt gccagttctg
     6301 caccgctgaa atgagcaggc aaatcattaa ataatacacc attcgatacg aacaatggac
     6361 aaaatacaaa gtacataaaa atataggttg taaaatcaaa gatagaactg gttggtccaa
     6421 tccagatcat aaaacttcca acactggaag cgtcccattt acgaggtttg gtaataaact
     6481 cctcatccac attatcccaa ggaattgcag tacaggataa atcataaatt aagtttagaa
     6541 atataagatg aacactcatc attggtaaga aaggtagcaa agcagatgca gcaagcactg
     6601 agaacatatt gccgaagttg gatgaagcag tcattttaat gtacttgatc atgttggcat
     6661 atgtctttcg tccctcaata ataccctgtt ccaaaaccat cagatctttt tccaatagaa
     6721 taatgtcagc agattctttt gccacgtcca cggcggtatc caccgaaata ccaatatcgg
     6781 cggctttcat agctgcagca tcattaatac cgtcacccat gaaaccgacc gtatgaccat
     6841 tttcacggag aacagaaacc acacgggctt tctgatcagg ggttagcttt gcaaatacat
     6901 ctgtagactc tgccactctt gcaagctctg catcgcccat ttgttccaaa tcagaaccga
     6961 gaagcatatt gcgaacctct aatcccacct gcttgcagat agttcgagtc actttgtcgt
     7021 tgtcacctgt caaaattttg gttataacac catggtcttt cagagcttta atagcatccg
     7081 cagtagattc ttttggagga tcaaggaatg ccagatatcc aatcagtacc atatcacact
     7141 catctttaac accaaatgcg ccgattgggg aaggattact cttctgtgca atagctagta
     7201 cgcggaatcc cttatcgtta agattgtcca ctgtctccag aattctgtaa cgaacgtcat
     7261 cagtcagagg ctgcactcct ccattacact ctgcaaacgc acaaatagag agcatttctt
     7321 ccacagcacc ttttgttacc atctgggtct tacccttatt atcctgtacc actgtagtca
     7381 gacgacgacg tgtgaagtca aaaggaatct catctacttt cacatagttt tcagacaggt
     7441 caatgagacg cgaatctgcg gcttcctctt cctccgtctt atggataatt gccaaatcca
     7501 tcaggttttt atagccagtc tggaagtaac tattgaggta agcgtgacgc agtactcgcg
     7561 tatcgtcctc gccatttaca ttcagatggt attccagcac aaccttatcc tgggtcagcg
     7621 tgccagtctt gtcagtacag agaatatcaa tagcaccgaa gttctgaatg gaattgaggt
     7681 ttttaacgat tgtctgcttc ttgctcatgg aaacagcgcc tttcgcaaga caggttgtta
     7741 caatcatcgg caacatttct ggtgtcaaac caacagcaat agaaacgccg aataagaagg
     7801 ccgccaacca atcgcccttg gtgataccat tgacaaagaa caccagcgga accataatga
     7861 gcataaaacg aatcaatacc caagaaacgg cattgacacc cttggtaaag cttgtttcaa
     7921 ccgcttctcc agcaactgcg gacgccatag agccaaacag agtatgatcg ccaacacaaa
     7981 caacaacagc tgttgcgcta ccagaaatta cattactccc cataaaagca atgtttgtgt
     8041 aatcagtcac gctttctttc tgagcactta cattgggtgt tttttcaata ggttcactct
     8101 caccagtaag acttgcctga ctgacaaaca aatccttcgc atccaaaata cgaacatccg
     8161 ccggaatcat atctccagca gaaagatgca caatatctcc caccaccaaa tcatccatag
     8221 gaagttcttt tttttcatag tttctacgag taactgtaca agtggtcgta atcatggcta
     8281 acaatttctc tgctgcattt ccgcttctgg attcctgtac aaaacgaagc gtaccggaaa
     8341 tgaataccat tgttaaaatg attacaacag tcagggaatc aaagtcctct ggcacactgc
     8401 caaacagaga aaaatacgga aaaatcatat ctgtaattgt ggatactaaa gccagacaaa
     8461 ataaaatggc ggtaaatgga ttgataaatg cgccaaccag tcgttttgcc agagatttct
     8521 ttttttcatg agtgacttta ttggtaccat atttagcacg acttacggat acttcatcta
     8581 cttctaagcc acgaagtgtg gtatgaagtt tttttaaaac ttctttaata ggattggttg
     8641 ccgcaaattg aatgcggcgg ttctgttcgt cacggatgac tgctttttct acagtctgac
     8701 gaatagccat acgattttct tttttgttca ttggtcttac ctccttgaat tttcataggg
     8761 gcaaggaata ttatatgagc gacacggaat ctccaaattc tcatataata ttctctgcct
     8821 tcgtggactg acatcagagt ccatgtcttt cacctcacaa tcttaaaaaa atatctatgt
     8881 gaaacctcaa tgtggattat tggttgcgat agcggacact tttttcgata taccagacat
     8941 caaagccggc aacaatcagc catgcgatta ttgcaaatac aaaccagtgg tttgaaaatc
     9001 ccggcaaaaa tcctttcatt aagaatataa tcccatttaa cgcaatcatt tctccaacat
     9061 tacgacaaag cgggacaata ttaattttat ctttctcctc ctgcggcata tttttccaca
     9121 gggaaagatg acgatatcct tttccaaagg ccaaccaaaa gcctgcaaga gtaaataaaa
     9181 ttccaaaaaa gatacatgta aaatccatcg tttgttcctc ctttcaatgc ttaaacctgt
     9241 ttcttagttt tgtcagcttc agaagtttaa tgaagagcac aataatagta acagcaagaa
     9301 taaaccagat cacaatactc acctgatacc atatcttaaa gattaccatt ctttgttcaa
     9361 agaaattcca acccaaatag ctacataaga ttgtaaatac agggtagaaa gcaaaaagaa
     9421 ttgctcgttt caaatcttcg atttctctcc tcactcacaa cacctcccaa ccagcactaa
     9481 tcacttccgg aattaccaat acctgcccaa cgattccttc taaaatattg tttttggatt
     9541 ttccgacaga acagtattct gcgacaatct caaccttgtc accaaccaca tcaccgcttt
     9601 ccagattgtt caaaaagagc gtcttacagg aattgctgtt aatcagcaat aagcgtatat
     9661 cctgctctgc cttttcctga catgtaaccg aaatacgata ctgcttttca gattcatcac
     9721 tggaagtaat tgggtgaaac tttcttgcaa agggacgtag aatcaggttg gaaccaatta
     9781 aaatagtagc ggcggtgatc gccattgcat acattcccgt acttgcaaga attccaatcg
     9841 ctgcagtaca ccataaggtg gcagcggtat tcattccacg tactgtccct ctgtccttga
     9901 aaataacacc actgcataaa aaaccaacac cggatataat actgcttccg acacggaata
     9961 cctgatccga accgtagagc ataggaaaca aggtaaagaa acttgtaccc atgcagatta
    10021 acacattgat acgaatacct gcaggatgac cagtcaattg ccgttctaat ccaataagaa
    10081 atccaagtgt taaggagagg gcaattctca aaataaaatc tgtgtaaaac atatgaaaca
    10141 cctcccttta actactaaca gtatataaaa aatccaaata caatcctatg gctaaagtct
    10201 tgcgattttc ttgcgatttg gtaagaaaat agacggactg aaaccgaaaa tggtcttagt
    10261 ccgtctttgt catatctgat cattaaattt gtatccaata ccccagatgg tcaaaatata
    10321 tgtgggacaa tccggagcag gttcaatctt ttttcgcaac ttccggataa aagccataat
    10381 gttgctgtta tccagaatat aatcttcctc ccatacggca cgataaatct gttcctttgt
    10441 aaaaacttca cctttgttct ggacaagaaa gtacaaaata tcaaattcct ttggagtcag
    10501 gttgacttca gaacctttta tcagtacttt tctgcctctt ggataaattt ccagatcccc
    10561 tgccaggatt ctatctgaca gagtacccac tggccaatcg ctttcttctg atgctcctaa
    10621 caataacgaa gatacctctc cacgaatcat ctcctgaata ccagaaagta aatccttcgc
    10681 acaatcactg tccggtggat ctcttagtag tttttctaat agccagattt caagagccga
    10741 atccatcgga atataactaa tattcttttt catcatgaat gcctcctctt aaatcaactc
    10801 ttgatatttt ttcttataaa aatatttggc tactgaattc agcagcatat agagagatac
    10861 caccagcagt aaaaatacga aataccaaag aggtaatttc gtcagtccaa acaacgacgc
    10921 accgccgaca aatgtaaggg aagtaaaagc aataatcccc actagagtta tagaaatgac
    10981 cggtgcagat gccctgctct ggaaaaaagg aatcttggaa gttcgcagaa aatgtaaaat
    11041 caaaacctgt gtccacatag attccaaaaa ccatccagtc tgaaacagtg ctacatactg
    11101 aagttgcagg gaaggatctg taagctgcag ataggttgcc cctccacata gcatcggaca
    11161 taggaaataa tacaaaaata ggaaggtgac aatatcaaac agagaactga tcggtccgaa
    11221 agacagcata aactgtctca gtgttttgcc ggaccagtct cttggggaca gcatctcttc
    11281 ctcatctaca ttgtcccaag gaagcacaat acacaacgta tcatacagca gattcaaaag
    11341 cagaatctga attgaagtca taggcaggaa cggtaaaaag gcactggcac aaatgatgga
    11401 aaaaatattt ccaaagttag agctagcggt gattttaata tatttcagca tattggtaaa
    11461 agtttttcgc ccctccatta caccttgctc caaaacattc aagtcctttt gcagcaaaac
    11521 cacatcggca gcatcttttg ctgcgtccac tgccgtatct acagagattc ccacatttgc
    11581 ttcattcagt gccggaatgt cgttgactcc atcaccaaga aatcccacgg aatgaccatt
    11641 atcctgcata gcagagacaa gacgcacctt atgtcccgga gtaagctctg caaaaacatg
    11701 agtatgttcc acagcctttt taagttcaca gtctgtcatt tcatccagtt gagtaccagt
    11761 taagatacgc tctgtataaa tacccacccg gcggcaaaca gacacagcaa tcgctgcctg
    11821 gtcccctgtc agaatcttag ggataacttt taatcttttg agtgcagtta cagactcctt
    11881 tgctgtctgc tttggtgcat caaagaagga tagatagcca actagagtca tgccccattc
    11941 gtcatcagga gttattttct tttgcgctcc cacatttttt cgtgccaccg caatgacctt
    12001 cattccgtcc tgtaacattt cacctactac agaagataca ctctgtctcg catcctgccc
    12061 catggggaga agttttccac gatattctac atggttgcag cgtgagaata tatgttcaat
    12121 atcacctttc ataataagct gactattccc attgctatcc tgtacaagtg tactgacaaa
    12181 cttacgagca tagtcaaagg gaatttcatc agctttttgg aattttgtca gaagatttgc
    12241 gtaatgggct tcccgccctg gcatggtatt gcaggcaaga atggcattat caatggtatt
    12301 gcagacacca gaatgatagc agctattcag ataagcaaga tcaagaacct ctgcattttc
    12361 attcccaaaa atatccatat aatattccag caggatgctt tcattggtaa gtgttcctgt
    12421 tttatccata caaagcacat ccatgctacc aaagctctgc atggcattaa tatccttgat
    12481 aatggtctgc tttttgctca tagcaagact tcctttggca aggcaggctg taataaccat
    12541 aggaagcatt tccggcatca gacctacagc aactgacagg gcgaaagcaa aagattccat
    12601 ccattttcca tcagtaatcc ccagtaatat aaatacaatg ggaactaata tcgccataaa
    12661 acgtatcatc acccaggcga tggaatcggc tcctttttta aaggaatttt tatcatcaga
    12721 atccggtttg gtaaatcctc catacagggt atctttgcct actgccagta caatgccttc
    12781 cccttttcca ctgatgactg tggttgccat aaaagcgagg ttttcaagct gagtcagtgt
    12841 atcctgctct ccgtaactga gttttcggca gctcttttca atgatggcgc tctcgccagt
    12901 aatcgcagcc tgagagataa agagatccgt aatcttcgtc aatctgatat ccgccggaac
    12961 acgatcacct gcagagaata gtacaatatc ccctaccact aattcttcgc caggaatctc
    13021 tattaacttt ccatcacgcc tcactgtgac gctttcatga actaggcgat caagctgagc
    13081 agcagcgctc tttgctcgca gctcctgaat cagacgaatt acgccactaa ttacgatcat
    13141 ggaaaagatg ataatggcgg tagtagcatt tctcgcaaaa ttggatgcta cgaaaacatc
    13201 cgtaacaaga gaaacaatgc ccagaacaaa aagaatcaca tgaaacgggt taataaatgc
    13261 ccgtctcaac cgttgcatcg tcgtatcatt tttccgccca ttgaagctgt tcgctccgta
    13321 tttctcccgc attgaaccga tttgctcaat ggataaacca tccggagatg agccaatgtc
    13381 tcgataaatt tctgatgttc tacagtatgc gtattttttg atacgactat caaatagtgt
    13441 tgcttttgac acgaaacatc ccctccttta taagtataag taataacatt ttaacacagt
    13501 gttctgaaaa tgctatattt atattcttgc ttttttcttg caatttactt tgatatggca
    13561 tttttcagct cgatcaaatc cgtctcgtta gggcgagata aatccttatc aaagttttca
    13621 accattcctt ctaaatttgg agcacggatg gatacggcaa gcattttctc atagcgctct
    13681 cgcacataaa taggcatttc cccttgacac atatgagtgc tgacaaactt cttcttggtt
    13741 ttcaccttga ccatgtatca aatttaaatg aactacttag aaaagttgct cataataata
    13801 tttgtattat gagtgataga atgacaaaag tggcagtatg gaaaccgagt gtaaaaacaa
    13861 tacaattagt ttgtatggaa tatctgaact acataattga ccactctgta atttatgaaa
    13921 aaatacaatg cgcaaattgg aacgggacag aagaaaccaa tagtattttt aataattccc
    13981 cttcaccatt gattactctt atctattctt gcgatttaca acaaaataaa acaacataaa
    14041 ttttaaatac gttgactggc ataattcata tgtatagtaa gtctacaatt aagatgcgct
    14101 ttttctaatc caaatatatt aagaaaaaag ttttgcgaag ccattaatac tttgtttaag
    14161 atgtctttca taaatataaa gaataatgct cttaacaaaa gcgtgcaaat tcctaaagaa
    14221 atgcacgctt tcaataatta tcctataatc ttccaattgc tctccttatg tagcactaat
    14281 tcaaactgcg atacctgtgt tgcctttgtc tgattatcaa tgaatttcac ggcaaccttg
    14341 actttcacat tgtccccatc aaccgtaaag atagggttta ccaattcaga atagaggtag
    14401 tccctgccga tagactcaag cacatttcca gacacatagt aagcaagctc cttttctgtg
    14461 gctgttgggt atagcttaaa gaaagtttcc agaaatgcag tagcgtcatt tatggtatcc
    14521 gcgtctacac ttgcgtctgc ttctggtgtc tttggttcat agtctgattt ctcgattgct
    14581 ggtgcaaggg tagggttctg aataattacc atattcccgc cagcgtccac atgaactttt
    14641 acggtatagg ttgccttaac cgctgttgtc tgttccccct cttttatctg ctgatctact
    14701 tcgtaggtag cggaaaaagt gtccgttcca gactgttcaa tgctccatac aatcacatct
    14761 gtaatggcag agctggtcgg tatatccgtt ctaatggtat ccatattcaa gtcctgcaat
    14821 tcctttgtca gataaccgct gattgcctgc gtccttgcgt caatcgcttc tttgctgtta
    14881 ctccatgtgt aataggactt tgcaaaattc ttcacgaaat tttctatccc gttggtgtcc
    14941 tgcaagcgaa gctcaatcac ttctttttca tgggtcgtgt gctggtcaat agcggtaaaa
    15001 ttcttatata ctccaaagct cacgcttgca ataagcacca cccacaatgc aatcacggtt
    15061 ttcttatgtg tgcctacctt gacagtacgt accttttttt ctttgacatt ttctgtctgt
    15121 ttcttattct tcttaaacat atttttcaag tcctttctat tgttttactc gtcctgcacc
    15181 gattaagtgc tgttgccagt aactactact taggtctgta tatcctatcg ggt
//
LOCUS       DAEPKC010000096        15037 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.096, whole genome shotgun sequence.
ACCESSION   DAEPKC010000096 DAEPKC010000000
VERSION     DAEPKC010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15037)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15037)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15037
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.096"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            210..1133
                     /locus_tag="KR294_002996"
     CDS             210..1133
                     /locus_tag="KR294_002996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2520 domain-containing protein"
                     /protein_id="HBH0241056.1"
                     /translation="MGSGKVGTSLANYFLSKGYCVSGFYGRNQLSLLESTNLTKTKIY
                     SNLKDIIYENDILFITTSDDSIEIIDKKLSKFNLKHKYICHTSGSLKSSILFCSKKAG
                     ALIYSIHPIFAFSNKNTNIKKMKDICFSIEGDNEQDDLVIQNFIDDLGNQFFIRDKDT
                     SSTYHLANVLVSNLVLSLLDIGVSYFIKLGLSEEESLKAISPLVKKNIENILDNGFTK
                     ALTGPVSRGDITPIRKHLSVLDKKDEDIYKILSLNLLKIIALGNDNSLKGIKNITIEN
                     AIENLISKSEKYKEIYKLLGGKNDEKYHTDF"
     gene            1108..1935
                     /gene="panB"
                     /locus_tag="KR294_002997"
     CDS             1108..1935
                     /gene="panB"
                     /locus_tag="KR294_002997"
                     /EC_number="2.1.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011721175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate
                     hydroxymethyltransferase"
                     /protein_id="HBH0241057.1"
                     /translation="MKNTIQTFKNAKYEGKKLSMLTAYDYSIAKIMDECDINGILIGD
                     SLGMVIKGEENTLSVTIDEIIYHTKAVKNGVKNALIVSDMPFLSYHVSIEDAVKNAGR
                     LIKEGGAHAVKLEGGSNVIKQIESIVNAQIPVMGHLGLTPQSVNSFGGFKVQGNTSET
                     ARQLIEDAKLIEKAGAFSIVLEGVPTKIAEMVTNSISIPTIGIGAGINCDGQILVYQD
                     MLGMFGDFVPKFVKQYANIGDIMKDSIKNYILEVNTGTFPQEKHSFSINESELEKLY"
     gene            1954..2802
                     /locus_tag="KR294_002998"
     CDS             1954..2802
                     /locus_tag="KR294_002998"
                     /EC_number="6.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantoate--beta-alanine ligase"
                     /protein_id="HBH0241058.1"
                     /translation="MLVKEIKLLRNIIKDWRKHGYSIGLVTTMGFLHEGHQSLIKKAV
                     KENDKVVVSVFVNPTQFGPNEDFNSYPRDIDKDFKYCMDSGATVVFNPSPEEMYLKGN
                     CTTINVSGLTDFLCGAKRPVHFGGVCLVVSKFLNIVTPDKAYFGEKDAQQLAVIKRMV
                     KDLNIDTEIIGCPIIRENDGLAKSSRNTYLSEEERKSALILNKSLSLAKEELVKGNLN
                     PENIKELITAKINSEHLAKIDYVEIVDSETLQPVKQIEHSILVAIAVFIGKTRLIDNF
                     TFELNI"
     gene            3213..3395
                     /locus_tag="KR294_002999"
     CDS             3213..3395
                     /locus_tag="KR294_002999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241059.1"
                     /translation="MFKDKIDECVHIMTAYIASLKEYYSFIETQIGDFIKKYGEDVVE
                     LCLHRVMILLCECGLA"
     gene            4227..5141
                     /locus_tag="KR294_003000"
     CDS             4227..5141
                     /locus_tag="KR294_003000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2935 domain-containing protein"
                     /protein_id="HBH0241060.1"
                     /translation="MIDNQKYVILSLELHLFFSRIMKEHALFLEAGFTNKNYNLAMEA
                     DHYKKQFEDLLSYTVSASNGIIRPDILYSEELVTTLTSVAEQKTEEFTGIEINKNITT
                     RELNLQSGVNPQVGQDLVNYVAQLNSDAIRLLDGLINFKERVLDGVLSCTIFTSNYPL
                     LLEHIIHEANLYRYYVVDLENKIDIESKNAKEIELFWDHIMMEHALFMRGLLDPSEGE
                     LINTSNDFAIKFNELIEKTNEMTDSNIKNITEETLNETVEFKDFKEAGASGIEQCKIK
                     SIILPLLADHVLREANHYIRILESYKNM"
     gene            5531..6178
                     /locus_tag="KR294_003001"
     CDS             5531..6178
                     /locus_tag="KR294_003001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate utilization protein"
                     /protein_id="HBH0241061.1"
                     /translation="MIRQTPLEKRYDKLGPHIVTALKKRYFDAYYCKTRNEALQQILD
                     LIPQNHVVSWGGSETLKEMGVQTAVREKGFKVIDRDLAKTPEERTEIMRQALLCDTFL
                     MSSNAISEDGQLFNIDGNGNRVAAMIFGPKNVIVVAGMNKIVKNIDDAIQRTRTIASP
                     AVVQRFQDVNTPCYINGSCIDCTSPESICAYMVTTRISRPAKKIKVILVGENLGL"
     gene            complement(6345..6914)
                     /locus_tag="KR294_003002"
     CDS             complement(6345..6914)
                     /locus_tag="KR294_003002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBH0241062.1"
                     /translation="MKKFIICIIMFAISVLVLAGCTNDNKIKNEVDSMFNSIKTQDAD
                     TVDKYFPKSGLGNLIYEDKEGFKMYSKNMTWEISDIKNNKDKVTVDLKINNTDMVSIL
                     KKNPPKLGEMMPNPTMKDIDSAKKKEFNITLELVKSGDNYVCKVNQESAMKLLNVITG
                     GGIDYLADYNKDYYKQLDEEQKNYENKNS"
     gene            complement(6919..7818)
                     /locus_tag="KR294_003003"
     CDS             complement(6919..7818)
                     /locus_tag="KR294_003003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBH0241063.1"
                     /translation="MKLLSKVNNNIRLITQVAFTALTNGYVNGFLEGTIYGGESKKLC
                     VPGLNCYSCPGALGACPIGSLQAVLSSREYKFSFYVVGFLMAFGAFFGRFVCGWLCPF
                     GLVQDLLHKVPFPVKIKKVYGDKYLKYLKYIVLIMFVIILPVAIVNVAGGGNPWFCKW
                     ICPSGTLLGGILLILGNENLRESIGFLFSWKLSILLLILLMSIITYRPFCKYICPLGA
                     IYGFFNPISIYRFKIDKDKCTNCTACQTKCKLDIPIYKDVNSPDCIRCGECIKVCPQN
                     AITTTFSKDKKENNICAKKYRGI"
     gene            complement(7829..7978)
                     /locus_tag="KR294_003004"
     CDS             complement(7829..7978)
                     /locus_tag="KR294_003004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241064.1"
                     /translation="MSNFIKDNKKGISIIAISIIFIALGTYRGETNTVLTKAIMICLE
                     CIGIG"
     gene            complement(7971..8555)
                     /locus_tag="KR294_003005"
     CDS             complement(7971..8555)
                     /locus_tag="KR294_003005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HBH0241065.1"
                     /translation="MKRFFIVVLGCICVLGMISGCSKKESKPVEKNKNNSEWFSNLDT
                     EDVDGNKVTKEIFSNKELTLINVWTTWCGPCVGEMPELEALSKEYESNNSNVAIKGLV
                     VEVDKTDMRTGLSNEEKNLVKDIMKKSDATYQQLTVSEELKKTDFKRVMEFPTTYFVD
                     KKGNFVGEKVVGANSKEDWKKIIDERLKMVKANE"
     gene            8944..10269
                     /gene="cdeA"
                     /locus_tag="KR294_003006"
     CDS             8944..10269
                     /gene="cdeA"
                     /locus_tag="KR294_003006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MATE transporter CdeA"
                     /protein_id="HBH0241066.1"
                     /translation="MENLFTRKFTTFEFLKFVSPAIISMIFISLYTIIDGIFVSTLVG
                     SDALASINIVLPIINLVCGFGIMMATGGGAIVSIRMGENRQDEANSTFSFIVLFSLIV
                     GILFTVISYFFIKEISILLGATDKLLPYCITYGKVMILCTPFYILKFIFEYFARTDGN
                     SKFSLFLSVIGGVTNIILDYVFIKYFGMGLLGAAVATAIGIILTCVLGIIYFLSNKST
                     LKLGKPKTDFRLIRDTMINGSSEMVTELSTGITTFLFNVVALKLAGENGLAALTIVLY
                     AHFLMTSVYLGFAAGVSPLISYNFGAENSDKLKETFKHSLKFIFISSLLVFIIALVFA
                     PFIVRVFVNPDNTVFKLALQGLKIFAFAFLFVGINIFASGFFTAFHNGKISAIISFSR
                     AFVFIIIGIIILPPMLNMTGLWLTVPFAEVITIFISILFIKKYKCRYKY"
     gene            complement(10364..11158)
                     /locus_tag="KR294_003007"
     CDS             complement(10364..11158)
                     /locus_tag="KR294_003007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0241067.1"
                     /translation="MNELKPYIKFFNKNTKLYIIIFMIVGIVMNILPVFILKIFGEAS
                     KTNLSTIVNPILTYITILLFVYGVNIANKDFSGALSIRADRKSCIKAIVIDLIILSFV
                     ISILGIVLIFLSKLFIEIITGYSIELSVLLKRDMIWTSISALIDPSTSSMPLTYLNYF
                     VQICINEICIGFIGVLLGAFTYRVRKVTSITILIGLPILMVIYIVNFATKNMHKMLLY
                     LEKIIYSFQNPFILFGTKVGIIVICIIFIILLLRKAPIKEYANDLL"
     gene            complement(11159..12034)
                     /locus_tag="KR294_003008"
     CDS             complement(11159..12034)
                     /locus_tag="KR294_003008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0241068.1"
                     /translation="MSSSIKIENLSHSFKKQNIFNNMSLNFEKNKIYGLLGKNGAGKT
                     TLLNIMVNQLIQNEGEIEILGKNPKEDIKVLEEVCIVREKEFYSPDFKVGQIFEFSSS
                     FYKSYDKGLEKELCKYFDLNTKKKYKQLSRGMKTILSNIIGICSNSAITIFDEPTIGL
                     DAVNRQEFYNIILDSYIKNPRTIIISTHLIDEIDDLLEHVIILNEGKIIIDEEIDVIK
                     QKAHYITGNKEELEKLECIKNIKPKKAFGNAVAYFYYGDFSENDEKILKNSNIDVGYI
                     GLQDMFVNMTKKEEL"
     gene            complement(12038..12406)
                     /locus_tag="KR294_003009"
     CDS             complement(12038..12406)
                     /locus_tag="KR294_003009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH0241069.1"
                     /translation="MKLVLNNEEPIFIQIARAIEDEILSNGIKEEEQVPSTTELSKLY
                     KINPATVLKGINILVDKNILYKKRGIGMFVSDVAKTIIKEARKENFKHNFVKNLLQEA
                     NKLEINREELVDIIINFKED"
     gene            complement(12589..13248)
                     /gene="deoC"
                     /locus_tag="KR294_003010"
     CDS             complement(12589..13248)
                     /gene="deoC"
                     /locus_tag="KR294_003010"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HBH0241070.1"
                     /translation="MKHILKTVDHTILKATTTWEDIKILCDEAVDMSVASVCIPPSYV
                     KRASEYLKGKIKICTVIGFPLGYQTTATKVFEAKDAIENGADEVDMVVNISDIKNKDY
                     DNIGKEIKEIKKAIGDKVLKVIIETCYLDEDEKIKMCEIVTMSGSDFIKTSTGMGTGG
                     ATLEDIKLMKEHVGKNVKIKAAGGVKSISDAEKFIEAGAERLGTSSICKILKNEDTTD
                     Y"
     gene            complement(13284..14471)
                     /gene="murJ"
                     /locus_tag="KR294_003011"
     CDS             complement(13284..14471)
                     /gene="murJ"
                     /locus_tag="KR294_003011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein biosynthesis integral membrane protein
                     MurJ"
                     /protein_id="HBH0241071.1"
                     /translation="MKQEPCDFSHGRFRTGIIFIGITSVMSAFLQIKENFIVVGFGSI
                     PYNIVIIISIMLSTIFGPYILPIGAVVAMVVQLLFYMFFVKKTNYKYLYYLNFKDDSL
                     IKLLALLSPVFIGVAVNQVNSLVDTTLASTLVKGSIPALTYADRLNGFVTGTFTASIV
                     SVMYPMLSKLSAENNQKKFTSSVKSSINMIIISMIPISVASIFFATPVVRIIFERGAF
                     DARATQMTATALIFYAVGMTAFGLRDILGKVFYSLQDTKTPMVNGIISVGVNIVLDLV
                     LIKPMAHGGLALATSSSSIACILLLFLNLKRKVGYFGQDKIIKATLKSVVASLIMGVL
                     SYFTYKFIFGILGVGTFNEFVSLAISVIVGGGIYTLLMTIFKVEEVDMILNIAKRKLH
                     LKK"
     gene            complement(14548..>15037)
                     /locus_tag="KR294_003012"
     CDS             complement(14548..>15037)
                     /locus_tag="KR294_003012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBH0241072.1"
                     /translation="NKLAKLQRELSRKTIGSLNRNKARLKVARLQEHIANQRNDFLQK
                     LTTKLIKENDIICIEDLQVKNMIKNHKLSRLISDVSWSEFIRQLEYKANWHGRQIVKV
                     GKFFASSQICNKCGYKNEEVKNLNIREWICPSCNETHDRDINASRNILKEGLRLITIQ
                     NK"
BASE COUNT         5396 a         2192 c         1825 g         5624 t
ORIGIN      
        1 tactgatatt ttattatata aattttatag aattaattgt caatttttta tgaaaatggt
       61 aagatattta tggatggtat cttgttataa gaactatact ttaaatgttt ttaattattt
      121 tgtcttatgt aactcatatc ctcaggaatg agattagaaa ttaagatgtt gtatcacaaa
      181 gtggaggtga tactattaaa ataggcttta ttggttctgg aaaagttgga acatctttgg
      241 caaattattt tttatcaaaa ggttattgtg tttcaggctt ttatggaagg aatcaattat
      301 ctttattaga atcaacaaat ttaacaaaaa caaagattta cagcaatttg aaagatataa
      361 tttatgaaaa cgatatatta tttattacaa catcagatga ttctattgaa attatagaca
      421 aaaaactttc caaatttaat ttaaaacata aatacatttg ccacacaagt ggctctttaa
      481 aatctagtat attgttctgt tcaaaaaaag caggtgcatt aatttattct atccatccta
      541 tatttgcatt ttccaataaa aataccaaca taaaaaaaat gaaagacatt tgtttttcca
      601 tagaaggtga taatgaacaa gatgatttag ttattcaaaa tttcatagat gatttgggaa
      661 accaattttt tataagagat aaggatactt catccactta tcatttagct aatgttttag
      721 tttcaaattt agtattatct ttactagata taggagtaag ttactttatt aaattaggtt
      781 tatctgaaga ggaatcttta aaagctatca gtcctttagt aaaaaaaaat atagaaaata
      841 tacttgataa tggctttact aaagctctta ctggtcctgt ttctcgtgga gatataacac
      901 caataagaaa acatctatct gtattggata aaaaagatga ggatatttac aaaatactat
      961 ccttaaacct actaaaaata attgccttag gaaatgacaa ttcattaaaa ggtataaaaa
     1021 atattactat agaaaatgca atcgaaaatt taataagtaa atctgaaaaa tacaaagaaa
     1081 tttacaaact tttaggagga aaaaacgatg aaaaatacca tacagacttt taagaatgct
     1141 aaatatgaag gaaaaaaact atctatgctt actgcttatg actactcaat tgcaaaaata
     1201 atggatgagt gtgatataaa tggtatttta ataggagatt cattaggaat ggttataaaa
     1261 ggtgaagaaa acactctatc tgttaccata gatgaaatta tatatcatac aaaagctgta
     1321 aaaaatggtg taaaaaatgc cttaatcgta agtgatatgc cttttctatc ttaccatgtt
     1381 tctatagaag atgcagttaa aaacgcgggt agacttataa aagaaggagg agctcatgct
     1441 gtaaagttag aaggtggctc aaacgttata aagcaaatag aaagcattgt aaatgctcaa
     1501 atacctgtaa tggggcattt aggattaact cctcaatcag taaattcatt tggtgggttt
     1561 aaggttcaag gaaataccag tgaaacagca agacaactta ttgaagatgc taaattaata
     1621 gaaaaagcag gtgcattctc tattgtcctt gaaggagtgc ctacgaaaat agctgagatg
     1681 gtaactaatt ctatttcaat tcctacaata ggtatagggg caggaattaa ctgtgatgga
     1741 caaattttag tttatcaaga tatgttggga atgtttggag attttgttcc taagtttgta
     1801 aagcagtatg caaatatagg agatataatg aaagattcaa ttaaaaatta catcctagaa
     1861 gttaatacag gtacatttcc acaagaaaaa cacagctttt caataaatga atctgagtta
     1921 gaaaaattat actaatatta aggatggtac aaaatgcttg taaaagaaat taaattacta
     1981 agaaatataa tcaaagattg gagaaaacat ggctattcta tagggcttgt tacaacaatg
     2041 ggatttttac atgaaggaca ccaaagtctt ataaaaaaag ctgtaaaaga aaatgataaa
     2101 gtagtagtga gtgtatttgt aaatccaact caatttggac caaatgaaga ttttaatagc
     2161 tatccaagag atatagataa agattttaaa tattgtatgg atagtggagc aacagtagtc
     2221 tttaacccat caccagaaga aatgtattta aaaggtaatt gtactaccat taatgtttct
     2281 ggacttacag attttctttg tggagctaaa agacctgttc attttggagg tgtctgccta
     2341 gttgtttcaa agtttctaaa tatagtaaca cctgataaag cttattttgg agagaaggat
     2401 gcccaacaat tagctgtaat taaaagaatg gtcaaggatt taaacataga tacagaaata
     2461 ataggctgtc ctataattcg tgaaaatgat ggattagcaa aaagttcgag aaatacatat
     2521 ctctctgagg aagaacgaaa atctgctcta atattaaata agagcttaag tttagcaaaa
     2581 gaagaattag taaaaggcaa tctaaatcca gagaatataa aagaattaat aacagctaaa
     2641 ataaattctg aacacttagc aaaaatagac tatgttgaaa ttgtagatag tgagacatta
     2701 caacctgtta agcaaataga acattctata cttgtggcaa ttgctgtgtt tataggaaaa
     2761 accagactaa ttgataattt tacatttgag ttaaatatat agtctataat tttatataat
     2821 atatctaaaa aataatagaa tacctaaaaa gtaataaatt acctaaaaaa taataaattg
     2881 cttagaaaat aatagattac aataactaaa attttaaaat taaattcctt aaaagtatga
     2941 ttaattataa ttatataagt atattcttat tacacttata ttaatttata ttaaatatct
     3001 actaactcaa atattcataa ttaaacttta aactggataa attttctttt aagaatgaaa
     3061 gtttatccag ttttgcgatt ataataacca gttttacata tccacttgta aaatatatct
     3121 aagcaatata tcatactata tagatttatg agtgaaataa tatctgctat ttactgaata
     3181 tttttatttt tcgtttttta gggggattag ttgtgtttaa agataagatt gatgaatgtg
     3241 ttcatataat gactgcatat attgctagtt taaaagaata ctattcattc atagaaactc
     3301 aaattggtga ttttattaaa aaatatggag aagatgttgt agagttatgt ctccatagag
     3361 tgatgattct actatgcgaa tgtggtttgg cataaaatta aatttattaa aatgggtaag
     3421 aagaatccta tataatattc ttcttaccca ttttaatata tcaatttcat agcttatcgt
     3481 ttaaaatatt ttacatccat tactagacaa ctttacattc tctttttaat tctagtatat
     3541 ttaaatcatt ttagttgctc cttatttatt cttattactt gttttatttt ataaataaaa
     3601 taattctttt taataatgtt ttttgttgat attcctatca cacatccaat tatttatcat
     3661 tgtcttgaaa ttgtttgcat acttaattta atccaattga aacaccccag catagaatcc
     3721 cctgtaaaat agaagttgga ttaaatccta acatctatac agaaaatact actccaagca
     3781 caagcaatat aatggaatat atttatcact taatttttta tactttttaa atcccatacc
     3841 taaagcatta agtgcagcta ttagaattaa taattgttgt ggtataaaat tatgcttgct
     3901 tcatatttat tcatttttta ctataaaagt tcttgtttta caaaaaacat ttgttttgta
     3961 tcaaaataat acttgtaaat tacataattc tcataaaaat ttctagtatt acttgtactc
     4021 ttaataaata atagccaaca agtaccttaa atcattatat ctatatctaa taagaaacac
     4081 agtaagataa ttttttcgcc cataacttaa taaaaactgt tgatattagt agcaattgaa
     4141 tttagttaat ttatttataa tatacataaa tttaaatatt acgaataaag tattataaat
     4201 aggatacttt ctaaagggag gaaattatga tagataatca aaaatatgtt attttatcac
     4261 tagaattaca tttatttttt tcaagaatta tgaaagagca tgctcttttt ttagaagcag
     4321 gattcacaaa taaaaattat aatcttgcta tggaagctga ccactataaa aagcaatttg
     4381 aagatttatt atcatacact gttagtgcta gtaatggtat aattagacct gatatattat
     4441 attcagaaga gcttgtaact actctcacat cagttgcaga acaaaaaaca gaagagttta
     4501 cagggataga aataaacaaa aacatcacta caagagaatt aaatctacaa agtggtgtaa
     4561 acccacaagt tggtcaagac ttagtgaact atgtagctca acttaactct gatgcaataa
     4621 gattacttga tgggcttatt aattttaaag aaagagtctt agatggtgta ctatcatgta
     4681 ctatatttac atcaaactac cctctacttc ttgaacatat aatacatgaa gcaaatttat
     4741 atcgttatta tgtagttgac cttgaaaata aaatagatat tgagtcaaaa aacgctaaag
     4801 aaatagaatt attctgggac catattatga tggaacatgc tctgtttatg agaggattac
     4861 tagacccctc agaaggtgaa ctaataaata cttcaaatga ttttgctata aaatttaatg
     4921 aattaattga aaaaacaaac gaaatgactg attctaatat caagaacatt acagaagaaa
     4981 ctctaaatga aactgttgag tttaaagatt ttaaagaagc aggagcatca ggaatagaac
     5041 agtgtaagat aaaatctata atattaccac ttttagcaga ccatgtttta agagaggcaa
     5101 atcattatat tagaatattg gagagttata aaaacatgta attaaaaatt acttttaaaa
     5161 taatctttgc atatttagat aaaataaagg tacagttaac tgtaccttta ttttttataa
     5221 acttataaaa tttaaacaag ttattcataa aataaaataa taatcatcta taacccacaa
     5281 ctttatttta tattaaataa aaagtattag tgattatgtt ttataggtat ttctttattc
     5341 agttatttat taaaaactaa tagtaaatct tatactaatc gcatatttat gttataacta
     5401 tattgtaact attttcgtaa tcttaggaaa agattactta taaaattaac cttatacaat
     5461 aatatatcgt ataatcttaa ttagcataat agttacaata ttaaaattta aatatgggag
     5521 tgattttagt atgataagac aaacaccatt agagaaacga tatgacaagc taggtcctca
     5581 tattgtaaca gcactcaaaa aacgttattt tgatgcttat tactgtaaaa ctagaaatga
     5641 agctttgcaa caaattttag atttaattcc tcaaaatcat gtagtatcat ggggaggatc
     5701 tgaaacactt aaagaaatgg gcgtacaaac tgctgttaga gagaaaggat ttaaagttat
     5761 tgatagagat ttagcaaaaa ctccagaaga aagaactgaa attatgcgtc aagcacttct
     5821 atgcgatact tttttgatga gtagcaatgc aattagtgaa gatggacaac tctttaatat
     5881 tgatggaaat ggcaatcgtg tagctgcaat gatatttggt ccaaaaaatg ttatagttgt
     5941 agctggtatg aataaaattg taaaaaacat tgatgatgca atacaaagaa ctagaacaat
     6001 tgcatctcca gcagttgttc agcgttttca agatgtcaat acaccatgct atattaatgg
     6061 aagttgtata gattgcacaa gccctgaaag catttgtgca tacatggtta ctacaagaat
     6121 cagtcgtcca gcaaaaaaaa taaaggtaat attggtagga gaaaatcttg gtctataaaa
     6181 tatacataca tgtaaatagc tctataaata ataaaatcat atgaaataac ttatttctaa
     6241 aagtggtaga ataaaagctt ctacaagact ttcattctac cacttttata ttcttttaat
     6301 ttgtgtttct atattattaa ttgctccgat tttcatatat attactaact atttttattt
     6361 tcataatttt tttgttcttc atcaagctgt ttataataat ctttattata gtcagctaga
     6421 taatctatac cacctcctgt aatcacattt aataatttca ttgcagattc ttgattaact
     6481 ttacaaacat aattatcacc agatttaaca agctctaatg taatattaaa ttcttttttc
     6541 tttgcagaat caatatcttt catagttgga tttggcatca tttctcctag tttaggagga
     6601 ttctttttta aaatagaaac catatcagta ttgttaattt ttaaatctac agtcacttta
     6661 tccttattat tctttatatc tgaaatttcc caagtcatat ttttagaata cattttaaat
     6721 ccttctttat cttcgtatat aagattacct aaccctgatt ttgggaaata cttatcaaca
     6781 gtatctgcat cttgtgtttt tattgaatta aacatactat ccacttcatt ttttatctta
     6841 ttatcattag tacaaccagc taacaccagt actgatattg caaacattat aatacatata
     6901 ataaatttct tcattaaatt atatccccct atactttttt gcacaaatat tattctcttt
     6961 tttatctttt gaaaaagttg tagtaattgc attttgtgga caaactttta tacattcacc
     7021 acacctaata cagtctggac tatttacatc tttatatatt ggtatatcaa gcttacattt
     7081 tgtttgacat gctgtacaat ttgtacattt atctttatca attttaaatc tatatattga
     7141 aataggatta aaaaaaccat agattgctcc taaagggcat atatacttgc aaaatggcct
     7201 ataagtaatg attgacatca ataatatcaa tagcaaaata cttaacttcc agctaaataa
     7261 aaatcctatt gattctctta aattctcatt tcctaaaata agtagtattc ctcccaaaag
     7321 tgttcctgaa gggcaaatcc atttacaaaa ccaaggattt ccaccccctg ctacatttac
     7381 aatagcaact ggcaaaataa ttacaaacat tattaagact atatacttta gatattttag
     7441 atatttatca ccataaactt tttttatctt tactggaaag ggtactttat gtagtaaatc
     7501 ttgtacaagt ccaaagggac aaagccaacc acaaacaaat ctgccaaaaa aagcaccaaa
     7561 tgccattaaa aaaccaacaa cataaaatga gaatttatac tctctgcttg ataaaactgc
     7621 ttgtaatgaa cctattggac atgctccaag tgcacctgga catgaataac aattcaatcc
     7681 aggtacacat aattttttac tttctcctcc atatatagtt ccttctaaaa atccatttac
     7741 atatccattt gttaatgctg taaatgcaac ttgagtaata agtcttatat tattatttac
     7801 cttagataat aacttcatcc ctcttctcct aaccaatacc aatacactca agacaaatca
     7861 taattgcttt agttaatact gtatttgttt ctccacgata tgtacctaat gcaataaata
     7921 taatactaat tgcaataata gaaatgcctt ttttattatc tttaataaag ttactcattg
     7981 gcttttacca tttttagtct ttcatctata atttttttcc aatcttcctt actatttgca
     8041 cctacaacct tctcacccac aaagtttcct ttcttgtcta caaaataagt tgttggaaac
     8101 tccataactc ttttaaaatc agttttttta agttcttcag atacagtcaa ttgttggtaa
     8161 gttgcatctg actttttcat aatgtcttta actaaatttt tctcttcatt tgaaagacca
     8221 gttctcatat cagttttatc aacttctaca actaatccct ttatagctac attggaatta
     8281 ttactctcat attcttttga taatgcttca agctctggca tttcacccac acatggtcca
     8341 caccaagtag tccagacatt aataagagta agttctttat ttgaaaatat ctcttttgtt
     8401 accttatttc catcaacatc ctccgtatct aaattactaa accattcact attattcttg
     8461 tttttttcta ctggcttaga ttcttttttg ctacatccag aaatcatacc taaaacacaa
     8521 atacatccta aaactactat gaaaaacctt ttcatatctc acactcctag aatttatata
     8581 gtatataaaa tcgctgcttg aaataaaaat aacttatctt ctatattaaa gtaattatat
     8641 ttaataaata agagctaatt taaaaaaaga tatacagtta aaatctattt cttttcagac
     8701 aaaatcttat atatatataa tagcttgtaa atcttaagat tatatacata tatttctaaa
     8761 gattttctta agaaacagtt agattttact aatataagtt tattaattag cattatacta
     8821 atttatctta atatgatttt ttgttgattt taagctgttt atcgtataaa taaaattttt
     8881 cttgactata tagttactat atagcttatt atatatagag agtaataaaa ggaggtaaaa
     8941 tttatggaaa atttatttac aagaaaattc actacttttg aatttctaaa atttgtttct
     9001 cctgcaatta tatccatgat atttatatct ttgtatacaa taatagatgg catctttgta
     9061 tcgacattag ttggttctga tgctcttgct agtataaata ttgtactacc tataattaac
     9121 cttgtttgtg gatttggaat aatgatggca actggtggag gtgctatcgt ttctatacgt
     9181 atgggtgaaa atagacagga tgaagccaac tctacatttt cttttatagt tttgttttca
     9241 ttgattgttg ggattttatt cacagtaatc tcatatttct ttatcaaaga aatatctatt
     9301 ttgcttggtg caacagataa gttattacca tattgtataa cttatggtaa agttatgatt
     9361 ttatgtacac cattttatat tttaaaattt atatttgagt actttgcaag aactgatgga
     9421 aattctaaat ttagtttatt tctatcagtc attggtggtg taacaaatat aatattggat
     9481 tatgtattta ttaaatattt tggaatgggt cttttaggag ctgcagttgc aactgctata
     9541 ggtattattt taacttgtgt tttaggtatt atttacttct tatctaataa atctacacta
     9601 aaattaggaa aaccaaaaac cgattttaga cttataagag atactatgat aaacggttct
     9661 tctgaaatgg ttacagaatt atctacagga attacaacat tcttatttaa tgtagtagct
     9721 ttaaaattag caggagaaaa tggacttgct gctcttacta tagtattgta tgctcatttt
     9781 ttaatgacat cagtctatct aggattcgct gctggagtgt ctccattaat aagctataat
     9841 tttggtgctg aaaacagtga taaattaaaa gaaacattta aacattctct aaaatttata
     9901 tttatttctt ctcttttagt gtttattatt gctttagtat ttgcaccatt tattgttagg
     9961 gtctttgtaa atccagataa cacagtattt aaactagcct tacaaggatt aaaaatattt
    10021 gcatttgctt ttttgtttgt tggtataaat atatttgcat caggattttt tacagcattt
    10081 cacaatggaa aaatttcagc tattatatct tttagtcgtg cctttgtttt tataatcata
    10141 ggaatcataa ttcttcctcc tatgttaaac atgactggat tatggcttac agttccattt
    10201 gctgaggtta taaccatatt tatatctatt ctatttataa aaaaatataa atgtagatat
    10261 aagtattaaa aattaatact taaaatcaac atttattaaa actaataaac ctgctttaaa
    10321 atacaaattt acaaatttga tttttaagca ggttttattt tagttataat aagtcatttg
    10381 catactcttt aattggtgct tttctaagta ataaaattat aaatattatg caaataacta
    10441 taattcctac ctttgttcca aataaaataa aaggattctg aaatgaataa ataatttttt
    10501 ctaaatacaa tagcatttta tgcatatttt tagttgcaaa attaactata taaattacca
    10561 ttaatatcgg taatcctatc aatatagtaa tactagtaac ttttctaact ctatatgtaa
    10621 aagctccaag taacactcct ataaaaccta tacatatttc atttatacat atttgtacaa
    10681 aataatttaa ataagttagt ggcatacttg atgttgaagg atctatcagt gctgatatag
    10741 atgtccaaat catatctctc tttagtaaaa ctgatagttc tatactgtaa cctgttataa
    10801 tttctataaa taacttcgat aaaaaaatca aaactatacc taaaatagaa atcacaaagc
    10861 ttaaaataat taaatctatg acaatagctt ttatacaact ttttctatct gctcttatac
    10921 ttaaagctcc tgaaaagtct ttatttgcta tatttactcc atacacaaat agcagtatag
    10981 ttatatatgt taaaatagga ttcacaatcg tggataaatt agttttagat gcttctccaa
    11041 aaatcttgag aataaacact ggcaaaatat tcataacaat tcccacaatc ataaatataa
    11101 ttatatacaa tttagtattt ttattaaaaa attttatata tggctttaat tcattcaatt
    11161 acaattcctc cttcttagtc atgttaacaa acatatcttg tagccctatg tatcctacat
    11221 caatatttga atttttaagt attttttcat cattttcact aaaatcacca tagtaaaaat
    11281 aagcaactgc atttccaaat gcctttttag gttttatatt ttttatacat tctaattttt
    11341 ctaactcttc tttatttcca gtaatataat gagctttttg ttttatgaca tcaatttctt
    11401 catctataat aatttttccc tcatttaata ttattacatg ctccagtaaa tcatctattt
    11461 catcaatcaa atgagttgat attattattg tccttggatt ttttatataa ctatctaaaa
    11521 ttatgttata aaactcttgt ctatttactg catccaaacc aattgttggc tcatcaaata
    11581 tggtgatagc tgaattagaa caaataccta ttatatttga aagtatagtt ttcatacctc
    11641 ttgacagttg tttatacttt tttttagtat ttaaatcaaa atatttgcat aattcttttt
    11701 ctaagccttt atcataactt ttataaaaac tagaagaaaa ttcaaatatc tgacctactt
    11761 taaaatctgg actataaaat tctttttccc tgacaataca aacttcttcc aaaactttta
    11821 tatcttcttt tgggttcttt cctaatattt ctatctcacc ttcattttga attaactgat
    11881 ttaccattat atttaataat gttgtttttc cagctccatt cttacctaat aaaccatata
    11941 tcttattttt ttcaaagttt agagacatat tattaaaaat attttgcttc ttaaaactgt
    12001 gagataaatt ttctatctta atagaactac tcatatatta atcctccttg aaattaatta
    12061 taatatcaac caattcttct ctatttattt ctaatttgtt agcttcttga agtaggtttt
    12121 ttacaaaatt atgtttaaaa ttttcttttc tagcttcttt tataatagtt tttgcaacat
    12181 ctgatacaaa catccctatc cccctcttct tatataaaat atttttatca accaatatat
    12241 ttataccttt taatactgta gctggattaa ttttataaag ctttgaaagc tctgttgttg
    12301 atggaacctg ttcttcttct tttattccat ttgatagtat ctcatcttca attgctcgtg
    12361 ctatctgaat aaatataggt tcttcattat ttaatactaa tttcataggt tcctcctttc
    12421 tccattagtt agttactcaa ctaattaact atataactta taatatcttg aaaaatattt
    12481 tctgtcaata ctaaataaaa aacagaggga aaattccctc tgttttttgt tctttatatt
    12541 tataattaaa ttttgatttt tgtaatccta tcccataagt taaaaacttt aataatctgt
    12601 tgtatcttca ttttttaata ttttacatat tgagctagtt cctaaccttt ctgctcctgc
    12661 ctctataaat ttttctgcat cagaaattga tttaactccc cctgcagctt ttatttttac
    12721 attttttcca acatgctctt tcataagctt tatatcttct aaagtagctc cacctgttcc
    12781 cattccagta gatgttttta taaaatctga acctgacatt gttactattt cacacatttt
    12841 tattttttca tcttcatcta aataacatgt ctctataatg acttttaata ctttatctcc
    12901 tatagctttt tttatttctt ttatttcttt tcctatatta tcataatctt tattttttat
    12961 atctgaaatg tttacaacca tatcaacttc atctgctcca ttttcaatag catcttttgc
    13021 ttcaaatact tttgtagcag tagtttgata tcccaaaggg aaccctatca ctgtacatat
    13081 ctttatttta ccttttagat attctgatgc tcttttcaca tatgatggtg gtatgcaaac
    13141 tgatgctaca ctcatatcta cagcttcatc acataaaatt ttaatatctt cccatgtagt
    13201 tgtagctttt aaaatagtat ggtctactgt ttttaatata tgtttcataa aatcctccta
    13261 aatttataat taatataatt agattacttt tttaaatgca attttctctt tgcaatattc
    13321 agtatcatat caacctcttc aactttaaaa atagtcatta gtagtgtata aattccacct
    13381 ccaactataa ctgaaatagc tagtgagaca aactcattaa atgttcctac tcccaaaatt
    13441 ccaaatataa atttatacgt aaagtatgat aaaacaccca taattaaaga tgcaactacc
    13501 gatttcaaag ttgcttttat tattttatct tgtccaaaat atccaacttt tctctttagg
    13561 ttcaagaaga gtaacaatat acatgcaatt gatgatgaac tagttgcaag agcaagacca
    13621 ccatgagcca ttggttttat taaaactaag tccaatacta tatttacccc tacagatata
    13681 atcccattta ccataggtgt ttttgtgtct tgtaatgaat aaaaaacctt tcccaaaata
    13741 tctcttaagc caaatgcagt cataccaact gcataaaaaa ttaaggcagt tgctgtcatt
    13801 tgggttgccc tcgcatcaaa agcacctctc tcaaaaatga ttctaacaac aggagttgca
    13861 aaaaaaatag aagcaactga aataggaatc atagaaatta ttatcatatt tatactagat
    13921 ttaactgaac tagtaaactt cttttgatta ttttctgcac ttaacttaga taacatagga
    13981 tacataacag atactattga agctgtaaat gtccctgtaa caaaaccatt taatctatct
    14041 gcataagtaa gtgctggaat gcttccttta actaatgttg aggctaaagt tgtatctacc
    14101 aatgagttca cttgattaac agcaacacct ataaatactg gtgaaagtaa tgctagtaat
    14161 ttaataaggc tatcatcttt aaagtttaag tagtataagt atttgtagtt cgttttttta
    14221 acaaaaaaca tgtaaaagag cagttgaact accatagcaa ccacagcacc aattggaagt
    14281 atgtatggtc caaatatggt acttaacatt attgaaataa ttattactat attatagggt
    14341 atacttccaa atccaactac aataaagttc tctttaattt gtaaaaatgc tgacataaca
    14401 cttgtaatac ctatgaatat tattcctgtt ctgaacctcc catgactaaa gtcacagggt
    14461 tcctgcttca tagaattttg catactaaaa tatgtcttac taattctcca caggctatcc
    14521 ccgtagttcc tacggttctt acatacgtta tttattttga attgttatta gtcttaatcc
    14581 ttcttttaat atatttctac ttgcatttat atctctatcg tgagtttcat tacaactagg
    14641 acaaatccat tctcttatat ttaagttctt aacttcctcg tttttatacc cacatttatt
    14701 gcatatttgt gaacttgcaa agaatttacc tacctttaca atttgtctac catgccaatt
    14761 agccttgtat tctaattgac gaataaactc tgaccatgat acatcagaaa ttaagcgaga
    14821 tagtttatga tttttaatca tattctttac ttgtaaatct tctatgcaaa taatatcatt
    14881 ctcttttatt aatttagtag ttaatttttg tagaaaatca tttctttgat tagctatatg
    14941 ttcttgaagt cttgcaactt ttaatcttgc tttatttcta tttaaactac cgattgtttt
    15001 tctcgataat tctctttgta atttagcaag tttgttt
//
LOCUS       DAEPKC010000097        14776 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.097, whole genome shotgun sequence.
ACCESSION   DAEPKC010000097 DAEPKC010000000
VERSION     DAEPKC010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14776)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14776)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14776
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.097"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(368..829)
                     /locus_tag="KR294_003013"
     CDS             complement(368..829)
                     /locus_tag="KR294_003013"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HBH0241073.1"
                     /translation="MIYEGKLIGKDLKIGIINSRFNEFITSKLLSGAEDCLLRHDVSP
                     ENIEIVWVPGAFEIPLVAQKMAKSGKYDAIICLGCVIRGATSHYDYVCSEVSKGIAKV
                     SLDSELPVIFGIVTTENIEQAIERAGTKAGNKGYDCAMNALEMANLFKSLD"
     gene            complement(934..2127)
                     /locus_tag="KR294_003014"
     CDS             complement(934..2127)
                     /locus_tag="KR294_003014"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HBH0241074.1"
                     /translation="MFNTIEEAIEDIKNGKMVIVVDDESRENEGDLLMAAEMATPESI
                     NFMATYGRGLICLPATEKKFKSLNIPLMVRENTDTFQTAFTVTIDGADTLTGISAYER
                     AETVKLFCDENSTSKDFKTPGHIFPLIAKTGGVLVRDGHTEASVDLARLAGFKEIGLI
                     CEIMKDDGTMARVDDLMIFKEKHNLKIITIKDLIEYRKINETTIEKVSSAFLPTKYGN
                     FEIIGYRDTYSNEEHIALTYGNINIENTLVRLHSECLTGDVFHSLKCDCGLQLESSMK
                     KIVENGSGVLIYMKQEGRGIGLLNKIKAYKLQEEGYDTVEANLMLGFEEDMRDFYMAA
                     QILKNLNIKSINLLSNNPDKINQLEKYGIKIENRIPINEEINDFNKLYLKTKKDKMGH
                     LLDII"
     gene            complement(2150..2815)
                     /locus_tag="KR294_003015"
     CDS             complement(2150..2815)
                     /locus_tag="KR294_003015"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HBH0241075.1"
                     /translation="MFTGIVEEVGILRKITANGKSGKVTILSNKILDGTNLGDSIAVN
                     GVCLTVSNLGKNEFTADVMMETIRSTNLGLLNANDKVNLERAMSLSSRFGGHIVTGHV
                     DGKGTICKFEKDENAVLVSIRPDKKLLSSMILKGSVAIDGVSLTISYLDDEIFKVSII
                     PHTKINTILLTKNVGDFVNLESDVIGKYVNNFMANNYKELNSNSSNHKSNIDKDFLFK
                     NGF"
     gene            complement(2849..3961)
                     /gene="ribD"
                     /locus_tag="KR294_003016"
     CDS             complement(2849..3961)
                     /gene="ribD"
                     /locus_tag="KR294_003016"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HBH0241076.1"
                     /translation="MNFVNQKEKDIYYMKKAIELAKNGEGFVNPNPLVGCVIVKDSNI
                     IGKGYHEKFGSNHAEVNAINSAKQSLKDSTLYVNLEPCSHYGKTPPCVDKIIQNKIKR
                     VVISTLDPNPLVCGNGVKKLKDNNIDVTVGILEDEARDLNEAFFYHIKNKRPLCIVKS
                     AVSLDGKIATKSLESKWISNESSRYLTHKYRNKYQSIMVGINTVLNDNPLLTCRLNQE
                     KVSHPTRIVIDTHLKLPLNSNLVKDKTSKTIVFTCCKESIKLSMLKENNVETIISPSK
                     NNLVDLEFVMYKLGELNIDSVLVEGGATLNDSLFRNKLVDKVKLFLSPKIIGGKDAPT
                     FVSGEGINHLSDSTQLTINNVTLIDGDILIESDVLN"
     regulatory      complement(4093..4214)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            4403..6885
                     /gene="recQ"
                     /locus_tag="KR294_003017"
                     /pseudo
     CDS             4403..6885
                     /gene="recQ"
                     /locus_tag="KR294_003017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729557.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
     regulatory      6974..7085
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            7227..8528
                     /gene="thiC"
                     /locus_tag="KR294_003018"
     CDS             7227..8528
                     /gene="thiC"
                     /locus_tag="KR294_003018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomethylpyrimidine synthase ThiC"
                     /protein_id="HBH0241077.1"
                     /translation="MNYTTQMDAARKGIITKEMEIVSQKEQVDVNELRELIANGQVVI
                     PANKNHKSLSAEGVGKNLRTKINVNLGISRDCKDIEKELEKVRVAIDMKAEAIMDLSN
                     YGKTREFREKVVEMSPAMIGSVPMYDAVGYLEKELKDITEEEFLNVIRQHAIDGVDFI
                     TIHAGLTRSVCQKIKNHERLTHIVSRGGSLLFAWMELNNKENPIYTNFDKILDICEEY
                     DVTLSLGDACRPGCIKDSTDGVQIQELVVLGELTKRAWERNVQVMIEGPGHMAIDEIE
                     ANVVLEKRLCHGAPFYVLGPLVTDIAPGYDHITSAIGGALACAKGVDFLCYVTPAEHL
                     RLPNLDDMKEGIIAAKIAAHAGDIAKNVKGAREWDNKMSKARADLDWCEMFRLAIDPE
                     KAKRYRDESTPTHEDSCTMCGKMCSMRTVKKILNNEELNLI"
     gene            8582..8776
                     /gene="thiS"
                     /locus_tag="KR294_003019"
     CDS             8582..8776
                     /gene="thiS"
                     /locus_tag="KR294_003019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfur carrier protein ThiS"
                     /protein_id="HBH0241078.1"
                     /translation="MKVNGKEIEFEKDLTVIDLLNKYNLKSDRVVVEVNLEIIEESNY
                     NTYVLKDEDIVELISFIGGG"
     gene            8769..9572
                     /gene="thiF"
                     /locus_tag="KR294_003020"
     CDS             8769..9572
                     /gene="thiF"
                     /locus_tag="KR294_003020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine biosynthesis protein ThiF"
                     /protein_id="HBH0241079.1"
                     /translation="MVKIKIFVNELLTDVEENTTAYKVRDSYNNKCDVLVLNGYPIKT
                     DMTLCENDKLTLIQKGVKPSLDELESLLIARHTPNIHNKLKKGKVAILGLGGLGSNIA
                     ISLARIGVGELLLIDYDVVEPSNLNRQQYFIDDIGKLKTDAMIENIKKINPFIKLNKR
                     DIFLNKNNMDTIKDSDLIIEAFDDASCKAQVCNYVLINLKDKYLIASSGMAGYYDSNI
                     ITTKKIKDRFYICGDFVNEAKFGEGLMAPRVAICANHMANLATQILIDM"
     gene            9635..10405
                     /locus_tag="KR294_003021"
     CDS             9635..10405
                     /locus_tag="KR294_003021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018592874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiazole synthase"
                     /protein_id="HBH0241080.1"
                     /translation="MDKLVLGGHEFNSRLLVGTGKYGSNNILPEVIKESGSEIITMAL
                     RRVDLDNKQENILTYIPKEMTILPNTSGATNAEEAVRIARISRKMGCGDFIKIEVISD
                     TRYLLPDNEETIKATKILADEGFIVLPYMTPDLYAGRRLIEANAAAVMPLGAPIGSNR
                     GLQMKEMIRIMIDELDIPIIVDAGIGKPSQAMEAMEMGADAVLVNTAIASAGDPVQMA
                     RAFKLAVEGGREAYIAKTGNVSEFANASSPLTGFLGNL"
     gene            10422..11525
                     /gene="thiH"
                     /locus_tag="KR294_003022"
     CDS             10422..11525
                     /gene="thiH"
                     /locus_tag="KR294_003022"
                     /EC_number="4.1.99.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-iminoacetate synthase ThiH"
                     /protein_id="HBH0241081.1"
                     /translation="MSFYDVIEKYRDFDFDGYLNNVTDNDVLRSLSKDKLEDFDILNL
                     LSKTAVKHLEDMAQKAHKLSVQYFGKTVCLYTPMYIANYCVNQCVYCSYNIKSGIKRK
                     KLTMDEIREEGEAISKEGFKHLLVLTGESSFHSSVEYIGEAIEILREKFPSIGIEVYP
                     MEVEEYKYIVDKGVEGLTVYQETYDEEIYKRVHIKGPKSNYKFRLDAPERGAKAGMRT
                     LSIGALLGLNDFRKETFFTILHGKYLKTKYPHIELSYSTPRMRPFKGCFEELVDISDT
                     DLVQAMVCMRLFDPHAAINISTRENLEMRSHIIPLGVTKLSAGVSTDVGGHSQDEHDT
                     AQFKINDESTVKDVEKMLNSIGYQHVFKDWERF"
     gene            11526..12215
                     /locus_tag="KR294_003023"
     CDS             11526..12215
                     /locus_tag="KR294_003023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HBH0241082.1"
                     /translation="MYLITNRKLCSEERYLEVIKESILSGVENIIIREKDLEYQELRK
                     LYMKIKTKINCIDFQEQISDESLKTNINQKECRNKFKVNFIINSNIEFFEKVDCQGIH
                     LPFKLFLNLIENKYNFNENKILGLSLHKVEEVDYLEKLIRNQNIKIDYITLSHIYETK
                     CKEGLNPKGIELLKEAKKITDIKIIALGGILPSNVKETLKYCDDFAIMSTIMRSKDIK
                     KTISNYNEKLN"
     gene            12403..13797
                     /gene="yfcC"
                     /locus_tag="KR294_003024"
     CDS             12403..13797
                     /gene="yfcC"
                     /locus_tag="KR294_003024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HBH0241083.1"
                     /translation="MTDSKKKRFIIPHTFTIIFLLIVLMAILTWIVPSGEFSREDVEG
                     RMVVVPGTYQSVESNPQGFADVFKAPIEGFIDSAEVVGFVLIVGGAFGIVNRTGAIEA
                     GIASVISKFKGKELLIIPISMILFGLGGTTFGMAEETLPFYMIFVPLMTSLGYDSLTA
                     IAIVFIGAAAGAAASTINPFSVGIAQALAQLAPGSGVTYRVVIFIAYILISIAFVMYY
                     AKKVKENPESSIVYEIDKNNKSILNQTSTEIKEFTFKEVSVLAIFGIGMAIMIWGVLS
                     QGWYIPEISMCFAAIGVLSGLVGRLSQIEISESFIDGAKDLASAALAIALARGIVIIA
                     QNGFIIDTILNSAAAFLGGLPKVIFVYLSFFLEAALAFLIPSSSGLASLTVPVLAPLG
                     DLVNISAQVIVTAYQFGVGLTNFITPTSGVLMGALAVAHIPFSKWVRFIMPILLILTA
                     VSLVFLTIGIYIGF"
     gene            14314..>14776
                     /locus_tag="KR294_003025"
     CDS             14314..>14776
                     /locus_tag="KR294_003025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase"
                     /protein_id="HBH0241084.1"
                     /translation="MGLKEFDFIEESIDMLRTMSPTLETISDEIEEYFENILDEKNQE
                     YINVTSRIKSESSLREKIIRNRYLKKYGEASNLIHNVSDLIGLRIECRFIEDENKIYR
                     LLRRYFNKTDDKINYYNKENKNIKLKLSERQPNKQKNGFEIYKIDGVFAYLD"
BASE COUNT         5598 a         1745 c         2433 g         5000 t
ORIGIN      
        1 taaattatag tgttttatta ttaattgttc ttaattatat tgtatggtaa attaaaaaag
       61 taataaaata gataattaat atactagtaa tatatgctat aaataaaaac aatagctaaa
      121 atagtaatat atatgttttt atgatatttt atgtttaggg ttatatttgt aattatttta
      181 agcttctaaa agtagatttg atggataacg tataatttta gaaggatatg caatttgttt
      241 gataagaacg tacatatgat taaattaaaa atattaagta ccaaaaagaa gaaagatagt
      301 ttctcccttt ggtacttaat attttgtatc ctttacacta atttttaata tttattaatg
      361 atattattta atctagagac ttaaataaat ttgccatttc tagcgcattc atagcacaat
      421 cataaccttt atttccagct tttgtacctg ctctttcaat agcttgttca atattttctg
      481 tagttacgat tccaaatata acaggtaatt cactgtctaa agatactttg gctatccctt
      541 tagagacttc actacataca taatcataat gagaagtagc ccctcttata acacagccta
      601 aacagattat agcatcatac ttaccacttt tagccatttt ttgagcaaca agaggaatct
      661 caaaagctcc aggtacccaa actatttcta tattttctgg agaaacgtca tgtcttaaaa
      721 gacagtcttc agctcctgat aaaagttttg atgttataaa ttcattaaaa cgagaattta
      781 ttatacctat ttttaaatct tttccaataa gttttccttc atatatcatt tttacttcct
      841 ccaattttat ttatgttata gatttatatt tataaatatc tttaatttaa ttataaaaaa
      901 ctacttagta gaaaaatatc atcatataat catttatata atatctaaaa gatgtcccat
      961 tttatctttt ttagttttta aatatagctt attaaagtca ttaatttctt cattaatagg
     1021 gattctattt tcgattttta ttccatattt ctctaattga tttattttat ctgggttatt
     1081 acttaaaaga tttatacttt ttatgtttaa attttttaat atttgagcag ccatatagaa
     1141 atctctcata tcttcttcaa atccaagcat taaatttgct tcaacagtat cgtaaccttc
     1201 ttcttgaagt ttataagcct taattttatt taaaagacca atacctctac cttcttgctt
     1261 catataaatt aaaactccac ttccattttc cacaattttc ttcatagaag attctagctg
     1321 taatccacaa tcacatttta gagagtggaa cacatctcct gttaaacatt cagaatgaag
     1381 tctaactaga gtattttcta tatttatatt tccataagta agggcaatgt gttcttcatt
     1441 tgaataagta tctctatatc ctatgatttc aaaatttcca tattttgtcg gaaggaaagc
     1501 actagatact ttttctatag tagtttcatt tattttgcgg tattctataa ggtcttttat
     1561 agtgatgatt tttaaattat gcttttcttt gaaaatcatt aaatcatcaa ctcttgccat
     1621 tgtaccatca tctttcatta tttcacagat aagaccaatc tctttaaaac ctgcaagtct
     1681 agcaaggtct actgaggctt ctgtatgtcc atccctgaca agaactccac cagtttttgc
     1741 tattaaagga aagatgtgac caggcgtttt gaaatcttta cttgtagaat tttcatcaca
     1801 gaataatttt acagtttcag ctctttcata tgcagatata ccagttagag tatctgctcc
     1861 atctatagta acagtaaagg ctgtttgaaa tgtatctgta ttttctctaa ccataagagg
     1921 tatattaaga cttttaaatt ttttttcagt ggcaggtaga caaattagac ctctaccata
     1981 tgtagccata aaatttattg attcaggagt agccatttca gctgccatca ataaatctcc
     2041 ttcattctct ctactttcat catcaactac gattaccatt ttcccatttt ttatatcttc
     2101 aatagcttct tcaatagtat taaacatgta attcactcct ttattatttt taaaaaccat
     2161 ttttaaataa aaaatcttta tctatatttg atttatggtt actactatta gaatttaatt
     2221 ccttgtagtt attagccata aaattattaa catactttcc aattacatcg ctttctaaat
     2281 taacgaaatc tccaacattc tttgtcaaga gaatagtgtt aattttagta tgaggtataa
     2341 tagaaacctt aaatatttca tcatctaaat atgatatagt taaacttaca ccatcaatag
     2401 caacagaacc tttgagtatc attgaggata aaagtttttt atcaggtcgt atacttacta
     2461 aaactgcatt ttcatctttt tcaaatttgc agatagttcc tttaccatca acatgacctg
     2521 ttactatatg accaccaaat cttgaagaaa gactcatagc tctttcaaga tttaccttgt
     2581 catttgcatt taataaacct aaatttgtgg aacgaattgt ctccatcata acatcggctg
     2641 taaattcatt ttttccgagg tttgaaacag ttagacaaac tccatttacg gctatactat
     2701 ctccaagatt tgtgccatct aatattttat ttgatagtat ggttactttt ccactcttac
     2761 cattagcagt aatttttcta agtattccaa cttcttctac tatgccagta aacatcctaa
     2821 cctcctatat gaatgtatta acaaaaattt aatttaaaac atctgattct ataagaatat
     2881 cgccatctat caaagttaca ttattgattg ttaactgtgt tgaatctgac aaatgattta
     2941 ttccttctcc agaaacgaat gtaggtgcat ctttaccacc tataatcttg ggtgatagaa
     3001 ataatttgac tttatcaact aacttatttc taaagagact gtcattgaga gtagcaccac
     3061 cttcaactag aacagaatca atgtttaact ctcctaattt atacattaca aactccaaat
     3121 ctactaagtt gttttttgaa ggagaaatta ttgtttcaac attattttct tttaacatag
     3181 ataattttat actttctttg caacatgtga aaactatagt tttactggtt ttatctttaa
     3241 ccaaattact attaagtggc aactttaggt gtgtatctat tactattctt gtaggatgag
     3301 acactttttc ttgattgagc ctacaagtta gtaaaggatt atcgttcaaa actgtattta
     3361 tgccaaccat tatactttgg tatttatttc tgtatttatg agttagatac cttgatgatt
     3421 cattagatat ccattttgat tctagtgatt ttgtggcaat tttaccatct agacttactg
     3481 ctgattttac aatacaaaga ggtcttttgt tttttatatg ataaaaaaat gcctcattta
     3541 aatctcttgc ttcatcttct aatattccca cagtaacatc aatattgtta tcttttaatt
     3601 tttttactcc attaccacaa acaagtggat ttgggtctaa tgtagatatt acaactctct
     3661 taatcttatt ttgtataatt ttatctacac aaggaggcgt tttcccataa tgagaacatg
     3721 gttctaagtt tacataaaga gtagagtctt ttagactttg tttagcactg tttatagcat
     3781 ttacttcagc atgattagag ccaaatttct catgatatcc tttgcctatt atattactat
     3841 ctttaacaat tacacatcca actaatggat ttggatttac aaagccttct ccatttttag
     3901 ccaattcaat agcttttttc atataataaa tatctttttc tttttgattc acaaaattca
     3961 caatatgtac acctcctgtt taattggata atttttaaac aaaaaaccct gagaattaac
     4021 tcagggttta gaataatcta caataaatgt ttaataaatg tagaacaaaa ttgctctaca
     4081 aaaacactca ttaaatatct tcttccatcc agactttact gtcggctttg gaatttaacc
     4141 aaatcaacca agttttacat tggctcgcgg gctataccgc cgattgggaa tttcacccta
     4201 ccccgaagat taagtattaa atttatattt agaatgtatc ataaattatt ttactttgca
     4261 aactattttt ttaaaaaata tatgttaata tataatatag aatgtctata aactttgaaa
     4321 taccacgatt gtgaatataa aaataaaaat ttgaacataa tcaggaaaga agtctaatta
     4381 atttaaatta ggagagtaat atatgaataa aaaactttta gaaatactat caaaatacta
     4441 tggatataca agttttagaa aaggtcagga atctataata aattctatct taagcgaaaa
     4501 agatgtgcta gctattatgc caacaggagg gggaaaatca atatgttatc aaattccagc
     4561 tttgatttta gatggaatga caatagtaat ttctccactt atatcactta tgaaagacca
     4621 agtagatgcc ttaaagacta tgggaattag tgctgctttt ataaatagtt cattaagtag
     4681 caaagaattt aatgaaatat taaataatat tagaaaaaat aattataaaa tactctatat
     4741 tgctccagag agattagatg cacaagagtt tattgagcta ataaataata acaatgtaag
     4801 tcaagttgcg atagatgaag cacattgtgt atctcaatgg gggcatgatt ttaggttgag
     4861 ttatagaagg atttctgatt ttataaaaaa tttgcctaaa agacctatag ttacagcatt
     4921 tactgcaaca gcttcagaag aggtaagaac tgatataata aatttactgt gtttagaaaa
     4981 tccagattat tatataactg gatttgatag agagaattta tcaataaata tagtaaaatc
     5041 atctagtaaa aataagtata ttttagatta tattcaaaat cataaaaatg agtctggaat
     5101 tatatatgtt gcaactagaa aggaagttga aaatatatat aatggtttat ctaagagaaa
     5161 tatatctgta tcaaaatatc atgcaggttt atctaaaaat gaaagaagta aaaatcaaga
     5221 agattttata aatgataatg tggatataat ggtagcaaca aatgcatttg gaatgggtat
     5281 tgataaacct aatataagat gggttataca ttacaatatg cctcaaagta tagaaaacta
     5341 ctatcaagaa ataggtagag ctggtaggga tggagaaaaa agtgagtgtg tacttttatt
     5401 ttctccagga gatgtacata tacaaaaata tttaattgat attggagttg aaaatcctga
     5461 aagaaaatta tttcagcata agaagcttca atacatgatt gacttagttt acagtaattc
     5521 atgctataga aagacaatat tgagttattt tggagaaaat tatatagaca attgcaataa
     5581 ttgtagcaat tgtttagtag agggtgaaat agtagataaa actatagatg cacaaaaagt
     5641 catttcatgt gtagctagaa tgaaaagaag ttatggtgtt actactattg tagatgtgct
     5701 tagaggttct aagaataaaa agattttaca gcttggatta aatactttgt ctacatataa
     5761 cattatgaga gattattcta gtgaagactt aaagaatttt gtaaatacat tggtttctca
     5821 tggtttttta gatttagttg agactctagg caatggaaat agaggtagtt ttcctactat
     5881 aagattaaat gagatgtcta tgaaagtttt aaaaggtgaa gtgaaagtag agtttaaaga
     5941 aattgttatg acaaaatcat tggaagtaga ggatgagtta tataatgctt taagagaact
     6001 tagacattca attgcaagtg aagaaaggat agctccatat atggtatttg gagatggtac
     6061 acttagagcc atgtctagta gttatccaat taataaagaa gaaatgctag atatctctgg
     6121 agtaggagaa attaaatacc aaaaatatgg tagagatttt gaagcagtaa ttaaagaata
     6181 tgtcgaaaaa ataatataaa taaaaaaata gatgaaaaaa atgtcgattc aaagaacgtt
     6241 aatagtgatt tcttagaggt taatacagat aaagttttat atgaaaaact gttagtcatt
     6301 agagaagaat atgcaacaaa ggaaaaatta cctgcatata tgattttagc caataaggct
     6361 ttgaaagaaa taagtggaag atatccactt gatgaagaac aattaaaaga tatttctggc
     6421 ataggtggag taaaatttga aaaatatgga gctagtattt tggcagaggt taataaatat
     6481 gtaaaagaaa ataatattaa tgttatttgg gagaaaaagg gcaaaaggaa gttaatatta
     6541 gatggagaaa gtagaaaaaa taatgaaata gcattagatt tgctaaatca aggaaaagat
     6601 atacaaagta tcagtcaaga aatagaagtt tcactgtcaa ccattattgg atatgtgcat
     6661 gactatgtaa aggatggaca tagtatatca tttgaattag gactagaaaa tttttataat
     6721 gaagataaaa agaagatgat tttagaagtt tgcgaaaaag ttggctatga taatttaaat
     6781 aacataaaaa gaaaacttcc agattcaata aagtatgaaa atataagagc tgtgatactt
     6841 gactcttatc ttgaaaactt aaaaaataat attatagcag agtaattttt aacttaataa
     6901 aaaataaaat ttgtattatt gtgttgaact aataattttg ctgtgttata ctgaatttgt
     6961 aaaaataatg aaaaattaga gctaggggcg ctagaattgg ctagctgaga gataaagccg
     7021 taacttacaa accctaataa cctgatcaag ataatgcttg cgaagggaag ctttttaata
     7081 taattttatt atataaatag gcaaattatt caatgttagg agaaatttgt ctaagtgtat
     7141 atacgattat aagagtgctt tccaaacgag gaaaagcact ttttttattt tcaaaaacta
     7201 taactttaat cttggaggat tgtaatatga actatacaac acaaatggat gctgctagaa
     7261 aaggcataat aactaaagaa atggaaatcg tttctcaaaa agaacaggta gatgtaaatg
     7321 aattaagaga attaatagca aatggacaag ttgttatacc agctaataaa aatcataaat
     7381 ctttaagtgc agaaggtgta ggtaaaaatt taagaacaaa aataaatgta aatctaggaa
     7441 tttcaagaga ttgtaaggat atagaaaaag aacttgaaaa agttagagta gcaatagaca
     7501 tgaaagctga agctataatg gatttaagta attatggcaa aactagagaa tttagagaaa
     7561 aggttgttga aatgtcacct gcaatgatag gttcagtacc tatgtatgat gcagtaggat
     7621 atttggaaaa agaattaaaa gatataacag aagaagagtt tttaaatgta ataagacaac
     7681 atgctattga tggagtagac tttattacta tacatgcagg tcttacaaga agtgtttgcc
     7741 aaaaaataaa aaatcatgag agattgactc atatagtatc tcgtggaggt tctttattgt
     7801 ttgcatggat ggaattaaat aataaggaaa atcctattta tactaatttt gataaaatat
     7861 tggatatatg tgaagaatat gatgttacat tgagtttagg agatgcttgt agaccaggtt
     7921 gtataaaaga ttctactgat ggtgttcaaa ttcaagaact tgtagtatta ggtgaactta
     7981 ctaaaagagc atgggaaaga aatgtacaag taatgataga aggtcctgga cacatggcta
     8041 ttgatgaaat agaagcaaat gtagtattag aaaagagatt atgccatgga gcaccttttt
     8101 atgttcttgg accattggtt acagatatag caccaggtta tgaccatata acaagtgcaa
     8161 taggaggagc tttagcatgt gctaaaggag tagatttttt atgttatgta actccagcag
     8221 aacatttaag attgcctaat ttagatgata tgaaagaggg tataatagct gcaaagatag
     8281 ctgctcatgc aggagatata gctaaaaatg ttaaaggtgc tcgtgaatgg gataataaga
     8341 tgagtaaagc tagagctgat ttagactggt gtgagatgtt tagacttgca atagaccctg
     8401 aaaaagctaa gagatacaga gatgaatcaa ctcctactca tgaggatagt tgtactatgt
     8461 gtggaaaaat gtgctcaatg agaacagtta agaaaatatt aaacaatgag gaacttaatc
     8521 taatataatt tttggctagt atgactggaa taaaaataag ctgaaaagag gaggtgattt
     8581 agtgaaggtt aatgggaagg aaattgaatt tgaaaaagat ttgactgtta tagatttatt
     8641 aaataaatat aatttaaaaa gtgatagagt tgtagttgaa gtgaatttag agataattga
     8701 agaatctaac tacaatacat atgtattaaa agacgaggac attgtagagc ttattagctt
     8761 tattggaggt ggttaaaata aaaatatttg taaatgaatt attaacagat gttgaggaaa
     8821 atacaactgc ttataaagtt agagatagct ataacaataa atgtgatgta ttggtgttaa
     8881 atggatatcc aattaaaaca gatatgaccc tttgtgaaaa tgataaatta acacttatac
     8941 aaaaaggagt taagccatca cttgatgaat tggaaagctt gttgattgct agacatactc
     9001 caaatataca taataaatta aaaaaaggga aagttgctat attgggattg gggggacttg
     9061 gttccaatat agctatctct ttagctagaa taggagtggg agaactttta cttatagatt
     9121 atgatgttgt agaaccatct aatttaaata gacagcagta ttttatagat gatataggaa
     9181 aactaaaaac tgatgccatg atagaaaata taaaaaaaat aaatccattt ataaaattaa
     9241 ataaacgaga tattttttta aacaagaaca atatggatac tattaaggat tcagatttaa
     9301 taattgaggc ctttgatgat gcttcatgta aagcacaggt atgtaattat gtattaataa
     9361 atttaaaaga taaatattta atagcatcat ctggtatggc aggttactat gattcaaata
     9421 taataactac taagaagata aaagacaggt tttatatatg tggggatttt gtgaatgaag
     9481 ctaaatttgg tgaagggctt atggctccaa gggttgccat ctgcgcaaat catatggcaa
     9541 atttggcaac gcaaatactt atagatatgt aaatattaaa attagatata aaaaagattg
     9601 aatattaaaa aaatttaacg tggagggaaa taatatggat aaattggtac ttggtggaca
     9661 tgaatttaat agcagattat tggttggaac aggtaaatat ggttcaaata atatattgcc
     9721 tgaggtaata aaagaaagtg gaagtgaaat aataacaatg gcacttagaa gagtggattt
     9781 agacaataaa caagaaaaca tattaacgta tattccaaaa gagatgacaa tacttccaaa
     9841 tacatcagga gctactaatg cagaagaagc tgtaagaata gctagaatat ctagaaaaat
     9901 gggatgtgga gattttataa aaatagaagt aatatcagat actagatatt tacttcctga
     9961 taatgaagaa actataaaag ctacaaagat acttgctgat gaggggttta tagttcttcc
    10021 atatatgaca ccagaccttt atgctggaag aagacttata gaagctaatg cagcggcagt
    10081 tatgccactt ggagctccaa ttggttcaaa tagaggtctt caaatgaaag aaatgataag
    10141 aataatgata gatgagttgg atataccaat aatagtagat gcaggtattg gaaaaccatc
    10201 tcaagctatg gaggctatgg aaatgggagc tgatgcagta cttgtcaaca ctgctatagc
    10261 ttcagcagga gaccctgtac aaatggctag agcatttaaa ttagctgtag aaggtggaag
    10321 agaagcatat attgcaaaaa caggaaatgt gtcagaattt gcaaatgcat cttctccttt
    10381 aacaggtttt ttaggcaatt tatagaaagt ggtgattggt gatgagtttt tatgatgtaa
    10441 tagaaaaata tagggatttt gattttgatg gatatttaaa taatgttact gataatgatg
    10501 ttttaagaag tttatcaaaa gacaagcttg aagattttga tatattaaat ttgctttcta
    10561 aaactgcagt aaaacattta gaagatatgg cacaaaaagc acataaatta agtgttcaat
    10621 actttggtaa aacagtatgt ttatatacac caatgtatat agcaaattat tgtgttaatc
    10681 aatgtgttta ttgtagctat aatataaaga gtggaataaa aagaaaaaaa ttaactatgg
    10741 atgaaattag agaagaggga gaagcaattt caaaagaagg tttcaaacat ctacttgttt
    10801 tgactggaga aagtagtttt cactcaagtg tagaatatat aggtgaggct atagaaatat
    10861 taagagagaa atttccctct ataggtatag aagtttatcc aatggaagta gaagaatata
    10921 agtacattgt agataaaggt gttgaaggat taacagtata tcaagaaact tatgacgagg
    10981 aaatatataa gagagtacat ataaaaggcc caaaatcaaa ttataaattt agactagatg
    11041 ctcctgaaag aggggcaaaa gcaggtatga ggactttatc aataggtgca cttttagggc
    11101 taaatgattt tagaaaagaa acttttttta caatattgca tgggaaatac ttaaaaacga
    11161 aatatcctca tattgagctt tcatattcaa caccaagaat gagacctttt aaagggtgtt
    11221 ttgaggaatt ggtagatata agtgatactg atttagttca agctatggta tgtatgagat
    11281 tatttgaccc tcatgcagct ataaatatat ccactagaga aaatttagaa atgagaagtc
    11341 atataatacc tttaggagta actaaattga gtgcaggtgt atctactgat gtaggaggtc
    11401 attctcaaga tgaacatgat actgctcaat ttaagataaa tgatgaaagt actgttaaag
    11461 atgtggagaa aatgctaaac tcaattggtt atcagcatgt gtttaaagat tgggaaagat
    11521 tttaaatgta tctgataaca aacagaaaat tatgtagtga ggaacgatat ttagaagtta
    11581 ttaaagagtc tatattgagt ggtgtagaaa atataataat aagagaaaag gatttagaat
    11641 atcaagagct aagaaaatta tatatgaaaa taaaaactaa aatcaattgt atagattttc
    11701 aagagcaaat atcagatgaa agtttgaaaa ctaatataaa tcaaaaagag tgtagaaata
    11761 aattcaaggt taattttata ataaatagta acattgaatt ttttgaaaaa gtggattgtc
    11821 aaggtatcca tcttcctttt aaattattct tgaatttaat tgaaaataag tataatttta
    11881 atgaaaataa aatactagga ttatctttac ataaagtaga ggaagtagat tatttagaaa
    11941 aattaataag aaatcaaaat ataaaaatag attacataac attatcacat atatatgaaa
    12001 ctaaatgtaa agaaggatta aatccaaaag gaattgagct tttaaaagaa gctaaaaaga
    12061 ttactgatat taaaataatt gcacttgggg gaattttacc atctaatgtc aaggaaacat
    12121 taaaatactg tgatgatttt gctataatgt caactataat gaggtctaaa gatattaaaa
    12181 aaaccatatc aaattataat gaaaagttga attagtaaat atagtatatt gaatttttaa
    12241 cttaaataaa aataaaaaag ttatctttta aattttaaaa ggtagctttt ttattttata
    12301 tctttgctaa taaaaaattg taaaaaggga aaactttagt cagagagatt aaacaatatc
    12361 ctagaaagat ttaaaattta gtaaagtatg gaggacatta taatgactga cagtaaaaag
    12421 aaacgattta ttataccaca cacttttaca ataatatttt tactaatagt cttgatggca
    12481 atattgactt ggatagtacc aagtggtgaa tttagtagag aagatgtaga aggtagaatg
    12541 gtagttgtac cagggactta tcaaagtgta gaaagtaatc ctcaaggatt tgcagatgtt
    12601 tttaaagcac caatagaagg ctttatcgat tcagctgaag ttgtaggttt tgttttaata
    12661 gttggaggtg cttttggtat tgtaaatagg actggagcta tagaagcagg aatagcttcg
    12721 gttatctcta agtttaaggg aaaagaactt cttataattc caatatcaat gattttattt
    12781 ggacttggag gtacaacatt tgggatggca gaagagacat taccatttta tatgatattt
    12841 gttccactca tgacatcctt gggatatgat tctctaacag caatagcaat tgtatttata
    12901 ggagcagcag caggagccgc cgcttcaaca ataaatccat tttcagttgg tattgcacag
    12961 gcactagctc aacttgctcc tggttcagga gtaacttaca gagtagttat ttttatagca
    13021 tatatactaa taagtatagc atttgttatg tactatgcta agaaggtaaa ggaaaatcct
    13081 gaaagttcaa tagtatatga aatagataaa aataataaat caatacttaa tcaaacttca
    13141 acagaaataa aagaatttac ttttaaagaa gtatctgttc ttgctatatt tggaataggg
    13201 atggcaataa tgatttgggg tgttttaagt caaggatggt acattccaga aatatcaatg
    13261 tgttttgctg caataggtgt gctttctgga ttggttggta gattatctca aattgaaatc
    13321 tcagaaagtt ttatagatgg agcaaaagat ttagcatctg cagctcttgc tatagctttg
    13381 gctcgtggaa tcgtaataat tgctcaaaat ggatttataa tagatactat attaaattcc
    13441 gcagcagcct ttctaggtgg gcttccaaag gttatatttg tatatttatc atttttcttg
    13501 gaagctgcat tggcattttt aattccatca tcttcaggtc ttgcttcact tacagtacct
    13561 gtacttgctc ctcttggtga tttggttaat atatcggctc aagtgatagt aaccgcttat
    13621 caatttggtg tgggtcttac aaactttata actccaactt caggagtact gatgggagca
    13681 cttgcagtag cccatattcc attttcaaaa tgggtaagat ttataatgcc tatcttgttg
    13741 attttgacag ctgtatctct agtcttttta acaataggta tttatatagg gttttaatta
    13801 agtgtagttt tatttaagat atttagtaat ggtataaaat gataatatgt tttcaataaa
    13861 ttgccactaa tttaattagt ggtaatttgt tttttgtatt taaaaataaa tatatttact
    13921 tgtattttga attaatatct acttagacat tgttttaatt gttatatttt catttaatta
    13981 agcattgatt tatcattttt tatatttcat ataacaatgc aaaaaataat ttttatatag
    14041 taaatgacaa aagtttacaa taaatgtata ttttcttact cattccttaa aattactcat
    14101 ttagtttaat aactctcatt tcatatgtaa agttggtaaa aaaattaaaa ttaaaagtaa
    14161 aaaactaaat aaattaatgt taatttgaaa tatatatgaa ggtttttgga gaatacttac
    14221 ttatgatagg aaaaaatgtt aaaataatag tgtaatcaaa tataaaggac tgaaataatt
    14281 aacagttatt aaatattagg agtgtaaaaa tttatgggat taaaagaatt tgattttatt
    14341 gaagagtcta ttgatatgtt gaggacaatg tcaccaacat tagaaactat atcagatgaa
    14401 atagaagagt attttgaaaa tatcttggat gaaaagaatc aagaatatat aaatgtaacc
    14461 tctagaataa aatcagaatc aagtttaaga gaaaagataa ttagaaatag atatttaaaa
    14521 aaatatggag aagcaagtaa tcttattcat aatgtttctg acttaatagg cctaagaatt
    14581 gagtgtagat ttattgagga tgaaaacaaa atatatagac ttttgagaag atattttaat
    14641 aaaacagatg acaaaataaa ctattataat aaagagaata agaatattaa attaaaacta
    14701 tctgagagac aacccaataa gcaaaaaaat ggatttgaaa tatataaaat agatggagtt
    14761 tttgcgtatt tagata
//
LOCUS       DAEPKC010000098        14762 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.098, whole genome shotgun sequence.
ACCESSION   DAEPKC010000098 DAEPKC010000000
VERSION     DAEPKC010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14762)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14762)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14762
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.098"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..372
                     /locus_tag="KR294_003026"
     CDS             <1..372
                     /locus_tag="KR294_003026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilus assembly protein PilM"
                     /protein_id="HBH0241085.1"
                     /translation="FDILQKLINLNLIENFSEEGVFIECKKSQLIINITKDKKIRETY
                     LLSKEGKSYEFIKRLLRDFKYVYYYGIENCFIEEYFKYTDKSIEVNPLRLKDKVKVEN
                     NFDADLEDNRINYISNIGMII"
     gene            373..816
                     /locus_tag="KR294_003027"
     CDS             373..816
                     /locus_tag="KR294_003027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241086.1"
                     /translation="MKVDKTINFLNGFKKTKPCNKIYKIIIVLILTCILFKSFMYVKS
                     INELEDYISQNKLVDKSRHTLPTTDKTREKFSKIKLNEIKKIYETIGINIITKISIDK
                     NKLEIEGVCSDLDVLNNLRKIKYIKYYYIDSIVRDGEYYRFRIKS"
     gene            831..1415
                     /locus_tag="KR294_003028"
     CDS             831..1415
                     /locus_tag="KR294_003028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241087.1"
                     /translation="MRLNNREKNLLKILLILVIILASDIAVSYLEENLTSLKNEKQNI
                     INKINNQDNYQIKDNKHIDDKYIESVESNKNEELKNNFNNSFLDKKTNKDIVLLVENE
                     LRDIVNVEYINQESSLDNHNKKQVNLEIKVNGELANLLKLEGVMKKLRLNNKLEKIEI
                     NKLKVNNFDVQNIPNEYKQEKDNIVECKMTVRVI"
     gene            1668..2705
                     /locus_tag="KR294_003029"
     CDS             1668..2705
                     /locus_tag="KR294_003029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SEC-C domain-containing protein"
                     /protein_id="HBH0241088.1"
                     /translation="MLGRNELCPCGSGKKYKKCCLNKDIVSERACRKTELSQKQYTDL
                     YSKLYDYSRQDKFKEECEKAKEMFYIMQNDSVNEKFERFFNTYLIQDHIMENKKVMTV
                     GFLEENGANLSQSEVSILKSMFESYVSIYEVKEVSAGKIVLKDCLSGNELCTEDVKLL
                     RSFKIGSCMIARIVDIEGTNILIDITISISNEVKDIILKDIMNLFNQYQDVYKDMKSF
                     LIYHTHILYKYIQQLLDPSIAEYLKRERDKNDTKVNSENELAEEECKVLDTLKENVEK
                     ENIDACIEFWNEYKKNHENIKGAENGWAAAVEYYVKKEAGQPITQVQISKKYDISSST
                     LGKRYKDLKIS"
     gene            2786..3151
                     /locus_tag="KR294_003030"
     CDS             2786..3151
                     /locus_tag="KR294_003030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241089.1"
                     /translation="MSLSLGNAIAVSTNFIKSNPAVPVYNGEEIYAVIYHIEIGYNNG
                     VSPDTKQYIIIDYKEFDLSMDKKNELINIAKEYCKSKGIVENENLEINLLDNEEAENF
                     LEKVFNNMKVIRGLITKKG"
     gene            3156..3473
                     /locus_tag="KR294_003031"
     CDS             3156..3473
                     /locus_tag="KR294_003031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241090.1"
                     /translation="MDYIGIENITPYENTYEFSVYEYDDEITLGSEKLYVCELRVVLI
                     KVNSLYVERLHKSVEAMVLVKNLKKDLDKTLVVNKIKNFVLDEIWVENLVKENIEVIF
                     VES"
     gene            3521..5125
                     /locus_tag="KR294_003032"
     CDS             3521..5125
                     /locus_tag="KR294_003032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241091.1"
                     /translation="MLRVSNVKLGIDKDISLLKDVILKKLKIKEKNLVKYSIYKESID
                     ARKKGKMEFVYSVDVEVKDENKILNSKIKDVTKIKEIRYVNVPVGDKKLKNNPLVIGS
                     GPAGLFAGLLLAQMGYEPIILERGLDVDSRTKDISDFWTTRKLKNNSNVQFGEGGAGT
                     FSDGKLTTRIKDIRCRKVLEELVQFGAPDEILYSHKPHVGTDILKNVVKNIRNEIISL
                     GGQVRFNSKVTDIVVSNDSIQSVIINDTEKIDTDTIILAVGHSARDTYEMLYSRGIKI
                     VQKPFAIGARVEHPQDLINKAQYKDFYNHPRLGAADYRLIEHVSNGRTAYTFCMCPGG
                     SVIASASNDFEIVTNGMSEHARDKINANSAFLVNVTPEDFKSDNPLAGVHFQQKYEKL
                     AFELGGKNYNAPVQLVGDFINNKTSLNLGSVEPSYRPGYTLTNLSECLPSFVTETMRE
                     AFISLDKKLNGFAMYDAVLTGVETRSSSPIRIVRDENTLESVSIKNLYPCGEGAGYAG
                     GIVTAAVDGIKCAEKIIQKYTNNTKI"
     gene            5249..6877
                     /locus_tag="KR294_003033"
     CDS             5249..6877
                     /locus_tag="KR294_003033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HBH0241092.1"
                     /translation="MNIIISLMGGLGLFLYGMNLMGEGLQKSAGTKLKKIIKLLTSNL
                     FMGVLVGTGVTAVIQSSSATTVMVVGFVNAGIMTLKQAIGVIMGANIGTTVTAQLVSF
                     DLTGMAPVALGVGIILYLFGNKPRIKNIAEILIGFGILFTGMDFMKMAVEPLRDYQGF
                     TDLLVTFGRYPLLGLLLGFGITAIIQSSSASMGMLVALAAEGLVPLSAALPILYGQNI
                     GTCVTSLLSSIGANKNARRAAMMHLIFNVLGTVIFLIFLNKPVVSMVTSWDPSNVARQ
                     IANTHTLFNIISVLILLPFTSLIIKLAIKLVPDRAGDIDEDETKTIKYIDDRMIETPS
                     IALANTIKEALRMGEKAKESLNASMEALVEHSTEKIDKTYRRERLINDLQKAILNYLL
                     KLSKAALDDDSREVVDTLFNTVNDIERIGDHAKNIAELSQVAIDSNIYFSEEGQSELD
                     VMYNRVVSAYTYALESMRSDNVDLACKVIKIEEQVDIMEKSCRANHMYRLNNNLCSIE
                     NGVIYLDVISNLERISDHAVNIAQQVIAKRLGND"
     gene            7142..8491
                     /locus_tag="KR294_003034"
     CDS             7142..8491
                     /locus_tag="KR294_003034"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HBH0241093.1"
                     /translation="MGKINFDYSKATEFFCQNEIDVMQPYVDVAHDMLHNKTGLGNTF
                     LGWIDLPKNYDKEEFDRIKKSADKIKSDSDVLLVIGIGGSYLGSRAAIDMVSHSFRNG
                     LKKEQRKAPEVYFVGHNISSTYIMDLLDIIEGKDISVNVISKSGTTTEPALAFRIFKD
                     YLEKKYGKEEARKRIYATTDASKGALRQLATEEGYETFVIPDDVGGRFSVLTAVGLLP
                     IAAAGLDIDAMMKGANDAREAFQNPDLKSNDSYRYAVARTILHRKGKDVELLVNYEPQ
                     LHYVSEWWKQLYGESEGKENKGLFPASVDFSTDLHSMGQYIQDGKRLLFETVLNVENC
                     KRNITISSEEVDLDGLNYLAGKTVDFVNHKAFEGTLLAHTDGKVPNLVINIPQLDEYN
                     FGYLVYFFEKACGISGYLLGVNPFDQPGVEAYKKNMFALLGKPGYEKEKEELEKRLK"
     gene            8647..9726
                     /locus_tag="KR294_003035"
     CDS             8647..9726
                     /locus_tag="KR294_003035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HBH0241094.1"
                     /translation="MSRRKKGISLVILVAIISSILSSFLTIILVKDNLVSKSTGSSTP
                     IVVNDDGKSQNIYQAVAEKATPSVVGITTTSVDTSNMFAIPTETQGVGTGIIVDSNGY
                     ILTNSHVISDGQATSVNVLFNDGSTTSGKVVWFDQQLDLAIVKVDKTGLTPAEFADSD
                     KVKVGDISIAIGNPLGLDFQKTVTQGIISGLDRTIQTEKTNMTGLLQTDASINAGNSG
                     GPLLNQKGQVIGINTAKASQAEGLGFAIPINTAKSIVEEVIKNGKYEKVTLGIKGTDV
                     SNYEAATGTKLSTDKGVYVAEVISGSSAEKAGVKVGDIITKVGDTDITGMNDLNKKLY
                     TFSKGASTKITVNRGGKAVTINVNF"
     gene            10071..10979
                     /locus_tag="KR294_003036"
     CDS             10071..10979
                     /locus_tag="KR294_003036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HBH0241095.1"
                     /translation="MNPLVINLQKCSIHDGPGIRSTVFFKGCPLECVWCHNPESQTYT
                     KQVLYNEERCSKCEACINICPHKAIYKGETKICLDQDKCEFCETCLDYCVNNAREIVG
                     QEYSVRDLVKEIEKDRIFYEESGGGVTLSGGEVMAQDMDFICGVINMCKSKGIHVAID
                     TCGYAKSENYERVAKCADLFLYDIKLIDEDKHIKFTGKSNDLILKNVKILSELGANIN
                     IRIPLIVGVNVDDENLEVKKMIEFLKPLNIQAVSLLPYHNIGKHKYDKIYKKYEGEEL
                     QRPSEEKLEEIKRLFEASNFNTKIGG"
     gene            10984..13353
                     /locus_tag="KR294_003037"
     CDS             10984..13353
                     /locus_tag="KR294_003037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HBH0241096.1"
                     /translation="MARGTFERTKKLREESINAEPHISIERAVLMTEAYKKYEGSVEI
                     PVLRALSFKHYIENRTLSINDGELIVGEKGDSPNGAPTYPEICCHTMEDLEVMHNRDI
                     INFSVSEEARKIHKEEIIPFWKKRQTRDKIINAMTPEWLAAYEAGMFTEFMEQRAPGH
                     TVCGDTIYKKGFLDLKKDIEARLKELDFLNDLDAYNKKADLEAMAIACDAMVILGKRY
                     AEKARQMAEEETDEAKKQDLLLIAETCDVVPAHKPETYHQAIQMYWFVHIGVTTELNI
                     WDAFTPGRLDQHLNPFYERDVENGILDRDRAQELLECLWVKFNNQPAPPKVGITLKES
                     STYTDFANINTGGINPDGQDGVNEVSYIILDVMDEMKLIQPSSNVQISKKTPQKFLKR
                     ACEISRKGWGQPAFYNTEAIVQELMEAGKTIEDARLGGTSGCVETGCFGKEAYVLTGY
                     MNIPKILELTLNNGYDPISKKQIGIETGDPRNFQSYEELFEAFKKQLHYMIDIKIEGN
                     AVIENICAKHMPCPLMSTIVDDCIEKGKDYQRGGARYNTRYIQGVGIGTITDSLTAIK
                     YNVFDKKKFDMDTLLKALDANFEGYEAILNLVSNKTPKYGNDDDYADEIMQEIFNAYY
                     NEVTGRPTVCGGEYRVDMLPTTCHIYFGEIMGASPNGRLCAKPVSEGISPEKGGDTNG
                     PTAVIKSCAKMDHIKTGGTLLNQRFAPSVVQGEKGLDNMANLVRAYFNMDGHHIQFNV
                     FDKNVLLEAQKNPQDYKDLIVRVAGYSDHFNNLSRTLQDEIIGRTEQTF"
     gene            13678..14481
                     /gene="proC"
                     /locus_tag="KR294_003038"
     CDS             13678..14481
                     /gene="proC"
                     /locus_tag="KR294_003038"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HBH0241097.1"
                     /translation="MKTLGFIGSGNMGSAMIGGIVQSGLVKAEDITVSDLSQVALDKV
                     KEEFGVNTTTDSKVAVTNSDVVIVALKPNICEKALTPLKELIDANKIIVSIAAGKTIE
                     SLESFIGSDKKIVRVMPNTPALVGEGMSALCKNSNVTDEELNMIKALFESFGEAEIVS
                     EYLMDTVTGISGSSPAYVFMFIEAMADAAVLAGMPRQQAYKFASQAVMGSAKMVLETG
                     KHPGELKDMVCSPAGTTIEAVKVLEEEGFRAAVIKSIVACIDKSKDMSK"
BASE COUNT         6072 a         1489 c         2694 g         4507 t
ORIGIN      
        1 tttgatatat tacaaaagct tataaactta aatttaatag agaatttttc agaagaaggg
       61 gtatttatag aatgtaaaaa aagtcagtta attataaata taacaaaaga taaaaaaata
      121 agagaaacat acttgctatc aaaagaggga aaatcatatg agttcataaa aagattatta
      181 agggatttta agtatgttta ttactatggt atagaaaatt gttttattga agaatacttt
      241 aaatatacag ataaatctat tgaagtaaat ccattaagat taaaagataa agtaaaagta
      301 gaaaataatt ttgatgcaga tttagaagac aataggataa attatataag taatatagga
      361 atgattattt aagtgaaagt ggataaaacg ataaattttc ttaatggatt taaaaaaact
      421 aaaccatgta ataaaatcta taaaataata atagtcttaa ttttaacgtg tattttattt
      481 aaatcattta tgtatgtgaa atctataaat gaacttgaag attatataag tcaaaataag
      541 ctagtggata aatcaagaca cactttacca acaacagata aaactagaga gaaattttct
      601 aaaataaaac ttaatgaaat aaaaaaaata tatgaaacaa ttggaataaa tattattact
      661 aaaatatcga tagataaaaa taagctagag attgaaggtg tgtgtagtga tttagatgtt
      721 ttaaacaatc taaggaaaat aaagtacata aaatattatt acatagacag tattgtaaga
      781 gatggagaat attatagatt tagaataaaa agttagatgg gtgattattt ttgagattaa
      841 ataatagaga aaaaaatcta cttaaaatat tgttaatatt agttattata ttggcaagtg
      901 atatagcagt aagttatttg gaagaaaact taactagttt gaagaatgaa aagcaaaata
      961 taataaataa aataaataat caagataatt atcaaataaa ggataataag catatagatg
     1021 ataaatatat agaaagtgtt gaatcaaata aaaatgaaga attaaaaaat aattttaata
     1081 actcattttt agataaaaaa acaaataaag atatagtgtt attagtagaa aatgaactga
     1141 gagatattgt gaatgtagaa tatattaatc aagaaagtag tttagataat cacaataaaa
     1201 aacaagttaa tttagaaata aaagttaatg gagaacttgc aaatttgttg aaacttgaag
     1261 gtgtaatgaa gaagttaaga ctaaataata aacttgaaaa gatagaaatt aataaattaa
     1321 aagtcaataa ttttgatgtt caaaatattc caaatgaata taaacaagaa aaagacaata
     1381 ttgttgaatg taaaatgaca gttagagtca tataacaaaa aagaatagat aaagtaaaaa
     1441 actattatca attaataaaa ttttatagag gaattagttt tacgataatt catttctaca
     1501 agagggattg ttgatgattt tatcgaaatc ctaattaaag ttaatatatt gtaccaaaat
     1561 ataagtgaat ttaatagaat atttacttat actatagatt gattaataaa aaaatggtat
     1621 aataacaaat tgtactttaa tttaataata agggagtgga agtcatattg ttagggagaa
     1681 atgagctatg cccttgtgga agtggcaaaa aatacaagaa atgttgttta aataaagata
     1741 ttgtttcaga aagagcatgc agaaaaactg aactttcaca aaaacaatat acagatttat
     1801 attcaaagtt atatgattat tcaagacagg ataagtttaa agaagaatgt gaaaaagcta
     1861 aagaaatgtt ttatataatg caaaatgata gtgtaaatga aaaatttgaa agatttttta
     1921 atacttattt aatacaagac cacataatgg aaaataaaaa ggttatgaca gttggttttc
     1981 ttgaagaaaa tggtgcaaac ctaagtcaat cagaagtatc aatattaaaa agtatgtttg
     2041 aatcatacgt aagtatttat gaggtaaaag aagtttctgc tggaaaaata gtattaaagg
     2101 actgtttaag tggaaatgaa ctttgtacag aagatgtaaa acttctgaga agttttaaaa
     2161 tcggaagttg tatgatagct agaatagttg atattgaagg aactaacata ttgatagata
     2221 taactataag tatatcaaat gaggttaaag atataatttt aaaggatatt atgaatctat
     2281 tcaatcaata tcaagatgta tacaaagata tgaagtcgtt cttaatttat catacacata
     2341 tactatacaa gtatatacaa cagcttttag acccaagtat agctgaatat ttaaagagag
     2401 aaagagataa aaacgataca aaagttaatt cagaaaatga attagctgaa gaagaatgta
     2461 aagttttaga tactcttaaa gaaaatgtag aaaaagaaaa tatagatgca tgtatagagt
     2521 tttggaatga atataagaaa aatcatgaaa atataaaagg agctgaaaat ggttgggcag
     2581 ctgctgttga atactatgtt aaaaaagaag caggacaacc tataactcaa gttcaaatat
     2641 caaagaaata cgatataagc tctagtacac taggaaagag atacaaggat ttaaaaatat
     2701 cttaattaat tataaaaagc tttaagtcat agataaagaa tctatagtat aatatatgta
     2761 taatgtttag aaagaggtat taataatgag tcttagttta ggaaatgcaa ttgctgtatc
     2821 aacgaacttt ataaaatcta acccagctgt acctgtgtac aatggagaag aaatatatgc
     2881 agttatttat catatagaaa taggatataa taatggtgta tcacctgata ccaaacaata
     2941 tataataata gactataaag agtttgattt atctatggat aaaaaaaatg aactaataaa
     3001 tattgctaaa gagtactgta aatctaaagg tattgtagaa aacgaaaacc ttgaaataaa
     3061 ccttttagac aatgaagaag cagagaactt cttagaaaag gtgtttaata atatgaaggt
     3121 tataagaggt cttataacta aaaaaggata aataaatgga ctatatagga atagaaaata
     3181 taacacctta tgaaaataca tatgaattta gtgtatatga atatgatgat gaaatcacct
     3241 taggtagtga aaagttatat gtatgtgaat taagggttgt attgattaaa gttaattctc
     3301 tgtatgttga aagattgcat aaatcagttg aagcaatggt cttagtaaaa aacttgaaaa
     3361 aagatttaga taaaacactt gttgtaaaca aaataaagaa ttttgtgcta gatgagattt
     3421 gggtagaaaa tctagtaaaa gagaatatag aagttatatt tgtagaaagc taggaataac
     3481 cctagctttt ttatattaca atctaagaga ggaaaacaat atgttaagag tatctaatgt
     3541 aaaacttgga attgataaag atatatcttt attaaaagat gttatactta agaagctaaa
     3601 aataaaagaa aaaaacttag tcaaatatag tatatataaa gaatctatag atgctagaaa
     3661 aaaaggaaaa atggaatttg tttattctgt agatgtagaa gttaaagatg aaaataaaat
     3721 acttaactca aaaataaaag atgtaacaaa aataaaggaa atcagatacg taaatgtacc
     3781 tgtgggtgat aaaaaattaa agaataatcc tttggtaatt ggtagtggac cagctggttt
     3841 gtttgcaggt ctgcttttag ctcaaatggg ttatgaacca atcatacttg aaagaggtct
     3901 tgatgtagac agtagaacca aagatataag tgatttttgg acaactagaa aattaaaaaa
     3961 taattcaaac gttcaatttg gagaaggtgg agcaggaact ttttcggatg gtaaacttac
     4021 aactagaata aaagatatac gatgtagaaa agtattagaa gagttagttc agtttggggc
     4081 accagatgaa atattatact cacataagcc acatgttgga acagatatat taaaaaatgt
     4141 agttaaaaat ataagaaatg aaataataag tttaggtggt caagttagat ttaattcaaa
     4201 agtaacagat atagttgtat caaatgattc tatacaatct gtaataataa atgatactga
     4261 aaaaatagat acagatacaa ttatattagc tgttggacat agtgcaagag atacttatga
     4321 aatgttgtat tcaagaggta taaaaatagt tcaaaaacct tttgcaatag gagctagagt
     4381 tgaacatcca caagatttaa taaataaagc acagtacaag gatttttata atcaccctag
     4441 gttaggagct gcagattata gacttataga gcatgtttca aatggaagaa cagcatatac
     4501 tttttgtatg tgtccaggag gtagtgtcat agcatctgca tcaaatgatt ttgaaatagt
     4561 tacaaatggt atgagtgaac atgcaagaga taaaataaat gcaaatagtg catttttagt
     4621 aaatgtaacg ccagaagatt ttaagagtga taatccacta gcaggtgttc atttccagca
     4681 gaagtatgaa aaattagctt ttgaattagg tggaaaaaat tataatgcac cagttcagct
     4741 tgttggagat tttataaaca ataagacttc tttgaattta ggaagtgttg agccatcata
     4801 tagaccagga tatacactta caaatttaag tgaatgtttg cctagcttcg taacagagac
     4861 tatgagagaa gcgtttatat ctcttgataa aaaattgaat gggtttgcaa tgtatgatgc
     4921 tgttttgacg ggagtagaaa ctaggtcatc atcaccaata agaatagtga gagatgaaaa
     4981 tactttagaa tcagtgagta ttaagaatct atatccatgt ggtgaaggtg ctggatatgc
     5041 aggtggtata gttacagcag cagttgatgg tataaaatgt gcagaaaaaa taatacaaaa
     5101 atacaccaat aatacaaaaa tttaacataa acttaatgat tttttaatat ttaacatgaa
     5161 tttaacatta tcactcctat aatttgataa aatacaatag gttataaaat ttttagatac
     5221 agtaatctct ttacaaggag gaaataattt gaacattata ataagtctaa tgggtggatt
     5281 aggtctgttc ttatatggta tgaaccttat gggagaaggt cttcaaaaat ctgctgggac
     5341 aaagctaaaa aagataataa aactacttac tagtaaccta tttatgggag ttttggtagg
     5401 tacaggagtt acagcagtaa tacaaagttc aagtgctact actgtaatgg ttgttggttt
     5461 cgtaaatgca ggaataatga ctttaaaaca ggcaatagga gttataatgg gtgctaatat
     5521 agggactact gttacagccc aattggtatc tttcgactta actggtatgg ccccagtagc
     5581 attaggtgta ggtattatac tttatttatt tggaaataag cctagaataa aaaatatagc
     5641 cgaaatactt ataggttttg gtatattatt tacaggtatg gattttatga agatggcagt
     5701 ggagccacta agagactatc aaggatttac tgacttactt gttacatttg gtagatatcc
     5761 actacttgga ttattattgg gatttgggat tacagcaata atacaaagtt caagtgcatc
     5821 tatgggtatg ttggttgcac tggcagcaga aggtctagtg ccactatcag cagcactgcc
     5881 aattctttat ggccaaaata ttggtacatg tgtaacttca ctgttatcaa gtattggtgc
     5941 taacaaaaat gcacgaagag cagctatgat gcatctaatc ttcaatgttt taggaacggt
     6001 gatattctta atattcttga ataaaccagt agtaagcatg gttacaagtt gggatccaag
     6061 caatgttgca agacaaatag ccaatacaca tacattgttt aatataatat ctgtattgat
     6121 acttttacca tttacaagtc ttattataaa actagctata aagcttgttc ctgatagagc
     6181 aggtgatata gatgaagatg aaactaaaac tattaaatat atagatgata gaatgataga
     6241 aactccttct atagctcttg caaatacgat aaaagaagca cttcgtatgg gtgagaaggc
     6301 gaaggaaagc ctaaatgcat ctatggaagc tttagtagaa cattcaactg aaaaaataga
     6361 taagacatat agacgagaga gattaatcaa tgatttacag aaagctattt taaattattt
     6421 acttaaactt tcaaaagcag ctttagatga tgattcaaga gaagttgtgg atactttgtt
     6481 taatacagtc aatgatatag aaagaattgg tgaccacgct aaaaatatag ctgaattatc
     6541 acaagttgca atagattcaa atatttattt ctcagaagaa ggacaatctg aacttgatgt
     6601 tatgtataat agagttgttt cagcatatac ttatgcatta gaatcaatga ggagcgataa
     6661 tgttgattta gcttgcaagg ttataaaaat tgaagaacaa gttgatataa tggagaaatc
     6721 ttgtagagct aatcacatgt atagattgaa taataatcta tgtagtatag aaaatggagt
     6781 tatttattta gatgtaataa gtaatttaga gagaatatct gaccatgctg tcaatatagc
     6841 acaacaagtt atagcgaaga gattaggaaa tgattaaaaa taattaattt aaaataatat
     6901 aaaatttaaa atagaggata aataaaagag aaactttaaa tgatacgttt agagtttctt
     6961 tttttgtaaa tttatttgac taaaattttt aaatttatac atagttatag tatttagaag
     7021 aatcgatttc ctgataataa atgatgagat atgtatgatt ttgtggcaaa cttttaaaaa
     7081 aaacacctat attttgtgtt ataatctctt taaaacgaat atgctgaaaa gagggattta
     7141 aatgggaaaa ataaattttg attatagtaa agctacagag tttttttgtc aaaacgaaat
     7201 agatgtcatg caaccatatg tagatgttgc gcacgacatg ttacataata aaactggttt
     7261 aggaaatact tttttaggat ggatagacct tcctaaaaat tatgataaag aagagtttga
     7321 cagaataaaa aaatctgctg ataagataaa atcagactca gatgttcttt tggtaatagg
     7381 tataggaggc tcttatttag gttcgagagc tgctatagat atggtaagtc attcttttag
     7441 gaatggactt aaaaaagagc aaagaaaggc tccagaagta tattttgtag ggcataatat
     7501 aagctcaaca tatattatgg atttattaga tataattgaa ggaaaggata tttctgtaaa
     7561 tgtaatatct aaatcaggaa ctactacaga accagctctg gcttttagaa tatttaaaga
     7621 ttacttagag aaaaagtatg gtaaggaaga agcaagaaag agaatttatg caacaacaga
     7681 tgcaagtaaa ggtgcactta gacagttagc tacagaagaa ggatatgaga cttttgtaat
     7741 accagatgat gtaggtggtc gtttttctgt attgacagca gttggattac ttcctattgc
     7801 tgctgctgga cttgatattg atgctatgat gaaaggcgca aatgatgcta gagaagcatt
     7861 tcaaaatcct gacttaaaaa gtaatgatag ttatagatat gctgttgcta gaacaatttt
     7921 acatagaaaa ggaaaagatg tagagttatt agtgaactat gaacctcaac tacattatgt
     7981 aagtgagtgg tggaaacagc tttatggaga aagtgaagga aaagaaaata aaggtttatt
     8041 ccctgcttct gtagatttct caacagattt acattctatg ggtcaataca tacaagatgg
     8101 aaaaaggctt ttatttgaga cagtacttaa tgttgaaaac tgtaagagaa atataactat
     8161 aagttcagag gaagtagact tagatggttt aaattattta gcaggtaaga ctgtagattt
     8221 tgtaaatcat aaagcttttg aaggaactct attggctcat acagatggaa aagtacctaa
     8281 tttagtaata aatatacctc aactagatga gtataatttt ggatatttag tttatttctt
     8341 tgagaaggct tgtggaataa gtggatattt attgggagtt aatccatttg accaaccagg
     8401 agtagaagct tacaagaaaa atatgtttgc tttactaggc aaaccaggtt atgaaaaaga
     8461 aaaggaagag ctagaaaaaa gacttaaata attttaaata gttaaggttt aattaagatt
     8521 aaaataatat aatgaaatca tcaaaaagga gtttactcaa aatagatgat ttcatttttt
     8581 ttatgaaaaa ttgggaaaaa tatattttga taatttatat tatattaaga tagggagtgg
     8641 tatgagatgt caagaagaaa gaaagggata agtttagtaa tattagttgc tataataagt
     8701 tcaatactta gtagttttct aacaataatt ttagttaagg acaatttagt aagcaaatct
     8761 acaggaagtt ctacgccgat agttgtaaat gatgatggta agagtcaaaa tatttatcaa
     8821 gcagttgcag aaaaagctac gccatctgtt gtaggtatta caacaactag tgttgatact
     8881 agtaatatgt ttgcaatacc aactgaaaca caaggtgtag gaactggaat catagttgat
     8941 tcaaatggat atatacttac taattctcat gttatatcag atggtcaagc tacaagtgta
     9001 aatgtattat tcaatgatgg ttcaacaact tcaggtaaag tagtatggtt tgaccaacaa
     9061 cttgatttag ctatagttaa ggttgataaa actggactaa caccagcaga atttgctgat
     9121 agtgacaaag taaaagttgg agatatatca atagcaatag gtaatcctct tggattagat
     9181 tttcaaaaaa cagttactca agggataata agtggattag atagaactat acaaacagaa
     9241 aaaactaata tgactggttt attacaaact gatgcaagta taaatgcagg aaatagtgga
     9301 ggaccattgt taaatcaaaa aggtcaagta attggtataa acacagcaaa agcttctcaa
     9361 gcagaaggat taggatttgc aataccaatc aatacagcta agagtatagt tgaagaagta
     9421 atcaaaaatg gaaaatatga aaaagtaact ttaggcataa aaggtacaga tgtatcaaat
     9481 tatgaagcag caacaggtac aaaattaagt actgataaag gtgtttatgt tgcagaagta
     9541 atatctggtt catcagcaga aaaagctgga gtaaaggtag gggatattat aactaaagta
     9601 ggagatacag atataacagg tatgaatgat ttaaataaaa agttgtatac tttctcaaaa
     9661 ggtgctagta caaaaataac agtaaataga ggcggaaaag cagtaacaat aaatgtgaat
     9721 ttctaaatat gaccaaaaag atagagacta catggtaaag tgtagtctct atttttattt
     9781 aatttttata gtatatacat ctaaattaat taaaatgatg tattgtttat agtttattgc
     9841 tatattttct tataaaaata aatttaataa atatttaaat ttaatttaca aaaacaatat
     9901 aaatatcata ataaaataaa attttttaat attactaaaa atatatagac aaaataataa
     9961 caaatatagt attatgtaat tgtagaaatg cttttcatag gtatattcta tgaagatgaa
    10021 ttgcataaaa atgaaaaaat ggaatggata ttatttaggg gtgaaaaatc atgaatccat
    10081 tagttataaa cttacaaaaa tgtagcatac atgatggacc agggataaga agtacagtat
    10141 tttttaaagg gtgtccactt gaatgtgttt ggtgtcataa tccagagagt caaacatata
    10201 caaaacaagt tttgtataat gaagaaagat gttcaaaatg tgaagcatgt ataaatatat
    10261 gccctcataa ggcaatttac aaaggtgaaa caaaaatatg cttagaccaa gataagtgtg
    10321 agttttgtga aacttgctta gactattgtg taaacaatgc aagagagatt gttggtcaag
    10381 agtattctgt aagagatttg gttaaagaga tagagaagga tagaattttc tatgaagaat
    10441 caggtggtgg agtaactcta tcaggtggag aagtaatggc tcaagatatg gacttcattt
    10501 gtggagtaat aaacatgtgc aaatcaaagg gaatccatgt agcaattgat acatgtggct
    10561 atgcaaagtc agaaaattat gaaagagttg ctaaatgtgc agatttgttt ttatatgata
    10621 ttaagcttat tgatgaagat aagcacataa aatttacagg aaaatcaaat gacttaatac
    10681 tgaaaaatgt taagatttta agtgaattag gggctaacat aaatataaga ataccattaa
    10741 ttgtaggagt aaatgtagat gatgaaaatt tagaggttaa aaaaatgata gagtttttaa
    10801 agcctttgaa tatacaagca gtaagtcttc ttccatatca taatattggt aaacacaagt
    10861 atgataaaat ttataaaaag tatgaaggag aagaactaca aagaccatca gaagaaaaat
    10921 tagaggaaat aaaaagactg tttgaagcaa gtaatttcaa tactaagatt ggagggtaat
    10981 aaaatggcaa gaggaacttt tgagagaact aaaaaattaa gagaagaaag tattaatgca
    11041 gaaccacaca tatctattga aagagcagta cttatgacag aagcttataa aaaatatgag
    11101 ggaagtgtag agattcctgt acttcgtgct ttatcattta agcattatat tgagaataga
    11161 actcttagca taaatgatgg agaattaata gtaggtgaaa aaggtgattc tcctaatgga
    11221 gcaccaacat atccagaaat ttgttgtcat acaatggaag atttagaagt aatgcacaat
    11281 agagatataa taaattttag cgtatcagaa gaagctagaa aaatacataa agaagaaata
    11341 attccttttt ggaaaaagag acaaacaaga gataagataa taaatgcaat gacacctgag
    11401 tggttagcag catatgaagc aggtatgttt acagagttta tggaacaaag agccccagga
    11461 catacagttt gtggagatac aatatataaa aaaggatttt tagatttaaa gaaagacata
    11521 gaagcaagat taaaagagct agattttctt aatgatttag atgcatataa taaaaaagca
    11581 gatttagaag ctatggcaat agcttgtgat gcaatggtta tattaggtaa aagatatgct
    11641 gagaaagcaa gacaaatggc agaagaagaa acagatgaag ctaagaaaca agatttatta
    11701 ctaattgctg aaacttgtga tgttgtacca gctcacaaac cagaaactta tcatcaagct
    11761 atacaaatgt attggtttgt tcatataggg gttactactg aacttaatat atgggatgct
    11821 tttactccag gaagacttga ccaacatcta aatcctttct atgaaagaga tgtagaaaat
    11881 ggaatactag atagagatag agcacaagaa ttacttgaat gtttatgggt taaatttaac
    11941 aatcagccag caccaccaaa agttggtata acattaaaag aaagtagcac atatacagat
    12001 tttgcaaata taaacactgg tggaataaat ccagatggtc aagatggtgt taatgaagtt
    12061 agttatataa tacttgatgt tatggatgaa atgaaattga tacaacctag ttcaaatgtt
    12121 caaataagta aaaagactcc tcaaaaattc ttaaagagag cttgtgaaat atcaagaaaa
    12181 ggatggggtc aaccagcatt ttataatact gaagcaatag ttcaagagct tatggaagct
    12241 ggaaaaacta tagaagatgc aagacttggt ggaaccagtg gttgtgttga aactggatgt
    12301 tttggtaaag aagcatatgt tctaactgga tatatgaaca ttccaaaaat acttgaatta
    12361 acattaaata atggatatga cccaattagt aaaaaacaaa taggtattga aactggagac
    12421 cctagaaatt tccaatctta tgaggaacta tttgaagcat ttaaaaagca attacattat
    12481 atgattgaca taaaaataga aggaaatgct gtgatagaaa atatatgtgc aaaacacatg
    12541 ccttgtccac ttatgtctac aatagttgat gattgtatag aaaaaggcaa ggattaccaa
    12601 agaggtggag caagatacaa cactagatat atacaaggtg ttggtatagg aactataaca
    12661 gatagtttaa cagcaataaa atataatgta tttgataaga aaaaattcga tatggataca
    12721 ttgcttaaag cacttgatgc taattttgaa ggatatgaag ctatacttaa tttagtttca
    12781 aataagactc ctaaatatgg aaatgatgat gattatgctg atgaaataat gcaagagata
    12841 ttcaatgcat attacaatga ggtaactggt agaccaactg tttgtggtgg agaatacaga
    12901 gtagatatgt taccaacaac ttgtcatata tactttggag aaattatggg agcaagtcca
    12961 aatggtagac tttgtgcaaa accagtttca gagggaattt cacctgaaaa aggtggagat
    13021 actaatggac ctacagcagt tataaaatct tgtgctaaga tggaccacat aaaaactggt
    13081 ggaacattat taaatcaaag atttgcacca tcagtagttc aaggagaaaa agggttagat
    13141 aatatggcta atctagtaag agcatacttt aatatggatg gtcatcatat acaatttaat
    13201 gtatttgata aaaatgtact gttagaggct caaaagaatc ctcaggatta taaagactta
    13261 atagttagag ttgcaggata tagtgaccat ttcaataatt taagtagaac actacaagat
    13321 gagataatag gaagaactga gcaaacattc taggtttgct tgtaaataaa acttcttact
    13381 atataaaatc gtaactgata taataaagta taaatggttt gattccattt ttaaaatttt
    13441 agattaatta tgagctaact ttctaaatag gaagttagct cgttaagttt aatgaaaaaa
    13501 tcgttaaatt tatatttagt aaatcataca catattagta agtaatacat acaaaagaat
    13561 aatttattat agttataata aggttatatt ttataaaaat aagataattt taagcagtta
    13621 aaataaagtc aatttagcta ctttaaaata aaactaatag aaaaaaggag atttgatatg
    13681 aaaactttag gatttattgg ttcagggaat atgggaagtg caatgatagg tggcatagta
    13741 cagtcaggat tagtaaaggc agaagatata actgtatcag atttaagcca agttgcctta
    13801 gataaagtaa aagaagaatt tggagtaaat actacaactg attcaaaggt agctgttaca
    13861 aattctgatg tggtaatagt agcacttaaa cctaatatat gcgaaaaggc tttaactcca
    13921 cttaaagaat taatagatgc aaataaaata atagtatcta tagcagcagg taaaactata
    13981 gaaagtctgg aaagttttat aggttcagat aaaaaaatag taagagtaat gcctaatact
    14041 ccagcccttg ttggcgaagg aatgtcagct ctttgtaaaa atagtaatgt aacagatgaa
    14101 gagttaaata tgattaaggc tctgtttgaa tcttttggtg aggcagaaat agtatcagaa
    14161 tatttaatgg atacagttac aggtattagt ggttcttctc ctgcatatgt atttatgttt
    14221 atagaagcta tggcagatgc agcagtatta gctggaatgc caagacaaca agcttataaa
    14281 tttgcatctc aagcagtaat ggggtcagct aagatggttc ttgaaactgg aaaacatcca
    14341 ggtgaattaa aagatatggt ttgttctcca gcaggaacta ctatagaagc tgttaaggta
    14401 ttagaagaag aaggctttag agcagcagtt ataaaatcta ttgttgcttg tatagataag
    14461 tctaaagata tgagtaaata acagatgtaa ttaagtttac tatatggttt cttgaattgt
    14521 ttttttagtg cttatttata tctatacata aatgtatttg gtataagtaa aataagagta
    14581 atttactata aaaaggaatt taatgattga gtgagaattt attacttaaa tattaataat
    14641 taaatagata tatttttaac tatatttgag atatatcatt gtgaaaaaat aaaatttata
    14701 agtattattg tgaggttata agtagattta tttaaaaata aatttattta tagccttttt
    14761 aa
//
LOCUS       DAEPKC010000099        14690 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.099, whole genome shotgun sequence.
ACCESSION   DAEPKC010000099 DAEPKC010000000
VERSION     DAEPKC010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14690)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14690)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14690
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.099"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            164..355
                     /locus_tag="KR294_003039"
     CDS             164..355
                     /locus_tag="KR294_003039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241098.1"
                     /translation="MERLMELIERKFLKDVELLELEDIENVIECKMTQPYNAHYNEYL
                     VKVKNGDEVEEYFVYLKHR"
     gene            complement(444..1256)
                     /locus_tag="KR294_003040"
     CDS             complement(444..1256)
                     /locus_tag="KR294_003040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mrp/NBP35 family ATP-binding protein"
                     /protein_id="HBH0241099.1"
                     /translation="MADCNSCPSKGNCNSQSNCSIENNPNNKFGKIIGVMSGKGGVGK
                     STVTALLANKLNKMGYKVGILDSDITGPSIPRLMGVKNVKAYSDGSYIYPVENSNNIK
                     VMSINLMIDDENEPVVWRGPLLGGVVKQFYTDVLWEELDYLLIDMPPGTGDVALTVMQ
                     SIPISGIVMVSVPQDLVSMIVSKAVNMAKKMNINVLGVIENMSYIQCPDCSKKIKLFE
                     GESTEKFLDDLDLELLGELPMTKEIIDITHNGVTEISDDLDSILTNVVEKIK"
     gene            1678..2829
                     /locus_tag="KR294_003041"
     CDS             1678..2829
                     /locus_tag="KR294_003041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004452985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH0241100.1"
                     /translation="MELRPRSAKLEEFDKVIELINYVFRISRNHKPTMMEEFPLLLSK
                     NNIENMIIISEDDKVVSDVNYLIQDVSIQGNRLKVAAIGGVCTHPDYEKRGYSSKILD
                     KVEEKMFYDGVDIVIISGTRSLYSRRNCSLVKSFYKYTIKPEDVKIAYEIVEFDETNF
                     EKDNDLDKMIELYNQNSTRFIRTRDEFQKLLHAATIAWGPIGYKKVFIKENNNIIGYL
                     IIRTIKKEDSTVGEVAEIGLNSVNVENILKYVANKFGLESLNYKVHVKNLKDQLKCNG
                     TKSLDYQQGTMKIINFTKLCDSLRSYFSQYVDFELLKYMEFKQVENKYIIKYKEEELV
                     IENLDKLNKLFFEKNEEQYNEFKHLKNIYEFATKAFPVDFPWTANLNYQ"
     gene            2947..3585
                     /locus_tag="KR294_003042"
     CDS             2947..3585
                     /locus_tag="KR294_003042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423639.1"
                     /note="Presence of a B(12) (cobalamin)-binding domain
                     implies dependence on cobalamin itself, in one of its
                     several forms, or in some unusual lineages, dependence on
                     a cobalamin-like analog; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin-dependent protein"
                     /protein_id="HBH0241101.1"
                     /translation="MDILDDIAECILNMGVDNIENLVKIAIDKNIDVEDIYEYGLNKG
                     MIGALDKFENKEYYLSEVIVCTDALNKGINLLKGTGKVKKKSKGVILMSVVEGDTHEI
                     GKNIVKVMVEATGYKVIDLGVNRKSEDIIEEAIKNNVDIIGLSSMMTTTMENMKSVID
                     ELNMIEIDKRPKVIIGGGPVSMEFAEEIGADGYSSNAPKAVKLINKLIGGEV"
     gene            3586..4608
                     /locus_tag="KR294_003043"
     CDS             3586..4608
                     /locus_tag="KR294_003043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase"
                     /protein_id="HBH0241102.1"
                     /translation="MFSDMTLLQYINSEDRGFFLPDMGTNGLFLINKKAYEVYDSVDL
                     QLELAKTMDKYFESDFIYSFCDGITFCETLGLDTLRPDYDFPSVLTHTITDRDKLRKL
                     DVPDPYTSGRMPLNIESLSVISKSIKKPLYESIQGPFTLAGQLAGATQLLRCIITDKK
                     FVEELLEFTTELVRRYAVAANKAGAKYISIAEPTSVTLSKDRFDEFIVKNLNKIYNEL
                     DCWKGMHICGDTRELLDNMLSCNIDAVSLDQILDYEEIAPMIPRDIVLIGNLDPIKLL
                     GRSKPDKIRRETLKLLKKMRRYDNFLCDFGCNCLNTTPVENLQAAIKAGRISYKELDR
                     IDIDEL"
     gene            4598..5218
                     /locus_tag="KR294_003044"
     CDS             4598..5218
                     /locus_tag="KR294_003044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241103.1"
                     /translation="MNYNSNKNKYLLKDINLDDIFIDKNIVLKFLGYGNRKAPDTISK
                     IVEREIRNINDILDIKIYISEVDINKTPKECKKAFAVLYTIGDKIDFKMNDYMENCNM
                     MAGLALDKVGIVCLDCINEKIKMYLKGKYDSLKISHEIYPGDKDFEVERQKDIYNYVK
                     NKYNSIEIEINDYHQLSPIKSVAMLILMGDEENLESRCSKCPRKCF"
     gene            complement(5342..6028)
                     /locus_tag="KR294_003045"
     CDS             complement(5342..6028)
                     /locus_tag="KR294_003045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HBH0241104.1"
                     /translation="MKTYKFIFFDADDTLFDFKKSESHAFKKLLSEFDLEFNFENYIE
                     SYRNISDKLWLDLEKNIITLNELKLLRFELFANKISLDVDSETLSKMYLNFLGECTFL
                     IPGAIDILQYLKKKYTIVIITNGISAVQKKRLENSKIKEYIDGMVVSEELKISKPNPE
                     IFKYALKKFNCHDKSSALIIGDSLTSDILGGINSGIDTCWLNSNNSINYTNHIPTYEI
                     NTLIELKKLL"
     gene            complement(6042..6587)
                     /locus_tag="KR294_003046"
     CDS             complement(6042..6587)
                     /locus_tag="KR294_003046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH0241105.1"
                     /translation="MNDLNLGEKIAEVRKKQNLSIRDLAKLADVTPSLLSQIERGLAN
                     PSVNSLKSIASSLNVPLFTFFVSEVDKKNLIVRHDNRKKVILPGSKEVIYEILIPDSS
                     GNLEFAIMDLAPNTSSCVDRITHNGDEIAYVLEGEVKLFMDDDEFTLSKGDSVKVPLG
                     TKHKWQNDSNSESKVIFAVIL"
     gene            6815..8062
                     /locus_tag="KR294_003047"
     CDS             6815..8062
                     /locus_tag="KR294_003047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HBH0241106.1"
                     /translation="MQITTFGAIFGLLIAIILIIKKFQAVYSLMLGAFIGGLVGGANI
                     TQTVDFMANGAMNISPSILRALASGVLAGSLIKTGAVDKISEQIVKIFGEKRALFSIA
                     ISTMVLAGVGVNLDVSIITVAPIGLYIGRKLNYSKLSILLAMLGGGKAGNIISPNPNT
                     IAVADNFSVNLSSVMMANIIPAIIGVVITVILASILINKGNKVQSYEILEQREDLPSL
                     FKSLCGPIIAIFLLFLGNVSPIVIDPMIALPIGGIVTLIVTGNLNNSREYLAFGLSKM
                     QGVCILLLGTGTIAGIIQMSELQQSTIGALQFLNMPQFLLAPVSGILMSLATASSTAG
                     ATIASSTFHDAIINGGLSPISGASIVNAGSSVFEQLPHGSLFHTSAGSINMDIGERFK
                     LIPYEALIGIVMTIISTSIQLVL"
     gene            8149..10143
                     /locus_tag="KR294_003048"
     CDS             8149..10143
                     /locus_tag="KR294_003048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HBH0241107.1"
                     /translation="MNKKKIVIIGIIYSFLVVFSLTNMYVNMEYNLNVFEYIKKSLPF
                     TEEEKKWLEKHKNLIYSSDQSSPPLRYKGKEDGQYKGIIVDLINSLSIQIGRDFYFKP
                     NNWWKESFVNSIDDSIKFFDLIPSKERANKFIFTDPIYTLSANILKDKKSQDINSYMD
                     LKGKTVAIPEGDYSINFLKQKIQDINILLTPDIKTGVNHLMSGKVDAVVGDEPVLRYY
                     INNYGLSNKYSVLSNPIYTKKAVLAVPKQYEELVSILNKGIFKLQKNGVYKDLKKKWY
                     STYNEVDDILYERGIVPSIYLFIGIILISIYVFYSYTYLLKIEIKRKTEQVIENKKTL
                     EATFNSITDIIMLVDENNNIVESNKVLYDFMGEMSYKIADLISMIKGVIENTFSENTN
                     KTSEIEIHNKILKINTFPVEYKKNNTEYIVVLIKDITNDKIVEAKLLRENKMISIGQL
                     ASGVAHEIRNPLGIIRNNCYLLKDNVTMEEVNDCVKSIESNVDRASNIITNLLNFARI
                     SDDNLEHINIRNFIENIVKLQYKMLQLKNVEIKIDCEHNLVCYINGESLKHVFINLIS
                     NSIDAIHQDGKIIIYCYEKNYCLFIDFKDNGEGIKEDALKDIFNPFYTTKPIGEGTGL
                     GLYITYNEIKKNNGDISVESKLGVGTCFHIKIPLNKEVTI"
     gene            10143..11465
                     /locus_tag="KR294_003049"
     CDS             10143..11465
                     /locus_tag="KR294_003049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent Fis family transcriptional
                     regulator"
                     /protein_id="HBH0241108.1"
                     /translation="MKILLVDDELEYGVVMKKILQKKGYLVDIALSGEEAINIIKKDK
                     NYDLVLSDVMMKNMDGVQLLDRIKSINRDIEVILVTGYGSIENAVDAMKRGALSYFIK
                     SNPIENLLEEVEKVKASKISVSVQKNNLEFTLESKNRDFNNIIKIAKKAACKDVNILI
                     LGESGVGKDILARYIHSISPRKNEIFVPVNCCSFSENLLESELFGHEKGSFTGAVDSR
                     KGRFELSNKGTLFLDEIGDIPLNVQVKLLRTLEDKSIERIGSNKSIKVDFRLICAMNK
                     EPKVEISNGNIREDFFYRISTITITIPPLRKRREDLTTLIEFFLNKYQIEHDKKIHSI
                     DKEVKDFLLNYNYPGNIRELKNIINRLVVLSEEGNLSKDNLNLISNNVYIDDKISIRP
                     LREIRKEFECEYIEKVLSLCGNNISNTAKKLEISRRQLTNKISEYNIK"
     gene            11744..13030
                     /locus_tag="KR294_003050"
     CDS             11744..13030
                     /locus_tag="KR294_003050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006807454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase component B
                     subunit"
                     /protein_id="HBH0241109.1"
                     /translation="MKLELGNIFIKNVEFGEKTEVKDGVLYISSEEIEKIVLEDERIV
                     SVNVELARPGESIRIAPVKDVIEPRVKIGDESKIFPGIINKVKTVGSGRTHVLLGACV
                     VTCGNIVGFQEGVIDMSGPTAKYTPFSKTNNICIVIKAKDGIDTHDYEEAARIAGLKI
                     GAYVGEAGREVEPDEVIVYETKPLLKQVKEYPDLPTVAYVHMLQSQGLLHDTYYYGVD
                     AKQIVPTFMYPTEIMDGAIISGNCVAPCDKVTTFHHLNNPVIHDLYKRHGKDLNFIGV
                     ILTNENVFLVDKERSSDMVAKLIEFLGVDGVLVTEEGYGNPDTDLMMNCRKCSEVGAN
                     VVLITDEFPGKDGKSQSIADATKEADAVVSCGQGNLVVHFPAMEKIIGTLDYVEMMIG
                     GYKGCLNEDGSMDAELQIIIASTIANGYNHLTARYY"
     gene            13116..14423
                     /gene="grdB"
                     /locus_tag="KR294_003051"
     CDS             13116..14423
                     /gene="grdB"
                     /locus_tag="KR294_003051"
                     /EC_number="1.21.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012158817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:14163..14165,aa:Sec)
                     /transl_table=11
                     /product="glycine reductase complex selenoprotein B"
                     /protein_id="HBH0241110.1"
                     /translation="MSKIRVVHYINNFFAGIGGEEKADIPPEKRAGVVGPGIAFQSQF
                     NDDAEIISTVICGDTYFGENIESATQELLKMIKEESPDLFIAGPAFNAGRYGVACGTI
                     CKAVEEELNIPVITGMYKENPGVDMFKLDLHIVSTGNSAASLRKVVPIMTKLGLKLVR
                     GEEIGPPEEEGYIMRGIRKNFFHELRGSERAIDMLVKKMKGESFETEYPMPEFDRVTP
                     MKPVKDLSKIKLALVTSGGIVPIDNPDKIESSSATKYGIYDLTDMDSMSNKEFTTIHG
                     GYDRAYVLENPNLVVPLDVVRELEKEGVIGELVDYFITTTGTGTSVGNSKRFGEEFSK
                     KLLEDDVDAVILTSTUGTCTRCGATMVKEIERAGIAVVHICTVVPISLTIGANRIVPA
                     VGIPYPLGNPMLGEEESKKIRKNIVLKALNALTEDIEEQTVFE"
BASE COUNT         5868 a         1540 c         2485 g         4797 t
ORIGIN      
        1 tttatcaagg catatttatt aaaaaatcaa tctctatttg ttaaaataat ttatgaatga
       61 tgttagaaac tgtaatatat tggatataat ataataaaca gataaactct gcattaagag
      121 gatatatagt ttatcttaat tataggggaa gtgaggatat attatggaaa gattaatgga
      181 actcatagaa agaaaatttt taaaggatgt agaactttta gaattagaag acatagaaaa
      241 tgtaatagaa tgcaaaatga cacagccata taatgctcat tataatgaat atttagtaaa
      301 agtaaaaaat ggagatgaag tagaagaata ttttgtgtat ttaaaacata gataaacata
      361 aaagaggttt atatttattt gtatgattat aaaataaata caagcctctt tttttgataa
      421 atataaaatt ataaaatttt tatttattta attttttcaa caacattagt caatattgaa
      481 tctaaatcat cactaatttc tgtaactcca ttatgagtaa tatctataat ttctttagtc
      541 ataggaagtt ctcctaaaag ctctaagtct aaatcatcta aaaacttttc agtagattct
      601 ccttcaaata acttgatttt tttagaacaa tcaggacatt ggatataact catattttca
      661 ataactccaa ggacatttat gttcattttt ttagccatat taacagcttt tgatacaatc
      721 atagatacca aatcttgagg tactgaaacc ataactattc cacttatagg aatagattgc
      781 ataactgtta aggcaacatc tccagtacca ggaggcatat ctattaataa atagtctaat
      841 tcttcccaaa gtacatcagt ataaaattgc tttacaaccc ctccaagtaa aggtcctctc
      901 caaacaacag gttcattttc atcatctatc ataaggttta tagacattac ttttatgtta
      961 tttgagtttt ctacagggta aatataagag ccatcagaat aagcttttac attttttaca
     1021 cccataagtc taggaatact tggtccagtt atatctgagt ctaatatacc aaccttatat
     1081 cccattttgt ttagcttatt agcaagtaaa gcagttacag ttgattttcc aactccaccc
     1141 ttcccactca taacaccaat tatttttcca aatttattgt tagggttatt ttcaatagaa
     1201 caatttgatt gactattaca atttcccttt gatggacatg aattacaatc tgccatatct
     1261 attacctcca aactttaata tttattagat tatttgtaac ctacatatac tattttagta
     1321 caattgaacc ataaagtcat tatttaaaag caacttagaa gattttctat tgatttattc
     1381 atagactata gcaaaaagaa tacaataaaa aaattataac attcttgaaa aagtgattat
     1441 ttcaatttag ttatagaact tagtcatata aatatataga aaatatttta atatattata
     1501 cataacgggt tattttataa gtttaactat aaattaggtt tatattttat aaaaatttgc
     1561 taaaaaaaac aattaaaaat tgtaaagaaa aaagatataa ttagaactgt agtaataaat
     1621 gttttattat agataataga gttttaagta tcttaaataa tatttggagg aatatgaatg
     1681 gaattaagac caagaagtgc aaaattagaa gaatttgata aagtaataga attaataaac
     1741 tatgtattta gaatatcaag aaatcataaa ccaactatga tggaagaatt tcctctttta
     1801 ctaagtaaaa ataatataga aaatatgatt ataatatcag aagatgataa agtggtttct
     1861 gatgtaaact atctaattca ggatgtatct attcaaggaa acagattgaa ggttgcagct
     1921 ataggtggag tatgtactca tccagattat gaaaagagag gctattcatc taagatattg
     1981 gataaagtag aagaaaaaat gttttatgat ggtgtagata ttgtaattat atcaggaaca
     2041 agaagtctat acagtagaag aaattgtagt ttggtaaaga gtttttataa atatacaata
     2101 aaacctgaag atgtaaaaat agcatatgaa atagttgaat ttgatgaaac taattttgaa
     2161 aaagataatg atttagataa aatgattgaa ctatataatc aaaatagtac tagatttata
     2221 agaacgagag atgagtttca aaaactattg catgcagcaa ctattgcctg gggaccaatt
     2281 ggttacaaga aggtatttat aaaggaaaat aataatataa taggatattt gataataaga
     2341 acaataaaaa aagaagattc tactgtagga gaagttgctg aaatagggtt aaactctgta
     2401 aatgttgaaa atatattgaa atatgttgca aataaatttg gattagaatc tttaaattat
     2461 aaagtacatg tgaaaaatct taaagaccag ttgaaatgta atgggacaaa atctttggat
     2521 tatcaacaag gaactatgaa aataataaat tttactaagt tgtgtgatag tttaagaagt
     2581 tattttagtc aatatgtaga ttttgaatta ctaaaataca tggaatttaa acaagttgaa
     2641 aataaatata ttattaaata caaagaagaa gaacttgtaa tagaaaattt ggataagctt
     2701 aataaactgt tttttgaaaa aaatgaggaa cagtacaatg aatttaaaca tctaaaaaat
     2761 atatatgaat ttgctacaaa ggcatttcct gtagattttc catggactgc aaatttaaat
     2821 tatcaatagt tttagatgat attaaataaa attgattgat acctagagtt agtccttgtt
     2881 aaataagaga aattattgga tattgaaaaa gcaattttgt aagtaattag aaaggatgag
     2941 tattatatgg acatacttga tgatatagca gaatgtatat taaatatggg tgtagataat
     3001 atagagaatt tagtaaaaat tgctatagat aaaaatattg atgtggaaga tatttatgaa
     3061 tatggtttaa acaaaggtat gataggagct ttagataagt ttgagaataa ggaatactat
     3121 ctttcagaag ttatagtatg cacagatgca ttaaataaag gtattaatct tttgaaggga
     3181 actggaaaag taaagaaaaa atcaaaggga gtaattctga tgtctgtagt agaaggagat
     3241 actcatgaga taggaaaaaa tattgtaaaa gtaatggtag aagccactgg atataaggtt
     3301 attgacttag gtgtaaatag aaaaagtgaa gatataatag aagaagctat aaaaaacaat
     3361 gtagatataa taggcttatc ttcaatgatg acaactacaa tggaaaatat gaaatcggtt
     3421 atagacgaac ttaatatgat tgagatagat aaaagaccaa aagtaataat tggtggagga
     3481 cctgtaagta tggagtttgc agaagaaata ggagcagatg gatacagttc aaatgctcca
     3541 aaagcagtta aattaataaa taaacttata ggaggtgaag tttaaatgtt ttcagatatg
     3601 actttacttc agtatataaa tagtgaagat agaggttttt ttctgcctga tatgggtaca
     3661 aatggattgt tcttaataaa taaaaaggca tatgaagtat atgatagtgt agatttgcaa
     3721 ttagaattag caaagactat ggacaagtat tttgaatcag attttatata ctcattctgt
     3781 gatgggatta cattttgtga aactctgggt ttagatacat taagaccaga ttatgatttt
     3841 ccaagtgtat tgacacatac tataactgac agagataaat taagaaaatt agatgttcca
     3901 gacccttata cgagtggacg tatgccactc aatatagaga gcttatcagt tatatcaaaa
     3961 agtattaaaa aaccactata tgaatcgata caaggtccat ttacacttgc aggtcaatta
     4021 gctggagcta ctcaactttt aagatgtata ataactgata aaaaatttgt agaagaatta
     4081 ttggaattta caactgaatt ggtaagaaga tatgctgtag ctgcaaataa agcaggagca
     4141 aaatatattt caatagcaga gccaacatca gtaaccctaa gtaaagatag atttgatgaa
     4201 tttatagtaa aaaatttaaa taaaatctac aatgaacttg attgttggaa aggtatgcat
     4261 atatgtggag acaccagaga attattagat aatatgctaa gttgtaatat agatgcagta
     4321 agtttagacc aaattttaga ctatgaagaa attgctccaa tgattcctag agatatagtt
     4381 ttgattggta atttagaccc aataaaactt cttggacgtt ctaagccaga taagattaga
     4441 agagagacac taaaattgtt aaagaagatg agaagatatg ataacttttt atgtgatttt
     4501 ggctgtaact gcttaaatac cactccagta gaaaatttac aagcagctat aaaggcagga
     4561 agaattagtt ataaagaatt agataggatt gatattgatg aattataata gtaataaaaa
     4621 taaatatctt ttaaaggata taaatttaga tgatattttt atagataaga atattgtgct
     4681 aaagtttttg gggtatggaa atagaaaagc tccagataca attagtaaaa tcgttgaaag
     4741 agaaataaga aatataaatg atattttaga tatcaagata tatataagtg aagttgatat
     4801 taataaaaca cctaaagaat gtaaaaaagc atttgctgta ctatatacaa taggggataa
     4861 aattgatttt aagatgaatg actatatgga aaattgcaat atgatggcag ggctggcatt
     4921 ggataaggta ggtatagtat gtttagattg tattaatgag aaaataaaaa tgtatttaaa
     4981 aggaaagtat gatagtctca aaatatcgca tgaaatatat ccaggagata aagattttga
     5041 agtagagaga caaaaggata tttataacta tgtaaaaaat aaatataata gtatagaaat
     5101 agaaattaat gattatcatc aactatcccc cataaaaagt gttgcaatgc ttattttaat
     5161 gggggatgaa gaaaatttag aatcaagatg tagtaagtgt cctagaaaat gcttttagtt
     5221 aattttcaag actaagattt gttttgtgta taaattgcaa taattttttt ggtcatttta
     5281 tgtataaact aaaaaaatta ttgcaaagta atattctatt taatttgaac agacttacaa
     5341 actatagtag tttctttaat tcaataagtg tatttatttc ataagttggt atatgattag
     5401 tataatttat actgttattg gaatttaacc aacaagtatc tattcctgaa tttattccac
     5461 ctaagatatc agaggttaag ctatccccaa ttattaaggc agaagattta tcatgacaat
     5521 taaacttttt gagagcgtat ttaaatattt caggatttgg ttttgatatt ttcaactctt
     5581 cagatacaac cattccatca atatattctt ttatttttga attttcaagt cttttctttt
     5641 gaactgcaga aattccattt gttattataa caatagtata ctttttttta agatattgta
     5701 atatatcgat tgcacctgga attaaaaatg tacattcacc taaaaaattt aagtacattt
     5761 tgctaagagt ttcagaatca acatccaaag atattttatt tgcaaaaagt tcaaatctaa
     5821 gtaatttaag ttcattcaaa gttataatat ttttttcaag gtcgagccaa agcttatcac
     5881 ttatatttct atatgactct atataattct caaaattaaa ttctaaatca aactcagata
     5941 gaagtttttt aaaagcatgt gattcacttt tcttaaaatc aaataaagta tcatctgcat
     6001 caaaaaatat aaatttatat gtcttcatgg tttttactcc tttacaagat gactgcaaaa
     6061 attactttac tttcactatt tgagtcattt tgccatttat gttttgttcc taaaggaact
     6121 tttacactat ctcctttgga caaagtaaat tcatcatcat ccataaaaag tttaacttct
     6181 ccctccaaaa catatgcaat ttcatctcca ttatgagtaa tcctatcaac acaagaagaa
     6241 gtgtttggag ctaaatccat aattgcaaat tctaaattac cactagagtc tggaattaaa
     6301 atctcatata taacttcttt gcttccaggt aaaataactt tttttctatt atcatgtctt
     6361 actatcaagt tttttttatc tacctcagat acaaaaaatg taaataaagg aacgtttaga
     6421 gaagaggcta tagattttaa tgaatttaca gatggattag caagacctcg ttctatttgg
     6481 ctcaataatg atggtgtaac atcagctagt tttgctaaat ctcgaatact taagttttgt
     6541 ttttttcgaa cttcagctat tttttcccct aaatttaaat cattcatata aatatcctct
     6601 ctttttaatt taaaaaatat taacttaaaa taatcaagta aaatgattat gtagtatgaa
     6661 attattataa catatagaat taggttttga aaaaactatg ttcaatataa ttaaataaat
     6721 taaaatataa ttgacaaagt ggatacagaa tacttaaaat atatttaaat aaaattaagc
     6781 aaaagatagt taatttatga taggagggga tattatgcaa ataacgactt ttggagctat
     6841 atttggttta ttaatagcaa ttattttaat tataaaaaaa tttcaagctg tatatagttt
     6901 aatgctagga gcatttattg gaggattagt tggaggagca aatataacac aaactgtaga
     6961 ttttatggca aatggagcta tgaatatatc accatcaatt cttagagctt tggcatcagg
     7021 tgtattagct ggaagtttaa taaaaacagg ggcagtagat aaaatatcag aacagattgt
     7081 aaaaatattt ggtgaaaaga gggctttatt ttcgattgcc atttcaacta tggtacttgc
     7141 tggagtaggc gtaaatttgg atgtatctat aataactgta gcacctatag gattatatat
     7201 aggtagaaaa ttaaattatt ctaaattgtc aatactatta gctatgttgg gagggggtaa
     7261 agcaggtaat ataatatcac caaatccaaa tactatagca gtagcagata atttttctgt
     7321 caatctctct agtgttatga tggcaaatat aattccagca attattggag ttgttattac
     7381 agttatttta gcaagtatat taataaataa aggaaataaa gtacaatcat atgaaatttt
     7441 agagcaaaga gaagatttac caagtttatt taaatcatta tgtggtccaa ttatagctat
     7501 atttctattg tttttaggaa atgtatctcc tatagttata gacccaatga tagcccttcc
     7561 aataggagga atcgtaactc taattgtcac aggaaacttg aacaattcaa gagaatattt
     7621 agcttttgga ttatctaaga tgcaaggggt atgcatatta ttacttggaa cagggactat
     7681 cgcaggaatt atacagatgt ctgaattaca acagagtaca ataggtgctt tacaattttt
     7741 aaatatgcca caatttttat tggcaccagt ttcgggtata cttatgtcat tagcaacagc
     7801 atcatcaaca gctggtgcta ctatagcatc atctactttt catgatgcta taataaatgg
     7861 tgggctatca ccgatttcag gtgcctcaat agtaaatgct gggtctagtg tattcgagca
     7921 attaccacat ggctcactat ttcatactag tgcaggtagt ataaacatgg atataggtga
     7981 aagatttaag ttaattccat atgaagcatt gataggaata gtaatgacta taatttcaac
     8041 atctattcaa ttagttttat aataaatata aatatttaat gaaaaaagta ggattttgtt
     8101 attaaatatt gaatttatta tagtaaaaaa gaagattgga gttttaaagt gaataaaaaa
     8161 aagattgtta ttatagggat tatttattca tttttagtag tattttcact tacaaatatg
     8221 tatgtaaata tggagtataa tctaaatgta tttgaatata ttaagaagtc acttccattt
     8281 acagaagaag aaaaaaagtg gttagaaaaa cacaagaatt tgatttacag ctctgaccaa
     8341 agttcacctc ctttgagata taaaggtaag gaagatggac agtataaggg aattattgtt
     8401 gatttaataa attctctgtc aattcaaatt ggtagagatt tttattttaa accaaataat
     8461 tggtggaaag aatctttcgt aaattcaata gatgatagta taaagttttt tgacttgatt
     8521 ccatcaaaag aaagggcaaa taaatttata tttactgacc caatatacac tttgagtgca
     8581 aatatattga aagataaaaa gtcccaagat ataaatagtt acatggattt aaaggggaaa
     8641 acagtagcaa ttccagaagg tgattattct ataaattttt taaagcaaaa aattcaagat
     8701 ataaacattt tgttgactcc agatataaag actggagtca accatttaat gtctggaaaa
     8761 gtagacgcag ttgttggtga tgaaccagta ttgcgatact atataaataa ttatggactt
     8821 tcaaataaat acagtgtttt aagtaatcct atatatacta aaaaagcagt tcttgctgta
     8881 cctaaacaat atgaagagct ggttagtatt ttaaataaag gcatttttaa acttcagaaa
     8941 aatggagtgt ataaagattt aaagaaaaaa tggtattcta cgtataatga agttgatgat
     9001 atattgtatg agcgaggaat tgtgcctagt atttatcttt ttataggtat aattttaata
     9061 tcaatttatg ttttttatag ctatacatat ttgttaaaga tagaaatcaa aaggaaaaca
     9121 gaacaggtaa tagaaaataa aaaaacttta gaggcaactt ttaatagtat tacagatata
     9181 ataatgcttg tagatgaaaa taacaatata gtagaatcga acaaagtact atatgacttt
     9241 atgggtgaaa tgagttataa gatagcagat ttgattagca tgataaaagg tgttattgaa
     9301 aataccttct ctgaaaatac taataaaact agtgaaatag aaatacacaa taaaatttta
     9361 aagataaaca cttttcctgt agagtataaa aaaaataata ctgagtatat agtagttctt
     9421 attaaagata taactaatga taaaatagta gaggcgaaat tacttagaga aaacaaaatg
     9481 atatctatag gacaattagc ttctggggta gcacatgaga taagaaatcc tttgggtata
     9541 ataagaaata attgctatct cttaaaagat aacgttacaa tggaagaagt aaatgattgt
     9601 gttaaatcaa tagaaagtaa tgtagatagg gcaagtaata taataaccaa cttgttaaat
     9661 ttcgcaagaa tatcagatga taatttagaa catataaata taagaaattt tattgaaaat
     9721 atagtgaaac ttcaatataa aatgttacag ttaaagaatg ttgaaataaa aattgactgt
     9781 gaacataatt tagtatgcta tataaatgga gaatcgttaa aacatgtatt tataaattta
     9841 atttctaatt caatagatgc aatacatcaa gatggaaaaa ttattatata ctgttatgaa
     9901 aaaaattatt gtttatttat agattttaaa gataatggtg aaggaataaa agaagatgcc
     9961 ctaaaggaca tatttaatcc cttctataca acaaaaccaa ttggtgaggg aactggttta
    10021 ggtttataca ttacttataa tgagattaaa aagaataatg gagatataag tgttgaaagt
    10081 aaattggggg ttggaacttg ttttcatata aaaattccat taaataaaga ggtgactata
    10141 taatgaaaat actattagtt gatgatgagc tagaatatgg agtggtaatg aaaaaaattc
    10201 tacaaaagaa gggctatctt gtagatatag cactaagtgg tgaagaagct ataaatataa
    10261 ttaaaaaaga taaaaattat gatttggttt tgtctgatgt tatgatgaaa aatatggatg
    10321 gagtacagct attagataga attaaatcta ttaatagaga tatagaggtt atattagtta
    10381 caggatatgg aagtattgaa aatgcagttg atgctatgaa aagaggagct ttatcttatt
    10441 ttataaaaag taatcccatt gaaaatttat tagaagaagt tgaaaaggta aaggcaagta
    10501 aaatatctgt ttctgtacaa aaaaataatc tggaatttac tttggaatct aaaaatagag
    10561 attttaataa tatcataaaa atagcaaaaa aagctgcttg taaagatgtt aatatattaa
    10621 tcttggggga atctggtgta ggaaaagata tattagctag atatatacat agcataagtc
    10681 caagaaagaa tgagatattt gtacctgtaa attgttgttc tttttcagaa aatctattgg
    10741 agtctgagtt gtttggtcat gaaaaaggtt cttttacagg agcagtagat agtagaaaag
    10801 gtagatttga actttcgaat aaaggaactc tatttttgga tgaaatagga gatatacctc
    10861 taaatgttca ggtaaaactt ttgaggacac ttgaggacaa atctatagag aggataggaa
    10921 gtaataaatc tattaaagtt gactttaggt taatttgtgc tatgaataaa gaaccaaaag
    10981 tggaaatatc aaatggaaat ataagagaag atttttttta tagaataagt acaataacaa
    11041 taactatacc accgctaaga aagagaagag aagacttaac tactcttata gaatttttct
    11101 taaataagta ccaaattgaa catgataaaa agatacactc gattgataag gaagtaaagg
    11161 attttttatt aaattacaat tatccaggaa atataagaga attaaaaaat ataataaata
    11221 gacttgtagt tttaagtgaa gaaggcaatt tatcaaaaga caatttaaat ttaatatcaa
    11281 ataatgtata catagatgat aaaataagta ttagaccttt aagagaaata agaaaagagt
    11341 ttgaatgtga gtatattgaa aaagttttat ctttgtgtgg aaataatatt tcaaatacag
    11401 ctaaaaaatt ggagattagt agaagacagt taaccaataa aatatcagag tataatatta
    11461 agtgagaaaa aaacttctca ttaagtgaga aaaaaatttc tcaaactgta ttaaaagata
    11521 aacagaaaaa atctgtttat ctttttttat tataatttta aaaattaata tttacaataa
    11581 ttattgctaa attcaatatt ggtgtaaatt aaaaatgaaa atttctatga cattaataca
    11641 tagaatatat attttaaata attggcatag aaaatgcttt atatattaat aaacgtaata
    11701 aatactttta attgcgatta aatatattaa gggggatttt catatgaagc tagagctagg
    11761 gaatatattt ataaaaaatg ttgaatttgg agaaaagaca gaagtaaaag atggagtact
    11821 atatattagt agcgaagaaa tagaaaagat agtattagaa gatgaaagga ttgtaagtgt
    11881 aaatgttgaa cttgcaagac ctggcgaatc aataagaata gctccagtta aagatgtaat
    11941 agagcctaga gttaaaattg gagatgaaag caaaatattt cctggaatta taaataaagt
    12001 gaagactgta ggaagtggaa gaacccatgt acttttagga gcttgtgttg taacttgtgg
    12061 aaatatagtt ggatttcaag aaggcgtaat tgatatgagt ggtcctactg ctaaatatac
    12121 acctttttca aaaacaaata atatatgtat tgttataaaa gcaaaggatg gtatagatac
    12181 tcatgattat gaagaagcag ctagaattgc aggattaaaa ataggtgcat atgtaggtga
    12241 ggcaggaaga gaagttgagc cagatgaagt cattgtatat gagacaaagc cattattaaa
    12301 acaagtaaaa gaatatccag acctgccaac agtagcatat gttcacatgt tacaatcaca
    12361 aggactttta catgacactt attactatgg ggtggatgct aaacagatag tgcctacatt
    12421 tatgtatcca actgaaataa tggatggagc tataatatct ggaaactgtg tagcaccatg
    12481 tgataaggtt acaacattcc atcatttaaa taatccagtt atacatgact tatataaaag
    12541 acatggaaaa gatttaaact ttataggagt tattttgact aatgagaacg tattcttagt
    12601 cgataaagag agaagctctg atatggtagc taaattaata gaatttttag gagttgatgg
    12661 agttctagtg acagaagaag gttatgggaa tccagatact gacctaatga tgaattgtag
    12721 aaaatgtagt gaagttggag caaatgtagt tttgataacg gatgaatttc ctggaaaaga
    12781 tggcaagagt caatctatag cagacgctac taaggaagca gatgcagttg tttcttgtgg
    12841 tcaaggaaat ctagtggttc atttcccagc aatggaaaaa attataggaa ctttagatta
    12901 tgttgaaatg atgataggtg ggtataaagg atgcttaaat gaagacggaa gcatggatgc
    12961 agagctacaa attataatag catcaactat agcaaatggc tataatcatt tgacagcaag
    13021 atattattaa ataagtattt gaatataaag ttctgttgat ataatcattg gtctaattga
    13081 tgtaacaact ataaagtgat ttggaggatt aagagatgag taaaatcaga gtggttcatt
    13141 atataaacaa tttctttgct ggtataggtg gagaggaaaa agcagatatt ccgccagaaa
    13201 aaagggctgg tgtagtagga cctggaatag catttcagag tcaatttaat gatgatgcag
    13261 agataatctc aactgtaatt tgcggagata cgtattttgg tgaaaatatt gagagtgcaa
    13321 ctcaagaact tttaaaaatg ataaaagaag aaagccctga tttatttatt gcaggcccag
    13381 catttaatgc aggtagatat ggagtagctt gtgggactat ttgtaaggca gttgaagaag
    13441 agttaaatat tcctgtaatt acaggcatgt ataaagaaaa tccaggtgta gatatgttta
    13501 aattagattt gcatatagtg tctacaggaa attcagcagc aagtcttaga aaggtagttc
    13561 caataatgac aaaactaggt cttaaattgg ttagaggtga ggaaatagga cctcctgaag
    13621 aggaaggata tataatgaga ggaataagaa aaaatttctt ccatgaactt agagggtctg
    13681 aaagagcaat tgatatgttg gttaaaaaga tgaaagggga aagctttgaa actgagtatc
    13741 caatgcctga atttgataga gttacaccta tgaaacctgt taaagattta tctaagataa
    13801 aacttgccct agtaacttct ggagggatag ttccaattga taatccagac aaaattgaat
    13861 cttcaagtgc tactaaatat ggaatttacg atttaacaga tatggattct atgtcaaata
    13921 aagaatttac aactatacat ggggggtatg acagagcata tgtccttgaa aatccaaatt
    13981 tagttgtacc actagatgta gttagagagc ttgaaaaaga aggtgtaatt ggagaattag
    14041 tagattattt tataactact acaggaacag gaacgagtgt tggcaattct aagagatttg
    14101 gagaagagtt ttctaaaaaa ttgttagaag atgatgtaga tgctgtaatt ttaacttcta
    14161 catgaggtac ttgtactcgt tgtggagcaa cgatggtaaa agagattgag agagctggta
    14221 tagcagttgt tcatatatgt acagtagtac caatatcact tacaatagga gctaatagaa
    14281 ttgttccagc agtagggata ccatatccac ttggaaatcc tatgttagga gaagaggaaa
    14341 gtaaaaaaat tagaaagaat atagttttaa aagctttaaa tgcactaaca gaagatatag
    14401 aagaacaaac agtatttgaa taataaaaat acaacacaac actgaaataa aaaaagatat
    14461 caaaaaataa ttttttaaaa ttattttacg atatcttttt tttattaggt aaattcgaaa
    14521 tttgcatttt ttaaaattaa atttataaaa gtgataaatt agtttattat aatattgata
    14581 cacaaattca aattagatat actatgaaaa gcgagattat tacattttgg aacaaatatt
    14641 caacatatta gatcatatta attgaacaga aaaaattaac tttatataat
//
LOCUS       DAEPKC010000100        14662 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.100, whole genome shotgun sequence.
ACCESSION   DAEPKC010000100 DAEPKC010000000
VERSION     DAEPKC010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14662)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14662)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14662
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.100"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(<1..356)
                     /locus_tag="KR294_003052"
     CDS             complement(<1..356)
                     /locus_tag="KR294_003052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241111.1"
                     /translation="MSKIECLFTIFPVLILMYATFYFMPYFVGKKHIYGVSIDQEHKN
                     YNYFIKLDKEFKKLLSLGFIIDFILVFILVFTFNKLELSYFIGIIGFLLYESILYIHT
                     HKKAKKLKSEIYSKLG"
     gene            complement(349..738)
                     /locus_tag="KR294_003053"
     CDS             complement(349..738)
                     /locus_tag="KR294_003053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH0241112.1"
                     /translation="MVLNLDFNSDKSIYVQIKEEITKAIASGELKINESLPSVRSMAE
                     NIGVNLHTVNKSYNELKEEGFLNIDRRKGAIVAQLPMKIDNTTRQKNKLDLELLVAKS
                     YLSGISKEEFLSLSSSLFDKYEVKYYE"
     gene            930..1376
                     /locus_tag="KR294_003054"
     CDS             930..1376
                     /locus_tag="KR294_003054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241113.1"
                     /translation="MLTYLMKRQMHKKDDGMSKPMMITGAVITGVGAYAVYKMVKSHK
                     SNSQMVNTNYYGNSDYDDYKYDEFDYDCDCRDTKQDYEYEELKKKVKEFNSRRINCEN
                     CPHVSQEEMMQYVNSVKDVKEEIDLHEDAKKDNIYKEDEYKKYEEE"
     gene            1640..2365
                     /locus_tag="KR294_003055"
     CDS             1640..2365
                     /locus_tag="KR294_003055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0241114.1"
                     /translation="MKRKEIVMLKLLIVEDDSTISFGIKYALEQEGFSIDISKDLSSG
                     KEMISSNEYSMILLDVTLPDGTGYELCQYIRGFSQVPIIFLTACDEEVNIVMGLDIGG
                     DDYITKPFRIRELISRIKAVLRRKGNTSEENKKILKFGDLSIYTLEARVYKNDKEIFL
                     TSVEYKLLLILIQNKNTVLSRTQILEKLWDVTYDFVNDNTLTVYIKRLREKIGDDLCE
                     PIYIETVRGIGYKWIGSENSVSI"
     gene            2352..3596
                     /locus_tag="KR294_003056"
     CDS             2352..3596
                     /locus_tag="KR294_003056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH0241115.1"
                     /translation="MFLYNPEVKKFLSKYVTLMFIVIIISIGFSIINVSLTKEMVVRN
                     NQAIIGTLSSKYPNLESQIVDIITQGKSMENIDYGQKILIKYNYDKSIRINSEPIISK
                     LVLETIKINIILVCIIFILIFVLVVRYFKSIYNDLSDMTKYVYYSSEGKPFDMKNKNQ
                     EGQIGLLKTELLKMTTILNEKVELLKREKIFLNNTISDISHQLKTPMTSLIMLNDLLY
                     NDVPYEVKIDFLNKIKNQLNRMDWLIKSMLKLSKVEAKVINFKKDKVKFSELIHRAML
                     SMKIPMEIKNQKLTIEGNDNVSYIGDIDWSVEALVNIIKNCVEHTPEFGNIIITYKEN
                     PLFSELIIKDEGEGIDKKDIPHVFKRFYRGRSSSKEDSVGIGLAMSKSIIESQNGDIY
                     VNSEKGQGTEFHIIFHKMYDSD"
     gene            3676..4353
                     /locus_tag="KR294_003057"
     CDS             3676..4353
                     /locus_tag="KR294_003057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003517588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0241116.1"
                     /translation="MEILRVENLTKSYGKNETKVDAIKNVSLSVEKGTFIAITGPSGS
                     GKSTLLHLLGGVDRPTSGKVYINDVDIYNLKTKDLAIFRRRNIGLIYQFYNLIPVLNV
                     KENILLPAELDNRDIDREYFDDLMKTLGLIDREKHLPNQLSGGQQQRTSIGRALINRP
                     SIILADEPTGNLDSKNSKEILELLKLSVKKYNQTLIMITHDKNMALQADRIISIEDGI
                     IKSDEVM"
     gene            4354..6915
                     /locus_tag="KR294_003058"
     CDS             4354..6915
                     /locus_tag="KR294_003058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0241117.1"
                     /translation="MNLYTLLTIRYLKQNKRRTIVTIIGIILSTALICGIGNIFESFM
                     DYQMRETIKNDGSFHVTFYDVNRKNVEYVTKSAEIEKHAFTKQLGYSKLENSENAILS
                     IKQYDKNAINGYKVSIKEGRFPAKEGEIVLSESIINLIDDKLKIGDKITLKVGDMFDS
                     SKKKIDSMTFHEGDYIANEKDRTFKVVGIIEKPGFERYNGIATAIAYFNPMNNYNDTI
                     NVSVAVRNPKDVYKISNKISKNIYSNKDKEAVSDMIKYNEHLLRLQGASKYSNINNSI
                     KSIIIAVTILVIICTIATVYNSFSISINERKKQFGILNSIGATSSQIKRLVFIEGIII
                     SLIGIPIGLISGTVAIDLLFKIINKYFTESVVTKMSLQIVYNPIITIVSIIIVLLTIF
                     ISILLPAISASNISHLNVIKNTGEYKVGKIKSSRLIKMIFKTEGVLAYKNIRRNRKKF
                     IITLFSLMVSIIIFISFSGFTLLLLRGEEIRNSQRKYDLYLTAKNTARSVEDTISELE
                     DIDGIKNFELATGQYVSIRVSENKINKSKEDLIRKYYQKYKIGDSYEYDFSNNELIFP
                     GDFAVKNKINNLVQGSFNKERAIEENGVILVRKSAFEENGKKGVVELTNYKVGDTVNC
                     EYLDENALSKKVKVKILAITDEERLGLGYQNMGLQFITYDEVAKNLNLKLSKSLIFID
                     SGGSIKTKKEIEALANKNNFNFYDESASNESEKQDLKVIKIFVYGFIVVISLVSVTNI
                     LNTVSTSINLRKRELAVIQSIGVTPKGFRKMIYLESFIYGILSLLFGIPISIGIILIM
                     NKLISGVIEFSPIIPWTAIVICIVSVFIITFIAGYIPMSKLNKENIIDNIRRESI"
     gene            7106..8380
                     /locus_tag="KR294_003059"
     CDS             7106..8380
                     /locus_tag="KR294_003059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HBH0241118.1"
                     /translation="MITISHITAKNMYKSLEERINKFPQGAPPSDTLYKILNVLYTEQ
                     EAKLVAQLPIKPFRVKTAAKIWSVSESEAYRVLDKLASKALILDIEDNKGKKYIMPPP
                     MAGFFEFAMMRTRHDIDQKLLAELYYQYMNVEEDFIKDLFYSTETKLGRVYVQEEVLT
                     NDNEVSILDYERATHIIDESTHIGISMCYCRHRMQHVGKACDAPMDICMTFDNVANSL
                     INNKFARRVDKIECKELLHQAYEHNLVQCGENVRKGVTFICNCCGCCCEAMVAAKRFG
                     NLHPVQTTSFIPNINHENCVKCGKCITACPIDAISKVKEDGKEYIKIDEDRCLGCGVC
                     VRNCHKNSIMLLKRDEKIITPANSVHRAVLMAIEKGQLQNLIFDNNALASHRAMGAIL
                     SAILKLEPAKKILASKQLKSVYLDKLLSMNDK"
     gene            complement(8541..11582)
                     /locus_tag="KR294_003060"
     CDS             complement(8541..11582)
                     /locus_tag="KR294_003060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp20"
                     /protein_id="HBH0241119.1"
                     /translation="MFKQRLSKLLSSTLVLSMLFTAAPNITFADNTKDNSEKYQSSDI
                     ELHDYSKNAESYTKTKALAKEKIQTLLSKYGAVSAQYALIDNGKIEISGNGGVYSKQD
                     NKNLNKDNMYSIASISKMFTTTAVMKLVDDGKLNLDTPVVKYIPEFKMADDRYKEITP
                     RMLLNHSSGLMGSSFKNTILLADNDSYGHDNFLKELQKQRLKAKPGAFSVYCNDGFTL
                     AEILVERVSGMSFTNFLDKYINNPLNLQNTKTPENSFDSSKLAKAYVPYWEDAVPQDN
                     LNAIGAGGLYSSAENLCTFAQTFMKNSNGILSPASVKAMENKEYLNGLWPEGEDSILG
                     YGLGWDCVNTYPFNQYNLKALTKGGDSLLFHSNLIVLPDENMAVAVLSSGGSSQLNEI
                     IGQEILLSALKEKGKIKEIKPDKTFSKPQQVKMPSSLKENSGLYASSNMIKVDVNDNG
                     TLTVSSPYIENGPEDKYVYIGQDRFVSEKGNSCLKFVKEKNNITYLNMSSYDDVPGLG
                     QTASLYYVAQKVDDNNISNSVKEVWKKRSGKGYYLVDEKYTSQSYMFGSVKASFSLSD
                     ETPGYIVNTKIMDENNSNAFIEIPGVIGRDLSDIKLHKENGTEYLSFGTLTYVSEDSI
                     TNLPAEKSFTCELESNGYAKWYKIGDDIANKKIEVNLPQNSAFAVYDDKGVPVNYSLV
                     TKNNRVRLPKGGVIVFLGSPNARFEVTYQDEVNASALTGTDRYETSIKISQAGWENAE
                     NAVLINDSAIADALAATPFAYKKNAPILLTGSSQINEKTLAELKRLKVKNVYVVGGEA
                     SINEKSLDTIKSNNISVSRISGSDRYQTSMNIAKELNNISNISKISVVNGEKGLADAV
                     SIGAVSAQNDMPIILTNENSNITEINNLFKNKKIDKSYVIGGEYTVSKNIESKLQNPQ
                     RISGSTRNETNAKVIKEFYKDSKIDNLYVAKNGMNKQDDLIDGLSVGVLAGKTKSPVM
                     LVGNSLDYNQKELFKTMRFKSVTQIGGNGNENSFKQIKEIA"
     gene            11789..12088
                     /locus_tag="KR294_003061"
     CDS             11789..12088
                     /locus_tag="KR294_003061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HBH0241120.1"
                     /translation="MYKNINKKQLKEMMKNEKDVLLLDVRTKDEFKEYKIENAINISL
                     QELINNIDEIYDYKDKKVVVYCRSGHRSVTACNLLAEEGFEHLYNLNSGIIDYMS"
     gene            complement(12326..14554)
                     /locus_tag="KR294_003062"
     CDS             complement(12326..14554)
                     /locus_tag="KR294_003062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HBH0241121.1"
                     /translation="MRHLKKTNSLKEILNWNNIKNLRPSKGLKNILEIFKSDLKDIRG
                     NYAVLVIVLGLAFLPSLYAWFNIKASWDPYGSTANMLVAVTNEDKGNEIAGQKINVGD
                     QLIEQLKDNKSLGWQFVDEKTALEGVKKGTYYASLKIPKNFTKDLTSLITDDVKKGEI
                     IYTVNEKINAVAPKITDKGASTIQLQVNQTIVKTVSEIVLGISNGVGAGIEHSLPKLT
                     KVENSLIDLQKRFDHINKTVDLASDATSKLSDTVKDIKSDLPTIKKTLNDTKLLSSDL
                     KKFLEDTNDNLDELSPLIKSDLNLMVDLSSSASSLTLNLIDAVNSGSEDVPKLIDNLS
                     EKLSNLQSLNDTLVDFLTKLNQLTSNNRLDDVIDNLEDSSNKIDSSISTLNDIKNKVI
                     SGQQPSISALNNVLSLSNGIGRINLNILNNFDSKISKPINSIFANSIKVANDIITVLD
                     KAEAKLPKVEEILTTSLKLSGNAQESISLIRERLPLAKGMLDDLIDTLSKISNGEDMK
                     KLVSLLESDILTKSNFLKEPVEVKTEKLYPIENYGSAMTPFYSVLSTWVGILLISALL
                     STSVHGNYKPYEIYFGRGLTFLSIALVQGFIIGTGDILLLGVTAKHPILLIVLLMFTS
                     MVFNFIVYSLVSVFGNVGKAIAIVLLVVQIGSSGGTFPIQVTPTFFQRINPIMPFTYA
                     IGATREAVGGIYAPNLTKDILVLLLFMILSICLNVLLKGPINRVIKPFNDKFGDSNLT
                     GH"
BASE COUNT         5581 a         1776 c         2182 g         5123 t
ORIGIN      
        1 tgacctaatt tagaataaat ttctgattta agcttcttag cttttttatg tgtatgaata
       61 tatagtatac tttcatataa taaaaaacct ataataccaa taaaatagga aagttccaat
      121 ttattaaatg taaagaccag aataaaaact aatataaagt ctataataaa acctaaagat
      181 aatagttttt taaattcttt atctaacttt ataaagtaat tataattttt atgctcttgg
      241 tctatagaaa ctccatagat gtgtttttta cctacaaaat agggcataaa ataaaatgta
      301 gcatacatca aaattagaac tggaaatatt gtaaatagac attcaatctt actcataata
      361 tttcacctca tacttgtcaa ataaacttga acttagtgac aaaaattctt ctttactaat
      421 acctgataaa taagattttg ccaccaataa ttccaagtca agtttatttt tttgacgagt
      481 tgtattatct attttcattg gtagttgagc tacaatagca ccttttcttc tatcaatatt
      541 taagaatccc tcttctttta attcattgta ggatttgttc actgtatgta aatttacacc
      601 aatattttca gccatacttc ttacagatgg aagtgattca tttattttca attctcctga
      661 agctatagcc ttagttattt cttctttaat ttgtacataa atagatttat cactattaaa
      721 atctaaattt aaaaccataa aaaacctcca ttatgcttta taaatgaaaa cgattgttat
      781 atacatagta taacataaaa aataataaca aacacaaaat ataagtttat attttgtaaa
      841 aattgtaatt taaaaaataa cataattttt attaaaataa tacagatact atttatagat
      901 agaaataaaa attagaaagg agaaaaaata tgttaacata tttaatgaaa agacaaatgc
      961 ataaaaaaga tgatggaatg agtaaaccaa tgatgattac aggagctgta attacaggtg
     1021 taggagcata tgctgtatat aaaatggtaa aaagccataa atctaattct caaatggtca
     1081 atacaaatta ttatggaaat agcgattatg atgattataa atatgacgaa tttgattatg
     1141 actgtgattg tagagacaca aaacaagatt atgaatatga agaattaaaa aaaaaagtaa
     1201 aagaatttaa ttcaagaaga ataaattgtg aaaattgtcc acatgtttct caagaagaaa
     1261 tgatgcaata tgtaaatagt gttaaagatg taaaggaaga gattgattta catgaagatg
     1321 ctaaaaaaga taatatttac aaagaagatg aatacaaaaa atatgaagaa gaataagtaa
     1381 tattttgtat aactgaacaa atagtaatgt caaattattt aatatctagt tttaatatgt
     1441 aagttgtaac ttaacttgaa agaatcagta tcattcttta gatagttaag taacaactta
     1501 cattttattt ttataaattt taatagttct ttgtgactat tttgtaattt tagaaatatt
     1561 ttagtatcca gggtaattgt gtataataaa acttgtatag atagatagta tgaaattaag
     1621 cagatagttt aaaattaaaa tgaaaagaaa ggaaatagtt atgttaaagt tgttgatagt
     1681 tgaagatgat agtactatat cttttggaat aaagtatgct ttagaacaag aaggatttag
     1741 tatagatata tcaaaggatt tatctagtgg aaaagaaatg atttcttcta atgaatatag
     1801 catgatactg ttggatgtta cattgccaga tggaactggt tatgagcttt gtcaatatat
     1861 aagaggattc tctcaggttc ctataatatt cttgactgct tgtgatgaag aagtaaatat
     1921 tgtaatgggt ctcgatatag gtggagatga ttatataaca aaacctttta gaattagaga
     1981 attaatatcc agaataaaag ctgttttaag aagaaaaggt aatacttcag aagaaaataa
     2041 gaaaatactt aaatttggag atttaagtat atatacatta gaagctagag tatataaaaa
     2101 tgataaagaa atatttctga catcagttga atataaactt cttttaattc ttatacagaa
     2161 taaaaatact gttttaagta gaactcaaat attggaaaaa ctttgggatg taacttatga
     2221 ttttgtaaac gacaatactc taactgttta tataaaaagg cttagagaaa aaataggtga
     2281 tgatttatgt gaaccaatct acatagaaac tgtaaggggg attggttata aatggatagg
     2341 aagtgaaaat agtgtttcta tataatccag aagtgaagaa gtttttaagt aagtatgtta
     2401 ctttgatgtt tattgttatc ataatatcta ttggatttag cataatcaac gtgtccttaa
     2461 ctaaagagat ggttgtaaga aataatcagg ctataatagg aactttatca agcaagtatc
     2521 caaacttgga aagtcagata gtagacataa taactcaagg gaagtctatg gagaacatag
     2581 attatggtca gaaaatatta attaagtata attatgataa atctattagg ataaactctg
     2641 agcctattat ttctaaatta gttttagaga ctatcaaaat aaatataata ttagtatgta
     2701 taatatttat tttgatattt gtgttggttg ttagatattt taagtcaatt tacaatgatt
     2761 tatcagatat gactaagtat gtttactata gttcagaggg taagccattt gatatgaaaa
     2821 acaagaatca agaagggcag ataggtcttc taaaaactga actcttaaag atgacaacaa
     2881 ttcttaatga aaaggttgaa cttttaaaaa gagaaaagat atttttaaac aatacaattt
     2941 ccgatatatc acatcaatta aaaactccta tgacttcttt aataatgttg aatgatttat
     3001 tatataatga tgtaccatac gaagtaaaaa tcgatttttt aaataagata aaaaatcaat
     3061 taaatagaat ggattggttg attaaaagca tgcttaaatt atcaaaggta gaagcaaaag
     3121 tgataaattt taaaaaagat aaggtaaaat ttagtgaact catacataga gcaatgctat
     3181 ctatgaaaat acctatggag attaaaaatc aaaaactgac tatagaggga aatgataatg
     3241 tatcttatat tggtgatatt gattggtccg tggaagcatt agtgaatata atcaaaaatt
     3301 gtgtagaaca tactcctgaa tttggaaata taattataac ctataaagaa aatccattat
     3361 tttctgaact aataataaaa gatgagggtg aaggtataga taaaaaagat ataccacatg
     3421 tatttaaacg attctataga ggaagaagta gttcaaaaga agatagtgta ggaataggtc
     3481 ttgcaatgtc aaaatctata atagaaagcc aaaatggcga tatatatgta aacagcgaaa
     3541 aaggtcaggg tacagaattt catataatat ttcataaaat gtatgatagt gactaatctg
     3601 taatatttaa ttcactttat agtaatagcc aaaacctaat atatgaagta tagaatataa
     3661 atattggagg tagttatgga aattttaaga gtagaaaatc taactaaaag ttatggtaaa
     3721 aatgaaacaa aagttgatgc tataaaaaat gtaagtttat cagttgaaaa aggaacgttt
     3781 atagcaataa caggtccaag tggaagtggt aaaagtacct tattacattt attaggagga
     3841 gttgacagac caactagtgg taaggtttat ataaatgatg ttgatatata taatttaaaa
     3901 actaaggatt tggcgatatt tagaagaaga aatataggtc ttatatatca attttacaac
     3961 ttaattccag tcttaaatgt gaaggaaaac atattgcttc cagcagagct tgacaataga
     4021 gatattgata gagaatattt tgatgattta atgaaaacat taggtctaat tgatagagaa
     4081 aagcaccttc caaaccaatt atcaggaggt caacaacaga gaacctctat aggacgtgca
     4141 ttaattaata gaccttctat aatattagca gatgagccaa caggtaattt agatagtaaa
     4201 aattcaaagg aaatattaga attgttaaaa ttgtcagtaa aaaaatacaa ccagacacta
     4261 ataatgataa ctcatgacaa aaatatggca cttcaagctg atagaattat aagcatagaa
     4321 gatggaatca taaaaagtga tgaggtgatg tagatgaatt tatatacatt actaaccatt
     4381 agatacttaa aacaaaataa aagaagaacc attgtaacca taatcggtat aatactttca
     4441 acagctttaa tttgtggtat aggaaatata tttgaaagtt ttatggatta tcaaatgaga
     4501 gaaactataa agaatgatgg aagtttccat gttacatttt atgatgtaaa tagaaaaaat
     4561 gtggaatatg taacgaaatc agctgaaata gaaaaacatg catttaccaa acaacttgga
     4621 tattctaaat tagaaaatag tgaaaatgct atattaagta taaagcaata tgataaaaat
     4681 gcaataaatg gatataaagt ttctataaaa gaaggtagat ttccagctaa ggaaggagaa
     4741 attgttctaa gtgaaagtat tattaatctt atagatgata agttaaaaat aggagataag
     4801 ataactttaa aagtagggga tatgtttgac tcaagcaaga aaaagattga tagtatgaca
     4861 tttcatgaag gtgattatat agcaaatgaa aaagatagaa cttttaaagt tgttggtata
     4921 attgaaaaac ctgggtttga acgttataat ggaattgcaa cagctatagc ctactttaat
     4981 cctatgaata attacaatga tacaattaat gtatcagtag cagtaagaaa tcctaaagat
     5041 gtgtataaga taagtaataa aataagtaaa aatatatatt caaataaaga taaagaagca
     5101 gtttctgata tgataaaata caatgaacat ttattgaggt tacaaggtgc tagtaagtat
     5161 tcaaatataa ataactctat aaagtctata attatagcag taactatttt agtaatcata
     5221 tgtacaattg ctacagtgta caattccttt agtatttcta taaatgaacg aaaaaaacag
     5281 tttgggatat taaattctat aggtgctaca tctagtcaaa ttaaaagatt agtttttata
     5341 gaaggtatta taattagttt aattggtata ccaataggac taatatctgg aacagtagct
     5401 atagacctat tgtttaaaat tataaataag tattttactg aatcggttgt tactaagatg
     5461 agtttgcaga tagtgtataa tccaataata actattgtta gtataataat agttttgctt
     5521 acaatcttta tatcaattct actacctgca atatcggctt ctaatatttc tcaccttaat
     5581 gtgattaaaa atactggaga gtataaagtg ggcaaaatca aaagctcaag acttattaaa
     5641 atgattttta aaactgaagg agtacttgca tataaaaata ttaggagaaa tagaaaaaaa
     5701 tttataataa ctcttttttc tttaatggta agtataataa tatttatatc ttttagtggc
     5761 tttacattac ttttactaag aggtgaagaa attagaaatt ctcaaagaaa atatgatttg
     5821 tatttaactg caaagaacac agctaggtct gtagaggata ctataagtga actagaagat
     5881 attgatggga taaaaaactt tgaattggca acaggacaat atgtgtctat aagagtaagt
     5941 gaaaataaaa taaataaatc caaggaagat ttaatcagga aatattatca aaaatataag
     6001 attggagata gttatgaata tgatttcagt aataatgaat taatttttcc aggagatttt
     6061 gcagtaaaaa acaaaataaa taacttagta cagggctctt ttaataaaga gagagcaatt
     6121 gaagaaaatg gtgttatatt agttagaaaa agtgcatttg aagaaaatgg gaagaaaggt
     6181 gtagtagaac ttaccaacta taaagtagga gatacagtaa attgtgaata tcttgatgaa
     6241 aatgccttaa gtaaaaaagt aaaggtcaag attcttgcta taactgacga agaacgtcta
     6301 ggtcttggtt atcaaaatat ggggttacaa tttataactt atgatgaagt tgctaaaaat
     6361 ttaaatttaa aattaagtaa aagccttata tttattgatt caggaggaag cattaagact
     6421 aagaaggaaa tagaagcttt ggcaaataaa aataatttta acttttatga tgaaagtgca
     6481 agcaatgaaa gtgaaaaaca agatttaaag gttattaaaa tatttgtata tggttttata
     6541 gtagtgatat ctttagtgag tgttacaaat attctaaata cagtaagtac aagtataaat
     6601 ctaagaaaaa gagaacttgc agtaatacaa tctatagggg ttactcctaa aggatttagg
     6661 aaaatgatat atttagaaag ttttatatat ggtatactgt cattgttgtt tggaatacca
     6721 attagtattg gtataattct aattatgaat aaacttattt caggtgtaat tgaattttct
     6781 ccgattatac cgtggacagc catagttatc tgtatagtaa gtgtttttat aataactttt
     6841 atagcagggt atataccaat gagtaaatta aataaagaaa atataataga taatataaga
     6901 agagaaagta tatagatata aaaataattc ttaactatat aaaatattat tatatcactt
     6961 aaatgatttt ttatttatat aagaaatcta ataataaatt actagaggta tttaactatt
     7021 tagaaagaat tggtattata taaagtaaga gaatatataa taagaaagaa tatttgattt
     7081 tattggaaaa caaaagaaaa agaaggtgat tactatttct catataactg cgaagaatat
     7141 gtataaaagt ttagaggaaa gaataaacaa gtttccacaa ggtgctccac catctgatac
     7201 attatacaaa atactaaatg tactatatac agaacaagaa gcgaagttag ttgctcagct
     7261 tccaataaag cctttcagag taaaaacagc agctaaaatt tggagtgtaa gtgaaagtga
     7321 agcatataga gtattggata aacttgctag taaggctctg atactagata tagaagataa
     7381 taaagggaag aaatatataa tgcctcctcc aatggctggt ttttttgagt ttgccatgat
     7441 gagaacgaga cacgatatag accaaaaact tttggcagag ctttactatc aatatatgaa
     7501 tgtagaagaa gattttatca aagatttatt ttattcaaca gaaacgaagc ttggaagagt
     7561 atacgttcaa gaggaagttt taactaatga taatgaggtt agtattttag attatgaaag
     7621 ggctactcat ataattgatg aatcaactca tataggtata agtatgtgtt actgtagaca
     7681 tagaatgcaa catgttggaa aagcttgtga tgctcctatg gatatatgta tgacgtttga
     7741 caatgtagca aattctttaa taaataataa atttgcaaga cgtgtggata aaatagaatg
     7801 taaagaacta cttcatcaag catatgaaca taacttagtt caatgtggag aaaatgttag
     7861 gaaaggggtt acgtttatat gtaattgctg tggatgttgc tgtgaagcaa tggtagcagc
     7921 taaaagattt ggaaatcttc atccagtaca gacaacaagt tttataccaa atataaacca
     7981 tgaaaattgt gtaaagtgtg gtaaatgtat aactgcatgt ccaatagatg cgataagcaa
     8041 ggttaaggaa gatggtaaag aatatataaa aattgatgag gatagatgtc taggttgtgg
     8101 agtttgtgtt agaaattgcc ataaaaatag cattatgtta ttaaagagag atgaaaaaat
     8161 aataactcca gcaaattcag tacatagagc agttcttatg gcaattgaaa aagggcagtt
     8221 acaaaattta atttttgata ataatgctct ggctagtcat agagctatgg gagctatact
     8281 gtcagctata ttaaagcttg aaccagctaa aaagatttta gccagtaaac aattaaagtc
     8341 agtatattta gataaattgt taagtatgaa tgataaatag aaactaactt aaaaaaggca
     8401 aagttttaga cttatctata tcttaataaa cttatcattt aatatttaaa tttaattttt
     8461 acacatataa aacttataac ttaaataaaa aaaggctata ttcaattaat attacttgaa
     8521 tacagccttt tttagttatg ttaagctatt tcttttattt gcttaaatga gttttcattt
     8581 ccatttccac caatttgtgt tacagattta aatctcatag ttttaaatag ttctttttga
     8641 ttataatcta gtgagtttcc tactagcatt acaggagatt tagtttttcc agccaaaact
     8701 ccaacagata atccgtctat taaatcatct tgtttattca ttccattttt agcaacatat
     8761 aaattgtcta tcttagaatc cttgtaaaat tcttttatta cttttgcatt agtttcattt
     8821 ctagtgctac ctgatattct ctgtggattt tgaagtttac tttctatatt tttagaaact
     8881 gtatattctc caccgattac ataagattta tcaatctttt tgtttttaaa caagttattt
     8941 atttcagtta tattactatt ttcattagta agtattatag gcatatcatt ttgagctgat
     9001 acagctccaa tgcttactgc atcggctaat cctttttcgc cattaactac tgaaatcttt
     9061 gatatattgc taatattgtt caattcttta gcaatgttca tagaagtttg atatctatca
     9121 cttcctgaaa ttctagatac agagatattg tttgatttta tagtatctaa agatttttca
     9181 tttatagaag cttctccacc aactacatat acatttttaa cttttaatct ctttaattca
     9241 gccaaagttt tttcatttat ttgagagctt ccagtcaata atataggagc gtttttcttg
     9301 tatgcaaatg gtgttgcagc caaagcatct gcaattgctg aatcgtttat taaaactgca
     9361 ttttcagcat tttcccaacc tgcttgactt atcttaatag aagtttcata tctatcagtt
     9421 cctgtaagtg cacttgcatt tacttcatct tgatatgtaa cctcaaatct agcatttgga
     9481 cttcctaaga aaacaattac gcctcctttt ggcaatctaa ctctattgtt ctttgtaact
     9541 aaagaatagt ttacaggaac acctttatca tcataaacag caaaagctga attttgagga
     9601 agattaactt ctattttttt atttgcgata tcgtcaccaa tcttatacca ttttgcataa
     9661 ccattggatt ctagttcaca agtaaaagat ttttctgctg gcaaattagt tatagaatct
     9721 tcactaacat acgttagtgt tccaaaagat aaatactctg taccattttc tttatgaagt
     9781 ttaatgtcgg ataaatcacg acctattaca ccaggtattt ctataaaagc atttgagtta
     9841 ttctcatcca ttattttagt gttaactata taacctggag tttcatcaga aagactaaaa
     9901 cttgctttta cagagccaaa catatagctt tgagaagtat atttttcatc cactagatag
     9961 taacctttgc cacttctttt tttccacact tctttgacac tatttgatat attgttgtca
    10021 tctacttttt gagctacata gtataaactt gctgtctgac ctaatccagg gacatcatca
    10081 taagagctca tatttaaata tgtgatatta tttttttctt ttacaaattt taaacaacta
    10141 ttaccttttt cagatacaaa tctatcttga cctatgtata cgtatttatc ttcaggtcca
    10201 ttttctatat aaggagaaga tactgttaaa gtaccattat cattaacatc tacttttatc
    10261 atatttgaag aagcataaag accactattt tcttttaaag agctaggcat tttaacttgt
    10321 tgtggcttac taaatgtttt atcaggtttt atttctttaa ttttaccttt ttcttttaat
    10381 gcagatagta agatttcttg tccaattatt tcattaagtt gactacttcc accagaagaa
    10441 agaactgcaa ctgccatatt ttcatctgga agaactataa gattactgtg gaataataaa
    10501 gaatctccac cttttgtaag agcttttaaa ttatactgat taaatggata agtgttgaca
    10561 caatcccacc ctaaaccata tccaagtata gagtcttctc cttcaggcca tagaccattt
    10621 aaatattctt tgttttccat agcttttact gaagcaggag aaagaatacc atttgaattt
    10681 ttcataaatg tttgtgcaaa tgtacataga ttttctgcac ttgaatataa accacctgca
    10741 cctatagcat taaggttatc ttgtggaact gcatcttccc aataaggtac atatgctttt
    10801 gctagttttg aactatcaaa actattttct ggagtttttg tattttgtaa gttaagtgga
    10861 ttatttatgt atttatcaag aaaattagta aatgacatac cagatactct ttctactaaa
    10921 atttcagcta aagtaaatcc atcattacaa taaacagaaa aagctcctgg tttagctttt
    10981 aatctttgtt tttgtaattc ttttaagaaa ttatcatgac cataagaatc attgtctgct
    11041 aataaaatag tgtttttaaa actacttccc atcaaccctg atgagtgatt taataacatt
    11101 cttggagtga tttccttgta tctatcatca gccattttaa attcaggtat atactttaca
    11161 acaggagtat ctaaatttaa ttttccatca tcaaccaact tcataacagc tgttgtagta
    11221 aacattttac tgatagatgc gatactatac atattatcct tatttaagtt tttgttatcc
    11281 tgtttgctgt aaactccacc attaccagaa atctcaattt tgccattatc aatcaaagca
    11341 tattgagcac ttacagcacc atactttgat agcaaagttt ggattttctc tttagcaaga
    11401 gctttagttt ttgtgtaaga ttccgcgttt ttactataat catgtaattc tatatcagaa
    11461 ctttgatatt tttcggaatt atcttttgta ttatcagcaa aagtaatatt tggagcagca
    11521 gtaaataaca tactcaatac taatgtacta gataataatt tagagagcct ttgcttaaac
    11581 atattacatt acctctttcc ctttttaata atttataatt agcataacat tcttaattat
    11641 tttaatcaac agattattat caataaaaaa agcttttata agtatagctt tttatataac
    11701 agagaaaaat ataaaaataa tatttgttgt tgtataaaga ataaagggta taggtaatat
    11761 ataaataaaa tggaggaatt ttagacatat gtataagaat ataaataaga agcaacttaa
    11821 agaaatgatg aaaaatgaaa aggatgtttt attattagat gtaagaacta aagatgaatt
    11881 taaggaatat aaaatagaaa atgctataaa tatatcttta caagagttaa tcaataatat
    11941 agatgaaatt tacgattata aagataagaa agtagtagtt tattgcagaa gtggtcatag
    12001 aagtgttact gcatgtaatt tgttagctga agaaggtttt gagcatttat ataatttaaa
    12061 ttcaggaata attgattata tgagttaaat aatgtaagtt atacattaaa tactatgtat
    12121 agctctgctt attaagtagg aatatatcta aatatttata agataaattt aggaaagaac
    12181 gaattttttc gtttttttct atgacagttt ttgtagtaaa tattagtttt taagttggaa
    12241 aaaggtagta gctttttagc tactaccttt taatatgaac ttagaatatt attaaaaaaa
    12301 tatatttaaa gacagaatta attttttaat gaccagttaa attactatcg ccgaatttat
    12361 cattaaatgg ttttataact ctatttatag gtccttttag aagtacattt aaacaaatag
    12421 acagaatcat aaatagtaat agaactagta tatctttagt tagatttgga gcatatatac
    12481 caccaactgc ttcccttgta gcacctattg cataggtaaa tggcattata gggtttattc
    12541 tttggaagaa tgtaggtgta acttgtatag ggaatgtacc accagaagaa ccaatctgaa
    12601 cgactaatag tactattgca attgcttttc ctacatttcc aaatacagaa actaaagaat
    12661 acactataaa gttaaatacc atactagtaa acataagcag aactatcaat aaaattggat
    12721 gttttgctgt tactcctaac aataatatat ctccagttcc tattataaaa ccttggacaa
    12781 gagctatact taaaaaagta aggcctcttc caaagtaaat ttcataaggt ttatagtttc
    12841 catgtacaga tgtagacaat agtgctgaaa taagtaatat accaacccat gtagaaagaa
    12901 cactataaaa tggtgtcatt gcagaaccat aattttcaat tggatataat ttctctgttt
    12961 tcacctcaac aggttctttt aagaaattag actttgtcaa tatatcactt tcaagcaagc
    13021 tgactaattt tttcatatct tcaccattac taattttgct taaagtatca atcaaatcat
    13081 ccaacattcc ttttgctaaa ggaagtcttt ctcttatcaa tgatatactt tcctgtgcat
    13141 ttcctgaaag ttttagagaa gtagtaagta tttcttcaac ctttggaagt tttgcttctg
    13201 ccttatctaa aacagtaatt atatcatttg ctacttttat actgtttgca aatatactat
    13261 ttataggttt tgatattttt gagtcaaaat tatttaaaat atttaaatta attcttccaa
    13321 taccatttga tagacttaaa acattattca aagcacttat agatggttgt tgtccagata
    13381 taactttgtt tttaatatca tttaatgttg atatagatga atctatttta ttgctagagt
    13441 cttcaagatt atctatgaca tcatccaatc tattatttga tgtaagttgg tttaatttag
    13501 ttaaaaaatc caccaaagta tcatttaaag attgcaaatt agaaagtttt tctgataaat
    13561 tatctatcaa cttaggtaca tcttcactgc cactatttac tgcatcaatt aaatttaatg
    13621 taagagaaga agcagaagat gaaaggtcaa ccattaaatt taagtcagac ttaataagag
    13681 gagaaagttc gtctaaatta tcatttgtat cctctaagaa tttttttaag tcacttgata
    13741 atagttttgt atcattcaga gtctttttaa ttgtaggtaa atcagattta atatctttaa
    13801 ctgtatcaga taattttgaa gtagcatcag aagctaaatc aacagtctta tttatatggt
    13861 caaatctctt ttgaaggtca ataagggaat tttcaacttt tgtcaatttt ggaagactgt
    13921 gttcaattcc tgcaccaact ccgtttgata taccaagaac gatttcacta actgttttta
    13981 ctatagtctg attaacctgt agttgtattg tagaagcacc tttatctgta atctttggtg
    14041 caactgcatt tattttttca ttaacagtat agataatttc gcctttttta acatcatctg
    14101 taattaaaga tgtcaaatct tttgtaaaat tttttggaat cttaagtgat gcataataag
    14161 tacctttttt aacaccttca agagcagttt tttcatctac aaactgccaa cctaaactct
    14221 tgttatcttt gagttgttca attaattggt ctcctacatt aatcttttgt cctgctattt
    14281 catttccttt atcttcattt gttactgcta caagcatatt agcagtgctt ccataagggt
    14341 cccaagatgc ctttatattg aaccaagcat acagagatgg taaaaaagca agacctaaaa
    14401 ctattacaag tacggcataa ttgccacgta tatcttttag gtcactttta aaaatttcta
    14461 atatattttt taaacccttt gaaggtctta aattcttgat attattccag tttaaaattt
    14521 cttttaaact attagttttt ttcaaatgtc tcacctccta aaatattttg ataaagaaaa
    14581 aagttagatt tataatcaat tttaaattat attacttttt acacaaatag taaagttaaa
    14641 attttgtctt aattttaata ca
//
LOCUS       DAEPKC010000101        14573 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.101, whole genome shotgun sequence.
ACCESSION   DAEPKC010000101 DAEPKC010000000
VERSION     DAEPKC010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14573)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14573)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14573
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.101"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..606
                     /locus_tag="KR294_003063"
     CDS             <1..606
                     /locus_tag="KR294_003063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBH0241122.1"
                     /translation="ISGYLTKKLQDLNVDTIRTDILTSPTVTDVIVWNIEQSGTDTFS
                     ATYEVDQQIKEGEQTTTVKATYTVKVHVDADRDMVIIQNPTLAPAIEKSDYEPKTPEA
                     DASVDADTVNDATAFLETFFKLYPTATAKELAYYVFGNVLEPIGRDYLYSELVNPVLT
                     KDGDNMKVKVAVKFLDNQTKATQVLQYELILHKDSNWKIIM"
     gene            819..1676
                     /locus_tag="KR294_003064"
     CDS             819..1676
                     /locus_tag="KR294_003064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002585362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBH0241123.1"
                     /translation="MYKEVGISSNNVPITLSIWYTERSSPTIVFLPGTMSHPLMYENF
                     LCGLSERGFNIIGIHYLSHGKSPKIKKNYTMEDLLHNVYDATTYGIENFGENIAVMGS
                     SQGGILAAMAAGRDTRLKAVFPHNIMLTTLKETMSLTKYPTWSHRFMGLIQWGFRVGG
                     KLLPNYKVPGDAYLDYDRVFYSEQAKQDCLNDPMLLPYYPLRFVTSLFNADLSCLENG
                     AIQCPVILITAKGDPLFSFDYTNKVFDLIHVPQKELLALELNRHMIFNEDTDTTINAL
                     EATLHKYLG"
     gene            1754..2335
                     /locus_tag="KR294_003065"
     CDS             1754..2335
                     /locus_tag="KR294_003065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH0241124.1"
                     /translation="MPRFTEQEKEIINSKLLIEGEKLFALHGLKKVTVDDLVAAVNIS
                     KGSFYAFYPSKEHLYVEINFRLQKELFTSIETTIKKKKYKNHRDLAKDVIMLSLTGVI
                     TSPILSQIDLSLMDYLQRKISSDIFENHMYSDIRILEILEDLGVVFLVPHTVIIKSLY
                     SVLSCLEQFKEDEELNMIQNLLVNGIIQQVVAE"
     gene            2439..3284
                     /locus_tag="KR294_003066"
     CDS             2439..3284
                     /locus_tag="KR294_003066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0241125.1"
                     /translation="MIDVKKLYFSYTDKPFVENVSFHVGRGEIFGFLGPSGAGKSTIQ
                     KVLTGLNTRYKGSVKVAGTEIREHTNQFYENIGVDFEFSTCYEKFTARQNLAYFASLY
                     EKQPRSIDELLHMVGLENDGDKKVADFSKGMRSRLNFIKALVHDPDILFLDEPTSGLD
                     PTNSRLMKDIILAEKKRGKTIIITTHNMFDATELCDQVAFIVAGKVSALDSPHNLIMS
                     RGAAKIQYTYYDKGEKTGECLLDRTTEDKLLKSLISENRLLSIHSSEPTLNDIFVDIT
                     GRTLQ"
     gene            3281..3964
                     /locus_tag="KR294_003067"
     CDS             3281..3964
                     /locus_tag="KR294_003067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016295773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0241126.1"
                     /translation="MRLGRLICGDIHFQWKYGFYFIYFILTVLYVCGIAALPEHWKTD
                     IASIMIYSDPAAMGLFFMGAIVLLEKSQKVLNAMVVSPVKISEYILSKTVALIAISTV
                     IALILGVVSGSNHLLGIAVGTALTSAIFTMLGIIAATKISNLNQFLIVIMPIEIICFV
                     PPIVGLFVKLPYLFRFFPFTACMNLITGKSVLLSFDMVLVIATLIILYIVARHTVEHM
                     WKSLGGVKL"
     gene            3961..4659
                     /locus_tag="KR294_003068"
     CDS             3961..4659
                     /locus_tag="KR294_003068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002583502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0241127.1"
                     /translation="MKKILSSTIQIFKQIKSDPMMFAACFSPFIMGTLIKFGIPFLER
                     ITKFSLQAYYPIFDLLLSIMAPVLLCFAFAMITLEEIDDKVSRYFSITPLGKSGYLFT
                     RLGVPSIISAVIAFIVLLLFSLEKLSIGMTICLALLGSVQAIIVSLMIITLSSNKLEG
                     MAVTKLAALTLLGIPAPFFIDSYYQFAVGFLPSFWVAKAMQNEAVLYFSIGLVVALVW
                     YYFLTKRLFRKLAG"
     gene            4671..5582
                     /locus_tag="KR294_003069"
     CDS             4671..5582
                     /locus_tag="KR294_003069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBH0241128.1"
                     /translation="MEKGRLLQNKNMNKAIQVSKITLIINLSLSLLKFAAGYIGKSSA
                     MLSDAVHSASDVVSTIVVMVGIKISEKQPDREHPYGHERMECVASIILSVALAITGAG
                     IGYSGIKKIFSGQYNTLSVPSGIALTAAVLSIVIKEWMYWFTRSAAKHTNSDALMADA
                     WHHRSDALSSVGSLIGILGARLGYAILDPIASVVICGCILKAALNIFKESINKMVDHS
                     CDNATETRIREVVLQQQGVDGIDELKTRMFGAKMYVDIEILADGNLALYDAHRIAEGV
                     HQTIENNFPQCKHCMVHVNTNELLYSA"
     gene            5634..5774
                     /locus_tag="KR294_003070"
     CDS             5634..5774
                     /locus_tag="KR294_003070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241129.1"
                     /translation="MEQYWWIIIVVVLIVVGLLKIVIMKKYNQRRNSNNRSKDSEDDK
                     MY"
     gene            6065..6691
                     /locus_tag="KR294_003071"
     CDS             6065..6691
                     /locus_tag="KR294_003071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH0241130.1"
                     /translation="MSDTKENILKIALHLFAVNGYEAVSVSMIAEALGMTKGALYKHY
                     KNKQDIFDCIVERMYQIDNKRAKDYQVPESTIEVTPNAYRNTTIGSLITFTLAQYDFW
                     VTDEFASNFRKMLILEQYRNLKMNMLYQKCLVNGPISYIEDIFNEMIEKGVLQECDTK
                     QLAIEYYAPLFLLISVADAVENCWDLKTQLTTHVKQFVKKYIINEKVK"
     gene            6813..7529
                     /locus_tag="KR294_003072"
     CDS             6813..7529
                     /locus_tag="KR294_003072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBH0241131.1"
                     /translation="MEYIRSKKYFTPDLQTKIMGPNPIKLQEELLQNHKIPSGSYVCD
                     LGSGQGLTSVFLAKEYGFVVFAVDLWSEPKENEEFFKKMGLSSAQIKSVKADANELKF
                     EKEFFDAVVSTDSYNYFGRDPIYLDEKLLPFVKKGGFVYITVPGMKKDCHEKLPEELL
                     LSWTPEELDYIHDITYWSNIISHCKKADLISIYEMESNSEVWSDWIKQNNEYAINDRK
                     AIEAGGGDYLNFIAIILQKK"
     gene            7679..8275
                     /locus_tag="KR294_003073"
     CDS             7679..8275
                     /locus_tag="KR294_003073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015541496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HBH0241132.1"
                     /translation="MKILWIIIIMADNLLPLLLARFYPNYKHKEMALSVLGSRQSPVK
                     WIYNVWCIISGVVFCIAPYALYQENDSGWAIAIWMLLAIYGIGCEIISGVCPLNENRQ
                     DEDIITKIHGGTSAIGFMALLVVPLLFAILQFQTTKVVLGAISLVCFTIAFIFFCFFI
                     MGEKEKFANTVLRYGGLWQRLVLISCYIPLFVWSVSNQ"
     gene            8362..8553
                     /locus_tag="KR294_003074"
     CDS             8362..8553
                     /locus_tag="KR294_003074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003064779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4177 domain-containing protein"
                     /protein_id="HBH0241133.1"
                     /translation="MKKYEYVEINYNAKGVVFLCTDKHKEIIDSYAKTGYHYAGFVPT
                     EIDAKGCMRKIDLIFEKED"
     gene            8577..8807
                     /locus_tag="KR294_003075"
     CDS             8577..8807
                     /locus_tag="KR294_003075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241134.1"
                     /translation="MIGLKRRDMNYIMKVGAKAQGVSVSEFRAMLQDTIDKTMESTDP
                     DVQANFKRYFGNKRPTPEEYIYTITKKTKVKV"
     gene            9074..9493
                     /locus_tag="KR294_003076"
     CDS             9074..9493
                     /locus_tag="KR294_003076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009261829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBH0241135.1"
                     /translation="MKPSDFQKTIQCQFECKLKKVVKGIIWNYRKELKRRKNKEISFS
                     ELPDITVESLATWDDYETNYTIFNVCGIDIKVLDDELAEALKQLPEKKRNNVLMYYFL
                     EMSDTEIADIMNYTRGAVFKHRHRALETMKEILKEKK"
     gene            9496..9750
                     /locus_tag="KR294_003077"
     CDS             9496..9750
                     /locus_tag="KR294_003077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH0241136.1"
                     /translation="MKKKYKHPSYYLISSAMDGDETAIEKLLAFYDPYISKCCLRPLY
                     DEYGNVYIVVDMELKGRIREALIKMILDFEIDIDIETEEE"
     gene            10125..10328
                     /locus_tag="KR294_003078"
     CDS             10125..10328
                     /locus_tag="KR294_003078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HBH0241137.1"
                     /translation="MNNTDVPIWEKYTLSIEEASRYFRIGEKKLRKLAEENLDSGWVI
                     VNGNRIQIKRKQFEKIIDTLDEI"
     gene            10406..11596
                     /locus_tag="KR294_003079"
     CDS             10406..11596
                     /locus_tag="KR294_003079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006354938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBH0241138.1"
                     /translation="MSKMKRQDSKGRNLRLGESQRKDGRYVYKYTDIFGKPQFVYAWK
                     LVPTDKTPTGKRDDKSLREKEKQIKKDLDDGIDTIGGKMTVCQLYAKKNNQKKNIKRN
                     TEIGRQYLMNALENDPLGMRAIDTVKQSDAKEWAIRMNDKGYSYKTIDNYKRSLKASF
                     YMAIQDDCIRKNPFHFKLSDVLEDDTEPKVILTPEQEEKLLSFMETDNVYSKYRDEVI
                     LLLETGLRISELCGLTTHIDMLNRVINIDHQLLRDTEVGYYISTPKTKNGKRELPLTE
                     RAYQALERILKNRGKAQPLVVDGYSNFLFLNREGLPKVAGNYESMVRGLIKKYNKTHE
                     DKLPNITPHSFRHTYCTNMANKGMNPNTLQYIMGHANITMTLGYYAHGTFQSAKAELE
                     RLAS"
     gene            complement(11853..12653)
                     /locus_tag="KR294_003080"
     CDS             complement(11853..12653)
                     /locus_tag="KR294_003080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0241139.1"
                     /translation="MRLNKRSEGYINYVKGVKREKRNVLFYQLLILIGFIVIWELLAD
                     LNVINTFLFSKPSDIYNLFIQYAFSGQLFKHIGISVYETVLGLVIGTVLGILVAIALW
                     WSEKLSKILDPFLVVLNALPKTALAPIIIVWVGAGIEGIVVTAVTISVVVTILSAYNY
                     FMNIDEEKIKMLKSFGATKSQILFKLILPANTGNLINLTKINIGMAWVGVIVGEFLVS
                     RYGIGYLIVYGSQVFKLDLVMMGVFVLAICAWAMYAVVNIIEKIYNSR"
     gene            complement(12848..14446)
                     /locus_tag="KR294_003081"
     CDS             complement(12848..14446)
                     /locus_tag="KR294_003081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBH0241140.1"
                     /translation="MKAAIYSRKSRFTGKGDSIENQIQLCIDYAKSIGVKDFLIYEDE
                     GFSGSNIDRPQFKKMMQDAKDKKFSYLVCYRLDRISRNVSDFSTLIEKLNELSISFIS
                     IKEQFDTSTPMGRAMMFISSVFAQLERETIAERIKDNMYELARSGRWLGGNTPHGFNS
                     EKITFLDENLKERSMYKLQVNDEQMEIVKLIYNKYLELRSLSKLYKYVYNNGIRGPRG
                     GKFDPSSLSRILRNPAYVKANDEILDYLKNSGMDVVGTPDRKCGILTYAKNTSNSIAA
                     IAKHHGVIEPEIWLEVQNQLDKNRDKTPRISTGKTALLSGLIKCGKCGSNMRITYKGK
                     KTDKDLKYYYICGTKKTLGSDSCNCKNLNGPLVESLVIDKIKNCKEESIISAFNSNNI
                     KTDNVFNIFKSETNLLKNQILDKERLIKNLVIELAKNTGSTASDYIVSQIESLNNEIS
                     ILKDKINILESSNINISSDSINIDIIVSNLKRFNDEVDNASLDDKRLLLSTIINSIVW
                     DSSLGNLNIVYMGAEVDNSVSLSN"
BASE COUNT         4914 a         2355 c         2691 g         4613 t
ORIGIN      
        1 atcagcggtt atctaacaaa gaaattgcag gacttgaatg ttgatactat tagaaccgat
       61 atactgacta gccccacagt tacagatgta attgtgtgga atatcgaaca gtcgggaacg
      121 gacacttttt ctgctaccta cgaagtagat cagcagataa aagagggaga acagacaaca
      181 acagtcaagg caacctatac ggtaaaagtc catgtagacg ctgacaggga tatggtaatt
      241 attcagaacc ctacccttgc accagcaatc gaaaaatcgg actatgagcc aaagacacca
      301 gaagcagacg caagtgtaga cgctgatacc gtgaatgacg ctaccgcatt tctggaaaca
      361 ttctttaagc tgtacccgac agccacagca aaagagcttg cctattatgt atttggaaat
      421 gtgcttgaac ctatcggcag ggactacctt tattcagaat tggtaaaccc agtacttaca
      481 aaggacgggg ataatatgaa agtcaaggta gctgtaaaat tccttgataa tcagacaaag
      541 gcgacgcagg tattgcagta tgagcttatt ctacataagg atagtaactg gaaaattatt
      601 atgtaagaca ttttgttggc aggatctatt ttcggatata gtctgccttt tctgtagcaa
      661 atgtactgca ctgacaagct atttcattgt attttaagca attaaacctt tcttgacaat
      721 tttatcttaa atcatatatt tatggatatt gactttctgc ttgcaataag ctataatatg
      781 actataaaat caaatcagtc atataggagg tatgtggtat gtataaagaa gttggtattt
      841 cttcaaataa tgttccgata acactttcta tctggtatac agaaagaagt agtcctacca
      901 ttgttttttt gccgggtact atgtcacacc ctctcatgta tgagaatttt ctatgtggtt
      961 tgagtgaaag aggatttaat ataataggca ttcactatct ttcacacgga aaaagcccta
     1021 aaatcaaaaa aaattataca atggaagatt tgctgcataa tgtatatgac gcaacaactt
     1081 acggaataga aaatttcggt gaaaacatag ctgtcatggg ttccagtcaa ggcgggattt
     1141 tagctgcaat ggcggcaggt agggacacaa ggttaaaagc cgtttttcca cataatatca
     1201 tgctgaccac attaaaagaa actatgagct taacaaaata tcccacatgg tcgcaccgtt
     1261 ttatggggct gatacagtgg ggctttcgtg taggtggaaa attgctgcct aactacaagg
     1321 ttccaggaga cgcttattta gactatgaca gagtatttta tagtgaacag gcaaaacaag
     1381 attgcttaaa tgaccctatg cttttaccct attatccttt aagatttgtc accagcttat
     1441 ttaatgctga cttatcgtgc ctggagaatg gggctataca atgtcctgtt attttaatta
     1501 ctgccaaagg cgacccgctt tttagctttg attataccaa caaagtattt gatttaattc
     1561 atgtaccgca aaaggaatta cttgctttag agcttaatcg tcacatgatt tttaatgagg
     1621 acacggacac tacaataaac gcattggaag ctaccttgca taaatatctt ggatagcata
     1681 ttgattatat aatcagtaaa tgttatactt ttcatgacga tataaatatt ttagtcataa
     1741 ggaggttatg agtttgccac gatttacgga acaagaaaaa gaaatcataa acagtaaact
     1801 tttgatagag ggagaaaagc tgtttgcatt acacggctta aaaaaagtaa cagttgatga
     1861 tttagtagct gctgtaaaca tatcaaaagg ttctttctat gctttttatc ccagtaaaga
     1921 acatctatat gttgaaatca attttcgctt acaaaaagag ttatttacaa gtatagaaac
     1981 aaccattaaa aagaaaaagt ataagaacca tagagattta gcaaaggacg ttatcatgct
     2041 aagtttaacg ggggtgatta cttcgcctat tctttcacag attgatttat ctttaatgga
     2101 ctatctgcaa agaaaaatat cgtcagatat ttttgaaaat catatgtaca gtgatattcg
     2161 tatattggag atattggaag atttaggggt tgtatttttg gttccgcata cggttattat
     2221 aaaatccctg tattctgtct tatcctgttt ggaacaattc aaagaggacg aagaactgaa
     2281 tatgatacaa aatcttttag tgaatggtat tattcagcaa gtagtagcag agtaacaatt
     2341 ttgtttggtt atttgacagg caggtagcca aacaaatttt ttacagttta tatgactata
     2401 tatctataaa cgtcataaag ttaaaggagg aatgaataat gattgatgta aaaaaactgt
     2461 attttagcta tactgacaaa ccgtttgtgg agaatgtaag tttccatgtt gggagaggag
     2521 aaatttttgg ttttttagga ccctctggtg ctggaaaatc aactattcaa aaagttttaa
     2581 ctgggcttaa tacaagatat aaaggcagtg taaaagttgc aggtacagaa ataagggagc
     2641 atacaaatca gttttatgaa aatattgggg tagactttga attttcaacc tgctacgaga
     2701 aattcacagc acgacaaaat ctcgcctatt ttgcttctct atatgaaaag caacctcggt
     2761 ctattgatga attattgcat atggtaggct tggaaaatga cggggacaaa aaagttgctg
     2821 acttttccaa aggtatgcgt tctcgcttga atttcattaa agcgttagtc catgaccctg
     2881 atatattatt ccttgatgaa cctacaagcg gtcttgaccc tacaaatagt cgtttaatga
     2941 aagatattat tcttgcggaa aagaaacgcg gaaaaacgat tatcattact actcacaata
     3001 tgtttgacgc aacagagcta tgtgaccaag tagcctttat cgttgccgga aaagtcagtg
     3061 cattggatag cccgcataat ttgattatgt caaggggagc tgccaaaata caatatacct
     3121 actatgataa aggcgagaaa accggagaat gtctgcttga tagaaccaca gaagataagt
     3181 tgttaaaaag tttaatttcc gaaaaccgtt tgctttctat tcatagtagt gagcctacat
     3241 taaatgatat ttttgttgat attacaggga ggacacttca atgagattgg gacgtttaat
     3301 ttgtggtgat atacatttcc aatggaaata tggtttctat tttatctact ttatattaac
     3361 agttttatat gtgtgcggga ttgccgcttt gccggaacat tggaaaacgg atattgcttc
     3421 tattatgatc tactctgacc cggcagcaat gggattattt tttatgggag cgattgtcct
     3481 cttagaaaaa agtcaaaagg tgttaaatgc tatggtggta tcccctgtaa aaatatcgga
     3541 atatatactt tcaaaaacag ttgcgttgat tgctatttct acggtaatcg cattgatatt
     3601 aggggtagtt tccggcagca atcatttact gggtatcgca gttggtacgg ctttgacctc
     3661 agcaatcttt actatgcttg gaattattgc agctacaaaa atttcaaact tgaaccaatt
     3721 tctcattgtg attatgccga tagaaattat ttgctttgta ccacctattg ttggtctgtt
     3781 tgtgaagtta ccatatctgt tccgcttttt tccattcaca gcttgcatga accttataac
     3841 tggaaaaagt gttttactat cgtttgatat ggtacttgta attgctacgt tgattatcct
     3901 ctacatagtt gctcgacata cagttgagca tatgtggaaa agtttgggag gtgtaaagct
     3961 atgaaaaaga tattatccag caccatacag atatttaagc aaatcaaaag tgaccctatg
     4021 atgtttgcgg cttgcttctc cccttttatt atggggactt taattaagtt tggtattcca
     4081 tttcttgaaa gaataacgaa gttttcttta caagcgtatt atccgatttt tgatttatta
     4141 ctttctatca tggctcctgt attgctctgc tttgcatttg caatgattac attggaggaa
     4201 atcgacgata aagtgtcacg gtacttttcg attacccctc ttggtaagtc ggggtatctc
     4261 tttacaaggt tgggagtacc ctcaattatt tcggcggtca tcgcttttat tgtactgtta
     4321 cttttttcat tagaaaagtt gtccattgga atgacaatat gtttggcgct tctcggctca
     4381 gtacaggcaa ttattgtttc acttatgatt atcacattat caagcaataa attagagggt
     4441 atggcagtta caaaactagc tgcacttaca ttgctcggaa taccagcccc cttttttatt
     4501 gatagttact accagttcgc ggttggcttc cttccatcat tttgggtagc gaaagccatg
     4561 cagaatgaag cggttcttta tttctccata ggattggtgg tagctttagt ctggtactac
     4621 ttccttacaa aacgtctgtt tcggaagctg gcaggataag gaggcatatt atggaaaaag
     4681 gtagacttct gcaaaacaaa aatatgaata aggctattca ggtttccaaa attacactaa
     4741 tcatcaatct gagtttatcg ctacttaaat ttgctgccgg atatatagga aagtcaagtg
     4801 ccatgctgtc ggacgctgta cattcggctt ctgatgtagt aagcacaatc gttgtgatgg
     4861 ttggaattaa aatatcagaa aaacagcctg atagagaaca tccttatggg catgaacgta
     4921 tggaatgtgt ggcttccatt attctctctg ttgcattggc tataacgggt gctggaatag
     4981 gatattcagg tatcaagaaa atcttttcag gacagtacaa tacgctttct gtccctagtg
     5041 gaatcgcact tacggcagca gtcttatcta ttgttataaa agagtggatg tactggttta
     5101 caagaagtgc tgcaaagcat acaaattctg acgcacttat ggctgacgca tggcaccacc
     5161 gctctgatgc actctcgtcg gttggttcct taattggcat tttaggagcg cgtttaggct
     5221 atgctattct cgatcctatt gcaagcgttg tgatttgcgg ttgtatctta aaagctgctt
     5281 tgaacatttt caaagaaagc attaacaaaa tggtagacca tagttgtgac aatgctactg
     5341 aaacaaggat tagggaagtt gtgcttcagc agcaaggggt tgatggtatt gatgaattaa
     5401 aaacccgcat gtttggagcg aaaatgtatg tagatattga aatattagct gatggtaatt
     5461 tagctcttta tgacgctcat agaattgctg agggagtcca tcaaacgatt gaaaacaact
     5521 ttccacaatg taagcattgt atggtacatg ttaatacgaa tgaacttctc tattctgcat
     5581 aggacaggga agatgattta aggctattga aagggaaagg agggaagtag gttatggaac
     5641 aatactggtg gattatcatt gttgtggttt tgattgtcgt tggcttactt aaaattgtaa
     5701 ttatgaagaa gtataaccaa aggagaaatt ctaacaatcg ttcaaaagat agcgaggacg
     5761 acaagatgta ttaaggttta ttgaaatctg ttatgttgta gaatgatgtt tttagatact
     5821 agaaagtgct ttaagggggg ctaacgttaa ggaaagcttt gagtacaatt ctttacaatc
     5881 aacagtcttt tgcatagaga aatgtatgta ggaaatatgg tgcaaggcac aaaacaccag
     5941 caattgagaa atcaacctat gaaccaaagg cacactacat tttatactac ttgacaagta
     6001 aacgaacatt tactttaatg gtttaaagaa gtaaacgttc gtttactaaa gaaggaggtt
     6061 gtaaatgtct gacacaaaag aaaatatatt aaaaattgca ctacacttat ttgcagtgaa
     6121 tggttatgag gctgtttctg ttagtatgat tgcggaagcc ttgggaatga caaaaggagc
     6181 attatataaa cattataaaa ataagcaaga tatttttgac tgtatcgtag aacgtatgta
     6241 tcaaattgat aataagcgag ctaaggatta tcaagtacca gaaagcacaa tagaggtaac
     6301 cccaaatgca tacagaaata caactattgg aagtctaata acatttactc ttgcacaata
     6361 cgatttttgg gtgactgatg aatttgcgtc taattttcgc aaaatgttaa tactagagca
     6421 atatagaaat ttaaaaatga atatgcttta tcaaaaatgt cttgtaaatg gtcctatcag
     6481 ttatatagaa gatatattta atgaaatgat tgaaaaaggt gttcttcaag agtgtgatac
     6541 aaaacagctt gctattgaat attatgcgcc attatttcta ttgataagtg tagcagacgc
     6601 agttgaaaat tgttgggatt taaaaactca attaactaca cacgttaaac aatttgtcaa
     6661 gaaatatatt ataaatgaga aagtaaaata atcctttatt ctgtcctaaa tataaaccta
     6721 actttttaat ttcagcagag aaactcaaaa tgaatattgt tataagtcac aaatattaac
     6781 tattaaaata ttacaataac ggagatgaga aaatggaata tattcgcagt aaaaaatatt
     6841 ttacacccga cttacagaca aaaattatgg ggccgaatcc tataaaatta caagaggaac
     6901 tattacaaaa tcataaaatc ccgtctggta gctatgtctg tgaccttgga agtggacaag
     6961 gtttaacttc tgtatttctt gcaaaagaat atggatttgt tgtttttgca gttgacttat
     7021 ggagtgagcc aaaagaaaat gaagaatttt tcaaaaaaat gggattatct tctgcacaaa
     7081 ttaaatctgt aaaagctgac gccaatgaac ttaaatttga gaaagagttt tttgatgctg
     7141 tagtaagtac agattcatat aattattttg gacgtgaccc tatatattta gatgaaaaat
     7201 tgcttccatt tgttaagaaa ggtgggtttg tttatatcac agttcctggc atgaagaaag
     7261 attgccatga gaaacttcca gaagagttat tgttatcatg gacaccagaa gaacttgatt
     7321 atatacatga tataacatat tggtctaaca taattagtca ttgtaaaaag gcagatttaa
     7381 tttcaatata tgaaatggaa agtaattcgg aagtttggtc ggattggata aagcaaaata
     7441 atgaatatgc aataaatgac cgtaaggcaa tagaagctgg cggtggagat tatctgaatt
     7501 ttattgctat aattctacaa aaaaaataaa ttctttagaa ccaaacacta taatttgcgt
     7561 tctaatatgt ttaccgattg acatcaataa ttttatcttt gagggtaatg atttgaaaat
     7621 agaagaatac aagaagatac gaaattgata aattagaatt tgatgggatg gtgatattat
     7681 gaaaatatta tggatcatta ttattatggc agataatctg ctgccgttac tgcttgctcg
     7741 tttctatcca aactataagc ataaagaaat ggcactatct gtccttggct ctcgtcaaag
     7801 cccggtgaaa tggatatata atgtgtggtg cattatatca ggtgtggtat tttgtatcgc
     7861 tccatatgcg ttgtatcaag agaacgatag cggatgggca atcgctatat ggatgcttct
     7921 tgctatatac ggcatcgggt gtgaaatcat ttccggagtg tgcccgttaa atgaaaatag
     7981 acaagacgaa gatataatta caaaaattca cggcggcaca tcggcaatcg gatttatggc
     8041 cttgcttgtc gttcctttgc tctttgcaat tctgcaattc caaacaacaa aagtagtgtt
     8101 aggcgcaatt tcactggtgt gctttacaat agcattcata ttcttctgct tttttattat
     8161 gggtgagaag gaaaagtttg caaatactgt tttgagatat ggcggtcttt ggcaaaggct
     8221 tgttttaata agttgttata taccgttatt tgtttggtct gtttctaatc aataaaattt
     8281 agtttatagg aataacaaat tccagtttgt aaaagtcaat aaatccaaag ataaatttgt
     8341 atttgaaagg agttttgaag aatgaaaaaa tatgagtatg tagaaattaa ctataatgcg
     8401 aaaggagttg tattcctttg tactgataaa cacaaagaaa ttattgacag ttacgcaaaa
     8461 acggggtatc actacgcagg gtttgtaccc acagaaattg acgcaaaagg ctgtatgcga
     8521 aagatagatt taatttttga aaaagaagat taacttattt tagggagttg gttctaatga
     8581 taggacttaa aagacgagat atgaattata ttatgaaagt tggtgctaaa gctcaaggtg
     8641 tttctgtatc tgaatttagg gctatgctac aagataccat agacaaaact atggaaagta
     8701 cagacccaga cgtgcaggca aattttaaac gatactttgg aaataagcgc ccaacaccag
     8761 aggaatatat ttatacgatt accaaaaaga caaaggttaa ggtttaaatg ttgtaaaggg
     8821 ggcttgccgt atgaaacgct ttatgtacaa ttcagtatat tcaagcccaa tttaacagca
     8881 tactatttac aattaaatac gctataccag tagctcgtac aaaatttata ttttgtgcgg
     8941 gcttttttaa tacccgaaaa gtttttttaa ttattttcat ttttttggaa gcaaatcaca
     9001 ccttgctgta cagatatggt gcggaaagag ggataaacac ttttcaattc atagctggaa
     9061 aggaggtgag attatgaaac cgtctgactt ccaaaaaaca attcagtgtc agtttgaatg
     9121 taagctgaaa aaagttgtca aaggtattat ctggaactac cgtaaagaat taaaacgaag
     9181 aaaaaacaag gaaatatctt ttagcgaatt accagacatt acggtagaaa gtctggcaac
     9241 atgggacgac tacgaaacaa actacacaat ttttaatgtg tgtggcatag atattaaagt
     9301 ccttgatgat gaacttgcag aagctctcaa acagctaccc gaaaaaaaac gtaacaatgt
     9361 attgatgtat tacttcttgg aaatgagtga tacagagatt gcagatatta tgaattatac
     9421 cagaggggct gtgttcaaac acagacaccg tgcactagaa actatgaaag agatactaaa
     9481 ggagaagaaa tagaaatgaa gaaaaagtac aagcacccgt cttattattt gatttcatca
     9541 gctatggatg gggatgaaac tgcgattgag aaattactgg cattctatga cccgtacata
     9601 tcaaagtgtt gtttacgtcc tttatatgat gaatacggca atgtttatat tgttgttgat
     9661 atggaattaa agggacgtat tcgagaagcc ttaatcaaaa tgattttaga ctttgagatt
     9721 gatatagata tagaaaccga agaagaataa gcaaatacca gcagggcgtg attggttaaa
     9781 ttcccttctt tcctgccctg ctcctgcttt tatacatgga agcctacggc tttcgccgat
     9841 tgttctttga caactgaata aagcagacag atacgtttgt gatacagcga gccacgggga
     9901 ctgtacgcca tgacctttcc gacaagaaag cgagcgaccc acgcagttga tccgagagcg
     9961 acttgtggaa tggtcgtttt gccatgacct gctatcacag aataatgata cgtccgcatg
    10021 gtgcggttct gcccacaaga atgggaatag ttgagatact aacggagctt tccaaagccg
    10081 tctgtctgct tatgataaga cacacagaaa ggagttgttg caacatgaac aatactgatg
    10141 tgccgatttg ggaaaaatac acccttagta tagaagaagc gtcccgatat tttcgtatcg
    10201 gggaaaagaa gttgcgtaaa cttgccgagg aaaatctgga ctctggttgg gttatcgtta
    10261 atggaaaccg tattcagata aagcgaaaac agtttgaaaa aattattgat acactggacg
    10321 aaatctgatg tcttagagcc gtagatatgg tataatatta gtagcgtatc acggctcatt
    10381 ccatgacgga aaggagcttt acactatgtc aaaaatgaaa agacaagaca gtaaaggacg
    10441 caatttgcgt cttggagaga gccagagaaa agacggaaga tacgtttata aatataccga
    10501 tatattcggg aagccacagt ttgtatatgc ttggaaactt gtaccgacag acaaaacacc
    10561 tactggaaaa cgtgatgata aatcattgag ggaaaaagaa aagcagataa aaaaagacct
    10621 tgacgacggt atcgacacta tcggcggtaa aatgacagtc tgccagcttt atgcaaagaa
    10681 gaacaaccag aaaaagaaca tcaagagaaa cacggaaata ggacgacagt atcttatgaa
    10741 cgcactagaa aatgacccat taggtatgag ggcgattgat acagtcaaac agtccgacgc
    10801 taaagaatgg gctatcagaa tgaatgacaa aggttattcc tataagacaa tagataacta
    10861 taagcgttcc ttaaaggctt cattctatat ggcgatacaa gacgactgta tcagaaaaaa
    10921 tccttttcat ttcaagctaa gtgatgttct ggaagatgat acagagccta aagttatctt
    10981 gacaccagag caggaagaaa aacttctttc ctttatggaa acggataatg tttacagcaa
    11041 gtatcgtgat gaagttattc ttctgctgga aacgggactt cgtatctctg aattatgcgg
    11101 actgacaaca cacattgata tgcttaatcg tgtgattaac atagaccacc agctattacg
    11161 tgatacagag gtgggctact atatttccac acctaagaca aaaaacggca agcgagagct
    11221 tccattgaca gaaagagcat atcaggcact tgaacgaatt ttaaagaacc gaggaaaagc
    11281 tcaaccgctt gttgtagacg gttatagcaa tttcttgttc ttgaaccgtg agggcttgcc
    11341 aaaggtagca ggaaattatg aaagtatggt gcgtgggctg attaagaagt acaacaagac
    11401 ccatgaggac aagttgccga acatcacgcc ccactcattc agacatacct actgtacgaa
    11461 catggcaaat aagggaatga accctaacac cctgcaatac atcatgggac acgcaaacat
    11521 aaccatgaca ttagggtatt atgctcacgg tactttccag tctgcaaagg cagagttgga
    11581 aaggctggct tcttaatatc gaaaatgtat cttactactt atttactact tttggttgca
    11641 ttttcatgct ggtaaatgcc agcttatgcg aggtatcttc caaaaagaaa atgcccatac
    11701 agcccgaaaa tacgggatat atcggcattt accaacttat gaaaagataa tcagaaatta
    11761 gtaagttttt atatcaaaaa aatgattact gtaaagaaat cattttttat tataatcact
    11821 gatacatcaa atattctaaa taaaattttt atttatctgg aattgtatat tttttctata
    11881 atattaacta cagcgtacat tgcccaagca cagatagcca atacaaatac tcccatcatt
    11941 actaaatcta atttaaatac ttgagaacca tatactatca agtagcctat tccatatctt
    12001 gaaactaaaa attctccaac tattacacct acccatgcca taccaatatt aattttagtt
    12061 aaatttatta aatttcctgt gtttgcaggt aatatgagtt taaataatat ttgagattta
    12121 gtagctccaa aactttttaa catcttaatt ttttcttcat ctatattcat aaaataatta
    12181 taagctgaaa gtatagtaac aacaacagaa atcgttacag ctgttacgac gattccttct
    12241 attccagcac ctacccaaac tataattata ggagctaaag cagtcttagg aagagcattt
    12301 aaaactacca aaaatgggtc taatattttt gataattttt ctgaccacca aagagcaatt
    12361 gctaccaaaa tacctaatac agtacctata acaagaccaa gaacagtttc atatacagat
    12421 attccaatat gtttaaataa ttgaccacta aatgcatatt gaataaataa attgtaaata
    12481 tcacttggtt tgctaaatag aaatgtattt ataacattta agtcagctaa aagttcccag
    12541 attacaataa aaccaattaa aattaatagc tggtagaata atacatttct tttttctctt
    12601 tttacacctt taacatagtt tatatatcct tcagatcttt tattaagcct catgtgtatc
    12661 tagctccttc cataatatgt cgaaatactt ttgaaaatca ggaactttac gtgttttgag
    12721 aggcgttttt gttccatcca tgttaagttc aatatcgtaa atatttttta tggtagctgg
    12781 tcttttagat agtattgcaa ccttatctga tatgcttatt gcttctgcta tagctaaaaa
    12841 agtgcaacta attgcttaaa gaaacagaat tatcaacttc agcacccata taaacaatat
    12901 taagatttcc taaactgcta tcccaaacga tactattaat aatagtagat aataacaatc
    12961 tcttatcatc taaactggca ttatcaactt catcattaaa tctcttcaaa ttactaacaa
    13021 taatatcaat attaatactg tcactactaa tattgatgtt actagattcc aaaatattaa
    13081 tcttatcctt taaaatacta atctcattat ttaggctctc aatctgggaa actatataat
    13141 cagaagcagt actaccagta ttttttgcaa gctctataac taaattttta ataagtcttt
    13201 ccttatctaa aatttgattt ttaagtaaat tagtctcaga tttaaaaata ttaaaaacat
    13261 tatcagtctt aatgttatta ctattgaatg cacttataat agactcttct ttacaattct
    13321 taattttatc tataactaaa ctttcaacta atggaccatt aagattttta cagttgcaac
    13381 tatcagaccc aagtgttttt ttagtaccac aaatataata atactttaaa tccttgtcag
    13441 tttttttgcc tttataggta attctcatat tagaaccaca tttaccacat tttataagac
    13501 cagataaaag agcagttttt ccagttgata tccttggagt tttatcacga tttttatcta
    13561 attgattttg tacttcaagc catatttcag gttctatgac tccatggtgt tttgcaattg
    13621 ctgctattga gttagatgta tttttagcat aggtaaggat tccacatttt ctatctggag
    13681 tacctacaac atccatacca ctatttttaa ggtaatctaa aatttcatca ttagctttta
    13741 catatgctgg atttctaagt attctagata aagaactagg gtcaaatttg ccaccacgag
    13801 gaccccttat tccattatta tagacatatt tatataactt agataaggac ctaagttcta
    13861 aatatttatt gtatattagc tttacaatct ccatttgttc atcatttact tgaagcttat
    13921 acatacttct ttcttttaga ttttcatcta agaatgtgat tttttcactg ttgaatccat
    13981 gaggtgtatt gcctccaagc catctaccac tacgggctaa ttcatacata ttgtctttta
    14041 tacgttctgc tattgtttct ctttctaatt gagcaaatac acttgatata aacatcatag
    14101 ctcttcccat tggagttgaa gtatcaaatt gttctttgat agatataaat gatatgctta
    14161 gttcatttaa tttttctatt aaagtagaga agtcagatac atttctcgat atcctatcta
    14221 atctataaca aactaggtaa ctaaatttct tatctttggc atcctgcatc attttcttaa
    14281 attgtggtct atctatattg ctaccactaa atccctcatc ttcatatatc aaaaaatctt
    14341 ttacaccaat agactttgca taatcaatac ataattgtat ttgattttct atagaatcac
    14401 cttttccagt aaatcttgat tttcttgaat aaattgcagc tttcaaaatt aaaaccccct
    14461 ataagttagg atatatattt gaaactattt atctacaacc ttttaagtaa acttattaga
    14521 atgaatttat taattaggta aatttatata attctacttt ttataatata tga
//
LOCUS       DAEPKC010000102        14365 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.102, whole genome shotgun sequence.
ACCESSION   DAEPKC010000102 DAEPKC010000000
VERSION     DAEPKC010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14365)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14365)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14365
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.102"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            265..1278
                     /gene="aroF"
                     /locus_tag="KR294_003082"
     CDS             265..1278
                     /gene="aroF"
                     /locus_tag="KR294_003082"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003452924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HBH0241141.1"
                     /translation="MIVVLKMGADKNEVKKLIEAIGREGVEVNPIDGTELTVLGLVGD
                     TSKIDAKRIEANKVVEKVMHVVEPFKKANRKFHPEPSIINVNGMEIGSKKIAMIAGPC
                     SVETEDQIVSIAKDVKKSGAGFLRGGAFKPRTSPYAFQGLKYDGLDLLKKAKEKTGLP
                     IVTEIMSTQDIDIFEENVDVIQVGARNMQNFDLLKELGKTNKTILLKRGLSATIEEWL
                     MSAEYIMAGGNENVVLCERGIRTFETYTRNTLDLSAILAVKKLSHLPVIVDPSHAAGK
                     SWMVDSLSKAAIAVGADGLIIEVHNDPAHALCDGKQSIKPNEYDELISELKTIASAVG
                     REI"
     gene            1300..2364
                     /locus_tag="KR294_003083"
     CDS             1300..2364
                     /locus_tag="KR294_003083"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HBH0241142.1"
                     /translation="MEEKLLVNLKENSYNIFIKKNILKNIGEEIKKIYFGNKIFIVTD
                     ENIAKLYLDKVKNNLSESGFEIKSLILKSGEETKSFNTLPKIYDSLLDFKLTRKDLII
                     TLGGGVIGDLGGFAAATFLRGISFIQIPTSLLAQVDSSVGGKVGVDLERGKNLVGSFY
                     QPKAVFIDPNVLLSLPEKFYRDGMAEVIKYGCIKDKTFFNKLLSLKNREEVMQHIEYI
                     IHKCCFIKKTVVEADEKDFGDRMLLNFGHTLGHAIEKYYNFTGYTHGEAVAIGMYKIT
                     LESEKIGITKKGTSELIKSILMNYNLPYEIELRDNKSIVDAISLDKKNLGDTLKIILL
                     KDIGESIIYNTTSKFFQEVR"
     gene            2364..3677
                     /gene="aroA"
                     /locus_tag="KR294_003084"
     CDS             2364..3677
                     /gene="aroA"
                     /locus_tag="KR294_003084"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HBH0241143.1"
                     /translation="MGSLKIYPSKLSGDVKIPPSKSMAHRAVICSSLSNGKSRISNID
                     FSDDIIATIRAMTSLGAIIEKKEDILEISGIFSKEGILNRENQLNQPKLTIDCNESGS
                     TLRFLVPISLAFDGVKRFIGRGNLGKRPLDTYYEIFDRQNIKYSYKENQLDLIISGKL
                     KPDEFRVKGNISSQFITGLLFILPTLESDSKIIITTELESKGYLDLTLSTIKDFGVEI
                     INNNYKEFIIKGNQTYKARDYKVEGDYSQGAFYLSADAIGEDISILDLKEDSLQGDSE
                     VVEILSRMGMEILREGNKIKGITNGLNGTLIDASQCPDIIPVLSVVASLSIGRTTIIN
                     AGRLRIKECDRLHAINVELNKLGANIEEKEDSLIIEGVSKLNGGVEVWSHKDHRIAMT
                     LAIASCRCDKPIILKDFECVSKSYPHFFKDFKMLGGRIDEWNMGK"
     gene            3655..4734
                     /gene="aroC"
                     /locus_tag="KR294_003085"
     CDS             3655..4734
                     /gene="aroC"
                     /locus_tag="KR294_003085"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HBH0241144.1"
                     /translation="MSGIWGNNLKVSIFGESHGNAIGINIDGLPSGIELDLDNIDKEM
                     KRRAPGKNSISTSRNESDIPEILSGYFNGRTTGTPLCAIIRNSDTRSKDYGELKNLMR
                     PGHADFTGNVRYSGFNDYRGGGHFSGRITAPLVFCGAICKQILSQKGIEIGAHIKKIK
                     NIEDMSFDYVNISKQQLSNLQTLELPLLDLSKEEAMKNTIIDAKNQGDSVGGIIECAV
                     VGINVGLGNPFFDSVESTLSHLLFSVPAVKGVEFGLGFELADMYGSQSNDEMYYEGNQ
                     VKSKTNNNGGIIGGITTGMPIIFKVAIKPTPSISRQQNTVNIKDKKDDILYIKGRHDP
                     CIVQRAIPVIEAVTAIGIFDLMKGR"
     gene            4737..5933
                     /gene="pheA"
                     /locus_tag="KR294_003086"
     CDS             4737..5933
                     /gene="pheA"
                     /locus_tag="KR294_003086"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HBH0241145.1"
                     /translation="MEDLTRYRNEIDNIDKELIQLFEKRMNTVLEIARHKMKNNTTIL
                     QKDREEKVLSRAVDNLDNKAYSQETVQFFNSIMEISRGLQKRFIDNDGEQKIEFSLDS
                     SNKNFDLSNVNKYKSLKDELNKKNILVGFPGKSGSFTEEALNKFFNKKISKKQFKEFE
                     DVFIALKNKEINYGIIPIENSSTGAISETYDLLRKYGFYIVGEECIKIDQNLIGIKDT
                     KLEDIKEIYSHPQGIGQCSEFLKQNSTWKLIPFNNTATSAELVRKLQDKTKAAIASKK
                     AASIYGLEIISPCINDIANNYTRFVVISNQIHIEEESNKMSVVFSVEHEAGKLYKVLG
                     YFAKNNINMTKIESRPMKNASWRYFFYIDFECSIYNAKVYDLLELIEHNTAYFKFMGV
                     YKNKTE"
     gene            5980..6789
                     /gene="aroE"
                     /locus_tag="KR294_003087"
     CDS             5980..6789
                     /gene="aroE"
                     /locus_tag="KR294_003087"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HBH0241146.1"
                     /translation="MNFFGLVGEKLSHSVSPQIHKRVFEILNIESAYKNFEISKEDIS
                     KLDGAIKLLGIQGVNVTVPYKERIMKYLDFISPEAKRIGAVNTILLRENMLYGYNTDY
                     FGLDSMFKMANIDVQGKVAVILGTGGASKAALTYFIDSGIEKLYVSTRKKDDKKLLNS
                     KAILIDYEELKHIKGDIILNATPVGMYPNVGISPVSKSIIQNFDILIDLIYNPGETEF
                     LRIGNSMGKKTCDGLYMLVGQAIKSQEIWQDTKIDNSILDVIYNELKLEFL"
     gene            6801..7334
                     /locus_tag="KR294_003088"
     CDS             6801..7334
                     /locus_tag="KR294_003088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HBH0241147.1"
                     /translation="MINKTKEKLILIGMPGSGKTTIGKLLAKEYNCSFCDMDDYIIQI
                     SQKSIAELFSEGEDIFRNYETQACRELSISDKTVISTGGGVIKKDINMEILKETGIII
                     FIDRPIQKILEDININSRPLLKNGKDRLYNLYNERINLYKKFSDIEILNDKSLNNAVY
                     NITNAVSENFKFDFKEK"
     gene            7355..8194
                     /locus_tag="KR294_003089"
     CDS             7355..8194
                     /locus_tag="KR294_003089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HBH0241148.1"
                     /translation="MNIVIVGLGVIGGSFAKALKKAGYENVFGVDVDLETLKKAEKAK
                     IIKKGCTTGKELFKKADLIILSIYPRLVVDFLNNNKNFFKKGTIITDTTGIKETLIND
                     VLQIIPDDIDFIFGHPMAGREKKGIDFASEQVFNGANYIITPTGRNNIKNLELVENLI
                     LEIGFKRVKKLTSQKHDEIIAFTSQLPHVMAVALINSDEEGRDTGKFIGDSYRDLTRI
                     ANMNEDLWSELFLGNRDNLLKVIENFESEVNLVKEAIFNNDKNKLIEYFKKSSIRREA
                     LEK"
     gene            8462..9943
                     /locus_tag="KR294_003090"
     CDS             8462..9943
                     /locus_tag="KR294_003090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HBH0241149.1"
                     /translation="MKKNRLIAKNISIAFIVLFFFSVFTFFYVGNINRVLEYETNDII
                     TVTIAGWIILSFLFLGIIIYILYSKANSQKTIEKVAYTDFVTGYSNWRKFELDVTNLL
                     KKTSQNNKYAMVIFDIDKFKAINDIYGHKKGNLILKDIADTLNELTDINETFARVSAD
                     NFNILLTYNKKEDIINIIKKIMANNELVNLSFGIYEIKDKDLSVSVYSDRASLAKSSI
                     KNNSDVNFAFFNDKLREKLLFEDKIEKEMEYALESGQFVMYLQPKYNIKLDKFCGSEA
                     LVRWQYTEKEVIYPGDFIPIFEKNGFIRKIDMYILEQACKEIRSLFDKGISPLPISVN
                     FSRVDFFKKDFIENIVNICDRYKIPYSLIEIEITESSMFGDTDTLFNVSRNLQDIGFI
                     VAMDDFGSGYSSVNMLKNIPLNVIKLDRGFFVYDKDVDKSQIVIKSIVSLIKQLGIRV
                     VAEGIETRSQIEMLKKANCDIVQGYYFSKPLPIKEFEKLVYKI"
     gene            9976..13413
                     /locus_tag="KR294_003091"
     CDS             9976..13413
                     /locus_tag="KR294_003091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing protein"
                     /protein_id="HBH0241150.1"
                     /translation="MIRAKSLKNVLSIVLIFLFTIISFSDFAFKTNVQEEENSKINLR
                     EISLQSSNAIKIKLDSSLSFIKSVANMVSYFNTIDNSKIVPLLANISKESDFQRISIV
                     SPDGISHTSDGKIINVSKYQYFKKAIKGESNISEVVKSPIDGKDTFVIATPVFNKNNK
                     IIGVLYGSYYNDKLAEFIDITSFNSEGYIDIFESSGQFVLKSSHTNKLIKSSSNIYDI
                     FKKASFDDGYSYKKIYEDTKNNKSGFTSYEYKGENRYATYTPIGVNDWYVISVIPQYT
                     VRRNIDKINQLAFSLIFKVFLLFIMLITYIIYKNNKSQKDILKANKEISSITNSIPGG
                     VQKCTLGETCNINFLSDGFIELFGYTREEIKTLFNNDFYSLIHKDDVERIKKEIFKQL
                     YKNKTVELEYRIITKNGNTVWVLDKGELITEPDGKEYFCCVTVDITRTKQLEQEMEQK
                     NLELEMISENVLGGIIITEFNDDFTIKYANSGYLSMIGYTREQLENELKYKACNLVFY
                     EDRKKALESIQHQLNTKGIAVYQHRIRRRDGNIIWVSIKGRLIVDDDGIEKGIWILND
                     ITDLKNAEQKLKINEERFRIALKQTSNTIFEYDIKTKSLLNTSKELDKYNIYKITKNV
                     PYSLVELGVIHKDFSDDFINMYENVINGAKKASCVVKMKLPDENYIWNKVTLTTIFDE
                     DGNPVRAIGIQEDISKQKEAEIRYNQEGKYHSAILSEAMITYEINVSKDTFIKGNESW
                     QKPFGIKPDNNYSQMVKTIANSIVHKDNKETFLNTFLCENLLDAYKNNVTEIKLEYRR
                     MNQENKMIWVICTMHLIKDSITNDIKALAYVKDIDKQKNEEIRLKLKAERDTLTGLYN
                     KGTTEKLINDFLNSEEASLGMHAFLIVDIDNFKSVNDNLGHVFGDKVLFEVSKNLKPI
                     FRKDDIVGRIGGDEFIVFLKNIQSFENIKKKAEKICDIFRNSYTENKKTYKISGTVGI
                     SFVPEHGTVFEELYKKADIALYYAKSKGKDKYALYNDCIYQNELENNISDNNIKLADK
                     CEKSKPVLKEILDSIDNYIYIVNPNTYELLFVNNKVSRLDLEIKLGETCYKSLLKSDR
                     PCNNCPLNGLEENKHSKFKIETNTFGKNISIASWINCIDGEYNCLIECIDSSLYKNK"
     gene            13431..14177
                     /locus_tag="KR294_003092"
     CDS             13431..14177
                     /locus_tag="KR294_003092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HBH0241151.1"
                     /translation="MLNSITLILGIIFTIYYFYLKIVFGGISFSEIFLVVGIVLIIYQ
                     IFKKKIKEKKVFYRVLKIIISIFLIVFVVTESLIIFYPKNSLESKSDYLLILGASVKK
                     TTPSTTLKGRLDTALKYLKINDNCYVVVSGGKGSGEKITEAKAMKDYLIKNGIDKNRI
                     IEEDKSTNTYENFKYSKLKIEEHSQRKLSDLKVKIVTTDFHVLRSKILAYRNGYKNTS
                     FYASKSKLSFVPTYYTREFFALWKTIIFDR"
BASE COUNT         5926 a         1428 c         2426 g         4585 t
ORIGIN      
        1 ctaacagcaa aactttatag ctttttttac tttatgttct ggggctttta ttttagcgct
       61 ggctatttct tttacaaaaa tatatgtact tcctttctgg tgaggcctta ttttagtgat
      121 tttgagcata agtaaatttt ataaaaatga ttattttata tatttatata agatttagtg
      181 cttgatagat tattttagag aactcattag tgagttctct tttttatttt aaatataaaa
      241 ttataatatt gggaggtagt aaaaatgata gtagtattaa aaatgggagc agataaaaat
      301 gaagttaaaa aattaattga ggctattggg agagaaggag tagaagttaa tcccatagat
      361 ggaacagaat taactgtttt aggtttagtt ggagatacta gtaaaataga tgccaaaaga
      421 atagaagcaa ataaggtagt tgaaaaagtt atgcatgtgg tagagccttt taaaaaggcc
      481 aatagaaaat ttcatccaga accttcaatc ataaatgtta atggaatgga aattggttca
      541 aagaaaattg ctatgatagc tgggccttgt tctgttgaaa cagaagacca aatagtatct
      601 atagctaaag atgtgaaaaa atcaggtgca ggatttttga gaggtggagc attcaaacca
      661 agaacatcac catacgcttt ccaaggattg aaatatgatg gattggattt attaaaaaaa
      721 gcaaaagaaa aaacagggct tcctatagtt acagaaataa tgtcaacaca agatatagat
      781 atatttgaag aaaatgtaga tgtaattcaa gttggagcta gaaacatgca aaactttgat
      841 ttattaaaag aattaggtaa aacaaataaa acaatacttt taaaaagagg attatctgct
      901 acaattgaag agtggctaat gtcagcagag tatataatgg ctggaggaaa tgaaaatgta
      961 gttctttgtg aaagaggtat aagaactttt gaaacatata ctagaaatac tttggattta
     1021 agtgcaattt tagctgtgaa gaaacttagt catttaccag ttatagttga cccaagtcat
     1081 gcagcaggta aatcatggat ggttgactct ttatctaagg cagcaattgc agttggagca
     1141 gatggtctaa taatcgaagt tcataatgac ccagcacatg cactttgtga tggaaaacaa
     1201 tcgattaagc caaatgaata tgatgaattg ataagtgaat taaagactat cgcatcagca
     1261 gttggtagag aaatataatc tataaaagga tggttaaacg tggaagaaaa actattagta
     1321 aatttaaaag aaaatagcta caatatattt attaaaaaaa atatactaaa gaatatagga
     1381 gaagaaataa aaaaaatata ttttggaaat aagattttta ttgtaactga tgaaaatata
     1441 gcaaaattat acttggataa agtaaaaaat aatttaagtg aatctggatt tgaaattaaa
     1501 tctttaatat taaaatctgg tgaagaaaca aaatcattta atactcttcc taaaatatac
     1561 gatagtttac ttgactttaa gttaactaga aaagatttga ttattacttt aggaggaggg
     1621 gtaataggtg atttaggtgg atttgcagca gcaacttttt taagaggtat aagttttatt
     1681 caaattccaa catctttatt agcacaagtt gatagttctg taggtggaaa agttggagtt
     1741 gaccttgaga gaggcaaaaa cttagtggga agcttttacc aaccaaaggc tgtgtttatc
     1801 gacccaaatg tattattatc acttccagaa aaattctata gagatggaat ggcagaagtt
     1861 ataaaatatg gatgtataaa agacaaaact tttttcaata aacttttaag tttaaaaaat
     1921 agagaagaag taatgcaaca tatagaatac attatacata aatgttgctt tattaaaaaa
     1981 actgtagttg aagctgatga aaaagacttt ggagatagaa tgcttctaaa ctttggccat
     2041 acattaggtc atgctattga gaaatactac aattttacgg gttataccca tggagaagct
     2101 gttgccatag gaatgtataa gataacttta gaaagtgaaa agataggaat tacaaaaaaa
     2161 gggacatcag aacttataaa atcaatttta atgaattata atttgcctta tgagattgaa
     2221 ttaagagata ataaatctat agtagatgct atatctcttg ataaaaaaaa tctaggtgat
     2281 acattaaaaa taatactttt aaaagatatt ggagagagta ttatatataa tactacttct
     2341 aaattttttc aggaggtaag ataatgggaa gtctaaaaat atatccaagt aaattatctg
     2401 gagatgtaaa aataccacca tcaaaaagta tggcacatag ggcagttatt tgttcatctc
     2461 taagcaatgg aaaaagtaga atttctaata tagatttttc tgatgatata atagctacta
     2521 taagagcaat gacatcatta ggagctatta tagaaaagaa agaagatatt ttagaaattt
     2581 cgggaatttt ttctaaagaa ggtattttaa atagagagaa tcagttgaat caacctaaat
     2641 tgacaataga ttgtaatgaa tcaggctcta cattgagatt tttagtacct atatctttag
     2701 catttgatgg tgtaaaaagg tttataggta gaggaaatct tggaaaaaga ccacttgata
     2761 cttattatga gatatttgac agacagaata taaaatatag ttacaaagaa aatcagttag
     2821 atttgattat atcaggtaag cttaaaccag atgaatttag agtaaaagga aatataagtt
     2881 ctcagtttat cacaggttta ctgtttatat tgcctacgct agagagtgat tcaaagataa
     2941 taattactac tgagctagaa tctaaaggat atttagattt aactctttca acgataaaag
     3001 attttggggt agaaattata aacaataact ataaagaatt tattataaaa ggaaatcaaa
     3061 cgtataaagc gagagattat aaagtagaag gagattattc tcaaggagca ttttatttat
     3121 cagcagatgc tataggagaa gatattagca tattagacct taaagaagat tctcttcaag
     3181 gggatagtga agtagttgaa attttatcta ggatgggaat ggaaatatta agagaaggca
     3241 acaaaataaa aggaataaca aatggtttaa atggtacttt gatagatgca tctcaatgcc
     3301 cagatataat acctgtatta tctgtagtag catccttaag tatagggagg actacaataa
     3361 ttaatgctgg taggcttaga attaaagaat gtgatagact tcatgcaata aatgttgagt
     3421 taaataaact tggagcaaat atagaggaga aagaggatag tttgataatc gaaggagtaa
     3481 gcaagttaaa tggtggagta gaggtgtgga gtcacaaaga ccatagaatt gctatgacac
     3541 ttgcaattgc ttcttgtaga tgtgataaac caataatatt aaaagatttt gagtgtgtat
     3601 caaaatctta tccacatttt tttaaagatt ttaagatgtt aggaggtcga attgatgagt
     3661 ggaatatggg gaaataattt aaaagtatca atttttggag aatctcatgg aaatgctata
     3721 ggtataaata tagatggtct tccttcgggg attgaacttg accttgataa tattgataaa
     3781 gaaatgaaga gaagagcacc tggaaaaaat tctatatcta cttcaagaaa tgaaagtgat
     3841 ataccagaaa ttctaagtgg atattttaat ggaagaacta caggaacgcc attatgtgca
     3901 atcataagaa atagtgatac tcgttcaaaa gattatggag agcttaaaaa cttaatgaga
     3961 ccaggacatg cagatttcac aggtaatgtg agatattctg gatttaatga ctatagaggt
     4021 ggaggtcatt tttcaggtag gataacagct ccattagtat tttgtggggc tatatgtaaa
     4081 caaattttat cacaaaaagg aatagagata ggagcacaca taaaaaaaat taaaaatata
     4141 gaagatatga gttttgatta tgtaaatatt tcaaaacaac agttatcaaa tttgcaaact
     4201 ttggaactac ctttacttga tttatcaaag gaagaagcca tgaaaaatac gattatagat
     4261 gcaaaaaatc aaggagattc agttggtggt ataattgagt gtgcagtagt aggtattaat
     4321 gtagggcttg gaaatccatt ttttgactct gttgaatcta ctttatcaca tttattgttt
     4381 tctgttcctg ctgtaaaagg tgtagagttt ggtttaggtt ttgaacttgc agatatgtat
     4441 ggctctcaaa gtaatgatga aatgtattat gaaggaaatc aagttaagag caaaacaaat
     4501 aacaatggag gaattatagg agggattact actggaatgc caataatttt caaagtggca
     4561 attaagccaa ctccatcaat tagcagacaa caaaacacag ttaatataaa agataaaaag
     4621 gacgatattt tatatattaa aggcagacat gacccttgta tagttcaaag ggctatacct
     4681 gtaatagaag cagtaacagc cattggaatt tttgatttga tgaaaggacg ataataatgg
     4741 aggatttaac gagatataga aatgagattg acaatataga taaagagctt attcaattat
     4801 ttgaaaagag aatgaataca gttcttgaaa ttgccagaca taaaatgaaa aataacacta
     4861 ctatacttca aaaagataga gaagaaaaag tactaagtag agccgtagat aatttagata
     4921 ataaagcata ttcacaagaa acggtacagt tttttaattc tataatggaa attagtagag
     4981 gattacaaaa aagatttata gataatgatg gtgagcagaa aatcgagttt agtttagatt
     5041 catcaaataa gaattttgat ttgtcaaatg taaataaata taagtcttta aaagatgaat
     5101 taaataaaaa aaatatccta gtaggctttc ctggaaaatc aggttcattt acagaagaag
     5161 cactaaataa attcttcaac aaaaaaatat caaaaaaaca atttaaagaa tttgaagatg
     5221 ttttcatagc acttaaaaat aaagaaataa actatggaat aatccccata gaaaattcat
     5281 ctacaggagc tatctctgaa acttatgacc ttttgagaaa gtacggtttt tatatagttg
     5341 gagaagaatg tataaaaata gaccaaaatt taatagggat aaaagacaca aagcttgaag
     5401 atataaaaga aatatattct catccacaag gtataggaca atgtagtgaa tttttaaaac
     5461 aaaatagtac atggaaattg atacccttta ataacacagc aacaagtgca gaacttgtaa
     5521 gaaaacttca agataaaaca aaagcagcaa ttgcaagcaa aaaagctgca agtatttatg
     5581 gattagaaat aataagtcct tgtataaatg atatagcaaa caactataca agatttgtag
     5641 taatcagtaa tcaaatacac attgaagaag aatcaaacaa aatgagtgta gtattttctg
     5701 ttgaacatga agcaggaaaa ctttataaag tacttggata ctttgctaaa aataatataa
     5761 atatgacaaa aatagaatca agacctatga aaaatgcctc atggagatat ttcttttata
     5821 tagattttga gtgttctata tacaatgcta aagtgtacga tttattagaa ttgatagaac
     5881 ataatacagc atattttaaa tttatgggag tatataaaaa taaaactgaa tagataagat
     5941 aaatttttat ttaatttata attattagga ggtgtaagta tgaatttttt cggtctagta
     6001 ggtgaaaaac tctctcacag tgtttcacct caaatccaca agagagtatt cgagatattg
     6061 aatattgaaa gtgcttataa aaactttgaa atttcaaaag aagatatatc taagctagac
     6121 ggtgctataa aattattagg aatacaaggg gtaaatgtta ctgtaccata taaggagcgt
     6181 attatgaaat atcttgattt tatatcacca gaggcaaaac gtataggagc agttaataca
     6241 attttactca gagaaaatat gttatatggt tacaatacag attactttgg tcttgatagt
     6301 atgtttaaaa tggctaatat tgatgttcaa ggaaaagtag cagttatatt aggaactgga
     6361 ggtgcttcta aagctgctct tacatatttt attgattctg gtatagaaaa gctttatgtt
     6421 tcaactagaa aaaaggatga taaaaaatta ttaaatagta aagctatatt aatagattat
     6481 gaagaactta aacatataaa aggagatata atattaaatg ctacaccagt aggtatgtac
     6541 cctaatgtag gaatttcacc agtgtcaaaa tctattatac aaaattttga tatattaata
     6601 gatttaattt acaatcctgg agaaacagag tttttaagaa ttggtaatag tatgggtaaa
     6661 aaaacttgtg atggattata tatgctggtg gggcaagcaa taaaatctca ggaaatttgg
     6721 caagatacta aaatagataa tagtatttta gatgttatat ataatgaact aaaattagaa
     6781 tttttgtaag ggagattgtt atgataaata aaacaaaaga aaaattgata ttaataggta
     6841 tgccaggtag tggaaaaact acaattggta aacttttggc caaagaatat aattgtagtt
     6901 tctgtgatat ggatgattat ataattcaaa tatctcaaaa aagtatagca gagttgtttt
     6961 cagaaggaga agatatcttt aggaactatg agactcaagc atgtagagaa ctttctataa
     7021 gtgataaaac agtgatatct acaggtggag gtgtaataaa aaaggatatt aatatggaaa
     7081 tactaaaaga aacaggtata ataattttta ttgatagacc tatacaaaag attttggaag
     7141 atataaatat taattcaaga ccattattaa aaaacggaaa agatagattg tataatcttt
     7201 acaatgagag aataaatctt tataaaaaat tttcagatat agagatttta aatgataaat
     7261 cattaaataa tgctgtatat aatattacaa atgcagtcag tgaaaatttt aaatttgact
     7321 ttaaagaaaa ataatctagg gggaaataaa aataatgaat attgttattg taggactagg
     7381 agttatagga ggctcttttg ctaaagcatt aaaaaaagct ggatatgaaa atgtatttgg
     7441 agtagatgta gatttagaaa ctttaaaaaa agcagaaaaa gcaaaaatca taaaaaaagg
     7501 atgtactaca ggtaaagagt tatttaaaaa agctgattta attatattat ctatatatcc
     7561 tagattagtt gtagattttc taaataataa taaaaacttt tttaaaaaag ggactataat
     7621 tactgatact acaggaataa aagaaacact tatcaatgat gtgttgcaaa ttattccaga
     7681 tgatatagat tttatatttg gacatccaat ggcaggtagg gaaaaaaagg gtattgattt
     7741 tgcaagtgaa caagttttta atggcgcaaa ttatataatt actccaactg gcagaaacaa
     7801 cataaaaaat ttagagttag ttgaaaattt aattttagag attggattta aaagagtaaa
     7861 aaagttaact tcacaaaaac atgatgagat tatagctttt acttctcagt tacctcatgt
     7921 tatggcagtt gctcttataa atagtgatga agaaggtaga gatacgggta aatttattgg
     7981 agatagttat agagatttaa ctagaattgc aaatatgaat gaagacttat ggagtgaact
     8041 ttttttagga aatagagata atttactaaa agttatagaa aactttgaat cagaagtaaa
     8101 tttagtaaaa gaagctatat ttaacaatga taaaaataaa ttaatagagt attttaaaaa
     8161 atcatcaata agaagagaag ctttagaaaa ataaatatta atatttaagc tatatataga
     8221 tgggtataaa tataagcgat agtgtattta attgtattaa taaatatgga ttcaatataa
     8281 ttaaatatgc tattgatata tttgtaccct taactattgt tatcttttag atgataatga
     8341 tatttattta aatactcttt attaacaatt tataaaactt aattgtaaaa aatacttatt
     8401 aatagtaaaa taaagtgaat caattatatt ataattgcta aagagagtga ggtgtagcta
     8461 tttgaaaaaa aatagattaa tagcaaagaa tatatcaata gcatttatag tactattctt
     8521 ttttagtgta tttacattct tttatgtagg taatattaat agagtgttag aatatgaaac
     8581 aaatgacata ataacagtta caattgctgg atggattata ctttcatttt tatttttagg
     8641 tattataatt tacatattat attcaaaagc aaatagtcaa aaaactatag aaaaagtagc
     8701 atatacggat tttgtaacag gttattccaa ctggagaaag tttgaattag atgttacaaa
     8761 tttattaaag aaaacatcac aaaataataa atatgcaatg gtcatattcg atattgataa
     8821 atttaaagca attaatgata tatatggcca taaaaaggga aatttaatat taaaagatat
     8881 tgcagatact ttaaatgaat tgactgatat caatgaaact tttgctcgtg taagtgctga
     8941 taatttcaat atattattaa catataacaa aaaagaggat ataataaata ttatcaaaaa
     9001 gattatggca aataatgaac ttgtaaactt atcttttgga atttatgaaa tcaaagataa
     9061 ggatttatct gtaagtgtat atagtgatag agcttcactt gcaaaatcat caataaaaaa
     9121 taatagtgat gtaaattttg cattttttaa tgacaaatta agagagaaat tattatttga
     9181 agataagata gaaaaagaaa tggaatatgc tcttgaaagt gggcaattcg taatgtattt
     9241 acaaccaaaa tacaatatta aattagataa attttgtgga agtgaagccc tagtcagatg
     9301 gcaatataca gaaaaagagg tcatatatcc aggtgatttt attcctatat ttgaaaaaaa
     9361 tggatttatt agaaagattg atatgtacat attagaacaa gcttgtaaag aaatccggtc
     9421 tttatttgat aaaggaattt cacctttacc tatatctgta aacttctcaa gagttgattt
     9481 ttttaaaaaa gattttattg aaaacatagt aaatatatgt gatagatata aaataccata
     9541 tagtttaata gaaattgaaa ttactgaatc tagtatgttt ggagatactg atactctatt
     9601 taatgttagt agaaacctac aggatattgg ctttatagtt gcaatggatg attttggctc
     9661 tggatattct tctgtaaata tgcttaaaaa tataccatta aatgtaataa aattagatag
     9721 aggatttttt gtttatgata aagatgttga taagagtcaa attgttataa aaagcatagt
     9781 ttctctcatt aagcaattag gaataagggt tgttgctgaa ggaattgaaa caagaagtca
     9841 aatagaaatg ttaaaaaaag caaattgtga tattgttcaa ggatattatt tttcaaaacc
     9901 attaccaatt aaagaatttg aaaaattagt ctataaaata tagtcagcga gtcttaaatg
     9961 ggaggtggtg attaagtgat aagagcaaaa tcgttaaaaa atgtactgag tattgtttta
    10021 atatttttat ttacaataat ttctttttct gattttgcat ttaaaactaa tgtccaggaa
    10081 gaagaaaata gtaaaattaa tttaagagaa atatccctac aaagttccaa tgctataaaa
    10141 ataaaattag atagttctct atcctttatt aaaagtgtgg caaatatggt ttcttatttt
    10201 aatactatag ataactcaaa aatagttcca ttattagcta atatatcaaa agaatctgac
    10261 tttcaaagaa tctctattgt atctcctgat ggaataagtc ataccagtga tggcaaaatt
    10321 atcaatgtgt caaagtatca gtattttaag aaagctatta aaggagaaag taatatatct
    10381 gaagttgtga aatctccaat tgatggaaaa gatacttttg ttatagctac tcctgtattt
    10441 aataagaata acaaaataat tggtgtttta tacggttctt actacaatga taaattagct
    10501 gaatttatag atataacaag ttttaatagt gaagggtaca tagatatatt tgaatctagt
    10561 ggtcaatttg ttttaaaatc ttcacataca aacaaactga ttaagtcaag tagtaacata
    10621 tatgatatat ttaaaaaagc ttcttttgat gatggttata gctataaaaa aatatatgaa
    10681 gatacaaaaa ataacaagag tggctttacc tcatatgaat acaaaggaga aaatcgttat
    10741 gctacttata cacccattgg tgtaaatgac tggtatgtaa tttctgtgat accacaatat
    10801 actgtaagaa gaaacattga taaaataaat caattagcat tttctcttat tttcaaggta
    10861 ttcttattgt ttattatgct tataacatat attatttata aaaacaataa atctcagaaa
    10921 gatatactaa aagctaacaa agaaatctca tctattacaa atagcattcc tggaggagta
    10981 caaaagtgta ccctgggtga aacatgcaat attaattttt taagtgatgg atttatagag
    11041 ttgtttggtt atacaagaga agaaataaaa acattgttta ataatgattt ttatagttta
    11101 atacataaag atgatgttga aagaataaaa aaagaaattt ttaaacaact ttacaaaaat
    11161 aaaactgttg aattagaata taggattata acaaaaaatg gtaatacagt atgggtttta
    11221 gataaagggg agcttataac agaacctgat ggaaaagaat atttttgttg tgtaactgta
    11281 gatattacta gaacaaaaca attagaacaa gagatggaac aaaaaaatct agaacttgaa
    11341 atgatatcag aaaatgtttt aggtggtata attataacag aatttaatga tgattttact
    11401 ataaaatacg ctaactctgg ttatctttca atgattggat atacacgtga acaattagaa
    11461 aatgaactta aatacaaagc ttgtaatctt gttttttatg aagatagaaa gaaggctctt
    11521 gaaagtatac aacatcaatt aaacacaaaa ggaatagctg tatatcaaca tagaataaga
    11581 agaagagatg gtaatattat ttgggtttct ataaaaggaa ggcttattgt tgatgatgat
    11641 ggtattgaaa aaggtatttg gattctaaat gatataacag atttaaaaaa tgcagaacaa
    11701 aaacttaaaa taaatgaaga aagatttaga attgcattaa agcaaacatc aaacactata
    11761 tttgagtatg atataaaaac aaagtcactt ttaaatacta gtaaagagct tgataaatat
    11821 aatatttata aaattactaa aaatgttcca tattctctag tagaattagg agttattcat
    11881 aaagatttta gtgatgattt tataaatatg tatgaaaatg taataaatgg agcaaaaaaa
    11941 gcaagttgtg tagttaagat gaaacttcca gatgaaaatt atatatggaa taaagttacc
    12001 ttgactacga tttttgatga agatggtaat cctgtaagag caattggtat acaggaagat
    12061 ataagcaaac aaaaggaagc agagataaga tacaatcaag aaggtaagta tcattcagct
    12121 atattgtcgg aagcaatgat aacttatgaa ataaatgtat caaaggatac ttttatcaaa
    12181 ggaaatgaaa gttggcaaaa accatttgga attaagcctg acaataacta ttctcaaatg
    12241 gtaaaaacta tagcaaatag tattgtacat aaagacaata aagaaacatt tttaaataca
    12301 tttttatgtg aaaacttatt ggatgcatat aaaaataatg tgactgaaat aaaattagaa
    12361 tatcgaagaa tgaatcaaga aaataaaatg atttgggtca tttgtacaat gcacttaata
    12421 aaagattcta ttacgaacga tataaaagca cttgcttatg ttaaagatat tgacaagcaa
    12481 aaaaatgaag aaattagatt aaaattaaaa gctgaaagag atactcttac aggattatat
    12541 aataaaggta ctacagaaaa attgattaat gatttcttga actctgagga agcaagctta
    12601 ggaatgcatg catttttaat tgttgatata gataatttta aatctgtgaa tgataattta
    12661 ggacatgtat ttggagataa agtattattt gaagtttcta aaaacctaaa acctatattt
    12721 agaaaagatg atatagtagg tagaattggt ggagatgaat ttatagtatt cttaaaaaat
    12781 attcagtctt ttgagaatat caaaaagaaa gcagaaaaaa tatgcgatat atttagaaat
    12841 tcttatacag aaaataaaaa gacatataaa atatctggaa cagttggaat ttcatttgta
    12901 ccagaacatg gaactgtatt tgaagaactt tataaaaaag cagacatagc actttattat
    12961 gcaaagagca aaggaaaaga taagtatgca ctttataatg attgtatcta ccaaaatgaa
    13021 cttgaaaata atataagtga taataatata aagttagcag ataaatgtga gaaatccaaa
    13081 ccagtactta aagaaattct tgattctatt gataattata tctatatagt gaatccaaat
    13141 acttatgaac ttctttttgt caataataag gtgtctcgtt tggatttaga gataaaatta
    13201 ggagaaacct gttataaatc actattaaaa tctgatagac catgtaataa ttgccctctt
    13261 aacggattag aagaaaataa gcattcaaaa ttcaaaatag agacaaatac atttggtaaa
    13321 aatatcagta tagcaagttg gattaattgc atagatggag aatacaactg tcttatagag
    13381 tgtatagatt cttctttata caaaaataaa taaaaaagga ctatgaagat atgttaaata
    13441 gtataacttt gatacttggt ataatattta caatttacta tttttatctc aaaatagttt
    13501 ttggaggaat ttcatttagt gagattttct tagttgtagg aattgtacta attatctatc
    13561 aaatatttaa gaaaaaaatt aaagaaaaga aggtttttta tagggtgtta aaaataataa
    13621 tcagcatttt tttaatagta tttgtagtta ctgagagtct aattattttt tatcccaaaa
    13681 atagtttaga atcaaaaagt gattatctct taattttagg agcttctgta aaaaagacta
    13741 caccaagtac aaccctgaag ggtaggttag acactgcatt gaaataccta aaaattaatg
    13801 ataattgtta tgtggtagta tctggtggta aaggaagtgg agaaaaaata actgaggcaa
    13861 aagctatgaa agattatctt ataaaaaatg gtatagataa aaataggata atagaagagg
    13921 ataaatccac gaatacttat gagaatttta aatattcaaa attgaagata gaagaacata
    13981 gtcaaagaaa actaagcgat ttaaaagtaa aaatagtaac aacagatttt catgttctca
    14041 gaagtaaaat attagcatat agaaatggat ataaaaatac gtctttttat gctagtaaat
    14101 caaaactttc atttgtacca acttactata caagagaatt ttttgcatta tggaaaacaa
    14161 tcatttttga tagataataa ataaaaagac tagatataaa ctcatatcta gtcttttcta
    14221 ttcccttaat tctaatccat tttccaactt tacttgttgt agaaatttca atattgggat
    14281 ttacaagtaa ttgcttataa gaagttttat atttttcgat tccaaaatat aattttcctt
    14341 cataatccat tataaatcca aatgg
//
LOCUS       DAEPKC010000103        14103 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.103, whole genome shotgun sequence.
ACCESSION   DAEPKC010000103 DAEPKC010000000
VERSION     DAEPKC010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14103)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14103)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14103
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.103"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(802..1512)
                     /locus_tag="KR294_003093"
     CDS             complement(802..1512)
                     /locus_tag="KR294_003093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0241152.1"
                     /translation="MTSICICDDEKQQRNMLNKIITREMDLWGYPYQIKEYSNGESLV
                     YNLEHENYYIDIIFLDIELGKSNGVDIAKTIRKHSKDTIIIFVTGFSDYVFHGYDVGA
                     LNYILKPYKTEKICKVLKEALKKLEQWKENFITVQIGTNLCKINTKDILYFKSELRKL
                     TVVTFDKTLEYYGKLNDMETVLPSNFIRTHQRYIVNLNHVDSITQTYAKVQNEKIPIS
                     RKKYQEVVGKFTRYMLEP"
     gene            complement(1896..4007)
                     /locus_tag="KR294_003094"
     CDS             complement(1896..4007)
                     /locus_tag="KR294_003094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0241153.1"
                     /translation="MTINKLYSKLRAYNWKNYTTLFFCIILSVVLVTSYALIYFSPTI
                     QNILPTGGDSRKQATMIFSVAILGCAVFTTYASSLFLKFKSKEIGIFMALGTDKKKLK
                     KLLFSEILLISIVCCFLGLILSIPVSFGIWKIFQLVIIDTREMTYHFGTQGFIYGFIF
                     SVFVTLCIFILSVKFINRTNIIDILNDQRISEPIQDVKDWYGILGIIFIILGIFLGYL
                     VPSLTINKLNYKLPSIWSFTYLLSLIGIYMIMTYIVVHAKRGKHPEKYYKNIISTSMM
                     RFMGRQTVKNMCVISFLIAGALFAVFYVPNMVTGIYDTLKNNPIDYTFTYNQRDKQVS
                     KKDIEQLADKHNIKIQNYMEIPSIELIVDGVESIYHKDGTIEKVYMKKSSYDMFFNSK
                     DFSKLIGKPITIKNGEYLAVVNKGNENQDYKYTKFISSPVTEKEIPFRYAGKIIFNGS
                     FFQNRSMNAYVLNDEDYKSFTKDLSIKNYNNSILFNVDKDTYAFANDLKKEIIKRTSK
                     EMGMFSGYDEYVKKRYESTGRKYFMDEEYPSGEGHLKLDPNNNQLYLNWKYYPNFKIL
                     QSQDMIKNMAVFLMLFIYVAIICFTAVGIIAYTRGVTIAINHKQVFMDLNRLGANNDY
                     IKFCIRNQLKKVFSYPLIAGSFLIYLFNFMIMLNNDGRIVNSEVNALLINLGFIGICG
                     VYMYLIYLLTYKKFKKIIGIL"
     gene            complement(3997..4749)
                     /locus_tag="KR294_003095"
     CDS             complement(3997..4749)
                     /locus_tag="KR294_003095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0241154.1"
                     /translation="MLKVNQLCKSYKTGSKTYPVLKNISFEINKGEFVAIMGSSGSGK
                     TTLLNCISCFIPIDNGEIILGNNNIRNLKEKELSEVRNQQLGFVFQDFMLFDGLSVFE
                     NICVPQIIKGSQVLQMENRAINLCELFGIEHIRKKYPAEISGGEKQRTAVARALMNNP
                     DLILADEPTGNLDSKSCRTVIESFLKAKQELDATILMVTHDSFAASFCDRVIVLKDGI
                     IYKEVVKSNSRHKFLDELLEVLKEMGGAQDDN"
     gene            complement(6015..6191)
                     /locus_tag="KR294_003096"
     CDS             complement(6015..6191)
                     /locus_tag="KR294_003096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241155.1"
                     /translation="MFFTFIGVISAILLLCTIICGLWIKLNNRNNDSNSHFTFSILSI
                     AFSLLIVVAFLVRN"
     gene            complement(6295..6903)
                     /locus_tag="KR294_003097"
     CDS             complement(6295..6903)
                     /locus_tag="KR294_003097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH0241156.1"
                     /translation="MGKLLRGKIMKADSTKEQLINATIQLLSSHRDVSSITAREIVAK
                     ANVNLAMINYYFKSKEELINISIKKFLKRHMDEYKATHDTKNLAPKQQLREILIAFFD
                     FIGEHSQFIKISVPYILIQEEIVYPFEILPLIKAHYENQNNKKTEAEYRTIAYQITSF
                     IQLLFLRSNAFFKYSGIDILNIEQRNGLIDFQLDLLLVDITK"
     gene            complement(7002..7826)
                     /locus_tag="KR294_003098"
     CDS             complement(7002..7826)
                     /locus_tag="KR294_003098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH0241157.1"
                     /translation="MFKIGEVSKLTQISIRMLRYYDELGILKPAEIDKYTGHRLYSVE
                     QISILQRIVLLRDSKFSVAEIANIVHNWNDEFVIKELNRKKNEIQKEINQEQQRINKI
                     DKFIEAINCDKDEIHYNVVFKKIPSYKIISLREIIPDYQSEGILWEKLSKFIKEEHIE
                     VSRQSNNNIAFYHDEEVKDNGVDIEVGMVVKKIGKNKSGFIYRETEEIDMMACTMVYG
                     PYENIAGAYESFCYWLDKNSDYQISGINRQIGHKGEHNEINPENYLTEIQIPLIKV"
     gene            complement(8004..8897)
                     /locus_tag="KR294_003099"
     CDS             complement(8004..8897)
                     /locus_tag="KR294_003099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBH0241158.1"
                     /translation="MQLYNTPFNTNKHLIYFFTFTLVLNWIFSLTPALLGITNTILGE
                     IIFYLAYTSPAIVGLFFISTIYPQSAKQDFIYRYLSFKEIRIKWILLTILFFALTFIT
                     SLIIGNYFNVKTSDIDWIHIAVFRPSKIAYMLLASFILSILSQEAGWRGYAIDKLLVR
                     FGFIGSSIILGLVCGIWYLGSYFTPNQIPYNLAQYSLFDAFLFIPNIVLLNFIINFVY
                     INTSRSILSAGLVHMMYYFFNIQLLLHYPIKLCVIAQYVQIIFGLIFLVYMISSNKFK
                     QKVNSEIEQIKSDDFEFELDW"
     gene            complement(9154..9591)
                     /locus_tag="KR294_003100"
     CDS             complement(9154..9591)
                     /locus_tag="KR294_003100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family transcriptional regulator
                     DNA-binding domain-containing protein"
                     /protein_id="HBH0241159.1"
                     /translation="MKIHVEQGINCDDIEITIKCSALDNNIEKIISLLSTPLLDIKGK
                     KSGEIYKLNVCDILYFETVGNKTFAYYEDDVFEIDLKIYKLSKLLANTSFSRISKSMI
                     LNMDYIKSIKVISHNRMQATLKNNEKVIINRRYIKNIKEKLNI"
     gene            complement(9848..9997)
                     /locus_tag="KR294_003101"
     CDS             complement(9848..9997)
                     /locus_tag="KR294_003101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvrJ family protein"
                     /protein_id="HBH0241160.1"
                     /translation="MDDSLQLLITNVGFPIALSMYLLVRIEGKLNTLSNSIDTLSKNI
                     LIFKK"
     gene            complement(10010..10240)
                     /locus_tag="KR294_003102"
     CDS             complement(10010..10240)
                     /locus_tag="KR294_003102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2922 domain-containing protein"
                     /protein_id="HBH0241161.1"
                     /translation="MEIKKKLVMSFKNVKDKQVSFSIENPKDDLTEENIKSVMDLIVS
                     KNIFSVGGFDLASVVEAKVVETNTTPYDLVIE"
     gene            complement(11058..11279)
                     /locus_tag="KR294_003103"
     CDS             complement(11058..11279)
                     /locus_tag="KR294_003103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1659 domain-containing protein"
                     /protein_id="HBH0241162.1"
                     /translation="MEVVSTKNLSSIKLKLDAGFDDKGKAVVKSKSFANVKAEALNED
                     VYAVAEAIASLQENPIVDILKLDSTSLSK"
     gene            11859..12116
                     /locus_tag="KR294_003104"
     CDS             11859..12116
                     /locus_tag="KR294_003104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBH0241163.1"
                     /translation="MKIKVEDIPVQFHAMVEIIGIDKFIEVAKLYGGTNTYIPTYKGL
                     FRYARNRDIVKQFNGVNHNELAIRYNMCVSNIKRILNENNV"
     gene            12585..13823
                     /locus_tag="KR294_003105"
     CDS             12585..13823
                     /locus_tag="KR294_003105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conserved phage C-terminal domain-containing
                     protein"
                     /protein_id="HBH0241164.1"
                     /translation="MNKGFYKLNSVVLNFDIKNDVNKIRFNHYIMRKENIQRLQGTLP
                     NGQFYMTVRRAATDLQLSISTISRLVKEFLDLGIIRLVSKGVKGNRSVYSYVSIEFNG
                     SLFDDSKYMELDCVCNDEFIDNSGIEFDCDSKDNSFNGDINVETVHCINEYLSDDDVE
                     HNYNNFHNKDTIKDKAISNISTIKKYIDESFDKNKSENSNLQQESINFNFNDTCNEID
                     KRTNNSIENNQNKRPMRLSDISLLSDKGMTNKKNYFNHNHGIQKGTKSVTKKKESLNK
                     FNKKNIQQSIINMLNKKSGKNFKIDSPISIKLINERLKEGYVLEDFYKVIEVKVAKWK
                     NTIMEMYIRPETLFSYKFESYVNENISMKSQSNVHPCKEGNSNDSSNYIHSDYTTYDG
                     SVRERKKYENVRYWNPICEI"
BASE COUNT         5284 a         1671 c         1852 g         5296 t
ORIGIN      
        1 cttttgagtg tataagttcc tcatatatag ggttgtttat aaaaagaaaa ttaagcccaa
       61 ttataatagg ataaaatatc atgacaactg atattatagg aattaatttg cttttgctac
      121 atattataag tagtataaaa tatccgaata gtgtaaacaa aatatttacg gggtcggaaa
      181 gccatattat catttgacta ataatagagt agcccaaaat caatatgatt ttgaaaatcc
      241 aatgattcct aaagtctata aaataggaag tcaacgtata aagaaaaaag gctatgaaaa
      301 tattgattaa tattagaata aaatttatgc ttgtagagat taaagaataa gtgcccattt
      361 aatatacctt tctattaatt aagattctgg aaactaagtt ttaaaaaatt aaatcttaaa
      421 aattaaaatt ctggaaatta aatttcaaag aattgatttt gaaaaataaa attctagaga
      481 ttgaacttca aaaaattgag ttttaaaaga ttgaaatttt aaaaattaag tttcaaaaaa
      541 ttaaatttga aaaaaaactc taaaaactaa gcttcaaaaa attaaatttt gaaagattga
      601 aattctagaa actaagcttt aaaaaattaa gtttgaaaaa acaaaactct aaaaactaag
      661 cttcaaaaaa ttaaattttg aaagattgaa attctagaaa ttaatcttca aaaaattaaa
      721 tttgaaaaaa caaaactcta aaaactaagc tttaaaaagt taagtttcaa aaataaaatt
      781 ctagagattg aacttcaaaa attaaggttc taacatatac cttgtaaatt ttcctacaac
      841 ctcttgatat tttttacggc ttataggaat tttttcattc tgaactttgg cataagtttg
      901 agttatacta tctacatggt ttagattgac aatatacctt tgatgcgtac gtataaaatt
      961 agagggaaga acagtttcca tatcatttaa ttttccgtag tattctaatg ttttatcaaa
     1021 ggtaactaca gttaattttc ttagctcact tttaaagtag aggatatctt ttgtattaat
     1081 tttacaaaga ttagttccaa tctgaactgt aataaagttt tctttccatt gttctaattt
     1141 ttttagtgct tcttttaata ctttacatat tttttcagtt ttataaggtt ttaagatgta
     1201 gttcaaagct cctacatcat atccatgaaa tacatagtca gaaaaacctg tgacaaagat
     1261 gattatagta tcctttgaat gttttcgtat agtttttgct atgtcaacgc cattactttt
     1321 tccaagttca atatctaaaa aaataatatc tatgtaataa ttttcgtgtt ctagattgta
     1381 tactagactt tctccatttg aatattcttt tatttggtag gggtagcccc acaaatccat
     1441 ttctcttgta atgattttat tcagcatgtt tctttgttgt ttttcatcat cacaaataca
     1501 aatcgaagtc aattttttat ctcctttcaa attttatatt tatatagtta agtatataat
     1561 atattttgct acctagatat ataaaatgaa ataacaatta tatccagata gcaaaataaa
     1621 attttttata ttagtatact tacacttaaa actattctat taaacttatt ctgaagtgct
     1681 aatgattttc ttattaaaaa atctaacaat ctttcttatt ataaaataca aatgctttta
     1741 ttattataaa aagtaatgat tttattactt taaaaatcta ataacctttc ttattataaa
     1801 acaccaatga ttttattact ttaaaaatct aataaccttt tttattataa aacaccaatg
     1861 attttattac tttaaaaatc taataacctt ttttattata aaataccaat aatttttttg
     1921 aatttcttat aagttaatag atatataagg tacatataaa ccccacaaat ccctataaaa
     1981 cctaagttta tcaaaagagc attgacctca ctattgacga ttctaccatc attatttaac
     2041 ataatcataa aattaaacag ataaattaaa aaacttcctg caataagagg gtatgaaaat
     2101 actttcttta attgatttct aatacagaac tttatataat cattgtttgc tcctaatcga
     2161 tttaaatcca taaagacctg cttgtgattt atagctatag taacacccct tgtatatgca
     2221 atgattccta ctgctgtaaa acatatgatt gccacatata tgaataacat taagaagact
     2281 gccatgtttt ttatcatatc ttggctttgt aaaattttaa agttaggata gtatttccaa
     2341 ttaagataca actgattgtt gtttgggtct agttttaaat gaccttcacc acttggatat
     2401 tcttcatcca taaaatattt tcttccagtt gattcataac gtttttttac gtattcatca
     2461 taaccactga acatgcccat ttccttagat gttcttttta taatttcttt ctttaagtca
     2521 ttggcaaaag cataggtatc tttatctaca ttaaatagta tagaattatt gtaatttttt
     2581 atggataaat ctttagtaaa tgatttataa tcctcatcat taaggacata ggcgttcata
     2641 cttctatttt gaaaaaaaga accattaaat attatttttc cagcatatct aaaggggatt
     2701 tctttttctg tgactgggct tgatataaat ttggtatatt tataatcttg attttcattt
     2761 cctttattta caacagcaag atattcacca ttttttatag ttattggttt gccaattagc
     2821 ttggaaaaat ctttagaatt aaagaacata tcataggagc tttttttcat atataccttt
     2881 tcgatagttc catctttatg atatattgat tctacaccat caacaattaa ttctatagaa
     2941 ggaatttcca tatagttttg aatttttata ttgtgtttat ctgctaattg ttcaatatct
     3001 ttttttgata cctgtttatc tctttgattg taggtaaaag tataatctat agggttattt
     3061 ttaagagtat catagatacc tgtaaccata ttaggaacat agaatacagc aaataatgct
     3121 cctgcaatca aaaatgaaat aacacacatg ttttttactg tttgtcttcc cataaatctc
     3181 atcatgctag ttgatatgat gtttttatag tatttctctg gatgttttcc tcttttagca
     3241 tgtacaacta tgtatgtcat aatcatatat attccaataa gagagagtag ataagtaaag
     3301 ctccatatag atggtagttt ataatttaat ttgtttatag ttagtgaagg tacgagatat
     3361 cctagaaaaa taccgagtat aataaaaatt atacctaata taccatacca gtcctttaca
     3421 tcctgtattg gttcagatat tctctggtca tttaatatat caattatatt tgtacgatta
     3481 ataaatttta cagaaagtat aaatatgcat aatgtcacaa atacactaaa tataaatcca
     3541 tatatgaatc cttgagttcc aaaatgatat gtcatttctc tggtatcaat aatcactaat
     3601 tgaaatattt tccatatacc aaaagataca ggaatactta atataagacc taaaaaacag
     3661 catactattg aaattaacaa tatctctgaa aatagaagtt tttttaattt cttcttatct
     3721 gttcctagag ccatgaaaat accaatttcc ttgcttttaa attttaaaaa gagggaagaa
     3781 gcgtatgtag taaagacagc gcatcctaat atagcaactg agaatatcat tgtagcctgt
     3841 tttctgctat ctccaccagt tggaagtatg ttttgtattg ttgggctaaa ataaattaga
     3901 gcatatgaag ttactaatac cacagaaagt attatacaaa agaataaagt tgtatagttc
     3961 ttccaattat aggctcgaag tttactgtat aatttattaa ttgtcatctt gagcgcctcc
     4021 catttctttt aaaacttcta gtaattcatc taggaattta tgtcttgaat ttgattttac
     4081 aacttcttta taaattattc catctttaag cacaataact cggtcacaga agcttgctgc
     4141 aaagctatcg tgtgtaacca tgagtatagt agcatctaat tcttgctttg cttttaaaaa
     4201 tgattcaatg actgtacgac aagacttact atcaaggtta ccagttggtt catctgctaa
     4261 tattaaatct gggttgttca tgagtgctct tgctactgct gtacgctgtt tttctccacc
     4321 agatatttcg gcagggtatt tttttctgat atgttcaata ccaaatagct cacatagatt
     4381 aattgcacgg ttttccattt gtaagacttg actacctttg ataatttgtg gaacacatat
     4441 attttcaaag acactaagac catcaaatag catgaagtct tggaatacaa atcctagttg
     4501 ttgatttcta acttctgaaa gttccttttc ttttaaattt cttatattat tatttccaag
     4561 aattatttcc ccattatcaa ttgggataaa acatgaaata caatttaaaa gagtagtttt
     4621 tccacttcct gatgaaccca tgattgcgac aaattctcct ttgttgattt caaaagaaat
     4681 attttttaat acaggatatg ttttactgcc tgttttatat gatttacata attggtttac
     4741 tttaagcata tatatcatcc tcactttcat ttatcttgta agtcaatgat agcatttgaa
     4801 aggggaggag ggatatgagc tatattgtaa tagttggatg tttttttgta atgtttgaaa
     4861 atatattgtt tggatagtgt gagaggttat tattatagtt aaattgatta tattattgga
     4921 ggatttagag ggttattttt aggtattaat tgttgtgcta aagtaatatg atgtggaaca
     4981 ttgaaggtgt agttagaaaa gaagtatata gtaaaagtaa aaaggttata gaataacgaa
     5041 tgttgtattg aaaaaaatga tgtaaataat gtatagtagg gttaaaaaga aaaaaagaat
     5101 tatagagcag taagattatt taatagaatg tattgtaaat aatttgaaag gatttagggg
     5161 ctattaacac aatgtaattg agaaaatata ttggagtttt ggaaataaat aggttgttag
     5221 aaacaattga aatgtataat aaaaaggtta aaaagtatta ttagtatagg tatgatagat
     5281 aattttagaa agtggaagta ttttagacta tgctgaaaag tgattgatat gattttgaga
     5341 tattaaaata ttactatatt atagtaaaga agttaaaata ataaaatgtt gtaataataa
     5401 aggtttgtag tataataaag aactgtaata aataagactt tgcaatgtaa tagaaatgct
     5461 gtaataataa aagtctgtag tataataaag aactgtaata aataagactt tgcaatgtaa
     5521 tagaaatgct gtaataataa aggtctgtag tatagcaaag aactgtaata aataagagat
     5581 tgtaataata aaagtctgta gtgtaataaa gaactgtaat aaataagact ttacaatgta
     5641 atagaaatgc tgtaataata aaggtctgta gtataataaa gaactgtaat aaataagact
     5701 ttacaatata atagaaatgt tgcaataaca aaacaccata ataaataaga gtttgcaata
     5761 taatagaaac actgcaataa ataagagatt tcaatataat aaaagtctgt aatataacaa
     5821 aatcctataa taaataagat tttacaatat aataaaaatc ctataataaa taggactctg
     5881 taatataata aaatgctgta acaacaaaac actataataa ataagaccct gtaatataat
     5941 aaaaatacta taatatagta aaaatcatgc aataataaaa atctataata ataaacctca
     6001 gcataacaaa gacattaatt tcttactaaa aaggccacca caattaacag tgaaaaagca
     6061 attgaaagta ttgaaaaagt aaaatgagaa ttagagtcat tattacgatt attaagtttt
     6121 atccataaac cacatataat tgtacacaac aataaaattg ctgatattac tcctataaat
     6181 gtaaaaaaca ttaaaattcc tcccccttat ttaatgcaag tatttttagt caatgagaat
     6241 attttcaaac gttaccataa aataaaaaaa tgtacataaa aaattaatat agtattattt
     6301 tgtaatatct accaataata aatctaattg aaaatctatt aaaccatttc tctgttcaat
     6361 attaagaata tcaataccac tatacttgaa aaaagcatta gaacgaagaa aaagcaactg
     6421 aataaatgaa gttatttgat acgcaatagt tctgtattca gcttcagttt ttttgttatt
     6481 ctgattttca tagtgagcct taattaaagg tagtatctca aatggataaa caatttcttc
     6541 ctgtatcaat atatagggta cagaaatctt tataaattga ctatgttcac ctataaaatc
     6601 aaaaaatgca attagtattt cccttaattg ctgtttaggt gctaaatttt tagtatcatg
     6661 tgtagcctta tattcatcca tatgacgctt taaaaatttt ttaatagaaa tattaattaa
     6721 ctcctcttta gatttaaaat aataattaat catagctaaa ttgacatttg ctttagctac
     6781 aatttctcta gccgtaatgc ttgaaacatc tctatgtgaa gatagtaact ggattgtggc
     6841 attaattaat tgttcctttg ttgaatctgc tttcataatt tttcccctta aaagtttccc
     6901 cataaaaaaa ttaaacatgt ttaacacacg tttagatact atcatgaaaa ttttgggatg
     6961 tcaatgggtg attagtactt aagtatttaa gtactaatct attagacttt tataaggggg
     7021 atttgaattt ctgtaagata attttcagga tttatttcat tatgttcacc tttatgtccg
     7081 atttgtctat ttatacctga tatttgataa tcactatttt tatctaacca ataacagaac
     7141 gattcatatg caccagctat attttcatat ggaccataaa ccatagtaca tgccatcata
     7201 tcaatttctt ctgtctcacg atatataaat ccagatttgt tctttccaat cttctttaca
     7261 accattccaa cttcaatatc tacaccatta tctttgactt cttcatcatg gtaaaaagct
     7321 atgttattgt tggattgacg tgatacttct atatgttctt ctttgataaa tttagatagc
     7381 ttttcccaga gtataccttc agattggtag tctggaatta tctctctaag tgatatgatt
     7441 ttataacttg gaatcttttt aaagacaaca ttgtaatgaa tttcatcttt atcacagttt
     7501 atagcttcta taaatttatc aattttattt attctttgtt gttcctgatt tatttccttt
     7561 tgtatttcat tcttttttct attcaattct ttaattacaa attcatcatt ccaattatgt
     7621 acgatatttg ctatttctgc aacgctaaat tttgaatctc tcaataatac aattctttgt
     7681 agtattgaaa tctgttcaac tgagtataat ctatgacctg tatatttgtc tatttctgca
     7741 ggttttaaaa taccaagttc atcataataa cgcaacatac gaatagaaat ttgtgttagt
     7801 tttgaaacct ctcctatttt aaacatgaaa atatgacctc cttttcactt ataatcagta
     7861 tatattttgt ttttatatac ttcaagcgtt tgtggaaata caattatttt ccagatgttg
     7921 caataaatta tagagagtaa attatattta agtagtaatc gtatcaaatc atagattatc
     7981 ttaatttata attcatatta aaattaccag tctaactcaa attcaaaatc atccgacttt
     8041 atctgttcaa tttcagaatt taccttctgt ttaaatttat tagaagaaat catatataca
     8101 agaaatatta aaccaaatat tatttgtaca tattgagcta ttacacataa tttaataggg
     8161 tagtgtagaa gtaattgaat gttgaaaaaa tagtacatca tatgaactaa cccagctgat
     8221 aaaatgcttc tacttgtatt gatatataca aaattaatta taaagtttaa aagtacaatg
     8281 tttggtataa ataaaaaagc atcaaatagg gagtattgtg ccaaattata tggtatttga
     8341 ttaggtgtaa aatacgaccc tagataccag attccacaaa caagccctaa aataattgaa
     8401 gagcctataa atccaaatct aactaataat ttgtcaatgg catatcctct ccatccagct
     8461 tcttgactaa gtatactcaa tataaaactt gctaatagca tataagctat tttagaaggt
     8521 ctaaacactg ctatgtgtat ccaatctata tcagaagttt ttacattaaa gtaatttccg
     8581 attattaacg aagtaataaa agttaaagca aaaaataata ttgttaatag tatccatttt
     8641 attctaattt ctttaaagct taggtatcta taaataaaat cttgttttgc actttgtgga
     8701 tagattgtag aaataaaaaa tagacctaca atagctggtg atgtatatgc aagataaaaa
     8761 atgatttctc caagtattgt atttgtaatt ccgagcaacg caggtgtaag actgaatatc
     8821 cagttcaata ctagcgtaaa tgtaaagaaa tagattaagt gtttgtttgt attaaagggg
     8881 gtgttatata gttgcatttt ttcactatcc ttccgtttta taatgaagtt ttaattttta
     8941 ttaattgttt atttattttt atatgtatta agttatcgct tgatgttagt tattgcctat
     9001 aataatatcc tattttttat attttgatta attattttta cactaaatat aattaattag
     9061 tatttaatat tgaatatatt atattattat taattattaa ataggtcaat aaatttgcaa
     9121 ttagtgatat taataaatta ctttagattt ttattaaatg tttagctttt ctttaatatt
     9181 ttttatataa cgacgattta taataacttt ttcgttgttt tttaaagtag cttgcatgcg
     9241 attatgtgat attactttta tactttttat gtagtccata tttaaaatca tggatttaga
     9301 tattcgtgag aaggatgtat tagctaataa ttttgataat ttatatattt ttaaatcaat
     9361 ttcaaataca tcatcttcat aataagcaaa tgttttattt ccaactgtct caaagtataa
     9421 aatatcacag acattgagtt tataaatctc tcctgatttt ttacctttta tatcaagtaa
     9481 cggtgtactc aataatgaaa ttattttttc aatgttatta tctagagcag aacattttat
     9541 ggttatttca atatcatcac aattaatacc ttgttcgaca tgtattttca ttaatcatca
     9601 cctcatttta ttactgtcat tagaatagca ttatatctta ttgagtccaa ctagatgcgt
     9661 tctaaatttc aaattaagca tagtgaaatt caaaaataaa acagtgaaat tcaaatttga
     9721 ggtggtaaaa ttcaaaaaaa tactatggat atttggataa attatccaaa tatcctagta
     9781 tttcacatag aatatgtcta attattttac aaatagacct attttatgac ttacatatat
     9841 tgtcaaatta cttcttaaat atcaaaatat ttttggataa tgtatcaata ctgtttgata
     9901 aagtatttaa tttaccctca attctaacca ataagtacat ggatagagct ataggaaaac
     9961 caacattggt tattaacagt tgtaaactat catccataaa attagccccc tattctataa
    10021 ctaagtcata aggagtggta tttgtttcca caaccttggc ttcaacaaca gaagctaggt
    10081 caaatcctcc aaccgaaaaa atatttttag atactatcaa atccatgaca gattttatat
    10141 tttcttcagt taaatcatcc tttggatttt ctatagaaaa agaaacttgt ttatccttta
    10201 catttttaaa gctcatgact aattttttct taatttccat ataattacct ccgatataat
    10261 aatttatatt ttaattgttt gcttgttaat attggtattt taattgtcaa tattaatgtt
    10321 ttgcttgtta gtattaatat ttcaattgtc aatattaatg ttttgcttgt tagtattaat
    10381 atttcaattg tcaatattag tgtcttgctt gttagtatta atatttcaat tgtcaatatt
    10441 aatgttttgc ttgttagtat cagtgtttca attgtcaata ttagtgtttt gcttgttagt
    10501 attaatattt caattgtcaa tattagtgtc ttgcttgtta gtattagtat ttcaattgtc
    10561 aatattagtg ttttgcttgt tagtattagt atttcaattg tcaatattag tgttttgctt
    10621 gttagtatta gtatttcaat tgtcaatatt aatgttttgc ttgttagtat tagtatttca
    10681 attgtcaata ttagtgtttt gcttgttagt attaatattt caattgtcaa tattagtgtt
    10741 ttgcttgtta gtatcagtgt ttcaattgtc aatattagta ttttaattgt tgactctagt
    10801 tattgctgat atagaaaata tttaatttat ttcaattaat tagattaaag tagggtagca
    10861 tctaaaatag ctaacatgtt taagttgaaa tacgtttaat atattaattt ttcaaagcat
    10921 taatatatta aagttataat caaaattgaa gttataatct gccaaatcta tagcgtatta
    10981 agtgcgttat ataacttaat cttttatata aagagttaat ttttttaatt tgtaaagcag
    11041 agtacgttta aaaggtacta tttagataat gatgtactat ctaattttaa aatatctaca
    11101 atagggttct cttgaagact tgctattgct tctgcaacag cataaacatc ttcatttaat
    11161 gcctctgctt ttacatttgc aaatgattta cttttaacaa ctgccttacc cttatcatca
    11221 aaaccagcat ccaattttag ttttatacta gataaatttt ttgttgaaac aacttccata
    11281 aaattacctc ctaaaaattt aatttcaaag atttgtcgac tttctttgtt agctataata
    11341 ctatcatcta agataatatc ggagttaaac agtaatttct aaagattttt tgtgtaaatt
    11401 tttataggaa aaattttact tttttgctga tgaaaaagtt tacaagttat ttgtgaagat
    11461 atgttcttag tgttttgaaa tagtatttgt atatattcat gcttagttga gatagttttg
    11521 tatggatttt catatgtgta gagttaaatg ttaggtacta aagtttatgt taaattaaat
    11581 gttaaagctt atgttaaaaa ttttattaaa tttaatctgt aaataaaaaa gttaaaagtc
    11641 caatattaac attttacttt taaaccatta aaatctttat taaagctaac aaagttataa
    11701 gttatgagaa attttattaa agttaataca aaaattaatt ttaaagctaa gaaatttttt
    11761 attagattca ataaaactaa taaatatagt ttagtcaata atgtattaaa taaaaacttt
    11821 gttaagtcta taaaaatatc ttaaaggagg tgtaacttat gaagataaaa gtggaggata
    11881 taccagttca atttcatgca atggtagaaa taattggaat tgataagttt atagaggttg
    11941 ccaagttgta tggaggaaca aatacttata tacctacgta taaggggctt tttagatatg
    12001 ctagaaatag ggatatagta aaacaattta atggagtcaa ccacaatgaa ttggctatta
    12061 gatataatat gtgtgtaagc aatattaagc gaatactcaa tgaaaataat gtttaaatat
    12121 aataaaataa tgtttaaaca taatgaaaat agccttgtta aacgtaagag taaagacaaa
    12181 gaagatgttt tataaagttt ttttagacaa attaactaaa tttactactt attaatttaa
    12241 atacattgta tattctataa aaaaatttgt taaatactgg agatatattg agaatacaaa
    12301 gaaaatggtc gaaaatattt gttggctaaa aaatagataa aatgatacaa ttgcttgtat
    12361 aaaggggaaa aataaataaa taaactatat aaataaagaa atagcaatta atatgacata
    12421 atatatttat aaaattaaga atataaatag atattttaag gtattagttg ttaaattagg
    12481 aaatattaaa aaaaatatat atttatattt aaactatttt gttatttata taaaaatact
    12541 tatctagtta ctagcaatta ttagtagaaa tgggggaaat agagatgaat aagggatttt
    12601 acaaattaaa ttcagtggta ttgaactttg atattaagaa tgatgttaac aagataagat
    12661 ttaatcatta tataatgaga aaagaaaaca tacaaagact tcaaggaact ctgccaaacg
    12721 gacaatttta tatgacagtg agaagagctg ctacagattt acaactttct atttctacta
    12781 taagtaggct tgtaaaagag tttttggatt tagggataat aagattagtg tctaagggtg
    12841 taaaaggtaa tcgttctgta tatagttacg taagtataga gtttaatgga agtttatttg
    12901 atgatagcaa atatatggaa cttgactgtg tatgtaatga tgaatttatt gataatagtg
    12961 gcatagagtt tgattgtgat agcaaagata attcttttaa tggagatata aatgtagaaa
    13021 ctgtgcattg cattaatgag tatttgtctg atgatgatgt agagcataat tataacaatt
    13081 tccataataa agatactata aaggataaag ccatttctaa tattagcact atcaaaaaat
    13141 atattgatga atcttttgat aaaaataaat cagaaaattc taacttacaa caggagtcaa
    13201 taaatttcaa ctttaatgat acatgcaatg aaatagataa aagaacgaat aatagtatag
    13261 aaaataatca aaataaaagg cctatgagat tgagtgacat cagtctttta agtgataaag
    13321 gtatgacaaa taaaaagaat tactttaatc ataatcatgg tatacaaaaa gggactaaat
    13381 ctgtaacaaa gaaaaaagaa tccttaaata aatttaataa aaaaaatata cagcaaagca
    13441 ttataaatat gctaaataaa aaatcaggta agaattttaa aatcgattct ccaataagca
    13501 taaaacttat caatgaaagg ctaaaggaag gctatgtctt agaagatttc tacaaagtta
    13561 ttgaggtaaa agtggctaag tggaaaaata ccataatgga aatgtatata agaccagaaa
    13621 ctttgtttag ctataagttt gaatcctatg taaatgaaaa catatctatg aaaagtcaaa
    13681 gtaatgttca cccatgtaaa gaaggcaata gtaatgatag cagtaattat atacattctg
    13741 attatacaac atatgatggc agtgtgcgtg agagaaaaaa atatgagaat gtaagatact
    13801 ggaatcctat atgtgaaatt taattagttt aagaatgtat ttatgataaa taagatatta
    13861 atagagaata gtgagctata gcaaatgata tatcaatagt tggtagtaag ttatattaag
    13921 caagatatta ctatcaggta gtgaattata ttgaacgata tatcaataat tggtagtaaa
    13981 ttatattaag taagatatta ctatcaggta gtgaattata ttgaacgata tattaataat
    14041 tggcagtaaa ttatattaaa taagatatta atatcgagta atgaattata ttgaacgata
    14101 tat
//
LOCUS       DAEPKC010000104        13983 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.104, whole genome shotgun sequence.
ACCESSION   DAEPKC010000104 DAEPKC010000000
VERSION     DAEPKC010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13983)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13983)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13983
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.104"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            455..1348
                     /locus_tag="KR294_003106"
     CDS             455..1348
                     /locus_tag="KR294_003106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfide/dihydroorotate dehydrogenase-like
                     FAD/NAD-binding protein"
                     /protein_id="HBH0241165.1"
                     /translation="MSNKIVSKRQLTDSIYLMEIEAPRVAKSSQPGQFIIIKNDEKGE
                     RIPLTIADYDREKGTVTIVFQTVGASTKKLAMFEENDFVMDFVGPLGQASEFIHEDIE
                     ELRNKKILFVAGGVGSAPVYPQVKWFKEHGLDVDVIIGARTKELIILEDDMKKVAKNV
                     YVSTDDGTYGFNGRVTDLLKDLVDNQGKKYDQAIVIGPMIMMKFMCQLTKELNIPTIV
                     SLNTIMIDGTGMCGGCRVSVGNETKFACVDGPEFDGHLVDFDQAMRRQSMYKTQEGRA
                     MLKLEEGDSHHHSNCGCGGNK"
     gene            1348..2742
                     /gene="gltA"
                     /locus_tag="KR294_003107"
     CDS             1348..2742
                     /gene="gltA"
                     /locus_tag="KR294_003107"
                     /EC_number="1.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent glutamate synthase"
                     /protein_id="HBH0241166.1"
                     /translation="MDAKKVKVPVREQEPAVRATNFDEVCLGYNKEEAMAEANRCLAC
                     KKPKCVGGCPVGIDIPGFITKIKEDDIEGAAKVIAKSSSLPAVCGRVCPQESQCEGVC
                     ILGIKSDAVSIGKLERFVADWSKENDINLSDTEPKKNQKVAVIGSGPAGLACAGDLAK
                     KGYDVTIFEAMHEPGGVLTYGIPEFRLPKQAVVQPEIDNIRKLGVKIETNVIVGKTIT
                     VDELIEDEGFEAIFIGSGAGLPMFMNIPGENANGVFSANEFLTRVNLMKAYRDDYDTP
                     ISSGKKVAVVGGGNVAMDAARTALRLGSESYIVYRRSEKELPARAEEVHHAKEEGIIF
                     NTLTNPKEILVDENGYVKGMVCIRMELGEPDDSGRRRPIEIEGSEFVLDVDTVIMSLG
                     TSPNPLISSTTKSLDINKKRCLITDENGQTSKEGVFAGGDAVTGAATVISAMGAGKTA
                     AASIDEYLKAKVNA"
     gene            3108..5327
                     /locus_tag="KR294_003108"
     CDS             3108..5327
                     /locus_tag="KR294_003108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBH0241167.1"
                     /translation="MKKREKVFDGLVFKHILILLILLVLIDLTSTIIYASNSMEITSR
                     NMIEASKRELENYLEVNISLLKALSQDDRFSNGETSLIEKGKLLSPYQKEYNLFMIGI
                     TDTKGNASSTYRENVNSIKDKPSFEKAIKTKQVVVSDIEVSNVTGDKVFIIYVPIVKN
                     NEMIGTIFASFYFQDVNNLISRSNFDDSIKFLMIDKDYTIISHPNKKYVNDKSKMLDL
                     EGNIIGTTKSEILKNINKKCQGDFLSWDNWRLYNVKYTNIKWTNWTLVSKCNIFKNFK
                     NLIVNFMIKLYFYIVIFMILWKLSNAKLIEQLKKLAYYDSLSGIKNKEKFRKDSMYIL
                     KNYYQDNFYLVQLDVNKFKYINEMFGYAEGNKILIHISQVLNNNTNKYEICARMDNDH
                     FILLIACNTEDELLNRLSKINKEICNLNTTNSSKYKIVMSSGIYKITKKDDIKKIDLL
                     IDRANIAAKSKKEKYEHSYSFFNEDTRNRLYKEKRLEDNMNKALEKGEFIVYYQPKYS
                     LDDVNEIEGAEALIRWNSPEFGFISPIDFVPLFEKNGFIVNIDMFVFEEVCKTLNKWI
                     NKGYTPVPISVNMSRVHLYRDNFIENITDLISKYNISPEFIELELTESVVFDNLNILI
                     DIMKKIKEIGFLISMDDFGSGYSSLNLLKDLSFDILKLDRGFLIETTDTKRGKIIISK
                     IVEMAKAIDIKVICEGVETYEQVEFLKEIGCDKVQGYLFAKPMVLDEFEKHLNFKFD"
     gene            5474..6220
                     /locus_tag="KR294_003109"
     CDS             5474..6220
                     /locus_tag="KR294_003109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0241168.1"
                     /translation="MNILSIRNISKTYCGNIPFKALDKVSLNIEKGEFVSVMGPSGSG
                     KSTLLNIISTVDRQSEGEVVLDGYDVSKLKGEKLAEFRRKQLGFVFQDFNLIDTLTVG
                     ENIMLPLTLEGASIKDMNIQTKSISKFLGIDKILDRKTYEISGGQAQRCAIARAIINK
                     PAILLADEPTGNLDSKSTDDVLKLFTRINKEQKVTTLMVTHEAYSASYSDRVIFIKDG
                     CIYTEIKKSESSNSFYSDILAVLSQIGGVR"
     gene            6220..8100
                     /locus_tag="KR294_003110"
     CDS             6220..8100
                     /locus_tag="KR294_003110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0241169.1"
                     /translation="MDFRKFAYNNIVRNFRAYLAYFLSSVFSIMIFFVFAVSMFHPII
                     TKSGMQSGSTAFMALMTSELIIFGFSLLFILYSLGNFLKYRLKDFGVLMIIGMSNRQL
                     KKLILIENLIIGFLAVMLGILLGLSISKLFLLYLSKLFYMNLTEFYFPVKAMLLTIVS
                     FMILFLITGPMSLKLLSKKSILELLVGTKKPKKEIKSSKLFGIIGVICLILGYAMILF
                     GNKLKINGGMYTTALLITLGIFLFFSQFTILILKYLKNKEKFYKNKVNMLLISNLIYK
                     LKDNTRLLFLITILLSATLVAFTTTSTLVSSQGEASKNNFPMVYSYFSEHNNEKEYEE
                     LQQIREAIKGYDYKELSFPVLKYNREVLLSVKNYNKLSKELGLDKISSKLEKYEGIII
                     PSSNSQEHINSLKQLKNYSIKNLNIEVKKSKNKIIFPTGLFSKVVVISDDLYNEVKGE
                     FSKINFHGFDYKNWQSSAKITENLKEKHFNLDREYNRSYFLTLPDMYLVELQQSKILQ
                     FMGVFIGVILFIAVFSFLYFRLYTDEIEDNVKYKKLSKIGLSFKNMNKIVSIEIGTLF
                     FIPYFIAIINSIISLLFLNQVLNNSFKLENLGILLLISSIYSLYFYLLKKNYTRKVWF
                     FD"
     gene            8219..9610
                     /locus_tag="KR294_003111"
     CDS             8219..9610
                     /locus_tag="KR294_003111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBH0241170.1"
                     /translation="MENQQLLGTERISKLLLKYSIPAIIGMLVNSLYNVVDRIFIGNI
                     PGVGPLAITGLGVTMPIMTIILAFGMLIGIGTTTTISIKLGQGKVEEARKLIGNAMTL
                     SVITGIIIMILGILFANKILTLFGASENTLIYAKSYINIILLGTVVNLLSFSLNHSIR
                     ADGSPKISAGIMIVGCLTNIVLDWILIFGFNLGIQGAAIATVTSQALTAILTIGYYIS
                     GKSNLRFSKSNLKLDKKLIKAVFAIGMSPFAMQLAASLVQVISNIALKTHGGDLAIGA
                     MATISSIAMVFLMPIFGINQGAQPIIGFNYGAEKYDRVKKAYLGSLVVATIILCMGMV
                     VVMLFPEAIIGIFNKDPELMNISVNGLRIYLLMLPIVGLSVTGTNFIQSIGKAKMAML
                     LSLLRQVILLIPAVLILPTFLGLQGVWTAQPVSDFIATVITGIVVFRELKRYTPKTEK
                     LNENERLNEITTE"
     gene            9717..10757
                     /locus_tag="KR294_003112"
     CDS             9717..10757
                     /locus_tag="KR294_003112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HBH0241171.1"
                     /translation="MEFTKKSKLKNMYVNMNVARMLSKINEYKGRQLLYKKQPKEILE
                     NLEKKSLVDCSESTYIGNQRDSSNFNLEKLISNEVTPRSREELSIVEYRDVVKTINSA
                     YESIPISSQTILELHGYLYKFSSTRGGSYKSDNDFIEHNLKPSEFISTDSSVNKVEKA
                     VEEICEAYNTLIEEDEIDILILISAFVLDFILIHPFKEGNIKMARVLILLLLNKNGYE
                     VGRYISLGKIFDDSSYEYYSNLNYLKASIGSEKADMNAWIEYFLETILTAYEKLDDSL
                     NISDKKRQTKTSRIEKIINSTLGYFTKEDIRDLCPDIPEPTINRVFNNLRKQDKIEVV
                     ARGRSAKWKKKY"
     gene            11246..11899
                     /locus_tag="KR294_003113"
     CDS             11246..11899
                     /locus_tag="KR294_003113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HBH0241172.1"
                     /translation="MKKKLLYINVNSKPEDLSSSKTVARKFINKFMEKNKDFEVEEID
                     LYKEHIPRLEYQYFEKRNSIVSEENAKNLDDKDRKELTKIRNLCDQFVNASVYVIAAP
                     MWSLSFPAPLKEYIDCIIQDGKTISFEGNDKPQGILNDIDRSMVYIQSSGGHIPWVLK
                     PVMNKGLNYVESIMKFIGIKKFDELLVDGTGTSEEERQAAIEKASEKIDGIIDGMKF"
     gene            11975..12184
                     /locus_tag="KR294_003114"
     CDS             11975..12184
                     /locus_tag="KR294_003114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241173.1"
                     /translation="MREEKSNEKYDCYWCNQENNFCVEIKDNIVMIDDGTGTLKQAVF
                     IGYKQIQINLNCSHCQNLNRIKLNL"
     gene            complement(12324..12890)
                     /locus_tag="KR294_003115"
     CDS             complement(12324..12890)
                     /locus_tag="KR294_003115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HBH0241174.1"
                     /translation="MMNNELNTIILETLNNADITSNDIPSIDLYMDQIISLIDNKLSA
                     NKRFESDKILTKTMINNYSKEGLIKPVKGKKYTKEQILQMIIIYSMKNTLTIQEIKRI
                     LHGVYEKDNFSEKDLVSCYEKFMLIKENQRKNIPDFIESNFENISINPENKDDLLIAL
                     LSLTSMADQLKNISEKLVDRYFPDITKK"
     gene            13051..13704
                     /locus_tag="KR294_003116"
     CDS             13051..13704
                     /locus_tag="KR294_003116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HBH0241175.1"
                     /translation="MYQFFLKGRDPISSLTHFIGACLSLLATIILVFQSVTLQETSLL
                     MIVSVSVFGLSLIALYSASSYYHFLKGTPEQELFFRKVDHAMIYVLIAGSYTPICLNF
                     MEKKEGIIFVTAIWIVAFIGIIIKIFWMDAPRWLSTSIYLLMGWAIVFDINAFNSIPK
                     DCLRLLIMEGVSYSIGAIIYIIKKPNISPEFGFHEIFHIFIMIGSLFHFLAVLLYVL"
BASE COUNT         5479 a         1377 c         2370 g         4757 t
ORIGIN      
        1 ataaaataag agtatatttt atacaatatg aaagctggta ttgcaataga ttaaagcctt
       61 atacacgttt agtttttaaa gaaattagtg ttattatgaa aacctaagtt aatttattaa
      121 ataaataatt gaataaaaaa attttattat gtatttataa aatttttgtt acaaatttgg
      181 cataatatag tatactttaa gtgtgtatta ggttaaatct ataacaaatt agacgtatga
      241 tatagactta gtgtttattg gcatttacaa gaaatttgtt aatatcaact atttgtagtt
      301 tgggcagtta taattattat aggggggatg tccaatacaa aacaatcaac caagaactaa
      361 tattatatta taaagagtta tagttttgtg tgtttatgtt tttaattaaa tttaaagtgg
      421 gaaaaatata tttgttagaa tggagaatag cgagatgagt aataaaatag ttagtaagag
      481 acaattaaca gatagtattt atttaatgga aatagaggca cctagagttg caaaatcttc
      541 tcaaccaggt caatttataa taattaaaaa tgatgaaaaa ggagagagga ttcctcttac
      601 aatagctgac tatgatagag aaaaaggaac agtaactatt gtattccaaa cagttggtgc
      661 ttcaactaaa aagttagcaa tgtttgaaga aaacgatttt gtaatggatt ttgtagggcc
      721 attaggacaa gcaagtgaat ttatacatga agatatagaa gaattaagaa ataaaaagat
      781 attatttgta gctggtggag ttggttctgc tccagtttat ccacaagtta aatggtttaa
      841 agagcatgga ttagatgtag atgtaataat tggtgcaaga actaaagaat taattatatt
      901 agaagatgat atgaaaaaag tagctaaaaa tgtatatgta tcaacagatg atggtacata
      961 tggatttaat ggaagagtta cagacctatt aaaagattta gttgataatc aaggtaaaaa
     1021 atacgaccaa gcaatagtaa ttggaccaat gataatgatg aaatttatgt gccaattaac
     1081 taaagaacta aatataccta ctatagtaag tttaaataca ataatgatag atggaacagg
     1141 tatgtgtggt ggttgtagag ttagtgttgg aaatgaaact aagtttgcat gtgtagatgg
     1201 tcctgaattt gatggtcatt tagttgattt tgatcaagca atgagaagac agtctatgta
     1261 caagactcaa gagggaagag ctatgctaaa acttgaagaa ggcgatagtc atcatcatag
     1321 taattgtgga tgtggaggta acaaataatg gatgctaaaa aagtaaaagt accagttaga
     1381 gaacaagaac ctgctgtgag agcaacaaat tttgatgaag tatgcttagg gtataataaa
     1441 gaagaagcta tggcagaagc taatagatgt ttggcttgta aaaaaccaaa atgtgtgggt
     1501 ggatgtccag taggaatcga cataccaggg tttataacaa aaattaaaga agatgatata
     1561 gaaggtgctg ctaaagtaat agctaagagc agttcattac cagctgtttg tggtagagta
     1621 tgcccacaag aaagtcaatg tgaaggtgta tgtatacttg gaataaaatc agatgctgta
     1681 tcaataggta aattagaaag atttgtagca gattggtcaa aagaaaatga cataaattta
     1741 tctgatacag agcctaagaa aaatcaaaaa gtagcagtaa taggaagtgg tccagcaggt
     1801 ctagcttgtg ctggtgattt agctaaaaaa ggctatgatg taacaatctt tgaagcaatg
     1861 catgagccag gtggagtttt aacttacgga atacctgagt ttagacttcc aaaacaagct
     1921 gttgttcaac ctgaaataga caatataaga aaattaggtg taaaaataga aactaatgta
     1981 attgttggta aaacaattac agtagatgaa cttatagaag atgaaggatt tgaagctata
     2041 ttcataggtt caggagctgg tcttccaatg tttatgaata taccagggga aaatgcaaat
     2101 ggagtatttt ctgcaaatga gtttttaact agagtaaact taatgaaggc ttatagagat
     2161 gattatgata cacctattag ttctggtaaa aaagttgctg tagtaggtgg tggaaatgtt
     2221 gctatggacg ctgctagaac tgcattaaga ttaggttcag aatcatatat agtttataga
     2281 agaagtgaaa aagagcttcc agcaagagct gaagaagttc atcatgcaaa agaagaaggc
     2341 attatattta atacattaac aaatcctaag gaaattttag tagatgaaaa tggatatgtt
     2401 aaaggtatgg tttgtataag aatggaatta ggagagccag atgattctgg aagaagaaga
     2461 cctatagaaa tagaaggttc tgaatttgta cttgatgtag acacagttat aatgtcactt
     2521 ggaacaagcc caaatccact aatatcttct acaacaaaga gtcttgatat aaataagaag
     2581 agatgcttaa taacagatga aaatggtcag acttctaaag agggtgtatt tgcaggtgga
     2641 gatgctgtta ctggagcagc aacagtaata tctgcaatgg gtgctggtaa aacagcagca
     2701 gcatcaatag atgaatattt aaaagcaaaa gttaatgctt aatttgtaaa ttaaagagag
     2761 ggtgtctcaa aatgaacttt ttagttcatg aggcactctt tttgtacaaa atcaaatatg
     2821 ttttaatcat ttcaacaatg aaaatttcat tcctgtagaa agtctaactt ttaggtctta
     2881 gtacaatctc tattttgatg tagccacttt tttagatggt ttaataattt atcagttatt
     2941 attgtaatat ttgatactaa gtaacataac tttgtctaac tatgataaaa tagttataca
     3001 ataaaggtct tgtaaggagt gaataatgtg tggctaataa aatcagattt gtcaaatcta
     3061 acattaaata atagaaaaat aaattgtgta attaatggta ttttaatatg aaaaaaagag
     3121 aaaaagtatt tgatgggcta gtttttaagc atatattaat cttattaata ctattagttt
     3181 tgattgattt aacaagtacc atcatatatg caagtaactc tatggaaatt acttctagaa
     3241 atatgattga ggcatcaaaa agagaacttg aaaactattt agaagtaaac atatctttat
     3301 taaaagctct tagtcaagat gatagatttt ctaatggtga aacatcacta attgaaaagg
     3361 gaaaattatt aagtccatat caaaaggaat ataatctttt tatgattggt ataacagata
     3421 caaaaggaaa tgcttcaagt acatataggg aaaatgttaa ctcaataaaa gataagccta
     3481 gttttgagaa agcaattaaa acaaagcaag tagtagtttc agatattgaa gtcagtaatg
     3541 taacaggtga caaagtattt atcatatatg taccaattgt aaaaaataat gagatgattg
     3601 ggaccatttt tgcttctttt tattttcaag atgtaaataa tttaataagt agaagcaatt
     3661 ttgatgattc tattaaattt ctaatgatag ataaagatta tactattatt tctcatccaa
     3721 acaaaaaata tgtaaatgat aaaagtaaga tgcttgattt agaagggaat attataggaa
     3781 ccactaaaag tgaaatctta aaaaatataa ataaaaaatg tcaaggtgat tttttatctt
     3841 gggataattg gagattatat aatgtaaaat atacgaacat aaagtggact aattggactt
     3901 tagtatcaaa atgtaatata tttaagaact ttaaaaatct aatagttaat tttatgataa
     3961 agttgtattt ttatatagta atatttatga tattgtggaa attaagtaat gctaaattaa
     4021 tagaacaact taaaaaattg gcttattatg attctttaag tggaataaaa aataaagaaa
     4081 agtttagaaa agattctatg tatattttaa agaattatta tcaagataat ttttacttag
     4141 tacaattgga tgtcaataaa tttaaatata taaatgagat gtttggatat gctgaaggga
     4201 ataagatatt aattcatata tcacaggttt taaataataa tacaaataaa tatgaaattt
     4261 gtgctaggat ggataatgac cattttatat tgttgattgc ttgtaacact gaagatgaac
     4321 ttttaaatag attatctaaa ataaataaag aaatttgtaa cttaaatact actaactcat
     4381 ctaagtataa aattgttatg tcaagtggaa tatataagat tactaaaaag gatgatatta
     4441 aaaagattga cttgttaatt gatagagcaa atattgcagc aaaaagtaaa aaggaaaaat
     4501 atgaacattc atattcattt tttaatgaag atacaagaaa tcgattgtac aaggaaaaac
     4561 gattggaaga taatatgaat aaagctttag aaaaaggtga atttatagta tattatcaac
     4621 ctaagtatag tttagatgat gtaaatgaaa ttgaaggagc agaagccttg ataagatgga
     4681 atagtccaga atttgggttt atttcaccta tagattttgt acctttattt gaaaagaatg
     4741 gttttattgt aaatattgat atgttcgtgt ttgaagaagt atgcaaaaca ttaaacaagt
     4801 ggataaataa agggtatact cctgtaccaa tctctgtaaa tatgtctaga gttcatttat
     4861 atagggataa ttttatagaa aatataactg atttgataag taaatacaat atatctcctg
     4921 agtttattga gcttgaacta acagaaagtg ttgtgtttga taatttaaat atattgattg
     4981 atataatgaa aaagattaaa gagataggat tccttatatc aatggatgat tttggttcgg
     5041 gatattcatc tttaaatctg ttaaaagacc tttcttttga tattttaaaa ttagatagag
     5101 gatttttaat cgaaacaaca gatacaaaac gtggaaaaat tattatttct aagattgtgg
     5161 aaatggcaaa agcgattgat attaaagtaa tctgtgaggg cgtagaaact tatgaacaag
     5221 tagagttctt gaaagagata ggttgtgata aggttcaagg atacttattt gctaaaccta
     5281 tggtattaga tgaatttgaa aaacacttaa actttaaatt tgattaatca ttaataatta
     5341 ttagactata agatacccta acaacttact tacaaatatg taagttaatt gttagggtat
     5401 ttttatggtt aaagtagtat attcacgata ttatggtatt gtagtaaaaa taaaaaatta
     5461 tggagaatat aaaatgaaca tattgagtat tagaaatata tcaaaaacat attgtggaaa
     5521 tattccattt aaagcattag ataaggttag tctaaatata gaaaagggag aatttgtgtc
     5581 tgttatggga ccatctggaa gtggtaaatc tactctttta aatataatat ctacagttga
     5641 tagacagagt gaaggtgagg ttgtattaga tggatatgat gtaagtaaat tgaaaggaga
     5701 aaaacttgct gaatttagaa ggaaacaact tggttttgta tttcaggatt ttaatttgat
     5761 tgacacttta actgttggcg aaaatattat gttgccactt acactagagg gggcaagtat
     5821 caaagatatg aatatacaaa ctaaaagtat atctaaattt ttaggaatag ataaaatttt
     5881 agatagaaaa acctatgaaa tttcaggagg tcaagctcaa aggtgtgcta ttgctagagc
     5941 tattataaat aaacctgcca tacttcttgc agatgagcca actggaaatc ttgattcaaa
     6001 atctactgat gatgttttga aattatttac taggataaac aaagaacaaa aggtaacaac
     6061 acttatggta actcatgaag catatagtgc aagttattca gatagagtaa tttttataaa
     6121 agatggttgt atatatacag aaataaaaaa atctgaaagc agtaattctt tctattctga
     6181 tatactagct gttttgtctc aaataggagg tgtaagatag tggattttag aaagtttgct
     6241 tataataata tagttagaaa tttcagggca tatttagcat attttttaag ttctgttttt
     6301 tctataatga tattttttgt ttttgcagtg tctatgttcc atccaattat aacaaaatct
     6361 ggaatgcaga gtggttctac tgcatttatg gctcttatga cttcagaatt aataatattc
     6421 ggttttagtc tactttttat attgtactct ttaggaaatt tcttaaaata tagattgaaa
     6481 gattttggag tattgatgat aattggaatg agtaacagac aactgaaaaa attgatatta
     6541 attgaaaatt tgataatagg atttttagca gtgatgttag gaatattact tggtttatca
     6601 atttcaaaat tgtttttatt gtatttaagc aaactgtttt atatgaattt aactgaattt
     6661 tattttccag taaaagcaat gctattgact attgtatcat ttatgatttt atttttgata
     6721 acaggaccaa tgagcttaaa attattgagt aaaaagagca ttttagagct tttagtaggt
     6781 acaaaaaagc ctaaaaaaga gataaaatct tcaaagctat ttggaataat tggtgtaata
     6841 tgtcttatat taggatatgc tatgatacta tttggcaata agttaaaaat aaatggaggt
     6901 atgtatacaa cagcactatt aattactttg gggatatttt tatttttttc tcaatttact
     6961 attttgatat taaagtattt aaaaaataaa gaaaaatttt ataagaacaa agtaaatatg
     7021 ttacttataa gtaatttgat atataaatta aaggataata cacgattgtt atttttaata
     7081 acaatacttt tatcggctac tttagtagca tttacaacaa cttcaacact tgtaagttct
     7141 caaggagaag cttctaaaaa taatttccca atggtttact catatttttc agagcataat
     7201 aatgaaaaag aatatgaaga actacaacaa attagagaag caatcaaagg atatgattat
     7261 aaggagttaa gttttcctgt acttaaatat aatagggaag tcttactaag tgtaaagaat
     7321 tataacaaat tatcaaagga attgggatta gataaaatta gttcaaagtt agaaaaatat
     7381 gaagggatta taattcctag tagcaattcg caagaacata taaattcttt aaaacaatta
     7441 aaaaattata gtataaaaaa tttaaatata gaagtaaaaa aatcaaaaaa taaaataatt
     7501 tttcctacag gactgtttag taaagttgtg gttataagtg atgacttata caatgaagta
     7561 aaaggtgaat tttcaaaaat taattttcat ggatttgatt ataaaaactg gcaaagcagt
     7621 gcaaagataa ctgaaaattt aaaagaaaaa cattttaatt tggatagaga atataacagg
     7681 tcatattttt taacattacc agatatgtat ttagtagagt tacaacaaag taaaattctt
     7741 caatttatgg gtgtttttat aggagtgata ttatttatag cagtttttag ttttttatac
     7801 ttcagattat atacagacga gatagaagat aatgtaaagt acaaaaaact atcaaaaata
     7861 ggtctatctt ttaaaaatat gaataagatt gttagtatag agataggtac attgtttttt
     7921 ataccgtatt ttatagcaat tataaatagc ataatttctt tactgttttt aaatcaagta
     7981 ttaaataata gttttaagtt agaaaatttg ggtatattac tactgatatc atctatatat
     8041 tcactttatt tttacttatt aaaaaaaaat tatactagaa aagtttggtt ttttgattaa
     8101 agtggtatat aatagatata taaattaata tttaaaaagt agttaatatt aggggagggc
     8161 atttgcacct cccttgtaat atgtggaaaa ttgaatatta gaagaaggag gagacttgat
     8221 ggaaaatcaa caattattag gaacagaacg aattagtaaa ttactactaa aatattctat
     8281 accagctata ataggtatgt tggtaaatag tttatataat gtagtagata gaatttttat
     8341 tggaaatata ccaggggttg gaccacttgc aataacaggt cttggtgtaa caatgccaat
     8401 aatgacaata atacttgcat ttgggatgtt gataggtata ggaactacta ctaccatatc
     8461 aataaaactt gggcaaggta aagtagaaga ggcaagaaaa cttataggaa atgcaatgac
     8521 gttatctgta ataacaggaa ttatcataat gatacttgga atattatttg caaataaaat
     8581 acttacattg tttggagcaa gtgaaaatac tttaatatat gcaaaatcat atatcaatat
     8641 tatattatta ggtacagtag taaatcttct ttccttttct ttaaaccact caataagagc
     8701 tgatggtagt cctaaaattt cagcaggaat aatgatagta ggatgtttaa ctaatatagt
     8761 tttagactgg atattaatat ttggattcaa tttgggaata caaggagctg caattgctac
     8821 agtaacttct caggctctta cagctatttt aactataggg tattatataa gtggaaaatc
     8881 aaacttacga ttcagtaaat ctaatctaaa attagataaa aagctaataa aagcagtgtt
     8941 tgcaataggt atgtcgccat ttgctatgca acttgcagca agtttagttc aagtaatatc
     9001 aaatattgca cttaaaactc atggtggaga tttagctata ggggctatgg ctactatttc
     9061 ttctattgca atggtatttt tgatgcctat ctttggaata aatcaaggag cgcaacctat
     9121 tataggtttc aattatggag ctgaaaaata tgatagggtt aaaaaagcat atttaggttc
     9181 attagtagta gctactataa ttttatgtat gggtatggta gtagttatgc ttttcccaga
     9241 agctattata ggtatattta ataaagaccc tgaacttatg aatatatctg ttaatggatt
     9301 aagaatatac ttacttatgt tgccaattgt aggcttatca gttacaggaa caaactttat
     9361 acaatctata ggaaaagcaa aaatggctat gttattgagc cttttaagac aagtaatttt
     9421 attgatacca gcagtattaa ttcttcctac attcttaggt ttacagggtg tatggacagc
     9481 tcaaccagtg tctgatttta tagctacagt aattacaggt atagttgtat ttagagaatt
     9541 aaaaagatat actcctaaaa ctgaaaaatt aaatgaaaat gaaagactaa acgagataac
     9601 tactgagtaa aaatataaat tcagataatt gagcaagaaa ttgcaaaaaa tacgattata
     9661 tgataaaata aaaccgctgt caaggataag agaaattcta attatggagt gattttatgg
     9721 aatttacaaa gaaaagcaaa ttaaaaaata tgtatgtaaa catgaatgta gctagaatgt
     9781 tgtctaagat aaatgagtat aagggtagac aactgcttta caaaaaacaa ccaaaagaaa
     9841 ttttagaaaa cttagaaaaa aaatctttag tagattgttc tgaatctaca tacattggaa
     9901 atcaaagaga tagtagtaat tttaatctag aaaagttgat aagtaatgaa gttacaccta
     9961 gaagtagaga ggaattgagt attgttgaat acagagatgt ggtaaaaact attaacagtg
    10021 cttatgagag tattcccatc agttcacaaa caattcttga gcttcatgga tacttatata
    10081 aattttcatc tactagagga ggaagttata agtcagataa tgattttatt gaacacaatt
    10141 taaaacctag cgaatttata agtactgatt caagtgtcaa taaagttgaa aaagctgtag
    10201 aagaaatatg tgaagcttat aatacattga tagaggaaga tgaaattgat atattaatat
    10261 taatttctgc atttgtgtta gatttcatat tgatacatcc attcaaagaa ggtaatataa
    10321 aaatggcgag agtacttatc ctattgttac taaataaaaa tgggtatgaa gttggaagat
    10381 atataagttt aggaaagata tttgatgata gttcatatga atattatagt aatttaaatt
    10441 atttgaaagc ctcaataggt agtgaaaaag cagatatgaa tgcatggatt gagtattttt
    10501 tagagacgat attaactgca tatgagaagc tggatgatag tttaaatata tctgataaga
    10561 aaagacaaac aaaaactagt agaatagaga aaataataaa ttctaccctt ggatatttta
    10621 caaaagaaga tataagagat ttatgtcctg acattccaga acctactata aatagagttt
    10681 ttaataatct aagaaaacaa gataagatag aagttgttgc aagaggaaga agtgcaaaat
    10741 ggaagaaaaa atattaaaaa atgtttagat aactaaaatg gtatagtgtt ttacactata
    10801 ccatttttaa tgtcattagc atgagcaata atttaacaac ttaagcaata tcaattttat
    10861 ttattgatta tttttgaact gaaaaatggc gttatatggt atacctcagt ggtaattaat
    10921 tttggatgag aagatataat attacagaat atattaggag tatatgtaga aaaaatataa
    10981 taaaagtgtg aggcttagta attaacaaat tatgtggctt cacacttttt tataaaataa
    11041 agatacttag cagaataata ttttagttga tatgtttata agatggtact tgtttgggta
    11101 aaagtataaa tagtaaaaaa gtagaagtaa tgtgtataaa aacataagtt acattctgta
    11161 ataatagtta ttttataatt caacaaaaga atagaatggg tatatttgtg aaataataat
    11221 ataaaataat cttaggagtg agcttatgaa gaaaaaatta ttatatataa atgtaaattc
    11281 aaaacctgaa gacttatctt caagtaaaac tgtagcaaga aaatttataa ataaatttat
    11341 ggaaaaaaat aaagattttg aggttgaaga gatagacctt tataaagaac atataccaag
    11401 acttgagtat cagtactttg aaaaaagaaa tagcatagtt agtgaagaaa atgctaaaaa
    11461 tttagacgat aaggatagaa aagagcttac aaagattaga aatctttgtg accaatttgt
    11521 gaatgcaagt gtttatgtaa tagcagcacc tatgtggagt ttatcttttc cagcaccact
    11581 taaagagtat atagattgta taattcaaga tggaaaaact atatcttttg aaggcaatga
    11641 taaaccacaa ggaattttaa atgatattga tagaagtatg gtatatatac aatcttctgg
    11701 tggacacata ccatgggtgt tgaagccagt tatgaataaa gggttaaatt atgtggaaag
    11761 tattatgaaa tttataggaa ttaaaaaatt tgatgaattg ttagtagatg gaactggaac
    11821 tagtgaagaa gaaagacaag ctgcaataga aaaagcatct gaaaaaatag atggtataat
    11881 agatgggatg aaattttaat tataatattt tattaaaaat ataaaggaaa aacctctttt
    11941 aatgtagaaa cttatattga aggaggcgag aatcatgcga gaagaaaaaa gtaatgaaaa
    12001 gtatgattgt tattggtgta atcaagagaa taatttctgt gtagaaataa aagataatat
    12061 agtcatgata gatgatggca ctggtacgtt aaaacaagcc gttttcatag ggtataaaca
    12121 aatccaaatt aatttaaact gttcacattg tcaaaactta aatagaataa aattaaattt
    12181 gtagaatttt aaaatggaaa ttattgaagg aattaaaaat agaaagtgtt aatatttaga
    12241 ctgaaaatta tattttatac aataaaagtt tatttaaata acattgtatt ttaatattta
    12301 ttttcagtct tactttatta aaattatttt ttggttatgt ctggaaaata tctgtctact
    12361 aatttttctg aaatattttt taattggtca gccattgaag tcagacttaa taaggctatc
    12421 aataaatcat ctttattttc tggatttata ctaatatttt caaaattaga ctctataaag
    12481 tccggtatat tctttctttg attttctttt attaacatga atttttcgta acatgaaact
    12541 aaatcttttt cactgaaatt atccttttca tacacaccat gtaagattct tttaatttct
    12601 tgtattgtaa gtgtattttt catagaataa ataattatca tctgtaaaat ttgttcttta
    12661 gtatactttt ttcccttaac tggtttgatt aatccctctt tgctgtaatt atttatcatg
    12721 gttttagtaa gaattttatc actttcaaat cttttattag cagaaagctt attgtcaatt
    12781 agagaaataa tttgatccat atataagtca atagatggaa tatcgtttga agttatatct
    12841 gcattattta gtgtttctag tattatagta ttaagttcat tattcatcat atgttacctc
    12901 cataatatat ataatacact aaattagaaa gtaaaacaat attaaggctt gtaaaaaaaa
    12961 cataaagtgg tataattaaa tatataatat agtaatcaaa actatattta tgaatctgat
    13021 ttttaaaata cataattgta ggaggacgaa atgtatcaat tttttttaaa gggtagagac
    13081 ccaataagca gtttaactca ttttataggt gcttgtttat ctcttttagc aactataatt
    13141 ttagtttttc aatctgttac attacaggaa acttctctct tgatgatagt atctgtatct
    13201 gtatttggac tttcactaat tgctttatat agtgcaagtt cgtattatca ttttttaaag
    13261 gggacaccag aacaagaatt gttttttaga aaagtagacc atgcaatgat ttacgtattg
    13321 attgctggct cttatacacc aatatgtctg aattttatgg aaaaaaaaga aggcataata
    13381 tttgttacag caatatggat agttgcattt attggcataa taataaaaat attttggatg
    13441 gatgcaccta gatggttatc taccagtata tatttactta tggggtgggc aattgttttt
    13501 gatataaatg cattcaattc aattcctaag gattgcctta gactattaat tatggaaggt
    13561 gtatcttact ctataggtgc gattatttat ataattaaaa agcctaatat aagtcctgag
    13621 tttggatttc atgaaatatt tcatattttt attatgatag gttctttatt tcacttttta
    13681 gcagttttat tgtatgtttt atagttttaa aagatttgat taattgatac taaaattcta
    13741 caatgaataa aatggaactg ccttatatag attatatctt agacaataag acagttcctt
    13801 attataaata ttaaattcta cttataataa aattttgata aaaatagtcc attcaaaatg
    13861 cctattccat aattccttta atgtactttt catttacgac atatagtttg aatttatgta
    13921 ctataattat atcctctaaa ttctctgaaa cactaacaat tctgacacat ttgtttctaa
    13981 ttt
//
LOCUS       DAEPKC010000105        13772 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.105, whole genome shotgun sequence.
ACCESSION   DAEPKC010000105 DAEPKC010000000
VERSION     DAEPKC010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13772)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13772)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13772
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.105"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            256..669
                     /locus_tag="KR294_003117"
     CDS             256..669
                     /locus_tag="KR294_003117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH0241176.1"
                     /translation="MELEITEKIEKQDEDTIFQGLLKYNLARLEDKNPVDLGIYIRDK
                     AGKIVAGFIGVTHGNWLSIKYLWVSEKLRYKGTGSQLLYKAEKIAKERGCKYVFLDTF
                     SFQAPKFYEKFGYHKVFSLENYPLTGKRYYFRKIL"
     gene            860..2077
                     /locus_tag="KR294_003118"
     CDS             860..2077
                     /locus_tag="KR294_003118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallo-hydrolase"
                     /protein_id="HBH0241177.1"
                     /translation="MLGKKCMDYLQTLGKISSTTNGLTRLILTQEHKKSIDLISSWME
                     GLNLDIEIDDIGNVIGTYKSSFPNAPTLVVASHQDSVKCGGIFDGMLGIIVPLVGLEE
                     AKHNNRSYPFNIKLIAFAEEEGTRFETSLMGSKVFAGTFKEELLKSVDENGITLEEAV
                     TKFGFNTKNLTNLHPRKDVDAYLEFHIEQGPVLENESLPAGIVSSITGFKSFKISVNG
                     KSGHAGTLPMNMRLDAGCCACECVLAIEKVAKTTADLVATVGKMNFYPSSSNVVPERA
                     EFTLDVRSCSQEILDNSVEKIFNEISHICENRKLNYTSELAFENVPVPCSNKITKIIE
                     KSFIDLNLNPFYIYSGAGHDAQEMDNITDIGMVFIRCAGGVSHNPNESVSVDDLDTAV
                     KIFLKILDNLDLK"
     gene            2239..2937
                     /locus_tag="KR294_003119"
     CDS             2239..2937
                     /locus_tag="KR294_003119"
                     /EC_number="5.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid racemase"
                     /protein_id="HBH0241178.1"
                     /translation="MNEKLIGILAGMGPRSTAPFVDLIIDECQSQYGAKYDDEFPKMM
                     IYSLPTPFYIDRPINHELMKETIIDGLQKLESTGVNFIAMPCNSAHIYFKELKESINI
                     PILNIVEETVKKLPTISQKVTLFSTSSTFESTIYQNGIIHNGHEFIFKDEWQIKLNNL
                     IQNIKMDKENPHNIDIWNKLIEDVKNESIENIVIACTDLNVVLEKSYPSINIVDSSKC
                     LAESVVNKYLKLVK"
     gene            complement(3157..3774)
                     /locus_tag="KR294_003120"
     CDS             complement(3157..3774)
                     /locus_tag="KR294_003120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4878 domain-containing protein"
                     /protein_id="HBH0241179.1"
                     /translation="MKKIILALTTFLLAISLTACSSAKPEDTIDSFFNSAKKFDFEGM
                     NKVMENNDEKYKDILKELDTKDPNAQYVLDYLKQNASKITYTIKDSEVKGDKATIKVE
                     CKFIDSTPLLQEIVAEAFTKMIGMSFSGQDLTDEKTTEMLVSIMKEKQKSVKETYVTK
                     NVEFECSKKDNKWIISSVNDAVADVLLSNLVTAGQEFSNSMNTLE"
     gene            complement(3901..4923)
                     /gene="argF"
                     /locus_tag="KR294_003121"
     CDS             complement(3901..4923)
                     /gene="argF"
                     /locus_tag="KR294_003121"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HBH0241180.1"
                     /translation="MNNISLKGKSFLTLKDFTKEEIRYLLTLSSYLKTKKKVGIKGDL
                     LQGKNIALLFEKTSTRTRCSFEVAAHDEGAHVTYLGPNDCHMGKKESVSDTAKVLGRF
                     YDGIEFRGFKQETVESLAKYSGVPVWNGLTDEYHPTQILADFLTVIENVDKDLNKVKF
                     VYVGDARNNMGNSLMIGCAKMGIHFVALAPKELWPNEELVKEMKEIAKKSKGDIMLTE
                     NIDDVKGADVIYTDVWVSMGEEEQYEARINQLKDYQVNMDMIKKTENENVIFLHCLPA
                     FHDLETKVAQEIYEKFGLSELEVTNEVFNSKYSKVFEEAENRMHTIKAVMVSTMTDVN
                     MNNNLI"
     gene            complement(5032..6219)
                     /locus_tag="KR294_003122"
     CDS             complement(5032..6219)
                     /locus_tag="KR294_003122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate aminotransferase family protein"
                     /protein_id="HBH0241181.1"
                     /translation="MNNDNTISKWNEYFIDTYNQPNFVIDYGEGSCFFDTNGNKYIDF
                     TSGYGVSSLGYSNSNLKNALKEQVDKLLHTSNLYFNEPVLYSGEKIINSSGMAKVYFC
                     NSGTEANETAFKIARKYSSDKYGNGRGTIISLKDSFHGRTMMSLMATGMDKYHKYFYP
                     LPEGFKYVERNNIEDLKNNLDSTVCAIILEAIQGEGGVNVLEKDYVLEIVKICQEKDI
                     VVIFDEVQCGIGRTGKLFGYEYFDVKPDIVTVAKGLGAGIPVGGVLVNKKLSKVLGKG
                     DQGTTFGGNLLAMVAASVVLDEISKDGFYNEVLEKGNYIRKSIESFNNKVVLKTKGIG
                     LMIGIETNIESSIIEEKARKKGLLILTAGKNVLRFLPPLTISYKEIDEALEILKDILL
                     EIN"
     gene            complement(6249..7109)
                     /gene="argB"
                     /locus_tag="KR294_003123"
     CDS             complement(6249..7109)
                     /gene="argB"
                     /locus_tag="KR294_003123"
                     /EC_number="2.7.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylglutamate kinase"
                     /protein_id="HBH0241182.1"
                     /translation="MINIEKANTLIEALPYIEKHQGKTIVVKYGGSAMKKDGLKESVM
                     EDLVLMSYVGINIVLVHGGGAEINKMLAKVDIESKFVNGLRYTDEETMEIVKMVLAGK
                     VNKDLVNKIHTKGGKAVGLCGIDNNMILCDPYKNYELGFVGEIKKVNVELIESCLKSG
                     YISVIATIGVGDDGETYNINGDTAASAIAKELNADKLILLTDVPGLLREPDEEKSLIT
                     EVILEDVDKLFEEGIITGGMIPKIEGCVDALNNGVNRVHILDGRVPHSIITELFTDSG
                     IGTLIRKENE"
     gene            complement(7124..8341)
                     /gene="argJ"
                     /locus_tag="KR294_003124"
     CDS             complement(7124..8341)
                     /gene="argJ"
                     /locus_tag="KR294_003124"
                     /EC_number="2.3.1.1"
                     /EC_number="2.3.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate
                     N-acetyltransferase/amino-acid acetyltransferase ArgJ"
                     /protein_id="HBH0241183.1"
                     /translation="MEIIKGGVTVSEGFFASGIHCGLRKNKEKRDLALVYSDVLCDAA
                     AVVTQNKVKGNPVYVTQEHIKNGKAQAIIVNSANANTFNGKEGLINAYKMAKFTSDKL
                     NIKESDVLVASTGVIGKPLNIDLIEENMDELVNNLSKQGHIGAREAIMTTDIIKKEIA
                     VAIMYGDKKITIGGMAKGSGMIHPNMATTLGFITTDANIDGVLLKEALKIAVDKSFNR
                     VSVDGDTSTNDMVMILANGKAKNDRINKKDEHYQVFLSALTYVCIELAKLVAKDGEGC
                     TKLIECYINGALSEAHAVKLAKTVISSSLVKTAVFGADANWGRILCALGYAGEEIDME
                     KVDIIFESMKGYIEVCKNGNGLDFNEEKAKKILEDDEISILVDLNMGNARGNAWGCDL
                     SYDYVRINGSYRN"
     gene            complement(8382..9416)
                     /locus_tag="KR294_003125"
     CDS             complement(8382..9416)
                     /locus_tag="KR294_003125"
                     /EC_number="1.2.1.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyl-gamma-glutamyl-phosphate reductase"
                     /protein_id="HBH0241184.1"
                     /translation="MNKIKVGIIGATGYVGAELIRLLMNHDKVEVTAIGSNSYVGKDI
                     VDIYPSIGYKNNMICIENEKVIDMCDVVFTALPHGVSEKFVIKAIKSKKKVIDLGADF
                     RIKDEEVYSKWYGVSFIDKILHKKAVYGLSEIYKEDIKDADIIANPGCYPTSISLPLM
                     PLLSSKLIKNNNIIIDSKSGLTGAGRELSISSHFTEVNENITAYKIGKHRHTPEIEQN
                     LSESCKEKVSVVFTPNLIPVNRGILSTIYCTKEDNISINDIHRKLTDYYEFKEFIEIL
                     PLDKIASLKNVRFSNKCVISLHENGDTLIICSAIDNMIKGAAGQAIQNMNIIFGIEEN
                     TGLKNIAPSF"
     misc_binding    complement(9670..9883)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(10101..10868)
                     /locus_tag="KR294_003126"
     CDS             complement(10101..10868)
                     /locus_tag="KR294_003126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YoaP domain-containing protein"
                     /protein_id="HBH0241185.1"
                     /translation="MQIIDININNIDNEHICCSISEKKGENCVFSKKAWMKNNFDKGL
                     VFKRFDVRGKAFIEYIPAENAWCPITADNYIFINCFWISGKFKGQGYSNLLLQECVDD
                     AKSKGKYGLVVLSSSKKMPFLSDAKYLKYKDFCLADTSEPNYELLYFPFTDNAPIPCF
                     KNCVKQRKLNENGIVLYYSNQCPHTEKYAPILKKIANSRGIDVNLIKFETAKEAQNAP
                     APFTTYSLFFNGEFVTNEILSEKKIEKFLDTNIKKFN"
     gene            11167..11640
                     /locus_tag="KR294_003127"
     CDS             11167..11640
                     /locus_tag="KR294_003127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH0241186.1"
                     /translation="MFKEYLIRELKEDDIKNALDLIWNVFEEFESPDYCDEGITTFHQ
                     FIEYNSIIEKIKEKTLFFWGCFDSKKLIGVLAIRNLNHICMLFVDKNYHKHGVAKKLM
                     TTGIQYCICNKFNLTEITVNSSPYAVEVYHKLGFKDTAVEQIVDGIRFTPMKLLI"
     gene            complement(12009..12566)
                     /locus_tag="KR294_003128"
     CDS             complement(12009..12566)
                     /locus_tag="KR294_003128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH0241187.1"
                     /translation="MRVSREIVIQATSDIVNKDGLNKVSLKVIAEKLGIRTPSLYNHI
                     ESLDDLLLEVAHKGMREMNSQMIKAAIGNFGDTAIKCISIAYFNFIISNPGVYETIQW
                     ATWHGNNETLEIFDEYKSLLEKLILSCNLNTKNTGEVLNLIMSVLHGYSTLQLGKSFL
                     SKEEAIKGLVDSIDTVLLGIHKKYD"
     gene            12824..13522
                     /locus_tag="KR294_003129"
     CDS             12824..13522
                     /locus_tag="KR294_003129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBH0241188.1"
                     /translation="MEKKYFEIHGVPSILWGNPSSKLYIYIHGQCGNKEEAEAFANIA
                     VPHECQVLSVDLPEHGERKREKNSFNPWHVVPELVSIMEYAKCHWNQISLYANSIGAW
                     FSMLSFEKENLRECIFVSPILDMQQLISNMMLWANVSEEQLKHELIIPTSFGHTLSWE
                     YLQYVKQHPITQWNIPTKILYGKHDELTEIGVVEKFVEKFNCNLTIVENGKHWFNTPQ
                     ELNSLYEWLNTLVK"
BASE COUNT         4713 a         2166 c         1512 g         5381 t
ORIGIN      
        1 ttatgtatta aattaactta ttttaatatt caacaattta ggtttactaa atttattgat
       61 gatttctttt tatataactt aaactacatt tttatttaaa aaaatttaat atcaacaata
      121 taaaattaag aataagtatt attagtttga cattagcata aatgcctatt agaataatgt
      181 taaactatat tctttctact gattttatta aaaaatacca atatacaaaa gattatacaa
      241 ggagaaagtt caaatatgga attagaaatt acagaaaaaa tagaaaaaca agatgaagat
      301 actatttttc aaggattatt aaaatataat cttgctagac ttgaagataa aaacccagtg
      361 gatttaggaa tatatattcg agataaagca ggtaaaattg ttgcaggttt tataggtgtt
      421 actcatggta attggctttc tataaaatac ttatgggtta gtgagaagct tagatataaa
      481 ggtactggaa gtcaactttt atataaggct gaaaaaattg ctaaagaacg aggttgtaaa
      541 tatgtttttt tagatacatt cagttttcaa gcacctaaat tttatgagaa atttggatac
      601 cataaagtat tttcacttga aaattatcct ctaactggaa agagatatta ttttagaaaa
      661 atactataat aataaaaatc atattttata tttttaactt aaaacttctg ctcttcgtct
      721 acagacttta tatttttata tcattattaa tactaaaata gtattttact atacatacaa
      781 aattatttga aagttcaaaa attataagta taaaagctaa tcttagctta aataaaaatt
      841 atatttttag gaggtaaata tgttaggaaa aaaatgtatg gattatctac aaacattagg
      901 aaaaataagt tcaacaacaa atggtcttac aagacttatc ttgactcaag aacataaaaa
      961 atctattgat ttaattagtt catggatgga aggtttaaat cttgatattg aaattgatga
     1021 cattggaaac gttataggta catataaatc aagctttcca aatgctccca cattagtagt
     1081 tgcatctcat caagatagtg taaagtgtgg aggtatattt gatggtatgt taggtataat
     1141 agtgcctcta gttggtcttg aagaagcaaa acacaataat aggtcttatc ctttcaatat
     1201 taagctaatt gctttcgctg aagaggaagg aactagattt gaaacttctt taatgggaag
     1261 taaagttttt gctggtactt ttaaagagga acttcttaaa tctgttgatg aaaatggaat
     1321 tacacttgaa gaagctgtaa caaagtttgg atttaataca aaaaacttaa caaatttgca
     1381 tcctagaaaa gatgtagatg catatttaga atttcatatt gagcagggtc ctgttttaga
     1441 aaatgaatct cttcctgctg gaattgtatc aagtattaca ggatttaaaa gttttaagat
     1501 atcagtaaat ggtaagtctg gacatgctgg tacacttcca atgaatatga gacttgatgc
     1561 tggatgttgt gcctgtgaat gtgtattagc tatcgaaaaa gtagctaaaa cgactgctga
     1621 tttggttgct actgtaggaa agatgaattt ctatccatct tcatcaaatg tggtacctga
     1681 aagagctgaa tttactcttg atgtacgctc ttgttcacaa gaaattcttg ataattctgt
     1741 agaaaagata tttaatgaaa tatcacatat atgtgaaaat agaaaactta attatacaag
     1801 tgaacttgct tttgaaaatg ttcctgtacc atgttctaat aaaataacaa aaatcataga
     1861 aaaaagtttt atagatttaa atcttaatcc tttttatatt tatagtggtg ctggccatga
     1921 tgctcaggaa atggataata taactgatat tggtatggta tttataagat gcgctggggg
     1981 cgtaagtcat aatcctaatg aaagtgtttc tgtagatgac ttggatactg ctgtaaaaat
     2041 atttttaaaa atactagata atcttgattt aaaataattc ttatataaga aagtatatta
     2101 aaatatataa tctaaaaaat cactttatat ttatattata taagtgtaca atataatcta
     2161 ttataaaata taattttatg cttttataga tttttatttt atacataaat atatttatat
     2221 ataaaggaga taatttttat gaatgaaaaa ttaattggta ttttggctgg aatgggtcca
     2281 aggtcaacag ccccttttgt tgatttaatt attgatgagt gtcaatctca atatggagca
     2341 aaatatgatg atgaatttcc aaagatgatg atatattcat tacctacccc attttatatt
     2401 gaccgtccaa taaatcatga acttatgaaa gaaactataa ttgatggatt acaaaagctt
     2461 gaatcaactg gtgtaaattt tattgcaatg ccatgcaatt cagcacatat atactttaaa
     2521 gaattaaaag agtctattaa tataccaata ttaaatattg tagaagaaac agttaaaaaa
     2581 ttacctacta tctcacaaaa agtaactctt ttttcgacta gttcaacttt tgagtctaca
     2641 atttaccaga atggtataat acataatgga catgaattta tatttaaaga tgaatggcaa
     2701 ataaaattaa acaatcttat tcaaaatata aaaatggata aagaaaatcc acacaatatt
     2761 gatatttgga ataaacttat cgaagatgtt aaaaatgaat ctatagaaaa tatagtaatt
     2821 gcttgtactg atttaaatgt agttttagaa aaatcatatc cttcaataaa tattgttgat
     2881 tcatcaaaat gcttggctga atcagttgtc aataaatatc taaaattagt taaataaatt
     2941 tttcatgcac tatattataa aaaatatatg ttataagttt attttaaata gtatagactt
     3001 ataacatata tcatagtttc ttgacaatat agaaattaac catgtatttc attatattaa
     3061 taaaaaggat accaaaaatg gtatccttca taaatattta tatgtttatt tataaaaata
     3121 atcatatatt tattacttta ctacacctaa acaatattat tcaagtgtat tcatagagtt
     3181 agaaaattct tgtcctgctg taacaagatt agataacaat acatcagcta ctgcatcatt
     3241 tactgaactt attatccatt tattatcctt tttagaacat tcaaactcta cattttttgt
     3301 aacataagtc tctttaacgc ttttttgttt ttctttcata attgatacta acatttcagt
     3361 tgttttctca tcagttaagt cttgtcctga aaaactcata ccaatcatct ttgtaaatgc
     3421 ctcagctact atttcttgaa gtaatggtgt tgaatctata aatttacatt ctactttgat
     3481 tgtagcctta tcacctttaa cctcgctgtc ttttattgta tatgtgattt tagatgcatt
     3541 ctgttttaga taatctaaaa catattgggc atttgggtct tttgtatcta attcctttaa
     3601 tatatcctta tatttttcgt cattattttc cattacctta ttcatgcctt caaagtcaaa
     3661 ctttttcgca ctgttaaaaa aactatcaat tgtatcttct ggttttgcac ttgaacatgc
     3721 tgttaaagat attgctaata aaaaagttgt taaagctaat atgatttttt tcatatctca
     3781 aatcctccct cttaatttgt tgatacataa gttattttaa catataatga gagtttttga
     3841 ataatatatt taaaatattt tataaatttt cattaaagta aagtctatat taaaacatat
     3901 ctatattaaa ttattgttca tatttacatc agtcatagta gaaaccataa cagcttttat
     3961 tgtatgcatt ctattttcag cttcttcaaa tacctttgaa tattttgaat taaatacctc
     4021 gtttgtaacc tctaattctg ataatccgaa cttttcataa atctcctgag caaccttagt
     4081 ttctaaatca tgaaatgctg gaagacagtg taaaaatata acattttcat tttcagtttt
     4141 ctttatcata tccatattta cttgataatc tttaagttga tttattcttg cttcatattg
     4201 ctcctcttct cccatagaaa cccatacatc tgtatatata acatctgcac ctttaacatc
     4261 atcaatattt tcagtcaaca ttatatctcc tttggatttc ttggctattt ccttcatttc
     4321 cttaaccaat tcttcatttg gccaaagttc cttaggtgct agtgctacga aatgtattcc
     4381 cattttagca catcctatca tcagtgagtt tcccatatta tttctagcat caccaacata
     4441 tacaaattta actttattca aatctttatc tacattttca attactgtta aaaaatctgc
     4501 cagtatttgt gttggatgat attcatctgt aagtccattc caaacaggca caccagaata
     4561 ttttgctaga ctttcaactg tttcttgttt aaagcctcta aattctattc catcatagaa
     4621 tcttcctaga acttttgctg tatctgatac agactctttt ttacccatat gacaatcatt
     4681 tggacctaga taagttacat gtgctccttc atcatgagct gctacttcaa atgaacatct
     4741 agttcttgtt gatgttttct caaataataa agctatattt tttccttgta gcaaatcgcc
     4801 ttttatacca acttttttct tagtttttaa ataacttgat aaagttaata aatatctaat
     4861 ctcttctttt gtaaaatcct ttaatgtcaa aaaactctta ccttttaaac ttatattatt
     4921 catattaatt cgccccttct tataaacttt ttaaattcaa ttaaacttgt tagcacttta
     4981 cttttttatt tacttctaat ttttatcttt aatcaactat ttcttgaata tttagttaat
     5041 ttctagtaat atatctttta ggatttcaag agcctcatct atttccttat aactgattgt
     5101 taatggtggt aaaaatctca atacattttt tccagcagtc aaaataagca atcctttttt
     5161 tctagctttc tcttctataa tactagattc aatattagtt tcaattccta tcattagacc
     5221 aatacctttt gtctttaata caactttgtt attaaaactt tcaatagatt ttcttatata
     5281 atttcctttt tctaatactt cattataaaa accatcttta gatatctcat ctaatacaac
     5341 tgaagctgcc accatagcta ataaattacc tccaaaagtt gtaccttggt ctccttttcc
     5401 tagtactttt gaaagttttt tatttactaa tactcctcct actggtattc ctgctcccaa
     5461 cccttttgct acggtaacta tatctggttt tacatcaaaa tattcatagc caaaaagttt
     5521 accagttctt cctataccgc attggacttc atcaaaaatc actacaatat ccttttcttg
     5581 acatattttt actatttcca aaacataatc tttttcaaga acattaactc caccttcgcc
     5641 ttgaatcgct tcaagaatta ttgcacaaac tgtggaatca agattatttt ttaaatcttc
     5701 aatattattt ctttctacat atttaaaacc ttcgggaaga ggataaaaat acttatggta
     5761 tttgtccata ccagttgcca ttaaagacat cattgttcta ccatgaaaag agtcttttaa
     5821 acttatgata gttcctctac cattaccata tttgtcacta ctatactttc ttgctatttt
     5881 gaatgctgtt tcatttgctt ctgttccaga attacaaaaa tatactttag ccattccact
     5941 tgaattaatt attttctctc ctgaatacaa cactggctca ttaaaatata aatttgaagt
     6001 atgtaataat ttatctactt gctcttttag agcattcttt aaattactat tactataccc
     6061 aagagaagat actccatatc cacttgtaaa atctatatat ttattgccat tagtatcaaa
     6121 aaaacaactt ccttcaccat aatctatgac aaaattgggt tgattatatg tatctataaa
     6181 atattcattc cattttgaaa ttgtattgtc gttattcatt cttattctcc cctcttaaac
     6241 ttataatttt attcattttc ttttcttatt aatgtaccta ttccactatc agtaaatagc
     6301 tctgttatta tagaatgtgg aactcttcca tccaaaatat gtaccctatt tactccgtta
     6361 tttaaggcat ctacgcatcc ctctatttta ggtatcatac ctccagtaat tataccttct
     6421 tcaaataatt tatcaacatc ctctaatata acttctgtta ttaatgattt ttcttcatct
     6481 ggctctctta acaaaccagg gacatctgta agaagtatca atttatctgc atttaactct
     6541 ttagctatag cagaagctgc tgtgtcacca tttatattat aagtctctcc atcatctcca
     6601 acacctatag ttgcaattac tgaaatataa cctgacttta gacaagattc tataagctca
     6661 acatttactt ttttgatttc tcctacaaat ccaagttcat aatttttata tgggtcacat
     6721 aaaatcatat tattatctat tccacaaagc cctactgctt ttccaccttt tgtatgtatt
     6781 ttatttacta ggtctttatt aacctttcca gcaagtacca tttttacaat ttccatggtc
     6841 tcttcatctg tatatctaag accatttaca aatttacttt ctatatccac ttttgctagc
     6901 atcttattga tttctgcccc tccaccatgt actaaaacta tattgattcc aacataactc
     6961 attaacacaa ggtcttccat aacagattct tttagaccat cttttttcat tgcacttcca
     7021 ccatacttaa ctacaatagt ctttccctga tgtttttcta tatatggtaa agcttctata
     7081 agtgtatttg ctttttctat attaatcatt aaagtatatc ctcctaattt ctataacttc
     7141 catttattct tacataatca tagcttaaat cacatcccca tgcatttcct ctggcattgc
     7201 ccatatttaa atctactaat atacttattt cgtcatcttc aaggattttt tttgcttttt
     7261 cctcattaaa atctaatcca tttccatttt tacatacttc aatatatcct ttcatactct
     7321 caaaaataat atcaactttt tccatatcta tttcttcacc tgcataacct aaagcacaca
     7381 gtattctacc ccaatttgcg tcagctccaa atacagctgt ctttactaat gaagaagata
     7441 taactgtttt tgctaatttt actgcatgtg cttcacttaa tgctccattt atatagcatt
     7501 caattagttt tgtacatcct tctccatctt ttgcaacaag tttagcaagt tctatacaga
     7561 catatgtaag tgcactcaaa aatacttgat aatgttcatc ttttttgttt attctatcat
     7621 tttttgcttt tccatttgct agaatcatta ccatatcatt agtacttgta tctccatcta
     7681 cactaactct attaaaactt ttgtcaacag caatttttaa agcttctttt agcaaaactc
     7741 catcaatatt tgcatctgta gttataaatc ctaacgttgt tgccatatta ggatgtatca
     7801 taccagaacc ttttgccata cctccaatag ttattttttt atctccatac attattgcta
     7861 ctgctatttc tttttttata atatcagttg tcataatagc ttctcttgct ccaatatgac
     7921 cttgtttact tagattattc actaattcat ccatattttc ttctattaaa tctatattta
     7981 atggctttcc tataacacct gtagatgcaa ccaaaacatc actttcttta atatttaatt
     8041 tatcactggt gaatttagcc attttataag catttataag tccttctttt ccattaaagg
     8101 tattagcatt agcactattt actatgatag cttgtgcttt tccattttta atgtgttcct
     8161 gtgtaacata aacaggattg ccctttactt tattttgagt tactactgct gctgcatcac
     8221 ataaaacatc tgaataaacc aaagctaaat ctcttttttc tttatttttt ctcaagccac
     8281 agtgaatccc tgaagcaaaa aatccttctg aaactgtaac tccacccttt ataatctcca
     8341 tatttatcct cctaattata tgagtttagt attttttatt tctaaaatga tggtgcaata
     8401 ttttttaaac ctgtattttc ttcaatacca aatattatat tcatgttttg tatagcttga
     8461 cctgctgctc ccttaatcat attatctata gctgaacaga ttatcaatgt atctccattt
     8521 tcatgtaatg atattacaca tttatttgag aatctaacat tctttaaaga agctatctta
     8581 tctaatggaa gaatttctat aaattcttta aattcataat aatcagttaa tttcctatgt
     8641 atatcattta tagaaatatt atcttctttt gtacaatata tagttgataa gattccccta
     8701 tttactggga ttaagtttgg tgtaaaaact acacttactt tttctttgca ggattcactt
     8761 aaattttgtt ctatttctgg agtatgtctg tgtttcccta ttttatatgc agtgatattt
     8821 tcattaacct ccgtaaagtg actactaatc gataattctc taccagcacc tgtaagacct
     8881 gatttagaat caattattat attattattt tttatcaatt tagaacttag taatggcatc
     8941 aatggtaaag aaatactagt tggataacat ccaggatttg caattatatc tgcatctttt
     9001 atatcttctt tgtatatttc acttaatcca tatacagctt ttttatgtaa gattttatct
     9061 ataaaagata ctccatacca tttactatat acttcttcat cttttattct aaagtcagca
     9121 cctaaatcta taactttctt tttcgattta attgccttta ttacaaactt ttcactaact
     9181 ccatgtggaa gggctgtaaa cacaacatca cacatatcta taactttttc attttctata
     9241 catatcatgt tatttttata tcctatactt ggatatatat caactatatc ttttccaaca
     9301 tacgaatttg aacctatcgc tgtcacttcg actttatcat gattcattaa taatctaatc
     9361 aactctgccc cgacatatcc agttgcacca ataataccaa cttttatttt attcattttg
     9421 ttccctccat ttttatattc aaatagtctt aaaatcctat ctttccactt tactatatga
     9481 taatcatttg ataatacgta gattaaaata ctctaattaa aacaaaaaac cccttagcat
     9541 tataaatact aagaggcgat tttccgcggt accactctta ttggtaaaat tacaataatc
     9601 attaaaactc aaattaaaaa gtatctacaa aatgtacatt taaaattaaa aaagcctctt
     9661 ggtcaaagac caagagacga atatacaccc gcgttaccac tctaattgat aagataatct
     9721 tacccactct aatctcttaa ggcgagattc accaattacc atactattac ttctggtaat
     9781 ctcctccaaa gctctattca caataaaatt cgttactagg cttccaccat tcccagctct
     9841 ctatcaacta gctttatgct actctctttt tcacaggatt tcaatttatt ttcttattgt
     9901 tttatatgat agtttatttt tttaactttg tcaatataat ttttaaattt ttggaaatat
     9961 tttctatatg gttaatttcc agcattttgt atctaaattg cgatataatt tttatatttc
    10021 attcgtcaat ttaaaaaaca tccaaaatat attaaattat aaaataatat attttcaaaa
    10081 tacaatattt acatctcttt ttaattaaat tttttaatgt tggtatctaa aaatttctca
    10141 atctttttct cagaaagtat ctcgttggtt acaaattcac cattaaaaaa aagactgtat
    10201 gtagtaaatg gtgcaggagc attttgtgct tcttttgctg tttcgaattt tataagattt
    10261 acatcaatac ctctagaatt tgcaattttt ttcaaaatag gagcatattt ttccgtatgt
    10321 ggacactgat tactgtaata taaaactata ccattctcat ttaattttct ttgttttaca
    10381 caattcttaa aacatggaat aggagcatta tcagtaaagg gaaaatataa tagctcataa
    10441 tttggttctg atgtatctgc taaacaaaag tccttatatt ttagatattt agcatcagat
    10501 aaaaaaggca tttttttact agacgaaagc acaactaatc catatttacc ttttgatttt
    10561 gcatcatcaa cacactcttg tagcaataga ttagaatatc cttgaccctt aaattttcca
    10621 gatatccaaa aacagttaat aaatatataa ttgtccgcag taataggaca ccatgcattt
    10681 tctgctggaa tatattctat aaaagcttta cctcttacat caaatcgttt aaagactaga
    10741 cctttatcaa aattattttt catccaagct tttttagaaa aaacacaatt ttctcctttt
    10801 ttttcagaaa ttgaacaaca tatatgttca ttgtcaatat tatttatatt tatatcaata
    10861 atctgcatac ttatctcctt ttctaattgc ataataattt ttaaatatat tctatatatt
    10921 tttatcttaa tattttgaat acaacaacat catgtcatat atatttttat tttacataat
    10981 attattttaa gattatctga attattaaat tgtatatata attaaataca ttctatggtc
    11041 taactacact ataatataaa ttatatatta tcataatatt ctaaatttat aaaacaaatt
    11101 gtattgaatt gaatttattt aagatatata attataatta aaataataat aaaggtgttg
    11161 tttataatgt tcaaagaata cttaataaga gaattaaaag aagatgatat taaaaatgca
    11221 ttagacttaa tctggaacgt atttgaagaa tttgaatctc cagattattg tgatgaagga
    11281 attacgacat ttcatcaatt tatagaatat aactctatta ttgaaaaaat caaagaaaaa
    11341 actctcttct tttggggttg ttttgactct aaaaaactta ttggagtctt agctattaga
    11401 aatttaaatc atatatgtat gttatttgta gataaaaact atcataaaca tggtgttgca
    11461 aaaaaattaa tgactacagg catacaatac tgtatttgta ataaatttaa tttaactgaa
    11521 ataactgtaa attcatcacc ttatgctgtt gaagtttatc ataaattagg atttaaagat
    11581 actgctgttg agcaaattgt tgacggtata cgttttacac ctatgaaatt gttaatataa
    11641 taaattaaat aaaaagcaaa gtctcttaaa tattttatag ttactttgct tttaaaccaa
    11701 gatttaaaat aatactatct tttttgtttt ttaataatat actttaaaat ccttactaat
    11761 atgaactata atttattttt tgatatcctt tttgattaac atataaatta attcaattat
    11821 taaacataaa ctatgttgtt tctctttata tctcttcttt gtaaacaata ttgggcattt
    11881 gaaaataaat attcttaaaa tatactgttc tcctgttgat tttcctttgg tacaaatgat
    11941 aaaaatttaa tttacatgcc ccataatgaa gtgttcaata aataagttaa aataatttat
    12001 ttacctcctt aatcatattt tttatgaata cctaataaca cagtatcaat agaatcgact
    12061 aaacctttta tagcttcttc tttactcaaa aatgatttcc caagttgcaa agtcgaataa
    12121 ccatgaagta cactcattat taagtttaat acttcacctg tattctttgt atttagatta
    12181 caagaaagaa taagtttttc taataaggat ttatattcat caaagatttc taatgtttca
    12241 ttatttccat gccaagtagc ccactgaatt gtttcataaa caccaggatt agaaattata
    12301 aaattaaagt atgctatact tatacacttt atagctgtat ctccaaaatt tccaatagcc
    12361 gcctttatca tttgactatt catctctctc attcctttat gagctacttc aagtaataaa
    12421 tcatctagac tttctatatg attgtacaaa gatggtgtac gtattcctag cttttctgca
    12481 ataactttta aagaaacttt gttaagccca tctttattaa ctatatctga tgtagcttgt
    12541 ataactattt ctctactaac acgcatgatt ttccctcttt catttaaaat taattacttt
    12601 attagtttaa ctaatctaat tagtttcgtc aattattgta atttataaaa ttctttatac
    12661 tattataaaa tcttgacagt ttaattataa tttaatataa tactaattaa attagtttta
    12721 atactaatat aattagtatt atattaaatt ctatattaca acattatttt atagtttgat
    12781 taatttaata atcactaata tatcaaactg aaaggagatt tttatggaaa aaaaatattt
    12841 cgaaattcat ggagttcctt caatcctttg gggaaatcct tcaagtaaat tatatattta
    12901 catacatgga caatgtggca ataaagagga ggctgaagct tttgctaata ttgcagttcc
    12961 acatgagtgt caagttttaa gtgttgattt gcctgaacat ggagaacgta aaagagaaaa
    13021 aaattcattt aacccatggc atgttgttcc agaattagta tctattatgg aatatgcaaa
    13081 gtgccactgg aatcaaattt cgttatatgc aaatagcatt ggagcatggt ttagtatgtt
    13141 aagctttgaa aaagagaact taagagagtg tatttttgta tctccaattc tagatatgca
    13201 acagctcatt tcaaatatga tgctctgggc aaatgtatca gaagaacagc ttaaacatga
    13261 actaattatc ccaacttcat ttgggcatac tctttcatgg gaatatctac aatatgtaaa
    13321 acaacatcct atcactcaat ggaatatacc aacaaaaata ttatatggta aacatgatga
    13381 acttactgaa atcggtgttg tagagaaatt tgtagaaaag tttaattgca accttactat
    13441 tgtagaaaat ggcaaacatt ggtttaacac accacaagaa ttaaattcat tatatgaatg
    13501 gttaaatact ttagttaaat aaaaaataat tatattatta atatgattaa attatttata
    13561 aatgttattt aattaatttt attttagcat tattaaaata actacataaa gaataaatta
    13621 gttattatta aagaaattaa aagtatatag agtattaata attttttaat aattagttat
    13681 tatagaaaaa agagggatat aatattgtct ccctctcttt cttctgtaat attatataat
    13741 ttttatttat cactctcaat aaattatagt ta
//
LOCUS       DAEPKC010000106        13729 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.106, whole genome shotgun sequence.
ACCESSION   DAEPKC010000106 DAEPKC010000000
VERSION     DAEPKC010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13729)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13729)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13729
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.106"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(720..1622)
                     /locus_tag="KR294_003130"
     CDS             complement(720..1622)
                     /locus_tag="KR294_003130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HBH0241189.1"
                     /translation="MLPQDYYGLIVILGVILGVMGAFYNWFTLYVQSLYKKIPKIGTF
                     GKLLIPFIMAGILGLVMPDVLGSGHNLVEELTSHEYIFGMVVLIFVIRFIFSAVSFGS
                     GAPGGIFFPLLVLGAFIGGIFGMVGVKVFGMNPDYVNNFVLLAMAGYFTAIVRAPLTG
                     IILIFEMTGSVSQMLSLSVISIVAYIVATLMKSKPIYESLLERLLEKNGEPVHKERGE
                     KILDQFSVMFGSPVANKAIQDVQWPENCLLVAIQRGGEEIIPRGKTILRPSDVIVTMT
                     DERDSGAVYDKMENLCKEHTSHIF"
     gene            complement(1749..1868)
                     /locus_tag="KR294_003131"
                     /pseudo
     CDS             complement(1749..1868)
                     /locus_tag="KR294_003131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(2414..3076)
                     /locus_tag="KR294_003132"
                     /pseudo
     CDS             complement(2414..3076)
                     /locus_tag="KR294_003132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016440163.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
     gene            complement(3236..3772)
                     /locus_tag="KR294_003133"
     CDS             complement(3236..3772)
                     /locus_tag="KR294_003133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrpB family protein"
                     /protein_id="HBH0241190.1"
                     /translation="MIGLKCGMVKLLEHQMIWDKSAKDVIILLKSIWDKTAIDIQHIG
                     STSIPSISAKPIIDIVVGVASLEEAKLYLERLEQCGIVFRGQDVPKQLLFAMGDFEKN
                     TRTHHIHVVEWNGVAWNNYINFRDYLNTFTDKAKLYDSHKQKLALQFEDNRKIYTQRK
                     QELINILLEEARLWRINT"
     gene            complement(3845..4258)
                     /locus_tag="KR294_003134"
     CDS             complement(3845..4258)
                     /locus_tag="KR294_003134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003507530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HBH0241191.1"
                     /translation="MKMPKESIDTIMFAPCGMNCMVCYKHCYHKKPCAGCLNGDTGKP
                     EHCRKCKIKDCVCQKGLFYCFECFNFPCKLIKNLEKSYNKRYQASLMENSKFVQQYGL
                     EKFMQKQKERYTCSKCGGIISIHDRECSECQEKVK"
     gene            4724..5341
                     /locus_tag="KR294_003135"
     CDS             4724..5341
                     /locus_tag="KR294_003135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid stabilization protein"
                     /protein_id="HBH0241192.1"
                     /translation="MDEKILELLQEMQGSISGIEGTISDMQSNINGIEGTISDMQSNI
                     NGIEGTISSMQGNINGIENTISGMQGTIGDMQGSISGMNGTISDMQGSISSMDGTINS
                     MQDSITDMQVEIKEVNSKLDNMEPDIKDLKTGQVETSSRLDTIQSDVTEIKSDVKINR
                     NTLDTVIKHTSSLVKDTSDIKNDLNNIEIVTSKNSNDIAKLKSVK"
     gene            complement(5949..6128)
                     /locus_tag="KR294_003136"
     CDS             complement(5949..6128)
                     /locus_tag="KR294_003136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBH0241193.1"
                     /translation="MLQTGKQGADKKYLDNMFFVKGYVEELLFLDNNYNIVFSCIVFH
                     HCTNVQNIFCIFWKW"
     gene            complement(6354..6887)
                     /locus_tag="KR294_003137"
     CDS             complement(6354..6887)
                     /locus_tag="KR294_003137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HBH0241194.1"
                     /translation="MQYISYYHSPMGNILLASDNIGLTGLWFENQKYYAYNLDQEHQE
                     KELPIFEQTKKWLDIYFSGKEPDFTPSLHMVGTPFQTTVWKILQQIPYGKTITYGEIA
                     YKVAQQKGISKMSAQAIGGAVGHNGISIIIPCHRVVGTNGSLTGYAGGINRKIKLLSL
                     EKVSVQHYFIPKKGSAL"
     gene            7204..7554
                     /locus_tag="KR294_003138"
     CDS             7204..7554
                     /locus_tag="KR294_003138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241195.1"
                     /translation="MGKVRIGCKKEKYFYVRNPVKSLVDRITENEQFAIYHFTHKYNW
                     RNKVFSILQRLIRLEKSKNELYMYEALVSVSFLWLIMIKNIVLPPIKHKNIINIHMQK
                     ILRYIEKYYCFTLY"
     gene            complement(8431..9003)
                     /locus_tag="KR294_003139"
     CDS             complement(8431..9003)
                     /locus_tag="KR294_003139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HBH0241196.1"
                     /translation="MWIYQKTLEHPVNIRQADPRMAKYIMTQLGGPNGELAAATRYLQ
                     QRYTMPTGKSRALLTDIGTEEMAHVEIISSVLYQLIGNCTPEELKAAGLGSNYANFGH
                     GLQPVDSNGVNFTTSYINVFGDSVTDLHEDMAAEQKALATYYQLINLTDDPDLKDILR
                     FLGEREVVHYQRFGEALMDVYEFTECKHQF"
     gene            complement(9065..9328)
                     /locus_tag="KR294_003140"
     CDS             complement(9065..9328)
                     /locus_tag="KR294_003140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat protein CotJB"
                     /protein_id="HBH0241197.1"
                     /translation="MSLNRRELLERISEYQFACIELNLYLDNNPRDKKALDSYNRYCD
                     KFTQAVCDYESKYGALTNFGYESSEYPWSWISEPWPWDKSFYK"
     gene            complement(9328..9549)
                     /locus_tag="KR294_003141"
     CDS             complement(9328..9549)
                     /locus_tag="KR294_003141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat associated protein CotJA"
                     /protein_id="HBH0241198.1"
                     /translation="MGYLKEDKQDYCCEFARPYINRQIYDDTYNPKTALKRGTLFPEL
                     DLIESNNYNDWLYANPKNRVRAKKGGNMY"
     gene            complement(10065..10601)
                     /locus_tag="KR294_003142"
     CDS             complement(10065..10601)
                     /locus_tag="KR294_003142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB-like nuclease domain-containing protein"
                     /protein_id="HBH0241199.1"
                     /translation="MEYKSPVYGIIAVPIEKIESNDYNPNAVAPPEMQLLYKSIKEDG
                     YTMPIVCYYNEEKDKYIIVDGFHRYRVMLENEDIYDRENGLLPVSVIDKSLDERMAST
                     IRHNRARGSHNVDLMSKIITELCEIGKSDEWISKHLGMEVDEILRLKQITGLAYLFKD
                     KEFGNAWIPFGSDIEEEN"
     gene            complement(10619..11932)
                     /locus_tag="KR294_003143"
     CDS             complement(10619..11932)
                     /locus_tag="KR294_003143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3440 domain-containing protein"
                     /protein_id="HBH0241200.1"
                     /translation="MDKRYLESDVFEAFQERLSYLFNEFDYIYVSFSGGKDSGLLLNL
                     VLDYKRKNNISSKIGVFHQDFEAQYSLTTEYVEKVFEDNIEDIEPYWVCLPMATRTAV
                     GNYEMYWYPWDDEKEELWVREMPVKEYIINQKNNPFTYYKYKMRQESLAKQFGRWIRD
                     IHEGAKVVCLLGTRAAESLQRYCSIVNKQHGYKGKCWITKEFKNVWTASPIYDWEIED
                     IWLAHYKFDYDYNKIYDLFYKAGVAPRKMRVASPFNDSAKESLNLYRILDPDVWVKLV
                     ARVQGVNFTSIYGKTKAMGYRSVKLPYGHTWKSFTYFLLDTLPENIRNSYIKKFSTSI
                     EFWQNTGGGLSEIVIRELLRKGYKIELNGVSNHTKDKKSRVIFLDDIPDDTDDIKFTK
                     DIPSWKRMCYCILKNDHMCRFMGFGPTKEQRIRTEYIKKKYEKIH"
     gene            12287..12727
                     /locus_tag="KR294_003144"
     CDS             12287..12727
                     /locus_tag="KR294_003144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3788 domain-containing protein"
                     /protein_id="HBH0241201.1"
                     /translation="MYERMLDKSNKPCLSQIIEYIGKDGYARLCKLETYLKTQYNLSR
                     ELRFPFGNNYGWGYKYSHKSFHLFYAFFEKGAFTVLIQIGDKQVPAVEKTLVALTPKA
                     KELWVTRYPCGNNGGWIKYRILEDADLLDIIQYIRAKKSPPKQN"
     gene            complement(12912..13100)
                     /locus_tag="KR294_003145"
     CDS             complement(12912..13100)
                     /locus_tag="KR294_003145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241202.1"
                     /translation="MNKNNNLVIICMFIGMILGMAIGCAIGISKGNVGITMCYGLIFG
                     MIIGICIGTVIKNSNKKE"
BASE COUNT         4799 a         2397 c         1511 g         5022 t
ORIGIN      
        1 tttactgaaa atcttaaata aagttattct aaagactaat aaaataacta taaaaataca
       61 acttactaaa attgttctaa agatatcatt taaaaatgaa ctaaccacag atactcacct
      121 ttcttatact tttatattta tataatcatc tacacgaata ctaaactgat atgtaggttt
      181 ttaattaact ttgttttcaa taggcgattg tcttgaaagt gttttaaaag ttgatataac
      241 aatgatttag gagtaataag gtcaatttta aaatatgtaa taaaatataa taagcatgaa
      301 acaactgcta tcaagatacc atttccaaac tctataagca aaaggggcta atacaacctt
      361 aacccctttt aattattttc atttataaat aaattctatt cttcccaaaa tatcgcaatt
      421 aaaatatatt aattaaaata tcccagtaag aatatctgaa aaatcttcta cctatttttt
      481 caaacccttt attcccattc ctcatacaat agtgcaactt ttagcacagt ataaatatac
      541 cattagtcca tataatctca ttaacaaata tatacaatta ttttcttcaa actcttttac
      601 atctaagata tcacattttc attttcttat attaattcct taactctctt tcaaattacc
      661 aattttttaa tcaaatcttc attaaatatt ctatcattat taaacattca tcattatccc
      721 taaaaaatat gtgacgtatg ttctttacac aaattttcca tcttatcata cacagcacca
      781 ctatctctct catctgtcat agtcacaatt acatcacttg gtctaagaat tgtcttacct
      841 ctaggaataa tttcttctcc acctctttga attgctacca aaagacaatt ttcaggccac
      901 tgtacatcct gaattgcctt gttcgcaaca ggagagccaa acataacaga gaactggtct
      961 aatatctttt cgcccctctc tttatgtaca ggttctccat ttttttcaag taacctctca
     1021 agaagacttt cataaatagg tttagacttc ataagtgtag ccacaatata tgccacaatt
     1081 gaaattactg atagtgaaag catttgacta acagaacctg tcatttcaaa aattaatatg
     1141 ataccagtca aaggggcacg cacaatagct gtaaaatatc ctgccatagc caaaagcaca
     1201 aagttattta cataatcggg attcattcca aaaactttaa cacctaccat accaaatatt
     1261 ccacctataa atgctcctaa aacaagcaat ggaaaaaata ttccccctgg tgcacctgac
     1321 ccaaaactaa cagccgaaaa tataaaacgt ataacaaaaa tcaaaacaac cattccaaaa
     1381 atatattcat gacttgtaag ttcttcaact aaattgtgtc cactccccag aacatcaggc
     1441 ataacaagcc caagaatacc agccattata aatggaatca acagttttcc aaacgtacca
     1501 attttaggaa tcttcttgta taaagactgc acatatagag taaaccagtt gtaaaatgcc
     1561 cccataactc caagaataac acctaaaatc actattaatc cataataatc ttgtggcaac
     1621 acatttccaa tctgaacctc ccatgactaa agtcacaggg ttcctgcttc atagaatttt
     1681 gcatactaac atatgtctta ctaattctcc acaggctatc cccgtagttc ctacggttct
     1741 tacataagtt atttattttg aattgttatt agtcttaatc cttcttttaa tatatttata
     1801 cttgcattta tatctctatc gtgagtttca ttacaactag gacaaatcca ttctcttata
     1861 ataatgttaa caaatgtaat tatttaaaac aattatttag aaggttttat atttaatttt
     1921 aaataacata tttaagaacc gtaagtctta acttttatca tttttgaggt tgtcgttcac
     1981 ataagttcgc tactacctat gcagttctct tatgaacttc ttacactttc atgcaagcac
     2041 agactatatc ttatccttcg gcattatccg ttaaggtcta cccacttcca ctaccaatag
     2101 cttgtagtgt acttccctca agaggaatag tcgttgaagt ttctcctatt cggagtttac
     2161 ctgctgattg cccattttaa agtacttagg atttaacctt ataccatcta accaattttt
     2221 tctactttcg taactttcac acttaggttt atttcatcct tatgttttag tttggttagc
     2281 tttaggggtt tccagcaatt caagtagtat tggataggtt ctatcctatc tctacatata
     2341 ggtttcccta tatgctgact attttagcta ctaactcatg actaaagtca caagtgtgcg
     2401 tagctatttt ttaatcaaac tggaatacag actccattcc taggaaattg gctgaaatat
     2461 agtctgctgt caaagatgct gtcatcacag aaattaaaac agatactgaa aagtttttat
     2521 ggacttcttc aagtgaaaac ataacacccg ccagtggtgc atgaaaggct gctgataatc
     2581 cagcacttgc cccacaggtt aacaggaatt tttcctctgt cttccctcgg tcaagagctc
     2641 tagaaatacc tttacctgcc atagcaccaa gctgaatgga aggaccttcc cttcccaaag
     2701 caagaccacc catgagtgat aagaatcctc caataaattt tgttggcaac actcgccacc
     2761 atacttgttt tattttccct gtcatttccc cctcaagctg agggatacca cttccagaaa
     2821 tcattggctc ccagtccacc aactttgata caatccatgc aagtactgca agtactgcaa
     2881 accaagctat tatttttatt gtagaacctt ctacaaattt taaaatttgg ctaagccaag
     2941 taccagcctg ccctaaaagt atcctgtata aaagcacaat caaaccagcc acagccccaa
     3001 ccataagtcc ttcaccaatc aaaattacct gaaagtgctc tgcccgtttg ataatatgag
     3061 atgtatcctt tttcatactg ttcctccttc atccaataat tctacacaat ctgaatctcc
     3121 aatgactaaa gtcatgagtg tgtacagata ttttttaatc aacaaaaata gatttttatt
     3181 tactaaatat aagaaaataa ttgctcaatt tctcaataaa tgtaaattta ttcttttagg
     3241 tatttattct ccacagtcgt gcttcttcca gcaaaatatt tattagttct tgctttctct
     3301 gtgtatagat tttacgattg tcctcaaact gtaatgccaa tttttgttta tgactatcat
     3361 agagttttgc tttgtctgta aaagtattta gataatctcg aaaattgata taattattcc
     3421 atgcaacacc attccattca acaacatgaa tatggtgagt acgagtattt ttctcaaaat
     3481 ctcccatagc aaaaagtaat tgttttggta catcctgacc tcgaaaaacg attccacatt
     3541 gctctaacct ttcgaggtat aatttagctt cctctaaaga agcaacacct acaacaatat
     3601 caataatagg ctttgcgcta atactgggaa tagaagtgct tccaatgtgt tgaatatcaa
     3661 tggcagtctt atcccatata cttttcaata atataatgac atcttttgca cttttatccc
     3721 atatcatctg atgttccaat aatttaacca taccacattt taaacctatc actatatacc
     3781 acctcaatat aatccacctt tatatatatt acaatttttt ctctcttgat aaacagtgat
     3841 ttagctattt cactttttct tgacactcgc tacattccct atcatgaata gatataattc
     3901 ctccacattt agaacaagta tatctctcct tctgcttttg cataaacttc tctaaaccgt
     3961 actgctgaac aaatttacta ttttccataa ggcttgcttg atatctcttg ttataacttt
     4021 tttcaagatt ttttatgagt ttacaaggaa aattgaaaca ttcaaaacaa taaaacaacc
     4081 ctttttgaca gacacaatcc tttattttac acttacggca gtgttctggc tttcctgtat
     4141 cgccattcaa acaaccagca catggctttt tgtgataaca atgcttatag caaaccatac
     4201 aattcattcc acaaggagca aacataatcg tatcaatact ctcttttggc attttcataa
     4261 cattttactc ctttcaaaaa tccaatttgt cgaattgtta tatattcata ttgtaacata
     4321 aaaaatagct aaaaaattca tgcactttca ttgccaataa attttcaagg aaatatgaaa
     4381 gtttaaaact aagaataaaa agagataaaa aggaagctac taatcaaatt attcaaatac
     4441 aagtaatcaa tataaataac ttaaggtata tttaaaagta tatgatatta ccagcagttt
     4501 taaatacaaa tataaccaca catgcctcaa aaacacttat tacagtatct tagaaactta
     4561 gacaatacat aagattcatt aataaaaaag ttctcaatat agatatattt aaccatgttt
     4621 tgaatagcag ataatcatat gattaaaaat taaatatgac atagcgtttg tggaatataa
     4681 cacctaaatt atgttataat aataaaacag gagtgtgata gtgatggatg aaaaaatatt
     4741 agagttatta caggaaatgc aaggtagtat cagtggtatc gaaggcacta ttagcgatat
     4801 gcaaagcaat atcaatggta tcgaaggcac tattagcgat atgcaaagca atatcaatgg
     4861 tatcgaaggc actattagta gtatgcaagg caatatcaat ggtatcgaaa acactattag
     4921 tggtatgcaa ggcactattg gcgatatgca aggtagtatc agtggtatga atggcactat
     4981 tagcgatatg caaggcagta tcagtagtat ggatggcact attaatagta tgcaagacag
     5041 tattactgat atgcaagttg aaattaaaga agtcaatagt aagttagaca atatggaacc
     5101 tgatattaaa gacttaaaaa ctggacaagt tgaaactagt agtagacttg atactattca
     5161 gagtgatgtt acagaaatta agtcagatgt aaaaattaac agaaatacat tagatacagt
     5221 gattaaacat acctcttcat tagtaaaaga tacatcagat attaaaaatg atttaaataa
     5281 tatagagata gtcacatcta agaattcgaa tgatattgct aaattaaaat cagttaaata
     5341 atataccata gtaaaaaata cctgaaaatt tcacatactt ctttaaagtt ataccaaatt
     5401 ttatacagaa atactgatta tccgacaaca cactttactt ataaataatt tattaaaaaa
     5461 atactcattt tatcctaaaa ttaacacgac taaatgagtc ttgatataat aataaaaaat
     5521 aagggagatt ggacactaaa aagttgtgta tctcccttat atcctataat atagttatat
     5581 aatttttcag cctaaaataa aagtccatct ttgattaaaa cacatcccct tatcacttat
     5641 aaaaggataa aatcttgttt tcatttttcc atttatatct tcttgcttaa gagtaataat
     5701 tttttctttt gatactttaa gtgtttggtt aaatttaact aatcgactaa gttttgttca
     5761 acatctattt ttcatatttt ccaatactta atctattttt tataaataat tctttcattt
     5821 ctaactcact tacatttttt acataaaacg aaacatataa atttcaacct tatcttgtat
     5881 ggttcttaat acttaatgag tagcttaagt atcaatcatt ataaattttt cccttacatt
     5941 taacactctt accatttcca aaatatacaa aatatatttt gaacatttgt acaatgatga
     6001 aatacaatac atgaaaatac aatattataa ttgttgtcta aaaatagaag ttcttcaaca
     6061 taacctttca caaaaaacat attatctaag tattttttgt ctgctccttg ttttcctgtt
     6121 tgtagcatat aaattacttc ctctaaacat ataactactc acatgaaaaa agaaaataaa
     6181 cttccaaaat acaagctcta aaaactacct ctaaagttgt ataatgttta ctaggaataa
     6241 ggttgtataa catatagttt aaataatcat tttttaaaat tgcaagttat tgctttcaaa
     6301 attagatgtt tgtatatcaa ataaatgatt aagaatttct aaatttaatg gctttataat
     6361 gcactccctt tctttgggat aaaataatgt tgcacagata ctttttctaa agataacaat
     6421 tttatttttc tattaattcc accagcatac ccagtcaaac tcccatttgt tcctacaaca
     6481 cgatgacatg gaataataat agagattcca ttatgcccta ctgcaccacc aattgcttgt
     6541 gctgacattt tagatattcc tttttgttga gcaactttat atgcaatttc tccataagtg
     6601 attgttttac catatggtat ttgttgtaaa attttccaca ctgtagtctg aaaaggagta
     6661 cctaccatat ggagtgatgg tgtaaaatcg ggttcttttc ctgaaaaata aatatctaac
     6721 catttctttg tctgctcgaa aattggcaat tctttttctt gatgttcttg gtcaagatta
     6781 taagcataat acttttgatt ctcaaaccaa agaccagtta acccaatatt atctgatgct
     6841 aaaagaatat ttcccattgg actatggtaa tagctaatat attgcataca attcctcctt
     6901 atattctgaa aacttcactc aaatcattag acacctcttt tctatctacc attatgtaaa
     6961 aacatactaa tataatttcc ttctaactac actttcgtta taatatctat cctcatatca
     7021 tattagtttt atatttacct gcatctgttc atcctttttt ccctttccct ttgatgaata
     7081 taaaattcat acatttaagc ttcctactgt attaactttt atagaagtgt atattataat
     7141 tttatcacta aataggccaa aaaaatatcg atatagcatc aagtaatatc ataatacttt
     7201 caaatgggaa aagtaagaat aggctgtaaa aaagaaaagt atttttatgt tagaaatcca
     7261 gtaaaatcat tagtagatag aataacagaa aacgaacaat ttgctattta tcattttaca
     7321 cataaatata attggcgcaa taaagtattt tctattctac aacgattaat aaggttagaa
     7381 aaaagtaaaa atgaactgta tatgtatgaa gcattagttt ctgtttcttt cctttggctt
     7441 attatgataa aaaatattgt tttgccacca ataaaacaca aaaatataat taatatccat
     7501 atgcaaaaaa ttttacgtta tattgaaaaa tactattgtt ttacattata ttgaagggta
     7561 ctattgtgaa aacttaattt tggagtacta tcaagcagtg gtaatatcaa taaatcagag
     7621 tgctccagat gatttgaact aagtttaaat actatacctt ataaatattt tactgagttt
     7681 tgtttattaa aagcaactca atttctaaaa ggcacaaatg agctaataag tgacattgct
     7741 ataaaagttg tttttcatca aataatctat tttagtaaat gttttaaaga aaaaacggga
     7801 tattctccaa aagtgtacag aaatataaaa aaagagatat gattttttat ttcttttgat
     7861 tatccaaaga gtaaataaaa aatattgtaa aaaacttact aacaacggca atgctttgaa
     7921 ctatggtaat actttgaact tttgattgga ctttttttgc taaaataata tatttaaata
     7981 gcaaagtaat ctgtttaatc aataaaaaat aagagataaa agaaatcaac taaaactttt
     8041 acctcttatt ttgatagttt atcagagcta atatttacac tctttttatt tttgatactt
     8101 cattaaaaat gatgcttatt ctcttttcat ttttaatact tcattagaac ttatgcttat
     8161 tctcttttca cttttaattc ttcattagaa cttatgctta ctctccattc acttttaatt
     8221 cttcattaaa aatgatgctt attctccatt cacttttaat tcttcattag aaatgatgct
     8281 tattctccat tcacttttaa ttcttcatta aaactgatgc ttattctcca ttcactttta
     8341 attcttcatt aaaaatgatg cttattctct gttcactttt aattctttat taaaactgat
     8401 gcttattctc cattcacttt taatacttca ttaaaactga tgcttgcact ctgtaaactc
     8461 ataaacatcc attaatgctt caccaaatct ttgatagtga actacttccc tctcacccaa
     8521 aaatctcaat atatctttca aatcagggtc atcagttaaa tttattaatt gatagtacgt
     8581 agccaatgct ttttgttcag cagccatatc ctcatgtaaa tcagttaccg aatcgccaaa
     8641 gacattaata taacttgtag taaagtttac tccattagaa tctactggct gaagaccatg
     8701 tccaaaatta gcataattac taccaagtcc agcagcctta agctcttctg gagtacaatt
     8761 gcctattaat tgatataaca ctgaagaaat tatctcaaca tgagccattt cctctgtacc
     8821 tatatcagtt aaaagtgcac gagattttcc agttggcata gtatatcttt gttgaagata
     8881 tctagttgca gctgccaact caccattagg tcctcccaac tgagtcatga tatattttgc
     8941 cattctaggg tctgcttgtc ttatgttaac tggatgttcc agtgtttttt gataaatcca
     9001 catattatct tactcctcct taatatatat ttaataataa atctaatttt aaagtttaat
     9061 aattttattt ataaaatgat ttgtcccatg gccaaggttc agatatccat gaccaaggat
     9121 attcacttga ttcatatcca aaattagtta atgctccata tttagattca taatcacaca
     9181 cagcttgtgt aaatttatcg cagtatctgt tgtatgaatc aagagctttc ttatcccttg
     9241 gattgttatc taaatataaa tttaattcta tacaggcaaa ttgatattct gaaattctct
     9301 ctaaaagttc tcttctattt aatgacatta gtacatgtta cccccttttt tagctctaac
     9361 tctattttta ggatttgcat atagccaatc attatagtta tttgactcta ttaaatctaa
     9421 ttcaggaaat aaagtacctc tttttaatgc tgtttttgga ttgtatgtgt catcataaat
     9481 ttgacgattg atgtatggtc tagcaaattc acaacaatag tcttgtttat cctcttttaa
     9541 atatcccatt aattatcctc cttaattttt agaattttaa aatagcatta tttttaaaaa
     9601 ttgtatactg gttctatatt ataactggta gttttaatag gtctttaata agattaaatg
     9661 attaaataag tatctttttt tcttatttta cctctaaaat ttttctaatt aatctttcat
     9721 aaatatctat tttaaataaa taatatagag tttatacaat tttttatagc ttaattacta
     9781 tttactatat attattcatt tttaaataaa atgtgattat tttttattaa aaacgatata
     9841 aatatacaat ttaatactat ttttttataa ataaacttgt attaaaatac atttagttat
     9901 ataattttat tttttctaag agtataatta taaaaataaa aaaagaatag gataattttc
     9961 ctactctttt ttctgtactt acatataata ttaaaactct ttatttttta atatatattt
    10021 taaattttct tttttaataa atctttttct tttaataaat ctatttaatt ttcttcttct
    10081 atatcagagc caaagggaat ccatgcatta ccaaactctt tatctttaaa taaataagct
    10141 aatccagtta tttgcttcaa tctaagaatt tcatcaactt ccatacccag gtgctttgat
    10201 atccattcat cagattttcc aatttcacaa agttcagtta taattttact cattaaatcc
    10261 acattatgag aacctcttgc acgattgtgt cgaatagtac ttgccattct ttcatcaaga
    10321 gatttatcaa ttactgaaac aggaagaagt ccattttctc tatcatatat atcctcattt
    10381 tcaagcatta ctctatatct atgaaaacca tctacaataa tatacttatc cttttcctca
    10441 ttataataac agacaattgg cattgtatac ccatcttctt ttatactttt atacaacaac
    10501 tgcatttctg gtggggctac tgcatttgga ttatagtcgt tagattctat cttttcgatt
    10561 ggcactgcga tgattccata tacaggactt ttatattcca tagcatctta actcctatct
    10621 aatgaatttt ttcatatttc ttcttaatat attccgttct aattctctgt tcttttgtag
    10681 gaccaaatcc cataaatcta cacatatggt cattttttaa aatacaataa cacattcttt
    10741 tccaacttgg tatatctttg gtaaatttaa tatcatccgt atcatcaggt atatcatcca
    10801 aaaatatgac tctactcttt ttatcttttg tatgatttga aactccattt aattctattt
    10861 tataaccttt tctcaacaat tcacgtataa ctatttctga caaaccacca cctgtattct
    10921 gccaaaactc aatagatgtt gaaaattttt taatatagct attccttata ttttcaggta
    10981 aggtatcaag caaaaaatat gtgaaacttt tccatgtgtg tccatatggc aatttaacac
    11041 tacgatatcc catagctttt gttttgccat aaatagaagt aaaattaact ccttgtactc
    11101 tagcaaccaa tttcacccat acatctgggt ccaatattct gtataaattt aaactctctt
    11161 ttgctgaatc attaaaaggt gatgccactc tcatttttct tggagctact ccagctttat
    11221 agaataagtc ataaatttta ttatagtcat agtcaaattt atagtgtgct aaccatatat
    11281 cttctatttc ccaatcatat ataggagatg ccgtccagac atttttaaat tccttagtta
    11341 tccagcactt tcctttatat ccatgctgtt tattcacaat agaacaataa cgttgtagag
    11401 attctgctgc tcgtgttcct aataagcaaa caacttttgc accttcatgt atatctctaa
    11461 tccatctacc aaattgtttt gccaaacttt cttgtctcat tttatattta taataagtaa
    11521 aaggattatt tttttgattt attatgtatt ctttgactgg catttccctt acccataact
    11581 cttctttctc atcatcccat ggataccaat acatttcata atttcctaca gcagttcttg
    11641 tagccattgg taaacacacc caatatggtt caatatcttc aatattatct tcaaatactt
    11701 tttcaacata ttcagtagtc aaactatatt gagcctcaaa atcttgatga aatactccta
    11761 ttttggaact tatattattc tttctcttat aatccaaaac taaatttagc agtaaaccac
    11821 tatcttttcc tccgctaaaa gatacataga tataatcaaa ttcattaaaa agataagaaa
    11881 gtctttcttg aaaagcttca aatacatcgg attctaaata tctcttatcc atttgaatta
    11941 tcccctttca attagaagtt tataaaacct tacaatgcaa tattattatg cttttttagc
    12001 agtaatcagc ataaattata cattatttaa atacacaaat ccaactaact acatataatt
    12061 ataatgtaat tatacttttg tattataaac tatattttat cattatttta catttttttc
    12121 caatatatat aaatatcata tttttctatt agctaaaact aattacttta tatttctacg
    12181 tattagtata ataatacata aaaacttgaa taatgcataa aaacttgaca tactgttgtc
    12241 ataattactt tgctataatt aaaagtaaaa atggaggtaa attctaatgt atgaacgtat
    12301 gcttgataaa agcaataaac cctgtttgtc tcaaataata gaatatatag gtaaagatgg
    12361 atatgcacga ttgtgtaagt tggaaactta cttgaaaact caatataatt tatcaagaga
    12421 acttcgattt ccttttggaa acaattatgg ttggggttac aaatatagcc ataaatcttt
    12481 tcatttattt tatgcttttt ttgaaaaagg tgcatttact gttctgattc agataggtga
    12541 caagcaagtt ccagcagtag aaaaaacgtt ggtagctttg acaccaaaag ctaaagagct
    12601 ctgggtcact cgttatcctt gtggcaataa tggaggctgg attaagtatc gtattttaga
    12661 agatgcagac ttacttgata ttattcaata tataagagca aaaaaatctc cacctaaaca
    12721 aaattaactt ttattttttg tgatttaaat atagtgtata taaattccat tctttccata
    12781 taaaaaaaat aatataaaaa atatctatta gtataactta tttagtatgt cttattctac
    12841 tttttacaga taattaaaaa gttttatcat aaataaatca taactagaca tcctagtaaa
    12901 tcaaaattaa tttattcttt tttattagaa tttttgataa cagtccctat acatatgcca
    12961 attatcattc caaaaattag accataacac attgtgatac ctacatttcc tttagaaata
    13021 cctatagcac aacctatagc cattccaagt atcatgccta taaacataca tataataact
    13081 aaattgttgt ttttattcat agtttttctc cattcaatat attttaaatt gcctagctcg
    13141 ccttcttagc ttaaaacaaa gaaatataaa ttaactttct ttcattctaa tatctgcttg
    13201 tataaatgtc aaacaacaca tttcttgtca taacctcctc tttttgaagt aagtacaatc
    13261 tcccagacgc aataatatca atttcctaaa accatttaag taacttttat atttacataa
    13321 tatttacaat cataaactat attgttattc atttatacat cataaacact ccctcctaat
    13381 cattattata cttaaaataa tgttcattta taataatata tctaacgcac tttaattgaa
    13441 aaaactaaaa ctttgccttt cattcccata tataaataag tatacttttt gatgctctat
    13501 tacaaatcaa ccaaattaat tgatataaat tatcattttc tgttgaaaat accattcgca
    13561 catgctatac ttaattgcat aaatggtaat aaatgtcata tgattttaca aatctattaa
    13621 taacaattat tacttttact gtattttaaa ttttttggac taaatatcaa gaactttcta
    13681 aaatacaaag tacaaaaaat ttatataagt tataaattta tatgaacta
//
LOCUS       DAEPKC010000107        13645 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.107, whole genome shotgun sequence.
ACCESSION   DAEPKC010000107 DAEPKC010000000
VERSION     DAEPKC010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13645)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13645)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13645
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.107"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            29..169
                     /locus_tag="KR294_003146"
     CDS             29..169
                     /locus_tag="KR294_003146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241203.1"
                     /translation="MGIIESASKLAEMVHLLAVEKGITDIEAWDEAVKEYSKIYEERR
                     NE"
     gene            complement(344..664)
                     /locus_tag="KR294_003147"
     CDS             complement(344..664)
                     /locus_tag="KR294_003147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HBH0241204.1"
                     /translation="MKLKTISLPELNNLDPTLESTFIKMGEEQGELAECIGKFRNLSG
                     ENNDLDEVDIIKKTAKELMDVAQTCVTMMFKLEEQYGINLDEIRKEHIKKLEKRGYIK
                     NMDK"
     gene            complement(784..1521)
                     /locus_tag="KR294_003148"
     CDS             complement(784..1521)
                     /locus_tag="KR294_003148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HBH0241205.1"
                     /translation="MDANSLKDLIANHNNIVFFGGAGVSTESNIPDFRSSTGLFSQKL
                     NKQFTAEQLVSHTFFVRYPEEFFEFYKDKLIYPNAKPNNAHIALAKLEEMGKLKAVIT
                     QNIDGLHQMAGSKNVLELHGSVHRNYCTKCGKFFDLESMLNLGGNIPYCDNCGSIVKP
                     DVVLYEEALDSDVITKTISAISNADLLIIGGTSLAVYPAASFIDYYKGDYIALINKAN
                     TVYDKSASLVINKPIGEVLYEAVLRQI"
     gene            1736..3559
                     /gene="acd"
                     /locus_tag="KR294_003149"
     CDS             1736..3559
                     /gene="acd"
                     /locus_tag="KR294_003149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosaminidase"
                     /protein_id="HBH0241206.1"
                     /translation="MKKKAALATLAMLPLGVVNAHADGDIGIVTINYLNVRNEPTAES
                     SIAFVAKKDDKVLIKDSSNGWYKIKAESGQEGWASSKYIAKSNSDSLRTSTNKEKQVI
                     SNSLNMRNGAGTSYRVITVLKKGQKVEVISESNGWSKIKYDGRLGYVSSSYLGDVSNS
                     TNKSKTKQVNTTSLNVRSGPNTSYGLLGKLPKGSKVEVISESNGWSKIKYNGKDAYVS
                     SMYLSDVSQSNSDNSSQSNDKKNTDKVVNTASLNVRSGPGSTYSKLGKVYKGSKVTVL
                     SESSGWAKINFNNKEAFVVGNYLSTSADTSNNNSNSNSDNSSNSNGNNSSSSGQVNGM
                     SGISGAKIDYKSLSYTLESHISKQVEKAASGGNVIAPSNRKSTPSPEFSTFSAQRTSS
                     FVNASSSDIEYYLNPKNFTNTTKGMMQFLKINSYRDGISESSLNSYLNGLSSSVFKNQ
                     GAAFINAAKKYNIDVVYLVSHAMWETAYGKSTLAQGQTLTSYKGQPLSKPVKVYNFFG
                     IGAIDKSANVSGAEAAYSNGWTSVEATIDGSAKWISQNYVNSSKYNQNTIYKMKWNYD
                     YTWHQYATDVNWANGISGIMENLIGLYGGGSSLVFEVPQYK"
     gene            3774..8072
                     /locus_tag="KR294_003150"
     CDS             3774..8072
                     /locus_tag="KR294_003150"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HBH0241207.1"
                     /translation="MESIKEYLDKLEINNSGLGKQLKEVYINRVVYFKEDKIVYFYLT
                     SKDIVSHELLDKFKEELMYKLDYFKDMRMKIRFTGLERKSNKDVIKKYWNNILYILKY
                     LCPSIAGWYKQVEFLCLEEELKIKLPKGIFYERLMKKNVTYVLKTVLSEELGLDLNIT
                     IEKAVDEKVNKERLIRINDREMEEKIRALEIGKVNNCEENEEESYVIKSDVDENLIYG
                     DNANAMIENIVELNASSGTVAVVGDIFDVDTKELKNGKILMIASITDYTSSISCKLFL
                     TDTNKDGVLENVKKGAYLKIKGDIVYDTYQREISMMISGIRKETRIEREDKSEEKRVE
                     LHAHTQMSSMDAICSVKKLVERAAKWGHSAIAITDHGVVQGFPDAMNAGKSNNIKILY
                     GVEGYLVEDDSLIIEDANDKELSQTFVVFDIETTGFSNTNDKITEIGAVKIENFKIVD
                     RFSELINPEKDISYKIQELTGITNELIKDKPTIEEVLPKFMEFVGDSVLVAHNAEFDT
                     GFISQKCREQGLLYNNKKVDTLMLARVMLPNLKRHRLNVVAKELGIPLLNHHRAVDDA
                     EATALIFNKFLQMLTEKGAKTLSDVNNILGKIDYTKLSTNHITLIAKNSIGIKNLYKI
                     ISDAHVNHFFRAPRILRSVLNEYKEGLIIGSACEAGVVFQAVKKNVSDEEMKKIIDLY
                     DYIEVMPIDNNRFMIDKGEVKDEEELRELNRKLIDTAKKFDKIPVATGDVHFLDKHEA
                     VLRKVLKYSQGFKVDEEETYLHFRTTDEMLEEFSYLGEELAYEVVVENSNLIADMVED
                     IKPIPDDTYPPIIEGSDVELREMCYKKAKRIYGDPIPEIVQKRLDRELNSIISNGYAV
                     MYIIAQKLVAKSLSDGYLVGSRGSVGSSFAATMSDITEVNPLPAHYICENEDCKYSFF
                     YEIGEWGSGVDLPDKDCPKCGRKLAKNGHDIPFEVFLGFEGDKEPDIDLNFSGNYQPT
                     IHKYTEELFGEGYVYRAGTIGTVAEKTAFGYARKYVEENNISVPNAEVLRLSNGCTGV
                     KRTSGQHPGGVMVIPDYKDVYDFTPIQYPANDTSCGVITTHFDYHSISGRILKLDILG
                     HDGPTIIRMLEDMTGINITEIPLDDKETMSLFTSTEALGVTPEEINCPIGCLAVPEFG
                     TKFVRQMLLDTKPTTFAELVRISGLSHGTDVWVNNAQDLVREDIVGLKDVISTRDDIM
                     NYLIFKGLPPKMSFTIMESVRKGKGLKPEHIEEMKKNNVPEWYIGSCKKIKYMFPKAH
                     AVAYVMTSFRIAYCKVHYPEAFYATYFTTKVEDFDADLIVKGLDAIKSKINEIESLGN
                     DATTKEKGMLTVLEVALEMYARGIKLLPVDIYKSDATEFIVVGEKTLLPPMAAIQGLG
                     GNAAINIQNERKNGEFISKEDLRKRTKISKTVIETLTNHGSLENMSERNQLSLF"
     gene            8276..8737
                     /locus_tag="KR294_003151"
     CDS             8276..8737
                     /locus_tag="KR294_003151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HBH0241208.1"
                     /translation="MKKNLEATIEEIVTKITDEHGFEMVDVEYVKEAGEYYLRVYIDK
                     EEGISLNECELVSRELSPILDEKDPIKENYFLEVSSPGLDRALKKDRDFVRYQGRDVD
                     LKLYKPLNGCKQFEGELVGLTEDNNIKIIANGKEMEFNRKDVAIVRLAIKF"
     gene            8767..9921
                     /gene="nusA"
                     /locus_tag="KR294_003152"
     CDS             8767..9921
                     /gene="nusA"
                     /locus_tag="KR294_003152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HBH0241209.1"
                     /translation="MNHEFMEALDELVVDRGIDKEILIDTIEQALLTAYKKNFGSAQN
                     VRVEFDRDKGDIKVFSQRVVVDESDLYDTFLEIELADAREINPNYELGDIIEHEVTPK
                     NFGRIAAQTAKQVVVQRIREAEREIVYNEFIEKENEIVTGEVARANKNVVYVNLGRIE
                     GIMTQSEQIPFENYKAGQKIKFYILEVKKTNKGPQIVVSRSHPGLVKRLFEEEVPEIY
                     EGIVQIKSVAREAGSRTKMAVRSIDEKIDPIGACVGPKGLRVKNIVDELGDEKIDIIK
                     YSEDPAEFISAALSPSKVVRVDIDEDEKSALVIVPDYQLSLAIGKEGQNARLAAKLTN
                     WKIDIKSESQAEQEMLNLENSKEIEAEDVEAEFIDQEELDTSEDNFSEEE"
     gene            9928..10209
                     /locus_tag="KR294_003153"
     CDS             9928..10209
                     /locus_tag="KR294_003153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HBH0241210.1"
                     /translation="MILKKVKKVPQRKCIACQDRDSKKELIRIVKNKEGKIFLDPTGR
                     ANGRGAYVCKSSECLKKAIKSKALNKAFKIDVPDEVYDNLLMELEEYEK"
     gene            10199..10510
                     /locus_tag="KR294_003154"
     CDS             10199..10510
                     /locus_tag="KR294_003154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal L7Ae/L30e/S12e/Gadd45 family protein"
                     /protein_id="HBH0241211.1"
                     /translation="MKNNKEKVLSFLGLATRAGKIVSGDDSTLLDLKKGKVNLILIAE
                     DASNNTKKLFKDKSTFRNIPYLFFSTKEEIGFAIGKSPRAVVGIKDENFSKKIIELIE
                     I"
     gene            10532..12472
                     /gene="infB"
                     /locus_tag="KR294_003155"
     CDS             10532..12472
                     /gene="infB"
                     /locus_tag="KR294_003155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HBH0241212.1"
                     /translation="MSKTRVYQIAEELNISNEELINKLAELDINVTDKDSVLEGEELE
                     LALEMLGEDLSQENGNVIEIDGKLTVQVLATKLDKSPSEIIMKLMKMGTMATINQEIS
                     FEIAALAAKDYGFELTVAESDDTEALEIEALMEIEEDKEEDLKPRPPVVTVMGHVDHG
                     KTSLLDAIRKTDVISGEAGGITQHIGASEVKINGHKIVFLDTPGHEAFTSMRARGAQV
                     TDIAILVVAADDGIMPQTVEAINHAKAAGVPLIVAINKIDKPGANPDKVKQELADQGL
                     LVEDWGGEVIAVPVSAKKKEGIDTLLEMVLLVAEMEELRANPNKRAVGTVIEAELDKG
                     RGPVATVLVQGGTLTVGDPIVAGVACGKVRAMINAKGKRVKTAGPSTAVEILGLSEVP
                     QGGDQFVEVPTDKIARSVAARRQQIVRDEMLKSTQRLSLDALFSQMSEGSIKDLNIVI
                     KADVQGSVQAVKQSLEKLSNEEVQVKVIHGGVGAVTESDILLAAASNAIIIGFNVRPV
                     PGAESLGEKENVDIRTYTIIYKAIEDIQAAMTGMLDPEYVDEETGKAEIREIYKISGV
                     GTVAGCYVTNGKIFRNCKVRLVRDSIIIHEGELAALKRFKDDVKEVNSGYECGMSFVN
                     YNDIKEGDIVEAYITKEVERKL"
     gene            12515..12895
                     /gene="rbfA"
                     /locus_tag="KR294_003156"
     CDS             12515..12895
                     /gene="rbfA"
                     /locus_tag="KR294_003156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HBH0241213.1"
                     /translation="MASYNRTRRIAEEIRKVVSTMLINGVKDPRITSMVSVTDVEVTN
                     DLRYAYVYVSILGGDEESTLTGLKSAGGYIRREVGKNIKLRYIPEIVFKLDDSIEKGM
                     YMDSLIKRVNEKNAQQNEDENYDE"
     gene            12876..13553
                     /locus_tag="KR294_003157"
                     /pseudo
     CDS             12876..13553
                     /locus_tag="KR294_003157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438308.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
BASE COUNT         5443 a         1559 c         2574 g         4069 t
ORIGIN      
        1 gtatttgaca atagagaggg tgtaacaaat gggaataata gagtcagcat caaaattggc
       61 tgagatggtt catttattgg ctgttgaaaa ggggataact gatatagaag catgggatga
      121 agctgtgaaa gaatacagca aaatttatga agaaagaaga aatgaataga atgataaaaa
      181 atgaaaactt gatgataaaa aataacttta tttaaagaaa ttcaattttt atagaagtat
      241 taaaaataat ataaataaaa agatggtatt tcaaatgtaa gtaaaaaatc attttgggat
      301 accatcctta ttatttattt taataatata taagtaataa atcttactta tccatatttt
      361 ttatgtaacc tcttttttct aactttttta tatgctcctt acgtatttca tcaagattaa
      421 taccatattg ttcttctagc ttaaacatca tagtaacaca tgtctgcgct acatccatta
      481 gttccttagc agttttcttt ataatatcaa cttcatctaa atcattattt tctccactta
      541 gatttctgaa tttacctata cattcagcta attcaccttg ttcttcaccc attttgataa
      601 atgtagattc tagtgttggg tctaaattat taagctctgg taaagatata gtttttagtt
      661 tcataaaagc tcctttcaag ttattcgtat ttatactaaa acatcataac aaaaataata
      721 ctaaaaaaaa actttaaatt caacataaaa acttacatat ataataaaaa tcatgaaata
      781 aatctatatt tgtcttaata cagcctcata taaaacttct ccaataggtt tatttattac
      841 aagagaagct gacttatcat agactgtatt tgctttatta ataagagcaa tataatcacc
      901 tttgtaataa tctataaaac ttgctgctgg gtacacagct aatgatgtac ctcctataat
      961 caataaatca gcattactta tagcagaaat tgttttagta atgacatcac tgtcaagagc
     1021 ttcctcataa agtactacat ctggttttac tatagaacca cagttgtcac agtaaggaat
     1081 attacctccc agatttaaca tagattctaa gtcaaaaaac ttaccacatt tagtacaata
     1141 atttctatgt acagaaccat gaagttctag cacattttta cttccagcca tttgatgaag
     1201 tccatcaata ttttgagtta tgacagcttt aagcttaccc atttcttcga gttttgctaa
     1261 agctatatga gcattattgg gttttgcatt aggatatatt aatttatcct tataaaattc
     1321 aaaaaattct tctggatatc taacaaaaaa agtatgtgaa actaattgtt cagcagtaaa
     1381 ttgtttattg agtttttggc taaataatcc agtagaactt ctaaagtctg gaatattaga
     1441 ttcagttgaa acacctgctc caccaaaaaa tacaatatta ttgtgattag ctattaagtc
     1501 ttttaagcta tttgcatcca tagttacacc tccaaattat tatatataaa ttgtactaca
     1561 tattaggtcg tttatgtttt attaatttaa ataaatatat agtttaataa gttaaataaa
     1621 gggaatataa ataaaatgta tacagagtat aaatagacaa tatttactaa aataacaagt
     1681 tgtcgtataa ttatattaaa attgttttag tgtataagaa gggcggggga agtacgtgaa
     1741 gaaaaaagca gctttagcaa cattggctat gttaccctta ggtgtggtaa atgcacatgc
     1801 tgatggagat ataggtatag tgactataaa ttatttaaat gtaagaaatg aaccaactgc
     1861 cgaaagtagc atagcctttg ttgctaaaaa agatgataaa gttttgatta aagactcttc
     1921 taatggatgg tataaaataa aagctgaatc tggacaagaa ggttgggctt catcaaaata
     1981 tatagcaaaa tcaaatagtg actctttaag aacgtctaca aataaagaaa aacaagttat
     2041 ttcaaatagt ttaaatatga gaaatggagc aggtacaagt tacagagtaa taactgtact
     2101 aaaaaaaggt caaaaagtag aagtaatatc agagagtaat ggatggtcta aaatcaaata
     2161 tgatggaaga ctaggatatg tatctagctc ttatttagga gacgtttcaa actcaactaa
     2221 taaatcaaaa actaaacaag tgaatacaac ttcactaaat gtaaggagtg gaccaaatac
     2281 aagttatggt ttgttaggca agttgccaaa aggaagtaaa gtagaagtaa tatcagaaag
     2341 taatggatgg tccaaaataa agtataatgg aaaagatgcc tatgtatcta gtatgtactt
     2401 atcggatgta agtcaaagta attcagacaa ttctagtcaa agcaatgata aaaagaatac
     2461 tgataaggtt gtaaatacag cttctttaaa tgtaagaagt ggaccaggtt ctacatatag
     2521 taagttggga aaagtttata aaggaagtaa agtaactgta ctatcagaaa gtagtggatg
     2581 ggctaagatt aattttaaca ataaagaagc atttgtagta ggcaattatt tatctacctc
     2641 agcagatact tcaaataata actcaaatag taactctgat aacagttcta atagtaatgg
     2701 taataattct tcatcatcag gccaagtaaa tggtatgtca ggtataagtg gggctaaaat
     2761 tgattataaa tctttgagtt atactttaga atctcatata agtaaacaag ttgagaaagc
     2821 agcatcagga ggaaatgtga tagctccaag taataggaaa agtactccaa gtcctgagtt
     2881 tagtactttt tcagctcaaa gaacaagctc atttgtaaat gcaagttcaa gtgatataga
     2941 atattattta aatcctaaga attttacaaa tactactaaa ggtatgatgc agtttttaaa
     3001 gattaacagt tatagagatg gtatttcaga atcaagtctt aactcgtatc ttaatggttt
     3061 atcttctagt gtatttaaaa accagggagc agcctttata aatgctgcca agaagtataa
     3121 tatagatgtt gtatatctag tatctcatgc tatgtgggaa actgcttatg gtaagtctac
     3181 acttgcccaa ggtcaaacat taacatctta taagggacaa cctcttagta agccagttaa
     3241 agtatacaat ttttttggta taggagcaat agataaaagt gctaatgttt caggtgcaga
     3301 agcagcgtat tccaatggct ggactagtgt agaagctaca atagatggct ctgcaaagtg
     3361 gatatcacaa aattacgtaa atagttctaa gtacaatcag aatactatct acaagatgaa
     3421 gtggaattat gattatacat ggcatcagta tgcaactgat gtaaactggg ctaatggaat
     3481 ttctggaatt atggaaaatt taattggtct ttatggagga ggaagtagtt tggtttttga
     3541 agttcctcaa tataagtaat acataaataa aaaatataga ctatgggtag ttttcatttt
     3601 atttaaatta tctatagtct ttttgtatat aatttataat ctgtaaattt aatgttaaca
     3661 aaacttttat gttataatat taattctaag taaatataag tgagtaatag gtagaaatag
     3721 ataaaaagtg gtaataatat atataaagat aattttgaga aaggaggata tatatggaaa
     3781 gtattaagga atatttggat aagttagaaa ttaataatag tggtcttgga aagcaactta
     3841 aagaagttta tataaataga gtagtttatt ttaaggaaga taagatagtt tatttttatc
     3901 taacttctaa agatattgtt tctcatgaac ttttagataa atttaaagaa gaattgatgt
     3961 ataaactcga ttattttaaa gatatgagga tgaagataag atttactggt cttgaaagaa
     4021 aatccaataa agatgttata aaaaaatatt ggaataatat attgtatata ttaaagtatc
     4081 tttgtccatc tattgcaggg tggtataaac aagtagaatt tctttgttta gaagaagaat
     4141 taaaaataaa acttccaaaa ggtatatttt atgagcgatt aatgaaaaaa aatgtaactt
     4201 atgtacttaa aaccgtgctt agcgaagagt tgggattaga tttaaatata acaatagaaa
     4261 aagctgttga tgaaaaggta aataaagaaa gactcataag aatcaatgat agagaaatgg
     4321 aagaaaaaat tagggcttta gaaattggaa aagttaataa ctgtgaagaa aatgaagagg
     4381 aaagctatgt cattaagtct gatgtagatg aaaatttaat ctatggagat aatgcaaatg
     4441 ctatgattga aaatatagtt gaattaaatg catcttctgg aacagttgca gttgttggag
     4501 atatatttga tgttgacact aaagaactta aaaacggaaa aatacttatg atagcttcaa
     4561 ttacagatta tactagctca ataagctgta aacttttttt aacagataca aataaggatg
     4621 gagtacttga aaatgttaaa aaaggagcat acttaaaaat caagggtgac atagtttatg
     4681 atacatatca aagagaaatt agtatgatga ttagtgggat aagaaaagaa actagaatag
     4741 agagagaaga taaatcagag gaaaaaagag tagaactcca tgcacataca caaatgtctt
     4801 ctatggatgc tatttgttct gttaaaaagc ttgtagagcg tgcagccaaa tggggtcatt
     4861 ctgctattgc tataacagac catggtgttg tacaaggatt tccagatgct atgaatgcag
     4921 gtaagtcaaa taatataaaa atactttatg gagtagaagg gtacctggtt gaagatgatt
     4981 ctctcattat agaggatgca aatgataaag aactttcgca gacatttgtt gtatttgaca
     5041 tagagacaac tggcttttct aatacaaatg ataaaataac tgagattggt gctgtaaaaa
     5101 tagaaaactt taagattgta gatagattta gtgagttaat aaatcctgaa aaagatattt
     5161 cttataagat acaggaattg acaggaataa ctaatgaatt aattaaagac aagccaacca
     5221 ttgaagaagt tcttcctaag tttatggaat ttgttggaga tagtgtatta gtagcacata
     5281 atgcagagtt tgatactgga tttatatcgc aaaaatgtag ggaacaaggc ttgttatata
     5341 ataacaaaaa agtagataca cttatgttag caagagtaat gttgccaaac ttaaaaagac
     5401 atagattaaa tgtcgttgca aaagaacttg gtattcctct tttaaatcac catagagcag
     5461 tggatgatgc tgaagctaca gcacttatat ttaataagtt tttgcagatg cttacagaaa
     5521 aaggtgcaaa aactctaagt gatgtaaaca atatacttgg aaagattgat tacacaaagc
     5581 ttagcacaaa tcatataacc ttgatagcaa aaaattctat aggtataaaa aatttatata
     5641 aaataatttc agatgcacat gtaaatcatt tttttagagc accaagaatc cttagaagtg
     5701 tattaaatga atataaagaa ggattaataa ttggttcggc ttgtgaagct ggggtggttt
     5761 ttcaagctgt aaagaaaaac gtgtctgatg aggaaatgaa aaaaataata gatttatacg
     5821 attatattga agtaatgcct atagataata atagatttat gattgataaa ggagaagtaa
     5881 aggacgaaga agagttaagg gagttgaata ggaaactaat tgatacagcc aaaaaatttg
     5941 acaaaattcc agtagctact ggggatgttc attttttaga caaacatgaa gctgtcttaa
     6001 gaaaagttct taaatattct caaggtttta aagtagatga agaagaaact tatttacatt
     6061 ttagaacaac agatgaaatg ttggaagagt ttagttatct tggagaagaa ttggcatatg
     6121 aagttgtagt tgaaaatagt aatctgattg ccgatatggt tgaagatata aaacctatac
     6181 cagatgatac ttatcctcca attatagagg gctcagatgt ggagttaaga gaaatgtgtt
     6241 acaaaaaagc caaacgaatc tatggagacc caataccaga aatagttcaa aaaagactgg
     6301 atagagaatt aaattcaata ataagcaatg ggtatgcagt tatgtatatt atagctcaaa
     6361 aactggttgc aaaatctctt tcagatggat atttagttgg ttcaagaggc tcagttggct
     6421 catcttttgc agctactatg agtgatataa cagaagttaa tcctcttcca gcacattata
     6481 tttgtgaaaa cgaagactgt aaatattcat tcttttatga aataggtgaa tggggctcag
     6541 gtgttgattt accagacaag gattgtccaa agtgtggaag aaaacttgct aaaaacggtc
     6601 atgatattcc atttgaggtt ttcttaggtt ttgaaggtga taaggaacca gatatagact
     6661 taaatttctc aggaaattat cagccaacaa ttcataaata cacagaagaa ctatttggag
     6721 aggggtatgt atatagggct gggactatag gtactgtagc agaaaaaaca gcttttggat
     6781 acgcaagaaa atatgtggaa gaaaataata taagtgtacc aaatgcagaa gtacttaggc
     6841 tttcaaatgg atgtactgga gtaaaaagaa cctcaggaca acatcctggt ggagttatgg
     6901 ttataccaga ctataaagat gtatacgatt ttacacctat acagtatcca gcaaatgata
     6961 cttcttgtgg tgttataact actcactttg attatcattc aataagtggt agaatactta
     7021 aacttgatat acttggacac gacggtccta ccattataag gatgcttgaa gatatgactg
     7081 gaataaatat aacagaaatt cctttagatg ataaagagac tatgtctcta tttacatcta
     7141 cagaagcatt aggtgttaca ccagaagaaa taaactgtcc tataggttgc cttgctgtac
     7201 cagagtttgg aactaagttt gtacgacaaa tgttacttga cacaaaacct actacatttg
     7261 cagaacttgt acgtatatct ggtctctctc atgggacaga tgtttgggta aataatgcac
     7321 aagacttagt tagagaagat atagttggat taaaagatgt tatatctaca cgagatgaca
     7381 taatgaacta tttaatattt aaaggattac ctcccaaaat gagctttaca ataatggaga
     7441 gtgtaagaaa aggtaaaggt ttaaaaccag aacacattga agaaatgaaa aaaaataatg
     7501 ttccagaatg gtatataggc tcatgtaaaa agattaagta catgttccca aaagcacatg
     7561 ctgttgctta tgtaatgaca tcatttagaa ttgcatattg taaagttcac tatccagaag
     7621 cattttatgc gacttatttt acgacaaaag ttgaggattt tgatgcagat ttaattgtta
     7681 aaggattaga tgctataaaa tcaaaaataa atgaaattga gtcactggga aatgatgcaa
     7741 ccacaaaaga aaaaggtatg ttgaccgttt tagaagttgc tcttgaaatg tatgctagag
     7801 gaataaaatt attaccagtt gatatatata aatcagatgc aactgagttt atagttgtag
     7861 gagaaaaaac attacttcca ccaatggcag caatacaagg tcttggagga aatgcggcta
     7921 taaacatcca aaatgaaaga aaaaatggtg aatttatatc aaaagaagat ttgagaaaga
     7981 gaacaaaaat atcaaaaacg gtaatagaaa ctcttactaa tcatggttca cttgagaata
     8041 tgagtgagag aaatcaattg tcattgtttt aagttagccc aaaaagttgc aaataaaaga
     8101 attttatgat atcatagtat agaaaatagt atactttgca gaaactaaga gtgagacagc
     8161 tgttctcact cttttatttt aaatatatta ttaaaaagct ggtttatttt tattaaatat
     8221 attttattta agattatata aactggtcat ttacaattga ataggaggaa ctttaatgaa
     8281 aaaaaattta gaagctacaa ttgaggagat tgtaactaaa ataacggatg aacatggatt
     8341 tgaaatggtt gatgttgaat atgtaaaaga agcaggagaa tactacttaa gagtatacat
     8401 agataaagaa gaaggaatat ctttaaatga atgtgaatta gttagtagag aattaagtcc
     8461 aatactagat gaaaaagacc ctataaaaga aaattacttt ttagaggtat cttctccagg
     8521 gcttgataga gcattaaaaa aagacagaga ttttgttaga tatcaaggta gagatgtaga
     8581 tttaaaatta tataaaccat taaatggatg taagcaattt gaaggtgaac ttgtaggatt
     8641 aacagaagat aataatataa aaatcattgc aaatggtaag gaaatggaat ttaatagaaa
     8701 agatgttgct attgtcagat tagcaataaa gttttagtgg tatattaaat agggaggata
     8761 taaaaaatga atcatgaatt tatggaagca ttagatgaat tagtagttga cagaggtata
     8821 gataaagaaa tacttataga tactatagaa caagctcttt taactgcata caagaaaaac
     8881 tttggttcag cacaaaatgt tagagttgaa tttgatagag acaagggaga tataaaagta
     8941 ttttctcaaa gagttgttgt tgatgaatca gatttatatg atactttctt agaaatagag
     9001 ttagcagatg ctagagagat aaatcctaat tatgaattag gtgatattat agaacatgaa
     9061 gttacaccta aaaactttgg aagaattgca gctcaaacag caaagcaagt agttgttcaa
     9121 agaataaggg aagctgagag agaaatagtg tataatgaat ttatagaaaa agaaaatgaa
     9181 atagttacag gagaggttgc tagagcaaat aaaaatgttg tttatgtaaa tcttggaaga
     9241 atagaaggta taatgactca aagtgaacaa ataccatttg agaattataa agcaggtcaa
     9301 aaaataaaat tctatatact tgaagttaaa aagactaaca aaggacctca aatagttgta
     9361 tcaagaagtc atccgggtct agtaaagaga ttgtttgaag aagaagttcc tgaaatatat
     9421 gaaggaatag ttcaaataaa atctgtagca agagaagcag ggtcaagaac taaaatggca
     9481 gtaagatcta tagatgaaaa aatagaccca attggagctt gtgttggacc aaaaggactt
     9541 agagtaaaaa atatagtgga tgaacttggc gatgagaaaa tagatataat aaaatatagt
     9601 gaagacccag cagagtttat atcagcagca cttagcccat caaaggttgt tagagtagat
     9661 atagatgaag atgaaaagtc tgccttagta atcgttccag attatcagtt atcgcttgct
     9721 ataggtaaag aaggtcaaaa tgcaagacta gcagcaaaat tgactaactg gaaaatagat
     9781 attaagagcg aatctcaagc agaacaagaa atgttaaatc ttgaaaattc caaagaaata
     9841 gaagctgagg atgttgaagc tgaatttatc gaccaagaag agttagatac ttcagaggat
     9901 aattttagtg aagaagagta aggagggatg attttgaaaa aagtaaaaaa agtgcctcaa
     9961 agaaaatgca tagcatgtca agatagagac tctaaaaaag agcttataag aatagttaaa
    10021 aataaagaag gaaaaatatt tttagaccca acaggaagag ccaatggaag aggagcatat
    10081 gtatgtaaaa gctctgaatg tctaaaaaaa gctataaaga gtaaagcatt aaataaagct
    10141 tttaaaatag atgttcctga tgaagtctat gataatctac ttatggagtt agaagaatat
    10201 gaaaaataat aaagaaaaag tactttcgtt cttagggctc gcaactcgtg cagggaaaat
    10261 agtgtctggt gatgattcaa ctttgcttga ccttaaaaaa ggaaaagtaa atttgatttt
    10321 aatcgcagaa gatgcatcaa ataatactaa aaaacttttt aaagataaat caacttttag
    10381 aaatattcca tatctatttt tttcaacaaa agaggaaata ggatttgcaa taggaaaatc
    10441 tccaagagca gttgtaggaa taaaagatga aaatttttct aaaaagataa ttgaactaat
    10501 agaaatttaa aataaaatag ggggtgatct tgtgtcaaaa acaagagtat accaaatagc
    10561 agaagaatta aatatatcaa atgaagagct tataaataag ttagctgaat tagatataaa
    10621 tgtaactgac aaagattcag tattagaagg tgaagagtta gaattagcac ttgaaatgtt
    10681 aggtgaagat ttatctcaag aaaatggaaa tgttatagaa atagatggaa agttgacagt
    10741 acaagtatta gcaacgaaat tagataaatc tccatcagaa ataattatga agcttatgaa
    10801 aatgggaact atggcaacaa taaatcaaga gataagtttt gagattgctg ctttggctgc
    10861 caaagactat ggatttgaat taacagtagc tgaaagtgat gatacagaag ctttagaaat
    10921 agaagcttta atggaaattg aagaagacaa agaagaggat ttaaaaccta gaccaccagt
    10981 tgttacagtt atgggacatg ttgaccatgg taagacatct ttactagatg caataagaaa
    11041 aactgatgtg atctcaggtg aagctggagg aataactcag catataggtg cttcagaagt
    11101 taaaatcaat ggacacaaaa tagtattttt agatactcca ggacatgagg ctttcacatc
    11161 aatgagagca agaggagcac aagttacaga tatagcaata ttagtagttg cagcagatga
    11221 tggtataatg cctcaaacag ttgaagctat aaaccatgct aaagcagcag gtgtaccttt
    11281 aatagttgct attaataaaa tagataaacc aggtgcaaac ccagataagg ttaaacagga
    11341 attagcagac caaggattat tagttgaaga ctggggtgga gaagtaatag cagttccagt
    11401 atcagctaag aaaaaagaag gaatagatac acttttagaa atggtattat tggttgctga
    11461 aatggaagag ttaagagcta atccaaataa aagagcagta ggaactgtta tagaagctga
    11521 gcttgataaa ggaagagggc cagttgcaac agtacttgtt caaggtggta ctttaacagt
    11581 aggtgaccca atcgttgcag gtgttgcatg tggtaaagtt agagcaatga taaatgcaaa
    11641 aggtaagaga gtaaaaacag caggaccatc tacagcagtc gagatattag gtctatcaga
    11701 agttccacaa ggaggagacc aatttgtcga agttccaact gataagattg ctagaagtgt
    11761 agcagcaaga agacaacaaa tagttagaga tgaaatgtta aaatcaactc aaagattatc
    11821 actagatgct ctatttagtc aaatgagtga aggttctata aaagacctta atatagttat
    11881 aaaagcagat gtacaaggtt cagtacaggc agttaaacaa tctttagaaa aattatcaaa
    11941 tgaagaagtt caagttaaag taatacatgg tggtgttgga gctgtaacag aatcagacat
    12001 attacttgca gcagcttcta acgcaataat aataggattc aatgtaagac cagttccagg
    12061 tgcagaatct ctaggagaaa aagaaaatgt tgatataaga acatatacta taatatacaa
    12121 ggcaatagaa gatatacaag cggctatgac tggtatgtta gaccctgaat atgttgatga
    12181 agaaacagga aaagctgaaa taagagaaat atataaaata tctggtgttg gaacagtagc
    12241 tggatgttat gtgactaatg gtaagatatt tagaaattgt aaagtaagat tagttagaga
    12301 tagcataata atacatgaag gtgagcttgc agcacttaag agatttaaag atgatgtaaa
    12361 agaagttaat tctggatacg aatgtggtat gagttttgta aattataacg acataaaaga
    12421 aggcgatata gtagaagctt atataactaa agaagtagaa agaaaattat aaattcgtat
    12481 caaagaaaat cagttagtaa agaaggtcga tggtatggca tcatataata gaacaagaag
    12541 gatagcagaa gaaataagaa aagtcgtaag tactatgctt ataaatggag taaaagaccc
    12601 tagaataaca tctatggtga gtgtaactga tgtagaagtt acaaatgacc taagatatgc
    12661 ttatgtatat gtaagtattc taggcggaga tgaagaatcc acactaacag gtcttaaaag
    12721 tgctggagga tatataagaa gagaagtagg aaaaaatata aaacttagat atattcctga
    12781 gatagtattt aaacttgatg attcaataga aaaaggaatg tatatggata gccttataaa
    12841 aagagttaat gaaaaaaatg ctcaacaaaa tgaggatgaa aattatgatg aataatatgg
    12901 atagtattat aaactatatt tatgagggtg actattttat agttacctct catatcagtc
    12961 cagatggaga caatattggt tctacacttt caatgtatta tacattgaag aatttaggaa
    13021 aaaatgtata ttatgtactt gatgatgaag ctccattaaa tttaaggttt ttggttgaag
    13081 gtgtaaaaat ctataagtct aatgaattta atatgaagaa ctattctcta attgcacttg
    13141 attgtgggga taagatgaga atatgtgtga gtgatgaaat caaaaataat gcatcaaaat
    13201 taatctgtat tgaccatcat gctagtaatg attcatatgg agatttaaat tatgtagata
    13261 ttgatgcatc ttctacatgt gaattagttt ataatttatt agttagattt cagcaaataa
    13321 aagatattaa tattataaat gaagatatag caacatgttt atatacaggt cttgtaactg
    13381 atactggaaa cttttcgtat tcaaatgtac atgcaagtag ctttgaaatg gcaaaaaatt
    13441 tacttgtttt aggtgcacaa aaaaatacta taatacaaaa tatatatcaa agcaattctt
    13501 ctggttatta caaattatta ggagaagctc taaagggttt ggagatattt gattaaaaaa
    13561 tagttacgca cactcgtgac tttagtcatg agttagtagc taaaatagtc agcatatagg
    13621 gaaacttata tgtagagata ggata
//
LOCUS       DAEPKC010000108        13610 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.108, whole genome shotgun sequence.
ACCESSION   DAEPKC010000108 DAEPKC010000000
VERSION     DAEPKC010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13610)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13610)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13610
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.108"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            210..3113
                     /locus_tag="KR294_003158"
     CDS             210..3113
                     /locus_tag="KR294_003158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH0241214.1"
                     /translation="MELRDKLVNIINTENKKDPLTDVQIAKFLSTTRENITNLRKELN
                     ISNSRQRRYPYLKSAISAILQKNKNISVSEITRELMTEGFNISRRVVEELLPKESLEM
                     DVVEESEEESNDPFETLIGNKGSLRNAVEQAKSAILYPPKGLPTLIIGESGVGKSLFS
                     RHMYEFAKQKKIVKESSNFVVFNCADYSDNPQLLLSLLFGYKKGAFTGAEYDTPGLVE
                     EADEGVLFLDEIHRLPPKGQEILFSILDRGKFRRLGETNAERKVSIMLIGATTENVET
                     NLLLTFRRRIPMLITLPPLHDRLLKEKIDLIYNIFQQECNRINAKIFVDKNVIEILAL
                     KKFSGNIGQLQNMIQVLCARAFMKFINSKDEDSESIVVVDINEVLKLKDSFKDAAFQE
                     IEYTEIRKYLKNAIFIPFNLEESSVKGSLLSDEYILPEDIYKTIEKKYYDLKSLDIED
                     IDIENILWTFILNRFADLKFNLDSNEEIFSMSDLNSFVSDSLVKLVKELMNDIVEKNM
                     NLEVNKNMFKYLAIHLEEAIKRIKLNQKIINVNLEKIKIDFSKEYEISKSFAIKIEES
                     IGIKIPDDEIGFITLYIKSALKNEVKKDKVGLIIISHGRIATETVNVVKELLGVKFPV
                     AIDMPLDEKPINIYNKAVELSKIIDQGKGILFLVDIGSLTNIGQIVNKRTNISTKTID
                     RVDLLMALEATRKVSMGEEELDEIFFSLLKDRMGYNYELEKHIDKSNAIVTLCLTGEG
                     TAKYISKTLEEKYDNTKCYQMSALDENLFCKIENLKETNNILAIVGTINPKIPGINFI
                     PYNKELFKNLDIYLSKSKQQDDRPVKSYERMLDEDLVIFEPDIYFKKDLLEYVCSILI
                     NKEYVEKDYLDSVLHREEMLPTYSKGAIGVPHGDSSTVNSTRFVFVKLKNPIDWGVGN
                     VNFIFMPVFQANDKEIVKNVLEILKDAEFMNNANKCFDKDAFRRIIFDKFKHL"
     gene            3146..3592
                     /locus_tag="KR294_003159"
     CDS             3146..3592
                     /locus_tag="KR294_003159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH0241215.1"
                     /translation="MNVDLISLGLESNDYESVIEELGSIMCKKEYVKETYINAVLERE
                     RTLPTGLDIGEMCVAIPHTDSKHVNESNVAVGILKNPVKFNSMIDPKDRLDVELVFLL
                     AVKNPDSQVKLLKDLMSVFQNIKLLKNIKNASTKEEVAKLLDFIEI"
     gene            3715..4017
                     /locus_tag="KR294_003160"
     CDS             3715..4017
                     /locus_tag="KR294_003160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH0241216.1"
                     /translation="MKQFNVLSVCGSGTVTSSMVAGKLKEVLGNKGISITTTEARPTE
                     ALNLAQSGRFDFITFTSPLQTGDYGIPTINAFACLTGIGEEAFFEEVLTVIEGIDK"
     gene            4198..5604
                     /locus_tag="KR294_003161"
     CDS             4198..5604
                     /locus_tag="KR294_003161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HBH0241217.1"
                     /translation="MLEFMKSIIDTFGSAIIVPIIIFIIAKIFKVTTKKSFLSAVYAG
                     VALQGFTLILNSFTPIITPVINRMVESTGVNLPVFDVGWQATSLVAFSTSAGMIYLGL
                     GILLQTILFLIKWTDVFQPSDLWNNYSYMVWGAMVIGVTGNFPLGIACMVLLNLYSLL
                     ISELVAKRWSSYYRYPNCTIIAMHNVEASVFAVFADPIYNKLGLNKIKLNPKELEKKL
                     GFLGEPITLGLFLGMFIGILGNMTRINTMEAWGEIMKVGISTSAVMAIFPKVASMFAQ
                     AFAPITEAARKIMQKAGNREWYIAVNDAVGYGEPATLISGLILIPIMLVIAMVLPGNK
                     VLPVVDLLAIPYMVQGLVAIHNGNIPKVLVSGIIWFGLGLYVCTSTAPLFTDMATNIG
                     VAIPAGAMLITSFNILGKPLMGLVFFAFLSANPIYIGLSVVIYFVLWALFRKNKTSIL
                     DYLEKQALKNVEEEPVAV"
     gene            5948..7006
                     /locus_tag="KR294_003162"
     CDS             5948..7006
                     /locus_tag="KR294_003162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012101107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HBH0241218.1"
                     /translation="MGDKMRASVLYSVGDVRYEMVDIPEITDTQVLVNVKYVGICGSD
                     LPRSMVSGLSGNTKYPLILGHEFSGEVVKIGEKVKHINVGDRVAVAPLVPCGKCDYCN
                     EGNFGLCDDYNIIGTRVNGAFAEYVRVPEEHILKLPDTLDYETAAGIEPATIAYHGIS
                     KSNIRVGDSVVVLGCGPIGQFVIQWAKVFGASKIIAVDIFDEKLELSKLLGANYILNS
                     KEVNVIKEIKKITNGGADVVIETAGSRFTQEQSLFVAKKRGNIVFVGISHTELPLSAD
                     ATECILRGELTLKGSWNSYTSPYPGRAWTATLDFMGKGDIIFKPMISHKIGLNEVGDF
                     LSKMSKREINFNKILVEI"
     gene            7105..7791
                     /gene="araD"
                     /locus_tag="KR294_003163"
     CDS             7105..7791
                     /gene="araD"
                     /locus_tag="KR294_003163"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HBH0241219.1"
                     /translation="MLENLKEEVLKANLELPKKKLITYTWGNVSGIDREKGLVVIKPS
                     GVEYSNMTVEDMVVVDLEGNIVDGKLRPSSDTPTHLVLYKEFEELGGIVHTHSSWATI
                     WAQIGKSIPSCGTTHADYFYGSIPCTRKMTREEICNEYEKETGNVIIEEFMGRNPIHC
                     PGIIVNDHGPFTWGKDANEAVHNAVVLEEVAKMAYYTELMSPDNIMDKVLMNKHFSRK
                     HGKNAYYGQK"
     gene            7809..8456
                     /locus_tag="KR294_003164"
     CDS             7809..8456
                     /locus_tag="KR294_003164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HBH0241220.1"
                     /translation="MLDSLKGKIVEIAIKAEHYGLCKEKTGNFSIRDKDTGYILITPS
                     GVGREELKVEHICVLDLDGNVIEVEKGIKPSSEVLMHIEIYKTRENINAISHTHSLYA
                     TAFSVAKKPIIPIVYESVNYGGYVDIAPYERPGTLKLAKSVSKLLIDTDACLLERHGL
                     TTVGNDLDEALLKSRYVEEVAEIYYRSLVLNQFKELEVVDVDEFKSWKYPEEIKF"
     gene            complement(8629..9996)
                     /locus_tag="KR294_003165"
     CDS             complement(8629..9996)
                     /locus_tag="KR294_003165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HBH0241221.1"
                     /translation="MNLIDILNKVDAFIWGPPLLVLLVGTGILLTVKLGVVQITKLPR
                     ALKLIFSAENKGSGDVSSFAALCTALAATVGTGNIVGVATAIKAGGPGALFWMWIAAF
                     FGMATKYSEGVLAIKYRTKDKNGQVSGGPMYYIVNGMGEKWRPLAIFFAISGILVALL
                     GIGTFTQVNSITDAINNSFGIDPRITGVVLAVFVALVVFGGLKSISNVATKIVPFMAV
                     IYVVICGIILISFWNKIPETFMLIIKSAFTPTAATGGFLGATMSLAIRNGIARGVFSN
                     ESGLGSAPIAAAAAKTEWPAEQGLISMTGTFIDTIIICTLTGFSLVISGVWCSDLNGA
                     VMTQAAFNGAIPTFGPILLTVSLTLFAFTTILGWSYYGERCFEFLFGVKGMNGYRTVF
                     VAMVLLGAFLKLEVVWIIADIVNGLMAIPNLIALLALSPIIVSETKKYFEHINSPENQ
                     IKKNA"
     regulatory      complement(10186..10274)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            10702..12822
                     /locus_tag="KR294_003166"
     CDS             10702..12822
                     /locus_tag="KR294_003166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HBH0241222.1"
                     /translation="MGKILVLAEKPSVGRDIAKVLGSKNEKNGYIEGPKYVITWALGH
                     LVTLADPESYGERYKSWSLEDLPILPKHLKTVVIKKSGKQFNTVKSQMNRNDIDEIVI
                     ATDAGREGELVARWIIEKSQVKKTIKRLWISSSTDKAIKDGFAKLRSGKEYENLYYSA
                     IARAEADWIIGINATRALTTKYNAQLSCGRVQTPTLAMLLKREEEIRNFKPKEYYGLE
                     LIATKGNSDIKFIWNDKNNNSSTFSKEKIESTLKKVKGVDIKISEVNKSYKKKYSPAL
                     YDLTELQRDANKMFGFSAKETLSIMQKLYEHHKVLTYPRTDSRYLTSDIVGTLKDRIK
                     AVNISDYSKTCNKLLKSNIIANKSFVDNSKVTDHHAIIPTEQKVFMSDFSDKERKIYN
                     LVVKRFLAVLSPPFEYEQTTISATVEGEIFKAKGNKVINLGWKESYKDIEDEDEYESI
                     PNILEKDVLKVKGLKITSGKTNPPPYLNEGTLLTAMEKNGLGTVATRADIIEKLFNSF
                     LMEKKNKDIYITSKGRQLLDLVPVDLKTPELTASWEKKLLDISKGKLSKNTFINDMKD
                     YSKDIVLEVKNSDNKFKHDNLTKNRCPECGKFMLEVNGKKGKMLICEDRECNTRKTIS
                     QVTNSRCPNCHKKLELRGEGEGRIFTCSCGYREKLSSFNKRKQEEKQKASKKDVNQYL
                     KNQNKNQETFNNPFAEALAKLKNK"
     gene            12926..>13610
                     /locus_tag="KR294_003167"
     CDS             12926..>13610
                     /locus_tag="KR294_003167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FliS"
                     /protein_id="HBH0241223.1"
                     /translation="MDLSGIFKYYCKECENTWNNSSVELFENIETYSKDSQKKREKEL
                     DKLLNTISVHLERYPSDAVLRKMWVKKGEVFLQKTLEKENIFKLEKMDVEDRKKFLDI
                     TKQFIRDARKFDDDLPIGDIMQAMRNVWISNALQLLFGKEVYYSKANFAYSMLYPYTD
                     NYLDNTNIDKNDKILFNNWLEKRLLGEHIKSKDYHESKVSKMIDYIESVYPREKFTEV
                     YESLLLIFKS"
BASE COUNT         5409 a         1565 c         2403 g         4233 t
ORIGIN      
        1 ttaaaattta aacaaagaat taaattattt aagattatga ataactaata catttagtaa
       61 attactaaat atacaaaatg taaatactta tcaaaatgta taaatactta tgacatctag
      121 ttacttacag ggtttaagta gaaaaaaata tcaaagtaag tatggcatga tagttgctta
      181 tatatttatc aagaaaggag ttattaagca tggagttgag agataaactt gtaaacatca
      241 taaatacaga aaataaaaaa gatccattaa cagatgttca aatagcaaag tttttaagta
      301 caactagaga gaacataact aatttgagaa aagaacttaa tataagtaat tcaaggcaaa
      361 gaagatatcc ttatttaaaa tcagcaattt cggcaatatt acaaaagaat aagaatattt
      421 ctgtatcaga aattacaagg gaattgatga cagaaggctt taatatatct agaagagttg
      481 tggaggaact tttacctaaa gaaagtttag aaatggatgt agtagaggaa tctgaagaag
      541 aatcgaatga cccatttgaa actctgatag gtaataaagg gagtcttaga aatgctgtag
      601 agcaggctaa atctgctata ttgtatccac caaaagggtt accaacgttg attattgggg
      661 aaagtggagt tggtaagagt ttattttcta gacatatgta tgagtttgca aagcaaaaaa
      721 agatagtaaa agaaagctcc aattttgttg tatttaactg tgctgattat agtgacaatc
      781 cacaattatt attatctttg ttatttggat ataaaaaagg tgcatttaca ggtgctgaat
      841 atgatacacc aggtcttgta gaagaagctg atgaaggagt tttatttttg gatgaaatac
      901 atagattgcc tccaaaaggc caagaaatac tattttctat tttagatagg ggaaagttta
      961 ggagattagg tgaaactaat gctgaaagaa aagtaagtat tatgttgatt ggggcaacta
     1021 ctgaaaatgt agagactaat ttattattaa cattcagaag aaggatacca atgctaataa
     1081 ctttgccacc attacatgat agattactaa aagagaaaat agaccttata tacaatatct
     1141 ttcaacaaga gtgtaataga ataaatgcaa aaatatttgt agataaaaat gtgattgaaa
     1201 tacttgcact aaaaaagttt agtggaaata taggacaatt acaaaatatg attcaggttc
     1261 tttgtgcaag agcttttatg aagtttataa attccaaaga tgaagatagt gaatcgatag
     1321 tagtagtaga tataaatgaa gttttaaagc ttaaagattc ttttaaagat gctgcctttc
     1381 aagagattga atatacagag ataagaaaat atttgaaaaa tgctatattt ataccattta
     1441 atttagaaga atcatcagta aaaggaagtc ttttaagtga tgaatatata ttaccagagg
     1501 acatatacaa aacaattgaa aagaaatatt atgacctaaa atccctagac attgaagata
     1561 tagatataga gaatatttta tggactttta ttttaaatag atttgctgac ttaaagttta
     1621 atctcgatag taatgaagaa attttttcaa tgagtgattt aaatagtttt gtaagtgata
     1681 gtttagttaa actggtaaaa gaacttatga atgatatagt tgaaaaaaat atgaatttag
     1741 aagtaaataa aaatatgttc aaatatctag caatacactt agaagaagct ataaaaagaa
     1801 ttaagctaaa tcaaaagata ataaatgtaa atttagaaaa aataaagatt gacttttcaa
     1861 aagaatatga aattagtaaa agttttgcaa taaaaattga ggaatcaatt ggtattaaga
     1921 ttccagatga tgaaattgga tttataacac tctacataaa gtctgctcta aaaaatgaag
     1981 tgaaaaaaga taaagtaggg ttaataataa tttctcatgg acgtatagct acagagactg
     2041 taaatgtagt taaagaactt ttaggtgtaa agtttcctgt ggctatagat atgcctttag
     2101 atgaaaaacc aataaatata tacaataagg cagtagaact gtcaaaaata atagaccaag
     2161 ggaaaggcat attgtttttg gtggatattg gttcacttac aaacataggt caaatagtaa
     2221 ataagagaac caatataagc actaaaacta ttgatagagt agacctccta atggcactag
     2281 aagcaactag aaaagtttct atgggagagg aagaacttga tgaaatattt ttttctttgc
     2341 taaaagatag gatgggatat aactatgaat tagaaaaaca catagataaa tcaaatgcaa
     2401 ttgtaacatt atgtcttact ggagaaggaa ctgctaagta tataagtaaa acgttggaag
     2461 aaaagtatga taacactaaa tgttatcaaa tgagtgcatt ggatgaaaat ttattttgta
     2521 aaattgaaaa tctaaaagag acaaacaata tattagctat tgttgggaca ataaacccta
     2581 agataccagg tataaatttt ataccctata ataaagaact tttcaaaaat ttggatatct
     2641 atctatcaaa atcaaaacaa caagatgaca gaccagttaa atcgtatgaa agaatgcttg
     2701 atgaggattt agtgattttt gaaccagata tatattttaa aaaggattta ttagaatatg
     2761 tatgttcaat tcttataaat aaagaatatg tagaaaaaga ttacttagat tctgttttac
     2821 atagagaaga aatgcttcca acatattcta aaggagctat aggtgtgcct catggagatt
     2881 cttctactgt aaatagtaca aggtttgttt ttgttaaact aaagaatcct attgattggg
     2941 gtgtaggtaa tgtaaatttc atatttatgc cagtttttca ggctaatgat aaagagattg
     3001 ttaaaaatgt tcttgagata ctaaaagatg cagaatttat gaacaatgcc aataagtgtt
     3061 ttgataaaga tgcttttaga aggattatat ttgataaatt taaacatctg tagccatagc
     3121 aaaaaaattg agaggagtta gagtaatgaa tgtagattta atatcattgg gtttagaatc
     3181 taatgattat gaaagtgtta ttgaagaatt aggaagtata atgtgtaaaa aagaatatgt
     3241 aaaagaaaca tacataaatg ctgtcttgga aagagaaagg acattaccaa caggtctaga
     3301 tattggagaa atgtgtgttg ctattccaca tacagattca aagcatgtaa atgagtctaa
     3361 tgtagctgta gggatattga aaaatcctgt aaagtttaat tcaatgatag acccaaaaga
     3421 tagacttgat gtagaacttg tatttttatt agcagtaaag aacccagatt cacaagtaaa
     3481 actgttaaag gatttaatgt cagtttttca aaatataaag ttattaaaaa atataaaaaa
     3541 cgcatcaaca aaagaagaag tagctaaatt attggatttt atagaaattt aatgtaggag
     3601 aattttataa ataaaaaatt aaaatttaaa caatcaaagt aagtattatt tttttaatag
     3661 gtttaatctt atataaaata aaaatttaga gtgaaaaatt aggaggaaat tattatgaaa
     3721 caatttaatg tattatcagt ttgtggttca gggacagtta catcatctat ggtagcaggt
     3781 aaattaaaag aagtactagg taataagggg atttctatta ctacaacaga agctagacca
     3841 acagaagcac taaatttagc acaatcagga agatttgact ttataacatt tacgagtcca
     3901 cttcaaacag gcgattatgg aataccaact ataaatgcat ttgcttgcct aactggtata
     3961 ggggaagagg cattctttga agaagttttg actgttattg aagggataga taagtaagtt
     4021 ttggagacgt gaatttatag tatttaaatc aatgatttag atactataat aagctaatat
     4081 taactaaata tttgtggaaa aaacatttta tatgttgtca taaattaaaa aattataaaa
     4141 atagtcactt aagtattaaa ttaagcttat aaatatttat aagtaggagg gaaaaagatg
     4201 ttagaattta tgaaatctat aatcgataca tttggttctg caattatagt tccaattata
     4261 atattcataa tagcaaagat atttaaagta actactaaga aatcgtttct ttctgctgtg
     4321 tatgcaggag ttgctttaca aggttttaca ctgattttaa attcatttac accaataata
     4381 acaccagtta tcaataggat ggttgagagt acaggagtaa acctaccagt ttttgatgtt
     4441 ggttggcaag caacatcatt ggttgcattt tcaacaagtg caggtatgat atatttaggt
     4501 cttggtatat tattacaaac aattttattt ttgataaaat ggacagacgt gtttcaacca
     4561 tcagatttat ggaataacta ttcttatatg gtatggggag caatggttat aggagtaaca
     4621 ggaaattttc ctttaggtat agcatgtatg gttttattaa acctatatag tttattaata
     4681 tcagagttag ttgcaaagag atggtctagt tactatagat atcctaattg tacaataata
     4741 gctatgcata atgttgaagc ttctgtgttt gcagtatttg cagaccctat atacaataaa
     4801 ttgggattaa ataaaataaa attaaatcca aaagaattag agaagaaatt agggttttta
     4861 ggtgaaccaa ttactttagg tcttttttta ggtatgttta taggtatatt aggtaatatg
     4921 acgagaataa atactatgga agcttgggga gaaataatga aagtaggtat atctacaagt
     4981 gcagtgatgg caattttccc taaagtagca agtatgtttg ctcaagcatt tgcacctata
     5041 acagaagcag ctagaaagat tatgcaaaaa gctggaaacc gtgagtggta catagcagta
     5101 aatgatgctg ttgggtatgg tgaacctgca actttaatat caggtcttat attaattcca
     5161 ataatgcttg taatagctat ggtacttcct ggtaataagg tattaccagt tgtggattta
     5221 ttggcaattc catatatggt tcaaggttta gttgccatac ataatggtaa tataccaaaa
     5281 gtattggttt caggtataat ttggtttgga ttaggattat atgtttgtac atctacagca
     5341 ccattattta cagatatggc tacaaatata ggtgtagcta tacctgcagg agcaatgtta
     5401 ataacaagct ttaatatact aggaaaacct ttgatgggat tagttttctt tgcatttcta
     5461 agtgcaaatc caatttatat aggtctttca gttgtaattt actttgttct atgggcattg
     5521 tttagaaaga acaaaacaag tattcttgat tatttagaaa aacaagcact taaaaatgta
     5581 gaagaagagc ctgtagcagt ttaagtttat aaaaatgaaa taagaataat taaaggagtt
     5641 tataattgat tttatataag tatcagataa tacctgagaa atatttaaat gaaatataga
     5701 cttcttttta tttgataata tttgtaatta taatgcattg tatctttata gttgagtttt
     5761 ctgtataacc tgctatttaa aacatactct tttatattta tacagtaatg tggtttaatt
     5821 ttataaaatg taatctctac tggtaaaaga ctttgtatat aaggcatttg cctgaataaa
     5881 ccatttatct tttgtatggc atagatattg ctatatagaa gtatatagca tgaaaggaga
     5941 tatttatatg ggagataaaa tgagagcatc agtattgtat agtgtaggtg atgtcagata
     6001 tgaaatggta gatataccag aaataacaga tacgcaagtg cttgtaaatg taaaatatgt
     6061 tgggatatgt ggttcagatt tacctaggtc tatggtaagt ggtttgagtg gaaatacaaa
     6121 atatccattg attttaggac atgaattttc tggcgaagtt gttaaaattg gagaaaaagt
     6181 aaagcatatt aatgtaggag atagagtagc tgttgcacca ttagtacctt gtggaaaatg
     6241 tgattattgt aatgaaggta attttggctt gtgtgatgat tacaatataa ttggaacaag
     6301 agtaaatgga gcgtttgcag aatatgtaag agttccagaa gaacatattt taaaactacc
     6361 agatacattg gattatgaaa ctgctgccgg aattgaacca gcaactatag cttatcatgg
     6421 gatttcaaag tctaatatta gagtaggaga tagtgtagtt gtgttaggat gtggtccaat
     6481 aggtcagttt gttatacaat gggcaaaggt gtttggtgca tctaagatta tagcagttga
     6541 tatttttgat gaaaaattag aactttctaa acttctagga gcaaactata tacttaactc
     6601 aaaagaagta aatgtaatca aagaaataaa aaaaataaca aatggtggtg ctgatgttgt
     6661 aatagagact gctggtagcc gatttacaca agaacaatct ctatttgtag caaaaaagag
     6721 gggaaatata gtgtttgtag gtatatcaca cacagaatta ccacttagtg cagacgctac
     6781 tgagtgtata ttacgtggag aacttacctt gaaaggttct tggaattcat atacaagccc
     6841 ttatcctgga agagcatgga ctgcaacatt ggattttatg ggaaaaggtg acattatttt
     6901 taaacccatg atttcacata aaataggtct taatgaagtg ggtgactttt taagtaaaat
     6961 gagcaagaga gaaattaatt tcaataaaat cctagtagaa atataaaaat ttaataaaaa
     7021 attctaaaag caattaaatt ttataactat gacattaaat aaaataaaaa taattttctt
     7081 aaataaaata taggaggaag aaaagtgtta gaaaatttaa aagaagaagt attaaaagca
     7141 aacttagaat tacctaagaa aaagctaatt acttatactt ggggaaatgt aagtggaata
     7201 gatagagaaa aaggattagt ggtgataaag ccaagtggtg tagagtatag taatatgact
     7261 gtagaagata tggttgtagt tgatttagag ggaaatatag ttgatggcaa attaagacct
     7321 tcttcagata ccccgactca tctagtttta tataaagagt ttgaagaatt ggggggaata
     7381 gtacatacac attcaagttg ggcaacaatt tgggctcaaa taggaaaatc tataccatct
     7441 tgtggtacta ctcatgcaga ttatttttat ggaagtatac catgtaccag aaaaatgact
     7501 agagaagaaa tttgcaatga atacgaaaag gaaactggaa atgtaatcat tgaagaattt
     7561 atgggaagaa atccaattca ttgtccagga ataattgtaa atgaccacgg accttttaca
     7621 tggggaaaag atgcaaatga ggctgtacac aatgcagtag ttttagaaga agtcgcaaag
     7681 atggcttatt atacagagtt aatgagtcct gataatatta tggataaggt tcttatgaat
     7741 aagcattttt caagaaaaca tggaaaaaat gcatactatg gtcaaaaatg attatctgga
     7801 ggtgaattat gctagactct ttaaaaggta aaattgtgga aatagcaatt aaagcagagc
     7861 attatggttt atgtaaagaa aagactggta attttagtat tagagataag gatactggat
     7921 atatacttat aaccccatca ggtgtaggaa gagaagaatt aaaagttgaa catatttgtg
     7981 tattggattt ggatggaaat gtaatagaag ttgagaaagg tattaagcca agtagtgagg
     8041 tattgatgca tattgaaata tacaaaacaa gagaaaatat aaatgccata tcacatactc
     8101 attctttata tgcaacagca ttttcagtag caaagaaacc aattatacca attgtatatg
     8161 aatcagttaa ttatggcggt tatgtagata ttgctccata tgaaagacca ggaactttaa
     8221 aattagctaa gagtgtttca aaattactga tagatacaga tgcatgctta ttagaaagac
     8281 atgggttgac aactgtaggt aatgatttag acgaagcatt attaaaatca agatatgtgg
     8341 aagaggtagc agaaatatac tataggtctt tagtattaaa tcaatttaaa gaacttgaag
     8401 tagtagatgt tgatgagttt aaatcttgga aatacccaga agaaataaag ttttaatcta
     8461 aataattttc attgaagtgg ttaattaaaa tatatgtatt atttatatca attactatgt
     8521 tttattatgt taattaccgt attttgcaaa tatatttatt acattttttc aaaaaaatat
     8581 agaatccgaa agccatataa aattgacttg ggattctata ctttttattt atgcattttt
     8641 ctttatctga ttttctggag aatttatatg ttcaaaatat tttttagttt cagatactat
     8701 tataggtgat aatgcaagta aagctataag gttaggtatt gccataagcc catttacaat
     8761 atcagcaatt atccaaacaa cttctaactt taagaaagca cctaataaca ccatagccac
     8821 aaatacagtt ctatacccat tcatgccttt tacaccaaac agaaattcaa aacatctttc
     8881 tccataataa ctccatccca aaattgtagt aaatgcaaat aatgttaaac taactgtaag
     8941 taatattggt ccaaatgtag gaattgctcc gttaaaagct gcttgtgtca taacagctcc
     9001 atttaggtct gaacaccaca ctcctgaaat aacaagagag aatccagtaa gagtacagat
     9061 tataatagta tctataaaag tacctgtcat agatataaga ccttgttccg ctggccattc
     9121 agttttagca gcagcagcag ctattggagc actacctaga ccagactcat ttgaaaatac
     9181 accacgagcg ataccatttc taattgccag tgacatagtt gctcctaaaa aaccaccagt
     9241 agcagcagta ggtgtaaatg cacttttaat tattaacata aaagtttcag ggattttatt
     9301 ccaaaaagat attaaaatga ttccacagat tacaacatat ataactgcca taaaaggtac
     9361 tattttagta gctacattag atatactttt aagtcctcca aatacaacca aagctacaaa
     9421 tactgctaat acaacccctg taattctagg gtctatcccg aaactattat ttattgcatc
     9481 tgttattgaa tttacttgag taaaagtacc gattcctaaa agtgcaacta gtataccact
     9541 tatagcgaaa aatattgcaa gaggtctcca tttttctccc ataccattta ctatgtaata
     9601 cattggccca ccagacactt ggccattttt atctttagtt ctgtatttta ttgcaagaac
     9661 accttctgaa tacttagtag ccattccaaa gaatgctgct atccacatcc aaaaaagtgc
     9721 accaggtcca ccagctttga tagctgtagc aacaccaaca atattaccag taccaactgt
     9781 agcagctaga gcagtacata aggctgcaaa acttgaaaca tcaccactac ctttgttttc
     9841 agcagagaat attaacttaa gagctcttgg cagtttagtt atttgaacaa ctccaagctt
     9901 aacagtaagt agtataccag taccaactaa tagtaccagt aggggtggtc cccaaataaa
     9961 agcatcaact ttgtttaaaa tatcaattag attcataaaa acactccctc attttttttg
    10021 ctttacataa tcaatagaat ttttaatgaa gtaattgaca ggaaataagt ataatttatt
    10081 aataatttct agtgtaataa aaaaagctaa atctaaaaaa gattcagctc tggatgtaca
    10141 ctaattagca accaaaataa aagtattagt aaatactgtt tttggtagat aatccctgtc
    10201 cttttgcctg agagattgag cataaaagcc ttgccccttc ggcgcccata atgggtctct
    10261 ccagagttcc gtaaatttta cagtcctact tttaaaagta cctgagagtg ttactccttc
    10321 ggtgtgctat atagcaactc ttctataaaa tcttaaccgg atattgattt gtcatagctt
    10381 attgtattaa taatattaat ataagttttt atgttttgtc aactaaaaaa ttaaaaaaca
    10441 aagaaaaaat ataaaaatgt aagcctattt acgaattata aacttagaaa gatgagtaat
    10501 atacgtgaaa atgaattttg taatacacat acaaatgaag tgtaaaataa gttctaaata
    10561 aaaaaataat aaaatcttaa ataattaatt agatatgatt aaattatggt aatattatag
    10621 ttacgatatt aagaaaagtt ctatttagtt agattttaag cgtaatatga gattatgtat
    10681 agagaaagga tgtattttta gatgggaaaa atattagtgc tagcagaaaa accttctgtt
    10741 ggaagagata tagcaaaagt tttagggtca aaaaatgaaa aaaatggtta tatagagggg
    10801 ccaaagtatg tgataacttg ggcactaggt catttggtta cacttgctga ccccgaaagt
    10861 tatggagaaa gatataaatc atggagctta gaagacctgc caatacttcc caagcacctt
    10921 aagactgttg taataaaaaa gagtggaaag cagtttaata cagttaaatc gcaaatgaat
    10981 agaaatgata tagatgaaat agttatagca acagatgcag gtcgtgaagg agaacttgta
    11041 gcaaggtgga taatagaaaa atcacaggta aaaaaaacta taaaacgtct ttggatttct
    11101 tcaagtacag acaaagcaat aaaagacgga tttgcaaaat taagaagtgg aaaagaatat
    11161 gaaaatttgt attactcagc aatagcacga gcagaagctg attggattat tggaataaat
    11221 gcaaccagag ctttgacaac aaagtacaat gcacagcttt cttgtggaag agtacaaact
    11281 cctactcttg caatgttgct taaaagagaa gaagaaataa gaaatttcaa acctaaagag
    11341 tattatggat tagaattaat tgctacaaag ggaaattcag atataaaatt tatttggaat
    11401 gataaaaaca ataattcttc aacttttagt aaagaaaaga tagaatccac attaaaaaaa
    11461 gtaaaaggtg tagacataaa aatatctgaa gtaaacaagt catataagaa aaaatattca
    11521 cctgcactct atgatttaac agaattacaa agagatgcaa ataaaatgtt tggattttca
    11581 gcaaaagaaa ctttatctat aatgcaaaaa ctgtatgaac atcataaagt acttacttat
    11641 cctagaactg attctagata tttaacatca gatattgttg gaacattaaa agatagaata
    11701 aaagctgtaa atattagtga ttattcaaag acttgtaata aattattaaa aagcaatatt
    11761 atagctaata aatcgtttgt tgacaattca aaggtaacag accatcatgc aataatacca
    11821 acagaacaga aggtattcat gagtgatttt agtgacaaag agcgaaaaat atataatctt
    11881 gtagtaaaaa gatttttagc agtactatct cctccttttg aatatgagca gacaactata
    11941 agtgcaactg tagaaggaga aatatttaag gctaagggaa acaaagtaat aaatttaggt
    12001 tggaaagaaa gttataaaga tattgaagat gaagatgagt atgaaagtat accaaatatt
    12061 ttagaaaaag atgtacttaa ggtcaaggga ttaaagataa cttcaggaaa aacaaatcca
    12121 ccaccatact taaatgaggg aacattattg actgctatgg aaaagaatgg tctagggaca
    12181 gttgctacaa gagcagatat aatagaaaaa ttattcaatt catttttaat ggaaaagaaa
    12241 aataaagata tatatataac atcaaaagga agacaattat tagatttagt tccagtagac
    12301 ttaaagacac cagaacttac agcttcatgg gaaaagaaat tattggatat ttcaaaggga
    12361 aaacttagta aaaatacatt cataaatgac atgaaagatt attcaaaaga tattgtacta
    12421 gaagtaaaaa atagtgataa taaatttaaa catgataact taactaaaaa tagatgtcca
    12481 gaatgtggta aatttatgtt agaggtaaat ggtaaaaaag gtaagatgtt gatttgtgaa
    12541 gatagagagt gtaatactag aaaaactata tcacaagtaa ccaattcaag atgtcctaac
    12601 tgccataaaa aattagaact tcgtggagaa ggtgagggga gaatcttcac ttgtagttgc
    12661 ggatacagag aaaagttgtc gtctttcaac aagagaaagc aagaagaaaa acagaaggca
    12721 tcaaaaaaag atgttaatca atatttaaaa aatcaaaata aaaatcaaga gacatttaat
    12781 aatccatttg cagaagcatt agctaagcta aaaaacaaat aattttaaag ttattattat
    12841 acacaattat aactttaact gtatattagt tatatgtact gatataatat agtgtatagt
    12901 ttaggcatga aagtagggct gttaaatgga tttaagtggc atatttaaat actattgtaa
    12961 agagtgtgaa aatacatgga ataattcgag tgttgaatta tttgagaata tagaaacgta
    13021 tagtaaagat tcacaaaaaa agagggaaaa agaattagat aaattgctaa atacaatatc
    13081 agttcattta gagaggtatc caagtgatgc tgtattgaga aaaatgtggg taaaaaaggg
    13141 cgaggttttc ttacaaaaga cattggaaaa agaaaatatt tttaagttag aaaaaatgga
    13201 tgtagaggat agaaaaaaat ttttagatat aacaaaacag tttattagag atgctagaaa
    13261 atttgatgat gatttaccta taggtgatat tatgcaagct atgaggaatg tatggatttc
    13321 aaatgcatta caattattat ttggtaaaga agtatattat tcaaaagcta actttgcata
    13381 tagtatgtta tatccatata ctgataatta tttagacaat acaaatatag ataaaaatga
    13441 taagatttta tttaataact ggttagaaaa aaggctcctg ggagaacaca ttaaatctaa
    13501 ggattatcat gaaagtaaag tatctaaaat gatagattat attgaaagtg tataccctag
    13561 agaaaagttt acagaagttt atgaatcgtt attattaata tttaaaagtc
//
LOCUS       DAEPKC010000109        12966 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.109, whole genome shotgun sequence.
ACCESSION   DAEPKC010000109 DAEPKC010000000
VERSION     DAEPKC010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12966)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12966)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12966
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.109"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            47..748
                     /locus_tag="KR294_003168"
     CDS             47..748
                     /locus_tag="KR294_003168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4253 domain-containing protein"
                     /protein_id="HBH0241224.1"
                     /translation="MSIEDLYDFECVPLNNEIDIDVLFEKMIEDGKEKEYTPIIVIDE
                     KVGLLRKNIDMITKEYGSLENYREYCLTKYNEIDVNQFFDFRKSEISELLKELIDLED
                     DFYDYKHFRPIMNIDIFHEYNKVYIAKIPTIKPYEVFAYIPIGGFNDCPRDEEHIAIA
                     KYWYEKHGIFPIAIGCDTVQYSVKNLTKDGKKFDDLCIELVFYCEDIIIQGYETLKAL
                     KDVLKRSTIVLFWWD"
     gene            1018..1836
                     /gene="larE"
                     /locus_tag="KR294_003169"
     CDS             1018..1836
                     /gene="larE"
                     /locus_tag="KR294_003169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent sacrificial sulfur transferase
                     LarE"
                     /protein_id="HBH0241225.1"
                     /translation="MEVNFVKEKEKLDKLKKMLLELGSVVVAYSGGVDSNFLLKVAKD
                     TLGENVIAVTIHAMMHSSREIEEAKQYTQNFGVKHIILNIENFDLKEFKENGVDRCYH
                     CKKYIFSKIKEVAKEHNIKYIVDGTNIDDLGDYRPGLKALSELGVISPLKDSSLKKEE
                     IRSLSKTLGLNTFNKPSFACLASRIPYGVEITDENLRIVEKSEEYLSNLGFSQFRVRM
                     HGDIARIEVGQEELGKFFENNNFNKVDTKLKIFGFKYVTLDMSGYKMGSMNLNV"
     gene            1891..3039
                     /locus_tag="KR294_003170"
     CDS             1891..3039
                     /locus_tag="KR294_003170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HBH0241226.1"
                     /translation="MKNYTLISPCFFGMEKMLAREITNLGYEIIKTEDGRITYKTDEF
                     GIAKSNMWLRCAERVHLKIAEFEAKSFDELFENTKRINWSRYIPYGAQFPISKASSIK
                     SKLYSTPDVQAIVKKAIVESLKKSYLEDGLLKEDKEKYPIFVFIHKDKVTISIDTTGD
                     ALHKRGYREKANKAPIRETLAAGLIYLTPWKAGRVLVDPMCGSGTILIEAAMIGINMA
                     PGLNREFISEKWRTLDKKIWWDVRKDAFNKIDNESKFKIYGYDIDEESIDIARENAEI
                     AGVDEYIEFNVGDATQFKSEDEFGFIITNPPYGERLEDKDSVKQLYKELGYAFRKLKN
                     WSYYLITSYEDFEYEFGQKADKKRKLYNGMLKTNFFQYPGPKPPRNNK"
     gene            3175..4563
                     /locus_tag="KR294_003171"
     CDS             3175..4563
                     /locus_tag="KR294_003171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBH0241227.1"
                     /translation="MKVLKLITVVALMMLFVTGCNIKTESPEQLAKIPDYDDTKKVLY
                     DGIDQLLKPDSSMILPSNTKEVGKINKVDLNSDGIDELVVFEQKEDLSNNVSQVGFVT
                     LSYNGEKYVLGDHFLENGESIEYANFYDLDSDGYKEVILLVKSKDKTNMHIYKVVDNE
                     ITKIYDLDASWLQNKEDFNDMKVKIGYIDGDDKLDILMLHLNNKTNEMFASVANFDGK
                     MKIKDSVKFENVKNLSELYITLGNVASSVGNSSAAIKGIVLDIPILKDNNYITQILYM
                     KDGKINKAFSDYDKTITKSYYIPVDDIDKDKIIEIPIVAGSTGNNKNTYSSKSSATIS
                     WYRWNGKEGADSSLIFTSQIYYNYKYNFKLFIPNNLFDKILVEQEFVGEKAVFKFYYF
                     DYSDRKNLFNIVVESKNKLEDRKNTGTQNSIVLQESDEYTFLLVVNNANEMDKLDMTI
                     DALKEYFSLIYG"
     gene            4592..5290
                     /locus_tag="KR294_003172"
     CDS             4592..5290
                     /locus_tag="KR294_003172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0241228.1"
                     /translation="MKEKILILEDEIGIRSFVSINLKREGYEIVEAGTGREAIEKMTT
                     EKDITIALLDVMLPDISGIEVCKFIRENFDQVGIIMLTAKAQEDDKIEGFISGADDYI
                     IKPFSIKELLVRVSALLRRVAKDDSSVKSSEIVSPPFILDIDKRKLFKNGKEIELTPT
                     EFSIVKYLISNAKQSLSRDQILDEVWGTNYLYDFKIVDVNIRRIRNKIEDDPSKPKYI
                     QTIWGYGYCFRKEE"
     gene            5293..6726
                     /locus_tag="KR294_003173"
     CDS             5293..6726
                     /locus_tag="KR294_003173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH0241229.1"
                     /translation="MLHFEGLRKKVIKNYFIIIIIMVTLFEGLFMFYIQNYYYDSVKQ
                     LLESEIKYADEYNAITMETTSFEKKVKNIFDKQPLTKNSEFGISIIDKDKNIILDQYG
                     FKSKEKANYEDVNNALKDIKTKNLTPYTYRIPDTGEHVMSISLPLKVNNIIEGVVRYT
                     VSLDAIDNAILKQATWLILAGIFILIIAILISLKFAETLIKPLRELKKFANELAVGNY
                     NIKLEKMKIVDDEIGDLAQTFEHMAHEIDKSEKLKEEFISSVSHELRTPLTSIKGWSE
                     TLGYESITREELDLGLGIIQDETERLIKLVEELLDFSRLSSDRIKLHVDIVDVEGLIV
                     GVVNQLKVKAAEKDISLLFEFENEFIENIQGDKNRLRQVLINLIQNSFKFTSQGGYIK
                     VVASQDEEITTISVEDNGSGIEKQNLNKVLDKFFQEDYNKAGSGLGLAISNEIVKLHG
                     GRMKIESEKNVGTKITFNIKNKFAKQA"
     gene            6748..7485
                     /gene="truA"
                     /locus_tag="KR294_003174"
     CDS             6748..7485
                     /gene="truA"
                     /locus_tag="KR294_003174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011010156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HBH0241230.1"
                     /translation="MRNIKMIVAYDGSRYKGYQKLGDNNMTIQEKLENVLSKMTNETV
                     EIIGSGRTDMGAHARGQVVNFRTNCMDSLDKIQKYLYEYLPEDIVVKTVEEVDERFHS
                     RYNVKSKTYMYKIDNNKYHNPFIRKYATHVSKKLDLDRMRKASEYLVGEHDFTSFASS
                     KSKKKSNVREIYSINIKEDDNVIEIYVEGNGFLYNMVRIIVGALIDVGLKRRAPQDIK
                     YMLESKDRCQSSDTAPAKGLCLWKVTY"
     misc_binding    7596..7803
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            8056..9255
                     /locus_tag="KR294_003175"
     CDS             8056..9255
                     /locus_tag="KR294_003175"
                     /EC_number="6.3.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HBH0241231.1"
                     /translation="MKEKVVLAYSGGLDTSIIIPWLKENYEDIDVIAVCGNVGQEDKM
                     EDVYEKALQSGASKAYVDDISEEFVTETIFKAVKAEAKYEGKYLLGTSLARPIIAKKL
                     VEVAHKEGAKYICHGCTGKGNDQVRFEATIAALDPTIKVIAPWRIWDIKSREDAIDYA
                     EKHNIKVTATKAKIYSVDANLWHVSTEGGDIEHLENEHKKDVYKQCVDPEDACDVAEY
                     VEVYFEKGVPKKVNGEELSPVALIHKLNELGCKHGIGVIDIVENRLVGMKSRGIYETP
                     GGTILYEAHNILESATLDKDTLHFKQMVSYKYGELIYNGLWYCKLRESIDAFMEQTQD
                     NVTGTVKVKLYKGNIKPAGIFTENALYDEGISSFGNSELYDHKDAEGFINLFTLPLKI
                     RAMKAGK"
     gene            9502..10548
                     /locus_tag="KR294_003176"
     CDS             9502..10548
                     /locus_tag="KR294_003176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4872 domain-containing protein"
                     /protein_id="HBH0241232.1"
                     /translation="MRKIIEIKHHSHDYECMWNGIEDLYINKTGEYLPNDFFFLLSGF
                     GSFCYMKTNKADLKRMVALGDGRTKQMYKFLAPIVGFEYKHHEFKKYEQALKKAKSEI
                     DDGYPVILGALDMYYLPYYKKLYHKEHIPFHYILMVGYDDEGIYLYDCGRTELLHLSY
                     DKLRESMNCNSPGLSKENTICTIRMNTSKNKYNIAREAIAIKRDMFLNPPKGFLGYKG
                     FEKFIKELPQWNTELDKDDYDKILTNMVMFFGTVPTIPNAIKGIKEPDTVQFKGGFDK
                     MSRMLNSIGEEYKNNSFIQVADIFDKTAIIIEKISNIIIDYLTQTCDDTEQLPLLFSE
                     VLEHMKTGYLILDV"
     gene            10656..11819
                     /locus_tag="KR294_003177"
     CDS             10656..11819
                     /locus_tag="KR294_003177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH0241233.1"
                     /translation="MRTVKQVSDLTGISVRALHYYDEIGLLKPNKITDAGYRLYDDES
                     IKTLQQILFFKEIDIPLREVKEIMSSQYFDKVEALKNQKKLLILKRKRLDELIELINQ
                     TLRGEGNIDFKEFDMSEYFNVLEEFKREHRNKVIKIYGSVEKYNEYIERVKSNEEKIA
                     KMAIKQYGTIEKFAKAIKTNFSSDILNLGEKFDRYKNDCLKEKHPKLKELYRKLVEDL
                     SRNPSSTDLQEIAKAITDISKKDYEIFSMDTGDDNWYYMVQNYLVNPMWIEEVDKKYG
                     SGAGKFIGQVLKTYLRDRKPKINTLYEKLVEDLSRDCSSREVQSIVEEIDNEMKRSNE
                     FYKIDNGERYFDYMSELYLQDSNYIKVTDKNYGDGASKFIGEAFKIYFDNNNC"
     gene            complement(11908..12288)
                     /locus_tag="KR294_003178"
     CDS             complement(11908..12288)
                     /locus_tag="KR294_003178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4363 family protein"
                     /protein_id="HBH0241234.1"
                     /translation="MKSTTFVILWTILFVLFGFYVNNKLYDFTEGYKDNISVLEKSIE
                     NEDWEKAQKEADSISTSWNKEKNHWYKVLNHEYFDEIGLRFNILDKAIYTENKLKSLE
                     EVESIKTYLGNIIESVKFDVNYIF"
     gene            complement(12291..12950)
                     /locus_tag="KR294_003179"
     CDS             complement(12291..12950)
                     /locus_tag="KR294_003179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HBH0241235.1"
                     /translation="MTVVLIRSIILYITVLIALRVMGKGEIAEMNCFDLVITLLIAEV
                     ASVPMENNNIPIINGVAAISGLVIMQTLISFLSLKSRKLSSFLSGKPSVLIDKGKIVY
                     KELKKERISIDELLEQLRIQGYFNLKDVQYAILETDGNLSVVPASSYNSTPPRAFNHL
                     PIPLILDGRIINKNLDIAQKDTNWLMGILKSNHIETFKDVLICVLDENDKIFIQNKKG
                     D"
BASE COUNT         5213 a         1289 c         2257 g         4207 t
ORIGIN      
        1 aataaaactt tcaaaaaatt aaatctaaaa agaataggag ataaatatga gtattgaaga
       61 tttatatgat tttgaatgtg ttcctttgaa caatgagatt gatattgatg ttttatttga
      121 aaagatgata gaagatggaa aagaaaaaga atatacacca attatagtca ttgatgaaaa
      181 agtagggcta ttaagaaaaa atatagatat gattactaaa gagtatggtt ctcttgaaaa
      241 ctatagagag tattgtttaa caaaatataa tgaaattgat gtaaatcaat tttttgattt
      301 taggaagagt gagatttcag aattattaaa ggagctaatt gatttagaag atgattttta
      361 tgattataaa cattttagac ccattatgaa tatagatata tttcatgaat ataacaaagt
      421 ttacatagct aaaattccaa caattaaacc atatgaagta tttgcataca tacctattgg
      481 cggatttaat gattgtccta gagatgaaga acatatagct attgcaaaat attggtatga
      541 aaagcatgga atctttccaa tcgcaattgg atgtgataca gttcaatatt ctgtaaaaaa
      601 tttaactaaa gatggtaaaa aatttgatga cttatgtatt gaattagtat tttattgtga
      661 ggatattatt atacaagggt atgaaacctt aaaggctctt aaggatgtat taaaacgctc
      721 tacaatagtg cttttttggt gggattgata ttctatcatt tagatagtat taaattgtta
      781 gtcaccaaga atccacttgc tttagttata gggagtgtgt caaactaggt ttttatacac
      841 agtgtagcat agtaatatgt ttaaattaca aaggttaaaa aaatacttta atatttttaa
      901 tattataatt aatagattta aggtaattat aatttataaa ataaatactt tatatgttat
      961 aatcattaag aatgtaaaaa aataatatat agttttatag ttcatatttt tccagatatg
     1021 gaggtaaatt ttgtgaagga aaaagaaaaa ttagataaat taaaaaaaat gttacttgaa
     1081 ttaggcagtg ttgtagttgc ttattctggt ggagtagata gtaatttttt gcttaaggtc
     1141 gcaaaagata cattaggtga aaatgttata gctgtgacta ttcatgcaat gatgcattca
     1201 agtagggaaa ttgaagaggc taaacaatat actcaaaatt ttggtgttaa acatatcata
     1261 ttaaatatag aaaactttga tttaaaagaa tttaaagaaa atggtgttga tagatgttat
     1321 cattgtaaaa aatatatatt ctctaaaata aaagaggtag caaaagaaca taatataaag
     1381 tacatagtag atggaacaaa tatagatgat ttaggagact atagacctgg gcttaaggca
     1441 ttgagtgaat taggagtaat tagtccatta aaagatagta gtttaaaaaa agaagaaatt
     1501 aggtcgcttt caaaaacatt aggattaaat acttttaata aaccatcatt tgcatgtctt
     1561 gcgagtagga taccttatgg agttgaaata acagatgaaa atttaagaat agtagaaaag
     1621 agtgaagaat atctatccaa tttaggtttt tctcaattta gagtgagaat gcatggagat
     1681 atagctagaa tagaagttgg acaggaagag ctaggtaaat tttttgaaaa taacaatttt
     1741 aataaagttg atactaaatt aaaaatattt ggctttaaat atgttacact agatatgtca
     1801 ggatataaaa tgggaagcat gaatttaaat gtgtagatta ttttaaaaat aaataagttt
     1861 tatagttaat ataaggaaac aggaggtttt atgaaaaatt atacgttaat atcgccatgt
     1921 ttttttggaa tggaaaaaat gctggctaga gagattacta atttaggata tgaaataata
     1981 aaaacagaag atggaagaat aacatataaa actgatgagt ttggaatagc aaagtcaaac
     2041 atgtggttga gatgtgctga aagagtacat cttaaaattg ctgaatttga ggcaaaaagc
     2101 tttgatgaat tatttgaaaa tacaaaaaga ataaactggt ctagatatat accttatgga
     2161 gctcaatttc ctatatcaaa agcttcctct ataaaatcaa aattatacag tacaccagat
     2221 gtacaagcca tagtaaaaaa ggctatagta gaaagcttaa agaaaagtta tttggaggat
     2281 ggtttgctta aagaagataa ggagaaatac cctatttttg tatttataca caaagataaa
     2341 gtaaccattt ctatagatac aacaggagat gctttgcata agagaggata tagagaaaag
     2401 gcaaataaag ctccaataag agagacttta gctgctgggc ttatttattt aactccctgg
     2461 aaagcaggta gagttttagt agaccctatg tgtggttctg gtactatatt gattgaagct
     2521 gctatgattg gtataaatat ggcacctggc ttaaatagag agtttatatc agaaaagtgg
     2581 agaactcttg ataagaaaat atggtgggat gtaagaaaag atgcttttaa taagatagat
     2641 aatgaatcta aatttaagat ttatggatat gatatagatg aagaatctat agatatagct
     2701 agagaaaatg ctgaaatagc aggtgtagat gaatatatag agtttaatgt aggagatgca
     2761 actcaattta aaagtgaaga tgagtttgga tttataatca ctaatcctcc ttacggagaa
     2821 agattagaag ataaagacag tgttaaacag ttgtataagg agcttggtta tgcatttaga
     2881 aaattaaaaa attggtcgta ttatttgata acttcttatg aagactttga atatgagttt
     2941 gggcaaaaag cagataaaaa aagaaaattg tataatggta tgttaaaaac taactttttc
     3001 caatatccgg gtcctaagcc tcctagaaat aataaataag ttttacatga tttatttgta
     3061 aaatataaaa ttttattaaa ataagtaaaa cattatgatg ccctgaaacg tctaattatt
     3121 gtgaggagat ttttgtgaac aaatttaaag atttatagga ttaggaggag ttaaatgaaa
     3181 gtgttaaagc ttattactgt agtagccctg atgatgttat ttgttactgg atgtaatata
     3241 aaaactgaat ctccagaaca attagcgaag atacctgact atgatgatac aaaaaaagta
     3301 ttgtatgatg gtattgacca gttactaaaa ccagattcat ctatgatatt gccttctaat
     3361 acaaaagaag taggaaaaat aaataaggta gatttaaaca gcgatggaat tgatgaatta
     3421 gtagtatttg aacaaaaaga agatttaagt aataatgtga gtcaggtagg gtttgtaacc
     3481 ttgagttaca atggagaaaa atacgtactt ggagaccatt ttttagaaaa tggcgaatca
     3541 atagaatatg ctaattttta tgatttggac tcagatggat ataaggaagt tatcttattg
     3601 gttaaatcca aagacaaaac gaatatgcat atatataaag tagtagataa tgaaataaca
     3661 aaaatatatg acttggatgc atcatggctt caaaataaag aagattttaa tgacatgaaa
     3721 gtaaaaattg gatatataga tggagatgac aagttagaca tattgatgct tcatttgaat
     3781 aataagacta atgaaatgtt tgcaagtgtt gcaaattttg atgggaaaat gaaaatcaaa
     3841 gattctgtta agtttgaaaa tgtaaaaaac ttaagtgaat tatatataac attaggtaat
     3901 gttgcttcat ctgttggaaa ttcttctgca gctataaaag gtattgtact tgatattcct
     3961 atattgaaag ataataacta tattacgcag atactttata tgaaagatgg gaaaattaac
     4021 aaagctttta gtgattatga taaaactatt actaaatctt attatatacc tgtagatgat
     4081 attgacaaag ataagattat agaaatacct atagttgcag gcagtacagg taataataaa
     4141 aatacttata gttctaaatc atctgcaact ataagttggt atagatggaa tggaaaagaa
     4201 ggtgctgact caagtttaat atttacaagt cagatatatt ataattataa atataatttt
     4261 aaattattta ttccaaataa tttatttgat aaaatacttg ttgaacagga atttgttgga
     4321 gaaaaagcag tatttaaatt ttactatttt gactattcag accgtaagaa tttatttaat
     4381 atagtagtag agagtaaaaa taaacttgaa gatagaaaaa atacaggtac tcaaaattct
     4441 attgtacttc aagagagcga tgaatatact ttcttactag ttgtaaacaa tgcaaatgaa
     4501 atggataagc tagatatgac tatagacgca ttaaaagaat atttctcatt aatatatggt
     4561 taatattata ctcaattgga ggttttattt tatgaaggaa aagatactta tactagaaga
     4621 tgaaattggt attagaagtt ttgttagtat aaacttaaaa agggaaggct atgaaatagt
     4681 tgaggcaggt actggaagag aagctataga aaaaatgaca acagaaaagg atattacaat
     4741 agctctttta gatgtaatgc ttccagatat aagtggtata gaagtatgta aatttataag
     4801 ggagaatttt gaccaagtag gtataataat gcttactgct aaagctcaag aagatgataa
     4861 aatagaagga tttatctcag gagcagatga ttacatcata aaaccattta gtataaaaga
     4921 gcttttagtc agagtttctg ctcttcttag aagagtagca aaggatgatt caagtgttaa
     4981 gtcgagtgag atagtttctc caccatttat acttgatata gacaaaagaa aattatttaa
     5041 aaatggaaag gaaattgagc ttacaccaac tgaattttca atagtgaaat atctaatatc
     5101 aaatgctaag cagtcgttaa gtagagacca gatattagac gaagtatggg gaactaacta
     5161 tttatatgat tttaaaatag tagatgtaaa tataagaagg ataagaaata aaatagaaga
     5221 tgacccatca aaaccaaaat atatacaaac tatttggggt tatggatact gttttagaaa
     5281 ggaagaataa tagtgttaca ttttgaaggt ctgagaaaaa aagtaataaa aaactatttt
     5341 ataataatta ttataatggt tactctgttt gaaggattgt tcatgtttta catacaaaac
     5401 tactattatg attctgtcaa acagctactt gaatctgaaa taaaatatgc tgatgaatat
     5461 aatgctatta caatggaaac tacaagtttt gagaaaaaag taaaaaatat atttgataaa
     5521 caacccttaa ctaaaaattc agaatttgga atttcaataa tagataaaga taaaaatatt
     5581 atattagacc aatatggttt taaaagtaaa gaaaaagcaa actatgaaga tgttaacaat
     5641 gcattaaaag atataaaaac taaaaattta acaccttata cttatagaat accagataca
     5701 ggggagcatg ttatgagtat ctccttacca cttaaggtaa ataatataat agaaggtgtt
     5761 gttagatata cagtatcatt agatgctatt gataatgcaa tattaaagca agctacatgg
     5821 cttatattag caggaatatt tatacttatt atagctatac taataagtct taaatttgct
     5881 gagactctta taaaaccatt acgagagcta aagaaatttg caaatgaatt ggctgtagga
     5941 aattataata taaaattaga aaagatgaag attgtagatg atgaaattgg tgatttagca
     6001 cagacatttg aacacatggc acatgagatt gacaaaagtg aaaaattaaa agaggaattt
     6061 atatcatctg tatctcatga actaaggact cctcttacat ctataaaggg gtggagtgaa
     6121 accttaggtt atgaaagtat aacaagagaa gaactagact taggtttagg cattatacaa
     6181 gatgaaacag aaagacttat aaaactagtt gaagaattat tagacttttc aaggctttct
     6241 tcagacagga taaaacttca tgttgatata gttgatgttg aaggtttaat tgtaggtgtt
     6301 gtaaatcaac ttaaagttaa agcagctgaa aaagatatat cacttttatt tgaatttgaa
     6361 aatgaattta tagagaacat tcaaggagat aaaaatagat taagacaggt tctcataaat
     6421 ttaatacaaa attcatttaa atttacgagt caaggtggtt acataaaagt tgtagcttct
     6481 caagatgaag agataacaac catatcagta gaggataatg gttcaggtat agaaaagcaa
     6541 aatttaaata aagtgttaga taaatttttc caagaagatt ataataaggc tggtagtgga
     6601 ttaggactag caattagtaa tgaaattgta aaacttcatg gtggaagaat gaaaatagaa
     6661 agtgaaaaga atgttggaac aaaaataact tttaatataa aaaataaatt tgctaaacaa
     6721 gcataaattc ttagaaagag gattaagatg agaaacataa aaatgatagt agcatacgat
     6781 ggttcaagat ataaaggata tcaaaaatta ggtgacaata atatgactat tcaagaaaaa
     6841 cttgaaaatg ttttaagtaa aatgactaat gaaacagtgg agataatagg ttctggaaga
     6901 actgatatgg gagctcatgc aagaggacaa gtggtaaatt ttagaactaa ttgtatggat
     6961 tctttggata aaattcaaaa atatttatat gaatatttac cagaagatat agttgtaaaa
     7021 actgttgaag aagttgatga aagatttcat tcaagataca atgtaaaatc aaagacttat
     7081 atgtataaaa ttgacaataa taagtatcat aatcctttta taagaaaata tgctactcat
     7141 gtaagtaaaa aattagattt agatagaatg agaaaagcaa gtgagtattt agtaggagaa
     7201 catgatttta ctagttttgc ttcttctaaa tctaagaaaa aatcaaatgt aagagaaatt
     7261 tattctataa atataaaaga agatgataat gttatagaaa tatatgtaga aggaaatgga
     7321 tttttgtata acatggtaag gataatagta ggtgctttga tagatgttgg tctaaaaaga
     7381 agagctccac aagatattaa gtatatgctt gaatcaaaag atagatgtca atcatcagat
     7441 actgcaccag ctaaaggact atgtctttgg aaagtaacat attaatcaat tatataaaac
     7501 tctctttaaa ataaaaataa aataaattat atagttgaca taaatggaaa aataaactat
     7561 tatatatttt ataagagaga tataaaactt tatatttaaa tcctgtgaga aagagagtaa
     7621 cttctatgtg ttttatagag agctgaggat ggtggaagct tggcaaataa gtattagtga
     7681 aaagaacttt ggaggatact aattgaattt agtatgttag taggtaatct cgccttaaga
     7741 gaaagagtgg ataagtttat cttatcaatt agagtggtaa cgcggatata tttcgtctct
     7801 tggtttttcc aagaggcgtt ttttaatata tttaattatt agtgtttatc tggtatgttg
     7861 aacatttact aattgattag ctaagtttat caataagagt ggtaccgcgg atatttcgcc
     7921 tcttagtatt ttaaaatact aaggggtttt tttagtatta aaatgatttt atgtgagtct
     7981 aaattctcag agtcattcaa tattaagaat ttctataaaa taaaaattat aatttaagat
     8041 tgggaggaat taaaaatgaa ggaaaaagta gtattagcat attcaggagg acttgacaca
     8101 tcaatcataa taccttggtt aaaggaaaat tatgaagata tagatgttat agctgtttgt
     8161 ggaaatgtag gtcaggaaga taaaatggaa gatgtatatg aaaaagcttt acaaagtgga
     8221 gcatcaaagg catatgtgga tgatataagt gaagaatttg taactgaaac tatatttaaa
     8281 gctgtaaaag cagaggctaa atatgaagga aaatacttat taggaacttc tttagcaaga
     8341 cctataatag ctaaaaaatt agttgaagtt gctcataaag aaggtgcaaa atatatatgc
     8401 catggatgta caggaaaagg taatgaccaa gttagatttg aagctacaat tgcagctctt
     8461 gacccaacta taaaagttat tgcaccttgg agaatttggg atataaaatc aagagaagat
     8521 gctatagact atgctgaaaa acataatata aaggtaacag caactaaagc taaaatatat
     8581 tcagtagatg ccaacctttg gcatgtttca acagaaggtg gagatataga gcacctagaa
     8641 aatgaacata aaaaagatgt ttataaacaa tgtgtagacc cagaagatgc atgtgatgta
     8701 gctgaatatg tagaagttta ctttgaaaaa ggtgtaccta aaaaggtaaa tggcgaagaa
     8761 ttatctccag ttgcactgat tcataagtta aatgagttgg gttgtaaaca tggaattggt
     8821 gttatagata tagttgagaa tagacttgtt ggtatgaaat caagaggtat atatgagact
     8881 ccaggaggaa caatccttta tgaagcacat aatattttag aaagtgctac tttagacaaa
     8941 gatacattac atttcaaaca aatggtatct tataaatacg gagaacttat ttacaatgga
     9001 ctatggtatt gtaaattaag agaatctata gatgcattta tggaacaaac tcaagataat
     9061 gttacaggaa cagtaaaagt taaactttac aaaggaaata taaaacctgc tggaatattt
     9121 actgaaaatg ctctttatga tgaaggaata tcttcttttg gaaatagtga actttatgac
     9181 cacaaagatg cagaaggatt tattaattta ttcactttac cattaaaaat cagagctatg
     9241 aaagctggaa aataataaaa taaattattt aagagtgtat aaaaacgatt tttaggtttt
     9301 tatatgctct ttttttattt gaatttatta aattatacag taaatagtat aaaaaaatat
     9361 attatagttc caaatggctt aataatgtga aaatataaga cctaaaatat aaattttata
     9421 aatacaatag ttattgactc tctcattgta agagggttta tactgaatct aatgaaaatt
     9481 tatagtgagg agatagatta tatgagaaaa ataattgaaa ttaaacatca ttcacatgat
     9541 tatgagtgta tgtggaatgg tatagaagat ttatatataa ataaaaccgg tgaatacctt
     9601 ccaaacgatt ttttcttttt actgtcaggt tttggttcat tttgttatat gaaaacaaat
     9661 aaagctgatt tgaaaagaat ggtagctttg ggagatggaa ggacaaaaca gatgtataaa
     9721 tttttagcac caattgttgg atttgaatac aaacatcatg agtttaaaaa gtatgagcaa
     9781 gcattaaaga aagcaaaatc tgaaattgat gatggatatc cagttatttt aggagcttta
     9841 gatatgtatt atctaccata ttataagaag ctatatcata aagaacatat tccttttcat
     9901 tatatattaa tggtaggata tgatgatgaa ggaatatatc tgtatgattg tggtagaaca
     9961 gaattattac atctttctta tgataaatta cgtgaaagca tgaattgcaa ttcccctgga
    10021 ttaagcaaag aaaatactat ttgcacaata agaatgaata cttcaaagaa taaatataac
    10081 attgctagag aagctattgc tataaagcgt gatatgtttt taaatccacc taaaggattt
    10141 ttgggatata aaggttttga aaagtttatt aaagagttgc cacagtggaa cactgaattg
    10201 gataaggatg attatgataa gattttgacc aatatggtta tgttttttgg aacagtacca
    10261 acaattccaa atgcaatcaa aggaattaaa gaaccagata ctgttcaatt taaaggtgga
    10321 tttgataaaa tgagtagaat gctcaacagt attggggagg aatacaaaaa caactctttt
    10381 atacaagtag ctgatatttt tgataaaact gctattataa ttgagaaaat atccaatatt
    10441 ataatagatt acttaactca aacatgtgat gatacagaac aacttccgtt attgttctct
    10501 gaggtcttag agcatatgaa aacaggatat ttaatcttgg atgtataaaa aatatattgt
    10561 tgaccctaac attacgtaat agtgtaatat gaaaatatag cttaaatata ttagtaggta
    10621 ttgatggctg taaaattaaa atttgaggtg tggatatgag aacagtgaaa caagtttctg
    10681 atttaactgg aataagtgtg agggcattac attattatga tgaaataggt cttttaaaac
    10741 caaataaaat tacagatgca ggatatagac tttatgatga tgaatctatt aaaactcttc
    10801 aacaaatttt attttttaag gagattgata ttcctttaag agaggttaag gaaataatgt
    10861 caagccaata ttttgataag gttgaagctc taaaaaatca aaaaaaatta cttattttaa
    10921 aacgaaagag actggatgaa ttgatagagc ttataaatca aactctaaga ggagaaggaa
    10981 atattgattt taaagagttt gatatgagcg agtattttaa tgttttagaa gaatttaaaa
    11041 gagagcatag gaataaggta attaaaattt atggtagtgt agaaaaatac aatgaatata
    11101 tagaaagagt taagtctaat gaagagaaaa ttgctaaaat ggctataaaa caatatggaa
    11161 ctattgagaa gtttgctaaa gctataaaaa caaattttag cagtgatata ttgaatttag
    11221 gagaaaaatt tgatagatat aaaaatgatt gtttaaaaga aaaacatcca aaattaaaag
    11281 aattatatag aaagcttgta gaagatttaa gtaggaatcc ttcttcaaca gaccttcaag
    11341 aaatagcaaa agcgataaca gatatatcta aaaaagatta tgaaattttc tctatggata
    11401 ctggtgatga caactggtat tatatggttc aaaattatct agtaaatcct atgtggatag
    11461 aagaagtaga taaaaagtat ggaagtggag caggaaagtt tattggacaa gtactaaaga
    11521 cttatctaag agatagaaaa ccaaagataa atacattgta tgaaaaactt gtagaagatt
    11581 tgagtagaga ttgttcttca agggaagttc aaagcattgt tgaagaaata gacaatgaaa
    11641 tgaaaagaag taatgaattt tataaaatag acaatggtga aagatacttt gattatatgt
    11701 cagagcttta tttacaagat tctaactata taaaagtaac tgataagaat tatggtgatg
    11761 gtgcatctaa gtttattgga gaagctttta agatttattt tgataataat aattgttgaa
    11821 aatttggaag taaaaaatat gtaagtttta taaaagcaca aaaataagga tgtagattag
    11881 ctccatctat atccttattt aaagttatta aaatatatag tttacatcaa acttaacact
    11941 ttcaataata tttcccaaat atgtttttat actttcaact tcttctaaag attttaattt
    12001 attttcagta taaattgctt tgtccagaat attaaacctt aatcctattt catcaaagta
    12061 ctcatgattt aaaactttgt accaatggtt tttttcttta ttccaactcg tagatattga
    12121 atcagcttct ttttgagctt tttcccaatc ttcattttct atagattttt ctaaaacaga
    12181 tatattgtct ttatatcctt ctgtaaaatc atatagttta ttgttaacgt aaaatccaaa
    12241 taatacaaat aagatagtcc atagtataac aaatgttgta gatttcaata ttaatcaccc
    12301 tttttatttt gaataaatat tttgtcattt tcatctaaaa cacaaataag aacatcttta
    12361 aaagtttcta tgtgattaga ttttaaaata cccattaacc agttagtatc tttttgagct
    12421 atgtctagat ttttatttat tattctacca tccagtataa gtgggatagg taaatgatta
    12481 aaagctcttg gaggagtact attgtagctt gatgctggta caacacttag attaccatca
    12541 gtctccaaaa tagcatattg tacatctttt aggttaaagt atccttgaat cctaagttgt
    12601 tctaataatt catctatact aattctttct tttttaagct ctttatatac aatttttcct
    12661 ttatctatta atacagaagg tttacctgat aaaaatgaac ttaattttct gctttttaat
    12721 gataagaatg aaattagagt ctgcatgatt acaagtccag atattgctgc aacaccattt
    12781 atgattggta tattattatt ttccattggg acagatgcaa cttctgcaat taatagtgtt
    12841 ataactaaat caaaacagtt catttcagct atttcacctt ttcccatgac tctaagtgca
    12901 attagcactg ttatgtataa tataatactt cttattaata ctactgtcat atctatcaat
    12961 tactcc
//
LOCUS       DAEPKC010000110        12504 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.110, whole genome shotgun sequence.
ACCESSION   DAEPKC010000110 DAEPKC010000000
VERSION     DAEPKC010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12504)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12504)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12504
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.110"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            503..865
                     /locus_tag="KR294_003180"
     CDS             503..865
                     /locus_tag="KR294_003180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBH0241236.1"
                     /translation="MENKILIVDDAIFMRMIIKEALSKSGYNNLIEANDGEEACNIFK
                     YEKPDLMLLDITMPKKDGLEVLREIKKLDSSAKVVMCSAIGQENMIVEAIKLGALDFI
                     VKPFKTETLVKVVDNALK"
     gene            930..1547
                     /locus_tag="KR294_003181"
     CDS             930..1547
                     /locus_tag="KR294_003181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheC"
                     /protein_id="HBH0241237.1"
                     /translation="MINYLELDDVHIDALREIGNIGSGNAITALASMINSNVEVLIPM
                     VKILEYNEATNLLGGPENKVVCILLDMKGDINGMFMFLLDESITQLMLSSLFNKEEAF
                     LDEIEAIEISAIKEIGNIMASSYVNAIASMLNMTISVSIPDICIDMVGAVLNVPMIRF
                     SDVGDKVLFIENKFKMSDNYFTSHILMIPEMSSLKEILVRLGLEV"
     gene            1544..2029
                     /locus_tag="KR294_003182"
     CDS             1544..2029
                     /locus_tag="KR294_003182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheD"
                     /protein_id="HBH0241238.1"
                     /translation="MNREIVVNIADMKIAYRPNVLVTYALGSCVGVCLIDKVAGIGGM
                     LHVMLPYSKDAINIENKCKFADTGINELIKSMENIGANRIYIKAKIAGGAQMFLGSSN
                     SVIASIGHRNVEAVKKTLLGLNIPILAEDTGMNYGRTIRFYTETGELLVDSINKGKKK
                     L"
     gene            2072..2590
                     /locus_tag="KR294_003183"
     CDS             2072..2590
                     /locus_tag="KR294_003183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-binding chemotaxis protein CheW"
                     /protein_id="HBH0241239.1"
                     /translation="MRFPDDPYLDYGLIDEGIKYLKFKVDEQDFGVELEKIIEITGNQ
                     EIIFIPELPTYSKGIINLRGKIIPIIDMRLRLKKDELMTTNCMYIVVTEIKDLVVGFV
                     VDRVDDIVSLEKSKISPPPRVTIEYSDYFVSGVGELEGKIITLLDLEKLLTDKDEVLI
                     DELINGFDCTIM"
     gene            2726..3685
                     /locus_tag="KR294_003184"
     CDS             2726..3685
                     /locus_tag="KR294_003184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HBH0241240.1"
                     /translation="MKNKQQGTILVVDDSVLMCDLIDKTLTKDNFKVKKAFNAIEAKE
                     FIEEFIPDIILLDIILPDNSGFEFCKEVKSNARTADIPIIFITSKNTDTDIVKGFGVG
                     AIDYMVKPFSMTELKARVIAHLEVKKSQDKLKKINNELESSLEKLNRLVVRDYLTGLY
                     NRRHIINQLMEQRRINKYSETSISLILGDIDDFKVINDTYGHEAGDFVLTVISSIIKK
                     NCRQIDTVSRWGGEEFLIMLTNTPIEGAKILSERIRKEIKEFDFNYKEHKIKCTITLG
                     VVEVNSNISLEENISLADKAMYEGKNLGKDCSVVSTMKGLKKI"
     gene            3711..5414
                     /locus_tag="KR294_003185"
     CDS             3711..5414
                     /locus_tag="KR294_003185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing protein"
                     /protein_id="HBH0241241.1"
                     /translation="MKREVKLSKLAIVLLIIIVLAVLAGIFSSISSYKAFEKVEKSIN
                     DMNNLRTQSQYIKDTTREISDVLRRYVFTGEKKNKDIYEKELYGKTRESALNKLEKIG
                     LTKSESNKILEAKEISDSLVPTEQSAIKAVESNDKSKAQSIIFGSDYINSQEKMDSLI
                     NEFQEDIVTRSNSKIVEVKKELQSLILRTIFILSLLIILTIIEYTVIKLKIVIPINKV
                     EKHFSRIASGDLRTSIDVEESKSEIGLLVSSVKKMQSMLLNYIDLIDSTLTSIAKGDL
                     RVEIDQEFIGDFKSIKISLESIINSFNGDFSEINLSAEQVASASEQVAAGAQALSQGA
                     TEQASSVEELASTINEISDGIKKCADSASLACEVSDQSASQVGFGSRCMDDMMTSMGE
                     ISEKSSEISKIIKTIDEIAFQTNILALNAAVEAARAGQYGRGFAVVADEVRSLAGKSA
                     KAAQNTAILIEEAIKTVENGVRIAKETANALDLVVNGVEKTTNYINGISSAVHSQEVA
                     ITQILSGIEQISIVVQMNSATAEESAAASEEMSAQAQILKELVEKFHLKESEVRESSW
                     V"
     gene            5627..7729
                     /locus_tag="KR294_003186"
     CDS             5627..7729
                     /locus_tag="KR294_003186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheA"
                     /protein_id="HBH0241242.1"
                     /translation="MRQMLDMFIFETSLLLEQLDEIMIQIEKEKVFTHNNINETFRIM
                     HTIKGSASMMGLDNISALAHSVEDLFYAIREGKIEVLDNDLLFDLVFQSLDFIRRDID
                     ELQSRGCISSDYSNFIEGIEEYVSTLELSSSMKSKDNANLESTDEKEVIDSNFEYKEG
                     SDVVKIIFEQGCMMENVRAFMLVFELRDYCEFIDFYPKDVETNAESTEYIKSYGFYIQ
                     FVAKEDKAIVYKTIEDNLYVKEYINISKKEIEMKNTSNNDAVENKLKDNNKVSKSYQN
                     NYTEDEIQEDVLNEKTDMEKDSLSEENEHLPISKQSIMSVNLEKLDLLQNIVGEIVIM
                     ESMVVNSVNSTGVDIDNFNKATRQLHKLTDELQDIVMSMRMIQIAGVFQKMHRIVRDM
                     NKKLDKNVELITIGAETEVDKSVIDNLAEPFMHLIRNAMDHAIEPIEERIAKGKEEVG
                     KIVLSAENLGGEAVISISDDGRGIMRDKILAKAKEQGLLKHQSNEYTDDEVNSLIMTP
                     GFSTKESITEFSGRGVGMDIVRKSIEKVGGSIEVKSKQDEGTTFTIKIPLTLSIVEGM
                     KFKVGDSLFTLPISSIRRTFKLTDLNQIITEGNKTELITIYGACIPIIRLHKIYNIQT
                     KVTNLMNGNMIIIENEHKAVCIFVDEIIGNQQVVVKPFPVYFNRFNIKNKGLSGCTIL
                     GDGSISLIIDADSIIEIY"
     gene            7742..8182
                     /locus_tag="KR294_003187"
     CDS             7742..8182
                     /locus_tag="KR294_003187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheW"
                     /protein_id="HBH0241243.1"
                     /translation="MAKDEIIKQVLTFYVNDVIYGIELENVIETIRFQSITYVPCLPT
                     YISGVINLRGRIIPVINMHIKYNLPKADYNERTCIIITKVDEYQVGIIVDKVVDVIHI
                     ENLNLLETTNSNNTNINKDIKEIAKVEDNSILILDIRKFLINSI"
     gene            8218..9021
                     /locus_tag="KR294_003188"
     CDS             8218..9021
                     /locus_tag="KR294_003188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-glutamate O-methyltransferase CheR"
                     /protein_id="HBH0241244.1"
                     /translation="MIKLTDEEFIVLVNHVKKEYGIDLSKKRALIEGRLYNTMIEKKL
                     SSFSQYMNLLFKDKTGNEAINLINRLSTNHTFFMREPQHFEFIQNSILPFWEENNKIR
                     NINIWSAGCSSGEEAYSIAMTLDDYFGYNKELWNIKIIATDISTNSLEKAKRGIYIES
                     NVNNVPELWKKKYFIDNKDGTFKICDKIRKSVIFKPFNLMNDFSYQHFDLIFCRNVMI
                     YFDLKTREELINKFYNATKKDSFLFVGHAEVINRSSTKYKYVKPAIYKR"
     gene            9061..9657
                     /locus_tag="KR294_003189"
     CDS             9061..9657
                     /locus_tag="KR294_003189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheB"
                     /protein_id="HBH0241245.1"
                     /translation="MERFNNMVIAIGASVGGTEAILEIIKDLPKSTPGIVVVQHMPAI
                     FTYMYAQRLDKQCIMNVREAKNNDRVEQGNVLIAPGGYQMKLCTDKQGYYVTCEKGER
                     ISGHCPSVDVLFDSVAEVAGKNSIGIILTGMGYDGASGLLKMKENGSFTIGQDENSCI
                     VYGMPMVAFDRGSVMLQLPLGEISNCLIRHINILKQKD"
     gene            9763..10626
                     /locus_tag="KR294_003190"
     CDS             9763..10626
                     /locus_tag="KR294_003190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 and DUF4163 domain-containing protein"
                     /protein_id="HBH0241246.1"
                     /translation="MKFFKVDTKAKVLRYVFVLTLTIMAVLAIKHDYKYNNLRKDASI
                     NLNSNKEAVTVMSNQSLPKGNTNSKQTLSVSTIGSKTIVKNDEYLESTINMPVITNSN
                     KIVERSTNDKIKNDIFEFYNKSYKEAKQYLKDNPDEKNKFVANVDFELKKNTDSALSI
                     KVRYYTYSGGAHGFYQDIAYNVDMRTGKFLELMDLFKDNTKYKEVIDEEIKRQIAELE
                     KKDEENIGIYNFKGIKENQNFYLQDENLVVYFDLYDITPYAAGIPEFSINKALISSML
                     KPEYVDLFDLK"
     gene            10693..11682
                     /locus_tag="KR294_003191"
     CDS             10693..11682
                     /locus_tag="KR294_003191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HBH0241247.1"
                     /translation="MLLLKKDDIKKVFTMRDAIEADKEAFRIYCEGKSVNPLRTNISV
                     PSQDASMLFMPGYVEELGCGGIKIVSVFPKNAQKGKPVIPATVLLLDGETGEVSAVLD
                     GTYVTQIRTGAASGAAIDVLAKKDSKIGALIGLGGQGEPQLEAMIEARNLDEVRVFSR
                     NKESREKFAEEMNLKLSKYNTKIVAVESSDEAIDNADVIVLATPSKQPVLNGNLVKKG
                     ALISAVGSYMPDMQELCPNCLTRASKIFFESTDAVLSESGDILIPLKEGKISKDDFSG
                     DLGNVINGTIPGREDDDEIIVFKTVGIGVQDVVTAKRIYDKAKENGIGIDWKW"
     gene            11774..12385
                     /locus_tag="KR294_003192"
     CDS             11774..12385
                     /locus_tag="KR294_003192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBH0241248.1"
                     /translation="MKMVKKLILSTIMALVLVLTIGCSNAEEKVKSNFEANLAALEMY
                     KYDEKGISDALTEAEYKQIQTYNSKDKVSMIAQLTPLYGKENAEKIYETIVKLIQGVE
                     KTVTVESSSKDKITLKVVSKALDTSKVMSEANTLVKSYVTDEKNYDKKEKEVQDDMTK
                     MIIDLYNKKPTKEVTTMITYTKKDGKWQPPSNIQKLCEGIYTI"
BASE COUNT         5065 a         1226 c         2334 g         3879 t
ORIGIN      
        1 acacattaga atacttctgg atttatgagt atacaatttg aaaaatataa aaaataatgt
       61 ataaagctaa atctaattta atcgataata catatagaga aatataatta agtaaataaa
      121 caactatcta ttagatattg agaaagtcaa atcctatatg aatctacaga aatgatttta
      181 atgaatctga aaattttttt tatacaaaca taaaaaaggt ataaagttgt tttattataa
      241 tttaattact tttgataact ttttatgttt tatacaatta tatttttaat aactcgtcaa
      301 aacgccaaac atatattaca atagatatat aagttttttt gttgacaaat tatgttaaga
      361 gaattaagta taatatggca taaataatta cttttattta tcaatgaaat gtatttattg
      421 tgtagcgaaa aatagtcaga tagtatagac aataactgaa gataaaagcg tttattgttg
      481 tacatatgga ggagttagtt ttatggaaaa taaaattttg atagtagatg atgctatttt
      541 tatgagaatg ataattaaag aagctctgag taaaagtggc tataataatt taatagaagc
      601 aaatgatgga gaagaagcgt gtaatatatt taaatatgaa aagcctgatt tgatgttgct
      661 tgatattaca atgccaaaaa aagatggttt agaggtgcta agagaaataa aaaagttgga
      721 ttcaagtgct aaggttgtaa tgtgctctgc aataggacaa gagaatatga ttgtagaagc
      781 cataaaactt ggagcgttag attttatagt gaagcccttc aaaacagaaa cattagttaa
      841 agttgtagat aatgctttaa aataaaagtg taaatataca ctaatacaat gaaaagcaaa
      901 taaatgcaat aataaaggga ggggtttata ttataaatta tttagaactt gatgatgttc
      961 atatagatgc tcttagagaa attggtaata taggctctgg gaatgcaatt actgcacttg
     1021 catccatgat aaatagcaat gtagaagtat taatacctat ggtcaagata cttgaatata
     1081 atgaagcgac aaatttgctt ggtggtccag aaaacaaagt agtatgtatt ttactcgata
     1141 tgaaaggtga tatcaatgga atgtttatgt ttttgttgga tgaatcaata actcaactta
     1201 tgctaagttc tctttttaat aaagaagaag cttttttaga tgagattgag gcaattgaaa
     1261 tttcagcaat taaggaaata ggaaatatta tggcaagttc atatgtaaat gctattgcat
     1321 ctatgttaaa catgactata agtgtttcaa ttccagatat atgtattgat atggttggag
     1381 ctgttctaaa tgtacctatg ataagatttt cagatgttgg tgacaaagtc ttatttatag
     1441 aaaataaatt taaaatgagt gataattatt ttactagtca cattttgatg attccagaaa
     1501 tgagctcact taaagagata ctcgtgaggt tgggattaga ggtatgaata gagagatagt
     1561 agtgaacatt gcagatatga agatagccta tagaccaaat gttttagtta cttatgcact
     1621 tggttcttgt gtaggagtat gtttgataga taaagtagct ggaattggtg gaatgttaca
     1681 cgttatgttg ccatatagta aagatgctat taacattgaa aataagtgta aatttgctga
     1741 cacaggaata aatgagctca ttaaatctat ggagaatata ggtgcaaata gaatatatat
     1801 aaaagcaaaa attgctggag gtgctcagat gtttttagga agtagcaatt cagtaattgc
     1861 aagtatagga cataggaatg ttgaggcagt aaaaaaaact cttttaggat taaatattcc
     1921 aatattagct gaggatacag gtatgaatta tggtagaaca atacgttttt acactgagac
     1981 gggtgaatta cttgtagatt caataaataa aggtaagaag aaattataat atatatttca
     2041 tagaaagtgt attttaggag ggaggtatta aatgagattt ccagatgacc catatttaga
     2101 ttatggacta attgatgaag gaattaagta tctaaagttt aaagtagatg agcaagattt
     2161 tggggttgaa cttgaaaaga taatagaaat tactggaaat caagaaatta tatttattcc
     2221 agaactacct acatattcta aaggcataat aaatctaaga ggaaaaatca ttccgataat
     2281 agatatgcgt ttgagactta aaaaagatga attaatgact acaaattgca tgtatatagt
     2341 agtaactgaa ataaaggact tggtagttgg atttgtggtt gatagagttg atgatatagt
     2401 aagcttagaa aaaagtaaaa tatcacctcc accaagagtt actatagaat attcggatta
     2461 ttttgtaagt ggagttggag aattagaagg taaaataatt actttactag atttagagaa
     2521 acttttgaca gataaagatg aagttttaat agatgaatta atcaatgggt ttgattgcac
     2581 tatcatgtaa tatagggatg tagttggagt gttattataa aaagattgtg atgagaacat
     2641 ttaagaatat agtggtataa ttattaagta taaaaatttt aaatcattaa aatttgaata
     2701 tattatgttt aagagaggtt tgtatatgaa aaataagcaa cagggaacaa ttttagtcgt
     2761 tgatgatagt gttctgatgt gtgacttaat agataaaaca cttacaaaag ataattttaa
     2821 ggttaaaaaa gcatttaatg caatagaggc aaaagaattt attgaagaat ttataccaga
     2881 cattattttg cttgatataa ttttaccaga taattctggt tttgagtttt gtaaggaagt
     2941 aaaatctaat gctcgtacag cagatatacc tataattttt ataacttcaa aaaatacaga
     3001 tacagacata gtaaaaggat ttggtgtagg agcaattgac tatatggtga aaccttttag
     3061 tatgacagaa ttaaaagctc gtgttatagc tcatcttgaa gtaaagaaat ctcaagataa
     3121 actaaaaaag ataaataatg aactggaatc ttctcttgaa aaattgaata gactcgttgt
     3181 aagagattat cttacaggtc tttacaatag gcgacatata attaatcagc ttatggagca
     3241 aagaagaatt aataaatata gtgaaacatc aatatccctt atccttggtg atattgatga
     3301 ctttaaggtt atcaatgata cttatgggca tgaagcaggg gatttcgtgt taacagtaat
     3361 atcaagtata ataaaaaaga attgtagaca aattgatact gtatcaagat ggggtggaga
     3421 agagtttttg ataatgctca caaatactcc aatagaaggt gctaagatac tttcagaaag
     3481 aatccgtaaa gagataaagg agtttgattt caactataaa gaacataaaa taaagtgcac
     3541 tattacatta ggagtagtag aagtaaactc aaatatatca ttagaagaaa acatatcctt
     3601 agcagataaa gcaatgtatg agggtaaaaa cttaggaaaa gattgtagcg tagtgagtac
     3661 aatgaaagga ttaaaaaaga tataaactta ctttatgaag gagtacagat atgaaaagag
     3721 aagtaaagct ttctaaatta gcaattgtat tgctgattat tatagtattg gctgttctag
     3781 cagggatttt ttcttctatt tcatcttata aagcatttga aaaagtagaa aaaagtatta
     3841 atgatatgaa taatttgagg actcaaagtc agtatataaa agatacaact agagagataa
     3901 gtgatgtatt aagaagatat gtatttacag gagaaaaaaa gaataaagat atttatgaaa
     3961 aagaattata cggaaaaaca agagaatcag ctttaaacaa attagaaaaa attggtctta
     4021 caaagagcga gtcaaataaa atcttagaag caaaagaaat atcagattct ttagtaccaa
     4081 cagaacaaag tgcaataaag gcagtcgaaa gtaatgataa gagtaaagct caaagtataa
     4141 tttttggtag tgactatata aactcccaag agaaaatgga ttctttaata aatgaatttc
     4201 aagaggatat agttacccgt tcaaattcca aaattgtaga ggtaaaaaaa gaattacaaa
     4261 gtctaatatt aagaacaata tttatacttt cccttttaat aatattgaca ataatagaat
     4321 atacagtaat aaaattaaaa atagtgattc ctattaataa agtagaaaaa cacttttcaa
     4381 gaattgcatc tggggactta agaacaagta tagacgttga agaaagtaaa tctgaaatag
     4441 ggctattagt gagttctgtc aaaaagatgc aaagtatgct tttaaattac atagacctta
     4501 tagacagtac attaactagt attgcaaaag gagatttaag agtagagata gaccaagaat
     4561 ttataggtga ttttaaatca attaaaatat ctttagaaag tataataaac tcttttaatg
     4621 gtgatttttc tgaaataaat ttatcagcag agcaagttgc aagtgcttca gaacaagttg
     4681 cagcaggtgc acaagctctt tcacagggtg ctactgaaca agctagttca gtagaagaat
     4741 tagcttccac gattaatgag atatcagatg gaattaagaa gtgtgcagat agtgctagtc
     4801 ttgcatgtga ggtatctgac caatctgcat cacaagttgg ttttggaagt agatgtatgg
     4861 atgatatgat gacatcaatg ggtgaaataa gtgaaaaatc gagtgaaata tcaaaaataa
     4921 tcaaaacaat agatgagata gcattccaaa ctaatattct tgcattaaat gcagctgttg
     4981 aagcagcaag agcaggtcaa tatggtagag gatttgcagt tgtagcagat gaagttaggt
     5041 ctttggctgg taaaagtgca aaagcagctc aaaatacagc tattctcata gaagaagcta
     5101 ttaaaacagt agaaaatggt gtcagaattg ctaaagagac tgcaaatgca ttggacttgg
     5161 tagtaaatgg tgtagaaaaa actactaatt atattaatgg tatttcttcg gctgtacata
     5221 gtcaagaagt agcaattaca cagattttat ctggaataga gcaaatttcc atagtagtcc
     5281 aaatgaactc agcaacagca gaggaaagtg cagcagcctc agaagagatg tctgctcaag
     5341 ctcaaatttt aaaagaatta gtagaaaaat ttcatctaaa ggaaagtgaa gtaagagaat
     5401 catcatgggt ttaaattatg aggtgaatat tgaagtaaga gaattatcat gtatttaaat
     5461 tatgagatgt atatatattg aagtaagaga ataattgtgt atttaaatta tgaggtacat
     5521 atagtgagat aagagaatca tcaaggattt aaattatgag atgcatatat aatagaaaat
     5581 tatttgtagg tcgtaggtga taaatgtgaa ttatattgaa ccgagtatga gacaaatgtt
     5641 agatatgttt atatttgaga caagtttatt actcgaacaa ttagatgaaa ttatgattca
     5701 aatagaaaaa gagaaagtat ttactcataa caacattaat gaaactttta gaataatgca
     5761 tacgataaaa ggttcagcat ctatgatggg gttagacaat atatctgctt tagcacatag
     5821 tgtagaagac ttgttttatg ctatacgtga aggtaaaata gaagttttag acaatgacct
     5881 attatttgat ttagtctttc aatcattaga ttttataaga agagatatag atgagttaca
     5941 atcaagaggt tgtatatctt ctgattactc taattttatt gaaggaattg aagagtatgt
     6001 gagtactttg gaattatcaa gttctatgaa atcaaaggat aatgcaaatt tagaaagtac
     6061 agacgaaaaa gaagtaatag attcaaattt tgaatacaaa gaaggctctg atgtagtaaa
     6121 aataatcttt gaacaaggtt gcatgatgga aaatgtgaga gctttcatgc ttgtatttga
     6181 acttagagat tactgtgaat ttatagattt ttatccaaaa gatgtagaaa caaatgcaga
     6241 gtctacagag tatattaaaa gttatgggtt ttatatacaa tttgtagcta aagaggataa
     6301 ggcaatagtt tataaaacta tagaagataa tctctatgta aaagaataca taaatattag
     6361 taaaaaagaa atagaaatga aaaatacatc aaacaatgat gcagtagaaa ataaattaaa
     6421 agataataat aaagtaagta aaagttatca aaataactat acagaagatg agatacaaga
     6481 agatgtttta aatgaaaaaa ctgatatgga aaaagatagt ctaagtgaag aaaatgaaca
     6541 tttaccaata agtaagcaga gtattatgag tgtaaattta gaaaaattgg acttacttca
     6601 aaatatagtt ggagaaattg taattatgga atcaatggtt gtaaatagcg taaattctac
     6661 aggtgttgat atagataatt tcaataaggc aacaagacaa ttacacaagc ttacagatga
     6721 attgcaagat atagtaatgt ctatgcgtat gattcaaatt gctggtgtat ttcaaaaaat
     6781 gcatagaatt gtacgagata tgaataaaaa attagataaa aatgtagagt taataactat
     6841 aggagcagag acagaggtag ataagagtgt aattgataat ttagcagaac cttttatgca
     6901 ccttataaga aatgctatgg accatgcaat agagcctatt gaggagcgta tagcgaaagg
     6961 taaagaagaa gtgggaaaga tagttttatc tgctgaaaat ctaggcggag aagctgtgat
     7021 aagtatttca gatgatggta gaggcattat gagagataag attttggcaa aagctaagga
     7081 acaaggtctt cttaaacatc aaagtaatga gtatactgat gacgaggtca attctttgat
     7141 tatgactcca ggcttttcta caaaagaatc tataactgaa ttttctggaa gaggagtagg
     7201 catggacatt gttcgtaaaa gtattgaaaa agttggaggt tcaattgaag taaaaagtaa
     7261 acaggatgaa gggacaacct ttactataaa aataccatta actctttcta tagtagaggg
     7321 tatgaagttt aaagttggag attcactatt tactttacca atatcatcca taagaagaac
     7381 atttaaactt acagacttaa atcaaataat tacagaagga aataagacag agttaattac
     7441 aatatatgga gcatgtattc ccattataag gttacataaa atatataata ttcaaacaaa
     7501 agtaaccaat ctgatgaatg gtaatatgat aattattgaa aatgagcata aagcagtatg
     7561 catttttgtt gatgaaataa taggtaatca gcaagttgtt gtgaaaccat ttccagttta
     7621 ttttaaccga tttaatataa aaaataaggg tttatcggga tgtacaatac ttggggatgg
     7681 aagtataagt ttaattatag atgcagatag cattatagaa atatattagg ggatttaaag
     7741 tatggctaaa gatgaaatta ttaaacaagt attaacattt tatgtcaatg atgttattta
     7801 tggaatagaa ttagaaaatg tgattgaaac cataagattt caatcaataa cgtatgtacc
     7861 atgtcttcca acatatataa gtggagttat taatttgaga ggaagaataa taccagttat
     7921 taatatgcat ataaagtaca atcttcctaa agctgattat aatgagagaa cttgtataat
     7981 aattacaaag gttgatgagt atcaagttgg aattattgta gataaagttg ttgatgttat
     8041 tcatatagaa aatctaaatt tactagagac gactaattct aacaacacta atattaataa
     8101 agatataaaa gagattgcga aagttgaaga taattctata ttaattttag atattcgaaa
     8161 gtttttgatt aatagcatat agttagttct gataaattag caggaggaag tttttgcatg
     8221 ataaaactca cagatgaaga atttatagtt cttgtaaacc atgtaaaaaa agaatatggt
     8281 attgatttaa gtaaaaaaag agcgttaatt gaaggtcgct tatacaatac aatgatagag
     8341 aaaaaactta gttcttttag tcaatatatg aatctattat ttaaagataa gacaggaaat
     8401 gaagctataa acctaataaa tagattgagt actaaccaca cattttttat gagagaacct
     8461 caacattttg agtttataca gaatagtata cttccttttt gggaagaaaa taataaaata
     8521 agaaacataa atatatggag tgcaggatgt tctagtggag aagaagcgta ttcaatagct
     8581 atgactttgg atgattattt tggatataat aaagagttgt ggaacattaa aatcatagcc
     8641 acagatattt caactaactc acttgaaaaa gctaaaagag gtatatacat agaatcaaat
     8701 gttaacaatg ttcctgagtt atggaagaag aagtatttta tagacaacaa ggatggtaca
     8761 tttaaaattt gtgataagat tagaaaaagt gtaattttta agccgtttaa tttaatgaat
     8821 gatttctcat atcaacattt tgatttgatt ttttgtagaa atgttatgat ttattttgat
     8881 ttaaaaacaa gagaagaact tataaataaa ttttataatg ctaccaaaaa agatagtttt
     8941 ttgtttgtag gacatgcaga agtaatcaac agaagtagta ctaaatacaa atatgtaaaa
     9001 cctgctatat ataaacgata aaaaggtatt tttgatatat gattttttgg aggcggtaat
     9061 gtggaacgtt ttaataatat ggttattgct ataggcgcat ctgtaggtgg tacagaggca
     9121 atacttgaaa ttataaaaga cctaccaaaa tcaacaccag ggattgttgt agttcaacat
     9181 atgccagcta tatttactta tatgtatgca caacggcttg acaagcagtg tattatgaat
     9241 gtaagagaag ctaagaataa tgatagagta gaacaaggaa atgtgttaat tgcacctggg
     9301 ggttaccaga tgaaattgtg tacggataaa caaggatatt atgtaacttg tgaaaaagga
     9361 gaaagaataa gtggtcactg tccatcagta gacgttttgt ttgattcagt agcagaagta
     9421 gcaggtaaaa attcaatagg aataatactt acaggtatgg gttatgatgg agcaagtgga
     9481 cttttaaaaa tgaaagaaaa tggttcattt acaattggac aggatgaaaa ttcttgtata
     9541 gtatatggaa tgccaatggt agcttttgat agaggttctg ttatgttaca attacctctt
     9601 ggtgaaattt caaactgttt gataagacat attaatattt taaaacaaaa agattaattt
     9661 tttataaata aaaattaatc ttttattaaa ttatatggat aaaaaaccct agaaactcca
     9721 aatataataa gagagattta tatttaggag gaaaatgata atatgaaatt ttttaaagtc
     9781 gatacaaaag ctaaagtttt aagatatgta tttgttttaa cattgactat aatggctgtt
     9841 ttggcaatta aacatgacta taaatataat aatttaagga aagatgcttc aattaattta
     9901 aatagtaata aggaagcagt gactgttatg agtaaccagt cattaccaaa gggtaataca
     9961 aatagtaaac aaactttatc agtaagtaca ataggaagta aaacaatagt gaaaaatgat
    10021 gagtatttag aaagtactat aaacatgcct gtaataacaa attcaaataa aattgttgaa
    10081 aggtctacaa atgataagat aaaaaatgac atatttgaat tttataataa atcatataaa
    10141 gaagcaaagc agtatcttaa ggataatcct gacgagaaaa ataagtttgt tgcaaatgta
    10201 gactttgaac ttaaaaagaa tactgattct gctcttagta taaaagtgag atattatact
    10261 tatagtggtg gagcacatgg attttatcaa gatatagcat ataatgtgga tatgagaact
    10321 ggaaaatttt tagaattaat ggacttgttt aaggataata ctaaatataa agaagttata
    10381 gatgaagaaa ttaaaagaca aatagctgaa cttgaaaaaa aggatgaaga aaatatcgga
    10441 atatataatt ttaaaggtat aaaagagaat caaaactttt acttgcaaga tgagaatcta
    10501 gttgtatatt ttgatttgta tgatataact ccatatgcag caggaatacc agaattttca
    10561 ataaataaag cgttgataag ttctatgcta aaaccagagt atgtagattt atttgatttg
    10621 aaatagaaga ttaaattaaa tgttatgcta taatatttag catagagact tattaaaatt
    10681 gggggtataa aaatgctact tttaaaaaaa gacgacataa aaaaagtatt tacaatgaga
    10741 gatgcaattg aagctgataa ggaagctttt agaatttatt gtgaaggaaa gagtgtaaat
    10801 cctttgagaa ccaatatatc tgttccaagt caagatgcta gtatgttatt tatgccagga
    10861 tacgtagaag aattaggctg tgggggaata aaaattgtat ctgtatttcc taaaaatgct
    10921 caaaaaggca aaccagtaat tccagcaaca gtactattat tagatggaga aactggagaa
    10981 gttagtgcag tattggatgg tacttatgta actcagattc gtactggagc agcctctgga
    11041 gcagctatag acgtattggc taaaaaagat tctaagattg gagctttgat aggtctagga
    11101 ggacaaggtg agccacaact tgaagccatg atagaagcta gaaatttgga tgaggtaaga
    11161 gtttttagta gaaacaagga aagtagagaa aaatttgcag aagaaatgaa cttaaaatta
    11221 agtaaatata atactaaaat agttgcagtt gaatcatctg acgaagccat agataacgca
    11281 gatgtgatag ttttagctac tccatcaaaa caaccagtac ttaatggaaa cttagtgaaa
    11341 aaaggagctt taataagtgc agtaggttca tatatgccag atatgcaaga gttgtgccca
    11401 aactgtttaa ctagagcgtc taagatattt tttgaatcaa cagatgcagt tttatctgag
    11461 tcaggagata tattaattcc attaaaagaa ggtaagataa gtaaagatga ttttagtggt
    11521 gatttaggaa atgttataaa cggaactatt cctggaagag aagatgatga tgagataatt
    11581 gtatttaaaa ctgttgggat aggtgtacaa gatgtcgtaa cagcaaaaag aatatacgat
    11641 aaagcaaaag aaaacggtat tggaatagac tggaagtggt aaaatattca aaataattct
    11701 atagttagac aaatttatgt tataatgttg ataaataaat tttttattat tttaattgag
    11761 ggaggatgtt tgtatgaaaa tggtaaaaaa gttaatatta tctacgatta tggctctagt
    11821 tttagttcta actatagggt gttctaatgc agaagaaaaa gtaaagtcga attttgaagc
    11881 taatttagct gcattagaaa tgtataagta tgatgaaaaa ggaatttctg atgcattaac
    11941 agaagctgaa tataaacaga ttcaaactta taacagcaag gacaaggttt caatgattgc
    12001 tcaattgaca cctctttatg gtaaagaaaa tgctgaaaag atatacgaaa caattgttaa
    12061 attaattcaa ggtgttgaaa agacagtaac agtggaatct tctagtaagg ataagataac
    12121 tttgaaagtt gtaagtaaag ctttagatac tagtaaagta atgagtgaag cgaacacttt
    12181 agtaaaatct tatgtaactg atgaaaagaa ttacgataaa aaagaaaaag aagttcaaga
    12241 tgatatgaca aaaatgatta tagaccttta caataagaaa ccaactaagg aagttacaac
    12301 tatgattaca tatactaaaa aagatggtaa atggcaacca cctagtaata tacaaaagtt
    12361 atgtgaagga atatatacaa tttaatttat tttaaagaca caaaactatc ttttaagcat
    12421 ataataaaat gtttggaaga tagtttattt tattttcaaa gtataaatta tattttataa
    12481 atgatttatt ttataaataa ttta
//
LOCUS       DAEPKC010000111        11271 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.111, whole genome shotgun sequence.
ACCESSION   DAEPKC010000111 DAEPKC010000000
VERSION     DAEPKC010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11271)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11271)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11271
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.111"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(409..1125)
                     /locus_tag="KR294_003193"
     CDS             complement(409..1125)
                     /locus_tag="KR294_003193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0241249.1"
                     /translation="MNQNILVVDDDREIVDAIEFYLRPDNFNVLKAYDGLEALDILIE
                     NDIKLIIMDVMMPNLDGLKTTLKIREKRNIPIILLSAKSEDMDKIIGLNMGADDYITK
                     PFNPLELTARVKSQLRRYINLGDFSNTNNSNDTNYILKSGGLELNTDTKIVSLDGEEI
                     KMTPLEYKILTLLMSRKGKIFSSHEIYENVWNEDAYSCERTIAVHIRRIREKIEINPK
                     EPKYLKVVWGIGYKIEKLNY"
     gene            complement(1664..2464)
                     /locus_tag="KR294_003194"
     CDS             complement(1664..2464)
                     /locus_tag="KR294_003194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HBH0241250.1"
                     /translation="MTFKNKKFTINKYKILSIILVLCLILTAFSSYVNYSHKKFKDYV
                     VFYVQHQDDEVLWAGSAIVNAIKERGKNHVFVVLVSTGCGISVFDKYKKYENLTNIQK
                     SEYRNREFLASLNSLGVIRENIILLPETNTNGNTDFNYMEKIALTFEEKFKNVTHIAH
                     TYKLDDHLQHLKNGSVIQNLYNAGKIKDAKYFVKPKFADKITFNNKIVYKAHSTEDYE
                     KVKNACQQYKIVDELEYREGIGYKSDHKSFDKLLNNKDVPAILHTPNL"
     gene            complement(2778..3509)
                     /locus_tag="KR294_003195"
     CDS             complement(2778..3509)
                     /locus_tag="KR294_003195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241251.1"
                     /translation="MNIFDILRDYLLVQVDKYNLNMDMISIVSKSLSSKEAIGNTKRK
                     DFPIIVGKEIMLEADFKGAKGQAFTSTPSTFEGSLKDILSLDLHDNSHDRSLFIASLN
                     AVMKYLGKTDRTIHCKNNEPEVCAKKFPEFIKMEFGNPKVAIIGYQPAIIDNIKDFFE
                     TRVLDLNPEFVDTIQYNVKIEDGIRDYEDVISWADLVICTGSTLCNNSIINFLSLNKP
                     VYYYGTTIAGASNILGLKRLCFCSK"
     gene            complement(3496..4191)
                     /locus_tag="KR294_003196"
     CDS             complement(3496..4191)
                     /locus_tag="KR294_003196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH0241252.1"
                     /translation="MLKIKNLSLDLPNFKLQENSLNINNHEYFVLLGASGSGKTLFLE
                     TLAGRYPSAKGNVSYKENLISNLPPENRNIGFVYQNFELFPNMNVEDNIRFPLKLRKI
                     PIDEQILKANHLSKLMQIEDIKNRYPKNLSGGEKQRVAFARALIAEPDILLLDEPMSS
                     LDYITKKHISKILKDVYIKYKPTVIHVTHDISEAMFFAHKIGIMNNGKINHIFDLNEE
                     IKNKGESFFYEYI"
     gene            complement(4193..4984)
                     /locus_tag="KR294_003197"
     CDS             complement(4193..4984)
                     /locus_tag="KR294_003197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0241253.1"
                     /translation="MKNKFFTTLLTGFFAIVFLFIVSPLLMLIIKGISYVPICLKSVE
                     VQYAITLSIKTSLISTIVCLLLAIPVAYFLHITKLPFKKLIIQIINLPMSLPHLVSGI
                     ALLLLFGRMGIGDSIYKIFKLDFIFTKQGIVLAQIFVNLPLTIKILHTSLNESNEKMI
                     FVARTLGCNSWEAFRFIILPNLKTGIISATVMTWSRALGEFGAVAMIAGSTRMKTEII
                     PTSIYLNMSTGDIDIAIGIAVILIFLSLTCLMLFEIFFNREVDKN"
     gene            complement(4994..5806)
                     /gene="modA"
                     /locus_tag="KR294_003198"
     CDS             complement(4994..5806)
                     /gene="modA"
                     /locus_tag="KR294_003198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBH0241254.1"
                     /translation="MFKKLSVLALAMIISLSITACNSKENKANDESNTKVTTADDSKE
                     KETLFVYSGAGLKKPMDEIAKKFEKENNVKVEYSYAGSAQLIAQIETSHKGDVFIVGS
                     EPIYSKAFEKELVGEHKTVAHHTPAIVVPKGNPANIQKLEDLNKDGVKLILGDKESNA
                     IGKTTQKILEKNNLKSINDNVVSTAATVNEMIVQLTSSKADATIATKDSVFGNEDVEV
                     IEIAQDKNIDQLISAGIVNYSDKKDLANKFINYIESDEAKQIFKKYGFEPVK"
     gene            complement(6441..6641)
                     /locus_tag="KR294_003199"
     CDS             complement(6441..6641)
                     /locus_tag="KR294_003199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003723180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBH0241255.1"
                     /translation="MNNGIVKWFNNEKGFGFISMESGDDVFAHFSAIQTSGFKSLEEG
                     QKVSFDIVKGARGPQAENITIL"
     gene            complement(6866..7042)
                     /locus_tag="KR294_003200"
     CDS             complement(6866..7042)
                     /locus_tag="KR294_003200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241256.1"
                     /translation="MFRDKMDKCTHMLTAYIGSSYDYCDFIDTQLDDFILEYGEKVVE
                     SCLHQVMVLVSKYN"
     regulatory      complement(7096..7185)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            complement(7365..7565)
                     /locus_tag="KR294_003201"
     CDS             complement(7365..7565)
                     /locus_tag="KR294_003201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0241257.1"
                     /translation="MPKFTCNLKKYRQLKELTQEQLAEKVGVRRETIMRLEAGKYNPS
                     LKLAIDISKIVDTPIDELFIFD"
     gene            complement(7567..7917)
                     /locus_tag="KR294_003202"
     CDS             complement(7567..7917)
                     /locus_tag="KR294_003202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3796 domain-containing protein"
                     /protein_id="HBH0241258.1"
                     /translation="MIQKKFFMGFCGFLGFLSLRYFSSGNVADLTYIGFFAFFSNFII
                     SKINGDKADERYVQDEKAAMAFTGQLAIIELFILWCITIVSRNIELMCVLLSITYAIT
                     LNVYAIKLYILEEK"
     gene            8079..8268
                     /locus_tag="KR294_003203"
                     /pseudo
     CDS             8079..8268
                     /locus_tag="KR294_003203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890498.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(8745..8915)
                     /locus_tag="KR294_003204"
     CDS             complement(8745..8915)
                     /locus_tag="KR294_003204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241259.1"
                     /translation="MHVYQPKTSEYLLNTYAKSYLSSIVFLFDYITKNESGYAFFIID
                     FPFLSLDIFYKF"
     gene            complement(9304..9798)
                     /locus_tag="KR294_003205"
     CDS             complement(9304..9798)
                     /locus_tag="KR294_003205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HBH0241260.1"
                     /translation="MKNKKGFTLVELLVVIAIIGILAIVALPALFKNIEKAKIAKLEA
                     DISAIKSASLSYYADESKYTDGGMISWVKKDGKIIINGGFKDDPLADKIENLGMPYNG
                     SYLLMSSPGHEKYLELSILPEGEISKSGLDKLKSDYGSSIDIMNEQNKIDIVIKFLND
                     KSNT"
     gene            10603..10980
                     /locus_tag="KR294_003206"
     CDS             10603..10980
                     /locus_tag="KR294_003206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBH0241261.1"
                     /translation="MKEEILIEKLLRVELIVMEYLWKKDTLMPKKKIVKEIKQIYGWH
                     KSTIKILLKRLVDKRYLARYIINFQSYYKIIIDNKEYYTFKKKVLKSSKSIKIMHSLT
                     TIHKNVSKEKLDLLDEYYRNLKE"
     gene            11085..>11271
                     /locus_tag="KR294_003207"
     CDS             11085..>11271
                     /locus_tag="KR294_003207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBH0241262.1"
                     /translation="MKISKLPEAELKVMRYIWESEKVLIPREITKSMEQKYEWKDTTI
                     FTVLKRLLKKRVFRSGEN"
BASE COUNT         4199 a         1479 c         1323 g         4270 t
ORIGIN      
        1 tagattatta aattagtgtt gtaaaacatt ttattacttg taaatgcatg aaaccttaag
       61 gttaatagta tcaaagttaa tataagtgta agttctattt ttaccttaga aaaaaggttt
      121 atgacattct ctaagaattt gactttagtt tgtttatttt ttttatacaa tgtaaaacat
      181 agtatagtca ataaaaaact tgataatata atacctatgc agacaaactc taattctact
      241 tttgacaaat gtacaggagt accgaaaaaa taaaaataag ggagagcaaa ctctctataa
      301 taataattaa tattagaaaa gttattattc aaatcataaa ctgcttcaaa taatatagaa
      361 actaatagaa acagtaataa taataaaata aattttgctt tagaatcatt aataattaag
      421 tttttcaatt ttgtaaccaa tgccccacac cacctttaaa tattttggtt cttttggatt
      481 aatttcaatc ttttctctaa ttcttctaat atgaacagca atagttctct cacaactata
      541 agcatcctca ttccagacat tttcataaat ctcatgagaa gagaaaattt taccttttcg
      601 tgacataaga agtgtaagta ttttatattc aagtggtgtc attttaattt cctcaccatc
      661 taaagaaact atttttgtat ctgtatttag ctctaggcca ccacttttta gaatataatt
      721 agtatcattt gagttatttg tattactaaa atcacctaaa tttatatacc ttctaagttg
      781 agattttact cgagcagtaa gttctagtgg attaaatggt ttagttatat agtcatcagc
      841 acccatatta agacctataa ttttgtccat atcttctgat tttgcagata agagaattat
      901 tggtatattc cttttttctc ttattttaag tgtagtttta agcccatcta aattgggcat
      961 cattacatcc attattatta atttaatatc attttcgatt agtatgtcca atgcttcaag
     1021 tccatcatat gcctttaaaa cattaaagtt atcaggtctc aaatagaact ctatagcatc
     1081 aactatctct ctatcatcat ctacaaccaa tatattttga ttcaatttat taaccccctt
     1141 gaaattttat ttttaaccaa tttttatttt ataccaaaaa gaggtattag aaaacagtaa
     1201 gcccgttcat tatgaaataa aaactagtac ttttaatata ttgtcaatgc atatagtaaa
     1261 tttaaaagta tagacgccca tattaatctg aaggtaaaag tttatgaaaa tatctagggt
     1321 aatctatcac acttcttatg ttattttggt ttattaattt tttaggttta aacatatatt
     1381 aacaaatata aataacaaat gagtttcata attattaaga atttataaca aatatttatt
     1441 ttaatgtagt ttaatataaa caggtagttt aatgtaggta tgtataaagc atttaataag
     1501 gcttataggt tttaatgatg atatctttat atattttaag agatgatgaa attagatatg
     1561 ggtaatagtt gtatgagaaa aagtagtata gcacaaaaag tgctatatca caaaatctca
     1621 aataatttcc tttttataac ttaaattaaa gaataaatat ttcttataaa ttaggtgtat
     1681 gaagtatagc aggaacatct ttattattta ataacttatc aaatgattta tggtcagact
     1741 tatagccaat accttctcta tattctaatt catcaacaat tttgtattgt tgacaggcat
     1801 ttttaacctt ttcatagtcc tcagtagaat gagctttata aactatctta ttattaaaag
     1861 ttattttatc agcaaattta ggttttacaa aatatttagc atcttttatt ttaccagcat
     1921 tatataaatt ttggataaca gaaccatttt ttaaatgttg taaatggtca tctaatttat
     1981 aagtatgtgc tatatgagtt acatttttaa atttttcttc aaatgtaaga gcaatttttt
     2041 ccatgtaatt gaagtcagta ttaccatttg tatttgtttc tggtaataat attatatttt
     2101 cccttattac accaaggcta ttaagagaag ctaaaaattc tctatttcta tattctgatt
     2161 tttgtatatt tgttaggttt tcatattttt tatatttatc aaagacggat ataccacatc
     2221 cagtagatac taaaaccaca aatacatgat tttttcctct ttcttttata gcattaacaa
     2281 tagcactccc agcccacaac acttcatcat cttgatgctg aacatagaag acaacataat
     2341 ctttaaattt tttatgacta taattcacat agctactaaa agcggttaaa atcaaacata
     2401 aaactagaat aatagataga attttatatt tatttatagt aaatttttta ttcttaaatg
     2461 tcatttaatc atctcctgaa aggttgtctt agttatatta tcaaacaaag tactaaaaat
     2521 tatttcttaa atgctgaaaa atatagagta gattaatgga ataaaatttt tttattagtt
     2581 taaaataaag aaaacattta tgtataagac taatcaaaat attaatgatt gataggaatt
     2641 gagatttaaa gggattgtac atttattcgg gattcatttt aatagaattt tactttagta
     2701 cttagaataa aagtaataac tttttaaatt taaagagtac acatatatat ttgtgtactc
     2761 cttgatgata tgattgctta tttactacaa aaacagagtc tttttaaacc taaaatattt
     2821 gatgcaccag ctatcgtagt tccataatag taaactggtt tgttaagtga tagaaaattt
     2881 ataattgagt tattacataa tgtacttcct gtgcaaatca ctaaatcagc ccaagatatt
     2941 acatcttcat aatctcgtat accatcttca atcttaacat tatattgaat agtatccaca
     3001 aattcaggat ttaaatctaa tactcttgtt tcgaaaaagt ccttaatatt atcaattatg
     3061 gctggttgat atcctataat tgctactttt ggattaccaa attccatttt tataaactca
     3121 gggaattttt ttgcacatac ctctggctcg ttatttttac aatgaatggt tctatccgtc
     3181 ttgcctaagt atttcataac tgcatttaat gatgctataa aaagacttct atcatgagaa
     3241 ttgtcatgta aatctaatga taatatgtct tttaaagaac cttcaaatgt agatggagta
     3301 gaagtaaatg cttgtccttt agctccttta aagtcagctt caagcattat ttctttacca
     3361 actataattg ggaaatcttt acgcttagta tttccaattg cttcttttga agatagagat
     3421 ttggacacaa tacttatcat atccatattt aaattatatt tatcgacttg tactaataga
     3481 taatctctca aaatatcaaa tatattcata gaaaaaagat tctcctttat tttttatttc
     3541 ttcatttaaa tcaaaaatat gatttatttt tccattgttc attattccta tcttatgagc
     3601 aaaaaacatt gcttcagaaa tatcatgagt aacatgaatc actgttggtt tgtattttat
     3661 gtagacatcc ttcaaaattt tgcttatatg tttttttgta atataatcca atgaactcat
     3721 aggttcatct aaaagtaata tatcaggttc agctattaag gcacgtgcaa aagcaactcg
     3781 ttgcttttcg cctccactta aatttttagg atacctattt tttatatctt ctatctgcat
     3841 taatttagac aagtggttag ccttaagaat ctgttcatct ataggtattt ttctcaattt
     3901 aagtggaaac cttatattat cttcaacatt catatttgga aataattcaa aattttgata
     3961 tacaaatcct atatttctat tttctggagg taagtttgat attaaatttt ctttgtatga
     4021 tacatttcct ttagcagatg gatatcttcc tgctaatgtt tctagaaata gagttttacc
     4081 tgacccacta gctcctaata aaacaaagta ttcatgatta ttaatattta aactattttc
     4141 ttgtaattta aaattaggta aatcaagaga taaatttttt atttttaaca tattaattct
     4201 tatcaacctc tctattaaaa aatatctcaa aaagcatcaa gcatgtaagt gagagaaata
     4261 tcaaaattac agctattccg atagcaatgt ctatatcacc agtagacata tttaaatata
     4321 tagatgtagg aataatttca gttttcatac gtgtagaacc tgctatcata gctactgcac
     4381 caaattcacc aagtgctctt gaccaagtca ttacagttgc agatatgatt ccagttttta
     4441 gatttggaag aattataaat ctaaatgctt cccaactatt acatccaagg gtacgtgcaa
     4501 caaatatcat cttttcatta ctttcattta atgaagtgtg aagtatttta atagtaagtg
     4561 gaagatttac aaatatttgt gctaaaacta taccttgctt tgtaaatata aaatcaagct
     4621 taaaaatctt ataaatggaa tctccaatcc ccattcttcc aaacaaaagt aaaagagcaa
     4681 ttcctgatac taagtgtgga agagacatag ggagatttat tatctgtata atcagttttt
     4741 taaatggtaa tttagtaata tgtaaaaaat atgctactgg aatagctaat aaaaggcata
     4801 ctatagtaga tattaaagat gttttaatac taagtgttat tgcatactgt acttccactg
     4861 attttaagca tataggaaca taacttatcc ctttaatgat taacataaga agtggtgata
     4921 caataaacaa aaagactata gcaaaaaatc cagtaagtag agtagtaaaa aatttatttt
     4981 tcaagtttaa tcactactta acaggttcaa aaccatattt tttaaatatc tgtttagctt
     5041 cgtctgactc tatataattt ataaatttat tagctaaatc ttttttatca ctatagttta
     5101 cgattcctgc tgatatgagt tggtctatat ttttatcttg ggcaatttct ataacttcta
     5161 catcttcatt accaaagacc gaatcttttg tggctattgt agcatcagct ttacttgatg
     5221 ttaactgtac aatcatttca tttacagttg cagctgtaga gacaacatta tcatttatag
     5281 attttaaatt atttttttca agtatttttt gtgtagtctt acctatagca ttagactctt
     5341 tgtctcccaa aataagttta actccatctt tatttaagtc ttccaatttt tgaatattag
     5401 ctggatttcc tttaggtaca actattgcag gtgtatgatg tgcaaccgtt ttatgttcac
     5461 ctacaagttc tttttcaaag gcctttgaat aaattggttc agaaccaaca ataaatacgt
     5521 ctcctttgtg acttgtctca atttgagcta ttagctgtgc agaacctgca tagctatatt
     5581 caactttgac attattttct ttctcaaatt tttttgctat ttcatccatt ggtttcttta
     5641 aacctgcccc tgaatagaca aaaagagtct ctttttcttt tgaatcatca gctgttgtca
     5701 ctttagtatt agattcatca ttagctttgt tttctttaga attacatgca gtaatactta
     5761 atgaaataat catagctaaa gctagtactg aaagtttttt aaacataaga tattccccct
     5821 tattaaatta gtgtaaattc ttttttagta tatcatacta agaaaacgat gtctaagttt
     5881 ttgttatgtt ttataatgtt ttgttatgtt ttgttatgta tagttaagaa aaaatctatt
     5941 cataatgtca tttccatagg tagttatttt atttttaatt tttattaata ctttaaagta
     6001 ttttaaattt aaaaacttaa atcaaattaa cttattgtag attttttact ttttaactaa
     6061 ttttatattt attatatttc agtgaaaaaa tagaacattg aaacatatag atatgtttta
     6121 attgcttttt attaacaaat tactaaaagt attatatcag aattgaatac aaaagaaaga
     6181 gtatgtattt atgagatagt tgaaaatttt gatgtgccac aactaaaatt attatattac
     6241 tatatattct aattaaaaga gtacttgtag gtttaagtac atactttata aatatatttt
     6301 tgtcagattt attttataaa aagtatttag actaagtatt atttttaagt atttttttgt
     6361 tgaagttatt ttttcctttt ttacaaaatg cgtaaataaa aaaaagactc ttaaaagagt
     6421 ctttccgaaa aatctatata ttataatata gttatatttt ctgcttgagg acctctagcg
     6481 cctttaacta tatcaaagct tactttttga ccttcttcta atgatttaaa tcctgaagtt
     6541 tgtatagctg agaaatgagc aaatacgtca tctccacttt ccattgatat aaatccaaat
     6601 cctttttcat tattaaacca ttttactatt ccattattca ttaaaaatac tcctattaac
     6661 ctatatcaag atatacttga tttacttgtg tattaccaca aatactattg tatcatagat
     6721 taacataaat gtctatttaa ttataatttt tagttaacat ttttatttat tcttaatatg
     6781 aaaataaatt taaacatttt atattaccaa tatattaatg taaatgtaga taaaactaaa
     6841 aagggttttc tagaaaaaaa tctgtctaat tatacttact taccaatacc atcacttgat
     6901 gcaagcaaga ttccacaact ttttctccgt actctaatat aaaatcatct aactgtgtat
     6961 ctataaaatc acaataatca tatgaactac caatataagc agttaacata tgtgtacatt
     7021 tatccatttt atctctaaac ataatgtatt tatcccccta aaaaactttc atgaaaaaca
     7081 aaaagaaaat atctttttgg caactggctg acataactta ttttataagc gttagtccct
     7141 atagctttgc gtcactaaat ttctctagtt ttgccgattt agttttattc tacagattaa
     7201 taatacaata gaattagtta ttattcaaca tatctagctg aaaaattaat aaatttatat
     7261 atgaacgtta aattatctga aaaaataaaa agcccctctg tcaggagtga cttaaaaatt
     7321 gaatttaagt ttgtatttaa aacacatttt taataatgca aaaactaatc aaaaataaac
     7381 aattcatcaa taggtgtatc tactattttt gatatatcta ttgctaattt caaagaagga
     7441 ttatactttc ctgcttctaa acgcataatg gtttctcttc taactcctac tttttctgct
     7501 aattgttctt gagttaattc ttttaattgt ctatattttt ttaggttaca agtgaattta
     7561 ggcatattat ttttcctcta aaatataaag ttttatagca taaacattta aagtgattgc
     7621 atatgtaatt gatagtaaaa cacacattaa ttctatattc ctagacacta tagtaataca
     7681 ccataaaatg aataattcta taatagcaag ctgtcctgta aatgccatag ctgctttttc
     7741 atcttgtaca tacctttcat ctgctttatc accatttatt tttgatataa taaagtttga
     7801 gaaaaaagca aaaaatccaa tatatgtaag gtcagcaaca ttgccagatg aaaaatatct
     7861 aagacttaaa aatccaagga aaccacaaaa acccataaaa aattttttct gaatcatttt
     7921 ttatcctcct tagtaatttt aaaagagata tatttatatc tttatgatac aaatatatct
     7981 cttttatatt cttttgtcaa tagaaaatca gtattataca atatttgtac tgcaccataa
     8041 ttgttagagc aaaaatctac tgcttgagat gtttatgtat gactaaatat gattttaatt
     8101 tcaaattaaa agtagctaaa ttttatttga atagagaagg aagagatatt ttaatagtaa
     8161 aacaatatgg agtttataac cattctcaag ttgaaagatg ggttaatata ttaggagagt
     8221 gtgcactaaa aataaaaaaa attttctata ctatatggtt caagttagat gttataaact
     8281 atatgatgat aactaaatat agtgtacaat aaatcgctaa gtattttgga ataaacaata
     8341 gcacagttat agcaacatga aaataaaaat ttttacatag tggtgttgat gccttttcta
     8401 aaatgaaagg aagaccataa tgaataaaaa caaaaacact aaagaaaaaa taaattaaca
     8461 agagaacaag aattagaata tgaaaataaa tttttaaaag atgagcttga gtttttaaaa
     8521 aagatgtgtg cctcagggaa gccacattaa aaaacagtgg tatcattatt aatcaaaaga
     8581 aagttagatg tattatcaaa aaattagaac ttaaatgcat agcatttttt cataaatcac
     8641 ataaatataa ctcctataaa tgtataattg gaaaagtaaa aaataataaa acaaatagaa
     8701 gatttaaaat atcaatagca tatcagaaaa taacaaatga tatgctagaa tttataaaat
     8761 atatctaatg ataaaaatgg aaaatcaatt ataaaaaagg catatcccga ttcatttttt
     8821 gttatatagt caaataagaa tactatagat gaaagatacg attttgcata tgtattaagt
     8881 aagtattctg atgtttttgg ttgatacaca tgcaataaag aagttgtgtt tgcagataaa
     8941 ttagcaaaac tatagtataa gttgcaacaa taaagaaaat gaaaattatc atactaaagc
     9001 ataaggcatg ttacaatttt attagatagg acattaacat acattaaagt actttttatt
     9061 ataaagagta cttatttttt tgaaattcat taatgtataa actatcaaga atattactca
     9121 acataattta aaaacaactt gaataggtat ttttaaatta tgtgatataa taaaaaatag
     9181 aagtgtatgc caatacactt ctgtaattat aactaagcat tctattcttg aggagtgctt
     9241 ttttcatttc tccaaacaag attgtttatt tcatcagcaa ttattaaata aaatttattg
     9301 tatttaagta ttcgatttat catttaaaaa ttttattaca atatctattt tgttttgctc
     9361 gttcattatg tctattgaac ttccataatc actttttaat ttatctagac cacttttgct
     9421 tatttctcct tctggaagta tacttaattc tagatatttt tcatgaccag gagatgacat
     9481 taatagatat gaaccattat aaggcatacc taaattttct attttatctg ctaatgggtc
     9541 atctttaaag ccaccattta ttattatttt tccatctttc tttacccatg atatcattcc
     9601 tccatcagta tattttgatt catctgcata gtagctaaga gacgcacttt ttattgcact
     9661 tatatcagct tcaagtttag ctatctttgc tttttctata tttttaaata atgctggaag
     9721 tgctactatt gccaatattc ctattatagc aattactact aataattcca ctagagtaaa
     9781 tcctttttta tttttcattt atttcccctc catataaaat taataatata taaattttta
     9841 ttttgttgat ttctactttc tatattttac catatataga caaaaaaatc actttctatg
     9901 acaaatatac tattatttta caatttatgg aaatgattta aaatgacatt tcttgttaga
     9961 aaagatataa gaaatggatt aaaataaaga aaactacagt catatcaatg tcaataatat
    10021 tatttaaaag cagatgaaaa taaaaagagg actcagaaaa taatgtctat ttaattatac
    10081 ttacttacca ataccataac ttgatataaa caagattata ctacattttt tttatgctct
    10141 agtataaaat catctaactg tgtatctata aaatcaaaat aattatatga actatcagta
    10201 taataagtca aaatatgtat acatgaatac atattttaaa agatatatat tattacatac
    10261 ctaaaaaact ttcataaaaa caaaaataaa atatgctttt agtaacttgt taacataact
    10321 tataatttat tttataggca ttagcctata tagctttgtg ctactaaatt tctttgattc
    10381 tagcgattta gtgctattct acaactaaaa taatacaata gagctattta ttgtttggta
    10441 gcattgtttg caaattaaac aaatttatat atatgaatat tattttacgt ttaaaaaaac
    10501 agactaaata tgtagaatat ttggtaaaac ttacctctag tttttgtctt aaaaagctcc
    10561 tattattaat ttaagttaga agaattaagg aagtgacata aattgaaaga agaaatatta
    10621 atagaaaaat tattaagagt agaattaata gtaatggagt atttatggaa aaaagacact
    10681 ctaatgccta aaaaaaaaat tgtaaaagaa ataaaacaga tttatggatg gcataaaagt
    10741 acaataaaaa tactactaaa aaggctagtt gataaaaggt atttggctag atatattata
    10801 aattttcaat cttattataa aataataata gataataaag aatattatac ttttaagaaa
    10861 aaggtactaa aatctagtaa aagcataaaa ataatgcatt cacttaccac tatacataaa
    10921 aatgtaagta aagagaagtt agacctatta gatgagtatt atagaaactt aaaagaatga
    10981 tatagtaaaa atcgaatgta attatttacc ttaattcctt tgtttgtaaa actttattga
    11041 tatagaattt gacatataca taaattggta aagggatgta tactatgaaa attagtaaat
    11101 taccagaagc ggaattaaaa gttatgagat atatttggga atcagaaaag gtattaatac
    11161 caagagaaat caccaagtct atggaacaaa aatatgaatg gaaagataca actatattta
    11221 cagtattaaa aagattacta aagaagagag tttttagaag cggagaaaat a
//
LOCUS       DAEPKC010000112        11260 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.112, whole genome shotgun sequence.
ACCESSION   DAEPKC010000112 DAEPKC010000000
VERSION     DAEPKC010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11260)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11260)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11260
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.112"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            425..2920
                     /locus_tag="KR294_003208"
     CDS             425..2920
                     /locus_tag="KR294_003208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH0241263.1"
                     /translation="MPENNNQLLEEITLLLNEGKVAINKAENQNLILILGGTGCGKST
                     AINYLAGCVMMEVEDEDTGISYIDCLDPVAEIGSGAVSQTLYPNIVNMRKPIEGMDAK
                     LCDTAGFSDNRGVAHDISAAVSLGEVFKNSASICAVIVLIPEADILDSRLTKVLDLFQ
                     QLNMCLHKENFKGSITFFISKSFLGRTEKQIYNVIKRKYEQLCENLDSNIEEKAWLFE
                     ELLKDNGKNIHLCKPLASDEREGLLKQVLELDEVKDKTSAFQYPISADARLVLDTLIK
                     EIQNNIVSSLEDYVKAYTEDFINIIGSITMIQEIAKYDEVVKVFKNWLESTTSLTIER
                     FINVLAKQSGLFLQDSCMKLQNKIKGNLDIIDALSKYTEHGTGEILLPSVHMEFIIEK
                     ASKKIMEQNFIIIRKNLEKVLVSYEVQKQVFTLPNREKLMEVANKKDYVYSVSDFNSI
                     LTNVTVTQNEELEDSITRLSAYGEEGNEIIREFIGKYILNPFIVKTININDKKGIEIR
                     ALIPNLVISSVLEYFKNRKVDDNVSTFMFFAKDTIYMDDNLGMDFASEKNIILASNNL
                     DVGSNVKINVSGKSGELVDNSMYGKNGEDGRDAGNIYLYIKEEIRNYRLTLIANGGNG
                     SKGIDGENGETGASGSNGADAGYTSYFHGQMFKGYFEKGTSGKKGEKGGAGGNAGRGG
                     NAGKKGNIYFISDSEEQKNRIINHCDITVKDGEAGPNGRPGLGGYGGSGGYHGYNTLS
                     FSPSGIDKTVYYTGYFTSWDYKLDSIIKYHIEFSGGSWNEGKTGPAREYAEYGDRGDN
                     GGFNAPNTKLSTAVSKVEENLIKEKYQGYCSEI"
     gene            2935..8145
                     /locus_tag="KR294_003209"
     CDS             2935..8145
                     /locus_tag="KR294_003209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosome-binding GTPase"
                     /protein_id="HBH0241264.1"
                     /translation="MANKLYSEIVNLLEEGRDELRKYDLKEKSILLFLGASGVGKSTC
                     INYLKGCVMEEKTDEETGQIYITAKDSAVEIGNGVYSKTLCPEVVDIANRDFSLCDCP
                     GFFDNRGAEYMIAGAMLVRETISTSSKVKGMVVILDYQSLLDSRHTLLIETGKNLKDM
                     LGDYAKYKENFFFLINKIPKTLIGNVTEEKIRNILEKAKEDLDSQEKDYDGCKELVYL
                     LNVALSDGVSIKLCNPLDKQPEKLLNEMKNLPETFEKTDLGLMLTASCKIEIQKAVDV
                     TYKDLEKLLVPYIESVKKGMEDSISILSSINSLKDKKIQLDKMYTDLCSRTNNMKELM
                     EFVQELSYGDGVQKVNILEETRLLLELNSYCSETHIVGLSELLKSLLKNTLEDTLKDI
                     KYWIAEEEYREEEAKRLEDAEYRIEKIQSCTYIKSYEKENVLSIYIPIPKVNLSDLTK
                     IISGYQLNILSSIYMYGDCELKIDCNMEKEVFSGKNIVLLTEKLHIPEGTYSINVSGK
                     DAEKLVGESSIYDGMNGRNGNNAGTSGDIILSFKEIEKRGELKLYVDGGRGGNGQDGK
                     KGDTGITGEAGANAKIGSKKESKEFANVKGTKYYVVKAEKGKQGGTGGTGGNGGNAGL
                     GSKSGQVYLLGKAPLLKSAISKKDGNHGLAGKGGSGGAGGAGGLGGIRGIYEETIRYI
                     GTSPPMDNSDRNYYYFDRYVFNHALNQKQAADDGEKLNTLYEEHKDWTISKREDSGSA
                     GAEGKAGHSGDALKEKELLKQEYSLSIDTFFYEFFERFGFSGIKGYRNLRLLCAVGIL
                     EADILELSHIYEIFHAVEKIEMQLNREILQKYYSFEKKNKAVLSLDDMNTKKEFYKEA
                     KEIYEYLINKLMQSDRIESFVGKNQNFSEWSMILFALEQKTAFYVQMIEESEIGGNRV
                     TDIRSLTDYLDKTLRELEQGKKDELKEGYFNTYKESILTQIESGNQQIEVLKNELENK
                     MLSVNAKMNLLIQEIIKMKEDEQEDIEELKKKQAKLEEQMKTQLILSGIQSALSLLTA
                     FSGVGQACLGAFDSAKSLKENLSAKEEEYKWTNRMVNFSDFKLDSDGMRFVLGEQLSE
                     DRKNALDKMTYNLAGVDEERRTKFDQIKEIIVKSIDDDNYADKADDIQRAKEGLSESE
                     YKEIYTKIQKKEIGMLEANYNNKQQKDKLAALEKSKQAIERQQKTSKIKNALSIGSSA
                     CSLINTAISGVNNCLNVKSSFESKIEVVKEAIKDKENNIKKLDELNTQMVEFKDKTLK
                     ESVIPFVEKFDSTVKNQDIFENEISKLKMKEVLTELSTKFGSLKMENSEEISIIFKKV
                     QDMMETQIIITDKIDKKKDNLAMGELIYQMSDSGNQMNEYQKKLIHQIELNQVRYLCQ
                     VEAAAFQLWTFPFGSNIVNILNRCHVGITEDENEVINQAKEQNRQIREFLDQDAYQWQ
                     KTDNHILKVALTGSLDGKSRVGFENTYSLYDCNEEEVKKLLTGDEISFEVPLNKNFDA
                     IKYVTMYANIPNLRRNILEDSLKVKVHIHLYDSGYFSLYDDKKDVYYQYVFPQNYINI
                     THGLDIKYNDSDSINSIWSSVEDKGIEKFKNAGLNSGRSPYSMAKISLKAHFNRKLSY
                     DSLTNEQKKKLESYFDKPSKYAWSDSIDILRSLGYIDLKGILSKSWYEIKKDIDSDGE
                     IMKHFSILQVNLLERIIYEQTSILKENIPNLTIELVGCGIYVESEFNYLKQNDLKCYE
                     ERLVENTIIG"
     gene            complement(8370..10469)
                     /locus_tag="KR294_003210"
     CDS             complement(8370..10469)
                     /locus_tag="KR294_003210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HBH0241265.1"
                     /translation="MNFYIKHEIRGRIRFDLQLGKLNNKQSDTLLYYLTSINGITKAK
                     VYDRTGDAVIYYTGEREYIIREITKFSFNNSKIENLVPEHTSRELNNYYRDKLANKLL
                     VKSISKIFFPKSLRFFLIGLHSIKYFKKGLSSLLNKKIEVSVLDATAIGISIFRKDIN
                     TAGSVMFLLGIGELLEEWTRKKSIDDLAQSMSLNIEKVWLRKGDTEILIPISEIKEGD
                     LVSVTMGNMIPLDGVIVSGETMVNQASLTGESLAVNKKEGSYIYAGTVIEQGNIVMCV
                     KEKAGTTRFQKIVTMIEESEKLKSSVESKFEHLADTLVPYSFLGSILTYAITRNPIKS
                     LSILMVDFSCALKLSIPISVLSAMRECNNNNITVKGGKFLEGVACADTIVFDKTGTLT
                     KAQPTVSDIITFQNYNKEDMLRLAACLEEHFPHSIANAVVYEAEKQGLSHKEMHTEVE
                     YIIAHGISTKVDDKKVVIGSKHFVFEDEKCTIPDGEEDKYNNLSDEYSHLFMAISGKL
                     SAVICINDPLRKEAKYVISNLRECGIKKIVMMTGDSEKTAKSIASKVGVDEYYSEVLP
                     EDKANFVKSEKLKGRKVIMIGDGINDSPAISESDVGIAMSEGAEIAREISDITISADN
                     LNNLIVLKQISNKLMKRVDLSSKFIIGFNLGLILLGVGGFVRPSTSAFLHNASTVGIS
                     LNSMTNLLENTNTYNYH"
     gene            complement(10512..10907)
                     /locus_tag="KR294_003211"
     CDS             complement(10512..10907)
                     /locus_tag="KR294_003211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241266.1"
                     /translation="MNILKMKKTGIFLGGVLFGTVGVKILSSDCVKKTCTRATAGALK
                     VKDSVLETTTKIQENVEDILAEAKEINEQEDLSTSKVNVVQDTLKCEQEVLKTETIKT
                     VEDTNSNSIKCEEIKDNVIEEKNSTCTTE"
BASE COUNT         4287 a         1311 c         2052 g         3610 t
ORIGIN      
        1 aaccagtata gttgaactat ttaagcaaat aaaaataaaa tattcaagct ggtataggtg
       61 taaaacttaa gcagtagtat aggaatgttt aaattaatgg tacaaatata attaaaaatc
      121 tatatgtaat aaccacagga aaataatgga catataatat aaaaaacaac tgtattacat
      181 aaaatacaat aaaataagcg cattaaataa aataactgtg ttgataaaga ttatattata
      241 caacacagtt attttaataa acaaagaaga ataattattg agtgaaaata caaatttagt
      301 gaaaatgcaa atttattaaa aataaaaaat aaaaaacaaa tttaaatata gtataaaaac
      361 tttgcaatct acttaaggga ttaaacttta tttaaataaa atatataacc aagggggaaa
      421 ataaatgcca gaaaataaca atcaactttt agaagaaata acactcttat taaatgaagg
      481 aaaagtagca ataaataagg ctgaaaatca aaatttaatt ctaattcttg gtgggacagg
      541 atgtggcaaa agtactgcaa ttaactatct tgcaggatgt gtaatgatgg aagtagaaga
      601 tgaagatact ggtatatcat atattgattg cttagaccct gtggcagaga ttggttcagg
      661 agctgtttct caaactttat acccgaacat tgtaaatatg agaaaaccaa tagaaggaat
      721 ggatgcaaaa ttatgtgata ctgcaggttt tagcgacaat aggggagtag cccatgatat
      781 tagtgcagca gtttcattag gtgaagtatt taaaaattct gcatctatat gtgcagtaat
      841 tgtattgata ccagaagcag atatattaga ttctagactt acaaaagtac tagacctgtt
      901 ccaacagtta aatatgtgtc ttcataaaga aaattttaag ggtagtataa cttttttcat
      961 ttcaaaaagt ttcttaggaa gaacagaaaa acaaatatat aatgttataa aaagaaaata
     1021 tgaacaatta tgcgaaaatt tagacagtaa tatagaggaa aaagcttggt tatttgaaga
     1081 attgctaaaa gataatggaa aaaatattca tctttgtaag ccacttgcat cagatgagag
     1141 ggaaggctta ttaaagcaag tactagaatt agatgaagtt aaagataaga catcagcatt
     1201 ccaatatcca attagtgcag atgcaagatt agttttagat acgttgataa aagaaattca
     1261 aaacaatatc gtatctagcc tagaagatta tgttaaggcg tatacagaag attttatcaa
     1321 tattattgga agtataacaa tgattcaaga aatagcaaaa tatgatgagg ttgtaaaagt
     1381 atttaaaaac tggttggaaa gtacaacaag tcttactata gagagattta tcaacgtatt
     1441 agccaaacaa agtggattat tcttacaaga tagttgcatg aaattacaaa ataagataaa
     1501 aggaaactta gatataattg atgctttaag taaatataca gaacatggaa ctggggaaat
     1561 tttattacct tctgtacata tggaatttat tatagaaaag gcaagtaaga agataatgga
     1621 acaaaacttc attataataa gaaagaattt agaaaaagtt ttagtttctt atgaagtgca
     1681 aaaacaggta tttacattac caaatagaga aaaattaatg gaagttgcaa ataaaaagga
     1741 ttatgtatat agtgtaagtg attttaattc aattttgaca aatgttacag ttacacaaaa
     1801 tgaagagtta gaagacagta taacaagatt aagtgcatat ggagaagaag gtaatgagat
     1861 aattagagaa tttattggta aatacatttt aaatccattt atagtaaaaa caattaatat
     1921 taatgataag aaaggtattg aaataagagc attaattcca aacttagtaa ttagcagtgt
     1981 attggaatat ttcaaaaata gaaaagtaga tgacaatgtt tctacattta tgttctttgc
     2041 taaagatact atttatatgg atgataacct tggaatggac tttgcatcag agaaaaatat
     2101 tattcttgct tctaacaatc ttgatgtagg tagtaatgta aaaattaatg taagtggaaa
     2161 gagcggagaa cttgtagata attctatgta tgggaaaaat ggtgaagatg gtagagatgc
     2221 aggtaatatt tacttatata ttaaagaaga aattagaaat tatcgtctaa cactgattgc
     2281 aaatggagga aatggttcta aaggaataga tggggaaaat ggtgaaacag gagcttctgg
     2341 aagtaatgga gctgatgcag gatatacaag ttatttccac ggacagatgt ttaaagggta
     2401 ttttgaaaaa ggtacaagtg gcaaaaaagg tgaaaaaggt ggagctggtg gaaatgctgg
     2461 aagaggtgga aatgctggta agaaaggtaa tatttacttc atttcagatt cagaggaaca
     2521 aaaaaataga ataattaatc attgtgatat aacagtgaaa gatggagaag caggtccaaa
     2581 tggtagacca ggtttaggtg gatatggagg aagtggtggc tatcacggat ataatacact
     2641 ttcattttct ccaagtggta tagataagac tgtatactat acaggatatt ttacaagttg
     2701 ggattataag ttagatagta taattaaata tcatatagaa tttagtggtg gaagctggaa
     2761 tgaaggtaaa acaggaccag caagagaata cgctgaatat ggagatagag gagacaatgg
     2821 aggatttaat gctccaaata ctaagttatc aacagctgtt tcaaaggtag aagagaatct
     2881 tattaaagaa aaatatcaag gctattgttc cgaaatatag aaagggatgg atgtatggca
     2941 aataaacttt atagtgaaat cgtaaacctt ttggaagaag gaagagacga gcttagaaaa
     3001 tatgacttaa aagaaaagtc aattttgtta ttcctaggtg cttcaggcgt tggaaagagt
     3061 acttgtataa attatttaaa aggctgtgtg atggaagaaa aaacggatga agagactgga
     3121 caaatatata taactgcaaa agattcagct gtcgaaattg gaaatggtgt atattctaag
     3181 actttatgtc cagaagttgt agatattgca aatagagatt tttcattatg tgattgccca
     3241 ggtttttttg acaaccgtgg agcagagtat atgattgctg gtgctatgct tgtaagggaa
     3301 actatttcca catcttcaaa ggtaaaaggg atggtagtta ttttagacta tcaatcccta
     3361 ctggactcta gacatacatt attgatagaa acaggcaaaa atttgaaaga tatgcttggt
     3421 gattatgcaa agtataaaga aaatttcttc tttcttatca ataaaatacc taaaacacta
     3481 attggtaatg taacagaaga aaaaataaga aatatattgg aaaaagcaaa agaagaccta
     3541 gatagtcaag agaaagatta cgacggttgt aaggaattag tgtacttatt aaatgtagca
     3601 ttatcagatg gtgtatctat taaattatgt aatccactag ataaacagcc agaaaagttg
     3661 ttgaatgaaa tgaaaaatct acctgaaaca tttgaaaaaa cagatttggg attgatgctt
     3721 actgcttctt gtaaaataga aatacaaaaa gctgttgatg taacctataa agacctagaa
     3781 aaacttttag ttccttatat agaaagtgtt aaaaaaggta tggaagattc tatttccatt
     3841 ctatcttcta taaatagtct aaaagataaa aagattcaat tagataagat gtatacagat
     3901 ttatgtagta ggactaataa tatgaaagag cttatggagt ttgtacaaga actttcatat
     3961 ggtgatggcg tacagaaagt gaatatatta gaagaaacac gtcttctttt agagttaaat
     4021 agttactgta gtgagactca tattgttggt ctaagtgagt tgttaaaatc attgctaaaa
     4081 aatactttag aagatacatt gaaagatatc aaatattgga tagcagaaga agaatatagg
     4141 gaagaagaag ccaaaaggct tgaagatgca gagtatagga tagagaagat tcaaagttgt
     4201 acatatataa aatcatatga gaaagaaaat gtactttcta tatatattcc tatacctaaa
     4261 gtgaatttat cggatttgac taaaataata tctggttatc aacttaatat tttgtcatct
     4321 atatatatgt atggagattg tgagttgaaa attgactgta atatggagaa agaagtcttc
     4381 tcaggtaaga atattgtact acttacagaa aaattacata taccagaagg gacttattca
     4441 atcaacgtat ctggtaagga tgcagaaaaa ttggttggag aaagttctat ttacgacgga
     4501 atgaatggaa gaaatggcaa taatgcaggt acttcaggtg atatcatatt atcttttaaa
     4561 gaaatagaaa aaagaggaga acttaaactt tacgtagatg gtggacgtgg tggaaatgga
     4621 caagatggaa aaaaaggaga tacagggata actggagaag ctggggcaaa tgctaaaata
     4681 ggttctaaaa aagagtcaaa agaatttgct aatgttaaag gtacaaaata ctatgtggta
     4741 aaagcagaaa aaggaaaaca aggtggaact ggaggcacag gaggtaatgg tggaaatgca
     4801 ggtcttggaa gcaagtctgg acaggtttat ctccttggaa aagctccttt attaaaaagt
     4861 gctataagta aaaaagatgg aaatcatggt ttagcaggaa aaggaggctc tggaggagct
     4921 ggtggtgcag gaggtcttgg tggaattaga ggtatatatg aagaaacaat aagatatata
     4981 ggtacctctc ctccaatgga taatagtgat agaaactact attattttga tagatatgtg
     5041 tttaatcatg ctttaaatca gaagcaagca gcagatgatg gagagaaatt aaatactctt
     5101 tatgaagaac ataaggactg gacaattagc aaacgtgaag attcaggttc agccggagca
     5161 gagggaaaag ccggtcactc tggagatgca ctaaaagaaa aggaattgtt aaagcaggag
     5221 tattctttgt caatagatac attcttctat gaatttttcg agagatttgg tttttctgga
     5281 attaaaggtt atagaaatct tagactgttg tgtgcagtag gaattttaga agctgatatt
     5341 ttagaacttt cacatattta tgaaattttt catgcagttg agaaaataga gatgcaatta
     5401 aatagagaaa tacttcagaa gtactatagt tttgagaaga aaaataaagc agtactttct
     5461 ctggatgata tgaatacaaa gaaagaattt tataaagaag caaaggaaat ctatgaatac
     5521 cttataaata aattgatgca gtctgataga atagaatctt ttgtaggaaa aaatcagaat
     5581 tttagcgaat ggagtatgat tttatttgca cttgagcaga agacagcatt ttatgtgcag
     5641 atgattgaag aaagtgaaat tggaggaaat cgtgttacag atattcgttc tttgacagat
     5701 tatctggata agaccttaag agaattggaa caagggaaga aagatgagtt aaaagaagga
     5761 tatttcaata catataagga aagtatccta actcaaattg aatctggaaa tcaacaaata
     5821 gaggttttaa aaaatgaact tgagaataaa atgctttctg ttaatgcaaa aatgaacctg
     5881 ttgattcaag aaattataaa gatgaaagaa gatgaacaag aagacataga ggaactaaaa
     5941 aagaaacagg caaaacttga ggaacaaatg aaaacacagt taattctttc tggaatacaa
     6001 agcgcattga gtttactgac tgcatttagt ggtgttggtc aagcttgtct aggggcattt
     6061 gacagtgcaa aatctttgaa ggaaaatctt tcagctaaag aagaggaata caaatggact
     6121 aacaggatgg ttaatttttc agattttaaa ttggattctg atggtatgag atttgtactt
     6181 ggagaacagc taagtgaaga tagaaaaaat gctttagata aaatgactta taatttggca
     6241 ggtgttgatg aagaaagaag aactaaattt gaccaaatta aggagattat agttaagtct
     6301 atagatgatg ataattatgc agacaaagct gacgatattc aaagagcaaa agaggggtta
     6361 agtgaaagcg agtataagga aatttacaca aaaatccaga aaaaagaaat aggtatgttg
     6421 gaggcaaatt acaataataa acagcaaaaa gataagttag ctgcactaga gaaaagtaaa
     6481 caagctattg aaagacagca aaagacatct aaaattaaaa atgcattgag tattggaagt
     6541 tctgcttgtt ctcttataaa tactgcgatt agtggtgtta ataattgtct taatgtaaaa
     6601 tctagttttg agagtaaaat agaggtagtt aaagaggcaa ttaaagataa agaaaataat
     6661 attaagaaat tagatgaatt gaatactcaa atggtggaat ttaaagataa aactttgaaa
     6721 gaatctgtta taccatttgt agaaaaattc gatagtacag ttaaaaatca agatattttt
     6781 gaaaatgaga taagtaaatt aaagatgaag gaagttttaa ctgaattaag cacgaagttt
     6841 ggaagcttaa aaatggaaaa ttcagaggag atttctataa tatttaaaaa agtacaggat
     6901 atgatggaaa ctcaaattat cattactgat aagattgata agaaaaaaga taatcttgca
     6961 atgggagaat tgatttatca aatgtcagat agtggtaatc agatgaatga atatcagaaa
     7021 aaacttatcc atcaaattga attaaatcag gttagatatt tgtgtcaggt tgaggcagca
     7081 gcttttcaac tatggacatt cccatttgga agcaatatag taaatatatt aaatagatgc
     7141 catgtaggga ttacagaaga tgaaaacgag gttataaatc aggcgaaaga gcaaaataga
     7201 cagattagag agtttcttga ccaagatgct taccaatggc aaaaaacaga taaccatatt
     7261 ttgaaggtag cattaacagg cagtttagat gggaaatcac gtgtgggatt tgaaaataca
     7321 tattctctat atgattgtaa tgaagaagaa gtgaaaaagc ttttgacagg agatgaaatt
     7381 agttttgaag ttccattaaa taaaaacttt gatgccataa aatatgtaac catgtatgca
     7441 aatatcccga accttagacg aaatatttta gaggatagtt taaaagtaaa ggtgcatatt
     7501 catttatatg atagtggata cttctctcta tatgatgata aaaaagatgt ctattatcaa
     7561 tatgtatttc cacaaaacta tataaatatt acacatggtc ttgatattaa atacaatgat
     7621 tcagattcaa taaactcaat atggtcttca gtagaagata aaggaattga aaagttcaaa
     7681 aatgcaggat taaactctgg tagaagtcca tattctatgg ctaagatttc tttgaaggca
     7741 cattttaata ggaagctttc ttatgattca cttacaaatg agcagaagaa gaaactagaa
     7801 tcatactttg ataaacctag taagtatgca tggagcgata gtatagatat attgaggagt
     7861 ctagggtata ttgatttgaa gggaattttg tcaaagagtt ggtatgaaat caagaaagat
     7921 atagatagtg atggggagat tatgaagcat ttttctatat tacaagttaa tttattggaa
     7981 agaattattt atgagcagac tagtatacta aaggaaaata tacctaattt gacaattgaa
     8041 ttggtaggct gtggtattta tgtagagtct gaatttaatt atctaaagca aaatgattta
     8101 aaatgctatg aagaaagatt ggttgaaaat acaattattg gttgaaaata taattaatat
     8161 ataaatttta aagaaattta caaaagggga tgtttcaaaa tgaaaatttg aatcatctcc
     8221 ttttttgtaa aaaatagaaa taagttgagt ttaaaatttg taaagtatgc tttatataat
     8281 tttgattaga aaaaagctaa ttttaagaca tattcttttt aaaagatgaa ttataaattt
     8341 tttatatcat atgttttatg taatggagat taatggtagt tataagtatt ggtgttttcc
     8401 aataaatttg tcatactgtt taaacttatt ccgacagtag atgcgttgtg taaaaaggca
     8461 gatgtacttg gtctaacaaa tccacctaca ccaagtaaaa tcaaacctaa attaaagccg
     8521 ataataaact tagaacttaa atcaactctt ttcataagct tattactaat ctgctttaaa
     8581 acgattaaat tattcaaatt atctgctgat atggtaatat ctgaaatctc tcttgctatt
     8641 tcagcacctt cactcattgc aattccgaca tctgattctg aaatagcagg agaatcattg
     8701 attccatcac caatcataat tactttgcga cctttgagtt tttcactttt aacaaaattg
     8761 gctttgtctt ctggtaagac ttctgaataa tattcatcaa caccaacttt acttgctata
     8821 gatttagctg ttttttcgct atctccagtc atcatcacaa tcttttttat tccgcattct
     8881 cttaaatttg aaattacata ttttgcttct tttcgtaaag ggtcatttat gcaaataact
     8941 gctgataatt tacctgatat tgccataaat aggtgtgaat actcatctga tagattattg
     9001 tacttatcct cctcaccgtc tgggatagta cacttctcat cttcaaatac aaaatgtttg
     9061 ctacctatta caaccttttt atcatcaact tttgttgaaa tgccatgagc aataatatat
     9121 tctacttctg tatgcatttc tttgtgacta agcccttgtt tttcagcttc ataaactact
     9181 gcatttgcta tggagtgtgg gaagtgttct tctaagcaag ctgcaagtct taacatatcc
     9241 tccttattat aattttggaa tgtaattata tctgaaacag ttggttgagc ttttgttaat
     9301 gtgcctgtct tatcaaatac aatagtatct gcacatgcaa caccttcaag aaattttcca
     9361 ccttttacag taatgttgtt attgttacat tctctcatgg ctgatagtac tgaaataggg
     9421 atagagagtt ttaatgcaca agagaaatct accattaata tagagagtga ttttataggg
     9481 tttctagtaa ttgcataggt taatatactt cctaaaaagc tgtatggaac taatgtatct
     9541 gctagatgtt caaatttact ctctacagaa gattttagtt tttcagattc ctcaatcata
     9601 gttactattt tctggaatct agtagtacca gctttttcct tgacgcacat aacaatattg
     9661 ccttgctcta ttacagttcc agcatatatg taagagcctt cttttttgtt aactgcaagg
     9721 gattcacctg taagtgatgc ctgattgacc attgtttctc ctgatactat aactccatcc
     9781 aatggaatca tatttcccat agttacactt actaaatctc cttcctttat ctctgaaatt
     9841 ggaattaaga tttcagtgtc accttttctt aaccatactt tttcaatgtt tagtgacata
     9901 ctttgagcca agtcgtctat agattttttt ctagtccatt cttctaatag ttcaccgata
     9961 ccaagaagaa acataactga accagccgta ttgatatctt ttctaaaaat agaaatacct
    10021 atagcagtgg catctaaaac agaaacttct atttttttat ttagcaggga agagagacct
    10081 tttttaaaat attttataga atgaagtcca attaaaaaaa atcttaagga ctttggaaaa
    10141 aatattttgg agatactttt gactagcagt ttatttgcta atttgtctct ataataattg
    10201 tttaattccc tgctggtatg ttcaggaact aggttttcta ttttgctatt gttaaaactg
    10261 aatttagtga tttctcttat tatgtattct ctttcaccag tgtaataaat gactgcatca
    10321 ccagttctat cgtaaacttt tgctttggta ataccattta tagaagttaa ataatataag
    10381 agagtatcgg actgcttgtt gtttaatttg ccaagttgta agtcaaagcg tatacgacct
    10441 cttatttcgt gttttatata aaaattcaat ttacttcctc ctgatattat taatcataat
    10501 aatcattaaa tttattctgt tgtacaagta ctattttttt cttcaattac gttatctttg
    10561 atttcttcac atttaatgct attagaatta gtatcttcta cagtttttat agtttcagtt
    10621 ttaagaactt cttgttcgca tttaagagta tcttgtacaa cgtttacctt agatgtagat
    10681 aagtcttctt gctcgttgat ttcttttgct tcagctaaaa tatcttctac attttcttga
    10741 attttcgtag ttgtttcaag aacagaatct ttaactttca atgctcctgc tgttgcacga
    10801 gtgcaagttt ttttaacaca atcacttgaa agtatcttaa cacctacagt accaaaaagt
    10861 actcctccta aaaatatccc tgtttttttc atttttaaaa tattcatttt acattatcct
    10921 ttcatttagt tagattttgt ttgtacttat gtataaggta acaaatgtta aaaatagagt
    10981 atgttttaca aaattagttt agagagttta gtaattttat ttgatttata ttagtaaatt
    11041 tacatgaatt ttacatgtgt agtttatatg gttgaaataa ttcttatata gcttatatat
    11101 gcagtttata tatctagttt atatatctag cttatgtatg taatttatat atgtagttta
    11161 tatagttgaa ataattctta tctagcttat ataagcaatt tatatatcta gcttatatag
    11221 ttgaggtaat actttatcta gcttatataa tttatataaa
//
LOCUS       DAEPKC010000113        11241 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.113, whole genome shotgun sequence.
ACCESSION   DAEPKC010000113 DAEPKC010000000
VERSION     DAEPKC010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11241)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11241)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11241
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.113"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            275..1108
                     /locus_tag="KR294_003212"
     CDS             275..1108
                     /locus_tag="KR294_003212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0241267.1"
                     /translation="MLKKESIHFINKNRSLIVCEDNFVYLLPCIQLRNWISNFTISFP
                     NQTIISDNYTIIPHGSVTLVFFYDATGLHSLLFGPTTKPKTVGNIANRCDVILIIEFQ
                     PAGFFPLIGIQQSELIDKVVPFSIINTSLDLEIKKIFNESLSIDKLILKLEELLISNI
                     KIEYSYEFILAIQLIIQNSGNISSQEISKKVFYSSRHLNRLFNQYLGLSMKSFSRLVR
                     INKSIKLLNNNKTSLMSICNELGFYDIPHFIKDFKIVCGITPQKYRANMSDFYSEIAK
                     F"
     gene            1146..1607
                     /locus_tag="KR294_003213"
     CDS             1146..1607
                     /locus_tag="KR294_003213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase/bleomycin resistance/dioxygenase
                     family protein"
                     /protein_id="HBH0241268.1"
                     /translation="MKFGGVLLIVKDINKSKKFYEDVMEQKITLDLGEHVSFENGFGL
                     QSNYKAIIGYDLPIYQQSNNFQLYFEVNDIKQWESKINRIGNIEFLHYIKEYPWGQRT
                     FRFYDFDKNIIEISESMESVIKRLLKQGLALEEISKRTMYPVEFITQFQQL"
     gene            1638..1886
                     /locus_tag="KR294_003214"
     CDS             1638..1886
                     /locus_tag="KR294_003214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBH0241269.1"
                     /translation="MQKTKAWGIIEPEKPESQQQMAHMDFAVNDLEEAVQYAIHCGAT
                     IAEEQFTDDWRVMIDPAGHPFCLCQMKSIMESSHFSLL"
     gene            2339..2659
                     /locus_tag="KR294_003215"
     CDS             2339..2659
                     /locus_tag="KR294_003215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein HesB"
                     /protein_id="HBH0241270.1"
                     /translation="MKITLPETAIDTLKSILKDNQDKPNNIRVYFAGVGCGGPSFGLA
                     LDEKKEDDLTYEVGELQFVMSSDEYSQYGDIIIEDTGFGFRVIPENMKDQGGGGCSGC
                     SGCH"
     gene            2797..3441
                     /gene="trmB"
                     /locus_tag="KR294_003216"
     CDS             2797..3441
                     /gene="trmB"
                     /locus_tag="KR294_003216"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HBH0241271.1"
                     /translation="MRRRRKKGADEKLLSYTKYVLRDDIDKLKGKWNLKFRNDNPIHV
                     EFGTGKGKFITTLAKQNPDINYIAMELKEEVLLKAVEKADASNLNNILFLWGDVSNIL
                     DYFEAKELSRIYINFCDPWPKNRWSKRRLTHSGFLEMYNRVLEDDGEIHFKTDNEKLF
                     EFSLNEIAANNWLLKNISLDLGNSEYENNVTTEYEDKFMSQGMRIFRCEAKKRN"
     gene            3570..4316
                     /locus_tag="KR294_003217"
     CDS             3570..4316
                     /locus_tag="KR294_003217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241272.1"
                     /translation="MWEGTMNLANLIPFIISAAALSPINSNDKVLSENQLKDIFPDAN
                     LRAVVKRYINPDEMTISNIKALDGEFYATGESISNLKGISYLENVDNFIFWNNNIKEI
                     PKEALSLKDMDSINLANNYLIDDDVVNSLSHNGVDVNCDLNFIDTKDNQYKLDSKYHN
                     VDIAKGESIDLRKIITKKIDSYYKYWEVTDNLPKDLNFIVSVSDKSVLSCEDMIIKGN
                     KTGQAVVKVILSDKNDLNTSQEVLITVNVK"
     gene            complement(4445..4723)
                     /locus_tag="KR294_003218"
     CDS             complement(4445..4723)
                     /locus_tag="KR294_003218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241273.1"
                     /translation="MVDTLEFGLKILFFILSIIWMGKIMILRTDKQIVINPLLIGISA
                     VLVMLHTSQSNIEFFGLDVQYIRIVLYIIYSLIILIGIWATNRRNGIF"
     gene            4998..5444
                     /locus_tag="KR294_003219"
     CDS             4998..5444
                     /locus_tag="KR294_003219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241274.1"
                     /translation="MESKFFNWYTQSLGGTFGIISCICAYLNGYMFVYTNSASKYFES
                     IGFLGIISSYTLLPLCMLTLIFGVIYSYTPETSDKSIFNIPFFTLNKRLILITVVFGF
                     IGARVYFIIPAILITFNLYSNVLIAKLKYILCKNKENDTNLKESEV"
     gene            5714..6166
                     /gene="accB"
                     /locus_tag="KR294_003220"
     CDS             5714..6166
                     /gene="accB"
                     /locus_tag="KR294_003220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HBH0241275.1"
                     /translation="MNINEIKELLKAIDSTNLEYVKLESSDLRLEVSKKAQSTSSPVL
                     SVQQESVVDLSLEKPVVNDTPVTSNENLSVVVAPLMGTFYDSPSPDADSFVKVGDVVE
                     EGDTLCILEAMKLMNEITSEIKGEIIEVLVSNEELVEYNQPLFKIKPL"
     gene            6182..7543
                     /gene="accC"
                     /locus_tag="KR294_003221"
     CDS             6182..7543
                     /gene="accC"
                     /locus_tag="KR294_003221"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HBH0241276.1"
                     /translation="MIKKILVANRGDIAVRIIRTCKELGIKTVAIYSEIDKDCFHRYI
                     ADESICIGPNNISKSYNNIENIIYLALKLKCDAIHPGFGFLSENPEFAKQCEDNNIIF
                     IGPTREQMILMGDKSRARETMMELNIPVVPGSESVLKTKEEALEVAREIGYPVMIKAS
                     SGGGGKGMRIVRKEEELFSNFDMASSEALAAFSNSDLYMEKFIENPRHIEVQVFGDKH
                     SNAIHLGDRDCSMQRRNQKVIEESLSPYLSDEERQKLHKIAVDIVKGVGYIGAGTIEF
                     IVDKDKNFYFIEMNTRIQVEHPVTEMVTNLDLIKLQISIANGDKIPFKQEDITFRGHA
                     IECRINAEDSSKNFAPSPGKIESLNLPGGFGVRFDTFVYAGYTIPPLYDSMIGKLICW
                     AETREECISRIYRALDEIIVEGINTNVEFQKALVTSEEFREDTHHTKFIEDVFMKKEF
                     ATL"
     gene            7558..8412
                     /locus_tag="KR294_003222"
     CDS             7558..8412
                     /locus_tag="KR294_003222"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HBH0241277.1"
                     /translation="MIKKFLSSKESKYVTISLDDNFKKNSVDDKFWTYCKGCDSHVFR
                     KDIEENSFVCPKCSRHYGLRARKRINLLIDKGTFMEFNSDVEFQNPLNFPKYKEKVDS
                     YKEKTKESEAVVTGYGRINGIKTVICVMNPDFMMGSMGSIVGEKITYSIEYAAENNLP
                     IIICSASGGARMQEGMVSLMQMAKTSQALSKLEEKLLPYISVLTDPTTGGVTASFAML
                     GDIIISEPNTLIGFAGPRVIEQTINQKLPEGFQTSEFLLEKGFIDMIVDRRKMKEVLY
                     QILAMHKK"
     gene            8433..9377
                     /locus_tag="KR294_003223"
     CDS             8433..9377
                     /locus_tag="KR294_003223"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit alpha"
                     /protein_id="HBH0241278.1"
                     /translation="MIENNSEKIKVLENDIKQLITISKANNIDLSDKINSLNEKLEKL
                     KEDAFSHLSAYEKVTLSRDIKRPTTLEYIEHICSNFLELHGDRLFKDDPSMVGGIGQI
                     GKFNVTIVGHQKGRDTKENIKRNFGMPHPEGYRKALRLMKQAEKFNRPIITFIDTSGA
                     FCGLEAEERGQGEAIARNLLEMSKLSVPVITFVIGEGGSGGALGIGVGNDVCMLEHSV
                     YSVISPEGLSSILFKDSSKAKEACDVMKLTSNDLYDLKIIDKIIKEPLGGAQKDVEAV
                     SKEIKAYILERLNHYKDMDKEEIIAQRYKKFRNIGKCL"
     gene            9566..9826
                     /locus_tag="KR294_003224"
     CDS             9566..9826
                     /locus_tag="KR294_003224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003866776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein S"
                     /protein_id="HBH0241279.1"
                     /translation="MEVLKVSSKSNPNSVAGALAGVLRERGVAEIQAIGAGALNQAIK
                     SIAIARGFVAPSGMDLVCIPAFTDIEIEGDKKTAIKLIIEPR"
     gene            9979..10350
                     /locus_tag="KR294_003225"
     CDS             9979..10350
                     /locus_tag="KR294_003225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HBH0241280.1"
                     /translation="MKLKLLVEEYAVCRLNNDSKIPTWIDTEKFYSITRTDDELSVVC
                     LNNNIPSDVKSEKEWRILKILGPLDFSLVGILSKLSSLLADNKISIFAISTYDTDYIL
                     VKEKDIENACKILSCNGYEVE"
     gene            10380..11225
                     /locus_tag="KR294_003226"
     CDS             10380..11225
                     /locus_tag="KR294_003226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241281.1"
                     /translation="MIYIIEILKISVINIFCFIGIFIVFGLIFSITENLNNKFIFSSF
                     GKTGIIVTGAIGTFVHELSHLIMCLIFMHKINSVKFFRPIESKNDGILGYVSHSYKKD
                     NLYQSIGNFFIGIAPIIGGTIMIILIFKILLPDSYMKVTQNIDLKLYVSMINNLNING
                     FIHIILGDISNFIRIMLLTPSVYSLKYFIFMFLMYSISTHMSLSSADLKNSLNGLSFI
                     VIVIFVISSITYLFGFDNLNISSLIVKYNIFISFFMAIGFIFSIVTLIISYILSLVSP
                     FKNFS"
BASE COUNT         4366 a         1176 c         1836 g         3863 t
ORIGIN      
        1 aggactaatt attgtatttg agataagcat ttttaattat ataaattaga catatgtaaa
       61 gtggatataa gttaaatact ataaatgtgc tataatatta aaataacaga taaaagtact
      121 atatttttta ttgattattt taattttatt tgtttattaa atatctaatg agtattcata
      181 ctatctctat tattaaaagc agttaatgat atatagagat aatatggatt cttcttactt
      241 taataaatat tcacgatagg acaggatata atatatgtta aaaaaagaaa gtattcattt
      301 tataaataaa aataggtcac ttatagtttg tgaagacaat tttgtttatc tcttgccttg
      361 tatacaatta agaaattgga tatcgaattt tactatatcg tttccaaatc aaacaataat
      421 ttctgataat tacacgatta ttcctcatgg aagtgtaact ttggtgtttt tttatgatgc
      481 cacagggtta catagtctat tatttggtcc aactactaaa ccaaaaacag taggaaatat
      541 tgctaataga tgtgatgtta tactaattat agaatttcaa cctgctggtt ttttcccgct
      601 tataggtata cagcaaagtg aacttattga taaagttgtt ccattttcta taattaatac
      661 ttcattagat ttagaaatta aaaaaatatt taatgaatct ttatctatag ataaattgat
      721 tttaaagttg gaagaattat tgatttctaa tattaaaatt gaatactcat atgagtttat
      781 tttggcaatt cagttgatta ttcaaaactc tggaaatata tcttcacaag aaatttctaa
      841 aaaagtattt tatagttcta ggcatttaaa cagactcttt aatcagtacc tagggttgag
      901 tatgaagtca ttttctcgtt tggtacgtat taataaatct ataaaacttc taaacaataa
      961 taaaacttca ttgatgtcta tatgtaatga attaggattc tatgatatac cacattttat
     1021 taaagatttt aaaattgtct gtggaataac tcctcaaaaa taccgagcta atatgtctga
     1081 tttttacagt gaaattgcaa aattttaagt tataatactt ataacaaaga aaggatagtg
     1141 ataagatgaa atttggagga gtattgctaa ttgtcaaaga cataaataaa tcaaaaaagt
     1201 tttatgaaga tgttatggag caaaaaatca cattagattt aggagaacat gtatcatttg
     1261 aaaatggatt tggattacaa agtaattata aagctataat tggatatgat ttaccaatat
     1321 atcaacaatc aaataacttt cagttgtatt ttgaggttaa tgacatcaaa caatgggaaa
     1381 gtaagataaa tagaatagga aatattgaat ttttgcatta tataaaagaa tacccatggg
     1441 gtcaaagaac ttttaggttt tatgattttg ataaaaatat tatagaaatt tcagaaagta
     1501 tggaaagcgt cataaagagg cttttaaaac aaggtttagc tttagaagaa atttcaaaac
     1561 gcactatgta tccagttgaa tttattacac aatttcaaca attataaaat attaaaatat
     1621 ataatttttt ctttatattg caaaaaacaa aggcttgggg cataatagaa ccagaaaaac
     1681 ctgaatctca acagcaaatg gctcatatgg atttcgctgt taatgattta gaagaagcag
     1741 ttcaatatgc aattcattgt ggagctacaa tcgcagagga gcaatttact gatgactgga
     1801 gagttatgat tgacccagct ggacaccctt tttgcttatg tcagatgaaa tcaattatgg
     1861 aaagtagcca tttttcattg ttatagacca aaatattgtt tattaattac aaaaaagcac
     1921 aacagtatat accgttgtgc ttttacttat tatacatgaa tacactaaaa aatataaata
     1981 gtagagcttt atcaataatg ataattttta aaaaatagta tttttttatt gaataatttc
     2041 ttagatattt taaagtatat aaattttgca tatatgaatt ggacattatc aaatgtgtta
     2101 taatattaaa acaacaaata aaattattat attttttaga ataataattt tatttgttta
     2161 ctaagtttat gatagggtat ttatttaagg taataaaata ttatataaaa tattttaaag
     2221 ccttaggtaa tattaggtag aagttttagt aaaatatgca aaaactaatt gattatgtac
     2281 cttgtatggg tatataatag atattgtttt aataaaatat ttgaaaggga atgatttgat
     2341 gaaaattact ttaccagaaa cagctattga tactttaaaa agtatcttaa aagacaatca
     2401 agataaacct aataatataa gagtatactt tgcaggtgtt ggttgtggag gtccttcttt
     2461 tggattagct ttagatgaga aaaaagaaga tgacttaact tatgaagttg gagaattaca
     2521 atttgtaatg agctctgatg aatatagtca gtatggagat ataataatag aagatacagg
     2581 atttggattt agagttattc ctgaaaatat gaaagatcaa ggtggaggag gatgctctgg
     2641 ttgttcaggg tgccactaag attaagtttt tagtaagttt agaactctct ttatagaaat
     2701 aaatttctat tttaagagag ttctttttat tttttggtga gataatgtat aataaaaatg
     2761 tattttacta attttttata tgtaaggaga attattgtga gaagaagacg aaaaaaaggt
     2821 gcagatgaaa agcttttaag ttatacaaaa tatgttttaa gagacgatat agacaaatta
     2881 aaaggcaagt ggaatttaaa gtttagaaat gataatccaa tacatgttga atttgggact
     2941 ggaaaaggta agtttataac aactttagct aagcagaacc ctgacataaa ttatattgcc
     3001 atggaactta aggaagaagt tcttttaaag gctgttgaaa aagcagatgc ttctaatttg
     3061 aataatatac tatttttatg gggagatgta agcaatattt tggattactt tgaagctaaa
     3121 gaattatcga gaatttatat aaatttctgt gacccatggc ctaaaaatag atggagtaaa
     3181 agaagactca ctcattctgg atttttagaa atgtacaata gggttttgga agatgatggc
     3241 gaaattcact ttaaaacaga taatgaaaaa ttattcgagt ttagtttaaa tgaaattgct
     3301 gcaaataatt ggctattaaa gaatatttct cttgatttag gaaatagtga gtatgaaaat
     3361 aatgttacaa cagagtatga agacaaattt atgtcacaag gtatgcgaat atttagatgt
     3421 gaagctaaaa aacgtaacta gtaatatgtt tataagttta atagtagaaa tttattttaa
     3481 tttatattaa taaagtgtac gaaagtaggt atatataaca aggaaacaga accctctcat
     3541 agaaattaaa ttattataat aaaaaattta tgtgggaggg tactatgaat ttagctaatt
     3601 taataccatt tattatttct gcagcagctt taagtccaat aaattcaaat gataaggttt
     3661 tgagcgaaaa tcaacttaaa gatatttttc ctgatgcaaa tttaagagca gttgtaaaaa
     3721 gatatataaa tccagatgag atgactataa gcaatataaa ggctttagat ggagaatttt
     3781 atgcaactgg tgagagcatt tcaaatttaa aaggtatatc atatcttgaa aatgtagaca
     3841 attttatttt ttggaataat aatataaaag agattcctaa ggaagcttta agtctaaaag
     3901 atatggattc aataaatctt gccaataatt atttgattga tgacgatgta gtaaattctc
     3961 tttctcataa tggtgtggat gtaaattgcg atttaaattt tattgataca aaagataatc
     4021 agtataaact ggactctaaa tatcataacg ttgatatagc aaaaggtgaa agtattgatt
     4081 tgagaaaaat aattacgaag aaaattgata gttattataa atactgggaa gttactgata
     4141 accttccaaa agatttaaat tttattgtat ctgtaagtga taagagtgta ctttcatgtg
     4201 aagatatgat aattaaaggt aataaaacag gtcaagcagt ggtaaaagtt atactaagcg
     4261 acaaaaatga tttaaataca tctcaagaag ttctaattac tgtcaatgta aaataatctg
     4321 tcaacttatt caatcattct attttcaatt taagtgtata atcaaaataa aggttgttag
     4381 taacagaacg ctaatattag tgctttgtta ctagcaacct ttaaatttta tagaaataga
     4441 ttatctaaaa aattccattt cttctgttag tagcccatat tcctattaaa attatcagtg
     4501 aatatattat atacaaaact attcttatat attggacatc taatccaaaa aattcaatgt
     4561 tactctgtga ggtatgcaac atcacaagga ctgcagatat accaataagc aaaggattga
     4621 ttactatttg cttatcagtt cttaaaatca ttattttacc catccaaatt attgataata
     4681 taaaaaataa aattttaaga ccaaattcta atgtatctac caaagcgaaa acatcccttc
     4741 atttataata aatttttcag ctcaacaaaa tataaaaccc tacaaacaac ttttgaatcc
     4801 ataataagat aacttgatta agcactatga aataagtact ataaaacttc atctacatta
     4861 atatatacta cactatactt caaatttctt aaacataaat taatgaaatt aacaaaattt
     4921 tattcagaaa catataaaga tatattttac tatttaaatg catatcatta tatatacagt
     4981 tttaggaggt gaggtatatg gaatctaaat tttttaattg gtacactcaa tccttagggg
     5041 gaacttttgg cattatatca tgtatatgcg catatttaaa tggatacatg tttgtttata
     5101 caaatagtgc tagcaaatat tttgaaagta taggatttct gggaataatt tcaagttata
     5161 cactacttcc actttgtatg cttactttga tttttggagt tatatattct tatactccag
     5221 aaacatccga caaaagtatt tttaatatac ctttttttac tttaaataaa agattaatac
     5281 ttattacagt agtttttggt tttataggtg ctagagttta ctttataatt cctgcaattc
     5341 taataacttt taacctatat agcaatgttt tgatagctaa attaaagtac atcctatgta
     5401 aaaataaaga aaatgatact aatttgaaag aaagcgaagt ctaaattgca taatattggt
     5461 atttgtctta aaaattcccg aggtattaat ttgtattctc ttgtattttg caaaaaatat
     5521 tgaattttat tcattttata cttataattt atattaataa tggaaaatta aaacaaatat
     5581 aagttactgg ttgttaattt aaaattaaaa gatatattga tgtgttgatt ctctagtcag
     5641 cactttttct tttataaatt tgttttttgt gatataatat tagcaccagg taataataca
     5701 agggggtaac aaaatgaaca tcaatgaaat taaggaatta ttaaaggcca tagactcaac
     5761 taacttagaa tatgtaaaac ttgaaagtag cgatttaaga ttagaagtat ctaaaaaagc
     5821 tcaatctaca agttcacctg ttttaagtgt acaacaagaa tcagtagtgg atctttcttt
     5881 agaaaagcca gttgtaaacg atacacctgt cacatctaat gagaatctat cagtagtagt
     5941 agctcctttg atgggaacat tctatgattc tccaagtcca gatgcagata gctttgttaa
     6001 agttggcgat gtagttgaag aaggcgacac tttatgtata ttagaagcaa tgaagcttat
     6061 gaatgagata acaagtgaaa ttaaaggtga aataattgaa gtattagtta gtaatgaaga
     6121 actagtagaa tataatcaac ctttatttaa gataaaacca ttgtagtagg aggtatttaa
     6181 gttgataaaa aaaatactag ttgcaaatag aggcgatata gcagttagaa tcatcagaac
     6241 atgtaaagaa ctaggtataa aaactgttgc tatctattct gaaatagata aagattgttt
     6301 tcatagatat atagctgatg aatctatttg tataggacca aataatataa gtaagagtta
     6361 taataatata gaaaatataa tctatcttgc tcttaaatta aagtgtgatg ctattcatcc
     6421 aggctttgga tttttatcag agaatcctga atttgcaaag caatgtgaag ataataatat
     6481 tatttttata ggtccaacaa gagaacaaat gattttgatg ggagataaat ctagagcaag
     6541 agaaactatg atggaattga atatccctgt tgttcctggt tcagaatctg ttttgaaaac
     6601 taaggaagaa gctttagaag ttgcaagaga aattggatat cctgttatga taaaagcctc
     6661 aagtggaggc ggtggaaaag gtatgagaat cgttagaaaa gaagaagaac ttttttcaaa
     6721 ttttgatatg gcaagttcag aagctctagc agcattttct aatagtgatt tatatatgga
     6781 aaagtttata gaaaatccta gacatataga agtacaagta tttggagata aacattcaaa
     6841 tgcaatacat ttaggtgata gagattgttc tatgcaaagg cgaaatcaaa aagtaataga
     6901 agaatcttta agtccatacc tttcagatga agaaagacaa aaacttcata aaattgcagt
     6961 agatatagta aaaggagtag gttatatcgg tgcaggtact attgagttta tagttgacaa
     7021 agataaaaac ttttatttta tagagatgaa tacaagaata caagttgaac atccagttac
     7081 agagatggta acaaatcttg accttataaa acttcaaata tctatagcta atggggataa
     7141 aattcctttt aaacaagaag atattacttt tagaggtcat gctattgaat gtagaataaa
     7201 tgcagaagat tcatcaaaga attttgctcc atcaccaggt aagatagaat cattaaattt
     7261 acctggaggt tttggtgtta gatttgatac ttttgtatat gcaggatata ctataccacc
     7321 tttatatgat tctatgatag gtaagttaat atgttgggct gaaactagag aagaatgtat
     7381 aagtagaata tatagagctc tagacgaaat tattgtagaa ggtattaata caaatgtaga
     7441 atttcaaaag gcacttgtaa caagtgagga gtttagagaa gatactcatc ataccaaatt
     7501 tatagaagat gtctttatga agaaagaatt tgctacatta taaggagtaa atagattatg
     7561 ataaaaaaat ttttatcatc aaaagaatct aagtatgtta cgatttcttt agatgacaac
     7621 tttaaaaaga atagtgtaga tgataaattt tggacctatt gcaaaggttg tgatagtcat
     7681 gtatttagaa aggacataga agaaaattca tttgtatgtc caaaatgttc aagacattat
     7741 ggcttaagag caagaaaaag aataaattta ttgattgata aaggaacttt tatggagttt
     7801 aattctgatg tagaatttca aaatccacta aattttccta aatacaaaga aaaagtagac
     7861 tcttataagg aaaaaacaaa agagtcagaa gctgttgtca caggttatgg aagaataaat
     7921 ggaattaaaa cagttatttg tgtaatgaat cctgatttta tgatgggaag tatgggttct
     7981 attgttgggg aaaaaataac ttattcaata gagtatgctg ctgaaaataa tttacctata
     8041 attatttgtt ctgcttcagg aggagctaga atgcaagaag gtatggtatc tcttatgcag
     8101 atggcaaaga cttctcaagc actttctaag cttgaagaaa aattattgcc atatatatca
     8161 gttctaactg accctactac tggaggagta actgctagtt ttgctatgct tggtgatatt
     8221 ataatttctg agccaaatac gttgataggt tttgcaggtc caagagtaat agagcaaaca
     8281 ataaatcaaa aacttcctga aggatttcaa acttctgagt ttttacttga aaaaggtttt
     8341 attgacatga tagtagatag aagaaaaatg aaggaagtat tatatcaaat tcttgctatg
     8401 cacaagaaat agggcataaa ggaggaactg ttttgattga aaataatagt gaaaaaataa
     8461 aagtcttaga aaatgatatt aaacaattaa taactatttc taaggcaaat aatatagatt
     8521 taagtgataa aataaattca cttaatgaga aattggaaaa gcttaaggaa gatgcttttt
     8581 cacatctatc agcatatgaa aaggtaacat taagtagaga tataaagaga cctacgacat
     8641 tggaatacat agaacatatt tgttctaatt ttttagaact tcatggagat aggcttttta
     8701 aagatgaccc ttctatggtt ggaggaattg gtcagatagg aaagtttaat gttactatag
     8761 ttggacacca aaaaggaaga gatacaaaag aaaatataaa aagaaatttt ggaatgcctc
     8821 atccagaagg atacagaaaa gcattaagac ttatgaaaca agctgaaaaa tttaatagac
     8881 ctataataac gtttattgat acatcaggag ctttttgtgg tctagaagca gaagaaagag
     8941 gacaaggaga agctattgca agaaacttac ttgaaatgag taaactttct gttccagtaa
     9001 tcacttttgt aattggtgaa ggtggtagtg gaggagcttt aggtatcgga gtaggaaatg
     9061 atgtatgtat gttagaacat tcagtttatt ctgtaatttc tccagaagga ctttctagta
     9121 ttctatttaa agattcatct aaagctaaag aagcttgtga tgttatgaag cttacaagta
     9181 atgatttata tgatttaaaa ataatagata agattataaa agaacctctt ggaggagcac
     9241 aaaaagatgt agaagctgtt tcaaaagaaa taaaagctta tattttagaa agattaaatc
     9301 attacaaaga tatggataaa gaggaaatta tagctcaaag atataaaaaa tttagaaata
     9361 ttggaaaatg cttatagaat ataaagaaat ttgtagtttt ttcataataa aatggttaaa
     9421 aaaaataaag gttttcttaa aacgattata gaagtatatt tttataaaag tatactttaa
     9481 atgatgattg taattagtaa atggcaatta tgatttagta ctttaggtaa tggatacttt
     9541 aacaaattaa caaggagatg ttgaaatgga ggtactaaaa gtttcatcaa aatctaatcc
     9601 taattctgta gctggagcct tggctggagt actaagagaa cgaggcgttg cagaaataca
     9661 agctatagga gctggagctc taaatcaagc gataaaatca attgcaatag caagaggttt
     9721 tgttgcacct agtggaatgg atttagtttg cattcccgca tttactgata tagaaatcga
     9781 aggtgataag aaaacagcca ttaaacttat aattgaacct agataatata tctctttatt
     9841 agaatttaat taagttttaa aggttggcta tagaaatagg acactatagt gaaccttttt
     9901 tactttatat gttttatttt atgtaacttt taatgtataa tcttaagtaa acaaataaga
     9961 ttggaggaaa tatacattat gaaattaaaa ttattggtag aagagtatgc agtatgtaga
    10021 ttaaataatg acagtaaaat accaacatgg atagatacag agaagtttta ctctataact
    10081 agaactgatg atgaattaag tgttgtatgt ttaaataata atattccttc tgatgtcaag
    10141 tcagaaaagg agtggagaat acttaagata ctaggtcctt tagacttttc acttgtagga
    10201 attttatcta agttaagtag tttgttagca gacaacaaaa taagcatatt tgcaatttct
    10261 acttatgata cagactatat cttagtaaaa gaaaaagata tagaaaatgc ttgtaaaatt
    10321 ttaagctgta atggatatga agtagagtag ttaaatactt ttacatgagg acttaactta
    10381 tgatttatat aatcgaaatt ttaaaaataa gtgtaataaa tattttttgt ttcataggaa
    10441 tatttattgt atttggattg atttttagca ttacagaaaa tctaaataat aaatttatat
    10501 tttcatcttt tggaaaaact ggaattattg taactggagc tataggaacg tttgttcatg
    10561 aattgagtca tttgataatg tgtttaattt tcatgcataa aataaattca gttaagtttt
    10621 tcagaccaat agaaagtaaa aatgatggta tactaggata tgtaagtcat agctataaaa
    10681 aagataatct ttatcaaagt ataggaaatt tctttatagg aattgcacct attataggtg
    10741 gaacaataat gattatttta atttttaaga tattactgcc agatagttat atgaaagtga
    10801 ctcaaaatat agatttaaag ttatatgtaa gtatgattaa taatttaaat ataaatgggt
    10861 ttatacacat tattttaggt gatatttcca attttataag aataatgttg ttaacaccta
    10921 gtgtatattc attgaagtat tttatattta tgtttttaat gtattctata tctacacata
    10981 tgtcacttag tagtgctgat ttaaaaaata gcttaaatgg tctgagcttt atagttatag
    11041 ttatttttgt aataagttca attacatact tatttggatt tgataacttg aatatatcca
    11101 gtttaatagt taagtataac atatttataa gtttctttat ggcaataggg tttatttttt
    11161 caatagtaac tctcataata tcctatattt taagcttagt cagcccattt aaaaacttta
    11221 gttaaataaa tacatatttt a
//
LOCUS       DAEPKC010000114        11190 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.114, whole genome shotgun sequence.
ACCESSION   DAEPKC010000114 DAEPKC010000000
VERSION     DAEPKC010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11190)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11190)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11190
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.114"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            258..704
                     /locus_tag="KR294_003227"
     CDS             258..704
                     /locus_tag="KR294_003227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241282.1"
                     /translation="MAISDLAFGTECLKTSFQMLFSVISLVNINLLQAQILIAIGGLI
                     SILAMVSLTLFLSAKCKDSLTSMLIAFSICLIPMGIGVSWIGYLLPPGGIGFKISLLY
                     QMTSFNFLHLGGMSFWTPHIILFFSVIEIPIFIFLAIRTYCKHQVP"
     gene            1085..2002
                     /gene="pstC"
                     /locus_tag="KR294_003228"
     CDS             1085..2002
                     /gene="pstC"
                     /locus_tag="KR294_003228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HBH0241283.1"
                     /translation="MIVKSRLVGLEKNDNNGNKTKYVIEKVAKNIFLLSALVAVASLL
                     LIIGFVFYKGLRPFIFEGYSFIDFLTGADWVPSANKFGISSMIVASIFATLGALVIGV
                     PVGILTSVFIAEVAPKRLAKIMSPAVELLAGIPSVLYGVFGLAVIVPTIQGIFNLPKG
                     QSLLAIVIVLAVMMLPTIISVSETAIRAVPKAYKEGSLALGASKIETIFKVVLPAAKS
                     GVLAAVVLGVGRALGETMAVILVAGNSPVMPTAITDSVRPLTTNIALEMGYAFGTHQE
                     MLFATGVVLFTFILILNLVLNKLSNKAVN"
     gene            2004..2828
                     /gene="pstA"
                     /locus_tag="KR294_003229"
     CDS             2004..2828
                     /gene="pstA"
                     /locus_tag="KR294_003229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003460575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HBH0241284.1"
                     /translation="MRKFKENLLKSLVYLSALFTIVSLVVIVGFIFIKGIGNMNFNFL
                     FSNYSASGDGGILPMIITTLYTVVVSIVVATPIGILAAIYLQEYAKKGKAVTAIRFAT
                     ESLSGIPSIVYGLFGGIFFVVTLKMGYSIVAGSLTVAIIILPVIIRTTEEALKTVPQA
                     YRESSLALGATKFQTLYKVVLPSAIPGILSGVILSVGRIIGESAAILLTAGTVAKMPG
                     GIFDSARTLTVHSYLLTKESGDIATAASIGIVLIVIVLALNMLARFVAKKLNKANY"
     gene            2847..3611
                     /gene="pstB"
                     /locus_tag="KR294_003230"
     CDS             2847..3611
                     /gene="pstB"
                     /locus_tag="KR294_003230"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HBH0241285.1"
                     /translation="MELIDKIKMSVKDLDLFYGDKQALKKINMDIKENKVTALIGPSG
                     CGKSTFIRTLNRMNDLIEDVTIKGNISVDGEDIYTSDDVINLRTKVGMVFQKPNPFPM
                     SIYDNVAYGPRTHGLRDKKQLDKIVEESLKGAAIWDEVKDRLKSSALGLSGGQQQRIC
                     IARAIAMRPEVILMDEPTSALDPISTLKVEELIEDLKKDYTIVIVTHNMQQAARISDE
                     TAFFLNGEVIEFSDTKTMFTTPVDKRTEDYITGRFG"
     gene            3639..4292
                     /gene="phoU"
                     /locus_tag="KR294_003231"
     CDS             3639..4292
                     /gene="phoU"
                     /locus_tag="KR294_003231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HBH0241286.1"
                     /translation="MVNNSLDISIDTLKEQTVLMMEKCEEAIEKSVTCMIEKDLEGAR
                     KVVEDDEEINKLREEIRDKSIELIVLKQPMARDLRFIYSLGNISIELERIGDYAANIA
                     REMLKIGGEAYIKELIDIPKMAKECKSMMSQTREALILFDASIAYDVGTKDDIVDGLY
                     EQVQIDCLKIMHENSNTIDQGVKLLLIGRYLERIGDHITNVCEKIIFAIEGKMVEIG"
     gene            4450..5319
                     /locus_tag="KR294_003232"
     CDS             4450..5319
                     /locus_tag="KR294_003232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBH0241287.1"
                     /translation="MKLQKMGMRTIKTGISVTLCMILGDYLVENMFYSLVACIISVQD
                     TVKGSLKTGINRVEGTILGGIIGFIFAIIKAGDPFLCGLGVMCSIYLCNLFKIKSVVV
                     ACVTFLAIHLGVGNSDPVYYSLHRVLDTSVGVLFGVLVNYYVARPNYLNSVIDEFKKI
                     EELSMLLIEDKILRKENLNVEKFEEEVEKLEEIYSKLIDELDYSLSETNIEKIENALR
                     ICREIHFHMQSIELLENKLYLKEHTYKYLKKTYNVDKLDWNIDEEKSPVFNYHLMKIM
                     IEIELLRKLNKSY"
     gene            5406..6842
                     /locus_tag="KR294_003233"
     CDS             5406..6842
                     /locus_tag="KR294_003233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron hydrogenase"
                     /protein_id="HBH0241288.1"
                     /translation="MNTRNDNSKILEIYKMKLFGELVKAVWNDDIEDIENLPNKILNE
                     DLKDNLNNYFSGKFDKDTMVNLIRVTMGLDVTEDTDKNLKESLHEAVNLDEVKRPIIS
                     VISDACKYCDENNKEDESCKIRSKHINCNEEDVCSACGDCVSRCKLGAISDKIEFIPM
                     IKLLKDIKSPVYAIVAPAFVGQFGKDVSPGKLRTALKKIGFEDMIEVALAADMLTAKE
                     AYDYYEHMKKDEEGCFITSCCCPIWVSLIQNSFPQILENVSPSVSPMIACGRAVKILN
                     PDAKVVFIGPCMAKKKEAMLEDIKDAVDFVLTFKELQEIFDALELNPAIMDESNRVEA
                     SLSGRVYARTGGVSKAVKLSVRRIDKNIKFEEKAFEGTKECMDGLKKVLNKEIEATFI
                     EGMGCVGGCVGGPKRILSVEEGTKNVDEYSESTNMETPFDNLNVLQFLTSLGIKRVES
                     LGEKEEEKVKKIFSRDIKSNKKENKYKK"
     gene            6890..7717
                     /locus_tag="KR294_003234"
     CDS             6890..7717
                     /locus_tag="KR294_003234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBH0241289.1"
                     /translation="MKIKDNKAVFHVFIRIFLIAVLILTGTLLEEKINNVPVENISSK
                     GENTLELLSQSNTLGEIIYKASQEETKGPGATSEKVAYITIDDGPSKYTNALLDILKE
                     NDVKATFFMLNQNMKNHKEEVRRVLEEENSIGFHSVSHDIHKLYKSPEVTVGEFNTCN
                     NTLQEITGQSSKLIRLPYGSKPYMPEGSYNKLMANDYLIWDWNLDTQDWKSSTSQIVS
                     NILYYGRKRDELVVLIHEKEQSLNALNNIIRILKERGYTILPITENITPKNFWQENL"
     misc_binding    8013..8275
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            8351..11017
                     /locus_tag="KR294_003235"
     CDS             8351..11017
                     /locus_tag="KR294_003235"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HBH0241290.1"
                     /translation="MENTNLSKTYNPKDFEARLYKKWMDEGYFKSKPNPDKKPFTIMM
                     PPPNITGQLHMGHALDHTLQDILIRWKRMDGYEAFWLPGTDHASIATEVKVVERIKKQ
                     EGKTKYEIGREEFLKRAWEWKDEFGGKISNQLKQLGDSCDWDKERFTMDEGCNEAVIE
                     FFVSLYEKGHIYRGNRIINWCPDCKTTLSDAEVEHEEHDGNFYHIKYPLKDSEDFLEI
                     ATTRPETMIGDTGIAVNPEDDRYKHLIGKTAILPLVGRELPIVADSYVDLEFGTGAVK
                     MTPAHDPNDFEVGLRHNLEQLNTMNEDGTMNEVCGKYEGMDRFECRKAIVADLKEQGY
                     LIKIKEHNHNVGTCYRCHTVVEPRLSEQWFVKMEELAKPAIDILKKGELEFVPDKFDK
                     TYLQWLENIRDWCISRQLWWGHQIPAYYCQECGEIVVARKMPDKCPKCGSTHFKQDED
                     ALDTWFSSALWPFSTLGWPNKTEALDYYYPTSVLVTGYDIIFFWVVRMAFAGMFCMNE
                     KPFDHVLVHGLVRDSQGRKMSKSLGNGIDPLEIIEQYGADALRFTLTTGNSPGNDMRF
                     YMERVEFARNFANKLWNASRFVFMNIDEDIIKNMTRESVKEDLTLADKWIISRANNIV
                     KEATNNMDKFDLGIALQKIYDFTWSEYCDWYIEMVKPRLYGEDANAKSAALYTLTYVL
                     EKILKLLHPYMPFITEEIYTHLPTVEGCIIVSEWPKYNEEDNMAEEEDMMNLLMEGIR
                     SIRNVRAEMNVPPSKKAKLIIIPSEEKIEAIELGKDYFITLASASNVEIAKDKSNVPE
                     DAVGVVIDGVEIFIPLNELVDFEKEIERLSKEKKKLEGEIKRVNGKLANQGFLAKAPE
                     SLIEEEKAKKEKFEEMIKSVEERLTNLESKIK"
BASE COUNT         4419 a         1196 c         2090 g         3485 t
ORIGIN      
        1 taaaatagtt aaataataag attaagaatt tcttaataaa tccagaagat gctttcgatt
       61 atataatatt ttatattttt atattattaa ttatatgtgt tgcaatcgct gcacctactt
      121 tttctggtga gtatcagaca caatcagata gcatccttcg ttgtacgaaa catggacata
      181 ttcgtctagc gtttactaaa atattagctc tattttctat atttataata atgtttgtta
      241 tatgtatttc tatccatttg gcaatttctg atttagcttt tggtactgaa tgtttgaaaa
      301 cctcatttca aatgttgttt tctgtcatta gtctagtaaa tataaattta ctacaagcac
      361 agattcttat agctattggt ggtctaattt caatacttgc aatggttagt ttaacattat
      421 ttttatctgc aaaatgtaag gattctctta cttctatgct gattgctttt tctatttgct
      481 taattcctat gggaataggt gttagttgga ttggatacct attaccacca gggggaattg
      541 gttttaagat tagtttatta tatcaaatga catcatttaa tttcttacac ttaggaggta
      601 tgagtttttg gacaccacac attatactgt ttttctcagt gatagaaata cctattttta
      661 tatttttggc tattcgtacc tattgcaaac atcaagtacc gtaacaattt gatggaaata
      721 atagtgatat aaactagagg atacaataat tatatatgta gtataaaagt taaatttagt
      781 taacaaatct taatagcaga tataggtaat aaattataca taaactgtat tattatctat
      841 atctgctatt ttaatataga gaaacaacag tatattgtaa agtaaatgtc aaatatagtt
      901 ttaaaagtaa aattaatgtt aaaaagtaaa tataatttta cacttgctta acttaatcct
      961 aatatagatt taacttaaaa aaagtagaat aaaagtatag gaaatttgat gaagacgaat
     1021 tataaaaaat taaattttga atacagaacg aaaatcgata agtatatttt aatgggaggg
     1081 tattatgata gtaaaatcta gattagtagg tttagaaaaa aatgacaata atggcaataa
     1141 gacaaaatac gtaattgaaa aagtagcaaa aaatattttt ctacttagtg ctttagtagc
     1201 agttgcaagt ttacttttga taataggatt cgtattttat aaaggattaa gaccatttat
     1261 atttgaagga tattcattta tagacttttt aactggtgca gattgggttc cttctgccaa
     1321 taaatttgga atatcatcta tgatagtagc atcaatattt gcaacacttg gagcacttgt
     1381 tataggagta cctgttggta tattaacctc tgtatttata gcagaagtag cacctaaaag
     1441 attagcaaaa ataatgtcac cagcagttga acttttagca ggtatacctt cagtattata
     1501 tggtgtattt ggtcttgcag tgatagttcc aactatacaa ggtatattta atcttccaaa
     1561 aggtcaaagt ttgttagcaa tagtaatagt attagcagta atgatgttac caacaataat
     1621 atctgtatca gaaacagcaa taagagcagt accaaaagca tacaaagaag gttcattagc
     1681 acttggtgca tcaaaaatag aaacaatatt caaagttgta ttacctgctg caaaatctgg
     1741 agtattagcc gcagtagtgt taggagtagg aagagcttta ggtgaaacaa tggcagtaat
     1801 acttgttgca ggcaactcac cagttatgcc aactgcaata acagatagtg taagaccact
     1861 tacaactaat atagcacttg aaatgggata cgcatttggt acacatcaag aaatgctatt
     1921 tgcaactgga gtagtattgt ttacatttat attaatttta aacttagttt taaataaact
     1981 ttcaaataag gcggtaaatt aagatgagaa agttcaaaga gaatctattg aagtcattag
     2041 tatatctatc agcactattt acaatagtat cattagtagt tatagtggga tttatattta
     2101 taaagggaat tggcaacatg aattttaatt tcttatttag caattattca gcatcaggtg
     2161 atggtggtat acttccaatg ataattacaa cattatatac agtagtagtt tctatagttg
     2221 tagcaactcc tataggaata ttggctgcta tatatttaca agaatatgct aaaaaaggaa
     2281 aagcagttac agctataaga tttgcaactg aaagtttatc agggatacca tctatagtat
     2341 atggattatt tggaggaatt ttctttgtag ttacattaaa aatgggatat tccatagttg
     2401 caggttcact tacagttgca ataataatat taccagtaat aattcgtaca acagaagaag
     2461 ctttaaaaac agttcctcaa gcttatagag aatcatcatt ggcattagga gctacaaaat
     2521 ttcaaacttt atataaggta gtacttccaa gtgcaatacc aggaatttta tctggagtaa
     2581 tcttatcagt tggtcgtata attggagaat cagctgcaat attacttaca gcaggtactg
     2641 tagccaagat gccaggtgga atatttgata gtgcaagaac attaactgta cactcatact
     2701 tactgactaa agagagtgga gatatagcaa cagcagccag tataggaatt gttttaatag
     2761 taattgtatt agcactaaac atgctagcaa gatttgttgc taagaaatta aataaagcta
     2821 attattaaat ttaagaggtg tgaataatgg aattaatcga taagataaaa atgagtgtaa
     2881 aagatttgga tttattttat ggtgataagc aagcattaaa gaaaataaat atggatataa
     2941 aagagaataa ggttactgct ttaataggtc catctggatg cggaaaatca acttttataa
     3001 gaacgttaaa tagaatgaat gacttaatcg aagatgtaac aattaaagga aacatttctg
     3061 ttgatggaga ggacatatat acctcagatg atgttataaa tcttcgtact aaagtaggaa
     3121 tggtatttca aaagccaaat ccatttccta tgagtatata tgataatgtg gcatatggtc
     3181 ctcgtacaca tggactaaga gataagaagc aattagataa aattgtagaa gaaagcttaa
     3241 aaggtgcagc tatttgggat gaggttaaag acaggcttaa atcatctgca ctaggacttt
     3301 ctggtggtca acaacagcgt atatgtatag caagagcaat tgctatgaga ccagaagtta
     3361 ttcttatgga tgaacctaca tctgctttag acccaatttc aacattaaaa gtagaggaac
     3421 ttatagagga tttaaaaaaa gactacacaa tagtcatagt tacacataat atgcaacaag
     3481 ctgctcgtat atcagatgaa acagcttttt tcttaaatgg agaggttata gaatttagcg
     3541 atacaaaaac tatgtttacc actcctgtag ataaaagaac agaagactat ataacaggta
     3601 gatttggtta aaatatataa ctataaagga gttagacaat ggtcaataat agtttagata
     3661 taagtattga tactttaaaa gaacaaacag tgcttatgat ggaaaaatgt gaagaagcaa
     3721 tagaaaagtc tgtgacttgt atgatagaga aggatttaga gggtgcaaga aaagtagtag
     3781 aagatgatga agaaataaat aaattaagag aagaaataag agataagagt atagagctaa
     3841 tagtattaaa gcaaccaatg gcaagggact taagatttat ttattcatta ggtaatatat
     3901 ctatagagct ggaaagaata ggagattatg cagcaaatat agctagagaa atgttgaaga
     3961 taggtggaga ggcttatata aaagagctaa tagatattcc taagatggca aaagaatgta
     4021 agtctatgat gtctcagact agagaagctt taatcttatt tgatgcaagt atagcttatg
     4081 atgttggaac taaagatgat attgtagatg gattgtatga acaagtacaa attgattgtt
     4141 taaaaataat gcatgaaaac tcaaatacca tagaccaagg ggtaaaactt ctacttatag
     4201 gaagatacct tgaaagaatt ggagaccata taacaaatgt atgtgagaag ataatttttg
     4261 caattgaggg taaaatggtt gagataggat aaaaaactgc tttaaagcag tttttttatt
     4321 gtctaaatta agaaagaatt gataaaaaaa tatgattaat gggtaaattt aaaaaattgt
     4381 gatatactag gaacatatta aatatgagga tgcgtatttt atataaggtg ctttttagga
     4441 ggtggaactt tgaaacttca aaagatgggt atgaggacta taaaaacagg aattagtgtc
     4501 actttatgta tgattcttgg tgactattta gtagagaata tgttttattc tctggtagca
     4561 tgtataattt ctgttcaaga tacagtaaaa ggttctttaa agacgggaat caatagagtg
     4621 gaaggtacta ttttaggtgg tataatagga ttcatatttg caatcattaa agctggagac
     4681 ccatttttat gtggtctagg agtaatgtgc tcaatatatt tatgcaatct gtttaaaata
     4741 aagtcagtag tagttgcctg tgtaaccttt ctggctatac atctaggtgt aggaaatagt
     4801 gaccctgtgt attattcttt acatagggtg ttagatacat ctgtgggtgt tttgtttgga
     4861 gtacttgtta attattatgt tgctagacca aattatctaa atagtgttat agatgagttt
     4921 aaaaagatag aagaactttc aatgttgctt attgaagata aaattcttag aaaagaaaat
     4981 ttaaatgtag agaaatttga agaagaagta gaaaaattag aagaaatata ttcaaaactt
     5041 attgatgagt tggattatag tttgagtgaa actaatatag aaaaaattga gaatgcctta
     5101 aggatatgta gagaaataca ttttcatatg cagtctatag agttacttga aaataaactt
     5161 tatttgaaag agcatacata taaatacctt aagaaaacat ataatgtgga taagctagac
     5221 tggaatatag atgaagaaaa aagccctgta ttcaactatc atctaatgaa aataatgatt
     5281 gaaatagagt tgttgagaaa gctaaataaa tcatattaat aatagtagtt aaataataaa
     5341 taaaaaatag tatctttgta aatattaaac atatataagt ttaatttatg gaggtactat
     5401 tttttatgaa tactagaaat gacaattcta aaatactaga aatatataaa atgaagcttt
     5461 ttggcgaact tgtaaaagca gtgtggaatg atgatataga ggatattgaa aacttaccta
     5521 ataaaatttt aaatgaagat ttaaaggata atttaaataa ttattttagt ggaaaatttg
     5581 ataaagatac tatggtaaat ttaattaggg taactatggg attggatgtt acagaagata
     5641 cagataaaaa tttaaaagag tcactgcatg aagctgtaaa tttagatgaa gtcaaaagac
     5701 caataatatc tgtaatatca gatgcttgca aatattgtga tgaaaataat aaggaagatg
     5761 agtcatgtaa gataagaagt aagcatatta attgtaatga ggaagatgta tgtagtgctt
     5821 gtggtgattg tgtatcaaga tgtaagttgg gtgcaatttc agataaaata gaatttatac
     5881 caatgataaa attgttaaaa gatataaaga gccctgtata tgcaatagtt gcaccagctt
     5941 ttgtaggaca gtttgggaaa gatgtaagcc ctggtaaatt aagaactgca ttaaaaaaga
     6001 taggatttga agatatgata gaagttgctt tggcagcaga tatgcttact gcaaaagaag
     6061 catatgatta ttatgagcat atgaaaaagg acgaagaagg atgctttata actagttgtt
     6121 gctgtcctat ttgggttagt ttgatacaaa atagttttcc tcagatattg gaaaatgtat
     6181 caccatccgt ttctcctatg attgcttgtg ggagagctgt aaaaatttta aatccagatg
     6241 ctaaagttgt attcataggt ccttgtatgg caaaaaagaa agaagcaatg ttagaagata
     6301 taaaagatgc agttgatttt gtgcttacat ttaaagagtt gcaagaaata tttgatgcat
     6361 tagagttaaa tccagcaata atggatgaga gtaatagagt agaggcgtcc ctttcaggta
     6421 gagtttatgc tagaacagga ggtgtaagta aagcagttaa gttatcagtt agaagaattg
     6481 acaaaaatat aaaatttgaa gaaaaggcat ttgaaggaac aaaagagtgc atggacggtc
     6541 taaagaaagt tctaaataaa gaaatagaag ctacatttat agaaggaatg gggtgtgtag
     6601 gaggctgtgt aggaggtccg aagcgtattt taagtgtgga agaaggtact aagaatgttg
     6661 atgaatatag tgaaagtacg aatatggaaa ctccatttga taatttaaat gtattacaat
     6721 ttttaacttc tttgggaatc aaaagagtag aatctttagg agaaaaagaa gaagaaaagg
     6781 ttaaaaaaat atttagtaga gatataaaaa gtaataagaa agagaataaa tataaaaaat
     6841 aactttttaa gtcttaaact tatgctttta taaaagggag atatggggga tgaaaattaa
     6901 agataataag gctgtttttc atgtatttat aaggatattt cttatagctg ttttaatttt
     6961 aactggaaca ttattggagg aaaaaattaa taatgttcca gttgaaaata taagttcaaa
     7021 aggtgaaaat acactggaac tgctttctca aagtaatact ttaggagaaa tcatatacaa
     7081 agcatctcaa gaagaaacaa aaggtccagg ggctacttct gaaaaagtag catacataac
     7141 aatagatgat ggtccatcaa aatatacaaa tgcactactt gatattttaa aagaaaatga
     7201 tgtcaaagcg acatttttca tgcttaatca gaatatgaaa aaccacaagg aagaagtaag
     7261 gagagtcttg gaagaagaaa actcaatagg ttttcatagt gtaagtcatg atatacataa
     7321 gttatataaa agcccagaag taacagttgg ggaatttaat acatgcaata atactctaca
     7381 agaaataact ggtcagagtt caaaattaat aagattacca tacggaagta aaccatatat
     7441 gccagaaggt tcatataata aacttatggc aaatgattat ttaatttggg actggaattt
     7501 ggatacacag gattggaagt cttctacaag tcagatagta agtaatatat tatattatgg
     7561 aagaaaaaga gatgaattag tagtattaat tcatgagaaa gagcaaagtt taaatgcttt
     7621 aaataatatt ataagaatct taaaagagag aggatataca atattgccaa ttacagaaaa
     7681 tataacacct aaaaatttct ggcaagaaaa cttataataa atttaaatat agtaaaagat
     7741 aaagtaaatt atttataaaa taaaacatat aatataaaaa atacgaataa gaggtatact
     7801 gtaaggataa tataaaatta atgagaaagc attaaaatta aaataaaata atcttgcaat
     7861 tattgacatt ataagacaga ataactgtaa aaacatattt taaaatataa caactatata
     7921 aaagagaata gacataatta agaaaattca gaaaaaataa aataaaaata attgacaaag
     7981 agaataatat ttgtatataa taatatgtaa tattaaagac tgagaagaag aggagtaagt
     8041 aaatactact aaaagagagg aaaattcact ggctgtaaga ttttctaagt ataagattta
     8101 ctgaatgtag ctttggagtt tctaaactga actataagta agtttagacg gttagaaccg
     8161 ttaaattctt tgagagtcaa agttgataaa ataacattaa ccaataattt aattatatgt
     8221 taatgtattt taagctttgg aattaaggtg gtaacgcgag cttttcgtcc tttttaaaga
     8281 ggatgaagag ctctttttta tttctaaaga tatttaaaaa atttatttat aaaatacagg
     8341 aggcaggaca atggaaaata cgaatttatc aaaaacttat aacccaaaag attttgaggc
     8401 taggctatat aaaaaatgga tggatgaagg gtattttaaa tctaaaccaa atccagataa
     8461 aaaaccattt acaataatga tgccaccacc aaatataaca gggcaattgc atatgggaca
     8521 cgctcttgac catacacttc aagatatatt aatcagatgg aaacgtatgg atggatatga
     8581 agctttttgg cttccaggaa ctgaccatgc ttctatagca acagaagtta aagttgttga
     8641 aagaataaaa aaacaagaag gcaagacaaa gtatgaaata ggtagagaag aatttttaaa
     8701 gagagcctgg gaatggaaag atgaatttgg aggaaaaata tctaatcagc ttaaacaact
     8761 aggtgattct tgtgattggg ataaagaaag atttactatg gatgaagggt gtaatgaagc
     8821 agttatagaa ttttttgtaa gcctatatga aaaaggtcac atatacagag gaaatagaat
     8881 aataaactgg tgcccagatt gcaaaactac tttatcagat gcagaagttg aacatgaaga
     8941 acacgacgga aacttttatc atataaagta cccactaaaa gatagtgaag actttttaga
     9001 aatagctaca actagacctg agacaatgat aggagatact ggtatagcag taaatccaga
     9061 agatgataga tataaacatt taataggaaa aacagcaata cttccattag taggaagaga
     9121 acttccaata gttgcagata gttatgttga tttagagttt ggaactggtg cagttaagat
     9181 gactccagca catgacccta atgattttga agtaggatta agacataatc ttgagcagtt
     9241 aaatactatg aatgaagatg gaactatgaa tgaagtttgt ggaaaatatg aaggtatgga
     9301 tagatttgag tgtagaaaag ctatcgtagc agacttaaaa gaacaaggtt acctaattaa
     9361 gataaaagag cataatcata atgtaggaac ttgttataga tgccatacag tagttgagcc
     9421 tagattatca gagcaatggt ttgttaagat ggaagaactt gcaaaaccag ctatagatat
     9481 tcttaaaaaa ggagaattag aatttgttcc agataaattt gataaaactt atttacaatg
     9541 gctagaaaat ataagagatt ggtgtatatc aagacaatta tggtggggtc atcaaatacc
     9601 agcttattat tgtcaagagt gtggagaaat agtagttgct agaaaaatgc cagataagtg
     9661 tcctaaatgt ggaagcactc attttaaaca agatgaagat gccttagata cttggttcag
     9721 ttctgcatta tggcctttct ctactctagg atggccaaat aagactgaag ctttagatta
     9781 ttattatcca acaagtgtac ttgttacagg atacgatata atattcttct gggtagttag
     9841 aatggcattt gcaggtatgt tctgtatgaa tgaaaagcca tttgaccatg ttttggttca
     9901 tggattagta agagattctc aaggtagaaa aatgagtaaa tctttaggaa atggtatcga
     9961 cccattggag ataatcgagc aatatggagc tgatgcccta agatttacat taacaactgg
    10021 aaattcccca ggaaatgata tgagattcta tatggaaaga gtagaatttg ctagaaactt
    10081 tgcaaataag ttgtggaatg catcaagatt tgtatttatg aatattgatg aagatataat
    10141 taaaaacatg actagagaaa gtgttaaaga ggacttaact ctagctgata aatggataat
    10201 atcaagagca aataatattg taaaagaagc aactaataac atggataagt ttgatttagg
    10261 aatagcactt caaaagatat acgattttac ttggtcagaa tactgtgact ggtatattga
    10321 aatggttaaa cctagattat atggggaaga tgcaaatgct aaatctgcag cattatatac
    10381 attaacttat gttcttgaaa agatattaaa attattacat ccatatatgc catttataac
    10441 agaggaaata tatactcatc ttcctactgt tgaaggatgt ataatagtat ctgaatggcc
    10501 aaaatataat gaagaagata acatggctga agaagaagat atgatgaact tattgatgga
    10561 aggtataaga agtataagaa atgtgagagc agaaatgaat gtaccacctt ctaagaaagc
    10621 taaattgata ataatcccaa gtgaagaaaa aatagaagct attgagcttg gtaaagacta
    10681 ttttataact ttagcatctg cttcaaatgt agagatagca aaagataaat ctaatgttcc
    10741 agaagatgca gttggagtag ttattgatgg tgttgaaata tttatacctc ttaatgaatt
    10801 agttgatttt gaaaaagaaa ttgagagatt atctaaagaa aagaaaaagt tagaaggcga
    10861 aataaagaga gttaatggaa agcttgcaaa tcaaggtttc ttagcaaaag ctcctgaaag
    10921 tttaattgaa gaagaaaaag caaaaaaaga aaaatttgaa gagatgatta aatctgttga
    10981 ggaaagatta acaaatttag aatctaaaat aaaataaata taagaattag taaaaacata
    11041 caaaaagtat atattctata ctttttgtat gtttttcttt atatatatac aaatatgatg
    11101 ttataattct ttacagatgt gttatatttt tattttatgt tgtgaatata tgaattttat
    11161 gtcttaaaat ttataagcaa taaaaatttg
//
LOCUS       DAEPKC010000115        11066 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.115, whole genome shotgun sequence.
ACCESSION   DAEPKC010000115 DAEPKC010000000
VERSION     DAEPKC010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11066)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11066)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11066
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.115"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            32..1144
                     /locus_tag="KR294_003236"
     CDS             32..1144
                     /locus_tag="KR294_003236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5009 domain-containing protein"
                     /protein_id="HBH0241291.1"
                     /translation="MNSRIKSIDIIRGLSIALMIVCNNPGTWMRMYPQLRHAVWHGVT
                     LADFAFPFFVISLGVTIPISINSKLKNNKSTLSIIFSIFKRSILLILFGFFLNYLGNP
                     NLDTVRILGVLQRMGLVYFVTSLVYLLLKKLNVGSAATIITFLCISTFIIVGYYILAK
                     PYGFELEGSLAQLVDLHFFKGHLYKPEFEPDGFLTSIVAISSGMLGCTMGCVLLKEDI
                     GEYKKFFKILVMSIILLIGAFIFNQYFPFNKRLWSSSFVLLMAGSYGVLLSIFYFICD
                     IKNKSKIFTPIIALGSSPIFTYMCLEILSHVFWNVPKLTNKVDYPTTLVEWTTYELIT
                     PWAGTTWDSLVFSLLYVLFWVIVMSIMYKKKIFIKI"
     gene            1398..3422
                     /locus_tag="KR294_003237"
     CDS             1398..3422
                     /locus_tag="KR294_003237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBH0241292.1"
                     /translation="MKKTTKLLATGMLSVAMVAPNVALAAENTTANTESNSDININLQ
                     RKSVVLGSKSNASVKFKEKLNADSITLNFMCYDMPLEATLNYNEKTDSYEGVINYNKD
                     PEYLNVWELQSIKINGKDEQKVLNKEDLESMGLNLKDYDVTQEFIISDANSTKAVNEY
                     MRKTSAPVKKLAGATRFETAVEISKQGWKDGSSKVVIVNGELAADGITATPLASTYDA
                     PILLANKDDIPESTKAELKRLNPSDVIIIGDDGSVSQKAVSQIKSAVNVNVTRIGGVD
                     RHETSLLIAKEIDKYHDVNKIYIANGYAGEYDALNISSKAGEDQQPIILANKDSVPQG
                     TYNWLSSQGLEEAYYIGGSQSLSSKLIDQISKIAKNGTSKNRVSGADRHETNANVIKT
                     FYPDKELSAMLVAKSDIIVDSITAGPLAAKLKAPILITPKTYVSAYHNTNLSEKTAET
                     VYQIGDGMKDSVINSIASSLSKHNAPTEPDNSGSAAGKTVVIDPGHGGSDSGATSGLN
                     GGAQEKKYTLNTALATTEYLRSKGINVVMTRDTDKTMALGERTALSNTIKPDLFTSIH
                     YNASNGSGNGVEIYYKVKDKNGGTTKTAASNILKRILEKFNMKNRGIKTRTLDNGKDY
                     LYVLRNNNYPAILVECAFIDNKSDMDELNTAEKVKTMGTQIGIGIEDTVK"
     gene            3642..4328
                     /locus_tag="KR294_003238"
     CDS             3642..4328
                     /locus_tag="KR294_003238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HBH0241293.1"
                     /translation="MSGYTNDECEIPKIKSYPGADKEIASEIDYSIVKGTVLFDLYQR
                     IMDLVLSIIGLVIGLPLIAIFGILIKIEDKGPITYKQERLGKCGRRFYIYKLRSMRTD
                     AEKFGAQWAEKDDPRITKVGKFIRKTRIDEIPQLFNILKGDMGLIGPRPERPNFTVQF
                     NEEIPGFINRLAIKPGLTGWAQVNGGYEITPEEKLKEDIYYIKNRSILLDFKILFKTV
                     KVVLTGDGAR"
     gene            4423..5478
                     /locus_tag="KR294_003239"
     CDS             4423..5478
                     /locus_tag="KR294_003239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp7"
                     /protein_id="HBH0241294.1"
                     /translation="MIKKISTILSLVLLISISSTIGVFADANPKRELIEGSIPEISTE
                     LNKRAFKDSKEVILVNEESIVDSISATPLAYAKNAPIVVTKSKNLGRVTRNYLKELGP
                     EKVTIVGGLKAVSKDAERNIEKMGMKVERIRGKDRYDTSLKIAREMYRTVGFDEAFLL
                     SSTTGLENAISVYSYAAKSGMPIIWAKDEGFEEQIDFLKGKNLKKIYALGDSKEFIAE
                     IDSNLKNIEGIKQINKSSTNVDLIKKFYDEKDIKKIYTARLDFGSRSDVNEYISLGVV
                     SAKENMPILICSDNLSRAQDKFLKDSNINDVVEVGYTVGDYSLFRSIFNLTFLSCIVL
                     ILLLLLITFRALRYESK"
     gene            5593..7149
                     /gene="murJ"
                     /locus_tag="KR294_003240"
     CDS             5593..7149
                     /gene="murJ"
                     /locus_tag="KR294_003240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein biosynthesis integral membrane protein
                     MurJ"
                     /protein_id="HBH0241295.1"
                     /translation="MSKTAKAALWIMAATMFSKVLGFLRELVLANFYGTGMYADVFVL
                     TLNIPGLIIAVIGSAVATTYIPMYFETKKRLGDEGALKFTNNVLNICYIMAIVIAIIG
                     LLFTEQFVTVFAAGFRNDPAKFQAAILFTKIMISGVLFLSGSKIFSSFLQVNDSFVIP
                     GLIGIPYNIIIIAAIALSAGKNVWILPAGALLAMASQLLFQLPFAFKKSYKYKPYINL
                     KDESIKELVNLVLPMLVGVAVGQLNIFVDRLLATTLGNGKLSALNYANRLNEFVMALF
                     VTSIITVIYPKLAKMSGKDNKEGFISTIVKSSNCIILVVLPISIGAIILAEPLVRILF
                     QRGKFDALSTDLTSIALRLYSLGLLACGVRDVLYRAFYSLSDTKTPMINGSIALIINI
                     VLNLILIRPLGHAGIAISTSTSNIITVILLFISLKKKNGYFGGDKIIKTGLKSLVASG
                     VMAVATLLIYNNLYAFMGSGTIKEIISVGAGVLGGASVYTVLIVLFKVEEMDLAFEFL
                     RKGKQKLLRR"
     gene            7195..8901
                     /locus_tag="KR294_003241"
     CDS             7195..8901
                     /locus_tag="KR294_003241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HBH0241296.1"
                     /translation="MDYKNNYEMWLNSPYFDEQTKNELLSIKDDEKEIQDRFYKNLEF
                     GTGGLRGIIGAGTNRINIYTVRRATLGVLNYIMKTQGEEGKQKGIVIAHDSRYMSREF
                     CIEVAKTLSAYGVKAYIFEELKPTPELSFAVRYLKCAMGIVITASHNPKEYNGYKVYD
                     SDGGQICIDMANDIIAEVNKIDDYSIIKSIDFEEALSKNLITILDNEVDDEFIKAVKK
                     QVLRQNIIDECGKKLKIIYTPIHGTGNKPVRKVLNECGFENVMVVKEQELPDSNFSTV
                     NYPNPEEKSVFNIAIEMAKNNGTDLIIGTDPDCDRVGIVVKDSSGEYVVLNGNQVGSL
                     LVRYILESLVEENKLPKNNPTIIKTIVTSELGAKIAKAYNVDCLNTLTGFKFIGEKIK
                     AFEESNDRSFIMGYEESYGYLIGTHARDKDGVVSSLMICEMAAYYSSKGMNLYEALID
                     TYNKFGYYKEDLKSVTLKGIDGIKKIKEMMLYFRSVKIDNVADVKVDKILDYKDGVDD
                     LPKSDVLKFLLEDGSWIAIRPSGTEPKIKFYFGANSDNQEDVEFKLNNLISYILNVVD
                     SI"
     gene            8923..9996
                     /locus_tag="KR294_003242"
     CDS             8923..9996
                     /locus_tag="KR294_003242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-1-phosphate guanylyltransferase"
                     /protein_id="HBH0241297.1"
                     /translation="MKVYNVIMAGGGGTRFWPLSRQEVPKQLINLSGEDALINETINR
                     IDSLAKKDDLFIVTNEKQLEALKDIVKDKCLDSNILPEPCARNTAAAIGFAAFNIMKK
                     YGDGVMCVYPADHYIKDEKEFKSILEKAIYIAENNDKLVTIGITPTFPSTGYGYINFN
                     RENTIEDVAYEVVEFVEKPNYEIAKEYVNSKKYVWNSGMFVWKVSKILEDFKRYLPKV
                     YEKLEDISKYLGTKEEMEKIKEIYPTIQSISIDYGIMERSNDVIVVPGDFGWNDVGSW
                     DSLGAIYPTDDEGNIKRGENITIDTKNSIIYSDDKLISTIGISDLIVVSTNDAVMVCR
                     KDKAQDVKKIVEQLKEEDRQEYM"
     gene            10008..10730
                     /locus_tag="KR294_003243"
     CDS             10008..10730
                     /locus_tag="KR294_003243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBH0241298.1"
                     /translation="MIPKKIHYVWFGGPKGNIENICINSWKEKLPEYEIVEWNEKNFD
                     IEKEIKGNKFLEECYKRKLWAFISDYTRIKVLYEQGGVYMDTDMQILKDITPLLENNR
                     LICGYEDDREYINGAIIGVEKGHPFLKDLLEYYEKEVLTSSLFTIPKIMTHLMEKNYK
                     KIDPNNYEEGIRVYDKEYFYPFGFKEDFTPECITENTFGIHWWGKSWAKKRNYFLESK
                     HLTGVNKIWKCCKIFASNTLRS"
     gene            10746..>11066
                     /locus_tag="KR294_003244"
     CDS             10746..>11066
                     /locus_tag="KR294_003244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide polymerase"
                     /protein_id="HBH0241299.1"
                     /translation="MKTLNDDRNIMIRKYLYIFVLFIILLRKYMISFIDPNMDIGMIK
                     SALFYSSIGILMLLFLFDKRKSITEMVLVGVCVLLYLLNREGAILLIVLLAVSAKQID
                     DKFIV"
BASE COUNT         4367 a         1218 c         2040 g         3441 t
ORIGIN      
        1 aatttcaaat aatgctgtag attctaaact tatgaatagt aggattaagt caatagatat
       61 aataagaggg ctatcaatag ccctcatgat agtctgcaat aatcctggga cttggatgag
      121 aatgtatcct caattaagac atgctgtatg gcatggtgta acacttgcag attttgcatt
      181 tccttttttt gttatatctt taggtgttac aattccaata tcaataaata gtaaactaaa
      241 aaataataaa tccacactga gtataatatt tagtatattc aagagaagta tcttattgat
      301 attatttgga tttttcttaa attacctagg aaatcctaat ttagatactg taagaatact
      361 tggagtactt caacgtatgg gattagtcta ttttgtgact agtttagtat atttactact
      421 aaaaaaatta aatgttggaa gtgctgctac aataattact ttcttatgta tatctacatt
      481 tataatagtt gggtactaca tattagcaaa accttatgga tttgagctag aaggttctct
      541 tgcacagtta gtggatttac atttcttcaa aggacatttg tacaagccag aatttgaacc
      601 agatgggttt ttaactagta tagtagcaat ttcttcaggt atgttgggat gcactatggg
      661 atgtgtactt ttaaaagaag acataggaga atataaaaaa ttctttaaaa tactggttat
      721 gagcataatc ctgctaatag gtgcttttat ctttaatcag tattttccat ttaataaaag
      781 attatggtct agctcatttg tacttttaat ggccggtagt tatggtgtat tactgtcaat
      841 attttatttt atatgcgaca tcaaaaataa aagtaaaata tttaccccaa taatagcact
      901 tggaagtagc cctattttta catatatgtg ccttgagata ttgagtcatg ttttttggaa
      961 tgttccaaaa cttacgaaca aagtcgatta tccaactacc ttggtagagt ggactacata
     1021 tgaacttata acaccttggg caggtacaac ttgggattct cttgtatttt ctttattgta
     1081 tgtcctattc tgggttatag taatgtctat aatgtacaag aaaaaaatat ttattaaaat
     1141 ttagtgcaat atttttagac gataaagtct ttgatttgtt caaatatacg gaaactatca
     1201 aatataatca aaatttctcc tcgataaaat ttaaaaacca tgccataaaa gattacaaaa
     1261 agtttacaat ttgtaatttt ttgtgctata atgaaaaaag atttacataa tattgaattt
     1321 atgtaatata aaacaagctt aagatgtatt aaaaaagatt taaagagtta aagaaccaaa
     1381 aaattagggg ggatatgatg aaaaaaacaa caaaattatt ggcaacagga atgctgtctg
     1441 tggcaatggt ggcaccaaac gtagctttag cggctgaaaa tactactgca aatacagaat
     1501 ctaattcaga tattaatata aatttacaaa gaaaaagtgt agtgttagga agtaaatcta
     1561 atgcaagtgt aaaatttaaa gaaaaattaa atgctgattc aatcacatta aattttatgt
     1621 gttatgatat gccacttgaa gctactttaa attacaatga aaagacagat tcatatgaag
     1681 gtgtaataaa ctataacaaa gacccagaat acttaaatgt atgggaactt caaagcataa
     1741 aaataaatgg taaggatgaa cagaaagttt taaacaaaga agacttagag tctatgggat
     1801 taaatcttaa ggattatgat gttacacaag agtttataat aagtgatgca aattcaacaa
     1861 aagcagtaaa tgaatatatg agaaaaactt ctgcaccagt aaaaaaactt gctggagcta
     1921 ctagatttga aactgctgtt gagataagta aacaaggttg gaaagatggg tctagtaagg
     1981 ttgtaatagt taatggagaa ttagcagcag atggaattac agctactcca cttgcatcta
     2041 catatgacgc accaatatta cttgcaaata aagatgatat accagaaagt acaaaagcag
     2101 agttaaaacg tctaaatcca agtgatgtaa taattatagg tgatgatggt tcagtttcac
     2161 aaaaggcagt gtctcaaatt aaatctgctg taaatgtaaa tgtgactcgt attggtggag
     2221 ttgatagaca tgaaacatct ttacttatag caaaagaaat agataagtat catgatgtta
     2281 ataaaatata catagcaaat ggatatgctg gtgaatatga tgctcttaat atttcatcaa
     2341 aagctggtga agaccaacaa cctataatat tagctaataa agattctgta ccacaaggta
     2401 catataattg gttatcttca caaggtttag aagaagctta ttacataggt ggtagtcaaa
     2461 gtttatcatc aaaacttata gaccaaatat ctaaaatagc aaaaaatggt acttcaaaaa
     2521 atagagtttc tggagcagat agacatgaaa caaatgcaaa tgtaattaag actttctatc
     2581 cagataaaga gttgagtgca atgttagttg caaaatctga cataatagtt gattcaataa
     2641 cagcaggacc tttagcagct aaattaaaag ctccaatact tataactcca aagacttatg
     2701 tttctgcata ccacaataca aatttatcag aaaaaacagc agaaacagta tatcaaattg
     2761 gtgatggaat gaaagatagt gttataaatt ctatagcatc tagtttatca aaacacaatg
     2821 caccaacaga accagataat tcaggttcag cagcaggaaa aactgtagtg atagacccag
     2881 gtcatggggg ttctgattca ggggcaacaa gtggattaaa tggtggagca caagaaaaga
     2941 aatatactct taatacagca ttagcaacta ctgaatattt acgttcaaaa ggtataaatg
     3001 ttgttatgac tagagataca gataaaacaa tggctttagg agaaagaaca gcattatcaa
     3061 atactataaa gccagattta tttacaagta tacattacaa tgcgtctaat ggatctggta
     3121 atggtgtgga aatttattac aaagtaaaag ataaaaatgg tggaacaact aagactgcag
     3181 catcaaatat cttaaaaaga atactagaaa aatttaacat gaaaaataga ggaatcaaga
     3241 caagaacact tgataatgga aaagattacc tatatgtgtt aagaaataat aattatccag
     3301 caatacttgt tgaatgtgca tttattgaca ataagagcga tatggatgag ttaaatactg
     3361 cagaaaaagt aaaaacaatg ggaactcaaa ttggaatagg aatagaagat acagtaaaat
     3421 aaaataaaaa atattaaagc aaaacatatc atctcctgtt ataatgtaaa atataacaag
     3481 agatgatata tttttgtaaa gaatcaaatt gtttacaatg atgtttcttg tattgataat
     3541 ctgctcatta ttgagtataa tatagaaata agtcaaaaat aagatagaaa taagttgaaa
     3601 ttaagaatta aaaaaatttt tattccaata tggaggtaac tatgtctgga tatactaatg
     3661 atgagtgtga aatacctaaa attaaaagct atccaggggc agataaagaa attgcaagtg
     3721 agattgacta tagcatagta aaaggaacag ttttattcga cttgtaccaa agaattatgg
     3781 atttagtttt atctataata ggacttgtga taggtttacc tttaatagca atatttggaa
     3841 ttcttattaa aatagaggac aaaggaccaa taacttataa gcaagaaaga ctaggaaaat
     3901 gcgggagaag attctatata tataaattga gatctatgag aacagacgca gaaaaatttg
     3961 gcgcacaatg ggctgaaaaa gatgatccta gaataactaa ggttggaaag tttattagga
     4021 aaactagaat tgatgagatt ccacagctgt ttaatatatt aaagggggac atgggcttaa
     4081 taggccctag accagagaga ccgaacttta ctgttcaatt taatgaggaa atacctggat
     4141 ttatcaacag gctcgctata aaacctgggc ttacaggttg ggcacaagta aatggtggat
     4201 acgaaatcac tcctgaagaa aaacttaaag aagatattta ctatataaaa aataggagta
     4261 tattacttga ctttaagata ctctttaaaa ctgttaaagt agtattgaca ggagacggag
     4321 ctagataatt ttaaaatatt agattactaa tcaatgaaaa agctctttaa aaagagcttt
     4381 tttattgtca aaaaatacaa aaaagaaaag gaatgagaac ttatgattaa aaaaatttct
     4441 actatattat cgttagtttt gttaatctct atttctagta cgataggggt atttgcagat
     4501 gcaaatccca aaagagagtt gatagaaggg agtataccag agatttcgac agaattaaat
     4561 aaaagagcat ttaaggattc taaagaagta attcttgtaa atgaagagtc aattgtagat
     4621 agtataagtg caacaccttt agcatatgca aaaaatgctc caatagttgt aactaagagt
     4681 aaaaatcttg gtagagtaac aagaaattat ctaaaagaac taggtccaga gaaggttacg
     4741 atagtaggtg gtttaaaggc agtatctaaa gatgctgaac gtaatataga aaaaatggga
     4801 atgaaagtag aaagaataag agggaaagac agatatgata catctttaaa gatagctaga
     4861 gaaatgtata gaacagtagg atttgatgaa gcatttttac ttagctcaac aacaggatta
     4921 gagaacgcca tatctgtata ttcttatgcc gctaaaagtg gaatgccaat aatatgggct
     4981 aaagatgaag ggtttgagga acaaattgat ttcttaaaag gcaaaaatct taaaaaaata
     5041 tatgcattag gtgattcaaa agaatttatt gcagagattg attctaattt aaaaaatata
     5101 gaaggaataa agcaaataaa taagtcaagt acaaatgttg atttaataaa gaagttttat
     5161 gatgaaaaag atataaagaa aatctatact gctagattag actttggtag cagatctgat
     5221 gtaaacgaat atatttcttt gggagtagta tcagcaaaag aaaatatgcc aatactgatt
     5281 tgtagtgata acttaagtcg tgcacaagat aaattcttga aagatagcaa tataaatgat
     5341 gtagttgaag ttgggtatac agtaggtgat tatagtctat ttaggagcat atttaatcta
     5401 acattcttat cttgtatagt attaatacta ttattactat tgattacatt tagggcactt
     5461 agatatgagt cgaaatagtt tttgatttat aaggaagctt ttcataggtt aaatttactt
     5521 aattagaata atgtttataa gcagttttaa aagttctact tttagagttt aaattagata
     5581 aggagaaaga agatgtcaaa aacagctaaa gcagcattgt ggattatggc agccactatg
     5641 ttttcaaaag tattaggttt ccttagagaa cttgtacttg caaatttcta tgggacaggt
     5701 atgtatgcag acgtatttgt attaacatta aatatacctg gtttaatcat agcagtcata
     5761 ggctctgcag ttgctacaac ttatatacct atgtactttg agacaaagaa aagactcgga
     5821 gatgaaggtg ccttaaaatt tactaataat gttttaaata tatgctatat aatggctata
     5881 gtaatagcta ttattgggct tttatttaca gagcaatttg ttacagtatt tgcagcagga
     5941 tttagaaacg accctgctaa gttccaagca gcaatattat ttactaaaat aatgatttca
     6001 ggagttttat tcctgagtgg aagtaaaata tttagttcgt ttttacaggt gaatgacagt
     6061 tttgtaattc ctgggcttat aggaatccca tataatatta taataatagc agcaatagca
     6121 ctaagtgcag gtaaaaacgt atggatacta ccagcaggag cactattggc tatggcgagt
     6181 caactattat ttcaactgcc atttgcattt aagaagtcct acaagtataa gccatatata
     6241 aatttaaagg atgagtctat aaaagaatta gtcaacctag tattacctat gttggtagga
     6301 gtagctgttg gacagttaaa tatatttgtt gacagattat tggcaaccac tttgggtaat
     6361 ggaaagttgt ctgctcttaa ctatgcaaat aggctaaatg agtttgttat ggcattattt
     6421 gttacatcta taataacagt tatatatcct aaactagcaa aaatgtctgg taaagataat
     6481 aaagaaggat ttataagtac tattgtaaaa tcttcaaatt gtattatatt ggtggtgctt
     6541 cctatatcta taggagctat tatattagca gagcctcttg ttaggatatt attccaaaga
     6601 ggtaaatttg atgcgttatc aacagacctt acatctatag cgcttagatt atattcacta
     6661 ggtttattgg cttgtggagt aagagatgtc ttatataggg cattttactc tctttcagat
     6721 acaaaaacgc caatgataaa tggaagtata gctttaataa taaatatagt tcttaattta
     6781 atattgataa gaccattggg tcatgcaggt attgctatat caactagtac atccaacata
     6841 attacagtta tattattatt tatatctctt aaaaagaaaa atggatattt tggaggggat
     6901 aaaattataa agactggtct aaaaagtttg gtagcatctg gtgtgatggc agtagctact
     6961 ttattgatat ataataatct atatgcattt atgggttcag gaacaattaa agaaattata
     7021 tcagttggag ctggagtatt aggtggagct tctgtatata ctgtattgat agttttattt
     7081 aaggtagaag agatggattt agcttttgaa tttttaagaa aaggaaaaca aaaactactt
     7141 agaagataga taattacctt gaaattttaa attagagtca gaaaggatga aaatatggat
     7201 tataagaata attatgagat gtggttaaat tctccttatt ttgatgaaca aacgaaaaat
     7261 gagctattaa gtataaaaga tgatgaaaaa gaaatacaag atagattcta taaaaattta
     7321 gagtttggaa caggtggttt aagaggtata ataggagcgg gaactaatag aatcaatatt
     7381 tatactgtta gacgtgcgac actgggcgtt ttaaattata tcatgaaaac tcaaggagaa
     7441 gaaggtaaac aaaagggaat agttatagca catgatagta gatacatgtc tagggagttt
     7501 tgtatagaag tagcaaagac tttaagtgct tatggtgtaa aggcttatat ttttgaagaa
     7561 ttaaagccta caccagaact ttcttttgct gttagatatt taaagtgtgc tatgggaata
     7621 gtaataacag caagtcataa tcctaaagaa tacaatggat ataaagtata tgactcagat
     7681 ggtggtcaaa tctgtataga tatggcaaat gatataatag cagaagttaa taagattgat
     7741 gattacagta ttattaaaag tatagatttt gaagaagctt tatctaaaaa tttaataact
     7801 atattagata atgaagtaga tgatgagttt ataaaagctg ttaagaagca agttttaaga
     7861 caaaatataa tagatgaatg tgggaaaaaa ttaaaaataa tatatacacc tattcatggt
     7921 acaggaaata agccagtaag aaaagtctta aatgaatgtg gttttgaaaa tgtaatggta
     7981 gttaaggagc aagaattgcc agattctaat ttttcaacag taaattatcc taatcctgaa
     8041 gaaaagtcag tgtttaatat agctattgaa atggcaaaga ataatggcac tgatttgata
     8101 ataggaacag accctgattg tgatagagta ggtatcgttg taaaagattc aagtggtgaa
     8161 tatgtagtct taaatggaaa tcaagtcggt tcacttttag ttagatatat attagagagt
     8221 ttagttgaag aaaataaact tcctaaaaac aatcctacaa taataaaaac tatagttaca
     8281 tcagaactag gtgcaaaaat agcaaaggct tataatgtag attgtttaaa tactttaaca
     8341 ggatttaaat ttataggaga aaaaataaaa gcgtttgaag aaagtaatga tagaagtttt
     8401 ataatgggat atgaggaaag ctatggttac ttaattggaa ctcatgctag agataaagat
     8461 ggtgttgtat cttcacttat gatatgtgaa atggcagcat actattcttc aaaaggtatg
     8521 aacttgtatg aagctttgat agatacatat aataaatttg gatactacaa agaggactta
     8581 aagtcagtaa ctttaaaagg catagatgga ataaaaaaaa taaaagagat gatgctttac
     8641 tttagaagtg ttaaaataga taatgtggct gatgtaaaag tagataaaat tttagactat
     8701 aaagatggtg ttgatgattt acctaagtca gatgtactta aatttttact tgaagatggc
     8761 tcttggatag ctataagacc ttcaggtaca gaacctaaaa ttaaatttta ctttggagca
     8821 aattcagaca atcaagaaga tgtagaattt aagttgaaca atttaatatc ttatatatta
     8881 aatgtagtgg attctatata aaaagctaag gggagataaa taatgaaagt atacaatgtc
     8941 ataatggctg gaggaggagg aactcgtttc tggccactta gtagacaaga agtacctaaa
     9001 cagcttataa atttaagtgg agaagatgct ttaataaatg aaactataaa cagaatagat
     9061 tctctagcaa aaaaagatga tttatttata gtaaccaatg agaagcaatt ggaagcttta
     9121 aaggatatag taaaagataa atgtttggat agtaatatat tgccagagcc atgtgccaga
     9181 aatacagcag cagctatagg ctttgcagca tttaacataa tgaaaaaata tggtgatggt
     9241 gttatgtgtg tatatccagc tgaccattat ataaaagatg aaaaagaatt taaatctatt
     9301 ttggaaaaag ctatctatat agcagaaaat aatgataaac tagtaactat tgggataact
     9361 cctacatttc catcaacagg atatggatac ataaatttta atagagaaaa cacgatagaa
     9421 gatgttgcat atgaggtagt ggagtttgta gaaaaaccaa actatgaaat tgctaaagaa
     9481 tatgtaaact ctaaaaagta tgtatggaat agtggaatgt tcgtatggaa ggtatctaaa
     9541 atattagaag attttaagag atacttgcca aaagtatatg aaaaattaga agatataagt
     9601 aaatacttag gaacaaaaga agaaatggaa aaaataaaag aaatataccc aactatacaa
     9661 tcaatctcta tagattatgg tattatggaa agaagtaatg atgttatagt agttcctggt
     9721 gattttggat ggaatgatgt tggttcttgg gattctctag gtgcaatata tccaactgat
     9781 gatgaaggta acatcaaaag aggtgaaaat attactatag atactaaaaa ttcaattata
     9841 tattcagatg acaaattaat atcgacaata ggtattagtg atttgatagt agtatctaca
     9901 aatgatgcag ttatggtttg tagaaaagat aaagctcaag atgtcaaaaa aatagtagag
     9961 cagttaaaag aagaagatag acaagaatat atgtaggagg tgttcatttg attcctaaaa
    10021 aaatacatta tgtatggttt ggtggtccaa aaggaaatat agaaaatata tgtataaatt
    10081 cttggaaaga aaagcttcca gaatatgaga tagtagagtg gaatgaaaaa aactttgata
    10141 tagagaaaga aataaaagga aataagtttt tggaagaatg ttataaaaga aaactttggg
    10201 cattcatatc tgattataca agaataaaag tactctatga acaaggtgga gtttatatgg
    10261 atacagatat gcaaatatta aaggatataa ctcctctttt agaaaataat aggttaatct
    10321 gtgggtatga agatgataga gagtatataa atggtgctat aataggtgta gaaaaaggac
    10381 atcctttttt aaaagactta ttggagtatt atgaaaaaga agtacttact tcttcattgt
    10441 ttacaatacc aaagataatg actcatctta tggaaaagaa ttataagaaa attgacccaa
    10501 ataattatga agaaggaata cgtgtttacg acaaagaata tttttatcct tttggattta
    10561 aagaagactt tacaccagaa tgtataacag aaaacacttt tgggatacat tggtggggaa
    10621 aaagttgggc taaaaagaga aattatttct tagaaagcaa acatttaaca ggtgtaaata
    10681 agatatggaa gtgttgtaaa atatttgcaa gtaatacttt acgaagctaa aagggagaaa
    10741 gtaaaatgaa gactttaaat gatgatagaa atattatgat tagaaaatat ctttatatat
    10801 ttgttttgtt tatcatatta cttagaaagt atatgatatc atttattgac ccaaatatgg
    10861 atatagggat gattaaatca gcgttatttt attcttcaat aggaatacta atgctacttt
    10921 ttttatttga taagagaaaa agtataacag aaatggtact agttggagtt tgtgtcttac
    10981 tttatttatt aaatagggaa ggagctatat tattaatcgt tttattagct gtatcagcta
    11041 agcaaataga tgataaattt atagtt
//
LOCUS       DAEPKC010000116        10814 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.117, whole genome shotgun sequence.
ACCESSION   DAEPKC010000116 DAEPKC010000000
VERSION     DAEPKC010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10814)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10814)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10814
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.117"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            336..560
                     /locus_tag="KR294_003245"
     CDS             336..560
                     /locus_tag="KR294_003245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241300.1"
                     /translation="MIIKLTKDNFNFRFKQYEGMFFHAEVVEGMESIRYKITKDKEGT
                     ELKEFGSTHIKDNMIYVPQVEAYIDLNSIK"
     gene            613..1137
                     /locus_tag="KR294_003246"
     CDS             613..1137
                     /locus_tag="KR294_003246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH0241301.1"
                     /translation="MSKPIDITIRPIRREDAQAFNEIRRTYSVMRNTLALMSDRVDKT
                     EAMLASLGENDYMFVAETNNNGEKDVIGFAGLHVNSSPRLRHSAEIGISVAENYQGRG
                     VGKKLMEQLLDIADNWIMLTRVGLEVIVDNEKGLNLYKKLGFEIEGTKKYAVIRDGKF
                     EDVYIMGRYNKNLI"
     gene            complement(1242..1388)
                     /locus_tag="KR294_003247"
     CDS             complement(1242..1388)
                     /locus_tag="KR294_003247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241302.1"
                     /translation="MDMDLLFKIVFAIVAIGVSVKIIKTVASLAFKIALILLIILFVY
                     RMFL"
     gene            complement(1527..2453)
                     /locus_tag="KR294_003248"
     CDS             complement(1527..2453)
                     /locus_tag="KR294_003248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HBH0241303.1"
                     /translation="MNFSNIFIQVAVLFIIILVGYFVRKFNLLDDHCTSKLSTLTMTV
                     FLPSMIISSMQINFDSKMIQKILLLLFTSLIMYIVSIIIAFLLKYILKCNDKKDLGIY
                     QYIVVFSNVAFMGYPVIEAVLGHEAIFYTAIFNLPFNLFSFTLGIYLLSKGSTSRGFS
                     IKSLISPATIAIVIGLFLFVTGLRLPQFINEPLEMLGSITTPISMIIIGSLLANSSAL
                     DCFVNKKLYIVTFIRLLVLPVIVYFILKGWINDKMILAIPVVISSMPAAANTAIMANQ
                     YDSNITLASQCVFFTTLFSVISIPFISILLLS"
     gene            2643..4514
                     /locus_tag="KR294_003249"
     CDS             2643..4514
                     /locus_tag="KR294_003249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sel1 repeat family protein"
                     /protein_id="HBH0241304.1"
                     /translation="MKNTKFSIKKIKNISNDPKVVHTKGALLEKMGKMESAIELYKSA
                     ALDNYVKSQYTLGNIYESKKQFKEAEKWYSMAYKSGSEDAAFDLGNMYYKLDGYEYAI
                     YWYEKIANLGYLQAQNNLGVCHFKMKDFVRCEKWLKTAADKNLGKACFNLGVLYTFLE
                     KDDEAYEYYKKGSVLLDDDAKYNLAILNGKKKDNKSTVSLYKQLYKSGHMKGCFNLGM
                     IMEINDNLEDAEKYYKKSADRDDVKSEYRLAYVYDRKEELGDAIYYYEKAIEKNHTLS
                     KYRLANLYNRENEIEKAKTYYKMAAEDDITEAKNNLAGIYFEEKDYENAIKYYEDAIA
                     VGCKSSLENLGDLYYQNQDIEKAISYYSRIPNNVSCQIKLGNIYEDLNNIEEAISWYK
                     KASENGDTRSSYRLGCIYESLGNTKNARKYFEMASSKNHMNARIHLGRIYFREGKLEE
                     SKMMFDTPANENNVYAQHMVGLIYDMFYKDYVNSKFWYEKARAQGCVESIYNLGQIYL
                     KLNDDAEAEKYYKEGIKYGSKKCEYMLAGLYYKKSLDMYISLANEEYDNCEEIVEGFP
                     NLNIDFDEVLIPPFKLQEEVIDEEEYVPIYILNIKESLDSMLEGLETEMIIDEEHDS"
     gene            complement(4606..5541)
                     /locus_tag="KR294_003250"
     CDS             complement(4606..5541)
                     /locus_tag="KR294_003250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HBH0241305.1"
                     /translation="MIRYYKTIDSKLEKLSFFEDGCWINLVEPNHSEINEISNLLNID
                     VESIESALDEEERSRIDVEDNHTLILIDIPVDESDSNSSHYTTIPLGIILTEEAIVTV
                     CDAQTKILNDFIVGHIKDFFTFKKTRFLLQILHKNAAYYLHYLRKINKMTIIIEREIY
                     KSMKNKELVQLLELEKSLVYFSTSLKSNELVLNKMVRTAGIKKYPDDEDLLEDVIVEN
                     RQALDMAKIYGDILSRIMDAFSAIISNNQNNVMQILTVVTLIFSIPTIISGFFGMNVI
                     NMPFSNNPNGFWIILLITSIICIVITFFMSRNKLL"
     gene            6061..6573
                     /locus_tag="KR294_003251"
     CDS             6061..6573
                     /locus_tag="KR294_003251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HBH0241306.1"
                     /translation="MSDFKEILAEEIKNNPFGLIGKDWTLITAENEGKVNTMTASWGG
                     LGVMWGKDVAFVVIRPQRYTKEFIDNTDKFSLTFFDEDFRKELSYCGKVSGREEDKIS
                     QIGFNIEHLNDTPYFKEAKMAIICKKMYSQKLEPQCFIAEGIDGRWYPQKDYHTLYIA
                     EITNVLVKED"
     gene            complement(6728..7789)
                     /locus_tag="KR294_003252"
     CDS             complement(6728..7789)
                     /locus_tag="KR294_003252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015617764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitronate monooxygenase"
                     /protein_id="HBH0241307.1"
                     /translation="MIIKELIIRDLVAKVPIIQGGMGVGISRSSLAGAVAKLGGVGVI
                     SGVQIGYDEEDFETNTINANLRAIKKHISKAKEISNGGIIGINFMVAMKEYETYVKEA
                     VKAGVDLIISGAGLPNKLPSLVKGSNVKIAPIVSTAKAANVILKMWDRKEKTTADLIV
                     VEGPKAGGHLGYSNEELDNIDSIDYDKEFVEILKVANTYGEKFGRNIPVVAAGGITSS
                     SDVKKYIDMGASGVQVGTRFVATYECDAHENFKMAYINASEEDVHIVKSPVGLPGRAI
                     RNKFIEEVKINRPEIKKCYNCLIPCNPKETPYCISQALINAVKGDVENSLLFCGNDAY
                     KIDKLSTVEDVINELISEL"
     gene            complement(7913..8806)
                     /locus_tag="KR294_003253"
     CDS             complement(7913..8806)
                     /locus_tag="KR294_003253"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HBH0241308.1"
                     /translation="MLEIIVPATSANIGPGFDCLGIALNIYNKFYVEEIESGLEIEGC
                     EDAYKNENNLVYTSMKYFFDRVKPEKIPAGIKIKIQSEVPICRGLGSSASCIVAGVIA
                     ANALSGANLDKNQLLNIASEIEGHPDNVAPAILGNMIVSVTDNENIHYDIIKIPEELK
                     FCAMIPNFKLSTEKARGVLPKEIPYSDGVFNVSRVALLISALLNKNFDLLKVACQDKL
                     HQDYRGTLIENYNDIVEKSEQLNSIGVFLSGAGPTIMSLIKENDDSFVDNMKNYLQKL
                     KSDWEIKELCCDSNGAVLNII"
     gene            complement(8816..10297)
                     /locus_tag="KR294_003254"
     CDS             complement(8816..10297)
                     /locus_tag="KR294_003254"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HBH0241309.1"
                     /translation="MYYSSTRGTEEKVTASQAIIKGISNDGGLYVPSEFPNVKNELIN
                     LVNLTYSQIAFFVLSKFLCDFTEDEIKNCIENAYDEKFDCSSIAPLNKVNDTYFLELY
                     HGPTLAFKDMALTIMPHLLKTSIKKDNLEKDVVILTATSGDTGKAALEGFKDIDKIKI
                     IVFFPEDGVSPVQKLQMKTQTGKNTYVVGIKGNFDDAQSGVKKIFSDKEFNQKLLDNN
                     YILSSANSINIGRLLPQVAYYFYSYMKLVSNSDINLNDKINFVVPTGNFGNILAGYYA
                     KQMGLPINKLICASNDNNVLYDFFKTGVYDKNRTLKLTTSPSMDILISSNLERLLFEI
                     SNRNTDIVNKLLSDLSDKGVYKISDDMEKNLASFYGEYSNEEEVKSTINNVFKNYNYL
                     IDTHTAVAYNCYEKYKKETSDNTKTVIVSTASPFKFSEDVLKSIDCDFKDLDDFAIID
                     RLSSISKIDIPKPIKNLKNAEILHKDIYEKDELKLAIKKFLKV"
     misc_binding    complement(10405..10636)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
BASE COUNT         4095 a         1377 c         1532 g         3810 t
ORIGIN      
        1 tcaatatttg tacaattatt ttatctatga attgggagta atatttttca acaatatttg
       61 gaactttgct ggctataaaa tttaaaagca aagcaatagg aaagagaatt aaagaaaaat
      121 attttgtttt tttgctcata tttcacctca catacattag tttatataaa catattatat
      181 atcaattgaa gaaagattgt aaaataagta taaatatatc tatttataac tttatactaa
      241 ataaatgata agttataata tattaatatg aataagcagt atatatacaa ctaataataa
      301 gaaaaatatc aattatataa ggagtagata aaaatatgat aataaaactt actaaagaca
      361 attttaattt tagatttaaa caatatgaag gtatgttttt tcatgctgaa gtagttgaag
      421 gtatggaatc cattagatat aaaataacta aggataaaga aggtacagaa ttaaaagaat
      481 ttggaagtac acatataaaa gataatatga tatatgtacc tcaggtagaa gcatacatag
      541 atttgaacag tataaaataa agatgtaaaa ttttaattaa aaataaagat tatgtttgag
      601 ggggaatcca atatgagtaa gcctatagat ataacaataa gacctataag aagagaagat
      661 gcacaagctt ttaatgaaat tagaagaaca tacagtgtta tgagaaatac tttggcatta
      721 atgagtgaca gagtcgataa aactgaagct atgttagctt ctttgggaga aaatgattat
      781 atgtttgtag ctgaaactaa taataatgga gaaaaagatg taataggttt tgctgggtta
      841 catgtaaatt cttctccacg attgagacat agcgcagaaa taggaataag tgttgcagag
      901 aattatcagg gaagaggagt aggtaagaag cttatggaac aacttttaga tatagcagat
      961 aattggatta tgttaactag agtaggatta gaagtaattg tggataatga aaagggatta
     1021 aatttatata aaaagctagg ttttgaaata gagggaacta aaaaatatgc tgtaatcaga
     1081 gatggaaaat ttgaagatgt ttatattatg ggaagatata ataaaaattt aatttaaata
     1141 agctaataga gaagtaaaat agagtgtctt taataaaaaa tttacattaa agataatcta
     1201 ttttacttct ctattgtgtt aaaaaactta tttttaaatg tttacaaaaa cattctatat
     1261 acaaataaaa ttattagcaa tatcaacgct attttaaaag ctaaactagc aacagtttta
     1321 atgattttta cagaaacacc tatagcaact atagcaaata ctattttaaa gagtaaatcc
     1381 atatccatat ttaagcctcc tattctataa tacatataga tattattgac aaatatctag
     1441 gaaaaaattc catcaatata ctacaataaa atgtttatat ttgtaattta ttgaatatgt
     1501 tattatataa tacataaaaa aataaatcaa gataagagta aaatacttat aaaaggtata
     1561 gatataactg aaaatagtgt tgtaaaaaac acacattgtg aagctagtgt tatattggag
     1621 tcatattgat tagccattat agcagtattt gcagcagcag gcattgaaga aattactact
     1681 ggtatagcta aaatcatctt atcatttatc catcctttta gaataaaata cacaatcaca
     1741 ggaagtacca ataatcttat aaaagtgact atatataatt ttttgttgac aaaacaatcg
     1801 agagctgaag aattagcaag taagcttcca atgataatca tggatattgg tgtagttata
     1861 cttcccaaca tctcaagtgg ctcgtttata aattggggta acctaagtcc tgttacaaat
     1921 aaaaaaagtc caataacaat agctattgta gcagggctta taagtgattt tattgaaaaa
     1981 cctctacttg tactgccttt agataaaaga taaattccta aagtgaaaga aaataagtta
     2041 aaaggcaaat tgaatattgc agtatagaat attgcttcat gacctaaaac tgcttcaatt
     2101 acaggataac ccataaaagc aacatttgaa aaaacaacta tatactggta tattcccaaa
     2161 tcttttttat cattacattt taaaatgtat ttcaataaaa atgcaattat aattgaaact
     2221 atatacataa tcaaagatgt aaataataac aatagtattt tttgtatcat tttactatca
     2281 aagttaattt gcatggagct aattatcatt gatggtaaaa aaactgtcat tgtcaaagtt
     2341 gaaagcttag atgtgcagtg gtcatctaat aagttgaatt ttctgacaaa atatccaact
     2401 aaaataatta taaataaaac tgcaacttgg ataaaaatat tgctgaaatt cataaaatgt
     2461 cccccctata tatacattat ataccaatta cataataaaa tctaatgatt ataaaattta
     2521 aaatttaatg ttacaatata gtgacaaaag gtaaaaattc aatattatag cattaattgt
     2581 agattataat gtataataat gtttgagaga atatatttta taaaatgggt aggtagcgaa
     2641 taatgaaaaa tacaaaattt tctataaaaa aaataaaaaa tatatctaat gacccgaaag
     2701 tcgtacatac taagggtgcc ctccttgaaa agatgggtaa gatggaaagc gcaatagagt
     2761 tgtataagag tgctgcattg gataattacg taaaatctca atatacttta ggaaatatat
     2821 atgaaagtaa aaaacaattt aaagaagcag aaaagtggta ttcaatggca tataaaagtg
     2881 gaagtgaaga tgctgctttt gatttaggta atatgtacta taagttagat ggctatgaat
     2941 atgctatata ttggtatgaa aagatagcaa atttaggtta tttacaagca caaaataatt
     3001 taggtgtatg ccattttaaa atgaaagatt ttgtaaggtg tgaaaaatgg ttaaaaacag
     3061 cagcagacaa gaatttaggt aaagcttgtt ttaatttagg ggtattatat acttttttgg
     3121 agaaagatga tgaagcatat gaatactata aaaaaggttc tgtgctttta gatgatgatg
     3181 caaaatataa tttagcaata ttaaatggaa aaaagaaaga taataaatca acagtaagtt
     3241 tatataaaca gttgtacaag tcaggtcata tgaaaggttg ctttaacttg ggtatgatta
     3301 tggaaataaa tgataattta gaagatgcag agaagtatta taaaaagagt gctgatagag
     3361 atgatgtgaa gtctgagtat aggcttgcat atgtatatga tagaaaagaa gagctgggag
     3421 atgcaattta ttattatgag aaagcaatag aaaaaaatca tacactttct aagtatagac
     3481 ttgctaattt atataataga gaaaatgaga tagagaaggc aaaaacttat tataaaatgg
     3541 ctgctgaaga tgatataaca gaagcaaaaa ataatctggc aggtatatat tttgaagaaa
     3601 aagattatga aaatgctatt aaatattatg aggatgctat agctgttgga tgcaaaagtt
     3661 cccttgaaaa tctaggggat ttatattatc agaatcaaga tatagaaaaa gcgatttcgt
     3721 attattcgag gattccaaat aatgtatctt gtcaaatcaa attaggaaat atctatgaag
     3781 atttaaataa tattgaagaa gcaataagtt ggtataagaa agcatctgaa aatggagata
     3841 cgaggtctag ttatagattg gggtgtatat atgagagctt aggaaataca aaaaatgcta
     3901 gaaagtattt tgaaatggca agtagcaaaa accatatgaa tgctcgtata catctaggta
     3961 gaatttattt tagagaaggt aaattggaag agtctaaaat gatgtttgat acacctgcca
     4021 atgaaaataa tgtgtatgct caacatatgg taggattaat ttatgatatg ttctataaag
     4081 attatgtaaa ttctaaattt tggtatgaaa aggctagagc acaaggttgt gttgaatcaa
     4141 tatataattt aggtcaaatt tatttaaaat taaatgatga cgcagaagct gagaaatatt
     4201 ataaagaagg tattaaatat ggaagtaaga agtgtgagta tatgcttgca ggtctttatt
     4261 ataaaaagag cctagatatg tacatttctt tagcaaatga agagtacgat aattgtgaag
     4321 agatagtaga aggctttcca aatttaaata tagactttga tgaagtatta attcctccat
     4381 ttaagttgca agaagaggta atagatgaag aagagtatgt accaatttat atactaaata
     4441 taaaagaaag tttagattca atgctagaag ggcttgaaac tgaaatgatt atagatgaag
     4501 aacatgatag ttaaaaagta ttataagatt atatagattt aaatatataa aagccattag
     4561 gataaatgta aatcaattaa ttctaatggc ttttttatta atattttata atagcttatt
     4621 tcttgacatg aaaaatgtaa tcactataca tattatagag gtaataagaa gtattatcca
     4681 aaatccgttt gggttattag aaaatggcat gttgatgaca ttcataccaa agaatcctga
     4741 tattattgta ggtattgaga aaattagtgt aactactgtt aaaatttgca taacattatt
     4801 ctgattatta cttataattg cactgaaagc atccataatt ctactcaata tatctccata
     4861 tattttagcc atatcaagag cctgtctatt ttcaactata acatcttcta ataggtcttc
     4921 atcatctgga tacttcttta taccagcagt tctaaccatt ttgtttaaaa caagttcatt
     4981 agattttagt gaggtagaga agtataccaa agatttttct aattccaata attgaaccaa
     5041 ttctttgttt ttcattgatt tgtaaatttc tcgctctatt atgattgtca ttttatttat
     5101 ttttcttaag taatgcaagt aataagctgc atttttgtga agaatttgaa gcaaaaagcg
     5161 agtcttttta aacgtaaaaa aatctttaat atgaccaact ataaagtcat ttaaaatctt
     5221 agtttgtgca tcacaaactg ttacaatagc ttcttcagtt agtataatac ctaagggtat
     5281 tgtagtataa tgagaagaat tagagtcact ttcgtctact ggtatatcta taagtataag
     5341 agtatgattg tcttcaacat ctattcttga gcgttcttct tcatctagtg cagattctat
     5401 gctttctaca tctatattta ataaattaga aatttcgttg atttcactat gattaggttc
     5461 aacaagattt atccaacagc catcttcaaa aaaactaagt ttctctaatt ttgaatctat
     5521 agttttgtaa tatcttatca tggcaacaca tcctttattc agttttatat aaatctcatc
     5581 atttaatagt atctattaat taactaattt atataactga atatatgtat tagttttgat
     5641 tttagatatt attaagtgat gaaaatgtaa aaaattctct ccgcaacgga ctagtatcca
     5701 ttgcccatca ctctccttat ttattatttt atatatagct atttatgaaa tgcgtatttt
     5761 aagcactctt taatataata ccttttccag gtatataaat caagttttga tttgattaaa
     5821 taatattttt accataattt acacataaag tatataagtt atatttaatt tgagtaaaga
     5881 atatatatat tctgagtgaa attattaaat atattaaaaa ataagagtgt atatatatat
     5941 ttacttattt gcaataatat atttaaaaaa gtattttatt ttcaaaacta gacttcattt
     6001 ataatttatc atgaaaataa aaggaatata aatataagag aatgagaggt tattagagat
     6061 atgagtgatt ttaaagaaat tttggcagaa gagattaaaa ataatccatt tggattgata
     6121 ggtaaagatt ggacacttat aacagcagaa aatgaaggta aagtgaatac aatgactgct
     6181 agctggggag ggcttggagt tatgtgggga aaagatgttg cttttgtagt aataagacca
     6241 cagcgttata ctaaggaatt tatagataat acagataaat tttctcttac attttttgat
     6301 gaagattttc gtaaagagct ttcatattgt ggaaaagtat ctggtagaga agaggataag
     6361 atatcacaga ttggatttaa tatagaacac ttaaatgata caccttattt taaggaagct
     6421 aaaatggcta ttatatgcaa aaaaatgtat agtcagaaac ttgaacccca atgttttatt
     6481 gctgaaggta tagatggaag atggtatcca caaaaagatt atcatacttt atatatagct
     6541 gaaataacca atgtacttgt aaaagaagat tagttataag ggttaatact atctctaatt
     6601 aaattaaaat ttcaataaaa ggaaattgac acaaaaaagc taaggacata aatatgttta
     6661 taaagattaa taaataacgt atttaaactc cttagcttga taaaatttta atttagtttt
     6721 ctttaaatta taattcagaa atcaattcat tgataacatc ttcaacagta cttaatttat
     6781 caattttata ggcatcattt ccacaaaata aaagtgaatt ttcaacatct cctttaactg
     6841 cattgattag agcttgagaa atacagtaag gagtttcttt tggattacaa ggaatcaaac
     6901 aattatagca cttctttatt tctggacgat ttattttaac ttcttctata aatttgtttc
     6961 ttatggcacg tccaggaaga cctacaggac ttttaactat atgaacatct tcttcactag
     7021 catttatgta tgccatttta aagttctcat gggcatcaca ttcgtaagta gcaacaaatc
     7081 ttgtaccaac ttgtacacca cttgcaccca tatctatata ttttttaaca tcactactag
     7141 aagttatacc accagcagca actactggta tgtttctacc aaatttttct ccataagtat
     7201 ttgcaacctt taaaatttca acaaattcct tatcatagtc tatagaatct atgttatcaa
     7261 gttcctcgtt agagtatcca aggtgaccac cagcttttgg accttcaaca actattaagt
     7321 cagcagtagt tttctctttt ctatcccaca tttttaaaat tacattagca gcttttgcag
     7381 ttgaaactat gggtgctatt tttacattac ttccctttac taatgatggt agcttattag
     7441 gtaatccagc tccagatatt ataaggtcta caccagcttt aacagcttcc tttacgtatg
     7501 tttcatattc tttcatagct accataaaat taataccaat aataccacca tttgagattt
     7561 ctttggcctt agaaatatgt ttttttatag ctcttaaatt tgcatttata gtattagttt
     7621 caaaatcttc ctcatcatat ccaatttgaa ctccagaaat tacaccaaca ccaccaagct
     7681 tagcaactgc accagctagt gatgacctag atataccaac gcccattcca ccttgaatta
     7741 taggaacttt tgcaactaaa tctctaatta ttaactcttt tatgataatc cctcctcaat
     7801 gtaaacatgt ttaaagaact agattataat acttaatatt attacctagt cctaattatt
     7861 atactacaaa ttataataaa agagtagtta tattttgtat agaagacgat aattatatta
     7921 tatttaaaac agctccatta gaatcgcaac ataactcttt tatttcccaa tcagatttta
     7981 gtttttgtag gtaatttttc atattatcca caaaactatc atcattttct tttattaaag
     8041 acattatagt aggtccagct ccacttaaaa atactccaat actatttaat tgttcagatt
     8101 tttcaacaat atcattgtag ttctcaatta gagttcctct ataatcttga tgcaatttgt
     8161 cttgacaagc tactttaagt aggtcaaagt ttttgtttag taaggcagat attagtaaag
     8221 caactctact aacattgaat accccatcag aatatggtat ttcctttggt aaaacacctc
     8281 tagctttttc tgttgataac ttaaaattag gtatcattgc acaaaattta agttcttcag
     8341 gaatttttat aatatcataa tgtatattct cattatcagt aacagataca atcatatttc
     8401 ctaaaatagc aggagcaaca ttatctgggt gaccttctat ttctgaagct atatttagta
     8461 attgattttt atctaaatta gcacctgata gagcatttgc agctataact ccagctacta
     8521 tacaagaggc actactgcca agacctctac atataggtac ttcactttgg atttttattt
     8581 tgataccagc aggtattttt tctggtttaa ctctatcaaa aaagtacttc atagatgtat
     8641 aaactaagtt gttttcgttt ttgtaagcat cttcacaacc ttctatttca agaccacttt
     8701 caatttcttc aacataaaat ttattgtata tatttaacgc aattccaaga caatcaaatc
     8761 ctggacctat attagcactt gttgcaggaa ctataatctc taacataata atcacctata
     8821 cctttaagaa tttttttata gctagtttta attcatcttt ttcataaata tctttatgta
     8881 gtatttctgc atttttaaga tttttaatag gttttggaat atctatttta gaaatacttg
     8941 ataatctatc aattatagca aagtcatcaa ggtctttaaa atcacaatct atagacttta
     9001 gaacatcttc agaaaacttg aatggacttg cagtacttac aataacagtt tttgtgttat
     9061 cagaagtttc ttttttatat ttttcataac aattgtatgc aacagcagta tgagtatcta
     9121 tcaaataatt ataattttta aacacattgt ttatcgtgct tttaacttct tcttcatttg
     9181 aatattctcc atagaatgag gctaaatttt tttccatatc atcacttatt ttgtagactc
     9241 ctttatcact aaggtctgat aaaagcttat ttacaatatc agtatttcta tttgatattt
     9301 caaacagtaa tcgttctaaa ttacttgaaa ttaatatatc catagaagga gaagtagtta
     9361 atttcaatgt tctattttta tcatatacac cagttttaaa gaaatcataa agaacattat
     9421 tatcatttga tgcacatatt aatttgttta ttggaagacc catttgtttg gcataatatc
     9481 cagctagaat attaccaaaa ttaccagttg ggacaacaaa atttatttta tcatttaaat
     9541 ttatatcact attgctaact aatttcatat atgaataaaa atagtatgca acttgtggaa
     9601 gaagtcttcc tatattaatt gaatttgcag aagataatat ataattatta tccaatagtt
     9661 tttgattaaa ttctttatca gaaaaaatct tctttacacc tgattgtgca tcatcaaaat
     9721 ttccttttat accaactaca tatgtatttt ttccagtttg agttttcatt tgaagttttt
     9781 gtactgggct tacaccatct tctgggaaga atacaattat ctttatttta tctatatctt
     9841 taaatccctc aagtgcagct ttacctgtat ctccagatgt agcagtaaga atcacaacat
     9901 ctttctctaa attatctttc tttatagatg ttttaagaag atgaggcatt atagtaagtg
     9961 ccatatcttt aaatgctaaa gttggaccgt gatatagttc taagaaataa gtatcattta
    10021 ctttatttaa tggagctata ctactacaat caaacttttc atcatatgca ttttctatac
    10081 aatttttaat ttcatcttca gtaaaatcac ataaaaattt actaagtaca aaaaatgcta
    10141 tctgagaata cgttaaattt actaaattta taagttcatt ttttacattg ggaaattcac
    10201 ttggaacata aagaccacca tcatttgata ttccttttat tattgcttgt gatgcagtta
    10261 ctttttcttc ggtgcctctc gtacttgaat aatacatttt ttataatcct ccatatattt
    10321 taaattttta attagctaat taaattagat acagaatatt ttaaaaactg aatttaggta
    10381 ataaaaaaag accctcatcc ctaaaaaagg gacgagaatc tgtttcccgc ggttccaccc
    10441 aaattgattt taaaaaatcc acttgatact ttaacgcaag taataaaaac gtctattcct
    10501 actaaaatca ttaagataac ttcggataga agctcctagg tagttttcaa tccttctaat
    10561 tagggaaaca tttcagctag tagtttcctt ctctggtaat cgattcagat ttactcttcc
    10621 taatcaatgc ctttcaatat tcttaatatt attaattatt ctagtttata aaacagacaa
    10681 agtcaagtat taatataaaa atttggaaaa aatatttttt aaattgtaaa aaaattgtaa
    10741 tcaaattgag tattagaaaa atattttttt aactttttta aaagtttaaa aacctagatt
    10801 ttcatagtga tgaa
//
LOCUS       DAEPKC010000117        10338 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.118, whole genome shotgun sequence.
ACCESSION   DAEPKC010000117 DAEPKC010000000
VERSION     DAEPKC010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10338)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10338)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10338
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.118"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            204..983
                     /locus_tag="KR294_003255"
     CDS             204..983
                     /locus_tag="KR294_003255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HBH0241310.1"
                     /translation="MSYKKIAIITGANSGFGKEFLKLLINEEEITEIWAVARNKARLN
                     QLVDEFGSKVKIFSKDLSKIEEVKEIGTFLSKENVCIKYLINNAGFAKFCSYNDLSID
                     ESINMIDLNISAVVALGLICIPYMQKGSHIMNISSQASFQPLPYQNIYSSTKAFIRNY
                     TRALNVELKSKGINAIAVCPGWMSTNLFKRGIVVAEKGTKNFPGIVSPDIVAKKALKD
                     AKKNKDISVYGINTKSSHLLAKLLPQKMMMKVWLMQQHIKE"
     gene            complement(1293..2114)
                     /locus_tag="KR294_003256"
     CDS             complement(1293..2114)
                     /locus_tag="KR294_003256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002572585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallohydrolase"
                     /protein_id="HBH0241311.1"
                     /translation="MKLKIVGSGGMSIIPSSFCKCKICEEARQKGGRYERLGPSLYID
                     DIKMLIDTPEDIAVACNRQKISEVKHISISHHDPDHVKGIRIVEKIGCDFITGENNPI
                     GFYALPEVIEDINRTNLDCLKYYGNVINCISINETSHVKINNFDIDLINNNPDRNITF
                     YVIKENEKKVIYACCNPKPFTHSDMYFDADVLIISLVSDDGILNDGTKLKDTPFKDEI
                     FTLDEIVEIKNYYRIKKIIITHIDEIWGKSYGYYSELEKKLDNIYFAYDGMEIIV"
     gene            complement(2789..3607)
                     /locus_tag="KR294_003257"
     CDS             complement(2789..3607)
                     /locus_tag="KR294_003257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH0241312.1"
                     /translation="MFKIGDFSKLSKISIRMLRHYDEIGLLTPSHTNKTNGYRYYSAD
                     QLSTTNRIHALKDMGFGLYSIKEILTEYNDKESLIKYLNIHHSQVKEQLEDTQKKLLK
                     IETTIKRIGGNDIMKNYDVTIKNFAPKYMMTLRRVIPTYQDEGMLWHQVFLETKDQNV
                     QIEPPKYSKAVFYDTGYKEDYVDVEVQVAVSGKYKDTEHVKFKTVPSVTAATAIVNGN
                     FNQVADACEAIGNWISDNNYDVDGPMFNIYHVSPGNDSNPDNWVTEVCFPVKKK"
     gene            3775..4356
                     /locus_tag="KR294_003258"
     CDS             3775..4356
                     /locus_tag="KR294_003258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH0241313.1"
                     /translation="MKSNDKDARERIIEVTLNLLNEVDDIEEITVRKIAERANVGVGL
                     INYHFKTKDNLLSTAIGDVMSNIIAELYDDSVYTLRPIEDLKNLLKKLCDTGLHYEKV
                     LPFVLNQCITNGDMQAELDIVPMLRKIFGNKKDEMSLRIIALQIILPIQISALSTESF
                     QLYSGINIKNKYERDKFIDILIENIIGEDVDVR"
     gene            4353..4547
                     /locus_tag="KR294_003259"
     CDS             4353..4547
                     /locus_tag="KR294_003259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241314.1"
                     /translation="MKIITIGSSLITVLLFLSTMVCGFWIKNNKVTDASSIKFHMNSA
                     IFTGIFLLISTILLIIYIKK"
     gene            complement(4711..6453)
                     /locus_tag="KR294_003260"
     CDS             complement(4711..6453)
                     /locus_tag="KR294_003260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M3"
                     /protein_id="HBH0241315.1"
                     /translation="MVKSKKKIFVFLILIAVFIIFASYIRNYTNDTKKDSVRGTIPFE
                     KMEYKRPNIQSICENINKCNDKLLTAKTAKEQLNLFNEVDKIYQDFYSTLTIAKIRNN
                     IDSSDEFYSKEYKYLMSKSVDVDMSYKDFQDRFVTSKFSKELEKELGKDTFNYLKNIG
                     KLNSKEVEGLLKKEQDLVVKYEDLLAKSTVSIDGIEVDFEEALSRPNLSPEEYVKIYS
                     DYLKKYNPIFGNIFLELIQTRTEIASKQGFKNYIDYAYMNLNKDYSQEEAKKFRQDVK
                     DYIVPLYREISSKPSDSSIYIKVYKNRSFRKFDKVLEDISPKLKESFDYMKKYDLYDY
                     SSGKNKSPGGYTTYINKYKAPFLFNTWDNSFLGVTSFAHEFGHFYNYYNSINLNNKMQ
                     PSIDVCEVHSTSLEILFYKYFDDFFGKQSEAIKKEHLSIVLNTIIDACLYDEFQEIIY
                     KNPYMSLNDINKLFFDLEEEYGVSNNILREKNAPFWILVSHNFQVPFYYLSYGLASDV
                     SLQIWQLSQEDYRKAVDVYMDFLNQNTDAGFKDVVEKVNLQLPFQNGNLEEISSTLYD
                     YFGIDNPLELKNAS"
     gene            6882..8258
                     /locus_tag="KR294_003261"
     CDS             6882..8258
                     /locus_tag="KR294_003261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk family potassium uptake protein"
                     /protein_id="HBH0241316.1"
                     /translation="MKTIVRRLILYADGMRPTQIMVSGFAAIIVIGALLLTLPIASQS
                     GESIGLLNALFTATSAVCVTGLVMVDTATYWSLFGQIVIITLIQIGGLGFMTVATMFS
                     LMARKKIQLRERLLIQESLNQADLSGLVRLTRFVLIITITIEGIGALVLSTVFIPQFG
                     LSKGIWYSVFHAISAFCNAGFDLMGSVSGPFTSLNSYVNNFTVSMTVCALIVLGGLGF
                     PVVLDIVRKRRFSKLNVHSKVVLFSTATLIFVGALFIFLIEFNQKATMADLPLKGKVL
                     SAIFQSVTARTAGFNTLDLATLRESSVFVMIILMFIGASPASTGGGIKTTTLAVLIIT
                     VRSFLSGKSDIEAFERRLAPSTIKKSLGIFVISISAVIFGTLIISITQPNFTLVQSAF
                     EVTSALATVGSSLAGTPNLNALGKIIIIIFMFMGRVGSLTLFMAILSGGRRKSQPIRY
                     AEGKIMVG"
     gene            8545..9216
                     /locus_tag="KR294_003262"
     CDS             8545..9216
                     /locus_tag="KR294_003262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HBH0241317.1"
                     /translation="MKQYIVIGCGRFGSSVASTMHLLGHQVMAIDKNEDSVQSISDKV
                     THSLIVDVTDEQALRSLGLGNFDVAVVAIGSDIRASIMATLIAKEMGVELIICKAKDE
                     LQAKVLYKIGADRVVFPERDMGVRVAHNLVSDNILDHIELDPEYSIVEIVTPNSWVGK
                     TLIELELRARYEITVLAIKTGKNINVTPSPDEELTAGSILVIIGQNTSITAITSGNKG
                     IIRRR"
     gene            9405..10202
                     /locus_tag="KR294_003263"
     CDS             9405..10202
                     /locus_tag="KR294_003263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HBH0241318.1"
                     /translation="MITNINSKDNEKLKYTRALLKSKNRNKESKFIIEGYRIVMLALE
                     CMANLDYVFINEEFENKKEHVKLLEDLDKKNTKIYKTTNKNFKELVDTENTQGIIGVV
                     SFKKKKLSESINKKDKFVLILDRIQDPGNMGTIIRTADSAGVDAIIALKGCVDIYNPK
                     VIRSTMGSIFDVNIIDASQDETVDMLKSLDFNIVSSYLNTENFYDKIDYGSKVALVIG
                     NEANGINEELVSKSDILVKIPIYGKAESLNAAISSAILMYEIKKYLI"
BASE COUNT         3825 a         1247 c         1572 g         3694 t
ORIGIN      
        1 ataattaaca ctacttttta aatataatca ataccgattc tataatatta acactatttt
       61 ttatgctata taacaattat tgaaaatgat ataaatataa tatctcaaat aatatgaata
      121 taacatctga atagagggtg ttttatttgt aaaaaataag tttacagttt gagcgtataa
      181 acttatggta aaggagaata attatgagtt ataagaagat tgcaattata acgggtgcta
      241 atagtggttt tggtaaagag tttctaaagt tattaataaa tgaagaagaa ataacagaaa
      301 tatgggcagt tgcaagaaac aaggcgagat taaatcaatt agtagatgaa tttggaagta
      361 aggtaaaaat tttttcaaaa gatttatcaa aaatagaaga agtaaaagaa attggtacat
      421 ttttaagtaa agaaaatgta tgtataaaat accttataaa caatgctggt tttgcaaaat
      481 tctgttcata caatgattta agtatagatg aatctattaa tatgattgat ttaaatatta
      541 gtgctgttgt agcattggga cttatatgta ttccatatat gcaaaaggga agccatatca
      601 tgaatatttc ttcacaagca tcattccagc cattgccata tcaaaatatt tatagttcaa
      661 ctaaagcgtt tataagaaat tatacaagag cattaaatgt tgaacttaag agtaaaggga
      721 taaatgcaat tgctgtatgt ccaggttgga tgagtacaaa tctatttaag agaggtatag
      781 ttgtagctga aaaagggaca aaaaatttcc caggcatagt gtctccagac attgttgcca
      841 aaaaagcatt gaaggatgca aagaaaaata aggatatttc tgtgtatggt ataaatacaa
      901 aatccagtca tttattagca aaactattgc cacaaaaaat gatgatgaag gtttggttaa
      961 tgcaacaaca tattaaggaa taagagtttc ggtaattaag tatcagttgg agattcaatc
     1021 tgttatatat tatgagaagt tttgttgagc aaataataat tgtgacaaaa cggcttatct
     1081 agtgccgata agccgtctat aatgtatata aaatatattt ttgattttac tttatttaga
     1141 tattgaagta ttaaaatatg taggacttga aattttataa agataaatac tatgatattt
     1201 tgtaaaaact gagatatgtt gatattacat agtttaacta tactgttaaa ttgaagtttt
     1261 cttattttgc attatgctta ttacttaatg atttagacta taatttccat accatcatat
     1321 gcaaaataaa tgttatcaag tttcttttct aattcactgt aataaccata tgattttccc
     1381 catatttcgt caatatgtgt aatgataatc tttttaattc tataatagtt tttaatttca
     1441 acaatctcat ctaaagtaaa tatttcatct ttaaatggtg tgtctttaag ttttgtacca
     1501 tcatttaata taccatcatc agaaactaga cttattatta aaacatcagc atcaaagtac
     1561 atatcactat gagtaaatgg cttgggatta cagcaggcat atatgacttt tttttcattc
     1621 tctttgataa catagaaggt tatattcctg tctgggttat tgttaatcaa atcaatatca
     1681 aaattattta tctttacatg cgaagtttca ttaatagaaa tgcaatttat aacattacca
     1741 taatatttaa gacaatcgag attcgttcgg tttatatctt caattacttc aggaagcgca
     1801 taaaagccaa ttggattatt ttctcctgtg ataaagtcac atcctatttt ttcgacaatt
     1861 ctaataccct taacatggtc tgggtcatgg tgagaaattg aaatatgttt tacttccgat
     1921 attttttgtc tgttacaagc tactgcaata tcttcaggtg tgtctatcag catttttata
     1981 tcatcaatat ataaacttgg ccctaatcgt tcatatcttc cgcctttttg tctggcttct
     2041 tcacatattt tgcatttgca aaatgaactt ggaataattg acataccgcc actaccaaca
     2101 atttttaatt tcaaagttat tacaccacct tcttaaaata ttagattata taaataatct
     2161 acaatcacaa ctgattaaca aaattatgag ttaataaatt atatcacatg taaatatgaa
     2221 agaatagtat gaaattttta taaacatata ttaaatgttt ctcaatgaaa ttgactttgt
     2281 atatgaactg aatgacttat tcaatatgga taagacattt ttcttgtaat aagatatgat
     2341 tgtcctataa ggtttatgta attttgatat aatttgatat aatatattga ttaacaacat
     2401 acatgttatt ggtgagcata tttctataga atggaatata taatttttta tatttatcat
     2461 tgtattattg tctaaagaaa gttaaaaaga gtagagcaca aaggaattat ttgtacttta
     2521 ctcttttatt gttttgttaa aaaaactaat ttatattagt gattaaaata tatttaacta
     2581 gagtataagg atagtatata atcttataat tgatttatct gacaaattaa gataatatcc
     2641 taattaaatt gtagatattt atacataaca ctaaaagtaa tttgtttaac aaattaagat
     2701 aatatcctaa tcaaattgta ggtatttata cataacacta aaagtaattt gtctaacaaa
     2761 ttaaaatatt atccaattaa tataaaaatt acttcttttt aactgggaag catacctctg
     2821 ttacccaatt atcaggatta ctatcgttgc cagggcttac atgataaata ttaaacatag
     2881 gaccatccac atcatagtta ttatctgata tccaattacc aatagcctca caagcgtctg
     2941 caacttgatt gaaatttcca ttaacaattg cagttgcagc agtcacactt ggaacagtct
     3001 taaatttaac atgttcagta tctttatact ttccagatac agcaacttgt acttcaacat
     3061 ctacataatc ttctttatat ccagtatcat aaaaaactgc tttagaatac tttgggggtt
     3121 caatttgaac attctggtct tttgtctcta aaaatacttg atgccataac attccttcgt
     3181 cttggtaagt tggtataacc cttctaagtg tcatcatata ttttggtgca aaattcttta
     3241 tagttacatc ataatttttc ataatatcat ttcctccaat tcttttaata gtggtttcta
     3301 tttttaatag ttttttctgt gtatcttcta attgttcttt tacttgagaa tggtggatat
     3361 ttagatattt tatgagactt tctttatcgt tatattctgt caaaatttct tttatagaat
     3421 acaagccaaa gcccatatct tttagtgcat ggattctgtt tgtagtagaa agttggtctg
     3481 cactatagta tctatatcca ttagttttat tcgtatgaga aggagttaaa agtcctattt
     3541 catcataatg acgtaacata cgaatactaa ttttacttag ctttgaaaaa tcgcctatct
     3601 taaacatgtt tttgtctcct ttataaaggt acttttagct taatattaat ataaaccata
     3661 tcataatgtt agagtcaact aaaattataa ttaaattata ttgacatatg atgaaaaaaa
     3721 tattatactg aacatgttca gaaccgaaaa tgttaattgt tttggaggtc tattatgaaa
     3781 agtaatgata aagatgctag agaacgtata attgaagtta cattgaatct tttaaatgaa
     3841 gtagatgata ttgaggagat tacagttaga aaaattgctg agcgtgcaaa tgttggagtt
     3901 ggtttaataa attatcattt taaaacaaag gataatttgt tgagtactgc cataggagat
     3961 gtgatgtcaa atataatagc agagctatat gacgatagtg tatatactct aagacctatt
     4021 gaagatttaa aaaatttatt aaaaaaattg tgtgatactg gattacatta tgaaaaagtg
     4081 cttccttttg tattgaatca atgtataacc aatggagata tgcaagcaga acttgatatt
     4141 gtccctatgc ttcgtaaaat ttttggaaat aaaaaagatg aaatgagtct aagaatcatt
     4201 gccctgcaaa ttattttacc aatacagatt tctgctttat ctacagaatc atttcagtta
     4261 tacagtggta taaatataaa gaataaatat gagcgagata aattcattga tattttaata
     4321 gaaaatatta ttggagagga tgttgatgta agatgaaaat tataactatt ggttcaagtc
     4381 ttatcactgt tttacttttt ctttcaacta tggtttgtgg gttctggatt aagaataata
     4441 aggtaacaga tgcaagttct attaagttcc atatgaatag tgctattttt acagggatat
     4501 ttttattgat ttccacaatc cttttaatta tatatataaa aaaataataa tattattaat
     4561 aaataaagta tcagaaatta taaagacaag agtcttaaaa atttctgata ctttaccata
     4621 taattttatt aaacattaat tgtgtgtgaa aaaatatcac ttatttcaat ctaatactaa
     4681 atcttaagag tgagtataaa gtattagaaa ttaagaagca ttttttagtt caagtggatt
     4741 atctatacca aaataatcat ataaagtaga gcttatttcc tctaaatttc cattttggaa
     4801 aggtaattgt aaatttacct tttctaccac atctttaaat ccagcatcag tattttgatt
     4861 taaaaaatcc atatatacat caacagcttt tctgtaatct tcttgtgata attgccatat
     4921 ctgaagtgat acatcagatg caagaccata actcaagtaa taaaaaggaa cttggaagtt
     4981 atgagataca agtatccaaa aaggagcatt tttttctcta agtatattat tggaaactcc
     5041 atattcttcc tctaaatcaa aaaacaattt attgatatca tttagactca tatatggatt
     5101 cttgtatata atttcttgaa attcatcata aagacaagca tcaataatag tatttaaaac
     5161 aatcgataag tgttcttttt ttatagcttc agattgttta ccaaaaaaat catcaaaata
     5221 tttataaaat agaatttcta aagatgttga atgaacttca catacatcta tacttggttg
     5281 catcttatta tttaagttaa tactgttgta gtaattataa aaatgaccaa actcatgagc
     5341 aaaactagta acacctaaaa aagaattgtc ccatgtatta aacaagaaag gtgctttata
     5401 tttatttata taagtagtat atcctccagg tgatttgttt tttccagaag aataatcgta
     5461 caagtcatat tttttcatat agtcgaagct ctcttttagt tttggagata tatcttcaag
     5521 tactttatca aacttcctaa atgagcgatt tttatatact ttaatataaa tagaagaatc
     5581 agatggttta gatgaaatct ctctatataa tggaactatg taatctttta catcttgtct
     5641 aaatttttta gcttcttctt gagaatagtc tttgtttagg ttcatatagg cataatctat
     5701 ataattctta aatccttgct tacttgctat ttcagttctt gtctgtataa gttctaagaa
     5761 tatgttacca aatataggat tgtatttttt taagtaatct gaataaattt tcacatattc
     5821 ttcagggcta agatttggtc ttgacaaggc ttcttcaaag tctacctcta taccatctat
     5881 tgatactgta gatttagcta ataaatcttc atattttaca actaggtctt gctctttttt
     5941 aagcaaacct tcaacttctt tagaattaag ttttccaatg ttctttagat aattaaatgt
     6001 atcctttcca agttcttttt ctaattcttt agagaattta gaagttacaa atctatcttg
     6061 aaagtctttg tatgacatgt caacatctac tgatttactc ataagatact tatattcctt
     6121 agagtaaaat tcgtctgatg aatctatgtt atttctaatt tttgctatag taagtgtact
     6181 gtaaaaatcc tgataaattt tatcaacttc attaaataaa tttaattgtt ccttagctgt
     6241 tttagctgtt aaaagtttgt cgttacactt gttaatgttt tcgcaaattg actgtatatt
     6301 aggacgctta tattccattt tttcaaaagg aatagttcct ctaacagaat ctttttttgt
     6361 atcattagta taatttctta tgtatgatgc aaatataata aaaactgcaa ttaaaattag
     6421 aaaaacaaat attttcttct tggatttaac cataaaaatc ctccaatcat ggatatagtt
     6481 attaattatt ttactatatt aaatataaaa aatgcatgtt aagaaaattt aacataaaga
     6541 tatagataag attataaata atataaaaaa tttaacttca aaaaagtata tgaaatttat
     6601 actggtaaaa tgataaataa attttaagta caaaatagta aaagctatga tagttttaga
     6661 cctattatat gtaaaaaata tagatgtttt tggtgcaatt taaattaaaa gatatatata
     6721 aaaatttaaa atattccaaa cagaaattat aaaaattact atcattgtct ttatacaata
     6781 tttatactat aatagaataa taatttagag gaaagctcta aaaataaaca aattaagggt
     6841 cttaacagta gtgattttat gttaaggagg tataaagaaa gttgaaaaca atagttagaa
     6901 gacttattct ctacgcagat ggaatgcgtc ctactcaaat aatggtatct gggtttgctg
     6961 cgattattgt aatcggagca ttgttgttaa cactcccgat agcgtcgcag agtggagaga
     7021 gtataggctt attaaatgct ctatttacgg ctacttcagc ggtttgtgtt actggtctag
     7081 ttatggtaga tacagcaact tattggagtt tatttggaca gatagttata ataacattga
     7141 tacaaattgg tggtcttgga tttatgaccg tagccacaat gttttcactt atggcacgaa
     7201 aaaaaataca actaagagaa agattattaa tacaagagtc attaaatcaa gctgatttat
     7261 cgggacttgt aagacttaca agatttgtat taataataac cataacaata gagggaatag
     7321 gtgcactggt tttatcaact gtctttattc cacaatttgg tttgtctaaa gggatatggt
     7381 atagtgtatt tcacgcaata tcagcgtttt gtaatgccgg atttgacttg atgggcagtg
     7441 taagtggccc atttacatcg ttaaattctt atgtaaacaa ctttacagta tcaatgactg
     7501 tttgcgcact tatagtgctt ggagggctag gattccctgt tgtacttgat attgtaagaa
     7561 aaagaagatt ttcaaaatta aatgtgcatt ctaaggttgt attgttttca actgctacac
     7621 ttatttttgt gggtgcatta tttatttttc ttatagaatt taatcaaaaa gctactatgg
     7681 cggacttgcc tttaaaggga aaagtactat cagcaatatt tcaatcagta acagcaagaa
     7741 ctgctggttt taatacgctt gatttagcta ctttacgaga aagtagtgta tttgtaatga
     7801 taattttgat gtttattgga gcatcacctg catcaactgg tgggggtata aaaacaacaa
     7861 cactagctgt tttaatcatt acagttagaa gttttctatc aggaaaatca gatatagaag
     7921 cttttgaaag aagattagct ccatcaacta taaaaaaatc tcttggtata tttgtaatca
     7981 gtatatcagc agttattttt ggaacattga ttatttcaat aactcagcct aattttacat
     8041 tagttcaatc agcttttgag gttacatcag cacttgctac agttggttca agtttagctg
     8101 gaactccaaa cttaaatgct ttaggtaaga ttataataat aatctttatg tttatgggta
     8161 gagttggttc tcttacttta tttatggcta tactttctgg tggtagaaga aagagtcaac
     8221 caatcagata tgcagaaggt aaaattatgg ttggttaagt taccaaggag taatataaat
     8281 ttataatgga tttagagtag cactgtaaat ctgttgataa aataaatgag cctagatgta
     8341 attatatgaa gaaataaaat cgactaacga acaaaattaa ttaatgaaat aaaaaaacag
     8401 ggaaataaaa tacaaataaa aaggtaaatc aaaattaaat taatctgtgt atataaaatt
     8461 atatattgtg tataagtttt gtatgtgtaa acaattaatt taagagatat tatataaatt
     8521 gtgtattagg gaggaagttt cgagatgaag caatatatag tcattgggtg tgggagattt
     8581 ggaagttcag ttgcgtctac tatgcatctt ttaggacatc aagtaatggc aatagacaaa
     8641 aatgaagatt cagttcaaag tatatctgac aaggtaaccc attcacttat agtggatgtt
     8701 actgatgagc aagcgttaag gtcattaggt ttaggtaact ttgatgtagc agtagttgca
     8761 ataggttctg atataagggc atctataatg gcgactctta tagccaaaga aatgggtgta
     8821 gagttgataa tatgtaaggc aaaggatgaa ttacaagcta aagtgcttta taaaattggc
     8881 gcagatagag ttgtatttcc agaaagagat atgggagtaa gagttgcaca caatttagtt
     8941 tcagataata tattagacca tattgaactt gacccagagt attcaattgt tgaaatcgta
     9001 actccaaata gttgggttgg caagacactt atagagcttg aattaagagc tagatatgag
     9061 ataactgtac ttgctataaa aacaggtaaa aatataaatg ttacaccttc tccagatgag
     9121 gaacttacag ccggaagtat cctagttata atcggtcaaa atactagtat aacagcgata
     9181 acatctggaa ataaggggat aattagaaga agataattta ctatttaata tatatttaat
     9241 tgcaatgaaa gtagatagta tcatataatt atgaatagtt atatgatact atttttttaa
     9301 tcgaaggtag tatttatttg taagattaga taaagagaaa ttaaattaaa agtaaggagg
     9361 ctgtgctaat ataaaaattt ataagttatt agcatttaga taaaatgatt acaaatataa
     9421 acagtaagga taatgaaaag ttaaagtata caagagcact attaaaatca aagaatagga
     9481 ataaagagtc aaagttcata atagagggat acagaatagt aatgcttgca cttgaatgta
     9541 tggcaaacct tgattatgta tttatcaatg aagaatttga aaataagaaa gaacatgtaa
     9601 aactattaga agatttggat aaaaaaaaca caaagatata caagactact aataaaaact
     9661 ttaaagaatt agtggataca gaaaatactc aaggaataat aggtgtagtt tcatttaaga
     9721 aaaaaaaatt aagtgaaagt ataaataaaa aagataaatt tgtattgatt ttagacagaa
     9781 tacaagaccc aggaaatatg gggactataa taaggactgc tgattctgct ggagtagatg
     9841 ccataatagc actaaaggga tgtgtcgata tatacaaccc aaaagtaatt aggtctacta
     9901 tgggttctat ttttgatgtg aatataattg atgcttcaca agatgaaact gtggacatgc
     9961 ttaaatcatt ggattttaat atagtttcaa gttacttaaa tacagaaaat ttttatgaca
    10021 aaatagatta tggctcaaaa gtagcattgg tgataggaaa cgaagcaaat ggaataaatg
    10081 aagaacttgt atcaaagtct gatattttgg ttaagatacc tatatatggt aaagccgagt
    10141 cgttaaatgc tgcgataagc tctgctatac tgatgtatga aataaaaaaa tacttaattt
    10201 aatgtattgt aataaatata atgtcatgtt ataatcttga attaaatagt agagtatcaa
    10261 aaatagtcaa tatatattaa aaaaataatt aaattaatta tatattagat gtatattata
    10321 taaaaaataa ttgagtta
//
LOCUS       DAEPKC010000118        10068 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.119, whole genome shotgun sequence.
ACCESSION   DAEPKC010000118 DAEPKC010000000
VERSION     DAEPKC010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10068)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10068)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10068
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.119"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            95..460
                     /locus_tag="KR294_003264"
     CDS             95..460
                     /locus_tag="KR294_003264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0241319.1"
                     /translation="MKIRAEYTCLLEIVHDIIKGKWKTILIFELRQSNKTFSELQHNI
                     YGINQKMLIQQLKELRDFGIIDKISSAGYPLHVEYFLTNRGKKMLKAVEIMQEIGIEY
                     MLEHGQQEILDNKGICYNK"
     gene            538..1092
                     /locus_tag="KR294_003265"
     CDS             538..1092
                     /locus_tag="KR294_003265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBH0241320.1"
                     /translation="MSIALILIDIQNDYFKNGKCELFQSEETAENAKKILLFFRKNNL
                     PVIHIQHISTDKTASFFLPNTHGSEINKIVFPLDNEEIITKHTPDSFFETDLQSILEK
                     KNITNLVICGMMSHMCIDTSVRTAKKLRYDITLISDACTTKNLSWNNIEINANTVHQV
                     FMASLQNSFADVKNTDKFLSNYHK"
     gene            1312..1986
                     /locus_tag="KR294_003266"
     CDS             1312..1986
                     /locus_tag="KR294_003266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HBH0241321.1"
                     /translation="MNHHILIQFEYIARIITAGFCGALIGYERKNRLKEAGIRTHFIV
                     ALASALIIIVSKYGFNDIVGTPGIGLDPARVAAQVVSGIGFLGAGLIFIRNQSVSGLT
                     TAAGIWATAGTGLAIGSGLYLVGIVSSIIIVIVQITLHRDRKWMKLPTAEQVSLKISN
                     STDSIEYIEGKFKKSNIEIINMNIKRLDGDWLEVVIYTKLPKGYKKTNLLKLFSDNPL
                     IETLEI"
     regulatory      2341..2437
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            2491..2667
                     /locus_tag="KR294_003267"
     CDS             2491..2667
                     /locus_tag="KR294_003267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241322.1"
                     /translation="MFRDEMDKCTHMLTAYISSLYDYCDFIDTQLDDFILEYGENVVE
                     SCLHQVMVLVSKYN"
     gene            complement(2855..3094)
                     /locus_tag="KR294_003268"
     CDS             complement(2855..3094)
                     /locus_tag="KR294_003268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241323.1"
                     /translation="MKCSNCGSVNIEKGILTTGGIYAETIGLKYRGDGKLDKVINKTF
                     PVQSTIYSDLCLDCGEIVRTYIKDNTDRNWCKDKK"
     gene            complement(3228..4037)
                     /locus_tag="KR294_003269"
     CDS             complement(3228..4037)
                     /locus_tag="KR294_003269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH0241324.1"
                     /translation="MKDYYKIGEISKIYGIGRDSLMYYEEIGILRPVRDINGYRMYNI
                     SDIWKLNLIKEFRSLNFPMKKIKEYLDDRSIESTKNILNEELDLIDKKIAEFISHKEN
                     IIKRLSSIESVIQNTKIDEIEVVYIEKRKALELNADIKRDEDFDFLIQKLQKEYEDRF
                     NILGNNNIGSAFSTEAINKGIFNEFKSVFCFLESNEKVYNIVFDEGYYVTLNYTGSNS
                     NNKIYMEKVFKFIEENNYKIIADPIEIYKIDIHETGIVEEFVTEIQVPITK"
     gene            4821..7055
                     /locus_tag="KR294_003270"
     CDS             4821..7055
                     /locus_tag="KR294_003270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBH0241325.1"
                     /translation="MQNHNYIKMLNKKVEVLSKELDSRNFKLKTLNEIDFFSKIPNRE
                     FMYQHIDDCISKNIHIGIMLLNIDNFKLFNDIYGYLVGENLLITLTQNLLHFIPESKG
                     IVAYLKGEGFLIVLPNVSNKELNNMGATIIESARELKIKLPNEKEIYSNVTFSIGSTI
                     WNGEPNMTTLMLFNQVYSALKKAKSEGKNRYILFDFKDNSFYNKLENDKEFLSEISHV
                     LQTKQIEVFYQPLYNIKNNTIVGCEALARWRHPIKGLLTPDKFIPLFEQFGLITELDL
                     HLFEENCKNIRRWIDNNDVFVPICCNFSRLHFFNPNFPSMLKGITEKYSVSTSNFSIE
                     ITENILIENTNTIIQQLAELRSYGFSVSMDDFGSGYSSFGMLQNLPFDIIKIDRIFLS
                     HNLNDFKNTTILYSIINIARALGMLTVCEGVETEQHVEFIKSINCDIAQGYYYAKPME
                     CKEFEKLLSKENNSEKMFIKYSDIGKSLIEKIFDGFFIMQDMKKLRANVTEDIQWFDF
                     YNKTEITSFPKVIEHFEKHIKGKKFSILYKSITPHNTESDSLLISGEAVLSDEASEHQ
                     KYSNFYFSANCIISENKLLLAKLHLDLIKTAGYINEFESYSIPKMTNTHLDESNILSQ
                     FYSMLPVGIIRYDLFGDMIITYMNEEMFDIIGYTKEQFFGEMGGNLRAIVHPDDLDFV
                     YKKSLDMIDTNKIEPFLYRFIKRDGQIVTVMYTQCNLSAIDGRSIAQGMYVDVNKIKN
                     LTKI"
     gene            7086..7919
                     /locus_tag="KR294_003271"
     CDS             7086..7919
                     /locus_tag="KR294_003271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBH0241326.1"
                     /translation="MFKEIFLRTFPGFLIIRDSNYRIIFINDNLKNLIKSYMQDNPLG
                     MTNIEIAKKLPDNIAKFFTDSHNIQLDWEKNYPYDKISNWILEFKKDTTSYWNVLEYK
                     VDVDEKTYIITMANDITKLYEENKRNLHYSITDPLTGAYNRKYLNDRFDIFIGDYIVL
                     IDLDNFKMINDYEGHNVGDKILCDFVSLLNKELINSTSIIRLGGDEFIVIFSSDVDKN
                     YVYSQLEALRENFLKVFSKYKYLSFSYGVDTVKRNLKLTIVELDKKMYKNKKKFDKND
                     Y"
     gene            8159..9892
                     /locus_tag="KR294_003272"
     CDS             8159..9892
                     /locus_tag="KR294_003272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HBH0241327.1"
                     /translation="MSILLKKAPKLAKHIITSFYINRDIDEVLKYLCENVTWIGPGEQ
                     EFLTSFNEIKNYFYAGQDEIPSCDINNDIFETVSEDENRCMVLGRYTVRTKENTQMIL
                     EVNQRCTFEIIEDRGKLLVKHMHISNPYGEMQLDEYFPTKIGTQSYDYLQRLLKEKTE
                     VIEMITNNINGGLKGSNDDNTYSFFYVNEGLPKILGYTYDEFMEMSGGSAVGAVYPPD
                     LPKALEDCERCFAKGPTYSSEYRIRKKDGTLMWVLDSGMKSLNSDGIVKINSIITDIT
                     QLKNIESELKLERERYRIALQNITDIMFEYDIENDTLIKYQRVEIDKKIELENFETKN
                     YSKLLESGKIIHLDDIGKLLEVLHGNLRETIEIRQVNSLTKNEWRWIRVQCSVIYDSD
                     HNPIKTIGVLKDITEDKSKLESLINQAQRDPLTQLYNQRVSQNLIEEYLCSSDSKNND
                     ALLVIDIDDFKTVNDTFGHLEGNEVLVAVSKILLHNTHDKDIVARIGGDEFTIFIKSL
                     TKDLIIKITNDILNDASKIKVKDNHKITLSIGIAFTDDSTKLYKDLFSKADKALYLSK
                     ADGKNCYSTYE"
BASE COUNT         3938 a         1233 c         1307 g         3590 t
ORIGIN      
        1 ataaaacata aaatttatat acagttcata tatatttgtc atatcacaag acaagtgata
       61 taatttatta tcattttact gggggtgata tgctatgaaa ataagagctg aatatacatg
      121 tcttcttgaa attgtacatg acataatcaa aggaaaatgg aaaactatcc ttatatttga
      181 attaagacaa tctaataaaa cattttctga attgcaacat aatatttatg gaataaatca
      241 aaaaatgttg attcaacaat taaaagagtt acgtgatttt gggattattg ataaaataag
      301 ttctgctgga tatccattac atgttgaata ttttcttact aatcgtggta aaaaaatgtt
      361 aaaagcagtg gaaataatgc aagaaatagg aatcgaatat atgcttgaac atggtcaaca
      421 agaaattcta gataataaag gaatttgcta caataagtaa tcctatacat accaaaaagt
      481 aagtaattta cattttttac aatagtatta taataaaaat aaataggagg tataatcatg
      541 tctatagctt taatattgat tgatattcaa aatgattatt ttaaaaatgg aaaatgtgaa
      601 ttatttcaat cagaagaaac tgctgaaaat gctaaaaaaa tactactgtt ttttagaaaa
      661 aacaatttac cagttattca tatacagcat atatcaacag ataaaacagc ttcttttttt
      721 cttcctaata ctcatggttc agaaataaat aaaattgttt ttccactaga taatgaagaa
      781 attataacta aacacacacc agatagtttc tttgaaacag atttgcaaag tatccttgag
      841 aaaaaaaata ttactaatct agtaatctgt ggaatgatga gccatatgtg tattgataca
      901 agtgtaagaa cagcaaagaa acttcgatac gacataactc taataagcga tgcatgtaca
      961 acgaagaatt tatcttggaa taatatagaa attaatgcaa atactgtaca tcaagtattc
     1021 atggcatcac tacagaacag ttttgcagat gtaaaaaaca cagataaatt tttatctaac
     1081 tatcacaaat aaaaacatac actatgttaa aagagcaagt ttgatttatt taagcttgct
     1141 ctttaatcat ttaaaattag atgctttcta tcatttttat atacataata tacgtttata
     1201 cattttatat tcatatataa ctattatata aattttaaac tttactatat tcacataaaa
     1261 aatgtagtat tatagtatat ataatattat atagaagggg gtgctagata aatgaaccat
     1321 catatattga ttcaatttga atatatagca agaatcatta ctgctggttt ctgtggggct
     1381 ttaattggat atgagagaaa gaatagacta aaagaagctg gaatacgcac tcattttata
     1441 gtggcattag cttcagcact tataatcatt gtttccaagt atggatttaa tgatatagtg
     1501 ggtactccag gtattggtct agacccagcc cgcgttgcag cacaagttgt cagtggtata
     1561 ggttttttag gtgctggatt aatatttatt agaaatcaat cagtaagtgg tcttactaca
     1621 gctgctggta tatgggcaac agctggtaca ggtcttgcca ttggctctgg attatactta
     1681 gttggtattg tttcaagtat cattattgtt attgtacaga taacacttca tagagatagg
     1741 aaatggatga aactccctac agcagagcaa gtttctctta aaatttctaa cagcactgat
     1801 tccatagaat atattgaagg taaatttaaa aaatctaata ttgaaattat aaacatgaat
     1861 attaaacgcc ttgatgggga ttggttagaa gtagttatat atactaagtt acctaaagga
     1921 tataaaaaaa caaatttatt aaaattattt agcgataatc ctcttataga aactttagaa
     1981 atataatata aaaattgaag cttaaaaata ataatatatt taatcaaggt caatatataa
     2041 ataattacgg gatgagtcta tataaaattc atcccttgtt ttttgccatt catatatatt
     2101 ttttcaagat atttttgttc atctattatc tagccaagta actcttgtga actaaacttt
     2161 ttaatacaaa aacttcaata caaaactaaa tataattttt attaaatatt ctacatgtat
     2221 agtttatttc ttgagtgaaa aatagatttc atattgttaa gatactgtta aatatttcaa
     2281 ttttctgaca agtatgttga acaataactt atcctagtgt attattttag ttgtagaata
     2341 aaactaaatc ggcaaaacta gagaaattta gtgacgcaaa gctataggga ctaacgctta
     2401 taaaataaac tatgagttat gtcagccagt tgccaaaaag atattgttct ttttgtttta
     2461 tgaaagtttt ttagggggat agtaatatat atgtttagag atgaaatgga taaatgtaca
     2521 cacatgttaa ctgcttatat cagtagttta tatgattatt gtgattttat agatacacag
     2581 ctagatgatt ttatactaga gtacggagaa aatgtagtag aatcttgttt acatcaagtg
     2641 atggtattgg taagtaagta taattaaata gaaattgttt tctagagaac cctttttagt
     2701 tttatctaca tttaaaaatg ttattatatt aaaaaactaa tctcccctat atgcaaagtt
     2761 ttcttccata taacaatttc ttcccattta tactttttca cttgtatctt taataaaatt
     2821 caacttcaaa tattaatata cttcaaaaat tattctattt cttatcttta caccaattcc
     2881 tatcagtatt atcctttata taggttctaa ctatttctcc acaatctaaa cataaatctg
     2941 aatatatagt agattgtact ggaaaagttt tatttataac tttatctaat tttccatctc
     3001 ctctatattt taatccaata gtttcagcat atatgccacc agttgttaaa attccctttt
     3061 caatatttac acttccacaa ttagaacatt tcacatttat aaccccctaa acaattattt
     3121 tttcatgcta tcttataatt taaaatataa tttgctaccg attttataac acagtggcaa
     3181 atcaacattt tttcattcta tttaccatct aatccattga aatatagcta tttagttata
     3241 ggaacttgaa tttccgttac aaactcctct acaattccag tctcatgtat atctatctta
     3301 tagatttcta tagggtcagc aattatctta taattatttt cttctataaa tttaaacacc
     3361 ttctccatat atatcttatt attagaatta ctcccagtat aatttaaagt tacataatat
     3421 ccttcatcaa aaactatatt atatactttc tcattacttt ccagaaaaca aaatacagat
     3481 ttaaactcat taaatatacc tttattaatt gcttcagtag aaaaggcaga accaatattg
     3541 ttgtttccaa gtatattaaa tctatcttca tattctttct gaagtttttg aattaaaaaa
     3601 tcgaagtctt catccctctt tatatcagca tttaattcta aagcttttct tttttctata
     3661 tatacaacct ctatctcatc tatttttgta ttttgaatta cactttcaat tgaactcaat
     3721 ctttttataa tattttcctt atggcttata aattcagcta tttttttatc aattaaatcg
     3781 agttcttcat ttaaaatatt tttcgtagac tctatacttc tgtcatctag gtattctttt
     3841 attttcttca ttggaaagtt caagcttcta aattctttta ttaaatttaa tttccatata
     3901 tctgatatat tatacattct atatccattt atatctctaa ctggtcttag aatgcctatt
     3961 tcttcataat acattaatga atctctacct attccatata ttttagatat ctctcctatt
     4021 ttatagtaat ctttcattta tataataaac tcctccgaaa tcttattttt attttaaatc
     4081 aacattatta ctctataata ctatagtatt agaatatact aaaaaaatct ttaaaacaag
     4141 gataggaaaa taaacatcct aataattaat tattaaaata tttttatatt gtaatattag
     4201 gtatagtatt tataacttca acttttttat aaatatattt tagttttata tagttttatg
     4261 tttacagcta ttatatccat ctctatgtaa tatttttcat attaaaactg atttctatag
     4321 attaatattt tataaattta gtaaatgaat atttattata gtctttaaca aaaaatacaa
     4381 gaataaactt aattttaata actaaaatta attatgcaaa attattaata tggtattaaa
     4441 ttatgtataa aaagttaatt atgaataaaa taattatgcc tttgaaaaat cattaaactt
     4501 aaaattaatt ataaaaaaac tctaccttac taactataca gctcacaatc tatctattta
     4561 tgaaaaaata tgatataatt gcattcaaaa aggaaatctt tcaatatact agaatttaag
     4621 cattaactaa ttttatctaa tattattact aaactaaaaa atatttgtat ttgtagcatt
     4681 ggagcaagta acttaatgta tattcatttt aaatacttat ttaaaattta gcatttaaat
     4741 tatttacaaa ttaacattta aatacttcta gcataaatac agttgtcatt aaaatttaaa
     4801 gtatcttatg gaggaatacc atgcaaaatc ataattatat aaaaatgtta aataaaaagg
     4861 tagaagtatt atctaaggaa ttagatagta gaaattttaa attaaaaacc ttaaatgaaa
     4921 tagatttttt ttctaaaata ccaaacagag aatttatgta ccaacatatt gatgactgta
     4981 tttcgaaaaa tatacatata ggaatcatgt tattaaatat cgataacttt aaattattta
     5041 atgatatata tggataccta gtcggagaaa atttattaat tactctaact caaaacctat
     5101 tgcactttat tccagaatca aagggaatag tcgcttattt aaaaggagaa ggttttttaa
     5161 ttgtacttcc aaatgtatca aataaagagt taaataatat gggtgcaact attatagaga
     5221 gcgcccgaga attaaaaata aaacttccta atgaaaaaga aatatactcc aatgttacat
     5281 ttagtatcgg cagcactatc tggaatggtg aaccaaacat gactactttg atgcttttca
     5341 accaagtata tagtgcttta aaaaaggcta aaagtgaagg taaaaataga tacattctat
     5401 ttgattttaa agataatagt ttttacaata aattagaaaa tgataaggag ttcttatcag
     5461 aaatatcaca tgttctacaa actaaacaaa ttgaagtatt ttaccaacca ctttataata
     5521 taaaaaataa tactatagtt ggatgtgagg cacttgcaag atggagacac cctattaaag
     5581 gacttcttac tccagataaa tttattcctt tatttgaaca gtttggtctg ataacggaat
     5641 tagatttgca tttatttgaa gagaactgta aaaatataag aagatggatt gataacaatg
     5701 atgtttttgt tccaatttgt tgtaactttt ctcgtcttca tttttttaac cctaattttc
     5761 caagtatgct aaaaggtatt actgaaaagt acagcgtctc tacatcaaat tttagcattg
     5821 aaataacaga aaatatatta atagaaaata caaatacaat tattcaacaa ctagctgaac
     5881 ttcgttctta tggtttttct gtatcaatgg acgattttgg ttctggatat tcatcttttg
     5941 gtatgttgca aaatctacct tttgatataa tcaaaattga taggatattt ttatctcata
     6001 atttaaatga ttttaaaaat acaaccattt tgtactctat aataaacatt gcaagagctc
     6061 ttgggatgct tacagtatgt gaaggtgttg aaacagaaca acatgtagaa tttattaaaa
     6121 gtataaattg tgatatcgcc caaggttatt attatgcaaa acccatggag tgcaaagaat
     6181 ttgaaaaatt actatctaaa gagaataatt cagagaaaat gtttataaaa tattctgata
     6241 taggaaaatc tttaatagag aagatatttg atggattttt tattatgcaa gatatgaaaa
     6301 aactaagagc taatgtcact gaagacattc aatggtttga tttttacaac aaaactgaaa
     6361 ttacatcttt tcctaaagta atagagcatt ttgaaaaaca tattaaaggt aaaaaatttt
     6421 ctattcttta caaaagtata accccacata atactgaatc agattcatta ttaattagtg
     6481 gagaagccgt tttatcagat gaagcttctg aacatcaaaa atatagcaat ttctacttta
     6541 gtgcaaattg tataatttca gaaaataaat tactcttagc aaaattacat ttggatttaa
     6601 ttaaaactgc tggctatata aatgaatttg aatcatattc aatacctaaa atgacaaata
     6661 cacatcttga tgaaagtaat attttatcac aattttattc aatgttgcct gtaggtataa
     6721 ttcgctacga tttatttggt gatatgatta ttacttatat gaatgaagaa atgtttgata
     6781 ttataggtta tacaaaagaa cagttttttg gtgagatggg cggaaattta agagcaattg
     6841 ttcatccaga tgatttagac tttgtttata aaaaaagttt ggatatgatt gacacaaata
     6901 aaattgaacc atttttatat agattcataa aacgagatgg tcaaattgtc acagttatgt
     6961 atacacaatg taacctttct gcaattgatg gaaggtcgat tgcccagggt atgtatgtag
     7021 atgtaaataa aataaaaaat ttaacaaaaa tctagtacaa agtattttat tttggagaaa
     7081 ttaatatgtt taaagaaatt tttttaagaa cttttccagg atttctaatt ataagagatt
     7141 ctaactacag aattatattt ataaatgata atttaaaaaa tttaattaaa agttatatgc
     7201 aagataatcc acttggaatg actaatatag aaatagctaa gaaactccct gataatattg
     7261 ctaaattttt tacggattct cacaatattc aattagattg ggaaaaaaat tatccttatg
     7321 ataaaatttc aaattggatt ttagagttta aaaaagatac tacaagctat tggaatgttt
     7381 tagaatataa agtagatgtt gatgaaaaaa cctacataat tactatggcc aatgatataa
     7441 caaaactcta tgaagaaaat aagagaaatc ttcactactc aattactgac ccattaactg
     7501 gagcatataa tagaaaatat ttaaatgata gatttgacat atttatagga gattatattg
     7561 tactaattga cttagataat ttcaaaatga taaatgacta tgaaggtcat aatgtaggag
     7621 acaagatttt atgtgatttt gtttcacttt taaataaaga attaataaat tctacttcta
     7681 ttataagatt aggaggagat gaatttattg ttatattctc tagtgatgtt gacaaaaatt
     7741 atgtttattc acaactagaa gccttaagag aaaatttttt aaaagtattc tctaagtata
     7801 agtatctttc atttagttat ggtgttgata cagtaaaaag aaatttaaaa ttgacaatag
     7861 ttgaattgga taaaaaaatg tataaaaaca agaaaaaatt tgataaaaat gattattaat
     7921 attgttattt taaaataaat taaaattatc tttctttttt taaacttgta cattagttta
     7981 taaatatgta tctatacaag atattgacat taagtactga agcatatatt gtttcagttc
     8041 ttttttgtta aaattaactt atttaacaaa gatatcatag tttaacaaag cttttaattt
     8101 aaatatattg atgtataata taattaaaat ataatagcaa aaagaaagga ggaatatcat
     8161 gagcatactc ctaaaaaaag cacccaaatt agcaaaacat attataacaa gtttttatat
     8221 aaatcgggat attgatgaag tattaaaata cctttgtgaa aatgttacat ggatcggacc
     8281 aggagaacag gaatttctca cttcttttaa tgaaataaaa aattattttt atgcaggtca
     8341 agatgaaatt ccttcttgtg atataaataa tgatatattt gaaactgtaa gtgaagatga
     8401 gaatagatgt atggtattag gaagatatac tgttcgaact aaagaaaata ctcaaatgat
     8461 tttagaggta aatcaacgtt gtacatttga gataattgag gatagaggaa aattattagt
     8521 aaagcacatg cacatatcaa acccttatgg tgaaatgcaa cttgatgaat actttcccac
     8581 taaaattgga actcaaagtt atgattattt gcaaagatta ctaaaggaaa aaacagaagt
     8641 tattgaaatg attacaaata atatcaatgg tggcttaaaa ggtagcaatg atgataatac
     8701 atactcattt ttctatgtca atgaaggatt gcccaaaata ttaggataca catatgatga
     8761 gttcatggaa atgagtggtg gttcagcagt gggtgctgta tatccaccag acttacctaa
     8821 agcactagaa gattgtgaac gatgttttgc aaaaggacct acatattcat ctgaatatag
     8881 aatccgaaaa aaagatggaa cattaatgtg ggtattagat tctggaatga aatcattaaa
     8941 tagtgatggc atagtaaaaa ttaatagtat tattactgac ataacccaac taaaaaacat
     9001 agaatctgaa ctaaaattag aaagagagcg atatcgtatt gctttgcaaa atattacaga
     9061 tatcatgttt gagtatgata ttgaaaacga tacccttata aaatatcaac gtgtagaaat
     9121 tgacaaaaaa attgaattag aaaattttga aacaaaaaat tactccaaac tattagaatc
     9181 tggtaaaatt attcaccttg atgatattgg aaaactacta gaagtacttc atggaaatct
     9241 tcgtgaaaca attgagataa gacaagtaaa ttcattaact aaaaatgaat ggagatggat
     9301 tcgtgttcaa tgttcagtta tatatgatag tgaccataac cctatcaaaa caataggcgt
     9361 tttaaaagac ataactgaag ataaatctaa attagaaagc ttaattaatc aggctcaacg
     9421 tgacccacta acacaattat ataatcaaag agtatcacaa aatcttattg aagagtatct
     9481 atgtagttct gattccaaaa ataatgatgc tctattagtt attgatattg atgattttaa
     9541 aactgtaaat gatacttttg ggcatttaga gggaaatgaa gttttagttg ctgtatcaaa
     9601 aatactatta cataacacac atgataaaga catagttgct cgaattggtg gagatgaatt
     9661 tacaatattt ataaaatcat taacaaagga tttaataata aaaattacta atgatatttt
     9721 aaatgatgca agtaaaataa aagtaaagga caatcataaa ataacattaa gtattggtat
     9781 tgccttcact gatgattcaa ctaaattata taaagattta ttttctaaag ctgataaagc
     9841 tctttatcta tcaaaagcag atggcaaaaa ttgttatagt acatacgaat aataaagcta
     9901 tttatacgac caagaatgaa cctttaaatt taatttcata gtctaacaat caaagagttg
     9961 aagctaatct tatagctagt caactagttc ctagaaaaaa tttaaacaat atatttattg
    10021 atactgctca tttttctaaa gagcaaattt atataaaaaa ttaaactt
//
LOCUS       DAEPKC010000119         9854 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.120, whole genome shotgun sequence.
ACCESSION   DAEPKC010000119 DAEPKC010000000
VERSION     DAEPKC010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9854)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9854)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9854
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.120"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            456..1364
                     /gene="trxB"
                     /locus_tag="KR294_003273"
     CDS             456..1364
                     /gene="trxB"
                     /locus_tag="KR294_003273"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HBH0241328.1"
                     /translation="MVDIIVIGAGPAGLTSAIYAMRAGLSVTVFEKNIYGGQVASTSE
                     VENYPAVQKISGVEFSNNIYNQAVAQGVDIQFDEVEEINLEGKVKVVKTSSGEHKAKA
                     VILANGVERRKLGCAGEQEFTGRGVSYCATCDGAFFKDKEVAIVGGGNTALEDALFLA
                     NNCTKVYLIHRRDSFRGEEVLEKSVKARENIEILYSHGVEKIEGEKTVSKIEVKNLKT
                     EEKRTIDVSGIFIAIGLKPNNKMFENVLDLDEGGYIISDESCTTSVEGVYVAGDSRTK
                     FLRQIITAASDGAIAAVQAANYINVE"
     gene            complement(1454..3277)
                     /gene="typA"
                     /locus_tag="KR294_003274"
     CDS             complement(1454..3277)
                     /gene="typA"
                     /locus_tag="KR294_003274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HBH0241329.1"
                     /translation="MSQKHKIINIAVIAHVDAGKSTLVDAFLSQSGVFRKNEVVKDCV
                     MDSNDLEKERGITIYSKNCAINYEDYKINIVDTPGHSDFSSEVERVMKTVDTVILLVD
                     ASEGPMPQTRFVLQKSLEFGLKPILFINKIDKKDQRAEEVVNEVFDLFVDLNATDEQC
                     EFPIIYGIAKQGIAKLEMDDDSEDLSPLFKTIVNHVEAYPNYDNEPLQFQISALAYDD
                     YVGRLGIGRIYKGTLKNNTQVAICREDSVVSKGKVSKLSVYEGLKQVEVDEATSGEIV
                     VIAGIPDISIGETICDLDSPLPMEMIKIEEPTLSMNFLVNDSPFVGKSGKFVTTRHLK
                     DRLEKELEVNVGLKVEPLDTTDGYKVSGRGELHLSILLENMRREGYEVGVSKPEVLMH
                     KEDGKLMEPIERVVVNCPEVYSGTIINELNMRKGMMESMSIEGDYVKIEFLAPTRGLL
                     GYRSEFINATRGEGTLVRSFEKFEEFKGEIPSRGNGVLIAQGPGVTMGYSLNALSDRA
                     VMFVDPGVEVYEGMIIGMNSRKDDMVVNPCKNKKMSNVRASGSDDAIKLSPPRIFTLE
                     EALEFIEDDELVEITPDSIRLRKRFLNEHDRLRYNKSRQGK"
     gene            3489..3731
                     /locus_tag="KR294_003275"
     CDS             3489..3731
                     /locus_tag="KR294_003275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241330.1"
                     /translation="MLEVTKIIIKYFASESDTFVKEEVCNFEELLKWSHKFIEGKKIE
                     DVLYIKSKENYKVNVIKSLEIKELEIVRKQQIPPYM"
     gene            3879..4070
                     /locus_tag="KR294_003276"
     CDS             3879..4070
                     /locus_tag="KR294_003276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1450 domain-containing protein"
                     /protein_id="HBH0241331.1"
                     /translation="MIRVCPNCSNVDVNKLKTLVGEENVKTGCIGQCRAFKKEAVGII
                     DNELEIKETEAEFFEACKE"
     gene            4361..6862
                     /locus_tag="KR294_003277"
     CDS             4361..6862
                     /locus_tag="KR294_003277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HBH0241332.1"
                     /translation="MSSNKVVESYKITGMTCAACAKAVERVTKKMDGVYDQNVNIATE
                     KLKIEYDNSKVNFDDIKQVVEKAGYGIIKEESNKKIDMKIDGMTCAACAKAVERVVKK
                     LDGVESISVNIATDKANIDYDPSKVKLSQIKAAIEKAGYKPIEEVRNKVDVDEDKLRK
                     EREMKSLFVKFIVAIVFAVPLFYIAMGPMIIKPIGPWPLPEIINPMTNTFNYALIQLI
                     LVIPVMIAGYKFYINGFKSLFSLSPNMDSLVAIGTLAAFLYSLYTTLQIANGQIQGMH
                     HHQLYYESAGIIIALILLGKYLESKSKGKTSEAIKKLMGLQPKTAIVLVDGKEVETPI
                     EEVEIGDILLVKPGTKIPVDGVVIEGYTSVDESMLTGESIPVEKNVGSKVTGASINKN
                     GVIKFKAEKIGGDTALAQIIKLVEDAQGTKAPIAKLADTVSGYFVPIVIAIAVVASLL
                     WFLIGGKDIVFVLTIFISVLVIACPCALGLATPTAIMVGTGKGAENGILIKGGEALES
                     AHKVNTVIFDKTGTITEGKPKVTDIVLNNNVKEEYLIKIASSAEKGSEHPLGEAIVKY
                     GEEKNIKFEKVDNFKAIPGAGIQVTINDESILLGNRKLMNDNNIKLGDLEEKSNILAS
                     QGKTPMYIAVDGNLSGIIAVADVVKESSKKAIEILHDMGIKVAMVTGDNAKTANAIAN
                     QVGIDMVLAEVLPEDKSKEVEKLQNQGKFVAMVGDGINDAPALAKADIGIAIGSGTDV
                     AIESADIVLMKSDLIDVPTAIKLSHETIKNIKQNLFWAFGYNTIGIPVAAGILYVFGG
                     PLLNPMIAAAAMSLSSVSVVSNALRLKNFKAYKRD"
     gene            7022..7690
                     /locus_tag="KR294_003278"
     CDS             7022..7690
                     /locus_tag="KR294_003278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0241333.1"
                     /translation="MNSSILVIEDDSNIQELISEFLSAEGYQVDTANDGLEGIQKFKQ
                     GSYDLVILDIMMPNLDGYGVCKMIRKSSSVPIIFLTALNDEGDQLKGFDLECDDYITK
                     PFSFNLLIKRVEAILRRSNKTINDKFIVFEKLKLDLNTYIAEIDGEPIELTLKEFNIL
                     KALIEKYPQVITREGLLDSIWGYDYYGDTRIVDAHIKNIRKKISLPYIKTVKGIGYTL
                     EKDI"
     gene            7674..8951
                     /locus_tag="KR294_003279"
     CDS             7674..8951
                     /locus_tag="KR294_003279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HBH0241334.1"
                     /translation="MRRIFDKWEKLSIKYKLFSITTSLLIALALIIYLILYFLLPSYY
                     HEYKIESLQESLKSLVDSSIHFDTYTLEERLYYMAKDQNLAILLKDNQGKIVYGKNEV
                     VILRYSKYMINSLEDEYRTSIPIYTKDAKDGPYTLELVMPLQPIDEANEVIRKLMPYI
                     ISIAILIAIIGAYIYSIVITKPLINIIESEREQEYRRKDFVATISHELKTPITIISGQ
                     IEGMIYSVGKYKDRDTYLKKSYECTQELKDLVNEMIEVSKSEILEKDLKLVSINISEL
                     LNRLVKRQVFLIEEKHMKTILKIEENLEIKADQERITKAINNIINNAIKYSPEESELI
                     IRLYDKNKRISKKTSNQRVVLEIENTGVTIEKRYLEEIFNPFYRIEKSRSRKTGGSGL
                     GLYIVSQIFKSHGFDYSIKNKENSVVFTVEFKN"
     gene            9352..9573
                     /locus_tag="KR294_003280"
     CDS             9352..9573
                     /locus_tag="KR294_003280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241335.1"
                     /translation="MDRLKRDMKNMKEDLKEGVKKTAYVMKNTAEDLKDDAQGAMVNL
                     EMKKDEMMERYEQKKFSKELEKQMKNEMK"
BASE COUNT         3934 a         1110 c         1660 g         3150 t
ORIGIN      
        1 atcataattg gttcaacaaa agtatatagt taataatgtt taatttgaag aaattgttag
       61 tgtgaaatta catatatatt caaattaaat tcataaatat ttcacataat aatagtatac
      121 tgtaaacaaa aggaggtatt aaatatggga atagtactta taacagcagc attagttttg
      181 gttatgtatg gactttcaat tctatcatat atatcagaaa gcaatatatt agaagacact
      241 gtaaatgata accaataagg ttttgaatta tataaataag tgagaactgt aaataaaagt
      301 taatttttat ttgcagtttt tttatatata tgtaaaataa agttaattaa taaaaaataa
      361 tgttttgttt atagtatata tggataataa tagtaaagta taagaatgat gagaataata
      421 tataagaaat aataatataa agagaggtaa acgttatggt agatatcatt gtaattggtg
      481 ctggaccagc aggtttaact tcagcaattt atgctatgag agcagggtta agcgttacag
      541 tatttgaaaa aaatatttat ggaggtcaag ttgcaagtac ctctgaggta gaaaattatc
      601 cagcagttca aaagatttct ggggtagaat tttctaataa tatatacaat caagcagttg
      661 ctcaaggtgt tgatattcag tttgatgagg ttgaagagat aaatttagag ggaaaagtaa
      721 aggttgtaaa aacttcttca ggtgaacata aagcaaaggc tgttattctt gcaaatggag
      781 ttgaaagacg taaattaggt tgtgcagggg aacaagaatt tacaggtaga ggagtatctt
      841 actgtgcaac atgtgatgga gcctttttta aagataaaga agttgctata gtaggtggag
      901 gaaatactgc actagaagat gctttatttt tagctaataa ttgtacaaaa gtgtatttaa
      961 ttcacagaag agatagtttt agaggtgaag aagtgttgga gaaatctgtg aaagcaagag
     1021 agaatattga gatactttac agtcatggtg tagaaaaaat agaaggagaa aagactgtat
     1081 cgaaaataga agtaaaaaac ttaaagactg aagaaaaaag aactatagat gttagtggta
     1141 tttttattgc tataggtctt aaacctaata ataaaatgtt tgaaaatgtt cttgatttgg
     1201 atgaaggtgg atatataatt tcagatgagt cttgtacaac atcagtagaa ggtgtatatg
     1261 tagcaggaga tagtagaact aagtttttac gtcaaataat aacagcagca tcagatggag
     1321 ctattgcagc cgttcaagca gctaattata taaatgttga ataatataaa tttcaaataa
     1381 aaatagccat ataaactgaa ataatttttc agtactatat ggctattttg ttaattagag
     1441 gtaaatgtac gttttattta ccttgtctag atttgttata tcttaatcta tcatgttcat
     1501 ttaagaatct ttttctaagt cttatagaat caggtgtaat ttcaactaat tcatcatctt
     1561 ctataaactc tagagcttct tcaagagtaa atattctagg aggagataat tttatagcat
     1621 catctgaacc agaagcacgt acgttactca ttttcttgtt tttacaagga ttgactacca
     1681 tatcatcttt tctggaattc ataccaatta tcataccttc gtaaacttct acaccagggt
     1741 ctacaaacat tacagctcta tcacttaagg cattaagaga ataccccata gtaacaccag
     1801 gtccttgtgc tattaaaaca ccatttcctc ttgaaggtat ttctccttta aattcttcaa
     1861 atttttcaaa tgaacgaact aaagtacctt ctccacgagt agcgtttata aattcacttc
     1921 gatatcctaa aagaccacga gtaggtgcta agaactctat ttttacatag tctccttcta
     1981 ttgacataga ctccatcata ccttttctca tgtttaattc atttataata gtaccagagt
     2041 aaacttcagg acagtttaca acaactcttt ctattggttc cattagtttt ccatcttctt
     2101 tatgcattaa aacttcaggt ttagaaacac caacttcata accttcacgt ctcatatttt
     2161 caagtagtat agataagtga agctctccac gtccagaaac tttgtatcca tcagtagtat
     2221 caagaggttc aactttaaga ccaacattta cttcaagttc tttttcaagt ctatctttca
     2281 aatgtctagt tgtaacgaat tttccacttt ttccaacgaa tggagagtcg tttactaaga
     2341 agttcataga aagagtaggc tcttctattt ttatcatttc cataggtagt ggactatcta
     2401 aatcgcatat agtttcacct atagatatat caggaatacc agctataaca actatttctc
     2461 cactagtagc ttcatcaact tcaacttgtt ttaaaccttc atacacagaa agttttgata
     2521 cttttccttt agatacaaca gaatcttctc tacatatagc aacttgtgta ttgtttttaa
     2581 gagtaccttt gtaaattcta cctataccaa gtctacctac ataatcatca tatgcaagag
     2641 ctgatatttg gaactgtaga ggttcattat cgtaattagg ataagcttca acgtgattta
     2701 caatagtttt aaatagagga gaaaggtctt cactatcatc atccatttca agtttagcaa
     2761 taccttgttt agcaatacca tatattatag gaaattcgca ttgctcatct gttgcattta
     2821 agtctacaaa taaatcgaaa acttcattaa ctacttcttc cgctctctgg tcttttttat
     2881 caatcttgtt tataaataat attggtttta aaccgaactc taaagatttt tgtaaaacga
     2941 atctagtttg aggcattggg ccttcactag catcaactaa tagaataact gtgtcaacag
     3001 ttttcataac acgttcaact tcagaagaaa agtcactgtg tcctggagta tcaactatgt
     3061 ttattttgta atcttcatag tttattgcac agttttttga atatatagtt atgcctcttt
     3121 ctttttcaag gtcgttactg tccataacgc agtctttaac tacttcgttc tttctaaaaa
     3181 caccgctttg agaaaggaaa gcatcaacca atgttgattt tccagcgtca acgtgggcta
     3241 taactgcgat atttataatt ttatgttttt gtgacatttt tgttgctccc ttcgattaaa
     3301 ataacttatt aattatagca caatatatta ttaggtacaa ggaggaatat attaaattgt
     3361 attaatatag tttaaattgg ataaaactgt tagttttgca tctgaaaatt attctgttta
     3421 aaaaaatttt ttagacaaat aataacctta atagataaaa agattaataa aagagtaaag
     3481 gatgatatat gttggaagta accaaaataa taattaaata ttttgcaagt gaaagtgata
     3541 cttttgtaaa agaagaagtt tgtaattttg aagaacttct taagtggtct cataaattta
     3601 ttgaaggtaa aaagatagaa gatgttttgt atataaagtc taaagaaaac tataaagtaa
     3661 atgtgattaa gtctttagaa attaaggaat tggaaatagt gagaaaacaa cagataccac
     3721 cgtacatgta gtattaataa tatataaaat taatatgtaa tactcgcaat aggatataaa
     3781 tggtatatat ggtaataatt tatattaaaa aaacttttat aaagtttata tttgggtata
     3841 aaagtattaa ttagacatta attaggagga acttaaatat gataagagta tgtccaaact
     3901 gttcaaatgt ggatgtaaat aagctaaaaa ctttggttgg agaagaaaat gtaaagactg
     3961 gttgtatagg tcagtgtaga gcatttaaaa aagaagctgt tggaataata gacaatgagc
     4021 ttgaaataaa ggaaacagaa gcagagtttt ttgaagcatg taaagaataa attttaaata
     4081 aaatataaat tataataaat agagcatcta aattgtataa gcattaaaca atttagatgc
     4141 tctattttta tatatacatt taattatgag tatacttttc tattaaatac aaataaatat
     4201 aactaataca tttatttatt aaaaaaatat tgatttaata tacctatagg gggtataatg
     4261 aaaatataga tttctaaata agtaatttat caatattaca tatcaaaata aaacgttaca
     4321 aattagctga aaatatattg aaagaaagga agattttatt atgagttcaa ataaagtggt
     4381 agaaagttat aaaattacag gtatgacatg tgcagcttgt gcaaaggcag tagagagagt
     4441 aactaagaag atggatggag tatatgacca aaatgtaaat atagctactg aaaaacttaa
     4501 aatagaatat gataattcta aggttaattt tgatgatata aagcaggttg tagaaaaagc
     4561 aggatatgga attataaagg aagaaagtaa taaaaaaatt gatatgaaaa ttgatggaat
     4621 gacatgtgca gcttgtgcaa aagctgtaga gagagtggta aaaaaattgg atggagtaga
     4681 aagtattagt gtgaatattg caacagataa agctaatata gactatgacc catcaaaagt
     4741 aaaattatct caaataaaag cagctattga aaaagctgga tataaaccaa tagaagaggt
     4801 aagaaataag gttgatgtgg atgaagataa attgagaaaa gaaagagaaa tgaagtcttt
     4861 atttgttaaa tttatagttg caatagtatt tgcagtacct ctgttttata tagcaatggg
     4921 acctatgata ataaagccta tagggccatg gcctttgcca gaaattataa atcctatgac
     4981 aaatactttt aattatgcat taattcagtt aattttagta ataccagtaa tgatagctgg
     5041 ttataaattt tatataaatg ggtttaaatc acttttttct ttaagcccta atatggattc
     5101 tttagttgca ataggaacat tagccgcatt tttatatagt ctatatacga cactacaaat
     5161 agccaatgga caaattcaag gtatgcacca tcatcagttg tattatgaaa gtgcaggaat
     5221 aataatagca cttatcttac ttggtaaata tttagaatca aaatcaaaag gaaaaacatc
     5281 agaagcaatt aaaaagctta tggggctaca acctaaaact gcaatagtgt tagttgatgg
     5341 taaagaagtt gaaactccta tagaagaagt agagatagga gatatactat tagtaaaacc
     5401 aggaactaaa atacccgtgg atggagttgt aatagaagga tatacatcag ttgatgaatc
     5461 aatgcttaca ggtgaaagta taccagtaga aaagaatgtt ggaagtaagg tgacaggagc
     5521 tagtattaat aaaaatggtg ttattaagtt taaggctgaa aaaattggtg gagatactgc
     5581 tcttgcccaa ataataaagt tagttgaaga tgcacaaggt acaaaagcac ctattgctaa
     5641 acttgccgat actgtatctg gatattttgt accaatagta attgcaatag ctgtagttgc
     5701 atcattattg tggtttttaa taggaggaaa agatatagta tttgtactta ctatatttat
     5761 atcagtactt gtaattgctt gtccttgtgc attaggatta gcaacaccaa ctgctataat
     5821 ggttgggact ggaaagggcg cagaaaatgg aatcttgata aaaggtggag aggcactaga
     5881 atctgcacat aaagtaaata cagtgatatt tgataagaca ggtactataa cagaaggaaa
     5941 gccaaaagta acagatatag tattaaataa taatgtaaaa gaagaatatc ttatcaagat
     6001 tgcttcaagt gcagaaaaag gttcagaaca tcctcttgga gaagcaatag ttaagtatgg
     6061 agaagagaag aatataaaat ttgaaaaagt tgataatttt aaagctatac caggtgctgg
     6121 tatacaagtt actattaatg atgaaagtat attacttgga aatagaaagc ttatgaatga
     6181 caataatata aagcttggag atttagaaga aaaatcaaat atattggcaa gccaaggtaa
     6241 aacacctatg tatatagctg tagatggaaa tttatcaggt ataatagcag ttgcagatgt
     6301 agtcaaagaa agtagtaaaa aagcaataga aatacttcat gatatgggaa taaaagttgc
     6361 aatggtaact ggagataatg cgaaaactgc aaatgctata gcaaatcaag tcggtataga
     6421 tatggttttg gcagaggttt taccagaaga taagtcaaaa gaagttgaaa aactacaaaa
     6481 tcaaggaaag tttgttgcaa tggtagggga tggaataaat gatgccccag ctcttgcaaa
     6541 agcagatata gggatagcaa taggaagtgg aacggatgta gccattgaat ctgcggatat
     6601 agtacttatg aagagtgatt taattgatgt tccaacagca attaaactta gtcatgaaac
     6661 tataaaaaat ataaaacaaa acctattttg ggcatttgga tataatacaa ttggtatacc
     6721 tgtagcagca ggaatattat atgtatttgg aggaccttta ttaaacccaa tgattgcagc
     6781 agcagcaatg agcttaagtt cagtttcagt cgtatcaaat gcacttagac ttaaaaactt
     6841 caaggcatat aagagagatt agattaataa attaaataaa atgtatccaa aagagctatc
     6901 tttaaattaa aaggattaat ttacaaatta agatagctct tttttcatgt aaaattcaca
     6961 acaataagat aaaatataag taatatacga aattttaaat aaaatagaaa ggattgatag
     7021 aatgaattcg tcaatacttg taattgaaga tgattcaaat atacaagagt taatatcaga
     7081 atttttaagt gcagaaggtt atcaagttga tacagcaaat gatgggttgg aaggtataca
     7141 aaagtttaag caaggaagtt atgatttagt aatattagat ataatgatgc caaacttaga
     7201 tggttatgga gtttgtaaaa tgataagaaa gtcatcaagc gttccaatta tatttttaac
     7261 tgctttaaat gatgaaggag accaacttaa agggtttgac ttagaatgtg atgattatat
     7321 aacaaaacca ttttcattta atcttcttat aaaaagagta gaagcaattt taaggcgaag
     7381 taacaagact ataaatgaca aatttatagt ttttgaaaaa ttaaaattag atttaaacac
     7441 atatattgca gagatagatg gagaacctat agaacttaca ctaaaagagt ttaatatatt
     7501 aaaagctttg atagaaaagt atccacaagt tataactagg gaaggtcttt tggatagtat
     7561 atggggttat gactattatg gagatactag gattgttgat gcacatataa aaaatataag
     7621 aaaaaaaata tcattaccat atattaaaac tgtaaaagga ataggatata cacttgagaa
     7681 ggatatttga taagtgggaa aagttaagta taaagtataa gttattttca ataacgacat
     7741 cattattaat agcattagct ttaataatat atctaatttt atatttttta ttgccatcat
     7801 attatcatga gtataaaatt gagtctcttc aagaaagttt gaaatcttta gtagatagtt
     7861 caattcattt cgatacatat actttagaag aaagacttta ttatatggct aaagaccaaa
     7921 atttggctat tttattaaaa gataaccaag gtaaaattgt atatggtaag aatgaagtag
     7981 ttattttaag atatagtaag tacatgatta atagtcttga ggatgagtat agaacttcta
     8041 tacctatata tactaaagat gcaaaagatg gtccatatac tttagaactc gttatgccat
     8101 tacaaccaat tgacgaagca aacgaagtta taagaaaact aatgccatac atcatatcaa
     8161 tagcaatatt gatagcgatt attggagcat atatatattc aattgtaata acaaagcctc
     8221 ttataaacat aatagagagt gagagagaac aggaatatag aaggaaggat tttgttgcta
     8281 caatatcaca tgaactaaaa actccaataa ccataataag tggtcaaatt gaaggtatga
     8341 tttatagtgt aggtaagtat aaggataggg atacttatct gaaaaaatcg tatgagtgta
     8401 cacaagaatt aaaagattta gtaaatgaaa tgatagaggt ttcaaaatca gaaatacttg
     8461 aaaaagattt gaaattggta tcaataaata taagtgaatt attaaataga cttgtaaaga
     8521 gacaagtatt tttaatagaa gaaaaacata tgaaaactat tttaaaaata gaagaaaatt
     8581 tggaaattaa agcagaccaa gagagaataa ctaaggcaat caataatata ataaataatg
     8641 ccataaaata ttctcctgaa gaatcagagc ttataattag actctatgat aaaaataaac
     8701 gaataagtaa aaagacttct aatcaaagag tggttttaga aattgaaaat actggtgtaa
     8761 ctatcgagaa acgttattta gaagaaatat ttaatccatt ttatagaata gaaaaatctc
     8821 gttcaagaaa aactggagga agtggacttg gactttatat agtcagccaa atttttaaaa
     8881 gtcatgggtt tgattatagc ataaaaaaca aagaaaactc tgtagtattc acagtagaat
     8941 ttaaaaatta attacttatt ataaagaata tataactttc aataatagtt cattttaaaa
     9001 tcacaaaaaa ttcataatga aactgtatta tataaatata aagaagctta aaaccataaa
     9061 atacaccaac tataatgatg agatttcctt acatcctcca tataagtcat cattatagta
     9121 acccaacaat taagttacta tgaatttaaa aaataacacc gagcatataa tctatgctta
     9181 gtgttatttt tattttgaaa taaaaaatat ttaatttatt gaaatgtata gatttagata
     9241 gtttaaacta tatttaagac ttaaaaatta taattgatat tacaaataaa tatatgtact
     9301 ttgggaaaaa taaatatagg aagtattata tttacagagg aggtagtttt gatggataga
     9361 ttaaaaagag atatgaaaaa tatgaaagaa gatttaaaag aaggtgttaa aaagacagct
     9421 tatgttatga aaaatacagc tgaagatttg aaagatgatg cacaaggtgc tatggtaaac
     9481 ttagaaatga aaaaagatga gatgatggaa agatatgaac aaaagaaatt ttctaaagaa
     9541 ttagagaagc aaatgaagaa tgaaatgaaa taagctttta tttatgaata acaaattatt
     9601 gtattcatat aaaaagtagc cagtaatatt aaatagttta tttaaggaaa tagactttct
     9661 aaaaataact gtattagatt tagaaagtct atttcaaatt agttttataa atagacataa
     9721 ggataaagta gatgttatag aactagattt taaaaaatag atactaagga taaaataaat
     9781 attatagaaa tatgttttta agaatattta tcaaataaaa atttatattt ataagaaatc
     9841 ctataaaaca tata
//
LOCUS       DAEPKC010000120         9769 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.121, whole genome shotgun sequence.
ACCESSION   DAEPKC010000120 DAEPKC010000000
VERSION     DAEPKC010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9769)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9769)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9769
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.121"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            324..1544
                     /locus_tag="KR294_003281"
     CDS             324..1544
                     /locus_tag="KR294_003281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH0241336.1"
                     /translation="MQQALKLKYQTKELGKDFVIESCNSIKPWLINIRRELHKIPELA
                     LEENLTKQKVISYLKEIGIDYMEFTKHNGIMAYILKESADKTICIRADMDALPIEEEN
                     NIPYKSIHSGKMHACGHDAHTTMLLGACKVLHSIKDKLNVNVKFLFQPAEEGFGGAKF
                     LVEDGCLENPKADYIFGLHVMPHIETGLIETKYDTLNASVDTIKISIKGKRAHGAYPE
                     NGIDAIVTASQIVTSLQTIISRNLEPNNAVVLTIGKIYGGDAHNVICEDVKLEGTLRT
                     LNSKTRNFMIDKIAKIVGDTASAFGCVGTLHVSDENYPAVINEKELVDTVISNTKELL
                     GEEKFILRPNPSLGGEDFSFYTEHCKGAFFHLGCKNEEKGLISPLHTSSFNIDEDCLP
                     IGVMMHVMNTLYFN"
     gene            1581..2930
                     /locus_tag="KR294_003282"
     CDS             1581..2930
                     /locus_tag="KR294_003282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBH0241337.1"
                     /translation="MEKAKKLGLFSMILLGINSIIGSGIFLLPGKVYNLAGQNSMFIY
                     IFATLLVLSILLCFAEVGSMFDKKGGAYLYSKKAFGDFIGFEVGTMSWVIRIISWSTL
                     AVGFATALGSFWPESATEYKGYIAAILVTLLSINSLFGIKSTKIMNNVITIAKLVPLI
                     VFIIVGIFFIKFVNIVPSGNVVNSSMGPAIILVFYAFTGFESFIVASGEMENPKKNLP
                     VALITTIFICAIIYILIQIVCMGILGDRLFENSIPIADASSVFVGNYGKVFISVATLI
                     SIFGINIGSSIVTPKCGSSLAEEGSLPAFIGKTNKYGAPYVAIIISLICCIPLVLTGS
                     FEQLAVMSVIARFAQYIPTCLSVIVLRKRTDVKASFKIPFGPVIPIVAILGSLWLLQQ
                     AWAEDISKPITQNRVLIGLGAMLLIAPLYIFMKKNKEIEHKNKSEDSKLYISREKIQ"
     gene            complement(3062..3355)
                     /locus_tag="KR294_003283"
     CDS             complement(3062..3355)
                     /locus_tag="KR294_003283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241338.1"
                     /translation="MISMIMMLIGVLFIVFGIILTAVEIKGKMPGFYGVGQNAVRKNA
                     IGIIAAGIALIFFRNGLDSIDSILTYGVFLVIELVVIGLYFLIRIKYDKDGNL"
     gene            complement(3841..4044)
                     /locus_tag="KR294_003284"
     CDS             complement(3841..4044)
                     /locus_tag="KR294_003284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241339.1"
                     /translation="MSFGKRIEMNNIGVETRGVCTIMCPYTCKMMASSSCNCKNNDYN
                     ARGGSYNTYYNKLIHGQRTPDGM"
     gene            complement(4095..4346)
                     /locus_tag="KR294_003285"
     CDS             complement(4095..4346)
                     /locus_tag="KR294_003285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide maturation system acyl carrier-related
                     protein"
                     /protein_id="HBH0241340.1"
                     /translation="MNYTEKELLLENIFFDVTGINFNKNNNLKKELFFSPSLHIQPRE
                     LLLVFCEVIENFNIKIPEEKLLNRQFTSFDNVLKIINMV"
     gene            complement(4362..5432)
                     /locus_tag="KR294_003286"
     CDS             complement(4362..5432)
                     /locus_tag="KR294_003286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04066 family peptide maturation system
                     protein"
                     /protein_id="HBH0241341.1"
                     /translation="MEKVLIYPFNYNFFTILNHCNKISDIEINSLVSPSGWGLCNKEY
                     NVNNIITKVTNDFQSELKKNSLVWFVDSKENLDLEKFIIPKLKVALKEGKKILYTRDD
                     LNKISRYISHYEFKKINEWNLEKYEIRDIEGISQINTPIIFICGLYGGLDTFDVNIRI
                     GEELRKRGFSILQFGPKKESYLFKMIPIPEFMFDDSISSKTKIINFNHFIKDKEVEAK
                     PDLIIIEVPGELFPFSRKMVGNFGIRAFEISNAVINDCGILCIPSSIYDREYCEELKY
                     FIKGRHGINIDYFSIEKKVIDTYETEVKQKFSYMSLDENFFVEDIEDYEKTFFIHDNK
                     QLLELVDNIVNQLKEYAKVISI"
     gene            complement(5461..6882)
                     /gene="ccpM"
                     /locus_tag="KR294_003287"
     CDS             complement(5461..6882)
                     /gene="ccpM"
                     /locus_tag="KR294_003287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-rich peptide radical SAM maturase CcpM"
                     /protein_id="HBH0241342.1"
                     /translation="MNQKPFIHTFKAGKSYFIYDVNTDKILKVNAAVYNYLNKIEHNL
                     EKESDWNIEIEDEINTLINYGFLKNKRVSKTMHPETKYIKYHIENNLSSIILQVTQNC
                     NLRCDYCIYSGSYSNRVHTNKRMNIDVAKRSIDYLIKNSSQLNEVSVGFYGGEPLLEF
                     DLIKQIVEYVKVVGEGKEIYFNLTTNATLFNEEIIEFFVKNNITTMISLDGGKEIHDK
                     SRKFANTGEGSHDVVLKNVRYIKNKYPEYYKKNITFNTVINSENDYISIDDFISKNET
                     LKDSNFLASTLNNNYSDKEIVSSDEYILGKSYDRFLTLLNKLKFIKDESMSPLSRIER
                     ALLDDFRYEKNIEGRLELPDVWHHGGPCIPGAFRIFVTTDGEFFPCERVSESSKMGMI
                     GNLDSGVDIEKAEKLLNIGKLYEEQCSDCWAYSYCDICIAKIDDTKCNENEIKPHDCD
                     RIRHSTENNMKDYCVLKSLGYQY"
     gene            complement(6904..8676)
                     /locus_tag="KR294_003288"
     CDS             complement(6904..8676)
                     /locus_tag="KR294_003288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0241343.1"
                     /translation="MENGKFQFFKGVRNCFNMIYLHDKRYLFISMFMAIFQGIVPSIS
                     LLVSQNIINNMQTFSKSVKEILVLLIMYLIINIIPSIFQSFYGYYRIKFNKNFEKHIE
                     TMMLEKSLTLSLKDFEDDNTYDMINRAQSQKGFNITILSENLISIIRESVSTLSLIVV
                     LSQFQLWLIIVVIVIPVLKSLYSIKLGKEQYDVSVNRTWKERKAWYIDYLLSKGYAYK
                     EIMVFRIGSKLINHYKKLKEDIISQDMNIAKKNFIATLLCTVLDSIVSAGIIGFIIIQ
                     GILKKILIGDATTYIQAVQSIKDNVESIFSLFSSVIQDLFYTDLLFKFLDYNCKEDSI
                     EHIKIFEKIGDINKIELINISYKYNHSSEYSLKNINLTLNKNDPIAILGKNGSGKTTL
                     LKILLGFYDDYEGDILINGKNLKDIEKDEYIRKVSCMFQDYIKYEATLKENVAMGDVY
                     KSNLEEKVKSKLKETKLKPSIYEEDGLETILGTWFGKKQLSMGEWQKVAISRTLMKDA
                     DMYIFDEPDSSLDSEAGNELLSLYKKTFENKIGIFITHHIQHAKKITNNIVVLENGKL
                     LESGRHDELMDKKGVYFNLFCNCK"
     gene            complement(8949..9662)
                     /locus_tag="KR294_003289"
     CDS             complement(8949..9662)
                     /locus_tag="KR294_003289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0241344.1"
                     /translation="MINIIICEGKKSERVILNDYINTFFYNYNFEYNIKEFENGGDLL
                     KKYPNNVDIIFMDIDLNDENGFNVSKEIKKFDESVRIIFVSSSNKYIKKGYEIGVYRY
                     LEKPLKYSLFKEAISSYLKECYKNEAILSIKCKCKIYFIKVDDILYLEVLKNDLTIHT
                     EKGIYTFKSSMKEIESNLEEHNFFRCHKSYLINLMKVNMLDIENNIVFINQNSIIVSR
                     YKIKLLREKLNSCLVDVII"
BASE COUNT         3535 a         1410 c         1022 g         3802 t
ORIGIN      
        1 tccttcaata ggttttttta tttttcaagt accctaaaat tataatttat tttgtacata
       61 aataatagga attaatagga ataggataat ttttttattt cctatttttt ttatataaac
      121 tagcatataa aatatatttt cttcaaaata atatttttta ctgaaaattg aaactatgca
      181 atcatttttt atactataca tatagataaa tgattatatt tattcaatat tcttataaaa
      241 aacaaaattc tccatcgaaa attatggcat aataattgct tattatatta ataaaacaat
      301 aaaaagcaat tggaggaata aaaatgcaac aggctttgaa attaaaatat caaaccaaag
      361 aattaggaaa agattttgta atagaaagtt gtaattctat aaaaccatgg cttataaaca
      421 taagaagaga attacataaa attccagaat tagctcttga agaaaatctt actaaacaga
      481 aggtaatttc ttatttaaaa gaaatcggaa ttgattatat ggaatttaca aaacacaatg
      541 gaattatggc atatatttta aaagaaagtg cagataaaac gatttgtata agagcagata
      601 tggatgctct tcctattgaa gaagaaaaca acatacctta taaatcaata cattctggaa
      661 aaatgcatgc ttgtggccat gatgcacata caaccatgct acttggagca tgtaaagttt
      721 tacattcaat aaaagataaa cttaatgtaa atgtaaaatt cttatttcaa ccagcagaag
      781 aaggttttgg aggagcaaaa tttttagttg aggatgggtg tttagaaaac cccaaggccg
      841 attatatatt cggacttcat gttatgccac atatagaaac aggccttatc gaaacaaaat
      901 atgatacatt aaatgctagt gtagacacta taaaaataag tatcaaaggt aaaagagctc
      961 atggtgcata tcctgaaaac ggtattgatg caatagttac agcttcacaa attgttacat
     1021 cattacaaac tataataagt agaaacttag aaccaaataa tgctgttgtt ttgactatag
     1081 gtaaaatata tggtggtgat gcacacaatg taatatgtga agatgtaaaa ttagaaggca
     1141 ctttaagaac cttaaatagc aaaacaagaa actttatgat tgataaaata gctaaaattg
     1201 ttggagatac tgcatctgca tttggttgtg ttgggacttt acatgtaagt gatgaaaact
     1261 atcctgctgt tataaatgaa aaagaattag tagatacagt tatatcaaat actaaagaat
     1321 tacttggaga ggaaaaattt atattgagac caaacccgtc tttaggtggt gaagactttt
     1381 ctttttacac agaacattgt aaaggagcat tcttccattt aggatgtaaa aatgaggaaa
     1441 agggcttaat ttcacctctt catacctcta gctttaatat agatgaagat tgtttaccaa
     1501 taggtgttat gatgcatgta atgaatactt tgtattttaa ttagtacagt aattaataaa
     1561 agaataggag ataaattaat atggaaaaag ctaagaaatt aggtctattt agtatgatat
     1621 tattagggat taatagcata ataggttcag gtatattctt actaccaggt aaagtttata
     1681 atctagcagg tcaaaacagt atgtttatat acatttttgc tacactctta gttctatcaa
     1741 tacttttatg ttttgcagaa gttggaagca tgtttgataa gaaaggagga gcatatctat
     1801 actccaaaaa agcttttgga gattttatag gatttgaagt tggtacaatg tcttgggtta
     1861 ttagaattat atcatggtct actctagcag taggatttgc aacagcttta ggttcatttt
     1921 ggccagaatc tgccactgaa tacaaaggtt atatagctgc aatactcgta acactacttt
     1981 caataaatag cttatttgga attaaaagca caaagataat gaataatgta ataactatag
     2041 ctaaattagt accattaata gtttttataa tagttggaat attttttata aaatttgtaa
     2101 atattgttcc ttcaggaaat gtagttaact ctagtatggg tccagccatt atattagtat
     2161 tttacgcatt taccggcttt gaatcattta ttgtggcaag tggagaaatg gaaaatccta
     2221 aaaaaaatct tccagtcgca ttaataacca caatatttat atgtgcaata atttatatat
     2281 taattcaaat tgtctgtatg ggtatacttg gagatagact atttgaaaac agtattccaa
     2341 ttgcagatgc ttcaagtgta tttgtaggca attatggtaa agttttcata tctgtagcaa
     2401 cattaatatc tatatttggt ataaatatag gttcatcaat agtaactcct aaatgtggtt
     2461 cttctctagc agaagaaggt tctcttcctg catttatagg aaaaacaaat aaatatggtg
     2521 ctccatatgt agcaataata atatctttaa tttgttgtat accacttgtg ctaactggaa
     2581 gttttgaaca acttgcagta atgagcgtaa ttgcaagatt tgctcagtac ataccaactt
     2641 gtttatcagt aatagtttta agaaaaagaa cagatgttaa ggcctctttt aagattccat
     2701 ttggccctgt tataccaata gtagctattt taggtagctt atggttgtta caacaagctt
     2761 gggcagaaga tatttcaaaa cctataactc aaaatagagt tttaatagga ttaggggcaa
     2821 tgttgttaat agctcctcta tatatattta tgaaaaaaaa taaggaaatc gagcataaaa
     2881 ataaatcaga agattctaaa ttatatattt cgagagaaaa aattcaataa tattttatac
     2941 tattacttct cataaaatat aataaatata aaaaaattgt agataaaact attttataaa
     3001 atttatctac aattttttta tataaacata tatcaaaatc aaaatattat taatttatac
     3061 tttaaagatt cccatcttta tcatatttta ttcttataag aaaatataat cctattacta
     3121 ctaactctat cactaaaaat actccatagg taagaattga atcaatacta tctaacccat
     3181 ttctaaaaaa aattaatgct atacctgctg ctataatccc tatagcattt tttcttactg
     3241 cattttgccc aactccataa aaacctggca tttttccttt tatttcgaca gcagttaaaa
     3301 ttatcccaaa cactataaat aatactccaa taagcatcat aatcatacta atcatctaat
     3361 tacctccttc acttaaggaa atttcaattt ctaaaatcta aaataaataa tatttatttt
     3421 ttataataat attgtatatc caattaacta ttttggaaat tagtaccaat aaataatgtt
     3481 taaatattga aataatatat taattctaat caatattatt aatatatata tacattttta
     3541 caaatatatt taaaaacttt acttttaatt cttactattt aaataagtat aatttattat
     3601 aataactttt aattaattta tacttttaaa ttgtaaaaat cacccctaat cactatattt
     3661 accactataa taattgaaga ggtgatttat ataacagata ctatttatgc agttattata
     3721 aaatcacact cttaattata atcaactgca tatttttata ataaaaggaa ataaagtaag
     3781 aaagataaat ttaatcaaat atgctaaatc aatttaatag tatacttatt actgaaatat
     3841 ttacattcca tcaggagttc tttggccatg tatcaattta ttataatatg tattatatga
     3901 tcctcctctt gcattataat cattattctt gcagttacaa gatgaagatg ccatcatctt
     3961 acaagtataa ggacacataa tagtacaaac acctcttgtc tcaacaccta tattattcat
     4021 ttctattctt tttccaaaac tcattcatat cctccccttt tctataagat cacttacttt
     4081 atacctttat taacctatac catattgatt atttttagaa cattatcaaa actcgtaaat
     4141 tgcctattca aaagtttttc ctctggaatt tttatattaa agttttctat tacctcgcaa
     4201 aatactaaaa gtaattctct tggctgtata tgtaaagacg gtgaaaaaaa taattctttt
     4261 tttaaattgt tatttttatt aaaattaatt ccagtcacat caaaaaatat attctctagt
     4321 agtaattcct tttcagtgta attcataatt aacctccaat tctaaataga tattacttta
     4381 gcatactctt ttaattgatt cactatattg tccactaatt ctagtaattg tttattatca
     4441 tgtataaaaa atgttttttc ataatcttct atatcttcaa caaaaaagtt ttcatctaat
     4501 gacatatatg aaaatttttg cttcacctct gtctcatatg tatctataac ttttttctct
     4561 atactaaaat agtctatatt tataccatgt cttcctttaa taaaatattt aagttcttca
     4621 caatattctc tatcatatat acttgatgga atacataata taccacaatc atttattact
     4681 gcattagaaa tttcaaaagc tctaattcca aaattaccaa ccatttttct agagaaaggg
     4741 aataattctc ctggaacttc tataattatt aaatctggct ttgcctctac ctctttatct
     4801 tttataaaat ggttaaaatt aataatcttt gtcttactac ttatcgaatc atcaaacata
     4861 aactctggta taggaatcat tttaaataaa tagctctctt ttttagggcc aaattgtaat
     4921 attgaaaacc ccctttttct tagttcttct cctatcctta tatttacatc aaaagtatct
     4981 aaccctccat aaagaccaca aataaatatt attggtgtgt ttatctgtga tataccctct
     5041 atatctctta tttcatattt ttctaaattc cattcattaa tctttttgaa ttcataatga
     5101 gatatatacc tagatatttt attaagatca tcacgtgtat ataatatctt tttaccttct
     5161 tttagagcta cttttaattt aggaattata aatttttcta agtctagatt ttcttttgaa
     5221 tcaacaaacc ataccaaaga attcttttta agttcacttt gaaaatcatt tgtaacttta
     5281 gtaataatat tattaacatt atactcctta ttgcataacc cccagccaga aggactaacc
     5341 agtgaattaa tttctatatc tgaaatttta ttgcaatgat ttaaaatagt aaaaaaatta
     5401 taattaaatg gatatataag tactttttcc ataatcccat ctttcctttc attagaaaat
     5461 ttaatattga tatcctagag atttcaaaac gcagtaatct ttcatattat tttctgtaga
     5521 atgtctaatt ctgtcacaat catgtggttt tatttcattt tcattacatt tagtatcatc
     5581 aatcttagct atacatatat cacaataact ataggcccaa caatcagaac attgctcttc
     5641 atataatttt cctatattta aaagtttttc agccttttct atatctactc cactatctaa
     5701 atttccaatc atacccattt tagaactttc acttactctc tcacatggaa aaaattctcc
     5761 atctgtagtt acaaatattc taaaagctcc tggtatacat ggtccaccat gatgccacac
     5821 atctggtaac tctaatctac cttcaatatt tttctcatat ctaaaatcat ctaataaggc
     5881 tctttctatt cttgataaag gtgacatact ctcatctttt ataaatttta atttgttgag
     5941 taaagtcaag aatctatcat aactcttacc taatatatat tcatctgatg aaactatttc
     6001 tttatcagaa tagttattat taagagtgga agctaaaaag tttgaatctt ttaaagtctc
     6061 atttttagat ataaaatcat ctatagaaat gtaatcattt tctgaattta tcactgtatt
     6121 aaatgtaata ttctttttat aatattctgg atatttattt tttatgtaac gtacattttt
     6181 taatacaaca tcatgagatc cttctcctgt atttgcaaat tttctacttt tatcatgaat
     6241 ttcttttcct ccatctaaac taatcatagt tgttatatta ttttttacaa agaattctat
     6301 tatttcctca ttaaataaag ttgcatttgt agttagatta aagtatattt cctttccttc
     6361 tccaactact tttacatatt ctactatctg cttaatcaaa tcaaactcaa gtaagggttc
     6421 tcctccataa aagccaacac taacttcatt taattgacta gaattcttaa tcaaatagtc
     6481 aatacttctt tttgctacat ctatattcat tcttttattt gtatgaactc tgttgctgta
     6541 tgaaccagaa taaatgcaat agtcacaacg taaattacaa ttttgggtta cttgtaaaat
     6601 aatagaggat agattatttt ctatatgata ttttatatac ttagtttcag ggtgcattgt
     6661 tttacttacc cttttatttt ttagaaatcc ataattaatc aaggtattaa tttcgtcttc
     6721 tatttctatg ttccagtcac tttctttttc taaattatgc tcaattttat ttagataatt
     6781 ataaacagca gcatttacct ttaaaatctt atccgtatta acatcataaa taaaatatga
     6841 ttttccagct ttaaatgtgt gtataaatgg tttttgattc attaattaac ctccctttaa
     6901 tatttatttg cagttacaaa ataaattaaa ataaacaccc tttttgtcca taagttcatc
     6961 atgtcttcca ctttctaaca actttccatt ttcaagaact acaatattgt tagttatctt
     7021 ttttgcatgt tggatatggt gcgttataaa tattccaatc ttattttcaa atgttttttt
     7081 atataaagaa aggagttcat ttcccgcttc agaatctaaa gatgaatctg gttcatcaaa
     7141 aatgtacata tcagcatctt tcataagagt tctagatatt gctacttttt gccattcacc
     7201 catagaaagt tgcttcttac caaaccaggt tcctaaaata gtttctaatc catcttcctc
     7261 ataaatactt ggtttcaatt tagtttcttt aagtttactt ttaacttttt cttccaagtt
     7321 actcttatat acatctccca tggcgacatt ttcttttaat gtagcctcat atttaatata
     7381 atcttgaaac atacaactta cttttctaat gtattcatct ttttcaatat cctttaaatt
     7441 ttttccattt atcaagatgt caccttcata atcatcataa aaacctaata atatttttaa
     7501 aagtgtcgtt ttacctgaac cattttttcc tagtatagca atgggatcat ttttatttaa
     7561 agttaaatta atatttttta aagaatactc tgatgaatga ttgtatttat atgaaatatt
     7621 tattaactct attttattta tatcccctat tttttcaaat atttttatat gttcaattga
     7681 gtcttcttta cagttataat ctagaaattt aaacagtaaa tctgtataaa aaagatcttg
     7741 tattactgaa ctaaataacg aaaatattga ttcaacatta tcctttatag attgaactgc
     7801 ttgtatatat gtagtcgcat ctcctattaa aatcttcttt aaaatacctt gaattattat
     7861 aaatcctata attcctgcag atacaattga atctaaaact gtacataata gcgtagcaat
     7921 aaaattcttt ttagctatat tcatatcttg agatataata tcctctttta attttttata
     7981 atgattaata agtttagaac caattctaaa taccataatc tctttgtaag cataaccttt
     8041 tgacaacaaa taatctatgt accaggcctt tctttctttc caagttctgt ttacactaac
     8101 atcatattgt tcctttccta atttaatgga atataatgat ttcaatacag gaataacaat
     8161 aacaactatt attagccaaa gttgaaattg tgataataca acaataagag aaagtgtaga
     8221 tactgattct cttattattg aaataaggtt ttcagatagt atagtaatat taaatccttt
     8281 ttgagattga gctctattta tcatgtcata agtattatca tcctcaaaat cttttaaact
     8341 caaagttaaa gatttctcta acatcattgt ttcaatatgt ttttcaaaat ttttattaaa
     8401 ctttattcta taatatccat aaaaactttg aaaaattgaa ggaattatat ttatgattaa
     8461 atacataatt aacaaaacta atatttcttt tacacttttc gaaaatgttt gcatattatt
     8521 aatgatattt tgacttacta acaaagaaat agatggaaca atcccctgaa aaattgccat
     8581 aaacatagag ataaataaat atcttttatc atgtagataa atcatattaa aacaatttct
     8641 tacaccttta aaaaattgaa atttaccatt ttccacaata cacctccata cttaataaaa
     8701 ttgaaataaa atattttatt aattaatata atataacatt attttattat gtataataca
     8761 tatttaaatt ttaaattaaa tctttaaaat aaaattgtta atagaattgt aaaataaaat
     8821 cttaatatat tcaatctgtt attgatgaaa ggtatatttt taactataat tagtttttat
     8881 tataaatttt ttcatatttt acaatagata tattctatta gaatagaata taaaggcaaa
     8941 aatttacctc aaattattac atctaccaaa caactattta acttttctct caataatttt
     9001 atcttataac gacttacaat tattgaattt tgatttataa atacaatatt attttctata
     9061 tctagcatat ttaccttcat taaatttata aggtagcttt tatgacatct aaaaaaatta
     9121 tgttcttcta gatttgattc tatttctttc atactactct taaaagtata tattcctttt
     9181 tcagtatgta tagttaaatc attttttaaa acttctaaat ataaaatatc atctaccttt
     9241 atgaaatata tcttgcattt acattttata gataaaatag cttcattttt gtagcattct
     9301 tttaaatatg atgatattgc ttctttaaat agagagtatt ttaagggctt ctctaaatat
     9361 ctataaactc ctatctcata acctttcttt atgtatttat ttgatgagga tacaaatata
     9421 attcttacac tttcatcaaa ttttttgatt tcttttgaaa cattaaatcc attttcatca
     9481 tttaagtcta tatccataaa tatgatatca acattattag gatacttttt taataaatcg
     9541 cctccatttt caaactcttt gatattgtat tcaaaattgt aattataaaa aaaggtattt
     9601 atataatcat ttagaattac cctctctgat tttttacctt cgcaaataat aatattaatc
     9661 atattacacc ccttatataa ttttttattt taaattttat aaaattctat ctaacattta
     9721 ttatatttca aatttaaaga tattttttaa tacaaaattt ttgtataat
//
LOCUS       DAEPKC010000121         9618 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.122, whole genome shotgun sequence.
ACCESSION   DAEPKC010000121 DAEPKC010000000
VERSION     DAEPKC010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9618)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9618)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9618
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.122"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            231..1310
                     /locus_tag="KR294_003290"
     CDS             231..1310
                     /locus_tag="KR294_003290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HBH0241345.1"
                     /translation="MPELLKNMYNRESLYEVAVAIQSVYNSFKVDEFIKSTMDETWNN
                     LELKARCRKISMSLGMYLPEDYKEALSILEKSVTGFYFAFFFPDFVEVYGQDDINWDL
                     SISALERNTEYWSSEFAVRAFIIKDEERMMAQMRKWSKHKSEHVRRLASEGCRPQLPW
                     GQAISKFKKDPTPVLPILEQLKTDTSTYVQKSVANNLNDISKTHPDLVISIAKDWYGK
                     NKSTNWIVKHGCRTLLKKGNRDVLALFGYDDTTSINLQDFTLETTSISIGEDLTFSFN
                     ILAKKATKTRLEYGIDYIKSNGKRNRKIFKISEVSLKENEKKSYMKKHSFADVSVRKH
                     YPGIHSIAIIINGIEKDKLDFELGI"
     gene            1634..2002
                     /locus_tag="KR294_003291"
     CDS             1634..2002
                     /locus_tag="KR294_003291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HBH0241346.1"
                     /translation="MDVYSFWNDTLAQDAVKIRKYFHENAYINWHDTNEHFTLEEFII
                     ANCEYPDKWNGKVEKVLEFGNLVITVTHVYAINKPLSFHVVSFISLKDDKIISIDEYW
                     GEDNDVPQWRLDKHIGKPIK"
     gene            2119..2922
                     /locus_tag="KR294_003292"
     CDS             2119..2922
                     /locus_tag="KR294_003292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBH0241347.1"
                     /translation="MEEKYILSDRGKVYYWIKESNSVFAKNLIFLPGLTANHHLFDFQ
                     IQYFSKNHNVLVWDAPAHGKSRPYLDFSYSNLVEELKVILDKQNMKKVVLIGQSAGGF
                     VAQSFIVKYPNMVEGLMMIGTCPYGTDYYSKSDIFWLKQTEWMLKLFPDKFLRNIISK
                     MCGATSEGRRSMMKMLEGYEKKELCHLMYLGFAGFIPEIQDLNIHCPVCLVVGDKDKT
                     GKVRKYNEQWHNKTGYPLHIIKNASHNVNVDKPNELNQIMDIFIKQLNI"
     gene            3307..4197
                     /locus_tag="KR294_003293"
     CDS             3307..4197
                     /locus_tag="KR294_003293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBH0241348.1"
                     /translation="MIESIPAKQILQKVKFDNTRWFGIDYNMNLYRGCSHGCIYCDSR
                     STIYNIENFDKVRYKENVIEILSKELRSKRKKGVVGIGAMSDTYNPFEKQLCITKQAL
                     DLISENHFGVSIDTKSSLVVRDIPILQKIKKNNSAIVKLTITTANDELSKKIEPYVNP
                     SSVRFEAVKELNDSGIFCGILLTPMLPFLTDTKDEIRAIVEKAHKANAKFIYCMYGVT
                     MRSGQREFFYEHLRDISPKLVFKYQKTYGLNYVCTVQNKDCCEKLLREECARYGILTD
                     MKDIIKAYKRSESYTQIKFF"
     gene            4660..5103
                     /locus_tag="KR294_003294"
     CDS             4660..5103
                     /locus_tag="KR294_003294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH0241349.1"
                     /translation="MIEIKTIEINKKSQIDLLILADPCEEMIDKYLNKGTMYALYDNK
                     ELTCIAVVNEISKEICELKNIATYEHFQNMGYASKMIYHLLDVYSKKYSSMVVGTSES
                     GVPFYEKFGFVYSHKIKNFFVDNYPEPIFEGELQCVDMLYLSYNF"
     gene            5275..5445
                     /locus_tag="KR294_003295"
     CDS             5275..5445
                     /locus_tag="KR294_003295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241350.1"
                     /translation="MDSNNNTIKSTVKKGISFGSCLAMIISYTAWKSIPWAIFHGLMS
                     WIYVLYYWVKYA"
     gene            5818..6939
                     /locus_tag="KR294_003296"
     CDS             5818..6939
                     /locus_tag="KR294_003296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HBH0241351.1"
                     /translation="MKEKLEEKSKIIKTSKEYKRTIIEEKDREWTQKLNDILSRGDFS
                     NEKLDKIKDLIPKEILTSENVGEVVTEDGYAKPEYDEVFKSLFTLNNDYDLLANFIND
                     ILKDAPYANRNIKQFTQIKRIIKVETDPTINYIGEKRPRLDILAEDEERNHINIEMQR
                     ALEEDYLERAEYYLSRVHGRKLEEGKEYKEIGKTVGIHILNHVKYNHIEDYVNCLRLT
                     MDGHPDIFSSKTALYFIELPKIRKSSCIANRVLIWGKLIDNPSHIDIRILSKTDYVIK
                     RALDRLKELGSNEDYLLNLKRGAYIMNKSRNFKEEIFQEGIEKGIEKGIEKGIAKGKR
                     EEKFNIIIKLKNKGYNLSEICDIIDDLNKSEVEKVYNQN"
     gene            7144..7632
                     /locus_tag="KR294_003297"
     CDS             7144..7632
                     /locus_tag="KR294_003297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3841 domain-containing protein"
                     /protein_id="HBH0241352.1"
                     /translation="MKFYTIQTLEFWNNNKNNKYLSNDYSFILEDFDIPYKWMYSQMT
                     NRIYEFDDSMIWVWTKRPDLRCSGYLEKGKKGVLLEIEISEDNVLLSEFDLWHLPLMD
                     ITVELYEDEQIEKKVSWERIFDLELCSKLNEVNIEDLTLQGVTSKVPLSNVKLIKEFV
                     AK"
     gene            7718..8125
                     /locus_tag="KR294_003298"
     CDS             7718..8125
                     /locus_tag="KR294_003298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241353.1"
                     /translation="MSKQQTGIKSTLISEILGISYCIGATLVNKYFFKGSSIEYLPII
                     IWVLAMGAQWVYNKKYDDLIDEASKCILSRVNDIAIKVLFFSVAIVSIFLVTLDINVS
                     NLNIGMSLLVILFIQSLLKLILFIYFDRKGIYN"
     gene            8126..8344
                     /locus_tag="KR294_003299"
     CDS             8126..8344
                     /locus_tag="KR294_003299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0241354.1"
                     /translation="MSVLLKTKIKSYREKNLMTQGELAKSVGVRRETIVHLENGRYNP
                     SLKLAMDIAKVFDTTVEELFEFIEENNI"
     gene            9418..9618
                     /locus_tag="KR294_003300"
                     /pseudo
     CDS             9418..9618
                     /locus_tag="KR294_003300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427875.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         3860 a          925 c         1658 g         3175 t
ORIGIN      
        1 cagtaaagta taaaattcta ttactataat aaaagataga actagaagtc tttatgaaag
       61 tgggaaaagt atttatataa ataaattcat atagtttata gtttaatagt aggaaatatc
      121 gtatgagtaa gaatattgta ttttacataa agatttagca atatgacaca ctgttgtcgt
      181 gttctgtagg atatgattaa taaatcagat atgaaaggag agtgagtaat atgccagaat
      241 tactaaaaaa tatgtataat cgtgagtcac tttatgaagt tgcagtagct atccaatcag
      301 tttacaactc atttaaggta gacgagttca taaaatctac aatggatgag acatggaata
      361 acttagaatt aaaagccaga tgtcgaaaga taagcatgag tttaggaatg tatttaccag
      421 aagactataa ggaagctctt tccattcttg aaaaatcagt tacaggtttt tattttgctt
      481 ttttctttcc agattttgtt gaagtttatg ggcaggacga cataaattgg gatttatcta
      541 taagtgcatt agaaagaaat actgagtatt ggtcttcaga atttgctgta agagcattta
      601 tcatcaagga tgaagaacgt atgatggcac agatgcgtaa atggtctaag cataagagcg
      661 aacatgtacg aagacttgca agtgaaggtt gtcgtcccca gttgccttgg ggacaagcaa
      721 tatccaaatt taaaaaagac cctacacctg tgctacctat attggagcaa cttaaaacag
      781 atacatcaac gtatgtacaa aagagtgttg ctaataatct aaatgatatc tcaaaaacac
      841 atccagattt agtcataagc attgcaaagg attggtacgg taaaaataaa tctactaact
      901 ggattgtaaa gcatggttgt agaactctac taaaaaaagg aaatcgtgat gtattagccc
      961 tttttggata tgatgatact acttctataa atcttcagga ctttacttta gaaacaacgt
     1021 ctatttctat tggagaggat ttaacttttt catttaatat tttagcaaaa aaagcgacaa
     1081 aaacaaggct cgagtacgga attgattata ttaaatctaa tggaaaaagg aataggaaga
     1141 tatttaaaat atcggaggtt tcattaaaag aaaatgagaa aaagtcatat atgaaaaaac
     1201 attcatttgc agatgtaagt gtaaggaaac attatccagg tatacactcg attgctatta
     1261 ttattaatgg tatagaaaaa gataaacttg attttgaatt aggtatataa ttttactaac
     1321 agaataatct atatcagata ctttgctaaa cttatataat atattttact aaatttatat
     1381 taggtagttt actacttgtt tactgaattt aaatacaaag aaatacaggt gctaatccct
     1441 gcccattaaa ggaatatgag cataacacaa aagtagaact tatcaattct gttacgggta
     1501 tagtagtaaa tccatagaat cacaattaga agatgaagtg taaaaaataa gttagtgttg
     1561 attttagttg ctagtgatat tgaatagtta tacaatagct atataaatta gaatttgtag
     1621 aggagaaatg taaatggatg tatatagttt ttggaatgac actttagcac aagatgctgt
     1681 taagataaga aaatattttc atgaaaatgc ttatattaat tggcatgata caaatgagca
     1741 ttttacttta gaagaattta ttattgcaaa ttgtgagtat cctgataaat ggaatggtaa
     1801 agtagaaaag gtgctagaat ttggaaattt agtaattaca gtgacacatg tttatgcaat
     1861 aaataaacca ctatcatttc atgtcgtttc atttatcagc cttaaagatg ataagattat
     1921 ttctattgat gaatattggg gagaggataa tgatgtgcca cagtggagat tagataaaca
     1981 tattggaaag ccaataaaat agtttttgtt ctgttttata actgaaattt tgataacatt
     2041 tgatattttg atttgtcatt ggtcaacata gtcgttagtg taataattta aaaaagtaga
     2101 atttggagag tgaacactat ggaagaaaaa tacatcttat ctgaccgagg gaaagtatat
     2161 tattggataa aagaaagtaa tagtgtgttt gcaaagaact taattttttt gccaggacta
     2221 acagcaaatc atcatctttt tgatttccaa atacagtact tttcaaaaaa tcataatgta
     2281 ttggtatggg acgctcctgc tcatggaaaa tcaagacctt acttagattt ctcatattct
     2341 aacttggtag aagaattgaa agtaatttta gataaacaaa atatgaaaaa ggttgtactt
     2401 atagggcaat cggcaggggg atttgtggca cagtccttta ttgtaaaata tccaaatatg
     2461 gtagaaggac taatgatgat tggaacttgt ccatatggaa ctgactatta tagtaagtca
     2521 gatattttct ggttaaaaca gactgaatgg atgttaaagt tattcccaga taaatttttg
     2581 cgaaacataa tatctaagat gtgtggagct acgtctgaag gcagaaggag tatgatgaaa
     2641 atgttagaag gctacgaaaa aaaagaactg tgtcatctca tgtatctggg atttgctggg
     2701 ttcataccag aaattcaaga cttaaatata cattgtccag tttgtttggt ggttggagat
     2761 aaagacaaga cgggtaaagt gagaaaatat aatgagcagt ggcacaacaa gactgggtat
     2821 ccattgcaca ttataaaaaa tgcttcacat aatgtaaatg tcgataaacc taatgaacta
     2881 aatcagatta tggatatatt tattaagcaa ttaaatatat aaaaattaca tactcattag
     2941 gtaaattatg tagtatatgt gtttatagat ggttatagaa ataaatatgt aataaactac
     3001 ttaacactta aaaagtggat ttgtccagag cataatacaa agcatgatat ataaattttt
     3061 aagcgaaata catcaaaaga agtattagaa ttagtggaga taaaacagct attagagatt
     3121 ataaataaat agttttaaag gtactacgaa tatagaggaa ggtaaatcat acgttattca
     3181 aggattataa atgattagtt taaaagtact atcggacagg tctctgcata tttaaacctt
     3241 agtaaaggta gttaaagtag tagtttaaaa actaaaaaat tatataaagg aattaggtat
     3301 aagaaaatga ttgagagtat accagcaaaa caaattttac aaaaagtgaa atttgacaat
     3361 acaagatggt ttggaattga ctataatatg aatctctatc gtggttgttc tcatggatgt
     3421 atatattgtg atagccgtag cacaatatac aacatagaga attttgacaa agttagatat
     3481 aaagaaaatg tgatagagat tttaagtaaa gaattgcgtt caaaaagaaa aaaaggggta
     3541 gtaggcattg gagctatgtc tgacacatat aatccttttg aaaagcaact ttgtattaca
     3601 aagcaggcac tagatttgat ttcggaaaat cattttggag tgtctattga tactaaaagt
     3661 agtttggtgg ttagagatat accgattttg cagaaaatta aaaaaaataa ttctgctatt
     3721 gtaaagttga ctataaccac tgcaaatgat gaattatcaa agaaaataga accttatgta
     3781 aatccaagtt ctgtacgatt tgaggcagtg aaagaactta atgattctgg aattttttgt
     3841 ggtatattat tgactcctat gcttccattt ttgactgata ctaaagatga aatacgagca
     3901 attgtagaaa aagcacacaa ggctaatgca aaatttattt attgtatgta tggtgtaaca
     3961 atgcgtagtg gtcagcgaga gtttttttat gagcatttaa gagatatatc accaaaattg
     4021 gtatttaaat atcagaaaac atatggttta aactatgtat gtactgtaca aaataaagat
     4081 tgttgtgaga agttgttaag agaagaatgt gcacgttatg gtattttgac ggatatgaaa
     4141 gatattataa aagcgtacaa gaggtcggag tcatatactc aaataaaatt tttttaagat
     4201 aggctttgga tgagatataa tagtggtgat tgatgtgttg atattatagt tgattgttag
     4261 agaggatatt atagatgaat attagtatta atattttagg taattgctag agctgatatt
     4321 atagatgaat attaatattg atattctagg taattgctag agttagtatt atagatgaat
     4381 attagtattg atattttagg taattgctag agctgatatt atagatgaat attaatattg
     4441 atattctagg taattgctag aactaatatt atagatgaat attagtattg atattctagg
     4501 taattgctag agctgatatt ataatttatt attaatatta atattctagg gaattatcac
     4561 tatattttaa aaagtaaaaa tatatatcaa aatgaactaa ataagtactg taagaagttt
     4621 gttaaattaa ggtttgaata aagtgagggt ggagaactta tgatagaaat aaaaactata
     4681 gaaataaata aaaaaagtca aattgacctt ttaatattag ctgacccatg tgaagaaatg
     4741 attgataaat atctcaataa aggaactatg tacgcattgt atgataataa agaacttact
     4801 tgtatagcag ttgtaaatga aatttccaaa gaaatatgtg aattaaaaaa cattgctaca
     4861 tatgagcatt ttcaaaatat gggttatgcc tcaaagatga tttatcatct tttagatgtt
     4921 tatagtaaaa aatattcatc aatggttgtt ggtacatctg aaagtggagt tcctttttat
     4981 gagaagtttg gatttgttta ttcacataaa attaaaaact tttttgtaga taattatcca
     5041 gaaccaatct ttgaaggaga attacaatgt gttgacatgt tgtatctatc atataacttt
     5101 tagataggat aatattttta ggttaatata attaattaat tcatataatt atcggaatta
     5161 taatttataa attatgtata ataagagtat aatttattta gaagctgtta tattgtatta
     5221 gattcaaata agatatataa taacttgttt attttgaatt ttggaggatt aattatggat
     5281 tcaaataata atactataaa atcaactgtt aaaaagggta tttcttttgg ttcttgttta
     5341 gcaatgatta tttcttatac tgcatggaaa tctattccat gggctatttt tcatggctta
     5401 atgagttgga tatatgtact ttattattgg gttaagtatg catagattaa attaataaat
     5461 aagtatgtaa tattgtaaag tttaagaaac aaaatgtaag ggagtgtctc gaagtgaact
     5521 tttagtttat aaggcactct tttttgtatt aaataaaata tattttcatt acttaaacaa
     5581 tgaaaaagat gagtatctct attttaatac atacccttat attcattcat ttatcaacaa
     5641 tagttttaaa aagaaagcta tctaaaatct attgtaatct aagtgcttct ctttaaagtc
     5701 ttaactttag taatgatata taagtttata aggttcttat ttcaataatg caaattttac
     5761 ttagaagttc agactttggt atgaagaaat gggtaataat aaaaaagagg tgttgatatg
     5821 aaagaaaaat tagaagaaaa atctaagatt attaaaacat caaaagagta taaacgaact
     5881 ataattgaag aaaaggacag agaatggacc caaaaattaa atgacatact tagtagaggt
     5941 gatttttcta atgaaaaatt agataaaatc aaggatttaa ttccaaaaga aatattgact
     6001 agtgaaaatg ttggagaagt tgtaactgaa gatgggtatg ctaagcctga gtatgatgag
     6061 gtatttaaat cattgtttac tttaaataat gattacgatt tacttgcaaa ttttataaat
     6121 gatatcctca aagatgctcc atatgctaat aggaatatca aacagttcac tcaaataaaa
     6181 agaataatta aggttgaaac cgacccaaca attaattaca ttggtgagaa aagacctaga
     6241 cttgatattt tggctgaaga tgaagaacgt aaccatataa atattgagat gcaaagagct
     6301 cttgaagagg attatttgga aagagctgaa tattatctta gtcgtgtaca tggtagaaag
     6361 ttagaagaag gtaaagaata taaagaaatt ggaaaaactg ttggaataca tatactaaat
     6421 catgtaaaat ataatcacat agaagattat gtaaattgcc tgagattaac aatggacggg
     6481 catccagata ttttttctag taaaactgca ttatatttta tagaacttcc aaaaattcgt
     6541 aaatccagtt gtatagcaaa cagagttcta atatggggta aacttattga taatccttct
     6601 catatagata ttagaatact atctaaaacg gattatgtta ttaaaagagc acttgataga
     6661 ttaaaagaat taggtagtaa tgaggactat ttattaaatt taaagagagg tgcgtatatt
     6721 atgaataaaa gtagaaattt taaagaagaa atttttcaag aaggtattga aaaaggtatc
     6781 gaaaaaggta tcgaaaaagg tattgcaaaa gggaaaagag aagagaaatt taatatcatc
     6841 ataaaattaa aaaataaagg atacaatttg agtgaaatat gcgatattat agatgatttg
     6901 aataaatcag aggttgaaaa agtctataat caaaactaat actatgattg agatggcact
     6961 agataaatac aaagcttcct cttttaaatt taaattaata taaaactttg ttatttaaat
     7021 atggtagata taaagagata tataaataat aggtacaaag aggtgtataa ataaaggaga
     7081 taattcaaaa taaaagtttg aaccatctcc ttcttataga aaaacaaagg ggttgattta
     7141 tatatgaaat tttatactat acagacttta gaattttgga ataacaataa aaacaataaa
     7201 tatctatcaa atgattattc ttttatatta gaagactttg atattccata caaatggatg
     7261 tatagtcaaa tgacaaatag aatatatgaa tttgatgata gtatgatatg ggtttggacg
     7321 aagagacctg atttaagatg tagtggttat ttagaaaaag gaaaaaaagg tgttttactt
     7381 gaaatagaaa taagtgaaga caatgtgtta ttatcagaat ttgatttatg gcatttacct
     7441 ttaatggata ttactgtaga gctttatgaa gatgaacaaa ttgaaaagaa ggtaagttgg
     7501 gaaagaatat ttgacttaga actgtgttca aaattaaatg aagttaatat agaagatttg
     7561 acattgcaag gagtgacatc taaagtgcct ctatctaatg taaaattaat aaaagaattt
     7621 gttgcaaaat aatattttta ttgaaattta ttcaaaaaag ttatatattt ataacaagag
     7681 gtgttataaa tacataactt tttaaggggg attttatatg tctaaacaac aaactggtat
     7741 taaatcaaca cttatttcag aaatattggg aatttcttat tgtattggag ctacattagt
     7801 aaataagtat ttttttaaag gaagtagtat tgaatatctt cctataatta tttgggtatt
     7861 agctatggga gctcagtggg tctataataa aaagtatgat gatttaattg atgaggcatc
     7921 aaaatgtata ctatcaagag ttaatgatat tgcaataaaa gtattgtttt tttctgtagc
     7981 tatagtatct atatttcttg taactttgga cataaatgtg tcaaatttaa atataggaat
     8041 gtctttatta gtcattttgt ttattcaatc cttgttgaag ttaattctat ttatatattt
     8101 tgacagaaag gggatataca attaggtgtc agtattacta aagacaaaaa ttaaatccta
     8161 tagagaaaag aaccttatga cacaaggtga acttgcaaag tcagtaggag taagacgtga
     8221 aactattgta catttagaaa atggtcgcta caatccttct ttaaaactgg caatggatat
     8281 tgctaaggta tttgatacaa ctgtagaaga gttgtttgaa tttattgaag aaaataatat
     8341 ttaaatttca tgtattactt atgcattaga gaatgaatta attataggta aaaaaccaag
     8401 cttatagatt agagaataaa tgacttatag atgaaaaacc aagctaatgg attaaagagt
     8461 gaatgattta tagattaaga agtaagctta tagattagag aataaatgac ttatagatga
     8521 aaaaccaagc taatggatta aagaatgaat gatttataga tgaaaaagaa agcttataga
     8581 ttagagaata aatgacttat agatgaaaaa ccaagctcat agattaaaga atgaatgatt
     8641 tatagatgaa aaagaaagct tatagattag agaatgaatt aattataggt aaaaaacaag
     8701 ctaatagatt aaaaaatgaa tgatttatag attaagaagt aagcttatag attagagaat
     8761 aaatgactta tagattaaga agtaagctta tagattagag aataaatgac ttataaataa
     8821 aaaccaagct tatagattag agaataaatg acttataaat aaaaaccaag cttatagatt
     8881 agagaatgaa ttaattatag gtaaaaacca agcttataga ttaaaaaatg aatgatttat
     8941 agatgaagaa ctaaacttat agattaaaaa ataaatgact tatttataga tgaaaaacca
     9001 aacttataga ttaaaaaata aatgatttat agatgaagaa ctaaacttat agattaaaaa
     9061 ataaatgact tatagatgaa aaatcaagct catagattaa agaataaata acttattaga
     9121 tgaaaaacca agcttataga taagaagtcc atgcttataa gccagaaaat gaatagttta
     9181 atagattaaa aaatacatat ttgtgaatta tagaatgaat aactccataa actagaaaat
     9241 ttataataat atctatatga aaattagaat tattttatca caaaaaaatt aagttaaata
     9301 aatatgaaat tacttccaaa tatacttcca aaaacatgta atcgcatata taatataatt
     9361 ataaaaataa taaatatttt tatagtagta gttaattatt aataaggagg ggtcaaaatg
     9421 cctagcatga ttatggaagt tgtaggagta ctatttatag ctattggatt aatcttgaca
     9481 ttcattgaaa taaaaggaaa tttcccttct ttttatggtt ttggtcaaaa ttaaaatgct
     9541 gtaggtatta tagcagcagg aattgcttta attttcttta gaaatggcat agatacatag
     9601 attctatagc tacttatg
//
LOCUS       DAEPKC010000122         9430 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.123, whole genome shotgun sequence.
ACCESSION   DAEPKC010000122 DAEPKC010000000
VERSION     DAEPKC010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9430)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9430)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9430
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.123"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            50..1492
                     /locus_tag="KR294_003301"
     CDS             50..1492
                     /locus_tag="KR294_003301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HBH0241355.1"
                     /translation="MRTIRRVLALGLTLAIFLINVPNVDALTSDTIKGNNIYETAGLI
                     ADKKSYDTAIMVNMDNSIADGLSASGLAGAVDAPILLAQKNKIPNETKQRLKNVKKIY
                     IIGKELSISKSVETELKNTGAQVTRLGGDDRIKTSYSVAKEVNGIKKVDEVILTNAYK
                     GEADTISAAPVSVRDIAPIVLTDGKSVPFSTSNVKTYAVGGSISMSTSLVNKTNAKRL
                     GGSDRYDTNKKVIKEFYPDASEFYLSDGYDLVNALTGSTIAKENPIVLVSESSDKSIL
                     AGADKITRLGSISDSVYNKCVSAAQNNGDSSTKGESPMKNETSILGQPTASLEACLKW
                     AKSKKANDLFIELIPILYDTAVQEGVNPVLAVAQSAKETGFCNFGGVLDASFKNPCGL
                     KTSVGGSDTDKNAHSRFDTWEEGILAQIQHLCLYAGQDGYPLSNPVDPRHEKSLFGKA
                     KTVESLSNNWAGGQYGQDLVRMMGEIEATK"
     gene            1534..1887
                     /locus_tag="KR294_003302"
     CDS             1534..1887
                     /locus_tag="KR294_003302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241356.1"
                     /translation="MKKSNIFSIIFPTVIMVLMFLTFATDIFNIPDIQSKSIFVVGMV
                     LIFPISFLIQGIICVLNKTNWILSLIVSLVTYIVLMYIFLNDSAYIYVLLYTAFYMIG
                     HITAKLYYKIKTFKN"
     gene            2078..2899
                     /locus_tag="KR294_003303"
     CDS             2078..2899
                     /locus_tag="KR294_003303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase HisJ family protein"
                     /protein_id="HBH0241357.1"
                     /translation="MNLIDNHIHTNFSSDGKDSMEDTIKKAISIGVRYLTFTDHLEHD
                     EDRGFCINYNDYVPVFNKFKEKYKKDIELLLGVEVGYRKHLKNEIEEIINSNPFDFVL
                     CSTHTIDNVPVPSKEYFKGLSKEDAYYKYFNSILETNREFGDYNIYGHLDYISRYGIY
                     SDNRVIYNDFKDVIDEVLKSIINNGSGIELNTSGYRYGLNAIHPNEDILKRYKELGGF
                     IVTVGSDSHRVEDICKDFDVAYDMLKYLDFKYVSLFKERETYFVNIEKVKSNNIA"
     gene            3157..5040
                     /locus_tag="KR294_003304"
     CDS             3157..5040
                     /locus_tag="KR294_003304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HBH0241358.1"
                     /translation="MSNKNKENITLSNQIKGTIQNSLTKEAILHIPMSNYAYGYDRET
                     LHIRLRTKKNEAKRVILRIGDQYVWDKGGAGGGNLNASGVGWSGGTNIVMSKEVETEL
                     FDYWIAKCKPLNKRSRYGFIIEGQEEKLLFTEKRIIELGNENDEKELCEIGNFFGYPY
                     LNYIDIPKVPNWVKDTVWYQIFPDRFANGDPSINPEGVDKWGAIPTRDNFTGGDLQGV
                     IEHLDYLSDLGINGIYFCPITIGKTNHRYDTVDYMEVDPTLGDKETLKKLIEEAHKRN
                     IKIMLDAVFNHIGYYSKQWQDVVQNKENSRYKNWFYIKDMSKIDTPIEQIDEKNIPYE
                     TFGCEKYMPKLNTENSEVIKYLLDVGKYWIQEFDIDAWRLDVSNEVDHVFWRKFREEV
                     KKVKPDIYILGEIWHGSLPWLMGDQFDSVMNYLMSEAMKKFFCTDEINAEEFKYMIND
                     VMVSYPIQVSEVIFNLLGSHDTTRILTYANGNIDRFKLAYMFMFVQTGCPCIYYGDEI
                     GMEGELSSISEGQRKCMEWNEEKWNKDIFDFMKKIIRLRKENKELRSISNEWVLADKE
                     NGTIILKKESISIIINNSSKNIILTLPDYLANKKVKDLYEEEIVDLKEELMLEKYKFI
                     ILK"
     gene            5265..5945
                     /gene="pgmB"
                     /locus_tag="KR294_003305"
     CDS             5265..5945
                     /gene="pgmB"
                     /locus_tag="KR294_003305"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HBH0241359.1"
                     /translation="MIEAFIFDLDGVITDTAYYHYMAWRKLAHKVGIDIDTKFNESLK
                     GISRMESLDRILEFGNKKYSFSEEEKVRMAEEKNNYYVSLIDEITSNDILPGIESLLI
                     DVKSNNIKIGLSSASKNAINVLNHLGISDKFDFIADAGKCKNNKPHPEIFLMSAKGLN
                     VNPQNCIGIEDASAGIDAINSANMFSVGVGNYENLKKANLVVDSTNQLKFEYIQEKYN
                     EYIVRRII"
     gene            5942..8227
                     /locus_tag="KR294_003306"
     CDS             5942..8227
                     /locus_tag="KR294_003306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HBH0241360.1"
                     /translation="MKCLFSNVDEWKIIQDKIEIKENRLAESIMSIGNGYMGMRGNYE
                     ENYSGDTHKGSYIAGVWFPDKTRVGWWKNGYPEYFGKIPNSVNYIGVRIFIDDVELDL
                     AKCKVEDFYRELDMKNGILNRRFIVNINDKKFEVRVARFLSISVKELAVIKYSIKSLN
                     SNTKIKFVPYLDSNIKNEDSNYEEKFWNGISSSSLEYKGSILSRTKENAFNTPVFTVG
                     SMMYIKTNGDVEAVSHESDYNYCENSITMDVLKNEVASIEKYVSITSTRDYKESELLR
                     KCEDILNRELSKSYDDILNEHTKLWNKRWESADVKINGDKSSQQGIRYNLFQLFSTYY
                     GEDSRLNIGPKGFTGEKYGGATYWDTEAFCVPVYLGVADKEVTRNLLEYRYNQLEQAK
                     DNAKKLGLKGALYPMVTFDGVECHNEWEITFEEIHRNGSIVYAIYNYTNYTGDYKYIK
                     EKGIDVIIEIARFWASRVHLSTKKDLYMIHGVTGPNEYENNINNNWYTNYIAKWCLDY
                     AVENILRLEKECNECIDRNNVTREEVEFWKIISNKMYLPYDEELQIIIQNDNFLDKEF
                     VEVKDLPKENFPLNQNWSWDKILRSCFIKQADVLQGIYYFGNRFTKEEKKRNFDFYEK
                     YTVHESSLSSSIYSIIASEIDNLEKAYELYSRTARLDLDNYNNDTNDGLHITSMSGSW
                     LSIVHGFAGMRTWNETLSFDPKLPKEWKNYSFNINYRDNIINVDVCSDLIKIENLKGR
                     PIKIIVYGKKYILEKCIKIDK"
     gene            8452..9345
                     /locus_tag="KR294_003307"
     CDS             8452..9345
                     /locus_tag="KR294_003307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HBH0241361.1"
                     /translation="MKNKKFIVIILIISILIGVLVKEYSSREIKKDDINVSKYIKYAD
                     LASKNNAQVNWKYVASIVAVLNKNNLKNVKDSQIQEVSDLFVKNFSKNNKINKLSDIL
                     DELEFSNRQKRLVDNYIDNLKDYGIKPERLKSDTKYMKFIDEIKTEAIQNYKDYKILP
                     SITIAQAIIESSWGKSTLAKQYSNLFGIKADAYWKGKSVTLETKEHLDTIIDDKFRIY
                     DDKNESIKDHAKFLATNKRYKNNGVFDAKTYIYQAKALEKAGYSTAKDENGNSIYAAR
                     LIELIQQYNLQLIDSEIQSEM"
BASE COUNT         3829 a          878 c         1698 g         3025 t
ORIGIN      
        1 atgttatagt catttttgaa ttaaacttga tatatcaagg gggaagaata tgagaacaat
       61 tagaagagtt ttagcattag gtttaacatt agctatattt ctaataaatg tacctaatgt
      121 agatgcatta acatcagata caattaaagg taacaatata tatgagacgg ctggattaat
      181 agcagataaa aagagttatg atacagcaat tatggtaaat atggataatt ctatagcaga
      241 tggtctttca gcaagtggtc ttgcaggtgc tgttgatgct ccaattttgc ttgcacaaaa
      301 aaataagata ccaaatgaaa caaaacaaag attaaaaaat gttaaaaaga tatacataat
      361 aggtaaagaa ttatcaataa gtaagtcagt agaaactgaa ctaaaaaaca caggggcaca
      421 ggtaactaga ttgggtggag atgacagaat aaagactagt tatagtgttg ctaaagaggt
      481 aaatggtatc aaaaaagttg atgaagtgat attaactaat gcatataaag gagaagcaga
      541 tacaataagt gctgcacctg tatcagtaag agatatagct cctatagtac ttacagatgg
      601 aaagagtgta cctttttcaa caagcaatgt aaaaacatat gcagtaggtg ggagtatatc
      661 aatgagcact agtttagtta ataaaactaa tgctaaaaga cttggtggtt cagatagata
      721 tgatacaaat aagaaagtta taaaagagtt ttatccagat gcatcagaat tttatttgag
      781 tgatggatat gatttagtaa atgcacttac aggttctaca attgctaagg aaaatccaat
      841 tgtattggtg tcagaaagta gtgataagtc tatattagca ggagcagata agattactag
      901 attaggttca ataagtgaca gtgtgtataa taagtgtgtt tctgctgcac aaaataatgg
      961 cgattcgtct acaaaaggtg agtcacctat gaaaaatgag acaagcatat taggtcagcc
     1021 aacagctagt ttagaagcgt gcttaaaatg ggcaaaatct aaaaaagcta atgatttatt
     1081 tatagagtta ataccaatat tatatgatac tgctgttcag gaaggtgtta atcctgtttt
     1141 ggcagtagct caatctgcaa aagaaactgg tttttgtaat tttggtggag tattagatgc
     1201 atcatttaag aatccttgtg gacttaaaac ttctgtagga ggttctgata ctgataagaa
     1261 tgcccattca agatttgata cttgggaaga aggaatatta gctcaaattc aacatttatg
     1321 cttatatgca ggacaagatg gttacccact ttcaaatcca gtagacccta gacatgaaaa
     1381 atctttattt ggtaaggcta aaacagttga aagtttatct aataattggg ctggaggtca
     1441 atatggacaa gatttagtaa gaatgatggg agaaattgag gcaacaaaat aattgaagat
     1501 tatcaaatat ccaataaata aggattgatt attatgaaaa agagtaatat ttttagtatc
     1561 atatttccta cagtcataat ggtgctaatg tttttaactt ttgctacaga tatatttaat
     1621 attccagata ttcaatctaa aagtattttt gttgtgggaa tggttttgat ttttccaatt
     1681 tcttttttga tacaagggat aatttgtgta ttaaataaga ctaattggat tttatctctt
     1741 attgtgtctt tagtaactta tatagtatta atgtatatat ttttaaatga ttctgcatat
     1801 atatatgttt tactttatac agctttttat atgattggac atataacagc taaactctat
     1861 tacaaaatta agacttttaa aaattaaatt gaagtatata aaagtaacat taggagaagt
     1921 atccttaatg attttctaaa atcagaaata ggtgcttctc ttttttgtaa aaataaaagt
     1981 atgtaaataa aatttaacca ttataatttt cttttaacaa atgtatacaa taaacttgtt
     2041 gtataattaa gatagataaa ataaagggag ggataatatg aatttaatag ataatcatat
     2101 tcatactaat ttttcaagtg atggaaagga ttccatggaa gatacaataa aaaaagctat
     2161 aagtattggt gttagatatt tgacttttac agaccattta gaacatgatg aagatagagg
     2221 attttgcata aattataatg actatgttcc agtatttaat aagtttaaag aaaaatataa
     2281 aaaggacata gagttattac taggtgttga agtgggttac agaaaacatc taaaaaatga
     2341 aatagaagaa ataataaatt ctaatccttt tgattttgta ttgtgctcaa ctcatacaat
     2401 tgacaatgta cctgttccat caaaggagta ttttaaaggt cttagcaaag aagatgcgta
     2461 ttataaatat tttaatagca tacttgaaac taatcgtgaa tttggagatt acaatatata
     2521 tggtcatttg gattatatat ctaggtatgg aatatattca gataatagag ttatatacaa
     2581 tgactttaaa gatgttattg atgaggtctt aaagtcaata atcaataatg ggagtggtat
     2641 agagctaaat acttctggtt atagatatgg attaaatgct atacatccaa atgaagatat
     2701 tctaaaaaga tataaagaac ttggaggatt tatagttact gtaggttctg attctcatag
     2761 ggtagaagat atatgtaaag attttgatgt ggcctatgat atgcttaagt atcttgactt
     2821 taaatatgta tctttattta aagaaagaga aacttatttt gtaaatatag aaaaagttaa
     2881 atctaacaat atagcttaga gtgtgttttg aagtaaatta atggatagtt aaaaagttaa
     2941 tagttataat attgtatcct ctagaaaaat actagaggtt tttattttgc taaaataact
     3001 aaatagaatt aaatttaaat agtatagttt attttaaatt gaatagttta ttgttgatat
     3061 attttactat tatatatttt tattgtgata taatagtaaa atatattaac ctatctttag
     3121 attatataaa ttattataaa ggagggaaat tttaaaatgt ctaataaaaa taaagaaaat
     3181 ataactttaa gtaatcaaat caaaggaaca attcaaaata gtttaacaaa agaagctata
     3241 ttacatatac caatgagcaa ttatgcctat ggttatgata gagaaacact acatataaga
     3301 cttagaacta aaaaaaatga agcgaaaaga gtaattttac gaataggaga ccaatatgtg
     3361 tgggataaag gaggtgcagg aggaggaaat ttaaatgcat ctggagttgg ttggtctggt
     3421 ggaacaaata tagtaatgag taaagaagta gaaactgaat tatttgacta ttggatagct
     3481 aagtgtaagc ctttaaataa acgctcacga tatggcttta taatagaagg tcaagaggaa
     3541 aaacttttat ttacagaaaa aagaataata gagttgggaa atgaaaatga tgaaaaggaa
     3601 ttatgtgaaa taggtaattt ttttggatat ccatatttaa attatataga tatacctaaa
     3661 gtgccaaatt gggtgaaaga tactgtttgg tatcagatat ttccagatag atttgcaaat
     3721 ggtgacccgt ctataaaccc agaaggagta gataaatggg gagctattcc aaccagagat
     3781 aattttacag gtggagattt acaaggtgtg atagaacact tagattattt gagtgatttg
     3841 ggaataaacg gaatttactt ttgccctatt acaattggaa aaaccaatca tagatatgat
     3901 acggtagatt atatggaggt agaccctaca ttaggagata aagagacttt aaaaaaacta
     3961 atagaagaag cgcataagag aaatataaaa ataatgttgg atgctgtttt taatcatata
     4021 ggatattatt ctaaacagtg gcaagatgta gttcaaaata aggaaaattc tcgatataaa
     4081 aactggtttt atataaaaga tatgagtaaa attgatactc caatagaaca aatagatgaa
     4141 aaaaatatac cttatgaaac ctttgggtgt gaaaaatata tgcctaaact taatacagaa
     4201 aattcagaag taataaaata tttattggat gtaggcaagt actggataca ggaatttgat
     4261 atagatgcgt ggagattaga tgtttcaaat gaagtagacc atgttttttg gagaaagttt
     4321 agagaagaag tcaaaaaagt aaaaccagac atttatatat tgggagaaat ttggcatggt
     4381 agtttaccat ggctaatggg tgaccaattt gattcagtta tgaattactt gatgtcagaa
     4441 gccatgaaaa aattcttttg tacagatgag ataaacgccg aagaatttaa gtatatgata
     4501 aatgatgtaa tggtaagtta tccaatacaa gttagtgaag ttatttttaa tttacttgga
     4561 agtcacgata ctacaagaat attgacttat gctaatggaa atattgatag atttaaactt
     4621 gcatatatgt ttatgtttgt acaaacagga tgtccttgta tatactatgg tgatgaaatc
     4681 ggaatggaag gagaattaag ttcaatatct gaaggtcaaa gaaaatgtat ggaatggaat
     4741 gaagaaaaat ggaataagga tatatttgat tttatgaaga agattattag acttcgtaaa
     4801 gaaaataaag aacttaggtc tatatcaaat gaatgggtgt tagcagataa ggaaaatgga
     4861 acgattatat tgaaaaaaga atctatttct ataataataa ataattcatc taaaaatata
     4921 attttgacgt taccagatta tttagcaaat aaaaaagtaa aagatttata tgaagaagaa
     4981 atagttgatt taaaagaaga actaatgtta gagaaataca agttcattat tttaaaataa
     5041 tacaaaaaag tatttatttt agatttcatg ttaaattatt atacagttta aataagtctt
     5101 tataaacgat aaaaaaatat ggtctacaag tgagtgaatt gaaagtagat tttaaattaa
     5161 agactgagtt agagtagata attttataaa taatatctta aatacaagat agaaaataaa
     5221 ttgattatta gtctaaaaat ttcttgtaga aagaggaaat aagaatgatt gaagcattta
     5281 tatttgattt agatggtgta attacagata ctgcatatta tcactatatg gcttggagaa
     5341 aactagccca taaagttggg atagatatag acacaaaatt taatgaatct ttaaaaggca
     5401 taagtagaat ggagtcattg gacaggatat tagaatttgg aaataagaaa tattcatttt
     5461 cagaagaaga aaaagtgaga atggctgaag aaaaaaataa ttactatgta tcattgatag
     5521 atgagataac ttcaaatgat attttgccag gtatagaaag cttgttaatt gatgtaaaat
     5581 ctaataatat aaagataggt ctatcttctg caagtaagaa tgcaataaat gtattaaatc
     5641 atttgggtat aagtgacaaa tttgatttta tagctgatgc aggaaaatgt aaaaacaata
     5701 aaccacatcc agagatattt cttatgtcag cgaaagggct taatgtaaat ccacaaaatt
     5761 gtatagggat agaggatgca agtgcaggta tagacgctat aaactcagct aatatgtttt
     5821 ctgttggtgt tggaaattat gaaaacttaa aaaaagcaaa tttagttgta gattcaacaa
     5881 atcaattaaa gtttgaatat atacaagaaa agtataatga gtatatagtt aggagaatta
     5941 tatgaaatgt ttatttagta atgtagatga gtggaagatt atacaagata agattgaaat
     6001 caaagaaaat agattagcag agtccataat gagtataggc aatggatata tgggtatgag
     6061 aggaaactat gaggaaaatt atagtggaga tacacacaag gggtcttata tagctggagt
     6121 atggtttcca gataaaactc gtgttggttg gtggaaaaat gggtatccag aatactttgg
     6181 taaaattcct aattcagtca actatatagg tgtaagaatt ttcatagatg atgtagaatt
     6241 agatttagca aaatgtaaag tagaagattt ttatagagaa ttagatatga aaaatggtat
     6301 tttaaatcgt aggtttattg taaatataaa tgataaaaaa tttgaagtta gggttgctag
     6361 gtttttaagt atatctgtta aggaacttgc agtaattaaa tacagtataa aatcattaaa
     6421 ttctaatact aaaataaaat ttgtaccata tttagattca aatataaaaa atgaagattc
     6481 aaactatgag gaaaagtttt ggaatggaat ttcttcaagt tctttagaat ataaaggtag
     6541 tattctttct cgaacaaagg agaatgcatt taatacacca gtattcactg tgggttcaat
     6601 gatgtatatt aagacaaatg gtgatgtaga agctgtatct catgagagtg attataatta
     6661 ctgtgaaaat tcgataacaa tggatgtttt aaaaaatgag gttgcaagta tagaaaaata
     6721 tgtatctata acttcaacta gagattataa ggaaagtgag ctattaagaa aatgtgaaga
     6781 cattttaaat agagaactat ctaaaagtta tgatgatata ttaaatgaac atacaaagtt
     6841 atggaataaa agatgggaaa gtgcagatgt aaaaataaat ggagataaaa gtagccaaca
     6901 aggtataaga tataatttat tccaactatt ttcaacatat tatggagaag attcgcgatt
     6961 aaatataggt ccaaaaggat ttactggtga aaagtatgga ggagctactt attgggatac
     7021 agaagcgttt tgtgttccag tatatctagg tgtagcagat aaggaggtaa ctagaaatct
     7081 tttagaatat aggtacaatc agttagaaca ggcaaaggat aatgcaaaaa aactagggct
     7141 taaaggtgct ttatatccaa tggtaacatt tgatggagta gaatgtcata atgaatggga
     7201 gataacattt gaggaaatcc accgaaatgg aagtatagta tatgcaatat ataactatac
     7261 aaattataca ggtgactata aatatataaa agaaaaagga atagatgtaa taatagaaat
     7321 agctagattt tgggcaagta gagttcattt gtctacaaaa aaagatttgt atatgataca
     7381 tggagtaaca ggtccaaacg agtatgaaaa caatatcaat aataattggt atactaatta
     7441 tatagctaaa tggtgtttag attatgctgt agaaaatatc ttacgattag agaaagagtg
     7501 taatgaatgt attgacagaa ataatgtgac tagggaagaa gttgagtttt ggaaaataat
     7561 atcaaataaa atgtatctgc cgtatgatga ggaactacaa ataataattc aaaatgataa
     7621 ttttttagat aaagaatttg tagaagtaaa ggatttacca aaagaaaatt ttcctcttaa
     7681 tcaaaattgg tcttgggata agattcttag gtcgtgtttt ataaaacaag cagatgtatt
     7741 acagggaatt tactattttg gaaatagatt tactaaagaa gaaaaaaaga gaaattttga
     7801 cttctatgaa aaatatactg tacatgaatc ttctttatct tctagtattt attctattat
     7861 tgcctcagaa atagataacc tagaaaaggc ttatgaatta tattcaagaa cagctaggct
     7921 tgatttagat aattacaata atgatacaaa tgatggactg cacataactt caatgtctgg
     7981 ttcatggctt tccattgtac atggatttgc aggcatgaga acatggaatg aaactctatc
     8041 ttttgaccct aagttgccaa aagagtggaa aaattattct ttcaatataa attatagaga
     8101 taatattatt aatgtagatg tatgtagtga tttaattaaa atagaaaatt taaaaggtag
     8161 accaataaaa attattgtat atgggaaaaa atatatatta gaaaaatgta taaaaattga
     8221 taaatagatt taataatatt tttattatat aaatagttaa aataagctat ctaattattt
     8281 atttatttta actattttgt gtgatagaaa actatatatt ataacaatag tagtgctttt
     8341 aattaaatat atttcataaa tcttcataaa atcttcaaaa tttcgtaaag aatatgtcac
     8401 aaaagtaagg tatattatat tcagcagata gtataaggga ggacaatatt tatgaagaat
     8461 aaaaaattca ttgttataat actgataata tcaattttaa taggtgtatt agtgaaggaa
     8521 tattcatcta gagagataaa aaaggatgat ataaatgtca gtaagtatat aaaatatgct
     8581 gatttagcaa gtaaaaataa tgcacaagtt aactggaagt atgtagcttc cattgttgct
     8641 gtgttaaata aaaataactt aaaaaacgtt aaggattcac agatacaaga agtatcagat
     8701 ttatttgtta agaatttttc taaaaataat aaaataaata agttaagtga tattttggat
     8761 gagttagaat ttagtaatag acaaaaaaga ttggttgata attatataga caatcttaag
     8821 gattatggta taaaaccaga aagattgaag tctgatacaa aatatatgaa gtttattgat
     8881 gaaattaaaa cagaagcaat acaaaattat aaggattata aaatacttcc atctataact
     8941 attgcacaag ctataataga atctagctgg ggcaagtcaa ctttggcaaa acaatatagc
     9001 aatctatttg gtataaaggc tgacgcttat tggaaaggta agtcagtgac tttagaaacg
     9061 aaagaacatt tagatacaat tatagatgat aaatttagaa tatatgatga taaaaatgaa
     9121 tctataaaag accatgcaaa atttttagcc acaaataaaa ggtataaaaa caatggtgta
     9181 tttgatgcaa aaacgtatat atatcaagct aaagcattag aaaaggcagg ttatagtact
     9241 gcgaaggatg aaaatggcaa tagtatatat gcagctcgtc taatagaatt aattcaacag
     9301 tataatcttc aattaataga cagtgaaatt caaagtgaaa tgtaactttg attaaatttt
     9361 tattgataag gctatgattt ttaaaatcat agccttattt tgacatgctt ttacttgtaa
     9421 ttattaaatc
//
LOCUS       DAEPKC010000123         9407 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.124, whole genome shotgun sequence.
ACCESSION   DAEPKC010000123 DAEPKC010000000
VERSION     DAEPKC010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9407)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9407)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9407
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.124"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            491..1696
                     /locus_tag="KR294_003308"
     CDS             491..1696
                     /locus_tag="KR294_003308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HBH0241362.1"
                     /translation="MSKKVLIMSASTGGGHNRAALAIKEELTSKTLDGEPIECEIIDS
                     LKLVNNTMDKIISRGYEKSAIYTPKAYGSVYRLSETNLLSKNEFKDNLLITFMAKKFK
                     KLIRSEKPDLIIGTHPFPMIALSTLKKNFNLHNNESNAYTEHFYKHYTNTINVPPLIS
                     VLTDYTTHSTWIQNEIDYYIVGHEYVKELLVFDGVEPSKIRTFGIPVEKSFLSHRDKD
                     IVLSELNLSPDKLTVLLMGGSFGAGNIKETLDELLDTDRDFQILVITGKNESLKEKIE
                     KKLMSRYHDKNVCVLGYTDKMNDILASIDVLVSKPGGLTTTEALLKDVPMIVPYYIPG
                     QEEENLDFLSNCGAALRTTKKYNLSILLKVLIDDPSRLEMLKRNIKSIRKSNSAQNIA
                     NLILNIISG"
     gene            complement(1767..1988)
                     /locus_tag="KR294_003309"
     CDS             complement(1767..1988)
                     /locus_tag="KR294_003309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241363.1"
                     /translation="MKPIMNLEEHNAMKEKRVKKMKSKDKPKYDDFEDISFSNKKKTK
                     KNVRNKNAEFRNNYKNYQYDYEEDFYEPI"
     gene            complement(2129..2728)
                     /gene="recR"
                     /locus_tag="KR294_003310"
     CDS             complement(2129..2728)
                     /gene="recR"
                     /locus_tag="KR294_003310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012634696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HBH0241364.1"
                     /translation="MQVYTGPITRLIEEFSKLPGVGRKTAQRLAFHIINMNTNDVEAL
                     SKAIIDAKREIRYCSICCNITDTDPCSMCSNKSRDSSVICVVEDPRDVAAMERTREFK
                     GQYHVLNGVISPMDGIGPDMLKIKELIQRLGNQEVKEIIMATNPTIEGEATAMYIARL
                     VKPMGIKVTRIAHGLPVGGDLEYADEVTISKALEGRREI"
     gene            complement(2741..3091)
                     /locus_tag="KR294_003311"
     CDS             complement(2741..3091)
                     /locus_tag="KR294_003311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HBH0241365.1"
                     /translation="MAKKGFGGGMMPGGGNMNNLLKQAQKMQENMQKAQQELESKEVE
                     ASVGGGAVTVKVNGKKEVIDITIKPEVVDPDDIEMLQDLVLSAVNQALRNIDDIQASQ
                     MSKVTGGMNIPGLF"
     gene            complement(3150..4787)
                     /gene="dnaX"
                     /locus_tag="KR294_003312"
     CDS             complement(3150..4787)
                     /gene="dnaX"
                     /locus_tag="KR294_003312"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HBH0241366.1"
                     /translation="MHKALYRAYRPQKFEDVIGQDHIIKTLKNQIYSDNIGHAYLFCG
                     TRGTGKTSTAKIFSRAVNCLNKINEEPCNECEICESVLKDNTMDVVEIDAASNNSVDD
                     IRELRESVKYSPANAKYKVYIIDEVHMLSQGAFNALLKTLEEPPSYVIFILATTEPHK
                     IPATILSRCQRYDFKRVTVKDMTLRMKKICEDEGIDIDDKALNLIARNSQGALRDALS
                     ILDQCMSFGESKIDYKDVVELMGSVNIEQLFELSQCIVEQDTKKSLEILNEFVLWGKD
                     IRNLINDLIDHFRNLMVCKVSSELDEIISLPEETIEQLKIQSKNIDINDLIRILNILS
                     ITQDDIKSSSNPRVLVEITIMKIAQPMFDESKEALIKRVENLEKMIELGNFKSEKIGN
                     NKEKEYEVDREIDVKQENVVYEDVKNEDVILIESSWKNILKQIKKDKKMPIYALLSEV
                     KSFNVYSNMLYVIFDDKFDFAKTRLSSQDTINYLEKTIRDVLNRSFNVKIVLTSEVKD
                     INLEVKEKKDIGEEILKNIVSEEILEIKDSIDENESK"
     gene            complement(4864..5128)
                     /gene="ffs"
                     /locus_tag="KR294_003313"
     ncRNA           complement(4864..5128)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="KR294_003313"
                     /product="signal recognition particle sRNA large type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01854"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF01854"
     gene            complement(5166..5257)
                     /locus_tag="KR294_003314"
     tRNA            complement(5166..5257)
                     /locus_tag="KR294_003314"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5221..5223),aa:Ser,seq:gga)
     gene            complement(5258..5713)
                     /locus_tag="KR294_003315"
     CDS             complement(5258..5713)
                     /locus_tag="KR294_003315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HBH0241367.1"
                     /translation="MESSFYMKEALKEAYKAYNKKETPIGAIIVKDNQIIARAHNLTE
                     TLKDSTAHAEILAIKQASEKLGGWRLTDCDLYVTMEPCIMCSGAIVNSRIKKLIIGTR
                     HVKNSYIEKQHEFKLDYFNNNNVKVAFDVLQEECSIILQEFFKALRKRD"
     gene            complement(6034..7305)
                     /gene="serS"
                     /locus_tag="KR294_003316"
     CDS             complement(6034..7305)
                     /gene="serS"
                     /locus_tag="KR294_003316"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HBH0241368.1"
                     /translation="MLDIKRIRENLDDIKKAMERRGEREFDLDAVVELDNKRREILQE
                     VEVMKNELNVNSKKIPQLIKEGKDVTEEKARLKELSDKIKGIDEKVKEVEAKMEYTLM
                     RIPNVPHPEVPQGETDEDNVQIRTWGEPTKFDFEHKAHWDIGTGLGILDFERAGKITG
                     SRFTLYRGLGARLERSLMNFFLNTHTAKHGYTEVLPPFMANRNSFIGTGQLPKFEEDM
                     FKIEGLEYFLIPTAEVPVTNIHANEILDVAELPIKYCAYTPCFRSEAGSAGRDTRGLV
                     RQHQFNKVELVKFVKPEDSYNELESLTHDAETMLQMLGLPYRVVKICTGDLGFTAAFK
                     YDLEVWMPSYNRYVEISSCSNFEDFQARRAGIRFKRDKKSKAEYVHTLNGSGLAIGRC
                     LAAILENYQQADGSVVVPEELRPYMGVDVIK"
     misc_binding    complement(7431..7636)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(7764..8645)
                     /locus_tag="KR294_003317"
     CDS             complement(7764..8645)
                     /locus_tag="KR294_003317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HBH0241369.1"
                     /translation="MNFLSLAKTASTNSNITKRTLENMLDNFSDNIPNIIYAIIVFVI
                     GIYISKIVRRMVSKFLIKYGMSKGVNNFIVYGIYISMLSIISLISLGIIGIQTTSVVA
                     VLGAAGFSIGLAFKEILSNLGSGMIILFFKPFNIGDYIQGSGVEGTVSDIQIFSTVLK
                     TPDNKTIIIPNFQLTSNNIINYTHQNKRRIDFSYNISYDSDIDVVKSILNEIFTNEKR
                     ILNDPKPIIGLNSIGNNTMQIVARPWVKTDDYWDVYFDVMEKVKNKFDENDIKVPFVP
                     SSLLFNNTGNLNTMDKR"
     gene            complement(8657..9166)
                     /locus_tag="KR294_003318"
     CDS             complement(8657..9166)
                     /locus_tag="KR294_003318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HBH0241370.1"
                     /translation="MNSNERRSKLIDILKESKHPVKGGTLAELLNVSRQVIVQDIALI
                     RARGFEIIATPQGYIIYNQPYFTKQIKCKNHKDSKEIYDELKIIVDLGGIIKDVIVNH
                     PTYGQITAELNIYSKMDIDNFMKKVETNEFKQLSVLTECSHIHTIEAIKEETIEAIVK
                     ELKDNGILS"
     gene            complement(9292..>9407)
                     /gene="rrf"
                     /locus_tag="KR294_003319"
     rRNA            complement(9292..>9407)
                     /gene="rrf"
                     /locus_tag="KR294_003319"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         2993 a         1652 c         1010 g         3752 t
ORIGIN      
        1 ctcagatact attgttatca aaatatctgg ctttatggtt tgtttcttaa tataaattaa
       61 cctactgttt aattttcaat gttcgtgttt atttcttttt ccttttttca aggacaagta
      121 atactatatc atctttatct attctagtca atataatttt ttactttttt taattttttt
      181 atttatcatg tattctttat ctttaatttt taaaacttaa tgctaagtaa acctgtttat
      241 ttcataaaac taatatatat tctatgctct attttccttt ttattctata tttaaatttt
      301 ttatttacaa gaatattttt aatataacat atttgataaa attaatttac atttctttca
      361 cttgtaattt ttgcaatctt gtattagatt aatattaaaa ataatttatc aataacctta
      421 ttcacaaaga cagtttttat atatcaaaat ataatataaa tactatgcta cattttagga
      481 ggattttatt atgagcaaaa aagtattaat aatgtctgct tccactggtg gtgggcataa
      541 tagggctgct ctagctatta aagaagaact tacttccaaa acacttgatg gagagccaat
      601 tgaatgtgaa ataatagata gtttgaaatt agttaataat acaatggata aaataatttc
      661 aagaggatac gaaaaatctg ctatatatac tcccaaagcc tatggaagtg tatatagatt
      721 atctgaaaca aatcttttgt caaaaaatga atttaaagat aatctactaa taacattcat
      781 ggctaaaaaa tttaaaaagc ttattagaag cgaaaaacca gacttgatta taggaacgca
      841 tccttttcca atgattgctc taagtacatt gaaaaaaaac tttaatttac ataataatga
      901 atcaaatgct tacacagagc atttttataa acattataca aataccatta atgttcctcc
      961 gcttatttct gtattaaccg attatactac tcattctaca tggatacaaa atgaaattga
     1021 ttactatatt gttggtcatg aatatgtaaa agaattattg gtgtttgatg gagttgaacc
     1081 gagtaaaatt agaacatttg gaatccctgt tgaaaaatct tttctctctc acagagataa
     1141 agatattgtt ctttctgagt tgaatttatc tcctgataaa ttaactgttt tacttatggg
     1201 gggtagcttt ggggctggaa atataaaaga gacacttgat gaattactgg atactgatag
     1261 agactttcaa atacttgtaa ttactggtaa gaatgaaagc ctaaaagaaa aaatcgaaaa
     1321 aaaacttatg tctcgttatc atgataaaaa tgtatgtgtc cttggataca ctgataagat
     1381 gaatgatatt ttagcttcta tagatgtatt agtaagcaaa cctggtggac ttactacaac
     1441 tgaggctctt ttaaaagatg tacctatgat agttccttat tatataccag gtcaggaaga
     1501 agagaatctt gatttcttat ctaattgtgg tgcagcactt agaactacaa aaaaatataa
     1561 cttgtcaata ttactaaaag ttttaataga tgaccctagc agattagaaa tgctaaaaag
     1621 aaatattaaa tcaataagaa agtcaaattc agcccaaaat atagctaatt taattttaaa
     1681 tataatttct ggttgataaa ataaataaaa tccctatagt atatatatta tctattaggg
     1741 attttttatt ttctaattat ttaatattaa attggctcat aaaagtcttc ttcataatca
     1801 tactgataat ttttataatt atttctaaat tcagcatttt tatttcgtac atttttttta
     1861 gtttttttct tattagaaaa acttatatcc tcaaaatcat catatttagg tttatctttt
     1921 gatttcattt ttttaactct tttttctttc attgcattat gttcttctaa gttcataatt
     1981 ggtttcatgt tgcaccccta tcaaaatttt taaatgattt atacaacaaa ttatacaata
     2041 cagaagaaat ttattcaata aatctaaatc aaaattaatt tgaatttaac tcaaaaaact
     2101 acaaaaatcg aggtattaac ctcgattttt atatttctct tctgccttct agtgcttttg
     2161 atattgtgac ctcatctgca tactctaaat cgcctccaac aggaagacca tgagctatcc
     2221 gagtgacttt gattcccatt ggttttacta acctagcaat atacatggct gtagcttcac
     2281 cttcaatagt aggatttgtt gccattatta tttctttgac ttcctgattg ccaagtcttt
     2341 ggataagttc ctttattttt aacatatctg gtccaattcc atccattgga gaaattactc
     2401 catttaatac atgatactgt cctttaaact ctctcgttct ctccatagct gctacatctc
     2461 ttggatcttc cacaacacat ataacacttg aatctctact tttatttgaa cacatgctac
     2521 atgggtctgt atctgttata ttacaacaaa ttgagcaata tcttatttct ctttttgcat
     2581 ctataatcgc tttagataaa gcttccacat cattagtatt catattaata atatgaaaag
     2641 ccaatctttg agcagtcttt cttcctactc caggaagctt tgaaaattcc tctataagtc
     2701 tcgttatggg acctgtataa acttgcataa ataccaccta ctagaataac ccaggtatat
     2761 tcatacctcc agttacctta ctcatttgac ttgcttgtat atcatcaata tttctcaatg
     2821 cttgatttac tgcacttaaa actaaatctt gtagcatttc tatatcatct ggatcaacta
     2881 cttctggctt gatagttata tctataactt cttttttacc attaactttt acagtaactg
     2941 ctcctccacc aactgaagct tctacttctt tactttctaa ctcttgttga gctttttgca
     3001 tattttcttg cattttttga gcctgcttta acaagttgtt catatttcca ccaccaggca
     3061 tcattccgcc tccaaaacct tttttagcca taaacactat tcctcctaaa cttattttca
     3121 ttttattatt atatcataat agtattttat tatttactct cattttcatc aatactatct
     3181 tttatttcta atatctcttc actcactatg ttctttaata tttcctcacc aatgtccttt
     3241 ttctctttaa cttcaagatt tatatcttta acttctgatg tcagtactat ttttacatta
     3301 aaacttctat ttaaaacatc tcttattgtt ttttctaaat aatttattgt atcttgagag
     3361 ctcagtctag tttttgcaaa atcaaattta tcatcaaata taacatacaa catattagaa
     3421 tatacattaa aactttttac ttcacttaag agtgcgtata ttggcatttt tttatctttt
     3481 ttaatttgtt taagtatatt cttccaagat gactctataa gtataacatc ctcatttttt
     3541 acatcttcat aaactacatt ttcttgtttt acatctattt ctctatcgac ctcatactct
     3601 ttttctttat tattcccaat tttttcagac ttaaagttcc ccagttcaat cattttttct
     3661 aagttctcaa ctctttttat aagagcttct ttactttcat caaacattgg ttgagcaatt
     3721 ttcattatgg ttatttccac taaaaccctt ggatttgaag atgactttat atcatcctga
     3781 gttattgata atatatttaa aatccttatt aaatcattta tatctatatt tttagactga
     3841 attttaagtt gttctatagt ttcttctggt aatgaaatta tttcatccaa ttctgatgaa
     3901 accttacata ccattaaatt tctaaaatga tcaattaagt catttataag atttcttata
     3961 tctttgcccc ataagacaaa ttcatttaat atctcaagag actttttagt gtcctgctct
     4021 acaatacatt gagacaattc aaataattgt tctatattta cgcttcccat taattcaaca
     4081 acatctttat aatctatctt actttctcca aaagacatac attggtctaa tatactaagt
     4141 gcatctctaa gagctccttg agaatttcta gctattaaat taagagcttt atcatctata
     4201 tcaattcctt catcttcaca aatctttttc attctaaggg tcatatcttt aactgtaact
     4261 cttttaaaat cgtatctttg gcatcttgat aaaatggttg caggtatttt gtgaggctct
     4321 gtagttgcta atataaaaat tacatatgat ggaggttcct ctaaggtctt taataatgca
     4381 ttaaaagctc cttgagacaa catatgaact tcatctatta tatatacttt atatttagca
     4441 ttggctggag aatatttcac actttctcta agctctctta tatcatctac actattattt
     4501 gaagctgcat ctatttctac aacatccatt gtattatctt ttaatacaga ttcgcatatc
     4561 tcacactcat tacacggttc ttcatttatt ttattcaaac agtttactgc tcttgaaaaa
     4621 atctttgcag tagatgtttt accagtacct cttgttccac aaaacaaata agcatgtcct
     4681 atattatcac tatatatttg attctttaaa gtcttaataa tatgatcttg accaataaca
     4741 tcttcaaatt tttgtggtct atatgctcta tataatgctt tatgcatctt tttacctctc
     4801 tttagcaaaa ttaataaaaa aatccctcat tatctaaggg attagtcttt tatatattaa
     4861 atgctgtaca ccatctatcg acttaattcc ataggcgtta ccaaaacagt tagctcaact
     4921 taggcacccc cacggcacac aaaagtgatc acttaccgct gcttccttcc ggatctgacg
     4981 gggttcatga gctttcattg cgcaggacct aagcatcaac accacttatt tagggcggcc
     5041 ctacagaaaa taagccttta gatggaattc aatcctgcta tagcggattg caggttacag
     5101 ggcaccgcta cctccccatc tagtacagca aaattacaac catatttaat tactttcatt
     5161 gtttctggcg gagagagtgg gatttgaacc cacgatacag ttttacccat atactcgctt
     5221 tccaggcgag cgccttcgac cactcgacca tctctcctta atctcttttt ctcaatgcct
     5281 taaaaaattc ttgcaatatg atcgagcatt cttcttgcaa aacatcaaaa gctactttta
     5341 cattattatt attaaaataa tctaatttaa actcatgctg tttttctata tatgaatttt
     5401 ttacatgtct tgtccctatt ataagctttt ttattctaga attaactatt gcgccactac
     5461 acattatgca aggttccatt gtaacatata aatcacaatc agtcaacctc caaccaccta
     5521 atttttctga tgcttgtttt atcgctaaaa tttctgcatg tgccgtagag tcttttaacg
     5581 tttctgtaag gttatgagct ctagctatta tttgattatc tttaactata atagcaccta
     5641 ttggtgtttc ttttttatta tatgctttat atgcttcttt taatgcttct ttcatataaa
     5701 atgaactttc cataattcct cccaaaactt ataacaaact tatcttatca taattcattt
     5761 tataattcaa cttaatttta ttttgtttat ttaattatta ctatatatag ctatattttt
     5821 tttaaattag ttctaaaata atttttagat attcatacaa gagtgtttta taaaaatatt
     5881 tagtgtttta tgatgaaaat tctgctgtgt aaattaacat aaaaaaacta tgaaattaat
     5941 atttataata atttcatagt ttttttattt attgtttact cataatatat tctcttcatc
     6001 aaagcatact ctacatatac aattaatata aatttatttt ataacatcaa cacccatata
     6061 aggtcttaat tcttctggaa ctactacaga accatctgcc tgctgataat tttctaatat
     6121 agcagccaaa catcttccta tcgctaatcc agaaccattt aatgtatgaa catattctgc
     6181 ttttgatttt ttatcccttt taaatcttat tcctgctctt cttgcttgga aatcttcaaa
     6241 atttgaacaa gaagatattt ctacatatct attgtagctt ggcatccaaa cttctaaatc
     6301 atatttaaat gcagctgtaa atcccaaatc tcctgtacat atttttacaa ctctatatgg
     6361 aagacctaac atttgtaaca tagtttcagc atcatgagtt aatgattcta attcattata
     6421 agaatcttct ggtttaacaa atttaactaa ttcaacttta ttaaattgat gttgtctaac
     6481 taaacctctt gtatctcttc ctgctgaacc tgcttcagat ctaaaacaag gagtatatgc
     6541 acagtattta attggaagct ctgcaacatc taatatttca ttagcatgta tattagtaac
     6601 aggaacttca gctgttggta ttaagaaata ctctaatcct tctattttaa acatatcttc
     6661 ttcaaattta ggaagttgac cagtccctat aaaactattt ctattggcca taaatggagg
     6721 taagacttcc gtatagccat gcttagctgt atgagtattt aaaaagaaat tcattaaaga
     6781 tctttctaat ctagctccta atcccctata taaagtaaac cttgacccag ttattttccc
     6841 tgctctttca aaatctaaaa tacctagacc tgtacctata tcccaatgcg ctttatgctc
     6901 aaaatcaaat ttagtaggtt ctccccaagt tcttatttga acattgtctt catctgtttc
     6961 accttgtggt acctctggat gaggaacatt tggtattctc attaatgtat attccatttt
     7021 tgcttctact tcttttactt tctcatcaat accttttatc ttatctgata actctttcaa
     7081 tcttgccttt tcttctgtta catcttttcc ttcttttatt aattgaggta tttttttaga
     7141 atttacattt aactcatttt tcataacttc aacttcttga agtatttctc ttcttttatt
     7201 atctaattcc actacagcat caaggtcaaa ttctctttca cctcttcttt ccatagcttt
     7261 tttgatatca tctagatttt ctcttattct tttaatatct aacatattaa ttcctcctaa
     7321 taattttgat aatataagtt ataattccaa cttaatttac aaacattata cttgtaaact
     7381 cttagtttaa acaaatttta aaaataaaaa aagacctccg tttaccctat aaaagggacg
     7441 aaaatctttt atccgcgttg ccaccctaat tgactatact aaaatgtata atcctctcag
     7501 acctataacg taggtaaacg tctagcttta actagaagct ctagagtaga ttcaaaaacc
     7561 attgtaatga gttttcacca tccactcatt ctctgaatac aatctgtttt ttactatttt
     7621 ccttcacagc tttttaacta attgttttat ttgataatca ttatattata tatattaaca
     7681 tctttcaata ctattattca aattttttta gaattttctt taatttttta tattaaattc
     7741 attttttcta tttaattaag accttatctt ttatccattg tatttagatt acctgtatta
     7801 ttaaataata atgaagaagg aacaaatgga acttttatat cattctcatc aaatttattt
     7861 tttacctttt ccattacatc aaagtataca tcccagtaat catcagtttt tacccaaggt
     7921 ctagcaacta tttgcatggt gttatttcct atagagttta gacctattat aggctttgga
     7981 tcatttaata ttcttttttc gtttgtaaaa atttcattta atatagactt aactacatct
     8041 atatcactat catatgaaat attatatgaa aaatctattc ttcttttgtt ttgatgtgtg
     8101 taattaatta tattattact tgtcagttga aaattaggta taattatagt tttattatct
     8161 ggcgtcttaa gaacagtgct aaatatttgt atgtcagaaa ctgtaccttc tacacctgaa
     8221 ccttgaatat aatcacctat attaaatggc ttaaaaaata aaataatcat accagagcct
     8281 aaatttgata atatttcttt aaaagctaaa cctatactaa atccagcagc tcctaacaca
     8341 gctacaactg atgtagtttg tatccctata atacctaagc ttatcaatga tataatagat
     8401 aacatagata tatatattcc atatacaata aaattattta cacctttact cattccatat
     8461 ttgattagaa actttgaaac catccttctt actattttag atatataaat acctatcaca
     8521 aatacaatta ttgcatatat aatatttggt atattatcac taaaattatc gagcatattt
     8581 tctaaagttc tcttagttat attgctattt gttgaggcag tcttagccaa tgataaaaaa
     8641 ttcattcaac tcctccttat gataatattc cgttgtcctt taactctttt actatagctt
     8701 ctatagtttc ttcttttatt gcctcaattg tatgaatatg gctacattct gtcagaaccg
     8761 ataattgttt aaattcattt gtctcaactt tcttcataaa gttgtctata tccattttag
     8821 aataaatatt aagttctgca gttatctgac catatgttgg atgatttaca ataacatctt
     8881 ttataatacc acctaaatct acaattatct ttaattcatc ataaatttct ttagaatcct
     8941 tatgattttt acactttatt tgttttgtaa aatacggttg attatatatt atatatcctt
     9001 gaggtgtagc tattatttca aatcctctag ctcttataag ggctatatct tgaactatta
     9061 cttgcctact tacatttaat agttcagcta gtgttccacc ttttacagga tgcttagatt
     9121 cttttaaaat atctattaat ttacttcttc tttcattaga attcatatta caccttcttt
     9181 ccaaataaaa actttaccta tactatataa ttttatattt tatcttatta taaatcaata
     9241 ttgactttat attctattta atcttaactt ttataataaa taaaaaagac tacgtggcta
     9301 cgtcctactc tcccaggcag tttcccacca agtaccatca gcgctagaga gcttaacttc
     9361 tgtgttcgga atgggaacag gtgtatcctc tctgctattg taaccac
//
LOCUS       DAEPKC010000124         9232 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.125, whole genome shotgun sequence.
ACCESSION   DAEPKC010000124 DAEPKC010000000
VERSION     DAEPKC010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9232)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9232)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9232
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.125"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(370..666)
                     /locus_tag="KR294_003320"
     CDS             complement(370..666)
                     /locus_tag="KR294_003320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241371.1"
                     /translation="MYFKTYILKREVNNKQLEITRSFDLDNLICTATEILKDNEIDLI
                     ITNEVNNVVWRNEKSTPPARECLVIAIEVYWWYTSIFLLYHINYVIKKSYLNRF"
     gene            complement(685..1098)
                     /locus_tag="KR294_003321"
     CDS             complement(685..1098)
                     /locus_tag="KR294_003321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241372.1"
                     /translation="MKVKSKRSFIVGIIVCMLCCASLVIYCILKDKRFLISSFLLIVI
                     AIFNFCNAFSRKGIVEELHDSADERDLYLTMKTSHILVKIMNYTLFTFTFLFIIAYSA
                     WKNQSLLVIAITLCVIEIFLFVAYLLINIFLEKKE"
     gene            complement(1082..1315)
                     /locus_tag="KR294_003322"
     CDS             complement(1082..1315)
                     /locus_tag="KR294_003322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0241373.1"
                     /translation="MKTKVREFRTNMGLTQQQLADLVHVSNRTIISIEKEQYSPSLML
                     AYRMAQVFGTTIEELCCLKENKEMEDKKHESKE"
     gene            1534..1908
                     /locus_tag="KR294_003323"
     CDS             1534..1908
                     /locus_tag="KR294_003323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBH0241374.1"
                     /translation="MKISKLPEAELKVMRYICEANKVLTSRELVAAMEEKYEWNESTT
                     FTVLKRLERREFLSTEKIGKLTHYNILVKEKKYLRFETKEFLKNIHKNSISSLMSALH
                     GEDDEVDEDKLSELEEYFKNLK"
     gene            2520..3212
                     /locus_tag="KR294_003324"
     CDS             2520..3212
                     /locus_tag="KR294_003324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0241375.1"
                     /translation="MYNILVVDDDKEIVDSIEIYLKSEGFKIYKAYDGMKALEIITEN
                     DIHLILMDIMMPKLDGIKATVKIREERNIPIILISAKSEDTDKIIGLNIGADDYITKP
                     FNLLELIARVKSNLRRYVTLGNYEDTCKEILKSGALELNTLTKEVKIDGENIKMTPIE
                     YKIIELLLENKGRVFSIDEIYEKVWNEESFNSENTVAVHIRRIREKIEINPKEPRFLK
                     VVWGVGYKIEKF"
     gene            3408..5468
                     /locus_tag="KR294_003325"
     CDS             3408..5468
                     /locus_tag="KR294_003325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBH0241376.1"
                     /translation="MEKYRVLKLVSLIIISISFPLTILLVTIGLAEPKYNIQKTSTKS
                     GIFDISDDFYDSNIFDEGTMASLLPKFKLSVGGKLTSKEKGKFQQEGKSIDLSSSDSE
                     YDKIMINEQASEEYLSYLKNIKVYVINTYTGVFYTNTSYASLYDFKQKTKSYCNVEII
                     NKIGKSSYIKTINGEKFELNNLSLELNEVDEGFEAYVSFPEEPTIEDGIVYTNFQIFK
                     QATEKVRLFFVASLSLAIICLLSIILYIKIKGEVLKRNNVFLLIYSKIPMEFNVILVS
                     ISIAILTIYALAVSYHIDVIALVSLSLLIVSNNIFFINVQLSYLENKMCIFKTSIIVR
                     VILWLIKTVREVSNAIKKVSLARKVIVIVIISLALIMAISTRSIGMGLLFSICIFLGF
                     TIYITKRLSYLSYVIEGTERIKKGELDYKIKITGNDNFTSLAENINNIGEGLDRAIEE
                     QVKSERMKSDLITNVSHDLKTPLTSIINYVDLIKKEESIQPEYINDYINVLESKSKRL
                     KLLIEDLFEASRVSSGNIELQISKIDLVQLLRQSIGELEEKLSKNNLYLKLNVPNDKV
                     YIWADGRRMYRVFENLLSNIAKYSLEETRVYIDVYDYGENVKVTMKNISSYELNFDPS
                     EIMERFKRADESRNTEGSGLGLAIARDLVALQGGKFYIEIDGDLFKANLEFQKYEEEI
                     TNME"
     gene            complement(5674..5997)
                     /locus_tag="KR294_003326"
     CDS             complement(5674..5997)
                     /locus_tag="KR294_003326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HBH0241377.1"
                     /translation="MNNNYIFFIIIGMYIVTYLPRVLPMLIFSKKEMPDFLKKIMKFI
                     PVAILTSLTAKDVFFNGDSLYLSIANPKIISFMIVLLVAYKFKSIGISIITGVISIYL
                     FGIIL"
     gene            complement(5990..6691)
                     /locus_tag="KR294_003327"
     CDS             complement(5990..6691)
                     /locus_tag="KR294_003327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HBH0241378.1"
                     /translation="MERTQQLKESFIASIPIFLGYIPIGIVGGILLQKSGLSPFQIAL
                     MVTLVFGGSSQFIAASMISTGASVTSIVLTTFIVNLRHFLMSSNLNMYIKNKSPKFIL
                     PFCHTITDETFAVNYEKFTAGNWSDRNAIYLNFFCLISSVLANFIGAFLGESISIDSS
                     ISGFILTSMFIALIVSQIKNKIYIVVFISSIIISVILYALFKSNLVIIVASILASLIG
                     FFIEESYCKKEESYE"
     gene            complement(6969..8354)
                     /locus_tag="KR294_003328"
     CDS             complement(6969..8354)
                     /locus_tag="KR294_003328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBH0241379.1"
                     /translation="MPINSFENYPMNWKPKRPSKGQILYKALVEQLEQDINNGFLLPG
                     TKLPPQRELADFLDVNVSTISRAFKICEKKGLISGVTGSGTFVSYDTRSNLFLMSSNN
                     KITFIEMGTMNPDFTLEEMNTLFKHIIKEIDFKTIFQYGQRDGAKWQKEAIAKLIYKA
                     GLETTSDSLLPASGGQNAIVAILAGLFQHGDRIGVDPLTYPGIKTAAKMLGIQLIPIK
                     QEDNEISEEGLLYACKNENIKGLYIIPDYQNPTTHIMSQNGRKMIANIASKYNLIVIE
                     DAIHSLLNETHLNPVASYLPNQTIYITSLSKIIAPSLRLAYISTPKQYREALSSALYN
                     INLSQSYFLTEIAYRMITSGEADKLINARRKSARRRNKIINQYLSGYNLLGNEECIFR
                     WLILPDGIMAEKFEIQALKEGVQVYASERFAVGKEKPISAIRIAVCATESTEELKAGL
                     SVLKRLLEEKK"
     gene            complement(8800..9222)
                     /locus_tag="KR294_003329"
     CDS             complement(8800..9222)
                     /locus_tag="KR294_003329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HBH0241380.1"
                     /translation="MNTFKTEVLLKYSAKDIFNIFTKSARLNFPNFNEKKAVGTFVQQ
                     KNNKRFKVEITNFEKNRVYEIKTSNKRESTITRYELVHIDLENTKLIFIESESKRNIF
                     GKINSALVRVLFGKRQPEEFNKFIKKLEMELENNSVNL"
BASE COUNT         3561 a         1099 c         1277 g         3295 t
ORIGIN      
        1 agttttaggt ttaattaaat atattattgt agttcctatt ataactatta ttccaataag
       61 tataagattg atatttccaa aatccatagc agatacctcc tattaaattt gcttttctta
      121 atcaaagtat atcagtaaca caagtacaaa gagcatctaa aatattacaa atattaacag
      181 gatagataaa actatagtaa aaattgtaat aataaagcga acgaaaatta tcatactaaa
      241 acataagaca tgttataatt gtattagata gaagattaac atacaccaaa gcactcctta
      301 caataaagag tgcttatttt tttgaaattc atcaatatat aaactatcaa gaaccttatt
      361 caacacacct taaaatcgat ttaaatagct ctttttgata acataattta tatgatataa
      421 taaaaaaata gaagtgtacc accaatacac ttctatagct ataactaagc attctcttgc
      481 tgggggagtg cttttttcat ttctccaaac aacattattt acttcattag taattatcaa
      541 atcaatctca ttatctttca aaatctctgt tgcagtacaa attagattat ctaagtcaaa
      601 acttcgagtt atctctagtt gtttgttatt tacttctctt tttagtatat aagttttaaa
      661 atacatttat atcacccctt gtatttactc ttttttctct aaaaatatat tgataagtaa
      721 atatgcaaca aataaaaaaa tctcaatgac acatagtgtt atagctataa ctagaagtga
      781 ttgatttttc catgcactat aagctatgat gaaaagaaat gtaaaagtaa ataatgtata
      841 attcataatt ttaactaaga tatgacttgt tttcattgtt aagtacaagt ctctttcatc
      901 tgcactatcg tgtaattctt caacaatgcc ttttcttgaa aaagcattac aaaaattaaa
      961 gattgctatt acaattaaaa gaaatgatga aattaggaat cttttatctt ttaaaatgca
     1021 ataaataact aaactagcac aacataacat acaaactata atacccacta taaaacttcg
     1081 tttactcttt actttcatgt tttttatcct ccatttcttt attttctttt aaacaacata
     1141 gttcttcaat cgttgtacca aacacttgtg ccatacgata ggcaagcata agagaagggc
     1201 tatattgctc tttttcaata gaaataattg ttctgtttga tacatggact aaatcagcga
     1261 gttgttgctg tgttagaccc atatttgttc gaaattctcg tacttttgtt ttcattccat
     1321 aacctctttc tatatgaagc taacttcatg tgaagttagc ttcataatat cctaaaatga
     1381 gtaaaatgtc aatctcatta gataagtatt ataaaaccta aaagaataat atggtaaaaa
     1441 ttggatggaa ttatttacct taattctctt gtttgtaaaa ctttattgat atagaattta
     1501 acatatacat aaatcggcaa aggggcgcga attatgaaaa ttagtaaatt accagaagcg
     1561 gaattaaaag ttatgagata tatttgtgaa gctaacaagg tattaacttc tagggaatta
     1621 gttgctgcaa tggaagaaaa atatgagtgg aatgaatcaa ctacatttac agttttgaaa
     1681 agattagagc gaagggagtt tttaagtaca gagaaaatag gcaaacttac acattataat
     1741 atactagtaa aagagaaaaa atatctaagg tttgaaacaa aggaattttt gaagaacata
     1801 cataaaaatt caatttcaag tttaatgtca gcgttacatg gtgaagacga cgaagtggat
     1861 gaagataaat taagtgaact cgaagaatat tttaagaatt tgaaataaga aaatgacaaa
     1921 ttgatacata ataaataaaa tgaaggtatg aaattataac tttttctacc ttcattttgt
     1981 ttattattct gaacatgtta agaaaatgaa ataagtttgt attttagtta tataaatttt
     2041 aatagaatat gtacagtata tagtagatag aatgtataaa aatagaattt aaataagtag
     2101 ctattattgc agtgaaatga atgtttctaa gtatatttgg gtggaagaat ggtggaagaa
     2161 aattagtgaa atgtaattct tccaccattc ttccacccaa aaaataaaaa ctgttcaata
     2221 agaattaata tacatcaatt cagctgaatg caatcaaaat acttaaatga aagtaatctg
     2281 aaaacaacat aattcaaatc aatttattca aataaacctc aatttatctt aaatcttaag
     2341 aaatatttaa gaattaggat aatattttct taagatttat attttattat atagttataa
     2401 gggaaagtta caaaaatgta agccaaagta atataacaat ttagtcattg ttgagaaagg
     2461 gagtgaaaga tattgtataa tatagataag tattattata caatagagga agtgaaaata
     2521 tgtacaatat attagtagta gacgatgata aagaaattgt tgattcgata gaaatatatc
     2581 ttaaatcaga aggatttaaa atatataaag catatgatgg aatgaaagct ttggaaataa
     2641 taacagagaa tgacattcat ctaatactaa tggatataat gatgcctaaa ttagatggaa
     2701 tcaaagcaac tgtaaaaata cgagaagaaa gaaatattcc aataatttta atttcagcaa
     2761 aaagtgaaga tacagataaa ataataggat taaatattgg agctgatgat tatataacaa
     2821 agccatttaa tctattagag cttatagcta gggttaaatc aaacttaaga cgatatgtaa
     2881 ctttaggtaa ttatgaagat acatgtaaag aaattctaaa aagtggagct ttggagttaa
     2941 atacactaac aaaagaagtt aaaattgatg gtgaaaacat aaaaatgact ccaattgagt
     3001 ataaaataat tgaacttctt ttagaaaata aaggacgagt tttctcaata gatgagatat
     3061 acgaaaaagt atggaatgag gaaagtttta attcagaaaa tacagtagca gtacatatca
     3121 gacgaataag agaaaagatt gaaataaatc caaaagaacc aagattttta aaggtggtgt
     3181 ggggagttgg ttataagatt gaaaaatttt agtggaaaaa ttataaaaga aaagagttta
     3241 atatttaatt gcattttgat tttagtcatt tttacattta cacaaatgtt aggaatttta
     3301 atatgtttta attttttctc tgagagttta atttactcta tggggattat gcttttctta
     3361 aactttattt tatataaaat actgacaatg tagatgaggt gggcaacttg gagaaatata
     3421 gagtattaaa gttagtttca ttaatcataa tatctatctc atttccatta actatattgt
     3481 tggtgacaat aggacttgct gagcctaaat acaatataca aaaaacttct acaaagagtg
     3541 ggatttttga tatatctgat gatttttatg atagtaatat atttgacgaa ggaacaatgg
     3601 caagtctatt acccaagttt aagctatctg taggtggtaa attaactagt aaagaaaaag
     3661 gtaaattcca acaagaaggt aaaagtatag atttaagtag tagtgattct gagtatgata
     3721 aaatcatgat taatgaacaa gcttctgaag aatatttaag ttatctaaaa aatataaaag
     3781 tgtatgttat taatacatac acaggagtat tttatacaaa tacgtcatat gctagtttat
     3841 atgattttaa acaaaaaact aagagctatt gtaatgtaga gataataaat aagataggaa
     3901 agagctcata tattaaaaca ataaatggag aaaaatttga actgaataat ctgagtctgg
     3961 aactaaatga agtagatgaa ggttttgagg catatgtatc ttttccagaa gagccaacta
     4021 tagaagatgg aatagtatat actaattttc aaatatttaa acaagctaca gaaaaagtaa
     4081 gattattttt tgtagctagt ttaagtttag caattatatg tttattatct ataattttat
     4141 atatcaaaat aaaaggtgaa gttttaaaaa gaaataatgt atttttacta atatacagta
     4201 agatacctat ggaatttaat gtaatattag tatctatttc aattgcaatt ttaactatat
     4261 atgctcttgc tgtatcttat catattgatg taattgcatt agtttcttta tctttactga
     4321 tagtatcaaa taatatattt tttataaatg tgcaattgag ctatttagaa aataaaatgt
     4381 gtatatttaa gacaagtatt atagtaagag tgattttatg gttaataaaa actgtaaggg
     4441 aggtcagtaa cgctataaag aaagtatctt tagcaaggaa agttattgtt atagtgataa
     4501 tatctttagc tttaatcatg gcaattagca ctcgaagtat aggtatggga ttactgtttt
     4561 ctatatgtat ttttttagga tttacaatat atataactaa aagactttca tatcttagtt
     4621 acgtaataga aggtacagaa agaataaaaa agggagaatt agattataag ataaaaatta
     4681 ctgggaatga taattttacg tctttagctg aaaatataaa taatattgga gaaggtcttg
     4741 atagagctat agaagagcaa gtaaaaagtg aaagaatgaa gtctgacctt ataacaaatg
     4801 tatctcatga tttgaaaact ccacttactt ctataataaa ttatgtagat ttaattaaaa
     4861 aagaagaatc aatacaacca gagtatataa atgattatat aaatgtactt gagtcaaagt
     4921 caaaaagact aaaattattg atagaagatt tatttgaagc gagtagagta agtagtggca
     4981 atatagaatt acaaattagc aagattgatt tagtgcaact attaagacaa agtataggtg
     5041 aacttgaaga aaaattatct aaaaataatt tatatttaaa attaaatgtt ccaaatgata
     5101 aggtgtatat atgggcagat ggaagaagaa tgtatagagt atttgaaaat cttttatcta
     5161 atatagcaaa atattcctta gaagaaacta gagtctatat tgatgtatat gactatggtg
     5221 aaaatgtaaa ggtaactatg aaaaatatat cttcttatga attaaatttt gacccaagtg
     5281 agattatgga aagatttaaa agagctgatg aatcaaggaa tactgaagga agtggattag
     5341 ggcttgctat tgcaagagat ttagtagctt tacaaggtgg aaaattttat atagaaatag
     5401 atggagattt atttaaagca aatttagagt ttcaaaaata tgaagaagaa ataacaaata
     5461 tggaatgaga tagtatttaa gtatatatat tttttttact gtcgaaagct tttattataa
     5521 tatattagaa tatttacagt agagaatgaa gagtaaaaac agagtaactt taagtcactc
     5581 tgttttttat ttaaaatcaa taatataaca acttaaatta aaattgtaca catagtttta
     5641 aaataactta tacaataaaa cattatccaa atatcacaag ataattccaa ataaatatat
     5701 agatatcact cctgtaataa tagaaatacc aatagattta aacttatatg caacaagaag
     5761 tacaatcata aaagatataa ttttagggtt agctatagat aaatatagac tatctccatt
     5821 aaaaaataca tctttagcag ttaaggaagt aagtattgct acaggtataa atttcatgat
     5881 ttttttcaaa aaatcaggca tctctttttt tgaaaaaatt aacataggaa gcactcttgg
     5941 tagatatgta acaatgtaca ttccaattat aataaaaaat atataattat tattcataag
     6001 attcctcctt tttacagtaa gattcttcta taaagaaacc aattaaagat gctaaaattg
     6061 atgcaactat tattactaaa ttgcttttga ataatgcata taaaataaca gaaataatga
     6121 ttgatgatat aaatactaca atataaatct tattttttat ttgagaaact attaaagcta
     6181 taaacataga agtcaatatg aagccagaaa tagaactgtc tatagatata ctttctccta
     6241 aaaatgctcc aataaaatta gctaaaactg atgaaattaa gcagaagaaa ttaagataaa
     6301 tagcatttct atcagaccaa tttccagcag taaatttttc ataattaact gcaaaagttt
     6361 catctgttat agtatgacaa aatggcaata taaattttgg acttttattt tttatgtaca
     6421 tgttcaaatt agaactcatt agaaaatgtc ttaagttaac tataaatgta gtcaaaacaa
     6481 tagatgttac acttgcacca gtagaaatca ttgaagctgc aatgaattga gaacttcctc
     6541 caaatactaa agttaccatt agtgctattt gaaaaggtga aagaccagat ttttgtaata
     6601 gtattcctcc tactatacct ataggtatat aacctaagaa tataggaatt gaagcaataa
     6661 agctttcttt taattgttga gttctttcca caataaatca ctccttttgt attaaatgta
     6721 ttaaagtatt agtaaaacag aaaaatagat taattgtata attgcaatta taattaaaaa
     6781 taaatttgga ttaatatata aaatactata caacaaatag ataatcttaa acggttatta
     6841 aattttatct atttgttatt atgatgtaat aatacatatt aatctctata agttaattac
     6901 tatctggtgt aattttattt taacaacaaa aaaaaataca cacaattaaa atattgtgtg
     6961 caatacaatt attttttctc ttctaatagt ctttttaata cgctcaaacc agctttaagt
     7021 tcttctgtac tttctgtagc acatacagct attcttattg cagaaattgg tttttctttt
     7081 ccaacagcaa aacgttcaga agcatagact tgtacacctt ctttaagtgc ttgtatctca
     7141 aatttttctg ccattattcc atcaggtaga atcaaccatc taaatataca ttcttcattt
     7201 cccaaaagat tatatccaga taaatattga ttaataatct tgtttcttct tcttgcagat
     7261 ttacggcgtg cattaattaa tttatcggct tcacctgatg taatcatgcg ataagcaatt
     7321 tctgttaaaa aataagattg agatagatta atgttgtata atgcgcttga taatgcctct
     7381 cgatactgtt taggtgtaga gatatatgct agccgtaaac taggtgcaat aatttttgat
     7441 aaactcgtaa tataaattgt ttgatttggc agataggaag ccactggatt taaatgtgtt
     7501 tcattaagta aactatgaat agcatcctca ataacaatta aattgtattt agatgcaata
     7561 tttgcaatca tttttcgtcc attttgtgac attatatgtg tagttggatt ttgataatct
     7621 ggtattatgt atagaccttt aatattttca tttttacaag catataatag tccttcttca
     7681 ctaatctcat tatcttcttg tttaattgga attagttgaa tcccaagcat tttagctgct
     7741 gtctttattc caggataagt taatgggtct acacctattc tatctccatg ttgaaacaaa
     7801 ccagctaaaa tagcaacaat tgcattttgt ccaccacttg caggaagtaa gctatctgat
     7861 gtagtttcaa gcccagcttt ataaattaat ttggcaatag cttctttttg ccatttagca
     7921 ccatctcttt gtccatattg gaatatagtt ttaaaatcta tttccttaat tatgtgttta
     7981 aacaaagtat tcatttcttc tagcgtgaaa tctggattca ttgtgcccat ttcaataaat
     8041 gtaattttat tattactgga catcaagaat agatttgaac gtgtatcata agatacaaaa
     8101 gttccacttc ctgtaactcc acttattaga cctttttttt cacaaatttt aaaagctcta
     8161 gagatagtac tcacattaac atctaagaaa tctgccaatt cacgttgggg tggtaattta
     8221 gtacctggta ataaaaatcc attgttgata tcttgttcta gttgttctac aagcgcctta
     8281 tataatattt gcccttttga aggtctcttt ggtttccagt tcataggata attttcaaaa
     8341 gaattaattg gcataagttt tcacctcaca ttattaattt gattttttct ttatctaaaa
     8401 caataaattc taaagataca aataaaaact gataggaaat aattctatca gtttttgtct
     8461 tttaattgat ttcaaatctt cctataattt ttataccttc tttatcataa agagggattg
     8521 tttttttaaa tatattaaaa tttctttttc ttgtatataa aacagcttct tctggtgtct
     8581 ttggttggtt atcacaatcg tacaaatttc ttttttttaa ctaaaagcaa taatacataa
     8641 aattattatt gctaatgata ctcttaatgt ggtatatagt catagtgtca catgtctatc
     8701 aatagttttt tcagtaatta ttgtaacgaa tagtaggact cataaaatac ttagaaatat
     8761 gtttttagat aaattttaaa tatataatct aacttatatc tataaattaa cactattatt
     8821 ctccaattcc atttctagtt tttttataaa tttattaaat tcttctggtt gcctttttcc
     8881 aaacaatact cttacaagag ctgaattgat ttttccaaat atattcctct tgctctcact
     8941 ttcaataaaa ataagttttg tattttctaa gtcaatatgt actaattcat atctagtaat
     9001 agtactttct cttttattgc ttgtttttat ctcatatact ctattttttt cgaaattagt
     9061 tatttcaacc ttaaatcttt tattattttt ttgctgtaca aatgttccta ctgctttttt
     9121 ctcattaaaa ttaggaaaat ttagtcttgc agattttgta aatatattaa atatgtcttt
     9181 tgcagaatat tttaataaaa cttcagtttt aaatgtattc atatcgtttt cc
//
LOCUS       DAEPKC010000125         9217 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.126, whole genome shotgun sequence.
ACCESSION   DAEPKC010000125 DAEPKC010000000
VERSION     DAEPKC010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9217)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9217)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9217
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.126"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            702..1351
                     /locus_tag="KR294_003330"
                     /pseudo
     CDS             702..1351
                     /locus_tag="KR294_003330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429361.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase family
                     protein"
     gene            1892..3247
                     /locus_tag="KR294_003331"
     CDS             1892..3247
                     /locus_tag="KR294_003331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBH0241381.1"
                     /translation="MDTKISINENMSLGKRFFKYLAPSVVAMWVFSLYTMVDGIFVSK
                     GVGELALAAVNISMPFINFIFAVSLLFSTGASTIIAIYLGKKDIKSANEVFSFNLVSI
                     IILSIIILAITFFNLDRLALFLGATESTIGMVKDYLGIIIFFNGFFIVSYSLEVIIKT
                     DGFPILATVGVIISALTNIILDYLFVIEFGWGVKGAGIATGLSQVFSTIFFLIHFLRK
                     NSTLNFSKFRIDFKTLRKIVFIGFPDSTTELSCGIVVLLFNLSLTKYIGENALIYYSV
                     INYINTLVLMTMMGITQGMQPLTSFYYGAGNIDNVKKLLKMGIKATIIASVAVFAICM
                     AFSGPIVSLFIHPEETMLFNEGVRVFKIFSISFLLVGINVIISGFFVSVEKPSISTVI
                     SLGRGLVIVVLSLISMILIFGGQGIWMTTIVSEFICLILSLVFLKKNFSTLDSNLNKV
                     A"
     gene            complement(3365..4033)
                     /locus_tag="KR294_003332"
     CDS             complement(3365..4033)
                     /locus_tag="KR294_003332"
                     /EC_number="6.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphthine--ammonia ligase"
                     /protein_id="HBH0241382.1"
                     /translation="MKEVLKLADEKFVMSFSGGKDSILALNRMLKKGYKPVALLTTIS
                     EEHGKSWTHNLEYNMLKQVSSNIGLPLLVAECGVEGYEESFERALIKAKNMGATICAY
                     GDIDIESHRKWDTDRCEAVGMKVDLPLWQESREDLVYEFIDSGFCSVVTKVNLKHLGE
                     EFLGKKLTRELVEKIKNAGADPCGEHGEYHTFVVDGPIFKKPVEYEVKGTLIKDGYGY
                     LEIK"
     gene            complement(4100..4528)
                     /locus_tag="KR294_003333"
     CDS             complement(4100..4528)
                     /locus_tag="KR294_003333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HBH0241383.1"
                     /translation="MTKLWAIIFALLAGGSTALEAFINGELGKSTTALVATFISLTVG
                     AIFFLASIIVTGDLKCLVSINGFNYKLLLGGVFGGLIIYFTVKAIPNLGVSNTLILTL
                     VSQVLVGFFIDSVILGQETMHLYKYIGVILLILGTFFIVN"
     gene            4635..5228
                     /locus_tag="KR294_003334"
     CDS             4635..5228
                     /locus_tag="KR294_003334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HBH0241384.1"
                     /translation="MNFCYNCSIDFGGDFMYTNFNIDFNNFNKKENAIKFMLMGVLLI
                     ILGLLCLTFKTLGIKLISWTFGIALLFFAYLNLKNINELKRYATKEEIKPSINIQWVL
                     IIACILLFVFPQKIQSIFSLFLGFYLIFNQLVALVNSKNNPYSKFTTWNIVKILFGIC
                     LILSPLFLSRFIVSIMSFFIILFGLVLFFSGNTARKY"
     gene            5347..6282
                     /locus_tag="KR294_003335"
     CDS             5347..6282
                     /locus_tag="KR294_003335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893027.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HBH0241385.1"
                     /translation="MDKFKYAFDNKRYHTWNYYLRNTFGEKVFKVSINAGFTCPNIDG
                     SLGYGGCTYCSKEGSGDFAGNPKDNLISQFYNIKEMMLKKWPHAKYIGYFQAYTNTYA
                     PLEVLKEKYETILELEDVIGLSISTRPDCLPDDVVEYLSELNKRTNLWVELGLQTIHD
                     STSKIINRGHDYKTFVEGVEKLKSKNIKVVVHIINGLPGEDYNMMMETAKAVGKMGVD
                     GIKIHLLHVIKDTPMEKMLQNGMLTLMEQDEYINLVCDQLEILPETMIIHRLTGDGKR
                     DELVGPIWSLKKWEILNQIDDTLKARNSYQGCKFV"
     gene            complement(6553..7497)
                     /locus_tag="KR294_003336"
     CDS             complement(6553..7497)
                     /locus_tag="KR294_003336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HBH0241386.1"
                     /translation="MGEKSKGYVFIAIAGLLWATLGLFGKFLMGNGLTSEQVAFTRLF
                     FGFIVLGVYSSIRTPQILKISKKGIIYSVIIGIICQAMFNLCYFKAIDIAGVSIAAVL
                     LYTSPLFLAIFSKICYKENITRSKLFSLILCFIGAIMAVTGGRLDFQGLNAFGLLLGV
                     LSAIAYALMPTISKNALKEFSSSTILVYSFLFGAIFMIPSSRPWEILNYAKDLDVLSC
                     MLMLGIVPAALAYIFYAAGISKGVELSVAGVVASVELVGSVIIGCTILGESFSLGKLF
                     GVMLMLISAVVALNLSYDEIRIFYKSNKLKQIEKTESI"
     gene            7815..>9217
                     /locus_tag="KR294_003337"
     CDS             7815..>9217
                     /locus_tag="KR294_003337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH0241387.1"
                     /translation="MNLDLEFYQKILEASHDEICVSDDKGIIIYCNKAFEENYGLKKE
                     DILGKNVSFLEDSGYSTKSPIPIVLKTKTKFSLEQDTQTGKKLIITATPIFDENGNLE
                     FTVENCRDITELNNIKNKLEDTKKQVKKYKSEVETLYRTALRIEDTVIMDGIVMRPII
                     NTVNHVSKTDVSVLLLGESGTGKSSLARYIHHNSNRSNGPFITINCATISPQLLESEL
                     FGYTSGAFTGASTKGKVGLVELANGGTLFLDEIGDIPQNLQAKFLQLIQDRTFTPVGS
                     LKNKKVDIRIISATNVDLVSKVKEKKFREDLYYRLNVIEIKLPPLRERRDNLVEIIKY
                     YFNRYSSDFNLNKTISKEAMDAIANYRFPGNIRELQNIIQKILLTCTDNHITIDDLPN
                     ILTKNIHITNNGNKTHISQINKVIISDSKSTNYKNKNFDTLIKEYEKNIILDAYEKFG
                     SSYKVAKHLEISQSKAN"
BASE COUNT         3407 a         1296 c         1136 g         3378 t
ORIGIN      
        1 caaagataat atttagtaaa aataactttc attttaacta aacttaaaat tcaattactc
       61 tctaaattga cgtttaggaa ttagttcaaa ataaaaaaga gtgtatatat tgaaattact
      121 acatttcaat atatacactc tttttaaatt tctcagtttt ccatggaact ttactttatt
      181 tatttctgta ttagttgtat tttttatgca tttttcttta aaatcatatt ttctgattca
      241 actcttatat tataaaattt ctttactaaa ttattctctt tttctatatc ttcatatata
      301 ttttttaatc gccttttacc taatctttta tctaacatta ctaatgattt aactaatata
      361 ttatatgatt ttatcgcatc ttctattgag atatttaaac atatatttac tgcttcataa
      421 aaatcaaatt cattaaaaaa tccattttta tttacaatct tatatccctt tgcatctctt
      481 tctaaatact cttcctaaat actcttcaaa actttcatca tctaatctaa atcctatatc
      541 actatgaaaa ataggttttg catttggata tagttctatt gttttatcaa aagtttcgaa
      601 taccaagtta ttattattcg attttccaac agtccactat aaacaataat aagtttgttg
      661 ctccaaataa tgtaacactt gtagaaagat gttacagata tataaaagat agagaatgta
      721 gtttttctcc taatactatt agaaatagaa aaaatatgat taaaaatcaa attgaagttt
      781 tctttaaaga tatgaaatta atagatataa ctccttctat tttacagtct tatataaata
      841 acatatacaa tgagcacatg ttaaattcaa caaaaaacca agtcgatttt ataaaatcag
      901 tattgaaaga atcttataga ttaaaagaaa tatcagaaaa tatttgtgat tttgttacaa
      961 ccccaatcaa aaaaaatagt tcaacttcta agctttatac aaaacaaaaa gctcaattat
     1021 tattagaaaa atcaaaaaat attcctatag gtataccaat ttttttgatg ctaactcttg
     1081 gattacgttt tggtgaagct gtatcactta tatggtcaga tgtagacctt gataaaaaat
     1141 ctcacatgta aatcaaacat tagtttatgt atacaataaa ataatcttca aaggccctaa
     1201 aacccctaga ttcaaaagaa gattatttgt tcctgatgaa cttataagtt tgtttaaagg
     1261 ggaaaaatta aaacaaaata agttaaaatt acagggtata ttgaaaaatg aatttgattt
     1321 gatatgctta aataaaagat tcaacccgtg agttcaacca acttttgttg ttcattttaa
     1381 aaaactatta agagataata atcctagaga tataaaagta catgaattaa tacatgcaaa
     1441 tgcgactttg atattacttt caggtactaa cataaaagct atttataaaa tattagtaca
     1501 tgcagatata aaaatagcta tgaatatata ttccatattc tcacttatta gatgaaatga
     1561 ataaagaaac atctgaaaat ataagcaaaa tactattcaa ataatgttca gttttatgtc
     1621 aattaaatgt cactcaaagt gctttttttc catttgtcag ttaaatgtca cttaaagtac
     1681 ctttttccta tttgtcagtt aaatgtcagt aatatataaa taagatatat ttataagacc
     1741 cttaaaatca ctattattta ataaaattta taattatata ctatttgctg ttgacattgg
     1801 tattatacca tagtttatca tttatattag aataaaatta ttaattaata gtttcgtaat
     1861 tttataatag atttacaggg agtgataata aatggataca aaaatatcta taaacgaaaa
     1921 catgagtcta ggtaaaagat tttttaaata cctagcacca tctgtagttg caatgtgggt
     1981 tttctcacta tatacaatgg ttgatggaat atttgtaagt aaaggagttg gagaattagc
     2041 tttagctgct gtcaatatat caatgccttt tattaatttt atatttgcag tttctctatt
     2101 attttcaact ggtgcatcta ccataattgc aatctatctg gggaaaaaag atattaaatc
     2161 tgctaacgaa gtcttttcat ttaacttagt atcaataatt atattatcaa taattatatt
     2221 agctataact ttttttaatt tagatagatt agcactattt ttaggagcta cagaatctac
     2281 aattggtatg gttaaagatt atttaggaat aataatattt tttaacggat tctttatagt
     2341 gtcttattct ttagaagtta taataaaaac tgatggcttt ccaatattag ctactgttgg
     2401 tgtaataata tctgctctta caaacatcat acttgattac ttgtttgtaa ttgaatttgg
     2461 atggggtgta aaaggtgctg gtattgcaac tggtttgtct caagtctttt ctactatttt
     2521 cttcttaata cattttttaa gaaaaaactc tactttgaat ttttcaaaat ttagaattga
     2581 ttttaagaca cttagaaaaa ttgtatttat aggttttcct gattcaacta ctgaattaag
     2641 ttgtggtata gttgttttac tttttaactt aagtcttact aaatatattg gagaaaatgc
     2701 tcttatttat tatagtgtca taaattatat aaatacatta gtacttatga ctatgatggg
     2761 tataactcaa ggtatgcaac cacttactag cttttattat ggtgcaggaa atatagataa
     2821 tgtaaaaaaa ttattaaaaa tggggataaa agccacaata atagcatcag ttgctgtatt
     2881 tgcaatttgt atggcttttt caggaccaat agtctcttta tttatacatc cagaagaaac
     2941 aatgctattc aatgaaggag ttcgtgtatt taaaatattc tctatatctt tcttattggt
     3001 aggaattaat gtaataattt ctggattctt tgtatcagta gaaaaaccat caatttctac
     3061 tgttatatct cttggtagag ggcttgtaat agttgtttta agtctaattt caatgatact
     3121 aatatttggt ggacaaggaa tatggatgac tactattgtt tctgagttta tatgtcttat
     3181 tttatcatta gtttttctaa aaaagaattt ttctacatta gactctaatc taaataaggt
     3241 tgcttagatg ataagagtga caatatatga aaatatctaa ataaaaaata cctattatac
     3301 aatcttgcaa atattaaacc tttgcaaaaa ttaggattat ataataggta ttttatttat
     3361 gtaattattt tatttctaaa tatccatagc catcttttat taaagttcct tttacttcat
     3421 attctacagg ttttttaaat attggaccat ctacgacaaa tgtatgatac tctccatgtt
     3481 ctccacatgg gtctgcacca gcatttttta tcttctccac aagttctcta gttaattttt
     3541 ttcctaaaaa ttcctctcct aagtgcttta agtttacttt tgttacaaca ctacaaaatc
     3601 cactgtctat aaattcatat actaaatcct ctctactctc ttgccataat ggtaaatcta
     3661 ctttcatacc aactgcttca catctatcag tatcccattt tctatgactt tctatatcta
     3721 tatctccata tgcacatatc gttgctccca tgtttttagc ttttattaaa gccctctcaa
     3781 agctctcttc atatccttct acgccacact cagcaactaa taaaggtaat cctatgttgc
     3841 tacttacttg cttaagcata ttatattcta aattatgtgt ccatgacttt ccatgttctt
     3901 cacttatagt tgtcaagagt gccacaggct tatatccttt tttcaacatt cgatttaatg
     3961 ctaatatact atccttacca ccactaaatg acattacaaa tttttcatca gccaatttta
     4021 acacctcttt catctaactt tgttttatta acataattat accaaatttt tgagttgcat
     4081 agcaaattat attaaattgt taattcacta taaagaatgt ccctaatatt aaaagtataa
     4141 cccctatgta tttgtataaa tgcattgttt cttgtcccaa aattacgcta tcaataaaaa
     4201 atccaactaa aacttgggat acaagagtta atataagtgt atttgatact cctaaatttg
     4261 gaattgcctt tactgtaaaa tatattatta gacctccaaa tactcctcct aataacaact
     4321 tataattaaa accatttata gatactagac actttaagtc acctgtaact attatacttg
     4381 ccaaaaaaaa tattgctcct acagttaagc ttataaaggt ggccactaat gctgttgtac
     4441 tttttcctag ctctccattt ataaaagctt caagagctgt agaaccacct gctaataatg
     4501 caaatattat tgcccataat tttgtcatgg acaaacctcc ttctatataa ttctattaat
     4561 agaagtttat gatacaacct attaattaat tactaagtat agtttaattt ttatacacta
     4621 ggctttattt ggatatgaat ttctgttata attgttctat cgattttgga ggtgatttta
     4681 tgtacacaaa ttttaatatc gattttaata actttaataa aaaagaaaat gctattaaat
     4741 ttatgttaat gggagtatta ctcattatat taggattatt atgccttaca tttaagacat
     4801 taggtataaa attaatttct tggacttttg gtattgcact tttattcttt gcatatttaa
     4861 atttaaaaaa tattaatgag ttaaaaagat atgctactaa agaagaaatt aaaccctcta
     4921 ttaatatcca atgggttcta ataattgcat gtatattact ttttgtattt cctcaaaaaa
     4981 tacaaagcat attttcatta tttttaggat tttatttaat ctttaatcaa ctagtagcac
     5041 ttgtaaatag taagaataat ccttattcta aatttacaac ttggaatata gttaagattc
     5101 tatttggtat atgccttata ttatctccac tttttttatc tagatttata gtatcgataa
     5161 tgtctttttt cataatatta tttggactag ttctattttt ctctggaaat acagcgagaa
     5221 aatattaatt attttctcgc tgtattttta tattacttaa aatagaattt gtttaagtta
     5281 tctatttgtg gtaatatgtt ttttgtacaa gctcagcgta caattttatt agaaataggt
     5341 gattttttgg ataaatttaa atatgctttt gataataaaa gatatcatac ttggaattac
     5401 tatcttagaa atacttttgg agaaaaagtt tttaaggtat ctataaatgc aggatttact
     5461 tgcccaaaca ttgatggaag tcttggttat ggcggatgta cctattgtag caaagaaggc
     5521 tcaggtgatt ttgctggaaa ccctaaagat aatcttatca gtcaatttta taatataaaa
     5581 gaaatgatgt taaaaaaatg gcctcatgca aagtatattg gctactttca agcctataca
     5641 aatacgtatg ctcctcttga agttttaaaa gaaaaatatg agactatatt agaacttgaa
     5701 gatgtcatag gtctttcaat atccacaaga cctgactgtt tgccagatga tgttgtagaa
     5761 tacttatctg aactaaataa aagaaccaat ttatgggttg aacttggact tcaaacaatt
     5821 catgattcta catctaaaat tataaataga ggtcatgatt ataaaacatt tgttgaaggt
     5881 gttgaaaaac taaagtctaa aaatataaag gttgtcgtac acattataaa tggtcttcct
     5941 ggtgaagatt ataatatgat gatggaaaca gcaaaggcag ttggtaaaat gggtgtagac
     6001 ggtataaaaa tccatctatt gcatgttata aaagatactc ctatggaaaa gatgttacaa
     6061 aatggtatgt taactcttat ggaacaagat gaatatatca atcttgtctg tgaccaatta
     6121 gaaatacttc ctgaaactat gataatccat agactcactg gtgatggtaa gagggatgaa
     6181 ctagtaggtc ctatatggag cctaaaaaaa tgggaaattt taaatcaaat tgatgatact
     6241 ttaaaggcta gaaattctta tcagggctgt aagtttgttt aatacaaaat aataactata
     6301 gaaatggtta tataaatata gtcctttcta tagttattta gtatttacaa aacaaaatat
     6361 taatttgtac atttatacaa tatataataa aaaatagata gtctaaactg tatctactta
     6421 tattttattt gtactgtcca ctttattcta taaaatttat aaatagttat tttttaatac
     6481 caaatataat ttggtataat ttttgttgga ctctaaaatg tataccaata aatccttttt
     6541 aagtatataa ttctaaatac tttcagtttt ttcaatctgc tttaacttgt tggacttata
     6601 aaatattctt atttcatcat aagaaagatt aagtgctact actgcagata ttaacatcaa
     6661 catcactcca aataacttcc ctaaggaaaa actttctcct aatatagtgc aaccaattat
     6721 tactgaacca actaattcta ctgatgccac aacacctgca actgacaact ctacaccttt
     6781 agatatacct gctgcataaa aaatatatgc aagtgcagct ggaacaatgc ctaacattag
     6841 catacaagat aaaacatcta aatccttagc ataatttaag atttcccaag gtcttgaaga
     6901 aggaatcata aatatagctc caaataagaa actgtatact aatattgttg aacttgaaaa
     6961 ttcctttaaa gcatttttac taatagttgg cataagtgca tatgctattg ctgataatac
     7021 cccaagtaaa agtccaaaag cgtttaaacc ttgaaaatcc aaacgtccac cagtcactgc
     7081 cataattgca ccaataaaac aaagaataag tgaaaataat ttgcttctag taatattttc
     7141 tttataacat atttttgaaa atattgctaa aaacagtggt gatgtatata gtaaaactgc
     7201 tgcaattgat acacccgcaa tgtcaattgc tttaaaataa cataaattaa acattgcctg
     7261 acatataata cctattatta ctgaatatat aattcctttt ttgcttatct ttaagatttg
     7321 tggtgtcctt atagatgaat atacgcctaa aactataaat ccaaaaaaca atcttgtaaa
     7381 tgctacttgt tctgatgtca gtccatttcc cattaaaaac tttccaaata atccaagtgt
     7441 agcccataat aaccctgcta ttgctataaa tacataccct ttactttttt ctcccatttt
     7501 aaattccctt ctatttttat ttagtcaatt tacactcttc tttttaagca aaaactatgc
     7561 catcttaaat caatatatat cgactctaaa accctagtct ttccaataat actaataaat
     7621 tttcaatttt tttatattta tttttcactt actttaagtt gatttagact tattttaatt
     7681 gtaaaatgag ttatatataa cttatttaaa gttaaaatag actgaaactt atatataaat
     7741 atcaaatttt aagtatatta atcaattaaa cctattttaa tatatcatta aaaatttagg
     7801 aggaaaatat aaaaatgaat ttagatttgg aattttatca aaaaatatta gaagcttccc
     7861 atgatgaaat atgtgtttct gatgataaag gaataataat atattgtaat aaagcatttg
     7921 aagaaaatta tggtctaaaa aaagaagata ttttaggaaa aaatgtttct tttttagaag
     7981 actctggata ttcaacaaaa agccccatac caattgtatt aaaaacaaag actaaatttt
     8041 cactggaaca agatactcaa acagggaaaa agcttatcat aactgctacc cctatatttg
     8101 atgaaaatgg aaacttagaa tttactgttg aaaattgtag agatataact gaacttaata
     8161 atataaaaaa taaacttgaa gacacaaaaa agcaagtaaa aaaatataaa tctgaagtag
     8221 aaacactata cagaactgca cttagaattg aggatactgt aattatggac ggaatagtta
     8281 tgagaccaat cataaacaca gtaaatcatg tttctaaaac ggatgtaagt gtacttttat
     8341 tgggtgaatc tggaacagga aaaagctcac ttgctagata tatacaccac aacagcaata
     8401 gatctaatgg cccatttata acaataaatt gtgcaactat atctccacaa cttcttgaat
     8461 ctgaactttt tggatatact tcaggtgctt ttacaggtgc aagtactaaa ggtaaagttg
     8521 ggctcgtaga attagctaat ggaggaactc tttttttaga tgaaatagga gatataccac
     8581 aaaatctaca ggcaaaattt ttgcaattaa tacaggatag aacttttact ccagttggga
     8641 gcttaaaaaa taaaaaggtc gatataagaa ttatatctgc tacaaatgtt gatttagttt
     8701 caaaagtaaa agaaaaaaag tttagagaag atttatacta tagattaaat gttatagaaa
     8761 taaaattgcc tcctcttaga gaaagaaggg ataatctagt ggaaattata aaatattatt
     8821 ttaataggta ctcaagtgac ttcaatctaa ataaaactat ttctaaagaa gctatggatg
     8881 ctattgcaaa ttatagattc ccaggcaata taagagaatt acaaaatata attcaaaaaa
     8941 tcttgcttac ttgtacagat aatcatataa caatagatga cttaccaaac attcttacaa
     9001 aaaatataca tattaccaat aatggaaata aaacacatat atcccaaatt aataaggtta
     9061 ttatatctga ctcaaaatct actaattata aaaataaaaa ttttgacact ttaattaaag
     9121 agtatgaaaa aaatataatt ttggatgctt atgaaaaatt tggtagttct tataaagtag
     9181 ccaaacacct tgaaatctca cagtctaaag ccaatag
//
LOCUS       DAEPKC010000126         9164 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.127, whole genome shotgun sequence.
ACCESSION   DAEPKC010000126 DAEPKC010000000
VERSION     DAEPKC010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9164)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9164)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9164
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.127"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            213..779
                     /locus_tag="KR294_003338"
     CDS             213..779
                     /locus_tag="KR294_003338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HBH0241388.1"
                     /translation="MRKLEEILEYNKSFVENKEYEQYVTSKHPNKKIVVLSCMDTRLT
                     ELLPKAMNLKNGDVKLIKNAGATIMHPFGSIMRSVLVAIYEFDVDEVMVVGHHGCGMC
                     NVDTDKLLGKILDRGISNDVILTLRSAGIDTKQWLHGFDSAEESVKDSIDLIKGHPLI
                     PDGIIVHGLIISPETGKLDVVVNGYEDK"
     gene            1084..1545
                     /locus_tag="KR294_003339"
     CDS             1084..1545
                     /locus_tag="KR294_003339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBH0241389.1"
                     /translation="MNSNSEEKLNDVFLQLMRIYFIRTHFYFDKLGLYHGQPQILFSL
                     KMKDGQSQKELADKRKVKASTTTVMIKRMEKAGLVERKQDEKDQRVSRIFLTDKGLEI
                     CNKVEEFNKELEREFFLGFSEEEKIVLRRLLMQVRDNLKAGCHKHEDEKYF"
     gene            1613..3859
                     /locus_tag="KR294_003340"
     CDS             1613..3859
                     /locus_tag="KR294_003340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011009877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0241390.1"
                     /translation="MFKLIKYLKKSALSIVIIVCLLVIQAVCDLSLPEYTSNIVNVGI
                     QQGGVENSVPSVIRESELNKITLFMDKSSKDKVLDNYTLLNKKDYVKYKDKYPGLKDE
                     SLYELNTKDKDTIDDLNVIFGKAILIVSGLEGDSKEVKAMKAQLMSKLPPQATQSGDV
                     DIFKLLSAMPKEQLDTLTKEMSKGFESMPESMITQSSVSYVRSEYEKIGIDTEKTQNN
                     YILFTGAKMLGIAMISMVATITVGFLAARVAASVGRNLRSGVFRKVMSFSNTEMNEFS
                     TASLITRSTNDIQQIQMLMVMLLRIVFYAPIMAIGGVIKVLNTNTSMAWIIAVAVVAI
                     LSLIVVLFSVVMPKFKLVQKLVDKLNLVSREIITGIPVIRAFSTEKHEEERFDKANKN
                     LTKTNLFVNRVMTCMMPAMMLIMNLITVLIVWRGAYSVDSGAMQVGDMMAFIQYTMQI
                     IMSFLMISMVSIMLPRASVSATRIDEVLVSDISIKDPEKSEAQEFKEDKKGLVEFKNV
                     SFMYPDAEEPILTNISFTAKPGETTAFIGSTGSGKSTLINLIPRFFDVTEGEILLGGV
                     NIKNVSQHDLREKIGYVPQKGVLFSGTIESNLKYGRKDATDEEMRTAAEIAQATEFID
                     SKPEAFKTEISQGGTNVSGGQKQRLSIARAIAKNPEVYIFDDSFSALDLKTDAALRKA
                     LKSKTAESTVLIVAQRISTILNAEQIIVLNEGEIVGIGTHKELLKNCEVYEQIALSQL
                     SKEELANE"
     gene            3852..5684
                     /locus_tag="KR294_003341"
     CDS             3852..5684
                     /locus_tag="KR294_003341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0241391.1"
                     /translation="MSRMGRGPMGKSMGAGQKANDFKGTMRKLIAYLSKFKISIILVI
                     VFAIGSASFSIVGPKILGKATTKIFEGLVSKVSGGNVGIDFNAIGKILTFLLFLYLIS
                     ALFSFIQGFIMSGISQKVSYNLRKEISAKLDRLPMKYFDTKTHGEILSRITNDIDTLN
                     QSLNQSMTQLITSVTTMIGVLIMMLSISGIMTLVAVLILPISMFVISRIIKKSQKYFR
                     YQQEYLGNVNGQVEETYSGQTIVKAFNREDEVIEEFDKLNDSLYNSAWKSQFLSGIMQ
                     PLMMFIGNLGYVMVSILGGWLAIKKTIEVGDIQSFIQYVRNFTQPMTQIAQVANLLQS
                     TAAASERVFEFLEEEEEVQIVENAVSIDGLEGKIDFENVNFGYNPNKTIINDFSVNVE
                     PGQKVAIVGPTGAGKTTIVKLLMRFYDVNSGSILIDGHNIKDFNRSELREMFGMVLQD
                     TWLFSGSIMENIRYGKLNATDEEVIEAAKSAHVHRFIKTLPDGYKMKLNEEASNVSQG
                     QKQLLTIARAILADPKILILDEATSSVDTRTEVLIQKAMDNLMEGRTSFVIAHRLSTI
                     RDADMILVMNEGDIVEQGNHEELLKKGGFYANLYNSQFEEDEAM"
     gene            6403..7680
                     /gene="hflX"
                     /locus_tag="KR294_003342"
     CDS             6403..7680
                     /gene="hflX"
                     /locus_tag="KR294_003342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HBH0241392.1"
                     /translation="MDMAKKGITVGLNINNKSEDFNELMIELENLCSACDIDVVGSIT
                     QNAKQVNRAFYIGTGKVEEILNLIKKENIEIVIFYNELSTSQLKNLEEKLNCEIIDRT
                     ALILDIFAQRAKTREAKLQVEVASLKYMLPRLIGSNENLGRQSGGVGTKNRGSGEKKL
                     ELDRRRIEEKITSLNRELDDLKFQRETQRSMRRKSNLPNVALVGYTNAGKSSIMNKLV
                     DIFKNSEEKKVFEKNMLFATLETSVRNIVLANNKEFLLSDTVGFVSNLPHDLVKAFRS
                     TLEEACEADVLLHVIDISNPSYKSHIKVTEDTLKQIGADGIPMIHVYNKIDLIDVDVL
                     DRILDSIDKEGIFVSVKKDINIDKMIKCICDSIFKDYVRCKFLIPYDKGHVVSYFNEN
                     MSIINTEYREDGAILDVECSNIEYNKYKKYALE"
     gene            7913..8410
                     /locus_tag="KR294_003343"
     CDS             7913..8410
                     /locus_tag="KR294_003343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBH0241393.1"
                     /translation="MDAETLMKKYMVDDDSRKQAIFASIFVMQNKLQTTCDKLDPELT
                     MKQWLLLAIADSVDETLTLTKLGELMGCSRQNVKKLAIALEKKGFIQIEQNEKDSRAI
                     CLVTKDRVQEYSKKVRGMQEKVLQLLFEDFTEKEVEQLFFGIMKLSIGIENVKNYVEN
                     NDVGE"
     gene            8460..8984
                     /locus_tag="KR294_003344"
     CDS             8460..8984
                     /locus_tag="KR294_003344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HBH0241394.1"
                     /translation="MKNVVVIYKSKYGSTKKYAKWLSELLSCDIFETKNINIEKVMKY
                     DTIILGGGLYACNIAGISFLKKNYKELQKKNLVVFGVGAAPYDDEVIKKLREVNFKDE
                     LNKIPCFYCRGAWDETKMSFIDYTLCSFFKKSIAKKERQGLKPAEAPLLSGEAFDWCN
                     KENLTPILDYIREL"
BASE COUNT         3650 a          910 c         1639 g         2965 t
ORIGIN      
        1 aattaaaaaa ataatgaaaa tatataatat tagtttagat tataaaaaat aaatatacaa
       61 atacttataa atacaagtta tatacaagat ttatagtaga gtaataatct tataaaataa
      121 tttaataaat ataaattaaa ttatatgtgt atatattgta ctttaatagt gatataataa
      181 taaaaaaatt tttaaagagg gtgatattac atatgagaaa acttgaagag atattagaat
      241 ataataaatc atttgtagag aacaaagaat atgaacaata tgtgacatca aaacatccaa
      301 ataaaaaaat agtagtctta tcttgtatgg atacaagatt aactgagctt ttgcctaagg
      361 ctatgaattt gaaaaatgga gatgtgaaac taataaaaaa tgcaggagct actataatgc
      421 atccttttgg aagtattatg agaagtgttt tagttgcaat ttacgaattt gatgtagatg
      481 aggttatggt tgtagggcat catggatgtg gtatgtgtaa tgttgatacg gataagttac
      541 ttggtaaaat tttagataga ggaatatcta atgatgtaat acttacactt cgtagtgctg
      601 gaattgatac aaaacaatgg ttacatggat tcgattctgc agaagaatct gtaaaagata
      661 gtattgattt aataaaaggg catcctttaa ttccagatgg tattattgta catggtctaa
      721 ttatatcacc tgaaactggg aagttagatg ttgttgtaaa tggatatgaa gataagtaga
      781 gtatcataat gttatataat caagatactg ttgaataaga tgttgtttca aaatttattt
      841 tgggacaact tttttatttg aaaatatatg aaaaggttta ttttaagctt tacaataaaa
      901 aatataagta gctgactaat taaaaatctt actattattt attaaaatta taactatatg
      961 atataaaaat atttaataaa tgaaatttat atgaattttt tataaatata ttgaaaaaat
     1021 gcatgcagta tagtaaaata atgcttagcc gactaagtaa tataaaaaat aaggagggca
     1081 agtatgaata gcaattctga agaaaaatta aatgatgttt tcttgcaatt aatgcgaata
     1141 tattttataa gaactcattt ttattttgat aaattaggct tatatcatgg tcaaccccaa
     1201 atactttttt ctttaaagat gaaagatggg caaagtcaaa aagaattagc agataaaagg
     1261 aaagtaaaag catctacaac tacagttatg ataaagagga tggaaaaagc tggacttgtg
     1321 gaaagaaaac aagatgaaaa ggaccaaaga gtatctagga tttttttgac agacaaaggt
     1381 ttagaaatat gtaataaagt tgaagaattt aacaaggaat tggaaagaga gtttttttta
     1441 ggatttagtg aagaagaaaa aatagtactt agaagacttc taatgcaagt acgagataat
     1501 ttaaaagcag gatgtcataa gcatgaagat gaaaaatatt tttaaagttt aaaataatgt
     1561 ttttcaattt aatgttatta gactaattaa tattacagaa gggaagaaat gtatgtttaa
     1621 attaattaaa tatttaaaga aatcggcatt atcaatagta ataatagtct gtctattggt
     1681 aattcaagcg gtatgtgacc tttctttacc agaatacaca tccaatatag taaatgtagg
     1741 tatacaacaa ggtggagtag aaaactctgt tccatctgtg attagagaga gtgaattaaa
     1801 taaaattact ttatttatgg ataaaagtag taaggataaa gtactagata attatacttt
     1861 gctgaataaa aaggattatg ttaagtataa agataagtac ccaggtctaa aagatgaatc
     1921 tctttatgag ttaaatacta aagacaaaga cactatagat gatttaaatg ttatttttgg
     1981 taaagctatt ttaatagtat cagggcttga gggcgatagt aaagaggtaa aagctatgaa
     2041 agctcagtta atgagtaaac ttccaccaca agctactcaa agtggagatg ttgatatatt
     2101 taaattgtta tcagcaatgc caaaggaaca gttagataca ttgactaaag agatgagcaa
     2161 aggctttgaa agtatgccag agagtatgat aacacaaagc tctgtttcat atgtaaggtc
     2221 agaatatgag aaaataggta ttgatacaga aaaaactcaa aataattata tattatttac
     2281 tggtgctaaa atgcttggta tagcaatgat tagtatggta gctacaataa cagtaggatt
     2341 tttagcagca agagtagccg caagtgtagg tagaaattta agaagtggag tatttagaaa
     2401 agttatgtca ttttcaaata ctgaaatgaa tgaattttct acagcttcat taattactcg
     2461 tagtacaaat gatattcaac agatacaaat gttgatggtt atgttgctta gaatagtatt
     2521 ctatgcacct ataatggcta taggtggagt gataaaggtt ttaaacacaa atacttcaat
     2581 ggcctggatt atagcagtag cagtagttgc tatcttatca ttaattgtag tgttattctc
     2641 agtggttatg cctaagttta aactggttca aaagcttgtt gataagttaa acttagtaag
     2701 ccgtgaaata attactggta ttccagttat cagagctttt agtactgaaa aacatgaaga
     2761 agaaagattt gataaagcaa ataaaaattt aactaaaaca aatctttttg taaatagagt
     2821 tatgacatgt atgatgcctg ctatgatgct tataatgaac cttatcacag ttcttatagt
     2881 ttggagaggt gcatacagtg ttgattctgg agcaatgcaa gttggagata tgatggcatt
     2941 tatacaatat acaatgcaaa taataatgtc attcttaatg atatcaatgg tatctattat
     3001 gcttccaaga gcatccgttt cagctacacg tatagatgaa gtattagtgt cagatataag
     3061 cataaaagac ccagaaaaat cagaggcaca agagtttaag gaagataaaa agggtcttgt
     3121 tgaatttaaa aatgtttcgt tcatgtatcc agacgcagaa gaacctatat taacaaatat
     3181 atcttttaca gcaaagccag gagaaacaac tgcctttata ggaagtactg gtagtggtaa
     3241 gtcaactctt ataaatttaa ttcctcgttt ctttgatgtt actgaaggag aaatattact
     3301 tggtggagtt aatataaaaa atgtttctca acatgattta agggaaaaaa ttggatatgt
     3361 acctcaaaag ggagtattgt tttctggtac tatagaatcc aacttaaaat atggtagaaa
     3421 agacgcaaca gatgaagaaa tgagaacagc agctgaaata gctcaagcta cagaatttat
     3481 agattctaaa ccggaagctt ttaaaactga aatttctcaa ggtggaacaa atgtatctgg
     3541 aggtcaaaaa caaagacttt ctattgcaag agcaatagca aaaaatccag aagtttatat
     3601 atttgatgat agtttttcag cacttgactt aaaaactgat gcagctcttc gtaaggcttt
     3661 aaaatcaaaa actgctgaaa gtacagttct aatagttgca caaagaatta gtactatctt
     3721 aaatgcagaa cagataattg ttttaaatga gggcgaaata gttggaatag gaacacataa
     3781 agagcttcta aaaaattgcg aagtttatga gcaaatagct ttatcacaac tttcaaagga
     3841 ggagctagct aatgagtaga atgggaagag gtcctatggg aaaatctatg ggagcaggac
     3901 aaaaagcaaa tgactttaaa gggactatgc gaaaactaat tgcatattta tctaaattta
     3961 aaatatcaat aattctagta attgtatttg ctattggtag tgcgtcgttt tctatagtag
     4021 gtccaaaaat tttaggaaag gcaactacaa agatatttga agggctagtg agtaaagttt
     4081 ctggaggaaa cgtaggtata gattttaatg caattggaaa aatcttaacc tttttacttt
     4141 tcctttattt gataagtgca ctgttctctt ttatacaagg atttataatg agtggaattt
     4201 ctcaaaaagt atcctataat ttaagaaaag agatttcagc aaaattggat agattgccaa
     4261 tgaagtattt tgatactaag acgcatggtg aaatattatc gagaattacg aatgatatag
     4321 atactttaaa tcaaagttta aatcaaagta tgacacagct tataacatca gtaacaacta
     4381 tgataggtgt tttgataatg atgttatcta taagtggaat tatgacatta gtggcagttt
     4441 taatattacc aatatcaatg tttgtaattt caagaataat aaagaaatca caaaaatact
     4501 ttagatatca acaagaatat ttaggaaatg taaatggtca agttgaggaa acttacagtg
     4561 gccaaacaat agtaaaagca tttaatcgtg aggatgaagt aattgaagag tttgataaac
     4621 taaatgatag cctgtataat tcagcgtgga aatctcaatt tttatcaggt ataatgcaac
     4681 cacttatgat gtttattgga aacttgggat atgtaatggt atcaatctta ggaggttggc
     4741 ttgcaattaa gaaaacaatt gaggttggtg acatacagtc atttatacaa tatgtaagaa
     4801 actttacaca gccaatgact cagattgcac aggttgccaa tttattgcaa tcaacagcag
     4861 cagcttctga aagagtattt gagtttttag aagaggaaga agaagtccaa attgttgaaa
     4921 atgcagtttc aatagatggt ttagaaggta aaattgattt tgaaaatgtc aactttggat
     4981 ataacccaaa caagactata ataaatgatt tctcagtaaa tgttgaacct ggtcaaaaag
     5041 ttgctattgt tggacctaca ggagcaggta aaactacaat agttaaactg ttaatgagat
     5101 tttatgatgt taatagcggt tcaatactga ttgatggtca taatattaaa gattttaatc
     5161 gtagtgagct tagagaaatg tttggtatgg ttcttcaaga tacatggtta tttagtggtt
     5221 caattatgga aaatataaga tatggtaagt tgaatgctac agatgaagaa gttatagagg
     5281 ctgctaaatc tgcacatgtt catagattta ttaagacatt accagatgga tataagatga
     5341 aattaaatga agaagcaagt aatgtttctc aaggtcaaaa acaattattg actatagctc
     5401 gtgctatttt agctgatcct aaaattttaa tattagatga agctacaagt tctgtcgata
     5461 ctagaacaga agtattgatt caaaaagcta tggataatct tatggaaggt agaacaagtt
     5521 ttgttatagc ccacagatta tcaactatac gtgatgctga tatgattctt gtaatgaatg
     5581 aaggagatat agttgaacaa ggaaatcatg aggaacttct aaagaaaggc ggattctatg
     5641 ccaatcttta caattctcaa tttgaagaag atgaagcaat gtaacaaaaa actatcttag
     5701 catagacatg taattaataa gataaaataa atgagggtgc cttaaaatga actttttaat
     5761 tcataaggca ctcttttgtg tatgaaataa agtgtatttt tatcatttta acaatgaaaa
     5821 agaggattct ctatattttg agatagccac ataattttat gtctttacaa agtgtttatt
     5881 ttattataat atgtagtaag gaaaatgttg gaggtgatta tcaaaatgta tatttaattt
     5941 tattctttaa attttattat aaatagaatt taattttaat agttgatgat tatattgaag
     6001 tatatgtttt tattactttt attaatcatg caaataacta cttaaattta agaatagggt
     6061 taaatataaa atgataatta catataagtt aattaaacta atgtattttt aatatatatt
     6121 tagaatttta atccttctta tgatataagt agcttgtttt gtattactta gatttgtaag
     6181 gagttttttt attgaaaaaa ctgcataata tatttgggag gaggtgtaag aaagtgattt
     6241 tttatataag attgagaaaa taatgcacga ttatggttat tataatagta aataagaagt
     6301 gtcatttaag gataagataa aaagcaaaat tcttgatgaa tttaattata gagccataat
     6361 ctcgtgctat agattaaata aaaaatagca gataaggaga atatggatat ggcgaaaaaa
     6421 ggaataacag taggattaaa cataaataat aaatctgagg actttaatga actaatgatt
     6481 gaacttgaaa acttatgttc agcatgtgat attgatgttg tagggagtat aactcaaaat
     6541 gcaaagcagg ttaatagagc attttacatt gggacaggta aagttgagga aatattaaac
     6601 ttaataaaga aagaaaatat agagatagtt atattttaca atgaactttc tacatcacaa
     6661 ctaaaaaatc ttgaagaaaa gcttaattgt gaaattatag atagaacggc attgatactt
     6721 gatatatttg cacaaagggc aaaaactaga gaagctaaac ttcaagtaga agtagcaagt
     6781 ttaaaatata tgttaccaag acttataggt tcaaatgaaa atttaggacg tcaaagtggt
     6841 ggagttggta ctaaaaatag aggttctggt gagaaaaaat tagaacttga ccgtagaaga
     6901 atagaagaaa agataacatc tttaaatagg gagttggatg atttaaaatt ccaaagagaa
     6961 actcaaagaa gtatgagaag aaaatcaaat cttccaaatg tagctctagt cgggtataca
     7021 aatgctggta aatcttcaat aatgaataaa ctagtagata tatttaaaaa ctctgaagaa
     7081 aagaaagtgt ttgagaaaaa catgttattt gctacacttg aaacttctgt cagaaatata
     7141 gttcttgcaa ataacaaaga atttttatta tctgatactg ttggttttgt aagtaatcta
     7201 ccacatgact tagtaaaagc atttaggtca acattagaag aagcatgtga ggcagacgta
     7261 ctgttacatg ttattgatat ttcaaatcca agctataaaa gtcatattaa agtgacagaa
     7321 gatactttaa aacaaatagg tgcagatggt atacctatga tacatgtgta taataaaatt
     7381 gatttaatag atgtagacgt attggataga attttagata gtattgataa agaaggtata
     7441 tttgtttcag ttaaaaaaga tataaatata gataaaatga taaaatgtat ttgtgatagc
     7501 atatttaaag attatgtaag atgtaagttc ttaattccat atgataaagg tcatgtagtt
     7561 tcttatttta acgaaaatat gagcattata aatacagaat acagagaaga tggagctatt
     7621 ttagatgtag aatgtagcaa tatagaatat aataagtata aaaagtatgc tttagagtaa
     7681 attttgaaaa acttattata gcctaaaata tatttaattt ataatttatt ataaattgat
     7741 tgtaaatatg attttatgaa acggtatagc cataatgcta tgccgttttg ccatttataa
     7801 taaaaataaa tttattgaca taatagtaac taattactat aatataaagt aattagttac
     7861 tatttaaaat tatcaaaaaa ttaaaatcta agataaagag aagtgtataa taatggatgc
     7921 agaaacttta atgaaaaaat atatggtaga tgatgatagt agaaaacaag ctatatttgc
     7981 aagtatattt gtaatgcaaa ataaacttca aactacatgt gataaattag acccagaatt
     8041 aacaatgaaa caatggttac ttttagctat tgcggactct gtagatgaaa ctcttacatt
     8101 aaccaaactt ggagaattaa tggggtgctc aagacaaaat gtaaaaaaac tagctattgc
     8161 tttagaaaag aaaggtttta tacaaattga gcagaatgaa aaagattcaa gagctatctg
     8221 tcttgtgaca aaagatagag tgcaagagta ttctaaaaaa gtaagaggta tgcaggaaaa
     8281 agtattacag cttttatttg aagattttac agagaaagaa gtggaacagt tattttttgg
     8341 aattatgaaa ttaagtatag gaattgaaaa tgtgaaaaat tatgtagaaa ataatgacgt
     8401 tggagaataa gcaagtatca aatcaacttt gtatgacatc agagaggggg ataatttata
     8461 tgaaaaatgt agtagtgatt tataagagta agtatggttc aacaaaaaaa tatgctaaat
     8521 ggctttcaga attattgtct tgtgatattt ttgaaactaa gaatattaat atagaaaagg
     8581 ttatgaagta tgatacgatt attttaggag gaggtcttta tgcttgtaat atagcgggaa
     8641 tttctttctt aaaaaaaaat tataaagaat tgcagaaaaa aaatttagta gtatttggcg
     8701 taggagctgc tccatatgat gatgaagtaa taaagaaatt aagagaagta aattttaagg
     8761 atgaattaaa caaaattcct tgcttttatt gtcgtggggc atgggatgag acaaaaatgt
     8821 cttttataga ttatactctt tgtagttttt ttaaaaaatc tatagctaaa aaagaacgtc
     8881 aaggtcttaa accagcagaa gcacctttat tgtctggaga agcatttgat tggtgtaata
     8941 aagaaaattt aactccaata cttgattata taagagaact ttaagaggta tatatttata
     9001 attatttatt atctaaagtt agatttcata gaaacttact agacattatt tataaaataa
     9061 tattattaaa gatggataat ttaattgatt caataaggtt ataattttaa aaaatgttta
     9121 ttttaaaata aattatttta taagcttact tatacttaat aagg
//
LOCUS       DAEPKC010000127         8930 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.128, whole genome shotgun sequence.
ACCESSION   DAEPKC010000127 DAEPKC010000000
VERSION     DAEPKC010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8930)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8930)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8930
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.128"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            322..1752
                     /locus_tag="KR294_003345"
     CDS             322..1752
                     /locus_tag="KR294_003345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH0241395.1"
                     /translation="MSSQESKPKGNLISNFRDDMRDPKKRAIYTYSSSINLAYNFIGY
                     FVSTVTNIFLTDVAKLGVIMAGGMQIIQSFIKIAVAPITGTVFDKQPFKKGKYYPWLR
                     YAPAALALTYGIFFIVPLMKISPALLLPLMTALLLIASCAQQVVFTIIYAIYPVVAKT
                     PRDRVIGSTTTNIFKEVGKFLVGFSYPLLLVLFADVLGGEGMGYLGTYLFFAAGCLLV
                     FWFSSTEIIKSGAEEEVLQKEEKPKIKASEMAKALFTNVPLMMAFCLEFLICIRSIGL
                     GPLAPYYFKYVIEDERGLAVFLSIMPLVSVAFMFFAPVFIKICREQKLASIISFSICA
                     LCHLLVAWTPWGKTTLGVTMLLAIGGGFSNVVSIINLNFFAGSCDYGHWKSGKDLPGL
                     SMSLYPVAIQVGVLLATTIRTVLMNSMGYQADMVVTEAVKSGFINMISYSMAIPLIIA
                     VVIAILYPVSDKKLNQIREELNQRNA"
     gene            1855..2958
                     /locus_tag="KR294_003346"
     CDS             1855..2958
                     /locus_tag="KR294_003346"
                     /EC_number="2.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate transaminase"
                     /protein_id="HBH0241396.1"
                     /translation="MIEKLLRNTVKELHQYVPGEPIEKVKEKYGVKEIIKLASNENPL
                     GPSPKAIEAMIEMLKQGQLYPEPEANELRRKLAEKLDLKPENFIVANGADNVITLIGE
                     AFINRGDEVIYCNPTFPSYRTATIKNEGIPVEVPLTEDYKYDLQGILDKITDKTKLIC
                     VCNPNNPTGTIVDDKELEEFLKKVPENIITILDEAYIEFLTVPNYVDGLKYVRENYNV
                     IVTRTFSKIYGLAGLRVGYGIAKDEIIRTLFTVKEPFSANRVAISGATAALDDEEFIK
                     ETYELNRVGMAYFKEEFTKMGFDVVDSQSNFLYVDMKTDIPKLFEDLKKRGFVIRPSA
                     THARVSIGTMEENKKFVAVLKEILNIKGEPSIG"
     gene            2973..3209
                     /locus_tag="KR294_003347"
     CDS             2973..3209
                     /locus_tag="KR294_003347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBH0241397.1"
                     /translation="MKRGVDMNLKINAERCKSCEYCVISCKKGALKISSKINKEGYAH
                     VEVDESKCILCGICYQVCPDNVFEIIKEEACQEA"
     gene            3226..4275
                     /gene="vorB"
                     /locus_tag="KR294_003348"
     CDS             3226..4275
                     /gene="vorB"
                     /locus_tag="KR294_003348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate dehydrogenase subunit
                     VorB"
                     /protein_id="HBH0241398.1"
                     /translation="MKKMWKGNHAIAEAALRGGCEFYAGYPITPQTEVIEFLSHRMSE
                     LGRTFIQSENEMAAIYMVYGAYASGMRSMTSSSGPGISLKQEGISYLCANHYPCVIVN
                     VQRWGPGLGSLDSAQTDYLRDTRGGGNGDYHLIVYAPNSIQETVDLMYNSFDVAEKYR
                     VPVEILTEAALGQMMEPVEFPEFKKREGDLGWTYDGSNRDHAKVADNQKPTFCMEKRM
                     RITENEQQWEDYQVEDAEYVFVAFGIPSRTTMNAVRRLREQGEKVGIIRPITVWPFPY
                     KAFEKVSKDVKGFISVESTDTGQLVEDVALTSKKVCKENVPVYGLFSGNHIPKTLQVM
                     DTYSKIKSGEIKEVF"
     gene            4277..5017
                     /locus_tag="KR294_003349"
     CDS             4277..5017
                     /locus_tag="KR294_003349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate oxidoreductase"
                     /protein_id="HBH0241399.1"
                     /translation="MATEKLTPSVVSIPNKFCPGCGHGIVNRIIAEVIEEHGYEKNHV
                     LTLGVGCVCNMNFSWNGDKMQTAHGRASSTAIGVKVALPDTLVMTYQGDGDAYVIGLS
                     ETLNTAYRNHNVTVFVINNNNFAMTGGQMSWTTMPGQVTTTSVNGRDIKTTGSPLKVP
                     EMVANFFDVAYVARGSVHSPKEIINLKKYIKNAIEAQLNGEGYSLVEILAPCPTNWGV
                     SLEKSIKWMEEEIVPYYALGEFKQRDGE"
     gene            5020..5559
                     /locus_tag="KR294_003350"
     CDS             5020..5559
                     /locus_tag="KR294_003350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase family
                     protein"
                     /protein_id="HBH0241400.1"
                     /translation="MEKELVFAGFGGQGVLTLGLIVAESALELGKQVTWMPAYGPTMR
                     GGKAYSVVKFSDESIGGPDMEEIDVLVAMNKPSLDYINLVKEGGTVVINTSAIDENVT
                     LREDISVVKINCQELAQKVNNPKAANIVVLGALIAKTGLFEKELALKTMCDFFEEKGK
                     GKFNVQNEAAFMEGYNNAI"
     gene            5683..7782
                     /locus_tag="KR294_003351"
     CDS             5683..7782
                     /locus_tag="KR294_003351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate--CoA ligase family protein"
                     /protein_id="HBH0241401.1"
                     /translation="MSLEKLIRPKSIAIVGVTDKLGFGRSAALSIVKSKETDRVYYVN
                     PKREELFGRKCYKTIQEVPEVVDCVVVCTPRNVVPSVLKDSGELGTKAAVVYASGFAE
                     EGTEEGTDLENQLIEISNTYDMKILGPNCMGLLNCIDKVNLWAGGSKWDLDTKKPGIG
                     IVGQSGFITAEIVSSDYFNISYGFSTGNGNIVTLEDAVDFLVDDDYASVIAIYLEGLK
                     NPQKFIDALKRAAQKRKPVIILKSGRSEKGAISAASHTGNLAGSSKAFESIFEKYGVI
                     SVENLEQFMCLAQAFSVLDGNLPANSNFAAINFSGGENTICADLAEENGVELAEISSE
                     TKEEMKKYLPGFATPKNPLDATTALFHEKDMIVGLLHTFEKDDSVGFTMVGANIRDEE
                     NEMHETLCKAVSEAREQGLKKPVFAVPTLEGNRYLDYRTRLEDNQVPIMSSVGTTFTC
                     FNKMAKFIDYDYSKRTLEFKAVKKRESNNVVALSELDSKIEMKKYGVPVPGQGNAKSI
                     DELDEILKYIKYPVVLKINSSEILHKSDVGGVKIGIENRDEAVDAYNEILTNVKKAKP
                     DANIDGILVQEMVESGIEIIIGITNDDQFGPMLLVGLGGVFVEVFKDTTLYPLPINHD
                     EAIMMLKKLKSFKLLNGYRGSEPCDIDALADMMVKLGKYAYENKDEVKEIDLNPVFVY
                     PKGKGVCAVDALIVKYK"
     gene            complement(8049..8564)
                     /locus_tag="KR294_003352"
     CDS             complement(8049..8564)
                     /locus_tag="KR294_003352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferritin"
                     /protein_id="HBH0241402.1"
                     /translation="MISAKMEKLLNEQINHELYSAYLYLSMSSYLEAEGLKGFSNWFY
                     VQYKEETDHAMFFYKYLHNVGGKVQLDAIPMPDSDFTSAMDILERTLAHEKKVTALIN
                     NLAAVANSESDFRTSQFLLWFISEQAEEETNCEDNIKRVKLAGEGGLFFVDQEFANRT
                     YAAPTNPPVTI"
     gene            complement(8656..>8930)
                     /locus_tag="KR294_003353"
     CDS             complement(8656..>8930)
                     /locus_tag="KR294_003353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HBH0241403.1"
                     /translation="LIDEFCTYVSYALVNTLTLIDCSSIIIGYDFNIPGTFIENTLLK
                     KLTASASFSKYKKISVRHSNFGANAPLIGSIAIVSYNFFNGSINFY"
BASE COUNT         3415 a         1073 c         1708 g         2734 t
ORIGIN      
        1 aataaaatta taaaaaatta aaatcactag aaatatgata aaataattta aaatacgcat
       61 ttcaatgaca tttcaaaaca ataaaataat aaaaaacaaa cctaaattaa gtctaaatag
      121 ctttttagtt aattttagta gtaaaaaata aaacttaaaa agtgtttgac aattatgaat
      181 tttgagaata taattaaatt aaaattatac acatataaaa atatactcct gaatcaagaa
      241 tgagatattt aagattcaaa atatatatta ttatacgtga ataataaaaa agtaagaaaa
      301 ttttataagg gaggggtaga tgtgagtagt caagaaagca aaccaaaagg aaatcttata
      361 tcaaatttta gagatgatat gagagaccct aagaaaagag caatatacac atattcaagt
      421 tctataaact tagcgtacaa ttttataggt tactttgtat caactgttac aaatattttt
      481 ttaactgatg tggcaaaact tggtgtaatt atggcaggtg gtatgcaaat tatacaatct
      541 ttcataaaaa ttgctgtagc tcctataaca ggtacagtat ttgacaaaca accattcaaa
      601 aaaggaaagt attatccatg gcttagatat gcaccagcag cgttagcatt aacatatgga
      661 atatttttca tagttccatt aatgaaaata agtccagcat tacttttacc tttgatgaca
      721 gctttattat taatagcatc ttgtgctcag caagtagttt tcactataat ttatgctatt
      781 taccctgtag ttgctaagac acctagagac cgagttatag gctcaactac tacgaatata
      841 tttaaagaag ttggtaaatt cttagtaggt ttttcatatc cgttattatt agttttattt
      901 gcagatgtat taggtggaga aggaatgggt tatttaggta cctacttatt ctttgcagca
      961 ggatgccttt tagtattttg gttttcttca acagagataa taaaatctgg agcagaagaa
     1021 gaagttcttc aaaaagaaga gaagccaaag attaaagcaa gtgaaatggc aaaagcttta
     1081 ttcactaatg taccacttat gatggcattt tgtttagaat ttcttatatg tataagatct
     1141 ataggattag gacctttggc tccatattat tttaaatatg taatagaaga tgaacgtgga
     1201 ttagcagtat ttttatcaat catgcctttg gtaagtgtag cattcatgtt tttcgcacca
     1261 gtgtttataa aaatctgtag agagcaaaaa ctagcttcaa taatttcttt ttctatatgt
     1321 gcactatgcc acttattggt tgcatggact ccttggggga aaactacttt aggagtaact
     1381 atgttgctgg caattggtgg aggtttttca aatgtagtat caataataaa tcttaatttc
     1441 tttgccggtt cttgtgatta tgggcattgg aaatcaggaa aagacttacc tggcttaagt
     1501 atgtcactat atccagttgc aatacaagta ggagtattac ttgcaactac tataagaaca
     1561 gttttaatga actcaatggg atatcaagct gatatggtag tcacagaagc agttaaatca
     1621 ggttttataa atatgatttc ttattctatg gcaatacctt taataatagc tgttgttata
     1681 gcaatactat atccagtaag tgacaagaaa ttaaaccaaa taagagaaga gttaaatcaa
     1741 agaaatgctt agttaaaaga aagttaagta gatggttaat ttaagctatt aaagtaagta
     1801 gacgcaatag cgtttatata aatgaaaata catatacaga gggggctttt aaaaatgata
     1861 gaaaaattat tgagaaatac cgtaaaagaa ttacatcaat atgttccagg tgaaccaata
     1921 gaaaaagtta aggaaaaata tggtgtaaaa gaaataataa aattagcttc aaatgaaaat
     1981 cctctaggac catcaccaaa agcaatagaa gctatgattg aaatgttaaa acaaggtcaa
     2041 ctttatccag agccagaagc taacgaactt agaagaaaat tagctgaaaa gctagattta
     2101 aaaccagaaa attttattgt tgctaatggt gcagataacg ttatcactct aataggtgag
     2161 gcttttataa atagaggaga tgaagttata tattgtaacc caacatttcc atcatataga
     2221 actgcaacta taaaaaatga agggatacca gtagaagtac ctttaacaga agattataag
     2281 tatgatttac aaggtatatt agataagatt acagataaaa caaaattaat atgtgtatgt
     2341 aaccctaata atccaacagg aacaattgtg gatgataaag agttagaaga atttttaaag
     2401 aaagtccctg aaaatattat aactatattg gatgaagcat atatagaatt tttaacagtt
     2461 cctaattatg tggatggact taagtatgta agggaaaatt ataacgttat agtaacaaga
     2521 actttctcta aaatatatgg tcttgcaggg cttagagtag gatatggtat tgctaaagat
     2581 gagataataa gaactttatt tacagtaaaa gagcctttct ctgcaaatcg tgttgctata
     2641 agtggagcaa cagcagcact tgatgatgaa gagtttataa aagaaacata tgaattaaat
     2701 agagttggaa tggcttactt taaagaagag tttacaaaaa tgggatttga tgttgtagat
     2761 tcacaatcaa atttccttta tgtagatatg aaaacagata tacctaagtt atttgaagac
     2821 ttgaaaaaaa gagggtttgt aataagacca agtgctacac atgcacgtgt aagtattgga
     2881 actatggaag aaaataagaa atttgtagca gttttaaagg aaatattaaa tattaaagga
     2941 gagccaagta ttggataata gatagaaata ttatgaaacg gggtgtagat atgaacttaa
     3001 aaataaacgc agagagatgt aaaagttgtg aatactgcgt tatatcttgt aaaaaaggag
     3061 cattaaaaat atcaagtaag ataaacaaag aaggttatgc tcatgtagaa gttgatgaga
     3121 gtaaatgcat actttgtgga atttgctatc aggtgtgtcc agataatgtt tttgaaataa
     3181 ttaaagaaga agcatgtcaa gaggcttaga aggagttggg ataatatgaa aaagatgtgg
     3241 aaggggaacc acgccattgc agaagcagcc ctaagaggag gttgtgaatt ttatgcagga
     3301 tatccaatta caccacaaac agaggtaatt gaatttttat cacatagaat gtctgaactt
     3361 ggaagaactt ttatacagtc cgaaaatgag atggctgcta tatatatggt atatggagca
     3421 tatgcaagtg gaatgaggtc tatgacgagt tcttcaggac caggaatatc tttaaaacaa
     3481 gaagggattt cttacttatg tgcaaatcat tacccttgtg taatcgtaaa tgtacagaga
     3541 tgggggcctg gtcttggctc attggactca gcacagacag actatctaag agatactaga
     3601 gggggaggaa atggagatta tcatttgata gtttatgcac caaacagtat tcaagagact
     3661 gtagatttga tgtataactc atttgatgta gcggagaagt acagagtgcc tgtcgaaatt
     3721 ttgacagaag cagctttagg tcaaatgatg gaaccagtag aatttccaga gtttaagaag
     3781 agagaaggag atttaggctg gacttatgat ggaagtaata gagaccatgc aaaggttgca
     3841 gataaccaaa agccaacttt ttgtatggag aaacgtatga gaataactga aaatgaacaa
     3901 caatgggaag attatcaagt agaagatgca gaatatgtgt ttgtagcgtt cggtatacca
     3961 tcaagaacaa ctatgaatgc tgttagaaga cttagagaac aaggtgaaaa agttggaata
     4021 ataagaccaa taacagtatg gcctttccca tataaagcat ttgaaaaggt aagtaaagat
     4081 gtaaaaggat ttatctcagt agaatcaaca gacacaggtc aattagtaga agatgttgct
     4141 ttaacctcaa agaaagtatg taaagaaaat gtacctgtgt atggtttatt tagtggaaat
     4201 catataccaa aaacattgca agtaatggac acttatagca aaataaaatc tggcgaaatc
     4261 aaggaggtgt tctaatatgg ctacagaaaa attaacacct agcgttgttt caataccaaa
     4321 caagttttgc ccaggttgtg gtcatggaat agtaaatcgt ataatagcag aggtaataga
     4381 agaacatgga tatgaaaaaa atcatgtatt aacattagga gttggttgtg tctgcaatat
     4441 gaattttagc tggaatggtg ataagatgca aactgcacat ggtagagctt catctacagc
     4501 tataggagtt aaagtagcac ttccagatac attagtaatg acttaccaag gtgatggaga
     4561 tgcttatgtt ataggtcttt ctgaaacttt aaatacagca tatagaaatc ataatgtgac
     4621 tgtatttgta ataaacaata ataattttgc aatgactggt ggacaaatgt catggaccac
     4681 tatgccgggt caagtcacaa caacaagtgt aaatggaaga gatataaaga ctactggtag
     4741 tccactgaaa gttcctgaga tggtggcaaa cttctttgat gtagcatatg tagcaagagg
     4801 ttcagttcat agcccaaagg aaataattaa tctaaaaaaa tatataaaaa atgcaataga
     4861 agctcaatta aatggagagg gatattcctt agttgaaata ttagcacctt gtccaactaa
     4921 ctggggtgta tcactagaga aatctatcaa atggatggaa gaagaaatag tgccatatta
     4981 tgctcttggc gaatttaagc aaagggatgg tgaatagtta tggaaaaaga gctagtattt
     5041 gcagggtttg gtggtcaagg agttttaact cttggtctga ttgtagctga gtcagcactt
     5101 gaattgggga aacaagtaac ttggatgcct gcatatggtc caactatgag aggtggaaaa
     5161 gcctatagtg tagtaaagtt ttctgatgag agtataggtg ggcctgatat ggaagaaata
     5221 gatgttttag tagcaatgaa taaaccatct ttagattata taaatttagt taaagaaggt
     5281 ggaacagtag ttattaatac atctgcaata gatgagaatg taacattaag agaagatata
     5341 agtgtagtta aaataaattg tcaggaatta gctcaaaaag taaacaatcc aaaagcagca
     5401 aatatagtag tacttggagc attaattgct aaaacagggt tatttgaaaa agaattagct
     5461 ttaaaaacta tgtgtgattt ctttgaggaa aaaggaaaag gaaagtttaa tgttcaaaat
     5521 gaagcagcat tcatggaagg ctataataac gccatttgat aaattaccct tatcttaagt
     5581 gatttatctc aagatttaat aatctttagt gccaagagaa acttcatctt gagataaaat
     5641 tcacttaaaa tcacaactat aaacatatag gagcgtgaat ttatgagttt ggaaaaactt
     5701 attagaccaa aaagtattgc tatagtagga gtgactgata aacttggttt tggaagaagt
     5761 gcagcactta gtatagtaaa aagtaaggaa acagatagag tatattatgt taatcccaaa
     5821 agagaagaat tgtttgggag aaaatgttat aagacgatac aagaagttcc agaagtagta
     5881 gactgtgtag tagtatgtac acctagaaat gtagttccat ctgtattaaa agattctgga
     5941 gagttaggaa caaaggcagc agtggtatat gctagtggat ttgcagagga aggtacagag
     6001 gaaggtacag atttagaaaa tcaacttata gaaatatcaa atacatacga tatgaaaata
     6061 ttgggtccaa actgcatggg gttgctaaat tgtatagata aggttaatct atgggcagga
     6121 ggttctaaat gggatttaga tactaaaaaa cctggtatag gaattgtagg tcaaagtgga
     6181 tttataactg ctgaaattgt ttcaagtgat tattttaata tatcttatgg tttttcaaca
     6241 ggaaatggaa atatagttac actagaagat gcagtagatt tccttgtaga tgatgattat
     6301 gcatcagtaa tagcaattta ccttgaaggt ttaaaaaatc ctcaaaaatt tatagatgct
     6361 ttaaaaaggg cagcacaaaa aagaaagcca gtaataatat tgaaatcagg aaggtcagaa
     6421 aaaggtgcta tttctgctgc ttctcataca ggaaatttag ctggttcgag taaagctttt
     6481 gaaagtattt ttgaaaaata tggagtaatt tctgtggaaa atttagaaca gtttatgtgt
     6541 ttagcacaag cttttagtgt tttagatggt aatttacctg caaattctaa ttttgcagca
     6601 ataaacttct caggaggaga aaatactatt tgtgcagatt tagcagaaga aaatggtgta
     6661 gaacttgcag aaatatcttc tgaaactaaa gaagaaatga aaaaatatct tccaggattt
     6721 gcaacaccta aaaatccact agatgctaca acagcattat tccatgaaaa ggatatgata
     6781 gtaggtttat tacatacctt tgaaaaggat gatagtgttg gatttactat ggtaggtgca
     6841 aatataagag atgaagaaaa tgaaatgcat gaaacccttt gtaaagctgt aagtgaagct
     6901 agagaacaag gattgaaaaa acctgtgttt gcagttccta cacttgaagg aaatagatat
     6961 ttagattata ggactagatt agaagataat caagtgccta taatgtcatc agttggaact
     7021 acatttactt gttttaataa aatggctaag tttatagatt atgattattc aaaaagaact
     7081 ttagaattta aagctgttaa gaaaagagag tcaaataatg tagtagcatt atcagaatta
     7141 gatagtaaga ttgagatgaa aaaatatgga gtaccagttc caggacaagg taatgcaaaa
     7201 agtattgatg aattagatga aatcttaaaa tatattaagt atcctgttgt tttaaaaata
     7261 aattcttctg aaatattgca caaatctgat gttggaggag ttaaaatagg aattgagaat
     7321 agagatgagg cagtagatgc atataatgag attttaacta atgtaaaaaa agcaaaacca
     7381 gatgctaata ttgatggtat attagttcaa gaaatggtag aaagtggtat agaaattatt
     7441 attggtataa ctaatgatga ccaatttgga ccaatgttat tagtcggttt aggaggagta
     7501 tttgtagagg tatttaaaga tactacatta tatccattac ctataaatca tgatgaagct
     7561 attatgatgc ttaaaaaact aaaatcattt aagcttttaa atggctatag aggaagtgag
     7621 ccttgtgata ttgatgctct tgcagatatg atggtcaagt taggaaaata tgcttatgaa
     7681 aataaggatg aagtcaagga aatagactta aatccagtgt ttgtatatcc taaaggaaaa
     7741 ggcgtatgtg cagtagatgc cttaatagtt aaatataaat agtttataag ttttggtatt
     7801 caaccataat taaagcaccg actgaaaatc acattttgta agttagatag tgtgattttc
     7861 agtcacccca aatttaattt aaaaatattt taaaatgaaa gtatagtttt aagtttaatt
     7921 gtgaaatagc actgtataaa caataaaata ctacgtataa aacgaataat aaaaggtgtt
     7981 ttaatgataa gaatcaatct tgattttcat taaaacacct tctttattat attaaaaatt
     8041 tttaaacgtt atattgtcac aggtgggttt gttggagctg catatgtacg attagcaaat
     8101 tcttggtcaa caaagaatag accaccctct ccagcaagtt taacacgttt tatattgtct
     8161 tcacaatttg tttcttcttc tgcttgttca gatataaacc aaagtaagaa ttgagaagtt
     8221 ctaaagtctg attcagagtt tgctacagct gctaagttgt ttattaaagc tgtaaccttt
     8281 ttttcatgag ctaacgtacg ctcaagaata tccattgcag aagtaaagtc tgaatctggc
     8341 attgggatag catcaagctg aacctttcct cctacattat gtaagtattt gtaaaaaaac
     8401 atagcgtggt ctgtctcttc tttatattga acataaaacc aattagaaaa tcctttaagt
     8461 ccttctgctt caaggtaaga agacatagaa agataaagat acgcagaata taattcatgg
     8521 ttaatctgct cattaagtaa tttttccatt ttagctgaaa tcatttttat acctccaaat
     8581 tttaaatgct cttataaaat ataataatat taaatggaaa aatattcaat aaaagtgttt
     8641 aaatatttta catatttaat aaaaatttat actaccatta aaaaaattat aacttacaat
     8701 ggctatagag ccaattaatg gtgcatttgc tccaaaattt gaatgcctta cacttatttt
     8761 tttatattta gaaaaacttg ctgaagcagt caattttttt aataatgtat tttctataaa
     8821 tgtaccaggt atattaaagt catagcctat tattatagaa ctacaatcaa tcaatgtaag
     8881 tgtattaact aatgcatatg atacgtatgt acaaaattca tcaatcaaaa
//
LOCUS       DAEPKC010000128         8816 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.129, whole genome shotgun sequence.
ACCESSION   DAEPKC010000128 DAEPKC010000000
VERSION     DAEPKC010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8816)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8816)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8816
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.129"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            39..1238
                     /locus_tag="KR294_003354"
     CDS             39..1238
                     /locus_tag="KR294_003354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241404.1"
                     /translation="MKLKSKISILIIFLTLAIYFSIGLLNNEDNLKIKTIKGDSNELD
                     HININFGYALNGYINSYYTINGSNKTKKTELIKLQKDSKNTNNLIDVSSGSDLIAHVG
                     FEMNEESKDINFVIDEKKEDLEKGVFPSEDSDKEIEYEKLDMNNFTRTRYKVDKSTDD
                     YYAKILSSKRYKKYLYVSVLYATSDSSENNKEYSSTIDIIKINPENKKIKTIKSINLS
                     NYFSEKYQNIENIGVSYASKYEDKMYILVNVLNTNIGDNSNSKFHLLEYNLEENKESI
                     MELKTDSKMALAKAKLEANKLYMVMSNDYDNSSITELNLLTYNILDKSLDEDKYVLDN
                     REKRGIRSIEIDSNKIVAYTSRLNSILSWDDKFMLYIINKNSKEIVYEGELQFNSSNS
                     MLEFEIK"
     gene            1247..2059
                     /locus_tag="KR294_003355"
     CDS             1247..2059
                     /locus_tag="KR294_003355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241405.1"
                     /translation="MKDLIRLFEFELKRNIKNYIFIIICCCSFVILNIVKNLNDYNYI
                     IENAVKSEQLTKIGNTIETVNVTGFSSFRNIMGSTELWFMFGIIACICYAFFIWYRDF
                     NGRSKSIYTLIMLPKNRINIYISKLLNILFLVYSYTVVLTISLFIASKLLPRHMLGNV
                     TNYGFVQETIYELKMLLPYSFEILFVEYIFLLIGFVSVVFTSILINKSIYKVSTLISF
                     LFLVIEILVFIISIEFIIPYEYSDVFTVLYSSINIFVCSLISNKLLKQKIDF"
     gene            2070..3338
                     /locus_tag="KR294_003356"
     CDS             2070..3338
                     /locus_tag="KR294_003356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241406.1"
                     /translation="MKAKNIGKYTICFIIVCFLMITMTLILSYFNKDKLSVKTLKGNV
                     KDIGRVSVVYTPNISKFSYEEVIISKNGVRNNTNPKSRIRNDYLNIDKKYSDFVNDKG
                     KEFIYKDDLNIGEAYTSVKSDLVQGMNALNDCIKVSNKNLKSGVEENFDINLNKSDFK
                     ENSWKTLFNKIYKGNLYMVISETNISGSKVNNICILKIDIKNKSYKLLNRFNLGLQNG
                     EQQNINEIKFSIGSKLYLEIVNNKSKNGYIEGHDSYSNFIIYDIEDNTFNISNKFMDN
                     LNKEKNANPKEIGLLSKTKLDYMVKNNKLNLIVTDMSNSITNLVYDINSNEIKLEDYE
                     ILDLKVDYNEASSGVRKVKLLDDKIYSISGIKNSISGELKGFKGIVDVVGTKPVKFQV
                     FDMKLKKNIYEAELINGDISLQEKLFFVAN"
     gene            3704..4885
                     /locus_tag="KR294_003357"
     CDS             3704..4885
                     /locus_tag="KR294_003357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HBH0241407.1"
                     /translation="MNKKYIKAGNLIDGTGNSIMQNKGIIIDGDTIVEIEDIRDDLNG
                     YDVYDYLDKTVMPGIMNCHVHLTMEPVGNPKIYYDNVSDVELVVNTIKQLDAYLDSGV
                     TYIRSLGCPKYVDVQLKNLIDKGSIDGPGIVTSGPVICMTGGHGYYFGIESDGVDECR
                     KSARTVLKNGVDCVKIMATGGVTTDGVEPGSPQLTLEEMKAAVDEAIKAGKITATHAQ
                     GRTGIKNAVLAGITSIEHGVYLDDEIIDLMLERGTYLVPTVAAPYFILNAGKESGITE
                     ATLRKCEIVAIPHKESFLKAYKKGIKIAVGSDAGTSYNEHGKTYYEMKLMSDYGMDNM
                     DIIVAATKTASELLRIDKNYGTLEKGKKADVIVVNGNPVENIDVLADVLAVFKLGKKV
                     R"
     gene            complement(5027..5944)
                     /locus_tag="KR294_003358"
     CDS             complement(5027..5944)
                     /locus_tag="KR294_003358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241408.1"
                     /translation="MENNKCREDFRFTQEYEEDYPNTNERYYENYQVADRYYNYPNKY
                     KEPKIKQCCCKKSMREALELLRYDALRPFVNFNQFAFISDFFIVGANLVGIDLSAPPK
                     DNLSGLDGTFERFSACNCDLIDIAGRVSYPIPVPLTLEGLINTIGTIPGVAELIALID
                     AVIPPTIDLGAILDAILAAIIDFILAASTPLANVDLASLCNLKAVAFDITPADYEDFI
                     ASLGYYLDKKHYKECNCNCDCDDCCCNKGILDNLYMSNINNQVTVVAGSLVLTGVEVL
                     GKKNDVIVLGNSNDSRIYFVCVDSIDYIA"
     gene            6197..6991
                     /locus_tag="KR294_003359"
     CDS             6197..6991
                     /locus_tag="KR294_003359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0241409.1"
                     /translation="MIEVDKLCKSFTRVVKDDKNKSSIRKLKKVKTKKEEFFAVNNVS
                     FKVMEGEIVGILGPNGAGKTTLLRMLGGILTPTSGSINISGYDYSIDRNSAKKEIGYL
                     SGNTKLYGRLSPRELLTTFASLYEMSKEDIEESIENIVKIMDMSEFIDNRIENLSTGQ
                     TQRTSIARCLIHSPKVYIFDEPTLGLDVLSSASIIDFMKNEKLRGKTVLYSTHYMEEA
                     ETLCDKIFMIHNGKIIASGTPQSLKEESGVNNLRDVFIKLARKEDI"
     gene            6992..>8816
                     /locus_tag="KR294_003360"
     CDS             6992..>8816
                     /locus_tag="KR294_003360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBH0241410.1"
                     /translation="MRSKIVKYIFKKEMLDILRDKKTLFMMIVVPLLLYPLLMLLMIQ
                     VMNMSASSMNSKDINIAFNNKPNKVLVSMIEDDNLEKDTKNTSNDKGKIRVLDVDNYK
                     KSLEENKIDAYIKMEEKKSSINYQIYINSSQENSSNALKRIETVLDKYKRFTIEKTLS
                     EKGLDVQATLEPITYSTVDVAKTEEVAGYFLGQILPFILIIGVLLGSIYPAIDVMAGE
                     KERGTLETLFTLPISNLELVMGKYMAVSLSAIVTAILNILSMGLTMAFILVSGGISSQ
                     FGFGNFNYGDLVLPIITTLICICLFSMVVSAISMCVCSLAKSFKDAQNYITPLMLIIM
                     IPSYVSMIPNIVLDRVTAVIPVVNISLLIKSVLSFKSDLNLIALVLASNVAFVILAII
                     LLSKMFNSEEILFGNSKSFSFLEKRSNIKKGSIPTVSDGVILYAVGLVLLIYVGSLVQ
                     IKFGMAGIIMTQFMIISLPLLFAYYIKADFKEVFSLKVPKLKHVFGSIVLWIGGYILI
                     MIITQLILFLFPQNMEVAESLNKALFIKDSVLLNLLAIALLPALCEEMFFRGFIFSSF
                     SKSKDKNKSIKLAIICSGVLFGIMHMDFIRIIPTSILGIIFA"
BASE COUNT         3537 a          879 c         1405 g         2995 t
ORIGIN      
        1 ctaattaaaa agaaagtatc tctttaagga ggggtggtat gaaattaaaa tctaaaatat
       61 ctatacttat tatatttttg actttagcaa tatattttag tataggttta ttaaataatg
      121 aagataattt aaagataaaa actataaaag gtgactctaa tgaattagac catataaaca
      181 taaattttgg atatgctttg aatggatata taaattcata ttatacaata aatggaagca
      241 acaaaactaa aaagactgaa ttaataaaac tacaaaagga tagtaagaac acaaataatt
      301 taattgatgt atctagtggt tcagatttaa ttgctcatgt tggatttgaa atgaatgagg
      361 agtcaaaaga tataaacttt gtgatagatg agaaaaaaga agatttagaa aaaggtgtat
      421 ttccatcaga agatagtgat aaagaaattg aatatgaaaa attagatatg aataatttta
      481 caaggacaag atataaagta gataaaagta cagatgatta ttatgcaaag atactatcat
      541 caaaaagata taaaaaatac ttatatgtat ctgtacttta tgctacaagt gattcatcag
      601 aaaataacaa agaatattca agtactatag atataataaa aattaatcca gaaaataaaa
      661 aaatcaagac tataaaaagt ataaatttaa gtaattattt ttccgaaaaa taccaaaaca
      721 tagagaacat aggtgtaagt tatgctagca aatatgagga taagatgtat attttagtaa
      781 atgtactaaa tacaaacata ggtgataata gtaattctaa atttcattta cttgagtata
      841 atcttgaaga aaataaggaa agcataatgg aattaaaaac tgatagcaaa atggctttag
      901 caaaagcaaa gttagaagct aataaattat atatggtaat gtcgaatgat tatgataata
      961 gttcaattac agagttaaat ttacttacct ataatatatt agataaaagc ttagatgaag
     1021 ataaatatgt tttagataat agagaaaaaa gaggaattag aagtattgaa attgattcaa
     1081 ataaaatcgt tgcatataca tcaaggctaa actctatatt atcttgggat gataaattta
     1141 tgctatatat aataaataaa aattctaagg aaattgtata tgaaggagaa ttacaattta
     1201 acagttcaaa tagtatgtta gaatttgaaa taaagtaggt gagttgatga aagatttaat
     1261 aagattattc gaatttgaat taaaaagaaa tataaagaat tatatattta taataatttg
     1321 ttgttgttct tttgtaattt taaacatagt aaaaaattta aatgactata attacataat
     1381 agaaaatgca gttaaaagtg aacagttaac aaaaatcgga aatacgatag aaacggtaaa
     1441 tgttacaggt ttctcaagct ttagaaatat aatgggttct acagaattgt ggtttatgtt
     1501 tggtataatt gcatgtattt gctatgcttt ttttatttgg tatagagact ttaatggtag
     1561 aagtaaatct atatatacac ttataatgct acctaaaaat agaatcaata tttatatatc
     1621 taaattatta aatatattat ttctagtgta tagctataca gtagtactta caatatcttt
     1681 gtttattgca agtaagttgt tacctagaca tatgcttggt aatgtcacaa actatggttt
     1741 tgtacaagaa acaatatatg agttaaaaat gttacttcca tatagctttg aaatactatt
     1801 tgtagagtat atatttttat tgataggatt tgtatctgta gtatttacat caattcttat
     1861 aaataaatct atttataaag taagcacttt aataagtttt ctatttttag ttatagaaat
     1921 tttagtgttt ataatttcta tagaatttat tataccttac gaatacagtg atgtatttac
     1981 tgttctatat tcaagtataa acatatttgt atgtagtctt atatctaata aacttttgaa
     2041 gcaaaagatt gacttttagg agggatatta tgaaagcaaa aaatatagga aaatatacaa
     2101 tatgttttat aatagtatgt tttttaatga ttactatgac cttaatattg agttatttta
     2161 ataaggataa actatctgta aaaactttaa aaggcaatgt aaaagatata gggagagtaa
     2221 gtgtagtata tacacctaat ataagcaaat tttcttatga ggaggtaatt ataagtaaaa
     2281 atggagtaag aaataataca aacccaaaat caagaattag aaatgattat ttaaatattg
     2341 acaaaaaata cagtgacttt gttaatgata aaggaaaaga atttatatat aaagatgatt
     2401 tgaatatagg agaagcgtat acctctgtta agtctgattt agtacaagga atgaatgctt
     2461 taaatgattg tataaaggtt tcaaataaaa atttaaaaag tggggtagaa gaaaattttg
     2521 atattaattt aaataagtct gattttaaag aaaatagttg gaaaacctta tttaacaaaa
     2581 tatataaagg taatttatat atggtaatta gtgaaactaa tatttcaggt tctaaagtca
     2641 ataatatttg tatattaaag atagatataa aaaataagtc ttataaatta ttaaatagat
     2701 ttaatttagg attacagaat ggagaacaac aaaatatcaa tgaaattaaa ttttctattg
     2761 gaagtaaatt atacttagaa atagtaaata ataaaagtaa aaatggatat attgaaggac
     2821 atgatagtta ctctaacttt attatatatg atatagaaga taacactttt aatataagta
     2881 ataaatttat ggataatcta aacaaagaaa agaatgcaaa tccaaaggag attggcttat
     2941 taagtaaaac taagctagat tatatggtaa aaaacaataa attgaatctt atagttacgg
     3001 atatgagtaa ttccataact aatcttgttt atgatattaa ttctaatgag attaaattag
     3061 aagattatga gatacttgat ttaaaagtag attataatga agcatcatct ggagttagga
     3121 aagttaagct actggatgat aagatatatt ctatttcagg tattaagaac agtatatcag
     3181 gagaattaaa aggatttaaa gggattgttg atgtagtcgg aactaagcca gtaaaatttc
     3241 aagtatttga tatgaaactt aaaaagaata tttatgaagc tgagctaata aatggagata
     3301 taagtttaca agaaaagtta ttttttgttg caaattaagt gttagaatta attttagaac
     3361 tttaaacttt tatatgtatc acagataagt ataagtaagg gagtgtctca aaataaactt
     3421 tttagctcat gagacacttt ttttatatga aatcaaatat attttcattg tttagattta
     3481 ttttgataat gaaaaaaaga ttatctttat tttaagaaag acatttattt ataattatat
     3541 acaaaaatat tttttaatgt ttttgtgtat aattataaca atttaattta tattaatgca
     3601 cttaaatttg aaatagaatg cttatagtgg taaaattaat tattagaata ttagaaataa
     3661 taaataaata atacattgta cttaaaaggg ggagaaattt aagatgaaca aaaaatatat
     3721 taaagcaggg aatttaattg atggaaccgg aaatagtatt atgcaaaata agggtataat
     3781 tattgatgga gatactatag ttgaaattga agatataaga gatgatttaa atggatatga
     3841 tgtgtacgat tacttagata aaactgttat gccaggcatt atgaattgtc atgttcactt
     3901 gacaatggag ccagttggaa atccaaagat atattatgat aatgtatcag atgtagagct
     3961 tgtagtaaat acgataaaac aacttgatgc ttatttggat tcaggagtaa catatattag
     4021 aagcttaggt tgtcccaaat atgtggatgt acaacttaaa aatcttatag acaaagggtc
     4081 tatagatggt cctggtatag ttacttcagg tccagttata tgtatgacag gagggcatgg
     4141 atattatttt ggtattgaaa gtgatggagt ggatgaatgt agaaaatcag ccagaacagt
     4201 tttaaaaaat ggagtagatt gtgtaaagat aatggcaact ggaggtgtaa caactgatgg
     4261 agttgagcca gggtcaccac aattaacttt ggaggaaatg aaggctgctg tagatgaagc
     4321 tataaaagca ggtaaaataa ctgccacaca tgcacaagga agaactggta taaaaaatgc
     4381 agtgcttgca ggaattactt ctatagaaca tggtgtttat ttagatgatg aaataattga
     4441 tttgatgctt gaaagaggaa cttacttagt tccaactgtg gctgcaccat attttattct
     4501 aaatgcagga aaagaaagtg gaataactga agctactctt agaaagtgtg agattgttgc
     4561 cattccacat aaagagtcat tcctaaaagc atataaaaaa ggaattaaaa ttgcagttgg
     4621 ttctgatgca ggaacttctt ataatgaaca tggaaaaaca tattatgaaa tgaaactaat
     4681 gtcagattat ggtatggata atatggatat aatagttgct gctacaaaaa cagcatctga
     4741 acttttaaga attgataaaa attatggaac tctagaaaaa ggaaagaaag cagatgttat
     4801 agttgtaaat ggaaatccag tagagaatat agacgtactt gcagatgtgt tagcagtatt
     4861 taaacttggt aaaaaagtta gataaatagt ataaaaataa aaaagagtgt ctaaagaaat
     4921 ttttaaataa ttatagacac tcttttttat tagtaataat taaatctttt atactttaga
     4981 aaatagattc tattttatat ttagatataa ctctttaaaa tcattcttat gcaatataat
     5041 ctatagaatc tacacataca aagtatattc ttgaatcatt agaatttcca agtactataa
     5101 catcattttt cttacctaga acttcaacac cagttagaac caaactacca gctactacag
     5161 taacttgatt atttatattt gacatataaa gattatctag gataccttta ttacaacagc
     5221 aatcatcaca atcgcagttg caattacatt ctttgtaatg ttttttatca agatagtaac
     5281 ctaaagatgc tatgaaatct tcataatctg caggtgtaat atcaaatgca acagctttaa
     5341 gattacacaa tgatgctaaa tctacgtttg ctaatggagt agatgcagca agtataaaat
     5401 caattatagc agcaagtatt gcatctaata tagccccaag gtctatcgta ggaggaataa
     5461 ctgcatcaat aagtgcaatt aattcagcta ctcctggtat agttcctata gtattaatta
     5521 atccctcaag agttaaaggg actggaatag gataagatac tctaccagct atatctatta
     5581 aatcacagtt acaagcagaa aatctttcaa aagtaccatc aagtccagat aaattatctt
     5641 ttggaggagc tgaaagatct atacctacca aattagcacc tactataaag aaatctgaga
     5701 taaaagcaaa ttgattaaag tttacaaaag gtcttagagc atcatatctt agaagttcta
     5761 atgcttctct catacttttt ttacaacaac attgttttat tttaggttct ttatatttat
     5821 ttggataatt atagtatcta tcagctactt gataattttc atagtatctt tcatttgtat
     5881 ttggataatc ttcctcatat tcttgtgtaa atctaaagtc ctctctacat ttattatttt
     5941 ccactaaata cactcctttt atattttaat ttaaatgtat agataattaa gcttatctat
     6001 atagtaatat tatatttata atgtaaaaaa atgttacaaa agatattata aacgaataaa
     6061 aaataataat ttgccagata aacttgtaaa tttttatgaa taatccattc taaaacaaaa
     6121 aactgtgtat aaaaaaggtt tatatgttat atttatataa atataacata tgaacgagaa
     6181 aggagtggtt tgataaatga ttgaggtaga taaattgtgt aagtctttta caagggttgt
     6241 aaaagatgat aagaataaaa gttcaataag aaagctaaag aaagtaaaaa ctaaaaaaga
     6301 agaatttttt gctgtaaata atgtttcatt taaagttatg gaaggtgaaa ttgttggaat
     6361 attaggtcca aatggtgcag gaaagactac attacttaga atgttaggtg gcatattaac
     6421 accaacatca ggaagtataa atatttctgg atatgattat tcaatagata gaaattcagc
     6481 aaaaaaagaa ataggttatc tctctggaaa tacaaaacta tatggaaggc tttctccgag
     6541 agaacttcta acaacttttg caagtctata tgagatgtca aaagaagata tagaagaatc
     6601 aattgaaaat attgtaaaaa taatggatat gagtgaattt atagataata gaattgaaaa
     6661 tctatcaact ggtcagactc aaagaacatc tatagctcgt tgtttaatac attctccaaa
     6721 agtatatatt tttgatgagc caacactagg tctggatgtt ttaagtagtg catctattat
     6781 agattttatg aagaatgaaa aactaagggg aaaaactgtt ctttactcaa ctcattatat
     6841 ggaagaagca gaaactttat gtgacaagat ttttatgatt cacaatggga aaataattgc
     6901 atcaggaaca ccacagagtt taaaagagga atctggagta aataatttga gagatgtatt
     6961 cataaaactt gccagaaagg aggacattta aatgagaagt aagattgtaa aatacatatt
     7021 taaaaaagaa atgttagaca tattgagaga taaaaagact ttatttatga tgattgttgt
     7081 gccacttctt ttatatcctt tacttatgtt attaatgatt caagtaatga atatgtctgc
     7141 aagtagtatg aatagtaagg acattaatat agcttttaat aataaaccta ataaggtttt
     7201 agtatccatg attgaagatg ataatttaga aaaagatact aaaaatactt caaatgataa
     7261 aggcaaaata agagtgttag atgtagataa ctataaaaag tcattagaag aaaataaaat
     7321 tgatgcttat ataaagatgg aagaaaaaaa atcatctata aattatcaaa tatatataaa
     7381 ttcttctcaa gaaaattctt ctaatgcact aaaaagaatt gaaactgttt tggataaata
     7441 taaaagattt accatagaaa aaactttatc tgaaaaagga ttagatgtac aagctacttt
     7501 agaaccaata acatatagca ctgtagatgt tgcaaagacg gaagaagtgg caggatactt
     7561 tttaggtcag atacttccat ttatattaat aataggagtt ttactaggtt caatatatcc
     7621 agcaatagat gttatggctg gagaaaagga aagaggtaca ttagaaacat tatttacact
     7681 gccaatatca aacttagaac tggttatggg aaaatatatg gcagtttctc ttagtgcaat
     7741 agtaacagca attttaaaca ttttatctat gggactgact atggcattta ttttagttag
     7801 tggaggtatt agtagccaat ttggctttgg aaactttaat tatggagact tagtcttacc
     7861 aattataact actttaattt gcatatgtct tttttcaatg gtagtttcag caataagtat
     7921 gtgtgtatgt tcattagcaa aaagttttaa agatgctcaa aactacataa cacctcttat
     7981 gttaattatt atgataccat catatgtttc tatgatacca aatatagtat tagatagagt
     8041 gacagctgta atacctgtag taaatatatc tttacttata aaaagtgtat tatcttttaa
     8101 aagcgattta aatttaatag ccttagtttt agcatcaaat gtagcctttg ttatattggc
     8161 aatcatacta ctgtctaaga tgttcaattc tgaggaaata ctttttggta atagtaagag
     8221 tttctctttc ttagagaaaa gaagtaatat aaaaaaaggg tctataccaa ctgtaagtga
     8281 tggtgttatt ttatatgcag taggattagt tctattgatt tatgttggtt ctttagttca
     8341 aattaaattt ggtatggcag gtattataat gacacaattc atgataattt ctttaccgtt
     8401 attatttgca tactatatta aagctgattt taaagaggta tttagcttga aagttcccaa
     8461 attaaagcat gtgtttggga gcattgttct ttggattggt ggatacatac ttattatgat
     8521 tataacacag ctaattttat tcttatttcc tcaaaatatg gaagttgctg aaagtttaaa
     8581 taaggctctt tttatcaaag atagtgtttt actgaattta ctagcaatag ctttattacc
     8641 agctttatgt gaagaaatgt tttttagggg atttatattt tcttcattta gtaaatcaaa
     8701 agataaaaat aagtctatca agctagctat aatatgcagt ggggtactat ttggtattat
     8761 gcatatggat tttattagaa taattccaac atcaatatta ggtattatat ttgcat
//
LOCUS       DAEPKC010000129         8504 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.130, whole genome shotgun sequence.
ACCESSION   DAEPKC010000129 DAEPKC010000000
VERSION     DAEPKC010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8504)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8504)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8504
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.130"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            75..1061
                     /locus_tag="KR294_003361"
     CDS             75..1061
                     /locus_tag="KR294_003361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBH0241411.1"
                     /translation="MKKITINDIANLAGVSKSTVSRYLNNKDISDSTKEKIKTIIDEY
                     GYEPNAFAQSLRAKKTYFIGIITPCLDSFVKSKIMMAIDEELKKLKYTSLIINTNRKI
                     RSEIDSISKLASLKVDGIILIGTEITKEHKNEIEKLDIPIVVVGQKVDGINSIVNDDY
                     GAGYKMGQYIANKGYKNIVYLGVDESDISVGLNRKNGVLNGLKDKGYDAKVFYTDFDQ
                     EMSIQRSGEMLESENPDIIICATDNIAIATMKEINKRGKSIPQDISVAGFGGYDVLSI
                     ISPKLTTIKFENKNAGKVAANTIVNLIQERKEPLLKEIKFELIEGESTINKN"
     gene            1230..1378
                     /locus_tag="KR294_003362"
                     /pseudo
     CDS             1230..1378
                     /locus_tag="KR294_003362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423822.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIB"
     gene            1397..2878
                     /locus_tag="KR294_003363"
     CDS             1397..2878
                     /locus_tag="KR294_003363"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HBH0241412.1"
                     /translation="MYKEPKYRTILESTKEELNKLRNISLNDKYKPLFHIHPQHGLLN
                     DPNGLAYYNGKYHVFYQWYPYDATHGMKHWAYVSSDDFVNWNREDVALIPIESYESHG
                     AYSGNAIEVDGKLHMYYTGNIKYSAEDRYAYQNLAIMNKDGKITKYENNPIVSEIPKG
                     YTGHVRDPKVFKRKDKYFMLLGAQTSDKKGVIIVYESKNSIDWNFKGELNVKNIDEDF
                     GYMWECPDYINIDEKDILIFSPQGVEPKGFDYQNIYNVVYAIGNMDLDNLTFEIDTMK
                     ELEKGFDFYAPQTFIKDSQIILFAWAGMGEVLYPTDKNKWAHCLTVPRKLNIKNNKLL
                     QMPVDELIKLRYDETSGQNTIKNNINIIENDENVYELNINIKNIDSNKFGLELFSSQD
                     EGVKLEFNKLGNIVTLDRSNFKKVFGVEYGTNRKEYINIDENTNIKVLADRSILEIFI
                     NEGEVVFTSRIFAKENSNQIRVYSDKIVEYEYTKFKLKQGIEL"
     gene            2904..3875
                     /locus_tag="KR294_003364"
     CDS             2904..3875
                     /locus_tag="KR294_003364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate kinase"
                     /protein_id="HBH0241413.1"
                     /translation="MKKVISIGEALIDFIPNQNGGKLKNVSEFRRVAGGAPANVSAVV
                     AKLGGKSSFISKLGKDAFGDYIIDVLNEVNVNTDYVLRTSKANTGLAFVSLKEDGNRD
                     FSFYRNPSADMLLEADEVKKEWFNNCHILHFCSVDLIDSPMKLAHKKAIEYALESNSI
                     ISFDPNIRLPLWDSEQSCKKAISEFLPFAHIVKISDEELEFITGENDIEKSLHKLFVG
                     NVELVLYTKGKDGVDAYTKKVKGMCKGVKVNAIDTTGAGDSYIGSFLYTLLYKQITLN
                     DIKEMKQETLNEYLEFSNYYAARSTTIKGAISSYATKEEITEFIKNL"
     gene            complement(4131..4733)
                     /locus_tag="KR294_003365"
     CDS             complement(4131..4733)
                     /locus_tag="KR294_003365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBH0241414.1"
                     /translation="MEVCILMGSPKKKGNTAAILKPFIEELENYNSNIEVIWLYDCKI
                     EPCIACKKCQDNLFDFGCYCKDDVQKIFKKILMCDLIVFATPIYSWYCTSPMKALLDR
                     LVYGMNKYYGNEKGPALWAGKSVALITTCGYRPEKGADIWENGMKRYCKHSQLKYIGM
                     LVERDLGKPNFMNKEKEEHSRQFAKQIYYILSNSIELDNC"
     gene            5014..6225
                     /locus_tag="KR294_003366"
     CDS             5014..6225
                     /locus_tag="KR294_003366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal-dependent decarboxylase"
                     /protein_id="HBH0241415.1"
                     /translation="MYSNEDYKFIEENAPCYIYDETNIIEKCKELKNNILGFDFLYSI
                     KTNPYNKIVKSIAEQGFGADASSTNEVMISSKCGVSKDDIYYSSPGKTEIDIETVLDK
                     CIIIADSITEIELINKISKKHNQKVKIGIRINPDFTMDDDSAKSSKFGIDIEDMSSVF
                     KMLSMCDYVSVVGIHIHIKSQVLDFEKLGHYYEKCFFIALNLNKSKYINIEFINFGSG
                     LGVAYDNLRENPLNLKELSKLTQKIAFTNSNTLKSRLLIESGRFIVCKSGNYYVKIVD
                     IKVSRGKKYLIVKNGLNGFMRPIISNLIENITCGVELEGQEPLYTSNHAFSLSVLNNL
                     KEEEYVNVVGNLCTSLDVIANNVKLKKANIGDLISISNAGSYSYSLSPLLFSSYEFPK
                     QYYKRKDGYIE"
     gene            6293..6490
                     /locus_tag="KR294_003367"
     CDS             6293..6490
                     /locus_tag="KR294_003367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug transporter"
                     /protein_id="HBH0241416.1"
                     /translation="MELWKRNLFVCWIGMFFSSIGMSQIAPILPLYIKQLGVTDVSLI
                     QQYSGIIFGCTFVVAAFFSPI"
     gene            6524..7495
                     /locus_tag="KR294_003368"
     CDS             6524..7495
                     /locus_tag="KR294_003368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH0241417.1"
                     /translation="MLLRASIGMGIVIFTMAFVQNVYQLLGLRILQGVFTGYATACTT
                     LIATQTDKNHSGWALGTLATASTTGSLIGPTVGGYIESILGLKSTFIITGGLLFVSFI
                     ISILFVVDNFKPKEIKESISIPKEQLNILPNKFLIASIFVTTFITQLALYSIEPIVTI
                     YISQLTNFASNVALIAGLTFSASGLANLLAAQKLGKMSDKIGPQKVLLISLLWAGIIF
                     IPQAFVKTAWQLMLLRFLLGLSVAGLNPSVNSLLKKIAPEEYVGKIFGYNASAQYIGC
                     SSGAFLGGQISAHLGIRTVFFSTSLLLFRNALWMYKFTGLFIKDKTK"
     gene            7682..8059
                     /locus_tag="KR294_003369"
     CDS             7682..8059
                     /locus_tag="KR294_003369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBH0241418.1"
                     /translation="MTISKIPQAELKVMKFIWEKNDTVTSKETIEAMERKYGWKQTTT
                     LTLLSRLVKKHFLSAEKIDRYTHYTIVVGHKEYLSVETKDFLSNIHDNSLQSLISALH
                     DDEVVDKDMLDLFESHFKNLEEE"
BASE COUNT         3453 a          886 c         1352 g         2813 t
ORIGIN      
        1 acaaataact atattttatt ttaaatatat aatataatgt aataaaatat atcaaatgta
       61 gaaggtgata acctatgaaa aaaataacaa taaatgatat tgctaacttg gcaggagtat
      121 ctaaaagtac tgtatcaaga tatctaaaca ataaagatat cagtgattct actaaagaga
      181 aaataaagac aataatagat gaatatggat atgagccgaa tgcatttgct caaagtttga
      241 gagctaaaaa aacatatttt attggtatta taacaccgtg tttagattct tttgtaaaat
      301 ctaaaattat gatggcaata gatgaagaac tcaaaaaatt aaaatataca tcactaatta
      361 ttaatactaa tagaaaaata aggtcagaaa tagatagtat atcaaagtta gctagtctaa
      421 aagttgatgg aataatacta attggtaccg aaataactaa agaacataag aatgaaattg
      481 aaaagttaga tataccgata gttgtagttg gacaaaaagt tgatggtatc aatagcatag
      541 tgaatgatga ttatggagca ggctataaaa tgggtcaata tattgctaat aaaggttaca
      601 aaaacattgt atatttaggt gttgatgaaa gtgatatatc agttggttta aatagaaaaa
      661 atggagtact taatgggtta aaagataaag ggtatgatgc aaaagtattt tatactgact
      721 ttgaccaaga aatgtctata caaagaagtg gagaaatgct agaaagtgaa aatccagata
      781 taataatatg tgcaactgat aatatagcaa tagcaacaat gaaagaaatc aataagagag
      841 gtaaaagtat accacaagat atatctgtag ctggatttgg gggatatgat gtattgtcta
      901 ttataagccc taaacttaca acaataaagt ttgaaaataa aaatgcaggt aaagtagcag
      961 caaatacgat agtaaattta atacaagaaa gaaaagaacc actattaaag gagattaaat
     1021 ttgaattaat agaaggtgaa agtacaataa ataaaaatta agatacacat tacatatatt
     1081 agtaatgtgt atttttttac taaaaaaact ataattctaa aaattaggaa aacttttttg
     1141 aaagaaatat tgcatctgaa ataaatttat gctaatcttt aattaaaccg gtttcgaaac
     1201 cggtttaatt aaaccgatag aatagcaaaa tgagtgcaaa aataactgat tgtaacaaag
     1261 tatcaaagta attattggag tacataggaa taaacaaaat ataaaagatg tagcacattg
     1321 tgtaataaga ctaagaattg ttttagatag caataataaa gcaaatataa aattataaaa
     1381 gaaaaggaat aaaaatatgt acaaagagcc taaatataga accatattag aatcgacaaa
     1441 agaagaatta aataaattaa gaaatatatc tttaaatgat aaatataaac cactatttca
     1501 tatacatcca caacatggac tacttaatga cccaaatgga ttagcatatt ataatggtaa
     1561 gtaccatgta ttttatcaat ggtatccata tgatgcaact catggaatga agcattgggc
     1621 ttatgtaagt tctgatgatt ttgtaaactg gaatagagaa gatgtagcat taataccaat
     1681 cgaaagttat gaatctcatg gagcatattc aggtaatgcg atagaggtag atggaaaatt
     1741 gcatatgtat tatacaggga atataaaata tagtgcagaa gatagatatg catatcaaaa
     1801 cttagctata atgaacaagg atggtaaaat aactaaatat gaaaataatc caatagtaag
     1861 tgaaatacca aaaggatata caggacatgt aagagaccca aaagtattta aaagaaagga
     1921 taaatacttt atgttacttg gagcacaaac aagtgataaa aaaggagtta taatagtata
     1981 tgaatctaaa aactctatag attggaattt taaaggagaa ttaaatgtaa aaaacataga
     2041 tgaagatttt ggttacatgt gggaatgtcc agattatatt aatatagatg aaaaagatat
     2101 attaatattt tcaccacaag gagtagaacc taaaggattt gattatcaaa atatatataa
     2161 tgtagtatat gctattggta atatggattt agataattta acatttgaaa tagatacaat
     2221 gaaagaactg gaaaaaggat ttgatttcta tgctccacaa acatttataa aggactcaca
     2281 aataatacta tttgcatggg ctggaatggg agaagtttta taccctacag ataaaaacaa
     2341 atgggcacat tgtctaactg ttccaagaaa attaaatata aaaaataata agctattgca
     2401 aatgccagta gatgaattaa ttaaattaag atatgatgaa acaagtgggc aaaatactat
     2461 aaagaataat attaatatta tagaaaatga tgaaaatgta tatgagctta atattaatat
     2521 aaaaaatatt gacagcaata aatttgggct ggaattattt tcatcacaag atgaaggtgt
     2581 aaaattagaa tttaacaaat taggaaacat tgtaacttta gacagaagca actttaaaaa
     2641 agttttcggt gttgaatatg gaacaaatag aaaagaatat ataaatattg atgaaaatac
     2701 taatatcaaa gtactagcgg atagaagtat tttagaaatt tttataaatg aaggagaagt
     2761 agtatttact agtagaatat ttgctaaaga aaattctaat caaataaggg tttatagtga
     2821 taaaatagta gagtatgagt atactaaatt taaattaaag caaggtattg aattataaaa
     2881 acacattata aggggtagaa aagatgaaaa aagtaattag tataggagaa gctttaatag
     2941 actttatacc taatcaaaat ggtggtaaat taaaaaatgt atcagaattt agaagagtag
     3001 caggaggagc tccagcaaat gttagtgctg ttgtagcaaa gcttggagga aaatcgagtt
     3061 ttatatctaa gttaggaaaa gatgcatttg gtgattatat aatagatgta ttaaatgaag
     3121 taaatgtaaa tactgattat gtattgagaa caagtaaagc aaatacagga cttgcttttg
     3181 tatcattaaa agaagatggt aatcgtgatt tctcatttta tagaaatcca agtgcagata
     3241 tgcttttaga agctgatgaa gttaaaaaag agtggtttaa taattgtcat atcctacatt
     3301 tttgttcagt agatttaata gatagtccaa tgaaattagc acataaaaaa gcaatagaat
     3361 acgcacttga aagtaatagt ataataagct ttgaccctaa tataagatta cctttatggg
     3421 atagtgagca atcttgtaaa aaggcaatat cagaattttt accttttgct catattgtta
     3481 agatatctga tgaagaatta gaatttataa caggagaaaa tgatatagaa aaatcattac
     3541 ataaactctt tgtggggaat gttgaactag tattatatac aaaaggaaaa gatggagtag
     3601 atgcatacac taaaaaagta aaaggtatgt gtaaaggggt taaagtaaat gcaatagata
     3661 caaccggagc aggagattct tatataggtt catttttata caccttattg tataaacaaa
     3721 taacattgaa tgatataaaa gaaatgaaac aagaaacgtt aaatgagtat ttagaatttt
     3781 ctaattatta tgcagctcgt agtacaacta ttaaaggtgc gataagttca tatgcaacaa
     3841 aggaagaaat aactgaattt ataaaaaatt tatagtagga atgagtaata ggttttgaag
     3901 gaagtaacat gtaaagagtt tttaaggatg tttactatga aaataattaa catataaaaa
     3961 gcaataagga ggctgtctca aaatagagat aagcctcttt atcattgttg aaatgataaa
     4021 aaatatttta attattgtta ctttttagaa gaatatatat cttattttaa ataagcaaat
     4081 tatgtaagat ttatttatat tatcaatact ttacttggag tattatgtct ttagcagtta
     4141 tctaattcaa ttgaattaga taaaatataa taaatttgtt ttgcaaattg acgagaatgt
     4201 tcttcttttt ctttattcat aaaattaggt ttacctaaat cacgttcaac aagcattcct
     4261 atatatttta actgtgaatg cttacagtag cgcttcatac cattttccca aatatcagca
     4321 cccttttcag gtctatatcc acatgttgta ataagtgcta ctgattttcc tgcccataga
     4381 gcggggcctt tctcattacc atagtattta ttcattccat acaccaatct gtcaagtagt
     4441 gctttcattg gagaagtgca gtaccaagaa taaattggag tagcaaaaac aattaaatca
     4501 cacataagaa ttttcttgaa aattttctga acatcatctt tacaataaca tccaaaatca
     4561 aataagttat cctgacactt tttacaagca atacatggct ctattttaca atcatataac
     4621 catattactt caatatttga attataattt tctaattcct caataaaagg ttttaaaata
     4681 gcagcagtat tacctttttt cttaggactt cccataagaa tgcatacttc catattgata
     4741 cctccacagt attttaaaat agtttttagt gcttaatata gttttaggat actatgagaa
     4801 tacgttaaca acaatacact ttgtatattt gtaataaaat tgaaacaaat tgttttatca
     4861 ataaaagttg gaatgtatct ataattaaaa atattttagg tatgttttta catatatgtg
     4921 tgtagttaac tatggtaatt tattgtaaaa ttatcttata ggattataat tgcttaattt
     4981 atgattatat ttaaaatctt ggaggtaaaa aatatgtact caaatgaaga ctataaattt
     5041 atagaagaaa atgcaccatg ttatatatat gatgagacta atataattga aaaatgtaag
     5101 gaattgaaaa ataatatttt aggttttgat tttttatatt ctataaaaac aaatccatat
     5161 aacaaaattg taaaaagcat tgcagagcaa ggttttggag cagatgcttc ttcaactaat
     5221 gaagttatga tttcatcaaa atgtggagtt tctaaagatg atatttatta ttcatcacca
     5281 ggcaaaacag agattgatat agaaactgtt ttagataaat gcataattat tgcagatagt
     5341 attacagaaa tagaacttat aaataagata tctaaaaagc ataatcagaa agttaaaata
     5401 ggaataagaa taaatcctga ttttactatg gatgatgata gtgctaaatc aagcaaattt
     5461 ggtatagata tagaagatat gagcagtgtt tttaagatgt taagtatgtg tgattatgta
     5521 tctgtagttg ggattcatat acatattaaa tctcaggtat tggattttga aaagttagga
     5581 cattattatg aaaaatgttt ttttatagct ttaaatttaa ataaaagtaa gtatattaat
     5641 attgaattta taaattttgg tagtggactt ggagtagctt atgataatct tagagaaaat
     5701 ccacttaatc ttaaagagct ttcaaaatta actcaaaaga ttgcttttac taattcaaac
     5761 acactaaaat caagacttct tattgaatca ggacgtttca tagtttgtaa atcaggtaat
     5821 tattatgtta aaattgtaga tattaaagta tcaagaggga aaaaatatct tattgtaaaa
     5881 aatggactta atggatttat gagacctatt atttctaatt taattgaaaa tattacttgt
     5941 ggagtagaat tagaaggtca agagccatta tatacatcaa atcatgcctt ttctctttca
     6001 gtattaaata atttaaaaga agaagagtat gtaaatgttg ttgggaatct ctgtacatca
     6061 ttagatgtaa ttgcaaataa tgttaaattg aaaaaagcaa acataggaga tttgatttca
     6121 attagtaatg ctggaagtta ctcctattct ttatcaccgc tattattttc aagttatgaa
     6181 tttcctaaac aatattataa aagaaaagat ggatatattg agtaaacaat agcataaatt
     6241 aataaactta gtattattga aaaaatttaa aatgcagggg gtgtaattct atatggaatt
     6301 gtggaaaaga aatttatttg tatgttggat aggtatgttt tttagttcta tagggatgag
     6361 ccaaatagca cctatacttc cattatatat taaacagttg ggggtaactg atgttagttt
     6421 aatacaacag tattcaggta taatttttgg atgtaccttt gtagtagcag cattcttttc
     6481 gccaatttga gggaaagctg ctgataaata tggaagaaaa tcaatgcttt tacgtgcaag
     6541 tattgggatg ggaatagtta tatttaccat ggcgtttgtt caaaatgttt atcagttatt
     6601 aggattaaga atacttcaag gagtttttac gggttatgct actgcatgta ctactcttat
     6661 tgcaacacag acagataaaa atcattcagg atgggctttg ggtactcttg caactgcatc
     6721 aactactggc tcattaattg gtccaacagt aggaggatat atagaatcaa tcttaggtct
     6781 taaaagtaca tttattataa caggaggatt gttgtttgta tcatttatca tctctatttt
     6841 atttgtagta gataatttta aacctaaaga aataaaagaa tcaatttcta tacctaaaga
     6901 acaattaaat atattgccaa ataaattttt aattgcatct atttttgtaa ccacattcat
     6961 tactcaacta gctttatact ctatagaacc aattgtaacc atatatatat cacaacttac
     7021 aaattttgca tcaaatgtag ctttaatagc tggattgaca ttttctgcat caggattagc
     7081 aaatttatta gcagctcaaa aacttggaaa aatgtcggat aaaataggtc ctcaaaaagt
     7141 attgttaatt tcacttttat gggctgggat tatatttata ccacaagctt ttgtaaaaac
     7201 tgcatggcaa ctgatgttgt tgagattttt attagggttg tcagttgcag ggcttaatcc
     7261 ttctgttaac agcttgctta aaaaaattgc accagaagaa tatgtgggaa aaatatttgg
     7321 atataatgca tctgcccagt atataggctg ttcatcagga gcatttttag ggggacaaat
     7381 atcagcacat ttaggtatta gaacagtatt tttttcaaca agtttattgt tgtttaggaa
     7441 tgcactttgg atgtataaat ttactggatt gtttattaaa gataagacta aataatcata
     7501 ctatttacat ttctaatttt atgatgtaaa ataaatattt tttatgtaat ttatcataga
     7561 attatataaa aaataaccct atggtaaaaa ttggaaaata ttattatcga caaaatcttt
     7621 gacttaaaaa ctatattgcg atagtattaa tttaataaaa gtttgagagg ggcgtaaggt
     7681 tatgacaatt tcaaaaatac cacaagcaga attaaaagtt atgaagttta tttgggaaaa
     7741 aaatgataca gtaacatcaa aagaaactat tgaagctatg gaacgaaaat atggttggaa
     7801 acaaacaact acattgacac ttttatcaag acttgttaaa aaacattttt taagtgcaga
     7861 aaaaatagat agatacactc attatacaat agttgttgga cataaggagt atttaagtgt
     7921 tgagacaaaa gattttttaa gcaatataca cgacaattct ttacagagtt taatttcagc
     7981 actacatgat gatgaagttg ttgataaaga tatgttggat ttatttgaaa gtcattttaa
     8041 aaatttagaa gaagagtaat tatatcagga tagaactcta agaatttaat taatctatgg
     8101 ctgaaaacca taaatggtat tatttaatca gctactcact attcataaag taatattaaa
     8161 taggttctct aattagtaaa atgcctaaaa taattggaat agggagtatc aagttaaatg
     8221 ataccactta tttaaataag aaatgatttt taaaatttaa aataatttta taacttgtca
     8281 atattcatta atctaaagta ttatttctat ttaaccatat caaaatatat tttactattt
     8341 ttaattatta caatataaac ctgtcttttg ttattatagg taaactaaaa gtaagaaatg
     8401 atttttatat ttttaaactt tattattggt aacttatctg taaatatttt aaaatgtact
     8461 atagaaagtt gttaaaaata ttaaataatt atattaaatt taag
//
LOCUS       DAEPKC010000130         8415 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.131, whole genome shotgun sequence.
ACCESSION   DAEPKC010000130 DAEPKC010000000
VERSION     DAEPKC010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8415)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8415)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8415
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.131"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            172..1623
                     /locus_tag="KR294_003370"
     CDS             172..1623
                     /locus_tag="KR294_003370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine:cation symporter family protein"
                     /protein_id="HBH0241419.1"
                     /translation="MDFFNGILTSINNAVVFVNNYLWSYILIIMLVVIGIYFTIKTNF
                     VQFRYFIEMFRLLGDGTANKNAKKEGKISSFQAFCISTSSRVGTGNIAGIAIAVVAGG
                     PGAVFWMWLIALIGSASSFVESTLAQIYKVKDGQAFRGGPAYYMEQGLNKKWMGILFS
                     ILITICYGFVFNAVQANTVSLAFNNAFGISKMAMGIGLGILTAIVIFGGVHRVAKVSE
                     IIVPVFAGLYILVALAIVVMNITEIPSVIALIVESAFDFKGMAIGTFMGVVMTGVKRG
                     LFSNEAGMGSAPNAAATAHVTHPVKQGLIQSLGVFTDTIIICSCTAFMVLLYSGYSSS
                     GATGIELAQEALTHHIGPVGNIFIAVCIFLFAFSSIVGNYYYGESNMEFMSGSKTKLN
                     VFRVFVVGMVLFGSLTQVDVVWNLADLFMALMAIINLIAIALLGKYAFIALKDYTSQK
                     KSGIKDPVFIADEIEGLEKVSEWHRELSEEHLG"
     gene            complement(1821..2462)
                     /locus_tag="KR294_003371"
     CDS             complement(1821..2462)
                     /locus_tag="KR294_003371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007491147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing protein"
                     /protein_id="HBH0241420.1"
                     /translation="MTDNYIFDSYNNLVDGLSAYLGEGYEFILYKFNGVHYSINKIAN
                     GKYNTVKEGDIITDFDLALINKLENDADGDFISYFNRNKLGEPLKSTDIVIRGVDNKI
                     IGLLCIHFYLNTPLTRIIGSYIPEHNAMQSAPVLENIVEDTDEVILKSYQDAKVIVEN
                     DSNISSNDKNKSIVSILNESGIFKIKDSVVKVADLMGLSKNTIYMHLRNLNKN"
     gene            2936..4315
                     /locus_tag="KR294_003372"
     CDS             2936..4315
                     /locus_tag="KR294_003372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016290023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBH0241421.1"
                     /translation="MAQDKIVVEILENIGGKENIKEVAHCMTRLRIKVCDSSQVNQEK
                     LKKIKGVLGLVLKGEQYQIVIGPNVSQVYNTLNEVIGIIPEKDSKKTISEGKQNSIAK
                     ILDTIAGIFNPIVPALAGAGLIKAILALLVASKFLSADSETYIILNTISDGVFSFLPF
                     MLAYSAAKIFKMNTYVAVAIAGAMLHPNFINLIQQGLTKISFIGIPMSLIQYNGSVFP
                     IVLTIWFASYIEKGVDKITPKALKIILVPALTILFAAPIALIIIGPIAQMLGNYIAGG
                     ASILFERGGIFAGLIYGGIYSFMVVTGLHHGMVPVLVDGITRYGFNYISPVSGSSNMA
                     QAGSAFGVWLKAKDKDLKAVAATATISALTGVTEPAIYGVNLRLKKPFLCAAIGGAAG
                     GGFAAYFQCKAFAMGGPSFLTLPMFIGEGGHVGLVAIAFTIAFIVSAIATYIVGFEEE
                     VTADSHANL"
     gene            4359..5093
                     /locus_tag="KR294_003373"
     CDS             4359..5093
                     /locus_tag="KR294_003373"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010990049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HBH0241422.1"
                     /translation="MKIYLTKDYEEMSQVAAQMVLKYMYSNDNKRINLSITAGQTPKR
                     TYEILSEFVKNKPYFENVHYYNFDEIPIKGEKVGVTIRNLTNMYFREAQIPEERIHVL
                     DENNYQGFDRKIEADGGIDMVLMGLGWDGHFCGNLSGTVNSFDEETRAVSTYITDDMA
                     KLLTKSVGGNPEKLFDYYVTYGPKTIMHCKNIIMIVNGKHKAQILKQTLFGPLDLLCP
                     SSLLRLHPNFTLIVDEEAASEIKDLI"
     gene            5182..6381
                     /locus_tag="KR294_003374"
     CDS             5182..6381
                     /locus_tag="KR294_003374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006875852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBH0241423.1"
                     /translation="MYNHMKKVFQGLEGGLFSSVEKADVGDSYQKLGEQGVSLMGWAD
                     PFFPDYCIPRHILDAATLAISSNMSTHYTAPVGNDLLKIEIAEKLKEVNNLDVDFKRN
                     ILITPGSDSGLYYSMLPFINEGDEVLIPTPCYPNNIQNTKLMGGVPIFVELKESDGYQ
                     IDITEFEKRLTNKTKLVVLTHPNNPTTTIFNKESLEKLAKFIIDNDLILICDQAFEDF
                     TFENELITPASLEGMFERTVTIFSTSKGMGLSGFRVAYMVCSDKLMDKYYGAAVTVLG
                     ATNTVAQMSTIEAFKDRSFMEDFERVFDKRRQEAYKIINEIPNVSMQMPESGFLGWIN
                     VSKLGTSSEIQKYLVDEAKVCINDGINYGPGGEGHLRIILGSYKDDSKVIGALNRIKD
                     ALIKKQQ"
     gene            6405..6887
                     /locus_tag="KR294_003375"
     CDS             6405..6887
                     /locus_tag="KR294_003375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015529974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBH0241424.1"
                     /translation="MLSIFKSKKNDNKLKAFASGKVIPIEDVDDNVFSSKMLGDGIAI
                     YPTNEYVVAPCDAEVNIIMKDTKHAVGIKLFNGMEILFHVGIDTVSMNGEGFEIFVSP
                     GDKIKRGDKLISFNSKLIKEEGLQDVVIMVVTNSEQYKNIKYHIGLEAVIDDTIIAEI
                     "
     gene            complement(7205..7802)
                     /locus_tag="KR294_003376"
                     /pseudo
     CDS             complement(7205..7802)
                     /locus_tag="KR294_003376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816433.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(8046..>8415)
                     /locus_tag="KR294_003377"
     CDS             complement(8046..>8415)
                     /locus_tag="KR294_003377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241425.1"
                     /translation="SLTLNEDLIWEFKHGKYHTIKYFTHKFAVKESVLALLFNIHKLC
                     YAKIKYFESSFSKYEPYKYSYQNEFVKCEMYDMNFMFHKYSNIMIDLRNLQEIKTIEE
                     FRLFCDYLESFEDNLQDLII"
BASE COUNT         3115 a          970 c         1392 g         2938 t
ORIGIN      
        1 gatttgaata taaaactgca atatattaaa aaaattattc attttaaacc ttgtaatttg
       61 attttataaa tattataatt aaattaatga atttttaaca aggaattatt catttttttg
      121 attttaagat ttattgagaa aacaaaacta aatagggggg taattaatat aatggatttt
      181 ttcaatggta ttttaacgag tattaacaat gcagtagtat ttgtaaacaa ttacttatgg
      241 tcgtatatct taattataat gttagttgta attggtattt actttactat taaaacaaat
      301 tttgtacaat tcagatattt tatagaaatg tttagacttc tgggtgatgg tacagcgaat
      361 aaaaatgcaa aaaaggaagg aaaaatctct tcatttcaag cattttgtat aagtacatct
      421 tcaagagttg gaactggaaa tatagctgga atagcaattg cagtggtagc aggaggacct
      481 ggtgctgtat tttggatgtg gcttatagca ttaattggtt ctgcatcaag ctttgttgag
      541 agtacattag ctcagattta caaagtgaaa gatggtcaag cttttagagg tggaccagcg
      601 tattatatgg aacaaggtct aaataaaaaa tggatgggta ttttattctc aatacttata
      661 actatatgtt atggttttgt atttaatgca gttcaagcaa atactgtttc acttgcattt
      721 aataatgcat ttggaataag taaaatggct atgggaatag gtcttggaat tttaactgca
      781 atagttattt ttggtggagt gcatagagtt gcaaaagttt ctgaaataat agttcctgta
      841 tttgcaggat tatatatatt agttgctttg gctatagttg taatgaatat aacagagata
      901 ccaagtgtta tagcattgat agttgaaagt gcatttgatt ttaaaggaat ggcgattggt
      961 acatttatgg gagttgtaat gactggagtg aagagaggtc tattttctaa tgaagcaggt
     1021 atgggtagtg ctcctaatgc tgctgcaaca gcacatgtaa ctcatcctgt aaaacaaggt
     1081 ttaattcaat ctttaggtgt ttttacagat actataataa tatgtagttg tacagcattc
     1141 atggtattat tatattcagg ttatagtagt agtggagcaa ctggaattga attagctcaa
     1201 gaagctttaa ctcatcatat aggaccagtt ggaaatatat ttatagcagt ttgtatattc
     1261 ttgtttgcat ttagttctat agttggtaat tactattatg gtgaatcaaa tatggagttt
     1321 atgagtggaa gtaagactaa acttaatgta tttagagttt ttgttgtagg tatggtttta
     1381 tttggttcac ttactcaagt ggatgtagtt tggaatcttg cagacttatt tatggcattg
     1441 atggcgataa taaacttaat agcaatagca cttttaggaa aatatgcatt tattgcttta
     1501 aaagattata caagtcaaaa aaaatcagga ataaaagacc ctgtgtttat tgcagatgaa
     1561 atagaaggcc tagaaaaggt atcagagtgg catagggaat tatctgagga acatttagga
     1621 taaaaaatag tataaaatta taaaaccatt ttgaaagact agagtatgta tatactttat
     1681 atgaatataa tattgaatta atttatatta ctggaatttt taattccagt aatatttttt
     1741 taattacaag gatattatga tgacttaaag actgtggaaa actctttttt agttttcatt
     1801 attaatatta attgacaaat ttagttttta tttaaatttc ttaagtgcat ataaatcgta
     1861 ttttttgata atcccattaa gtctgcaact ttaacaacag aatccttaat tttaaaaata
     1921 ccactttcat ttaaaataga aacaatagat ttatttttat cattgctaga tatattagaa
     1981 tcattttcaa caattacctt tgcatcttgg tatgatttta aaattacttc atcagtatct
     2041 tctacgatat tttctaaaac aggagcactt tgcatagcat tatgttccgg aatatatgaa
     2101 ccaattattc ttgttagtgg tgtattaaga taaaaatgta tgcagagtag accgattatt
     2161 ttattatcaa ctccccttat cactatatct gttgatttta aaggttcacc tagtttgttt
     2221 ctattaaaat aactgataaa atctccatca gcatcatttt cgagtttatt aatgagtgcc
     2281 aaatcaaaat cagttataat atctccttct tttacagtat tatatttacc attagctatt
     2341 ttatttattg aatagtgtac tccattaaat ttatataaaa taaactcgta tccttctcct
     2401 aaatacgcag ataatccatc cactagattg ttataagaat cgaaaatata gttatcagtc
     2461 atgttaaaag tcatatgtta cctcctaaga aatatcttaa tatcatatta acatataaaa
     2521 tgaatttaat aaaatatatt tcagtgaaat aataaatata atgaaaaaaa aactattgac
     2581 tgaaaaatat ttcagtgata ttattaaaat acagtaaggc aaacgtatta ttgacagaat
     2641 atataaaatg ttaaaaatag tatctaggaa ttaaacaaat taaaggacta gtgatttgaa
     2701 tttttttagt ataatatgtg acttccaatt aatatttatt aaacaccaat aaaattgtaa
     2761 atatgcttaa tgatatactt tagcgatgaa gtgaaaatat tttattttta tgattaacct
     2821 ataggaatta atttagcata ctgtttagct agtaaatcta aataaatttt agctttagct
     2881 gatatcatgt tgaataaagt ttctattgga ttttgtataa caaaggagtg gggagatggc
     2941 acaagataaa attgtggttg aaattttaga aaacattggt ggtaaggaaa atattaagga
     3001 agtagcacat tgtatgacta gactgagaat aaaggtatgt gatagttctc aggtaaatca
     3061 ggaaaaacta aagaaaataa aaggtgtact aggtcttgta ttaaaaggtg agcaatatca
     3121 aattgttata ggtcctaatg tatcacaagt gtataatact cttaatgaag ttataggaat
     3181 tatacctgag aaggatagta aaaaaacaat atctgaaggt aaacaaaata gtattgcaaa
     3241 aatattagat actattgcag gtatttttaa tcctatagtt ccagcattag cgggtgcagg
     3301 tctaataaaa gctatattag cattactagt agcatcaaag tttttatctg cagatagtga
     3361 aacctatata atattaaata caatatctga tggtgtattt tcatttttac catttatgtt
     3421 agcttactca gcagctaaaa tatttaaaat gaatacttat gttgctgtag caatagcagg
     3481 agcaatgcta catcctaatt tcattaattt aattcaacaa ggcttaacta aaatatcttt
     3541 tatcggtatt ccgatgtcac taatccagta taacggaagt gtatttccga tagtactaac
     3601 tatttggttt gcatcgtata tagaaaaagg agtagataaa ataacaccaa aggcacttaa
     3661 gataatatta gtacctgcat tgactatttt atttgcagct cctatagcat taattattat
     3721 tggaccaata gctcaaatgc taggaaacta tatagccggt ggagcaagta tcctatttga
     3781 aagaggagga atatttgcag ggttaattta cggaggaatt tattcattca tggtagtaac
     3841 aggattacat catggtatgg ttcctgtatt agtagatgga ataacaagat atggatttaa
     3901 ctatataagt cctgtgtcag gtagttcaaa tatggctcaa gcaggatctg catttggagt
     3961 atggttaaaa gcaaaagata aagatttgaa ggctgtagca gctacagcta ccatatcagc
     4021 attaactgga gttaccgaac ctgcaatata tggtgttaat ttaagattaa agaaaccgtt
     4081 tttatgcgct gctataggtg gtgcagcagg aggtggattt gctgcatatt tccaatgtaa
     4141 agcatttgct atgggaggtc catcgttttt aactcttcct atgtttatag gagaaggtgg
     4201 acatgtagga ttggtagcaa tagcatttac aatagcattt atagtatctg caatagctac
     4261 ctatatagta ggatttgaag aagaggtaac agcagattca cacgctaact tataataaag
     4321 agaaattatt taacatatca aaaaggagat taattactat gaaaatttat ttaactaaag
     4381 attatgaaga aatgagccaa gtggcagcac aaatggtgtt aaagtatatg tacagcaatg
     4441 ataataaaag aataaacctt tctataacag caggtcaaac accaaaaaga acatacgaaa
     4501 tattaagtga atttgttaag aataaacctt attttgaaaa tgtacattat tataactttg
     4561 atgaaatacc aataaaaggc gaaaaagttg gagttactat aagaaattta actaatatgt
     4621 actttagaga agctcaaata ccagaagaaa gaatacatgt gttagatgaa aataattatc
     4681 aaggctttga tagaaagata gaagccgatg gtggaataga catggtatta atgggattag
     4741 gttgggatgg acacttctgt ggaaatctta gtggtacagt caactctttt gatgaagaga
     4801 caagagctgt ttcaacttat ataacagatg atatggctaa actattaaca aaatctgtag
     4861 gtggaaatcc agaaaaatta tttgattact atgtgacata tggacctaaa acaataatgc
     4921 attgtaaaaa tataataatg atagtaaacg gaaaacacaa agctcaaata ttaaagcaaa
     4981 cactatttgg accattagat ttattatgtc catcatcttt attgagatta catcctaact
     5041 tcacattaat agtagatgaa gaagcagcat ctgaaataaa agatttaata taaataagta
     5101 aggaattaaa attaaaaatg aatttaggtg caaagtaata ttttattttg cacctttgct
     5161 ttaataaaaa ggagaataaa aatgtataat catatgaaaa aagtattcca aggattagag
     5221 ggtgggttat tttcaagtgt agagaaagct gatgtaggcg attcttatca aaaattaggt
     5281 gagcagggtg taagtttaat gggatgggca gatccatttt tcccagatta ctgtatacct
     5341 agacatatat tagatgcagc tacattagcg atatcaagta atatgtcaac tcattataca
     5401 gcgcctgtag gtaatgactt attaaaaatt gagatagcag aaaaattaaa agaagtaaat
     5461 aatttagatg ttgattttaa aagaaatata ttaataactc ctgggtcaga ctcagggctt
     5521 tattactcaa tgttaccgtt tataaatgaa ggggatgagg ttcttatacc aacaccatgc
     5581 tatccaaata atatacaaaa tactaaatta atgggaggag ttcctatatt tgtagagtta
     5641 aaggaatcag atggatatca aatagatata acagaatttg agaagagatt aactaataag
     5701 acgaagttag tagttcttac tcatcctaat aatccaacaa ctacaatatt taataaagaa
     5761 tctttagaaa aattagctaa atttattata gacaatgatt taatattaat atgtgatcaa
     5821 gcatttgaag attttacttt tgaaaatgaa ttaataacac cagcttcatt agaaggtatg
     5881 tttgaaagaa cagtaacaat attttcaaca tcaaaaggta tgggattaag tggatttaga
     5941 gttgcatata tggtatgcag cgataaatta atggacaaat actatggagc agcagtgaca
     6001 gtattaggtg ctactaatac agtagctcaa atgtcaacga ttgaagcatt taaagataga
     6061 agctttatgg aggattttga aagagttttt gataaaagaa ggcaagaagc atataagata
     6121 atcaatgaaa tacctaatgt atctatgcag atgcctgagt ccggattttt aggttggata
     6181 aatgtatcaa agcttggaac atcatcagaa atacaaaagt atctagttga cgaggctaaa
     6241 gtttgtatta atgatggaat taattatggt ccaggaggag aagggcattt gagaataatt
     6301 ttaggaagct ataaagacga tagtaaggta attggtgcat taaatagaat aaaagatgct
     6361 ttaattaaaa agcaacaata aataaaaaat aattggagtg gagtatgtta tcaatattta
     6421 agagtaaaaa aaatgacaac aagcttaagg catttgcatc agggaaagta attcctatag
     6481 aagatgttga tgataatgtt ttttcatcta aaatgttagg tgatggaatc gctatttatc
     6541 caactaatga atatgttgta gccccttgtg atgcagaagt aaatataata atgaaagata
     6601 ctaaacatgc agttggaatt aaattattta atggtatgga aatcttattt catgttggaa
     6661 tagatactgt atctatgaat ggagaaggtt ttgagatatt tgtttcacca ggtgacaaga
     6721 taaaaagagg tgataaatta atatctttta atagtaaatt aataaaagaa gaagggttac
     6781 aagatgtagt tataatggta gttactaatt cagaacagta taaaaatata aaatatcata
     6841 ttggactgga ggcagtaatc gatgatacta ttattgcaga aatttaaaaa cagttattta
     6901 agtaaatact tagataattt agatatagtt aaaattaaat ccttaaaatc aaattattta
     6961 atttttgtgt aattttaact ataaagccga ttaataatat aaagtatact aaataatatg
     7021 gttattatga ttgttactga caaagcctaa gtagatataa caatttgctc taattgagta
     7081 ttgctatatc tacttgtttt tatatttaaa ataaaagagt ctgcattgaa aagataattc
     7141 tgatgagagt aaatagggta tttaataata gtttaattct gacttatcaa gatgaaccta
     7201 ttcatatacc taaaacatct ttaacacctt ctaaattcat acaaatagct gtataggctg
     7261 ccttattgat tatttttccg tcaattttta ctttgtagtg aacagcatat ataaatatta
     7321 tcgaatagat tgtatcaaga gctctatttt gctattcatt agctaaagat agtactctgt
     7381 cagttatttt tgaaactaat gcatgagata tatcaattcc gtaaatatta tttaaatgta
     7441 tgatatatat cgcgagtcga cattcctttt gagtacatgc caattacttg gttctctatt
     7501 ccagaaattt cattttcgta attttgaata accctaggct ggaaatcatc cctagggata
     7561 tttaatttta cctctccaaa atctgattta acattcttag ctctatatcc atttcttgaa
     7621 tttgatgttg ctttactttg gttatcatat ctctcgtaca ttaaatgatc ttcaatctct
     7681 gactctaaca ttttgtgaat tgtgcttgcg aataaatctt ttaacatctc ttggatgtct
     7741 ttagtatttt ttacatcata ctcttgaact aagtgtttta atatttaatt tttgttgtac
     7801 ataaaaaatg tgtacctcct attttggtaa ttagatttaa tatcttgact tttaggagaa
     7861 tacacatttt attttacaga ccctcttttc tagaaaagtt tttatgaaaa ttgtgatata
     7921 aattattaat aaaaaataat tttatattta ttttattatg taatttagtt ttattaaaaa
     7981 ttttttatta ttggatatag attatctatt ataaatttta tctttaagtt tattctccta
     8041 aaatactata taattaaatc ctgtaaatta tcttcaaagc tttctaggta atcacaaaat
     8101 aatctaaatt cttctatggt tttaatttct tgtaaatttc tcaaatctat cattatatta
     8161 ctatatttat gaaacataaa attcatatca tacatttcac atttaacaaa ttcattttga
     8221 taactatatt tataaggttc gtattttgaa aaactcgact caaaatattt tattttagca
     8281 taacataatt tgtgtatgtt gaacaaaagt gcaagaacag actccttaac tgcaaactta
     8341 tgtgtaaagt attttatcgt gtggtattta ccatgtttaa actcccaaat taaatcctca
     8401 tttaaagtaa gagaa
//
LOCUS       DAEPKC010000131         8402 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.132, whole genome shotgun sequence.
ACCESSION   DAEPKC010000131 DAEPKC010000000
VERSION     DAEPKC010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8402)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8402)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8402
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.132"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            66..266
                     /locus_tag="KR294_003378"
     CDS             66..266
                     /locus_tag="KR294_003378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241426.1"
                     /translation="MEKLKTISVFSLIISVILTIGGIGIVTYYVDNLFIRGLSVFVLI
                     MSSSFVSTTVRLIFEESKRYKF"
     gene            complement(473..1063)
                     /locus_tag="KR294_003379"
     CDS             complement(473..1063)
                     /locus_tag="KR294_003379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipicolinate synthase subunit B"
                     /protein_id="HBH0241427.1"
                     /translation="MRLEGLTIGVGFTGSFCTYDKIFIELENLVKEGANVHTIFSDVS
                     QNIDCRFGNSEEFMKKAYELTGNKPIVTIEEAEPFGPKGIADIIIIAPCTGNTAAKLA
                     NGITDSPVLMAAKGHLRNDKPLVISISTNDALSFNFKNIGILLNSKNIYFVPFGQDNC
                     KAKPNSMIAHTELIIPTIELALENKQLQPVIKSPHQ"
     gene            complement(1066..1941)
                     /gene="dpsA"
                     /locus_tag="KR294_003380"
     CDS             complement(1066..1941)
                     /gene="dpsA"
                     /locus_tag="KR294_003380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipicolinate synthase subunit DpsA"
                     /protein_id="HBH0241428.1"
                     /translation="MSNQYDITVIGGDLRQVYMVKKLINKGYSVVTYGISNEIINGIV
                     GKSTSLAEALSKSSIILCPIPFTKNQVNIENTDDCLDATIDNLLINLSPNQILFGGNI
                     PTKVCKFCEQHSIQIYDFMKMNDVAILNAVATAEGAIAEAIKRSIINIHQSNCLVLGY
                     GRCAQILAKKLYALDANVCVGARNNDARSTANAFGYSSISLSQLDEKLLQFDYIFNTI
                     PECILTKERLEKVSQEVTIIDIASSPGGVDYSVVKEAGINATLCLGLPGKYSPKTSGE
                     ILVNAIENIINERRD"
     gene            complement(2017..3408)
                     /locus_tag="KR294_003381"
     CDS             complement(2017..3408)
                     /locus_tag="KR294_003381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HBH0241429.1"
                     /translation="MNYYELLRIKKERHKNKNFLIIDGEKYTYENILSYSEELGKQIS
                     LGENIPILIYSKNIMFQLISFFAINYSKNIPIICHYNLSKKVLDDILLKNNISIIISD
                     ESMDVIDLYDDNNNEVAKKVNFSIFNPKFNIYMYQYKNLINYLDKSICMGALSSGSTS
                     VPKVLYRTYESWAGFFPIQNGIFNISGESILFVNGTLSFTGNLNSIMSVLYEGGSIVI
                     SSGLNCKSWIRIIKQYNVTNIYLIPTKLQLLVKHLKEPVLKVVSIFTGSQLLFEDTAR
                     NLKKYMPKSEIILYYGASELNYITYLCYDELIEKPLSVGRPFPGIDIYIREGKIFVNT
                     EYAVYNATKPYSVNDIGYYDNDGYLIFEGRSDDILNIGGFKVSSTKIENEVKKIPQIE
                     DAIVLPYSDTIRGNQIVLFVITIDKITKKDLLIKMKDNLMKNEIPKKIIFLNSFPYTS
                     SEKIDRLALLKML"
     gene            complement(3412..4548)
                     /locus_tag="KR294_003382"
     CDS             complement(3412..4548)
                     /locus_tag="KR294_003382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiolase family protein"
                     /protein_id="HBH0241430.1"
                     /translation="MKEVFILGGLRSHIGLKNGIFQFVQPELLGASVLKDLIKKYEID
                     KIDEIICGNAVGTGGNIARLMTLTAGVSNEVPAFTVDMQCASAMMSIDIAFSKVKSGQ
                     CDLIIAGGFESSSLQPMRTYHKNDKRYNTNNPNYTVAQFSPDDNSQNSMLEGAERVAE
                     LYQIEKADLDFWVKESHKRAKEAREEKILEDIISPINNSTYDEGIRDKMSQRLLDRMP
                     SILGKETITNAANSCLINDGASFIIICSKKYLEHVKKKPKAKIINTCTIGTDATLSPT
                     SAIQAMDKLLEIESLNYLDVSAVEFNEAFAVIDVLFQRKYPELIDRYNIFGGALAYGH
                     PYGASGAIIALHLLKALEKTKGRYGICSIAAAGGLGSALLLERV"
     gene            complement(4580..5125)
                     /locus_tag="KR294_003383"
     CDS             complement(4580..5125)
                     /locus_tag="KR294_003383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HBH0241431.1"
                     /translation="MKNTKVNIQDLTKMSICVALLCISSYIYIPLPFTPAGVTAQTIM
                     INLIALILTPRQAFSTVGVYIMIGLIGIPVFGGGTSGIGKLLSPTGGFYFGFLFAALI
                     ISLLKGRNNDIKRYILITIFVGMPIIYFMGTVFMCYFNQMTVEAALFAAVVPFLIGDT
                     IKSVIASFLGTKLNNVLRRNL"
     gene            5449..6228
                     /locus_tag="KR294_003384"
     CDS             5449..6228
                     /locus_tag="KR294_003384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241432.1"
                     /translation="MKVNENNINNIDEELDELSRKVYLESPDFWISISDKIIDKVFDE
                     MLLFFAVKYNYFNIVCFAIENNYLDLNMPSKNKKYTNIMEHLLDTSKQNEDKKIYNYL
                     LSLNKGNNLDERPILDELNCNISSDTFEKKDIYLPKYLCPSCNSNIFDTGYKVSNDIT
                     YKFSSKEAEPIEMCSEVSSIRCCNCDELLEDITLDKLYNLCKIQNCNNCGSNLTKVGI
                     IAKKKMNFDENTEKFKDVSTSYCCGNCDSEINLSQREHFKI"
     gene            complement(6683..7111)
                     /locus_tag="KR294_003385"
     CDS             complement(6683..7111)
                     /locus_tag="KR294_003385"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HBH0241433.1"
                     /translation="MIKKLNNKDINKIMEIWEKSTIKAHDFISKEYWQNNYNTVKNEY
                     IPISDTFVYDDGDEIKGFISIIDKSFIGALFIKPKYQNLGIGGKLLDYATKKYKSLSL
                     AVYKDNKKAVVFYNKKGFNIVKEQVNEDSGFKEYIMEYSK"
     repeat_region   7172..8376
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=7367..7395
                     /rpt_unit_seq="atttacataccacttagttaatataaaac"
BASE COUNT         2999 a         1254 c          953 g         3196 t
ORIGIN      
        1 atatgaaata aaatatattt aatattatat agataaattt gaagtttata agaaggagga
       61 taagcatgga aaaattaaaa acaattagcg ttttttcttt gattataagt gtaattttaa
      121 cgattggagg tattggaata gtaacttatt atgtagataa tttgtttatt agaggactat
      181 cagtatttgt tttaattatg tcctcttctt ttgtatcaac aacagttaga ttgatatttg
      241 aagagtcaaa acgatataaa ttctaattta aaaattggat taagtaaata attttaatat
      301 agcaaaaatt acggagatta gctcaaaata gactttttag tccatgaggc atttttttgt
      361 atgaaattaa atatattttc atcatttcaa caagaaaaag aggcttctct ctattttgag
      421 acagcctctt tgctagtatt gtatctaata cataatatta taagaaccaa ttctattgat
      481 gtggactttt tataacaggc tgtagctgtt tgttctctag agcaagttct atagttggaa
      541 ttattagctc agtatgtgca atcatagaat taggctttgc tttgcaatta tcttgaccaa
      601 aaggtacaaa atatatattt ttagaattaa ggagaatgcc aatatttttg aaattaaagc
      661 ttagagcatc attcgttgat attgatatta ctagtggttt atcattacga agatgacctt
      721 ttgctgccat taatactggt gaatctgtaa taccatttgc taattttgca gcagtatttc
      781 cagtacaagg agctattatt ataatatcag caattccttt aggtccaaat ggctctgcct
      841 cttcaatcgt aactataggt ttatttcctg taagttcata tgcttttttc ataaactctt
      901 cagaatttcc aaatctacaa tcgatatttt gtgatacatc tgaaaatata gtgtgtacat
      961 tagctccttc tttaaccaaa ttctctaact ctataaatat tttatcataa gtacaaaacg
     1021 aaccagtaaa tcctactcca attgtaagtc cttcaagtct catttctaat cccttctttc
     1081 atttataata ttttctatag cgttaacaag aatttcacca gatgtctttg gtgaatattt
     1141 accaggaagc ccaaggcaaa gagtcgcatt aatccctgct tctttaacaa cagaataatc
     1201 tactcctcca ggagaagaag ctatatctat aatagttact tcttgtgata ctttttctaa
     1261 cctttctttc gttaaaatac actctggtat ggtgttaaaa atataatcaa attgtaaaag
     1321 tttttcatca agttgactta aagaaatact ggaatatcca aatgcattag ccgtacttct
     1381 tgcatcatta tttcttgcgc caacacatac atttgcatcc aaagcgtata atttttttgc
     1441 aagtatttgt gcacatcttc cataacctaa tactaaacag ttactttgat gtatattgat
     1501 tatacttctt ttaatagctt ctgctatagc cccttcagct gtagcaactg catttaaaat
     1561 agcaacatca ttcattttca taaaatcata aatctgaata gagtgttgct cgcaaaattt
     1621 acaaacttta gttggtatgt tacctccaaa taatatttga ttaggagata aattaattag
     1681 caagttatca atagtagcat caagacaatc atccgtattt tcaatattaa cttgattctt
     1741 tgtaaatgga attggacata aaataatgga acttttggat agtgcttcag ctagtgaagt
     1801 tgattttcca acgattccat ttataatttc atttgatatc ccataagtga ctacagaata
     1861 ccctttatta attagttttt ttaccatgta cacttgtcgc aggtctcccc caataacagt
     1921 tatatcgtat tgatttgaca tattgtaagc ctcctttact atatacaata tgtttttatc
     1981 aatacattgg ttcactaaaa ttactaaata ttatacttat aacattttta ataatgctaa
     2041 tctatctatc ttttcagaag aggtatatgg aaatgaattt aaaaagataa ttttctttgg
     2101 gatttcattt ttcattagat tatctttcat tttaatcaac aaatctttct tcgtaatttt
     2161 gtctatagtt attacaaata atacaatttg atttcctctt atagtgtctg agtacggcaa
     2221 tacaattgca tcttcaattt gaggaatttt tttaacttca ttttcaatct tagtagaact
     2281 aactttaaat cctccaatat ttaaaatgtc atcacttctt ccttcaaata ttaagtatcc
     2341 atcattatca taatatccaa tatcattgac agaataaggt ttggttgcat tatatactgc
     2401 atattctgta ttcacaaaaa tttttccttc tctaatatat atatctattc ctggaaatgg
     2461 tctgcctaca cttagaggtt tttcaattag ttcatcatag cataaatatg taatataatt
     2521 taattcactt gccccatagt ataaaataat ttcagacttt ggcatatatt tttttagatt
     2581 tcttgcagta tcttcaaata ataattgaga ccctgtaaaa atacttacaa ctttgagtac
     2641 tggttctttt aagtgtttaa ccaaaagttg aagttttgta ggtataaggt atatgttagt
     2701 tacattatat tgttttatta tccttatcca tgatttacaa ttaagacctg aacttattac
     2761 aatactacct ccttcatata atactgacat tatagaattt agattccctg taaaactaag
     2821 tgttccatta acaaacaaga ttgattcccc agagatatta aaaataccat tttgtatagg
     2881 aaaaaatcca gcccaactct catatgttct atataatacc tttggaacac ttgtagaacc
     2941 tgaagataaa gctcccatac aaatactttt atctaaataa tttataaggt tcttatattg
     3001 atacatatat atattaaatt taggattaaa aatagaaaaa ttaacttttt ttgctacttc
     3061 attattgtta tcatcatata aatcaataac gtccatagat tcatcagata taatgattga
     3121 aatattattt tttaataaaa tatcatctaa tactttttta gaaagattat aatgacaaat
     3181 aataggaata ttttttgaat aattaatagc aaaaaaacta atcaactgaa acattatatt
     3241 tttagaatat attaaaattg ggatattttc acctaaagaa atttgttttc ctagttcctc
     3301 actataactc aatatatttt cataagtata tttttctcca tctataatta aaaaattttt
     3361 atttttatgc ctctcttttt ttattcttaa aagttcataa tagttcataa tctacaccct
     3421 ttcaagcagt aaagctgaac ctagaccacc agctgcagct atagagcaaa ttccatatct
     3481 acccttagtc ttttctaatg cttttaaaag atgtaatgca ataattgcac ctgaagcacc
     3541 atatggatgt ccatacgcta aagctccacc aaatatatta tatctatcta ttaactctgg
     3601 atattttctt tgaaacaaca catctataac tgcaaatgct tcattaaatt caacagcaga
     3661 tacatctaaa taattaagac tttctatctc taaaagttta tccattgctt gtatcgctga
     3721 tgttggactt aaggttgcat ctgttcctat tgtgcatgta ttaataattt ttgctttagg
     3781 cttctttttt acatgttcta aatacttctt agaacatatt ataataaatg aagctccatc
     3841 attaataaga catgaatttg ctgcatttgt aatagtttct tttcctaaaa ttgatggcat
     3901 cctatctaat aacctttgac tcatcttatc acgtatacct tcatcatagg tactattatt
     3961 tataggagat ataatatctt caagtatttt ttcctctctt gcttcttttg ctcttttatg
     4021 actttccttt acccaaaaat ccaagtctgc tttctcaatt tgatataact ctgctactct
     4081 ttccgcacct tcgagcatac tattttggct attatcatca ggagaaaatt gagcaactgt
     4141 ataatttgga ttatttgtat tatatcgctt atcattctta tgatatgtgc gcattggttg
     4201 tagagaacta ctttcaaaac cacctgcaat aattaaatca cactgaccag atttaacctt
     4261 tgaaaaagct atgtctatac tcatcatagc agaagcacac tgcatatcca cagtaaaagc
     4321 aggtacttca tttgacactc ctgctgttaa agtcattaat ctagctatat tccctcctgt
     4381 cccaactgca tttccacata taatctcatc aattttatca atttcatact ttttaattaa
     4441 atcttttaaa acacttgctc ctagtaattc aggttgaaca aattgaaaaa ttccattttt
     4501 tagacctata tgacttctca atcctcctaa tataaaaact tccttcatac attacaccct
     4561 tccttatatt atagatttat catagatttc ttctgagtac attgttcagt ttagtgccta
     4621 aaaaagatgc aataactgac tttattgtat ctccaattaa aaatggtact actgctgcaa
     4681 aaagtgctgc ttctactgtc atttgattaa aatagcacat aaatactgtt cccataaaat
     4741 atataatagg cattccaaca aaaattgtta ttagtatata tctcttaata tcattatttc
     4801 gtccttttaa taaactaata attagtgctg caaacaaaaa cccaaaataa aaaccacctg
     4861 ttgggcttaa taactttcca ataccagatg tacctccacc aaatactgga atcccaatta
     4921 aacctatcat tatatataca ccaactgtac taaatgcttg tcttggtgtt aaaatcaaag
     4981 ctattaaatt tatcattatt gtttgtgctg ttactcctgc tggagtaaat ggcaatggta
     5041 tatatatgta agatgatata cacaataatg ctacacatat tgacatttta gttaaatctt
     5101 gaatatttac tttagtattt ttcattttta taattccctt catatgtctt atttcattta
     5161 gtttatatgt acatatacaa agcttctatt aaagctttgt tttagtataa aataaagacg
     5221 tttttttgtc aactattata agcatttagg tttacattta atttataagt aaactttata
     5281 ctgttacttt atattttaat agtcatttat aaaactttgc ttaaaaacag ctctatttag
     5341 actatacttg taaattataa tatgatatat ttttatataa gattttattt tatataaaaa
     5401 atagtaacaa atagtttata cacaagatat ttaaaaggaa gtgatgatat gaaagttaat
     5461 gaaaataata taaataatat agatgaagag ttagatgaac ttagtaggaa agtttactta
     5521 gagtcaccag atttttggat aagtatttct gacaaaataa tagataaagt atttgatgaa
     5581 atgttattat tttttgcagt taaatataac tatttcaata tagtatgctt tgctattgaa
     5641 aacaattatc tggatttaaa catgccttca aaaaacaaaa aatacactaa tataatggag
     5701 catttgttag atacatcaaa acagaatgaa gataaaaaaa tttataatta tcttctaagc
     5761 ttaaataaag gtaataacct agatgaaaga ccaattttag atgaattaaa ctgtaatatt
     5821 agtagtgata cttttgaaaa aaaagatata tatcttccaa agtacttatg tccaagttgt
     5881 aattctaata tatttgatac aggttataaa gtatcaaatg acataacata taaattttct
     5941 tctaaagaag ctgaacctat tgaaatgtgt agtgaagttt cttctatcag atgttgtaat
     6001 tgtgatgaat tattagaaga tattacactt gataaactat ataacctatg caaaattcaa
     6061 aactgtaata attgtggttc taatttaact aaggtaggaa ttattgcaaa gaaaaaaatg
     6121 aactttgatg agaatactga aaaatttaaa gatgtctcaa catcttactg ttgtggaaat
     6181 tgtgactctg aaataaactt atctcaaaga gaacatttta agatttaaat atttataggc
     6241 taaagtaata agattacatt attagatact gtataagttt tttaaatctg taaaaataaa
     6301 tacacttata agaattaaaa ttgctatgaa actagttctt gatgaactaa tttcatggca
     6361 attttctata atctaataat tattaaattt taacaaacct ttattagcat tccataatta
     6421 tttaaaattc tttcaaatac cctatagttt ataggtgaaa gtatctttaa tattatatca
     6481 aacttattat ctttaaatag taaatttgtt aaatctgaaa tacaccatac aattttattt
     6541 tcctcttttg tagctatatc aattctgatt aacttacatc tataataaat atctttatct
     6601 tcatatagtc tattttaaaa attactctta aaaaatcaaa tggcaaataa attaattatc
     6661 cttttaatag aatgtaatca tattatttac tatattccat tatgtactct ttaaatcctg
     6721 aatcttcatt tacttgttct tttactatat taaaaccttt tttattataa aacacaactg
     6781 cttttttatt atctttatat actgctaagc ttagactttt atatttttta gttgcataat
     6841 ctaaaagttt acctccgata cctagatttt ggtatttggg ctttataaat aaagctccta
     6901 taaagctttt atctattatg cttataaatc cttttatttc atctccatca tcatatacaa
     6961 atgtatctga tataggtata tattcgtttt taacagtatt atagttattt tgccagtatt
     7021 ctttacttat aaagtcatgt gctttgattg tacttttttc ccatatttcc atgattttat
     7081 ttatatcttt attgtttaat ttctttatca taaattttat ttcacctcat ttttgtattg
     7141 attttataat gtttataggt aagtttattt tatttagata tgatttagtt aatataaggt
     7201 ggatgtttta gtatatgcta ttgttgattc tacaatttta tatactgctt tattaatata
     7261 aaataagttt ctaaatactc gttgatattg ctaatattct acttatctac cacttagtta
     7321 atataaaaca atgatactgt aatatctaaa gatgttacat tggcaaattt acataccact
     7381 tagttaatat aaaaccatct tcagtatcat atgctgaaat attatcaaga tttacatacc
     7441 acttagttaa tataaaacgg caatcatgtc aagtacttct aatataaaaa agttctattt
     7501 acataccact tagttaatat aaaaccttac atggaaaacg aaacatattt aatttgttct
     7561 gaatttacat accacttagt taatataaaa caaatgaagc attgagttta aatagcgata
     7621 ttagaaaatt tacataccac ttagttaata taaaacttca atgaactagg gtttaaaata
     7681 cattctagcc cgaatttaca taccacttag ttaatataaa actttaaaat tccggacaaa
     7741 caacgctaaa tcaaaagaat ttacatacca cttagttaat ataaaactaa tagaattata
     7801 gcatcaacta atcgtaaaat atttatttac ataccactta gttaatataa aacttgcggt
     7861 aagactgttt gttacaggga tggcagagtc atttacatac cacttagtta atataaaact
     7921 caactctcct tgatagattt agcctatctt gcgatattta cataccactt agttaatata
     7981 aaacgaacaa atttaatgga agcaataaaa agtaatgacg atttacatac cacttagtta
     8041 atataaaacg gaggaactaa atttagctta ctttgataaa gaaagattta cataccactt
     8101 agttaatata aaactcaata tcttttctta ttagtttcgc aaattcttca tatttacata
     8161 ccacttagtt aatataaaac gaaggcaaaa actaatgact aataaagaga aaataaaatt
     8221 tacataccac ttagttaata taaaacatat ttaaagcaag tactttttta agaaaactta
     8281 atttacatac cacttagtta atataaaaca tggctaagag atacagataa aaatataaat
     8341 gaatggtatt tacataccac ttagttaata taaaactatt acgagaaaaa tttaaaaacg
     8401 ac
//
LOCUS       DAEPKC010000132         8035 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.133, whole genome shotgun sequence.
ACCESSION   DAEPKC010000132 DAEPKC010000000
VERSION     DAEPKC010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8035)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8035)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8035
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.133"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..537
                     /locus_tag="KR294_003386"
     CDS             <1..537
                     /locus_tag="KR294_003386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FliS"
                     /protein_id="HBH0241434.1"
                     /translation="NHLCKEDLLSISIEKGGSSVLVDGYLISGLMTKEEIEFCIGYGF
                     LLQISDDLQDIKEDLKYNHKTIITEMSKEGTLDKVVNKLINFTIELIDSFKINNKNKS
                     VITMIKNDCLMLILFSVVYNAEFFSVGYIKEVEKFIPYTIDYSLEIEEKIKEKFKNID
                     VLNNENEYKEMIDIICAE"
     gene            complement(690..1751)
                     /gene="ytvI"
                     /locus_tag="KR294_003387"
     CDS             complement(690..1751)
                     /gene="ytvI"
                     /locus_tag="KR294_003387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation integral membrane protein YtvI"
                     /protein_id="HBH0241435.1"
                     /translation="MDIQKQKNFIIKFTYVVLITSIVYIVLKFLLPLLMPFVISFIIA
                     SILRPIIRLITNNTNLNRTLISIVILLIFYGLCIFLLVSFGVKIFASVSDVFFRLPEI
                     YKSSIQPTLNTLFSKIDASTPNVNLALILGWDNISQSMMSLVASISTNALNAIASIAS
                     KTPAFMLKLIITLIASFFFTFDYQKIVNFILKQFPEKSQFMIINIKNSSINALLKLLK
                     AYAILLSVTFIELLIGLTILKVENAFTISVIIALVDILPVLGTGSILTPWMIISLING
                     NINLAIGLLILYIIITVVRQILEPKVVGHQIGLYPLITLMCMFVGAQLFGIAGLFGFP
                     IAATIIKNLHDNGIITAFK"
     gene            2025..2765
                     /locus_tag="KR294_003388"
     CDS             2025..2765
                     /locus_tag="KR294_003388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein phosphatase"
                     /protein_id="HBH0241436.1"
                     /translation="MKNFRDLGGNKTEDGRTVKKGLFYRSAKLSNLSENDIKILKELN
                     IKYIFDYRSDEEARKHPSTIISNIKNIRIPAMRELEESGGSFGSIEDMIDGLFEKDGA
                     FNMLNNSYYNLPINNPSYKKLVELIRDYSNLPILNHCTAGKDRTGVGSAIILMILGVS
                     RENIMKDYLKSNDFADKEIERFIEYKPKFKDIPKENLKYIFGVNEEYMKTAFRRIDEE
                     YISVEAYLYGEFNLNKEEIRKLRNQYLE"
     gene            2777..4555
                     /locus_tag="KR294_003389"
     CDS             2777..4555
                     /locus_tag="KR294_003389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBH0241437.1"
                     /translation="MSLNITARQINIIKILLNSKDTISGIALSQEIGCSSKTIQNEIK
                     DINKQLRNGKILSIRGVGYKLEGSFDEVNLNSNLYDDVDRVEYIIRKILTLSNEEKNT
                     IKLEDLADSMYVSVSTVKNDLKEVKRMLEKYSISVKSKHKQGICVLESEDKILNCIVD
                     LSNKRDNQLSLNDFLNDDIKERKLLIKKLLLDILNENGLVLTDIEFKSVLNNILVMLS
                     RHKYNEKEFIENYIENYRSKRSSILENEQNKEIIINSIKTFCKNLKLATSIDISNDKV
                     FEEFLYKHISSLCKKIKLGINQSPIMAQDIKIKYPFAFELANIAKKTIEKDLKIEINE
                     DEVANIALHIGGAVERASYNNKDKVFKTIIVCTSGIGTSMLIKAKLENIFKEKLEILK
                     IIPSYLVEYIKVIDVDFVISTVPIEVGDVPVINISPILSEKEIRLIEKYIETGNIYLD
                     LDIKSLFDSELFFTDLVFKRKEEVIDFMASKLVQKGYIDEDMKKSYFEREKIATTEIG
                     NMVTIPHGAIGKIFDNKIAIGILKKPISWEISDVRLIIMLALDKDKILDYEVIFSKIY
                     KRVDSIAKVISICENSSFEKFVNLFN"
     gene            4722..5639
                     /gene="pfkB"
                     /locus_tag="KR294_003390"
     CDS             4722..5639
                     /gene="pfkB"
                     /locus_tag="KR294_003390"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HBH0241438.1"
                     /translation="MIYTVTLNPSIDYIVKLDELKTGSTNRVKEEYVYPGGKGINVSR
                     ILKELGNDNTSLGFISGFTGEYIIRTLEEKELKTDFIKIKSGFSRINVKIKALKETEI
                     NGQGPNIDDEDIDTLYKKLDKLNQDDILILAGSIPSTLDEKLYENIMARLEKKNIKVV
                     VDATKNLLLNVLKYKPFLIKPNNDELEELFGVKLNSIEDMVKYARRLKEMGAINVLVS
                     MGKDGALLITEEDEVLISDVPKGKVKNSVGAGDSMVAGFISGYLNTGKYDYALKLGAA
                     SGSATAFSYDLAKREYIDKLVNEISVKKF"
     gene            5676..7595
                     /locus_tag="KR294_003391"
     CDS             5676..7595
                     /locus_tag="KR294_003391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH0241439.1"
                     /translation="MKIIDLLDEKSIKLNLNSKTKSEAIEELVDLVANSGNLNDKENY
                     KKAILAREEMSTTGIGEGVAIPHAKNSSVTKACIAAAVSKEGIDYESFDGSLSNLFFM
                     IAAPDGANNTHLEVLSRLSTILMDEDFRNKLINSSSEKEFKEIIDKKEREKFSEEYQD
                     EKVAEKNIIDTKENDANKYPKVLAVTACPTGIAHTFMAAESLNKMAENKGVSIKVETN
                     GSAGVKNKLTKDEIENATCIIVAADKNVEMARFNGKKVIKTKVADGIHKAEELIDKAV
                     NGDAPIYHGGDGSHNESNEESESGFRKVYKHLMNGVSNMLPFVIGGGILIAIAFLLDD
                     YTINPSNFGSNTPIAAFFKGIGDKAFGFMLPVLAGYIAYSISDRPAFVVGFVGGALAG
                     DGGSGFLGALLAGFIAGYLVEGLKKIFSVLPASLEGIKPVLLYPLLGTLLMGIIMTFL
                     VIPPVTAINNAMVGFLNGLGGTSKIVLGLVLGGMMAVDMGGPVNKAAYVFGVASLESG
                     QFEIMAAVMAGGMVPPLAIALATTFFKNRFTKEERDSGKVNYVMGLSFVTEGAIPFAA
                     GDPLHVIPACVGGSAVAGALSMLFNAALRAPHGGVFVIPVVTHPFAYILAIAVGALVG
                     MMLLALLKKPLNQEV"
BASE COUNT         3294 a          754 c         1375 g         2612 t
ORIGIN      
        1 aatcatttgt gtaaagaaga tttattatcc atttctattg aaaaaggagg ttcatccgtt
       61 ttagtagatg gatatttaat aagtggattg atgacaaagg aagaaataga gttttgtata
      121 ggatatggat ttttattaca aatatctgat gatttacaag atataaaaga agatttaaaa
      181 tacaaccata aaactattat tacagagatg tcaaaagagg gtactttaga taaagttgta
      241 aataaactaa taaattttac tattgagtta atagatagtt ttaaaattaa taataaaaat
      301 aaatctgtaa taactatgat aaagaatgat tgcttaatgt taattttatt ttctgtagtt
      361 tataatgctg aatttttttc tgtaggatat ataaaagaag tagagaaatt tattccatat
      421 acaatagatt attcattaga gattgaagaa aaaataaaag aaaaatttaa aaatatagat
      481 gttttaaata atgaaaatga atataaagaa atgattgata ttatttgtgc agagtagaaa
      541 aaaagggagt gtcttagaat agacttttta gtttatgagg cactcttttt gtataaaatc
      601 aaatgtattt tcatcatttt aataattaaa aagagcttat ccctatttga gaaagccctt
      661 tttaatttaa taaaaatgtc aaggttaaac tatttaaatg cagtaataat cccattatca
      721 tgtaagtttt ttatgattgt agctgcgata gggaatccaa ataatccagc tattccaaat
      781 agttgagctc caacaaacat acacattaat gttattaaag gatataggcc aatttggtgt
      841 cctactacct ttggttctaa tatttgtcta acaacggtta taattatgta tagtattaaa
      901 agtcctattg ctaaattaat atttccatta atgagtgaga taatcatcca aggtgtcaaa
      961 atacttcctg tacccaagac tggcaaaata tcaacaagtg ctatgatgac agatatagta
     1021 aatgcatttt caacctttag gatagtaagt ccaataagta gttctatgaa tgtcactgat
     1081 agtagtattg cataggcttt tagtagtttt aaaagagcat taatactgct attttttata
     1141 tttattatca taaattgact tttttctgga aattgtttta agataaagtt tactattttt
     1201 tgatagtcaa aagtaaagaa aaaagaagca attaaagtaa taataagttt taacataaat
     1261 gcaggtgttt tacttgcaat actagcaata gcattgagtg catttgttga aatagaagct
     1321 actaaagaca tcatagattg acttatatta tcccaaccaa gtattaatgc taggttaaca
     1381 ttaggtgtac tagcatctat ctttgaaaat aaagtattta gcgttggttg tatacttgat
     1441 ttatatattt caggaagtct aaaaaataca tcacttacac ttgcaaatat cttcacacca
     1501 aagctaacta ataaaaatat acacaaccca taaaaaatta aaagtattac tatagaaata
     1561 agtgtacgat ttaaatttgt attatttgta ataagtctta taataggtct taagatggat
     1621 gcaatgataa aactgattac aaaaggcatt aataatggca ataagaattt taatacaata
     1681 tatacaatac ttgttattaa aactacatat gtaaatttaa ttataaaatt cttttgcttt
     1741 tgaatatcca taatataaaa cctccaatgt atttgatatt attctaaata tggtcttttt
     1801 tacagaaaat atactactgt atattgatta taaactataa agcttatgta aagtaaataa
     1861 attatgtaaa atttaggtta attttgtata aagagatact tttatatttt acaattaata
     1921 accaaatact aaaaaatatt ttaaataaag aacttaaaat tgtgataaaa ttaatttata
     1981 gatattaaaa aaagtataat atatggtttt taagaggtgc taagatgaaa aattttagag
     2041 atttaggtgg gaacaaaact gaggatggca gaactgtaaa gaagggatta ttttataggt
     2101 ctgcaaaatt atcaaatcta agtgaaaatg atataaagat tttaaaagag ttaaatatta
     2161 aatatatatt tgattataga agtgatgaag aagctcgtaa acatccatca acaataatat
     2221 caaatataaa aaatataaga ataccagcaa tgagagagct agaagaatca ggaggaagtt
     2281 ttggttctat tgaagatatg attgatggat tgtttgaaaa agatggtgca tttaatatgt
     2341 taaataatag ttactataat ttgcctataa ataatccgtc atataaaaaa ttagtagaac
     2401 ttataagaga ctattctaat ttaccaatat taaatcattg tacagctggt aaggatagaa
     2461 ctggtgtggg gagtgctata attcttatga ttttaggggt atcgagagag aatataatga
     2521 aagattatct aaaaagtaat gattttgcag ataaagagat agaaagattt atagaatata
     2581 agcctaaatt taaggacatt ccaaaagaaa atttgaaata tatatttggt gtaaatgaag
     2641 agtatatgaa aactgcattt agaagaattg atgaagaata cattagtgta gaagcatatt
     2701 tatatggaga atttaattta aataaagaag aaataagaaa attaagaaat caatatctag
     2761 agtaaaaggt gagtttatga gtttaaatat aacagcaaga cagataaata taataaaaat
     2821 attgttaaat tcaaaagata caattagtgg tattgcctta agtcaagaga taggatgttc
     2881 ttcaaaaact atacaaaatg aaataaagga tattaataaa caacttagaa atggtaaaat
     2941 tttgtcaata agaggagttg gttataaact agaaggaagt tttgatgagg taaatctaaa
     3001 tagcaatctc tatgatgatg tagatagagt agaatatata atcagaaaaa tattaacctt
     3061 aagtaatgaa gaaaaaaata ctataaaact tgaagattta gccgattcta tgtatgtaag
     3121 tgtttcaaca gtaaaaaatg atttaaaaga agtaaaaaga atgttggaaa agtattcaat
     3181 atcagttaaa tctaagcata aacaaggtat atgtgtttta gaaagtgaag ataagatatt
     3241 aaattgtata gttgacttaa gcaataagag agataatcaa ttgagtttaa atgatttttt
     3301 aaatgatgat ataaaggaaa gaaaactatt aataaaaaaa ttattattag acatattaaa
     3361 tgaaaatgga ttagtattaa ctgatataga atttaagagt gtgttaaata atatattagt
     3421 tatgttaagc agacataagt ataatgaaaa agaatttata gagaattata tagaaaatta
     3481 taggagcaaa agaagctcaa ttttagaaaa tgaacaaaac aaagaaatta taataaattc
     3541 aataaaaaca ttttgtaaaa atttaaaatt agctacatca atagatataa gtaatgataa
     3601 ggtatttgaa gagtttttat ataagcatat tagtagttta tgtaaaaaaa taaagttagg
     3661 tataaatcaa tcacctataa tggctcaaga tataaaaata aaatatccat ttgcttttga
     3721 actagctaat atagctaaaa agacaataga aaaagatttg aagatagaaa ttaatgaaga
     3781 tgaagttgca aacatagctc tacatatagg aggagcagtt gaaagagcat cttataataa
     3841 taaagataag gttttcaaaa ctataatagt ttgtacttca ggcataggca catcaatgtt
     3901 aataaaagct aaattagaga atatatttaa ggaaaaatta gaaatactaa agattattcc
     3961 ttcatactta gttgaatata taaaagttat agatgttgat tttgtaatat ctactgttcc
     4021 tattgaagta ggagatgtgc cagtaataaa tatatctcca attttaagtg agaaagaaat
     4081 tagattaatt gaaaaatata tagaaacagg aaatatatac ctagatttag atataaaaag
     4141 cctgtttgat agtgaattgt tttttactga tttggtgttt aaaaggaaag aagaagttat
     4201 agattttatg gcaagtaaac ttgtacaaaa gggctatata gatgaggata tgaaaaaatc
     4261 ttactttgag agagaaaaaa tagcaacaac agaaataggg aatatggtaa ctataccaca
     4321 tggagctatt ggaaaaattt ttgataataa aatagcaatt ggtatattaa agaagcctat
     4381 ttcttgggaa atatcagatg ttcgtttaat aataatgtta gcccttgata aagataaaat
     4441 attagattat gaagtaatat tttcaaaaat atataaaaga gtagattcta tagcaaaagt
     4501 tataagtata tgtgaaaata gtagttttga aaaatttgta aatttattta attagatggg
     4561 tagtattgta tatacacctg taaatttgga taatataaaa ctaaataaga taaaaacgat
     4621 aaatttctct tttaattaag agaaattttt tgactttcaa ggatattaat ataaagttaa
     4681 gatataaaca taaagcaaat aaataaaaaa gaggtggcaa tatgatttat acagtgacat
     4741 taaatccatc aatagattat atagttaagc tagatgagct aaagacagga agtacaaatc
     4801 gtgtaaaaga agaatacgtt tatccaggag gaaaaggtat aaatgtatct cgcatactta
     4861 aggaacttgg aaatgataat acatctttag gttttataag tggttttact ggagaatata
     4921 taataagaac attggaagaa aaagaattga agacagattt tataaagata aaaagtggtt
     4981 tttcaagaat aaatgtaaaa ataaaggcgt taaaggaaac tgagattaat ggacaaggtc
     5041 caaatataga tgatgaagac attgatactt tatataaaaa acttgataag ctaaatcaag
     5101 atgatatttt aatattggca ggaagtatac catctacttt agatgaaaaa ctatacgaaa
     5161 atataatggc tagattagaa aaaaagaata taaaagttgt agtagatgca actaaaaatc
     5221 ttcttcttaa tgttttaaaa tacaaacctt ttctaattaa gcctaataac gacgaattag
     5281 aagaactatt tggtgttaaa ttaaattcaa ttgaagacat ggtaaaatat gctagaaggt
     5341 taaaggaaat gggagctata aatgtcttgg tatcaatggg aaaagatgga gcattgttga
     5401 ttacagagga agatgaagtg cttataagtg atgttccaaa aggaaaagta aaaaattctg
     5461 taggagcagg tgattcaatg gtagcaggat ttatatctgg gtatttgaat actgggaaat
     5521 atgattatgc tcttaaattg ggagcagctt caggtagtgc aactgctttt tcatatgact
     5581 tagccaaaag agaatacatt gataaattgg taaatgaaat atctgtaaag aagttttaaa
     5641 atattaaaaa atatatagaa aggtaattaa tatttatgaa aattatagat ttattagatg
     5701 aaaagtcaat taagttaaat ttaaattcaa aaaccaaatc agaagcaata gaagaattag
     5761 tagatttggt cgcaaatagt ggaaatttaa atgataaaga aaactacaaa aaagcaattt
     5821 tggctcgtga agaaatgagt acaacaggaa ttggagaagg tgtagctata cctcatgcta
     5881 aaaattcttc agttactaaa gcttgtatag cagcagcagt gtcaaaagaa ggtatagatt
     5941 atgaatcgtt tgacggaagt ttatcaaatc tattttttat gatagctgca ccagacggag
     6001 ctaacaatac tcatcttgaa gtattatcaa gattatctac aatacttatg gatgaagact
     6061 ttagaaataa acttataaat tcaagctctg aaaaagaatt taaggaaata atagataaaa
     6121 aggaaagaga aaaattcagt gaagaatatc aagatgagaa agtggctgaa aaaaatataa
     6181 tagatactaa agagaatgat gctaataagt atcctaaggt tttagcagta acagcatgtc
     6241 caactggaat agcacataca tttatggcag ctgaaagttt aaataaaatg gcagaaaaca
     6301 aaggtgtatc aataaaagta gaaactaatg gttcagcagg tgttaaaaat aagcttacaa
     6361 aagatgaaat agaaaatgca acatgtataa tagtggcagc agataaaaat gttgagatgg
     6421 ctagatttaa tggcaaaaaa gtcataaaaa ctaaggtggc tgatggtata cacaaagcgg
     6481 aagaacttat agacaaggct gtaaatggag atgctccaat ttaccatgga ggagatggaa
     6541 gtcacaacga atcaaatgaa gaaagtgaaa gtggatttag aaaagtatac aaacacttaa
     6601 tgaatggtgt atctaatatg ttaccatttg ttattggtgg agggatactt atagcgatag
     6661 cctttttact tgatgattat actattaacc cttcaaactt tggttcaaat acacctatag
     6721 cagcattttt taaaggaata ggagataaag cttttggatt tatgttacct gtacttgctg
     6781 gatatatagc atactctata tctgatagac cagcgtttgt tgtaggattt gtaggaggtg
     6841 ctctagcagg tgatggtggt tcaggctttt taggtgcact acttgcaggt tttatagcag
     6901 gttatttagt agaagggctt aagaaaatat ttagtgtact accagcttca ttggaaggaa
     6961 taaaaccagt attgttatat cctttacttg gaacactttt gatgggaatt ataatgacat
     7021 ttttagtaat acctccagtt acagcaatta ataatgcaat ggttggattt ttaaatggtt
     7081 taggtggaac ttcaaaaata gttttaggat tagtattagg tggaatgatg gctgtggata
     7141 tgggtggacc tgtaaataaa gcagcatatg tatttggagt tgcatcactt gaatcagggc
     7201 agtttgaaat aatggcagca gtaatggctg gtggtatggt tccgccactt gctatagctc
     7261 ttgcaactac attttttaag aatagattta ctaaagaaga aagagattct ggtaaagtta
     7321 attatgtaat gggattatca tttgttactg aaggagctat accttttgca gctggagacc
     7381 cacttcatgt tataccagct tgtgttggag gttcagcagt ggcaggagca cttagtatgt
     7441 tgttcaacgc agctcttcgt gcacctcatg gaggagtatt tgttatacca gtggttaccc
     7501 atccatttgc atatatatta gctatagctg taggtgcttt ggttggaatg atgcttttag
     7561 cattacttaa aaaaccatta aatcaagaag tatagcaatt aaaggatatt caagaactta
     7621 aaatatgatg ttttataaaa attaatatat tgctgaatta ttttaaaata aggattttat
     7681 gaggctgtta tataacgatt tgtaattgtt atcttgacag tcttttattt ttatataagt
     7741 aaaataagtg tgttttgctt tatttgtatt taaattgttt ttaagttaga atataaagaa
     7801 aattatatat tattttaata ttcactcgaa ctagaaaata atatttgttg tattttttgt
     7861 atataaaaat atattgtaat attaaaaaaa taatagtaaa ctgattgcat aaaaatgatt
     7921 tttatataaa ttttaaacag aagaataaat ttctaacgaa attggatatt tcttctgtaa
     7981 atacatattc aaaaaaagaa ttataagagt ttagtcagca gtcgtgtaag taata
//
LOCUS       DAEPKC010000133         7893 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.134, whole genome shotgun sequence.
ACCESSION   DAEPKC010000133 DAEPKC010000000
VERSION     DAEPKC010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7893)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7893)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7893
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.134"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(<1..742)
                     /locus_tag="KR294_003392"
     CDS             complement(<1..742)
                     /locus_tag="KR294_003392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:glutamate symporter"
                     /protein_id="HBH0241440.1"
                     /translation="MITLSFDIVQTLTLSIFFFLIGNLLKNKVNFLNNFCIPAPVIGG
                     LLFCFLNLFFKYFNIADISISGNLMPNFITFFFTTIGLEISINLIKKGGSVLFRYWIL
                     CGVLAFCQNILAITISKIIKLEPLLGLMCGNVSMEGGHGYSAAFGLTIENLGIEGAVG
                     VGLSAATIGLIMGGILGCPVAKFLINKYKLKPSSNIDLSIPRYNRNLKRFGSKFFRNK
                     NRIKNNNFSETITPSVFLEQVLLIFICIN"
     gene            1002..1991
                     /locus_tag="KR294_003393"
     CDS             1002..1991
                     /locus_tag="KR294_003393"
                     /EC_number="3.5.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HBH0241441.1"
                     /translation="MFENLPKIDLHCHLDGSVRVETMLDIAIKEKIDLPSNNMDEIKK
                     LAKVSFNCTSLDEYLEKFDLPLKVMQSKENLKRITFELLEDASRENVKYIEIRFAPLL
                     HTQKGMSVKNIIEGIIEGIREAESIYDIKGNLILGCMRTMTSKEALLVIEEGKSFVNK
                     GVVAVDLCGPEKEGFCKEYKDVFKLAREYGYKVTIHAGEAASGENVLDAINILKADRI
                     GHGVKIKDHKKAYNLVKDKKILLELCPTSNVQTKTVDSYEAHPFYTFYKDNLHVSINT
                     DNRTVSDINLSSELNVIFDTFKLGLEDYKIIYRNAVEASFADKETKEYLNSLI"
     gene            2063..2803
                     /locus_tag="KR294_003394"
     CDS             2063..2803
                     /locus_tag="KR294_003394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EcsC family protein"
                     /protein_id="HBH0241442.1"
                     /translation="MKDYEDVVYIKLVKKELEEWKKNILKKPSIFDKASKGIQNKFNG
                     VLPDKYHEIITSSIKVMTKTVLFGYKYATKPPLRNMSLEEREKLVLEKAKTYKTTAMI
                     EGAGTGAGGILLGLSDFPLLLGIKVKFLYDVASIYGYDVKDYRERIYILNILQLAFSS
                     QQHINKTFKLMNNWDEYVNSLPEDINDFDWRTFQQEYRDYLDLAKFLQLMPGIGAFVG
                     FYVNGKLIDKLCETAVSAYRLRIRELKL"
     gene            3019..4170
                     /locus_tag="KR294_003395"
     CDS             3019..4170
                     /locus_tag="KR294_003395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyacyl-CoA dehydratase"
                     /protein_id="HBH0241443.1"
                     /translation="MTNLPKQFDSFNEARQKGFINAKELKESGKKMVGVFCTFTPVEI
                     PMAAGATVVGVCGVSEEPIPDAERVLPRNLCPLIKSSYGHAITDTCPYFYFSDLLIGE
                     TTCDGKKKMYEELAKVKPTYVMHLPNTSKGEFAYKLWKDEMIRLKEEVEKSLGVTITE
                     EDIRTAIKDKNEERELLKEFYALGKLQPSALTGLELHNVLYQAGFKFDRAELKHSLRK
                     VIDDMKERYEKGECPVQKDKPRILITGSPIGGISEKIVKTLEDAGASVVAYELCGAIR
                     SNDLLVDEEIEDVYDALTQKYINIGCSCMMNNDNRIELLDRIIDEYNVDAVIDVVLQA
                     CHTFNIESYRIREFVTKEKNKPFMSLETDYSKSDTEQLRTRFEAFVEML"
     gene            4195..4950
                     /locus_tag="KR294_003396"
     CDS             4195..4950
                     /locus_tag="KR294_003396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyglutaryl-CoA dehydratase"
                     /protein_id="HBH0241444.1"
                     /translation="MFSIGVDSGSVATKGVLFDGEKIIKKIIIPTGWSPKSTSKQVYE
                     LLSSEIDKKDIKKVVGTGYGRGVMDFADKKVTEITCHTRGIYFLNKNIRTILDVGGQD
                     SKVINLDRDGNVFNFIMNDKCAAGTGRFLEITSNLLGSDIESIDTLAKGYEPVNISSM
                     CTVFAESEIVSLLAQNISTGEVAAGILKSIANKSTSMLARGEVIDEVAFTGGLAKSKE
                     LVKMIEEILGKKIFIAEDTQIIGALGAAVIGFR"
     gene            5142..7529
                     /locus_tag="KR294_003397"
     CDS             5142..7529
                     /locus_tag="KR294_003397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding cysteine protease Cwp13"
                     /protein_id="HBH0241445.1"
                     /translation="MKKFTSKKVTRFVALFLISILVMSTIPVSADNSNTLNQIKKAEY
                     SETYKQYLNDAKNGCTEKYNGIIPNPYQLEGTQIQSKGRTAPTSYDPRKLGLMTSIKN
                     QEDLGICWDFAAMATLESFLKLNNYGDYDLSEEHLRWWASDGEYGWSVNDMNGALNYE
                     AMGYLTSWSGPKLEKDIPYNGRVSKAQGAKKPTNMNTAPTVFNVTDAVCVSNDINSTK
                     NAILQYGAVTSGYYEDIKYQSDDQNSYYCPTKSFNTNHAISIVGWDDNYSKDNFNANI
                     RPSKNGAWLIKNSWGDYNSEGGYFWISYEDKTLMSDIDNFSIKGGKKPNDDEKMYQHD
                     YASIVPLISKKITAANVFDFNRGDETLKSVMFLTESIGAKYEVYYAPVVNGIPQENNM
                     KKLKEGTAQYSGYITVPIDSFDIPEGKGAIVVSIEGKNGESTIGSESNVPGYDTFKAK
                     ANLGESYIIDNTGKFFDINRDSNFYPCNFTIKAVTEKSSGESIPNESLIGSDRYETAI
                     KVSQNGFNSSENVVLVNGSSIVDALAATPFTSAINSPILLTQKEALNSKTKAEIQRLG
                     AKKVYLIGGENSISKEIEQQLKSLNISIERISGSDRYKTSLLLAQKLNGIKNVSQIAV
                     VNGVKGLADAISVGAAAAENNIPIILANEKSELQGADEFLNSLNIEKSYIIGGTASLS
                     NNLESKLKNPTRLSGSSRDETNSKIIDNFYKKDTLKNAFVVKNGIKNQNDLIDGLAVG
                     PLGAKTGSPVILVGDKLADSQKEVLKNKTLEKVTQVGGGANKNAFKELVKLKSAK"
BASE COUNT         3169 a          847 c         1385 g         2492 t
ORIGIN      
        1 tatttataca aataaatatg agaagaacct gttccaaaaa tacagatggt gttattgttt
       61 cggagaagtt attatttttt atcctattct tatttctaaa aaatttactt ccaaatctct
      121 ttagatttct attatatcta ggaatcgaca agtctatatt tgatgatggt tttaatttat
      181 atttatttat tagaaattta gctacaggac atcccaatat accacccata ataagtccta
      241 ttgttgcagc agataatcca accccaactg ctccttctat accgagattt tctattgtaa
      301 gtccaaatgc agcagaataa ccatgaccac cttccataga tacatttcca cacataagcc
      361 ctaaaagagg ttcaagtttt ataatctttg atattgtaat agctaatata ttttgacaaa
      421 atgccaatac tccacacaaa atccaatatc taaataatac actaccacct ttctttataa
      481 gatttatgct tatttcaagt cctatagttg taaaaaagaa ggttatgaaa tttggcatta
      541 aatttccact tatagatata tctgctatat taaaatattt aaaaaataaa tttagaaaac
      601 aaaataatag acctcctatt actggtgcag gtatacagaa attatttaaa aagttaactt
      661 tattcttcaa taaattacca attaaaaaga agaatataga tagtgtcaag gtttgcacta
      721 tatcaaaact taaggtaatc aaaataagtc ctcctttgta attcaaagtt ttaattatat
      781 aacttaaatt cttatgtatt gaaattttat tatcaaatgt atattaataa atgtatatta
      841 aaaagaatca gtagatataa ttagatagtc ataaattaaa ttaaaatatt ttaatgagat
      901 atgacttttt tagaattaaa aaccgtagta tattgatata atagaaataa gacttaaaaa
      961 tctgttgata gtattattta taagtacagt aggaggataa aatgtttgaa aatttaccta
     1021 agatagattt acattgccac ttagatggaa gtgttagagt agaaaccatg cttgatatag
     1081 ctattaaaga gaaaatagat ttaccttcaa ataatatgga tgaaataaaa aaattagcaa
     1141 aggtttcttt taattgtact tcactagatg aatatttaga aaaatttgat ttacccttaa
     1201 aagtaatgca atctaaggaa aatttaaaaa gaattacttt tgaacttttg gaagatgcaa
     1261 gtagagaaaa tgtaaaatat attgaaatta gatttgcacc attacttcac acccaaaaag
     1321 gtatgagtgt taaaaatata attgagggta taattgaagg aattagagaa gctgaaagta
     1381 tttatgatat aaaaggcaat ttaatattag gttgtatgag aacaatgacc tcaaaagagg
     1441 cattattagt aattgaagaa gggaaatcat ttgtaaataa aggtgttgta gcagtagact
     1501 tgtgtggtcc agagaaagag ggattttgta aggaatataa agatgttttt aaattagcaa
     1561 gagaatatgg atataaagtt acaatacatg caggagaagc tgcaagtgga gaaaatgtat
     1621 tggatgctat aaatatttta aaggcggata ggattggtca tggggtaaaa attaaagacc
     1681 ataaaaaggc gtataattta gttaaagata aaaaaatatt gcttgaatta tgtccaacta
     1741 gtaatgtaca aactaagaca gtagattctt atgaagcaca tccattttat actttttata
     1801 aagataattt acatgtaagt ataaatactg ataatagaac tgtatcagat ataaatttaa
     1861 gttcagaact aaatgttata tttgatactt ttaaactagg attagaagac tataaaataa
     1921 tttatagaaa tgcagtagaa gctagttttg cagataaaga aactaaagag tatttgaata
     1981 gtttaattta atagataaaa atatttaaac tttaaattaa gctattaaat tgataaaaat
     2041 acattgtatt aggagaaaaa atgtgaaaga ttatgaagat gttgtttata ttaaactagt
     2101 caaaaaagaa cttgaagaat ggaagaaaaa tatattaaag aaaccttcta tatttgacaa
     2161 agcatcaaag ggtatacaga ataaatttaa tggagtattg ccagataaat atcatgaaat
     2221 aattacttct tctataaaag taatgacaaa aaccgtactg tttggatata aatatgctac
     2281 aaagccacca cttagaaata tgtcattaga agaaagagaa aaattagttt tagaaaaagc
     2341 taaaacttac aagactacag caatgattga aggggcagga acaggggcag gaggaatcct
     2401 cttaggttta tctgattttc ctttgctttt aggtattaaa gtgaaatttt tatatgatgt
     2461 agcttcaata tatggatatg atgttaaaga ttatagagaa aggatttata tattaaatat
     2521 attacagttg gctttttcta gtcaacagca tataaacaaa acttttaaat tgatgaataa
     2581 ctgggatgaa tatgtaaata gtctaccaga agacatcaat gattttgatt ggagaacatt
     2641 tcaacaagag tatagggatt atttagattt agctaagttt ttacaactaa tgcctggaat
     2701 aggagcattt gtaggatttt atgtgaatgg aaaattaatt gataaattat gtgaaactgc
     2761 tgtgtctgct tatagattga ggattcgaga gcttaagtta taagaaaaat tataacataa
     2821 aaaattagtt atacaatata tctatatgta tctaattttg cattgataaa aacaattatg
     2881 gataaaaggt aaagcatgat agaatctaat gtagaggttt gtattttaat ggaaaaattt
     2941 agtttttatt gcttaagata caaattgaat tacgaagaga ttgaattatg aagagaagta
     3001 attgggagga atattttcat gacaaatttg ccaaaacaat ttgatagctt caatgaagct
     3061 agacaaaaag gatttataaa tgcaaaggaa cttaaggaaa gtgggaaaaa gatggttgga
     3121 gttttctgta catttactcc agttgaaatt ccaatggcag ctggagcaac tgtagtaggt
     3181 gtatgcggcg ttagtgaaga gccaatacct gatgcagaaa gggtgcttcc aagaaatctt
     3241 tgtcctttaa ttaaatcaag ctatggacat gcaataacag atacctgtcc ttatttctat
     3301 ttttctgatt tgttgatagg agaaaccact tgtgatggta agaaaaaaat gtatgaagaa
     3361 cttgcaaaag ttaagccaac atatgtaatg catttgccaa atacttcaaa aggagaattt
     3421 gcctataaac tttggaaaga tgaaatgata agattaaaag aagaggttga gaaatcttta
     3481 ggtgtaacta taactgaaga agatataaga actgctataa aagataaaaa tgaagaaaga
     3541 gaacttttaa aagagtttta tgcacttggt aaattacaac catctgcact tacaggcctt
     3601 gagttacata atgttttata tcaagcaggt tttaaatttg accgtgcaga acttaaacat
     3661 tctttaagaa aagttataga tgatatgaaa gaaagatatg aaaaaggtga atgtcctgtt
     3721 caaaaagata agccaagaat attgataaca ggttctccta ttggtggaat aagcgaaaaa
     3781 atagttaaaa ctttagaaga tgcaggggca tcagtcgttg catatgaact ttgtggagct
     3841 attagatcaa acgatttatt ggttgatgaa gaaatagaag atgtatatga tgctttaaca
     3901 caaaaatata taaatatagg ttgttcttgt atgatgaata atgacaatcg tattgaatta
     3961 ttagatagaa taatagatga atataatgta gatgctgtaa tagatgtagt tttacaagca
     4021 tgtcatacat ttaatataga aagttataga ataagagaat ttgttacaaa agaaaaaaat
     4081 aagccattta tgtctcttga aactgattat tcaaaatcag atactgaaca attaagaact
     4141 agatttgaag cgtttgtaga gatgttgtag gaataaataa aagtaggagg aactatgttt
     4201 agtataggag ttgactcagg gtcagtggca acaaagggtg tgctatttga tggtgaaaaa
     4261 attattaaga aaataattat accaactgga tggagcccta aaagtacatc taaacaggtc
     4321 tatgagttgc taagtagtga aattgacaaa aaagatataa aaaaggtggt aggtacaggt
     4381 tatggaaggg gagtaatgga ttttgctgat aagaaagtaa cagaaataac ttgtcatact
     4441 agaggtattt actttttaaa caagaacata aggactattt tagatgtagg tggtcaagat
     4501 agtaaagtta taaatttaga tagagatgga aatgtattta actttataat gaatgataag
     4561 tgtgctgcag gaactggtcg atttttagag attacttcta accttttagg aagcgatatt
     4621 gaaagtatag atacattagc taaaggatat gaaccagtta atatatctag tatgtgtaca
     4681 gtttttgctg agtctgaaat tgtaagtctt ctagctcaaa acatttctac tggagaggta
     4741 gcagcaggga tacttaaatc tattgcaaat aaatccacct caatgttagc aagaggtgag
     4801 gtaatagatg aagttgcatt tactggaggg cttgcaaaaa gtaaagaact agtaaaaatg
     4861 atagaagaaa tactgggtaa aaaaattttt attgcagaag atactcaaat aataggagct
     4921 ttaggagctg ctgtaatagg atttagataa aaacatataa aaagaaaatg agaagctgaa
     4981 tttattataa ataaattcag ttttttattt tattttattt atttataaag gaaaactttg
     5041 gtataattga tttaaatgat tgtatatttg taaatacttg atatttagtc atatataaca
     5101 ttataatttt aaaaattagc tcaaaataag ggggagaaag cgtgaaaaaa tttacttcaa
     5161 aaaaagtaac aaggtttgtt gcgctgtttt taatatctat tttagtaatg tcaacaattc
     5221 ctgtatcagc tgacaatagc aatacattga atcagataaa aaaagcagaa tacagtgaga
     5281 cgtataaaca atatctaaat gatgctaaaa atggatgtac agaaaaatat aatgggatta
     5341 taccaaatcc atatcagttg gaaggtactc aaatccaaag taaaggaaga acagctccaa
     5401 catcttatga ccctagaaaa ttaggtctta tgacatcaat aaaaaatcaa gaggatttag
     5461 gaatctgttg ggattttgct gcaatggcaa ccttagaaag tttcttaaag ttaaataatt
     5521 atggagacta tgatttatca gaagaacact taagatggtg ggcttcagat ggtgaatatg
     5581 gatggtctgt aaatgatatg aatggtgctt taaattatga agctatggga tatttaacat
     5641 cttggtcagg tcctaaatta gaaaaagata tcccatacaa tggtagagta tctaaagcac
     5701 aaggagcaaa aaaaccaact aatatgaata cagcacctac tgtttttaat gtgacagatg
     5761 ctgtgtgtgt aagcaatgac ataaattcta caaaaaatgc tatattacag tatggagctg
     5821 taacatctgg ttattatgaa gatattaaat atcaaagtga tgaccaaaat tcatattatt
     5881 gtccaacaaa aagttttaat acaaatcatg ctatttcaat tgtaggttgg gatgataact
     5941 attctaaaga taattttaat gcaaatatta gaccatcaaa aaatggtgct tggttaataa
     6001 aaaatagctg gggagattat aattctgagg gtggatattt ctggatatct tatgaagaca
     6061 agacacttat gtctgatata gataattttt caatcaaagg tggtaaaaaa ccaaatgatg
     6121 atgagaagat gtatcaacat gactatgcaa gtattgtacc tttaatttca aaaaagataa
     6181 cagctgcaaa tgtatttgat ttcaatagag gcgatgaaac tctaaaatct gtaatgttct
     6241 taactgaaag tataggagct aagtatgaag tatattatgc tccagtagta aatggtatac
     6301 ctcaagaaaa caatatgaaa aaattaaaag aaggtactgc ccaatattca ggatacataa
     6361 cagttccaat tgattctttt gatataccag aaggaaaggg tgcaattgta gtcagtatag
     6421 aggggaaaaa tggagagtca actataggtt ctgagtcaaa tgtaccagga tatgatacat
     6481 ttaaagcaaa agctaattta ggtgaaagtt atatcataga taatactgga aaattctttg
     6541 atataaatag agatagtaac ttctatccgt gtaattttac tataaaagct gttacagaaa
     6601 agtcttctgg tgagagtatc ccaaatgagt ctttaattgg tagtgataga tatgaaactg
     6661 ctatcaaagt tagtcaaaat ggtttcaatt cttcagaaaa tgtagtttta gtaaatggca
     6721 gttcaatagt agatgcattg gcagcaactc cttttacatc tgctataaat tcaccaatat
     6781 tattgacaca aaaagaagct ttaaattcaa aaactaaagc tgagatacag agattaggtg
     6841 ctaagaaagt atacctaata ggtggagaaa attctataag taaagaaatt gaacaacaat
     6901 taaaaagctt aaatatatcg atagagagaa tatcaggaag tgatagatac aagacaagtt
     6961 tattattagc tcaaaagtta aatggtataa aaaatgtatc tcaaatagca gttgtaaatg
     7021 gagtgaaagg attagctgat gcaattagtg taggcgctgc agcagcagaa aataacatac
     7081 caatcatact tgcaaatgaa aagagcgaat tgcaaggagc tgatgaattt ctaaattcat
     7141 taaatataga gaaatcttat attattggag gaacagcatc cctatcaaac aatctagaaa
     7201 gtaagttaaa aaatccaact agattatctg gtagtagtag agacgaaact aattcaaaga
     7261 taatagataa tttttataaa aaagatactt taaaaaatgc atttgtagtt aaaaatggaa
     7321 tcaagaatca aaatgattta atagatggat tggcagttgg tcctttagga gcaaaaactg
     7381 ggtcaccagt aattttagtt ggtgataaat tagctgatag ccaaaaagaa gttcttaaaa
     7441 ataagacttt agaaaaagta actcaagttg gtggaggagc aaataaaaat gcatttaaag
     7501 agttagtaaa attaaaaagt gctaaataga gtacttaagt attaacatat attagtgtgt
     7561 attagtaact tatcttaata aaagctgaaa ataattactt caaattattg ataaataaga
     7621 taatcaatga ttgtaaagtt ttgttttcag ctttaaattt atgtagtata agtttaaaaa
     7681 cataaaaaag ggttacttta tatagaaata tagaaaatct tacattttat atataaataa
     7741 cccatattta attaactttt tatagtgttc taatagatat tattgaactt aatggtaaat
     7801 ataatgtgta agtttcattt aaagttggat tagattcatc tatatatctt gagcaaagtg
     7861 taattgataa gctatctgct tctataattt cac
//
LOCUS       DAEPKC010000134         7840 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.135, whole genome shotgun sequence.
ACCESSION   DAEPKC010000134 DAEPKC010000000
VERSION     DAEPKC010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7840)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7840)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7840
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.135"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(208..1785)
                     /locus_tag="KR294_003398"
     CDS             complement(208..1785)
                     /locus_tag="KR294_003398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp5"
                     /protein_id="HBH0241446.1"
                     /translation="MKAPKTILTILTIALTLSSISIIPSYALTEEKLIGNGRYETAVK
                     ISQKAYSSSSNVVLVNDNSLADALSATPFAKAKGAPILLTESDKLDDRTEKEIKRLGA
                     KDIYLIGGTAVLNKDIENKLKGNGLNVERINGKDRYETSLILANKLKDIKDIKEVAVV
                     NGEKGLSDAVSVGAPAAQNKMPIILSSPKDGVEAFDKFIRDEKVIKAYVIGGTNSVSR
                     AVEKSLPNAERVSGKDRNETNAKVIEKFYTDTNLSNLYVTKDGSKNENQLIDSLAVGV
                     LAAKNESPVVLVGNKLNTKQRDILSTKKLNTITQVGGNGNEEAFDEIISLQEKTVFEA
                     KTVEELTDMINIASPNDIINFKPKENTVNEAFRMVTNKPITVNIKGDCSKTITVDMPN
                     GEVNNYATLVNVIVRNIGEGGFNNHDTITILSVRDKNGRVIENTRNSDIDTLMILASA
                     NDTKLINDGYIGKLIDNSSNSDITNNGNIDKKVNQVEDLEAKVDSIEKAIDSISQKVN
                     KIQDILDKLGFLKKFLS"
     gene            complement(2082..4493)
                     /locus_tag="KR294_003399"
     CDS             complement(2082..4493)
                     /locus_tag="KR294_003399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding cysteine protease Cwp84"
                     /protein_id="HBH0241447.1"
                     /translation="MRKYKSKKLSKLLALLTVCFLIVSTIPVSAENHKTLDGVETAEY
                     SESYLQYLEDVKNGDTAKYNGVIPFPHEMEGTTLRNKGRSSLPSAYKSSVAYNPMNLG
                     LTTPAKNQGSLNTCWSFSGMSTLEAYLKLKGYGTYDLSEEHLRWWATGGKYGWNLDDM
                     SGSSNVTAIGYLTAWAGPKLEKDIPYNLKSEAQGATKPSNMDTAPTQFNVTDVVRLNK
                     DKETVKNAIMQYGSVTSGYAHYSTYFNKDETAYNCTNKRAPLNHAVAIVGWDDNYSKD
                     NFASDVKPESNGAWLVKSSWGEFNSMKGFFWISYEDKTLLTDTDNYAMKSVSKPDSDK
                     KMYQLEYAGLSKIMSNKVTAANVFDFSRDSEKLDSVMFETDSVGAKYEVYYAPVVNGV
                     PQNNSMTKLASGTVSYSGYINVPTNSYSLPKGKGAIVVVIDNTANPNREKSTLAYETN
                     IDAYYLYEAKANLGESYILQNNKFEDINTYSEFSPCNFVIKAITKTSSGQATSGESLT
                     GADRYETAVKVSQKGWTSSQNAVLVNGDAIVDALTATPFTAAIDSPILLTGKDNLDSK
                     TKAELQRLGTKKVYLIGGENSLSKNVQTQLSNMGISVERISGNDRYKTSISLAQKLNS
                     IKSVSQVAVANGVNGLADAISVGAAAADNNMPIILTNEKSELQGADEFLNSSKITKSY
                     IIGGTATLSSNLESKLSNPTRLAGSNRNETNAKIIDKFYPSSDLKYAFVVKDGSKSQG
                     DLIDGLAVGALGAKTDSPVVLVGNKLDESQKNVLKSKKIETPIRVGGNGNESAFNELN
                     TLLGK"
     gene            4721..5119
                     /locus_tag="KR294_003400"
     CDS             4721..5119
                     /locus_tag="KR294_003400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HBH0241448.1"
                     /translation="MIFKKHKETILYLFFGTLTTFVNIISYLFFTRVVSLNFIIANIL
                     AWILAVLFAYFTNKFFVFESKVIEIAFLFKEFLSFVSFRLFSGITEMLIMYIMIDLLF
                     INDIIVKVFTNIIVIVLNYVFSKMIIFKKL"
     gene            complement(5180..5887)
                     /locus_tag="KR294_003401"
     CDS             complement(5180..5887)
                     /locus_tag="KR294_003401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HBH0241449.1"
                     /translation="MVEATLFFSPHQDDEILSMGSAIIEHVEKSDTHVILCTDGSKSV
                     IRKVLDDGGACSYHIKDIHKYSLSEDEFSYNRDDEFKNSCKEMGVKESNIHIEENRAH
                     DGELNKEKAKEIILKYLEEYPNAKVKTVTPYKASGIHEDHRALGEAALELYKEGKIKD
                     LRFYVEPYDYNDFKKVNPNVKVWKLANSQENKLLNAMNAYKKWNPESGKYAIGYHSVK
                     SHFDELKSNKIQYVHAP"
     gene            complement(5958..6395)
                     /locus_tag="KR294_003402"
     CDS             complement(5958..6395)
                     /locus_tag="KR294_003402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small multi-drug export protein"
                     /protein_id="HBH0241450.1"
                     /translation="MEYVNLIFLSMIPIVELRGAIPMGLALNLNPVLVYISCIIGSTV
                     IGIPILLTFRYMLDYLKVKGYFKCFVDFVENKLHNRAKKLKSLSIVGIVLFVGVPLPT
                     TGTWSAACIASLLRMRLKDAILGIFLGNIVSGCVVFAISYHIF"
     gene            complement(6468..7829)
                     /locus_tag="KR294_003403"
     CDS             complement(6468..7829)
                     /locus_tag="KR294_003403"
                     /EC_number="2.7.8.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005950019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-phosphate glucose
                     phosphotransferase"
                     /protein_id="HBH0241451.1"
                     /translation="MQMIIDLIIILSSFILAYYTKFNLLAGVNSIGVYGYIITAICSV
                     VMYFILYNILDLYSAKRTSNLYKEIKEIINANIIGALILTLILFIIKLINYSRIVLML
                     FVMYNVILTSLSRVVLRSILRKYRSKGFNQKHCLVVGATETGKKLIGKIKKNKQWGYN
                     IIGCLDDDLYHLDRFEEILILGTIDEIETILEKTHVDIVFITIDSEKFYKFGEIIKQC
                     EKAGVKTNIVPYYYNYVPSKPYMDDLDGFPIIDTRHVPLDNYFNNACKRLFDIIFSII
                     GIIITLPIMLFSILMIKLTSSGKIIYKQTRVGLNRKNFDMYKFRSMKTQKEEEEITKW
                     TTKNDSRKTKWGSIMRKTSIDELPQFFNVIKGDMSIVGPRPERPYFVDKFKYEIPRYM
                     IKHQVRPGITGWAQVNGYRGDTSIEKRIEYDLYYIENWTFLFDVKIVFFTIFKGILNK
                     NAY"
BASE COUNT         2418 a         1334 c          865 g         3223 t
ORIGIN      
        1 agattatttt tctttattct agttttgtca atacttttat ttattttttt gttacattca
       61 attccaatcc ccatgttacc tccccaaagc ttattcaaat atatattgaa ctacatattt
      121 atctataagt ctgtttgtat ataaacctgt ttaactatat aactttagaa caattacaac
      181 acacacttca cttaaatata catattctta gctaagaaat ttctttagaa atccaagctt
      241 atctagtata tcttgtattt tattgacttt ctgacttata gaatctatag ctttttcaat
      301 tgaatcaacc ttagcctcta aatcctcaac ctgattaact tttttatcta tattaccatt
      361 attagttata tcactattag atgaattatc tataagtttt cctatatatc catcattaat
      421 caattttgta tcattagcag aagctaatat catcaacgta tctatatctg aatttctagt
      481 attttctata actctaccat ttttgtcacg aactgacaat atagtgattg tatcatggtt
      541 attaaatcca ccttctccga tatttctaac tataacattt accaaagtag catagttatt
      601 cacttcacca ttaggcatat ctactgtaat agtctttgaa caatctccct ttatattcac
      661 agttattggt ttatttgtta ccattctaaa agcttcattt acagtattct cttttggttt
      721 aaagtttata atatcattag gacttgctat atttatcata tcagttaatt cctcaacagt
      781 ttttgcttca aacacagttt tttcttgtag acttataatt tcatcaaaag cttcttcatt
      841 tccatttcca cctacctgtg ttatagtatt taatttttta gtactaagta tatctctttg
      901 ttttgtgttt aatttattac caaccaaaac aacaggagac tcattttttg cagccaatac
      961 tccaacagct aacgagtcta ttagctgatt ctcattttta ctaccatcct tagttacata
     1021 taaattactt aagtttgtat cagtgtaaaa cttttctata actttagcat tagtctcatt
     1081 tctatctttt ccactcactc tttctgcatt aggaaggctc ttttctacag ctcttgaaac
     1141 agaatttgta cctccaatta catatgcttt tataactttc tcatctctta taaatttatc
     1201 aaatgcttct actccatcct taggactaga caaaattata ggcatcttat tttgagctgc
     1261 tggtgctcca acactaacag catcactcaa tcctttttca ccatttacta cagcaacttc
     1321 cttaatatct tttatatcct taagcttatt agccaaaatc agtgaagttt catatctatc
     1381 cttaccatta attctttcta cattaagtcc attacctttt aacttgttct ctatatcttt
     1441 attaagtaca gcagtacctc ctatcaaata aatatcttta gctcctagac gttttatctc
     1501 tttttcagtc ctatcatcta gcttatcact ttctgtcaaa agtattggtg ctcctttagc
     1561 ctttgcaaat ggtgtagctg aaagtgcatc agctaatgaa ttgtcattaa ctaacactac
     1621 attagaacta gaactgtatg ccttttgact tatctttaca gcagtttcat atctaccatt
     1681 acctattaat ttttcctctg taagtgcata tgatggtatt atagaaatgc tacttaaagt
     1741 aagcgctatt gtcagtattg ttaaaatagt ttttggtgct ttcattatta ttccccctta
     1801 ttttgtttaa aatcttacta tatttatatt ataaaataac tttacactat tttacagttt
     1861 aaaattatta catttttcat caataataag aaaactatct aaaaatatag acaaacttat
     1921 ttttcattat ttaaatgata aaaatataaa ataacaaaaa agagtgcctc atgaactaaa
     1981 aacttcattt tgagacaccc ctttttgtta ttttatattt ataaacttct attgaatatt
     2041 ttttaataat aaaatgtata tccttactat cttttcattc actattttcc taaaagagta
     2101 tttagttcat taaaagcact ttcatttcca tttccaccaa ctctaatagg agtttctatt
     2161 ttcttagact taagtacatt tttttgactt tcatctaact tatttccaac tagaactact
     2221 ggcgaatcag ttttagcacc taatgctcct actgctaatc catctatcaa gtctccttga
     2281 ctctttgaac catctttaac aacaaaagca tatttcaaat ctgaactagg gtagaattta
     2341 tctattatct tagcattagt ttcatttcta ttacttcctg caagtcttgt tggatttgaa
     2401 agcttacttt ctaaatttga tgataaagta gctgttccac caattatata agacttagtt
     2461 atttttgatg aatttaaaaa ctcatcagca ccttgcaact cactcttttc attagtaagt
     2521 attattggca tattgttatc agcagctgct gcaccaacac ttattgcatc tgcaagtcca
     2581 tttacaccat ttgccactgc aacttgtgag acagatttta tactatttaa cttttgagct
     2641 agagatatac tagtcttgta tctatcatta cctgaaattc tttctaccga tatacccata
     2701 ttgctaagtt gagtttgtac attcttactt aaagaatttt ctccacctat tagataaact
     2761 tttttagttc ctaatctttg taactccgcc ttagtttttg aatctaagtt atcttttcct
     2821 gttaaaagaa ttggagagtc gattgctgct gtaaatggtg tagctgttaa agcatccact
     2881 attgcgtctc catttactaa tactgcattt tgtgaagaag tccatccttt ttggctaact
     2941 ttaactgctg tttcatatct atctgctcca gttaaagatt ctcctgaagt agcttgtcca
     3001 gaagatgttt ttgttatagc ttttataaca aagttacaag gagaaaattc actatatgta
     3061 tttatatctt caaacttatt gttttgaagt atgtagcttt cacctaagtt tgctttagcc
     3121 tcatataaat aatatgcatc tatattagtt tcatatgcta aggttgattt ttctctatta
     3181 ggatttgctg tgttgtctat aactactact attgctcctt taccttttgg taaactgtaa
     3241 gaattagtag gtacatttat gtatccagaa tatgatactg ttccacttgc aagttttgtc
     3301 attgaattgt tttgaggaac tccatttact actggtgcat aatatacttc atattttgct
     3361 cctacagagt ctgtttcaaa cataacagaa tcaagttttt cagaatctct gctaaaatca
     3421 aatacatttg ctgctgttac tttatttgac attatcttac taagaccagc atattcaagt
     3481 tggtacattt ttttatcact atctggtttt gatactgatt tcattgcgta gttatctgta
     3541 tctgttagta gagtcttatc ttcataagaa atccagaaga atcctttcat agaattaaac
     3601 tctccccaac tgctttttac taaccatgct ccatttgatt ctggttttac atcagatgca
     3661 aagttatctt ttgaataatt atcatcccat cctactatcg ctacagcgtg atttaatgga
     3721 gctctcttat ttgtacagtt atatgctgtt tcatctttat taaaatatgt tgaataatgt
     3781 gcataacctg atgtcactga accatattgc attatagcat tttttacagt ttccttatct
     3841 ttattaagac gaacaacatc tgttacatta aattgagtag gtgcagtatc catatttgaa
     3901 ggtttagttg caccttgtgc ctcagattta agattatatg gtatatcttt ttctaactta
     3961 ggacctgccc atgctgtcag atatcctatg gctgttacat ttgaactacc tgacatatca
     4021 tctaagttcc atccatattt tccaccagtt gcccaccatc ttaaatgttc ttctgataag
     4081 tcatacgttc catatccttt taatttaaga tatgcttcta aagttgacat acctgaaaaa
     4141 gaccagcatg tattaagact tccttgattt tttgctggtg tagtaagacc aagattcatt
     4201 gggttgtatg ctacacttga tttatatgct gatggaagac tacttctacc cttatttcga
     4261 agtgttgtac cttccatttc atgtggaaaa ggtattactc cgttatattt tgctgtgtct
     4321 ccatttttga catcttctag gtattgaaga tagctttcag aatactctgc agtttctact
     4381 ccatctagag ttttatggtt ttctgctgag acaggtattg ttgacactat taaaaagcaa
     4441 actgtcaaca atgctagtag ctttgacaat ttttttgatt tgtactttct catgtttacc
     4501 cccttgtatg tatttaattt ttattatatc agatttctaa atctaggtca tattttattt
     4561 tgataaaata aaaattgtaa gtaaatatta attgtaaaat attataattt tattttttat
     4621 gatattttac aatatgtcta tttgttaact gatatgctat actaaagtgt attagtgttt
     4681 ttaaagatag ttatatttga ttagtttagg agggttatat ttgattttta aaaaacataa
     4741 agagaccata ttatatttat tttttggaac acttactact tttgtaaata taatttcata
     4801 tttatttttt actagagttg tatcacttaa ttttataatt gcgaatattt tagcatggat
     4861 tcttgctgtc ttatttgcct attttactaa taagtttttt gtatttgaaa gtaaggtaat
     4921 tgagatagct ttcttattta aagaattctt atcttttgtt agttttagat tattttctgg
     4981 tattactgaa atgttaatta tgtatataat gattgattta cttttcataa atgatattat
     5041 agtaaaagtc tttactaaca taattgttat agttttgaat tatgtattta gtaaaatgat
     5101 aatttttaag aaactataat aaaaaatagt ctgctgaagt agcagactat tttttattat
     5161 atatgaggcg aattgtaagt taaggagcat gtacatattg aatcttattt gactttaact
     5221 catcaaaatg tgattttaca gaatgatatc ctattgcata ttttccactt tctggattcc
     5281 attttttata agcattcata gcatttagta gtttattttc ttgactattt gctaacttcc
     5341 agacctttac atttggatta acttttttaa agtcattata atcatatggc tctacataaa
     5401 atcttaaatc ctttattttt ccttctttat ataactctaa tgctgcctca cctagtgctc
     5461 tatggtcttc atgtattcca cttgctttat atggagtgac tgtttttact tttgcatttg
     5521 gatattcctc aagatatttt aatattatct cttttgcttt ttctttgtta agttctccat
     5581 catgagctct attttcttct atatgtatat tactttcttt gacacccatt tctttacagc
     5641 tgtttttaaa ctcatcatcc ctattatacg aaaattcatc ttctgataaa gaatacttat
     5701 gtatatcttt tatatgatat gaacatgccc ctccatcatc caaaactttc cttatgactg
     5761 atttacttcc atccgtacat aatataacat gcgtatcact tttttcaaca tgttcgatta
     5821 ttgcacttcc catacttaaa atttcatcat cttgatgtgg tgaaaaaaat aaagttgcct
     5881 ctaccaatta cgttcctcct attctataaa taaaaataaa tgtttattta aaagctttac
     5941 tattctacta aatgtactta aaatatatga taagatatag caaaaactac acatcctgaa
     6001 actatatttc caagaaatat acctaaaatt gcatctttca atctcattct aagtaaagaa
     6061 gctatgcatg cagcactcca tgttccagtg gttggtaatg ggactccaac aaataaaaca
     6121 atacctacaa tacttagcga cttcaatttt tttgctctat tatgtagttt attttctaca
     6181 aaatctacaa aacatttaaa gtaccctttt acctttaaat aatccaacat atatctaaat
     6241 gttaataata ttggtatacc tattactgtt gaaccaatta tacaggagat ataaactaat
     6301 acaggattta agtttagtgc aagacccata ggaattgccc ctctaagctc tacaattggt
     6361 atcatggata aaaatattaa atttacatat tccaatatat ttctccttat tataagtaat
     6421 ttaattcttt aattgagatt tgttttagtt ataaaataaa atctatctca atatgcattt
     6481 ttatttaata tccctttaaa tatagtaaaa aaaactattt ttacatcaaa taaaaatgtc
     6541 cagttctcta tgtaatataa gtcatattct attctttttt ctattgatgt atctcctcta
     6601 tatccattta cttgagccca acctgttatt ccgggtctta cttgatgttt tatcatatat
     6661 ctaggtattt catacttaaa cttgtctaca aaatatggcc tttctggcct aggacctact
     6721 attgacatat ctcctttaat gacattaaaa aattgtggta actcatctat acttgttttt
     6781 ctcattatcg aaccccattt ggtctttcta gaatcatttt ttgttgtcca cttagtaatc
     6841 tcttcttctt ctttctgtgt tttcatagat ctaaatttat acatatcaaa attttttcta
     6901 tttaacccaa ctcttgtttg cttatatatt attttccctg aagaagtcaa ttttatcatt
     6961 aatattgaaa acaacataat tggcaatgtt ataataatgc caattattga aaaaattata
     7021 tcaaatagtc ttttacatgc attattaaaa taattatcta atggtacatg tctagtatct
     7081 attattggaa atccatctaa atcatccata taaggttttg atggtacata attataataa
     7141 tatggaacta tatttgtttt tacacctgct ttttcacatt gttttattat ttctccaaat
     7201 ttataaaatt tttctgaatc aatagttata aatactatat ccacatgtgt tttttccaat
     7261 atagtttcta tttcatctat agttcctaaa attaatattt cttcaaatct atctaaatga
     7321 taaagatcat catctaaaca tcctataata ttatatcccc actgtttatt tttctttatt
     7381 tttccaatta attttttacc agtctctgta gctcctacta ctaaacaatg tttttgattg
     7441 aaccctttac ttctatactt tctcaatata ctccttaaca ctaccctact taaactagtt
     7501 aatattacat tatacattac aaataacata agaacaattc ttgaataatt tattaatttt
     7561 attatgaata gaattaatgt caatattaat gcacctataa tattagcatt aattatttct
     7621 tttatttctt tatataaatt acttgttcgt tttgcactat ataagtctaa aatattatat
     7681 aatataaaat acattacaac agaacaaata gctgttataa tatatccata cacacctatt
     7741 gaatttactc ctgctagtag attaaacttt gtataataag caagtataaa agatgataat
     7801 ataataatta aatcgattat catttgtata ttgtttaata
//
LOCUS       DAEPKC010000135         7802 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.136, whole genome shotgun sequence.
ACCESSION   DAEPKC010000135 DAEPKC010000000
VERSION     DAEPKC010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7802)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7802)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7802
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.136"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            305..1606
                     /locus_tag="KR294_003404"
     CDS             305..1606
                     /locus_tag="KR294_003404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBH0241452.1"
                     /translation="MGKSKDVEIEKSILGTILLDNKLSYKLDELNENMFMNDICLEIF
                     KIMKELKKENIVIDVATVKSKIDRKSLAIKTSDVTNLITWGQNFGLDGHIKILKENLA
                     RRSINQNCQNLLHSLNLGENIDTCIYKFESNIKEILDKDTYENDDVNSIAGKVLDFLE
                     NKKDIGFKFGIKLLDTTIGGLFKGELTTIAAKSGVGKTALALQIMLNSFKQGKKTLFI
                     SREMTSEQVFMRNICRVTGVSTRNMKSKEIDENDWKLIVNAIGDLSENNLIYINDKID
                     TISAIRKRIRQVKPDLLIVDYVQLLTSQKSMDKREREVATFSRELKNMTLDFNIPVIQ
                     LSQLNDEMKDSRPYGDRPMRDSKAIYHDSNNVVYIHQLKGSDYEEAVRDIGESEEAVR
                     ASEYRGIKMVDLIVAKCRDGQTRHKHFCYFGDKLHFQELNY"
     gene            1682..1957
                     /locus_tag="KR294_003405"
     CDS             1682..1957
                     /locus_tag="KR294_003405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBH0241453.1"
                     /translation="MLELRKIIELLEEHKIEVSIPKELHKYSLLEYLELCQQSGGTYF
                     YIKTLEGALKEARNELMIKLFNGKNYMELARMFEMSVINVRHIVRKK"
     gene            3400..3630
                     /locus_tag="KR294_003406"
     CDS             3400..3630
                     /locus_tag="KR294_003406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBH0241454.1"
                     /translation="MSNKKKKYANILANECVACGSCIKACPRSAISVPCGISAKINRD
                     LCVGCGICEKICPASVIEIITILKEEEGKCHE"
     gene            3623..4204
                     /locus_tag="KR294_003407"
     CDS             3623..4204
                     /locus_tag="KR294_003407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBH0241455.1"
                     /translation="MNNKKHWYDYLWIFSSIYLILGFVNIIFAWIGLICFFVPLAISI
                     VKGNKAYCNKYCGRGQLFNLLGNKLKLSRNRDIPKFIRSKWFRYGFLTFFMVMFANML
                     FSTYLVFEGSRNFKEVVTLLWTIKMPWQWAYHGTLVSPWVVQFAFGFYSVMLTSTVLG
                     LITMILFKPRSWCVYCPMGTMTQMICKAKSKSI"
     gene            complement(4779..5456)
                     /locus_tag="KR294_003408"
     CDS             complement(4779..5456)
                     /locus_tag="KR294_003408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBH0241456.1"
                     /translation="MISQNEIDILTHSLPFWDKLTDLQKELLISSANTSHYKKGNPVH
                     CGDSDCIGILIIKSGTVRTYILSDEGREVTLFRLDDGDVCILSASCILKTITFDVYVD
                     AETDCDIIQISSSVFAKLSTENIHAELFSYKLATERFSDVMWAMQQILFMSFDKRLAS
                     FLIDEIAKNGSSTINMTHEQIAKYMGSAREVVSRMLKYFAREGIVSLSRGGIKVLDKD
                     KLRSLTL"
     gene            complement(5645..7009)
                     /locus_tag="KR294_003409"
     CDS             complement(5645..7009)
                     /locus_tag="KR294_003409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBH0241457.1"
                     /translation="MKESNKRIELLGSAPISKALLSMGLPTMIGMMITALYNLVDAYF
                     VGGLGTSQMGAISVAFPLGQLVVGLGLLFGNGAASYIARLLGHGDNEKAGKVVSTSIY
                     SSIIVGTLVIIVIMIFLNPILKLLGATKSIMPYAISYASIYVVSSIFNIFNVTMTNIV
                     TSEGAAKTTMCAMLLGALLNMILDPIFIYTFGLGVRGASIATAISQIASTLVYVGYIL
                     SKKSIFSFRINECCFSKEIFSEILKIGIPTLIFQLLTSLAITLTNMEATKYGDSVIAG
                     MGAVTRITSLGSLVVFGFIKGFQPIAGYNFGSKNYDRLHIAIKTSILWTTIFCVVLGL
                     ILILFPKSIISQFTSGDILLIENGSKALRANGFSFMLFGFYTVYSTLFLALGKAKEGG
                     FLGMCRQGVCFIPIILIIPVFYGLNGILYAQPIADLMAAIIAGFMSIRLHKELNLLKI
                     NGMH"
     gene            7137..7658
                     /locus_tag="KR294_003410"
     CDS             7137..7658
                     /locus_tag="KR294_003410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBH0241458.1"
                     /translation="MATIDLIVLGIVKQQPKSAYDIQKAVEYRNISRWVKISTPSIYK
                     KVIQLEQKGYIESKTVKNGKMPEKAVYSLTELGETHFLDLMFDTSSKPINILLDFNAV
                     IVNLNSLTPEKQKLCLNNIEENVQELKKTIEENISIKTEVPDTAKAVLEQQLVLAQAL
                     ETWINSLKDNMGN"
BASE COUNT         3046 a          876 c         1349 g         2531 t
ORIGIN      
        1 gaacgatata ttaataattg gcagtaagtt atatcaaata agatattact atcaagtagt
       61 gaattatatt gaacaatata ttaataattg gtagtaaagt atatcaaata agatattgct
      121 attatgtagt aaattatata aaacaatgta tcagaataaa tagtatatta ataatttgta
      181 gtatatcatg acgaataata cagtcataac aaatagtgag tcataacaaa taatgtattt
      241 ataattgata atgtatttaa aaatcaaaat ataaaaactt ataaggaaag agagattaat
      301 ttatatgggt aaatcaaaag atgttgaaat agagaagtct attttaggca caattctttt
      361 agacaataaa ttaagctata agctagatga attaaatgaa aacatgttta tgaatgatat
      421 atgtcttgag atatttaaaa ttatgaaaga acttaaaaaa gaaaacatag tgattgatgt
      481 ggccactgtg aaatcaaaga tagatagaaa atctctagca ataaaaacga gtgatgtgac
      541 taatctaatt acttggggtc agaattttgg tcttgatggt catattaaaa ttttaaaaga
      601 aaatttagct agaagaagca taaatcaaaa ttgccaaaac cttttacaca gcctaaacct
      661 tggagaaaat atcgatactt gtatttacaa atttgaaagt aatataaagg agattttgga
      721 caaggatact tatgaaaatg atgatgtaaa tagtatagca gggaaggtgc ttgatttttt
      781 agaaaacaaa aaagatattg gatttaaatt tggtataaaa ttacttgata ccactatagg
      841 aggtcttttt aaaggagagc taaccacaat agcagctaaa tcgggggttg ggaagactgc
      901 tttggcactt caaataatgt taaattcatt taagcaaggt aaaaaaactt tatttataag
      961 tagagaaatg accagtgagc aagtatttat gagaaatata tgcagagtaa ctggtgtaag
     1021 tacaaggaat atgaaatcta aagaaataga tgaaaatgat tggaaactta ttgtaaatgc
     1081 tataggtgat ttaagcgaaa ataacttaat ttatattaat gataagatag atacaattag
     1141 tgcaattaga aagaggataa ggcaggtaaa gccagattta ttaatagtgg attatgtgca
     1201 actccttaca tctcagaaaa gcatggataa gagagaaagg gaggtagcta ctttttcgag
     1261 agaacttaaa aatatgactt tagattttaa tatacctgta atccaattaa gtcagttaaa
     1321 tgatgaaatg aaagattcaa gaccttatgg agatagacct atgagggata gcaaagccat
     1381 ctaccacgat agcaacaatg tggtttatat acatcaatta aaggggagtg attatgaaga
     1441 agcagtgaga gatattggag aaagtgagga ggcagttaga gcatcagaat acaggggaat
     1501 taagatggtt gatttaatag ttgcgaagtg tagagatgga cagactaggc ataagcattt
     1561 ttgttacttt ggggataagt tacattttca agaactaaat tattaggtca ataaagtagt
     1621 aataacaagc ttattaaaag tcgggaaata gcaaatagat tataaaatat gaggtgaaaa
     1681 tatgttggaa ttaagaaaaa ttatagaatt acttgaagaa cacaagatag aagtaagtat
     1741 tccaaaggag ttacataagt atagtttatt ggaatacctt gaattgtgtc aacaaagtgg
     1801 gggaacatat ttttatatta aaacactgga aggggcttta aaagaggcta gaaatgagct
     1861 tatgattaaa ttgtttaatg ggaaaaatta tatggaatta gcgaggatgt ttgaaatgag
     1921 tgttattaat gtcaggcata ttgttagaaa aaaatagata tttttggaga atacaagtgt
     1981 gatatacttc tgaaatagaa gttattatag ttgaaataaa attgtggtta ataaattaaa
     2041 gttgtgtata agtttaagat tatagaggag tataagtgtg attaacagca tgattttgtg
     2101 aataaaattg aggatatata tgagttaaat gtgtgattaa taaggtaagg ttgtgtataa
     2161 gattatgagt atttaaaagg aggggctata attaatagtg tagagttgtg tgtttgctta
     2221 agattatata ataatttaat agattaaact atactaataa ggtaaaatcg tgtgtttagt
     2281 taaagcttat tataaaatct tgatatgtga ttaatgatgc aatatgtgaa taaagttaag
     2341 attataatag atttaacctg tggctaatag aataaaattg tgaataaagt taagattata
     2401 ataggtttaa cctgtgatta atagagtaag agtgtaaata gagataaact tcaatatgag
     2461 cttaacctat gattaataga gtaagagtgt aaatagagat aaacttcaat atgagcttaa
     2521 cctatgatta atagagtaag agtgtaaata gagataaact tcaatatggg tttaacttgt
     2581 gattaataga gtagggtgta actaaagata aacttcaata tgagtttaac ttgtgattaa
     2641 tagagtaagg tgcaactaaa gataaacttc aatatgagct taacctatga ttaatagagt
     2701 aagaatgtaa atagagataa acttcaatat gggcttaact tgtggttaat agagtaagag
     2761 tgtaactaaa gataaacttc aatatgggtt taacttgtgg ttaatagagt aagaatgtaa
     2821 atagagataa acttcaatat gagcttaact tgtgattaat agagtaagag tgtaaataga
     2881 gataaacttc aatatgggat taacttgtga ttaatagagt aagagtgtaa ctaaagataa
     2941 acttcaatat gagcttaacc tatgattaat agagtaagaa tgtaaataga gataaacttc
     3001 aatatgggtt taacctgtgg ttaatagagt agggtgtaac taaagataaa cttcaatatg
     3061 agtttaactt gtggctaata gaataagatt gtgaataaag ttatagtttt agatgggtat
     3121 taacctgtta ctaatagaat atgattaggt gtaaaattat agagctgtat aagaaaatat
     3181 tatagatata ttaaatatta gataataaat atttatatag atacacaaaa gaaaaggcga
     3241 tatgaagcta aacttaatga cttcatatcg ttttttattt gaaactcctt tgtatttaga
     3301 gtgtgatttt taatattgag gttttatgtg attaagtcac agataaaaag taagtatctt
     3361 gatataattc ttatagatta ataatatagg gaggttatta tgtctaataa aaaaaagaag
     3421 tatgcaaata ttttagcaaa tgagtgcgtt gcttgtggta gctgtataaa agcatgtcca
     3481 agaagtgcta tctcagttcc atgtggcatt agtgcaaaaa ttaatagaga tttatgtgtt
     3541 ggatgtggga tttgtgaaaa gatatgtcca gcatctgtaa ttgagattat aacaatatta
     3601 aaagaggaag aaggtaagtg tcatgaataa taaaaaacat tggtatgact atttatggat
     3661 tttttcttca atatatttga tattgggatt tgtaaatatt attttcgctt ggattgggct
     3721 aatttgtttc tttgttccac tagctatttc tattgttaag ggaaataaag cttactgtaa
     3781 taagtattgt ggaagagggc aactgtttaa tttgcttgga aataaattga agctgtcaag
     3841 aaatagagat attcctaaat ttattagaag taagtggttt agatatgggt ttttgacatt
     3901 ttttatggta atgtttgcca atatgctttt ttcaacttat ttagtgtttg aaggaagtag
     3961 aaattttaaa gaagtagtga ctttgttgtg gactataaaa atgccttggc aatgggcgta
     4021 tcatggaact ttagtttcac cttgggtggt acagtttgca tttggttttt atagtgttat
     4081 gcttacatca actgttcttg gtttgattac tatgatattg tttaaacctc gttcatggtg
     4141 tgtttattgc cctatgggta ctatgactca gatgatatgt aaggcaaaga gtaagtctat
     4201 atagaaaggc tttatgtgat atttacagtt ttgttagaga tgagtagtag gtttgaatat
     4261 atatgacaaa tatatgagta taggggcata gatttagttt gtgtaaggta aactgattta
     4321 tgcttctttt ttatgtctta gattattggc taagtggaaa caatgaattt agatattaag
     4381 aattattcag ttatttgaag aaaatagaat aataattaac attatatgaa tggatattca
     4441 ttacatataa gccagttaat agcaagattt atttaatatg aaataggtca agtatttaaa
     4501 ctaaataagg tcatgacaat taatataagt atagatataa aaagattaga agttataact
     4561 tataaaaggt attctatata aatagtatgt ggaaaatagt caaattaact tattagaaac
     4621 aaaaaatata cataaaaaaa taaatgtaaa tatcaaataa gatactatat aaaaatagat
     4681 ataagtatct tttttattat tgaaattatg aaaatatatt tgatttcaca caaaaaagag
     4741 tgcctcatga actaaaaagt tcattttgag acacactttt acagtgtcaa agaacgaagt
     4801 ttatccttat ccaatacttt tataccacca cgagataaag acacaatacc ttctctagca
     4861 aaatatttca acattctcga tacaacttct ctggcactac ccatatactt agcaatttgc
     4921 tcatgagtca tatttatagt gctactgcca tttttagcta tctcatcaat taaaaaagat
     4981 gccaaacgct tatcaaaact cataaaaaga atttgttgca tagcccacat aacatcagaa
     5041 aaacgttcgg tagctaattt atatgaaaat aactctgcat gaatattttc tgtagataat
     5101 tttgcaaaaa cagaggaact aatctgtata atatcgcagt ccgtttcagc atctacatag
     5161 acatcaaaag ttattgtttt tagaatacag gaagctgata aaatacatac atctccatca
     5221 tcaagtcgga acagtgtaac ctctcgacct tcatctgaaa gtatgtatgt acgtactgtt
     5281 ccagacttta taatcaaaat accaatacag tcactatcac cacaatgtac tggattccct
     5341 tttttgtaat gcgaggtatt tgctgaagaa attaataatt ctttttgtaa gtcagtaagt
     5401 ttatcccaaa aaggcaagct atgtgtaagt atatcgattt cattttgtga aatcatacaa
     5461 tatctccttt cttaaattgt tataatccca tgatacaagt gaatagataa attgacaagt
     5521 agtttgttaa taggattatt tagtcagata gtaatagtat gatttatgta gaaaaaatat
     5581 gataatatat attcttgcta ttaatgagaa ggtaatatgt tttgatgata gtaggtttgt
     5641 ataactaatg cataccgttt atttttaaaa gattaagttc cttatgtaac cttatagaca
     5701 taaaaccagc aattatagca gccatcaaat cagctattgg ttgtgcatat aagataccat
     5761 ttaacccata gaatacagga ataatcaaaa ttatagggat aaaacagaca ccttgtctac
     5821 acatacctaa aaatccacct tcctttgctt ttcctagtgc gaggaataat gtagaataca
     5881 ctgtatagaa tccaaatagc ataaatgaaa acccatttgc cctaagagct ttactaccat
     5941 tttctattaa tagaatgtca ccacttgtaa attgtgaaat tatagatttt gggaagagta
     6001 tcaatataag accaagcact acacaaaata ttgtagtcca taatatggaa gtttttattg
     6061 ctatatgtaa tctatcgtag ttctttgaac caaaattata accagcaatt ggttggaaac
     6121 cttttataaa accaaataca acaagactac ctaaagacgt tattcgtgtt acagcaccca
     6181 ttccagctat cacagaatca ccatactttg tagcctccat attagttaat gtaatggcaa
     6241 gactagtcaa taattgaaat attaaggtag gtatgccaat ttttaggatt tctgaaaaaa
     6301 tttcttttga aaaacagcat tcgttaattc taaaactaaa tatacttttc ttgcttaaaa
     6361 tatatcctac ataaacaagt gttgaagcaa tctgtgagat agctgttgca atagaagcac
     6421 cccttacccc cagaccaaaa gtataaatga atattgggtc taaaatcata ttaagcaaag
     6481 cacctaataa catagcacac atagttgttt tagcagctcc ttcacttgtg acaatattag
     6541 tcatagtgac attgaatata ttaaaaatag atgacacgac ataaatgcta gcataagata
     6601 ttgcataagg cataatactt tttgtagctc ctaacaattt taaaattgga ttgagaaaaa
     6661 tcataatcac aataataact aatgtaccca ctataatact actgtaaata gatgtactta
     6721 ccacttttcc tgctttttca ttatcaccat ggcctaaaag tctggcaata tatgaagcag
     6781 ctccatttcc aaacaataat cctaatccca caacaagctg acctaatgga aatgcaacgg
     6841 atatagctcc catttgactt gttccaagtc cacccacaaa gtatgcatca accaaattgt
     6901 ataatgcagt tatcatcata cctatcatgg taggtaatcc catagataac aatgcttttg
     6961 agattggggc agaccctaat aattcaattc ttttgttact ttctttcata cttaacactc
     7021 ctcttctatt gacattaagt ctaaattata atactataaa ttatagtaag tatggaaaat
     7081 agtactataa tttatagtat ttgtcaatag taagaaaact aaaggagatg atttttatgg
     7141 ctacaataga tttaattgta ttgggaatag taaagcaaca acccaagagt gcttatgata
     7201 ttcaaaaggc agtggaatac aggaatatat cacgttgggt taaaataagt acaccatcaa
     7261 tttataaaaa agtaattcaa ttagaacaaa agggatatat tgaaagtaaa actgtgaaga
     7321 atggaaaaat gccagaaaaa gcagtttatt cattaactga attaggtgag acacattttt
     7381 tagatttaat gtttgataca tctagcaaac caataaatat tcttttagat tttaatgctg
     7441 ttatagtaaa tttaaatagc cttacaccag aaaaacagaa attatgtctc aataatattg
     7501 aagagaatgt tcaagagtta aagaaaacta ttgaggaaaa tataagtata aagacagaag
     7561 taccagacac agcaaaagca gtgttggagc aacagttggt gctagcacaa gcattggaaa
     7621 cctggataaa ttctttaaaa gataatatgg gaaattagaa ttagagaagc taacttaata
     7681 atcattaaac aaaaaccagc atatttaata atgagatatt agaaaaaata aaacaaatga
     7741 tataaactga aaagtatatt taaaataaag ctcacttaat tgagggagaa tgttaaactt
     7801 tt
//
LOCUS       DAEPKC010000136         7713 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.137, whole genome shotgun sequence.
ACCESSION   DAEPKC010000136 DAEPKC010000000
VERSION     DAEPKC010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7713)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7713)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7713
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.137"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            12..323
                     /locus_tag="KR294_003411"
     CDS             12..323
                     /locus_tag="KR294_003411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HBH0241459.1"
                     /translation="MYFTYIIRCKDDSLYTGYTSNIVRRMNEHKLGINSKYTRAKGFE
                     KLEVYFVTNTKSNAMKLEYYIKKLTRNKKLSIIKNPSILINLIDNKEDYIIGKEIEQL
                     T"
     regulatory      416..508
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            608..1402
                     /gene="thiD"
                     /locus_tag="KR294_003412"
     CDS             608..1402
                     /gene="thiD"
                     /locus_tag="KR294_003412"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HBH0241460.1"
                     /translation="MSNYKIPTLTIAGSDSSGGAGIQADLKTFSAIGTYGMSVITAIT
                     AQNTKGVFAVEDLNKKIIKKQIEAVFEDIPPRAVKIGMVSSPEIILEIVENLKKYNPK
                     YLVVDPVMISKSGYYLLKPEAKENLIKYLIPLAYIITPNIPEAEEITGIKIHNVDDMK
                     RVGEEILQLGPKFVLMKGGHLDGEAVDILVGKNIFKVYKSERIDKKNTHGTGCTLSSA
                     ITSYLALGYEITEAVNLSKIYITEAIKRSFDIGHGVGPVHHFYKFE"
     gene            1426..2214
                     /gene="thiM"
                     /locus_tag="KR294_003413"
     CDS             1426..2214
                     /gene="thiM"
                     /locus_tag="KR294_003413"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HBH0241461.1"
                     /translation="MYNLIKDVKKLNPLVIHYTNNVTINDCANVTLAVGASPLMSFSY
                     EEVEEMVSVANSVVINIGTMNSNMLDLFLLAGKAANKYNKPVVLDPVGVFASKARAEL
                     TSRLLNEVKFSVVKGNVSEIKFIGGFNVRGKGVDSFDEEEDSTEIIRKIAEKLECVVV
                     ATGKIDIITNGKGTYKINNGTDKLKGITGTGCMTASLIASFMAVTENILEAATMGVLT
                     MSLSGELANLNNPPIGTFKENLMNAIYQMDIDTLSKNSNIEFLN"
     gene            2237..2869
                     /gene="thiE"
                     /locus_tag="KR294_003414"
     CDS             2237..2869
                     /gene="thiE"
                     /locus_tag="KR294_003414"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HBH0241462.1"
                     /translation="MIDKESLKKCLKLYLVTDSEMLKGRDFYKCLEDAISSGITTVQL
                     REKNASGREFLRKAMKLREITKQYGVKFIINDRVDIALICDADGVHVGQSDIDVREVR
                     KLIGNNKILGVSARTLEEAICAKNDGADYLGVGSIFTTSTKLDAKSASFETVKEIKEK
                     VDMPFVLIGGINLDNIDKLKCLESDGYAIISAILKAEDISKEVEKWTLKI"
     gene            3008..3310
                     /locus_tag="KR294_003415"
     CDS             3008..3310
                     /locus_tag="KR294_003415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH0241463.1"
                     /translation="MIRILLVCVGGMSSTLLVNKMEKDAKKRNIDCKIWAVGEGDIKS
                     ELDNFDILLLGPQLRFMLDDVKSIVGDRAPVSIIDMVNYGTCNGHAVLNSVLEILK"
     gene            complement(3376..4125)
                     /locus_tag="KR294_003416"
     CDS             complement(3376..4125)
                     /locus_tag="KR294_003416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0241464.1"
                     /translation="MLNILWRSMKWRFKNPISFVVTILQPFLWLVLYSSIANQTMNNI
                     NINNYTAFILPGIIVLVVFSSCSSGGIINFIMKNSGSFYRVLIAPISRYSIVLGQLLE
                     AILVSFIEVTILCIVSIFFSVRIESGIGGILLMIVLIFMTAFFLSSLAYSISLLLPNE
                     IVYETIMTAIVLPIFFLSSALFPIESLSGGLKVAVMLNPFTHVINALRSLIFGETILI
                     GDILPVILLFLILCCSSFSLAMWRLKKEMVS"
     gene            complement(4119..5081)
                     /locus_tag="KR294_003417"
     CDS             complement(4119..5081)
                     /locus_tag="KR294_003417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0241465.1"
                     /translation="MLAIEIDNLVKEYKNGVKALNGLSFNVNAGEIFSLLGPNGAGKS
                     SLINILTTFYKPTSGNVTMFGKDLVDNPSWIRTQIACVAQQISIDEHLSLMENMVFQS
                     KMYKVEPQIAKQRIDSLIDKFDLSSYLKYPTSSYSGGVKRRLDIAMNMVSSPKILFLD
                     EPTVGMDVDSRKSMWDMLLKIRDEYGTTIFLTTHYLEEAEQLSDNICIMKNGKDLAQG
                     TPSSLRSYIRQNILRITFHNTEDIKKYKDSIKSTGLVKFMSVRENSIFISVNDSRTAF
                     TLINKWLLEHDIEFDAIEIVEPSLEDVFLALTSSKKSLKEEWEC"
     gene            complement(5085..5543)
                     /locus_tag="KR294_003418"
     CDS             complement(5085..5543)
                     /locus_tag="KR294_003418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HBH0241466.1"
                     /translation="MNCKIEIKNIESVTVATMRYNGPMTEATKYFPNVFKAIKGKSNG
                     APFFCYYDVDQKTGVAEMELCVPTAETPNRMGITTKEFPKTKALFFTHTGSYSNLPKT
                     YEMIFKYIHENNIKIQTPWREVFIKGPGMLIKGNPDNYITEIIFPLKEEE"
     gene            5899..6255
                     /locus_tag="KR294_003419"
     CDS             5899..6255
                     /locus_tag="KR294_003419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH0241467.1"
                     /translation="MNFELDNTTPIYLQIVKYIKRQIVTGELKPGETIPSRREMALNL
                     KVNLNTVQRAYKEMGDMNIINTFKNYQSSVTVDENILKNLKLELINESLSVFIEDMKA
                     INVSKEEVLKIIEDKY"
     gene            6327..7043
                     /locus_tag="KR294_003420"
     CDS             6327..7043
                     /locus_tag="KR294_003420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0241468.1"
                     /translation="MIEIKNVSKTYKRMQGLKIRKIEALKNVSFNIEKGKITALLGIN
                     GVGKSTMLKAIAGLINIDSGEIRIDGEKINEKVYNKLAFVPDVQSHFSNTTIKETFEF
                     MEIFYSKWNKEKSKEMMDIFKLDEDEIIDNLSKGNIARVKLILGFCQDPEYILLDEPF
                     TGIDLFKREEFIGVIAQYMEENQAIIITTHEIVEIESLVDEVVILDEGQIITSFNAEE
                     LREREGKSILDKMREVYKNE"
     gene            7036..>7713
                     /locus_tag="KR294_003421"
     CDS             7036..>7713
                     /locus_tag="KR294_003421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0241469.1"
                     /translation="MNKLLYLINVDLRRSNKFYIAYISFFSLITLSLNLFEINKFKNS
                     KFIMNLAIEDFGGIFYGLGILSNLGFIQSILFFGILGLFIYYVFMWKREFFSNNQSIY
                     TLMMLPQNKFKICISKSIALITMIYGFLISQTATLFICKYIFNFIFRNMPIINMNFAK
                     DLYYLNLKSIPIDFISFMAIYVFLLLIAISIVNCCILFIFSYINKFYVILITLLIIAG
                     LYFSTIYI"
BASE COUNT         2996 a          901 c         1259 g         2557 t
ORIGIN      
        1 tgtgatttaa ggtgtatttt acatatatta taagatgtaa agatgattct ctatacactg
       61 gatataccag taatatagtt agaagaatga atgaacataa attaggaatt aattcaaaat
      121 acacaagagc aaagggattt gaaaaactag aagtttattt tgtgaccaac acaaaaagca
      181 atgctatgaa gttagaatat tatataaaaa aattaactag aaataaaaaa ttgtctataa
      241 taaaaaaccc aagtatactt ataaatttaa ttgataataa agaagattat attattggta
      301 aggaaataga acaattaaca taaatattta tagtaacatt ataatgggtg catatggtgt
      361 aaaaacttga caataaatac tattgtaata taatgaagtt ataaatatag taaattaaaa
      421 tagctagggg agccaagagc tgagaggtat accgaccctt acacctgatc tggataatac
      481 cagcgtagga aagcttagta aaaattcaag tatgtattat ttgtgatata tgctatttct
      541 aagctatacc tattgtaggt atagcttttt taattaagtt atttaaatta aactttagga
      601 ggcaacaatg agtaattata aaataccaac acttacaata gccggctctg attcatctgg
      661 aggagctggg attcaggctg atttgaaaac gtttagtgca attggtactt atggtatgag
      721 tgtaataaca gctataacag cacagaatac taaaggagtt tttgctgtag aggatttaaa
      781 taagaaaata ataaaaaaac aaatagaggc agtctttgaa gatatacctc caagagctgt
      841 aaaaatagga atggtttcaa gtcctgagat tatacttgaa atagttgaga atctaaagaa
      901 atacaatcca aaatatttgg ttgtggaccc agtaatgata tctaaaagtg gatattatct
      961 attaaagcca gaggcaaaag aaaacttaat taagtatttg ataccacttg catacataat
     1021 tacaccaaat ataccagagg cagaagaaat aacaggaata aaaatacata atgtagatga
     1081 tatgaagaga gtaggagaag aaatactaca acttggacct aaatttgtac ttatgaaagg
     1141 gggtcattta gatggagaag cagtggatat tttagttggt aaaaatatat ttaaagttta
     1201 taaaagtgaa agaattgata aaaaaaatac acatggaaca gggtgcacat tatcttctgc
     1261 aataacatct tatctagcat taggatatga aataacagaa gcagtaaatc taagtaaaat
     1321 ctatataaca gaagcaataa aaagaagttt tgatataggt catggagtag gaccagtaca
     1381 tcatttttat aaatttgagt aataaaaaaa tattggaggt agaatatgta taatttaatt
     1441 aaagatgtaa aaaaattaaa tccattggta attcattata ctaataatgt aactataaat
     1501 gattgtgcta atgtaacttt agctgtagga gcaagtcctc ttatgagttt ttcatatgag
     1561 gaagtagaag aaatggtaag tgtagcaaac tctgtagtaa taaatatagg aactatgaac
     1621 tcaaatatgt tggatttatt cctattagct ggaaaagcag caaataagta caataaacct
     1681 gttgttttgg acccagttgg agtatttgca agcaaagcga gagcagaact tacaagtaga
     1741 cttttaaatg aagtcaaatt tagtgttgtt aaagggaatg tatcagaaat aaagtttata
     1801 ggtggcttta atgtaagggg taaaggtgta gattcatttg atgaagaaga agattctact
     1861 gagataataa gaaagattgc tgaaaagctt gaatgtgtag ttgtagcaac tggaaaaata
     1921 gatataataa ctaatggtaa aggtacatat aaaataaaca atggaactga taaattaaaa
     1981 ggaattacag gaactggatg tatgactgct agcttgattg caagttttat ggctgttact
     2041 gagaatatat tagaagcagc aacaatgggt gttcttacaa tgtctttaag tggggaatta
     2101 gctaatttaa ataatccacc aataggtaca tttaaagaaa atcttatgaa tgctatttat
     2161 caaatggata tagatacttt aagtaaaaat tctaatattg aatttttaaa ttaataaaga
     2221 gtaagggaga cttaaaatga ttgataaaga atctttaaaa aaatgtttaa agttgtattt
     2281 agtaactgac tctgaaatgc ttaaaggtag agacttttat aaatgtcttg aagatgcaat
     2341 atcttctgga ataacaactg tacaacttag agaaaaaaat gcttctggaa gagagttttt
     2401 aagaaaagct atgaaactta gagaaataac taaacaatat ggtgttaagt ttataataaa
     2461 tgatagagtg gatatagcac ttatttgtga tgcagatgga gtacatgtag gacagagtga
     2521 cattgatgtt agagaggtta gaaagcttat aggaaacaat aaaattctag gagtatcagc
     2581 aagaacttta gaagaagcta tttgtgcaaa aaatgatggc gcagactatt taggtgtagg
     2641 gtctatattc acaacatcta ctaaattaga tgcaaaatca gcttcgtttg aaactgttaa
     2701 agaaattaaa gaaaaagtag acatgccatt tgtactaatt ggaggtataa atttagacaa
     2761 tatagataaa cttaaatgtt tagaaagtga cgggtatgct ataatatcag ctatattaaa
     2821 agctgaagat atctctaaag aagtggaaaa gtggacatta aaaatataaa attggctctg
     2881 gtagtgaaaa aaatggaaaa atttgatata atctaagagt aaaatttaag caattataaa
     2941 tgataaactt ttctacatat actttttaat caagatatat gtagatttgg ttaaaaagga
     3001 gctataaatg attaggatat tgttagtgtg tgttggaggc atgtcttcta ccctattggt
     3061 aaataaaatg gagaaggatg caaaaaaaag aaatatagac tgtaaaatat gggcagttgg
     3121 agaaggagat ataaaatcgg agcttgataa ctttgatatt ttacttcttg gaccacaact
     3181 tagatttatg cttgatgacg taaagtctat agttggagat agagctccag tatctataat
     3241 agatatggta aactatggca cttgtaatgg tcatgctgtg ttaaattcgg ttttagaaat
     3301 attaaaataa ataataaaag tggattctat ataatagagt ccatttttat tatttgttat
     3361 taataggctt aaaacttagc ttaccatttc tttttttaat ctccacatag caagtgaaaa
     3421 acttgaacag cacaatatta aaaatagtag gataacaggc agtatatctc caataagaat
     3481 agtctcacca aatattaagc tacgtaaagc gttaataaca tgggtaaatg gattgagcat
     3541 cactgctact tttaatcctc cagataaact ttctataggg aaaagagctg aacttaaaaa
     3601 gaaaatagga agtacaattg cagtcataat tgtttcataa actatttcat ttggcaataa
     3661 taaacttata gaataagcta gacttgataa aaagaaggct gtcataaata tcagtactat
     3721 cataagtagg attccaccaa tgccagattc tatccttact gagaagaata tacttactat
     3781 acacaaaata gttacttcta tgaaagaaac taagatagct tctaataatt gaccaaggac
     3841 gattgaatac ctactgatag gtgcaattaa gactctatag aaacttccac tgttcttcat
     3901 tataaagttt ataataccac cactactaca agaagaaaac acaaccagta caatgatacc
     3961 tggtagtata aaagcagtat aattattgat atttatatta ttcatagttt ggtttgcaat
     4021 agaactataa agcacaagcc aaagaaaagg ttgtaatata gtaactacaa atgagattgg
     4081 atttttaaaa cgccacttca tactacgcca taagatattt aacattccca ttcctccttt
     4141 aagctttttt tagaacttgt aagtgctaaa aatacatctt cgagacttgg ctctacaatt
     4201 tctattgcat caaattctat atcatgttct aaaagccatt tatttattaa agtaaaagca
     4261 gttctactat cgtttacact tataaaaatt gaattttctc gtacgctcat aaactttact
     4321 aaaccagtac ttttaattga atctttatat ttttttatat cttcagtatt atgaaaagtt
     4381 atacgtagta tattttgtct aatgtaacta cgtaaacttg atggtgttcc ttgtgctaaa
     4441 tcctttccat tcttcataat acaaatatta tcactcaatt gttcagcttc ttcaagataa
     4501 tgagtagtta gaaatatagt tgtgccatac tcatctctaa tttttaataa catatcccac
     4561 atagattttc ttgaatcgac atccatacca acagttggtt catctaaaaa taggatttta
     4621 ggagatgata ccatattcat agctatgtcc aatctacgtt ttacaccccc tgaatatgat
     4681 gaagtaggat attttaagta actagataag tcaaacttat caattaaaga gtctattctt
     4741 tgttttgcaa tctgtggttc tactttatac attttacttt gaaataccat attttccata
     4801 agggataaat gttcatcaat agagatttgc tgtgctacac aagcaatttg agtacgtatc
     4861 caagaaggat tatctactaa atcttttcca aacattgtta catttccaga tgtaggtttg
     4921 taaaaggtag tcaaaatatt tataagagaa gatttaccag caccattagg accaagtaaa
     4981 gaaaaaattt ctccagcatt tacattaaag cttagaccat ttaaagcttt cacaccattt
     5041 ttatattctt ttactaaatt gtctatttca atcgctaaca tatattattc ctcctcttta
     5101 agtggaaata ttatctctgt aatatagtta tctgggtttc cttttatcaa catacctggt
     5161 cctttaataa atacttctct ccaaggagtt tgtattttta tattattttc atgaatatat
     5221 ttaaatatca tttcatacgt ttttggcaaa ttactataag agcctgtgtg agtaaaaaat
     5281 aaagcttttg ttttaggaaa ttcttttgta gttataccca tacgatttgg agtttcagca
     5341 gttggaacac ataattccat ttctgcaaca ccagtttttt ggtcaacatc atagtagcaa
     5401 aagaatggtg caccgttaga ctttcctttt atagctttaa atacatttgg aaaatacttt
     5461 gttgcctcag tcataggtcc attataacgc atggtagcca ctgtgactga ttcgatattt
     5521 ttgatttcaa ttttgcaatt catttgttta cctcctaatg tgtgttcata ttcttactag
     5581 atttttaagc attaatacat ataagatttt gattagttga aaacatataa tcttatctcg
     5641 tttgcttgtt ttcaagtcta acataacata aaatatatat cctctcattt gatgctccat
     5701 tttgtaaagt tattatttaa gctttacttt agatttttta gcaaattaaa ataaagcaat
     5761 ttataaaata agtatttaca aattaagtgt attaatcgta taatacactt aataggatac
     5821 tagataaagt ctgaaataaa ggcgtatttt tttaaagtaa gtgtactatc gtattaatac
     5881 actagaatag gaggaatcat gaattttgaa ttagataata caactcccat ttatttgcaa
     5941 atagtaaagt atataaagag acaaatagta acaggagagt tgaaaccagg agagacaata
     6001 ccatcaagaa gagaaatggc acttaatcta aaagtaaact taaatacagt tcaaagagca
     6061 tataaggaga tgggtgatat gaatataata aatactttta aaaattatca aagcagtgta
     6121 acagttgatg aaaatatatt aaaaaattta aaattagagc ttataaatga atcactatct
     6181 gtttttatag aagatatgaa agcaataaat gttagcaaag aagaagtttt aaaaataata
     6241 gaagataagt attagttttt taacaaatag aaaacttagt ttagaaagtt tatttataag
     6301 catattggat gtggaggata gtaaatatga tagaaataaa gaatgtcagc aaaacatata
     6361 aaaggatgca agggcttaaa ataagaaaga tagaagcttt aaaaaatgta agttttaata
     6421 tagaaaaggg aaaaataact gcattacttg gtataaatgg tgttggtaaa tcaactatgt
     6481 taaaagcaat agcaggactt ataaacattg atagtggaga aattcgtata gatggagaaa
     6541 aaataaatga aaaagtatac aataaattgg cttttgttcc agatgtacaa tctcacttta
     6601 gcaatacaac aataaaagaa acatttgaat ttatggaaat tttttattca aagtggaata
     6661 aagaaaaatc aaaagaaatg atggacatat ttaaattgga tgaagatgaa ataattgata
     6721 acttgtcaaa aggaaacatt gcaagagtaa aattaatact tggattttgc caagacccag
     6781 agtacatact tcttgatgaa ccatttacag gaattgattt gtttaagagg gaagagttta
     6841 taggagtaat agcgcaatat atggaggaaa atcaagccat tatcataact actcatgaga
     6901 tagtagagat agaaagttta gttgatgagg ttgtaattct tgatgaaggg cagattataa
     6961 cttcatttaa tgcagaagaa ttaagagaaa gagaaggtaa atctatatta gataagatga
     7021 gggaggtata taagaatgaa taaacttcta tatctaataa atgtagattt gagaagaagc
     7081 aataagtttt atatagctta tatatcattt ttttcattaa ttacacttag tttaaattta
     7141 ttcgaaatta ataaatttaa aaattctaaa tttattatga acttagcaat agaagatttt
     7201 ggaggtatat tttatggact agggatactt agtaatcttg gttttatcca aagtatattg
     7261 ttctttggga tattgggact ttttatatac tatgttttta tgtggaaaag agagttcttt
     7321 tcaaataatc aaagtattta tacacttatg atgttacctc aaaataagtt taagatttgt
     7381 atatctaaat caatagcctt gataacaatg atatatggtt ttttgataag tcagacagca
     7441 acattattta tatgtaaata tatatttaat ttcattttta gaaatatgcc tataatcaat
     7501 atgaactttg ccaaagattt atattattta aacttgaaga gtataccaat tgattttatc
     7561 tcttttatgg ctatttatgt atttttacta cttatagcta tttctattgt aaattgctgt
     7621 atattattta tcttttccta tataaataaa ttttatgtaa ttttaatcac tttgctgatt
     7681 atagcaggct tatatttttc aacaatatat ata
//
LOCUS       DAEPKC010000137         7504 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.139, whole genome shotgun sequence.
ACCESSION   DAEPKC010000137 DAEPKC010000000
VERSION     DAEPKC010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7504)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7504)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7504
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.139"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            472..981
                     /locus_tag="KR294_003422"
     CDS             472..981
                     /locus_tag="KR294_003422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009528606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HBH0241470.1"
                     /translation="MSKELAINEQIKDKEIRVLSPTGEQLGVMPTKEAQAMANSKNLD
                     LVQISPNANPPVCKIMDYGKFRYEQARKEKEAKKKQKTIVVKEVRLRPGIEQNDLNTK
                     ANNAIKFLKKGDKVKVELRFRGRELGHKDIGKEVMLKFLDIIKEFGEPTKAPAFEGNN
                     MVVIIDPKK"
     gene            1009..1203
                     /gene="rpmI"
                     /locus_tag="KR294_003423"
     CDS             1009..1203
                     /gene="rpmI"
                     /locus_tag="KR294_003423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011721840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HBH0241471.1"
                     /translation="MPKMKTHRGAAKRLKKTGTGKLKRAKAFKKHILTKKSAKTKMNL
                     RKSTLVSDGDAKRIAQLLPY"
     gene            1259..1615
                     /gene="rplT"
                     /locus_tag="KR294_003424"
     CDS             1259..1615
                     /gene="rplT"
                     /locus_tag="KR294_003424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HBH0241472.1"
                     /translation="MARVKKAMNARKKHKKILKLAKGFRGSRSKLYRPANTFVMKALK
                     NAYIGRKLKKRDFRKLWIQRINAAARMNGISYSRLMNGLKLSGVEVNRKMLSEMAIQD
                     PEGFAKLAEVAKAKLA"
     gene            1925..2470
                     /locus_tag="KR294_003425"
     CDS             1925..2470
                     /locus_tag="KR294_003425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241473.1"
                     /translation="MNEKLMDCFVNPIKCKLLLEVFSNNRTTAKQLGEKFQDISKATL
                     YRYLNKMLKDDIIKVVEENKIRGTVEKVYAMKLDIADDVNKIIDENSGEEYAQLFTQY
                     MMGFLREFYEYAERKEKDILKDGSGFSVCPVYASIDEIVEVSKKIASILEPLRNNSHE
                     EGRRMHSIGVIITPPKEDEGK"
     gene            2472..2563
                     /locus_tag="KR294_003426"
                     /pseudo
     CDS             2472..2563
                     /locus_tag="KR294_003426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002605025.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="exopolyphosphatase"
     gene            2910..4835
                     /locus_tag="KR294_003427"
     CDS             2910..4835
                     /locus_tag="KR294_003427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBH0241474.1"
                     /translation="MKIKFVIMPLVIFLMVLFVGCQSTKDTEVKAKDTEIKILGTGDL
                     HSILTDSMVSYVNEEREKNKNLLMVDAGDFYGTQSREMWEWSSGKKLINIKRNGRAEY
                     DDIIKSSKDEVPIVKDMAKLKYDAVVLGDNEFVSNDKQSLDKLVSDFKNNNMPLVSAN
                     IYEQSGENYVQPYVMKNIKTDEGNVKVGILGLTIKEVGETLGLEDFEKDKKARELGEQ
                     ADYKGKLYANDLVEDAKKWIKVMEKESPDIIVAVVHSGEEPKTDRNPGNRIKELATTV
                     DGIDAIVAGHTHEKIDEHKYKNKSGDEVIVTQPGWHGDRVSEINFKLNKENGKWDIKE
                     KSSKLKIIDKEVSIVATADLHSHFSDKLTVDLVNERSNPIEPVVVDAGDFLDPQTDEM
                     TQWYKEWKSIRDNNSDKTISRCPMVMDMNQGMYDAVVLGNHEFVSEKDEFWSDERLLD
                     AVIEDFEQVAISVLSANIYRQSGKNYVKPYIIKDVETSEGNVKVGILGLTIKEVGKGL
                     KNVNLQEQFQYKDKLYANDLVEDAKKWVKVMKKKKPDIIVAVVHSGEEPKNPKHPGNR
                     IKELATTVDGIDAIVASHTHEKIDEHEYKNKSGEKVIVTQPGEHGKYYSKITFKVNKE
                     KGSWTINDKFSKTIEVE"
     gene            5236..7140
                     /locus_tag="KR294_003428"
     CDS             5236..7140
                     /locus_tag="KR294_003428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBH0241475.1"
                     /translation="MKIKFIIVASIIFLIVLLVGCQSTKDTEINVLATSDLHSIIPDN
                     LISYVEEERKYDENLLMVDAGDFFDMQSGEMNKWFTGQKLVRFKDGIPEYKKIAEPRE
                     GEVPLAKKMAKLKYDAVTFGNHEFVSNDKQSLDKLVSDFKNNNIPLVSANVYEQSGEN
                     YVKPYVMKNINTDKGTVKVGILGLTIKEVGERSRFKSFEQDKKARELGEQPQYKGKLY
                     ANDLVEDANKWVKVMEKKEKPDIIVAIVHSGEEPKNPKNPGNRIKELATTVEGIDAIV
                     AGHTHEKIEQHTYKNNSGEEVIVTQPGAHGNSISKINFKLDKKNDKWFIKDKYSELKV
                     FGKEVNIITTSGLNPKFSDEMAVNLFNERDRDVQPIFIDTGDFLNTNTKEMTKWAKEW
                     QYNENKGIYKKINEWPIVYLGYDAVVLGSHEFTEDKETFEEKKSTLDYIIENFEEMKI
                     PVLSANIYDESGENYVKPYIIHNVETREGNIKVGVLGLTTTDKDEEDLSSSSLSKDSK
                     TSKIPEETGKLYTNNLVKDASEWVKVMQKESPDVIVAVVHSDNNSTLKNPSSEVKKLA
                     MSVDGIDAIVVGHTKNKVEEHIYKNKSGDEVIVTQSGEDCYSKISLELRKENGKWNII
                     NKYSKAIKMK"
BASE COUNT         3153 a          754 c         1373 g         2224 t
ORIGIN      
        1 tatagtagca tattagaata taatatagga tttgttatgt agtatagtag tatattagaa
       61 tacaatatag aatttgttgg gtagtatagt gttatattag aatacaatat aggatttgtt
      121 atgtagaata tatagagtca tgtagaatat aaatatataa aaggattttg ggtataaatt
      181 taaaaattaa tagcaaaatg agtagtatag acatataatt agtagtagga agtaattaaa
      241 tttttcctaa acaaaaaaaa tagttgcaaa taatttgatt aagtgatata gtagataagg
      301 taagaataaa acaaagaaga agtccgcttc tcaccttacg ccggaggtta gtaaggtaaa
      361 tataagttaa agcttaattt taatttaagt ttgtttaaat ttggtaactt atattgcgga
      421 tgattacgtc atccgctttt tattttataa aaattttgga ggtgtcctac aattagcaaa
      481 gaattagcaa tcaatgaaca aataaaagat aaggaaataa gagtcctttc accaacaggt
      541 gaacaacttg gagtaatgcc tactaaagaa gctcaagcaa tggctaatag caaaaactta
      601 gatttggttc aaatctcgcc gaatgcaaat ccaccagtat gtaagataat ggattatgga
      661 aagtttagat atgagcaagc gagaaaagag aaagaagcta agaaaaaaca aaaaactata
      721 gttgtaaaag aagtaagact tagaccaggt attgaacaaa atgatttaaa tacgaaagct
      781 aataatgcta taaagttcct taaaaaaggg gataaagtca aagttgaact tagatttaga
      841 ggaagagaat taggacataa agacataggt aaagaagtta tgcttaagtt tttagatata
      901 ataaaagagt ttggagaacc aacaaaagcc cctgcatttg agggtaataa tatggttgta
      961 attatagatc caaaaaaata gatgattaac tgagaggagg aatttgtcat gcctaaaatg
     1021 aaaactcata gaggtgcagc aaagagatta aagaaaacag gaactggaaa gttaaagaga
     1081 gctaaagctt ttaaaaaaca tatattaact aaaaaatctg caaaaactaa aatgaactta
     1141 agaaaatcaa ctttagtaag tgatggagat gctaagagaa tagcacaatt attaccatac
     1201 taagatacag attgtaaata ataactatag aagagggata taaaaggagg tcataacgat
     1261 ggcaagagtt aaaaaagcta tgaacgctcg taaaaagcat aagaaaatat taaaacttgc
     1321 aaaaggattc agaggatcta gaagcaaatt atatagacca gcaaatacat tcgtaatgaa
     1381 agcattaaaa aatgcttata taggaagaaa gttaaagaag agagacttca gaaaactttg
     1441 gatacaaaga ataaatgcag ctgctagaat gaatggaata tcttattcaa gattaatgaa
     1501 tggattaaaa ttatctggtg ttgaagttaa cagaaaaatg ttatctgaaa tggctataca
     1561 agatccagaa ggatttgcaa aattagcaga agttgctaaa gcaaaattag cttagtattg
     1621 aatcatgaga tgtaaagtct ttgagttata taaataattc aaggactttt ttattttttg
     1681 aaaaatactt attagtgtca tgtacaacca attttataat gataaataaa ataagcaata
     1741 caatagaatt ttatgagatt tattataaga attgttacaa ttatttatga tagctataaa
     1801 aagtcatagt aaaaatgata ttgatgtatg ttgatatatg tataaagttt ccaatcaatc
     1861 ttgaattaat attatcaaca tgataatatt atcttattaa taatataaat aagggggaga
     1921 taatatgaat gagaaactaa tggattgttt tgtaaaccca attaaatgca agttattgct
     1981 tgaagttttt tcaaataatc gaactacagc taaacaatta ggagaaaaat ttcaagatat
     2041 atcaaaggca acgctttatc gttaccttaa taaaatgttg aaagatgata ttataaaagt
     2101 ggttgaagaa aataaaataa ggggaactgt tgaaaaagta tatgctatga agttagatat
     2161 agctgatgat gtgaacaaaa ttatagatga gaactctgga gaagaatatg ctcaactgtt
     2221 tactcaatat atgatgggat ttttaagaga attttatgaa tacgctgaaa gaaaggaaaa
     2281 ggatatctta aaagatggtt caggattttc tgtctgtcca gtatatgcta gtattgatga
     2341 gatagttgaa gtgagtaaaa aaattgctag tatactagaa cctctaagaa ataactcaca
     2401 tgaagaaggt agaagaatgc attctatagg agtgataatt actccaccta aagaggatga
     2461 agggaaataa atctgattta catggggtag agccaattta tacagggaat cgttttatga
     2521 tttacatatg tatccagagc aaagtatctc tgcttggatt gtacttcatt gtaccatttc
     2581 atctatctaa tgacttggag tggtacaatg aagtttttta atttttcata ttaatgacta
     2641 aagaaatgaa ctttagacca catatgcaat taggttgcat tatacaatta gaccagatat
     2701 acagaataaa aatcagtatt tttatagcag ataaattgac tgttattctt cttaaaaatc
     2761 atctattagt tattgttagc atattgaaag aaattatagg aatttattga ataaatgaat
     2821 attgcccata atcatataaa ctgctatagt ttaaaataaa gcaggacgtt aaattttata
     2881 gtaatctaaa aatttaagag ggggatttta tgaaaataaa atttgttatt atgccattgg
     2941 tgatattttt aatggtatta tttgtggggt gtcaaagtac aaaagataca gaagttaaag
     3001 caaaagatac agaaattaaa atattaggta caggtgattt gcattcaatt ttgacagact
     3061 ctatggtttc atatgtaaat gaggaaaggg aaaagaataa aaatctgctt atggtagatg
     3121 cgggagattt ctatggtaca caaagtagag aaatgtggga atggtcttct ggaaaaaagt
     3181 taattaatat taaaagaaat ggtagagcag agtatgatga cataattaag agtagtaaag
     3241 atgaagtacc tatagttaaa gatatggcaa agttgaaata tgatgctgta gttttgggag
     3301 ataatgaatt tgtttcaaat gataagcaaa gtcttgataa actggtttct gattttaaaa
     3361 ataataatat gccattggta tcagcaaata tatatgaaca atctggagaa aattatgtac
     3421 aaccatatgt aatgaaaaat attaagacag atgagggcaa tgtaaaagtt ggaatactag
     3481 gtcttactat aaaagaagta ggggaaaccc ttggtcttga ggattttgaa aaggataaaa
     3541 aagctagaga gcttggagaa caagctgatt acaaaggaaa attatatgca aatgatttag
     3601 tagaagatgc aaagaaatgg ataaaagtta tggaaaaaga aagtccagac ataatagttg
     3661 cagttgtaca ctcaggggaa gaacctaaaa cagatagaaa tccaggaaat agaataaaag
     3721 agttagcaac tacagtggat ggaatagatg caattgtagc tggtcatact catgaaaaaa
     3781 tagatgaaca caaatataaa aataaatctg gagatgaagt aattgttaca caaccaggtt
     3841 ggcatggaga tagagtatca gagattaatt tcaaattaaa taaagagaat ggaaagtggg
     3901 acataaagga aaagtctagt aaattaaaaa taattgataa agaagtaagt atagttgcta
     3961 ctgcagattt acattcacat ttctctgata aattaacagt tgaccttgtt aatgaacgta
     4021 gtaacccaat tgaacctgtt gtagtagatg caggcgactt cttagaccct caaacagatg
     4081 aaatgactca atggtataaa gagtggaaaa gtataagaga taataatagt gataaaacga
     4141 ttagtagatg cccaatggtc atggatatga atcagggaat gtatgatgca gtagtacttg
     4201 gaaatcatga atttgtatcc gaaaaagatg aattttggtc agatgaacgc cttttagatg
     4261 ctgttataga ggattttgaa caggtggcaa tttctgtgtt atcggcaaat atatataggc
     4321 aatctggtaa aaattatgtt aaaccatata ttataaaaga tgtggagacg agtgaaggta
     4381 atgtaaaagt aggaatattg ggacttacta taaaagaagt aggtaaaggt cttaaaaatg
     4441 taaacttaca agagcaattt caatataagg ataaattgta tgcaaatgat ttagtggaag
     4501 atgcaaagaa atgggtaaaa gttatgaaaa agaaaaaacc agatataata gttgcagttg
     4561 tacattcagg agaagaacca aaaaatccaa aacatccagg aaatagaata aaagaactag
     4621 caactacagt agatggaata gatgcaattg ttgctagtca tactcatgaa aaaatagatg
     4681 agcatgaata taaaaataag tctggagaaa aagttatagt gacacaacca ggtgagcatg
     4741 gtaaatatta ttctaaaatt acctttaaag taaataaaga aaagggttcg tggactatta
     4801 atgataaatt cagtaaaaca attgaggttg aataacttta taaaatttat agataaagta
     4861 aattatctga tattgacatg atatataaga taaagtttct aatattagta taatgcataa
     4921 tgtgaaatat tttaataata agagaataaa caagacaaat aaaaatattt taacatgtaa
     4981 gatatagtat gaactattat actaatgctt actttataat ttgaacatat tagaataagt
     5041 cttatttgaa aattttagtg tattagagta agtattattt taccagtaaa aaatattgag
     5101 aactatatgt agatttgctt aaaaaggaat ttacatatag ttcttttcgt ataataaata
     5161 gtacaatctt atatggtaaa gataaagtgt gatattaaat tttattatca tccaaaatct
     5221 aaggaggagt ctcttatgaa aataaaattt attatagtag catcaataat atttttaata
     5281 gtattacttg tggggtgtca aagtactaaa gacacagaaa tcaatgtact cgccacaagt
     5341 gatttacatt caattattcc agataattta atttcctatg tagaagagga gagaaaatat
     5401 gatgagaatc tacttatggt agatgcagga gatttttttg acatgcaaag tggtgagatg
     5461 aataagtggt ttactggtca aaaattagta agatttaaag atgggatacc agagtacaaa
     5521 aaaatagctg aaccacgtga aggagaagtt ccattggcta aaaaaatggc aaagctgaag
     5581 tatgatgcag ttacatttgg gaatcatgaa tttgtatcta atgacaagca gagccttgat
     5641 aaattggttt ctgattttaa aaataacaat ataccattag tatcagcaaa cgtatatgaa
     5701 caatctggag aaaactatgt aaagccatat gtaatgaaaa atataaatac tgacaaggga
     5761 actgtaaagg ttggtatact tggtctgact ataaaagaag taggggaacg ttcaaggttt
     5821 aaaagttttg aacaagataa aaaggctaga gaacttgggg aacaacctca atacaaaggg
     5881 aaattatatg caaatgattt agtagaagat gcaaataagt gggtaaaggt tatggaaaaa
     5941 aaagaaaagc cagatataat agttgccatt gtacattcag gtgaagagcc aaaaaatcct
     6001 aaaaatccag gaaatagaat aaaagaacta gcaacaactg tagagggaat agatgctatt
     6061 gtagcaggtc atacacatga aaaaatagaa cagcatacat ataaaaataa ttctggtgaa
     6121 gaagtaatag taacacagcc tggagctcat ggtaatagta tatcaaagat taattttaag
     6181 ttggataaga agaatgataa gtggtttata aaagacaaat atagtgaatt aaaggttttt
     6241 ggaaaggaag taaatataat tacaacttct ggtctgaatc caaaattttc agatgaaatg
     6301 gcagttaatt tgtttaatga aagagataga gatgttcaac ctatatttat agatactgga
     6361 gattttttaa atactaatac aaaagaaatg actaagtggg ctaaagagtg gcaatacaat
     6421 gaaaataaag gcatctataa aaaaataaat gaatggccaa ttgtatatct tggttatgat
     6481 gctgtagtac ttggtagcca tgaatttaca gaggataaag agacttttga ggaaaaaaaa
     6541 tctacattgg attatattat agaaaacttt gaagaaatga agataccagt attatcagct
     6601 aatatatatg atgaatctgg agaaaattat gtaaaacctt atataattca taatgtagaa
     6661 actagggaag gaaatataaa ggttggagta ttaggtctta ctactactga taaggatgaa
     6721 gaagacttaa gtagctcaag cttaagcaaa gactcaaaga cttcgaaaat tcctgaagaa
     6781 acaggaaagt tatatactaa taatctagta aaagatgcaa gcgaatgggt aaaagttatg
     6841 caaaaggaaa gtcctgatgt gattgttgca gttgtacatt cagataataa tagtactcta
     6901 aaaaatccaa gtagtgaagt caaaaaactt gcaatgtcag tagatggaat agatgctatt
     6961 gttgtaggtc atacgaaaaa taaggtagaa gaacatattt acaaaaataa gtctggggat
     7021 gaggttatag taacacaatc tggagaagat tgttattcaa aaataagtct tgaactaaga
     7081 aaagaaaatg gcaagtggaa tatcataaac aaatatagta aagcaataaa aatgaagtga
     7141 atttattgat atataaacca ttattaacac tgatttttat aatataataa atactgattc
     7201 tataatataa ttaacactac tttttataat gtcatcaaca ctgattctat aatataatta
     7261 atactacttt tttaaatata atcaatactg attccataat ataattaaca ctactttttt
     7321 aaatataatc aatactgatt ctacaatatt attaatacta ctttttataa tataatcaac
     7381 actacttttt acaatataat caatactgat tctataatat aattaacact actttttaaa
     7441 tataatcaat atcgattcta taatattaac actacttttt aaatataatc aatatcgatt
     7501 ctat
//
LOCUS       DAEPKC010000138         7372 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.140, whole genome shotgun sequence.
ACCESSION   DAEPKC010000138 DAEPKC010000000
VERSION     DAEPKC010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7372)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7372)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7372
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.140"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(335..1681)
                     /locus_tag="KR294_003429"
     CDS             complement(335..1681)
                     /locus_tag="KR294_003429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBH0241476.1"
                     /translation="MKDLTTGHEGKSIFFFAMPMLIGSLFQQLYNTADSIIVGRFIGK
                     EAMAAVSGANPIMFLLVAALMGVSLGFSILVSQFYGSGDLKKVKATIDTTYILLFIGS
                     ILISILGIVFGGPMLKLMNTPESVFAQSKLYLTIIFSGILFSAGYNSVSAILRGLGDS
                     VTPLYFLIIATILNIVLDLTFIVVLRMGVEGVALATIMAQAVSFIISIIYLNKKHEVL
                     KFKIKGIVYDNKIFKDGLRLGLPSGVQQMLFSIGNMALQFLVNSYGTSAMAAFGAGLR
                     IENFISLPIMNLGSAVSTFVAQNIGAGENERVKKGIRESIKMTLVLAVTVIALILLFR
                     ENLIALFNTDKDVIKIGSSYLFIIGPFFLFIGTSFVLSSAMKGAGDSMFALISSIVSL
                     WLGRLPASYMLSKFFGTDGIWMGIPFGWTLGLIVTVIYYKKGHWKTKAIVNHRINE"
     regulatory      1931..2033
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            2127..3503
                     /locus_tag="KR294_003430"
     CDS             2127..3503
                     /locus_tag="KR294_003430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HBH0241477.1"
                     /translation="MQTTNSSTMQKLFPILTNKNVDMKKEIIAGVTTFLTMAYIIAVN
                     PNILSETGMPAGALVTGTCLAAAFGCILMGVVANLPFALASGMGLNAFFAYTVVLQMG
                     VPWEVALTAVFVEGIIFIVLSVSGVREAVVNAIPKNMKLAVTGGIGIFIALIGLVNSG
                     IVIGDQATLIKMGRFTPAVIITCVGLIIIAVLDKKRVKGSILFGIVVSSLLAWAFAFI
                     NPEYAQKLGIYLPGGLFKFESLAPIAGKIDLGYVLHPTNIGGFLVVVCTFLFVDFFDT
                     VGTLVGVCSKANMLDEKGNVPNVGRALLTDAVATTVGAGLGVSTVTTYVESSTGVIAG
                     GRTGWTAITVGILFLAAMFFSPVFIAIPSCATAPALIYVGYLMLGTVKDIEFDNITEG
                     VPAFVTIACMALTYSIGDGLTLGILTYVFVNIFYNIFGAKKAEDKKHVSVVMIVLAIL
                     FIIKLWLL"
     gene            complement(3617..4762)
                     /locus_tag="KR294_003431"
     CDS             complement(3617..4762)
                     /locus_tag="KR294_003431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBH0241478.1"
                     /translation="MNTFEQLKISSTLIDGLKKQDITSPTEVQSLVIGNIIQNKDLLI
                     NSQTGTGKTLAYLLPIFEKIDTSKRETQALILAPTHELVMQITNQVELLAKNAELSVT
                     SLALIGEVNIQKQIKNIKAVKPHIVIGSCGRVLDLIKQKKLKSHNIKTIVLDEVDNLL
                     NGKNITCIEDIIRTTLRDRQIIGCSASLTDSTIKICDKLMKEFEIIKTKEKSQINPNI
                     NHSYLLGEIRDKFTFLRKALAATNPKKAIVFVNNEKNIEVLVSKLNYHNYKAIGIFGN
                     MEKEDRKNAINKFKLGKAKILITTDLSARGLDIVDVSHVFNLDFPKSKNEYLHRCGRT
                     ARGNRSGNTISIITKKELDIIKDLQKEFNIVITPKTLQNGELIDIIK"
     gene            5015..5722
                     /locus_tag="KR294_003432"
     CDS             5015..5722
                     /locus_tag="KR294_003432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0241479.1"
                     /translation="MLKVINVSKSYKNKKVVSSVSFDVNDGELFGFIGHNGAGKTTTI
                     KAIVGIHDFEEGEVLINSKSIKKQPVECKKEMAYIPDNPDLYESLTGIQYLNFIADIF
                     EVAKDKREELIKYYSNKFELNKALGDLISSYSHGMKQKLAIISALIHSPKILILDEPF
                     VGLDPKASFILKEIMREFCDKGGCIFFSTHVLEVAEKICDKIAIIKDGNIIAYGTTEE
                     VKGSNSLESIFMELIEK"
     gene            5769..7364
                     /locus_tag="KR294_003433"
     CDS             5769..7364
                     /locus_tag="KR294_003433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0241480.1"
                     /translation="MSNLSILIKTNIINEFKLNALKKADGREKQKIMGMMLSVVIIAG
                     LLIFYVTSLSLSLVDILKQINQLEMLLIFGFGLSTLTTIVTSLYKTSSYLFQAKDLDL
                     LTSLPIKESTVLASKILMLVGANYLFSSICMLIPAVVYFLNSDVSITYFPYLILLFLA
                     LPLLPIVASSIIFLFIGQISSRIKYKNLVLIIGSIILMLLYTLLMSRLNSMSVEMLKN
                     SVSISETIRKVYPPIYYFVDALKTGSIVSFLAFIAISIIPFFMFVTLFAKKFKDINAK
                     MSEGYKSKNYEFKGQKTSRPSKALLKKEFKRYTSSFIYFLNSSAGLLFLIVGTILILL
                     FGADKVGELLKLNIDFNLIKIQLLGVFFFIIVMNCTTYCSISLEGKNLWILKSSPIDE
                     REIFWSKILMNFLLNAPLSILCLILVSIRLDFEIQFIIVSICLIVSFSMFVALMGLLS
                     NLLYPNLDWKNEVAVVKRSASMIVTMLVSLAYVIILGGIYVLLGISFLNIYIILASIL
                     TLILDFMIWRIISTKGVRIFKNL"
BASE COUNT         2590 a          948 c         1095 g         2739 t
ORIGIN      
        1 attattatgt aaaaattttc tgtaaataaa aactgtaaaa taacctttat tggtgcaatg
       61 ttaaatataa acgctagaat tacaaaaaac aatgcaacaa aagttttttc aactgagtct
      121 acagcccata tcaagatagt taaaaaagat aagcatatag aaaattttat gttgaaactg
      181 taattaagag agaagtagag aattatggta gctataacag tcatataaaa ttgttttggc
      241 ttaagaataa tacccatttt tatattcacc tccataattt attatatcat aatggaggtg
      301 aatacaatga atgtgaatac attttataaa aagattattc attgattcta tgatttacaa
      361 tagctttagt tttccaatgt cctttcttat agtagataac tgtaacaata agacctaaag
      421 tccaaccaaa aggaataccc atccaaattc cgtctgttcc aaaaaattta gaaagcatat
      481 aagaagctgg aagtcttcca agccataaag atactattga gcttataagt gcaaacatgg
      541 aatcaccagc acctttcatt gcacttgaaa gtacaaaaga agttccaata aataagaaga
      601 atggtcctat tataaataag taagaagagc caattttaat gacatcttta tcagtattga
      661 atagagcaat tagattttcc ctaaatagca aaattaaagc aataactgta actgctaaaa
      721 ctaaggtcat ttttatagat tctcgaatgc cttttttaac tctttcattt tctccagcac
      781 ctatgttttg agcaacaaaa gtagaaacag cagaaccaag attcataata ggtaagctta
      841 taaaattttc tatcctaaga ccagcaccaa aagctgccat agcagatgta ccataactat
      901 taactaaaaa ttgaagagcc atatttccaa ttgaaaacaa catttgttga actccacttg
      961 gaagtcctaa tctaagtcca tctttaaata ttttgttatc atatacaatt cccttgattt
     1021 taaatttaag cacttcatgt tttttattta aataaattat acttattata aatgatactg
     1081 cctgagccat tatagtggca agtgcaacgc cctcaacacc cattcttagc actacaataa
     1141 aagttaagtc taaaactata tttagaattg tggctattat cagaaaataa agtggagtta
     1201 ctgaatctcc aagtcctcta agtattgcac ttactgaatt atatccagca gaaaataata
     1261 ttccactaaa tattatagta agatacaatt ttgattgagc aaaaacggat tctggtgtat
     1321 tcataagctt aagcattggg ccaccaaata ctattccaag aatacttatt aatatagaac
     1381 caataaataa aagtatatat gtagtatcaa tagtagcttt tacctttttt aaatctcctg
     1441 agccataaaa ttgtgacact aaaatagaaa atccaaggct aacacccata agcgctgcca
     1501 ccaataaaaa cattataggg ttagctccag agactgccgc cattgcttct tttccaataa
     1561 atctaccaac tattatactg tcagctgtat tgtatagttg ttgaaataaa ctaccaataa
     1621 gcataggcat ggcaaaaaag aatatggact ttccctcatg acctgtagtt aaatctttca
     1681 ccttattcct ccaaataaaa aaattattaa tttattatag tataatctta acataaactt
     1741 tatatccaaa ctataaataa attgtatcaa aatatcatat atttttttaa aatgtaaaga
     1801 atataattat aatttgaatt taataaatca atatttaata taatcgaata ttaatacaaa
     1861 atcaatacaa tatatacgta tatattgaca aaattaatta tataaattaa aataatattc
     1921 gtaaagaaaa attcatgttt tgtactgtat aacatataat tttgacaata tgggtcataa
     1981 gtttctaccg gaataccgta aatattctga ctatgtatac tattatttag ttaattaaat
     2041 atttaattaa ctgaattatg aaggatacgg ctcagcttat caactactgt gtcgtttttt
     2101 tgtaaaattt aataggaggt gttgttatgc aaacaacaaa cagtagtact atgcagaaac
     2161 tttttccaat tttgactaat aaaaatgtcg acatgaagaa ggaaataatt gcaggagtaa
     2221 ctactttttt aactatggct tatataatag ctgtaaatcc aaatatttta tctgagacag
     2281 gcatgcctgc aggtgcactt gttacaggta cttgtttagc agcagcattt ggatgtattt
     2341 taatgggtgt agttgctaac cttccttttg ctttagcatc aggtatgggt cttaatgcat
     2401 tttttgcata tacagtagtt ttacaaatgg gtgttccttg ggaagtagct cttacagcag
     2461 tatttgtaga aggtattatt tttatagtat tatcagtaag tggagttcgt gaggctgttg
     2521 taaatgcgat accaaaaaat atgaaattag ctgttacagg tggtatagga atatttattg
     2581 cacttatagg tctagttaac agtggaattg ttattggaga ccaagccact cttatcaaaa
     2641 tgggtagatt tacaccagca gtaataataa cttgtgtagg attaataatt attgctgtat
     2701 tagataaaaa aagagttaaa ggttctatac tttttggaat agtagtgagt tcattacttg
     2761 cttgggcatt tgcttttata aatccagagt atgcacaaaa attaggtata tatttacctg
     2821 gtggattatt taaattcgaa agtttagcac caatagcagg taaaatagat ttaggatatg
     2881 tactacatcc aacaaatata ggtggttttt tagtagtagt ttgtacattt ttatttgttg
     2941 atttttttga tacagtaggt acattagttg gtgtttgttc taaagcaaac atgttagatg
     3001 aaaaagggaa tgttcctaat gtaggtagag ccttacttac agatgcggtt gcaactacag
     3061 ttggtgcagg acttggagta tctacagtta caacttatgt tgagagttca acaggagtta
     3121 tcgcaggtgg aagaactgga tggacagcaa taacagttgg aattttattc ttagctgcaa
     3181 tgtttttctc tcctgtattt atagcaattc catcatgtgc tacagcacca gctttaatat
     3241 atgttggata tttaatgctt ggtacagtta aggatataga gtttgataat ataactgaag
     3301 gtgttccagc ttttgttact attgcttgta tggcattaac atatagtata ggtgatggtt
     3361 taactttagg tatattaact tatgttttcg taaatatatt ttataatata tttggagcta
     3421 aaaaggcaga agacaaaaaa catgtttctg tagtaatgat tgttctggca atattattta
     3481 taataaaact ttggctacta taataggtat tatttaaaat tttaatttaa tataaaataa
     3541 agggctgtaa tttattatca attgtgatga taaactacag ctcttttgta tttgttgtat
     3601 ttttgtattt attgtattat ttaataatgt ctattagttc tccattttgt aaagttttag
     3661 gtgtaattac tatattgaac tctttttgca aatcttttat aatatctaat tctttttttg
     3721 ttattattga gattgtgtta ccacttcgat ttcctctagc agttcgacca catctatgca
     3781 ggtattcatt tttacttttt ggaaaatcca agttaaaaac atgacttaca tccacaatat
     3841 ctagtccacg agcagataaa tcagttgtaa ttaaaatctt tgctttacca agtttaaatt
     3901 tatttattgc attctttcta tcttcttttt ccatatttcc aaaaattcct attgctttgt
     3961 aattatgata atttagtttt gatactagga cttctatatt tttttcatta tttacaaata
     4021 caatagcttt ttttggattt gtagctgcta atgcctttct aagaaaagta aatttatccc
     4081 ttatctcacc taataaatat gagtgattga tgttaggatt tatttgtgat ttttcctttg
     4141 tttttattat ttcaaactcc ttcataagtt tatcacaaat ttttatagtg ctatcagtaa
     4201 gacttgcaga gcatcctata atttgtctat ctcttaacgt tgttcttatt atgtcttcta
     4261 tacaagttat attttttcca ttcaatagat tgtccacttc atctaagaca atagttttta
     4321 tattatgtga ttttagtttc ttttgtttta tcaagtctaa aactcttcca caagagccaa
     4381 ttactatgtg tggttttact gcttttatat tttttatttg tttttgtata ttgacctccc
     4441 caattaaagc taaagaagta acggagagtt ctgcattttt agccaataat tcaacctggt
     4501 ttgtaatctg cattactaat tcatgcgtag gtgcaagtat aagagcttgt gtttctcttt
     4561 ttgatgtatc aattttttca aatataggta aaaggtacgc tagtgttttt cctgttccag
     4621 tctgtgaatt aatcaataaa tccttatttt gaattatatt ccctataaca agtgactgaa
     4681 cttctgttgg agaagttatg tcttgttttt tgagtccatc tattagagtg gaacttattt
     4741 ttaattgttc aaatgtattc atattttact ccttatattt taataattat agtcaactat
     4801 tttttattat acattgttta ttcaaatcga actatatatt cttttataat tatgtgtaat
     4861 ttgaaagtaa atatcaatta tatttatacc tttatatttc tgataccttt gcattttata
     4921 gatttctaaa ataaacaaat aaaagttgta attgtttgat atttgttata tattgtatat
     4981 aacaaatatc aaaactataa tatggaggga aattatgtta aaagtaatca atgtatctaa
     5041 atcatataaa aataaaaaag tagtaagtag tgtctcattt gatgtaaatg atggagagct
     5101 ttttgggttt ataggacata atggagcagg taaaactact actattaaag caattgttgg
     5161 aatacacgat tttgaagagg gagaagtact aataaattct aaatctataa aaaaacagcc
     5221 tgttgaatgt aaaaaggaaa tggcatatat acctgataat ccagatttat acgagtcatt
     5281 aactggtata caatacctta attttatagc tgacatattt gaagttgcca aagataaaag
     5341 agaagagtta ataaaatatt attcaaataa gtttgaactc aataaagcat taggagattt
     5401 aatatcttca tattcgcatg gtatgaaaca aaaattagct ataatttcgg ctttgataca
     5461 cagtccaaaa atcttaattc ttgatgaacc ttttgtaggt cttgacccaa aagcttcctt
     5521 tatattgaag gaaattatga gggagttttg tgacaaaggt ggttgtatat ttttctcaac
     5581 acacgtttta gaagttgctg aaaaaatttg tgataagatt gccataataa aagatggaaa
     5641 tataattgct tatggaacta cagaagaagt taagggaagt aattcacttg aaagtatctt
     5701 tatggaatta atagagaaat aaaatgtttt ttatacaata tagtgtctaa agtgaggaat
     5761 gataaaatat gagcaatcta agtatattaa taaaaactaa tataataaat gaatttaaat
     5821 taaatgcgtt aaaaaaagct gatggtagag aaaaacaaaa aataatggga atgatgcttt
     5881 cagttgttat aatagcgggt ctattaattt tttatgtaac aagcttaagt ctctctttag
     5941 ttgatatctt aaagcaaata aatcaactgg aaatgctact gatatttggt tttggattat
     6001 caacattaac aactattgtt acatcattat ataaaacgtc atcatatcta tttcaagcaa
     6061 aagatttaga ccttttgact agtttaccta taaaagaatc tactgtacta gcaagtaaga
     6121 tattaatgtt ggttggagca aactatttat tttcttcaat atgtatgctt atacctgcag
     6181 tggtttactt tttaaattct gatgtaagta taacttattt cccttatttg atattgctat
     6241 ttttagcttt accattatta ccgatagttg cttcatcaat aatttttcta tttatagggc
     6301 agatatcatc aagaataaaa tacaaaaatt tagtattaat cataggtagc attatattga
     6361 tgttgcttta taccctactt atgtcaagac ttaattctat gtcagttgaa atgctaaaga
     6421 atagtgtgtc tatttcagag acgattagaa aagtatatcc tcctatatat tattttgttg
     6481 atgctcttaa aacaggaagt atagtttcat ttttagcatt tatagccatc tcaataatac
     6541 cattttttat gtttgtaact ctgtttgcaa aaaaatttaa agatataaat gctaagatga
     6601 gtgaaggata taagtcaaaa aattatgaat ttaagggtca aaaaacttca agaccttcaa
     6661 aagctttatt aaaaaaagaa tttaagagat atacttcttc gtttatatac tttttaaatt
     6721 catctgcagg tttgttattt ctaatagtag gtacaatttt aatattatta tttggagcag
     6781 ataaagtggg tgagttactg aaattgaata tagattttaa tcttataaaa atacaattat
     6841 tgggagtatt cttctttata atagtaatga attgtacaac atactgttca atttctcttg
     6901 aaggaaaaaa cttatggata ctgaaatctt ctccaataga tgaaagagaa atattctggt
     6961 caaaaatatt gatgaatttt ttattgaatg caccactatc tattttatgt ctaatattag
     7021 tatctataag attagacttt gaaattcagt ttattattgt atcaatctgt ttgattgtaa
     7081 gtttttcaat gtttgtagca ttgatgggat tattatcaaa tttattatac ccaaaccttg
     7141 attggaaaaa tgaggtggct gtagtaaaaa gaagtgcaag tatgatagtt acaatgttag
     7201 tatcattagc ttatgtaatt atacttggag gtatatatgt attacttgga atttcgtttt
     7261 taaatatata tattattttg gcaagtatac ttactttgat attagatttt atgatatgga
     7321 gaattatttc tactaaagga gtaagaatat ttaaaaattt ataggtgtat tt
//
LOCUS       DAEPKC010000139         7301 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.141, whole genome shotgun sequence.
ACCESSION   DAEPKC010000139 DAEPKC010000000
VERSION     DAEPKC010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7301)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7301)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7301
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.141"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            23..883
                     /locus_tag="KR294_003434"
     CDS             23..883
                     /locus_tag="KR294_003434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBH0241481.1"
                     /translation="MLLKKDRITFSEILILIVGCILMAISLNLFFNPHAIAAGGITGL
                     GVVLNSLFGVELWIVNLLLNVPLFIFAYKILSKKDCFKTVLGIIFLTIALKLTANMAT
                     LDITNDMYLAIISGSILMGVGQGLIFRINGSTGGTDLMALLLNKYFPTFSIPVLMGIV
                     DCVVVVLSGIVNRQVEIALYSTVALYILVKVSDLLIEGFNYSKSFTIISDLSKDISKK
                     IMEDLDRGATILKGEGAYTGENKNVLLVVVEKKEVVELKKLVKNVDPNAFIIITDIHE
                     ALGNGFKKIE"
     gene            1339..1905
                     /locus_tag="KR294_003435"
     CDS             1339..1905
                     /locus_tag="KR294_003435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HBH0241482.1"
                     /translation="MSVSLQKGQRVSLVKDNNPVKNLVVGLGWDMNKLGKKNYDLDAF
                     AIALTNQDKMNVRGDLVYFGNLKHPSKAIIHTGDNLTGKGEGDDEQIIVNLEDIPEYV
                     HKIVFGVSIYKAKKRDQDFGQMNNSFIRLIDSNSKQELFKYNLQEDFSGKVTVLAGEI
                     YRRNEEWKFNALGIGQNEELRELINTYK"
     gene            1945..2526
                     /locus_tag="KR294_003436"
     CDS             1945..2526
                     /locus_tag="KR294_003436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HBH0241483.1"
                     /translation="MGITLAKGQKVSLTKSNPGLKKVIVGLGWDINKYDGGFDFDLDA
                     SAFLTGTDGKVTNDGDFIFYNNLKHASGAVEYMGDNRTGVGDGDDEQINVDLSKIPQN
                     IAKISFSVTINEAITRRQNFGQVENSYIRIYNEETNEELIKYELGEDFSIETAIVVAE
                     LYRHNGEWKFNALGSGFEDGLAGLCKNFGVNIG"
     gene            complement(2583..3500)
                     /locus_tag="KR294_003437"
     CDS             complement(2583..3500)
                     /locus_tag="KR294_003437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBH0241484.1"
                     /translation="MTIRSLEIFVKVAECGKMSEVARNMYITQSSVSQAISEIEKEYG
                     VKLFDRISKKLYLTEAGKKLLGYGRHLLAVNEEMNDCMKHCAKNIRIRVGATVTVGTC
                     VISPIMLELYKVNPLIEPEVFVEDTRLIAKKLLNSELDIAIVEGKIKHPDIVTKSIIN
                     DNLVLICSHKHEFYKRDSIKVSELSNQPLIMRELGSGTRAQLEKQLKELKIPMNIRWS
                     CYNSEAILRAVVDNFGIAVISELLIEDYLKKHLLWACDIEGINLHRTFDIAYHRSKFF
                     TENISAFFDISVEYGKKQARKKSRSVNSL"
     gene            3630..5261
                     /locus_tag="KR294_003438"
     CDS             3630..5261
                     /locus_tag="KR294_003438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBH0241485.1"
                     /translation="MKVLIIGGVAAGTKTAAKIKREMGDNCSVTILNKGDDISYAGCG
                     LPYYVGKIIEDKSSLIVNTPESFSKLTGAEVRCGVEVTSIDRNAKQVTLKTLSTGEKE
                     NLSYDKLVIATGADPIKPPIPGIDLPGVFFVRTPNDAIKLRDSIENGIKRAVVIGGGF
                     IGLEIAENLSAMGIRVSVVDMAEHVMPGFDTDFAEYVENHMADKGIMIFTGDQVVGIE
                     GENKVEKLRTKNRAIKTDLVVMSVGIRPNTGFLKDTGLEFAPNNTIIADEYMLTNDKD
                     IYVVGDCAFVKNSLTNKPTWSPMGSSANHEGRICAQNISGKSKTYNGVLGTTVVKLPE
                     LNAGKTGLSKEIAEKEGYNVCSVTIATDDKAHYYPGASNFIIRMVAEKNTRKLLGVQV
                     MGPGAVDKIVDIAATAITLGADLYSLESMDLAYAPPFSTAIHPFVVAVNVLQNKLNGE
                     LDSVLLDEIEDFDSWTKLDVSKAPSIPSLRYIPVGEINGEIEGLAKDEKILLICAKGK
                     NSYMAQNRLRRFGYTNTKVLEGGILFYPNLKVMEE"
     gene            5264..6211
                     /locus_tag="KR294_003439"
     CDS             5264..6211
                     /locus_tag="KR294_003439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013378669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(4Fe-4S)-binding protein"
                     /protein_id="HBH0241486.1"
                     /translation="MSNVTAEQKKEVKGRGFLPSRDGEHFAARIITVNGVINASQAKK
                     IAEAAEKFGNGQLAFTTRLTVELPGVKFEDIEALSEFIASENLITGGTGSRVRPVVAC
                     KGTVCVHGLADTQALAAEIHEEFYKNWYDVKLPHKFKIGVGGCPNNCIKPDLNDLGIV
                     GQRVPDYDSELCVGCKKCAVVEVCPVKAAKLTDKGKLEIDSNLCNNCGKCIESCNFDS
                     IEEKESGYKVYIGGKWGKSVRPGTQIDRLFSKEELMTLIEKAILLFREQGNTGERFGI
                     TIDRIGADKFIEMLLSDEVLERKEEILEALLHLTGGAVC"
     gene            complement(6496..6759)
                     /locus_tag="KR294_003440"
     CDS             complement(6496..6759)
                     /locus_tag="KR294_003440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1883 domain-containing protein"
                     /protein_id="HBH0241487.1"
                     /translation="MEYSYSKMNLKKGDIVEVNLEKQANVILLDHINYVKFKNQRNYD
                     YYGGFAKKNPCRMRVPNTGTWYLVVNQDGNSGIVNFSINTIQN"
     gene            complement(6858..7103)
                     /locus_tag="KR294_003441"
     CDS             complement(6858..7103)
                     /locus_tag="KR294_003441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241488.1"
                     /translation="MFIDEELEGYILTCKISEDFKNIPEYSDEEFYVTVYKDESSDSG
                     YYALLENKEERVVWDGEVVANNIFNNLWIVINKVKTG"
BASE COUNT         2637 a          958 c         1152 g         2554 t
ORIGIN      
        1 tataatctat atataaggag tgatgttatt gaaaaaagat agaataactt tttcagaaat
       61 tttaatatta attgtaggct gtatattaat ggccatttct cttaacttat tttttaatcc
      121 acatgcaatc gctgctggtg gtataacagg acttggagtt gttttaaatt cattattcgg
      181 tgtagaactt tggattgtca atttactttt aaatgttcca ttattcatat ttgcttacaa
      241 aatactttca aaaaaagatt gttttaaaac ggttttagga ataatttttc ttaccatagc
      301 acttaagctt actgcaaata tggctacatt agatataaca aatgatatgt atcttgcaat
      361 tatatctggt tctattttaa tgggagttgg tcaaggactt atttttagaa taaatggctc
      421 tacaggtgga actgatttaa tggcactcct actaaataaa tattttccta catttagtat
      481 acctgtttta atgggtattg tagactgcgt tgtagttgtt ttatcaggta tagtaaatag
      541 acaggttgaa attgcacttt attcaactgt ggctttatac attttagtaa aagttagtga
      601 cttgcttatt gaaggattta attattccaa atcattcact attatatctg acctttcaaa
      661 agatataagt aaaaaaataa tggaagattt agatagaggt gcaactattc taaaaggaga
      721 aggtgcatat actggagaaa ataaaaatgt acttttagta gtagttgaaa agaaagaagt
      781 tgtcgaattg aaaaaattag taaaaaatgt cgaccctaat gcttttatta taattacaga
      841 tatacatgaa gctttaggta atggatttaa aaaaatagaa taactaacaa ataaatagca
      901 agtataatta acatatacaa attcaacttt ttatatgtta tattatactt gctatttata
      961 tattatactt gctatttata tattataatt gttgttttta agataaaaat taaatgtatc
     1021 aattattgtt ttatacaagt atttccaaat ccgttctcat ttagatagta tgcttagaaa
     1081 ttttagaatt attgagtcta actttattac ttactttact ttataacaat caaatacaaa
     1141 tttaaatatt ataaaactac aaaataattt aaagcatata atgtcaatat gtttaaatta
     1201 taaaatattc atgtagttat ataataaata atttataaat atagccaact tagcctaaat
     1261 acgtatataa tatagctaat atggttctta tacttgatac catcaataaa actaaaaata
     1321 taaaaaggag aacttaaaat gagtgttagt ttacaaaaag gacaaagagt tagcttagta
     1381 aaagataata atcctgtaaa aaatctagta gtaggcttag gatgggatat gaataaattg
     1441 ggtaaaaaaa attatgacct agatgcattt gcaatagcat tgactaacca agataaaatg
     1501 aatgttagag gtgacttggt ttattttgga aatcttaaac acccttctaa agctattata
     1561 cacactggag ataacttaac tggaaaaggt gaaggtgatg atgaacaaat aattgttaat
     1621 ttagaagaca tacctgaata tgtacataaa atagtttttg gagtttctat atacaaagct
     1681 aaaaaaagag accaggattt tggtcaaatg aacaactctt ttataagatt aattgattca
     1741 aattccaagc aagaattatt taaatataat cttcaagaag acttttctgg taaagtaaca
     1801 gttttggcag gagaaattta tcgtagaaat gaagaatgga aatttaatgc tttaggaatt
     1861 ggtcaaaatg aagagcttcg tgaattaatt aatacatata agtaataatt acaataaaaa
     1921 atttataatg aggagttggt ttaaatgggt ataactttag caaaaggaca aaaagtaagt
     1981 ttaacaaaaa gtaaccctgg tctaaaaaaa gtaatagtag gactaggatg ggatattaat
     2041 aaatatgatg gtggctttga tttcgattta gatgcctctg catttttaac tggaactgat
     2101 ggaaaagtaa cgaatgatgg agactttata ttctataata atttaaaaca cgcttctgga
     2161 gctgttgaat atatgggtga taatagaaca ggtgttggtg atggtgatga tgaacaaata
     2221 aatgtagact tatctaaaat acctcaaaat attgctaaaa tatcatttag tgttactata
     2281 aacgaagcaa ttacaagaag acaaaatttc ggacaagttg aaaattcata tataagaata
     2341 tataatgaag aaactaatga ggaacttatt aaatatgaat tgggtgaaga ttttagcata
     2401 gaaacagcaa tagttgtggc agaactatat agacataatg gagaatggaa atttaatgct
     2461 ttaggttctg gatttgagga tggacttgca ggattgtgta aaaattttgg cgttaatata
     2521 ggctaatata tctaaataaa aataagagta tattgatata ctcttatttt tatttagata
     2581 tattataaac tgtttacact tctactcttc tttctcgctt gttttttccc atattctact
     2641 gaaatatcaa aaaatgctga aatattttct gtaaaaaact tgcttctatg atatgcaata
     2701 tcaaatgtcc tatgtaaatt aataccttca atatcacaag cccacaaaag atgctttttt
     2761 aaataatcct caataagtaa ttcggatata actgcaatgc caaaattatc tacaactgct
     2821 cttaatatag cttcagagtt ataacatgac catctaatat tcattgggat ttttaattct
     2881 tttaattgct tttctaattg tgctcttgta ccacttccta attcacgcat aattaatggt
     2941 tgatttgaaa gttctgaaac ttttatagag tctcttttat aaaactcatg cttgtgtgaa
     3001 catataagta caagattatc attaataatg ctttttgtaa caatatctgg gtgcttaatt
     3061 tttccttcta caatcgcaat atctaattca ctattaagta atttttttgc aatcagtctt
     3121 gtatcttcta caaatacttc aggttctata agaggattta ccttgtataa ttctaacatt
     3181 attggactta ttacacatgt accaacagtt actgttgccc caactcttat acggatattt
     3241 tttgcacaat gcttcataca atcattcatt tcttcattta cagctaaaag atgcctccca
     3301 tatccaagaa gttttttccc tgcctcagtt aaatataatt tttttgaaat tctatcaaat
     3361 agcttaacac catactcttt ttctatttct gaaatagctt ggctaactga tgactgggta
     3421 atatacatat ttcttgctac ttcactcatt ttaccacatt cagcaacctt aacaaagatt
     3481 tcaagactac gaattgtcat attatcacaa ccttagcaaa cattagtaaa tgcttatgat
     3541 tttattaata ttttagtatt ttacaaatat attgtcaaga agtataattt tattatagag
     3601 ttataaagta gattggagtg tgatatattg tgaaagtatt aattataggt ggagttgctg
     3661 ctggaacaaa aactgctgca aaaataaaac gtgaaatggg tgataattgc tctgttacaa
     3721 tactaaataa aggtgatgat atttcttatg caggttgtgg tcttccatat tacgttggta
     3781 agataattga agataaatca tctttaatcg taaatacacc tgaaagtttt tctaaactaa
     3841 caggagcaga agttcgttgt ggagttgaag ttacatctat tgatagaaat gcaaaacaag
     3901 taactttgaa aacgctttca acaggagaaa aagaaaatct aagctatgac aaacttgtaa
     3961 ttgctacagg ggcagaccca ataaaaccac caatacctgg aatagattta cctggagtat
     4021 tctttgtgcg tactccaaat gatgctataa aactaagaga ttctattgaa aacggtatta
     4081 agagagctgt tgttattggt ggaggtttca ttggtcttga aattgctgaa aatctttctg
     4141 caatgggtat acgtgtaagt gttgttgata tggctgaaca tgttatgcct ggatttgata
     4201 ctgattttgc tgaatacgtt gaaaatcata tggctgataa aggcataatg atttttacag
     4261 gtgaccaggt tgtaggtatc gaaggtgaaa ataaagttga aaaacttcgt actaaaaata
     4321 gagctattaa aacagattta gtggttatgt cagttggaat ccgtcctaac acaggttttc
     4381 taaaagacac aggtttagaa tttgccccta ataatacaat tattgcagat gaatatatgc
     4441 ttacaaatga caaagatata tacgtagttg gagactgtgc ttttgtaaaa aattctttaa
     4501 caaataaacc tacatggtca cctatggggt catctgcaaa tcatgagggt agaatttgcg
     4561 cacaaaatat atctggaaaa tctaaaactt acaatggtgt tcttggaaca acagtagtaa
     4621 aattacctga gctcaatgca ggaaaaacag gtctaagtaa agaaatagct gaaaaagaag
     4681 gttataatgt ttgctctgta accatagcta ctgatgataa agctcattat tatccaggtg
     4741 catctaattt tattataaga atggttgctg aaaaaaatac tagaaaatta ttaggtgttc
     4801 aagttatggg acctggagcg gttgataaaa tagtagatat cgctgctact gcaataactt
     4861 taggcgctga cctttattca ttagaaagta tggaccttgc atatgcacca cctttttcaa
     4921 cagctattca cccttttgta gtggcagtaa atgttttaca aaataaactt aatggagaac
     4981 ttgatagtgt tttacttgac gaaattgagg attttgacag ttggactaaa cttgatgttt
     5041 caaaagctcc ttctattcct agtttacgtt atattcctgt tggtgaaatt aatggagaaa
     5101 ttgaaggcct tgctaaggat gaaaaaattc ttcttatatg tgctaaaggt aaaaatagct
     5161 atatggcgca aaatcgctta agacgctttg gctatacaaa tacgaaagtt cttgaaggtg
     5221 gaatactatt ttatccaaat cttaaggtaa tggaggagta aatatgagta atgttacagc
     5281 agaacaaaaa aaggaagtaa aaggtagagg ttttctacca agcagggatg gagaacattt
     5341 tgcagcacgt ataataactg taaatggtgt aataaatgca tcacaagcaa aaaaaattgc
     5401 agaagctgct gaaaaattcg gaaacggtca gttagcattt actactagac taacagtaga
     5461 attacctggt gtaaaatttg aagatattga agctctaagt gaatttattg ctagcgaaaa
     5521 tctaataaca ggtggaactg gatcaagggt tcgtcctgtt gtggcttgta aaggtactgt
     5581 ttgtgttcat ggtctagctg atacacaggc acttgctgct gaaatacacg aagaatttta
     5641 caaaaattgg tatgatgtaa aactacctca taagttcaaa attggtgttg gtggatgccc
     5701 taataactgt attaaacctg acctaaacga tcttggaatt gttggtcaac gtgtacctga
     5761 ctatgattca gagctttgtg ttggttgtaa aaaatgtgct gttgtagagg tctgtcctgt
     5821 taaagcagct aaattaacag ataaaggtaa acttgaaata gatagtaatc tatgtaataa
     5881 ctgtggtaag tgtatagaaa gttgtaattt tgatagtatt gaagaaaaag aatctggtta
     5941 taaagtctat ataggaggga aatggggaaa atcagttcgt cctggaacac agattgatag
     6001 attattttca aaagaggaac ttatgacttt aattgaaaaa gcaattcttt tatttagaga
     6061 acagggtaac acaggtgaac gttttggaat aactatcgat agaatcggtg ctgataaatt
     6121 tatagaaatg cttttatcag atgaagtttt ggaaagaaaa gaagagatac tagaggctct
     6181 tttacacctt acaggtggag ctgtatgcta acaataaata ttttaattgt acagataacc
     6241 tatggaaaaa attttagtta agaataatta aaattctata tatgatatat gataaatgag
     6301 gctatctcaa aacacagata cgcctttttt tcattgttga aatgataaag tatatttgag
     6361 ttcatataaa aaagagtgtc tcgtgaatta taaaattcat tttgaggcac ccacattatt
     6421 ttataataat tgcttattaa ttttatttta actatataaa aagtacaaaa agtaagaata
     6481 tccaatattc taaaattaat tttgaattgt attgattgaa aagtttacta ttccactatt
     6541 tccatcttga tttactacta gataccatgt tccagtatta ggaactctca ttctacatgg
     6601 atttttcttt gcaaatccac catagtaatc ataatttctt tgatttttaa atttcacata
     6661 atttatatgg tctaacaata ttacattggc ttgtttctct aaatttacct ctacaatatc
     6721 cccttttttt aagttcatct tactataact atattccatt gaattactcc tccagtatcg
     6781 aataatcttt gttatttact catctcaaat atgtaaaaat tcatttaaaa tattacaaat
     6841 actatataat tagactatta tccagtttta accttattta ttacaatcca aaggttatta
     6901 aaaatattat tggcaacaac ttctccatcc catacaactc tttcttcttt attttctaat
     6961 aaagcatagt acccagagtc agaactttca tctttataga ctgtaacata aaactcttca
     7021 tcactatatt caggtatatt tttaaagtct tcagatattt tacatgttaa tatataacct
     7081 tctaattctt catctataaa caaagcaatt cctccaatct ctatattttt actaattata
     7141 ccatattatg tcataaactt tttattttat tacaaatttc tattttttct ttactttata
     7201 aataaattat ataaattttc actttttaac tttatattat actaattaat tcttttattt
     7261 tcctatatat ttctttataa tttataaatt tagccattaa t
//
LOCUS       DAEPKC010000140         7260 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.142, whole genome shotgun sequence.
ACCESSION   DAEPKC010000140 DAEPKC010000000
VERSION     DAEPKC010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7260)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7260)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7260
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.142"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            469..609
                     /locus_tag="KR294_003442"
     CDS             469..609
                     /locus_tag="KR294_003442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241489.1"
                     /translation="MEKSNTTVTKKEKIEDIGMKLEHLLSEDITFYELLLEILYKEKE
                     EN"
     gene            complement(606..977)
                     /locus_tag="KR294_003443"
     CDS             complement(606..977)
                     /locus_tag="KR294_003443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0241490.1"
                     /translation="MESLGDRIANLRKELDINQKELATKVGITEASLSRYENNLREPK
                     SEIIVRLAKALETSTDYLLGVNDNTKISKEDKLIIENLSVSEKTKKLLEKIYSLEKED
                     REAIEKMIDNAYLKRFLKEEN"
     gene            1526..1783
                     /locus_tag="KR294_003444"
     CDS             1526..1783
                     /locus_tag="KR294_003444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241491.1"
                     /translation="MIIIRSQDKTNLMQINQIKIDGSQVYAVFESKIDTVKIGDYENN
                     TRAIQVLDNIQNFIENGTKYDYITSNKVRYNVNKIFQMPAK"
     gene            complement(1893..2573)
                     /locus_tag="KR294_003445"
     CDS             complement(1893..2573)
                     /locus_tag="KR294_003445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBH0241492.1"
                     /translation="MIWTFYSFICVILPCLIYQIVVIKRKNLKVEKNVMIHLVWVYIF
                     LLYIYLALSKAGIGSIWDIGRYSGLFRIDEINLIPFDSVGILTYILNIIMFMPLGFLL
                     PLIWKNFRNIINVSLTGLGFSLAIELCQLFNLRATDIDDLMMNTLGAVLGYFIWVGVN
                     NLFNLIKKKDIFPSIYKNIIQDEIAITIDDDISEKITSLYKNEAIIYLILAVLGEFLL
                     FNWSIIPY"
     gene            2833..3132
                     /locus_tag="KR294_003446"
     CDS             2833..3132
                     /locus_tag="KR294_003446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241493.1"
                     /translation="MKWIKWYSITCICIFIVVAFYMFIFPNKIETIDTSSAYSFVEKK
                     VPNSAVYQGYKKNPVDGTTTIYYSYDNSTHIVRLSHPEDYSRKINWDKVSNIRFD"
     gene            3456..5111
                     /gene="ilvD"
                     /locus_tag="KR294_003447"
     CDS             3456..5111
                     /gene="ilvD"
                     /locus_tag="KR294_003447"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020457899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HBH0241494.1"
                     /translation="MRSDIKKGIEGAPKRALMYGMGLTKEEIERPLIGIVNAQNEVIP
                     GHLHLDEIAEAAKNGVRMSGGLPLEFPAIGVCDGIAMGHVGMNYSLASRELIADSIEA
                     MAMAHGFDALVLIPNCDKIVPGMLMAAARLNIPSIVVSGGPMLPGKKNGKVYDFNSAM
                     EGVGACKDGTVSEEELEALAMNSCPGCGSCSGLFTANSMNCLTEALGMGIPYNGTAAS
                     HSGERKRIAKYAGMYVMELLKNDIKPRDILTIDAFKNAIAVDMAMAGSTNTVLHLPAI
                     AYESGIELNLNFFDEISEKTPCLTKLSPSGKHHIEDLHMAGGIPAIMNELSKINGINL
                     DCKTVTGKTIGENIRNCEIENEEVIHTLKNPYSNQGGLAILKGNLALNGAVVKKSAVA
                     EEMLVHEGPARVFNSEEEAVNAIFGKKINKGDVIVIRYEGPKGGPGMKEMLSPTSAVA
                     GMGLDKHVALLTDGRFSGATRGASIGHISPEAMEGGLIGLVEEGDIISINIPDKKLEL
                     KVDEVEIENRKLKFKPLEPKIKHGYLSRYAKLVTSANTGAVLK"
     gene            5455..6087
                     /locus_tag="KR294_003448"
     CDS             5455..6087
                     /locus_tag="KR294_003448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH0241495.1"
                     /translation="MNREEKSKNSKEKIIQSAFSLFSSKGYDSTSTQDIINLSGLSRG
                     AMYHHFKTKEDILRSVTKELYSQMNNFLEHLVADDTLTANEKIIELVVHSANDYTRRK
                     MVHCSWLEKIPFALIEEVRNLNNVVAPNIAKIIKQGVENKEFSCEYPEELAEMLVFSI
                     DILLDPVLFKREYSEVCNRLDFLLFMLKKMDIPLIDEYGIQKFKDLFRQL"
     gene            6110..6922
                     /locus_tag="KR294_003449"
     CDS             6110..6922
                     /locus_tag="KR294_003449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBH0241496.1"
                     /translation="MFYNAKSCQMMIGSNTVNYIEFGSGKKTLIILPGLGDGLFPLHG
                     KIQAIAFAFRYKQFAKDYKVYVFSRKNQITEKYSTRDMAKDQADIMKKLGIMKAEVMG
                     VSQGGMIAQYLAIDYPELVEKLVLAVTSSKQNDTIQNVICSWIDMAKKQNYNDLMIDT
                     AKKSYSERYLKKYQLFIPFLGKVGKPKDFKRFIIQATSCIEHNAFSELNKITCPTLII
                     GGANDKIVGNNASFHLAEKIKKSEIFIYEGLGHATYEEAQDFNERVLEFLNK"
BASE COUNT         2896 a          792 c         1116 g         2456 t
ORIGIN      
        1 aaaatgatta tattataaat cagttttttt gagacatctg gcttagattc tgaaagatat
       61 ttaatcaaag aaataaaact attaaataag caagtaaaca gctaaaatag tatgattttt
      121 atagaaaatt taaatccatc ctaaagaatt aaaagaaagt caaataaata taaaaaaatt
      181 atatatttat aaaaaatttt ataataaaaa tcatcctgaa aaatatataa aaatagaaaa
      241 aacatacaag attctacaat aatagatttt tttgttatta ttacgagttt tttattgcaa
      301 ctgtagaata aaagtattat tatataatta agataattat ctagggaaat tttggataat
      361 caaaatatat tttataaaat caaaatacaa ttacataaac tttattaaaa atttgttggg
      421 aatttctgac taacattaag aacgtaagtt tgttggggga tggtatatgt ggaaaagtca
      481 aacactactg ttacaaaaaa agaaaaaatt gaagatatag gaatgaaatt agaacattta
      541 ttgagtgaag atattacttt ttatgaatta ttacttgaga ttttgtataa agaaaaagaa
      601 gagaattaat tctcttcttt aaggaatctt tttaaatagg cattatcaat cattttttct
      661 atagcttctc tatcttcttt ttcaagagaa tatatttttt ctaagagctt ttttgttttt
      721 tcacttactg ataagttctc tatgattaat ttatcttctt tgcttatttt tgtattatca
      781 tttacgccta ataaataatc tgttgatgtt tctaatgctt ttgctaatct aactattatt
      841 tcacttttag gttctcttaa attattttca taacgtgaca agctagcctc agttataccg
      901 actttagtag caagttcttt ttgatttata tctaattctt ttcgtagatt tgctattcta
      961 tctcctaaac tttccatatg tacatcactc cttaccgaaa ttataagtta ttttgataaa
     1021 aagtaaaata aaattaccaa aaatataaaa aaaaaaggtt aaaataataa aatatattga
     1081 aaattaccat ttgtatatgt ataatatgaa ttatacaaat ggtaatttga tgagaggtgg
     1141 tatgttgaaa taagaaactg aattaattaa taaatacata gaaagttttg aaaaccttta
     1201 attgaaatat aaacaatatg tacaaaattt tttgcaagta aaattaccaa atgtataaaa
     1261 taaatcagta gcatagataa ttttatgctt taatacatta gattatttaa tttagttata
     1321 atggtcaaaa atgcaatcta caaataaaac aaagtattat caaaaaagta ttctttaaga
     1381 aaatttttta ttagagatgt aattgatata aataatcgta ttaaaaaata aaatactaag
     1441 tttaaaaatt taaataatct ataaatcaat tataaaatat tatttcttag aaattaaaat
     1501 gaattaagta aatggaggaa ttgatatgat aataattaga agtcaagata aaactaattt
     1561 aatgcagata aaccaaatta aaatagatgg tagtcaagtt tatgcagtat ttgaaagtaa
     1621 aattgatact gtaaaaatag gagattatga aaataataca agagctatac aagtgttgga
     1681 caatatacaa aacttcattg aaaatggaac aaaatatgat tatataacat caaataaagt
     1741 cagatacaat gttaataaaa tatttcagat gccagctaaa tagtgagtgt gcattttaat
     1801 ttaataacta aagcccactt tcttttgtgg tatgaaagag ggctttacat atttgtaaat
     1861 atcgaagtac acttgtttta tcaataaatt atttaataag gtataatgga ccaattaaac
     1921 aataaaaatt ctcctaaaac agcaagtatt aaatatataa tagcttcatt tttgtaaaga
     1981 gaggtaattt tttcgcttat gtcatcatca attgtaatag caatttcatc ttgaataata
     2041 tttttatata tagatgggaa aatatctttt ttctttataa gattaaataa attatttaca
     2101 cctacccata taaaatatcc taaaacagca cctaatgtgt tcatcattaa atcatcaata
     2161 tctgtagctc ttaagttaaa caattgacaa agttcaattg ctaatgaaaa acctaatcca
     2221 gttaatgaaa cattgataat atttctaaaa tttttccaaa ttaaaggtag taaaaatcct
     2281 aaaggcataa acataattat atttaaaata tatgttaaga tgccaactga gtcaaaaggt
     2341 attagattta tttcatcaat tctaaaaagc ccactatacc ttcctatatc ccatatgcta
     2401 ccaattccag ctttactaag tgctagatag atatataata aaaaaatata tacccatact
     2461 aaatgtatca ttacattctt ttcaactttc aaattttttc gttttataac gactatttgg
     2521 tatattaagc atggtaatat aacgcaaata aatgaataaa atgtccatat cattttattt
     2581 tgtccccttt caaatttatg tttttagttt tataagtact atctttatat taaactgtaa
     2641 gttttaaaaa tcttttaata aaatcttaaa aatttattaa tttataaaaa tatattatta
     2701 agattaaaaa atatatataa tcaaagtttc tacaattata tagttaggga tataaaaatt
     2761 ttatcgtatg cataaatatt ataaatatat ggaaataata atagtatatt ttggtaaagt
     2821 aggaggaatt ttatgaaatg gattaaatgg tatagtatta catgcatatg tatttttata
     2881 gtagtagctt tttatatgtt tatatttcct aataaaatag aaactattga tacttcatct
     2941 gcatatagct ttgttgaaaa gaaagtacca aatagtgctg tgtatcaagg atacaaaaag
     3001 aatccagttg atggtactac tacaatttat tacagctatg ataattcaac tcatatagtt
     3061 agattatcac atccagaaga ctattcaagg aagattaatt gggataaagt ttcaaacatc
     3121 agatttgatt aatctttaat atttataaaa gtctatatat ctaaggcaaa tatattatta
     3181 atcttattca tagttgagca ctttctatta tagaagtgcc tcttctgatt tatatcataa
     3241 aatattactc aacaatttgt aaaatatatt agtttataaa atatattgaa aagataatat
     3301 tatataatac aattgtgtaa gatattgata aaaaatcgta ataaattttc attagtatat
     3361 gctaatattt ttttacaatt ttcgtaatta attaatagaa aaatatatta taataatatt
     3421 atgaaaattt aaaaaagtaa gaaagaggta atattatgag aagtgatata aaaaaaggaa
     3481 tagaaggagc tccaaagaga gcgttaatgt atggaatggg tcttactaaa gaagaaattg
     3541 aaagaccatt aataggtata gtaaatgcac aaaatgaggt gattcctggt catctgcatc
     3601 ttgatgaaat agcagaagct gcaaaaaatg gagtaagaat gagtggtggt ttgccattag
     3661 aatttcctgc tataggggta tgtgatggta tagctatggg gcatgttgga atgaattatt
     3721 ccctggcttc aagagaatta atagcagatt caatagaagc tatggctatg gcacatggtt
     3781 ttgatgcttt ggtacttata cctaattgtg acaagatagt gccaggtatg ttaatggctg
     3841 ctgcaagact taatatacca agtattgttg tgagtggagg gcctatgctt ccaggtaaaa
     3901 aaaatggaaa agtatatgat tttaactctg caatggaggg tgttggagca tgtaaagatg
     3961 gaacagtaag tgaagaagaa ttagaagcgt tagccatgaa ctcttgtcct ggatgtggtt
     4021 catgttctgg tcttttcaca gcaaatagca tgaattgttt aacagaagct ttaggcatgg
     4081 gtataccata taatggtact gctgcgtcac attctggaga aagaaaaagg atagcaaaat
     4141 atgcaggtat gtatgttatg gagttactta agaacgacat aaaacctaga gatattttaa
     4201 caatagatgc ttttaaaaat gctatagctg tggatatggc aatggctggt tctacaaata
     4261 cagtacttca cttacctgca atagcttatg aatcaggaat agagcttaac ttaaattttt
     4321 ttgatgaaat aagtgaaaaa actccttgtt taacaaaatt aagtccaagt ggaaaacatc
     4381 atattgaaga tttacatatg gcaggaggaa taccagctat aatgaacgaa ctttcaaaga
     4441 taaatggaat aaatttagat tgcaaaaccg taacaggcaa gactataggg gaaaatataa
     4501 gaaattgtga aatagaaaat gaagaagtaa tacatacatt aaagaatcca tatagtaacc
     4561 aaggtgggct tgcaatattg aaaggaaatc ttgctctaaa tggagctgtt gtaaaaaagt
     4621 cagcagttgc agaagaaatg ttagttcatg aaggaccagc aagagttttt aattcagaag
     4681 aagaagctgt aaatgctatt tttggtaaaa aaataaacaa aggtgatgtt atagttataa
     4741 gatatgaagg tccaaagggt ggtccaggaa tgaaagaaat gctatctcct acatcagcag
     4801 ttgcaggaat gggacttgat aagcatgtag cacttcttac tgatggtcgt ttttcaggag
     4861 caactagagg agcatctata ggccatattt ctccagaagc tatggaaggt ggtttaatcg
     4921 ggttagttga agaaggagat ataatttcta taaacatacc agacaaaaaa ttagagttaa
     4981 aagtagatga agttgaaata gaaaatagaa aattaaaatt taaaccttta gaaccgaaaa
     5041 taaagcatgg atacttaagt agatatgcta aactggtaac atcagcaaat acaggagcag
     5101 ttttaaaata gtagactata tttatgtaaa ttagaaaaag ttaagaaaat attaattgga
     5161 tatcttaggt gttatagcac taatgaggta tcctttttat tttgtatgaa aaacacagca
     5221 aaatcttgat tatctttgaa aacaatacat ctctattata aggaatacga gtacagcata
     5281 gagatgtatc ttttagacct tgttgaggta atacaacttt ttaaaagttt gatgtggaat
     5341 gcttttcgtt ccatctgaac tatgaagaaa ttgaaagtca gttaattctt gacataataa
     5401 atattaaaat gtataataaa aaacaaacag acagtctgtt tttaggaggg aaatatgaat
     5461 agagaagaaa aaagtaaaaa tagtaaagaa aaaattatcc aatcagcatt ttcactattt
     5521 tcgtctaaag gatatgattc aacatctaca caagatatta tcaatttatc tggtctatct
     5581 agaggtgcaa tgtatcatca ctttaaaact aaagaagata tactgagaag tgtcacaaaa
     5641 gaactttact cacaaatgaa taatttttta gagcatcttg ttgctgatga cacccttaca
     5701 gcaaatgaaa aaataataga attggttgtt catagtgcga atgattacac acgtagaaaa
     5761 atggtacatt gtagctggtt agaaaaaatc ccattcgctt taatagagga agttcgtaat
     5821 ctcaacaatg tagttgcacc caatattgct aagataatta aacaaggtgt tgaaaataaa
     5881 gaattttctt gtgaatatcc agaggaatta gctgaaatgc tcgtttttag tattgatatt
     5941 ttacttgacc ctgtattatt taaacgtgaa tacagtgaag tatgtaatag gttggatttt
     6001 ttattattca tgttaaaaaa aatggatatt cctctaattg atgagtatgg tattcaaaaa
     6061 tttaaagatt tatttagaca attataatag gaaaagcgag gaatagacta tgttttataa
     6121 tgcaaaaagt tgtcaaatga tgataggaag taatacagtg aattatattg aatttggtag
     6181 tggtaagaag acactaatta ttttaccagg attaggagat ggtttatttc ctttacatgg
     6241 aaaaatacag gcgattgctt ttgcttttag atataagcaa tttgcaaaag attataaggt
     6301 ttatgtattt agtagaaaaa atcaaattac agaaaaatat tccacaaggg atatggctaa
     6361 agaccaagca gatataatga aaaaacttgg aattatgaaa gcagaagtaa tgggtgtttc
     6421 tcaaggtgga atgatagctc aatatctggc aattgattat cctgagttag ttgagaaact
     6481 tgtgttggca gttacttctt caaagcaaaa tgatactatc caaaatgtta tttgtagttg
     6541 gattgatatg gcgaagaagc agaattacaa tgatttaatg attgacacag caaagaaatc
     6601 ctattctgaa agatatttaa aaaaatacca attatttatt ccttttttag gaaaagtagg
     6661 taaaccaaag gattttaaac gatttattat tcaagcgacc tcttgcatag aacataatgc
     6721 cttttccgaa ttaaataaaa taacatgtcc aaccttaatt ataggaggtg ctaatgataa
     6781 aattgttgga aataatgctt cttttcattt agcagaaaag attaaaaaaa gcgaaatatt
     6841 tatctatgag ggattgggac acgctacata tgaagaagca caggatttta atgaaagagt
     6901 tttagagttt ttaaataagt aaacaccttt gttaaaaata tacatatgaa gattggaaat
     6961 ttaatgttaa aaatagaaac atgaaaatat gcttaactgg tatttttact attcataacc
     7021 aatttttgat acattatcta ctataaatac aaatatagct tcaatgtgat tatatattag
     7081 tgtattggta aagcacttat acaaacagag gaattttgta aattcatatt atacccacat
     7141 ttgttaactt atgaaaatat aatcaaaatt tttatgagat ttttatataa aaaatataat
     7201 gtttgtatac aaaaatattg aagatatttt agtaagtttt gtatataagc aaacatgtat
//
LOCUS       DAEPKC010000141         7211 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.143, whole genome shotgun sequence.
ACCESSION   DAEPKC010000141 DAEPKC010000000
VERSION     DAEPKC010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7211)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7211)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7211
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.143"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            281..931
                     /locus_tag="KR294_003450"
     CDS             281..931
                     /locus_tag="KR294_003450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH0241497.1"
                     /translation="MKVKSNLDEILYHKIIESLIRGEYSVGQKILLNDLCEKFEVSRT
                     PVVQAVKMLNKDGVLTIMTNGKVYVPEYEYDMVKQVCETRTLIETYALEKMMQEEEEV
                     FQQKLDVIKRYSDKCEEYYRQEKSVELALADLELHKAIVEGANNEILNDVYVGIQGRF
                     IVVNYLIRPLKNRNYEGTVQDHFEILKFIEDRDTKKAVDKLRNHIQGTIKRFCEDE"
     gene            1258..3324
                     /locus_tag="KR294_003451"
     CDS             1258..3324
                     /locus_tag="KR294_003451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S9 family peptidase"
                     /protein_id="HBH0241498.1"
                     /translation="MKEVVESLKKITKERIENTMKKLFTSETFLEYQFISDCQISPDG
                     GYTAFIVKKADIKENGYTSQVYILNNKTGELKQITSINSVGAYAWEDENTILFPALRN
                     EKVKEAVKNGKQCMSYYALSLNGGEAEELFRLPIKGGKLNPIGKGLYAVIDSYDNDRP
                     IVEGLPEEEQQKKINAYNKRHYEHFKEIPYAVNGEGYISRKRKRLYVYDSNINELKAI
                     TAPMFNVVGMKISDGKILYIGQEFKDVKGLKNGVYVFDTNTNTNVCILEKDKYIIKGF
                     ELYQNQVILNLTDALSYGNGENGDFYTIDIDTKEMKLLSGHQHHCIGNTVTSDVKMGA
                     GQTTKVDGEYIYYTSTVDMDCIIERIHIPTGKQEKVTQTGSVDFIDVKDGNIVCVGCL
                     GNGLPEVYTVENGTLCKKTHLNDHILEEYKISVPEYIESKGSSKWEIQGYVYKPVDYE
                     VGKKYPAVLAIHGGPRLTYGPYFMHEIQVFTSAGYFVFFCNPRGSEGRGNAFADIRKQ
                     FGDIDYIDFMEFTDTVLEKYTDIDKTKLAVEGGSYGGFMTNWIIGHTNRFAVACAQRS
                     IANWSGMEGTTDIGYYFCKGQTGASHMENHELQWKQSPLAYADKCVTPTLFLHGEKDY
                     RCYMQEAFQMFSALKIHGCPTKLCLFEGENHELSRSGRPKQKLQRLVEMLDWFSVYIK
                     KDNIGQ"
     gene            3341..5296
                     /locus_tag="KR294_003452"
     CDS             3341..5296
                     /locus_tag="KR294_003452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S9 family peptidase"
                     /protein_id="HBH0241499.1"
                     /translation="MEKIKIENSDIFEYIFPHDISCSPDGKHIAYIISNINEEKDCYE
                     HDLYVMDIKTEKQIHMTQTKDVTSFSWISNTELLFTSKRNKPKSGTTDFYTISIEGGE
                     AKKAFSIPKACSVPVSLGNKLWLLTTKNPTDSKKSEPDRAVEGVDYWTFTDKPFIRDG
                     ENFSQRRRVTLELYQEGENITKAITPKFCEVAGVDVSSDKNRILYTGQIYEDCATPFS
                     GLWEYHIDSGETKELVPQGKYQISLAKYIGKDKVMLQASTLDRSITQNHDIFILDLST
                     NEINMIASPDGMYATLLDVDAVYGGGRSNKVIGDKFIGARICRTMTEFNEFDTKTGNI
                     RIITKVDAFTSFDIYDNTMYTVMLKDYELAEIYSIDMTTGTMKKMTAFSKPYLDTHKV
                     SLPEKLTFVAKNKEEVDGFVIPPIDAKEGEKYPAVLFIHGGPKWAYGYMFTHLKQCVT
                     SKGMYVIYCNPHGGDGYGEKFLEMVERWGYVDYEHLMEFVDTCIEKYPGIDADRLGVA
                     GGSYGGYMTNWIIGHTDRFKAAVSQRGISNLITASLIIDFGDRIMKQTCGDKTPWNHE
                     EVLWNHSPIKYVKNVKTPTLFLHSDRDYRCFMGDTFQMFTALKQLGVDTEMYLFHGDT
                     HGLSRNGRPSNRIARANAIVDWFERYL"
     gene            5312..6502
                     /locus_tag="KR294_003453"
     CDS             5312..6502
                     /locus_tag="KR294_003453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HBH0241500.1"
                     /translation="MSDMLLWFSVVLVLFAIGDLIASKTKAKVSAVFVTLLLFLILFV
                     TKAIPADIIEKAGMTAAASWSVPMIMFSMGTMLNVKQFIDEWRTVLTAWLGIVAVIVC
                     VSLCIPLFGKSTVLTSIPVINGALPATTIMTQAALEKGLTLAAATATVVFAIQKFIGT
                     PIASRAALQEANRLLVEYHEAKSKGIDLANVDTDKKEAENTGTKVKQAFCEKYDKYYS
                     TNVCIFFIALFSYLGYELSEIIHVNYSIVCLVVGVIVTRIGIVPKDILEKGKIKGFIN
                     MVVFAAVIPSLAKVSLTDLISLFVPIVGMFAASIIGIFLMMKVLPGWKIIGSKPLAFG
                     VGFCQMLGFPTTYLISNEVCNAVGETEEERAYLMSKIMPKLVVGGMACMISIVVAGLM
                     VPML"
BASE COUNT         2685 a          836 c         1365 g         2325 t
ORIGIN      
        1 taatctatag tataatagtt taatttgaag tacaatggtt taatctatag tataatagtt
       61 taatttgaag tacaacgatt taatctatag tacaataact tgatttgcaa tacaatgaat
      121 taatctatag tataagagca tgatttacag tacaataatt taaattgtag tacaaaagta
      181 ctatcaaata agaatttcta ctttaaaaat attactaaaa gtaattaaag tccagtaatt
      241 caatataata tggcaaaaga atagaaataa ggtgagagta gtgaaagtaa agtcaaattt
      301 agatgaaatt ttatatcata agattattga aagtcttatt cgtggtgaat actctgtagg
      361 tcaaaaaata ttactaaatg acctttgtga aaaatttgaa gtaagcagaa caccagttgt
      421 acaagcagta aaaatgctaa ataaagatgg agtgcttact attatgacaa atggtaaagt
      481 gtacgtacca gagtatgaat atgatatggt aaaacaagtt tgtgaaacga gaacactgat
      541 tgaaacatat gctttagaaa aaatgatgca agaagaggaa gaggtttttc aacaaaagct
      601 agatgtaata aaaagatact ctgataaatg cgaggagtac tatcgtcaag aaaaatctgt
      661 agaacttgca ctagcagatt tggaattaca taaagccatt gtagaagggg caaataatga
      721 gattttaaat gatgtatatg ttggtataca aggaagattt atagtagtga actatttaat
      781 tcgaccatta aaaaatcgta attatgaagg aacagtacaa gaccattttg aaatattaaa
      841 attcattgaa gacagagata caaaaaaagc agtagataaa ctaagaaatc atattcaagg
      901 aactattaaa agattctgtg aagatgaata ataagttttg aagttactat atatacttat
      961 ctattaagtt gctaaatgta gtctaagtat aatctaatta tagtttaaac ataatctaaa
     1021 tataatctaa taaatataat ctaaatatag tgtaaataag tctaagtatg aattaaatat
     1081 agattaagta tagattaagt atagattaag tatgaattaa gcatgaatta agcatggatt
     1141 aaatatactt taaattacaa atattacaag gaagccagaa ggcttcctaa aaaaataacc
     1201 tttataaaat tttttatttt aaatttaaaa ttttttattt taaatttaaa ataaaaaatg
     1261 aaagaggtgg tagagagttt gaaaaaaatt actaaagaaa ggatagaaaa tactatgaaa
     1321 aagctattta cgagtgaaac atttttggaa tatcaattta taagtgattg ccaaatatca
     1381 ccagatggag gatatacagc atttattgta aaaaaagctg atatcaaaga gaatggttac
     1441 acaagccaag tttatatatt aaacaataaa actggcgaat taaaacaaat aacgtctata
     1501 aactctgttg gagcatatgc ctgggaagat gaaaatacta tcttgttccc tgctttgcga
     1561 aatgaaaaag taaaagaagc tgtcaaaaac ggtaagcaat gcatgagtta ctatgcttta
     1621 tctttaaatg gtggagaagc agaagaactt tttagactcc ctatcaaagg tggtaaattg
     1681 aatcctatag gaaaaggttt gtatgcagtt attgattctt atgacaatga ccgacctatt
     1741 gtagagggat tgccagaaga agaacaacag aaaaaaataa atgcttataa caaaagacat
     1801 tatgaacatt tcaaagaaat tccttatgct gtcaatgggg agggatatat tagcagaaaa
     1861 agaaaacgcc tatatgtata cgacagtaat ataaatgagt tgaaggcaat tacagcacct
     1921 atgtttaatg ttgtaggtat gaaaataagt gatggaaaaa tcttatatat agggcaagag
     1981 tttaaagatg taaaaggttt gaaaaatggg gtctatgtat ttgatacaaa cacaaacaca
     2041 aatgtctgta tattagaaaa agataagtat attataaaag gttttgaatt atatcaaaat
     2101 caagtgatac taaacctaac tgatgcttta tcttatggaa atggagaaaa tggagatttt
     2161 tatactattg atattgatac gaaagaaatg aaacttcttt cagggcatca acatcattgt
     2221 attggaaata cagtaacatc tgatgttaaa atgggtgctg gtcagacaac aaaggtagat
     2281 ggagaatata tttattacac ttctacagta gatatggact gcattattga aagaatacat
     2341 attccaacag gaaaacagga aaaagtaaca cagacaggtt cagttgattt tatagatgta
     2401 aaagatggca atattgtatg tgtgggttgt ttaggaaatg gattaccaga agtttataca
     2461 gtagagaatg gaacattgtg taagaaaaca catttaaatg accatatttt agaggaatat
     2521 aaaatttctg tgccagaata catagagtca aaaggaagtt ctaaatggga aatacaagga
     2581 tacgtatata aaccagtaga ttatgaggtg gggaaaaaat atccagctgt attggcgatt
     2641 catggaggac caagattgac atatggacca tattttatgc atgagataca ggtatttaca
     2701 agtgcaggtt actttgtatt cttctgtaac ccaagggggt ctgaaggtcg tggcaatgct
     2761 tttgcagata ttaggaaaca gtttggagat attgattata tagattttat ggaatttaca
     2821 gatactgtac ttgaaaaata tacagacatt gataaaacaa aattggctgt tgaaggtgga
     2881 agttatggtg gatttatgac gaattggata attggtcata caaaccgttt tgctgttgct
     2941 tgtgctcagc gttctattgc aaactggagt ggcatggagg gtacaacaga cattggttat
     3001 tatttctgca aaggacaaac aggtgcttct catatggaaa accacgagct tcaatggaaa
     3061 cagtcacctc ttgcttatgc tgataaatgt gttacaccga ctttattttt acatggtgaa
     3121 aaagactata gatgctatat gcaagaagca ttccagatgt tttcagcatt gaaaattcat
     3181 gggtgtccta caaaactttg tctatttgaa ggagaaaacc atgaactgtc tcgttctggt
     3241 agaccaaaac aaaagctaca aagattagtt gaaatgctag attggttttc agtatatata
     3301 aaaaaagata acataggaca gtagaaagga gaatataaaa atggaaaaaa taaagattga
     3361 aaattcagat atttttgaat atatattccc tcatgatatt tcttgttcac ctgatggaaa
     3421 gcatattgct tatattatat caaatatcaa cgaggaaaaa gactgctatg aacatgactt
     3481 atatgtgatg gacatcaaaa cagaaaaaca aatacatatg actcaaacaa aagatgtaac
     3541 atcatttagt tggatttcta atacagaact cctttttaca tctaaaagaa ataagccaaa
     3601 atcaggtaca acagattttt acactatttc tatagaagga ggagaagcaa aaaaagcatt
     3661 ttctattcca aaagcttgta gcgtacctgt atcacttgga aataaattgt ggttactgac
     3721 aacaaaaaat ccaacggatt ctaaaaaatc agaaccagat agggcagtag agggtgtaga
     3781 ttattggaca tttacagata aaccttttat aagagatgga gaaaattttt ctcaaagaag
     3841 acgtgtaaca ttagaattat atcaagaagg tgaaaatata acaaaagcca ttacaccaaa
     3901 attttgtgaa gtagcaggtg tagacgtttc ttctgataaa aacagaattt tatatactgg
     3961 tcagatttat gaagattgtg caactccttt ttctggactt tgggagtatc atatagacag
     4021 tggtgaaacc aaagaacttg taccacaagg aaagtaccaa ataagtttgg caaaatatat
     4081 tggcaaagat aaagtaatgt tgcaagcttc aacattagac cgttctatca cacagaatca
     4141 tgatattttt atacttgatt tgagtactaa tgaaataaat atgattgcta gtccagatgg
     4201 tatgtatgct acattgctgg atgtagatgc agtatatggt ggtggacgta gtaataaagt
     4261 tataggagac aaatttattg gtgcaagaat ttgcagaact atgacagaat ttaatgagtt
     4321 tgatacaaag acaggtaata tacgtatcat cacaaaagta gatgctttta catcttttga
     4381 tatttacgac aacaccatgt acacagtaat gttgaaagat tatgagttag cagaaatata
     4441 tagcattgat atgactacag gtacaatgaa aaaaatgact gctttttcta aaccatattt
     4501 agatactcat aaggtttcat tacctgaaaa attgacgttt gtagcaaaaa ataaagaaga
     4561 agttgatggt tttgttatac cacctataga tgctaaagaa ggcgaaaaat atcctgctgt
     4621 attgttcatt catggtgggc ctaaatgggc atatggctat atgtttacac acttgaagca
     4681 gtgtgtaaca tcaaagggaa tgtatgtgat ttattgtaac cctcatggtg gtgacggtta
     4741 tggtgaaaaa ttcttagaaa tggtagaaag atgggggtat gttgactatg agcatcttat
     4801 ggaatttgta gatacttgta ttgaaaaata tcctgggatt gatgcagacc gcttaggggt
     4861 tgcaggggga agttacggtg gttatatgac aaactggata attggtcata cagaccgttt
     4921 caaagcagca gtttctcaaa gaggtattag taacttgatt acagcttctt taattattga
     4981 ctttggggat agaattatga agcagacttg tggagataag acgccttgga atcatgagga
     5041 ggttctttgg aatcattcac ctattaaata tgtgaaaaat gttaagacac caacattgtt
     5101 cttacatagt gatagggatt atagatgttt tatgggggat actttccaaa tgtttacagc
     5161 attaaaacag cttggtgtag atacagaaat gtatttgttt catggagata cacatggatt
     5221 gtctagaaat ggaagaccat ctaatagaat tgcaagagca aatgctattg tagattggtt
     5281 tgaaagatat ttataataag ggggttattc tatgagtgat atgttattat ggtttagtgt
     5341 cgtattagtt ttatttgcta ttggggattt aattgcaagc aaaacaaaag caaaagtatc
     5401 agctgtattt gttacactac ttttattttt gattctattt gtcacaaaag caataccagc
     5461 tgatattatt gaaaaagcag gtatgaccgc agcagctagt tggagtgttc caatgattat
     5521 gtttagtatg ggaacaatgt tgaatgttaa acaatttata gacgaatgga gaacagtatt
     5581 gacagcatgg cttggaattg tagcagttat agtctgtgtc tcattatgta ttcctttgtt
     5641 tggaaaatca acagtattga caagcatacc agttataaat ggagctttac ctgctactac
     5701 tattatgaca caagcagcac tagaaaaagg actgacactt gcagcagcta cagcaacagt
     5761 tgtatttgca attcagaagt ttattggtac accaatagct tcaagagcag cgttacaaga
     5821 ggcaaaccgt cttttagtag aatatcatga agcaaaatca aaaggcattg atttagcaaa
     5881 tgttgatact gataagaaag aagcagagaa tacaggcaca aaagtaaaac aagctttctg
     5941 tgaaaaatac gataaatatt attctacaaa tgtttgtata ttttttatag cattattctc
     6001 ttatctaggg tatgaacttt cagagattat tcatgtaaat tattctattg tatgtcttgt
     6061 tgttggtgtt attgtaacac gtattggtat tgtgccaaaa gacattttgg aaaaaggaaa
     6121 aatcaaggga tttatcaaca tggttgtgtt tgcagctgtt attccttctt tagcaaaagt
     6181 ttctttgaca gatttaatta gtctttttgt accaattgtg ggtatgtttg cagcttctat
     6241 cattggtata ttccttatga tgaaggtgtt accaggttgg aaaattatcg gttctaaacc
     6301 tcttgctttt ggagtagggt tttgtcagat gttgggattc ccaactacat atttaatttc
     6361 aaatgaagtg tgtaatgctg ttggagaaac ggaagaagaa agagcatatt tgatgtctaa
     6421 gattatgcct aagctggtag ttggtggtat ggcttgtatg atttctattg tggtagctgg
     6481 tcttatggta ccaatgttgt agataggttt catagttaaa aaagtggtat taatttatag
     6541 gagaagctaa aaagtagtat taatttataa aataatttta tattagttaa tttgttataa
     6601 gaatattttc tttttataat tataattttg attttataag atagcagatt ttttatttgc
     6661 tatgctaata gttataattt gtttttattt gctaaaatgc aactttaatt tgatttatgt
     6721 ataatatagg gtatttaata atatttttga agaattttta taaaaaatta aaaagaggag
     6781 aaaaaaggga gtgccacaaa gtgaactttt tagttctaag gcactctttt ttgtacgaaa
     6841 tcgaatatat tttcaacgtt ttaaaagtga gaaagagact tatctctagt ttgagatagc
     6901 caattttaat tattaaaatt attttttgtt ttatttatca aagagtattc gtgttttaga
     6961 agttagtatt ttttatttta tatatacaag gttttccgtt tctaatgttt tcttttttaa
     7021 aataattagg gtattcaatt atagtaaaag gtggatggta ttttggagtg atattattta
     7081 aagcacagta ttgaatgttg aaatcctcac attttagagt attatctttt gtaatcaaaa
     7141 aaatcttcta tacttatagc aaggttactt ctgcaaatat tccatacata ataatatccc
     7201 aatttaaatt t
//
LOCUS       DAEPKC010000142         7196 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.144, whole genome shotgun sequence.
ACCESSION   DAEPKC010000142 DAEPKC010000000
VERSION     DAEPKC010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7196)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7196)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7196
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.144"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            493..870
                     /locus_tag="KR294_003454"
     CDS             493..870
                     /locus_tag="KR294_003454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBH0241501.1"
                     /translation="MMIRKIPQAELKVMKFIWKVDVTVTSKDVIEAMEQKYGWKQTTT
                     LTLLSRLVKRGFLDAQKIDRYTHYTIRVKHKDYLSFETKDFLSNIHDDSLRSLISALH
                     DDENIGKDKLDFLESYFDNLKDE"
     gene            863..2011
                     /locus_tag="KR294_003455"
     CDS             863..2011
                     /locus_tag="KR294_003455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease"
                     /protein_id="HBH0241502.1"
                     /translation="MNNYMLYVFENLIKTTIVCSLGICLLLFLKRYLFKKFSKRFNYY
                     IWLIIVFRMLLFLFNYTIVYEVKEPKENALGNNITQIDISTDNNLMLYVAYLWLFVTI
                     VIAVYTFIKYTRFKNLVVDVSYDIEDNDINCIYKNLLKELNIKKKIELRGSDELISPA
                     GMGLFKSYIFLPDYPYSKDELTWILEHELMHFKNKDILIKFLVLSVRIIYWFNPLVYV
                     MSNKVNLDCELCCDESVLVECSLKDKKEYALALIKSIKFSKNYNSKILTTEFDKTNLE
                     KRLESIVKKKGKSGILIAVLVFMTSITSFVEVDAQVRIDEGNNGMNNNINEFLLNKTT
                     DKIINIYYKDAPNEIRKFYEDKCELEGKIPRDYDIIEMDMKDYNQLIK"
     gene            2028..2630
                     /locus_tag="KR294_003456"
     CDS             2028..2630
                     /locus_tag="KR294_003456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan-binding protein"
                     /protein_id="HBH0241503.1"
                     /translation="MLTKLRKIVAIMCCLLLTFTSVAFADTSKEKGGSKETVPEKNLD
                     SFTLSGYIYTYENAPQEIRDEHKQNCEEINIDPKPDDEIFVPESANLMNEDNSKGVYA
                     SYTVSYNIGAKTITIMSNEYLTISTTKVIRKGNSGKEVKAAQIMLTLLGYNVGIDSSF
                     GSKTYNAVVSFQKKYGLSADGIIGPATWDKLGRLTDPTLS"
     gene            complement(2723..3745)
                     /locus_tag="KR294_003457"
     CDS             complement(2723..3745)
                     /locus_tag="KR294_003457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HBH0241504.1"
                     /translation="MDYNDLLKSARENFNGTCKVCKICNGLACAGDVPGMGGKGSGSS
                     FIENRKSLEKIKINMRVIHNVSKPDTSIELFGRKMSSPIFAAPVSGTILNMGGKVSEK
                     EYIEPVVRGCSNSGIYAMVGDTNVDTFLLDNLDVLKDNRGNGIVFIKPWNNSKIIDKI
                     RLSEEAGAFAVGVDLDACGLINNQFQENPFSPKTIDEIRELVESTRLPFIIKGIMTVD
                     DALMAVESGASAIIVSNHGGRVLDYTPGTCEVLPDIAKSVKGKITILVDGGVRTGVDV
                     VKMLGLGADAVLMGRPFVTASFGGGLDGVEFFIEKVRNELCETMILTGCQNVKDIDGR
                     VIWNLL"
     gene            complement(4074..4256)
                     /locus_tag="KR294_003458"
     CDS             complement(4074..4256)
                     /locus_tag="KR294_003458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241505.1"
                     /translation="MYKDKSDECIHLMTAYIDSISGYYSFIDTQLEDFMMKYGENIVD
                     SNLHSIMMLLCKWGLS"
     gene            4569..4988
                     /locus_tag="KR294_003459"
     CDS             4569..4988
                     /locus_tag="KR294_003459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3785 domain-containing protein"
                     /protein_id="HBH0241506.1"
                     /translation="MSLYKFIYDDKEYLLKEENCSALINDEENPVQGVSISKIIDILN
                     EAEEVDFDVEYYQEACPLCLEGVKEKKKFFPFLEYHFYIFSKDGEYVISNISVDYKGL
                     SFNKLSRANKVDNSYIVSVIICENCQDYIVQIENCIV"
     gene            5119..6960
                     /locus_tag="KR294_003460"
     CDS             5119..6960
                     /locus_tag="KR294_003460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBH0241507.1"
                     /translation="MEEIDDTILDSMFKLTLNERLLTNNDFIENKIDVVKNLIDCYKT
                     EQNSLMLLKSNFLLALLYGIQGFSEKMKEYILISCKYIDKCLPKDYKFLARFYSQIAI
                     LSLKNEDVNKANLYMDKFNLICDENNFLIEEIIFKSQLIYIKASKCIESSVIIKEIET
                     LYIKIKEINDFNCKKIYFFIIGKIYFLFLDDALIAKVNFLKARKYADLLKDMQVSSLC
                     NIKIGECECSFENYECSMEYFNEVISNKKYRNVNIIQKYRASNNITKILIKTRNYPVA
                     INNLAKSEVYLEKIKNHSLKEVEKFDLFISLAMYYAKSNEKSFEQSICYLDRAKNILN
                     MIKNIEEYIIYDLEIIYHQAKIYYIFGYYDNALNTNKKLLEKSKNAKNYNYVKLAYKS
                     IYLCFEKIQNYEMSMKYFKMYYELKMMYIKARNRNYIDSLNYRHEYIEKEINNMRKVK
                     LDLDKKKYVDHLTSAYNRTFLNDFLEKQEVSEYCTAFMIDVDYFKEYNDTYGHYNGDI
                     ALKNITIIIKKYLKKDMLMIRYGGEEFLILSVCKDYKKSKIFGRKLCRIVKKFLNNNL
                     TVSIGIDTCKNSSIDIKEIIENADKALYKAKESGRNRCLHYHDFKNF"
     gene            6987..>7196
                     /locus_tag="KR294_003461"
     CDS             6987..>7196
                     /locus_tag="KR294_003461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBH0241508.1"
                     /translation="MKRSLIEDLKRNINKIEYDMLTKFYLNLTDLNYILDYHKDLLNT
                     KLEDNSRVYTLYLISLINYIKKDREA"
BASE COUNT         2945 a          765 c         1019 g         2467 t
ORIGIN      
        1 taaaataaag aactttatta gtagatatta aaagcacatt tttttataaa agtacttttt
       61 tataatttat gaaaggtata attataaaag tcttattcaa taaaatttat aattaattta
      121 gatatatttg taaataatca gtataaaata gatgttttaa tatcataaag gcataattag
      181 aaggttatta aaatttatta gatattactc tagtttattt taaaaaaaag tattataata
      241 ttccttgtgt gaaaatatag gaatttttat taaatagttt taatgtgtaa ataacattct
      301 acactattgt aattaaatat gtaaaaagta aaatatttaa atagatatat tttaaaatct
      361 aacttttaat attgtaaaaa aattagaaat ttaacaaaaa gtacaaaaat tcacattttt
      421 ttcataaagt gtttgactaa aaaattcaca tgttgtagaa ttaaggtagc aggagttttg
      481 agggaggtgt aaataatgat aagaaaaata ccacaagcag aactaaaagt aatgaaattc
      541 atttggaaag tagatgttac agtgacatca aaagatgtta ttgaagctat ggaacaaaaa
      601 tatggctgga aacaaaccac cacactgaca cttttatcta ggctggtaaa aagaggattc
      661 ttagatgctc aaaaaataga cagatataca cattacacaa taagagtaaa acacaaagat
      721 tatttaagtt ttgagacaaa ggatttccta agtaatatac atgatgactc tttaagaagc
      781 ttaatttcag cattacatga tgatgaaaat ataggtaaag ataagctaga ttttctagaa
      841 agttattttg ataatttaaa ggatgaataa ttatatgcta tatgtttttg aaaatcttat
      901 aaagacaact attgtatgta gtcttggtat ttgtctatta ttatttttga aaagatattt
      961 atttaagaag tttagtaaga gattcaatta ttatatttgg ttgataatag tctttagaat
     1021 gttacttttt ctatttaatt atacaatagt gtatgaagta aaagaaccca aagaaaatgc
     1081 attaggaaat aatattacac aaattgatat ttctacagat aataatctta tgctgtatgt
     1141 agcttattta tggttatttg taactatagt cattgcagtt tatacattta taaagtatac
     1201 aagatttaaa aatctagttg ttgatgtatc ttatgatatt gaagataatg atataaactg
     1261 tatctacaaa aacttgttaa aagaattaaa tataaaaaag aaaattgaat taagaggttc
     1321 tgatgaattg ataagtccag caggtatggg attatttaaa tcttacatat tcttaccaga
     1381 ctatccttat agtaaagatg aactaacttg gattttggaa catgaattaa tgcattttaa
     1441 aaataaagat attttaataa agtttttagt tttgtctgtt agaataatat attggtttaa
     1501 tccacttgta tatgtaatga gcaataaagt aaatctagat tgtgaattat gttgtgatga
     1561 aagtgttttg gtagaatgtt ctttaaaaga taaaaaagaa tatgcactag cacttataaa
     1621 gtcaattaag tttagtaaaa attataatag taagattttg acaaccgagt ttgataagac
     1681 aaatttggaa aagagacttg agagtattgt taaaaagaaa ggcaaaagtg gaatactaat
     1741 tgctgtttta gtatttatga cttctataac atcttttgtt gaagttgatg ctcaagttag
     1801 aattgatgag ggtaataatg gaatgaataa caatattaat gaatttttat tgaataagac
     1861 gactgataaa attataaata tttattataa agatgcacca aatgaaatta ggaaatttta
     1921 tgaagataaa tgcgaattag aaggtaaaat acctagagac tatgacataa tagaaatgga
     1981 tatgaaagat tataatcaat taataaaata attataagga ggattttatg ttaacaaaat
     2041 taagaaaaat agtagctatt atgtgttgct tattgcttac ttttacaagt gtggcatttg
     2101 ctgacacaag taaagagaaa ggaggaagta aagagactgt tccagagaaa aacctagatt
     2161 cttttactct ttctgggtat atatatacat atgaaaatgc gccacaagaa ataagagatg
     2221 aacataaaca aaattgtgaa gagataaata tagaccctaa gccagatgat gagatatttg
     2281 ttccagaatc agctaatcta atgaatgagg acaatagtaa aggtgtttat gcaagttata
     2341 ctgtttctta taatataggt gctaaaacta taacaattat gagtaatgag tatttgacta
     2401 taagtacaac aaaagttata cgaaagggta atagcggaaa agaagtaaaa gctgcacaaa
     2461 tcatgttaac tttacttggt tataatgtag gtatagatag ttcttttgga agtaagacat
     2521 ataatgcagt tgtaagtttc caaaaaaaat acggtttgtc tgcagatgga ataattggtc
     2581 cagctacttg ggataaattg ggtagactaa ctgaccctac tctttcatag gattaaaatc
     2641 taaaaatata ttaaatagtg tctcaatatg atttttcaat ttaaatgaga cactatttaa
     2701 atataaatgt tataaaacta ttttacaata aattccatat aactctacca tctatatcct
     2761 taacattttg acaaccagtc aaaatcatag tctcacataa ctcattccta accttctcta
     2821 taaaaaactc cacaccatca agaccaccgc caaaagaagc agtaacaaaa ggtcttccca
     2881 tcaaaacagc atcagcaccc aatccaagca tcttaactac atcaacacca gtcctaactc
     2941 caccatcaac aagtattgtt atctttccct ttacagactt agctatatct ggaagtacct
     3001 cacaagtacc aggagtataa tcaagtactc ttccaccatg atttgaaaca ataatggcac
     3061 tagcaccaga ctctacagcc atcaaagcat catctacagt cataattcct tttataataa
     3121 aaggtaatct agtggattca accaattctc taatctcatc aattgtttta ggagaaaaag
     3181 gattttcttg aaattgatta ttaataagtc cacaagcatc aaggtctaca ccaactgcaa
     3241 aagcacctgc ttcttcagac aatctaattt tatctattat ctttgaatta ttccaaggct
     3301 ttataaatac aattccattt cccctattat ccttcaatac atctaaatta tccagtaaaa
     3361 aagtatctac attagtatcg ccaaccatag cataaattcc agaattagaa caacctctaa
     3421 caacaggctc tatgtattct ttttcggaaa ctttaccacc catgttcaat atagtacctg
     3481 atacaggtgc agcgaatata ggagaactca tttttctacc aaataattct atggatgtat
     3541 ctggctttga aacattatgt atgactctca tatttatctt tattttttct agactttttc
     3601 tattttcaat gaaagacgaa ccacttcctt taccacccat accaggaaca tctccagcac
     3661 aagctaatcc attacaaatt ttacatactt tacatgttcc attaaagttc tctctagctg
     3721 attttagtaa gtcattgtaa tccatacaaa atctctcctt tttataatat taaaattgag
     3781 tattactata ttgaaaatat cttaattgta aatataggga tgttattatg atgagctaaa
     3841 ctagataata catattagat attttttatt gttgtagata gttaaattat atcatattag
     3901 atagtcaaat tttgaaaaaa actaacttat ttaagtatac attttgaaaa aattaaaaaa
     3961 gctatatata gatttttaaa gaaatctata tatagctttt aagtttatgt caatcttttt
     4021 tgttaatgaa taaataatat agaatacaat atacaaaaaa gtttcttgaa atgctaagat
     4081 aatccccatt tacaaagcaa catcattata ctgtgtaaat ttgaatcaac aatgttttca
     4141 ccatatttca tcataaaatc ctctaattgt gtgtcaataa atgaataata tccacttata
     4201 ctatcgatgt atgcagtcat taagtgtata cattcatcac ttttatcttt atacatatat
     4261 atctccccct atatacaata tataaattta gataccaaat cgtatcatat taaatagtta
     4321 agtgtgtaac atctatgcag ttatatattt atatcattat attaataact aaagtgagtt
     4381 ttgacaatag attttgggaa actggatgtt caaagtgcaa acttggattt taaaatcatt
     4441 aattaagata gcgcatagga atatatgtat acataactta attataaaga ttataaacaa
     4501 ttacttttat taactttatt taaatggtag aataacttgg agattaataa ttataaggag
     4561 gatataatat gagtttatat aagtttatat atgatgataa ggaatattta ttaaaagagg
     4621 agaactgtag tgctttaata aatgatgaag aaaatccagt tcaaggagta agtatttcaa
     4681 aaataattga tatacttaat gaagcagaag aagttgattt tgatgtagaa tattatcaag
     4741 aagcatgtcc attatgttta gaaggagtaa aagaaaagaa aaaattcttt ccttttttag
     4801 aatatcactt ttatattttc agtaaagatg gagaatatgt aataagcaat atatctgttg
     4861 attataaagg actatctttt aataaactat caagggcaaa taaagttgat aatagttata
     4921 ttgtaagtgt gataatttgc gaaaattgtc aggattatat agttcagata gaaaattgta
     4981 tagtttagtg taaagtatgt cttaatttaa gagaaatttc taaattgaga catcaacttt
     5041 tttcaaaaat agtatggaaa attactaaat ttatgagata atgtaagtcg gaggtgagtt
     5101 acaatatata gtaaatattt ggaagagata gatgatacaa ttttagattc aatgtttaaa
     5161 ctaaccttga atgaaagatt attgactaat aacgatttta ttgaaaataa aattgatgta
     5221 gtaaagaatt taattgattg ctataaaact gaacaaaata gtttaatgtt attaaaatca
     5281 aattttttgc tagctttatt atatggtatt caagggttta gtgaaaaaat gaaagagtat
     5341 attttgattt cctgtaaata tattgataaa tgcttaccca aagattataa atttttagca
     5401 cgattttatt cacaaatagc tattttaagt ttaaaaaatg aagatgtaaa taaggcaaat
     5461 ttatatatgg ataaatttaa tcttatttgt gatgaaaata attttctaat tgaagaaatt
     5521 atttttaaat cacaacttat ttacattaag gcaagtaagt gtatagaatc ttctgtaata
     5581 attaaagaga tagaaacgtt gtatataaag ataaaagaaa ttaacgattt taattgtaaa
     5641 aaaatatatt tttttattat tggtaaaata tattttttgt ttttggatga tgctctaatt
     5701 gctaaggtaa attttttaaa agcaagaaaa tatgcagatt tactaaagga tatgcaagta
     5761 tcttcactat gtaatataaa gataggtgag tgtgaatgtt cgtttgaaaa ttatgaatgt
     5821 tccatggaat atttcaatga agtaataagc aataaaaagt atagaaatgt aaatataatt
     5881 caaaaatata gagcatcaaa caacataact aaaatattaa taaagactag aaattatcct
     5941 gtcgcaataa ataatttagc aaaatctgaa gtatatctag aaaaaattaa aaatcatagc
     6001 ttaaaagaag tagagaagtt tgatttattt ataagtttag ccatgtatta tgcaaaaagt
     6061 aatgaaaaat cttttgaaca atcaatatgc tatttagata gagctaaaaa catattaaat
     6121 atgataaaaa atatagaaga atatataata tatgatttag aaataattta tcaccaggca
     6181 aagatatatt atatctttgg atattatgat aatgccttaa acacaaataa aaaactcctt
     6241 gaaaaatcta aaaatgctaa aaattataat tatgtgaagt tagcatacaa gagtatatat
     6301 ttgtgttttg aaaagattca aaattatgaa atgagtatga aatactttaa aatgtattat
     6361 gagttaaaaa tgatgtatat aaaagctcga aatagaaatt atatagattc cttaaattat
     6421 agacatgagt atatagaaaa agaaataaat aacatgagaa aagtaaaact tgatttagat
     6481 aaaaaaaagt atgttgacca tttgacaagt gcatataata gaactttttt gaacgatttt
     6541 ttagaaaaac aagaagttag tgaatattgc acagcattta tgatagatgt agattacttt
     6601 aaagaataca atgatactta tggacactat aatggagata ttgctcttaa aaatataact
     6661 ataataataa aaaaatatct aaaaaaagac atgcttatga taaggtatgg tggagaagaa
     6721 tttctgatat tatctgtatg taaagattat aaaaaaagta aaatatttgg aagaaaatta
     6781 tgtaggattg taaagaaatt tttaaacaat aatttgacag ttagtattgg cattgataca
     6841 tgtaaaaata gtagtataga tataaaagaa ataattgaaa atgctgataa agctttatat
     6901 aaagcaaagg aaagtggtag aaatagatgt ttgcattatc atgattttaa gaatttttaa
     6961 ctgttgaaat aggattggtg atttacttga aaaggagttt aatagaagat ttaaagagaa
     7021 atataaacaa gatagaatac gatatgttga ctaaattcta tctaaatttg acagatttaa
     7081 actacatctt ggattatcac aaagaccttt taaatacaaa attagaagat aatagtagag
     7141 tctatacttt atatttaatt agtcttataa actatataaa aaaagataga gaagca
//
LOCUS       DAEPKC010000143         6997 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.145, whole genome shotgun sequence.
ACCESSION   DAEPKC010000143 DAEPKC010000000
VERSION     DAEPKC010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6997)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6997)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6997
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.145"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(<1..1317)
                     /locus_tag="KR294_003462"
     CDS             complement(<1..1317)
                     /locus_tag="KR294_003462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PocR ligand-binding domain-containing protein"
                     /protein_id="HBH0241509.1"
                     /translation="MVDFIESNNEVQKFDWGEVMWIHEPSKTQFNRLSAGIVRFFPGN
                     CQEKHFHLSEEQLLYVIQGEGIQIIDGKKVNIKETSIVYCPPYSEHEIINTGKIDLVI
                     LITYVPHKFSSLRQIPIVFSENNIQELVNVNIIENLANQISNILKLRISVYDLKYKEI
                     FETKKENKFCDICKNIKPCTKKLVKSINNDNFEKVYHCEYGVSSLEIPIVLEENIVGY
                     IECGNFIVYKSIYIDKNLSELSSSSGIDIKYINKIYNEFPLNPKSRLYVLKENLLMMS
                     EFIQEIAKRNFFENQLSIKDEEILKSRKENIRLEEALKKANSRLLEEEYIINPIDMFN
                     NSSKEYPFELELYIEKEIKNMNLEGVYNLIDTNKLRYNDVRDTIQEMIFVLSRTVLRD
                     LEDLKLISYLRNKYNKKISLVNSDEDLWNVLFEFSKECIDKNRAFWR"
     gene            complement(2589..3668)
                     /locus_tag="KR294_003463"
     CDS             complement(2589..3668)
                     /locus_tag="KR294_003463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBH0241510.1"
                     /translation="MILITLCILVAVFVLAFAGLRLIAPTIIRTSHKIEAPGIDRMEM
                     VEIGGIQQALYIRGQNADNPIILWVHGGPGNSMMPFLHLYQYEWENDFTVVNWDQRNV
                     GKTYFANDPAAVLQTMSAERVLQDVHEVTAYLKQEFNKEKIILIGHSWGTVLGTMAVQ
                     TYPEDYSAYIGIAQTVNMVDNERVGYEKTLEMVKAAGKQKDIKALEAIAPYPPAKYGP
                     SYLAALMTVRTYQSKYGLSINMDLGNIISILATPYYSLRELKNTAIVNPNAIDNQGDV
                     LRFLVEEADIRNYGVDYQVPVYYIMGENDYNSPYLPAKKFFDEIVAPDKQIFFIPDAD
                     HLPFLSKKAEFDCVLLEEIAPKLAK"
     gene            complement(3752..4408)
                     /locus_tag="KR294_003464"
     CDS             complement(3752..4408)
                     /locus_tag="KR294_003464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH0241511.1"
                     /translation="MTRKNNPKQAIENIITISAKLFAEKGYDKTSMQNIVDASGMSKG
                     GIFHHFSSKEDIFNVVMERRFEQIIETVNQWLGEMHGLTAKEKLRSLVRRHLTDEVIK
                     ESSNMITSAIESPHIILAFTQDNLKKLAPILANVLREGIEDRSIITEFPDECAEVILL
                     LFNFWCDTDVFQGDFPTLRKRFQFLQFLMRQIGVDILEDEIIESINIFYERKPMGQVE
                     "
     gene            complement(5089..5517)
                     /locus_tag="KR294_003465"
     CDS             complement(5089..5517)
                     /locus_tag="KR294_003465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HBH0241512.1"
                     /translation="MSKIYIVYWSGTGNTEKMANFVAEGVKLKGKTPEVLDVSLLKPS
                     DLKEEDKFALGCPSMGAEQLEEGYMEPFVSELESMVSGKQIGLFGSYGWGNCEWMRDW
                     EERMQNAGATIIGGEGITAMEDPNEEAKDECIELGKTLAE"
     gene            complement(5993..6931)
                     /locus_tag="KR294_003466"
     CDS             complement(5993..6931)
                     /locus_tag="KR294_003466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family peptidase"
                     /protein_id="HBH0241513.1"
                     /translation="MNKRMKLIPYEINENLRGAKNKFPYGIKQMNARGMWDEGYTGKN
                     IVVGIIDTGCDISHPLLKGKIIGGANFSDDSNGNKNIYEDFNGHGTHVAGIIAASNYN
                     NEVMGVAPDCKLLIAKALNKDGTGTYQSIINAINFAVNNKVDIISMSLGGNKDDKNLK
                     NAVMQAVKNNISVVCAAGNNGDGDSSTSEYSYPASYAEVIEVGAINENYLVEKFSNSN
                     TTIDLVAPGRNIISTYMDNKLAIMSGTSMSAPYVSGSLALIKEWAREEFERDLDEAEL
                     YAQLIKCTRALGIPRTEQGNGYLYLNLYKYKNNSKR"
BASE COUNT         2180 a         1321 c          806 g         2690 t
ORIGIN      
        1 tctccaaaat gctctattct tatcaataca ctctttggaa aattcaaata atacattcca
       61 taaatcttca tcactgttta caagtgatat ttttttatta tatttatttc ttaaataaga
      121 tataagtttt aaatcctcta aatctctaag cactgttcta gacaatacaa atatcatttc
      181 ctgaatagta tctctaacat cattatatct taatttgttt gtatctatta gattataaac
      241 accttctaaa ttcatatttt taatttcttt ttcaatataa agttctaatt caaagggata
      301 ttcttttgaa gaattattga acatatctat cggattaata atatactctt cttctaataa
      361 tctactattt gcttttttaa gtgcctcttc aagtcttata ttttcttttc tactcttcaa
      421 tatctcctca tcttttatac taagttgatt ttcaaaaaaa ttcctcttag ctatttcctg
      481 aataaattca gacatcatta ataaattttc ttttaataca tataatctac ttttaggatt
      541 taatggaaat tcattgtaaa ttttgtttat gtattttata tcaataccag aactacttga
      601 taattcagat aaatttttat ctatataaat agacttatat actataaaat taccacattc
      661 tatatatcca actatatttt cttctaatac tataggtatc tctaaactgg aaacaccata
      721 ctcacaatga tacacttttt caaagttatc attatttatg cttttaacaa gttttttagt
      781 acacggtttt atatttttac aaatatcgca aaatttattt tctttcttag tctcaaatat
      841 ttctttatac tttaagtcat atacagatat tctaagcttc aatatattag atatttgatt
      901 tgcaagattt tcaattatgt ttacattaac taactcctgt atattgtttt cagaaaatac
      961 tataggtatt tgtctcaaac tcgaaaattt atgaggaaca taagtaatta atattactaa
     1021 atcaatttta ccagtgttta taatttcatg ttctgaatat ggtgggcaat aaactataga
     1081 tgtttccttt atattgacct ttttaccatc aattatttgt attccttctc cctgaatcac
     1141 atataaaagc tgttcttcac ttaaatgaaa atgcttttct tggcagtttc ccggaaaaaa
     1201 tcttacaatt ccagcactaa gtctattgaa ttgtgttttt gatggttcgt gtatccacat
     1261 aacctctccc caatcaaatt tttgtacttc attatttgac tcaataaaat ccaccataaa
     1321 ctcacctcgt agtttttgtc taaatatttt ttcttccctt cttatattaa aataatatca
     1381 tcatcattaa ctttcattac tataaaatca tcatactctt ttaatactcc tgtaatttta
     1441 gttgcactta gtttactaca attcagtttt ttaatatatt gataaattct ataattactt
     1501 ttttattttg taaaatcagt gttttcccaa aataattata tctataaatg aaagtatttt
     1561 tactgcttac atcaatatat gttatcataa ttttcctttt tattgcatat ataaataact
     1621 gtatataaca ttgtccaata ctatatagaa atacatctaa gaaagaatat tattaaattg
     1681 ttccaattaa tattattttt cttatagaaa taaaaaactg ttggattctt ttagaaaaat
     1741 tattttttac ataccttttt tgcttaaata gtctatcttc tcagctattt tgtatataca
     1801 ctcttctagt tcatgatttt attttaatat cttgcttata ttgctgaaat aattaaattc
     1861 ttttatctat catattgtct cttatatcac aaacatattg tttcttatat cacaaaaatg
     1921 aaagcattct tatatcttca atatataaac ctgctttttt taatcttgta ataaatatag
     1981 gatactctat attctcttcc tagaaataac taataccact tatttttcta tcatatagaa
     2041 agtaataaat ctttttctta ataaaattca atagtaagtg gaataaaatt ttatatgaat
     2101 aagaacatta taaaaatact ttatacaata gtcaataaaa gatattagct tcaaattgtg
     2161 ttgaagttgt attatttaaa gtggaaaagc aaataaaaaa gaaataatgg tataagtaga
     2221 aaaatatact taaaacaagg cgaagcctct cttgtatcta aatcaagtag agaattaaat
     2281 ctaaaaaaga aaataaatat aaaagatgac tcctgtacat tacaagaatc atcttatggt
     2341 ttcataatca ctccatggtt tttaactgtc tgatataaag gtctcagttc actcatagca
     2401 tgaccacctt ttccgattgc tgaccccgtc acttatggac aaaatgtcca taagtgatag
     2461 tcctctctta aaaccctcta aatagatata tctcaagcac ctcattgaaa ccagttgctg
     2521 gaaacaaact gaagcgttct ggaatagtaa aagaaattgc caccatatcc acgttactgt
     2581 cctagttgtt actttgctaa cttcggagcg atttcctcta acaatacgca gtcaaattct
     2641 gcctttttgc taagaaatgg cagatggtct gcatctggta taaaaaaaat ctgtttgtct
     2701 ggcgccacta tttcatcaaa aaatttcttc gctggaagat aggggctatt atagtcattt
     2761 tctcccatga tgtagtatac agggacctga tagtcaactc cataatttct tatgtcagct
     2821 tcttccacta aaaaccgcaa tacatcacct tgattgtcaa tcgcatttgg attgacaatg
     2881 gccgtatttt ttaactctct caatgaataa tatggggttg ccagtatact gattatattg
     2941 cccaaatcca tatttataga aagcccatac ttgctttggt atgttcttac tgtcataaga
     3001 gctgccaaat agcttggacc atattttgct ggcggatatg gtgcaatagc ttccagcgcc
     3061 ttgatatctt tttgcttccc tgcagctttc accatttcaa gtgtcttttc atagcccacg
     3121 cgctcattgt ccaccatatt aacagtctgc gcaatcccaa tgtacgcgct gtaatcctcc
     3181 ggataggttt gcacagccat agttcccagc actgttcccc agctatgacc tataaggata
     3241 attttctcct tgttgaactc ttgcttcaaa tatgctgtca cctcatggac gtcttgcaga
     3301 acacgctccg cgctcatggt ctgcaaaact gctgccggat cgttcgcaaa gtatgttttg
     3361 cctacgtttc gctgatccca gttcaccaca gtaaaatcat tttcccactc atactggtac
     3421 agatgtaaaa atggcatcat tgaattacca ggacccccat gaacccaaag gatgatgggg
     3481 ttgtctgcgt tttgtccccg gatatataac gcctgctgta tgccgccgat ctccaccatt
     3541 tccatgcggt cgattccagg agcttctatt ttatggcttg tacgtataat cgtgggggct
     3601 atcagacgca aaccggcaaa cgccagaaca aaaacagcaa ctagtatgca aagtgtgatt
     3661 aatatcattt taagtacctt ctttcatgaa tttttttagc catagatatc tcctctaaca
     3721 ttaaaaaaag tatgttgcta ttttagtttt gttactctac ctgtcccatt ggtttccttt
     3781 cataaaaaat attaattgat tctataatct catcttccag gatatcaact cctatttgtc
     3841 tcataagaaa ctgtaagaat tgaaaccgtt tacgaagtgt aggaaagtcc ccctgaaata
     3901 catctgtatc acaccaaaag ttaaagagca gcaaaattac ctctgcgcat tcatctggga
     3961 actctgtgat gatgcttcta tcctctatgc cttctcgtaa aacatttgct aatattggtg
     4021 ctagtttttt caaattatcc tgtgtaaatg ccagtatgat atgcggactt tctatcgcgc
     4081 ttgtaatcat gttactagat tcttttatca cctcatccgt taaatgccgc ctaactaaac
     4141 ttctaagctt ctcttttgct gtaagtccat gcatttcacc gagccattga tttactgtct
     4201 ctattatctg ttcaaagcgc ctttccatga ccacattaaa aatatcttct tttgaactga
     4261 agtgatgaaa aattccgccc tttgacattc ccgaagcatc aacaatattt tgcatacttg
     4321 ttttgtcgta tcctttttca gcaaacaact ttgcagaaat ggtaatgata ttttcaatag
     4381 cttgctttgg attgttcttt ctagtcatta tataactcct tcttattaaa aaccgactgt
     4441 tggtttttat tatataagct attcctgctt ctgtcaagta acattgtgtt tatggcaaaa
     4501 caataaggtt tggtggttag acaggtatta attagactaa tgcgactttc ccctagatgg
     4561 aacccttggt aaatttgcaa tctttaccgg ctttgattat atctgtaagc aaggcaggta
     4621 tggccacgcc tgccctgttt gaccctcgga tattcattcc tatccctcct ctccttagcc
     4681 attacaccaa aacgccgctc attgtctcca atggcggcgt tttaaagata tgatttctca
     4741 tgctgctgaa atatgcaaaa aatataagat gccctttatt atttttccta caatagaaaa
     4801 gaaaagtatt gaagaatggg ttaatattgg agcaaatatg ctttgttttg cacaagatac
     4861 tacctttatc acttatgtta tcaatcaatt attatctttt tataatgaga ttgtaccaat
     4921 tcaaaaacaa cattaaatta taaatctaat tttatattaa aagagactaa tattttatct
     4981 atctctatta aggatatttt cttatgtatc ataatattag tctctcttat tattatatac
     5041 tgctatcatc attagttgtt atttatacta tttttataat atacaaattt attcagctaa
     5101 cgttttgcct aattctatac actcatcttt tgcttcttca tttgggtctt ccattgctgt
     5161 aattccttct ccaccaataa ttgtagcacc agcattttgc atacgttctt cccagtctct
     5221 catccattca caatttcccc atccatatga accaaataat ccaatctgtt tacctgatac
     5281 catagattct aattctgaaa caaatggctc catatacccc tcttctagtt gctctgctcc
     5341 catagatggg caacctaatg caaatttatc ttcttctttt aaatcacttg gtttcagtaa
     5401 gctcacatct aaaacttctg gtgtcttacc ttttaacttc acaccttcag ccacaaaatt
     5461 tgccattttt tcagtatttc ctgttccact ccaataaaca atatatattt tactcatttt
     5521 tacctcctgt agtatttttt aattaatcaa tagttagtta tagctaacta acatctaaaa
     5581 aacaaaagat ttctttatct gaaatctctt tatttttcta aatatagaat atcatagttg
     5641 atattgaaat tcaatactta ttgataatat ttatcattta tattttatat tcattttata
     5701 atatcaaaac actgtatcgt atttctaatc tttcatagaa aaatttctaa cttatagtac
     5761 ttttgcatct cttataaatc ttttatatgt ataagtacat agaaaaacac accttttcca
     5821 gatgtgctat ctataatatc gtatatttat ttttcaattc taactagcta atatgtttat
     5881 aaattttatc acttaatacc tttatacatt gatgtaaaat cttacaccta agtaattttt
     5941 attatttgtc tcgactctat ataatatagc tattttatca tcaaatcaaa aattatcttt
     6001 tactattatt cttgtattta tagagattta aatataagta tccatttcct tgttccgttc
     6061 taggtattcc aagcgctctc gtacatttta ttaattgtgc atacagttca gcttcatcta
     6121 aatctctttc aaactcctct cttgcccatt ctttaattag tgctaatgag cctgatacgt
     6181 atggtgcact catactagta ccactcataa tagcaagttt attatccata taagttgata
     6241 taatatttct tcctggagct accaaatcta ttgtagtatt tgaattacta aacttttcaa
     6301 ccaaatagtt ctcatttatt gcacctactt ctattacctc agcataactg gctggataac
     6361 tatactcact tgtactagaa tcaccatctc cattattacc tgctgcacac actacagaaa
     6421 tattattttt tactgcttgc atgacagcat tttttaaatt cttatcatct ttgtttcccc
     6481 caagagacat agatataata tcaaccttgt tatttacagc aaagttaata gcattaatta
     6541 tactttgata tgttccggta ccatctttat ttaatgcttt tgctattaat aatttacaat
     6601 ctggagctac tcccataact tcattattat aattagatgc agctataata cccgccacat
     6661 gagttccatg accattaaaa tcctcatata tatttttatt tccattactg tcatcactaa
     6721 aatttgcacc accaattatt tttcctttta aaagaggatg agatatatca caacctgtat
     6781 ctattatacc aactacaata tttttaccag tataaccttc atcccacatt cccctagcat
     6841 tcatttgttt tattccatat gggaatttat tttttgcacc tcttagattt tcatttattt
     6901 catatggaat tagtttcatt cttttattca tcatatatcc tcctaaaaat tttattgctt
     6961 ataaaaatca tgaattttat tttataatag gtttata
//
LOCUS       DAEPKC010000144         6852 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.146, whole genome shotgun sequence.
ACCESSION   DAEPKC010000144 DAEPKC010000000
VERSION     DAEPKC010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6852)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6852)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6852
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.146"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(1035..1244)
                     /locus_tag="KR294_003467"
     CDS             complement(1035..1244)
                     /locus_tag="KR294_003467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241514.1"
                     /translation="MHINQTGFISNGLGIKQQQKKEPTSNSFSYNAPSSWKPVGRDSV
                     QYNCGFESIATLVRGGSSWSFNFIV"
     gene            complement(1441..1770)
                     /locus_tag="KR294_003468"
     CDS             complement(1441..1770)
                     /locus_tag="KR294_003468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241515.1"
                     /translation="MNYRLKKSVTTILSLLIMTILLPTNASASKVEDSSMKVMYSEKQ
                     VTDMDKLYDMAKNGITDVKSSNEKGIIKNARTGESIYVDSISTTQLLEVKQSKNLTSK
                     IYSKTVF"
     gene            1897..2280
                     /locus_tag="KR294_003469"
     CDS             1897..2280
                     /locus_tag="KR294_003469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241516.1"
                     /translation="MRKKFFIGILIVLIISVIAILNIKNDKNVFIGESENWKAKFVTT
                     EGHSKLEIKYKNSKDVVEQKFNYSYQFIDGEDAVVVVKNEILEAGQEKAIKIQRPGLY
                     SNRESSYKLIISWNGNEETINLKKK"
     gene            complement(2649..2858)
                     /locus_tag="KR294_003470"
     CDS             complement(2649..2858)
                     /locus_tag="KR294_003470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241517.1"
                     /translation="MMGLKLKRRYKNVLIYINIRTIININCKIKFIELYLTFNELKNK
                     LANNEKTTVINENNKAFSGLVDFSN"
     gene            complement(3500..3751)
                     /locus_tag="KR294_003471"
     CDS             complement(3500..3751)
                     /locus_tag="KR294_003471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241518.1"
                     /translation="MSSYFITRGDVMKILQQFKPYKYDKEKNIEYDEKIIANQNTEVY
                     IVYPRISDEENRRRWEEFNEVAKEVAINIAMKKVETVES"
     gene            complement(3997..4152)
                     /locus_tag="KR294_003472"
     CDS             complement(3997..4152)
                     /locus_tag="KR294_003472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="regulator"
                     /protein_id="HBH0241519.1"
                     /translation="MALEVKIEVKIIKDVVILNITHWKKETSLLTVKIARGQGDLSYV
                     KYFTNES"
     gene            4831..5055
                     /locus_tag="KR294_003473"
     CDS             4831..5055
                     /locus_tag="KR294_003473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0241520.1"
                     /translation="MDVNQRIKYIRENMNSSQKELLEKTNINTSVMNRIESGERPTRE
                     DGLIIFAKIFGLYTDYILGLSDTEKLNIGN"
     repeat_region   5342..6490
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=5407..5435
                     /rpt_unit_seq="ctttacataccacttagttaatataaaac"
BASE COUNT         2535 a          952 c          715 g         2650 t
ORIGIN      
        1 taatattata ttacttagtt agaaagagat atataactat ataaaatcta atagaattaa
       61 tatcaaaaga aggtagcaac taatcaccag caattaaaat aatttgtttt tcaaagttaa
      121 taaaagtctt ctttatagca atgatttaaa tataatcaaa tatcgtaacg gagatttttt
      181 tatgaataat ttaagaaaac aattaatcaa agaaattata taagatggag aacttataaa
      241 atctacagat ataagtagtt ttaggagtaa acacagatga cttatttcaa agagacaata
      301 gctacaagtt atcctcattc tgtaatacaa aaatgtttaa tacattagat aagaaatact
      361 ttaaatatgt ttcatacaag gactcaaaag aattaataag taattttaaa tctgtatata
      421 ggtcagttaa tgaataagaa gccttatcga ctttagataa aatagattaa aaataatgta
      481 aacagtatac ttcagaaatt aaaattttgg gaaataactg gaatgttgta gcatcatcct
      541 ttagttttac taaaataagt aatatctata atatatatta caagtataat cgaaagattt
      601 aataaatatt tcaaaaatgt ctcaaaaaca aagtccagat ttacatcaaa cgcttcactc
      661 ttaaagatat tattcttgac aagcgaaaat gtgatgaaaa aatggactat gaaatataaa
      721 aattgatata atatatacaa tcatttattc atatcttttg atagtagaat ataattttaa
      781 aaattatacc ctaaaaattt gctataattg ttataatata tataatttcc aaaaatattt
      841 aaaaacatcc caatatacat tctttataat ttgttaaaat aaaattcata tattaagaaa
      901 tattaatagt aaataagcaa ttgttgctat aacttaggaa ttatctttaa aaacacaaat
      961 taatttacat tttctaattt taaagtatat gtatatcttt aattttaata aaattcactt
     1021 aaaatatttt aaggttaaac aatgaaattg aatgaccaag aacttcctcc tcttactaat
     1081 gttgcaattg attcaaaccc acaattgtat tgaactgaat ctctacctac tggtttccaa
     1141 ctagaaggtg cattatatga gaaagaattt gatgttggct ctttcttttg ttgctgctta
     1201 attcctagcc cattagaaat aaatccagtt tgatttatat gcacccttct atttgttaca
     1261 cgaatctggc cgtctgcaat agaccagttt ccagaaactt tactaacgga aatatattga
     1321 aatgctccat ctccttttga tattgtatat gtaactgtac cagatgcttt tacaccacca
     1381 gttttatccc atccatcttc tgatatactt gcttttctaa gaggctttat tgtattagta
     1441 tcaaaaaact gtcttagaat atatctttga tgttaaattt ttagattgtt taacttctaa
     1501 taattgagtt gttgatatag aatcaacgta tatggactct cctgttcttg catttttgat
     1561 tatacctttt tcattggaac ttttaacatc agtaattcca tttttagcca tatcgtataa
     1621 tttgtccatg tctgttactt gtttctctga atacattact ttcatagatg aatcttctac
     1681 cttactagca cttgcatttg ttggtaatag tattgtcatt atgagtaaag ataaaatagt
     1741 tgttacagat ttttttaacc tataattcat attaatccct actttttatt tgttataaca
     1801 gacattctat tgtaatagaa tataaatcca caatattttt aaaattagta ttgaataact
     1861 attctcatgt tataattatt caaaggaggg attgatatga ggaaaaaatt ttttataggt
     1921 attcttatag ttttaataat ctctgtgata gctatactta atataaaaaa tgataaaaat
     1981 gtctttattg gagaatcaga aaattggaaa gcgaaatttg taactactga aggacactca
     2041 aaattagaaa taaaatataa aaatagtaaa gatgtagttg aacaaaaatt taattattcc
     2101 tatcaattta tagatggtga agatgcagtt gtagttgtaa aaaatgaaat tttagaagca
     2161 ggtcaagaaa aagcaataaa aatacaaaga ccaggtcttt attcaaatag agaatctagt
     2221 tacaagctaa ttatatcttg gaatggaaat gaggaaacta taaacttgaa aaagaaataa
     2281 ccatattatc aatttttaaa aaattattat tcaaattctt ataaaaagag tgtttagaaa
     2341 aatgaaacac tcttttttgt ataagttttt gaaaactata aatgaaatat atcaaaatcg
     2401 ttcgaaaaat tactgaaata aactcttaaa tatattataa attaaggtat attatacatg
     2461 aatttattgg gagtttatga gttttaaaat tggaaaccaa acaataaggg cgaaaaatac
     2521 ttcaaggaaa atatataaag ttctataaat tatcaaaaat atttcgcaaa aactgataat
     2581 tattacaaat aaattgataa tactaataat attagaaata tcgaaattga acaaactagg
     2641 attaaagctc aattagaaaa atccactaat cctgaaaatg ctttgttatt ctcatttatt
     2701 actgttgttt tttcattatt tgctaactta tttttcagtt cattaaatgt taaatataac
     2761 tctataaatt taattttaca gttaatattt attatagttc ttatatttat atatattaat
     2821 acatttttat atcgcctctt caatttgagc cccatcatta tataaaatta acctactgga
     2881 tatcttaatt taatatatgt acactattca tatcttaata gtcaatatta ttcattttta
     2941 atagctcttt ttagatgtca gaattattat attttgaaat ttattaaatt tttgcattaa
     3001 aaaaactaga aattaattta agtcttgaat tacttataac tttctacgta tctaccttta
     3061 tattcttact ctgattttat atctaatatc aactcttcat caaagctatt aaatatacct
     3121 ctaattgagt caattatttc acttacttca cctttaattt ttatattaac ttcaaccatt
     3181 tcaaatctca tctttttatc ttataatttc tataagtttt tttatttatt gtgttgctta
     3241 ctttgaccag cactttttta tttaatagtc taaatgatat tttttaccag ttttaatatc
     3301 cttaaatact atatttacta aaaacttata atttctttta atacatagtt aatacattct
     3361 tattactaat aacaatactc aacaatttta tcgccttttt tcaaatatga tttaactttt
     3421 ttattcctaa ttatttaaaa atagttgtcc aattttcttc tatgagaaag tgctaagtat
     3481 tagcaacttc tctattctct taactttcta ctgtctcaac tttcttcata gctatattaa
     3541 tagctacttc tttagctact tcattgaact cttcccatct tctcctattt tcttcatcag
     3601 atatacgtgg atatactata taaacttctg tgttttgatt agctataatt ttttcatcat
     3661 attctatatt tttttcttta tcatatttgt atggtttaaa ttgttgtagt attttcataa
     3721 catcacccct tgttataaaa tatgaactca taaacttgtc ttatacttat ttaattgtta
     3781 caatttttac ttaaaatcac tttatattct atatattaaa gctaaatcct ttacaaaagt
     3841 aacatattct tctataagtt tcttatcctc ttatatagta tctagtttgt ttaacttatc
     3901 tcttttaaac ttacatacgc cttcttctgc cattcgtctt ttattaattg ttaacattat
     3961 ttcaatagac acaccaaaac tcttgttaag aagctcttag ctctcattag taaaatattt
     4021 tacataactt aaatcacctt gacctctagc aattttaact gttaatagac ttgtttcttt
     4081 tttccaatgt gttatattta atataacaac atcttttatt attttaactt ctatttttac
     4141 ctctaatgcc atattattgc ttgattaatt tgtatcctta aatattaaat tttctattaa
     4201 tacatcttct atacagctta gtttctctcg cttaatcttg aaatatattt tctctaaatt
     4261 gtcaaattgt tctcaagttt tatcaatatc taatattttg cagtgtctat ttgcacatct
     4321 ttcggtccaa atgtataatt gactagaatg ttttgaaatc aactgactat tagtaggtta
     4381 gttcttaaat tctttcaaat actcgaattg taataaaaca taatttacat tctctttatt
     4441 tctattgaag ctagtttata tattgtttac atcattttca tatatatctg ctagttgcta
     4501 tgtatttaaa attctcttat tatttcttta tattacttgt aaattattca tccttatcat
     4561 cctcttaatt aaattttcta tatcataatc aagtatctta gatagtttat aggtaatata
     4621 tcaactctaa ttgaatatta ccctttcctg tacttaaaat aagttgatgc atttttaaaa
     4681 cctaactctt ttgcaacact ttgtaagtat aaattttatg tatgtcttct tttttataaa
     4741 atcatagtgt atctttttca tatattcaca ttaatttcta tatttcaata acaatatttc
     4801 caaagcagaa acttttcgag ataattatgt atggatgtaa atcaaaggat taaatatatt
     4861 agggaaaata tgaatagttc tcaaaaagaa ttgcttgaaa aaacaaatat aaatacaagt
     4921 gttatgaata gaatagagtc tggtgaaaga ccaacaagag aagatgggtt aataatattt
     4981 gctaaaattt ttggtttata tactgattat attcttggtt tatcagatac agaaaaacta
     5041 aatattggca attaaaactg aattaattgt attatatgtg tgatgaatat aaatagagaa
     5101 ttttttgaaa agcttgaaat aacttagaaa aaataagagg ttcactcaag aacaagttgc
     5161 taaagattaa aaaacaacaa aggtatctac taaaagatat gaaaatagtt taagagagtt
     5221 gagtctggaa atatttatgt gtattcttta aataaaaatt tattttttaa atgataatta
     5281 aatttttact gatatggcta tgcttttaaa agtcctaacc ttattttgac attatatctg
     5341 tctttacata ccacttaatt aatataaaac agtataaaaa ttagttacag atgtatcttt
     5401 tttgttcttt acataccact tagttaatat aaaactttgt ggatgtaagg ctcaaagtta
     5461 cgaagaaaaa acctttacat accacttagt taatataaaa caaatatctc tagcaacatg
     5521 aagtgacttg ccagaaccct ttacatacca cttagttaat ataaaacatg agaaacaaaa
     5581 tattaaaatt gataatatta ttgcctttac ataccactta gttaatataa aaccagtcca
     5641 acgttgcacg gtcgtaacgt gtcaatccta ctttacatac cacttagtta atataaaacg
     5701 ctaaatggag caaccgacta agtcgctaga aatactttac ataccactta gttaatataa
     5761 aaccggctat gaatttgaac atataagggt tacagataag tctttacata ccacttagtt
     5821 aatataaaac ttgctgtaag gctgttcgtt acagggatgg cagagtcctt tacataccac
     5881 ttagttaata taaaacaata acgaagctag aaatctttat tcagcgatta caagctttac
     5941 ataccactta gttaatataa aactatgcgt gaaatatttg tttaggaggt ttatttttac
     6001 tttacatacc acttagttaa tataaaactc tcatgatatc tgtaaacttt tcccataatt
     6061 ttccctttac ataccactta gttaatataa aacatagatg tttcaatttt tctttgatat
     6121 tgtaaagctc tttacatacc acttagttaa tataaaacca tagttcttaa gttcttcaga
     6181 actattcaag tgcaacttta cataccactt agttaatata aaacaagacc caactggtac
     6241 tatgtaaaca atttatcctc tctttacata ccacttagtt aatataaaac tttaattatg
     6301 aatgataatc atgttacaga gaaacaaact ttacatacca cttagttaat ataaaactca
     6361 catattcttc tatctatatc acttaacacg tcaaacttta cataccactt agttaatata
     6421 aaaccaaatg aatttctacc aagaatagca ggttttattg cctttacata ccacttagtt
     6481 aatataaaac cccaaaataa attgagtatt tccaacactt acatctatac aattctctca
     6541 aatttgcagt gaaccacgag tagtgcaaat gataatattt atcatatacc ctcaatgcct
     6601 tatgtttcaa ctgttaagcc ctattttatc aaaaatatcg ctcactgcaa aactatttat
     6661 aatattatga atatattatt tttaaatatc tgtaccaatt tgtagtataa taaaatcaag
     6721 aaaataattt actcctataa agagtgatta tttttaagtg aaaatattat ttttttaaat
     6781 cattcttatt ggcgtttggg agatttttat tttatcataa atataaactg atataacacc
     6841 agctgacatg ct
//
LOCUS       DAEPKC010000145         6700 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.147, whole genome shotgun sequence.
ACCESSION   DAEPKC010000145 DAEPKC010000000
VERSION     DAEPKC010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6700)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6700)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6700
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.147"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            277..798
                     /locus_tag="KR294_003474"
     CDS             277..798
                     /locus_tag="KR294_003474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBH0241521.1"
                     /translation="MEEIVKKEQASMNDIFLYLKAKSNSLYKFVILYNEFINKPKDYG
                     TGELINMVEVHMLTAIEENPGISPTQLAKIWNRTKGAISQTISKLEKKGYITKEKKEG
                     NAKTILLYPTTSGVELSKAHKLYDTIDVTRTFEYLIKECTLEEIDSFYKVIDLFINLL
                     EESPQENNDSEKV"
     gene            1177..2352
                     /locus_tag="KR294_003475"
     CDS             1177..2352
                     /locus_tag="KR294_003475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH0241522.1"
                     /translation="MNLKQLSEKYEEYVIQMRREFHKYPELSFKEIRTTQRIREELQK
                     IGVPFVSIEPNIVIATIQGKNEGKTIAIRGDIDALPMQEDSDVEYKSEYDGIMHSCGH
                     DAHGAMLLGLAHMLNDIRKDLKGRVLLVFQAAEEVGGGHKEIIQYFKENGGPDRLIAT
                     HVWSDIEAGKISVEPGPRMAGGSGWRIDITGRGGHGSRPDQSIDPIKPACDIVLKVSS
                     IPVNHISVLEQCVVHACAIHGGTTIGNVIPNNAEVIGGYRYFTEESGKKVFDIIKQMS
                     NGVGQVYGVDVKVTHTGGIGPVINDEEAVKMAKEIVSNIDGLELDSYEPICASDCYGE
                     ILKEYSGFYCYLGVGNKEKGIIYAQHHPKYNIDEDILKLGCEFMAKYAVEFLNKNNN"
     gene            2386..3924
                     /locus_tag="KR294_003476"
     CDS             2386..3924
                     /locus_tag="KR294_003476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbgT family transporter"
                     /protein_id="HBH0241523.1"
                     /translation="MQGALKENKKKSGGGFLGWIEKVGNKMPHPLALFTYITLIVVAL
                     SAIASFLGFSATSPATGKLIKVMNLISAKGLVLFMQEFVKNFQNFPVLGVVLVMAVAT
                     GVCEKTGFFSTAIKMSLSKVKGNAVVFIIAFIGVFANQAGDAAFVLVPTLAGAIFYGL
                     NRNPLAGIFCGFASVGGGFATAVIPGGWDVTLTPITVSAAQTIQPAFDMTLLASYYAL
                     FVSAFIVATVSTIVTVKFIEPKLGKYTGKPEGIDDNQGFEVTKEQAKAAKLAGFTVLA
                     YVALLIALCIPANSFLRSPEGSLIFGAPLMSCLQFFIVILFFLPGIVYGMRVGKIKTV
                     KDLNDILCQSMAAMAPFIVLAIVIGQFLTLFSVSNLAQVLAIKGGALLNSLPLPPQAI
                     ILLFLVLVAFINIFVISGSTKWMIFGPVFVPMLMQLNIHPAFTQFVYRLGDSVTNHLS
                     PLNAFFIILLATVQKYDKNAGMGTIFSAMIPYTIGYFVVLAVLVVVWMTIGIPVGIGG
                     QVWL"
     gene            3956..5158
                     /locus_tag="KR294_003477"
     CDS             3956..5158
                     /locus_tag="KR294_003477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBH0241524.1"
                     /translation="METTEIRYNFDEVIDRSGTNCLKYDLKSQFMPESPEDALPLWVA
                     DMDFACAPEIINAMHERIDRKIFGYSSQQTDDYYEAVCGWFKRRFDWKIEKENIFFSP
                     GVVPALGFFTQILTQKGDGIIIEKPVYYPFEDKITNNERKVVNSPLKFEDGHYSMDYD
                     GFEELAKDENNKVFILCSPHNPVGRVWKKEELRKIVDICKKYDLWIISDEIHCDIIRK
                     GEKHIPLEVACPDYKDRIITCTAPSKSFNLAGMQLSNIVINNKELQEKWMLETDSKLA
                     IFLPNPFAIVATKVAYNDCEDWMNQVNEYIDGNIKYVEDFVNEYMPKVKIIKSQGTYL
                     VWLDFRGYGLDAKQLEYVMLNKAKVLLDEGYIFGEEGAGFERINVASPRTIIEECMNR
                     IKCAFEGL"
     gene            complement(5325..5924)
                     /locus_tag="KR294_003478"
     CDS             complement(5325..5924)
                     /locus_tag="KR294_003478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH0241525.1"
                     /translation="MNDNIVEVKNINMNFYTKEGELEVLKDVNFNLKEGEILTLLGPS
                     GSGKSTILNILTNLLKPTSGDIKITGNIGYMFQKDNLLEWRNIMDNITIGLEIQGKKD
                     KKSLDRVESLLKTYGLWDFRSMYPKELSGGMRQRVALIRTLSVNPDILLLDEPFSALD
                     YQTRLLVCDDVYSIIKNENKSTILVTHDIGEARCIKVQL"
     gene            6094..>6700
                     /locus_tag="KR294_003479"
     CDS             6094..>6700
                     /locus_tag="KR294_003479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241526.1"
                     /translation="MSNIITNLIESIFTNPITILFLLAITVYSVFKIIENNRVYSFVS
                     SKLDEINRDYKTSEFYKKVRDDYYTYSKENPYADVNITSFIEEVVSDLKHNNLPLLEK
                     IRSIKNSSSISILLGVLGTFVGLSTMLLCVDTKDIINSLPSTISSMQTAFTTSIFGVV
                     FSLIIGYFTKIKDCEHVLIQIMLKSENLLTSEITHFKSERMD"
BASE COUNT         2539 a          803 c         1165 g         2193 t
ORIGIN      
        1 ttatcactaa tcttacattt taaaatatta tttttactcg taatattatc ataagaattt
       61 gtttcttatt taaaactaat tagaattata aagtttattg ccatgttatt aataaaataa
      121 atccagttaa atcgagtgct agttaaagta ataagaaact tttacaatgg tttcctttat
      181 cgattgaaat aaaagttaat atggtataat atctaaagag agaatcttat caattagaat
      241 atgcatagaa acaagtggct taaaaggaga cgttatatgg aagagatagt aaagaaggaa
      301 caagcaagta tgaatgatat ttttttgtat cttaaagcta aatcaaactc attatataaa
      361 tttgtaatat tatataatga gtttatcaat aaacctaaag attatggaac tggggaactt
      421 ataaacatgg ttgaagtaca tatgctaaca gcgattgaag aaaatccagg aataagtcca
      481 actcagttag ctaaaatatg gaacagaact aaaggtgcaa tatctcaaac tatatctaaa
      541 ttggagaaaa agggttatat aactaaagaa aagaaagaag gaaatgcaaa aactatatta
      601 ctatatccaa ccacatcagg agtagagtta agtaaggcac ataaactata tgacaccata
      661 gatgttacaa gaacatttga atacttaatc aaggagtgta cattagagga gatagatagt
      721 ttttataaag taattgattt gtttattaat ttattagaag aatctccgca ggaaaataat
      781 gattctgaaa aagtgtagct gagattgaag ttgaataaag agaaatagat attatagaag
      841 tagtacttaa gtacacatta tataaaaata taataggtat aggattaaaa agtttagtgg
      901 tttaaagttt aaccactaaa cttttttaat gtctataatc tactattatt taatttacta
      961 aaaataaaaa aactcattat attaagatag aaatagaaaa ataactagaa aaatactata
     1021 atatatcagc ttaatacaga aaaaagttaa aaaatttgag aaaaataaaa atgaaaacgt
     1081 tttatattga catagagaaa aagtagtgat accatttaaa tatagtttag tagctaaact
     1141 atatttaaat tataataact attttagggg gatgttatga atttaaaaca attaagtgaa
     1201 aaatacgaag aatatgtaat tcaaatgaga agagaatttc ataagtatcc agaattatct
     1261 tttaaagaaa taagaacaac ccaaagaata agggaagaat tacaaaaaat aggggtccct
     1321 tttgtatcta ttgaaccaaa tatcgtaata gctactatac aaggcaaaaa tgaaggtaag
     1381 acaattgcaa ttagaggaga tatagatgcg cttccaatgc aagaagattc agatgttgaa
     1441 tacaaatcag aatatgatgg aataatgcat tcttgtggac atgatgctca tggagctatg
     1501 ttactaggac ttgcacatat gctaaatgat ataagaaaag atttaaaagg tagagtatta
     1561 ttagtttttc aagcagctga agaagttggt ggtggacaca aggagataat acagtacttt
     1621 aaggaaaatg gaggaccgga tagattaata gctactcatg tttggtccga tattgaagct
     1681 ggtaaaattt ctgttgaacc aggacctcgt atggctggtg ggtctggttg gagaatagac
     1741 ataacaggta gaggaggtca tggttctaga ccagatcaaa gcatagatcc tataaagcca
     1801 gcttgtgata tagttttaaa agtatcttct ataccagtta atcatataag tgtactagaa
     1861 caatgtgttg tacatgcatg tgcaatacat ggaggaacta caataggaaa tgttattcca
     1921 aacaatgcag aggtaatagg tggatataga tattttactg aagaatcagg caaaaaagtg
     1981 tttgacatta taaagcaaat gagtaatggt gttggacaag tttatggagt ggatgtgaag
     2041 gttactcata ctggaggcat aggacctgtt atcaatgatg aagaagcagt taagatggct
     2101 aaagaaatag tttctaatat agatggattg gagttagatt cttatgagcc aatatgtgca
     2161 tcagattgtt atggtgaaat attaaaagag tattctggct tttattgtta tctaggggta
     2221 ggtaacaaag aaaaaggaat aatatatgca caacaccatc ctaagtacaa tatagatgaa
     2281 gatatattaa agttaggttg cgaatttatg gctaaatatg cagttgaatt tttaaataaa
     2341 aataataact aaaataaatc taattttata aatgggggga tgaaaatgca aggtgcatta
     2401 aaggaaaata agaaaaaaag tggtggagga tttttaggat ggattgaaaa agttgggaat
     2461 aaaatgccac atcctctagc attatttaca tatattacac tgatagtagt agcattatct
     2521 gcaatagcaa gctttttagg tttttcagca acaagtcctg ctacaggaaa gttaataaaa
     2581 gttatgaact taataagtgc aaaaggttta gtactattta tgcaagagtt tgttaagaac
     2641 ttccaaaact tccctgtgct tggagtagtt ttagttatgg cagttgccac aggagtttgt
     2701 gaaaagacag gatttttttc aactgccata aaaatgagtt tatcaaaagt taaggggaat
     2761 gcggttgtat ttataatagc ttttatagga gtatttgcta atcaagctgg tgatgctgct
     2821 tttgtattag taccaactct tgcaggagca atattttatg gattaaatag aaatccatta
     2881 gctggtatat tctgtggatt tgcatcagtt ggtggtggat ttgcaacagc tgtaattcct
     2941 gggggatggg acgttacgct aacgccaata actgtatcag ctgctcaaac tattcaacct
     3001 gcatttgata tgacattatt agctagttat tatgcactat ttgtatctgc gtttatagta
     3061 gctacagtat caacaatagt aacggttaaa tttatagaac ctaaattagg taagtatact
     3121 ggtaaaccag aaggtataga tgataatcaa ggttttgagg tcacaaaaga acaagcaaaa
     3181 gcagcaaagt tagcaggttt tacagtttta gcttatgtag cgttattaat tgctttgtgt
     3241 ataccagcta atagtttttt aagaagtcca gaaggttctt taatatttgg agcaccactt
     3301 atgtcttgct tacagttttt tatagtaata ctattcttct tgccagggat tgtgtatgga
     3361 atgagggttg gtaaaatcaa gactgtaaaa gacttaaatg atatattatg tcaatcaatg
     3421 gcagcaatgg caccgtttat cgtacttgca atagttatag gtcaattctt aacgctattc
     3481 tcagtgtcta atttagcaca ggtactagct ataaaaggtg gagcattact caactcattg
     3541 ccactaccac cacaagctat aatactgcta ttcttagtac tagtagcgtt tataaatata
     3601 tttgttataa gcggaagtac aaaatggatg atatttggac cagtatttgt tccaatgtta
     3661 atgcaattaa acatacatcc agcatttact cagtttgtat atagattagg agattctgta
     3721 accaatcatt tatcaccatt aaatgcattc tttataatac ttttagcaac agtccaaaaa
     3781 tacgataaaa atgcaggtat gggaactata ttctcagcta tgatacctta cactataggt
     3841 tactttgtag tacttgcagt tttagtagta gtttggatga caataggtat accagtagga
     3901 ataggtggac aagtttggtt ataaaacata tttaataatt ttgggaggaa aaaaaatgga
     3961 aacaactgaa ataagataca attttgatga agtaatagat agaagtggaa caaactgtct
     4021 taaatatgat cttaagagtc aatttatgcc agaatctcca gaagatgcac taccactatg
     4081 ggtagcagat atggattttg catgtgcccc tgagataatt aatgcaatgc atgaaagaat
     4141 agacagaaaa atatttggat atagctctca acaaactgat gattattatg aagctgtatg
     4201 tggatggttt aagagaagat ttgattggaa aatagaaaaa gagaatatat tctttagccc
     4261 aggggttgtg cctgcgttag gatttttcac acaaatatta acacaaaagg gtgatggtat
     4321 cataatagaa aagcctgtat actatccttt tgaagataaa ataactaaca atgaaagaaa
     4381 agtagttaat agtcctttaa agtttgaaga tggtcattat tctatggatt atgatggatt
     4441 tgaagaatta gctaaagatg aaaataataa ggtgtttata ttatgtagtc ctcataatcc
     4501 agttggtaga gtatggaaaa aagaagagct tagaaaaata gtagacatat gtaagaaata
     4561 tgatttgtgg ataatatctg atgaaataca ttgtgatatt attcgtaaag gtgaaaagca
     4621 tataccatta gaagtagcat gtcctgatta taaagataga ataataactt gtacagctcc
     4681 aagtaagagt tttaacttag ctggtatgca attatcaaat atagtaatca ataataagga
     4741 attacaagaa aaatggatgc ttgaaacaga ttctaaatta gctatattcc tacctaatcc
     4801 attcgcaata gttgctacta aagttgctta taatgattgt gaagattgga tgaatcaagt
     4861 aaatgagtat atagatggta atattaaata tgtagaagat tttgttaatg agtatatgcc
     4921 taaagtaaag ataataaaat ctcaaggaac ttacttagtt tggttagact ttagagggta
     4981 tggattagat gcaaaacagc ttgaatatgt aatgcttaac aaggcgaagg tattgctaga
     5041 tgaaggatac atattcggag aagaaggagc aggatttgaa agaataaatg ttgcttcacc
     5101 tagaacaatt atagaagagt gtatgaatag aataaaatgt gcatttgaag gattataata
     5161 gtaatatcta aataatatat ttgtgtattt taaaaaaaga ctatgctaaa aaaatatttc
     5221 aaagcatagt cttttaaagt tttatgatga gtttaaaaaa tttcaaaacg ttactattca
     5281 cttatatgtt tatattagaa ataattccac aatatactca ttttctaaag ttgcactttt
     5341 atacaccttg cttcaccaat atcatgtgta accaaaatag tagacttatt ctcattctta
     5401 ataatactat aaacatcatc acaaactaat aatctagtct gataatcaag agctgaaaaa
     5461 ggttcatcta aaagtagaat atctggattt acagaaagtg ttctaataag cgcaactctt
     5521 tgtctcatac ctccagataa ttcttttgga tacatacttc taaaatccca taatccataa
     5581 gtctttaaaa ggctttcaac tctatctaaa gattttttat cttttttgcc ttgaatttcc
     5641 aatccaatag ttatattatc cattatattt ctccattcaa gcaaattatc tttttgaaac
     5701 atatatccaa tatttccagt aatctttata tcaccactag ttggttttaa aagattagta
     5761 agaatattta atattgtaga tttaccactt ccagaaggac caagcaaagt taatatttct
     5821 ccttctttca agttaaaatt gacatccttt aatacttcaa gctcgccttc cttagtgtag
     5881 aagttcatat ttatattttt aacttctact atgttgtcat tcattatgcc accccctata
     5941 acttttagct cgtatatatt atgttattaa caatatgacc tatttgtacc atttttcata
     6001 aatataatat aaatattttg tttatttacg tattttctta gtaacttgta cgtataaatt
     6061 atagataaat aaattataag gtaggggata aatttgagta acataataac gaatttaata
     6121 gagtcaatat ttactaatcc aataactata ttgtttttac ttgcaataac tgtgtattct
     6181 gtttttaaaa taatagaaaa taacagagta tattcatttg taagttcaaa attagacgaa
     6241 atcaatagag actataagac aagtgagttt tataaaaagg taagggatga ctactataca
     6301 tatagtaaag aaaatcctta tgcagacgta aatataactt catttataga ggaagttgta
     6361 tctgatttaa agcataataa tttgccattg ttagaaaaaa ttagaagtat aaaaaattca
     6421 tcttcaataa gtatattact tggggtttta ggtacgtttg ttggtctttc tacaatgctt
     6481 ttatgtgttg atactaaaga cattataaat tcacttcctt caactattag tagtatgcaa
     6541 actgcattta caactagtat atttggagtt gtattttctc taattatagg ttattttact
     6601 aagataaaag attgtgaaca tgttttgata caaataatgt taaaatctga aaatttacta
     6661 acatctgaaa taactcattt taagtcagaa agaatggatt
//
LOCUS       DAEPKC010000146         6677 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.148, whole genome shotgun sequence.
ACCESSION   DAEPKC010000146 DAEPKC010000000
VERSION     DAEPKC010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6677)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6677)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6677
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.148"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(<1..792)
                     /locus_tag="KR294_003480"
     CDS             complement(<1..792)
                     /locus_tag="KR294_003480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBH0241527.1"
                     /translation="MYLERPELYKQSEINFWDDEYISKQLLKAHLDTNFEGASRNFNF
                     IEDSVNWIVTVANPANYPKLLDLGCGPGLYAEKFAQKGYKVTGIDFSKRSINYAQNRN
                     KETNLNINYLFQSYLNMNYNEEFDLATLIYCDYGALSTENRRLLMEKIYDSLKPGGKL
                     ILDVFTINKYNNFEEIKYWEINEDGGFWSNEKYMCLQDNCKYNDYNTLEQTLVITEKD
                     ENVFYVWNHYFSKESFLLEVENIGFKSVEFFSNVKGEAYSDDSMTM"
     gene            complement(1162..2064)
                     /locus_tag="KR294_003481"
     CDS             complement(1162..2064)
                     /locus_tag="KR294_003481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBH0241528.1"
                     /translation="MYNKIKYIPINCEIACNKLKRSMPYKWDLNIYRGCEHGCKYCYA
                     IYSHKYINSNNYFEEIYVKTNIVEKLERQLKSSKWKKEVINIGGVTDSYQPIEADYKI
                     MPEILNLLIKYKTPAIISTKSDLILRDYDLIDKLSRITYINVASTITTVNEDTQRLIE
                     PNGVDSMRRFKMLKEFRKTNASVGLHIMPIIPYITDDFDNINSLFRHAKECNVHYVLP
                     GTLYLRGITRGVFFDFVKKEFPELFDKLSILYSAGSLNREYKNQLYKMVNELRYKYSL
                     SSSYSKIMKEKLKNSGDVQISFFD"
     gene            complement(2114..2575)
                     /locus_tag="KR294_003482"
     CDS             complement(2114..2575)
                     /locus_tag="KR294_003482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine dimer DNA glycosylase/endonuclease V"
                     /protein_id="HBH0241529.1"
                     /translation="MRLWHKDLIDVLPKNQLVSQWRELLAIKGSIDKKGTPNHLLVNK
                     VLNYSIDEFKFYTKIVHDEMLKRNYKPNELKYTSILKWKNRNFANDISNEHSLNLENL
                     YDDWHNKMYLKQCLYNLEEKATCGGIPINEWNILLCKYSKDYELWSGNIMF"
     gene            complement(2627..3082)
                     /gene="def"
                     /locus_tag="KR294_003483"
     CDS             complement(2627..3082)
                     /gene="def"
                     /locus_tag="KR294_003483"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HBH0241530.1"
                     /translation="MAIRKIRTFDDEILRKKSKYVENVDNKIREILNDMAETMYNTPN
                     GGGLAACQVGVLKRLVVIDLGEGLIKLVNPEIIEQEGEQIVVEGCLSFPEVWGKLKRP
                     KKVTVQALNEYGEKIEIKGSGFMAKCLCHEIDHLNGIVFTDKIIEHVKL"
     gene            complement(3054..3317)
                     /locus_tag="KR294_003484"
     CDS             complement(3054..3317)
                     /locus_tag="KR294_003484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0241531.1"
                     /translation="MKNKIKILREKLGLTQEQLGRLVGTSRQAINAIETGKNEPSIWL
                     AYDISRIFNEPIESVFLFEESERKSRAQISRGEYYGYKKDKNI"
     gene            complement(3414..4130)
                     /locus_tag="KR294_003485"
     CDS             complement(3414..4130)
                     /locus_tag="KR294_003485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0241532.1"
                     /translation="MIKIINAFKQEFEQIKRDAMLFIVCVSPILCGVFIKFGIPLIQN
                     ISLNKFYYQLNLEPYFLMFDLLLAFITPFMFFFASTMVILGEIDDSISRYLIVTPLGK
                     TGYLISRFGIPGILAFIITMILLIFFSLTKISLLLNLSISLLVLLQGVIISILVISLS
                     SNKLEGMVITKFSGVFMMGILAPFFILNKAQYILFFLPTFWISKAFKEDNYVYMFISI
                     VISLIWILLLFKKFSKKIVK"
     gene            complement(4127..4810)
                     /locus_tag="KR294_003486"
     CDS             complement(4127..4810)
                     /locus_tag="KR294_003486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0241533.1"
                     /translation="MRLKNLILGDIKFQFKYGFYFLYLFLSIIYICIINVFPTFMREK
                     IAIIMIYSDPAAMGLFFMGAIVLLEKSQRVLNSLAVSPVKVSEYILSKVISLGVISSI
                     VAMFIAITLNLDNIIISTIGTFFSSIIFSLLGLIIASKASSLNQFIVLSIPIEIICFI
                     PPILNVLLDTKSYANLYPFNICISLISGDKNFIMINILILISIIIIIYFITYYFICSS
                     WKKVGGVKL"
     gene            complement(4807..5652)
                     /locus_tag="KR294_003487"
     CDS             complement(4807..5652)
                     /locus_tag="KR294_003487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0241534.1"
                     /translation="MIKVDDLSFSYTDRDFLQNINFEVGKGEILGFLGPSGAGKSTLQ
                     KILIGMITNYGGSVIVNGVESKRHSNKFYENIGVDFEFPSLYEKLTAIENLKYFGSLY
                     SKKLLSIDELLKSVGLENESNKRVSEYSKGMKSRLNFIKALLHNPDILFLDEPTSGLD
                     PSNSKVMKDIILSEKSKGKTIILTTHNMLDATELCDRVAFIVNGKISALDTPHNLIMS
                     KGAIKVRYTYFDNGEKTSECFLNNTANDKNLNMLIEKNKLLSIHSSEPTLNDIFIEIT
                     GRNLQ"
     gene            complement(5766..6356)
                     /locus_tag="KR294_003488"
     CDS             complement(5766..6356)
                     /locus_tag="KR294_003488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH0241535.1"
                     /translation="MPKSYSDKEREYIIKRLKEEARLCMEQYGIRKTTVDELVKRVKI
                     PKGTFYLFFQSKELLFFEVLRDIHDSIQKEILYEINRVDESITCEQLTDIFMKFYRMV
                     DSTSILNLMINGEFEILVRKLPDSIIEEYFRHDDFEIGEIISCIPNAKNKDIESFSGA
                     FRAVFLTMLYKREVGSNCFEDALRLMINGLVIQLME"
BASE COUNT         2360 a         1060 c          622 g         2635 t
ORIGIN      
        1 catagtcata ctatcgtcag aatatgcttc acccttaaca ttactaaaaa actcaacaga
       61 cttaaatcca atattttcaa cttctaataa gaaactttct tttgaaaaat agtgattcca
      121 aacataaaat acattttcat ctttttcggt tattacaaga gtttgttcta atgtattata
      181 atcattgtat ttacaattat cttgtagaca catatatttt tcattactcc aaaatcctcc
      241 atcttcattt atttcccaat atttaatttc ctcaaaatta ttgtatttat ttattgtaaa
      301 tacatctaat attaattttc ctccaggttt taaactatca taaatttttt ccattaataa
      361 ccttctattt tcagttgaca aagctccata atcacaataa attaaagtag ccaaatcaaa
      421 ttcctcatta tagttcatat ttaaataact ttggaacaag taatttatgt ttaaattagt
      481 ctccttattt ctattttgtg catagttaat agaacgtttt gagaaatcaa ttccagttac
      541 cttataacct ttttgtgcaa atttctctgc atataaacct ggaccacaac ctaaatcaag
      601 taatttagga taattagctg gatttgcaac tgtaactatc caatttacag aatcctcgat
      661 aaagttaaaa tttctacttg ctccttcaaa attagtgtct aagtgtgctt ttaataattg
      721 ctttgaaata tactcatcat cccaaaaatt aatttcactt tgtttataaa gctctggtct
      781 ttctaaatac atacataatt tgtttaacaa aacataccac tccttaaaat ttatttttaa
      841 aataaaaaaa ccacagagtt tactctgtgg tttaacttca aaaagatgag tttaaataag
      901 agtaaaatag aaccaaatat ttttaagcac aacaataaaa ctatagcttt actttgtttg
      961 cttattaaat ttgattttat tcactctttt ccagcaatac ttatatcaac gattttatga
     1021 tatcaaatat caccgaacaa catcatcctt tcatattttt attttatgaa ttaattatat
     1081 atttaaattt tatatttgtc aataaatttt aattttaata aattttaatc atcatagtaa
     1141 aaaaaatttt tttatataaa actaatcaaa aaaagatatc tgtacatctc ctgagttttt
     1201 taacttttcc ttcattattt tagagtaact gcttgataga gaatacttat atctaagttc
     1261 attaaccatt ttatacaatt gatttttata ctccctatta agtgaacctg cactatatag
     1321 tattgataat ttatcaaata attcaggaaa ctctttttta acaaagtcaa aaaaaacacc
     1381 tctagttata ccccttaagt ataaagtccc aggtaaaaca taatgtacat tacattcttt
     1441 tgcatgtcta aatagcgaat ttatattatc aaaatcatct gtaatatatg gtataattgg
     1501 cataatatgt agaccaactg atgcgttagt ttttctaaat tcttttaaca ttttaaatcg
     1561 tctcattgaa tccacaccat ttggctcaat aagcctttgt gtatcttcat ttactgtggt
     1621 aattgtagat gctacattga tatatgtaat cctagatagc ttatcaatta aatcgtaatc
     1681 tcttaaaatt aaatctgact ttgtagaaat aatagctggt gtcttgtatt ttattagcag
     1741 gtttaatatt tctggcataa ttttatagtc agcttctatt ggttgataac tatctgtaac
     1801 tcctcctata ttgattactt ctttcttcca tttactgctt ttaagttgtc tctcaagttt
     1861 ttctactata tttgttttta cataaatctc ttcaaaataa ttattggagt tgatgtactt
     1921 atgagagtaa atagcataac aatatttaca tccatgctca catccacgat aaatatttaa
     1981 atcccattta tatggcatac tcctttttaa tttattacaa gctatttcac aatttattgg
     2041 aatatatttt attttattat acaaataatc acctctttat atacaataat actataatgt
     2101 taatctatag taattaaaac atgatatttc cagaccacaa ttcataatct ttactatatt
     2161 tacaaagtaa tatattccat tcatttattg gtattcctcc acatgttgct ttttcttcta
     2221 aattatataa gcattgcttt aaatacattt tattatgcca atcatcatat aaattttcta
     2281 aatttaaact atgttcatta gatatatcat ttgcaaaatt tctatttttc cattttaata
     2341 tacttgtata tttaagttca ttaggtttat aatttctttt taacatttca tcatgtacaa
     2401 tttttgtata aaatttaaat tcatctatac tataattcaa tactttattc actaatagat
     2461 ggtttggagt acctttttta tctatagaac cttttatagc aagtagctct ctccattgac
     2521 ttactaattg atttttaggt aatacatcaa ttaaatcctt atgccataat ctcataattt
     2581 aactccttac tataaaatat tttataaatt caataaccaa tctatcttac aattttacat
     2641 gttcaataat tttatctgta aaaactatac catttaaatg gtctatctca tgacaaagac
     2701 attttgccat aaaacctgaa cctttaattt ctattttctc accgtattcg tttagagctt
     2761 gcactgtaac tttttttggt ctttttaatt taccccatac ttcaggaaaa cttaaacatc
     2821 cttcaacaac aatttgttcc ccttcttgtt caataatttc aggattaaca agcttaataa
     2881 gtccttctcc taaatctata acaactaatc gctttaatac tcctacttgg catgcagcta
     2941 atcctcctcc atttggagta ttgtacatgg tctctgccat gtcatttaat atttctctta
     3001 tcttattatc tacgttttct acatacttac tcttttttct taaaatttca tcatcaaatg
     3061 ttcttatctt tcttatagcc ataatattct cccctactta tctgtgctct tgattttctt
     3121 tcactttctt caaataaaaa tacactttca attggttcat taaaaattct tgaaatatca
     3181 tatgccaacc atattgaagg ttcattttta ccagtttcta tagcatttat agcctgtcta
     3241 gatgttccaa ctaatctccc tagttgttct tgtgtcaatc ctaatttttc tcttaatatc
     3301 tttattttat ttttcatatt tgctccattc atgtaaggtt aactttacat cttaaatgta
     3361 acatttttca acattactgt caagtcaacc ttacatttat atattaaatt ttcttattta
     3421 actatttttt tactaaactt tttaaataat aataaaatcc atattaatga tataacaatt
     3481 gaaataaaca tatagacata attatcttcc ttaaatgcct tcgatatcca aaaagttggt
     3541 aagaagaaca gaatatattg tgctttattt aaaataaaaa atggtgctaa aatacccatc
     3601 ataaaaacac ctgagaattt cgtaattacc attccttcta gtttatttga tgataaagaa
     3661 atcactaata ttgatataat aactccttgt aataaaacta ataaagaaat tgataagttt
     3721 aacaagagag aaattttagt tagagaaaaa aagataagta gaatcatagt aataataaat
     3781 gctaagatac ctggtattcc aaatcgtgaa ataagataac cagttttacc aagcggagtt
     3841 actattaaat atcttgaaat gctgtcatca atttctccca atatgaccat tgtagaagca
     3901 aaaaagaaca taaaaggtgt aataaaagct aaaagtaaat caaacatcaa gaaatacggc
     3961 tctaaattta attgataata aaacttgtta agtgatatat tctgtattaa tggtattcca
     4021 aattttataa atactccaca taatattgga gaaacacata ctataaaaag catagcatct
     4081 ctcttaattt gttcaaactc ttgtttaaac gcatttataa tctttatcat agttttactc
     4141 cacctacctt tttccaactg ctacaaataa aataataagt tataaaataa attattatta
     4201 taattgatat taaaattaaa atattaatca ttataaaatt tttatctcca ctaataagag
     4261 aaatacatat attaaaaggg tacaaatttg catatgattt tgtgtcaaga agtacattca
     4321 gtattggtgg aataaagcat ataatctcaa taggaatact taaaacaata aactgattca
     4381 aactagatgc tttacttgca attatcaatc caagcaaaga aaatataata gaagaaaaaa
     4441 aggtacctat agttgatatt ataatattat ctaaatttaa tgtaatagca ataaacatag
     4501 ctacaatact agatattact cctaatgaaa ttacctttga taaaatatac tcagatactt
     4561 ttactggaga tacagctaag gaatttaaaa ccctttgact tttctcaaga agtacaatag
     4621 ctcccataaa aaacaatccc attgctgctg ggtcagaata aatcataatt atagctattt
     4681 tttctctcat aaaagttgga aatacattga taatacaaat atatataata cttaaaaaaa
     4741 gatataaaaa ataaaaacca tacttaaatt gaaactttat atctcctaaa ataagatttt
     4801 ttagcctcat tgtaaattcc tccctgttat ctcaataaaa atatcattta atgttggttc
     4861 actactatgt attgataaaa gtttattttt ctcaataagc atattcaaat ttttatcatt
     4921 agcagtattg ttcagaaaac attcagaagt tttttctcca ttatcaaagt aagtatatct
     4981 aactttaata gctccttttg acataataag attatgtggt gtatctaaag cagatatttt
     5041 accatttaca atgaacgcta ctctgtcaca aagctctgtt gcatctaaca tgttatgagt
     5101 tgttaaaata atagtcttac ctttcgattt ttctgataaa attatatctt tcataacctt
     5161 gctatttgat gggtcaagac cacttgttgg ttcatctaaa aataaaatat ctggattatg
     5221 taataaagct tttataaaat ttaatcgaga tttcatacct tttgaatact cagataccct
     5281 tttatttgat tcattttcta gtcctactga ttttaataac tcatcaatag atagtagttt
     5341 tttagaatat agagacccaa aatattttaa attttctatt gcagtcaact tttcatataa
     5401 actaggaaat tcaaaatcaa ctcctatatt ttcataaaat ttatttgagt gtcttttact
     5461 ctctactcca tttacaatga cacttcctcc ataattagtt atcattccaa ttagaatctt
     5521 ttgtaatgta gattttcctg cacctgatgg tcctaaaaat cctagtattt ccccttttcc
     5581 tacttcaaag ttaatatttt gtaaaaaatc tctatctgta taactaaatg ataaatcatc
     5641 aactttaatc attcaatatc accctttcaa atttttgact attttgacta tatggtcaat
     5701 aaaatataat ttttttgttt gttaataatt tttaataaaa gttattagca aacaaaattt
     5761 aaattctatt ccataagttg tataactaat ccgtttatca ttaatcttaa agcatcttca
     5821 aaacaattac ttccaacctc gcgcttatat agcatggtaa gaaaaactgc tctaaatgct
     5881 ccactaaagc tttctatgtc tttatttttt gcatttggta tgcaagatat aatctctcca
     5941 atttcaaagt catcatgtct aaagtattct tcaattatag aatctggtaa ctttctcacc
     6001 aatatctcaa attctccatt tatcatgaga tttaaaattg aagtactatc aaccatccta
     6061 tagaatttca taaatatatc tgtcaattgt tcacatgtaa tactttcatc tactctattt
     6121 atctcatata agatttcttt ttgtatagag tcatgtatat ctcttaatac ctcaaaaaag
     6181 agtaattctt ttgattgaaa aaatagataa aaagttcctt ttggtatttt tacccgtttt
     6241 acaagctcat caacagtagt ttttctaata ccatattgct ccatacacaa tcttgcttct
     6301 tctttaagtc tttttattat atactctctt tctttatcag aatatgattt aggcatcttt
     6361 tccctccagt ttgactaaaa taatttatat agtcaatata atactttttc tatctaatgt
     6421 caatagtatt attagtatat ttaaaaataa gcttaaaaac tttcgaaaat tctgaatttt
     6481 atatagcatt ttttattatc tagtgttata attaagatat aaataatata ttattctaat
     6541 tttcatatct atttgcttat tttttaactt agtttctaat agaagtaatc atatttatct
     6601 ttttaaaagt ttcaacttta ataaaaaata aaggagttga ttttatggct actactacaa
     6661 aaaaccgttt ttacgat
//
LOCUS       DAEPKC010000147         6623 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.149, whole genome shotgun sequence.
ACCESSION   DAEPKC010000147 DAEPKC010000000
VERSION     DAEPKC010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6623)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6623)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6623
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.149"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(<1..172)
                     /locus_tag="KR294_003489"
     CDS             complement(<1..172)
                     /locus_tag="KR294_003489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH0241536.1"
                     /translation="MIAVKKAYKFRMYPNKKQQELINKTFGCCRFVYNKYLAKRIDVY
                     KNDKETFTYKQCS"
     gene            complement(820..1227)
                     /locus_tag="KR294_003490"
     CDS             complement(820..1227)
                     /locus_tag="KR294_003490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241537.1"
                     /translation="MSKVAKATFYLMIVTIISKILGMGRELVLSSIYGTGLYTESYLT
                     AMNIPNIIFAAIGTAIVTTFIPMYQDISSKQGEKQALKFLNNVLNIIVGICIVVAILG
                     VIFSKQLVSIFAIGFEGERFLLTVKFTKILIKK"
     gene            complement(1701..2585)
                     /locus_tag="KR294_003491"
     CDS             complement(1701..2585)
                     /locus_tag="KR294_003491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBH0241538.1"
                     /translation="MDTKKENNYENYICVGSSNVSNAMKMYLKEIEEYKMLSAGEEVE
                     LAKEIINSSSVAKEKFINSNYRLVVSIAKRYKRDSIDMLDLIQAGNIGLIKAVEKYDY
                     KKGYKFSTYATWWIKQSITRYIDDCENTIRIPIHLHQRINFVKKKKQELLNVLLREPT
                     IDEIADACGLEVDKVLELLRRDKNVVSLDTPLKEDEDSSLVEFIPSDADFKDVVIHEV
                     EQHNLKEKIEELLTGLGEQEQQVLRMRFGIDDDDPKTLEQIGKVFGVTRERIRQIEAK
                     AIRKLRHPSKLKQLKHFY"
     gene            complement(2876..3352)
                     /locus_tag="KR294_003492"
     CDS             complement(2876..3352)
                     /locus_tag="KR294_003492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction enzyme HsdR N-terminal
                     domain-containing protein"
                     /protein_id="HBH0241539.1"
                     /translation="MSKELVKDRVIKYLIEDLLVPQDMIDTNVELAEFEEGAEGILDI
                     VVNVKDEEDYYAPVMIVQCLDEDVELEGEVLQKQIEFLEEVDNITMSGRLVLTNGDAM
                     MYADWRGEEYDTEAALPTYDIMVKEFHEMEQQVKDLEEHHHHDENCGCGCNHHHEN"
     gene            3618..4793
                     /locus_tag="KR294_003493"
     CDS             3618..4793
                     /locus_tag="KR294_003493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HBH0241540.1"
                     /translation="MKFKKQISSIVVSTMLVLGSMNLSYADGTNVVTLGANLSESQKQ
                     QMLNYFGVKKDQVLVLDVTNAEERQYLQGVATEGQLGKVTISCSYVEPTKKGNGINVK
                     TANLTWVTSSMIASTLTTAGLEDANVIAAAPYPVSGTGALTGIMKAFEDASGKKLDET
                     KKEIASEELVVTGDLGDDIGQEKATGVMNDIKTEIVKNGTKDTNQIANTINNVVNNYN
                     ITITPEQKEQIKGVMKKIADQNYDYNSMKNTLDNVSDNVNEQLKKLGESVKGSGILDT
                     IGGWFSGIGDWFSGLFSGGDKKDLGILNNTNDESLGSDAVINSTEGVQINPQNNTNSN
                     NDSDTNSSKNDTSSNNENNDSSQTNENNTTNNSENQSNNNDSVGFFEKIKNWLSGLF"
     gene            complement(4874..5677)
                     /gene="proC"
                     /locus_tag="KR294_003494"
     CDS             complement(4874..5677)
                     /gene="proC"
                     /locus_tag="KR294_003494"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HBH0241541.1"
                     /translation="MKKIGFIGAGNMASAMIGGIVNSKLVEPNMVIASAYSQGTLDRI
                     DANFGINTTKDSKEVTRTSDIVIVAVKPDIYDDILEEIKDFIDDNKIIVTIAAGKSIK
                     DIESIIGEDKKIVRTMPNTPALVNEAMSSLSINKNINKEDLEAVTEVFNSFGNTEVVP
                     EYLIEAVIGASGSAPAYVFLFIEAIADAAVIAGMPRPQAYKFASQAVMGSAKMVLETG
                     KHPGELKDMVCSPGGTTIEAVKVLEEEGFRASVIKAICACIEKSKKMSE"
     gene            complement(5717..6301)
                     /locus_tag="KR294_003495"
     CDS             complement(5717..6301)
                     /locus_tag="KR294_003495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0241542.1"
                     /translation="MNKDIGAKIKQLRTQKQMTLKDMSEKTNLSIGFLSQLERGLTSV
                     ATDSLGKIASVLDVELTYFFMKPKEHKRAVLRSYEKEVFDVENSTFIHYHLSSSLKEK
                     TMLPRLIEILPSKSSEEICCYVHEGEEFVYVLEGTLTVFLGDEQIEMYPGDTIHYNSE
                     KNNHNWVNYTNKVVKILVVSIPNPFEKSDAVKEA"
BASE COUNT         2180 a         1129 c          741 g         2573 t
ORIGIN      
        1 aactacactg tttataagta aaagtttctt tatcgttttt ataaacatct attcttttag
       61 caagatactt attatataca aatctacaac atccaaaagt tttgttaatt aactcttgtt
      121 gttttttatt tggatacatt ctaaacttat aagctttttt cactgctatc acctcacttt
      181 aattgttttt tgatacactt tttaatgatt ttatcacatt ttatcacatt taatatatta
      241 tataatgctg tggtaaacaa tttattaatc acctataata atgttaacaa atgtaattat
      301 ttaaaacaat tatttagaag gttttatatt taattttaaa taacatattt aagaaccgta
      361 agtcttaact tttatcattt tgaggttgtc gttcacataa gttcgctact acctatgcag
      421 ttctcttatg aacttcttac attttcatgt aagcacagac tatatcttat ccttcagcat
      481 tatccgttaa ggtctaccca cttccactac caatagcttg tagtgtactt ccctcaagag
      541 gaatagtcgt tgaagtttct cctgttcgga gtttacctgc tgattgccca ttttaaagta
      601 cttaggattt aaccttatac catctaacca attttttcta ctttcgtaac tttcacactt
      661 aggtttattt catccttatg ttttagtttg attagcttta ggggtttcca gcaattcaag
      721 tagtattgga taggttctat cctatctcta catataggtt tccctatatg ctgactattt
      781 tagctactaa ctcatgacta aagtcacgag tgtgtgtagc tattttttaa tcaatatttt
      841 agtaaatttt acggtaagta aaaacctctc tccttcaaat cctatagcaa atatacttac
      901 aagttgcttt gagaaaataa ctcctaatat agctacaact atgcatatac caactattat
      961 atttaaaaca ttgtttaaaa actttagtgc ttgcttttca ccttgtttac tacttatatc
     1021 ttgatacatt ggaataaaag tagtaactat agcagtacct attgctgcaa atataatatt
     1081 tggtatattc atagctgtta aataactctc tgtatataag cctgtaccat aaattgatga
     1141 taatactaat tctctaccca ttccaagaat cttagagatt atagtaacta tcatcaaata
     1201 aaaagttgct ttagctacct tgctcatttt atcactccac ttctaacata cctcttttta
     1261 atcaagtaaa atttagctca ttagatataa ttctatcaac taatttgcct tgcttagccc
     1321 tatcaaaata taattaacac ctatttctta atatatcaca aactacatta ttcttcatat
     1381 ttttttattt ctccaataag ttttacattt ttcctatata aattgtatag cttcaattat
     1441 attcaaagaa atggagttgc tacccgataa ctttaaaagt aaaaaacaga ttttattatc
     1501 tttttaaact atattctaac atattttgtc catattgaga aattttacta aactattatg
     1561 tactttatta aataaataaa ataacagcac acctataaaa tacaagtgtg ctgttcataa
     1621 acagatttta taaaaaaata attcctaagt agagattaac atgctttctc atactctcat
     1681 atataatgtg tctaaaaata ttaataaaaa tgttttaatt gttttaactt acttggatgt
     1741 cttaattttc ttattgcttt agcttctatc tgtcttattc gttctctggt aactccaaat
     1801 acctttccaa tctgttctag tgttttaggg tcatcatcat caattccaaa tctcattctt
     1861 aaaacttgct gttcttgctc tccaagacct gtaagtagtt cttctatctt ttcttttaaa
     1921 ttatgctgtt caacttcgtg tattacaaca tctttaaaat cagcatctga tggtataaat
     1981 tcaactaaac tactatcctc atcttctttt aatggagtat ccaaagatac aacattttta
     2041 tctcttctta ataattccaa cactttgtca acttctaagc cacatgcatc tgcaatctca
     2101 tctatagttg gctctcttaa taatacattt aaaagttctt gtttcttttt ctttacaaaa
     2161 tttattctct gatgaagatg tataggtatc ctaatagtat tttcgcaatc gtcgatatat
     2221 cttgttatac tttgttttat ccaccaagtt gcataagtgc taaatttgta tcctttttta
     2281 taatcgtact tttctacagc ttttataagt cctatatttc ctgcttgaat taaatccaac
     2341 atatcaatac tatctctttt atatctcttt gctatgctca ctaccaacct ataatttgaa
     2401 tttataaatt tttcttttgc tactgaagat gagttgatta tttccttagc cagctctacc
     2461 tcttctcctg ctgacaacat tttgtattcc tctatttcct ttaaatacat tttcatcgca
     2521 ttcgatacat ttgatgaacc cacacaaata taattttcat aattattttc ttttttagta
     2581 tccataatca aaccccttct attcatagaa tttgctaaaa caaaaataaa taatttaaac
     2641 ctacataatc tacaattaca taatatccca ttctttaaat gaattgtttt gtatattatg
     2701 tatacaaatt tataaaaact atacctataa tattattcta cttctaacag caatatcctc
     2761 cttatatata taatttattt tattatatgt tgttatattc ttagtttttt gaatgatata
     2821 tgtctaaaaa aagactgttt actaaacagt ctttttttat atatatgctc aatatttaat
     2881 tttcatgatg atgattacat ccacatccac aattttcatc atggtgatga tgttcttcta
     2941 aatcttttac ctgttgttcc atttcatgaa actcttttac cattatatca taagttggaa
     3001 gagctgcctc agtatcgtat tcttcccctc tccaatcagc gtacatcata gcatctccat
     3061 tagttaaaac caatctacct gacatagtta tattatccac ttcttctaaa aattctattt
     3121 gtttttgtaa aacttctcct tctaactcca catcttcatc taaacattgc actatcatta
     3181 caggtgcata ataatcttct tcatctttaa catttacaac aatatctaaa attccttctg
     3241 caccttcttc aaattctgcc aactcaacat ttgtatcaat catatcttga ggtactaata
     3301 aatcttctat taaatatttt attactctat cttttactaa ttcttttgac atttattttt
     3361 ctccttccga ttctataaca ttatcataat catttctata ttatagtata ctacattaat
     3421 tgttttttca atctcttaca aaaattattt tttattatct tccttatatt ccctttttta
     3481 ttacaaagtt gtaatcgcat tgatttaaaa aatagtttat atttagtata atagaaatgt
     3541 agcacatatt tttattcaat atattaataa aaaaatatat tgaaaatgta atgtatgtta
     3601 aatctaggag gaatattatg aagtttaaaa aacaaattag ttctattgtt gtgtctacta
     3661 tgcttgtact tgggagtatg aacctttctt atgcagacgg tacaaatgta gttacacttg
     3721 gagctaactt atcagagtct caaaagcagc aaatgcttaa ttactttgga gtaaaaaaag
     3781 accaagtctt agttttagat gtaacaaatg cagaagaaag acagtattta caaggtgttg
     3841 caacagaggg tcaacttgga aaagttacta tctcttgctc atacgttgaa cctactaaaa
     3901 aaggaaatgg aattaatgtt aaaacagcaa acttaacttg ggtaactagt tcaatgattg
     3961 cttcaaccct tacaacagct ggtcttgaag atgcaaatgt tattgctgct gctccatatc
     4021 ctgtaagtgg tactggagca ttgacaggaa tcatgaaagc atttgaggat gcttcaggaa
     4081 agaaacttga tgaaactaag aaagaaattg cttctgaaga attggtagtt acaggtgact
     4141 taggagatga tatagggcaa gaaaaagcaa caggtgtaat gaatgatata aaaacagaaa
     4201 ttgtaaaaaa tggtacaaaa gataccaatc aaatagcaaa tacaataaat aatgttgtaa
     4261 ataattacaa tattactatt acaccagaac aaaaagaaca aattaaaggt gtaatgaaaa
     4321 aaatagctga ccaaaattac gattacaata gcatgaaaaa tacactagat aatgtatcag
     4381 ataatgtaaa tgaacaatta aagaaattag gtgaaagtgt taagggttct ggtatactag
     4441 atactattgg tggatggttt agtggaatag gagactggtt ctctggttta ttctcaggcg
     4501 gagataaaaa agatttggga atcttaaata atactaatga tgagtctctt ggctctgatg
     4561 ctgtaataaa ttctacagaa ggtgttcaaa taaatccaca aaataatact aattctaaca
     4621 atgatagtga tacaaatagc tcaaaaaatg atacttcaag taataatgaa aataacgata
     4681 gttctcaaac aaatgaaaac aacacaacaa ataattcaga aaatcaatca aataataatg
     4741 actcagttgg tttctttgaa aaaataaaaa attggctttc aggcttattt tagaaattaa
     4801 acaaataaaa agaattgcct aaaatggaaa ttttctataa aaggcaattc tctttattta
     4861 caataaattt ttattactca ctcatttttt tagatttttc tatacatgca catattgctt
     4921 ttatcacaga agctctaaaa ccttcttctt caagtacttt aactgcttct atagtagttc
     4981 caccaggtga acataccata tcttttaatt caccaggatg ttttcctgtc tcaagtacca
     5041 tttttgcaga acccataaca gcctgtgatg caaacttata tgcttgtggt cttggcattc
     5101 ctgcaattac tgctgcatct gctatagctt ctataaataa aaatacatat gctggtgcag
     5161 aaccacttgc accaattaca gcttctataa gatactctgg tactacctca gtatttccaa
     5221 aagaattaaa tacttctgta actgcttcta agtcttcttt gtttatattt ttatttatag
     5281 aaagagaaga catggcttca tttacaagag ctggagtatt tggcatagtt ctaactattt
     5341 ttttatcttc tcctataata gactctatat cttttataga ttttcctgct gctattgtaa
     5401 ctataatttt attgtcatct ataaagtctt ttatctcttc caaaatatca tcatatatat
     5461 ctggtttaac agctacaatt actatatcag aggttctagt tacttccttc gagtcttttg
     5521 tagtatttat tccaaaattt gcatctattc tatcaagagt tccttgacta tatgctgatg
     5581 ctataaccat attaggttca actaattttg aatttactat tccccctatc atagcgcttg
     5641 ccatatttcc tgcacctatg aatccaattt ttttcacttt agtacctcct tattgactaa
     5701 tagtaatcgt taaaatttaa gcttctttaa ctgcatcaga cttttcaaat ggatttggta
     5761 tacttactac caaaattttc actaccttat tagtatagtt gacccaatta tgattgttct
     5821 tttcactatt atagtgtatt gtgtctcctg gatacatttc tatttgttca tctcccaaaa
     5881 acactgtaag agtaccctct aatacataca caaattcctc accttcatgt acgtaacaac
     5941 aaatttcctc actactctta cttggaagaa tttcaattaa tcttggtagc attgtttttt
     6001 cctttaaact agatgataaa tgataatgta taaatgttga gttttctaca tcaaatactt
     6061 ctttttcata acttcttaat acagctcttt tatgctcttt tggcttcata aaaaagtaag
     6121 ttaattctac atctagtaca cttgctattt ttcctaagga atctgttgcc acacttgtta
     6181 atcctctttc aagttgtgat aaaaaaccaa ttgacaagtt tgttttttca ctcatatcct
     6241 tcagcgtcat ttgcttttga gttctgagtt gctttatttt tgctcctatg tccttattca
     6301 aaaccatcac ccctaaataa ttttaatttt ttcataatat aaatacaaaa atataaatat
     6361 aggtactgaa cctatcttta tttcatttaa aaaaattttt ataagtatta ctataattta
     6421 tcaatctttt tttgtctaca tttttacgat tatttacgat ttatttttca catatgtata
     6481 tttaatcttg ccaactaaag atacattttt tataagcatt tactctttat ataataaaac
     6541 ttaagttgtt catgagtctt cttctggttt aattattaaa atttcaaatt atattattat
     6601 ttctacacat tattacatcc ttt
//
LOCUS       DAEPKC010000148         6578 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.150, whole genome shotgun sequence.
ACCESSION   DAEPKC010000148 DAEPKC010000000
VERSION     DAEPKC010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6578)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6578)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6578
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.150"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..123
                     /locus_tag="KR294_003496"
     CDS             <1..123
                     /locus_tag="KR294_003496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBH0241543.1"
                     /translation="KNLNIREWICPSCNETHDRDINASINILKEGLRLITIQNK"
     gene            250..1419
                     /locus_tag="KR294_003497"
     CDS             250..1419
                     /locus_tag="KR294_003497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HBH0241544.1"
                     /translation="MNELCKDEVVEFCNRIKGKVESVAISGVFAPVNKQQEEEVAKWV
                     REILGDIPISLSNEIGNIGILERENGAILNSALSQVGKAVSLGFEKALKDLGIDAQIY
                     FSQNDGTLMNLEYTMKYPIFTIGCGITNSIRGASFLSKVKNAIVLDVGGTTSDLGVLY
                     NGFPRESSIPVTIGGVHTNFRMPDVLTIGLAGGTCVKGEKDNIKIGPESVGYRITEDA
                     IIFGGDTLTLSDVVTKLDMAFEDRKSNVENLDKEYCNEVYKKVILKLEDAVDQMKTSQ
                     DDVELVLTGGGSIIVPEKLKGISNVIRPPHYTAANAIGAALGQISGDVEKVYSLDKMS
                     REDAIEDAKKEAVNKALKAGAKEDTIEVLNIEDVPLAYLPGNALLIKVKVVGDLI"
     gene            complement(1582..2124)
                     /locus_tag="KR294_003498"
     CDS             complement(1582..2124)
                     /locus_tag="KR294_003498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HBH0241545.1"
                     /translation="MKSYIALLRGINISGKNKIIMSELKASFVELGYSEVSTYLNSGN
                     VVFLSDVDDSKVISNTIRLMIKKQFELEIPVFIISQEELKDILNNAPNWWGDNNKEIY
                     DNLIFMFPDLSYDEFYDEVGNPKEEYEKVYHYKNAIFWSFSRKDYKKTNWWSKTASSN
                     VSDKITIRTANTVRKIVGMR"
     gene            complement(2272..2556)
                     /locus_tag="KR294_003499"
     CDS             complement(2272..2556)
                     /locus_tag="KR294_003499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBH0241546.1"
                     /translation="MAKNTKQTTVHIDETLLKEVKRIGINENKSISQIINESIIDYIL
                     VYRENEDKEKNEHDKNLNETINEFKKEEEKRMQAKSAARAIAEAKKRVLY"
     gene            complement(2619..3383)
                     /locus_tag="KR294_003500"
     CDS             complement(2619..3383)
                     /locus_tag="KR294_003500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HBH0241547.1"
                     /translation="MNNYLKFATYQLIGFTSSIPRLIKIKKNPDKFSLKEKFEFMQKQ
                     AKKSLDIVNIELNIIGKETLPKEPLLFVVNHSSMLDSFILTASVERPIGCVIADEPVW
                     RNIPIFKEWAKLLRCVYVNRKNNREGIKSIAQASQNILTGQSMAVFPEGDLTWIKEPN
                     SLVSEFRSGALKIAYKAKCPIVPLVIKNSKDTYEGYQPIGKINSVPVEVEFLEPIYDH
                     IENPRLKSSVLGENIKNKMINTIENFRKSNKTFKEF"
     gene            complement(3665..3931)
                     /locus_tag="KR294_003501"
     CDS             complement(3665..3931)
                     /locus_tag="KR294_003501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HBH0241548.1"
                     /translation="MIESRCGILCYECGYKEKVNCKGCTEIEKPFWGEQCPVKSCCED
                     KNLTHCGLCDTFPCEMLNQFAYDKEQGDDGKRISQCKKWAVLAL"
     gene            complement(3973..4782)
                     /locus_tag="KR294_003502"
     CDS             complement(3973..4782)
                     /locus_tag="KR294_003502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0241549.1"
                     /translation="MNKIINNILNTCKQYTYILPHKLLRQYIAHYTISIPDTSIKENL
                     TLIPDASGCMIFKFDKKGIESAFWGATTKTTIVKNDIENVLFRVFVEFRPGGVYYLTG
                     LSQRESTDLKISLEDFNTLFSLEVNSIFERTSTIEELVEQLDMLFLSYLLKSNIVDMT
                     IPILENARKQNSIMSVKNISQISCYSERHLNRIFNNSLGMSVKSYLRLLRINLVLQEI
                     QNNKIPFATLAQDIGYYDQSHFINDFKSICGVNPTTYIKNLSDFYNEKYKF"
     gene            5095..5376
                     /locus_tag="KR294_003503"
     CDS             5095..5376
                     /locus_tag="KR294_003503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241550.1"
                     /translation="MASKQTPRNNLEKFLRIRVLSHTGDKIHIKLPVNFAKRMIENNA
                     LDLFNGKDDVVDGKKVTEILVKAFDYDLTGEVVHLERKNGDIIKVSIVQ"
     gene            5640..5894
                     /locus_tag="KR294_003504"
     CDS             5640..5894
                     /locus_tag="KR294_003504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241551.1"
                     /translation="MENKDFKLTICIFAFVIGVVVLFCCIGLGEFSAEHIIQQNGGIM
                     DTDQYNIYLDQSISQYRNFGSILALLGGIGILFDKYIRKY"
     gene            5939..6262
                     /locus_tag="KR294_003505"
     CDS             5939..6262
                     /locus_tag="KR294_003505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241552.1"
                     /translation="MATEIFTVKITPLEAQKMIKENLDADLVFSDSYNLGDDKFILIT
                     TFEKYYARNNSDAGLIVVYENTTGKTVIKATSTGSAIGILKIDWGAGGNLLKRVKNIL
                     ADYII"
BASE COUNT         2414 a          788 c          938 g         2438 t
ORIGIN      
        1 aagaacttaa atataagaga atggatttgt cctagttgta atgaaactca cgatagagat
       61 ataaatgcaa gtataaatat attaaaagaa ggattaagac taataacaat tcaaaataaa
      121 taacgtatgt aagaaccgga ggaactacgg ggatagcctg tggagaatta gtaagacata
      181 ttttagtatg caaaattctg tgaagcagga accctgtgac tttagtcatg ggaggttcag
      241 ggtagaaaga taaatgaact ttgtaaagat gaagttgtag agttttgcaa tagaataaaa
      301 ggtaaagtgg aaagtgttgc aataagtgga gtatttgctc cagtaaataa acaacaagaa
      361 gaagaagttg caaaatgggt tagagaaatt ttaggggata ttcctatatc tttatcaaat
      421 gaaataggta atataggtat attagaaaga gaaaatggag ctattttaaa ttctgcattg
      481 tctcaagtag gtaaagctgt atctttagga tttgaaaaag cacttaaaga cttaggtata
      541 gatgctcaaa tatatttcag tcaaaatgat ggaacattaa tgaatttaga gtatacaatg
      601 aaatacccaa tttttacaat tggatgtgga ataacaaatt ctataagagg agcttccttc
      661 ttatcaaaag taaaaaatgc aatagtatta gatgttggtg gaactacaag cgacttgggt
      721 gtactatata atggattccc tagagaatca tctattccag ttacaattgg aggagtacat
      781 acaaacttta gaatgccaga tgttttaact attggtcttg ctggtggtac atgtgtaaaa
      841 ggcgaaaaag ataatataaa gataggtcct gaaagtgtgg gatatagaat aactgaagat
      901 gcaataatat ttggtggaga cactctaact ttatcagatg ttgttacaaa attagatatg
      961 gcgtttgaag atagaaaaag caatgttgaa aacttagata aagagtattg taatgaggta
     1021 tataagaagg ttattttaaa attagaagat gctgtagacc aaatgaagac tagtcaagat
     1081 gatgttgaat tggttttaac tggtggagga agtataattg ttcctgaaaa actaaaaggc
     1141 ataagcaatg ttataagacc tcctcattat actgctgcaa atgctattgg tgcagcttta
     1201 ggacaaataa gtggagatgt agaaaaagta tacagtttag ataaaatgtc gagagaagat
     1261 gccatagaag atgcaaaaaa agaggctgta aataaagctc taaaagctgg tgctaaagaa
     1321 gatactatag aagtattaaa tatagaagat gttccacttg cataccttcc tggtaatgca
     1381 cttcttataa aagtaaaagt tgttggtgat ttaatttaaa gaataaatat aagtatttcc
     1441 agaattatat aaatatttct ggactcattt ttaaacttat tttatcaata aaaacagcat
     1501 aacttttgac tatattctta taagtttccg aacagccgat atatacctat tttttgaggt
     1561 ttatcggctg tttgttatct tttatcgcat tccaactatt tttcttaccg tatttgctgt
     1621 acgaattgta atcttatcac ttacatttga actggcagtc tttgaccacc aatttgtctt
     1681 tttataatct ttacgactaa aagaccaaaa gatagcattt ttataatgat atactttttc
     1741 atactcttct ttaggatttc caacctcatc ataaaactcg tcataagata agtcaggaaa
     1801 cataaaaata agattatcat atatttcttt gttgttatct ccccaccaat taggagcatt
     1861 atttagtata tcttttaact cttcttgtga aataataaaa actggtattt ccaattcaaa
     1921 ctgttttttt atcattaatc ttattgtatt tgagataacc ttgctgtcat ctacatcact
     1981 taaaaagaca acattaccac tattaaggta tgtagaaact tctgaataac caagttctac
     2041 aaagcttgct tttaattcag acataattat cttgttctta ccacttatat tgatacctct
     2101 taataatgcg atataacttt tcatataata atttcacctc taaacattca catttttcta
     2161 tgtagtacaa actggaattt gcatctttta taattctttc aaaacttctt catatgtaat
     2221 ttttttaata taaaaaaatc ggtgcttaat ttgtaccgat ttttgttttt cttagtaaag
     2281 aactcgtttt tttgcttctg ctatagctct agcagcactt tttgcttgca ttcttttttc
     2341 ttcttctttt ttaaattcat ttattgtttc atttagattc ttatcatgtt catttttttc
     2401 tttatcttcg ttttctctgt atactaatat ataatctatt attgattcgt ttattatttg
     2461 agatatactt ttattttcat taattcctat tctcttaact tccttaagta gagtctcatc
     2521 aatatgaacc gttgtttgct ttgtattttt tgccacctta atcacctctt aaaaaaaatt
     2581 ctaacattaa aatttttttt agtcaataaa ttttaatatt aaaattcttt aaatgtttta
     2641 tttgattttc taaaattttc tattgtattt atcatcttat tttttatatt ttcacctagt
     2701 acagaagact ttagtctagg attttcgata tggtcataaa ttggttctaa aaattcgact
     2761 tcgacaggaa cagagttaat tttaccaata ggttggtatc cttcataagt atcttttgaa
     2821 ttttttatta ctagtggaac aatagggcat tttgctttat atgctatctt taaagctcca
     2881 cttctaaact ccgaaaccaa tgaatttggt tctttaatcc atgttaaatc tccttctgga
     2941 aacactgcca tactttgacc tgtaagtata ttttgagagg cttgggctat actctttata
     3001 ccctcacgat tgttttttct gtttacatat acacatctta gtaattttgc ccattcttta
     3061 aatataggta tatttctcca aactggttca tctgcaatta cacatccaat tggtctttct
     3121 acacttgctg ttagtatgaa gctgtcaagc atactagaat gatttacaac aaatagaagt
     3181 ggttcttttg gcagtgtttc cttaccaatt atattaagct ctatgttcac tatatctaaa
     3241 gattttttag cttgtttttg cataaattca aatttttcct ttaagctaaa tttatcagga
     3301 ttctttttaa ttttaataag cctaggtata gaagatgtaa aacctataag ttgatatgta
     3361 gcaaatttta agtaattatt cataaaatta tctccttaaa ataaaattat ttattactgt
     3421 aaagatttta acataaaata aaatttaagt ctattttaat tcaattttgt aacatatatt
     3481 ttaaatagac agagattgag attttatatt tccaatttta gtaatcagat tttatcaata
     3541 aattactatt ctattaattt aattaaataa cctttaaatt taattataaa aactgttgca
     3601 gaaatttcta caacagttta aaaaatttac cttacaaaaa cttattttat aacaagagag
     3661 tatattataa ggctagtaca gcccattttt tgcactgaga aattcttttg ccatcatcac
     3721 cttgttcttt gtcatatgca aattgattaa gcatttcaca tggaaatgta tcacatagac
     3781 cacaatgtgt aaggttttta tcttcacaac aagattttac aggacattgt tcaccccaaa
     3841 atggtttctc aatctctgta caacctttac aattgacttt ttccttgtat ccacattcat
     3901 aacataaaat tccacatctt gattctatca ttttaagtca ctccttaaat ataaatttta
     3961 tatgattgta tatcaaaatt tatacttttc attgtaaaaa tcggacaaat tttttatata
     4021 ggttgttgga ttaacaccac aaatagattt aaaatcattt ataaaatgag attggtcgta
     4081 ataaccaata tcttgtgcta aagttgcaaa tggtatttta ttattttgta tttcttgtaa
     4141 tacaaggttt atacgaagta atctaaggta tgatttaaca ctcataccaa gagaattatt
     4201 aaaaattcta tttaaatgtc gttcactata acaactaatt tgtgaaatgt ttttaacaga
     4261 cataatagag ttttgttttc tagcattttc aagaattggt atagtcatat ctactatatt
     4321 tgatttcaat aagtatgata agaataacat atctaattgt tctactaatt cttctatagt
     4381 acttgttctt tcaaaaatgg aattaacctc taagctaaat aatgtgttaa aatcttcaag
     4441 tgaaattttt aaatctgtag attctctttg agaaagacct gtcaaataat atactccacc
     4501 tgggcgaaac tcaacgaata ctctaaaaag tacattttct atatcatttt ttacaatagt
     4561 agtttttgtt gtggctcccc agaatgcgct ttctatacct tttttgtcaa atttaaatat
     4621 catacatcca ctagcatcag gtattaatgt aagattttct ttaatacttg tatctggaat
     4681 agatattgta tagtgtgcta tatactgtct taacaattta tgtggcaaaa tatatgtata
     4741 ctgtttgcag gtatttaaaa tgttattgat tattttattc ataagtatat cctcctgata
     4801 tataaaaaat aagtatacta atttattttt tatataataa accagttttg ttttaattga
     4861 aatattctaa taagatattt tgttaaattt agatacaata attgtaaagt aaaatctcaa
     4921 aatatacaat tattataaat catagatatt tattaaataa atatattaaa gaagaaggaa
     4981 tataaaacaa gattagaaaa taatagtgtt actttcataa taaatacata taaagatatt
     5041 tttaagaata aaatttatta ttaaataaaa aataaaggag agtgatttaa tagtatggca
     5101 tcaaaacaaa caccaagaaa caatttagaa aagtttttaa gaataagagt attatcacat
     5161 acaggcgata aaatacatat aaagttacct gtaaattttg caaagagaat gattgagaat
     5221 aatgccttgg atttatttaa tggaaaagat gatgtagtag atggtaaaaa agttactgaa
     5281 atattagtta aggcatttga ctatgattta actggagaag tagttcactt ggagagaaaa
     5341 aatggagaca ttattaaagt ttcaattgta caatagaatt attttatatg aattttattt
     5401 ttgaatagtt ataaataatt agaaatttgt aaaaaagtat aatatattat tagtaatggt
     5461 acagaataca catttataat ttatagatgt gtattttttg tttaaaaaat ttaaatatat
     5521 aaaactataa aggttacaat tttggaaata gatgtaaata tatgttgtat tgtataataa
     5581 gagtaatata aaatctagta aaaataatca aataaattta gcttatgaga gggataacta
     5641 tggaaaataa ggattttaaa ttaacaatat gtatatttgc ttttgtaatt ggagtagtag
     5701 tattattctg ttgtataggt ttaggtgaat ttagtgcaga gcatattatt caacaaaatg
     5761 gtggaatcat ggatactgac caatataata tttatctaga ccaatctatt tctcaatata
     5821 gaaattttgg ttctatatta gctctgttag gaggaatagg gatattgttt gataaatata
     5881 tcagaaaata ctagagatta tgttttgtct aaaataaatt cttatgagga gataaaaaat
     5941 ggcaacagaa atatttactg taaaaattac acccttagag gcacaaaaaa tgataaaaga
     6001 aaatcttgat gcagatttag tttttagtga ttcttataat ttaggagatg ataaatttat
     6061 actaattaca acttttgaga agtattatgc aagaaataat agtgatgcag gattaatagt
     6121 agtttatgaa aataccacag gaaaaacagt tattaaagct acttcaacag gcagtgcaat
     6181 tggaatttta aaaattgatt ggggtgcagg tggaaattta cttaaaagag taaaaaacat
     6241 acttgctgat tatattattt aattatttta tctaactgat aatatgtcaa gaaaatctcg
     6301 taaaagaggt taagaacatt tttataatat atagataaat aagaatttga aggtaaagtt
     6361 tttaaggtat aaagaaaaat aatataataa aacgaattgg ctttataatt ctttataagg
     6421 caaagagcac atttctttat ataattgttg gatattaaat aatatgtaaa tacaccattt
     6481 acatataaaa atttaattaa tatgttaaga gaaaatgaaa tggaaattac taaaaaatat
     6541 ttttaaattg gataatggtt gatattatgt ttatacaa
//
LOCUS       DAEPKC010000149         6544 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.151, whole genome shotgun sequence.
ACCESSION   DAEPKC010000149 DAEPKC010000000
VERSION     DAEPKC010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6544)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6544)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6544
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.151"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            428..1702
                     /locus_tag="KR294_003506"
     CDS             428..1702
                     /locus_tag="KR294_003506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HBH0241553.1"
                     /translation="MQFMDVSKYIEGANLKVKTKNGETVKRIYFNNSATPLVLKNVVD
                     NLNCEIPWLTYINAPGIISEKNTLKYENVRSTILKLIDGDEEKDSVIYVKNATEGINF
                     LAKFFKDENPDKFVITTAMEHMANYLPFKVNFPTKVVGITEKGELDLCQLENILKNYA
                     GNVSLVTVTGASNVTGITTPIYEIARIAHKYGAKILVDIVQVIQHKPFSMMPHECDEH
                     IDFVVFSAHKCYSPLNGGALVGPKKFFEKFNPVLYGSGSTKFVNDNKILYANVPQRFE
                     AGYPEYFGTLAMGKALNTLNKIGLNRISKYERELFLYAKEEMSKIPNIIIYGDKSNNV
                     IIPNISFNISNMYYKDVAKYLVDNFGIETGAGVVGADIYVQKLLGINPKEAYVRFMRE
                     NPVGLVRISLGMYNTFDEVDSFIHAIKTLAFK"
     gene            complement(1909..2226)
                     /gene="trxA"
                     /locus_tag="KR294_003507"
     CDS             complement(1909..2226)
                     /gene="trxA"
                     /locus_tag="KR294_003507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HBH0241554.1"
                     /translation="MVKIINNNEFINEVENKDGLVVVDFFATWCGPCKMLSPIYEALG
                     NEMVEKANFLKVDIDQSIELAQKFEVSTVPTMLIFKDGKPVDRLIGFMPKENLKNKIE
                     SYM"
     gene            2493..3245
                     /locus_tag="KR294_003508"
     CDS             2493..3245
                     /locus_tag="KR294_003508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrmB family transcriptional regulator"
                     /protein_id="HBH0241555.1"
                     /translation="MDNIINELQNIGFTKYESQIYISLLKESPLTGYEISKLSGVPQS
                     KVYENITKLLNNNIIINVGTDPIKYIPINPNELLKNKKKEFDNSMDNLKNSLQILNKS
                     KSVEYVLNIKGDKNILKKAIEMIKNAKQEIIISCPYEEILELKKELLIAYKKNINIEI
                     LLLENKSLKGLDNIHIHGGNKTTLENKMLYKGIILIVDNDEILTGNLSEGSEAISIWT
                     KNSNILYIGVQYIKHEIYISEQIKGGYKNEQN"
     gene            3232..4113
                     /locus_tag="KR294_003509"
     CDS             3232..4113
                     /locus_tag="KR294_003509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HBH0241556.1"
                     /translation="MNKIKIKQVDAFTTIPFGGNPAGVVTDASNISDEIKQNVAKEMN
                     LSETAFVSESNIADFKVQFFTPGLEVDLCGHATIGTFHALLEEGKLNTNKSIFYQETK
                     AGVLSVELKKINNENIFMMEQNTPEFENLDNCRKELAQMIGVHEDRLLEYPIIKVNTG
                     LWWLVFGLKSLDDLKNISPDLNKIKKFSGDNNIIGITPFCIETIDKKCDYHLRSIAPY
                     VGVTEDPVCGTGNACVSSYIVHHNILDKTSFIGEQGNFINRPGKVYVNITRENNDITS
                     VKIGGSAYTILSGEIMY"
     gene            complement(4339..5694)
                     /locus_tag="KR294_003510"
     CDS             complement(4339..5694)
                     /locus_tag="KR294_003510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HBH0241557.1"
                     /translation="MSSTVKKKGKFPMGFYICSTTFSFERAAYYASKYLIYIFLTTAI
                     VHGGLGIDKGQAAIMQANLVAFTYLAPIIGGYISDRWIGARYTIPIGMLIMGVGYYLG
                     SIATTVSMVNAMIILVSIGTAFFKGNVSAVNGQLFDSQEELDTAFSVQYSFVNIGSFI
                     GTIAVGILYLKTFAKNGVLGFSQCFFIAAVLCVIGAIWFIYGWRFLGNAGKRPFKEGV
                     VAEKIEEKDKSPLTSMDKKRIWAIILISFFSVIFWVFWYLTYLAVYDYGAAFVNMNVG
                     GFDVPLAWFDSLNSLVCIVLGPVLGALWFKLASRPQGDMSLFKKTGLGLIFLGLAFLM
                     LVGAEFSRGVGAPETAKASILWIIMFGILLSLGEMLFSPLGNSFVSKYAPKKLLGVLM
                     GVWTFATFIAGKGYGYIYAFTLKFDMIKVYTIIPVILFVAAILLFLSDKTLSRLVEDD
                     K"
BASE COUNT         2519 a          944 c          821 g         2260 t
ORIGIN      
        1 tatacttgta catcttttat aacatataaa atcttttttt ctaattatat acaatatatt
       61 ttccattatg ttctaatcaa tttctttact atttttacaa ctttattagt catattcata
      121 attatttcta attagtgttt aacattttat gtaaaattta taaaaaaatg tatataaatt
      181 aaaataagtg actatactaa aaatatgata cggataaaca ataagttcaa cctatctccc
      241 ccaaaatcaa gtgagctaca gtttccccca actgtagctc attttcgtgt aatttaataa
      301 acatctcaac aagaattaat taacaaaacc ccttataaaa acataacata tattaaacaa
      361 gctcttgatt aaaacttgag cttttttaat aaaaaacaga atagtttatt agataagggg
      421 tttttttatg caattcatgg atgtatctaa atacattgaa ggtgcaaacc ttaaagttaa
      481 aactaaaaat ggtgaaactg ttaaaagaat atattttaac aactctgcca ctccattagt
      541 tttaaaaaac gtagtggata acttaaactg tgagattcct tggcttactt atattaatgc
      601 tccaggaata atctcagaaa aaaatacttt aaaatatgaa aatgtacgct ctactatcct
      661 caaacttatt gatggagacg aagaaaagga ttctgttatt tatgtcaaaa atgctacaga
      721 aggaataaac ttcttagcaa aattttttaa agatgaaaat ccagataaat ttgttattac
      781 cacagcaatg gagcatatgg ctaattacct gccttttaaa gttaattttc ctacaaaagt
      841 tgttggaatt acagaaaaag gagaacttga tttatgtcaa ttagagaata tacttaaaaa
      901 ttatgctggt aatgtatctc tcgttacagt tacaggagct agtaatgtca caggtataac
      961 cactcctata tatgaaatag caagaatagc tcataagtat ggtgcaaaga tattggtgga
     1021 tattgtgcaa gtaattcagc ataaaccttt ttcaatgatg ccacatgaat gtgatgagca
     1081 tatagatttt gttgttttta gtgctcataa atgttattct ccactaaatg gaggagctct
     1141 ggtaggacct aaaaaattct ttgaaaaatt taatcctgta ctatatggct caggttctac
     1201 caaatttgta aatgataaca aaatactata tgcaaacgta ccccaacgtt ttgaagcagg
     1261 atacccagag tattttggaa ctcttgcaat gggaaaagca ctgaacactt taaataaaat
     1321 tggtctaaac agaatttcaa aatacgaaag agaattattt ttatatgcta aagaagaaat
     1381 gagtaaaata cctaatataa taatatatgg agataaatca aataatgtaa ttatcccaaa
     1441 tatatctttt aatataagta atatgtatta caaagatgta gcaaaatatt tagttgataa
     1501 ctttggaata gaaactggag ctggagtagt aggtgcagat atttatgtac aaaaattatt
     1561 aggtataaat ccaaaagagg catacgtcag atttatgagg gaaaatcctg taggtcttgt
     1621 taggataagc ttaggaatgt acaatacttt tgatgaggtg gatagcttta tacatgctat
     1681 taaaactttg gcttttaaat aagatttttc tattcttttt tatcaataaa tagagagtag
     1741 ttttgttttc acaaaaaaac aaattatatc aacagtcaat ttcattagca attagacact
     1801 catttgtaac tatacaaact attttacact atacaaacaa aaaactcatt acaatgagtt
     1861 tttttgttta tatatgagat ttattttaat tacttcaatt tactttaatt acatatatga
     1921 ttcaattttg ttttttaaat tctccttagg cataaaacct attaatctat ctacaggttt
     1981 tccatcctta aatattagca tagttggtac tgtagatact tcaaatttct gagctaattc
     2041 tatactttgg tctatgtcca ccttcaagaa gtttgctttt tcaaccatct catttcctaa
     2101 agcttcatat attggtgata gcatcttaca aggtccacac caagtcgcaa agaaatctac
     2161 aactactaaa ccatctttat tttctacttc atttataaat tcattattat ttattatttt
     2221 taccataata tacatctcct ttattatctt cttgatatta atatactacg ccctatataa
     2281 cagttcaatt aggcactttt ttgtaaccgc ctatttttaa tagatttaat attatgataa
     2341 atagatttat aagattaaat atttatgaga ctaaatattt ctaatatatt ttattttttt
     2401 cttaatatag ttgacatttt ttcccttaaa ttataaaatc aaattaataa ctacataggt
     2461 agttactaat cttttatcaa aggagtttct atatggataa tataattaat gaattacaaa
     2521 atataggatt tactaaatac gaatctcaaa tatacatatc attattaaag gaaagccctt
     2581 taacaggata tgaaataagt aaattatcag gtgtaccaca atcaaaagtc tatgaaaata
     2641 taacaaagct attaaacaat aatataatta tcaatgttgg aactgaccct attaagtaca
     2701 taccaataaa ccctaatgaa ttattaaaaa ataagaaaaa agaatttgac aattctatgg
     2761 ataatctaaa gaatagctta cagatattaa ataaaagtaa aagtgtagaa tacgtattaa
     2821 acataaaagg agataaaaat atattaaaaa aagcaataga aatgataaaa aatgcaaaac
     2881 aagaaattat aatttcttgc ccttatgaag aaattcttga attaaaaaaa gaactcctaa
     2941 ttgcttacaa aaaaaatatt aatattgaaa tactactttt agaaaacaaa agtctgaaag
     3001 gtcttgataa tattcatatt catggaggta ataaaactac acttgaaaat aaaatgcttt
     3061 acaaaggaat tattttgatt gtagataatg atgaaatatt gacaggaaac ttatcagaag
     3121 gcagtgaggc catttcaatt tggacaaaaa actctaacat tttatatatt ggagttcaat
     3181 acataaaaca tgaaatttat atttcagaac aaataaaagg aggttataaa aatgaacaaa
     3241 attaagatta aacaagttga tgcttttaca actatacctt ttggtggaaa tcctgctggt
     3301 gtcgttactg atgcctctaa catttctgat gaaattaagc agaatgtggc taaagaaatg
     3361 aatttatcag aaactgcatt tgtttcagag tcaaatattg cagattttaa agtacaattt
     3421 ttcacaccag gtttagaagt tgatttatgt ggtcatgcaa caataggtac tttccatgca
     3481 cttttggaag aagggaagct taatactaat aagagtatat tttatcaaga aacaaaagct
     3541 ggtgtattat ctgtagagct taagaaaata aataatgaaa atatatttat gatggaacag
     3601 aatacacctg aatttgaaaa tttagataat tgcagaaaag aacttgcaca aatgataggt
     3661 gtgcatgaag atagacttct tgaatatcct attataaagg taaatactgg actttggtgg
     3721 cttgtatttg gtctaaaatc tttagatgat ttaaaaaata tctctccaga tttaaataaa
     3781 atcaaaaaat ttagtggtga taataatata attggtataa ctccattttg tatagaaact
     3841 atagataaaa agtgtgacta ccatttaaga tctatagcac catatgttgg agttacagaa
     3901 gaccctgtat gtggaactgg gaacgcttgc gtatcatctt atatagtaca tcacaatatt
     3961 ttagataaaa ctagttttat tggtgagcaa ggtaacttta taaacagacc tggaaaggta
     4021 tatgtaaata taactagaga aaacaatgac ataacttctg taaaaattgg aggaagtgct
     4081 tatactattt taagtggtga aattatgtat taatcccata cctaataaaa acaaataaaa
     4141 atactagcta actaaagcta gtatttttat ttgttatttt tatttaataa tcatactcta
     4201 acaaatatta taattatata tatcataata ttgtatttag aagtaaaatt ttatttttat
     4261 tattaattag ttataaatca atctaataca acataattac agtagattaa cctataaaac
     4321 ataataattg cttactaatt atttatcatc ctcaacaagt ctacttaatg tcttatcaga
     4381 taagaataat aatatcgctg caacaaatag tattactgga attatagtat atactttaat
     4441 catatcaaat ttaagagtaa atgcatatat atatccgtat cctttaccag ctataaaagt
     4501 agcaaatgtc catactccca taagaacacc tagaagcttc ttaggtgcat acttacttac
     4561 aaaagagtta ccaagtggtg agaataacat ttcaccaaga cttaaaagaa taccaaacat
     4621 gattatccat agtatactag ctttagcagt ttcaggagct ccaacccctc ttgaaaattc
     4681 tgcaccaaca agcattaaga atgcaagacc taagaatatt aatccaagac ctgtcttttt
     4741 aaataaactc atatctcctt gtggtctact agcaagttta aaccataatg ctccaagaac
     4801 tggtcctaat actatacata caagtgaatt taatgagtca aaccaagcaa gaggaacatc
     4861 aaatcctcca acattcatgt ttacaaatgc tgcaccataa tcataaactg caagataagt
     4921 tagataccag aatacccaga aaattacaga gaagaatgat ataagtataa tagcccaaat
     4981 tctcttctta tccatgcttg taagaggaga cttatctttt tcttcaattt tttcagcaac
     5041 tacaccttct ttaaaaggtc tctttcctgc attcccaagg aatctccatc catatatgaa
     5101 ccatattgca cctattacac aaagtacagc tgctataaag aaacattgag aaaatccaag
     5161 tacaccattt tttgcaaatg ttttaaggta aagaatacca actgctatag taccaataaa
     5221 agaacctata ttaacaaaag aatactgtac tgaaaatgct gtatcaagtt cttcttgact
     5281 atcaaaaagc tgtccattta ccgcagatac gttaccttta aagaatgcag taccaattga
     5341 aactaagatt atcattgcat ttaccataga aactgtagtt gcaatagaac caagatagta
     5401 tcctactccc atgataagca tacctatagg tatagtatat ctagctccta tccatctatc
     5461 tgatatatat cccccaatta taggtgcaag gtatgtgaat gcaacaaggt tggcttgcat
     5521 tatagcagct tgtcctttat ctattccaag accaccatga actatagctg ttgtaaggaa
     5581 tatatatatt aagtactttg aagcataata tgctgctctt tcaaatgaga aagttgttga
     5641 gcagatataa aatcccatag gaaatttacc cttctttttt actgttgagc tcataatttt
     5701 aaatcctttc ttaattgtat ttttattttt tacgttttgt ccaaattctt tcttttatga
     5761 aagatataat attattattt tgtaaaacaa tttgtaatta ttattaagat aattgcgcat
     5821 ttatttgtag agtacatatt ctcatggaat aaaattaata cacttcttaa tcataaattt
     5881 aaattatata aattcactat tttcagatat agttataaat taatatattc tcatctaata
     5941 ccatgaaaaa accttcgcca tatgcaattc ttatttttta cgtgatagta ttttacaaac
     6001 taaaatcccc cttttgtagc aacttatgta attacatttt agtgcttttt taaaggagtc
     6061 tcgaataaag caacatatat tttgttcaaa taatgttttt atttattttt taaatttata
     6121 tattacttca ctcaaccaat tctcaactta aataactaaa ctactatcta ttcacagatt
     6181 aggcttattt cttacacatt agtttataat aaacactgtg aatctaaaca taaaaactgt
     6241 tattttaaag taattaccca tatattcgct ttgatactat ttattgaggt tatactcttt
     6301 atgtataata tattatttat aaaatacctc aaaatatatt attcataaaa tacctcaaac
     6361 tgaaaacttt ttcacgaata tttatttttc acctcccctt ttttatttca ccatgtaaat
     6421 cgtaccataa atatgcactt atatgcaaga aaaaaatcta ttaatcgaca gtaaataatt
     6481 agaaaaattc aaattatatt tatcaagtat attatataaa atatttccta tgaaaatata
     6541 aatt
//
LOCUS       DAEPKC010000150         6446 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.152, whole genome shotgun sequence.
ACCESSION   DAEPKC010000150 DAEPKC010000000
VERSION     DAEPKC010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6446)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6446)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6446
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.152"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..481
                     /locus_tag="KR294_003511"
     CDS             <1..481
                     /locus_tag="KR294_003511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBH0241558.1"
                     /translation="AKLQRELSRKTIGSLNRNKARLKVARLQEHIANQRNDFLQKLST
                     KLIKENDIICIEDLQVKNMIRNRKLSRSISDVSWSEFIRQLEYKANWHGRQIVKVGKF
                     FASSQICNKCGYKNEEVKDLNIREWIYPSCNETHDRDINASINILKEGLRLITIQNK"
     gene            913..1167
                     /locus_tag="KR294_003512"
     CDS             913..1167
                     /locus_tag="KR294_003512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241559.1"
                     /translation="MENKDIKLTICIFAFVIGIIVLFCCIGLGQFNMDCIIKQNGGSI
                     ATEQYNIYLEQSISQYRNFGSILVLLGGIGILFDKSVRKY"
     gene            1203..1526
                     /locus_tag="KR294_003513"
     CDS             1203..1526
                     /locus_tag="KR294_003513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241560.1"
                     /translation="MARDVFSVKMTPLEAQKMVEKNLEADLVSVDIYNLENNKSIIVT
                     IFEKYYARSNSDAGLVVICENTTGKTLVKITSTGSAIGLFQIDWGTGNNLIKRVKKIF
                     IDYII"
     gene            1800..1952
                     /locus_tag="KR294_003514"
     CDS             1800..1952
                     /locus_tag="KR294_003514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241561.1"
                     /translation="MDNFLFNVLASVTASYIVYLISKLIKKVKSHSTAKSDLKIDINF
                     KYHRKK"
     gene            2146..3069
                     /locus_tag="KR294_003515"
     CDS             2146..3069
                     /locus_tag="KR294_003515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHOCT domain-containing protein"
                     /protein_id="HBH0241562.1"
                     /translation="MVGAFVLPNYAIILSEMSNLWGNFIMWILVPIITIVLLIIAVSS
                     MQYILVMIAFLLIIYSFIEKKIVMGLVSVLFFTYSIYLCATWEDKSLIADNKVETVKA
                     QRETVEREKEMERRRIQEEVDKERYIEKHGMEISENDLKVKLEALVPQEYKGKKYELK
                     VGKFKRYSMYFDLTVQNEKFSNSEECKKFVKEIANDLKKIKISKAYFKFHSKDDGGIY
                     NSVYIDYFRNIQNNVDNVENLEFNEFELKTEEEEKREQEKIEQEKNSYNNYIQNRVVD
                     PLDRIKKLKELLDSGAITQEEYNKKKKELLE"
     repeat_region   3336..4016
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=3336..3363
                     /rpt_unit_seq="gttttagattaactatatggaatgtaaa"
     gene            4208..4360
                     /locus_tag="KR294_003516"
     CDS             4208..4360
                     /locus_tag="KR294_003516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241563.1"
                     /translation="MKNRRKDKRGFSVLLDKEKLDKFDEVLEEKNLTKKEWLEEKIDE
                     ELEQKE"
     gene            4480..5294
                     /locus_tag="KR294_003517"
                     /pseudo
     CDS             4480..5294
                     /locus_tag="KR294_003517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894376.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="toxin Bro"
     gene            5346..5507
                     /locus_tag="KR294_003518"
     CDS             5346..5507
                     /locus_tag="KR294_003518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241564.1"
                     /translation="MCENLLDNMYIEKRKEEYRIKLLKIRETDIDIYNKLESIVYKLS
                     EKKLEKNNK"
     gene            complement(5836..6300)
                     /locus_tag="KR294_003519"
     CDS             complement(5836..6300)
                     /locus_tag="KR294_003519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241565.1"
                     /translation="MDFGEVKSELSDKDLKDNEEALNKYKKYYLKVYKYYSEMDSIKS
                     IQDIEIEQSRLKGQLQKNSNPIFALYISIMAVVFSTTINLTFDLSDITNYFIRMIMTL
                     LFIVLLIFLVNKGILPIAIPYRNNIQFYTTALDVLEDMKKKILRERKYKKRR"
BASE COUNT         2651 a          610 c         1114 g         2071 t
ORIGIN      
        1 tgctaaatta caaagagaat tatcaagaaa aacaatcggt agtttaaata gaaataaagc
       61 aagattaaaa gttgcaagac ttcaagaaca tatagctaat caaagaaatg attttctaca
      121 aaaactatct actaaattaa taaaagagaa cgatattatt tgcatagaag atttacaagt
      181 aaagaatatg attaggaatc gtaaactatc tcgctcaatt tctgatgtgt catggtcaga
      241 gtttattcgt caattagaat acaaggctaa ttggcatggt agacaaattg taaaggtggg
      301 taaattcttt gcaagttcac aaatatgcaa taaatgtggg tataaaaacg aggaagtgaa
      361 ggacttaaat ataagagaat ggatttatcc tagttgtaat gaaactcacg atagagatat
      421 aaatgcaagt ataaatatat taaaagaagg attaagacta ataacaattc aaaataaata
      481 acgtatgtaa gaaccgtagg aactacgggg atagcctgtg gagaattagt aagacatatg
      541 ttagtatgca aaattctgtg aagcaggaaa cctgtgactt tagtcatggg aggttcaggc
      601 tagtattact cattattgta ttcaaaagct aaagtggaaa cctagtgaat atatgaattt
      661 agaagttaat gagagagcat tagcagccga ctcaatactt attaaaattg aagatgaaga
      721 agaaacaatg aaagaagctg aaagagagaa aaagagaggt agaagaaggt agaatttaaa
      781 gttaaaatag ttacattgct aatatatgaa aatgttacaa atttggaaat agatggatat
      841 atatgttgta tagtataatg tagataatat atcaccaagt aaaaaacaac aaataaatct
      901 aaattatgag gggtggaaaa taaagatatt aaacttacaa tatgtatatt tgcttttgta
      961 attggaataa tagtgttatt ttgctgtata ggtctaggtc aatttaatat ggattgtatt
     1021 ataaaacaaa atggtgggtc aatagctacc gaacaataca acatatattt agaacaatct
     1081 atttcacaat atagaaattt tggttctata ctggttttac taggaggaat aggaatactg
     1141 tttgataaaa gtgtcagaaa atactaaaaa agtatatttt tatttaggat gtgatgaatg
     1201 atatggcaag agatgtattt agtgtaaaga tgacaccact agaagcacag aaaatggtag
     1261 aaaaaaattt ggaagcagat ttagtttctg ttgatattta taacctagaa aataataagt
     1321 ctataatagt tacaatcttt gaaaaatatt atgcaagaag caatagtgat gcaggtttgg
     1381 tagtgatttg tgaaaatact acaggaaaaa cacttgttaa aattacctca actggtagtg
     1441 caattggact atttcagatt gattggggaa caggtaataa tttgattaaa agagtaaaaa
     1501 aaatatttat tgattatatt atttaattat tttatgtaga tattcttagg ttggtatgga
     1561 atttgtacta acctattaag taatcaataa aactaaataa acatagaaag cacttacaaa
     1621 tatgtaggtg ctttttattg aaaaaataga aaataaaata aaaagtaaga tataggaaaa
     1681 atatgtaaga attatatgtt ataataattg tagcaagaag atgtaatcta caatttatag
     1741 agtggagttc atgtattaaa aaattatcct cccaacgata agaagggagg tgaatataca
     1801 tggataattt tttatttaat gtgttagcta gtgtaacagc tagttacata gtttatttga
     1861 ttagcaagtt aatcaaaaaa gtaaaaagcc actctaccgc aaagagtgac ttaaagattg
     1921 atataaattt taaatatcat cgtaaaaaat aactttcagt tatagaactt cactctaccg
     1981 caaatagatt gtagttcttc ttgtttttat tataccacaa attagaaaaa atattgcata
     2041 taatattttt tatagtcaat aaaaatatga aattttttat acacaatgat gatgaatcta
     2101 actagatgaa taaatttaat tgtaaataag aaagtactta cttaaatggt aggtgctttt
     2161 gttttgccaa attatgctat aatattgagt gagatgagta atttgtgggg gaattttata
     2221 atgtggatat tagtaccaat aataacaata gtattactta taatagctgt ttcttctatg
     2281 caatatattt tagttatgat agcttttttg ttgattatat attcttttat agaaaagaaa
     2341 atagttatgg gtcttgtgtc agttcttttt ttcacttatt caatttatct ttgtgcaact
     2401 tgggaagata aatccttgat agcagataat aaagttgaga ctgttaaggc acaaagagaa
     2461 actgtagaaa gagaaaaaga aatggaaaga agaagaatac aagaagaagt agacaaagaa
     2521 agatatattg aaaaacatgg aatggaaata tcagaaaatg atttaaaagt taagctagag
     2581 gctttagtac ctcaagaata taaggggaag aaatatgaat taaaagtagg aaaatttaaa
     2641 agatatagta tgtattttga tttaactgta caaaatgaaa aatttagtaa ttctgaagaa
     2701 tgtaaaaaat ttgtaaaaga aattgctaat gatcttaaaa aaattaaaat aagcaaggcg
     2761 tactttaagt ttcattcaaa agatgacggc ggtatatata attctgttta tattgattat
     2821 tttagaaaca tacaaaataa tgtagataat gttgaaaatt tagaattcaa tgagtttgaa
     2881 cttaaaaccg aagaagaaga gaagcgagaa caagagaaaa tagaacaaga aaaaaacagt
     2941 tataataact acattcaaaa cagagtggtt gacccactag atagaataaa gaaactaaaa
     3001 gagttgctag attcaggagc aattacacag gaagaatata ataaaaagaa aaaagaatta
     3061 ttagaataga taatatagta agcacttaca agtatgtagg tgcttttaaa tttacaaagt
     3121 attccatttt aattttatag tttagatttt atgatataat aaaaatatag aagttttgca
     3181 gtgtgcgata tttgttacaa agtagggctt aatacttgaa atctaagatg ttgagggtgc
     3241 gtgataagtg ttatcaattg cactattgcc cgctcactgc aattttaaga gtattgtata
     3301 tatgtaggta ttggaaatgc taagtttatt ttggggtttt agattaacta tatggaatgt
     3361 aaaactgact cgggagcata taataagtaa tatcaagaat agttttagat taactatatg
     3421 gaatgtaaaa ttcgtaaaat aacaattgtc aggaatatga gaagtttgtt ttagattaac
     3481 tatatggaat gtaaaattgg actcaaaata taagttaaaa aaatttttaa gttttagatt
     3541 aactatatgg aatgtaaaaa tttttgacgc tatgaagaaa tttactacaa aatttgtttt
     3601 agattaacta tatggaatgt aaaaactttt ttcatcctcc caaacctctt gttcgctgtc
     3661 gttttagatt aactatatgg aatgtaaaaa agaaaataag tttaaaaaaa ggtttcatta
     3721 ttatatcgtt ttagattaac tatatggaat gtaaaaccaa ttatgtacag tttagttact
     3781 gtgttaagtc ttgttttaga ttaactatat ggaatgtaaa atccttttat aaatatcttc
     3841 tgacatgtgt atatgcttgt tttagattaa ctatatggaa tgtaaatcgg ctacaacggt
     3901 ataaattaaa tttagcaggg tacattttag attaactata tggaatgtaa attgctgtga
     3961 tttcaataat aaaacaatta ataattgtgt tttagattaa ctatgtggat tcaaaattaa
     4021 ataaacaaag aaagcactta caaatatgta ggtgctttta ttctgctcaa aattggtcgg
     4081 ttgggtaaaa taattagaaa aagttagtaa aaacctattg actgtaactc gttacaatat
     4141 tgttattaat gtaacgagtt acagaaaaga ggtgaataaa atagcaacta aaagtagggc
     4201 agagtatatg aaaaatcgtc gaaaagataa aagaggtttt agtgtacttt tagacaaaga
     4261 aaagttagat aaatttgatg aagtgttaga ggaaaagaat ctaaccaaga aagaatggct
     4321 agaagaaaaa atcgacgagg aactggaaca aaaggaataa aaaataaggg tcactcccac
     4381 cgaccaaagt ttgagtaacc cctatgacgt atactatcgt atatcaatta tagtatatgt
     4441 cattccttaa aaaaatcaat tattaaggag tgtaatatta tgaaaaatga attaatgatg
     4501 tttgaaggaa aagagattga agtatttgaa tttgaaggaa gaattttatt caactcaaaa
     4561 gatgtagtaa actgtttaga cataaaaaat gttaatgaga atataagact tatgaatgaa
     4621 aagcaagttg taaagttaag aaattcggat atcagtaata ctgacatccg aaaacttaat
     4681 aatgctggag aaaattttct tactgaaagt ggagtgtata aattaatctt taaatcaaga
     4741 aaagaagaag ctgagagatt ccaaggctgg ataagtgatg aagttttacc aagcataaga
     4801 caaactggtg catacataaa taataatgca ataccgaaaa gttgagagaa aaagcaagtg
     4861 agattgaaaa attacagttg gtttataaca gtacatctat gttaaaagaa ttgctagatg
     4921 atgcaggctt tgacaataaa tcaaaactat taacagctaa aacattatat aagaaagcag
     4981 gaattgattt accaatagag ataaacgaag aagaacatta ttttgataca aaacaaatag
     5041 catctaaact gaaaatatat tctaagagta ataaaccagc tcagatggca gtttgtgaga
     5101 ttattaaaaa gattgattta gaagatggtg aagttaaagg tgtttgggaa attaatggtt
     5161 cttggactgg tactgtaaat aaatatacaa agagtgtaat agataaggtg agaacttgga
     5221 tagaggaaaa taatagacct accaagattg caggtgagaa gaagaattat tatgtatttt
     5281 acaaaattga gtaaatttat cagttgtatt aaataattta gtttagtttt ggggggatta
     5341 atacaatgtg tgagaattta cttgataata tgtatattga aaagagaaaa gaagaatata
     5401 gaattaaact tttgaaaata agagaaacag atatagatat atataataag ttagaaagta
     5461 tagtatataa actttctgag aaaaaattag agaaaaataa taaatagaca tataaagcac
     5521 ttggatattc tactgtttca agtgctttgt ttggtataaa atggtataat ggagatagag
     5581 aattatatta acccaaaaat ggagaaaata gagaagatga tttagttgac gctttatcag
     5641 taggagtact tgcaggtaag acagaatctc tagtactatt agttggaaat ggaataagtg
     5701 atactcaaaa aagtttaata aataaaagag aatttagaaa tataactcaa attggtggaa
     5761 atggaaatga gaaagcattt agtgaagtag aaaacttagt taaatagatt agaaggtagc
     5821 aactagagtt ggttgttacc ttcttttttt atactttctc tctctaagta ttttcttttt
     5881 catatcttct aatacatcta atgcagtagt ataaaattgt atattatttc tataaggtat
     5941 agctattgga agaatgccct tgttaactaa aaaaataaga agtacaataa ataaaagtgt
     6001 cataatcatt ctaataaaat aattagtgat atctgataaa tcaaatgtta agttaattgt
     6061 tgtagaaaat acaacagcca taatagatat atacaaagca aaaatggggt tactattttt
     6121 ttgtaactgt cctttaagcc tagattgctc tatttctata tcttgaatac tttttatgga
     6181 atccatttca ctataatact tataaacttt taaataatat tttttatact tgtttaaagc
     6241 ttcttcatta tctttaaggt ctttgtcact taactctgat ttaacttccc caaaatccat
     6301 aaaatccctc ctacaatgtt atataatata ctttaattta tagcatattt aagaacttat
     6361 atcagcaatt tgtcgaacga ttttagctaa aaatagagta taatgatagg cttattattt
     6421 ataagatatt attttttata tagtta
//
LOCUS       DAEPKC010000151         6439 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.153, whole genome shotgun sequence.
ACCESSION   DAEPKC010000151 DAEPKC010000000
VERSION     DAEPKC010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6439)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6439)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6439
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.153"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            235..1179
                     /locus_tag="KR294_003520"
     CDS             235..1179
                     /locus_tag="KR294_003520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase regulatory
                     subunit"
                     /protein_id="HBH0241566.1"
                     /translation="MKFLRIEDEVIYSKKRYKLKREIDKLFLDEEYFQIEPQLFEEYD
                     EFTTINNKIPEESMVKVVNGKVMVLRADITTSIIKSLVPRWEDGLKLKLFYNSSIYKN
                     KNTVGIKEIRQIGCEYLGEASVEADREVVKLALKILEKYNNNFILEVGSSKYIHGLLE
                     ELNLNKNCENQIKNLLYTKNTHELKVYIEELKIKREVKELLSNILSLQGNLYNVIEKS
                     NKFYCNNKMKQALEELKQVNNLIEECNFLDKARFDLSMITMLDYYEGIMFRGYYPNSY
                     KEILSGGRYDSLTKEYGKEIPAIGFTLSVDELMKYVYK"
     gene            1201..1827
                     /locus_tag="KR294_003521"
     CDS             1201..1827
                     /locus_tag="KR294_003521"
                     /EC_number="2.4.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase"
                     /protein_id="HBH0241567.1"
                     /translation="MDYLTIALAKGRIEGESFKKFKKMGLGDSIDTDTRKLIFKDEEN
                     KIIYIHVKPSDVVTYVEKGVADLGIAGKDTILENETDVYEIYDLGFGKCKFAVAGLKG
                     DSIYREDEYLKVATKYPNIAKKYFKEKGQKIEIIKLNGSVELAPIVGLSDVIVDIVET
                     GNTLKANGLEILEDICNISARIISNRASYRFKYEQIQNIIRLFEELDN"
     gene            1861..2910
                     /gene="hisC"
                     /locus_tag="KR294_003522"
     CDS             1861..2910
                     /gene="hisC"
                     /locus_tag="KR294_003522"
                     /EC_number="2.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate transaminase"
                     /protein_id="HBH0241568.1"
                     /translation="MREKESIRELKGYEPNHVNCKVKLDANEGSKRLFKYLIKEISDS
                     DIDLNLYPEDSYSDLKESIIDYINISGVNKKNLLVGNGSSEIIDLIIHTFVDKDEVIL
                     SFSPSFSMYSIYSQINGSKFIGVESDENLVINIDNVIEKVKENNPKIVIVCNPNNPTG
                     TILKREEIIKLLDSTNSLVVLDEAYMDFGEESMLSDVFKYDNLIVLRTLSKAFGLAGI
                     RTGYMLSNSSLINSVEKVRPPYNLNSLSDFIATRALRNKDVVKAYIKEVKEEREVLYK
                     EMIGMGIKAYKSQANFILFYSEIENLSQKLIDRGVLIRKFGGKLENYYRVTIGDKEEN
                     SMFVGAIRDILKKEK"
     gene            2913..3491
                     /gene="hisB"
                     /locus_tag="KR294_003523"
     CDS             2913..3491
                     /gene="hisB"
                     /locus_tag="KR294_003523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazoleglycerol-phosphate dehydratase HisB"
                     /protein_id="HBH0241569.1"
                     /translation="MRIWKVERNTLETQILVELNIDGSGKAEIDTGIGFLDHMLTLMS
                     FHGKFDLKVICKGDTYVDDHHSVEDIGIAIGEAFKNALGDKKGIRRYSNIYIPMDESL
                     SMVAIDISNRPYLVFNAKFDTQMIGSMSTQCFKEFFRAFVNESRVTLHINLLYGENDH
                     HKIESIFKAFARALKEGSEIVSNEIASSKGVL"
     gene            3493..4098
                     /gene="hisH"
                     /locus_tag="KR294_003524"
     CDS             3493..4098
                     /gene="hisH"
                     /locus_tag="KR294_003524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisH"
                     /protein_id="HBH0241570.1"
                     /translation="MNIIVDYGLGNIDSVSRGFRKAGIETKISSDIDEIKQADSLILP
                     GVGAFRDSISALDKLGLIPIIKEHVSKGKFMIGICLGMQLLYEKSYEYGEYEGLGLIK
                     GSIDKLDISLKVPHMGWNNLKFNKANDDILKYINEDDYVYFVHSYYANSSNEELIAFS
                     EYEKKIPAIVRKGNVYGIQFHPEKSGEVGLNILRAYGEMIK"
     gene            4095..4817
                     /gene="hisA"
                     /locus_tag="KR294_003525"
     CDS             4095..4817
                     /gene="hisA"
                     /locus_tag="KR294_003525"
                     /EC_number="5.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-(5-phosphoribosyl)-5-[(5-
                     phosphoribosylamino)methylideneamino]imidazole-4-
                     carboxamide isomerase"
                     /protein_id="HBH0241571.1"
                     /translation="MIIFPAIDIKDNKCVRLTQGEFDKVNVYYDNPLEVAYKWKNEGA
                     EYIHIVDLNGARSEFGVNTKIIEDIANNIDIPIQVGGGVRDKEKVKSLINAGVTRVIL
                     GSIAIENLNLVEELVNEYKEKIVVSIDAKDGKVAVRGWEVVSNVDSLTLCKQLEKIGV
                     QTIVYTDISKDGMLQGPNFDIYERIAKETSLNVIASGGVTSIEDVKRLKAMNLYGAII
                     GKALYDKKIDFKEAQQLCLLGE"
     gene            4799..5557
                     /gene="hisF"
                     /locus_tag="KR294_003526"
     CDS             4799..5557
                     /gene="hisF"
                     /locus_tag="KR294_003526"
                     /EC_number="4.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000880088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisF"
                     /protein_id="HBH0241572.1"
                     /translation="MLTRRIIPCLDVRNGRVVKGKKFKDIVDVDSPEVLGKFYSDCGA
                     DELVFYDITASNEERKTSLEFVTKVAENINIPFCVGGGVNKLEDFTDILRKGADKVSI
                     NSSAVKNPELIREASLKFGAQCVVLSIDAKKNEEGSWSVYVKGGREKTNLDAIEWAVK
                     GVELGAGEIVVNSMDEDGMKNGYDIELLSKITSLVNVPVIASGGAGKKEDFYEAVNKS
                     NVDGILAASVFHFGEIKINDLKKYLKDMGVEVRL"
     gene            5585..6253
                     /locus_tag="KR294_003527"
     CDS             5585..6253
                     /locus_tag="KR294_003527"
                     /EC_number="3.5.4.19"
                     /EC_number="3.6.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphoribosyl-AMP
                     cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE"
                     /protein_id="HBH0241573.1"
                     /translation="MDNKCNNVYSDEVEKFIRSIKFDDKGLVPVVVQEVVSKDVLMLA
                     YMNKDAIKKTLKDKVACYFSRSRQELWVKGETSGNTQKVVKMSYDCDVDTILLFVEQT
                     GVACHTGNYSCFYRDLFDDSSKMELEVQTNILKELYDLINERKNNPVEGSYTNYLFEK
                     GIDKILKKVGEESSEVIIASKNTDKSELIYEISDLVYHTLVLMIEKGVEIDEIKKELL
                     KRRK"
BASE COUNT         2633 a          544 c         1254 g         2008 t
ORIGIN      
        1 tatagtaaaa ttaaatacaa aattaaatca tcaccatcat catagattaa agggattgta
       61 atatgaaatt aattcataga cacaagccct gtttttagtg taattggtct tgtatctatg
      121 atgggaagta attttaagag aaaattatag ccatataggt ataaagccta tgtggctttt
      181 ttattgtttt aaatttgcaa atataagagt aaatttaatg aagagggtga gaatgtgaaa
      241 tttttgagga ttgaagatga ggttatttat tctaaaaaaa gatataaatt aaaaagggaa
      301 atagataaac tttttttgga tgaagaatat tttcaaatag aaccacaatt atttgaagaa
      361 tatgatgaat ttacaactat aaataataaa attccagaag aatctatggt aaaggttgta
      421 aatggaaaag taatggtact tagagctgat ataactacaa gtataataaa aagccttgta
      481 ccaagatggg aagatggttt aaagcttaag cttttttata attcatcaat atataaaaat
      541 aaaaatacag ttggaataaa agagataaga caaataggtt gtgagtatct aggagaagcc
      601 tctgtagaag cagatagaga agtagtgaaa ttagctctta agatacttga aaaatacaat
      661 aataatttta ttctagaggt tgggagtagc aagtatattc atggtttgtt agaagaatta
      721 aatttaaata agaattgtga aaatcaaatt aaaaatttac tatatacgaa gaacactcat
      781 gaactaaaag tatatattga agaattaaaa attaagcgtg aagtaaaaga gttattatca
      841 aatattttaa gtttacaagg gaatttatat aatgttattg aaaaatcaaa caagttctat
      901 tgtaataata agatgaagca agctcttgaa gaattaaagc aagtaaataa cttgattgag
      961 gaatgtaatt ttttagataa ggctagattt gatttatcaa tgattactat gcttgactat
     1021 tatgaaggaa ttatgtttag aggatactac ccaaactcat ataaagaaat tcttagtggt
     1081 ggaagatatg attctttaac taaagagtat ggaaaagaaa ttccagccat tggatttaca
     1141 ctaagtgttg atgagttaat gaagtatgta tataagtaaa gtttagaagg agggattgct
     1201 ttggattatt tgactatagc actagcaaaa ggacgaattg aaggggaatc atttaaaaaa
     1261 tttaaaaaaa tgggtctagg agacagtata gacacagata cgagaaaact aatttttaaa
     1321 gatgaagaaa ataaaattat atatatacat gtaaagccat cagatgtagt tacatatgtt
     1381 gaaaaaggag tcgctgacct cggtatagca ggtaaagata ctattttaga gaatgagaca
     1441 gatgtatatg aaatatatga tttaggtttt ggaaaatgta aatttgctgt agcaggatta
     1501 aagggagata gcatatatag agaagatgaa tatttaaaag tggcaacaaa gtatcccaat
     1561 atagcaaaaa agtattttaa agagaaaggt caaaaaattg aaataataaa attaaatggt
     1621 tctgtagaac tagctccaat agtagggttg tcagatgtaa ttgtagatat agttgagact
     1681 ggcaatacac ttaaagcaaa tggtcttgaa atattagaag acatatgtaa tataagtgct
     1741 agaattatat caaatagagc tagctataga tttaaatatg aacaaattca gaatataatt
     1801 cgtttatttg aagaacttga taattaaaat ataattgagc tttataagga gggatttaag
     1861 ttgagagaaa aagaaagcat aagagagtta aagggatatg aaccaaatca cgtaaactgt
     1921 aaagtaaaac ttgatgcaaa tgaaggaagt aagaggttgt ttaaatacct tattaaagaa
     1981 atttcagata gtgatataga tttaaattta tatcctgaag attcttatag tgatttgaaa
     2041 gaatctataa tagattacat aaatatttct ggagtaaata agaaaaatct tctagtagga
     2101 aacggttcaa gtgaaataat tgatttaata atacatactt ttgtagataa agatgaagta
     2161 atattgagtt tctctccaag ttttagtatg tattctatat atagtcagat aaatgggtct
     2221 aaatttatag gtgttgaaag tgatgaaaat ttagttataa atatagataa tgtgattgaa
     2281 aaagtaaagg agaataatcc taaaatagta attgtatgta atcctaataa tccaactgga
     2341 acaatattaa agagggaaga gataataaag cttttagatt caactaatag tctagtggtt
     2401 ttagatgaag catatatgga ttttggagaa gaaagcatgt taagtgatgt ttttaagtat
     2461 gataatctaa tagttcttag aactttatca aaggcatttg gattggctgg aataagaaca
     2521 ggatatatgt tatctaatag tagtttaata aattctgttg agaaagtaag acctccatat
     2581 aatttaaatt cattatcaga ctttattgct acaagagcac ttagaaataa agatgtggta
     2641 aaggcttata taaaggaagt aaaagaggaa agagaagttt tatataaaga aatgattggt
     2701 atgggaatta aagcatataa atcacaagca aattttatat tattttattc tgaaatcgaa
     2761 aatttatcac aaaaacttat tgatagaggt gttttaataa gaaaatttgg tggaaagtta
     2821 gaaaattatt acagagttac aattggtgat aaagaagaaa attctatgtt tgttggagct
     2881 ataagagata ttttgaaaaa ggagaaatag gtatgagaat ttggaaggta gaaagaaata
     2941 ctcttgaaac acagatttta gtagaattaa atattgatgg ttctggtaaa gctgaaatag
     3001 atactggaat aggattttta gaccatatgc ttaccttaat gtcatttcat ggcaagttcg
     3061 atttaaaagt gatttgtaag ggtgatacat atgtagatga ccaccatagt gtagaagata
     3121 taggtatagc tataggtgaa gcatttaaaa atgctctagg tgacaaaaaa ggaatacgaa
     3181 gatattctaa tatctatata cctatggatg aatctctatc aatggtagca atagatataa
     3241 gcaatagacc ttatcttgta tttaatgcta aatttgatac ccaaatgatt ggtagtatga
     3301 gtactcaatg ctttaaagaa ttttttagag cttttgtaaa tgaatcgaga gtaacattac
     3361 atatcaatct cttatatggg gaaaatgacc atcataagat agaaagtatt tttaaagcat
     3421 ttgcaagagc tttaaaagag ggtagtgaaa tagtttctaa tgagatagca tcttcaaagg
     3481 gggttttgta gaatgaatat aatagtagac tatggtcttg gaaatataga ttctgtgtct
     3541 aggggtttta gaaaagctgg aatagaaact aaaatttcta gtgatataga tgaaataaaa
     3601 caggcagatt cacttatact tccaggtgtt ggagctttta gagattctat aagtgcctta
     3661 gataaactag gattgatacc aataataaag gagcatgttt ctaagggtaa atttatgata
     3721 ggtatatgtc taggaatgca attactttat gaaaaaagtt atgagtatgg agaatatgaa
     3781 ggattaggac ttataaaagg aagtattgat aaactggata taagtttaaa agtgccacat
     3841 atgggatgga ataatctaaa atttaataag gcaaatgatg atatacttaa atatataaat
     3901 gaagatgatt atgtatactt cgttcactca tattatgcaa attcatcaaa tgaagaacta
     3961 attgcatttt cagaatatga aaagaaaatc cctgctattg ttagaaaagg caatgtatat
     4021 ggtatacaat ttcatcctga aaaaagtgga gaagtagggt taaatatatt aagagcatat
     4081 ggggagatga taaaatgata atatttccag caatagatat aaaagataat aagtgtgtaa
     4141 gacttacaca aggagaattt gacaaagtaa atgtatatta tgataatcca ttagaagtag
     4201 catataaatg gaaaaatgaa ggagcagaat atatacatat agtagattta aatggtgcta
     4261 gaagtgaatt tggtgtaaat acaaaaataa ttgaggacat agcaaacaat atagatatac
     4321 ctattcaagt tggcggtgga gttagggata aggaaaaagt caaaagttta ataaatgctg
     4381 gtgttactag agtaatatta ggtagtatag cgattgaaaa tttgaattta gttgaagaat
     4441 tggtcaatga atataaagag aaaattgtag tttctataga tgctaaagat ggaaaagtag
     4501 cagttagggg atgggaagtt gtaagcaatg tagactcatt aacattatgc aaacaacttg
     4561 aaaagatagg tgtacaaact attgtttata cagatatatc aaaagatggg atgttgcaag
     4621 gtccaaattt tgacatatat gaaagaatag caaaggaaac atcactaaat gttattgctt
     4681 ctggaggcgt aacttctata gaagacgtaa aaagactaaa agctatgaac ttatatggtg
     4741 caataatagg taaagcgctt tatgataaaa agatagactt taaggaggca caacaattat
     4801 gcttactagg agaataatac cttgtctaga tgtgagaaat ggaagagtcg taaagggaaa
     4861 aaaatttaaa gatatagtag atgttgatag tccagaagta cttggaaaat tttatagtga
     4921 ttgtggtgca gatgaacttg tattctatga tataactgca tcaaatgaag agagaaagac
     4981 atctttagaa tttgtgacaa aagttgcaga aaatataaat ataccatttt gtgttggtgg
     5041 aggagtaaat aaattagaag atttcactga tattttaaga aaaggtgctg ataaagtttc
     5101 tataaattca tcagcagtca aaaatcctga attaataagg gaagcttcat taaaatttgg
     5161 agcacaatgt gttgttttat cgatagatgc aaagaaaaat gaagagggtt catggagcgt
     5221 atacgtaaaa ggtggaagag aaaaaactaa tctggatgca attgaatggg ctgttaaagg
     5281 tgtagaactt ggagcaggag aaatcgttgt aaatagtatg gatgaagatg gaatgaaaaa
     5341 tggatatgat atagaattat tatcaaagat aacttcttta gtaaatgtac ctgtcatagc
     5401 atctggaggc gctggaaaaa aggaagattt ttatgaggcg gttaataaat ccaatgtaga
     5461 tggaatttta gcagcatctg tttttcattt tggcgagata aaaataaacg atttaaagaa
     5521 atatttaaaa gacatgggtg tagaagtaag attataagtt aaatactaaa aggagattag
     5581 aaatatggat aataagtgta acaatgtata cagtgatgaa gtagagaaat ttataagaag
     5641 tataaagttt gatgataaag ggttagtccc tgttgttgtt caagaggtag ttagcaaaga
     5701 tgtactgatg ttagcatata tgaataaaga tgctataaag aaaaccttaa aagataaagt
     5761 agcttgctat tttagtagaa gtagacaaga actttgggtt aaaggtgaga catctggtaa
     5821 tactcaaaaa gtagttaaga tgtcttatga ttgtgatgta gatactatac tactttttgt
     5881 tgaacaaact ggtgtagctt gtcatacagg caattattct tgtttttaca gagacttgtt
     5941 tgatgatagt tcaaaaatgg agcttgaagt acaaacaaat atattgaaag aattatatga
     6001 tttaatcaat gaaagaaaaa ataatccagt tgaaggttct tatactaatt atctttttga
     6061 aaaaggaata gataagattc ttaaaaaagt aggtgaagag agtagtgagg taattatagc
     6121 atcaaaaaat accgataaaa gtgaacttat ttacgaaatt agcgatttag tatatcatac
     6181 attggtttta atgatagaaa aaggtgttga aattgatgaa ataaaaaaag aattacttaa
     6241 aagaagaaaa tagaataaga tagattaatg ggtaataaga aaatatacca cttttaataa
     6301 aaagtggtat attttttatt ttatattttg atttatagaa taatatttaa attacttgat
     6361 aaaattaact atatatataa tttattgata aaataattct agtacattat ttattttaga
     6421 aaaaagataa ttatctaat
//
LOCUS       DAEPKC010000152         6315 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.154, whole genome shotgun sequence.
ACCESSION   DAEPKC010000152 DAEPKC010000000
VERSION     DAEPKC010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6315)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6315)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6315
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.154"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..647
                     /locus_tag="KR294_003528"
     CDS             <1..647
                     /locus_tag="KR294_003528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HBH0241574.1"
                     /translation="FISSILQGLLSILFNFTGDFGISIVLITLIVKLVLMPLSLKQRF
                     SVKKQQELAEKMEYIKEKYKNDTKELEKQIQVSSVESMKSMLGCLIVLVQMPVVYALY
                     HVCLDMTKEFTTIIIPWIANLGTFDNLFILPCIYTLIMLASNLVNYIPYLKINSQVKF
                     NKQMAVVTTITSLILTVRTPVAIGLYFITSAIYSLIEDICFRIYFNRKNRIVTK"
     gene            850..1521
                     /locus_tag="KR294_003529"
     CDS             850..1521
                     /locus_tag="KR294_003529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0241575.1"
                     /translation="MAKILVVEDEKRMQNIIVEYMQKGGYTCITADDGVEALTILKSN
                     NIDLMILDIMMPYLDGFSVCRVSREMTNIPIIILTAKGEEEDKLKGYEYGADDYITKP
                     FSPKVLLAKVNALLRRYTTDIPKNSLSLGKIFIMVASRQVYVEDKLIDLTYKEFELLR
                     LFMENPNQVFSREKLLNCIWGYDFEGNTRTVDTHIKTLRKKLGSEGHHIVTLIRSGYK
                     FEVKE"
     gene            1518..2648
                     /locus_tag="KR294_003530"
     CDS             1518..2648
                     /locus_tag="KR294_003530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH0241576.1"
                     /translation="MNSLRKIIEKLKNVDISNWIKQNFGLYSVRKKVFLLSKLSGALI
                     ILFYLVVEEFSINSKFEFWIWFIILVIFIMSIDFLLGKFISEPITSINKSAKSMSQLD
                     FSNPCTVNTNDEFGELSRSLNTMSTNLQQALSDLESANIQLEKDVNKERMLLEQRKEL
                     VDTISHEMKTPLGIIRAYTEGLIDEVDEEKKKNYMNVIIEETDRMNNMIVSLLDLSAL
                     EAGVSKLNPERFDFIEFVETVAGRLLIDIPDANFYFTYDLPEYEVFVVADKMRMEQVV
                     ENLVINAKKHVVYNGNLDLSITCENGLLLFEIYNDGRFIEQDEISKIWSKFYRSVQSQ
                     RTGGSGLGLAIVSQILTMQGLEYGVNNRDRGVEFYFMIPIDE"
     gene            3079..3924
                     /locus_tag="KR294_003531"
     CDS             3079..3924
                     /locus_tag="KR294_003531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0241577.1"
                     /translation="MIKVRELKFSYGKDKQILHGLNFEVKEGEIFGFLGPNGSGKSTT
                     QKILNGVLKGYNGHVSIFGKEVKAYTESLYQKIGVLFEFPYLYTNLSAIDNLEYFSSF
                     YPKNQRRDIYELLDLLEFKKEFINKPVSSYSKGMKQRISMARALVSNPKLLFLDEPTS
                     GLDPSGAVLFRKIIEEERKKGTTIFLTTHNMLDADLMCNNVAFIADGKIMVIDKPKNL
                     KMKNSNNKVEVEFVYNGNRDIEIVDIQELESGITFKYDEILSVHSKEPTLEEVFIKYT
                     GRMLV"
     gene            3924..4952
                     /locus_tag="KR294_003532"
     CDS             3924..4952
                     /locus_tag="KR294_003532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0241578.1"
                     /translation="MYSKFFTLVKKDFWMMIYGKFFVLTLGSLILYSCYINFGYVKFM
                     DEDSYHNNVYLYNPENISMSASPLINQVSSIGELKAKLDEDTSAVCIDMSSSKPKVIL
                     HESIKGVDNYRADYALSLLSSEKDHNSKISDNNAIIQINDKDTSEIKQRKDMTCEILF
                     FEIVAIGFLGIASLLFKEKQMGVMRITGILPVKRSLFILSKIFAFFICDLCFTVLLVV
                     FNIGFLEGIKILPQVLVQASILSIIMSLIGIGCSMLLRDFKQFSLIYLVVAVFITTPI
                     FLSANTSFEIDWIKYHPFYHVYSQLKNAFFMNFSKELVYFVVCSLTIIVLFLLVKYIF
                     NKELVREG"
     gene            4955..5968
                     /locus_tag="KR294_003533"
     CDS             4955..5968
                     /locus_tag="KR294_003533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0241579.1"
                     /translation="MIGLRYQLKSIKKDKMCIISFFLPVVMAILINFMGTIDISSLGE
                     IRFGIVKDTLPVQTEQWLKKYGMVSVYDTKMHLIREIKDIKTDTIGVVRDGKGIKTVF
                     YGNEINAIKNVGKTLPEMFRLKGDLKDVEVTILPKDSILKEFQNVFIAMILITAMFMG
                     CTFNAMNIISEKEDGISFINEVLPQSRSQYIIQKVFLGLLCGCLSSMITVFICLDISI
                     LDMIMMLLLVVFSAFISSLIGLFIGKLSEGLMVGIVYIKIVMILFIGTPLLIYLLGVN
                     TSGIGNLCYIMPSVATFNGIMEIINGNVIIIKDIVILAVHCVVWFMIYIILDKKRKLS
                     FSR"
BASE COUNT         2367 a          622 c         1084 g         2242 t
ORIGIN      
        1 atttcatttc aagtatattg caaggattat taagtatatt atttaatttt acaggtgatt
       61 ttggaatttc tattgtactt ataactttaa tagttaaatt agtacttatg ccactatcat
      121 taaaacaaag attttctgta aaaaaacagc aagaattagc tgaaaaaatg gaatatataa
      181 aagaaaagta taagaatgat actaaagaat tggaaaagca aatacaagta agttctgtag
      241 aaagtatgaa gagtatgctg ggatgtctta tagttttggt tcaaatgcca gtagtatatg
      301 ctttatatca tgtatgttta gatatgacaa aggaatttac aacaattata attccatgga
      361 ttgctaattt aggtacattt gataatttgt ttatattacc ttgtatatat acattaatta
      421 tgttagcttc aaatttagtg aattatatac catatttaaa aataaattct caagtaaagt
      481 ttaacaaaca aatggctgtg gtgactacca taacaagtct tatactaact gttagaactc
      541 cagtagccat aggtctgtac tttataacaa gtgcaattta ttcattaatt gaagatattt
      601 gctttagaat atattttaat cgaaaaaata gaatagtgac aaaataatat aattattatt
      661 agaaatattt tagcctgcta acatagaaaa agttagtagg ctatttttat ctatgatatc
      721 aattccatta agaatagtct aaaaaatact atcaaaatgc tataaaaaat actataaaaa
      781 aatagttgaa aaataaataa attaatataa actaaaataa agcctacaaa aaagaggtga
      841 taaatagaaa tggctaaaat actagttgta gaagatgaaa aaagaatgca aaatattatt
      901 gtagaatata tgcaaaaggg aggatatact tgtataactg ctgatgatgg agtcgaggca
      961 cttacaatat taaagagcaa caatatagat ttaatgatat tggatattat gatgccgtat
     1021 ttagatggat tttcagtgtg tagagtttca cgtgaaatga ctaatatacc tattattata
     1081 ttgacagcta aaggtgaaga ggaggataaa ttaaagggtt atgaatatgg cgcagatgat
     1141 tatataacaa aaccatttag cccaaaagta cttttagcaa aagttaatgc tttgttacgt
     1201 agatacacta ctgatattcc caaaaattca ttgagtttag gaaagatttt tattatggta
     1261 gcatcaagac aagtgtatgt agaagataaa ttgattgatt taacatataa agaatttgaa
     1321 ttattgcgtt tatttatgga aaaccctaat caagtttttt ccagagagaa acttttaaat
     1381 tgtatatggg gatatgattt tgaaggaaac acacgaactg tagatacaca tataaaaacc
     1441 ttacgcaaaa agcttggtag tgaaggacac catatagtta cattaattcg ttcaggatat
     1501 aagtttgagg ttaaggaatg aatagtttaa gaaagattat agaaaaactg aaaaatgtag
     1561 atatttcaaa ttggattaaa caaaattttg gactatattc agttagaaaa aaagtgtttt
     1621 tactttctaa attatcagga gcgttaatta tattatttta tctggttgtt gaagaatttt
     1681 cgataaactc taaatttgaa ttttggattt ggtttataat actggttata tttattatga
     1741 gtattgattt cttattggga aaatttattt cagaaccaat cacatctata aataaatctg
     1801 caaaaagtat gtcccaactt gatttttcta atccatgtac tgtaaatact aatgatgaat
     1861 ttggagaact ttctaggagc ctgaatacaa tgtctacaaa tctacaacag gcattatcag
     1921 acctagaaag tgcaaatatt caacttgaaa aggatgtaaa taaggaaaga atgctattgg
     1981 aacaaagaaa ggagttggta gatacaattt cacatgaaat gaagactcca cttggcatta
     2041 tacgtgcgta tacagagggg cttatagatg aagttgatga agaaaaaaag aaaaattata
     2101 tgaatgttat aatagaagaa actgatagaa tgaacaatat gattgtatca ttattagact
     2161 tatctgcatt ggaagcagga gtttctaaac ttaacccaga gcgttttgat tttatagagt
     2221 ttgttgaaac tgtggcaggt cgtcttttaa ttgatatacc agatgccaat ttttatttta
     2281 catatgattt gccagagtat gaagtttttg tagtggcaga taaaatgaga atggaacaag
     2341 tagtagagaa tctagttatt aatgcaaaga agcatgttgt atataatggt aatttagatt
     2401 tatcgattac atgtgaaaat ggcttgcttt tatttgaaat ttataatgat ggtaggttta
     2461 tagagcaaga tgagatttca aagatttggt ctaagtttta tcgtagtgtt caatctcagc
     2521 gtacaggagg ttcaggtcta gggcttgcaa ttgtttcaca aatacttaca atgcaagggt
     2581 tagaatatgg agtgaataat cgtgatagag gagtagagtt ttattttatg attccaattg
     2641 atgaataatt tagtattaat ttataaatta taagtatctg atgtaaaata tttttatttg
     2701 tatacgtaag tatttaaaga gaataaaata aaaaaactta atgaaaaagc ttaatgaaaa
     2761 agtctaataa aaagcttaat gaaaagctta ataaaaagtc ttgttttcct gatgaaaaca
     2821 agatttttta ttaagctttt tattatttca cttcgatttc acaagagaga cactctgatt
     2881 tcaccaaata gaaataaaat aggttaaata aattaaaaaa tagaagcgta attaaataag
     2941 gttacaaggg ggagtactta tgaaatggta tacatggttg actattatat tgataatatt
     3001 gctttctatt ccgcttaaaa ttaaatttat aaaatggtgg gatagacgac aaaaaaatga
     3061 taaaggaggt tatgatagat gataaaagta agagagttaa aattttctta tggaaaagat
     3121 aaacagatat tgcatggact taattttgaa gtaaaagaag gagaaatctt tggattcctt
     3181 ggacctaatg gttcaggaaa atccacaaca cagaaaatct taaatggtgt tttaaaaggt
     3241 tacaatggtc acgtatccat ttttggtaag gaagttaaag catacacaga atctttatat
     3301 caaaagattg gtgttttatt tgaatttcct tatttatata ccaatttaag tgcaattgat
     3361 aatttagaat atttttcgtc tttttatcct aaaaatcaaa ggagagacat atatgaactc
     3421 ttagatttgt tagagtttaa gaaagagttt ataaataagc ctgtatcatc ctactcaaaa
     3481 ggtatgaagc aacgtattag catggcaaga gcattggtaa gtaatccaaa gttgttattt
     3541 ttagatgagc ctactagtgg acttgaccca tctggagctg tactatttcg taagattatt
     3601 gaagaagaac gaaaaaaagg aacaactatc tttttgacta ctcataatat gctagatgca
     3661 gatttaatgt gtaacaatgt ggcttttatt gcagatggaa agattatggt aatagataaa
     3721 cccaaaaatt taaaaatgaa aaatagcaat aataaagttg aagtggaatt tgtatataat
     3781 ggaaatcgag atattgaaat tgtagatata caagagttag aatctggaat aacttttaaa
     3841 tatgatgaaa tcttaagtgt acattcaaaa gaacctacac tagaagaagt ttttattaaa
     3901 tacacaggaa ggatgttagt gtaatgtatt ctaaattttt taccttagta aaaaaagatt
     3961 tttggatgat gatttatggt aaattttttg tgctgacact tggctctctc atactttatt
     4021 cgtgttatat taattttggt tatgtaaagt ttatggatga agatagttat cacaataatg
     4081 tatatctata taatccagag aatataagca tgagtgcatc tccattaatt aatcaagttt
     4141 cttctatagg tgaattaaaa gcaaaacttg atgaagatac aagtgcagtt tgtattgata
     4201 tgagttccag taagccgaaa gtaattttac atgaaagtat taaaggagtt gacaattata
     4261 gagctgacta tgcattgtca ttattatcat cagaaaaaga ccataatagc aaaatatcag
     4321 acaacaatgc aataattcaa attaatgata aggatacatc tgagataaaa caaagaaaag
     4381 acatgacttg tgagatttta ttctttgaaa ttgtagctat tggattttta gggattgcct
     4441 ctttattatt taaagaaaag cagatgggag taatgcgtat tactggtatt ttacctgtaa
     4501 aaagaagtct ttttatatta tcaaagatat ttgctttttt tatatgtgac ctatgtttta
     4561 cagttctttt agtagtattt aatattggat ttttagaagg aataaaaata cttccacaag
     4621 tattagttca agctagtatt ttatcaatta ttatgtcttt gattggaata ggatgctcaa
     4681 tgttattgag agattttaag caattttctc ttatatatct tgtggttgct gtattcataa
     4741 ctacacctat atttctatct gcaaatacat cttttgaaat agattggatt aaatatcatc
     4801 ccttctatca tgtttatagt cagcttaaaa atgcgttttt catgaatttt tcaaaagaat
     4861 tagtttattt tgtagtgtgt tctttgacaa taatagttct atttttactt gtaaaatata
     4921 tttttaataa agaattggtt agggagggat aatcttgata ggattacgtt accagttaaa
     4981 gagtataaaa aaagataaaa tgtgtataat ttccttcttt ttaccagttg ttatggcgat
     5041 tttaataaat tttatgggaa caattgatat atcttcatta ggagagatac gttttggtat
     5101 agtgaaggat acacttcctg tacaaacaga gcagtggtta aagaagtatg gtatggtaag
     5161 tgtatatgac acaaaaatgc atttaatacg tgaaattaag gatattaaaa cggacacaat
     5221 tggagttgtt agagatggta aaggaataaa aactgtgttt tatggaaatg agattaatgc
     5281 tataaaaaat gttggaaaga cattgccaga gatgtttaga ctaaagggtg atttaaaaga
     5341 tgttgaggtt acaatattgc ctaaagatag tattttaaaa gagtttcaaa atgtttttat
     5401 tgctatgatt ttaattactg ctatgtttat gggatgcacc tttaatgcaa tgaatattat
     5461 atcggaaaaa gaagatggaa tatcatttat aaatgaagtt ttgccacaga gtagaagtca
     5521 gtatattata caaaaagtat ttttgggtct tttatgtggg tgtttatctt caatgataac
     5581 tgtatttata tgtttggata tttcaatatt agatatgata atgatgttgt tactcgttgt
     5641 attttcagca tttatttcat cacttatagg tttatttatt ggaaagttgt cagaaggtct
     5701 tatggtagga attgtttata ttaaaatagt aatgatttta tttataggta ctcctttgtt
     5761 aatatatctt ctaggggtta ataccagtgg tatagggaat ttatgctata taatgccttc
     5821 agttgctaca tttaatggta ttatggagat tattaatggt aatgtcatta ttatcaaaga
     5881 tattgtaatt ttggctgtac attgtgtagt atggtttatg atatatatta ttttagataa
     5941 aaaaagaaag ttatctttta gtagataact cagtataatt ataattggga caatttaata
     6001 ggtgatttaa tatactttgt atagtgtaat ttatgtagtg caatttgtat actttaattt
     6061 atgtagtgta atagttagtt ttattttata attattcaat ataatttagt aagaagttca
     6121 gtacaattag agctacttag tggaaaactt aataggtact taaactatat aaatacttta
     6181 ttttcctcca tttgtactat aaatttaatt tatgatataa atggaggtat tattatatga
     6241 tttgataaat ttcatcatta taacctacaa gtaaaggtat tattatataa agttaataaa
     6301 gatagtatca aaata
//
LOCUS       DAEPKC010000153         6086 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.155, whole genome shotgun sequence.
ACCESSION   DAEPKC010000153 DAEPKC010000000
VERSION     DAEPKC010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6086)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6086)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6086
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.155"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            64..1428
                     /locus_tag="KR294_003534"
     CDS             64..1428
                     /locus_tag="KR294_003534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase"
                     /protein_id="HBH0241580.1"
                     /translation="MDIKELVKMQRKYYNTGKTRDISFRIEQLKKLKLVVSQNEEKIL
                     LALKKDLNKSDFEGFMTEVGMFYSELNFAIKNIRKWSKIKRVKSSMVNFPSISKVVPQ
                     PYGVTLIMSPWNYPFQLALIPLVWSLVAGNCVILKPSEYSVSTSSVVKDIVEDTFSKE
                     YVAVVQGSQEESEKLLLERFDYIFFTGSTNVGKIIMKSASEHLTPITLELGGKSPCII
                     LKDANIDLTAKRLTWGKLINAGQTCVAPDYVLVHEDRKNELIEKIKYYTNKYFGDNPC
                     NNEQFPKIINQRHFNRILSLIDKDKIVYGGNYNKETLKIEPTIVDNVNWDDNIMKEEI
                     FGPIFPILTYKDLDEVIQKIIQMPNPLALYIFTKNKYLENKLLEMIPAGGCCINDTVT
                     HIATNYLPFGGIGESGMGSYHGKAGFDTFTHYKSVLKKLNLDVPIRYAPYDNKLIKVL
                     KKIM"
     gene            1567..2733
                     /locus_tag="KR294_003535"
     CDS             1567..2733
                     /locus_tag="KR294_003535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBH0241581.1"
                     /translation="MKINWNTKYTTIAIYTFIIAASSIIFYLVSSQIDVFSNNLDAIF
                     TTLQPFIIGFAIAYLLNFILKFYEDRIFIKSEKLKKLKQSSKRGLGLLLTYATATLIL
                     YLFMHFVLPQVIESIVGLANDIPMYVNNATKLIDKLMTDLNLDEQYFNLAVDKWNEFV
                     TYIIKFVTDLIPILGSMLKNVASSIWNIVLGLIVSVYLLIDKEKFYGLSKKITYAVFT
                     EKQAARILELTHRSNYTFGRFLGGKILDSFIIGILTFVILTLVKMPYTLLISVIIGIT
                     NIIPFFGPLFGAIPSTLIVMFVSPIKAFWLLLIILIIQQIDGNIIGPKILGDSIGISA
                     FWILFSLLVAGKLLGFIGMVIGVPMFAVIYSIIKDIVESKLDKKGLPTDTSDYM"
     gene            2850..3632
                     /locus_tag="KR294_003536"
     CDS             2850..3632
                     /locus_tag="KR294_003536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HBH0241582.1"
                     /translation="MAFIECKFKSKYTGGETDIIVILPVANGKELFSGKEIYDFEGKF
                     KTLYLFHGLEDDQSSWIRYTNVEHYAKNKNIALVIPRVETSFYTDMAYGHQYFTFVSE
                     ELPKFVRAIFPLSDKREDNFVAGMSMGGYGALKLALSKPKEFSAVASFSGSPDMIHEL
                     ENQQIETNADILFHDFGRPEDARNSENDLLYILKNLKERNEDIPKIYQFCGDRDFLYK
                     NNQMFKKYADSLGVDVEYEECVGGHEWRLWNLWIKKFIDIIG"
     gene            complement(3751..4404)
                     /locus_tag="KR294_003537"
     CDS             complement(3751..4404)
                     /locus_tag="KR294_003537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH0241583.1"
                     /translation="MSKSEKGKETKASIISAARELFFEQGYHKTTTRQIAERANINLG
                     LISYYFSSKSEIGAIIYEDIRNEMQSLIYNYHEEGTMMMFFLAMNADLCFLLKNEAYR
                     NFYLDIAYEEAILSYQRSVTEMVMKRYVNDKESIEHDELILSCIGILAMKPEIIRVYT
                     SHKYDISSQAVIKHFTKQFLINLGHSTDLCEEILEELSKYYIDIVDNFTPIITRVRT"
     gene            complement(4428..5792)
                     /locus_tag="KR294_003538"
     CDS             complement(4428..5792)
                     /locus_tag="KR294_003538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter family protein"
                     /protein_id="HBH0241584.1"
                     /translation="MLLLIVTCAIYIWIGFYFSKKVKTASDFLIAGRNLPLPILAATI
                     AATSFGGGCLVGGVQWGAERGLWVGMYSTIGAALACFINAFFAGKLRSLSCDITPADY
                     IETRYGHSVFLRAYQSLVTPISILAIMGSQLISFGSVSTAFGIPYDIAVIIGVIVIII
                     YTYTSGMWGVAVSAFIQLAICIVFLPIVAYISLKLVGDNPLLMLQSMVKEPFFPGNKS
                     ISDFMYTVLPLVLGSIFSYESFLRYQCADNAKNAVKSSVIAGFILLFLAFPIGIIGAI
                     GGSLFPNISSVQVLPQMISTTLPPLISVLFLAAILAAIMSTADSLMTSMSAIISRDIY
                     NKLLHPNIEFNDLKNTLKYSQIASALTAIIGAIIALKFDSLLELLFWPAPLCTGVIFA
                     PFVIGLCWKGATKKGAIYAVIVSVILALLNMIGILTVFDRILVPIIGGSITIFIVSKF
                     SKKD"
BASE COUNT         2297 a          761 c          918 g         2110 t
ORIGIN      
        1 gataaattta aatctttttc taaaaatgta ttaatataat tcttaaagaa aggattttta
       61 ataatggata taaaagagtt agttaaaatg caaagaaaat attataatac aggtaaaaca
      121 agagatatat cgtttcgtat agaacagttg aagaaactta agttagttgt atcacaaaat
      181 gaagaaaaaa tacttttagc actaaagaaa gatttaaata aatcggattt tgaaggtttt
      241 atgacagaag taggcatgtt ttatagtgaa ttaaactttg ctataaagaa tataagaaaa
      301 tggagcaaaa taaaaagagt taaatcaagt atggttaatt ttccatctat atccaaagtt
      361 gttccacaac cttatggtgt tactctcata atgtcacctt ggaattatcc atttcaatta
      421 gcacttatac cattagtttg gtcattagta gcagggaatt gtgttatatt aaaaccttct
      481 gaatattctg tgtcaacatc tagtgtagtt aaagacatag tggaagatac tttttcaaaa
      541 gaatatgttg cagttgttca aggaagtcaa gaagaaagtg aaaagttact attggaaaga
      601 tttgattata tattttttac aggaagtact aatgttggta aaataatcat gaaatcagca
      661 tcagagcatt taactcctat tactttagaa cttggaggaa aaagtccttg tatcatttta
      721 aaagatgcta atatagacct tactgccaaa agacttactt ggggaaaact aataaatgca
      781 ggacaaacct gcgtggctcc agattatgtt ttagtgcatg aagatagaaa aaatgagtta
      841 atagagaaaa taaaatatta tactaataag tattttggag ataatccatg taataatgag
      901 caatttccta aaatcataaa tcagagacat tttaatcgga tattatctct tattgataaa
      961 gataagatag tctatggtgg aaattataat aaggagacat taaagataga gccaactata
     1021 gtagacaatg ttaattggga tgataatata atgaaggaag aaatatttgg gcctatattt
     1081 cccattttaa catataaaga tttagatgaa gtaatacaaa aaattataca aatgccaaat
     1141 ccattggcac tttatatttt tacaaaaaat aagtacctag aaaataaact tttagaaatg
     1201 attccagcag gcggatgttg tatcaatgat acagttactc atatagctac gaattactta
     1261 ccttttggtg gtattggtga aagtggtatg ggctcatatc atggaaaagc tggattcgat
     1321 acatttactc actataagag tgtgttaaaa aaattaaatt tggatgtccc tattagatat
     1381 gctccatacg ataataaatt aattaaggtt cttaaaaaga taatgtaggt tatattgtag
     1441 aataataaat ataaataaaa ttgagtattt gtattctgaa tatattttat ttttaatttg
     1501 gtatatttgt tataaaagtg gtgattttgt gataaaattt aattatatag aaataaggag
     1561 gaaaaaatga aaattaattg gaatacaaaa tacacaacaa tagcaattta tacatttata
     1621 atagctgcta gtagtattat attttatcta gtatcatcac aaattgatgt attttctaat
     1681 aatttagatg ctatatttac aacattacaa ccttttataa taggatttgc tattgcatat
     1741 cttcttaatt ttattttaaa gttttatgaa gacagaattt ttataaaaag tgagaaatta
     1801 aaaaaactaa aacaaagttc aaaaagaggc ttgggtcttt tattaacata tgcaacagct
     1861 acattgatac tttacttatt tatgcatttc gtattgccac aagtaattga gagtattgtt
     1921 ggactagcaa atgatatacc tatgtatgta aacaatgcaa ctaagcttat tgataaatta
     1981 atgactgatt taaatcttga tgagcaatac tttaatttgg cagttgataa gtggaatgag
     2041 tttgttacat atattataaa gtttgtaaca gatttaatcc caatattagg aagtatgtta
     2101 aagaatgtag cctctagtat atggaatatt gtactaggat taattgtttc agtatactta
     2161 ttaattgata aagaaaaatt ctatggatta agcaaaaaaa taacttatgc agtatttaca
     2221 gaaaaacaag ctgccagaat tttagaatta actcatagaa gtaactatac atttggaaga
     2281 tttttaggtg gcaaaatatt agattcattc attataggta ttctaacatt tgtaatactt
     2341 acgttagtta aaatgccata tacattatta atatcagtta taattggtat tacaaatatt
     2401 atccctttct ttggaccttt atttggagct ataccatcta cgctaatagt gatgtttgta
     2461 tctcctataa aagctttctg gttattgttg attatattaa taatacaaca gatagatgga
     2521 aatattatag gacctaaaat acttggagat tcaattggta tatctgcatt ttggattttg
     2581 ttctccttat tggttgcagg aaaattatta ggttttattg gaatggttat aggagttcca
     2641 atgtttgcag taatttattc tataattaag gatattgttg aaagtaaatt ggataaaaag
     2701 ggattaccga cagatacttc cgattatatg tagctaaaaa atattatgta taattaaaaa
     2761 tatataaatt aagcaatatt taaagcactg agaaagttaa actcttggtg ctttttagat
     2821 ataaaattat tatagaagag gtgttttttg tggcatttat agaatgtaaa tttaaatcta
     2881 aatatactgg aggagaaact gatataattg taattttgcc tgtagcaaat ggaaaagaac
     2941 tttttagtgg taaagagata tatgattttg aaggtaaatt taaaacatta tacttatttc
     3001 atggtttaga agatgaccaa agctcatgga ttagatatac taatgtagag cattatgcta
     3061 aaaataaaaa tatagcccta gtaataccaa gagtagaaac tagtttttat accgatatgg
     3121 cgtatggaca ccaatatttt acttttgtaa gcgaggaatt acctaaattt gttagagcta
     3181 tatttccttt atcagataaa agggaagata actttgtagc tggtatgtct atggggggat
     3241 atggagcttt aaaattagcg ctttcaaaac caaaagagtt ttcggcagtt gcaagttttt
     3301 ctggttcgcc tgatatgatt catgagttag aaaatcaaca aatagaaacc aatgcagaca
     3361 ttctatttca cgattttggt agaccagaag acgctagaaa tagtgagaat gatttacttt
     3421 acatacttaa gaaccttaaa gaaagaaatg aagatattcc taaaatttat caattttgtg
     3481 gtgatagaga ttttttatat aaaaataatc agatgtttaa aaaatatgca gattctctgg
     3541 gtgtagatgt tgaatatgaa gagtgtgtag gggggcatga atggcgtctt tggaatttat
     3601 ggataaagaa atttatagat ataattggat agtacactta tggtattaac aggtatacta
     3661 taaaatatct ttaaatatga taaagactga aatcctaaaa tcaaattatg attttaaaat
     3721 ttcagtctct aagaatttaa taaaatttta ttaagttctt acacgagtta ttattggagt
     3781 aaaattgtca actatatcta tatagtattt actcaattcc tctaaaatct cttcgcataa
     3841 atccgtacta tgaccaagat taataagaaa ctgttttgta aaatgcttta ttacagcttg
     3901 agaagatata tcgtacttgt gtgaagtata aactctaatt atttcaggtt tcatagcaag
     3961 tataccaata caagaaagta ttaattcatc atgttctata gattctttat cattaacata
     4021 tcttttcatg accatttcgg ttacacttct ttgatagctt aaaatagctt cttcataagc
     4081 tatatccaaa taaaaatttc tatatgcttc gttttttaga aggaaacaaa ggtcagcatt
     4141 catagcaaga aagaacatca tcatagtacc ttcttcatgg tagttataga ttaaagactg
     4201 catttcattt cttatatctt catatattat agctcctatt tcgcttttac ttgagaagta
     4261 atagcttatt agacctaaat ttatattagc tctttctgca atttgcctag ttgttgtctt
     4321 atgataacct tgctcaaaaa ataattctct agcagcactt ataatactag cttttgtttc
     4381 tttgcccttt tctgattttg acatatttac tgtgtatacc tctcttttca atcttttttt
     4441 gaaaatttgc taactataaa tattgtaata gaaccaccta ttataggaac caaaattctg
     4501 tcaaatacag taagaatacc aatcatattt aataatgcca atataacact tactataaca
     4561 gcatagatag ctcctttttt tgtagcacct ttccagcaaa gaccaattac aaatggtgca
     4621 aatattacac ctgtacataa tggagctggc caaaacaata attctaataa actatcaaat
     4681 ttaagtgcta tgattgcacc tattatagct gtcaaagctg atgcaatttg agaatacttt
     4741 agagtatttt ttaaatcatt aaattctata ttaggatgta ataatttgtt ataaatatct
     4801 cttgatataa tagcactcat tgaggtcatt aatgaatcgg cagtagacat tatggcagcc
     4861 aatatagcag ctaagaataa tacagatatt aaaggtggca aagtagtcga tatcatttga
     4921 ggtaaaacct gaacagatga tatatttgga aataaactac caccaatagc tccaattatt
     4981 cctataggga aagcaagaaa taatagtata aatcctgcaa ttacactact tttaactgca
     5041 tttttagcat tatcagcaca ttgatatctt aaaaaacttt cataagaaaa tattgagcct
     5101 aaaactaatg gtaaaactgt atacataaaa tcactaatcg atttatttcc tggaaagaat
     5161 ggttctttta ccattgattg taacataagt aaagggttgt cgccaactaa ttttaagctt
     5221 atataagcta ctattggcaa aaacactata caaatagcaa gttgaataaa tgctgatact
     5281 gcaactcccc acattcctga tgtataagta tatataatga taactataac tcctataatt
     5341 acagctatat cataaggaat accaaatgca gtagatacag aaccaaaaga aatcaattga
     5401 ctacccataa tagctagtat agatattggt gttacaagac tttgataagc tcttaaaaat
     5461 acactatgac catatctagt ttcaatataa tcagcaggtg ttatatcaca agataagctt
     5521 cttaattttc ctgcgaaaaa tgcatttata aagcaagcta aagctgcacc tatagtagaa
     5581 tacattccaa cccaaagtcc tctttcagct ccccattgaa ctccaccaac taagcaccct
     5641 cctccaaaag atgtagcagc aatggttgca gctagtatag gcaaaggcag atttctacct
     5701 gcgattagga aatcggatgc tgttttaact ttttttgaaa aataaaaacc aatccatatg
     5761 tatattgcac acgtaacaat taaaagtaac atagtctttt ctcctttata aaatatttta
     5821 ataaaatata caaaatatat ttaaaatata ttttatataa aagtagtacg atatttgttt
     5881 tattggtttt agattaatat agctataata atttatgata ttagatggaa attacgtaaa
     5941 aatagaaaat tgaaaattct gaaatttttg tatattgata tttatctcat agattctttt
     6001 ttgtaattgt aacacgcttt tatttttaaa tcaatagtac atgtataaaa ataaaaggaa
     6061 tttaaataag aaaaagatat ttttaa
//
LOCUS       DAEPKC010000154         6057 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.156, whole genome shotgun sequence.
ACCESSION   DAEPKC010000154 DAEPKC010000000
VERSION     DAEPKC010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6057)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6057)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6057
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.156"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(<1..645)
                     /locus_tag="KR294_003539"
     CDS             complement(<1..645)
                     /locus_tag="KR294_003539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family ligand binding domain-containing
                     protein"
                     /protein_id="HBH0241585.1"
                     /translation="MKDKNTYFNRKGQENFIDIFLKDDIKKGANFKRHWHEHLQIYYF
                     IDGIAYLECGLDNFKVVPGNIVIANSNELHYLESLSDNLKFYSIRIEPTFLFSNQVDL
                     LQTKYLAPLALNHIVFNNLIQNDSLILKCITTILDEYHNKEVGYELSIKANIYQLIVL
                     LLRSHIDKIYSEDEFIKRKYSLEKFECIFDLIEEKYMDKITLKELASRVNLSAHH"
     gene            786..2213
                     /locus_tag="KR294_003540"
     CDS             786..2213
                     /locus_tag="KR294_003540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH0241586.1"
                     /translation="MTNSFKKDDNRKKITVLFVVIAMTFMATLDSSIINVALPVLASK
                     LNVSLASIEWVIASYSIIICSTLLFFGRLGDIIAKSRVFQVGTILFTSASLLCGLSNS
                     LTLLIVCRFIQGIGASAYMANNHGIITELFPKESRGKALGILVTAVAIGNMVGPSVGG
                     FILSIFNWNVIFFINIPIGLIVIFLNTKFLPNSKKSSENMDKTGAILQFLGTTLFFSA
                     LISAQQTGLLNPYILIALLLSIIFIILFLILEKKHPQPLLDLEIFRNFKFSLNLICAL
                     TSFICIASSSILIPFYLQSTMKLPPIQAGLFMILSPLILAIFSPIFGNISDKIKSEKI
                     ILIGLLVMSFGFFLMSRLKESSALILFVIYISIISIGQAIFQPANNALIMSSCSRSKL
                     GVVGSINSLVRNLGQVIGITISTTLLYNFMSIKAGYRVNDYVINNDKIFVFGMRNVYI
                     IVTLVCLIGAILIGFYLFKYNKNEQ"
     gene            complement(2409..5003)
                     /gene="clpB"
                     /locus_tag="KR294_003541"
     CDS             complement(2409..5003)
                     /gene="clpB"
                     /locus_tag="KR294_003541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HBH0241587.1"
                     /translation="MDVEKMTLRVQKSLNEAYNEAVKNHNQQVDVIHLFSALINQEDG
                     LIPNIIEKMNISIDSLRNTVNFEIDKLPKVYGEGADSQGVSATRKINEVLIKAESISK
                     EFKDSYISVEHVMLAMMETESKSAVGKILKQYNINKNDFLNILSQVRGSQRVETQDPE
                     GTYDALARYGTNLVDLAKKNKLDPVIGRDEEIRRIIRILSRRTKNNPVLIGEPGVGKT
                     AIVEGLAERIVRGDVPEGLKDKIVFSLDMGALIAGAKYRGEFEERLKAVLKEVQSSDG
                     KIILFIDEIHTIVGAGKTEGSMDAGNLIKPMLARGELNCIGATTFDEYRKYIEKDKAL
                     ERRFQPVIAEEPTVEDTISILRGLKERFEIHHGVRIHDNAIVAAAKLSHRYIQDRFLP
                     DKAIDLIDEAGAMIRSEIDSLPTELDVVRRKLFTLETEREALLKENDDKSKSRLDDIQ
                     KEIAELKSKNDEMTAKYEKEKSQILDIKNLKAQLDEAKGKAEKYEREYDFNKAAEVKY
                     GEIPKLEEQIKQYEENMNDGSENSLLKEEVTEEEISSIVSKWTGIPVTKLVEGEREKL
                     LKLEDELHKRVIGQDEAVTAVSNAVIRARAGLKDERKPIGSFIFLGPTGVGKTELAKT
                     LARNLFDSEDNIIRIDMSEYMEKHAVSRLVGPPPGYVGYEEGGQLTEAVRRAPYSVIL
                     FDEIEKAHEDVFNMFLQILDDGRLTDNKGKTVDFKNTLIIMTSNIGSNYLLEAGGNIT
                     ETTNNLVMNEMKHRFKPEFLNRVDDIIMFKPLDQENIKKIIDIFMKDLKNRLKEKDIT
                     IEVTNSAKDVMVREGYDPVYGARPLKRYIGNTLETIIAKKLIAGDVYNGCTIVIDGKD
                     ENIEVLVK"
     gene            complement(5040..5636)
                     /locus_tag="KR294_003542"
     CDS             complement(5040..5636)
                     /locus_tag="KR294_003542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241588.1"
                     /translation="MSLKLDRNVLQWFDYVFENEKTSLRHYNFNCTLKEISSTSLNKV
                     AFILEKNNSKYWKLYFEIPAEVTLKLKQNIHPLFREYIYEQISLYNNNQIYNFVNSNI
                     LKVFNNIAIYQYNILENLYTIDFKKSFIDKCQYLLIGEKRLIDEDLYLIAKSKEVFDF
                     FNSDGTFNLTLSFDIQKNENLLDSLLELRKSIIINERI"
     gene            complement(5653..6057)
                     /locus_tag="KR294_003543"
     CDS             complement(5653..6057)
                     /locus_tag="KR294_003543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication/maintenance protein RepL"
                     /protein_id="HBH0241589.1"
                     /translation="MDKTLKKDLNQEYTESKSLVMNKSKYMNVCFKNYIKVVEGMYTK
                     RDLIPLKLINSMDKNNKIRKTLYELSCEFEYPKTSLSSLFTELKKMDFLQRVKNGEYM
                     INPHIAYKGSRADKESLLAEYNQIKRPNKVSK"
BASE COUNT         1918 a          991 c          656 g         2492 t
ORIGIN      
        1 gtgatgtgca ctcaagttca cacgactagc aagttctttt aatgtaattt tatccatata
       61 tttttcttct atcaaatcaa agatacattc aaatttttct aaagaatact ttctttttat
      121 aaattcatct tcagaatata ttttatcaat atgacttctt aataagagta ctattaattg
      181 atagatatta gcttttatag ataactcata tccaacttct ttattgtgat attcatcaag
      241 tatagttgta atacatttta aaatcagaga atcattttga attaaattat taaatacaat
      301 atgatttaaa gccaatggtg ctaagtactt ggtttgtaac aaatcaactt gattactaaa
      361 aaggaatgtg ggttcaatac gaatactata gaattttaaa ttatctgata agctttctaa
      421 ataatgtaat tcattactgt ttgctattac aatatttcca ggcactacct taaaattatc
      481 caatccacat tcaagatatg ctataccatc aataaaataa tatatttgta gatgctcatg
      541 ccaatgtctt ttaaagtttg ctcctttttt aatgtcatcc tttaaaaaaa tatctataaa
      601 gttttcttga cctttcctgt taaaatatgt atttttatcc ttcattattc ccccctcatc
      661 aaaatagtgc taattataag caatatagtt attgtattca ttatttcata tcgctattat
      721 ataaaatgta actatcattg taaacattaa cataatgcag tcattataat aaggaggtaa
      781 taaaaatgac aaactctttt aaaaaagatg ataatagaaa aaaaatcaca gttttatttg
      841 tagtcattgc catgactttt atggcaacat tagattctag tattataaat gttgctctcc
      901 cagttcttgc aagcaaacta aatgtatctc tagcatctat tgaatgggta atagcaagtt
      961 actcaattat tatttgttca acactattat tttttggaag acttggagat attattgcta
     1021 aatcaagagt atttcaagta ggtactattc tctttacatc agcttcatta ctatgtggat
     1081 taagtaattc tttaacttta cttatagttt gccgctttat tcaaggaata ggcgcttctg
     1141 cctacatggc aaacaatcat ggaattatca cagaactatt tccaaaagaa agcagaggaa
     1201 aagccctagg gattttagtt actgcagttg ctattggaaa tatggttgga ccatctgtgg
     1261 gaggatttat tttgtcaata tttaattgga atgttatatt ttttataaat attccaatcg
     1321 gtcttattgt aatcttttta aatacaaaat ttcttcctaa tagtaaaaaa tcttcagaaa
     1381 atatggataa aactggtgct atacttcaat ttttaggaac aacattattt tttagtgctc
     1441 taattagtgc tcaacaaaca ggattactaa atccatatat attaattgca ctattattat
     1501 caattatttt tattatatta tttttgatat tagaaaaaaa acatcctcaa ccgcttcttg
     1561 accttgaaat ttttagaaat tttaaatttt cattgaattt aatttgtgct cttacatcat
     1621 tcatttgtat tgcatcatca agtattttaa ttccatttta tttacaaagt actatgaaac
     1681 ttccccctat tcaagcaggt ttatttatga tactatcacc tttgatttta gccatttttt
     1741 cacctatatt tgggaatata tcagataaaa ttaagtcaga aaaaattatt ttaattggtc
     1801 ttctcgttat gagttttgga ttctttctaa tgtcaagatt gaaagaaagt tctgccctta
     1861 ttttatttgt aatttatata tcgataatat caataggaca agctatattt caacctgcta
     1921 acaatgcttt gataatgtca agctgttcta gaagtaagct aggagttgta ggaagcataa
     1981 attcccttgt aagaaattta ggacaagtta taggtattac tatttctaca acacttttat
     2041 ataattttat gagtattaaa gctggatata gggtcaatga ttatgtgatt aataatgata
     2101 aaatatttgt atttggaatg agaaatgttt atattattgt tacacttgtt tgcttaatag
     2161 gtgcaatatt aattggcttt tatttattta aatataataa aaatgaacaa tagtttttat
     2221 aattatattc aaattatgat tatattataa gaaatttact aaaatacttc ctttgagtta
     2281 aatttaattt ggacatattg acttaaaaat gttttattaa tttgataaaa tatttctttt
     2341 cctatagttt ataaataaaa atcagctgag caaaatattt agtatattat gctcaactga
     2401 ttcttttatt atttaactaa aacttcaata ttttcatctt ttccatctat aactatagta
     2461 catccattat acacatctcc agcaataagt ttctttgcaa ttatagtttc taatgtattt
     2521 cctatatatc tcttaagagg tcttgctcca tatacagggt catatccttc tctcaccata
     2581 acatcttttg ctgaatttgt aacttcaata gtaatatctt tttcttttaa tctatttttt
     2641 aaatctttca taaatatatc tataattttc ttgatatttt cttggtctaa aggcttaaac
     2701 attataatat catctactct gtttaaaaac tcaggtttaa atctatgctt catttcattc
     2761 attactaaat tgttagtagt ctctgttata tttcctcctg cttctaatag ataattactt
     2821 cctatattag aagtcattat tataagagta tttttaaagt ctactgtctt acctttatta
     2881 tcagtaagtc taccatcatc taatatctgt aagaacatgt taaatacatc ctcatgtgct
     2941 ttttctatct catcaaatag tattacagaa taaggagcac gtctaactgc ttctgtaagt
     3001 tgaccaccct cttcatatcc cacgtaccct ggaggaggtc caactagtct tgatacagca
     3061 tgtttttcca tgtattcaga catatctatt cttattatat tatcttcact atcgaataaa
     3121 tttctagcaa gagtttttgc aagttcagtt ttaccaacac ctgtagggcc taagaaaata
     3181 aatgaaccaa ttggttttct ttcatctttt aatcctgctc ttgcacgtat tactgcattt
     3241 gaaactgctg taactgcttc atcttgtcca ataactcttt tatgaagttc atcttctagt
     3301 ttaagtaatt tttctctttc tccttcaact agtttagtta ctggtatacc tgtccacttt
     3361 gatacaatgc tagatatttc ttcttcagta acttcttctt ttaaaagaga attttcagaa
     3421 ccatcattca tattttcttc gtactgcttt atttgttctt ctaacttagg tatttcacca
     3481 tatttaacct ctgctgcttt gttgaaatca tattctcttt catacttttc agctttacct
     3541 ttagcttcgt ctaattgagc ctttaagttt ttaatatcta atatttgact cttttctttt
     3601 tcatattttg ctgtcatttc atcattttta gattttaact ctgctatttc tttttgaata
     3661 tcatccaatc ttgatttact tttatcatca ttttctttaa gtaatgcttc tctttcagtt
     3721 tctaatgtaa ataactttct tctaacaaca tctaattctg ttggcaatga atctatttca
     3781 ctacgaatca tagctccagc ttcatcaatt aaatcaattg ctttatctgg taaaaatcta
     3841 tcttgtatat atctatgaga aagttttgct gctgctacaa tagcattatc atgtattctt
     3901 actccatgat gtatttcaaa tctttctttt aaacctctaa gtatagatat tgtatcttca
     3961 acagtaggtt cttctgcaat tacaggctga aaacgtcttt caagagcctt atctttttct
     4021 atatactttc tatattcatc aaaagtagtt gcaccaatac agttcaattc acctcttgca
     4081 agcataggtt taataagatt acctgcatcc attgaacctt ctgttttacc agctccaaca
     4141 atagtatgaa tctcatctat aaacagtata atttttccat cagaactttg aacttctttt
     4201 aaaactgcct ttaatctttc ttcaaattca cctctatatt ttgcaccagc aattaaagct
     4261 cccatatcaa gtgagaatac aatcttatct tttaaacctt ctgggacatc tcctcttact
     4321 attctctctg ctaacccttc tacaattgca gttttaccta cacctggctc accaatcaat
     4381 acaggattat tttttgttct tcttgataaa attcttataa tccttcttat ttcttcatct
     4441 ctcccaatta cagggtctaa tttatttttc ttggctaaat ctactaagtt tgttccatat
     4501 ctagcaagtg catcatatgt gccttctggg tcttgtgttt ctactctttg actacctctc
     4561 acttgtgata aaatatttaa aaagtcattc ttatttatat tatattgttt taatatttta
     4621 ccaacagctg attttgattc tgtttccatc attgcaagca taacatgttc tacacttata
     4681 tatgaatctt taaattcttt agaaatactc tctgccttta taagcacctc atttattttt
     4741 ctagtagctg atactccttg tgagtcagca ccttctccat atacttttgg aagcttatca
     4801 atttcaaagt ttacagtatt tctcaaagaa tcaattgata tattcatttt ttcgattata
     4861 tttggtatca atccatcctc ttgattaata agtgctgaga aaagatgaat tacatctact
     4921 tgttggttat gattttttac tgcttcgtta taagcctcat ttaaactttt ttgaactctt
     4981 aaagtcattt tttctacgtc catataaatc cctccatttt aatattatat ccaaataaat
     5041 taaattctct catttataat tattgatttt ctaagctcta aaagactatc aagtaaattc
     5101 tcgttttttt gtatatcgaa actcaatgtt aaattaaatg ttccatctga attaaaaaaa
     5161 tcgaatactt cttttgattt tgctattaaa tacaagtctt catctataag tcttttttca
     5221 cctattaata aatactgaca tttatctata aaactctttt taaaatcaat agtgtataga
     5281 ttttctaaaa tattatattg ataaatagca atattattaa acacttttaa tatgtttgaa
     5341 tttacaaaat tgtaaatttg attattgtta tacagtgata tttgttcgta tatatattcc
     5401 ctaaataaag gatgaatgtt ttgcttaagt tttaaagtaa cttcagctgg tatttcaaaa
     5461 taaagcttcc agtacttaga gttatttttt tctaaaataa aagctacttt gttcaaactg
     5521 gtagaactaa tctcctttag tgtacaatta aaattatagt gtctcaaact agttttttca
     5581 ttctcaaata catagtcaaa ccactgtaga acatttctat caagttttaa actcatataa
     5641 aaaccttctt ccttatttac taaccttatt aggtcttttt atctgattat attctgctaa
     5701 taaactttct ttatcagctc tactaccttt atatgctata tgtggattta tcatatactc
     5761 accatttttc actctttgta aaaaatccat ttttttcagc tccgtaaaca atgaagataa
     5821 agaagttttt ggatattcaa attcacaaga taattcatat aatgtttttc taatcttatt
     5881 atttttatcc atagagttta ttaattttaa tggaattaaa tccctcttag tatacattcc
     5941 ttctactact ttaatataat tcttaaaaca aacattcata tacttacttt tattcataac
     6001 taaacttttg ctctctgtat attcctgatt taaatccttt tttaatgtct tatccaa
//
LOCUS       DAEPKC010000155         5592 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.158, whole genome shotgun sequence.
ACCESSION   DAEPKC010000155 DAEPKC010000000
VERSION     DAEPKC010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5592)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5592)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5592
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.158"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..832
                     /locus_tag="KR294_003544"
     CDS             <1..832
                     /locus_tag="KR294_003544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="GTP pyrophosphokinase"
                     /protein_id="HBH0241590.1"
                     /translation="YKNNTYLLADKFIKDMMDSIKNNLTMIDNQLLSIYKNFHSGKSF
                     NMKVSKKEIEKLFAKLVYDAFSEKMNKSIGFVVDFKKPCETILNYSFNKQDISDEVLG
                     NFMLDEFARLNEIVNKDIDFNEQIEFEREPTFDDKFCKDLGNHFRSRLNTEFPWNLFF
                     RILFEIEPYNNTKDFENFVEFIKENVLLEENREQLLCQFEEDSKLIIEDIYDCIFNSI
                     SEIDSVEILYNYNLEKINFTSSEIINCICREYECYGEYLEEKEKLMNTFKEKIIQIFE
                     "
     gene            857..1465
                     /locus_tag="KR294_003545"
     CDS             857..1465
                     /locus_tag="KR294_003545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor guanylyltransferase"
                     /protein_id="HBH0241591.1"
                     /translation="MRHFSNIYELSKIILEEAICIEKTGVILAGGRNSRMGRDKAFLE
                     LHDKLFIEIAIEAFKNFDELIIISNNEELYSKYDIKVYNDIVKDVGPIGGIYTALEYA
                     KYDIVTIACDMPYLNNQIVERIANKMNDKSVISVTNGKLQPLCSGYKKSIINKVSLCI
                     RENDLKLRSFIDKIDKSYIYFDEEDLFLNVNTVDEYEKLTKV"
     gene            1513..1884
                     /locus_tag="KR294_003546"
     CDS             1513..1884
                     /locus_tag="KR294_003546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HBH0241592.1"
                     /translation="MNLLKCDSWAVILNNSDKESKAYKILDELKRNMYKVVAIDEEKK
                     PIEGIDVYECLKDVPHNIDVVAIIDKQSKMDVILEEVELLDIQNMWFEKGSFSEMMIK
                     KTKDLKLNIEYNLSLYDELTR"
     gene            2063..2401
                     /locus_tag="KR294_003547"
     CDS             2063..2401
                     /locus_tag="KR294_003547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HBH0241593.1"
                     /translation="MLIVTTEKVEGKKISKVLGLVRGSTIRAKHVGKDIGASFKNLVG
                     GELTGYNEMLTEARQIAIGRMVEDAEAKGANAVIAFRLSSASVMQGAAEMLAYGTAVV
                     LEDDNSILEK"
     gene            2867..3370
                     /locus_tag="KR294_003548"
     CDS             2867..3370
                     /locus_tag="KR294_003548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MogA/MoaB family molybdenum cofactor
                     biosynthesis protein"
                     /protein_id="HBH0241594.1"
                     /translation="MFNVAIITLSDKGYEGKREDITGKKLTEFVENTGAYKVTEYVLI
                     KDDKEMLKENIIRLCNSNKIDLILTNGGTGFSKRDITPEATKEVLEKEIPGLSEYMRM
                     KSTEITKKAILSRGVSGIRNNSIIINLPGSPKGAVENLSFIIDVLDHGIEVLRGEATE
                     CATKKSE"
     gene            3417..4376
                     /gene="moaA"
                     /locus_tag="KR294_003549"
     CDS             3417..4376
                     /gene="moaA"
                     /locus_tag="KR294_003549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP 3',8-cyclase MoaA"
                     /protein_id="HBH0241595.1"
                     /translation="MIDKYGRKIDYLRISLTDKCNLRCVYCMPPDVKFDKNYINENLS
                     FEDYKFIIKAMAEQGITKIRFTGGEPLLYPKLNELIKFTKEECGINNIGMTTNAIGLS
                     DRIFELEKCGLNKVNISLDSLKEYKYKSVTRGGNLKDVLKSIESCLNLGIKVKLNCVA
                     ISGFNDDELKDFMFLTVKSPIDVRFIELMPLGEANRVYKKGYFNVKEMIEKIYGLYKV
                     KNDEKSTAEYYMFKGAKGRIGIITPLSCSFCNTCNRIRLTSSGAIKLCLHSKEEIDIK
                     PFLHKPLLFRESMKDIIKQKPEKHHLIENKCSDTNRRMYEIGG"
     gene            4380..4850
                     /gene="moaC"
                     /locus_tag="KR294_003550"
     CDS             4380..4850
                     /gene="moaC"
                     /locus_tag="KR294_003550"
                     /EC_number="4.6.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic pyranopterin monophosphate synthase MoaC"
                     /protein_id="HBH0241596.1"
                     /translation="MLTHINEKGYAKMVDISEKDDTKRTAVATATITLSKEALEKVKN
                     GQIKKGDVLSVAQVAGIMGAKNTSSNIPMCHQIKLVGCDLEFDVDDSMSAIKIYATCK
                     SLGKTGVEMEALNACSLAALTIYDMCKAVDKKMVISNIHLVEKTGGKSGDFKFE"
     gene            4886..5317
                     /locus_tag="KR294_003551"
     CDS             4886..5317
                     /locus_tag="KR294_003551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MOSC domain-containing protein"
                     /protein_id="HBH0241597.1"
                     /translation="MAKVVSINISEKKGVIKVPVQCAELKINHGIVGDAHAGNWHRQI
                     SLLGKESIDKMKMKGFDQLKYGDFAENVTTEGIEVFSLPVGTKLRIGQCEVEVTQIGK
                     KCHNGCEIKKLTGDCVMPREGIFVKVLKEGIINVNDSIDVI"
BASE COUNT         2343 a          451 c         1017 g         1781 t
ORIGIN      
        1 ttataaaaac aatacatatt tacttgctga taaatttata aaggatatga tggactctat
       61 aaagaataat cttactatga tagataatca gcttttaagt atttataaaa actttcattc
      121 agggaagtct tttaatatga aagtaagtaa aaaagaaatt gaaaaattat ttgcgaaact
      181 agtctatgac gctttttctg aaaagatgaa taaaagtata ggttttgttg tagattttaa
      241 aaaaccatgt gagactatat tgaactattc ttttaataaa caagatataa gtgatgaagt
      301 tttaggtaat tttatgcttg atgagtttgc aagattaaat gaaattgtaa acaaggatat
      361 agattttaat gagcaaatag aatttgaaag agaaccaaca tttgatgata agttttgtaa
      421 agacctagga aatcatttta gaagtagatt aaacacagaa tttccatgga acctattttt
      481 tagaatatta tttgaaatag agccatataa caataccaaa gactttgaaa actttgtaga
      541 gtttataaaa gaaaatgtgc tactagaaga aaatagggag caattattat gccaatttga
      601 agaagatagc aaacttataa ttgaagatat atatgattgt atatttaata gtataagtga
      661 gattgatagt gttgaaattt tatataacta taatcttgaa aaaataaact ttacatcaag
      721 tgaaatcata aattgtatat gtagagaata tgagtgttat ggtgaatact tagaagaaaa
      781 agaaaagctt atgaatacat ttaaagaaaa gattattcaa atctttgagt aataggtcaa
      841 tgctgaagtg gcgctaatgc gccatttttc aaatatatat gaattaagta aaattatttt
      901 ggaggaggcg atttgtatag agaaaacagg tgtaattttg gcagggggaa gaaattctag
      961 aatgggtaga gataaagcct ttttagagtt acatgataag ctttttattg aaattgcaat
     1021 agaagcattt aaaaactttg atgagttgat aataatatct aataatgaag aattatattc
     1081 taaatacgat attaaagttt ataatgatat agtaaaagat gttggtccaa ttggaggaat
     1141 atatactgct cttgaatatg caaagtatga tatagttaca attgcatgtg atatgccata
     1201 tctaaataat caaatagtcg aaagaatagc taataaaatg aatgataaaa gtgtgatttc
     1261 agtgacaaat ggaaagttac aaccattgtg ttctggatat aaaaagagta taataaataa
     1321 agtatcttta tgtataaggg aaaatgattt aaagctcaga agctttatag ataaaataga
     1381 taaaagttat atatactttg atgaagaaga tttattttta aatgtaaaca ctgttgatga
     1441 gtatgaaaaa ttaactaaag tttaattagc tatggttgta aaatagagta ggatttatat
     1501 ggaggagagt ttatgaattt acttaaatgc gattcttggg cagtaatatt aaataatagc
     1561 gataaagaaa gtaaagcata taaaatatta gatgaactta aaaggaatat gtacaaagtt
     1621 gttgctatag atgaagagaa aaaacctatt gaaggaatag atgtgtatga atgtttaaaa
     1681 gatgttccac acaatattga tgttgtagct attattgata aacaatctaa gatggatgtg
     1741 attttagaag aagtagagct tttggatata caaaatatgt ggtttgaaaa aggaagcttt
     1801 agtgaaatga tgattaaaaa gactaaagat ttaaaattaa atatagaata taatttaagt
     1861 ttatatgatg agttgactag ataaaattat atatcttaat aataaaaata taattagtta
     1921 ataaaacata ttattttata gtatagattg gttaataaaa gtacagattg gttaatgaaa
     1981 cattaaatta caatatttgt taaaaaaatt gtgagttaca tgatataatg tattaaatag
     2041 gatactaagg agttgatata ttatgttaat agtaactaca gaaaaagtag aaggtaaaaa
     2101 gatatcaaag gttttaggat tagtgagagg aagtacaata agagcaaaac atgttggaaa
     2161 agatatagga gcaagtttta agaatcttgt tggaggagaa cttactggat ataatgaaat
     2221 gctcactgaa gcaagacaaa ttgccatagg tagaatggtt gaagatgcag aagctaaagg
     2281 tgcaaacgca gtaatagcat ttagactgtc ttcagcttca gttatgcaag gggcagcaga
     2341 aatgcttgct tatggaacag cagttgtttt agaagatgat aatagtattc ttgaaaaata
     2401 aaatataaat agttaaaaag aggcatcttt taaaaatttt atggatgcct ttttttattt
     2461 gaaaaaacta atttgagaag aaattttaac tattatgaca ataaaattag ggtgatatta
     2521 tataaataag taaaattata ttatataatg tatggtatag actttaaaaa ttttatttgt
     2581 agagaaaaat atggacaatg ttataataat tatagaaatt aaaagtactt acattcatta
     2641 tgtatgtgac atgtataatt agttttatat ttaatacagt tttgaagtaa tatcttcatt
     2701 ttgagaacgt tggaataata aaaaatgtat tattataggt gatataaata aaaaataaat
     2761 ataatatgtt atattgctga tagaaaagag aataaaagaa aataggtttt attaaaagag
     2821 atttttattt ataggactta atcaatgtat agaggggtga gaacatatgt ttaatgttgc
     2881 aattataaca cttagtgata aaggatatga aggaaaaaga gaagatataa caggaaaaaa
     2941 gttaactgaa tttgttgaaa atacaggagc ttataaagtt actgaatatg tacttataaa
     3001 agatgataag gaaatgctaa aggaaaatat tataagactt tgtaatagta ataaaataga
     3061 tttaattctt acaaatggag gtactggttt ttcaaaaaga gatataaccc cagaagcaac
     3121 taaggaagtg ttggaaaaag aaataccagg tctgagcgaa tatatgagaa tgaaatccac
     3181 agaaattact aaaaaggcca tactaagtag gggtgtaagt ggaataagaa ataattctat
     3241 aataataaat ttacctggaa gtcctaaagg tgcagttgaa aatctaagtt ttataattga
     3301 tgttttagac catggcatag aagttttaag aggagaagct acagaatgtg ccactaaaaa
     3361 aagtgaatag tatataatct agatagataa aaaatagaca aagaggtaga taaagtatga
     3421 ttgataagta tggaagaaaa atagactacc ttcgtatttc acttacagat aagtgtaatt
     3481 taaggtgtgt ttattgtatg ccaccagatg taaaatttga taaaaattat ataaatgaaa
     3541 atctaagctt tgaagactac aagtttatta taaaggctat ggctgaacaa ggtataacaa
     3601 aaattagatt tactggagga gaacctcttt tatatcctaa attaaatgag cttataaaat
     3661 ttacaaaaga agaatgtgga ataaataaca taggaatgac cactaatgct attgggcttt
     3721 ctgatagaat ctttgagctt gaaaaatgtg gcttaaataa agttaatata agtttagatt
     3781 ctttgaagga atataagtat aaatccgtaa caagaggagg aaacttaaaa gatgtcttaa
     3841 aatcgattga atcttgttta aacttaggta taaaagtaaa gttaaattgc gttgctataa
     3901 gtgggtttaa tgatgatgag cttaaagatt ttatgttttt aacagttaaa tcaccaattg
     3961 atgtaagatt tatagagctt atgccattag gtgaggctaa tagagtttat aagaagggtt
     4021 attttaatgt aaaagaaatg attgaaaaaa tatatggttt atataaagtc aaaaatgatg
     4081 aaaaaagtac agcagaatat tatatgttta aaggagctaa aggaagaata ggaattataa
     4141 ctccattaag ctgttcattt tgtaacactt gtaatcgtat tagacttact tctagtggtg
     4201 caataaaatt atgtctacat tcaaaagaag aaatagatat aaaaccattt ttacataaac
     4261 cattgttatt tagagaatct atgaaagata taataaaaca aaaaccagaa aaacatcatt
     4321 taatagaaaa taaatgtagt gatacaaata ggcgtatgta tgaaattgga ggataagtaa
     4381 tgttaacaca tataaatgaa aaagggtatg ccaagatggt ggacataagt gaaaaagatg
     4441 atactaaaag aacggccgta gctacagcta caattactct tagtaaggaa gcattagaaa
     4501 aagtaaaaaa tggtcagata aaaaaaggag acgtattgtc tgtagctcaa gttgcaggta
     4561 taatgggagc taaaaataca tcttcaaaca taccaatgtg ccatcagatt aaattagttg
     4621 gatgtgattt agaatttgat gtagatgatt ctatgtctgc tattaagata tacgcaacct
     4681 gtaaatctct tgggaaaact ggagtagaaa tggaagcttt aaatgcatgt tctttagcag
     4741 cacttacaat ttatgatatg tgtaaagcag ttgataaaaa aatggttata agtaatatcc
     4801 atcttgtaga gaagactggt ggaaaatcag gagattttaa gttcgagtaa attaataata
     4861 tattgggtta aaatttggag gaaatatggc gaaggtagtg tcaataaata taagtgagaa
     4921 aaaaggtgta attaaagttc ctgtacaatg tgcagagcta aaaataaatc atgggatagt
     4981 tggagatgca catgcaggaa actggcatcg tcagataagc ttacttggaa aagaaagcat
     5041 agataaaatg aaaatgaaag gctttgacca attaaaatat ggagattttg ctgaaaatgt
     5101 aactacagaa gggatagaag ttttttccct gcctgttggt acaaagttaa gaatagggca
     5161 atgtgaagtt gaagtaactc aaatagggaa aaaatgtcac aatggatgcg aaattaagaa
     5221 attgacaggt gactgtgtga tgccacgaga aggaattttt gtaaaggttc taaaagaagg
     5281 aattataaat gtgaatgatt caatagatgt aatctaatga agtcactatt aaaatataat
     5341 tataagtaaa tactattaag atttaaatat atattttaag agagaattaa ttttaataaa
     5401 atattttagt tataaattgg aatattggtt atataaagct atgaatgtaa aatcatagct
     5461 ttttgttttt gaattttaaa atataatatt ttatttatat atattaaatt atattttata
     5521 taaaatcaat tgtttaaata tatattattt atactgtaaa tttatagata ataaagtata
     5581 aaaaaaatat at
//
LOCUS       DAEPKC010000156         5525 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.159, whole genome shotgun sequence.
ACCESSION   DAEPKC010000156 DAEPKC010000000
VERSION     DAEPKC010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5525)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5525)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5525
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.159"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            50..166
                     /gene="rrf"
                     /locus_tag="KR294_003552"
     rRNA            50..166
                     /gene="rrf"
                     /locus_tag="KR294_003552"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            complement(380..1564)
                     /locus_tag="KR294_003553"
     CDS             complement(380..1564)
                     /locus_tag="KR294_003553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBH0241598.1"
                     /translation="MLSKRLNFITPSYTIGISSKVKEMESNGVKVINLSIGEPDFNVP
                     NNAKSYGIDSLNKDYTKYDLVPGLKILREEICKKLIEENNCNYSIDEIVVSSGAKNSI
                     TNTLLALTDEGDEVLLPKPYWVSYPEMIKLVNAVPVFIDTKKENGFKLTKEELEKSIT
                     DKTKILVINNPSNPTGSVYTKDELIEIVDVCIQNKIYILADEIYEKICYTGEFTSIAS
                     LSEEAKDITITINGFSKSAAMTGLRLGYTASNKTIAKAMSSIQGHLISHPSLTAQYIA
                     YGALKDCSIDIDNMVKTYKSRRDLIKSKLDSIDNVGYVNPNGAFYIFIDLSKVSEKFE
                     YKDSFSIEFCNQFLEEYNVAVVPGIAFGMDKYIRISYACSENTFLSGLDKLKEFVYKI
                     MA"
     gene            1937..4288
                     /locus_tag="KR294_003554"
     CDS             1937..4288
                     /locus_tag="KR294_003554"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside triphosphate reductase"
                     /protein_id="HBH0241599.1"
                     /translation="MVEFVKKRDGRVIPFNEDRITRAIFLAATNVAEREGIVPDYKLS
                     EQLTQEVIKFLNHKYSESVPSVEDIQDSVVKVLIETGHAKTSEEYIIYRTERSRIRNS
                     KTRLMKAIEEITFEDAEDADIKRENANINGNTAMGTMLQYGSTVSKEFCKTHILKPEH
                     SFAHDNGDIHIHDMDFLNMGTLTCCQIDVKKLFNGGFSTGHGFLREPQDIISYGALAA
                     IAIQSNQNDQHGGQSIPFFDYGLAEGVYKTFKKFYIGNLAKALKLFKGIENNDVIKNI
                     VYNTEKETNQKVGLKRDELYLNLEKEKLIQTFDIDDELVNKMQNFAFEESYRETDKKT
                     YQSMEAFIHNLNTMHSRAGAQVPFSSVNFGTDTSEEGRMVTKNLLLSQERGLGNGETP
                     IFPILIFKVKEGINLNPEDPNYDLFKLSCRVSAKRLFPNFSFLDAPFNAKYYKKGEPD
                     TEATYMGCRTRVLSNVCGSETVSGRGNISFTTVNLPRLGIKHGIINNEKANLDGFFEE
                     LDEKINLIIEQLLERLEVQGNKKMKNFPFLMGQGVWKGSDDLGPEDTLKEVIKQGTLT
                     IGFIGLAECLIALIGKHHGESKEAQELGLKIVSHMRHKMDEATDKYKLNFSLMGTPAE
                     GLSGRFTKIDKKVYGEIKGITDKEYYTNSFHVPVYYNISAYDKIEIEAPYHELTNAGH
                     ITYVELDGDPSDNLEAFETVIKAMKDLGIGYGSINHPVDRDPICGFSGVITSNICPVC
                     GRNEDESDIKFERIRRITGYLVGTVDRFNNAKKAEVRDRVKHR"
     gene            4310..4849
                     /gene="nrdG"
                     /locus_tag="KR294_003555"
     CDS             4310..4849
                     /gene="nrdG"
                     /locus_tag="KR294_003555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HBH0241600.1"
                     /translation="MKIRMSSTISYDSIVDGPGLRMVIWTQGCIHNCKECHNPQTHDL
                     CGGFYMDTEEIINKVKSLKLQKGITLSGGEPFLQPEPLEEIAKEAKINGLDVWSYTGF
                     TFEQLLDKKNRAYFKNLNLLKQIDILVDGKFIAEKKDISLKFRGSSNQRIIDVQKSLK
                     YKQVFLVEQYMKDDLSIAE"
BASE COUNT         2151 a          625 c          888 g         1861 t
ORIGIN      
        1 ttctataaac ttattaaaaa cttaatagaa atattaagca taaagattat gtggttacaa
       61 tagcagagag gatacacctg ttcccattcc gaacacagaa gttaagctct ctagcgctga
      121 tggtacttgg tgggaaactg cctgggagag taggacgtag ccacgtaatt tttttgttat
      181 aataaattta gaatttaact tatatagttt aatttgataa tttgatgaaa aaaataaaag
      241 acttattgat ttttaaatct ataggtcttt tattttttat ctaacattta aattaagttg
      301 ttgaatatat cttatattac ttaccttata tattaattat cattaataca ttatatctaa
      361 ttactattca tctaaattat tatgccatta ttttatatac aaattctttt aatttatcta
      421 atccagataa gaaagtattt tcactgcaag cataggatat acgaatatat ttatccatac
      481 caaatgctat gccaggaaca actgcaacat tatattcttc taaaaattga ttacaaaatt
      541 ctatagaaaa actatcttta tattcaaatt tctcagatac tttagaaaga tctataaata
      601 tatagaatgc gccatttgga ttcacatatc ctacattatc aatagagtct agttttgatt
      661 taattaaatc tcttcttgat ttatatgttt taaccatatt gtctatgtca attgagcaat
      721 ctttcaaggc tccataggct atgtattgtg ctgttagact tgggtgagat ataagatgtc
      781 cttgtataga actcattgct ttagcaatcg ttttattaga tgcagtatat cctaatctta
      841 atccagtcat tgcagctgac ttagaaaaac catttatagt tattgttata tctttagctt
      901 cttcgcttaa tgatgcaatt gatgtaaatt caccagtgta gcatattttt tcatatattt
      961 catctgctaa aatatatatt ttattttgta tgcatacatc tactatttct attaattcat
     1021 cttttgtata aacactacca gtaggatttg aaggattgtt tattacaaga atttttgttt
     1081 tatctgttat agatttttca agttcttctt ttgttaactt aaatccattt tcttttttag
     1141 tatcaataaa aactggaaca gcattaacta acttaatcat ttcaggataa ctaacccaat
     1201 aaggctttgg taataagact tcatctcctt cgtctgttaa agctagtaaa gtatttgtta
     1261 ttgagttttt tgctccactt gatacaacta tttcgtctat tgaatagtta cagttatttt
     1321 cttcaataag ttttttacag atttcctctc taagtatttt taatcctgga actaaatcat
     1381 atttagtgta atctttattt aaagaatcaa taccataaga ttttgcgtta ttaggtacat
     1441 taaaatcggg ttctcctata ctaagattta ttactttaac tccattactt tccatttctt
     1501 taactttaga actaatacct attgtgtagg atggtgttat aaagtttagt ctttttgata
     1561 acataaaatg cctcctttta aattattatt tatattatac gacaaattta aagaatttac
     1621 ataaggaaat ttgtagatat atacattaat atatataata gcctacactt tttgcctaaa
     1681 attagtgtaa aaaaaagaga aaaaaatttt aactttcaaa gttgttagaa acgctactgt
     1741 tcaaaatatc cacatagtat ttgcaatgat ttgcgcaagt ttgactatta tgtacaaatt
     1801 tggtaatctt aatatagcaa ttattaagat aatcccttta acttagttga aggggatttt
     1861 tttagactta acatactaca tatagtggta tggggattaa taaaatacaa tatatagtaa
     1921 caggaggttt ttttaattgg ttgaattcgt aaaaaaaaga gatggaagag taattccatt
     1981 taatgaagat agaataacaa gagctatatt tttagcagca acgaatgttg cagaaagaga
     2041 aggaatagta cctgattata aattatctga gcaattaact caagaagtaa taaagttttt
     2101 aaatcataaa tactcagaat cagttccaag tgttgaagat atacaagatt ctgtagttaa
     2161 ggttcttata gaaactggcc atgcaaaaac tagtgaagaa tatataatat acagaactga
     2221 aagaagtaga ataagaaatt caaaaacaag gttgatgaag gcaatagagg aaattacctt
     2281 tgaagatgca gaagatgctg atataaaaag agaaaatgca aatattaatg gtaatacagc
     2341 aatgggaact atgttacaat atggaagcac tgtatctaaa gaattttgta aaacacatat
     2401 attaaaacca gagcattctt ttgctcatga taatggagat atacacatac atgatatgga
     2461 ttttttaaat atgggaacat taacttgttg tcaaatagat gttaaaaaac tattcaatgg
     2521 tggattttca acaggacatg gctttttaag agagccacaa gatataataa gttatggtgc
     2581 attagctgca attgctatac aaagcaatca aaacgatcaa catggaggtc aaagtatacc
     2641 atttttcgat tatggattgg ctgaaggtgt atataagaca tttaagaaat tctacatagg
     2701 aaatttagct aaagcattaa agttatttaa aggaattgaa aataatgatg tgataaagaa
     2761 catagtatat aatacagaga aagaaacaaa tcaaaaagtt ggtcttaaga gagatgaatt
     2821 gtatctaaac ttagaaaaag agaaattaat acagactttt gatatagatg atgaacttgt
     2881 aaataagatg caaaactttg catttgaaga atcgtataga gaaactgata aaaaaacata
     2941 tcaatctatg gaagcattta tacacaatct aaacacaatg cactctagag caggtgcaca
     3001 ggtaccattt tcaagtgtaa acttcggaac agatacttct gaagaaggaa gaatggtaac
     3061 taagaatctt ctattatctc aagaaagagg tttaggtaat ggagagacac caatttttcc
     3121 aattttaata tttaaggtca aagaaggcat aaatttaaat cctgaagacc ctaattatga
     3181 tttatttaaa ttatcatgca gagtatcagc taaaagacta ttccctaatt ttagtttttt
     3241 agatgcgcct tttaatgcaa aatattataa aaaaggtgaa ccagatacag aagctacata
     3301 tatgggttgt agaacaagag tacttagtaa tgtgtgtggt tcagaaacag ttagtggtag
     3361 aggaaacata tcttttacta cagtaaattt accaagattg ggtataaaac atggtattat
     3421 aaataatgaa aaggctaatt tagacggttt ctttgaagaa ttagatgaga agataaactt
     3481 aattatagaa caattattgg agcgccttga ggtacaagga aataaaaaga tgaagaattt
     3541 tccattctta atggggcaag gtgtatggaa aggttctgat gatttaggac cagaagatac
     3601 actaaaagaa gtaataaaac aaggaacatt gacaattgga tttataggtt tagcagagtg
     3661 ccttattgct cttataggta aacatcatgg agaaagtaaa gaagctcaag aattaggatt
     3721 aaaaatagtg tcacatatga gacataaaat ggatgaagca acggacaaat ataaattaaa
     3781 tttctcctta atgggtactc cagcagaagg tctttcaggt aggtttacta aaatagataa
     3841 aaaagtttat ggagaaatta aaggtatcac agataaagaa tattatacta attcattcca
     3901 tgtaccagtt tattacaata taagtgcata tgataaaatt gagatagaag ctccatacca
     3961 tgaattgact aatgcaggtc atataacata tgtagagtta gatggagatc catctgataa
     4021 tttagaagct tttgaaactg ttataaaagc tatgaaagat ttgggtatag gatatggaag
     4081 tataaatcat cctgtagata gagacccaat atgcggtttt tcaggtgtaa taacaagtaa
     4141 tatatgccct gtatgtggaa gaaatgaaga tgaaagtgat atcaaattcg aaagaataag
     4201 aagaataaca ggatatttag ttggtacagt tgatagattt aataatgcta aaaaagcaga
     4261 agtaagagat agagtaaaac atagatagtt ttatttgggg gaataagtta tgaaaataag
     4321 aatgtcatct actataagtt atgacagcat agttgatgga ccaggattaa gaatggtaat
     4381 atggacccaa ggatgtattc ataattgtaa agagtgccat aatcctcaga cacatgattt
     4441 atgtggagga ttttatatgg atacagaaga aattataaat aaagtcaaat cattgaaatt
     4501 acaaaaaggc attacgctat caggaggaga accattttta caaccagaac cattagaaga
     4561 aatagcaaaa gaagctaaaa taaatgggtt agatgtatgg tcatatactg gatttacgtt
     4621 tgaacaactg ttagataaaa aaaatagagc gtattttaaa aatttaaatt tactaaagca
     4681 aattgatatt ttagtggatg gaaaatttat agctgaaaaa aaagatataa gcttaaagtt
     4741 tagagggtca tcaaatcaaa ggataattga tgttcaaaaa agtttgaaat ataaacaagt
     4801 gtttttggtt gagcaatata tgaaggatga tttatctata gcagaataaa atataaataa
     4861 acaggattaa atatatgcat atatttaatc ctgtttattt tcatataata tttcaagctt
     4921 gtataatgta acaattaaac caaaagactc attgtatatt tgaaattaag ttttttatag
     4981 tttataggtg ttttatgtgg attacgaatg atatagtatt gatacattat ttaatagatt
     5041 cttatgccaa gaaacaatta atttatagaa attcttaatt gttacaatat aaatatctag
     5101 atatgttata agatactgat aaataattta taaagtttat taatctaata ttgtgtgtga
     5161 atattaagtg gtcaagtagt ctaaaaaatg aaaaagattt aaaaaagtgt tttaactaaa
     5221 cacataagtg ttaaattcat gtataagtat aggttagata cataagaaat aattatgtaa
     5281 tatctatctt tgtaaaaaaa tattaaattt tgtaatttgt ggataaatat gtttataatg
     5341 tggataatat ttaatgtaat aagttaaagc aatatgaatc aactgtttat aatgtggata
     5401 atattataaa tgtatgaata attgcagtat ttaaaaacaa aaaaagttaa aaaagttgtt
     5461 gactctaaaa gaaaaagttg gtatagtaat acttgtcctc aagaaaaggg caaacaaata
     5521 aagca
//
LOCUS       DAEPKC010000157         5427 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.160, whole genome shotgun sequence.
ACCESSION   DAEPKC010000157 DAEPKC010000000
VERSION     DAEPKC010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5427)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5427)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5427
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.160"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            123..791
                     /locus_tag="KR294_003556"
     CDS             123..791
                     /locus_tag="KR294_003556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YwaF family protein"
                     /protein_id="HBH0241601.1"
                     /translation="MFKIFLFSSEQFVSLFIFGLFLYYCPKLTKNILPYSYTVEKIIC
                     TLLVIIMALEQLLLISSGNYSTLNSLPIGINYICIYLCIAILIFKQYHLFNIFFSWSL
                     VCSVGELIFSKNLGYEFPSLIYFIFIFSKCLIIYADIYMVDVRKFRVNRYALRDNLAI
                     CFIYFSFIFLLNTFTNSRYYYGFLSHSTTAIFTFIFVTSIMYIPALLFNRDTFILEKK
                     KKSK"
     gene            complement(882..2333)
                     /locus_tag="KR294_003557"
     CDS             complement(882..2333)
                     /locus_tag="KR294_003557"
                     /EC_number="3.4.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucyl aminopeptidase"
                     /protein_id="HBH0241602.1"
                     /translation="MNIKYSKEILKSLENAITVVALFEGEDVSTTFDKINMISRNFNS
                     KENSIDTVTLIENNNLVNVCLVGFGKRELLNREKIRIIGGNLCKKLKNILKNEAYKSS
                     DVNVLNLNLNSDEIGSFVEGILLGNYKFDKYKTKIKDFERKEVDTITIFTEKEVECQI
                     EKAKILANSTIIARNLVNEPSNVIYPKTLAVETVKLGAEFGFNVDVYEEEKIKALGMD
                     AFFAVSRGSINKPRFIVMRYFGDKESTDILGLVGKGLTYDTGGYSLKSNASMLDMKTD
                     MAGAASVIGAMCAISQSKLKKNVIAVVAACENALSGGSYKPGDIISSMAKKTIEVLNT
                     DAEGRLTLADAIYYIINNEKVTKVVDVATLTGAALTLLGNVATPIVTNNDDFYCELEK
                     AATLSGERVWKMPIYDEFKDMIKGEEADLKNTGGKNAGCITAGAFIGEFVGNTPWIHM
                     DIAGTSTSSKSIGYKAKGATGEPVRTLYYLAEI"
     gene            complement(2349..2789)
                     /locus_tag="KR294_003558"
     CDS             complement(2349..2789)
                     /locus_tag="KR294_003558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBH0241603.1"
                     /translation="MSDKELSILLLESMNNFHNLIKIINNERYKKDKVLTERQFFALV
                     KIRKHDKIELKNLSRDLHVSTSSLCILLNKLVEQEYVYREEDSRDRRNTFYGITKNGE
                     KILDNEILKFVSIISDKMDCLDIDNKDKLFTSLEESKNIIEQLF"
     gene            complement(3037..3465)
                     /gene="ytfJ"
                     /locus_tag="KR294_003559"
     CDS             complement(3037..3465)
                     /gene="ytfJ"
                     /locus_tag="KR294_003559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GerW family sporulation protein"
                     /protein_id="HBH0241604.1"
                     /translation="MRATGSIQSLMETTLETIKGSIDANTIIGDPIKTDTTVVVPISK
                     VTIGFGIGGGEYSKGYDDKDREIELKNEKSDTNFAGGSAGAISVQPVAFVVVESGETR
                     IMSLDSNINLVDNILSITPRVLEKIQNISQSNKNQDKNNM"
     gene            complement(3419..4048)
                     /locus_tag="KR294_003560"
     CDS             complement(3419..4048)
                     /locus_tag="KR294_003560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2953 domain-containing protein"
                     /protein_id="HBH0241605.1"
                     /translation="MELNELFNFKYLIIAVIFIISVTMLILISHINILIIADIKNKDI
                     CLKLNIKYMFNLININRQLYPAENSKNNDKKEGMKNNIDSSILLADDLLSIYRLLKKI
                     KIHELYSNINFGTGNIGLTSSVYVLINTLYGNLFNMIDAEKMYLNVNPDFTKDYVLGN
                     IRIHIRPRIKALFNIIIMINKIMNKNKGNKEGDSNESNRFDTESYGNNS"
     gene            complement(4210..4749)
                     /gene="scpB"
                     /locus_tag="KR294_003561"
     CDS             complement(4210..4749)
                     /gene="scpB"
                     /locus_tag="KR294_003561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HBH0241606.1"
                     /translation="MKREDIKYIIESVMFAYGEPISIKELNYIINKELSSKEIEIMLN
                     LLIEEYREQNRGIQIIKLENKYQMCTNKDYAEYIKKIIEPKKKKSLSQATLETLTIIA
                     YKQPITKVEIEDIRGVKCDKVLQTLFENELIREAGRLNKIGKPIIYKTTDEFLKLLNI
                     ESLEELPPIENYQEVATNE"
     gene            complement(4751..>5427)
                     /locus_tag="KR294_003562"
     CDS             complement(4751..>5427)
                     /locus_tag="KR294_003562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HBH0241607.1"
                     /translation="LLYDLITKHKIDIKDISIIDITKQYLNYLKMLDKMDLEITSEFI
                     TMASKLLEIKSKYLLYKQKDEEEDPRIELMEKLEEYRKFKVASQDIKENITYVNERFY
                     RNKEEIIIDDNVDLEDISIEAIKNILPYIFKVKTSQIENANDEKLDKIVRKKIISVEE
                     KILYIRDIIKEKIEVTFTNIIKSYENDEIIATFLSILELIKEKEIVVVQDIFFDDILI
                     RKSSEC"
BASE COUNT         1724 a          892 c          470 g         2341 t
ORIGIN      
        1 tttacctatt aaaattcata taaaaaatct aactattatt atctttttta tatattaaat
       61 tgagatataa tgaatatatt tatatagata catattaaat ttattatagg agagaatgtt
      121 atatgtttaa aatttttctt ttttctagtg aacaatttgt aagtctcttt atatttggat
      181 tatttttata ctattgtcca aaactaacca aaaatatttt accttatagc tatacagttg
      241 agaagataat ttgtacatta cttgtaataa ttatggctct agagcaatta ttacttattt
      301 cttcaggtaa ttatagtact ctaaactctt taccaattgg aatcaattat atttgtatat
      361 atctgtgtat agccatacta atttttaagc agtatcatct ttttaatata tttttttctt
      421 ggagtttagt ttgttcagtt ggagaactca ttttttctaa aaacttgggc tatgaatttc
      481 ctagcttaat atattttatc tttatcttct ctaagtgctt gataatttat gcagatatat
      541 atatggttga tgttagaaaa tttagagtta acagatatgc acttagagat aacttagcta
      601 tatgttttat ttatttttca ttcatatttt tactaaacac attcaccaac tctaggtact
      661 attatggttt tttaagtcat agcacaactg ctatttttac gtttattttt gttactagta
      721 ttatgtacat acctgctctt ttatttaata gagatacttt tatacttgaa aaaaagaaaa
      781 agagtaaata atttatttaa ataaaaaata aagccacata gataatctta aattacaaaa
      841 atatccacgt ggctttataa attatatttt ataattgttt tttagatttc tgccaaatag
      901 tacaatgttc taacaggttc tcctgtagcc ccctttgctt tgtatccaat tgattttgat
      961 gatgtacttg tccccgctat atccatatgt atccaaggag tattcccaac aaattcacca
     1021 ataaaagctc ctgctgttat acatccagca tttttaccac cagtgttttt aaggtctgct
     1081 tcttctcctt ttatcatatc tttaaattca tcataaattg gcatcttcca taccctttcc
     1141 cctgataaag tggcagcttt ttctaattca caataaaaat catcattatt tgttactata
     1201 ggagttgcaa cattacctaa caatgttaaa gcagcaccag ttaatgtagc tacatcaacc
     1261 acctttgtta ctttttcatt gtttataatg tagtatattg catcagctaa tgtaagtcta
     1321 ccttctgcat ccgtatttaa aacttcaata gttttctttg ccatagaact aattatatct
     1381 ccaggtttgt atgaacctcc tgataaagca ttctcacatg cagccactac tgctataaca
     1441 tttttcttta atttactttg agatatagca cacatagcac ctataacact cgcagcacca
     1501 gccatatctg tcttcatatc tagcatagaa gcatttgatt ttaaagaata tccaccagta
     1561 tcataagtca atcctttacc tactaaacct aatatatctg tactttcttt atctccaaag
     1621 tatctcatta ctatgaatct tggtttatta attgagcctc ttgaaacagc gaaaaaagca
     1681 tccattccca atgcctttat tttttcttct tcataaacat caacattaaa cccaaactct
     1741 gcaccaagtt taactgtttc tactgctaat gtttttggat atattacgtt tgatggttca
     1801 ttaactagat ttctagctat tatagttgaa ttagctaata ttttagcctt ttctatttga
     1861 cactcaactt ctttttcagt aaatatagtt atagtatcaa cttcttttct ttcaaaatcc
     1921 ttaatttttg tcttatactt atcaaactta taatttccaa gtaatatccc ttctacaaaa
     1981 gaacctattt catcactatt taaattaaga ttcagtacat taacatcact actcttatat
     2041 gcttcatttt tcaatatatt ttttaatttt ttacacaaat taccacctat gattctaatt
     2101 ttttctctat tcaataactc tctcttacca aaaccaacaa gacaaacatt taccaaattg
     2161 ttattttcaa tcaatgttac agtatctata ctattttctt tagaattaaa atttctgctt
     2221 atcatattta ttttatcaaa tgtcgtagaa acatcttctc cctcaaatag agctactact
     2281 gttatagcat tttctaaact ttttaatatt tctttagaat actttatatt cataataaat
     2341 tctccttttt aaaataattg ttctattata tttttagact cttccaaaga agtaaataat
     2401 ttatctttat tatctatatc taggcaatcc attttatcac ttattataga tacaaacttt
     2461 agtatttcat tatccaatat cttttctcca tttttagtta ttccataaaa agtatttcgt
     2521 ctatctctac tatcttcttc cctatataca tactcttgct caaccaattt attaagtagt
     2581 atacacagac tagaagtaga tacatgcaaa tctctactta gatttttaag ctctatttta
     2641 tcatgttttc ttatttttac taaggcaaag aactgtcttt ctgtaagaac cttatctttt
     2701 ttatatcttt cgttattaat aatctttatt aaattatgaa aattattcat actttctaac
     2761 aacaaaatag ataattcttt atcgctcata acattcacct caaaactaat gatttataac
     2821 tccctcttat atctcaaatg cgtttatata tctataatat aatacttctt ttctttttat
     2881 aattatacta tatatcaact ttattatcta tttaaattgt tttaaactaa aatcttatta
     2941 gatataaatg tttaaagtac acaacaaaat agtgggattt atactaaccc cactacttta
     3001 cctaaaacta tatacatatt taaaaatatt ttattcttac atattgtttt tatcttgatt
     3061 cttattactt tgtgatatat tttgaatttt ctccaatact ctaggagtta tagataatat
     3121 attatccact agattgatat tactgtctaa actcattatt ctagtctctc cactttcaac
     3181 tactacaaat gctactggtt gtacagatat agcccctgcg ctacctccag caaaattcgt
     3241 atctgatttt tcatttttta attcaatttc cctatcttta tcatcatatc cttttgagta
     3301 ttctcctcct cctataccaa agccaattgt aacctttgat ataggtacaa ccactgtagt
     3361 atctgttttt atagggtctc ctataatagt atttgcatct atagaacctt taattgtttc
     3421 aagagttgtt tccataagac tctgtatcga acctgttgct ctcattacta tcaccttcct
     3481 tatttccttt atttttattc ataattttat taatcattat tataatatta aataaagctt
     3541 ttattcttgg ccttatatgt atccttatat ttcctaaaac ataatctttt gtaaaatctg
     3601 gatttacatt taaatacatt ttttctgcat caatcatatt aaataaattt ccatacaaag
     3661 tatttatcaa tacatataca gaagatgtta agccaatatt tccagttcca aaattaatat
     3721 ttgaataaag ttcatgtatt tttatctttt ttaataatct ataaatgctc aaaaggtcat
     3781 cagctaataa tatacttgaa tctatattat tcttcatccc ctctttttta tcattatttt
     3841 tactattttc agctggataa agttgtctat ttatatttat taaattaaac atgtatttta
     3901 tattaagctt taaacaaata tctttgtttt ttatatcagc tattattaag atgtttatat
     3961 gagatattaa aatcaacata gttacactta taataaaaat tacagctatt attaaatact
     4021 taaaattaaa taattcatta agctccatgt ttatattatc atcaaaaaat tactatttat
     4081 acttaattat ccatatttat tttaagagaa ttataatttt atatttatac aaaaaaacac
     4141 aacaacttag agcattttaa atcttttaaa atttaaaatt acatactaaa ttattgtgat
     4201 tttatatttt tattcatttg ttgccacttc ttgataattt tctataggtg gcaattcttc
     4261 aagactttct atattcaaca actttaaaaa ttcatctgtt gttttataaa ttattggttt
     4321 ccctatctta ttcaatctac cagcttctct tataagttca ttttcaaaca aagtttgtaa
     4381 taccttatca cattttactc ctcttatatc ctctatttct acctttgtta ttggttgttt
     4441 gtaggcaatt atagtaagag tttctaatgt agcttggctc aaacttttct ttttctttgg
     4501 ttcaataatc ttctttatat attctgcata gtctttattt gtacacattt ggtacttatt
     4561 ctctaacttg attatttgaa tacctctatt ttgttctctg tactcctcaa taagtaaatt
     4621 taacataatc tctatttctt ttgatgaaag ttctttattt attatatagt ttaattcttt
     4681 tatacttatt ggctcaccat atgcaaacat aacagattct ataatatact ttatatcttc
     4741 tcttttcatt ttaacactcc gaactttttc ttattagaat atcatcaaaa aatatatctt
     4801 gtactacgac tatttctttt tcttttataa gctctaatat agataaaaaa gtagctatta
     4861 tttcatcatt ttcatatgat tttataatat ttgtaaaagt aacttcaatc ttctctttta
     4921 taatatctct tatatataat attttttctt ctacagatat tattttcttc cttactattt
     4981 tatctagttt ctcatcatta gcattttcta tctgtgatgt tttaacttta aatatgtatg
     5041 gaagtatatt ttttattgct tcaattgata tatcttctaa atccacattg tcatcaataa
     5101 ttatctcttc tttatttcta taaaatctct cattaacata agttatattt tcttttatat
     5161 cttgtgatgc taccttaaac tttctatatt cttctaactt ttccataagt tctattcttg
     5221 ggtcttcttc ttcatctttt tgcttataaa gcagatattt agactttatc tctaaaagtt
     5281 ttgatgccat agttataaat tcactagtta tctctaaatc cattttatct agcattttca
     5341 aataatttag atactgctta gttatatcta ttatggatat atcctttata tctattttat
     5401 gctttgttat taaatcataa agtaaat
//
LOCUS       DAEPKC010000158         5383 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.161, whole genome shotgun sequence.
ACCESSION   DAEPKC010000158 DAEPKC010000000
VERSION     DAEPKC010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5383)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5383)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5383
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.161"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(392..1984)
                     /gene="hcp"
                     /locus_tag="KR294_003563"
                     /gene_synonym="priS"
     CDS             complement(392..1984)
                     /gene="hcp"
                     /locus_tag="KR294_003563"
                     /gene_synonym="priS"
                     /EC_number="1.7.99.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxylamine reductase"
                     /protein_id="HBH0241608.1"
                     /translation="MEKMFCFQCEQTAGGKGCTINGVCGKKGGTANLQDELTGVLIGL
                     SRATIGNKNRPTSETDKIMIEGLFTTITNVSFDDEAIKRQIEKTEVEKSKLVPRCSDC
                     STTCNRNDNYDMKDLWNDNEDIRSLKSLILFGLRGMAAYAYHAMVLGYTDKDVNEFFY
                     EGLIAVGGDLSIDELLGLVMKTGEINLKCMELLDRANTETYGTPEPTQVSMKIEKGPF
                     IVVTGHDLYDLHKLLEQTKDKGINIYTHGELLPAHAYPKLKEYKHLKGNFGTAWQNQQ
                     KEFDNIPAPILFTTNCLMPVKDSYRDRVFTTEVVAYPGMVHIDEDKDFSSVIEKALEL
                     GGYREDVHMTGINGGDTLTTGFARGTVSSVQDKVVDAVKSGAIRHFLLVGGCDGAKPG
                     RNYYTEFVKQAPKDTVILTLACGKYRFNDLDLGDICGLPRLMDMGQCNDAYSAIKVAV
                     SLANAFECGVNDLPLSMVLSWYEQKAVCILLTLLHLGIKNIYIGPSLPAFLSKNVLDI
                     LVDKFALTPISTPEEDMKKILG"
     gene            complement(2044..2769)
                     /locus_tag="KR294_003564"
     CDS             complement(2044..2769)
                     /locus_tag="KR294_003564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBH0241609.1"
                     /translation="MMRKIIKIDEEKCNGCGLCVEACHEEAIGMVNGKAKLLRDDYCD
                     GLGDCLPTCPTNAISFEYREAAEYDEAAVKANMEAKKAQKKTLACGCPGSQSKSINRE
                     VSNSMSISNDIVEIKGSQLNQWPVQIKLVPTNASYLKNASLLIAADCTAYAYGNFHNK
                     FMKNKVTLIGCPKLDEVDYAEKLTEILKENDIKNIVVTRMEVPCCGGIVNAVKTALQN
                     SGKMIPWQIVTISVDGKIVDGEI"
     gene            2934..3638
                     /locus_tag="KR294_003565"
     CDS             2934..3638
                     /locus_tag="KR294_003565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBH0241610.1"
                     /translation="MQQGSDYLKKFLEKHIDLLKKIPLFEGIKSDELEEMLECLGVVD
                     KTYTKDSIIFSVGSEVTSIGIMLKGSAHIIKEDIEGNRNIVAELLPGDLFGEVFACTR
                     LHKSNVTVTTTSSCEVLFIKFKSVTGICSSACVFHNRLVENMLQLIAEKNILLHNKIE
                     LLSRKTTREKLLMYFSKQIEQTGSHQFTIPFSRNEMADFLCVDRSSMSRELGKMRDEG
                     LLSFNKNKFEIFYFKK"
     gene            complement(3802..5073)
                     /locus_tag="KR294_003566"
                     /pseudo
     CDS             complement(3802..5073)
                     /locus_tag="KR294_003566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017416360.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="dicarboxylate/amino acid:cation symporter"
BASE COUNT         1797 a          929 c          629 g         2028 t
ORIGIN      
        1 ttaaaattag aatttttcat atacatatac ccccacataa aacaccttat attttaaatt
       61 ttaatcaaaa taatttcact atagtatata tattttatgc aagttacata ttacaatgtt
      121 cctcttttaa tatttaagtt acattcaaac ctttaatact taaaataaaa tatataagat
      181 attatatatc taagtattat aaatttaata caaagattct taaaaagaat atactgaaag
      241 caggtttatt tttcaattat tacaaaaaat aaataaaggg tcatctcaaa attgattttt
      301 taatcaaatt ttaagtttaa ccccttatct taattgtggc atacttaaaa atattttaac
      361 tataaatatc tttaagtata gatatgttta tttatcctaa aatcttcttc atatcttctt
      421 caggagtaga tataggtgtc aatgcaaatt tatcaaccaa tatatctaat acattcttag
      481 ataagaatgc tggcaaagaa ggccctatat agatattttt gatacctaaa tgaagtagtg
      541 taagaagtat acaaacagct ttctgctcat accatgacag taccatgcta agaggcaaat
      601 catttactcc acattcaaaa gcatttgcca atgaaactgc cactttaatt gcactataag
      661 catcattaca ttgtcccata tccattaaac gaggtaagcc acatatatcc ccaaggtcta
      721 aatcattaaa tctatatttt ccacatgcaa gtgtcaatat aacagtgtct ttaggagctt
      781 gttttacaaa ttcagtgtaa taatttcttc caggttttgc accatcacaa cctccaacca
      841 ataaaaagtg tcttatagct ccactcttta cagcatctac tactttatct tgtacagatg
      901 aaactgtacc tcttgcaaaa ccagtagtta atgtatctcc tccattaata ccagtcatat
      961 gaacatcttc tctatatcct ccaagttcaa gagctttttc tattacacta gaaaaatctt
     1021 tatcttcatc aatatgaacc atacctggat aagcaactac ttctgtagta aatactctat
     1081 ctctataact atctttaaca ggcattaaac agtttgttgt aaataatatt ggagcaggaa
     1141 tattatcaaa ttctttttgc tggttttgcc atgctgtacc aaaattacct tttagatgtt
     1201 tatattcttt tagttttgga tatgcatgtg ctggtaataa ctcaccatga gtatatatat
     1261 ttataccctt atctttcgtt tgttctaata atttgtgtaa atcataaagg tcatgtcctg
     1321 taactacaat aaatggccct ttctcgattt tcatagatac ctgagtcggt tctggtgttc
     1381 cataagtttc agtatttgct ctatcaagca attccataca ttttaagttt atttctccag
     1441 ttttcataac tagacctaaa agttcgtcaa tagacaagtc tcctccaact gctattaatc
     1501 cttcatagaa aaattcattt acgtctttgt ctgtataacc aagtaccatt gcatgatatg
     1561 cataggcagc catacctctt aatccaaata agattaatga ttttaatgaa cgtatgtcct
     1621 cattatcatt ccataaatcc ttcatatcat agttatcatt tctattacaa gttgttgaac
     1681 aatctgaaca tctaggtaca agcttacttt tttctacctc agttttttca atttgtcttt
     1741 ttatagcttc atcatcaaaa cttacattcg ttatagtagt gaatagcccc tctatcataa
     1801 ttttatctgt ttcacttgtt ggtctattct tatttccaat agttgctctt gaaagaccaa
     1861 tcaacactcc tgtaagttcg tcttgtaagt tagctgtacc ccccttttta ccacagacac
     1921 catttatagt acaaccttta cctcctgctg tttgttcaca ttgaaaacaa aacatttttt
     1981 ccatttttta ttcctccctt tttatttatt aaaatttatt atatttttct ataattcact
     2041 taattaaatt tctccatcta caatttttcc atctacagat atagtaacta tttgccatgg
     2101 tatcattttt ccactatttt gtagagctgt cttaacagca tttactatac caccacagca
     2161 aggaacttcc atacgtgtta ctactatatt tttaatatca ttttctttta aaatctctgt
     2221 aagtttttca gcatagtcaa cttcatcaag tttagggcat ccgattaatg taaccttatt
     2281 tttcataaat ttattatgaa aatttccata tgcatacgct gtacagtctg ctgctattaa
     2341 aagacttgca ttctttaaat atgatgcatt agttggtact aattttattt gtactggcca
     2401 ttgattaagt tgagaacctt ttatctctac tatatcattg cttatagaca tactatttga
     2461 aacctctcta tttattgact tagactgaga acctggacat ccacatgcta aagttttctt
     2521 ttgtgctttc tttgcttcca tatttgcttt tactgcagct tcatcatatt ctgctgcttc
     2581 tctatactca aatgaaatcg catttgttgg acaagttggc agacaatctc ccagcccatc
     2641 acaatagtca tctcttaaaa gttttgcttt tccatttacc attcctatag cttcttcatg
     2701 acaagcttca acacatagtc cacaaccatt acacttttcc tcatcaattt taattatttt
     2761 tctcatcatt tatatcacct cataaaattt ttttaattta aagtattgat ttcttatata
     2821 tatattttta atacctatat ttctttattt caaatttctt gtagtaggat ttttatatcc
     2881 ccttgctttt ataaacttag tatagtacaa tgaaaacaaa ttatcggttg catatgcaac
     2941 aaggaagtga ttatttgaaa aaatttttag aaaagcatat agacctactt aaaaaaattc
     3001 ctctatttga aggaattaaa agtgatgaac ttgaagaaat gttggaatgt ttaggtgttg
     3061 tagataagac ttacacaaaa gatagtataa tattctctgt tggaagtgaa gttacttcta
     3121 ttggaattat gcttaaagga agtgctcata taataaagga agatatcgaa gggaatagga
     3181 atattgtagc tgaactcttg cctggagatt tatttggaga ggtattcgca tgtactagac
     3241 tacataaaag taatgttaca gtaaccacaa catcttcttg cgaagtttta ttcataaagt
     3301 ttaaaagtgt aactggtatt tgttcatctg catgtgtatt tcataatagg cttgttgaaa
     3361 atatgctaca attaatagct gaaaaaaaca ttttacttca caataaaata gaattacttt
     3421 ctcgtaaaac aactcgcgag aaattgctta tgtatttttc aaaacagata gaacaaacag
     3481 gtagccacca gtttacaatt cccttttcaa gaaatgaaat ggctgatttt ttatgtgttg
     3541 acagaagttc tatgtcaaga gagcttggca agatgcgaga tgaaggcttg ttatctttta
     3601 acaaaaataa atttgaaatc ttttatttta aaaaataaaa tagatattta aacatattta
     3661 tttcaatata tactatatta gttgattcaa attataaata tcatatttga atcttaaatt
     3721 tatattttta cttaaaaagt taataggtat ctaatttatt aaaattaaga tacctattaa
     3781 ctttattaat taagtgtaca attagcttat tttctttgta gtaattgctg ttttatctat
     3841 aagccaatct tttccttcta ctaatcttga aactaacatt gatgatactg tatttccagt
     3901 tgtatttaat atagtattag gaatatcagt tatagtagtt ataactgtta acagtggaat
     3961 tgcctccact ggaaaaccga agatgctaac cacgagcatc tcaccaataa gtcagccacc
     4021 tgctacagga gccataaata ctccaacaac aaatacagtt ataaataatt gacctatcgt
     4081 tgctggattt gccattccac tacctaaaat acctgataaa aatgccactt ttattattac
     4141 tgctaaaact gacccatctt tatgtatatt tattccaaga ggtataactg tttctgatat
     4201 atcatcagga actcctatat ttttactagc ttctaaattt gatggtatac atgctgaact
     4261 tgaagaagta gctagtgccg ttgctattgg ttttatagca tttctccaga attgtctaaa
     4321 cccttgtttt cctgcagata aaaaagcata cagactgtaa aataataaga aatacatggc
     4381 tgctgttagt gaataaatta caaacaccct tacatatcct tgaattattt tacttccaag
     4441 ttccccaatt attgtagctg tataacagcc tagccctata ggagcataaa gcatgaatat
     4501 acttactact tttaatattg cttccgttcc ttctgataaa agctttctta ttgtatttcc
     4561 cctatctccc atcatagcta ttgctgttcc aattaaaact gcaaatataa ctaattgtag
     4621 taaattacta ctggaaaata aatctccaaa atttttaact gtaatacttg atactacttg
     4681 gtctaataac gttccttttg attctaaagt ttctgcatct tgagtcacca ttaaattttt
     4741 tacacttgat acatctaatc ctttagacgg attaaataat aatgcagatg taatacctaa
     4801 aaatgcaatt acaagtgttg ttcccataaa tactatagct gtacccttca ttatttttcc
     4861 aaatcgttcc atatttttta tactagcaac acctgaagaa acactaagaa aaactaatgg
     4921 tactactatc attaatagag catttatgaa taaatctcca aatggtttta gtattgaagc
     4981 ttttggacca agtactaatc ctactatcgc ccctactata gtacatgcta aaagtataat
     5041 tgatgactta taatttttta aaaagtccct catttatatt ttcctttcta atgctttata
     5101 ttataaatta ccccaaatgc taaaaaaatt aaagtaaatt atctaatgcg cattaataat
     5161 ttttgtaatt ttccccaaca gctactttag caaatactgg aatatatgtc aatttctata
     5221 gtttttttgt atttttaacg ttttattaat agttcatatc tatatataaa tattaataaa
     5281 attctgcttt taaaactttt tttctagatt aattttaata aaacaaacaa tataaaaaaa
     5341 tatatataat attacttaat tattttcaaa tttaatactt tgt
//
LOCUS       DAEPKC010000159         5215 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.162, whole genome shotgun sequence.
ACCESSION   DAEPKC010000159 DAEPKC010000000
VERSION     DAEPKC010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5215)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5215)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5215
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.162"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(193..1599)
                     /locus_tag="KR294_003567"
     CDS             complement(193..1599)
                     /locus_tag="KR294_003567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH0241611.1"
                     /translation="MDSVKYILRRFIGSSILISLLFIVLNIAGFLLFSYMLFVSKYSD
                     NLDTSDSREIKSNLIMIEDNLILRNGKFILDDSSKEVLHKNKVWAMLIDNNGDRIWGF
                     DLPKEIPSHYTLTDVAKFSRFFLKDYPVYVWEHPNGILVTGYPKDKYTKFNLTYTVKE
                     IEQFPMLIIGMFLVNAIVTFLIALFIGLKMVKSIKPIITGIKLMSKGEPVLLQEKGIL
                     SDISKSINTVSKELQMKDEKLRKKEEARSNWIAGISHDIRTPLSMIIGYAGELEESSS
                     LSNREQEQVSIICNQGIKIRELVNDLNLVSKLEYNMQTLNCDKIRVSAFLRELISEFI
                     NNNLDNDFYVELDILNEDIIIDADKKLLKRAISNLIQNSITHNQQGCNIRVTSKSDLD
                     FCYIIVEDDGKGMSQERINSLLKSQNGLSEAYAKGQNHGLGILIVSGIINAHRGKLDI
                     TSIDSQGLKTILKLPLIK"
     gene            complement(1644..2351)
                     /locus_tag="KR294_003568"
     CDS             complement(1644..2351)
                     /locus_tag="KR294_003568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0241612.1"
                     /translation="MESIKDKKILVVDDHKELLKMIDEILRKEGFSRVFLASSYEEAV
                     RVFRNVKPDCAILDVVLPDGDGFSIMRKIRETSKIPVIFLSARGEDEDRLIGLGLGAD
                     DYIVKPFLPKELTLRLVGILNRVYVPIEEEELPVFKLGDSVVVNLNSACVEKDGQEIS
                     LTAKEHSLLLKLYENKGRIVTNDSLCQAIWGDDMYGYENTLMVHVRRVREKIEKTPST
                     PKHLITVRGLGYKLMIN"
     gene            2522..3436
                     /locus_tag="KR294_003569"
     CDS             2522..3436
                     /locus_tag="KR294_003569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0241613.1"
                     /translation="MEMIIRTQRLSKEYNKIFRVKDIDLRVPQGAVYGFLGPNGAGKS
                     TTLKMLLGLAKPTQGNINILGKELNEKNRISILKDIGSLIESPSYYGHLTGLENMTIM
                     QRLLDLPKKNVNEALKIVRLENQKNKKVSQYSLGMKQRLGIAMAIMKFPKLLILDEPT
                     NGLDPAGIEEIRELIKSLPEKYGMTVLISSHLLSEIDQIATSIGIINHGELVFQDSIK
                     ELHNRGQSQIAIKTKNVVSAQKLLNTKGYMSLIQDGYLTIENLKDSDVAKINGMLVHS
                     NIDVFRIEEHKKSLEDIFLELTGKAVTL"
     gene            3436..4197
                     /locus_tag="KR294_003570"
     CDS             3436..4197
                     /locus_tag="KR294_003570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0241614.1"
                     /translation="MKYLGLEFYKLKRKKIILMTFLFVAVEIMWCIINSNRAITRNPD
                     MLGGFEYSYMLMSFASLNGLFFPILISIITSRISDIEHKGDTWKLLKSSVTSLNSIYL
                     SKFLCSAILVSIPVLMQVLSIVLFGHFRGVIESISVSLLLKYTLGTILVSIAIIALHL
                     WIATVIPNQMIAITFGMIGSFIGLTSGLFYQGIRRLFIWSYYLELSPLSYAYDNVLGS
                     SVYRIDMNFSITILVFLIGMLIYYIGRNHLLKKEV"
     gene            4209..4946
                     /locus_tag="KR294_003571"
     CDS             4209..4946
                     /locus_tag="KR294_003571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0241615.1"
                     /translation="MLRKSVLGEILKLKNSFIWYVLLALPLISVLIGSGNFYLNQGIL
                     KKEWYSLWTQVSLFYGEFFFPILIAIFCAYICRLEHMNHNWNNVMTLPVNLKNIFLSK
                     LTVVSILTAITQVFFVIFYIVAGNMFGFSGSVPKELTGWIAKGWIISISIASIQLYMS
                     IKIRSFATPIGISLCLSLFGMGLIVAKPAVGIFFPYSMLGSAMGVIKQSALNVNDTIV
                     TICVAFITTIVFSEIANRNFRKNDVIS"
BASE COUNT         1786 a          803 c          688 g         1938 t
ORIGIN      
        1 gaaaattttg ataccatgag taactcagcc ataagcgcat aaagcacaag ttactcttta
       61 ctttaataaa acttgacaag aaaagaattt atccttattc tactctaata gagttaattt
      121 gtcaataaag aataaaatta ttttcaaaat attttcattc ttcattctta tctgttatta
      181 ttttataaaa tatcacttaa ttagaggtaa ttttagtatt gtttttagtc cctgactatc
      241 aatgctcgta atatctaatt tacctctatg tgcattaata atgccagata ctatcaaaat
      301 acctagacca tgattttgac ctttggcata tgcctcactt agtccatttt ggctctttaa
      361 taaactatta attctttctt gactcatacc ttttccatca tcttcaacaa ttatatagca
      421 aaaatctaaa tcagacttag aggtaaccct tatattacat ccttgttggt tatgagttat
      481 actattttgt attaaattac taatagccct ttttaataat tttttatctg catctataat
      541 aatatcttca tttagtatat caagttcaac gtaaaagtca ttatccaaat tattatttat
      601 aaactcagaa ataagctctc tcaaaaacgc agaaactcta atcttatcac aattcaatgt
      661 ttgcatatta tattcaagtt tagacactaa atttaggtca tttactaatt ctctgatttt
      721 aatcccttga ttgcatataa tagacacttg ctcttgttct ctatttgaaa ggctactgct
      781 ttcttcaagt tctccagcat atccaattat cattgaaagt ggagttctta tatcatgaga
      841 tattcctgca atccagttag acctagcttc ctctttcttc ctaagttttt catctttcat
      901 ttgcaactct ttagatacag tattaataga ttttgaaata tcacttagta ttcctttttc
      961 ttgtaaaagt actggttctc cttttgacat aagctttatg ccagtaataa ttggttttat
     1021 agatttcacc atttttaaac ctatgaatag agctattaaa aaagtaacta ttgcattaac
     1081 cagaaacata cctattatta acataggaaa ttgttctatt tccttaaccg tataagtaag
     1141 gttaaactta gtgtacttgt cttttggata acctgttact aatattccat ttggatgttc
     1201 ccatacatac acaggatagt cctttaaaaa gaaccttgaa aactttgcta catctgtcaa
     1261 agtataatga cttggaattt cttttggtaa atcaaatccc catattctat ctccattgtt
     1321 atcaattaac attgcccaaa ctttattttt atgtagtact tccttactag aatcatctaa
     1381 aataaacttt ccatttctta aaatcaaatt atcttcaatc ataatcaagt ttgattttat
     1441 ttctctgcta tcacttgtat ctaaattatc agagtattta gatacaaata gcatatatga
     1501 aaacagaaga aaacctgcta tatttaatac aataaaaagt aatgaaatca agatacttga
     1561 acctataaat cgcctcaata tgtactttac actatccaaa attaaatcac tcctcttgat
     1621 ttcttttatt ctaatatcta aaattaatta atcatcaact tatatccaag acctcttact
     1681 gtaataagat gtttaggtgt agatggagtt ttttctatct tctctctaac ccttctaaca
     1741 tgaaccataa gggtattttc atatccatac atatcatctc cccaaatggc ttgacatagt
     1801 gaatcattag taacaattct ccctttattt tcatacaact ttaaaagcaa cgaatgctct
     1861 ttagctgtta aagaaatctc ttgcccatct ttctcaacac atgcactatt taaattcaca
     1921 acaacagaat ctcccagttt aaatactggc aactcctctt cttctatagg cacatataca
     1981 cgatttaata tacccacaag ccttaaagta agttcctttg gtaaaaatgg ctttactata
     2041 taatcgtcag cccctaagcc caaaccaatc aatctatctt catcttcacc tcttgcagag
     2101 agaaaaatca ctggtatttt agatgtctct ctaatttttc tcataataga aaaaccatct
     2161 ccatctggca atacaacatc taaaattgca caatctggct ttacatttct aaatacccta
     2221 acagcttcct cataacttga tgctaaaaat actctactaa acccctcttt tctcaggatt
     2281 tcatctatca tttttaataa ttccttgtgg tcatcaacca caagtatttt tttatctttt
     2341 attgactcca taatcatcac cctcctttag tataccatat acccattttc acaactttgc
     2401 ctaaatagac ttttaaggtt attgtaaggt aaatttcagc taattgaaat gtaaccaagt
     2461 tattatactg atataagtta aaagaatcaa taagcacaga ttaaaaaagg ggatgaaaca
     2521 tatggaaatg ataattagaa cacaaagact ttcaaaggaa tacaataaaa tatttagagt
     2581 aaaggatata gacctaagag ttccacaagg agctgtatat ggttttttgg gtcctaatgg
     2641 agctggaaaa tctaccactc ttaaaatgct tcttggactt gctaaaccca cacaaggaaa
     2701 tattaatatt ttaggtaaag agttaaatga aaaaaataga atatcaattt taaaagatat
     2761 aggttctttg atagaatctc catcatacta tggtcatctt acagggcttg aaaacatgac
     2821 cataatgcaa agactcttag atttacctaa aaaaaatgta aatgaagcat taaaaattgt
     2881 aaggttagaa aatcaaaaaa ataaaaaagt tagtcaatat tctttaggta tgaagcaacg
     2941 tcttggcatt gctatggcaa taatgaagtt tcccaaatta ttaatacttg atgaacctac
     3001 aaatggactc gacccagcag ggattgagga aattagagaa ttaataaaat ctctaccaga
     3061 aaaatacggg atgactgttc taatctctag ccatctttta agtgaaattg accaaattgc
     3121 cacatcaata ggaataataa atcatggcga actggttttt caagatagca taaaagaact
     3181 tcataataga ggtcaaagtc agattgctat caaaactaag aatgttgtat ctgcacaaaa
     3241 actattaaat actaaaggat atatgtcact tatacaagat gggtacttga ctattgaaaa
     3301 tttaaaagac tcagatgtcg ctaaaataaa cggtatgctt gtccattcaa atatagatgt
     3361 atttagaata gaagaacata aaaaaagctt ggaagatata ttcttagaac ttactggtaa
     3421 ggcggtgact ttataatgaa ataccttggt ctagaatttt ataaacttaa aagaaagaag
     3481 attattctga tgaccttttt atttgtagct gttgaaataa tgtggtgtat cataaattca
     3541 aatagagcta ttacacgtaa tccagatatg ttaggtggat ttgaatattc ctatatgctt
     3601 atgagttttg caagtttaaa tggtctattc tttcctatct taatatcaat aattacatca
     3661 cgtataagcg atatagaaca taaaggagat acatggaagc ttttaaaatc ttctgtgaca
     3721 tctttaaata gtatttattt atctaaattt ttatgttctg ctattttggt atctatacct
     3781 gtattgatgc aagtgttatc tattgtgttg tttggacatt ttagaggggt tattgagtca
     3841 atttctgtat ctttactttt aaaatacaca ttaggaacaa ttcttgtaag tattgctatc
     3901 attgcactac acctatggat tgcaactgta attccaaatc aaatgattgc aattacattt
     3961 ggcatgattg gtagttttat aggtttgaca tcaggtttgt tttatcaagg tattcgtaga
     4021 ttgtttatat ggtcttatta cctagagtta tcacctttaa gttatgctta tgataatgtt
     4081 ttaggttcat ctgtctatag aattgatatg aatttttcta ttacgatttt agttttctta
     4141 attggaatgc taatttatta tattggaaga aatcatttat taaaaaaaga agtataggag
     4201 ggatttaaat gttaaggaag tcagttttgg gagaaattct aaagttaaaa aattctttta
     4261 tatggtatgt attattagct ttgccactta taagtgtgtt gattggttct ggtaattttt
     4321 atctaaatca aggcatactc aaaaaagaat ggtacagctt atggactcaa gttagtcttt
     4381 tttatgggga atttttcttt cctatcttaa tcgcaatctt ttgtgcatat atttgtaggc
     4441 ttgaacatat gaatcataat tggaataatg taatgacact gccagttaat ttaaaaaata
     4501 tctttttatc taaacttaca gtagtttcaa tacttacagc tattacacaa gttttctttg
     4561 ttatctttta tatagttgca ggaaatatgt ttggtttttc tggtagtgta cctaaagaat
     4621 tgactggttg gattgctaaa ggttggatta tttctatttc aatagcttct atacaattat
     4681 acatgtctat aaagattaga agttttgcaa ctcctattgg tattagtctt tgcctttctc
     4741 tatttggtat gggattaata gtagcaaaac ctgctgttgg tatatttttc ccttattcta
     4801 tgttaggtag tgctatgggg gttataaagc aatctgcttt aaatgttaat gacactatag
     4861 ttacaatatg tgttgcattt attactacta tagtattttc tgaaattgcc aatagaaatt
     4921 ttagaaagaa tgatgttatt tcttaatggt aaatgctaga tattttgggg tttgaaattt
     4981 atattctttt tagttgaaat ctatatccat tttatttaaa aatatatatc ttttatttga
     5041 attttatatg ttttatctac tcgctatata atagatatac tcctaaaatt aaaaaatata
     5101 taataatgtt attatttaaa attattatgt attatattaa aacttaatgc aaaaacaatt
     5161 tttatattat ataatgaaac ttaattgaat ataggtaaaa aatcattcaa tatat
//
LOCUS       DAEPKC010000160         5030 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.163, whole genome shotgun sequence.
ACCESSION   DAEPKC010000160 DAEPKC010000000
VERSION     DAEPKC010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5030)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5030)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5030
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.163"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            189..1496
                     /locus_tag="KR294_003572"
     CDS             189..1496
                     /locus_tag="KR294_003572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241616.1"
                     /translation="MKEIADAITSEYLSYGINEDISIYEGRFCIYLDKKYRCNGKIYY
                     KMTPPISISFKADIGCVEEIDNEDDNLALDYDNAILEVHGYKIISITINTLSEFSVEG
                     YINDDCIKSKNSYVEYVDFNIINLDKIPGKLIKYNDKVYAGRIEFDINDYVVTIDKRY
                     DYRKELKSELKSKSGAIITHIGRIRRKDGRIFRTNNTINLLDRISTALSFMCGRYVGF
                     CLAKGYRSGNEVYRIWNENQISPFRYVPTWSDTLSNYYNMEKYISLMCKKLEDFYYGS
                     AIKSVVDWYIESLGSATMENNIISVQIALETLSYVILVEQNKILTDEVFDCNLASKNI
                     RLLLDTCKIPYGKHELNIFDNIIKNKFDDGVDLVIYLRNSIVHPSRKTHRAVLEVEDI
                     WNIISIGTRYIELVLLFILGYRGEYSNRLVERCYGEVEVVPWN"
     misc_binding    1582..1844
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            1970..2773
                     /locus_tag="KR294_003573"
     CDS             1970..2773
                     /locus_tag="KR294_003573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HBH0241617.1"
                     /translation="MKNILKKVGIFTIMLGLLGGVVGCSKPDNEKDKDASKESKKEVV
                     VGFDNTFVPMGFLDEKGDTVGFDVDLAKETFKRLGMEVKFQPIDWSMKETELNDSKTV
                     DVLWNGYSITDERKKIVSYTEPYLQNKQIIVTLSDSKINSKADLKDKEVGTQQGSTAL
                     DAVEKDKDFMNSLKGGAPVLYDTYDKALRDLEIGRTSAVVGDEVLIRYYMGQKGEDKY
                     KVLKDDFGLEDYVVATSKENPELCEKINETLKEMKKDGTFDKIYDKWFK"
     gene            2811..3422
                     /locus_tag="KR294_003574"
     CDS             2811..3422
                     /locus_tag="KR294_003574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBH0241618.1"
                     /translation="MLQGLEIVIAMFCITLIVSIPLGIGVAFLRLSKNKLVSGITQCY
                     ILIMRGTPLLLQMIVIFYGLPLLGIVFDRFTAGVVAFFLNYAAYFAEIFRGGIQSIDR
                     GQYEASKVLGFDKFTMYKRVIFPQVFKRILAPISNEVITLVKDTSLVYILGLNDILRI
                     SQIAMNREASLLPLFEAGAIYLIFVAILTKGFELLEKKYSYYR"
     gene            3454..4125
                     /locus_tag="KR294_003575"
     CDS             3454..4125
                     /locus_tag="KR294_003575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBH0241619.1"
                     /translation="MLKIKNLNKSFKKNRVLKDISFELEEGQIGVLLGKSGAGKTTIL
                     RCINGLEEFDSGEIIIDNEVIKNKRDMAKIRGKIGMVFQNFNLFPHMTVLENIIESPV
                     NVFKVPRKEAEERARELLRLVDLEDKLNSYPFELSGGQQQRVAIARSCALMPKVLCFD
                     EPTSALDIDTIQRVVNIMNRLKDKGMTILIITHDVVFSNNVADKIISIKDGIVENVQI
                     KEKIV"
     gene            4423..4785
                     /locus_tag="KR294_003576"
     CDS             4423..4785
                     /locus_tag="KR294_003576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HBH0241620.1"
                     /translation="MIKLYGYTKCSTVKKAKNWLKENNLEFEDIDMVQNPPSKEELKS
                     IYKTSGYDIKKFFNTSGMKYRELGLKDIVKTESDDKLLEILVSDGMLIKRPLLLDGKN
                     VLLGFKEDVWKSTLLKED"
BASE COUNT         2029 a          455 c          881 g         1665 t
ORIGIN      
        1 ataactaaat ctaaacggaa tacataatgt attaaataaa tgatgatact aaaatgatac
       61 tatttttata gaaatttatt gaggtatata attaatgaaa ataatatatt aaattatata
      121 aattaaatta tataaattaa attatataat atattgagtt ttacataaaa gcaaaggtgg
      181 gaataaaaat gaaagaaatt gctgatgcta taacatcaga gtatttaagc tatggtatca
      241 atgaagatat tagtatctat gaaggtagat tttgcatata tttagataaa aaatatagat
      301 gtaatgggaa aatttattat aaaatgacac ctccaatatc tataagtttt aaagcagaca
      361 taggttgtgt tgaagagata gacaatgaag atgacaattt agctttagat tatgataatg
      421 ctattcttga agttcatgga tataaaatta tttctataac aataaatact ttaagtgaat
      481 ttagtgtaga aggttatatc aatgatgact gcataaaatc taagaactcc tatgttgaat
      541 atgtagattt taatataata aacttagata aaatacctgg aaaactcatt aaatacaatg
      601 ataaggtata cgcaggtaga attgaatttg atataaatga ttatgttgta actatagaca
      661 agcgatatga ttatagaaaa gaattaaaat cagaattaaa gtctaaatct ggagcaataa
      721 taactcatat aggtaggatt agaagaaaag atggtagaat ttttagaaca aataatacaa
      781 taaatctttt agataggata tcaacagctt tgagttttat gtgtggaaga tatgtagggt
      841 tttgtttggc caaagggtat agaagtggta atgaagttta tagaatatgg aatgaaaatc
      901 aaatatctcc ttttagatat gtaccaacat ggtcagatac actttcaaat tattataata
      961 tggaaaaata tataagcctt atgtgtaaaa agctagaaga tttttattat ggttctgcta
     1021 taaagagtgt tgttgattgg tacatagaat ctcttggaag tgctaccatg gaaaacaata
     1081 taatatctgt acaaattgca cttgaaactt tgtcatatgt aattctagtg gaacaaaata
     1141 agatacttac agatgaagta tttgactgta atttggcatc taaaaatata agactcttac
     1201 ttgatacatg taagatacca tatggtaaac atgaattaaa tatatttgat aatataataa
     1261 aaaataaatt tgatgatgga gtggatttag ttatttattt aagaaatagc atagttcatc
     1321 caagtagaaa gactcataga gctgtgttag aggttgaaga tatttggaat ataatttcaa
     1381 taggaacgag atatattgaa cttgttttac tctttatttt aggttataga ggagaatatt
     1441 caaacagatt agtagaaaga tgttatggtg aagtggaagt tgtaccttgg aactagattt
     1501 ttatatttat tttaaaatat atattgacat atattgcctt atgctataaa atcaatatca
     1561 taataataat tcagaataac attaaatgct aagaaaagaa atagtaaaag tagttaatct
     1621 taaacagaga gtttccgatt ggtgagagga gcaatagatt ttactttgaa cacatctttg
     1681 agcaggactc tgaaagagta gaaatacttt attaggagat ttccggaatc cttgcacccg
     1741 ttatagtgct agagtataat aattttattg tacttaaaga ggttagtgtc gtgaggcatt
     1801 aatgaacaga ggtggaacca cgagagttaa ctcccgtcct ctagcagaag ctagaggcgg
     1861 gagtttttta atataatttt ttaagcgcgc agagaattat attgcaatag atacactttt
     1921 taaaaaataa tcaaaatatt ttaaaaatta aaaggcgagg gagaatatta tgaaaaatat
     1981 attaaaaaaa gtaggaatat ttacaattat gttaggttta ttaggtggag ttgtaggttg
     2041 ttcaaaacca gataatgaaa aagataagga tgcttcaaag gaatctaaaa aagaagtagt
     2101 tgtagggttt gataatacgt ttgtaccaat gggattttta gatgaaaagg gagatacagt
     2161 aggatttgac gtagacttag ctaaagaaac atttaaaaga cttggaatgg aagttaagtt
     2221 tcagcctata gattggtcaa tgaaagaaac tgaattaaat gattcaaaaa ctgtagatgt
     2281 attatggaat ggatattcta taacagacga aagaaagaaa atagtatcat atacagaacc
     2341 atatttacaa aataagcaga taatagttac tctaagtgac tcaaaaataa attcaaaagc
     2401 tgatttaaaa gataaagaag ttggaacaca acaaggttca acagcacttg atgcagtgga
     2461 aaaggataaa gattttatga atagcttaaa aggtggagca ccagttcttt atgatactta
     2521 tgataaagca cttagagatt tagagatagg tagaactagt gcagttgttg gtgatgaagt
     2581 tttaattaga tactatatgg gacaaaaggg tgaagacaaa tacaaggtat taaaagacga
     2641 ttttggatta gaagattatg ttgtagcaac ttctaaagaa aatccagaac tttgtgagaa
     2701 aataaatgaa acattaaaag aaatgaaaaa agatggaact tttgacaaga tttatgataa
     2761 gtggtttaaa tagaagataa gttagctgtt aagaaggggg cactaaaggc atgttacaag
     2821 gtttagagat agttatagca atgttttgta taacattgat agtatcaatt ccattgggga
     2881 ttggagttgc atttttaaga ttatcaaaga ataaattagt aagtggtatt acacaatgtt
     2941 atatattgat aatgagaggt acacctttac ttttgcaaat gatagtcata ttttacggat
     3001 tacctctttt aggaattgta tttgacagat ttacagctgg agtagtagct ttcttcttaa
     3061 attatgcagc atattttgca gaaatattta gaggtggaat acagtcaatc gatagaggac
     3121 aatatgaagc ttcaaaagta ctaggatttg ataagtttac tatgtataag agagtaatct
     3181 ttccacaagt ttttaaaaga atactagcac ctatttcaaa tgaagtaatc acattagtaa
     3241 aagatacatc tttagtatat atattaggat taaatgatat tttaagaata tctcaaatag
     3301 caatgaacag ggaagcaagt ctgttaccat tatttgaggc aggagcgata tatcttatat
     3361 ttgtagctat acttactaag ggatttgaat tacttgaaaa aaaatattct tattatagat
     3421 aaagttacaa tattatagga ggaggttttt tatatgttga aaatcaaaaa cttaaataaa
     3481 tcatttaaaa aaaatagagt acttaaagat atttcttttg agttagaaga aggtcagatt
     3541 ggagttttac ttggtaagtc tggtgcagga aagaccacaa tattaaggtg tataaatggt
     3601 cttgaagaat ttgatagtgg agagattata atagataatg aggtaataaa aaataagaga
     3661 gatatggcaa aaatacgagg aaaaataggt atggtttttc aaaatttcaa cttatttcct
     3721 catatgacag tccttgaaaa tataattgaa tccccagtta atgtttttaa agttcctaga
     3781 aaagaggctg aagagagggc tagagaactt ttaagattag ttgatttaga agataaatta
     3841 aattcttatc catttgaatt gtcaggagga cagcaacaga gagttgctat agctaggtca
     3901 tgtgcattga tgccaaaagt cctttgtttt gatgaaccta cttctgcact tgatattgat
     3961 actattcaaa gagtagtcaa tataatgaac agacttaaag acaaaggtat gacaatatta
     4021 ataattacac atgatgttgt cttctcaaat aatgttgcag ataaaattat aagtataaaa
     4081 gatggtatag tagaaaatgt tcaaataaaa gaaaaaattg tttagagttt tataaatata
     4141 aactagggta gaattttata atataaataa agggcaagta aaatcaaata tactatgccc
     4201 ttttgttatc tcaaaattta atcttatatt ttatgtttaa gttacattat aatttataat
     4261 aaaaataaaa ggactattta aatatataat gtgaataatg tttaataatt tgaaatatga
     4321 taatttttta tgttgaaagc ttataatgat tatgatataa attggttata gtatacaatt
     4381 tatgggtata acaataaaaa attagaaagg aatttttata aaatgattaa attatatgga
     4441 tatacaaaat gctctactgt taaaaaagct aaaaattggc ttaaggaaaa taatttagaa
     4501 tttgaagata tagatatggt tcaaaaccct cctagtaaag aggagttaaa atcaatttat
     4561 aagactagtg gatatgatat aaagaaattt tttaatacaa gtggtatgaa atatagagaa
     4621 ttgggtctta aagatattgt aaaaactgaa tctgatgata aacttttaga aatattggta
     4681 agtgatggta tgcttattaa aagaccatta cttttggatg gtaaaaatgt attattgggt
     4741 tttaaagaag atgtatggaa aagtactttg ctaaaagaag attaggaaga gataggtgtg
     4801 ttgattaaaa ttattaatta atacacctat aaatttatgt attaaatcta atctttataa
     4861 atattaatta gcaaattcaa atcaaaaaaa ttcatatcaa caaacatatt acttcttatt
     4921 acaaattata tcatatgttt tatattaaaa tattataata ttacaacgaa ttgttacaaa
     4981 attacttatt attaaccatg aacatttgtt ttgtgctatc atatttatat
//
LOCUS       DAEPKC010000161         4874 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.164, whole genome shotgun sequence.
ACCESSION   DAEPKC010000161 DAEPKC010000000
VERSION     DAEPKC010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4874)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4874)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4874
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.164"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(325..1368)
                     /locus_tag="KR294_003577"
     CDS             complement(325..1368)
                     /locus_tag="KR294_003577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH/Band 7/PHB domain protein"
                     /protein_id="HBH0241621.1"
                     /translation="MGTKIVLSIVLIVVVVAISLTCIRVIKQSKVGIIMRLGKFQKVA
                     ETGVHFLIPFLDKMAYVIDLREIVIDFPPQPVITKDNVTMQIDTVVYYKVTDPVRYVF
                     EIANPIAAIENLTATTLRNIIGELDLDETLTSRDIINVKMRTILDEATDKWGIKVNRV
                     ELKNIMPPQDIQVAMEKQMRAERERREAILQAEGNKSAAILQAEGEKQSAILTAEAKK
                     EAMVRVAEGEKESAILVAEGEAEAIRQTAIAKAQGEAEMIKRTQMATAEGLKLVFSAM
                     KEADIDNNILALKSMEALEKMAEGKSTKLVLPSEAVNFLGTFKGIKEVMSDDNKEVLD
                     IKEVLNDNESLKK"
     gene            complement(1389..1835)
                     /locus_tag="KR294_003578"
     CDS             complement(1389..1835)
                     /locus_tag="KR294_003578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HBH0241622.1"
                     /translation="MKLIWLIVAVLFGIAEMLTPSLTLIWFSVGAVILIFLSSFIESI
                     FLQILIFAVISIAMLVVATKKIVKKDKGYKSNTNLQAMMSKKGIVTEEISPNNTGLVV
                     VEHETWTAISIDGEKIEKGSTVEVLKIEGVKLVVKKVDATVNVTNQ"
     gene            complement(2013..3593)
                     /locus_tag="KR294_003579"
     CDS             complement(2013..3593)
                     /locus_tag="KR294_003579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional ADP-dependent NAD(P)H-hydrate
                     dehydratase/NAD(P)H-hydrate epimerase"
                     /protein_id="HBH0241623.1"
                     /translation="MLIGTSKLSRNVDTACVEEVGIPMIVLMENAVISAMKNMDIDMY
                     NSYTVVCGVGNNGGDGLGIARHLNTYGKEVNVFLVGNLEKLSECSKINYNVLLNMGIN
                     IININKNDLSEKNYGEENEVDKIIKVEKQNIIKNKNLTIFKDRVSKSDVVVDAIFGTG
                     LKRDITGIFKEVIDIVNDNSKNTYSIDIPSGIDSDNGNVLGTCIRANKTISFEFYKRG
                     FLNYDTSALIGDVVVEKIGVPDFITRKYHDEEFITDKTFVKNNIRRRDKHGFKSDFGK
                     VSIVAGSKGFYGASFIATESAVKSGSGLVTLISSEDVQEKVSIRLTEAMTLNFEEERL
                     NKLLNSSDAIGFGPGMGDNSQTFDKLLKIVENSNCPIVLDADGLNVMKDRCYKFLEWK
                     NRFVITPHLGEMARLTGDSIGYIREHRVDVAKEFAQKYNLVVLLKGYQTVITDGKKTY
                     INPTGNSCMATGGMGDCLLGMITSFIGQGMDILEATVSGAYIHGYIGDKLSKAMYTVN
                     ATDLISNISLTMKELLDI"
     gene            4392..>4874
                     /locus_tag="KR294_003580"
     CDS             4392..>4874
                     /locus_tag="KR294_003580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0241624.1"
                     /translation="MSGIISVMTQSLILSIMALGVYITYKILDFPDMSADGSYTMGAS
                     IVAFSLTNGISPVVATLMAILCGCTAGLVTGILHIKFKISNLLSGILVMGMLYSINLR
                     IMGKSNIPLFSFKHLFNGEISPIVLALAFVFICKVLLDLFLKTGLGYTLKGVGDNSQM
                     I"
BASE COUNT         1558 a          833 c          493 g         1990 t
ORIGIN      
        1 taaactttta aattatttat tagttttctt agtattaatg tttatatttt tataaatata
       61 tattaataat ataaatagac taactaaaac catgcttatt tgctatatgt tttatattat
      121 attatataac actttttaca ttagtaaagg ataaattgta taaagattct gttaatttat
      181 ttttataatt tcatctttct aataaaaaca aagaagaaga cttaaaaatt tataagtcct
      241 cttcttttca acgtgcattt ttgtgctata tttaattaat tcgaccttta atttccatat
      301 ccttcctatg ataacaaaac tcttttattt ttttaatgat tcattatcat ttaaaacttc
      361 ttttatatca agtacttctt tgttatcatc actcataact tcctttattc ctttgaatgt
      421 tcctaggaaa ttaactgctt ctgaaggtaa aaccagtttt gttgacttac cttcagccat
      481 tttttcaaga gcttccatag attttaatgc tagaatatta ttgtctatat cagcctcttt
      541 cattgctgaa aaaactaatt ttaaaccttc tgctgttgcc atttgagttc tttttatcat
      601 ttcagcttca ccttgtgcct tagcaatagc tgtctgtctt atagcttcag cttcaccttc
      661 tgccactaat atagcagatt ctttttcacc ttctgctaca cgtaccatag cttctttttt
      721 ggcttctgct gttaatattg cagattgttt ttcaccttct gcttgaagta ttgcagctga
      781 cttattacct tctgcttgaa gtattgcctc tcttctttct ctttctgctc tcatttgttt
      841 ttccattgca acttgaatat cctgaggagg cattatattt tttaactcta ctctatttac
      901 ttttataccc catttatctg ttgcttcatc aaggatagtt ctcattttta catttattat
      961 atctcttgat gttaatgttt catctaaatc aagttcacca attatatttc ttagtgttgt
     1021 agctgttaaa ttttcaatag cagctattgg attagctatc tcaaacacat atctaactgg
     1081 gtctgtaact ttataatata caactgtatc aatctgcata gttacattat ctttagttat
     1141 aactggttga ggtggaaaat ctattacaat ttctctaagg tcaattacat atgccatttt
     1201 atctaaaaat ggtattaaga aatgtacacc tgtttcagct actttttgaa acttaccaag
     1261 tctcattatt atacctactt tagattgttt tataactctt atacaagtta aacttattgc
     1321 tacgactact actattaata caatacttaa aacaatttta gtacccatac tataaatcct
     1381 cctttattct attggtttgt cacattaact gtggcgtcta cttttttaac aactaatttt
     1441 accccttcaa tttttaatac ttctactgta gaaccttttt ctatcttttc accatctata
     1501 gaaatagccg tccatgtttc atgttcaact acaactagac ctgtgttatt tggagaaatc
     1561 tcttctgtaa caataccttt tttagacatc attgcttgta aattagtgtt agatttatag
     1621 cctttatctt tttttactat ttttttagta gctacgacta acattgctat agaaattact
     1681 gcaaatatta aaatttgtaa gaaaatactc tctataaagc tacttaaaaa tataagtatt
     1741 acagctccta cactaaacca tatcaatgtt aagcttggtg ttaacatttc tgctattcca
     1801 aataagactg ctactatcaa ccatattaac ttcatactat ctaccctctt ttcatatgaa
     1861 ttataaaacc ctatataaat tatatgttta tacaatgttt ttgaatataa atttaaatta
     1921 caaaacaata aaataaatta attaattaat taatagtatt atatcaacat actttgttaa
     1981 atttgttaca aagtagtatc aaatatcacc aattatatat ccaacaactc tttcattgtt
     2041 aatgaaatgt tacttattaa atccgtagca tttaccgtat acattgcttt gctcagttta
     2101 tctcctatat agccatgtat atatgctcca ctaactgtag cttccaatat atccatacct
     2161 tgacctataa atgaagtaat cattccaagc aaacaatcac ccattccacc agttgccata
     2221 cagctatttc ctgtaggatt tatatatgtt tttttaccat ctgttatgac agtttgataa
     2281 ccttttaaaa gcaccaccag attatatttt tgagcaaatt cttttgcaac atctactcta
     2341 tgttctctta tatacccaat tgaatctcct gtcaacctgg ccatttctcc caaatgaggt
     2401 gtaattacaa atctattttt ccattctaaa aacttataac atctgtcctt cataacgttc
     2461 aatccatctg catctaatac tattgggcaa ttagaatttt ctactatctt aagtaattta
     2521 tcaaatgttt gactattatc tcccatacct ggaccaaaac caattgcatc actagaatta
     2581 agtaatttat ttaatctttc ttcttcaaaa tttaaagtca ttgcttctgt aagtctaata
     2641 gatacctttt cttgcacatc ttcactacta attaatgtta caagtccact cccactctta
     2701 acagcagatt cagttgctat gaaacttgca ccataaaatc cttttgaacc tgcaactata
     2761 gatacttttc caaaatcact tttaaaacca tgcttatctc ttcttctaat attatttttt
     2821 acaaaagtct tatcagttat gaactcttca tcatggtatt ttcttgtaat aaaatctgga
     2881 acacctatct tttctacaac tacatcacct ataagtgcgc tagtgtcata gtttagaaaa
     2941 cctcttttat aaaactcaaa gctaatcgtt ttgtttgctc taatacaagt tcctaataca
     3001 tttccattat cgctatctat acctgaagga atatctatag aatacgtatt tttgctatta
     3061 tcgtttacta tgtcaataac ttctttaaaa ataccagtta tatcacgttt taatccagtc
     3121 ccaaatatag catctactac aacatcactt ttagatactc tatctttaaa aattgttaaa
     3181 tttttatttt ttataatatt ttgtttctca actttaataa ttttatctac ttcattttcc
     3241 tctccataat ttttttcact taaatcattt ttattaatat ttataatatt aattcccata
     3301 tttaaaagta cattgtaatt tattttagag cattcactta gtttttcaag attacctact
     3361 aaaaatacgt ttacttcttt tccatatgta tttagatgtc ttgctattcc aagaccatct
     3421 cctccattat ttccaacacc acatacaact gtataactat tatacatgtc tatatccata
     3481 tttttcattg cagatataac cgcattttcc atcaatacaa tcattggaat ccctacttct
     3541 tctacacatg cagtatcaac atttctgctt aatttagatg tacctattag cataaattat
     3601 cactcctata aagttaaaga cttcttaaat acttaccaaa aatatctatt gaaatctttt
     3661 taatcccata aatatcataa ataaaatcac taaaactaag agttttgaaa taatttaaaa
     3721 taacaaaaaa ttttgaatta aaacaattat ttaatttatt ataccatata atttaagtta
     3781 ttatgttgat ttaaaaccta tttacactaa ttatctaaat atctctttat ttttataatc
     3841 ttttatgact tatttatatt tttcattttt ataaaaaaac aataattaag aatataacta
     3901 tattctacat gtaaaaattt ttttatttaa actcaatttt ctgataattt gataattttt
     3961 caaaatttat agttgacttt tattttttac tgtattaaac taattactat acaaaacaga
     4021 aaacaaaatt ttcaaaatta ttaaattaaa aggagaggta aatatgaaga ctttattaaa
     4081 caaacaagta cgatttttta gtagccaatt tagttagggt ttgtacctaa gttaagacaa
     4141 attgtcataa catagataca agccccttag gattatgatt tttaaggatt gtatctatgt
     4201 tggctatagt aattgttgtt aaagttttta ttttatcatc ataatataga gccacatgga
     4261 ttatactgtg tggcttattc gaatttttgc catacagtta tatatactgt gtggtttttt
     4321 tatatcaaaa tcatttttta aaaccaaatt ttaaaaacca tttaaaatat tttcaaaggg
     4381 gtgttttatt tatgtcaggt attatatctg taatgacgca aagtttaatt ttatcgatta
     4441 tggcactggg ggtttatata acttacaaaa tcttagattt tccagatatg tctgctgatg
     4501 gtagctatac aatgggtgct tctattgtag cattttctct tactaatggt atttctcctg
     4561 tagtagcaac tttaatggct atcttatgtg gttgtactgc tggtcttgtt acagggattc
     4621 ttcacattaa gtttaagata tctaatttac tttctggtat tttagttatg ggaatgctat
     4681 actctatcaa tttaagaata atgggaaaat caaatattcc tctatttagc tttaaacact
     4741 tattcaatgg ggaaatatct cctatagttt tagccttagc ttttgtattc atctgtaaag
     4801 tccttttaga tttattccta aaaacaggtc ttggatacac tttaaaaggt gttggtgata
     4861 actctcaaat gatt
//
LOCUS       DAEPKC010000162         4873 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.165, whole genome shotgun sequence.
ACCESSION   DAEPKC010000162 DAEPKC010000000
VERSION     DAEPKC010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4873)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4873)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4873
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.165"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(<1..522)
                     /locus_tag="KR294_003581"
     CDS             complement(<1..522)
                     /locus_tag="KR294_003581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HBH0241625.1"
                     /translation="MIKETHERGGYIFALLILPFINNLYLVKYDIAYKIVLIIIYIYF
                     AYLGSLFPDIDMRGSYISKKFMLIYKLFGSRFRHRGFTHSLIALLLIYSFFKSLTIFT
                     NNNIVFSCLSSGFIIGYLSHLCLDLITKEGIELFYPITINISLLPIKTNSKTEKFISK
                     LLNFIVIFLIGYQF"
     gene            complement(635..1309)
                     /locus_tag="KR294_003582"
     CDS             complement(635..1309)
                     /locus_tag="KR294_003582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HBH0241626.1"
                     /translation="MSLFIISQCITSFAFTPENNKFKVKPLPYAYDALEPYIDKETMK
                     LHHDKHYQAYVDKLNAALEKYPELYNYSLCELLQNLDSLPKDIATTVRNNAGGAYNHK
                     FFFDIMTPEKTIPSESLKEAIDRDFGSFEKFKQEFQKSALDVFGSGWAWLVATKDGKL
                     SIMTTPNQDSPVSKNLTPIIGLDVWEHAYYLKYQNRRNEYIDNWFNVVNWNGALENYK
                     NLKSQD"
     gene            1512..3386
                     /gene="asnB"
                     /locus_tag="KR294_003583"
     CDS             1512..3386
                     /gene="asnB"
                     /locus_tag="KR294_003583"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HBH0241627.1"
                     /translation="MDGNISIYYKGDISKKEDIKFKIKESVNNTRLSSRIEYKDEEKT
                     FDFERFNVIDAIYGNKPFEKDGKVIVFNGNIYNYHEIKEELIKKGHNFTTNDDIEVLL
                     ASYIEFGKNCVHKIKGMFNFIIYDRENESIFGARDLFGIKPLYYINKENAIIFSSEYK
                     FLLEYMKNLNINERSLQSYFSFQYVLPEDTMIQGIRLIPAGHYFRVENGILSLKRYNK
                     LEFRSSTKFFYTKNHLGNRDVNEDDIRNIVVDSIVTHMEEEKEIGTFLSGGIDSSIIT
                     TVASQINPNIKSFSAGFSVKGYSELEVAKKTADKLGIENIQINITQDEYIKSLPNVIY
                     SLDDPIADPSEVGLYFLIKEAGKHVKVALSGEGADELFGGYNIYKEYSTMKSVVNSPT
                     YIKSILGRVSELMPNIKGRNYLYRATTPLEKRYIGNAKVFENSEVKRFFFKYKEKNIY
                     EYLLSNLYRDAQKNNYDYISKMQHIDVNTWLQGDILQKISKLSTAEQVELRVPFLYKD
                     VFDVAKNLRMEQKINKNNTKVLLREAFREIVPEHVVQRKKLGFPTPIRVWLKDSLGDI
                     VKETIYNSNVDEFIDKKYAIKLLDTHLKGHRDNSRKIWTIFTFCLWHQLFIEHKNVEY
                     "
     gene            complement(3478..>4873)
                     /locus_tag="KR294_003584"
     CDS             complement(3478..>4873)
                     /locus_tag="KR294_003584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HBH0241628.1"
                     /translation="STEPLIEFISDTTYKNKRSSYIKEVYFTRYIGVDDSIDKYIEKI
                     KNIDTYFFNNPTIPYIRLNNLKINFDKEQTDKMLKIFNIYNSSKFNSWDLYNIDFPCK
                     IENDTLNWTKKIAFKNTLDLFSTSMPNCTSSIIKNFAVKLLCWIDYFLPKLFYNKVKT
                     TISPKIVYFGNIKRQELFFLYFLSQLGCDILYINPNKDILDLYPECSKFSTLFELSRK
                     TPNILEIPFERHITNINYSENTNKTSPTTNKPNSKNTLNNTNLTSKKIVQDEEVELSY
                     EDLAKLSASVVMIVVCNNENKPFKSGSGVVINNEGYILTNLHVVNDGYSFLVRFENDD
                     KVYTSYQIIKYHSDYDLAVIKVDRKCKPIPVKVSKKPVRGQKIVAIGSPLGLFNTVSD
                     GIISAFRDFETVQMIQFTAPISSGSSGGALLDMFGNLLGLISAGYDDGQNLNLAVESN
                     LVKIFANNFIEIVN"
BASE COUNT         1883 a          588 c          710 g         1692 t
ORIGIN      
        1 aaattgatat ccaatcaaaa aaataactat gaaatttaat agcttagata tgaatttttc
       61 tgtttttgag ttagttttta taggtagtaa agaaatgttt atagtaatgg gataaaacaa
      121 ttcaatacct tctttagtaa taaggtcaag acacaagtga gatagatatc ctattataaa
      181 cccactggac aaacatgaga aaactatatt attgttagtg aagattgtca gagatttaaa
      241 aaaactataa ataagtaata aggcaattag actgtgagta aaccctctat gtctaaacct
      301 acttccaaat aatttgtata ttaacataaa ttttttactt atgtaagaac ctctcatatc
      361 tatatctgga aataaagaac ctaaatatgc aaaataaata taaattataa ttaatactat
      421 tttatatgca atatcgtatt taactaggta cagattgttt ataaagggga gtatcaaaag
      481 tgcgaatata taacctcccc tttcatgtgt ttcttttatc atataaaaat cctcctgaat
      541 cgtcactata aacattatat tggtaaattt agactatctt ttattatatt atatagcaaa
      601 cataagtttt tttcaaaagg attttaatat ttaattaatc ttgagatttt aaatttttgt
      661 aattttctaa agcaccattc caatttacta cattaaacca gttgtcaatg tattcatttc
      721 ttctattttg atattttaaa tagtaagcat gctcccaaac atcaagtcct attataggag
      781 ttaggttttt acttacaggg ctatcctgat ttggagtagt cataatagat aatttcccat
      841 ctttagtagc tacaagccaa gcccaaccag aaccaaagac atctaaagca gatttttgga
      901 actcttgctt aaatttttca aaagaaccaa agtctctatc aatagcttct tttaaagatt
      961 cagaaggtat ggttttttct ggcgtcatta tatcaaaaaa gaatttatga ttataagctc
     1021 cacctgcatt atttcttaca gttgtagcaa tatctttagg taaagaatct aaattttgca
     1081 ataattcaca taaagaataa ttataaagct caggatattt ttcaagagca gcatttaatt
     1141 tatcaacata agcttgataa tgcttatcat gatgcagttt cattgtttct ttatctatat
     1201 aaggttcaag tgcatcatat gcataaggta atggtttaac cttaaatttg ttattttcag
     1261 gtgtaaaagc aaatgaagtt atgcactgtg agattataaa taaagacata ataactggta
     1321 ttaatatttt tttcttcata aaaatcacct cctaatatag tatttctaga aataaaaaaa
     1381 atatgaaata ttaacagata atttataaga atttaatagc aatttcattt taaattgaat
     1441 aagttttaaa gccaaagaca aaactatgaa atatagaata agactaaagg acagaaagga
     1501 attttgatta tatggacggc aatatttcaa tttattataa aggtgatata tctaaaaaag
     1561 aagatattaa atttaaaata aaagaatctg taaataatac aagactttct agtagaatag
     1621 agtataagga tgaggaaaaa acttttgatt ttgaaagatt taatgtaatt gatgctattt
     1681 atggaaataa accatttgaa aaagatggaa aagttattgt ttttaatgga aatatatata
     1741 actatcatga aataaaagaa gaattaatta aaaaaggaca caattttact acaaatgatg
     1801 atattgaagt cttattggca tcttatatag aatttggtaa gaattgtgta cataagatta
     1861 aaggaatgtt caactttata atctatgata gagaaaatga aagtatattt ggagcaagag
     1921 atttatttgg gataaaacca ctctattata taaataagga aaatgcaata attttttcct
     1981 cagagtataa gtttttactt gaatatatga aaaatttaaa tataaatgaa agaagcttac
     2041 aaagttattt ttcatttcaa tatgtacttc ctgaagatac tatgatacaa ggaataaggc
     2101 tgataccagc aggtcactat tttagggtag aaaatggtat actatcttta aagagatata
     2161 ataaacttga gtttagaagt agtacaaaat ttttttatac taaaaatcac ttaggcaata
     2221 gagatgtgaa cgaggatgat ataagaaata tagtagtaga ttcaatagta actcatatgg
     2281 aagaggagaa agaaattgga acatttctgt ctggtggaat agattcatct attataacta
     2341 ctgtggcttc acaaattaat ccaaatataa aatctttttc tgcaggcttt agtgtcaaag
     2401 gatatagtga attagaagta gcaaagaaaa cagctgataa gttaggtata gaaaatatcc
     2461 agattaatat aacacaagat gaatatataa aatcattacc gaatgtaatt tattctttgg
     2521 atgaccctat agcagaccct tcagaagtag gtctttattt cttaattaaa gaggcaggta
     2581 aacatgttaa agtagcattg tctggagaag gagcagatga attatttgga ggatataata
     2641 tatataaaga gtatagtact atgaaatcag ttgtcaattc acctacttat attaaaagta
     2701 tattaggaag agtttcagaa cttatgccaa acataaaagg aagaaattat ctttatagag
     2761 ctacaacacc attagaaaaa agatatatag gaaatgcaaa agtttttgaa aacagcgaag
     2821 taaaaagatt cttttttaag tataaggaaa agaatatata tgaatacctg ttgtctaatt
     2881 tgtatagaga tgcacaaaaa aataattacg attatataag taaaatgcaa catatagatg
     2941 tgaatacatg gcttcaaggc gatatacttc aaaaaattag caaactttct acagctgagc
     3001 aggttgaact tagagtacca tttttatata aagatgtatt tgatgtagca aaaaatttaa
     3061 gaatggagca aaaaataaat aagaataata caaaagtttt acttagagag gcgtttagag
     3121 aaatagtccc agaacatgtt gttcaaagga aaaaattagg atttccaact ccaataagag
     3181 tttggttaaa agattctcta ggggatattg taaaggaaac tatttataat tcaaatgtag
     3241 atgaatttat agataaaaaa tatgcaataa aacttttaga tacgcatctt aaaggtcata
     3301 gagataattc gagaaaaata tggactatat ttacattttg tctatggcat caattattta
     3361 ttgagcataa aaatgtcgag tattaatact tttttcaata ttaatcagag ggcaaaagca
     3421 tgcaatgttt tcaccctcct gattattatg gaataggata agtagaattt tgattgatta
     3481 gtttactatc tcaataaaat tattggcaaa tattttgaca agattacttt caacagctaa
     3541 atttaagttt tgtccatcat catatccagc ggaaatcaat cctagtaagt ttccaaacat
     3601 atctaaaaga gctcctcctg aactaccact agagattgga gctgtaaatt gtatcatttg
     3661 aaccgtttca aaatcacgaa aagctgaaat aattccatct gaaactgtat taaaaagacc
     3721 tagagggctt ccaattgcaa ctattttttg acctctcaca ggttttttac tgactttaac
     3781 aggtattggc ttgcattttc tatcaacctt tatcacagct aaatcataat ctgaatggta
     3841 ttttataatt tggtaagatg tataaacttt atcatcattt tcaaatctaa ctaaaaatga
     3901 atacccatca ttgactacat gaagattcgt aagtatataa ccttcattat ttattactac
     3961 tccagaaccg ctcttaaacg gtttattttc gttattgcac acaacaatca taacaacaga
     4021 agctgataac tttgcaaggt cttcataaga aagttctact tcctcatctt gtacaatttt
     4081 tttagatgtt agatttgtgt tattaagtgt atttttagag ttaggtttat tcgtagtagg
     4141 agaagtctta ttggtatttt cactgtaatt tatatttgta atatgccttt caaaaggtat
     4201 ttctaatata tttggagtct tcctagaaag ttcaaataga gtagaaaatt ttgaacattc
     4261 aggatataaa tcaagaatat ctttatttgg atttatatat aaaatatcac acccaagttg
     4321 tgataaaaaa tataagaaaa aaagttcttg ccttttaata tttccaaagt atactatctt
     4381 tggtgaaata gtagtcttca ccttgttata aaataattta ggtagaaaat agtctatcca
     4441 acacaaaagt ttaactgcaa agtttttgat gatagaggat gtacaatttg gcatacttgt
     4501 ggaaaataaa tctaaagtat ttttaaatgc aatcttttta gtccaattta aggtgtcatt
     4561 ttctatttta catggaaagt cgatattata taaatcccaa ctgttaaact tagaactatt
     4621 ataaatatta aaaattttaa gcatcttatc tgtttgttct ttgtcaaaat ttatttttag
     4681 attgtttaat ctaatatagg gaattgtagg attattaaaa aaataagtat ctatattttt
     4741 aattttttct atgtatttat caattgaatc atcaacacct atatatcttg taaagtagac
     4801 ttctttaata tatgaagaac gcttattttt ataggtagta tcagatataa attcaattag
     4861 aggttcagta gac
//
LOCUS       DAEPKC010000163         4675 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.166, whole genome shotgun sequence.
ACCESSION   DAEPKC010000163 DAEPKC010000000
VERSION     DAEPKC010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4675)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4675)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4675
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.166"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            230..1369
                     /locus_tag="KR294_003585"
     CDS             230..1369
                     /locus_tag="KR294_003585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HBH0241629.1"
                     /translation="MVIKLTIEEYKNKYFTGNKIVLSINSFDNKELYYHETENILNLI
                     NEIDKLTSSKIFKIIEDKNDLALESYYSSVIEGAFSNRKIAKSIIRGKMKPSNKSEYM
                     IYNNHRALEYGLDNLDKLYSHKFIYDLHHILGENCLDSEEYEYRTEKVYVCDSKGEII
                     HIGLEPLKIYDFMSKLIDFMENSKVSNLIKSAIIHFYFVYVHPFSDGNGRTSRALSYL
                     YLIDKGYDTFKDFSISYMISKNRTKYYKAILDVENKGNNLTVFIEFMLKSIIQSINEM
                     RNMHDRKSLESILKEELFENDITLSATEEHILKYICNKDNYSMTLENYIKKNKSRYLK
                     AGIKEIELVDQLMEVFNNLEEIEILSKEKNIYKVNDKYLKMLDID"
     gene            1395..1583
                     /locus_tag="KR294_003586"
     CDS             1395..1583
                     /locus_tag="KR294_003586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241630.1"
                     /translation="MNNKKKAFLISGAINVISLIIVFSLFHYNIIENSTQNMIITVIL
                     IFIFEMIKIKIIEKYYKL"
     gene            2367..3923
                     /locus_tag="KR294_003587"
                     /pseudo
     CDS             2367..3923
                     /locus_tag="KR294_003587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860844.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein CwpV"
BASE COUNT         2050 a          488 c          789 g         1348 t
ORIGIN      
        1 gttaagacat tgtcgagata ttataatatg taactaatgt attataaata atagttgtaa
       61 acttcctgtg acatatattt taaatgctta ttcttaaatt tttgcattat ttattaaaat
      121 ttattatgct ttaacgctaa attgagtttg ataattataa aacaaataat caaaaatagt
      181 gtaaaaatta atactttttg ttaatattaa tagataaaga taatctaagg tggtgattaa
      241 actgacaata gaagaataca aaaacaaata ctttactgga aataaaatcg tactttctat
      301 aaatagtttt gataataaag aactatacta tcatgaaact gaaaatatat taaatttaat
      361 aaatgaaata gataaattaa catcaagtaa gatatttaaa ataatagaag ataaaaatga
      421 tttggcacta gagtcttatt attctagtgt aatagaaggt gctttttcaa atagaaagat
      481 tgcaaaatct ataattagag gaaagatgaa accaagtaat aaaagtgaat atatgattta
      541 caataatcat agagccttag aatatggatt agacaactta gataaattat atagtcacaa
      601 atttatatat gatttgcatc atatattggg cgaaaactgc ttggattcag aagaatatga
      661 gtatagaact gaaaaagtat atgtatgtga ttcaaaaggt gagattatac atatagggct
      721 tgaacctttg aagatatatg actttatgag taaattaata gattttatgg aaaatagcaa
      781 agtaagtaat ttaattaaaa gtgctataat tcatttttac tttgtatatg ttcatccttt
      841 tagtgatggt aatggaagaa catcaagagc cttatcatat ctatatttga ttgataaagg
      901 atatgatact ttcaaggatt tttcaatatc atatatgata tctaaaaaca gaactaagta
      961 ttataaggct atacttgatg tagaaaacaa aggaaataat ttaactgtat ttatagaatt
     1021 tatgctcaag tctataatac aatctattaa tgagatgcgt aatatgcatg atagaaaatc
     1081 tttagaaagt atattaaaag aggaattgtt tgaaaatgac ataactctat cagcaacaga
     1141 agaacatata ttaaaatata tttgcaataa agataactat tctatgacat tagaaaatta
     1201 tataaaaaag aataaaagta gatacttaaa ggctggaata aaggaaattg aattagttga
     1261 ccagttgatg gaagtgttta ataatcttga agagatagag attttgtcta aagaaaaaaa
     1321 tatatataaa gttaatgata agtacttaaa aatgcttgat atagactaat ttagataatc
     1381 tggagaggga atatatgaat aataagaaaa aggcattttt gatttctggg gctataaacg
     1441 taatttcatt aattattgtt ttttcattgt ttcattataa tattatagaa aatagtacac
     1501 aaaatatgat aataactgta atcttaattt ttatttttga aatgataaaa ataaaaatca
     1561 tagagaaata ctataaacta taaacaagaa atatcttttc taagagcata ttgtacaata
     1621 tgctcttaat ttagttatat agatttaata taaataatgt attttttgta gatgatttat
     1681 gtaagattta tgaccaattt gtgtatgatt tgtgttcttt aatcatgaca atattatatt
     1741 gtaaaaaata aatttaataa aaaatgactt ggaatttata ttctaggtct tttttatata
     1801 aaaatttaat aagtttcaaa tgttggtaac tttgacagta gaaaacgtct attgagataa
     1861 cgaggattct aattgagggg gagatatatt agcacttaaa gtagtatatg caacagatat
     1921 aatctttata aaagtaattt gaattaaaat gtaaatataa agaataatta aaaaaatatc
     1981 gcaattattt gtttttcata tggataaaat tggttattta atatataatt acaagtataa
     2041 ataataaaat ttatttgtaa aaagagtagc acttttaatt ctaaaggcta ctttttttat
     2101 acaaaaccct attttttata acaattcatt aacataaaaa tcaaacttac cttaaaatat
     2161 aaatttacaa atttttcaat caataagaaa atttctttat tccttacata atgactgcaa
     2221 tgtaacaaaa taattacaaa ttaattatga aatcattata gttagaaacc tctttaaaat
     2281 tagatattaa gtatccttta gaattagaac gggaacaaag ttaaaaaatt aagtaatatc
     2341 aaatggacaa gggggaagaa aataaaatga aaataccaaa gaagattgct gcaatgctta
     2401 cagttacaat gatagctgga agttcaacag caggcatagc tagtgcacaa actgtggcaa
     2461 caaatttaac agggcaagaa agatatgaaa ctgctgttaa aataagtcaa gatggatgga
     2521 aaaatgctga tgaggtagta atcgtaaacg actcatctat agcagatgct ctatctgcaa
     2581 caccatttgc aaaagcaaaa aatgctccaa tacttttaac aagtaaagat aaattaaatg
     2641 ataagacgaa agcagaaata caaagattaa aagctaaaaa agtatactta ataggtggaa
     2701 cttctgtatt aagtacaaat atagaaaaag aaataaaaga tttaaaaata tcttttgaga
     2761 gaatctctgg agctgagaga tatcaaacat ccttagaatt agcaaagaaa ttagatgcta
     2821 taagtgatgt taagaaaata gctgtagtta atggtgaaaa aggacttgca gatgctgtaa
     2881 gtgtaggagc accagctgca caaaacaata tgccagtaat acttgctgat tctaaaaatg
     2941 gaacagcagt tgcagacaaa tttataaagg atgctggaat aactcaatct tatgtagtag
     3001 gtggagagag ttcaatttct gaagctgtta aaaataaact accaaatagt acaagactag
     3061 gtggaacaga tagaaatgat acaaatgcaa aagtaataaa agaattttat aaaaagacag
     3121 atttaaaaaa tgcttatgta actaaagatg gtatgaataa acaagaccaa cttatagatg
     3181 cactagcagt aggtgtatta ggtgctaaaa atcaatcacc agtagtttta gttggaaaga
     3241 acttatcagc ttcacaaaaa tctctaatta actctaagag ttttgataag ataactaaag
     3301 ttggtgggaa tggtaatgag acagcattta atgaaatgaa gtcattacaa gaagtaaaaa
     3361 cagttgaagc taaaacaatt tctgaattaa aatcagctat agataaagct actgctaatg
     3421 atgttataaa cttcaaacca actagtgagg ttaaagaagc atttacaata caaactgata
     3481 aagcagtaac agtaaactta aatggtacat atacaaagac tgtgactatc aacatgccta
     3541 atggtgatgt aaataactat gcaaaagtgg atgatgtagt tatagatgat gtaaaagatg
     3601 gaacttttgt taattatgga aaaataacta acttaaaggt taatgataaa aatggagcca
     3661 agatagaaaa taattctaaa ggtgagattg gtagtttaac agtagcatct ggagcaagtc
     3721 aagtaaaagt gactaatggt ggtaagataa ctacagttac aaataattct aaagggacta
     3781 ctatagataa taaaggtaca ataagtagtg ttaagggaga taattctcca acaataagtg
     3841 gaaatagtcc aagttctaac tcttcaggag gaagttcatc aagtggaggt tcttcacatg
     3901 gaggaggaag ttcttcatca aaaccaagcg ataagtcaaa aacaaagaca aaagcagaag
     3961 aaaaaatagc agaggtaaca aaactagtag gaaaagtaac agcagataat ttagaagcat
     4021 caaaagtaac attaaaagca gcaactgatg caatagaaga agcaaggaaa gcagggtgga
     4081 cagaatcaga agttcaaagc tttaaaggat atggagatat agcaaaagta caaagtgaga
     4141 taactgaatt agaatcacag gctaaagaag cagcaaagac aaaagcagaa gaaaaaatag
     4201 cagaagtaac aaaactagta ggaaaagtaa cagcagataa tttagaagca tcaaaagtaa
     4261 cattaaaagc agcaactgat gcaatagaag aagcaaaggc agcaggatgg acagaatcag
     4321 aagttcaaag ttttgcagga tatgaagata tagcaacagt acaaggtgag atagctgcat
     4381 tagaatcatc acaggctaaa gaagaagcaa agacaaaagc agaagaaaaa atagcagaag
     4441 taacaaaact agtaggaaaa gtaacagcag aaaatttaga agcatcaaaa gtaacattaa
     4501 aagcggcaac tgatgcaata gaagaagcaa aggcagcagg atggacagaa tcagaaattc
     4561 aaagttttgt aggatatgaa gatatagcaa aagtacaaag tgagataact gaattagaat
     4621 cacaggctaa agaagcagca aagacaaaag cagaagaaaa aatagcagaa gtaac
//
LOCUS       DAEPKC010000164         4650 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.167, whole genome shotgun sequence.
ACCESSION   DAEPKC010000164 DAEPKC010000000
VERSION     DAEPKC010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4650)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4650)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4650
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.167"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..893
                     /locus_tag="KR294_003588"
     CDS             <1..893
                     /locus_tag="KR294_003588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBH0241631.1"
                     /translation="NPQSKLPRVEEISYREKIIIIHKIYSFMENYIKFPKENLPNRKV
                     MSDININDIESLAYKTREFWDLNSTPIVNMVSLLESKGIIISGMNVDRKGATIFTQKQ
                     RISKESKYLISLGNDKKSASIRNYTLACELGYIISSELRIPSKQFSEDEYACAFLLPK
                     ESFLKDLTHPEDLDYYVELKKKWIVPISAMIFRAYNLEKINYKKYNYLMNEMDKKGWL
                     IEEPLDKMKGSSPTYLKRAVELLIENKIMSVNSIVSSLEEFGINLYPEDLELLMGLKK
                     GLLSQEVNKKSKVIKFDGKK"
     gene            complement(1010..1978)
                     /locus_tag="KR294_003589"
     CDS             complement(1010..1978)
                     /locus_tag="KR294_003589"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HBH0241632.1"
                     /translation="MAIKPRKISIVGSGHVGSHCGFSLITQGVCDELFMIDIDESKSK
                     AQALDLADAVSYLPHKVHIEKGTFSDCKDSDIVVISVADSSEGPLRRQNTTRLDLLRP
                     TIGMIKSIVKPIVDSGFDGIFVVISNPVDVVTNYIWEKSGFPKNKVIGTGTALDSTRL
                     RRILSEETGIAQQSIQAYSMGEHGDSQMVPWSHVSIGGKPILDMIKDNPSTYSNLDLP
                     SIVEKNKKTGISIINGKDCTEFGIGTALVEIVKAILHNEKKVLPVSTLLEGQYNERNV
                     FAGVPCVIGKDGIEEIIEINMTEYEQNEFNKSCSVLREYIALSKTL"
     gene            2313..2501
                     /locus_tag="KR294_003590"
     CDS             2313..2501
                     /locus_tag="KR294_003590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241633.1"
                     /translation="MNYHTKEELVEALRVVSSSIINCGKGQKKFSEETSHHTRFKNII
                     EVMYISKSLIMDEISKRD"
     gene            2761..3960
                     /locus_tag="KR294_003591"
     CDS             2761..3960
                     /locus_tag="KR294_003591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanyl-tRNA editing protein AlaX-L"
                     /protein_id="HBH0241634.1"
                     /translation="MEKLYYTNQYIRDFTAEIIEIKEVENKYHVLLDKTAFFPGGGGQ
                     FGDLGKIESDDVINVYEDGKKIYHVLDKKPIKIHKVKCSIDWDRREDGMHQHFGQHVL
                     SGCFFKTFNANTTGFHLGNEYSTVDIEGNLEEDKIREIELFANEIIRQNIQVETLLPT
                     KKELKKIWLRRDLPNTDEEIRVIKIGDLDTNACCGVHPKSTGELRMIKIKKWEKHKSS
                     TRIEFLAGKRAVDEVLKRDIYLTKICRYLSCSEEDAINGIVNLNSKVEEALIKKRRLE
                     EVVSTYQVKEMIEKANKVGNISVIKKIYDDEDLKYVNKIANKIAEYENSIALLAVKFN
                     DKINLVFACSKNLKDINMGVLLKDAISLIDGKGGGSKVLAQGGGKNNGNLEATLDYAF
                     MKIEKTL"
     gene            4012..4515
                     /locus_tag="KR294_003592"
     CDS             4012..4515
                     /locus_tag="KR294_003592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH0241635.1"
                     /translation="MEQQKDYIELYENEELIEIREARMDDLDTIAKFNYNLAKETEGK
                     ELDMDVLTKGVKALLLDERKGKYHVYTVFDKVVAQIMYTYEWSDWRNGNFLWIQSVYV
                     DKEYRRKGIFNYLFNYIKNICDKDENIVGMRLYVEKENINAKATYESLNMYECDYNMY
                     EYEVIHS"
BASE COUNT         1871 a          451 c          795 g         1533 t
ORIGIN      
        1 ttaaccctca atctaaacta cctagagtag aagagatttc ttatagagaa aaaataatta
       61 taatacataa aatatattca tttatggaga attatattaa gtttccaaaa gaaaacttgc
      121 caaatagaaa agtaatgtca gatattaata taaatgatat agaatctctt gcatataaga
      181 ctagagagtt ttgggattta aatagtactc caatagtaaa tatggtaagt ttgttagagt
      241 ctaaagggat tataatatca ggtatgaatg tagatagaaa aggggcaact atctttactc
      301 aaaaacagag aattagtaaa gaatctaaat atctaatatc tctgggtaat gacaaaaagt
      361 cagcatcaat tagaaattat actttggcat gtgagcttgg atatataata tcaagtgaat
      421 taagaatacc aagtaagcaa ttttcagaag atgagtatgc ctgtgcattt ttattgccaa
      481 aagagagttt tttaaaagat ttgactcatc cagaagattt agattattat gtagaactaa
      541 agaaaaaatg gattgtacct atatctgcta tgatttttag agcatataat ctagaaaaga
      601 taaattacaa aaaatacaat tatcttatga atgaaatgga taaaaaaggc tggttgatag
      661 aagaaccact agacaaaatg aaaggttcaa gcccaacgta tttaaaaaga gcagttgaat
      721 tattgataga aaataaaata atgagtgtaa atagtatagt atcaagttta gaggaatttg
      781 gaataaatct ttatccagaa gacttagaat tattgatggg attgaaaaaa ggattgttat
      841 ctcaagaggt aaataaaaaa agtaaagtta taaaatttga tggtaaaaaa taggtttata
      901 ttttagtatt aaaattaaaa gcaggtacaa atgatttaaa cattaactta gttaaaagtc
      961 ttttcaataa gtcatttacc tgcttttagt gtaagaaaga atattgaatc taaagtgttt
     1021 ttgaaagtgc aatatattcc cttaaaacag aacaagattt attaaattcg ttttgctcat
     1081 attcagtcat attgatttca ataatttctt caataccatc ttttcctata acacatggaa
     1141 cacctgcaaa tacatttctt tcgttatatt gaccttctag taatgtagaa actggaagaa
     1201 cttttttctc attgtgtagt atagctttta caatttctac taaagcagta cctataccaa
     1261 attctgtaca atctttacca tttattatac ttattcctgt ttttttattt ttttcaacta
     1321 ttgatggtaa gtctaaattg ctataagtac ttgggttgtc ttttatcatg tctaagattg
     1381 gtttaccacc aattgaaaca tgagaccaag gaaccatttg agaatctcca tgttcaccca
     1441 tagaataagc ttgaattgat tgttgagcga ttccagtttc ttcagataaa atccttctaa
     1501 gtcttgttga atctaaagct gttccagttc caatgacttt gtttttagga aagccagatt
     1561 tttcccaaat ataatttgta actacatcaa caggattaga tatgactaca aatataccat
     1621 caaagccaga atcaactatg ggttttacta tagattttat cattccaata gttggtctta
     1681 gtaaatctaa tctagttgtg ttttgtctac gtaaaggccc ttctgaagag tctgcaacac
     1741 ttatcactac tatgtcagaa tctttacagt cagaaaaagt tcctttttct atatgtactt
     1801 tatgtggcag atatgaaact gcatcagcta aatctaaagc ttgagctttt gatttagatt
     1861 catctatatc aatcataaag agttcatcac aaactccttg agttattaaa ctaaatccac
     1921 aatgagaacc aacatgccct gaacctacaa tagatatttt tcttggcttt attgccattt
     1981 taaatcactc cccctaaaat aacgatacat tgaaaattat agatgttatt aaaagctgtt
     2041 tttggatatt ttaatattct attatttcag aaaatttatt taatatgatt ttatactaaa
     2101 atttttaaaa aagcaatgtt aatatactct ctattagtga atattaaagt attatatgta
     2161 tattaataat tattaaaata tgtaatgtca ctgatagtta gaatatttaa gtgctaaaag
     2221 atgtgtataa ataataatga tgtcagttta taatgatatt aaattgagat atactgtttc
     2281 tctaaattaa aaaataaagg agtaaatgtg ttatgaatta tcatacaaaa gaagaattgg
     2341 tggaagcact gagagtagta tcttcaagta ttattaattg tggaaaagga cagaagaaat
     2401 tttctgagga gacatctcat catacacgtt ttaagaatat tatagaagta atgtatattt
     2461 caaaatcatt aataatggat gaaattagta aaagagattg aagcttattt tgcaatttaa
     2521 catgttttaa tatacatttt attatataag aaaataagta aacatacatg ttataaaata
     2581 ttggaataat atacaattat aaatttgtta acactaatat ctatatgtta aaatatagta
     2641 gaagatgtta gtaaataata ggatgagttc tattttaata caattaaatt aagcttagtt
     2701 tgaaatttgt atctaaaaag taaagtaatc tagaattaag aaaatggaga tagaattata
     2761 atggaaaagt tatattatac aaatcagtat ataagagatt ttacagcaga aataattgaa
     2821 ataaaagaag tagaaaataa gtatcatgtt ttattagata agacagcttt ttttcctggt
     2881 ggaggaggtc agtttggaga cctgggaaaa atagagagtg atgatgtaat aaatgtgtat
     2941 gaagatggaa aaaaaatata ccatgtatta gataaaaaac ctataaagat acataaggta
     3001 aagtgtagta ttgattggga tagaagagaa gatggaatgc atcaacattt tggacaacat
     3061 gtattgtctg gatgtttttt taaaactttt aatgcaaata cgacaggttt tcatttggga
     3121 aatgagtata gtacagtaga tatagaaggt aatttagaag aggataaaat tagagagata
     3181 gagttgtttg ccaatgaaat tattcgtcaa aatatacaag tagagacatt acttccaacg
     3241 aaaaaagaac taaaaaagat ttggttaaga cgtgatttgc caaatactga tgaagagata
     3301 agagtaataa aaataggtga tttagatacg aatgcatgtt gtggagtgca tccaaaatca
     3361 actggtgaat tgagaatgat aaaaataaag aaatgggaaa aacataagtc aagtacaaga
     3421 atagagtttc tagcaggtaa aagggcagtg gatgaagtat tgaagaggga tatatatttg
     3481 actaaaatat gtagatattt aagctgtagt gaggaagatg ctataaatgg tattgtaaat
     3541 ctaaatagta aagtggaaga ggctttaatt aaaaaaagaa ggcttgaaga agtagtatct
     3601 acatatcagg tcaaagaaat gattgaaaaa gcaaataagg ttggcaatat ttcggtcatt
     3661 aaaaaaattt atgatgatga agatttgaaa tatgtaaata agatagcaaa taaaattgca
     3721 gaatatgaaa atagtattgc attattagct gttaaattta atgataaaat aaatttagtt
     3781 tttgcatgtt ctaaaaattt aaaagatatt aatatgggag ttttattaaa ggatgcaata
     3841 agtcttatag atggcaaggg tggtggaagt aaagtattag ctcaaggagg aggtaagaat
     3901 aatggaaatt tagaggctac acttgattat gcatttatga agatagaaaa aactctataa
     3961 atatattata taaaaaacct tagtagataa aatagatatg gaggaataag tatggagcaa
     4021 caaaaggact acatagagtt atatgaaaat gaagaactaa tagagataag agaagcacgt
     4081 atggatgatt tggatacaat agcaaaattt aattataatt tggctaaaga aactgaagga
     4141 aaagaacttg atatggatgt tttaactaaa ggtgtaaaag cattgttatt agatgagaga
     4201 aaaggaaaat atcatgtata tacagtattt gataaagttg ttgcacagat tatgtataca
     4261 tatgagtgga gtgattggag aaatggaaat ttcctttgga ttcagagtgt atatgtagat
     4321 aaggaatata gaagaaaagg tatctttaat tatttattta attatataaa aaatatatgt
     4381 gataaagatg aaaatatagt tggaatgaga ttatatgtag aaaaagaaaa cataaatgca
     4441 aaagcaacat atgagtcttt aaatatgtat gagtgtgatt ataatatgta tgaatacgaa
     4501 gtaatacatt cgtaatataa atttgtaata ctgttatact gatgttataa agtattgatt
     4561 atattgacga ttatatgaaa taaactggat attataatta gaatttttag ggggtataaa
     4621 aatgggcgtt ttaaaaggaa tgttttatgt
//
LOCUS       DAEPKC010000165         4622 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.168, whole genome shotgun sequence.
ACCESSION   DAEPKC010000165 DAEPKC010000000
VERSION     DAEPKC010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4622)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4622)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4622
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.168"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..465
                     /locus_tag="KR294_003593"
     CDS             <1..465
                     /locus_tag="KR294_003593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241636.1"
                     /translation="IKESSKNIYNATESQFKIRDYIKNINAGFALYERSAQDLLTKLM
                     THENKISQNQKILLDEKFTLDDSIKNLSSIIENFSNDLQVKLDMMFENSLDIQDKLDV
                     MFNNSFMNDEVPLDSEELFKDDVNNVFNPFSEEIYEIEDKEIKVIGEDELNE"
     gene            458..1090
                     /locus_tag="KR294_003594"
     CDS             458..1090
                     /locus_tag="KR294_003594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HBH0241637.1"
                     /translation="MNNKYRRTVNREFEKSSFWPTFTDLLSTVLMVVILILFSSESIS
                     GSVEQDLAKNVNASVEETFKKSGIPVKVDKSNGQVTFGEKTMFDVDSDVLKPEAKEML
                     KMFVPKYIETIYKDYGDYISKIVIEGHTDDVGSYIYNLDLSQRRAYSVAKFIVGDEIG
                     DYKYKDKVTKHIIAIGRSKAELIKNGDNSVNRDASRRVELKYEININQNK"
     gene            1419..2576
                     /locus_tag="KR294_003595"
     CDS             1419..2576
                     /locus_tag="KR294_003595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBH0241638.1"
                     /translation="MIEISIKNKKNSKIKTLILLLIVSISIYLTGCTTLDNGNNQSNN
                     NDSLSSSISSDKNVKIHFIDTGNSDAILIQDGKTFILIDGGDNDDEGLMVDYLNNQGV
                     KDIKYLIATHSHADHLGGLDSVVKNFNIENVFVSNGSAETKSYRDFINALANKGLSPS
                     VPLENNKFYLEDSYFEVLNTNGGDTTNEQSLVLVYTNGNDKVLFTGDAEEGTEKEILP
                     KLEKVDLLKVAHHGSRSSSSQEFLDKVNPEYAVLLVGKGNSYGHPHQETMNKLKKMGV
                     KVHRSDECSDIIFESTGDGVFTSCKDGSYNKGVREDGNSGKSNSNTSKNDSFKNKQNT
                     SNSEEIVYFTPKGKSYHSTKNCSGLSRSKKILSGTIAESKKNDPCDICYGK"
     gene            complement(2723..3358)
                     /gene="lexA"
                     /locus_tag="KR294_003596"
     CDS             complement(2723..3358)
                     /gene="lexA"
                     /locus_tag="KR294_003596"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HBH0241639.1"
                     /translation="MYLDLTEKQVLILEFIKSQIILKGYPPAVREICTAVGLRSTSTV
                     HSHLNKLEKLGYIRKDPTKPRAIEVLERSKVNDVSGANQEIIELPLVGQITAGEPILA
                     QQNIEEYIPFPASLVKGSNNFVLRVKGESMINAGILDEDYVVVDKKNTALNSQIVVAL
                     INGESATVKRFFKEGNLIRLQPENDFMEPIMLNDSEVEIVGIVTGVFRVIK"
     gene            complement(3462..4589)
                     /locus_tag="KR294_003597"
     CDS             complement(3462..4589)
                     /locus_tag="KR294_003597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBH0241640.1"
                     /translation="MNNDKKIIKVHNKSDKPDNIVIKENELIEKCLLLENKLPVFMKD
                     YFIYLKGSVAVSTRLAYLEDINFFCSYLIETKELTNADCVKDITEDDFNTIKSRDINL
                     FLGDYCSRYYKNTEKNTLIFENNNRALARKKSSISTLFKFLYRNSQIDNNITDGFNPI
                     KLPKPQPDAIKRLEIDEVAKMLESVETGEGLTEKEKVYWRKTKLRDKAILALFVTYGL
                     RLNELRELNISSFNFSRGEFKIYRKRGKEVLMPINHTCEHVIKDYLQNERTRDELLND
                     EEKDALFLSLQNKRITAKAIRTLVKKYTSIPLDTTRDNGYSPHKLRATAATSLIQTGF
                     SIYDVQNLLDHDNVTTTQLYAAHKKNVKRDIVKNFEWIEDD"
BASE COUNT         1694 a          600 c          687 g         1641 t
ORIGIN      
        1 ataaaagaat cttcaaaaaa tatatacaat gccactgaaa gccaattcaa aattagagat
       61 tatataaaaa atataaatgc aggatttgct ctatatgaaa gaagtgctca agatttatta
      121 actaaattaa tgacccatga aaataaaatc tctcaaaatc aaaaaatcct tttagatgaa
      181 aagtttacct tagatgactc aataaaaaat ctctcaagta ttattgaaaa cttttctaat
      241 gacctacaag ttaaactgga tatgatgttt gaaaattctt tagatattca agataagtta
      301 gatgttatgt ttaataactc ttttatgaat gatgaagttc ctcttgatag tgaagaatta
      361 tttaaggatg atgttaataa tgtatttaat ccttttagtg aagaaattta tgagatagag
      421 gataaagaaa taaaggtcat aggtgaggat gagttaaatg aataataaat atagaagaac
      481 tgttaacaga gaatttgaaa agagtagctt ttggccaaca tttacagatt tattatctac
      541 tgtattgatg gttgtaattc ttatcttatt tagctcagaa agtatttcag gttctgttga
      601 acaagattta gctaagaatg tcaatgcttc tgttgaagaa acttttaaaa aaagtggaat
      661 acctgtgaag gtagataaat ctaatgggca agtaactttt ggtgaaaaaa ccatgtttga
      721 tgtagatagt gatgttttaa aaccagaggc taaagaaatg ctaaaaatgt ttgttccaaa
      781 gtacatagag actatttata aagattatgg tgactatata tccaaaatag ttatagaagg
      841 tcatacagat gatgtgggaa gttatatata caacttagat ttatcgcaaa gaagagcata
      901 tagcgttgct aaatttatag tgggagatga aataggtgac tataaataca aagataaagt
      961 gactaagcat attattgcaa taggaaggtc aaaagctgaa ctcatcaaaa atggtgacaa
     1021 tagcgtgaat agagatgcat ctagaagagt agaactaaaa tacgaaataa atattaatca
     1081 aaataaataa ttaaattttt ataaaaaaaa agaaggcagt tggtgtgagc tttaagcctt
     1141 ctttaaggaa aaagtttatt tatttttgtt gatacttaac atattatagt ttttagaagc
     1201 agtttgcaat atattaaacg taaatggtcg tttaaaatgc ataactggat actactgatg
     1261 taaaatattt cattttatat aatataaaaa ttatacagta tcaattttct atattattgt
     1321 actataatct attatttaaa atattatgta aaaaaatatc ataaaaacgc atatcatgtt
     1381 ataattacta gagtattatg aatatggagg cgtagtttgt gatagaaata agtataaaaa
     1441 ataaaaaaaa ttctaaaatt aaaactttga tacttttatt gatagtatct atatcaattt
     1501 atttaactgg ttgtactaca ttagataatg gaaataatca atcaaataat aatgattctt
     1561 tgtctagtag tatatcaagt gataagaatg taaaaattca ttttattgac actggaaata
     1621 gtgatgcaat attgattcaa gatggtaaaa cttttatatt gatagatggg ggagataatg
     1681 atgatgaggg attaatggta gattacctaa acaatcaagg tgtaaaagat attaaatatc
     1741 ttatagctac ccattctcat gcagaccatt taggtggact tgattctgtt gtcaaaaact
     1801 ttaatataga aaatgttttt gtatcgaatg gttcagcaga aacaaagagt tatagggact
     1861 ttataaatgc tttagcaaat aagggtttat ccccaagtgt accgcttgaa aataataagt
     1921 tctatttaga agattcttat tttgaagttc taaatacaaa tgggggagat actactaatg
     1981 aacaatctct agtccttgta tatactaatg ggaatgataa agttttattt acaggtgatg
     2041 ctgaagaagg taccgaaaaa gaaatactcc ctaagcttga gaaagtagac cttttaaaag
     2101 tagctcatca tggttctcgt agtagttcat ctcaagagtt tttagataaa gtaaatcctg
     2161 aatatgcggt tcttttagta ggcaagggta attcatatgg tcatccacat caggagacaa
     2221 tgaataaatt aaaaaaaatg ggagtaaaag tacatagaag tgatgagtgt tcagatataa
     2281 tatttgaatc aacaggtgat ggagtattta caagttgtaa agatggaagt tataataaag
     2341 gcgttagaga agatggaaac tctggaaaat caaacagtaa tacaagtaaa aatgattctt
     2401 ttaaaaataa acaaaataca tccaattcag aagaaatagt gtattttact ccaaaaggta
     2461 agagttatca ctctacaaaa aattgtagtg ggctttcaag aagtaaaaaa atattatcag
     2521 gcacaattgc agaaagtaag aaaaatgacc catgtgatat atgttatgga aaataacaaa
     2581 aaaacaacca atttatctat aaagcttctg aactttaaat catttaaaaa ataaaataaa
     2641 tgcataaaaa aataagctat aatcaataga taacacattt tatctatacg aatagcttat
     2701 ttttttaagt attttttaat agctatttaa taactctaaa tacaccagtt acaataccta
     2761 caatttcaac ttctgagtca ttgagcataa ttggttccat aaaatcattt tctggctgaa
     2821 gtcttattaa atttccttct ttaaaaaacc tcttaactgt agcagattca ccatttataa
     2881 gtgcaactac tatctgagaa tttaaggctg tatttttttt gtctactaca acgtaatctt
     2941 catctaaaat tcctgcatta atcatacttt cgccttttac tcttaataca aaattgttac
     3001 tgccctttac taaactggca gggaatggaa tgtattcctc tatgttttgt tgagctaaaa
     3061 tgggttctcc agctgttatt tgacctacta aaggaagctc tattatttct tgattagctc
     3121 cagaaacatc atttacttta ctacgttcta aaacttcaat agctcttggt ttagtagggt
     3181 cctttcttat gtatcccagt ttttcaagtt tatttagatg agagtgcaca gttgaagtag
     3241 atcttaaccc tacagcagta catatttctc ttacagcagg tggataacct tttaatatga
     3301 tttgagactt tataaattcc aatatcaaga cttgcttttc agttagatct aaatacataa
     3361 catcactcat ttccaaacat attttgtttt tatttccata cactttatat ttttaattat
     3421 aacataatcc atttatatct gcaaacattt gttcctgatt tttaatcgtc ctcaatccat
     3481 tcaaaattct tgactatatc acgttttaca tttttcttat gagctgcata aagctgagta
     3541 gttgtgacat tatcatggtc aagtaagttt tgaacatcat atatagaaaa tcctgtttgg
     3601 attagagaag ttgcagccgt tgctcttaat ttatggggac tatatccatt gtctctagta
     3661 gtatcaagtg gaatagatgt atattttttt accagtgttc ttatagcctt tgctgtaatt
     3721 ctcttatttt gaagagacaa aaataaagca tctttttctt catcatttaa tagttcatct
     3781 cttgttcttt cgttttgcaa ataatctttt attacatgtt cacaagtatg atttataggc
     3841 attaaaactt ctttcccacg ttttctatat attttaaatt cacctcttga aaaattaaaa
     3901 gaggagatat tgagttctct aagctcattt aatctaagcc cgtatgtaac aaataatgct
     3961 agtatagctt tgtcacgtaa tttagttttt ctccaatata ccttttcttt ctctgtaagc
     4021 ccttcacctg tttctactga ttcaagcatc ttagcaactt catctatctc aaggcgctta
     4081 atagcatctg gctgaggttt aggaagtttt attggattga atccatcagt tatattatta
     4141 tctatctgag agtttctgta taagaattta aatagagtag agatggatga tttttttctt
     4201 gctaaagctc tattgttatt ttcaaaaatc aatgtgtttt tttctgtatt tttgtaatat
     4261 ctactgcaat aatcacctaa gaataaattt atatctcttg attttattgt attaaaatca
     4321 tcttctgtaa tatcttttac acaatctgca tttgttaatt ctttggtttc aatcaaatat
     4381 gaacaaaaaa aattaatatc ttctaaataa gcaagtcgtg tagaaactgc aacagaacct
     4441 tttaaatata taaaataatc cttcataaat acaggaagtt tattttccaa aagtagacat
     4501 ttttctatga gttcattttc tttgataaca atattatcag gtttatctga tttattatgt
     4561 acttttataa ttttcttatc attattcaaa attaaacctc ctaaaactaa aatataaatc
     4621 tt
//
LOCUS       DAEPKC010000166         4312 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.169, whole genome shotgun sequence.
ACCESSION   DAEPKC010000166 DAEPKC010000000
VERSION     DAEPKC010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4312)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4312)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4312
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.169"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(<1..436)
                     /locus_tag="KR294_003598"
     CDS             complement(<1..436)
                     /locus_tag="KR294_003598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HBH0241641.1"
                     /translation="MISELMLKNFRKSSINFKTKIKLNLREKPDINSLKLKSIPEGKI
                     VKLKCVDGIWAEVESNYDKGWLLYKYLERLSNAKNNSNDTIKNRKKNYIGNIRTNGLS
                     LELRNDRTLESKVITTIPDGFKVEVCYSVGKWARVNINKNEKR"
     regulatory      complement(519..612)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            complement(966..1349)
                     /locus_tag="KR294_003599"
                     /pseudo
     CDS             complement(966..1349)
                     /locus_tag="KR294_003599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431032.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
     regulatory      1575..1672
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            1727..1903
                     /locus_tag="KR294_003600"
     CDS             1727..1903
                     /locus_tag="KR294_003600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241642.1"
                     /translation="MFGNKMDKCTHVLTAYISSSYDYCNFLDTQLDDFILEYGENVVE
                     SCLHQVMVLVSKYN"
     gene            2129..2329
                     /locus_tag="KR294_003601"
     CDS             2129..2329
                     /locus_tag="KR294_003601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003723180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBH0241643.1"
                     /translation="MNNGIVKWFNNEKGFGFISMEGRDDVFAHFSAIQTSGFKSLEEG
                     QQVSFDIVKGARGPQAENITIL"
     gene            complement(2493..2705)
                     /locus_tag="KR294_003602"
     CDS             complement(2493..2705)
                     /locus_tag="KR294_003602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241644.1"
                     /translation="MVCKIFITLKTILPKTQIIVTTHSPHILQIDSKEEMIVLDMAES
                     DNVYKKELKLGEYGVLGWTNEGLYLH"
     gene            3080..3262
                     /locus_tag="KR294_003603"
     CDS             3080..3262
                     /locus_tag="KR294_003603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HBH0241645.1"
                     /translation="MFKFYNNATLMFLPGTNIKTISERLGHADIKITMNSYSQFLEEM
                     DREAFENLSKILFIVF"
     gene            3333..4178
                     /locus_tag="KR294_003604"
     CDS             3333..4178
                     /locus_tag="KR294_003604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241646.1"
                     /translation="MNIIKSITLLLTLLIVILMTGCSPRESASEVAKKYIDKMNSGDY
                     ETAYSLLSKDSKKKISIENLEEFQNILVSTKRIISYKIGKEKIIKKYKHDGKEYKNVV
                     KLEETFNIKNLLYKKDDSLKVNRYFVVENNKYKLLLYESFKKEFGINSMDLAQLKLND
                     FGLKYFKEVDLILKKAIAINPTDSKLYYAQACNYMNFDGFPGYSDTTYNALDSINKSL
                     KYLDKNDSDYKKNASNIYNLKGVILMFHKRFDEAQQYLNKALYFNKDNKDPKYNLNTI
                     KKHLN"
BASE COUNT         1597 a          546 c          490 g         1679 t
ORIGIN      
        1 atcgtttttc atttttattg atattaactc ttgcccattt tccaacgcta taacatactt
       61 caactttaaa accatcaggg attgtagtta taactttaga ttctaatgtt ctatcatttc
      121 taagttctaa acttaatcca tttgttctta tatttcctat gtaattcttt tttctatttt
      181 ttattgtatc attactattg tttttagcat tacttaatct ttctaaatat ttataaagta
      241 accaaccttt gtcataatta ctctcaactt ctgcccatat tccatctaca cactttaact
      301 taacaatttt accttctggt atacttttta atttcaaact atttatgtct ggtttttctc
      361 ttaaattcaa tttaatttta gtcttaaaat tgatgctaga tttgcgaaaa ttttttaaca
      421 ttaattcaga tatcatctta agccctcctc ttgccaaata ttaagttatt aaaatatata
      481 actctaaaaa tacttttaac aaaaagaatt attatctttt tggcaactgg ctgacatgac
      541 ctttattaca taaagatttt agtccctata gttttgcgtc attagattta tctaatattg
      601 cctatatctg aataataaca taatttgaac aattaaaaaa taatattacc tcaaatttta
      661 tattatttaa atataaatta aatttttaat taataataat caaaaaatat ctttatattt
      721 attcaattac tgttctttat agtcaatata aaagacagta atttatctat agtgttactt
      781 atattttata tatatggcta tttttcaaca ttttacaata tataacattt atttttttaa
      841 cttttgtcag taaaatgtca gcaaaacact ttatccacaa tttttatata agttttccac
      901 aacttatcac caatattatc cacataaaaa aggtagcact tatattatta gctacctttt
      961 atttattaat ctttatattt ccagcttttt atccaacttc ctatttctat tattttttct
     1021 tcagttattt cttctccatc atgtaatttt gaaattaatt ctgataaagg attgttatgt
     1081 aaacctctaa aaactctttt tccctctatt ttgagatatt ctctctcttt tattaatact
     1141 gtatagtgta catgcctccc aattctctat gatattaaaa aacctttttt ggttaatcta
     1201 gctaaaagta taattgtagt tgtatgcttc caaccatatg ttttttctat ttcatctgca
     1261 acatcttttg atattacagt tttataacca gtatgccata tgcatttcat aatttttaat
     1321 tctgtatctg gtaatttttt atttagcata atatattcct tctttcaatt tatgtcactt
     1381 cttcaaattt atctagctta aattataata ggagcttttt agaacaaaaa ctatatttaa
     1441 tttttaccag gtactctacg tgtttagtct gtttttaagt gtaaaataat gttcatatct
     1501 ataaatttat ttaactttca aacaatcctg ttgaataata actaattcta ttgtattatt
     1561 ttagttgtag aataaaacta aatcggcaaa actagagaaa tttagtgacg caaagctata
     1621 gggactaaga cttatataaa tatcttatga gttatgtcag ccagttgcca aagagatagt
     1681 gttctttttg tttttatgaa agttttttag ggggataata atttatatgt ttggaaataa
     1741 aatggataaa tgtacacatg tattgactgc ttatattagc agttcgtatg attattgtaa
     1801 ttttttagat acacagttag atgattttat attagagtac ggagaaaatg tagtagagtc
     1861 ttgtttacac caagtaatgg tattggtaag taagtataat tagatagaca ttgatttcta
     1921 gaaaaccctt tttagtttta tctacattta tattaatata tagcaatgta aaacgtttaa
     1981 atatattttt aatattaaga ataattaaaa tgttaactaa aaaatataat taagtagaca
     2041 tttctattaa tctatgatac aatagtattt gtggtaatac acaattaaat caagtatatc
     2101 ttgatatagg ttaataggag tatttttaat gaataatgga atagtgaaat ggtttaataa
     2161 tgaaaaagga ttcggtttta tatcaatgga aggtagagat gatgtgtttg ctcatttctc
     2221 agctatacaa acttcaggat ttaaatcatt agaagaaggt caacaagtaa gctttgatat
     2281 agttaaaggt gctagaggtc ctcaagcaga aaatataact atattataat atatagattt
     2341 ttcgggaaag actcttttta gagtcttttt ttattgttaa tatatgtaag ataatcattg
     2401 gtgaagtaaa taaggtatat tgagtaatgt tcttgatagt ttatatgcta atgaatttca
     2461 aaaaaataag cactcctata aaaagagtgc tcttaatgta aatataaacc ttcattggtc
     2521 cagcctaata ccccgtattc tccaagtttt aactcttttt tatatacatt atcactttca
     2581 gccatatcta acacaatcat ttcttcttta gaatcaattt gtaaaatatg aggactgtgt
     2641 gttgtgacaa ttatttgtgt ttttgggaga attgttttta atgtaataaa aattttacat
     2701 accacatagt tgatataaaa cttaagacta gcagactcat aagcaattag ttgcctctct
     2761 ttacatacca catagttgat ataaaaccta gaggctctca gagaagttat aagatgttta
     2821 gtaactttac ataccacata gttgatataa aactccaaaa taaacttagc atctccaatg
     2881 tttacacata tacaatgctc ttaaaattgc agtgaacgcg caatattgca attgataata
     2941 cttatcatat attctcaata ccttatattt caactgctaa acctcaattt atcacaaata
     3001 tcgctcactg caaaatttct atatttttat tatatcatag catataatta atattttcaa
     3061 ttaattttta catttaatta tgtttaaatt ctataataat gcaactttaa tgtttcttcc
     3121 tggaactaat ataaaaacta tttcagaaag attaggtcat gcagatataa aaataactat
     3181 gaatagctac tctcagtttt tagaagagat ggacagagaa gcatttgaaa atttgagcaa
     3241 aatactattt attgtatttt aaagaagatg acttattcaa tatttgatgc tagaatataa
     3301 ttaataaaaa tttaattata ggtgattgta ttatgaatat tattaaaagc ataactttac
     3361 tcttaacatt attaattgtg atattaatga caggctgttc cccaagagaa agtgctagtg
     3421 aagttgcaaa aaaatatatt gataagatga actctggtga ctatgaaaca gcatatagtt
     3481 tattaagtaa agatagtaaa aaaaaaatta gtatagaaaa tcttgaagaa tttcaaaata
     3541 ttttagttag tacaaaaaga ataattagtt ataaaatagg taaagaaaaa atcataaaaa
     3601 aatataaaca tgatggaaaa gaatataaaa atgttgttaa attagaagaa acttttaata
     3661 taaaaaacct tctttataaa aaagatgatt ctctaaaagt aaatagatat tttgtagttg
     3721 aaaataacaa atacaagcta ttattgtatg aaagtttcaa aaaagaattt ggtattaata
     3781 gtatggacct tgctcaactt aagcttaatg attttggact aaaatacttt aaagaagttg
     3841 accttatact aaaaaaagct attgctatta atcctactga ttcaaagctt tattatgccc
     3901 aagcatgtaa ttatatgaat tttgatggat ttcctggtta ttcagataca acatataatg
     3961 ctttagattc aattaataaa tctttaaagt atttagataa aaatgattct gactacaaaa
     4021 aaaatgcaag taatatatat aacttaaaag gagttattct tatgtttcac aaaagatttg
     4081 atgaagcaca acaatattta aataaagcct tatactttaa caaagataat aaagacccaa
     4141 aatataatct aaatacaata aaaaaacatc taaactagat atttaatttt tgaatttata
     4201 aaatattttt ttatgtataa ttcagcactg aatcataatc tctactaaac taattacaag
     4261 tttaaattat aaagacttat ttctatataa atattactct ataacaataa gt
//
LOCUS       DAEPKC010000167         4271 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.170, whole genome shotgun sequence.
ACCESSION   DAEPKC010000167 DAEPKC010000000
VERSION     DAEPKC010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4271)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4271)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4271
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.170"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..628
                     /locus_tag="KR294_003605"
     CDS             <1..628
                     /locus_tag="KR294_003605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008819588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="spore surface glycoprotein BclB"
                     /protein_id="HBH0241647.1"
                     /translation="ADGATGPTGATGATGVTGATGPTGPTGATGATGATGASAIIPFA
                     SGIPLSLTTIAGGLVGTPGFVGFGSSAPGLSIVGGVIDLTNAAGTLTNFAFSMPRDGT
                     ITSISAYFSTTAALSLVGSTITITATLYQSTAPNNSFTAVPGATVTLAPPLTGILSVG
                     SISSGIVTGLNIAATAQTRFLLVFTATASGLSLVNTVAGYASAGIAIN"
     gene            797..1558
                     /locus_tag="KR294_003606"
     CDS             797..1558
                     /locus_tag="KR294_003606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase"
                     /protein_id="HBH0241648.1"
                     /translation="MKNKIEISMNNFVKNYHKSNNITTKWQELLFAYASAEDDMFQKL
                     KSVVGTSHAMPKDFLENGKTIITYFIPFDESVNNSNIGGFECSEIWARAYIETNMLIS
                     NLNDFLCEELEKIGANSYAIPGSYNFDSEKLVSDWSQRHVAFIAGLGTFGLNNMLITE
                     KGCCGRIGSIITSLELEPTKRPENEYCLYKHNNSCKKCVNKCVKEALKEDGFNRNKCY
                     EMCMINEKKYTYIGGCDICGKCIVGVPCSVINPSR"
     gene            1867..2145
                     /locus_tag="KR294_003607"
     CDS             1867..2145
                     /locus_tag="KR294_003607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241649.1"
                     /translation="MSYKKAIHILPEELLELIQEYVDGECIYIPRKSNNKKEWGSNTP
                     TREELSIRNMQIYEDYQVGYDLQYLSEKYYLSLKSIQRIVLQEKRKDI"
     gene            2438..3013
                     /locus_tag="KR294_003608"
     CDS             2438..3013
                     /locus_tag="KR294_003608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1062 domain-containing protein"
                     /protein_id="HBH0241650.1"
                     /translation="MKKITWEVEYISQLPVIRYCKKCGKKTEYICSGLFRVNAQHKYL
                     DIWLIYKCSNCDSTWNSTIYSRVNPKSLNPEILEQFHTNDYNLVKQYAMNMELLHRNG
                     AEVGIPEYKIVGQEININDLTQVHIISKYPCQLKVSTLLREKLGLSRKVFDEMLDCGI
                     IRSNSGVDLKKGKLNYEIMLDIGKEKQKSSN"
     gene            complement(3119..3952)
                     /locus_tag="KR294_003609"
     CDS             complement(3119..3952)
                     /locus_tag="KR294_003609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prenyltransferase"
                     /protein_id="HBH0241651.1"
                     /translation="MNVENQSLSDIEIILSHRYDNGADYWTTPDKRLIKGSPFSTLDS
                     VLYLLELGVNPDDTLLKECADLIFSTWREDGRFKLYPNGGIYPCHTANAANVLCHMGY
                     ASDIRMQKTFQHFLDTQYTDGGWRCNKFSFGRGPETEYSNPLPTLNILNAFRFSNYLN
                     KESKLDKAVDFLLDHWTIKKPIGPCHYGIGTLFMQVEYPFRNYNLFLYVYVLSFYNRA
                     KKDKRFLEALKILESKMIGNKIVVERVVPKLSKLSFCKKGESSEIATTHYYEILKNLE
                     K"
     gene            complement(4020..>4271)
                     /locus_tag="KR294_003610"
     CDS             complement(4020..>4271)
                     /locus_tag="KR294_003610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3786 domain-containing protein"
                     /protein_id="HBH0241652.1"
                     /translation="IDKYKLVMEKIGAEKVNMGDLAYRFTYMGNTSMVFILWFGDDEF
                     PPNSNILFDSNIVYYFNAEDLAVVPDTAINAILNKINQL"
BASE COUNT         1583 a          551 c          714 g         1423 t
ORIGIN      
        1 ggcagatgga gcaacaggtc caacaggagc aacaggggca acaggagtta caggagcaac
       61 aggcccaaca ggcccaacag gagcaacagg agcaacagga gcaacaggtg ctagtgcaat
      121 aatacctttt gcatcaggta taccactatc acttacaact atagctggag gattagtagg
      181 tacacctgga tttgttggat ttggtagttc ggctccagga ttaagtatag ttggtggagt
      241 aatagacctt acaaacgcag caggaacatt gactaacttt gcattttcaa tgccaagaga
      301 tggaacaata acatctattt cagcatactt cagtacaaca gcagcacttt cacttgttgg
      361 ttcaacaatt acaattacag caacacttta ccaatctact gcaccaaata actcatttac
      421 agctgtacca ggagcgacag ttacactagc tccaccactt acaggtatat tatcagttgg
      481 ttcaatttct agtggaattg taacaggatt aaatatagca gcaacagcac aaactcgatt
      541 cttactagta tttactgcaa cagcttcagg tctttcatta gttaatactg tagcaggata
      601 tgcaagtgca ggaattgcaa taaattagat tagataagaa aaggcttcta atatcgtatt
      661 gatattagga gcttttttaa gaatgattga tgaacatagt tttaatatta attagtgcgc
      721 atattataaa atactattat ataatataaa ataataacat taaattggaa atatagaatt
      781 atctaggggt gatactatga aaaataagat tgaaatatca atgaacaact ttgtaaaaaa
      841 ttatcataaa tcaaataata taactacaaa gtggcaagaa cttttgtttg cttatgcatc
      901 tgctgaagat gatatgtttc agaagctaaa aagtgttgta ggaacatctc atgctatgcc
      961 aaaagatttt ctggaaaatg gaaaaactat aattacatat tttatacctt ttgatgaaag
     1021 tgtaaataat agtaatattg gagggtttga atgttctgaa atatgggcaa gagcgtacat
     1081 agaaactaat atgttgattt caaatttaaa tgatttctta tgtgaagaac tagagaagat
     1141 aggggctaat tcatatgcta ttcctgggtc gtataatttt gacagtgaaa aattggtaag
     1201 tgactggtca caaagacatg tagcattcat agcaggtctt ggaacttttg gtttaaataa
     1261 tatgcttatt acagaaaaag ggtgttgtgg aagaatagga agcataatca caagtttaga
     1321 attagagcca actaaaagac cagaaaatga atactgcttg tataaacata ataatagttg
     1381 caaaaaatgt gtcaataaat gcgtgaaaga agctttaaaa gaagatggat ttaataggaa
     1441 taagtgttat gaaatgtgta tgataaatga aaaaaaatac acttatatag gtggatgtga
     1501 tatttgtgga aagtgtatag ttggagttcc ttgttcagta ataaacccat caagataatg
     1561 gatttaagtt gactaataat tttaaagata gtttataatg aaaaaatttt agttatcaaa
     1621 ataaatataa tataaaaact aaataaatgt gtttaaaaaa tggataaata atttgtgttg
     1681 attgacaacc agttatactg ttgatagact tatatgtatc gctgtgatat ataaggaggg
     1741 ttgagatttt atgtttgatt taatctttat ttttgcatag caagggctat tgcaactatg
     1801 aaatttaata tataaatagc cctttgctat tcctaatgaa aaattactat ttaataggag
     1861 agcaaaatga gctataaaaa agcaatacat atattaccag aagaattact tgaattaata
     1921 caggaatatg tagatggtga atgtatctat attcctagaa aatctaataa taaaaaagaa
     1981 tggggaagta atacacctac tcgtgaggag ttgtcaatta gaaatatgca gatttacgaa
     2041 gactatcaag ttggatatga tttgcaatat ttatcggaaa agtattattt atctttgaaa
     2101 agtatccaaa gaattgtatt acaagaaaaa agaaaagata tctaaggatg agccagtata
     2161 gttttataat tatactggct cattttcttt tgataaaagt gtttgaggta tagtttcttt
     2221 taagtggatg atataattta agtaatttca ataacttata cagtagctaa caaagctggt
     2281 tgtaaagtat ctaataagaa gtagtagctt tttatatgtt tgaaattaaa atttattaaa
     2341 attaggaggt cttgttttga aaaaaatact tgattatatt ccaccttttc ataactttct
     2401 attaatttag taatcttata gaaaggaaat tgcatttatg aaaaaaatta cttgggaggt
     2461 ggaatatatc tcccagttac ctgtaattag gtattgtaaa aaatgtggaa aaaagactga
     2521 atatatttgt tcaggtttat ttagggttaa tgctcaacat aaatatttgg atatatggtt
     2581 aatatacaag tgttcaaatt gtgattcaac atggaactca actatatatt ctcgtgttaa
     2641 tccaaaaagc ttaaatccag aaatactaga acaattccat acaaatgatt ataatcttgt
     2701 taagcaatat gctatgaata tggaactttt acatagaaat ggagcagaag ttggtattcc
     2761 agagtataaa atagtaggac aagaaattaa tattaatgac cttacacaag ttcatattat
     2821 tagtaaatat ccatgtcagt taaaggtatc aacattatta cgtgagaaac taggtttatc
     2881 taggaaggta tttgacgaaa tgttggattg tgggattatt agaagtaact caggagttga
     2941 tttaaagaaa ggtaaattaa attatgaaat tatgttagat ataggcaagg agaagcaaaa
     3001 gtcttcaaat tgattagaat aactaactta atatattttc aggaacatca tttaaaaaaa
     3061 tagtgacttt aaaaaattta aagccactat tttttaatat gttttatcta tataactatt
     3121 atttttctag gttttttaat atttcgtaat agtgtgttgt ggctatttca cttgactcgc
     3181 cttttttaca aaaagataat ttagatagtt ttggaactac acgttcaacg acaattttat
     3241 tacctatcat tttagattca agtatcttca atgcttctaa aaatctctta tccttttttg
     3301 cacgattata aaatgataaa acgtagacat aaaggaatag gttataatta cggaaaggat
     3361 attcaacttg cataaataat gtgccaattc catagtgaca agggccgatt ggttttttaa
     3421 tagtccaatg gtcaagtaga aaatctacag ctttgtcaag ttttgattct ttatttagat
     3481 aattactaaa acggaatgca tttaatatat taagagttgg tagtggattt gagtattcag
     3541 tttctggacc tcgaccaaaa ctaaatttat tgcaacgcca cccaccatca gtatactgtg
     3601 tatctaaaaa atgttgaaac gttttttgca ttctaatgtc agatgcatat cccatatgac
     3661 agagtacgtt agcagcattt gcagtatgac aagggtaaat acctccattt ggatatagtt
     3721 tgaaacgtcc atcttctcgc catgtgctaa atatcaggtc agcacattct ttaagtaaag
     3781 tatcatcagg gttcacacct aattctaata gataaagtac actatcaaga gtagagaaag
     3841 gagaaccttt tattaaacgc ttatcaggtg tagtccaata gtctgcacca ttatcatacc
     3901 tgtgtgataa tattatttca atatctgata aagattgatt ttctacattc attttttact
     3961 ccatttcata ttatattcta ttaaatctat caaaaacttt attataatat tatttatatt
     4021 tataattgat ttattttatt taaaattgca tttatagctg tatcaggaac aactgctaaa
     4081 tcttctgcat tgaagtaata aactatatta gaatcaaata atatatttga atttggagga
     4141 aattcatcat ctccaaacca aagtataaat accatagatg tattacccat atatgtaaac
     4201 ctataagcta aatctcccat gtttactttt tcagctccaa ttttctccat aactaactta
     4261 tatttgtcta t
//
LOCUS       DAEPKC010000168         4223 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.171, whole genome shotgun sequence.
ACCESSION   DAEPKC010000168 DAEPKC010000000
VERSION     DAEPKC010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4223)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4223)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4223
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.171"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            258..2357
                     /gene="nrdE"
                     /locus_tag="KR294_003611"
     CDS             258..2357
                     /gene="nrdE"
                     /locus_tag="KR294_003611"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HBH0241653.1"
                     /translation="MNWIELNNQVIIKNEQGKYQLEKDKEALSSYIEEFIQPKLRKFN
                     NLEERLKYLIDEGYYSKEVINQYSIDVIKNIYDMIDKHKFEFQSYMSANKFYQNYALK
                     SNDGKEILETYNDKVLIVALTLGNGDKDLALNLADKIVKQEFQPATPTFLNAGRKRAG
                     EMVSCFLLSVEDSTEGISYAISSSNHLSKIGGGVALNLSKLRASGESIKDIEGAAGGV
                     VGVAKMLEQSFSYFNQMGARQGSGAVYLTVFHPDFELLMDTKKINADEKIRLATLSLG
                     AIIPDKFMELAEKNEVAYAFYPHTVYKKYGVSLDEIEMDEWYDKLVNDSDIRKKEINP
                     RQMLTKIAQMQQESGYPYVVYIDTANREHTLKDVGIIKMSNLCCEIFQYQTPSEIEGY
                     GGKNEWGQDISCNLGSLNIANVMDNKTIESTVETAIRALSFVADSTDIKPVPTVSNSN
                     SKSHSIGLGAMNLHGYLVRENILYTSDDAIDFSNVFFAMVRYYSIKASMKIAIERNQT
                     FEGFDKSEYVKGRNSKVLSKYYEQSYLPKSEKVRALFEGIYIPTKEDWTKLLDEVKEK
                     GIYNAYLMAVAPTQSISYVQNATSSIMPITEPVEVRTYGDSTTIYPMPFLTNDNMLYY
                     QSAYRMDMRKVIDLVATVQNHVDQGISTTLFVTDEKTTRDIARHYIYAYKKGLKSLYY
                     TRTKMTRDTHECLVCSV"
     gene            2369..3340
                     /gene="nrdF"
                     /locus_tag="KR294_003612"
     CDS             2369..3340
                     /gene="nrdF"
                     /locus_tag="KR294_003612"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HBH0241654.1"
                     /translation="MTFNLHKIHNAVNWNREEDGFTQAFWEQNVKQFWLPEEISVSKD
                     IKVWNELSNKEKELYKKVLGGLTLLDTKQGNNGIPSMMSLTENLQRKAVLSFMGTMEE
                     IHAKSYSSIFMTLLSNLEIDELFEWIETEPTLQRKADLVLAQYENTTNQEGLYLSMVT
                     SVFLESFLFYSGFFYPLYLSGQGKMVASGEIISLILRDESLHGKYIGLLAQEIYDSFD
                     KMDKEMLEEKMYSILYSLMENEIEYTNVIYRESGLEKEVVNFLKYNANRALENLGFEK
                     LYTVDAINPIVLNGLSTETKTHDFFSTKGNGYQKGVYEELEDEDFII"
     gene            3416..4042
                     /locus_tag="KR294_003613"
     CDS             3416..4042
                     /locus_tag="KR294_003613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HBH0241655.1"
                     /translation="MKYEWRKRDKELYLPKKNPVIVEIPEQKFIMLKGSGDPNSKEFT
                     EAIGVLYSLAYAIKTMPKKGIVPEGYFDYTVFPLEGIWDKGEKSKGLDVLIKEDLIYT
                     IMIRQPDFVTQDLLDKATDIVKKKKPHNLLEKVRFGSINEGLCVQMLHIGSYDNEPES
                     FDIMNEFCKKNKLIRKSYTHREIYISDARKVSPESLKTVLRFEVEREV"
BASE COUNT         1696 a          451 c          777 g         1299 t
ORIGIN      
        1 aaaatttctt taaataaaaa taatgtcaat tataaagtaa taaaagttta gatataaaaa
       61 aatttgtgta tatactatat gtagtatata atagataaag cactgactat atgtagtgct
      121 tttgtttttg aaaaatactt attgcatttc tataattata gattaatttt gggatttcaa
      181 ctgataagta ccaaaagaaa taataagcaa attaagtgaa attatggcac aagattatgt
      241 taaaaggacg gtaaataatg aattggatag agcttaacaa tcaagtgata attaaaaatg
      301 aacaaggcaa gtaccaattg gaaaaggata aggaagcctt aagtagttac atagaagaat
      361 ttatacagcc aaagttgaga aaatttaata acctagaaga aagattgaag tatttaatag
      421 atgaaggtta ttattcaaaa gaagtaataa atcagtatag catagatgtt attaaaaata
      481 tatatgatat gattgataaa cataagtttg aatttcaatc atatatgagt gcaaataagt
      541 tttatcaaaa ttatgcatta aagagcaatg atggaaagga aatattagaa acatataatg
      601 ataaagtgtt aattgtagct ttgacactag gaaatggtga taaagattta gctttaaact
      661 tggcagataa aatagtaaaa caagaatttc aaccagctac acctactttt ttaaatgctg
      721 gaagaaaaag ggctggagaa atggtatcat gttttttact atctgtagaa gatagtacag
      781 aaggtatatc atatgctata tcttcatcaa atcacttatc aaagattggt ggaggagttg
      841 cactaaattt atctaaactt agagcatctg gcgaatctat caaagatata gaaggtgcag
      901 ctggaggtgt tgttggagta gctaaaatgt tagaacaatc atttagttac tttaatcaaa
      961 tgggagctag acaaggttct ggtgcggtgt accttactgt attccatcct gattttgaat
     1021 tgttgatgga tactaaaaag ataaatgcag atgaaaaaat aaggcttgct acattatcat
     1081 taggagctat aataccagat aaatttatgg agttggcaga aaaaaatgaa gtagcatatg
     1141 cattttatcc tcatactgtg tataagaaat atggagtttc tcttgatgag atagaaatgg
     1201 atgagtggta tgataaattg gttaatgata gtgatataag aaaaaaagaa ataaatccta
     1261 ggcagatgtt gacaaaaata gcacagatgc aacaagaaag tggatatcca tatgtagtgt
     1321 acatagatac agctaataga gaacatacat taaaagatgt tggaattatt aaaatgtcta
     1381 acttatgttg tgagatattt caatatcaaa caccttcaga aatagagggg tatggaggaa
     1441 aaaatgaatg gggacaagat ataagttgta acctaggttc tttaaacata gctaatgtaa
     1501 tggataataa aactatagaa agtacagttg aaacagcaat aagagcactg tcatttgtag
     1561 cagatagcac agatataaaa ccagtgccaa cggtaagcaa tagtaacagc aagtctcatt
     1621 ctataggatt aggagctatg aatttacatg gatacttagt aagagaaaat attttatata
     1681 cttcagatga tgctatagat ttttctaatg tattttttgc aatggttaga tactattcaa
     1741 ttaaagcttc tatgaaaata gctatagaaa gaaatcaaac ttttgaagga tttgataaat
     1801 cagaatatgt taagggaaga aatagcaagg ttttatcaaa atactatgaa caatcttatc
     1861 tacctaagtc agaaaaggta agagcattat ttgaagggat ttatatacca acaaaagaag
     1921 actggacaaa attattggat gaggtaaaag aaaaagggat atataatgca tatttaatgg
     1981 cagtagcacc aactcaaagc attagttatg ttcaaaatgc tacatcaagt ataatgccaa
     2041 ttactgagcc agtagaagta agaacatatg gagactctac tacaatatat ccaatgccat
     2101 ttttaacaaa tgataatatg ttgtattatc aatcagcata caggatggat atgagaaagg
     2161 tcatagattt agtggcaaca gttcaaaacc atgttgacca aggtatatca acaacactgt
     2221 ttgttacaga tgaaaagaca actagagata tagctagaca ttacatatat gcctataaaa
     2281 aaggtttgaa aagtttatat tacacaagaa caaagatgac aagagatact catgagtgtc
     2341 tagtgtgttc agtataggga gagaaattat gacatttaat ttacataaaa tacataatgc
     2401 agttaactgg aatagagaag aagatggatt tacacaagct ttttgggaac aaaatgtaaa
     2461 acaattttgg cttcctgaag aaatatctgt ttctaaagac ataaaggtat ggaatgaact
     2521 aagtaataaa gaaaaggaat tatataaaaa agtattgggt ggtttaacat tactggatac
     2581 aaaacagggg aataatggaa taccatctat gatgagttta acagaaaacc tacaaagaaa
     2641 agctgtcttg tcttttatgg ggactatgga agaaatacat gcaaaaagtt attcttctat
     2701 atttatgact ctactttcta atttagaaat agatgaatta tttgaatgga tagaaacaga
     2761 accaacatta caaagaaagg ctgatttagt tttagctcaa tacgaaaata ctacaaatca
     2821 agagggatta tacctatcaa tggttacaag tgtattttta gagagtttct tgttttattc
     2881 aggattcttt tatccattgt atctatctgg tcaaggaaag atggtagcta gtggagaaat
     2941 aatatcgctt attcttagag atgagtcttt acatggtaag tatataggat tgctagcaca
     3001 agaaatatac gattcatttg ataaaatgga taaggagatg ttagaagaga agatgtattc
     3061 tatactttat agccttatgg agaatgagat agagtataca aatgttatat acagagaaag
     3121 tgggcttgaa aaagaggttg tgaacttttt aaaatacaat gcaaatagag ctttagaaaa
     3181 tctagggttt gagaagctat atactgtaga tgctataaat ccaattgtat taaatggtct
     3241 tagcactgaa accaaaacac atgatttttt ttcaactaag ggtaatggat accaaaaagg
     3301 agtgtatgag gaattagagg atgaagattt tataatataa tttataatta tgacacactg
     3361 ttgtcacttt tagcgtgata atatcaatgt ataaaatata tatggaggta tttttatgaa
     3421 atatgaatgg agaaaaagag ataaagagtt atatttacct aaaaagaatc ctgtaatagt
     3481 tgaaatacca gaacagaaat ttatcatgtt aaaagggagt ggagacccaa attctaaaga
     3541 atttactgaa gcaataggag tactttattc tttggcatat gcaataaaaa ccatgcctaa
     3601 aaaaggaatt gtaccagaag ggtattttga ctatacggtt tttcctttag aaggtatatg
     3661 ggataaggga gaaaaaagta aaggcttaga tgtacttatt aaagaagatt taatttacac
     3721 tataatgata cgtcagccag attttgttac acaagacctg ttggataaag ctactgatat
     3781 agtaaagaag aaaaaacctc ataatcttct tgaaaaagtt agatttgggt ctattaatga
     3841 agggctatgt gttcaaatgc ttcatatagg ttcatatgat aatgaaccag aaagctttga
     3901 cattatgaac gaattttgca aaaaaaataa acttataaga aaatcttaca cacatcgtga
     3961 aatttatata agtgatgcta gaaaagtatc gcctgaatca ttgaagacgg ttttacgttt
     4021 tgaagtagaa agggaagtat aaatattttg aataatttat aagagttata aaaagtgaag
     4081 tctgttgaga cttcattttt tgatgcaatt ttaaaattaa atttgatgtt tcataatatt
     4141 ttaaaaactt tctactttta ttagtgtgaa taactgttgc tattaaataa taatactaat
     4201 tatataagta ttattatata ata
//
LOCUS       DAEPKC010000169         4195 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.172, whole genome shotgun sequence.
ACCESSION   DAEPKC010000169 DAEPKC010000000
VERSION     DAEPKC010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4195)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4195)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4195
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.172"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(<1..308)
                     /locus_tag="KR294_003614"
     CDS             complement(<1..308)
                     /locus_tag="KR294_003614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1461 domain-containing protein"
                     /protein_id="HBH0241656.1"
                     /translation="MKKFLNVLFSICISIVIIVGVINFTVGFKQLYYFDIDYLNISEL
                     SGLSKDDIKLNYDYLIDYNLNKNVSEFKLPTLKSSPQGKIHFEEVRNIFQNINKLAKL
                     "
     gene            complement(337..1887)
                     /locus_tag="KR294_003615"
     CDS             complement(337..1887)
                     /locus_tag="KR294_003615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018592108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBH0241657.1"
                     /translation="MLVVENVSHGFGARTILENVSFRLRKGEHIALVGANGEGKSSFL
                     NIITKKLMPDAGNIKWSSRATVGYLDQHTVLSKGKTIREVLREAFKHMFDLEQEMIAM
                     YDKMGEASDDEMSKLLEETAEIQTILENSGFYMIDAKIQEVANGLGLGEIGLDKDVTD
                     LSGGQRTKVLLTKLLLENPTILILDEPTNYLDEEHITWLTKYLQEYENSFVLVSHDIE
                     FINNTCNVIYHMENGELNRYKGNYDEFVRLNDIKKRQEEQAYDKQVEERKRLEDFVAR
                     NKARVATRGMANSRQKQLDKMEILERPKEKIKPTFAFKDARAASKIIFETENLVLGYD
                     EALTKPLNFHLERGKKIALKGMNGIGKSTLLKTLLGIIKPFEGNVKLGDYLEVGYFEQ
                     ESSRENSNTPMDEVWSEFPGLTNFEVRQALAKCGLTNEHITSQMRVLSGGEAAKVRLC
                     KVMLKNINFLVLDEPTNHLDVEAKDELKKAIKEFKGTVLLVCHEPEFYSEIVDDVWNI
                     EDFTTKIV"
     gene            complement(2089..2973)
                     /locus_tag="KR294_003616"
     CDS             complement(2089..2973)
                     /locus_tag="KR294_003616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBH0241658.1"
                     /translation="MKKYRLLVTCIIAMGIIIIGTSNPVSNFYKTTNLISSGNITNEK
                     ANKDENSNKNNKDKNEDKSNSKSNKDKSSEDKSSDNKNEIQKNKKLLICIDPGHQGKG
                     DSNLEPVAPGSSSKKARVSSGTEGIATKKPEYVLNLEASLVLKSILESKGYNVIMTRE
                     THDVNISNSERAILANDKKADMVVRIHADSLNNSSKTGASILIPEKDGKYTAPIYEES
                     NKCAEFIKQNMEQSGIQINGIVQRGDLTGFNWSKVPAVLVEMGFMSNYNEDQMMSNPD
                     YQRKMMQCIADGLDAYFK"
     gene            3201..>4195
                     /locus_tag="KR294_003617"
     CDS             3201..>4195
                     /locus_tag="KR294_003617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S55"
                     /protein_id="HBH0241659.1"
                     /translation="MQLKNFHFKNNTLSKKTNLAKSKFTIVLTFLFLFLLYFFSNNLI
                     YAQNLQKNEPEYLIPIGNVLQIDAELKNIIVRNPGEASPFRLGDAIVKVNNAEVDGYS
                     DFANTLNALPEEKQVSILLNRGGQLITMKTTKHILEKISFNNLLSGFATLTYINPDTS
                     EFGAVGHPISVGNARKIPIKTGSISTTKHLNIEKSYKGSVGCINAKRENIIGSFTENT
                     DFGIRGQINNFDISKLKKYKVASLDEVKLGKAQIILQDNFNKCKKYNIEIIDIENQKH
                     PESKSFKIKITDKKLLAQTGGIVQGMSGTPIVQDNKIIGAVSHAIENDPAVGYGV"
BASE COUNT         1389 a          700 c          480 g         1626 t
ORIGIN      
        1 aataatttag ctaatttatt tatattttga aatatattcc tgacttcttc aaaatgtatc
       61 ttcccttgtg gagaagattt taatgttggt aatttgaact cagacacatt cttatttaag
      121 ttataatcaa ttagataatc gtagttcaat tttatatcat ctttagataa accagataac
      181 tctgatatat ttaagtaatc aatgtcaaaa taataaagtt gtttaaatcc aacagtaaaa
      241 ttaataacac ctactattat aacaatacta atacaaattg aaaaaagtac atttagaaac
      301 tttttcatga aatcccccca gcaataagtt aaatcactac acgattttag ttgtaaaatc
      361 ttctatattc catacatcat caacaatttc tgaataaaat tctggctcat gacatactaa
      421 aagaactgtt cccttaaact ctttgatagc cttcttcaat tcatcttttg cctcaacatc
      481 taaatgattt gtaggctcat ctaatactaa gaaatttata ttttttaaca ttactttgca
      541 aagtctaacc ttagcagctt ctccaccact taatactctc atttgactcg ttatatgttc
      601 atttgtaagt ccacattttg caagagcctg tctaacttca aagtttgtaa gccctggaaa
      661 ttcactccaa acttcatcca taggtgtatt actattttct cttgaactct cttgttcaaa
      721 atatccaact tccaaatagt cacctaattt aacatttcct tcaaatggtt ttattattcc
      781 aagtaaagtt tttaatagag tagattttcc aataccattc attcctttta aggcaatctt
      841 ttttcctctt tctaaatgga aattaagtgg ttttgtcaat gcttcatcat accctaaaac
      901 taaattttct gtttcaaaaa ttattttact agctgctcta gcatctttaa aagcaaaagt
      961 aggttttatt ttttcttttg gtctttctaa tatttccatc ttatcaagtt gcttttgtct
     1021 actgttagcc attcctctag ttgctactct agctttattt ctagctacaa aatcctctag
     1081 tctttttctt tcttcaactt gtttatcata agcttgttct tcttgacgtt tctttatatc
     1141 attaagtctt acaaattcat cataatttcc tttatatcta tttaactctc cattttccat
     1201 atgatatatt acattacatg tattatttat aaattcaata tcatgagaaa ctaagacaaa
     1261 actattctca tactcttgaa ggtacttagt aagccatgtt atatgctctt cgtctaaata
     1321 gtttgtaggc tcatccaata taagaatagt tggattttca agtagaagtt tagtaagaag
     1381 tacttttgtt ctttgccctc cacttaagtc agttacatct ttatcaagac caatttctcc
     1441 aagaccaaga ccatttgcaa cttcttgtat ctttgcatct atcatataaa aaccactatt
     1501 ttcaagtata gtttgtatct ctgctgtttc ttcaagaagc ttactcattt catcatcact
     1561 agcttctccc attttgtcat acatagcaat catttcttgc tctaagtcaa acatatgctt
     1621 aaaagcctct ctaagcactt ctcttatagt ttttcccttg cttaataccg tatgttggtc
     1681 taagtaacct actgtagctc ttgaagacca ttttatattt ccagcatctg gcataagctt
     1741 ctttgttatt atatttaaaa aactcgattt tccttctcca ttagcaccaa ctagtgcaat
     1801 atgttcacct tttctaagtc taaaggatac attttctaat attgttctcg caccaaatcc
     1861 atgactcaca ttttctacta ctagcatttc aacacctctc aaaaaaattt tacacattct
     1921 atactataat atattctttt taaacttaaa tcaagtattc ccaatatttt tagttatatt
     1981 tacgacaatt taacctaaaa taaacttctt ctttgtgtta tgtacaataa aaaatagaga
     2041 taaaaattag gaaaataata ccaacctaac tttttctcta ttcatatctt atttaaaata
     2101 cgcatccaat ccatcagcta tacactgcat catttttctt tggtagtctg gatttgacat
     2161 catttggtct tcattatagt tactcataaa tcccatttct actaatacag ctggtacttt
     2221 tgaccagttg aatccagtca aatcacctct ttgaacgatt ccattgattt gtatacctga
     2281 ttgttccata ttctgtttga taaattcagc acatttatta ctttcttcat atataggagc
     2341 tgtatatttt ccatcttttt caggaatcaa tatagatgct ccagtttttg aagaattatt
     2401 taaactatct gcatgtattc ttacaaccat atctgctttt ttgtcattag caagtattgc
     2461 tctttctgaa ttacttatat ttacatcatg tgtctctcta gtcattatta cattataacc
     2521 tttagattct aatatactct ttaaaacaag agatgcttct aagtttaaaa catattctgg
     2581 cttttttgta gcaataccct ctgttcctga agatactctt gcttttttag aggaagaacc
     2641 tggagctact ggttctaaat tgctatctcc ttttccttga tgccctgggt ctatacaaat
     2701 taaaagtttt ttattttttt gaatttcatt tttattatct gacgatttgt cctctgatga
     2761 cttatcttta ttacttttag aattagattt gtcttcattt ttatctttat tatttttgtt
     2821 tgaattttca tctttatttg ctttttcatt tgtgatattt cctgaactaa tcaaatttgt
     2881 agtcttgtaa aaattgctaa ctggatttga tgttcctata attatgattc ccatggcaat
     2941 tatacaagta actaacaatc tatatttttt cattttttgc tcctttctta tgctagacag
     3001 ttattgttta tttttattta tatgaatatg tatttatttt atcatataca ctatttattt
     3061 tatttatttt tatgaaaact aaggtgttat tgagctagtt ttccaagcat caaaacatga
     3121 ttcttgcaca acataatata gaagcagcaa gaaaacttca attctattat taaaataatt
     3181 taataagaaa gaggtgtttt atgcaactta aaaattttca ttttaaaaat aatactttaa
     3241 gtaaaaaaac caacttagct aagtcaaaat ttacaattgt tttaacattt ttatttttat
     3301 ttttattata ttttttctca aataatttaa tttatgcaca aaatttacaa aaaaatgaac
     3361 ctgaatattt aataccaatt ggaaacgtac ttcaaattga cgcagaatta aaaaatatca
     3421 tagttagaaa tcctggagaa gcatctccat ttagattggg tgatgctata gtaaaggtaa
     3481 ataatgctga agttgatgga tatagtgact ttgccaatac cttaaatgct ttaccagaag
     3541 aaaaacaagt atctatttta ttaaatagag gtggacaact tataacaatg aaaactacca
     3601 aacacatatt agaaaaaatt agttttaaca atttactttc tggatttgct actttaacgt
     3661 atatcaatcc agatacatca gagtttggag ctgtaggtca tccaataagt gttggtaatg
     3721 caagaaaaat acctattaaa acaggttcaa tttctacaac taagcacctt aatatagaaa
     3781 aatcttataa aggtagtgtt ggatgtataa atgcaaaacg agaaaatatt attggtagct
     3841 ttacagaaaa tactgatttt ggaataagag gtcaaattaa taactttgat atttccaagt
     3901 taaaaaaata taaagtagca tctttagatg aagttaaatt aggaaaagca caaataattt
     3961 tacaagataa ctttaataag tgtaaaaaat ataatattga aattatagat atagaaaacc
     4021 aaaaacatcc agaaagtaaa agttttaaaa ttaaaattac agataaaaag cttttagctc
     4081 aaactggtgg tattgtacaa ggtatgagtg gtactccaat agttcaagat aataaaataa
     4141 tcggagcagt gtcacatgca attgaaaacg acccagctgt aggttatggt gtatt
//
LOCUS       DAEPKC010000170         4180 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.173, whole genome shotgun sequence.
ACCESSION   DAEPKC010000170 DAEPKC010000000
VERSION     DAEPKC010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4180)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4180)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4180
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.173"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(173..460)
                     /locus_tag="KR294_003618"
     CDS             complement(173..460)
                     /locus_tag="KR294_003618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241660.1"
                     /translation="MRLNVTKQNTIEVENSRKEDVYFVIVDNVFFERQGDVFNSITNN
                     NLNNYDVKILPTDNVFLELKITSTKDLEPVFIVVEDRQYNHGSIMFKPVLV"
     gene            complement(480..755)
                     /locus_tag="KR294_003619"
     CDS             complement(480..755)
                     /locus_tag="KR294_003619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241661.1"
                     /translation="MSLFVGGWSKFRAVEEEDLKVFNEAVGMLEGVGYEPLIVSTQVV
                     AGTNFKFICNATSVTNPPQNYLAEIVVFKPLPCDEHNATITSINIIK"
     gene            complement(1392..1571)
                     /locus_tag="KR294_003620"
     CDS             complement(1392..1571)
                     /locus_tag="KR294_003620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241662.1"
                     /translation="MGKDRFEKVYSQGKINATEIWVDKETGVNYVFHYYGHAAGFTPL
                     LDREGKPVISPIVSK"
     gene            complement(1856..3331)
                     /locus_tag="KR294_003621"
     CDS             complement(1856..3331)
                     /locus_tag="KR294_003621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH0241663.1"
                     /translation="MKRKPQYLIIFEHIIQQIYTGKITIGDRLDSIKSMSEEYMVSKN
                     TIKTVIKMLSEKGFIETKAGSRPVLIQSTSKQSIESDLLYEKILQISEIYKIFSLIFP
                     SIAMYNIKRFTSKDFEELNEIIDCMEKNSSNYLVFKEQRLKYINKLISKTNNFLIHHF
                     CEIIQHDVIISQLAYNFDNLDNLDNCCIDFFRNKYIEQVRKTYLYGLDGNLIEFKKLL
                     TYMYKACRESILKMVENRAPQSIDTSSFNSVTLEKCYLYDLIVSDVICQIFEGNIKIG
                     DCLPSITSIINRYNVSLPTVRSAYNELNELGIAKTINGKGTYITLFSEYDDDYINTEE
                     GAKRLSLLLDAMEFVTITLEDVVLLLGNKMDLIAVDKIETHLRYLQNNCEECKVYPDF
                     VLLCKIVDYTQIYVLQETFLHLKQYMIFGIYLERFFHEEYNEILKTRFDVCFEILRYL
                     KKGDVERFAESFSNIFKESLQYLKKVISSLNVDMRVKLDIL"
BASE COUNT         1479 a          652 c          406 g         1643 t
ORIGIN      
        1 ctggtttaaa taggttatct ttatttgctt aaataagttc aactatactg gtttaaatag
       61 gttatcttta tttgcttaaa ttagttcaac tatactggtt taaatagttt tcctttagtt
      121 taaataattc acctatacct acttgaatag ttcactttta tttgcttaaa ttctatacca
      181 atactggctt aaacattata ctaccatgat tgtattgtct atcttcaact acaataaaaa
      241 caggttctaa atctttagta gatgttattt ttaattctaa aaaaacatta tcagttggta
      301 atatttttac atcataatta tttaaattat tattcgtgat actattaaat acatcacctt
      361 gacgttcaaa aaaaacatta tcaactatta caaaataaac atcttctttt ctactatttt
      421 caacctctat agtattttgt ttagttacat ttagtctcat cttccacctc ctattaatat
      481 tacttaatta tattaatact tgtaattgtt gcattatgtt catcacaagg aagaggttta
      541 aaaacaacta tctctgctaa ataattctgt ggaggatttg taactgaagt agcattacaa
      601 ataaatttaa aatttgttcc tgctacaact tgagtagaaa caataagtgg ttcataacca
      661 accccttcta acattcctac agcttcatta aatactttta aatcttcttc ttcgacagct
      721 ctgaattttg accatccacc aacaaaaaga ctcatataaa aacctccttt atatatatat
      781 ttatttatat atatagtagt accaattttc tcaatattca atattttctg tgtaactggt
      841 caatgaaaat gcataactgg ataaaaatac ttataaaata acttaacttt acatataaat
      901 agcttaattt acatgtaata agattattct acaatatgaa atacatctta ttttgaatat
      961 attctaaata caataatgga tattttcaat tattatactt agaaaatatc cattacttaa
     1021 tttgttttat ttaaaatcac atagagactt tattattttt tttattgcat gaatagctat
     1081 ttcaggtatc ataaggtgat ataccccctc cttgaaacca caaaaaacat aacaaacttt
     1141 acgaatcttg tcttaaaaga ccacaggtac attccttatt tgtggattgg agtagccata
     1201 acaagcaaat tttacaattt ttatgatgac aaaaatcaat aaaatcgctt agtatataac
     1261 acgaaatact acttgttgct attaagaata gttagatagg aagtatgcat tataccaata
     1321 aaggaatcaa taaagaaagt taaaacatcc ctacaaatta aaaatctgtt acatttttct
     1381 atatttaaac gttatttact tacaattgga gaaataacag gttttccttc tcggtcaagt
     1441 aaaggcgtaa atccggctgc atggccataa tagtggaata catagttcac acctgtttct
     1501 ttatccaccc aaatctccgt tgcatttatt tttccttgtg aatatacttt ttcaaatcta
     1561 tcttttccca ttttataatc ctccatattt ttgattggtc tatgccttct tcacttaagt
     1621 agaaaaaata cataacttat ttttttaatt ctaatatgag cacgtaaaaa tgtcaaacag
     1681 cttatttaat ttcataactt catgttactg ttcgtaacct tgtctgttta cttacactgc
     1741 attacagcac cattttatcc tttacattat tgtattgcac acagtaaaaa tgcttacttt
     1801 attggatttt tcaactaaaa aaaggatttt ttctccacag aacatttact attttttata
     1861 atatatctaa ttttactctc atatcaacat ttaatgaaga tataaccttt ttcaaatatt
     1921 gtaaagactc cttaaaaata ttagaaaaag attctgcaaa tctctcaaca tctccttttt
     1981 ttaaatacct aagtatctca aaacatacat caaaacgtgt tttcaaaatt tcattatatt
     2041 cttcatgaaa aaatctctct aaatagattc caaatatcat atattgtttt aaatgtaaaa
     2101 atgtttcctg taatacataa atttgtgtat aatctactat cttacaaagt aaaacaaaat
     2161 ctggataaac cttacactct tcacaattat tttgtaagta ccttaaatga gtttctattt
     2221 tatctacagc tatcaaatcc attttatttc ctagtaaaag tactacatcc tcaagagtaa
     2281 tcgtaacaaa ctccatagca tccaaaagca aactcaacct tttagctcct tcttctgtat
     2341 ttatataatc atcatcatat tcagaaaaaa gtgttatata tgttcccttg ccattaattg
     2401 ttttagcaat tcccaattca tttagctcat tataggcact tctaactgtt ggaagagata
     2461 cattatatct attaattatc gaagtaattg atggtagaca atctcctatt ttaatattgc
     2521 cttcaaaaat ttgacaaatt acatctgaaa caattaagtc atataaataa catttttcca
     2581 acgttacaga attaaaacta cttgtatcta tactttgtgg agcacgattt tctaccattt
     2641 taagtatgga ttctctacaa gctttataca tatatgttaa tagtttttta aattcaatta
     2701 gattcccgtc caatccatat aagtaagttt ttcttacctg ctctatgtat ttattacgaa
     2761 aaaagtctat acaacaatta tccaagttat ccaagttatc gaaattatag gccaattgtg
     2821 aaataatgac atcatgctga ataatctcac aaaaatggtg aatcaggaaa ttatttgttt
     2881 tacttattag tttatttata tattttagcc tttgttcttt aaagactaaa taattagaac
     2941 tatttttttc catacaatcg ataatctcgt ttaattcttc aaagtcttta gatgtaaatc
     3001 ttttaatatt gtacatagca atagaaggaa atattaaact aaaaatctta tatatttctg
     3061 atatttgtaa aatcttctca tataataagt cagattctat tgattgttta ctcgtactct
     3121 ggattaaaac tggtctagaa ccagcttttg tctctataaa gcccttttct gagagcattt
     3181 ttattacagt ttttatagta ttttttgata ccatatattc ttctgacatg ctttttatag
     3241 aatcaagcct atctccaata gtaattttac cagtataaat ttgttgaatt atatgctcaa
     3301 aaataattaa atattgtggt tttctcttca tatttttcct cttcgataaa ttagatttat
     3361 tgttttttgt aaggtatatt tacttttatt taatagggca aaatagttgc ttattttttc
     3421 ctcataatct ataattaata tagaccattt atatatatgg tctaagtttt ataatactgt
     3481 aatgcagtaa aatagcatat tgtagctata ctacagcaaa ttaacatacc attgtagtat
     3541 attaattgga ataattttaa gtacttcaaa attccagcaa aacatatatg tgtttttgat
     3601 attatgtata ttcgttaata gaatagctat acttgtttta cataataaat tatatgatac
     3661 ttgctatatg taattactat atttaataca cataactatt atacttacta tatgtaatta
     3721 ctatatttga tacacataat tattatactt actatatata attactatac ttggacacat
     3781 aactattata cttgctatat gtaattacta tactttatac acatagttat tatacatgct
     3841 atatataatt actacacttg gacacataac tactatattt actatatgta attatactat
     3901 acgtggacat atagttatca tacatactat atgtaattac tatacttgga cacataacta
     3961 ttatatttgc tatgtgtaat tatactatac ttggacatat agttatcata catactatat
     4021 aattactata cttggacaca ttatcataca tactatatgt aattactata cttatacaca
     4081 tagttatcat atatactata tataattact atacttggac acatagtcat catacatgct
     4141 atatgtaatt actatactta tacacataac tattatactt
//
LOCUS       DAEPKC010000171         4100 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.174, whole genome shotgun sequence.
ACCESSION   DAEPKC010000171 DAEPKC010000000
VERSION     DAEPKC010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4100)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4100)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4100
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.174"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            149..1747
                     /locus_tag="KR294_003622"
     CDS             149..1747
                     /locus_tag="KR294_003622"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative manganese-dependent inorganic
                     diphosphatase"
                     /protein_id="HBH0241664.1"
                     /translation="MSLLVFGHKNPDTDSICSAISLAHLKNKLGIKATAYALGDIRKE
                     AKYALDYFKVDAPEILDNVRIQVRDLNYDKVVPLTPTSSILEAYNLMDEKNVKTLPVT
                     YDDGTFAGIITMKEIAKNLLHQHFTTIHTSLSNICKNLNGTILVDCGEDIKGRVVTLS
                     FGMETLIETLKEGDIAIVGDRYDSIEYAIDTKVKLLILTNHTEISKDLLALAKINGVS
                     VVSVESDNYKTSNVINQCSFLDSIEATENLITFKEDDYMDEIKEIMLETNFRSYPILD
                     DDNKFLGLVSKGHLLNPSKKNVVLVDHNEYAQSADGIEQANIVEIIDHHKLGGISTDV
                     PMSFRVMPVGCNSTIIYQMYKENNVEIPYEIAGLLLSAILSDTLLFKSPTTTDMDKKA
                     CEELSKIAKVDMEKYAMDMFKCGTSLDEYTIEEIVNMDFKEFNMSGHRVGIGQVFTLD
                     IDSIFAKKDEFLSYINSTDYDKLILSVTDIIKEGSYLIYKAEDSLIANAFGVEGVQGT
                     FAPGVVSRKKQLVPNLTTAIKNFK"
     gene            complement(1982..4063)
                     /gene="bclA1"
                     /locus_tag="KR294_003623"
     CDS             complement(1982..4063)
                     /gene="bclA1"
                     /locus_tag="KR294_003623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like exosporium glycoprotein BclA1"
                     /protein_id="HBH0241665.1"
                     /translation="MRNIILYLNDDTFISKKYPDKNFSNLDYCLIGSKCSNSFVKEKL
                     ITFFKVRIPDILKDKSILKAELFIHIDSNKNHIFKEKVDIEIKRISEYYNLRTITWND
                     RVSMENIRGYLPIGISDTSNYICLNITGTIKAWAMNKYPNYGLALSLNYPYQILEFTS
                     SRGCNKPYILVTFEDRIIDNCYPKCECLPIRITGPMGPRGATGSTGPTGVTGPTGSTG
                     ATGSIGPTGPTGNTGATGSIGPTGVTGPTGSTGATGSIGPTGVTGPTGNTGVTGSIGP
                     TGATGPTGVTGEIGPTGVTGPTGVTGSIGPTGATGPTGATGVTGEIGPTGATGPTGNT
                     GVTGATGPTGNTGVTGVTGATGPTGATGVTGEIGPTGATGPTGEIGPTGATGPTGATG
                     VTGEIGPTGVTGPTGEIGPTGATGPTGVTGSIGPTGATGVTGEIGPTGPTGVTGSIGP
                     TGATGPTGNTGVTGVTGPTGATGPTGVTGEIGPTGATGPTGVTGEIGPTGATGPTGPT
                     GNTGATGSIGPTGVTGPTGATGATGVTGPTGPTGATGNSSQPVANFLVNAPSPQTLNN
                     GDAITGWQTIIGNSSSITVDANGTFTVQENGVYYISVSVALQPGSSSINQYSFAILFP
                     ILGGKDLAGLTTEPGGGGVLSGYFAGFLFGGTTFTINNFSSTTVGIRNGQSAGTAATL
                     TIFRIADTVMT"
BASE COUNT         1180 a          754 c          654 g         1512 t
ORIGIN      
        1 attaaatttg tagtatttat gtaagaaata aattttatat aatatttttt cactaaattt
       61 ttttcttttt acaacaaata ctcactacct tttgatataa tatttttatc aattattatt
      121 atattcaagt tttgaaagga gtattaaaat gagtttatta gttttcggac ataaaaatcc
      181 agatacagat tcaatatgtt ctgcaatttc attagcacat ttaaagaaca aactaggaat
      241 aaaagcaaca gcttatgctt taggagatat cagaaaagaa gctaaatatg ccttggatta
      301 ctttaaggta gatgcacctg aaattttaga taatgttaga atacaagtta gagatttaaa
      361 ttatgataaa gtagtacctt taacaccaac ttcatctata ttagaggctt ataaccttat
      421 ggatgaaaaa aatgttaaaa cactacctgt aacttatgat gatggaactt ttgctggtat
      481 cattactatg aaagaaatag ctaaaaatct acttcatcaa cactttacaa ctatacacac
      541 atcactatca aacatttgta aaaaccttaa tggtactatt cttgtggact gtggtgaaga
      601 tataaaaggt agagtagtca ctttatcatt tggaatggag actctaatag agactttaaa
      661 agaaggagac atagctattg ttggagatag atatgatagt attgaatatg ctattgatac
      721 aaaagttaaa cttttaatac ttactaatca tacagagatt tcaaaagatt tgctagctct
      781 tgctaagata aatggagtgt ctgttgtttc tgttgaaagt gacaattata aaacttctaa
      841 tgtaataaat caatgtagtt tcttagactc tatagaagct acagaaaatt taattacatt
      901 caaagaagat gattatatgg atgaaataaa agagattatg ctagaaacaa acttcagatc
      961 ttatccaata ttagatgatg ataataagtt tttaggttta gtttcaaaag gtcatctatt
     1021 aaacccatct aaaaagaatg ttgttttagt tgaccataac gaatatgctc aaagtgctga
     1081 tggaattgaa caagcaaaca tagttgaaat aattgaccat cataaacttg gcggtatttc
     1141 tactgatgtt cctatgtcat ttagagttat gcctgttgga tgcaatagta ctataattta
     1201 tcaaatgtac aaagaaaata atgttgagat accttatgaa atagctgggc ttcttttatc
     1261 tgctatatta tcagatacat tattatttaa gtctccaaca acaactgata tggataagaa
     1321 agcttgtgaa gaattaagta aaatagcaaa agtagacatg gaaaaatacg ctatggatat
     1381 gtttaaatgc ggtacttctt tagatgaata tactatagaa gaaatagtaa atatggactt
     1441 taaagaattt aatatgagtg gacatagagt tggtattgga caagtattta ccttagacat
     1501 agactctata tttgctaaaa aagatgagtt tttatcttat ataaattcga ctgattatga
     1561 taaattaatt ctttcagtta cagatataat caaagaaggt tcttatttaa tctataaagc
     1621 agaagatagc ttaattgcta acgcatttgg tgttgaaggt gttcaaggca catttgcacc
     1681 aggtgttgta tcaagaaaaa aacaattagt ccctaattta actactgcaa tcaaaaattt
     1741 taaataatat aaaattttta aataacgaaa actgtctcaa atctatattt gagacagttt
     1801 tttattatat atatattgat aataaagtta aataaaaatc cataaattta aaatttttat
     1861 gaatatattt tattattatt gttattttat tcattctaaa ataggtaaaa ctcaatatat
     1921 aaaaatactt ttgtcattta aataaaacct aaatagtttt taagattatt ttagacacgt
     1981 tttaagtcat aacagtatca gctattctaa atatcgtcaa agtagccgca gttcctgctg
     2041 attgcccatt tcgtatccct actgttgtag atgaaaagtt atttattgta aaagtagtcc
     2101 caccaaataa aaaaccagca aaatatccag aaagtactcc tccgcctcct ggctcagtag
     2161 taagccctgc caaatctttt cctcctaaaa ttgggaatag gatagcgaaa gaatattgat
     2221 ttatacttga tgaacctggt tgtaatgcta ctgaaactga tatataatac acaccatttt
     2281 cttgtactgt aaacgtacca tttgcatcta ctgttatact tgaactattt cctattattg
     2341 tttgccaacc tgttatagca tctccattat ttagtgtttg tggagatggt gcatttacga
     2401 ggaagttagc aactggctga gaggaattgc ctgttgctcc tgttggacct gttgggcctg
     2461 ttactcctgt cgctcctgtt gctcctgttg gacctgttac tcccgttggc cctatacttc
     2521 ctgtcgctcc tgtatttcct gttgggcctg ttggtcctgt tgctcccgtt ggtcctattt
     2581 ctcctgttac tcctgttggg cctgttgctc ccgttggtcc tatttctcct gtcactcctg
     2641 ttgggcctgt tgctcccgtt gggcctgtta ctcctgtcac tcctgtattt cctgtcggtc
     2701 ctgttgctcc cgttggtcct atacttcctg tcactcctgt tgggcctgtt ggtcctattt
     2761 ctcctgtcac tcctgtcgct cctgttggtc ctatacttcc tgtcactcct gttggtcctg
     2821 ttgctcctgt tggtcctatt tctcctgttg ggcctgttac tcctgttggc cctatttctc
     2881 ctgtcactcc tgtcgctcct gttgggcctg ttgctcccgt tggtcctatt tctcctgttg
     2941 ggcctgttgc tcctgttggc cctatttctc ctgtcactcc tgtcgctcct gttggacctg
     3001 ttgctcctgt tactcctgtt actcctgtat ttcctgttgg acctgttgct cctgttactc
     3061 ctgtatttcc tgttggacct gttgctcccg ttggtcctat ttctcctgtc actcctgtcg
     3121 ctcctgttgg acctgttgct cctgttggtc ctatacttcc tgtcactcct gttgggcctg
     3181 ttactcccgt tgggcctatt tctcctgtca ctcctgttgg gcctgttgct cccgttgggc
     3241 ctatacttcc tgtcactccc gtatttcctg tcggacctgt tactcctgtt ggtcctatac
     3301 ttcctgtcgc tcctgtactt ccggttgggc ctgttactcc cgttggccct atacttcctg
     3361 ttgctcctgt atttccggtt gggcctgttg gtcctatgct tcctgtcgct cctgtacttc
     3421 cggttgggcc tgttactcct gttgggcctg tacttcctgt cgctcctctt ggtcccattg
     3481 gacctgtaat tctaattgga agacactcac atttaggata acaattatct ataattctat
     3541 cttcaaatgt tacaagtata tacggtttgt tacaacctct actagatgta aattcaagaa
     3601 tctgataagg gtaatttaaa gataaagcta acccataatt aggatattta ttcattgccc
     3661 atgcttttat agttcccgta atatttaaac aaatatagtt ggatgtatca cttatcccaa
     3721 ttggtaaata tcccctgata ttttccatag acactctatc attccatgtt atagttcgta
     3781 aattataata ttcacttatt cttttaattt caatatctac tttttcttta aaaatatgat
     3841 tcttatttga atcaatatga ataaataact ctgcttttaa tatacttttg tcttttaata
     3901 tatctggtat tctcacttta aaaaaagtaa tcaacttttc ttttacaaaa ctatttgaac
     3961 atttacttcc tattaagcaa taatctaaat tactaaagtt tttatctgga tattttttag
     4021 atataaaagt atcatcattt aaataaagta taatatttct catttataat ccctccattt
     4081 tgggtctata tcatactatg
//
LOCUS       DAEPKC010000172         3993 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.175, whole genome shotgun sequence.
ACCESSION   DAEPKC010000172 DAEPKC010000000
VERSION     DAEPKC010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3993)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3993)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3993
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.175"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..698
                     /locus_tag="KR294_003624"
     CDS             <1..698
                     /locus_tag="KR294_003624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0241666.1"
                     /translation="AICDDESYMLNHLKENIELYMKQKNLLYNIELFNKVEDLLCNHE
                     KFNIVFLDIQMEEINGMQAARKLRSYGNECFIIFVTVLNEFVFDAFEVDAINYLIKPL
                     SNEKLYKTLDKIVTKLDDNESNYITIQKGYSYWKLKLADILYCEVIKRKIYVHLKKET
                     VDYYETIENLERSLPTNFFRCHRSYIINLQYVYGYENGNAVMESGDRIPVSRLRQQIF
                     SKVMLEFMKNRRI"
     gene            700..2058
                     /locus_tag="KR294_003625"
     CDS             700..2058
                     /locus_tag="KR294_003625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBH0241667.1"
                     /translation="MINLFSSDLFLKYSFLFSFIVYRILMVIVQYYFLISFTNVNSKF
                     WCFILYSIISIFLIIINTYFNLYNLFSSQILFFLMTFLFVKYIIKQSTVLSIVSTLLV
                     YLIEQLVYGFTAPLNYLIFTSDINTDIYKFDINMGLSSLITIIIAGFIYWYSSKKFNI
                     KVMNFDKYIAILMIPLLLIILFMQSFEYSSNINIDTSLGIVKLLLNTSITEEIQAFLF
                     SIIGTICVFFSLFTFKKLIQALEDDKERAIMNQQIHAQKNYIEEAKSRLSQTISFRHD
                     FNNHLAIVNGLLKKDQILKAQDYLNKLEKVTSDLSFSCNTQNIVIDALFNNKLSIAKQ
                     LGIEVDCEVIIPQSTNMNDFDLCIVFANAIDNAIKACRVVDKQNRYLKLSTKLEGGFF
                     MIEIKNSYNPINNYTSGSGIGLLNIKEIAKKYQGAISIDKTSDYFQINVLLVISLHCA
                     SI"
     gene            2097..2582
                     /locus_tag="KR294_003626"
     CDS             2097..2582
                     /locus_tag="KR294_003626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241668.1"
                     /translation="MYLNRESLIYRNEEVTKMKVGNINGQAPITNGLDSCQSEVQGLE
                     QKKKSLQDEIEKVRSDKSIDGETAKLKIEALKKEMEEIENKIQELKGNKAKKTNKEEN
                     NVSEVNNNLLERKKEPSNNENVKQLYDVFERSNVDEQWDNTYRVLQDDKNLKVKFNRP
                     I"
     gene            complement(2845..3081)
                     /locus_tag="KR294_003627"
     CDS             complement(2845..3081)
                     /locus_tag="KR294_003627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241669.1"
                     /translation="MLLTHIYFNGQFKQTIELYKQAFNATVKTLIEDSCYLLIVHNEI
                     VIHNKFLILNDFGNKNGVSISEGYQPTDKIQTAS"
     gene            complement(3236..3460)
                     /locus_tag="KR294_003628"
     CDS             complement(3236..3460)
                     /locus_tag="KR294_003628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HBH0241670.1"
                     /translation="MTVYNLKLGQKGIIDNIAGNEKLMKRLLALGLIDGTEVEVKKIA
                     PLNDPIVIRFRGFDLAIRKSDAKNINLKNN"
     gene            complement(3557..>3993)
                     /locus_tag="KR294_003629"
     CDS             complement(3557..>3993)
                     /locus_tag="KR294_003629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="sodium:glutamate symporter"
                     /protein_id="HBH0241671.1"
                     /translation="AVIFRNLNDKINILELNFKLIDFLKELSLGIFLTLSLMNIDLFE
                     LSTLLPPILLIVTFQVIFIILFSIFICFRVLGKDFDSAIIISGLIGHGIGATPNALAN
                     MSSLTQKYGDSPKAFLVVPLVSGFLLDAISIPCILFFINILT"
BASE COUNT         1567 a          445 c          543 g         1438 t
ORIGIN      
        1 ttgccatttg tgatgatgaa tcctatatgc taaatcattt aaaggaaaat atagaattat
       61 acatgaagca gaagaattta ttatataata tagagctttt taataaagta gaagatttac
      121 tatgcaatca tgaaaagttt aatattgtat ttttagatat acagatggaa gagattaacg
      181 gaatgcaggc agctagaaaa ttaaggtcat atggtaatga gtgctttata attttcgtta
      241 cagttttaaa tgaatttgta tttgatgctt ttgaagtaga tgctataaat tatctgataa
      301 aacctctatc taatgagaaa ctatataaaa ctttggataa aatagttaca aaacttgatg
      361 ataatgaaag taattatatc acaatacaaa aaggttattc atattggaaa ttaaaacttg
      421 ctgatatttt atattgtgaa gttataaaaa gaaagattta tgttcattta aagaaagaga
      481 ctgtagatta ttatgagact attgaaaatt tagagagaag tttaccaaca aattttttta
      541 ggtgtcatcg tagttatata atcaatttac aatatgtata tggatatgaa aatggtaatg
      601 cagttatgga aagtggagat agaatacctg tttctagact acgtcaacaa atattttcaa
      661 aagttatgct tgagttcatg aaaaatagga ggatataaga tgattaattt attttcttcc
      721 gatttatttt taaagtacag ttttttattt tcttttattg tatatagaat tttaatggta
      781 atagtgcaat actattttct aatcagtttt acaaatgtta attcaaaatt ttggtgtttt
      841 attttatatt cgataatttc aattttttta atcattataa atacatattt taatttatat
      901 aatttatttt cttcacagat tctatttttt cttatgactt ttttatttgt aaagtacata
      961 ataaaacaat ctactgtttt atctatagta tcaactttgt tagtatattt aattgaacaa
     1021 ttagtatatg gatttacagc tccattaaat tacttgatat ttactagtga tataaataca
     1081 gatatttata aatttgatat aaatatggga ctatcttctt taattactat tataatagct
     1141 ggatttatat attggtatag ttctaaaaag tttaatatta aggtcatgaa ctttgataaa
     1201 tatatagcaa ttttgatgat tccattgttg cttataatat tatttatgca atcatttgaa
     1261 tatagttcaa atataaatat agatacaagt cttgggattg taaagctgct attaaatact
     1321 tctataactg aagaaattca agcttttctt ttttctataa ttggaactat atgtgtattt
     1381 ttttctctat ttacctttaa gaaactaatt caagctctcg aagatgacaa ggagagggca
     1441 attatgaatc aacagattca tgctcaaaaa aactatattg aagaagcgaa atcacgatta
     1501 tcacaaacta tatcctttag acatgatttt aataatcatt tagctattgt caatggattg
     1561 ttgaaaaaag accaaatttt aaaagcacaa gattatttaa ataagcttga aaaagtaaca
     1621 agtgacctat cattttcttg taatacacag aatattgtta ttgatgctct tttcaacaat
     1681 aaattaagta tagcaaaaca attaggcata gaggtagatt gtgaagtaat tataccccaa
     1741 agcactaaca tgaacgattt tgacctatgt atagtgtttg ctaatgctat tgacaatgca
     1801 attaaagctt gtagagttgt agataaacaa aataggtatt taaagctttc cactaagtta
     1861 gagggtggat tttttatgat agaaataaaa aatagctata atccaataaa taattataca
     1921 agtggctcag gtataggtct tttaaatata aaagaaattg ctaaaaaata tcaaggggct
     1981 ataagtatag ataagacatc agattatttt caaataaatg tattgctggt tatttcatta
     2041 cattgcgcta gtatttgata acaatttcat tgaaaatagt atttgtaagc tatattatgt
     2101 acttgaatag agaaagtttg atatatagaa atgaggaggt tactaaaatg aaagttggaa
     2161 atataaatgg tcaagcacca attacaaatg gtttagatag ttgtcaaagt gaggtacaag
     2221 gcttagaaca aaagaaaaaa tcattacagg atgaaataga gaaagtaaga agtgataaaa
     2281 gtattgatgg tgaaacagcc aaattaaaaa tagaagcttt aaaaaaagaa atggaagaga
     2341 ttgaaaataa aattcaagag ttaaaaggaa ataaagcaaa aaaaacaaat aaagaagaaa
     2401 ataatgtttc agaagtaaat aataatctat tagagagaaa aaaagaacct tctaataatg
     2461 aaaatgtaaa acaattatat gatgtttttg aaagaagcaa tgtagacgaa caatgggata
     2521 atacttatcg tgttctccaa gatgataaaa acttaaaagt aaaatttaat agacctatat
     2581 agtttattta taaaaatagt taatatttta attatcacca ctttttagaa gaatacacac
     2641 tttattttaa agacccacat atttatttac agttagcaca tttatatgtg gttttataac
     2701 tattatttac aagtctatat tgataacttt tacatagtat ataatgttta aatacttatt
     2761 caaatttatc tatacataaa caaaaaaaga gattttaaaa tctcttttta gattgttgac
     2821 ttatggcttt ttgatttaat aaaatcaaga agccgtttga attttatctg ttggctgata
     2881 cccttctgat attgaaacac catttttgtt tccaaaatcg tttaaaatta agaacttatt
     2941 atgaatgact atttcattat gaacaataag cagataacat gaatcttcaa tcaatgtttt
     3001 aacagtagca ttaaatgctt gcttatacag ttctatcgtt tgtttgaact gtccattaaa
     3061 gtaaatatga gtcaataaca taactatatc tacacaaatt aatataaatt ttttatactg
     3121 tacattatct aactgttgat tatctgtatt acaacatgat tgaatttaaa aagccatcaa
     3181 cacatagaat gttgatggcc tgaaaataga tttaaaatct cttttttatt atatattaat
     3241 tattttttaa atttatattt tttgcatcag attttctaat agctaagtca aaccctctaa
     3301 atctaatcac tatagggtca ttaagaggag ctatcttttt cacttcaact tcagtgccat
     3361 ctattagtcc taaggctaga agtctcttca taagtttttc atttccagct atattgtcta
     3421 taattccctt ttgtccaagt tttaagttgt aaacagtcat tattaacacc tcctaatgaa
     3481 aatcattatc aaactttata tttataatat ataacaaaaa gagcaaattg tcaatatata
     3541 acaaaaaata aacatactaa gttagtatgt ttataaaaaa tagtatacat gggatactaa
     3601 tagcatctag caaaaaacca cttactaatg gtacaactaa aaaggctttt ggagaatcac
     3661 catatttttg tgtcaaagaa ctcatatttg ccagagcgtt cggagtagct cctattccat
     3721 gtccaatcaa accacttatt atgatggcag aatcaaaatc ttttccaagt actctaaagc
     3781 aaataaatat tgaaaatagg attataaaga ttacttgaaa agttactatt aagagaatag
     3841 gaggtaataa tgtagataat tcaaataaat ctatattcat aagtgataaa gttaaaaaaa
     3901 ttcccaatga aagttctttt aaaaaatcta taagtttaaa atttaattct agtatattta
     3961 tcttatcatt taaatttcta aaaataacag ccg
//
LOCUS       DAEPKC010000173         3931 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.176, whole genome shotgun sequence.
ACCESSION   DAEPKC010000173 DAEPKC010000000
VERSION     DAEPKC010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3931)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3931)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3931
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.176"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            308..997
                     /locus_tag="KR294_003630"
     CDS             308..997
                     /locus_tag="KR294_003630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0241672.1"
                     /translation="MDILLVEDDKNIREMVYDFLISENYSVKTAIDGNTAIEIFKNYS
                     FDIILLDLMLPKSSGFEVLKYIRSVSVVPVIITTAKDSDTDKMLGLNLGADDYITKPF
                     SIVELLARIKANIRRATVYSSSRNSQDMVIRYKDLIINISKYVVSKNGIDLNLTHTEF
                     EIVKLLATNQGRAFSKEQLYNAIWKEPYYGNENVLNTHINRLRNKLSDGIEKNNYIKT
                     LWGIGYKMEEE"
     gene            997..1914
                     /locus_tag="KR294_003631"
     CDS             997..1914
                     /locus_tag="KR294_003631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBH0241673.1"
                     /translation="MELFLVVISIVLFALYLKERNKSKKMESDYKYINSRLRDITNDD
                     EINYILVPSDISIVKETAVDINKLVEKFYSRQINYNRSEKAILQIFTNISHDLRTPIT
                     VLKGYIEMLYLQSQKEELSSSMRAIVEKMQTNSNELVNSINNLFNMAKIQSGDMILNL
                     QKSNLTQLCHEIILEFYDLLDKENFNVEVNIEDRPIYANVDTEALQRILKNLIDNAIK
                     YGSDGRFLGISLYEKEKHVFIDIEDKGSGISETEKEHIFTRAYTADRKKGNGLGLAIS
                     QGLANSMGGSIYVNSRPNVKTVFTVKLKS"
     gene            1987..2913
                     /locus_tag="KR294_003632"
     CDS             1987..2913
                     /locus_tag="KR294_003632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0241674.1"
                     /translation="MNYIIETHQLKKIYKDKAVVNAVNIHVKKGEIYGFVGPNGAGKS
                     TVMKMLLNLVNPNSGEIVMFGKKVAETDFEILKKIGTIIENPYLYENLTAKQNLDLHC
                     EYMGYYNKEHISEVLECVGLSKQSNKKVSKYSLGMKQRLAIARAILTKPELLILDEPI
                     NALDPEGIREMRELFRKLNTDYGITIFISSHILSEVEQIADTIGIIQDGKLIKEISMS
                     DIHKYQTDYVEVDVDNVELAGYLLEKEFGIKDFKITSESCIEIYDLRKDVKEISKIFI
                     QNQIGINSIGRKQSSLEDYFFQTTGTGGKETL"
     gene            2910..3590
                     /locus_tag="KR294_003633"
     CDS             2910..3590
                     /locus_tag="KR294_003633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0241675.1"
                     /translation="MIHLMKLELKKVGLKRYFLFSMLGIFLCMFFVFTGLNDKSTSIY
                     DYDVTFRTISLFFCFYYIILFAVLNVAYIINEYTNKTILILFSYPLDRKKLILSKLLL
                     ITTLMISSMIVGYICCFTFVVVLDKYFNLVIGDFHISILSYWIPGAIKSIIVFCSLGI
                     WTFVVGMIRKSIPVTLVSSIIFINLRQFILAGTNTTQDSLISVFIIVGITVIGIYYIL
                     NHKVTEID"
     gene            3688..3931
                     /locus_tag="KR294_003634"
                     /pseudo
     CDS             3688..3931
                     /locus_tag="KR294_003634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427885.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
BASE COUNT         1490 a          417 c          666 g         1358 t
ORIGIN      
        1 tgtataaaac tagaatgtgg tttctttttt atgtataaaa tattttttag caaaagttaa
       61 aaggtgtttt ataatataaa atagttaatt gtagatgtta ataaaagaaa attatgtata
      121 ttttagataa agataagaga gtatactata ttttaattct tttttcaata aagcttattg
      181 aaaagaactt taacttagaa gagtatcacc aaattgcaga tacaatatca taagcagtta
      241 tttattgaca acccttttta ataaatatat catttgaagt atactgacga aaaggagttg
      301 aataataatg gacatcttat tggttgaaga tgataagaat attcgagaaa tggtatacga
      361 ttttctgatt agtgagaatt actctgttaa aactgccatt gatggaaata cagctattga
      421 aatatttaaa aattattcat ttgatattat tttactggac ttgatgttac caaagtctag
      481 tggttttgaa gtattaaaat atatacgaag tgtgagtgtt gttcctgtta ttattactac
      541 tgcgaaagat agtgacacag ataaaatgct agggcttaat ctaggtgcag atgattatat
      601 tacaaagcct ttttcaatcg tagaattgct tgcaagaatt aaagctaata ttagacgtgc
      661 aacagtgtat agcagttcaa gaaactctca agatatggtt attcggtata aggatttgat
      721 tataaacata tcaaaatatg tagtttcaaa gaatggaatt gacttaaact taacacatac
      781 agaatttgaa attgttaaat tactagcgac taatcaagga cgtgcttttt caaaggaaca
      841 attatacaac gctatttgga aagaacctta ttatggaaat gaaaatgtgc taaatactca
      901 tattaacagg ttaagaaata aattgtctga tggtatagaa aaaaataatt atattaaaac
      961 tctttgggga attggctaca aaatggagga agaataatgg agttattttt agttgtaatt
     1021 tcgattgtac tatttgctct ctacttaaaa gaacgaaata aatcaaagaa aatggaaagt
     1081 gattataagt atatcaattc aagacttcgt gacataacaa atgatgatga aattaattat
     1141 attttagtac catctgatat ttcgattgta aaagaaacag cagtagatat aaataaactt
     1201 gttgaaaagt tttacagcag gcaaattaat tataatagaa gtgaaaaagc gatattgcaa
     1261 atatttacaa acatatcaca cgatttacga actcccatca cagtattaaa gggttatatt
     1321 gaaatgctat atcttcaaag tcaaaaagaa gaattatctt cttcaatgag agcaattgtg
     1381 gaaaaaatgc aaacaaattc aaatgagctt gttaattcaa taaataacct gtttaatatg
     1441 gcaaaaatcc aatctggaga tatgatatta aatcttcaaa aatccaatct aacacaatta
     1501 tgtcatgaga ttattttaga gttttatgat ttgctagata aagaaaactt taatgttgaa
     1561 gttaatattg aagatagacc tatatatgca aatgttgaca cagaagcatt acaacgtata
     1621 ctcaaaaatt taattgataa tgctataaaa tatggttcag atggtagatt tttagggatt
     1681 tcactatatg aaaaggaaaa acatgttttt atagatattg aggataaagg ttcaggtatt
     1741 tctgaaactg aaaaagagca tattttcaca agagcttata ctgctgacag aaaaaaaggc
     1801 aatggtttag gtttggctat ttctcaaggg cttgcaaact ctatgggagg ttcaatttat
     1861 gtaaatagta gacctaatgt aaaaacagtt tttacggtaa aattgaaaag ttagaaaaaa
     1921 gttagattta aaagagagaa aagacaattt tattttgtat actgttttta gaaaggaggg
     1981 agtatgatga actatatcat agagacccat caattaaaga aaatatataa agataaagct
     2041 gttgttaatg ctgttaatat tcatgtgaaa aagggagaaa tttatggatt tgttggacca
     2101 aacggggcag gtaaaagtac agtaatgaaa atgttgctaa atcttgttaa tccaaattct
     2161 ggagaaatag ttatgttcgg taagaaagtg gcagaaactg attttgaaat attaaaaaag
     2221 attggtacta ttattgaaaa tccgtattta tatgagaatt tgactgctaa acagaatctt
     2281 gatttacact gtgaatatat gggttattat aacaaagaac atatatcaga ggtattggaa
     2341 tgtgtcggat tgtcaaagca atcaaacaag aaagtttcaa aatattcttt agggatgaaa
     2401 caacgtcttg caatagctag agcaattctt actaaaccag aattattgat tcttgatgaa
     2461 cctataaatg cactcgaccc agaggggata agagaaatgc gagaattatt ccgtaagtta
     2521 aatacagatt atggaataac tatatttatt tctagtcata ttctttcaga ggtagaacaa
     2581 attgcggaca ctattggaat tattcaagat ggtaaactta ttaaagaaat ttctatgtca
     2641 gatatacaca aatatcaaac agattatgtt gaagtagatg tagataatgt ggagcttgct
     2701 ggatacttgt tagaaaaaga atttggaata aaagacttta aaattacttc ggaaagttgt
     2761 attgaaatat atgatttacg aaaagatgta aaagaaatat ccaaaatatt tattcaaaat
     2821 caaattggta taaatagcat tggacgtaaa caaagttctt tagaagatta cttcttccaa
     2881 actacaggta caggaggtaa agaaacacta tgatacattt aatgaaacta gagctaaaaa
     2941 aagttgggct aaaaagatat tttttatttt caatgctggg gattttctta tgtatgtttt
     3001 ttgtctttac tggattgaat gataaatcta cttcaatata tgattatgat gttacattta
     3061 ggacaatcag tttatttttc tgtttttact atattatatt atttgctgtg ttgaatgtgg
     3121 catatataat aaatgaatat acaaataaaa caatcttgat tttattctct tatccacttg
     3181 accgtaaaaa acttatttta tcaaagttac ttttgattac gactcttatg atatcatcaa
     3241 tgatagttgg atatatctgt tgttttacat tcgttgttgt gttggataag tattttaatt
     3301 tagttattgg agattttcat atttcaattt tatcttattg gataccagga gcaattaaaa
     3361 gtattattgt attttgctca ttaggtatat ggacattcgt tgttggaatg ataagaaaat
     3421 caatacctgt tacccttgtc agttcaatta tttttatcaa tttaagacaa tttattttag
     3481 ctggtacaaa tacaactcaa gacagtttga tttctgtttt tattatagtt ggtataactg
     3541 tgattggtat atattatata ctaaatcata aagttactga aattgactag atactgtgga
     3601 taggagggta gttattaatt gtatcttctt gggataataa tgatttgcta ttatatcagc
     3661 tattattaat attattagag ttttaataat attgcacaac catttgaagt tgagccaaag
     3721 cttgatgaat taattgaatg gtactatagt cagagtgaag tatctattaa agttatagct
     3781 gaatttcatt atagatttga attgatacat ccatttcaag atggtaatgg tcgcataggt
     3841 agatttgtta tgctaaaaca gatgttagaa aataatcttc ctataaaaat tgtatcttgg
     3901 gatagtgagg aattgtatag aaactcctta a
//
LOCUS       DAEPKC010000174         3658 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.177, whole genome shotgun sequence.
ACCESSION   DAEPKC010000174 DAEPKC010000000
VERSION     DAEPKC010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3658)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3658)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3658
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.177"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(81..413)
                     /locus_tag="KR294_003635"
     CDS             complement(81..413)
                     /locus_tag="KR294_003635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HBH0241676.1"
                     /translation="MNTREMKEYRGFYNKKLSETDEFFRVFGSLDDKTYSEGAISKKN
                     KELMGLAISILSRCDECICYHIEGCINSGASKDEIIEAIKIGVIGGGSITYPNARFAI
                     KILEEFNI"
     gene            complement(657..1298)
                     /locus_tag="KR294_003636"
     CDS             complement(657..1298)
                     /locus_tag="KR294_003636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HBH0241677.1"
                     /translation="MKKAINKQFILSTLICFIPFIVSIYFYNRLPNEVAIHFDNYGNP
                     DNYAPKVIAAFGVPLLMLCIHLYTWFRLENEPKKANFSNVIQNLSKWGVAILSVIIQI
                     MMVLYSTGVSLESNFYTGLILGIIVILFGNYLPKCKRNYSVGIILPWTLNDEDNWNKT
                     HHLAGWIWLIGGILLIINAFINIPFYNIFVIFVIVILPFVYSYLMYKISGKNN"
     gene            complement(1279..1572)
                     /locus_tag="KR294_003637"
     CDS             complement(1279..1572)
                     /locus_tag="KR294_003637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBH0241678.1"
                     /translation="MGFPETFKALSDPIRREILVMLRENKMSAGEISEKFNMTNATIS
                     YHLSQLKKAGLIFETKYKNFIFYEINISVFEEVMLWFSQFMEKGEKDNEKSDK"
     gene            1965..2015
                     /locus_tag="KR294_003638"
     CDS             1965..2015
                     /locus_tag="KR294_003638"
                     /inference="COORDINATES: protein motif:HMM:NF024729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241679.1"
                     /translation="MTEYIYYYNNKRIKKN"
     gene            complement(2541..3293)
                     /locus_tag="KR294_003639"
     CDS             complement(2541..3293)
                     /locus_tag="KR294_003639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TSUP family transporter"
                     /protein_id="HBH0241680.1"
                     /translation="MFSVIFLCIGGFLAAFVDSIAGGGGLISMPVLMAIGVPVHLAIG
                     TNKFAASAGCISSAYRYAKSGKINNNLLKKLVPFTIIGSVLGVRCVLSISEEILNVLV
                     VAMILIVAIYTFISKNLGQEDNFEAVNKKNLRLGMLMALIMGFYDGFFGPGTGTFLTF
                     GFIKIYGYDFLHASANTKILNLTSNITSLLLFMINGQVDYKIAIVFALVMIMGAYVGA
                     KVAIKKGSKMIKPIFLVMALFMVVKLVYQTLV"
     gene            complement(3352..3621)
                     /locus_tag="KR294_003640"
     CDS             complement(3352..3621)
                     /locus_tag="KR294_003640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007064919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH0241681.1"
                     /translation="MNSISDVFFISPNYLSSIFNERNKVSITEYINLLRIEESKKYLL
                     DRSMSVSDICKKVGFNNSSYFSQIFKKFNSITPNEYRKNMLDNKY"
BASE COUNT         1352 a          584 c          324 g         1398 t
ORIGIN      
        1 tgaacttaga aaataaagct taatttcaaa ggcttaaata gactattatt attagtctaa
       61 ataaactacg tgtatcaaaa ttatatatta aattcttcta aaatttttat tgcaaatctt
      121 gcgtttggat atgtaataga ccctccacca attacaccta tttttatagc ttctataatt
      181 tcatctttac ttgctccaga attaatacaa ccctcaatat gataacaaat acactcatca
      241 catcggctta aaattgaaat agctagtccc attaattcct tatttttttt acttatagcc
      301 ccttctgaat aagtcttatc atcaaggctt ccaaatactc taaaaaactc atctgtttca
      361 cttaattttt tattgtaaaa tcccctatat tctttcattt ctctagtatt catcttctac
      421 ctcctatttt tttcttataa gagtatcaca ctgtacttat attttcaata ttaaatacaa
      481 attttcattt tatgttcatt agcctaattt atattatttt ttgaaatctc aataagttat
      541 catataagta agattttttc agaactaaaa tagaaatctc agtaatttct ttattatcta
      601 tctcagttct gaaatatatt attcttatcc aaacattatt atagtgatta attatattag
      661 ttatttttac ctgaaatttt atacatcaaa taagaatata caaatggtag tattacaatt
      721 acaaagatta caaagatatt ataaaaagga atattaataa atgcattaat aattaataat
      781 attccaccaa taagccaaat ccatccagct aaatggtgtg tcttattcca attatcttca
      841 tcattaagag tccatggtaa aattattcct actgagtaat ttcgtttaca tttaggaaga
      901 tagtttccaa ataaaataac tattattcct aaaattaatc ctgtataaaa attagactcc
      961 aaactaactc ctgttgaata taaaaccatc attatttgta taattactga aagtatagca
     1021 actccccatt ttgataaatt ttgtataaca tttgaaaaat tagctttctt aggctcattc
     1081 tcaagtctaa accatgtata caaatggata catagcatta acaatggtac accaaaagct
     1141 gctataacct ttggagcata attatctgga tttccataat tatcaaaatg aattgcaact
     1201 tcatttggta atctattata aaaatatatt gatacaataa atggtataaa acatattaaa
     1261 gtagataaaa taaattgttt atttatcgct tttttcatta tctttttctc ccttctccat
     1321 aaattgcgaa aaccaaagca taacctcttc gaaaactgaa atatttattt cgtagaaaat
     1381 aaagttctta tactttgttt caaatatgag tcctgccttt tttagttgag atagatgata
     1441 agaaattgta gcattcgtca tattaaattt ttcactaatt tctcctgctg acattttatt
     1501 ctccctcaac ataaccaata tttctcttct tatagggtct gaaagagctt tgaatgtttc
     1561 tggaaacccc aacaccatca cctcgctatt tagaatttca tctaaataga atataacata
     1621 acatccattt tatttcaata actatttaga attttttcta aatagttatt tctaaatatt
     1681 tattgaaaat tttcatatta agattctcaa tttacttaag tcgcttttat ttaatcttac
     1741 tttatctaat ttttttaact taacaaaagt gtattgcacc ataattgtta aagcaaaaac
     1801 ctaatgactg aggtacttat atatataaca atacttttaa ttttaaatta aaagtagcta
     1861 aacccaattt aaaaagtagt taagtcctat ttaaatagaa aagaatgaaa cgagaaatat
     1921 actgtataaa agtacataaa aacatctact aattagatac aactataaca gaatatattt
     1981 attattataa taacaaaaga ataaaaaaaa attaatttag catagccttg ttaaatatag
     2041 atttgaatat gaatttaaag ttatgtaaaa ttaaaaatac aggaatgaaa attccattcc
     2101 tgtataaaat ctaacttttg agtctcagta caatcttatt ttgagacaat cttttttgtt
     2161 ttatattttc ttatatttaa aatataacgc atatcttatg caacatattc atatttttct
     2221 ttatattctt tcatcgcatc attccaagcg tcttgtactg ttacacctct tttattagca
     2281 attttttgtg ccagttcaat tatcttcata gctcttcttg atatgttcat aaacattcct
     2341 cctacaaatt accatatatt tcatatatat aaatcaaggt tatattttta tgatatataa
     2401 tccttctatt gtaagattac agtttatatg tgtattatat atgaactata ttagaagata
     2461 attagaattt ttataaagct atatgattag attaaatata aaagctttac aattacttat
     2521 aaatttaaaa agtctataaa ctaaactaat gtttgatata ccaattttac gaccataaat
     2581 aatgccatta ctaaaaatat tggttttatc atctttgaac ctttctttat agcaacttta
     2641 gcacctacat aagctcccat tatcatcact aatgcaaaca ctatagcaat tttataatct
     2701 acttgaccat ttatcatgaa taataacaat gaagttatat tacttgttaa gtttaatatt
     2761 tttgtatttg cagaagcatg taaaaaatca tatccatata tttttataaa tccaaaagtc
     2821 aaaaaagttc ctgtacctgg accaaaaaaa ccatcataaa aacccattat aagagccata
     2881 agcatcccta gtcttaaatt tttcttatta acagcttcaa aattatcttc ttgacctaaa
     2941 tttttagaaa taaaggtgta aatagccact attaaaatca tagccacaac caaaacattt
     3001 aatatctctt cacttattga taatacacat ctcacaccta gaacactacc aataatagta
     3061 aatggtacta atttttttaa aaggttgtta ttaatttttc cagactttgc atatctatag
     3121 gcactactta tacatcctgc tgatgctgca aatttatttg taccaatggc aagatgtact
     3181 ggcactccaa ttgccataag aacaggcatg cttataagtc ctcctcctcc tgctatagaa
     3241 tctacaaaag cagctaaaaa cccccctata cataaaaaaa taactgaaaa cataaaattc
     3301 ctccatcatt ctctttcaat ttttcttaca atatatatta tataatctta tttaatactt
     3361 attatccagc atattctttc tatattcatt tggagttata ctattaaact tcttaaatat
     3421 ttgtgaaaaa taactactgt tattaaaacc tactttctta caaatatcac taacactcat
     3481 gcttctatct aacagatatt ttttagattc ttctatccta agaagattta tatactcagt
     3541 tattgaaact ttatttcttt cattaaaaat agaactcaaa taatttggac ttataaaaaa
     3601 aacatctgat atactattca aatttatatt ttctttataa tattttttta tatattcg
//
LOCUS       DAEPKC010000175         3644 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.178, whole genome shotgun sequence.
ACCESSION   DAEPKC010000175 DAEPKC010000000
VERSION     DAEPKC010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3644)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3644)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3644
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.178"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(134..514)
                     /locus_tag="KR294_003641"
     CDS             complement(134..514)
                     /locus_tag="KR294_003641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBH0241682.1"
                     /translation="MCLKKLSKLELVIMKFIWNLDIKTNSYEIIDYMKEEHNLPEKVA
                     LKTLSKLSKKRFLYVQETGKCMYYTVAIKEKAYLEFISRNVQNLLKNNFIRNLLVSFH
                     EEELTEEKIKSLENWVVNWEEAYV"
     gene            complement(715..1908)
                     /locus_tag="KR294_003642"
     CDS             complement(715..1908)
                     /locus_tag="KR294_003642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HBH0241683.1"
                     /translation="MLTSLALIFLLGMASGGIFKRIKLPNLLGMLLTGIILGPYVLNL
                     IDNSILDISSDLRKIALIIILTRAGLSLDINDLKKVGRPAVLMCFIPATFEIIGMIVL
                     APKLLGVSILEAAVMGAVVGAVSPAIIVPKMLKLMEEGYGTEKSIPQMLLAGTSIDDI
                     FVIVMFTVFTGLAQGNSISAISFLQIPVSIILGVIVGAVIGIYLAVFFKKVHMRDSAK
                     GVLLLSISFLMISLETALEGIVPFSGLLAVMSIGIFLQIKYRVVARRLSIKYSKLWVG
                     AEILLFVLVGATVDISYAFKAGIGAVILIFGVLLFRMVGVFFCLIKTNLTIKERLFCM
                     IGYIPKATVQAAIGGVPLAMGMASGQLILTLAVLAILITAPLGAFGIDVTYKKLLTSV
                     KGENK"
     gene            complement(1971..3227)
                     /locus_tag="KR294_003643"
     CDS             complement(1971..3227)
                     /locus_tag="KR294_003643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HBH0241684.1"
                     /translation="MIEKFKTLIWIKMIIRIKSVYKTYGGLFFLGLIGIPVGAIIGLI
                     DTIFGTVLLKVTDIRETYPMYLIPFLAVVGVVIAYCYFKFGGKSSKGMNLIFEVGHGE
                     EEIIPLRLVPFIISGTWLTHLFGGSAGREGVAVQIGATFSHWVGKRLPIKNASSIFLV
                     TGMAAGFAGLFETPIAAILFAMEVLVAGSLEYQSLFPAFTASFTASAVSKALGLEKFS
                     FALSSKVVFDLSIFWKLIVLGIIFGMVGGAFAWCLKLSKRKIGNRLKNPMIRIAIIGV
                     CLSVLFLLFYKGRYSGLGTNLIQNSFYGGEIYSFDWLLKFILTILTLSAGFQGGEVTP
                     LFSIGASLGVLLAGFFNLPIELVAALGYASVFGSATNTFFAPVFIGAEVFGYSYLPYF
                     FVVCAISYIFNMDKSIYSLQKISTKQ"
BASE COUNT         1320 a          700 c          387 g         1237 t
ORIGIN      
        1 taaatataaa tgcgtttact tttaagtatt gcttaaggga ataaaaaata aaaataaact
       61 ctgcaaccat ctaaaaatag ttgcagagct tacaaaacca aaattatcta aattgtaata
      121 aaaataataa catttataca taagcttctt cccaatttac tacccagttt tctaacgact
      181 ttatcttttc ctctgttagc tcctcttcgt gaaatgatac taataaattc cttataaaat
      241 tattcttcaa aagattttgc acatttcttg atataaactc taaatatgcc ttttctttga
      301 ttgcaactgt ataatacata cacttgcctg tttcttgaac atataagaat cttttctttg
      361 atagttttga taaagttttt aaagctactt tttctggtaa attatgttct tctttcatat
      421 aatcaataat ctcatatgaa ttggttttta tatctaaatt ccaaataaat ttcataataa
      481 ctaactctaa ttttgataat ttttttaaac acatagttat cactccgctt ctttatctat
      541 ataattaaat attacaataa taatttcaca aaatcaattc taataatcat aacatacctt
      601 aaaatctgtt cttaacttct accttcttaa tctcccaaat gattttttta tattgtattc
      661 aatagtataa tccttttcca aaatataact taccagttaa aataatcttt atttttactt
      721 attctcgcct tttacagaag ttaataattt tttataagtt acatcaattc caaaagctcc
      781 aagaggtgca gttataagta tagctagaac tgctaacgtc aaaataagtt gtccagatgc
      841 catccccatt gcaagtggta cacctcctat tgccgcctgt actgtagcct ttggaatata
      901 gccaatcata cagaacaatc tttcctttat tgtcaaattt gtcttaataa ggcagaagaa
      961 tactcctacc atacggaata aaagaactcc aaatattaaa attacagctc caattcctgc
     1021 tttaaatgca taacttatat ctactgttgc ccctaccaaa acaaacaaga gaatttcagc
     1081 accaacccat agtttcgaat actttataga caatcttctt gcaactacac gatattttat
     1141 ctgaaggaaa atcccaatac tcataactgc taataatcca gaaaatggca caataccctc
     1201 taaagcagtc tctaaactta tcattaaaaa tgagatactt aaaagcaaca cccctttagc
     1261 agaatctctc atatgaacct tcttaaaaaa tactgctaaa tagattccaa tcactgctcc
     1321 aactattaca cctaatataa ttgatactgg aatttgtaaa aagctaatag ctgatatact
     1381 atttccttgt gccaatcctg tgaatactgt aaacatcaca attacgaaaa tatcgtctat
     1441 agaagttcct gctaaaagca tctgtggaat acttttttct gtaccataac cttcttccat
     1501 taatttaagc attttaggta caataattgc gggagaaact gctcctacta ctgcacccat
     1561 gactgctgct tccaatatag aaacgcctag taactttggt gctaaaacta tcattccgat
     1621 aatttcaaaa gtagctggaa taaagcacat aagtacagcg ggtcttccca ctttcttcaa
     1681 atcgtttata tctaaagata atccagccct tgttaatata ataatcaatg caatctttct
     1741 aaggtcagaa gaaatatcta gtattgaatt atcaatcaaa tttaaaacat atggacctaa
     1801 tataattccc gtaagtaaca ttcccaataa gttaggtaat tttatcctct taaaaatacc
     1861 tcccgaggcc attcctaata aaaaaatcaa agctaaactt gtcaacatat tcctacccta
     1921 tcctttctct aatattcttt ctcttctaat catacattat gttgttttat ttattgtttt
     1981 gttgaaattt tttgtagtga ataaatagat ttatccatat taaatatata tgaaatagcg
     2041 catactacaa agaaataagg taaatagctg tacccaaaaa cttctgcccc tataaataca
     2101 ggtgcaaaaa aagtatttgt agcactacca aagacactag catagccaag cgctgcaact
     2161 aattcaattg gcaaattaaa aaatcctgct aacaatacac caagactagc tccaatggaa
     2221 aacaaaggtg taacctctcc tccttgaaaa cctgctgaca aagtcagtat tgtaagtata
     2281 aactttaaca gccagtcaaa tgaataaatt tctccaccat agaaactatt ttgaattaaa
     2341 tttgtcccta aacctgaata tcttccttta taaaataaaa ggaataatac actaagacat
     2401 actccaataa tagcaatcct tatcatagga ttttttaatc tattccctat ttttcttttt
     2461 gacaatttca gacaccatgc aaatgctcca ccaaccattc caaaaataat tcctaaaaca
     2521 ataagcttcc aaaatattga caagtcaaat acaactttag aagaaagtgc aaaagaaaat
     2581 ttctctaacc ctaaagcttt tgatactgca cttgctgtaa aagaagcagt aaacgcagga
     2641 aaaagcgatt gatactccag tgaaccagca accaaaacct ccatagcaaa tagtattgct
     2701 gctattggtg tctcaaataa tcctgcaaaa ccagctgcca taccagttac tagaaaaata
     2761 ctagaagcat tttttatagg caacctttta cctacccaat gtgaaaaagt tgcaccaatc
     2821 tgaacagcaa ctccttctcg tcctgcacta ccaccaaata aatgggttaa ccatgtacct
     2881 gatattataa atggaaccaa tcttaaagga ataatttctt cttctccatg ccctacctca
     2941 aatattagat tcattccttt actacttttt cctccaaatt taaaatagca ataagcaata
     3001 acaactccta ctactgctaa aaatggtatc agatacattg gatatgtttc tcgaatatct
     3061 gtaactttta gaagaaccgt tccaaatatg gtatctataa gacctataat tgcaccaact
     3121 ggtataccta tgagtcctaa aaaaaatagt ccaccatatg ttttataaac gcttttaatt
     3181 cttattatca ttttaatcca tattaaagtt ttaaattttt ctatcatttt aattcctttc
     3241 tatttgcatc ataagatttt ttgaaagttt tattacatca actgtagtca atgtaatgac
     3301 tatcataatt gttttttaaa ttgataggat ataggtacac tcttaaccca ttcttaataa
     3361 aataattaac atataatcta ctattttttc tattaattaa atatttcttc aaatttaaaa
     3421 aataaaaatt tagtaagtac ttcacctcca ttttatcgat ttaaacaaca aaaaaagctg
     3481 gtggcatcta tgatatcata gaagtcatca gctcattggc agtttaggat attatcatcc
     3541 aagggagaac ctcattccca taattattat ataatttttt atttttcata tgtctatttt
     3601 atgtaaattg tatttttaat gttataaata atataaccta tcaa
//
LOCUS       DAEPKC010000176         3631 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.179, whole genome shotgun sequence.
ACCESSION   DAEPKC010000176 DAEPKC010000000
VERSION     DAEPKC010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3631)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3631)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3631
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.179"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            25..777
                     /locus_tag="KR294_003644"
     CDS             25..777
                     /locus_tag="KR294_003644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0241685.1"
                     /translation="MKEILKIKNISKDYGIKGFKTNVLKNISLTVNEGDFISIMGPSG
                     AGKTTLLNLMSTLDKQTSGEIILDGINISKVKNNELSKLRREKIGFIFQDYNLLDNMK
                     LMDNIALPLALGKKKSKEIEAKVFSIAKKFGLENHLDKYPYQLSGGQKQRGAAARSLI
                     TNPTVIFADEPTGALDSKSAYELLESLEKINRENNATIIMITHDPLTASYSNEVYMIN
                     DGNIKCKLNKGNSRKEFYGKIMDMLASMGGEM"
     gene            778..2685
                     /locus_tag="KR294_003645"
     CDS             778..2685
                     /locus_tag="KR294_003645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HBH0241686.1"
                     /translation="MSILGIAYNNFKSNIRTYLAFFISMVFSVVVLTNFELLRYGDAI
                     NVLQEENKKFTLSVLVAVIMILSVFLFFFIWYATNIFFKNRSKEIGILSFMGLDLYTI
                     GKIYFVENMLIGISSCITGIIIGIITSRFFQVVIIKLSGFNIKVSNGLSIEAILYATL
                     IFISIFIIMAVKGFITICRSSVINLINISKKQEKIPKVGIGIYILAIVSIIVIGYGYY
                     LSTNIRTGDITSVLPVIGIIIVGTYGLFKSVMPVIFDIIIKNKKILFNGNNIIAINNI
                     NYRLNKNYKTYAIIAIIITTTISTLGASVAMKHIHKNAQEQRNVYTISIVSMDKDEVN
                     KKQIENIIKDTNKIKYSVNPELTILKKTDIKEAYDTTDTIMKYSDFCNTLKVNGNDKE
                     LKEYGERLVSGNNVIELKSPQTIASIATKEAKIKLDGQLYNISRGEVKVPVLGTGLNQ
                     SIIVVNDDTYFKLRDKGQQVYFYGAKVFQEENSQVMFNNIEKNLSLKNGYIQNGYKAQ
                     GESQWMKFAYVVLVFLFLVFAIVAGSIIYMKIYSDAYEDKEKYKILLKIGTTEKDINR
                     AILKEVAIFYTLPMLSATISSYFALRLAGDLLMTDLFGIYILSLVICLIIFIIYGAVS
                     VNKFKSVVYKN"
     gene            2837..3517
                     /locus_tag="KR294_003646"
     CDS             2837..3517
                     /locus_tag="KR294_003646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0241687.1"
                     /translation="MYRILLVEDDIDLSKEIALALEKWGFKVELIDDFEVVLDEFIDK
                     KPDVVLLDVNLPLYNGFYWCEKIRAISNVPLIFLSSRDSDMDLIMGINNGADDYITKP
                     FSIEILVTKINGIIRRVYNYSDSNSILYCEDLMFDVGKGIIKHKYKDKSIELTKNEIK
                     ILTLLLKNKNRVVSRESLMMTLWDNDEFVTDNALTVNMNRLRSKVKELGFDDFIKTKK
                     GIGYIIQC"
BASE COUNT         1511 a          324 c          613 g         1183 t
ORIGIN      
        1 aattagcaac tggaggctat tgttatgaaa gaaatattaa aaataaaaaa tatatcaaaa
       61 gattatggaa taaaaggatt taaaacaaat gtattaaaaa atatatctct tacagtcaat
      121 gaaggtgatt ttatatcaat aatgggtcca tctggtgcag gaaagacaac attgctaaat
      181 ttaatgtcta cacttgacaa acaaacttca ggagaaataa tactagatgg aattaatata
      241 tcaaaagtaa aaaataatga actatcaaaa ttaagaagag aaaaaatagg gtttatattt
      301 caagactata atctattaga caatatgaaa ctaatggaca atatagcact tcctctagca
      361 ttaggaaaaa agaaaagtaa ggagatagaa gctaaggtat tttctatagc taaaaaattt
      421 ggattagaaa atcatttaga taaatatcca tatcagttat caggaggaca aaaacaaaga
      481 ggcgcagcag ctaggtcatt aattacaaat ccaacagtca tatttgctga tgagccaact
      541 ggtgctttag actctaaatc agcatatgaa cttttagaat cattagaaaa aataaacaga
      601 gaaaataacg ctactattat aatgattaca catgaccctc taacagcaag ttattcaaat
      661 gaagtatata tgataaatga tggaaatata aagtgtaaat taaacaaagg aaatagtaga
      721 aaagaatttt atggaaaaat tatggatatg ctagcctcta tgggaggtga gatgtaagtg
      781 agtatacttg gaattgctta taataatttt aagagtaaca taagaactta tctagcattt
      841 tttatatcta tggttttttc agtagttgtg ctaactaatt ttgaattatt aagatatggt
      901 gatgctataa atgtgttaca agaggaaaat aaaaaattta cactatcagt gttagtagct
      961 gtaataatga tactatcagt atttttattt ttctttatat ggtatgcaac aaatatattt
     1021 tttaagaata ggtctaaaga aattggaata ttgtctttta tgggattaga tttatatact
     1081 ataggaaaaa tatattttgt agaaaatatg cttataggaa taagttcttg tataacagga
     1141 ataattatag ggataataac atctagattt tttcaagtag tgataataaa gttatctgga
     1201 tttaatataa aggtatctaa tggacttagt atagaagcta tactatatgc tactttaatc
     1261 tttatttcta tatttataat aatggctgta aaaggtttta taacaatatg tagaagtagt
     1321 gtaataaatc taatcaatat atctaaaaaa caagaaaaaa taccaaaggt aggaataggt
     1381 atatatatat tagctatagt atcaattata gtaataggat atggctacta tctttctacc
     1441 aatataagaa ctggagatat aactagtgta ctacctgtta taggtataat aatagtaggt
     1501 acttatggat tattcaaatc agttatgcct gttatatttg atattataat caaaaataaa
     1561 aaaatattat ttaatggaaa taatataatt gcaataaaca atataaacta ccgattaaat
     1621 aaaaactata aaacttatgc tataatagct ataattataa ctacaacaat atcaactctt
     1681 ggtgcttcag ttgctatgaa gcatatacat aagaatgccc aagaacaaag aaatgtgtac
     1741 actattagca tagtttcaat ggataaagat gaagtgaata aaaaacaaat agagaatata
     1801 ataaaagata ctaataagat aaagtactca gtaaatccag aactaacaat tttaaagaaa
     1861 acagatataa aagaagctta tgatacaaca gatactataa tgaaatatag tgatttttgt
     1921 aatactctta aagtgaatgg taatgataaa gaattaaaag agtatggtga aagattagtt
     1981 agtggaaata atgtaataga gttaaaaagc cctcaaacga tagcatcaat agctacaaaa
     2041 gaagccaaga taaaacttga tggtcagtta tataatattt caaggggaga agtaaaagtt
     2101 ccagtactag ggacaggact taatcaaagt attatagtgg taaatgatga tacatatttt
     2161 aaactaagag ataagggtca acaagtgtat ttttatggtg caaaggtatt tcaagaagaa
     2221 aatagtcaag taatgttcaa caatattgaa aagaatttaa gtttaaaaaa tgggtatatt
     2281 caaaatggat ataaagctca aggtgagagt caatggatga agtttgcata tgtagtgctt
     2341 gtgtttttat tcttagtctt tgcaattgta gctggaagta taatatatat gaaaatatat
     2401 agtgatgcat atgaagataa agagaaatat aagattttgt taaaaatagg tactacagaa
     2461 aaagatataa atagagctat acttaaagaa gtagctattt tttatacttt gccaatgtta
     2521 agtgcaacta tatctagtta ttttgcattg agattagcag gagatttatt gatgaccgat
     2581 ttatttggta tatatatact aagtttagtg atatgtttga taatattcat aatatatgga
     2641 gcagtatctg ttaataagtt taagagtgta gtgtataaaa attagttgat atattaataa
     2701 agagaaagga gattcttgta ataagagtct ccttgttgat taactaaata atttgggtaa
     2761 taaattcata taaaatatgt tatgatatta ataattcata gcatagtgaa atattaggat
     2821 aatggagaat atacaaatgt atagaatttt attagtagag gacgatattg atttatcaaa
     2881 agagattgcg ttagcacttg aaaaatgggg atttaaagta gaattaattg atgattttga
     2941 ggtagtatta gatgaattta tagataaaaa accagatgta gtacttttag atgtaaattt
     3001 accattatat aatggatttt actggtgcga aaaaataaga gctatttcaa atgtaccatt
     3061 aatattttta tcatcaagag attctgatat ggatttaata atgggcataa ataatggagc
     3121 agatgattac attaccaaac cattttctat agaaatattg gttaccaaaa taaatggtat
     3181 aataagaaga gtctataatt atagtgattc taatagtatt ttgtattgtg aagatttgat
     3241 gtttgatgtg gggaaaggga ttataaaaca taagtataag gataaaagta tagagttgac
     3301 taaaaacgaa ataaaaattt taacattatt attaaaaaat aagaataggg ttgtatcaag
     3361 ggaaagtctt atgatgactc tatgggataa tgacgagttt gtgacagaca atgcacttac
     3421 tgtaaatatg aatagattga gaagtaaagt taaagaactg ggttttgatg attttataaa
     3481 aactaagaag gggataggat atataataca atgctagtaa aatatttgaa aggtaggtct
     3541 aagtatattg ctctaccttt agttgtagtt agtataataa atatctactt atttgctata
     3601 gatattttta aaaataaata ttcagagtta a
//
LOCUS       DAEPKC010000177         3494 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.180, whole genome shotgun sequence.
ACCESSION   DAEPKC010000177 DAEPKC010000000
VERSION     DAEPKC010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3494)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3494)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3494
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.180"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     repeat_region   3..560
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=3..31
                     /rpt_unit_seq="atttacattccatatagttaatataaaac"
     gene            complement(1219..3312)
                     /locus_tag="KR294_003647"
     CDS             complement(1219..3312)
                     /locus_tag="KR294_003647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBH0241688.1"
                     /translation="MNKHNFEVILNQLQINIYVTNIHTNEIIFMNKKMKEEYNILDPE
                     GKVCWQVLYPEKNSTCSFCKVLELLKNDKKGVLIKWYEKCNKLNRVFENYDSLITWQD
                     GTVVHMHQSIDIANSTSLNKPIKINEFHEISNNKEEKGVFNFSRDNFDYNSTLLYDAL
                     IRGTDEYIYICNMKTGVFRYSPSQVELFDLPGEIVENPLVYWKKIVHPEDWNRFYKSN
                     TEIGKNQMDYHTVEFRAKNRSGEYIWLRCRGQLMRDEFGEPSIFAGIMTQLGKQNKID
                     SLTQLLNYHEFMSVFEDKISNPMIEKLCIVLLDIDDFKNVNEMYDRDFGDNIIKTLAQ
                     SIQSILPDNAELYKLDGDEMGILVDNVEENEILTLYNQIQNMIIHLQLWRKYGLNITI
                     SAGCVIYPKHGDTVKELYKCASYSLQYAKEHGKNRLVFFSQEILKNKMYSLEMMRDLK
                     ASINDDFRGFSLRFQPQVDTESHKIIGVEVLLRWTNDKCKAISPLEFIPILEENDMIN
                     IVGAWVLRMALRTFRKWIDYYPFFKVSVNVSAVQILEDTFIEDIVKIIDDENFPYQNL
                     VLELTESHTVQNMSILQFKFKALQDLGIYIAMDDFGTGYSSLEVLKFSPIDIVKIDRV
                     FVKDILKSKFDATFIHFIVAICHDVGIKVCLEGVETQEEYDLVKQIKPDYIQGYLFGK
                     PQTATEIFDLLKLDN"
BASE COUNT         1226 a          560 c          334 g         1374 t
ORIGIN      
        1 atatttacat tccatatagt taatataaaa cctgcttaat gcagaattaa gagaggaagt
       61 gttataagat ttacattcca tatagttaat ataaaactgg ttgttcctgc tccggtgttg
      121 gtggaactgg tacatttaca ttccatatag ttaatataaa acgaatatgt atggataatt
      181 ttttacttaa catattagca tttacattcc atatagttaa tataaaacct gctgtaattt
      241 ctgatgaagc ttctccacta ccaccattta cattccatat agttaatata aaacccttct
      301 ttaactctta tcgtatttaa acctcttata acatttacat tccatatagt taatataaaa
      361 ctttttgtgt taagaagaaa aaagaaattt tgataatatt tacattccat atagttaata
      421 taaaacctta aagaaaaaat ggaggaagat taagtgaaaa aattatttac attccatata
      481 gttaatataa aactggattt aaataatcaa aacaactccg gtttaaaaaa catttacatt
      541 ccatatagtt aatataaaac cccaaaataa acttagtatt ttcaacactt acacgtatac
      601 aactctctta aatttgcagt gaacgagcaa tagtgcaatt gataacgctt atcatacact
      661 ctcaacgcct tatatttcaa ctgttacgcc aaattttttc acaaatatcg ctcactgcaa
      721 aattcctata attttattat atcataaata tattactttt gaatattgat accaatttat
      781 accataataa aagcaaaaaa acgtaatcta tctacattag atttaaattc tataacttaa
      841 agttttttac ataatattta tgcttgttta atcaatctaa tatatcattc ttgtatattg
      901 cttttaatag tcttttttct taaataaata tctatctgaa caagcatagt ttaattaaaa
      961 acttttgtat tcccttaaaa ctgtatctac ctcttattat tttatttatg atatattatt
     1021 tttaatctaa aaatagatat ctatttttat tatggttatc cctttttaaa atactttaat
     1081 catatactat tcccaattta acatccattg aaatgctatt ttcttatatt gcaatttata
     1141 attgatatat cttcaatata ataatttaat gtatttttga ttttaaagct tttcagtgat
     1201 attattgata aattagaatt aattatctag ctttaaaagg tcaaagattt ctgttgctgt
     1261 ctgcggtttt ccaaataaat atccttgtat gtaatctggc tttatttgtt taactaaatc
     1321 atactcttct tgtgtttcta caccttctaa acatactttt attcctacat catgacaaat
     1381 tgcaacaata aaatgtataa atgtagcatc aaacttactc tttaatatat ctttaacaaa
     1441 tactctatca attttcacta tatctattgg agaaaatttt aaaacttcta gagacgagta
     1501 tccagtacca aaatcatcca tagcaatata aattcctaaa tcttgtaaag ccttaaattt
     1561 aaactgtaaa atactcatat tttgtactgt atgactttct gtcaattcta aaacaagatt
     1621 ttgataagga aaattttcat catctataat ttttactata tcttcaataa atgtgtcttc
     1681 taatatttga acagctgaaa cgtttacact cactttaaaa aaaggatagt aatcaatcca
     1741 tttcctaaaa gtacgtaatg ccattcgaag cacccaagcc cctacaatat ttatcatatc
     1801 attttcttct aatattggaa taaattccaa aggagaaatt gctttgcatt tgtcattagt
     1861 ccaccttaaa agaacttcta cacctattat tttatgactt tctgtatcta cttgtggctg
     1921 gaatcgaaga ctaaaccccc taaaatcatc attaattgat gcctttaaat cccgcatcat
     1981 ttctaatgaa tacattttat tttttaatat ttcttgggag aaaaaaacaa gcctgttttt
     2041 accatgctct ttcgcatatt gtaaagagta actagcacac ttataaagtt cttttactgt
     2101 atctccatgt tttggatata ttacacaacc agcagaaatt gttatattta atccatattt
     2161 tctccatagt tgaaggtgta taatcatatt ctgtatttga ttatatagag ttagaatttc
     2221 attttcttca acattatcaa caagaatgcc catttcgtcc ccatcaagtt tataaagttc
     2281 agcattatct ggtaaaatag attgtataga ctgtgctagt gtttttatta tattatctcc
     2341 aaaatcccta tcatacatct cattaacatt tttaaaatcg tcaatatcta ataatactat
     2401 gcataatttt tcaatcatag gatttgaaat tttatcttca aatacactca taaattcatg
     2461 ataattcagt aactgtgtca atgaatcaat cttattttgt ttacctaatt gcgtcattat
     2521 tcctgcaaaa atacttggtt ctccaaattc atcacgcatt agttgacctc tacatcttaa
     2581 ccatatatat tctccactac gatttttagc cctaaattcc actgtatgat aatccatctg
     2641 gtttttacct atttcagtgt ttgacttata aaaacgattc cagtcttctg gatgtacaat
     2701 ttttttccag taaacaagcg gattttcaac aatttctcct ggtaagtcaa ataattcaac
     2761 ttgtgatggt gaatatcgaa atacgcctgt tttcatattg caaatgtata tatattcatc
     2821 tgtacctcta atcaaagcat cataaagcaa tgtagaatta taatcaaaat tgtctcttga
     2881 aaaattaaaa actccttttt cttctttatt atttgatatt tcatgaaatt cattaatctt
     2941 aattggttta tttaagcttg ttgagtttgc aatatctatt gattgatgca tatgaacaac
     3001 tgtgccatct tgccatgtaa ttaaactatc ataattttca aaaacacgat ttaacttatt
     3061 acatttttca taccacttta ttaatactcc ttttttatca ttctttaata attctaaaac
     3121 tttacaaaaa ctacaagtag aatttttttc aggatataat acttgccaac aaacttttcc
     3181 ttctggatct aaaatattat attcttcttt catttttttg ttcataaaaa taatttcatt
     3241 agtatgaata tttgtaacat atatattaat ctgtagttga tttaatataa cttcaaaatt
     3301 atgtttgttc atatacttat ctcctccata gttactgctc tttataacaa cattgttaaa
     3361 attattcttt ttagaagatt tacttataac ttatacatat acactaaata ccttaattta
     3421 attagaaagt ttattacttc atattttaaa ttataattga taaaaaaaaa tacagcaata
     3481 tagtattacc aatt
//
LOCUS       DAEPKC010000178         3395 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.181, whole genome shotgun sequence.
ACCESSION   DAEPKC010000178 DAEPKC010000000
VERSION     DAEPKC010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3395)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3395)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3395
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.181"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(288..896)
                     /locus_tag="KR294_003648"
     CDS             complement(288..896)
                     /locus_tag="KR294_003648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HBH0241689.1"
                     /translation="MEKDFFRKNGIDLAKSILGKYLIRKYENKVIVTKIIETEAYMGV
                     NDKGAHVYGNKKTDRTKPLYLDGGHIYVYLIYGMYNCLNLSANIENVPECVLIRGVEP
                     ITSLDEISMNRYNKAYTELSKYQVKNITNGPGKLCKALKIDRSLNSKSIMGEELYISD
                     FYYDDKGKKVFSKDELDIKTSKRINIDYAEEAKDFLWRFYIE"
     gene            complement(1005..>3395)
                     /locus_tag="KR294_003649"
     CDS             complement(1005..>3395)
                     /locus_tag="KR294_003649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing sensor histidine kinase"
                     /protein_id="HBH0241690.1"
                     /translation="SPILIFYSAFVILDYFIRNIFSDINWNMIIILINVCISMFNLLY
                     LLNKLDSNIEHYKLIKDLTYFVFFTTIICFVAISKINIVDSDRLIGVIYLLLCNHTYY
                     VYVYSLNNRVVYPYYELDSINKKLSKKSEQLGKINLAIEKDMIIQRTLKNYIDQRKEL
                     LRQALDTIPNVWIVTDYDFNISYTNNKFKDEFSKDMNNYYKILTFIKEDEKVAEKLKK
                     FDNDISIIDKLVELNDKIYLLSLSNNKDESNYLISLNDITNEIKIDEEIRNINKDYEN
                     IILNIPSPILVRSAEGGIKKNKVISINKKYEKSFKCVSSDLVDMTLEQYFETFNIDFF
                     DNREFKRLNLTQEKKAEIVSYNDTANCIVNFVMSDSEGEEHVEEVRVGDYWSDNKLFK
                     LLTFRDITKEINILRTVNEQKIIYEKLLDVIPEAIFLEDLSTSRVLYTNRAFRELFGI
                     SSDVLGVTTQKYRNILVKKYINNLNIGEREKSIHIVNENNHIKEVKMISRTLYFGQKR
                     SRVRIIKDLSVQRESERLKKALIKQRQYDQMKMEFYANISHELKTPLNNIYSSVQLIE
                     NLYKKGKIIDFQDILKEHIKITKQNMFRLLRLIDNIINISQVKSDIYKIKAVNFDIID
                     ITERIVTSISSYAKSKGIDLIFDTDEETVMVGLDPESIERIILNILSNAIKFTLEGGE
                     ILVGIYKKDETVEIIIKDTGVGIDKEKLNDIFNRFKQIENSGISNEFGSGIGLCLTKS
                     LIEIQNGKIYIDSKVGEGTNVKVIFPIKEVVEEVYDNSNYNDNIEKFEIEFFDIYK"
BASE COUNT         1127 a          534 c          258 g         1476 t
ORIGIN      
        1 tttgtcaaaa tttcttcatt ctttaataat taatttatta cttataaaat aaactaatta
       61 tctatacaaa ttttataatt tttaataaaa tacacaaaaa aattaatttt tatagctcat
      121 ttcgccaaaa tatatctttc tttatatcat gaaaataatt ataaatttat taaatatgtt
      181 tgtaattcta taaagttatt tttatcaaac taaaaattct ataaaaaaat aagatacata
      241 cctataaaat accttcctat agatacatat cttacctata taaaaactta ttctatataa
      301 aaacgccata aaaaatcttt tgcttcttct gcataatcta tatttatacg tttactagtt
      361 tttatatcta actcatcttt actaaatact ttttttcctt tatcatcata ataaaaatca
      421 cttatatata attcttcacc cattatactc ttactattta gacttctatc tatttttaaa
      481 gctttgcaaa gttttcctgg tccgttagta atatttttta cttgatattt actcaactca
      541 gtgtaagctt tgttgtatct attcatagat atctcatcta aagaagttat aggctctacc
      601 cctcttatta atacacactc tggcacattt tctatatttg cagataaatt caagcaatta
      661 tacataccat aaattaaata aacatatata tgtccaccat ctaaatataa tggcttagtt
      721 ctatctgtct ttttattgcc atatacatgt gctcctttat catttacacc catgtatgct
      781 tctgtctcta tgattttggt aacaattact ttattttcat atttccttat tagatattta
      841 cctaatattg atttggctaa atcaattcca ttttttctaa aaaaatcctt ttccaaaatt
      901 tcacctcata aaatttattt aaaacgcatc aaatacaact aaagtaataa ataaaattaa
      961 ctcttattaa tgtgatatat ataaacaata aatttagaca tttattattt atatatatca
     1021 aaaaattcta tctcaaactt ttcaatatta tcattgtaat ttgaattatc atatacttct
     1081 tcaacaacct ctttaattgg gaatataact tttacattag ttccttctcc taccttacta
     1141 tctatgtaaa tcttcccatt ttgaatttca atcaatgatt ttgtaaggca taaacctata
     1201 ccacttccaa attcatttga tataccactg ttttcaattt gtttaaatcg attaaatata
     1261 tcatttaatt tttctttgtc tatgcccact ccagtatctt ttataattat ctctactgtt
     1321 tcgtcttttt tatatatacc tacaaggatt tctcctcctt ctaaagtaaa ttttatagca
     1381 tttgataata tatttagtat tattctttct atcgattctg ggtcaagccc taccataaca
     1441 gtttcttcat ctgtatcaaa aattaaatct attcctttag acttagcata actactaata
     1501 gatgtaacta ttctttctgt tatgtcaata atatcaaaat taactgcttt aatcttatat
     1561 atgtctgact taacttgaga aatatttatt atattatcta ttaatctcaa taatctaaac
     1621 atattttgtt tagttatttt tatatgttct tttagtatat cctgaaaatc aattattttt
     1681 ccttttttat aaaggttttc aataagttga actgaactat atatattatt taaaggtgtc
     1741 ttaagttcat gagatatatt agcataaaac tccatcttca tttggtcata ctgtctttgt
     1801 tttattaatg cttttttaag tctttcagac tctctttgca cacttaaatc tttaataatt
     1861 ctcactctac ttcttttctg tccaaagtat aatgttcttg atatcatttt tacttcttta
     1921 atgtgattat tttcatttac tatatggata ctcttctctc tttctcctat atttaaattg
     1981 tttatgtatt tttttactaa tatatttcta tatttttgtg ttgtaactcc taatacatca
     2041 ctagaaattc cgaacaactc tctaaaggct ctatttgtat atagtactct tgatgtactt
     2101 aaatcctcaa gaaaaatagc ctctggtata acatccagta atttttcata tattattttt
     2161 tgttcattta ctgttctaag aatatttatc tctttagtta tatctctaaa tgtaagcaat
     2221 ttaaagagtt tattatctga ccaatagtct ccaactctaa cttcttcaac atgctcttca
     2281 ccttctgagt cagacatcac aaaattaact atacagtttg ctgtgtcatt gtaacttact
     2341 atttcagctt tcttttcttg tgttagattt aatcttttaa attccctatt gtcaaagaaa
     2401 tctatgttaa aagtttcaaa atattgttct aatgtcatat cgactaaatc acttgaaaca
     2461 catttaaaac tcttttcata ttttttattt atacttatta ccttattctt ctttatgcca
     2521 ccttcagcac ttcttacaag tataggagat ggaatattta gtataatgtt ttcatagtct
     2581 ttatttatat ttcttatttc ttcatctatt ttgatttcat ttgtaatatc atttaaactt
     2641 attaagtaat tgctttcatc tttattatta cttaaactta acaaataaat tttatcattt
     2701 aactctacca gtttatcaat tatacttata tcgttatcaa atttcttcaa tttttcagca
     2761 actttttcat cttcctttat aaaagttaat attttataat aattattcat atcctttgaa
     2821 aattcatctt taaatttatt atttgtgtaa cttatattaa aatcatagtc tgttactatc
     2881 catacatttg gtattgtatc cagagcttgt ctaagtaatt cttttctctg gtctatgtag
     2941 ttttttaatg ttctttgtat aatcatatcc ttttctattg ctaaatttat ctttcctaat
     3001 tgctctgact ttttacttaa ttttttattg attgaatcaa gttcataata tggatacact
     3061 actctattat taagactgta tacatataca taataagtat ggttacataa tagtaaatat
     3121 attactccta ttaatctatc tgaatctact atattaatct tagaaattgc tacaaaacat
     3181 ataatagttg taaaaaaaac aaaatatgtt aaatctttta ttaacttata gtgctcaatg
     3241 ttactatcaa gtttattcaa caaatatagt aaattaaaca tagatataca aacattaatt
     3301 aatataataa tcatattcca gttaatatca ctaaaaatat ttcttataaa gtaatctaat
     3361 atcacaaaag cactataaaa aattagtatt gggct
//
LOCUS       DAEPKC010000179         3376 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.182, whole genome shotgun sequence.
ACCESSION   DAEPKC010000179 DAEPKC010000000
VERSION     DAEPKC010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3376)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3376)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3376
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.182"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(93..458)
                     /locus_tag="KR294_003650"
                     /pseudo
     CDS             complement(93..458)
                     /locus_tag="KR294_003650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423610.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
     gene            complement(479..1558)
                     /locus_tag="KR294_003651"
     CDS             complement(479..1558)
                     /locus_tag="KR294_003651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF917 domain-containing protein"
                     /protein_id="HBH0241691.1"
                     /translation="MRFLTEESVDKIAVGAAVLGTGGGGDPYVGKLVAKQAIKKYGPV
                     KVISLDELDDDALVVPVSGMGSPVITIEKLLSEVELTTPLEIMEKLLNRKVDVIIPIE
                     IGGINSLMPIAVAAKKGLPILDADSMGRAFPEAQMVTFYLEGYEASPAVMSDEKGNSA
                     ILYPVDGIWSERLARTLTVEMGGSSSISDYNLSGAQVKKAAIGNTLTIAETIGGFLLE
                     NKSDSKGAVENILKELRGYKLFEGKVIDIKRELKGGFTRGHAFFAGINEYDGEYSILF
                     QNENLIAKKGDTPLCITPDLIAVLDLETGFPITTERIKYGSRVMVVAFPCNEKWRTEK
                     GIETVGPGYFGYDVEYKTVEELQGK"
     gene            complement(1612..2901)
                     /locus_tag="KR294_003652"
     CDS             complement(1612..2901)
                     /locus_tag="KR294_003652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosine permease"
                     /protein_id="HBH0241692.1"
                     /translation="MEEEKINYALEQIPENQKRGWVAMFSVLVAIGVDLSSVILGAEL
                     AQSMPMKQAILSVIVGSFFSAILYTTCSLVGSSTSLSTSMITKYVFGEAGAKIFSLVI
                     GVSLLGWFGVQVGFFAQNAQIIIKDIFNLDVSMQILSLIGGLLMMSTAIYGYKAMEKL
                     SVYSVPFLLVLMMLTIFLAFRANGISVDDNMKSTMTFAGGVSLSMSIIIVGAIVSPDI
                     SRWAKSRRDCALSSFLGIQFGNAFMIIVSIVLVKCMGTSDIMRIFITLGIAIPGIIVL
                     TLAQWTTNTSNVYSASLSIALVLKKAPEKVLTIVLGIIATLLAVFGIYEGFIGFLNLL
                     GIVIAPVGGVYTAEYYIVKQELKGFDKGVLYKPIVKRSIVSWIIGILITYLSTYGFIT
                     LTTIAPLDGFIAGFVVQSIIGKVLCSTKNKQEIDKAV"
     misc_binding    complement(3064..3275)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
BASE COUNT         1111 a          678 c          372 g         1215 t
ORIGIN      
        1 tatcctatct ctacatatag gtttccctat atgctgacta ttttagctac taactcatga
       61 ctaaagtcac gagtgtgcgt agctattttt taatcaaact catatccacc agataccaat
      121 attgaatcta attctatttt ttctcttaag tcttctggcc aatctataaa tggaagaatg
      181 gcagtagtgg ctggctttcc tattcttatc atagccacat tattaagtct ttttctttct
      241 acaatagcat ttgtacaatg agttgtacca agcatagcat attttattaa tgaatggtca
      301 atcttacttt catctataac tttttttaag gcattgtaaa caccagtttc aacatctttt
      361 gtagttgcca ccttaactga atgaattact tttaattccc catccagtat acaagcatct
      421 gtatttgttc ctccaacgtc aattcctaca cgatacatca aaatttcctc ctaaactttt
      481 attttccttg taattcttct actgttttat attccacatc atatccaaag tatccaggtc
      541 caactgtctc aattcctttt tctgttctcc atttttcatt acaaggaaaa gctactacca
      601 taacacgaga gccatatttt attctctctg tagttattgg aaatccagtt tctaaatcta
      661 atactgctat taaatctggt gtaatacaaa gtggtgtatc accttttttg gcaattaaat
      721 tctcattttg gaataatata gaatactctc catcatactc attaatccca gcaaaaaagg
      781 catgtcctct agtaaatcca cctttcaact ctctcttaat atcaattact tttccttcaa
      841 ataacttgta tccacgcaat tcttttagta tattctcaac agcacctttt gaatcagatt
      901 tattttcaag taaaaaccct cctatagttt cagctattgt aagagtatta cctatagcag
      961 cttttttaac ttgagctcca cttaaattat agtcactaat agaagaactt cctcccattt
     1021 ctacagttaa agttctagct aatctttctg accaaattcc atccacagga taaaggatgg
     1081 cagaattacc tttttcatca gacattacgg caggagatgc ctcatatcct tcaagataaa
     1141 aagttaccat ttgagcttca gggaaagctc tacccataga atctgcatct aagataggaa
     1201 gtcctttttt agcagcaact gctataggca taagtgagtt tatccctcct atttctatag
     1261 gaattataac atccactttt ctatttaata atttctccat tatttctaaa ggggtagtta
     1321 actcaacttc tgaaagtaat ttttctattg taattacagg agaacccata ccagatactg
     1381 gaactaccaa agcatcatca tcaagttcat ctaaacttat tacttttaca ggaccatact
     1441 ttttaatggc ttgttttgca accaatttac ctacatatgg gtcacctcca cctccagttc
     1501 caagcactgc tgcaccaact gctattttat ctacactttc ttctgttaaa aatctcatgt
     1561 tactttctcc tcatatttct aatttatttt atactttata aacaaatttc tttatactgc
     1621 tttgtctatt tcttgcttat tttttgttga acaaagcact tttccaataa tagattgtac
     1681 tacaaaccct gctataaaac catctaaagg tgctatagta gtaagagtta taaatccata
     1741 tgttgaaagg taagttatta atataccaat tatccaagac actattgaac gtttaactat
     1801 tggtttatat aatactcctt tatcaaagcc tttaagttct tgctttacta tgtaatattc
     1861 tgctgtatat acaccaccaa caggtgcaat tacaattcca agtaaattta aaaatcctat
     1921 aaaaccttca tatattccaa atacagccaa taatgttgct ataataccaa ggactatagt
     1981 taatactttc tcaggagcct tcttaagtac aagagctata cttaatgatg ctgaatatac
     2041 attacttgta tttgtagtcc attgtgctaa tgtaagtact attatacctg gtatagcaat
     2101 tcctaatgta ataaaaattc tcataatatc tgaagttccc atacatttta ctaatactat
     2161 cgaaactatt atcataaaag catttccaaa ttgtattccc aaaaagcttg aaagagcaca
     2221 gtctcttcta cttttagccc aacgacttat atcaggagat acaattgcac caactattat
     2281 tatactcatt gacagagaaa ctccacctgc aaatgtcata gtagatttca tattatcatc
     2341 aactgaaatt ccatttgctc taaaagctaa gaatatagtt agcatcataa gaactaataa
     2401 aaatggtact gaatacacac tcaacttctc cattgcctta tatccataaa ttgcagtact
     2461 catcatcaag agaccaccta ttaggcttaa aatctgcata cttacatcta aattaaatat
     2521 atcttttatt attatctgtg cattttgagc aaagaaacct acttgaactc caaaccaacc
     2581 taatagagaa acccctataa ctagagaaaa tatttttgct ccagcttctc caaatacata
     2641 ctttgttatc atagatgtag ataaacttgt agatgagcca accaaagagc atgtagtata
     2701 caaaattgca gaaaaaaatg aaccaacaat tactgacaat attgcttgtt tcattggcat
     2761 actctgtgcc aactcagcgc ctaaaataac agatgataaa tccacaccta ttgctactaa
     2821 aactgaaaac atagctaccc aaccacgttt ttgattctct ggaatctgtt ccagagcata
     2881 gttaattttt tcttcttcca ttttcatccc tccatttaaa tcgtaaaact actgacctta
     2941 gcatatttta caattttcta atttataaat ttattaacta tcatattttt ataattttca
     3001 tttaatatat agttttaaat tttctgaaat aagtttataa taaaaaacgc ctcttggaaa
     3061 aatccaagag acgaatataa atccgtgtta ccactcttat tagtaaaaat taattttact
     3121 cactcatttt cttaaggcga attaaaccac tattctaaca taattacaat agtattctcc
     3181 aaagtccttt tcacataaat tccaatatta gttctcagcc aaatctaact ctctgtaaaa
     3241 ttcctttatg ctactttctt cttctacgaa tatataatat tgatttgtag ttaatttatg
     3301 atttatatca taatatatat gcaatatttt gtcaacttaa aaagtcaatt acttgcattt
     3361 tttagtttta tatgta
//
LOCUS       DAEPKC010000180         3281 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.183, whole genome shotgun sequence.
ACCESSION   DAEPKC010000180 DAEPKC010000000
VERSION     DAEPKC010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3281)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3281)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3281
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.183"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..1424
                     /locus_tag="KR294_003653"
     CDS             <1..1424
                     /locus_tag="KR294_003653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="cell wall-binding protein Cwp28"
                     /protein_id="HBH0241693.1"
                     /translation="ISFVFANIQLVDAISSVEKIQGKNKYEIAGKIADKNAYKTAYKT
                     AYKTAILINTSNSIADGLSASGLAGALNAPILLTEKNTIPTETSARLKNVSKVYIIGG
                     TYSISTSVENSLKSKKMKVVRIKGNDRIKTSYNVAKEINSIKKVNTVMLTNAYKGEAD
                     AISIASVAARDKAPIILTNGQSIPFSTSGLKSYVIGGTASMSTTLVNNTKSTRLGGST
                     RFETNKAIINKFYKDAREFYIAGAYELTNALVGSSLSKHGPMVLVNDGSNKSILKNAK
                     KITSIGYIDSNIVQQCLNITNGIGDINTGVVKNVKPTTKTIKDGMYKVGKDISAGEYL
                     ITSNSGSYASYYEVTSDSTGNADSILSNDIFSGTRYITLKNGQYIKIEDSTMTLAKYA
                     KAQKAKNGKFGNGMYKIGLEIPAGEYIIMSNSSDAYYEVRNDSLGNAEGIVTNDTFSG
                     RRYITVEEDQYLILNDCYLIENE"
     gene            1672..3108
                     /gene="miaB"
                     /locus_tag="KR294_003654"
     CDS             1672..3108
                     /gene="miaB"
                     /locus_tag="KR294_003654"
                     /EC_number="2.8.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (N6-isopentenyl
                     adenosine(37)-C2)-methylthiotransferase MiaB"
                     /protein_id="HBH0241694.1"
                     /translation="MSKRKQVTIPIEKIQEQDKYIEQIHRQNEEYFNRTGKRKLVFTQ
                     TFGCQMNEHDSEKLCSMLEEMGYQMSMMVEESDLIIYNTCAVRENAELKVYGNLGQLK
                     HLKGKNPDMKIAVCGCMMQQPHVVEELRKKYKHVDLIFGTHNLYKFPQLLTESINSDK
                     MLVDVWDVDGEVIEGLRSNRKFELKAFVNIMYGCNNFCTYCIVPYTRGRERSRTPEDI
                     INEIKELVANGTKEITLLGQNVDSYGKTLENPVSFSELLRKVNDIEGIERVRFMTSHP
                     KDISDEVIYAIRDCDKVCEFLHLPIQCGSSSLLKKMNRHYTKEYYLEIIEKAKKEVPG
                     IAFSTDLMIGFPGETEEDLLDTLDVVEKVRYDSAFTFIYSKRQGTPAAKMENQIPEDI
                     KHDRFNRVLEAVNRISAEINDGYKDRIVEVLVEGRSKNNENKFAGRTRQNKLVNFEGG
                     NDDLIGKLVMVKITEPRTFSLNGILVNN"
BASE COUNT         1371 a          336 c          570 g         1004 t
ORIGIN      
        1 gtatttcttt tgtatttgca aatattcaat tagtagatgc aatatcatct gtagaaaaaa
       61 tacaaggaaa aaataagtat gaaatagcag gtaaaatagc agataaaaat gcatataaaa
      121 ctgcatataa aactgcatat aaaactgcta tattaattaa tactagtaac tctattgcag
      181 atggattaag tgcaagtgga ctagcaggag ctttaaatgc ccctatacta ttaactgaaa
      241 aaaatactat accaactgag acatctgcaa gattaaaaaa tgtatcaaaa gtttatataa
      301 ttggaggaac atattctatt agtacatctg tcgaaaattc attaaaatct aagaaaatga
      361 aagttgtaag aattaaggga aatgacagaa taaaaacaag ttataatgtt gcaaaagaaa
      421 taaattcaat aaaaaaagtc aatactgtta tgctaaccaa tgcatataaa ggagaagcag
      481 atgctataag tattgcatct gtagcagcaa gagataaagc accaataatt cttactaatg
      541 gacaaagtat acctttttca actagtggtt taaagtctta tgtaatagga ggaacagctt
      601 caatgagtac cactttagta aacaatacta aatctactag actagggggg agtactcgtt
      661 ttgaaactaa taaagcaata ataaataagt tttataagga tgctagagag ttttatatag
      721 ctggagctta tgaattaaca aatgcacttg taggatcttc tttatcaaaa catggtccaa
      781 tggttttagt taacgatggt agcaataaaa gcattttaaa aaatgctaag aagataactt
      841 ctataggata tatagattca aatatagtac aacagtgttt aaatataaca aatggaattg
      901 gagatattaa tactggggtt gtaaaaaatg ttaaacctac tacaaagact ataaaagatg
      961 gaatgtataa ggttggaaaa gatatctcag caggtgaata cttaataact tcaaactcag
     1021 gaagttatgc ttcttattat gaagttacaa gtgatagtac aggtaatgct gatagtatac
     1081 tttcaaatga tatttttagt gggactagat atatcacctt aaagaatggt caatatatta
     1141 aaattgagga ttcaacaatg acattagcaa agtatgctaa agcccagaag gccaagaatg
     1201 gtaagtttgg aaatggtatg tataaaattg gattagaaat tcctgctgga gaatatatta
     1261 taatgtcaaa ttcttctgat gcatattatg aagttagaaa tgatagctta ggtaatgcag
     1321 agggaatagt tactaatgat actttttcag gaagaagata tataacggtt gaggaagatc
     1381 aatatttaat attaaatgat tgttatttaa ttgaaaatga atagatgtaa ttgtatttaa
     1441 tagtaaatca tatattttat ttaaggaaag gtgttttaag ttttaattta aaacatcttt
     1501 ttattattat aataattata tgattttata ttttagaaat atagtatata taaatcatta
     1561 gatttactat taaaacacaa ctagaaaaat aataatatct ttaaaagatt tttcttattt
     1621 gatataatta aggttatgtg taatataaga aattaactag gaggaataga cgtgagcaaa
     1681 agaaaacaag taacaatacc tatagagaaa atacaagaac aagataaata tatagaacaa
     1741 atacacagac aaaatgaaga atacttcaac agaactggaa agagaaaact cgtgtttact
     1801 caaaccttcg ggtgtcaaat gaatgaacat gattcagaaa aattatgttc aatgttagaa
     1861 gagatgggat accaaatgtc aatgatggtt gaagaaagtg atttaataat atataacacc
     1921 tgtgcagtta gagaaaatgc agagctaaaa gtgtatggta acttaggaca attaaaacat
     1981 ctaaaaggaa aaaatccaga tatgaaaata gctgtatgtg gatgtatgat gcaacaacca
     2041 catgttgtag aggaattaag aaaaaaatat aaacatgtag accttatatt tggaacacat
     2101 aatctatata aatttccgca attacttaca gaatcaataa attctgacaa aatgttagtg
     2161 gatgtatggg atgtggatgg agaagtaata gaaggtctta gaagtaatag aaaatttgaa
     2221 ttaaaagcat ttgtaaatat aatgtatgga tgcaataatt tctgcacata ttgtatagtc
     2281 ccatacacaa gaggaagaga aagaagtaga actcctgaag atataattaa cgagataaaa
     2341 gagcttgttg caaatggaac gaaagaaatc actttacttg gacaaaatgt agattcttat
     2401 ggtaagacac ttgaaaatcc agtttcattc tcagaacttt taagaaaagt gaatgatata
     2461 gaaggaattg aaagggttcg atttatgaca tctcatccaa aagatatatc tgatgaagta
     2521 atatacgcaa ttagagattg tgataaggtg tgtgagtttt tacatctacc aatacaatgt
     2581 ggaagcagta gccttttgaa aaaaatgaat agacattata caaaggaata ttatttagaa
     2641 ataatagaaa aagctaaaaa ggaagttcca ggtattgctt tttctacaga cttaatgatt
     2701 ggtttcccag gagaaacaga agaagattta ttggacactt tagatgtggt tgaaaaagtt
     2761 agatatgatt cagcttttac atttatttat tctaaaagac agggaactcc tgctgctaaa
     2821 atggaaaatc aaataccaga agatataaag catgatagat ttaatagggt gttagaagct
     2881 gtaaatagga tttctgcaga aataaatgat ggatataaag atagaatagt tgaagttcta
     2941 gttgaaggaa gaagtaaaaa taatgaaaat aagtttgctg gtagaactag acaaaataaa
     3001 ctcgtaaatt tcgaaggtgg aaatgatgat ttaattggta aattagttat ggtaaaaatt
     3061 actgaaccta gaactttttc attaaatggg atattagtaa ataattaata ttgtacaaaa
     3121 taataaaatt atgtaaacta atcaaaatag atgtactata gaacaaatta tattaaaaat
     3181 ttttatttta agcgaatttg tcatatgtta tgctaatgta agtttttgct attaataaaa
     3241 ataaatttga tataagatat aatttcattg tacatctatt t
//
LOCUS       DAEPKC010000181         3226 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.184, whole genome shotgun sequence.
ACCESSION   DAEPKC010000181 DAEPKC010000000
VERSION     DAEPKC010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3226)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3226)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3226
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.184"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            325..2460
                     /gene="rnr"
                     /locus_tag="KR294_003655"
     CDS             325..2460
                     /gene="rnr"
                     /locus_tag="KR294_003655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HBH0241695.1"
                     /translation="MIPGLKESLLGLINESAYNPLKKEELAEIFDIHSSEMPMFYNFL
                     NELEEDGYICFTKKGKIVSPNQMGYFVGKFVSHKKGFGFVESDVEYTQDLFISSDNIN
                     GAMHNDRVMAEIVVPATEEKRAEGRIVKVIKREITRIVGTFQSSKTFGFVTPDNKKFT
                     KDIYIPKKHFSGAVDNDKVVCEITVWPQEDRKPEGKIIEILGQKGERGVEIDSIIREH
                     GLPEEFPKKVLQEAEAVAVEIPQEEIKRRRDLRDLNIFTIDGDDAKDLDDAISIEVLP
                     NGNFKLGVHIADVTHYVREKNKLDKEALKRATSVYLVDKVIPMLPKTLSNGVCSLNPF
                     EDKLTLSIFMEIDHKGNVVKHEICESVINSKARMTYTEVSDILEKDDEKLKKTFEHVV
                     EDFKNAEILARILMSRREKRGAIDFNFPEAKIILNGKGEVVDIKPYERRISNKIIEEF
                     MLISNETIAEHFYWMGIPFVYRIHETPSLEKMEELSKFISTFGYIIKGDKEEVHPKAL
                     QGIIEKIKGKKEEGAISTIMLRSLKQAKYSPECSGHFGLAAKFYCHFTSPIRRYPDLQ
                     IHRIIKESLNNKISGKRQEQLTTIVDYASVQSSEKERKAELAERDVHDFYKALYMKDK
                     VGQEFEGVVSSVTSFGIFVELDNTIEGLIRLANMNDDYYIYDESSYSVLGERTKKSYK
                     IGDLVKIKVESVNVDFKEIDFEIVEKIEE"
BASE COUNT         1428 a          289 c          572 g          937 t
ORIGIN      
        1 atagtaatac ttatatgaga tgaatatttt accaatccta tttgatggtg tataattagg
       61 tgataaagag taatttaagc aattatgata aagaataact taagtaatta taatgatatt
      121 tacaaataat ttataaaaca tcataatttg tttgaagtta gtatgacaaa gattacatta
      181 aatcaaaaat ataaataagt aattttaact tataataata agaaaatata gaaaattatg
      241 tgataagtaa aaaatgtttt gtctgaagaa atataaaaga caatataaat aataatataa
      301 tgaaaagtaa aacaggaggg aaaaatgata ccaggactta aagaaagttt gctaggatta
      361 ataaatgaaa gtgcatataa tcctctaaaa aaagaagaat tagcagaaat atttgatata
      421 cattcatcag aaatgccaat gttttataat tttttaaatg aattagaaga agatggttat
      481 atctgcttta ctaaaaaagg aaaaatagta tctcccaatc aaatgggata ctttgttgga
      541 aaatttgtat cacacaaaaa gggttttgga tttgtagaat ctgatgttga atatacacag
      601 gatttattta tctcaagtga caatataaat ggtgctatgc ataatgatag agttatggca
      661 gaaatagtag tacctgcaac tgaagaaaag agagcagaag gaagaatagt aaaagtaata
      721 aagagagaaa taactagaat agtaggtacc ttccaatcaa gtaaaacttt tggatttgta
      781 acaccagaca acaagaaatt tactaaagat atatatatac ctaaaaaaca ttttagtgga
      841 gcagtagata atgataaggt agtatgtgaa attacagtat ggccacaaga ggatagaaaa
      901 ccagaaggca aaattataga gatactaggt caaaaaggtg aaagaggcgt agaaatagat
      961 tctataataa gagaacatgg tcttccagaa gaatttccaa agaaagtatt gcaagaagca
     1021 gaagctgtag ctgttgagat tcctcaagaa gagataaaaa gaagaagaga tttaagagat
     1081 ttaaacatat ttactataga tggagatgac gcaaaagact tagatgatgc catatcaata
     1141 gaagtattac ctaatggaaa cttcaaacta ggagttcaca tagctgatgt tacacattat
     1201 gtaagagaga aaaataaact tgacaaggaa gccttaaaaa gagctacatc agtttattta
     1261 gtagataaag taattccaat gttgccaaaa actctttcaa atggagtatg tagcttaaat
     1321 ccatttgaag ataagctaac tctttctata tttatggaaa tagaccataa aggaaatgtg
     1381 gttaaacatg aaatatgtga atctgtaata aattcaaaag ctagaatgac ttatacagaa
     1441 gtatctgata tattagaaaa ggatgatgaa aaacttaaaa agacttttga acatgttgtt
     1501 gaagatttta aaaatgctga aattttagct aggattctta tgtcaagaag ggaaaaaaga
     1561 ggagctatag acttcaattt cccagaggca aagataattc taaatggaaa aggcgaagtt
     1621 gtagatataa agccatatga aagaagaata tctaataaga taatagaaga atttatgctt
     1681 ataagtaatg agacaattgc cgaacatttt tactggatgg gaataccgtt tgtgtataga
     1741 atacatgaga caccatcttt ggaaaaaatg gaagaattga gtaagtttat atctacattt
     1801 ggatatataa taaaaggtga taaagaggaa gtacatccaa aagcattaca aggtataata
     1861 gagaaaataa agggcaaaaa agaagaagga gctatcagta ctataatgct tcgttcttta
     1921 aaacaagcta agtactcacc agaatgtagt ggacattttg gattagcagc taaattctac
     1981 tgtcacttta cttcaccaat aagaagatat cctgaccttc aaattcatag aataataaaa
     2041 gaatctttaa ataataaaat aagtggaaaa agacaagaac agcttactac tatagtggat
     2101 tatgcatctg ttcaatcatc cgagaaagaa agaaaggcag agttagctga aagagatgta
     2161 catgatttct ataaggctct ttatatgaag gataaagttg gtcaagaatt tgagggtgtt
     2221 gtatctagcg taacttcatt tggaatattt gttgagttag ataataccat agaagggttg
     2281 ataagacttg caaatatgaa tgatgattac tatatttatg atgagagttc ttatagtgtt
     2341 ttaggagaaa gaactaagaa gtcatataag ataggtgacc ttgttaagat aaaggttgaa
     2401 agtgttaatg tagattttaa agaaattgac tttgagatag ttgaaaaaat agaggagtag
     2461 ataaaacagc taaaataaga gataacaagt tgtagtattt atgatatgta taaatatata
     2521 gtgcacaata ctctataaaa taaatgataa aaataggtaa ttgagaaata tctaatggaa
     2581 atagttaact gaaagataaa taattaagaa atatttaatg aaagtagcta attgaaaaat
     2641 aagtaattga gaaatgttta atagaaagag ctaactgaaa gataagtaat taagaaacat
     2701 ttaatagaaa aagccaactg aaaaataaat aattaagaaa tgtttaatag aagtggctaa
     2761 ttgaaaaata agtaattaag aaatgcttaa tagaagtggc taattgaaaa ataagtaatt
     2821 aagaaatgct taatagaagt ggctaattga aaaataagta attgagaaat gcttaataga
     2881 agtggctaat tgaaaaataa gtaattaaga aatgcttaat agaagtggct aattgaaaaa
     2941 taaataatta agaaatgttt aatagaagtg actaattgaa aaataagtaa ttaagaaatg
     3001 cttaatagaa gtggctaatt gaaaaataag taattgagaa acatttaata gaaaaagcta
     3061 gctgaaagat aagtaattaa gaaatattta atgtaaacag ataatttaaa aatacctaat
     3121 taagaataga tattaaaaaa tataatttca atataaaaat aagtgtatca tttaaaattt
     3181 aagatacact tattttttat ttaagataac ttttcttttt tagaat
//
LOCUS       DAEPKC010000182         3211 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.185, whole genome shotgun sequence.
ACCESSION   DAEPKC010000182 DAEPKC010000000
VERSION     DAEPKC010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3211)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3211)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3211
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.185"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(<1..660)
                     /locus_tag="KR294_003656"
     CDS             complement(<1..660)
                     /locus_tag="KR294_003656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HBH0241696.1"
                     /translation="MKYKLFIDFEFNILDDNKNKPKEYNGAELISIGGVLVDNEFNTI
                     DNYYSLVKPKYNKILSNKCKNLTKLNQLDINNAPNLLYVMDDFYKWFCKFDDVTIYNW
                     GDFDITGLLTSFRVYKYTGKCLELFNMMIDIQPFISQHITYNNRILSKQISLLNMKKI
                     FSVEGDIKHNSLSDAVDLMNVCKCFFFNSPKNIDILEELYNKLPALKTPLYYIPYFED
                     EN"
     gene            complement(700..1047)
                     /locus_tag="KR294_003657"
     CDS             complement(700..1047)
                     /locus_tag="KR294_003657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241697.1"
                     /translation="MLNLKEIREEIIKKYIGDSLISELTEELKNILITDLQSNPFKSN
                     IELSIIPANIEIFKKIENILIDSKVNLKMGWERILINYILKDLFELNYEINKSCNEPL
                     MFRVIISIDSYDA"
     gene            complement(1265..2221)
                     /locus_tag="KR294_003658"
     CDS             complement(1265..2221)
                     /locus_tag="KR294_003658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HBH0241698.1"
                     /translation="MKKILITGALGQIGSELTIKLRNEYGEQNVIASSRRVKEGNPVC
                     ESGIFEILDVTDKNRFFEIAKKYDVDTIIHLASLLSAVAESKPLEAWNLNMNGLINGL
                     EIAKELDCKFFTPSSIAAFGENSPKNMTPQDTLQRPNTMYGVTKVSGELLCDYYHSKF
                     GVDTRGVRFPGLISYVTPPGGGTTDYAVDIYYEALKNKRYKSYIAEGTKMDMMYMPDA
                     LQSIVDLIEAPADKLIHRNAFNITAMSFSPEEIADSIKKYIPDFVIEYDVDPVRQSIA
                     DSWPNSLDSSSAVKEWNFKFSYDLDKMTKDMLEKLSEKGIGK"
     gene            2664..3032
                     /locus_tag="KR294_003659"
     CDS             2664..3032
                     /locus_tag="KR294_003659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C-GCAxxG-C-C family protein"
                     /protein_id="HBH0241699.1"
                     /translation="MTRPSIYHSQGYTCAEALIKSYNEEHNTDIPISIGSGMGVGMNV
                     GSVCGAVNAAVVIIGYLNGRNSNLDENIARKYSRELLNRVRNKYSSEICVSLKKNKVT
                     CEEIINFTYDALNDMLKNQK"
BASE COUNT         1170 a          424 c          405 g         1212 t
ORIGIN      
        1 attttcatct tcaaagtagg gaatataata taaaggtgtt ttgagagcag gtaatttatt
       61 atataattct tcaagaatat cgatattttt aggggagtta aagaaaaagc atttacatac
      121 attcattaaa tccacagcat ctgaaagtga gttatgttta atatctcctt ctacagaaaa
      181 aatttttttc atattcagta aagatatttg cttagataag attctattat tgtatgtaat
      241 atgttgagat ataaaaggtt gaatgtcaat catcatatta aataactcta agcatttacc
      301 tgtatattta tacactctaa atgaagttag aaggccagtt atatcaaaat caccccaatt
      361 atatattgta acatcatcaa atttacaaaa ccatttataa aaatcatcca taacatataa
      421 aagattagga gcattattga tatctagttg gttcaatttg gttaaatttt tacatttatt
      481 tgaaagtatt ttattgtatt ttggcttaac taaagagtaa taattatcta ttgtattaaa
      541 ttcgttatca actaaaactc caccaataga aattaattcc gcaccattat attcttttgg
      601 tttattttta ttatcatcta gtatattaaa ttcaaagtct ataaataact tgtatttcat
      661 aaatctaaag cacatcctca ggtaaattat ttattgagcc taagcatcat aagaatcaat
      721 agatataatg actctaaaca tcaaaggttc attacaactt ttatttattt cataatttaa
      781 ttcaaataaa tcttttaaga tataatttat aagtattctt tcccaaccca tttttaaatt
      841 aactttagag tctattaata tattttctat ctttttaaat atttctatat ttgctggtat
      901 tatactgagc tcaatattac ttttaaacgg gttagactgt aaatctgtta taagtatatt
      961 ttttaattcc tctgtaagtt cagaaattaa actatcacct atgtattttt ttatgatttc
     1021 ctctctaatt tcttttaaat ttagcaatat tagtacctgc tacttacata gtagcttttc
     1081 ctttcctttt aatactatta ttcatttttg aatcttattt agatatattt taagattaaa
     1141 agtctttagc tatataattt tttacccatt tttaacttat attaacatat tacaggctta
     1201 tatctccacc ctgtttacat tgaggatgga gtatattgcc tattttgata aaaatgatag
     1261 gttgctattt gcctattcct ttttctgata atttttctaa catatctttg gtcattttat
     1321 ctaaatcata actaaactta aagttccatt cttttactgc actactactg tctagagagt
     1381 taggccaaga atcagctata ctttgtctta cagggtctac atcatattct atcacaaaat
     1441 caggaatata tttttttata gaatcagcta tttcttcagg agaaaagctc atagcagtaa
     1501 tattaaaagc atttctatgg atgagtttat cagctggagc ttcgattaaa tccactattg
     1561 attgaagtgc atcaggcata tacatcatat ccatttttgt accttctgct atgtaagatt
     1621 tatatctctt attttttaat gcctcataat atatatcaac tgcataatct gtagttcctc
     1681 caccaggagg cgtaacataa gaaataagac ctggaaatct aacacctcta gtgtctactc
     1741 caaattttga gtgataataa tcacatagta attctccaga aactttagtc acaccataca
     1801 tagtattagg tctttgtaat gtatcttgag gagtcatatt ttttggagaa ttttcaccaa
     1861 aagcagcaat tgaactaggt gtaaaaaatt tacaatccaa ttctttggct atttcaagac
     1921 catttattaa tccattcata tttaagttcc aagcttctag aggtttactt tcagcaactg
     1981 cagaaagtaa agatgctaga tgaattatag tatctacatc atattttttt gcaatttcaa
     2041 aaaaacgatt cttatctgta acatctaata tctcaaatat accagattca catactggat
     2101 taccttcttt tactctcctt gaactagcga ttacattttg ttctccatac tcatttctaa
     2161 gctttattgt taattctgaa cctatttgtc ctaatgcacc tgttataagt atttttttca
     2221 attttacaac ctcctaaggg tttaatttat gtagtactac ttatttttat tttagcaaat
     2281 cttttgttta aatacaaaga attaaagata ataatatacg acttaattga atgaagtgca
     2341 gtaagtgcgt aaaaatttaa agctaatata taatggtcta ttgtataaca ataaaagagt
     2401 agattaaatt attatatata gattgtgtga ctaagtcaca gaaaatagag ctaatttaat
     2461 atataataaa agcatgtcaa gtaaagcttt aaattaaagt aactttatat aaaaagtaat
     2521 ataaattgat aaaattataa atttatttat agtgaatata ggttggattt tatagataca
     2581 aaaatagtat atatgatatg tagaccatta gcatgtttaa agtagcaaaa catataaaat
     2641 aaaatttgaa aggaagtata aaaatgacaa gaccatcaat atatcatagc caaggataca
     2701 cttgtgcaga ggcattaata aagtcttata atgaggaaca caacacagat ataccaatct
     2761 caataggaag tggtatgggg gttggaatga atgttggaag tgtttgtgga gctgtaaatg
     2821 ctgctgttgt tataataggg tatttaaatg ggcgaaatag taatttagat gaaaatatag
     2881 caaggaagta ttcaagagag ctattgaata gagtaagaaa taaatacagc tcagaaatat
     2941 gtgtatctct taaaaaaaat aaagtaactt gtgaagaaat aataaatttc acatatgatg
     3001 ctctaaatga tatgctaaaa aatcaaaaat aattctaaga aacaagtatt ttacattcga
     3061 tagaatactt gtttttttat gatattttta ataagtatta gtttattata atttttaaat
     3121 caattttatt atattttaat tgaaataatc tactttgaaa attactaact gacaaaagaa
     3181 tatgattata gtatagaaaa aatgtaaatt a
//
LOCUS       DAEPKC010000183         3158 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.186, whole genome shotgun sequence.
ACCESSION   DAEPKC010000183 DAEPKC010000000
VERSION     DAEPKC010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3158)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3158)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3158
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.186"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            68..958
                     /locus_tag="KR294_003660"
     CDS             68..958
                     /locus_tag="KR294_003660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBH0241700.1"
                     /translation="MAKLTLEHIKGNTYYIPLPTIVGVYVDGKDAILIDSGNNKDTAR
                     QVLRLLEEHNLNPKLIINTHSNADHIGGNAYLKNQTKCKIATTKIEGYFTENPILESA
                     FLYGGYPSKALKNKFLLAKESEVDYIIPSNGKIVDTELEAISLPGHYFEMIGVRTPDN
                     VLFVADSLTPENIITKYHFFFLLDIDSQFKTLEKLRMLEADFFVPSHSVKTTDIKSLI
                     NINKKKMEEIIDNIKKVCYEPVMIDEVIEKMCDLYNVKLDANQYVLVGSTIRSYITYL
                     YENNMVEYIFDGGKMMIKAA"
     gene            1176..2930
                     /locus_tag="KR294_003661"
     CDS             1176..2930
                     /locus_tag="KR294_003661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp23"
                     /protein_id="HBH0241701.1"
                     /translation="MYIMNKKFKKFSKKLSILILVLTMFLFNNLTANAQIKEDSIIGI
                     DRYETAGLIADRQTYDTVILVNGDKNLSDGLSSSGLAGAINAPILLTKKSEIPKATLN
                     RLDNKSLNVVKKVYIIGGYNTIENSVEKDIKRKGIQVERINGNNRIETSYNVAKKINE
                     VSSVKEVMLTNGFVGEADAMSIAPVVAKNKGAIILTDGKSVPFKTEGLNVYAIGGKSA
                     INEDLVNETKAIRIGGNDRFETNKKVMEKFYNGATDFYITNGYQLVDALTLSPLAKEK
                     PIVLVADGSNKGILKGAKSITKVGGIDANIYKQCLDMIKYNNMDMTPNILKHLTSVEG
                     NEVSEILIESDNLGVVVEKTNTNKFEFDYVSVTNEKNCTFSVYKENSSNNIKNGKLVV
                     SAKKKIDKKDSDLQDMNGDNMINANKDRMVNVIKIGVPDKMYSNFKVDVESGSVELYN
                     IKGGATVDVNDGIANIVDNNVTNPFNINTNSGISGVTAETISSEIKFRANNGIVNVTA
                     TNINGNISLFGSDNKDTFDGIFKLNLKKEPSNLHLKLIGNGINKLPEGWSKDYILGNG
                     QPIIEVKNNGINNISIGE"
BASE COUNT         1326 a          280 c          536 g         1016 t
ORIGIN      
        1 caatttgatt ggaattttca gaaaattaat gctataatta aaagtaaatt taaagggagg
       61 ttataaaatg gctaaattaa ctctagaaca tataaaagga aatacatatt atattccact
      121 ccctacaata gtaggtgtat acgtagatgg taaggatgca attttaattg acagtggaaa
      181 taataaggat acagctagac aagttttaag attattagaa gaacataatt taaatcctaa
      241 attaataata aacactcatt caaatgcaga ccatatagga ggaaatgcat atttgaagaa
      301 tcaaacaaaa tgcaagattg ctacgactaa aattgaagga tattttacag aaaatccaat
      361 attagaatca gcatttttat atggtggcta tccaagtaaa gcactgaaga ataaattttt
      421 attagcaaag gaaagtgaag ttgattatat tataccttca aatggcaaaa ttgtagatac
      481 agaacttgaa gcgatttctc ttccaggtca ttattttgaa atgattggtg ttagaactcc
      541 agataatgtt ttgtttgttg cagatagtct tacaccagag aatataatta ctaaatatca
      601 ttttttcttc ctactggata tagattcaca gtttaagaca ctagaaaaat tgagaatgtt
      661 agaggctgat ttctttgttc caagtcactc tgtcaaaact acagatataa aaagtttaat
      721 taatattaat aagaagaaga tggaagaaat aatagataat attaaaaagg tttgttatga
      781 gccagttatg attgatgaag ttattgaaaa aatgtgtgat ttgtacaatg tcaagcttga
      841 tgctaatcaa tatgtgttgg ttggaagtac aatacgttct tatataactt atttatatga
      901 gaataatatg gttgaatata tatttgatgg tggtaagatg atgataaaag ctgcgtaaat
      961 agtaataatt ttcaaattat atgatgaaat tgttttagta tgactgttat ttgaaaagta
     1021 atataaaaaa atttatataa ataagctaag atgattgata taaagttact gataatttta
     1081 aggtaatata tacgttacta taatattatg ttattatttg taaataaggg gataatttat
     1141 aagcaaatta aagaccttaa tttacaggag gaatagtgta tattatgaat aaaaaattca
     1201 aaaaattcag taaaaaacta agtatattaa ttttagtttt gactatgttt ctttttaata
     1261 atttaactgc aaatgcacag attaaagaag attcaataat aggaattgat agatatgaaa
     1321 cagcaggact tatagcggat agacaaactt atgatactgt aatattagtt aatggagata
     1381 aaaatttatc tgatgggctt tcatcaagtg gattagctgg agctattaac gcaccaatac
     1441 ttttgactaa aaaaagtgaa ataccaaaag ctactttaaa tagactagat aataagagtt
     1501 taaatgttgt aaaaaaagta tatataattg gtggttataa tactattgaa aattcagtag
     1561 aaaaagatat aaaaagaaaa ggtattcaag tggaaagaat aaatggtaac aatagaattg
     1621 aaactagtta taatgtagct aaaaaaataa atgaagtaag tagtgtaaaa gaggtaatgc
     1681 ttacaaatgg atttgtagga gaggctgatg ctatgagtat agcacctgta gttgcaaaaa
     1741 ataaaggagc tataatactt acagatggga aatcagttcc atttaagact gaaggtttaa
     1801 atgtttacgc tataggtggc aaatctgcga taaatgagga tttagtaaat gaaactaaag
     1861 caattagaat cggaggaaat gatagatttg agaccaataa aaaggtaatg gaaaagtttt
     1921 ataatggagc tacagatttt tatataacaa atggatatca attagtagat gcactaacat
     1981 tatctccttt agccaaagaa aaaccaatcg ttttagttgc tgatggaagt aataaaggta
     2041 ttttaaaagg agctaaaagt ataacaaaag ttggaggtat tgatgccaat atatataaac
     2101 agtgtttaga tatgattaaa tataataata tggatatgac tccaaatatt ttaaaacact
     2161 taacttcagt tgaaggaaat gaagtttctg aaatacttat agaatcagat aatttaggtg
     2221 tggttgttga aaagacgaat accaataaat ttgagtttga ttacgtaagt gtaactaatg
     2281 aaaaaaattg tactttttct gtatataaag aaaattcttc taataatata aaaaatggaa
     2341 agctagttgt aagtgctaag aaaaaaatag ataagaaaga tagtgatttg caagatatga
     2401 atggcgacaa tatgataaat gcaaataaag ataggatggt aaatgtgata aaaattggag
     2461 ttcccgataa aatgtattct aattttaaag tagatgttga aagtggttca gtagaacttt
     2521 ataatattaa aggaggagct actgttgatg tcaatgacgg aattgctaac attgttgata
     2581 acaatgtaac aaatcctttc aatataaata ctaatagtgg gatttcaggt gtaacagctg
     2641 aaactatatc atctgaaata aaatttagag caaacaatgg aattgtaaat gtaacagcta
     2701 caaatataaa tggcaatata agtttatttg gaagcgataa taaagatact tttgatggaa
     2761 tatttaaatt aaatctgaaa aaagaaccat caaatttaca cttgaagtta attggaaatg
     2821 ggataaataa attgccagaa ggttggtcta aagattatat tttaggaaat ggacaaccaa
     2881 ttattgaagt taaaaataat ggcataaata atatatcaat tggagaataa aaacatatga
     2941 aaataaagtt tatatagttt taaaaattat agaattttaa aatatttata tatattcttt
     3001 aaataaaaaa ttatttttta agtgataatt aagtgtttat cgataaggct atggttgtaa
     3061 aaatcatagc cttattttta tattataaat aaattagagt atttatcaat tcatagtaga
     3121 taaaattgaa attaaatata acaacaaaaa atgaaaat
//
LOCUS       DAEPKC010000184         3149 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.187, whole genome shotgun sequence.
ACCESSION   DAEPKC010000184 DAEPKC010000000
VERSION     DAEPKC010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3149)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3149)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3149
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.187"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(21..197)
                     /locus_tag="KR294_003662"
     CDS             complement(21..197)
                     /locus_tag="KR294_003662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241702.1"
                     /translation="MFRDKMDRCTHMLTAYIGSSYDYCDFIDTQLDDFILEYGENVVE
                     SCLHQVMVLVSKYN"
     regulatory      complement(251..347)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            1144..1545
                     /locus_tag="KR294_003663"
     CDS             1144..1545
                     /locus_tag="KR294_003663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNHCP domain-containing protein"
                     /protein_id="HBH0241703.1"
                     /translation="MNYKNRKRAYYQENSCMDNFICKNCGCLVVPEGAGTQHRNHCPH
                     CLHSLHVDIIPGDRAADCDANMEPIGVWVRKNGEWAIIHRCTRCGHLSSNRIAADDNS
                     VKLMSIALKPLAQPPFPLERIIEKLEKEETE"
     gene            1542..2609
                     /gene="rsgA"
                     /locus_tag="KR294_003664"
     CDS             1542..2609
                     /gene="rsgA"
                     /locus_tag="KR294_003664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HBH0241704.1"
                     /translation="MNGMKQINLQDYGLNRNFITQSMEYHDLYLARIISQEKNFYQAV
                     CVNGVLFAEVSGKLRFEATIQSDFPTVGDFVMLDRCNNKNGNAIIHHVLHRKSLFVRK
                     AAGKVNEEQVVAANIDIVFLCMSLNKDFNIHRLERYLSLTWESGAIPVVVLTKSDLCD
                     NVHRKLQVVNSIALGVDVVVTSSIEPDGYKQISKYIKPGCTVALLGSSGVGKSSLINC
                     LMGGEFLNTKEIRIDDDKGRHATTRRELFLISGGGIVIDTPGMRELGMWDVSEGLDKS
                     FADIEAYFGKCHFRNCTHTSEPGCAIWEAIAHQELSPKRWESYRRLKTEAVFADNKSE
                     YLAKKEKKFKNISKINKKIRR"
BASE COUNT         1126 a          388 c          534 g         1101 t
ORIGIN      
        1 ctctagaaaa ccaaatctat ttaattatac ttacttacta ataccatcac ttgatgcaaa
       61 caagattcta ccacattttc tccgtactct agtataaaat catctagttg tgtatctata
      121 aaatcacaat aatcatatga actaccaata taagcagtca acatatgtgt acatctatcc
      181 attttatctc taaacatata tattattatc cccctaaaaa actttcataa aaacaaaaag
      241 aatatctctt tttggcaact ggctgacata actcatagtt tattttataa gcgttagtcc
      301 ctatagcttt gcgtcactaa atttctctag ttttgccgat ttagttttat tctacaatta
      361 caataataca atagaattgc ttattattca atatacttat ttgaaaatta aataaattta
      421 caaatatgaa cgttatttta tatcaaaaaa aatagactat gcatgtagaa tatatggaaa
      481 aacttgattg taggttttgt atgaaaagac agttgttatt aatttaagtg agataaattg
      541 agcaacaggc ataaaatgag aaaacaaata atagcagtta atttttatta ttaatactag
      601 gtgaacatta aatttcaaaa taccactaga ttttatagaa taagaaaatg agacaaacat
      661 aaatatatga atatattaaa ttatacttga acatacttat attttatgat aaaatttcaa
      721 taataattat tagtgaagga gtgtcttgcc tgatgtcaga gttatatata atggtaacca
      781 acaaataaat agttggagac gcatatgggt tctgtttaat cagaattttt aagtgtattt
      841 ttgatacatt tgattgttgt gtcttactct gcctttatag ataactaaca ttagacaaca
      901 aataataata ttacatatta ctttgttaaa ttgtggtgta gtgggcttta atctgctaca
      961 cttttattaa ttttacacag tattattttg aatataatta tgttgaaata gaagatacta
     1021 aattttctag tccacagggg ttttctgttt ttgtgtaggt aaatatgtat accacataaa
     1081 aaggcagata taaatacctg tggacttttt ttgtagaaaa tacacgatac ggaggaaata
     1141 aaaatgaatt ataaaaatag aaaacgagct tattatcagg aaaattcctg tatggataac
     1201 tttatttgca aaaattgtgg ttgccttgta gttcctgaag gagctggtac acaacataga
     1261 aatcattgtc cacattgttt acatagtctt catgtagata tcattcctgg tgaccgtgct
     1321 gcagattgtg atgctaatat ggaacctatt ggagtgtggg tgagaaaaaa tggtgagtgg
     1381 gcaattattc atcgttgtac acgctgtgga catcttagtt ctaatcgtat tgcagctgat
     1441 gataattcag tgaaattaat gtcaattgca ttaaaaccac tggcacagcc ccctttccca
     1501 ctagaaagaa tcattgaaaa gttggaaaag gaggaaacag aatgaatggt atgaaacaaa
     1561 tcaatttaca agactatggt ctaaatagaa attttattac tcaaagtatg gaatatcatg
     1621 atttatacct tgctcggatt atctcgcagg aaaagaactt ttatcaagct gtatgtgtaa
     1681 atggtgtact gtttgcagag gtttcaggaa agctgcgttt tgaggctact atacaatctg
     1741 attttcccac agttggtgat ttcgttatgt tggatcgttg caataataaa aatggtaatg
     1801 ctattattca tcatgtgctt catagaaaaa gcttgtttgt gcgtaaggct gctggaaagg
     1861 taaatgagga gcaggtggtt gcagctaata ttgacattgt ttttttgtgc atgtcactga
     1921 ataaggattt taacattcat agattggaga ggtatctgtc tttaacatgg gaaagtggag
     1981 ctatcccagt agtagtactt actaaatcag acttatgtga caatgtgcat cgtaaattac
     2041 aagtagttaa ttctatagcc ttgggtgtag atgtagttgt tacctcatct atagagccag
     2101 atggttataa acagatttct aagtatatta aaccaggctg tactgttgcc ttacttggtt
     2161 cttcaggagt tggaaaatct tcattaatta attgtctgat gggtggagaa tttttaaata
     2221 caaaggaaat tcgcatagat gatgataaag gaagacatgc cacgactaga cgagagctat
     2281 ttttaatttc aggtggtggt attgttattg acacaccagg tatgagagag ttgggaatgt
     2341 gggatgtttc agaaggttta gataaaagtt ttgcagatat agaagcttat ttcggaaaat
     2401 gtcattttcg taattgtact cacacctcag aaccaggctg tgctatctgg gaagctattg
     2461 ctcatcaaga actttcgcct aaaagatggg aatcctatcg taggcttaaa actgaagcag
     2521 tatttgcaga caataaaagc gaatacttag caaaaaaaga aaagaaattt aaaaatatct
     2581 caaaaataaa taagaagatt agaagataag tgtagttttt ttgttcattc tatgagtcta
     2641 tatactatta atatattaaa tttgccatca atttgttact ttaatgtgat tttgatggca
     2701 aatttggttt gtggtattat ttaaagcaat ttattaattt ttttaataaa gtttgatttt
     2761 ttatatgatg atatatacat gtgataatgt atacatattt gttacgatag gctcctttat
     2821 aaagaggtct tatgtaagat aagaaaaggc atatttatac taatacataa tagagtatat
     2881 gcttatgtat gatagagatg tttcttaaga gcaaaactgc aatattgcta atttataaag
     2941 taaaaatata tgaattataa aatacaaata atatatttat aaaaattatt gttttaattt
     3001 ataataaaaa ttttttgttg aaaataatgc tcgaacctat aaaactatta actaatattt
     3061 gtaaatgtat acttttgatg ataaaatata attaagttaa gttggttttt ataaacataa
     3121 atttatttta aggaggtgaa ataaatgaa
//
LOCUS       DAEPKC010000185         3068 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.188, whole genome shotgun sequence.
ACCESSION   DAEPKC010000185 DAEPKC010000000
VERSION     DAEPKC010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3068)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3068)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3068
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.188"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..860
                     /locus_tag="KR294_003665"
     CDS             <1..860
                     /locus_tag="KR294_003665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HBH0241705.1"
                     /translation="PFMNYTFIFNESKYNGNINKISLGNFNSISIVYSTVLVSVWIAI
                     TIFYLVYTLLKYIKLKNMINDLSYDVEDDKIKNLYENLLKELKINKKIRLKYSYEVES
                     PVFFNSCVILPPSDYTLKELNWIFRHELMHFKSKDLYIKYLVIFLKCVYWFNPFVYIM
                     EKFIDLDCEFYCDERVLKNCTIEEKQDYALTIISAMRKGSNSSNKFVAGLHKESDIKK
                     RVFSMFNEKYRNGILIAVILCLLSSITYFKIDLITTKSIFYPLSKQTPIENRTNSKPT
                     YQINVYIDN"
     gene            1216..1785
                     /locus_tag="KR294_003666"
     CDS             1216..1785
                     /locus_tag="KR294_003666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrpB family protein"
                     /protein_id="HBH0241706.1"
                     /translation="MKKKLEDMTLEELWNLFPIFLTTHKECWKNWFKEEQYRLTGILP
                     MQKIVRISHIGSTSVSTIYAKPIVDILIEIIPDYNMKDIKDLIESNGYICMSESSSRL
                     SLNKGYTVDGFEERVFHLHIRYVGDNDELFFRDYLIDHPDVAKEYEKLKLDLWKKYEH
                     NRDAYTDSKLDFVREFTEKAKVLYFNRYN"
     gene            complement(2121..>3068)
                     /locus_tag="KR294_003667"
     CDS             complement(2121..>3068)
                     /locus_tag="KR294_003667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBH0241707.1"
                     /translation="ISALIKLLFWFLIHIFLKNRLVNIKQYLSNKIWIFIDMVCISSF
                     LSILIAIILPPTNLIPMGSNKNIILGNLPYGTYLIILSAILANIGVILLLQPLIENVK
                     MKIEKQANHLKEKYYNLLENQQIQIRKMRHDMNNHFQMIESYLEIEDIAGAKKYFNQL
                     KIGIGTLSGKQFCKNQALNSILNLRHTSLEENGVDVHFNIDIDNHLGIEPIDLCTIFS
                     NSLDNAIEASLKIPDLSNRKVVLKARCEKEYFSYLLTNNKVNPINRKQELFISDKKDS
                     NSHGYGIENIREIVNKYNGKLDISYTENEFSLFLYIRLF"
BASE COUNT         1175 a          314 c          455 g         1124 t
ORIGIN      
        1 taccatttat gaattatact tttatattta atgagtcaaa atataatggt aatattaata
       61 agataagttt aggcaatttt aatagtattt ctattgtata tagtactgtt ttagtctctg
      121 tttggattgc tattacgata ttttatttag tttatacttt attgaaatat attaagctta
      181 aaaatatgat aaatgatttg tcttatgatg ttgaggatga taagataaaa aatctttatg
      241 aaaatttatt aaaagagctt aagataaata aaaaaatacg gcttaaatat tcatatgaag
      301 ttgaaagtcc agtatttttt aattcgtgtg tcattttacc accaagtgat tatacattaa
      361 aagagttaaa ctggatattt aggcatgagt tgatgcattt taagagtaaa gacctttata
      421 ttaagtattt ggtgatattt ttaaaatgtg tttattggtt taatcctttt gtgtatataa
      481 tggagaagtt tatagatttg gattgtgaat tttattgtga tgaaagagtt ttgaagaatt
      541 gtacgataga agagaagcag gattatgcat tgacaataat tagtgcaatg agaaaaggtt
      601 caaatagttc aaataaattt gtggctggat tacataagga gtcagatatt aaaaaaagag
      661 tgtttagtat gtttaatgaa aagtacagaa atggtatttt gatagcagtt attttatgtt
      721 tattatcttc tattacatat tttaaaattg atttaattac tactaaatca atattttatc
      781 cactttcaaa acaaacacct attgaaaaca gaactaattc aaaacctaca tatcagatta
      841 atgtttatat agataattaa aaaatacaaa gtttaacaag agattaatat aaataatttt
      901 aataagtatc tttcacatat gttaaattta ctttaattat attaaagcca atgaattatt
      961 ctttagaagc tccaatgcca gtaaatacag gtaaagaaaa atattttact acaattgcag
     1021 attaaaaagt gttctaatat ttaaagaaat acacaagtgt aagaagggta aaaatctgtt
     1081 ataatacatt aaaaactaaa tttagaaaaa tttacataat tagaaaaatg atttgataaa
     1141 aaataaagtt aaatattaac taagtaaatt tgaaaaagaa aaaatataaa gtacaaattt
     1201 aaaaggaggt aactaatgaa aaagaagttg gaagatatga ctttagagga gttatggaac
     1261 ttgtttccta tatttttgac tactcacaaa gaatgttgga aaaattggtt taaagaagaa
     1321 caatatagac taactggaat attgccaatg caaaaaattg ttagaataag tcatattgga
     1381 agtacttctg tgagtacgat ttatgccaag cccattgttg acatactgat tgagataatt
     1441 cctgattata atatgaaaga tattaaagat ttgattgagt cgaatggata tatttgtatg
     1501 tctgagagca gtagtaggct ttcacttaat aaagggtata cagtagatgg gtttgaagaa
     1561 cgagtttttc atttgcatat aaggtatgta ggtgataatg atgagttgtt ttttagagat
     1621 tacttaattg accacccaga tgttgcaaag gagtatgaaa aacttaagtt ggacctttgg
     1681 aagaagtatg agcataatcg tgatgcttat acagatagta aactagattt tgttagggag
     1741 tttactgaaa aggcaaaggt gttgtatttt aatagatata attagaaata ggtacaatta
     1801 gatatttatc ttatatatcg tattatattt tttaagaaag taattaatag aaaaaggggt
     1861 tgtttcaaaa tggagagata aatccctttt tcattgttga aaggataaaa atatatttga
     1921 tttcatgtaa aaaagagtgc ctcatcaact aaaaagttta ttttgagaca cacacatttt
     1981 tactaaggta aataaaatat cacatttgat taaattttaa gttaatgaat atatgtgtaa
     2041 atatttaatt ataagttatt ataattttac atagtatcaa acaatctaat ttgtattata
     2101 taagataatc taattttaga ctaaaataat ctaatataaa gaaataaaga aaattcattc
     2161 tcagtataag agatatccaa ttttccattg tacttattaa caatttctct aatattctca
     2221 ataccatatc cgtgagaatt actatctttt ttatctgaaa taaatagttc ttgttttcta
     2281 ttgataggat ttaccttgtt gtttgtcaat aaatagctaa aatactcctt ctcacaacgt
     2341 gcctttaata ccacttttct atttgacaaa tcaggaatct tcaaagatgc ttctatagcg
     2401 ttatctaaag aatttgaaaa aatagtacat aaatctatag gttctatacc caagtgattg
     2461 tctatatcta tattaaagtg cacatcaaca ccattttctt ccaaacttgt atgacgaaga
     2521 tttaaaattg agttaagagc ttggtttttg caaaactgtt tgccactaag agtacctata
     2581 cctattttta actgattaaa atacttttta gctccagcaa tatcttcaat ttctaaatac
     2641 gattcaatca tttgaaagtg attattcata tcatgtcgca ttttgcgtat ttgaatttgt
     2701 tgattttcta gtaagttata gtatttttct tttagatgat ttgcttgttt ttctatcttc
     2761 atctttacat tttcaatcaa tggctgtaaa agaagtatca caccgatatt tgccagaatt
     2821 gctgacaaga tgattagata agtgccataa ggtaagttgc ctaagataat attcttatta
     2881 ctacccatag ggattaaatt agtaggtggc agaataatag caattaatat tgataaaaat
     2941 gaagatatac ataccatatc aataaaaatc catattttat ttgataagta ttgttttata
     3001 ttgaccaatc tattctttag gaaaatatgt attaaaaacc aaaataataa tttaattaga
     3061 gcagaaat
//
LOCUS       DAEPKC010000186         3052 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.189, whole genome shotgun sequence.
ACCESSION   DAEPKC010000186 DAEPKC010000000
VERSION     DAEPKC010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3052)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3052)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3052
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.189"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            1303..1692
                     /locus_tag="KR294_003668"
     CDS             1303..1692
                     /locus_tag="KR294_003668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBH0241708.1"
                     /translation="MTIKKLPQSELKIMKFIWKSDSKVTSRDIVLGMEQKYQWKQTTT
                     LTLLSRLVVKRFLNSQKIDKYTHYEVLIKEKEYIGVETRDFFRNIHDSSIKSLLLSLH
                     ENINLSKDDILLIEEWIKNLKEEEKDV"
     gene            2562..3032
                     /locus_tag="KR294_003669"
     CDS             2562..3032
                     /locus_tag="KR294_003669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase/bleomycin resistance/dioxygenase
                     family protein"
                     /protein_id="HBH0241709.1"
                     /translation="MKYQVSLLAVKDIEVSKKFYKELFEQEIELDLGKNVTFKGGFAI
                     QEDFAWLTGINPDTIIQKSNNMELYFEVDDFDEFIEKLNYYKDVEFVHKPLKHEWQQR
                     VVRIYDPDKHIIEIGESMEVIARRYLSEGYSVEETSKIIQHPIKFVKQCENSKE"
BASE COUNT         1366 a          176 c          543 g          967 t
ORIGIN      
        1 tgtaactatt gtaagtatat tttattatag ttatttattt aaagtacgat aaatgtttta
       61 aattgaagta ttttgcgcca ttgagttcta ctaaagtaga gtttttgtgt agtattttta
      121 gaaataacat atatatatat gtatttatgt tgaaatatat gggaaattta taatataatt
      181 aatgaaaaaa tttaaacttt gtaatatata aataaaaaaa ctctaaaata gaaggatata
      241 attatataga atgtttcaat taaacaagtc aaaaattata atcttaaaat taacattatt
      301 cttaagaagt aagaaattta agaagtaaaa agtttagtga taagtggtaa taagcaagaa
      361 atttagaaag taggaagttt agttataagt ggtagtaagt aagaaattta ggaagtggga
      421 agtttagtta taagtggtag taagtaagaa atttaggaag tggtaagttt agttataagt
      481 agtagcaagt aagaaactta ggaagtggga agtttagtag taataattta tagcaagtaa
      541 gaaatttagg aagtaggaag tttagtaata atttgtagca agtaagaaat ttagaaagta
      601 ggaagtttag taataattta tagcaagtaa gaaatttagg gagtaggaag tttagtaata
      661 atttatagca agtaagaaat ttagggagta ggaagtttag taataatttg tatcaagtaa
      721 gaaatttagg gagtaggaag tttagtaata atttatagca agtaagaaat ttagaaagta
      781 ggaagtttag taataattta tagcaagtaa gaaatttaga aagtaggaag tttagtagta
      841 atttatagta agtaagaaat ttagtaagtg agaagtttag ttataattta tagtaagtaa
      901 gaaatttagt aagtgagaag ttcagtaata agttgtagta aataaaaagt ttaggaagta
      961 ggaagttcag taataagttg tagtaaataa aaaatttagg aagtaggatt tactgaaata
     1021 caaatattta aaatcaaaga gtttaaaaga aaggagagct actggacaag tatccaaaat
     1081 agatagctga gtacaaaata tttcataaaa ttaagcaata taatacaaga gaattttgac
     1141 attatttata tatatttacc gtgtacaaat agctaaattt aggattaaga ttgaaaaata
     1201 tcttataagt ctgagcttat ataaatccgt ataagatgta tttaatcgaa aaattttatt
     1261 atggatattg cttgtctata ttctgagtag caaggtttta tcatgactat aaaaaagttg
     1321 ccacaatcag aattaaagat aatgaaattt atatggaaat cagattccaa agtaacatct
     1381 agagatattg ttttaggaat ggagcaaaaa tatcaatgga aacaaacgac aactttgact
     1441 cttttatcta gattagtagt aaaaagattt ctaaattctc aaaagataga taaatatacg
     1501 cattatgaag ttttaattaa agaaaaggaa tacataggag ttgagacaag agattttttt
     1561 agaaatattc atgattcttc tataaaaagt ttattgttgt cattacatga aaatattaat
     1621 ttgagcaaag atgatatttt acttattgaa gagtggataa aaaatctaaa agaagaggag
     1681 aaagacgtat aagcaaacgt atttcttata gcatcaatat aaagtgtatg taagtgtatt
     1741 tatgtaatat attagtctac ttaagtaata tgacaaatga ttataagtgg attatgatac
     1801 tataatgtga atctaaataa attaaatata aattaatagt ggatattcta tttaattaaa
     1861 tttaaaaagc tacctttact tataagtata attaaggtag ctttttaaat agaggtagtg
     1921 taattaaaga gaatttttaa atataaattg tgaagcttta atatagatga taatatatat
     1981 tttgcaaata tgacacagtg ttttcgtatt taagatgata aaataaatag gaattaatga
     2041 agatattgaa aaaataaaaa taaaggatta atataagata ttaaagagat agagataaaa
     2101 gtgttaacag aagatattga aaaaataaaa gattgatata agatactgaa gaggtagaaa
     2161 taaaagtatt aatagaagat attgaaaaaa taaaaacaaa agattgatag aaagtactga
     2221 atagatagag ataaaagtgt taatggaaga tattgaaaaa ataaaagatt gatataagat
     2281 actgaagaga tagaaacaaa agtattaata gaagatattg aaaaaataaa aacaaaagat
     2341 tgatagaaag tactgaatag atagagataa aagtgttaat agaagatatt gaaaaaataa
     2401 aagattgata taagatactg aagaggtaga aacaaaagtg ttaatagaag atactaaaaa
     2461 agtaaaaata aaggattaat aaaaggtact gaagagatag agaaaaaaat gttaatagaa
     2521 gatactgaaa aaatagaaat aaaaaattag gaggaaaatt tatgaaatat caggtttcat
     2581 tattagcagt gaaggatatt gaagtatcaa aaaaatttta caaagaatta tttgagcaag
     2641 aaattgaatt ggacttaggt aaaaatgtaa catttaaagg aggatttgct atacaagaag
     2701 acttcgcatg gcttacaggg attaatccag atacaattat acaaaaatca aataatatgg
     2761 aactttattt tgaggttgat gattttgacg aatttattga aaaactcaat tattataaag
     2821 atgtagagtt tgtccataag ccactaaaac atgaatggca acaaagagta gtgcgtattt
     2881 atgacccgga taagcatatt attgagatag gagagtctat ggaagttata gctagaagat
     2941 atttatctga gggatactct gtagaagaaa cttctaaaat aattcaacat ccaattaaat
     3001 ttgtaaagca gtgtgaaaat agtaaggaat gattgtttaa attataatta tt
//
LOCUS       DAEPKC010000187         3042 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.190, whole genome shotgun sequence.
ACCESSION   DAEPKC010000187 DAEPKC010000000
VERSION     DAEPKC010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3042)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3042)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3042
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.190"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            57..908
                     /locus_tag="KR294_003670"
     CDS             57..908
                     /locus_tag="KR294_003670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase"
                     /protein_id="HBH0241710.1"
                     /translation="MKNIISAKELISKLEKNDNLVVIDCRFDLINRTYGIDSYKKGHI
                     KGSFILDIDKDLSSPTKEHGGKNPLQDPLILKEKLEKMGVDNDTTIVTYDDGDLNGAC
                     RLFFQLKHLGLKNVYVLDGGITSFVKEGGELEEKVNIPSCTGKEIRPNINNGLVVPME
                     YVKSKLYKKDTVIIDCRANERYQGLVEPAYSKAGHIPSAKNYFCKDLIKSDFENGSLK
                     DIEFLKKFFKDLNNYDEVILSCGSGISACVNSLALRELDIPHKIYIGSFSDWISYDDN
                     EIKTGQE"
     gene            complement(1041..2654)
                     /gene="ggt"
                     /locus_tag="KR294_003671"
     CDS             complement(1041..2654)
                     /gene="ggt"
                     /locus_tag="KR294_003671"
                     /EC_number="2.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyltransferase"
                     /protein_id="HBH0241711.1"
                     /translation="MKFNAYQHKYSSIRNVVYAKNGAVATSTPLASQAGLEILKKGGN
                     AVDAAVATAATLAVVEPTSNGIGGDAYALVWIEEEKRLYGLNSSGFAPENMELKNYNN
                     MKEMPKYGFGAVTVPGIPAAWSELNKKYGKLSLMECLSPAINYAREGYVVSPNVAKVW
                     KKSYELYEKELIGEEFKPWFDTFSKDGKAPEAGDIFICEEQASTLEEIANTQAESFYR
                     GRLADKIDEYSKKFNGAIRKSDLECFYPTWVEPISTEYKGYKIFEIPPNGHGITVLMA
                     LNILKELELEGNIENVEDIHKIIESLKLAFADSKTYVTDIEHMKVKIQELLSQEYAKK
                     RSLLIDNKEALYPTAGEPYCGGTVYLCTADKDGNMVSYIQSNYINFGSGIVIPRTGIA
                     LHSRGNNFNLDPKHHNVVKPFKKPYHTIIPGFLGKEDKAIGPFGVMGAFMQPQGHIQV
                     LTNMIDFGLNPQEALDAPRWQWIKGKEIEVEPEMPKHIIDSLIEKGHEIKVIHDTVDM
                     GRGQIIFKTEQESYICGTESRCDGHIAVY"
BASE COUNT          994 a          501 c          415 g         1132 t
ORIGIN      
        1 gttaataatt aatataaatt aaaataaaga taatataaac acaggaggta cattctttga
       61 aaaacattat ttcagcaaaa gaacttatat caaaactaga aaaaaatgat aatctagttg
      121 taatagattg cagatttgat cttatcaata gaacttatgg tattgattct tataaaaaag
      181 gacacatcaa aggcagcttt atcttagata tagacaagga tttatcatct cctacaaaag
      241 aacatggtgg taaaaatcct ttacaagacc ctttaatact aaaagaaaaa ttagaaaaaa
      301 tgggtgttga taacgacact acgattgtaa cttatgatga tggagattta aatggagctt
      361 gcagattatt tttccaatta aaacatttgg ggcttaaaaa tgtctatgta ctggatgggg
      421 gaataacatc tttcgtaaag gaaggtggag aattggaaga gaaagtgaat ataccaagtt
      481 gtacaggtaa ggaaattaga ccaaatataa acaatggttt agttgttcca atggaatatg
      541 ttaagtctaa attatacaaa aaagatactg taataataga ttgccgtgct aatgagagat
      601 accagggttt agttgaacct gcttactcaa aagctggtca tataccaagt gcaaaaaatt
      661 atttttgtaa ggatttaata aaaagtgact ttgaaaatgg ctcacttaaa gatatagaat
      721 ttttaaaaaa attctttaaa gatttaaata attatgatga agtaatttta tcttgtggtt
      781 cagggatatc tgcttgtgtt aacagtcttg ctcttagaga actggatata cctcacaaga
      841 tttatattgg tagctttagt gactggatta gttatgatga caatgaaatc aaaactggtc
      901 aagaataagg ctcataatct atataaaatc agcatatgat agcttaaatt ttgtaaaggc
      961 gtcagtcatt gtagactttc gcctttacta attatttcat atactcttta aatttattat
     1021 atatatttta gttgataata ttaataaact gcaatatgac catcacatct tgattccgtc
     1081 ccacaaatat aactttcctg ttctgtttta aatattattt gacctcgtcc catgtcgaca
     1141 gtatcatgaa ttacttttat ttcatgaccc ttttcaatta atgaatctat tatgtgcttt
     1201 ggcatctctg gttcaacttc tatttccttt ccttttatcc actgccatct tggagcatct
     1261 agcgcctctt gtggatttaa tccaaaatca atcatatttg ttaacacttg aatatgtcct
     1321 tgtggttgca taaaagctcc cattacacca aatggaccta ttgctttatc ttctttacct
     1381 aaaaatccag gtattatagt atgataaggt tttttaaatg gttttactac attgtggtgt
     1441 ttagggtcta aattaaaatt atttcctcta ctatgtaaag caatcccagt tcttggtatc
     1501 acaattcctg aaccaaaatt tatgtaattg ctctgtatat atgaaaccat atttccatcc
     1561 ttatctgcag tacaaaggta tactgtacca ccacaatatg gctctcctgc agttggatac
     1621 aaagcctctt tattgtcaat caataaactt ctttttttag catactcttg gcttagtaat
     1681 tcctgaatct ttaccttcat atgctctata tcagttacat atgttttaga atctgcaaaa
     1741 gctaatttta aactctctat aattttatgt atgtcttcta cattttctat atttccttct
     1801 aattccaatt cttttaatat gttaagtgcc attaaaactg ttattccatg accatttggt
     1861 gggatttcaa atattttata tcccttatat tctgtactta taggttctac ccatgttgga
     1921 taaaaacact ctaagtcact ctttcttata gccccattaa attttttaga atattcatct
     1981 attttatcag caagtcttcc tctataaaag ctttcagcct gagtatttgc tatctcttct
     2041 aatgtacttg cctgttcttc acatataaat atatctccag cctctggagc tttaccatct
     2101 ttagaaaatg tatcaaacca tggtttgaac tcttctccaa taagttcttt ttcatagagt
     2161 tcatatgatt ttttccatac cttagctaca ttaggagata ctacgtatcc ctctcttgca
     2221 tagtttatcg ctggagataa gcattccatt aagctaagtt taccatattt tttatttaat
     2281 tctgaccaag ctgctggtat tccaggtaca gttactgctc caaacccata ttttggcatt
     2341 tctttcatat tattataatt ttttaattcc atattttctg gagcaaagcc actagaattt
     2401 aaaccataca atcgtttttc ttcctctatc caaacaaggg catatgcatc tcctccaatc
     2461 ccattgcttg taggttctac tactgctaat gtggcggctg ttgcaactgc tgcatcaaca
     2521 gcatttccac ccttttttag tatttcaagt ccagcttgag atgctaatgg tgttgatgtt
     2581 gcaactgctc catttttagc atacacgaca tttcttattg atgagtattt atgttggtag
     2641 gcattaaact tcataaattt cagctcctcg tcatttttta tttgatattc tgcttagatt
     2701 tattatataa catcaattaa tgtaactgat acaaaatgat ataaaatata gactttttcc
     2761 taactttaat tttatcttta aataaatatc ttaaactcaa ttctagtatt ttctatctgc
     2821 acttaaataa gttattttat tcaaaacata tatctaattc ttttaactta aaaataattt
     2881 attcttttat catgtttaga gcatatttta aagttaaaaa ataatatata aaatatccta
     2941 taaaataaat gactagagtt atgataattg gtacaagtaa tgaccttggt ataaactttt
     3001 gtgctataga catagcaaat aaattatgaa ctgtacctac aa
//
LOCUS       DAEPKC010000188         3014 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.191, whole genome shotgun sequence.
ACCESSION   DAEPKC010000188 DAEPKC010000000
VERSION     DAEPKC010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3014)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3014)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3014
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.191"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            1..1845
                     /locus_tag="KR294_003672"
     CDS             1..1845
                     /locus_tag="KR294_003672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HBH0241712.1"
                     /translation="MQKRILRNFIFTGKNILSKLVFIIKYNFSTLILFELFHKGLALF
                     FIWPSIRYIFDILIKSLHIVYLNMDNFIKVLTNPMSIVLIILSVIILAFYAFFEFTSV
                     IICFNKSIKYEKIGLFELFKISFENSIKLLYPKNILLFIFVILIIPLVNTVLISGFIG
                     KIQIPEYILDYIKSDIILNIIYMIFLLIIYISVIRWIFSIHEITLNTENFKRARKESV
                     NLIKGKIIRTIIYSLILSLVVAIIGYAIYHSGIIFIGIWTKYCTDMEFLKNVFINRCI
                     AFEEYFRLILSIFIFILDIGFISATYYQYKGVNIFKNNIKKEKKSISKIVFNLVLILL
                     ISYIESVAFSSHINGMFNTSFSFYTTAIAHRAGAEMAPENTLAAIEEASHAKADYAEI
                     DVQETKDGELIVLHDSNFKRTTGVDKNVWDVNYNEVKTYDAGSFYYYGKGYYDEKFVG
                     EKIPTLKEMIKYSKGKVKLLIEIKLNGHEKGDVVKKVVQLIKENNFENQCIVASMDKT
                     ILQKVKKLDENLLTCYFMAIAYGDFSKLNYVDIYGIESTFVNKTVVEKIHKMNKKIFV
                     WTVNSDSLIEKMLDLNVDSIITDNPYLIESAIYWKKNGFISQVSDYLF"
     gene            2167..2751
                     /locus_tag="KR294_003673"
     CDS             2167..2751
                     /locus_tag="KR294_003673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HBH0241713.1"
                     /translation="MTEREKMLAGELYDCGDIELLTQWHKAKDLVRDYNQTDSLDLEK
                     KEKILNELLGGKGKNLWITAPYYVDYGNNIYFGNNCEVNMNCTFLDDNKIIIGDNALI
                     APNVQIYTAFHPTNAGDRFGNAKEDGSFEFCKTQTAPVTIGDNVWIGGGAIIMPGVTI
                     GDNVVIGAGSIVTKDIPSNMIAYGNPCRIIRENK"
BASE COUNT         1170 a          280 c          457 g         1107 t
ORIGIN      
        1 atgcaaaaga gaattttaag aaattttata tttacgggta aaaatatttt aagtaaactt
       61 gtttttataa taaaatataa ttttagtaca ttaattttat ttgaattatt tcataaagga
      121 ttagccttat tttttatatg gccatctatt agatatatat ttgatatttt aataaaaagt
      181 ttacatatag tctacctaaa tatggataat tttataaaag ttttgaccaa tcccatgtca
      241 atagttctga taatactatc agttataata ctagcttttt atgcattttt tgaatttacc
      301 tctgtaatta tttgttttaa taaatcgata aaatatgaaa aaatagggtt atttgaactc
      361 tttaaaatat catttgagaa ctctataaaa ttgttatatc ctaaaaatat actattattt
      421 atatttgtga tattaataat tccattagta aatacagttt taatttcagg gtttatagga
      481 aaaatacaaa taccagagta catattagat tatataaagt ctgatataat tttaaatata
      541 atctatatga tttttctttt aataatatat atttcggtta ttagatggat ttttagcatt
      601 catgagataa ctttaaatac agaaaatttt aaaagagcaa gaaaagaaag tgttaatctt
      661 ataaagggaa agattataag aacaattatt tattcattaa tattatcttt agtagtagct
      721 attattggat atgcgattta tcatagtgga attatattta taggcatatg gactaaatat
      781 tgtactgata tggaattttt gaagaatgta tttataaata gatgtattgc atttgaagaa
      841 tattttagat tgattttatc aatattcatt tttatattgg acattggatt tatctcagca
      901 acttattatc aatataaagg agtaaatatt tttaaaaata atattaaaaa agagaaaaaa
      961 tctatatcaa aaattgtttt taatttagta ttaatattat tgatttctta tatagagtca
     1021 gttgcatttt cttcacatat aaatggtatg tttaatacgt cattttcatt ttatacaaca
     1081 gcaattgctc atagagcagg agctgaaatg gctccagaga atactttggc agcaatagaa
     1141 gaagcttcac atgctaaagc tgattatgca gaaatagatg ttcaagaaac taaagatgga
     1201 gaacttattg tacttcatga ttcaaacttt aagagaacta caggagtaga taaaaatgtt
     1261 tgggatgtaa attataatga agtaaagaca tatgatgcgg gaagctttta ttattatgga
     1321 aaaggttatt atgatgaaaa gtttgttggg gaaaagatac caacactcaa agaaatgata
     1381 aaatattcta aaggtaaggt gaaattatta atagaaataa aacttaatgg acatgaaaag
     1441 ggagacgtag taaaaaaagt tgttcagtta attaaagaaa ataattttga aaatcaatgt
     1501 atagttgcat ctatggataa aactatatta caaaaagtaa aaaaactgga tgagaattta
     1561 ctgacatgct attttatggc aattgcatat ggtgattttt caaagttaaa ttatgttgat
     1621 atatatggaa ttgaatcaac ttttgttaat aaaacagtag tagaaaagat tcataaaatg
     1681 aacaaaaaaa tcttcgtttg gactgttaat agtgacagtt taattgagaa aatgcttgac
     1741 ctaaatgtag atagtattat tacagataat ccatacctta tagagagtgc aatttattgg
     1801 aagaaaaatg gatttattag tcaagtgtca gattatttat tttaaatatt ctataattgt
     1861 attatccagt aaaagagata ttattaaaat caataatatc tctttttaac ataaataagg
     1921 ttgttaaatt aaggctattc ttataaaaat tgtgtttatc agatataaat aaggaataaa
     1981 agtaaaaaaa ttgctatgac attattacaa ttaaaagagt tttaatatga tagagaggta
     2041 gattgtcaac tgtatattta ataaatttta ttatttatta gattttatat aagtaaaata
     2101 tatagatata taaatcttat gctagaatat atatgaaaaa caatatagat ttggagggtt
     2161 aaaagcatga cagagcgaga aaaaatgttg gcaggagaac tttacgattg tggtgatatt
     2221 gagttgttaa ctcaatggca taaagcaaaa gacctagtaa gagattataa ccaaacagat
     2281 tccttggatt tggaaaaaaa agaaaaaata ttaaatgagt tacttggtgg taagggtaaa
     2341 aacttatgga ttactgcacc gtattatgta gattatggaa ataatattta ttttggaaat
     2401 aattgtgaag tcaatatgaa ttgtacgttt ttagatgata ataaaattat cattggggat
     2461 aatgcactaa tcgcaccaaa cgtacaaata tatactgcat ttcatccaac taatgctggt
     2521 gatagatttg gtaatgccaa agaagatggt tcatttgaat tttgtaaaac tcaaacagct
     2581 ccagttacta ttggagataa tgtttggatt ggcgggggtg ctattatcat gccaggtgtt
     2641 actattggag ataatgtagt tataggtgca ggaagtattg ttacaaaaga tattccaagt
     2701 aatatgattg catacggaaa tccatgccgt attattcgag aaaataaata aagttaaatt
     2761 ttcttgcaaa atctcaaaaa acacctttct tactttatac atagggtatt ttctaatact
     2821 ttcacatcca tattcatttg ttaaattttt gtggaatgta gtttttatca cttctatctt
     2881 acatttccac cattttttta taaaagtcat tcctttatag atttatttat aatagtatat
     2941 attctatttg atgtttgaat aagcacttat ttttaagtaa aatactaact tctaggttag
     3001 tattttacta tagt
//
LOCUS       DAEPKC010000189         2958 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.192, whole genome shotgun sequence.
ACCESSION   DAEPKC010000189 DAEPKC010000000
VERSION     DAEPKC010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2958)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2958)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2958
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.192"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            81..761
                     /locus_tag="KR294_003674"
     CDS             81..761
                     /locus_tag="KR294_003674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0241714.1"
                     /translation="MQIDVLIIDGDKNSSQELKNFLEGKGINVYLAYNCKDAIIKIFS
                     KKFDLIFLEIILVDGDGWDFCKKVRSITTCPIIHITYINENQSILNALNSGGDDYLIK
                     PLNLEILYAKVKAILRRRDLFLNNNKNNIKLEDYNRASGVIKLENKMIKLTPTENRLL
                     NYFIENAEKTLTIKEIYEHVWMNEYLDDNYSVVVAVSGLRKKIEKDYKNPQKIITIRE
                     VGYYFNKI"
     gene            1208..1492
                     /locus_tag="KR294_003675"
     CDS             1208..1492
                     /locus_tag="KR294_003675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241715.1"
                     /translation="MLVYNKSFYPNDIFPRLDFSKIKKQLKLIDNDLSDFGSICIIEK
                     EHYTISVNSIGEINVYYDLEYENKVYRIVYEIEKLFKSQVGRFSISTYRN"
     gene            complement(2263..2478)
                     /locus_tag="KR294_003676"
     CDS             complement(2263..2478)
                     /locus_tag="KR294_003676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0241716.1"
                     /translation="MAIVVNLDVMMAKRKISLKELAEKIDITNANLSILKTGKAKAIR
                     FTTLNEICKALDCQPGDILEYVEDEND"
     gene            complement(2489..2956)
                     /locus_tag="KR294_003677"
     CDS             complement(2489..2956)
                     /locus_tag="KR294_003677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HBH0241717.1"
                     /translation="MITKFFSNILSVFLYFLLSLLGVAGIIFLCMIPMFLYDFSSDKV
                     IALIARILYFSDYFIVILFLIFIINSTKYSPFVLENVKRFKVMGFCLLINTIIECING
                     YNLNTNNIRIFGTDSGGISPLMVISFIFALMCFVIAETFDKAIKIKEDNDLTI"
BASE COUNT         1240 a          265 c          398 g         1055 t
ORIGIN      
        1 aaaaaatgct attagaaaat gtactaaaaa tatttttcca attctttata gaaaaataat
       61 gatatttagg agagattgta atgcaaattg atgtattgat aattgatgga gataagaata
      121 gttctcaaga gctgaaaaat tttttagaag gaaaggggat aaatgtctat ttagcatata
      181 attgtaaaga tgctattata aaaatattta gcaagaaatt tgacttaata tttttagaga
      241 taattttagt tgatggtgat ggttgggatt tttgtaaaaa agttagaagt ataactactt
      301 gcccaattat tcatataact tatataaatg aaaatcaaag tattttaaat gctttaaatt
      361 ctggaggaga tgattattta ataaagcctt taaatttaga aatattatat gcgaaagtga
      421 aagctatttt aagaagaaga gatttatttt taaataataa taaaaataat ataaaactag
      481 aagattataa tagagctagt ggagtaataa agttagaaaa taaaatgata aagttaactc
      541 caacagaaaa tagattatta aattacttta tagagaatgc tgaaaagact ctaactatta
      601 aggagatata tgaacatgta tggatgaatg agtatttaga tgataattat agtgtagtgg
      661 ttgctgtgag tggattaaga aagaaaatag agaaagatta taaaaatcct caaaaaatta
      721 taacgataag agaagtaggg tattacttta acaagatata aagctttata aacagaatga
      781 atgataaggc atagataata tgttagtata ttacaagagt ttttgttcta acgatatatt
      841 tgtaaaatta gatttaattt acttaattaa attatagcag tagaataaat ataaaaaatg
      901 tctgaaatat tatagacatc agtaaaatat ataaaactat aatataagtc gtaataataa
      961 aacaaatgaa tattaattaa taaaaagata gtagctattt ttatatagct attatttttt
     1021 tattgttgtg gatgaaaata tacttatatt ttactaatat acatttaaaa attacaattt
     1081 aaagcattaa aaaataaatt tgtattttgt tttatataaa gtaatttgaa aaatatggaa
     1141 aaattgatta gtacattatt aattagggta taaaatggtg taaatagaat gataaggggt
     1201 ggatgaaatg cttgtatata ataaaagttt ttatcctaat gacatatttc caagattaga
     1261 tttttcaaaa ataaaaaaac agttaaaatt gatagataat gacctgtcag attttggaag
     1321 catatgtata atagaaaaag aacattatac gataagtgta aacagtatag gtgaaataaa
     1381 tgtgtactat gatttagagt acgaaaataa ggtgtataga atagtttatg agattgaaaa
     1441 gttatttaaa tctcaagttg gaaggtttag catatctaca tacagaaatt gataattaaa
     1501 aaagtagaaa ttaaaaaact taatactaaa gatatagata aatatatgag gtaacagcta
     1561 gagagagttg ttaccctttt taaatactaa gtatatatta ttcttattaa ttttttgtaa
     1621 attcactaaa agaccttttt atagaatatt attttctttt tttattaaat aggtaaatca
     1681 gtaaaaatgc aattccagtt ccaattatta ttccaatgat attttctata attaattttt
     1741 ttaatataaa agtaaataat aaaaatgcta tacataaacc taaaatatat cctttaaaat
     1801 aggttgaaag ttttcttttc atataatcac caacttgtat cagatttagt ttacttaatt
     1861 agagtataac agtgttgtaa cttcaaagag tatctaaaag attacaaatg ttagataaaa
     1921 tcatcaataa tgtaatttat aacacatagc tataagctat gcaataatat aaatggaggt
     1981 ataagtaaat gaaaaagttc catgttttgc taacagttta aataaatatt atgtagaaaa
     2041 gaatgtatat aggaatctgt ggtaaaatta tcaatttaaa agtattattt agtgtgatac
     2101 agttcttata ggtaatggat aacaaataga taaaggaaca gtttctttct tagaacatat
     2161 tttgttatga ctttaaacaa agttaatatt aatgtcaata atatagtaaa agaataaaaa
     2221 tcatatagta taataaaaaa gagtgtttct aaacactctt ttttaatcat tttcatcttc
     2281 tacatattca agtatatcac ctggctgaca gtctaaagct ttgcaaattt cgtttagagt
     2341 ggtaaatcta atagcttttg cttttccagt ttttaaaatt gataaatttg catttgtaat
     2401 atctattttt tctgccaatt ctttaagtga tatttttctt tttgccatca ttacatctag
     2461 gttaactact attgccataa catcacctct atatcgttaa atcattatct tcttttattt
     2521 ttatagcttt atcaaatgtt tctgcaatta caaagcacat tagtgcaaat ataaaagaga
     2581 taaccataag tggtgagata ccgccactat cagttccaaa aattcttata ttattagtat
     2641 ttaaattata accattgata cattcaatta tagtgtttat caataaacaa aatcccatta
     2701 ctttaaacct ttttacattt tcaagtacga atggggaata cttagtacta ttaattataa
     2761 atatcaagaa taagatgact ataaagtagt cagaaaaata tagtattctt gcaattaaag
     2821 caattacttt gtcagaacta aaatcatata aaaacatagg tatcatacat aagaatatta
     2881 taccagcaac tcctaaaagt gataatagaa aatatagaaa tactgataat atattactaa
     2941 aaaattttgt aatcataa
//
LOCUS       DAEPKC010000190         2907 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.193, whole genome shotgun sequence.
ACCESSION   DAEPKC010000190 DAEPKC010000000
VERSION     DAEPKC010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2907)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2907)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2907
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.193"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     repeat_region   1..1015
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=1..26
                     /rpt_unit_seq="tacataccacatagttaatataaaac"
     gene            1662..>2907
                     /locus_tag="KR294_003678"
     CDS             1662..>2907
                     /locus_tag="KR294_003678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HBH0241718.1"
                     /translation="MLKVLKGNIIFTKTSETFTVFENSYIILEKGKVKGIFKEIPKEY
                     KNLKVVDYTDKLIIPGMNDLHAHASQFKNLGMAMDKELLPWLETYTFPEESNYKDIEY
                     ATKMYKKFVKELWKSGTTRIAVFATVHKEASMKLMDIFKEVGLGAYVGKVNMNMNCPD
                     TLLENTQDSITDTEEIINKYSDTDSIVKPIITPRFIPSCTSELLKGLGDLCLKYNIPI
                     QSHLSENYDEIEWVRSLEPESKFYGDAYNRYNLFGQTPTLMAHCVHCSQDEIDLMREN
                     NVMAVHCPASNFNVGSGAMPIRKLIDNNIRLALGSDISGGHTLSIFKAMVSAIQLSKL
                     YWVNSGKKYNFLSLSEAFYIATKSGGSFFGKVGSFEEGYDFDALIIDDSNLNHDNYSI
                     LERLERFIYVGDDRNIIHRYVCG"
BASE COUNT         1141 a          397 c          378 g          991 t
ORIGIN      
        1 tacataccac atagttaata taaaacaact tctcatattc cagataattg ttattttacg
       61 aaatttacat accacatagt taatataaaa cctgtagatt tgcctgtttc gatattgctc
      121 atgtgtgaat ttacatacca catagttaat ataaaactct cttgtttctt ctgttaattt
      181 tattatacct tcattattta cataccacat agttaatata aaacgcgtta tattgttgta
      241 taaaaccgat taaagttcaa tttacatacc acatagttaa tataaaactt gcaacatatt
      301 gttttatcgt tgctgggtct ttaaaaccat ttacatacca catagttaat ataaaactaa
      361 gcgatattag agagcgcaag gcatagcgga gcaaatttac ataccacata gttaatataa
      421 aactttaatt ttaaccaccc cctttcacta ataaaaaaag atttacatac cacatagtta
      481 atataaaaca agacgctata caagaggtaa tttgaaagca atctaattta cataccacat
      541 agttaatata aaacgttgca tatgtatgtc taagagcatg aaatttaatt ttatttacat
      601 accacatagt taatataaaa cttctattaa gtgtaagcaa aacgcttgga atatgaaatt
      661 tacataccac atagttaata taaaacttat acacaaatac aacttgaaga agcgctaaag
      721 agatttacat accacatagt taatataaaa cctaatgagt acatagataa acgtacagga
      781 gaggttaatt tacataccac atagttaata taaaacgttg ataattttcg tttgtatact
      841 ttttataatt taaaatttac ataccacata gttaatataa aacataaaga tttagaaaaa
      901 gaaaaagtta aaattttgga atttacatac cacatagtta atataaaact tttcctgtta
      961 agttgatgtt tgcaacttta actgctattt acataccaca tagttaatat aaaaccccaa
     1021 aataaactaa gtattttcag tacttacaca catacaactc tctcaaattt gcagtgaacc
     1081 atgagtagtg caattgataa catttatcac acaccctcaa tcccttacat tgcaactgtt
     1141 aaaccctact ttatcaaaaa tatcgctcac tgcaaaattt atatattttt attatatcat
     1201 aaaattcaaa ctataaaatt aaaatggaat aatttatcaa tttaagaaca cctacatatt
     1261 tgtaaatact tactatatta tctattctaa taattcttct tctagctgga actaatataa
     1321 aaatcatctc tgaaagatta ggacatacta atataaaaat aactatgaat agatattttc
     1381 ttgttttaaa cgatatggat aaaaaagctt ctgaaaatat aatcaaagtt ctctttaaat
     1441 aacattccat tttatgtaag taggcattat atttttctta aatgtcactt aaatgtcagt
     1501 tatatataat aatagtaaac aactgtattt cactaatatt tgctattatc taatagtatt
     1561 tatagtttag atttgatata atacatgtgg taaaattttg atttgtaaaa caaaatttta
     1621 cctacatata ttaaaacaaa tttaaaacta aggagaccta tatgttaaaa gtattaaaag
     1681 gaaatataat ttttacaaaa acttcagaaa ctttcacagt atttgaaaat agttatatta
     1741 tactggaaaa aggtaaagta aagggaatat ttaaagagat acctaaggaa tacaaaaacc
     1801 taaaagtagt agattacact gataagctta taatacctgg tatgaatgac ctccatgccc
     1861 atgcctctca atttaaaaat cttggaatgg ctatggataa agagcttttg ccatggcttg
     1921 aaacttatac atttccagaa gaatcaaatt ataaagatat agaatatgca acaaaaatgt
     1981 ataaaaaatt tgtaaaagaa ctttggaaat ctggaactac aagaatagca gtgtttgcaa
     2041 cagtacataa agaagcctct atgaaactta tggatatatt caaagaagtt ggtcttggag
     2101 catacgttgg taaagtaaat atgaatatga attgccctga tactttatta gaaaacactc
     2161 aggattctat tactgataca gaagaaatta taaataagta tagtgataca gattctattg
     2221 taaaaccaat aataacacct agatttatac caagctgtac aagtgaactt ttaaaaggtt
     2281 taggagattt atgtttaaaa tataatattc ctattcaatc acacttatct gaaaattatg
     2341 atgagattga atgggttaga agtctagaac ctgaatctaa attctatgga gatgcatata
     2401 atagatataa tttatttggt caaactccta ctttaatggc tcattgtgtt cattgttctc
     2461 aggatgaaat agatttaatg agagaaaata atgttatggc agttcactgt ccagcttcta
     2521 actttaatgt tggtagtggt gctatgccta tcagaaaatt aatcgataat aatattagat
     2581 tagcacttgg atcagatata agcggtggac atacattgtc aatatttaaa gcaatggtat
     2641 ctgcaataca attatctaaa ttatattggg ttaattctgg taagaagtat aatttcttat
     2701 ctttatctga ggctttttat attgcaacca aaagtggtgg aagtttcttt ggaaaagttg
     2761 gtagctttga agaaggttat gattttgatg cattgattat tgatgattca aatttaaatc
     2821 atgacaatta ttctatactt gaaagacttg aaagatttat ctatgttggt gatgatagaa
     2881 atatcattca tagatatgta tgtggaa
//
LOCUS       DAEPKC010000191         2868 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.194, whole genome shotgun sequence.
ACCESSION   DAEPKC010000191 DAEPKC010000000
VERSION     DAEPKC010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2868)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2868)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2868
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.194"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(<1..704)
                     /locus_tag="KR294_003679"
     CDS             complement(<1..704)
                     /locus_tag="KR294_003679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBH0241719.1"
                     /translation="MFAEERIQAILNILKKEGRVTVKELSSKFNVTEDCIRKDLKNIE
                     KISSIRRIYGGAVLARETLENQDTKDRKEINIPTKKIIAEKAFNLIEDRETIFLDIST
                     INILLAKLLAESNKKVTLVTNMLDILNVVTSKPNNLNIISTGGLLNLSLDGFVGTPTI
                     EFISKYKFDKTFMGSCGVDVFNSSLTTFEIEDGLTKKAIINSSKKVFIVMEDKKFKFD
                     GNFKFAHLEDISSIIT"
     gene            978..1652
                     /gene="fsa"
                     /locus_tag="KR294_003680"
     CDS             978..1652
                     /gene="fsa"
                     /locus_tag="KR294_003680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HBH0241720.1"
                     /translation="MQLILDTGNVEEIKELCTCLPIDGVTTNPSIVSKEKKNFKQLIN
                     EIGEIIGEDMPIHAQVLSTKYEEILEEALYISSLRKNIYVKIPVTQDGLRAIKDLHRK
                     GVKITATAIFTAHQGFLAAKAGANYIAPYVNRLDNISGDGVAMVSELIKIIDTYKMDT
                     KVLAASFKNAQQVIELMQHGVHSVTVPYDICKSMMNHPLTDWSVDKFIEDWENTFGKG
                     SKTNNI"
     gene            complement(1774..>2868)
                     /locus_tag="KR294_003681"
     CDS             complement(1774..>2868)
                     /locus_tag="KR294_003681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anion permease"
                     /protein_id="HBH0241721.1"
                     /translation="AKIISEKLILNTVNTPKKMILLSYILGILLIFFIPQPFPRVILV
                     SAFYKEFLKEQQITEDSKSILLFSIFTASTFTSMFFVNGDTLLNYVVLELGNCNINWG
                     QWAFYMSVPTIITCFITYFLFTFVFKKELHSIKFISNENLEGNKLHFSYSNLKKEFNL
                     LNKEQKHVFLCLGIMFFMFLTQFIHNINTLIIMSICVLLLLLRKIVGFSTLKEINWKV
                     LIFFIAAFSIGGVLKYSGVVDIMGNYLIKFIPNSSEIISILFLITLTIILNICLGSAV
                     TTSSVVIPLLGSLHILKENSVTLCLFVYIIVSIQYILPFHHATIMVGHGENLYNSKVI
                     FKYGLTLIPLTYFIIICITFPWWKFIGLEI"
BASE COUNT         1110 a          360 c          380 g         1018 t
ORIGIN      
        1 tctgtaatta tagaactaat atcttctaaa tgagcaaact tgaaatttcc atcaaattta
       61 aactttttat cttccataac tataaatact tttttacttg aatttattat agccttcttc
      121 gtaagaccat cttcaatttc aaaagttgta agtgaagagt tgaatacatc tactccacaa
      181 cttcccataa aagtcttatc aaacttatat ttcgatataa actctatagt tggagtaccg
      241 acaaaaccgt ctaaactgag atttaataaa cctccagtgg aaattatatt taaattattt
      301 ggttttgaag taactacatt tagtatatcc agcatatttg taacaagtgt tactttttta
      361 ttactttcag ctaacaactt cgcaagcaag atgttaattg tagagatatc taaaaatata
      421 gtttctctat cttcaattaa attaaatgct ttttctgcta ttattttctt tgttggaata
      481 ttaatttctt ttctgtcttt tgtatcctga ttctctagtg tttctctagc tagtacagct
      541 cctccataaa ttcttcttat tgaagaaatc ttttctatat tttttaaatc ttttcttata
      601 caatcttctg taacattaaa tttagaactg agctctttga cagtaactct accttctttt
      661 tttaggatat ttaatatagc ttggattctt tcttctgcaa acattttcta cctcttttcg
      721 caatatagta ttatagtaaa tattataaga taaaatacaa tatatcaact attttaacat
      781 gaaatacaaa attaatttaa tataaaaagt atgttttttc taactatata tttagaattt
      841 agtaaataaa aaaattataa aactaagaag gaaaagtaaa acaataataa aaaataaaaa
      901 acaataagca aaatgttgaa aataatacca aatcaatata taataagaat aaagaaagat
      961 taaaggggga tattttaatg caactaatct tagatacagg taatgtggag gagattaagg
     1021 agttatgtac ttgtttacca atagatggtg taactacaaa tccaagtatt gtttcaaaag
     1081 aaaaaaagaa ttttaagcaa cttataaatg aaattggtga gattataggt gaggatatgc
     1141 ctatacatgc tcaagtgtta agtacaaagt atgaagaaat attagaagaa gcattatata
     1201 taagtagttt gagaaaaaat atatatgtaa aaatacctgt aacacaagat ggtttaagag
     1261 ctataaaaga ccttcataga aaaggtgtaa aaataactgc tactgcaata ttcactgctc
     1321 atcaaggttt tttagctgca aaggctggag caaattatat tgcaccttat gtaaataggc
     1381 ttgataatat atctggtgat ggagtagcta tggtttcaga acttataaaa ataatagata
     1441 cttataaaat ggatacaaaa gtacttgcag ccagttttaa aaatgcacaa caagttatag
     1501 aattaatgca acatggggtg catagtgtta cagtaccata tgatatttgt aaatctatga
     1561 tgaatcatcc attaactgat tggagtgtag ataagtttat agaggattgg gagaatactt
     1621 ttggaaaagg aagtaaaaca aataatattt agtattatgg taaaagagta gttttgtcca
     1681 attttacaag aacttatata aaaagatgaa aatatgaatt ttctttttaa taatttcgtt
     1741 attatcttaa gttaattcat attttcatct tttttagatt tctagtccta taaatttcca
     1801 ccaagggaat gttatacata ttattataaa gtaggttaaa ggaatcaaag ttaaaccgta
     1861 tttgaaaata accttgctat tatacagatt ttcaccatga ccaaccatta ttgtagcatg
     1921 atgaaatggt aatatgtact gtatgcttac tataatgtag acaaatagac ataaagtaac
     1981 actattttcc tttagtatat gtaaacttcc aagtaatggt attactacag atgatgtagt
     2041 gacagcactt ccaagacata tattcaagat tattgtgaga gttatcaaaa acaatattga
     2101 aataatttct gaagagtttg gtataaactt tatcaaataa tttcccatta tatctacaac
     2161 tccagagtac tttaacactc ctccaattga aaatgctgct ataaaaaaaa taaggacctt
     2221 ccaatttatt tcttttaaag tactaaatcc aactattttt cttagtaata aaagaagtac
     2281 acaaattgac attataatta atgtgtttat gttatgtatg aactgagtta aaaacataaa
     2341 aaacattatt cctaggcata aaaatacgtg tttttgttct ttgtttagca aattaaattc
     2401 tttttttaaa ttagaatatg aaaaatgaag tttattaccc tcaagatttt cattagaaat
     2461 aaattttatt gaatgcaatt cttttttaaa gacaaaggta aataaaaaat aagttataaa
     2521 acaagtaatt atagttggaa cagacatata aaaagcccat tgaccccaat ttatattaca
     2581 atttccaagt tctagtacaa cataatttag aagagtgtct ccatttacaa aaaacattga
     2641 tgtaaaggta gatgctgtaa atatactaaa taaaagtata gattttgaat cttcagttat
     2701 ctgttgttct tttaaaaact ccttgtaaaa agcagataca agaataaccc ttggaaatgg
     2761 ttgtgggata aaaaatatta aaagtatacc taaaatatac gataaaagaa tcattttttt
     2821 aggggtattt acagtattta aaattaactt ctcagaaata atttttgc
//
LOCUS       DAEPKC010000192         2823 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.195, whole genome shotgun sequence.
ACCESSION   DAEPKC010000192 DAEPKC010000000
VERSION     DAEPKC010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2823)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2823)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2823
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.195"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            397..771
                     /locus_tag="KR294_003682"
     CDS             397..771
                     /locus_tag="KR294_003682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH0241722.1"
                     /translation="MKVLISNTSDKPLYQQIKEQIKEAIFTEELKEGDAMPSIRNFAN
                     DLKVSILTIRRVYEELENEGFLTRQVGIGTFISTGNLEILRDSKRRIVEQKMADMIKD
                     AKALGITQIELQEMMDILYEED"
     gene            773..1630
                     /locus_tag="KR294_003683"
     CDS             773..1630
                     /locus_tag="KR294_003683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0241723.1"
                     /translation="MENILEVYNLNKTYTDFSLSNISFALPEDCITGFIGVNGAGKTT
                     TIRSILDVVKRDSGKIKIFGKDFDGNEKELKNRIGVVFDDSYFYEELSMAEMKSIIAP
                     SYDNWCEEDYQQNMKRFNLNPKQKIDTLSKGMKMKFALALALSHKAEFLIMDEPTSGL
                     DPLIRSQILDILTGYMKKCGRGVFFSTHITSDLDKIADMIVMIDNGRIILEREKDTLL
                     DEHRKVKGDIQFLNDETKKLFLNLEITGYGFIGITSKINEVQKNMPDILIERPTIEDI
                     MLAYIERRE"
     gene            1633..2271
                     /locus_tag="KR294_003684"
     CDS             1633..2271
                     /locus_tag="KR294_003684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 transporter permease"
                     /protein_id="HBH0241724.1"
                     /translation="MLIHLVKKDILIVKKYVLLILFIAIGIPLFILWRLPPFAQILGF
                     VLSIIFSEFMLCQYLLLKESQYSKASVLLCSTPYPRRGLVQSKYVLFAMVFIYCTLVY
                     WIENLLIPQIGTFDLTYILIVLLISSIIYGVYMPIQYKLGYETTKFFFVMIIMASSFV
                     LPLTIAHSNFEIPFIYQYPSMIVNIVLFLLSLIILLASMFISIKIFSNKELV"
BASE COUNT         1026 a          318 c          443 g         1036 t
ORIGIN      
        1 ctttcctcta tccaaattct tataaattca tcccatttat tactatttat ttattattat
       61 ctaaattttt tagtatgttt gtaattagaa atggatttat tcctttatgt tttttataaa
      121 tagtttataa cttaatttat cattaaacaa atcattcata caggattact ttttctttta
      181 tatattcaat tcttactttt aataaatatt taatacatcc tatcttatgt agttttaaaa
      241 agtgtttatg gctattaaca atctctaata tttcattcat atttattttg tcatagtaat
      301 attttacatc ttttatattg acaaaaaagt gctctaagtg tatagtgtgt atatgataac
      361 atcacactga aagtgataaa aagggggtga taaaaaatga aagtgctcat ttctaacaca
      421 tcagataagc cattatacca acaaattaaa gagcaaatta aagaagcaat atttactgaa
      481 gaactgaaag aaggggatgc aatgccatcc ataagaaatt ttgctaatga tttaaaagtt
      541 agtattttga ctattagacg agtgtatgaa gaacttgaaa atgaaggctt tcttacacgc
      601 caagttggaa taggaacatt tatttcaact ggaaatttag aaatactaag agactcaaag
      661 agacgtatag ttgaacaaaa aatggcagat atgattaaag atgcaaaagc actaggaatt
      721 acacagatag agttacaaga aatgatggat attctatatg aggaggatta atatggaaaa
      781 tattttagaa gtttataact taaataagac ttataccgat ttttcattat ctaatataag
      841 ctttgcatta ccagaagatt gtataaccgg atttataggt gttaatggag caggaaaaac
      901 aacaacaatc cgttcgatat tggatgtcgt aaagcgtgat agtggaaaaa taaaaatctt
      961 tggtaaagat ttcgatggaa atgagaagga attaaaaaat cgaattggag ttgtctttga
     1021 tgattcatat ttctatgagg agttgtcaat ggcagaaatg aaaagtatta ttgcaccttc
     1081 atatgataat tggtgtgaag aagattatca acaaaatatg aagcgtttta atcttaaccc
     1141 aaaacaaaag attgatacac tttcaaaagg aatgaaaatg aaatttgctt tagcattagc
     1201 attatcgcat aaagctgagt ttttaattat ggatgagcct acaagtggtt tagacccact
     1261 aatccgtagt cagatacttg acatactaac aggatatatg aagaaatgtg gtcgtggtgt
     1321 tttcttttcc actcatataa catctgattt agacaaaata gcagatatga ttgttatgat
     1381 tgacaatgga cgtattatat tagagcgtga aaaagatact ctattggacg aacatagaaa
     1441 agtaaaaggg gatattcaat ttctaaatga tgaaaccaaa aaattatttt taaatttaga
     1501 aattacaggt tatggtttta tagggattac ctcaaaaatt aatgaagtgc aaaaaaatat
     1561 gccagatatt ttaatagagc gtcctacaat tgaagatatt atgcttgcat atattgaaag
     1621 gagagagtaa ttatgttgat tcatttagtt aaaaaagata ttctgattgt aaaaaaatat
     1681 gtattgttga tattatttat tgcaatagga atcccattat ttatattatg gcgtttacct
     1741 ccatttgcac aaatattggg atttgtacta tcaattatat tttcagaatt tatgctgtgt
     1801 cagtatctat tattaaagga gagtcaatat tcaaaagcat ctgtattact ttgttcaact
     1861 ccttatccta gacgtggctt agttcaatct aagtatgttt tatttgcaat ggtatttatc
     1921 tattgtacat tagtttactg gattgaaaat ttacttattc cacaaatagg aacttttgac
     1981 ttgacatata ttttgattgt tttattaata agttctatta tttatggagt ttatatgcct
     2041 attcaataca aattaggata tgaaacaaca aaattctttt tcgtgatgat aatcatggct
     2101 tcatcatttg tattaccatt aactatagct cacagcaatt ttgaaattcc atttatatat
     2161 cagtatccat ccatgatagt gaatattgta ttgttccttt taagtttaat tatactgtta
     2221 gcttcaatgt ttatttctat taaaattttt agtaataagg agcttgtata aggtaagggg
     2281 gacttttata tgccacattt accagattgg gctgttttac tttgtatctt acttccaata
     2341 gtatataaag cttgtcagat atttaaaagt aaaaaataga gtatatattt atattgccat
     2401 ttttattgag tgaagttaga tggtatgaaa aggttacttg aaaataaagt tacttggtgt
     2461 gggagagtaa catcataata ttatagatta tatgtttctt gtgaatcaat ttgtattttt
     2521 taatagggaa tatccagtaa ttttgttttc cattgattat ttttcaatta tgagtatgat
     2581 tgtgtgtatt gtataccatc ttttaaggtg tttttaaaaa attatatcgt caaaatataa
     2641 atctaaggaa tcctataaat aaagcttttt aattttagaa aactaataaa aagtaggacg
     2701 ttaataaaaa gaagctgtct caaaatagag ataagcttct ttttcattgc tgaaatgacg
     2761 aaaatataat tgatttaata taaaaaagag tgctttatga actatttatt ttgaacagta
     2821 gat
//
LOCUS       DAEPKC010000193         2801 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.196, whole genome shotgun sequence.
ACCESSION   DAEPKC010000193 DAEPKC010000000
VERSION     DAEPKC010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2801)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2801)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2801
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.196"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(200..343)
                     /locus_tag="KR294_003685"
     CDS             complement(200..343)
                     /locus_tag="KR294_003685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241725.1"
                     /translation="MSEFLLGVLASLTASFITYIISRKVKSHSGRSDFELDVKIKFNK
                     KRH"
     gene            601..789
                     /locus_tag="KR294_003686"
     CDS             601..789
                     /locus_tag="KR294_003686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241726.1"
                     /translation="MTKTILCDYCNKGINKDDNKYITFHKKSHMKTNICINCALNLID
                     KDKLNENIINNQHDYSKK"
     gene            1490..2011
                     /locus_tag="KR294_003687"
     CDS             1490..2011
                     /locus_tag="KR294_003687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HBH0241727.1"
                     /translation="MDFKIRELINDITQDIIQTYKIQIPIVNINQVVDALGGKVIEDS
                     SLSGYSDGFIRKVDDSFEIVVSPYQPDTRKNFTIAHELGHLFLHMGYGIDDELWNSQD
                     GNQYFRSGNTNKEYQSNEFAAALLMPKHEYKRIMDENTVGNKVDTSKIAEYFNVSSYA
                     ASNRGKWLGYLQW"
     gene            1987..>2801
                     /locus_tag="KR294_003688"
     CDS             1987..>2801
                     /locus_tag="KR294_003688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241728.1"
                     /translation="MVRIFTMVDDKEYKTQNVNNVHNSAKNENAFNLKKYKEKLQENI
                     NTDIYEKEKEPNHPEVILFFSFDIANSSLYKNINYSGWAKVLSHIIRKLQYRVYENLK
                     AQLWRVLGDEVIFIIVLKNYDEIYKYIDIIFDILTSTAKDIKSGNIFSTLEGFSESEK
                     YLMKLQNIISLKGAAWIAIVSRNPNFNALENNEQYENISAMYDLSNNYKIFEFLGNDI
                     DAGFRISKQTCPERLVLSFELAYILSRKTDILSKLHIITYKKLKGIWKDKLYP"
BASE COUNT         1098 a          312 c          368 g         1023 t
ORIGIN      
        1 catatactct ttttgttttt gtgaaagttt tttaggtggc taataatata tatacttaga
       61 gataaaataa aatatatttc taatattcat agttttattt tttctcaaaa tgcgatataa
      121 taaagatgta aattcgtatc aaaaacaaaa aaagaaacta caatctatta gcctagagtg
      181 aagtttcatt aactaaatat taatgtcgtt ttttattaaa cttgattttt acatcaagct
      241 caaagtcact cctgccagag tggcttttta cttttctgga aataatatat gtaataaagc
      301 tagctgttaa actagctaac actcctagta aaaattcgct catttctcca cctccttcct
      361 tttaagggat ggaatgtaga aaatgaagct ccactcttag attgtagttc cacaagatta
      421 ttcttgcatt ttaattataa cataatttta caattatcaa atatctattc tccatttttt
      481 ttatttatac aatatattct atattgcaat aaaaaacatt gttttaaata tatatacata
      541 ggtatatact aaatatgtta aacttaatta tggaaaatat aaaatgaaag gaataaaaat
      601 atgactaaga ctatattatg tgattactgt aataaaggaa taaataaaga tgataataag
      661 tatattactt ttcataagaa aagtcatatg aaaactaaca tttgtattaa ttgtgcatta
      721 aatttgatag ataaagataa attaaatgaa aatattataa ataatcaaca tgattattca
      781 aagaaatgaa aaagcactct ccataatgaa gaatgctcta tataataatg tttgacttag
      841 taaagatgtg ttggggttac atatttactt ttttattata tcatataact ttgtgtatga
      901 aaaagaattt aaatcaattt taggtgtgtt gagtaatgtt cttgatagtt tatatgttga
      961 tgaatttcaa aaaaataagc actcttataa aaagagtact tttggtatat attcaagcat
     1021 ttatctaata caattatagc atgtcttatg ttttagtatg ataattttcg ttcgttttat
     1081 tattacaact tctactatag ttttcatact ttaacatcaa ctaaatgaat ttaattaaga
     1141 ttactagtta atcgtttttt ggttctttca tattctgaaa tctaaaattt tattatttgt
     1201 ttattgttat tatttaacac atgttggtat ttcaacgatt tatcttattg ttaatattct
     1261 tattgcttcc aaagtatatc taattatttt taagataatt tactaatttt tattttttca
     1321 aacatacatt cgacaaaaaa cagtttttat atggtataat tatattgtat aatacaaaag
     1381 gttaatgaaa ataattaata ttaaatgtac caaaaaaaat agtttttgat ataatgaata
     1441 ttataataaa taattattta aataaaatat tatataagga tgtgatttta tggatttcaa
     1501 aatcagagag ctaattaatg atataaccca agatattatc caaacataca aaatccaaat
     1561 tccaatagta aatataaatc aagttgttga tgctttagga ggcaaggtaa tagaagatag
     1621 ttctttaagt ggatactctg atggatttat tagaaaagtt gatgattcat ttgaaatagt
     1681 ggtatctcct tatcaaccag ataccagaaa gaattttacc attgctcatg aacttggaca
     1741 tttattttta cacatgggtt atggcattga tgatgaacta tggaatagtc aagatggaaa
     1801 tcagtatttt agaagtggca ataccaataa ggagtatcaa tccaatgaat ttgcagcagc
     1861 cttgttgatg cctaaacatg aatataaaag aattatggat gaaaacacag taggtaataa
     1921 ggtcgacact tcaaaaattg cagaatactt taatgtttcc tcttatgcag catctaatag
     1981 agggaaatgg ttaggatatt tacaatggta gatgataaag aatataaaac tcaaaatgta
     2041 aataatgttc ataattcagc taaaaacgaa aacgctttta atcttaaaaa gtataaggaa
     2101 aaacttcaag aaaatattaa tactgatatt tatgaaaaag aaaaagaacc taatcatcca
     2161 gaagtgattt tgttcttttc ttttgatata gctaattcat cattatataa aaatataaat
     2221 tatagcggat gggctaaggt attatcacat ataattcgta agttacaata tagagtttat
     2281 gaaaacctta aagcacaact ttggagagtt cttggtgatg aggtaatttt cattatcgta
     2341 ctaaaaaatt atgatgaaat ttataaatac atagatataa tctttgatat tttaacaagc
     2401 actgctaaag atataaaaag tggtaatata ttctctacac tagaaggatt ttctgaatct
     2461 gaaaaatact taatgaaact tcaaaatatt atttcattaa aaggagcggc ctggattgct
     2521 atagtatcaa gaaatcctaa ttttaatgct ttagaaaata atgaacaata tgaaaatatt
     2581 tctgctatgt acgatttatc caataattat aaaatatttg agttcttagg aaatgatatt
     2641 gatgctggtt tcagaatatc aaagcaaaca tgcccagaaa gacttgttct tagttttgaa
     2701 ctagcttata tattatcaag aaaaactgat attttatcta aattacatat aattacatat
     2761 aaaaaattaa agggtatctg gaaagataaa ctatacccta t
//
LOCUS       DAEPKC010000194         2621 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.197, whole genome shotgun sequence.
ACCESSION   DAEPKC010000194 DAEPKC010000000
VERSION     DAEPKC010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2621)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2621)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2621
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.197"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            320..1105
                     /locus_tag="KR294_003689"
     CDS             320..1105
                     /locus_tag="KR294_003689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH0241729.1"
                     /translation="MIVKIDNTLEKEFWQYVSHEESLNLFIIGYVENYGFSSQYQDIW
                     SQVEDGNITSIILKNKSTLIIYSFKNNFNIGEMKNHIKDLDVESISGKKCVIDRLISK
                     YKDFYEKLDNKFCVLKEIKEIDFSNMKEYKIENAQEKDIDEIGKLLNRSDYKVSKNYI
                     EERKVHLKEGNVRAYFIRNDDTMISTVSTGMETSFLAMVVSVSTDKRYRGKGLASYMV
                     YNLSKELLLEGKVPCLFYNNDVAGKIYHNIGYKEINEWTILFK"
     gene            complement(1202..2026)
                     /gene="pdaA"
                     /locus_tag="KR294_003690"
     CDS             complement(1202..2026)
                     /gene="pdaA"
                     /locus_tag="KR294_003690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="delta-lactam-biosynthetic de-N-acetylase"
                     /protein_id="HBH0241730.1"
                     /translation="MKKDSLKKYIMIGAFALILFGIASINFKSLDKTKTQISSPTLDT
                     HEYDWYFNPREDGKQPSPIKEADFFKKYGAYYVGNPNEKVIYLSFDAGYESGNTPKLL
                     DTLKKHNAKAQFFVVESYIKSNPELIKRMEKEGHLVCNHSKSHPSMAGITDFEKFKEE
                     ITSVEKAYKDVTGKEMPKYFRPPMGKFSEQSLKYTQDLGYKSIFWSFAYVDWYEKKQP
                     THEFAKNKIYSRTHPGAIVLLHPNSSTNTEILDEVLTHWEKEGYKLKTLDYLNNKK"
     gene            2247..>2621
                     /locus_tag="KR294_003691"
     CDS             2247..>2621
                     /locus_tag="KR294_003691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HBH0241731.1"
                     /translation="MDNIISVLNDVVFLDIEVSGLDCLNSEILEVGAVKVKDWKIYTY
                     ESLIKNKFEVPVEVFSVCKNLDKNDLEIANEIELVEDRLVNFVEDSFIICHDLSLKKK
                     FLEYHMPKLKNKFIDLIELAVIL"
BASE COUNT         1034 a          247 c          402 g          938 t
ORIGIN      
        1 gtaagatata agtaaataaa tatataacat gactatagaa atttaacttt aaaataactt
       61 atgataattt agaggaggaa tatatatgaa tatatcaaga aaagctatga aaataataga
      121 attagcacaa aaaattgcaa ataagagagg tatttcagta gaagaagctt ggagtgaagc
      181 agtaacagaa tataaaaata aatacgaaca tattgcatag atatttaaaa atttagaata
      241 tttggtagaa tataatgatt ttaaatgata ctataaatta taaggtatat cattattaac
      301 atagaaggag gatatctgct tgattgtaaa aatagataat actttagaaa aagaattttg
      361 gcaatatgta tcacatgaag aaagtttaaa tttattcata attggatacg ttgagaatta
      421 tggatttagc tctcaatatc aagatatatg gtctcaggta gaagatggaa atataacctc
      481 tataatatta aaaaataagt caacacttat aatttatagt tttaaaaata attttaatat
      541 aggagaaatg aagaatcata taaaagattt agatgtagaa agcataagtg gaaaaaaatg
      601 tgtaatagat agactaataa gtaaatacaa agatttttat gaaaaactag ataataaatt
      661 ttgtgtatta aaagaaataa aagaaataga tttttccaac atgaaggagt ataaaataga
      721 aaatgctcag gaaaaagata ttgatgaaat aggaaaactt ttaaataggt cagactataa
      781 agtaagtaaa aattacatag aagaaagaaa agttcattta aaagagggaa atgtaagagc
      841 atattttatt agaaatgatg atactatgat tagcactgtg tcaactggta tggaaactag
      901 ttttttggca atggtggtct ctgtaagtac agataaaaga tataggggaa aaggacttgc
      961 aagttatatg gtttacaatt tgagtaaaga attgttgtta gaaggaaaag ttccatgtct
     1021 tttttataat aatgatgtag caggtaaaat atatcataat ataggataca aagagataaa
     1081 tgaatggaca attcttttta aatagctata aaaaataaaa aactctatcg agaattaaag
     1141 tatttataaa taactatatt tttactataa ttcatgatag agttttttta aatttatgat
     1201 actatttttt attatttaaa taatcaagtg ttttaagttt ataaccttct ttttcccaat
     1261 gtgtaagaac ctcatctaat atctcagtat ttgttgatga atttggatgc agtaaaacta
     1321 ttgcaccagg atgagttctt gaataaattt tgtttttggc aaattcatga gtaggttgtt
     1381 tcttttcata ccaatctaca taagcaaaac tccaaaatat tgatttatat cctaaatctt
     1441 gtgtatattt taaagattgt tcgctaaatt tacccattgg aggtctaaaa tacttaggca
     1501 tttcttttcc agtaacatct ttgtatgctt tttctacact tgtaatttct tctttgaatt
     1561 tttcaaaatc tgtaatacct gccattgatg gatggctttt tgaatgatta caaactaaat
     1621 gtccttcttt ttccatacgc tttattaact ctggattgct ttttatataa ctttcaacta
     1681 cgaaaaattg agctttagca ttgtgttttt taagcgtatc taataatttt ggagtgtttc
     1741 cactttcata tccagcatca aatgatagat atataacttt ttcattggga tttcctacat
     1801 aataagctcc gtatttttta aaaaaatcag cttcttttat aggtgatggc tgtttaccat
     1861 cctccctagg gttaaaatac caatcatatt catgtgtgtc gagtgttgga ctagaaattt
     1921 gagtttttgt tttatctaat gatttaaaat ttatactagc aattccaaaa agtattagag
     1981 caaatgctcc tatcataatg tattttttta ggctatcttt tttcacaatt tcacctctta
     2041 tttaaaattt aaagtatatt tcttataata tagtttgaat atttatagtt aaaaatattc
     2101 acatatacaa ataataaatg aaagaagttt actgtaagat ataaagttga tattaattat
     2161 cttaaataaa gtgtatataa atgataaaat ataaagagaa atgattgtaa ataagttagg
     2221 ctggtttaac ttgaagggat ataaaaatgg ataatataat aagtgtattg aatgatgttg
     2281 tttttttaga tatagaagtt agtggattag attgtttaaa ttcagaaatt ttagaagttg
     2341 gagctgtcaa ggttaaagac tggaaaatat atacctatga atcattaata aaaaacaaat
     2401 ttgaggtacc tgtagaagta ttctcagtat gtaaaaattt agataaaaat gatttagaaa
     2461 tagctaatga aatagaactg gtggaagata gacttgtaaa ttttgtagaa gatagtttca
     2521 ttatatgtca tgatttaagt ctgaaaaaaa agtttcttga gtatcatatg ccaaagttaa
     2581 aaaacaaatt tattgattta attgaattag cagttatttt a
//
LOCUS       DAEPKC010000195         2560 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.199, whole genome shotgun sequence.
ACCESSION   DAEPKC010000195 DAEPKC010000000
VERSION     DAEPKC010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2560)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2560)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2560
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.199"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            636..2432
                     /locus_tag="KR294_003692"
     CDS             636..2432
                     /locus_tag="KR294_003692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002594337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HBH0241732.1"
                     /translation="MKPTMEILTKLQENSKKNHDEVFTRLYRYLLRPDIYYVAYQHLY
                     SNKGAGTKGVTDDTADGFSEIYIENIIEALKNEMYQPKPVRRTYIKKSNGKMRPLGLP
                     VFTDKLIQEAIRMILEAIYEPIFSDYSHGFRPARSCHTALAQIKKEFTGARWFIEGDI
                     KGCFDNINHAVLVEIINQKIKDARFLKLIRSFLKAGYMEDWKYHKTYSGCPQGGIISP
                     ILANIYLNELDRHVMKIKKEFDVATKARYTPEYTKLVGLRQRLHNKIKNSNGIEREKL
                     IEEYKSATAQMLKLPAKQCDDKKIKYVRYADDFLIAVNGNRQDCEKIKQELTEFISTT
                     LKMELSQEKTLITHSNTPARFLGYDVRVRRDQQIKPKGKFKTRSMNNKVELSIPFKDK
                     IEKFLFSNGIVKQRSDNGKLEPIHRPQLLNRTDLEIVTIYNAELRGICNYYGLASNFN
                     KLIYFNYLMEYSCLKTLAGKHRSKVSKIRAMYKDGTGKWAIPYETKTVIKKMYFANYA
                     DCKGKKFTDIVPQTAKNYSHDVTTLESRLKAKICEVCGCTESDRYEIHHVNKVKNLKG
                     KSEWEKIMIAKRRKTIVVCHKCHMAIHHGEKK"
BASE COUNT          977 a          439 c          533 g          611 t
ORIGIN      
        1 ttagaagtag attaaagaaa gggggacaga aaaaaaaggc actaccccgt aagataacac
       61 gggaaaccac ctgcctaacc gaaaggtgaa aactgtacgg gaaaatagca cggcaggaaa
      121 gcagaaagtt gttcaaagac aatagagcac gactgaactg caaggttaag tgaatatgag
      181 gataaaacta gatttgttga atgtgagttc caaacctctg ttacgtgtgg acacaggaaa
      241 cttgtctgaa acctgtggta tgagtaacgc tgaaaataaa tgcctttcag tgggttatca
      301 attaactcat acggtacgct ggagaaccag tagtaacgga acgaaagcat atccgacaat
      361 tcacaccagc ctactacttt cgtcaactgg agattaccta aaccagaatg cctacaatgg
      421 ctatgtgtaa tgctcttgta gtgataaatc acaaggctat gctaagtgag atgacgctga
      481 aaatctggca aggtaacgga gctttcatag tagtctgaga accctgaaaa gacagggaaa
      541 gccgtaaaat cggatacggg aaaaccgttc acatggcgaa ggaaagcagt cttagcgaat
      601 taaaattaga aattgattag ggaggaaaac ctcaaatgaa accaacaatg gagattttaa
      661 ccaaattaca ggaaaattca aaaaagaacc atgatgaagt atttacaagg ctctatcgat
      721 atttactccg tccagatata tactatgttg catatcaaca cctctactcc aacaaaggag
      781 caggaacaaa gggtgtaaca gacgacacag cggacggttt tagcgaaata tatattgaaa
      841 atatcattga agccttaaaa aatgaaatgt atcaaccaaa accagtaaga cgtacataca
      901 tcaaaaaatc aaatggcaaa atgcgtccct taggactgcc tgtctttact gataagctga
      961 tacaggaagc aatacgcatg atattagaag caatctatga gcctattttt tcagactact
     1021 ctcacggttt ccgaccagca agaagttgtc atactgctct tgctcaaata aaaaaagaat
     1081 ttacaggagc acgctggttt atagagggcg acataaaagg gtgctttgat aacatcaatc
     1141 atgcggtact tgtggaaatt atcaatcaga aaattaaaga tgcacgtttt ctgaaactca
     1201 ttcgttcatt cttaaaggca ggttatatgg aagattggaa ataccacaaa acatatagcg
     1261 gttgccctca aggtggcatc atttcgccta ttcttgcgaa tatctacctt aatgaattag
     1321 accgtcacgt aatgaagata aagaaagagt ttgatgtggc aacaaaggca cgttatacac
     1381 cagaatatac aaaactggta ggactacgcc aaagattaca caacaaaatt aaaaatagca
     1441 acggtataga aagagaaaag ctgattgaag aatataaatc tgcaacggct caaatgctta
     1501 aactaccagc gaagcaatgt gacgacaaga aaataaaata tgtgcgttac gctgatgatt
     1561 tcctaatagc tgtgaatggc aatcgacagg attgtgagaa gattaagcaa gaacttacag
     1621 aatttataag taccacatta aaaatggaac ttagtcaaga aaaaactctg attacacaca
     1681 gtaatactcc tgctcgtttt ctcggatatg atgtcagagt acgccgtgac cagcagatta
     1741 aaccaaaagg aaaattcaaa acccgttcta tgaataacaa ggtggaattg agtattccat
     1801 tcaaagacaa gatagagaaa tttttatttt caaatggaat tgtaaagcag aggtcagaca
     1861 atgggaaatt agaacctata caccgaccac aactgcttaa taggacagat ttggaaatag
     1921 tgactattta taatgcagaa ttaagaggta tctgtaatta ttatgggttg gcaagcaatt
     1981 ttaacaagct aatctatttc aattatctta tggaatatag ctgtttgaaa acacttgcag
     2041 gaaagcaccg ttccaaagtt tctaaaatta gagctatgta taaagacggt acaggcaaat
     2101 gggctattcc ttatgaaact aaaacagtaa taaagaaaat gtattttgcg aattatgctg
     2161 actgcaaagg aaagaagttt actgatattg ttccacaaac agctaaaaat tattcccatg
     2221 acgtaacaac attagaaagc cgattaaagg cgaagatatg tgaagtatgt gggtgtacgg
     2281 aaagtgacag atacgaaatt catcatgtaa acaaggttaa aaaccttaaa ggaaaatcag
     2341 aatgggaaaa gataatgata gccaaaagac ggaaaacaat cgtggtatgc cacaagtgtc
     2401 acatggctat acatcatggc gaaaagaaat aacctgtaac ggagcaaaga tggagagccg
     2461 tgtgcattga gaaatgcaag cacggttcgg ggagaggact gcacaaacct accctagaaa
     2521 taaggaaagg cggtgctttc ctactctact atgtgggaaa
//
LOCUS       DAEPKC010000196         2275 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.200, whole genome shotgun sequence.
ACCESSION   DAEPKC010000196 DAEPKC010000000
VERSION     DAEPKC010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2275)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2275)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2275
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.200"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(<1..192)
                     /locus_tag="KR294_003693"
     CDS             complement(<1..192)
                     /locus_tag="KR294_003693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0241733.1"
                     /translation="MNLKDFNGKRLKSARIFRAKTIEQLSKETKINKKDLKAFEENKY
                     VPNIENTLKLSNILNFPKEY"
     gene            complement(345..1298)
                     /gene="msrA"
                     /locus_tag="KR294_003694"
     CDS             complement(345..1298)
                     /gene="msrA"
                     /locus_tag="KR294_003694"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HBH0241734.1"
                     /translation="MIKLATFAGGCFWCMVKPFDKYDGVIKVVSGYTGGHVENPTYQE
                     VCSGTTGHLEAIQITYDDDIISYDELLNIFWKQINPTDDGGQFGDRGTQYKTAIFYHD
                     EEQKNIALESREHLENSKIFDSKIVTDIIPATKFYEAEENHQDYYKKRPLNYNMYYKG
                     SGRYNFVKSHWDGNNINREELKKTLTHIQFEVTQNDMTEVPFENEYYDNNKEGIYVDI
                     VSGEVLFSSKDKFDSGCGWPSFSKPVIDKSIIERSDFSQGMYRVEVRSAKGNSHLGHV
                     FDDGPKELGGLRYCINSASLKFIPRENMEALGYGEYLKLFE"
     gene            complement(1422..>2275)
                     /locus_tag="KR294_003695"
     CDS             complement(1422..>2275)
                     /locus_tag="KR294_003695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HBH0241735.1"
                     /translation="ALSISILERIVKEYPNLLNNINMFGGTSTGSLIALGLAYGVSPK
                     EIKELYSIENSKYIFNKSYAEILRPKYENKNLKEVLLSIFPEELELKDLNKLVMIPSF
                     YIGNEENAWKPVFYNNMPNSFTKTSKVVDVAMASSAAPVFFPTYNRHVDGGIIATDPS
                     LACIIHAIDSGFKLKNTRLFSIGTGYVYNSIKADTTEWGAIDWIINKEPDLPIISITL
                     EGNSQMSQLFSQKLLGDNYYRLNPKMEKDVAMDDCDALEYLMSLGENCDIKDAFGWIK
                     KKSFYRN"
BASE COUNT          722 a          409 c          234 g          910 t
ORIGIN      
        1 atactctttt ggaaaattta atatattaga taattttaat gtattttcta tatttggtac
       61 atacttattt tcctcaaaag cttttaaatc ttttttattt attttagttt ctttagacaa
      121 ctgttctatc gtctttgctc taaaaattct agctgatttt aatctctttc cattaaagtc
      181 ttttaaattc atttgttttc tctctttcaa aattaaattc ttaatctatt ggtataaata
      241 agattacaat taataattta tcatattatt gacaaaaaaa caaaaggtga aaatattttt
      301 ttatattttc accttttaga taagtttata ataaatattc ctaattactc aaaaagtttt
      361 aaatattctc catatcctaa agcttccata ttttctcttg gtataaattt aagagaagca
      421 gaatttatac aatatcttaa acctccaagt tcttttggac catcatcaaa tacatgacct
      481 aaatgagaat ttcctttagc acttcttact tcaactctgt acataccttg tgagaaatca
      541 cttctctcaa tgatagattt atctataact ggctttgaaa aacttggcca cccacatcca
      601 gaatcaaatt tatcttttga agaaaataac acttctccac ttacaatatc aacataaatt
      661 ccctctttgt tattgtcata atattcattt tcaaaaggta cttctgtcat atcattttga
      721 gtgacttcaa attgtatatg agttaaagtc ttttttaact cttccctatt tatattgttt
      781 ccatcccaat ggctttttac aaaattatat cttccagacc ctttataata catattgtag
      841 tttaatggtc ttttcttata ataatcctga tgattttctt ctgcttcgta gaatttagtt
      901 gctggaatta tatcagtcac tattttacta tcaaatattt tactattttc cagatgttct
      961 cttgactcta aagctatatt tttttgttct tcatcatgat aaaatatagc agtcttatat
     1021 tgagttcccc tatcaccaaa ttgtccacca tcatctgtag gattaatctg tttccagaag
     1081 atatttagaa gttcatcata acttattata tcatcatcat atgttatttg aattgcttct
     1141 aaatgaccag tagttcctga gcatacctct tgatatgtag ggttttcaac atgaccacct
     1201 gtatatccag aaactacttt aataactcca tcatacttat caaaaggttt taccatacac
     1261 caaaaacatc cacctgcaaa agtagcaagt tttatcattt tcatcactcc ttaaataaat
     1321 tatactttat ttattcccta agaagtaact taataatctg cattttatta tttttaccta
     1381 ctcaatgaaa tcatgtgtaa aaatacaatt gcaaattgaa tctaatttct ataaaagctc
     1441 tttttcttta tccatccaaa agcatctttt atatcacaat tttctcctaa agacattaga
     1501 tattctaatg catcacaatc atccatagct acatcttttt ccatcttagg atttaatcta
     1561 tagtaattat ctccaagaag tttttgagaa aataactgac tcatttgaga atttccttct
     1621 aaggtaatag atataattgg taaatcgggt tctttattaa ttatccagtc aatagctccc
     1681 cattcagtag tatctgcctt tatactgtta tatacatatc cagtccctat tgaaaaaagt
     1741 cttgtattct taagtttaaa tccactgtca atggcatgaa ttatacacgc taaactcggg
     1801 tcagttgcta ttattcctcc atcaacatga cgattatatg ttggaaaaaa taccggagca
     1861 gcactacttg ccattgctac atctacaact ttgctagtct ttgtaaaaga atttggcata
     1921 ttgttataaa acactggttt ccatgcattt tcctcatttc ctatataaaa acttggtatc
     1981 attactaatt tatttaaatc ttttaattct agttcctctg gaaatatact taataaaact
     2041 tcttttaagt ttttgttttc atactttggt ctgagtattt ctgcataact tttattaaaa
     2101 atatactttg aattttcaat tgagtaaagt tcttttatct ctttagggct tacaccatac
     2161 gcaagcccta gtgcaattag actccctgta gatgtacctc caaacatatt tatattgttt
     2221 aatagatttg gatactcttt tactatcctc tcaagtatgg atatactcaa tgccc
//
LOCUS       DAEPKC010000197         2268 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.201, whole genome shotgun sequence.
ACCESSION   DAEPKC010000197 DAEPKC010000000
VERSION     DAEPKC010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2268)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2268)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2268
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.201"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            336..1955
                     /locus_tag="KR294_003696"
     CDS             336..1955
                     /locus_tag="KR294_003696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HBH0241736.1"
                     /translation="MNIVISLIGGLGLFLYGMSLMGEGLQKSAGDKLKKIIELLTSNV
                     VMGVLVGTVVTGIIQSSSATTVMVVGFVNAGIMNLSQAIGVIMGANIGTTVTAQLVSF
                     NLEGIAPIALGIGILFYLFTSNQKTKHLSEILIGFGILFTGMEFMKDAVAPLAEYKAF
                     TDALLYFSKNPVLGILAGFAITGIVQSSSASMGMLIALASQGILPLSSALPILYGDNI
                     GTCVTSLLSSVGASRNARRAAVMHLSFNVIGTIIFMLVLNKPISAIVTHFDPTDTARQ
                     IANAHTLFNLTNVIILLPFSKYIVKLANRLIPIKETESEIVNNTKYLDERMFSTPSIA
                     LGNTVQEVVRMGHKATNSLEHSIAGFLNKSNEDINKAFESEKVVNKLQKDILNYLLKL
                     SKEPLRDDEHFRTDLLFNTVNDIERVSDHAENIAELAMSVKEMNISFSDSAIREIYEI
                     YNKTITNFKDALIVLDVKDFELANKVLEVENEVNYLEKTFRNSHMIRLNNGSCTIDAG
                     VLYLDLLTNLERISDHSTNIVKQVLKLKQKI"
BASE COUNT          842 a          272 c          325 g          829 t
ORIGIN      
        1 attgaatata aaaatattta taactaaaaa atatcattct aaaaggatgt tattttttta
       61 catatttttt acaattatag ttaattcttt gttaaattgt ttgtacataa aatactaaaa
      121 atctaagttc aagtatttaa attgctatat atcataaatt ttctaaaatt aacaacaact
      181 taaaaattta acattctctt aacgtatact taacaaaaca ttaatatttt tattgacaaa
      241 atttgttatt ctatattatg gaaacaataa attttagtta ataaagttta taattcagat
      301 aaaaaaatta ttaatttctt aagggaggaa atatcgtgaa tatagtaatt agccttatcg
      361 gtggacttgg actttttctt tacggaatga gtttaatggg agaaggttta caaaaatcag
      421 caggagacaa attaaaaaaa attattgaac tcttaacaag taatgttgtt atgggtgtac
      481 tggtaggtac agtcgttaca ggtattatac aaagttcaag tgctactact gttatggttg
      541 taggatttgt aaatgcaggt ataatgaatc taagtcaagc tattggtgta ataatggggg
      601 caaatatagg tactacagtt actgctcaat tagtttcatt taatcttgaa ggaattgcac
      661 caattgcttt aggtataggt attttattct atttatttac atcaaatcaa aaaacaaagc
      721 atttatctga gatacttata ggttttggta tattatttac aggaatggag tttatgaaag
      781 atgcagtagc tccacttgct gaatacaaag cattcactga tgcactttta tattttagta
      841 aaaatcctgt attaggtata ttggcaggat ttgccataac tggtattgtt caaagttcaa
      901 gtgcatctat gggtatgtta atagcactag cttctcaagg aatacttcct ctatcatctg
      961 ctttacctat tctttatgga gataatatag gtacttgtgt tacttcactt ttatcaagtg
     1021 ttggtgcaag tagaaatgct cgacgtgcag ctgtaatgca tttaagtttt aatgtaattg
     1081 gtacaataat atttatgctt gttttaaata aacctatatc agccatagtt actcattttg
     1141 acccaactga tacagctaga caaatagcaa atgcacatac tttatttaat cttacaaatg
     1201 ttataatatt attaccattt tctaaataca tagttaaatt agcaaataga cttataccta
     1261 ttaaagaaac tgaatcagaa atagtaaata atactaagta cttagatgaa aggatgttta
     1321 gcactccatc tatagcactt ggtaatactg tacaagaagt tgtaagaatg ggtcataaag
     1381 ctacaaactc tttggaacat tcaattgcag gatttttaaa taagagcaat gaagatatta
     1441 ataaagcttt tgagtcagaa aaagttgtca ataagttaca gaaagatata ttgaactatt
     1501 tgttaaaact ttctaaagaa cctcttagag atgatgaaca ctttagaaca gatttgcttt
     1561 ttaatactgt aaatgacatt gaaagagtct ctgaccatgc agaaaatata gctgaattgg
     1621 ccatgagtgt taaggaaatg aacattagtt tttctgatag tgcgataaga gaaatatacg
     1681 aaatatacaa taagacaatt actaatttta aggatgcctt aatagtttta gatgttaaag
     1741 attttgagtt agcaaataaa gttttagaag ttgaaaatga agtaaattat ttagaaaaaa
     1801 cttttagaaa ttcacatatg attagactaa ataatggaag ttgtacaatt gatgctggtg
     1861 tactttatct tgacttactt actaatctag aaagaatttc tgaccactca acaaatatag
     1921 taaaacaagt actaaaactt aaacaaaaaa tatagtgatt atttttatat ataatcttaa
     1981 tcaatgagaa gtaagaagct atagataatg cttatatcat ttatggtttc ttatttttta
     2041 tgtaatactc aaatttttat agtattctct tattattaaa caatttctgc ctagaatatt
     2101 ccatatatat atgacttctt tcataaaact tgaactgccc ataactaaag tcacaagtat
     2161 acataactat tttttaatca attataacca atatttgttt tatttatctt cattttaatt
     2221 cttcattcaa taatgtaata agattatttt ttatttggat actattat
//
LOCUS       DAEPKC010000198         2199 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.202, whole genome shotgun sequence.
ACCESSION   DAEPKC010000198 DAEPKC010000000
VERSION     DAEPKC010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2199)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2199)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2199
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.202"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            175..2187
                     /locus_tag="KR294_003697"
     CDS             175..2187
                     /locus_tag="KR294_003697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH0241737.1"
                     /translation="MKKSVALVNDSRKDLIDFLENNLKLVFGDSININRYFINEINDN
                     DIINDDVILVMSVERLDKIINNILDKKKVIVVRRTFREDKIYNLLSLPQGTNVLIVND
                     SDETTLETISLFYKIGVTNIRPIPYMNDNNYKNIKIAITPGVPEKVPSFISDIFDLGH
                     RYIDISTFIEIINLLQIDSKEIQSNLVKYSEEIISLDTGIKDKYKELFLKIEELDTIL
                     NLSKDGILFTSKDGEINTYNSKVKDILDINEDIYGKYIEDIFVDSLKVLLSEKEILDK
                     VVVFNKKYINVNKKNIYNRDEKMGTYYSLQEITYIKKLEQNLTKKLREKGQIAKYTFK
                     DIKTNSPKMFECIDLAKKVSKSDLSILIRGESGTGKELIAQSIHNNSNRKNQPFIAVN
                     CAAVPENLLESQLFGYDKGTFTGGLKDGKQGLFELANNGTIFLDEIGDMPLELQTKLL
                     RVLQEKQIMPVGSHNVINIDVRIISATNKNLEQMIDNSQFREDLYYRLNTIPINIPPL
                     RERKEDILIIMEDLINKKLVITPEAKKLIQNYMWKGNIRELQNVTSYLNIMCEDIVLE
                     KDLPPNLRSSDNKNTSLKLKYSKNDILNILEILILNKESDVGIGRGLILKALLDKNLQ
                     ITEGKIKKIFEYLKKEELIICSSGRYGSKITQKGEDFYNKLKYKGL"
BASE COUNT          984 a          211 c          323 g          681 t
ORIGIN      
        1 ttagggggat ttggtgacaa gatttttaac tataagaaag aaagtgtctt aatgcaactt
       61 ttagaaagtc attatagaca ctttcttttt tatttgataa atttaaatta tcaaaattag
      121 attgctttat acaactattt tgttggaaac tatttattat ataaggagaa ataaatgaaa
      181 aaatcagtag ctctggtaaa tgatagtaga aaagatttaa tagacttttt agaaaataat
      241 ttgaaattag tttttggaga ttctataaat attaatagat acttcataaa tgaaataaat
      301 gataatgata ttataaatga tgatgtgata ttagtaatgt cagtagaaag attagacaaa
      361 attataaata atatactaga taagaaaaaa gtgattgtgg taagaagaac ttttagggaa
      421 gataaaattt ataatctact atctttacca cagggtacaa atgttctaat cgtaaatgat
      481 tctgatgaaa ctactctaga aactataagt ttattttata aaattggagt gactaatatt
      541 agaccaattc catatatgaa tgataataac tataaaaata taaaaatagc tataactcca
      601 ggagttccag aaaaagtacc tagctttatc tcagatatat ttgatttagg tcacagatat
      661 atagatatct ctacatttat agaaataata aatttattac aaattgattc aaaggaaata
      721 caatctaatc tagttaaata ctcagaagaa ataataagtt tagatactgg tataaaagat
      781 aaatataagg aattattttt aaaaatagaa gaattagata caatcttgaa tttatcaaaa
      841 gatggtatat tatttacttc aaaagatggt gaaataaata catataatag taaagtaaaa
      901 gatattttag acataaatga ggatatatat ggaaaataca ttgaggatat atttgtagat
      961 agtttaaaag ttttattgag tgagaaagag atactagata aagttgtcgt attcaataag
     1021 aaatatataa atgtaaataa aaaaaacata tacaatagag atgaaaaaat gggcacatat
     1081 tatagtttac aagaaataac atacataaaa aaattagaac aaaatctcac taaaaaatta
     1141 agagaaaaag gacaaatagc aaaatataca tttaaggata taaaaacaaa tagtcctaaa
     1201 atgtttgaat gtatagattt agctaagaag gtttctaaat ctgatttaag catacttatc
     1261 agaggtgaaa gtggaactgg taaagaactc atagctcagt ctatacataa caactcaaat
     1321 agaaaaaatc aaccctttat agcagtaaat tgtgcagccg ttcctgaaaa tttattagaa
     1381 agccagctat tcggatatga caagggaact tttactggag gtctaaaaga tggaaaacaa
     1441 ggattatttg aacttgctaa taatggaaca atattcttag atgaaatagg cgatatgcct
     1501 ttagaattac aaacaaaact acttagagtt cttcaagaaa agcagataat gcctgttgga
     1561 tctcacaatg taattaatat agatgttaga atcatatctg ctacaaataa gaatttagaa
     1621 caaatgattg ataatagcca atttagagag gatttatatt atcgattaaa tacaattcca
     1681 ataaatatac ctcctctaag agaaagaaaa gaagacatat taattattat ggaagattta
     1741 attaataaga aattagtaat cacaccagaa gcaaaaaaac ttatacaaaa ctatatgtgg
     1801 aaaggtaata taagagaact ccaaaatgtt acatcctatt taaacattat gtgtgaagat
     1861 attgtattag agaaagattt acctccaaac ttaaggtctt cagataacaa aaatacatca
     1921 ttaaaactaa aatatagtaa gaatgatata ttgaatatat tagagatact aattttaaat
     1981 aaggaatcag atgttggtat tggtagagga ttaattttaa aagcactact cgataagaac
     2041 cttcaaatta cagaaggaaa aattaaaaaa atatttgaat atctaaaaaa agaagaactt
     2101 ataatttgta gttcaggaag atatggaagt aaaataactc aaaaaggaga agatttttac
     2161 aataaattaa aatataaagg tctataaaat tataattta
//
LOCUS       DAEPKC010000199         2166 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.203, whole genome shotgun sequence.
ACCESSION   DAEPKC010000199 DAEPKC010000000
VERSION     DAEPKC010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2166)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2166)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2166
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.203"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            322..696
                     /locus_tag="KR294_003698"
     CDS             322..696
                     /locus_tag="KR294_003698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH0241738.1"
                     /translation="MNIVISNSSGKPIYEQITTQIKSMIISGELPEGSALPSMRLLAK
                     ELRISVITTKRAYSDLERDGFIETVTGKGSFVSSKNMDFVKEEQFRLIEEYLQKAVDT
                     AKSSDITYDELKDILFLLYKGE"
     gene            693..1556
                     /locus_tag="KR294_003699"
     CDS             693..1556
                     /locus_tag="KR294_003699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0241739.1"
                     /translation="MISMDAITIKNLNKTYKDFSLQDISFSVPKGSVMGFVGENGAGK
                     TTTLKAILNLISYDSGNIEIFGLDSKKNEKEIKEQIGVVFEGSNFHENLNTDHVSKIM
                     SKIYKNWNDTLFKDYLKKLRVPDNKLIKEFSKGNKMKLSIAVALSHKPKLLILDEATS
                     SLDPIVREEILDIFLDFIQDEEHSIILSSHITSDLDKIADYITFIHKGKIVFSENKDE
                     LIDTMGVLKCKPSDFDNLSREDYSYYRKSQFGYEVLLKDKHRFISRHPNCIVDNTSIE
                     EIMLFYVRGDK"
     gene            1556..>2166
                     /locus_tag="KR294_003700"
     CDS             1556..>2166
                     /locus_tag="KR294_003700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 transporter permease"
                     /protein_id="HBH0241740.1"
                     /translation="MKGLILKDLLNLKGNIKFILLFIIMFGFMSSLGDGNVNNFIGVI
                     IVLCTTMIVSTFSYDDLNKWDSYVLTMPINRNDIVLSKYLTMLIFSFIGVLVSLIVSV
                     TIGYFKNTLILNETLLINALILSISVCFGSLILPLIYKFGTERARLLMILCFLVPTLA
                     LLVFKSILENISSPISIEIILNTLVYSLPFVAILLFVISYFISS"
BASE COUNT          827 a          226 c          318 g          795 t
ORIGIN      
        1 aatatattac aaaaaaatat gtatgtcaaa actgaaaatg caaaaagttc accttataag
       61 taaactttta tttagctata agctaaactt tattattttt ttaatttagt atttccaatt
      121 tattggcagg atttttgaac aatatttata aattttttaa aaaaatttaa atctatttaa
      181 tatggcagac tttcataaaa tacattacat ttattaaatg tataatattg gcaattagtt
      241 ttttctaaaa tcagttgaca tattatatat atatttatat aatgtgtata tactatatat
      301 acaatttaag gaggtgtctt attgaatata gttattagta attcgagtgg gaagccaata
      361 tatgaacaga ttactacaca aattaaaagt atgattataa gtggagagtt accagaaggc
      421 tcagctcttc caagtatgag actattggca aaagaactta gaataagtgt aattactaca
      481 aaacgagcat atagcgattt agaacgagac ggatttattg agacagttac tggtaaaggc
      541 agttttgtat ctagtaaaaa catggatttt gtcaaagaag aacaatttcg tttaattgaa
      601 gaatacctac aaaaagcagt tgatacagca aaaagtagtg atattacata tgacgaatta
      661 aaagatattt tatttttatt atataaagga gaatgataag tatggatgca ataactataa
      721 aaaatttaaa taaaacttat aaagatttta gcctacaaga tatatctttt tcagtaccaa
      781 aagggagtgt aatgggattt gtaggtgaaa atggtgcagg aaaaacaact acattaaaag
      841 caattttaaa tttaatatct tatgatagtg gaaatataga aatctttggt cttgatagta
      901 aaaaaaatga aaaagaaatt aaagagcaaa ttggggttgt atttgaggga agcaactttc
      961 atgaaaattt aaacactgac catgtttcaa aaatcatgag taaaatctat aaaaattgga
     1021 atgacacatt atttaaagac tacttaaaaa aattgagagt accagacaat aaattaatta
     1081 aggagttttc aaaggggaat aagatgaaac ttagtattgc tgtagcctta tctcataaac
     1141 caaaattatt aatactagat gaggcaacta gttcacttga ccctatcgtt cgtgaagaaa
     1201 tactagatat atttttagat tttatacaag atgaagaaca ctctattatc ttatcttcac
     1261 atattacaag tgatttagat aagatagcag actatattac atttatacat aaaggaaaaa
     1321 ttgtatttag tgaaaataag gatgaattaa ttgatactat gggagtttta aaatgtaaac
     1381 ctagtgattt tgataacctt tcaagagagg attattcata ttatcgtaaa agccaatttg
     1441 gatatgaagt acttcttaaa gataagcata gatttatctc aagacatcca aactgtattg
     1501 ttgataatac gtctatagaa gaaattatgt tattttatgt gagaggtgat aaataatgaa
     1561 aggtctaatt ttaaaagatt tacttaattt gaaaggaaat ataaagttta tacttttatt
     1621 catcattatg tttggcttta tgtcttcttt aggagatgga aatgttaata actttatagg
     1681 tgttattata gttttatgta ctacaatgat tgtttcaaca ttttcatatg atgatttgaa
     1741 taaatgggat agttatgtac ttacaatgcc tattaatcgc aatgatattg tattaagtaa
     1801 atatttaact atgttaatat ttagctttat aggtgttctt gtttcactta ttgttagtgt
     1861 aactattggt tattttaaaa atacacttat attaaatgaa acactactta ttaatgcact
     1921 aatcttatca atttcagtat gttttggtag ccttattcta ccacttattt ataaatttgg
     1981 tacagaaaga gctcgtttat taatgatttt atgcttttta gttccaacac tagctttatt
     2041 agtttttaaa agtattttag aaaatattag ttcacctatt tctatagaaa ttatacttaa
     2101 tacactagta tattctcttc catttgttgc tattttacta tttgtgattt catattttat
     2161 atcatc
//
LOCUS       DAEPKC010000200         2072 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.204, whole genome shotgun sequence.
ACCESSION   DAEPKC010000200 DAEPKC010000000
VERSION     DAEPKC010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2072)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2072)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2072
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.204"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     repeat_region   2..425
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=2..30
                     /rpt_unit_seq="atttacataccacttagttaatataaaac"
     gene            complement(955..1059)
                     /locus_tag="KR294_003701"
     CDS             complement(955..1059)
                     /locus_tag="KR294_003701"
                     /inference="COORDINATES: protein motif:HMM:NF024729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBH0241741.1"
                     /translation="MDDYIYYYNNFRYQNRLNSMSPFEFRKYLSTERA"
     gene            1684..1929
                     /locus_tag="KR294_003702"
     CDS             1684..1929
                     /locus_tag="KR294_003702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241742.1"
                     /translation="MNQKKIKISIKMVIIGIFAVIIAFVLSRLFVEYIDELLRSNWQY
                     QLFESESSYIVFANCIMFSNILLEIFLIYICRKFRKI"
BASE COUNT          824 a          276 c          223 g          749 t
ORIGIN      
        1 aatttacata ccacttagtt aatataaaac gctactaaac ttgatataca tgaccattat
       61 aataataaat ttacatacca cttagttaat ataaaacttc cataaaaaca tccccttttt
      121 attcttcttc cttatattta cataccactt agttaatata aaacagtctt tttttaatgc
      181 agagatgcaa gaagttttat aatttacata ccacttactt aatataaaac tatcagtatt
      241 taagtaataa tttaagtaat ataggattta cataccactt agttaatata aaacggtcac
      301 tacaacttat acttccagtc taacgatttg aatttacata ccacttagtt aatataaaac
      361 atattttgga tttattaata taaacataat taaaaaattt acataccact tagttaatat
      421 aaaaccccaa aataaactgg gcattttcaa tacttacaca tatgcaactc tcttaaattt
      481 gcagtgaacc atgagtagtg caaatgataa agcttatcat ataccctcaa caccttatat
      541 ttcaagcgtt aagctctact ttgtaacaaa tatcgctcac tgcaaaacta tttacatttt
      601 tattatatca taaatatatt atttttgaat atctatacca atttgtggta taataaaagc
      661 aagaagaact acaatctatt tagacgtaga gtgaagttca aatactaatg tttattcttt
      721 ttgaacttga tttttagttc aaaactaaag tcactcctgc ctgtgtgaac tatacccgct
      781 gttttataca gttaaaacat gtaaaaatag ttataaagta ctagtgtaac tcattagtac
      841 tctttttatt atattcatat aattaatatc tatattttaa agtttactat ctaaaaaaga
      901 gcacgtcaaa taaaacccta gatatttaat ttttttagag atacttaaaa taaattatgc
      961 tctctctgta cttaaatatt tcctaaattc aaatggagac atagaattta atctattttg
     1021 atatctaaaa ttattatagt agtatatata atcatctatt gctttaacta attattcata
     1081 tgtatcaaat ttccttaaat agtacatttc tacctttaaa attccccaaa atccttccat
     1141 aggagcattg tcaaggcaac gaccaactct tgtataatat atgtatatct aacaccatta
     1201 agaaatatat attttataat atatatttct tcatttaatg cacttagaaa agcaaagaaa
     1261 atacagatta gtacactttt tagagaaaaa taaaattaat acatctaaaa tattaaaaaa
     1321 tactttagat aatctaaaga cacatctcaa agtttttaac taaattataa aactaattac
     1381 aaatgctatg taacgataat aaataaaaaa tttacttcgc ttaagcgacg tgtcgttgaa
     1441 atatttcatg ttgccaactg gttcgtaagt tgataagaaa agaacactaa ttatttagag
     1501 ttcttttctt agctacaagt ggattataat acttttaaat ctgtgagaaa atcatatata
     1561 ataatgatat gaacaagtaa agaaaataca aaaatgacaa aattataaat aaaatattat
     1621 aaaatcataa ggtcataatt gttatattgt agaaacaaag taaagagaga gggtggagaa
     1681 taaatgaatc aaaaaaaaat aaagattagt attaaaatgg taattatagg tatatttgct
     1741 gtaattattg cttttgtatt atccagatta ttcgttgagt atattgatga attattaagg
     1801 tctaattggc aatatcagct atttgaaagt gagagttcat atatagtatt tgccaattgt
     1861 attatgttct cgaatatatt attagaaata tttttaatat atatttgtag aaaatttaga
     1921 aaaatctaat atggtcaacg tatttcgaat cgaatacttc atgattattt agtctattgt
     1981 gctagttaaa gtttaattcc catataaagt aaattgattt tagtaaaaca aatcacccct
     2041 aagggttagt ttatggataa gtcatccaaa ta
//
LOCUS       DAEPKC010000201         2051 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.205, whole genome shotgun sequence.
ACCESSION   DAEPKC010000201 DAEPKC010000000
VERSION     DAEPKC010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2051)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2051)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2051
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.205"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(133..684)
                     /locus_tag="KR294_003703"
     CDS             complement(133..684)
                     /locus_tag="KR294_003703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0241743.1"
                     /translation="MSINTVIAKNLNRLRNERNLSLGQLAELSGVSKVMLSQIEKGDS
                     NPTVNTIWKIASGLNVPYTAILEQPQNETFIVSKTDIDVQVSENKDYRLYCYYPNTPT
                     RNFELFQMELEEGHSYTSVGHSEKSQEYIMIIEGQLKLEVNDSIYQLRENDSICFSAE
                     SIHTYHNQGEKTLKAVIINYYPV"
     gene            875..1837
                     /locus_tag="KR294_003704"
     CDS             875..1837
                     /locus_tag="KR294_003704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase family protein"
                     /protein_id="HBH0241744.1"
                     /translation="MRVLNNVTEAIGNTHMLHLSKIADEFGVQGNIYAKMEYLNPGFS
                     KKDRVALQMITEAENAGLLVPGQAVVELTSGNTGTGLAIACACKGYKFIACMSKGNSM
                     ERARMMKALGAEVVLVDQMPNSVHGQVSGEDLALVEIEAQKIAKERNAFRADQFNLEA
                     CNHAHEKYTAEEMWEQLDGNIDVFVDFLGSGSTFAGCSKTLKKHNSSIKCYVVEPETA
                     AIYSGKEITDQGHKIQGGGYSMDLPLVDKKLIDGYIQVTDEEATDVARKLAKLEGVFA
                     GFSSGANVCAAIKLLKSSEKGKNIVLTLNDSGLKYLSTDLYEEL"
BASE COUNT          760 a          230 c          359 g          702 t
ORIGIN      
        1 ataacataat tgataaaagt gtaaagatat ataatgaatt tataaagaaa aataaaataa
       61 aaaagataaa tcctaatcaa aggatttatc tttttgtata gaaaataatt attctattat
      121 taaatggcat ggctaaactg gataataatt tattattact gctttcaatg ttttttctcc
      181 ttgattatgg tatgtatgaa ttgattcagc tgaaaaacaa atagagtcat tttctctaag
      241 ttgataaata gagtcattta cttctaattt taattgacct tctataatca taatatattc
      301 ctgtgatttt tcagaatgac caacagatgt ataactatga ccttcttcta attccatttg
      361 aaataattcg aagtttctag ttggtgtatt gggataataa caataaagac gataatcttt
      421 attttctgaa acttgtacat ctatatcagt ttttgataca ataaaagttt cattttgagg
      481 ttgttccagt attgcagtat atggaacatt tagtccactt gcaattttcc aaattgtgtt
      541 tactgttggg tttgagtctc ccttttcaat ttgagaaagc attactttac ttacgccaga
      601 taattcagca agttgaccta gacttaagtt acgttcatta cgtaatctat ttaaattttt
      661 agcaataaca gtattaatac tcatagtagc tccttaaaat gtaaattatt gacaaatata
      721 atttacgaat gtataattta tttaacatta tttataattt acaaatgtat aatataatga
      781 acgttaaata cactgtacat ccgtaatata aattatactg cataaagagt tgtttttcaa
      841 cggatgatag ttgagagatt aagggggaat tgtaatgcgt gtacttaata atgttacaga
      901 ggctataggc aatactcata tgttacattt atccaaaata gcagatgaat ttggagttca
      961 aggtaatatt tatgcaaaga tggaatactt aaatccggga tttagtaaaa aggaccgtgt
     1021 agcattacaa atgattaccg aagcagaaaa tgcaggttta ttagttccag gtcaagcagt
     1081 tgtggaatta acaagtggta atactggaac aggactagca atagcttgtg catgtaaagg
     1141 atataaattt atagcgtgta tgtcaaaagg aaattctatg gaaagagcaa gaatgatgaa
     1201 agctttaggt gctgaagtag ttcttgtaga ccaaatgcct aattcagttc atggacaggt
     1261 atctggtgaa gatttggcac ttgtagaaat tgaggctcaa aaaatagcaa aagaaagaaa
     1321 tgcatttaga gcagaccaat ttaatttaga agcttgtaat catgcacatg aaaagtatac
     1381 agcagaagaa atgtgggaac aattggatgg aaatattgat gtatttgtag attttcttgg
     1441 aagtggtagt acttttgcag gatgttcaaa aacacttaaa aaacataatt cttctatcaa
     1501 atgttatgtt gttgaacctg aaacagcagc aatttattca ggtaaagaaa taactgacca
     1561 agggcataaa atacaaggtg gaggatattc tatggatttg ccattagtag acaagaaact
     1621 tattgatggt tatattcaag ttacagacga ggaggcaact gatgtagcaa gaaaattagc
     1681 taaattagaa ggtgtatttg caggattttc ttcaggggca aatgtatgtg cagcaattaa
     1741 gttgttaaag agcagtgaaa aaggaaaaaa tatagtttta actcttaatg atagtggttt
     1801 aaaatattta agtactgatt tatatgaaga attgtaataa tagcacaata gttatgcaat
     1861 gttttttaaa ttaagtatat agatttaaat tataaaaagt atctcaatgt aaattttgaa
     1921 agttataaag gagatacttt tttattttgt aaatatggag tatcctactt ataagtatta
     1981 agctatatag atattgatga ttagctatgc aataaaaaag agtatgtgtt tttgcattta
     2041 tacatcataa c
//
LOCUS       DAEPKC010000202         2047 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.206, whole genome shotgun sequence.
ACCESSION   DAEPKC010000202 DAEPKC010000000
VERSION     DAEPKC010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2047)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2047)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2047
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.206"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     misc_binding    785..1048
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            1199..1750
                     /locus_tag="KR294_003705"
     CDS             1199..1750
                     /locus_tag="KR294_003705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan transporter"
                     /protein_id="HBH0241745.1"
                     /translation="MKTNTKKLTLNAILLAMGLLIHQITPAIGLPMKPDVPLAMLFVI
                     LVLNRDDYKTCLIAGIVTGIFTALTSSFPGGQIPNVIDKTLTANIVFLLMNISYNMPF
                     IKKLAKKTQDTVVVAIIMPIGTLVSGTIFLLAAQAIVGLPGASFTALFLAVVLPAVLI
                     NLVAGIFLFKIVSLSIRRVSYQA"
BASE COUNT          852 a          199 c          289 g          707 t
ORIGIN      
        1 taatcagcat tataaatcca ttacaagtag aagcagaagc tattattgag tctagtgtat
       61 acatttcttc aataaaagag aattatacat atgataatac taaatttaaa actattaaat
      121 ctaaaagtag acataaaagt aggaaatata ataaaagtaa agtaaagttg aaaaaacgaa
      181 gtataagaac taaaaagtat ggatatcaaa ctataaataa atataaaaga caaaacgcaa
      241 gaagacataa tatcctaaca aaattaatat tgttcataat agtcatattt ttggttatag
      301 ttttagtagt gctaatattt attaaaagaa agaagaaaaa attttactaa aaataattaa
      361 aagaatatca tttttttaat cattggtatc tatttaataa tatgatgtaa ttaaaatgga
      421 gtaatattct gtttcaaagg aggcatataa atacaggaat gagtattaaa tgatggttaa
      481 ttaagtaaat ttattgataa atgtacttaa ttaactttga agaatttaat tcctcatgaa
      541 tcaaaatata aaattacatc aacagttatt cacaaaatta atataagaag aattagagcc
      601 aaagagcaga ctattagacc attaaagtaa ttattcatag aattttgtat atgaaaagaa
      661 atgtatagta taatttactt tttttataaa aaatagatta caaaatatat tttttataaa
      721 aaggtattga cattttttag aaaaaagaat attattattt taaaacaaaa ttcaatacaa
      781 taaattaaat cctatgacaa ggaagagtag ttaaatttag gttcagtata gagagctgag
      841 gatggtggaa tcttagcaag aaaaaatttg atgaatggcc cttagaggaa taaattgaaa
      901 tcatagtttt gagagtagac tttatcgtca gtcgcacgtt atagcgaata aggtatgtaa
      961 gtacctgata atgagatgta tgaaaattga attttatatt aatttttata taatttaggt
     1021 ggcaacgcgg ataatctccg tcctattagt ttaggacgga gttttttatt ttactgaaaa
     1081 tttaaaagat agaaggtggt gagaaagatg ttatgaattt caaaagctaa agatgatgat
     1141 atagtaggtt ggcaaaaaaa taaattgaaa attaaaaaaa taggaggaag tacaaaaaat
     1201 gaaaacaaat acaaaaaaat taactttaaa tgcaatactt ttagcgatgg gattattaat
     1261 acatcaaatc acaccagcta taggattacc aatgaagcca gatgtaccac tagcaatgtt
     1321 atttgtaata ttggttttaa atagagatga ttataaaact tgtttgatag cgggtatagt
     1381 aacaggaata tttacagcac ttacatcaag ttttccggga ggtcaaattc ctaatgtaat
     1441 agataaaact cttacagcaa atatagtatt tttattaatg aatattagtt ataatatgcc
     1501 ttttataaaa aaattagcta agaaaacaca agatactgta gtagttgcaa taataatgcc
     1561 aataggaact cttgtaagtg gaactatctt tttattagca gctcaagcta tagttggtct
     1621 tccaggggct tcatttacag ctttattctt agcagtagta ttaccagctg ttttaataaa
     1681 tctagttgca ggaatatttt tattcaagat tgttagtcta tcaataagaa gagttagtta
     1741 tcaagcttaa acacgaaata atattttact ttataaagca ttataataac taaataacat
     1801 aagaataaag tagattataa ctattttatt cttatgttgt ttaaagattt ggtattatat
     1861 atttattttt aataaaatat ttatatagta ccaattacac ttaatttaac agataaatta
     1921 tcatacctat ataatattct tatatgtatc tcatttgtag ttattaaata taagatatat
     1981 ttaattgact tttcaagata aatttttata ttaatctcct ctgatttctc attttttgaa
     2041 tacacta
//
LOCUS       DAEPKC010000203         1995 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.207, whole genome shotgun sequence.
ACCESSION   DAEPKC010000203 DAEPKC010000000
VERSION     DAEPKC010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1995)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1995)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1995
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.207"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            220..834
                     /locus_tag="KR294_003706"
     CDS             220..834
                     /locus_tag="KR294_003706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HBH0241746.1"
                     /translation="MEEVIAKIITIENGFKEIENIAKKIVKNNDSKKCYYLSIYLYRS
                     EYYQVRELAVFILGFISVTISEALLFLKDNVSKDENWRVQEILAKSFDYYCSEVGYEK
                     ALPVIKEWLNSDSPNIKRAVTEGLRIWTNRDYFKSNPDVAISLLSSLKEDDSEYLRKS
                     VGNALRDISKKYPDLVKKELDSWDISNKKVEFVYKLASKCILAK"
     gene            852..1214
                     /locus_tag="KR294_003707"
     CDS             852..1214
                     /locus_tag="KR294_003707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0241747.1"
                     /translation="MKLRDEYTCPLELTHDMIKGKWKSIILWRLRIGPTSLSKLEKEI
                     NGINQKMLLEQLKELIEFGLVDKKTYEGYPLKVEYSLTPIRGKQILDALAIMQDIGIS
                     FMLDNGMEDILKEKGVLK"
     gene            1320..1817
                     /locus_tag="KR294_003708"
     CDS             1320..1817
                     /locus_tag="KR294_003708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbhB/YbcL family Raf kinase inhibitor-like
                     protein"
                     /protein_id="HBH0241748.1"
                     /translation="MKVTSTGIVNGVIEDKYGKRGTQFNEGGMPTYSLPLKFEDAPKN
                     TVSFAVFLEDKDSVPVCGFAWIHWLAVNITKDELNENESVTATDFVQGTTSWHGKLGG
                     LDRLEASVYGGMAPPDRPHVYEIHVFALDTILDLEKGFYMNEFFKAIEGHVLDTFTLK
                     GSYSN"
BASE COUNT          762 a          220 c          332 g          681 t
ORIGIN      
        1 ctcaattaat tttttaaata caactttata atataaaact tataataaaa gtaaatttat
       61 atgttaaatg aggttgattt tttattattt tttatttatg ctagtactaa agacttgcaa
      121 acgttttttg acaagtcttt attttgtcta aattaaacaa acttttttac aaataaatac
      181 ataaaattta aactaatcta tttattggag gagataaaat tggaagaagt aattgcaaaa
      241 attattacta tagaaaatgg attcaaagaa attgaaaaca ttgctaaaaa aattgtaaaa
      301 aataatgact caaaaaagtg ttattatcta tcaatctact tatataggtc agaatattat
      361 caagtaagag aattggctgt gtttatactt ggttttatat cagtaactat ttctgaagct
      421 ttgttatttt taaaagataa tgtgagtaaa gatgaaaact ggagagtaca agaaatacta
      481 gctaaatcat ttgattatta ttgcagtgaa gtaggatatg aaaaggcact tcctgttata
      541 aaagaatggc ttaattctga tagtccaaac ataaaaaggg ctgtgacaga aggtcttcga
      601 atttggacta atagagacta ttttaaatct aatcctgacg ttgctatatc actactttct
      661 agtttaaaag aagatgatag cgaatacttg agaaagtctg taggtaatgc tcttagagat
      721 ataagtaaaa aatatccaga tttagtaaaa aaagaattag attcatggga tatatcaaat
      781 aaaaaagttg agtttgtata taagcttgct tcaaaatgta tcttggcaaa gtaaaatgga
      841 ggtgaactta tttgaaactt cgtgatgagt atacttgccc attagaacta acacatgata
      901 tgataaaagg caaatggaaa tctattatat tatggagatt acgcatagga ccaacttcct
      961 tatcaaaact tgaaaaggaa atcaatggta ttaatcaaaa gatgttactt gaacaactta
     1021 aagaattaat tgaatttggt cttgtagata aaaagacata tgaaggttac ccacttaaag
     1081 tcgaatactc acttacacct attcgaggga aacaaatatt ggatgctttg gctataatgc
     1141 aagatatagg aattagcttt atgttggata atggtatgga agatattctt aaggaaaaag
     1201 gtgttttaaa ataaatagat acccacaaaa aagtaagtaa tttaccatta ttttcaactg
     1261 gtatataatt aaattataga tatattctat taatttatta taataggagg taaattatta
     1321 tgaaagtaac tagtacaggt atagtaaatg gtgttataga agataaatat ggtaaaagag
     1381 gaactcagtt caatgaaggt ggtatgccta catattcact acctctaaag tttgaagatg
     1441 ctccaaagaa tacagtatcc tttgctgtat ttttagaaga taaagactct gttcctgtat
     1501 gtgggtttgc atggatacat tggttagctg taaatataac aaaagatgag ttaaatgaaa
     1561 atgaaagtgt aacagctact gattttgtac aagggactac tagttggcat ggtaaactag
     1621 gaggtcttga cagattagag gccagtgtat atggtggaat ggctcctcca gacagacctc
     1681 atgtctatga aatacatgta tttgcacttg atactatcct tgaccttgaa aaaggattct
     1741 atatgaatga atttttcaaa gctattgaag ggcatgtttt agatacattt acactaaaag
     1801 gaagttattc taattaatta ggttgactat agctaatcat taattaaatg atacatttaa
     1861 ttgatgatta gcttaattgt tattagaata ttttctgcac tttatcttaa tatatatttt
     1921 agttgactgg tattttaatt tctattagat tattatcaat ttatataaat tgattaaaaa
     1981 atagctacgc acact
//
LOCUS       DAEPKC010000204         1990 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.208, whole genome shotgun sequence.
ACCESSION   DAEPKC010000204 DAEPKC010000000
VERSION     DAEPKC010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1990)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1990)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1990
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.208"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..196
                     /locus_tag="KR294_003709"
     rRNA            <1..196
                     /locus_tag="KR294_003709"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            324..440
                     /gene="rrf"
                     /locus_tag="KR294_003710"
     rRNA            324..440
                     /gene="rrf"
                     /locus_tag="KR294_003710"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            448..522
                     /locus_tag="KR294_003711"
     tRNA            448..522
                     /locus_tag="KR294_003711"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:480..482,aa:Asn,seq:gtt)
     gene            528..613
                     /locus_tag="KR294_003712"
     tRNA            528..613
                     /locus_tag="KR294_003712"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:562..564,aa:Leu,seq:taa)
     gene            629..704
                     /locus_tag="KR294_003713"
     tRNA            629..704
                     /locus_tag="KR294_003713"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:662..664,aa:Met,seq:cat)
     gene            712..786
                     /locus_tag="KR294_003714"
     tRNA            712..786
                     /locus_tag="KR294_003714"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:745..747,aa:Glu,seq:ttc)
     gene            801..874
                     /locus_tag="KR294_003715"
     tRNA            801..874
                     /locus_tag="KR294_003715"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:833..835,aa:Gly,seq:tcc)
     gene            880..955
                     /locus_tag="KR294_003716"
     tRNA            880..955
                     /locus_tag="KR294_003716"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:913..915,aa:Val,seq:tac)
     gene            961..1037
                     /locus_tag="KR294_003717"
     tRNA            961..1037
                     /locus_tag="KR294_003717"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:995..997,aa:Asp,seq:gtc)
     gene            1048..1122
                     /locus_tag="KR294_003718"
     tRNA            1048..1122
                     /locus_tag="KR294_003718"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1080..1082,aa:Gly,seq:gcc)
     gene            1132..1205
                     /locus_tag="KR294_003719"
     tRNA            1132..1205
                     /locus_tag="KR294_003719"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1166..1168,aa:Arg,seq:tct)
BASE COUNT          635 a          331 c          420 g          604 t
ORIGIN      
        1 ctgccaaggg catggctggg tagctatgta cggaatggat aagcgctgaa agcatctaag
       61 cgcgaagcca acttcaagat aagatttccc accgcaaggg taagacccca gaaagactat
      121 ctggttgata ggtcgaaggt gtaagtgcag caatgtattt agcttatcga tactaatagg
      181 tcgaggactt gaccaatatt tatttgatgt tcattcatta agatatatgt gtagttttta
      241 gagtgctaac tctaaagaaa ctagtattgc taggttctat aaacttatta aaaacttaat
      301 agaaatatta agcataaaga ttatgtggtt acaatagcag agaggataca cctgttccca
      361 tttcgaacac agaagttaag ctccctagcg ctgatggtac ttggtgggaa actgcctggg
      421 agagtaggac gtagccacgt taaatgttcc aaggtagctc aacggtggag caaccggctg
      481 ttaaccggta ggctgtgggt tcgagcccca cccttggagc caaaaaagcc gaagtggcgg
      541 aactggcaga cgcacaggac ttaaaatcct gcgggactta cctctcgtac cggttcgatt
      601 ccggtcttcg gcacttataa aacaatatcg cggggtggag cagttggcag ctcgtcgggc
      661 tcataacccg aaggtcgtag gttcaagtcc tgcctccgca accattaaaa cggctcgttg
      721 gtcaagaggt taagacaccg ccctttcacg gcggtaacag gggttcaatt cccctacgag
      781 tcaccaattc aattaaatat gcgggtgtag ctcaatggta gagttctggc cttccaagcc
      841 agctgtgagg gttcgatccc cttcacccgc tccaaaaatg ggaccatagc tcagctggga
      901 gagcacctgc cttacaagca gggggtcaca ggttcgagcc ctgttggtcc caccattcgc
      961 ggcctggtag ttcagttggt tagaatgcca gcctgtcacg ctggaggtcg agggttcgag
     1021 ccccttccag gtcgccaaat taaataagcg ggaatagttc agtggtagag cgcaaccttg
     1081 ccaaggttga agtcgcgagt tcgaatctcg tttcccgctc cataataact tgggtgcata
     1141 gctcagctgg atagagcaac gcccttctaa ggcgtgtgtc cggggttcga atccctgtgc
     1201 gctcattaag aaaagtttac tataaattat agtaaacttt tatattgttt aaaaagacac
     1261 aggaaacatg tatattacct gtgtcttttt atttataaac tttaaactat gtaaaaatta
     1321 cagtatattc taatagagtt acagtatatt cattaatatt gtaaacatac ggagggtaat
     1381 gtataatagt ctacaagatg tttatgaagg catcagttaa atataataaa tataactaat
     1441 tagtaagagt tatatacatt atattgtata ctttatggta tttatatatt gaaataactt
     1501 atgaaattat ttataaagag attcatgagc atatttttgt ctaaacaata agtataagaa
     1561 attataaaaa gttagagact atagtgaatt tacaatttaa tgtaatattt ataagttata
     1621 ctaaataaat tattatactg tgaaatggat atataacttt aggtattgtg tattattttc
     1681 actgtaggag attatatcta gttatacata ataagtttta atgatagttt atagtaagat
     1741 attaaaataa atttatctaa tctagatatg aaataagtta ttactttaat ataaaaatga
     1801 atctaatgga ataatattga tgataagtaa tatttagatt ttgtatttgt ttatagttaa
     1861 taagtggatt atagaattta taataattaa tatatattaa acaaagatat attaagatat
     1921 tttagaacat aaaactgaat taaggcgcga gtactatttt gtattcgcgc cttgatggtt
     1981 tgagttattt
//
LOCUS       DAEPKC010000205         1986 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.209, whole genome shotgun sequence.
ACCESSION   DAEPKC010000205 DAEPKC010000000
VERSION     DAEPKC010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1986)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1986)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1986
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.209"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            84..200
                     /gene="rrf"
                     /locus_tag="KR294_003720"
     rRNA            84..200
                     /gene="rrf"
                     /locus_tag="KR294_003720"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            207..281
                     /locus_tag="KR294_003721"
     tRNA            207..281
                     /locus_tag="KR294_003721"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:239..241,aa:Asn,seq:gtt)
     gene            286..360
                     /locus_tag="KR294_003722"
     tRNA            286..360
                     /locus_tag="KR294_003722"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:319..321,aa:Glu,seq:ttc)
     gene            366..441
                     /locus_tag="KR294_003723"
     tRNA            366..441
                     /locus_tag="KR294_003723"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:399..401,aa:Val,seq:tac)
     gene            447..523
                     /locus_tag="KR294_003724"
     tRNA            447..523
                     /locus_tag="KR294_003724"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:481..483,aa:Asp,seq:gtc)
     gene            534..608
                     /locus_tag="KR294_003725"
     tRNA            534..608
                     /locus_tag="KR294_003725"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:566..568,aa:Thr,seq:tgt)
     gene            623..707
                     /locus_tag="KR294_003726"
     tRNA            623..707
                     /locus_tag="KR294_003726"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:657..659,aa:Tyr,seq:gta)
     gene            717..790
                     /locus_tag="KR294_003727"
     tRNA            717..790
                     /locus_tag="KR294_003727"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:749..751,aa:Gly,seq:tcc)
     gene            801..877
                     /locus_tag="KR294_003728"
     tRNA            801..877
                     /locus_tag="KR294_003728"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:835..837,aa:Arg,seq:tct)
     gene            887..962
                     /locus_tag="KR294_003729"
     tRNA            887..962
                     /locus_tag="KR294_003729"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:920..922,aa:Gln,seq:ttg)
     gene            974..1049
                     /locus_tag="KR294_003730"
     tRNA            974..1049
                     /locus_tag="KR294_003730"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1007..1009,aa:Lys,seq:ttt)
     gene            1052..1140
                     /locus_tag="KR294_003731"
     tRNA            1052..1140
                     /locus_tag="KR294_003731"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1086..1088,aa:Ser,seq:tga)
     gene            1158..1248
                     /locus_tag="KR294_003732"
     tRNA            1158..1248
                     /locus_tag="KR294_003732"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1192..1194,aa:Ser,seq:gct)
     gene            1257..1333
                     /locus_tag="KR294_003733"
     tRNA            1257..1333
                     /locus_tag="KR294_003733"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1291..1293,aa:Pro,seq:tgg)
     gene            1419..1494
                     /locus_tag="KR294_003734"
     tRNA            1419..1494
                     /locus_tag="KR294_003734"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1452..1454,aa:Trp,seq:cca)
     gene            1555..1631
                     /locus_tag="KR294_003735"
     tRNA            1555..1631
                     /locus_tag="KR294_003735"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1589..1591,aa:Pro,seq:tgg)
     gene            1638..1714
                     /locus_tag="KR294_003736"
     tRNA            1638..1714
                     /locus_tag="KR294_003736"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1672..1674,aa:Ile,seq:gat)
     gene            1718..1793
                     /locus_tag="KR294_003737"
     tRNA            1718..1793
                     /locus_tag="KR294_003737"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1751..1753,aa:Phe,seq:gaa)
     gene            1801..1877
                     /locus_tag="KR294_003738"
     tRNA            1801..1877
                     /locus_tag="KR294_003738"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1835..1837,aa:Met,seq:cat)
BASE COUNT          517 a          452 c          531 g          486 t
ORIGIN      
        1 taactctaaa aaaaaataaa aaaagtattg acaaaaatag taaaaaatgt taatattata
       61 cttgtcctag caacaagaaa aaatgtggtt ataatagcgg aggagataca cctgtttcca
      121 ttccgaacac agaagttaag ttctctagcg ctgatggtac ttggtgggaa actgcctggg
      181 agagtaggac atagccacgt gaatgttcca aggtagctca acggtggagc aaccggctgt
      241 taaccggtag gctgtgggtt cgagccccac ccttggagcc attatggctc gttggtcaag
      301 aggttaagac accgcccttt cacggcggta acaggggttc aattccccta cgagtcacca
      361 tttgtgggat catagctcag ctgggagagc acctgcctta caagcagggg gtcacaggtt
      421 cgagccctgt tggtcccacc atttgcggcc tggtagttca gttggttaga atgccagcct
      481 gtcacgctgg aggtcgaggg ttcgagcccc ttccaggtcg ccaaaataaa aatgctggtg
      541 tggctcaacg gtagagcagc tgacttgtaa tcagcaggtt gtaggttcga ttcctatcac
      601 cagctccatg taaaactaat acggaggatt tcccgagcgg ccaaaggggg cagactgtaa
      661 atctgttgtc atcgacttcg gtggttcgaa tccaccatcc tccaccaatt aaatatgcgg
      721 gtgtagctca atggtagagt tctggccttc caagccagct gtgagggttc gatccccttc
      781 acccgctcca aagaaagcgt gggtgcatag ctcagctgga tagagcaacg cccttctaag
      841 gcgtgtgtcc ggggttcgaa tccctgtgcg ctcaccacat atatattggg gattagccaa
      901 gtcggtaagg cacatgactt tgactcatgt atgcgtaggt tcgagtcctg catccccagc
      961 caaataaaaa tatggtctat tagctcagtc ggtagagcac ctgactttta atcagggtgt
     1021 cccgcgttcg agtcgcggat agatcaccaa tggagaggtg tccgagtggt ttaaggagct
     1081 ggtcttgaaa accagtgact tcgaaagggg ccgtgggttc gaatcccacc ctctccgcca
     1141 aaaaaatgac tgaatttgga gaagtactca agtggctcaa gaggatcccc tgctaaggga
     1201 ttaggctggg taaccggtgc gagggttcga atccctcctt ctccgccatt caaaaacgag
     1261 gtgtagcgca gtttggtagc gcacatggtt tgggaccatg gggccggggg ttcgagtccc
     1321 ttcacctcga ccaacttaag cttttagttc agttggttag agtgcccaac tcatggctag
     1381 taattctagg gtttgagtcc atgaaggtta ttcttcatag gggtgtagct cagttggtag
     1441 agcgtcggtc tccaaaaccg tgcgccgggg gttcgagtcc ctccacccct gccaaataaa
     1501 aaggacttga aaaaagttgg attttagagt agtataagat agtaaataag atttcgaggt
     1561 gtagcgcagt ttggtagcgc acatggtttg ggaccatggg gccgggggtt cgagtccctt
     1621 cacctcgacc aagaaaaggg cctatagctc aggtggttag agcgcacgcc tgataagcgt
     1681 gaggtcgctg gttcgagtcc agctaggccc accatttgcc cagatagctc agtcggtaga
     1741 gcaggggact gaaaatcccc gtgtcggtgg ttcgattccg cctctgggca ccaggaatac
     1801 ggcggtatag cttagttggc tagagcgttc ggttcatacc cgaaaggtca taggttcgac
     1861 tcctattacc gctaccatct aactatatca ataaagaact ttgaaaatta aacagtaggt
     1921 taatttataa acaagaaaca aaccataaag ccagatattt tgataacaat agtatctgag
     1981 cctgat
//
LOCUS       DAEPKC010000206         1915 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.210, whole genome shotgun sequence.
ACCESSION   DAEPKC010000206 DAEPKC010000000
VERSION     DAEPKC010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1915)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1915)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1915
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.210"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            432..899
                     /locus_tag="KR294_003739"
     CDS             432..899
                     /locus_tag="KR294_003739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBH0241749.1"
                     /translation="MKFLNVLIVVEDIEKSKKFYYDVLGLKVICDFGENVVLEGNISL
                     QEKKLWLEFINKSDSEVKFNGNDAELYFEEDYFDTFVERLSTMRDIDYVHLAIEHRWG
                     QRAIRFYDLDGHIIEVGETMSSVCRRFLDSGLSIDEVAKRMDVTVEYIESVLE"
BASE COUNT          790 a          114 c          269 g          742 t
ORIGIN      
        1 aataattaga aagattatga aaactaaatt agaagaacta aaaactatat ttttattaat
       61 tagaatattt gaataatctc tttaatcata taaaatacat atgcttgtaa tatttaaagg
      121 tgatattaat attattagtg tatattaata ttctcttgaa attaaaaaaa catagatatt
      181 tcagtaatct aaaatagtct acaaaaataa cagttttagc aaaattaata agaatacata
      241 tagatttaaa cctaaaagta tgaatgtgtc tgttttttac aagattaaaa tttatattat
      301 atgatacaat taacttaact atttcaataa gacttataat ttttttcttt atactagacc
      361 ttattgaaac ctttatagtt taattctaat tatatattat aaataaagta tgtgtatatt
      421 aaggaggtaa tatgaagttt ttaaatgttt taatagtagt tgaagatatt gagaaatcaa
      481 aaaagtttta ttatgatgtt ttggggttaa aggtaatctg tgattttgga gaaaatgttg
      541 tattagaagg gaatatatca ttacaagaaa aaaagctttg gttagagttt attaataaga
      601 gtgacagtga agttaagttc aatggaaatg atgctgagct gtattttgag gaagattatt
      661 ttgatacttt tgttgaaaga ttgagtacaa tgagagatat agattatgtt catctagcta
      721 tagagcatag gtggggtcaa agagcaatta gattttatga tttagatggg catattattg
      781 aggttggaga aactatgtca tctgtgtgta gacgtttttt agatagtggt ctttcaatag
      841 atgaggtagc taaaagaatg gatgtaactg tcgaatatat tgaatcagtt ttagaataga
      901 tggattatat taaagtaaaa ctatattttg tatagaagta agggctgtaa gtaaacttgt
      961 atggaaacaa atttacttac agtttttgtt tttgtaagat acagaatata atatttgtta
     1021 taattttatt tggattttta aaaagtgcat gattttcctt acatattata atagaattta
     1081 atatttattg gatgatttaa atttagaaaa atataagtat tagcttataa aagataatta
     1141 tacttactat caagctgtag aatcatatat actattttat gtaattatgt taaaatttaa
     1201 ttgaacaaat taaaaatata gtgaaaattg tagttttagt ttatttattt aataaatatt
     1261 tcaaataaaa taatgtttaa ataagaaaca taaataataa tattattatt gttcttaaag
     1321 acaaaaaatc ttagcttaaa aatttgtatc atataaaatc cctacatatt atggaagtaa
     1381 tgatacatta tatgatatac acaataaagt ataaaagtat ttacatgttt tttctatata
     1441 ttttataagt tttaggtatg gaaaattact aaataaaaat tagattaatg attatgatag
     1501 tatagataaa gtttattctt tttattaata gaaattgttg tataaaaata ataaaagtga
     1561 ggagagtgat atttaaataa aaaaatttta ataagtattg gtaatatagt ttttagggat
     1621 gattatttta tgtaaaaagt tgttatttgt aaagataaat atagaaaata ttataagtat
     1681 tgatttagtg ataatctaaa aggtgagaat tgtaataaaa agagaacata tccttcaaat
     1741 ggatgtaaac ttataaataa cattattaca agagatttat tatacatata ctgcaactat
     1801 taattagaat ttatactgta tttgtattta aataaaaaca caaataatat tattgtaaaa
     1861 atttataatt attaaatatt taaagtataa gatataataa ttataagtaa tttat
//
LOCUS       DAEPKC010000207         1805 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.211, whole genome shotgun sequence.
ACCESSION   DAEPKC010000207 DAEPKC010000000
VERSION     DAEPKC010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1805)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1805)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1805
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.211"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(<1..92)
                     /locus_tag="KR294_003740"
     CDS             complement(<1..92)
                     /locus_tag="KR294_003740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011058338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241750.1"
                     /translation="MKDKWILCPVCGNKTRLKIRADTELKNFPL"
     gene            complement(131..418)
                     /locus_tag="KR294_003741"
     CDS             complement(131..418)
                     /locus_tag="KR294_003741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015574378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241751.1"
                     /translation="MSTLIIGFIVAGVLLIAEYLLCTKFRSPLWGGIIPLLILAGTIY
                     VFASGRIPFERPYIFPFVVVNTLFFGDWGTGRDKYKKIKQTEMEKMKAKDI"
     gene            complement(421..717)
                     /locus_tag="KR294_003742"
     CDS             complement(421..717)
                     /locus_tag="KR294_003742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009460866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2089 family protein"
                     /protein_id="HBH0241752.1"
                     /translation="MELDKIPQWILALEQEDATFLKNFALKSGSLKEIAKMYGVSYPT
                     VRLRLDKLIQKIEMCDQQEEEPFQTFIKGLAVDSRIDVETAKIIIEKYKKEKEK"
     gene            complement(806..1711)
                     /locus_tag="KR294_003743"
     CDS             complement(806..1711)
                     /locus_tag="KR294_003743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBH0241753.1"
                     /translation="MFKKNKKQTENVKEKKVRTVKVGTHKKSVIALWVVLIASVSFGV
                     YKNFTAIDMHTVHETETIQLRLTDTNGIENFVKNFAKSYYTWNNSKEAIEARTQAISG
                     YLTKELQALNTDTIRKDIPVSSAVNGVQIWSVTQADENQFSVIFTVEQLITENGSTKT
                     VRSAYEVTVYVDGSGNMVLTKNPTITSIPVKSGYTPKAKESDGTVDAVTTDEINEFLT
                     TFFKLYPTATAKELSYYVNEGVLKPIGKDYVFSELVNPIYNRIDSQVTVSVAVKYLDQ
                     QTKATQVSQFDLVLEKSGSNWKIIK"
BASE COUNT          485 a          397 c          300 g          623 t
ORIGIN      
        1 aatagtggga aatttttaag ctctgtgtcc gctctaattt tcaacctcgt tttattaccg
       61 caaactggac ataaaatcca tttatctttc aataatgcgt tcctcctatc taagtataca
      121 gttttgtaat ttatatatct ttagctttca tcttttccat ttcagtttgc tttatctttt
      181 tatatttatc cctgccagta ccccaatctc caaaaaataa agtattgact acaacaaacg
      241 ggaaaatata tggtctttca aatggtattc tgccacttgc aaaaacatat attgttcctg
      301 ccaagataag caagggaata atacctcccc aaagaggact tctaaatttt gtgcagagaa
      361 gatactctgc aattaataaa actcctgcaa caataaagcc aataattaat gtactcatgg
      421 ttatttctcc ttttcttttt tatatttttc aataattatc tttgcagttt ccacgtcaat
      481 tcgagaatca accgctaacc ctttaataaa agtttggaaa ggttcttctt cctgctggtc
      541 gcacatttca attttttgaa ttaatttgtc taaacgtaat cgaacagtag ggtaagatac
      601 cccatacatt ttcgctattt cctttaatga accggattta agtgcgaagt ttttaagaaa
      661 agtagcgtcc tcttgctcta aggcaagaat ccattgaggg attttatcaa gctccaaaaa
      721 cacaactcct ttcatattat ctttaacaat attcagtata tcataaataa aattaaagtc
      781 aataagaatt taaacatcaa aataattatt ttataatctt ccagttgctc ccgctttttt
      841 ccagcaccaa atcaaattgt gatacctgcg ttgcctttgt ctgctggtcg aggtacttca
      901 cagccacgga aaccgtcact tgactgtcga tgcggttgta gatgggattt accagttccg
      961 agaatacata atctttcccg ataggcttta acacgccctc atttacataa taggacagct
     1021 ctttagcggt tgcggttggg tagagcttaa agaacgtcgt cagaaattcg ttgatttcgt
     1081 ccgtcgtcac agcgtccacc gttccgtcgc tttcctttgc ctttggcgtg tagccggatt
     1141 tcacgggtat gctggtaatg gtcggattct tcgtgagaac catgtttcca gagccatcca
     1201 catagaccgt gacttcatag gcggagcgta ccgtcttcgt gcttccattc tccgtgatta
     1261 actgttccac agtgaagatc acggagaact ggttttcatc cgcctgcgtg acagaccata
     1321 tctgtacccc attgaccgcc gaagacactg gaatatcctt gcggatggta tcggtattaa
     1381 gtgcctgcaa ttcctttgtc agataaccgc tgattgcctg cgtccttgct tcaatagctt
     1441 ctttgctgtt attccatgtg taataggact tcgcaaagtt cttcacgaaa ttttcaatcc
     1501 cgttggtatc ggtaagtctt aactgtatgg tttctgtttc atgtacggtg tgcatatcaa
     1561 tagcggtaaa attcttatat accccaaaac tcacgcttgc gataagcact acccacaatg
     1621 caatcacaga ttttttatgt gtaccgactt tcacagtacg cactttcttt tctttgacat
     1681 tctctgtctg tttcttattc ttcttaaaca tattttctaa gtcctttctt ttattttact
     1741 cgtcctgcac cgattaagtg ttgttgccag taactattat ttaagtctgc atatcctatc
     1801 ggatt
//
LOCUS       DAEPKC010000208         1744 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.212, whole genome shotgun sequence.
ACCESSION   DAEPKC010000208 DAEPKC010000000
VERSION     DAEPKC010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1744)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1744)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1744
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.212"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(<1..600)
                     /locus_tag="KR294_003744"
     CDS             complement(<1..600)
                     /locus_tag="KR294_003744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HBH0241754.1"
                     /translation="MEELKDFLERQLNKKINIYPYENQKLDASSHLVTFNNAIYVIDF
                     LDKNNLDNLKGNFYLIYQSHIDFEYLKNIFYNLFEDINIIQHNGFFIVNSKYNLDINV
                     TTQNIIETETYQSTYIFYLGELDSKADFDFRLQLCSDLLPHIIKDNAENKFLNLFDLI
                     RYKTLDLINEDNILNKLIDFNKIKSIDEELLYTGIKFINN"
     gene            complement(630..1739)
                     /gene="ugpC"
                     /locus_tag="KR294_003745"
     CDS             complement(630..1739)
                     /gene="ugpC"
                     /locus_tag="KR294_003745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003242648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HBH0241755.1"
                     /translation="MSEVILKNISKLYSNGFNAVKNINIDIKDKEFIVLVGPSGCGKS
                     TTLRMIAGLEEISEGELYIGDKLVNDIEPKDRDIAMVFQNYALYPHLSVYENMAFALK
                     LRKLPKDEIDKKVKEAAKILDLLPLLNKKPKTLSGGQRQRVALGRAIVRNPKVFLMDE
                     PLSNLDAKLRTAMRTEITKLHQQLGTTFIYVTHDQVEAMTMADRIVVMKDGVVQQIAT
                     PQDVYDYPANIFVAGFIGAPQMNFIDVILIEENDEIYAQNEHIKLKLNKEKHYDLIKD
                     NYINNEVVIGIRPEDIHVEDTFIKSNPDTCFKSRIEIKELMGAETYAHLKLGENTITI
                     RFDSKNRINVGDDLTLSVDNSRVHIFDKETTLAIR"
BASE COUNT          569 a          251 c          209 g          715 t
ORIGIN      
        1 attatttata aattttattc ctgtatatag aagttcttcg tcaatagatt taatcttatt
       61 aaaatctatt aatttattga gtatattatc ctcattaatt aaatctaaag ttttatatct
      121 aataaggtca aacaaattta aaaacttatt ttcagcgttg tcttttataa tatgaggtag
      181 taaatcagaa cataactgta atctaaaatc aaaatcagct ttactatcta attcaccaag
      241 ataaaaaata taagtacttt gataagtttc agtttcaatt atattttgtg tagttacatt
      301 aatatctaag ttatatttag aatttactat aaaaaaacca ttgtgttgta ttatatttat
      361 atcttcaaat aaattataaa aaatattttt tagatattca aagtctatat gagattggta
      421 aattaaataa aagttgcctt ttaaattatc gagattattt ttatctagaa aatcaataac
      481 ataaatagca ttattgaaag taactaaatg gctactagca tctaactttt ggttttcata
      541 tggatagata tttatttttt tattaagctg tctttctaaa aaatctttta actcttccat
      601 aaagtctcct taaaaataag attatattct tatcttatag ctaaagtagt ttctttgtca
      661 aatatgtgta ctctactatt gtcaactgaa agtgttaagt catcaccaac attaattctg
      721 tttttactgt caaatctaat tgttatcgta ttttcgccta gttttaagtg agcataagtt
      781 tctgctccca taagttcttt tatttcaatt cttgatttaa aacaagtatc tggattagat
      841 ttaataaaag tatcttctac atgaatatct tctggtctga tacctataac aacttcatta
      901 ttaatataat tgtcttttat taaatcatag tgtttttctt tattcaattt aagcttaata
      961 tgttcatttt gtgcataaat ttcatcattt tcttctatta atattacatc aataaaattc
     1021 atctgtggtg ctccaataaa tcctgcaaca aatatattag ctggataatc gtatacatct
     1081 tgtggagttg caatctgctg aactactcca tccttcatta ctacgattct atcagccata
     1141 gtcatagctt caacttggtc gtgtgttaca tagataaatg tagttccaag ctgttggtgt
     1201 agcttagtta tctctgttct catagcagtt ctaagttttg catctaagtt ggatagaggt
     1261 tcatccatta agaatacctt aggatttcta actattgcac gtcctaaggc aaccctttgt
     1321 ctttgtcctc cagataatgt tttaggtttt ttatttaaaa gaggtagtaa gtctaatatt
     1381 ttagcagctt ctttaacttt tttgtctatt tcatctttag gcaattttct aagtttaagt
     1441 gcaaatgcca tgttttcgta aacagataag tggggatata aagcatagtt ttgaaaaacc
     1501 atagctatat ctctatcttt tggttctata tcattgacaa gtttatctcc aatgtatagt
     1561 tctccttcag agatttcttc aagaccagca atcattctaa gtgtagtcga tttaccacaa
     1621 ccagatggtc ctactaaaac gataaattct ttatctttaa tgtctatatt tatatttttt
     1681 actgcattaa atccatttga gtaaagtttt gatatatttt ttaaaattac ttctgacata
     1741 atat
//
LOCUS       DAEPKC010000209         1493 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.214, whole genome shotgun sequence.
ACCESSION   DAEPKC010000209 DAEPKC010000000
VERSION     DAEPKC010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1493)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1493)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1493
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.214"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            552..>1493
                     /locus_tag="KR294_003746"
     CDS             552..>1493
                     /locus_tag="KR294_003746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HBH0241756.1"
                     /translation="MSNKQGSNIKDVKIKNKLIILKLLSTNTPMSRVDLAKSTGLTKM
                     TLSNLVTELINENMIREIESSTLNAHSSGRKPILLDISNISPCICGILIRRNICKVII
                     SDLKGNIVKQLSETYPKCLSNDVLKDIIKRMFTKIMKINKRDIIGIGISSIGPVDDIN
                     GTILNPPDFGNVSNLNIVDFIKEMSDLPIFLINDANSGALAEKMYGLGKNISNYIYLH
                     IMNGIGAGLVLENKLHTGNLGQSGEIGHTSINFSGPLCSCGNNGCLDYYTSVSNLIKR
                     IESLSHIYPNSPLINCKDFSLVKLIDEANNKDSLAMFL"
BASE COUNT          580 a          170 c          192 g          551 t
ORIGIN      
        1 aagtttccat aatattgtat agattaaagg aaaaatttac attttagtta caatttacta
       61 gatttttgtt ctaatgtacc tatatttagt aacaatttgt aataaaaatc gatatctata
      121 ttacatattt aattcactgt tttacaaaat gaaattttat tgtatacaat aaatagatta
      181 tatgtttaca taatctatat tatttttaag taaatctttt atcgatatta ttaagaatat
      241 atattacatc aagtttatta cgtgcaaacc actatcaact taaataccta aggtaacact
      301 tgaagtagta gattcttggt aacaataatt attgctatca ttatcttttt ttaattaagt
      361 atttactatt tatatatcaa tctacttttc acttttaatt taattctaac atttttttat
      421 atattttatg atatataatg tgatatattc taattaatga tattttcaag taaaaaaatg
      481 ttactctatt ataaggtgat agtatacttg aaaataaata aaacacttaa ctttatttaa
      541 ggagatttat gatgagtaac aaacaaggtt ctaacatcaa agatgtaaaa attaaaaata
      601 agttaataat attgaaatta ctttctacaa atacacctat gtccagagtt gatttagcta
      661 agtctacagg acttactaaa atgactttat caaatctagt tactgaactt attaatgaaa
      721 atatgattag ggaaatagag tcatcaactt taaatgcaca ttcatcaggt cgtaaaccta
      781 ttttattaga tatttctaat atatcgcctt gtatttgtgg aatcctaata agaagaaata
      841 tatgtaaggt aattatttca gatttaaaag gtaatattgt aaaacaactt tctgaaactt
      901 accccaaatg tctatcaaat gatgttttaa aagatataat aaaaagaatg tttactaaaa
      961 taatgaaaat caacaagaga gatataattg gaattggtat ttcttcaata ggtccagtag
     1021 atgatataaa tggtaccata ctaaatcccc cagattttgg aaatgtatca aacctaaata
     1081 tagtagattt tataaaagaa atgtctgatt tgccaatatt tttgataaat gatgctaatt
     1141 cgggtgcatt agcagaaaaa atgtatggtt taggtaaaaa tatatcaaat tatatatacc
     1201 tacacataat gaatggtatt ggagctggtc tagttctaga aaataaactt catactggca
     1261 acctaggaca aagtggagaa ataggacata catcaattaa ttttagtgga ccattgtgca
     1321 gttgtggtaa taatggatgt ttagattatt atacaagtgt cagtaatcta attaaaagaa
     1381 ttgaatcatt gagccatatt tatcctaact ccccattaat taactgtaaa gatttttctt
     1441 tagtcaagtt aatagatgag gcaaataata aagatagtct tgccatgttt ttg
//
LOCUS       DAEPKC010000210         1301 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.216, whole genome shotgun sequence.
ACCESSION   DAEPKC010000210 DAEPKC010000000
VERSION     DAEPKC010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1301)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1301)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1301
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.216"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..>1301
                     /locus_tag="KR294_003747"
     rRNA            <1..>1301
                     /locus_tag="KR294_003747"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          349 a          280 c          391 g          281 t
ORIGIN      
        1 agctgaggcc gaaaggcgta ggtgatggac aacaggttga tattcctgta ctaccgataa
       61 ccgtttgaga gaagggatga cacagtagga taagctaagc acactgttgg ttatgtgtgc
      121 ccaagcattg aggcagtcaa agtaggcaaa tccgctttga taatgctggg atgtgatggg
      181 gagcgaaatt tagtagcgaa gtagctgatt tcacactgtc aagaaaagtc tctatcgagg
      241 ttaaaggtac ccgtaccgca aaccgacaca ggtgggtgag gagagtatcc taaggccagc
      301 gagagaactg ttgttaagga actcggcaaa atgaccccgt aacttaggga taaggggtgc
      361 caccatcagg tggccgcaga gaataggccc aagcgactgt ttaccaaaaa cataggtttc
      421 tgctaagtcg caagacgatg tataggagct gacgcctgcc cggtgctgga aggttaaggg
      481 gatctgttag agcaatcgaa gcagtgaact taagccccag taaacggcgg ccgtaactat
      541 aacggtccta aggtagcgaa attccttgtc gggtaagttc cgacccgcac gaaaggcgta
      601 acgatttggg cactgtctca acaacagact cggtgaaatt gtaattccgg tgaagatgcc
      661 ggatacctgc gacaggacgg aaagacccca tggagcttta ctgtagcttg acattgggtc
      721 ttggtactac atgtacagga taggtgggag gctttgaaac caggacgcca gttttggcgg
      781 agccatcctt gggataccac ccttgtagta ctgggactct aaccataggc catgaatctg
      841 gtcttgggac actgtcaggt gggcagtttg actggggcgg tcgcctccca aaaggtaacg
      901 gaggcgctca aaggttctct cagtacggtc ggaaatcgta cgtagagtgt aaaggcaaaa
      961 gagagcttga ttgcaagaca tacaggtcga gcaaggatga aaatcggact tagtgatccg
     1021 gtggttctgc gtggaagggc catcgctcaa cggataaaag ctaccctggg gataacaggc
     1081 ttatctcccc caagagtcca catcgacggg gaggtttggc acctcgatgt cggctcatca
     1141 catcctgggg ctgtagtagg tcccaagggt tgggctgttc gcccattaaa gtggtacgcg
     1201 agctgggttc agaacgtcgt gagacagttc ggtccctatc cgtcgcaggc gtaggaaatt
     1261 tgagaagacc tgtccttagt acgagaggac cgggatggac g
//
LOCUS       DAEPKC010000211         1235 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.217, whole genome shotgun sequence.
ACCESSION   DAEPKC010000211 DAEPKC010000000
VERSION     DAEPKC010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1235)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1235)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1235
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.217"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            67..798
                     /locus_tag="KR294_003748"
     CDS             67..798
                     /locus_tag="KR294_003748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241757.1"
                     /translation="MLSKKNVSLIILVIILSLLTAIFIFNNKNTNNKLKEVTKNNEEI
                     VPKNLEGLSIEQLIEIRDKAIDKNLEGLREFGEDSVKKRKDSILNFEFGLVAFVNKNY
                     SNLTEKEKLIRQINIVNYENSINDIMDPSGSFFELANQNYQVNEFLLKNGKDYKEWSY
                     EGLDFLIDHLEELCKFVDFDVKDVIDIIDPTIKTDLSEEQKKSLNDKLKKISSSDTLS
                     EEVKKEIKNWENNLNNLNMNKNNSN"
     gene            complement(955..1161)
                     /locus_tag="KR294_003749"
     CDS             complement(955..1161)
                     /locus_tag="KR294_003749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241758.1"
                     /translation="MSKYSSLWEYFKKNNSQSFKLTFEEIKDIAGIEIDHSFLKYKKE
                     LNEYGYQVGKISLKEKTVIFDKIG"
BASE COUNT          513 a          131 c          150 g          441 t
ORIGIN      
        1 atgttatctt cataaacaaa tttatttttc acaagtacaa tacttattta aaaaaggagg
       61 tttaatatgt taagtaaaaa aaatgtaagt ttaattattt tagtaataat tttaagttta
      121 ttaactgcta tatttatttt caataataaa aatactaaca ataaattgaa agaagttact
      181 aagaataatg aagaaatagt acctaaaaac ttagaaggtt taagtataga acaattaata
      241 gagattagag ataaagccat tgataaaaat ttagaaggtc ttagggaatt tggagaagat
      301 tcagtaaaaa aacgtaaaga ttcaatttta aactttgaat ttggattagt agcttttgtt
      361 aacaagaatt atagcaactt aacagaaaaa gagaaattaa taagacaaat taatattgtt
      421 aactatgaaa actctataaa tgatataatg gatccttcag gttcattctt tgaattagca
      481 aatcagaatt accaagtgaa tgagtttcta ttaaaaaacg gaaaagatta taaagaatgg
      541 tcatatgaag gtctagattt tctaattgat catctagaag aactgtgcaa atttgttgat
      601 tttgatgtaa aagatgtaat agatattatt gatcctacaa taaaaacaga cctttcagag
      661 gaacaaaaga aatctttgaa tgataaatta aagaaaatat cttcaagtga tactttaagt
      721 gaagaagtta aaaaggagat aaaaaactgg gaaaacaatt taaataattt aaatatgaat
      781 aaaaataatt ctaattaatt ttctcataag aaaaatgctt atatcgtgat aatgtgaaat
      841 gtacataatt ataaacaaaa aaggggctgt gacactaaaa aatagtgcta cgcccttttt
      901 tatttgtaat aatcatcaat acaaattatt ttattatatg taattattta tgtcttaacc
      961 aattttatcg aaaataacag tcttctcttt taaagagatt tttcctactt gatatccata
     1021 ttcatttaat tcctttttat atttcaaaaa cgaatggtct atctctatcc cagcaatatc
     1081 ttttatttct tcaaaagtta atttaaacga ttgactattg tttttcttaa aatattccca
     1141 taaagaacta tatttactca tcttatatca ctccttttaa aatcatatct tatctattaa
     1201 tttatattct atcattatta atgtataaag tcatg
//
LOCUS       DAEPKC010000212         1210 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.218, whole genome shotgun sequence.
ACCESSION   DAEPKC010000212 DAEPKC010000000
VERSION     DAEPKC010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1210)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1210)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1210
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.218"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            142..876
                     /locus_tag="KR294_003750"
     CDS             142..876
                     /locus_tag="KR294_003750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBH0241759.1"
                     /translation="MNLAKGLDVLKISSNVFGEDKVMYIPVIYTEDDATLIDTGLPGQ
                     GDLIIDALNKSNTSFDKLKNIIITHHDIDHIGNINYLREKSKNNIKVYAYKSEISYIT
                     GEETPFKLYMLEQMVDKIDDKMLSMLNVMGLGFKSSYTKVDVSLDNHEKLNLGEEIEV
                     IHTGGHTRGHICLYLKESKVLIAGDLLQVENGELKPVDVMYSNKQELKDAIKNISNYD
                     IETIVFSHGGLYQRNIIGTLKNLIIE"
BASE COUNT          514 a          117 c          181 g          398 t
ORIGIN      
        1 gtcgagtaat ccttcaactt aaatgatata ctaggtatta ataattttta attaataaaa
       61 tataactaga ggaaaatcta cattttctca atttctttaa ttaaattgac ctctaattaa
      121 gtaattataa ggagaaaaat tatgaattta gcaaagggat tagatgtttt aaaaatttca
      181 tcaaatgtat tcggtgaaga taaagttatg tatattcctg taatctacac agaagatgat
      241 gcaacactta ttgacacagg tcttccgggt caaggtgatt taataattga tgctcttaat
      301 aaaagtaaca cgagctttga taagttaaaa aatataataa tcactcatca tgatatagac
      361 catataggaa acataaatta tctaagagaa aaatctaaga ataatatcaa agtatatgca
      421 tacaaaagtg aaatcagcta tataacagga gaagaaactc cttttaaact ttatatgttg
      481 gaacaaatgg tagataaaat tgatgataag atgcttagta tgctaaatgt tatgggactt
      541 ggatttaaat catcatatac taaagtagat gtgtcattag ataaccatga aaaattgaat
      601 ctaggtgagg aaatagaagt tatacataca ggaggtcaca ctagaggtca catatgtctt
      661 tatttaaaag agtctaaagt acttattgct ggagatttgt tacaggtaga aaatggagaa
      721 cttaagcctg ttgatgtgat gtacagcaac aaacaagagt taaaagatgc tattaaaaat
      781 ataagtaatt atgatataga aacgatagtt tttagtcatg gtggattata tcaaagaaac
      841 ataattggaa cattgaaaaa cctaattatt gagtagtact atatgattta caataatttc
      901 ttaaattact taaaattata tctaaagatg tagaatcaaa attaaatata agtaataaga
      961 attttgcttt aaaattatac ttaagtgtta agggtgatat gtagtattac aagtatttta
     1021 gaatataatt ttttatagta attttaaagt tctacaatac ttcagttgaa aaatatttaa
     1081 cagcatagta taataggaaa gaaaatattt taaataaact ttagtataca aagtgaagaa
     1141 aaatatttaa atcatgtatc ataatgcaaa gtaaagaaaa tcatttaaat tatatatcat
     1201 aaaaataata
//
LOCUS       DAEPKC010000213         1196 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.219, whole genome shotgun sequence.
ACCESSION   DAEPKC010000213 DAEPKC010000000
VERSION     DAEPKC010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1196)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1196)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1196
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.219"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            389..>1196
                     /locus_tag="KR294_003751"
     CDS             389..>1196
                     /locus_tag="KR294_003751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBH0241760.1"
                     /translation="MIAVKKAYKFRIYPNKKQQELINKTFGCCRFVYNKYLAKRIDVY
                     KNDKETFTYKQCSSDLTNLKKELNWLKEPDKFSLQNALKDLDNAYKKFFKEKAGFPKF
                     KSKKINRFSYKTNFTNGNIMYCGQHIKLPKLGMVKVRDKQVPKGRILNATISKEPSGR
                     YYVSLCCTDVDIEAFENTNNHIGLDLGIKEFCISSCGEFIENPKYLKKSLNKLAKLQR
                     ELSRKTIGSLNRNKARLKVARLQEHIANQRNDFLQKLSTKLIKENDIICIE"
BASE COUNT          513 a          131 c          184 g          368 t
ORIGIN      
        1 ctccaaatag gagaaacttc aacgactatt cctcttgagg gaagtacact acaagttatc
       61 ggtagtggaa gtgggtagac cttagcagat aatgccgaag gataagatat agtctgtgct
      121 tatgtgaaag tgtaagaagt tcataagaga actgcatagg tagtagcgaa cttatgtgaa
      181 cgacaacctc aaaaatgata aaagttaaga cttacggttc ttatatatgt tatttaaaat
      241 taaatataaa accttctaaa taattgtttt aaataattac atttgttaac attattatag
      301 gtgattaata aattgttcac cacagcatta tataatatat taaatattaa aatcattaaa
      361 aagtgtatca aaaaacaatt aaagtgaggt gatagcagtg aaaaaagctt ataagtttag
      421 aatatatcct aataaaaaac agcaagagtt aattaacaaa acttttggat gttgtaggtt
      481 tgtatataat aaatatcttg ctaaaagaat agatgtttat aaaaacgata aagaaacttt
      541 tacttataaa cagtgtagtt ctgatttaac caatttaaaa aaagaattaa attggcttaa
      601 agaacctgat aaattttcac tacaaaacgc cttaaaagat ttagataatg catataaaaa
      661 attctttaaa gaaaaggcag gatttcctaa atttaaatca aagaaaatta atagattttc
      721 atataaaact aactttacaa atggaaacat tatgtattgt ggtcaacata taaaactacc
      781 taaacttggt atggttaagg taagggataa acaagtacct aaagggagaa tacttaatgc
      841 tactatatct aaagaaccaa gtggtagata ttatgtatca ttatgctgta ctgatgtaga
      901 tattgaagca tttgaaaata ctaataatca tataggttta gatttaggaa ttaaagaatt
      961 ttgtatctca agttgtggag aatttataga aaatcctaag tatcttaaga agtcattaaa
     1021 caaacttgct aaattacaaa gagaattatc gagaaaaaca atcggtagtt taaatagaaa
     1081 taaagcaaga ttaaaagttg caagacttca agaacatata gctaatcaaa gaaatgattt
     1141 tctacaaaaa ctatctacta aattaataaa agagaatgat attatttgca tagaag
//
LOCUS       DAEPKC010000214         1184 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.220, whole genome shotgun sequence.
ACCESSION   DAEPKC010000214 DAEPKC010000000
VERSION     DAEPKC010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1184)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1184)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1184
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.220"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(313..804)
                     /locus_tag="KR294_003752"
     CDS             complement(313..804)
                     /locus_tag="KR294_003752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbM family protein"
                     /protein_id="HBH0241761.1"
                     /translation="MGMIGCYTKISEENVFKLQQAEENLQDFVFEDANENSTINIDKA
                     WHAIHFTLTGCPFGGDDDNIFSKLVLSGNILMEIDGEFPVMLITANDVKKLSKAMNSL
                     EEQAFRKRFNINEMLENNIYPVMNDESEDDFFEYVWANLIELKKFIQEASNDGLAVIF
                     FIM"
BASE COUNT          455 a          165 c          111 g          453 t
ORIGIN      
        1 ttgtgagtct atttttatat ataatgaaaa atgtgataag tatccaaaag aattactgga
       61 tataatagga tagggtattt agccttttaa gataaataaa aatatctgca actatatatt
      121 gcaaaaattt aaaactaatt tatatatgct aatataaata tttataaaga cataagacaa
      181 atttacctac agatttaaat ttaacttata tattttaaaa ggctaatata atatgtattt
      241 tcttctatac aatcaaaagg cttcatatct aagatatgtg atgacactaa tattcacaat
      301 ttttagtaat tatcacatta taaaaaatat tacagctagt ccatcattag atgcttcttg
      361 tataaacttt ttaagctcaa ttagatttgc ccatacatat tcaaaaaaat catcttcact
      421 ctcatcattc ataacaggat aaatattatt ttctaacatc tcattaatat taaatctttt
      481 tctaaatgct tgttcttcca aactgttcat tgcttttgat agttttttta catcatttgc
      541 tgtaatcaac atgacaggaa attctccatc aatttccata agtatgtttc cacttagtac
      601 taatttgcta aatatattat catcatctcc accaaaagga caacctgtca aagtaaagtg
      661 aatggcatgc catgctttat caatattgat agtactattt tcgttggcat cttcaaaaac
      721 aaaatcttgt aaattttctt ctgcttgctg taatttaaaa acattctctt cacttatttt
      781 agtataacat cctatcattc ccataattac attcctccta agtagcgttt ttttaattgt
      841 aacttataat taaacttagt tacaataaaa tatattgaga aaagtattat ttcatcttaa
      901 atttaaatac ctatattatc aactaaaatt ctgtgtttat agcgtaagta ttattttttc
      961 ctaaaaatta aatgaatcag aggttctata ggcaatattg actataaata agaactatta
     1021 ctttttaaaa aaaatttaag aaattatact gtagaatcat gctctactta ttagctttaa
     1081 ataaaaaata aatcatgttc tcaaattaaa taataaataa caataaattt aaattttaaa
     1141 ctataagagt ttctgaagtg ttaataagca taccaataat tata
//
LOCUS       DAEPKC010000215         1100 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.221, whole genome shotgun sequence.
ACCESSION   DAEPKC010000215 DAEPKC010000000
VERSION     DAEPKC010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1100)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1100)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1100
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.221"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(35..1009)
                     /locus_tag="KR294_003753"
     CDS             complement(35..1009)
                     /locus_tag="KR294_003753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009527294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBH0241762.1"
                     /translation="MFMINIVIPNYNGYKLLKNCLDSLKNQTYSNFSIIVVDNASDDS
                     SYNWLNNYENVTLKKLDKNYGFSKAVNEGIKLSNSKYVVLLNNDTVVPENWLETLLGE
                     IEKDESIFSVCSKMIRYNEKDKIDDAGDEYSILGWAYKIGDGKNISSFRKSKYVFSSC
                     AGAAIYRNSIFDEIGYFDEDFFAYMEDIDISYRAKIYGYKNRYCSEAKIFHIGSATSG
                     SKYNSFKVRLAARNNVYVPYKNMPFLQLIINMPFLIIGFLVKYLFFLKKGFGNDYKEG
                     FFEGIKNLKNLNKTEFRIKNLFNYLIIEALLILNMCKYIFSKVLDIYN"
BASE COUNT          394 a          184 c           84 g          438 t
ORIGIN      
        1 gcattacttc ttaatgaata atcaaatgat atatttaatt ataaatatct agtacttttg
       61 aaaatatata tttacacata ttcaatatca ataaagcttc tataattaaa taattaaata
      121 aattttttat tctaaattct gtcttattta gattctttaa attcttgata ccttcaaaaa
      181 aaccctcttt ataatcgttt ccaaatcctt ttttcaagaa aaacaagtac ttcactaaaa
      241 aaccaataat taaaaaaggc atgtttatta taagctgtaa aaaaggcata tttttatatg
      301 gtacatatac attgtttcta gcagccaatc ttactttaaa tgaattatat ttacttccag
      361 atgtagcact ccctatatga aatatttttg cttctgagca atatctattt ttatatccat
      421 aaatttttgc tctataagat atatcaatgt cttccatata tgcaaaaaaa tcttcatcaa
      481 aataacctat ctcatcaaaa attgaatttc tatatatagc agcacctgca caagaactaa
      541 atacatattt actttttcta aaacttgata tgttcttacc atctccaatt ttgtaagccc
      601 agcctagtat agaatattca tctccagcat catctatttt gtccttttca ttatatctaa
      661 tcattttgct acatacggaa aaaatactct cgtctttctc aatctctcct aatagtgtct
      721 ctaaccaatt ttcaggtact actgtatcat tgtttaacaa aacaacatat ttcgaattag
      781 ataattttat accttcattt actgccttac taaaaccata gttcttatct aattttttca
      841 gtgtaacatt ttcatagttg tttagccaat tatatgaact atcatctgat gcattatcta
      901 ctactattat actaaaatta gaatatgttt gattttttaa tgaatctaga caatttttta
      961 aaagtttata tccattataa tttggtatta ctatatttat catgaaaatt ctccatcttt
     1021 tcaactttaa attttatttt aatatgtaat taactctaag tacttaaaat tccaatacac
     1081 gcaattaccc aaaataaaac
//
LOCUS       DAEPKC010000216          968 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.222, whole genome shotgun sequence.
ACCESSION   DAEPKC010000216 DAEPKC010000000
VERSION     DAEPKC010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 968)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 968)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..968
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.222"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            58..813
                     /locus_tag="KR294_003754"
     CDS             58..813
                     /locus_tag="KR294_003754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1835 domain-containing protein"
                     /protein_id="HBH0241763.1"
                     /translation="MAHICFEDICYLLLKEAMKLKLIPHNKIVLFEDDLSIGNIFDVN
                     NYELRENIFKIRNVFENNPKLLFKPDLLEDRKLSKCRNIIIWCANNPKDLCGVYYVVS
                     KFQDKNIKIALVDEKKTEDALIRYSFTSEMSPEDFPFFLDKTLEIGFNEKLEFKNKWD
                     VLVKENSIFRALVGNEIKSVEETYFDKYILRNISDKWQPLIEVVANCMFEDEMRVKDW
                     FILWRLEKMASLKIVKIKGSKGDFYSDKEIRKV"
BASE COUNT          412 a           65 c          160 g          331 t
ORIGIN      
        1 attacagttt atatattata ataaaataaa ttgttaattt taaaagaggt gaattttatg
       61 gcacatatat gctttgagga tatttgttat ttgttattaa aagaagcaat gaagttaaag
      121 ttaataccac ataataaaat tgtattattt gaagatgatt tatcaatagg taatattttt
      181 gatgtaaata actacgaatt aagagaaaat atttttaaga ttagaaatgt ttttgaaaat
      241 aatccgaaac tattattcaa gccagatttg ttagaagata ggaaattatc aaaatgtaga
      301 aatataataa tatggtgtgc aaataaccca aaagatttgt gtggagtata ttatgtagtg
      361 agtaagtttc aagataaaaa tataaagatt gcattagtag atgaaaaaaa gacagaagat
      421 gctctaatta gatattcatt taccagtgaa atgtctccag aagattttcc attcttttta
      481 gataagacac tagaaattgg ctttaatgaa aaactagaat ttaaaaataa atgggatgtg
      541 ttagttaaag aaaattctat ttttagagca ttagtaggta acgaaattaa aagtgttgaa
      601 gaaacttatt ttgataaata tatattaaga aatatcagtg acaaatggca acctttaatt
      661 gaagtggttg caaactgtat gtttgaagat gaaatgcgtg taaaagattg gtttatactt
      721 tggagattag agaagatggc aagtttaaaa atagtaaaaa taaaaggaag taaaggggat
      781 ttttattctg ataaggagat aagaaaagtt taaaaattga atttataata aattgtatta
      841 aataatgggt ataactatga agaaaaatat cttaacagta ttaatattat aattagcaat
      901 aagtataata tttattctat aatttggaaa tataataact aataccttac gaataagtgt
      961 gctaaata
//
LOCUS       DAEPKC010000217          760 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.223, whole genome shotgun sequence.
ACCESSION   DAEPKC010000217 DAEPKC010000000
VERSION     DAEPKC010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 760)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 760)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..760
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.223"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            364..471
                     /locus_tag="KR294_003755"
     CDS             364..471
                     /locus_tag="KR294_003755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013483530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBH0241764.1"
                     /translation="MGRHLWNPSYFVATVSENTEEQIRKYINNQKKQVK"
     gene            473..>760
                     /locus_tag="KR294_003756"
     CDS             473..>760
                     /locus_tag="KR294_003756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH0241765.1"
                     /translation="MVVVEKAYKFRMYPNKKQQELINKTFGCCRFVYNKYLAKRIDVY
                     KNNKETFTYKQCSSDLTNLKKELKWLKEPDKFSLQNALKDLDNAYKKFFKEK"
BASE COUNT          316 a           81 c          137 g          226 t
ORIGIN      
        1 gagaaacttc aacgactatt cctcttgagg gaagtacact acaagctatt ggtagtggaa
       61 gtgggtagac cttaacggat aatgccgaag gataagatat agtctgtgct tacgtgaaag
      121 tgtaagaagt tcataagaga actgcatagg tagtagcgaa cttatgtgaa cgacaacctc
      181 aaaaatgata aaagttaaga cttacggttc ttatatatgt tatttaaaaa taaatataaa
      241 aaaacttcaa aatacttgtt ttaagtaatt gtatatttta atattatgat aggttatgaa
      301 aaatggaagt tactcatggt agaggatatg catatagtat gtcaaatata gacagccagt
      361 attatgggga gacatctttg gaatcctagt tatttcgttg ctactgtatc agaaaataca
      421 gaggagcaga taagaaaata tattaataat cagaaaaaac aagtaaagtg aggtggtagt
      481 ggtggaaaaa gcttataagt ttagaatgta tccaaataaa aaacaacaag agttaattaa
      541 caaaactttt ggatgttgta gatttgtata taataagtat cttgctaaaa gaatagatgt
      601 ttataaaaac aataaagaaa cttttactta taaacagtgt agttctgatt taaccaattt
      661 aaaaaaagaa ttaaaatggc ttaaggaacc tgacaaattt tcattacaaa acgccttaaa
      721 agatttagat aatgcatata aaaaattctt taaagaaaaa
//
LOCUS       DAEPKC010000218          677 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.224, whole genome shotgun sequence.
ACCESSION   DAEPKC010000218 DAEPKC010000000
VERSION     DAEPKC010000218.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 677)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 677)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..677
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.224"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            255..>677
                     /locus_tag="KR294_003757"
     CDS             255..>677
                     /locus_tag="KR294_003757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBH0241766.1"
                     /translation="MYNNIKNILKENHITFEEYDHEPILSFEKAKEIREKLQYTGVES
                     KSLFIKDRSGNYYIFVTTEGKKLDPKTIKNVLGGKVSICSKEELTQKTQCLPGCVSPF
                     GYEKNISLVIDQDIFNHDKIIFSPGIPEKTFIITASGFK"
BASE COUNT          303 a           67 c           79 g          228 t
ORIGIN      
        1 aaacattgaa aataaattaa actctaaaca catttaaata taaatttata tatcattttg
       61 acttggttaa acaatttcat acttatcgat ataaaaatag gttataatat aaatgttcat
      121 tatcttataa cctattttat ataatttatt cctaaaacat gtgaatgttt tttatgatag
      181 tttgaagaaa ttataaaatc actttataat tgaatattat atataaatta atttaaatat
      241 agaaaggaaa atatatgtac aacaatatca aaaatatttt aaaagaaaat catataacgt
      301 ttgaagaata tgaccatgaa cctattttat catttgaaaa agctaaagaa ataagagaaa
      361 aattacaata tactggagta gaaagtaaaa gtttatttat aaaagatagg tctggaaatt
      421 actatatatt tgtaaccaca gaaggaaaaa aattagatcc aaaaactata aaaaatgttt
      481 taggtggaaa agtatctata tgttcaaaag aagaattaac acaaaaaaca caatgtttgc
      541 ctggatgtgt atctcctttt ggatatgaga aaaatatctc tcttgtaata gatcaagata
      601 tatttaacca tgataaaata atcttttcac cagggatacc agaaaagaca tttattatta
      661 cagctagtgg atttaaa
//
LOCUS       DAEPKC010000219          636 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.225, whole genome shotgun sequence.
ACCESSION   DAEPKC010000219 DAEPKC010000000
VERSION     DAEPKC010000219.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 636)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 636)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..636
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.225"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(<1..634)
                     /locus_tag="KR294_003758"
     rRNA            complement(<1..634)
                     /locus_tag="KR294_003758"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          140 a          175 c          117 g          204 t
ORIGIN      
        1 ctacttaacg taactcgttg gcccgttcta caaaaagtac gcggtcacac aagaaatgtg
       61 cttccacagc ttgtaagtgc agggtttcag gttctatttc actcccctcc cggggttctt
      121 ttcacctttc cctcacggta ctatacgcta tcggtcacta ggtagtattt agccttggag
      181 ggtggtccct cctgcttccc acagggtttc acgtgtcccg tggtactctg gatcatatct
      241 aaagtcttct cgtttaacat acaggactat taccttctgt ggtgggtctt tccaaacctc
      301 ttcaattacg atacctcttc gttatgatat gtccgcaacc ccaataaaga aaactttatt
      361 ggtttgggct aatccgcgtt cgctcgccgc tacttacgga atcgaatttc tttctcttcc
      421 ttcaggtact tagatgtttc agttccctga gttcccctca ttaagctatg tattcactta
      481 atgatactta gacattactc taagtgagtt tcctcattcg gaaatcttcg gatcaaagtt
      541 tacgtgcaac tccccgaagc ttatcgcagc ttatcacgtc cttcatcggc tcctagtgcc
      601 aaggcatccg ccctgcaccc ttaataactt gaccag
//
LOCUS       DAEPKC010000220          611 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.226, whole genome shotgun sequence.
ACCESSION   DAEPKC010000220 DAEPKC010000000
VERSION     DAEPKC010000220.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 611)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 611)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..611
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.226"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..>611
                     /locus_tag="KR294_003759"
     rRNA            <1..>611
                     /locus_tag="KR294_003759"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          172 a          126 c          179 g          134 t
ORIGIN      
        1 tttaactgag cgttcagtta cttgacgtag acccgaaacc gggcgaccta cccatgagca
       61 ggatgaagcg aaagtaaaat ttcgtggagg tccgaaccca cgagcgttga aaagctcggg
      121 gatgacttgt gggtagcggt gaaattccaa tcgagcccgg agatagctgg ttctccccga
      181 aatagcttta gggctagcct caaggtgaga gatacggagg tagagcactg aatgtcctag
      241 ggggtattgc acctaccgaa gactatcaaa ctccgaatgc cgtcatctta tacttgggag
      301 tcagactgtg ggtgataaga ttcatagtcg aaagggcaac agcccagatc gtcagctaag
      361 gtccctaaat gtaagttaag tggtaaagga tgtgggattg cacagacaac caggatgttg
      421 gcttagaagc agccactcat tcaaagagtg cgtaatagct cactggtcga gtgatcctgc
      481 gccgaagatt tccggggcta aaacttacta ccgaagctac ggcatcagta atgatgggta
      541 ggggagcttc ccatacgggt tgaagcatga ccgtaaggac atgtggacag tatgggagtg
      601 agaatgttgg c
//
LOCUS       DAEPKC010000221          577 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.denovo.228, whole genome shotgun sequence.
ACCESSION   DAEPKC010000221 DAEPKC010000000
VERSION     DAEPKC010000221.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 577)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 577)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..577
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.denovo.228"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..>577
                     /locus_tag="KR294_003760"
     rRNA            <1..>577
                     /locus_tag="KR294_003760"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          154 a          121 c          190 g          112 t
ORIGIN      
        1 caggatggac ccgcgtctga ttagctagtt ggtaaggtaa cggcttacca aggcgacgat
       61 cagtagccga cctgagaggg tgatcggcca cattggaact gagacacggt ccaaactcct
      121 acgggaggca gcagtgggga atattgcaca atgggcgaaa gcctgatgca gcaacgccgc
      181 gtgagtgatg aaggccttcg ggtcgtaaaa ctctgtcctc aaggaagata atgacggtac
      241 ttgaggagga agccccggct aactacgtgc cagcagccgc ggtaatacgt agggggctag
      301 cgttatccgg atttactggg cgtaaagggt gcgtaggcgg tctttcaagt caggagtgaa
      361 aggctacggc tcaaccgtag taagctcttg aaactgggag acttgagtgc aggagaggag
      421 agtggaattc ctagtgtagc ggtgaaatgc gtagatatta ggaggaacac cagttgcgaa
      481 ggcggctctc tggactgtaa ctgacgctga ggcacgaaag cgtggggagc aaacaggatt
      541 agataccctg gtagtccacg ctgtaaacga tgagtac
//
LOCUS       DAEPKC010000222        10875 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.guided.116, whole genome shotgun sequence.
ACCESSION   DAEPKC010000222 DAEPKC010000000
VERSION     DAEPKC010000222.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10875)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10875)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10875
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.guided.116"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            39..656
                     /locus_tag="KR294_003761"
     CDS             39..656
                     /locus_tag="KR294_003761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HBH0241767.1"
                     /translation="MCKKMYLLVVGILIAGLLTACNGSPTKDSEQAQDNTKKEANVSN
                     NALKDEKNNENLMEQDFKVPYTDAINIFKDKYKDADIVDLSLERDLNKFVYTVEGVDD
                     NNEYKMKIDANTKDVLEDKTEKLDSEDLNGVARKEKLDFNDIMTPQQAMEIALKEQNG
                     MVKEWSLDKDLDVTFYKIRIDKDKNEYDIKVDSKKGTVLKVEKED"
     gene            764..3295
                     /locus_tag="KR294_003762"
     CDS             764..3295
                     /locus_tag="KR294_003762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBH0241768.1"
                     /translation="MSLKSLKIKENLYWVGSLDPDLRVFDIIMYTPYGTTYNSYVLKG
                     TEKTVLFETVKDKHFDNYIERLNDLNIDFEKIDYIVVSHTEPDHAGSVEKLLDLAKNA
                     KVVASETAIKYLKEIVNKDFEYVAVTDGDTLSIGDKTLEFFSVPMLHWPDTIYTYIKE
                     DKTLVTCDSFGSHYSNDKIVNTLDEDEEKDYLDALRYYYDCIMGPFKPSMVTAIEKIK
                     DLDIDTVCPGHGPVLTENPRKIIDLYYNWSVNEQIKLEKEVTICYVSAHGYTKIMAEA
                     IKAYIEKNSNYKVNLFDVIEHKQEDILAKIAVSQGVLFGTPTILGDALKPIWDILISL
                     NPVLHGGKVASVFGSYGWSGEGIENAMERISQLRMTAVKPFAVNFKPSNEEIDKLHSY
                     TGKFLDKLNSTFGSKKKTKKFKCVICNEVFEGDSAPSVCPVCGAKEDQFIEVEEDEVT
                     FRKDTDEYFVIVGNGAAGFYAADAIRKRNKTCKITMISNEDELTYYRPALSDGINEEL
                     GSDFYMEDKDWYDKNNIVVILGTNVDKLDEVNKTIIVNDGAIKFDKLVIATGSRNFIP
                     PIKGHDLENVFTLRNIKDLYSVKEALEKSKKVVVIGGGLLGLEAAWEFRLKGLEVVVV
                     EAMDSILSKQLDKEGSKILEQCVRDTGIDVRLGVAVDGIEGDGKAQKVVFKDGDSVDC
                     DMVVFSIGVRANTQMVQDTSVKIDRGIVVDKTLQTNVKDIYACGDVAQVGNISLAIWP
                     SSVEMGKIAGANASGDNLTFESEVYPVSLDAMNVKVFSIGNIQNFDKEISSKDEGQRI
                     YKKLFMKDGSLVGAILINDLSCTVKLIRLISEKGDFEDIMKADIL"
     gene            3729..4430
                     /locus_tag="KR294_003763"
     CDS             3729..4430
                     /locus_tag="KR294_003763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanG-Cd-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HBH0241769.1"
                     /translation="MNENILIVDDEKEIADLIEVYLKNEGFTVYKFYTGKEALECIES
                     KNLDMAILDIMLPDIDGFHICQKIREKYYYPIIMLTAKIEDIDKIMGLTIGADDYITK
                     PFNPLEVVARVKTQLRRYMRYNNSYEQQSIIVNEYDIKGLIINKETHKCSLFGKEVAL
                     TPIEFSILWYLCEHQGKVVPSEELFEAVWGEKYLDNNNTVMAHIGRLREKIHEPSKNP
                     KFIKTVWGVGYTIEK"
     gene            4480..5562
                     /locus_tag="KR294_003764"
     CDS             4480..5562
                     /locus_tag="KR294_003764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBH0241770.1"
                     /translation="MRTALMAFIAIIFIWILYSFILYGKFSIWIVSFFENAFRMEYKA
                     ALNLYQQIFRNSMELFMILAMVIVFFIIFRVYLNWFTKYFSEINQGIDSLIKEDVGEV
                     ALSPELLAIEKKINSIKHILEQRKFETQMAEQRKNELIVYLAHDLKTPLTSVIGYLTL
                     LRDESQISEELRKKYLSISLDKAERLEDLINEFFEITRFNLSNISLEYSTVSLTRMLE
                     QLTYEFKPTLMSKNLKYTLNVTPNMMIRCDVNKMQRVFDNLLRNAVYYSFEDTTIEIT
                     AVQEDDYIKLKFINHSNTIPEEKLERIFEQFYRLDTSRNSNSGRAGLGLAIAKEIVEL
                     HNGTITAHSENNIITFKVIIPIVGNL"
     gene            5823..6923
                     /gene="vanG"
                     /locus_tag="KR294_003765"
     CDS             5823..6923
                     /gene="vanG"
                     /locus_tag="KR294_003765"
                     /EC_number="6.3.2.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-serine ligase VanG"
                     /protein_id="HBH0241771.1"
                     /translation="MNNKKIAVIFGGNSTEYDVSLQSAFAVLENLNTEKYDIIPIGIT
                     REGNWYHYIGDYNNIQNNTWFERDTDIIPVIVSQNRVKNGIIEFLIPDAVSQNHIPNS
                     AIESCENDIKYTKLDFVFPVLHGKNGEDGTVQGLFELAGIQVIGCGTLSSALCMDKDK
                     SHKLVHSEGIKVPKSILLKYSDKFNVAELSKDLTYPLFIKPVRAGSSFGISKIYKKEE
                     LQVAVDLAFEHDNEVIIEENIDGFEVGCAVLGNNDLLVGRVDEIELSKGFFDYTEKYT
                     LKSSKIHMPARIDLDCEKRIQETAKIIYRTLGCSGFARVDMFLTPSGEIIFNEVNTIP
                     GFTSHSRYPNMMKGIGLSFEEILDKIIEVYIK"
     gene            6920..7726
                     /locus_tag="KR294_003766"
     CDS             6920..7726
                     /locus_tag="KR294_003766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HBH0241772.1"
                     /translation="MMNNILLDKNKEDKMTNTILLTKDKVYDGNLILVNAFLPVKTSE
                     DIDLIPVDTRFPSILMKREATNILQNILKSICGINEIVPVSGYRTAEEQQDIYSSSLR
                     DNGKDFTKKFVALPNHSEHQTGLAIDLGLKKEVIDFICPEFPYNGICNEFRKAALHYG
                     FIERYQCKKEEITGISQEPWHFRYVGYPHSEIINKMNLALEEYIEYIKRFSYTNCLKI
                     EDKEKIIEIFYVPIHTKEEVRISIPEQCVYQISGNNKDGFIVTFWRNRKD"
     gene            7744..9882
                     /gene="vanT"
                     /locus_tag="KR294_003767"
     CDS             7744..9882
                     /gene="vanT"
                     /locus_tag="KR294_003767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine racemase VanT catalytic subunit"
                     /protein_id="HBH0241773.1"
                     /translation="MIRNKSYAGLDYFRIIAALLIIAIHTSPLLSYSKMADFVLTSII
                     ARIAVPFFFMLSGFFLISTYNYNCNKLKSFLKNVLFIYGIAIVIYIPLNIYTGYFSMN
                     NLVPNIIKDIVFDGTLYHLWYLPASIIGASIAYFLVKKLGLKYSLVITIVIYVIGMFG
                     DSYYGFLEKIPLLKNLYGYIFEVSDYTRNGIFFAPVFFILGGIISNKSNYMSTKNSLI
                     GFLISFLLMLCEGMFLHKLGVQRHDSMYIMLLPCMYFLFTALTFLKGSRARLLRTSSL
                     IIYIIHPMMIVVIRMFSKIFGIQTVLVDNSLIHYIVVSIASFIASIIIILILKPLKKD
                     LKGEHKVNTNRAWIEIDLNNLEHNVKMIQKAMPEDCELMAVVKANAYGHSAFEVATCA
                     NQIGVKAFAVATIDEGIDLRRYGILGEILILGYTNPIRAKELHKYNLTQSVIDLNHAI
                     SLNKQKYNIKSHIKIDTGMHRLGFDVNDVRSILKAFKLKYLDICGIFTHLCVSDSLKD
                     EDVDFTNKQIECFYKLIDFLLKKGIKIPKVHIQSSYGFFNYPNLKCNYVRIGIALYGI
                     LSFPNDTTKLQLDLRPVLSLKSQVILIRKIQKDDSFGYGRVFIASRDSVIAILSIGYA
                     DGIPRNLSCGKSYVIINGCRAAIVGRICMDQLAVDITDIPNVEVGNTAIIIGRDNLSE
                     LSVSEVANNSCSISNELLSRVGRRLNVIKK"
     gene            10196..10816
                     /locus_tag="KR294_003768"
     CDS             10196..10816
                     /locus_tag="KR294_003768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBH0241774.1"
                     /translation="MQYIQELLDLTQNYWVLATIIGLLSAFIESFIPALPLVAIVTAN
                     AAIQGLFIGCLLSWIGSGLGTTSLFLLISRFNDSKLFNKLRNSKTEKAISWMDKQGFK
                     LLFIAYACPFMPGCLVTIASAFGKKDLKDFVPAMLAGKFVMFIVISYVASDIEGFITS
                     PLKIASFILLVFLSWKIGNRVNKNLENHNYDFHHKKHHNDKDDKMI"
BASE COUNT         4120 a         1144 c         1953 g         3658 t
ORIGIN      
        1 ataatataga ataaattaat tatttaagga gggtttttat gtgcaaaaaa atgtatttat
       61 tagtggtagg tatacttata gcaggtttat taactgcatg taatgggagt ccaactaagg
      121 attcagaaca agcacaagat aatacaaaaa aggaggcaaa tgtatcaaat aacgctttaa
      181 aagatgaaaa aaataatgaa aatttaatgg aacaagattt taaagtgcca tacacagatg
      241 caataaacat atttaaagac aaatacaaag atgctgatat agtagattta agtcttgaga
      301 gagatttaaa taaatttgtt tatactgtgg aaggtgtaga tgataataat gaatataaga
      361 tgaaaattga tgctaataca aaagatgtat tagaagataa aacagaaaag ttggattcag
      421 aagatttaaa tggagtcgct agaaaagaaa aattagattt taatgacata atgacacctc
      481 aacaagctat ggaaattgca ttaaaagaac aaaatggaat ggttaaagag tggagtttag
      541 ataaagattt agatgttact ttttataaaa taagaataga taaagataaa aatgaatatg
      601 acataaaagt agattctaaa aagggaactg tattgaaggt agaaaaagaa gattagaaga
      661 tttaaactat ctttaaaata atttcttttt tgaataaaat ttgtttaaaa tataacaagt
      721 agggtataaa gagactaaat aactatttta ggaggagtac ggtatgtcat tgaaatcgct
      781 aaaaataaaa gaaaatttat attgggtagg ttcgcttgac cctgatttaa gagtatttga
      841 cataattatg tatacacctt atggaactac ttataattca tatgtattaa aaggaacaga
      901 aaaaacagtt ttatttgaga cagttaaaga taagcatttt gacaattata ttgaaagatt
      961 aaatgattta aatatagatt ttgaaaaaat agactatatt gttgtaagtc atactgaacc
     1021 agaccatgca ggaagcgttg aaaagctttt ggatttagct aaaaatgcaa aagtagtagc
     1081 ttcagaaaca gcaattaaat atcttaagga aatcgtaaac aaagactttg aatatgttgc
     1141 agttacagat ggagatacat tatcaattgg ggacaaaact ttagaatttt tctctgtacc
     1201 tatgcttcat tggccagata ccatatacac atatataaaa gaggataaaa ctcttgtaac
     1261 atgtgattca tttggtagtc actatagtaa tgataagata gtaaatacac ttgatgaaga
     1321 tgaagaaaag gattacttgg atgctttgag atactattat gattgtataa tgggaccatt
     1381 taaaccatct atggtaactg ccatagaaaa gataaaagat ttagatatag atactgtatg
     1441 tccaggtcat ggtccagtat taactgaaaa tcctagaaaa attatagacc tttattacaa
     1501 ctggagtgta aatgaacaaa taaagttaga aaaagaagtt acaatttgtt atgtttctgc
     1561 acatggatat acaaagatta tggcagaagc tataaaagca tatattgaaa aaaatagcaa
     1621 ctataaagta aatttatttg atgtaataga gcataagcaa gaagatattt tggcaaaaat
     1681 agcagtatca caaggtgtat tatttggaac accaacaata ttaggagatg cgttaaagcc
     1741 tatatgggat atattaatat cgttaaaccc agttcttcat ggtggaaaag ttgcttcagt
     1801 atttggttca tatggatgga gtggagaagg tatagaaaat gctatggaga gaataagtca
     1861 gcttagaatg acagcagtaa aaccttttgc tgttaacttt aaaccatcaa atgaagagat
     1921 tgataaatta cattcttata caggtaaatt cctagataag ttaaattcta cttttggaag
     1981 taaaaagaaa actaagaaat ttaaatgtgt aatttgtaat gaagtttttg aaggtgatag
     2041 tgctcctagt gtatgccctg tatgtggagc taaggaagac caatttatag aagttgaaga
     2101 agatgaagtt acttttagaa aagatactga tgaatatttc gtaatagtag gaaatggagc
     2161 agctggtttt tatgcagcag atgctataag aaaaagaaat aaaacttgta agataactat
     2221 gatttctaat gaagatgagt tgacttacta tagacctgca ctttctgatg gtataaatga
     2281 agaacttggt tcagatttct acatggaaga taaagattgg tatgataaaa ataatatagt
     2341 agtaatatta ggaacgaatg tagataaatt agatgaagtg aataaaacta ttatagtgaa
     2401 tgatggagct attaaatttg ataagcttgt aatagctaca ggaagtagaa actttatacc
     2461 accaattaag ggtcatgatt tagaaaatgt gtttactctt agaaatataa aagatttata
     2521 tagtgtaaaa gaagcactag aaaaatctaa gaaagttgta gtgattggtg gcggtttatt
     2581 gggacttgaa gctgcatggg aatttagact aaaaggatta gaagtagtag tagttgaagc
     2641 catggatagc atactatcaa aacaacttga taaagaaggc agtaaaatat tagaacaatg
     2701 tgtaagagat acaggaatag atgtaagatt gggtgtagca gttgatggta ttgaaggtga
     2761 tggaaaagct caaaaagttg tatttaaaga tggagatagt gttgactgtg atatggtagt
     2821 attttcaatt ggtgtaagag caaacactca aatggttcag gatacatctg taaaaattga
     2881 cagaggtatt gttgtagata agacattaca gacaaatgtt aaagatatat atgcttgtgg
     2941 agatgttgca caagtgggaa atattagttt agcaatatgg ccatcttcag tagaaatggg
     3001 aaaaatagca ggggcaaatg caagtggaga taatttgaca tttgaaagtg aagtatatcc
     3061 agtttcatta gatgcaatga atgtaaaagt atttagtatt ggtaatatac aaaattttga
     3121 taaagaaatt tcatcaaaag atgaaggtca aagaatatat aaaaaattat ttatgaaaga
     3181 tggttcatta gttggagcta tacttataaa tgatttaagc tgtactgtta aattgataag
     3241 attaatatct gaaaaaggtg attttgagga tattatgaag gctgatatac tataatttaa
     3301 atacattaaa ataaaaagga gttgtcttaa aattgatttt tttctaatca aattttaaat
     3361 tcaactcctt ttttgaattt ttatataaaa taacatggaa attttagtaa tgtctgtggt
     3421 tacatacata ggtttaattg ttttttatat ggattgtctc tggtataata aattgaattg
     3481 tgtttgactg atagatattt ttattgaaag ttaatacctg ttatgcgata ataaggacgt
     3541 gttaggggag tttttataat aacaattaat ctcagttttt gtgttccaat agtagcatca
     3601 acacattctg atgtagtagt tcttttctta taaaaattag ttacaaatat gcttgtaatt
     3661 atttgatatg taaatttacc aatattataa atgatgacct cgataataag gagagtgaaa
     3721 aataatctat gaacgaaaat attttgattg tggatgatga aaaagaaata gcagatttaa
     3781 ttgaagtata tttaaaaaat gaaggtttta cagtatacaa gttttataca ggtaaggaag
     3841 ctctagaatg tattgaatct aaaaatttgg atatggctat tttagatatt atgcttcctg
     3901 atattgatgg atttcatatt tgccagaaaa ttcgagaaaa atactattat cctatcatta
     3961 tgttaacagc taaaattgaa gatatagaca agataatggg tttaaccata ggtgctgatg
     4021 attatataac aaagccattt aaccctttgg aagttgttgc aagagtaaag acacaattaa
     4081 gaagatatat gcgatataat aattcttatg aacaacagtc gataattgtt aatgagtatg
     4141 atattaaagg attgattatc aataaagaaa cacataaatg tagtttattt gggaaagaag
     4201 tagcattaac accgattgaa ttttctattc tttggtattt atgtgaacat caaggaaaag
     4261 tggttccttc tgaagaattg tttgaagctg tatggggaga aaaatatctt gataataata
     4321 acacagttat ggctcatata gggcgattac gtgaaaaaat tcatgaacct tctaaaaacc
     4381 cgaaatttat aaaaactgta tggggagtag gttatacaat tgaaaagtaa aaatattaaa
     4441 gtcaatcctg actttactca agtgagaaat aaaattttta tgagaacagc tttaatggca
     4501 tttatagcca ttattttcat atggatttta tattctttta tattgtatgg taagttttct
     4561 atctggatag tatcattctt tgaaaatgct tttcgtatgg aatataaagc tgcattgaat
     4621 ttatatcagc agattttccg taatagtatg gagctcttca tgatactagc tatggtgatt
     4681 gtgtttttta taatattccg tgtttattta aattggttta caaaatattt tagtgaaata
     4741 aatcaaggta ttgactctct tatcaaagaa gatgttggag aagtggcttt atctccagag
     4801 ttattggcaa tagaaaagaa aataaactca attaaacata tacttgaaca acgtaaattt
     4861 gagacacaaa tggcagaaca acgtaagaat gaacttattg tttatcttgc acatgattta
     4921 aaaacaccac ttacatcagt tatagggtat ctgacactac ttcgagatga aagtcagatt
     4981 tctgaagaac tgcgaaaaaa atatttatct atttcgttgg ataaggcaga gcgtcttgaa
     5041 gatttaatta atgaattctt tgaaattaca aggtttaatt tatcaaatat atcacttgaa
     5101 tacagtacag taagcttaac tcgtatgctt gaacaactaa catatgagtt taaacctact
     5161 ttgatgagta agaatttaaa atatacactg aatgttacac caaatatgat gataaggtgt
     5221 gatgttaata aaatgcaacg tgtatttgat aacttattac gaaatgctgt ttattatagt
     5281 tttgaagata ctactattga aataacagct gtacaggagg atgattatat aaagcttaaa
     5341 tttataaatc atagcaatac gattccagag gaaaaacttg agcgtatttt tgaacaattt
     5401 tacaggttgg atacatctcg taattcaaac agtggtagag ctgggttggg acttgctata
     5461 gctaaagaaa tagtggagct tcataacggg acaataacag ctcatagcga gaacaatata
     5521 attaccttta aggttattat tccgattgta ggaaatttgt aagaatttaa gtataaaaaa
     5581 ataggaaatt ctttaggata aataaataaa gagcactctt gttattgata taattactgt
     5641 atcaaaacaa gagtgctttt attttgatac agtaattata tcaatagaaa aatgtgaaaa
     5701 tatattatgt ggaacagatg caattgtaag tgaaggttga ttggatttga aatagaaaaa
     5761 gtattttaac atgtttctgt agattgtata aaaataaata aatcaacaaa ggagaatcaa
     5821 agatgaataa taaaaaaatt gcagttatat ttggtggaaa ctcaacagaa tatgatgtat
     5881 cattacaatc agcttttgca gtacttgaga atttgaatac ggaaaaatat gatattatac
     5941 caattggaat tacaagggag ggtaattggt atcattatat tggagattat aataatatcc
     6001 agaataacac ttggtttgaa agggatactg atataattcc agttattgtt tcgcagaacc
     6061 gtgtcaaaaa tggtattatt gaatttttaa ttcctgatgc tgtttctcag aatcatattc
     6121 caaatagtgc tattgaatca tgtgaaaatg atattaaata cactaaactt gattttgtgt
     6181 ttcctgtact gcatggaaaa aatggagaag atggaacagt gcaggggtta tttgaattgg
     6241 caggtataca ggttattgga tgtggtactc tttcttcagc attatgtatg gacaaagaca
     6301 aatcacataa acttgttcat tcagaaggta ttaaagtacc aaaatcaata ttactaaaat
     6361 actcagataa atttaatgtg gctgaactgt caaaagactt aacttatcca ttatttataa
     6421 aacctgtgcg tgcaggttca tcatttggta ttagtaaaat ttataaaaaa gaagagttac
     6481 aagtagcagt agacttggct tttgaacatg ataatgaagt aataattgag gaaaatattg
     6541 atggttttga ggtagggtgt gcagttttag gaaacaatga cttacttgtt ggaagagtag
     6601 atgaaataga attgtcaaaa ggattttttg attatacaga aaaatataca ttgaaaagtt
     6661 caaaaattca tatgccagct agaattgatt tggattgtga gaaaagaata caagagacag
     6721 caaaaattat ttatagaact cttggatgtt ctggatttgc tagagtagat atgtttttaa
     6781 ctccatctgg tgaaattatt tttaatgaag tcaatacaat tcctggcttt acttctcata
     6841 gtcgttatcc aaatatgatg aaaggtattg gactgtcttt tgaagaaata ttggacaaga
     6901 taattgaggt gtacataaaa tgatgaataa tattttatta gataaaaata aagaagataa
     6961 aatgacaaat actatcttat tgactaaaga taaagtttat gatgggaatc taattctagt
     7021 aaatgctttt ttaccagtta aaacatctga agatatagat ttaattcctg tagatacaag
     7081 gtttccaagt attcttatga aacgtgaagc tacaaacatt ttacaaaata ttttaaaaag
     7141 tatatgtgga ataaatgaaa tagtacctgt aagtggatat cgtactgcag aggaacaaca
     7201 agatatatat tcaagttctc tgcgtgacaa tggaaaagac tttactaaaa agtttgtagc
     7261 acttccaaat cacagtgaac atcagacagg gcttgctatt gatttagggt taaagaaaga
     7321 agttatagat tttatctgcc ctgaatttcc ttataatggt atttgtaatg agtttcgtaa
     7381 ggcagcacta cattatggtt ttatagagcg ttatcagtgt aaaaaagaag aaataacagg
     7441 aatatctcaa gaaccatggc attttcgtta tgtgggatat ccgcattctg agattatcaa
     7501 taaaatgaat ctcgctcttg aagaatatat agaatatatt aagagatttt cgtatacaaa
     7561 ttgtttaaaa atagaagata aagaaaaaat tatagaaatc ttttatgtgc ctattcatac
     7621 taaagaagaa gtgagaatct ctatacctga acaatgtgta tatcaaatat cgggtaacaa
     7681 taaggatggt tttattgtga cattttggag aaatagaaag gactaagaaa tggaggaaca
     7741 agaatgatta ggaataaatc ttatgcaggg cttgattatt ttaggattat agctgcatta
     7801 cttataattg caattcatac atctccatta ttatcatata gtaaaatggc tgactttgtg
     7861 ttaactagta taattgctcg tattgctgtg ccattctttt ttatgctatc aggctttttt
     7921 ctaatttcaa catataatta taattgtaat aaactgaaat cttttctaaa aaatgtatta
     7981 tttatttacg ggatagctat tgtaatttat attcccttaa atatttacac tggatatttt
     8041 tccatgaata atttagtgcc caatattatt aaggacattg tatttgatgg gactttatat
     8101 catttatggt atcttcctgc atcaattatt ggtgcaagta ttgcatactt tcttgtaaaa
     8161 aaactaggtt taaagtactc actagtaatc actattgtta tttatgtaat tggtatgttt
     8221 ggtgatagtt attatggttt tttagaaaaa ataccactat taaagaattt atatgggtat
     8281 atttttgaag tatcagatta tacacgaaat ggtatatttt ttgcacctgt atttttcata
     8341 cttggtggaa taatatctaa taaatctaat tatatgtcaa ctaaaaatag cttgattgga
     8401 tttcttatat cattcttact tatgttatgt gagggaatgt ttttacataa actaggggta
     8461 cagcgtcatg atagcatgta tattatgtta ttgccatgta tgtatttctt atttacagcc
     8521 ttaacatttt tgaaaggttc tcgagctagg ttattgcgaa catcatcatt aattatttat
     8581 attatacatc ctatgatgat tgttgttatt cgtatgtttt ctaaaatatt cggaatacaa
     8641 actgtcttgg ttgacaatag ccttattcat tatatagtgg taagtatagc atcttttata
     8701 gcttctataa ttattatatt gattcttaaa cctctaaaaa aagacttgaa aggagaacat
     8761 aaggtaaata ccaatagagc ttggattgaa attgatttaa ataatttgga acataatgta
     8821 aagatgatac aaaaagctat gccagaagat tgtgaattga tggcagttgt aaaagctaat
     8881 gcctatggtc atagtgcttt tgaagtagcg acttgtgcaa accaaatagg tgtaaaagca
     8941 tttgcagtag caacaataga tgaggggatt gatttacgtc gatatggaat actaggagaa
     9001 atattgattc ttggatatac taacccaata agggcaaagg aacttcataa atacaatctt
     9061 acacagagtg ttattgacct taatcatgct atctctttaa acaaacagaa atacaacata
     9121 aaatcacaca ttaaaattga tacaggtatg cacagactgg gttttgatgt taatgatgtg
     9181 aggtcaattt taaaggcatt taaattaaaa tacttagata tatgtggcat atttacacac
     9241 ttgtgtgttt cagatagtct gaaagatgaa gatgtagact ttacaaataa acaaattgaa
     9301 tgtttttata agttaattga ttttctgtta aaaaaaggta taaaaattcc taaagtacat
     9361 attcaaagta gttatggttt ttttaattat cccaatctta agtgtaatta tgtaagaatt
     9421 ggaattgcat tatacgggat attaagtttt ccaaatgata cgactaaatt gcaacttgat
     9481 ttacgacctg ttttatcctt aaaatcacaa gtaattctta ttagaaaaat acaaaaagat
     9541 gatagttttg gatatggaag agtctttatt gcaagcagag atagcgtaat tgctatatta
     9601 tctattggct atgccgatgg tatacctaga aatttatcct gtggaaaaag ttacgtaata
     9661 ataaatggtt gtagagcagc aatagtgggt cgaatttgca tggaccaact tgctgttgat
     9721 attacagata tacctaatgt agaagttggt aatacggcaa taataatagg aagagataat
     9781 ttatctgaat tatctgtttc tgaagttgca aataactcat gtagtatatc gaatgaatta
     9841 ttgagcagag taggaagaag gttaaatgtt ataaagaagt aactcaatta aatagtaata
     9901 tttgttgtac tgtgtaattt attttactct gactagacat ttttagtaat attatgtcta
     9961 atatatattt tttataactt acatgacaat ttaagttata aaaaggtgat gtttcagatt
    10021 tttattttga aacatcacct tttttgttat aatatataat aaaataatta taccttaact
    10081 gtaaacttat atagattatt tactttttaa tattagattc attttttgag attggtatat
    10141 aataaacata tagagtatat aataatagtt aaagttaaaa aaggggaaaa gcaatatgca
    10201 gtatatacaa gaactacttg atttgactca aaattattgg gtgttagcca caataatcgg
    10261 cttattaagt gcatttatag aaagctttat accagcctta ccacttgttg ctatagttac
    10321 agcaaatgct gcaatacaag gattatttat tggatgtttg ttatcatgga ttggctcagg
    10381 acttgggaca acttcattat tcttattaat aagcagattt aatgatagta agctttttaa
    10441 taagttgaga aatagtaaaa ctgaaaaagc aataagttgg atggataaac agggatttaa
    10501 gttattattt atagcgtatg cctgtccatt tatgcccggt tgtttagtta ctatcgcatc
    10561 agcttttggt aaaaaagatt taaaagattt tgtgccagca atgttggcag gaaaatttgt
    10621 aatgtttata gttataagtt acgtggcaag tgatatagaa ggttttataa caagtccttt
    10681 aaagatagca tcatttatat tattggtgtt tttgtcatgg aagattggaa atagagtaaa
    10741 taaaaatctt gaaaatcata attatgattt ccatcataaa aaacatcaca atgataaaga
    10801 tgataaaatg atttagcttg tacgaaataa aacgtatctt aaaatgattt agtactaaat
    10861 tattttaaga tacgt
//
LOCUS       DAEPKC010000223         7600 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.guided.138, whole genome shotgun sequence.
ACCESSION   DAEPKC010000223 DAEPKC010000000
VERSION     DAEPKC010000223.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7600)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7600)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7600
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.guided.138"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            278..1231
                     /gene="blaCDD"
                     /locus_tag="KR294_003769"
     CDS             278..1231
                     /gene="blaCDD"
                     /locus_tag="KR294_003769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDD family class D beta-lactamase"
                     /protein_id="HBH0241775.1"
                     /translation="MKRKKNFIWIAILLVGVVMVMYYVGKKHNDINQKTDKNYIKSEL
                     NKSELNKSKIENNDKNKKEKINMVDYSDCFEGISGGAIFYNTKNKEYNIYNKELIETR
                     RSPCSTFKIVSTLIGLEKGVINSKESVMGYDGTEYPNKNWNKNLSLEEAFKESCVWYY
                     KKLIDKVDAKSVQNILDDLKYGNCDISEWEGDLKNGKGHLNGFWLESSLQISPKEQVQ
                     TMAKIFEGDTNFKKEHINILRDIMKIDINDKNINVYGKTGTGFDEKNKRVDAWFVGML
                     EREGDTYYFAIKSDDSNKEITGPKVKEIAINIIKKYYSVRE"
     gene            1575..2258
                     /locus_tag="KR294_003770"
     CDS             1575..2258
                     /locus_tag="KR294_003770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0241776.1"
                     /translation="MEILKCENLTKIYGSNQTRVTALNNVNLSVQKGDFVSIVGASGS
                     GKSTLLHLLGGVDRPTSGKIYVEDTEISSLKEEALAVFRRRKVGLIYQFYNLIPTLDV
                     RKNILLPMLLDKRKVDEDRFSEIVSILGLSDRLNHLPSQLSGGQQQRVSIARSLIYRP
                     AILLADEPTGNLDRKNSEEIVDLLNLSNKRFNQTILLITHDEKIALEANRIVTMEDGV
                     IVSEKVVKK"
     gene            2255..4915
                     /locus_tag="KR294_003771"
     CDS             2255..4915
                     /locus_tag="KR294_003771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0241777.1"
                     /translation="MNILQEYTLDFVRRNKRSSIAIMLAILLTTTMMSSLCGLLYTMW
                     TDFIRLSIEKEGNWHGELFDYTYGSDLPLIENFSSVDDVMVKGQWYVGKINDEKRDYI
                     IYRNATSEYWNSMPEKDTIIEGRRPNNANEIALSKQYFENNPSVKIGDKITLPIGYRI
                     LNGKPLEPIAPKSKGESFKKISEATLTIVGKVDVSTSSVIPAYTALGYLDKTSIKPND
                     SITVYLRFKNIRDTYKELPKLAKSLGWKTNEYGKYNLKYNSNYLLKMLVFSPEQKASM
                     SSISKFSTPIMYLTIAIFTVAVFVMVIYNAFSLSANARLTQLGILSSVGASPKQIKRS
                     VVFEGFLLTIIPLPIGLFLGWLLCNRLIVYVNSVNYHTDVPEVVFTYGIPAFLPAVLL
                     TIVTVWISALIPARKVSKISPIEAIRQGDSVKIKKSHKYSLGKIFGIEGELASNALRA
                     RKKSYRTATISLTLSFLLLTCFLHIIANQEGAKAVYGSDNYKDQRDIAVYLENSEPIE
                     SAFIEKLDNTEGVKSSLYYQKMSASTWLTEKDASKELAKNGGFKSIVSSKKYSPIERD
                     GKFRIISNIIGLDDKSFTEYCRQISVDPKLFYNTKNPTSIVYNKEEDINRSTRRNKVY
                     IDYLNLSIGDNIKLNEKVYDEDKGDYTYNMKVGAITSTLPKIVDTSSKYTLMQIVPMS
                     MVQEISKNYDEVSRLRSNRLIGVFKVNNREDIPRVREKLESIYNKDYGSGDYSIEDVL
                     ESEKQKASGIKTMNLIVGFITGLLAMIGLSNVLATVSGNIRSRRQEFAMLRSVGLSPE
                     GIKKMLILEGLFLGITPLLLSIPVQIGIVYAFLRINEIYFIEYLPFAPISTIIGFTIL
                     ILFIVIASYMTGYKQLKNENIVESIKNETI"
     gene            complement(5096..6277)
                     /locus_tag="KR294_003772"
     CDS             complement(5096..6277)
                     /locus_tag="KR294_003772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH0241778.1"
                     /translation="MKTPRNINSTVVFIIFCLIVTFLLSVILTTITSFNEYNVLSKAL
                     GASYEYNPKSTESILKSLKNSSDKDFKTGNEILSKHGYSKSTFWSKNFFYFLVISFGI
                     ISTMATVIYIIKHRTNKQKLSRINNLTQYLEEVNLGKESVLLRCEDEFSHLEDEIYKT
                     VGELRCSKEFALKERQTLSDNLADIAHQLKTPITSMSLMAQLLSENCPDEEIDYINRL
                     TNQISRLERLVSSLLTLSKLDASTLIFESKLIDVHSLLTYAIEPIEGSLREKHQTFTI
                     EASPSVEFEIDINWTLEALLNILKNCSEHIEDGGYIVAYYSQNPLYVEIIIEDNGKGF
                     AQEELPYIFNRFYRGKNASKDSIGIGLALSKSIIERQNGTLHAENCHNGGARFIIKFY
                     T"
     gene            complement(6277..6939)
                     /locus_tag="KR294_003773"
     CDS             complement(6277..6939)
                     /locus_tag="KR294_003773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0241779.1"
                     /translation="MAKILLLEDDDTITFGIKTSLEKKNHTVCCYNTIAEAKKNFDKT
                     IDLILLDLNLPDGIGYEFCQYVKSIEDTPVIFLTVRDDEKDIIRGLDMGADDYVVKPF
                     LLSVLQSRINAVLRRTHSNTNNTITCENISLNKVEVKAYLDNVEVPLTAGEYKLLLSL
                     MENKNRAMTRTKLLEMLWDVDGNFVNDNTLTVTIKRLREKLKNPPCIKTLRGIGYRME
                     DS"
     gene            complement(7071..>7600)
                     /locus_tag="KR294_003774"
     CDS             complement(7071..>7600)
                     /locus_tag="KR294_003774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH0241780.1"
                     /translation="ELAKEVEYTKRTIYKYFSCKEDLFFAVVLRGYKRLWDNVKIESA
                     KGKTGFEKIKLSYFAFHKFYSVEPSLLCLMGMIGIVNSEKSDTDMLFKEKFFSFNKFM
                     FDEIQGMFEIGKNDRSIRHDIEIPTLMYSSIFTLTGFFNLLSVTGKSYLNNFNIDEEK
                     FIETTLALLIDSIKA"
BASE COUNT         2825 a          969 c         1192 g         2614 t
ORIGIN      
        1 attgtaatat ttaaatatta caatagtaag ttttaaatgt ggaatcaatt actatatcac
       61 aaattaaaag gaggacagga tgttattaat agttacctaa ttatcttcgc aataggttta
      121 atcaacataa ttgtactagg tgaagaaaat ataagagata cagctattca tttagtcttg
      181 tttcttataa gtagaaccta gattggagta tattacaaat aatgtctact attttaatag
      241 taggttataa atttaaatat gggagatgat ataaattatg aaaagaaaaa agaattttat
      301 ttggatagct atcttattgg ttggtgtagt tatggtaatg tattatgtag ggaaaaaaca
      361 taacgatata aatcaaaaaa ctgataagaa ttatataaaa tctgaattaa ataagtctga
      421 attaaataaa tccaaaattg aaaacaatga taaaaacaaa aaagaaaaaa ttaatatggt
      481 tgactatagt gattgttttg aaggtattag tggaggagct attttttata atactaaaaa
      541 taaagaatat aatatatata acaaagaatt aattgaaaca agaaggtcac catgttctac
      601 ttttaaaata gtttcaactt taattggttt agaaaaaggg gtaataaact caaaagaatc
      661 agttatggga tatgatggta cagagtatcc aaataaaaat tggaataaaa atcttagttt
      721 agaagaggca tttaaggagt cttgtgtttg gtattacaaa aaattgatag ataaagttga
      781 tgctaaatct gtccaaaaca ttttagatga tttaaagtat gggaattgcg atattagcga
      841 atgggaaggc gatttaaaaa atggaaaggg acatttaaat ggattttggt tagaatcttc
      901 attacaaata tctccaaaag aacaagtgca aacaatggca aaaatatttg agggagatac
      961 aaactttaaa aaagagcata ttaatatttt aagagatatt atgaaaatag atataaatga
     1021 taaaaacata aatgtatatg gaaaaactgg aacaggattt gatgaaaaaa ataaacgtgt
     1081 ggatgcatgg tttgttggta tgctagagcg tgaaggtgac acctattatt ttgctattaa
     1141 atcagatgat tccaataaag aaattacagg gccaaaggta aaggaaattg caattaatat
     1201 aattaagaaa tattatagtg taagggaata aacttaattt tatttgtaaa tattatttac
     1261 ctatagtctg taatatttat taaataattt tactaaattg agtctatata gagcaaaact
     1321 cctttagtac ataaaatact tgctattgat tattaaattg aatacctata gatttaaagt
     1381 taataccttt taaagactat gtaatatatt aaaagtataa ataaaatata ttgcatagtt
     1441 tttgttttat attataattt taaataatgt gcaaaaacta aacaatattt ttaatagtaa
     1501 tttatatttg tattcatgtc actataatgt cattttaggt tgctaaaatt taaccataaa
     1561 ggagatgatt gtatatggaa atattaaaat gtgaaaatct cacaaaaata tatggttcaa
     1621 atcaaaccag agtgacagcc cttaataatg taaatttatc agttcaaaaa ggtgattttg
     1681 tatccattgt aggagcatct ggttctggca aatctacatt gttacatctg cttgggggag
     1741 tagatagacc tacatctgga aagatttatg ttgaagatac agaaatatca agtttaaagg
     1801 aagaagctct tgcagttttt agacgtagaa aagtaggtct tatttatcaa ttttataatc
     1861 ttatacctac ccttgatgtt agaaaaaata tattattacc catgttactt gataaaagaa
     1921 aggtggatga ggatagattc tctgagattg tatctatatt gggattatct gatagattaa
     1981 accatcttcc aagtcaactt tcaggtggac aacaacaaag ggtatctata gctagaagtt
     2041 taatctatag accagctatt ttattagcag atgagccaac tggtaatctt gatagaaaaa
     2101 attcagaaga aattgtagac ttgttaaact tatcaaataa acgatttaat cagacaatac
     2161 ttcttattac tcatgatgag aaaatagcac tagaggcaaa tcgtattgta actatggaag
     2221 atggagtgat tgtctctgaa aaggtggtga agaaatgaat attcttcaag aatacacctt
     2281 agactttgta cgacgcaata aacgtagtag tatagctata atgttagcta tattacttac
     2341 tacaaccatg atgtcttctt tgtgtggact gttgtatacc atgtggacag attttataag
     2401 actttcaatt gagaaagaag gtaactggca tggtgaattg tttgactata cttatggaag
     2461 tgacttacca ttaattgaaa atttttcttc agttgatgat gtaatggtaa aaggacaatg
     2521 gtatgtaggc aaaattaatg atgagaaaag agattatata atttatagaa atgctacatc
     2581 agagtattgg aattctatgc cagaaaagga tactataata gagggtcgtc gaccaaataa
     2641 tgctaatgaa attgcattat caaaacaata ttttgagaat aatccaagtg taaaaattgg
     2701 tgataaaatt actctcccaa taggatatag aatcttaaat ggaaagcctc ttgaacccat
     2761 agccccaaaa tcgaaagggg aaagttttaa aaaaatttca gaggctacat tgacaatagt
     2821 aggaaaggta gatgtttcta cttcatcagt aatacctgca tatacagctc ttggatatct
     2881 tgataaaaca agtataaaac ctaatgatag tataactgtg tacttgcgat ttaaaaatat
     2941 aagagacacg tataaggaac ttccaaaact tgctaaatca ttgggatgga agactaatga
     3001 atatggaaaa tacaatctta aatacaatag taattatctt ttaaagatgt tagtcttttc
     3061 accagaacag aaagcatcta tgagtagtat atcaaaattt tcaactccta ttatgtatct
     3121 tacaatagca atttttacag tagccgtgtt tgtaatggtg atttacaacg cgttttcact
     3181 gtctgcaaat gctagactta ctcagttagg gatattatct agtgttggtg catcaccaaa
     3241 acaaattaaa aggtctgtag tgtttgaagg ctttttactg acaattatac cattaccaat
     3301 aggtttattt ttaggatggt tattgtgtaa taggcttata gtttatgtta attcagttaa
     3361 ttatcatact gatgttccag aagtggtatt tacttatggt attcctgctt ttctgccagc
     3421 agttttactt acaatagtaa cagtctggat ttctgcactt ataccagcac gaaaagtatc
     3481 aaagatatct cctatagaag caatacgaca aggagatagt gttaaaatca aaaagtcgca
     3541 taaatattca ttaggaaaga tatttggaat agaaggagaa cttgcatcaa acgcactacg
     3601 tgctcgtaaa aaatcttatc gtactgcaac aatatcttta acattatctt ttttattact
     3661 tacatgtttt ttgcatataa ttgcaaatca agaaggagca aaagctgttt atggaagtga
     3721 taattataag gaccaaagag atatagcagt ttatttggaa aatagtgaac ctatagagtc
     3781 tgctttcatt gaaaaattag ataatacaga aggtgtaaaa agttcactat attatcaaaa
     3841 aatgtctgct tccacttggc tgactgaaaa agatgcatca aaagaacttg cgaaaaatgg
     3901 aggatttaaa agtatagttt catctaaaaa atactctcct atagaacgtg atggcaagtt
     3961 tcgtataatt tcaaatataa ttgggcttga tgataagagt tttacagaat attgtaggca
     4021 aatttctgta gacccaaagt tattttataa tacaaaaaat ccaacctcaa ttgtatataa
     4081 taaggaggaa gatattaatc gtagtacacg tagaaataaa gtatatatag attatttaaa
     4141 tctttcaata ggagataaca ttaaattaaa tgaaaaagta tatgacgaag ataaagggga
     4201 ttatacttac aacatgaaag tgggagctat tacaagcaca cttcctaaaa tagtagatac
     4261 tagttcaaag tatacattaa tgcaaatagt tccaatgtct atggtacagg aaatatctaa
     4321 aaattatgat gaagtaagta ggttacgttc aaataggctg ataggagtat ttaaagtaaa
     4381 taatcgtgag gacattccta gagtaagaga aaaattagag tccatttata ataaagacta
     4441 tggttcagga gattatagta ttgaggatgt tttagaaagt gaaaaacaaa aggctagtgg
     4501 aataaagacc atgaatttaa tagtaggctt tattacaggt ttattggcta tgattggatt
     4561 atcaaatgta cttgctacag tgtcaggaaa tattagaagt agacgacaag agtttgctat
     4621 gttgcgttct gttggattat ctccagaagg cataaaaaag atgcttattt tggaaggttt
     4681 attcttagga attacaccat tactacttag tattcctgtg caaataggaa tagtgtatgc
     4741 ttttctacgt ataaatgaaa tatattttat agagtattta ccatttgcac ctatatctac
     4801 aataataggt tttactatat tgatactttt tattgtaata gcatcatata tgacaggata
     4861 caagcagttg aagaatgaaa atatagtaga atctataaaa aatgaaacaa tataaacaaa
     4921 atctatttga acttatttaa aggtttcgat ttaagactac ttacaagtat agggatagtt
     4981 aagttgtttg tttaataaaa ccttaaatgt aaatagaagt atattactaa aacaatagat
     5041 aacatagaat atagatatag ctggattata ggtattttac ctataatcca gcattttatg
     5101 tgtaaaattt aattatgaat cttgcaccac cattatggca attttctgca tgtagagtac
     5161 cattttgacg ttctataata gactttgata gagcaagccc tataccaata ctgtccttac
     5221 tagcattttt accacgataa aatctattaa aaatatatgg aagttcttcc tgagcaaacc
     5281 ccttaccatt atcttctatg ataatctcaa catatagagg attttgacta taataagcaa
     5341 ctatatatcc accatcttct atatgctcac tacaattttt aagaatattt aaaagagctt
     5401 ctaaagtcca attaatatcg atttcaaatt ctaccgaagg agaagcctcg atagtaaatg
     5461 tctgatgttt ttctcttaaa gaaccttcta taggctcaat tgcataagta agaagagaat
     5521 gtacatctat aagtttgctt tcaaatatta aagtacttgc atccaatttt gataatgtaa
     5581 gtaaagatga aactagtctc tcaagtcttg agatttgatt tgtaagtctg ttaatataat
     5641 ctatttcttc atctggacaa ttttctgaaa gtaattgtgc cataagtgac atagaagtaa
     5701 ttggagtctt aagttgatga gcaatatctg caagattatc tgaaagagtt tgtctttctt
     5761 ttaaagcaaa ttcttttgaa caacgaagtt ccccaactgt tttatatatc tcatcttcaa
     5821 ggtgagaaaa ttcatcttca catcgtaaaa gtacagactc ttttcctaaa ttcacttctt
     5881 ctaagtattg agtaagattg tttattctac tcagtttttg cttatttgtt ctatgtttga
     5941 ttatatatat aactgtagcc attgttgaaa ttataccaaa cgatatcact agaaaataaa
     6001 aaaagttttt actccaaaat gtacttttag aatatccatg ttttgataaa atttcatttc
     6061 ctgttttaaa atccttatca ctagaatttt tcagtgattt tagtatactt tctgtagact
     6121 taggattgta ctcatatgat gcaccaagag ccttagacag tacattgtat tcattaaaag
     6181 aagttatagt tgttagaatt acactcaata aaaaagttac aattaagcag aatattataa
     6241 aaacaactgt actgttgata tttcttggag ttttcactag ctgtcctcca ttctatatcc
     6301 tatgcctctt aacgttttta tacaaggtgg attttttaat ttttctctaa gacgttttat
     6361 tgtaacagta agagtgttat catttacgaa attaccatct acatcccaga gcatttctag
     6421 taactttgta cgagtcatag ctctattttt attttccata agacttagaa gaagtttata
     6481 ttctcctgct gtcaaaggta cttcaacatt atctaaatat gctttgactt caaccttatt
     6541 caagcttata ttttcacatg taatagtatt gttagtattt gaatgagttc ttctaagaac
     6601 tgcattaatt ctggactgaa gtactgagag caaaaacggt ttaaccacat agtcatctgc
     6661 acccatatct aatccacgta taatgtcttt ttcatcatca cggactgtca aaaatatcac
     6721 tggagtatct tctatacttt taacatattg gcaaaactcg tatccaatac catcaggtag
     6781 atttaaatca agcagaatta aatcaatagt tttatcaaaa ttttttttag cttcagcaat
     6841 cgtattataa caacatacag tgtgattttt cttttcaagg gaagttttta ttccaaatgt
     6901 aattgtatca tcatcttcta aaagaagtat tttagccatt tacttttaat cctttcagta
     6961 atttagttat tccattaact aagttattag ttttatgttt aatatttttt atattagaga
     7021 tagaaaaaat tatcatttaa gtatataaac tttaatttat aaacttaggt ttatgcttta
     7081 attgaatcta ttaaaagagc aagagttgtt tcaataaatt tttcctcatc tatattaaag
     7141 ttgttcaggt atgattttcc tgttacagat agtaaattaa aaaatcctgt aagtgtaaat
     7201 attgatgaat acataagagt aggtatttca atatcatgcc taatacttct atcatttttt
     7261 ccaatttcaa acattccttg tatttcatca aacataaatt tattaaaaga aaaaaacttt
     7321 tctttaaaca gcatatcagt atccgatttt tcagagttta caataccaat cattcccata
     7381 aggcataata gagaaggttc tacagagtaa aatttatgaa aagcaaagta tgaaagtttt
     7441 attttttcaa accctgtttt gccttttgca ctttctattt taacattatc ccaaagtctt
     7501 ttatatcctc ttaagacaac agcaaagaat aaatcttctt tacatgaaaa gtacttgtat
     7561 atggtgcgtt tagtatattc aacttctttt gctaattcat
//
LOCUS       DAEPKC010000224         5745 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.guided.157, whole genome shotgun sequence.
ACCESSION   DAEPKC010000224 DAEPKC010000000
VERSION     DAEPKC010000224.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5745)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5745)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5745
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.guided.157"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..508
                     /locus_tag="KR294_003775"
     CDS             <1..508
                     /locus_tag="KR294_003775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBH0241781.1"
                     /translation="MIDGIAEAFILNVKGNISTIHLYRSGSFFGEMEQFNDGKKPVEI
                     VAFTDCNVYKLHRDDFLNWLRGDFEATKFLIREISSKLVVNAELIEELSSLSVKERLL
                     RCISLHYYRSELNLLTKKQLASEVNAPIRSINRAINECVQEHLIAYENKRFSVINQRE
                     VLKNLPTT"
     gene            658..1062
                     /locus_tag="KR294_003776"
                     /pseudo
     CDS             658..1062
                     /locus_tag="KR294_003776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433844.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="oxalate:formate antiporter"
     gene            1187..2113
                     /locus_tag="KR294_003777"
     CDS             1187..2113
                     /locus_tag="KR294_003777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0241782.1"
                     /translation="MSDILSRITNKIGDKNIVDKLSALSKSDLNSLLLEVFDRQANTL
                     TATDILKSYQLNRFTIPSGIDPEEIHALESKLLRKAFNMDIKTIMLSPSAPLGSCSVF
                     GSVDQYNVVSALRGTETLADPSNMLAIIIADKLKRKEENNTIPIHMATTARVIRAQNF
                     VGKGLYSHFGLYCMVSSGIDTGSYTCEKMLLEKHLNYYKDILSEIENVRFSIILRKRN
                     GYKDNDGFFDRMVETIKLIFPNIELSIHNDDVDNNYYKGINFKLSVKQGNETVEIVDG
                     GFVDWTYQMLGNKKERCLISGIGLERFLVAVS"
     gene            2127..2576
                     /locus_tag="KR294_003778"
     CDS             2127..2576
                     /locus_tag="KR294_003778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH0241783.1"
                     /translation="MELIEWNYAYITDLVEFANDKEIAKNLRDNFPHPYREQNARDFV
                     SFCLATPDVKQLSYAIFYQERAIGSISLTFEEDTSINKNAELGYWLARNYWGKGIATN
                     AVKEICKIAFEKYNLNKIHANVYSYNRGSSKVLEKCGFKIEEYCHNS"
     gene            2936..3343
                     /locus_tag="KR294_003779"
     CDS             2936..3343
                     /locus_tag="KR294_003779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBH0241784.1"
                     /translation="MVDEKTIEHQFDSFCKTVLRNYARDIYDENKRRNDYLVSLESLS
                     LAELSKLSILDDYDSNYICMVSYDYNIRIEDVLMAQAIGKLTKRKQDIILLSFFLNMT
                     NADIATLMDLAENTIHYHKTNALKELKELMEEH"
     gene            3345..3575
                     /locus_tag="KR294_003780"
     CDS             3345..3575
                     /locus_tag="KR294_003780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH0241785.1"
                     /translation="MKPTKEVLPFTIILLAVHGDVNAINGILKHFEHYIIRLSQKTLF
                     DEYGNPYIHVEEETKRMLGTKLITAILRFNLS"
     gene            3965..4168
                     /locus_tag="KR294_003781"
     CDS             3965..4168
                     /locus_tag="KR294_003781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HBH0241786.1"
                     /translation="MNNTDVPIWEKYTLTIEEASKYFRIGEKKLRKLADENLDSGWVI
                     MNSNRIQIKRKQFEKIVDTLDFI"
     gene            4246..4599
                     /locus_tag="KR294_003782"
     CDS             4246..4599
                     /locus_tag="KR294_003782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase DNA-binding domain-containing protein"
                     /protein_id="HBH0241787.1"
                     /translation="MSTEKRRDNKDRILRTGESQRKDGRYAYKYVYSFGKPQFVYSWK
                     LVPTDKPPKGKRDDISLRDKEKAIQNDLDDSIDTIGKKMTVCQLYAKKNGLRKNIRLN
                     TKKGRHYLMKILNKE"
     gene            4671..5303
                     /locus_tag="KR294_003783"
     CDS             4671..5303
                     /locus_tag="KR294_003783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CatB-related O-acetyltransferase"
                     /protein_id="HBH0241788.1"
                     /translation="MTIPSSNKVYPRSNDYQTVYLKNVITRENIEVGDYTIYNDFYND
                     PRDFEKNNVLYHYPINNDKLIIGKFCSIACNAKFLMTSGNHSMKSKSTYTFPIFYEEW
                     KLDINHITDAWDNKGNIIIGNDVWIGYDSIIMSGVNIGDGAIIGTRAVVTNDVPPYSI
                     VGGVPAKIIKKRFNNDTISKLLEIKWWDWPYKKIQSNIKHIQSGNIDKLV"
BASE COUNT         2134 a          784 c          953 g         1874 t
ORIGIN      
        1 tatgattgac ggtattgcag aagcattcat cttaaatgtg aaaggaaaca tctcaactat
       61 tcatctttat agaagtggta gtttttttgg agaaatggaa caatttaatg atgggaaaaa
      121 acccgttgaa attgtcgctt tcacagattg taatgtatat aaacttcata gagatgattt
      181 tttaaactgg ttaaggggag attttgaagc tacaaaattt ctgattcgag aaatatctag
      241 taaattagtt gtaaatgctg aattaattga agaattatca tctttaagtg ttaaagaacg
      301 acttctgagg tgtatatcct tacactatta tagaagtgaa ttaaatctgc ttaccaaaaa
      361 acagcttgct agcgaagtaa acgctccaat tagaagcatt aatcgtgcta taaatgaatg
      421 tgtacaagaa catctaattg cttatgaaaa caaaagattt agtgtaatta atcagcgaga
      481 ggtattaaag aatcttccta caacataagt ataatttcaa aaaagtattg aataataatt
      541 attcaatgct tttttatttc gggtcaagtg acctattttt ttttattttt tcattatata
      601 atactcctat gcataattat gttggattga tagctaataa aagaaagtga gaggtgttat
      661 actaaaaaag aagcatactt cccaactcca gacttacagt ggattgaaga tagattttgg
      721 atttgggttc attacgcttg cactaagatt ggacgtagag aactatttga aacaattgat
      781 tttttatctt ttttaagaca atcagtactt gccccattaa tacagcttct cttaggtaaa
      841 ttacctcgtg gagttagaaa aattgaattg gacgcacccc aatatattga agcattagaa
      901 aagacggttg ctaaccatga atataaaagc tgtgttaatg cattgcaggc tactatcaac
      961 ctgtatcttg agttaagaga ggaattatca caaagtccta ttgtccgaaa ggttgaagct
     1021 gaaagggttg cattacagta ttttcaagat ttaatcaaat aaacccaaag taaaaaaata
     1081 ttgaatagta aatattcagt gttttttcat ttttggtcaa atgacctaga ttagttgttg
     1141 taaccattct ataattattt tgaaagtaac agtatggagg ataactatga gtgatatttt
     1201 aagtagaatt acaaataaaa ttggggataa gaatatagtt gataagttat cagctctatc
     1261 aaaatcagat ttgaactcac ttctattaga agtgtttgat agacaagcaa atactttaac
     1321 tgcaactgat attctaaagt cataccaact aaatagattt actatcccta gcggtataga
     1381 tccagaagaa attcatgctt tggagtcaaa attattgaga aaagcattca atatggatat
     1441 caagacgatt atgctttctc cctctgctcc attaggtagc tgtagcgttt ttggctccgt
     1501 agatcaatat aatgtagtaa gtgctctacg agggacagaa acacttgcag acccctcaaa
     1561 tatgttggca ataattattg ctgataaatt aaaaagaaaa gaagaaaata ataccatacc
     1621 tatccacatg gctactactg ctagggtaat aagagcacaa aattttgtag gtaaaggttt
     1681 atattcacat tttggcttat attgtatggt ttcatctggt atagatacag ggtcttacac
     1741 ttgtgaaaaa atgttgttag aaaagcactt aaactattat aaagatatat taagtgaaat
     1801 agaaaatgtt cgtttctcta ttattctacg caaaagaaac ggatacaaag ataatgacgg
     1861 atttttcgac agaatggttg aaactatcaa acttattttt cctaatatag agttatcaat
     1921 tcataatgat gatgttgata ataattatta taaaggtatc aatttcaaat tatcggtcaa
     1981 acaaggaaat gaaaccgttg aaatagttga cggtggattt gttgactgga cttatcaaat
     2041 gcttggaaat aaaaaagaac gctgtttgat aagtggtatt ggcttagaaa gatttcttgt
     2101 agctgtttca taaaaggaga agaaaaatgg aacttataga gtggaattat gcttatatta
     2161 ccgatttagt tgagtttgcg aatgataaag aaattgcaaa gaatcttcgt gacaacttcc
     2221 cccaccctta tagggagcaa aacgctagag attttgttag tttttgtttg gcaactccag
     2281 atgttaaaca acttagctat gctatttttt atcaagaaag ggctattgga agtatcagcc
     2341 taacatttga agaagatacc tctattaata aaaatgctga attaggttac tggcttgcta
     2401 ggaactattg gggcaaaggg atagcaacaa atgcagtaaa agaaatatgc aaaattgcct
     2461 ttgaaaaata caaccttaac aaaattcatg ctaatgtata ttcctacaat agagggtcaa
     2521 gtaaagtatt ggaaaaatgt ggttttaaga ttgaagaata ctgtcacaat tcataataaa
     2581 gaatagaaac atgattgatt gccatgtata tagtttaatt cgaccgcaat agcatttatt
     2641 agaattaacc tactttttaa taacagaata agtttttccc ctctattaat ttcttatgca
     2701 tctttgtatt tttatgaaaa gctagccaat gcatatttcc atacatcaat atggtggtgg
     2761 cttacaacca atataaatta aatacgtttt aaagaataca catttttgcc ctataggcag
     2821 agtgtgtatt tttttctctt ttttttgaaa tttatcgaag atttaacgcc ctcccaccgt
     2881 gataggagta agcaaggtta tttaactcct tgcgatggaa agagggtgaa atcttatggt
     2941 tgatgaaaag acaattgaac atcaattcga cagtttctgt aaaacagttt tgcgtaacta
     3001 tgctagagat atttatgacg aaaataaacg cagaaatgat tatttggtat ctctcgaatc
     3061 tttgtcactt gcagaattaa gtaaattgag tattttagat gattatgatt ctaactacat
     3121 ctgtatggtt tcttacgact acaacatacg aattgaagat gtattaatgg cacaagcaat
     3181 cggaaaactt acaaaaagaa aacaagatat aattctactt tcattctttc tcaacatgac
     3241 aaatgctgac atagcaacat tgatggattt agcagaaaat accatacatt atcacaaaac
     3301 aaatgcacta aaagagttga aagaactcat ggaggaacat tgaaatgaaa cctactaaag
     3361 aagtattacc ttttacaatt attttacttg ctgtacatgg cgatgtaaat gcaataaacg
     3421 gaatacttaa acattttgaa cactatatca ttcgtctttc acagaaaact ttatttgatg
     3481 aatacggaaa tccctatatt catgtagaag aagaaacaaa gcgaatgcta ggaacaaaac
     3541 taatcactgc tattttgaga tttaatttgt cttaatctcg ccctctctcc atgtatcaag
     3601 ctatttggta catggagaat cactaattat ttgtctataa aagcccataa gctattgtga
     3661 ttttttatag acaaatcaat gccgactgtt ctttgacaac tgaataaagt agatagatac
     3721 gtttgtgata cagatagcca acaaatacta tacgccatga ccttaatcaa gagagctact
     3781 atatagtgat ttgtgaataa cctttggaac ggttgttttg ccgtaacctg taccacagta
     3841 taatgataca cctgtatgac acggttctgc ccataagaat gggattggtt aaaataccaa
     3901 tggagcttac caaagccatc tatctacttc tgaactacga acatagaaag gagtgataca
     3961 ttctatgaac aatactgatg tacctatttg ggaaaaatat accttgacga ttgaagaagc
     4021 gtcaaaatac tttcgtattg gagagaaaaa attacgtaaa cttgctgatg aaaaccttga
     4081 ttctggctgg gtcattatga atagcaatcg cattcaaata aagagaaaac aatttgagaa
     4141 aatcgttgat acacttgact ttatctaatg aaattgagcc ttatatgtta taatattcat
     4201 atgacgtatc aagctcaatt cggttattga gaggagcttc ttatcatgtc aactgaaaaa
     4261 agacgagata ataaagatag aattttaaga actggagaga gccagagaaa agatggaaga
     4321 tacgcatata agtatgtata ttcatttggt aaaccacaat ttgtttactc ttggaaactt
     4381 gtacctactg ataaaccccc aaagggaaaa cgtgatgata tatcattaag ggataaggaa
     4441 aaagcaatac aaaatgacct tgatgatagc attgacacta ttggtaagaa aatgacagtt
     4501 tgtcagttat acgctaaaaa gaatggacta agaaagaata tccgacttaa cactaaaaaa
     4561 ggacgccatt atcttatgaa gattcttaac aaggagtgat tctgtgaaga gatgtattgt
     4621 agtagtggaa tagtcaaaaa cataatatat attaaaggag agatttaaat atgactattc
     4681 caagttcaaa taaggtatat ccaagaagta atgattatca aactgtatat cttaaaaatg
     4741 taataacaag ggaaaatata gaagttggag attacacaat atataatgac ttttataatg
     4801 acccaagaga ttttgagaaa aacaatgtat tgtatcatta ccctataaac aatgataaat
     4861 taataattgg taagttttgc tcaatagcat gtaatgcaaa atttctaatg actagtggaa
     4921 atcactcaat gaaatcaaaa tccacatata cttttcccat cttttatgaa gaatggaaac
     4981 tcgatatcaa ccatataacg gacgcttggg acaataaggg taacattata attggaaatg
     5041 atgtgtggat aggttatgat tctataatta tgtcaggtgt aaatattggt gatggtgcaa
     5101 ttattggaac aagagcagta gttactaatg acgttccacc gtattctatt gttggaggag
     5161 tacctgcaaa aattataaaa aagagattta ataatgatac aatttcaaaa ttattagaaa
     5221 ttaaatggtg ggattggcca tataaaaaaa ttcaatcaaa cattaagcat attcaatcag
     5281 gaaatattga taaattagtt taatatttta taatttattt atattaaact ttactttaat
     5341 aatcatttta taagagcttt ttcaaaattt gtatattatt ttaatatata taaatttaat
     5401 acaacattaa ataaaataaa aagtaaagtt acttaataaa aagttacttt actttttatt
     5461 atttaaattc ctgtttttat tataataggt aaaattctat taaactagtt cacattttca
     5521 ttattattga tatattatat atgaatatac cattttgttt tttaataaaa aaatcatgct
     5581 acatcaatag taagcaacta ttaatgtagc atgatttttt gtatctaaat aatcttagta
     5641 tttacctatc aatatagatt gatatatcaa aaactatagt cttctatatt cttctctttt
     5701 tagcttttgg ttacttagat agtaatcaat ttcatcaatt agacg
//
LOCUS       DAEPKC010000225         2616 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 28A10CD0013
            SAMN05941538-rid12469613.guided.198, whole genome shotgun sequence.
ACCESSION   DAEPKC010000225 DAEPKC010000000
VERSION     DAEPKC010000225.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941538
            Sequence Read Archive: SRR6109476
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2616)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2616)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068100.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068100.1
            Genome Coverage       :: 145x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 23:51:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,786
            CDSs (total)                      :: 3,715
            Genes (coding)                    :: 3,667
            CDSs (with protein)               :: 3,667
            Genes (RNA)                       :: 71
            rRNAs                             :: 7, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 2, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 21 of 48
            Pseudo Genes (incomplete)         :: 27 of 48
            Pseudo Genes (internal stop)      :: 11 of 48
            Pseudo Genes (multiple problems)  :: 8 of 48
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2616
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941538-rid12469613.guided.198"
                     /strain="28A10CD0013"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..505
                     /locus_tag="KR294_003784"
     CDS             <1..505
                     /locus_tag="KR294_003784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBH0241789.1"
                     /translation="RRDLMEKIADVITKKQQEILVEMDKVSVDKANRFRKFVKNFTLF
                     YLKAPVLVLVFTKVYNPSGYYELELIDAPKETIDKLFIRNPGMQSLGAAIENFTLSAI
                     ELGYGSCWLTSQNYAADEIEAVLEAETGFEKGEYFLGAMLALGVPEDNLKSPSKKPVE
                     EICTFIK"
     gene            920..1636
                     /locus_tag="KR294_003785"
     CDS             920..1636
                     /locus_tag="KR294_003785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0241790.1"
                     /translation="MNSYNILVVEDEKEIADAIEIYLLNQGYNVFKGYNGLEGLKVIE
                     NQEIHLAIVDIMMPKMDGITLTMKLRENYNFPVIMLSAKSEEVDKIMGLNIGADDYVT
                     KPFKPLELLARVNSQLRRYTKYLNMVGNKEQKVESDDSVFAIGGLELNENTKEVSIDG
                     KYIKTTPIEFKILSLLMRNAGRVFSADEIYERVWNENAVNTDTVMVHVRNIREKIEID
                     PKNPKYLKVVWGVGYKIEKI"
     gene            1611..>2616
                     /locus_tag="KR294_003786"
     CDS             1611..>2616
                     /locus_tag="KR294_003786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBH0241791.1"
                     /translation="MDTKLKKFKDKYIVTIIVFILMLSASLGMISQYSTIQASAKGGA
                     ENPFEQESFVDSIYKGSYVLYHNMKEEQEGKMIQPSKLFINEETMNYIKNVSKEKDTY
                     DGSETYYTDDSINADFNENFENWEHFIKASGKNLKYYLVDKESNFEFFNDNKELGVLD
                     TTKNDASKENSNENQSKNTEMNDEERQKQITDIKENYRFYVVMNFDKDGKVNIVDSYG
                     VNQKIINQMLLSKAREDLMDTSLGGNSISYKLSPIKNITLVYAVPKVISKGDSVEYGY
                     GNTYFDDGIISYISNVENNSYYKISGMILKIILAIVVIVALAFPYRKSKELLGFDTLS
                     R"
BASE COUNT         1116 a          231 c          451 g          818 t
ORIGIN      
        1 acgccgtgat ttaatggaaa agatagcaga tgtgataact aaaaagcaac aagaaatact
       61 tgtagaaatg gataaagtat cagtggataa ggctaataga tttagaaaat ttgttaaaaa
      121 ttttacacta ttttacttaa aagctccagt tttagtatta gtttttacaa aggtatataa
      181 tccatcagga tattatgaat tagagcttat agatgcacct aaggagacta tagataaatt
      241 atttataaga aatccaggta tgcagagtct aggtgctgca attgaaaact ttacactatc
      301 agcaattgaa cttggatatg gttcttgttg gttgacaagt caaaactatg cagcagatga
      361 gatagaagct gttttagaag cagaaactgg ttttgaaaag ggagagtatt ttttaggtgc
      421 aatgttagct cttggagtgc cagaggacaa tttgaagagt ccatctaaaa aaccagtaga
      481 agaaatatgt acatttataa aataaaagtc aaggacattt taaaatcgaa gtaaattaaa
      541 aacaaaataa attaaaaata aatatttaaa aaattaaaaa gtaggtttta ttgatattaa
      601 ttttatattt caaatcatta atttaattaa tacaataaga actacttttt tttgtatatt
      661 aattttaaat atatttaaat ctttagaaaa tctttagaaa agtatatgta atatcttaag
      721 tttttaattt taatattaag tatataaaac aaaatgaaaa aatattaaat ttaaactaga
      781 aggaggtttc taagatggac attaaataca aataaccaga acaaaagata taaatatata
      841 tataaatgga aaaacttcta tcatattgta taatcatata tgtaaagaaa atttataaat
      901 taatataaag gagattagaa tgaattcata taatattttg gtggtagaag atgaaaagga
      961 gatagcagat gctatagaaa tatatctatt aaatcaagga tataatgttt ttaagggata
     1021 caatggatta gaaggtctta aggttataga aaaccaagaa atacatttag ctatagttga
     1081 tataatgatg cctaaaatgg atggtataac acttacaatg aagcttagag aaaactataa
     1141 ttttccagta ataatgctat ctgcaaaatc agaagaagtt gacaaaataa tggggcttaa
     1201 tataggagca gacgattatg taacaaaacc ttttaagcca ttagaactat tggctagagt
     1261 taattcacaa cttagaaggt acactaagta tctaaacatg gttggaaata aagagcaaaa
     1321 ggtagaaagt gacgatagtg tgtttgcaat aggcggatta gaattaaatg aaaatacaaa
     1381 agaagttagt attgatggaa agtatataaa aacaactcct atagaattta aaatactaag
     1441 tttacttatg agaaatgcag gaagagtttt ttctgctgat gaaatatatg aaagagtttg
     1501 gaatgagaat gctgtaaata cagatacagt tatggtacat gtgaggaata taagggaaaa
     1561 gatagaaatt gacccaaaaa atcctaaata tttaaaggtg gtgtggggtg ttggatacaa
     1621 aattgaaaaa atttaaagat aaatatatag ttactattat agtttttata cttatgttat
     1681 cagcatcatt aggtatgatt agtcaatatt ctactataca agcaagtgct aaaggtggag
     1741 cagagaatcc atttgaacag gaaagctttg tagatagtat atataaagga agttatgttt
     1801 tatatcataa tatgaaggaa gaacaagaag gtaagatgat acaaccatca aagctattta
     1861 tcaatgaaga aactatgaac tatataaaaa atgtaagtaa agaaaaagat acttatgatg
     1921 gttcagaaac ttattataca gatgatagta ttaatgcaga ttttaatgaa aactttgaaa
     1981 attgggagca tttcattaaa gcgtcaggaa agaatttaaa gtactattta gttgataaag
     2041 aaagcaattt tgaatttttt aatgataata aagaattagg agtacttgat acaacaaaaa
     2101 atgatgcttc aaaagaaaat tctaatgaaa atcagtcaaa aaatacagaa atgaatgatg
     2161 aggaaagaca aaagcagatt acagatataa aagaaaacta tagattctac gttgtaatga
     2221 attttgataa agatggaaaa gtaaatattg tggattctta tggagtaaat caaaaaatta
     2281 ttaatcaaat gttgttatct aaagcaagag aagatttaat ggatacaagt ttaggaggaa
     2341 attcaatttc atataagtta tctccaataa aaaatataac attagtatat gctgtaccta
     2401 aagtaataag taaaggtgat agtgtagagt atggttatgg aaatacttat tttgatgatg
     2461 gtataatttc atatataagc aatgtagaaa ataattctta ttataagatt tctggaatga
     2521 ttttaaaaat tatattagct atagttgtta ttgtagcttt agcattccca tatagaaaat
     2581 ctaaagagtt gctaggattt gatacattat caagaa
//
